A0A087YPS6_POEFO Loading...

Alpha-2A adrenergic receptor

AlphaFold DB , UniProt , Accession A0A087YPS6, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 422 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	35.7	Very low	38.1	Very low	249 Å²	249	151.8 Å²	151.8	100%	1.227	83%	0.828	S	S	*	*				0	120.1	0	-111.5	169.5	-179.5	0	0	107.4
2	A	37.1	Very low	38.7	Very low	97 Å²	97	147.1 Å²	147.1	80%	0.802	81%	0.811	S	S	*	*			trans	70	93.2	171.5	0	0	0	0	0	118.8
3	D	36.3	Very low	39.3	Very low	149 Å²	149	145.1 Å²	145.1	80%	0.797	81%	0.813	S	S	*	*			trans	-62.2	127.2	153.9	-70.8	-61	0	0	0	111.2
4	I	42.3	Very low	40.1	Very low	173 Å²	173	141.3 Å²	141.3	89%	0.887	79%	0.79	S	S	*	*			trans	-98.7	82.7	164.4	-57.6	172	0	0	0	106
5	N	40.3	Very low	41.4	Very low	125 Å²	125	134.3 Å²	134.3	67%	0.668	76%	0.757	S	S	*	*			trans	-117.3	129.1	177	-103	-18.4	0	0	0	110.8
6	N	41.1	Very low	43.4	Very low	135 Å²	135	131.1 Å²	131.1	72%	0.722	74%	0.743	S	S	*	*			trans	69.3	74.4	151.9	-65.7	-15.9	0	0	0	119.2
7	T	38.5	Very low	45	Very low	142 Å²	142	133.9 Å²	133.9	87%	0.871	74%	0.741	S	S	*	*			trans	-112.4	53.2	146.2	8.1	0	0	0	0	110.7
8	T	35.5	Very low	46.7	Very low	125 Å²	125	131.2 Å²	131.2	77%	0.767	73%	0.733	S	S	*	*			trans	-100.9	65.7	159.1	-19.8	0	0	0	0	107.6	I10	T8-I10 VanDerWaalsContact C-N 3.29Å; T8-I10 PolarHBondContact O-N 3.47Å
9	Q	38.3	Very low	48.2	Very low	180 Å²	180	129 Å²	129	84%	0.841	72%	0.719	S	S	*	*			trans	-69.2	93.1	167.5	-84.7	-165	-15.2	0	0	108.8	L11	Q9-L11 PolarHBondContact O-N 3.2Å; Q9-L11 VanDerWaalsContact O-N 3.12Å
10	I	40.9	Very low	49.7	Very low	156 Å²	156	128.1 Å²	128.1	80%	0.8	70%	0.704	S	S	*	*			trans	20.8	81.4	136	-46.1	176	0	0	0	114	T8	T8-I10 VanDerWaalsContact C-N 3.29Å; T8-I10 PolarHBondContact O-N 3.47Å
11	L	33.5	Very low	51.4	Low	139 Å²	139	127.3 Å²	127.3	73%	0.728	70%	0.698	S	S	*	*			trans	-73.3	128.3	154.3	-165.4	74	0	0	0	106.6	Q9 S13	Q9-L11 PolarHBondContact O-N 3.2Å; Q9-L11 VanDerWaalsContact O-N 3.12Å; L11-S13 PolarHBondContact O-N 2.77Å
12	P	45	Very low	54	Low	95 Å²	95	118 Å²	118	62%	0.617	66%	0.66	S	S	*	*			trans	-57.7	129.3	176.8	23.8	-30.8	0	0	0	107.8	L14	P12-L14 PolarHBondContact O-N 2.78Å
13	S	46.5	Very low	56.5	Low	121 Å²	121	115 Å²	115	85%	0.846	63%	0.631	S	S	*	*			trans	-43.8	94.3	-176.6	54.3	0	0	0	0	111.4	L11 A15	L11-S13 PolarHBondContact O-N 2.77Å; S13-A15 PolarHBondContact O-N 2.93Å; S13-A15 VanDerWaalsContact O-N 3.07Å
14	L	51	Low	59.2	Low	92 Å²	92	109.8 Å²	109.8	48%	0.482	61%	0.605	S	S	.	*			trans	-68.7	111	177	-129.7	75.3	0	0	0	105.7	P12	P12-L14 PolarHBondContact O-N 2.78Å
15	A	59.3	Low	61.7	Low	37 Å²	37	107.1 Å²	107.1	31%	0.306	59%	0.592	S	S	.	*			trans	-45.1	137.8	170.6	0	0	0	0	0	109.8	S13 Y17 L19	S13-A15 PolarHBondContact O-N 2.93Å; S13-A15 VanDerWaalsContact O-N 3.07Å; A15-Y17 PolarHBondContact O-N 3.24Å; A15-L19 HydrophobicContact CB-CB 4.5Å; A15-L19 HydrophobicContact CB-CD2 3.86Å
16	P	73.1	Confident	64.2	Low	82 Å²	82	106 Å²	106	53%	0.532	59%	0.585	S	S	.	*			trans	-54.5	141.2	-174.9	21.5	-32	0	0	0	110.1	S18 L19 R20	P16-S18 PolarHBondContact O-N 3.47Å; P16-L19 HydrophobicContact CG-CB 4.2Å; P16-L19 WeakPolarHBondContact O-CA 3.39Å; P16-L19 WeakPolarHBondContact O-CB 3.25Å; P16-L19 PolarHBondContact O-N 3.3Å; P16-R20 PolarHBondContact O-N 3.39Å
17	Y	70.3	Confident	66.7	Low	179 Å²	179	99.8 Å²	99.8	70%	0.702	55%	0.552	S	S	*	*	H	α-helix	trans	-50.7	-32.2	-177.5	-72.4	-82.9	0	0	0	113.1	A15 L19 R20 I21	A15-Y17 PolarHBondContact O-N 3.24Å; Y17-L19 VanDerWaalsContact C-N 3.32Å; Y17-L19 PolarHBondContact O-N 2.75Å; Y17-R20 PolarHBondContact O-N 3.38Å; Y17-I21 PolarHBondContact O-N 3.16Å
18	S	75.1	Confident	69.4	Low	85 Å²	85	94.2 Å²	94.2	59%	0.594	52%	0.523	S	S	*	.	H	α-helix	trans	-58	-39.6	173	52.7	0	0	0	0	113.1	P16 I21 A22	P16-S18 PolarHBondContact O-N 3.47Å; S18-I21 PolarHBondContact O-N 3.41Å; S18-A22 WeakPolarHBondContact O-CB 3.44Å; S18-A22 PolarHBondContact O-N 3.27Å
19	L	75.3	Confident	72.3	Confident	90 Å²	90	93.9 Å²	93.9	47%	0.471	51%	0.511	S	S	.	.	H	α-helix	trans	-69.3	-38.7	178	-170.8	65.6	0	0	0	111.9	A15 P16 Y17 I21 L23	A15-L19 HydrophobicContact CB-CB 4.5Å; A15-L19 HydrophobicContact CB-CD2 3.86Å; P16-L19 HydrophobicContact CG-CB 4.2Å; P16-L19 WeakPolarHBondContact O-CA 3.39Å; P16-L19 WeakPolarHBondContact O-CB 3.25Å; P16-L19 PolarHBondContact O-N 3.3Å; Y17-L19 VanDerWaalsContact C-N 3.32Å; Y17-L19 PolarHBondContact O-N 2.75Å; L19-I21 PolarHBondContact O-N 2.91Å; L19-L23 VanDerWaalsContact O-CB 3.24Å; L19-L23 WeakPolarHBondContact O-CB 3.43Å; L19-L23 PolarHBondContact O-N 3.38Å
20	R	79.2	Confident	75	Confident	111 Å²	111	87.7 Å²	87.7	42%	0.419	48%	0.483	S	S	.	.	H	α-helix	trans	-65.1	-24.6	178.8	-69.4	-177.1	176.2	-109.7	-0	113.2	P16 Y17 P24	P16-R20 PolarHBondContact O-N 3.39Å; Y17-R20 PolarHBondContact O-N 3.38Å; R20-P24 WeakPolarHBondContact O-CD 3.38Å; R20-P24 WeakPolarHBondContact O-CG 3.18Å
21	I	85.8	Confident	77.7	Confident	112 Å²	112	81.7 Å²	81.7	57%	0.574	45%	0.452	S	S	*	.	H	α-helix	trans	-96.5	-42.5	176.6	-62.2	172.4	0	0	0	111.1	Y17 S18 L19 L23 P24 L25	Y17-I21 PolarHBondContact O-N 3.16Å; S18-I21 PolarHBondContact O-N 3.41Å; L19-I21 PolarHBondContact O-N 2.91Å; I21-L23 PolarHBondContact O-N 3.14Å; I21-P24 WeakPolarHBondContact O-CD 3.46Å; I21-L25 HydrophobicContact CG2-CD1 3.87Å; I21-L25 VanDerWaalsContact O-CG 3.31Å; I21-L25 WeakPolarHBondContact O-CG 3.38Å; I21-L25 PolarHBondContact O-N 3.32Å
22	A	89.7	Confident	80.7	Confident	53 Å²	53	80.8 Å²	80.8	44%	0.438	45%	0.447	S	S	.	.	H	α-helix	trans	-66.4	-39.2	-177.1	0	0	0	0	0	112.6	S18 L25 L26	S18-A22 WeakPolarHBondContact O-CB 3.44Å; S18-A22 PolarHBondContact O-N 3.27Å; A22-L25 PolarHBondContact O-N 2.93Å; A22-L26 VanDerWaalsContact O-CB 3.28Å; A22-L26 WeakPolarHBondContact O-CB 3.38Å; A22-L26 PolarHBondContact O-N 3.01Å
23	L	89.6	Confident	83.1	Confident	35 Å²	35	79.8 Å²	79.8	18%	0.183	44%	0.437	C	S	.	.	H	α-helix	trans	-64.6	-51.1	-177.4	179.5	73.1	0	0	0	112.7	L19 I21 L25 L26 V27 L78 E81 L82	L19-L23 VanDerWaalsContact O-CB 3.24Å; L19-L23 WeakPolarHBondContact O-CB 3.43Å; L19-L23 PolarHBondContact O-N 3.38Å; I21-L23 PolarHBondContact O-N 3.14Å; L23-L25 VanDerWaalsContact C-N 3.31Å; L23-L25 PolarHBondContact O-N 3.3Å; L23-L26 PolarHBondContact O-N 2.81Å; L23-V27 HydrophobicContact CD1-CG2 4.02Å; L23-V27 HydrophobicContact CG-CG2 4.4Å; L23-V27 WeakPolarHBondContact O-CB 3.41Å; L23-V27 WeakPolarHBondContact O-CG2 3.39Å; L23-V27 PolarHBondContact O-N 3.25Å; L23-L78 HydrophobicContact CD2-CD1 4.16Å; L23-L78 HydrophobicContact CG-CD1 4.01Å; L23-E81 HydrophobicContact CD2-CB 4.43Å; L23-E81 HydrophobicContact CD2-CG 3.67Å; L23-L82 HydrophobicContact CD2-CD2 4.43Å
24	P	93.3	Very high	85.5	Confident	38 Å²	38	74.1 Å²	74.1	25%	0.247	40%	0.397	C	S	.	.	H	α-helix	trans	-59.3	-39.2	175.1	-20	26.8	0	0	0	113.5	R20 I21 G28 L78 L82	R20-P24 WeakPolarHBondContact O-CD 3.38Å; R20-P24 WeakPolarHBondContact O-CG 3.18Å; I21-P24 WeakPolarHBondContact O-CD 3.46Å; P24-G28 WeakPolarHBondContact O-CA 3.49Å; P24-G28 PolarHBondContact O-N 2.9Å; P24-L78 HydrophobicContact CB-CD2 4.27Å; P24-L82 HydrophobicContact CB-CD1 4.44Å; P24-L82 HydrophobicContact CG-CD1 3.78Å; P24-L82 HydrophobicContact CG-CD2 3.8Å; P24-L82 HydrophobicContact CG-CG 4.4Å
25	L	93.8	Very high	87.8	Confident	118 Å²	118	71.8 Å²	71.8	62%	0.618	39%	0.386	S	S	*	.	H	α-helix	trans	-65	-45.6	178.1	-71.1	174.8	0	0	0	111.4	I21 A22 L23 F29	I21-L25 HydrophobicContact CG2-CD1 3.87Å; I21-L25 VanDerWaalsContact O-CG 3.31Å; I21-L25 WeakPolarHBondContact O-CG 3.38Å; I21-L25 PolarHBondContact O-N 3.32Å; A22-L25 PolarHBondContact O-N 2.93Å; L23-L25 VanDerWaalsContact C-N 3.31Å; L23-L25 PolarHBondContact O-N 3.3Å; L25-F29 VanDerWaalsContact O-CB 3.27Å; L25-F29 WeakPolarHBondContact O-CB 3.38Å; L25-F29 PolarHBondContact O-N 3.03Å
26	L	93.6	Very high	89.5	Confident	100 Å²	100	75.5 Å²	75.5	52%	0.524	40%	0.396	S	S	.	.	H	α-helix	trans	-63.1	-49	177.7	177.9	64.5	0	0	0	111.5	A22 L23 F29 M30	A22-L26 VanDerWaalsContact O-CB 3.28Å; A22-L26 WeakPolarHBondContact O-CB 3.38Å; A22-L26 PolarHBondContact O-N 3.01Å; L23-L26 PolarHBondContact O-N 2.81Å; L26-F29 PolarHBondContact O-N 3.07Å; L26-M30 WeakPolarHBondContact O-CG 3.5Å; L26-M30 PolarHBondContact O-N 3.46Å
27	V	93.8	Very high	90.6	Very high	5 Å²	5	72 Å²	72	3%	0.03	38%	0.375	C	S	.	.	H	α-helix	trans	-67.1	-42	-179.8	172.9	0	0	0	0	110.9	L23 F29 M30 I31 M74 L78 W385	L23-V27 HydrophobicContact CD1-CG2 4.02Å; L23-V27 HydrophobicContact CG-CG2 4.4Å; L23-V27 WeakPolarHBondContact O-CB 3.41Å; L23-V27 WeakPolarHBondContact O-CG2 3.39Å; L23-V27 PolarHBondContact O-N 3.25Å; V27-F29 VanDerWaalsContact C-N 3.34Å; V27-F29 PolarHBondContact O-N 3.35Å; V27-M30 WeakPolarHBondContact O-CB 3.5Å; V27-M30 PolarHBondContact O-N 2.89Å; V27-I31 HydrophobicContact CG1-CD1 4Å; V27-I31 HydrophobicContact CG1-CG1 4.44Å; V27-I31 WeakPolarHBondContact O-CG1 3.4Å; V27-I31 PolarHBondContact O-N 3.49Å; V27-M74 HydrophobicContact CG1-CE 4.14Å; V27-L78 HydrophobicContact CB-CD1 4.24Å; V27-L78 HydrophobicContact CB-CD2 4.16Å; V27-L78 HydrophobicContact CG1-CB 4.22Å; V27-L78 HydrophobicContact CG1-CD1 4.45Å; V27-L78 HydrophobicContact CG1-CD2 3.98Å; V27-L78 HydrophobicContact CG1-CG 4.45Å; V27-L78 HydrophobicContact CG2-CD1 4.22Å; V27-W385 HydrophobicContact CB-CH2 4.44Å; V27-W385 HydrophobicContact CB-CZ3 4.2Å; V27-W385 HydrophobicContact CG1-CH2 3.72Å; V27-W385 HydrophobicContact CG1-CZ3 3.51Å; V27-W385 HydrophobicContact CG2-CD2 4.48Å; V27-W385 HydrophobicContact CG2-CE3 3.89Å; V27-W385 HydrophobicContact CG2-CH2 3.83Å; V27-W385 HydrophobicContact CG2-CZ2 4.39Å; V27-W385 HydrophobicContact CG2-CZ3 3.55Å
28	G	95.8	Very high	91.9	Very high	26 Å²	26	63.5 Å²	63.5	27%	0.268	34%	0.342	S	S	.	.	H	α-helix	trans	-60.3	-43.4	174.8	0	0	0	0	0	112.1	P24 I31 L32	P24-G28 WeakPolarHBondContact O-CA 3.49Å; P24-G28 PolarHBondContact O-N 2.9Å; G28-I31 PolarHBondContact O-N 3.35Å; G28-L32 WeakPolarHBondContact O-CG 3.23Å; G28-L32 PolarHBondContact O-N 2.95Å
29	F	95.6	Very high	92.9	Very high	117 Å²	117	62.3 Å²	62.3	51%	0.513	33%	0.33	S	S	.	.	H	α-helix	trans	-62	-42.6	173.3	178.8	-107.1	0	0	0	112.2	L25 L26 V27 L32 L33	L25-F29 VanDerWaalsContact O-CB 3.27Å; L25-F29 WeakPolarHBondContact O-CB 3.38Å; L25-F29 PolarHBondContact O-N 3.03Å; L26-F29 PolarHBondContact O-N 3.07Å; V27-F29 VanDerWaalsContact C-N 3.34Å; V27-F29 PolarHBondContact O-N 3.35Å; F29-L32 PolarHBondContact O-N 3.34Å; F29-L33 HydrophobicContact CD1-CD1 3.91Å; F29-L33 HydrophobicContact CD1-CG 4.4Å; F29-L33 HydrophobicContact CE1-CD1 3.32Å; F29-L33 HydrophobicContact CE1-CG 4.01Å; F29-L33 HydrophobicContact CE2-CD1 4.42Å; F29-L33 HydrophobicContact CE2-CD2 4.4Å; F29-L33 HydrophobicContact CE2-CG 4.27Å; F29-L33 HydrophobicContact CZ-CD1 3.62Å; F29-L33 HydrophobicContact CZ-CD2 4.11Å; F29-L33 HydrophobicContact CZ-CG 3.93Å; F29-L33 WeakPolarHBondContact O-CG 3.45Å; F29-L33 PolarHBondContact O-N 3.44Å
30	M	95.3	Very high	93.8	Very high	50 Å²	50	58.6 Å²	58.6	25%	0.246	31%	0.311	C	S	.	.	H	α-helix	trans	-59.9	-46.7	174.2	-77.2	-72.5	-178.3	0	0	112	L26 V27 L32 L33 I34 M74 A392	L26-M30 WeakPolarHBondContact O-CG 3.5Å; L26-M30 PolarHBondContact O-N 3.46Å; V27-M30 WeakPolarHBondContact O-CB 3.5Å; V27-M30 PolarHBondContact O-N 2.89Å; M30-L32 VanDerWaalsContact C-N 3.31Å; M30-L32 PolarHBondContact O-N 3.39Å; M30-L33 PolarHBondContact O-N 2.76Å; M30-I34 VanDerWaalsContact O-CG1 3.22Å; M30-I34 WeakPolarHBondContact O-CG1 3.26Å; M30-I34 PolarHBondContact O-N 3.3Å; M30-M74 HydrophobicContact CB-CE 4.15Å; M30-A392 HydrophobicContact SD-CB 4.45Å
31	I	97.1	Very high	94.6	Very high	30 Å²	30	53.3 Å²	53.3	15%	0.154	29%	0.291	C	S	.	.	H	α-helix	trans	-56.8	-47	176.7	-70.3	166.9	0	0	0	110.4	V27 G28 L33 I34 V35 A70 M74 P75	V27-I31 HydrophobicContact CG1-CD1 4Å; V27-I31 HydrophobicContact CG1-CG1 4.44Å; V27-I31 WeakPolarHBondContact O-CG1 3.4Å; V27-I31 PolarHBondContact O-N 3.49Å; G28-I31 PolarHBondContact O-N 3.35Å; I31-L33 PolarHBondContact O-N 3.1Å; I31-I34 PolarHBondContact O-N 3.43Å; I31-V35 HydrophobicContact CG2-CG2 4.32Å; I31-V35 WeakPolarHBondContact O-CB 3.38Å; I31-V35 WeakPolarHBondContact O-CG2 3.42Å; I31-V35 PolarHBondContact O-N 3.23Å; I31-A70 HydrophobicContact CG2-CB 4.34Å; I31-M74 HydrophobicContact CD1-CB 3.91Å; I31-M74 HydrophobicContact CG1-CB 3.92Å; I31-M74 HydrophobicContact CG1-CE 3.91Å; I31-M74 HydrophobicContact CG1-SD 3.96Å; I31-P75 HydrophobicContact CD1-CG 4.16Å
32	L	96.8	Very high	95	Very high	120 Å²	120	49.5 Å²	49.5	63%	0.628	27%	0.273	S	S	*	.	H	α-helix	trans	-59.9	-44.9	177.9	-70.9	174.2	0	0	0	112	G28 F29 M30 F36	G28-L32 WeakPolarHBondContact O-CG 3.23Å; G28-L32 PolarHBondContact O-N 2.95Å; F29-L32 PolarHBondContact O-N 3.34Å; M30-L32 VanDerWaalsContact C-N 3.31Å; M30-L32 PolarHBondContact O-N 3.39Å; L32-F36 WeakPolarHBondContact O-CB 3.35Å; L32-F36 PolarHBondContact O-N 2.99Å
33	L	95.9	Very high	95.2	Very high	75 Å²	75	50.2 Å²	50.2	39%	0.393	27%	0.269	S	S	.	.	H	α-helix	trans	-62.3	-44.4	176.8	-73.9	-178.8	0	0	0	112.3	F29 M30 I31 G37	F29-L33 HydrophobicContact CD1-CD1 3.91Å; F29-L33 HydrophobicContact CD1-CG 4.4Å; F29-L33 HydrophobicContact CE1-CD1 3.32Å; F29-L33 HydrophobicContact CE1-CG 4.01Å; F29-L33 HydrophobicContact CE2-CD1 4.42Å; F29-L33 HydrophobicContact CE2-CD2 4.4Å; F29-L33 HydrophobicContact CE2-CG 4.27Å; F29-L33 HydrophobicContact CZ-CD1 3.62Å; F29-L33 HydrophobicContact CZ-CD2 4.11Å; F29-L33 HydrophobicContact CZ-CG 3.93Å; F29-L33 WeakPolarHBondContact O-CG 3.45Å; F29-L33 PolarHBondContact O-N 3.44Å; M30-L33 PolarHBondContact O-N 2.76Å; I31-L33 PolarHBondContact O-N 3.1Å; L33-G37 PolarHBondContact O-N 2.98Å
34	I	96.9	Very high	95.4	Very high	1 Å²	1	48.5 Å²	48.5	1%	0.005	26%	0.26	C	S	.	.	H	α-helix	trans	-63.1	-51.5	-179.7	-65.6	162.7	0	0	0	109.9	M30 I31 N38 D66 A70 M74 A392	M30-I34 VanDerWaalsContact O-CG1 3.22Å; M30-I34 WeakPolarHBondContact O-CG1 3.26Å; M30-I34 PolarHBondContact O-N 3.3Å; I31-I34 PolarHBondContact O-N 3.43Å; I34-N38 VanDerWaalsContact O-CB 3.28Å; I34-N38 WeakPolarHBondContact O-CB 3.44Å; I34-N38 PolarHBondContact O-N 3.01Å; I34-N38 PolarHBondContact O-ND2 2.92Å; I34-D66 HydrophobicContact CG2-CB 4.32Å; I34-D66 WeakPolarHBondContact CG2-O 3.18Å; I34-A70 HydrophobicContact CB-CB 3.91Å; I34-A70 HydrophobicContact CD1-CB 4.29Å; I34-A70 HydrophobicContact CG2-CB 3.63Å; I34-M74 HydrophobicContact CD1-CE 4.14Å; I34-M74 HydrophobicContact CD1-SD 3.54Å; I34-M74 VanDerWaalsContact CD1-SD 3.54Å; I34-A392 HydrophobicContact CD1-CB 4.46Å; I34-A392 HydrophobicContact CG1-CB 3.66Å
35	V	97.8	Very high	95.4	Very high	44 Å²	44	47 Å²	47	27%	0.267	25%	0.25	S	C	.	.	H	α-helix	trans	-62.7	-51.7	-179	173.5	0	0	0	0	110.1	I31 G37 V39 A70 T71	I31-V35 HydrophobicContact CG2-CG2 4.32Å; I31-V35 WeakPolarHBondContact O-CB 3.38Å; I31-V35 WeakPolarHBondContact O-CG2 3.42Å; I31-V35 PolarHBondContact O-N 3.23Å; V35-G37 PolarHBondContact O-N 3.41Å; V35-V39 HydrophobicContact CG1-CG2 4.21Å; V35-V39 VanDerWaalsContact O-CB 3.23Å; V35-V39 WeakPolarHBondContact O-CB 3.48Å; V35-V39 WeakPolarHBondContact O-CG2 3.3Å; V35-V39 PolarHBondContact O-N 3.29Å; V35-A70 HydrophobicContact CG2-CB 3.96Å; V35-T71 HydrophobicContact CG2-CG2 4.02Å
36	F	96.3	Very high	95.3	Very high	114 Å²	114	46.7 Å²	46.7	50%	0.5	24%	0.244	S	C	.	.	H	α-helix	trans	-59.6	-50.4	-179.1	176.7	-101.4	0	0	0	112.2	L32 V39 L40 L413	L32-F36 WeakPolarHBondContact O-CB 3.35Å; L32-F36 PolarHBondContact O-N 2.99Å; F36-V39 PolarHBondContact O-N 3.43Å; F36-L40 HydrophobicContact CD1-CD1 3.99Å; F36-L40 HydrophobicContact CE1-CD1 3.45Å; F36-L40 VanDerWaalsContact CE1-CD1 3.45Å; F36-L40 HydrophobicContact CE1-CG 4.41Å; F36-L40 HydrophobicContact CE2-CD1 4.27Å; F36-L40 HydrophobicContact CZ-CD1 3.64Å; F36-L40 HydrophobicContact CZ-CG 4.36Å; F36-L40 WeakPolarHBondContact O-CG 3.25Å; F36-L40 PolarHBondContact O-N 2.9Å; F36-L413 HydrophobicContact CE2-CD2 4.34Å; F36-L413 HydrophobicContact CZ-CD2 3.71Å
37	G	95.6	Very high	95.1	Very high	10 Å²	10	45.8 Å²	45.8	10%	0.103	24%	0.243	C	C	.	.	H	α-helix	trans	-62.8	-46	-177.6	0	0	0	0	0	112.4	L33 V35 L40 V41	L33-G37 PolarHBondContact O-N 2.98Å; V35-G37 PolarHBondContact O-N 3.41Å; G37-L40 WeakPolarHBondContact O-CB 3.48Å; G37-L40 PolarHBondContact O-N 3.42Å; G37-V41 WeakPolarHBondContact O-CG2 3.28Å; G37-V41 PolarHBondContact O-N 3.31Å; G37-V41 VanDerWaalsContact O-N 3.09Å
38	N	96.8	Very high	94.9	Very high	0 Å²	0	46.8 Å²	46.8	0%	0	25%	0.25	C	C	.	.	H	α-helix	trans	-74.4	-33.4	-178.7	-74.4	-65.8	0	0	0	112.5	I34 L40 V41 V42 A63 I67 S391 P395	I34-N38 VanDerWaalsContact O-CB 3.28Å; I34-N38 WeakPolarHBondContact O-CB 3.44Å; I34-N38 PolarHBondContact O-N 3.01Å; I34-N38 PolarHBondContact O-ND2 2.92Å; N38-L40 VanDerWaalsContact C-N 3.32Å; N38-L40 PolarHBondContact O-N 3.36Å; N38-V41 WeakPolarHBondContact O-CB 3.35Å; N38-V41 PolarHBondContact O-N 2.85Å; N38-V41 VanDerWaalsContact O-N 3.17Å; N38-V42 WeakPolarHBondContact O-CG2 3.44Å; N38-V42 PolarHBondContact O-N 2.92Å; N38-A63 HydrophobicContact CB-CB 3.94Å; N38-I67 HydrophobicContact CB-CD1 3.93Å; N38-I67 HydrophobicContact CB-CG1 3.65Å; N38-S391 PolarHBondContact ND2-O 3.04Å; N38-P395 WeakPolarHBondContact OD1-CG 3.49Å
39	V	96.7	Very high	94.5	Very high	59 Å²	59	56.2 Å²	56.2	36%	0.358	28%	0.277	S	S	.	.	H	α-helix	trans	-61.2	-41.5	169.8	168	0	0	0	0	110.8	V35 F36 V41 V42 I43 I67	V35-V39 HydrophobicContact CG1-CG2 4.21Å; V35-V39 VanDerWaalsContact O-CB 3.23Å; V35-V39 WeakPolarHBondContact O-CB 3.48Å; V35-V39 WeakPolarHBondContact O-CG2 3.3Å; V35-V39 PolarHBondContact O-N 3.29Å; F36-V39 PolarHBondContact O-N 3.43Å; V39-V41 VanDerWaalsContact C-N 3.33Å; V39-V41 PolarHBondContact O-N 2.91Å; V39-V42 PolarHBondContact O-N 3Å; V39-I43 HydrophobicContact CG1-CD1 3.67Å; V39-I43 HydrophobicContact CG1-CG1 4.26Å; V39-I43 VanDerWaalsContact O-CG1 3.31Å; V39-I43 WeakPolarHBondContact O-CG1 3.4Å; V39-I43 PolarHBondContact O-N 3.34Å; V39-I67 HydrophobicContact CG2-CD1 3.82Å
40	L	94.9	Very high	93.9	Very high	13 Å²	13	53.8 Å²	53.8	7%	0.068	28%	0.279	C	S	.	.	H	α-helix	trans	-61.1	-39.9	173.8	-74.3	177.7	0	0	0	112.5	F36 G37 N38 I43 A44 F409 I412 L413	F36-L40 HydrophobicContact CD1-CD1 3.99Å; F36-L40 HydrophobicContact CE1-CD1 3.45Å; F36-L40 VanDerWaalsContact CE1-CD1 3.45Å; F36-L40 HydrophobicContact CE1-CG 4.41Å; F36-L40 HydrophobicContact CE2-CD1 4.27Å; F36-L40 HydrophobicContact CZ-CD1 3.64Å; F36-L40 HydrophobicContact CZ-CG 4.36Å; F36-L40 WeakPolarHBondContact O-CG 3.25Å; F36-L40 PolarHBondContact O-N 2.9Å; G37-L40 WeakPolarHBondContact O-CB 3.48Å; G37-L40 PolarHBondContact O-N 3.42Å; N38-L40 VanDerWaalsContact C-N 3.32Å; N38-L40 PolarHBondContact O-N 3.36Å; L40-I43 PolarHBondContact O-N 3.23Å; L40-A44 WeakPolarHBondContact O-CB 3.3Å; L40-A44 PolarHBondContact O-N 3.46Å; L40-F409 HydrophobicContact CB-CD1 4.31Å; L40-F409 HydrophobicContact CB-CE1 3.91Å; L40-F409 HydrophobicContact CB-CE2 4.16Å; L40-F409 HydrophobicContact CB-CZ 3.83Å; L40-F409 HydrophobicContact CD1-CD2 4.4Å; L40-F409 WeakPolarHBondContact O-CE1 3.32Å; L40-I412 HydrophobicContact CD2-CB 4.49Å; L40-I412 HydrophobicContact CD2-CG2 3.71Å; L40-L413 HydrophobicContact CD1-CD1 4.31Å; L40-L413 HydrophobicContact CD1-CD2 4.27Å; L40-L413 HydrophobicContact CD2-CD2 4.21Å
41	V	95	Very high	93.5	Very high	0 Å²	0	51.6 Å²	51.6	0%	0	27%	0.268	C	S	.	.	H	α-helix	trans	-57.8	-50.8	174	173.8	0	0	0	0	110.2	G37 N38 V39 A44 V45 A63 P395 Y398 F405 F409	G37-V41 WeakPolarHBondContact O-CG2 3.28Å; G37-V41 PolarHBondContact O-N 3.31Å; G37-V41 VanDerWaalsContact O-N 3.09Å; N38-V41 WeakPolarHBondContact O-CB 3.35Å; N38-V41 PolarHBondContact O-N 2.85Å; N38-V41 VanDerWaalsContact O-N 3.17Å; V39-V41 VanDerWaalsContact C-N 3.33Å; V39-V41 PolarHBondContact O-N 2.91Å; V41-A44 PolarHBondContact O-N 2.86Å; V41-V45 WeakPolarHBondContact O-CG2 3.35Å; V41-V45 PolarHBondContact O-N 3.18Å; V41-A63 HydrophobicContact CB-CB 4.26Å; V41-A63 HydrophobicContact CG1-CB 4.12Å; V41-P395 HydrophobicContact CG2-CB 4.04Å; V41-P395 HydrophobicContact CG2-CG 4.11Å; V41-Y398 HydrophobicContact CG1-CD2 4.38Å; V41-Y398 HydrophobicContact CG1-CE2 4.44Å; V41-Y398 HydrophobicContact CG2-CD2 3.82Å; V41-Y398 HydrophobicContact CG2-CE2 4.29Å; V41-F405 HydrophobicContact CG1-CE1 4.16Å; V41-F405 HydrophobicContact CG1-CZ 4.48Å; V41-F409 HydrophobicContact CG2-CZ 3.79Å
42	V	95.9	Very high	92.9	Very high	32 Å²	32	57.6 Å²	57.6	19%	0.194	29%	0.288	C	S	.	.	H	α-helix	trans	-57.8	-52.6	179.3	174.7	0	0	0	0	110.7	N38 V39 A44 V45 F46 V60 A63	N38-V42 WeakPolarHBondContact O-CG2 3.44Å; N38-V42 PolarHBondContact O-N 2.92Å; V39-V42 PolarHBondContact O-N 3Å; V42-A44 VanDerWaalsContact C-N 3.33Å; V42-A44 PolarHBondContact O-N 2.93Å; V42-V45 PolarHBondContact O-N 3.26Å; V42-F46 HydrophobicContact CG1-CD2 3.85Å; V42-F46 HydrophobicContact CG1-CE2 3.83Å; V42-F46 WeakPolarHBondContact O-CD2 3.34Å; V42-F46 PolarHBondContact O-N 3.45Å; V42-V60 HydrophobicContact CG1-CG1 4.41Å; V42-V60 HydrophobicContact CG2-CG1 4.3Å; V42-A63 HydrophobicContact CG2-CB 3.92Å
43	I	93.9	Very high	92.4	Very high	67 Å²	67	53.3 Å²	53.3	34%	0.344	27%	0.27	S	S	.	.	H	α-helix	trans	-59.5	-44.6	179.4	-66.1	171	0	0	0	110.7	V39 L40 V45 F46 T47 I412	V39-I43 HydrophobicContact CG1-CD1 3.67Å; V39-I43 HydrophobicContact CG1-CG1 4.26Å; V39-I43 VanDerWaalsContact O-CG1 3.31Å; V39-I43 WeakPolarHBondContact O-CG1 3.4Å; V39-I43 PolarHBondContact O-N 3.34Å; L40-I43 PolarHBondContact O-N 3.23Å; I43-V45 PolarHBondContact O-N 3.13Å; I43-F46 PolarHBondContact O-N 3.34Å; I43-T47 HydrophobicContact CG2-CG2 3.79Å; I43-T47 VanDerWaalsContact O-CB 3.29Å; I43-T47 WeakPolarHBondContact O-CB 3.44Å; I43-T47 VanDerWaalsContact O-CG2 3.24Å; I43-T47 WeakPolarHBondContact O-CG2 3.41Å; I43-T47 PolarHBondContact O-N 3.35Å; I43-T47 PolarHBondContact O-OG1 3.42Å; I43-I412 HydrophobicContact CB-CD1 4.35Å; I43-I412 HydrophobicContact CG2-CD1 3.74Å; I43-I412 HydrophobicContact CG2-CG1 4.26Å
44	A	92.8	Very high	92.1	Very high	0 Å²	0	51.2 Å²	51.2	0%	0	26%	0.261	C	S	.	.	H	α-helix	trans	-61.9	-41.2	-178.4	0	0	0	0	0	112.6	L40 V41 V42 S48 L51 F405 F409 I412	L40-A44 WeakPolarHBondContact O-CB 3.3Å; L40-A44 PolarHBondContact O-N 3.46Å; V41-A44 PolarHBondContact O-N 2.86Å; V42-A44 VanDerWaalsContact C-N 3.33Å; V42-A44 PolarHBondContact O-N 2.93Å; A44-S48 WeakPolarHBondContact O-CB 3.01Å; A44-S48 PolarHBondContact O-N 3.2Å; A44-L51 HydrophobicContact CB-CD1 4.11Å; A44-F405 HydrophobicContact CB-CD1 4.18Å; A44-F405 HydrophobicContact CB-CE1 4.27Å; A44-F409 HydrophobicContact CB-CD1 3.83Å; A44-F409 HydrophobicContact CB-CE1 3.6Å; A44-I412 HydrophobicContact CB-CD1 4Å
45	V	93.3	Very high	91.6	Very high	5 Å²	5	53.4 Å²	53.4	3%	0.03	27%	0.271	C	S	.	.	H	α-helix	trans	-65.3	-42.3	178.4	174.2	0	0	0	0	111.4	V41 V42 I43 N56 V60 F405	V41-V45 WeakPolarHBondContact O-CG2 3.35Å; V41-V45 PolarHBondContact O-N 3.18Å; V42-V45 PolarHBondContact O-N 3.26Å; I43-V45 PolarHBondContact O-N 3.13Å; V45-N56 HydrophobicContact CG1-CB 4.06Å; V45-N56 HydrophobicContact CG2-CB 4.37Å; V45-V60 HydrophobicContact CB-CG2 3.69Å; V45-V60 HydrophobicContact CG1-CG2 3.57Å; V45-V60 HydrophobicContact CG2-CG2 3.97Å; V45-F405 HydrophobicContact CG2-CE1 3.89Å; V45-F405 HydrophobicContact CG2-CZ 3.84Å
46	F	92.1	Very high	91.4	Very high	112 Å²	112	52.3 Å²	52.3	49%	0.491	26%	0.264	S	S	.	.	H	α-helix	trans	-76.5	-34.7	-179.2	-73.2	-64.1	0	0	0	113.5	V42 I43 R52 V60	V42-F46 HydrophobicContact CG1-CD2 3.85Å; V42-F46 HydrophobicContact CG1-CE2 3.83Å; V42-F46 WeakPolarHBondContact O-CD2 3.34Å; V42-F46 PolarHBondContact O-N 3.45Å; I43-F46 PolarHBondContact O-N 3.34Å; F46-R52 PolarHBondContact O-NE 2.91Å; F46-R52 PolarHBondContact O-NH2 3.12Å; F46-V60 HydrophobicContact CE2-CG1 3.8Å; F46-V60 HydrophobicContact CE2-CG2 4.26Å; F46-V60 HydrophobicContact CZ-CG1 4.1Å
47	T	89.6	Confident	91.2	Very high	82 Å²	82	48.6 Å²	48.6	50%	0.503	25%	0.249	S	C	.	.	H	α-helix	trans	-84.7	-34.2	-176.8	58.1	0	0	0	0	113.4	I43	I43-T47 HydrophobicContact CG2-CG2 3.79Å; I43-T47 VanDerWaalsContact O-CB 3.29Å; I43-T47 WeakPolarHBondContact O-CB 3.44Å; I43-T47 VanDerWaalsContact O-CG2 3.24Å; I43-T47 WeakPolarHBondContact O-CG2 3.41Å; I43-T47 PolarHBondContact O-N 3.35Å; I43-T47 PolarHBondContact O-OG1 3.42Å
48	S	89.3	Confident	91.2	Very high	25 Å²	25	48.3 Å²	48.3	18%	0.175	25%	0.245	C	C	.	.			trans	-91	117.2	-172.9	-171.3	0	0	0	0	112.3	A44 A50 L51 R52 S408	A44-S48 WeakPolarHBondContact O-CB 3.01Å; A44-S48 PolarHBondContact O-N 3.2Å; S48-A50 PolarHBondContact O-N 3.41Å; S48-A50 VanDerWaalsContact O-N 3.15Å; S48-L51 PolarHBondContact O-N 2.99Å; S48-R52 WeakPolarHBondContact O-CG 3.49Å; S48-R52 PolarHBondContact O-N 3.22Å; S48-S408 WeakPolarHBondContact CB-OG 3.18Å; S48-S408 PolarHBondContact OG-OG 3Å; S48-S408 VanDerWaalsContact OG-OG 3.07Å
49	R	86.2	Confident	91	Very high	225 Å²	225	49.3 Å²	49.3	85%	0.849	25%	0.25	S	S	*	.	G	3₁₀ helix	trans	-58	-30.3	177.2	-153.3	-178.3	-160.1	-176.6	6.5	112.8	L51	R49-L51 VanDerWaalsContact C-N 3.27Å; R49-L51 PolarHBondContact O-N 2.87Å
50	A	84.4	Confident	90.9	Very high	66 Å²	66	47.2 Å²	47.2	55%	0.545	24%	0.238	S	C	.	.	G	3₁₀ helix	trans	-69.2	-24.2	176.8	0	0	0	0	0	113.1	S48	S48-A50 PolarHBondContact O-N 3.41Å; S48-A50 VanDerWaalsContact O-N 3.15Å
51	L	85.8	Confident	91	Very high	3 Å²	3	47.1 Å²	47.1	2%	0.016	24%	0.239	C	C	.	.	G	3₁₀ helix	trans	-104.1	3	-178	-62.7	172.7	0	0	0	113.2	A44 S48 R49 A53 N56 D404 F405	A44-L51 HydrophobicContact CB-CD1 4.11Å; S48-L51 PolarHBondContact O-N 2.99Å; R49-L51 VanDerWaalsContact C-N 3.27Å; R49-L51 PolarHBondContact O-N 2.87Å; L51-A53 PolarHBondContact O-N 3.18Å; L51-N56 WeakPolarHBondContact CA-ND2 3.49Å; L51-N56 WeakPolarHBondContact O-CB 3.42Å; L51-N56 PolarHBondContact O-ND2 2.85Å; L51-D404 HydrophobicContact CD2-CB 3.83Å; L51-D404 HydrophobicContact CG-CB 4.37Å; L51-F405 HydrophobicContact CD1-CD1 3.78Å; L51-F405 HydrophobicContact CD1-CE1 3.85Å; L51-F405 HydrophobicContact CD1-CG 4.17Å; L51-F405 HydrophobicContact CD1-CZ 4.31Å; L51-F405 HydrophobicContact CD2-CD2 4.14Å; L51-F405 HydrophobicContact CD2-CE2 4.05Å; L51-F405 HydrophobicContact CD2-CG 4.46Å; L51-F405 HydrophobicContact CD2-CZ 4.29Å
52	R	84.6	Confident	91.1	Very high	156 Å²	156	47.2 Å²	47.2	59%	0.589	24%	0.239	S	C	*	.			trans	-77.2	17.3	178.8	-74.3	-179.2	-175.5	-179.6	-0.2	114.8	F46 S48	F46-R52 PolarHBondContact O-NE 2.91Å; F46-R52 PolarHBondContact O-NH2 3.12Å; S48-R52 WeakPolarHBondContact O-CG 3.49Å; S48-R52 PolarHBondContact O-N 3.22Å
53	A	87.8	Confident	91.1	Very high	30 Å²	30	45.7 Å²	45.7	25%	0.248	23%	0.23	C	C	.	.			trans	-70.2	143	177.6	0	0	0	0	0	110.5	L51 Q55 N56	L51-A53 PolarHBondContact O-N 3.18Å; A53-Q55 VanDerWaalsContact CB-CD 3.47Å; A53-Q55 PolarHBondContact O-N 2.89Å; A53-Q55 VanDerWaalsContact O-N 3.13Å; A53-N56 WeakPolarHBondContact O-CB 3.41Å; A53-N56 PolarHBondContact O-N 3.38Å
54	P	87.6	Confident	91.3	Very high	31 Å²	31	44.8 Å²	44.8	20%	0.201	23%	0.229	C	C	.	.	T	Hydrogen-bonded Turn	trans	-55.4	-36.4	-173.1	-26.8	34.3	0	0	0	114.2	N56 L57 P134 I137	P54-N56 PolarHBondContact O-N 3.28Å; P54-L57 WeakPolarHBondContact O-CB 3.24Å; P54-L57 WeakPolarHBondContact O-CG 3.24Å; P54-L57 PolarHBondContact O-N 3.46Å; P54-L57 VanDerWaalsContact O-N 3.16Å; P54-P134 HydrophobicContact CB-CG 4.31Å; P54-P134 HydrophobicContact CG-CG 4.08Å; P54-I137 HydrophobicContact CB-CG1 4.12Å
