A0A087YPF4_POEFO Loading...

Sushi domain containing 2

AlphaFold DB , UniProt , Accession A0A087YPF4, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 650 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M90Very high93.5Very high78 Ų7884.1 Ų84.138%0.38446%0.456SS..  0151.2061.7-177.7-67.100110.1W3 I15 F51 V70 V72M1-W3 HydrophobicContact CE-CE3 3.99Å; M1-W3 HydrophobicContact CE-CZ3 4.16Å; M1-W3 HydrophobicContact CG-CZ3 4.24Å; M1-I15 HydrophobicContact CE-CG2 3.89Å; M1-I15 HydrophobicContact SD-CD1 4.34Å; M1-I15 HydrophobicContact SD-CG2 3.61Å; M1-F51 HydrophobicContact CG-CB 3.83Å; M1-F51 HydrophobicContact CG-CD1 4.28Å; M1-F51 WeakPolarHBondContact CG-O 3.32Å; M1-F51 PolarHBondContact N-O 3.24Å; M1-F51 PolarHBondContact O-N 2.95Å; M1-F51 HydrophobicContact SD-CB 4.17Å; M1-F51 HydrophobicContact SD-CD1 3.93Å; M1-V70 HydrophobicContact CE-CB 4.45Å; M1-V70 HydrophobicContact CE-CG1 3.58Å; M1-V70 HydrophobicContact SD-CG1 3.88Å; M1-V72 HydrophobicContact CE-CG2 3.61Å
2T94.4Very high93.8Very high120 Ų12085.7 Ų85.774%0.73646%0.455SS*.BIsolated β-bridgetrans-137.7149176.748.90000109.2G49T2-G49 CarbonylContact C-O 3.45Å; T2-G49 WeakPolarHBondContact CA-O 3.44Å
3W94.7Very high94.1Very high32 Ų3279.1 Ų79.112%0.12142%0.42CS..  trans-147.7159.7177.964.995.6000111.3M1 T5 V13 I15 N47 G49 S50 F51 V72M1-W3 HydrophobicContact CE-CE3 3.99Å; M1-W3 HydrophobicContact CE-CZ3 4.16Å; M1-W3 HydrophobicContact CG-CZ3 4.24Å; W3-T5 PolarHBondContact O-N 3.44Å; W3-V13 HydrophobicContact CZ2-CG2 3.95Å; W3-I15 HydrophobicContact CH2-CD1 3.77Å; W3-I15 HydrophobicContact CZ3-CD1 4.01Å; W3-N47 PolarHBondContact NE1-OD1 3.46Å; W3-G49 PolarHBondContact N-O 3.5Å; W3-G49 WeakPolarHBondContact O-CA 3.4Å; W3-S50 VanDerWaalsContact CH2-C 3.49Å; W3-S50 WeakPolarHBondContact CH2-O 3.49Å; W3-F51 HydrophobicContact CH2-CB 3.98Å; W3-F51 HydrophobicContact CZ3-CB 3.73Å; W3-V72 HydrophobicContact CD2-CG1 4.32Å; W3-V72 HydrophobicContact CD2-CG2 4.09Å; W3-V72 HydrophobicContact CE3-CG2 4.18Å; W3-V72 HydrophobicContact CG-CG2 4.38Å; W3-V72 HydrophobicContact CZ2-CG1 4.25Å
4N94.5Very high94.4Very high88 Ų8873.9 Ų73.947%0.47139%0.392SS..  trans-75.9118.3170.4-176.6-6.4000109.7T6 L7N4-T6 PolarHBondContact ND2-OG1 2.99Å; N4-T6 PolarHBondContact O-N 3.11Å; N4-T6 PolarHBondContact OD1-N 2.72Å; N4-T6 VanDerWaalsContact OD1-N 3.07Å; N4-T6 PolarHBondContact OD1-OG1 2.93Å; N4-L7 HydrophobicContact CB-CD1 4.08Å; N4-L7 HydrophobicContact CB-CG 4.11Å; N4-L7 PolarHBondContact O-N 3.16Å
5T94.5Very high94.5Very high54 Ų5468.9 Ų68.933%0.33137%0.366SS..G310 helixtrans-64.4-22.6-176.555.60000113.2W3 L7 V8 N47 G49W3-T5 PolarHBondContact O-N 3.44Å; T5-L7 VanDerWaalsContact C-N 3.26Å; T5-L7 PolarHBondContact O-N 2.97Å; T5-V8 PolarHBondContact O-N 2.81Å; T5-V8 VanDerWaalsContact O-O 3.04Å; T5-N47 WeakPolarHBondContact CG2-O 3.29Å; T5-N47 PolarHBondContact O-ND2 3.31Å; T5-G49 VanDerWaalsContact CG2-CA 3.49Å; T5-G49 VanDerWaalsContact CG2-N 3.28Å
6T93.5Very high94.6Very high103 Ų10364.6 Ų64.663%0.63234%0.343SS*.G310 helixtrans-72.3-18.7-18068.10000113.5N4 V8N4-T6 PolarHBondContact ND2-OG1 2.99Å; N4-T6 PolarHBondContact O-N 3.11Å; N4-T6 PolarHBondContact OD1-N 2.72Å; N4-T6 VanDerWaalsContact OD1-N 3.07Å; N4-T6 PolarHBondContact OD1-OG1 2.93Å; T6-V8 PolarHBondContact O-N 2.79Å
7L91.7Very high94.6Very high88 Ų8860.8 Ų60.846%0.46132%0.323SS..G310 helixtrans-68.9-22.3178.5-63.5176.6000112.5N4 T5 Q85 A87N4-L7 HydrophobicContact CB-CD1 4.08Å; N4-L7 HydrophobicContact CB-CG 4.11Å; N4-L7 PolarHBondContact O-N 3.16Å; T5-L7 VanDerWaalsContact C-N 3.26Å; T5-L7 PolarHBondContact O-N 2.97Å; L7-Q85 PolarHBondContact O-NE2 3.06Å; L7-A87 HydrophobicContact CB-CB 4.04Å; L7-A87 HydrophobicContact CD1-CB 3.94Å
8V93Very high94.6Very high2 Ų257.5 Ų57.51%0.01231%0.305CS..SBendtrans-128.5101179.9-174.70000108.5T5 T6 S10 V13 N47 V72 A87T5-V8 PolarHBondContact O-N 2.81Å; T5-V8 VanDerWaalsContact O-O 3.04Å; T6-V8 PolarHBondContact O-N 2.79Å; V8-S10 VanDerWaalsContact C-N 3.28Å; V8-S10 PolarHBondContact O-N 3.11Å; V8-V13 HydrophobicContact CB-CG1 4.41Å; V8-V13 HydrophobicContact CG1-CG1 3.86Å; V8-N47 PolarHBondContact O-ND2 2.88Å; V8-V72 HydrophobicContact CG2-CG1 4.45Å; V8-V72 WeakPolarHBondContact CG2-O 3.36Å; V8-A87 HydrophobicContact CG2-CB 4.22Å
9N90.1Very high94.6Very high148 Ų14854.5 Ų54.579%0.79129%0.289SS*.  trans-77.475.4-176.9-169.220.4000111.8
10S95.3Very high94.7Very high36 Ų3652 Ų5225%0.25228%0.276SS..SBendtrans-155.1149.1179.4-161.30000111.7V8 K12 N47 S74V8-S10 VanDerWaalsContact C-N 3.28Å; V8-S10 PolarHBondContact O-N 3.11Å; S10-K12 VanDerWaalsContact C-N 3.31Å; S10-K12 WeakPolarHBondContact CB-O 3.45Å; S10-K12 PolarHBondContact OG-O 3.2Å; S10-K12 VanDerWaalsContact OG-O 3.08Å; S10-N47 WeakPolarHBondContact O-CB 3.21Å; S10-N47 PolarHBondContact O-ND2 3.13Å; S10-S74 WeakPolarHBondContact CB-OG 3.09Å; S10-S74 PolarHBondContact OG-OG 3.2Å
11E96.6Very high94.6Very high176 Ų17651 Ų5182%0.82227%0.27SS*.SBendtrans-70.3-29.9174.4-65.3-174.617300112.4N47E11-N47 PolarHBondContact O-N 2.84Å
12K97.8Very high94.8Very high103 Ų10348.5 Ų48.545%0.44826%0.257SS..EExtended strand (participates in β ladder)trans-129.2143.1-178.3-65.9-173.9177.4-171.80111.5S10 D44 H45 S75S10-K12 VanDerWaalsContact C-N 3.31Å; S10-K12 WeakPolarHBondContact CB-O 3.45Å; S10-K12 PolarHBondContact OG-O 3.2Å; S10-K12 VanDerWaalsContact OG-O 3.08Å; K12-D44 HydrophobicContact CD-CB 4.13Å; K12-H45 CarbonylContact C-O 3.56Å; K12-H45 VanDerWaalsContact CA-O 3.28Å; K12-H45 WeakPolarHBondContact CA-O 3.42Å; K12-S75 VanDerWaalsContact C-OG 3.31Å; K12-S75 PolarHBondContact O-N 3.22Å; K12-S75 PolarHBondContact O-OG 3.03Å
13V97.9Very high94.7Very high0 Ų045.9 Ų45.90%024%0.241CC..EExtended strand (participates in β ladder)trans-128.8147.1-177.7-64.10000112.6W3 V8 I15 H45 N47 V72 S73 S75W3-V13 HydrophobicContact CZ2-CG2 3.95Å; V8-V13 HydrophobicContact CB-CG1 4.41Å; V8-V13 HydrophobicContact CG1-CG1 3.86Å; V13-I15 HydrophobicContact CG2-CG1 4.46Å; V13-H45 HydrophobicContact CG2-CB 4.38Å; V13-H45 WeakPolarHBondContact CG2-O 3.47Å; V13-H45 PolarHBondContact N-O 2.89Å; V13-H45 PolarHBondContact O-N 2.93Å; V13-N47 HydrophobicContact CG1-CB 3.98Å; V13-V72 HydrophobicContact CB-CG1 3.7Å; V13-V72 HydrophobicContact CG1-CG1 3.91Å; V13-V72 HydrophobicContact CG2-CG1 3.8Å; V13-S73 CarbonylContact C-O 3.45Å; V13-S73 WeakPolarHBondContact CA-O 3.5Å; V13-S73 VanDerWaalsContact CB-O 3.31Å; V13-S73 WeakPolarHBondContact CB-O 2.96Å; V13-S75 VanDerWaalsContact CA-OG 3.27Å; V13-S75 WeakPolarHBondContact CA-OG 3.37Å; V13-S75 PolarHBondContact N-OG 2.84Å; V13-S75 VanDerWaalsContact N-OG 3.14Å; V13-S75 PolarHBondContact O-OG 3.03Å
14N97.3Very high94.7Very high6 Ų646.7 Ų46.73%0.03226%0.259CS..EExtended strand (participates in β ladder)trans-92140.3163.2-62.1-17.2000108.1E16 D44 V72 S73 S75 Y77N14-E16 HydrophobicContact CB-CG 4.31Å; N14-D44 PolarHBondContact OD1-N 2.89Å; N14-V72 WeakPolarHBondContact O-CA 3.44Å; N14-S73 PolarHBondContact N-O 2.93Å; N14-S73 PolarHBondContact O-N 3.22Å; N14-S75 PolarHBondContact N-OG 2.89Å; N14-S75 WeakPolarHBondContact OD1-CA 3.45Å; N14-S75 WeakPolarHBondContact OD1-CB 3.31Å; N14-S75 PolarHBondContact OD1-OG 3.31Å; N14-Y77 PolarHBondContact ND2-O 3.42Å
15I96.7Very high94.6Very high0 Ų048.9 Ų48.90%027%0.267CS..EExtended strand (participates in β ladder)trans-117114.9175.6-54-177.4000107M1 W3 V13 S40 L41 T42 F51 V70 R71 V72M1-I15 HydrophobicContact CE-CG2 3.89Å; M1-I15 HydrophobicContact SD-CD1 4.34Å; M1-I15 HydrophobicContact SD-CG2 3.61Å; W3-I15 HydrophobicContact CH2-CD1 3.77Å; W3-I15 HydrophobicContact CZ3-CD1 4.01Å; V13-I15 HydrophobicContact CG2-CG1 4.46Å; I15-S40 CarbonylContact O-C 3.52Å; I15-S40 WeakPolarHBondContact O-CA 3.3Å; I15-L41 HydrophobicContact CB-CB 4.43Å; I15-L41 HydrophobicContact CG2-CB 4.24Å; I15-L41 HydrophobicContact CG2-CD1 3.97Å; I15-L41 PolarHBondContact O-N 2.89Å; I15-T42 HydrophobicContact CB-CG2 3.84Å; I15-T42 HydrophobicContact CD1-CG2 3.65Å; I15-T42 HydrophobicContact CG1-CG2 3.74Å; I15-T42 PolarHBondContact N-O 3.34Å; I15-T42 PolarHBondContact O-N 3.29Å; I15-F51 HydrophobicContact CD1-CB 3.39Å; I15-F51 HydrophobicContact CD1-CD1 3.71Å; I15-F51 HydrophobicContact CD1-CD2 3.96Å; I15-F51 HydrophobicContact CD1-CE1 4.45Å; I15-F51 HydrophobicContact CD1-CG 3.42Å; I15-F51 VanDerWaalsContact CD1-CG 3.42Å; I15-F51 HydrophobicContact CG2-CD1 4.41Å; I15-V70 HydrophobicContact CG2-CG1 3.62Å; I15-R71 CarbonylContact C-O 3.46Å; I15-R71 WeakPolarHBondContact CA-O 3.47Å; I15-V72 HydrophobicContact CG1-CG2 4.4Å
16E95.4Very high94.5Very high0 Ų048.5 Ų48.50%027%0.265CS..EExtended strand (participates in β ladder)trans-122.4146.1-166.7-57.3175.9171.500111.3N14 W18 Y37 V70 R71 D79 G80N14-E16 HydrophobicContact CB-CG 4.31Å; E16-W18 PolarHBondContact OE2-NE1 3.1Å; E16-Y37 HydrophobicContact CB-CD2 4.23Å; E16-Y37 HydrophobicContact CB-CE2 3.99Å; E16-Y37 HydrophobicContact CG-CD2 4.44Å; E16-Y37 HydrophobicContact CG-CE2 3.95Å; E16-V70 CarbonylContact O-C 3.55Å; E16-V70 WeakPolarHBondContact O-CA 3.41Å; E16-R71 HydrophobicContact CB-CB 4.39Å; E16-R71 VanDerWaalsContact CD-NH2 3.34Å; E16-R71 PolarHBondContact N-O 3.17Å; E16-R71 PolarHBondContact O-N 3.03Å; E16-R71 IonicContact OE1-NH2 2.92Å; E16-R71 PolarHBondContact OE1-NH2 3.31Å; E16-R71 IonicContact OE2-CZ 2.72Å; E16-R71 IonicContact OE2-NE 2.68Å; E16-R71 PolarHBondContact OE2-NE 3.18Å; E16-R71 IonicContact OE2-NH2 3.82Å; E16-R71 PolarHBondContact OE2-NH2 3.17Å; E16-D79 WeakPolarHBondContact OE1-CA 3.46Å; E16-G80 PolarHBondContact OE1-N 3.19Å
17V94.3Very high94.3Very high0 Ų047 Ų470%025%0.248CC..EExtended strand (participates in β ladder)trans-100.4128.7171.2-170.50000108.7L38 Y39 L41 L94 W96V17-L38 HydrophobicContact CG1-CD1 4.11Å; V17-L38 PolarHBondContact O-N 3.2Å; V17-Y39 HydrophobicContact CB-CE1 4.48Å; V17-Y39 HydrophobicContact CB-CE2 4.47Å; V17-Y39 HydrophobicContact CG2-CD2 4.28Å; V17-Y39 HydrophobicContact CG2-CE2 3.83Å; V17-Y39 PolarHBondContact N-O 2.96Å; V17-L41 HydrophobicContact CG2-CD1 4.12Å; V17-L41 HydrophobicContact CG2-CD2 3.99Å; V17-L41 HydrophobicContact CG2-CG 3.73Å; V17-L94 HydrophobicContact CG1-CD1 4.07Å; V17-L94 HydrophobicContact CG1-CD2 4.19Å; V17-W96 HydrophobicContact CG2-CH2 3.96Å; V17-W96 HydrophobicContact CG2-CZ2 4.33Å
18W95.2Very high94.3Very high1 Ų144.9 Ų44.90%0.00424%0.241CC..EExtended strand (participates in β ladder)trans-118.3131.7176-7474.1000108.9E16 W35 R36 Y37 G68 A69 R71 G80 W82 W88E16-W18 PolarHBondContact OE2-NE1 3.1Å; W18-W35 HydrophobicContact CB-CE3 3.99Å; W18-W35 HydrophobicContact CB-CZ3 3.8Å; W18-R36 CarbonylContact C-O 3.59Å; W18-R36 WeakPolarHBondContact CA-O 3.26Å; W18-R36 VanDerWaalsContact CE3-C 3.5Å; W18-Y37 VanDerWaalsContact CE3-N 3.3Å; W18-Y37 HydrophobicContact CZ2-CD2 4.4Å; W18-G68 CarbonylContact O-C 3.49Å; W18-G68 WeakPolarHBondContact O-CA 3.24Å; W18-A69 PolarHBondContact N-O 2.98Å; W18-A69 PolarHBondContact O-N 3.44Å; W18-R71 VanDerWaalsContact CZ2-NH1 3.26Å; W18-G80 VanDerWaalsContact CH2-O 3.3Å; W18-G80 WeakPolarHBondContact CH2-O 3.48Å; W18-W82 HydrophobicContact CE3-CH2 4.41Å; W18-W82 HydrophobicContact CE3-CZ2 4.38Å; W18-W82 HydrophobicContact CH2-CD2 4.05Å; W18-W82 AromaticContact CH2-CE2 3.89Å; W18-W82 HydrophobicContact CH2-CE3 4.46Å; W18-W82 HydrophobicContact CH2-CG 4.47Å; W18-W82 HydrophobicContact CH2-CZ2 4.23Å; W18-W82 HydrophobicContact CZ3-CD2 4.12Å; W18-W82 AromaticContact CZ3-CE2 3.61Å; W18-W82 HydrophobicContact CZ3-CE3 4.39Å; W18-W82 AromaticContact CZ3-CH2 3.81Å; W18-W82 HydrophobicContact CZ3-CH2 3.81Å; W18-W82 AromaticContact CZ3-CZ2 3.49Å; W18-W82 HydrophobicContact CZ3-CZ2 3.49Å; W18-W82 VanDerWaalsContact CZ3-CZ2 3.49Å; W18-W82 HydrophobicContact CZ3-CZ3 4.24Å; W18-W88 HydrophobicContact CB-CH2 4.27Å; W18-W88 HydrophobicContact CB-CZ3 3.82Å; W18-W88 AromaticContact CD1-CH2 3.95Å; W18-W88 AromaticContact CD1-CZ3 3.87Å; W18-W88 AromaticContact CD2-CH2 3.76Å; W18-W88 HydrophobicContact CD2-CH2 3.76Å; W18-W88 HydrophobicContact CD2-CZ3 4.21Å; W18-W88 HydrophobicContact CE3-CH2 4.28Å; W18-W88 AromaticContact CG-CH2 3.73Å; W18-W88 HydrophobicContact CG-CH2 3.73Å; W18-W88 AromaticContact CG-CZ3 3.67Å; W18-W88 HydrophobicContact CG-CZ3 3.67Å
19G94.7Very high94.2Very high0 Ų051.7 Ų51.70%027%0.272CS..EExtended strand (participates in β ladder)trans-102.7151.9178.300000111.5W35 R36 W65 L67G19-W35 WeakPolarHBondContact O-CA 3.47Å; G19-R36 PolarHBondContact N-O 2.88Å; G19-R36 PolarHBondContact O-N 3.3Å; G19-W65 WeakPolarHBondContact O-CZ3 3.39Å; G19-L67 CarbonylContact C-O 3.59Å; G19-L67 WeakPolarHBondContact CA-O 3.49Å
20Y95.5Very high94.4Very high4 Ų447.4 Ų47.42%0.01625%0.254CS..EExtended strand (participates in β ladder)trans-123.2139.5169-177.5-95.6000111.1E22 D34 W35 L67 I224 Q227 V231Y20-E22 HydrophobicContact CE1-CG 3.47Å; Y20-E22 VanDerWaalsContact CE1-CG 3.47Å; Y20-E22 WeakPolarHBondContact OH-CG 3.44Å; Y20-E22 PolarHBondContact OH-OE1 3.04Å; Y20-D34 WeakPolarHBondContact CA-O 3.16Å; Y20-D34 WeakPolarHBondContact CD2-O 3.35Å; Y20-W35 AromaticContact CD2-CD1 3.29Å; Y20-W35 AromaticContact CD2-CD2 3.93Å; Y20-W35 HydrophobicContact CD2-CD2 3.93Å; Y20-W35 AromaticContact CD2-CE2 3.64Å; Y20-W35 AromaticContact CD2-CG 3.72Å; Y20-W35 HydrophobicContact CD2-CG 3.72Å; Y20-W35 HydrophobicContact CD2-CZ2 4.4Å; Y20-W35 AromaticContact CD2-NE1 3.21Å; Y20-W35 AromaticContact CE2-CD1 3.65Å; Y20-W35 HydrophobicContact CE2-CG 4.44Å; Y20-W35 AromaticContact CE2-NE1 3.63Å; Y20-L67 HydrophobicContact CD1-CD2 3.75Å; Y20-L67 HydrophobicContact CG-CD2 4.32Å; Y20-L67 PolarHBondContact N-O 3.02Å; Y20-I224 WeakPolarHBondContact OH-CD1 3.19Å; Y20-Q227 HydrophobicContact CD1-CB 3.81Å; Y20-Q227 HydrophobicContact CD1-CG 4.18Å; Y20-Q227 HydrophobicContact CD2-CB 4.23Å; Y20-Q227 HydrophobicContact CD2-CG 4.02Å; Y20-Q227 HydrophobicContact CE1-CB 3.44Å; Y20-Q227 VanDerWaalsContact CE1-CB 3.44Å; Y20-Q227 HydrophobicContact CE1-CG 4.23Å; Y20-Q227 HydrophobicContact CE2-CB 3.92Å; Y20-Q227 HydrophobicContact CE2-CG 4.08Å; Y20-Q227 HydrophobicContact CG-CB 4.12Å; Y20-Q227 HydrophobicContact CG-CG 4Å; Y20-Q227 VanDerWaalsContact CZ-CB 3.46Å; Y20-V231 HydrophobicContact CD1-CG2 3.87Å; Y20-V231 HydrophobicContact CE1-CG2 3.81Å
21E93.4Very high94.3Very high32 Ų3246 Ų4615%0.1524%0.243CC..EExtended strand (participates in β ladder)trans-145.8158.2170.171.3-178-179.100110.7T23 G33 D34 R64 W65E21-T23 HydrophobicContact CG-CG2 4Å; E21-G33 CarbonylContact O-C 3.54Å; E21-G33 WeakPolarHBondContact O-CA 3.47Å; E21-D34 HydrophobicContact CG-CB 4.46Å; E21-D34 PolarHBondContact N-O 3.09Å; E21-D34 VanDerWaalsContact N-O 3.08Å; E21-D34 PolarHBondContact O-N 3.43Å; E21-R64 VanDerWaalsContact CD-NH1 3.26Å; E21-R64 IonicContact OE1-CZ 2.71Å; E21-R64 IonicContact OE1-NH1 2.8Å; E21-R64 PolarHBondContact OE1-NH1 3.35Å; E21-R64 IonicContact OE1-NH2 3.98Å; E21-R64 PolarHBondContact OE1-NH2 3.06Å; E21-R64 IonicContact OE2-CZ 2.72Å; E21-R64 VanDerWaalsContact OE2-CZ 3.3Å; E21-R64 IonicContact OE2-NH1 3.72Å; E21-R64 PolarHBondContact OE2-NH1 2.78Å; E21-R64 IonicContact OE2-NH2 3.75Å; E21-W65 HydrophobicContact CB-CE3 4.02Å; E21-W65 HydrophobicContact CB-CZ3 3.89Å; E21-W65 HydrophobicContact CG-CE3 4.04Å; E21-W65 HydrophobicContact CG-CH2 3.66Å; E21-W65 HydrophobicContact CG-CZ2 4.35Å; E21-W65 HydrophobicContact CG-CZ3 3.5Å
22E94.6Very high94.2Very high26 Ų2643.5 Ų43.512%0.12123%0.232CC..EExtended strand (participates in β ladder)trans-118127.6170.6-60.3-174.5173.900109.4Y20 Q32 P221 S228 V231 Y232Y20-E22 HydrophobicContact CE1-CG 3.47Å; Y20-E22 VanDerWaalsContact CE1-CG 3.47Å; Y20-E22 WeakPolarHBondContact OH-CG 3.44Å; Y20-E22 PolarHBondContact OH-OE1 3.04Å; E22-Q32 WeakPolarHBondContact CA-O 3.07Å; E22-P221 HydrophobicContact CB-CG 4.11Å; E22-P221 VanDerWaalsContact CD-CG 3.45Å; E22-P221 HydrophobicContact CG-CB 4.42Å; E22-P221 HydrophobicContact CG-CG 3.81Å; E22-P221 WeakPolarHBondContact OE2-CB 3.42Å; E22-P221 WeakPolarHBondContact OE2-CG 3.49Å; E22-S228 WeakPolarHBondContact OE1-CA 3.35Å; E22-S228 WeakPolarHBondContact OE1-CB 3.12Å; E22-S228 PolarHBondContact OE1-OG 3.25Å; E22-V231 HydrophobicContact CG-CG2 4.45Å; E22-Y232 WeakPolarHBondContact OE2-CE2 3.36Å; E22-Y232 PolarHBondContact OE2-OH 2.75Å; E22-Y232 VanDerWaalsContact OE2-OH 3.06Å
23T93Very high94.1Very high65 Ų6540 Ų4040%0.39922%0.224SC..EExtended strand (participates in β ladder)trans-131.2163.3-174.962.70000111.3E21 W31 Q32E21-T23 HydrophobicContact CG-CG2 4Å; T23-W31 WeakPolarHBondContact O-CA 3.44Å; T23-Q32 PolarHBondContact N-O 2.68Å; T23-Q32 PolarHBondContact O-N 3.11Å
24G93.4Very high93.8Very high48 Ų4843.2 Ų43.250%0.49524%0.242SC..SBendtrans99.7-171.8-175.100000112.9
25E92.8Very high93.6Very high135 Ų13545.5 Ų45.563%0.63125%0.25SS*.SBendtrans-85.8121.7-177-73.3-73.7161.800110.2S28 S30 W31E25-S28 WeakPolarHBondContact CB-OG 3.45Å; E25-S28 WeakPolarHBondContact O-CB 3.49Å; E25-S28 PolarHBondContact O-N 2.95Å; E25-S28 VanDerWaalsContact O-N 3.11Å; E25-S28 PolarHBondContact O-OG 2.85Å; E25-S30 PolarHBondContact N-OG 2.81Å; E25-S30 VanDerWaalsContact N-OG 3.1Å; E25-W31 WeakPolarHBondContact O-CB 3.13Å
26P91.8Very high93.5Very high46 Ų4651.4 Ų51.430%0.29927%0.272SS..THydrogen-bonded Turntrans-53.9140.2-179.8-28.236000113.8S28 W31 L124P26-S28 PolarHBondContact O-N 2.77Å; P26-W31 HydrophobicContact CB-CD2 4.33Å; P26-W31 HydrophobicContact CB-CE3 4.4Å; P26-W31 HydrophobicContact CB-CH2 3.97Å; P26-W31 HydrophobicContact CB-CZ2 3.97Å; P26-W31 HydrophobicContact CB-CZ3 4.19Å; P26-W31 HydrophobicContact CG-CZ2 4.46Å; P26-L124 HydrophobicContact CB-CD2 3.29Å; P26-L124 HydrophobicContact CG-CD2 3.61Å
27Y90.1Very high93.5Very high71 Ų7154 Ų5428%0.27828%0.283SS..THydrogen-bonded Turntrans54.726-174.4-62.1-84.7000114.8W31 P125 Y181 P222Y27-W31 AromaticContact CD1-CZ3 3.93Å; Y27-W31 HydrophobicContact CD1-CZ3 3.93Å; Y27-W31 HydrophobicContact CD2-CH2 4.07Å; Y27-W31 AromaticContact CD2-CZ3 3.7Å; Y27-W31 HydrophobicContact CD2-CZ3 3.7Å; Y27-W31 HydrophobicContact CE1-CZ3 4.08Å; Y27-W31 AromaticContact CE2-CH2 3.91Å; Y27-W31 HydrophobicContact CE2-CH2 3.91Å; Y27-W31 AromaticContact CE2-CZ3 3.89Å; Y27-W31 HydrophobicContact CE2-CZ3 3.89Å; Y27-W31 HydrophobicContact CG-CE3 4.48Å; Y27-W31 AromaticContact CG-CZ3 3.73Å; Y27-W31 HydrophobicContact CG-CZ3 3.73Å; Y27-P125 HydrophobicContact CD2-CG 3.85Å; Y27-P125 HydrophobicContact CE2-CG 4.06Å; Y27-Y181 HydrophobicContact CD1-CD1 4.49Å; Y27-Y181 AromaticContact CE1-CD1 3.79Å; Y27-Y181 HydrophobicContact CE1-CD1 3.79Å; Y27-Y181 AromaticContact CZ-CD1 3.84Å; Y27-Y181 PolarHBondContact OH-O 2.83Å; Y27-P222 HydrophobicContact CE1-CG 4.12Å
28S91.6Very high93.4Very high44 Ų4454.2 Ų54.231%0.30828%0.284SS..SBendtrans-115171.317486.10000112.4E25 P26 S30 W31E25-S28 WeakPolarHBondContact CB-OG 3.45Å; E25-S28 WeakPolarHBondContact O-CB 3.49Å; E25-S28 PolarHBondContact O-N 2.95Å; E25-S28 VanDerWaalsContact O-N 3.11Å; E25-S28 PolarHBondContact O-OG 2.85Å; P26-S28 PolarHBondContact O-N 2.77Å; S28-S30 PolarHBondContact O-N 3.25Å; S28-S30 PolarHBondContact OG-N 3.48Å; S28-S30 VanDerWaalsContact OG-N 3.11Å; S28-S30 PolarHBondContact OG-OG 3.12Å; S28-W31 WeakPolarHBondContact O-CB 3.32Å; S28-W31 PolarHBondContact O-N 2.65Å
29E90.8Very high93.3Very high144 Ų14456.4 Ų56.467%0.67329%0.292SS*.THydrogen-bonded Turntrans-67.9-16.7174-68.9-61125.200113.8W31 K220E29-W31 VanDerWaalsContact C-N 3.33Å; E29-K220 IonicContact OE1-NZ 3.57Å; E29-K220 PolarHBondContact OE1-NZ 2.74Å; E29-K220 IonicContact OE2-NZ 3.72Å; E29-K220 PolarHBondContact OE2-NZ 2.87Å
30S94.3Very high93.3Very high58 Ų5857.6 Ų57.641%0.40630%0.3SS..THydrogen-bonded Turntrans-84.5-8.9174.870.30000113E25 S28 Q32E25-S30 PolarHBondContact N-OG 2.81Å; E25-S30 VanDerWaalsContact N-OG 3.1Å; S28-S30 PolarHBondContact O-N 3.25Å; S28-S30 PolarHBondContact OG-N 3.48Å; S28-S30 VanDerWaalsContact OG-N 3.11Å; S28-S30 PolarHBondContact OG-OG 3.12Å; S30-Q32 PolarHBondContact O-N 3.37Å
31W93.4Very high93.1Very high8 Ų859.1 Ų59.13%0.0331%0.309CS..  trans-74.7112.4178.4-156.37.9000110.9T23 E25 P26 Y27 S28 E29 P221 P222 Y232T23-W31 WeakPolarHBondContact O-CA 3.44Å; E25-W31 WeakPolarHBondContact O-CB 3.13Å; P26-W31 HydrophobicContact CB-CD2 4.33Å; P26-W31 HydrophobicContact CB-CE3 4.4Å; P26-W31 HydrophobicContact CB-CH2 3.97Å; P26-W31 HydrophobicContact CB-CZ2 3.97Å; P26-W31 HydrophobicContact CB-CZ3 4.19Å; P26-W31 HydrophobicContact CG-CZ2 4.46Å; Y27-W31 AromaticContact CD1-CZ3 3.93Å; Y27-W31 HydrophobicContact CD1-CZ3 3.93Å; Y27-W31 HydrophobicContact CD2-CH2 4.07Å; Y27-W31 AromaticContact CD2-CZ3 3.7Å; Y27-W31 HydrophobicContact CD2-CZ3 3.7Å; Y27-W31 HydrophobicContact CE1-CZ3 4.08Å; Y27-W31 AromaticContact CE2-CH2 3.91Å; Y27-W31 HydrophobicContact CE2-CH2 3.91Å; Y27-W31 AromaticContact CE2-CZ3 3.89Å; Y27-W31 HydrophobicContact CE2-CZ3 3.89Å; Y27-W31 HydrophobicContact CG-CE3 4.48Å; Y27-W31 AromaticContact CG-CZ3 3.73Å; Y27-W31 HydrophobicContact CG-CZ3 3.73Å; S28-W31 WeakPolarHBondContact O-CB 3.32Å; S28-W31 PolarHBondContact O-N 2.65Å; E29-W31 VanDerWaalsContact C-N 3.33Å; W31-P221 HydrophobicContact CB-CB 4.47Å; W31-P221 HydrophobicContact CD2-CB 3.33Å; W31-P221 HydrophobicContact CD2-CG 4.34Å; W31-P221 HydrophobicContact CE3-CB 3.8Å; W31-P221 VanDerWaalsContact CE3-O 3.23Å; W31-P221 HydrophobicContact CG-CB 3.6Å; W31-P221 HydrophobicContact CG-CG 4.11Å; W31-P221 HydrophobicContact CZ2-CB 4.03Å; W31-P221 HydrophobicContact CZ3-CB 4.4Å; W31-P222 HydrophobicContact CH2-CB 3.96Å; W31-P222 HydrophobicContact CH2-CG 3.93Å; W31-P222 HydrophobicContact CZ2-CB 4.45Å; W31-P222 HydrophobicContact CZ3-CB 4.44Å; W31-P222 VanDerWaalsContact CZ3-CD 3.45Å; W31-P222 HydrophobicContact CZ3-CG 4.07Å; W31-Y232 AromaticContact CZ2-CE2 3.83Å; W31-Y232 HydrophobicContact CZ2-CE2 3.83Å; W31-Y232 AromaticContact CZ2-CZ 3.59Å; W31-Y232 WeakPolarHBondContact CZ2-OH 3.31Å; W31-Y232 PolarHBondContact NE1-OH 3.15Å
32Q95.2Very high93.2Very high123 Ų12359.3 Ų59.358%0.57531%0.312SS*.EExtended strand (participates in β ladder)trans-138.8139.4-173.4-62.5-17821.600110.7E22 T23 S30E22-Q32 WeakPolarHBondContact CA-O 3.07Å; T23-Q32 PolarHBondContact N-O 2.68Å; T23-Q32 PolarHBondContact O-N 3.11Å; S30-Q32 PolarHBondContact O-N 3.37Å
33G94.1Very high93.3Very high29 Ų2963.3 Ų63.330%0.29933%0.329SS..EExtended strand (participates in β ladder)trans-87.8134.9168.800000110.3E21E21-G33 CarbonylContact O-C 3.54Å; E21-G33 WeakPolarHBondContact O-CA 3.47Å
34D93Very high93.5Very high68 Ų6864.8 Ų64.836%0.36433%0.334SS..EExtended strand (participates in β ladder)trans-119.1132.5176-170.826.7000110Y20 E21 W65Y20-D34 WeakPolarHBondContact CA-O 3.16Å; Y20-D34 WeakPolarHBondContact CD2-O 3.35Å; E21-D34 HydrophobicContact CG-CB 4.46Å; E21-D34 PolarHBondContact N-O 3.09Å; E21-D34 VanDerWaalsContact N-O 3.08Å; E21-D34 PolarHBondContact O-N 3.43Å; D34-W65 HydrophobicContact CB-CH2 4.41Å
35W92.7Very high93.7Very high54 Ų5464.1 Ų64.121%0.20532%0.318CS..EExtended strand (participates in β ladder)trans-111.1127171.6-94.8101.6000107.9W18 G19 Y20 A69 W82 W88 Q227W18-W35 HydrophobicContact CB-CE3 3.99Å; W18-W35 HydrophobicContact CB-CZ3 3.8Å; G19-W35 WeakPolarHBondContact O-CA 3.47Å; Y20-W35 AromaticContact CD2-CD1 3.29Å; Y20-W35 AromaticContact CD2-CD2 3.93Å; Y20-W35 HydrophobicContact CD2-CD2 3.93Å; Y20-W35 AromaticContact CD2-CE2 3.64Å; Y20-W35 AromaticContact CD2-CG 3.72Å; Y20-W35 HydrophobicContact CD2-CG 3.72Å; Y20-W35 HydrophobicContact CD2-CZ2 4.4Å; Y20-W35 AromaticContact CD2-NE1 3.21Å; Y20-W35 AromaticContact CE2-CD1 3.65Å; Y20-W35 HydrophobicContact CE2-CG 4.44Å; Y20-W35 AromaticContact CE2-NE1 3.63Å; W35-A69 HydrophobicContact CH2-CB 4.01Å; W35-A69 HydrophobicContact CZ3-CB 4.28Å; W35-W82 HydrophobicContact CB-CH2 3.57Å; W35-W82 HydrophobicContact CB-CZ2 4.09Å; W35-W82 HydrophobicContact CG-CH2 4.44Å; W35-W82 WeakPolarHBondContact O-CZ2 3.36Å; W35-W88 HydrophobicContact CZ3-CZ3 4.42Å; W35-Q227 HydrophobicContact CZ2-CG 3.67Å
36R94.1Very high93.9Very high124 Ų12461.3 Ų61.347%0.46831%0.312SS..EExtended strand (participates in β ladder)trans-137.1133.9-173.2-164.8174.5175.3168.1-4.7112.4W18 G19 L38 W65W18-R36 CarbonylContact C-O 3.59Å; W18-R36 WeakPolarHBondContact CA-O 3.26Å; W18-R36 VanDerWaalsContact CE3-C 3.5Å; G19-R36 PolarHBondContact N-O 2.88Å; G19-R36 PolarHBondContact O-N 3.3Å; R36-L38 HydrophobicContact CB-CD2 4.48Å; R36-L38 PolarHBondContact O-N 2.99Å; R36-W65 HydrophobicContact CB-CH2 3.43Å; R36-W65 VanDerWaalsContact CB-CH2 3.43Å; R36-W65 HydrophobicContact CB-CZ2 3.71Å; R36-W65 HydrophobicContact CB-CZ3 4.05Å; R36-W65 HydrophobicContact CG-CH2 4.39Å; R36-W65 HydrophobicContact CG-CZ2 4.24Å
37Y95.1Very high94.1Very high55 Ų5560.6 Ų60.622%0.21631%0.306CS..EExtended strand (participates in β ladder)trans-61.9125.2163.9168.2-96.9000109.2E16 W18 Y39 S40 D79 G80E16-Y37 HydrophobicContact CB-CD2 4.23Å; E16-Y37 HydrophobicContact CB-CE2 3.99Å; E16-Y37 HydrophobicContact CG-CD2 4.44Å; E16-Y37 HydrophobicContact CG-CE2 3.95Å; W18-Y37 VanDerWaalsContact CE3-N 3.3Å; W18-Y37 HydrophobicContact CZ2-CD2 4.4Å; Y37-Y39 WeakPolarHBondContact OH-CA 3.38Å; Y37-S40 PolarHBondContact OH-N 2.8Å; Y37-S40 PolarHBondContact OH-OG 3.04Å; Y37-D79 HydrophobicContact CE1-CB 4.17Å; Y37-D79 HydrophobicContact CE2-CB 4.01Å; Y37-G80 VanDerWaalsContact CG-CA 3.45Å
38L93.1Very high94.4Very high4 Ų461.8 Ų61.82%0.02132%0.316CS..EExtended strand (participates in β ladder)trans-95.3-68.7177.6-51.5-175.4000109.6V17 R36 F62 W65 L94V17-L38 HydrophobicContact CG1-CD1 4.11Å; V17-L38 PolarHBondContact O-N 3.2Å; R36-L38 HydrophobicContact CB-CD2 4.48Å; R36-L38 PolarHBondContact O-N 2.99Å; L38-F62 HydrophobicContact CB-CD1 4.28Å; L38-F62 HydrophobicContact CB-CD2 4.5Å; L38-F62 HydrophobicContact CB-CG 4.24Å; L38-F62 HydrophobicContact CD2-CD1 3.81Å; L38-F62 HydrophobicContact CD2-CE1 4.24Å; L38-F62 HydrophobicContact CD2-CG 4.44Å; L38-F62 WeakPolarHBondContact O-CE2 3.42Å; L38-F62 WeakPolarHBondContact O-CZ 3.3Å; L38-W65 HydrophobicContact CD1-CB 3.9Å; L38-W65 HydrophobicContact CD1-CG 4.12Å; L38-W65 HydrophobicContact CD2-CB 4.43Å; L38-W65 HydrophobicContact CD2-CD2 3.82Å; L38-W65 HydrophobicContact CD2-CG 3.76Å; L38-L94 HydrophobicContact CD1-CD1 4.12Å
39Y92.9Very high94.6Very high47 Ų4760.2 Ų60.218%0.18431%0.307CS..EExtended strand (participates in β ladder)trans-161.3164.9-177.755.8-87.8000111.6V17 Y37 L41 A58 F62V17-Y39 HydrophobicContact CB-CE1 4.48Å; V17-Y39 HydrophobicContact CB-CE2 4.47Å; V17-Y39 HydrophobicContact CG2-CD2 4.28Å; V17-Y39 HydrophobicContact CG2-CE2 3.83Å; V17-Y39 PolarHBondContact N-O 2.96Å; Y37-Y39 WeakPolarHBondContact OH-CA 3.38Å; Y39-L41 HydrophobicContact CE2-CD2 4.06Å; Y39-A58 HydrophobicContact CE1-CB 4.29Å; Y39-F62 HydrophobicContact CD1-CD2 4.04Å
40S93.8Very high94.9Very high25 Ų2556 Ų5618%0.17529%0.293CS..EExtended strand (participates in β ladder)trans-94.4125.1176.2-53.60000110.2I15 Y37 T42 D79I15-S40 CarbonylContact O-C 3.52Å; I15-S40 WeakPolarHBondContact O-CA 3.3Å; Y37-S40 PolarHBondContact OH-N 2.8Å; Y37-S40 PolarHBondContact OH-OG 3.04Å; S40-T42 VanDerWaalsContact C-N 3.31Å; S40-D79 VanDerWaalsContact OG-CG 3.28Å; S40-D79 PolarHBondContact OG-OD1 2.51Å
41L93.1Very high94.9Very high36 Ų3654.4 Ų54.419%0.18828%0.279CS..EExtended strand (participates in β ladder)trans-65-38.6171.1-70.8175000111.2I15 V17 Y39 F51 F53 V70 W96I15-L41 HydrophobicContact CB-CB 4.43Å; I15-L41 HydrophobicContact CG2-CB 4.24Å; I15-L41 HydrophobicContact CG2-CD1 3.97Å; I15-L41 PolarHBondContact O-N 2.89Å; V17-L41 HydrophobicContact CG2-CD1 4.12Å; V17-L41 HydrophobicContact CG2-CD2 3.99Å; V17-L41 HydrophobicContact CG2-CG 3.73Å; Y39-L41 HydrophobicContact CE2-CD2 4.06Å; L41-F51 HydrophobicContact CB-CE1 3.81Å; L41-F51 HydrophobicContact CB-CZ 4.3Å; L41-F51 HydrophobicContact CD1-CE1 4.26Å; L41-F53 HydrophobicContact CD1-CD1 3.91Å; L41-F53 HydrophobicContact CD1-CE1 3.67Å; L41-F53 HydrophobicContact CD1-CG 4.44Å; L41-F53 HydrophobicContact CD1-CZ 4.02Å; L41-F53 HydrophobicContact CD2-CD1 4.48Å; L41-F53 HydrophobicContact CD2-CD2 3.92Å; L41-F53 HydrophobicContact CD2-CE1 4.49Å; L41-F53 HydrophobicContact CD2-CE2 3.96Å; L41-F53 HydrophobicContact CD2-CG 4.21Å; L41-F53 HydrophobicContact CD2-CZ 4.24Å; L41-V70 HydrophobicContact CD1-CG1 4.39Å; L41-W96 HydrophobicContact CD2-CH2 3.73Å; L41-W96 HydrophobicContact CD2-CZ3 4.14Å
42T95.1Very high94.9Very high35 Ų3563.3 Ų63.322%0.21532%0.319CS..EExtended strand (participates in β ladder)trans-157.1157.8173.5-171.80000110.4I15 S40 H45 F51I15-T42 HydrophobicContact CB-CG2 3.84Å; I15-T42 HydrophobicContact CD1-CG2 3.65Å; I15-T42 HydrophobicContact CG1-CG2 3.74Å; I15-T42 PolarHBondContact N-O 3.34Å; I15-T42 PolarHBondContact O-N 3.29Å; S40-T42 VanDerWaalsContact C-N 3.31Å; T42-H45 HydrophobicContact CG2-CB 3.71Å; T42-F51 HydrophobicContact CG2-CD2 3.84Å; T42-F51 HydrophobicContact CG2-CE1 4.18Å; T42-F51 HydrophobicContact CG2-CE2 3.42Å; T42-F51 VanDerWaalsContact CG2-CE2 3.42Å; T42-F51 HydrophobicContact CG2-CG 4.39Å; T42-F51 HydrophobicContact CG2-CZ 3.61Å
43K96.3Very high94.7Very high111 Ų11160.9 Ų60.948%0.48331%0.306SS..EExtended strand (participates in β ladder)trans-127153.7178-61.5-179.3-178.7-173.10109.4H45 D79K43-H45 PolarHBondContact O-N 3.49Å; K43-H45 VanDerWaalsContact O-N 3.08Å; K43-D79 WeakPolarHBondContact CE-OD1 3.19Å; K43-D79 WeakPolarHBondContact CE-OD2 3.42Å; K43-D79 IonicContact NZ-OD1 3.45Å; K43-D79 IonicContact NZ-OD2 2.61Å; K43-D79 PolarHBondContact NZ-OD2 3.47Å
44D96.8Very high94.2Very high95 Ų9564.9 Ų64.951%0.50832%0.324SS..EExtended strand (participates in β ladder)trans53.629.6177.5-69.4-60.4000113.8K12 N14 S75K12-D44 HydrophobicContact CD-CB 4.13Å; N14-D44 PolarHBondContact OD1-N 2.89Å; D44-S75 VanDerWaalsContact CA-OG 3.31Å; D44-S75 WeakPolarHBondContact CA-OG 3.41Å; D44-S75 PolarHBondContact N-OG 3.22Å; D44-S75 WeakPolarHBondContact OD1-CB 3.3Å
45H97.2Very high93.7Very high35 Ų3563.7 Ų63.716%0.16232%0.32CS..EExtended strand (participates in β ladder)trans-76.7135.7-177-176.872.3000110.2K12 V13 T42 K43 N47 S50 F51K12-H45 CarbonylContact C-O 3.56Å; K12-H45 VanDerWaalsContact CA-O 3.28Å; K12-H45 WeakPolarHBondContact CA-O 3.42Å; V13-H45 HydrophobicContact CG2-CB 4.38Å; V13-H45 WeakPolarHBondContact CG2-O 3.47Å; V13-H45 PolarHBondContact N-O 2.89Å; V13-H45 PolarHBondContact O-N 2.93Å; T42-H45 HydrophobicContact CG2-CB 3.71Å; K43-H45 PolarHBondContact O-N 3.49Å; K43-H45 VanDerWaalsContact O-N 3.08Å; H45-N47 PolarHBondContact O-N 3.46Å; H45-S50 PolarHBondContact NE2-O 3.31Å; H45-S50 VanDerWaalsContact NE2-O 3.12Å; H45-F51 AromaticContact CE1-CD2 3.92Å
46P97.6Very high92.9Very high76 Ų7668.7 Ų68.749%0.49434%0.343SS..EExtended strand (participates in β ladder)trans-56133.1175.9-24.934.3000111.9N48P46-N48 PolarHBondContact O-N 3.11Å
47N96.8Very high92.1Very high31 Ų3166.8 Ų66.817%0.16634%0.342CS..  trans-75.567.9178.6-169.315.2000111.8W3 T5 V8 S10 E11 V13 H45W3-N47 PolarHBondContact NE1-OD1 3.46Å; T5-N47 WeakPolarHBondContact CG2-O 3.29Å; T5-N47 PolarHBondContact O-ND2 3.31Å; V8-N47 PolarHBondContact O-ND2 2.88Å; S10-N47 WeakPolarHBondContact O-CB 3.21Å; S10-N47 PolarHBondContact O-ND2 3.13Å; E11-N47 PolarHBondContact O-N 2.84Å; V13-N47 HydrophobicContact CG1-CB 3.98Å; H45-N47 PolarHBondContact O-N 3.46Å
48N96.1Very high91.4Very high95 Ų9564.6 Ų64.651%0.50834%0.335SS..SBendtrans-98.86.7-179.868.911.8000113.4P46 S50P46-N48 PolarHBondContact O-N 3.11Å; N48-S50 VanDerWaalsContact C-N 3.34Å; N48-S50 PolarHBondContact O-N 2.68Å; N48-S50 PolarHBondContact OD1-N 2.98Å; N48-S50 VanDerWaalsContact OD1-N 3.1Å; N48-S50 PolarHBondContact OD1-O 3.03Å
49G95.6Very high90.8Very high11 Ų1172.5 Ų72.511%0.11337%0.372CS..SBendtrans79.97175.900000115.2T2 W3 T5T2-G49 CarbonylContact C-O 3.45Å; T2-G49 WeakPolarHBondContact CA-O 3.44Å; W3-G49 PolarHBondContact N-O 3.5Å; W3-G49 WeakPolarHBondContact O-CA 3.4Å; T5-G49 VanDerWaalsContact CG2-CA 3.49Å; T5-G49 VanDerWaalsContact CG2-N 3.28Å
50S96.1Very high90.1Very high55 Ų5573.2 Ų73.239%0.38539%0.394SS..BIsolated β-bridgetrans-147.5146.9178.770.70000113.9W3 H45 N48W3-S50 VanDerWaalsContact CH2-C 3.49Å; W3-S50 WeakPolarHBondContact CH2-O 3.49Å; H45-S50 PolarHBondContact NE2-O 3.31Å; H45-S50 VanDerWaalsContact NE2-O 3.12Å; N48-S50 VanDerWaalsContact C-N 3.34Å; N48-S50 PolarHBondContact O-N 2.68Å; N48-S50 PolarHBondContact OD1-N 2.98Å; N48-S50 VanDerWaalsContact OD1-N 3.1Å; N48-S50 PolarHBondContact OD1-O 3.03Å
51F95.4Very high89.4Confident25 Ų2578.5 Ų78.511%0.1142%0.42CS..  trans-148.5139.9174-179.9-109.5000110.7M1 W3 I15 L41 T42 H45 F53M1-F51 HydrophobicContact CG-CB 3.83Å; M1-F51 HydrophobicContact CG-CD1 4.28Å; M1-F51 WeakPolarHBondContact CG-O 3.32Å; M1-F51 PolarHBondContact N-O 3.24Å; M1-F51 PolarHBondContact O-N 2.95Å; M1-F51 HydrophobicContact SD-CB 4.17Å; M1-F51 HydrophobicContact SD-CD1 3.93Å; W3-F51 HydrophobicContact CH2-CB 3.98Å; W3-F51 HydrophobicContact CZ3-CB 3.73Å; I15-F51 HydrophobicContact CD1-CB 3.39Å; I15-F51 HydrophobicContact CD1-CD1 3.71Å; I15-F51 HydrophobicContact CD1-CD2 3.96Å; I15-F51 HydrophobicContact CD1-CE1 4.45Å; I15-F51 HydrophobicContact CD1-CG 3.42Å; I15-F51 VanDerWaalsContact CD1-CG 3.42Å; I15-F51 HydrophobicContact CG2-CD1 4.41Å; L41-F51 HydrophobicContact CB-CE1 3.81Å; L41-F51 HydrophobicContact CB-CZ 4.3Å; L41-F51 HydrophobicContact CD1-CE1 4.26Å; T42-F51 HydrophobicContact CG2-CD2 3.84Å; T42-F51 HydrophobicContact CG2-CE1 4.18Å; T42-F51 HydrophobicContact CG2-CE2 3.42Å; T42-F51 VanDerWaalsContact CG2-CE2 3.42Å; T42-F51 HydrophobicContact CG2-CG 4.39Å; T42-F51 HydrophobicContact CG2-CZ 3.61Å; H45-F51 AromaticContact CE1-CD2 3.92Å; F51-F53 HydrophobicContact CD1-CB 4.49Å; F51-F53 AromaticContact CD1-CD1 3.96Å; F51-F53 HydrophobicContact CD1-CD1 3.96Å; F51-F53 HydrophobicContact CE1-CB 3.61Å; F51-F53 AromaticContact CE1-CD1 3.66Å; F51-F53 HydrophobicContact CE1-CD1 3.66Å; F51-F53 AromaticContact CE1-CG 3.96Å; F51-F53 HydrophobicContact CE1-CG 3.96Å; F51-F53 HydrophobicContact CZ-CB 3.89Å
52K93.6Very high89.1Confident196 Ų19679.4 Ų79.485%0.85242%0.422SS*.  trans-127.4133.7176.2-66.4-177.6-179.7179.80107.8
53F89.3Confident88.3Confident71 Ų7180.4 Ų80.431%0.31143%0.431SS..  trans-137.7159.9173.868.2-80.9000109.1L41 F51 P55 W96L41-F53 HydrophobicContact CD1-CD1 3.91Å; L41-F53 HydrophobicContact CD1-CE1 3.67Å; L41-F53 HydrophobicContact CD1-CG 4.44Å; L41-F53 HydrophobicContact CD1-CZ 4.02Å; L41-F53 HydrophobicContact CD2-CD1 4.48Å; L41-F53 HydrophobicContact CD2-CD2 3.92Å; L41-F53 HydrophobicContact CD2-CE1 4.49Å; L41-F53 HydrophobicContact CD2-CE2 3.96Å; L41-F53 HydrophobicContact CD2-CG 4.21Å; L41-F53 HydrophobicContact CD2-CZ 4.24Å; F51-F53 HydrophobicContact CD1-CB 4.49Å; F51-F53 AromaticContact CD1-CD1 3.96Å; F51-F53 HydrophobicContact CD1-CD1 3.96Å; F51-F53 HydrophobicContact CE1-CB 3.61Å; F51-F53 AromaticContact CE1-CD1 3.66Å; F51-F53 HydrophobicContact CE1-CD1 3.66Å; F51-F53 AromaticContact CE1-CG 3.96Å; F51-F53 HydrophobicContact CE1-CG 3.96Å; F51-F53 HydrophobicContact CZ-CB 3.89Å; F53-P55 HydrophobicContact CE2-CG 4.16Å; F53-W96 HydrophobicContact CD2-CZ3 4.28Å; F53-W96 HydrophobicContact CE2-CD2 4.21Å; F53-W96 AromaticContact CE2-CE3 3.62Å; F53-W96 HydrophobicContact CE2-CE3 3.62Å; F53-W96 AromaticContact CE2-CH2 3.63Å; F53-W96 HydrophobicContact CE2-CH2 3.63Å; F53-W96 HydrophobicContact CE2-CZ2 4.25Å; F53-W96 AromaticContact CE2-CZ3 3.29Å; F53-W96 HydrophobicContact CE2-CZ3 3.29Å; F53-W96 HydrophobicContact CZ-CD2 4.31Å; F53-W96 HydrophobicContact CZ-CE3 4.13Å; F53-W96 AromaticContact CZ-CH2 3.69Å; F53-W96 HydrophobicContact CZ-CH2 3.69Å; F53-W96 AromaticContact CZ-CZ2 3.91Å; F53-W96 HydrophobicContact CZ-CZ2 3.91Å; F53-W96 AromaticContact CZ-CZ3 3.83Å; F53-W96 HydrophobicContact CZ-CZ3 3.83Å
54V85.3Confident87.7Confident113 Ų11380.5 Ų80.569%0.68543%0.428SS*.  trans-95122.8168.6-179.20000106.7K56V54-K56 PolarHBondContact O-N 3.13Å
55P81.6Confident87.3Confident43 Ų4376 Ų7628%0.27940%0.404SS..  trans-48.3135.8172.5-33.739.9000112.8F53 W96F53-P55 HydrophobicContact CE2-CG 4.16Å; P55-W96 HydrophobicContact CB-CB 3.85Å; P55-W96 HydrophobicContact CB-CD2 4.42Å; P55-W96 HydrophobicContact CB-CE3 3.81Å; P55-W96 HydrophobicContact CB-CG 4.5Å; P55-W96 HydrophobicContact CG-CB 3.92Å; P55-W96 HydrophobicContact CG-CE3 4.24Å; P55-W96 HydrophobicContact CG-CG 4.47Å
56K76.5Confident86.9Confident159 Ų15976.3 Ų76.369%0.69141%0.406SS*.  trans-128.5149.4174.9-67.3-175.8-179.5-179.30109.4V54 A58 E99V54-K56 PolarHBondContact O-N 3.13Å; K56-A58 PolarHBondContact O-N 3.12Å; K56-E99 WeakPolarHBondContact CA-OE2 3.45Å
57I77.5Confident86.8Confident85 Ų8572.8 Ų72.844%0.43638%0.383SS..PPolyproline II helixtrans-50.6132169.4-59.9165.4000108.8E59 E99 E100I57-E59 PolarHBondContact O-N 2.67Å; I57-E99 HydrophobicContact CG1-CB 3.68Å; I57-E99 HydrophobicContact CG1-CG 4.24Å; I57-E99 PolarHBondContact N-OE2 2.79Å; I57-E100 HydrophobicContact CD1-CB 3.93Å
58A79.8Confident86.6Confident8 Ų871.3 Ų71.37%0.06638%0.375CS..PPolyproline II helixtrans-64.8133.1174.300000110.8Y39 K56 F62 H97Y39-A58 HydrophobicContact CE1-CB 4.29Å; K56-A58 PolarHBondContact O-N 3.12Å; A58-F62 HydrophobicContact CB-CB 3.84Å; A58-H97 HydrophobicContact CB-CB 4.16Å; A58-H97 PolarHBondContact N-O 2.67Å
59E80.1Confident86.6Confident170 Ų17066.9 Ų66.979%0.79435%0.352SS*.PPolyproline II helixtrans-74.9142.1177.2-66.1-177.9-172.600111.3I57 F62I57-E59 PolarHBondContact O-N 2.67Å; E59-F62 VanDerWaalsContact O-CD2 3.26Å; E59-F62 WeakPolarHBondContact O-CD2 3.46Å
60G78.3Confident86.6Confident63 Ų6367 Ų6765%0.64935%0.35SS*.G310 helixtrans63.9-141.4178.300000113.7F62G60-F62 PolarHBondContact O-N 3.17Å
61D80.3Confident86.6Confident135 Ų13564.5 Ų64.572%0.72233%0.332SS*.G310 helixtrans-81.88.5-175.3-63.5-25.3000113.7S63 R64D61-S63 PolarHBondContact O-N 3.44Å; D61-R64 WeakPolarHBondContact O-CD 3.23Å; D61-R64 VanDerWaalsContact O-CG 3.31Å; D61-R64 WeakPolarHBondContact O-CG 3.35Å
62F86.2Confident86.7Confident55 Ų5563.5 Ų63.524%0.24133%0.328CS..G310 helixtrans-74.5-13.7-179-64.3-36.7000113.8L38 Y39 A58 E59 G60 R64 W65 H97L38-F62 HydrophobicContact CB-CD1 4.28Å; L38-F62 HydrophobicContact CB-CD2 4.5Å; L38-F62 HydrophobicContact CB-CG 4.24Å; L38-F62 HydrophobicContact CD2-CD1 3.81Å; L38-F62 HydrophobicContact CD2-CE1 4.24Å; L38-F62 HydrophobicContact CD2-CG 4.44Å; L38-F62 WeakPolarHBondContact O-CE2 3.42Å; L38-F62 WeakPolarHBondContact O-CZ 3.3Å; Y39-F62 HydrophobicContact CD1-CD2 4.04Å; A58-F62 HydrophobicContact CB-CB 3.84Å; E59-F62 VanDerWaalsContact O-CD2 3.26Å; E59-F62 WeakPolarHBondContact O-CD2 3.46Å; G60-F62 PolarHBondContact O-N 3.17Å; F62-R64 PolarHBondContact O-N 2.98Å; F62-W65 PolarHBondContact O-N 3.45Å; F62-H97 PolarHBondContact O-CE1 3.17Å
63S78.9Confident86.9Confident57 Ų5754.2 Ų54.240%0.39929%0.288SS..G310 helixtrans-67.6-9.3175.756.80000114.1D61 L98D61-S63 PolarHBondContact O-N 3.44Å; S63-L98 WeakPolarHBondContact O-CD2 3.41Å
64R82.8Confident87.2Confident113 Ų11351.3 Ų51.343%0.42628%0.276SS..G310 helixtrans-82-12.8175.377.7-166.5179.7100.413.5114.6E21 D61 F62 E66E21-R64 VanDerWaalsContact CD-NH1 3.26Å; E21-R64 IonicContact OE1-CZ 2.71Å; E21-R64 IonicContact OE1-NH1 2.8Å; E21-R64 PolarHBondContact OE1-NH1 3.35Å; E21-R64 IonicContact OE1-NH2 3.98Å; E21-R64 PolarHBondContact OE1-NH2 3.06Å; E21-R64 IonicContact OE2-CZ 2.72Å; E21-R64 VanDerWaalsContact OE2-CZ 3.3Å; E21-R64 IonicContact OE2-NH1 3.72Å; E21-R64 PolarHBondContact OE2-NH1 2.78Å; E21-R64 IonicContact OE2-NH2 3.75Å; D61-R64 WeakPolarHBondContact O-CD 3.23Å; D61-R64 VanDerWaalsContact O-CG 3.31Å; D61-R64 WeakPolarHBondContact O-CG 3.35Å; F62-R64 PolarHBondContact O-N 2.98Å; R64-E66 PolarHBondContact O-N 2.97Å
65W89.1Confident87.8Confident1 Ų147 Ų470%0.00425%0.251CS..  trans-89.892.7-170.8-67.884000112G19 E21 D34 R36 L38 F62 L94 H97G19-W65 WeakPolarHBondContact O-CZ3 3.39Å; E21-W65 HydrophobicContact CB-CE3 4.02Å; E21-W65 HydrophobicContact CB-CZ3 3.89Å; E21-W65 HydrophobicContact CG-CE3 4.04Å; E21-W65 HydrophobicContact CG-CH2 3.66Å; E21-W65 HydrophobicContact CG-CZ2 4.35Å; E21-W65 HydrophobicContact CG-CZ3 3.5Å; D34-W65 HydrophobicContact CB-CH2 4.41Å; R36-W65 HydrophobicContact CB-CH2 3.43Å; R36-W65 VanDerWaalsContact CB-CH2 3.43Å; R36-W65 HydrophobicContact CB-CZ2 3.71Å; R36-W65 HydrophobicContact CB-CZ3 4.05Å; R36-W65 HydrophobicContact CG-CH2 4.39Å; R36-W65 HydrophobicContact CG-CZ2 4.24Å; L38-W65 HydrophobicContact CD1-CB 3.9Å; L38-W65 HydrophobicContact CD1-CG 4.12Å; L38-W65 HydrophobicContact CD2-CB 4.43Å; L38-W65 HydrophobicContact CD2-CD2 3.82Å; L38-W65 HydrophobicContact CD2-CG 3.76Å; F62-W65 PolarHBondContact O-N 3.45Å; W65-L94 WeakPolarHBondContact O-CD1 3.28Å; W65-H97 PolarHBondContact O-CE1 3.11Å; W65-H97 PolarHBondContact O-NE2 2.82Å
66E88.9Confident88.5Confident41 Ų4149.3 Ų49.319%0.19227%0.268CS..  trans-86.9-17.4-167.3-65.8170.5165.500114.1R64 A93 L94 L98 K113 L235 Y239R64-E66 PolarHBondContact O-N 2.97Å; E66-A93 WeakPolarHBondContact O-CA 3.44Å; E66-L94 PolarHBondContact O-N 2.81Å; E66-L98 HydrophobicContact CG-CD1 4.13Å; E66-K113 WeakPolarHBondContact OE1-CE 3.26Å; E66-K113 IonicContact OE1-NZ 3.65Å; E66-K113 PolarHBondContact OE1-NZ 3.16Å; E66-K113 IonicContact OE2-NZ 2.75Å; E66-K113 PolarHBondContact OE2-NZ 2.92Å; E66-L235 HydrophobicContact CB-CD1 4.33Å; E66-Y239 WeakPolarHBondContact CB-OH 3.34Å; E66-Y239 PolarHBondContact OE2-OH 3.42Å
67L93.7Very high89.4Confident2 Ų245.1 Ų45.11%0.0125%0.249CC..EExtended strand (participates in β ladder)trans-112.8144.9173.8-175.959.9000110.1G19 Y20 D91 W230 V231 L235G19-L67 CarbonylContact C-O 3.59Å; G19-L67 WeakPolarHBondContact CA-O 3.49Å; Y20-L67 HydrophobicContact CD1-CD2 3.75Å; Y20-L67 HydrophobicContact CG-CD2 4.32Å; Y20-L67 PolarHBondContact N-O 3.02Å; L67-D91 HydrophobicContact CD1-CB 4.17Å; L67-W230 HydrophobicContact CD1-CB 3.81Å; L67-W230 HydrophobicContact CD1-CD2 3.84Å; L67-W230 HydrophobicContact CD1-CE3 3.62Å; L67-W230 HydrophobicContact CD1-CG 3.95Å; L67-W230 HydrophobicContact CD1-CZ3 4.46Å; L67-W230 HydrophobicContact CD2-CB 3.49Å; L67-W230 VanDerWaalsContact CD2-CB 3.49Å; L67-W230 HydrophobicContact CD2-CG 4.36Å; L67-W230 HydrophobicContact CG-CB 4.33Å; L67-V231 HydrophobicContact CD2-CG2 3.89Å; L67-L235 HydrophobicContact CB-CD1 4.06Å
68G94.4Very high90.3Very high0 Ų045.2 Ų45.20%026%0.255CS..EExtended strand (participates in β ladder)trans-179.7-170.5170.300000113.8W18 H92W18-G68 CarbonylContact O-C 3.49Å; W18-G68 WeakPolarHBondContact O-CA 3.24Å; G68-H92 PolarHBondContact N-O 2.92Å; G68-H92 PolarHBondContact O-CD2 2.83Å; G68-H92 PolarHBondContact O-N 2.91Å
69A95.4Very high90.9Very high2 Ų247.3 Ų47.32%0.01727%0.265CS..EExtended strand (participates in β ladder)trans-141.3159.8178.700000110.8W18 W35 W88W18-A69 PolarHBondContact N-O 2.98Å; W18-A69 PolarHBondContact O-N 3.44Å; W35-A69 HydrophobicContact CH2-CB 4.01Å; W35-A69 HydrophobicContact CZ3-CB 4.28Å; A69-W88 HydrophobicContact CB-CE3 4.06Å; A69-W88 HydrophobicContact CB-CZ3 4.43Å
70V95Very high91.6Very high13 Ų1339.9 Ų39.98%0.07923%0.234CC..EExtended strand (participates in β ladder)trans-100.2129.7171.7-176.70000109.4M1 I15 E16 L41 S89M1-V70 HydrophobicContact CE-CB 4.45Å; M1-V70 HydrophobicContact CE-CG1 3.58Å; M1-V70 HydrophobicContact SD-CG1 3.88Å; I15-V70 HydrophobicContact CG2-CG1 3.62Å; E16-V70 CarbonylContact O-C 3.55Å; E16-V70 WeakPolarHBondContact O-CA 3.41Å; L41-V70 HydrophobicContact CD1-CG1 4.39Å; V70-S89 PolarHBondContact N-OG 2.89Å; V70-S89 PolarHBondContact O-N 2.83Å
71R96.6Very high92.4Very high3 Ų341.6 Ų41.61%0.01122%0.223CC..EExtended strand (participates in β ladder)trans-109.3133.4177.8-172.4176.484.1163.14.7110.9I15 E16 W18 K81 A86 A87 W88I15-R71 CarbonylContact C-O 3.46Å; I15-R71 WeakPolarHBondContact CA-O 3.47Å; E16-R71 HydrophobicContact CB-CB 4.39Å; E16-R71 VanDerWaalsContact CD-NH2 3.34Å; E16-R71 PolarHBondContact N-O 3.17Å; E16-R71 PolarHBondContact O-N 3.03Å; E16-R71 IonicContact OE1-NH2 2.92Å; E16-R71 PolarHBondContact OE1-NH2 3.31Å; E16-R71 IonicContact OE2-CZ 2.72Å; E16-R71 IonicContact OE2-NE 2.68Å; E16-R71 PolarHBondContact OE2-NE 3.18Å; E16-R71 IonicContact OE2-NH2 3.82Å; E16-R71 PolarHBondContact OE2-NH2 3.17Å; W18-R71 VanDerWaalsContact CZ2-NH1 3.26Å; R71-K81 PolarHBondContact NH1-O 3.04Å; R71-K81 PolarHBondContact NH2-O 2.98Å; R71-A86 HydrophobicContact CG-CB 3.65Å; R71-A87 WeakPolarHBondContact CA-O 3.45Å; R71-W88 HydrophobicContact CB-CD2 4.05Å; R71-W88 HydrophobicContact CB-CE3 3.83Å; R71-W88 HydrophobicContact CB-CH2 4.14Å; R71-W88 HydrophobicContact CB-CZ2 4.34Å; R71-W88 HydrophobicContact CB-CZ3 3.87Å; R71-W88 VanDerWaalsContact CD-CE2 3.47Å; R71-W88 VanDerWaalsContact CD-CH2 3.49Å; R71-W88 HydrophobicContact CG-CD2 3.91Å; R71-W88 HydrophobicContact CG-CE3 4.18Å; R71-W88 HydrophobicContact CG-CH2 4.17Å; R71-W88 HydrophobicContact CG-CZ2 3.88Å; R71-W88 HydrophobicContact CG-CZ3 4.3Å
72V97.6Very high93.1Very high4 Ų441.6 Ų41.62%0.02421%0.213CC..EExtended strand (participates in β ladder)trans-110.9118.4169-1750000108.5M1 W3 V8 V13 N14 I15 A86 A87M1-V72 HydrophobicContact CE-CG2 3.61Å; W3-V72 HydrophobicContact CD2-CG1 4.32Å; W3-V72 HydrophobicContact CD2-CG2 4.09Å; W3-V72 HydrophobicContact CE3-CG2 4.18Å; W3-V72 HydrophobicContact CG-CG2 4.38Å; W3-V72 HydrophobicContact CZ2-CG1 4.25Å; V8-V72 HydrophobicContact CG2-CG1 4.45Å; V8-V72 WeakPolarHBondContact CG2-O 3.36Å; V13-V72 HydrophobicContact CB-CG1 3.7Å; V13-V72 HydrophobicContact CG1-CG1 3.91Å; V13-V72 HydrophobicContact CG2-CG1 3.8Å; N14-V72 WeakPolarHBondContact O-CA 3.44Å; I15-V72 HydrophobicContact CG1-CG2 4.4Å; V72-A86 CarbonylContact O-C 3.59Å; V72-A86 WeakPolarHBondContact O-CA 3.16Å; V72-A86 VanDerWaalsContact O-CB 3.32Å; V72-A86 WeakPolarHBondContact O-CB 3.38Å; V72-A87 HydrophobicContact CB-CB 4.41Å; V72-A87 PolarHBondContact N-O 3.48Å; V72-A87 PolarHBondContact O-N 3.28Å
73S97.2Very high93.4Very high0 Ų046.7 Ų46.70%024%0.243CC..EExtended strand (participates in β ladder)trans-135.6161.6-178.757.50000111.3V13 N14 S75V13-S73 CarbonylContact C-O 3.45Å; V13-S73 WeakPolarHBondContact CA-O 3.5Å; V13-S73 VanDerWaalsContact CB-O 3.31Å; V13-S73 WeakPolarHBondContact CB-O 2.96Å; N14-S73 PolarHBondContact N-O 2.93Å; N14-S73 PolarHBondContact O-N 3.22Å; S73-S75 PolarHBondContact O-N 3.14Å
74S97Very high94.2Very high11 Ų1145 Ų458%0.07723%0.23CC..EExtended strand (participates in β ladder)trans-57.5138.2176.7177.10000111.5S10 S76 Y77S10-S74 WeakPolarHBondContact CB-OG 3.09Å; S10-S74 PolarHBondContact OG-OG 3.2Å; S74-S76 WeakPolarHBondContact CB-OG 3.37Å; S74-S76 PolarHBondContact O-N 3.33Å; S74-S76 VanDerWaalsContact O-N 3.13Å; S74-S76 PolarHBondContact OG-N 3.19Å; S74-S76 PolarHBondContact OG-OG 2.74Å; S74-Y77 PolarHBondContact O-N 3.12Å; S74-Y77 VanDerWaalsContact O-N 3.07Å
75S96.7Very high94.7Very high22 Ų2244.8 Ų44.815%0.15423%0.234CC..THydrogen-bonded Turntrans-65.8-10.6174.2-63.10000114.3K12 V13 N14 D44 S73 Y77K12-S75 VanDerWaalsContact C-OG 3.31Å; K12-S75 PolarHBondContact O-N 3.22Å; K12-S75 PolarHBondContact O-OG 3.03Å; V13-S75 VanDerWaalsContact CA-OG 3.27Å; V13-S75 WeakPolarHBondContact CA-OG 3.37Å; V13-S75 PolarHBondContact N-OG 2.84Å; V13-S75 VanDerWaalsContact N-OG 3.14Å; V13-S75 PolarHBondContact O-OG 3.03Å; N14-S75 PolarHBondContact N-OG 2.89Å; N14-S75 WeakPolarHBondContact OD1-CA 3.45Å; N14-S75 WeakPolarHBondContact OD1-CB 3.31Å; N14-S75 PolarHBondContact OD1-OG 3.31Å; D44-S75 VanDerWaalsContact CA-OG 3.31Å; D44-S75 WeakPolarHBondContact CA-OG 3.41Å; D44-S75 PolarHBondContact N-OG 3.22Å; D44-S75 WeakPolarHBondContact OD1-CB 3.3Å; S73-S75 PolarHBondContact O-N 3.14Å; S75-Y77 PolarHBondContact O-N 3.36Å
76S96.1Very high95Very high92 Ų9245.9 Ų45.964%0.64324%0.244SC*.THydrogen-bonded Turntrans-67.5-20.7170.764.10000113.3S74S74-S76 WeakPolarHBondContact CB-OG 3.37Å; S74-S76 PolarHBondContact O-N 3.33Å; S74-S76 VanDerWaalsContact O-N 3.13Å; S74-S76 PolarHBondContact OG-N 3.19Å; S74-S76 PolarHBondContact OG-OG 2.74Å
77Y96.1Very high95.3Very high71 Ų7144.5 Ų44.528%0.27824%0.239SC..SBendtrans-86.3139.8176.3-61.6-54.1000111.2N14 S74 S75 K81 V84N14-Y77 PolarHBondContact ND2-O 3.42Å; S74-Y77 PolarHBondContact O-N 3.12Å; S74-Y77 VanDerWaalsContact O-N 3.07Å; S75-Y77 PolarHBondContact O-N 3.36Å; Y77-K81 HydrophobicContact CD1-CD 4.1Å; Y77-V84 HydrophobicContact CD1-CG1 3.77Å; Y77-V84 HydrophobicContact CD2-CB 3.7Å; Y77-V84 HydrophobicContact CD2-CG1 3.79Å; Y77-V84 HydrophobicContact CD2-CG2 4.23Å; Y77-V84 HydrophobicContact CE1-CB 4.48Å; Y77-V84 HydrophobicContact CE1-CG1 3.97Å; Y77-V84 HydrophobicContact CE2-CB 3.67Å; Y77-V84 HydrophobicContact CE2-CG1 3.99Å; Y77-V84 HydrophobicContact CG-CB 4.14Å; Y77-V84 HydrophobicContact CG-CG1 3.67Å
78P95.3Very high95.3Very high87 Ų8749.7 Ų49.757%0.56526%0.259SS*.PPolyproline II helixtrans-56.4149.5164.6-2231.9000111.5G80 K81P78-G80 PolarHBondContact O-N 2.73Å; P78-K81 VanDerWaalsContact O-CB 3.29Å; P78-K81 WeakPolarHBondContact O-CB 3.25Å; P78-K81 PolarHBondContact O-N 2.95Å
79D93.4Very high95.3Very high51 Ų5152 Ų5227%0.27328%0.275SS..THydrogen-bonded Turntrans-52.9140.5173.6-68.6-35.4000111.3E16 Y37 S40 K43 K81E16-D79 WeakPolarHBondContact OE1-CA 3.46Å; Y37-D79 HydrophobicContact CE1-CB 4.17Å; Y37-D79 HydrophobicContact CE2-CB 4.01Å; S40-D79 VanDerWaalsContact OG-CG 3.28Å; S40-D79 PolarHBondContact OG-OD1 2.51Å; K43-D79 WeakPolarHBondContact CE-OD1 3.19Å; K43-D79 WeakPolarHBondContact CE-OD2 3.42Å; K43-D79 IonicContact NZ-OD1 3.45Å; K43-D79 IonicContact NZ-OD2 2.61Å; K43-D79 PolarHBondContact NZ-OD2 3.47Å; D79-K81 PolarHBondContact O-N 3.36Å; D79-K81 VanDerWaalsContact O-N 3.11Å
80G94.5Very high95Very high14 Ų1460 Ų6014%0.14431%0.312CS..THydrogen-bonded Turntrans70.96.717300000114.2E16 W18 Y37 P78 W82E16-G80 PolarHBondContact OE1-N 3.19Å; W18-G80 VanDerWaalsContact CH2-O 3.3Å; W18-G80 WeakPolarHBondContact CH2-O 3.48Å; Y37-G80 VanDerWaalsContact CG-CA 3.45Å; P78-G80 PolarHBondContact O-N 2.73Å; G80-W82 PolarHBondContact O-N 2.83Å