55	Q	88.1	Confident	91.5	Very high	47 Å²	47	44.8 Å²	44.8	22%	0.22	23%	0.229	C	C	.	.	T	Hydrogen-bonded Turn	trans	-64.6	-23.4	179.1	68.8	-81.6	6.9	0	0	113.8	A53 L57 F58 R132	A53-Q55 VanDerWaalsContact CB-CD 3.47Å; A53-Q55 PolarHBondContact O-N 2.89Å; A53-Q55 VanDerWaalsContact O-N 3.13Å; Q55-L57 PolarHBondContact O-N 2.74Å; Q55-F58 WeakPolarHBondContact O-CB 3.35Å; Q55-F58 WeakPolarHBondContact O-CD2 3.25Å; Q55-F58 PolarHBondContact O-N 3.08Å; Q55-R132 VanDerWaalsContact CD-NH1 3.26Å
56	N	91.8	Very high	91.6	Very high	21 Å²	21	44.5 Å²	44.5	11%	0.112	23%	0.228	C	C	.	.	H	α-helix	trans	-73.9	-9.8	179.2	-65.1	-11.2	0	0	0	111.9	V45 L51 A53 P54 F58 L59 V60	V45-N56 HydrophobicContact CG1-CB 4.06Å; V45-N56 HydrophobicContact CG2-CB 4.37Å; L51-N56 WeakPolarHBondContact CA-ND2 3.49Å; L51-N56 WeakPolarHBondContact O-CB 3.42Å; L51-N56 PolarHBondContact O-ND2 2.85Å; A53-N56 WeakPolarHBondContact O-CB 3.41Å; A53-N56 PolarHBondContact O-N 3.38Å; P54-N56 PolarHBondContact O-N 3.28Å; N56-F58 PolarHBondContact O-N 2.99Å; N56-L59 WeakPolarHBondContact O-CB 3.29Å; N56-L59 PolarHBondContact O-N 2.98Å; N56-L59 VanDerWaalsContact O-N 3.17Å; N56-V60 PolarHBondContact O-N 3.19Å
57	L	93.6	Very high	91.9	Very high	37 Å²	37	40.8 Å²	40.8	19%	0.194	21%	0.212	C	C	.	.	H	α-helix	trans	-64.4	-28.5	169.3	-68.6	173.4	0	0	0	112.3	P54 Q55 L59 V60 S61 I137 K138 I141	P54-L57 WeakPolarHBondContact O-CB 3.24Å; P54-L57 WeakPolarHBondContact O-CG 3.24Å; P54-L57 PolarHBondContact O-N 3.46Å; P54-L57 VanDerWaalsContact O-N 3.16Å; Q55-L57 PolarHBondContact O-N 2.74Å; L57-L59 VanDerWaalsContact C-N 3.28Å; L57-L59 PolarHBondContact O-N 3.34Å; L57-V60 PolarHBondContact O-N 3.47Å; L57-S61 PolarHBondContact O-N 2.92Å; L57-I137 HydrophobicContact CB-CG2 3.97Å; L57-I137 HydrophobicContact CD1-CG2 4.45Å; L57-K138 HydrophobicContact CD1-CG 4.32Å; L57-I141 HydrophobicContact CB-CD1 3.96Å
58	F	94.3	Very high	92.3	Very high	3 Å²	3	39.6 Å²	39.6	1%	0.013	20%	0.203	C	C	.	.	H	α-helix	trans	-61.8	-39.3	172	-70.1	-59.3	0	0	0	111.7	Q55 N56 V60 S61 L62 A113 I114 D117 I137 I140 I141	Q55-F58 WeakPolarHBondContact O-CB 3.35Å; Q55-F58 WeakPolarHBondContact O-CD2 3.25Å; Q55-F58 PolarHBondContact O-N 3.08Å; N56-F58 PolarHBondContact O-N 2.99Å; F58-V60 VanDerWaalsContact C-N 3.32Å; F58-S61 PolarHBondContact O-N 2.84Å; F58-L62 WeakPolarHBondContact O-CB 3.47Å; F58-L62 PolarHBondContact O-N 2.98Å; F58-A113 HydrophobicContact CE1-CB 4.15Å; F58-I114 HydrophobicContact CB-CD1 3.95Å; F58-I114 HydrophobicContact CB-CG1 3.56Å; F58-I114 HydrophobicContact CD2-CG1 4.3Å; F58-I114 HydrophobicContact CG-CG1 4.02Å; F58-D117 HydrophobicContact CE2-CB 4.11Å; F58-I137 HydrophobicContact CD1-CG2 4.35Å; F58-I137 HydrophobicContact CD2-CG2 4.19Å; F58-I137 HydrophobicContact CE1-CG2 4.07Å; F58-I137 HydrophobicContact CE2-CD1 3.67Å; F58-I137 HydrophobicContact CE2-CG2 3.93Å; F58-I137 HydrophobicContact CG-CG2 4.39Å; F58-I137 HydrophobicContact CZ-CD1 3.84Å; F58-I137 HydrophobicContact CZ-CG2 3.86Å; F58-I140 HydrophobicContact CE1-CB 4.1Å; F58-I140 HydrophobicContact CE1-CG2 3.68Å; F58-I140 HydrophobicContact CZ-CB 4.18Å; F58-I140 HydrophobicContact CZ-CD1 4.25Å; F58-I140 HydrophobicContact CZ-CG2 3.89Å; F58-I141 HydrophobicContact CD1-CD1 4.24Å; F58-I141 HydrophobicContact CD1-CG1 3.71Å; F58-I141 HydrophobicContact CE1-CG1 3.89Å
59	L	93.1	Very high	92.6	Very high	21 Å²	21	38.6 Å²	38.6	11%	0.11	20%	0.196	C	C	.	.	H	α-helix	trans	-67.5	-35.2	178.2	-56.2	177.7	0	0	0	111.7	N56 L57 A63 I114 Y398 F405	N56-L59 WeakPolarHBondContact O-CB 3.29Å; N56-L59 PolarHBondContact O-N 2.98Å; N56-L59 VanDerWaalsContact O-N 3.17Å; L57-L59 VanDerWaalsContact C-N 3.28Å; L57-L59 PolarHBondContact O-N 3.34Å; L59-A63 VanDerWaalsContact O-CB 3.24Å; L59-A63 WeakPolarHBondContact O-CB 3.2Å; L59-A63 PolarHBondContact O-N 3.39Å; L59-I114 HydrophobicContact CD2-CD1 4.04Å; L59-Y398 HydrophobicContact CD2-CE1 3.85Å; L59-Y398 HydrophobicContact CD2-CE2 4.49Å; L59-F405 HydrophobicContact CD1-CE2 3.67Å; L59-F405 HydrophobicContact CD1-CZ 3.69Å
60	V	95.9	Very high	93.2	Very high	15 Å²	15	27.9 Å²	27.9	9%	0.091	16%	0.155	C	C	.	.	H	α-helix	trans	-65.3	-48	174.3	175	0	0	0	0	110.5	V42 V45 F46 N56 L57 F58 L62 A63 S64	V42-V60 HydrophobicContact CG1-CG1 4.41Å; V42-V60 HydrophobicContact CG2-CG1 4.3Å; V45-V60 HydrophobicContact CB-CG2 3.69Å; V45-V60 HydrophobicContact CG1-CG2 3.57Å; V45-V60 HydrophobicContact CG2-CG2 3.97Å; F46-V60 HydrophobicContact CE2-CG1 3.8Å; F46-V60 HydrophobicContact CE2-CG2 4.26Å; F46-V60 HydrophobicContact CZ-CG1 4.1Å; N56-V60 PolarHBondContact O-N 3.19Å; L57-V60 PolarHBondContact O-N 3.47Å; F58-V60 VanDerWaalsContact C-N 3.32Å; V60-L62 PolarHBondContact O-N 2.83Å; V60-A63 PolarHBondContact O-N 3.2Å; V60-S64 PolarHBondContact O-N 3.3Å; V60-S64 PolarHBondContact O-OG 3.38Å; V60-S64 VanDerWaalsContact O-OG 3.07Å
61	S	96.9	Very high	93.7	Very high	12 Å²	12	27.7 Å²	27.7	8%	0.084	15%	0.148	C	C	.	.	H	α-helix	trans	-63.5	-41.1	179.2	-170.5	0	0	0	0	112.2	L57 F58 S64 A65 H110 I141 W145	L57-S61 PolarHBondContact O-N 2.92Å; F58-S61 PolarHBondContact O-N 2.84Å; S61-S64 WeakPolarHBondContact O-CB 3.28Å; S61-S64 PolarHBondContact O-N 3.35Å; S61-A65 PolarHBondContact O-N 3.1Å; S61-H110 VanDerWaalsContact CB-NE2 3.35Å; S61-H110 WeakPolarHBondContact CB-NE2 3.43Å; S61-H110 PolarHBondContact OG-CE1 3.02Å; S61-H110 PolarHBondContact OG-NE2 3.23Å; S61-I141 VanDerWaalsContact OG-CG2 3.29Å; S61-I141 WeakPolarHBondContact OG-CG2 3.14Å; S61-W145 PolarHBondContact OG-NE1 3.39Å
62	L	95.4	Very high	94.2	Very high	1 Å²	1	30.5 Å²	30.5	1%	0.005	16%	0.162	C	C	.	.	H	α-helix	trans	-61.6	-46.1	173.5	-179.9	60.5	0	0	0	111.6	F58 V60 S64 A65 D66 H110 L111 I114 Y398	F58-L62 WeakPolarHBondContact O-CB 3.47Å; F58-L62 PolarHBondContact O-N 2.98Å; V60-L62 PolarHBondContact O-N 2.83Å; L62-S64 VanDerWaalsContact C-N 3.26Å; L62-S64 PolarHBondContact O-N 3.14Å; L62-A65 WeakPolarHBondContact O-CB 3.42Å; L62-A65 PolarHBondContact O-N 3.16Å; L62-A65 VanDerWaalsContact O-N 3.14Å; L62-D66 PolarHBondContact O-N 3.07Å; L62-H110 HydrophobicContact CB-CB 4.39Å; L62-H110 HydrophobicContact CD1-CB 4.21Å; L62-L111 HydrophobicContact CD2-CD2 3.73Å; L62-L111 HydrophobicContact CD2-CG 4.4Å; L62-I114 HydrophobicContact CD2-CD1 4.33Å; L62-Y398 VanDerWaalsContact CD2-OH 3.3Å; L62-Y398 WeakPolarHBondContact CD2-OH 3.43Å
63	A	96.6	Very high	94.7	Very high	1 Å²	1	23.1 Å²	23.1	1%	0.008	13%	0.134	C	C	.	.	H	α-helix	trans	-61.2	-34.9	175	0	0	0	0	0	112.3	N38 V41 V42 L59 V60 D66 I67	N38-A63 HydrophobicContact CB-CB 3.94Å; V41-A63 HydrophobicContact CB-CB 4.26Å; V41-A63 HydrophobicContact CG1-CB 4.12Å; V42-A63 HydrophobicContact CG2-CB 3.92Å; L59-A63 VanDerWaalsContact O-CB 3.24Å; L59-A63 WeakPolarHBondContact O-CB 3.2Å; L59-A63 PolarHBondContact O-N 3.39Å; V60-A63 PolarHBondContact O-N 3.2Å; A63-D66 PolarHBondContact O-N 3.3Å; A63-I67 WeakPolarHBondContact O-CD1 3.5Å; A63-I67 WeakPolarHBondContact O-CG1 3.33Å; A63-I67 PolarHBondContact O-N 2.91Å
64	S	97.3	Very high	95.1	Very high	47 Å²	47	21.8 Å²	21.8	33%	0.329	12%	0.123	S	C	.	.	H	α-helix	trans	-65	-42.9	173.2	-61.1	0	0	0	0	112.2	V60 S61 L62 I67 L68	V60-S64 PolarHBondContact O-N 3.3Å; V60-S64 PolarHBondContact O-OG 3.38Å; V60-S64 VanDerWaalsContact O-OG 3.07Å; S61-S64 WeakPolarHBondContact O-CB 3.28Å; S61-S64 PolarHBondContact O-N 3.35Å; L62-S64 VanDerWaalsContact C-N 3.26Å; L62-S64 PolarHBondContact O-N 3.14Å; S64-I67 PolarHBondContact O-N 3.38Å; S64-L68 VanDerWaalsContact O-CG 3.25Å; S64-L68 WeakPolarHBondContact O-CG 3.42Å; S64-L68 PolarHBondContact O-N 3.36Å
65	A	96.9	Very high	95.5	Very high	0 Å²	0	22.7 Å²	22.7	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-61.1	-45.1	174.8	0	0	0	0	0	111.5	S61 L62 I67 L68 V69 W145	S61-A65 PolarHBondContact O-N 3.1Å; L62-A65 WeakPolarHBondContact O-CB 3.42Å; L62-A65 PolarHBondContact O-N 3.16Å; L62-A65 VanDerWaalsContact O-N 3.14Å; A65-I67 PolarHBondContact O-N 3.26Å; A65-L68 PolarHBondContact O-N 3.16Å; A65-L68 VanDerWaalsContact O-N 3.17Å; A65-V69 WeakPolarHBondContact O-CG2 3.46Å; A65-V69 PolarHBondContact O-N 2.82Å; A65-W145 HydrophobicContact CB-CH2 4.01Å; A65-W145 HydrophobicContact CB-CZ2 4.14Å
66	D	97.1	Very high	95.8	Very high	0 Å²	0	22.5 Å²	22.5	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-61.6	-40.3	177.6	-72.6	-31.9	0	0	0	112.8	I34 L62 A63 V69 A70 S391 N394	I34-D66 HydrophobicContact CG2-CB 4.32Å; I34-D66 WeakPolarHBondContact CG2-O 3.18Å; L62-D66 PolarHBondContact O-N 3.07Å; A63-D66 PolarHBondContact O-N 3.3Å; D66-V69 PolarHBondContact O-N 2.92Å; D66-A70 PolarHBondContact O-N 2.94Å; D66-S391 WeakPolarHBondContact OD1-CA 3.3Å; D66-S391 WeakPolarHBondContact OD1-CB 3.48Å; D66-S391 PolarHBondContact OD1-OG 3.36Å; D66-N394 PolarHBondContact OD2-ND2 3.21Å
67	I	98.1	Very high	95.8	Very high	33 Å²	33	21.8 Å²	21.8	17%	0.169	12%	0.124	C	C	.	.	H	α-helix	trans	-63.1	-44.4	174.4	-69.8	162.8	0	0	0	110.4	N38 V39 A63 S64 A65 V69 A70 T71	N38-I67 HydrophobicContact CB-CD1 3.93Å; N38-I67 HydrophobicContact CB-CG1 3.65Å; V39-I67 HydrophobicContact CG2-CD1 3.82Å; A63-I67 WeakPolarHBondContact O-CD1 3.5Å; A63-I67 WeakPolarHBondContact O-CG1 3.33Å; A63-I67 PolarHBondContact O-N 2.91Å; S64-I67 PolarHBondContact O-N 3.38Å; A65-I67 PolarHBondContact O-N 3.26Å; I67-V69 VanDerWaalsContact C-N 3.34Å; I67-V69 PolarHBondContact O-N 3.47Å; I67-A70 PolarHBondContact O-N 3.49Å; I67-T71 HydrophobicContact CG2-CG2 4.3Å; I67-T71 WeakPolarHBondContact O-CG2 3.48Å; I67-T71 PolarHBondContact O-N 3.35Å; I67-T71 PolarHBondContact O-OG1 3.48Å; I67-T71 VanDerWaalsContact O-OG1 3.07Å
68	L	97.4	Very high	95.8	Very high	57 Å²	57	21 Å²	21	30%	0.298	12%	0.12	S	C	.	.	H	α-helix	trans	-64.7	-36.7	-179.6	-69.4	167.6	0	0	0	112.3	S64 A65 T71 L72 F103 W145	S64-L68 VanDerWaalsContact O-CG 3.25Å; S64-L68 WeakPolarHBondContact O-CG 3.42Å; S64-L68 PolarHBondContact O-N 3.36Å; A65-L68 PolarHBondContact O-N 3.16Å; A65-L68 VanDerWaalsContact O-N 3.17Å; L68-T71 PolarHBondContact O-N 3.06Å; L68-L72 HydrophobicContact CD2-CD1 3.81Å; L68-L72 HydrophobicContact CD2-CG 4.47Å; L68-L72 VanDerWaalsContact O-CB 3.28Å; L68-L72 WeakPolarHBondContact O-CB 2.95Å; L68-L72 PolarHBondContact O-N 3.3Å; L68-F103 HydrophobicContact CB-CD1 4.16Å; L68-F103 HydrophobicContact CB-CD2 4.13Å; L68-F103 HydrophobicContact CB-CE1 3.76Å; L68-F103 HydrophobicContact CB-CE2 3.71Å; L68-F103 HydrophobicContact CB-CG 4.35Å; L68-F103 HydrophobicContact CB-CZ 3.52Å; L68-F103 HydrophobicContact CD1-CD1 4.33Å; L68-F103 HydrophobicContact CD1-CE1 3.6Å; L68-F103 HydrophobicContact CD1-CZ 3.94Å; L68-F103 HydrophobicContact CG-CE1 4.27Å; L68-F103 HydrophobicContact CG-CZ 4.2Å; L68-W145 HydrophobicContact CD1-CH2 4.17Å
69	V	96.6	Very high	95.6	Very high	5 Å²	5	22 Å²	22	3%	0.03	13%	0.128	C	C	.	.	I	π-helix	trans	-58.9	-49.3	170.8	171.8	0	0	0	0	110.7	A65 D66 I67 T71 V73 M74 F103 Y388	A65-V69 WeakPolarHBondContact O-CG2 3.46Å; A65-V69 PolarHBondContact O-N 2.82Å; D66-V69 PolarHBondContact O-N 2.92Å; I67-V69 VanDerWaalsContact C-N 3.34Å; I67-V69 PolarHBondContact O-N 3.47Å; V69-T71 VanDerWaalsContact C-N 3.31Å; V69-T71 PolarHBondContact O-N 3.36Å; V69-V73 WeakPolarHBondContact O-CA 3.42Å; V69-V73 WeakPolarHBondContact O-CB 3.45Å; V69-V73 PolarHBondContact O-N 3.39Å; V69-M74 HydrophobicContact CG1-CG 4.15Å; V69-M74 PolarHBondContact O-N 2.91Å; V69-F103 HydrophobicContact CG2-CB 3.3Å; V69-F103 HydrophobicContact CG2-CD2 3.98Å; V69-F103 HydrophobicContact CG2-CG 3.99Å; V69-Y388 HydrophobicContact CG1-CD1 3.51Å; V69-Y388 HydrophobicContact CG1-CE1 3.64Å
70	A	97.3	Very high	95.4	Very high	0 Å²	0	22.6 Å²	22.6	0%	0	13%	0.132	C	C	.	.	I	π-helix	trans	-66.6	-30.7	-176.8	0	0	0	0	0	113.7	I31 I34 V35 D66 I67 M74 P75	I31-A70 HydrophobicContact CG2-CB 4.34Å; I34-A70 HydrophobicContact CB-CB 3.91Å; I34-A70 HydrophobicContact CD1-CB 4.29Å; I34-A70 HydrophobicContact CG2-CB 3.63Å; V35-A70 HydrophobicContact CG2-CB 3.96Å; D66-A70 PolarHBondContact O-N 2.94Å; I67-A70 PolarHBondContact O-N 3.49Å; A70-M74 HydrophobicContact CB-SD 4.18Å; A70-P75 WeakPolarHBondContact O-CD 3.43Å
71	T	96.5	Very high	95	Very high	62 Å²	62	24.8 Å²	24.8	38%	0.38	14%	0.141	S	C	.	.	I	π-helix	trans	-96.4	-33.4	-176.7	58.6	0	0	0	0	114	V35 I67 L68 V69	V35-T71 HydrophobicContact CG2-CG2 4.02Å; I67-T71 HydrophobicContact CG2-CG2 4.3Å; I67-T71 WeakPolarHBondContact O-CG2 3.48Å; I67-T71 PolarHBondContact O-N 3.35Å; I67-T71 PolarHBondContact O-OG1 3.48Å; I67-T71 VanDerWaalsContact O-OG1 3.07Å; L68-T71 PolarHBondContact O-N 3.06Å; V69-T71 VanDerWaalsContact C-N 3.31Å; V69-T71 PolarHBondContact O-N 3.36Å
72	L	95.6	Very high	94.6	Very high	62 Å²	62	27.1 Å²	27.1	33%	0.325	15%	0.152	S	C	.	.	I	π-helix	trans	-107.7	-17.2	-173.5	-57.3	-178.2	0	0	0	114.1	L68 F76 F103	L68-L72 HydrophobicContact CD2-CD1 3.81Å; L68-L72 HydrophobicContact CD2-CG 4.47Å; L68-L72 VanDerWaalsContact O-CB 3.28Å; L68-L72 WeakPolarHBondContact O-CB 2.95Å; L68-L72 PolarHBondContact O-N 3.3Å; L72-F76 WeakPolarHBondContact O-CD2 3.4Å; L72-F103 HydrophobicContact CB-CE2 4.47Å; L72-F103 HydrophobicContact CD1-CE2 4.39Å; L72-F103 HydrophobicContact CD1-CZ 4.3Å
73	V	95.5	Very high	94.1	Very high	0 Å²	0	30.4 Å²	30.4	0%	0	17%	0.168	C	C	.	.	I	π-helix	trans	-115.2	-53.3	-174.8	-176	0	0	0	0	111.3	V69 F76 S77 Y96 L99 D100 F103 Y388	V69-V73 WeakPolarHBondContact O-CA 3.42Å; V69-V73 WeakPolarHBondContact O-CB 3.45Å; V69-V73 PolarHBondContact O-N 3.39Å; V73-F76 PolarHBondContact O-N 2.65Å; V73-S77 PolarHBondContact O-N 2.9Å; V73-S77 PolarHBondContact O-OG 2.88Å; V73-Y96 HydrophobicContact CG1-CD2 4.27Å; V73-Y96 HydrophobicContact CG1-CE2 3.74Å; V73-L99 HydrophobicContact CG2-CB 4.27Å; V73-D100 HydrophobicContact CG1-CB 3.68Å; V73-D100 HydrophobicContact CG2-CB 4.44Å; V73-F103 HydrophobicContact CG2-CD2 3.83Å; V73-F103 HydrophobicContact CG2-CE2 4.09Å; V73-Y388 HydrophobicContact CG1-CE1 4.23Å; V73-Y388 WeakPolarHBondContact CG1-OH 3.46Å
74	M	95.6	Very high	93.4	Very high	3 Å²	3	32.9 Å²	32.9	2%	0.015	19%	0.194	C	C	.	.	H	α-helix	trans	-59.4	-40.4	-175.6	-66.8	-178	71.5	0	0	114.4	V27 M30 I31 I34 V69 A70 F76 S77 L78 W385 Y388	V27-M74 HydrophobicContact CG1-CE 4.14Å; M30-M74 HydrophobicContact CB-CE 4.15Å; I31-M74 HydrophobicContact CD1-CB 3.91Å; I31-M74 HydrophobicContact CG1-CB 3.92Å; I31-M74 HydrophobicContact CG1-CE 3.91Å; I31-M74 HydrophobicContact CG1-SD 3.96Å; I34-M74 HydrophobicContact CD1-CE 4.14Å; I34-M74 HydrophobicContact CD1-SD 3.54Å; I34-M74 VanDerWaalsContact CD1-SD 3.54Å; V69-M74 HydrophobicContact CG1-CG 4.15Å; V69-M74 PolarHBondContact O-N 2.91Å; A70-M74 HydrophobicContact CB-SD 4.18Å; M74-F76 PolarHBondContact O-N 3.27Å; M74-S77 WeakPolarHBondContact O-CB 3.36Å; M74-S77 PolarHBondContact O-N 3.36Å; M74-L78 WeakPolarHBondContact O-CB 3.12Å; M74-L78 PolarHBondContact O-N 2.93Å; M74-W385 HydrophobicContact CE-CE3 4.49Å; M74-W385 HydrophobicContact CE-CZ3 3.98Å; M74-Y388 HydrophobicContact CG-CD1 4.26Å; M74-Y388 HydrophobicContact CG-CD2 4.25Å; M74-Y388 HydrophobicContact CG-CE1 4.49Å; M74-Y388 HydrophobicContact CG-CE2 4.48Å; M74-Y388 HydrophobicContact CG-CG 4.14Å; M74-Y388 HydrophobicContact SD-CG 4.39Å
75	P	95.2	Very high	92.7	Very high	50 Å²	50	34.8 Å²	34.8	33%	0.325	19%	0.194	S	C	.	.	H	α-helix	trans	-65	-39.3	179.2	-23.1	35.7	0	0	0	112.6	I31 A70 L78 A79	I31-P75 HydrophobicContact CD1-CG 4.16Å; A70-P75 WeakPolarHBondContact O-CD 3.43Å; P75-L78 PolarHBondContact O-N 3.48Å; P75-A79 WeakPolarHBondContact O-CB 3.4Å; P75-A79 PolarHBondContact O-N 3.07Å
76	F	94.3	Very high	92.2	Very high	43 Å²	43	35 Å²	35	19%	0.189	20%	0.195	C	C	.	.	H	α-helix	trans	-74	-35.6	177.9	-65.1	-81.7	0	0	0	111.8	L72 V73 M74 L78 A79 N80 W86 F88 W92 Y96	L72-F76 WeakPolarHBondContact O-CD2 3.4Å; V73-F76 PolarHBondContact O-N 2.65Å; M74-F76 PolarHBondContact O-N 3.27Å; F76-L78 VanDerWaalsContact C-N 3.32Å; F76-L78 PolarHBondContact O-N 3.26Å; F76-A79 PolarHBondContact O-N 3.28Å; F76-N80 WeakPolarHBondContact O-CB 3.19Å; F76-N80 PolarHBondContact O-N 3.33Å; F76-W86 HydrophobicContact CB-CH2 4.16Å; F76-W86 HydrophobicContact CB-CZ3 4.45Å; F76-F88 AromaticContact CD1-CD2 3.95Å; F76-F88 HydrophobicContact CD1-CD2 3.95Å; F76-F88 HydrophobicContact CD1-CE1 4.41Å; F76-F88 AromaticContact CD1-CE2 3.76Å; F76-F88 HydrophobicContact CD1-CE2 3.76Å; F76-F88 HydrophobicContact CD1-CG 4.36Å; F76-F88 HydrophobicContact CD1-CZ 4.01Å; F76-F88 HydrophobicContact CE1-CD1 4.17Å; F76-F88 HydrophobicContact CE1-CD2 4.34Å; F76-F88 AromaticContact CE1-CE1 3.99Å; F76-F88 HydrophobicContact CE1-CE1 3.99Å; F76-F88 HydrophobicContact CE1-CE2 4.17Å; F76-F88 HydrophobicContact CE1-CG 4.35Å; F76-F88 AromaticContact CE1-CZ 3.99Å; F76-F88 HydrophobicContact CE1-CZ 3.99Å; F76-W92 AromaticContact CD1-CD1 3.99Å; F76-W92 AromaticContact CD1-NE1 3.22Å; F76-W92 HydrophobicContact CD2-CZ2 4.34Å; F76-W92 AromaticContact CE1-CD1 4Å; F76-W92 AromaticContact CE1-CE2 3.84Å; F76-W92 HydrophobicContact CE1-CZ2 4.12Å; F76-W92 AromaticContact CE1-NE1 3.1Å; F76-W92 AromaticContact CE2-CZ2 3.7Å; F76-W92 HydrophobicContact CE2-CZ2 3.7Å; F76-W92 AromaticContact CE2-NE1 4Å; F76-W92 AromaticContact CG-NE1 3.72Å; F76-W92 AromaticContact CZ-CE2 3.79Å; F76-W92 AromaticContact CZ-CZ2 3.57Å; F76-W92 HydrophobicContact CZ-CZ2 3.57Å; F76-W92 AromaticContact CZ-NE1 3.52Å; F76-Y96 HydrophobicContact CB-CD2 3.91Å; F76-Y96 HydrophobicContact CB-CE2 4.13Å
77	S	92.6	Very high	91.8	Very high	5 Å²	5	43.2 Å²	43.2	4%	0.035	23%	0.227	C	C	.	.	H	α-helix	trans	-58.3	-45.6	170	-57.6	0	0	0	0	111.1	V73 M74 E81 Y96 Y388	V73-S77 PolarHBondContact O-N 2.9Å; V73-S77 PolarHBondContact O-OG 2.88Å; M74-S77 WeakPolarHBondContact O-CB 3.36Å; M74-S77 PolarHBondContact O-N 3.36Å; S77-E81 PolarHBondContact O-N 3.39Å; S77-E81 VanDerWaalsContact O-N 3.11Å; S77-Y96 WeakPolarHBondContact OG-CE2 3.41Å; S77-Y96 PolarHBondContact OG-OH 2.95Å; S77-Y388 PolarHBondContact OG-OH 2.92Å
78	L	92.8	Very high	91.3	Very high	22 Å²	22	45.6 Å²	45.6	12%	0.115	24%	0.236	C	C	.	.	H	α-helix	trans	-65.3	-44.4	177.2	178.8	63.1	0	0	0	111.3	L23 P24 V27 M74 P75 F76 N80 E81 L82 W385	L23-L78 HydrophobicContact CD2-CD1 4.16Å; L23-L78 HydrophobicContact CG-CD1 4.01Å; P24-L78 HydrophobicContact CB-CD2 4.27Å; V27-L78 HydrophobicContact CB-CD1 4.24Å; V27-L78 HydrophobicContact CB-CD2 4.16Å; V27-L78 HydrophobicContact CG1-CB 4.22Å; V27-L78 HydrophobicContact CG1-CD1 4.45Å; V27-L78 HydrophobicContact CG1-CD2 3.98Å; V27-L78 HydrophobicContact CG1-CG 4.45Å; V27-L78 HydrophobicContact CG2-CD1 4.22Å; M74-L78 WeakPolarHBondContact O-CB 3.12Å; M74-L78 PolarHBondContact O-N 2.93Å; P75-L78 PolarHBondContact O-N 3.48Å; F76-L78 VanDerWaalsContact C-N 3.32Å; F76-L78 PolarHBondContact O-N 3.26Å; L78-N80 VanDerWaalsContact C-N 3.34Å; L78-N80 PolarHBondContact O-N 3.47Å; L78-E81 PolarHBondContact O-N 3.48Å; L78-L82 HydrophobicContact CD1-CD1 3.9Å; L78-L82 HydrophobicContact CD1-CD2 4.44Å; L78-L82 HydrophobicContact CD1-CG 3.98Å; L78-L82 HydrophobicContact CD2-CD1 4.41Å; L78-L82 HydrophobicContact CG-CD1 3.8Å; L78-L82 HydrophobicContact CG-CG 4.28Å; L78-L82 VanDerWaalsContact O-CG 3.3Å; L78-L82 WeakPolarHBondContact O-CG 3.2Å; L78-L82 PolarHBondContact O-N 3.27Å; L78-W385 HydrophobicContact CB-CH2 4.03Å; L78-W385 HydrophobicContact CB-CZ2 4.44Å
79	A	91.3	Very high	90.7	Very high	22 Å²	22	44.5 Å²	44.5	18%	0.182	24%	0.239	C	C	.	.	H	α-helix	trans	-60.2	-44.3	178.2	0	0	0	0	0	111.6	P75 F76 E81 L82 M83 F88	P75-A79 WeakPolarHBondContact O-CB 3.4Å; P75-A79 PolarHBondContact O-N 3.07Å; F76-A79 PolarHBondContact O-N 3.28Å; A79-E81 VanDerWaalsContact C-N 3.3Å; A79-E81 PolarHBondContact O-N 2.98Å; A79-L82 PolarHBondContact O-N 3.37Å; A79-M83 HydrophobicContact CB-CE 4Å; A79-M83 WeakPolarHBondContact O-CB 3.38Å; A79-M83 WeakPolarHBondContact O-CG 3.31Å; A79-M83 PolarHBondContact O-N 3.49Å; A79-F88 HydrophobicContact CB-CE2 4.15Å
80	N	88.6	Confident	90.1	Very high	35 Å²	35	48.9 Å²	48.9	19%	0.187	26%	0.263	C	S	.	.	H	α-helix	trans	-59.7	-40.5	175	-167.6	53.4	0	0	0	111.8	F76 L78 G84 W86 C175	F76-N80 WeakPolarHBondContact O-CB 3.19Å; F76-N80 PolarHBondContact O-N 3.33Å; L78-N80 VanDerWaalsContact C-N 3.34Å; L78-N80 PolarHBondContact O-N 3.47Å; N80-G84 PolarHBondContact O-N 2.95Å; N80-G84 VanDerWaalsContact O-N 3.13Å; N80-W86 HydrophobicContact CB-CE3 4.01Å; N80-W86 HydrophobicContact CB-CZ3 4.03Å; N80-C175 PolarHBondContact ND2-O 2.92Å
81	E	87.8	Confident	89.5	Confident	60 Å²	60	54 Å²	54	28%	0.28	29%	0.294	S	S	.	.	H	α-helix	trans	-69.4	-39.3	178.8	-169.6	60.1	-152.1	0	0	113	L23 S77 L78 A79 K381	L23-E81 HydrophobicContact CD2-CB 4.43Å; L23-E81 HydrophobicContact CD2-CG 3.67Å; S77-E81 PolarHBondContact O-N 3.39Å; S77-E81 VanDerWaalsContact O-N 3.11Å; L78-E81 PolarHBondContact O-N 3.48Å; A79-E81 VanDerWaalsContact C-N 3.3Å; A79-E81 PolarHBondContact O-N 2.98Å; E81-K381 IonicContact OE1-NZ 3.9Å; E81-K381 PolarHBondContact OE1-NZ 3.49Å; E81-K381 VanDerWaalsContact OE2-CD 3.3Å; E81-K381 WeakPolarHBondContact OE2-CD 3.42Å; E81-K381 WeakPolarHBondContact OE2-CE 3.31Å; E81-K381 IonicContact OE2-NZ 2.65Å; E81-K381 PolarHBondContact OE2-NZ 3.2Å
82	L	88.1	Confident	89.2	Confident	62 Å²	62	54.7 Å²	54.7	33%	0.325	29%	0.289	S	S	.	.	H	α-helix	trans	-78.3	-39.6	-177	-66.7	173.1	0	0	0	113.1	L23 P24 L78 A79	L23-L82 HydrophobicContact CD2-CD2 4.43Å; P24-L82 HydrophobicContact CB-CD1 4.44Å; P24-L82 HydrophobicContact CG-CD1 3.78Å; P24-L82 HydrophobicContact CG-CD2 3.8Å; P24-L82 HydrophobicContact CG-CG 4.4Å; L78-L82 HydrophobicContact CD1-CD1 3.9Å; L78-L82 HydrophobicContact CD1-CD2 4.44Å; L78-L82 HydrophobicContact CD1-CG 3.98Å; L78-L82 HydrophobicContact CD2-CD1 4.41Å; L78-L82 HydrophobicContact CG-CD1 3.8Å; L78-L82 HydrophobicContact CG-CG 4.28Å; L78-L82 VanDerWaalsContact O-CG 3.3Å; L78-L82 WeakPolarHBondContact O-CG 3.2Å; L78-L82 PolarHBondContact O-N 3.27Å; A79-L82 PolarHBondContact O-N 3.37Å
83	M	85.6	Confident	88.9	Confident	70 Å²	70	52.5 Å²	52.5	35%	0.345	28%	0.279	S	S	.	.	H	α-helix	trans	-78.9	-30.8	-178.5	-65.9	-169.7	-64.6	0	0	111.5	A79 Y85 F88	A79-M83 HydrophobicContact CB-CE 4Å; A79-M83 WeakPolarHBondContact O-CB 3.38Å; A79-M83 WeakPolarHBondContact O-CG 3.31Å; A79-M83 PolarHBondContact O-N 3.49Å; M83-Y85 HydrophobicContact CB-CD1 4.24Å; M83-Y85 HydrophobicContact CB-CE1 4.11Å; M83-Y85 WeakPolarHBondContact O-CD1 3.45Å; M83-Y85 PolarHBondContact O-N 3.32Å; M83-F88 HydrophobicContact CE-CE2 4.07Å
84	G	81.7	Confident	88.4	Confident	52 Å²	52	54.5 Å²	54.5	54%	0.536	29%	0.288	S	S	.	.	S	Bend	trans	72.8	0.8	-176.2	0	0	0	0	0	114.1	N80	N80-G84 PolarHBondContact O-N 2.95Å; N80-G84 VanDerWaalsContact O-N 3.13Å
85	Y	81.5	Confident	88.1	Confident	88 Å²	88	57 Å²	57	35%	0.345	30%	0.301	S	S	.	.	S	Bend	trans	-145.3	163.2	171.4	66.7	-86.8	0	0	0	109.1	M83	M83-Y85 HydrophobicContact CB-CD1 4.24Å; M83-Y85 HydrophobicContact CB-CE1 4.11Å; M83-Y85 WeakPolarHBondContact O-CD1 3.45Å; M83-Y85 PolarHBondContact O-N 3.32Å
86	W	87.7	Confident	88	Confident	4 Å²	4	55.1 Å²	55.1	2%	0.015	29%	0.288	C	S	.	.			trans	-100.3	113.5	-176.2	-174	-105.7	0	0	0	112	F76 N80 F88 G89 W92 C93 Y96 P173 C175	F76-W86 HydrophobicContact CB-CH2 4.16Å; F76-W86 HydrophobicContact CB-CZ3 4.45Å; N80-W86 HydrophobicContact CB-CE3 4.01Å; N80-W86 HydrophobicContact CB-CZ3 4.03Å; W86-F88 HydrophobicContact CD2-CD2 4.3Å; W86-F88 HydrophobicContact CE3-CD2 4.31Å; W86-F88 HydrophobicContact CH2-CD2 4.16Å; W86-F88 HydrophobicContact CZ2-CB 4.03Å; W86-F88 HydrophobicContact CZ2-CD2 4.12Å; W86-F88 HydrophobicContact CZ3-CD2 4.24Å; W86-G89 PolarHBondContact NE1-O 2.84Å; W86-W92 AromaticContact CH2-CD1 4Å; W86-W92 HydrophobicContact CZ2-CB 4.41Å; W86-W92 AromaticContact CZ2-CD1 3.46Å; W86-W92 VanDerWaalsContact CZ2-CD1 3.46Å; W86-W92 HydrophobicContact CZ2-CG 4.26Å; W86-C93 HydrophobicContact CZ2-CB 4.04Å; W86-Y96 AromaticContact CH2-CD1 3.72Å; W86-Y96 HydrophobicContact CH2-CD1 3.72Å; W86-Y96 HydrophobicContact CH2-CE1 4.32Å; W86-Y96 AromaticContact CH2-CG 3.88Å; W86-Y96 HydrophobicContact CH2-CG 3.88Å; W86-Y96 HydrophobicContact CZ2-CD1 4.38Å; W86-Y96 HydrophobicContact CZ3-CD1 4.27Å; W86-Y96 HydrophobicContact CZ3-CE1 4.45Å; W86-P173 WeakPolarHBondContact CB-O 3.47Å; W86-P173 PolarHBondContact N-O 2.91Å; W86-P173 WeakPolarHBondContact O-CG 3.22Å; W86-C175 HydrophobicContact CB-CB 3.8Å; W86-C175 HydrophobicContact CD2-CB 3.33Å; W86-C175 HydrophobicContact CE3-CB 3.47Å; W86-C175 VanDerWaalsContact CE3-CB 3.47Å; W86-C175 HydrophobicContact CG-CB 3.51Å; W86-C175 HydrophobicContact CZ2-CB 4.44Å; W86-C175 HydrophobicContact CZ3-CB 4.09Å
87	Y	87.3	Confident	87.8	Confident	173 Å²	173	54.5 Å²	54.5	68%	0.678	29%	0.286	S	S	*	.			trans	-86.5	-26.9	-177.3	179.5	-98.2	0	0	0	114.1	G89	Y87-G89 PolarHBondContact O-N 3.45Å; Y87-G89 VanDerWaalsContact O-N 3.15Å
88	F	88.3	Confident	87.8	Confident	82 Å²	82	54.5 Å²	54.5	36%	0.36	29%	0.286	S	S	.	.	S	Bend	trans	-82.2	7.9	-163.3	-57.4	-77.9	0	0	0	115.2	F76 A79 M83 W86 W92	F76-F88 AromaticContact CD1-CD2 3.95Å; F76-F88 HydrophobicContact CD1-CD2 3.95Å; F76-F88 HydrophobicContact CD1-CE1 4.41Å; F76-F88 AromaticContact CD1-CE2 3.76Å; F76-F88 HydrophobicContact CD1-CE2 3.76Å; F76-F88 HydrophobicContact CD1-CG 4.36Å; F76-F88 HydrophobicContact CD1-CZ 4.01Å; F76-F88 HydrophobicContact CE1-CD1 4.17Å; F76-F88 HydrophobicContact CE1-CD2 4.34Å; F76-F88 AromaticContact CE1-CE1 3.99Å; F76-F88 HydrophobicContact CE1-CE1 3.99Å; F76-F88 HydrophobicContact CE1-CE2 4.17Å; F76-F88 HydrophobicContact CE1-CG 4.35Å; F76-F88 AromaticContact CE1-CZ 3.99Å; F76-F88 HydrophobicContact CE1-CZ 3.99Å; A79-F88 HydrophobicContact CB-CE2 4.15Å; M83-F88 HydrophobicContact CE-CE2 4.07Å; W86-F88 HydrophobicContact CD2-CD2 4.3Å; W86-F88 HydrophobicContact CE3-CD2 4.31Å; W86-F88 HydrophobicContact CH2-CD2 4.16Å; W86-F88 HydrophobicContact CZ2-CB 4.03Å; W86-F88 HydrophobicContact CZ2-CD2 4.12Å; W86-F88 HydrophobicContact CZ3-CD2 4.24Å; F88-W92 HydrophobicContact CB-CB 3.94Å; F88-W92 VanDerWaalsContact CB-CD1 3.43Å; F88-W92 HydrophobicContact CB-CG 3.95Å; F88-W92 AromaticContact CG-CD1 3.91Å; F88-W92 VanDerWaalsContact O-CB 3.31Å; F88-W92 WeakPolarHBondContact O-CB 3.29Å
89	G	86.1	Confident	87.8	Confident	35 Å²	35	55 Å²	55	36%	0.361	29%	0.289	S	S	.	.			trans	77	162.5	-177.8	0	0	0	0	0	114.1	W86 Y87 W92 C93	W86-G89 PolarHBondContact NE1-O 2.84Å; Y87-G89 PolarHBondContact O-N 3.45Å; Y87-G89 VanDerWaalsContact O-N 3.15Å; G89-W92 PolarHBondContact O-N 3.42Å; G89-C93 PolarHBondContact O-N 3.38Å; G89-C93 VanDerWaalsContact O-N 3.16Å
90	D	82.9	Confident	87.9	Confident	97 Å²	97	54.5 Å²	54.5	52%	0.519	28%	0.283	S	S	.	.	H	α-helix	trans	-67.4	-40.6	-170.1	-59.1	-48.1	0	0	0	112.6	W92 C93 E94	D90-W92 VanDerWaalsContact C-N 3.27Å; D90-W92 PolarHBondContact O-N 3.44Å; D90-C93 WeakPolarHBondContact O-CA 3.37Å; D90-C93 VanDerWaalsContact O-CB 3.3Å; D90-C93 WeakPolarHBondContact O-CB 3.25Å; D90-C93 PolarHBondContact O-N 3.03Å; D90-E94 PolarHBondContact O-N 3.47Å
91	V	85	Confident	88.2	Confident	107 Å²	107	54.2 Å²	54.2	65%	0.648	28%	0.283	S	S	*	.	H	α-helix	trans	-55.5	-43.5	176.1	179.8	0	0	0	0	111.4	E94 I95	V91-E94 PolarHBondContact O-N 2.76Å; V91-I95 HydrophobicContact CG1-CD1 3.98Å; V91-I95 WeakPolarHBondContact O-CG1 3.47Å; V91-I95 PolarHBondContact O-N 2.94Å; V91-I95 VanDerWaalsContact O-N 3.13Å
92	W	89.6	Confident	88.5	Confident	77 Å²	77	52.1 Å²	52.1	29%	0.292	27%	0.273	S	S	.	.	H	α-helix	trans	-71.3	-34.4	178.3	-169.1	-112.1	0	0	0	112	F76 W86 F88 G89 D90 E94 I95 Y96	F76-W92 AromaticContact CD1-CD1 3.99Å; F76-W92 AromaticContact CD1-NE1 3.22Å; F76-W92 HydrophobicContact CD2-CZ2 4.34Å; F76-W92 AromaticContact CE1-CD1 4Å; F76-W92 AromaticContact CE1-CE2 3.84Å; F76-W92 HydrophobicContact CE1-CZ2 4.12Å; F76-W92 AromaticContact CE1-NE1 3.1Å; F76-W92 AromaticContact CE2-CZ2 3.7Å; F76-W92 HydrophobicContact CE2-CZ2 3.7Å; F76-W92 AromaticContact CE2-NE1 4Å; F76-W92 AromaticContact CG-NE1 3.72Å; F76-W92 AromaticContact CZ-CE2 3.79Å; F76-W92 AromaticContact CZ-CZ2 3.57Å; F76-W92 HydrophobicContact CZ-CZ2 3.57Å; F76-W92 AromaticContact CZ-NE1 3.52Å; W86-W92 AromaticContact CH2-CD1 4Å; W86-W92 HydrophobicContact CZ2-CB 4.41Å; W86-W92 AromaticContact CZ2-CD1 3.46Å; W86-W92 VanDerWaalsContact CZ2-CD1 3.46Å; W86-W92 HydrophobicContact CZ2-CG 4.26Å; F88-W92 HydrophobicContact CB-CB 3.94Å; F88-W92 VanDerWaalsContact CB-CD1 3.43Å; F88-W92 HydrophobicContact CB-CG 3.95Å; F88-W92 AromaticContact CG-CD1 3.91Å; F88-W92 VanDerWaalsContact O-CB 3.31Å; F88-W92 WeakPolarHBondContact O-CB 3.29Å; G89-W92 PolarHBondContact O-N 3.42Å; D90-W92 VanDerWaalsContact C-N 3.27Å; D90-W92 PolarHBondContact O-N 3.44Å; W92-E94 VanDerWaalsContact C-N 3.31Å; W92-E94 PolarHBondContact O-N 2.96Å; W92-I95 HydrophobicContact CE3-CB 4.3Å; W92-I95 HydrophobicContact CE3-CD1 4.23Å; W92-I95 HydrophobicContact CE3-CG2 4.2Å; W92-I95 HydrophobicContact CZ3-CG2 3.98Å; W92-I95 PolarHBondContact O-N 3.03Å; W92-Y96 WeakPolarHBondContact O-CB 3.21Å; W92-Y96 PolarHBondContact O-N 3.27Å
93	C	88.9	Confident	88.9	Confident	16 Å²	16	49.5 Å²	49.5	11%	0.108	26%	0.259	C	S	.	.	H	α-helix	trans	-57.9	-46.5	174.2	176.9	0	0	0	0	110.9	W86 G89 D90 Y96 L97 C175	W86-C93 HydrophobicContact CZ2-CB 4.04Å; G89-C93 PolarHBondContact O-N 3.38Å; G89-C93 VanDerWaalsContact O-N 3.16Å; D90-C93 WeakPolarHBondContact O-CA 3.37Å; D90-C93 VanDerWaalsContact O-CB 3.3Å; D90-C93 WeakPolarHBondContact O-CB 3.25Å; D90-C93 PolarHBondContact O-N 3.03Å; C93-Y96 PolarHBondContact O-N 3.25Å; C93-L97 WeakPolarHBondContact O-CB 3.38Å; C93-L97 VanDerWaalsContact O-CG 3.28Å; C93-L97 WeakPolarHBondContact O-CG 3.42Å; C93-L97 PolarHBondContact O-N 3.49Å; C93-C175 WeakPolarHBondContact CA-SG 3.4Å; C93-C175 HydrophobicContact CB-CB 3.81Å; C93-C175 WeakPolarHBondContact CB-SG 3.4Å; C93-C175 WeakPolarHBondContact SG-CA 3.36Å; C93-C175 WeakPolarHBondContact SG-CB 3.49Å; C93-C175 CovalentContact SG-SG 2.03Å; C93-C175 PolarHBondContact SG-SG 2.94Å
94	E	85.9	Confident	89.2	Confident	41 Å²	41	46.5 Å²	46.5	19%	0.192	25%	0.245	C	C	.	.	H	α-helix	trans	-64.6	-44.7	179.5	-63.5	-174.3	172.3	0	0	112.4	D90 V91 W92 L97 A98 L156 M159	D90-E94 PolarHBondContact O-N 3.47Å; V91-E94 PolarHBondContact O-N 2.76Å; W92-E94 VanDerWaalsContact C-N 3.31Å; W92-E94 PolarHBondContact O-N 2.96Å; E94-L97 PolarHBondContact O-N 3.11Å; E94-A98 VanDerWaalsContact O-CB 3.29Å; E94-A98 WeakPolarHBondContact O-CB 3.3Å; E94-A98 PolarHBondContact O-N 3.3Å; E94-L156 HydrophobicContact CB-CD2 3.58Å; E94-L156 HydrophobicContact CB-CG 4.27Å; E94-M159 VanDerWaalsContact OE1-CB 3.24Å; E94-M159 WeakPolarHBondContact OE1-CB 3.4Å
95	I	90	Very high	89.9	Confident	57 Å²	57	44 Å²	44	29%	0.292	22%	0.22	S	C	.	.	H	α-helix	trans	-61.3	-47.2	176.6	-68.2	168.6	0	0	0	110	V91 W92 L97 A98 L99 L156	V91-I95 HydrophobicContact CG1-CD1 3.98Å; V91-I95 WeakPolarHBondContact O-CG1 3.47Å; V91-I95 PolarHBondContact O-N 2.94Å; V91-I95 VanDerWaalsContact O-N 3.13Å; W92-I95 HydrophobicContact CE3-CB 4.3Å; W92-I95 HydrophobicContact CE3-CD1 4.23Å; W92-I95 HydrophobicContact CE3-CG2 4.2Å; W92-I95 HydrophobicContact CZ3-CG2 3.98Å; W92-I95 PolarHBondContact O-N 3.03Å; I95-L97 PolarHBondContact O-N 2.91Å; I95-A98 PolarHBondContact O-N 3.38Å; I95-L99 HydrophobicContact CG2-CD1 3.85Å; I95-L99 HydrophobicContact CG2-CG 4.16Å; I95-L99 WeakPolarHBondContact O-CB 3.39Å; I95-L99 VanDerWaalsContact O-CG 3.25Å; I95-L99 WeakPolarHBondContact O-CG 3.38Å; I95-L99 PolarHBondContact O-N 3.27Å; I95-L156 HydrophobicContact CG1-CD2 4.04Å
96	Y	91.8	Very high	90.6	Very high	10 Å²	10	39.8 Å²	39.8	4%	0.039	20%	0.203	C	C	.	.	H	α-helix	trans	-57.2	-49.7	178.5	153.8	-106	0	0	0	111.9	V73 F76 S77 W86 W92 C93 A98 L99 D100	V73-Y96 HydrophobicContact CG1-CD2 4.27Å; V73-Y96 HydrophobicContact CG1-CE2 3.74Å; F76-Y96 HydrophobicContact CB-CD2 3.91Å; F76-Y96 HydrophobicContact CB-CE2 4.13Å; S77-Y96 WeakPolarHBondContact OG-CE2 3.41Å; S77-Y96 PolarHBondContact OG-OH 2.95Å; W86-Y96 AromaticContact CH2-CD1 3.72Å; W86-Y96 HydrophobicContact CH2-CD1 3.72Å; W86-Y96 HydrophobicContact CH2-CE1 4.32Å; W86-Y96 AromaticContact CH2-CG 3.88Å; W86-Y96 HydrophobicContact CH2-CG 3.88Å; W86-Y96 HydrophobicContact CZ2-CD1 4.38Å; W86-Y96 HydrophobicContact CZ3-CD1 4.27Å; W86-Y96 HydrophobicContact CZ3-CE1 4.45Å; W92-Y96 WeakPolarHBondContact O-CB 3.21Å; W92-Y96 PolarHBondContact O-N 3.27Å; C93-Y96 PolarHBondContact O-N 3.25Å; Y96-A98 VanDerWaalsContact C-N 3.35Å; Y96-A98 PolarHBondContact O-N 3.33Å; Y96-L99 PolarHBondContact O-N 2.97Å; Y96-D100 PolarHBondContact O-N 3.46Å
97	L	90.1	Very high	90.9	Very high	29 Å²	29	39.8 Å²	39.8	15%	0.152	20%	0.204	C	C	.	.	H	α-helix	trans	-65.1	-38.5	179	-68.4	173.4	0	0	0	112	C93 E94 I95 V101 K176 I177	C93-L97 WeakPolarHBondContact O-CB 3.38Å; C93-L97 VanDerWaalsContact O-CG 3.28Å; C93-L97 WeakPolarHBondContact O-CG 3.42Å; C93-L97 PolarHBondContact O-N 3.49Å; E94-L97 PolarHBondContact O-N 3.11Å; I95-L97 PolarHBondContact O-N 2.91Å; L97-V101 WeakPolarHBondContact O-CG2 3.35Å; L97-V101 PolarHBondContact O-N 3.14Å; L97-K176 VanDerWaalsContact CD1-O 3.28Å; L97-K176 WeakPolarHBondContact CD1-O 3.38Å; L97-I177 HydrophobicContact CD2-CG1 4.11Å
98	A	92.3	Very high	91.2	Very high	5 Å²	5	31.6 Å²	31.6	4%	0.041	17%	0.172	C	C	.	.	H	α-helix	trans	-67.5	-40	176	0	0	0	0	0	112.1	E94 I95 Y96 V101 L102 S152 L156	E94-A98 VanDerWaalsContact O-CB 3.29Å; E94-A98 WeakPolarHBondContact O-CB 3.3Å; E94-A98 PolarHBondContact O-N 3.3Å; I95-A98 PolarHBondContact O-N 3.38Å; Y96-A98 VanDerWaalsContact C-N 3.35Å; Y96-A98 PolarHBondContact O-N 3.33Å; A98-V101 PolarHBondContact O-N 3.36Å; A98-L102 WeakPolarHBondContact O-CB 3.44Å; A98-L102 PolarHBondContact O-N 2.96Å; A98-S152 WeakPolarHBondContact O-CB 3.22Å; A98-L156 HydrophobicContact CB-CD1 3.31Å; A98-L156 HydrophobicContact CB-CG 4.06Å
99	L	94.1	Very high	91.5	Very high	33 Å²	33	28.6 Å²	28.6	17%	0.173	16%	0.16	C	C	.	.	H	α-helix	trans	-64.5	-40.1	176.2	-74.1	178.1	0	0	0	112	V73 I95 Y96 L102 F103	V73-L99 HydrophobicContact CG2-CB 4.27Å; I95-L99 HydrophobicContact CG2-CD1 3.85Å; I95-L99 HydrophobicContact CG2-CG 4.16Å; I95-L99 WeakPolarHBondContact O-CB 3.39Å; I95-L99 VanDerWaalsContact O-CG 3.25Å; I95-L99 WeakPolarHBondContact O-CG 3.38Å; I95-L99 PolarHBondContact O-N 3.27Å; Y96-L99 PolarHBondContact O-N 2.97Å; L99-L102 HydrophobicContact CD2-CD2 4.03Å; L99-L102 WeakPolarHBondContact O-CB 3.32Å; L99-L102 PolarHBondContact O-N 2.79Å; L99-F103 HydrophobicContact CB-CD2 4.36Å; L99-F103 HydrophobicContact CB-CE2 3.89Å; L99-F103 HydrophobicContact CB-CZ 4.49Å; L99-F103 HydrophobicContact CD2-CE2 4.04Å; L99-F103 HydrophobicContact CD2-CZ 3.77Å; L99-F103 HydrophobicContact CG-CE2 4.4Å; L99-F103 WeakPolarHBondContact O-CD2 3.03Å; L99-F103 VanDerWaalsContact O-CG 3.31Å; L99-F103 WeakPolarHBondContact O-CG 2.99Å; L99-F103 PolarHBondContact O-N 3.14Å
100	D	93.8	Very high	91.9	Very high	11 Å²	11	27 Å²	27	6%	0.059	14%	0.143	C	C	.	.	H	α-helix	trans	-59.7	-51.8	175.9	-173.9	26	0	0	0	111.4	V73 Y96 L102 F103 C104 F384 Y388	V73-D100 HydrophobicContact CG1-CB 3.68Å; V73-D100 HydrophobicContact CG2-CB 4.44Å; Y96-D100 PolarHBondContact O-N 3.46Å; D100-L102 VanDerWaalsContact C-N 3.33Å; D100-L102 PolarHBondContact O-N 2.99Å; D100-F103 PolarHBondContact O-N 3.38Å; D100-C104 WeakPolarHBondContact O-CB 3.41Å; D100-C104 PolarHBondContact O-N 3.31Å; D100-F384 VanDerWaalsContact OD2-CE2 3.23Å; D100-F384 WeakPolarHBondContact OD2-CE2 3.28Å; D100-F384 VanDerWaalsContact OD2-CZ 3.28Å; D100-F384 WeakPolarHBondContact OD2-CZ 3.38Å; D100-Y388 PolarHBondContact OD1-OH 3.48Å
101	V	92.9	Very high	92.3	Very high	29 Å²	29	22.6 Å²	22.6	18%	0.176	12%	0.12	C	C	.	.	H	α-helix	trans	-62	-41.2	176.2	177.7	0	0	0	0	111.3	L97 A98 T105	L97-V101 WeakPolarHBondContact O-CG2 3.35Å; L97-V101 PolarHBondContact O-N 3.14Å; A98-V101 PolarHBondContact O-N 3.36Å; V101-T105 WeakPolarHBondContact O-CB 3.25Å; V101-T105 PolarHBondContact O-N 3.01Å; V101-T105 PolarHBondContact O-OG1 2.91Å
102	L	95.3	Very high	92.6	Very high	16 Å²	16	18 Å²	18	8%	0.084	9%	0.092	C	C	.	.	H	α-helix	trans	-57.8	-53.6	178.5	173.9	68.9	0	0	0	111	A98 L99 D100 T105 A106 W145 A148 A149	A98-L102 WeakPolarHBondContact O-CB 3.44Å; A98-L102 PolarHBondContact O-N 2.96Å; L99-L102 HydrophobicContact CD2-CD2 4.03Å; L99-L102 WeakPolarHBondContact O-CB 3.32Å; L99-L102 PolarHBondContact O-N 2.79Å; D100-L102 VanDerWaalsContact C-N 3.33Å; D100-L102 PolarHBondContact O-N 2.99Å; L102-T105 PolarHBondContact O-N 3.43Å; L102-A106 VanDerWaalsContact O-CB 3.25Å; L102-A106 WeakPolarHBondContact O-CB 3.16Å; L102-A106 PolarHBondContact O-N 3.01Å; L102-W145 HydrophobicContact CD2-CZ3 4.43Å; L102-W145 HydrophobicContact CG-CZ3 4.36Å; L102-A148 HydrophobicContact CD1-CB 3.79Å; L102-A149 HydrophobicContact CD1-CB 4.1Å; L102-A149 VanDerWaalsContact CD1-N 3.3Å
103	F	95.8	Very high	92.8	Very high	7 Å²	7	15 Å²	15	3%	0.031	8%	0.083	C	C	.	.	H	α-helix	trans	-72.9	-35.2	-174.4	-59.9	-42.5	0	0	0	112.2	L68 V69 L72 V73 L99 D100 A106 S107 W145	L68-F103 HydrophobicContact CB-CD1 4.16Å; L68-F103 HydrophobicContact CB-CD2 4.13Å; L68-F103 HydrophobicContact CB-CE1 3.76Å; L68-F103 HydrophobicContact CB-CE2 3.71Å; L68-F103 HydrophobicContact CB-CG 4.35Å; L68-F103 HydrophobicContact CB-CZ 3.52Å; L68-F103 HydrophobicContact CD1-CD1 4.33Å; L68-F103 HydrophobicContact CD1-CE1 3.6Å; L68-F103 HydrophobicContact CD1-CZ 3.94Å; L68-F103 HydrophobicContact CG-CE1 4.27Å; L68-F103 HydrophobicContact CG-CZ 4.2Å; V69-F103 HydrophobicContact CG2-CB 3.3Å; V69-F103 HydrophobicContact CG2-CD2 3.98Å; V69-F103 HydrophobicContact CG2-CG 3.99Å; L72-F103 HydrophobicContact CB-CE2 4.47Å; L72-F103 HydrophobicContact CD1-CE2 4.39Å; L72-F103 HydrophobicContact CD1-CZ 4.3Å; V73-F103 HydrophobicContact CG2-CD2 3.83Å; V73-F103 HydrophobicContact CG2-CE2 4.09Å; L99-F103 HydrophobicContact CB-CD2 4.36Å; L99-F103 HydrophobicContact CB-CE2 3.89Å; L99-F103 HydrophobicContact CB-CZ 4.49Å; L99-F103 HydrophobicContact CD2-CE2 4.04Å; L99-F103 HydrophobicContact CD2-CZ 3.77Å; L99-F103 HydrophobicContact CG-CE2 4.4Å; L99-F103 WeakPolarHBondContact O-CD2 3.03Å; L99-F103 VanDerWaalsContact O-CG 3.31Å; L99-F103 WeakPolarHBondContact O-CG 2.99Å; L99-F103 PolarHBondContact O-N 3.14Å; D100-F103 PolarHBondContact O-N 3.38Å; F103-A106 PolarHBondContact O-N 2.95Å; F103-S107 WeakPolarHBondContact O-CB 3.04Å; F103-S107 PolarHBondContact O-N 3.05Å; F103-S107 PolarHBondContact O-OG 3.21Å; F103-S107 VanDerWaalsContact O-OG 3.12Å; F103-W145 AromaticContact CD1-CH2 3.87Å; F103-W145 HydrophobicContact CD1-CH2 3.87Å; F103-W145 AromaticContact CD1-CZ3 3.81Å; F103-W145 HydrophobicContact CD1-CZ3 3.81Å; F103-W145 HydrophobicContact CE1-CH2 4.02Å; F103-W145 AromaticContact CE1-CZ3 3.88Å; F103-W145 HydrophobicContact CE1-CZ3 3.88Å
104	C	93.4	Very high	92.9	Very high	7 Å²	7	15.2 Å²	15.2	5%	0.047	8%	0.083	C	C	.	.	H	α-helix	trans	-61.8	-47.9	171.5	-176.8	0	0	0	0	111.3	D100 A106 S107 I108 W357	D100-C104 WeakPolarHBondContact O-CB 3.41Å; D100-C104 PolarHBondContact O-N 3.31Å; C104-A106 VanDerWaalsContact C-N 3.35Å; C104-A106 PolarHBondContact O-N 3.23Å; C104-S107 PolarHBondContact O-N 2.89Å; C104-I108 PolarHBondContact O-N 3.4Å; C104-W357 HydrophobicContact CB-CH2 3.97Å; C104-W357 HydrophobicContact CB-CZ2 4.2Å; C104-W357 HydrophobicContact CB-CZ3 4.41Å; C104-W357 VanDerWaalsContact SG-CH2 3.55Å; C104-W357 VanDerWaalsContact SG-CZ3 3.57Å
105	T	94.8	Very high	93	Very high	0 Å²	0	13.5 Å²	13.5	0%	0	8%	0.076	C	C	.	.	H	α-helix	trans	-62.6	-41.7	177.4	-56	0	0	0	0	111.6	V101 L102 I108 T109 A148 I151 S191	V101-T105 WeakPolarHBondContact O-CB 3.25Å; V101-T105 PolarHBondContact O-N 3.01Å; V101-T105 PolarHBondContact O-OG1 2.91Å; L102-T105 PolarHBondContact O-N 3.43Å; T105-I108 WeakPolarHBondContact O-CG2 3.45Å; T105-T109 VanDerWaalsContact O-CB 3.22Å; T105-T109 WeakPolarHBondContact O-CB 3.47Å; T105-T109 PolarHBondContact O-N 3.23Å; T105-T109 PolarHBondContact O-OG1 3.36Å; T105-A148 HydrophobicContact CG2-CB 3.88Å; T105-I151 HydrophobicContact CG2-CB 4.41Å; T105-I151 HydrophobicContact CG2-CD1 3.94Å; T105-I151 HydrophobicContact CG2-CG2 4.49Å; T105-S191 WeakPolarHBondContact OG1-CB 3.45Å
106	A	96.2	Very high	93	Very high	0 Å²	0	12.9 Å²	12.9	0%	0	7%	0.073	C	C	.	.	H	α-helix	trans	-60.9	-45.8	175.5	0	0	0	0	0	110.4	L102 F103 C104 T109 H110 W145 A148	L102-A106 VanDerWaalsContact O-CB 3.25Å; L102-A106 WeakPolarHBondContact O-CB 3.16Å; L102-A106 PolarHBondContact O-N 3.01Å; F103-A106 PolarHBondContact O-N 2.95Å; C104-A106 VanDerWaalsContact C-N 3.35Å; C104-A106 PolarHBondContact O-N 3.23Å; A106-T109 PolarHBondContact O-N 3.41Å; A106-H110 WeakPolarHBondContact O-CB 3.43Å; A106-H110 PolarHBondContact O-N 2.88Å; A106-H110 PolarHBondContact O-ND1 3.31Å; A106-W145 HydrophobicContact CB-CE3 4.24Å; A106-W145 HydrophobicContact CB-CH2 4.29Å; A106-W145 HydrophobicContact CB-CZ3 4.08Å; A106-A148 HydrophobicContact CB-CB 3.94Å
107	S	94.1	Very high	92.9	Very high	4 Å²	4	13 Å²	13	3%	0.028	7%	0.074	C	C	.	.	H	α-helix	trans	-60	-51.6	-177.8	-73.8	0	0	0	0	113	F103 C104 H110 L111	F103-S107 WeakPolarHBondContact O-CB 3.04Å; F103-S107 PolarHBondContact O-N 3.05Å; F103-S107 PolarHBondContact O-OG 3.21Å; F103-S107 VanDerWaalsContact O-OG 3.12Å; C104-S107 PolarHBondContact O-N 2.89Å; S107-H110 PolarHBondContact O-N 3.49Å; S107-L111 WeakPolarHBondContact O-CG 3.36Å; S107-L111 PolarHBondContact O-N 3.36Å
108	I	93.2	Very high	92.7	Very high	1 Å²	1	13.7 Å²	13.7	1%	0.005	8%	0.075	C	C	.	.	H	α-helix	trans	-67.9	-37.2	178.1	-169.9	179.5	0	0	0	112.9	C104 T105 H110 L111 C112 S191 F192 P195 C196 M199 F353	C104-I108 PolarHBondContact O-N 3.4Å; T105-I108 WeakPolarHBondContact O-CG2 3.45Å; I108-H110 VanDerWaalsContact C-N 3.31Å; I108-H110 PolarHBondContact O-N 3.41Å; I108-L111 WeakPolarHBondContact O-CB 3.49Å; I108-L111 PolarHBondContact O-N 3.44Å; I108-L111 VanDerWaalsContact O-N 3.15Å; I108-C112 WeakPolarHBondContact O-CB 3.41Å; I108-C112 PolarHBondContact O-N 3.29Å; I108-S191 WeakPolarHBondContact CG2-O 3.45Å; I108-F192 HydrophobicContact CD1-CD2 4Å; I108-F192 WeakPolarHBondContact CD1-O 3.39Å; I108-P195 HydrophobicContact CD1-CB 3.81Å; I108-P195 HydrophobicContact CG1-CB 3.93Å; I108-P195 HydrophobicContact CG2-CB 4.37Å; I108-P195 HydrophobicContact CG2-CG 4.48Å; I108-C196 HydrophobicContact CD1-CB 4.23Å; I108-M199 HydrophobicContact CG1-SD 3.93Å; I108-F353 HydrophobicContact CB-CD1 4.43Å; I108-F353 HydrophobicContact CB-CE1 3.7Å; I108-F353 HydrophobicContact CB-CE2 4.05Å; I108-F353 HydrophobicContact CB-CZ 3.49Å; I108-F353 VanDerWaalsContact CB-CZ 3.49Å; I108-F353 HydrophobicContact CD1-CD1 4.16Å; I108-F353 HydrophobicContact CD1-CE1 3.56Å; I108-F353 HydrophobicContact CD1-CZ 4.23Å; I108-F353 HydrophobicContact CG1-CD1 4.11Å; I108-F353 HydrophobicContact CG1-CE1 3.67Å; I108-F353 HydrophobicContact CG1-CZ 4.03Å; I108-F353 HydrophobicContact CG2-CZ 4.35Å
109	T	94.6	Very high	92.5	Very high	19 Å²	19	16.7 Å²	16.7	12%	0.117	9%	0.086	C	C	.	.	H	α-helix	trans	-67.8	-33.7	177.6	-53.5	0	0	0	0	111.1	T105 A106 C112 A113 V144	T105-T109 VanDerWaalsContact O-CB 3.22Å; T105-T109 WeakPolarHBondContact O-CB 3.47Å; T105-T109 PolarHBondContact O-N 3.23Å; T105-T109 PolarHBondContact O-OG1 3.36Å; A106-T109 PolarHBondContact O-N 3.41Å; T109-C112 WeakPolarHBondContact O-CB 3.15Å; T109-C112 PolarHBondContact O-N 2.03Å; T109-A113 WeakPolarHBondContact O-CB 3.42Å; T109-A113 PolarHBondContact O-N 2.9Å; T109-V144 HydrophobicContact CG2-CB 4.27Å; T109-V144 HydrophobicContact CG2-CG1 3.71Å; T109-V144 HydrophobicContact CG2-CG2 3.97Å
110	H	94.7	Very high	92.3	Very high	0 Å²	0	19.6 Å²	19.6	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-63.9	-43.9	168.9	-80.6	93.7	0	0	0	111.8	S61 L62 A106 S107 I108 C112 A113 I114 V144 W145	S61-H110 VanDerWaalsContact CB-NE2 3.35Å; S61-H110 WeakPolarHBondContact CB-NE2 3.43Å; S61-H110 PolarHBondContact OG-CE1 3.02Å; S61-H110 PolarHBondContact OG-NE2 3.23Å; L62-H110 HydrophobicContact CB-CB 4.39Å; L62-H110 HydrophobicContact CD1-CB 4.21Å; A106-H110 WeakPolarHBondContact O-CB 3.43Å; A106-H110 PolarHBondContact O-N 2.88Å; A106-H110 PolarHBondContact O-ND1 3.31Å; S107-H110 PolarHBondContact O-N 3.49Å; I108-H110 VanDerWaalsContact C-N 3.31Å; I108-H110 PolarHBondContact O-N 3.41Å; H110-C112 VanDerWaalsContact C-N 3.27Å; H110-C112 PolarHBondContact O-N 2.87Å; H110-A113 PolarHBondContact O-N 3.37Å; H110-I114 VanDerWaalsContact O-CG1 3.24Å; H110-I114 WeakPolarHBondContact O-CG1 3.47Å; H110-I114 PolarHBondContact O-N 3.23Å; H110-V144 WeakPolarHBondContact CE1-CG1 3.41Å; H110-V144 WeakPolarHBondContact ND1-CG1 3.27Å; H110-W145 AromaticContact CE1-NE1 3.61Å; H110-W145 AromaticContact NE2-NE1 3.9Å
111	L	91.1	Very high	91.8	Very high	5 Å²	5	20.3 Å²	20.3	3%	0.026	10%	0.1	C	C	.	.	H	α-helix	trans	-61.9	-36.6	174.8	-67.8	178.6	0	0	0	112.1	L62 S107 I108 I114 S115 M199 V349 F353	L62-L111 HydrophobicContact CD2-CD2 3.73Å; L62-L111 HydrophobicContact CD2-CG 4.4Å; S107-L111 WeakPolarHBondContact O-CG 3.36Å; S107-L111 PolarHBondContact O-N 3.36Å; I108-L111 WeakPolarHBondContact O-CB 3.49Å; I108-L111 PolarHBondContact O-N 3.44Å; I108-L111 VanDerWaalsContact O-N 3.15Å; L111-I114 HydrophobicContact CD2-CD1 4.42Å; L111-I114 PolarHBondContact O-N 2.88Å; L111-S115 WeakPolarHBondContact O-CB 3.24Å; L111-S115 PolarHBondContact O-N 3.14Å; L111-S115 PolarHBondContact O-OG 2.62Å; L111-M199 HydrophobicContact CB-CE 3.5Å; L111-M199 HydrophobicContact CB-SD 3.99Å; L111-M199 HydrophobicContact CD1-CE 4.48Å; L111-V349 HydrophobicContact CD1-CG1 4.36Å; L111-V349 HydrophobicContact CD2-CG1 3.43Å; L111-V349 VanDerWaalsContact CD2-CG1 3.43Å; L111-F353 HydrophobicContact CD1-CB 3.73Å; L111-F353 HydrophobicContact CD1-CD2 3.45Å; L111-F353 VanDerWaalsContact CD1-CD2 3.45Å; L111-F353 HydrophobicContact CD1-CE2 4.31Å; L111-F353 HydrophobicContact CD1-CG 3.65Å
112	C	92.9	Very high	91.3	Very high	12 Å²	12	20.1 Å²	20.1	8%	0.081	10%	0.098	C	C	.	.	H	α-helix	trans	-64.1	-47.5	173.1	-171.5	0	0	0	0	111.5	I108 T109 H110 I114 S115 L116 I198 M199	I108-C112 WeakPolarHBondContact O-CB 3.41Å; I108-C112 PolarHBondContact O-N 3.29Å; T109-C112 WeakPolarHBondContact O-CB 3.15Å; T109-C112 PolarHBondContact O-N 2.03Å; H110-C112 VanDerWaalsContact C-N 3.27Å; H110-C112 PolarHBondContact O-N 2.87Å; C112-I114 VanDerWaalsContact C-N 3.35Å; C112-I114 PolarHBondContact O-N 2.93Å; C112-S115 WeakPolarHBondContact O-CB 3.34Å; C112-S115 PolarHBondContact O-N 3.49Å; C112-S115 VanDerWaalsContact O-N 3.14Å; C112-L116 WeakPolarHBondContact O-CG 3.43Å; C112-L116 PolarHBondContact O-N 3.14Å; C112-I198 VanDerWaalsContact SG-CG2 3.56Å; C112-M199 HydrophobicContact CB-CG 3.63Å; C112-M199 HydrophobicContact CB-SD 3.82Å; C112-M199 PolarHBondContact N-SD 2.88Å
113	A	92.8	Very high	90.8	Very high	12 Å²	12	21.3 Å²	21.3	10%	0.099	11%	0.106	C	C	.	.	H	α-helix	trans	-60.4	-41.5	175.5	0	0	0	0	0	112.4	F58 T109 H110 S115 L116 D117 I140 V144	F58-A113 HydrophobicContact CE1-CB 4.15Å; T109-A113 WeakPolarHBondContact O-CB 3.42Å; T109-A113 PolarHBondContact O-N 2.9Å; H110-A113 PolarHBondContact O-N 3.37Å; A113-S115 VanDerWaalsContact C-N 3.33Å; A113-S115 PolarHBondContact O-N 3.42Å; A113-L116 PolarHBondContact O-N 3.22Å; A113-D117 WeakPolarHBondContact O-CB 3.41Å; A113-D117 PolarHBondContact O-N 3.43Å; A113-I140 HydrophobicContact CB-CG2 4.24Å; A113-V144 HydrophobicContact CB-CG2 4.25Å
114	I	90.8	Very high	90.2	Very high	21 Å²	21	25.4 Å²	25.4	11%	0.108	13%	0.125	C	C	.	.	H	α-helix	trans	-61.9	-42.5	174.5	-69.1	163.1	0	0	0	110.7	F58 L59 L62 H110 L111 C112 D117 R118 L346	F58-I114 HydrophobicContact CB-CD1 3.95Å; F58-I114 HydrophobicContact CB-CG1 3.56Å; F58-I114 HydrophobicContact CD2-CG1 4.3Å; F58-I114 HydrophobicContact CG-CG1 4.02Å; L59-I114 HydrophobicContact CD2-CD1 4.04Å; L62-I114 HydrophobicContact CD2-CD1 4.33Å; H110-I114 VanDerWaalsContact O-CG1 3.24Å; H110-I114 WeakPolarHBondContact O-CG1 3.47Å; H110-I114 PolarHBondContact O-N 3.23Å; L111-I114 HydrophobicContact CD2-CD1 4.42Å; L111-I114 PolarHBondContact O-N 2.88Å; C112-I114 VanDerWaalsContact C-N 3.35Å; C112-I114 PolarHBondContact O-N 2.93Å; I114-D117 PolarHBondContact O-N 3.45Å; I114-R118 WeakPolarHBondContact O-CB 3.15Å; I114-R118 PolarHBondContact O-N 3.29Å; I114-L346 HydrophobicContact CG2-CD2 3.72Å
115	S	88.8	Confident	89.5	Confident	5 Å²	5	27.8 Å²	27.8	4%	0.035	15%	0.145	C	C	.	.	H	α-helix	trans	-64.5	-41.4	178.8	-59.3	0	0	0	0	111.6	L111 C112 A113 R118 Y119	L111-S115 WeakPolarHBondContact O-CB 3.24Å; L111-S115 PolarHBondContact O-N 3.14Å; L111-S115 PolarHBondContact O-OG 2.62Å; C112-S115 WeakPolarHBondContact O-CB 3.34Å; C112-S115 PolarHBondContact O-N 3.49Å; C112-S115 VanDerWaalsContact O-N 3.14Å; A113-S115 VanDerWaalsContact C-N 3.33Å; A113-S115 PolarHBondContact O-N 3.42Å; S115-R118 PolarHBondContact O-N 3.48Å; S115-Y119 PolarHBondContact O-N 2.85Å
116	L	90.8	Very high	88.7	Confident	45 Å²	45	34.5 Å²	34.5	24%	0.236	18%	0.18	C	C	.	.	H	α-helix	trans	-68.1	-45.3	175.8	-73.8	169.7	0	0	0	112.4	C112 A113 R118 Y119 W120 V202	C112-L116 WeakPolarHBondContact O-CG 3.43Å; C112-L116 PolarHBondContact O-N 3.14Å; A113-L116 PolarHBondContact O-N 3.22Å; L116-R118 PolarHBondContact O-N 3Å; L116-Y119 WeakPolarHBondContact O-CB 3.35Å; L116-Y119 PolarHBondContact O-N 3.38Å; L116-Y119 VanDerWaalsContact O-N 3.07Å; L116-W120 VanDerWaalsContact C-CE3 3.47Å; L116-W120 HydrophobicContact CB-CE3 4.05Å; L116-W120 HydrophobicContact CB-CH2 3.9Å; L116-W120 HydrophobicContact CB-CZ3 3.55Å; L116-W120 HydrophobicContact CD1-CH2 4.3Å; L116-W120 HydrophobicContact CD2-CH2 4.18Å; L116-W120 HydrophobicContact CD2-CZ2 4.37Å; L116-W120 HydrophobicContact CG-CH2 4.37Å; L116-W120 HydrophobicContact CG-CZ3 4.49Å; L116-W120 PolarHBondContact O-N 3.34Å; L116-V202 HydrophobicContact CD2-CG2 3.55Å; L116-V202 HydrophobicContact CG-CG2 4.33Å
117	D	89.8	Confident	88	Confident	12 Å²	12	39.5 Å²	39.5	6%	0.064	20%	0.203	C	C	.	.	H	α-helix	trans	-55.2	-41	172.2	179.1	76.1	0	0	0	110.8	F58 A113 I114 S121 Y128	F58-D117 HydrophobicContact CE2-CB 4.11Å; A113-D117 WeakPolarHBondContact O-CB 3.41Å; A113-D117 PolarHBondContact O-N 3.43Å; I114-D117 PolarHBondContact O-N 3.45Å; D117-S121 WeakPolarHBondContact O-CB 3.38Å; D117-S121 PolarHBondContact O-N 3.49Å; D117-S121 PolarHBondContact O-OG 2.75Å; D117-Y128 VanDerWaalsContact OD1-CE1 3.27Å; D117-Y128 WeakPolarHBondContact OD1-CE1 3.45Å; D117-Y128 PolarHBondContact OD1-OH 3.28Å
118	R	85.4	Confident	87.5	Confident	43 Å²	43	39.8 Å²	39.8	16%	0.162	20%	0.203	C	C	.	.	H	α-helix	trans	-66.3	-44.7	175.9	-175	56.9	168.7	-174.2	6.7	112.1	I114 S115 L116 W120 S121 I122 I206 F342 L346	I114-R118 WeakPolarHBondContact O-CB 3.15Å; I114-R118 PolarHBondContact O-N 3.29Å; S115-R118 PolarHBondContact O-N 3.48Å; L116-R118 PolarHBondContact O-N 3Å; R118-W120 PolarHBondContact O-N 2.83Å; R118-S121 WeakPolarHBondContact CA-OG 3.35Å; R118-S121 PolarHBondContact O-N 2.94Å; R118-S121 PolarHBondContact O-OG 3.21Å; R118-I122 HydrophobicContact CG-CD1 3.76Å; R118-I122 HydrophobicContact CG-CG1 4.29Å; R118-I122 WeakPolarHBondContact O-CG1 3.37Å; R118-I122 PolarHBondContact O-N 3.46Å; R118-I206 HydrophobicContact CG-CD1 4.34Å; R118-F342 HydrophobicContact CG-CE1 4.24Å; R118-F342 VanDerWaalsContact CZ-CE1 3.41Å; R118-F342 VanDerWaalsContact NH2-CD1 3.29Å; R118-L346 HydrophobicContact CB-CD1 3.68Å; R118-L346 HydrophobicContact CG-CD1 3.49Å; R118-L346 VanDerWaalsContact CG-CD1 3.49Å
119	Y	87.5	Confident	86.9	Confident	69 Å²	69	44.1 Å²	44.1	27%	0.271	23%	0.227	S	C	.	.	H	α-helix	trans	-56.7	-50.6	177.4	174.1	-103.8	0	0	0	111.4	S115 L116 S121 I122 T123 V202 R205 I206 I209	S115-Y119 PolarHBondContact O-N 2.85Å; L116-Y119 WeakPolarHBondContact O-CB 3.35Å; L116-Y119 PolarHBondContact O-N 3.38Å; L116-Y119 VanDerWaalsContact O-N 3.07Å; Y119-S121 PolarHBondContact O-N 3.11Å; Y119-I122 PolarHBondContact O-N 3Å; Y119-T123 HydrophobicContact CD2-CG2 3.91Å; Y119-T123 HydrophobicContact CE1-CG2 4.33Å; Y119-T123 HydrophobicContact CE2-CG2 3.55Å; Y119-T123 HydrophobicContact CG-CG2 4.44Å; Y119-T123 WeakPolarHBondContact O-CB 3.42Å; Y119-T123 WeakPolarHBondContact O-CG2 3.47Å; Y119-T123 PolarHBondContact O-N 2.86Å; Y119-T123 PolarHBondContact O-OG1 3.22Å; Y119-V202 HydrophobicContact CD2-CG1 4.49Å; Y119-V202 HydrophobicContact CG-CG1 4.22Å; Y119-R205 HydrophobicContact CE2-CB 4.05Å; Y119-I206 HydrophobicContact CD2-CG1 3.8Å; Y119-I206 HydrophobicContact CG-CG1 4.46Å; Y119-I209 HydrophobicContact CE2-CD1 3.98Å
120	W	88.9	Confident	86.2	Confident	94 Å²	94	50 Å²	50	36%	0.356	26%	0.257	S	S	.	.	H	α-helix	trans	-65.6	-38.3	178.7	-68.5	-54.4	0	0	0	112.7	L116 R118 I122 T123 Q124 Y128	L116-W120 VanDerWaalsContact C-CE3 3.47Å; L116-W120 HydrophobicContact CB-CE3 4.05Å; L116-W120 HydrophobicContact CB-CH2 3.9Å; L116-W120 HydrophobicContact CB-CZ3 3.55Å; L116-W120 HydrophobicContact CD1-CH2 4.3Å; L116-W120 HydrophobicContact CD2-CH2 4.18Å; L116-W120 HydrophobicContact CD2-CZ2 4.37Å; L116-W120 HydrophobicContact CG-CH2 4.37Å; L116-W120 HydrophobicContact CG-CZ3 4.49Å; L116-W120 PolarHBondContact O-N 3.34Å; R118-W120 PolarHBondContact O-N 2.83Å; W120-I122 VanDerWaalsContact C-N 3.32Å; W120-I122 PolarHBondContact O-N 3.4Å; W120-T123 WeakPolarHBondContact CA-OG1 3.42Å; W120-T123 PolarHBondContact O-N 3.43Å; W120-T123 PolarHBondContact O-OG1 3.16Å; W120-Q124 CarbonylContact O-C 3.56Å; W120-Q124 WeakPolarHBondContact O-CA 3.44Å; W120-Q124 PolarHBondContact O-N 3.08Å; W120-Y128 HydrophobicContact CB-CD1 4.02Å; W120-Y128 HydrophobicContact CB-CD2 3.58Å; W120-Y128 HydrophobicContact CB-CE1 4.07Å; W120-Y128 HydrophobicContact CB-CE2 3.64Å; W120-Y128 HydrophobicContact CB-CG 3.78Å; W120-Y128 HydrophobicContact CD2-CE2 4.38Å; W120-Y128 HydrophobicContact CE3-CE2 4.18Å; W120-Y128 HydrophobicContact CG-CD2 4.31Å; W120-Y128 HydrophobicContact CG-CE2 4.2Å
121	S	84.3	Confident	85.7	Confident	26 Å²	26	55 Å²	55	18%	0.182	28%	0.279	C	S	.	.	H	α-helix	trans	-68	-26.7	176	64	0	0	0	0	114.2	D117 R118 Y119 A125	D117-S121 WeakPolarHBondContact O-CB 3.38Å; D117-S121 PolarHBondContact O-N 3.49Å; D117-S121 PolarHBondContact O-OG 2.75Å; R118-S121 WeakPolarHBondContact CA-OG 3.35Å; R118-S121 PolarHBondContact O-N 2.94Å; R118-S121 PolarHBondContact O-OG 3.21Å; Y119-S121 PolarHBondContact O-N 3.11Å; S121-A125 VanDerWaalsContact O-CA 3.3Å; S121-A125 WeakPolarHBondContact O-CA 3.19Å; S121-A125 WeakPolarHBondContact O-CB 3.37Å