81K96.2Very high94.9Very high99 Ų9960.5 Ų60.543%0.4331%0.314SS..  trans-65.6124.4179.5-174.6171.8176.1178.90110.7R71 Y77 P78 D79 V84R71-K81 PolarHBondContact NH1-O 3.04Å; R71-K81 PolarHBondContact NH2-O 2.98Å; Y77-K81 HydrophobicContact CD1-CD 4.1Å; P78-K81 VanDerWaalsContact O-CB 3.29Å; P78-K81 WeakPolarHBondContact O-CB 3.25Å; P78-K81 PolarHBondContact O-N 2.95Å; D79-K81 PolarHBondContact O-N 3.36Å; D79-K81 VanDerWaalsContact O-N 3.11Å; K81-V84 HydrophobicContact CB-CG1 4.09Å; K81-V84 HydrophobicContact CD-CG1 3.93Å; K81-V84 HydrophobicContact CG-CG1 3.77Å
82W94.7Very high94.5Very high135 Ų13562.9 Ų62.951%0.51133%0.325SS..SBendtrans-71.5157.5174.9-76.4102000113W18 W35 G80 V84W18-W82 HydrophobicContact CE3-CH2 4.41Å; W18-W82 HydrophobicContact CE3-CZ2 4.38Å; W18-W82 HydrophobicContact CH2-CD2 4.05Å; W18-W82 AromaticContact CH2-CE2 3.89Å; W18-W82 HydrophobicContact CH2-CE3 4.46Å; W18-W82 HydrophobicContact CH2-CG 4.47Å; W18-W82 HydrophobicContact CH2-CZ2 4.23Å; W18-W82 HydrophobicContact CZ3-CD2 4.12Å; W18-W82 AromaticContact CZ3-CE2 3.61Å; W18-W82 HydrophobicContact CZ3-CE3 4.39Å; W18-W82 AromaticContact CZ3-CH2 3.81Å; W18-W82 HydrophobicContact CZ3-CH2 3.81Å; W18-W82 AromaticContact CZ3-CZ2 3.49Å; W18-W82 HydrophobicContact CZ3-CZ2 3.49Å; W18-W82 VanDerWaalsContact CZ3-CZ2 3.49Å; W18-W82 HydrophobicContact CZ3-CZ3 4.24Å; W35-W82 HydrophobicContact CB-CH2 3.57Å; W35-W82 HydrophobicContact CB-CZ2 4.09Å; W35-W82 HydrophobicContact CG-CH2 4.44Å; W35-W82 WeakPolarHBondContact O-CZ2 3.36Å; G80-W82 PolarHBondContact O-N 2.83Å; W82-V84 PolarHBondContact O-N 3.05Å
83N92.8Very high94.2Very high163 Ų16363.3 Ų63.387%0.87233%0.329SS*.SBendtrans56.347171.6-54-37.4000113.7
84V94Very high93.7Very high21 Ų2163.3 Ų63.313%0.12733%0.329CS..  trans-110.1151.7175.2-62.10000110.2Y77 K81 W82 A86Y77-V84 HydrophobicContact CD1-CG1 3.77Å; Y77-V84 HydrophobicContact CD2-CB 3.7Å; Y77-V84 HydrophobicContact CD2-CG1 3.79Å; Y77-V84 HydrophobicContact CD2-CG2 4.23Å; Y77-V84 HydrophobicContact CE1-CB 4.48Å; Y77-V84 HydrophobicContact CE1-CG1 3.97Å; Y77-V84 HydrophobicContact CE2-CB 3.67Å; Y77-V84 HydrophobicContact CE2-CG1 3.99Å; Y77-V84 HydrophobicContact CG-CB 4.14Å; Y77-V84 HydrophobicContact CG-CG1 3.67Å; K81-V84 HydrophobicContact CB-CG1 4.09Å; K81-V84 HydrophobicContact CD-CG1 3.93Å; K81-V84 HydrophobicContact CG-CG1 3.77Å; W82-V84 PolarHBondContact O-N 3.05Å; V84-A86 HydrophobicContact CG2-CB 4.39Å; V84-A86 PolarHBondContact O-N 2.95Å
85Q94.2Very high92.7Very high109 Ų10963.3 Ų63.351%0.50933%0.329SS..  trans-61.1119.3167.9-177.2-178.16.500109L7L7-Q85 PolarHBondContact O-NE2 3.06Å
86A95.2Very high91.7Very high24 Ų2464.7 Ų64.720%0.19833%0.331CS..EExtended strand (participates in β ladder)trans-151.6153.4-176.700000111.2R71 V72 V84R71-A86 HydrophobicContact CG-CB 3.65Å; V72-A86 CarbonylContact O-C 3.59Å; V72-A86 WeakPolarHBondContact O-CA 3.16Å; V72-A86 VanDerWaalsContact O-CB 3.32Å; V72-A86 WeakPolarHBondContact O-CB 3.38Å; V84-A86 HydrophobicContact CG2-CB 4.39Å; V84-A86 PolarHBondContact O-N 2.95Å
87A95.3Very high90.7Very high11 Ų1160.3 Ų60.39%0.09130%0.301CS..EExtended strand (participates in β ladder)trans-92.8135.6161.900000108.8L7 V8 R71 V72L7-A87 HydrophobicContact CB-CB 4.04Å; L7-A87 HydrophobicContact CD1-CB 3.94Å; V8-A87 HydrophobicContact CG2-CB 4.22Å; R71-A87 WeakPolarHBondContact CA-O 3.45Å; V72-A87 HydrophobicContact CB-CB 4.41Å; V72-A87 PolarHBondContact N-O 3.48Å; V72-A87 PolarHBondContact O-N 3.28Å
88W94.6Very high89.3Confident112 Ų11257.5 Ų57.542%0.42429%0.291SS..EExtended strand (participates in β ladder)trans-115.4143.7177.1-68.786.4000109.5W18 W35 A69 R71W18-W88 HydrophobicContact CB-CH2 4.27Å; W18-W88 HydrophobicContact CB-CZ3 3.82Å; W18-W88 AromaticContact CD1-CH2 3.95Å; W18-W88 AromaticContact CD1-CZ3 3.87Å; W18-W88 AromaticContact CD2-CH2 3.76Å; W18-W88 HydrophobicContact CD2-CH2 3.76Å; W18-W88 HydrophobicContact CD2-CZ3 4.21Å; W18-W88 HydrophobicContact CE3-CH2 4.28Å; W18-W88 AromaticContact CG-CH2 3.73Å; W18-W88 HydrophobicContact CG-CH2 3.73Å; W18-W88 AromaticContact CG-CZ3 3.67Å; W18-W88 HydrophobicContact CG-CZ3 3.67Å; W35-W88 HydrophobicContact CZ3-CZ3 4.42Å; A69-W88 HydrophobicContact CB-CE3 4.06Å; A69-W88 HydrophobicContact CB-CZ3 4.43Å; R71-W88 HydrophobicContact CB-CD2 4.05Å; R71-W88 HydrophobicContact CB-CE3 3.83Å; R71-W88 HydrophobicContact CB-CH2 4.14Å; R71-W88 HydrophobicContact CB-CZ2 4.34Å; R71-W88 HydrophobicContact CB-CZ3 3.87Å; R71-W88 VanDerWaalsContact CD-CE2 3.47Å; R71-W88 VanDerWaalsContact CD-CH2 3.49Å; R71-W88 HydrophobicContact CG-CD2 3.91Å; R71-W88 HydrophobicContact CG-CE3 4.18Å; R71-W88 HydrophobicContact CG-CH2 4.17Å; R71-W88 HydrophobicContact CG-CZ2 3.88Å; R71-W88 HydrophobicContact CG-CZ3 4.3Å
89S93.6Very high87.7Confident49 Ų4954.8 Ų54.834%0.34327%0.27SS..PPolyproline II helixtrans-69.9165.9161.469.20000110.2V70V70-S89 PolarHBondContact N-OG 2.89Å; V70-S89 PolarHBondContact O-N 2.83Å
90E90Very high86.5Confident170 Ų17058.3 Ų58.379%0.79429%0.285SS*.PPolyproline II helixtrans-59.9160.4157.7-64.9-180177.900110.1
91D91Very high85.2Confident23 Ų2360.3 Ų60.312%0.12330%0.297CS..PPolyproline II helixtrans-59140.7169.8-71.1-33000109.6L67 Q227 W230L67-D91 HydrophobicContact CD1-CB 4.17Å; D91-Q227 PolarHBondContact OD2-NE2 3.01Å; D91-W230 HydrophobicContact CB-CD2 4.08Å; D91-W230 HydrophobicContact CB-CG 4.06Å; D91-W230 HydrophobicContact CB-CZ2 4.41Å; D91-W230 WeakPolarHBondContact O-CH2 3.36Å; D91-W230 WeakPolarHBondContact O-CZ2 3.44Å
92H90Very high84.1Confident53 Ų5358.1 Ų58.125%0.24529%0.287CS..EExtended strand (participates in β ladder)trans-151.415517568.1100.9000112.2G68 L94 W96G68-H92 PolarHBondContact N-O 2.92Å; G68-H92 PolarHBondContact O-CD2 2.83Å; G68-H92 PolarHBondContact O-N 2.91Å; H92-L94 VanDerWaalsContact CE1-CD2 3.47Å; H92-L94 WeakPolarHBondContact CE1-CD2 3.41Å; H92-L94 PolarHBondContact O-N 3.08Å; H92-W96 AromaticContact CE1-NE1 3.63Å
93A89.8Confident83Confident12 Ų1259.3 Ų59.310%0.09929%0.292CS..EExtended strand (participates in β ladder)trans-60.6128.4170.200000109.8E66 A95 L235 Y238 W243E66-A93 WeakPolarHBondContact O-CA 3.44Å; A93-A95 PolarHBondContact O-N 3.26Å; A93-L235 HydrophobicContact CB-CD2 3.54Å; A93-Y238 HydrophobicContact CB-CD2 3.86Å; A93-Y238 HydrophobicContact CB-CE2 3.95Å; A93-W243 HydrophobicContact CB-CH2 3.76Å; A93-W243 HydrophobicContact CB-CZ2 4.42Å
94L87.6Confident82.5Confident0 Ų058.7 Ų58.70%028%0.284CS..  trans-82.910.4-178.9-68.5-174.9000113.2V17 L38 W65 E66 H92 W96 H97V17-L94 HydrophobicContact CG1-CD1 4.07Å; V17-L94 HydrophobicContact CG1-CD2 4.19Å; L38-L94 HydrophobicContact CD1-CD1 4.12Å; W65-L94 WeakPolarHBondContact O-CD1 3.28Å; E66-L94 PolarHBondContact O-N 2.81Å; H92-L94 VanDerWaalsContact CE1-CD2 3.47Å; H92-L94 WeakPolarHBondContact CE1-CD2 3.41Å; H92-L94 PolarHBondContact O-N 3.08Å; L94-W96 HydrophobicContact CD2-CZ2 4.37Å; L94-W96 PolarHBondContact O-N 2.82Å; L94-H97 VanDerWaalsContact C-CD2 3.43Å; L94-H97 WeakPolarHBondContact CB-NE2 3.34Å; L94-H97 PolarHBondContact O-CD2 2.84Å; L94-H97 PolarHBondContact O-N 2.92Å
95A76.4Confident82.1Confident11 Ų1162.1 Ų62.19%0.09130%0.302CS..G310 helixtrans-36.4-32.4-172.200000117.8A93 H97 L98 W243A93-A95 PolarHBondContact O-N 3.26Å; A95-H97 PolarHBondContact O-N 3.49Å; A95-L98 WeakPolarHBondContact O-CB 3.48Å; A95-L98 PolarHBondContact O-N 3.23Å; A95-L98 VanDerWaalsContact O-N 3.08Å; A95-W243 HydrophobicContact CB-CH2 3.6Å; A95-W243 HydrophobicContact CB-CZ2 4.27Å; A95-W243 HydrophobicContact CB-CZ3 4.09Å
96W74.3Confident81.7Confident52 Ų5259.3 Ų59.320%0.19729%0.294CS..G310 helixtrans-62-22.2175.362.4-89.6000115.2V17 L41 F53 P55 H92 L94V17-W96 HydrophobicContact CG2-CH2 3.96Å; V17-W96 HydrophobicContact CG2-CZ2 4.33Å; L41-W96 HydrophobicContact CD2-CH2 3.73Å; L41-W96 HydrophobicContact CD2-CZ3 4.14Å; F53-W96 HydrophobicContact CD2-CZ3 4.28Å; F53-W96 HydrophobicContact CE2-CD2 4.21Å; F53-W96 AromaticContact CE2-CE3 3.62Å; F53-W96 HydrophobicContact CE2-CE3 3.62Å; F53-W96 AromaticContact CE2-CH2 3.63Å; F53-W96 HydrophobicContact CE2-CH2 3.63Å; F53-W96 HydrophobicContact CE2-CZ2 4.25Å; F53-W96 AromaticContact CE2-CZ3 3.29Å; F53-W96 HydrophobicContact CE2-CZ3 3.29Å; F53-W96 HydrophobicContact CZ-CD2 4.31Å; F53-W96 HydrophobicContact CZ-CE3 4.13Å; F53-W96 AromaticContact CZ-CH2 3.69Å; F53-W96 HydrophobicContact CZ-CH2 3.69Å; F53-W96 AromaticContact CZ-CZ2 3.91Å; F53-W96 HydrophobicContact CZ-CZ2 3.91Å; F53-W96 AromaticContact CZ-CZ3 3.83Å; F53-W96 HydrophobicContact CZ-CZ3 3.83Å; P55-W96 HydrophobicContact CB-CB 3.85Å; P55-W96 HydrophobicContact CB-CD2 4.42Å; P55-W96 HydrophobicContact CB-CE3 3.81Å; P55-W96 HydrophobicContact CB-CG 4.5Å; P55-W96 HydrophobicContact CG-CB 3.92Å; P55-W96 HydrophobicContact CG-CE3 4.24Å; P55-W96 HydrophobicContact CG-CG 4.47Å; H92-W96 AromaticContact CE1-NE1 3.63Å; L94-W96 HydrophobicContact CD2-CZ2 4.37Å; L94-W96 PolarHBondContact O-N 2.82Å
97H75.1Confident81.5Confident0 Ų060.2 Ų60.20%030%0.301CS..G310 helixtrans-89.8-6.2173.378.8154.6000113.8A58 F62 W65 L94 A95 E99A58-H97 HydrophobicContact CB-CB 4.16Å; A58-H97 PolarHBondContact N-O 2.67Å; F62-H97 PolarHBondContact O-CE1 3.17Å; W65-H97 PolarHBondContact O-CE1 3.11Å; W65-H97 PolarHBondContact O-NE2 2.82Å; L94-H97 VanDerWaalsContact C-CD2 3.43Å; L94-H97 WeakPolarHBondContact CB-NE2 3.34Å; L94-H97 PolarHBondContact O-CD2 2.84Å; L94-H97 PolarHBondContact O-N 2.92Å; A95-H97 PolarHBondContact O-N 3.49Å; H97-E99 PolarHBondContact O-N 3.08Å
98L67.1Low81.3Confident12 Ų1260.6 Ų60.66%0.06331%0.306CS..SBendtrans-90.222.2177.3-49.5-179.8000112S63 E66 A95 E100 S101 F102 W109S63-L98 WeakPolarHBondContact O-CD2 3.41Å; E66-L98 HydrophobicContact CG-CD1 4.13Å; A95-L98 WeakPolarHBondContact O-CB 3.48Å; A95-L98 PolarHBondContact O-N 3.23Å; A95-L98 VanDerWaalsContact O-N 3.08Å; L98-E100 PolarHBondContact O-N 3.12Å; L98-E100 VanDerWaalsContact O-N 3.17Å; L98-S101 PolarHBondContact O-OG 2.8Å; L98-F102 PolarHBondContact O-N 2.89Å; L98-W109 HydrophobicContact CD1-CH2 3.52Å; L98-W109 HydrophobicContact CD1-CZ2 3.31Å
99E62.9Low81Confident30 Ų3056.9 Ų56.914%0.1429%0.292CS..Hα-helixtrans-55.7-40.3-148.1178.9-165.4165.600115.4K56 I57 H97 R103K56-E99 WeakPolarHBondContact CA-OE2 3.45Å; I57-E99 HydrophobicContact CG1-CB 3.68Å; I57-E99 HydrophobicContact CG1-CG 4.24Å; I57-E99 PolarHBondContact N-OE2 2.79Å; H97-E99 PolarHBondContact O-N 3.08Å; E99-R103 HydrophobicContact CG-CG 4.03Å; E99-R103 WeakPolarHBondContact O-CB 3.36Å; E99-R103 WeakPolarHBondContact O-CG 3.38Å; E99-R103 PolarHBondContact O-N 3.35Å; E99-R103 IonicContact OE1-CZ 3.42Å; E99-R103 IonicContact OE1-NE 2.66Å; E99-R103 PolarHBondContact OE1-NE 3.35Å; E99-R103 IonicContact OE1-NH1 3.53Å; E99-R103 PolarHBondContact OE1-NH1 2.86Å; E99-R103 IonicContact OE1-NH2 2.78Å; E99-R103 PolarHBondContact OE1-NH2 3.32Å; E99-R103 IonicContact OE2-NH2 3.56Å
100E67.6Low80.9Confident124 Ų12454.5 Ų54.558%0.57928%0.276SS*.Hα-helixtrans-71.8-49.2-170.7-168.8163-154.500113I57 L98 R103 Q104I57-E100 HydrophobicContact CD1-CB 3.93Å; L98-E100 PolarHBondContact O-N 3.12Å; L98-E100 VanDerWaalsContact O-N 3.17Å; E100-R103 PolarHBondContact O-N 3.42Å; E100-Q104 VanDerWaalsContact O-CG 3.26Å; E100-Q104 WeakPolarHBondContact O-CG 3.47Å; E100-Q104 PolarHBondContact O-N 3.08Å; E100-Q104 VanDerWaalsContact O-N 3.13Å
101S67.3Low81.1Confident57 Ų5748.8 Ų48.840%0.39925%0.25SS..Hα-helixtrans-65.9-42.117762.80000112.1L98 Q104 N105L98-S101 PolarHBondContact O-OG 2.8Å; S101-Q104 PolarHBondContact O-N 3.25Å; S101-N105 PolarHBondContact O-N 3.17Å
102F72.6Confident81.2Confident52 Ų5252.9 Ų52.923%0.22827%0.272CS..Hα-helixtrans-68.3-37.1178.3-169.8-95.7000112.5L98 S106 W109 W243L98-F102 PolarHBondContact O-N 2.89Å; F102-S106 WeakPolarHBondContact O-CA 3.33Å; F102-S106 VanDerWaalsContact O-CB 3.24Å; F102-S106 WeakPolarHBondContact O-CB 3.5Å; F102-S106 PolarHBondContact O-N 3.05Å; F102-W109 HydrophobicContact CD2-CD2 4.26Å; F102-W109 AromaticContact CD2-CE3 3.65Å; F102-W109 HydrophobicContact CD2-CE3 3.65Å; F102-W109 HydrophobicContact CD2-CZ3 4.05Å; F102-W109 HydrophobicContact CE2-CE3 4.13Å; F102-W109 HydrophobicContact CE2-CZ3 4.3Å; F102-W243 HydrophobicContact CE2-CD2 4.34Å; F102-W243 HydrophobicContact CE2-CE3 4.19Å
103R72.6Confident81.3Confident160 Ų16053.3 Ų53.360%0.60427%0.273SS*.Hα-helixtrans-72.3-31.7177.1-77.8-172.8-179.9173.315.3113.5E99 E100E99-R103 HydrophobicContact CG-CG 4.03Å; E99-R103 WeakPolarHBondContact O-CB 3.36Å; E99-R103 WeakPolarHBondContact O-CG 3.38Å; E99-R103 PolarHBondContact O-N 3.35Å; E99-R103 IonicContact OE1-CZ 3.42Å; E99-R103 IonicContact OE1-NE 2.66Å; E99-R103 PolarHBondContact OE1-NE 3.35Å; E99-R103 IonicContact OE1-NH1 3.53Å; E99-R103 PolarHBondContact OE1-NH1 2.86Å; E99-R103 IonicContact OE1-NH2 2.78Å; E99-R103 PolarHBondContact OE1-NH2 3.32Å; E99-R103 IonicContact OE2-NH2 3.56Å; E100-R103 PolarHBondContact O-N 3.42Å
104Q80.9Confident81.7Confident150 Ų15052.8 Ų52.870%0.70127%0.269SS*.Hα-helixtrans-72-46.2178.5-73.7175.914.300111.6E100 S101E100-Q104 VanDerWaalsContact O-CG 3.26Å; E100-Q104 WeakPolarHBondContact O-CG 3.47Å; E100-Q104 PolarHBondContact O-N 3.08Å; E100-Q104 VanDerWaalsContact O-N 3.13Å; S101-Q104 PolarHBondContact O-N 3.25Å
105N86.8Confident82.1Confident94 Ų9455.9 Ų55.950%0.50329%0.285SS..Hα-helixtrans-15782.3178.1-176.57.2000111.1S101 A107 G108 W109S101-N105 PolarHBondContact O-N 3.17Å; N105-A107 VanDerWaalsContact C-N 3.3Å; N105-A107 PolarHBondContact O-N 3.22Å; N105-G108 PolarHBondContact O-N 2.88Å; N105-G108 PolarHBondContact OD1-N 2.71Å; N105-W109 WeakPolarHBondContact O-CB 3.33Å; N105-W109 PolarHBondContact O-N 3.4Å
106S85.4Confident83Confident50 Ų5058.3 Ų58.335%0.3531%0.305SS..Hα-helixtrans-58.2-40.7-178.851.90000113F102 A110F102-S106 WeakPolarHBondContact O-CA 3.33Å; F102-S106 VanDerWaalsContact O-CB 3.24Å; F102-S106 WeakPolarHBondContact O-CB 3.5Å; F102-S106 PolarHBondContact O-N 3.05Å; S106-A110 WeakPolarHBondContact O-CB 3.46Å; S106-A110 PolarHBondContact O-N 2.97Å
107A90.4Very high84.1Confident43 Ų4356.8 Ų56.836%0.35530%0.299SS..Hα-helixtrans-68.4-42.6-179.800000112.2N105 A110 L111 W243N105-A107 VanDerWaalsContact C-N 3.3Å; N105-A107 PolarHBondContact O-N 3.22Å; A107-A110 PolarHBondContact O-N 3.06Å; A107-L111 WeakPolarHBondContact O-CB 3.42Å; A107-L111 PolarHBondContact O-N 3.02Å; A107-W243 WeakPolarHBondContact CA-O 3.3Å
108G91.3Very high85.1Confident19 Ų1957.8 Ų57.820%0.19630%0.304CS..Hα-helixtrans-64.7-45.6175.200000112.3N105 A110 L111 D112N105-G108 PolarHBondContact O-N 2.88Å; N105-G108 PolarHBondContact OD1-N 2.71Å; G108-A110 VanDerWaalsContact C-N 3.34Å; G108-A110 PolarHBondContact O-N 2.91Å; G108-L111 WeakPolarHBondContact O-CB 3.34Å; G108-L111 PolarHBondContact O-N 3.06Å; G108-D112 PolarHBondContact O-N 3.04Å
109W88.5Confident86.5Confident33 Ų3363.5 Ų63.513%0.12533%0.329CS..Hα-helixtrans-59.1-45.5174.9175.789.3000111.9L98 F102 N105 L111 D112 K113 Y239 W243L98-W109 HydrophobicContact CD1-CH2 3.52Å; L98-W109 HydrophobicContact CD1-CZ2 3.31Å; F102-W109 HydrophobicContact CD2-CD2 4.26Å; F102-W109 AromaticContact CD2-CE3 3.65Å; F102-W109 HydrophobicContact CD2-CE3 3.65Å; F102-W109 HydrophobicContact CD2-CZ3 4.05Å; F102-W109 HydrophobicContact CE2-CE3 4.13Å; F102-W109 HydrophobicContact CE2-CZ3 4.3Å; N105-W109 WeakPolarHBondContact O-CB 3.33Å; N105-W109 PolarHBondContact O-N 3.4Å; W109-L111 VanDerWaalsContact C-N 3.32Å; W109-L111 PolarHBondContact O-N 3.04Å; W109-D112 PolarHBondContact O-N 2.88Å; W109-K113 HydrophobicContact CD2-CG 4.25Å; W109-K113 HydrophobicContact CE3-CG 4.42Å; W109-K113 HydrophobicContact CH2-CG 3.96Å; W109-K113 HydrophobicContact CZ2-CD 4.26Å; W109-K113 HydrophobicContact CZ2-CG 3.72Å; W109-K113 HydrophobicContact CZ3-CG 4.3Å; W109-K113 WeakPolarHBondContact O-CG 3.28Å; W109-K113 PolarHBondContact O-N 3.33Å; W109-K113 VanDerWaalsContact O-N 3.08Å; W109-Y239 HydrophobicContact CH2-CD1 4.14Å; W109-Y239 AromaticContact CH2-CE1 3.53Å; W109-Y239 HydrophobicContact CH2-CE1 3.53Å; W109-Y239 AromaticContact CZ3-CD1 3.92Å; W109-Y239 HydrophobicContact CZ3-CD1 3.92Å; W109-Y239 AromaticContact CZ3-CE1 3.75Å; W109-Y239 HydrophobicContact CZ3-CE1 3.75Å; W109-W243 HydrophobicContact CH2-CZ3 4.46Å; W109-W243 AromaticContact CZ3-CE3 3.95Å; W109-W243 HydrophobicContact CZ3-CE3 3.95Å; W109-W243 AromaticContact CZ3-CZ3 3.91Å; W109-W243 HydrophobicContact CZ3-CZ3 3.91Å
110A91.8Very high88Confident0 Ų065 Ų650%034%0.338CS..Hα-helixtrans-65.6-36178.300000112S106 A107 G108 K113 C114 W243S106-A110 WeakPolarHBondContact O-CB 3.46Å; S106-A110 PolarHBondContact O-N 2.97Å; A107-A110 PolarHBondContact O-N 3.06Å; G108-A110 VanDerWaalsContact C-N 3.34Å; G108-A110 PolarHBondContact O-N 2.91Å; A110-K113 PolarHBondContact O-N 2.89Å; A110-C114 WeakPolarHBondContact O-CB 3.45Å; A110-C114 PolarHBondContact O-N 3.49Å; A110-W243 HydrophobicContact CB-CB 3.52Å
111L94.6Very high89.3Confident50 Ų5059.5 Ų59.526%0.26231%0.312SS..Hα-helixtrans-64.1-45.4173.8179.159.4000111.1A107 G108 W109 K113 C114 L115 N246 Y249A107-L111 WeakPolarHBondContact O-CB 3.42Å; A107-L111 PolarHBondContact O-N 3.02Å; G108-L111 WeakPolarHBondContact O-CB 3.34Å; G108-L111 PolarHBondContact O-N 3.06Å; W109-L111 VanDerWaalsContact C-N 3.32Å; W109-L111 PolarHBondContact O-N 3.04Å; L111-K113 VanDerWaalsContact C-N 3.26Å; L111-K113 PolarHBondContact O-N 3.44Å; L111-C114 WeakPolarHBondContact O-CB 3.23Å; L111-C114 PolarHBondContact O-N 3.32Å; L111-C114 VanDerWaalsContact O-N 3.13Å; L111-L115 HydrophobicContact CD1-CD1 4.22Å; L111-L115 HydrophobicContact CD1-CD2 4.49Å; L111-L115 HydrophobicContact CD1-CG 4.06Å; L111-L115 HydrophobicContact CG-CD1 4.08Å; L111-L115 HydrophobicContact CG-CG 4.35Å; L111-L115 VanDerWaalsContact O-CG 3.31Å; L111-L115 WeakPolarHBondContact O-CG 3.23Å; L111-L115 PolarHBondContact O-N 2.83Å; L111-N246 HydrophobicContact CD1-CB 4.19Å; L111-Y249 HydrophobicContact CD1-CE2 4.42Å
112D93.1Very high90.7Very high108 Ų10861.2 Ų61.258%0.57832%0.316SS*.Hα-helixtrans-59.1-40.2177.2-70.2-23.2000111.4G108 W109 L115 A116G108-D112 PolarHBondContact O-N 3.04Å; W109-D112 PolarHBondContact O-N 2.88Å; D112-L115 PolarHBondContact O-N 3.06Å; D112-A116 WeakPolarHBondContact O-CB 3.4Å; D112-A116 PolarHBondContact O-N 2.86Å
113K92.3Very high91.7Very high63 Ų6365.2 Ų65.227%0.27434%0.336SS..Hα-helixtrans-65.2-44.5173.3-69.4-60.4-170.9166.50113E66 W109 A110 L111 L115 A116 W117 Y239E66-K113 WeakPolarHBondContact OE1-CE 3.26Å; E66-K113 IonicContact OE1-NZ 3.65Å; E66-K113 PolarHBondContact OE1-NZ 3.16Å; E66-K113 IonicContact OE2-NZ 2.75Å; E66-K113 PolarHBondContact OE2-NZ 2.92Å; W109-K113 HydrophobicContact CD2-CG 4.25Å; W109-K113 HydrophobicContact CE3-CG 4.42Å; W109-K113 HydrophobicContact CH2-CG 3.96Å; W109-K113 HydrophobicContact CZ2-CD 4.26Å; W109-K113 HydrophobicContact CZ2-CG 3.72Å; W109-K113 HydrophobicContact CZ3-CG 4.3Å; W109-K113 WeakPolarHBondContact O-CG 3.28Å; W109-K113 PolarHBondContact O-N 3.33Å; W109-K113 VanDerWaalsContact O-N 3.08Å; A110-K113 PolarHBondContact O-N 2.89Å; L111-K113 VanDerWaalsContact C-N 3.26Å; L111-K113 PolarHBondContact O-N 3.44Å; K113-L115 VanDerWaalsContact C-N 3.33Å; K113-L115 PolarHBondContact O-N 3.11Å; K113-A116 PolarHBondContact O-N 2.65Å; K113-W117 WeakPolarHBondContact O-CB 3.47Å; K113-W117 PolarHBondContact O-N 2.93Å; K113-Y239 HydrophobicContact CB-CD1 4Å; K113-Y239 HydrophobicContact CB-CD2 3.7Å; K113-Y239 HydrophobicContact CB-CE1 4.39Å; K113-Y239 HydrophobicContact CB-CE2 4.11Å; K113-Y239 HydrophobicContact CB-CG 3.65Å; K113-Y239 HydrophobicContact CG-CD1 4.48Å; K113-Y239 HydrophobicContact CG-CE1 4.49Å
114C96.3Very high92.7Very high0 Ų058.5 Ų58.50%031%0.312CS..Hα-helixtrans-59.8-43175.9-179.70000111.8A110 L111 W117 D118 C240 Y249A110-C114 WeakPolarHBondContact O-CB 3.45Å; A110-C114 PolarHBondContact O-N 3.49Å; L111-C114 WeakPolarHBondContact O-CB 3.23Å; L111-C114 PolarHBondContact O-N 3.32Å; L111-C114 VanDerWaalsContact O-N 3.13Å; C114-W117 PolarHBondContact O-N 2.83Å; C114-D118 PolarHBondContact O-N 3.41Å; C114-C240 VanDerWaalsContact CA-SG 3.55Å; C114-C240 HydrophobicContact CB-CB 4Å; C114-C240 WeakPolarHBondContact CB-SG 3.01Å; C114-C240 WeakPolarHBondContact SG-CA 3.43Å; C114-C240 WeakPolarHBondContact SG-CB 3.18Å; C114-C240 CovalentContact SG-SG 2.04Å; C114-C240 PolarHBondContact SG-SG 3.28Å; C114-Y249 VanDerWaalsContact SG-CB 3.56Å
115L97.4Very high93.4Very high66 Ų6653.7 Ų53.735%0.34629%0.294SS..Hα-helixtrans-68.7-38.5178.2-67.9175.4000112.5L111 D112 K113 W117 D118 K119 Y249L111-L115 HydrophobicContact CD1-CD1 4.22Å; L111-L115 HydrophobicContact CD1-CD2 4.49Å; L111-L115 HydrophobicContact CD1-CG 4.06Å; L111-L115 HydrophobicContact CG-CD1 4.08Å; L111-L115 HydrophobicContact CG-CG 4.35Å; L111-L115 VanDerWaalsContact O-CG 3.31Å; L111-L115 WeakPolarHBondContact O-CG 3.23Å; L111-L115 PolarHBondContact O-N 2.83Å; D112-L115 PolarHBondContact O-N 3.06Å; K113-L115 VanDerWaalsContact C-N 3.33Å; K113-L115 PolarHBondContact O-N 3.11Å; L115-W117 VanDerWaalsContact C-N 3.34Å; L115-D118 PolarHBondContact O-N 3.21Å; L115-K119 PolarHBondContact O-N 3.08Å; L115-Y249 HydrophobicContact CD2-CD1 4.39Å; L115-Y249 HydrophobicContact CD2-CD2 4.5Å; L115-Y249 HydrophobicContact CD2-CE1 3.77Å; L115-Y249 HydrophobicContact CD2-CE2 3.91Å
116A95.2Very high93.7Very high61 Ų6153.7 Ų53.750%0.50429%0.294SS..Hα-helixtrans-62.8-42.4173.400000111.5D112 K113 K119 L120D112-A116 WeakPolarHBondContact O-CB 3.4Å; D112-A116 PolarHBondContact O-N 2.86Å; K113-A116 PolarHBondContact O-N 2.65Å; A116-K119 PolarHBondContact O-N 2.96Å; A116-L120 PolarHBondContact O-N 2.85Å; A116-L120 VanDerWaalsContact O-N 3.07Å
117W95.9Very high94.2Very high20 Ų2051.5 Ų51.58%0.07628%0.278CS..Hα-helixtrans-65-44.6174.1171.384.3000112.5K113 C114 L115 K119 L120 E121 Y232 Y249 Y250 H253K113-W117 WeakPolarHBondContact O-CB 3.47Å; K113-W117 PolarHBondContact O-N 2.93Å; C114-W117 PolarHBondContact O-N 2.83Å; L115-W117 VanDerWaalsContact C-N 3.34Å; W117-K119 VanDerWaalsContact C-N 3.26Å; W117-K119 PolarHBondContact O-N 2.98Å; W117-L120 PolarHBondContact O-N 2.87Å; W117-L120 VanDerWaalsContact O-N 3.13Å; W117-E121 HydrophobicContact CD2-CG 4.01Å; W117-E121 VanDerWaalsContact CE2-CG 3.47Å; W117-E121 HydrophobicContact CG-CG 4.46Å; W117-E121 HydrophobicContact CH2-CG 4.25Å; W117-E121 HydrophobicContact CZ2-CG 3.64Å; W117-E121 WeakPolarHBondContact O-CG 3.42Å; W117-E121 PolarHBondContact O-N 3.32Å; W117-Y232 PolarHBondContact NE1-O 2.88Å; W117-Y249 WeakPolarHBondContact CZ3-O 3.34Å; W117-Y250 AromaticContact CH2-CD2 3.8Å; W117-Y250 HydrophobicContact CH2-CD2 3.8Å; W117-Y250 HydrophobicContact CH2-CG 4.34Å; W117-Y250 HydrophobicContact CZ2-CD2 4.14Å; W117-Y250 HydrophobicContact CZ2-CE2 4.48Å; W117-Y250 HydrophobicContact CZ3-CD2 4.39Å; W117-H253 HydrophobicContact CH2-CB 3.87Å; W117-H253 AromaticContact CH2-CD2 3.76Å; W117-H253 HydrophobicContact CZ2-CB 4.33Å; W117-H253 AromaticContact CZ3-CD2 3.77Å
118D97.7Very high94.4Very high21 Ų2152.2 Ų52.211%0.11228%0.275CS..Hα-helixtrans-57.2-42.1175.5173.562.3000111C114 L115 E121 N122 Y249 K252 H253C114-D118 PolarHBondContact O-N 3.41Å; L115-D118 PolarHBondContact O-N 3.21Å; D118-E121 PolarHBondContact O-N 2.88Å; D118-N122 VanDerWaalsContact O-CG 3.24Å; D118-N122 PolarHBondContact O-N 2.86Å; D118-N122 VanDerWaalsContact O-N 3.15Å; D118-N122 PolarHBondContact O-ND2 3.36Å; D118-Y249 HydrophobicContact CB-CD1 4.13Å; D118-K252 IonicContact OD1-NZ 2.65Å; D118-K252 PolarHBondContact OD1-NZ 3Å; D118-K252 IonicContact OD2-NZ 3.8Å; D118-H253 PolarHBondContact O-NE2 2.92Å; D118-H253 IonicContact OD1-CD2 2.65Å; D118-H253 PolarHBondContact OD1-CD2 3.29Å; D118-H253 IonicContact OD1-CE1 2.98Å; D118-H253 IonicContact OD1-NE2 2.87Å; D118-H253 PolarHBondContact OD1-NE2 2.93Å
119K96.9Very high94.4Very high132 Ų13256.2 Ų56.257%0.57430%0.296SS*.Hα-helixtrans-61-48.8175.5-173.1-175.1172.9-167.40111.7L115 A116 W117 E121 N122 E123L115-K119 PolarHBondContact O-N 3.08Å; A116-K119 PolarHBondContact O-N 2.96Å; W117-K119 VanDerWaalsContact C-N 3.26Å; W117-K119 PolarHBondContact O-N 2.98Å; K119-E121 PolarHBondContact O-N 3.21Å; K119-N122 WeakPolarHBondContact O-CB 3.32Å; K119-N122 PolarHBondContact O-N 2.83Å; K119-E123 WeakPolarHBondContact CE-OE1 3.4Å; K119-E123 PolarHBondContact O-N 2.55Å
120L93.6Very high94.5Very high62 Ų6257.9 Ų57.933%0.32531%0.306SS..Hα-helixtrans-58.8-46.8177.7174.663.5000111.4A116 W117 N122 E123 L124A116-L120 PolarHBondContact O-N 2.85Å; A116-L120 VanDerWaalsContact O-N 3.07Å; W117-L120 PolarHBondContact O-N 2.87Å; W117-L120 VanDerWaalsContact O-N 3.13Å; L120-N122 PolarHBondContact O-N 2.86Å; L120-E123 WeakPolarHBondContact O-CA 3.2Å; L120-E123 WeakPolarHBondContact O-CB 3.25Å; L120-E123 PolarHBondContact O-N 3.43Å; L120-L124 HydrophobicContact CD1-CD1 4.44Å; L120-L124 HydrophobicContact CD1-CD2 4.37Å; L120-L124 HydrophobicContact CD1-CG 4.2Å; L120-L124 HydrophobicContact CG-CD1 4.04Å; L120-L124 HydrophobicContact CG-CG 4.24Å; L120-L124 WeakPolarHBondContact O-CG 3.32Å; L120-L124 PolarHBondContact O-N 3.19Å
121E95.8Very high94.6Very high8 Ų859.2 Ų59.24%0.03731%0.312CS..Hα-helixtrans-60.1-33.4179.3-75.5-78.7147.700112.8W117 D118 K119 E123 L124 R209 H253 R254W117-E121 HydrophobicContact CD2-CG 4.01Å; W117-E121 VanDerWaalsContact CE2-CG 3.47Å; W117-E121 HydrophobicContact CG-CG 4.46Å; W117-E121 HydrophobicContact CH2-CG 4.25Å; W117-E121 HydrophobicContact CZ2-CG 3.64Å; W117-E121 WeakPolarHBondContact O-CG 3.42Å; W117-E121 PolarHBondContact O-N 3.32Å; D118-E121 PolarHBondContact O-N 2.88Å; K119-E121 PolarHBondContact O-N 3.21Å; E121-E123 PolarHBondContact O-N 3.39Å; E121-L124 PolarHBondContact O-N 3.43Å; E121-R209 VanDerWaalsContact CD-NH2 3.33Å; E121-R209 IonicContact OE1-CZ 3.62Å; E121-R209 IonicContact OE1-NE 3.14Å; E121-R209 PolarHBondContact OE1-NE 3.4Å; E121-R209 IonicContact OE1-NH2 3.39Å; E121-R209 IonicContact OE2-CZ 2.64Å; E121-R209 IonicContact OE2-NE 2.76Å; E121-R209 PolarHBondContact OE2-NE 3.19Å; E121-R209 IonicContact OE2-NH2 2.76Å; E121-R209 PolarHBondContact OE2-NH2 2.96Å; E121-H253 HydrophobicContact CB-CB 4.39Å; E121-H253 VanDerWaalsContact CB-CE1 3.48Å; E121-H253 WeakPolarHBondContact CB-CE1 3.42Å; E121-H253 WeakPolarHBondContact CB-NE2 3.39Å; E121-H253 HydrophobicContact CG-CB 4.37Å; E121-R254 IonicContact OE1-CZ 3.94Å; E121-R254 IonicContact OE1-NH1 3.12Å; E121-R254 IonicContact OE1-NH2 3.8Å; E121-R254 PolarHBondContact OE1-NH2 2.64Å; E121-R254 IonicContact OE2-CZ 3.26Å; E121-R254 IonicContact OE2-NH1 3.86Å; E121-R254 PolarHBondContact OE2-NH1 3.4Å; E121-R254 IonicContact OE2-NH2 3.18Å
122N95.4Very high94.6Very high93 Ų9359.2 Ų59.250%0.49731%0.312SS..Hα-helixtrans-67.4-22.8173.2-62.6-54.5000113D118 K119 L120 K252 H253D118-N122 VanDerWaalsContact O-CG 3.24Å; D118-N122 PolarHBondContact O-N 2.86Å; D118-N122 VanDerWaalsContact O-N 3.15Å; D118-N122 PolarHBondContact O-ND2 3.36Å; K119-N122 WeakPolarHBondContact O-CB 3.32Å; K119-N122 PolarHBondContact O-N 2.83Å; L120-N122 PolarHBondContact O-N 2.86Å; N122-K252 PolarHBondContact OD1-NZ 3.36Å; N122-H253 PolarHBondContact OD1-CE1 2.86Å
123E94.4Very high94.7Very high136 Ų13656.3 Ų56.364%0.63630%0.297SS*.Hα-helixtrans-90-22.1177.8-64.2173.2-172.400112K119 L120 E121K119-E123 WeakPolarHBondContact CE-OE1 3.4Å; K119-E123 PolarHBondContact O-N 2.55Å; L120-E123 WeakPolarHBondContact O-CA 3.2Å; L120-E123 WeakPolarHBondContact O-CB 3.25Å; L120-E123 PolarHBondContact O-N 3.43Å; E121-E123 PolarHBondContact O-N 3.39Å
124L93.9Very high94.9Very high20 Ų2053.3 Ų53.311%0.10528%0.284CS..SBendtrans-78.9154.4-178.8-69.5178.3000113P26 L120 E121P26-L124 HydrophobicContact CB-CD2 3.29Å; P26-L124 HydrophobicContact CG-CD2 3.61Å; L120-L124 HydrophobicContact CD1-CD1 4.44Å; L120-L124 HydrophobicContact CD1-CD2 4.37Å; L120-L124 HydrophobicContact CD1-CG 4.2Å; L120-L124 HydrophobicContact CG-CD1 4.04Å; L120-L124 HydrophobicContact CG-CG 4.24Å; L120-L124 WeakPolarHBondContact O-CG 3.32Å; L120-L124 PolarHBondContact O-N 3.19Å; E121-L124 PolarHBondContact O-N 3.43Å
125P93.9Very high94.9Very high49 Ų4953.3 Ų53.332%0.31828%0.284SS..  trans-57.8142.8172.1-24.534.3000112.8Y27 F127 Y181 R209Y27-P125 HydrophobicContact CD2-CG 3.85Å; Y27-P125 HydrophobicContact CE2-CG 4.06Å; P125-F127 PolarHBondContact O-N 3.02Å; P125-F127 VanDerWaalsContact O-N 3.16Å; P125-Y181 HydrophobicContact CB-CD1 4.24Å; P125-Y181 HydrophobicContact CB-CE1 3.44Å; P125-Y181 VanDerWaalsContact CB-CE1 3.44Å; P125-Y181 HydrophobicContact CG-CE1 4.26Å; P125-R209 PolarHBondContact O-NH1 3.48Å
126N94.4Very high94.9Very high94 Ų9450.5 Ų50.550%0.50327%0.269SS..  trans-72.7104.1173.8-177.76.1000110.6L128N126-L128 VanDerWaalsContact OD1-CB 3.26Å; N126-L128 WeakPolarHBondContact OD1-CB 3.43Å; N126-L128 WeakPolarHBondContact OD1-CG 3.38Å; N126-L128 PolarHBondContact OD1-N 3.5Å
127F95.2Very high95Very high3 Ų348.8 Ų48.81%0.01325%0.253CS..G310 helixtrans-83-14.7179.970.6-91000113.7P125 T129 E130 I131 Y181 A183 P207 D208 R209P125-F127 PolarHBondContact O-N 3.02Å; P125-F127 VanDerWaalsContact O-N 3.16Å; F127-T129 PolarHBondContact O-N 2.94Å; F127-E130 PolarHBondContact O-N 2.96Å; F127-I131 HydrophobicContact CD2-CD1 4.05Å; F127-I131 HydrophobicContact CD2-CG1 4.04Å; F127-I131 HydrophobicContact CE2-CD1 4.25Å; F127-I131 HydrophobicContact CE2-CG1 4.3Å; F127-Y181 HydrophobicContact CB-CD1 4.38Å; F127-Y181 HydrophobicContact CB-CD2 3.92Å; F127-Y181 HydrophobicContact CB-CG 3.72Å; F127-A183 HydrophobicContact CB-CB 4.06Å; F127-A183 HydrophobicContact CD2-CB 3.32Å; F127-A183 HydrophobicContact CE2-CB 4Å; F127-A183 HydrophobicContact CG-CB 4Å; F127-P207 HydrophobicContact CE2-CB 3.97Å; F127-P207 HydrophobicContact CZ-CB 4.49Å; F127-D208 WeakPolarHBondContact CE2-O 3.12Å; F127-R209 HydrophobicContact CD1-CB 4.16Å; F127-R209 HydrophobicContact CD1-CG 4.32Å; F127-R209 HydrophobicContact CE1-CB 3.77Å; F127-R209 HydrophobicContact CE1-CG 4.39Å; F127-R209 HydrophobicContact CZ-CB 4.01Å
128L94.3Very high95.1Very high58 Ų5849 Ų4930%0.30426%0.255SS..G310 helixtrans-62.8-15-176.1-57.6175000113N126 E130 P207 P255N126-L128 VanDerWaalsContact OD1-CB 3.26Å; N126-L128 WeakPolarHBondContact OD1-CB 3.43Å; N126-L128 WeakPolarHBondContact OD1-CG 3.38Å; N126-L128 PolarHBondContact OD1-N 3.5Å; L128-E130 VanDerWaalsContact C-N 3.26Å; L128-E130 PolarHBondContact O-N 3.31Å; L128-P207 HydrophobicContact CD2-CB 3.76Å; L128-P207 HydrophobicContact CD2-CG 3.45Å; L128-P207 VanDerWaalsContact CD2-CG 3.45Å; L128-P255 HydrophobicContact CD1-CG 3.75Å
129T91.3Very high95.1Very high104 Ų10449.7 Ų49.764%0.63826%0.264SS*.G310 helixtrans-70.7-17.4-179.759.30000114.3F127F127-T129 PolarHBondContact O-N 2.94Å
130E91.3Very high95.2Very high68 Ų6843.6 Ų43.632%0.31824%0.237SC..G310 helixtrans-113.4-0.2-178.2-65.3-173.5141.700113.6F127 L128 T178 K180 Y181F127-E130 PolarHBondContact O-N 2.96Å; L128-E130 VanDerWaalsContact C-N 3.26Å; L128-E130 PolarHBondContact O-N 3.31Å; E130-T178 HydrophobicContact CB-CG2 3.66Å; E130-T178 WeakPolarHBondContact O-CG2 3.49Å; E130-T178 WeakPolarHBondContact OE2-CB 3.36Å; E130-T178 PolarHBondContact OE2-OG1 2.84Å; E130-K180 WeakPolarHBondContact OE1-CB 3.19Å; E130-K180 WeakPolarHBondContact OE2-CB 3.49Å; E130-K180 PolarHBondContact OE2-N 2.76Å; E130-Y181 HydrophobicContact CG-CD2 4.3Å; E130-Y181 HydrophobicContact CG-CE2 4.48Å; E130-Y181 VanDerWaalsContact OE2-CD2 3.25Å; E130-Y181 WeakPolarHBondContact OE2-CD2 3.48Å; E130-Y181 PolarHBondContact OE2-N 2.86Å
131I93.6Very high95.4Very high27 Ų2740.7 Ų40.714%0.13822%0.223CC..PPolyproline II helixtrans-70.7135-176.2-71.4-58000110.8F127 T178 A183 G184 Q185 P207F127-I131 HydrophobicContact CD2-CD1 4.05Å; F127-I131 HydrophobicContact CD2-CG1 4.04Å; F127-I131 HydrophobicContact CE2-CD1 4.25Å; F127-I131 HydrophobicContact CE2-CG1 4.3Å; I131-T178 HydrophobicContact CD1-CG2 3.95Å; I131-A183 HydrophobicContact CD1-CB 3.6Å; I131-G184 WeakPolarHBondContact CD1-O 3.45Å; I131-Q185 HydrophobicContact CG2-CB 4.05Å; I131-Q185 HydrophobicContact CG2-CG 4.16Å; I131-P207 HydrophobicContact CD1-CB 4.4Å; I131-P207 HydrophobicContact CG1-CB 4.2Å; I131-P207 HydrophobicContact CG2-CB 4.33Å
132I93.9Very high95.5Very high51 Ų5146.2 Ų46.226%0.26224%0.243SC..PPolyproline II helixtrans-68.8143.2173.5-170172.3000111R147 F148 A174 Q185I132-R147 HydrophobicContact CD1-CB 3.98Å; I132-R147 HydrophobicContact CD1-CG 4.29Å; I132-F148 HydrophobicContact CD1-CE2 4.06Å; I132-F148 HydrophobicContact CD1-CZ 3.78Å; I132-F148 HydrophobicContact CG1-CZ 4.09Å; I132-F148 HydrophobicContact CG2-CE1 4.1Å; I132-F148 HydrophobicContact CG2-CZ 4.05Å; I132-A174 HydrophobicContact CG2-CB 3.68Å; I132-Q185 HydrophobicContact CG2-CB 3.86Å; I132-Q185 HydrophobicContact CG2-CG 4.32Å
133N94.9Very high95.6Very high47 Ų4742 Ų4225%0.25122%0.221SC..PPolyproline II helixtrans-72.3138.8176.2-57.3-70.7000111F148 S257 R261N133-F148 WeakPolarHBondContact O-CZ 3.29Å; N133-S257 PolarHBondContact OD1-OG 2.96Å; N133-R261 WeakPolarHBondContact ND2-CB 3.31Å; N133-R261 PolarHBondContact ND2-O 2.88Å
134C96.6Very high95.8Very high0 Ų035.5 Ų35.50%019%0.191CC..PPolyproline II helixtrans-68.5142.4172.8-73.70000112.5Q185 C187 Q195 C259 Y262C134-Q185 PolarHBondContact SG-NE2 2.82Å; C134-C187 WeakPolarHBondContact CA-SG 3.28Å; C134-C187 HydrophobicContact CB-CB 3.73Å; C134-C187 WeakPolarHBondContact CB-SG 3.38Å; C134-C187 WeakPolarHBondContact SG-CB 3.42Å; C134-C187 CovalentContact SG-SG 2.03Å; C134-C187 PolarHBondContact SG-SG 2.9Å; C134-Q195 PolarHBondContact SG-NE2 3.5Å; C134-Q195 VanDerWaalsContact SG-NE2 3.44Å; C134-C259 VanDerWaalsContact O-CB 3.25Å; C134-C259 WeakPolarHBondContact O-CB 3.48Å; C134-Y262 VanDerWaalsContact O-CB 3.28Å; C134-Y262 WeakPolarHBondContact O-CB 3.37Å
135P97.7Very high95.9Very high0 Ų035.9 Ų35.90%019%0.194CC..PPolyproline II helixtrans-52.8147.6166.3-22.930.9000112Q140 A141 F148 Y189 Y262P135-Q140 HydrophobicContact CB-CB 3.8Å; P135-A141 HydrophobicContact CB-CB 4.01Å; P135-A141 HydrophobicContact CG-CB 4.01Å; P135-F148 HydrophobicContact CG-CD2 3.88Å; P135-F148 HydrophobicContact CG-CE2 3.69Å; P135-F148 HydrophobicContact CG-CG 4.44Å; P135-F148 HydrophobicContact CG-CZ 4.1Å; P135-Y189 WeakPolarHBondContact CB-OH 3.36Å; P135-Y189 WeakPolarHBondContact CD-OH 3.16Å; P135-Y189 WeakPolarHBondContact O-CE1 3.33Å; P135-Y189 PolarHBondContact O-OH 2.89Å; P135-Y262 HydrophobicContact CB-CD1 4.36Å; P135-Y262 HydrophobicContact CB-CD2 4.39Å; P135-Y262 HydrophobicContact CB-CE1 3.96Å; P135-Y262 HydrophobicContact CB-CE2 4Å; P135-Y262 HydrophobicContact CG-CD2 4.21Å; P135-Y262 HydrophobicContact CG-CE1 4.49Å; P135-Y262 HydrophobicContact CG-CE2 3.65Å
136C96.8Very high96.1Very high6 Ų633.6 Ų33.64%0.04118%0.18CC..SBendtrans-76.9-25.3-177.3-77.80000113.1C259 V543 L563C136-C259 WeakPolarHBondContact CA-SG 3.35Å; C136-C259 HydrophobicContact CB-CB 3.77Å; C136-C259 WeakPolarHBondContact CB-SG 3.47Å; C136-C259 WeakPolarHBondContact SG-CB 3.29Å; C136-C259 PolarHBondContact SG-O 3.11Å; C136-C259 VanDerWaalsContact SG-O 3.34Å; C136-C259 CovalentContact SG-SG 2.04Å; C136-C259 PolarHBondContact SG-SG 2.93Å; C136-V543 HydrophobicContact CB-CG2 3.25Å; C136-L563 HydrophobicContact CB-CD2 4.07Å
137T97.6Very high96.2Very high26 Ų2630.4 Ų30.416%0.1616%0.16CC..BIsolated β-bridgetrans-131.6155.6-177.8720000111.6A139 Q140 A141 Y189 G193 V543 L563T137-A139 PolarHBondContact O-N 3.36Å; T137-Q140 PolarHBondContact O-N 2.94Å; T137-Q140 WeakPolarHBondContact OG1-CG 3.44Å; T137-Q140 PolarHBondContact OG1-N 3.39Å; T137-Q140 VanDerWaalsContact OG1-N 3.13Å; T137-A141 PolarHBondContact O-N 3.45Å; T137-Y189 VanDerWaalsContact C-CE1 3.47Å; T137-G193 CarbonylContact C-O 3.57Å; T137-G193 VanDerWaalsContact CA-O 3.3Å; T137-G193 WeakPolarHBondContact CA-O 3.49Å; T137-V543 HydrophobicContact CG2-CG1 4.4Å; T137-V543 HydrophobicContact CG2-CG2 4.36Å; T137-L563 HydrophobicContact CG2-CD1 3.93Å
138L97.6Very high96.3Very high23 Ų2330.6 Ų30.612%0.1216%0.161CC..Hα-helixtrans-58.9-34.3172.7177.955.8000112.4A141 R142 V169 H170 Y189 G193L138-A141 PolarHBondContact O-N 3.22Å; L138-R142 HydrophobicContact CD1-CG 4.07Å; L138-R142 WeakPolarHBondContact O-CG 3.44Å; L138-R142 PolarHBondContact O-N 3.38Å; L138-V169 HydrophobicContact CD2-CG2 4.32Å; L138-H170 HydrophobicContact CD1-CB 3.68Å; L138-H170 VanDerWaalsContact CD1-CD2 3.44Å; L138-H170 WeakPolarHBondContact CD1-CD2 3.43Å; L138-H170 HydrophobicContact CD2-CB 4.35Å; L138-Y189 HydrophobicContact CB-CD1 4.17Å; L138-Y189 HydrophobicContact CB-CD2 4.42Å; L138-Y189 HydrophobicContact CB-CG 3.88Å; L138-Y189 HydrophobicContact CD1-CD2 3.9Å; L138-Y189 HydrophobicContact CD1-CG 4.13Å; L138-G193 PolarHBondContact N-O 2.67Å
139A98.2Very high96.4Very high37 Ų3729.1 Ų29.131%0.30615%0.153SC..Hα-helixtrans-62.2-51.317600000111.1T137 A141 R142 A143 D539T137-A139 PolarHBondContact O-N 3.36Å; A139-A141 VanDerWaalsContact C-N 3.28Å; A139-A141 PolarHBondContact O-N 3Å; A139-R142 PolarHBondContact O-N 3.44Å; A139-A143 VanDerWaalsContact O-CB 3.32Å; A139-A143 WeakPolarHBondContact O-CB 3.42Å; A139-A143 PolarHBondContact O-N 3.41Å; A139-D539 HydrophobicContact CB-CB 4.14Å
140Q98.4Very high96.5Very high3 Ų326.2 Ų26.21%0.01414%0.135CC..Hα-helixtrans-58.6-41.2175-71174.1-24.100111.6P135 T137 R142 A143 D144 Y262 D539 K541P135-Q140 HydrophobicContact CB-CB 3.8Å; T137-Q140 PolarHBondContact O-N 2.94Å; T137-Q140 WeakPolarHBondContact OG1-CG 3.44Å; T137-Q140 PolarHBondContact OG1-N 3.39Å; T137-Q140 VanDerWaalsContact OG1-N 3.13Å; Q140-R142 VanDerWaalsContact C-N 3.33Å; Q140-R142 PolarHBondContact O-N 3.49Å; Q140-A143 PolarHBondContact O-N 2.93Å; Q140-D144 VanDerWaalsContact O-CB 3.32Å; Q140-D144 WeakPolarHBondContact O-CB 3.49Å; Q140-D144 PolarHBondContact O-N 3.44Å; Q140-Y262 HydrophobicContact CB-CE1 4.23Å; Q140-Y262 HydrophobicContact CG-CE1 4.46Å; Q140-D539 WeakPolarHBondContact CG-O 3.45Å; Q140-K541 PolarHBondContact NE2-O 2.87Å
141A97.9Very high96.6Very high2 Ų223.2 Ų23.22%0.01712%0.121CC..Hα-helixtrans-63.2-35.8-179.700000114.1P135 T137 L138 A139 V172 Y189P135-A141 HydrophobicContact CB-CB 4.01Å; P135-A141 HydrophobicContact CG-CB 4.01Å; T137-A141 PolarHBondContact O-N 3.45Å; L138-A141 PolarHBondContact O-N 3.22Å; A139-A141 VanDerWaalsContact C-N 3.28Å; A139-A141 PolarHBondContact O-N 3Å; A141-V172 HydrophobicContact CB-CG1 4.17Å; A141-V172 HydrophobicContact CB-CG2 3.98Å; A141-Y189 HydrophobicContact CB-CD2 4.29Å; A141-Y189 HydrophobicContact CB-CE1 4.43Å; A141-Y189 HydrophobicContact CB-CE2 3.43Å; A141-Y189 VanDerWaalsContact CB-CE2 3.43Å; A141-Y189 WeakPolarHBondContact CB-OH 3.42Å
142R97.2Very high96.3Very high123 Ų12329 Ų2946%0.46414%0.142SC..Hα-helixtrans-82-24176.8-67.9177.272.5-150.34.7112.7L138 A139 Q140 T145 E157L138-R142 HydrophobicContact CD1-CG 4.07Å; L138-R142 WeakPolarHBondContact O-CG 3.44Å; L138-R142 PolarHBondContact O-N 3.38Å; A139-R142 PolarHBondContact O-N 3.44Å; Q140-R142 VanDerWaalsContact C-N 3.33Å; Q140-R142 PolarHBondContact O-N 3.49Å; R142-T145 VanDerWaalsContact O-CG2 3.29Å; R142-T145 WeakPolarHBondContact O-CG2 3.47Å; R142-E157 IonicContact CZ-OE1 3.3Å; R142-E157 IonicContact NH2-OE1 2.54Å; R142-E157 PolarHBondContact NH2-OE1 3Å
143A98.3Very high96Very high5 Ų528.3 Ų28.34%0.04115%0.148CC..Hα-helixtrans-83.6-29.2178.500000113.4A139 Q140 T145 L402 L536 D539 L540A139-A143 VanDerWaalsContact O-CB 3.32Å; A139-A143 WeakPolarHBondContact O-CB 3.42Å; A139-A143 PolarHBondContact O-N 3.41Å; Q140-A143 PolarHBondContact O-N 2.93Å; A143-T145 PolarHBondContact O-N 2.5Å; A143-L402 WeakPolarHBondContact O-CD1 3.35Å; A143-L536 HydrophobicContact CB-CD1 3.68Å; A143-D539 HydrophobicContact CB-CB 3.85Å; A143-L540 HydrophobicContact CB-CD2 3.55Å; A143-L540 HydrophobicContact CB-CG 3.78Å
144D98.3Very high95.9Very high0 Ų026.1 Ų26.10%014%0.136CC..  trans-83.258.9-179.7-167.7-6.4000112.4Q140 G146 R147 F148 Y262 P265Q140-D144 VanDerWaalsContact O-CB 3.32Å; Q140-D144 WeakPolarHBondContact O-CB 3.49Å; Q140-D144 PolarHBondContact O-N 3.44Å; D144-G146 PolarHBondContact O-N 3.01Å; D144-R147 PolarHBondContact O-N 3.41Å; D144-R147 IonicContact OD1-CZ 3.74Å; D144-R147 IonicContact OD1-NE 2.73Å; D144-R147 PolarHBondContact OD1-NE 3.42Å; D144-R147 IonicContact OD1-NH2 3.41Å; D144-R147 IonicContact OD2-CZ 2.63Å; D144-R147 VanDerWaalsContact OD2-CZ 3.26Å; D144-R147 IonicContact OD2-NE 3.2Å; D144-R147 PolarHBondContact OD2-NE 3.17Å; D144-R147 VanDerWaalsContact OD2-NE 3.08Å; D144-R147 IonicContact OD2-NH2 2.64Å; D144-R147 PolarHBondContact OD2-NH2 3.42Å; D144-F148 HydrophobicContact CB-CD2 4.06Å; D144-F148 PolarHBondContact O-N 2.64Å; D144-Y262 WeakPolarHBondContact OD2-CE2 3.44Å; D144-Y262 PolarHBondContact OD2-OH 3.34Å; D144-P265 HydrophobicContact CB-CG 4.3Å
145T97Very high95.7Very high28 Ų2826.7 Ų26.717%0.17214%0.139CC..THydrogen-bonded Turntrans-72.7-6.5-174.261.90000113.8R142 A143 M381 E389 L402R142-T145 VanDerWaalsContact O-CG2 3.29Å; R142-T145 WeakPolarHBondContact O-CG2 3.47Å; A143-T145 PolarHBondContact O-N 2.5Å; T145-M381 WeakPolarHBondContact O-CG 3.44Å; T145-M381 VanDerWaalsContact O-SD 3.38Å; T145-E389 WeakPolarHBondContact CB-OE1 3.37Å; T145-E389 VanDerWaalsContact CG2-OE1 3.3Å; T145-E389 WeakPolarHBondContact CG2-OE1 3.44Å; T145-E389 PolarHBondContact OG1-OE1 3.12Å; T145-L402 WeakPolarHBondContact OG1-CD1 3.4Å
146G96.9Very high95.5Very high1 Ų130.2 Ų30.21%0.0116%0.157CC..THydrogen-bonded Turntrans-78.9-27.1172.900000113.7D144 G385D144-G146 PolarHBondContact O-N 3.01Å; G146-G385 CarbonylContact C-O 3.56Å
147R97.4Very high95.1Very high27 Ų2736.6 Ų36.610%0.10219%0.186CC..THydrogen-bonded Turntrans-119.2-25-174.6-63.7-176.7-62.3-176.90.5113.7I132 D144 A174 I175 Q263 P404I132-R147 HydrophobicContact CD1-CB 3.98Å; I132-R147 HydrophobicContact CD1-CG 4.29Å; D144-R147 PolarHBondContact O-N 3.41Å; D144-R147 IonicContact OD1-CZ 3.74Å; D144-R147 IonicContact OD1-NE 2.73Å; D144-R147 PolarHBondContact OD1-NE 3.42Å; D144-R147 IonicContact OD1-NH2 3.41Å; D144-R147 IonicContact OD2-CZ 2.63Å; D144-R147 VanDerWaalsContact OD2-CZ 3.26Å; D144-R147 IonicContact OD2-NE 3.2Å; D144-R147 PolarHBondContact OD2-NE 3.17Å; D144-R147 VanDerWaalsContact OD2-NE 3.08Å; D144-R147 IonicContact OD2-NH2 2.64Å; D144-R147 PolarHBondContact OD2-NH2 3.42Å; R147-A174 WeakPolarHBondContact O-CA 3.21Å; R147-I175 PolarHBondContact O-N 3.43Å; R147-Q263 PolarHBondContact NH1-O 3.04Å; R147-Q263 PolarHBondContact NH2-O 3.01Å; R147-P404 HydrophobicContact CG-CG 4.48Å
148F97.5Very high94.6Very high6 Ų643.4 Ų43.43%0.02621%0.213CC..EExtended strand (participates in β ladder)trans-123.5146-177.9-61.4-82.5000112.4I132 N133 P135 D144 V172 R173 A174 Y262I132-F148 HydrophobicContact CD1-CE2 4.06Å; I132-F148 HydrophobicContact CD1-CZ 3.78Å; I132-F148 HydrophobicContact CG1-CZ 4.09Å; I132-F148 HydrophobicContact CG2-CE1 4.1Å; I132-F148 HydrophobicContact CG2-CZ 4.05Å; N133-F148 WeakPolarHBondContact O-CZ 3.29Å; P135-F148 HydrophobicContact CG-CD2 3.88Å; P135-F148 HydrophobicContact CG-CE2 3.69Å; P135-F148 HydrophobicContact CG-CG 4.44Å; P135-F148 HydrophobicContact CG-CZ 4.1Å; D144-F148 HydrophobicContact CB-CD2 4.06Å; D144-F148 PolarHBondContact O-N 2.64Å; F148-V172 HydrophobicContact CB-CB 4.04Å; F148-V172 HydrophobicContact CB-CG2 3.85Å; F148-V172 HydrophobicContact CD1-CG2 3.76Å; F148-V172 HydrophobicContact CG-CG2 4Å; F148-R173 CarbonylContact C-O 3.49Å; F148-R173 VanDerWaalsContact CA-O 3.28Å; F148-R173 WeakPolarHBondContact CA-O 3.45Å; F148-A174 HydrophobicContact CE1-CB 4.44Å; F148-Y262 HydrophobicContact CE2-CE2 4.12Å
149H95.4Very high93.7Very high27 Ų2745 Ų4513%0.12524%0.235CC..EExtended strand (participates in β ladder)trans-132.3147.5175.2-177.5-78.5000109.8D151 V172 R173 I175 W213 F371H149-D151 PolarHBondContact O-N 3.29Å; H149-V172 CarbonylContact O-C 3.24Å; H149-V172 VanDerWaalsContact O-CA 3.23Å; H149-V172 WeakPolarHBondContact O-CA 3.26Å; H149-V172 WeakPolarHBondContact O-CB 3.37Å; H149-R173 PolarHBondContact N-O 2.97Å; H149-R173 PolarHBondContact O-N 2.63Å; H149-I175 HydrophobicContact CB-CD1 4.34Å; H149-I175 HydrophobicContact CB-CG1 3.71Å; H149-W213 HydrophobicContact CB-CH2 3.75Å; H149-W213 HydrophobicContact CB-CZ3 4.41Å; H149-W213 AromaticContact CG-CH2 3.72Å; H149-W213 AromaticContact ND1-CH2 3.68Å; H149-F371 AromaticContact NE2-CD1 3.93Å; H149-F371 AromaticContact NE2-CD2 3.53Å; H149-F371 AromaticContact NE2-CE1 3.97Å; H149-F371 AromaticContact NE2-CE2 3.58Å; H149-F371 AromaticContact NE2-CG 3.71Å; H149-F371 AromaticContact NE2-CZ 3.79Å
150T94.3Very high92.4Very high43 Ų4345 Ų4526%0.26423%0.234SC..EExtended strand (participates in β ladder)trans-53.7133.2177.8-59.20000112.1D155 H170T150-D155 HydrophobicContact CG2-CB 3.78Å; T150-H170 VanDerWaalsContact CG2-CE1 3.44Å; T150-H170 WeakPolarHBondContact CG2-CE1 3.41Å
151D93.2Very high91.5Very high6 Ų650.2 Ų50.23%0.03227%0.265CS..  trans-75.1124.8170.8-172.7-63.3000109.9H149 G153 C154 C171 R173 Q186H149-D151 PolarHBondContact O-N 3.29Å; D151-G153 PolarHBondContact O-N 2.98Å; D151-G153 VanDerWaalsContact OD1-CA 3.27Å; D151-G153 WeakPolarHBondContact OD1-CA 2.97Å; D151-G153 PolarHBondContact OD1-N 3.12Å; D151-C154 CarbonylContact O-C 3.57Å; D151-C154 PolarHBondContact O-N 2.03Å; D151-C154 PolarHBondContact OD1-N 3.44Å; D151-C171 HydrophobicContact CB-CB 3.75Å; D151-C171 VanDerWaalsContact CB-O 3.3Å; D151-C171 WeakPolarHBondContact CB-O 3.37Å; D151-C171 PolarHBondContact N-O 3.44Å; D151-R173 HydrophobicContact CB-CG 4.32Å; D151-R173 WeakPolarHBondContact OD2-CD 3.49Å; D151-R173 IonicContact OD2-CZ 3.22Å; D151-R173 IonicContact OD2-NE 2.83Å; D151-R173 PolarHBondContact OD2-NE 3.02Å; D151-R173 IonicContact OD2-NH2 3.81Å; D151-Q186 PolarHBondContact OD2-NE2 3.08Å
152Y87.4Confident91Very high149 Ų14950.8 Ų50.858%0.58427%0.269SS*.THydrogen-bonded Turntrans-68.8-21.1-177.156-97.8000113.7D212Y152-D212 VanDerWaalsContact CE1-OD2 3.26Å; Y152-D212 WeakPolarHBondContact CE1-OD2 3.36Å; Y152-D212 PolarHBondContact OH-OD1 2.83Å; Y152-D212 PolarHBondContact OH-OD2 2.93Å
153G87.1Confident90.4Very high36 Ų3649.3 Ų49.337%0.37127%0.274SS..THydrogen-bonded Turntrans-85.4-8.8175.200000114D151D151-G153 PolarHBondContact O-N 2.98Å; D151-G153 VanDerWaalsContact OD1-CA 3.27Å; D151-G153 WeakPolarHBondContact OD1-CA 2.97Å; D151-G153 PolarHBondContact OD1-N 3.12Å
154C93Very high89.7Confident0 Ų053.5 Ų53.50%029%0.289CS..SBendtrans-150.577178.4-1760000111.3D151 C162 H170 C171D151-C154 CarbonylContact O-C 3.57Å; D151-C154 PolarHBondContact O-N 2.03Å; D151-C154 PolarHBondContact OD1-N 3.44Å; C154-C162 VanDerWaalsContact CA-SG 3.55Å; C154-C162 HydrophobicContact CB-CB 3.76Å; C154-C162 WeakPolarHBondContact CB-SG 3.41Å; C154-C162 WeakPolarHBondContact SG-CB 3.3Å; C154-C162 CovalentContact SG-SG 2.03Å; C154-C162 PolarHBondContact SG-SG 2.83Å; C154-H170 WeakPolarHBondContact O-CA 3.45Å; C154-H170 PolarHBondContact O-ND1 2.86Å; C154-H170 VanDerWaalsContact SG-C 3.51Å; C154-H170 VanDerWaalsContact SG-CA 3.55Å; C154-C171 HydrophobicContact CB-CB 3.93Å; C154-C171 PolarHBondContact O-N 2.86Å; C154-C171 PolarHBondContact SG-N 3.28Å; C154-C171 PolarHBondContact SG-SG 2.69Å
155D93.1Very high89.3Confident13 Ų1354.5 Ų54.57%0.0729%0.294CS..  trans-117.2122.8-176.6-175.9-2.6000111.5T150 E157 K158 G159 S160 H170T150-D155 HydrophobicContact CG2-CB 3.78Å; D155-E157 VanDerWaalsContact C-N 3.33Å; D155-E157 PolarHBondContact O-N 3.38Å; D155-E157 PolarHBondContact OD1-N 2.75Å; D155-K158 HydrophobicContact CB-CB 4.28Å; D155-K158 HydrophobicContact CB-CD 4.48Å; D155-K158 PolarHBondContact O-N 3.42Å; D155-K158 WeakPolarHBondContact OD2-CD 3.4Å; D155-K158 WeakPolarHBondContact OD2-CE 3.47Å; D155-K158 WeakPolarHBondContact OD2-CG 3.4Å; D155-K158 IonicContact OD2-NZ 4Å; D155-G159 PolarHBondContact O-N 3.24Å; D155-S160 WeakPolarHBondContact O-CA 3.35Å; D155-S160 PolarHBondContact O-N 2.92Å; D155-H170 IonicContact OD1-CE1 2.75Å
156I93.1Very high89Confident73 Ų7355.8 Ų55.837%0.37430%0.302SS..G310 helixtrans-72.3-29.6-178-164.7171.3000112.1K158 G159 S160 V169 H170I156-K158 PolarHBondContact O-N 2.96Å; I156-G159 PolarHBondContact O-N 3.35Å; I156-S160 VanDerWaalsContact CA-OG 3.28Å; I156-S160 WeakPolarHBondContact CA-OG 3.28Å; I156-V169 HydrophobicContact CD1-CB 4.35Å; I156-V169 HydrophobicContact CD1-CG2 4.13Å; I156-H170 HydrophobicContact CB-CB 4.39Å; I156-H170 PolarHBondContact N-ND1 2.98Å
157E89Confident88.7Confident140 Ų14058.5 Ų58.565%0.65433%0.331SS*.G310 helixtrans-73.7-18-179.5-58.4-173173.600111.9R142 D155R142-E157 IonicContact CZ-OE1 3.3Å; R142-E157 IonicContact NH2-OE1 2.54Å; R142-E157 PolarHBondContact NH2-OE1 3Å; D155-E157 VanDerWaalsContact C-N 3.33Å; D155-E157 PolarHBondContact O-N 3.38Å; D155-E157 PolarHBondContact OD1-N 2.75Å
158K86.3Confident88.6Confident169 Ų16957.8 Ų57.874%0.73533%0.33SS*.G310 helixtrans-108.97.6178.8-63.6-180-174169.50114.3D155 I156D155-K158 HydrophobicContact CB-CB 4.28Å; D155-K158 HydrophobicContact CB-CD 4.48Å; D155-K158 PolarHBondContact O-N 3.42Å; D155-K158 WeakPolarHBondContact OD2-CD 3.4Å; D155-K158 WeakPolarHBondContact OD2-CE 3.47Å; D155-K158 WeakPolarHBondContact OD2-CG 3.4Å; D155-K158 IonicContact OD2-NZ 4Å; I156-K158 PolarHBondContact O-N 2.96Å
159G79.8Confident88.5Confident56 Ų5659 Ų5958%0.57734%0.337SS*.THydrogen-bonded Turntrans102.610.8173.500000116.8D155 I156D155-G159 PolarHBondContact O-N 3.24Å; I156-G159 PolarHBondContact O-N 3.35Å
160S69.3Low88.5Confident39 Ų3957.7 Ų57.727%0.27333%0.331SS..  trans48.676.2170.2-48.60000115.9D155 I156 V169D155-S160 WeakPolarHBondContact O-CA 3.35Å; D155-S160 PolarHBondContact O-N 2.92Å; I156-S160 VanDerWaalsContact CA-OG 3.28Å; I156-S160 WeakPolarHBondContact CA-OG 3.28Å; S160-V169 PolarHBondContact OG-O 2.9Å
161V79.9Confident88.7Confident111 Ų11155.6 Ų55.667%0.67332%0.319SS*.  trans-104.669.6166.5-168.30000109.5T163V161-T163 PolarHBondContact O-N 3.3Å; V161-T163 PolarHBondContact O-OG1 3.16Å
162C88.5Confident88.8Confident14 Ų1455.4 Ų55.410%0.09532%0.318CS..  trans-75.161.7-177.7-53.60000111.4C154 Y164 H165 S168C154-C162 VanDerWaalsContact CA-SG 3.55Å; C154-C162 HydrophobicContact CB-CB 3.76Å; C154-C162 WeakPolarHBondContact CB-SG 3.41Å; C154-C162 WeakPolarHBondContact SG-CB 3.3Å; C154-C162 CovalentContact SG-SG 2.03Å; C154-C162 PolarHBondContact SG-SG 2.83Å; C162-Y164 VanDerWaalsContact C-N 3.28Å; C162-Y164 PolarHBondContact O-N 3.39Å; C162-H165 HydrophobicContact CB-CB 4.23Å; C162-H165 CarbonylContact O-C 3.46Å; C162-H165 VanDerWaalsContact O-C 3.24Å; C162-H165 WeakPolarHBondContact O-CA 3.33Å; C162-H165 PolarHBondContact O-N 3.23Å; C162-S168 PolarHBondContact SG-O 3.41Å