122	I	83.1	Confident	85.4	Confident	24 Å²	24	57.3 Å²	57.3	12%	0.123	29%	0.287	C	S	.	.	H	α-helix	trans	-81.7	-42.7	174.5	-68.5	173.3	0	0	0	111.4	R118 Y119 W120 I206 R213	R118-I122 HydrophobicContact CG-CD1 3.76Å; R118-I122 HydrophobicContact CG-CG1 4.29Å; R118-I122 WeakPolarHBondContact O-CG1 3.37Å; R118-I122 PolarHBondContact O-N 3.46Å; Y119-I122 PolarHBondContact O-N 3Å; W120-I122 VanDerWaalsContact C-N 3.32Å; W120-I122 PolarHBondContact O-N 3.4Å; I122-I206 HydrophobicContact CD1-CG2 3.61Å; I122-R213 PolarHBondContact O-NH1 3.35Å; I122-R213 PolarHBondContact O-NH2 3.18Å
123	T	84.3	Confident	85.3	Confident	42 Å²	42	59.8 Å²	59.8	26%	0.258	30%	0.302	S	S	.	.	H	α-helix	trans	-77.9	-41.7	-174.6	52.9	0	0	0	0	112.5	Y119 W120 I209	Y119-T123 HydrophobicContact CD2-CG2 3.91Å; Y119-T123 HydrophobicContact CE1-CG2 4.33Å; Y119-T123 HydrophobicContact CE2-CG2 3.55Å; Y119-T123 HydrophobicContact CG-CG2 4.44Å; Y119-T123 WeakPolarHBondContact O-CB 3.42Å; Y119-T123 WeakPolarHBondContact O-CG2 3.47Å; Y119-T123 PolarHBondContact O-N 2.86Å; Y119-T123 PolarHBondContact O-OG1 3.22Å; W120-T123 WeakPolarHBondContact CA-OG1 3.42Å; W120-T123 PolarHBondContact O-N 3.43Å; W120-T123 PolarHBondContact O-OG1 3.16Å; T123-I209 HydrophobicContact CG2-CD1 3.52Å
124	Q	82.8	Confident	85.1	Confident	93 Å²	93	62.5 Å²	62.5	44%	0.435	32%	0.319	S	S	.	.	S	Bend	trans	-120.3	54.9	-176.4	-63.4	176.7	-4.7	0	0	111	W120 I126 Y128	W120-Q124 CarbonylContact O-C 3.56Å; W120-Q124 WeakPolarHBondContact O-CA 3.44Å; W120-Q124 PolarHBondContact O-N 3.08Å; Q124-I126 VanDerWaalsContact C-N 3.28Å; Q124-I126 PolarHBondContact O-N 3.29Å; Q124-I126 VanDerWaalsContact O-N 3.08Å; Q124-Y128 WeakPolarHBondContact O-CB 3.38Å; Q124-Y128 PolarHBondContact O-N 3.11Å
125	A	77.8	Confident	85.2	Confident	56 Å²	56	72.1 Å²	72.1	46%	0.463	35%	0.353	S	S	.	.	T	Hydrogen-bonded Turn	trans	-56.5	-31.1	-166.4	0	0	0	0	0	116.2	S121 N129	S121-A125 VanDerWaalsContact O-CA 3.3Å; S121-A125 WeakPolarHBondContact O-CA 3.19Å; S121-A125 WeakPolarHBondContact O-CB 3.37Å; A125-N129 WeakPolarHBondContact O-CB 3.5Å
126	I	77.9	Confident	85.3	Confident	141 Å²	141	77.4 Å²	77.4	72%	0.723	37%	0.372	S	S	*	.	T	Hydrogen-bonded Turn	trans	-88.8	-56.8	-178.6	-62	173.2	0	0	0	110.3	Q124 Y128 N129 L130	Q124-I126 VanDerWaalsContact C-N 3.28Å; Q124-I126 PolarHBondContact O-N 3.29Å; Q124-I126 VanDerWaalsContact O-N 3.08Å; I126-Y128 PolarHBondContact O-N 3.27Å; I126-N129 PolarHBondContact O-N 3.2Å; I126-L130 HydrophobicContact CG2-CD1 4.48Å; I126-L130 WeakPolarHBondContact O-CG 3.43Å; I126-L130 PolarHBondContact O-N 3.29Å
127	E	82.9	Confident	85.4	Confident	105 Å²	105	75.3 Å²	75.3	49%	0.491	36%	0.362	S	S	.	.	H	α-helix	trans	-65.1	-42.6	-174.8	-167.3	-175.1	162.1	0	0	112.6	L130 K131	E127-L130 PolarHBondContact O-N 3.09Å; E127-K131 HydrophobicContact CG-CD 4.37Å; E127-K131 WeakPolarHBondContact O-CG 3.35Å; E127-K131 PolarHBondContact O-N 3.06Å; E127-K131 IonicContact OE1-NZ 3.95Å; E127-K131 PolarHBondContact OE1-NZ 2.93Å
128	Y	83.6	Confident	85.7	Confident	10 Å²	10	81.2 Å²	81.2	4%	0.039	39%	0.387	C	S	.	.	H	α-helix	trans	-69.4	-36	179.8	-174.4	-101.7	0	0	0	112.2	D117 W120 Q124 I126 L130 K131 R132	D117-Y128 VanDerWaalsContact OD1-CE1 3.27Å; D117-Y128 WeakPolarHBondContact OD1-CE1 3.45Å; D117-Y128 PolarHBondContact OD1-OH 3.28Å; W120-Y128 HydrophobicContact CB-CD1 4.02Å; W120-Y128 HydrophobicContact CB-CD2 3.58Å; W120-Y128 HydrophobicContact CB-CE1 4.07Å; W120-Y128 HydrophobicContact CB-CE2 3.64Å; W120-Y128 HydrophobicContact CB-CG 3.78Å; W120-Y128 HydrophobicContact CD2-CE2 4.38Å; W120-Y128 HydrophobicContact CE3-CE2 4.18Å; W120-Y128 HydrophobicContact CG-CD2 4.31Å; W120-Y128 HydrophobicContact CG-CE2 4.2Å; Q124-Y128 WeakPolarHBondContact O-CB 3.38Å; Q124-Y128 PolarHBondContact O-N 3.11Å; I126-Y128 PolarHBondContact O-N 3.27Å; Y128-L130 VanDerWaalsContact C-N 3.31Å; Y128-L130 PolarHBondContact O-N 3.32Å; Y128-K131 CarbonylContact O-C 3.56Å; Y128-K131 PolarHBondContact O-N 3.44Å; Y128-K131 VanDerWaalsContact O-N 3.14Å; Y128-R132 WeakPolarHBondContact O-CB 3.33Å; Y128-R132 PolarHBondContact O-N 3.13Å
129	N	80.2	Confident	86.1	Confident	92 Å²	92	82.4 Å²	82.4	49%	0.492	40%	0.401	S	S	.	.	H	α-helix	trans	-66.2	-35.3	179.5	-166.1	1.2	0	0	0	111.7	A125 I126 R132	A125-N129 WeakPolarHBondContact O-CB 3.5Å; I126-N129 PolarHBondContact O-N 3.2Å; N129-R132 PolarHBondContact O-N 3.44Å; N129-R132 PolarHBondContact OD1-NH2 2.75Å
130	L	80.6	Confident	86.5	Confident	143 Å²	143	81 Å²	81	75%	0.749	40%	0.398	S	S	*	.	H	α-helix	trans	-67.4	-35.5	172.3	-66.9	171.8	0	0	0	112.3	I126 E127 Y128 R132	I126-L130 HydrophobicContact CG2-CD1 4.48Å; I126-L130 WeakPolarHBondContact O-CG 3.43Å; I126-L130 PolarHBondContact O-N 3.29Å; E127-L130 PolarHBondContact O-N 3.09Å; Y128-L130 VanDerWaalsContact C-N 3.31Å; Y128-L130 PolarHBondContact O-N 3.32Å; L130-R132 VanDerWaalsContact C-N 3.33Å
131	K	84	Confident	86.9	Confident	106 Å²	106	77.7 Å²	77.7	46%	0.461	39%	0.387	S	S	.	.	H	α-helix	trans	-80.3	-9.4	178.7	-69.4	174.8	176	176.2	0	113.9	E127 Y128 T133	E127-K131 HydrophobicContact CG-CD 4.37Å; E127-K131 WeakPolarHBondContact O-CG 3.35Å; E127-K131 PolarHBondContact O-N 3.06Å; E127-K131 IonicContact OE1-NZ 3.95Å; E127-K131 PolarHBondContact OE1-NZ 2.93Å; Y128-K131 CarbonylContact O-C 3.56Å; Y128-K131 PolarHBondContact O-N 3.44Å; Y128-K131 VanDerWaalsContact O-N 3.14Å; K131-T133 PolarHBondContact O-N 2.93Å
132	R	83.9	Confident	87.5	Confident	52 Å²	52	83 Å²	83	20%	0.196	41%	0.407	C	S	.	.			trans	-80.6	80	-175.4	-169.3	176.6	60.3	-178.2	-2.4	111.4	Q55 Y128 N129 L130 I137	Q55-R132 VanDerWaalsContact CD-NH1 3.26Å; Y128-R132 WeakPolarHBondContact O-CB 3.33Å; Y128-R132 PolarHBondContact O-N 3.13Å; N129-R132 PolarHBondContact O-N 3.44Å; N129-R132 PolarHBondContact OD1-NH2 2.75Å; L130-R132 VanDerWaalsContact C-N 3.33Å; R132-I137 HydrophobicContact CG-CD1 4.26Å; R132-I137 HydrophobicContact CG-CG1 4.5Å
133	T	90.1	Very high	88.1	Confident	65 Å²	65	85.9 Å²	85.9	40%	0.399	42%	0.421	S	S	.	.			trans	-95.2	149.5	177.7	67.7	0	0	0	0	112	K131 R135 R136 I137	K131-T133 PolarHBondContact O-N 2.93Å; T133-R135 PolarHBondContact O-N 3.15Å; T133-R136 PolarHBondContact O-N 2.82Å; T133-R136 VanDerWaalsContact O-N 3.16Å; T133-R136 PolarHBondContact OG1-N 3.09Å; T133-I137 PolarHBondContact O-N 3.07Å; T133-I137 VanDerWaalsContact O-N 3.15Å
134	P	89.4	Confident	88.7	Confident	69 Å²	69	84.1 Å²	84.1	45%	0.448	41%	0.411	S	S	.	.	H	α-helix	trans	-57.1	-34	174.3	-24.4	32.5	0	0	0	113.5	P54 I137 K138	P54-P134 HydrophobicContact CB-CG 4.31Å; P54-P134 HydrophobicContact CG-CG 4.08Å; P134-I137 PolarHBondContact O-N 2.94Å; P134-K138 WeakPolarHBondContact O-CB 3.48Å; P134-K138 WeakPolarHBondContact O-CG 3.27Å; P134-K138 PolarHBondContact O-N 2.96Å
135	R	92.6	Very high	89.4	Confident	222 Å²	222	82.6 Å²	82.6	84%	0.838	40%	0.401	S	S	*	.	H	α-helix	trans	-61.9	-46	177	-68.7	-176.6	-177.9	165.8	0.1	111.3	T133 K138 C139	T133-R135 PolarHBondContact O-N 3.15Å; R135-K138 PolarHBondContact O-N 3.45Å; R135-C139 WeakPolarHBondContact O-CB 3.47Å; R135-C139 PolarHBondContact O-N 2.87Å
136	R	92.2	Very high	90.3	Very high	116 Å²	116	82.9 Å²	82.9	44%	0.438	40%	0.397	S	S	.	.	H	α-helix	trans	-64.2	-42.8	177.6	-171	176.2	-177.9	-174.7	0.5	111.8	T133 C139 I140	T133-R136 PolarHBondContact O-N 2.82Å; T133-R136 VanDerWaalsContact O-N 3.16Å; T133-R136 PolarHBondContact OG1-N 3.09Å; R136-C139 WeakPolarHBondContact O-CB 3.32Å; R136-C139 PolarHBondContact O-N 2.71Å; R136-I140 HydrophobicContact CG-CD1 4.3Å; R136-I140 WeakPolarHBondContact O-CG1 3.42Å; R136-I140 PolarHBondContact O-N 2.98Å
137	I	92.7	Very high	91	Very high	2 Å²	2	79.7 Å²	79.7	1%	0.01	38%	0.381	C	S	.	.	H	α-helix	trans	-62.8	-44.7	177.4	-59.1	-55	0	0	0	111.4	P54 L57 F58 R132 T133 P134 C139 I140 I141	P54-I137 HydrophobicContact CB-CG1 4.12Å; L57-I137 HydrophobicContact CB-CG2 3.97Å; L57-I137 HydrophobicContact CD1-CG2 4.45Å; F58-I137 HydrophobicContact CD1-CG2 4.35Å; F58-I137 HydrophobicContact CD2-CG2 4.19Å; F58-I137 HydrophobicContact CE1-CG2 4.07Å; F58-I137 HydrophobicContact CE2-CD1 3.67Å; F58-I137 HydrophobicContact CE2-CG2 3.93Å; F58-I137 HydrophobicContact CG-CG2 4.39Å; F58-I137 HydrophobicContact CZ-CD1 3.84Å; F58-I137 HydrophobicContact CZ-CG2 3.86Å; R132-I137 HydrophobicContact CG-CD1 4.26Å; R132-I137 HydrophobicContact CG-CG1 4.5Å; T133-I137 PolarHBondContact O-N 3.07Å; T133-I137 VanDerWaalsContact O-N 3.15Å; P134-I137 PolarHBondContact O-N 2.94Å; I137-C139 VanDerWaalsContact C-N 3.3Å; I137-C139 PolarHBondContact O-N 3.14Å; I137-I140 HydrophobicContact CD1-CD1 4.44Å; I137-I140 PolarHBondContact O-N 2.84Å; I137-I141 HydrophobicContact CG2-CD1 3.97Å; I137-I141 HydrophobicContact CG2-CG1 4.49Å; I137-I141 WeakPolarHBondContact O-CG1 3.49Å; I137-I141 PolarHBondContact O-N 3.39Å
138	K	94.5	Very high	91.7	Very high	135 Å²	135	74.7 Å²	74.7	59%	0.587	36%	0.357	S	S	*	.	H	α-helix	trans	-60.3	-39.2	174.7	-72.2	179.8	-178.4	-171.4	0	112.3	L57 P134 R135 I141 F142	L57-K138 HydrophobicContact CD1-CG 4.32Å; P134-K138 WeakPolarHBondContact O-CB 3.48Å; P134-K138 WeakPolarHBondContact O-CG 3.27Å; P134-K138 PolarHBondContact O-N 2.96Å; R135-K138 PolarHBondContact O-N 3.45Å; K138-I141 PolarHBondContact O-N 2.87Å; K138-F142 PolarHBondContact O-N 3.36Å
139	C	95.7	Very high	92.2	Very high	68 Å²	68	75.2 Å²	75.2	46%	0.459	36%	0.363	S	S	.	.	H	α-helix	trans	-63.4	-44.3	174.5	179.8	0	0	0	0	111.9	R135 R136 I137 I141 F142 I143	R135-C139 WeakPolarHBondContact O-CB 3.47Å; R135-C139 PolarHBondContact O-N 2.87Å; R136-C139 WeakPolarHBondContact O-CB 3.32Å; R136-C139 PolarHBondContact O-N 2.71Å; I137-C139 VanDerWaalsContact C-N 3.3Å; I137-C139 PolarHBondContact O-N 3.14Å; C139-I141 PolarHBondContact O-N 3.15Å; C139-F142 WeakPolarHBondContact O-CB 3.37Å; C139-F142 PolarHBondContact O-N 3.31Å; C139-I143 WeakPolarHBondContact O-CG1 3.34Å; C139-I143 PolarHBondContact O-N 2.93Å
140	I	94.9	Very high	92.7	Very high	41 Å²	41	75.6 Å²	75.6	21%	0.21	37%	0.369	C	S	.	.	H	α-helix	trans	-60.8	-46.1	174.8	-64.2	166.1	0	0	0	110.4	F58 A113 R136 I137 F142 I143 V144	F58-I140 HydrophobicContact CE1-CB 4.1Å; F58-I140 HydrophobicContact CE1-CG2 3.68Å; F58-I140 HydrophobicContact CZ-CB 4.18Å; F58-I140 HydrophobicContact CZ-CD1 4.25Å; F58-I140 HydrophobicContact CZ-CG2 3.89Å; A113-I140 HydrophobicContact CB-CG2 4.24Å; R136-I140 HydrophobicContact CG-CD1 4.3Å; R136-I140 WeakPolarHBondContact O-CG1 3.42Å; R136-I140 PolarHBondContact O-N 2.98Å; I137-I140 HydrophobicContact CD1-CD1 4.44Å; I137-I140 PolarHBondContact O-N 2.84Å; I140-F142 VanDerWaalsContact C-N 3.31Å; I140-F142 PolarHBondContact O-N 2.74Å; I140-I143 PolarHBondContact O-N 3.4Å; I140-V144 HydrophobicContact CG2-CG2 4.34Å; I140-V144 WeakPolarHBondContact O-CG2 3.35Å; I140-V144 PolarHBondContact O-N 3.21Å
141	I	97.2	Very high	93.1	Very high	23 Å²	23	70.5 Å²	70.5	12%	0.118	34%	0.342	C	S	.	.	H	α-helix	trans	-56.3	-47.2	176.6	-70.9	165.9	0	0	0	110.7	L57 F58 S61 I137 K138 C139 I143 V144 W145	L57-I141 HydrophobicContact CB-CD1 3.96Å; F58-I141 HydrophobicContact CD1-CD1 4.24Å; F58-I141 HydrophobicContact CD1-CG1 3.71Å; F58-I141 HydrophobicContact CE1-CG1 3.89Å; S61-I141 VanDerWaalsContact OG-CG2 3.29Å; S61-I141 WeakPolarHBondContact OG-CG2 3.14Å; I137-I141 HydrophobicContact CG2-CD1 3.97Å; I137-I141 HydrophobicContact CG2-CG1 4.49Å; I137-I141 WeakPolarHBondContact O-CG1 3.49Å; I137-I141 PolarHBondContact O-N 3.39Å; K138-I141 PolarHBondContact O-N 2.87Å; C139-I141 PolarHBondContact O-N 3.15Å; I141-I143 PolarHBondContact O-N 3.26Å; I141-V144 WeakPolarHBondContact O-CB 3.39Å; I141-V144 PolarHBondContact O-N 3.43Å; I141-W145 VanDerWaalsContact O-CD1 3.23Å; I141-W145 PolarHBondContact O-N 3.37Å
142	F	97.3	Very high	93.4	Very high	138 Å²	138	65.5 Å²	65.5	61%	0.605	32%	0.32	S	S	*	.	H	α-helix	trans	-58.7	-46.5	176.7	177	-99.1	0	0	0	112	K138 C139 I140 V144 W145 V146	K138-F142 PolarHBondContact O-N 3.36Å; C139-F142 WeakPolarHBondContact O-CB 3.37Å; C139-F142 PolarHBondContact O-N 3.31Å; I140-F142 VanDerWaalsContact C-N 3.31Å; I140-F142 PolarHBondContact O-N 2.74Å; F142-V144 VanDerWaalsContact C-N 3.29Å; F142-V144 PolarHBondContact O-N 3.38Å; F142-W145 PolarHBondContact O-N 2.9Å; F142-V146 HydrophobicContact CD1-CG2 4.14Å; F142-V146 HydrophobicContact CE1-CG2 3.7Å; F142-V146 HydrophobicContact CE2-CG2 4.14Å; F142-V146 HydrophobicContact CZ-CG2 3.7Å; F142-V146 WeakPolarHBondContact O-CG2 3.19Å; F142-V146 PolarHBondContact O-N 3.46Å
143	I	96.3	Very high	93.4	Very high	84 Å²	84	67.7 Å²	67.7	43%	0.431	33%	0.332	S	S	.	.	H	α-helix	trans	-58.9	-42.3	176.4	-68.5	164.8	0	0	0	110.9	C139 I140 I141 W145 V146 I147	C139-I143 WeakPolarHBondContact O-CG1 3.34Å; C139-I143 PolarHBondContact O-N 2.93Å; I140-I143 PolarHBondContact O-N 3.4Å; I141-I143 PolarHBondContact O-N 3.26Å; I143-W145 VanDerWaalsContact C-N 3.35Å; I143-W145 PolarHBondContact O-N 3.01Å; I143-V146 PolarHBondContact O-N 2.93Å; I143-I147 HydrophobicContact CG2-CD1 3.68Å; I143-I147 HydrophobicContact CG2-CG1 4.27Å; I143-I147 VanDerWaalsContact O-CG1 3.3Å; I143-I147 WeakPolarHBondContact O-CG1 3.48Å; I143-I147 PolarHBondContact O-N 3.27Å
144	V	96.4	Very high	92.9	Very high	6 Å²	6	66.7 Å²	66.7	4%	0.036	33%	0.326	C	S	.	.	H	α-helix	trans	-59.8	-45.3	177.4	169.5	0	0	0	0	111.4	T109 H110 A113 I140 I141 F142 I147 A148	T109-V144 HydrophobicContact CG2-CB 4.27Å; T109-V144 HydrophobicContact CG2-CG1 3.71Å; T109-V144 HydrophobicContact CG2-CG2 3.97Å; H110-V144 WeakPolarHBondContact CE1-CG1 3.41Å; H110-V144 WeakPolarHBondContact ND1-CG1 3.27Å; A113-V144 HydrophobicContact CB-CG2 4.25Å; I140-V144 HydrophobicContact CG2-CG2 4.34Å; I140-V144 WeakPolarHBondContact O-CG2 3.35Å; I140-V144 PolarHBondContact O-N 3.21Å; I141-V144 WeakPolarHBondContact O-CB 3.39Å; I141-V144 PolarHBondContact O-N 3.43Å; F142-V144 VanDerWaalsContact C-N 3.29Å; F142-V144 PolarHBondContact O-N 3.38Å; V144-I147 PolarHBondContact O-N 2.85Å; V144-A148 WeakPolarHBondContact O-CB 3.5Å; V144-A148 PolarHBondContact O-N 2.79Å
145	W	97.7	Very high	92	Very high	60 Å²	60	64.3 Å²	64.3	23%	0.227	31%	0.311	C	S	.	.	H	α-helix	trans	-64	-40.2	176.1	-80.9	104.2	0	0	0	112.5	S61 A65 L68 L102 F103 A106 H110 I141 F142 I143 A148 A149	S61-W145 PolarHBondContact OG-NE1 3.39Å; A65-W145 HydrophobicContact CB-CH2 4.01Å; A65-W145 HydrophobicContact CB-CZ2 4.14Å; L68-W145 HydrophobicContact CD1-CH2 4.17Å; L102-W145 HydrophobicContact CD2-CZ3 4.43Å; L102-W145 HydrophobicContact CG-CZ3 4.36Å; F103-W145 AromaticContact CD1-CH2 3.87Å; F103-W145 HydrophobicContact CD1-CH2 3.87Å; F103-W145 AromaticContact CD1-CZ3 3.81Å; F103-W145 HydrophobicContact CD1-CZ3 3.81Å; F103-W145 HydrophobicContact CE1-CH2 4.02Å; F103-W145 AromaticContact CE1-CZ3 3.88Å; F103-W145 HydrophobicContact CE1-CZ3 3.88Å; A106-W145 HydrophobicContact CB-CE3 4.24Å; A106-W145 HydrophobicContact CB-CH2 4.29Å; A106-W145 HydrophobicContact CB-CZ3 4.08Å; H110-W145 AromaticContact CE1-NE1 3.61Å; H110-W145 AromaticContact NE2-NE1 3.9Å; I141-W145 VanDerWaalsContact O-CD1 3.23Å; I141-W145 PolarHBondContact O-N 3.37Å; F142-W145 PolarHBondContact O-N 2.9Å; I143-W145 VanDerWaalsContact C-N 3.35Å; I143-W145 PolarHBondContact O-N 3.01Å; W145-A148 PolarHBondContact O-N 3.46Å; W145-A149 VanDerWaalsContact O-CB 3.31Å; W145-A149 WeakPolarHBondContact O-CB 3.22Å; W145-A149 PolarHBondContact O-N 3.02Å
146	V	96.1	Very high	90.9	Very high	63 Å²	63	55.8 Å²	55.8	38%	0.382	28%	0.281	S	S	.	.	H	α-helix	trans	-63.9	-44.4	176	171.6	0	0	0	0	111.3	F142 I143 A148 A149 V150	F142-V146 HydrophobicContact CD1-CG2 4.14Å; F142-V146 HydrophobicContact CE1-CG2 3.7Å; F142-V146 HydrophobicContact CE2-CG2 4.14Å; F142-V146 HydrophobicContact CZ-CG2 3.7Å; F142-V146 WeakPolarHBondContact O-CG2 3.19Å; F142-V146 PolarHBondContact O-N 3.46Å; I143-V146 PolarHBondContact O-N 2.93Å; V146-A148 VanDerWaalsContact C-N 3.33Å; V146-A148 PolarHBondContact O-N 3.36Å; V146-A149 WeakPolarHBondContact O-CB 3.48Å; V146-A149 PolarHBondContact O-N 2.84Å; V146-V150 HydrophobicContact CG1-CG2 4.43Å; V146-V150 VanDerWaalsContact O-CG2 3.3Å; V146-V150 WeakPolarHBondContact O-CG2 3.35Å; V146-V150 PolarHBondContact O-N 2.74Å
147	I	93.6	Very high	89.8	Confident	74 Å²	74	56.5 Å²	56.5	38%	0.379	29%	0.293	S	S	.	.	H	α-helix	trans	-60.5	-46	176.4	-70.2	167.3	0	0	0	110.3	I143 V144 A149 V150 I151	I143-I147 HydrophobicContact CG2-CD1 3.68Å; I143-I147 HydrophobicContact CG2-CG1 4.27Å; I143-I147 VanDerWaalsContact O-CG1 3.3Å; I143-I147 WeakPolarHBondContact O-CG1 3.48Å; I143-I147 PolarHBondContact O-N 3.27Å; V144-I147 PolarHBondContact O-N 2.85Å; I147-A149 VanDerWaalsContact C-N 3.34Å; I147-A149 PolarHBondContact O-N 3.04Å; I147-V150 PolarHBondContact O-N 3.15Å; I147-I151 HydrophobicContact CG2-CD1 3.91Å; I147-I151 WeakPolarHBondContact O-CG1 3.46Å; I147-I151 PolarHBondContact O-N 3.5Å; I147-I151 VanDerWaalsContact O-N 3.17Å
148	A	95.8	Very high	88.4	Confident	0 Å²	0	58.6 Å²	58.6	0%	0	31%	0.305	C	S	.	.	H	α-helix	trans	-60.6	-44.7	178.6	0	0	0	0	0	111.8	L102 T105 A106 V144 W145 V146 I151 S152	L102-A148 HydrophobicContact CD1-CB 3.79Å; T105-A148 HydrophobicContact CG2-CB 3.88Å; A106-A148 HydrophobicContact CB-CB 3.94Å; V144-A148 WeakPolarHBondContact O-CB 3.5Å; V144-A148 PolarHBondContact O-N 2.79Å; W145-A148 PolarHBondContact O-N 3.46Å; V146-A148 VanDerWaalsContact C-N 3.33Å; V146-A148 PolarHBondContact O-N 3.36Å; A148-I151 PolarHBondContact O-N 3.35Å; A148-S152 WeakPolarHBondContact O-CB 3.36Å; A148-S152 PolarHBondContact O-N 3.39Å; A148-S152 PolarHBondContact O-OG 2.94Å; A148-S152 VanDerWaalsContact O-OG 3.12Å
149	A	94.2	Very high	86.6	Confident	20 Å²	20	54.5 Å²	54.5	17%	0.165	29%	0.289	C	S	.	.	H	α-helix	trans	-56.8	-49.9	174.3	0	0	0	0	0	112.7	L102 W145 V146 I147 I151 S152 F153	L102-A149 HydrophobicContact CD1-CB 4.1Å; L102-A149 VanDerWaalsContact CD1-N 3.3Å; W145-A149 VanDerWaalsContact O-CB 3.31Å; W145-A149 WeakPolarHBondContact O-CB 3.22Å; W145-A149 PolarHBondContact O-N 3.02Å; V146-A149 WeakPolarHBondContact O-CB 3.48Å; V146-A149 PolarHBondContact O-N 2.84Å; I147-A149 VanDerWaalsContact C-N 3.34Å; I147-A149 PolarHBondContact O-N 3.04Å; A149-I151 PolarHBondContact O-N 2.98Å; A149-S152 WeakPolarHBondContact CA-OG 3.47Å; A149-S152 PolarHBondContact O-N 2.99Å; A149-S152 VanDerWaalsContact O-N 3.13Å; A149-S152 PolarHBondContact O-OG 3.19Å; A149-S152 VanDerWaalsContact O-OG 3.11Å; A149-F153 VanDerWaalsContact C-CD2 3.44Å; A149-F153 HydrophobicContact CB-CD2 3.66Å; A149-F153 HydrophobicContact CB-CE2 3.36Å; A149-F153 HydrophobicContact CB-CZ 4.47Å; A149-F153 WeakPolarHBondContact O-CB 3.3Å; A149-F153 WeakPolarHBondContact O-CD2 3.43Å; A149-F153 WeakPolarHBondContact O-CG 3.22Å; A149-F153 PolarHBondContact O-N 3.07Å
150	V	91.9	Very high	84.7	Confident	101 Å²	101	54.2 Å²	54.2	61%	0.612	29%	0.292	S	S	*	.	H	α-helix	trans	-60.7	-34.6	-178.9	169.6	0	0	0	0	111.8	V146 I147 P154	V146-V150 HydrophobicContact CG1-CG2 4.43Å; V146-V150 VanDerWaalsContact O-CG2 3.3Å; V146-V150 WeakPolarHBondContact O-CG2 3.35Å; V146-V150 PolarHBondContact O-N 2.74Å; I147-V150 PolarHBondContact O-N 3.15Å; V150-P154 VanDerWaalsContact O-CD 3.31Å; V150-P154 WeakPolarHBondContact O-CD 3.49Å
151	I	89.8	Confident	82.5	Confident	36 Å²	36	60.4 Å²	60.4	19%	0.185	32%	0.317	C	S	.	.	H	α-helix	trans	-76.1	-33.6	177.9	-65.7	167.1	0	0	0	111.6	T105 I147 A148 A149 P154	T105-I151 HydrophobicContact CG2-CB 4.41Å; T105-I151 HydrophobicContact CG2-CD1 3.94Å; T105-I151 HydrophobicContact CG2-CG2 4.49Å; I147-I151 HydrophobicContact CG2-CD1 3.91Å; I147-I151 WeakPolarHBondContact O-CG1 3.46Å; I147-I151 PolarHBondContact O-N 3.5Å; I147-I151 VanDerWaalsContact O-N 3.17Å; A148-I151 PolarHBondContact O-N 3.35Å; A149-I151 PolarHBondContact O-N 2.98Å; I151-P154 WeakPolarHBondContact O-CD 3.34Å
152	S	88.8	Confident	80.4	Confident	0 Å²	0	63.4 Å²	63.4	0%	0	33%	0.334	C	S	.	.	H	α-helix	trans	-88.6	-26.6	-173.8	64.9	0	0	0	0	115.2	A98 A148 A149 P154 P155	A98-S152 WeakPolarHBondContact O-CB 3.22Å; A148-S152 WeakPolarHBondContact O-CB 3.36Å; A148-S152 PolarHBondContact O-N 3.39Å; A148-S152 PolarHBondContact O-OG 2.94Å; A148-S152 VanDerWaalsContact O-OG 3.12Å; A149-S152 WeakPolarHBondContact CA-OG 3.47Å; A149-S152 PolarHBondContact O-N 2.99Å; A149-S152 VanDerWaalsContact O-N 3.13Å; A149-S152 PolarHBondContact O-OG 3.19Å; A149-S152 VanDerWaalsContact O-OG 3.11Å; S152-P154 VanDerWaalsContact C-CD 3.42Å; S152-P155 VanDerWaalsContact O-CD 3.3Å; S152-P155 WeakPolarHBondContact O-CD 2.96Å
153	F	84.2	Confident	78.3	Confident	99 Å²	99	62.2 Å²	62.2	43%	0.434	33%	0.333	S	S	.	.	S	Bend	trans	-77.9	-21	-174.8	-73.7	-53.5	0	0	0	118.1	A149 L156	A149-F153 VanDerWaalsContact C-CD2 3.44Å; A149-F153 HydrophobicContact CB-CD2 3.66Å; A149-F153 HydrophobicContact CB-CE2 3.36Å; A149-F153 HydrophobicContact CB-CZ 4.47Å; A149-F153 WeakPolarHBondContact O-CB 3.3Å; A149-F153 WeakPolarHBondContact O-CD2 3.43Å; A149-F153 WeakPolarHBondContact O-CG 3.22Å; A149-F153 PolarHBondContact O-N 3.07Å; F153-L156 HydrophobicContact CD1-CD1 3.5Å; F153-L156 HydrophobicContact CE1-CD1 3.98Å; F153-L156 WeakPolarHBondContact O-CB 3.28Å; F153-L156 PolarHBondContact O-N 3.2Å; F153-L156 VanDerWaalsContact O-N 3.14Å
154	P	80.3	Confident	76	Confident	43 Å²	43	65.4 Å²	65.4	28%	0.279	35%	0.351	S	S	.	.	H	α-helix	trans	-52.8	-35.4	-178.1	-28.5	35.4	0	0	0	117.2	V150 I151 S152 L156 I157 T158 Y183	V150-P154 VanDerWaalsContact O-CD 3.31Å; V150-P154 WeakPolarHBondContact O-CD 3.49Å; I151-P154 WeakPolarHBondContact O-CD 3.34Å; S152-P154 VanDerWaalsContact C-CD 3.42Å; P154-L156 PolarHBondContact O-N 3.45Å; P154-I157 PolarHBondContact O-N 3.2Å; P154-T158 PolarHBondContact O-N 3.15Å; P154-T158 PolarHBondContact O-OG1 2.86Å; P154-Y183 HydrophobicContact CB-CD2 4.41Å; P154-Y183 HydrophobicContact CB-CE2 4.36Å
155	P	69.1	Low	73.8	Confident	20 Å²	20	71.9 Å²	71.9	13%	0.13	39%	0.386	C	S	.	.	H	α-helix	trans	-63	-37.9	176.8	-25	36.7	0	0	0	114.2	S152 I157 T158 M159 Y183	S152-P155 VanDerWaalsContact O-CD 3.3Å; S152-P155 WeakPolarHBondContact O-CD 2.96Å; P155-I157 PolarHBondContact O-N 3.02Å; P155-T158 PolarHBondContact O-N 3.43Å; P155-M159 PolarHBondContact O-N 3.35Å; P155-Y183 VanDerWaalsContact CD-CE2 3.42Å; P155-Y183 HydrophobicContact CG-CD1 4.28Å; P155-Y183 HydrophobicContact CG-CD2 3.88Å; P155-Y183 HydrophobicContact CG-CE1 3.65Å; P155-Y183 HydrophobicContact CG-CE2 3.23Å; P155-Y183 HydrophobicContact CG-CG 4.36Å; P155-Y183 VanDerWaalsContact CG-OH 3.23Å; P155-Y183 WeakPolarHBondContact CG-OH 3.49Å
156	L	70.8	Confident	71.5	Confident	42 Å²	42	75.1 Å²	75.1	22%	0.22	41%	0.408	C	S	.	.	H	α-helix	trans	-62.9	-25.6	-179.1	-81.6	152.1	0	0	0	112.6	E94 I95 A98 F153 P154	E94-L156 HydrophobicContact CB-CD2 3.58Å; E94-L156 HydrophobicContact CB-CG 4.27Å; I95-L156 HydrophobicContact CG1-CD2 4.04Å; A98-L156 HydrophobicContact CB-CD1 3.31Å; A98-L156 HydrophobicContact CB-CG 4.06Å; F153-L156 HydrophobicContact CD1-CD1 3.5Å; F153-L156 HydrophobicContact CE1-CD1 3.98Å; F153-L156 WeakPolarHBondContact O-CB 3.28Å; F153-L156 PolarHBondContact O-N 3.2Å; F153-L156 VanDerWaalsContact O-N 3.14Å; P154-L156 PolarHBondContact O-N 3.45Å
157	I	69.2	Low	69.1	Low	132 Å²	132	80.9 Å²	80.9	68%	0.677	44%	0.436	S	S	*	.	H	α-helix	trans	-90.7	-31.2	-179.9	-57.7	172.3	0	0	0	111	P154 P155	P154-I157 PolarHBondContact O-N 3.2Å; P155-I157 PolarHBondContact O-N 3.02Å
158	T	62.7	Low	67.2	Low	45 Å²	45	79.7 Å²	79.7	28%	0.276	44%	0.442	S	S	.	.	H	α-helix	trans	-82.2	-33.2	-170.8	-53.4	0	0	0	0	112.4	P154 P155	P154-T158 PolarHBondContact O-N 3.15Å; P154-T158 PolarHBondContact O-OG1 2.86Å; P155-T158 PolarHBondContact O-N 3.43Å
159	M	56.6	Low	65	Low	49 Å²	49	89 Å²	89	24%	0.241	49%	0.486	C	S	.	.	S	Bend	trans	-90.6	-31.8	-172.7	-66.5	-58.2	179.1	0	0	114.1	E94 P155 K161 N162 N178 Q180	E94-M159 VanDerWaalsContact OE1-CB 3.24Å; E94-M159 WeakPolarHBondContact OE1-CB 3.4Å; P155-M159 PolarHBondContact O-N 3.35Å; M159-K161 PolarHBondContact O-N 3.39Å; M159-N162 PolarHBondContact O-N 3.04Å; M159-N178 WeakPolarHBondContact CE-OD1 3.32Å; M159-Q180 VanDerWaalsContact CE-CD 3.5Å; M159-Q180 HydrophobicContact CE-CG 3.84Å
160	A	55.3	Low	63.3	Low	63 Å²	63	97.1 Å²	97.1	52%	0.521	51%	0.512	S	S	.	.	T	Hydrogen-bonded Turn	trans	-56	-16	168.5	0	0	0	0	0	114.1
161	K	50.3	Low	61.8	Low	170 Å²	170	98.3 Å²	98.3	74%	0.739	52%	0.52	S	S	*	.	T	Hydrogen-bonded Turn	trans	-91.8	-18.1	177	-154.6	174.5	-177.1	179.4	0	113.7	M159	M159-K161 PolarHBondContact O-N 3.39Å
162	N	52.6	Low	60.6	Low	87 Å²	87	102.6 Å²	102.6	47%	0.465	54%	0.539	S	S	.	.	T	Hydrogen-bonded Turn	trans	-91.1	-9.5	-178.5	-70.4	-21.1	0	0	0	113.3	M159 N164 D165	M159-N162 PolarHBondContact O-N 3.04Å; N162-N164 PolarHBondContact O-N 2.72Å; N162-D165 PolarHBondContact O-N 3.15Å
163	D	52.2	Low	60	Low	112 Å²	112	104.9 Å²	104.9	60%	0.599	55%	0.553	S	S	*	*	T	Hydrogen-bonded Turn	trans	-70.4	-7.3	177.7	-80.6	-16.1	0	0	0	114.3	D165	D163-D165 PolarHBondContact O-N 3.42Å
164	N	48.7	Very low	59.8	Low	152 Å²	152	105.5 Å²	105.5	81%	0.813	56%	0.558	S	S	*	*	T	Hydrogen-bonded Turn	trans	-77	-4.4	175	-79.4	-12.6	0	0	0	114.1	N162	N162-N164 PolarHBondContact O-N 2.72Å
165	D	50.2	Low	59.9	Low	141 Å²	141	103.7 Å²	103.7	75%	0.754	55%	0.546	S	S	*	.	S	Bend	trans	-127	4.9	-167.5	-108.2	-8.9	0	0	0	117.4	N162 D163	N162-D165 PolarHBondContact O-N 3.15Å; D163-D165 PolarHBondContact O-N 3.42Å
166	N	48.8	Very low	60.6	Low	129 Å²	129	108.7 Å²	108.7	69%	0.69	57%	0.566	S	S	*	*			trans	-140.2	76.7	178.7	-75.4	-57.9	0	0	0	114.6	G168	N166-G168 PolarHBondContact O-N 3.16Å
167	N	46.7	Very low	61.2	Low	183 Å²	183	108.7 Å²	108.7	98%	0.979	57%	0.565	S	S	*	*			trans	-69.1	63.8	159.1	-78.6	-19.5	0	0	0	111.2
168	G	53	Low	61.7	Low	49 Å²	49	103.5 Å²	103.5	51%	0.505	54%	0.539	S	S	.	.			trans	-113.9	111	169	0	0	0	0	0	109	N166 R170	N166-G168 PolarHBondContact O-N 3.16Å; G168-R170 VanDerWaalsContact C-N 3.35Å; G168-R170 PolarHBondContact O-N 3.24Å
169	E	50.8	Low	62.3	Low	196 Å²	196	105.5 Å²	105.5	92%	0.916	55%	0.548	S	S	*	.			trans	-59.7	89.6	178.1	-162.6	171.4	-160	0	0	110.2	T171	E169-T171 PolarHBondContact O-N 3.35Å
170	R	58.1	Low	63.6	Low	191 Å²	191	105.6 Å²	105.6	72%	0.721	55%	0.548	S	S	*	.			trans	-78.1	109.3	174.7	-64.5	-174.8	-165	166.3	7.5	107.8	G168 H172	G168-R170 VanDerWaalsContact C-N 3.35Å; G168-R170 PolarHBondContact O-N 3.24Å; R170-H172 PolarHBondContact O-N 3.3Å
171	T	59.3	Low	65.2	Low	125 Å²	125	108.4 Å²	108.4	77%	0.767	55%	0.549	S	S	*	.	S	Bend	trans	-61.6	-17.1	-178.5	-0.6	0	0	0	0	113.3	E169	E169-T171 PolarHBondContact O-N 3.35Å
172	H	64.4	Low	66.9	Low	127 Å²	127	107.1 Å²	107.1	59%	0.588	54%	0.539	S	S	*	.	S	Bend	trans	-144.9	101.5	170.4	-63.2	-67.2	0	0	0	110.7	R170	R170-H172 PolarHBondContact O-N 3.3Å
173	P	76.8	Confident	68.6	Low	47 Å²	47	103.4 Å²	103.4	31%	0.305	52%	0.519	S	S	.	.			trans	-67.8	136.9	173.4	25.2	-30.7	0	0	0	110.2	W86	W86-P173 WeakPolarHBondContact CB-O 3.47Å; W86-P173 PolarHBondContact N-O 2.91Å; W86-P173 WeakPolarHBondContact O-CG 3.22Å
174	E	79.3	Confident	70.4	Confident	112 Å²	112	98.1 Å²	98.1	52%	0.523	49%	0.49	S	S	.	.			trans	-115.5	130.5	178.6	-66.6	178.4	137.3	0	0	109.7	K176	E174-K176 HydrophobicContact CB-CG 4.34Å; E174-K176 PolarHBondContact O-N 3.45Å; E174-K176 IonicContact OE1-NZ 2.72Å; E174-K176 WeakPolarHBondContact OE2-CE 3.31Å; E174-K176 IonicContact OE2-NZ 2.87Å; E174-K176 PolarHBondContact OE2-NZ 3.48Å