163T83.6Confident89.3Confident93 Ų9349.1 Ų49.157%0.57129%0.293SS*.THydrogen-bonded Turntrans-53.2-42.4-168.2-58.20000113V161V161-T163 PolarHBondContact O-N 3.3Å; V161-T163 PolarHBondContact O-OG1 3.16Å
164Y83.1Confident89.7Confident92 Ų9247.6 Ų47.636%0.36128%0.277SS..THydrogen-bonded Turntrans-93.4-1-179.8-52.1-63.5000113.3C162 P166 F237 Y238 L242C162-Y164 VanDerWaalsContact C-N 3.28Å; C162-Y164 PolarHBondContact O-N 3.39Å; Y164-P166 VanDerWaalsContact C-CD 3.46Å; Y164-F237 HydrophobicContact CD1-CD1 4.29Å; Y164-F237 AromaticContact CD1-CE1 3.99Å; Y164-F237 HydrophobicContact CD1-CE1 3.99Å; Y164-Y238 HydrophobicContact CD1-CE1 4.42Å; Y164-Y238 AromaticContact CE1-CE1 3.66Å; Y164-Y238 HydrophobicContact CE1-CE1 3.66Å; Y164-Y238 PolarHBondContact OH-OH 3.25Å; Y164-L242 HydrophobicContact CD1-CD1 4.15Å; Y164-L242 HydrophobicContact CE1-CD1 3.99Å
165H90.9Very high89.8Confident21 Ų2148 Ų4810%0.09728%0.279CS..SBendtrans-128.262.7-178.1-55-72.9000111.7C162 G167 S168 Q186 C188C162-H165 HydrophobicContact CB-CB 4.23Å; C162-H165 CarbonylContact O-C 3.46Å; C162-H165 VanDerWaalsContact O-C 3.24Å; C162-H165 WeakPolarHBondContact O-CA 3.33Å; C162-H165 PolarHBondContact O-N 3.23Å; H165-G167 PolarHBondContact O-N 2.94Å; H165-S168 VanDerWaalsContact O-CB 3.26Å; H165-S168 WeakPolarHBondContact O-CB 3.3Å; H165-S168 PolarHBondContact O-N 3.42Å; H165-S168 PolarHBondContact O-OG 2.89Å; H165-Q186 PolarHBondContact CE1-OE1 3.02Å; H165-Q186 PolarHBondContact NE2-NE2 3.42Å; H165-Q186 VanDerWaalsContact NE2-NE2 3.13Å; H165-Q186 PolarHBondContact NE2-OE1 3.01Å; H165-C188 VanDerWaalsContact CG-SG 3.6Å
166P89.6Confident89.7Confident55 Ų5550.4 Ų50.436%0.35729%0.29SS..THydrogen-bonded Turntrans-58.7134.9179.925.8-35.9000111.6Y164 S168 I202Y164-P166 VanDerWaalsContact C-CD 3.46Å; P166-S168 VanDerWaalsContact C-N 3.31Å; P166-I202 HydrophobicContact CG-CD1 3.88Å; P166-I202 HydrophobicContact CG-CG1 3.57Å
167G90.3Very high89.8Confident59 Ų5947.6 Ų47.661%0.60828%0.278SS*.THydrogen-bonded Turntrans90.5-13.8-175.100000114.3H165 D190H165-G167 PolarHBondContact O-N 2.94Å; G167-D190 WeakPolarHBondContact O-CB 3.41Å
168S95.3Very high90Very high12 Ų1241.4 Ų41.48%0.08425%0.25CC..EExtended strand (participates in β ladder)trans-88.2148.5174.1-56.60000111.2C162 H165 P166 C188 Y189 V196 G203C162-S168 PolarHBondContact SG-O 3.41Å; H165-S168 VanDerWaalsContact O-CB 3.26Å; H165-S168 WeakPolarHBondContact O-CB 3.3Å; H165-S168 PolarHBondContact O-N 3.42Å; H165-S168 PolarHBondContact O-OG 2.89Å; P166-S168 VanDerWaalsContact C-N 3.31Å; S168-C188 WeakPolarHBondContact OG-CB 3.47Å; S168-Y189 CarbonylContact C-O 3.58Å; S168-Y189 VanDerWaalsContact CA-O 3.28Å; S168-Y189 WeakPolarHBondContact CA-O 3.3Å; S168-V196 WeakPolarHBondContact OG-CG2 3.48Å; S168-G203 PolarHBondContact OG-O 2.02Å
169V95.6Very high90.2Very high30 Ų3038.3 Ų38.318%0.18225%0.246CC..EExtended strand (participates in β ladder)trans-111.1-18.6172-59.40000112.3L138 I156 S160 Y189L138-V169 HydrophobicContact CD2-CG2 4.32Å; I156-V169 HydrophobicContact CD1-CB 4.35Å; I156-V169 HydrophobicContact CD1-CG2 4.13Å; S160-V169 PolarHBondContact OG-O 2.9Å; V169-Y189 PolarHBondContact N-O 2.8Å
170H97.3Very high90.8Very high0 Ų041.8 Ų41.80%025%0.246CC..EExtended strand (participates in β ladder)trans-154141.4179.7-16366.8000110.2L138 T150 C154 D155 I156 C188 Y189L138-H170 HydrophobicContact CD1-CB 3.68Å; L138-H170 VanDerWaalsContact CD1-CD2 3.44Å; L138-H170 WeakPolarHBondContact CD1-CD2 3.43Å; L138-H170 HydrophobicContact CD2-CB 4.35Å; T150-H170 VanDerWaalsContact CG2-CE1 3.44Å; T150-H170 WeakPolarHBondContact CG2-CE1 3.41Å; C154-H170 WeakPolarHBondContact O-CA 3.45Å; C154-H170 PolarHBondContact O-ND1 2.86Å; C154-H170 VanDerWaalsContact SG-C 3.51Å; C154-H170 VanDerWaalsContact SG-CA 3.55Å; D155-H170 IonicContact OD1-CE1 2.75Å; I156-H170 HydrophobicContact CB-CB 4.39Å; I156-H170 PolarHBondContact N-ND1 2.98Å; H170-C188 WeakPolarHBondContact O-CA 3.39Å; H170-Y189 PolarHBondContact N-O 2.8Å; H170-Y189 PolarHBondContact O-N 2.83Å
171C96.9Very high92Very high0 Ų041 Ų410%024%0.237CC..EExtended strand (participates in β ladder)trans-126.2151.4167.3-54.80000110.1D151 C154 Q186 C187 C188D151-C171 HydrophobicContact CB-CB 3.75Å; D151-C171 VanDerWaalsContact CB-O 3.3Å; D151-C171 WeakPolarHBondContact CB-O 3.37Å; D151-C171 PolarHBondContact N-O 3.44Å; C154-C171 HydrophobicContact CB-CB 3.93Å; C154-C171 PolarHBondContact O-N 2.86Å; C154-C171 PolarHBondContact SG-N 3.28Å; C154-C171 PolarHBondContact SG-SG 2.69Å; C171-Q186 HydrophobicContact CB-CG 4.24Å; C171-C187 CarbonylContact C-O 3.55Å; C171-C187 WeakPolarHBondContact CA-O 3.34Å; C171-C188 HydrophobicContact CB-CB 4.1Å; C171-C188 WeakPolarHBondContact CB-SG 3.45Å; C171-C188 VanDerWaalsContact SG-CA 3.58Å; C171-C188 WeakPolarHBondContact SG-CB 3.14Å; C171-C188 CovalentContact SG-SG 2.04Å; C171-C188 PolarHBondContact SG-SG 2.96Å
172V96.9Very high92.7Very high2 Ų235.7 Ų35.71%0.01221%0.205CC..EExtended strand (participates in β ladder)trans-122.2152.5168-57.40000109.2A141 F148 H149 Q186 C187 Y189A141-V172 HydrophobicContact CB-CG1 4.17Å; A141-V172 HydrophobicContact CB-CG2 3.98Å; F148-V172 HydrophobicContact CB-CB 4.04Å; F148-V172 HydrophobicContact CB-CG2 3.85Å; F148-V172 HydrophobicContact CD1-CG2 3.76Å; F148-V172 HydrophobicContact CG-CG2 4Å; H149-V172 CarbonylContact O-C 3.24Å; H149-V172 VanDerWaalsContact O-CA 3.23Å; H149-V172 WeakPolarHBondContact O-CA 3.26Å; H149-V172 WeakPolarHBondContact O-CB 3.37Å; V172-Q186 CarbonylContact O-C 3.36Å; V172-Q186 WeakPolarHBondContact O-CA 3.34Å; V172-C187 HydrophobicContact CG2-CB 3.86Å; V172-C187 PolarHBondContact N-O 2.73Å; V172-C187 PolarHBondContact O-N 3.34Å; V172-Y189 HydrophobicContact CG2-CE2 4.26Å
173R95.9Very high93Very high17 Ų1735 Ų356%0.06420%0.2CC..EExtended strand (participates in β ladder)trans-113.6145172.5-71.8177.8169.4-90.11.5109.7F148 H149 D151 I175 Q185 Q186 D208 H229F148-R173 CarbonylContact C-O 3.49Å; F148-R173 VanDerWaalsContact CA-O 3.28Å; F148-R173 WeakPolarHBondContact CA-O 3.45Å; H149-R173 PolarHBondContact N-O 2.97Å; H149-R173 PolarHBondContact O-N 2.63Å; D151-R173 HydrophobicContact CB-CG 4.32Å; D151-R173 WeakPolarHBondContact OD2-CD 3.49Å; D151-R173 IonicContact OD2-CZ 3.22Å; D151-R173 IonicContact OD2-NE 2.83Å; D151-R173 PolarHBondContact OD2-NE 3.02Å; D151-R173 IonicContact OD2-NH2 3.81Å; R173-I175 PolarHBondContact O-N 2.9Å; R173-Q185 CarbonylContact C-O 3.56Å; R173-Q185 VanDerWaalsContact CA-O 3.27Å; R173-Q185 WeakPolarHBondContact CA-O 3.34Å; R173-Q186 HydrophobicContact CG-CB 4.23Å; R173-Q186 HydrophobicContact CG-CG 3.95Å; R173-D208 IonicContact CZ-OD2 2.75Å; R173-D208 IonicContact NH1-OD2 3.87Å; R173-D208 PolarHBondContact NH1-OD2 2.91Å; R173-D208 IonicContact NH2-OD2 2.58Å; R173-H229 PolarHBondContact NH2-NE2 3.33Å
174A96Very high93.6Very high4 Ų430.7 Ų30.73%0.03317%0.174CC..EExtended strand (participates in β ladder)trans-56.2138163.700000108.6I132 R147 F148 Q185 H211I132-A174 HydrophobicContact CG2-CB 3.68Å; R147-A174 WeakPolarHBondContact O-CA 3.21Å; F148-A174 HydrophobicContact CE1-CB 4.44Å; A174-Q185 HydrophobicContact CB-CB 4.1Å; A174-Q185 PolarHBondContact N-O 2.79Å; A174-H211 PolarHBondContact O-NE2 2.77Å
175I94.9Very high94.2Very high7 Ų726.4 Ų26.44%0.03616%0.157CC..SBendtrans-75.5-35.8-179.3-67151.1000111R147 H149 R173 W213 F369 M381R147-I175 PolarHBondContact O-N 3.43Å; H149-I175 HydrophobicContact CB-CD1 4.34Å; H149-I175 HydrophobicContact CB-CG1 3.71Å; R173-I175 PolarHBondContact O-N 2.9Å; I175-W213 HydrophobicContact CB-CZ3 4.39Å; I175-W213 HydrophobicContact CG1-CZ3 4.37Å; I175-W213 HydrophobicContact CG2-CZ3 4.29Å; I175-F369 HydrophobicContact CG2-CB 3.71Å; I175-F369 HydrophobicContact CG2-CD1 3.94Å; I175-F369 HydrophobicContact CG2-CD2 4.06Å; I175-F369 HydrophobicContact CG2-CG 3.65Å; I175-M381 HydrophobicContact CD1-CB 4Å; I175-M381 HydrophobicContact CD1-CG 3.61Å; I175-M381 HydrophobicContact CD1-SD 3.21Å; I175-M381 WeakPolarHBondContact CD1-SD 3.15Å; I175-M381 HydrophobicContact CG1-SD 4.09Å; I175-M381 HydrophobicContact CG2-CB 4.37Å
176Q92.3Very high94.5Very high64 Ų6425.5 Ų25.530%0.29915%0.153SC..SBendtrans-105.9128.9-172-60.8-66.4-27.700110
177A94.3Very high94.9Very high15 Ų1522.9 Ų22.912%0.12414%0.136CC..  trans-70.3152.5170.200000111.4A183 H211A177-A183 CarbonylContact C-O 3.59Å; A177-A183 VanDerWaalsContact CA-O 3.28Å; A177-A183 WeakPolarHBondContact CA-O 3.42Å; A177-H211 HydrophobicContact CB-CB 3.49Å; A177-H211 VanDerWaalsContact CB-CB 3.49Å
178T94.1Very high95.2Very high10 Ų1020.1 Ų20.16%0.06111%0.107CC..  trans-65.9140176.669.80000111.3E130 I131 K180 A182 A183E130-T178 HydrophobicContact CB-CG2 3.66Å; E130-T178 WeakPolarHBondContact O-CG2 3.49Å; E130-T178 WeakPolarHBondContact OE2-CB 3.36Å; E130-T178 PolarHBondContact OE2-OG1 2.84Å; I131-T178 HydrophobicContact CD1-CG2 3.95Å; T178-K180 PolarHBondContact O-N 2.95Å; T178-A182 WeakPolarHBondContact O-CA 3.2Å; T178-A182 PolarHBondContact O-N 2.73Å; T178-A182 PolarHBondContact OG1-N 2.83Å; T178-A183 HydrophobicContact CG2-CB 4.09Å; T178-A183 PolarHBondContact N-O 3.25Å; T178-A183 PolarHBondContact OG1-N 2.92Å
179P90.3Very high95.2Very high103 Ų10319.5 Ų19.567%0.66910%0.103SC*.THydrogen-bonded Turntrans-65.5-39-170.723.4-33.6000113R223P179-R223 PolarHBondContact O-NH1 3.06Å; P179-R223 PolarHBondContact O-NH2 2.97Å
180K91.8Very high95.2Very high129 Ų12919.4 Ų19.456%0.56110%0.102SC*.THydrogen-bonded Turntrans-82.7-46.4-176.9-170.9-178.5175.6-169.40111.8E130 T178 R223E130-K180 WeakPolarHBondContact OE1-CB 3.19Å; E130-K180 WeakPolarHBondContact OE2-CB 3.49Å; E130-K180 PolarHBondContact OE2-N 2.76Å; T178-K180 PolarHBondContact O-N 2.95Å; K180-R223 PolarHBondContact O-NH2 3.48Å; K180-R223 VanDerWaalsContact O-NH2 3.09Å
181Y94.1Very high95.1Very high22 Ų2224.2 Ų24.29%0.08614%0.135CC..THydrogen-bonded Turntrans-101.3-11.3-170.6-61.1-65.3000115.2Y27 P125 F127 E130 A183 P222Y27-Y181 HydrophobicContact CD1-CD1 4.49Å; Y27-Y181 AromaticContact CE1-CD1 3.79Å; Y27-Y181 HydrophobicContact CE1-CD1 3.79Å; Y27-Y181 AromaticContact CZ-CD1 3.84Å; Y27-Y181 PolarHBondContact OH-O 2.83Å; P125-Y181 HydrophobicContact CB-CD1 4.24Å; P125-Y181 HydrophobicContact CB-CE1 3.44Å; P125-Y181 VanDerWaalsContact CB-CE1 3.44Å; P125-Y181 HydrophobicContact CG-CE1 4.26Å; F127-Y181 HydrophobicContact CB-CD1 4.38Å; F127-Y181 HydrophobicContact CB-CD2 3.92Å; F127-Y181 HydrophobicContact CB-CG 3.72Å; E130-Y181 HydrophobicContact CG-CD2 4.3Å; E130-Y181 HydrophobicContact CG-CE2 4.48Å; E130-Y181 VanDerWaalsContact OE2-CD2 3.25Å; E130-Y181 WeakPolarHBondContact OE2-CD2 3.48Å; E130-Y181 PolarHBondContact OE2-N 2.86Å; Y181-A183 PolarHBondContact O-N 2.94Å; Y181-P222 WeakPolarHBondContact O-CG 3.37Å
182A94.6Very high95Very high0 Ų027.8 Ų27.80%016%0.157CC..  trans56.633-171.200000113.4T178 H211 R223T178-A182 WeakPolarHBondContact O-CA 3.2Å; T178-A182 PolarHBondContact O-N 2.73Å; T178-A182 PolarHBondContact OG1-N 2.83Å; A182-H211 WeakPolarHBondContact O-CB 3.45Å; A182-H211 PolarHBondContact O-N 3.16Å; A182-R223 HydrophobicContact CB-CB 4.15Å; A182-R223 HydrophobicContact CB-CG 3.56Å
183A96.3Very high94.9Very high0 Ų028.4 Ų28.40%016%0.164CC..  trans-84.4155.4-178.500000111.5F127 I131 A177 T178 Y181 D208 R209F127-A183 HydrophobicContact CB-CB 4.06Å; F127-A183 HydrophobicContact CD2-CB 3.32Å; F127-A183 HydrophobicContact CE2-CB 4Å; F127-A183 HydrophobicContact CG-CB 4Å; I131-A183 HydrophobicContact CD1-CB 3.6Å; A177-A183 CarbonylContact C-O 3.59Å; A177-A183 VanDerWaalsContact CA-O 3.28Å; A177-A183 WeakPolarHBondContact CA-O 3.42Å; T178-A183 HydrophobicContact CG2-CB 4.09Å; T178-A183 PolarHBondContact N-O 3.25Å; T178-A183 PolarHBondContact OG1-N 2.92Å; Y181-A183 PolarHBondContact O-N 2.94Å; A183-D208 CarbonylContact C-O 3.49Å; A183-D208 VanDerWaalsContact CA-O 3.25Å; A183-D208 WeakPolarHBondContact CA-O 3.46Å; A183-D208 VanDerWaalsContact CB-O 3.24Å; A183-D208 WeakPolarHBondContact CB-O 3.3Å; A183-R209 WeakPolarHBondContact CA-O 3.33Å
184G95.8Very high94.9Very high2 Ų228.3 Ų28.32%0.02117%0.167CC..EExtended strand (participates in β ladder)trans-118.5170.5177.400000112.9I131 P207 D208I131-G184 WeakPolarHBondContact CD1-O 3.45Å; G184-P207 CarbonylContact O-C 3.44Å; G184-P207 WeakPolarHBondContact O-CA 3.46Å; G184-D208 PolarHBondContact N-O 3.03Å; G184-D208 PolarHBondContact O-N 3.31Å
185Q96.1Very high94.8Very high2 Ų229 Ų291%0.00917%0.169CC..EExtended strand (participates in β ladder)trans-132.1128.1172.7-178.760.135.700109.6I131 I132 C134 R173 A174 P207I131-Q185 HydrophobicContact CG2-CB 4.05Å; I131-Q185 HydrophobicContact CG2-CG 4.16Å; I132-Q185 HydrophobicContact CG2-CB 3.86Å; I132-Q185 HydrophobicContact CG2-CG 4.32Å; C134-Q185 PolarHBondContact SG-NE2 2.82Å; R173-Q185 CarbonylContact C-O 3.56Å; R173-Q185 VanDerWaalsContact CA-O 3.27Å; R173-Q185 WeakPolarHBondContact CA-O 3.34Å; A174-Q185 HydrophobicContact CB-CB 4.1Å; A174-Q185 PolarHBondContact N-O 2.79Å; Q185-P207 VanDerWaalsContact OE1-CA 3.25Å; Q185-P207 VanDerWaalsContact OE1-CB 3.26Å
186Q96.3Very high94.8Very high3 Ų329.4 Ų29.41%0.01417%0.172CC..EExtended strand (participates in β ladder)trans-110.4136169.1-166.4-161.551.100109.7D151 H165 C171 V172 R173 S205 T206D151-Q186 PolarHBondContact OD2-NE2 3.08Å; H165-Q186 PolarHBondContact CE1-OE1 3.02Å; H165-Q186 PolarHBondContact NE2-NE2 3.42Å; H165-Q186 VanDerWaalsContact NE2-NE2 3.13Å; H165-Q186 PolarHBondContact NE2-OE1 3.01Å; C171-Q186 HydrophobicContact CB-CG 4.24Å; V172-Q186 CarbonylContact O-C 3.36Å; V172-Q186 WeakPolarHBondContact O-CA 3.34Å; R173-Q186 HydrophobicContact CG-CB 4.23Å; R173-Q186 HydrophobicContact CG-CG 3.95Å; Q186-S205 CarbonylContact O-C 3.43Å; Q186-S205 WeakPolarHBondContact O-CB 3.49Å; Q186-T206 WeakPolarHBondContact CA-O 3.36Å; Q186-T206 WeakPolarHBondContact CB-O 3.04Å; Q186-T206 PolarHBondContact N-O 3.14Å; Q186-T206 PolarHBondContact O-N 3.33Å
187C96.9Very high94.9Very high0 Ų026.8 Ų26.80%016%0.16CC..EExtended strand (participates in β ladder)trans-127.4116.5-176.7-53.90000109.1C134 C171 V172 Y189C134-C187 WeakPolarHBondContact CA-SG 3.28Å; C134-C187 HydrophobicContact CB-CB 3.73Å; C134-C187 WeakPolarHBondContact CB-SG 3.38Å; C134-C187 WeakPolarHBondContact SG-CB 3.42Å; C134-C187 CovalentContact SG-SG 2.03Å; C134-C187 PolarHBondContact SG-SG 2.9Å; C171-C187 CarbonylContact C-O 3.55Å; C171-C187 WeakPolarHBondContact CA-O 3.34Å; V172-C187 HydrophobicContact CG2-CB 3.86Å; V172-C187 PolarHBondContact N-O 2.73Å; V172-C187 PolarHBondContact O-N 3.34Å; C187-Y189 HydrophobicContact CB-CE2 3.96Å; C187-Y189 WeakPolarHBondContact O-CE2 3.33Å
188C96.6Very high94.9Very high0 Ų026.7 Ų26.70%016%0.158CC..EExtended strand (participates in β ladder)trans-114.5142.9-174.7-66.30000111.6H165 S168 H170 C171 Q195 V196 S205H165-C188 VanDerWaalsContact CG-SG 3.6Å; S168-C188 WeakPolarHBondContact OG-CB 3.47Å; H170-C188 WeakPolarHBondContact O-CA 3.39Å; C171-C188 HydrophobicContact CB-CB 4.1Å; C171-C188 WeakPolarHBondContact CB-SG 3.45Å; C171-C188 VanDerWaalsContact SG-CA 3.58Å; C171-C188 WeakPolarHBondContact SG-CB 3.14Å; C171-C188 CovalentContact SG-SG 2.04Å; C171-C188 PolarHBondContact SG-SG 2.96Å; C188-Q195 WeakPolarHBondContact O-CA 3.33Å; C188-V196 PolarHBondContact O-N 2.82Å; C188-S205 PolarHBondContact N-OG 2.85Å; C188-S205 PolarHBondContact O-OG 2.9Å
189Y96.7Very high94.7Very high0 Ų028.9 Ų28.90%018%0.177CC..EExtended strand (participates in β ladder)trans-130.5142.3-173.4-54.2-91.3000111.5P135 T137 L138 A141 S168 V169 H170 V172 C187 A194 Q195P135-Y189 WeakPolarHBondContact CB-OH 3.36Å; P135-Y189 WeakPolarHBondContact CD-OH 3.16Å; P135-Y189 WeakPolarHBondContact O-CE1 3.33Å; P135-Y189 PolarHBondContact O-OH 2.89Å; T137-Y189 VanDerWaalsContact C-CE1 3.47Å; L138-Y189 HydrophobicContact CB-CD1 4.17Å; L138-Y189 HydrophobicContact CB-CD2 4.42Å; L138-Y189 HydrophobicContact CB-CG 3.88Å; L138-Y189 HydrophobicContact CD1-CD2 3.9Å; L138-Y189 HydrophobicContact CD1-CG 4.13Å; A141-Y189 HydrophobicContact CB-CD2 4.29Å; A141-Y189 HydrophobicContact CB-CE1 4.43Å; A141-Y189 HydrophobicContact CB-CE2 3.43Å; A141-Y189 VanDerWaalsContact CB-CE2 3.43Å; A141-Y189 WeakPolarHBondContact CB-OH 3.42Å; S168-Y189 CarbonylContact C-O 3.58Å; S168-Y189 VanDerWaalsContact CA-O 3.28Å; S168-Y189 WeakPolarHBondContact CA-O 3.3Å; V169-Y189 PolarHBondContact N-O 2.8Å; H170-Y189 PolarHBondContact N-O 2.8Å; H170-Y189 PolarHBondContact O-N 2.83Å; V172-Y189 HydrophobicContact CG2-CE2 4.26Å; C187-Y189 HydrophobicContact CB-CE2 3.96Å; C187-Y189 WeakPolarHBondContact O-CE2 3.33Å; Y189-A194 CarbonylContact C-O 3.57Å; Y189-A194 VanDerWaalsContact CA-O 3.27Å; Y189-A194 WeakPolarHBondContact CA-O 3.45Å; Y189-Q195 HydrophobicContact CD1-CB 4.21Å; Y189-Q195 HydrophobicContact CE1-CB 4.08Å; Y189-Q195 HydrophobicContact CE1-CG 4.35Å
190D95.1Very high94.7Very high28 Ų2826.3 Ų26.315%0.1516%0.158CC..EExtended strand (participates in β ladder)trans-78.2174.8174.873.318.1000112.2G167 T192 G193 A194 V196G167-D190 WeakPolarHBondContact O-CB 3.41Å; D190-T192 VanDerWaalsContact CG-OG1 3.31Å; D190-T192 PolarHBondContact O-N 2.84Å; D190-T192 VanDerWaalsContact OD1-CA 3.25Å; D190-T192 WeakPolarHBondContact OD1-CA 3.43Å; D190-T192 WeakPolarHBondContact OD1-CB 3.2Å; D190-T192 PolarHBondContact OD1-N 3.45Å; D190-T192 PolarHBondContact OD1-OG1 3.47Å; D190-T192 PolarHBondContact OD2-OG1 3.39Å; D190-G193 PolarHBondContact O-N 2.95Å; D190-G193 PolarHBondContact OD1-N 3.4Å; D190-G193 VanDerWaalsContact OD1-N 3.13Å; D190-A194 PolarHBondContact N-O 2.84Å; D190-A194 PolarHBondContact OD1-N 3.2Å; D190-V196 HydrophobicContact CB-CG2 3.99Å
191S94.1Very high94.7Very high100 Ų10022 Ų2270%0.69914%0.144SC*.THydrogen-bonded Turntrans-62.5-11.817960.10000114.5
192T94.9Very high94.4Very high76 Ų7625 Ų2547%0.46616%0.161SC..THydrogen-bonded Turntrans-96.20175.774.50000112.6D190 A194 R561D190-T192 VanDerWaalsContact CG-OG1 3.31Å; D190-T192 PolarHBondContact O-N 2.84Å; D190-T192 VanDerWaalsContact OD1-CA 3.25Å; D190-T192 WeakPolarHBondContact OD1-CA 3.43Å; D190-T192 WeakPolarHBondContact OD1-CB 3.2Å; D190-T192 PolarHBondContact OD1-N 3.45Å; D190-T192 PolarHBondContact OD1-OG1 3.47Å; D190-T192 PolarHBondContact OD2-OG1 3.39Å; T192-A194 VanDerWaalsContact C-N 3.31Å; T192-R561 PolarHBondContact OG1-NE 2.71Å; T192-R561 PolarHBondContact OG1-NH2 2.8Å
193G95.6Very high94.1Very high15 Ų1525 Ų2516%0.15516%0.161CC..SBendtrans80.29.6-179.700000113.8T137 L138 D190T137-G193 CarbonylContact C-O 3.57Å; T137-G193 VanDerWaalsContact CA-O 3.3Å; T137-G193 WeakPolarHBondContact CA-O 3.49Å; L138-G193 PolarHBondContact N-O 2.67Å; D190-G193 PolarHBondContact O-N 2.95Å; D190-G193 PolarHBondContact OD1-N 3.4Å; D190-G193 VanDerWaalsContact OD1-N 3.13Å
194A95.2Very high93.8Very high14 Ų1425 Ų2512%0.11616%0.161CC..BIsolated β-bridgetrans-86.1142.417700000110.5Y189 D190 T192 V196 R561Y189-A194 CarbonylContact C-O 3.57Å; Y189-A194 VanDerWaalsContact CA-O 3.27Å; Y189-A194 WeakPolarHBondContact CA-O 3.45Å; D190-A194 PolarHBondContact N-O 2.84Å; D190-A194 PolarHBondContact OD1-N 3.2Å; T192-A194 VanDerWaalsContact C-N 3.31Å; A194-V196 PolarHBondContact O-N 3.23Å; A194-R561 HydrophobicContact CB-CG 4.25Å
195Q95.2Very high93.6Very high18 Ų1825 Ų258%0.08416%0.16CC..BIsolated β-bridgetrans-62.2132.6174.9-167.3-171.12100110.7C134 C188 Y189 L197 S205 S257C134-Q195 PolarHBondContact SG-NE2 3.5Å; C134-Q195 VanDerWaalsContact SG-NE2 3.44Å; C188-Q195 WeakPolarHBondContact O-CA 3.33Å; Y189-Q195 HydrophobicContact CD1-CB 4.21Å; Y189-Q195 HydrophobicContact CE1-CB 4.08Å; Y189-Q195 HydrophobicContact CE1-CG 4.35Å; Q195-L197 HydrophobicContact CG-CD2 4.03Å; Q195-S205 WeakPolarHBondContact CG-OG 3.47Å; Q195-S257 PolarHBondContact NE2-O 2.86Å; Q195-S257 PolarHBondContact OE1-O 3.28Å
196V94.9Very high93.6Very high17 Ų1725.1 Ų25.110%0.10316%0.161CC..PPolyproline II helixtrans-88.4126.9172.5-170.70000108.3S168 C188 D190 A194 G204 S205S168-V196 WeakPolarHBondContact OG-CG2 3.48Å; C188-V196 PolarHBondContact O-N 2.82Å; D190-V196 HydrophobicContact CB-CG2 3.99Å; A194-V196 PolarHBondContact O-N 3.23Å; V196-G204 CarbonylContact O-C 3.56Å; V196-G204 WeakPolarHBondContact O-CA 3.46Å; V196-S205 PolarHBondContact O-N 2.88Å; V196-S205 PolarHBondContact O-OG 3.27Å
197L94.6Very high93.6Very high8 Ų825 Ų254%0.04216%0.161CC..BIsolated β-bridgetrans-107.6143-178-57.4-177.3000111.6Q195 A199 D200 S201 S256 W548 Y562Q195-L197 HydrophobicContact CG-CD2 4.03Å; L197-A199 PolarHBondContact O-N 2.73Å; L197-D200 PolarHBondContact O-N 2.85Å; L197-S201 PolarHBondContact O-N 3.4Å; L197-S256 WeakPolarHBondContact CA-OG 3.4Å; L197-W548 HydrophobicContact CD1-CB 3.91Å; L197-W548 HydrophobicContact CD1-CG 4.28Å; L197-Y562 HydrophobicContact CD1-CD2 3.77Å; L197-Y562 HydrophobicContact CD1-CE2 3.5Å; L197-Y562 VanDerWaalsContact CD1-CE2 3.5Å; L197-Y562 HydrophobicContact CG-CE2 4.34Å
198T93.5Very high93.5Very high13 Ų1325.1 Ų25.18%0.0816%0.161CC..THydrogen-bonded Turntrans-63-24.1178.952.50000112.9D200 S201 S205 T206 F251 S256T198-D200 PolarHBondContact O-N 2.88Å; T198-S201 WeakPolarHBondContact CA-O 3.36Å; T198-S205 WeakPolarHBondContact CG2-O 3.16Å; T198-T206 HydrophobicContact CG2-CG2 3.74Å; T198-F251 VanDerWaalsContact CB-CD1 3.44Å; T198-F251 HydrophobicContact CG2-CD1 3.35Å; T198-F251 HydrophobicContact CG2-CE1 3.51Å; T198-F251 HydrophobicContact CG2-CG 4.06Å; T198-F251 HydrophobicContact CG2-CZ 4.29Å; T198-S256 WeakPolarHBondContact CG2-OG 3.37Å; T198-S256 PolarHBondContact N-OG 3.12Å; T198-S256 PolarHBondContact OG1-N 2.87Å; T198-S256 VanDerWaalsContact OG1-N 3.09Å; T198-S256 PolarHBondContact OG1-OG 2.04Å
199A90.4Very high93.5Very high56 Ų5625.3 Ų25.346%0.46316%0.162SC..THydrogen-bonded Turntrans-75.1-10.8175.200000114L197 W548L197-A199 PolarHBondContact O-N 2.73Å; A199-W548 HydrophobicContact CB-CD2 4.07Å; A199-W548 HydrophobicContact CB-CG 4.45Å; A199-W548 HydrophobicContact CB-CH2 4.22Å; A199-W548 HydrophobicContact CB-CZ2 3.52Å
200D90.8Very high93.4Very high50 Ų5025.3 Ų25.327%0.26716%0.162SC..THydrogen-bonded Turntrans-119.4-26.2178.7-61.4-39.6000113.7L197 T198 W548 K557 T560 Y562L197-D200 PolarHBondContact O-N 2.85Å; T198-D200 PolarHBondContact O-N 2.88Å; D200-W548 PolarHBondContact OD1-NE1 3.35Å; D200-K557 WeakPolarHBondContact OD1-CE 3.37Å; D200-K557 IonicContact OD1-NZ 3.4Å; D200-K557 PolarHBondContact OD1-NZ 2.81Å; D200-K557 IonicContact OD2-NZ 2.79Å; D200-T560 HydrophobicContact CB-CG2 3.86Å; D200-Y562 PolarHBondContact OD1-OH 2.8Å; D200-Y562 VanDerWaalsContact OD1-OH 3.11Å; D200-Y562 WeakPolarHBondContact OD2-CE2 3.39Å; D200-Y562 VanDerWaalsContact OD2-CZ 3.29Å; D200-Y562 PolarHBondContact OD2-OH 3.08Å
201S90.7Very high93.5Very high37 Ų3724.2 Ų24.226%0.25916%0.156SC..  trans-148.9144.7-175.7177.40000110.9L197 T198 G203 G204L197-S201 PolarHBondContact O-N 3.4Å; T198-S201 WeakPolarHBondContact CA-O 3.36Å; S201-G203 PolarHBondContact O-N 2.84Å; S201-G203 PolarHBondContact OG-N 3.43Å; S201-G203 VanDerWaalsContact OG-N 3.1Å; S201-G204 PolarHBondContact O-N 3.29Å; S201-G204 VanDerWaalsContact O-N 3.17Å
202I89Confident93.4Very high87 Ų8719.8 Ų19.845%0.44612%0.124SC..THydrogen-bonded Turntrans-63.2-19.1171.665.9171.6000112.7P166 G204 C247 F251P166-I202 HydrophobicContact CG-CD1 3.88Å; P166-I202 HydrophobicContact CG-CG1 3.57Å; I202-G204 VanDerWaalsContact C-N 3.3Å; I202-C247 HydrophobicContact CG2-CB 4.3Å; I202-F251 HydrophobicContact CB-CE2 4.32Å; I202-F251 HydrophobicContact CB-CZ 4.19Å; I202-F251 HydrophobicContact CG2-CE2 4.19Å; I202-F251 WeakPolarHBondContact O-CZ 3.25Å
203G87.4Confident93.2Very high0 Ų017.3 Ų17.30%011%0.106CC..THydrogen-bonded Turntrans-91.117.217700000115.1S168 S201S168-G203 PolarHBondContact OG-O 2.02Å; S201-G203 PolarHBondContact O-N 2.84Å; S201-G203 PolarHBondContact OG-N 3.43Å; S201-G203 VanDerWaalsContact OG-N 3.1Å
204G90Very high93.1Very high0 Ų016.8 Ų16.80%010%0.101CC..  trans-63.1163.1-179.300000114.6V196 S201 I202V196-G204 CarbonylContact O-C 3.56Å; V196-G204 WeakPolarHBondContact O-CA 3.46Å; S201-G204 PolarHBondContact O-N 3.29Å; S201-G204 VanDerWaalsContact O-N 3.17Å; I202-G204 VanDerWaalsContact C-N 3.3Å
205S91.9Very high92.9Very high0 Ų016.7 Ų16.70%010%0.1CC..BIsolated β-bridgetrans-62.1131.3172.3-56.30000110.6Q186 C188 Q195 V196 T198 S256Q186-S205 CarbonylContact O-C 3.43Å; Q186-S205 WeakPolarHBondContact O-CB 3.49Å; C188-S205 PolarHBondContact N-OG 2.85Å; C188-S205 PolarHBondContact O-OG 2.9Å; Q195-S205 WeakPolarHBondContact CG-OG 3.47Å; V196-S205 PolarHBondContact O-N 2.88Å; V196-S205 PolarHBondContact O-OG 3.27Å; T198-S205 WeakPolarHBondContact CG2-O 3.16Å; S205-S256 VanDerWaalsContact O-CA 3.3Å; S205-S256 WeakPolarHBondContact O-CA 3.36Å; S205-S256 VanDerWaalsContact O-CB 3.3Å; S205-S256 WeakPolarHBondContact O-CB 3.34Å; S205-S256 PolarHBondContact O-OG 2.85Å
206T95Very high92.4Very high6 Ų619.5 Ų19.54%0.03712%0.119CC..  trans-122.8137.8-178.252.70000111.8Q186 T198 Y250 F251 R254Q186-T206 WeakPolarHBondContact CA-O 3.36Å; Q186-T206 WeakPolarHBondContact CB-O 3.04Å; Q186-T206 PolarHBondContact N-O 3.14Å; Q186-T206 PolarHBondContact O-N 3.33Å; T198-T206 HydrophobicContact CG2-CG2 3.74Å; T206-Y250 HydrophobicContact CG2-CE1 3.95Å; T206-F251 HydrophobicContact CG2-CE1 4.48Å; T206-R254 HydrophobicContact CG2-CB 4.44Å
207P96.3Very high92Very high1 Ų122.6 Ų22.61%0.00614%0.14CC..EExtended strand (participates in β ladder)trans-71.1150.6157.933.7-33.8000108.2F127 L128 I131 G184 Q185 R254 P255F127-P207 HydrophobicContact CE2-CB 3.97Å; F127-P207 HydrophobicContact CZ-CB 4.49Å; L128-P207 HydrophobicContact CD2-CB 3.76Å; L128-P207 HydrophobicContact CD2-CG 3.45Å; L128-P207 VanDerWaalsContact CD2-CG 3.45Å; I131-P207 HydrophobicContact CD1-CB 4.4Å; I131-P207 HydrophobicContact CG1-CB 4.2Å; I131-P207 HydrophobicContact CG2-CB 4.33Å; G184-P207 CarbonylContact O-C 3.44Å; G184-P207 WeakPolarHBondContact O-CA 3.46Å; Q185-P207 VanDerWaalsContact OE1-CA 3.25Å; Q185-P207 VanDerWaalsContact OE1-CB 3.26Å; P207-R254 WeakPolarHBondContact O-CD 3.48Å; P207-P255 WeakPolarHBondContact CD-O 3.05Å; P207-P255 WeakPolarHBondContact CG-O 3.37Å
208D95.9Very high91.5Very high2 Ų226.3 Ų26.31%0.01116%0.156CC..EExtended strand (participates in β ladder)trans-117.3133.6179-59.9-40.7000109.1F127 R173 A183 G184 A210 H229F127-D208 WeakPolarHBondContact CE2-O 3.12Å; R173-D208 IonicContact CZ-OD2 2.75Å; R173-D208 IonicContact NH1-OD2 3.87Å; R173-D208 PolarHBondContact NH1-OD2 2.91Å; R173-D208 IonicContact NH2-OD2 2.58Å; A183-D208 CarbonylContact C-O 3.49Å; A183-D208 VanDerWaalsContact CA-O 3.25Å; A183-D208 WeakPolarHBondContact CA-O 3.46Å; A183-D208 VanDerWaalsContact CB-O 3.24Å; A183-D208 WeakPolarHBondContact CB-O 3.3Å; G184-D208 PolarHBondContact N-O 3.03Å; G184-D208 PolarHBondContact O-N 3.31Å; D208-A210 VanDerWaalsContact C-N 3.26Å; D208-A210 WeakPolarHBondContact CB-O 3.13Å; D208-A210 PolarHBondContact O-N 3.34Å; D208-H229 IonicContact OD1-CE1 2.82Å; D208-H229 PolarHBondContact OD1-CE1 3.19Å; D208-H229 IonicContact OD2-CE1 3.77Å
209R95.8Very high91.2Very high4 Ų434.2 Ų34.22%0.01519%0.189CC..SBendtrans-65.1-38.2177.2171.4174-65.5-74.61.4110.8E121 P125 F127 A183 Y232 D233 R254E121-R209 VanDerWaalsContact CD-NH2 3.33Å; E121-R209 IonicContact OE1-CZ 3.62Å; E121-R209 IonicContact OE1-NE 3.14Å; E121-R209 PolarHBondContact OE1-NE 3.4Å; E121-R209 IonicContact OE1-NH2 3.39Å; E121-R209 IonicContact OE2-CZ 2.64Å; E121-R209 IonicContact OE2-NE 2.76Å; E121-R209 PolarHBondContact OE2-NE 3.19Å; E121-R209 IonicContact OE2-NH2 2.76Å; E121-R209 PolarHBondContact OE2-NH2 2.96Å; P125-R209 PolarHBondContact O-NH1 3.48Å; F127-R209 HydrophobicContact CD1-CB 4.16Å; F127-R209 HydrophobicContact CD1-CG 4.32Å; F127-R209 HydrophobicContact CE1-CB 3.77Å; F127-R209 HydrophobicContact CE1-CG 4.39Å; F127-R209 HydrophobicContact CZ-CB 4.01Å; A183-R209 WeakPolarHBondContact CA-O 3.33Å; R209-Y232 HydrophobicContact CG-CG 4.44Å; R209-D233 PolarHBondContact N-OD1 3.49Å; R209-D233 PolarHBondContact N-OD2 2.91Å; R209-D233 VanDerWaalsContact N-OD2 3.12Å; R209-R254 VanDerWaalsContact CB-NH2 3.32Å
210A95.8Very high91.2Very high0 Ų035.4 Ų35.40%018%0.184CC..SBendtrans-114.1120.9175.800000108.5D208 D212 P222 S228 H229 Y232 D233D208-A210 VanDerWaalsContact C-N 3.26Å; D208-A210 WeakPolarHBondContact CB-O 3.13Å; D208-A210 PolarHBondContact O-N 3.34Å; A210-D212 PolarHBondContact O-N 2.78Å; A210-P222 HydrophobicContact CB-CB 4.01Å; A210-P222 VanDerWaalsContact CB-O 3.29Å; A210-P222 WeakPolarHBondContact CB-O 3.26Å; A210-S228 WeakPolarHBondContact CB-O 3.32Å; A210-H229 HydrophobicContact CB-CB 4.37Å; A210-H229 PolarHBondContact O-ND1 2.98Å; A210-H229 VanDerWaalsContact O-ND1 3.13Å; A210-Y232 HydrophobicContact CB-CD2 4.39Å; A210-D233 PolarHBondContact N-OD2 3.43Å
211H95.7Very high91.4Very high4 Ų433.5 Ų33.52%0.01917%0.174CC..  trans-60.1132.9174.1-169.2-81.5000110A174 A177 A182 W213 G214A174-H211 PolarHBondContact O-NE2 2.77Å; A177-H211 HydrophobicContact CB-CB 3.49Å; A177-H211 VanDerWaalsContact CB-CB 3.49Å; A182-H211 WeakPolarHBondContact O-CB 3.45Å; A182-H211 PolarHBondContact O-N 3.16Å; H211-W213 VanDerWaalsContact C-N 3.3Å; H211-W213 AromaticContact CE1-CE3 3.76Å; H211-W213 PolarHBondContact ND1-N 3.36Å; H211-W213 VanDerWaalsContact ND1-N 3.15Å; H211-W213 PolarHBondContact O-N 3.49Å; H211-G214 WeakPolarHBondContact O-CA 3.42Å; H211-G214 PolarHBondContact O-N 3.29Å
212D93.1Very high91.6Very high7 Ų731.8 Ų31.84%0.03716%0.162CC..THydrogen-bonded Turntrans-56.9-40.6-176.1178.758.2000112.9Y152 A210 G214 G226 H229Y152-D212 VanDerWaalsContact CE1-OD2 3.26Å; Y152-D212 WeakPolarHBondContact CE1-OD2 3.36Å; Y152-D212 PolarHBondContact OH-OD1 2.83Å; Y152-D212 PolarHBondContact OH-OD2 2.93Å; A210-D212 PolarHBondContact O-N 2.78Å; D212-G214 PolarHBondContact O-N 2.74Å; D212-G226 PolarHBondContact O-N 2.66Å; D212-H229 HydrophobicContact CB-CB 4.43Å; D212-H229 IonicContact OD1-CD2 2.68Å; D212-H229 PolarHBondContact OD1-CD2 3.06Å; D212-H229 VanDerWaalsContact OD1-CD2 3.29Å; D212-H229 IonicContact OD1-CG 3.11Å
213W91.6Very high91.8Very high24 Ų2429.3 Ų29.39%0.09115%0.147CC..THydrogen-bonded Turntrans-82.14.2174.7-53.8-25.9000114.6H149 I175 H211 P225 W362 F369H149-W213 HydrophobicContact CB-CH2 3.75Å; H149-W213 HydrophobicContact CB-CZ3 4.41Å; H149-W213 AromaticContact CG-CH2 3.72Å; H149-W213 AromaticContact ND1-CH2 3.68Å; I175-W213 HydrophobicContact CB-CZ3 4.39Å; I175-W213 HydrophobicContact CG1-CZ3 4.37Å; I175-W213 HydrophobicContact CG2-CZ3 4.29Å; H211-W213 VanDerWaalsContact C-N 3.3Å; H211-W213 AromaticContact CE1-CE3 3.76Å; H211-W213 PolarHBondContact ND1-N 3.36Å; H211-W213 VanDerWaalsContact ND1-N 3.15Å; H211-W213 PolarHBondContact O-N 3.49Å; W213-P225 WeakPolarHBondContact O-CB 3.42Å; W213-P225 WeakPolarHBondContact O-CG 3.3Å; W213-W362 HydrophobicContact CG-CH2 4.36Å; W213-F369 HydrophobicContact CD2-CE2 4.39Å; W213-F369 HydrophobicContact CE3-CD2 4.45Å; W213-F369 AromaticContact CE3-CE2 3.68Å; W213-F369 HydrophobicContact CE3-CE2 3.68Å; W213-F369 HydrophobicContact CE3-CZ 4.04Å; W213-F369 HydrophobicContact CH2-CE2 4.42Å; W213-F369 AromaticContact CH2-CZ 3.94Å; W213-F369 HydrophobicContact CH2-CZ 3.94Å; W213-F369 HydrophobicContact CZ3-CD2 4.47Å; W213-F369 HydrophobicContact CZ3-CE1 4.33Å; W213-F369 AromaticContact CZ3-CE2 3.69Å; W213-F369 HydrophobicContact CZ3-CE2 3.69Å; W213-F369 AromaticContact CZ3-CZ 3.61Å; W213-F369 HydrophobicContact CZ3-CZ 3.61Å
214G92.3Very high92.2Very high5 Ų530.1 Ų30.15%0.05215%0.151CC..  trans71.2-163.5-174.700000113.1H211 D212 R223H211-G214 WeakPolarHBondContact O-CA 3.42Å; H211-G214 PolarHBondContact O-N 3.29Å; D212-G214 PolarHBondContact O-N 2.74Å; G214-R223 WeakPolarHBondContact CA-O 3.43Å
215S90.4Very high92.3Very high12 Ų1232.6 Ų32.68%0.08417%0.167CC..  trans-157.3145.3177.7-173.60000111.1P217 F218 R223S215-P217 CarbonylContact O-C 3.6Å; S215-P217 VanDerWaalsContact O-C 3.25Å; S215-F218 PolarHBondContact O-N 3.04Å; S215-R223 PolarHBondContact N-O 3.47Å; S215-R223 WeakPolarHBondContact O-CB 3.36Å; S215-R223 PolarHBondContact OG-NH1 2.95Å; S215-R223 VanDerWaalsContact OG-NH1 3.08Å
216P85.3Confident92.3Very high76 Ų7633.3 Ų33.349%0.49418%0.175SC..SBendtrans-60.1145.4168.7-23.733.6000112.6F218 R223P216-F218 HydrophobicContact CB-CE2 4.41Å; P216-F218 HydrophobicContact CG-CD2 4.44Å; P216-F218 HydrophobicContact CG-CE2 3.74Å; P216-F218 HydrophobicContact CG-CZ 3.79Å; P216-R223 PolarHBondContact O-NH1 2.9Å
217P86.5Confident92.3Very high83 Ų8334.7 Ų34.754%0.53918%0.181SC..SBendcis-69.1123.6-14.230.2-33000110.4S215S215-P217 CarbonylContact O-C 3.6Å; S215-P217 VanDerWaalsContact O-C 3.25Å
218F84.4Confident92.3Very high85 Ų8534.7 Ų34.737%0.37318%0.181SC..THydrogen-bonded Turntrans-61.5158.8175.2-58.3-71.3000110.5S215 P216 P225 D364S215-F218 PolarHBondContact O-N 3.04Å; P216-F218 HydrophobicContact CB-CE2 4.41Å; P216-F218 HydrophobicContact CG-CD2 4.44Å; P216-F218 HydrophobicContact CG-CE2 3.74Å; P216-F218 HydrophobicContact CG-CZ 3.79Å; F218-P225 HydrophobicContact CD1-CG 3.68Å; F218-P225 HydrophobicContact CE1-CG 4.07Å; F218-D364 WeakPolarHBondContact CZ-OD2 3.43Å
219K86.3Confident92.3Very high179 Ų17935.1 Ų35.178%0.77818%0.182SC*.THydrogen-bonded Turntrans79.74.2-179.4-47.2175.1-179.6-178.80116.2
220K91.8Very high92.2Very high82 Ų8236.8 Ų36.836%0.35719%0.189SC..SBendtrans-112.7126.1168.3-73.8-169.5167.6-171.60109.1E29 R223E29-K220 IonicContact OE1-NZ 3.57Å; E29-K220 PolarHBondContact OE1-NZ 2.74Å; E29-K220 IonicContact OE2-NZ 3.72Å; E29-K220 PolarHBondContact OE2-NZ 2.87Å; K220-R223 VanDerWaalsContact O-CA 3.25Å; K220-R223 WeakPolarHBondContact O-CA 3.46Å; K220-R223 WeakPolarHBondContact O-CB 3.37Å; K220-R223 VanDerWaalsContact O-CG 3.24Å; K220-R223 WeakPolarHBondContact O-CG 3.46Å; K220-R223 PolarHBondContact O-N 2.89Å
221P94.4Very high92.2Very high9 Ų938.4 Ų38.46%0.05820%0.199CC..THydrogen-bonded Turntrans-49.5145166.9-36.343.3000114E22 W31 I224E22-P221 HydrophobicContact CB-CG 4.11Å; E22-P221 VanDerWaalsContact CD-CG 3.45Å; E22-P221 HydrophobicContact CG-CB 4.42Å; E22-P221 HydrophobicContact CG-CG 3.81Å; E22-P221 WeakPolarHBondContact OE2-CB 3.42Å; E22-P221 WeakPolarHBondContact OE2-CG 3.49Å; W31-P221 HydrophobicContact CB-CB 4.47Å; W31-P221 HydrophobicContact CD2-CB 3.33Å; W31-P221 HydrophobicContact CD2-CG 4.34Å; W31-P221 HydrophobicContact CE3-CB 3.8Å; W31-P221 VanDerWaalsContact CE3-O 3.23Å; W31-P221 HydrophobicContact CG-CB 3.6Å; W31-P221 HydrophobicContact CG-CG 4.11Å; W31-P221 HydrophobicContact CZ2-CB 4.03Å; W31-P221 HydrophobicContact CZ3-CB 4.4Å; P221-I224 HydrophobicContact CG-CD1 3.98Å
222P94.1Very high92.1Very high1 Ų138.9 Ų38.91%0.00620%0.201CC..THydrogen-bonded Turncis-91.235.6-5.538.5-28.4000110.6Y27 W31 Y181 A210 S228 Y232Y27-P222 HydrophobicContact CE1-CG 4.12Å; W31-P222 HydrophobicContact CH2-CB 3.96Å; W31-P222 HydrophobicContact CH2-CG 3.93Å; W31-P222 HydrophobicContact CZ2-CB 4.45Å; W31-P222 HydrophobicContact CZ3-CB 4.44Å; W31-P222 VanDerWaalsContact CZ3-CD 3.45Å; W31-P222 HydrophobicContact CZ3-CG 4.07Å; Y181-P222 WeakPolarHBondContact O-CG 3.37Å; A210-P222 HydrophobicContact CB-CB 4.01Å; A210-P222 VanDerWaalsContact CB-O 3.29Å; A210-P222 WeakPolarHBondContact CB-O 3.26Å; P222-S228 WeakPolarHBondContact CA-OG 3.5Å; P222-S228 VanDerWaalsContact O-CB 3.22Å; P222-S228 WeakPolarHBondContact O-CB 3.47Å; P222-Y232 HydrophobicContact CB-CD2 4.1Å; P222-Y232 HydrophobicContact CB-CE2 4.03Å
223R94.3Very high92.2Very high36 Ų3638.7 Ų38.714%0.13620%0.199CC..  trans-10210.1-172.2-34.7-169.1161.8-113.9-10.1113.9P179 K180 A182 G214 S215 P216 K220 P225P179-R223 PolarHBondContact O-NH1 3.06Å; P179-R223 PolarHBondContact O-NH2 2.97Å; K180-R223 PolarHBondContact O-NH2 3.48Å; K180-R223 VanDerWaalsContact O-NH2 3.09Å; A182-R223 HydrophobicContact CB-CB 4.15Å; A182-R223 HydrophobicContact CB-CG 3.56Å; G214-R223 WeakPolarHBondContact CA-O 3.43Å; S215-R223 PolarHBondContact N-O 3.47Å; S215-R223 WeakPolarHBondContact O-CB 3.36Å; S215-R223 PolarHBondContact OG-NH1 2.95Å; S215-R223 VanDerWaalsContact OG-NH1 3.08Å; P216-R223 PolarHBondContact O-NH1 2.9Å; K220-R223 VanDerWaalsContact O-CA 3.25Å; K220-R223 WeakPolarHBondContact O-CA 3.46Å; K220-R223 WeakPolarHBondContact O-CB 3.37Å; K220-R223 VanDerWaalsContact O-CG 3.24Å; K220-R223 WeakPolarHBondContact O-CG 3.46Å; K220-R223 PolarHBondContact O-N 2.89Å; R223-P225 WeakPolarHBondContact O-CD 2.92Å
224I94.9Very high92.3Very high17 Ų1738.5 Ų38.59%0.08720%0.201CC..SBendtrans-81117.3-177.6-57.3-175.8000108Y20 P221 G226 Q227 S228Y20-I224 WeakPolarHBondContact OH-CD1 3.19Å; P221-I224 HydrophobicContact CG-CD1 3.98Å; I224-G226 PolarHBondContact O-N 3.39Å; I224-Q227 HydrophobicContact CG2-CB 4.11Å; I224-Q227 PolarHBondContact O-N 2.9Å; I224-S228 WeakPolarHBondContact CB-OG 3.48Å; I224-S228 PolarHBondContact N-OG 2.92Å; I224-S228 VanDerWaalsContact N-OG 3.09Å; I224-S228 PolarHBondContact O-N 3.43Å; I224-S228 VanDerWaalsContact O-N 3.12Å
225P92.8Very high92.4Very high52 Ų5238.7 Ų38.734%0.33820%0.201SC..THydrogen-bonded Turntrans-55.9130.4-175.7-25.234.2000112.3W213 F218 R223 Q227W213-P225 WeakPolarHBondContact O-CB 3.42Å; W213-P225 WeakPolarHBondContact O-CG 3.3Å; F218-P225 HydrophobicContact CD1-CG 3.68Å; F218-P225 HydrophobicContact CE1-CG 4.07Å; R223-P225 WeakPolarHBondContact O-CD 2.92Å; P225-Q227 PolarHBondContact O-N 3.42Å; P225-Q227 PolarHBondContact O-NE2 3.26Å; P225-Q227 PolarHBondContact O-OE1 2.9Å
226G92.2Very high92.6Very high15 Ų1538.2 Ų38.216%0.15520%0.197CC..THydrogen-bonded Turntrans73.5-58.8-175.700000112.9D212 I224 S228 H229 W230D212-G226 PolarHBondContact O-N 2.66Å; I224-G226 PolarHBondContact O-N 3.39Å; G226-S228 PolarHBondContact O-N 3.41Å; G226-H229 WeakPolarHBondContact O-CB 3.26Å; G226-H229 PolarHBondContact O-N 3.45Å; G226-W230 PolarHBondContact O-N 3.24Å
227Q94.6Very high93Very high35 Ų3535.4 Ų35.416%0.16418%0.177CC..Hα-helixtrans-67.5-42.5-167.7-70.780.158.300113.9Y20 W35 D91 I224 P225 H229 W230 V231Y20-Q227 HydrophobicContact CD1-CB 3.81Å; Y20-Q227 HydrophobicContact CD1-CG 4.18Å; Y20-Q227 HydrophobicContact CD2-CB 4.23Å; Y20-Q227 HydrophobicContact CD2-CG 4.02Å; Y20-Q227 HydrophobicContact CE1-CB 3.44Å; Y20-Q227 VanDerWaalsContact CE1-CB 3.44Å; Y20-Q227 HydrophobicContact CE1-CG 4.23Å; Y20-Q227 HydrophobicContact CE2-CB 3.92Å; Y20-Q227 HydrophobicContact CE2-CG 4.08Å; Y20-Q227 HydrophobicContact CG-CB 4.12Å; Y20-Q227 HydrophobicContact CG-CG 4Å; Y20-Q227 VanDerWaalsContact CZ-CB 3.46Å; W35-Q227 HydrophobicContact CZ2-CG 3.67Å; D91-Q227 PolarHBondContact OD2-NE2 3.01Å; I224-Q227 HydrophobicContact CG2-CB 4.11Å; I224-Q227 PolarHBondContact O-N 2.9Å; P225-Q227 PolarHBondContact O-N 3.42Å; P225-Q227 PolarHBondContact O-NE2 3.26Å; P225-Q227 PolarHBondContact O-OE1 2.9Å; Q227-H229 VanDerWaalsContact C-N 3.3Å; Q227-H229 PolarHBondContact O-N 3.03Å; Q227-W230 WeakPolarHBondContact O-CB 3.4Å; Q227-W230 PolarHBondContact O-N 3.48Å; Q227-V231 WeakPolarHBondContact O-CG2 3.39Å; Q227-V231 PolarHBondContact O-N 3.22Å
228S95.9Very high93.3Very high0 Ų032.8 Ų32.80%016%0.157CC..Hα-helixtrans-64.7-37.8177.9-63.90000111.2E22 A210 P222 I224 G226 W230 V231 Y232E22-S228 WeakPolarHBondContact OE1-CA 3.35Å; E22-S228 WeakPolarHBondContact OE1-CB 3.12Å; E22-S228 PolarHBondContact OE1-OG 3.25Å; A210-S228 WeakPolarHBondContact CB-O 3.32Å; P222-S228 WeakPolarHBondContact CA-OG 3.5Å; P222-S228 VanDerWaalsContact O-CB 3.22Å; P222-S228 WeakPolarHBondContact O-CB 3.47Å; I224-S228 WeakPolarHBondContact CB-OG 3.48Å; I224-S228 PolarHBondContact N-OG 2.92Å; I224-S228 VanDerWaalsContact N-OG 3.09Å; I224-S228 PolarHBondContact O-N 3.43Å; I224-S228 VanDerWaalsContact O-N 3.12Å; G226-S228 PolarHBondContact O-N 3.41Å; S228-W230 VanDerWaalsContact C-N 3.34Å; S228-V231 PolarHBondContact O-N 2.94Å; S228-Y232 VanDerWaalsContact O-CD2 3.29Å; S228-Y232 WeakPolarHBondContact O-CD2 3.12Å; S228-Y232 PolarHBondContact O-N 3.49Å
229H95.4Very high93.7Very high11 Ų1129.5 Ų29.55%0.05114%0.142CC..Hα-helixtrans-62.2-42.4174.1-177.455.2000111.4R173 D208 A210 D212 G226 Q227 V231 D233 V234R173-H229 PolarHBondContact NH2-NE2 3.33Å; D208-H229 IonicContact OD1-CE1 2.82Å; D208-H229 PolarHBondContact OD1-CE1 3.19Å; D208-H229 IonicContact OD2-CE1 3.77Å; A210-H229 HydrophobicContact CB-CB 4.37Å; A210-H229 PolarHBondContact O-ND1 2.98Å; A210-H229 VanDerWaalsContact O-ND1 3.13Å; D212-H229 HydrophobicContact CB-CB 4.43Å; D212-H229 IonicContact OD1-CD2 2.68Å; D212-H229 PolarHBondContact OD1-CD2 3.06Å; D212-H229 VanDerWaalsContact OD1-CD2 3.29Å; D212-H229 IonicContact OD1-CG 3.11Å; G226-H229 WeakPolarHBondContact O-CB 3.26Å; G226-H229 PolarHBondContact O-N 3.45Å; Q227-H229 VanDerWaalsContact C-N 3.3Å; Q227-H229 PolarHBondContact O-N 3.03Å; H229-V231 PolarHBondContact O-N 3.38Å; H229-D233 WeakPolarHBondContact ND1-CB 3.23Å; H229-D233 IonicContact ND1-OD2 3.26Å; H229-D233 PolarHBondContact ND1-OD2 3.23Å; H229-D233 WeakPolarHBondContact O-CA 3.34Å; H229-D233 WeakPolarHBondContact O-CB 3.37Å; H229-D233 PolarHBondContact O-N 2.75Å; H229-V234 PolarHBondContact O-N 3.1Å; H229-V234 VanDerWaalsContact O-N 3.1Å
230W94.8Very high94.1Very high39 Ų3921 Ų2115%0.14811%0.105CC..Iπ-helixtrans-60.4-46.1174.2-93.191.2000113.2L67 D91 G226 Q227 S228 V234 L235L67-W230 HydrophobicContact CD1-CB 3.81Å; L67-W230 HydrophobicContact CD1-CD2 3.84Å; L67-W230 HydrophobicContact CD1-CE3 3.62Å; L67-W230 HydrophobicContact CD1-CG 3.95Å; L67-W230 HydrophobicContact CD1-CZ3 4.46Å; L67-W230 HydrophobicContact CD2-CB 3.49Å; L67-W230 VanDerWaalsContact CD2-CB 3.49Å; L67-W230 HydrophobicContact CD2-CG 4.36Å; L67-W230 HydrophobicContact CG-CB 4.33Å; D91-W230 HydrophobicContact CB-CD2 4.08Å; D91-W230 HydrophobicContact CB-CG 4.06Å; D91-W230 HydrophobicContact CB-CZ2 4.41Å; D91-W230 WeakPolarHBondContact O-CH2 3.36Å; D91-W230 WeakPolarHBondContact O-CZ2 3.44Å; G226-W230 PolarHBondContact O-N 3.24Å; Q227-W230 WeakPolarHBondContact O-CB 3.4Å; Q227-W230 PolarHBondContact O-N 3.48Å; S228-W230 VanDerWaalsContact C-N 3.34Å; W230-V234 HydrophobicContact CD2-CB 3.93Å; W230-V234 HydrophobicContact CD2-CG1 3.97Å; W230-V234 HydrophobicContact CD2-CG2 4.18Å; W230-V234 HydrophobicContact CE3-CB 3.77Å; W230-V234 HydrophobicContact CE3-CG1 3.58Å; W230-V234 HydrophobicContact CG-CB 4.32Å; W230-V234 HydrophobicContact CG-CG2 4.26Å; W230-V234 HydrophobicContact CH2-CG1 3.82Å; W230-V234 HydrophobicContact CZ2-CG1 4.18Å; W230-V234 HydrophobicContact CZ3-CB 4.23Å; W230-V234 HydrophobicContact CZ3-CG1 3.5Å; W230-V234 PolarHBondContact O-N 3.09Å; W230-L235 HydrophobicContact CE3-CD2 4.45Å; W230-L235 HydrophobicContact CE3-CG 4.47Å; W230-L235 WeakPolarHBondContact O-CB 3.31Å; W230-L235 WeakPolarHBondContact O-CG 3.45Å; W230-L235 PolarHBondContact O-N 2.86Å
231V94.7Very high94.2Very high34 Ų3417.4 Ų17.421%0.2069%0.091CC..Iπ-helixtrans-62.7-47.5-179.1170.30000111.7Y20 E22 L67 Q227 S228 H229Y20-V231 HydrophobicContact CD1-CG2 3.87Å; Y20-V231 HydrophobicContact CE1-CG2 3.81Å; E22-V231 HydrophobicContact CG-CG2 4.45Å; L67-V231 HydrophobicContact CD2-CG2 3.89Å; Q227-V231 WeakPolarHBondContact O-CG2 3.39Å; Q227-V231 PolarHBondContact O-N 3.22Å; S228-V231 PolarHBondContact O-N 2.94Å; H229-V231 PolarHBondContact O-N 3.38Å
232Y94.4Very high94.1Very high15 Ų1521 Ų216%0.05911%0.109CC..Iπ-helixtrans-95-26.1-169.4-67.9-63.4000115.3E22 W31 W117 R209 A210 P222 S228 S236 R254E22-Y232 WeakPolarHBondContact OE2-CE2 3.36Å; E22-Y232 PolarHBondContact OE2-OH 2.75Å; E22-Y232 VanDerWaalsContact OE2-OH 3.06Å; W31-Y232 AromaticContact CZ2-CE2 3.83Å; W31-Y232 HydrophobicContact CZ2-CE2 3.83Å; W31-Y232 AromaticContact CZ2-CZ 3.59Å; W31-Y232 WeakPolarHBondContact CZ2-OH 3.31Å; W31-Y232 PolarHBondContact NE1-OH 3.15Å; W117-Y232 PolarHBondContact NE1-O 2.88Å; R209-Y232 HydrophobicContact CG-CG 4.44Å; A210-Y232 HydrophobicContact CB-CD2 4.39Å; P222-Y232 HydrophobicContact CB-CD2 4.1Å; P222-Y232 HydrophobicContact CB-CE2 4.03Å; S228-Y232 VanDerWaalsContact O-CD2 3.29Å; S228-Y232 WeakPolarHBondContact O-CD2 3.12Å; S228-Y232 PolarHBondContact O-N 3.49Å; Y232-S236 PolarHBondContact O-OG 3.16Å; Y232-R254 PolarHBondContact O-NH2 2.98Å
233D94.9Very high93.9Very high2 Ų224.1 Ų24.11%0.01112%0.12CC..Iπ-helixtrans-121.4-42.3-168.6-54-58000112R209 A210 H229 S236 F237 Y250 R254R209-D233 PolarHBondContact N-OD1 3.49Å; R209-D233 PolarHBondContact N-OD2 2.91Å; R209-D233 VanDerWaalsContact N-OD2 3.12Å; A210-D233 PolarHBondContact N-OD2 3.43Å; H229-D233 WeakPolarHBondContact ND1-CB 3.23Å; H229-D233 IonicContact ND1-OD2 3.26Å; H229-D233 PolarHBondContact ND1-OD2 3.23Å; H229-D233 WeakPolarHBondContact O-CA 3.34Å; H229-D233 WeakPolarHBondContact O-CB 3.37Å; H229-D233 PolarHBondContact O-N 2.75Å; D233-S236 WeakPolarHBondContact CA-OG 3.3Å; D233-S236 PolarHBondContact O-OG 3.03Å; D233-S236 VanDerWaalsContact O-OG 3.13Å; D233-F237 WeakPolarHBondContact O-CB 3.4Å; D233-F237 PolarHBondContact O-N 3.41Å; D233-Y250 VanDerWaalsContact O-CE2 3.32Å; D233-Y250 WeakPolarHBondContact O-CE2 3.48Å; D233-Y250 PolarHBondContact O-OH 3Å; D233-R254 IonicContact OD1-CZ 3.08Å; D233-R254 VanDerWaalsContact OD1-CZ 3.27Å; D233-R254 IonicContact OD1-NE 3.73Å; D233-R254 PolarHBondContact OD1-NE 3.01Å; D233-R254 IonicContact OD1-NH2 3.31Å; D233-R254 PolarHBondContact OD1-NH2 3.31Å
234V93.8Very high93.9Very high21 Ų2123 Ų2313%0.12712%0.118CC..Iπ-helixtrans-80.6-50.2-179.1-171.60000112.5H229 W230 S236 F237 Y238H229-V234 PolarHBondContact O-N 3.1Å; H229-V234 VanDerWaalsContact O-N 3.1Å; W230-V234 HydrophobicContact CD2-CB 3.93Å; W230-V234 HydrophobicContact CD2-CG1 3.97Å; W230-V234 HydrophobicContact CD2-CG2 4.18Å; W230-V234 HydrophobicContact CE3-CB 3.77Å; W230-V234 HydrophobicContact CE3-CG1 3.58Å; W230-V234 HydrophobicContact CG-CB 4.32Å; W230-V234 HydrophobicContact CG-CG2 4.26Å; W230-V234 HydrophobicContact CH2-CG1 3.82Å; W230-V234 HydrophobicContact CZ2-CG1 4.18Å; W230-V234 HydrophobicContact CZ3-CB 4.23Å; W230-V234 HydrophobicContact CZ3-CG1 3.5Å; W230-V234 PolarHBondContact O-N 3.09Å; V234-S236 VanDerWaalsContact C-N 3.33Å; V234-S236 PolarHBondContact O-N 3.48Å; V234-F237 WeakPolarHBondContact O-CB 3.49Å; V234-F237 PolarHBondContact O-N 3.05Å; V234-Y238 HydrophobicContact CG1-CD1 4.17Å; V234-Y238 HydrophobicContact CG1-CE1 3.74Å; V234-Y238 WeakPolarHBondContact O-CD1 3.45Å; V234-Y238 PolarHBondContact O-N 2.94Å
235L93.5Very high93.8Very high9 Ų928.9 Ų28.95%0.04715%0.15CC..Hα-helixtrans-63.9-39.9179.4-77.5-176.4000111.9E66 L67 A93 W230 F237 Y238 Y239E66-L235 HydrophobicContact CB-CD1 4.33Å; L67-L235 HydrophobicContact CB-CD1 4.06Å; A93-L235 HydrophobicContact CB-CD2 3.54Å; W230-L235 HydrophobicContact CE3-CD2 4.45Å; W230-L235 HydrophobicContact CE3-CG 4.47Å; W230-L235 WeakPolarHBondContact O-CB 3.31Å; W230-L235 WeakPolarHBondContact O-CG 3.45Å; W230-L235 PolarHBondContact O-N 2.86Å; L235-F237 VanDerWaalsContact C-N 3.32Å; L235-F237 PolarHBondContact O-N 3.19Å; L235-Y238 WeakPolarHBondContact O-CB 3.43Å; L235-Y238 PolarHBondContact O-N 3.24Å; L235-Y238 VanDerWaalsContact O-N 3.09Å; L235-Y239 HydrophobicContact CB-CE2 3.95Å; L235-Y239 WeakPolarHBondContact O-CD2 3.2Å; L235-Y239 PolarHBondContact O-N 2.49Å
236S94.6Very high93.9Very high1 Ų129.2 Ų29.21%0.00715%0.149CC..Hα-helixtrans-63.7-37.9175.454.80000111.7Y232 D233 V234 Y238 Y239 C240 Y250Y232-S236 PolarHBondContact O-OG 3.16Å; D233-S236 WeakPolarHBondContact CA-OG 3.3Å; D233-S236 PolarHBondContact O-OG 3.03Å; D233-S236 VanDerWaalsContact O-OG 3.13Å; V234-S236 VanDerWaalsContact C-N 3.33Å; V234-S236 PolarHBondContact O-N 3.48Å; S236-Y238 VanDerWaalsContact C-N 3.34Å; S236-Y239 PolarHBondContact O-N 3.21Å; S236-C240 VanDerWaalsContact O-CB 3.27Å; S236-C240 WeakPolarHBondContact O-CB 3.31Å; S236-C240 PolarHBondContact O-N 2.91Å; S236-C240 PolarHBondContact O-SG 3.41Å; S236-Y250 WeakPolarHBondContact OG-CE2 3.01Å
237F94.1Very high94Very high18 Ų1829.1 Ų29.18%0.07915%0.146CC..Hα-helixtrans-62.5-40.4169.9-172.5-95.1000111.8Y164 D233 V234 L235 C241 L242 Y250Y164-F237 HydrophobicContact CD1-CD1 4.29Å; Y164-F237 AromaticContact CD1-CE1 3.99Å; Y164-F237 HydrophobicContact CD1-CE1 3.99Å; D233-F237 WeakPolarHBondContact O-CB 3.4Å; D233-F237 PolarHBondContact O-N 3.41Å; V234-F237 WeakPolarHBondContact O-CB 3.49Å; V234-F237 PolarHBondContact O-N 3.05Å; L235-F237 VanDerWaalsContact C-N 3.32Å; L235-F237 PolarHBondContact O-N 3.19Å; F237-C241 HydrophobicContact CD1-CB 4.2Å; F237-C241 HydrophobicContact CD2-CB 3.87Å; F237-C241 HydrophobicContact CE1-CB 4.05Å; F237-C241 HydrophobicContact CE2-CB 3.72Å; F237-C241 WeakPolarHBondContact CE2-SG 3.03Å; F237-C241 HydrophobicContact CG-CB 4.12Å; F237-C241 HydrophobicContact CZ-CB 3.81Å; F237-C241 WeakPolarHBondContact O-CA 3.45Å; F237-C241 WeakPolarHBondContact O-CB 3.34Å; F237-C241 PolarHBondContact O-N 3.3Å; F237-L242 HydrophobicContact CD1-CD1 4.08Å; F237-L242 HydrophobicContact CD1-CD2 4.49Å; F237-L242 HydrophobicContact CD1-CG 3.93Å; F237-L242 HydrophobicContact CE1-CD1 4.03Å; F237-L242 HydrophobicContact CE1-CD2 3.77Å; F237-L242 HydrophobicContact CE1-CG 3.71Å; F237-L242 PolarHBondContact O-N 2.73Å; F237-Y250 HydrophobicContact CB-CD2 4.3Å; F237-Y250 HydrophobicContact CB-CE2 3.95Å; F237-Y250 HydrophobicContact CD2-CD1 4.02Å; F237-Y250 AromaticContact CD2-CE1 3.91Å; F237-Y250 HydrophobicContact CD2-CE1 3.91Å; F237-Y250 HydrophobicContact CD2-CG 4.41Å
238Y92.5Very high93.9Very high28 Ų2835.1 Ų35.111%0.1117%0.168CC..Iπ-helixtrans-62.1-48.6176.4-79.231.2000111.3A93 Y164 V234 L235 S236 L242 W243A93-Y238 HydrophobicContact CB-CD2 3.86Å; A93-Y238 HydrophobicContact CB-CE2 3.95Å; Y164-Y238 HydrophobicContact CD1-CE1 4.42Å; Y164-Y238 AromaticContact CE1-CE1 3.66Å; Y164-Y238 HydrophobicContact CE1-CE1 3.66Å; Y164-Y238 PolarHBondContact OH-OH 3.25Å; V234-Y238 HydrophobicContact CG1-CD1 4.17Å; V234-Y238 HydrophobicContact CG1-CE1 3.74Å; V234-Y238 WeakPolarHBondContact O-CD1 3.45Å; V234-Y238 PolarHBondContact O-N 2.94Å; L235-Y238 WeakPolarHBondContact O-CB 3.43Å; L235-Y238 PolarHBondContact O-N 3.24Å; L235-Y238 VanDerWaalsContact O-N 3.09Å; S236-Y238 VanDerWaalsContact C-N 3.34Å; Y238-L242 HydrophobicContact CD1-CD1 3.73Å; Y238-L242 HydrophobicContact CE1-CD1 3.92Å; Y238-L242 HydrophobicContact CG-CD1 4.28Å; Y238-L242 PolarHBondContact O-N 3.44Å; Y238-W243 AromaticContact CD2-CE2 3.91Å; Y238-W243 AromaticContact CD2-CH2 3.56Å; Y238-W243 HydrophobicContact CD2-CH2 3.56Å; Y238-W243 AromaticContact CD2-CZ2 3.3Å; Y238-W243 HydrophobicContact CD2-CZ2 3.3Å; Y238-W243 HydrophobicContact CD2-CZ3 4.35Å; Y238-W243 HydrophobicContact CE2-CH2 4.46Å; Y238-W243 HydrophobicContact CE2-CZ2 4.01Å; Y238-W243 HydrophobicContact CG-CH2 4.36Å; Y238-W243 HydrophobicContact CG-CZ2 4.14Å; Y238-W243 WeakPolarHBondContact O-CB 3.22Å; Y238-W243 PolarHBondContact O-N 3.07Å
239Y93.5Very high93.9Very high15 Ų1537.9 Ų37.96%0.05918%0.179CC..Iπ-helixtrans-62.7-52.4179.7-57.4-31.5000111.9E66 W109 K113 L235 S236 W243 S244E66-Y239 WeakPolarHBondContact CB-OH 3.34Å; E66-Y239 PolarHBondContact OE2-OH 3.42Å; W109-Y239 HydrophobicContact CH2-CD1 4.14Å; W109-Y239 AromaticContact CH2-CE1 3.53Å; W109-Y239 HydrophobicContact CH2-CE1 3.53Å; W109-Y239 AromaticContact CZ3-CD1 3.92Å; W109-Y239 HydrophobicContact CZ3-CD1 3.92Å; W109-Y239 AromaticContact CZ3-CE1 3.75Å; W109-Y239 HydrophobicContact CZ3-CE1 3.75Å; K113-Y239 HydrophobicContact CB-CD1 4Å; K113-Y239 HydrophobicContact CB-CD2 3.7Å; K113-Y239 HydrophobicContact CB-CE1 4.39Å; K113-Y239 HydrophobicContact CB-CE2 4.11Å; K113-Y239 HydrophobicContact CB-CG 3.65Å; K113-Y239 HydrophobicContact CG-CD1 4.48Å; K113-Y239 HydrophobicContact CG-CE1 4.49Å; L235-Y239 HydrophobicContact CB-CE2 3.95Å; L235-Y239 WeakPolarHBondContact O-CD2 3.2Å; L235-Y239 PolarHBondContact O-N 2.49Å; S236-Y239 PolarHBondContact O-N 3.21Å; Y239-W243 AromaticContact CD1-CE3 3.86Å; Y239-W243 HydrophobicContact CD1-CE3 3.86Å; Y239-W243 AromaticContact CD1-CZ3 3.88Å; Y239-W243 HydrophobicContact CD1-CZ3 3.88Å; Y239-W243 HydrophobicContact CE1-CE3 4.21Å; Y239-W243 AromaticContact CE1-CZ3 3.75Å; Y239-W243 HydrophobicContact CE1-CZ3 3.75Å; Y239-S244 VanDerWaalsContact O-CB 3.24Å; Y239-S244 WeakPolarHBondContact O-CB 3.11Å; Y239-S244 PolarHBondContact O-N 2.89Å; Y239-S244 PolarHBondContact O-OG 2.92Å
240C95.8Very high94Very high0 Ų037.7 Ų37.70%018%0.178CC..Iπ-helixtrans-79.9-44.1-172.9-650000112.8C114 S236 S244 N246 C247C114-C240 VanDerWaalsContact CA-SG 3.55Å; C114-C240 HydrophobicContact CB-CB 4Å; C114-C240 WeakPolarHBondContact CB-SG 3.01Å; C114-C240 WeakPolarHBondContact SG-CA 3.43Å; C114-C240 WeakPolarHBondContact SG-CB 3.18Å; C114-C240 CovalentContact SG-SG 2.04Å; C114-C240 PolarHBondContact SG-SG 3.28Å; S236-C240 VanDerWaalsContact O-CB 3.27Å; S236-C240 WeakPolarHBondContact O-CB 3.31Å; S236-C240 PolarHBondContact O-N 2.91Å; S236-C240 PolarHBondContact O-SG 3.41Å; C240-S244 PolarHBondContact O-OG 2.81Å; C240-S244 VanDerWaalsContact O-OG 3.08Å; C240-N246 CarbonylContact O-C 3.56Å; C240-N246 VanDerWaalsContact O-CA 3.26Å; C240-N246 WeakPolarHBondContact O-CA 3.26Å; C240-N246 PolarHBondContact O-N 2.79Å; C240-C247 PolarHBondContact O-N 3.38Å; C240-C247 VanDerWaalsContact O-N 3.13Å
241C93.7Very high94Very high8 Ų837.1 Ų37.15%0.05418%0.176CC..Iπ-helixtrans-94.3-54.6-172.8-81.50000113.5F237 D245 C247F237-C241 HydrophobicContact CD1-CB 4.2Å; F237-C241 HydrophobicContact CD2-CB 3.87Å; F237-C241 HydrophobicContact CE1-CB 4.05Å; F237-C241 HydrophobicContact CE2-CB 3.72Å; F237-C241 WeakPolarHBondContact CE2-SG 3.03Å; F237-C241 HydrophobicContact CG-CB 4.12Å; F237-C241 HydrophobicContact CZ-CB 3.81Å; F237-C241 WeakPolarHBondContact O-CA 3.45Å; F237-C241 WeakPolarHBondContact O-CB 3.34Å; F237-C241 PolarHBondContact O-N 3.3Å; C241-D245 PolarHBondContact O-N 2.86Å; C241-C247 WeakPolarHBondContact CA-SG 2.94Å; C241-C247 HydrophobicContact CB-CB 4.23Å; C241-C247 WeakPolarHBondContact CB-SG 3.23Å; C241-C247 WeakPolarHBondContact SG-CA 3.45Å; C241-C247 WeakPolarHBondContact SG-CB 3.36Å; C241-C247 CovalentContact SG-SG 2.03Å; C241-C247 PolarHBondContact SG-SG 2.87Å
242L90.8Very high94Very high84 Ų8439.6 Ų39.644%0.4418%0.184SC..Iπ-helixtrans-82.2-39.1-167.1-61.7-177.6000113.3Y164 F237 Y238Y164-L242 HydrophobicContact CD1-CD1 4.15Å; Y164-L242 HydrophobicContact CE1-CD1 3.99Å; F237-L242 HydrophobicContact CD1-CD1 4.08Å; F237-L242 HydrophobicContact CD1-CD2 4.49Å; F237-L242 HydrophobicContact CD1-CG 3.93Å; F237-L242 HydrophobicContact CE1-CD1 4.03Å; F237-L242 HydrophobicContact CE1-CD2 3.77Å; F237-L242 HydrophobicContact CE1-CG 3.71Å; F237-L242 PolarHBondContact O-N 2.73Å; Y238-L242 HydrophobicContact CD1-CD1 3.73Å; Y238-L242 HydrophobicContact CE1-CD1 3.92Å; Y238-L242 HydrophobicContact CG-CD1 4.28Å; Y238-L242 PolarHBondContact O-N 3.44Å
243W91Very high94.1Very high66 Ų6640 Ų4025%0.2519%0.186CC..Iπ-helixtrans-102.2-25.9-170.1-61.1-18.3000114.1A93 A95 F102 A107 W109 A110 Y238 Y239A93-W243 HydrophobicContact CB-CH2 3.76Å; A93-W243 HydrophobicContact CB-CZ2 4.42Å; A95-W243 HydrophobicContact CB-CH2 3.6Å; A95-W243 HydrophobicContact CB-CZ2 4.27Å; A95-W243 HydrophobicContact CB-CZ3 4.09Å; F102-W243 HydrophobicContact CE2-CD2 4.34Å; F102-W243 HydrophobicContact CE2-CE3 4.19Å; A107-W243 WeakPolarHBondContact CA-O 3.3Å; W109-W243 HydrophobicContact CH2-CZ3 4.46Å; W109-W243 AromaticContact CZ3-CE3 3.95Å; W109-W243 HydrophobicContact CZ3-CE3 3.95Å; W109-W243 AromaticContact CZ3-CZ3 3.91Å; W109-W243 HydrophobicContact CZ3-CZ3 3.91Å; A110-W243 HydrophobicContact CB-CB 3.52Å; Y238-W243 AromaticContact CD2-CE2 3.91Å; Y238-W243 AromaticContact CD2-CH2 3.56Å; Y238-W243 HydrophobicContact CD2-CH2 3.56Å; Y238-W243 AromaticContact CD2-CZ2 3.3Å; Y238-W243 HydrophobicContact CD2-CZ2 3.3Å; Y238-W243 HydrophobicContact CD2-CZ3 4.35Å; Y238-W243 HydrophobicContact CE2-CH2 4.46Å; Y238-W243 HydrophobicContact CE2-CZ2 4.01Å; Y238-W243 HydrophobicContact CG-CH2 4.36Å; Y238-W243 HydrophobicContact CG-CZ2 4.14Å; Y238-W243 WeakPolarHBondContact O-CB 3.22Å; Y238-W243 PolarHBondContact O-N 3.07Å; Y239-W243 AromaticContact CD1-CE3 3.86Å; Y239-W243 HydrophobicContact CD1-CE3 3.86Å; Y239-W243 AromaticContact CD1-CZ3 3.88Å; Y239-W243 HydrophobicContact CD1-CZ3 3.88Å; Y239-W243 HydrophobicContact CE1-CE3 4.21Å; Y239-W243 AromaticContact CE1-CZ3 3.75Å; Y239-W243 HydrophobicContact CE1-CZ3 3.75Å
244S93.7Very high94.1Very high12 Ų1239.9 Ų39.98%0.08419%0.186CC..THydrogen-bonded Turntrans-109.5-12.9176.770.10000115Y239 C240 N246Y239-S244 VanDerWaalsContact O-CB 3.24Å; Y239-S244 WeakPolarHBondContact O-CB 3.11Å; Y239-S244 PolarHBondContact O-N 2.89Å; Y239-S244 PolarHBondContact O-OG 2.92Å; C240-S244 PolarHBondContact O-OG 2.81Å; C240-S244 VanDerWaalsContact O-OG 3.08Å; S244-N246 VanDerWaalsContact C-N 3.27Å; S244-N246 PolarHBondContact O-N 3.32Å; S244-N246 PolarHBondContact O-ND2 2.64Å
245D93.2Very high94.1Very high142 Ų14241.2 Ų41.276%0.75920%0.195SC*.SBendtrans58.833.8-175.5-161.227.9000114.1C241C241-D245 PolarHBondContact O-N 2.86Å
246N95.4Very high94.1Very high58 Ų5841.9 Ų41.931%0.3120%0.201SC..  trans-118.243.8178.9-74.6-91.4000112.2L111 C240 S244 Y248 Y249L111-N246 HydrophobicContact CD1-CB 4.19Å; C240-N246 CarbonylContact O-C 3.56Å; C240-N246 VanDerWaalsContact O-CA 3.26Å; C240-N246 WeakPolarHBondContact O-CA 3.26Å; C240-N246 PolarHBondContact O-N 2.79Å; S244-N246 VanDerWaalsContact C-N 3.27Å; S244-N246 PolarHBondContact O-N 3.32Å; S244-N246 PolarHBondContact O-ND2 2.64Å; N246-Y248 PolarHBondContact O-N 3.08Å; N246-Y249 HydrophobicContact CB-CD2 3.95Å; N246-Y249 HydrophobicContact CB-CE2 4.18Å; N246-Y249 PolarHBondContact O-N 3.27Å
247C93.4Very high93.7Very high14 Ų1443 Ų4310%0.09521%0.208CC..Hα-helixtrans-50.6-26.8-177.2-85.80000115.7I202 C240 C241 Y249 Y250 F251I202-C247 HydrophobicContact CG2-CB 4.3Å; C240-C247 PolarHBondContact O-N 3.38Å; C240-C247 VanDerWaalsContact O-N 3.13Å; C241-C247 WeakPolarHBondContact CA-SG 2.94Å; C241-C247 HydrophobicContact CB-CB 4.23Å; C241-C247 WeakPolarHBondContact CB-SG 3.23Å; C241-C247 WeakPolarHBondContact SG-CA 3.45Å; C241-C247 WeakPolarHBondContact SG-CB 3.36Å; C241-C247 CovalentContact SG-SG 2.03Å; C241-C247 PolarHBondContact SG-SG 2.87Å; C247-Y249 PolarHBondContact O-N 2.65Å; C247-Y250 WeakPolarHBondContact O-CA 3.46Å; C247-Y250 WeakPolarHBondContact O-CB 3.34Å; C247-Y250 PolarHBondContact O-N 2.69Å; C247-F251 HydrophobicContact CB-CD2 4.11Å; C247-F251 HydrophobicContact CB-CE2 3.66Å; C247-F251 HydrophobicContact CB-CZ 4.24Å; C247-F251 PolarHBondContact O-N 3.2Å
248Y93.2Very high92.9Very high160 Ų16044.2 Ų44.263%0.62722%0.215SC*.Hα-helixtrans-52.9-38.6179.8150.7-97.5000112.8N246 Y250 F251 K252N246-Y248 PolarHBondContact O-N 3.08Å; Y248-Y250 VanDerWaalsContact C-N 3.31Å; Y248-Y250 PolarHBondContact O-N 3.01Å; Y248-F251 PolarHBondContact O-N 3.18Å; Y248-K252 WeakPolarHBondContact O-CB 3.03Å; Y248-K252 PolarHBondContact O-N 2.89Å
249Y95.9Very high93Very high59 Ų5943.2 Ų43.223%0.23121%0.212CC..Hα-helixtrans-63.8-39.1176.7-68.8-73.1000111.7L111 C114 L115 W117 D118 N246 C247 K252 H253L111-Y249 HydrophobicContact CD1-CE2 4.42Å; C114-Y249 VanDerWaalsContact SG-CB 3.56Å; L115-Y249 HydrophobicContact CD2-CD1 4.39Å; L115-Y249 HydrophobicContact CD2-CD2 4.5Å; L115-Y249 HydrophobicContact CD2-CE1 3.77Å; L115-Y249 HydrophobicContact CD2-CE2 3.91Å; W117-Y249 WeakPolarHBondContact CZ3-O 3.34Å; D118-Y249 HydrophobicContact CB-CD1 4.13Å; N246-Y249 HydrophobicContact CB-CD2 3.95Å; N246-Y249 HydrophobicContact CB-CE2 4.18Å; N246-Y249 PolarHBondContact O-N 3.27Å; C247-Y249 PolarHBondContact O-N 2.65Å; Y249-K252 WeakPolarHBondContact O-CB 3.3Å; Y249-H253 PolarHBondContact O-CD2 3.33Å
250Y96.3Very high93Very high7 Ų749.1 Ų49.13%0.02724%0.235CC..Hα-helixtrans-63.9-51.5176.6-174.6-93.7000111.1W117 T206 D233 S236 F237 C247 Y248 K252 H253 R254W117-Y250 AromaticContact CH2-CD2 3.8Å; W117-Y250 HydrophobicContact CH2-CD2 3.8Å; W117-Y250 HydrophobicContact CH2-CG 4.34Å; W117-Y250 HydrophobicContact CZ2-CD2 4.14Å; W117-Y250 HydrophobicContact CZ2-CE2 4.48Å; W117-Y250 HydrophobicContact CZ3-CD2 4.39Å; T206-Y250 HydrophobicContact CG2-CE1 3.95Å; D233-Y250 VanDerWaalsContact O-CE2 3.32Å; D233-Y250 WeakPolarHBondContact O-CE2 3.48Å; D233-Y250 PolarHBondContact O-OH 3Å; S236-Y250 WeakPolarHBondContact OG-CE2 3.01Å; F237-Y250 HydrophobicContact CB-CD2 4.3Å; F237-Y250 HydrophobicContact CB-CE2 3.95Å; F237-Y250 HydrophobicContact CD2-CD1 4.02Å; F237-Y250 AromaticContact CD2-CE1 3.91Å; F237-Y250 HydrophobicContact CD2-CE1 3.91Å; F237-Y250 HydrophobicContact CD2-CG 4.41Å; C247-Y250 WeakPolarHBondContact O-CA 3.46Å; C247-Y250 WeakPolarHBondContact O-CB 3.34Å; C247-Y250 PolarHBondContact O-N 2.69Å; Y248-Y250 VanDerWaalsContact C-N 3.31Å; Y248-Y250 PolarHBondContact O-N 3.01Å; Y250-K252 VanDerWaalsContact C-N 3.28Å; Y250-K252 PolarHBondContact O-N 3.48Å; Y250-H253 PolarHBondContact O-N 2.97Å; Y250-R254 HydrophobicContact CD1-CB 3.97Å; Y250-R254 HydrophobicContact CD1-CG 4.17Å; Y250-R254 HydrophobicContact CD2-CG 4.32Å; Y250-R254 HydrophobicContact CE1-CB 3.61Å; Y250-R254 HydrophobicContact CE1-CG 3.75Å; Y250-R254 HydrophobicContact CE2-CG 3.91Å; Y250-R254 HydrophobicContact CG-CG 4.44Å; Y250-R254 WeakPolarHBondContact O-CB 3.41Å; Y250-R254 PolarHBondContact O-N 3.23Å
251F95.1Very high92.8Very high26 Ų2658.3 Ų58.311%0.11427%0.269CS..Hα-helixtrans-69.9-21.4-177.4-59.3-37000114.7T198 I202 T206 C247 Y248 H253 R254 P255T198-F251 VanDerWaalsContact CB-CD1 3.44Å; T198-F251 HydrophobicContact CG2-CD1 3.35Å; T198-F251 HydrophobicContact CG2-CE1 3.51Å; T198-F251 HydrophobicContact CG2-CG 4.06Å; T198-F251 HydrophobicContact CG2-CZ 4.29Å; I202-F251 HydrophobicContact CB-CE2 4.32Å; I202-F251 HydrophobicContact CB-CZ 4.19Å; I202-F251 HydrophobicContact CG2-CE2 4.19Å; I202-F251 WeakPolarHBondContact O-CZ 3.25Å; T206-F251 HydrophobicContact CG2-CE1 4.48Å; C247-F251 HydrophobicContact CB-CD2 4.11Å; C247-F251 HydrophobicContact CB-CE2 3.66Å; C247-F251 HydrophobicContact CB-CZ 4.24Å; C247-F251 PolarHBondContact O-N 3.2Å; Y248-F251 PolarHBondContact O-N 3.18Å; F251-H253 PolarHBondContact O-N 2.85Å; F251-R254 CarbonylContact O-C 3.54Å; F251-R254 PolarHBondContact O-N 2.8Å; F251-P255 WeakPolarHBondContact O-CA 3.36Å
252K94.7Very high93Very high87 Ų8759 Ų5938%0.37827%0.271SS..Hα-helixtrans-56.1-40.5168.3176.5-171162.6-1560111.5D118 N122 Y248 Y249 Y250D118-K252 IonicContact OD1-NZ 2.65Å; D118-K252 PolarHBondContact OD1-NZ 3Å; D118-K252 IonicContact OD2-NZ 3.8Å; N122-K252 PolarHBondContact OD1-NZ 3.36Å; Y248-K252 WeakPolarHBondContact O-CB 3.03Å; Y248-K252 PolarHBondContact O-N 2.89Å; Y249-K252 WeakPolarHBondContact O-CB 3.3Å; Y250-K252 VanDerWaalsContact C-N 3.28Å; Y250-K252 PolarHBondContact O-N 3.48Å
253H96.1Very high93.2Very high22 Ų2260 Ų6010%0.10227%0.273CS..Hα-helixtrans-100-12.7-179.2-61.2-64.6000114.1W117 D118 E121 N122 Y249 Y250 F251W117-H253 HydrophobicContact CH2-CB 3.87Å; W117-H253 AromaticContact CH2-CD2 3.76Å; W117-H253 HydrophobicContact CZ2-CB 4.33Å; W117-H253 AromaticContact CZ3-CD2 3.77Å; D118-H253 PolarHBondContact O-NE2 2.92Å; D118-H253 IonicContact OD1-CD2 2.65Å; D118-H253 PolarHBondContact OD1-CD2 3.29Å; D118-H253 IonicContact OD1-CE1 2.98Å; D118-H253 IonicContact OD1-NE2 2.87Å; D118-H253 PolarHBondContact OD1-NE2 2.93Å; E121-H253 HydrophobicContact CB-CB 4.39Å; E121-H253 VanDerWaalsContact CB-CE1 3.48Å; E121-H253 WeakPolarHBondContact CB-CE1 3.42Å; E121-H253 WeakPolarHBondContact CB-NE2 3.39Å; E121-H253 HydrophobicContact CG-CB 4.37Å; N122-H253 PolarHBondContact OD1-CE1 2.86Å; Y249-H253 PolarHBondContact O-CD2 3.33Å; Y250-H253 PolarHBondContact O-N 2.97Å; F251-H253 PolarHBondContact O-N 2.85Å
254R95.8Very high93.5Very high0 Ų057.7 Ų57.70%027%0.267CS..SBendtrans-124.953.2179.8-55.7-73.8179.8-70.5-7.6111.2E121 T206 P207 R209 Y232 D233 Y250 F251E121-R254 IonicContact OE1-CZ 3.94Å; E121-R254 IonicContact OE1-NH1 3.12Å; E121-R254 IonicContact OE1-NH2 3.8Å; E121-R254 PolarHBondContact OE1-NH2 2.64Å; E121-R254 IonicContact OE2-CZ 3.26Å; E121-R254 IonicContact OE2-NH1 3.86Å; E121-R254 PolarHBondContact OE2-NH1 3.4Å; E121-R254 IonicContact OE2-NH2 3.18Å; T206-R254 HydrophobicContact CG2-CB 4.44Å; P207-R254 WeakPolarHBondContact O-CD 3.48Å; R209-R254 VanDerWaalsContact CB-NH2 3.32Å; Y232-R254 PolarHBondContact O-NH2 2.98Å; D233-R254 IonicContact OD1-CZ 3.08Å; D233-R254 VanDerWaalsContact OD1-CZ 3.27Å; D233-R254 IonicContact OD1-NE 3.73Å; D233-R254 PolarHBondContact OD1-NE 3.01Å; D233-R254 IonicContact OD1-NH2 3.31Å; D233-R254 PolarHBondContact OD1-NH2 3.31Å; Y250-R254 HydrophobicContact CD1-CB 3.97Å; Y250-R254 HydrophobicContact CD1-CG 4.17Å; Y250-R254 HydrophobicContact CD2-CG 4.32Å; Y250-R254 HydrophobicContact CE1-CB 3.61Å; Y250-R254 HydrophobicContact CE1-CG 3.75Å; Y250-R254 HydrophobicContact CE2-CG 3.91Å; Y250-R254 HydrophobicContact CG-CG 4.44Å; Y250-R254 WeakPolarHBondContact O-CB 3.41Å; Y250-R254 PolarHBondContact O-N 3.23Å; F251-R254 CarbonylContact O-C 3.54Å; F251-R254 PolarHBondContact O-N 2.8Å
255P94.8Very high93.6Very high50 Ų5057.4 Ų57.433%0.32527%0.265SS..PPolyproline II helixtrans-72.3139-178.531.4-35.7000110.6L128 P207 F251L128-P255 HydrophobicContact CD1-CG 3.75Å; P207-P255 WeakPolarHBondContact CD-O 3.05Å; P207-P255 WeakPolarHBondContact CG-O 3.37Å; F251-P255 WeakPolarHBondContact O-CA 3.36Å
256S93.1Very high93.9Very high23 Ų2352 Ų5216%0.16124%0.239CC..PPolyproline II helixtrans-59.1141173.1-57.40000111.7L197 T198 S205 D258L197-S256 WeakPolarHBondContact CA-OG 3.4Å; T198-S256 WeakPolarHBondContact CG2-OG 3.37Å; T198-S256 PolarHBondContact N-OG 3.12Å; T198-S256 PolarHBondContact OG1-N 2.87Å; T198-S256 VanDerWaalsContact OG1-N 3.09Å; T198-S256 PolarHBondContact OG1-OG 2.04Å; S205-S256 VanDerWaalsContact O-CA 3.3Å; S205-S256 WeakPolarHBondContact O-CA 3.36Å; S205-S256 VanDerWaalsContact O-CB 3.3Å; S205-S256 WeakPolarHBondContact O-CB 3.34Å; S205-S256 PolarHBondContact O-OG 2.85Å; S256-D258 PolarHBondContact O-N 2.8Å
257S85.4Confident94Very high23 Ų2349.7 Ų49.716%0.16123%0.227CC..PPolyproline II helixtrans-66.7123.8162.5-179.90000109.1N133 Q195N133-S257 PolarHBondContact OD1-OG 2.96Å; Q195-S257 PolarHBondContact NE2-O 2.86Å; Q195-S257 PolarHBondContact OE1-O 3.28Å
258D78.2Confident94.3Very high44 Ų4449 Ų4924%0.23522%0.223CC..PPolyproline II helixtrans-71.2136.916269.962.7000109.2S256 R260S256-D258 PolarHBondContact O-N 2.8Å; D258-R260 PolarHBondContact O-N 2.85Å; D258-R260 VanDerWaalsContact OD1-CB 3.31Å; D258-R260 WeakPolarHBondContact OD1-CB 3.35Å; D258-R260 WeakPolarHBondContact OD1-CG 3.47Å; D258-R260 IonicContact OD1-CZ 2.88Å; D258-R260 PolarHBondContact OD1-N 3.13Å; D258-R260 IonicContact OD1-NE 2.91Å; D258-R260 PolarHBondContact OD1-NE 3.26Å; D258-R260 IonicContact OD1-NH2 4Å; D258-R260 IonicContact OD2-CZ 3.23Å; D258-R260 VanDerWaalsContact OD2-CZ 3.31Å; D258-R260 IonicContact OD2-NE 2.71Å; D258-R260 PolarHBondContact OD2-NE 3.32Å; D258-R260 IonicContact OD2-NH2 3.71Å; D258-R260 PolarHBondContact OD2-NH2 2.93Å
259C93.6Very high94.5Very high7 Ų741.4 Ų41.45%0.04719%0.193CC..G310 helixtrans-74.17.9-171.177.50000114C134 C136 R261 Y262C134-C259 VanDerWaalsContact O-CB 3.25Å; C134-C259 WeakPolarHBondContact O-CB 3.48Å; C136-C259 WeakPolarHBondContact CA-SG 3.35Å; C136-C259 HydrophobicContact CB-CB 3.77Å; C136-C259 WeakPolarHBondContact CB-SG 3.47Å; C136-C259 WeakPolarHBondContact SG-CB 3.29Å; C136-C259 PolarHBondContact SG-O 3.11Å; C136-C259 VanDerWaalsContact SG-O 3.34Å; C136-C259 CovalentContact SG-SG 2.04Å; C136-C259 PolarHBondContact SG-SG 2.93Å; C259-R261 PolarHBondContact O-N 3.12Å; C259-R261 VanDerWaalsContact O-N 3.08Å; C259-Y262 WeakPolarHBondContact O-CB 3.29Å; C259-Y262 PolarHBondContact O-N 3.16Å
260R93.3Very high94.7Very high140 Ų14038.7 Ų38.753%0.52818%0.182SC..G310 helixtrans-62.2-22.9-172.5-67.5-177.7-73.7-172.70.4113.8D258D258-R260 PolarHBondContact O-N 2.85Å; D258-R260 VanDerWaalsContact OD1-CB 3.31Å; D258-R260 WeakPolarHBondContact OD1-CB 3.35Å; D258-R260 WeakPolarHBondContact OD1-CG 3.47Å; D258-R260 IonicContact OD1-CZ 2.88Å; D258-R260 PolarHBondContact OD1-N 3.13Å; D258-R260 IonicContact OD1-NE 2.91Å; D258-R260 PolarHBondContact OD1-NE 3.26Å; D258-R260 IonicContact OD1-NH2 4Å; D258-R260 IonicContact OD2-CZ 3.23Å; D258-R260 VanDerWaalsContact OD2-CZ 3.31Å; D258-R260 IonicContact OD2-NE 2.71Å; D258-R260 PolarHBondContact OD2-NE 3.32Å; D258-R260 IonicContact OD2-NH2 3.71Å; D258-R260 PolarHBondContact OD2-NH2 2.93Å
261R93.2Very high94.7Very high193 Ų19338.4 Ų38.473%0.72818%0.181SC*.G310 helixtrans-104.1-0.2179.5-64.9-177.4178.6-177.60.4113.1N133 C259N133-R261 WeakPolarHBondContact ND2-CB 3.31Å; N133-R261 PolarHBondContact ND2-O 2.88Å; C259-R261 PolarHBondContact O-N 3.12Å; C259-R261 VanDerWaalsContact O-N 3.08Å
262Y95.9Very high94.6Very high23 Ų2337.2 Ų37.29%0.0918%0.176CC..  trans-67.2135.9172.6175.4-102.1000110C134 P135 Q140 D144 F148 C259C134-Y262 VanDerWaalsContact O-CB 3.28Å; C134-Y262 WeakPolarHBondContact O-CB 3.37Å; P135-Y262 HydrophobicContact CB-CD1 4.36Å; P135-Y262 HydrophobicContact CB-CD2 4.39Å; P135-Y262 HydrophobicContact CB-CE1 3.96Å; P135-Y262 HydrophobicContact CB-CE2 4Å; P135-Y262 HydrophobicContact CG-CD2 4.21Å; P135-Y262 HydrophobicContact CG-CE1 4.49Å; P135-Y262 HydrophobicContact CG-CE2 3.65Å; Q140-Y262 HydrophobicContact CB-CE1 4.23Å; Q140-Y262 HydrophobicContact CG-CE1 4.46Å; D144-Y262 WeakPolarHBondContact OD2-CE2 3.44Å; D144-Y262 PolarHBondContact OD2-OH 3.34Å; F148-Y262 HydrophobicContact CE2-CE2 4.12Å; C259-Y262 WeakPolarHBondContact O-CB 3.29Å; C259-Y262 PolarHBondContact O-N 3.16Å
263Q96.1Very high94.2Very high104 Ų10433.2 Ų33.249%0.48616%0.159SC..  trans-126121174.8-65178.12.700107.2R147 E405R147-Q263 PolarHBondContact NH1-O 3.04Å; R147-Q263 PolarHBondContact NH2-O 3.01Å; Q263-E405 VanDerWaalsContact OE1-CB 3.24Å
264S96.2Very high94.1Very high17 Ų1732.1 Ų32.112%0.11915%0.154CC..PPolyproline II helixtrans-62.3145.4177.6-53.30000110.9L540S264-L540 WeakPolarHBondContact CB-O 3Å; S264-L540 PolarHBondContact OG-O 2.87Å
265P97.9Very high94.2Very high6 Ų632.1 Ų32.14%0.03915%0.154CC..PPolyproline II helixtrans-66.1156.1168.631.3-37.3000111.2D144 L402 L403 L540D144-P265 HydrophobicContact CB-CG 4.3Å; P265-L402 HydrophobicContact CB-CB 4.41Å; P265-L402 HydrophobicContact CB-CD2 4.47Å; P265-L402 HydrophobicContact CG-CD2 4.14Å; P265-L403 CarbonylContact C-O 3.39Å; P265-L403 VanDerWaalsContact CA-O 3.23Å; P265-L403 WeakPolarHBondContact CA-O 3.43Å; P265-L403 WeakPolarHBondContact CB-O 3.22Å; P265-L540 HydrophobicContact CG-CD1 4.2Å; P265-L540 HydrophobicContact CG-CD2 3.85Å
266S98.1Very high94.3Very high30 Ų3030 Ų3021%0.2114%0.139CC..EExtended strand (participates in β ladder)trans-86.3147.8163.4-53.70000109.8L402 L403S266-L402 WeakPolarHBondContact O-CA 3.28Å; S266-L403 PolarHBondContact N-O 3.04Å; S266-L403 PolarHBondContact O-N 3.49Å
267S98.3Very high94.6Very high9 Ų929.4 Ų29.46%0.06313%0.134CC..EExtended strand (participates in β ladder)trans-119.4144.3179.974.80000111.3V401 H533 V537S267-V401 CarbonylContact C-O 3.57Å; S267-V401 VanDerWaalsContact CA-O 3.31Å; S267-V401 WeakPolarHBondContact CA-O 3.17Å; S267-H533 PolarHBondContact OG-CE1 2.8Å; S267-H533 VanDerWaalsContact OG-CE1 3.31Å; S267-V537 VanDerWaalsContact OG-CG2 3.28Å; S267-V537 WeakPolarHBondContact OG-CG2 3.48Å
268A98.8Very high95.2Very high0 Ų028.4 Ų28.40%013%0.127CC..EExtended strand (participates in β ladder)trans-137.2152.7171.500000108.9I277 F279 T400 V401 L415A268-I277 CarbonylContact C-O 3.52Å; A268-I277 VanDerWaalsContact CA-O 3.3Å; A268-I277 WeakPolarHBondContact CA-O 3.41Å; A268-I277 WeakPolarHBondContact CB-O 2.86Å; A268-F279 HydrophobicContact CB-CD1 3.53Å; A268-F279 HydrophobicContact CB-CD2 4.04Å; A268-F279 HydrophobicContact CB-CE1 3.5Å; A268-F279 HydrophobicContact CB-CE2 4.01Å; A268-F279 HydrophobicContact CB-CG 3.79Å; A268-F279 HydrophobicContact CB-CZ 3.74Å; A268-T400 CarbonylContact O-C 3.45Å; A268-T400 WeakPolarHBondContact O-CA 3.24Å; A268-V401 PolarHBondContact N-O 3.37Å; A268-V401 PolarHBondContact O-N 3.48Å; A268-L415 HydrophobicContact CB-CB 3.94Å; A268-L415 HydrophobicContact CB-CD1 4.06Å; A268-L415 HydrophobicContact CB-CD2 3.97Å; A268-L415 HydrophobicContact CB-CG 4.19Å
269V98.8Very high96.2Very high0 Ų027.1 Ų27.10%012%0.119CC..EExtended strand (participates in β ladder)trans-141.1145.1-17265.50000113.1F271 F276 I277 T398 T399 H533V269-F271 HydrophobicContact CG1-CD1 3.82Å; V269-F271 HydrophobicContact CG1-CE1 4.03Å; V269-F271 HydrophobicContact CG2-CB 4.35Å; V269-F271 HydrophobicContact CG2-CD1 4.09Å; V269-F276 CarbonylContact O-C 3.56Å; V269-F276 WeakPolarHBondContact O-CA 3.04Å; V269-I277 HydrophobicContact CG1-CB 3.87Å; V269-I277 HydrophobicContact CG1-CD1 4.04Å; V269-I277 HydrophobicContact CG1-CG1 4.18Å; V269-I277 PolarHBondContact N-O 3.24Å; V269-I277 PolarHBondContact O-N 3.38Å; V269-T398 HydrophobicContact CG2-CG2 3.75Å; V269-T399 CarbonylContact C-O 3.58Å; V269-T399 WeakPolarHBondContact CA-O 3.4Å; V269-H533 HydrophobicContact CB-CB 4.43Å; V269-H533 HydrophobicContact CG1-CB 3.9Å; V269-H533 WeakPolarHBondContact CG1-ND1 3.42Å
270V98.5Very high96.4Very high2 Ų228.4 Ų28.41%0.01213%0.126CC..EExtended strand (participates in β ladder)trans-115.6128.4164.6-169.10000108.4P274 H275 F276 L294 L323 T398 T399 L415V270-P274 HydrophobicContact CG1-CB 3.57Å; V270-H275 CarbonylContact C-O 3.6Å; V270-H275 VanDerWaalsContact CA-O 3.3Å; V270-H275 WeakPolarHBondContact CA-O 3.12Å; V270-F276 HydrophobicContact CB-CD1 4.41Å; V270-F276 HydrophobicContact CB-CE1 4.26Å; V270-F276 HydrophobicContact CG1-CD1 4.23Å; V270-F276 HydrophobicContact CG1-CE1 3.8Å; V270-F276 HydrophobicContact CG1-CE2 4.27Å; V270-F276 HydrophobicContact CG1-CZ 3.81Å; V270-F276 HydrophobicContact CG2-CD1 3.61Å; V270-F276 HydrophobicContact CG2-CE1 3.48Å; V270-F276 VanDerWaalsContact CG2-CE1 3.48Å; V270-F276 HydrophobicContact CG2-CZ 4.33Å; V270-L294 HydrophobicContact CG2-CD1 4.16Å; V270-L294 HydrophobicContact CG2-CD2 4.1Å; V270-L323 HydrophobicContact CG1-CD2 4.47Å; V270-T398 CarbonylContact O-C 3.6Å; V270-T398 WeakPolarHBondContact O-CA 3.35Å; V270-T399 PolarHBondContact N-O 2.88Å; V270-T399 PolarHBondContact O-N 3.33Å; V270-L415 HydrophobicContact CG2-CD2 3.9Å
271F97.1Very high96.6Very high1 Ų124 Ų240%0.00412%0.124CC..EExtended strand (participates in β ladder)trans-154.4163.7-174.764.3-76.2000111.5V269 P274 H275 I277 T398 F509 T526 F530V269-F271 HydrophobicContact CG1-CD1 3.82Å; V269-F271 HydrophobicContact CG1-CE1 4.03Å; V269-F271 HydrophobicContact CG2-CB 4.35Å; V269-F271 HydrophobicContact CG2-CD1 4.09Å; F271-P274 CarbonylContact O-C 3.55Å; F271-P274 WeakPolarHBondContact O-CA 3.17Å; F271-H275 HydrophobicContact CD1-CB 4.27Å; F271-H275 HydrophobicContact CD2-CB 4.43Å; F271-H275 HydrophobicContact CE1-CB 3.8Å; F271-H275 HydrophobicContact CE2-CB 3.98Å; F271-H275 AromaticContact CE2-CD2 3.9Å; F271-H275 HydrophobicContact CZ-CB 3.63Å; F271-H275 PolarHBondContact N-O 3.47Å; F271-H275 PolarHBondContact O-N 3.07Å; F271-I277 HydrophobicContact CE1-CD1 3.94Å; F271-I277 HydrophobicContact CE1-CG1 4.01Å; F271-I277 HydrophobicContact CZ-CD1 4.27Å; F271-T398 HydrophobicContact CB-CG2 3.92Å; F271-F509 HydrophobicContact CE2-CB 4.27Å; F271-F509 HydrophobicContact CE2-CD2 4.13Å; F271-F509 HydrophobicContact CE2-CG 4.27Å; F271-F509 AromaticContact CZ-CD2 3.89Å; F271-F509 HydrophobicContact CZ-CD2 3.89Å; F271-F509 HydrophobicContact CZ-CE2 4.16Å; F271-F509 HydrophobicContact CZ-CG 4.27Å; F271-T526 HydrophobicContact CD2-CG2 3.82Å; F271-T526 HydrophobicContact CE2-CG2 3.89Å; F271-F530 HydrophobicContact CE2-CB 3.95Å; F271-F530 HydrophobicContact CE2-CD2 4.24Å; F271-F530 HydrophobicContact CZ-CB 4.41Å; F271-F530 AromaticContact CZ-CD2 3.91Å; F271-F530 HydrophobicContact CZ-CD2 3.91Å
272G92.9Very high96.8Very high1 Ų115.6 Ų15.61%0.019%0.094CC..THydrogen-bonded Turntrans63.2-135.7179.800000113D513 T526G272-D513 WeakPolarHBondContact CA-OD2 3.14Å; G272-T526 WeakPolarHBondContact CA-OG1 3.34Å
273D87Confident96.8Very high2 Ų217.5 Ų17.51%0.01111%0.111CC..THydrogen-bonded Turntrans-108.681.6-173.971.11.4000115H275 N287 T321 Y512 D513D273-H275 IonicContact OD1-CE1 2.78Å; D273-H275 PolarHBondContact OD1-CE1 3.34Å; D273-H275 VanDerWaalsContact OD1-CE1 3.26Å; D273-H275 IonicContact OD1-NE2 3.52Å; D273-N287 PolarHBondContact O-ND2 2.93Å; D273-N287 PolarHBondContact O-OD1 2.79Å; D273-T321 CarbonylContact C-O 3.57Å; D273-T321 WeakPolarHBondContact CA-O 3.36Å; D273-T321 WeakPolarHBondContact CB-O 3.4Å; D273-Y512 VanDerWaalsContact OD1-CD1 3.3Å; D273-Y512 WeakPolarHBondContact OD1-CD1 3.36Å; D273-Y512 VanDerWaalsContact OD1-CE1 3.23Å; D273-Y512 WeakPolarHBondContact OD1-CE1 3.42Å; D273-Y512 WeakPolarHBondContact OD2-CD1 3.12Å; D273-Y512 WeakPolarHBondContact OD2-CE1 3.29Å; D273-D513 PolarHBondContact N-OD2 3.48Å
274P93.9Very high96.8Very high0 Ų013 Ų130%09%0.089CC..THydrogen-bonded Turn-54.3128.8-90.47.111.1000114.5V270 F271 F276 F286 T308 T321V270-P274 HydrophobicContact CG1-CB 3.57Å; F271-P274 CarbonylContact O-C 3.55Å; F271-P274 WeakPolarHBondContact O-CA 3.17Å; P274-F276 HydrophobicContact CB-CE2 3.76Å; P274-F276 HydrophobicContact CB-CZ 4.11Å; P274-F276 HydrophobicContact CG-CE2 4.44Å; P274-F276 WeakPolarHBondContact O-CE2 3.34Å; P274-F286 WeakPolarHBondContact CD-O 3.46Å; P274-F286 PolarHBondContact O-N 2.83Å; P274-T308 HydrophobicContact CG-CG2 3.62Å; P274-T321 WeakPolarHBondContact CD-O 3.25Å; P274-T321 WeakPolarHBondContact CD-OG1 3.3Å
275H96.6Very high96.7Very high0 Ų014.3 Ų14.30%010%0.098CC..EExtended strand (participates in β ladder)trans-94.5153.9159.2-49.2-54.3000110.6V270 F271 D273 Y284 S285 F509 D513V270-H275 CarbonylContact C-O 3.6Å; V270-H275 VanDerWaalsContact CA-O 3.3Å; V270-H275 WeakPolarHBondContact CA-O 3.12Å; F271-H275 HydrophobicContact CD1-CB 4.27Å; F271-H275 HydrophobicContact CD2-CB 4.43Å; F271-H275 HydrophobicContact CE1-CB 3.8Å; F271-H275 HydrophobicContact CE2-CB 3.98Å; F271-H275 AromaticContact CE2-CD2 3.9Å; F271-H275 HydrophobicContact CZ-CB 3.63Å; F271-H275 PolarHBondContact N-O 3.47Å; F271-H275 PolarHBondContact O-N 3.07Å; D273-H275 IonicContact OD1-CE1 2.78Å; D273-H275 PolarHBondContact OD1-CE1 3.34Å; D273-H275 VanDerWaalsContact OD1-CE1 3.26Å; D273-H275 IonicContact OD1-NE2 3.52Å; H275-Y284 WeakPolarHBondContact CA-O 3.45Å; H275-S285 PolarHBondContact ND1-OG 2.89Å; H275-F509 HydrophobicContact CB-CD1 3.98Å; H275-F509 HydrophobicContact CB-CE1 4.2Å; H275-F509 HydrophobicContact CB-CG 4.44Å; H275-F509 VanDerWaalsContact CD2-CB 3.47Å; H275-F509 WeakPolarHBondContact CD2-CB 3.42Å; H275-F509 AromaticContact CD2-CD1 3.68Å; H275-F509 AromaticContact CD2-CG 3.78Å; H275-F509 AromaticContact CE1-CD1 3.72Å; H275-F509 AromaticContact CG-CD1 3.42Å; H275-F509 VanDerWaalsContact CG-CD1 3.42Å; H275-F509 AromaticContact CG-CG 3.93Å; H275-F509 AromaticContact ND1-CD1 3.45Å; H275-F509 WeakPolarHBondContact ND1-CD1 3.38Å; H275-F509 WeakPolarHBondContact NE2-CB 3.41Å; H275-F509 AromaticContact NE2-CD1 3.78Å; H275-F509 AromaticContact NE2-CG 4Å; H275-D513 IonicContact CD2-OD1 2.92Å; H275-D513 IonicContact CE1-OD1 2.73Å; H275-D513 IonicContact NE2-OD1 3.44Å; H275-D513 PolarHBondContact NE2-OD1 3.31Å; H275-D513 IonicContact NE2-OD2 2.67Å
276F98.3Very high96.6Very high4 Ų414.1 Ų14.12%0.01810%0.097CC..EExtended strand (participates in β ladder)trans-129.1142.3-175.3-65.3-103.5000109.9V269 V270 P274 S283 Y284 F286 L294 L414 L415V269-F276 CarbonylContact O-C 3.56Å; V269-F276 WeakPolarHBondContact O-CA 3.04Å; V270-F276 HydrophobicContact CB-CD1 4.41Å; V270-F276 HydrophobicContact CB-CE1 4.26Å; V270-F276 HydrophobicContact CG1-CD1 4.23Å; V270-F276 HydrophobicContact CG1-CE1 3.8Å; V270-F276 HydrophobicContact CG1-CE2 4.27Å; V270-F276 HydrophobicContact CG1-CZ 3.81Å; V270-F276 HydrophobicContact CG2-CD1 3.61Å; V270-F276 HydrophobicContact CG2-CE1 3.48Å; V270-F276 VanDerWaalsContact CG2-CE1 3.48Å; V270-F276 HydrophobicContact CG2-CZ 4.33Å; P274-F276 HydrophobicContact CB-CE2 3.76Å; P274-F276 HydrophobicContact CB-CZ 4.11Å; P274-F276 HydrophobicContact CG-CE2 4.44Å; P274-F276 WeakPolarHBondContact O-CE2 3.34Å; F276-S283 VanDerWaalsContact O-CA 3.3Å; F276-S283 WeakPolarHBondContact O-CA 3.46Å; F276-Y284 HydrophobicContact CB-CD1 3.89Å; F276-Y284 HydrophobicContact CB-CD2 4.4Å; F276-Y284 HydrophobicContact CB-CE1 3.39Å; F276-Y284 HydrophobicContact CB-CE2 3.93Å; F276-Y284 HydrophobicContact CB-CG 4.36Å; F276-Y284 WeakPolarHBondContact CD1-OH 3.4Å; F276-Y284 HydrophobicContact CD2-CD2 4.36Å; F276-Y284 AromaticContact CD2-CE2 3.7Å; F276-Y284 HydrophobicContact CD2-CE2 3.7Å; F276-Y284 AromaticContact CD2-CZ 3.9Å; F276-Y284 HydrophobicContact CE2-CE2 4.42Å; F276-Y284 HydrophobicContact CG-CE1 4.07Å; F276-Y284 AromaticContact CG-CE2 3.84Å; F276-Y284 HydrophobicContact CG-CE2 3.84Å; F276-Y284 AromaticContact CG-CZ 3.51Å; F276-Y284 WeakPolarHBondContact CG-OH 3.41Å; F276-Y284 PolarHBondContact N-O 3.23Å; F276-Y284 PolarHBondContact O-N 2.72Å; F276-F286 HydrophobicContact CD2-CB 4.23Å; F276-F286 HydrophobicContact CE2-CB 3.78Å; F276-F286 HydrophobicContact CE2-CD1 4.26Å; F276-F286 HydrophobicContact CZ-CD1 4.31Å; F276-L294 HydrophobicContact CE1-CD2 4.05Å; F276-L414 HydrophobicContact CD1-CB 4.15Å; F276-L414 HydrophobicContact CE1-CB 3.87Å; F276-L414 HydrophobicContact CE1-CD1 3.89Å; F276-L414 HydrophobicContact CZ-CD1 4Å; F276-L415 HydrophobicContact CD1-CD2 4.13Å
277I98.6Very high96.4Very high12 Ų1213 Ų136%0.0629%0.089CC..EExtended strand (participates in β ladder)trans-126.8118.9161.3-58.4167.6000106.5A268 V269 F271 V282 F530A268-I277 CarbonylContact C-O 3.52Å; A268-I277 VanDerWaalsContact CA-O 3.3Å; A268-I277 WeakPolarHBondContact CA-O 3.41Å; A268-I277 WeakPolarHBondContact CB-O 2.86Å; V269-I277 HydrophobicContact CG1-CB 3.87Å; V269-I277 HydrophobicContact CG1-CD1 4.04Å; V269-I277 HydrophobicContact CG1-CG1 4.18Å; V269-I277 PolarHBondContact N-O 3.24Å; V269-I277 PolarHBondContact O-N 3.38Å; F271-I277 HydrophobicContact CE1-CD1 3.94Å; F271-I277 HydrophobicContact CE1-CG1 4.01Å; F271-I277 HydrophobicContact CZ-CD1 4.27Å; I277-V282 WeakPolarHBondContact CA-O 3.45Å; I277-F530 HydrophobicContact CD1-CD2 4.01Å; I277-F530 HydrophobicContact CD1-CE2 3.9Å
278T98.7Very high96.3Very high1 Ų112.6 Ų12.61%0.0069%0.086CC..  trans-73.4170.6-179.663.60000111.8D280 G281 V282 Y284 L415 D425T278-D280 PolarHBondContact O-N 2.84Å; T278-G281 PolarHBondContact O-N 2.89Å; T278-G281 PolarHBondContact OG1-N 3.01Å; T278-V282 HydrophobicContact CG2-CB 4.02Å; T278-V282 PolarHBondContact N-O 3.27Å; T278-V282 WeakPolarHBondContact OG1-CB 3.16Å; T278-V282 PolarHBondContact OG1-N 3.37Å; T278-Y284 HydrophobicContact CG2-CE1 4.01Å; T278-L415 WeakPolarHBondContact CA-O 3.13Å; T278-L415 VanDerWaalsContact CB-O 3.25Å; T278-L415 WeakPolarHBondContact CB-O 3.15Å; T278-D425 WeakPolarHBondContact CB-OD2 3.46Å; T278-D425 HydrophobicContact CG2-CB 4.19Å; T278-D425 PolarHBondContact OG1-OD2 3.46Å
279F98.5Very high96.2Very high17 Ų1715.5 Ų15.58%0.07510%0.098CC..THydrogen-bonded Turntrans-60.1-28.7177.9-65.1-72.3000113.6A268 V295 V401 L403 L415 M418A268-F279 HydrophobicContact CB-CD1 3.53Å; A268-F279 HydrophobicContact CB-CD2 4.04Å; A268-F279 HydrophobicContact CB-CE1 3.5Å; A268-F279 HydrophobicContact CB-CE2 4.01Å; A268-F279 HydrophobicContact CB-CG 3.79Å; A268-F279 HydrophobicContact CB-CZ 3.74Å; F279-V295 HydrophobicContact CE2-CB 4.48Å; F279-V295 HydrophobicContact CE2-CG2 4.03Å; F279-V401 HydrophobicContact CE1-CB 4.45Å; F279-V401 HydrophobicContact CE1-CG1 4.43Å; F279-V401 HydrophobicContact CZ-CB 4.17Å; F279-V401 HydrophobicContact CZ-CG1 4.01Å; F279-L403 HydrophobicContact CE1-CB 4.16Å; F279-L403 HydrophobicContact CE1-CD1 3.84Å; F279-L403 HydrophobicContact CE1-CG 3.76Å; F279-L403 HydrophobicContact CE2-CD1 3.75Å; F279-L403 HydrophobicContact CZ-CB 4.47Å; F279-L403 HydrophobicContact CZ-CD1 3.3Å; F279-L403 HydrophobicContact CZ-CG 3.65Å; F279-L415 HydrophobicContact CD2-CB 4.17Å; F279-L415 WeakPolarHBondContact CD2-O 3.31Å; F279-L415 HydrophobicContact CE2-CB 3.68Å; F279-L415 HydrophobicContact CZ-CB 4.32Å; F279-L415 HydrophobicContact CZ-CD1 4.38Å; F279-L415 PolarHBondContact N-O 2.92Å; F279-M418 HydrophobicContact CB-CB 3.81Å; F279-M418 HydrophobicContact CB-CG 3.73Å; F279-M418 HydrophobicContact CB-SD 4.47Å; F279-M418 HydrophobicContact CD1-SD 4.22Å; F279-M418 HydrophobicContact CD2-CB 3.99Å; F279-M418 HydrophobicContact CG-CB 3.97Å; F279-M418 HydrophobicContact CG-CG 4.05Å; F279-M418 HydrophobicContact CG-SD 4.25Å
280D98.1Very high96.1Very high35 Ų3515.6 Ų15.619%0.18710%0.099CC..THydrogen-bonded Turntrans-99.411.5178.7-57.9-24000112.7T278 K417 N419 G420 D421 D425T278-D280 PolarHBondContact O-N 2.84Å; D280-K417 VanDerWaalsContact OD2-O 3.04Å; D280-N419 PolarHBondContact OD1-N 3.38Å; D280-N419 PolarHBondContact OD2-N 2.9Å; D280-N419 PolarHBondContact OD2-OD1 3.15Å; D280-G420 WeakPolarHBondContact OD1-CA 3.38Å; D280-G420 PolarHBondContact OD1-N 3.41Å; D280-G420 WeakPolarHBondContact OD2-CA 3.37Å; D280-G420 PolarHBondContact OD2-N 2.78Å; D280-D421 PolarHBondContact OD2-N 3.35Å; D280-D425 WeakPolarHBondContact CB-OD2 3.18Å
281G97.1Very high96.1Very high46 Ų4615.5 Ų15.547%0.47410%0.098SC..  trans909.4168.100000116.1T278 S283T278-G281 PolarHBondContact O-N 2.89Å; T278-G281 PolarHBondContact OG1-N 3.01Å; G281-S283 PolarHBondContact O-N 2.94Å
282V97.3Very high96.2Very high18 Ų1815.6 Ų15.611%0.10910%0.099CC..  trans-68.9122.1174.1-178.60000109.6I277 T278 Y284 A422 D425 L426I277-V282 WeakPolarHBondContact CA-O 3.45Å; T278-V282 HydrophobicContact CG2-CB 4.02Å; T278-V282 PolarHBondContact N-O 3.27Å; T278-V282 WeakPolarHBondContact OG1-CB 3.16Å; T278-V282 PolarHBondContact OG1-N 3.37Å; V282-Y284 HydrophobicContact CG1-CD1 4.42Å; V282-A422 HydrophobicContact CG2-CB 3.56Å; V282-A422 WeakPolarHBondContact CG2-O 3.36Å; V282-D425 HydrophobicContact CB-CB 4.33Å; V282-D425 HydrophobicContact CG2-CB 3.83Å; V282-D425 WeakPolarHBondContact CG2-OD2 3.3Å; V282-L426 HydrophobicContact CG1-CD1 3.94Å; V282-L426 HydrophobicContact CG1-CD2 3.98Å; V282-L426 HydrophobicContact CG1-CG 3.97Å
283S96.4Very high96.4Very high63 Ų6316.2 Ų16.244%0.44110%0.103SC..EExtended strand (participates in β ladder)trans-104.6128.9178.6-54.60000111.1F276 G281F276-S283 VanDerWaalsContact O-CA 3.3Å; F276-S283 WeakPolarHBondContact O-CA 3.46Å; G281-S283 PolarHBondContact O-N 2.94Å
284Y95.8Very high97Very high10 Ų1016.3 Ų16.34%0.03910%0.103CC..EExtended strand (participates in β ladder)trans-155.6169.9178.971.8-85000111.8H275 F276 T278 V282 F286 L414 L426 F446H275-Y284 WeakPolarHBondContact CA-O 3.45Å; F276-Y284 HydrophobicContact CB-CD1 3.89Å; F276-Y284 HydrophobicContact CB-CD2 4.4Å; F276-Y284 HydrophobicContact CB-CE1 3.39Å; F276-Y284 HydrophobicContact CB-CE2 3.93Å; F276-Y284 HydrophobicContact CB-CG 4.36Å; F276-Y284 WeakPolarHBondContact CD1-OH 3.4Å; F276-Y284 HydrophobicContact CD2-CD2 4.36Å; F276-Y284 AromaticContact CD2-CE2 3.7Å; F276-Y284 HydrophobicContact CD2-CE2 3.7Å; F276-Y284 AromaticContact CD2-CZ 3.9Å; F276-Y284 HydrophobicContact CE2-CE2 4.42Å; F276-Y284 HydrophobicContact CG-CE1 4.07Å; F276-Y284 AromaticContact CG-CE2 3.84Å; F276-Y284 HydrophobicContact CG-CE2 3.84Å; F276-Y284 AromaticContact CG-CZ 3.51Å; F276-Y284 WeakPolarHBondContact CG-OH 3.41Å; F276-Y284 PolarHBondContact N-O 3.23Å; F276-Y284 PolarHBondContact O-N 2.72Å; T278-Y284 HydrophobicContact CG2-CE1 4.01Å; V282-Y284 HydrophobicContact CG1-CD1 4.42Å; Y284-F286 HydrophobicContact CD2-CB 4.38Å; Y284-F286 HydrophobicContact CE2-CB 3.94Å; Y284-L414 WeakPolarHBondContact OH-CB 3.23Å; Y284-L414 PolarHBondContact OH-O 3.23Å; Y284-L426 HydrophobicContact CD1-CD2 3.73Å; Y284-L426 HydrophobicContact CE1-CD2 3.73Å; Y284-L426 HydrophobicContact CG-CD2 4.39Å; Y284-F446 HydrophobicContact CD2-CE1 4.29Å; Y284-F446 HydrophobicContact CE1-CE1 4.25Å; Y284-F446 HydrophobicContact CE2-CD1 4.34Å; Y284-F446 AromaticContact CE2-CE1 3.61Å; Y284-F446 HydrophobicContact CE2-CE1 3.61Å; Y284-F446 AromaticContact CZ-CE1 3.59Å
285S94.9Very high97.2Very high43 Ų4316.3 Ų16.330%0.30110%0.103SC..EExtended strand (participates in β ladder)trans-117.3138.1177.3-57.30000110.8H275H275-S285 PolarHBondContact ND1-OG 2.89Å
286F95.6Very high97.3Very high3 Ų320.2 Ų20.21%0.01312%0.118CC..  trans-142.1106.3174.4168.7-117.4000111.2P274 F276 Y284 G288 Y292 L414 F444P274-F286 WeakPolarHBondContact CD-O 3.46Å; P274-F286 PolarHBondContact O-N 2.83Å; F276-F286 HydrophobicContact CD2-CB 4.23Å; F276-F286 HydrophobicContact CE2-CB 3.78Å; F276-F286 HydrophobicContact CE2-CD1 4.26Å; F276-F286 HydrophobicContact CZ-CD1 4.31Å; Y284-F286 HydrophobicContact CD2-CB 4.38Å; Y284-F286 HydrophobicContact CE2-CB 3.94Å; F286-G288 PolarHBondContact O-N 2.82Å; F286-Y292 AromaticContact CE1-CD1 3.78Å; F286-Y292 HydrophobicContact CE1-CD1 3.78Å; F286-Y292 AromaticContact CE1-CD2 3.94Å; F286-Y292 HydrophobicContact CE1-CD2 3.94Å; F286-Y292 AromaticContact CE1-CE1 3.69Å; F286-Y292 HydrophobicContact CE1-CE1 3.69Å; F286-Y292 AromaticContact CE1-CE2 3.84Å; F286-Y292 HydrophobicContact CE1-CE2 3.84Å; F286-Y292 AromaticContact CE1-CG 3.91Å; F286-Y292 HydrophobicContact CE1-CG 3.91Å; F286-Y292 AromaticContact CE1-CZ 3.72Å; F286-Y292 HydrophobicContact CZ-CD1 4.04Å; F286-Y292 AromaticContact CZ-CE1 3.52Å; F286-Y292 HydrophobicContact CZ-CE1 3.52Å; F286-Y292 HydrophobicContact CZ-CE2 4.18Å; F286-Y292 AromaticContact CZ-CZ 3.6Å; F286-L414 HydrophobicContact CD1-CD1 4.19Å; F286-L414 HydrophobicContact CE1-CD1 4.35Å; F286-F444 AromaticContact CD2-CD2 3.93Å; F286-F444 HydrophobicContact CD2-CD2 3.93Å; F286-F444 AromaticContact CE2-CD2 3.78Å; F286-F444 HydrophobicContact CE2-CD2 3.78Å; F286-F444 HydrophobicContact CE2-CE2 4.02Å; F286-F444 HydrophobicContact CE2-CG 4.34Å; F286-F444 WeakPolarHBondContact CE2-O 3.45Å
287N94.2Very high97.3Very high7 Ų720.1 Ų20.14%0.03712%0.117CC..  trans-99.653.4-178.1-89.5-83.5000112.6D273 T321 F480 P482 Y512D273-N287 PolarHBondContact O-ND2 2.93Å; D273-N287 PolarHBondContact O-OD1 2.79Å; N287-T321 WeakPolarHBondContact CA-OG1 3.29Å; N287-T321 PolarHBondContact OD1-N 2.76Å; N287-T321 PolarHBondContact OD1-O 2.76Å; N287-T321 PolarHBondContact OD1-OG1 3.14Å; N287-F480 VanDerWaalsContact O-CE1 3.28Å; N287-F480 WeakPolarHBondContact O-CE1 3.48Å; N287-P482 HydrophobicContact CB-CB 3.39Å; N287-P482 HydrophobicContact CB-CG 3.82Å; N287-Y512 PolarHBondContact ND2-OH 3.29Å
288G95.6Very high97.2Very high0 Ų026.1 Ų26.10%015%0.145CC..  trans-79144.7174.500000111.9F286 Y292 T308 T321F286-G288 PolarHBondContact O-N 2.82Å; G288-Y292 VanDerWaalsContact C-OH 3.27Å; G288-Y292 WeakPolarHBondContact CA-OH 3.31Å; G288-T308 WeakPolarHBondContact O-CB 3.19Å; G288-T308 PolarHBondContact O-OG1 3.32Å; G288-T321 PolarHBondContact O-OG1 2.83Å
289K96.3Very high96.9Very high60 Ų6029.5 Ų29.526%0.26118%0.18SC..SBendtrans-92.3113.9166.7171.7-174.1167.9-158.90109Y292 P310 T321 D477 F480K289-Y292 VanDerWaalsContact C-OH 3.26Å; K289-Y292 PolarHBondContact N-OH 2.75Å; K289-Y292 PolarHBondContact O-OH 2.91Å; K289-Y292 VanDerWaalsContact O-OH 3.12Å; K289-P310 HydrophobicContact CD-CG 3.88Å; K289-P310 HydrophobicContact CG-CG 4.24Å; K289-T321 HydrophobicContact CB-CG2 4.21Å; K289-D477 HydrophobicContact CB-CB 4.24Å; K289-D477 HydrophobicContact CD-CB 3.93Å; K289-D477 WeakPolarHBondContact CD-OD2 3.48Å; K289-D477 WeakPolarHBondContact CE-OD2 3.34Å; K289-D477 HydrophobicContact CG-CB 4.17Å; K289-D477 IonicContact NZ-OD2 3.27Å; K289-D477 PolarHBondContact NZ-OD2 3.38Å; K289-D477 PolarHBondContact O-N 3.4Å; K289-F480 HydrophobicContact CB-CB 3.89Å; K289-F480 HydrophobicContact CB-CD1 3.83Å; K289-F480 HydrophobicContact CB-CD2 4.13Å; K289-F480 HydrophobicContact CB-CE1 4.42Å; K289-F480 HydrophobicContact CB-CG 3.66Å; K289-F480 HydrophobicContact CD-CB 4.23Å; K289-F480 HydrophobicContact CD-CD2 4.14Å; K289-F480 HydrophobicContact CD-CG 4.27Å
290G96.9Very high96.8Very high2 Ų232.2 Ų32.22%0.02119%0.192CC..EExtended strand (participates in β ladder)trans160.2-160.4-173.400000116.3R307 T308 R475G290-R307 WeakPolarHBondContact O-CA 3.33Å; G290-T308 PolarHBondContact N-O 2.97Å; G290-T308 PolarHBondContact N-OG1 3.44Å; G290-T308 PolarHBondContact O-N 3.35Å; G290-T308 PolarHBondContact O-OG1 3.03Å; G290-R475 CarbonylContact C-O 3.42Å; G290-R475 WeakPolarHBondContact CA-O 3.39Å
291E98.3Very high96.8Very high0 Ų036.7 Ų36.70%021%0.212CC..EExtended strand (participates in β ladder)trans-124.9126.9174.4-68.1177.5165.200109.4G306 R307 A451 V452 F459 Y461 Y470 R475E291-G306 CarbonylContact C-O 3.53Å; E291-G306 WeakPolarHBondContact CA-O 3.37Å; E291-R307 HydrophobicContact CG-CB 4Å; E291-R307 HydrophobicContact CG-CG 3.89Å; E291-R307 IonicContact OE1-CZ 2.67Å; E291-R307 IonicContact OE1-NE 3.37Å; E291-R307 PolarHBondContact OE1-NE 3.21Å; E291-R307 IonicContact OE1-NH2 3.53Å; E291-R307 PolarHBondContact OE1-NH2 3.44Å; E291-A451 WeakPolarHBondContact O-CA 3.29Å; E291-V452 HydrophobicContact CB-CB 4.34Å; E291-V452 HydrophobicContact CB-CG2 4.32Å; E291-V452 PolarHBondContact O-N 2.87Å; E291-F459 HydrophobicContact CB-CD2 4.48Å; E291-F459 HydrophobicContact CB-CE2 4.01Å; E291-F459 VanDerWaalsContact CD-CD2 3.44Å; E291-F459 HydrophobicContact CG-CD2 4.08Å; E291-F459 HydrophobicContact CG-CE2 3.89Å; E291-F459 WeakPolarHBondContact OE1-CD2 3.48Å; E291-Y461 WeakPolarHBondContact OE1-CE1 3.47Å; E291-Y461 PolarHBondContact OE1-OH 3.01Å; E291-Y461 PolarHBondContact OE2-OH 3.47Å; E291-Y470 HydrophobicContact CG-CD1 3.96Å; E291-Y470 HydrophobicContact CG-CE1 4.44Å; E291-Y470 HydrophobicContact CG-CG 4.46Å; E291-R475 PolarHBondContact N-O 2.03Å; E291-R475 IonicContact OE1-NH1 3.55Å; E291-R475 WeakPolarHBondContact OE2-CD 3.26Å; E291-R475 IonicContact OE2-CZ 2.8Å; E291-R475 IonicContact OE2-NE 3.53Å; E291-R475 IonicContact OE2-NH1 3.54Å; E291-R475 PolarHBondContact OE2-NH1 2.85Å
292Y98.6Very high96.8Very high4 Ų434.5 Ų34.52%0.01619%0.189CC..EExtended strand (participates in β ladder)trans-132148.4-169.9-52.6-83.5000112.3F286 G288 K289 L294 Q305 G306 T308 L414 W450 A451 H476F286-Y292 AromaticContact CE1-CD1 3.78Å; F286-Y292 HydrophobicContact CE1-CD1 3.78Å; F286-Y292 AromaticContact CE1-CD2 3.94Å; F286-Y292 HydrophobicContact CE1-CD2 3.94Å; F286-Y292 AromaticContact CE1-CE1 3.69Å; F286-Y292 HydrophobicContact CE1-CE1 3.69Å; F286-Y292 AromaticContact CE1-CE2 3.84Å; F286-Y292 HydrophobicContact CE1-CE2 3.84Å; F286-Y292 AromaticContact CE1-CG 3.91Å; F286-Y292 HydrophobicContact CE1-CG 3.91Å; F286-Y292 AromaticContact CE1-CZ 3.72Å; F286-Y292 HydrophobicContact CZ-CD1 4.04Å; F286-Y292 AromaticContact CZ-CE1 3.52Å; F286-Y292 HydrophobicContact CZ-CE1 3.52Å; F286-Y292 HydrophobicContact CZ-CE2 4.18Å; F286-Y292 AromaticContact CZ-CZ 3.6Å; G288-Y292 VanDerWaalsContact C-OH 3.27Å; G288-Y292 WeakPolarHBondContact CA-OH 3.31Å; K289-Y292 VanDerWaalsContact C-OH 3.26Å; K289-Y292 PolarHBondContact N-OH 2.75Å; K289-Y292 PolarHBondContact O-OH 2.91Å; K289-Y292 VanDerWaalsContact O-OH 3.12Å; Y292-L294 PolarHBondContact O-N 2.81Å; Y292-Q305 CarbonylContact O-C 3.55Å; Y292-Q305 VanDerWaalsContact O-CA 3.26Å; Y292-Q305 WeakPolarHBondContact O-CA 3.33Å; Y292-G306 PolarHBondContact N-O 2.78Å; Y292-G306 PolarHBondContact O-N 2.77Å; Y292-T308 WeakPolarHBondContact CE2-OG1 3.43Å; Y292-L414 HydrophobicContact CG-CD1 4.27Å; Y292-W450 WeakPolarHBondContact CA-O 3.48Å; Y292-A451 HydrophobicContact CD1-CB 4.41Å; Y292-A451 HydrophobicContact CE1-CB 4.39Å; Y292-H476 HydrophobicContact CE1-CB 4.16Å; Y292-H476 AromaticContact CE1-ND1 3.83Å; Y292-H476 AromaticContact CZ-ND1 3.76Å; Y292-H476 PolarHBondContact OH-ND1 2.88Å
293T98.8Very high96.9Very high14 Ų1435.1 Ų35.19%0.08619%0.193CC..EExtended strand (participates in β ladder)trans-76.3110.3172.5-59.70000109.4R296 L414 W450T293-R296 HydrophobicContact CG2-CB 3.97Å; T293-L414 WeakPolarHBondContact O-CG 3.28Å; T293-L414 PolarHBondContact O-N 3.12Å; T293-W450 PolarHBondContact N-O 3.47Å
294L98.9Very high97Very high4 Ų432.1 Ų32.12%0.02117%0.172CC..EExtended strand (participates in β ladder)trans-73.3-52.5175.8-58.2-173.1000110V270 F276 Y292 V304 V326 T399 G413 L414 L415V270-L294 HydrophobicContact CG2-CD1 4.16Å; V270-L294 HydrophobicContact CG2-CD2 4.1Å; F276-L294 HydrophobicContact CE1-CD2 4.05Å; Y292-L294 PolarHBondContact O-N 2.81Å; L294-V304 HydrophobicContact CB-CG1 4.39Å; L294-V304 WeakPolarHBondContact CB-O 3.25Å; L294-V304 HydrophobicContact CD1-CG1 4.21Å; L294-V304 PolarHBondContact N-O 3.31Å; L294-V326 HydrophobicContact CD1-CG1 4.49Å; L294-T399 HydrophobicContact CD1-CG2 4.5Å; L294-G413 CarbonylContact O-C 3.58Å; L294-L414 HydrophobicContact CD2-CD1 4.19Å; L294-L414 PolarHBondContact O-N 3.11Å; L294-L415 HydrophobicContact CB-CD1 4.12Å; L294-L415 HydrophobicContact CB-CG 4.27Å; L294-L415 WeakPolarHBondContact O-CB 3.46Å; L294-L415 WeakPolarHBondContact O-CG 3.36Å; L294-L415 PolarHBondContact O-N 3.36Å
295V98.8Very high97.2Very high0 Ų031.8 Ų31.80%017%0.171CC..EExtended strand (participates in β ladder)trans-151.6143.617461.10000110.8F279 V304 V401 L403 T411 V412 L415F279-V295 HydrophobicContact CE2-CB 4.48Å; F279-V295 HydrophobicContact CE2-CG2 4.03Å; V295-V304 HydrophobicContact CG1-CB 3.81Å; V295-V304 HydrophobicContact CG1-CG2 3.8Å; V295-V304 PolarHBondContact N-O 3.38Å; V295-V304 PolarHBondContact O-N 2.75Å; V295-V401 HydrophobicContact CG1-CG1 4.16Å; V295-V401 HydrophobicContact CG1-CG2 4.45Å; V295-L403 HydrophobicContact CG2-CD1 4.25Å; V295-T411 HydrophobicContact CG2-CG2 4.05Å; V295-V412 CarbonylContact C-O 3.56Å; V295-V412 WeakPolarHBondContact CA-O 3.45Å; V295-L415 HydrophobicContact CB-CB 4.36Å; V295-L415 HydrophobicContact CB-CD1 4.22Å; V295-L415 HydrophobicContact CG1-CD1 4.17Å
296R98.2Very high97.3Very high82 Ų8229.8 Ų29.831%0.30916%0.157SC..EExtended strand (participates in β ladder)trans-137.1140172.9-173.4174.766.490.73.9109.7T293 E298 L302 T411 V412T293-R296 HydrophobicContact CG2-CB 3.97Å; R296-E298 IonicContact CZ-OE1 3.64Å; R296-E298 VanDerWaalsContact NH1-CD 3.31Å; R296-E298 IonicContact NH1-OE1 3.49Å; R296-E298 PolarHBondContact NH1-OE1 3.24Å; R296-E298 IonicContact NH2-OE1 3.64Å; R296-E298 PolarHBondContact NH2-OE1 3.06Å; R296-L302 WeakPolarHBondContact CA-O 3.4Å; R296-T411 WeakPolarHBondContact O-CA 3.39Å; R296-V412 HydrophobicContact CB-CG2 4.2Å; R296-V412 PolarHBondContact N-O 2.93Å; R296-V412 PolarHBondContact O-N 3.42Å
297S98.1Very high97.5Very high1 Ų129.8 Ų29.81%0.00716%0.157CC..EExtended strand (participates in β ladder)trans-132.7113.8168.71740000108.8Q301 L302 S410S297-Q301 CarbonylContact O-C 3.54Å; S297-Q301 VanDerWaalsContact O-CA 3.29Å; S297-Q301 WeakPolarHBondContact O-CA 3.23Å; S297-Q301 PolarHBondContact O-N 3.08Å; S297-L302 PolarHBondContact N-O 3.42Å; S297-L302 PolarHBondContact O-N 2.92Å; S297-S410 WeakPolarHBondContact CA-O 3.37Å; S297-S410 PolarHBondContact OG-OG 3.49Å
298E95.5Very high97.6Very high139 Ų13929.8 Ų29.865%0.6516%0.157SC*.THydrogen-bonded Turntrans-66-43.8-179.1-68.9-175.8178.800111.8R296 K300 Q301R296-E298 IonicContact CZ-OE1 3.64Å; R296-E298 VanDerWaalsContact NH1-CD 3.31Å; R296-E298 IonicContact NH1-OE1 3.49Å; R296-E298 PolarHBondContact NH1-OE1 3.24Å; R296-E298 IonicContact NH2-OE1 3.64Å; R296-E298 PolarHBondContact NH2-OE1 3.06Å; E298-K300 VanDerWaalsContact C-N 3.27Å; E298-K300 PolarHBondContact O-N 2.85Å; E298-Q301 WeakPolarHBondContact O-CG 3.49Å; E298-Q301 PolarHBondContact O-N 2.89Å
299G94.1Very high97.5Very high72 Ų7232.7 Ų32.774%0.74217%0.171SC*.THydrogen-bonded Turntrans-63.5-32.9-177.600000113.2
300K94.9Very high97.3Very high74 Ų7431.3 Ų31.332%0.32217%0.168SC..THydrogen-bonded Turntrans-95.2-6174.7-60-65.4-172.91720113E298 L302 E406 F407E298-K300 VanDerWaalsContact C-N 3.27Å; E298-K300 PolarHBondContact O-N 2.85Å; K300-L302 PolarHBondContact O-N 3.45Å; K300-E406 WeakPolarHBondContact CE-O 3.43Å; K300-F407 HydrophobicContact CB-CD1 4.17Å; K300-F407 HydrophobicContact CB-CE1 3.41Å; K300-F407 VanDerWaalsContact CB-CE1 3.41Å; K300-F407 HydrophobicContact CB-CZ 3.63Å; K300-F407 HydrophobicContact CD-CZ 4.36Å; K300-F407 HydrophobicContact CG-CD1 3.83Å; K300-F407 HydrophobicContact CG-CD2 4.4Å; K300-F407 HydrophobicContact CG-CE1 3.49Å; K300-F407 VanDerWaalsContact CG-CE1 3.49Å; K300-F407 HydrophobicContact CG-CE2 4.09Å; K300-F407 HydrophobicContact CG-CG 4.28Å; K300-F407 HydrophobicContact CG-CZ 3.63Å