175	C	84.3	Confident	72.4	Confident	6 Å²	6	93.4 Å²	93.4	4%	0.041	47%	0.465	C	S	.	.			trans	-89.4	100.6	173.1	-174.9	0	0	0	0	109.7	N80 W86 C93	N80-C175 PolarHBondContact ND2-O 2.92Å; W86-C175 HydrophobicContact CB-CB 3.8Å; W86-C175 HydrophobicContact CD2-CB 3.33Å; W86-C175 HydrophobicContact CE3-CB 3.47Å; W86-C175 VanDerWaalsContact CE3-CB 3.47Å; W86-C175 HydrophobicContact CG-CB 3.51Å; W86-C175 HydrophobicContact CZ2-CB 4.44Å; W86-C175 HydrophobicContact CZ3-CB 4.09Å; C93-C175 WeakPolarHBondContact CA-SG 3.4Å; C93-C175 HydrophobicContact CB-CB 3.81Å; C93-C175 WeakPolarHBondContact CB-SG 3.4Å; C93-C175 WeakPolarHBondContact SG-CA 3.36Å; C93-C175 WeakPolarHBondContact SG-CB 3.49Å; C93-C175 CovalentContact SG-SG 2.03Å; C93-C175 PolarHBondContact SG-SG 2.94Å
176	K	82.8	Confident	74.4	Confident	124 Å²	124	89.5 Å²	89.5	54%	0.539	45%	0.448	S	S	.	.			trans	-112.1	146.7	179.7	-69.2	-179.7	179.6	164.4	0	110.5	L97 E174	L97-K176 VanDerWaalsContact CD1-O 3.28Å; L97-K176 WeakPolarHBondContact CD1-O 3.38Å; E174-K176 HydrophobicContact CB-CG 4.34Å; E174-K176 PolarHBondContact O-N 3.45Å; E174-K176 IonicContact OE1-NZ 2.72Å; E174-K176 WeakPolarHBondContact OE2-CE 3.31Å; E174-K176 IonicContact OE2-NZ 2.87Å; E174-K176 PolarHBondContact OE2-NZ 3.48Å
177	I	82.9	Confident	76.4	Confident	42 Å²	42	83.7 Å²	83.7	22%	0.215	42%	0.418	C	S	.	.			trans	-58.8	143.9	172.8	-44.7	178.5	0	0	0	108.7	L97 D179 F360 Y364 F380 F384	L97-I177 HydrophobicContact CD2-CG1 4.11Å; I177-D179 PolarHBondContact O-N 3.25Å; I177-F360 HydrophobicContact CD1-CE2 4.35Å; I177-F360 HydrophobicContact CD1-CZ 4.03Å; I177-Y364 HydrophobicContact CG2-CE1 4.28Å; I177-Y364 HydrophobicContact CG2-CE2 4.21Å; I177-Y364 WeakPolarHBondContact CG2-OH 3.09Å; I177-F380 HydrophobicContact CD1-CE1 4.18Å; I177-F380 HydrophobicContact CD1-CZ 4.28Å; I177-F384 HydrophobicContact CD1-CE2 4.36Å
178	N	80.4	Confident	78.6	Confident	23 Å²	23	75 Å²	75	12%	0.123	37%	0.371	C	S	.	.			trans	-57.7	118.5	-176.1	-174.4	24.8	0	0	0	112.7	M159 Q180 Y183 V184 Y364	M159-N178 WeakPolarHBondContact CE-OD1 3.32Å; N178-Q180 VanDerWaalsContact C-N 3.34Å; N178-Q180 PolarHBondContact O-N 2.99Å; N178-Q180 WeakPolarHBondContact OD1-CG 3.45Å; N178-Q180 PolarHBondContact OD1-N 3.46Å; N178-Y183 HydrophobicContact CB-CD1 3.82Å; N178-Y183 HydrophobicContact CB-CE1 4.02Å; N178-Y183 WeakPolarHBondContact ND2-CB 3.47Å; N178-Y183 WeakPolarHBondContact ND2-CD1 3.35Å; N178-Y183 VanDerWaalsContact ND2-CG 3.3Å; N178-V184 WeakPolarHBondContact O-CG2 3.33Å; N178-Y364 PolarHBondContact O-OH 2.86Å
179	D	75.9	Confident	80.6	Confident	87 Å²	87	76.5 Å²	76.5	47%	0.465	37%	0.367	S	S	.	.			trans	-87	2.8	179.8	-74.1	-48	0	0	0	113.4	I177 K181 K367	I177-D179 PolarHBondContact O-N 3.25Å; D179-K181 PolarHBondContact O-N 3.33Å; D179-K181 VanDerWaalsContact O-N 3.12Å; D179-K367 IonicContact OD1-NZ 3.95Å; D179-K367 PolarHBondContact OD1-NZ 2.79Å; D179-K367 IonicContact OD2-NZ 3.53Å
180	Q	83.9	Confident	82.5	Confident	52 Å²	52	68 Å²	68	24%	0.243	33%	0.332	C	S	.	.			trans	-64.7	113.5	177.2	-71.6	-170	-4.9	0	0	112	M159 N178 W182 Y183 V184	M159-Q180 VanDerWaalsContact CE-CD 3.5Å; M159-Q180 HydrophobicContact CE-CG 3.84Å; N178-Q180 VanDerWaalsContact C-N 3.34Å; N178-Q180 PolarHBondContact O-N 2.99Å; N178-Q180 WeakPolarHBondContact OD1-CG 3.45Å; N178-Q180 PolarHBondContact OD1-N 3.46Å; Q180-W182 PolarHBondContact O-N 3.49Å; Q180-Y183 PolarHBondContact O-N 3.21Å; Q180-V184 WeakPolarHBondContact O-CG2 3.46Å; Q180-V184 PolarHBondContact O-N 3.4Å
181	K	87.1	Confident	84.1	Confident	122 Å²	122	59 Å²	59	53%	0.53	30%	0.298	S	S	.	.	H	α-helix	trans	-50.8	-48.8	-171.8	-60.7	-175.2	177.8	179.4	0	114.4	D179 Y183 V184 I185 T368	D179-K181 PolarHBondContact O-N 3.33Å; D179-K181 VanDerWaalsContact O-N 3.12Å; K181-Y183 VanDerWaalsContact C-N 3.3Å; K181-Y183 PolarHBondContact O-N 2.99Å; K181-V184 PolarHBondContact O-N 2.88Å; K181-I185 WeakPolarHBondContact O-CB 3.21Å; K181-I185 WeakPolarHBondContact O-CD1 3.46Å; K181-I185 WeakPolarHBondContact O-CG1 3.5Å; K181-I185 PolarHBondContact O-N 3.35Å; K181-T368 HydrophobicContact CB-CG2 3.82Å; K181-T368 HydrophobicContact CG-CG2 3.81Å
182	W	86.8	Confident	85.7	Confident	142 Å²	142	53 Å²	53	54%	0.538	26%	0.262	S	S	.	.	H	α-helix	trans	-63.1	-38.2	-177.6	73.6	-93	0	0	0	111.9	Q180 S186	Q180-W182 PolarHBondContact O-N 3.49Å; W182-S186 WeakPolarHBondContact O-CB 3.4Å; W182-S186 PolarHBondContact O-N 3.27Å; W182-S186 PolarHBondContact O-OG 2.95Å
183	Y	87.6	Confident	87.2	Confident	9 Å²	9	49.2 Å²	49.2	4%	0.035	24%	0.243	C	C	.	.	H	α-helix	trans	-71.1	-47.5	178.7	170.7	-98.9	0	0	0	110.2	P154 P155 N178 Q180 K181 I185 S186 S187	P154-Y183 HydrophobicContact CB-CD2 4.41Å; P154-Y183 HydrophobicContact CB-CE2 4.36Å; P155-Y183 VanDerWaalsContact CD-CE2 3.42Å; P155-Y183 HydrophobicContact CG-CD1 4.28Å; P155-Y183 HydrophobicContact CG-CD2 3.88Å; P155-Y183 HydrophobicContact CG-CE1 3.65Å; P155-Y183 HydrophobicContact CG-CE2 3.23Å; P155-Y183 HydrophobicContact CG-CG 4.36Å; P155-Y183 VanDerWaalsContact CG-OH 3.23Å; P155-Y183 WeakPolarHBondContact CG-OH 3.49Å; N178-Y183 HydrophobicContact CB-CD1 3.82Å; N178-Y183 HydrophobicContact CB-CE1 4.02Å; N178-Y183 WeakPolarHBondContact ND2-CB 3.47Å; N178-Y183 WeakPolarHBondContact ND2-CD1 3.35Å; N178-Y183 VanDerWaalsContact ND2-CG 3.3Å; Q180-Y183 PolarHBondContact O-N 3.21Å; K181-Y183 VanDerWaalsContact C-N 3.3Å; K181-Y183 PolarHBondContact O-N 2.99Å; Y183-I185 VanDerWaalsContact C-N 3.3Å; Y183-I185 PolarHBondContact O-N 3.18Å; Y183-S186 PolarHBondContact O-N 3.26Å; Y183-S186 PolarHBondContact O-OG 3.26Å; Y183-S186 VanDerWaalsContact O-OG 3.09Å; Y183-S187 WeakPolarHBondContact O-CB 3.3Å; Y183-S187 PolarHBondContact O-N 3.12Å; Y183-S187 PolarHBondContact OH-OG 3.17Å
184	V	89.9	Confident	88	Confident	1 Å²	1	51.5 Å²	51.5	1%	0.006	25%	0.253	C	S	.	.	H	α-helix	trans	-57.5	-46.4	179.1	178.9	0	0	0	0	111	N178 Q180 K181 C188 Y364 T368	N178-V184 WeakPolarHBondContact O-CG2 3.33Å; Q180-V184 WeakPolarHBondContact O-CG2 3.46Å; Q180-V184 PolarHBondContact O-N 3.4Å; K181-V184 PolarHBondContact O-N 2.88Å; V184-C188 WeakPolarHBondContact O-CB 3.41Å; V184-C188 PolarHBondContact O-N 3.43Å; V184-C188 PolarHBondContact O-SG 3.38Å; V184-Y364 HydrophobicContact CB-CE1 4.34Å; V184-Y364 HydrophobicContact CG1-CD1 3.77Å; V184-Y364 HydrophobicContact CG1-CD2 4.14Å; V184-Y364 HydrophobicContact CG1-CE1 3.46Å; V184-Y364 VanDerWaalsContact CG1-CE1 3.46Å; V184-Y364 HydrophobicContact CG1-CE2 3.86Å; V184-Y364 HydrophobicContact CG1-CG 4.09Å; V184-Y364 VanDerWaalsContact CG1-CZ 3.49Å; V184-Y364 HydrophobicContact CG2-CE1 4.29Å; V184-Y364 HydrophobicContact CG2-CE2 4.05Å; V184-Y364 WeakPolarHBondContact CG2-OH 3.42Å; V184-T368 HydrophobicContact CB-CG2 4.01Å; V184-T368 HydrophobicContact CG1-CG2 4.24Å; V184-T368 VanDerWaalsContact CG1-OG1 3.23Å; V184-T368 WeakPolarHBondContact CG1-OG1 3.45Å; V184-T368 HydrophobicContact CG2-CG2 4.5Å
185	I	91.7	Very high	88.6	Confident	54 Å²	54	46.7 Å²	46.7	28%	0.277	23%	0.231	S	C	.	.	H	α-helix	trans	-63	-50.6	179.8	-65.2	163.1	0	0	0	110.6	K181 Y183 S187 I189 T368 L369	K181-I185 WeakPolarHBondContact O-CB 3.21Å; K181-I185 WeakPolarHBondContact O-CD1 3.46Å; K181-I185 WeakPolarHBondContact O-CG1 3.5Å; K181-I185 PolarHBondContact O-N 3.35Å; Y183-I185 VanDerWaalsContact C-N 3.3Å; Y183-I185 PolarHBondContact O-N 3.18Å; I185-S187 PolarHBondContact O-N 3.43Å; I185-I189 HydrophobicContact CG2-CD1 3.69Å; I185-I189 WeakPolarHBondContact O-CB 3.4Å; I185-I189 WeakPolarHBondContact O-CD1 3.22Å; I185-I189 VanDerWaalsContact O-CG1 3.22Å; I185-I189 WeakPolarHBondContact O-CG1 3.41Å; I185-I189 PolarHBondContact O-N 3.37Å; I185-T368 HydrophobicContact CG1-CG2 4.42Å; I185-L369 HydrophobicContact CD1-CD2 3.57Å; I185-L369 HydrophobicContact CG1-CD2 4.02Å
186	S	91.1	Very high	89	Confident	58 Å²	58	47.3 Å²	47.3	41%	0.406	24%	0.235	S	C	.	.	H	α-helix	trans	-65.2	-41.7	-178	62.8	0	0	0	0	112.2	W182 Y183 I189 G190	W182-S186 WeakPolarHBondContact O-CB 3.4Å; W182-S186 PolarHBondContact O-N 3.27Å; W182-S186 PolarHBondContact O-OG 2.95Å; Y183-S186 PolarHBondContact O-N 3.26Å; Y183-S186 PolarHBondContact O-OG 3.26Å; Y183-S186 VanDerWaalsContact O-OG 3.09Å; S186-I189 PolarHBondContact O-N 3.2Å; S186-G190 PolarHBondContact O-N 3.28Å
187	S	91.3	Very high	89.5	Confident	8 Å²	8	45.3 Å²	45.3	6%	0.056	23%	0.233	C	C	.	.	H	α-helix	trans	-64.2	-49	177	-174.1	0	0	0	0	111.4	Y183 I185 I189 G190 S191	Y183-S187 WeakPolarHBondContact O-CB 3.3Å; Y183-S187 PolarHBondContact O-N 3.12Å; Y183-S187 PolarHBondContact OH-OG 3.17Å; I185-S187 PolarHBondContact O-N 3.43Å; S187-I189 VanDerWaalsContact C-N 3.34Å; S187-I189 PolarHBondContact O-N 3.43Å; S187-G190 PolarHBondContact O-N 3.26Å; S187-S191 WeakPolarHBondContact O-CB 3.24Å; S187-S191 PolarHBondContact O-N 3.16Å; S187-S191 PolarHBondContact O-OG 3.11Å
188	C	93.4	Very high	90	Very high	0 Å²	0	46.4 Å²	46.4	0%	0	24%	0.239	C	C	.	.	H	α-helix	trans	-60.2	-41.6	176.7	-73.9	0	0	0	0	112.5	V184 F192 F193 F361 Y364	V184-C188 WeakPolarHBondContact O-CB 3.41Å; V184-C188 PolarHBondContact O-N 3.43Å; V184-C188 PolarHBondContact O-SG 3.38Å; C188-F192 PolarHBondContact O-N 3.45Å; C188-F193 HydrophobicContact CB-CD2 4.26Å; C188-F193 HydrophobicContact CB-CE2 4.15Å; C188-F193 WeakPolarHBondContact O-CD2 3.09Å; C188-F193 PolarHBondContact O-N 2.92Å; C188-F193 VanDerWaalsContact O-N 3.15Å; C188-F361 HydrophobicContact CB-CD1 4.25Å; C188-Y364 WeakPolarHBondContact SG-CD1 3.36Å
189	I	94.3	Very high	90.4	Very high	80 Å²	80	45.5 Å²	45.5	41%	0.41	23%	0.234	S	C	.	.	I	π-helix	trans	-65.6	-50.8	178.1	-69.4	168.7	0	0	0	110.5	I185 S186 S187 F193 L194	I185-I189 HydrophobicContact CG2-CD1 3.69Å; I185-I189 WeakPolarHBondContact O-CB 3.4Å; I185-I189 WeakPolarHBondContact O-CD1 3.22Å; I185-I189 VanDerWaalsContact O-CG1 3.22Å; I185-I189 WeakPolarHBondContact O-CG1 3.41Å; I185-I189 PolarHBondContact O-N 3.37Å; S186-I189 PolarHBondContact O-N 3.2Å; S187-I189 VanDerWaalsContact C-N 3.34Å; S187-I189 PolarHBondContact O-N 3.43Å; I189-F193 PolarHBondContact O-N 3.02Å; I189-L194 HydrophobicContact CG2-CB 4.36Å; I189-L194 WeakPolarHBondContact O-CB 3.19Å; I189-L194 PolarHBondContact O-N 2.96Å
190	G	91.5	Very high	91.1	Very high	17 Å²	17	44.7 Å²	44.7	18%	0.175	23%	0.232	C	C	.	.	I	π-helix	trans	-68.9	-40.8	-176.7	0	0	0	0	0	113.3	S186 S187 P195	S186-G190 PolarHBondContact O-N 3.28Å; S187-G190 PolarHBondContact O-N 3.26Å; G190-P195 WeakPolarHBondContact O-CD 3.11Å; G190-P195 WeakPolarHBondContact O-CG 3.43Å
191	S	91.7	Very high	91.5	Very high	2 Å²	2	47.2 Å²	47.2	1%	0.014	25%	0.246	C	C	.	.	I	π-helix	trans	-79.6	-37.2	-176.7	63.3	0	0	0	0	113	T105 I108 S187 F361	T105-S191 WeakPolarHBondContact OG1-CB 3.45Å; I108-S191 WeakPolarHBondContact CG2-O 3.45Å; S187-S191 WeakPolarHBondContact O-CB 3.24Å; S187-S191 PolarHBondContact O-N 3.16Å; S187-S191 PolarHBondContact O-OG 3.11Å; S191-F361 WeakPolarHBondContact OG-CE1 3.39Å
192	F	93.4	Very high	91.6	Very high	1 Å²	1	42.2 Å²	42.2	0%	0.004	23%	0.226	C	C	.	.	I	π-helix	trans	-123.8	-60.6	-170.9	179.6	-100.8	0	0	0	114	I108 C188 L194 P195 C196 F353 W357 F358 F361	I108-F192 HydrophobicContact CD1-CD2 4Å; I108-F192 WeakPolarHBondContact CD1-O 3.39Å; C188-F192 PolarHBondContact O-N 3.45Å; F192-L194 PolarHBondContact O-N 3.13Å; F192-P195 WeakPolarHBondContact O-CD 3.28Å; F192-C196 WeakPolarHBondContact O-CB 3.27Å; F192-C196 PolarHBondContact O-N 2.63Å; F192-F353 AromaticContact CD2-CE1 3.91Å; F192-F353 HydrophobicContact CD2-CE1 3.91Å; F192-F353 HydrophobicContact CE2-CD1 4.32Å; F192-F353 AromaticContact CE2-CE1 3.83Å; F192-F353 HydrophobicContact CE2-CE1 3.83Å; F192-W357 HydrophobicContact CD2-CB 4.05Å; F192-W357 HydrophobicContact CE2-CB 3.67Å; F192-F358 HydrophobicContact CE1-CB 4.33Å; F192-F358 AromaticContact CE1-CD2 3.98Å; F192-F358 HydrophobicContact CE1-CD2 3.98Å; F192-F358 HydrophobicContact CZ-CB 3.84Å; F192-F358 HydrophobicContact CZ-CD2 4.23Å; F192-F361 HydrophobicContact CB-CB 4.38Å; F192-F361 HydrophobicContact CB-CD1 3.72Å; F192-F361 HydrophobicContact CB-CD2 3.53Å; F192-F361 HydrophobicContact CB-CE1 3.78Å; F192-F361 HydrophobicContact CB-CE2 3.59Å; F192-F361 HydrophobicContact CB-CG 3.6Å; F192-F361 HydrophobicContact CB-CZ 3.72Å; F192-F361 HydrophobicContact CD1-CB 3.71Å; F192-F361 AromaticContact CD1-CD2 3.85Å; F192-F361 HydrophobicContact CD1-CD2 3.85Å; F192-F361 AromaticContact CD1-CG 3.82Å; F192-F361 HydrophobicContact CD1-CG 3.82Å; F192-F361 AromaticContact CD2-CD2 3.39Å; F192-F361 HydrophobicContact CD2-CD2 3.39Å; F192-F361 AromaticContact CD2-CE2 3.61Å; F192-F361 HydrophobicContact CD2-CE2 3.61Å; F192-F361 HydrophobicContact CD2-CG 4.18Å; F192-F361 HydrophobicContact CE1-CB 4.2Å; F192-F361 HydrophobicContact CE1-CD2 4.44Å; F192-F361 HydrophobicContact CE2-CD2 4.05Å; F192-F361 HydrophobicContact CG-CB 4.04Å; F192-F361 HydrophobicContact CG-CD1 4.24Å; F192-F361 AromaticContact CG-CD2 3.29Å; F192-F361 HydrophobicContact CG-CD2 3.29Å; F192-F361 AromaticContact CG-CE2 3.72Å; F192-F361 HydrophobicContact CG-CE2 3.72Å; F192-F361 AromaticContact CG-CG 3.59Å; F192-F361 HydrophobicContact CG-CG 3.59Å; F192-F361 HydrophobicContact CG-CZ 4.36Å
193	F	94.4	Very high	91.6	Very high	46 Å²	46	37.7 Å²	37.7	20%	0.202	21%	0.209	C	C	.	.	I	π-helix	trans	-66.8	-45.3	-167.4	-69.5	-75.9	0	0	0	112.9	C188 I189 C196 V197 F358 F361 M365	C188-F193 HydrophobicContact CB-CD2 4.26Å; C188-F193 HydrophobicContact CB-CE2 4.15Å; C188-F193 WeakPolarHBondContact O-CD2 3.09Å; C188-F193 PolarHBondContact O-N 2.92Å; C188-F193 VanDerWaalsContact O-N 3.15Å; I189-F193 PolarHBondContact O-N 3.02Å; F193-C196 PolarHBondContact O-N 3.26Å; F193-V197 VanDerWaalsContact O-CG2 3.29Å; F193-V197 WeakPolarHBondContact O-CG2 3.37Å; F193-V197 PolarHBondContact O-N 3.27Å; F193-F358 HydrophobicContact CE1-CE2 4.33Å; F193-F361 HydrophobicContact CE2-CB 4.17Å; F193-F361 HydrophobicContact CZ-CB 4.2Å; F193-M365 HydrophobicContact CD2-CE 4.18Å; F193-M365 HydrophobicContact CE1-CE 4.11Å; F193-M365 HydrophobicContact CE2-CE 3.37Å; F193-M365 HydrophobicContact CE2-SD 3.93Å; F193-M365 HydrophobicContact CZ-CE 3.34Å; F193-M365 HydrophobicContact CZ-SD 4.47Å
194	L	93.9	Very high	91.6	Very high	96 Å²	96	40.4 Å²	40.4	50%	0.503	23%	0.227	S	C	.	.	H	α-helix	trans	-65.1	-51.9	-179.8	174.5	68.6	0	0	0	111.9	I189 F192 C196 V197 I198	I189-L194 HydrophobicContact CG2-CB 4.36Å; I189-L194 WeakPolarHBondContact O-CB 3.19Å; I189-L194 PolarHBondContact O-N 2.96Å; F192-L194 PolarHBondContact O-N 3.13Å; L194-C196 VanDerWaalsContact C-N 3.29Å; L194-C196 PolarHBondContact O-N 3.19Å; L194-V197 PolarHBondContact O-N 2.93Å; L194-I198 HydrophobicContact CD1-CD1 4.14Å; L194-I198 HydrophobicContact CD1-CG1 4.47Å; L194-I198 HydrophobicContact CG-CD1 4.12Å; L194-I198 WeakPolarHBondContact O-CG1 3.46Å; L194-I198 PolarHBondContact O-N 3.39Å
195	P	92.6	Very high	91.6	Very high	11 Å²	11	47.6 Å²	47.6	7%	0.071	25%	0.254	C	S	.	.	H	α-helix	trans	-59.8	-38.3	174.8	-22.8	32.6	0	0	0	112.8	I108 G190 F192 I198 M199	I108-P195 HydrophobicContact CD1-CB 3.81Å; I108-P195 HydrophobicContact CG1-CB 3.93Å; I108-P195 HydrophobicContact CG2-CB 4.37Å; I108-P195 HydrophobicContact CG2-CG 4.48Å; G190-P195 WeakPolarHBondContact O-CD 3.11Å; G190-P195 WeakPolarHBondContact O-CG 3.43Å; F192-P195 WeakPolarHBondContact O-CD 3.28Å; P195-I198 PolarHBondContact O-N 3.2Å; P195-M199 WeakPolarHBondContact O-CB 3.37Å; P195-M199 VanDerWaalsContact O-CG 3.25Å; P195-M199 WeakPolarHBondContact O-CG 3.23Å; P195-M199 PolarHBondContact O-N 3.29Å
196	C	92.2	Very high	91.3	Very high	19 Å²	19	45.2 Å²	45.2	13%	0.128	24%	0.242	C	C	.	.	H	α-helix	trans	-61.4	-46.6	177	-177.8	0	0	0	0	111.9	I108 F192 F193 L194 I198 M199 V200	I108-C196 HydrophobicContact CD1-CB 4.23Å; F192-C196 WeakPolarHBondContact O-CB 3.27Å; F192-C196 PolarHBondContact O-N 2.63Å; F193-C196 PolarHBondContact O-N 3.26Å; L194-C196 VanDerWaalsContact C-N 3.29Å; L194-C196 PolarHBondContact O-N 3.19Å; C196-I198 PolarHBondContact O-N 2.89Å; C196-M199 WeakPolarHBondContact O-CB 3.46Å; C196-M199 PolarHBondContact O-N 3.04Å; C196-V200 WeakPolarHBondContact O-CG2 3.42Å; C196-V200 PolarHBondContact O-N 2.76Å
197	V	93.5	Very high	91	Very high	82 Å²	82	48.6 Å²	48.6	50%	0.497	25%	0.246	S	C	.	.	H	α-helix	trans	-60.9	-46.2	176.8	168.9	0	0	0	0	110.7	F193 L194 M199 V200 L201	F193-V197 VanDerWaalsContact O-CG2 3.29Å; F193-V197 WeakPolarHBondContact O-CG2 3.37Å; F193-V197 PolarHBondContact O-N 3.27Å; L194-V197 PolarHBondContact O-N 2.93Å; V197-M199 VanDerWaalsContact C-N 3.31Å; V197-M199 PolarHBondContact O-N 3.26Å; V197-V200 PolarHBondContact O-N 3.29Å; V197-L201 HydrophobicContact CG1-CD1 3.88Å; V197-L201 HydrophobicContact CG1-CG 4.3Å; V197-L201 WeakPolarHBondContact O-CB 3.04Å; V197-L201 VanDerWaalsContact O-CG 3.28Å; V197-L201 WeakPolarHBondContact O-CG 3.11Å; V197-L201 PolarHBondContact O-N 2.92Å
198	I	92.4	Very high	90.7	Very high	64 Å²	64	52.8 Å²	52.8	33%	0.328	27%	0.265	S	S	.	.	H	α-helix	trans	-57.6	-46.8	177.1	-65.9	167	0	0	0	110.2	C112 L194 P195 C196 L201 V202	C112-I198 VanDerWaalsContact SG-CG2 3.56Å; L194-I198 HydrophobicContact CD1-CD1 4.14Å; L194-I198 HydrophobicContact CD1-CG1 4.47Å; L194-I198 HydrophobicContact CG-CD1 4.12Å; L194-I198 WeakPolarHBondContact O-CG1 3.46Å; L194-I198 PolarHBondContact O-N 3.39Å; P195-I198 PolarHBondContact O-N 3.2Å; C196-I198 PolarHBondContact O-N 2.89Å; I198-L201 PolarHBondContact O-N 3Å; I198-V202 HydrophobicContact CG2-CG2 4.28Å; I198-V202 WeakPolarHBondContact O-CB 3.24Å; I198-V202 WeakPolarHBondContact O-CG2 3.29Å; I198-V202 PolarHBondContact O-N 3.07Å
199	M	90.1	Very high	90.3	Very high	4 Å²	4	54.8 Å²	54.8	2%	0.02	28%	0.276	C	S	.	.	H	α-helix	trans	-60.4	-47.3	178.7	-76.5	174.2	65.1	0	0	112.7	I108 L111 C112 P195 C196 V197 L201 V202 Y203 I350	I108-M199 HydrophobicContact CG1-SD 3.93Å; L111-M199 HydrophobicContact CB-CE 3.5Å; L111-M199 HydrophobicContact CB-SD 3.99Å; L111-M199 HydrophobicContact CD1-CE 4.48Å; C112-M199 HydrophobicContact CB-CG 3.63Å; C112-M199 HydrophobicContact CB-SD 3.82Å; C112-M199 PolarHBondContact N-SD 2.88Å; P195-M199 WeakPolarHBondContact O-CB 3.37Å; P195-M199 VanDerWaalsContact O-CG 3.25Å; P195-M199 WeakPolarHBondContact O-CG 3.23Å; P195-M199 PolarHBondContact O-N 3.29Å; C196-M199 WeakPolarHBondContact O-CB 3.46Å; C196-M199 PolarHBondContact O-N 3.04Å; V197-M199 VanDerWaalsContact C-N 3.31Å; V197-M199 PolarHBondContact O-N 3.26Å; M199-L201 PolarHBondContact O-N 3.33Å; M199-V202 PolarHBondContact O-N 3.3Å; M199-Y203 WeakPolarHBondContact O-CB 3.17Å; M199-Y203 PolarHBondContact O-N 3.17Å; M199-I350 HydrophobicContact CE-CB 4.1Å; M199-I350 HydrophobicContact CE-CD1 4.18Å; M199-I350 HydrophobicContact CE-CG1 3.49Å; M199-I350 VanDerWaalsContact CE-CG1 3.49Å; M199-I350 HydrophobicContact CE-CG2 3.83Å
200	V	90.6	Very high	89.5	Confident	70 Å²	70	52.7 Å²	52.7	42%	0.424	27%	0.27	S	S	.	.	H	α-helix	trans	-60.5	-47	178	170.9	0	0	0	0	110.3	C196 V197 V202 Y203 V204	C196-V200 WeakPolarHBondContact O-CG2 3.42Å; C196-V200 PolarHBondContact O-N 2.76Å; V197-V200 PolarHBondContact O-N 3.29Å; V200-V202 PolarHBondContact O-N 3.44Å; V200-Y203 PolarHBondContact O-N 3.21Å; V200-V204 HydrophobicContact CG1-CG2 4.31Å; V200-V204 WeakPolarHBondContact O-CB 3.1Å; V200-V204 VanDerWaalsContact O-CG2 3.28Å; V200-V204 WeakPolarHBondContact O-CG2 3.08Å; V200-V204 PolarHBondContact O-N 3.32Å
201	L	91.7	Very high	89	Confident	105 Å²	105	55.9 Å²	55.9	55%	0.55	28%	0.279	S	S	.	.	H	α-helix	trans	-61	-46.3	178.6	-70.1	175.5	0	0	0	111.9	V197 I198 M199 Y203 V204 R205	V197-L201 HydrophobicContact CG1-CD1 3.88Å; V197-L201 HydrophobicContact CG1-CG 4.3Å; V197-L201 WeakPolarHBondContact O-CB 3.04Å; V197-L201 VanDerWaalsContact O-CG 3.28Å; V197-L201 WeakPolarHBondContact O-CG 3.11Å; V197-L201 PolarHBondContact O-N 2.92Å; I198-L201 PolarHBondContact O-N 3Å; M199-L201 PolarHBondContact O-N 3.33Å; L201-Y203 VanDerWaalsContact C-N 3.3Å; L201-Y203 PolarHBondContact O-N 3.09Å; L201-V204 PolarHBondContact O-N 3.25Å; L201-R205 VanDerWaalsContact O-CG 3.25Å; L201-R205 WeakPolarHBondContact O-CG 3.2Å; L201-R205 PolarHBondContact O-N 3Å
202	V	90.3	Very high	88.5	Confident	17 Å²	17	63.7 Å²	63.7	10%	0.103	31%	0.312	C	S	.	.	H	α-helix	trans	-58.6	-44.9	176.2	170.5	0	0	0	0	110.4	L116 Y119 I198 M199 V200 R205 I206	L116-V202 HydrophobicContact CD2-CG2 3.55Å; L116-V202 HydrophobicContact CG-CG2 4.33Å; Y119-V202 HydrophobicContact CD2-CG1 4.49Å; Y119-V202 HydrophobicContact CG-CG1 4.22Å; I198-V202 HydrophobicContact CG2-CG2 4.28Å; I198-V202 WeakPolarHBondContact O-CB 3.24Å; I198-V202 WeakPolarHBondContact O-CG2 3.29Å; I198-V202 PolarHBondContact O-N 3.07Å; M199-V202 PolarHBondContact O-N 3.3Å; V200-V202 PolarHBondContact O-N 3.44Å; V202-R205 WeakPolarHBondContact O-CB 3.2Å; V202-R205 PolarHBondContact O-N 3.42Å; V202-I206 HydrophobicContact CG1-CD1 3.96Å; V202-I206 HydrophobicContact CG1-CG1 4.44Å; V202-I206 VanDerWaalsContact O-CG1 3.3Å; V202-I206 WeakPolarHBondContact O-CG1 3.33Å; V202-I206 PolarHBondContact O-N 3.38Å
203	Y	85.2	Confident	87.6	Confident	47 Å²	47	69 Å²	69	18%	0.184	33%	0.333	C	S	.	.	H	α-helix	trans	-69.3	-41.3	-178	-164.3	-93.8	0	0	0	112.8	M199 V200 L201 R205 I206 Y207 T343 A347 I350	M199-Y203 WeakPolarHBondContact O-CB 3.17Å; M199-Y203 PolarHBondContact O-N 3.17Å; V200-Y203 PolarHBondContact O-N 3.21Å; L201-Y203 VanDerWaalsContact C-N 3.3Å; L201-Y203 PolarHBondContact O-N 3.09Å; Y203-R205 VanDerWaalsContact C-N 3.27Å; Y203-R205 PolarHBondContact O-N 2.97Å; Y203-I206 PolarHBondContact O-N 2.85Å; Y203-Y207 WeakPolarHBondContact O-CB 3.46Å; Y203-Y207 PolarHBondContact O-N 3.39Å; Y203-T343 HydrophobicContact CE2-CG2 3.88Å; Y203-T343 WeakPolarHBondContact CE2-O 3.41Å; Y203-T343 PolarHBondContact OH-O 3.33Å; Y203-A347 HydrophobicContact CD1-CB 4.49Å; Y203-A347 HydrophobicContact CE1-CB 3.61Å; Y203-A347 HydrophobicContact CE2-CB 3.71Å; Y203-A347 WeakPolarHBondContact OH-CB 3.3Å; Y203-I350 HydrophobicContact CD2-CD1 3.94Å; Y203-I350 HydrophobicContact CG-CD1 4.35Å
204	V	88.3	Confident	86.4	Confident	67 Å²	67	69.7 Å²	69.7	41%	0.406	34%	0.341	S	S	.	.	H	α-helix	trans	-57	-44	172.3	169.5	0	0	0	0	110.2	V200 L201 Y207 Q208	V200-V204 HydrophobicContact CG1-CG2 4.31Å; V200-V204 WeakPolarHBondContact O-CB 3.1Å; V200-V204 VanDerWaalsContact O-CG2 3.28Å; V200-V204 WeakPolarHBondContact O-CG2 3.08Å; V200-V204 PolarHBondContact O-N 3.32Å; L201-V204 PolarHBondContact O-N 3.25Å; V204-Y207 PolarHBondContact O-N 2.93Å; V204-Q208 HydrophobicContact CG1-CG 4.46Å; V204-Q208 WeakPolarHBondContact O-CB 3.32Å; V204-Q208 VanDerWaalsContact O-CG 3.26Å; V204-Q208 WeakPolarHBondContact O-CG 3.43Å; V204-Q208 PolarHBondContact O-N 3.02Å
205	R	89.6	Confident	85.2	Confident	152 Å²	152	74 Å²	74	57%	0.574	35%	0.35	S	S	*	.	H	α-helix	trans	-63.5	-44.5	175.6	-68.3	-66.9	-170.7	171.7	4.9	112.1	Y119 L201 V202 Y203 Y207 Q208 I209	Y119-R205 HydrophobicContact CE2-CB 4.05Å; L201-R205 VanDerWaalsContact O-CG 3.25Å; L201-R205 WeakPolarHBondContact O-CG 3.2Å; L201-R205 PolarHBondContact O-N 3Å; V202-R205 WeakPolarHBondContact O-CB 3.2Å; V202-R205 PolarHBondContact O-N 3.42Å; Y203-R205 VanDerWaalsContact C-N 3.27Å; Y203-R205 PolarHBondContact O-N 2.97Å; R205-Y207 VanDerWaalsContact C-N 3.32Å; R205-Y207 PolarHBondContact O-N 3.32Å; R205-Q208 PolarHBondContact O-N 2.66Å; R205-I209 VanDerWaalsContact O-CG1 3.23Å; R205-I209 WeakPolarHBondContact O-CG1 3.45Å; R205-I209 PolarHBondContact O-N 3.12Å
206	I	85.9	Confident	83.3	Confident	4 Å²	4	76.3 Å²	76.3	2%	0.021	37%	0.371	C	S	.	.	H	α-helix	trans	-58	-46.7	175.3	-67.1	169.5	0	0	0	110.4	R118 Y119 I122 V202 Y203 I209 A210 T343	R118-I206 HydrophobicContact CG-CD1 4.34Å; Y119-I206 HydrophobicContact CD2-CG1 3.8Å; Y119-I206 HydrophobicContact CG-CG1 4.46Å; I122-I206 HydrophobicContact CD1-CG2 3.61Å; V202-I206 HydrophobicContact CG1-CD1 3.96Å; V202-I206 HydrophobicContact CG1-CG1 4.44Å; V202-I206 VanDerWaalsContact O-CG1 3.3Å; V202-I206 WeakPolarHBondContact O-CG1 3.33Å; V202-I206 PolarHBondContact O-N 3.38Å; Y203-I206 PolarHBondContact O-N 2.85Å; I206-I209 PolarHBondContact O-N 3.01Å; I206-A210 WeakPolarHBondContact O-CB 3.46Å; I206-A210 PolarHBondContact O-N 3.07Å; I206-T343 HydrophobicContact CG2-CG2 3.48Å; I206-T343 VanDerWaalsContact CG2-CG2 3.48Å
207	Y	84.5	Confident	81.5	Confident	128 Å²	128	80.5 Å²	80.5	50%	0.502	40%	0.397	S	S	.	.	H	α-helix	trans	-61.6	-46	179.6	176.5	-96.4	0	0	0	111.9	Y203 V204 R205 I209 A210 K211	Y203-Y207 WeakPolarHBondContact O-CB 3.46Å; Y203-Y207 PolarHBondContact O-N 3.39Å; V204-Y207 PolarHBondContact O-N 2.93Å; R205-Y207 VanDerWaalsContact C-N 3.32Å; R205-Y207 PolarHBondContact O-N 3.32Å; Y207-I209 VanDerWaalsContact C-N 3.33Å; Y207-I209 PolarHBondContact O-N 3.38Å; Y207-A210 PolarHBondContact O-N 2.98Å; Y207-K211 HydrophobicContact CE1-CD 4.05Å; Y207-K211 WeakPolarHBondContact O-CB 3.23Å; Y207-K211 PolarHBondContact O-N 2.95Å
208	Q	86.3	Confident	79.6	Confident	96 Å²	96	81 Å²	81	45%	0.449	40%	0.403	S	S	.	.	H	α-helix	trans	-58.2	-44.7	176	-73.5	173.1	-0.8	0	0	111.8	V204 R205 K211 K212	V204-Q208 HydrophobicContact CG1-CG 4.46Å; V204-Q208 WeakPolarHBondContact O-CB 3.32Å; V204-Q208 VanDerWaalsContact O-CG 3.26Å; V204-Q208 WeakPolarHBondContact O-CG 3.43Å; V204-Q208 PolarHBondContact O-N 3.02Å; R205-Q208 PolarHBondContact O-N 2.66Å; Q208-K211 PolarHBondContact O-N 3.05Å; Q208-K212 WeakPolarHBondContact O-CB 3.49Å; Q208-K212 PolarHBondContact O-N 3.43Å
209	I	84.1	Confident	77.7	Confident	43 Å²	43	80.7 Å²	80.7	22%	0.221	42%	0.415	C	S	.	.	H	α-helix	trans	-65.6	-43.3	179.2	-67.2	169.5	0	0	0	110.8	Y119 T123 R205 I206 Y207 K211 K212 R213	Y119-I209 HydrophobicContact CE2-CD1 3.98Å; T123-I209 HydrophobicContact CG2-CD1 3.52Å; R205-I209 VanDerWaalsContact O-CG1 3.23Å; R205-I209 WeakPolarHBondContact O-CG1 3.45Å; R205-I209 PolarHBondContact O-N 3.12Å; I206-I209 PolarHBondContact O-N 3.01Å; Y207-I209 VanDerWaalsContact C-N 3.33Å; Y207-I209 PolarHBondContact O-N 3.38Å; I209-K211 VanDerWaalsContact C-N 3.35Å; I209-K211 PolarHBondContact O-N 3.2Å; I209-K212 PolarHBondContact O-N 3.38Å; I209-R213 WeakPolarHBondContact O-CG 3.36Å; I209-R213 PolarHBondContact O-N 3.3Å
210	A	77.8	Confident	75.6	Confident	35 Å²	35	87.4 Å²	87.4	29%	0.289	45%	0.451	S	S	.	.	H	α-helix	trans	-61	-43.9	175.9	0	0	0	0	0	111.6	I206 Y207 R213 T214	I206-A210 WeakPolarHBondContact O-CB 3.46Å; I206-A210 PolarHBondContact O-N 3.07Å; Y207-A210 PolarHBondContact O-N 2.98Å; A210-R213 PolarHBondContact O-N 3.09Å; A210-T214 PolarHBondContact O-N 2.88Å; A210-T214 VanDerWaalsContact O-N 3.1Å; A210-T214 PolarHBondContact O-OG1 2.98Å
211	K	81.6	Confident	73.4	Confident	84 Å²	84	95.6 Å²	95.6	37%	0.365	47%	0.474	S	S	.	.	H	α-helix	trans	-65.6	-40.2	178.1	-169.3	171.8	-175.1	173.1	0	112.3	Y207 Q208 I209 T214 R215	Y207-K211 HydrophobicContact CE1-CD 4.05Å; Y207-K211 WeakPolarHBondContact O-CB 3.23Å; Y207-K211 PolarHBondContact O-N 2.95Å; Q208-K211 PolarHBondContact O-N 3.05Å; I209-K211 VanDerWaalsContact C-N 3.35Å; I209-K211 PolarHBondContact O-N 3.2Å; K211-T214 WeakPolarHBondContact CA-OG1 3.28Å; K211-T214 PolarHBondContact O-N 3.4Å; K211-T214 PolarHBondContact O-OG1 3.01Å; K211-R215 VanDerWaalsContact CE-NH2 3.33Å; K211-R215 WeakPolarHBondContact O-CG 3.42Å; K211-R215 PolarHBondContact O-N 2.79Å; K211-R215 VanDerWaalsContact O-N 3.14Å