301Q97.8Very high96.8Very high129 Ų12931.5 Ų31.560%0.60317%0.169SC*.THydrogen-bonded Turntrans53.830.2-174.1-57.517557.500113.4S297 E298 E330 G331S297-Q301 CarbonylContact O-C 3.54Å; S297-Q301 VanDerWaalsContact O-CA 3.29Å; S297-Q301 WeakPolarHBondContact O-CA 3.23Å; S297-Q301 PolarHBondContact O-N 3.08Å; E298-Q301 WeakPolarHBondContact O-CG 3.49Å; E298-Q301 PolarHBondContact O-N 2.89Å; Q301-E330 WeakPolarHBondContact O-CA 3.26Å; Q301-G331 PolarHBondContact O-N 2.9Å
302L98.7Very high95.9Very high0 Ų039.6 Ų39.60%020%0.204CC..EExtended strand (participates in β ladder)trans-88.2135.1177.2-178.669.8000109.7R296 S297 K300 V304 E330 F382 A386 L403 F407R296-L302 WeakPolarHBondContact CA-O 3.4Å; S297-L302 PolarHBondContact N-O 3.42Å; S297-L302 PolarHBondContact O-N 2.92Å; K300-L302 PolarHBondContact O-N 3.45Å; L302-V304 HydrophobicContact CD1-CG2 4.46Å; L302-V304 HydrophobicContact CG-CG2 4.43Å; L302-E330 HydrophobicContact CD1-CB 4.21Å; L302-F382 HydrophobicContact CD1-CD2 3.83Å; L302-F382 HydrophobicContact CD1-CE2 3.94Å; L302-F382 HydrophobicContact CD1-CG 4.42Å; L302-A386 HydrophobicContact CD1-CB 4.24Å; L302-A386 HydrophobicContact CD2-CB 3.72Å; L302-L403 HydrophobicContact CD2-CD2 3.55Å; L302-F407 HydrophobicContact CB-CE1 3.93Å; L302-F407 HydrophobicContact CB-CZ 4.44Å; L302-F407 HydrophobicContact CD2-CD1 4.48Å; L302-F407 HydrophobicContact CD2-CE1 3.59Å; L302-F407 HydrophobicContact CD2-CZ 3.96Å; L302-F407 HydrophobicContact CG-CE1 4.42Å
303T98.8Very high94.5Very high31 Ų3142.6 Ų42.619%0.1922%0.22CC..EExtended strand (participates in β ladder)trans-137.9129.8172-60.90000109.7Q305 M328 K329 L458T303-Q305 HydrophobicContact CG2-CG 4.04Å; T303-M328 VanDerWaalsContact O-CA 3.26Å; T303-M328 WeakPolarHBondContact O-CA 3.27Å; T303-K329 PolarHBondContact N-O 3.12Å; T303-K329 PolarHBondContact O-N 2.86Å; T303-L458 HydrophobicContact CG2-CD1 3.9Å
304V98.9Very high92.6Very high0 Ų047.3 Ų47.30%025%0.254CS..EExtended strand (participates in β ladder)trans-129.3124.9173.9-172.40000108.4L294 V295 L302 V326 A327 M328 V388 V401L294-V304 HydrophobicContact CB-CG1 4.39Å; L294-V304 WeakPolarHBondContact CB-O 3.25Å; L294-V304 HydrophobicContact CD1-CG1 4.21Å; L294-V304 PolarHBondContact N-O 3.31Å; V295-V304 HydrophobicContact CG1-CB 3.81Å; V295-V304 HydrophobicContact CG1-CG2 3.8Å; V295-V304 PolarHBondContact N-O 3.38Å; V295-V304 PolarHBondContact O-N 2.75Å; L302-V304 HydrophobicContact CD1-CG2 4.46Å; L302-V304 HydrophobicContact CG-CG2 4.43Å; V304-V326 HydrophobicContact CG1-CG1 3.82Å; V304-A327 WeakPolarHBondContact CA-O 3.02Å; V304-M328 HydrophobicContact CG1-CB 4.37Å; V304-M328 HydrophobicContact CG2-CB 4.14Å; V304-V388 HydrophobicContact CG1-CG1 4.49Å; V304-V388 HydrophobicContact CG2-CG2 4Å; V304-V401 HydrophobicContact CG1-CG2 4.49Å
305Q98.9Very high90.7Very high2 Ų256.7 Ų56.71%0.00930%0.298CS..EExtended strand (participates in β ladder)trans-123.1147.1-177.2-65.9171.3-4.500110.2Y292 T303 V326 A327 V452 S456 F459Y292-Q305 CarbonylContact O-C 3.55Å; Y292-Q305 VanDerWaalsContact O-CA 3.26Å; Y292-Q305 WeakPolarHBondContact O-CA 3.33Å; T303-Q305 HydrophobicContact CG2-CG 4.04Å; Q305-V326 CarbonylContact O-C 3.58Å; Q305-V326 VanDerWaalsContact O-CA 3.26Å; Q305-V326 WeakPolarHBondContact O-CA 3.36Å; Q305-V326 WeakPolarHBondContact O-CG1 3.47Å; Q305-A327 PolarHBondContact N-O 2.91Å; Q305-A327 PolarHBondContact O-N 2.8Å; Q305-V452 HydrophobicContact CB-CG2 4.23Å; Q305-V452 HydrophobicContact CG-CG2 3.78Å; Q305-S456 PolarHBondContact NE2-O 3.21Å; Q305-F459 HydrophobicContact CB-CE2 3.7Å; Q305-F459 HydrophobicContact CB-CZ 3.79Å
306G98.5Very high89.3Confident1 Ų164.3 Ų64.31%0.0133%0.331CS..EExtended strand (participates in β ladder)trans-123.1137.5177.700000111.5E291 Y292 A325E291-G306 CarbonylContact C-O 3.53Å; E291-G306 WeakPolarHBondContact CA-O 3.37Å; Y292-G306 PolarHBondContact N-O 2.78Å; Y292-G306 PolarHBondContact O-N 2.77Å; G306-A325 CarbonylContact C-O 3.53Å; G306-A325 WeakPolarHBondContact CA-O 3.35Å
307R98.3Very high88Confident4 Ų464.2 Ų64.22%0.01534%0.339CS..EExtended strand (participates in β ladder)trans-103.7132.3171.4-177.4-174.2-69.4148.7-6.7109.7G290 E291 L323 T324 A325 E337 F459 Y470G290-R307 WeakPolarHBondContact O-CA 3.33Å; E291-R307 HydrophobicContact CG-CB 4Å; E291-R307 HydrophobicContact CG-CG 3.89Å; E291-R307 IonicContact OE1-CZ 2.67Å; E291-R307 IonicContact OE1-NE 3.37Å; E291-R307 PolarHBondContact OE1-NE 3.21Å; E291-R307 IonicContact OE1-NH2 3.53Å; E291-R307 PolarHBondContact OE1-NH2 3.44Å; R307-L323 WeakPolarHBondContact O-CA 3.41Å; R307-L323 WeakPolarHBondContact O-CD1 3.32Å; R307-T324 PolarHBondContact O-N 3Å; R307-T324 PolarHBondContact O-OG1 2.49Å; R307-A325 HydrophobicContact CB-CB 3.97Å; R307-A325 PolarHBondContact N-O 3.11Å; R307-A325 PolarHBondContact O-N 3.1Å; R307-E337 IonicContact NH1-OE1 3.67Å; R307-F459 HydrophobicContact CB-CE1 4.01Å; R307-F459 HydrophobicContact CB-CZ 4.03Å; R307-Y470 HydrophobicContact CG-CE1 4.18Å; R307-Y470 HydrophobicContact CG-CE2 4.37Å
308T96.9Very high87.1Confident6 Ų665.1 Ų65.14%0.03734%0.344CS..EExtended strand (participates in β ladder)trans-121.9134.6178.1550000111.1P274 G288 G290 Y292 K322 L323P274-T308 HydrophobicContact CG-CG2 3.62Å; G288-T308 WeakPolarHBondContact O-CB 3.19Å; G288-T308 PolarHBondContact O-OG1 3.32Å; G290-T308 PolarHBondContact N-O 2.97Å; G290-T308 PolarHBondContact N-OG1 3.44Å; G290-T308 PolarHBondContact O-N 3.35Å; G290-T308 PolarHBondContact O-OG1 3.03Å; Y292-T308 WeakPolarHBondContact CE2-OG1 3.43Å; T308-K322 CarbonylContact C-O 3.58Å; T308-K322 WeakPolarHBondContact CA-O 3.32Å; T308-L323 HydrophobicContact CG2-CD1 4.07Å
309E93.9Very high86.7Confident62 Ų6262.6 Ų62.629%0.2934%0.335SS..EExtended strand (participates in β ladder)trans-124.7153.7179.9-50-159.8134.600111.4T321 K322 T324 Y470E309-T321 CarbonylContact O-C 3.5Å; E309-T321 WeakPolarHBondContact O-CA 3.47Å; E309-T321 WeakPolarHBondContact O-CB 3.49Å; E309-K322 PolarHBondContact N-O 3.09Å; E309-K322 PolarHBondContact O-N 2.76Å; E309-T324 HydrophobicContact CB-CG2 3.76Å; E309-T324 HydrophobicContact CG-CG2 3.53Å; E309-T324 WeakPolarHBondContact CG-OG1 3.4Å; E309-Y470 WeakPolarHBondContact CG-OH 3.29Å; E309-Y470 WeakPolarHBondContact OE1-CE2 3.29Å; E309-Y470 PolarHBondContact OE1-OH 2.73Å
310P91.4Very high86.5Confident31 Ų3159.2 Ų59.220%0.20130%0.3CS..EExtended strand (participates in β ladder)trans-57.7139.1176.4-24.935.6000112.8K289 T317 A320 F480K289-P310 HydrophobicContact CD-CG 3.88Å; K289-P310 HydrophobicContact CG-CG 4.24Å; P310-T317 HydrophobicContact CB-CG2 3.63Å; P310-T317 HydrophobicContact CG-CG2 4.49Å; P310-A320 CarbonylContact C-O 3.54Å; P310-A320 WeakPolarHBondContact CA-O 3.48Å; P310-F480 HydrophobicContact CB-CE2 4.32Å; P310-F480 HydrophobicContact CG-CE2 4.12Å
311V86.1Confident86.4Confident6 Ų655.7 Ų55.74%0.03628%0.284CS..EExtended strand (participates in β ladder)trans-70.2135.5171.2-177.60000109I318 A320 K322 I522V311-I318 HydrophobicContact CB-CB 4.45Å; V311-I318 HydrophobicContact CG1-CD1 4.29Å; V311-I318 PolarHBondContact O-N 2.85Å; V311-A320 HydrophobicContact CG2-CB 4.4Å; V311-A320 PolarHBondContact N-O 2.03Å; V311-K322 HydrophobicContact CG2-CB 4.19Å; V311-K322 HydrophobicContact CG2-CD 4.36Å; V311-K322 HydrophobicContact CG2-CG 4.23Å; V311-I522 HydrophobicContact CG1-CD1 4.22Å
312K79.9Confident86.2Confident170 Ų17051.5 Ų51.574%0.73926%0.264SS*.EExtended strand (participates in β ladder)trans-111127.1177.3-64.4-178.9179.7178.70109.2
313D68.8Low86.1Confident66 Ų6651.6 Ų51.635%0.35327%0.265SS..EExtended strand (participates in β ladder)trans-119.8115.3169.317023.3000108.9E315 K316 I318D313-E315 PolarHBondContact O-N 3.15Å; D313-K316 PolarHBondContact N-O 2.86Å; D313-K316 WeakPolarHBondContact O-CA 3.3Å; D313-K316 WeakPolarHBondContact O-CB 3.37Å; D313-K316 PolarHBondContact O-N 3.45Å; D313-I318 HydrophobicContact CB-CD1 3.74Å; D313-I318 HydrophobicContact CB-CG1 4.2Å
314S58.8Low86Confident114 Ų11450.9 Ų50.980%0.79726%0.26SS*.THydrogen-bonded Turntrans47.745168.9-50.60000113.7K316S314-K316 VanDerWaalsContact C-N 3.29Å; S314-K316 PolarHBondContact O-N 3.01Å
315E60Low86Confident201 Ų20150.9 Ų50.994%0.93926%0.26SS*.THydrogen-bonded Turntrans74.2-8.2-174.5-51.4-165.7158.300117.4D313D313-E315 PolarHBondContact O-N 3.15Å
316K68.6Low86Confident160 Ų16050.8 Ų50.870%0.69626%0.26SS*.EExtended strand (participates in β ladder)trans-87129.5171.1-163.4175.4-179.8-177.30110.4D313 S314D313-K316 PolarHBondContact N-O 2.86Å; D313-K316 WeakPolarHBondContact O-CA 3.3Å; D313-K316 WeakPolarHBondContact O-CB 3.37Å; D313-K316 PolarHBondContact O-N 3.45Å; S314-K316 VanDerWaalsContact C-N 3.29Å; S314-K316 PolarHBondContact O-N 3.01Å
317T71.2Confident86Confident79 Ų7950.7 Ų50.749%0.48526%0.259SS..EExtended strand (participates in β ladder)trans-78.8126.4171.8-55.90000108.7P310P310-T317 HydrophobicContact CB-CG2 3.63Å; P310-T317 HydrophobicContact CG-CG2 4.49Å
318I79.6Confident86Confident21 Ų2150.5 Ų50.511%0.10826%0.258CS..EExtended strand (participates in β ladder)trans-88142.9171.9-58177.8000107.4V311 D313 A320 V516 G517 R518V311-I318 HydrophobicContact CB-CB 4.45Å; V311-I318 HydrophobicContact CG1-CD1 4.29Å; V311-I318 PolarHBondContact O-N 2.85Å; D313-I318 HydrophobicContact CB-CD1 3.74Å; D313-I318 HydrophobicContact CB-CG1 4.2Å; I318-A320 HydrophobicContact CG2-CB 3.95Å; I318-A320 PolarHBondContact O-N 3.32Å; I318-V516 HydrophobicContact CG2-CG1 4.42Å; I318-V516 WeakPolarHBondContact CG2-O 3.46Å; I318-G517 WeakPolarHBondContact CD1-O 3.04Å; I318-R518 HydrophobicContact CD1-CB 4.36Å; I318-R518 HydrophobicContact CD1-CG 4.43Å
319N86.9Confident86.1Confident86 Ų8653.3 Ų53.346%0.4627%0.27SS..EExtended strand (participates in β ladder)trans-76.254.5172.7-71.94.5000110.8M481 P482 V483N319-M481 PolarHBondContact ND2-O 3.19Å; N319-P482 CarbonylContact O-C 3.55Å; N319-P482 VanDerWaalsContact O-CA 3.23Å; N319-P482 WeakPolarHBondContact O-CA 3.48Å; N319-V483 HydrophobicContact CB-CG2 3.95Å; N319-V483 PolarHBondContact O-N 3.1Å
320A89.8Confident86.3Confident0 Ų051.4 Ų51.40%026%0.261CS..EExtended strand (participates in β ladder)trans-143.8156.7173.800000108.2P310 V311 I318 V516P310-A320 CarbonylContact C-O 3.54Å; P310-A320 WeakPolarHBondContact CA-O 3.48Å; V311-A320 HydrophobicContact CG2-CB 4.4Å; V311-A320 PolarHBondContact N-O 2.03Å; I318-A320 HydrophobicContact CG2-CB 3.95Å; I318-A320 PolarHBondContact O-N 3.32Å; A320-V516 HydrophobicContact CB-CG1 4.05Å
321T93.5Very high86.6Confident0 Ų050.9 Ų50.90%026%0.262CS..EExtended strand (participates in β ladder)trans-124.7161.7-177.460.20000111.3D273 P274 N287 G288 K289 E309 F480D273-T321 CarbonylContact C-O 3.57Å; D273-T321 WeakPolarHBondContact CA-O 3.36Å; D273-T321 WeakPolarHBondContact CB-O 3.4Å; P274-T321 WeakPolarHBondContact CD-O 3.25Å; P274-T321 WeakPolarHBondContact CD-OG1 3.3Å; N287-T321 WeakPolarHBondContact CA-OG1 3.29Å; N287-T321 PolarHBondContact OD1-N 2.76Å; N287-T321 PolarHBondContact OD1-O 2.76Å; N287-T321 PolarHBondContact OD1-OG1 3.14Å; G288-T321 PolarHBondContact O-OG1 2.83Å; K289-T321 HydrophobicContact CB-CG2 4.21Å; E309-T321 CarbonylContact O-C 3.5Å; E309-T321 WeakPolarHBondContact O-CA 3.47Å; E309-T321 WeakPolarHBondContact O-CB 3.49Å; T321-F480 HydrophobicContact CG2-CD1 4.3Å; T321-F480 HydrophobicContact CG2-CE1 3.47Å; T321-F480 VanDerWaalsContact CG2-CE1 3.47Å; T321-F480 HydrophobicContact CG2-CE2 4.39Å; T321-F480 HydrophobicContact CG2-CZ 3.51Å
322K93.6Very high87Confident41 Ų4155.1 Ų55.118%0.17829%0.292CS..EExtended strand (participates in β ladder)trans-137.7154.1171.464.6179.3-177.4177.20110.8T308 E309 V311 T324 E395T308-K322 CarbonylContact C-O 3.58Å; T308-K322 WeakPolarHBondContact CA-O 3.32Å; E309-K322 PolarHBondContact N-O 3.09Å; E309-K322 PolarHBondContact O-N 2.76Å; V311-K322 HydrophobicContact CG2-CB 4.19Å; V311-K322 HydrophobicContact CG2-CD 4.36Å; V311-K322 HydrophobicContact CG2-CG 4.23Å; K322-T324 HydrophobicContact CG-CG2 4.28Å; K322-T324 PolarHBondContact O-N 2.84Å; K322-E395 PolarHBondContact NZ-O 2.9Å
323L96.7Very high87.9Confident3 Ų347.4 Ų47.42%0.01626%0.259CS..EExtended strand (participates in β ladder)trans-66.8128.1174.5-162.271.6000110V270 R307 T308 V326 M397 T399V270-L323 HydrophobicContact CG1-CD2 4.47Å; R307-L323 WeakPolarHBondContact O-CA 3.41Å; R307-L323 WeakPolarHBondContact O-CD1 3.32Å; T308-L323 HydrophobicContact CG2-CD1 4.07Å; L323-V326 HydrophobicContact CD1-CG2 4.43Å; L323-V326 HydrophobicContact CD2-CG2 3.68Å; L323-V326 HydrophobicContact CG-CG2 4.17Å; L323-M397 HydrophobicContact CB-CB 4.4Å; L323-M397 HydrophobicContact CB-CE 4.12Å; L323-M397 HydrophobicContact CD2-CE 3.7Å; L323-M397 HydrophobicContact CG-CE 3.49Å; L323-M397 VanDerWaalsContact CG-CE 3.49Å; L323-T399 VanDerWaalsContact CD2-OG1 3.31Å; L323-T399 WeakPolarHBondContact CD2-OG1 3.43Å
324T96.5Very high89.3Confident15 Ų1544.6 Ų44.69%0.09224%0.244CC..EExtended strand (participates in β ladder)trans-123-23-178.162.20000114R307 E309 K322 R339 L340 M397R307-T324 PolarHBondContact O-N 3Å; R307-T324 PolarHBondContact O-OG1 2.49Å; E309-T324 HydrophobicContact CB-CG2 3.76Å; E309-T324 HydrophobicContact CG-CG2 3.53Å; E309-T324 WeakPolarHBondContact CG-OG1 3.4Å; K322-T324 HydrophobicContact CG-CG2 4.28Å; K322-T324 PolarHBondContact O-N 2.84Å; T324-R339 CarbonylContact O-C 3.56Å; T324-R339 VanDerWaalsContact O-CA 3.26Å; T324-R339 WeakPolarHBondContact O-CA 3.22Å; T324-R339 WeakPolarHBondContact O-CB 3.25Å; T324-L340 HydrophobicContact CG2-CD1 4.22Å; T324-L340 PolarHBondContact O-N 2.68Å; T324-M397 VanDerWaalsContact C-CE 3.5Å
325A98Very high91.2Very high0 Ų041.1 Ų41.10%022%0.216CC..EExtended strand (participates in β ladder)trans-146.2150.2171.800000111.5G306 R307 V338 R339 F459G306-A325 CarbonylContact C-O 3.53Å; G306-A325 WeakPolarHBondContact CA-O 3.35Å; R307-A325 HydrophobicContact CB-CB 3.97Å; R307-A325 PolarHBondContact N-O 3.11Å; R307-A325 PolarHBondContact O-N 3.1Å; A325-V338 CarbonylContact C-O 3.6Å; A325-V338 VanDerWaalsContact CA-O 3.23Å; A325-V338 WeakPolarHBondContact CA-O 3.35Å; A325-R339 HydrophobicContact CB-CB 3.7Å; A325-F459 HydrophobicContact CB-CD1 4.07Å; A325-F459 HydrophobicContact CB-CE1 3.83Å
326V98.8Very high93Very high0 Ų031.5 Ų31.50%017%0.171CC..EExtended strand (participates in β ladder)trans-131128.8168.8-175.70000108.4L294 V304 Q305 L323 M328 E337 V338 V390 M397 T399L294-V326 HydrophobicContact CD1-CG1 4.49Å; V304-V326 HydrophobicContact CG1-CG1 3.82Å; Q305-V326 CarbonylContact O-C 3.58Å; Q305-V326 VanDerWaalsContact O-CA 3.26Å; Q305-V326 WeakPolarHBondContact O-CA 3.36Å; Q305-V326 WeakPolarHBondContact O-CG1 3.47Å; L323-V326 HydrophobicContact CD1-CG2 4.43Å; L323-V326 HydrophobicContact CD2-CG2 3.68Å; L323-V326 HydrophobicContact CG-CG2 4.17Å; V326-M328 HydrophobicContact CB-CE 4.11Å; V326-M328 HydrophobicContact CG1-CE 3.73Å; V326-M328 VanDerWaalsContact O-CE 3.29Å; V326-M328 WeakPolarHBondContact O-CE 3.19Å; V326-E337 CarbonylContact O-C 3.47Å; V326-E337 WeakPolarHBondContact O-CA 3.19Å; V326-V338 PolarHBondContact N-O 2.92Å; V326-V338 PolarHBondContact O-N 3.45Å; V326-V390 HydrophobicContact CB-CG2 4.41Å; V326-M397 HydrophobicContact CG2-CE 3.76Å; V326-T399 HydrophobicContact CG1-CG2 4.12Å; V326-T399 HydrophobicContact CG2-CG2 4.14Å; V326-T399 VanDerWaalsContact CG2-OG1 3.3Å; V326-T399 WeakPolarHBondContact CG2-OG1 3.44Å
327A98.8Very high94.5Very high0 Ų024 Ų240%014%0.138CC..EExtended strand (participates in β ladder)trans-120.7138.2176.800000110.2V304 Q305 I336 E337 L458 F459V304-A327 WeakPolarHBondContact CA-O 3.02Å; Q305-A327 PolarHBondContact N-O 2.91Å; Q305-A327 PolarHBondContact O-N 2.8Å; A327-I336 CarbonylContact C-O 3.4Å; A327-I336 WeakPolarHBondContact CA-O 3.38Å; A327-E337 HydrophobicContact CB-CB 4.21Å; A327-E337 HydrophobicContact CB-CG 4.41Å; A327-L458 HydrophobicContact CB-CB 3.6Å; A327-F459 HydrophobicContact CB-CD1 3.63Å; A327-F459 HydrophobicContact CB-CE1 3.63Å; A327-F459 HydrophobicContact CB-CG 4.1Å; A327-F459 HydrophobicContact CB-CZ 4.1Å
328M98.8Very high95.8Very high0 Ų020.2 Ų20.20%012%0.115CC..EExtended strand (participates in β ladder)trans-144.7150-172.563-136.883.300113T303 V304 V326 I336 V338 V380 F382 V388T303-M328 VanDerWaalsContact O-CA 3.26Å; T303-M328 WeakPolarHBondContact O-CA 3.27Å; V304-M328 HydrophobicContact CG1-CB 4.37Å; V304-M328 HydrophobicContact CG2-CB 4.14Å; V326-M328 HydrophobicContact CB-CE 4.11Å; V326-M328 HydrophobicContact CG1-CE 3.73Å; V326-M328 VanDerWaalsContact O-CE 3.29Å; V326-M328 WeakPolarHBondContact O-CE 3.19Å; M328-I336 WeakPolarHBondContact CE-O 3.25Å; M328-I336 HydrophobicContact CG-CB 4.2Å; M328-I336 PolarHBondContact N-O 2.96Å; M328-I336 PolarHBondContact O-N 3.29Å; M328-V338 HydrophobicContact CE-CG2 3.81Å; M328-V380 HydrophobicContact CG-CB 4.44Å; M328-V380 HydrophobicContact CG-CG1 4.05Å; M328-V380 HydrophobicContact SD-CB 3.73Å; M328-V380 HydrophobicContact SD-CG1 4.01Å; M328-V380 HydrophobicContact SD-CG2 3.65Å; M328-F382 HydrophobicContact CB-CE2 4.23Å; M328-F382 HydrophobicContact CB-CZ 4.12Å; M328-F382 HydrophobicContact CG-CE2 4.02Å; M328-F382 HydrophobicContact CG-CZ 3.8Å; M328-V388 HydrophobicContact CE-CG1 4.47Å; M328-V388 HydrophobicContact SD-CB 3.66Å; M328-V388 HydrophobicContact SD-CG1 3.66Å; M328-V388 HydrophobicContact SD-CG2 4Å
329K98.6Very high96.6Very high65 Ų6520.8 Ų20.828%0.28312%0.116SC..EExtended strand (participates in β ladder)trans-156.7146.7179.7-164.8-165.5-175.5-163.30111.3T303 G331 S333 I335 L458T303-K329 PolarHBondContact N-O 3.12Å; T303-K329 PolarHBondContact O-N 2.86Å; K329-G331 WeakPolarHBondContact CE-O 3.26Å; K329-G331 PolarHBondContact NZ-O 3.26Å; K329-G331 VanDerWaalsContact NZ-O 3.09Å; K329-S333 WeakPolarHBondContact CE-O 3.43Å; K329-S333 WeakPolarHBondContact CG-OG 3.43Å; K329-I335 HydrophobicContact CB-CG1 4.27Å; K329-I335 HydrophobicContact CD-CD1 4.42Å; K329-I335 HydrophobicContact CD-CG1 3.79Å; K329-I335 HydrophobicContact CG-CG1 3.98Å; K329-L458 HydrophobicContact CB-CD1 3.94Å; K329-L458 HydrophobicContact CB-CD2 4.31Å; K329-L458 HydrophobicContact CD-CD2 4.42Å
330E98.2Very high97Very high21 Ų2118.6 Ų18.610%0.09810%0.104CC..EExtended strand (participates in β ladder)trans-125.2120.2167.1-178.6167.799.400111.3Q301 L302 S332 S333 F382 P383 S384Q301-E330 WeakPolarHBondContact O-CA 3.26Å; L302-E330 HydrophobicContact CD1-CB 4.21Å; E330-S332 PolarHBondContact O-N 3.06Å; E330-S332 VanDerWaalsContact O-N 3.1Å; E330-S333 PolarHBondContact N-OG 3.05Å; E330-S333 WeakPolarHBondContact O-CB 3.13Å; E330-S333 PolarHBondContact O-N 3.45Å; E330-S333 PolarHBondContact O-OG 2.78Å; E330-F382 HydrophobicContact CB-CB 4.05Å; E330-F382 HydrophobicContact CB-CD1 3.38Å; E330-F382 HydrophobicContact CB-CE1 3.87Å; E330-F382 HydrophobicContact CB-CG 3.75Å; E330-F382 HydrophobicContact CG-CB 4.48Å; E330-P383 WeakPolarHBondContact OE1-CD 3.19Å; E330-S384 WeakPolarHBondContact OE1-CB 3.49Å; E330-S384 PolarHBondContact OE1-N 2.9Å; E330-S384 PolarHBondContact OE1-OG 2.83Å; E330-S384 WeakPolarHBondContact OE2-CB 3.5Å; E330-S384 PolarHBondContact OE2-OG 3.42Å
331G96.7Very high96.8Very high21 Ų2121 Ų2122%0.21612%0.117CC..THydrogen-bonded Turntrans53.3-116.9176.700000113.2Q301 K329Q301-G331 PolarHBondContact O-N 2.9Å; K329-G331 WeakPolarHBondContact CE-O 3.26Å; K329-G331 PolarHBondContact NZ-O 3.26Å; K329-G331 VanDerWaalsContact NZ-O 3.09Å
332S96Very high95.9Very high95 Ų9532.7 Ų32.766%0.66416%0.161SC*.THydrogen-bonded Turntrans-97.818177.866.80000113.9E330 Q366E330-S332 PolarHBondContact O-N 3.06Å; E330-S332 VanDerWaalsContact O-N 3.1Å; S332-Q366 PolarHBondContact O-NE2 2.96Å
333S97.7Very high95Very high7 Ų741.2 Ų41.25%0.04919%0.192CC..SBendtrans-63.1161.3174.879.20000111.4K329 E330 Q366 G367K329-S333 WeakPolarHBondContact CE-O 3.43Å; K329-S333 WeakPolarHBondContact CG-OG 3.43Å; E330-S333 PolarHBondContact N-OG 3.05Å; E330-S333 WeakPolarHBondContact O-CB 3.13Å; E330-S333 PolarHBondContact O-N 3.45Å; E330-S333 PolarHBondContact O-OG 2.78Å; S333-Q366 CarbonylContact C-O 3.59Å; S333-Q366 WeakPolarHBondContact CA-O 3.25Å; S333-Q366 WeakPolarHBondContact CB-O 3.33Å; S333-G367 WeakPolarHBondContact CB-O 3.21Å
334D98.3Very high94.3Very high7 Ų746.8 Ų46.84%0.03722%0.222CC..PPolyproline II helixtrans-56.9147.5159.6-71.7-38.5000110.2I336 R350 N351 Q366 V368D334-I336 HydrophobicContact CB-CD1 4.5Å; D334-R350 HydrophobicContact CB-CG 4.07Å; D334-R350 VanDerWaalsContact CG-NE 3.33Å; D334-R350 IonicContact OD1-NE 3.41Å; D334-R350 IonicContact OD1-NH2 3.87Å; D334-R350 IonicContact OD2-CZ 3.4Å; D334-R350 IonicContact OD2-NE 2.8Å; D334-R350 PolarHBondContact OD2-NE 2.92Å; D334-R350 IonicContact OD2-NH2 2.67Å; D334-R350 PolarHBondContact OD2-NH2 2.72Å; D334-N351 PolarHBondContact OD1-ND2 3.13Å; D334-Q366 PolarHBondContact N-O 2.91Å; D334-Q366 WeakPolarHBondContact OD2-CB 3.42Å; D334-Q366 PolarHBondContact OD2-N 2.81Å; D334-Q366 VanDerWaalsContact OD2-N 3.11Å; D334-V368 HydrophobicContact CB-CG1 4.1Å
335I98.8Very high94.1Very high41 Ų4146.3 Ų46.321%0.2122%0.219CC..PPolyproline II helixtrans-83.1126.5171.5-62.8170.1000107.8K329 R350 N351 L458K329-I335 HydrophobicContact CB-CG1 4.27Å; K329-I335 HydrophobicContact CD-CD1 4.42Å; K329-I335 HydrophobicContact CD-CG1 3.79Å; K329-I335 HydrophobicContact CG-CG1 3.98Å; I335-R350 WeakPolarHBondContact O-CA 3.21Å; I335-N351 PolarHBondContact N-OD1 3.45Å; I335-N351 PolarHBondContact O-N 3.3Å; I335-L458 HydrophobicContact CD1-CD2 3.96Å; I335-L458 HydrophobicContact CG1-CD2 4.27Å; I335-L458 HydrophobicContact CG2-CB 4.05Å; I335-L458 WeakPolarHBondContact CG2-O 3.4Å
336I98.9Very high94Very high0 Ų047.3 Ų47.30%023%0.225CC..EExtended strand (participates in β ladder)trans-108.7122.5174.4-53.2-57.5000108.8A327 M328 D334 V338 L348 L349 R350 L365 V368 V370 V380A327-I336 CarbonylContact C-O 3.4Å; A327-I336 WeakPolarHBondContact CA-O 3.38Å; M328-I336 WeakPolarHBondContact CE-O 3.25Å; M328-I336 HydrophobicContact CG-CB 4.2Å; M328-I336 PolarHBondContact N-O 2.96Å; M328-I336 PolarHBondContact O-N 3.29Å; D334-I336 HydrophobicContact CB-CD1 4.5Å; I336-V338 HydrophobicContact CG2-CG2 4.39Å; I336-L348 HydrophobicContact CG2-CD1 4.01Å; I336-L348 HydrophobicContact CG2-CD2 4.19Å; I336-L348 HydrophobicContact CG2-CG 4.12Å; I336-L349 WeakPolarHBondContact CA-O 3.4Å; I336-R350 HydrophobicContact CD1-CB 4.37Å; I336-R350 HydrophobicContact CD1-CG 4.42Å; I336-L365 HydrophobicContact CD1-CD1 3.72Å; I336-V368 HydrophobicContact CD1-CG1 4.07Å; I336-V368 HydrophobicContact CG1-CG1 3.99Å; I336-V368 HydrophobicContact CG1-CG2 4.08Å; I336-V370 HydrophobicContact CD1-CG2 4.07Å; I336-V370 HydrophobicContact CG1-CG2 4.12Å; I336-V380 HydrophobicContact CB-CG1 4.33Å; I336-V380 HydrophobicContact CB-CG2 4.45Å; I336-V380 HydrophobicContact CG1-CG1 4.17Å; I336-V380 HydrophobicContact CG2-CG2 3.82Å
337E98.8Very high93.9Very high2 Ų249.4 Ų49.41%0.00924%0.235CC..EExtended strand (participates in β ladder)trans-112.6131.7169.9175.9-177.6170.200109.2R307 V326 A327 L348 L349 F459 T460R307-E337 IonicContact NH1-OE1 3.67Å; V326-E337 CarbonylContact O-C 3.47Å; V326-E337 WeakPolarHBondContact O-CA 3.19Å; A327-E337 HydrophobicContact CB-CB 4.21Å; A327-E337 HydrophobicContact CB-CG 4.41Å; E337-L348 CarbonylContact O-C 3.59Å; E337-L348 WeakPolarHBondContact O-CA 3.13Å; E337-L349 HydrophobicContact CB-CB 4.27Å; E337-L349 HydrophobicContact CG-CD1 4.5Å; E337-L349 PolarHBondContact N-O 2.75Å; E337-L349 PolarHBondContact O-N 2.63Å; E337-F459 HydrophobicContact CG-CD1 4.29Å; E337-T460 WeakPolarHBondContact OE2-CB 3.41Å; E337-T460 PolarHBondContact OE2-N 3.13Å; E337-T460 PolarHBondContact OE2-OG1 2.68Å
338V98.6Very high93.8Very high0 Ų049.8 Ų49.80%024%0.237CC..EExtended strand (participates in β ladder)trans-116.9122.5173.6-164.30000107.5A325 V326 M328 I336 L346 E347 L348 V378 V390A325-V338 CarbonylContact C-O 3.6Å; A325-V338 VanDerWaalsContact CA-O 3.23Å; A325-V338 WeakPolarHBondContact CA-O 3.35Å; V326-V338 PolarHBondContact N-O 2.92Å; V326-V338 PolarHBondContact O-N 3.45Å; M328-V338 HydrophobicContact CE-CG2 3.81Å; I336-V338 HydrophobicContact CG2-CG2 4.39Å; V338-L346 HydrophobicContact CG1-CB 3.98Å; V338-L346 HydrophobicContact CG1-CD1 4.07Å; V338-L346 HydrophobicContact CG1-CD2 4.21Å; V338-L346 HydrophobicContact CG1-CG 4.31Å; V338-E347 WeakPolarHBondContact CA-O 3.3Å; V338-L348 HydrophobicContact CB-CD1 4.31Å; V338-L348 HydrophobicContact CG1-CD1 4.22Å; V338-L348 HydrophobicContact CG2-CD1 3.58Å; V338-V378 HydrophobicContact CG1-CB 4.2Å; V338-V378 HydrophobicContact CG1-CG1 4.49Å; V338-V378 HydrophobicContact CG1-CG2 4.02Å; V338-V378 HydrophobicContact CG2-CB 4.48Å; V338-V378 HydrophobicContact CG2-CG1 3.94Å; V338-V390 HydrophobicContact CB-CB 4.36Å; V338-V390 HydrophobicContact CB-CG1 4.24Å; V338-V390 HydrophobicContact CB-CG2 4.12Å; V338-V390 HydrophobicContact CG1-CB 4.07Å; V338-V390 HydrophobicContact CG1-CG1 3.84Å; V338-V390 HydrophobicContact CG1-CG2 4.38Å; V338-V390 HydrophobicContact CG2-CB 4.49Å; V338-V390 HydrophobicContact CG2-CG2 3.99Å
339R97.2Very high93.8Very high33 Ų3349.9 Ų49.913%0.12524%0.237CC..EExtended strand (participates in β ladder)trans-134.5158.1-179.167.6-174.1-173.3-174.2-0.7112.6T324 A325 D341 L346 E347 L349 D462T324-R339 CarbonylContact O-C 3.56Å; T324-R339 VanDerWaalsContact O-CA 3.26Å; T324-R339 WeakPolarHBondContact O-CA 3.22Å; T324-R339 WeakPolarHBondContact O-CB 3.25Å; A325-R339 HydrophobicContact CB-CB 3.7Å; R339-D341 PolarHBondContact O-N 2.8Å; R339-L346 CarbonylContact O-C 3.55Å; R339-L346 WeakPolarHBondContact O-CA 3.42Å; R339-E347 HydrophobicContact CG-CB 4.1Å; R339-E347 IonicContact CZ-OE2 3.31Å; R339-E347 PolarHBondContact N-O 3.11Å; R339-E347 IonicContact NE-OE2 2.83Å; R339-E347 PolarHBondContact NE-OE2 3.04Å; R339-E347 IonicContact NH2-OE1 3.63Å; R339-E347 IonicContact NH2-OE2 3.25Å; R339-E347 PolarHBondContact NH2-OE2 3.09Å; R339-E347 PolarHBondContact O-N 2.92Å; R339-L349 HydrophobicContact CG-CD1 4.02Å; R339-D462 IonicContact CZ-OD1 3.96Å; R339-D462 IonicContact CZ-OD2 2.68Å; R339-D462 VanDerWaalsContact NH1-CG 3.33Å; R339-D462 IonicContact NH1-OD1 2.71Å; R339-D462 PolarHBondContact NH1-OD1 3.49Å; R339-D462 IonicContact NH1-OD2 3.29Å; R339-D462 PolarHBondContact NH1-OD2 3.01Å; R339-D462 VanDerWaalsContact NH1-OD2 3.14Å; R339-D462 IonicContact NH2-OD1 3.12Å; R339-D462 IonicContact NH2-OD2 3.96Å; R339-D462 PolarHBondContact NH2-OD2 3.32Å
340L94.6Very high93.8Very high40 Ų4051.1 Ų51.121%0.20924%0.24CC..EExtended strand (participates in β ladder)trans-64.4123.7176.3-69.1178.2000110.6T324 L346 R392 M397T324-L340 HydrophobicContact CG2-CD1 4.22Å; T324-L340 PolarHBondContact O-N 2.68Å; L340-L346 HydrophobicContact CD2-CD2 4.13Å; L340-R392 HydrophobicContact CD2-CG 4.21Å; L340-M397 HydrophobicContact CD2-CB 4.14Å; L340-M397 HydrophobicContact CD2-SD 4.31Å; L340-M397 HydrophobicContact CG-SD 4.42Å
341D85.1Confident93.8Very high49 Ų4953.4 Ų53.426%0.26225%0.253SS..  trans-85.8150.8173.3179.528.5000111.4R339 R343 N344 G345 E347 R392R339-D341 PolarHBondContact O-N 2.8Å; D341-R343 PolarHBondContact O-N 3.16Å; D341-R343 PolarHBondContact OD1-N 3.36Å; D341-R343 WeakPolarHBondContact OD2-CB 3.45Å; D341-R343 WeakPolarHBondContact OD2-CG 3.27Å; D341-R343 PolarHBondContact OD2-N 2.77Å; D341-N344 PolarHBondContact O-N 3.23Å; D341-G345 PolarHBondContact N-O 2.83Å; D341-E347 HydrophobicContact CB-CB 4.2Å; D341-R392 PolarHBondContact O-NH1 3.42Å; D341-R392 VanDerWaalsContact O-NH1 3.1Å
342R74.5Confident93.8Very high246 Ų24659 Ų5993%0.92827%0.274SS*.THydrogen-bonded Turntrans-62.4-23.2172.9-63.4-175.2-178.5-177.92112.9N344R342-N344 VanDerWaalsContact C-N 3.3Å; R342-N344 PolarHBondContact O-N 2.85Å
343R76Confident93.9Very high221 Ų22161.7 Ų61.783%0.83428%0.275SS*.THydrogen-bonded Turntrans-92.426.4-179.9-49.2-180-178.4-169.61.7114.1D341 G345D341-R343 PolarHBondContact O-N 3.16Å; D341-R343 PolarHBondContact OD1-N 3.36Å; D341-R343 WeakPolarHBondContact OD2-CB 3.45Å; D341-R343 WeakPolarHBondContact OD2-CG 3.27Å; D341-R343 PolarHBondContact OD2-N 2.77Å; R343-G345 VanDerWaalsContact C-N 3.3Å; R343-G345 PolarHBondContact O-N 3.49Å
344N81.8Confident93.7Very high120 Ų12065.5 Ų65.564%0.64230%0.298SS*.SBendtrans66.520.8-178.7-66.4-25.2000116.5D341 R342 R392D341-N344 PolarHBondContact O-N 3.23Å; R342-N344 VanDerWaalsContact C-N 3.3Å; R342-N344 PolarHBondContact O-N 2.85Å; N344-R392 PolarHBondContact O-NE 3.44Å; N344-R392 PolarHBondContact OD1-NH2 3.19Å
345G92.3Very high93.6Very high4 Ų466.8 Ų66.84%0.04131%0.305CS..SBendtrans-115.7-163.6173.400000114.4D341 R343 S375 R392D341-G345 PolarHBondContact N-O 2.83Å; R343-G345 VanDerWaalsContact C-N 3.3Å; R343-G345 PolarHBondContact O-N 3.49Å; G345-S375 CarbonylContact C-O 3.25Å; G345-R392 VanDerWaalsContact N-NH1 3.18Å; G345-R392 PolarHBondContact O-NH1 2.97Å
346L96.2Very high93.3Very high21 Ų2168.6 Ų68.611%0.1132%0.322CS..EExtended strand (participates in β ladder)trans-107.4131.3166.6-63.8174.2000108.5V338 R339 L340 S375 T376 V378 V390 R392 M397V338-L346 HydrophobicContact CG1-CB 3.98Å; V338-L346 HydrophobicContact CG1-CD1 4.07Å; V338-L346 HydrophobicContact CG1-CD2 4.21Å; V338-L346 HydrophobicContact CG1-CG 4.31Å; R339-L346 CarbonylContact O-C 3.55Å; R339-L346 WeakPolarHBondContact O-CA 3.42Å; L340-L346 HydrophobicContact CD2-CD2 4.13Å; L346-S375 WeakPolarHBondContact CB-O 3.3Å; L346-S375 PolarHBondContact N-O 3.08Å; L346-T376 WeakPolarHBondContact CD1-O 3.26Å; L346-V378 HydrophobicContact CB-CG2 4.35Å; L346-V378 HydrophobicContact CD1-CB 4.45Å; L346-V378 HydrophobicContact CD1-CG2 3.98Å; L346-V390 HydrophobicContact CD1-CB 4.43Å; L346-V390 HydrophobicContact CD1-CG1 4.01Å; L346-V390 HydrophobicContact CD2-CG1 4.28Å; L346-R392 HydrophobicContact CD1-CB 4.46Å; L346-R392 HydrophobicContact CD2-CB 4.07Å; L346-R392 HydrophobicContact CG-CB 4.1Å; L346-M397 HydrophobicContact CD2-CG 4.36Å; L346-M397 HydrophobicContact CD2-SD 3.81Å
347E96.3Very high93Very high45 Ų4570.4 Ų70.421%0.2133%0.33CS..EExtended strand (participates in β ladder)trans-94.1133.2167.8-174.5179.6-154.700108.7V338 R339 D341 L349 T354V338-E347 WeakPolarHBondContact CA-O 3.3Å; R339-E347 HydrophobicContact CG-CB 4.1Å; R339-E347 IonicContact CZ-OE2 3.31Å; R339-E347 PolarHBondContact N-O 3.11Å; R339-E347 IonicContact NE-OE2 2.83Å; R339-E347 PolarHBondContact NE-OE2 3.04Å; R339-E347 IonicContact NH2-OE1 3.63Å; R339-E347 IonicContact NH2-OE2 3.25Å; R339-E347 PolarHBondContact NH2-OE2 3.09Å; R339-E347 PolarHBondContact O-N 2.92Å; D341-E347 HydrophobicContact CB-CB 4.2Å; E347-L349 HydrophobicContact CG-CD1 3.98Å; E347-T354 HydrophobicContact CG-CG2 4.02Å; E347-T354 WeakPolarHBondContact OE1-CG2 3.03Å; E347-T354 PolarHBondContact OE1-OG1 2.86Å
348L97.1Very high92.5Very high8 Ų874.5 Ų74.54%0.04236%0.364CS..EExtended strand (participates in β ladder)trans-106.4134.3175.7-154.593.2000110.2I336 E337 V338 T354 L355 F357 V370 V378I336-L348 HydrophobicContact CG2-CD1 4.01Å; I336-L348 HydrophobicContact CG2-CD2 4.19Å; I336-L348 HydrophobicContact CG2-CG 4.12Å; E337-L348 CarbonylContact O-C 3.59Å; E337-L348 WeakPolarHBondContact O-CA 3.13Å; V338-L348 HydrophobicContact CB-CD1 4.31Å; V338-L348 HydrophobicContact CG1-CD1 4.22Å; V338-L348 HydrophobicContact CG2-CD1 3.58Å; L348-T354 CarbonylContact O-C 3.4Å; L348-T354 WeakPolarHBondContact O-CA 2.98Å; L348-L355 HydrophobicContact CD2-CB 4.24Å; L348-L355 HydrophobicContact CD2-CD2 3.83Å; L348-L355 PolarHBondContact O-N 2.79Å; L348-F357 HydrophobicContact CB-CE2 4.47Å; L348-F357 HydrophobicContact CD2-CE2 3.53Å; L348-F357 HydrophobicContact CD2-CZ 4.04Å; L348-V370 HydrophobicContact CD1-CG1 4.42Å; L348-V370 HydrophobicContact CD2-CG1 3.73Å; L348-V378 HydrophobicContact CD1-CB 4.25Å; L348-V378 HydrophobicContact CD1-CG1 3.39Å; L348-V378 HydrophobicContact CD1-CG2 3.91Å
349L98.2Very high91.9Very high1 Ų183.1 Ų83.11%0.00540%0.404CS..EExtended strand (participates in β ladder)trans-122.2137.1173.7-61.984.4000109.9I336 E337 R339 E347 Q353 T460I336-L349 WeakPolarHBondContact CA-O 3.4Å; E337-L349 HydrophobicContact CB-CB 4.27Å; E337-L349 HydrophobicContact CG-CD1 4.5Å; E337-L349 PolarHBondContact N-O 2.75Å; E337-L349 PolarHBondContact O-N 2.63Å; R339-L349 HydrophobicContact CG-CD1 4.02Å; E347-L349 HydrophobicContact CG-CD1 3.98Å; L349-Q353 CarbonylContact C-O 3.59Å; L349-Q353 VanDerWaalsContact CA-O 3.22Å; L349-Q353 WeakPolarHBondContact CA-O 3.37Å; L349-T460 HydrophobicContact CD2-CG2 4.06Å
350R98.1Very high91.6Very high91 Ų9185.7 Ų85.734%0.34342%0.418SS..EExtended strand (participates in β ladder)trans-111.2118170.4176.8-163.8177.2-164.7-1.7107.9D334 I335 I336 Q352 Q353 L355 L365D334-R350 HydrophobicContact CB-CG 4.07Å; D334-R350 VanDerWaalsContact CG-NE 3.33Å; D334-R350 IonicContact OD1-NE 3.41Å; D334-R350 IonicContact OD1-NH2 3.87Å; D334-R350 IonicContact OD2-CZ 3.4Å; D334-R350 IonicContact OD2-NE 2.8Å; D334-R350 PolarHBondContact OD2-NE 2.92Å; D334-R350 IonicContact OD2-NH2 2.67Å; D334-R350 PolarHBondContact OD2-NH2 2.72Å; I335-R350 WeakPolarHBondContact O-CA 3.21Å; I336-R350 HydrophobicContact CD1-CB 4.37Å; I336-R350 HydrophobicContact CD1-CG 4.42Å; R350-Q352 VanDerWaalsContact C-N 3.27Å; R350-Q352 PolarHBondContact O-N 2.84Å; R350-Q353 PolarHBondContact N-O 2.88Å; R350-Q353 PolarHBondContact O-N 2.72Å; R350-L355 HydrophobicContact CB-CB 4.49Å; R350-L355 HydrophobicContact CB-CD2 4.4Å; R350-L365 HydrophobicContact CG-CD1 4.26Å
351N97.9Very high91.5Very high70 Ų7086.9 Ų86.937%0.37443%0.427SS..THydrogen-bonded Turntrans45.851.2-179.5-58.4-32.8000112.5D334 I335 Q353D334-N351 PolarHBondContact OD1-ND2 3.13Å; I335-N351 PolarHBondContact N-OD1 3.45Å; I335-N351 PolarHBondContact O-N 3.3Å; N351-Q353 VanDerWaalsContact C-N 3.26Å; N351-Q353 PolarHBondContact O-N 3.06Å
352Q97.1Very high91.8Very high139 Ų13989.2 Ų89.265%0.6543%0.432SS*.THydrogen-bonded Turntrans71.75.1179.6-49.5168.83000116.3R350 T460R350-Q352 VanDerWaalsContact C-N 3.27Å; R350-Q352 PolarHBondContact O-N 2.84Å; Q352-T460 WeakPolarHBondContact CA-OG1 3.43Å; Q352-T460 HydrophobicContact CB-CG2 3.69Å; Q352-T460 HydrophobicContact CG-CG2 3.98Å
353Q97.4Very high92.7Very high150 Ų15078.4 Ų78.470%0.70139%0.392SS*.EExtended strand (participates in β ladder)trans-113.2133.9176.8-62.5-175.9-200111.2L349 R350 N351 L355L349-Q353 CarbonylContact C-O 3.59Å; L349-Q353 VanDerWaalsContact CA-O 3.22Å; L349-Q353 WeakPolarHBondContact CA-O 3.37Å; R350-Q353 PolarHBondContact N-O 2.88Å; R350-Q353 PolarHBondContact O-N 2.72Å; N351-Q353 VanDerWaalsContact C-N 3.26Å; N351-Q353 PolarHBondContact O-N 3.06Å; Q353-L355 PolarHBondContact O-N 3.04Å
354T95.3Very high93.4Very high87 Ų8770.8 Ų70.853%0.53437%0.368SS..EExtended strand (participates in β ladder)trans-59.1131.9177.3-53.10000111.3E347 L348E347-T354 HydrophobicContact CG-CG2 4.02Å; E347-T354 WeakPolarHBondContact OE1-CG2 3.03Å; E347-T354 PolarHBondContact OE1-OG1 2.86Å; L348-T354 CarbonylContact O-C 3.4Å; L348-T354 WeakPolarHBondContact O-CA 2.98Å
355L95.1Very high93.9Very high34 Ų3466.2 Ų66.218%0.17834%0.343CS..  trans-110.2121.6178.1-168.366.3000110.1L348 R350 Q353 F357 M363 L365L348-L355 HydrophobicContact CD2-CB 4.24Å; L348-L355 HydrophobicContact CD2-CD2 3.83Å; L348-L355 PolarHBondContact O-N 2.79Å; R350-L355 HydrophobicContact CB-CB 4.49Å; R350-L355 HydrophobicContact CB-CD2 4.4Å; Q353-L355 PolarHBondContact O-N 3.04Å; L355-F357 HydrophobicContact CD2-CE2 3.88Å; L355-F357 HydrophobicContact CD2-CZ 4.14Å; L355-F357 HydrophobicContact CG-CE2 4.04Å; L355-M363 HydrophobicContact CD1-CE 4.2Å; L355-M363 HydrophobicContact CD1-SD 3.81Å; L355-M363 HydrophobicContact CD2-CE 4.31Å; L355-M363 HydrophobicContact CD2-SD 3.74Å; L355-M363 HydrophobicContact CG-CE 3.95Å; L355-M363 HydrophobicContact CG-SD 3.86Å; L355-L365 HydrophobicContact CD2-CD1 3.85Å; L355-L365 HydrophobicContact CD2-CD2 4.49Å
356S92.8Very high94Very high80 Ų8071.5 Ų71.556%0.55937%0.367SS*.  trans-95.7128.5-175.6-179.30000112.6A358 M363S356-A358 WeakPolarHBondContact OG-CB 3.28Å; S356-A358 PolarHBondContact OG-N 3.41Å; S356-M363 WeakPolarHBondContact O-CE 3.41Å
357F92.9Very high93.8Very high37 Ų3772.1 Ų72.116%0.16238%0.378CS..  trans-102.428.8173.3-74-101.5000112.1L348 L355 E359 Q360 M363 V370L348-F357 HydrophobicContact CB-CE2 4.47Å; L348-F357 HydrophobicContact CD2-CE2 3.53Å; L348-F357 HydrophobicContact CD2-CZ 4.04Å; L355-F357 HydrophobicContact CD2-CE2 3.88Å; L355-F357 HydrophobicContact CD2-CZ 4.14Å; L355-F357 HydrophobicContact CG-CE2 4.04Å; F357-E359 VanDerWaalsContact C-N 3.31Å; F357-E359 PolarHBondContact O-N 2.97Å; F357-Q360 CarbonylContact C-O 3.54Å; F357-Q360 WeakPolarHBondContact CA-O 3.21Å; F357-Q360 WeakPolarHBondContact CB-O 3.18Å; F357-Q360 WeakPolarHBondContact CD1-O 3.19Å; F357-Q360 VanDerWaalsContact O-O 3.06Å; F357-M363 HydrophobicContact CD1-CE 4.01Å; F357-M363 HydrophobicContact CD2-CE 4.01Å; F357-M363 HydrophobicContact CE1-CE 3.95Å; F357-M363 HydrophobicContact CE1-CG 3.91Å; F357-M363 HydrophobicContact CE2-CE 3.9Å; F357-M363 HydrophobicContact CG-CE 4.05Å; F357-M363 HydrophobicContact CZ-CE 3.88Å; F357-M363 HydrophobicContact CZ-CG 4.07Å; F357-M363 HydrophobicContact CZ-SD 4.26Å; F357-V370 HydrophobicContact CE1-CG1 4.45Å; F357-V370 HydrophobicContact CE2-CG1 4.45Å; F357-V370 HydrophobicContact CZ-CB 4.1Å; F357-V370 HydrophobicContact CZ-CG1 3.72Å
358A88.4Confident93.8Very high88 Ų8870 Ų7073%0.72737%0.368SS*.SBendtrans-69.2-28.5-179.200000113.3S356S356-A358 WeakPolarHBondContact OG-CB 3.28Å; S356-A358 PolarHBondContact OG-N 3.41Å
359E86.4Confident93.8Very high182 Ų18269.7 Ų69.785%0.8537%0.367SS*.SBendtrans-107.3-22-174.8-63.6-179.7-175.600113.3F357F357-E359 VanDerWaalsContact C-N 3.31Å; F357-E359 PolarHBondContact O-N 2.97Å
360Q90.2Very high93.8Very high87 Ų8769.6 Ų69.641%0.40737%0.366SS..  trans-142.5155-177.659.3-121.81000111.1F357 M363F357-Q360 CarbonylContact C-O 3.54Å; F357-Q360 WeakPolarHBondContact CA-O 3.21Å; F357-Q360 WeakPolarHBondContact CB-O 3.18Å; F357-Q360 WeakPolarHBondContact CD1-O 3.19Å; F357-Q360 VanDerWaalsContact O-O 3.06Å; Q360-M363 HydrophobicContact CG-CE 3.81Å; Q360-M363 HydrophobicContact CG-CG 4.05Å; Q360-M363 PolarHBondContact NE2-SD 3.4Å; Q360-M363 VanDerWaalsContact NE2-SD 3.44Å
361T91.6Very high93.7Very high65 Ų6567.6 Ų67.640%0.39936%0.36SS..SBendtrans-98.1-11.3179.853.70000113.1F371 S372T361-F371 CarbonylContact O-C 3.02Å; T361-F371 WeakPolarHBondContact O-CD2 3.35Å; T361-S372 CarbonylContact O-C 3.46Å; T361-S372 PolarHBondContact O-N 3.46Å
362W92.9Very high93.6Very high97 Ų9764.9 Ų64.937%0.36735%0.347SS..EExtended strand (participates in β ladder)trans-144158.8176.859.1-89.6000111.8W213 F369 V370 F371W213-W362 HydrophobicContact CG-CH2 4.36Å; W362-F369 HydrophobicContact CB-CE1 3.87Å; W362-F369 HydrophobicContact CB-CZ 3.7Å; W362-F369 HydrophobicContact CD2-CE2 4.16Å; W362-F369 AromaticContact CD2-CZ 3.75Å; W362-F369 HydrophobicContact CD2-CZ 3.75Å; W362-F369 HydrophobicContact CE3-CD2 4.46Å; W362-F369 AromaticContact CE3-CE2 3.37Å; W362-F369 HydrophobicContact CE3-CE2 3.37Å; W362-F369 AromaticContact CE3-CZ 3.44Å; W362-F369 HydrophobicContact CE3-CZ 3.44Å; W362-F369 VanDerWaalsContact CE3-CZ 3.44Å; W362-F369 AromaticContact CG-CZ 3.89Å; W362-F369 HydrophobicContact CG-CZ 3.89Å; W362-F369 AromaticContact CZ3-CE2 3.82Å; W362-F369 HydrophobicContact CZ3-CE2 3.82Å; W362-F369 HydrophobicContact CZ3-CZ 4.26Å; W362-V370 CarbonylContact C-O 3.56Å; W362-V370 WeakPolarHBondContact CA-O 3.44Å; W362-F371 HydrophobicContact CB-CD2 4.01Å
363M92.4Very high93.4Very high20 Ų2060.9 Ų60.910%0.09933%0.333CS..EExtended strand (participates in β ladder)trans-146136.8174.4-57.8-170.4-156.800110.7L355 S356 F357 Q360 L365 V370L355-M363 HydrophobicContact CD1-CE 4.2Å; L355-M363 HydrophobicContact CD1-SD 3.81Å; L355-M363 HydrophobicContact CD2-CE 4.31Å; L355-M363 HydrophobicContact CD2-SD 3.74Å; L355-M363 HydrophobicContact CG-CE 3.95Å; L355-M363 HydrophobicContact CG-SD 3.86Å; S356-M363 WeakPolarHBondContact O-CE 3.41Å; F357-M363 HydrophobicContact CD1-CE 4.01Å; F357-M363 HydrophobicContact CD2-CE 4.01Å; F357-M363 HydrophobicContact CE1-CE 3.95Å; F357-M363 HydrophobicContact CE1-CG 3.91Å; F357-M363 HydrophobicContact CE2-CE 3.9Å; F357-M363 HydrophobicContact CG-CE 4.05Å; F357-M363 HydrophobicContact CZ-CE 3.88Å; F357-M363 HydrophobicContact CZ-CG 4.07Å; F357-M363 HydrophobicContact CZ-SD 4.26Å; Q360-M363 HydrophobicContact CG-CE 3.81Å; Q360-M363 HydrophobicContact CG-CG 4.05Å; Q360-M363 PolarHBondContact NE2-SD 3.4Å; Q360-M363 VanDerWaalsContact NE2-SD 3.44Å; M363-L365 HydrophobicContact CB-CD2 4.16Å; M363-L365 HydrophobicContact CB-CG 4.31Å; M363-V370 PolarHBondContact N-O 3.47Å; M363-V370 PolarHBondContact O-N 2.94Å
364D90.5Very high93.2Very high60 Ų6058 Ų5832%0.32132%0.321SS..EExtended strand (participates in β ladder)trans-93.5116165.2-171.419.7000109.3F218 F369F218-D364 WeakPolarHBondContact CZ-OD2 3.43Å; D364-F369 HydrophobicContact CB-CD2 3.96Å; D364-F369 HydrophobicContact CB-CE2 4.42Å
365L93.3Very high93.1Very high24 Ų2457.5 Ų57.513%0.12632%0.321CS..EExtended strand (participates in β ladder)trans-111-175.7-177.2-56.2175.2000109.4I336 R350 L355 M363 G367 V368 V370I336-L365 HydrophobicContact CD1-CD1 3.72Å; R350-L365 HydrophobicContact CG-CD1 4.26Å; L355-L365 HydrophobicContact CD2-CD1 3.85Å; L355-L365 HydrophobicContact CD2-CD2 4.49Å; M363-L365 HydrophobicContact CB-CD2 4.16Å; M363-L365 HydrophobicContact CB-CG 4.31Å; L365-G367 PolarHBondContact O-N 2.88Å; L365-V368 WeakPolarHBondContact CA-O 3.49Å; L365-V368 HydrophobicContact CB-CG1 3.82Å; L365-V368 WeakPolarHBondContact CB-O 3.13Å; L365-V368 HydrophobicContact CD1-CG1 4.34Å; L365-V368 PolarHBondContact N-O 2.82Å; L365-V370 HydrophobicContact CD1-CG2 4.01Å
366Q93.7Very high93.1Very high115 Ų11557.7 Ų57.754%0.53732%0.324SS..THydrogen-bonded Turntrans-66.6108.4179.2-179177.1-3400109.9S332 S333 D334 V368S332-Q366 PolarHBondContact O-NE2 2.96Å; S333-Q366 CarbonylContact C-O 3.59Å; S333-Q366 WeakPolarHBondContact CA-O 3.25Å; S333-Q366 WeakPolarHBondContact CB-O 3.33Å; D334-Q366 PolarHBondContact N-O 2.91Å; D334-Q366 WeakPolarHBondContact OD2-CB 3.42Å; D334-Q366 PolarHBondContact OD2-N 2.81Å; D334-Q366 VanDerWaalsContact OD2-N 3.11Å; Q366-V368 PolarHBondContact O-N 3.48Å
367G93.1Very high93.3Very high34 Ų3455.5 Ų55.535%0.35131%0.306SS..THydrogen-bonded Turntrans64.421.3175.200000114.7S333 L365 P383S333-G367 WeakPolarHBondContact CB-O 3.21Å; L365-G367 PolarHBondContact O-N 2.88Å; G367-P383 WeakPolarHBondContact O-CD 3.45Å
368V96.3Very high93.6Very high0 Ų053.8 Ų53.80%030%0.298CS..EExtended strand (participates in β ladder)trans-158.3134.9179.263.70000110.5D334 I336 L365 Q366 V370 V380 F382D334-V368 HydrophobicContact CB-CG1 4.1Å; I336-V368 HydrophobicContact CD1-CG1 4.07Å; I336-V368 HydrophobicContact CG1-CG1 3.99Å; I336-V368 HydrophobicContact CG1-CG2 4.08Å; L365-V368 WeakPolarHBondContact CA-O 3.49Å; L365-V368 HydrophobicContact CB-CG1 3.82Å; L365-V368 WeakPolarHBondContact CB-O 3.13Å; L365-V368 HydrophobicContact CD1-CG1 4.34Å; L365-V368 PolarHBondContact N-O 2.82Å; Q366-V368 PolarHBondContact O-N 3.48Å; V368-V370 HydrophobicContact CG2-CG2 4.33Å; V368-V380 HydrophobicContact CG2-CG1 3.33Å; V368-F382 HydrophobicContact CB-CD1 4.01Å; V368-F382 HydrophobicContact CB-CE1 3.85Å; V368-F382 HydrophobicContact CG2-CD1 3.81Å; V368-F382 HydrophobicContact CG2-CE1 3.51Å; V368-F382 HydrophobicContact CG2-CZ 4.05Å
369F96.2Very high94Very high2 Ų249.9 Ų49.91%0.00927%0.266CS..EExtended strand (participates in β ladder)trans-104.5136.7173.3-171.6-82.7000109.1I175 W213 W362 D364 F371 M381I175-F369 HydrophobicContact CG2-CB 3.71Å; I175-F369 HydrophobicContact CG2-CD1 3.94Å; I175-F369 HydrophobicContact CG2-CD2 4.06Å; I175-F369 HydrophobicContact CG2-CG 3.65Å; W213-F369 HydrophobicContact CD2-CE2 4.39Å; W213-F369 HydrophobicContact CE3-CD2 4.45Å; W213-F369 AromaticContact CE3-CE2 3.68Å; W213-F369 HydrophobicContact CE3-CE2 3.68Å; W213-F369 HydrophobicContact CE3-CZ 4.04Å; W213-F369 HydrophobicContact CH2-CE2 4.42Å; W213-F369 AromaticContact CH2-CZ 3.94Å; W213-F369 HydrophobicContact CH2-CZ 3.94Å; W213-F369 HydrophobicContact CZ3-CD2 4.47Å; W213-F369 HydrophobicContact CZ3-CE1 4.33Å; W213-F369 AromaticContact CZ3-CE2 3.69Å; W213-F369 HydrophobicContact CZ3-CE2 3.69Å; W213-F369 AromaticContact CZ3-CZ 3.61Å; W213-F369 HydrophobicContact CZ3-CZ 3.61Å; W362-F369 HydrophobicContact CB-CE1 3.87Å; W362-F369 HydrophobicContact CB-CZ 3.7Å; W362-F369 HydrophobicContact CD2-CE2 4.16Å; W362-F369 AromaticContact CD2-CZ 3.75Å; W362-F369 HydrophobicContact CD2-CZ 3.75Å; W362-F369 HydrophobicContact CE3-CD2 4.46Å; W362-F369 AromaticContact CE3-CE2 3.37Å; W362-F369 HydrophobicContact CE3-CE2 3.37Å; W362-F369 AromaticContact CE3-CZ 3.44Å; W362-F369 HydrophobicContact CE3-CZ 3.44Å; W362-F369 VanDerWaalsContact CE3-CZ 3.44Å; W362-F369 AromaticContact CG-CZ 3.89Å; W362-F369 HydrophobicContact CG-CZ 3.89Å; W362-F369 AromaticContact CZ3-CE2 3.82Å; W362-F369 HydrophobicContact CZ3-CE2 3.82Å; W362-F369 HydrophobicContact CZ3-CZ 4.26Å; D364-F369 HydrophobicContact CB-CD2 3.96Å; D364-F369 HydrophobicContact CB-CE2 4.42Å; F369-F371 HydrophobicContact CE1-CB 4.41Å; F369-M381 HydrophobicContact CB-CB 4.32Å; F369-M381 HydrophobicContact CD1-CE 3.48Å; F369-M381 VanDerWaalsContact CD1-CE 3.48Å; F369-M381 HydrophobicContact CD1-SD 3.98Å; F369-M381 HydrophobicContact CE1-CE 4.08Å; F369-M381 PolarHBondContact N-O 2.74Å; F369-M381 PolarHBondContact O-N 3.39Å
370V97.6Very high94.6Very high0 Ų041.2 Ų41.20%023%0.225CC..EExtended strand (participates in β ladder)trans-127.3130-178.2-173.90000110.4I336 L348 F357 W362 M363 L365 V368 V378 T379 V380I336-V370 HydrophobicContact CD1-CG2 4.07Å; I336-V370 HydrophobicContact CG1-CG2 4.12Å; L348-V370 HydrophobicContact CD1-CG1 4.42Å; L348-V370 HydrophobicContact CD2-CG1 3.73Å; F357-V370 HydrophobicContact CE1-CG1 4.45Å; F357-V370 HydrophobicContact CE2-CG1 4.45Å; F357-V370 HydrophobicContact CZ-CB 4.1Å; F357-V370 HydrophobicContact CZ-CG1 3.72Å; W362-V370 CarbonylContact C-O 3.56Å; W362-V370 WeakPolarHBondContact CA-O 3.44Å; M363-V370 PolarHBondContact N-O 3.47Å; M363-V370 PolarHBondContact O-N 2.94Å; L365-V370 HydrophobicContact CD1-CG2 4.01Å; V368-V370 HydrophobicContact CG2-CG2 4.33Å; V370-V378 HydrophobicContact CG1-CG1 4.16Å; V370-T379 WeakPolarHBondContact CA-O 3.49Å; V370-V380 HydrophobicContact CG1-CG2 4.42Å; V370-V380 HydrophobicContact CG2-CG1 4.42Å; V370-V380 HydrophobicContact CG2-CG2 4.5Å
371F96.7Very high95Very high49 Ų4937.2 Ų37.222%0.21521%0.206CC..EExtended strand (participates in β ladder)trans-120.5126.4176.8177-125.8000110.5H149 T361 W362 F369 P373 V378 T379 M381H149-F371 AromaticContact NE2-CD1 3.93Å; H149-F371 AromaticContact NE2-CD2 3.53Å; H149-F371 AromaticContact NE2-CE1 3.97Å; H149-F371 AromaticContact NE2-CE2 3.58Å; H149-F371 AromaticContact NE2-CG 3.71Å; H149-F371 AromaticContact NE2-CZ 3.79Å; T361-F371 CarbonylContact O-C 3.02Å; T361-F371 WeakPolarHBondContact O-CD2 3.35Å; W362-F371 HydrophobicContact CB-CD2 4.01Å; F369-F371 HydrophobicContact CE1-CB 4.41Å; F371-P373 HydrophobicContact CD1-CG 4.32Å; F371-P373 HydrophobicContact CE1-CB 4.18Å; F371-P373 HydrophobicContact CE1-CG 3.64Å; F371-P373 HydrophobicContact CE2-CB 3.89Å; F371-P373 HydrophobicContact CE2-CG 4.17Å; F371-P373 HydrophobicContact CZ-CB 3.56Å; F371-P373 HydrophobicContact CZ-CG 3.56Å; F371-V378 CarbonylContact O-C 3.53Å; F371-V378 WeakPolarHBondContact O-CA 3.48Å; F371-T379 PolarHBondContact N-O 2.77Å; F371-T379 PolarHBondContact O-N 2.8Å; F371-M381 HydrophobicContact CB-CE 3.67Å
372S96.3Very high95.3Very high13 Ų1334.1 Ų34.19%0.09119%0.187CC..EExtended strand (participates in β ladder)trans-14184.4177.7-172.80000109.4T361 I374 N377T361-S372 CarbonylContact O-C 3.46Å; T361-S372 PolarHBondContact O-N 3.46Å; S372-I374 VanDerWaalsContact C-N 3.29Å; S372-I374 PolarHBondContact O-N 2.93Å; S372-I374 PolarHBondContact OG-O 3.25Å; S372-N377 WeakPolarHBondContact CA-O 3.39Å; S372-N377 PolarHBondContact OG-O 2.83Å
373P91.9Very high95.4Very high54 Ų5432.9 Ų32.935%0.35119%0.192SC..EExtended strand (participates in β ladder)trans-72.1-26.2-17827.7-33.6000112.7F371F371-P373 HydrophobicContact CD1-CG 4.32Å; F371-P373 HydrophobicContact CE1-CB 4.18Å; F371-P373 HydrophobicContact CE1-CG 3.64Å; F371-P373 HydrophobicContact CE2-CB 3.89Å; F371-P373 HydrophobicContact CE2-CG 4.17Å; F371-P373 HydrophobicContact CZ-CB 3.56Å; F371-P373 HydrophobicContact CZ-CG 3.56Å
374I93.1Very high95.5Very high89 Ų8933.3 Ų33.346%0.45620%0.197SC..EExtended strand (participates in β ladder)trans-144.4156.5178.259.4174.7000108.7S372 T376 N377S372-I374 VanDerWaalsContact C-N 3.29Å; S372-I374 PolarHBondContact O-N 2.93Å; S372-I374 PolarHBondContact OG-O 3.25Å; I374-T376 WeakPolarHBondContact CD1-OG1 3.29Å; I374-T376 PolarHBondContact O-N 3.09Å; I374-N377 HydrophobicContact CD1-CB 4.49Å; I374-N377 HydrophobicContact CG1-CB 3.93Å; I374-N377 PolarHBondContact O-N 2.83Å; I374-N377 VanDerWaalsContact O-N 3.12Å
375S93.3Very high95.8Very high78 Ų7830.8 Ų30.855%0.54519%0.185SC..THydrogen-bonded Turntrans-63.1-5.3-17560.50000115.6G345 L346G345-S375 CarbonylContact C-O 3.25Å; L346-S375 WeakPolarHBondContact CB-O 3.3Å; L346-S375 PolarHBondContact N-O 3.08Å
376T95.8Very high96.1Very high37 Ų3729.6 Ų29.623%0.22718%0.179CC..THydrogen-bonded Turntrans-110.2-3.6-179.754.70000114L346 I374 R391 R392L346-T376 WeakPolarHBondContact CD1-O 3.26Å; I374-T376 WeakPolarHBondContact CD1-OG1 3.29Å; I374-T376 PolarHBondContact O-N 3.09Å; T376-R391 WeakPolarHBondContact O-CA 3.18Å; T376-R392 HydrophobicContact CG2-CB 4.3Å; T376-R392 PolarHBondContact O-N 2.57Å