212	K	80.3	Confident	70.6	Confident	166 Å²	166	97.8 Å²	97.8	72%	0.722	48%	0.479	S	S	*	.	H	α-helix	trans	-63.6	-41.1	175.4	-168	173.3	-178	177	0	111.4	Q208 I209 T214 R215 A216	Q208-K212 WeakPolarHBondContact O-CB 3.49Å; Q208-K212 PolarHBondContact O-N 3.43Å; I209-K212 PolarHBondContact O-N 3.38Å; K212-T214 VanDerWaalsContact C-N 3.33Å; K212-T214 PolarHBondContact O-N 3.09Å; K212-R215 PolarHBondContact O-N 2.59Å; K212-A216 PolarHBondContact O-N 3.32Å
213	R	73.5	Confident	68.3	Low	114 Å²	114	102.9 Å²	102.9	43%	0.43	51%	0.513	S	S	.	.	H	α-helix	trans	-67.5	-26.7	175.9	-71.4	180	-176.6	178.5	4.8	113.9	I122 I209 A210	I122-R213 PolarHBondContact O-NH1 3.35Å; I122-R213 PolarHBondContact O-NH2 3.18Å; I209-R213 WeakPolarHBondContact O-CG 3.36Å; I209-R213 PolarHBondContact O-N 3.3Å; A210-R213 PolarHBondContact O-N 3.09Å
214	T	70.4	Confident	66	Low	60 Å²	60	107.2 Å²	107.2	37%	0.368	54%	0.539	S	S	.	.	H	α-helix	trans	-80.8	-24.8	173.6	48.1	0	0	0	0	113.5	A210 K211 K212 Q336 K340	A210-T214 PolarHBondContact O-N 2.88Å; A210-T214 VanDerWaalsContact O-N 3.1Å; A210-T214 PolarHBondContact O-OG1 2.98Å; K211-T214 WeakPolarHBondContact CA-OG1 3.28Å; K211-T214 PolarHBondContact O-N 3.4Å; K211-T214 PolarHBondContact O-OG1 3.01Å; K212-T214 VanDerWaalsContact C-N 3.33Å; K212-T214 PolarHBondContact O-N 3.09Å; T214-Q336 VanDerWaalsContact CG2-NE2 3.33Å; T214-K340 VanDerWaalsContact CG2-CE 3.45Å
215	R	67.9	Low	63.6	Low	185 Å²	185	108.6 Å²	108.6	70%	0.698	56%	0.557	S	S	*	*	H	α-helix	trans	-83.1	-18.6	179.2	-74.8	179.5	173.3	-174.9	-6.7	113.5	K211 K212 P217	K211-R215 VanDerWaalsContact CE-NH2 3.33Å; K211-R215 WeakPolarHBondContact O-CG 3.42Å; K211-R215 PolarHBondContact O-N 2.79Å; K211-R215 VanDerWaalsContact O-N 3.14Å; K212-R215 PolarHBondContact O-N 2.59Å; R215-P217 WeakPolarHBondContact O-CD 3.25Å
216	A	54.1	Low	61.1	Low	61 Å²	61	109 Å²	109	50%	0.504	57%	0.569	S	S	.	*	S	Bend	trans	-96	107.2	171.7	0	0	0	0	0	109.6	K212	K212-A216 PolarHBondContact O-N 3.32Å
217	P	53.5	Low	58.8	Low	106 Å²	106	116.6 Å²	116.6	69%	0.688	61%	0.609	S	S	*	*			trans	-62	145.4	173.2	-16.4	29.7	0	0	0	110.2	R215 G219	R215-P217 WeakPolarHBondContact O-CD 3.25Å; P217-G219 PolarHBondContact O-N 3.46Å
218	P	53.1	Low	56.4	Low	94 Å²	94	119.8 Å²	119.8	61%	0.61	63%	0.625	S	S	*	*	T	Hydrogen-bonded Turn	trans	-73.1	71.8	166.5	31.8	-32.4	0	0	0	108.8	W332	P218-W332 HydrophobicContact CB-CZ2 4.27Å; P218-W332 VanDerWaalsContact CD-CH2 3.47Å; P218-W332 HydrophobicContact CG-CD2 4.21Å; P218-W332 HydrophobicContact CG-CE3 4.13Å; P218-W332 HydrophobicContact CG-CH2 3.62Å; P218-W332 HydrophobicContact CG-CZ2 3.67Å; P218-W332 HydrophobicContact CG-CZ3 3.84Å
219	G	53.9	Low	53.7	Low	57 Å²	57	120.4 Å²	120.4	59%	0.588	64%	0.64	S	S	*	*	T	Hydrogen-bonded Turn	trans	-124.8	-34.3	-178.3	0	0	0	0	0	113.9	P217	P217-G219 PolarHBondContact O-N 3.46Å
220	D	44.2	Very low	51.6	Low	145 Å²	145	124 Å²	124	78%	0.775	67%	0.666	S	S	*	*			trans	-117.5	56.7	-173	-75.3	-43.3	0	0	0	113.5	K222	D220-K222 VanDerWaalsContact C-N 3.29Å; D220-K222 PolarHBondContact O-N 3.17Å
221	R	44.8	Very low	49.4	Very low	241 Å²	241	129.5 Å²	129.5	91%	0.909	69%	0.691	S	S	*	*			trans	-87.4	83.6	146.7	-81.1	-175.8	176	170.6	-3.1	106.7	P223	R221-P223 VanDerWaalsContact O-CD 3.25Å; R221-P223 WeakPolarHBondContact O-CD 3.38Å; R221-P223 VanDerWaalsContact O-N 3.16Å
222	K	34.4	Very low	46.9	Very low	152 Å²	152	131.7 Å²	131.7	66%	0.661	71%	0.712	S	S	*	*			trans	-52.2	119.4	165.6	-72.2	-174.9	178.7	-179.2	0	107.6	D220 N224	D220-K222 VanDerWaalsContact C-N 3.29Å; D220-K222 PolarHBondContact O-N 3.17Å; K222-N224 PolarHBondContact O-N 2.9Å
223	P	41.9	Very low	45	Very low	123 Å²	123	129.6 Å²	129.6	80%	0.799	72%	0.715	S	S	*	*			trans	-74.9	77.6	164.9	26.4	-20.1	0	0	0	107.1	R221 A225	R221-P223 VanDerWaalsContact O-CD 3.25Å; R221-P223 WeakPolarHBondContact O-CD 3.38Å; R221-P223 VanDerWaalsContact O-N 3.16Å; P223-A225 PolarHBondContact O-N 2.87Å
224	N	35.8	Very low	42.9	Very low	139 Å²	139	129 Å²	129	74%	0.743	74%	0.735	S	S	*	*			trans	-89.7	87.6	172.7	-84.6	-1.9	0	0	0	108.9	K222	K222-N224 PolarHBondContact O-N 2.9Å
225	A	37.2	Very low	41.1	Very low	95 Å²	95	131.1 Å²	131.1	79%	0.785	76%	0.758	S	S	*	*			trans	179.7	69.2	140.6	0	0	0	0	0	109.5	P223	P223-A225 PolarHBondContact O-N 2.87Å
226	I	39	Very low	39.2	Very low	160 Å²	160	130.8 Å²	130.8	82%	0.821	77%	0.77	S	S	*	*			trans	-95.2	100	144.6	-62.9	178.6	0	0	0	104.1	K228	I226-K228 PolarHBondContact O-N 2.66Å; I226-K228 VanDerWaalsContact O-N 3.16Å
227	L	37	Very low	38.1	Very low	165 Å²	165	131.6 Å²	131.6	86%	0.864	78%	0.784	S	S	*	*			trans	-62.2	114	169.7	-170.3	72.1	0	0	0	107.1	S229	L227-S229 PolarHBondContact O-N 3.45Å
228	K	33.7	Very low	36.9	Very low	194 Å²	194	136.2 Å²	136.2	84%	0.843	79%	0.793	S	S	*	*	P	Polyproline II helix	trans	-63.3	125.6	163.7	-71.3	176.4	175.7	-179.4	0	107.5	I226	I226-K228 PolarHBondContact O-N 2.66Å; I226-K228 VanDerWaalsContact O-N 3.16Å
229	S	30.6	Very low	35.8	Very low	109 Å²	109	140.7 Å²	140.7	76%	0.762	81%	0.806	S	S	*	*	P	Polyproline II helix	trans	-101.2	139.8	155.9	-168	0	0	0	0	108.5	L227	L227-S229 PolarHBondContact O-N 3.45Å
230	P	39.1	Very low	34.5	Very low	118 Å²	118	146 Å²	146	77%	0.766	82%	0.821	S	S	*	*	P	Polyproline II helix	trans	-79.2	148.4	178.5	-2.4	21	0	0	0	112.4
231	N	31.3	Very low	33.7	Very low	152 Å²	152	142.8 Å²	142.8	81%	0.813	82%	0.823	S	S	*	*	P	Polyproline II helix	trans	-52.4	150.2	163.5	-62.5	-25.1	0	0	0	110.2
232	T	30.2	Very low	32.9	Very low	130 Å²	130	136.7 Å²	136.7	80%	0.798	82%	0.824	S	S	*	*			cis	178.5	-177.1	43.3	-19.6	0	0	0	0	106.7
233	P	38.4	Very low	32.5	Very low	122 Å²	122	133 Å²	133	79%	0.792	83%	0.829	S	S	*	*			cis	-120.2	179.8	-33.3	25.9	-2.9	0	0	0	113
234	A	31.1	Very low	31.7	Very low	102 Å²	102	135.1 Å²	135.1	84%	0.843	83%	0.834	S	S	*	*			trans	-60.9	145.9	-178.9	0	0	0	0	0	116.3
235	A	31.2	Very low	31.4	Very low	104 Å²	104	135.4 Å²	135.4	86%	0.86	84%	0.835	S	S	*	*			trans	-160	145.1	145.3	0	0	0	0	0	111.5
236	N	29.4	Very low	30.9	Very low	178 Å²	178	140.7 Å²	140.7	95%	0.952	84%	0.84	S	S	*	*			trans	-57.5	153.1	-173.9	-80.5	-34.5	0	0	0	116.5
237	G	29.7	Very low	30.3	Very low	77 Å²	77	140.6 Å²	140.6	79%	0.794	84%	0.842	S	S	*	*			trans	174.8	104.2	157.8	0	0	0	0	0	112.9
238	K	29.8	Very low	29.7	Very low	203 Å²	203	143.9 Å²	143.9	88%	0.883	84%	0.843	S	S	*	*			trans	-61.4	143.5	168.6	-71.7	170.3	173	175.8	0	110.3
239	E	29.4	Very low	29.3	Very low	188 Å²	188	142.3 Å²	142.3	88%	0.879	84%	0.842	S	S	*	*				-177.6	155.6	115.9	-103.4	-178.3	141.6	0	0	113.1
240	N	27	Very low	28.9	Very low	168 Å²	168	142.3 Å²	142.3	90%	0.898	84%	0.841	S	S	*	*			trans	-82.4	158.4	-170.8	-56.5	-48.7	0	0	0	112.3
241	G	27.4	Very low	28.1	Very low	79 Å²	79	144.7 Å²	144.7	81%	0.814	84%	0.842	S	S	*	*			trans	172.1	109.2	162.1	0	0	0	0	0	113.9
242	A	26.5	Very low	27.8	Very low	112 Å²	112	143.5 Å²	143.5	93%	0.926	83%	0.831	S	S	*	*			trans	-74.3	159.2	173.3	0	0	0	0	0	112.5
243	G	25.9	Very low	27.5	Very low	75 Å²	75	144.9 Å²	144.9	77%	0.773	83%	0.826	S	S	*	*			trans	147.9	96.8	154.8	0	0	0	0	0	117.5
244	D	26.9	Very low	26.8	Very low	168 Å²	168	145.7 Å²	145.7	90%	0.898	82%	0.823	S	S	*	*				73.6	137.5	128.5	-113.1	0	0	0	0	124.6
245	D	27.7	Very low	26.5	Very low	145 Å²	145	148.3 Å²	148.3	78%	0.775	82%	0.823	S	S	*	*			trans	-57.6	147.8	172.8	-93.4	-48.9	0	0	0	114.8
246	K	28	Very low	26.2	Very low	206 Å²	206	146.5 Å²	146.5	90%	0.896	81%	0.814	S	S	*	*				179.2	137.8	122.7	-101.3	168.3	-176.5	169.9	0	115.2
247	D	25.3	Very low	26	Very low	158 Å²	158	147.3 Å²	147.3	85%	0.845	81%	0.812	S	S	*	*			trans	-50.4	142.4	163.3	-72.2	-49.6	0	0	0	115.3
248	R	26.2	Very low	25.8	Very low	234 Å²	234	152.1 Å²	152.1	88%	0.883	81%	0.814	S	S	*	*			trans	176.9	116.8	135.6	-104.6	174	173.9	-150.3	-1.6	109.7
249	L	23.6	Very low	25.6	Very low	161 Å²	161	147.3 Å²	147.3	84%	0.843	81%	0.813	S	S	*	*				78.2	132.2	84.6	-154.2	79.6	0	0	0	114.3
250	C	22.2	Very low	25.4	Very low	109 Å²	109	145.4 Å²	145.4	74%	0.736	81%	0.807	S	S	*	*			trans	-65.6	174.6	-169.5	-49.5	0	0	0	0	117.4
251	H	24	Very low	25.2	Very low	167 Å²	167	145.4 Å²	145.4	77%	0.773	80%	0.801	S	S	*	*			trans	89.9	132.3	171.4	-85.7	-107.9	0	0	0	115
252	E	23.9	Very low	25.1	Very low	128 Å²	128	149.9 Å²	149.9	60%	0.598	81%	0.806	S	S	*	*			cis	-166.5	150.6	47	-174.6	114.1	154.7	0	0	111.8
253	K	23.2	Very low	25	Very low	158 Å²	158	153.8 Å²	153.8	69%	0.687	81%	0.805	S	S	*	*			trans	18.7	157.7	144.7	-68.1	170.9	-167.9	155.2	0	120.9
254	L	24	Very low	24.9	Very low	140 Å²	140	153.5 Å²	153.5	73%	0.733	80%	0.801	S	S	*	*			cis	-174.1	147	29	-122.9	148.1	0	0	0	106.3
255	N	26.3	Very low	24.8	Very low	156 Å²	156	152.6 Å²	152.6	83%	0.834	80%	0.802	S	S	*	*			trans	164.7	120.5	131.4	-86.5	-4.3	0	0	0	110.2
256	G	23.8	Very low	24.7	Very low	66 Å²	66	149.5 Å²	149.5	68%	0.68	80%	0.804	S	S	*	*			trans	-87.6	155.8	156.7	0	0	0	0	0	109.5
257	E	25.9	Very low	24.5	Very low	195 Å²	195	143 Å²	143	91%	0.911	80%	0.796	S	S	*	*			trans	-160.5	143.6	134.2	-152.3	134.2	108.8	0	0	109
258	Q	24.1	Very low	24.4	Very low	179 Å²	179	143.7 Å²	143.7	84%	0.836	79%	0.794	S	S	*	*			trans	-70.5	147	175.9	-70.7	163	-44.8	0	0	111.1
259	A	26.1	Very low	24.5	Very low	102 Å²	102	144.1 Å²	144.1	84%	0.843	80%	0.795	S	S	*	*			trans	-156.5	116.4	137	0	0	0	0	0	109.5
260	I	24.9	Very low	24.5	Very low	147 Å²	147	145.4 Å²	145.4	75%	0.754	79%	0.794	S	S	*	*			trans	-83.6	159.2	167.8	-74	171.1	0	0	0	107.8
261	E	23.3	Very low	24.8	Very low	168 Å²	168	144.7 Å²	144.7	79%	0.785	80%	0.796	S	S	*	*			trans	83.2	109.6	164.5	-89.5	166.7	-165.9	0	0	118.4
262	L	25.5	Very low	24.8	Very low	173 Å²	173	145.1 Å²	145.1	91%	0.906	80%	0.799	S	S	*	*				-157	133.4	98.7	-126.2	85.4	0	0	0	111.5
263	Q	24.1	Very low	24.9	Very low	195 Å²	195	148 Å²	148	91%	0.911	81%	0.812	S	S	*	*			trans	-83.1	137.7	176.6	-162.1	172.6	29	0	0	109.1
264	G	24.6	Very low	25.1	Very low	68 Å²	68	144.5 Å²	144.5	70%	0.701	81%	0.812	S	S	*	*			trans	-162.5	73.5	-176.1	0	0	0	0	0	115.1
265	V	24.6	Very low	25.3	Very low	149 Å²	149	148.1 Å²	148.1	90%	0.903	82%	0.822	S	S	*	*			trans	56.3	123.8	135.7	-173.3	0	0	0	0	121.1
266	G	25.5	Very low	25.2	Very low	80 Å²	80	143.8 Å²	143.8	83%	0.825	82%	0.815	S	S	*	*			trans	86.2	133.1	141.9	0	0	0	0	0	115.7
267	G	23.9	Very low	25.3	Very low	71 Å²	71	149.6 Å²	149.6	73%	0.732	82%	0.824	S	S	*	*			cis	146	123.1	16.1	0	0	0	0	0	107.8
268	H	23.8	Very low	25.6	Very low	172 Å²	172	147.5 Å²	147.5	80%	0.796	82%	0.817	S	S	*	*			trans	46.9	124	153.1	-88.9	-70.1	0	0	0	123.1
269	R	26.7	Very low	25.8	Very low	242 Å²	242	146.8 Å²	146.8	91%	0.913	82%	0.819	S	S	*	*				177.1	108.2	120.3	-93.9	164.7	-172.5	-173.8	2.9	107.4
270	K	24.8	Very low	25.8	Very low	189 Å²	189	145 Å²	145	82%	0.822	81%	0.811	S	S	*	*				46.5	112.5	76.6	-100.9	-162.2	-179.5	-170.3	0	115.4
271	A	27.2	Very low	26	Very low	94 Å²	94	144.1 Å²	144.1	78%	0.777	81%	0.812	S	S	*	*			trans	163.9	103.9	143.7	0	0	0	0	0	105.8
272	E	24.8	Very low	26.3	Very low	176 Å²	176	144.2 Å²	144.2	82%	0.822	82%	0.818	S	S	*	*				74.8	136.9	58.6	-150.8	166.9	-151.7	0	0	113.7
273	E	26.5	Very low	26.7	Very low	188 Å²	188	143.5 Å²	143.5	88%	0.879	81%	0.814	S	S	*	*			trans	81.3	147.5	172.3	-60.5	-169.9	145	0	0	119.4
274	A	26.9	Very low	27.2	Very low	84 Å²	84	142.6 Å²	142.6	69%	0.694	81%	0.81	S	S	*	*			cis	176.9	166.9	-30.1	0	0	0	0	0	105.7
275	K	28.1	Very low	27.4	Very low	217 Å²	217	147.2 Å²	147.2	94%	0.943	82%	0.819	S	S	*	*			trans	81.4	137.4	173.5	-61.5	178	169.8	178.7	0	115.8
276	G	24	Very low	27.6	Very low	65 Å²	65	145.7 Å²	145.7	67%	0.67	81%	0.814	S	S	*	*			cis	156.2	159.3	7	0	0	0	0	0	108.9
277	E	25.6	Very low	27.6	Very low	187 Å²	187	147 Å²	147	87%	0.874	81%	0.811	S	S	*	*			trans	75.2	107.6	170.3	-61.5	179.2	138.6	0	0	116.8
278	I	32.1	Very low	27.8	Very low	151 Å²	151	148.9 Å²	148.9	77%	0.774	81%	0.813	S	S	*	*				70.2	113.2	61	-52.5	171.9	0	0	0	113.9
279	N	27.9	Very low	27.9	Very low	164 Å²	164	145 Å²	145	88%	0.877	81%	0.805	S	S	*	*			trans	156.4	129.3	146.6	-79.2	-21.9	0	0	0	106.6
280	G	26.5	Very low	28	Very low	65 Å²	65	141 Å²	141	67%	0.67	80%	0.802	S	S	*	*			cis	149.2	124.7	12.3	0	0	0	0	0	106.9
281	V	29.2	Very low	28	Very low	128 Å²	128	140.6 Å²	140.6	78%	0.776	80%	0.803	S	S	*	*			trans	62.2	106.7	151.4	-160.5	0	0	0	0	119	L283	V281-L283 HydrophobicContact CG1-CD1 3.77Å
282	D	30.4	Very low	28	Very low	171 Å²	171	145.2 Å²	145.2	91%	0.914	81%	0.805	S	S	*	*			trans	-75.1	123.4	157.2	-74.4	-48.3	0	0	0	109.3
283	L	33.3	Very low	28	Very low	158 Å²	158	142 Å²	142	83%	0.827	80%	0.797	S	S	*	*			trans	-123.2	133.1	165.6	-125.5	87.3	0	0	0	109.3	V281	V281-L283 HydrophobicContact CG1-CD1 3.77Å
284	E	35.1	Very low	28	Very low	175 Å²	175	140.2 Å²	140.2	82%	0.818	79%	0.794	S	S	*	*			trans	-61	151.1	176.4	-62.1	-168.6	137.9	0	0	112.4
285	D	28	Very low	27.8	Very low	166 Å²	166	143 Å²	143	89%	0.888	80%	0.797	S	S	*	*			trans	-137.3	108	152.4	-104.3	-27.5	0	0	0	110
286	S	29.7	Very low	28.2	Very low	116 Å²	116	138.1 Å²	138.1	81%	0.811	79%	0.787	S	S	*	*			trans	-109.6	119.3	155.1	-69.3	0	0	0	0	107.7
287	S	24.9	Very low	28.1	Very low	107 Å²	107	140.7 Å²	140.7	75%	0.748	79%	0.794	S	S	*	*			trans	-166.9	110.8	159.2	-162	0	0	0	0	107.6
288	S	27.4	Very low	28.2	Very low	112 Å²	112	137.2 Å²	137.2	78%	0.783	79%	0.79	S	S	*	*				55.9	129.6	85.2	-176	0	0	0	0	111.8
289	S	26.7	Very low	28	Very low	90 Å²	90	137.7 Å²	137.7	63%	0.629	79%	0.793	S	S	*	*			cis	-151.8	161.7	16	46.4	0	0	0	0	106.9
290	D	28	Very low	27.9	Very low	158 Å²	158	140.4 Å²	140.4	85%	0.845	79%	0.791	S	S	*	*				-170.3	142.6	95.7	-84.7	-23.1	0	0	0	112.7
291	H	25.8	Very low	28	Very low	181 Å²	181	146.3 Å²	146.3	84%	0.838	80%	0.798	S	S	*	*			trans	-88.3	159.4	176.4	-114.4	-73.5	0	0	0	111.7
292	K	27.2	Very low	27.9	Very low	190 Å²	190	148.6 Å²	148.6	83%	0.826	80%	0.797	S	S	*	*			trans	76	144	156.6	-82.6	-172.7	172.6	175.4	0	117.3
293	V	24.9	Very low	28	Very low	108 Å²	108	146.7 Å²	146.7	66%	0.655	79%	0.792	S	S	*	*			cis	-175.4	154.8	-12.1	122.6	0	0	0	0	106.4
294	N	25.1	Very low	27.8	Very low	152 Å²	152	146.5 Å²	146.5	81%	0.813	79%	0.792	S	S	*	*			trans	74	116.7	160.7	-69.1	-9.4	0	0	0	123.9
295	N	24.6	Very low	27.6	Very low	143 Å²	143	147.6 Å²	147.6	77%	0.765	79%	0.794	S	S	*	*			trans	-40.9	179.7	149.5	-84.3	-18.6	0	0	0	116.3
296	P	36.7	Very low	27.7	Very low	113 Å²	113	143.3 Å²	143.3	73%	0.734	79%	0.789	S	S	*	*			cis	-140.6	-170.4	-47.1	41.2	-22.8	0	0	0	112.6
297	C	21.9	Very low	27.7	Very low	120 Å²	120	147.3 Å²	147.3	81%	0.811	79%	0.792	S	S	*	*			trans	103.5	109.5	150.8	-142.7	0	0	0	0	118.3
298	S	25.8	Very low	28.1	Very low	113 Å²	113	148.4 Å²	148.4	79%	0.79	80%	0.797	S	S	*	*				174.2	123.2	104	48.3	0	0	0	0	111.1
299	I	27.8	Very low	28.4	Very low	162 Å²	162	155 Å²	155	83%	0.831	80%	0.804	S	S	*	*			trans	-78	127.2	166.2	-69.7	170.7	0	0	0	106.9
300	R	26.5	Very low	28.6	Very low	220 Å²	220	158.8 Å²	158.8	83%	0.83	82%	0.817	S	S	*	*			trans	-134.1	93.1	154.4	-142	173.3	178.8	-177.3	1.1	109.3	K302	R300-K302 PolarHBondContact O-N 2.99Å
301	K	28.8	Very low	28.9	Very low	190 Å²	190	156 Å²	156	83%	0.826	81%	0.81	S	S	*	*			trans	-63.7	118.3	158.6	-88.3	179.9	174.6	177.3	0	107.4
302	K	27.8	Very low	29.3	Very low	175 Å²	175	156.5 Å²	156.5	76%	0.761	81%	0.812	S	S	*	*			trans	-115	102.8	150.5	-86.1	-171.9	175.6	-178.1	0	107.5	R300	R300-K302 PolarHBondContact O-N 2.99Å
303	T	31	Very low	29.8	Very low	131 Å²	131	154.8 Å²	154.8	80%	0.804	81%	0.811	S	S	*	*			trans	-55.2	128.6	152.2	25.9	0	0	0	0	108.9
304	N	29.7	Very low	30.2	Very low	154 Å²	154	159.3 Å²	159.3	82%	0.824	82%	0.822	S	S	*	*			trans	-147.6	119.7	150	-118.9	-4.7	0	0	0	113
305	K	31.3	Very low	30.6	Very low	198 Å²	198	158 Å²	158	86%	0.861	82%	0.821	S	S	*	*			trans	-4.3	135.2	155.1	-68	173	173.9	179.7	0	117.7
306	G	30.1	Very low	31.6	Very low	77 Å²	77	154.4 Å²	154.4	79%	0.794	82%	0.818	S	S	*	*			trans	-67.4	159.2	175.5	0	0	0	0	0	114.9
307	K	30.1	Very low	31.3	Very low	199 Å²	199	157 Å²	157	87%	0.865	83%	0.826	S	S	*	*			trans	-138	135.1	152.6	-78.4	-176.7	175.9	179.9	0	107
308	P	33.6	Very low	32.4	Very low	131 Å²	131	156.7 Å²	156.7	85%	0.851	83%	0.825	S	S	*	*			trans	-78.6	128.6	171.7	32.2	-28	0	0	0	107.7
309	R	32.7	Very low	33	Very low	249 Å²	249	158 Å²	158	94%	0.94	82%	0.823	S	S	*	*			trans	-115.1	114.6	162.3	-102.7	-171.7	177.2	178.6	-0.7	108.8	S311	R309-S311 PolarHBondContact O-N 3.47Å
310	L	31.4	Very low	33.3	Very low	171 Å²	171	156.9 Å²	156.9	90%	0.895	82%	0.823	S	S	*	*			trans	-42.5	116.9	168	-162.6	72.3	0	0	0	110.5	Q312	L310-Q312 PolarHBondContact O-N 3.38Å
311	S	34.2	Very low	33.6	Very low	100 Å²	100	154.4 Å²	154.4	70%	0.699	82%	0.822	S	S	*	*			trans	-77.7	110	173.2	52	0	0	0	0	109.5	R309 I313	R309-S311 PolarHBondContact O-N 3.47Å; S311-I313 PolarHBondContact O-N 3.4Å
312	Q	35.1	Very low	34	Very low	190 Å²	190	152.3 Å²	152.3	89%	0.888	81%	0.812	S	S	*	*			trans	-67.9	117.9	157.9	-81.2	-178.8	-25.8	0	0	108.2	L310 K314	L310-Q312 PolarHBondContact O-N 3.38Å; Q312-K314 PolarHBondContact O-N 3.47Å
313	I	37.5	Very low	34.3	Very low	155 Å²	155	153.1 Å²	153.1	80%	0.795	82%	0.819	S	S	*	*			trans	-77.7	115.4	171.5	-64.7	163.5	0	0	0	107	S311	S311-I313 PolarHBondContact O-N 3.4Å
314	K	31.9	Very low	34.9	Very low	202 Å²	202	152 Å²	152	88%	0.878	80%	0.804	S	S	*	*			trans	-89.5	128.8	158.3	-105.8	-177.4	176.1	-177.5	0	107.8	Q312	Q312-K314 PolarHBondContact O-N 3.47Å
315	P	34.9	Very low	35.6	Very low	124 Å²	124	149.4 Å²	149.4	81%	0.805	80%	0.799	S	S	*	*			trans	-83.1	134.2	173.9	32.6	-29.4	0	0	0	109.4
316	G	44.5	Very low	36.4	Very low	68 Å²	68	146.4 Å²	146.4	70%	0.701	79%	0.792	S	S	*	*			trans	115.7	75.2	173.9	0	0	0	0	0	113
317	D	29.9	Very low	37.4	Very low	169 Å²	169	147.3 Å²	147.3	90%	0.904	78%	0.782	S	S	*	*			trans	-154.5	110.5	133.7	-111.9	-22.9	0	0	0	109.7	N319	D317-N319 PolarHBondContact O-N 3.2Å
318	S	45.5	Very low	38.4	Very low	112 Å²	112	145.1 Å²	145.1	78%	0.783	77%	0.773	S	S	*	*			trans	-77.9	91.5	176.9	-51.5	0	0	0	0	108.6
319	N	39.4	Very low	39.4	Very low	142 Å²	142	140.6 Å²	140.6	76%	0.759	75%	0.75	S	S	*	*			trans	178.3	80.4	145.8	-101.2	-38.2	0	0	0	111.3	D317 Q321	D317-N319 PolarHBondContact O-N 3.2Å; N319-Q321 PolarHBondContact O-N 3.04Å
320	V	32.4	Very low	40.6	Very low	137 Å²	137	132.4 Å²	132.4	83%	0.83	73%	0.731	S	S	*	*			trans	-85.9	76.9	151.2	-176.1	0	0	0	0	106.6	K322	V320-K322 PolarHBondContact O-N 3.2Å
321	Q	34	Very low	41.7	Very low	169 Å²	169	134.2 Å²	134.2	79%	0.79	73%	0.725	S	S	*	*			trans	-68.9	95	159.7	-143.4	173.9	20.1	0	0	105.5	N319 Q323	N319-Q321 PolarHBondContact O-N 3.04Å; Q321-Q323 VanDerWaalsContact C-N 3.29Å; Q321-Q323 PolarHBondContact O-N 3.38Å
322	K	36.1	Very low	42.7	Very low	145 Å²	145	135 Å²	135	63%	0.63	71%	0.713	S	S	*	*			trans	-58.3	95.4	176	-151.7	-174.5	-171.4	-152.9	0	107.2	V320 E324	V320-K322 PolarHBondContact O-N 3.2Å; K322-E324 WeakPolarHBondContact CD-OE2 3.4Å; K322-E324 WeakPolarHBondContact CE-OE2 3.29Å; K322-E324 HydrophobicContact CG-CB 4.3Å; K322-E324 IonicContact NZ-OE1 2.75Å; K322-E324 IonicContact NZ-OE2 2.78Å; K322-E324 PolarHBondContact NZ-OE2 3.25Å; K322-E324 PolarHBondContact O-N 2.89Å
323	Q	34.1	Very low	43.6	Very low	193 Å²	193	132.8 Å²	132.8	90%	0.902	70%	0.701	S	S	*	*			trans	-73.5	65	178	-158.1	174.9	12.1	0	0	108.7	Q321	Q321-Q323 VanDerWaalsContact C-N 3.29Å; Q321-Q323 PolarHBondContact O-N 3.38Å
324	E	44.9	Very low	44.6	Very low	106 Å²	106	127.4 Å²	127.4	50%	0.495	68%	0.683	S	S	.	*			trans	-102.4	7.8	-174.1	-132.1	178.1	-170.8	0	0	113.2	K322	K322-E324 WeakPolarHBondContact CD-OE2 3.4Å; K322-E324 WeakPolarHBondContact CE-OE2 3.29Å; K322-E324 HydrophobicContact CG-CB 4.3Å; K322-E324 IonicContact NZ-OE1 2.75Å; K322-E324 IonicContact NZ-OE2 2.78Å; K322-E324 PolarHBondContact NZ-OE2 3.25Å; K322-E324 PolarHBondContact O-N 2.89Å
325	S	44.8	Very low	45.9	Very low	101 Å²	101	125.5 Å²	125.5	71%	0.706	67%	0.671	S	S	*	*	S	Bend	trans	-108.8	-10.5	-164.7	59.5	0	0	0	0	117.7
326	N	47.2	Very low	47	Very low	134 Å²	134	121 Å²	121	72%	0.717	64%	0.639	S	S	*	*	H	α-helix	trans	-103	-15.3	-174.9	-130.2	-2.5	0	0	0	115.8	S330	N326-S330 PolarHBondContact O-N 3.21Å
327	T	51.7	Low	47.8	Very low	97 Å²	97	122.3 Å²	122.3	60%	0.595	63%	0.63	S	S	*	*	H	α-helix	trans	-78.9	-30	178.9	44	0	0	0	0	113.3	S330 R331	T327-S330 PolarHBondContact O-OG 2.86Å; T327-R331 WeakPolarHBondContact O-CB 3.35Å; T327-R331 PolarHBondContact O-N 3.46Å; T327-R331 VanDerWaalsContact O-N 3.07Å
328	K	51	Low	49.2	Very low	153 Å²	153	123.1 Å²	123.1	67%	0.665	62%	0.62	S	S	*	*	H	α-helix	trans	-71.9	-41.4	176.4	-68.7	-179.5	-178.2	171.5	0	111.5	W332	K328-W332 WeakPolarHBondContact O-CB 3.36Å; K328-W332 PolarHBondContact O-N 3.18Å
329	G	54.3	Low	50.1	Low	36 Å²	36	121.9 Å²	121.9	37%	0.371	60%	0.602	S	S	.	*	H	α-helix	trans	-62.5	-46.4	173.8	0	0	0	0	0	112.4	W332 K333	G329-W332 PolarHBondContact O-N 2.94Å; G329-K333 WeakPolarHBondContact O-CB 3.32Å; G329-K333 PolarHBondContact O-N 3.39Å
330	S	57.4	Low	51.3	Low	76 Å²	76	119.9 Å²	119.9	53%	0.531	59%	0.587	S	S	.	*	H	α-helix	trans	-67.3	-38.3	178.8	90.1	0	0	0	0	113	N326 T327 G334	N326-S330 PolarHBondContact O-N 3.21Å; T327-S330 PolarHBondContact O-OG 2.86Å; S330-G334 PolarHBondContact O-N 3.48Å
331	R	54.2	Low	53	Low	209 Å²	209	119 Å²	119	79%	0.789	57%	0.569	S	S	*	*	H	α-helix	trans	-64.3	-39.1	172.8	-91.2	174.9	80.4	162.5	0.8	112.6	T327 R335	T327-R331 WeakPolarHBondContact O-CB 3.35Å; T327-R331 PolarHBondContact O-N 3.46Å; T327-R331 VanDerWaalsContact O-N 3.07Å; R331-R335 WeakPolarHBondContact O-CB 3.5Å; R331-R335 PolarHBondContact O-N 3.24Å
332	W	55.3	Low	54.4	Low	117 Å²	117	115.2 Å²	115.2	44%	0.443	55%	0.55	S	S	.	.	H	α-helix	trans	-69.4	-45.9	178.1	-177	81.5	0	0	0	111.7	P218 K328 G329 G334 R335 Q336	P218-W332 HydrophobicContact CB-CZ2 4.27Å; P218-W332 VanDerWaalsContact CD-CH2 3.47Å; P218-W332 HydrophobicContact CG-CD2 4.21Å; P218-W332 HydrophobicContact CG-CE3 4.13Å; P218-W332 HydrophobicContact CG-CH2 3.62Å; P218-W332 HydrophobicContact CG-CZ2 3.67Å; P218-W332 HydrophobicContact CG-CZ3 3.84Å; K328-W332 WeakPolarHBondContact O-CB 3.36Å; K328-W332 PolarHBondContact O-N 3.18Å; G329-W332 PolarHBondContact O-N 2.94Å; W332-G334 VanDerWaalsContact C-N 3.32Å; W332-G334 PolarHBondContact O-N 2.92Å; W332-R335 PolarHBondContact O-N 3.26Å; W332-Q336 WeakPolarHBondContact O-CB 3.08Å; W332-Q336 PolarHBondContact O-N 3.02Å
333	K	54.9	Low	56	Low	143 Å²	143	109 Å²	109	62%	0.622	52%	0.524	S	S	*	.	H	α-helix	trans	-59.3	-41.7	173.8	-126.6	165.4	-179.5	174.6	0	111.6	G329 Q336 N337	G329-K333 WeakPolarHBondContact O-CB 3.32Å; G329-K333 PolarHBondContact O-N 3.39Å; K333-Q336 PolarHBondContact O-N 3.41Å; K333-N337 WeakPolarHBondContact O-CB 3.3Å; K333-N337 PolarHBondContact O-N 2.8Å
334	G	57.2	Low	58	Low	42 Å²	42	105.4 Å²	105.4	43%	0.433	51%	0.505	S	S	.	.	H	α-helix	trans	-65.8	-39.9	175.9	0	0	0	0	0	113.8	S330 W332 R338	S330-G334 PolarHBondContact O-N 3.48Å; W332-G334 VanDerWaalsContact C-N 3.32Å; W332-G334 PolarHBondContact O-N 2.92Å; G334-R338 PolarHBondContact O-N 3.4Å; G334-R338 VanDerWaalsContact O-N 3.12Å
335	R	59.6	Low	59.4	Low	162 Å²	162	101.1 Å²	101.1	61%	0.611	49%	0.487	S	S	*	.	H	α-helix	trans	-66.5	-40.7	175.6	-169.9	171.3	171.9	155.9	-3	111.4	R331 W332 R338 E339	R331-R335 WeakPolarHBondContact O-CB 3.5Å; R331-R335 PolarHBondContact O-N 3.24Å; W332-R335 PolarHBondContact O-N 3.26Å; R335-R338 PolarHBondContact O-N 3.4Å; R335-E339 IonicContact NE-OE1 2.57Å; R335-E339 WeakPolarHBondContact O-CG 3.04Å; R335-E339 PolarHBondContact O-N 2.9Å; R335-E339 VanDerWaalsContact O-N 3.13Å
336	Q	59.5	Low	60.8	Low	30 Å²	30	97.2 Å²	97.2	14%	0.14	46%	0.457	C	S	.	.	H	α-helix	trans	-67	-40.2	176.6	-162	175.6	20.6	0	0	112.5	T214 W332 K333 R338 E339 K340	T214-Q336 VanDerWaalsContact CG2-NE2 3.33Å; W332-Q336 WeakPolarHBondContact O-CB 3.08Å; W332-Q336 PolarHBondContact O-N 3.02Å; K333-Q336 PolarHBondContact O-N 3.41Å; Q336-R338 VanDerWaalsContact C-N 3.32Å; Q336-R338 PolarHBondContact O-N 3.43Å; Q336-E339 PolarHBondContact O-N 3.12Å; Q336-K340 WeakPolarHBondContact O-CG 3.38Å; Q336-K340 PolarHBondContact O-N 2.92Å
337	N	59.5	Low	62.3	Low	96 Å²	96	92.1 Å²	92.1	51%	0.513	43%	0.434	S	S	.	.	H	α-helix	trans	-65	-34.8	174.6	-81.2	9.1	0	0	0	112.5	K333 R341	K333-N337 WeakPolarHBondContact O-CB 3.3Å; K333-N337 PolarHBondContact O-N 2.8Å; N337-R341 WeakPolarHBondContact O-CB 3.15Å; N337-R341 PolarHBondContact O-N 2.94Å
338	R	60.7	Low	63.9	Low	185 Å²	185	89.3 Å²	89.3	70%	0.698	42%	0.417	S	S	*	.	H	α-helix	trans	-67.2	-37.5	174.5	-156.9	175.8	79	-147.3	6.9	112.2	G334 R335 Q336 F342	G334-R338 PolarHBondContact O-N 3.4Å; G334-R338 VanDerWaalsContact O-N 3.12Å; R335-R338 PolarHBondContact O-N 3.4Å; Q336-R338 VanDerWaalsContact C-N 3.32Å; Q336-R338 PolarHBondContact O-N 3.43Å; R338-F342 PolarHBondContact O-N 3.39Å; R338-F342 VanDerWaalsContact O-N 3.16Å
339	E	63.2	Low	65.3	Low	86 Å²	86	82.3 Å²	82.3	40%	0.402	39%	0.387	S	S	.	.	H	α-helix	trans	-69.6	-40.4	175.6	-72.8	173.6	-167.5	0	0	112.6	R335 Q336 T343	R335-E339 IonicContact NE-OE1 2.57Å; R335-E339 WeakPolarHBondContact O-CG 3.04Å; R335-E339 PolarHBondContact O-N 2.9Å; R335-E339 VanDerWaalsContact O-N 3.13Å; Q336-E339 PolarHBondContact O-N 3.12Å; E339-T343 PolarHBondContact O-N 2.92Å; E339-T343 PolarHBondContact O-OG1 3.4Å
340	K	65.7	Low	66.6	Low	101 Å²	101	81.2 Å²	81.2	44%	0.439	37%	0.372	S	S	.	.	H	α-helix	trans	-62.9	-46.6	172.8	-73.3	177.7	-179.9	178.6	0	111.8	T214 Q336 F342 T343 F344	T214-K340 VanDerWaalsContact CG2-CE 3.45Å; Q336-K340 WeakPolarHBondContact O-CG 3.38Å; Q336-K340 PolarHBondContact O-N 2.92Å; K340-F342 PolarHBondContact O-N 3.05Å; K340-T343 PolarHBondContact O-N 2.74Å; K340-F344 PolarHBondContact O-N 3.36Å
341	R	67.6	Low	68.1	Low	118 Å²	118	79 Å²	79	45%	0.445	36%	0.361	S	S	.	.	H	α-helix	trans	-55.7	-53.5	177.5	-175.2	173.8	173.1	164.8	3.4	110	N337 T343 F344 V345	N337-R341 WeakPolarHBondContact O-CB 3.15Å; N337-R341 PolarHBondContact O-N 2.94Å; R341-T343 VanDerWaalsContact C-N 3.29Å; R341-T343 PolarHBondContact O-N 2.91Å; R341-F344 WeakPolarHBondContact O-CB 3.49Å; R341-F344 PolarHBondContact O-N 2.98Å; R341-F344 VanDerWaalsContact O-N 3.16Å; R341-V345 VanDerWaalsContact O-CG2 3.25Å; R341-V345 WeakPolarHBondContact O-CG2 3.36Å; R341-V345 PolarHBondContact O-N 2.97Å; R341-V345 VanDerWaalsContact O-N 3.1Å
342	F	64.1	Low	69.8	Low	90 Å²	90	70.5 Å²	70.5	40%	0.395	33%	0.333	S	S	.	.	H	α-helix	trans	-59.9	-36.9	-179.1	-171.2	-82.6	0	0	0	113.8	R118 R338 K340 V345 L346	R118-F342 HydrophobicContact CG-CE1 4.24Å; R118-F342 VanDerWaalsContact CZ-CE1 3.41Å; R118-F342 VanDerWaalsContact NH2-CD1 3.29Å; R338-F342 PolarHBondContact O-N 3.39Å; R338-F342 VanDerWaalsContact O-N 3.16Å; K340-F342 PolarHBondContact O-N 3.05Å; F342-V345 WeakPolarHBondContact O-CB 3.46Å; F342-V345 PolarHBondContact O-N 2.72Å; F342-L346 HydrophobicContact CD1-CD1 3.95Å; F342-L346 HydrophobicContact CD1-CG 4.43Å; F342-L346 HydrophobicContact CE1-CD1 3.52Å; F342-L346 HydrophobicContact CE1-CG 4.12Å; F342-L346 HydrophobicContact CZ-CD1 4.45Å; F342-L346 PolarHBondContact O-N 3.33Å
343	T	69.8	Low	71.4	Confident	14 Å²	14	65 Å²	65	9%	0.086	31%	0.312	C	S	.	.	H	α-helix	trans	-66.7	-43.3	177.9	-52.2	0	0	0	0	111	Y203 I206 E339 K340 R341 V345 L346 A347	Y203-T343 HydrophobicContact CE2-CG2 3.88Å; Y203-T343 WeakPolarHBondContact CE2-O 3.41Å; Y203-T343 PolarHBondContact OH-O 3.33Å; I206-T343 HydrophobicContact CG2-CG2 3.48Å; I206-T343 VanDerWaalsContact CG2-CG2 3.48Å; E339-T343 PolarHBondContact O-N 2.92Å; E339-T343 PolarHBondContact O-OG1 3.4Å; K340-T343 PolarHBondContact O-N 2.74Å; R341-T343 VanDerWaalsContact C-N 3.29Å; R341-T343 PolarHBondContact O-N 2.91Å; T343-V345 VanDerWaalsContact C-N 3.3Å; T343-V345 PolarHBondContact O-N 2.78Å; T343-L346 PolarHBondContact O-N 3.23Å; T343-A347 PolarHBondContact O-N 2.97Å
344	F	75.7	Confident	73.2	Confident	117 Å²	117	60 Å²	60	51%	0.513	29%	0.293	S	S	.	.	H	α-helix	trans	-57.5	-41.4	173.9	178.1	-97.4	0	0	0	112.6	K340 R341 L346 A347 V348 F401	K340-F344 PolarHBondContact O-N 3.36Å; R341-F344 WeakPolarHBondContact O-CB 3.49Å; R341-F344 PolarHBondContact O-N 2.98Å; R341-F344 VanDerWaalsContact O-N 3.16Å; F344-L346 VanDerWaalsContact C-N 3.31Å; F344-L346 PolarHBondContact O-N 3.41Å; F344-A347 VanDerWaalsContact O-CB 3.24Å; F344-A347 WeakPolarHBondContact O-CB 3.25Å; F344-A347 PolarHBondContact O-N 3.17Å; F344-A347 VanDerWaalsContact O-N 3.14Å; F344-V348 HydrophobicContact CD1-CG2 4.13Å; F344-V348 HydrophobicContact CE1-CG2 3.7Å; F344-V348 HydrophobicContact CE2-CG2 4.37Å; F344-V348 HydrophobicContact CZ-CG2 3.83Å; F344-V348 WeakPolarHBondContact O-CG2 3.41Å; F344-V348 PolarHBondContact O-N 3.02Å; F344-F401 HydrophobicContact CD1-CE1 4.01Å; F344-F401 AromaticContact CE1-CE1 3.71Å; F344-F401 HydrophobicContact CE1-CE1 3.71Å; F344-F401 HydrophobicContact CE1-CZ 4.01Å
345	V	74.6	Confident	74.9	Confident	17 Å²	17	63.3 Å²	63.3	10%	0.103	30%	0.3	C	S	.	.	H	α-helix	trans	-58.7	-45	177.6	-179.3	0	0	0	0	111.4	R341 F342 T343 V348 V349 I397 F401	R341-V345 VanDerWaalsContact O-CG2 3.25Å; R341-V345 WeakPolarHBondContact O-CG2 3.36Å; R341-V345 PolarHBondContact O-N 2.97Å; R341-V345 VanDerWaalsContact O-N 3.1Å; F342-V345 WeakPolarHBondContact O-CB 3.46Å; F342-V345 PolarHBondContact O-N 2.72Å; T343-V345 VanDerWaalsContact C-N 3.3Å; T343-V345 PolarHBondContact O-N 2.78Å; V345-V348 PolarHBondContact O-N 3.01Å; V345-V349 WeakPolarHBondContact O-CG2 3.22Å; V345-V349 PolarHBondContact O-N 3.23Å; V345-I397 HydrophobicContact CG1-CG2 4.41Å; V345-F401 HydrophobicContact CB-CB 3.98Å; V345-F401 HydrophobicContact CB-CG 4.15Å; V345-F401 HydrophobicContact CG1-CB 3.43Å; V345-F401 VanDerWaalsContact CG1-CB 3.43Å; V345-F401 HydrophobicContact CG1-CD2 4.01Å; V345-F401 HydrophobicContact CG1-CG 3.82Å; V345-F401 HydrophobicContact CG2-CB 3.3Å; V345-F401 HydrophobicContact CG2-CD1 3.67Å; V345-F401 HydrophobicContact CG2-CD2 4.39Å; V345-F401 HydrophobicContact CG2-CG 3.53Å
346	L	73.2	Confident	76.6	Confident	18 Å²	18	55.7 Å²	55.7	9%	0.094	27%	0.271	C	S	.	.	H	α-helix	trans	-65.3	-39.5	177.1	-69.2	173.4	0	0	0	111.5	I114 R118 F342 T343 F344 V348 V349 I350	I114-L346 HydrophobicContact CG2-CD2 3.72Å; R118-L346 HydrophobicContact CB-CD1 3.68Å; R118-L346 HydrophobicContact CG-CD1 3.49Å; R118-L346 VanDerWaalsContact CG-CD1 3.49Å; F342-L346 HydrophobicContact CD1-CD1 3.95Å; F342-L346 HydrophobicContact CD1-CG 4.43Å; F342-L346 HydrophobicContact CE1-CD1 3.52Å; F342-L346 HydrophobicContact CE1-CG 4.12Å; F342-L346 HydrophobicContact CZ-CD1 4.45Å; F342-L346 PolarHBondContact O-N 3.33Å; T343-L346 PolarHBondContact O-N 3.23Å; F344-L346 VanDerWaalsContact C-N 3.31Å; F344-L346 PolarHBondContact O-N 3.41Å; L346-V348 VanDerWaalsContact C-N 3.26Å; L346-V348 PolarHBondContact O-N 3.35Å; L346-V349 PolarHBondContact O-N 3.07Å; L346-I350 WeakPolarHBondContact O-CD1 3.35Å; L346-I350 WeakPolarHBondContact O-CG1 3.37Å; L346-I350 PolarHBondContact O-N 3.17Å
347	A	79.8	Confident	78.3	Confident	27 Å²	27	54.8 Å²	54.8	22%	0.223	27%	0.267	C	S	.	.	H	α-helix	trans	-53.9	-45.7	170.8	0	0	0	0	0	112.2	Y203 T343 F344 I350 G351	Y203-A347 HydrophobicContact CD1-CB 4.49Å; Y203-A347 HydrophobicContact CE1-CB 3.61Å; Y203-A347 HydrophobicContact CE2-CB 3.71Å; Y203-A347 WeakPolarHBondContact OH-CB 3.3Å; T343-A347 PolarHBondContact O-N 2.97Å; F344-A347 VanDerWaalsContact O-CB 3.24Å; F344-A347 WeakPolarHBondContact O-CB 3.25Å; F344-A347 PolarHBondContact O-N 3.17Å; F344-A347 VanDerWaalsContact O-N 3.14Å; A347-I350 PolarHBondContact O-N 3.43Å; A347-G351 PolarHBondContact O-N 3.14Å
348	V	83.7	Confident	80	Confident	39 Å²	39	54.5 Å²	54.5	24%	0.236	26%	0.261	C	S	.	.	H	α-helix	trans	-65	-45.4	-179.1	174.8	0	0	0	0	110.5	F344 V345 L346 I350 G351 V352 I397 F401	F344-V348 HydrophobicContact CD1-CG2 4.13Å; F344-V348 HydrophobicContact CE1-CG2 3.7Å; F344-V348 HydrophobicContact CE2-CG2 4.37Å; F344-V348 HydrophobicContact CZ-CG2 3.83Å; F344-V348 WeakPolarHBondContact O-CG2 3.41Å; F344-V348 PolarHBondContact O-N 3.02Å; V345-V348 PolarHBondContact O-N 3.01Å; L346-V348 VanDerWaalsContact C-N 3.26Å; L346-V348 PolarHBondContact O-N 3.35Å; V348-I350 VanDerWaalsContact C-N 3.3Å; V348-I350 PolarHBondContact O-N 3.49Å; V348-G351 PolarHBondContact O-N 3.39Å; V348-V352 HydrophobicContact CG1-CG2 4.29Å; V348-V352 WeakPolarHBondContact O-CB 3.43Å; V348-V352 VanDerWaalsContact O-CG2 3.29Å; V348-V352 WeakPolarHBondContact O-CG2 3.42Å; V348-V352 PolarHBondContact O-N 3.49Å; V348-I397 HydrophobicContact CG1-CG2 4.49Å; V348-F401 HydrophobicContact CB-CE2 4.18Å; V348-F401 HydrophobicContact CB-CZ 4.41Å; V348-F401 HydrophobicContact CG1-CE2 3.81Å; V348-F401 HydrophobicContact CG1-CZ 4.21Å; V348-F401 HydrophobicContact CG2-CE2 4.38Å; V348-F401 HydrophobicContact CG2-CZ 4.1Å
349	V	81.1	Confident	81.7	Confident	5 Å²	5	47 Å²	47	3%	0.03	24%	0.236	C	C	.	.	H	α-helix	trans	-55.8	-47.2	175	178.2	0	0	0	0	110.9	L111 V345 L346 F353 I397	L111-V349 HydrophobicContact CD1-CG1 4.36Å; L111-V349 HydrophobicContact CD2-CG1 3.43Å; L111-V349 VanDerWaalsContact CD2-CG1 3.43Å; V345-V349 WeakPolarHBondContact O-CG2 3.22Å; V345-V349 PolarHBondContact O-N 3.23Å; L346-V349 PolarHBondContact O-N 3.07Å; V349-F353 PolarHBondContact O-N 3.07Å; V349-F353 VanDerWaalsContact O-N 3.11Å; V349-I397 HydrophobicContact CG2-CB 4.4Å; V349-I397 HydrophobicContact CG2-CD1 4.48Å; V349-I397 HydrophobicContact CG2-CG2 3.45Å; V349-I397 VanDerWaalsContact CG2-CG2 3.45Å
350	I	82.9	Confident	83.2	Confident	14 Å²	14	43.3 Å²	43.3	7%	0.072	22%	0.219	C	C	.	.	H	α-helix	trans	-64.1	-47.3	-179.8	-62.1	167.9	0	0	0	110.9	M199 Y203 L346 A347 V348 V352 F353 V354	M199-I350 HydrophobicContact CE-CB 4.1Å; M199-I350 HydrophobicContact CE-CD1 4.18Å; M199-I350 HydrophobicContact CE-CG1 3.49Å; M199-I350 VanDerWaalsContact CE-CG1 3.49Å; M199-I350 HydrophobicContact CE-CG2 3.83Å; Y203-I350 HydrophobicContact CD2-CD1 3.94Å; Y203-I350 HydrophobicContact CG-CD1 4.35Å; L346-I350 WeakPolarHBondContact O-CD1 3.35Å; L346-I350 WeakPolarHBondContact O-CG1 3.37Å; L346-I350 PolarHBondContact O-N 3.17Å; A347-I350 PolarHBondContact O-N 3.43Å; V348-I350 VanDerWaalsContact C-N 3.3Å; V348-I350 PolarHBondContact O-N 3.49Å; I350-V352 PolarHBondContact O-N 3.19Å; I350-F353 PolarHBondContact O-N 3.47Å; I350-V354 WeakPolarHBondContact O-CG2 3.48Å; I350-V354 PolarHBondContact O-N 3.31Å
351	G	87.8	Confident	84.6	Confident	29 Å²	29	39.1 Å²	39.1	30%	0.299	20%	0.201	S	C	.	.	H	α-helix	trans	-61.4	-42.9	-179.7	0	0	0	0	0	112.2	A347 V348 F353 V354 I355	A347-G351 PolarHBondContact O-N 3.14Å; V348-G351 PolarHBondContact O-N 3.39Å; G351-F353 PolarHBondContact O-N 3.01Å; G351-V354 PolarHBondContact O-N 3.37Å; G351-I355 WeakPolarHBondContact O-CB 3.28Å; G351-I355 WeakPolarHBondContact O-CD1 3.37Å; G351-I355 WeakPolarHBondContact O-CG1 3.23Å; G351-I355 PolarHBondContact O-N 3.34Å
352	V	90.8	Very high	85.8	Confident	31 Å²	31	38 Å²	38	19%	0.188	20%	0.199	C	C	.	.	H	α-helix	trans	-60.4	-46.1	175.3	169.3	0	0	0	0	110.9	V348 I350 V354 I355 C356 L393 I397	V348-V352 HydrophobicContact CG1-CG2 4.29Å; V348-V352 WeakPolarHBondContact O-CB 3.43Å; V348-V352 VanDerWaalsContact O-CG2 3.29Å; V348-V352 WeakPolarHBondContact O-CG2 3.42Å; V348-V352 PolarHBondContact O-N 3.49Å; I350-V352 PolarHBondContact O-N 3.19Å; V352-V354 PolarHBondContact O-N 2.9Å; V352-I355 PolarHBondContact O-N 2.92Å; V352-C356 WeakPolarHBondContact O-CB 3.24Å; V352-C356 PolarHBondContact O-N 3.03Å; V352-C356 PolarHBondContact O-SG 2.88Å; V352-C356 VanDerWaalsContact O-SG 3.33Å; V352-L393 HydrophobicContact CG1-CB 4Å; V352-L393 HydrophobicContact CG1-CD1 3.44Å; V352-L393 VanDerWaalsContact CG1-CD1 3.44Å; V352-L393 HydrophobicContact CG1-CG 4.35Å; V352-I397 HydrophobicContact CB-CD1 4.1Å; V352-I397 HydrophobicContact CG1-CD1 4.14Å; V352-I397 HydrophobicContact CG2-CD1 4.01Å
353	F	88.9	Confident	87.3	Confident	2 Å²	2	34.2 Å²	34.2	1%	0.009	18%	0.183	C	C	.	.	H	α-helix	trans	-57.8	-50	177.9	-173.5	-81	0	0	0	111.9	I108 L111 F192 V349 I350 G351 I355 C356 W357 N390	I108-F353 HydrophobicContact CB-CD1 4.43Å; I108-F353 HydrophobicContact CB-CE1 3.7Å; I108-F353 HydrophobicContact CB-CE2 4.05Å; I108-F353 HydrophobicContact CB-CZ 3.49Å; I108-F353 VanDerWaalsContact CB-CZ 3.49Å; I108-F353 HydrophobicContact CD1-CD1 4.16Å; I108-F353 HydrophobicContact CD1-CE1 3.56Å; I108-F353 HydrophobicContact CD1-CZ 4.23Å; I108-F353 HydrophobicContact CG1-CD1 4.11Å; I108-F353 HydrophobicContact CG1-CE1 3.67Å; I108-F353 HydrophobicContact CG1-CZ 4.03Å; I108-F353 HydrophobicContact CG2-CZ 4.35Å; L111-F353 HydrophobicContact CD1-CB 3.73Å; L111-F353 HydrophobicContact CD1-CD2 3.45Å; L111-F353 VanDerWaalsContact CD1-CD2 3.45Å; L111-F353 HydrophobicContact CD1-CE2 4.31Å; L111-F353 HydrophobicContact CD1-CG 3.65Å; F192-F353 AromaticContact CD2-CE1 3.91Å; F192-F353 HydrophobicContact CD2-CE1 3.91Å; F192-F353 HydrophobicContact CE2-CD1 4.32Å; F192-F353 AromaticContact CE2-CE1 3.83Å; F192-F353 HydrophobicContact CE2-CE1 3.83Å; V349-F353 PolarHBondContact O-N 3.07Å; V349-F353 VanDerWaalsContact O-N 3.11Å; I350-F353 PolarHBondContact O-N 3.47Å; G351-F353 PolarHBondContact O-N 3.01Å; F353-I355 PolarHBondContact O-N 3.45Å; F353-C356 PolarHBondContact O-N 3.44Å; F353-W357 AromaticContact CD2-CD1 3.89Å; F353-W357 HydrophobicContact CE1-CB 3.98Å; F353-W357 AromaticContact CE1-CD1 3.77Å; F353-W357 HydrophobicContact CE1-CG 4.01Å; F353-W357 AromaticContact CE2-CD1 3.45Å; F353-W357 VanDerWaalsContact CE2-CD1 3.45Å; F353-W357 HydrophobicContact CE2-CG 4.33Å; F353-W357 AromaticContact CE2-NE1 3.68Å; F353-W357 HydrophobicContact CZ-CB 4.25Å; F353-W357 AromaticContact CZ-CD1 3.34Å; F353-W357 AromaticContact CZ-CG 3.79Å; F353-W357 HydrophobicContact CZ-CG 3.79Å; F353-W357 AromaticContact CZ-NE1 3.83Å; F353-W357 PolarHBondContact O-N 2.9Å; F353-N390 WeakPolarHBondContact CA-OD1 3.34Å; F353-N390 WeakPolarHBondContact CD2-ND2 3.34Å
354	V	91.7	Very high	88.3	Confident	38 Å²	38	34.1 Å²	34.1	23%	0.23	18%	0.182	C	C	.	.	H	α-helix	trans	-62.6	-44.5	-179.7	175.2	0	0	0	0	110.7	I350 G351 V352 C356 W357 F358	I350-V354 WeakPolarHBondContact O-CG2 3.48Å; I350-V354 PolarHBondContact O-N 3.31Å; G351-V354 PolarHBondContact O-N 3.37Å; V352-V354 PolarHBondContact O-N 2.9Å; V354-C356 VanDerWaalsContact C-N 3.33Å; V354-C356 PolarHBondContact O-N 3.47Å; V354-W357 PolarHBondContact O-N 3.19Å; V354-F358 HydrophobicContact CG1-CB 4.17Å; V354-F358 WeakPolarHBondContact O-CA 3.34Å; V354-F358 WeakPolarHBondContact O-CB 3.21Å; V354-F358 PolarHBondContact O-N 2.87Å
355	I	93.8	Very high	89.1	Confident	110 Å²	110	30.5 Å²	30.5	56%	0.564	17%	0.167	S	C	*	.	H	α-helix	trans	-60.8	-43.8	179.1	-71.1	164.9	0	0	0	110.9	G351 V352 F353 P359 F386	G351-I355 WeakPolarHBondContact O-CB 3.28Å; G351-I355 WeakPolarHBondContact O-CD1 3.37Å; G351-I355 WeakPolarHBondContact O-CG1 3.23Å; G351-I355 PolarHBondContact O-N 3.34Å; V352-I355 PolarHBondContact O-N 2.92Å; F353-I355 PolarHBondContact O-N 3.45Å; I355-P359 WeakPolarHBondContact O-CD 3.49Å; I355-F386 HydrophobicContact CG2-CE1 4.25Å; I355-F386 HydrophobicContact CG2-CZ 4.26Å; I355-F386 VanDerWaalsContact O-CE1 3.31Å; I355-F386 WeakPolarHBondContact O-CE1 3.13Å
356	C	94.4	Very high	89.9	Confident	3 Å²	3	32.2 Å²	32.2	2%	0.02	18%	0.175	C	C	.	.	H	α-helix	trans	-67.6	-43	-179.6	-70.9	0	0	0	0	113.2	V352 F353 V354 F386 N390	V352-C356 WeakPolarHBondContact O-CB 3.24Å; V352-C356 PolarHBondContact O-N 3.03Å; V352-C356 PolarHBondContact O-SG 2.88Å; V352-C356 VanDerWaalsContact O-SG 3.33Å; F353-C356 PolarHBondContact O-N 3.44Å; V354-C356 VanDerWaalsContact C-N 3.33Å; V354-C356 PolarHBondContact O-N 3.47Å; C356-F386 HydrophobicContact CB-CE1 4.48Å; C356-F386 WeakPolarHBondContact O-CD1 3.16Å; C356-N390 HydrophobicContact CB-CB 3.85Å
357	W	94.6	Very high	90.6	Very high	10 Å²	10	36.2 Å²	36.2	4%	0.038	19%	0.192	C	C	.	.	H	α-helix	trans	-98.4	-28.3	-169.9	-78.5	100.4	0	0	0	114.8	C104 F192 F353 V354 P359 F360 F361 G387	C104-W357 HydrophobicContact CB-CH2 3.97Å; C104-W357 HydrophobicContact CB-CZ2 4.2Å; C104-W357 HydrophobicContact CB-CZ3 4.41Å; C104-W357 VanDerWaalsContact SG-CH2 3.55Å; C104-W357 VanDerWaalsContact SG-CZ3 3.57Å; F192-W357 HydrophobicContact CD2-CB 4.05Å; F192-W357 HydrophobicContact CE2-CB 3.67Å; F353-W357 AromaticContact CD2-CD1 3.89Å; F353-W357 HydrophobicContact CE1-CB 3.98Å; F353-W357 AromaticContact CE1-CD1 3.77Å; F353-W357 HydrophobicContact CE1-CG 4.01Å; F353-W357 AromaticContact CE2-CD1 3.45Å; F353-W357 VanDerWaalsContact CE2-CD1 3.45Å; F353-W357 HydrophobicContact CE2-CG 4.33Å; F353-W357 AromaticContact CE2-NE1 3.68Å; F353-W357 HydrophobicContact CZ-CB 4.25Å; F353-W357 AromaticContact CZ-CD1 3.34Å; F353-W357 AromaticContact CZ-CG 3.79Å; F353-W357 HydrophobicContact CZ-CG 3.79Å; F353-W357 AromaticContact CZ-NE1 3.83Å; F353-W357 PolarHBondContact O-N 2.9Å; V354-W357 PolarHBondContact O-N 3.19Å; W357-P359 VanDerWaalsContact C-CD 3.46Å; W357-F360 HydrophobicContact CE3-CD1 4.12Å; W357-F360 HydrophobicContact CZ3-CD1 4.09Å; W357-F360 PolarHBondContact O-N 3.45Å; W357-F361 HydrophobicContact CB-CD2 4.03Å; W357-F361 HydrophobicContact CB-CE2 4.07Å; W357-F361 HydrophobicContact CD2-CE2 4.08Å; W357-F361 HydrophobicContact CE3-CD2 4.1Å; W357-F361 AromaticContact CE3-CE2 3.46Å; W357-F361 HydrophobicContact CE3-CE2 3.46Å; W357-F361 VanDerWaalsContact CE3-CE2 3.46Å; W357-F361 HydrophobicContact CE3-CZ 4.25Å; W357-F361 HydrophobicContact CG-CE2 4.37Å; W357-F361 HydrophobicContact CZ3-CE2 4.22Å; W357-F361 WeakPolarHBondContact O-CD2 3.31Å; W357-F361 PolarHBondContact O-N 3.49Å; W357-F361 VanDerWaalsContact O-N 3.11Å; W357-G387 PolarHBondContact NE1-O 3.11Å
358	F	95.5	Very high	91.1	Very high	91 Å²	91	35.5 Å²	35.5	40%	0.399	19%	0.185	S	C	.	.	H	α-helix	trans	-54.3	-45.6	-178.9	177.8	-95.1	0	0	0	113.5	F192 F193 V354 F360 F361 F362	F192-F358 HydrophobicContact CE1-CB 4.33Å; F192-F358 AromaticContact CE1-CD2 3.98Å; F192-F358 HydrophobicContact CE1-CD2 3.98Å; F192-F358 HydrophobicContact CZ-CB 3.84Å; F192-F358 HydrophobicContact CZ-CD2 4.23Å; F193-F358 HydrophobicContact CE1-CE2 4.33Å; V354-F358 HydrophobicContact CG1-CB 4.17Å; V354-F358 WeakPolarHBondContact O-CA 3.34Å; V354-F358 WeakPolarHBondContact O-CB 3.21Å; V354-F358 PolarHBondContact O-N 2.87Å; F358-F360 VanDerWaalsContact C-N 3.28Å; F358-F360 PolarHBondContact O-N 3.48Å; F358-F361 PolarHBondContact O-N 3.47Å; F358-F362 HydrophobicContact CD1-CB 4.49Å; F358-F362 HydrophobicContact CE1-CB 4.17Å; F358-F362 HydrophobicContact CE1-CG 4.34Å; F358-F362 HydrophobicContact CZ-CB 4.18Å; F358-F362 HydrophobicContact CZ-CD2 4.07Å; F358-F362 HydrophobicContact CZ-CG 4.25Å; F358-F362 WeakPolarHBondContact O-CB 3.12Å; F358-F362 PolarHBondContact O-N 2.87Å
359	P	96.4	Very high	91.3	Very high	26 Å²	26	38.8 Å²	38.8	17%	0.169	20%	0.2	C	C	.	.	H	α-helix	trans	-59.3	-39.4	-178.8	-24	35.1	0	0	0	112.8	I355 W357 T363 F383	I355-P359 WeakPolarHBondContact O-CD 3.49Å; W357-P359 VanDerWaalsContact C-CD 3.46Å; P359-T363 WeakPolarHBondContact O-CB 3.31Å; P359-T363 WeakPolarHBondContact O-CG2 3.44Å; P359-T363 PolarHBondContact O-N 2.99Å; P359-T363 PolarHBondContact O-OG1 2.9Å; P359-F383 HydrophobicContact CB-CB 4.14Å; P359-F383 HydrophobicContact CB-CD1 3.41Å; P359-F383 VanDerWaalsContact CB-CD1 3.41Å; P359-F383 HydrophobicContact CB-CD2 3.92Å; P359-F383 HydrophobicContact CB-CE1 3.65Å; P359-F383 HydrophobicContact CB-CE2 4.12Å; P359-F383 HydrophobicContact CB-CG 3.56Å; P359-F383 HydrophobicContact CB-CZ 3.99Å; P359-F383 HydrophobicContact CG-CD1 4.34Å; P359-F383 HydrophobicContact CG-CE1 4.45Å
360	F	95	Very high	91.6	Very high	10 Å²	10	40.2 Å²	40.2	4%	0.044	21%	0.21	C	C	.	.	H	α-helix	trans	-67.8	-54.7	177.5	173.4	-105.1	0	0	0	111.5	I177 W357 F358 F362 T363 Y364 F380 F383 F384	I177-F360 HydrophobicContact CD1-CE2 4.35Å; I177-F360 HydrophobicContact CD1-CZ 4.03Å; W357-F360 HydrophobicContact CE3-CD1 4.12Å; W357-F360 HydrophobicContact CZ3-CD1 4.09Å; W357-F360 PolarHBondContact O-N 3.45Å; F358-F360 VanDerWaalsContact C-N 3.28Å; F358-F360 PolarHBondContact O-N 3.48Å; F360-F362 VanDerWaalsContact C-N 3.27Å; F360-F362 PolarHBondContact O-N 2.9Å; F360-T363 PolarHBondContact O-N 3.32Å; F360-T363 PolarHBondContact O-OG1 3.28Å; F360-T363 VanDerWaalsContact O-OG1 3.07Å; F360-Y364 HydrophobicContact CZ-CD1 4.41Å; F360-Y364 VanDerWaalsContact O-CB 3.28Å; F360-Y364 WeakPolarHBondContact O-CB 3.37Å; F360-Y364 PolarHBondContact O-N 3.47Å; F360-F380 HydrophobicContact CD2-CE2 4.29Å; F360-F380 HydrophobicContact CD2-CZ 4.29Å; F360-F380 HydrophobicContact CE2-CE1 4.02Å; F360-F380 AromaticContact CE2-CE2 3.92Å; F360-F380 HydrophobicContact CE2-CE2 3.92Å; F360-F380 AromaticContact CE2-CZ 3.51Å; F360-F380 HydrophobicContact CE2-CZ 3.51Å; F360-F380 HydrophobicContact CZ-CZ 4.26Å; F360-F383 HydrophobicContact CB-CB 4.13Å; F360-F384 HydrophobicContact CD2-CB 3.86Å; F360-F384 AromaticContact CD2-CD2 3.95Å; F360-F384 HydrophobicContact CD2-CD2 3.95Å; F360-F384 HydrophobicContact CD2-CG 4.44Å; F360-F384 HydrophobicContact CE1-CD2 4.31Å; F360-F384 HydrophobicContact CE2-CB 3.97Å; F360-F384 AromaticContact CE2-CD2 3.45Å; F360-F384 HydrophobicContact CE2-CD2 3.45Å; F360-F384 VanDerWaalsContact CE2-CD2 3.45Å; F360-F384 HydrophobicContact CE2-CE2 4.36Å; F360-F384 HydrophobicContact CE2-CG 4.17Å; F360-F384 AromaticContact CZ-CD2 3.65Å; F360-F384 HydrophobicContact CZ-CD2 3.65Å; F360-F384 HydrophobicContact CZ-CE2 4.16Å
361	F	94.6	Very high	91.5	Very high	12 Å²	12	46.8 Å²	46.8	5%	0.053	24%	0.244	C	C	.	.	H	α-helix	trans	-62.3	-35.8	-178.7	-78.6	-73.7	0	0	0	112.6	C188 S191 F192 F193 W357 F358 M365	C188-F361 HydrophobicContact CB-CD1 4.25Å; S191-F361 WeakPolarHBondContact OG-CE1 3.39Å; F192-F361 HydrophobicContact CB-CB 4.38Å; F192-F361 HydrophobicContact CB-CD1 3.72Å; F192-F361 HydrophobicContact CB-CD2 3.53Å; F192-F361 HydrophobicContact CB-CE1 3.78Å; F192-F361 HydrophobicContact CB-CE2 3.59Å; F192-F361 HydrophobicContact CB-CG 3.6Å; F192-F361 HydrophobicContact CB-CZ 3.72Å; F192-F361 HydrophobicContact CD1-CB 3.71Å; F192-F361 AromaticContact CD1-CD2 3.85Å; F192-F361 HydrophobicContact CD1-CD2 3.85Å; F192-F361 AromaticContact CD1-CG 3.82Å; F192-F361 HydrophobicContact CD1-CG 3.82Å; F192-F361 AromaticContact CD2-CD2 3.39Å; F192-F361 HydrophobicContact CD2-CD2 3.39Å; F192-F361 AromaticContact CD2-CE2 3.61Å; F192-F361 HydrophobicContact CD2-CE2 3.61Å; F192-F361 HydrophobicContact CD2-CG 4.18Å; F192-F361 HydrophobicContact CE1-CB 4.2Å; F192-F361 HydrophobicContact CE1-CD2 4.44Å; F192-F361 HydrophobicContact CE2-CD2 4.05Å; F192-F361 HydrophobicContact CG-CB 4.04Å; F192-F361 HydrophobicContact CG-CD1 4.24Å; F192-F361 AromaticContact CG-CD2 3.29Å; F192-F361 HydrophobicContact CG-CD2 3.29Å; F192-F361 AromaticContact CG-CE2 3.72Å; F192-F361 HydrophobicContact CG-CE2 3.72Å; F192-F361 AromaticContact CG-CG 3.59Å; F192-F361 HydrophobicContact CG-CG 3.59Å; F192-F361 HydrophobicContact CG-CZ 4.36Å; F193-F361 HydrophobicContact CE2-CB 4.17Å; F193-F361 HydrophobicContact CZ-CB 4.2Å; W357-F361 HydrophobicContact CB-CD2 4.03Å; W357-F361 HydrophobicContact CB-CE2 4.07Å; W357-F361 HydrophobicContact CD2-CE2 4.08Å; W357-F361 HydrophobicContact CE3-CD2 4.1Å; W357-F361 AromaticContact CE3-CE2 3.46Å; W357-F361 HydrophobicContact CE3-CE2 3.46Å; W357-F361 VanDerWaalsContact CE3-CE2 3.46Å; W357-F361 HydrophobicContact CE3-CZ 4.25Å; W357-F361 HydrophobicContact CG-CE2 4.37Å; W357-F361 HydrophobicContact CZ3-CE2 4.22Å; W357-F361 WeakPolarHBondContact O-CD2 3.31Å; W357-F361 PolarHBondContact O-N 3.49Å; W357-F361 VanDerWaalsContact O-N 3.11Å; F358-F361 PolarHBondContact O-N 3.47Å; F361-M365 VanDerWaalsContact O-CB 3.3Å; F361-M365 WeakPolarHBondContact O-CB 3.44Å; F361-M365 PolarHBondContact O-N 3.3Å
362	F	94.6	Very high	91.3	Very high	96 Å²	96	51 Å²	51	42%	0.421	27%	0.269	S	S	.	.	H	α-helix	trans	-65.2	-51.1	174.8	179.7	-99.4	0	0	0	111.7	F358 F360 Y364 M365 L366	F358-F362 HydrophobicContact CD1-CB 4.49Å; F358-F362 HydrophobicContact CE1-CB 4.17Å; F358-F362 HydrophobicContact CE1-CG 4.34Å; F358-F362 HydrophobicContact CZ-CB 4.18Å; F358-F362 HydrophobicContact CZ-CD2 4.07Å; F358-F362 HydrophobicContact CZ-CG 4.25Å; F358-F362 WeakPolarHBondContact O-CB 3.12Å; F358-F362 PolarHBondContact O-N 2.87Å; F360-F362 VanDerWaalsContact C-N 3.27Å; F360-F362 PolarHBondContact O-N 2.9Å; F362-Y364 VanDerWaalsContact C-N 3.32Å; F362-Y364 PolarHBondContact O-N 3.42Å; F362-M365 PolarHBondContact O-N 2.78Å; F362-L366 HydrophobicContact CE1-CD2 4.28Å; F362-L366 WeakPolarHBondContact O-CB 3.13Å; F362-L366 PolarHBondContact O-N 3.46Å
363	T	93.9	Very high	91.2	Very high	10 Å²	10	51.8 Å²	51.8	6%	0.061	28%	0.275	C	S	.	.	H	α-helix	trans	-66.9	-33.5	179.8	50.2	0	0	0	0	112.8	P359 F360 L366 K367 V375 F383	P359-T363 WeakPolarHBondContact O-CB 3.31Å; P359-T363 WeakPolarHBondContact O-CG2 3.44Å; P359-T363 PolarHBondContact O-N 2.99Å; P359-T363 PolarHBondContact O-OG1 2.9Å; F360-T363 PolarHBondContact O-N 3.32Å; F360-T363 PolarHBondContact O-OG1 3.28Å; F360-T363 VanDerWaalsContact O-OG1 3.07Å; T363-L366 PolarHBondContact O-N 3.03Å; T363-K367 WeakPolarHBondContact O-CB 3.01Å; T363-K367 PolarHBondContact O-N 3.49Å; T363-V375 HydrophobicContact CG2-CG1 4.28Å; T363-F383 HydrophobicContact CG2-CD2 3.69Å; T363-F383 HydrophobicContact CG2-CE2 3.69Å
364	Y	92.4	Very high	91	Very high	12 Å²	12	59.2 Å²	59.2	5%	0.047	32%	0.315	C	S	.	.	H	α-helix	trans	-65.4	-47	174.8	-171.9	-146.6	0	0	0	111.5	I177 N178 V184 C188 F360 F362 L366 K367 T368 F380	I177-Y364 HydrophobicContact CG2-CE1 4.28Å; I177-Y364 HydrophobicContact CG2-CE2 4.21Å; I177-Y364 WeakPolarHBondContact CG2-OH 3.09Å; N178-Y364 PolarHBondContact O-OH 2.86Å; V184-Y364 HydrophobicContact CB-CE1 4.34Å; V184-Y364 HydrophobicContact CG1-CD1 3.77Å; V184-Y364 HydrophobicContact CG1-CD2 4.14Å; V184-Y364 HydrophobicContact CG1-CE1 3.46Å; V184-Y364 VanDerWaalsContact CG1-CE1 3.46Å; V184-Y364 HydrophobicContact CG1-CE2 3.86Å; V184-Y364 HydrophobicContact CG1-CG 4.09Å; V184-Y364 VanDerWaalsContact CG1-CZ 3.49Å; V184-Y364 HydrophobicContact CG2-CE1 4.29Å; V184-Y364 HydrophobicContact CG2-CE2 4.05Å; V184-Y364 WeakPolarHBondContact CG2-OH 3.42Å; C188-Y364 WeakPolarHBondContact SG-CD1 3.36Å; F360-Y364 HydrophobicContact CZ-CD1 4.41Å; F360-Y364 VanDerWaalsContact O-CB 3.28Å; F360-Y364 WeakPolarHBondContact O-CB 3.37Å; F360-Y364 PolarHBondContact O-N 3.47Å; F362-Y364 VanDerWaalsContact C-N 3.32Å; F362-Y364 PolarHBondContact O-N 3.42Å; Y364-L366 VanDerWaalsContact C-N 3.32Å; Y364-L366 PolarHBondContact O-N 2.91Å; Y364-K367 PolarHBondContact O-N 2.91Å; Y364-T368 PolarHBondContact O-N 3.02Å; Y364-T368 PolarHBondContact O-OG1 3.12Å; Y364-T368 VanDerWaalsContact O-OG1 3.09Å; Y364-F380 HydrophobicContact CD2-CE2 4.12Å; Y364-F380 AromaticContact CD2-CZ 3.94Å; Y364-F380 HydrophobicContact CD2-CZ 3.94Å; Y364-F380 HydrophobicContact CG-CE2 4.38Å; Y364-F380 HydrophobicContact CG-CZ 4.38Å
365	M	92.3	Very high	90.8	Very high	41 Å²	41	58.7 Å²	58.7	20%	0.202	31%	0.312	C	S	.	.	H	α-helix	trans	-64.2	-36.9	174.3	-172.1	155.8	66	0	0	112.3	F193 F361 F362 T368 L369	F193-M365 HydrophobicContact CD2-CE 4.18Å; F193-M365 HydrophobicContact CE1-CE 4.11Å; F193-M365 HydrophobicContact CE2-CE 3.37Å; F193-M365 HydrophobicContact CE2-SD 3.93Å; F193-M365 HydrophobicContact CZ-CE 3.34Å; F193-M365 HydrophobicContact CZ-SD 4.47Å; F361-M365 VanDerWaalsContact O-CB 3.3Å; F361-M365 WeakPolarHBondContact O-CB 3.44Å; F361-M365 PolarHBondContact O-N 3.3Å; F362-M365 PolarHBondContact O-N 2.78Å; M365-T368 PolarHBondContact O-N 2.9Å; M365-L369 HydrophobicContact CG-CD1 3.53Å; M365-L369 HydrophobicContact CG-CG 4.12Å; M365-L369 WeakPolarHBondContact O-CB 3.43Å; M365-L369 WeakPolarHBondContact O-CG 3.31Å; M365-L369 PolarHBondContact O-N 3.03Å; M365-L369 HydrophobicContact SD-CD1 4.25Å
366	L	91.6	Very high	90.7	Very high	52 Å²	52	57 Å²	57	27%	0.272	31%	0.308	S	S	.	.	H	α-helix	trans	-63.6	-46	176.4	-170.9	65.5	0	0	0	111.6	F362 T363 Y364 T368 L369 C370 C373 V375	F362-L366 HydrophobicContact CE1-CD2 4.28Å; F362-L366 WeakPolarHBondContact O-CB 3.13Å; F362-L366 PolarHBondContact O-N 3.46Å; T363-L366 PolarHBondContact O-N 3.03Å; Y364-L366 VanDerWaalsContact C-N 3.32Å; Y364-L366 PolarHBondContact O-N 2.91Å; L366-T368 PolarHBondContact O-N 3.43Å; L366-L369 PolarHBondContact O-N 3.41Å; L366-C370 HydrophobicContact CD1-CB 3.83Å; L366-C370 HydrophobicContact CG-CB 4.35Å; L366-C370 WeakPolarHBondContact O-CA 3.3Å; L366-C370 VanDerWaalsContact O-CB 3.28Å; L366-C370 WeakPolarHBondContact O-CB 3.23Å; L366-C370 PolarHBondContact O-N 3.32Å; L366-C373 HydrophobicContact CD1-CB 4.23Å; L366-C373 HydrophobicContact CD2-CB 4.15Å; L366-C373 HydrophobicContact CG-CB 3.87Å; L366-V375 HydrophobicContact CD2-CG2 4.22Å
367	K	88	Confident	90.3	Very high	103 Å²	103	61.5 Å²	61.5	45%	0.448	34%	0.335	S	S	.	.	H	α-helix	trans	-58.1	-34.2	175.7	-172.6	-169.3	174.7	-142	0	111.7	D179 T363 Y364	D179-K367 IonicContact OD1-NZ 3.95Å; D179-K367 PolarHBondContact OD1-NZ 2.79Å; D179-K367 IonicContact OD2-NZ 3.53Å; T363-K367 WeakPolarHBondContact O-CB 3.01Å; T363-K367 PolarHBondContact O-N 3.49Å; Y364-K367 PolarHBondContact O-N 2.91Å
368	T	88.4	Confident	90	Very high	12 Å²	12	66.6 Å²	66.6	7%	0.074	37%	0.368	C	S	.	.	H	α-helix	trans	-80.3	-41.9	-179.3	-56.7	0	0	0	0	113.7	K181 V184 I185 Y364 M365 L366	K181-T368 HydrophobicContact CB-CG2 3.82Å; K181-T368 HydrophobicContact CG-CG2 3.81Å; V184-T368 HydrophobicContact CB-CG2 4.01Å; V184-T368 HydrophobicContact CG1-CG2 4.24Å; V184-T368 VanDerWaalsContact CG1-OG1 3.23Å; V184-T368 WeakPolarHBondContact CG1-OG1 3.45Å; V184-T368 HydrophobicContact CG2-CG2 4.5Å; I185-T368 HydrophobicContact CG1-CG2 4.42Å; Y364-T368 PolarHBondContact O-N 3.02Å; Y364-T368 PolarHBondContact O-OG1 3.12Å; Y364-T368 VanDerWaalsContact O-OG1 3.09Å; M365-T368 PolarHBondContact O-N 2.9Å; L366-T368 PolarHBondContact O-N 3.43Å
369	L	89.4	Confident	89.8	Confident	107 Å²	107	65.7 Å²	65.7	56%	0.56	37%	0.367	S	S	*	.	H	α-helix	trans	-89.7	-31.8	-173.2	-66.3	178.7	0	0	0	113.2	I185 M365 L366	I185-L369 HydrophobicContact CD1-CD2 3.57Å; I185-L369 HydrophobicContact CG1-CD2 4.02Å; M365-L369 HydrophobicContact CG-CD1 3.53Å; M365-L369 HydrophobicContact CG-CG 4.12Å; M365-L369 WeakPolarHBondContact O-CB 3.43Å; M365-L369 WeakPolarHBondContact O-CG 3.31Å; M365-L369 PolarHBondContact O-N 3.03Å; M365-L369 HydrophobicContact SD-CD1 4.25Å; L366-L369 PolarHBondContact O-N 3.41Å