377N96.8Very high96.3Very high34 Ų3424.1 Ų24.118%0.18215%0.153CC..EExtended strand (participates in β ladder)trans-130.4119.7-178.5-68.4-2.3000110S372 I374 R391 R393S372-N377 WeakPolarHBondContact CA-O 3.39Å; S372-N377 PolarHBondContact OG-O 2.83Å; I374-N377 HydrophobicContact CD1-CB 4.49Å; I374-N377 HydrophobicContact CG1-CB 3.93Å; I374-N377 PolarHBondContact O-N 2.83Å; I374-N377 VanDerWaalsContact O-N 3.12Å; N377-R391 VanDerWaalsContact OD1-CD 3.26Å; N377-R391 WeakPolarHBondContact OD1-CD 3.34Å; N377-R393 PolarHBondContact OD1-NH1 2.94Å
378V98.4Very high96.6Very high1 Ų122.5 Ų22.51%0.00614%0.137CC..EExtended strand (participates in β ladder)trans-125128.3172.7174.30000109.3V338 L346 L348 V370 F371 V380 V390 R391V338-V378 HydrophobicContact CG1-CB 4.2Å; V338-V378 HydrophobicContact CG1-CG1 4.49Å; V338-V378 HydrophobicContact CG1-CG2 4.02Å; V338-V378 HydrophobicContact CG2-CB 4.48Å; V338-V378 HydrophobicContact CG2-CG1 3.94Å; L346-V378 HydrophobicContact CB-CG2 4.35Å; L346-V378 HydrophobicContact CD1-CB 4.45Å; L346-V378 HydrophobicContact CD1-CG2 3.98Å; L348-V378 HydrophobicContact CD1-CB 4.25Å; L348-V378 HydrophobicContact CD1-CG1 3.39Å; L348-V378 HydrophobicContact CD1-CG2 3.91Å; V370-V378 HydrophobicContact CG1-CG1 4.16Å; F371-V378 CarbonylContact O-C 3.53Å; F371-V378 WeakPolarHBondContact O-CA 3.48Å; V378-V380 HydrophobicContact CG1-CG2 4Å; V378-V390 HydrophobicContact CB-CB 4.44Å; V378-V390 PolarHBondContact N-O 3.46Å; V378-V390 PolarHBondContact O-N 3.19Å; V378-R391 PolarHBondContact O-NH1 2.78Å
379T98.6Very high96.7Very high7 Ų723.7 Ų23.74%0.04314%0.142CC..EExtended strand (participates in β ladder)trans-114.7131.3168.3-560000108.5V370 F371 M381 V388 E389 R391V370-T379 WeakPolarHBondContact CA-O 3.49Å; F371-T379 PolarHBondContact N-O 2.77Å; F371-T379 PolarHBondContact O-N 2.8Å; T379-M381 HydrophobicContact CG2-CE 3.77Å; T379-M381 HydrophobicContact CG2-CG 3.96Å; T379-M381 HydrophobicContact CG2-SD 3.95Å; T379-M381 WeakPolarHBondContact O-CE 2.97Å; T379-V388 CarbonylContact C-O 3.58Å; T379-V388 WeakPolarHBondContact CA-O 3.41Å; T379-E389 HydrophobicContact CG2-CG 4.28Å; T379-R391 PolarHBondContact OG1-NH1 3.4Å; T379-R391 PolarHBondContact OG1-NH2 2.85Å
380V98.7Very high96.8Very high0 Ų023.6 Ų23.60%014%0.142CC..EExtended strand (participates in β ladder)trans-115.9129.3176-175.20000108.1M328 I336 V368 V370 V378 F382 G387 V388M328-V380 HydrophobicContact CG-CB 4.44Å; M328-V380 HydrophobicContact CG-CG1 4.05Å; M328-V380 HydrophobicContact SD-CB 3.73Å; M328-V380 HydrophobicContact SD-CG1 4.01Å; M328-V380 HydrophobicContact SD-CG2 3.65Å; I336-V380 HydrophobicContact CB-CG1 4.33Å; I336-V380 HydrophobicContact CB-CG2 4.45Å; I336-V380 HydrophobicContact CG1-CG1 4.17Å; I336-V380 HydrophobicContact CG2-CG2 3.82Å; V368-V380 HydrophobicContact CG2-CG1 3.33Å; V370-V380 HydrophobicContact CG1-CG2 4.42Å; V370-V380 HydrophobicContact CG2-CG1 4.42Å; V370-V380 HydrophobicContact CG2-CG2 4.5Å; V378-V380 HydrophobicContact CG1-CG2 4Å; V380-F382 HydrophobicContact CG1-CE1 4.48Å; V380-F382 HydrophobicContact CG1-CE2 3.94Å; V380-F382 HydrophobicContact CG1-CZ 3.87Å; V380-G387 CarbonylContact O-C 3.6Å; V380-G387 WeakPolarHBondContact O-CA 3.25Å; V380-V388 HydrophobicContact CB-CB 4.46Å; V380-V388 PolarHBondContact N-O 3.45Å; V380-V388 PolarHBondContact O-N 2.85Å
381M98.4Very high96.8Very high2 Ų225 Ų251%0.0115%0.147CC..EExtended strand (participates in β ladder)trans-128.7129.1-170.6-67.8142.1-78.200110.2T145 I175 F369 F371 T379T145-M381 WeakPolarHBondContact O-CG 3.44Å; T145-M381 VanDerWaalsContact O-SD 3.38Å; I175-M381 HydrophobicContact CD1-CB 4Å; I175-M381 HydrophobicContact CD1-CG 3.61Å; I175-M381 HydrophobicContact CD1-SD 3.21Å; I175-M381 WeakPolarHBondContact CD1-SD 3.15Å; I175-M381 HydrophobicContact CG1-SD 4.09Å; I175-M381 HydrophobicContact CG2-CB 4.37Å; F369-M381 HydrophobicContact CB-CB 4.32Å; F369-M381 HydrophobicContact CD1-CE 3.48Å; F369-M381 VanDerWaalsContact CD1-CE 3.48Å; F369-M381 HydrophobicContact CD1-SD 3.98Å; F369-M381 HydrophobicContact CE1-CE 4.08Å; F369-M381 PolarHBondContact N-O 2.74Å; F369-M381 PolarHBondContact O-N 3.39Å; F371-M381 HydrophobicContact CB-CE 3.67Å; T379-M381 HydrophobicContact CG2-CE 3.77Å; T379-M381 HydrophobicContact CG2-CG 3.96Å; T379-M381 HydrophobicContact CG2-SD 3.95Å; T379-M381 WeakPolarHBondContact O-CE 2.97Å
382F97.7Very high96.8Very high0 Ų024 Ų240%014%0.142CC..  trans-110.9156.6-174.7-67.8-73.6000113.1L302 M328 E330 V368 V380 S384 G385 A386L302-F382 HydrophobicContact CD1-CD2 3.83Å; L302-F382 HydrophobicContact CD1-CE2 3.94Å; L302-F382 HydrophobicContact CD1-CG 4.42Å; M328-F382 HydrophobicContact CB-CE2 4.23Å; M328-F382 HydrophobicContact CB-CZ 4.12Å; M328-F382 HydrophobicContact CG-CE2 4.02Å; M328-F382 HydrophobicContact CG-CZ 3.8Å; E330-F382 HydrophobicContact CB-CB 4.05Å; E330-F382 HydrophobicContact CB-CD1 3.38Å; E330-F382 HydrophobicContact CB-CE1 3.87Å; E330-F382 HydrophobicContact CB-CG 3.75Å; E330-F382 HydrophobicContact CG-CB 4.48Å; V368-F382 HydrophobicContact CB-CD1 4.01Å; V368-F382 HydrophobicContact CB-CE1 3.85Å; V368-F382 HydrophobicContact CG2-CD1 3.81Å; V368-F382 HydrophobicContact CG2-CE1 3.51Å; V368-F382 HydrophobicContact CG2-CZ 4.05Å; V380-F382 HydrophobicContact CG1-CE1 4.48Å; V380-F382 HydrophobicContact CG1-CE2 3.94Å; V380-F382 HydrophobicContact CG1-CZ 3.87Å; F382-S384 PolarHBondContact O-N 3.48Å; F382-S384 VanDerWaalsContact O-N 3.16Å; F382-G385 WeakPolarHBondContact O-CA 3.36Å; F382-G385 PolarHBondContact O-N 3.34Å; F382-A386 HydrophobicContact CB-CB 4.38Å; F382-A386 HydrophobicContact CD2-CB 4.35Å; F382-A386 PolarHBondContact N-O 3.39Å
383P94.4Very high96.6Very high71 Ų7126.9 Ų26.946%0.46115%0.151SC..THydrogen-bonded Turntrans-54.9-28.7178.3-29.836.6000115.8E330 G367 G385E330-P383 WeakPolarHBondContact OE1-CD 3.19Å; G367-P383 WeakPolarHBondContact O-CD 3.45Å; P383-G385 PolarHBondContact O-N 2.87Å
384S95.8Very high96.3Very high29 Ų2926.9 Ų26.920%0.20316%0.161CC..THydrogen-bonded Turntrans-67.1-10.8172.667.20000114.6E330 F382 A386 F407E330-S384 WeakPolarHBondContact OE1-CB 3.49Å; E330-S384 PolarHBondContact OE1-N 2.9Å; E330-S384 PolarHBondContact OE1-OG 2.83Å; E330-S384 WeakPolarHBondContact OE2-CB 3.5Å; E330-S384 PolarHBondContact OE2-OG 3.42Å; F382-S384 PolarHBondContact O-N 3.48Å; F382-S384 VanDerWaalsContact O-N 3.16Å; S384-A386 WeakPolarHBondContact OG-CB 3.01Å; S384-A386 PolarHBondContact OG-N 2.98Å; S384-F407 VanDerWaalsContact OG-CZ 3.3Å; S384-F407 WeakPolarHBondContact OG-CZ 3.39Å
385G96.9Very high95.9Very high7 Ų726.8 Ų26.87%0.07216%0.158CC..SBendtrans873.7-169.800000114.2G146 F382 P383 P404G146-G385 CarbonylContact C-O 3.56Å; F382-G385 WeakPolarHBondContact O-CA 3.36Å; F382-G385 PolarHBondContact O-N 3.34Å; P383-G385 PolarHBondContact O-N 2.87Å; G385-P404 WeakPolarHBondContact O-CD 3.41Å; G385-P404 WeakPolarHBondContact O-CG 3.14Å
386A98.6Very high95.8Very high0 Ų023 Ų230%013%0.132CC..  trans-66.1131172.500000111.1L302 F382 S384 L402 L403 F407L302-A386 HydrophobicContact CD1-CB 4.24Å; L302-A386 HydrophobicContact CD2-CB 3.72Å; F382-A386 HydrophobicContact CB-CB 4.38Å; F382-A386 HydrophobicContact CD2-CB 4.35Å; F382-A386 PolarHBondContact N-O 3.39Å; S384-A386 WeakPolarHBondContact OG-CB 3.01Å; S384-A386 PolarHBondContact OG-N 2.98Å; A386-L402 WeakPolarHBondContact CA-O 3.13Å; A386-L403 HydrophobicContact CB-CD2 3.67Å; A386-F407 HydrophobicContact CB-CE2 4.27Å; A386-F407 HydrophobicContact CB-CZ 3.97Å
387G98.6Very high95.8Very high0 Ų021.3 Ų21.30%012%0.122CC..EExtended strand (participates in β ladder)trans-115.9139.6174.600000111.7V380 V401 L402V380-G387 CarbonylContact O-C 3.6Å; V380-G387 WeakPolarHBondContact O-CA 3.25Å; G387-V401 CarbonylContact O-C 3.49Å; G387-V401 WeakPolarHBondContact O-CA 3.25Å; G387-L402 PolarHBondContact N-O 3Å; G387-L402 PolarHBondContact O-N 3.23Å
388V98.9Very high95.9Very high0 Ų020.1 Ų20.10%012%0.115CC..EExtended strand (participates in β ladder)trans-126.2114.3171.9-174.30000109V304 M328 T379 V380 V390 T399 T400 V401V304-V388 HydrophobicContact CG1-CG1 4.49Å; V304-V388 HydrophobicContact CG2-CG2 4Å; M328-V388 HydrophobicContact CE-CG1 4.47Å; M328-V388 HydrophobicContact SD-CB 3.66Å; M328-V388 HydrophobicContact SD-CG1 3.66Å; M328-V388 HydrophobicContact SD-CG2 4Å; T379-V388 CarbonylContact C-O 3.58Å; T379-V388 WeakPolarHBondContact CA-O 3.41Å; V380-V388 HydrophobicContact CB-CB 4.46Å; V380-V388 PolarHBondContact N-O 3.45Å; V380-V388 PolarHBondContact O-N 2.85Å; V388-V390 HydrophobicContact CG1-CG2 4.37Å; V388-T399 HydrophobicContact CG1-CG2 3.9Å; V388-T400 CarbonylContact C-O 3.59Å; V388-T400 WeakPolarHBondContact CA-O 3.41Å; V388-V401 HydrophobicContact CG2-CG2 4.49Å
389E98.8Very high95.9Very high24 Ų2420 Ų2011%0.11212%0.115CC..EExtended strand (participates in β ladder)trans-99.3122.6175.9-55.5-160.4145.100110.6T145 T379 R391 T399 T400T145-E389 WeakPolarHBondContact CB-OE1 3.37Å; T145-E389 VanDerWaalsContact CG2-OE1 3.3Å; T145-E389 WeakPolarHBondContact CG2-OE1 3.44Å; T145-E389 PolarHBondContact OG1-OE1 3.12Å; T379-E389 HydrophobicContact CG2-CG 4.28Å; E389-R391 IonicContact OE1-NH2 3.68Å; E389-R391 PolarHBondContact OE1-NH2 3.26Å; E389-R391 VanDerWaalsContact OE1-NH2 3.12Å; E389-R391 IonicContact OE2-CZ 3.92Å; E389-R391 IonicContact OE2-NE 3.54Å; E389-R391 IonicContact OE2-NH2 2.68Å; E389-R391 PolarHBondContact OE2-NH2 2.83Å; E389-T399 CarbonylContact O-C 3.6Å; E389-T399 VanDerWaalsContact O-CA 3.23Å; E389-T399 WeakPolarHBondContact O-CA 3.17Å; E389-T400 PolarHBondContact N-O 2.89Å; E389-T400 PolarHBondContact O-N 3.43Å
390V98.6Very high95.9Very high0 Ų020.2 Ų20.20%012%0.116CC..EExtended strand (participates in β ladder)trans-111.3122.5171.6-171.90000108.4V326 V338 L346 V378 V388 M397 T398 T399V326-V390 HydrophobicContact CB-CG2 4.41Å; V338-V390 HydrophobicContact CB-CB 4.36Å; V338-V390 HydrophobicContact CB-CG1 4.24Å; V338-V390 HydrophobicContact CB-CG2 4.12Å; V338-V390 HydrophobicContact CG1-CB 4.07Å; V338-V390 HydrophobicContact CG1-CG1 3.84Å; V338-V390 HydrophobicContact CG1-CG2 4.38Å; V338-V390 HydrophobicContact CG2-CB 4.49Å; V338-V390 HydrophobicContact CG2-CG2 3.99Å; L346-V390 HydrophobicContact CD1-CB 4.43Å; L346-V390 HydrophobicContact CD1-CG1 4.01Å; L346-V390 HydrophobicContact CD2-CG1 4.28Å; V378-V390 HydrophobicContact CB-CB 4.44Å; V378-V390 PolarHBondContact N-O 3.46Å; V378-V390 PolarHBondContact O-N 3.19Å; V388-V390 HydrophobicContact CG1-CG2 4.37Å; V390-M397 HydrophobicContact CG1-CG 3.55Å; V390-M397 HydrophobicContact CG1-SD 3.47Å; V390-M397 WeakPolarHBondContact CG1-SD 3.44Å; V390-T398 WeakPolarHBondContact CA-O 3.25Å; V390-T399 HydrophobicContact CG2-CG2 4.47Å
391R97.7Very high95.9Very high31 Ų3120.2 Ų20.212%0.11712%0.116CC..EExtended strand (participates in β ladder)trans-127.4120.6-176.5-57.4-65.1176.9-1041109.1T376 N377 V378 T379 E389 T398T376-R391 WeakPolarHBondContact O-CA 3.18Å; N377-R391 VanDerWaalsContact OD1-CD 3.26Å; N377-R391 WeakPolarHBondContact OD1-CD 3.34Å; V378-R391 PolarHBondContact O-NH1 2.78Å; T379-R391 PolarHBondContact OG1-NH1 3.4Å; T379-R391 PolarHBondContact OG1-NH2 2.85Å; E389-R391 IonicContact OE1-NH2 3.68Å; E389-R391 PolarHBondContact OE1-NH2 3.26Å; E389-R391 VanDerWaalsContact OE1-NH2 3.12Å; E389-R391 IonicContact OE2-CZ 3.92Å; E389-R391 IonicContact OE2-NE 3.54Å; E389-R391 IonicContact OE2-NH2 2.68Å; E389-R391 PolarHBondContact OE2-NH2 2.83Å; R391-T398 PolarHBondContact N-O 2.9Å; R391-T398 PolarHBondContact O-N 2.84Å
392R95.7Very high95.9Very high27 Ų2720.1 Ų20.110%0.10212%0.116CC..EExtended strand (participates in β ladder)trans-80.9127.5168.8-172.5173.3175.5156.5-3.1109.3L340 D341 N344 G345 L346 T376 G394L340-R392 HydrophobicContact CD2-CG 4.21Å; D341-R392 PolarHBondContact O-NH1 3.42Å; D341-R392 VanDerWaalsContact O-NH1 3.1Å; N344-R392 PolarHBondContact O-NE 3.44Å; N344-R392 PolarHBondContact OD1-NH2 3.19Å; G345-R392 VanDerWaalsContact N-NH1 3.18Å; G345-R392 PolarHBondContact O-NH1 2.97Å; L346-R392 HydrophobicContact CD1-CB 4.46Å; L346-R392 HydrophobicContact CD2-CB 4.07Å; L346-R392 HydrophobicContact CG-CB 4.1Å; T376-R392 HydrophobicContact CG2-CB 4.3Å; T376-R392 PolarHBondContact O-N 2.57Å; R392-G394 PolarHBondContact NE-O 3.37Å
393R91.3Very high96Very high73 Ų7320.1 Ų20.128%0.27512%0.116SC..EExtended strand (participates in β ladder)trans-128.497.5176.3-63.8-65.3-176.1-106.43.6108.2N377 E395 T396 A525N377-R393 PolarHBondContact OD1-NH1 2.94Å; R393-E395 PolarHBondContact O-N 2.97Å; R393-E395 VanDerWaalsContact O-N 3.16Å; R393-T396 PolarHBondContact N-O 2.04Å; R393-T396 PolarHBondContact O-N 2.82Å; R393-T396 VanDerWaalsContact O-N 3.12Å; R393-T396 PolarHBondContact O-OG1 2.86Å; R393-A525 HydrophobicContact CB-CB 3.82Å; R393-A525 VanDerWaalsContact O-CB 3.22Å; R393-A525 WeakPolarHBondContact O-CB 3.27Å
394G86.4Confident96.1Very high55 Ų5516.8 Ų16.857%0.5679%0.094SC*.THydrogen-bonded Turntrans61.3-115.1-171.300000111.6R392R392-G394 PolarHBondContact NE-O 3.37Å
395E85.4Confident96.1Very high86 Ų8618.4 Ų18.440%0.40210%0.098SC..THydrogen-bonded Turntrans-97.5-2.1-179.3-58.7-169.3151.200114.2K322 R393 I522K322-E395 PolarHBondContact NZ-O 2.9Å; R393-E395 PolarHBondContact O-N 2.97Å; R393-E395 VanDerWaalsContact O-N 3.16Å; E395-I522 HydrophobicContact CB-CG1 4.48Å
396T90.6Very high96.1Very high0 Ų023.4 Ų23.40%012%0.12CC..EExtended strand (participates in β ladder)trans-104.4155.7-179.866.20000111R393 I522 A525R393-T396 PolarHBondContact N-O 2.04Å; R393-T396 PolarHBondContact O-N 2.82Å; R393-T396 VanDerWaalsContact O-N 3.12Å; R393-T396 PolarHBondContact O-OG1 2.86Å; T396-I522 HydrophobicContact CG2-CB 4.26Å; T396-I522 HydrophobicContact CG2-CG1 4.26Å; T396-I522 HydrophobicContact CG2-CG2 3.64Å; T396-A525 HydrophobicContact CG2-CB 4.44Å; T396-A525 WeakPolarHBondContact OG1-CB 3.44Å
397M95.8Very high96Very high1 Ų123.4 Ų23.41%0.00512%0.12CC..EExtended strand (participates in β ladder)trans-118.7125173.1-169168.567.600108.5L323 T324 V326 L340 L346 V390L323-M397 HydrophobicContact CB-CB 4.4Å; L323-M397 HydrophobicContact CB-CE 4.12Å; L323-M397 HydrophobicContact CD2-CE 3.7Å; L323-M397 HydrophobicContact CG-CE 3.49Å; L323-M397 VanDerWaalsContact CG-CE 3.49Å; T324-M397 VanDerWaalsContact C-CE 3.5Å; V326-M397 HydrophobicContact CG2-CE 3.76Å; L340-M397 HydrophobicContact CD2-CB 4.14Å; L340-M397 HydrophobicContact CD2-SD 4.31Å; L340-M397 HydrophobicContact CG-SD 4.42Å; L346-M397 HydrophobicContact CD2-CG 4.36Å; L346-M397 HydrophobicContact CD2-SD 3.81Å; V390-M397 HydrophobicContact CG1-CG 3.55Å; V390-M397 HydrophobicContact CG1-SD 3.47Å; V390-M397 WeakPolarHBondContact CG1-SD 3.44Å
398T98.1Very high95.9Very high8 Ų827.6 Ų27.65%0.04914%0.138CC..EExtended strand (participates in β ladder)trans-105.2135.5176.3-64.20000108.7V269 V270 F271 V390 R391 S529V269-T398 HydrophobicContact CG2-CG2 3.75Å; V270-T398 CarbonylContact O-C 3.6Å; V270-T398 WeakPolarHBondContact O-CA 3.35Å; F271-T398 HydrophobicContact CB-CG2 3.92Å; V390-T398 WeakPolarHBondContact CA-O 3.25Å; R391-T398 PolarHBondContact N-O 2.9Å; R391-T398 PolarHBondContact O-N 2.84Å; T398-S529 WeakPolarHBondContact OG1-CB 3.31Å; T398-S529 PolarHBondContact OG1-OG 3.25Å
399T98.8Very high95.8Very high0 Ų032.5 Ų32.50%016%0.164CC..EExtended strand (participates in β ladder)trans-127.2116.9179.2-62.10000110.5V269 V270 L294 L323 V326 V388 E389 V390V269-T399 CarbonylContact C-O 3.58Å; V269-T399 WeakPolarHBondContact CA-O 3.4Å; V270-T399 PolarHBondContact N-O 2.88Å; V270-T399 PolarHBondContact O-N 3.33Å; L294-T399 HydrophobicContact CD1-CG2 4.5Å; L323-T399 VanDerWaalsContact CD2-OG1 3.31Å; L323-T399 WeakPolarHBondContact CD2-OG1 3.43Å; V326-T399 HydrophobicContact CG1-CG2 4.12Å; V326-T399 HydrophobicContact CG2-CG2 4.14Å; V326-T399 VanDerWaalsContact CG2-OG1 3.3Å; V326-T399 WeakPolarHBondContact CG2-OG1 3.44Å; V388-T399 HydrophobicContact CG1-CG2 3.9Å; E389-T399 CarbonylContact O-C 3.6Å; E389-T399 VanDerWaalsContact O-CA 3.23Å; E389-T399 WeakPolarHBondContact O-CA 3.17Å; V390-T399 HydrophobicContact CG2-CG2 4.47Å
400T98.9Very high95.7Very high10 Ų1033.1 Ų33.16%0.06117%0.172CC..EExtended strand (participates in β ladder)trans-106.4132.4174.9-55.40000109A268 V388 E389 L536A268-T400 CarbonylContact O-C 3.45Å; A268-T400 WeakPolarHBondContact O-CA 3.24Å; V388-T400 CarbonylContact C-O 3.59Å; V388-T400 WeakPolarHBondContact CA-O 3.41Å; E389-T400 PolarHBondContact N-O 2.89Å; E389-T400 PolarHBondContact O-N 3.43Å; T400-L536 HydrophobicContact CG2-CD2 3.57Å
401V98.9Very high95.6Very high0 Ų033.2 Ų33.20%017%0.172CC..EExtended strand (participates in β ladder)trans-110.6130172.6-174.70000108.7S267 A268 F279 V295 V304 G387 V388 L403 L415S267-V401 CarbonylContact C-O 3.57Å; S267-V401 VanDerWaalsContact CA-O 3.31Å; S267-V401 WeakPolarHBondContact CA-O 3.17Å; A268-V401 PolarHBondContact N-O 3.37Å; A268-V401 PolarHBondContact O-N 3.48Å; F279-V401 HydrophobicContact CE1-CB 4.45Å; F279-V401 HydrophobicContact CE1-CG1 4.43Å; F279-V401 HydrophobicContact CZ-CB 4.17Å; F279-V401 HydrophobicContact CZ-CG1 4.01Å; V295-V401 HydrophobicContact CG1-CG1 4.16Å; V295-V401 HydrophobicContact CG1-CG2 4.45Å; V304-V401 HydrophobicContact CG1-CG2 4.49Å; G387-V401 CarbonylContact O-C 3.49Å; G387-V401 WeakPolarHBondContact O-CA 3.25Å; V388-V401 HydrophobicContact CG2-CG2 4.49Å; V401-L403 HydrophobicContact CG1-CD2 3.87Å; V401-L403 HydrophobicContact CG1-CG 3.97Å; V401-L415 HydrophobicContact CB-CD1 3.99Å; V401-L415 HydrophobicContact CG2-CD1 3.6Å
402L98.8Very high95.6Very high0 Ų034.2 Ų34.20%018%0.182CC..EExtended strand (participates in β ladder)trans-112.8118.3176.8-71.1166.2000108.9A143 T145 P265 S266 A386 G387 L536 L540A143-L402 WeakPolarHBondContact O-CD1 3.35Å; T145-L402 WeakPolarHBondContact OG1-CD1 3.4Å; P265-L402 HydrophobicContact CB-CB 4.41Å; P265-L402 HydrophobicContact CB-CD2 4.47Å; P265-L402 HydrophobicContact CG-CD2 4.14Å; S266-L402 WeakPolarHBondContact O-CA 3.28Å; A386-L402 WeakPolarHBondContact CA-O 3.13Å; G387-L402 PolarHBondContact N-O 3Å; G387-L402 PolarHBondContact O-N 3.23Å; L402-L536 HydrophobicContact CD2-CD2 4.24Å; L402-L540 HydrophobicContact CD2-CD1 3.69Å
403L98.7Very high95.8Very high0 Ų033.1 Ų33.10%018%0.178CC..EExtended strand (participates in β ladder)trans-120127.8-179.8-62.7-174.4000111.3P265 S266 F279 V295 L302 A386 V401 F407 T411 M418P265-L403 CarbonylContact C-O 3.39Å; P265-L403 VanDerWaalsContact CA-O 3.23Å; P265-L403 WeakPolarHBondContact CA-O 3.43Å; P265-L403 WeakPolarHBondContact CB-O 3.22Å; S266-L403 PolarHBondContact N-O 3.04Å; S266-L403 PolarHBondContact O-N 3.49Å; F279-L403 HydrophobicContact CE1-CB 4.16Å; F279-L403 HydrophobicContact CE1-CD1 3.84Å; F279-L403 HydrophobicContact CE1-CG 3.76Å; F279-L403 HydrophobicContact CE2-CD1 3.75Å; F279-L403 HydrophobicContact CZ-CB 4.47Å; F279-L403 HydrophobicContact CZ-CD1 3.3Å; F279-L403 HydrophobicContact CZ-CG 3.65Å; V295-L403 HydrophobicContact CG2-CD1 4.25Å; L302-L403 HydrophobicContact CD2-CD2 3.55Å; A386-L403 HydrophobicContact CB-CD2 3.67Å; V401-L403 HydrophobicContact CG1-CD2 3.87Å; V401-L403 HydrophobicContact CG1-CG 3.97Å; L403-F407 HydrophobicContact CB-CB 4.08Å; L403-F407 HydrophobicContact CB-CD2 4.18Å; L403-F407 HydrophobicContact CB-CG 4.09Å; L403-F407 HydrophobicContact CD1-CB 4.18Å; L403-F407 HydrophobicContact CD1-CD1 4.05Å; L403-F407 HydrophobicContact CD1-CG 4.16Å; L403-F407 HydrophobicContact CD2-CD1 4.18Å; L403-F407 HydrophobicContact CD2-CD2 4.38Å; L403-F407 HydrophobicContact CD2-CE1 4.14Å; L403-F407 HydrophobicContact CD2-CE2 4.36Å; L403-F407 HydrophobicContact CD2-CG 4.29Å; L403-F407 HydrophobicContact CD2-CZ 4.23Å; L403-F407 HydrophobicContact CG-CG 4.41Å; L403-T411 HydrophobicContact CD1-CG2 3.58Å; L403-M418 HydrophobicContact CB-SD 3.86Å
404P97.7Very high96.1Very high1 Ų129.7 Ų29.71%0.00617%0.165CC..  trans-61157170.1-26.937.5000113.3R147 G385 E406 F407 M418R147-P404 HydrophobicContact CG-CG 4.48Å; G385-P404 WeakPolarHBondContact O-CD 3.41Å; G385-P404 WeakPolarHBondContact O-CG 3.14Å; P404-E406 WeakPolarHBondContact CB-OE2 3.43Å; P404-E406 PolarHBondContact O-N 3.42Å; P404-F407 HydrophobicContact CB-CD2 4.49Å; P404-F407 WeakPolarHBondContact O-CB 3.48Å; P404-F407 PolarHBondContact O-N 2.66Å; P404-M418 WeakPolarHBondContact O-CE 3.31Å
405E95.7Very high96.7Very high64 Ų6427 Ų2730%0.29914%0.138SC..G310 helixtrans-54.9-24.2-179.1-175.773.3-178.800112.8Q263 F407 K408Q263-E405 VanDerWaalsContact OE1-CB 3.24Å; E405-F407 PolarHBondContact O-N 2.91Å; E405-F407 VanDerWaalsContact O-N 3.08Å; E405-K408 WeakPolarHBondContact O-CB 3.42Å; E405-K408 PolarHBondContact O-N 2.9Å; E405-K408 WeakPolarHBondContact OE1-CD 3.46Å; E405-K408 WeakPolarHBondContact OE1-CE 3.47Å; E405-K408 IonicContact OE1-NZ 2.77Å; E405-K408 PolarHBondContact OE1-NZ 2.83Å
406E95.4Very high97.3Very high111 Ų11123 Ų2352%0.51912%0.12SC..G310 helixtrans-63.4-12.4175.9-60.581.3178.900114K300 P404 K408K300-E406 WeakPolarHBondContact CE-O 3.43Å; P404-E406 WeakPolarHBondContact CB-OE2 3.43Å; P404-E406 PolarHBondContact O-N 3.42Å; E406-K408 VanDerWaalsContact C-N 3.32Å
407F98.1Very high97.6Very high0 Ų026.4 Ų26.40%013%0.134CC..G310 helixtrans-84.6-5.2171.9-77-98.9000113.2K300 L302 S384 A386 L403 P404 E405 N409 S410 T411 M418K300-F407 HydrophobicContact CB-CD1 4.17Å; K300-F407 HydrophobicContact CB-CE1 3.41Å; K300-F407 VanDerWaalsContact CB-CE1 3.41Å; K300-F407 HydrophobicContact CB-CZ 3.63Å; K300-F407 HydrophobicContact CD-CZ 4.36Å; K300-F407 HydrophobicContact CG-CD1 3.83Å; K300-F407 HydrophobicContact CG-CD2 4.4Å; K300-F407 HydrophobicContact CG-CE1 3.49Å; K300-F407 VanDerWaalsContact CG-CE1 3.49Å; K300-F407 HydrophobicContact CG-CE2 4.09Å; K300-F407 HydrophobicContact CG-CG 4.28Å; K300-F407 HydrophobicContact CG-CZ 3.63Å; L302-F407 HydrophobicContact CB-CE1 3.93Å; L302-F407 HydrophobicContact CB-CZ 4.44Å; L302-F407 HydrophobicContact CD2-CD1 4.48Å; L302-F407 HydrophobicContact CD2-CE1 3.59Å; L302-F407 HydrophobicContact CD2-CZ 3.96Å; L302-F407 HydrophobicContact CG-CE1 4.42Å; S384-F407 VanDerWaalsContact OG-CZ 3.3Å; S384-F407 WeakPolarHBondContact OG-CZ 3.39Å; A386-F407 HydrophobicContact CB-CE2 4.27Å; A386-F407 HydrophobicContact CB-CZ 3.97Å; L403-F407 HydrophobicContact CB-CB 4.08Å; L403-F407 HydrophobicContact CB-CD2 4.18Å; L403-F407 HydrophobicContact CB-CG 4.09Å; L403-F407 HydrophobicContact CD1-CB 4.18Å; L403-F407 HydrophobicContact CD1-CD1 4.05Å; L403-F407 HydrophobicContact CD1-CG 4.16Å; L403-F407 HydrophobicContact CD2-CD1 4.18Å; L403-F407 HydrophobicContact CD2-CD2 4.38Å; L403-F407 HydrophobicContact CD2-CE1 4.14Å; L403-F407 HydrophobicContact CD2-CE2 4.36Å; L403-F407 HydrophobicContact CD2-CG 4.29Å; L403-F407 HydrophobicContact CD2-CZ 4.23Å; L403-F407 HydrophobicContact CG-CG 4.41Å; P404-F407 HydrophobicContact CB-CD2 4.49Å; P404-F407 WeakPolarHBondContact O-CB 3.48Å; P404-F407 PolarHBondContact O-N 2.66Å; E405-F407 PolarHBondContact O-N 2.91Å; E405-F407 VanDerWaalsContact O-N 3.08Å; F407-N409 PolarHBondContact O-N 3.45Å; F407-S410 WeakPolarHBondContact CA-OG 3.44Å; F407-S410 WeakPolarHBondContact O-CB 3.48Å; F407-S410 PolarHBondContact O-N 3.5Å; F407-S410 PolarHBondContact O-OG 2.93Å; F407-T411 HydrophobicContact CB-CG2 4.17Å; F407-T411 HydrophobicContact CD1-CG2 4.45Å; F407-M418 HydrophobicContact CB-CE 3.54Å; F407-M418 HydrophobicContact CB-SD 4.43Å
408K96.3Very high97.7Very high88 Ų8826.5 Ų26.538%0.38314%0.135SC..THydrogen-bonded Turntrans-59.1137-172.7-174.2163.1179.9163.30112E405 E406 S410 M418E405-K408 WeakPolarHBondContact O-CB 3.42Å; E405-K408 PolarHBondContact O-N 2.9Å; E405-K408 WeakPolarHBondContact OE1-CD 3.46Å; E405-K408 WeakPolarHBondContact OE1-CE 3.47Å; E405-K408 IonicContact OE1-NZ 2.77Å; E405-K408 PolarHBondContact OE1-NZ 2.83Å; E406-K408 VanDerWaalsContact C-N 3.32Å; K408-S410 PolarHBondContact O-N 3.31Å; K408-M418 CarbonylContact C-O 3.53Å; K408-M418 VanDerWaalsContact CA-O 3.3Å; K408-M418 WeakPolarHBondContact CA-O 3.45Å; K408-M418 HydrophobicContact CB-CE 4.04Å
409N96Very high97.7Very high103 Ų10327.4 Ų27.455%0.55114%0.14SC*.THydrogen-bonded Turntrans628.1-173.9-56.5-58.4000115.6F407 M418 N419F407-N409 PolarHBondContact O-N 3.45Å; N409-M418 PolarHBondContact N-O 2.86Å; N409-N419 WeakPolarHBondContact OD1-CB 3.48Å
410S96.1Very high97.5Very high38 Ų3830.6 Ų30.627%0.26617%0.172SC..THydrogen-bonded Turntrans-112-8.8-175.980.80000114.6S297 F407 K408S297-S410 WeakPolarHBondContact CA-O 3.37Å; S297-S410 PolarHBondContact OG-OG 3.49Å; F407-S410 WeakPolarHBondContact CA-OG 3.44Å; F407-S410 WeakPolarHBondContact O-CB 3.48Å; F407-S410 PolarHBondContact O-N 3.5Å; F407-S410 PolarHBondContact O-OG 2.93Å; K408-S410 PolarHBondContact O-N 3.31Å
411T98.3Very high97.5Very high1 Ų133.5 Ų33.51%0.00619%0.187CC..EExtended strand (participates in β ladder)trans-88.8144.3-17769.30000111.5V295 R296 L403 F407 G416 K417 M418V295-T411 HydrophobicContact CG2-CG2 4.05Å; R296-T411 WeakPolarHBondContact O-CA 3.39Å; L403-T411 HydrophobicContact CD1-CG2 3.58Å; F407-T411 HydrophobicContact CB-CG2 4.17Å; F407-T411 HydrophobicContact CD1-CG2 4.45Å; T411-G416 PolarHBondContact OG1-O 3.2Å; T411-K417 WeakPolarHBondContact OG1-CA 3.27Å; T411-M418 HydrophobicContact CG2-CB 4.12Å; T411-M418 PolarHBondContact OG1-N 3.06Å
412V97.9Very high97.4Very high53 Ų5335.4 Ų35.432%0.32120%0.204SC..EExtended strand (participates in β ladder)trans-141.3155.5169.1-61.30000109.3V295 R296 W450V295-V412 CarbonylContact C-O 3.56Å; V295-V412 WeakPolarHBondContact CA-O 3.45Å; R296-V412 HydrophobicContact CB-CG2 4.2Å; R296-V412 PolarHBondContact N-O 2.93Å; R296-V412 PolarHBondContact O-N 3.42Å; V412-W450 HydrophobicContact CB-CH2 3.72Å; V412-W450 HydrophobicContact CB-CZ2 4.44Å; V412-W450 HydrophobicContact CB-CZ3 4.41Å; V412-W450 HydrophobicContact CG2-CH2 3.97Å; V412-W450 HydrophobicContact CG2-CZ3 4.22Å
413G98.3Very high97.2Very high3 Ų343.1 Ų43.13%0.03124%0.237CC..SBendtrans130.9-168.3-179.400000112.1L294 L415 G416L294-G413 CarbonylContact O-C 3.58Å; G413-L415 PolarHBondContact O-N 2.72Å; G413-G416 PolarHBondContact O-N 3.29Å; G413-G416 VanDerWaalsContact O-N 3.17Å
414L98.8Very high97.1Very high1 Ų144.8 Ų44.81%0.00525%0.246CC..THydrogen-bonded Turntrans-64.2-25.5178.5-64.6179.6000113.5F276 Y284 F286 Y292 T293 L294 G416 F446 W450F276-L414 HydrophobicContact CD1-CB 4.15Å; F276-L414 HydrophobicContact CE1-CB 3.87Å; F276-L414 HydrophobicContact CE1-CD1 3.89Å; F276-L414 HydrophobicContact CZ-CD1 4Å; Y284-L414 WeakPolarHBondContact OH-CB 3.23Å; Y284-L414 PolarHBondContact OH-O 3.23Å; F286-L414 HydrophobicContact CD1-CD1 4.19Å; F286-L414 HydrophobicContact CE1-CD1 4.35Å; Y292-L414 HydrophobicContact CG-CD1 4.27Å; T293-L414 WeakPolarHBondContact O-CG 3.28Å; T293-L414 PolarHBondContact O-N 3.12Å; L294-L414 HydrophobicContact CD2-CD1 4.19Å; L294-L414 PolarHBondContact O-N 3.11Å; L414-G416 PolarHBondContact O-N 2.68Å; L414-F446 HydrophobicContact CD2-CE1 4.13Å; L414-F446 HydrophobicContact CD2-CZ 3.99Å; L414-W450 HydrophobicContact CD2-CB 3.85Å; L414-W450 HydrophobicContact CD2-CG 3.95Å; L414-W450 HydrophobicContact CG-CB 4.01Å; L414-W450 HydrophobicContact CG-CG 4.29Å
415L98.8Very high97.1Very high0 Ų044.9 Ų44.90%025%0.246CC..THydrogen-bonded Turntrans-84.18.5177.5-59178.7000113.7A268 V270 F276 T278 F279 L294 V295 V401 G413A268-L415 HydrophobicContact CB-CB 3.94Å; A268-L415 HydrophobicContact CB-CD1 4.06Å; A268-L415 HydrophobicContact CB-CD2 3.97Å; A268-L415 HydrophobicContact CB-CG 4.19Å; V270-L415 HydrophobicContact CG2-CD2 3.9Å; F276-L415 HydrophobicContact CD1-CD2 4.13Å; T278-L415 WeakPolarHBondContact CA-O 3.13Å; T278-L415 VanDerWaalsContact CB-O 3.25Å; T278-L415 WeakPolarHBondContact CB-O 3.15Å; F279-L415 HydrophobicContact CD2-CB 4.17Å; F279-L415 WeakPolarHBondContact CD2-O 3.31Å; F279-L415 HydrophobicContact CE2-CB 3.68Å; F279-L415 HydrophobicContact CZ-CB 4.32Å; F279-L415 HydrophobicContact CZ-CD1 4.38Å; F279-L415 PolarHBondContact N-O 2.92Å; L294-L415 HydrophobicContact CB-CD1 4.12Å; L294-L415 HydrophobicContact CB-CG 4.27Å; L294-L415 WeakPolarHBondContact O-CB 3.46Å; L294-L415 WeakPolarHBondContact O-CG 3.36Å; L294-L415 PolarHBondContact O-N 3.36Å; V295-L415 HydrophobicContact CB-CB 4.36Å; V295-L415 HydrophobicContact CB-CD1 4.22Å; V295-L415 HydrophobicContact CG1-CD1 4.17Å; V401-L415 HydrophobicContact CB-CD1 3.99Å; V401-L415 HydrophobicContact CG2-CD1 3.6Å; G413-L415 PolarHBondContact O-N 2.72Å
416G97.9Very high97.2Very high1 Ų141.9 Ų41.91%0.0123%0.232CC..  trans79.4-174.5172.600000114.7T411 G413 L414 D425T411-G416 PolarHBondContact OG1-O 3.2Å; G413-G416 PolarHBondContact O-N 3.29Å; G413-G416 VanDerWaalsContact O-N 3.17Å; L414-G416 PolarHBondContact O-N 2.68Å; G416-D425 VanDerWaalsContact CA-OD1 3.32Å; G416-D425 WeakPolarHBondContact CA-OD1 3.01Å
417K97.4Very high97.3Very high71 Ų7137.7 Ų37.731%0.30922%0.217SC..  trans-106.199.3-177.6-179.4178.2161.5-144.30108.4D280 T411 N419 D424 D425D280-K417 VanDerWaalsContact OD2-O 3.04Å; T411-K417 WeakPolarHBondContact OG1-CA 3.27Å; K417-N419 WeakPolarHBondContact CE-ND2 3.42Å; K417-N419 PolarHBondContact NZ-ND2 3.24Å; K417-N419 VanDerWaalsContact O-CG 3.3Å; K417-N419 PolarHBondContact O-N 3.43Å; K417-N419 PolarHBondContact O-ND2 3.27Å; K417-D424 WeakPolarHBondContact CD-OD2 3.44Å; K417-D424 IonicContact NZ-OD2 3.66Å; K417-D424 PolarHBondContact NZ-OD2 2.66Å; K417-D425 PolarHBondContact N-OD1 3.35Å
418M97.6Very high97.3Very high4 Ų439.4 Ų39.42%0.0223%0.226CC..  trans-60.894.6-177.7-171.6-177.990.700111.1F279 L403 P404 F407 K408 N409 T411F279-M418 HydrophobicContact CB-CB 3.81Å; F279-M418 HydrophobicContact CB-CG 3.73Å; F279-M418 HydrophobicContact CB-SD 4.47Å; F279-M418 HydrophobicContact CD1-SD 4.22Å; F279-M418 HydrophobicContact CD2-CB 3.99Å; F279-M418 HydrophobicContact CG-CB 3.97Å; F279-M418 HydrophobicContact CG-CG 4.05Å; F279-M418 HydrophobicContact CG-SD 4.25Å; L403-M418 HydrophobicContact CB-SD 3.86Å; P404-M418 WeakPolarHBondContact O-CE 3.31Å; F407-M418 HydrophobicContact CB-CE 3.54Å; F407-M418 HydrophobicContact CB-SD 4.43Å; K408-M418 CarbonylContact C-O 3.53Å; K408-M418 VanDerWaalsContact CA-O 3.3Å; K408-M418 WeakPolarHBondContact CA-O 3.45Å; K408-M418 HydrophobicContact CB-CE 4.04Å; N409-M418 PolarHBondContact N-O 2.86Å; T411-M418 HydrophobicContact CG2-CB 4.12Å; T411-M418 PolarHBondContact OG1-N 3.06Å
419N96.9Very high97.3Very high27 Ų2738.5 Ų38.514%0.14423%0.231CC..SBendtrans-145.6-7.3-17969.536000114.1D280 N409 K417 D421 D424D280-N419 PolarHBondContact OD1-N 3.38Å; D280-N419 PolarHBondContact OD2-N 2.9Å; D280-N419 PolarHBondContact OD2-OD1 3.15Å; N409-N419 WeakPolarHBondContact OD1-CB 3.48Å; K417-N419 WeakPolarHBondContact CE-ND2 3.42Å; K417-N419 PolarHBondContact NZ-ND2 3.24Å; K417-N419 VanDerWaalsContact O-CG 3.3Å; K417-N419 PolarHBondContact O-N 3.43Å; K417-N419 PolarHBondContact O-ND2 3.27Å; N419-D421 WeakPolarHBondContact OD1-CA 3.48Å; N419-D421 WeakPolarHBondContact OD1-CB 3.36Å; N419-D421 PolarHBondContact OD1-N 3.44Å; N419-D424 VanDerWaalsContact ND2-CG 3.28Å; N419-D424 PolarHBondContact ND2-OD1 2.82Å; N419-D424 PolarHBondContact ND2-OD2 3.49Å
420G96.4Very high97.3Very high67 Ų6739 Ų3969%0.69123%0.233SC*.SBendtrans89.511.9-175.800000114.6D280D280-G420 WeakPolarHBondContact OD1-CA 3.38Å; D280-G420 PolarHBondContact OD1-N 3.41Å; D280-G420 WeakPolarHBondContact OD2-CA 3.37Å; D280-G420 PolarHBondContact OD2-N 2.78Å
421D97.2Very high97.2Very high70 Ų7039.8 Ų39.837%0.37425%0.247SC..  trans-124.294.5-179.8-1714.4000111.5D280 N419 K423 D424D280-D421 PolarHBondContact OD2-N 3.35Å; N419-D421 WeakPolarHBondContact OD1-CA 3.48Å; N419-D421 WeakPolarHBondContact OD1-CB 3.36Å; N419-D421 PolarHBondContact OD1-N 3.44Å; D421-K423 PolarHBondContact O-N 2.96Å; D421-K423 WeakPolarHBondContact OD1-CB 3.1Å; D421-K423 WeakPolarHBondContact OD1-CG 3.48Å; D421-K423 PolarHBondContact OD1-N 2.78Å; D421-K423 VanDerWaalsContact OD1-N 3.11Å; D421-D424 PolarHBondContact O-N 3.35Å; D421-D424 VanDerWaalsContact O-OD1 3.07Å
422A96.5Very high97.1Very high41 Ų4145.1 Ų45.134%0.33927%0.272SS..THydrogen-bonded Turntrans-53.9-12.3175.600000115.4V282V282-A422 HydrophobicContact CG2-CB 3.56Å; V282-A422 WeakPolarHBondContact CG2-O 3.36Å
423K95.8Very high97.1Very high162 Ų16245.9 Ų45.970%0.70427%0.274SS*.THydrogen-bonded Turntrans-81-22.3-178.8-63.5173.8-175.1169.10113.9D421D421-K423 PolarHBondContact O-N 2.96Å; D421-K423 WeakPolarHBondContact OD1-CB 3.1Å; D421-K423 WeakPolarHBondContact OD1-CG 3.48Å; D421-K423 PolarHBondContact OD1-N 2.78Å; D421-K423 VanDerWaalsContact OD1-N 3.11Å
424D95.9Very high97Very high34 Ų3446 Ų4618%0.18227%0.274CS..SBendtrans-107.65-178.282-16000114K417 N419 D421 L433K417-D424 WeakPolarHBondContact CD-OD2 3.44Å; K417-D424 IonicContact NZ-OD2 3.66Å; K417-D424 PolarHBondContact NZ-OD2 2.66Å; N419-D424 VanDerWaalsContact ND2-CG 3.28Å; N419-D424 PolarHBondContact ND2-OD1 2.82Å; N419-D424 PolarHBondContact ND2-OD2 3.49Å; D421-D424 PolarHBondContact O-N 3.35Å; D421-D424 VanDerWaalsContact O-OD1 3.07Å; D424-L433 HydrophobicContact CB-CD2 4.32Å
425D97.4Very high96.7Very high3 Ų353.1 Ų53.12%0.01631%0.307CS..SBendtrans-66.7-38.6178.7-95-15.8000114T278 D280 V282 G416 K417 A427T278-D425 WeakPolarHBondContact CB-OD2 3.46Å; T278-D425 HydrophobicContact CG2-CB 4.19Å; T278-D425 PolarHBondContact OG1-OD2 3.46Å; D280-D425 WeakPolarHBondContact CB-OD2 3.18Å; V282-D425 HydrophobicContact CB-CB 4.33Å; V282-D425 HydrophobicContact CG2-CB 3.83Å; V282-D425 WeakPolarHBondContact CG2-OD2 3.3Å; G416-D425 VanDerWaalsContact CA-OD1 3.32Å; G416-D425 WeakPolarHBondContact CA-OD1 3.01Å; K417-D425 PolarHBondContact N-OD1 3.35Å; D425-A427 VanDerWaalsContact C-N 3.3Å; D425-A427 PolarHBondContact O-N 3.44Å; D425-A427 VanDerWaalsContact O-N 3.12Å
426L97.8Very high96.4Very high2 Ų256.7 Ų56.71%0.0133%0.326CS..SBendtrans-91.666.2-177.4-54.9-171.6000110.6V282 Y284 V434 H437 L443 F446V282-L426 HydrophobicContact CG1-CD1 3.94Å; V282-L426 HydrophobicContact CG1-CD2 3.98Å; V282-L426 HydrophobicContact CG1-CG 3.97Å; Y284-L426 HydrophobicContact CD1-CD2 3.73Å; Y284-L426 HydrophobicContact CE1-CD2 3.73Å; Y284-L426 HydrophobicContact CG-CD2 4.39Å; L426-V434 HydrophobicContact CB-CB 4Å; L426-V434 HydrophobicContact CB-CG2 3.89Å; L426-V434 WeakPolarHBondContact O-CG2 3.24Å; L426-V434 PolarHBondContact O-N 2.77Å; L426-H437 HydrophobicContact CD1-CB 4.47Å; L426-L443 HydrophobicContact CD1-CD2 3.69Å; L426-F446 HydrophobicContact CD2-CE1 3.83Å; L426-F446 HydrophobicContact CD2-CZ 3.81Å
427A97.3Very high96.1Very high23 Ų2360.5 Ų60.519%0.1934%0.344CS..BIsolated β-bridgetrans-100.3129.4174.800000110.9D425 Q432 L433 F446 W450D425-A427 VanDerWaalsContact C-N 3.3Å; D425-A427 PolarHBondContact O-N 3.44Å; D425-A427 VanDerWaalsContact O-N 3.12Å; A427-Q432 CarbonylContact C-O 3.59Å; A427-Q432 WeakPolarHBondContact CA-O 3.37Å; A427-L433 HydrophobicContact CB-CD2 3.84Å; A427-F446 VanDerWaalsContact O-CE2 3.26Å; A427-F446 WeakPolarHBondContact O-CE2 3.44Å; A427-W450 WeakPolarHBondContact O-CZ2 3.49Å; A427-W450 PolarHBondContact O-NE1 3.3Å
428L97.9Very high95.8Very high36 Ų3662.3 Ų62.319%0.18837%0.366CS..  trans-60.5161.9169.2-78.380.5000110.5N430 G431 Q432 V434 F446 S449L428-N430 VanDerWaalsContact CB-OD1 3.24Å; L428-N430 WeakPolarHBondContact CB-OD1 3.44Å; L428-N430 PolarHBondContact O-N 2.86Å; L428-G431 WeakPolarHBondContact O-CA 3.21Å; L428-G431 PolarHBondContact O-N 2.99Å; L428-Q432 WeakPolarHBondContact CD1-O 3.31Å; L428-Q432 PolarHBondContact N-O 2.67Å; L428-V434 HydrophobicContact CD1-CG2 4.14Å; L428-F446 HydrophobicContact CD1-CB 4.26Å; L428-F446 HydrophobicContact CG-CB 4.47Å; L428-S449 WeakPolarHBondContact CA-OG 3.37Å
429S96.3Very high95.6Very high69 Ų6964.7 Ų64.748%0.48338%0.378SS..THydrogen-bonded Turntrans-58.9-20.2177.658.40000114.6S449S429-S449 WeakPolarHBondContact CB-O 3.5Å; S429-S449 PolarHBondContact N-OG 3.3Å; S429-S449 VanDerWaalsContact N-OG 3.11Å; S429-S449 PolarHBondContact OG-O 2.65Å
430N95.9Very high95.4Very high113 Ų11365.6 Ų65.660%0.60439%0.386SS*.THydrogen-bonded Turntrans-87.3-0173.170.1-0.4000114.1L428 Q432L428-N430 VanDerWaalsContact CB-OD1 3.24Å; L428-N430 WeakPolarHBondContact CB-OD1 3.44Å; L428-N430 PolarHBondContact O-N 2.86Å; N430-Q432 VanDerWaalsContact OD1-CB 3.31Å; N430-Q432 WeakPolarHBondContact OD1-CB 3.3Å; N430-Q432 PolarHBondContact OD1-N 2.8Å
431G94.8Very high95.3Very high54 Ų5466.9 Ų66.956%0.55737%0.374SS*.SBendtrans87.7-1.6-179.600000115.7L428L428-G431 WeakPolarHBondContact O-CA 3.21Å; L428-G431 PolarHBondContact O-N 2.99Å
432Q96.4Very high95.2Very high113 Ų11365.9 Ų65.953%0.52837%0.367SS..PPolyproline II helixtrans-73.5136.2175.7-175.6178.5-25.600110.8A427 L428 N430A427-Q432 CarbonylContact C-O 3.59Å; A427-Q432 WeakPolarHBondContact CA-O 3.37Å; L428-Q432 WeakPolarHBondContact CD1-O 3.31Å; L428-Q432 PolarHBondContact N-O 2.67Å; N430-Q432 VanDerWaalsContact OD1-CB 3.31Å; N430-Q432 WeakPolarHBondContact OD1-CB 3.3Å; N430-Q432 PolarHBondContact OD1-N 2.8Å
433L96.9Very high95.2Very high69 Ų6964.5 Ų64.536%0.36135%0.354SS..BIsolated β-bridgetrans-81.7142.9177-62.3178.8000112.3D424 A427 Q435D424-L433 HydrophobicContact CB-CD2 4.32Å; A427-L433 HydrophobicContact CB-CD2 3.84Å; L433-Q435 PolarHBondContact O-N 3.37Å; L433-Q435 PolarHBondContact O-NE2 3.12Å
434V96.5Very high95.2Very high7 Ų757.6 Ų57.64%0.04232%0.324CS..PPolyproline II helixtrans-59.9132164.8177.70000108.9L426 L428 E442 L443 F446L426-V434 HydrophobicContact CB-CB 4Å; L426-V434 HydrophobicContact CB-CG2 3.89Å; L426-V434 WeakPolarHBondContact O-CG2 3.24Å; L426-V434 PolarHBondContact O-N 2.77Å; L428-V434 HydrophobicContact CD1-CG2 4.14Å; V434-E442 HydrophobicContact CG1-CG 3.97Å; V434-L443 HydrophobicContact CG1-CD2 4.38Å; V434-F446 HydrophobicContact CG2-CB 3.52Å; V434-F446 HydrophobicContact CG2-CD2 4.21Å; V434-F446 HydrophobicContact CG2-CG 3.87Å
435Q93.2Very high95.2Very high149 Ų14959.3 Ų59.370%0.69634%0.338SS*.SBendtrans-89.3-41.8-178.7-59.2-58.3-58.500111.6L433 E442L433-Q435 PolarHBondContact O-N 3.37Å; L433-Q435 PolarHBondContact O-NE2 3.12Å; Q435-E442 WeakPolarHBondContact CB-OE1 3.46Å; Q435-E442 PolarHBondContact N-OE1 3.07Å
436N92.8Very high95.2Very high76 Ų7659.1 Ų59.141%0.40634%0.337SS..  trans-119.498.1179.5-172.6-4.2000111.8S438 N439 E442N436-S438 PolarHBondContact O-N 2.83Å; N436-S438 VanDerWaalsContact O-N 3.1Å; N436-S438 WeakPolarHBondContact OD1-CB 3.28Å; N436-S438 PolarHBondContact OD1-N 2.82Å; N436-N439 HydrophobicContact CB-CB 3.92Å; N436-N439 WeakPolarHBondContact O-CB 3.5Å; N436-N439 PolarHBondContact O-N 3.31Å; N436-E442 VanDerWaalsContact CB-OE2 3.29Å; N436-E442 WeakPolarHBondContact CB-OE2 3.49Å; N436-E442 PolarHBondContact N-OE1 2.94Å; N436-E442 PolarHBondContact N-OE2 3.27Å; N436-E442 VanDerWaalsContact N-OE2 3.11Å
437H91.8Very high95.2Very high80 Ų8059 Ų5937%0.3734%0.337SS..THydrogen-bonded Turntrans-65.6-11.5178.2-63.2-171.5000113.6L426 L443L426-H437 HydrophobicContact CD1-CB 4.47Å; H437-L443 WeakPolarHBondContact O-CD1 3.42Å
438S90.1Very high95.2Very high110 Ų11058.9 Ų58.977%0.76934%0.336SS*.THydrogen-bonded Turntrans-95.8-4.2175.6-55.30000113.3N436 P440N436-S438 PolarHBondContact O-N 2.83Å; N436-S438 VanDerWaalsContact O-N 3.1Å; N436-S438 WeakPolarHBondContact OD1-CB 3.28Å; N436-S438 PolarHBondContact OD1-N 2.82Å; S438-P440 VanDerWaalsContact O-CD 3.32Å; S438-P440 WeakPolarHBondContact O-CD 3.32Å
439N94.3Very high95.2Very high53 Ų5358.6 Ų58.628%0.28334%0.336SS..  trans-90.5106.4178.6-179.4-12.5000109.9N436 E441 E442 L443N436-N439 HydrophobicContact CB-CB 3.92Å; N436-N439 WeakPolarHBondContact O-CB 3.5Å; N436-N439 PolarHBondContact O-N 3.31Å; N439-E441 VanDerWaalsContact C-N 3.3Å; N439-E441 PolarHBondContact O-N 2.9Å; N439-E441 PolarHBondContact OD1-N 3.06Å; N439-E441 VanDerWaalsContact OD1-N 3.16Å; N439-E441 PolarHBondContact OD1-OE2 3.29Å; N439-E442 HydrophobicContact CB-CB 3.86Å; N439-E442 PolarHBondContact O-N 3.26Å; N439-E442 PolarHBondContact OD1-N 3.45Å; N439-L443 WeakPolarHBondContact O-CG 3.44Å; N439-L443 PolarHBondContact O-N 3.15Å
440P92Very high95.3Very high47 Ų4756.4 Ų56.431%0.30532%0.318SS..Hα-helixtrans-67.6-28.2-174.527.7-32.8000113.1S438 F444 F484S438-P440 VanDerWaalsContact O-CD 3.32Å; S438-P440 WeakPolarHBondContact O-CD 3.32Å; P440-F444 VanDerWaalsContact O-CB 3.3Å; P440-F444 WeakPolarHBondContact O-CB 3.41Å; P440-F444 PolarHBondContact O-N 2.84Å; P440-F484 HydrophobicContact CB-CB 3.85Å; P440-F484 HydrophobicContact CB-CD1 3.82Å; P440-F484 HydrophobicContact CB-CG 4.08Å; P440-F484 HydrophobicContact CG-CB 3.79Å; P440-F484 HydrophobicContact CG-CD1 4.45Å; P440-F484 HydrophobicContact CG-CG 4.24Å
441E93.6Very high95.4Very high94 Ų9452.6 Ų52.644%0.43930%0.302SS..Hα-helixtrans-69.6-35.6173.9-66.981177.500112.3N439 F444 S445 F484N439-E441 VanDerWaalsContact C-N 3.3Å; N439-E441 PolarHBondContact O-N 2.9Å; N439-E441 PolarHBondContact OD1-N 3.06Å; N439-E441 VanDerWaalsContact OD1-N 3.16Å; N439-E441 PolarHBondContact OD1-OE2 3.29Å; E441-F444 PolarHBondContact O-N 2.97Å; E441-S445 PolarHBondContact O-N 2.71Å; E441-S445 PolarHBondContact O-OG 3.44Å; E441-F484 HydrophobicContact CG-CD2 4.16Å; E441-F484 HydrophobicContact CG-CE2 3.81Å; E441-F484 HydrophobicContact CG-CZ 4.1Å
442E95.3Very high95.5Very high48 Ų4850.3 Ų50.322%0.22428%0.277CS..Hα-helixtrans-70.3-43.2175.4-162.7179.3166.500111V434 Q435 N436 N439 F444 S445 F446V434-E442 HydrophobicContact CG1-CG 3.97Å; Q435-E442 WeakPolarHBondContact CB-OE1 3.46Å; Q435-E442 PolarHBondContact N-OE1 3.07Å; N436-E442 VanDerWaalsContact CB-OE2 3.29Å; N436-E442 WeakPolarHBondContact CB-OE2 3.49Å; N436-E442 PolarHBondContact N-OE1 2.94Å; N436-E442 PolarHBondContact N-OE2 3.27Å; N436-E442 VanDerWaalsContact N-OE2 3.11Å; N439-E442 HydrophobicContact CB-CB 3.86Å; N439-E442 PolarHBondContact O-N 3.26Å; N439-E442 PolarHBondContact OD1-N 3.45Å; E442-F444 VanDerWaalsContact C-N 3.28Å; E442-F444 PolarHBondContact O-N 2.68Å; E442-S445 WeakPolarHBondContact O-CB 3.41Å; E442-S445 PolarHBondContact O-N 3.4Å; E442-F446 PolarHBondContact O-N 3.13Å
443L96.2Very high95.4Very high13 Ų1351.3 Ų51.37%0.06828%0.282CS..Hα-helixtrans-60.2-38.6171.8-69.5176.5000112L426 V434 H437 N439 F446 G447L426-L443 HydrophobicContact CD1-CD2 3.69Å; V434-L443 HydrophobicContact CG1-CD2 4.38Å; H437-L443 WeakPolarHBondContact O-CD1 3.42Å; N439-L443 WeakPolarHBondContact O-CG 3.44Å; N439-L443 PolarHBondContact O-N 3.15Å; L443-F446 WeakPolarHBondContact O-CB 3.24Å; L443-F446 WeakPolarHBondContact O-CD1 3.25Å; L443-F446 PolarHBondContact O-N 3.49Å; L443-G447 PolarHBondContact O-N 2.81Å
444F96.4Very high94.9Very high16 Ų1652.9 Ų52.97%0.0729%0.29CS..Hα-helixtrans-64.8-42.7175.5-175.1-96.6000112.3F286 P440 E441 E442 F446 G447 A448 H476 F480 M481 P482 F484F286-F444 AromaticContact CD2-CD2 3.93Å; F286-F444 HydrophobicContact CD2-CD2 3.93Å; F286-F444 AromaticContact CE2-CD2 3.78Å; F286-F444 HydrophobicContact CE2-CD2 3.78Å; F286-F444 HydrophobicContact CE2-CE2 4.02Å; F286-F444 HydrophobicContact CE2-CG 4.34Å; F286-F444 WeakPolarHBondContact CE2-O 3.45Å; P440-F444 VanDerWaalsContact O-CB 3.3Å; P440-F444 WeakPolarHBondContact O-CB 3.41Å; P440-F444 PolarHBondContact O-N 2.84Å; E441-F444 PolarHBondContact O-N 2.97Å; E442-F444 VanDerWaalsContact C-N 3.28Å; E442-F444 PolarHBondContact O-N 2.68Å; F444-F446 VanDerWaalsContact C-N 3.32Å; F444-F446 PolarHBondContact O-N 3.28Å; F444-G447 PolarHBondContact O-N 3.49Å; F444-A448 VanDerWaalsContact O-CB 3.3Å; F444-A448 WeakPolarHBondContact O-CB 3.15Å; F444-A448 PolarHBondContact O-N 3.27Å; F444-H476 AromaticContact CE1-CE1 3.94Å; F444-H476 AromaticContact CZ-CE1 3.68Å; F444-F480 WeakPolarHBondContact CZ-O 3.27Å; F444-M481 HydrophobicContact CE1-SD 4.27Å; F444-P482 HydrophobicContact CD2-CG 3.72Å; F444-P482 VanDerWaalsContact CE2-CD 3.42Å; F444-P482 HydrophobicContact CE2-CG 3.6Å; F444-P482 HydrophobicContact CZ-CG 4.46Å; F444-F484 HydrophobicContact CB-CE1 3.7Å; F444-F484 HydrophobicContact CB-CZ 4.22Å; F444-F484 HydrophobicContact CD1-CZ 4.49Å; F444-F484 HydrophobicContact CD2-CE1 4.04Å; F444-F484 AromaticContact CG-CE1 3.89Å; F444-F484 HydrophobicContact CG-CE1 3.89Å; F444-F484 HydrophobicContact CG-CZ 4.17Å
445S96.3Very high94.6Very high70 Ų7058.9 Ų58.949%0.4933%0.328SS..Hα-helixtrans-63.2-39.6174.8-57.80000111.6E441 E442 S449E441-S445 PolarHBondContact O-N 2.71Å; E441-S445 PolarHBondContact O-OG 3.44Å; E442-S445 WeakPolarHBondContact O-CB 3.41Å; E442-S445 PolarHBondContact O-N 3.4Å; S445-S449 PolarHBondContact O-N 2.87Å; S445-S449 VanDerWaalsContact O-N 3.09Å
446F97.6Very high94.6Very high0 Ų054.2 Ų54.20%031%0.311CS..Hα-helixtrans-59.4-51.1171.8148.8-103.3000111.8Y284 L414 L426 A427 L428 V434 E442 L443 F444 A448 S449 W450Y284-F446 HydrophobicContact CD2-CE1 4.29Å; Y284-F446 HydrophobicContact CE1-CE1 4.25Å; Y284-F446 HydrophobicContact CE2-CD1 4.34Å; Y284-F446 AromaticContact CE2-CE1 3.61Å; Y284-F446 HydrophobicContact CE2-CE1 3.61Å; Y284-F446 AromaticContact CZ-CE1 3.59Å; L414-F446 HydrophobicContact CD2-CE1 4.13Å; L414-F446 HydrophobicContact CD2-CZ 3.99Å; L426-F446 HydrophobicContact CD2-CE1 3.83Å; L426-F446 HydrophobicContact CD2-CZ 3.81Å; A427-F446 VanDerWaalsContact O-CE2 3.26Å; A427-F446 WeakPolarHBondContact O-CE2 3.44Å; L428-F446 HydrophobicContact CD1-CB 4.26Å; L428-F446 HydrophobicContact CG-CB 4.47Å; V434-F446 HydrophobicContact CG2-CB 3.52Å; V434-F446 HydrophobicContact CG2-CD2 4.21Å; V434-F446 HydrophobicContact CG2-CG 3.87Å; E442-F446 PolarHBondContact O-N 3.13Å; L443-F446 WeakPolarHBondContact O-CB 3.24Å; L443-F446 WeakPolarHBondContact O-CD1 3.25Å; L443-F446 PolarHBondContact O-N 3.49Å; F444-F446 VanDerWaalsContact C-N 3.32Å; F444-F446 PolarHBondContact O-N 3.28Å; F446-A448 VanDerWaalsContact C-N 3.34Å; F446-A448 PolarHBondContact O-N 2.89Å; F446-S449 WeakPolarHBondContact O-CB 3.08Å; F446-S449 PolarHBondContact O-N 3.36Å; F446-S449 VanDerWaalsContact O-N 3.15Å; F446-S449 PolarHBondContact O-OG 3.28Å; F446-W450 AromaticContact CE2-CD1 3.78Å; F446-W450 AromaticContact CE2-NE1 3.53Å
447G97.7Very high94.8Very high0 Ų051.8 Ų51.80%030%0.302CS..Hα-helixtrans-61.8-42.6179.900000112.6L443 F444 S449 W450L443-G447 PolarHBondContact O-N 2.81Å; F444-G447 PolarHBondContact O-N 3.49Å; G447-S449 PolarHBondContact O-N 3.07Å; G447-W450 PolarHBondContact O-N 2.97Å; G447-W450 VanDerWaalsContact O-N 3.14Å
448A97.7Very high95.1Very high20 Ų2049.1 Ų49.117%0.16529%0.29CS..Hα-helixtrans-60.7-32.1176.500000112.9F444 F446 W450 A451F444-A448 VanDerWaalsContact O-CB 3.3Å; F444-A448 WeakPolarHBondContact O-CB 3.15Å; F444-A448 PolarHBondContact O-N 3.27Å; F446-A448 VanDerWaalsContact C-N 3.34Å; F446-A448 PolarHBondContact O-N 2.89Å; A448-W450 PolarHBondContact O-N 3.47Å; A448-A451 WeakPolarHBondContact O-CB 3.22Å; A448-A451 PolarHBondContact O-N 3.09Å
449S98Very high95.5Very high29 Ų2944.2 Ų44.220%0.20326%0.255CS..Hα-helixtrans-63.2-22.5178.181.30000113.4L428 S429 S445 F446 G447 A451L428-S449 WeakPolarHBondContact CA-OG 3.37Å; S429-S449 WeakPolarHBondContact CB-O 3.5Å; S429-S449 PolarHBondContact N-OG 3.3Å; S429-S449 VanDerWaalsContact N-OG 3.11Å; S429-S449 PolarHBondContact OG-O 2.65Å; S445-S449 PolarHBondContact O-N 2.87Å; S445-S449 VanDerWaalsContact O-N 3.09Å; F446-S449 WeakPolarHBondContact O-CB 3.08Å; F446-S449 PolarHBondContact O-N 3.36Å; F446-S449 VanDerWaalsContact O-N 3.15Å; F446-S449 PolarHBondContact O-OG 3.28Å; G447-S449 PolarHBondContact O-N 3.07Å; S449-A451 VanDerWaalsContact C-N 3.33Å
450W98.2Very high95.6Very high24 Ų2442 Ų429%0.09124%0.243CC..THydrogen-bonded Turntrans-92.416.5179.8-73.6105.7000114.1Y292 T293 V412 L414 A427 F446 G447 A448 V452Y292-W450 WeakPolarHBondContact CA-O 3.48Å; T293-W450 PolarHBondContact N-O 3.47Å; V412-W450 HydrophobicContact CB-CH2 3.72Å; V412-W450 HydrophobicContact CB-CZ2 4.44Å; V412-W450 HydrophobicContact CB-CZ3 4.41Å; V412-W450 HydrophobicContact CG2-CH2 3.97Å; V412-W450 HydrophobicContact CG2-CZ3 4.22Å; L414-W450 HydrophobicContact CD2-CB 3.85Å; L414-W450 HydrophobicContact CD2-CG 3.95Å; L414-W450 HydrophobicContact CG-CB 4.01Å; L414-W450 HydrophobicContact CG-CG 4.29Å; A427-W450 WeakPolarHBondContact O-CZ2 3.49Å; A427-W450 PolarHBondContact O-NE1 3.3Å; F446-W450 AromaticContact CE2-CD1 3.78Å; F446-W450 AromaticContact CE2-NE1 3.53Å; G447-W450 PolarHBondContact O-N 2.97Å; G447-W450 VanDerWaalsContact O-N 3.14Å; A448-W450 PolarHBondContact O-N 3.47Å; W450-V452 PolarHBondContact O-N 3.4Å
451A98.2Very high95.8Very high33 Ų3341.4 Ų41.427%0.27324%0.235SC..BIsolated β-bridgetrans-53.4134.7171.600000110.8E291 Y292 A448 S449 R475 H476E291-A451 WeakPolarHBondContact O-CA 3.29Å; Y292-A451 HydrophobicContact CD1-CB 4.41Å; Y292-A451 HydrophobicContact CE1-CB 4.39Å; A448-A451 WeakPolarHBondContact O-CB 3.22Å; A448-A451 PolarHBondContact O-N 3.09Å; S449-A451 VanDerWaalsContact C-N 3.33Å; A451-R475 HydrophobicContact CB-CB 4.35Å; A451-H476 HydrophobicContact CB-CB 3.84Å
452V97.4Very high95.9Very high6 Ų641.1 Ų41.14%0.03624%0.237CC..PPolyproline II helixtrans-64.2144.9-179.5171.40000110.2E291 Q305 W450 A457 R475E291-V452 HydrophobicContact CB-CB 4.34Å; E291-V452 HydrophobicContact CB-CG2 4.32Å; E291-V452 PolarHBondContact O-N 2.87Å; Q305-V452 HydrophobicContact CB-CG2 4.23Å; Q305-V452 HydrophobicContact CG-CG2 3.78Å; W450-V452 PolarHBondContact O-N 3.4Å; V452-A457 HydrophobicContact CG1-CB 3.83Å; V452-R475 VanDerWaalsContact O-CB 3.29Å; V452-R475 WeakPolarHBondContact O-CB 3.36Å; V452-R475 WeakPolarHBondContact O-CG 3.4Å
453E93.1Very high95.8Very high134 Ų13441 Ų4163%0.62624%0.241SC*.PPolyproline II helixtrans-83.9144.6170.4-62.2-175.7176.200110.9T455 S456 A457E453-T455 PolarHBondContact O-N 3.04Å; E453-T455 VanDerWaalsContact O-N 3.11Å; E453-S456 PolarHBondContact N-OG 2.8Å; E453-S456 PolarHBondContact O-N 3.37Å; E453-S456 PolarHBondContact O-OG 2.75Å; E453-A457 PolarHBondContact O-N 3.47Å; E453-A457 VanDerWaalsContact O-N 3.16Å
454N86.8Confident95.8Very high101 Ų10147.3 Ų47.354%0.5427%0.27SS..THydrogen-bonded Turntrans-53.9-36.1-178.1-77.4-5.2000114.3S456 R475N454-S456 VanDerWaalsContact C-N 3.3Å; N454-R475 PolarHBondContact OD1-NE 2.96Å; N454-R475 PolarHBondContact OD1-NH2 3.42Å
455T89.8Confident95.6Very high134 Ų13452.6 Ų52.682%0.82230%0.299SS*.THydrogen-bonded Turntrans-76.2-18-179.846.40000113.5E453E453-T455 PolarHBondContact O-N 3.04Å; E453-T455 VanDerWaalsContact O-N 3.11Å
456S94.3Very high95.5Very high50 Ų5050.2 Ų50.235%0.3528%0.281SS..THydrogen-bonded Turntrans-107.8-3.4-175.373.30000113.6Q305 E453 N454 L458Q305-S456 PolarHBondContact NE2-O 3.21Å; E453-S456 PolarHBondContact N-OG 2.8Å; E453-S456 PolarHBondContact O-N 3.37Å; E453-S456 PolarHBondContact O-OG 2.75Å; N454-S456 VanDerWaalsContact C-N 3.3Å; S456-L458 PolarHBondContact O-N 3.05Å
457A96.6Very high95.4Very high26 Ų2652.8 Ų52.822%0.21530%0.295CS..  trans-65.1129.3-177.500000111.5V452 E453 Y461V452-A457 HydrophobicContact CG1-CB 3.83Å; E453-A457 PolarHBondContact O-N 3.47Å; E453-A457 VanDerWaalsContact O-N 3.16Å; A457-Y461 WeakPolarHBondContact CB-OH 3.4Å
458L98.2Very high95.2Very high24 Ų2457 Ų5713%0.12632%0.317CS..  trans-94.2-5.5179.9-62.2-178.1000113.2T303 A327 K329 I335 S456T303-L458 HydrophobicContact CG2-CD1 3.9Å; A327-L458 HydrophobicContact CB-CB 3.6Å; K329-L458 HydrophobicContact CB-CD1 3.94Å; K329-L458 HydrophobicContact CB-CD2 4.31Å; K329-L458 HydrophobicContact CD-CD2 4.42Å; I335-L458 HydrophobicContact CD1-CD2 3.96Å; I335-L458 HydrophobicContact CG1-CD2 4.27Å; I335-L458 HydrophobicContact CG2-CB 4.05Å; I335-L458 WeakPolarHBondContact CG2-O 3.4Å; S456-L458 PolarHBondContact O-N 3.05Å
459F98Very high94.9Very high7 Ų758.1 Ų58.13%0.03133%0.326CS..  trans-83.6158.3-172.4-58-84.5000114E291 Q305 R307 A325 A327 E337 Y461E291-F459 HydrophobicContact CB-CD2 4.48Å; E291-F459 HydrophobicContact CB-CE2 4.01Å; E291-F459 VanDerWaalsContact CD-CD2 3.44Å; E291-F459 HydrophobicContact CG-CD2 4.08Å; E291-F459 HydrophobicContact CG-CE2 3.89Å; E291-F459 WeakPolarHBondContact OE1-CD2 3.48Å; Q305-F459 HydrophobicContact CB-CE2 3.7Å; Q305-F459 HydrophobicContact CB-CZ 3.79Å; R307-F459 HydrophobicContact CB-CE1 4.01Å; R307-F459 HydrophobicContact CB-CZ 4.03Å; A325-F459 HydrophobicContact CB-CD1 4.07Å; A325-F459 HydrophobicContact CB-CE1 3.83Å; A327-F459 HydrophobicContact CB-CD1 3.63Å; A327-F459 HydrophobicContact CB-CE1 3.63Å; A327-F459 HydrophobicContact CB-CG 4.1Å; A327-F459 HydrophobicContact CB-CZ 4.1Å; E337-F459 HydrophobicContact CG-CD1 4.29Å; F459-Y461 HydrophobicContact CB-CE1 4.3Å; F459-Y461 HydrophobicContact CB-CE2 4.4Å; F459-Y461 WeakPolarHBondContact O-CE2 3.47Å
460T97Very high94.7Very high6 Ų657 Ų574%0.03732%0.317CS..  trans-90.7137.7172.6-480000110.2E337 L349 Q352 D462E337-T460 WeakPolarHBondContact OE2-CB 3.41Å; E337-T460 PolarHBondContact OE2-N 3.13Å; E337-T460 PolarHBondContact OE2-OG1 2.68Å; L349-T460 HydrophobicContact CD2-CG2 4.06Å; Q352-T460 WeakPolarHBondContact CA-OG1 3.43Å; Q352-T460 HydrophobicContact CB-CG2 3.69Å; Q352-T460 HydrophobicContact CG-CG2 3.98Å; T460-D462 HydrophobicContact CG2-CB 3.95Å
461Y96Very high94.3Very high35 Ų3561.6 Ų61.614%0.13734%0.335CS..  trans-121.566.5177.6-50.7-80.2000109.9E291 A457 F459 S463 L466 Y471 R475E291-Y461 WeakPolarHBondContact OE1-CE1 3.47Å; E291-Y461 PolarHBondContact OE1-OH 3.01Å; E291-Y461 PolarHBondContact OE2-OH 3.47Å; A457-Y461 WeakPolarHBondContact CB-OH 3.4Å; F459-Y461 HydrophobicContact CB-CE1 4.3Å; F459-Y461 HydrophobicContact CB-CE2 4.4Å; F459-Y461 WeakPolarHBondContact O-CE2 3.47Å; Y461-S463 VanDerWaalsContact C-N 3.35Å; Y461-L466 HydrophobicContact CD1-CB 4.23Å; Y461-Y471 AromaticContact CD2-CD2 3.64Å; Y461-Y471 HydrophobicContact CD2-CD2 3.64Å; Y461-Y471 HydrophobicContact CD2-CE2 4.48Å; Y461-Y471 HydrophobicContact CD2-CG 4.42Å; Y461-Y471 HydrophobicContact CE2-CD2 4.01Å; Y461-Y471 HydrophobicContact CG-CD2 4.13Å; Y461-Y471 HydrophobicContact CG-CG 4.49Å; Y461-R475 PolarHBondContact OH-NH1 3.38Å; Y461-R475 PolarHBondContact OH-NH2 2.89Å
462D95.1Very high94.1Very high87 Ų8766.8 Ų66.847%0.46535%0.352SS..  trans-91.211.6-17359.9-17.3000114.1R339 T460 L466R339-D462 IonicContact CZ-OD1 3.96Å; R339-D462 IonicContact CZ-OD2 2.68Å; R339-D462 VanDerWaalsContact NH1-CG 3.33Å; R339-D462 IonicContact NH1-OD1 2.71Å; R339-D462 PolarHBondContact NH1-OD1 3.49Å; R339-D462 IonicContact NH1-OD2 3.29Å; R339-D462 PolarHBondContact NH1-OD2 3.01Å; R339-D462 VanDerWaalsContact NH1-OD2 3.14Å; R339-D462 IonicContact NH2-OD1 3.12Å; R339-D462 IonicContact NH2-OD2 3.96Å; R339-D462 PolarHBondContact NH2-OD2 3.32Å; T460-D462 HydrophobicContact CG2-CB 3.95Å; D462-L466 WeakPolarHBondContact OD1-CD1 3.43Å
463S94.3Very high93.7Very high45 Ų4568.4 Ų68.432%0.31537%0.366SS..SBendtrans-141.1153.917469.30000111.9Y461 N465 L466 L467Y461-S463 VanDerWaalsContact C-N 3.35Å; S463-N465 PolarHBondContact O-N 3.01Å; S463-L466 PolarHBondContact O-N 2.87Å; S463-L466 VanDerWaalsContact O-N 3.07Å; S463-L466 VanDerWaalsContact OG-CG 3.31Å; S463-L466 WeakPolarHBondContact OG-CG 3.48Å; S463-L466 PolarHBondContact OG-N 3.17Å; S463-L467 WeakPolarHBondContact O-CG 2.97Å; S463-L467 PolarHBondContact O-N 3.18Å
464E95.6Very high93.6Very high147 Ų14765.2 Ų65.269%0.68736%0.362SS*.Hα-helixtrans-56.9-36.8177.6-166.5176.5-169.700112L467 N468E464-L467 PolarHBondContact O-N 3.32Å; E464-N468 WeakPolarHBondContact O-CB 3.48Å; E464-N468 VanDerWaalsContact O-CG 3.3Å; E464-N468 PolarHBondContact O-N 3.1Å; E464-N468 PolarHBondContact O-ND2 3.4Å
465N92.1Very high93.9Very high127 Ų12761 Ų6168%0.67934%0.339SS*.Hα-helixtrans-62.4-46.8174.9-71.3-11.6000112.1S463 A469S463-N465 PolarHBondContact O-N 3.01Å; N465-A469 WeakPolarHBondContact O-CB 2.99Å; N465-A469 PolarHBondContact O-N 3.34Å
466L94.3Very high94.2Very high20 Ų2056.1 Ų56.111%0.10531%0.307CS..Hα-helixtrans-67.8-37.8179.3-70175.2000111.8Y461 D462 S463 Y470 Y471Y461-L466 HydrophobicContact CD1-CB 4.23Å; D462-L466 WeakPolarHBondContact OD1-CD1 3.43Å; S463-L466 PolarHBondContact O-N 2.87Å; S463-L466 VanDerWaalsContact O-N 3.07Å; S463-L466 VanDerWaalsContact OG-CG 3.31Å; S463-L466 WeakPolarHBondContact OG-CG 3.48Å; S463-L466 PolarHBondContact OG-N 3.17Å; L466-Y470 HydrophobicContact CD2-CD2 3.97Å; L466-Y470 HydrophobicContact CD2-CE2 3.91Å; L466-Y470 PolarHBondContact O-N 3.17Å; L466-Y471 PolarHBondContact O-N 3.3Å
467L95.2Very high94.2Very high54 Ų5455.5 Ų55.528%0.28330%0.3SS..Iπ-helixtrans-61.7-51.3175.7-74.1168.8000111.2S463 E464 Y471 F472S463-L467 WeakPolarHBondContact O-CG 2.97Å; S463-L467 PolarHBondContact O-N 3.18Å; E464-L467 PolarHBondContact O-N 3.32Å; L467-Y471 HydrophobicContact CD2-CD1 4.06Å; L467-Y471 HydrophobicContact CD2-CG 3.95Å; L467-Y471 WeakPolarHBondContact O-CA 3.3Å; L467-Y471 WeakPolarHBondContact O-CB 3.34Å; L467-Y471 PolarHBondContact O-N 3.04Å; L467-F472 HydrophobicContact CB-CD2 4.13Å; L467-F472 HydrophobicContact CB-CE2 3.82Å; L467-F472 HydrophobicContact CD2-CE2 4.43Å; L467-F472 WeakPolarHBondContact O-CD2 3.31Å; L467-F472 PolarHBondContact O-N 3.38Å
468N93.9Very high94Very high89 Ų8958.4 Ų58.448%0.47632%0.316SS..Iπ-helixtrans-69.6-36.5-178.3-69.9-24.9000112.8E464 A473E464-N468 WeakPolarHBondContact O-CB 3.48Å; E464-N468 VanDerWaalsContact O-CG 3.3Å; E464-N468 PolarHBondContact O-N 3.1Å; E464-N468 PolarHBondContact O-ND2 3.4Å; N468-A473 WeakPolarHBondContact O-CB 3.45Å
469A91Very high93.8Very high42 Ų4264 Ų6435%0.34735%0.347SS..Iπ-helixtrans-79.5-28.3-176.400000113.9N465N465-A469 WeakPolarHBondContact O-CB 2.99Å; N465-A469 PolarHBondContact O-N 3.34Å
470Y93Very high93.5Very high7 Ų764.6 Ų64.63%0.02735%0.349CS..Iπ-helixtrans-133.4-42.6-171.4-55.6-71.7000113.8E291 R307 E309 L466 R475E291-Y470 HydrophobicContact CG-CD1 3.96Å; E291-Y470 HydrophobicContact CG-CE1 4.44Å; E291-Y470 HydrophobicContact CG-CG 4.46Å; R307-Y470 HydrophobicContact CG-CE1 4.18Å; R307-Y470 HydrophobicContact CG-CE2 4.37Å; E309-Y470 WeakPolarHBondContact CG-OH 3.29Å; E309-Y470 WeakPolarHBondContact OE1-CE2 3.29Å; E309-Y470 PolarHBondContact OE1-OH 2.73Å; L466-Y470 HydrophobicContact CD2-CD2 3.97Å; L466-Y470 HydrophobicContact CD2-CE2 3.91Å; L466-Y470 PolarHBondContact O-N 3.17Å; Y470-R475 VanDerWaalsContact CB-NH1 3.33Å; Y470-R475 WeakPolarHBondContact O-CD 3.36Å; Y470-R475 PolarHBondContact O-NE 3.46Å; Y470-R475 PolarHBondContact O-NH1 2.94Å
471Y91.7Very high93.3Very high119 Ų11968.8 Ų68.847%0.46737%0.369SS..Iπ-helixtrans-72.5-45.7-175.4-172.1-92.6000112.8Y461 L466 L467Y461-Y471 AromaticContact CD2-CD2 3.64Å; Y461-Y471 HydrophobicContact CD2-CD2 3.64Å; Y461-Y471 HydrophobicContact CD2-CE2 4.48Å; Y461-Y471 HydrophobicContact CD2-CG 4.42Å; Y461-Y471 HydrophobicContact CE2-CD2 4.01Å; Y461-Y471 HydrophobicContact CG-CD2 4.13Å; Y461-Y471 HydrophobicContact CG-CG 4.49Å; L466-Y471 PolarHBondContact O-N 3.3Å; L467-Y471 HydrophobicContact CD2-CD1 4.06Å; L467-Y471 HydrophobicContact CD2-CG 3.95Å; L467-Y471 WeakPolarHBondContact O-CA 3.3Å; L467-Y471 WeakPolarHBondContact O-CB 3.34Å; L467-Y471 PolarHBondContact O-N 3.04Å
472F92.4Very high93.1Very high143 Ų14367.6 Ų67.663%0.62737%0.366SS*.SBendtrans-91.9-13.8179.3-59.8-53.5000113.7L467L467-F472 HydrophobicContact CB-CD2 4.13Å; L467-F472 HydrophobicContact CB-CE2 3.82Å; L467-F472 HydrophobicContact CD2-CE2 4.43Å; L467-F472 WeakPolarHBondContact O-CD2 3.31Å; L467-F472 PolarHBondContact O-N 3.38Å
473A90.3Very high92.8Very high39 Ų3965.5 Ų65.532%0.32236%0.356SS..SBendtrans-100.9173.1-178.500000112N468N468-A473 WeakPolarHBondContact O-CB 3.45Å
474A90.4Very high92.5Very high67 Ų6766 Ų6655%0.55435%0.353SS*.  trans-66.4141.817000000110.4H476A474-H476 WeakPolarHBondContact CB-O 3.39Å; A474-H476 PolarHBondContact O-N 2.03Å
475R93Very high91.9Very high13 Ų1363 Ų635%0.04935%0.348CS..SBendtrans-72-14.1-178.4-61.5-65.3-174.7176.1-1.2113.9G290 E291 A451 V452 N454 Y461 Y470G290-R475 CarbonylContact C-O 3.42Å; G290-R475 WeakPolarHBondContact CA-O 3.39Å; E291-R475 PolarHBondContact N-O 2.03Å; E291-R475 IonicContact OE1-NH1 3.55Å; E291-R475 WeakPolarHBondContact OE2-CD 3.26Å; E291-R475 IonicContact OE2-CZ 2.8Å; E291-R475 IonicContact OE2-NE 3.53Å; E291-R475 IonicContact OE2-NH1 3.54Å; E291-R475 PolarHBondContact OE2-NH1 2.85Å; A451-R475 HydrophobicContact CB-CB 4.35Å; V452-R475 VanDerWaalsContact O-CB 3.29Å; V452-R475 WeakPolarHBondContact O-CB 3.36Å; V452-R475 WeakPolarHBondContact O-CG 3.4Å; N454-R475 PolarHBondContact OD1-NE 2.96Å; N454-R475 PolarHBondContact OD1-NH2 3.42Å; Y461-R475 PolarHBondContact OH-NH1 3.38Å; Y461-R475 PolarHBondContact OH-NH2 2.89Å; Y470-R475 VanDerWaalsContact CB-NH1 3.33Å; Y470-R475 WeakPolarHBondContact O-CD 3.36Å; Y470-R475 PolarHBondContact O-NE 3.46Å; Y470-R475 PolarHBondContact O-NH1 2.94Å
476H95.8Very high91.5Very high31 Ų3159.3 Ų59.314%0.14433%0.33CS..BIsolated β-bridgetrans-122.5131.6163.6170.673000107.6Y292 F444 A451 A474 P478Y292-H476 HydrophobicContact CE1-CB 4.16Å; Y292-H476 AromaticContact CE1-ND1 3.83Å; Y292-H476 AromaticContact CZ-ND1 3.76Å; Y292-H476 PolarHBondContact OH-ND1 2.88Å; F444-H476 AromaticContact CE1-CE1 3.94Å; F444-H476 AromaticContact CZ-CE1 3.68Å; A451-H476 HydrophobicContact CB-CB 3.84Å; A474-H476 WeakPolarHBondContact CB-O 3.39Å; A474-H476 PolarHBondContact O-N 2.03Å; H476-P478 WeakPolarHBondContact O-CD 3.35Å
477D95.3Very high90.6Very high38 Ų3862 Ų6220%0.20335%0.349CS..  trans-85.7104.1174.1-173.8-11.4000110.1K289 N479 F480K289-D477 HydrophobicContact CB-CB 4.24Å; K289-D477 HydrophobicContact CD-CB 3.93Å; K289-D477 WeakPolarHBondContact CD-OD2 3.48Å; K289-D477 WeakPolarHBondContact CE-OD2 3.34Å; K289-D477 HydrophobicContact CG-CB 4.17Å; K289-D477 IonicContact NZ-OD2 3.27Å; K289-D477 PolarHBondContact NZ-OD2 3.38Å; K289-D477 PolarHBondContact O-N 3.4Å; D477-N479 PolarHBondContact O-N 2.96Å; D477-N479 WeakPolarHBondContact OD1-CB 3.39Å; D477-N479 PolarHBondContact OD1-N 3.41Å; D477-F480 HydrophobicContact CB-CB 4.13Å; D477-F480 PolarHBondContact O-N 3.5Å
478P91.9Very high89.7Confident87 Ų8768.9 Ų68.957%0.56538%0.379SS*.THydrogen-bonded Turntrans-70.7-12.4-177.632.3-37.7000113H476H476-P478 WeakPolarHBondContact O-CD 3.35Å
479N92.8Very high89.2Confident142 Ų14267.9 Ų67.976%0.75937%0.374SS*.THydrogen-bonded Turntrans-90-10.3178.2-57.1-59.1000112.3D477 M481D477-N479 PolarHBondContact O-N 2.96Å; D477-N479 WeakPolarHBondContact OD1-CB 3.39Å; D477-N479 PolarHBondContact OD1-N 3.41Å; N479-M481 PolarHBondContact O-N 3.34Å
480F93.3Very high88.8Confident18 Ų1871.3 Ų71.38%0.07939%0.392CS..  trans-84.4111.3175.6-177-90.1000109.8N287 K289 P310 T321 F444 D477 P482N287-F480 VanDerWaalsContact O-CE1 3.28Å; N287-F480 WeakPolarHBondContact O-CE1 3.48Å; K289-F480 HydrophobicContact CB-CB 3.89Å; K289-F480 HydrophobicContact CB-CD1 3.83Å; K289-F480 HydrophobicContact CB-CD2 4.13Å; K289-F480 HydrophobicContact CB-CE1 4.42Å; K289-F480 HydrophobicContact CB-CG 3.66Å; K289-F480 HydrophobicContact CD-CB 4.23Å; K289-F480 HydrophobicContact CD-CD2 4.14Å; K289-F480 HydrophobicContact CD-CG 4.27Å; P310-F480 HydrophobicContact CB-CE2 4.32Å; P310-F480 HydrophobicContact CG-CE2 4.12Å; T321-F480 HydrophobicContact CG2-CD1 4.3Å; T321-F480 HydrophobicContact CG2-CE1 3.47Å; T321-F480 VanDerWaalsContact CG2-CE1 3.47Å; T321-F480 HydrophobicContact CG2-CE2 4.39Å; T321-F480 HydrophobicContact CG2-CZ 3.51Å; F444-F480 WeakPolarHBondContact CZ-O 3.27Å; D477-F480 HydrophobicContact CB-CB 4.13Å; D477-F480 PolarHBondContact O-N 3.5Å; F480-P482 HydrophobicContact CE1-CB 4.11Å
481M91.4Very high88.5Confident95 Ų9577.8 Ų77.847%0.46843%0.428SS..  trans-110.7117.1175.7-69.1-59.3-61.200110.1N319 F444 N479 F484N319-M481 PolarHBondContact ND2-O 3.19Å; F444-M481 HydrophobicContact CE1-SD 4.27Å; N479-M481 PolarHBondContact O-N 3.34Å; M481-F484 HydrophobicContact CE-CE2 3.41Å; M481-F484 VanDerWaalsContact CE-CE2 3.41Å; M481-F484 HydrophobicContact CE-CZ 3.42Å; M481-F484 VanDerWaalsContact CE-CZ 3.42Å
482P92.3Very high88.3Confident9 Ų972.7 Ų72.76%0.05841%0.409CS..  trans-78.4167.2-179.133.5-36.2000112.5N287 N319 F444 F480 F484N287-P482 HydrophobicContact CB-CB 3.39Å; N287-P482 HydrophobicContact CB-CG 3.82Å; N319-P482 CarbonylContact O-C 3.55Å; N319-P482 VanDerWaalsContact O-CA 3.23Å; N319-P482 WeakPolarHBondContact O-CA 3.48Å; F444-P482 HydrophobicContact CD2-CG 3.72Å; F444-P482 VanDerWaalsContact CE2-CD 3.42Å; F444-P482 HydrophobicContact CE2-CG 3.6Å; F444-P482 HydrophobicContact CZ-CG 4.46Å; F480-P482 HydrophobicContact CE1-CB 4.11Å; P482-F484 HydrophobicContact CG-CD1 4.1Å; P482-F484 HydrophobicContact CG-CE1 3.62Å; P482-F484 HydrophobicContact CG-CZ 4.07Å; P482-F484 PolarHBondContact O-N 2.93Å; P482-F484 VanDerWaalsContact O-N 3.13Å
483V89.7Confident88.3Confident44 Ų4471.3 Ų71.327%0.26741%0.414SS..  trans-76.193171.5179.70000109.5N319 S485 P487 Y512 V516N319-V483 HydrophobicContact CB-CG2 3.95Å; N319-V483 PolarHBondContact O-N 3.1Å; V483-S485 VanDerWaalsContact CG1-O 3.23Å; V483-S485 WeakPolarHBondContact CG1-O 3.44Å; V483-S485 PolarHBondContact O-N 3.31Å; V483-S485 VanDerWaalsContact O-N 3.11Å; V483-P487 HydrophobicContact CG1-CG 4.42Å; V483-Y512 VanDerWaalsContact O-CE2 3.28Å; V483-Y512 WeakPolarHBondContact O-CE2 3.38Å; V483-Y512 PolarHBondContact O-OH 3.11Å; V483-V516 HydrophobicContact CB-CG1 3.83Å; V483-V516 HydrophobicContact CB-CG2 4.48Å; V483-V516 HydrophobicContact CG1-CG1 4.23Å; V483-V516 HydrophobicContact CG1-CG2 4.04Å; V483-V516 HydrophobicContact CG2-CG1 4.15Å
484F87.1Confident88.3Confident55 Ų5570.8 Ų70.824%0.24141%0.405CS..  trans-60.3-25.9-173.5-67-60.2000116.1P440 E441 F444 M481 P482P440-F484 HydrophobicContact CB-CB 3.85Å; P440-F484 HydrophobicContact CB-CD1 3.82Å; P440-F484 HydrophobicContact CB-CG 4.08Å; P440-F484 HydrophobicContact CG-CB 3.79Å; P440-F484 HydrophobicContact CG-CD1 4.45Å; P440-F484 HydrophobicContact CG-CG 4.24Å; E441-F484 HydrophobicContact CG-CD2 4.16Å; E441-F484 HydrophobicContact CG-CE2 3.81Å; E441-F484 HydrophobicContact CG-CZ 4.1Å; F444-F484 HydrophobicContact CB-CE1 3.7Å; F444-F484 HydrophobicContact CB-CZ 4.22Å; F444-F484 HydrophobicContact CD1-CZ 4.49Å; F444-F484 HydrophobicContact CD2-CE1 4.04Å; F444-F484 AromaticContact CG-CE1 3.89Å; F444-F484 HydrophobicContact CG-CE1 3.89Å; F444-F484 HydrophobicContact CG-CZ 4.17Å; M481-F484 HydrophobicContact CE-CE2 3.41Å; M481-F484 VanDerWaalsContact CE-CE2 3.41Å; M481-F484 HydrophobicContact CE-CZ 3.42Å; M481-F484 VanDerWaalsContact CE-CZ 3.42Å; P482-F484 HydrophobicContact CG-CD1 4.1Å; P482-F484 HydrophobicContact CG-CE1 3.62Å; P482-F484 HydrophobicContact CG-CZ 4.07Å; P482-F484 PolarHBondContact O-N 2.93Å; P482-F484 VanDerWaalsContact O-N 3.13Å
485S83.8Confident88.4Confident84 Ų8469.4 Ų69.459%0.58739%0.389SS*.SBendtrans-142.1145.3-178.759.30000110.6V483 P487V483-S485 VanDerWaalsContact CG1-O 3.23Å; V483-S485 WeakPolarHBondContact CG1-O 3.44Å; V483-S485 PolarHBondContact O-N 3.31Å; V483-S485 VanDerWaalsContact O-N 3.11Å; S485-P487 WeakPolarHBondContact O-CD 3.27Å
486V82.3Confident88.3Confident49 Ų4973.3 Ų73.330%0.29741%0.414SS..  trans-56123.7173.5-177.90000109.6E488 Y512 L515 V516V486-E488 PolarHBondContact O-N 2.64Å; V486-Y512 HydrophobicContact CG2-CD2 3.67Å; V486-Y512 HydrophobicContact CG2-CG 4.17Å; V486-L515 HydrophobicContact CG1-CB 3.71Å; V486-L515 HydrophobicContact CG1-CD1 3.52Å; V486-L515 HydrophobicContact CG1-CG 4.25Å; V486-V516 HydrophobicContact CG2-CG2 4.35Å
487P76.8Confident88.2Confident77 Ų7775.7 Ų75.750%0.543%0.426SS..  trans-61.2127.1174.7-21.632.7000110.6V483 S485 N489V483-P487 HydrophobicContact CG1-CG 4.42Å; S485-P487 WeakPolarHBondContact O-CD 3.27Å; P487-N489 PolarHBondContact O-N 3.36Å
488E75.9Confident88.1Confident199 Ų19973.9 Ų73.993%0.9342%0.416SS*.  trans-70.2101.8174.2-69-172.8174.400109.8V486V486-E488 PolarHBondContact O-N 2.64Å
489N83.6Confident88.1Confident68 Ų6872.3 Ų72.336%0.36441%0.41SS..  trans-133.7101.6172.3179.613.2000109.3P487 D491 D492 N495P487-N489 PolarHBondContact O-N 3.36Å; N489-D491 PolarHBondContact O-N 3.46Å; N489-D491 PolarHBondContact OD1-N 3.07Å; N489-D491 VanDerWaalsContact OD1-N 3.13Å; N489-D492 HydrophobicContact CB-CB 4.18Å; N489-D492 WeakPolarHBondContact O-CB 3.26Å; N489-D492 PolarHBondContact O-N 3.49Å; N489-D492 VanDerWaalsContact O-N 3.12Å; N489-N495 PolarHBondContact O-ND2 2.89Å
490P81.4Confident88.2Confident113 Ų11372.1 Ų72.173%0.73440%0.404SS*.THydrogen-bonded Turntrans-58.6-31.2178.4-2434.1000113.2D492 N495P490-D492 VanDerWaalsContact C-N 3.28Å; P490-D492 PolarHBondContact O-N 3.13Å; P490-N495 PolarHBondContact O-ND2 3.43Å
491D88.2Confident88.2Confident144 Ų14472.7 Ų72.777%0.7741%0.408SS*.THydrogen-bonded Turntrans-88.710.6-178.5-59.1-43.4000112.8N489 P493N489-D491 PolarHBondContact O-N 3.46Å; N489-D491 PolarHBondContact OD1-N 3.07Å; N489-D491 VanDerWaalsContact OD1-N 3.13Å; D491-P493 WeakPolarHBondContact O-CD 3.49Å
492D87.4Confident88.4Confident12 Ų1268.6 Ų68.66%0.06439%0.389CS..  trans-62.8122.1176.3-160.8-60.2000110.1N489 P490 L494 N495 R518N489-D492 HydrophobicContact CB-CB 4.18Å; N489-D492 WeakPolarHBondContact O-CB 3.26Å; N489-D492 PolarHBondContact O-N 3.49Å; N489-D492 VanDerWaalsContact O-N 3.12Å; P490-D492 VanDerWaalsContact C-N 3.28Å; P490-D492 PolarHBondContact O-N 3.13Å; D492-L494 PolarHBondContact O-N 3.06Å; D492-L494 PolarHBondContact OD1-N 2.57Å; D492-N495 WeakPolarHBondContact O-CB 3.04Å; D492-N495 PolarHBondContact O-N 3.43Å; D492-R518 IonicContact OD1-NH1 3.98Å; D492-R518 PolarHBondContact OD1-NH1 2.88Å; D492-R518 IonicContact OD2-CZ 3.6Å; D492-R518 VanDerWaalsContact OD2-CZ 3.23Å; D492-R518 IonicContact OD2-NH1 2.99Å; D492-R518 PolarHBondContact OD2-NH1 3.09Å; D492-R518 IonicContact OD2-NH2 2.86Å; D492-R518 PolarHBondContact OD2-NH2 3.27Å
493P90.7Very high88.3Confident113 Ų11371.9 Ų71.973%0.73441%0.409SS*.THydrogen-bonded Turntrans-62.5-19-175.625.6-35.6000113.1D491D491-P493 WeakPolarHBondContact O-CD 3.49Å
494L92.1Very high88.4Confident28 Ų2872.5 Ų72.515%0.14742%0.424CS..THydrogen-bonded Turntrans-88.1-6.8178.9-63.1179.6000113.6D492 T496 Q497 A498 I514 L515 R518 P520D492-L494 PolarHBondContact O-N 3.06Å; D492-L494 PolarHBondContact OD1-N 2.57Å; L494-T496 PolarHBondContact O-N 3.01Å; L494-Q497 PolarHBondContact O-N 3.35Å; L494-A498 VanDerWaalsContact O-CB 3.3Å; L494-A498 WeakPolarHBondContact O-CB 3.44Å; L494-A498 PolarHBondContact O-N 3.06Å; L494-I514 HydrophobicContact CB-CG2 4.04Å; L494-I514 HydrophobicContact CD1-CG2 4.22Å; L494-I514 WeakPolarHBondContact CD1-O 3.36Å; L494-L515 HydrophobicContact CB-CD2 3.89Å; L494-R518 HydrophobicContact CD1-CB 4.46Å; L494-P520 HydrophobicContact CD2-CG 4.34Å
495N91.2Very high88.5Confident38 Ų3877.2 Ų77.220%0.20345%0.447CS..Hα-helixtrans-58.4-46.4-176.5-85.6-27.6000113.4N489 P490 D492 A498 A499N489-N495 PolarHBondContact O-ND2 2.89Å; P490-N495 PolarHBondContact O-ND2 3.43Å; D492-N495 WeakPolarHBondContact O-CB 3.04Å; D492-N495 PolarHBondContact O-N 3.43Å; N495-A498 PolarHBondContact O-N 3.32Å; N495-A499 WeakPolarHBondContact O-CB 3.34Å; N495-A499 PolarHBondContact O-N 2.83Å
496T91.3Very high88.8Confident96 Ų9673.4 Ų73.459%0.58942%0.421SS*.Hα-helixtrans-62.3-48.3179.4-54.30000110.5L494 A498 A499 E500L494-T496 PolarHBondContact O-N 3.01Å; T496-A498 VanDerWaalsContact C-N 3.33Å; T496-A498 PolarHBondContact O-N 3.33Å; T496-A499 PolarHBondContact O-N 3.42Å; T496-A499 VanDerWaalsContact O-N 3.16Å; T496-E500 WeakPolarHBondContact O-CG 3.41Å; T496-E500 PolarHBondContact O-N 3.27Å
497Q93.2Very high89.3Confident81 Ų8172.7 Ų72.738%0.37942%0.418SS..Hα-helixtrans-65.2-37.5-179.9-166.1170.836.600112L494 E500 I501 P520L494-Q497 PolarHBondContact O-N 3.35Å; Q497-E500 PolarHBondContact O-N 3.47Å; Q497-I501 HydrophobicContact CG-CD1 3.77Å; Q497-I501 HydrophobicContact CG-CG1 4.42Å; Q497-I501 WeakPolarHBondContact O-CB 3.11Å; Q497-I501 WeakPolarHBondContact O-CG1 3.42Å; Q497-I501 PolarHBondContact O-N 3.12Å; Q497-P520 VanDerWaalsContact CD-CG 3.45Å; Q497-P520 HydrophobicContact CG-CB 4.31Å; Q497-P520 HydrophobicContact CG-CG 4.35Å
498A92.9Very high90Very high0 Ų074 Ų740%042%0.418CS..Hα-helixtrans-64.5-38.9174.100000112.1L494 N495 T496 C502 I514 L515L494-A498 VanDerWaalsContact O-CB 3.3Å; L494-A498 WeakPolarHBondContact O-CB 3.44Å; L494-A498 PolarHBondContact O-N 3.06Å; N495-A498 PolarHBondContact O-N 3.32Å; T496-A498 VanDerWaalsContact C-N 3.33Å; T496-A498 PolarHBondContact O-N 3.33Å; A498-C502 WeakPolarHBondContact O-CB 3.28Å; A498-C502 PolarHBondContact O-N 3.47Å; A498-C502 PolarHBondContact O-SG 2.89Å; A498-C502 VanDerWaalsContact O-SG 3.38Å; A498-I514 HydrophobicContact CB-CB 4.21Å; A498-I514 HydrophobicContact CB-CD1 4.12Å; A498-I514 HydrophobicContact CB-CG2 3.97Å; A498-L515 HydrophobicContact CB-CD2 4.36Å; A498-L515 HydrophobicContact CB-CG 4.4Å
499A92.4Very high90.9Very high53 Ų5365.2 Ų65.244%0.43838%0.376SS..Hα-helixtrans-68-35175.600000112.8N495 T496N495-A499 WeakPolarHBondContact O-CB 3.34Å; N495-A499 PolarHBondContact O-N 2.83Å; T496-A499 PolarHBondContact O-N 3.42Å; T496-A499 VanDerWaalsContact O-N 3.16Å
500E94.4Very high91.4Very high138 Ų13862 Ų6265%0.64536%0.359SS*.Hα-helixtrans-72.4-43.1177.4-72.1174179.900112.6T496 Q497T496-E500 WeakPolarHBondContact O-CG 3.41Å; T496-E500 PolarHBondContact O-N 3.27Å; Q497-E500 PolarHBondContact O-N 3.47Å
501I94.6Very high91.9Very high31 Ų3160.7 Ų60.716%0.15934%0.34CS..Hα-helixtrans-77.7-48.1-177.8-64.7173.1000110.7Q497 T503 I514 P520 N524 R527Q497-I501 HydrophobicContact CG-CD1 3.77Å; Q497-I501 HydrophobicContact CG-CG1 4.42Å; Q497-I501 WeakPolarHBondContact O-CB 3.11Å; Q497-I501 WeakPolarHBondContact O-CG1 3.42Å; Q497-I501 PolarHBondContact O-N 3.12Å; I501-T503 PolarHBondContact O-N 3.36Å; I501-I514 HydrophobicContact CB-CD1 4.17Å; I501-I514 HydrophobicContact CD1-CD1 4.19Å; I501-I514 HydrophobicContact CG2-CD1 4.25Å; I501-P520 HydrophobicContact CD1-CB 3.82Å; I501-N524 HydrophobicContact CG2-CB 3.91Å; I501-R527 WeakPolarHBondContact O-CD 3.39Å; I501-R527 PolarHBondContact O-NH1 3Å
502C94.7Very high92.1Very high8 Ų855 Ų555%0.05431%0.307CS..  trans-91.790.2-169.7-51.40000111.3A498 C510 R511 I514A498-C502 WeakPolarHBondContact O-CB 3.28Å; A498-C502 PolarHBondContact O-N 3.47Å; A498-C502 PolarHBondContact O-SG 2.89Å; A498-C502 VanDerWaalsContact O-SG 3.38Å; C502-C510 WeakPolarHBondContact CA-SG 3.06Å; C502-C510 HydrophobicContact CB-CB 3.6Å; C502-C510 WeakPolarHBondContact CB-SG 3.49Å; C502-C510 WeakPolarHBondContact SG-CB 3.35Å; C502-C510 PolarHBondContact SG-O 2.7Å; C502-C510 CovalentContact SG-SG 2.03Å; C502-C510 PolarHBondContact SG-SG 3.26Å; C502-R511 HydrophobicContact CB-CG 3.58Å; C502-R511 PolarHBondContact SG-N 3.32Å; C502-I514 VanDerWaalsContact SG-CD1 3.51Å
503T90.9Very high92.3Very high78 Ų7854.4 Ų54.448%0.47930%0.304SS..  trans-121.5152.6179.257.70000111.3I501I501-T503 PolarHBondContact O-N 3.36Å
504G91.3Very high92.3Very high58 Ų5849 Ų4960%0.59827%0.269SS*.SBendtrans81.4-163.5177.900000114.8S507G504-S507 WeakPolarHBondContact O-CB 3.22Å; G504-S507 PolarHBondContact O-N 3Å; G504-S507 PolarHBondContact O-OG 3.19Å
505E90.4Very high92.2Very high154 Ų15448 Ų4872%0.7226%0.264SS*.THydrogen-bonded Turntrans-63.9142.5175.3-165.8-179.9-176.700110.7S507 F530E505-S507 PolarHBondContact O-N 2.88Å; E505-F530 VanDerWaalsContact C-CE1 3.45Å; E505-F530 HydrophobicContact CB-CE1 4.05Å; E505-F530 HydrophobicContact CB-CZ 4.4Å; E505-F530 HydrophobicContact CG-CE1 4.01Å; E505-F530 HydrophobicContact CG-CZ 3.85Å; E505-F530 WeakPolarHBondContact O-CD1 3Å; E505-F530 WeakPolarHBondContact O-CE1 3.47Å
506G89.3Confident92.1Very high4 Ų446.7 Ų46.74%0.04126%0.258CS..THydrogen-bonded Turntrans76.63.2-175.800000114.3Q508 F509G506-Q508 VanDerWaalsContact C-OE1 3.22Å; G506-Q508 VanDerWaalsContact CA-OE1 3.3Å; G506-Q508 PolarHBondContact O-N 3.47Å; G506-F509 WeakPolarHBondContact O-CB 3.32Å; G506-F509 PolarHBondContact O-N 3.4Å; G506-F509 VanDerWaalsContact O-N 3.11Å
507S92.8Very high91.8Very high34 Ų3442.3 Ų42.324%0.23823%0.232CC..Hα-helixtrans-59-27.7179.154.50000113.4G504 E505 F509 C510 R511G504-S507 WeakPolarHBondContact O-CB 3.22Å; G504-S507 PolarHBondContact O-N 3Å; G504-S507 PolarHBondContact O-OG 3.19Å; E505-S507 PolarHBondContact O-N 2.88Å; S507-F509 VanDerWaalsContact C-N 3.31Å; S507-F509 PolarHBondContact O-N 2.97Å; S507-C510 PolarHBondContact O-N 3.13Å; S507-R511 WeakPolarHBondContact O-CB 3.19Å; S507-R511 VanDerWaalsContact O-CG 3.25Å; S507-R511 WeakPolarHBondContact O-CG 3.36Å; S507-R511 PolarHBondContact O-N 3.1Å
508Q91.8Very high91.6Very high105 Ų10543.4 Ų43.449%0.49123%0.232SC..Hα-helixtrans-60.1-39175.570.5-75.21.300112.9G506 Y512G506-Q508 VanDerWaalsContact C-OE1 3.22Å; G506-Q508 VanDerWaalsContact CA-OE1 3.3Å; G506-Q508 PolarHBondContact O-N 3.47Å; Q508-Y512 WeakPolarHBondContact O-CB 3.42Å; Q508-Y512 PolarHBondContact O-N 3.46Å; Q508-Y512 VanDerWaalsContact O-N 3.08Å
509F93.8Very high91.4Very high14 Ų1444.2 Ų44.26%0.06124%0.238CC..Hα-helixtrans-65.4-55.3176.7-62.2-49.6000109.9F271 H275 G506 S507 R511 Y512 D513 T526 F530F271-F509 HydrophobicContact CE2-CB 4.27Å; F271-F509 HydrophobicContact CE2-CD2 4.13Å; F271-F509 HydrophobicContact CE2-CG 4.27Å; F271-F509 AromaticContact CZ-CD2 3.89Å; F271-F509 HydrophobicContact CZ-CD2 3.89Å; F271-F509 HydrophobicContact CZ-CE2 4.16Å; F271-F509 HydrophobicContact CZ-CG 4.27Å; H275-F509 HydrophobicContact CB-CD1 3.98Å; H275-F509 HydrophobicContact CB-CE1 4.2Å; H275-F509 HydrophobicContact CB-CG 4.44Å; H275-F509 VanDerWaalsContact CD2-CB 3.47Å; H275-F509 WeakPolarHBondContact CD2-CB 3.42Å; H275-F509 AromaticContact CD2-CD1 3.68Å; H275-F509 AromaticContact CD2-CG 3.78Å; H275-F509 AromaticContact CE1-CD1 3.72Å; H275-F509 AromaticContact CG-CD1 3.42Å; H275-F509 VanDerWaalsContact CG-CD1 3.42Å; H275-F509 AromaticContact CG-CG 3.93Å; H275-F509 AromaticContact ND1-CD1 3.45Å; H275-F509 WeakPolarHBondContact ND1-CD1 3.38Å; H275-F509 WeakPolarHBondContact NE2-CB 3.41Å; H275-F509 AromaticContact NE2-CD1 3.78Å; H275-F509 AromaticContact NE2-CG 4Å; G506-F509 WeakPolarHBondContact O-CB 3.32Å; G506-F509 PolarHBondContact O-N 3.4Å; G506-F509 VanDerWaalsContact O-N 3.11Å; S507-F509 VanDerWaalsContact C-N 3.31Å; S507-F509 PolarHBondContact O-N 2.97Å; F509-R511 VanDerWaalsContact C-N 3.3Å; F509-R511 PolarHBondContact O-N 3.45Å; F509-Y512 WeakPolarHBondContact O-CB 3.41Å; F509-Y512 PolarHBondContact O-N 2.04Å; F509-Y512 VanDerWaalsContact O-N 3.12Å; F509-D513 PolarHBondContact O-N 3.44Å; F509-D513 VanDerWaalsContact O-N 3.08Å; F509-D513 VanDerWaalsContact O-OD1 3.06Å; F509-T526 HydrophobicContact CB-CG2 3.88Å; F509-F530 HydrophobicContact CD2-CD2 4.05Å; F509-F530 HydrophobicContact CD2-CE2 4.31Å; F509-F530 HydrophobicContact CE2-CD2 4.19Å; F509-F530 HydrophobicContact CE2-CE2 4.08Å
510C94.1Very high91.3Very high1 Ų143.1 Ų43.11%0.00723%0.226CC..Hα-helixtrans-54-44.1176.6173.70000112.8C502 S507 D513 I514 G523 R527C502-C510 WeakPolarHBondContact CA-SG 3.06Å; C502-C510 HydrophobicContact CB-CB 3.6Å; C502-C510 WeakPolarHBondContact CB-SG 3.49Å; C502-C510 WeakPolarHBondContact SG-CB 3.35Å; C502-C510 PolarHBondContact SG-O 2.7Å; C502-C510 CovalentContact SG-SG 2.03Å; C502-C510 PolarHBondContact SG-SG 3.26Å; S507-C510 PolarHBondContact O-N 3.13Å; C510-D513 PolarHBondContact O-N 3.26Å; C510-I514 WeakPolarHBondContact O-CG1 3.16Å; C510-I514 PolarHBondContact O-N 3.37Å; C510-I514 VanDerWaalsContact O-N 3.17Å; C510-G523 PolarHBondContact SG-O 2.03Å; C510-R527 HydrophobicContact CB-CB 4.19Å
511R93.1Very high91.2Very high85 Ų8542 Ų4232%0.32122%0.224SC..Hα-helixtrans-65.4-41.5-179.6-75178.169.679.94111.6C502 S507 F509 I514 L515C502-R511 HydrophobicContact CB-CG 3.58Å; C502-R511 PolarHBondContact SG-N 3.32Å; S507-R511 WeakPolarHBondContact O-CB 3.19Å; S507-R511 VanDerWaalsContact O-CG 3.25Å; S507-R511 WeakPolarHBondContact O-CG 3.36Å; S507-R511 PolarHBondContact O-N 3.1Å; F509-R511 VanDerWaalsContact C-N 3.3Å; F509-R511 PolarHBondContact O-N 3.45Å; R511-I514 PolarHBondContact O-N 2.88Å; R511-L515 WeakPolarHBondContact O-CB 3.4Å; R511-L515 VanDerWaalsContact O-CG 3.32Å; R511-L515 WeakPolarHBondContact O-CG 3.39Å; R511-L515 PolarHBondContact O-N 3.5Å
512Y91.3Very high91Very high23 Ų2340.8 Ų40.89%0.0922%0.218CC..Hα-helixtrans-58.4-50.6176.5178.3-82000110.5D273 N287 V483 V486 Q508 F509 I514 L515 V516D273-Y512 VanDerWaalsContact OD1-CD1 3.3Å; D273-Y512 WeakPolarHBondContact OD1-CD1 3.36Å; D273-Y512 VanDerWaalsContact OD1-CE1 3.23Å; D273-Y512 WeakPolarHBondContact OD1-CE1 3.42Å; D273-Y512 WeakPolarHBondContact OD2-CD1 3.12Å; D273-Y512 WeakPolarHBondContact OD2-CE1 3.29Å; N287-Y512 PolarHBondContact ND2-OH 3.29Å; V483-Y512 VanDerWaalsContact O-CE2 3.28Å; V483-Y512 WeakPolarHBondContact O-CE2 3.38Å; V483-Y512 PolarHBondContact O-OH 3.11Å; V486-Y512 HydrophobicContact CG2-CD2 3.67Å; V486-Y512 HydrophobicContact CG2-CG 4.17Å; Q508-Y512 WeakPolarHBondContact O-CB 3.42Å; Q508-Y512 PolarHBondContact O-N 3.46Å; Q508-Y512 VanDerWaalsContact O-N 3.08Å; F509-Y512 WeakPolarHBondContact O-CB 3.41Å; F509-Y512 PolarHBondContact O-N 2.04Å; F509-Y512 VanDerWaalsContact O-N 3.12Å; Y512-I514 VanDerWaalsContact C-N 3.3Å; Y512-I514 PolarHBondContact O-N 2.91Å; Y512-L515 PolarHBondContact O-N 2.94Å; Y512-L515 VanDerWaalsContact O-N 3.17Å; Y512-V516 HydrophobicContact CD1-CB 4.37Å; Y512-V516 HydrophobicContact CD1-CG2 4.33Å; Y512-V516 HydrophobicContact CD2-CG2 3.89Å; Y512-V516 HydrophobicContact CE1-CB 4.13Å; Y512-V516 HydrophobicContact CE1-CG1 4.28Å; Y512-V516 HydrophobicContact CE1-CG2 4.19Å; Y512-V516 HydrophobicContact CE2-CG2 3.76Å; Y512-V516 HydrophobicContact CG-CG2 4.18Å; Y512-V516 WeakPolarHBondContact O-CB 3.39Å; Y512-V516 PolarHBondContact O-N 3.25Å
513D91.4Very high90.9Very high0 Ų040.4 Ų40.40%022%0.215CC..Hα-helixtrans-61.4-34.6-178.8-70.730.7000113.5G272 D273 H275 F509 C510 G517 I522 T526G272-D513 WeakPolarHBondContact CA-OD2 3.14Å; D273-D513 PolarHBondContact N-OD2 3.48Å; H275-D513 IonicContact CD2-OD1 2.92Å; H275-D513 IonicContact CE1-OD1 2.73Å; H275-D513 IonicContact NE2-OD1 3.44Å; H275-D513 PolarHBondContact NE2-OD1 3.31Å; H275-D513 IonicContact NE2-OD2 2.67Å; F509-D513 PolarHBondContact O-N 3.44Å; F509-D513 VanDerWaalsContact O-N 3.08Å; F509-D513 VanDerWaalsContact O-OD1 3.06Å; C510-D513 PolarHBondContact O-N 3.26Å; D513-G517 WeakPolarHBondContact O-CA 3.49Å; D513-G517 PolarHBondContact O-N 2.76Å; D513-I522 HydrophobicContact CB-CG2 3.83Å; D513-T526 WeakPolarHBondContact OD2-CB 3.45Å; D513-T526 WeakPolarHBondContact OD2-CG2 3.4Å; D513-T526 PolarHBondContact OD2-OG1 2.9Å
514I91.9Very high91.1Very high0 Ų039.4 Ų39.40%021%0.207CC..Hα-helixtrans-71-48.3175.8-63.6-178.9000110.7L494 A498 I501 C502 C510 R511 Y512 R518 S519L494-I514 HydrophobicContact CB-CG2 4.04Å; L494-I514 HydrophobicContact CD1-CG2 4.22Å; L494-I514 WeakPolarHBondContact CD1-O 3.36Å; A498-I514 HydrophobicContact CB-CB 4.21Å; A498-I514 HydrophobicContact CB-CD1 4.12Å; A498-I514 HydrophobicContact CB-CG2 3.97Å; I501-I514 HydrophobicContact CB-CD1 4.17Å; I501-I514 HydrophobicContact CD1-CD1 4.19Å; I501-I514 HydrophobicContact CG2-CD1 4.25Å; C502-I514 VanDerWaalsContact SG-CD1 3.51Å; C510-I514 WeakPolarHBondContact O-CG1 3.16Å; C510-I514 PolarHBondContact O-N 3.37Å; C510-I514 VanDerWaalsContact O-N 3.17Å; R511-I514 PolarHBondContact O-N 2.88Å; Y512-I514 VanDerWaalsContact C-N 3.3Å; Y512-I514 PolarHBondContact O-N 2.91Å; I514-R518 WeakPolarHBondContact O-CA 3.34Å; I514-R518 PolarHBondContact O-N 2.83Å; I514-S519 PolarHBondContact O-N 2.87Å
515L90.4Very high91.2Very high8 Ų837 Ų374%0.04218%0.181CC..Hα-helixtrans-80.8-35-169.6-64.2173.9000112.4V486 L494 A498 R511 Y512 R518V486-L515 HydrophobicContact CG1-CB 3.71Å; V486-L515 HydrophobicContact CG1-CD1 3.52Å; V486-L515 HydrophobicContact CG1-CG 4.25Å; L494-L515 HydrophobicContact CB-CD2 3.89Å; A498-L515 HydrophobicContact CB-CD2 4.36Å; A498-L515 HydrophobicContact CB-CG 4.4Å; R511-L515 WeakPolarHBondContact O-CB 3.4Å; R511-L515 VanDerWaalsContact O-CG 3.32Å; R511-L515 WeakPolarHBondContact O-CG 3.39Å; R511-L515 PolarHBondContact O-N 3.5Å; Y512-L515 PolarHBondContact O-N 2.94Å; Y512-L515 VanDerWaalsContact O-N 3.17Å; L515-R518 WeakPolarHBondContact O-CD 3.23Å; L515-R518 PolarHBondContact O-NE 3.39Å
516V88.1Confident91.5Very high10 Ų1029.7 Ų29.76%0.06115%0.147CC..THydrogen-bonded Turntrans-86.3-51.4176.3179.10000110.6I318 A320 V483 V486 Y512 R518I318-V516 HydrophobicContact CG2-CG1 4.42Å; I318-V516 WeakPolarHBondContact CG2-O 3.46Å; A320-V516 HydrophobicContact CB-CG1 4.05Å; V483-V516 HydrophobicContact CB-CG1 3.83Å; V483-V516 HydrophobicContact CB-CG2 4.48Å; V483-V516 HydrophobicContact CG1-CG1 4.23Å; V483-V516 HydrophobicContact CG1-CG2 4.04Å; V483-V516 HydrophobicContact CG2-CG1 4.15Å; V486-V516 HydrophobicContact CG2-CG2 4.35Å; Y512-V516 HydrophobicContact CD1-CB 4.37Å; Y512-V516 HydrophobicContact CD1-CG2 4.33Å; Y512-V516 HydrophobicContact CD2-CG2 3.89Å; Y512-V516 HydrophobicContact CE1-CB 4.13Å; Y512-V516 HydrophobicContact CE1-CG1 4.28Å; Y512-V516 HydrophobicContact CE1-CG2 4.19Å; Y512-V516 HydrophobicContact CE2-CG2 3.76Å; Y512-V516 HydrophobicContact CG-CG2 4.18Å; Y512-V516 WeakPolarHBondContact O-CB 3.39Å; Y512-V516 PolarHBondContact O-N 3.25Å; V516-R518 PolarHBondContact O-N 2.92Å
517G86Confident91.8Very high4 Ų432.7 Ų32.74%0.04116%0.157CC..THydrogen-bonded Turntrans-73.9-6.7179.100000114.5I318 D513 S519I318-G517 WeakPolarHBondContact CD1-O 3.04Å; D513-G517 WeakPolarHBondContact O-CA 3.49Å; D513-G517 PolarHBondContact O-N 2.76Å; G517-S519 PolarHBondContact O-N 2.99Å; G517-S519 VanDerWaalsContact O-N 3.12Å
518R87.4Confident91.9Very high103 Ų10333.3 Ų33.339%0.38916%0.16SC..  trans54.727.3179-59.6-59.2-172.8172.9-9.3114I318 D492 L494 I514 L515 V516I318-R518 HydrophobicContact CD1-CB 4.36Å; I318-R518 HydrophobicContact CD1-CG 4.43Å; D492-R518 IonicContact OD1-NH1 3.98Å; D492-R518 PolarHBondContact OD1-NH1 2.88Å; D492-R518 IonicContact OD2-CZ 3.6Å; D492-R518 VanDerWaalsContact OD2-CZ 3.23Å; D492-R518 IonicContact OD2-NH1 2.99Å; D492-R518 PolarHBondContact OD2-NH1 3.09Å; D492-R518 IonicContact OD2-NH2 2.86Å; D492-R518 PolarHBondContact OD2-NH2 3.27Å; L494-R518 HydrophobicContact CD1-CB 4.46Å; I514-R518 WeakPolarHBondContact O-CA 3.34Å; I514-R518 PolarHBondContact O-N 2.83Å; L515-R518 WeakPolarHBondContact O-CD 3.23Å; L515-R518 PolarHBondContact O-NE 3.39Å; V516-R518 PolarHBondContact O-N 2.92Å
519S89.3Confident92.2Very high18 Ų1828.5 Ų28.513%0.12614%0.137CC..  trans-136.9110.5-174.3-178.10000112.5I514 G517 L521 I522 G523I514-S519 PolarHBondContact O-N 2.87Å; G517-S519 PolarHBondContact O-N 2.99Å; G517-S519 VanDerWaalsContact O-N 3.12Å; S519-L521 PolarHBondContact O-N 2.88Å; S519-L521 PolarHBondContact OG-N 3.31Å; S519-I522 PolarHBondContact O-N 3.49Å; S519-I522 PolarHBondContact OG-N 3.21Å; S519-G523 PolarHBondContact O-N 3.13Å
520P91.4Very high92.3Very high29 Ų2928.5 Ų28.519%0.18814%0.137CC..Hα-helixtrans-59.2-28.5171.9-23.734.4000113.1L494 Q497 I501 N524L494-P520 HydrophobicContact CD2-CG 4.34Å; Q497-P520 VanDerWaalsContact CD-CG 3.45Å; Q497-P520 HydrophobicContact CG-CB 4.31Å; Q497-P520 HydrophobicContact CG-CG 4.35Å; I501-P520 HydrophobicContact CD1-CB 3.82Å; P520-N524 WeakPolarHBondContact O-CB 3.32Å; P520-N524 PolarHBondContact O-N 3.22Å
521L90.6Very high92.5Very high115 Ų11533 Ų3360%0.60216%0.159SC*.Hα-helixtrans-68.9-42.3178.3-65176.7000111.6S519 A525S519-L521 PolarHBondContact O-N 2.88Å; S519-L521 PolarHBondContact OG-N 3.31Å; L521-A525 WeakPolarHBondContact O-CB 3.37Å; L521-A525 PolarHBondContact O-N 2.89Å
522I90.8Very high92.7Very high5 Ų531.8 Ų31.83%0.02616%0.163CC..Hα-helixtrans-63-51.7175.9-64.5178.8000109.2V311 E395 T396 D513 S519 N524 A525 T526V311-I522 HydrophobicContact CG1-CD1 4.22Å; E395-I522 HydrophobicContact CB-CG1 4.48Å; T396-I522 HydrophobicContact CG2-CB 4.26Å; T396-I522 HydrophobicContact CG2-CG1 4.26Å; T396-I522 HydrophobicContact CG2-CG2 3.64Å; D513-I522 HydrophobicContact CB-CG2 3.83Å; S519-I522 PolarHBondContact O-N 3.49Å; S519-I522 PolarHBondContact OG-N 3.21Å; I522-N524 PolarHBondContact O-N 2.94Å; I522-A525 WeakPolarHBondContact O-CA 3.36Å; I522-A525 WeakPolarHBondContact O-CB 3.48Å; I522-A525 PolarHBondContact O-N 3.19Å; I522-T526 PolarHBondContact O-N 3.34Å; I522-T526 PolarHBondContact O-OG1 2.92Å; I522-T526 VanDerWaalsContact O-OG1 3.12Å
523G92.9Very high93Very high0 Ų031.2 Ų31.20%016%0.161CC..Hα-helixtrans-60.1-40.6179.500000114.5C510 S519 A525 T526 R527C510-G523 PolarHBondContact SG-O 2.03Å; S519-G523 PolarHBondContact O-N 3.13Å; G523-A525 VanDerWaalsContact C-N 3.32Å; G523-A525 PolarHBondContact O-N 2.81Å; G523-T526 WeakPolarHBondContact O-CB 3.48Å; G523-T526 PolarHBondContact O-N 3.3Å; G523-R527 PolarHBondContact O-N 3.01Å
524N94.3Very high93.3Very high57 Ų5734.1 Ų34.131%0.30518%0.179SC..Hα-helixtrans-62.8-39.8174.2-175.341.5000111.9I501 P520 I522 T526 R527 V528I501-N524 HydrophobicContact CG2-CB 3.91Å; P520-N524 WeakPolarHBondContact O-CB 3.32Å; P520-N524 PolarHBondContact O-N 3.22Å; I522-N524 PolarHBondContact O-N 2.94Å; N524-T526 VanDerWaalsContact C-N 3.33Å; N524-R527 PolarHBondContact O-N 3.06Å; N524-R527 PolarHBondContact OD1-NE 2.98Å; N524-R527 PolarHBondContact OD1-NH2 3.34Å; N524-V528 WeakPolarHBondContact O-CG2 3.39Å; N524-V528 PolarHBondContact O-N 2.94Å
525A94.4Very high93.6Very high7 Ų737.1 Ų37.16%0.05820%0.2CC..Hα-helixtrans-64.2-37.9175.300000112.3R393 T396 L521 I522 G523 V528 S529R393-A525 HydrophobicContact CB-CB 3.82Å; R393-A525 VanDerWaalsContact O-CB 3.22Å; R393-A525 WeakPolarHBondContact O-CB 3.27Å; T396-A525 HydrophobicContact CG2-CB 4.44Å; T396-A525 WeakPolarHBondContact OG1-CB 3.44Å; L521-A525 WeakPolarHBondContact O-CB 3.37Å; L521-A525 PolarHBondContact O-N 2.89Å; I522-A525 WeakPolarHBondContact O-CA 3.36Å; I522-A525 WeakPolarHBondContact O-CB 3.48Å; I522-A525 PolarHBondContact O-N 3.19Å; G523-A525 VanDerWaalsContact C-N 3.32Å; G523-A525 PolarHBondContact O-N 2.81Å; A525-V528 PolarHBondContact O-N 3.37Å; A525-S529 WeakPolarHBondContact O-CB 3.26Å; A525-S529 PolarHBondContact O-N 2.95Å; A525-S529 PolarHBondContact O-OG 3.29Å
526T95.6Very high94Very high1 Ų137.7 Ų37.71%0.00620%0.203CC..Hα-helixtrans-63.8-46.1174.8-610000111.6F271 G272 F509 D513 I522 G523 N524 V528 S529 F530F271-T526 HydrophobicContact CD2-CG2 3.82Å; F271-T526 HydrophobicContact CE2-CG2 3.89Å; G272-T526 WeakPolarHBondContact CA-OG1 3.34Å; F509-T526 HydrophobicContact CB-CG2 3.88Å; D513-T526 WeakPolarHBondContact OD2-CB 3.45Å; D513-T526 WeakPolarHBondContact OD2-CG2 3.4Å; D513-T526 PolarHBondContact OD2-OG1 2.9Å; I522-T526 PolarHBondContact O-N 3.34Å; I522-T526 PolarHBondContact O-OG1 2.92Å; I522-T526 VanDerWaalsContact O-OG1 3.12Å; G523-T526 WeakPolarHBondContact O-CB 3.48Å; G523-T526 PolarHBondContact O-N 3.3Å; N524-T526 VanDerWaalsContact C-N 3.33Å; T526-V528 PolarHBondContact O-N 3.46Å; T526-S529 PolarHBondContact O-N 3.2Å; T526-F530 WeakPolarHBondContact O-CB 3.35Å; T526-F530 PolarHBondContact O-N 3.48Å
527R95.6Very high94.4Very high67 Ų6740.2 Ų40.225%0.25322%0.218SC..Hα-helixtrans-57.4-49.4173.2-178.9-175.269.3161.15.6112.1I501 C510 G523 N524 S529 F530 Q531I501-R527 WeakPolarHBondContact O-CD 3.39Å; I501-R527 PolarHBondContact O-NH1 3Å; C510-R527 HydrophobicContact CB-CB 4.19Å; G523-R527 PolarHBondContact O-N 3.01Å; N524-R527 PolarHBondContact O-N 3.06Å; N524-R527 PolarHBondContact OD1-NE 2.98Å; N524-R527 PolarHBondContact OD1-NH2 3.34Å; R527-S529 VanDerWaalsContact C-N 3.29Å; R527-S529 PolarHBondContact O-N 2.82Å; R527-F530 PolarHBondContact O-N 3.22Å; R527-Q531 WeakPolarHBondContact O-CB 3.26Å; R527-Q531 VanDerWaalsContact O-CG 3.31Å; R527-Q531 WeakPolarHBondContact O-CG 3.27Å; R527-Q531 PolarHBondContact O-N 3.01Å
528V95.6Very high95Very high48 Ų4844.1 Ų44.129%0.29124%0.238SC..Hα-helixtrans-62.4-39.4179.4170.20000110.8N524 A525 T526 S532N524-V528 WeakPolarHBondContact O-CG2 3.39Å; N524-V528 PolarHBondContact O-N 2.94Å; A525-V528 PolarHBondContact O-N 3.37Å; T526-V528 PolarHBondContact O-N 3.46Å; V528-S532 WeakPolarHBondContact O-CB 3.35Å; V528-S532 PolarHBondContact O-N 3.04Å; V528-S532 PolarHBondContact O-OG 3.49Å
529S97.2Very high95.5Very high3 Ų342 Ų422%0.02123%0.234CC..Hα-helixtrans-67.5-43.9179.2-60.70000111.9T398 A525 T526 R527 S532 H533T398-S529 WeakPolarHBondContact OG1-CB 3.31Å; T398-S529 PolarHBondContact OG1-OG 3.25Å; A525-S529 WeakPolarHBondContact O-CB 3.26Å; A525-S529 PolarHBondContact O-N 2.95Å; A525-S529 PolarHBondContact O-OG 3.29Å; T526-S529 PolarHBondContact O-N 3.2Å; R527-S529 VanDerWaalsContact C-N 3.29Å; R527-S529 PolarHBondContact O-N 2.82Å; S529-S532 PolarHBondContact O-N 3.43Å; S529-H533 PolarHBondContact O-N 3.05Å
530F97.3Very high96Very high14 Ų1441.6 Ų41.66%0.06123%0.231CC..Hα-helixtrans-58.8-50.4173.6179.9-92.8000111.4F271 I277 E505 F509 T526 R527 S532 H533 V534F271-F530 HydrophobicContact CE2-CB 3.95Å; F271-F530 HydrophobicContact CE2-CD2 4.24Å; F271-F530 HydrophobicContact CZ-CB 4.41Å; F271-F530 AromaticContact CZ-CD2 3.91Å; F271-F530 HydrophobicContact CZ-CD2 3.91Å; I277-F530 HydrophobicContact CD1-CD2 4.01Å; I277-F530 HydrophobicContact CD1-CE2 3.9Å; E505-F530 VanDerWaalsContact C-CE1 3.45Å; E505-F530 HydrophobicContact CB-CE1 4.05Å; E505-F530 HydrophobicContact CB-CZ 4.4Å; E505-F530 HydrophobicContact CG-CE1 4.01Å; E505-F530 HydrophobicContact CG-CZ 3.85Å; E505-F530 WeakPolarHBondContact O-CD1 3Å; E505-F530 WeakPolarHBondContact O-CE1 3.47Å; F509-F530 HydrophobicContact CD2-CD2 4.05Å; F509-F530 HydrophobicContact CD2-CE2 4.31Å; F509-F530 HydrophobicContact CE2-CD2 4.19Å; F509-F530 HydrophobicContact CE2-CE2 4.08Å; T526-F530 WeakPolarHBondContact O-CB 3.35Å; T526-F530 PolarHBondContact O-N 3.48Å; R527-F530 PolarHBondContact O-N 3.22Å; F530-S532 VanDerWaalsContact C-N 3.29Å; F530-S532 PolarHBondContact O-N 3.38Å; F530-H533 PolarHBondContact O-N 2.85Å; F530-H533 VanDerWaalsContact O-N 3.16Å; F530-V534 HydrophobicContact CD1-CG2 4.1Å; F530-V534 HydrophobicContact CE1-CG2 3.61Å; F530-V534 HydrophobicContact CE2-CG2 4.37Å; F530-V534 HydrophobicContact CZ-CG2 3.76Å; F530-V534 WeakPolarHBondContact O-CG2 3.43Å; F530-V534 PolarHBondContact O-N 3.41Å
531Q96.9Very high96.2Very high96 Ų9645.8 Ų45.845%0.44925%0.246SC..Hα-helixtrans-59.8-39.5177.5-72.8173.9-16.600112.3R527 V534 S535R527-Q531 WeakPolarHBondContact O-CB 3.26Å; R527-Q531 VanDerWaalsContact O-CG 3.31Å; R527-Q531 WeakPolarHBondContact O-CG 3.27Å; R527-Q531 PolarHBondContact O-N 3.01Å; Q531-V534 PolarHBondContact O-N 3.22Å; Q531-S535 WeakPolarHBondContact O-CB 2.86Å; Q531-S535 PolarHBondContact O-N 3.29Å
532S97.2Very high96.4Very high59 Ų5945.9 Ų45.941%0.41325%0.253SS..Hα-helixtrans-63.7-41.9177.1-56.10000111.3V528 S529 F530 S535 L536V528-S532 WeakPolarHBondContact O-CB 3.35Å; V528-S532 PolarHBondContact O-N 3.04Å; V528-S532 PolarHBondContact O-OG 3.49Å; S529-S532 PolarHBondContact O-N 3.43Å; F530-S532 VanDerWaalsContact C-N 3.29Å; F530-S532 PolarHBondContact O-N 3.38Å; S532-S535 PolarHBondContact O-N 3.38Å; S532-L536 WeakPolarHBondContact O-CB 3.37Å; S532-L536 PolarHBondContact O-N 2.99Å
533H97.9Very high96.7Very high12 Ų1248.4 Ų48.46%0.05627%0.269CS..Hα-helixtrans-66.8-43.3176.1177.874.2000112.1S267 V269 S529 F530 S535 L536 V537S267-H533 PolarHBondContact OG-CE1 2.8Å; S267-H533 VanDerWaalsContact OG-CE1 3.31Å; V269-H533 HydrophobicContact CB-CB 4.43Å; V269-H533 HydrophobicContact CG1-CB 3.9Å; V269-H533 WeakPolarHBondContact CG1-ND1 3.42Å; S529-H533 PolarHBondContact O-N 3.05Å; F530-H533 PolarHBondContact O-N 2.85Å; F530-H533 VanDerWaalsContact O-N 3.16Å; H533-S535 VanDerWaalsContact C-N 3.33Å; H533-S535 PolarHBondContact O-N 2.97Å; H533-L536 WeakPolarHBondContact O-CB 3.34Å; H533-L536 PolarHBondContact O-N 3.45Å; H533-V537 WeakPolarHBondContact O-CG2 3.35Å; H533-V537 PolarHBondContact O-N 3.06Å
534V97.9Very high96.9Very high60 Ų6051.5 Ų51.536%0.36429%0.285SS..Hα-helixtrans-60-43.7175.8172.70000111.2F530 Q531 V537 D538F530-V534 HydrophobicContact CD1-CG2 4.1Å; F530-V534 HydrophobicContact CE1-CG2 3.61Å; F530-V534 HydrophobicContact CE2-CG2 4.37Å; F530-V534 HydrophobicContact CZ-CG2 3.76Å; F530-V534 WeakPolarHBondContact O-CG2 3.43Å; F530-V534 PolarHBondContact O-N 3.41Å; Q531-V534 PolarHBondContact O-N 3.22Å; V534-V537 PolarHBondContact O-N 3.42Å; V534-D538 PolarHBondContact O-N 2.86Å
535S98.1Very high97Very high63 Ų6349.5 Ų49.544%0.44128%0.275SS..Hα-helixtrans-61.4-44.1174.9-168.90000111.8Q531 S532 H533 V537 D538 D539Q531-S535 WeakPolarHBondContact O-CB 2.86Å; Q531-S535 PolarHBondContact O-N 3.29Å; S532-S535 PolarHBondContact O-N 3.38Å; H533-S535 VanDerWaalsContact C-N 3.33Å; H533-S535 PolarHBondContact O-N 2.97Å; S535-V537 PolarHBondContact O-N 2.85Å; S535-D538 WeakPolarHBondContact O-CB 3.39Å; S535-D538 PolarHBondContact O-N 3.42Å; S535-D539 PolarHBondContact O-N 3.45Å
536L98.5Very high97Very high21 Ų2149.4 Ų49.411%0.1127%0.274CS..Hα-helixtrans-59.9-46177.4176.171.2000111.7A143 T400 L402 S532 H533 D538 D539 L540A143-L536 HydrophobicContact CB-CD1 3.68Å; T400-L536 HydrophobicContact CG2-CD2 3.57Å; L402-L536 HydrophobicContact CD2-CD2 4.24Å; S532-L536 WeakPolarHBondContact O-CB 3.37Å; S532-L536 PolarHBondContact O-N 2.99Å; H533-L536 WeakPolarHBondContact O-CB 3.34Å; H533-L536 PolarHBondContact O-N 3.45Å; L536-D538 VanDerWaalsContact C-N 3.3Å; L536-D538 PolarHBondContact O-N 2.87Å; L536-D539 PolarHBondContact O-N 2.89Å; L536-L540 HydrophobicContact CD1-CD1 4.11Å; L536-L540 HydrophobicContact CD1-CG 4.45Å; L536-L540 HydrophobicContact CG-CD1 4.03Å; L536-L540 WeakPolarHBondContact O-CB 3.46Å; L536-L540 VanDerWaalsContact O-CG 3.26Å; L536-L540 WeakPolarHBondContact O-CG 3.43Å; L536-L540 PolarHBondContact O-N 3.09Å
537V98.2Very high97Very high63 Ų6349.4 Ų49.438%0.38228%0.275SS..Hα-helixtrans-63.2-37.9177.2172.50000111.1S267 H533 V534 S535 L540 K541S267-V537 VanDerWaalsContact OG-CG2 3.28Å; S267-V537 WeakPolarHBondContact OG-CG2 3.48Å; H533-V537 WeakPolarHBondContact O-CG2 3.35Å; H533-V537 PolarHBondContact O-N 3.06Å; V534-V537 PolarHBondContact O-N 3.42Å; S535-V537 PolarHBondContact O-N 2.85Å; V537-L540 PolarHBondContact O-N 3.33Å; V537-K541 PolarHBondContact O-N 3.13Å
538D98.3Very high96.9Very high85 Ų8550.1 Ų50.146%0.45528%0.277SS..Hα-helixtrans-63.8-46.9175.1-166.162.5000112V534 S535 L536 L540 K541V534-D538 PolarHBondContact O-N 2.86Å; S535-D538 WeakPolarHBondContact O-CB 3.39Å; S535-D538 PolarHBondContact O-N 3.42Å; L536-D538 VanDerWaalsContact C-N 3.3Å; L536-D538 PolarHBondContact O-N 2.87Å; D538-L540 PolarHBondContact O-N 3.47Å; D538-K541 WeakPolarHBondContact O-CB 3.41Å; D538-K541 WeakPolarHBondContact O-CG 3.41Å; D538-K541 PolarHBondContact O-N 2.96Å; D538-K541 VanDerWaalsContact O-N 3.14Å; D538-K541 WeakPolarHBondContact OD1-CD 3.46Å; D538-K541 VanDerWaalsContact OD1-CE 3.28Å; D538-K541 WeakPolarHBondContact OD1-CE 3.33Å; D538-K541 IonicContact OD1-NZ 3.26Å; D538-K541 PolarHBondContact OD1-NZ 2.77Å
539D98.4Very high96.9Very high59 Ų5948.8 Ų48.832%0.31627%0.268SS..Hα-helixtrans-62.5-31.3178.2-73-28.8000112.4A139 Q140 A143 S535 L536 K541A139-D539 HydrophobicContact CB-CB 4.14Å; Q140-D539 WeakPolarHBondContact CG-O 3.45Å; A143-D539 HydrophobicContact CB-CB 3.85Å; S535-D539 PolarHBondContact O-N 3.45Å; L536-D539 PolarHBondContact O-N 2.89Å; D539-K541 VanDerWaalsContact C-N 3.35Å
540L98.1Very high96.7Very high9 Ų952.2 Ų52.25%0.04729%0.291CS..THydrogen-bonded Turntrans-83-4178.8-70.1175.2000114.2A143 S264 P265 L402 L536 V537 D538A143-L540 HydrophobicContact CB-CD2 3.55Å; A143-L540 HydrophobicContact CB-CG 3.78Å; S264-L540 WeakPolarHBondContact CB-O 3Å; S264-L540 PolarHBondContact OG-O 2.87Å; P265-L540 HydrophobicContact CG-CD1 4.2Å; P265-L540 HydrophobicContact CG-CD2 3.85Å; L402-L540 HydrophobicContact CD2-CD1 3.69Å; L536-L540 HydrophobicContact CD1-CD1 4.11Å; L536-L540 HydrophobicContact CD1-CG 4.45Å; L536-L540 HydrophobicContact CG-CD1 4.03Å; L536-L540 WeakPolarHBondContact O-CB 3.46Å; L536-L540 VanDerWaalsContact O-CG 3.26Å; L536-L540 WeakPolarHBondContact O-CG 3.43Å; L536-L540 PolarHBondContact O-N 3.09Å; V537-L540 PolarHBondContact O-N 3.33Å; D538-L540 PolarHBondContact O-N 3.47Å
541K96.8Very high96.6Very high117 Ų11754.6 Ų54.651%0.50931%0.308SS..  trans-53.4132.9-178.4-79.8174.3179.5168.10111.7Q140 V537 D538 D539 V543Q140-K541 PolarHBondContact NE2-O 2.87Å; V537-K541 PolarHBondContact O-N 3.13Å; D538-K541 WeakPolarHBondContact O-CB 3.41Å; D538-K541 WeakPolarHBondContact O-CG 3.41Å; D538-K541 PolarHBondContact O-N 2.96Å; D538-K541 VanDerWaalsContact O-N 3.14Å; D538-K541 WeakPolarHBondContact OD1-CD 3.46Å; D538-K541 VanDerWaalsContact OD1-CE 3.28Å; D538-K541 WeakPolarHBondContact OD1-CE 3.33Å; D538-K541 IonicContact OD1-NZ 3.26Å; D538-K541 PolarHBondContact OD1-NZ 2.77Å; D539-K541 VanDerWaalsContact C-N 3.35Å; K541-V543 PolarHBondContact O-N 3.39Å
542P95.3Very high96.5Very high117 Ų11750.7 Ų50.776%0.7629%0.29SS*.  trans-59139.8175.5-24.934.1000111.6
543V96.3Very high96.4Very high59 Ų5951.5 Ų51.536%0.35830%0.301SS..  trans-120.8156.5175.3-58.20000110.3C136 T137 K541 L563C136-V543 HydrophobicContact CB-CG2 3.25Å; T137-V543 HydrophobicContact CG2-CG1 4.4Å; T137-V543 HydrophobicContact CG2-CG2 4.36Å; K541-V543 PolarHBondContact O-N 3.39Å; V543-L563 HydrophobicContact CG2-CD1 4.48Å; V543-L563 HydrophobicContact CG2-CD2 3.96Å
544I96.4Very high96.3Very high64 Ų6454.5 Ų54.533%0.32832%0.317SS..  trans-100.4120.9-178.9-59.1-179.2000109.2L563 Q564 R588I544-L563 CarbonylContact O-C 3.49Å; I544-L563 VanDerWaalsContact O-CA 3.3Å; I544-L563 WeakPolarHBondContact O-CA 3.37Å; I544-Q564 HydrophobicContact CB-CB 4.2Å; I544-Q564 PolarHBondContact O-N 3.42Å; I544-R588 VanDerWaalsContact CD1-O 3.26Å; I544-R588 WeakPolarHBondContact CD1-O 3.41Å
545S96.1Very high96.2Very high15 Ų1552.3 Ų52.311%0.10531%0.307CS..BIsolated β-bridgetrans-110.9134.9172.7-179.20000110.5G547 Y562S545-G547 PolarHBondContact OG-N 2.63Å; S545-Y562 WeakPolarHBondContact CA-O 3.33Å
546C96Very high96.1Very high6 Ų655.5 Ų55.54%0.04131%0.313CS..  trans-90.4-5.7172.4-62.60000112.9Y562 C586 Q587 G590 K591 W592C546-Y562 PolarHBondContact N-O 2.73Å; C546-C586 HydrophobicContact CB-CB 3.72Å; C546-C586 WeakPolarHBondContact CB-SG 3.31Å; C546-C586 PolarHBondContact N-SG 3.08Å; C546-C586 VanDerWaalsContact N-SG 3.4Å; C546-C586 WeakPolarHBondContact SG-CA 3.22Å; C546-C586 WeakPolarHBondContact SG-CB 3.47Å; C546-C586 CovalentContact SG-SG 2.02Å; C546-C586 PolarHBondContact SG-SG 2.89Å; C546-Q587 PolarHBondContact SG-N 2.97Å; C546-G590 WeakPolarHBondContact CA-O 3.3Å; C546-K591 VanDerWaalsContact SG-C 3.52Å; C546-K591 PolarHBondContact SG-N 2.85Å; C546-K591 PolarHBondContact SG-O 3.27Å; C546-K591 VanDerWaalsContact SG-O 3.36Å; C546-W592 HydrophobicContact CB-CD2 3.97Å; C546-W592 VanDerWaalsContact CB-CE2 3.44Å; C546-W592 HydrophobicContact CB-CG 4.05Å; C546-W592 HydrophobicContact CB-CZ2 3.83Å; C546-W592 VanDerWaalsContact CB-NE1 3.27Å; C546-W592 PolarHBondContact O-NE1 3.35Å
547G93.9Very high96Very high1 Ų156.4 Ų56.41%0.0132%0.316CS..  trans76.6168.8-177.600000113.6S545 Y562 W592S545-G547 PolarHBondContact OG-N 2.63Å; G547-Y562 VanDerWaalsContact O-CD1 3.27Å; G547-Y562 WeakPolarHBondContact O-CD1 3.44Å; G547-W592 PolarHBondContact O-NE1 3.2Å
548W94.6Very high95.9Very high81 Ų8160 Ų6031%0.30733%0.328SS..  trans-68.4147.4-178.9178.294.9000112.4L197 A199 D200 P550 Y562L197-W548 HydrophobicContact CD1-CB 3.91Å; L197-W548 HydrophobicContact CD1-CG 4.28Å; A199-W548 HydrophobicContact CB-CD2 4.07Å; A199-W548 HydrophobicContact CB-CG 4.45Å; A199-W548 HydrophobicContact CB-CH2 4.22Å; A199-W548 HydrophobicContact CB-CZ2 3.52Å; D200-W548 PolarHBondContact OD1-NE1 3.35Å; W548-P550 HydrophobicContact CH2-CB 3.47Å; W548-P550 VanDerWaalsContact CH2-CB 3.47Å; W548-P550 HydrophobicContact CZ2-CB 4.3Å; W548-P550 HydrophobicContact CZ3-CB 3.58Å; W548-P550 HydrophobicContact CZ3-CG 4.22Å; W548-Y562 HydrophobicContact CB-CE1 4.33Å; W548-Y562 HydrophobicContact CB-CE2 4.47Å; W548-Y562 AromaticContact CD1-CE2 3.97Å; W548-Y562 AromaticContact CD1-CZ 3.46Å; W548-Y562 VanDerWaalsContact CD1-CZ 3.46Å; W548-Y562 HydrophobicContact CG-CE1 4.41Å
549L94.5Very high95.7Very high20 Ų2057.1 Ų57.111%0.10532%0.319CS..  trans-115.3137.3171.1-68.5178.6000110.2K557 F570 R584 W592L549-K557 WeakPolarHBondContact O-CD 3.42Å; L549-K557 PolarHBondContact O-NZ 2.79Å; L549-F570 HydrophobicContact CB-CZ 4Å; L549-F570 HydrophobicContact CD1-CE2 4.19Å; L549-F570 HydrophobicContact CD1-CZ 3.77Å; L549-R584 HydrophobicContact CD1-CB 4.39Å; L549-W592 HydrophobicContact CD1-CB 4.3Å; L549-W592 HydrophobicContact CD1-CD2 3.6Å; L549-W592 HydrophobicContact CD1-CE3 4.1Å; L549-W592 HydrophobicContact CD1-CG 3.65Å; L549-W592 HydrophobicContact CD2-CG 4.11Å; L549-W592 HydrophobicContact CG-CD2 4.15Å; L549-W592 HydrophobicContact CG-CG 4.05Å
550P93.8Very high95.5Very high76 Ų7657.8 Ų57.849%0.49433%0.325SS..PPolyproline II helixtrans-72148.6175.328.9-33.5000112.5W548 F570W548-P550 HydrophobicContact CH2-CB 3.47Å; W548-P550 VanDerWaalsContact CH2-CB 3.47Å; W548-P550 HydrophobicContact CZ2-CB 4.3Å; W548-P550 HydrophobicContact CZ3-CB 3.58Å; W548-P550 HydrophobicContact CZ3-CG 4.22Å; P550-F570 WeakPolarHBondContact O-CE1 3.03Å
551P94.6Very high95.3Very high64 Ų6463.6 Ų63.642%0.41635%0.347SS..PPolyproline II helixtrans-64143163.629.3-33.2000110.3K557P551-K557 HydrophobicContact CB-CB 3.94Å
552P95.7Very high95.2Very high13 Ų1358.8 Ų58.88%0.08433%0.325CS..PPolyproline II helixtrans-64.6147172.927-33.8000110.4N554 G555 F570P552-N554 PolarHBondContact O-N 2.89Å; P552-G555 CarbonylContact O-C 3.57Å; P552-G555 PolarHBondContact O-N 3.3Å; P552-G555 VanDerWaalsContact O-N 3.08Å; P552-F570 HydrophobicContact CG-CD1 4.37Å
553A94.9Very high95.3Very high77 Ų7755.6 Ų55.664%0.63630%0.302SS*.THydrogen-bonded Turntrans-60.5133.3172.200000110.3G555 C599A553-G555 VanDerWaalsContact C-N 3.3Å; A553-C599 WeakPolarHBondContact O-CB 3.38Å
554N95.5Very high95.3Very high75 Ų7557.1 Ų57.140%0.40131%0.305SS..THydrogen-bonded Turntrans58.340.6-171-44.1-72.8000112.9P552 D573 Y576 C599P552-N554 PolarHBondContact O-N 2.89Å; N554-D573 VanDerWaalsContact CA-OD2 3.31Å; N554-D573 WeakPolarHBondContact CA-OD2 3.19Å; N554-D573 PolarHBondContact O-N 2.97Å; N554-Y576 HydrophobicContact CB-CD1 3.77Å; N554-Y576 HydrophobicContact CB-CD2 3.81Å; N554-Y576 HydrophobicContact CB-CE1 3.63Å; N554-Y576 HydrophobicContact CB-CE2 3.67Å; N554-Y576 HydrophobicContact CB-CG 3.87Å; N554-Y576 VanDerWaalsContact CG-CZ 3.42Å; N554-Y576 PolarHBondContact OD1-OH 2.9Å; N554-C599 WeakPolarHBondContact O-CB 3.32Å
555G95.6Very high95.4Very high14 Ų1456.4 Ų56.414%0.14431%0.314CS..EExtended strand (participates in β ladder)trans-161.7-177.617500000112.4P552 A553 S571 D573P552-G555 CarbonylContact O-C 3.57Å; P552-G555 PolarHBondContact O-N 3.3Å; P552-G555 VanDerWaalsContact O-N 3.08Å; A553-G555 VanDerWaalsContact C-N 3.3Å; G555-S571 CarbonylContact C-O 3.53Å; G555-S571 WeakPolarHBondContact CA-O 3.02Å; G555-D573 PolarHBondContact N-OD2 2.95Å
556K95.9Very high95.4Very high130 Ų13056.6 Ų56.657%0.56532%0.316SS*.EExtended strand (participates in β ladder)trans-127.7152.7-171.5-59.7177.7-174.7170.70110.2F570 S571 D573K556-F570 WeakPolarHBondContact O-CA 3.27Å; K556-S571 PolarHBondContact N-O 3.15Å; K556-S571 PolarHBondContact O-N 3.25Å; K556-D573 VanDerWaalsContact CE-OD1 3.24Å; K556-D573 WeakPolarHBondContact CE-OD1 3.35Å
557K96.3Very high95.5Very high39 Ų3961.9 Ų61.917%0.1734%0.338CS..EExtended strand (participates in β ladder)trans-116.5134.3171.6-176.9-171.471.6171.70109.1D200 L549 P551 Y562 V568 K569 F570D200-K557 WeakPolarHBondContact OD1-CE 3.37Å; D200-K557 IonicContact OD1-NZ 3.4Å; D200-K557 PolarHBondContact OD1-NZ 2.81Å; D200-K557 IonicContact OD2-NZ 2.79Å; L549-K557 WeakPolarHBondContact O-CD 3.42Å; L549-K557 PolarHBondContact O-NZ 2.79Å; P551-K557 HydrophobicContact CB-CB 3.94Å; K557-Y562 PolarHBondContact NZ-OH 3.48Å; K557-V568 HydrophobicContact CD-CG1 3.67Å; K557-V568 HydrophobicContact CG-CG1 3.35Å; K557-K569 CarbonylContact C-O 3.55Å; K557-K569 WeakPolarHBondContact CA-O 3.37Å; K557-F570 HydrophobicContact CB-CD1 4.11Å; K557-F570 HydrophobicContact CB-CE1 4.03Å; K557-F570 HydrophobicContact CD-CE1 4.02Å; K557-F570 HydrophobicContact CG-CD1 4.09Å; K557-F570 HydrophobicContact CG-CE1 3.65Å; K557-F570 HydrophobicContact CG-CZ 4.34Å
558Q96.6Very high95.7Very high138 Ų13861.8 Ų61.865%0.64534%0.338SS*.EExtended strand (participates in β ladder)trans-116.1127171.6-175.7179.449.700109.8V568 K569Q558-V568 WeakPolarHBondContact O-CA 3.18Å; Q558-K569 HydrophobicContact CB-CB 4.31Å; Q558-K569 PolarHBondContact N-O 2.54Å; Q558-K569 PolarHBondContact O-N 3.41Å
559G93.9Very high95.9Very high26 Ų2662.4 Ų62.427%0.26834%0.343SS..  trans116.9132.7-178.200000111.7
560T93.9Very high96Very high72 Ų7261.9 Ų61.944%0.44234%0.339SS..  trans-12511.9-175.755.30000112.3D200 Y562D200-T560 HydrophobicContact CB-CG2 3.86Å; T560-Y562 WeakPolarHBondContact O-CE2 3.24Å
561R94.6Very high96.2Very high131 Ų13161.1 Ų61.149%0.49434%0.336SS..  trans-110.2140.2178.2-64.4-175-176.9162.95.1110.1T192 A194 A566T192-R561 PolarHBondContact OG1-NE 2.71Å; T192-R561 PolarHBondContact OG1-NH2 2.8Å; A194-R561 HydrophobicContact CB-CG 4.25Å; R561-A566 HydrophobicContact CB-CB 3.94Å; R561-A566 VanDerWaalsContact O-CB 3.25Å; R561-A566 WeakPolarHBondContact O-CB 3.38Å
562Y95.6Very high96.3Very high16 Ų1659.4 Ų59.46%0.06333%0.325CS..  trans-128.84.5-171.5-52.8-69.4000113.9L197 D200 S545 C546 G547 W548 K557 T560 V568 C586 W592L197-Y562 HydrophobicContact CD1-CD2 3.77Å; L197-Y562 HydrophobicContact CD1-CE2 3.5Å; L197-Y562 VanDerWaalsContact CD1-CE2 3.5Å; L197-Y562 HydrophobicContact CG-CE2 4.34Å; D200-Y562 PolarHBondContact OD1-OH 2.8Å; D200-Y562 VanDerWaalsContact OD1-OH 3.11Å; D200-Y562 WeakPolarHBondContact OD2-CE2 3.39Å; D200-Y562 VanDerWaalsContact OD2-CZ 3.29Å; D200-Y562 PolarHBondContact OD2-OH 3.08Å; S545-Y562 WeakPolarHBondContact CA-O 3.33Å; C546-Y562 PolarHBondContact N-O 2.73Å; G547-Y562 VanDerWaalsContact O-CD1 3.27Å; G547-Y562 WeakPolarHBondContact O-CD1 3.44Å; W548-Y562 HydrophobicContact CB-CE1 4.33Å; W548-Y562 HydrophobicContact CB-CE2 4.47Å; W548-Y562 AromaticContact CD1-CE2 3.97Å; W548-Y562 AromaticContact CD1-CZ 3.46Å; W548-Y562 VanDerWaalsContact CD1-CZ 3.46Å; W548-Y562 HydrophobicContact CG-CE1 4.41Å; K557-Y562 PolarHBondContact NZ-OH 3.48Å; T560-Y562 WeakPolarHBondContact O-CE2 3.24Å; Y562-V568 HydrophobicContact CE1-CG2 4.33Å; Y562-C586 PolarHBondContact O-SG 3.43Å; Y562-W592 HydrophobicContact CD1-CH2 4.28Å; Y562-W592 AromaticContact CD1-CZ2 3.7Å; Y562-W592 HydrophobicContact CD1-CZ2 3.7Å; Y562-W592 HydrophobicContact CG-CZ2 4.47Å
563L96.6Very high96.4Very high50 Ų5061.6 Ų61.626%0.26234%0.336SS..BIsolated β-bridgetrans-78.6161.8175.9-58.2-175.6000111.9C136 T137 V543 I544 G565 A566 C586C136-L563 HydrophobicContact CB-CD2 4.07Å; T137-L563 HydrophobicContact CG2-CD1 3.93Å; V543-L563 HydrophobicContact CG2-CD1 4.48Å; V543-L563 HydrophobicContact CG2-CD2 3.96Å; I544-L563 CarbonylContact O-C 3.49Å; I544-L563 VanDerWaalsContact O-CA 3.3Å; I544-L563 WeakPolarHBondContact O-CA 3.37Å; L563-G565 PolarHBondContact O-N 2.83Å; L563-A566 WeakPolarHBondContact O-CB 3.2Å; L563-A566 PolarHBondContact O-N 3.36Å; L563-C586 VanDerWaalsContact C-SG 3.56Å; L563-C586 WeakPolarHBondContact O-CB 3.31Å
564Q97.3Very high96.2Very high91 Ų9165 Ų6543%0.42534%0.344SS..THydrogen-bonded Turntrans-45.7130.3178.5-175.9-169.4-38.500112.4I544 A566 C586 R588I544-Q564 HydrophobicContact CB-CB 4.2Å; I544-Q564 PolarHBondContact O-N 3.42Å; Q564-A566 VanDerWaalsContact C-N 3.27Å; Q564-A566 PolarHBondContact O-N 3.49Å; Q564-C586 VanDerWaalsContact CA-SG 3.58Å; Q564-R588 HydrophobicContact CG-CG 4.34Å
565G97.1Very high96Very high50 Ų5068.3 Ų68.352%0.51536%0.361SS..THydrogen-bonded Turntrans84.9-10.5-17800000114.5L563 C586L563-G565 PolarHBondContact O-N 2.83Å; G565-C586 PolarHBondContact N-O 3.3Å
566A97.1Very high96Very high18 Ų1871.5 Ų71.515%0.14937%0.37CS..  trans-62.5148.1171.800000111.2R561 L563 Q564 T585 C586 W592R561-A566 HydrophobicContact CB-CB 3.94Å; R561-A566 VanDerWaalsContact O-CB 3.25Å; R561-A566 WeakPolarHBondContact O-CB 3.38Å; L563-A566 WeakPolarHBondContact O-CB 3.2Å; L563-A566 PolarHBondContact O-N 3.36Å; Q564-A566 VanDerWaalsContact C-N 3.27Å; Q564-A566 PolarHBondContact O-N 3.49Å; A566-T585 CarbonylContact O-C 3.55Å; A566-T585 VanDerWaalsContact O-CA 3.29Å; A566-T585 WeakPolarHBondContact O-CA 3.35Å; A566-C586 PolarHBondContact O-N 3.17Å; A566-W592 HydrophobicContact CB-CH2 4.3Å; A566-W592 WeakPolarHBondContact O-CZ3 3.43Å
567K97.8Very high95.9Very high117 Ų11772.2 Ų72.251%0.50937%0.373SS..EExtended strand (participates in β ladder)trans-122.6133.5-180-68.7179.3164.7-143.40109.8E583 R584 T585K567-E583 HydrophobicContact CB-CG 4.33Å; K567-E583 WeakPolarHBondContact CD-OE1 3.48Å; K567-E583 WeakPolarHBondContact CE-OE1 3.35Å; K567-E583 IonicContact NZ-OE1 3.45Å; K567-E583 PolarHBondContact NZ-OE1 3.4Å; K567-R584 WeakPolarHBondContact CA-O 3.46Å; K567-T585 HydrophobicContact CG-CG2 4.28Å
568V97.8Very high95.9Very high0 Ų072.7 Ų72.70%038%0.377CS..EExtended strand (participates in β ladder)trans-120.3129.1175.4177.20000107.9K557 Q558 Y562 F570 E583 R584 W592K557-V568 HydrophobicContact CD-CG1 3.67Å; K557-V568 HydrophobicContact CG-CG1 3.35Å; Q558-V568 WeakPolarHBondContact O-CA 3.18Å; Y562-V568 HydrophobicContact CE1-CG2 4.33Å; V568-F570 HydrophobicContact CB-CE2 4.45Å; V568-F570 HydrophobicContact CB-CZ 4.43Å; V568-F570 HydrophobicContact CG1-CE1 3.98Å; V568-F570 HydrophobicContact CG1-CE2 3.85Å; V568-F570 HydrophobicContact CG1-CZ 3.51Å; V568-E583 CarbonylContact O-C 3.47Å; V568-E583 WeakPolarHBondContact O-CA 3.37Å; V568-R584 PolarHBondContact N-O 2.91Å; V568-R584 PolarHBondContact O-N 3.08Å; V568-W592 HydrophobicContact CB-CZ3 4.29Å; V568-W592 HydrophobicContact CG2-CH2 3.62Å; V568-W592 HydrophobicContact CG2-CZ2 4.33Å; V568-W592 HydrophobicContact CG2-CZ3 3.83Å
569K98.1Very high95.8Very high94 Ų9469.3 Ų69.341%0.40937%0.369SS..EExtended strand (participates in β ladder)trans-107.9145.1178.1-67.7-176.8176.3-175.10111.1K557 Q558 E582 E583K557-K569 CarbonylContact C-O 3.55Å; K557-K569 WeakPolarHBondContact CA-O 3.37Å; Q558-K569 HydrophobicContact CB-CB 4.31Å; Q558-K569 PolarHBondContact N-O 2.54Å; Q558-K569 PolarHBondContact O-N 3.41Å; K569-E582 CarbonylContact C-O 3.6Å; K569-E582 VanDerWaalsContact CA-O 3.25Å; K569-E582 WeakPolarHBondContact CA-O 3.46Å; K569-E583 WeakPolarHBondContact CE-OE2 3.45Å; K569-E583 HydrophobicContact CG-CB 4.21Å; K569-E583 HydrophobicContact CG-CG 4.05Å; K569-E583 IonicContact NZ-OE2 3.5Å
570F98.3Very high95.9Very high8 Ų869.7 Ų69.74%0.03537%0.373CS..EExtended strand (participates in β ladder)trans-121.9138.2179.3-59.4-77.7000110.2L549 P550 P552 K556 K557 V568 L578 E582 R584 A597L549-F570 HydrophobicContact CB-CZ 4Å; L549-F570 HydrophobicContact CD1-CE2 4.19Å; L549-F570 HydrophobicContact CD1-CZ 3.77Å; P550-F570 WeakPolarHBondContact O-CE1 3.03Å; P552-F570 HydrophobicContact CG-CD1 4.37Å; K556-F570 WeakPolarHBondContact O-CA 3.27Å; K557-F570 HydrophobicContact CB-CD1 4.11Å; K557-F570 HydrophobicContact CB-CE1 4.03Å; K557-F570 HydrophobicContact CD-CE1 4.02Å; K557-F570 HydrophobicContact CG-CD1 4.09Å; K557-F570 HydrophobicContact CG-CE1 3.65Å; K557-F570 HydrophobicContact CG-CZ 4.34Å; V568-F570 HydrophobicContact CB-CE2 4.45Å; V568-F570 HydrophobicContact CB-CZ 4.43Å; V568-F570 HydrophobicContact CG1-CE1 3.98Å; V568-F570 HydrophobicContact CG1-CE2 3.85Å; V568-F570 HydrophobicContact CG1-CZ 3.51Å; F570-L578 HydrophobicContact CB-CD1 4.32Å; F570-E582 PolarHBondContact N-O 3.44Å; F570-R584 HydrophobicContact CE2-CB 4.43Å; F570-R584 HydrophobicContact CE2-CG 3.97Å; F570-A597 HydrophobicContact CB-CB 3.68Å; F570-A597 HydrophobicContact CD1-CB 4.13Å; F570-A597 HydrophobicContact CD2-CB 3.81Å; F570-A597 HydrophobicContact CE2-CB 4.5Å; F570-A597 HydrophobicContact CG-CB 3.59Å
571S97.4Very high96.1Very high61 Ų6167.7 Ų67.743%0.42736%0.362SS..EExtended strand (participates in β ladder)trans-133.7158.5171.759.90000109.6G555 K556G555-S571 CarbonylContact C-O 3.53Å; G555-S571 WeakPolarHBondContact CA-O 3.02Å; K556-S571 PolarHBondContact N-O 3.15Å; K556-S571 PolarHBondContact O-N 3.25Å
572C97.2Very high96.2Very high27 Ų2767.8 Ų67.818%0.18237%0.367CS..EExtended strand (participates in β ladder)trans-99.9154.5172.8-60.50000110.5L578 C599C572-L578 WeakPolarHBondContact SG-CA 2.96Å; C572-L578 PolarHBondContact SG-N 2.86Å; C572-C599 WeakPolarHBondContact CA-SG 3.24Å; C572-C599 HydrophobicContact CB-CB 3.71Å; C572-C599 WeakPolarHBondContact CB-SG 3.42Å; C572-C599 WeakPolarHBondContact SG-CA 3.49Å; C572-C599 WeakPolarHBondContact SG-CB 3.19Å; C572-C599 CovalentContact SG-SG 2.03Å; C572-C599 PolarHBondContact SG-SG 3.07Å
573D96.1Very high96.4Very high59 Ų5970.2 Ų70.232%0.31638%0.379SS..PPolyproline II helixtrans-66165.9169.3-64.4-37000110.4N554 G555 K556 Y576N554-D573 VanDerWaalsContact CA-OD2 3.31Å; N554-D573 WeakPolarHBondContact CA-OD2 3.19Å; N554-D573 PolarHBondContact O-N 2.97Å; G555-D573 PolarHBondContact N-OD2 2.95Å; K556-D573 VanDerWaalsContact CE-OD1 3.24Å; K556-D573 WeakPolarHBondContact CE-OD1 3.35Å; D573-Y576 HydrophobicContact CB-CD2 4.41Å; D573-Y576 WeakPolarHBondContact O-CB 3.36Å; D573-Y576 PolarHBondContact O-N 3.29Å; D573-Y576 VanDerWaalsContact O-N 3.12Å
574D92.3Very high96.4Very high150 Ų15068.8 Ų68.880%0.80237%0.371SS*.THydrogen-bonded Turntrans-54.4142.8178.9-62.8-28.4000110.6Y576D574-Y576 WeakPolarHBondContact O-CD2 3.4Å; D574-Y576 PolarHBondContact O-N 3.22Å
575D91.1Very high96.5Very high144 Ų14466.4 Ų66.477%0.7736%0.362SS*.THydrogen-bonded Turntrans71.2-2.9-173.9-55.1-43.9000117.2P602D575-P602 WeakPolarHBondContact O-CD 3.21Å
576Y94.3Very high96.5Very high81 Ų8164.1 Ų64.132%0.31834%0.338SS..  trans-103.8148.4173.2-67.9-96.8000112N554 D573 D574 C599 V601N554-Y576 HydrophobicContact CB-CD1 3.77Å; N554-Y576 HydrophobicContact CB-CD2 3.81Å; N554-Y576 HydrophobicContact CB-CE1 3.63Å; N554-Y576 HydrophobicContact CB-CE2 3.67Å; N554-Y576 HydrophobicContact CB-CG 3.87Å; N554-Y576 VanDerWaalsContact CG-CZ 3.42Å; N554-Y576 PolarHBondContact OD1-OH 2.9Å; D573-Y576 HydrophobicContact CB-CD2 4.41Å; D573-Y576 WeakPolarHBondContact O-CB 3.36Å; D573-Y576 PolarHBondContact O-N 3.29Å; D573-Y576 VanDerWaalsContact O-N 3.12Å; D574-Y576 WeakPolarHBondContact O-CD2 3.4Å; D574-Y576 PolarHBondContact O-N 3.22Å; Y576-C599 HydrophobicContact CD1-CB 4.39Å; Y576-C599 HydrophobicContact CG-CB 4.5Å; Y576-V601 HydrophobicContact CD1-CG2 4.15Å; Y576-V601 HydrophobicContact CE1-CG2 3.75Å
577K94.3Very high96.6Very high144 Ų14467.4 Ų67.463%0.62635%0.351SS*.EExtended strand (participates in β ladder)trans-113.7133.8175.4-170.6173.4-179.2-179.40110.8S600 P602K577-S600 PolarHBondContact N-O 2.69Å; K577-S600 PolarHBondContact O-N 3.46Å; K577-S600 VanDerWaalsContact O-N 3.11Å; K577-P602 HydrophobicContact CB-CG 4.3Å
578L95.8Very high96.6Very high50 Ų5071.6 Ų71.626%0.26236%0.363SS..EExtended strand (participates in β ladder)trans-70.4133.9177-170.872.6000111.1F570 C572 E582 A597 S598F570-L578 HydrophobicContact CB-CD1 4.32Å; C572-L578 WeakPolarHBondContact SG-CA 2.96Å; C572-L578 PolarHBondContact SG-N 2.86Å; L578-E582 HydrophobicContact CD2-CB 3.74Å; L578-E582 HydrophobicContact CD2-CG 4.03Å; L578-A597 HydrophobicContact CD1-CB 3.96Å; L578-S598 CarbonylContact C-O 3.51Å; L578-S598 WeakPolarHBondContact CA-O 3.34Å
579S96.1Very high96.5Very high67 Ų6776.4 Ų76.447%0.46939%0.389SS..EExtended strand (participates in β ladder)trans-123.1146.1166-1740000108.9A597 S598S579-A597 CarbonylContact O-C 3.57Å; S579-A597 WeakPolarHBondContact O-CA 3.47Å; S579-S598 PolarHBondContact N-O 2.86Å; S579-S598 PolarHBondContact O-N 3.3Å
580G96.1Very high96.4Very high34 Ų3473.1 Ų73.135%0.35138%0.382SS..SBendtrans90.4-157.6-170.200000112.7
581S97.6Very high96.3Very high30 Ų3079.4 Ų79.421%0.2141%0.409CS..  trans-89.2125.7-175.6-61.80000112.7E583 G594 E595S581-E583 VanDerWaalsContact C-N 3.34Å; S581-G594 WeakPolarHBondContact OG-CA 3.41Å; S581-E595 WeakPolarHBondContact CB-O 3.22Å; S581-E595 PolarHBondContact N-O 2.93Å; S581-E595 PolarHBondContact OG-N 2.89Å
582E97.4Very high96.3Very high132 Ų13277.6 Ų77.662%0.61739%0.393SS*.SBendtrans-66.1-34.6173.7-171.8-173.4163.900112.6K569 F570 L578K569-E582 CarbonylContact C-O 3.6Å; K569-E582 VanDerWaalsContact CA-O 3.25Å; K569-E582 WeakPolarHBondContact CA-O 3.46Å; F570-E582 PolarHBondContact N-O 3.44Å; L578-E582 HydrophobicContact CD2-CB 3.74Å; L578-E582 HydrophobicContact CD2-CG 4.03Å
583E98.3Very high96.4Very high68 Ų6877.6 Ų77.632%0.31839%0.393SS..EExtended strand (participates in β ladder)trans-129.5134.9176.4-175.1177.895.400109.9K567 V568 K569 S581K567-E583 HydrophobicContact CB-CG 4.33Å; K567-E583 WeakPolarHBondContact CD-OE1 3.48Å; K567-E583 WeakPolarHBondContact CE-OE1 3.35Å; K567-E583 IonicContact NZ-OE1 3.45Å; K567-E583 PolarHBondContact NZ-OE1 3.4Å; V568-E583 CarbonylContact O-C 3.47Å; V568-E583 WeakPolarHBondContact O-CA 3.37Å; K569-E583 WeakPolarHBondContact CE-OE2 3.45Å; K569-E583 HydrophobicContact CG-CB 4.21Å; K569-E583 HydrophobicContact CG-CG 4.05Å; K569-E583 IonicContact NZ-OE2 3.5Å; S581-E583 VanDerWaalsContact C-N 3.34Å
584R98.3Very high96.4Very high20 Ų2077.2 Ų77.28%0.07540%0.403CS..EExtended strand (participates in β ladder)trans-121.6138173.1-58.5-176.474.2177.815109.6L549 K567 V568 F570 W592 S593 G594 D596L549-R584 HydrophobicContact CD1-CB 4.39Å; K567-R584 WeakPolarHBondContact CA-O 3.46Å; V568-R584 PolarHBondContact N-O 2.91Å; V568-R584 PolarHBondContact O-N 3.08Å; F570-R584 HydrophobicContact CE2-CB 4.43Å; F570-R584 HydrophobicContact CE2-CG 3.97Å; R584-W592 HydrophobicContact CB-CB 4.44Å; R584-W592 HydrophobicContact CB-CE3 3.89Å; R584-W592 WeakPolarHBondContact O-CZ3 3.02Å; R584-S593 WeakPolarHBondContact CG-O 3.45Å; R584-S593 PolarHBondContact NE-O 3.45Å; R584-G594 PolarHBondContact NH2-O 3.45Å; R584-D596 IonicContact CZ-OD1 2.77Å; R584-D596 IonicContact NH1-OD1 3.26Å; R584-D596 PolarHBondContact NH1-OD1 3.18Å; R584-D596 IonicContact NH2-OD1 2.71Å; R584-D596 PolarHBondContact NH2-OD1 2.96Å
585T98.4Very high96.6Very high40 Ų4076.7 Ų76.725%0.24540%0.396CS..EExtended strand (participates in β ladder)trans-114.1136.2179.4-560000110.2A566 K567 Q587 W592 S593A566-T585 CarbonylContact O-C 3.55Å; A566-T585 VanDerWaalsContact O-CA 3.29Å; A566-T585 WeakPolarHBondContact O-CA 3.35Å; K567-T585 HydrophobicContact CG-CG2 4.28Å; T585-Q587 PolarHBondContact O-N 2.87Å; T585-W592 VanDerWaalsContact C-CE3 3.45Å; T585-S593 PolarHBondContact N-OG 2.94Å; T585-S593 PolarHBondContact O-N 2.82Å; T585-S593 PolarHBondContact O-OG 3.33Å
586C98.1Very high96.9Very high2 Ų275.6 Ų75.61%0.01439%0.39CS..BIsolated β-bridgetrans-73.4118.7175177.30000110.7C546 Y562 L563 Q564 G565 A566 W592C546-C586 HydrophobicContact CB-CB 3.72Å; C546-C586 WeakPolarHBondContact CB-SG 3.31Å; C546-C586 PolarHBondContact N-SG 3.08Å; C546-C586 VanDerWaalsContact N-SG 3.4Å; C546-C586 WeakPolarHBondContact SG-CA 3.22Å; C546-C586 WeakPolarHBondContact SG-CB 3.47Å; C546-C586 CovalentContact SG-SG 2.02Å; C546-C586 PolarHBondContact SG-SG 2.89Å; Y562-C586 PolarHBondContact O-SG 3.43Å; L563-C586 VanDerWaalsContact C-SG 3.56Å; L563-C586 WeakPolarHBondContact O-CB 3.31Å; Q564-C586 VanDerWaalsContact CA-SG 3.58Å; G565-C586 PolarHBondContact N-O 3.3Å; A566-C586 PolarHBondContact O-N 3.17Å; C586-W592 HydrophobicContact CB-CD2 4.49Å; C586-W592 HydrophobicContact CB-CE3 4.18Å; C586-W592 HydrophobicContact CB-CH2 3.76Å; C586-W592 HydrophobicContact CB-CZ2 4.05Å; C586-W592 HydrophobicContact CB-CZ3 3.84Å; C586-W592 VanDerWaalsContact N-CZ3 3.29Å
587Q98.1Very high97Very high88 Ų8872.7 Ų72.741%0.41138%0.383SS..  trans-94.4165.3-173.7-57.7-177.1-48.500112.2C546 T585 N589 G590 K591C546-Q587 PolarHBondContact SG-N 2.97Å; T585-Q587 PolarHBondContact O-N 2.87Å; Q587-N589 WeakPolarHBondContact CB-OD1 3.36Å; Q587-N589 PolarHBondContact O-N 3.32Å; Q587-N589 VanDerWaalsContact O-N 3.08Å; Q587-G590 PolarHBondContact O-N 3.33Å; Q587-K591 WeakPolarHBondContact CB-O 2.95Å; Q587-K591 PolarHBondContact N-O 3.43Å
588R97Very high97.1Very high205 Ų20568.6 Ų68.677%0.77437%0.372SS*.THydrogen-bonded Turntrans-60.1-17.2177.9-70.8-176.4-178.1150.4-0.6114.7I544 Q564 G590I544-R588 VanDerWaalsContact CD1-O 3.26Å; I544-R588 WeakPolarHBondContact CD1-O 3.41Å; Q564-R588 HydrophobicContact CG-CG 4.34Å; R588-G590 VanDerWaalsContact C-N 3.28Å
589N95.9Very high97.1Very high100 Ų10067 Ų6754%0.53537%0.365SS..THydrogen-bonded Turntrans-88.37177.264.32.5000112.8Q587 K591Q587-N589 WeakPolarHBondContact CB-OD1 3.36Å; Q587-N589 PolarHBondContact O-N 3.32Å; Q587-N589 VanDerWaalsContact O-N 3.08Å; N589-K591 VanDerWaalsContact C-N 3.28Å; N589-K591 PolarHBondContact O-N 2.88Å; N589-K591 WeakPolarHBondContact OD1-CB 3.34Å; N589-K591 PolarHBondContact OD1-N 2.87Å
590G95.8Very high97Very high25 Ų2566.9 Ų66.926%0.25836%0.364SS..SBendtrans72.118.6-176.900000114.1C546 Q587 R588C546-G590 WeakPolarHBondContact CA-O 3.3Å; Q587-G590 PolarHBondContact O-N 3.33Å; R588-G590 VanDerWaalsContact C-N 3.28Å
591K97Very high96.6Very high141 Ų14168.7 Ų68.761%0.61337%0.368SS*.  trans-119.5150.5177.2-59.7-177.3178.8-178.90111.6C546 Q587 N589C546-K591 VanDerWaalsContact SG-C 3.52Å; C546-K591 PolarHBondContact SG-N 2.85Å; C546-K591 PolarHBondContact SG-O 3.27Å; C546-K591 VanDerWaalsContact SG-O 3.36Å; Q587-K591 WeakPolarHBondContact CB-O 2.95Å; Q587-K591 PolarHBondContact N-O 3.43Å; N589-K591 VanDerWaalsContact C-N 3.28Å; N589-K591 PolarHBondContact O-N 2.88Å; N589-K591 WeakPolarHBondContact OD1-CB 3.34Å; N589-K591 PolarHBondContact OD1-N 2.87Å
592W97.9Very high95.7Very high23 Ų2369.8 Ų69.89%0.08738%0.375CS..BIsolated β-bridgetrans-74.2137.7170.9-70.4101.1000111C546 G547 L549 Y562 A566 V568 R584 T585 C586C546-W592 HydrophobicContact CB-CD2 3.97Å; C546-W592 VanDerWaalsContact CB-CE2 3.44Å; C546-W592 HydrophobicContact CB-CG 4.05Å; C546-W592 HydrophobicContact CB-CZ2 3.83Å; C546-W592 VanDerWaalsContact CB-NE1 3.27Å; C546-W592 PolarHBondContact O-NE1 3.35Å; G547-W592 PolarHBondContact O-NE1 3.2Å; L549-W592 HydrophobicContact CD1-CB 4.3Å; L549-W592 HydrophobicContact CD1-CD2 3.6Å; L549-W592 HydrophobicContact CD1-CE3 4.1Å; L549-W592 HydrophobicContact CD1-CG 3.65Å; L549-W592 HydrophobicContact CD2-CG 4.11Å; L549-W592 HydrophobicContact CG-CD2 4.15Å; L549-W592 HydrophobicContact CG-CG 4.05Å; Y562-W592 HydrophobicContact CD1-CH2 4.28Å; Y562-W592 AromaticContact CD1-CZ2 3.7Å; Y562-W592 HydrophobicContact CD1-CZ2 3.7Å; Y562-W592 HydrophobicContact CG-CZ2 4.47Å; A566-W592 HydrophobicContact CB-CH2 4.3Å; A566-W592 WeakPolarHBondContact O-CZ3 3.43Å; V568-W592 HydrophobicContact CB-CZ3 4.29Å; V568-W592 HydrophobicContact CG2-CH2 3.62Å; V568-W592 HydrophobicContact CG2-CZ2 4.33Å; V568-W592 HydrophobicContact CG2-CZ3 3.83Å; R584-W592 HydrophobicContact CB-CB 4.44Å; R584-W592 HydrophobicContact CB-CE3 3.89Å; R584-W592 WeakPolarHBondContact O-CZ3 3.02Å; T585-W592 VanDerWaalsContact C-CE3 3.45Å; C586-W592 HydrophobicContact CB-CD2 4.49Å; C586-W592 HydrophobicContact CB-CE3 4.18Å; C586-W592 HydrophobicContact CB-CH2 3.76Å; C586-W592 HydrophobicContact CB-CZ2 4.05Å; C586-W592 HydrophobicContact CB-CZ3 3.84Å; C586-W592 VanDerWaalsContact N-CZ3 3.29Å
593S98.3Very high94.2Very high27 Ų2768.5 Ų68.519%0.18938%0.38CS..  trans-67.3161.7171.869.80000111.9R584 T585R584-S593 WeakPolarHBondContact CG-O 3.45Å; R584-S593 PolarHBondContact NE-O 3.45Å; T585-S593 PolarHBondContact N-OG 2.94Å; T585-S593 PolarHBondContact O-N 2.82Å; T585-S593 PolarHBondContact O-OG 3.33Å
594G96.8Very high92.5Very high50 Ų5073.3 Ų73.352%0.51540%0.4SS..SBendtrans68.6-167.6171.500000114.3S581 R584S581-G594 WeakPolarHBondContact OG-CA 3.41Å; R584-G594 PolarHBondContact NH2-O 3.45Å
595E97Very high90.7Very high140 Ų14075.9 Ų75.965%0.65442%0.417SS*.  trans-105.3155.4-173.4-62.9178.8173.700111.5S581 A597S581-E595 WeakPolarHBondContact CB-O 3.22Å; S581-E595 PolarHBondContact N-O 2.93Å; S581-E595 PolarHBondContact OG-N 2.89Å; E595-A597 PolarHBondContact O-N 2.71Å
596D95.9Very high88.7Confident121 Ų12177.2 Ų77.265%0.64743%0.433SS*.  trans-61.5134.2178.5-67.5-17.9000111.3R584R584-D596 IonicContact CZ-OD1 2.77Å; R584-D596 IonicContact NH1-OD1 3.26Å; R584-D596 PolarHBondContact NH1-OD1 3.18Å; R584-D596 IonicContact NH2-OD1 2.71Å; R584-D596 PolarHBondContact NH2-OD1 2.96Å
597A96.4Very high86.9Confident20 Ų2079.4 Ų79.417%0.16546%0.455CS..  trans-78.3135.317900000110.9F570 L578 S579 E595F570-A597 HydrophobicContact CB-CB 3.68Å; F570-A597 HydrophobicContact CD1-CB 4.13Å; F570-A597 HydrophobicContact CD2-CB 3.81Å; F570-A597 HydrophobicContact CE2-CB 4.5Å; F570-A597 HydrophobicContact CG-CB 3.59Å; L578-A597 HydrophobicContact CD1-CB 3.96Å; S579-A597 CarbonylContact O-C 3.57Å; S579-A597 WeakPolarHBondContact O-CA 3.47Å; E595-A597 PolarHBondContact O-N 2.71Å
598S96.7Very high85.2Confident57 Ų5780.6 Ų80.640%0.39946%0.463SS..EExtended strand (participates in β ladder)trans-138.8147.5172.661.50000111.1L578 S579L578-S598 CarbonylContact C-O 3.51Å; L578-S598 WeakPolarHBondContact CA-O 3.34Å; S579-S598 PolarHBondContact N-O 2.86Å; S579-S598 PolarHBondContact O-N 3.3Å
599C96.3Very high83.6Confident17 Ų1774.8 Ų74.812%0.11545%0.451CS..EExtended strand (participates in β ladder)trans-114.8125-180-64.80000109.5A553 N554 C572 Y576A553-C599 WeakPolarHBondContact O-CB 3.38Å; N554-C599 WeakPolarHBondContact O-CB 3.32Å; C572-C599 WeakPolarHBondContact CA-SG 3.24Å; C572-C599 HydrophobicContact CB-CB 3.71Å; C572-C599 WeakPolarHBondContact CB-SG 3.42Å; C572-C599 WeakPolarHBondContact SG-CA 3.49Å; C572-C599 WeakPolarHBondContact SG-CB 3.19Å; C572-C599 CovalentContact SG-SG 2.03Å; C572-C599 PolarHBondContact SG-SG 3.07Å; Y576-C599 HydrophobicContact CD1-CB 4.39Å; Y576-C599 HydrophobicContact CG-CB 4.5Å
600S93.9Very high82.1Confident64 Ų6472.7 Ų72.745%0.44845%0.447SS..EExtended strand (participates in β ladder)trans-137.6151.4-178.3610000111.5K577K577-S600 PolarHBondContact N-O 2.69Å; K577-S600 PolarHBondContact O-N 3.46Å; K577-S600 VanDerWaalsContact O-N 3.11Å
601V87.8Confident80.8Confident73 Ų7373.7 Ų73.744%0.44246%0.457SS..  trans-67.5133177.5-174.30000109.1Y576 S603 V605Y576-V601 HydrophobicContact CD1-CG2 4.15Å; Y576-V601 HydrophobicContact CE1-CG2 3.75Å; V601-S603 PolarHBondContact O-N 2.82Å; V601-V605 HydrophobicContact CG1-CB 4.02Å; V601-V605 HydrophobicContact CG1-CG1 4.47Å; V601-V605 HydrophobicContact CG1-CG2 4.32Å
602P78.3Confident79.7Confident53 Ų5370.3 Ų70.334%0.34445%0.452SS..  trans-55.2128.7175.2-23.431.4000111.5D575 K577 K604 V605D575-P602 WeakPolarHBondContact O-CD 3.21Å; K577-P602 HydrophobicContact CB-CG 4.3Å; P602-K604 PolarHBondContact O-N 2.92Å; P602-V605 PolarHBondContact O-N 2.92Å
603S65.9Low78.8Confident105 Ų10573.1 Ų73.173%0.73447%0.471SS*.Hα-helixtrans-53.4-19.1-174.4590000115.7V601 V605 G607V601-S603 PolarHBondContact O-N 2.82Å; S603-V605 VanDerWaalsContact C-N 3.32Å; S603-V605 PolarHBondContact O-N 2.81Å; S603-G607 PolarHBondContact O-N 2.98Å
604K63.4Low78Confident169 Ų16976.1 Ų76.174%0.73549%0.488SS*.Hα-helixtrans-66.1-30.5176.7-64-173.1178.8-177.20113P602 I608P602-K604 PolarHBondContact O-N 2.92Å; K604-I608 WeakPolarHBondContact O-CD1 3.2Å; K604-I608 VanDerWaalsContact O-CG1 3.25Å; K604-I608 WeakPolarHBondContact O-CG1 3.29Å; K604-I608 PolarHBondContact O-N 2.97Å; K604-I608 VanDerWaalsContact O-N 3.09Å
605V59Low77.3Confident73 Ų7375.3 Ų75.344%0.44248%0.479SS..Hα-helixtrans-75.2-41.7-178.3-177.30000111.3V601 P602 S603 G607 I608 V609V601-V605 HydrophobicContact CG1-CB 4.02Å; V601-V605 HydrophobicContact CG1-CG1 4.47Å; V601-V605 HydrophobicContact CG1-CG2 4.32Å; P602-V605 PolarHBondContact O-N 2.92Å; S603-V605 VanDerWaalsContact C-N 3.32Å; S603-V605 PolarHBondContact O-N 2.81Å; V605-G607 VanDerWaalsContact C-N 3.27Å; V605-G607 PolarHBondContact O-N 3.34Å; V605-I608 PolarHBondContact O-N 3.35Å; V605-I608 VanDerWaalsContact O-N 3.15Å; V605-V609 HydrophobicContact CG1-CG2 4.42Å; V605-V609 WeakPolarHBondContact O-CG2 3.26Å; V605-V609 PolarHBondContact O-N 3.43Å
606A56.7Low76.7Confident69 Ų6971.2 Ų71.257%0.5747%0.47SS*.Hα-helixtrans-59.8-39.1173.500000111.9A610A606-A610 VanDerWaalsContact O-CB 3.25Å; A606-A610 WeakPolarHBondContact O-CB 3.42Å; A606-A610 PolarHBondContact O-N 2.9Å
607G60.1Low76.3Confident47 Ų4770.3 Ų70.349%0.48546%0.464SS..Hα-helixtrans-65.7-38.1174.200000113.7S603 V605 G611S603-G607 PolarHBondContact O-N 2.98Å; V605-G607 VanDerWaalsContact C-N 3.27Å; V605-G607 PolarHBondContact O-N 3.34Å; G607-G611 PolarHBondContact O-N 3.37Å
608I63.7Low75.8Confident113 Ų11372.8 Ų72.858%0.57948%0.478SS*.Hα-helixtrans-70.1-42.5176.5-68.3163.2000110.9K604 V605 G611 S612K604-I608 WeakPolarHBondContact O-CD1 3.2Å; K604-I608 VanDerWaalsContact O-CG1 3.25Å; K604-I608 WeakPolarHBondContact O-CG1 3.29Å; K604-I608 PolarHBondContact O-N 2.97Å; K604-I608 VanDerWaalsContact O-N 3.09Å; V605-I608 PolarHBondContact O-N 3.35Å; V605-I608 VanDerWaalsContact O-N 3.15Å; I608-G611 PolarHBondContact O-N 3.25Å; I608-S612 VanDerWaalsContact O-CB 3.3Å; I608-S612 WeakPolarHBondContact O-CB 3.4Å; I608-S612 PolarHBondContact O-N 3.22Å; I608-S612 PolarHBondContact O-OG 3.07Å
609V63.8Low75.4Confident84 Ų8475.2 Ų75.251%0.50949%0.486SS..Hα-helixtrans-64.8-47.5177175.10000110.5V605 G611 S612 V613V605-V609 HydrophobicContact CG1-CG2 4.42Å; V605-V609 WeakPolarHBondContact O-CG2 3.26Å; V605-V609 PolarHBondContact O-N 3.43Å; V609-G611 PolarHBondContact O-N 2.95Å; V609-S612 PolarHBondContact O-N 3Å; V609-V613 WeakPolarHBondContact O-CG2 3.46Å; V609-V613 PolarHBondContact O-N 3.27Å
610A63.7Low75.1Confident56 Ų5679.2 Ų79.246%0.46351%0.505SS..Hα-helixtrans-60.9-44175.200000111.8A606 S612 V613 V614A606-A610 VanDerWaalsContact O-CB 3.25Å; A606-A610 WeakPolarHBondContact O-CB 3.42Å; A606-A610 PolarHBondContact O-N 2.9Å; A610-S612 VanDerWaalsContact C-N 3.34Å; A610-S612 PolarHBondContact O-N 3.23Å; A610-V613 PolarHBondContact O-N 3.37Å; A610-V614 WeakPolarHBondContact O-CB 3.13Å; A610-V614 VanDerWaalsContact O-CG2 3.27Å; A610-V614 WeakPolarHBondContact O-CG2 3.31Å; A610-V614 PolarHBondContact O-N 2.75Å
611G68.9Low74.9Confident45 Ų4580.7 Ų80.746%0.46451%0.511SS..Hα-helixtrans-62.9-37.3176.300000113.2G607 I608 V609 G615G607-G611 PolarHBondContact O-N 3.37Å; I608-G611 PolarHBondContact O-N 3.25Å; V609-G611 PolarHBondContact O-N 2.95Å; G611-G615 PolarHBondContact O-N 3.11Å
612S73Confident75Confident71 Ų7181.9 Ų81.950%0.49751%0.514SS..Hα-helixtrans-69.9-40.2177.7-56.30000112I608 V609 A610 G615 A616I608-S612 VanDerWaalsContact O-CB 3.3Å; I608-S612 WeakPolarHBondContact O-CB 3.4Å; I608-S612 PolarHBondContact O-N 3.22Å; I608-S612 PolarHBondContact O-OG 3.07Å; V609-S612 PolarHBondContact O-N 3Å; A610-S612 VanDerWaalsContact C-N 3.34Å; A610-S612 PolarHBondContact O-N 3.23Å; S612-G615 PolarHBondContact O-N 3.28Å; S612-A616 WeakPolarHBondContact O-CB 3.33Å; S612-A616 PolarHBondContact O-N 3.25Å
613V79.8Confident75.5Confident82 Ų8283.3 Ų83.350%0.49752%0.518SS..Hα-helixtrans-66.5-45.4175.6173.20000110.9V609 A610 G615 A616 L617V609-V613 WeakPolarHBondContact O-CG2 3.46Å; V609-V613 PolarHBondContact O-N 3.27Å; A610-V613 PolarHBondContact O-N 3.37Å; V613-G615 VanDerWaalsContact C-N 3.33Å; V613-G615 PolarHBondContact O-N 3.5Å; V613-A616 PolarHBondContact O-N 3.07Å; V613-L617 HydrophobicContact CG1-CD1 3.98Å; V613-L617 WeakPolarHBondContact O-CB 3.13Å; V613-L617 VanDerWaalsContact O-CG 3.31Å; V613-L617 WeakPolarHBondContact O-CG 3.09Å; V613-L617 PolarHBondContact O-N 2.93Å
614V81.4Confident76.5Confident89 Ų8981.7 Ų81.754%0.53950%0.503SS..Hα-helixtrans-63.9-39.9175.4174.10000110.9A610 L617 T618A610-V614 WeakPolarHBondContact O-CB 3.13Å; A610-V614 VanDerWaalsContact O-CG2 3.27Å; A610-V614 WeakPolarHBondContact O-CG2 3.31Å; A610-V614 PolarHBondContact O-N 2.75Å; V614-L617 PolarHBondContact O-N 2.84Å; V614-T618 HydrophobicContact CG1-CG2 4.44Å; V614-T618 WeakPolarHBondContact O-CB 3.34Å; V614-T618 VanDerWaalsContact O-CG2 3.31Å; V614-T618 WeakPolarHBondContact O-CG2 3.22Å; V614-T618 PolarHBondContact O-N 2.65Å; V614-T618 PolarHBondContact O-OG1 3.2Å
615G81.8Confident77.6Confident33 Ų3376.2 Ų76.234%0.3449%0.489SS..Hα-helixtrans-61.8-44.9174.500000112.7G611 S612 V613 T618 L619G611-G615 PolarHBondContact O-N 3.11Å; S612-G615 PolarHBondContact O-N 3.28Å; V613-G615 VanDerWaalsContact C-N 3.33Å; V613-G615 PolarHBondContact O-N 3.5Å; G615-T618 WeakPolarHBondContact CA-OG1 3.48Å; G615-T618 PolarHBondContact O-N 3.26Å; G615-T618 PolarHBondContact O-OG1 3.47Å; G615-L619 WeakPolarHBondContact O-CB 3.39Å; G615-L619 PolarHBondContact O-N 3.39Å
616A84.7Confident78.9Confident54 Ų5478 Ų7845%0.44650%0.496SS..Hα-helixtrans-65.4-43.4177.500000112.1S612 V613 L619 I620S612-A616 WeakPolarHBondContact O-CB 3.33Å; S612-A616 PolarHBondContact O-N 3.25Å; V613-A616 PolarHBondContact O-N 3.07Å; A616-L619 PolarHBondContact O-N 3.29Å; A616-I620 VanDerWaalsContact O-CG1 3.31Å; A616-I620 WeakPolarHBondContact O-CG1 3.12Å; A616-I620 PolarHBondContact O-N 3.48Å
617L87.3Confident80.3Confident103 Ų10378.4 Ų78.454%0.53949%0.488SS..Hα-helixtrans-63.7-42.2177.2-72.7170.3000112V613 V614 I620 V621V613-L617 HydrophobicContact CG1-CD1 3.98Å; V613-L617 WeakPolarHBondContact O-CB 3.13Å; V613-L617 VanDerWaalsContact O-CG 3.31Å; V613-L617 WeakPolarHBondContact O-CG 3.09Å; V613-L617 PolarHBondContact O-N 2.93Å; V614-L617 PolarHBondContact O-N 2.84Å; L617-I620 PolarHBondContact O-N 2.85Å; L617-V621 WeakPolarHBondContact O-CG2 3.41Å; L617-V621 PolarHBondContact O-N 3.36Å; L617-V621 VanDerWaalsContact O-N 3.09Å
618T86.3Confident81.4Confident72 Ų7281.6 Ų81.644%0.44249%0.493SS..Hα-helixtrans-65.5-38.8176.349.90000111.8V614 G615 I620 V621 I622V614-T618 HydrophobicContact CG1-CG2 4.44Å; V614-T618 WeakPolarHBondContact O-CB 3.34Å; V614-T618 VanDerWaalsContact O-CG2 3.31Å; V614-T618 WeakPolarHBondContact O-CG2 3.22Å; V614-T618 PolarHBondContact O-N 2.65Å; V614-T618 PolarHBondContact O-OG1 3.2Å; G615-T618 WeakPolarHBondContact CA-OG1 3.48Å; G615-T618 PolarHBondContact O-N 3.26Å; G615-T618 PolarHBondContact O-OG1 3.47Å; T618-I620 PolarHBondContact O-N 2.75Å; T618-V621 PolarHBondContact O-N 3.08Å; T618-I622 VanDerWaalsContact O-CG1 3.31Å; T618-I622 WeakPolarHBondContact O-CG1 2.94Å; T618-I622 PolarHBondContact O-N 2.83Å
619L88.3Confident82.2Confident108 Ų10881.5 Ų81.557%0.56549%0.49SS*.Hα-helixtrans-62.7-42.6175.4-142.899.3000112.1G615 A616 V621 I622 I623G615-L619 WeakPolarHBondContact O-CB 3.39Å; G615-L619 PolarHBondContact O-N 3.39Å; A616-L619 PolarHBondContact O-N 3.29Å; L619-V621 VanDerWaalsContact C-N 3.33Å; L619-V621 PolarHBondContact O-N 3.18Å; L619-I622 PolarHBondContact O-N 3.04Å; L619-I623 HydrophobicContact CD2-CD1 3.98Å; L619-I623 HydrophobicContact CG-CD1 4.43Å; L619-I623 WeakPolarHBondContact O-CB 3.41Å; L619-I623 VanDerWaalsContact O-CG1 3.27Å; L619-I623 WeakPolarHBondContact O-CG1 3.26Å; L619-I623 PolarHBondContact O-N 3.45Å
620I89.8Confident82.8Confident101 Ų10180.3 Ų80.352%0.51849%0.485SS..Hα-helixtrans-61.3-42.8176.5-69.7166.1000110.8A616 L617 T618 I623 T624A616-I620 VanDerWaalsContact O-CG1 3.31Å; A616-I620 WeakPolarHBondContact O-CG1 3.12Å; A616-I620 PolarHBondContact O-N 3.48Å; L617-I620 PolarHBondContact O-N 2.85Å; T618-I620 PolarHBondContact O-N 2.75Å; I620-I623 PolarHBondContact O-N 3.13Å; I620-T624 PolarHBondContact O-N 3.17Å; I620-T624 PolarHBondContact O-OG1 2.83Å
621V89.8Confident83.5Confident95 Ų9586 Ų8658%0.57650%0.495SS*.Hα-helixtrans-63.7-42.2176.9173.10000111.3L617 T618 L619 T624 A625L617-V621 WeakPolarHBondContact O-CG2 3.41Å; L617-V621 PolarHBondContact O-N 3.36Å; L617-V621 VanDerWaalsContact O-N 3.09Å; T618-V621 PolarHBondContact O-N 3.08Å; L619-V621 VanDerWaalsContact C-N 3.33Å; L619-V621 PolarHBondContact O-N 3.18Å; V621-T624 VanDerWaalsContact CA-OG1 3.3Å; V621-T624 WeakPolarHBondContact CA-OG1 3.36Å; V621-T624 PolarHBondContact O-N 3.29Å; V621-T624 PolarHBondContact O-OG1 2.96Å; V621-T624 VanDerWaalsContact O-OG1 3.07Å; V621-A625 VanDerWaalsContact O-CB 3.29Å; V621-A625 WeakPolarHBondContact O-CB 3.49Å; V621-A625 PolarHBondContact O-N 3.01Å
622I89.4Confident83.8Confident98 Ų9890.9 Ų90.950%0.50350%0.503SS..Hα-helixtrans-64.2-46.1176.7-68.3166.6000110.6T618 L619 T624 A625 L626T618-I622 VanDerWaalsContact O-CG1 3.31Å; T618-I622 WeakPolarHBondContact O-CG1 2.94Å; T618-I622 PolarHBondContact O-N 2.83Å; L619-I622 PolarHBondContact O-N 3.04Å; I622-T624 PolarHBondContact O-N 2.79Å; I622-A625 PolarHBondContact O-N 3.31Å; I622-L626 HydrophobicContact CG2-CD1 4.03Å; I622-L626 HydrophobicContact CG2-CG 4.47Å; I622-L626 WeakPolarHBondContact O-CG 3.07Å; I622-L626 PolarHBondContact O-N 3.01Å
623I89.2Confident83.7Confident83 Ų8393.4 Ų93.443%0.42651%0.507SS..Hα-helixtrans-62.7-44.7178.7-69.4167.5000110.6L619 I620 A625 L626 I627L619-I623 HydrophobicContact CD2-CD1 3.98Å; L619-I623 HydrophobicContact CG-CD1 4.43Å; L619-I623 WeakPolarHBondContact O-CB 3.41Å; L619-I623 VanDerWaalsContact O-CG1 3.27Å; L619-I623 WeakPolarHBondContact O-CG1 3.26Å; L619-I623 PolarHBondContact O-N 3.45Å; I620-I623 PolarHBondContact O-N 3.13Å; I623-A625 PolarHBondContact O-N 2.93Å; I623-L626 PolarHBondContact O-N 3.1Å; I623-I627 HydrophobicContact CG2-CD1 3.78Å; I623-I627 HydrophobicContact CG2-CG1 4.42Å; I623-I627 VanDerWaalsContact O-CG1 3.27Å; I623-I627 WeakPolarHBondContact O-CG1 3.37Å; I623-I627 PolarHBondContact O-N 3.5Å
624T86.7Confident83.1Confident70 Ų7097.4 Ų97.443%0.42952%0.518SS..Hα-helixtrans-64.1-4017633.60000111.9I620 V621 I622 L626 I627 L628I620-T624 PolarHBondContact O-N 3.17Å; I620-T624 PolarHBondContact O-OG1 2.83Å; V621-T624 VanDerWaalsContact CA-OG1 3.3Å; V621-T624 WeakPolarHBondContact CA-OG1 3.36Å; V621-T624 PolarHBondContact O-N 3.29Å; V621-T624 PolarHBondContact O-OG1 2.96Å; V621-T624 VanDerWaalsContact O-OG1 3.07Å; I622-T624 PolarHBondContact O-N 2.79Å; T624-L626 PolarHBondContact O-N 3.45Å; T624-I627 PolarHBondContact O-N 2.74Å; T624-L628 WeakPolarHBondContact O-CB 3.45Å; T624-L628 VanDerWaalsContact O-CG 3.23Å; T624-L628 WeakPolarHBondContact O-CG 3.27Å; T624-L628 PolarHBondContact O-N 2.58Å
625A86.1Confident82.1Confident54 Ų54102.2 Ų102.245%0.44653%0.526SS..Hα-helixtrans-61.9-41.817400000112.2V621 I622 I623 L628 H629V621-A625 VanDerWaalsContact O-CB 3.29Å; V621-A625 WeakPolarHBondContact O-CB 3.49Å; V621-A625 PolarHBondContact O-N 3.01Å; I622-A625 PolarHBondContact O-N 3.31Å; I623-A625 PolarHBondContact O-N 2.93Å; A625-L628 PolarHBondContact O-N 2.86Å; A625-H629 VanDerWaalsContact O-CB 3.29Å; A625-H629 WeakPolarHBondContact O-CB 3.31Å; A625-H629 PolarHBondContact O-N 2.85Å
626L86.7Confident81.1Confident110 Ų110108.1 Ų108.158%0.57654%0.543SS*.Hα-helixtrans-65.2-40.4174.9-72.3171000112.1I622 I623 T624 H629 S630I622-L626 HydrophobicContact CG2-CD1 4.03Å; I622-L626 HydrophobicContact CG2-CG 4.47Å; I622-L626 WeakPolarHBondContact O-CG 3.07Å; I622-L626 PolarHBondContact O-N 3.01Å; I623-L626 PolarHBondContact O-N 3.1Å; T624-L626 PolarHBondContact O-N 3.45Å; L626-H629 PolarHBondContact O-N 3.39Å; L626-S630 WeakPolarHBondContact O-CB 3.45Å; L626-S630 PolarHBondContact O-N 3.07Å; L626-S630 PolarHBondContact O-OG 3.44Å
627I85.3Confident79.8Confident78 Ų78108.4 Ų108.440%0.454%0.541SS..Hα-helixtrans-64.8-42.8174.6-68.8168.1000110.6I623 T624 S630 R631I623-I627 HydrophobicContact CG2-CD1 3.78Å; I623-I627 HydrophobicContact CG2-CG1 4.42Å; I623-I627 VanDerWaalsContact O-CG1 3.27Å; I623-I627 WeakPolarHBondContact O-CG1 3.37Å; I623-I627 PolarHBondContact O-N 3.5Å; T624-I627 PolarHBondContact O-N 2.74Å; I627-S630 WeakPolarHBondContact CA-OG 3.4Å; I627-S630 PolarHBondContact O-OG 2.81Å; I627-R631 WeakPolarHBondContact O-CB 3.37Å; I627-R631 WeakPolarHBondContact O-CG 3.21Å; I627-R631 PolarHBondContact O-N 3.03Å
628L82.9Confident78.3Confident114 Ų114106.4 Ų106.460%0.59754%0.536SS*.Hα-helixtrans-66.2-39.1176.2-71.2172.1000111.7T624 A625 R631 K632T624-L628 WeakPolarHBondContact O-CB 3.45Å; T624-L628 VanDerWaalsContact O-CG 3.23Å; T624-L628 WeakPolarHBondContact O-CG 3.27Å; T624-L628 PolarHBondContact O-N 2.58Å; A625-L628 PolarHBondContact O-N 2.86Å; L628-R631 PolarHBondContact O-N 3.18Å; L628-K632 WeakPolarHBondContact O-CB 3.49Å; L628-K632 PolarHBondContact O-N 3.22Å
629H80.6Confident76.8Confident112 Ų112107.8 Ų107.852%0.51954%0.54SS..Hα-helixtrans-67-44.3177.1-167.8-84.8000111.9A625 L626 K632 Q633A625-H629 VanDerWaalsContact O-CB 3.29Å; A625-H629 WeakPolarHBondContact O-CB 3.31Å; A625-H629 PolarHBondContact O-N 2.85Å; L626-H629 PolarHBondContact O-N 3.39Å; H629-K632 WeakPolarHBondContact O-CB 3.28Å; H629-K632 PolarHBondContact O-N 2.77Å; H629-Q633 PolarHBondContact O-N 3.41Å
630S77.3Confident75.1Confident58 Ų58105.7 Ų105.741%0.40654%0.535SS..Hα-helixtrans-65-38.217559.30000112.4L626 I627 Q633 K634L626-S630 WeakPolarHBondContact O-CB 3.45Å; L626-S630 PolarHBondContact O-N 3.07Å; L626-S630 PolarHBondContact O-OG 3.44Å; I627-S630 WeakPolarHBondContact CA-OG 3.4Å; I627-S630 PolarHBondContact O-OG 2.81Å; S630-Q633 PolarHBondContact O-N 2.76Å; S630-K634 PolarHBondContact O-N 2.99Å
631R77.7Confident73.4Confident176 Ų176106.2 Ų106.266%0.66454%0.539SS*.Hα-helixtrans-62.6-40.1170.4-80.1-179.7160.5174.3-4.2112.1I627 L628 K634 R635I627-R631 WeakPolarHBondContact O-CB 3.37Å; I627-R631 WeakPolarHBondContact O-CG 3.21Å; I627-R631 PolarHBondContact O-N 3.03Å; L628-R631 PolarHBondContact O-N 3.18Å; R631-K634 PolarHBondContact O-N 3.13Å; R631-R635 PolarHBondContact O-N 2.83Å
632K75.6Confident71.5Confident147 Ų147108 Ų10864%0.63954%0.541SS*.Hα-helixtrans-67-37.9176.4-165.8176.4-177.3178.70112L628 H629 R635 K636L628-K632 WeakPolarHBondContact O-CB 3.49Å; L628-K632 PolarHBondContact O-N 3.22Å; H629-K632 WeakPolarHBondContact O-CB 3.28Å; H629-K632 PolarHBondContact O-N 2.77Å; K632-R635 PolarHBondContact O-N 2.76Å; K632-K636 PolarHBondContact O-N 3.39Å
633Q70.4Confident69.7Low125 Ų125110.9 Ų110.958%0.58455%0.552SS**Hα-helixtrans-66.6-41.6173.1-82.5-173.3-29.500112.5H629 S630 R635 K636 S637H629-Q633 PolarHBondContact O-N 3.41Å; S630-Q633 PolarHBondContact O-N 2.76Å; Q633-R635 VanDerWaalsContact C-N 3.32Å; Q633-R635 PolarHBondContact O-N 3.28Å; Q633-K636 PolarHBondContact O-N 2.94Å; Q633-S637 PolarHBondContact O-N 3.48Å
634K67.1Low67.9Low165 Ų165116.7 Ų116.772%0.71757%0.569SS**Hα-helixtrans-62-36.7172.5-94.6-174.4173.2-177.20113.1S630 R631 S637 S638S630-K634 PolarHBondContact O-N 2.99Å; R631-K634 PolarHBondContact O-N 3.13Å; K634-S637 PolarHBondContact O-N 3.14Å; K634-S637 PolarHBondContact O-OG 3.27Å; K634-S637 VanDerWaalsContact O-OG 3.06Å; K634-S638 PolarHBondContact O-N 2.98Å
635R61.9Low66.3Low190 Ų190117.6 Ų117.672%0.71758%0.578SS**Hα-helixtrans-68.9-38.6175.6-125.2175.1177172.6-2.4112.3R631 K632 Q633 S637 S638 D639R631-R635 PolarHBondContact O-N 2.83Å; K632-R635 PolarHBondContact O-N 2.76Å; Q633-R635 VanDerWaalsContact C-N 3.32Å; Q633-R635 PolarHBondContact O-N 3.28Å; R635-S637 VanDerWaalsContact C-N 3.34Å; R635-S638 PolarHBondContact O-N 3.08Å; R635-S638 PolarHBondContact O-OG 2.84Å; R635-S638 VanDerWaalsContact O-OG 3.04Å; R635-D639 PolarHBondContact O-N 2.8Å
636K59.4Low64.7Low158 Ų158122 Ų12269%0.68759%0.594SS**Hα-helixtrans-66.2-33.4172.7-101.7-174.6171.9-171.30113K632 Q633 S640K632-K636 PolarHBondContact O-N 3.39Å; Q633-K636 PolarHBondContact O-N 2.94Å; K636-S640 PolarHBondContact O-N 3.45Å; K636-S640 PolarHBondContact O-OG 3.18Å
637S57.4Low63.1Low60 Ų60122.5 Ų122.542%0.4260%0.602SS.*Hα-helixtrans-73.9-33.217580.50000112.3Q633 K634 R635 S640 D641Q633-S637 PolarHBondContact O-N 3.48Å; K634-S637 PolarHBondContact O-N 3.14Å; K634-S637 PolarHBondContact O-OG 3.27Å; K634-S637 VanDerWaalsContact O-OG 3.06Å; R635-S637 VanDerWaalsContact C-N 3.34Å; S637-S640 WeakPolarHBondContact CA-OG 3.34Å; S637-S640 PolarHBondContact O-OG 3.3Å; S637-D641 PolarHBondContact O-N 2.8Å
638S56.1Low61.5Low60 Ų60123.7 Ų123.742%0.4262%0.617SS.*Hα-helixtrans-71.8-38.5174.673.40000112.7K634 R635 S640 D641 E642K634-S638 PolarHBondContact O-N 2.98Å; R635-S638 PolarHBondContact O-N 3.08Å; R635-S638 PolarHBondContact O-OG 2.84Å; R635-S638 VanDerWaalsContact O-OG 3.04Å; S638-S640 VanDerWaalsContact C-N 3.33Å; S638-S640 PolarHBondContact O-N 3.45Å; S638-D641 PolarHBondContact O-N 3.35Å; S638-E642 PolarHBondContact O-N 2.95Å; S638-E642 VanDerWaalsContact O-N 3.07Å
639D54.8Low60Low101 Ų101127.7 Ų127.754%0.5463%0.63SS.*Hα-helixtrans-64.1-36.6174.2-85.9-13.9000111.8R635 D641 E642 E643R635-D639 PolarHBondContact O-N 2.8Å; D639-D641 VanDerWaalsContact C-N 3.3Å; D639-D641 PolarHBondContact O-N 2.92Å; D639-E642 PolarHBondContact O-N 2.61Å; D639-E643 PolarHBondContact O-N 3.08Å
640S53.2Low58Low64 Ų64134.1 Ų134.145%0.44867%0.667SS.*Hα-helixtrans-70.7-22.9176.157.60000114.3K636 S637 S638K636-S640 PolarHBondContact O-N 3.45Å; K636-S640 PolarHBondContact O-OG 3.18Å; S637-S640 WeakPolarHBondContact CA-OG 3.34Å; S637-S640 PolarHBondContact O-OG 3.3Å; S638-S640 VanDerWaalsContact C-N 3.33Å; S638-S640 PolarHBondContact O-N 3.45Å
641D53Low57.1Low113 Ų113138 Ų13860%0.60468%0.68SS**Hα-helixtrans-85.2-27.8174.8-75.5-26.9000111.9S637 S638 D639S637-D641 PolarHBondContact O-N 2.8Å; S638-D641 PolarHBondContact O-N 3.35Å; D639-D641 VanDerWaalsContact C-N 3.3Å; D639-D641 PolarHBondContact O-N 2.92Å
642E51.4Low56Low133 Ų133135.9 Ų135.962%0.62168%0.681SS**Hα-helixtrans-78.4-32.4175.8-158.3165.2-173.100112.3S638 D639 R644 S645S638-E642 PolarHBondContact O-N 2.95Å; S638-E642 VanDerWaalsContact O-N 3.07Å; D639-E642 PolarHBondContact O-N 2.61Å; E642-R644 VanDerWaalsContact C-N 3.29Å; E642-R644 PolarHBondContact O-N 3.12Å; E642-S645 PolarHBondContact O-N 2.79Å
643E51.1Low54.9Low158 Ų158135.3 Ų135.374%0.73868%0.683SS**THydrogen-bonded Turntrans-70.9-22.9173.8-141.2172-160.800112.7D639D639-E643 PolarHBondContact O-N 3.08Å
644R51.1Low54Low205 Ų205135.9 Ų135.977%0.77469%0.689SS**THydrogen-bonded Turntrans-83.2-14.6176.7-138.4173.1-172.8-172.90.8113.8E642E642-R644 VanDerWaalsContact C-N 3.29Å; E642-R644 PolarHBondContact O-N 3.12Å
645S52.5Low53.2Low88 Ų88134.1 Ų134.162%0.61569%0.687SS**THydrogen-bonded Turntrans-87-25.3177.9-171.80000113.1E642E642-S645 PolarHBondContact O-N 2.79Å
646N52.9Low52.6Low146 Ų146130.4 Ų130.478%0.78169%0.685SS**THydrogen-bonded Turntrans-90.82.4-176.4-96.5-18.1000115.8
647T52.8Low52.1Low121 Ų121128.4 Ų128.474%0.74269%0.685SS**THydrogen-bonded Turntrans-101.312176.728.70000115.4
648S51.9Low51.7Low104 Ų104133.7 Ų133.773%0.72771%0.705SS**SBendtrans-115.726.8176.7102.50000115.6
649K51.8Low51.3Low197 Ų197139.8 Ų139.886%0.85773%0.729SS**  trans-122.981.1163.3-82.1-173.6178.8176.70110.3
650L39.4Very low51Low248 Ų248143.4 Ų143.4100%1.29875%0.746SS**  trans-165.50144.8-107.6149.2000109.2

Retrieved 650 of 650 residues in 593.5 ms (Link to these results)