370	C	86.2	Confident	89.5	Confident	35 Å²	35	66 Å²	66	24%	0.236	37%	0.365	C	S	.	.			trans	-108.7	104.7	-175.1	-178	0	0	0	0	110.6	L366 S372 C373	L366-C370 HydrophobicContact CD1-CB 3.83Å; L366-C370 HydrophobicContact CG-CB 4.35Å; L366-C370 WeakPolarHBondContact O-CA 3.3Å; L366-C370 VanDerWaalsContact O-CB 3.28Å; L366-C370 WeakPolarHBondContact O-CB 3.23Å; L366-C370 PolarHBondContact O-N 3.32Å; C370-S372 VanDerWaalsContact C-N 3.26Å; C370-S372 PolarHBondContact O-N 3.49Å; C370-C373 HydrophobicContact CB-CB 3.56Å; C370-C373 WeakPolarHBondContact CB-SG 3.47Å; C370-C373 PolarHBondContact O-N 3.26Å; C370-C373 WeakPolarHBondContact SG-CB 3.42Å; C370-C373 PolarHBondContact SG-N 3.3Å; C370-C373 CovalentContact SG-SG 2.03Å; C370-C373 PolarHBondContact SG-SG 2.94Å
371	I	80.5	Confident	89.3	Confident	153 Å²	153	69 Å²	69	79%	0.785	38%	0.378	S	S	*	.	T	Hydrogen-bonded Turn	trans	-66.5	-31.7	-179.8	-59.6	168.6	0	0	0	111.2
372	S	85.3	Confident	89.1	Confident	118 Å²	118	74.4 Å²	74.4	83%	0.825	40%	0.402	S	S	*	.	T	Hydrogen-bonded Turn	trans	-89.7	-6.2	-176.4	-44.4	0	0	0	0	113.8	C370 N374	C370-S372 VanDerWaalsContact C-N 3.26Å; C370-S372 PolarHBondContact O-N 3.49Å; S372-N374 PolarHBondContact O-N 3.22Å
373	C	86.9	Confident	89.1	Confident	47 Å²	47	71.9 Å²	71.9	32%	0.318	39%	0.391	S	S	.	.			trans	-88.2	104.6	-176.8	-65.6	0	0	0	0	109.7	L366 C370 V375	L366-C373 HydrophobicContact CD1-CB 4.23Å; L366-C373 HydrophobicContact CD2-CB 4.15Å; L366-C373 HydrophobicContact CG-CB 3.87Å; C370-C373 HydrophobicContact CB-CB 3.56Å; C370-C373 WeakPolarHBondContact CB-SG 3.47Å; C370-C373 PolarHBondContact O-N 3.26Å; C370-C373 WeakPolarHBondContact SG-CB 3.42Å; C370-C373 PolarHBondContact SG-N 3.3Å; C370-C373 CovalentContact SG-SG 2.03Å; C370-C373 PolarHBondContact SG-SG 2.94Å; C373-V375 PolarHBondContact O-N 2.95Å
374	N	84.6	Confident	89	Confident	157 Å²	157	72.3 Å²	72.3	84%	0.84	39%	0.392	S	S	*	.			trans	-85.8	104.8	176.9	-166.1	12.1	0	0	0	110.5	S372	S372-N374 PolarHBondContact O-N 3.22Å
375	V	88.1	Confident	89.1	Confident	28 Å²	28	73.6 Å²	73.6	17%	0.17	40%	0.397	C	S	.	.			trans	-94.5	117.1	172.8	-178.1	0	0	0	0	108.4	T363 L366 C373 T377 F380	T363-V375 HydrophobicContact CG2-CG1 4.28Å; L366-V375 HydrophobicContact CD2-CG2 4.22Å; C373-V375 PolarHBondContact O-N 2.95Å; V375-T377 PolarHBondContact O-N 3.03Å; V375-F380 HydrophobicContact CG1-CB 4.28Å
376	P	91.4	Very high	89.1	Confident	74 Å²	74	74.9 Å²	74.9	48%	0.481	40%	0.402	S	S	.	.			trans	-58.2	134.3	178.6	-24.2	33.4	0	0	0	111.8	T378 L379 F380	P376-T378 PolarHBondContact O-N 3.11Å; P376-L379 HydrophobicContact CB-CB 4.21Å; P376-L379 WeakPolarHBondContact O-CA 3.43Å; P376-L379 WeakPolarHBondContact O-CB 3.43Å; P376-L379 PolarHBondContact O-N 3.12Å; P376-F380 PolarHBondContact O-N 3.13Å
377	T	86.6	Confident	89.2	Confident	97 Å²	97	72.4 Å²	72.4	60%	0.595	39%	0.389	S	S	*	.	H	α-helix	trans	-55.6	-38.5	-178.9	-49.9	0	0	0	0	112.4	V375 L379 F380 K381	V375-T377 PolarHBondContact O-N 3.03Å; T377-L379 VanDerWaalsContact C-N 3.33Å; T377-L379 PolarHBondContact O-N 2.94Å; T377-F380 PolarHBondContact O-N 2.57Å; T377-K381 HydrophobicContact CG2-CD 4.2Å; T377-K381 HydrophobicContact CG2-CG 4.49Å; T377-K381 WeakPolarHBondContact O-CB 2.93Å; T377-K381 WeakPolarHBondContact O-CG 3.34Å; T377-K381 PolarHBondContact O-N 3.33Å
378	T	88.3	Confident	89.5	Confident	118 Å²	118	67.7 Å²	67.7	72%	0.724	37%	0.368	S	S	*	.	H	α-helix	trans	-61.8	-40.3	176.3	-46.8	0	0	0	0	111.9	P376 F382	P376-T378 PolarHBondContact O-N 3.11Å; T378-F382 VanDerWaalsContact O-CB 3.31Å; T378-F382 WeakPolarHBondContact O-CB 3.38Å; T378-F382 PolarHBondContact O-N 2.93Å
379	L	91.1	Very high	89.6	Confident	72 Å²	72	68.6 Å²	68.6	38%	0.377	37%	0.374	S	S	.	.	H	α-helix	trans	-70.2	-41.8	178.2	-176.5	64.4	0	0	0	111.2	P376 T377 F382 F383	P376-L379 HydrophobicContact CB-CB 4.21Å; P376-L379 WeakPolarHBondContact O-CA 3.43Å; P376-L379 WeakPolarHBondContact O-CB 3.43Å; P376-L379 PolarHBondContact O-N 3.12Å; T377-L379 VanDerWaalsContact C-N 3.33Å; T377-L379 PolarHBondContact O-N 2.94Å; L379-F382 WeakPolarHBondContact O-CB 3.37Å; L379-F382 PolarHBondContact O-N 3.01Å; L379-F383 HydrophobicContact CD1-CD2 4.42Å; L379-F383 HydrophobicContact CD1-CE1 4.2Å; L379-F383 HydrophobicContact CD1-CE2 3.8Å; L379-F383 HydrophobicContact CD1-CZ 3.67Å; L379-F383 HydrophobicContact CD2-CE2 4.1Å; L379-F383 HydrophobicContact CG-CD2 4.18Å; L379-F383 HydrophobicContact CG-CE2 3.69Å; L379-F383 HydrophobicContact CG-CZ 4.1Å; L379-F383 PolarHBondContact O-N 3.47Å
380	F	90.8	Very high	89.7	Confident	31 Å²	31	63.5 Å²	63.5	14%	0.136	35%	0.348	C	S	.	.	H	α-helix	trans	-60.1	-47.6	176	-175.5	-99.1	0	0	0	111.7	I177 F360 Y364 V375 P376 T377 F382 F383 F384	I177-F380 HydrophobicContact CD1-CE1 4.18Å; I177-F380 HydrophobicContact CD1-CZ 4.28Å; F360-F380 HydrophobicContact CD2-CE2 4.29Å; F360-F380 HydrophobicContact CD2-CZ 4.29Å; F360-F380 HydrophobicContact CE2-CE1 4.02Å; F360-F380 AromaticContact CE2-CE2 3.92Å; F360-F380 HydrophobicContact CE2-CE2 3.92Å; F360-F380 AromaticContact CE2-CZ 3.51Å; F360-F380 HydrophobicContact CE2-CZ 3.51Å; F360-F380 HydrophobicContact CZ-CZ 4.26Å; Y364-F380 HydrophobicContact CD2-CE2 4.12Å; Y364-F380 AromaticContact CD2-CZ 3.94Å; Y364-F380 HydrophobicContact CD2-CZ 3.94Å; Y364-F380 HydrophobicContact CG-CE2 4.38Å; Y364-F380 HydrophobicContact CG-CZ 4.38Å; V375-F380 HydrophobicContact CG1-CB 4.28Å; P376-F380 PolarHBondContact O-N 3.13Å; T377-F380 PolarHBondContact O-N 2.57Å; F380-F382 PolarHBondContact O-N 3.31Å; F380-F383 PolarHBondContact O-N 3.33Å; F380-F384 PolarHBondContact O-N 2.93Å
381	K	89.6	Confident	90	Very high	73 Å²	73	62 Å²	62	32%	0.317	34%	0.338	S	S	.	.	H	α-helix	trans	-62.4	-41.1	174.8	-71.7	175.8	172.5	-166.8	0	111.9	E81 T377 F383 F384 W385	E81-K381 IonicContact OE1-NZ 3.9Å; E81-K381 PolarHBondContact OE1-NZ 3.49Å; E81-K381 VanDerWaalsContact OE2-CD 3.3Å; E81-K381 WeakPolarHBondContact OE2-CD 3.42Å; E81-K381 WeakPolarHBondContact OE2-CE 3.31Å; E81-K381 IonicContact OE2-NZ 2.65Å; E81-K381 PolarHBondContact OE2-NZ 3.2Å; T377-K381 HydrophobicContact CG2-CD 4.2Å; T377-K381 HydrophobicContact CG2-CG 4.49Å; T377-K381 WeakPolarHBondContact O-CB 2.93Å; T377-K381 WeakPolarHBondContact O-CG 3.34Å; T377-K381 PolarHBondContact O-N 3.33Å; K381-F383 PolarHBondContact O-N 2.94Å; K381-F384 WeakPolarHBondContact O-CB 2.9Å; K381-F384 PolarHBondContact O-N 3.12Å; K381-W385 PolarHBondContact O-N 3.37Å
382	F	91.5	Very high	90.5	Very high	126 Å²	126	55.5 Å²	55.5	55%	0.553	31%	0.306	S	S	*	.	H	α-helix	trans	-58.2	-47.2	175.9	174.1	-96.8	0	0	0	111.7	T378 L379 F380 F384 W385 F386	T378-F382 VanDerWaalsContact O-CB 3.31Å; T378-F382 WeakPolarHBondContact O-CB 3.38Å; T378-F382 PolarHBondContact O-N 2.93Å; L379-F382 WeakPolarHBondContact O-CB 3.37Å; L379-F382 PolarHBondContact O-N 3.01Å; F380-F382 PolarHBondContact O-N 3.31Å; F382-F384 VanDerWaalsContact C-N 3.35Å; F382-F384 PolarHBondContact O-N 3.2Å; F382-W385 PolarHBondContact O-N 2.83Å; F382-F386 WeakPolarHBondContact O-CB 3.28Å; F382-F386 PolarHBondContact O-N 2.82Å
383	F	95.1	Very high	90.8	Very high	43 Å²	43	52.8 Å²	52.8	19%	0.189	28%	0.283	C	S	.	.	H	α-helix	trans	-66.1	-35.7	176.7	-68.2	-33.7	0	0	0	113.2	P359 F360 T363 L379 F380 K381 F386 G387	P359-F383 HydrophobicContact CB-CB 4.14Å; P359-F383 HydrophobicContact CB-CD1 3.41Å; P359-F383 VanDerWaalsContact CB-CD1 3.41Å; P359-F383 HydrophobicContact CB-CD2 3.92Å; P359-F383 HydrophobicContact CB-CE1 3.65Å; P359-F383 HydrophobicContact CB-CE2 4.12Å; P359-F383 HydrophobicContact CB-CG 3.56Å; P359-F383 HydrophobicContact CB-CZ 3.99Å; P359-F383 HydrophobicContact CG-CD1 4.34Å; P359-F383 HydrophobicContact CG-CE1 4.45Å; F360-F383 HydrophobicContact CB-CB 4.13Å; T363-F383 HydrophobicContact CG2-CD2 3.69Å; T363-F383 HydrophobicContact CG2-CE2 3.69Å; L379-F383 HydrophobicContact CD1-CD2 4.42Å; L379-F383 HydrophobicContact CD1-CE1 4.2Å; L379-F383 HydrophobicContact CD1-CE2 3.8Å; L379-F383 HydrophobicContact CD1-CZ 3.67Å; L379-F383 HydrophobicContact CD2-CE2 4.1Å; L379-F383 HydrophobicContact CG-CD2 4.18Å; L379-F383 HydrophobicContact CG-CE2 3.69Å; L379-F383 HydrophobicContact CG-CZ 4.1Å; L379-F383 PolarHBondContact O-N 3.47Å; F380-F383 PolarHBondContact O-N 3.33Å; K381-F383 PolarHBondContact O-N 2.94Å; F383-F386 PolarHBondContact O-N 2.9Å; F383-G387 PolarHBondContact O-N 2.94Å; F383-G387 VanDerWaalsContact O-N 3.12Å
384	F	92.1	Very high	90.8	Very high	19 Å²	19	50.6 Å²	50.6	8%	0.083	27%	0.268	C	S	.	.	H	α-helix	trans	-58.8	-50.8	172.6	-176.2	-109.2	0	0	0	111.6	D100 I177 F360 F380 K381 F382 F386 G387 Y388	D100-F384 VanDerWaalsContact OD2-CE2 3.23Å; D100-F384 WeakPolarHBondContact OD2-CE2 3.28Å; D100-F384 VanDerWaalsContact OD2-CZ 3.28Å; D100-F384 WeakPolarHBondContact OD2-CZ 3.38Å; I177-F384 HydrophobicContact CD1-CE2 4.36Å; F360-F384 HydrophobicContact CD2-CB 3.86Å; F360-F384 AromaticContact CD2-CD2 3.95Å; F360-F384 HydrophobicContact CD2-CD2 3.95Å; F360-F384 HydrophobicContact CD2-CG 4.44Å; F360-F384 HydrophobicContact CE1-CD2 4.31Å; F360-F384 HydrophobicContact CE2-CB 3.97Å; F360-F384 AromaticContact CE2-CD2 3.45Å; F360-F384 HydrophobicContact CE2-CD2 3.45Å; F360-F384 VanDerWaalsContact CE2-CD2 3.45Å; F360-F384 HydrophobicContact CE2-CE2 4.36Å; F360-F384 HydrophobicContact CE2-CG 4.17Å; F360-F384 AromaticContact CZ-CD2 3.65Å; F360-F384 HydrophobicContact CZ-CD2 3.65Å; F360-F384 HydrophobicContact CZ-CE2 4.16Å; F380-F384 PolarHBondContact O-N 2.93Å; K381-F384 WeakPolarHBondContact O-CB 2.9Å; K381-F384 PolarHBondContact O-N 3.12Å; F382-F384 VanDerWaalsContact C-N 3.35Å; F382-F384 PolarHBondContact O-N 3.2Å; F384-F386 VanDerWaalsContact C-N 3.34Å; F384-F386 PolarHBondContact O-N 2.74Å; F384-G387 PolarHBondContact O-N 3.13Å; F384-Y388 AromaticContact CD1-CE2 3.93Å; F384-Y388 HydrophobicContact CD1-CE2 3.93Å; F384-Y388 AromaticContact CE1-CE2 3.53Å; F384-Y388 HydrophobicContact CE1-CE2 3.53Å; F384-Y388 AromaticContact CE1-CZ 3.81Å; F384-Y388 WeakPolarHBondContact CE1-OH 3.07Å; F384-Y388 AromaticContact CZ-CE2 3.98Å; F384-Y388 HydrophobicContact CZ-CE2 3.98Å; F384-Y388 AromaticContact CZ-CZ 3.76Å; F384-Y388 WeakPolarHBondContact CZ-OH 3.31Å
385	W	92.5	Very high	91.1	Very high	39 Å²	39	43.5 Å²	43.5	15%	0.148	23%	0.23	C	C	.	.	H	α-helix	trans	-66.4	-33.5	177.5	-77.1	105.3	0	0	0	113.3	V27 M74 L78 K381 F382 G387 Y388	V27-W385 HydrophobicContact CB-CH2 4.44Å; V27-W385 HydrophobicContact CB-CZ3 4.2Å; V27-W385 HydrophobicContact CG1-CH2 3.72Å; V27-W385 HydrophobicContact CG1-CZ3 3.51Å; V27-W385 HydrophobicContact CG2-CD2 4.48Å; V27-W385 HydrophobicContact CG2-CE3 3.89Å; V27-W385 HydrophobicContact CG2-CH2 3.83Å; V27-W385 HydrophobicContact CG2-CZ2 4.39Å; V27-W385 HydrophobicContact CG2-CZ3 3.55Å; M74-W385 HydrophobicContact CE-CE3 4.49Å; M74-W385 HydrophobicContact CE-CZ3 3.98Å; L78-W385 HydrophobicContact CB-CH2 4.03Å; L78-W385 HydrophobicContact CB-CZ2 4.44Å; K381-W385 PolarHBondContact O-N 3.37Å; F382-W385 PolarHBondContact O-N 2.83Å; W385-G387 VanDerWaalsContact C-N 3.26Å; W385-G387 PolarHBondContact O-N 3.18Å; W385-Y388 HydrophobicContact CD2-CD2 4.29Å; W385-Y388 AromaticContact CE3-CD2 3.67Å; W385-Y388 HydrophobicContact CE3-CD2 3.67Å; W385-Y388 HydrophobicContact CE3-CE2 4.22Å; W385-Y388 HydrophobicContact CZ3-CD2 4.01Å; W385-Y388 HydrophobicContact CZ3-CE2 4.32Å; W385-Y388 PolarHBondContact O-N 2.89Å
386	F	93.7	Very high	91.1	Very high	69 Å²	69	47 Å²	47	30%	0.303	25%	0.247	S	C	.	.	H	α-helix	trans	-63.3	-33.1	175.2	-173.9	-118.7	0	0	0	112.4	I355 C356 F382 F383 F384 Y388 C389	I355-F386 HydrophobicContact CG2-CE1 4.25Å; I355-F386 HydrophobicContact CG2-CZ 4.26Å; I355-F386 VanDerWaalsContact O-CE1 3.31Å; I355-F386 WeakPolarHBondContact O-CE1 3.13Å; C356-F386 HydrophobicContact CB-CE1 4.48Å; C356-F386 WeakPolarHBondContact O-CD1 3.16Å; F382-F386 WeakPolarHBondContact O-CB 3.28Å; F382-F386 PolarHBondContact O-N 2.82Å; F383-F386 PolarHBondContact O-N 2.9Å; F384-F386 VanDerWaalsContact C-N 3.34Å; F384-F386 PolarHBondContact O-N 2.74Å; F386-Y388 VanDerWaalsContact C-N 3.32Å; F386-Y388 PolarHBondContact O-N 3.46Å; F386-C389 WeakPolarHBondContact O-CB 3.5Å; F386-C389 PolarHBondContact O-N 3.34Å
387	G	93.4	Very high	90.9	Very high	0 Å²	0	44.1 Å²	44.1	0%	0	23%	0.228	C	C	.	.	H	α-helix	trans	-56.9	-43.4	171.8	0	0	0	0	0	112.6	W357 F383 F384 W385 C389 N390	W357-G387 PolarHBondContact NE1-O 3.11Å; F383-G387 PolarHBondContact O-N 2.94Å; F383-G387 VanDerWaalsContact O-N 3.12Å; F384-G387 PolarHBondContact O-N 3.13Å; W385-G387 VanDerWaalsContact C-N 3.26Å; W385-G387 PolarHBondContact O-N 3.18Å; G387-C389 VanDerWaalsContact C-N 3.25Å; G387-C389 PolarHBondContact O-N 3.41Å; G387-N390 WeakPolarHBondContact O-CB 3.5Å; G387-N390 PolarHBondContact O-N 3.32Å; G387-N390 VanDerWaalsContact O-N 3.11Å
388	Y	93.6	Very high	90.9	Very high	3 Å²	3	40.2 Å²	40.2	1%	0.012	20%	0.202	C	C	.	.	H	α-helix	trans	-64.9	-25.4	179.2	-65.7	-48.1	0	0	0	114	V69 V73 M74 S77 D100 F384 W385 F386 N390 S391	V69-Y388 HydrophobicContact CG1-CD1 3.51Å; V69-Y388 HydrophobicContact CG1-CE1 3.64Å; V73-Y388 HydrophobicContact CG1-CE1 4.23Å; V73-Y388 WeakPolarHBondContact CG1-OH 3.46Å; M74-Y388 HydrophobicContact CG-CD1 4.26Å; M74-Y388 HydrophobicContact CG-CD2 4.25Å; M74-Y388 HydrophobicContact CG-CE1 4.49Å; M74-Y388 HydrophobicContact CG-CE2 4.48Å; M74-Y388 HydrophobicContact CG-CG 4.14Å; M74-Y388 HydrophobicContact SD-CG 4.39Å; S77-Y388 PolarHBondContact OG-OH 2.92Å; D100-Y388 PolarHBondContact OD1-OH 3.48Å; F384-Y388 AromaticContact CD1-CE2 3.93Å; F384-Y388 HydrophobicContact CD1-CE2 3.93Å; F384-Y388 AromaticContact CE1-CE2 3.53Å; F384-Y388 HydrophobicContact CE1-CE2 3.53Å; F384-Y388 AromaticContact CE1-CZ 3.81Å; F384-Y388 WeakPolarHBondContact CE1-OH 3.07Å; F384-Y388 AromaticContact CZ-CE2 3.98Å; F384-Y388 HydrophobicContact CZ-CE2 3.98Å; F384-Y388 AromaticContact CZ-CZ 3.76Å; F384-Y388 WeakPolarHBondContact CZ-OH 3.31Å; W385-Y388 HydrophobicContact CD2-CD2 4.29Å; W385-Y388 AromaticContact CE3-CD2 3.67Å; W385-Y388 HydrophobicContact CE3-CD2 3.67Å; W385-Y388 HydrophobicContact CE3-CE2 4.22Å; W385-Y388 HydrophobicContact CZ3-CD2 4.01Å; W385-Y388 HydrophobicContact CZ3-CE2 4.32Å; W385-Y388 PolarHBondContact O-N 2.89Å; F386-Y388 VanDerWaalsContact C-N 3.32Å; F386-Y388 PolarHBondContact O-N 3.46Å; Y388-N390 PolarHBondContact O-N 3.27Å; Y388-N390 VanDerWaalsContact O-N 3.16Å; Y388-S391 PolarHBondContact O-N 3.41Å
389	C	90.4	Very high	90.8	Very high	31 Å²	31	36.1 Å²	36.1	21%	0.209	18%	0.177	C	C	.	.	H	α-helix	trans	-60.5	-25.1	175.2	-62.9	0	0	0	0	112.5	F386 G387 S391 A392 L393	F386-C389 WeakPolarHBondContact O-CB 3.5Å; F386-C389 PolarHBondContact O-N 3.34Å; G387-C389 VanDerWaalsContact C-N 3.25Å; G387-C389 PolarHBondContact O-N 3.41Å; C389-S391 VanDerWaalsContact C-N 3.26Å; C389-S391 PolarHBondContact O-N 3.39Å; C389-A392 WeakPolarHBondContact O-CB 3.4Å; C389-A392 PolarHBondContact O-N 2.91Å; C389-A392 VanDerWaalsContact O-N 3.08Å; C389-L393 WeakPolarHBondContact O-CG 3.4Å; C389-L393 PolarHBondContact O-N 3.47Å
390	N	91.5	Very high	90.4	Very high	1 Å²	1	37 Å²	37	1%	0.005	19%	0.185	C	C	.	.	H	α-helix	trans	-53.1	-43.9	175.4	177	71.5	0	0	0	112.4	F353 C356 G387 Y388 A392 L393 N394	F353-N390 WeakPolarHBondContact CA-OD1 3.34Å; F353-N390 WeakPolarHBondContact CD2-ND2 3.34Å; C356-N390 HydrophobicContact CB-CB 3.85Å; G387-N390 WeakPolarHBondContact O-CB 3.5Å; G387-N390 PolarHBondContact O-N 3.32Å; G387-N390 VanDerWaalsContact O-N 3.11Å; Y388-N390 PolarHBondContact O-N 3.27Å; Y388-N390 VanDerWaalsContact O-N 3.16Å; N390-A392 PolarHBondContact O-N 2.95Å; N390-L393 PolarHBondContact O-N 2.86Å; N390-L393 VanDerWaalsContact O-N 3.11Å; N390-N394 PolarHBondContact O-N 2.99Å
391	S	92.4	Very high	89.8	Confident	4 Å²	4	37.8 Å²	37.8	3%	0.028	19%	0.189	C	C	.	.	H	α-helix	trans	-64.9	-26.7	-178.7	-65	0	0	0	0	113.1	N38 D66 Y388 C389	N38-S391 PolarHBondContact ND2-O 3.04Å; D66-S391 WeakPolarHBondContact OD1-CA 3.3Å; D66-S391 WeakPolarHBondContact OD1-CB 3.48Å; D66-S391 PolarHBondContact OD1-OG 3.36Å; Y388-S391 PolarHBondContact O-N 3.41Å; C389-S391 VanDerWaalsContact C-N 3.26Å; C389-S391 PolarHBondContact O-N 3.39Å
392	A	91.8	Very high	89.4	Confident	15 Å²	15	36.3 Å²	36.3	12%	0.124	18%	0.184	C	C	.	.	H	α-helix	trans	-79.5	-31.3	175.2	0	0	0	0	0	112.2	M30 I34 C389 N390	M30-A392 HydrophobicContact SD-CB 4.45Å; I34-A392 HydrophobicContact CD1-CB 4.46Å; I34-A392 HydrophobicContact CG1-CB 3.66Å; C389-A392 WeakPolarHBondContact O-CB 3.4Å; C389-A392 PolarHBondContact O-N 2.91Å; C389-A392 VanDerWaalsContact O-N 3.08Å; N390-A392 PolarHBondContact O-N 2.95Å
393	L	90.8	Very high	89.1	Confident	62 Å²	62	33 Å²	33	33%	0.325	17%	0.172	S	C	.	.	H	α-helix	trans	-74.9	-28	-177.6	-66.8	171.9	0	0	0	112.4	V352 C389 N390 L396 I397	V352-L393 HydrophobicContact CG1-CB 4Å; V352-L393 HydrophobicContact CG1-CD1 3.44Å; V352-L393 VanDerWaalsContact CG1-CD1 3.44Å; V352-L393 HydrophobicContact CG1-CG 4.35Å; C389-L393 WeakPolarHBondContact O-CG 3.4Å; C389-L393 PolarHBondContact O-N 3.47Å; N390-L393 PolarHBondContact O-N 2.86Å; N390-L393 VanDerWaalsContact O-N 3.11Å; L393-L396 HydrophobicContact CD2-CD1 4.22Å; L393-L396 WeakPolarHBondContact O-CB 3.37Å; L393-L396 PolarHBondContact O-N 3.07Å; L393-L396 VanDerWaalsContact O-N 3.09Å; L393-I397 HydrophobicContact CB-CD1 4.29Å; L393-I397 VanDerWaalsContact O-CG1 3.25Å; L393-I397 WeakPolarHBondContact O-CG1 3.28Å; L393-I397 PolarHBondContact O-N 3.46Å
394	N	88.4	Confident	88.6	Confident	1 Å²	1	34.2 Å²	34.2	1%	0.005	18%	0.181	C	C	.	.	H	α-helix	trans	-52.4	-56.5	-178.1	-75.9	-23.9	0	0	0	113.5	D66 N390 L396 I397 Y398	D66-N394 PolarHBondContact OD2-ND2 3.21Å; N390-N394 PolarHBondContact O-N 2.99Å; N394-L396 VanDerWaalsContact C-N 3.31Å; N394-L396 PolarHBondContact O-N 3.47Å; N394-I397 PolarHBondContact O-N 2.9Å; N394-Y398 HydrophobicContact CB-CE2 4.22Å; N394-Y398 WeakPolarHBondContact O-CD2 3.33Å; N394-Y398 WeakPolarHBondContact O-CE2 3.45Å; N394-Y398 PolarHBondContact O-N 3.24Å; N394-Y398 VanDerWaalsContact O-N 3.13Å
395	P	90.7	Very high	88.3	Confident	7 Å²	7	33.4 Å²	33.4	5%	0.045	18%	0.177	C	C	.	.	H	α-helix	trans	-57.2	-38.3	174.4	-26.6	34.4	0	0	0	114.4	N38 V41 Y398 T399	N38-P395 WeakPolarHBondContact OD1-CG 3.49Å; V41-P395 HydrophobicContact CG2-CB 4.04Å; V41-P395 HydrophobicContact CG2-CG 4.11Å; P395-Y398 PolarHBondContact O-N 3.38Å; P395-T399 WeakPolarHBondContact O-CG2 3.47Å; P395-T399 PolarHBondContact O-N 2.95Å; P395-T399 PolarHBondContact O-OG1 3.23Å
396	L	88.3	Confident	88.2	Confident	102 Å²	102	38.4 Å²	38.4	53%	0.534	20%	0.196	S	C	.	.	H	α-helix	trans	-63.8	-45.5	179.4	-65	176.5	0	0	0	110.8	L393 N394 Y398 T399 V400	L393-L396 HydrophobicContact CD2-CD1 4.22Å; L393-L396 WeakPolarHBondContact O-CB 3.37Å; L393-L396 PolarHBondContact O-N 3.07Å; L393-L396 VanDerWaalsContact O-N 3.09Å; N394-L396 VanDerWaalsContact C-N 3.31Å; N394-L396 PolarHBondContact O-N 3.47Å; L396-Y398 VanDerWaalsContact C-N 3.31Å; L396-Y398 PolarHBondContact O-N 2.03Å; L396-T399 PolarHBondContact O-N 3.32Å; L396-T399 VanDerWaalsContact O-N 3.14Å; L396-T399 PolarHBondContact O-OG1 3.38Å; L396-V400 WeakPolarHBondContact O-CG2 3.18Å; L396-V400 PolarHBondContact O-N 3.49Å
397	I	86.9	Confident	87.9	Confident	13 Å²	13	44 Å²	44	7%	0.067	22%	0.215	C	C	.	.	H	α-helix	trans	-59.8	-44.5	177.1	-61.3	163.1	0	0	0	109.7	V345 V348 V349 V352 L393 N394 T399 V400 F401	V345-I397 HydrophobicContact CG1-CG2 4.41Å; V348-I397 HydrophobicContact CG1-CG2 4.49Å; V349-I397 HydrophobicContact CG2-CB 4.4Å; V349-I397 HydrophobicContact CG2-CD1 4.48Å; V349-I397 HydrophobicContact CG2-CG2 3.45Å; V349-I397 VanDerWaalsContact CG2-CG2 3.45Å; V352-I397 HydrophobicContact CB-CD1 4.1Å; V352-I397 HydrophobicContact CG1-CD1 4.14Å; V352-I397 HydrophobicContact CG2-CD1 4.01Å; L393-I397 HydrophobicContact CB-CD1 4.29Å; L393-I397 VanDerWaalsContact O-CG1 3.25Å; L393-I397 WeakPolarHBondContact O-CG1 3.28Å; L393-I397 PolarHBondContact O-N 3.46Å; N394-I397 PolarHBondContact O-N 2.9Å; I397-T399 VanDerWaalsContact C-N 3.33Å; I397-T399 PolarHBondContact O-N 3.48Å; I397-V400 PolarHBondContact O-N 3.45Å; I397-F401 HydrophobicContact CG2-CD2 3.63Å; I397-F401 HydrophobicContact CG2-CE2 4.02Å; I397-F401 WeakPolarHBondContact O-CB 3.3Å; I397-F401 VanDerWaalsContact O-CD2 3.24Å; I397-F401 WeakPolarHBondContact O-CD2 3.49Å; I397-F401 PolarHBondContact O-N 3.14Å; I397-F401 VanDerWaalsContact O-N 3.14Å
398	Y	85.7	Confident	87.6	Confident	16 Å²	16	44.5 Å²	44.5	6%	0.063	22%	0.218	C	C	.	.	H	α-helix	trans	-60.8	-40.5	176.7	-54.9	-35.7	0	0	0	112.7	V41 L59 L62 N394 P395 L396 N402	V41-Y398 HydrophobicContact CG1-CD2 4.38Å; V41-Y398 HydrophobicContact CG1-CE2 4.44Å; V41-Y398 HydrophobicContact CG2-CD2 3.82Å; V41-Y398 HydrophobicContact CG2-CE2 4.29Å; L59-Y398 HydrophobicContact CD2-CE1 3.85Å; L59-Y398 HydrophobicContact CD2-CE2 4.49Å; L62-Y398 VanDerWaalsContact CD2-OH 3.3Å; L62-Y398 WeakPolarHBondContact CD2-OH 3.43Å; N394-Y398 HydrophobicContact CB-CE2 4.22Å; N394-Y398 WeakPolarHBondContact O-CD2 3.33Å; N394-Y398 WeakPolarHBondContact O-CE2 3.45Å; N394-Y398 PolarHBondContact O-N 3.24Å; N394-Y398 VanDerWaalsContact O-N 3.13Å; P395-Y398 PolarHBondContact O-N 3.38Å; L396-Y398 VanDerWaalsContact C-N 3.31Å; L396-Y398 PolarHBondContact O-N 2.03Å; Y398-N402 WeakPolarHBondContact O-CA 3.06Å; Y398-N402 WeakPolarHBondContact O-CB 3.49Å; Y398-N402 PolarHBondContact O-N 3.45Å
399	T	85.8	Confident	87.4	Confident	32 Å²	32	45.2 Å²	45.2	20%	0.196	22%	0.222	C	C	.	.	H	α-helix	trans	-71	-39.9	-179.7	58.4	0	0	0	0	114.1	P395 L396 I397 F401 F409	P395-T399 WeakPolarHBondContact O-CG2 3.47Å; P395-T399 PolarHBondContact O-N 2.95Å; P395-T399 PolarHBondContact O-OG1 3.23Å; L396-T399 PolarHBondContact O-N 3.32Å; L396-T399 VanDerWaalsContact O-N 3.14Å; L396-T399 PolarHBondContact O-OG1 3.38Å; I397-T399 VanDerWaalsContact C-N 3.33Å; I397-T399 PolarHBondContact O-N 3.48Å; T399-F401 VanDerWaalsContact C-N 3.32Å; T399-F409 HydrophobicContact CG2-CD2 3.21Å; T399-F409 HydrophobicContact CG2-CE2 3.22Å; T399-F409 HydrophobicContact CG2-CG 4.24Å; T399-F409 HydrophobicContact CG2-CZ 4.27Å
400	V	83.5	Confident	87.3	Confident	91 Å²	91	50.8 Å²	50.8	55%	0.552	24%	0.242	S	C	*	.	H	α-helix	trans	-65.1	-41.8	179	170.2	0	0	0	0	110.3	L396 I397	L396-V400 WeakPolarHBondContact O-CG2 3.18Å; L396-V400 PolarHBondContact O-N 3.49Å; I397-V400 PolarHBondContact O-N 3.45Å
401	F	77.6	Confident	87.2	Confident	47 Å²	47	58.4 Å²	58.4	21%	0.206	28%	0.276	C	S	.	.	H	α-helix	trans	-102.2	-23.8	-165.7	-74.4	-59.6	0	0	0	115.1	F344 V345 V348 I397 T399	F344-F401 HydrophobicContact CD1-CE1 4.01Å; F344-F401 AromaticContact CE1-CE1 3.71Å; F344-F401 HydrophobicContact CE1-CE1 3.71Å; F344-F401 HydrophobicContact CE1-CZ 4.01Å; V345-F401 HydrophobicContact CB-CB 3.98Å; V345-F401 HydrophobicContact CB-CG 4.15Å; V345-F401 HydrophobicContact CG1-CB 3.43Å; V345-F401 VanDerWaalsContact CG1-CB 3.43Å; V345-F401 HydrophobicContact CG1-CD2 4.01Å; V345-F401 HydrophobicContact CG1-CG 3.82Å; V345-F401 HydrophobicContact CG2-CB 3.3Å; V345-F401 HydrophobicContact CG2-CD1 3.67Å; V345-F401 HydrophobicContact CG2-CD2 4.39Å; V345-F401 HydrophobicContact CG2-CG 3.53Å; V348-F401 HydrophobicContact CB-CE2 4.18Å; V348-F401 HydrophobicContact CB-CZ 4.41Å; V348-F401 HydrophobicContact CG1-CE2 3.81Å; V348-F401 HydrophobicContact CG1-CZ 4.21Å; V348-F401 HydrophobicContact CG2-CE2 4.38Å; V348-F401 HydrophobicContact CG2-CZ 4.1Å; I397-F401 HydrophobicContact CG2-CD2 3.63Å; I397-F401 HydrophobicContact CG2-CE2 4.02Å; I397-F401 WeakPolarHBondContact O-CB 3.3Å; I397-F401 VanDerWaalsContact O-CD2 3.24Å; I397-F401 WeakPolarHBondContact O-CD2 3.49Å; I397-F401 PolarHBondContact O-N 3.14Å; I397-F401 VanDerWaalsContact O-N 3.14Å; T399-F401 VanDerWaalsContact C-N 3.32Å
402	N	82.3	Confident	86.9	Confident	41 Å²	41	60.6 Å²	60.6	22%	0.219	29%	0.286	C	S	.	.			trans	-112.9	107.6	179.7	-170.8	-26.9	0	0	0	111.5	Y398 D404 F405 R406	Y398-N402 WeakPolarHBondContact O-CA 3.06Å; Y398-N402 WeakPolarHBondContact O-CB 3.49Å; Y398-N402 PolarHBondContact O-N 3.45Å; N402-D404 PolarHBondContact O-N 3.02Å; N402-D404 WeakPolarHBondContact OD1-CB 3.4Å; N402-D404 PolarHBondContact OD1-N 3.29Å; N402-F405 HydrophobicContact CB-CB 4.22Å; N402-F405 HydrophobicContact CB-CD2 3.8Å; N402-F405 WeakPolarHBondContact ND2-CD2 3Å; N402-F405 PolarHBondContact O-N 3.45Å; N402-F405 PolarHBondContact OD1-N 2.94Å; N402-R406 PolarHBondContact O-N 3.38Å
403	N	83.8	Confident	86.8	Confident	57 Å²	57	64.6 Å²	64.6	31%	0.305	31%	0.305	S	S	.	.	H	α-helix	trans	-59.6	-30.6	179	-75.8	-38.2	0	0	0	113.4	R406 R407	N403-R406 PolarHBondContact OD1-NH2 2.75Å; N403-R407 WeakPolarHBondContact O-CB 3.3Å; N403-R407 VanDerWaalsContact O-CG 3.3Å; N403-R407 WeakPolarHBondContact O-CG 3.48Å; N403-R407 PolarHBondContact O-N 3.25Å
404	D	85.8	Confident	86.6	Confident	69 Å²	69	65.2 Å²	65.2	37%	0.369	31%	0.314	S	S	.	.	H	α-helix	trans	-73.7	-37.1	-179.6	-62.9	-39.8	0	0	0	111.2	L51 N402 S408	L51-D404 HydrophobicContact CD2-CB 3.83Å; L51-D404 HydrophobicContact CG-CB 4.37Å; N402-D404 PolarHBondContact O-N 3.02Å; N402-D404 WeakPolarHBondContact OD1-CB 3.4Å; N402-D404 PolarHBondContact OD1-N 3.29Å; D404-S408 VanDerWaalsContact O-CB 3.32Å; D404-S408 WeakPolarHBondContact O-CB 3.29Å; D404-S408 PolarHBondContact O-N 2.91Å; D404-S408 PolarHBondContact O-OG 3.16Å
405	F	86.6	Confident	85.3	Confident	1 Å²	1	74.6 Å²	74.6	0%	0.004	35%	0.354	C	S	.	.	H	α-helix	trans	-63.2	-49.3	169.5	-87.7	-68.8	0	0	0	111	V41 A44 V45 L51 L59 N402 R407 S408 F409	V41-F405 HydrophobicContact CG1-CE1 4.16Å; V41-F405 HydrophobicContact CG1-CZ 4.48Å; A44-F405 HydrophobicContact CB-CD1 4.18Å; A44-F405 HydrophobicContact CB-CE1 4.27Å; V45-F405 HydrophobicContact CG2-CE1 3.89Å; V45-F405 HydrophobicContact CG2-CZ 3.84Å; L51-F405 HydrophobicContact CD1-CD1 3.78Å; L51-F405 HydrophobicContact CD1-CE1 3.85Å; L51-F405 HydrophobicContact CD1-CG 4.17Å; L51-F405 HydrophobicContact CD1-CZ 4.31Å; L51-F405 HydrophobicContact CD2-CD2 4.14Å; L51-F405 HydrophobicContact CD2-CE2 4.05Å; L51-F405 HydrophobicContact CD2-CG 4.46Å; L51-F405 HydrophobicContact CD2-CZ 4.29Å; L59-F405 HydrophobicContact CD1-CE2 3.67Å; L59-F405 HydrophobicContact CD1-CZ 3.69Å; N402-F405 HydrophobicContact CB-CB 4.22Å; N402-F405 HydrophobicContact CB-CD2 3.8Å; N402-F405 WeakPolarHBondContact ND2-CD2 3Å; N402-F405 PolarHBondContact O-N 3.45Å; N402-F405 PolarHBondContact OD1-N 2.94Å; F405-R407 VanDerWaalsContact C-N 3.32Å; F405-R407 PolarHBondContact O-N 2.96Å; F405-S408 PolarHBondContact O-N 2.83Å; F405-S408 VanDerWaalsContact O-N 3.09Å; F405-F409 AromaticContact CD1-CE1 3.92Å; F405-F409 HydrophobicContact CD1-CE1 3.92Å; F405-F409 HydrophobicContact CD1-CZ 4.33Å; F405-F409 WeakPolarHBondContact O-CB 3.37Å; F405-F409 WeakPolarHBondContact O-CD1 3.24Å; F405-F409 PolarHBondContact O-N 3.13Å
406	R	88.7	Confident	83.4	Confident	145 Å²	145	84.6 Å²	84.6	55%	0.547	39%	0.391	S	S	.	.	H	α-helix	trans	-56.5	-43.5	177.8	-173.1	169.2	62.9	164.1	-2	112.8	N402 N403 K410	N402-R406 PolarHBondContact O-N 3.38Å; N403-R406 PolarHBondContact OD1-NH2 2.75Å; R406-K410 WeakPolarHBondContact O-CB 3.28Å; R406-K410 PolarHBondContact O-N 3.39Å
407	R	87.7	Confident	81.5	Confident	186 Å²	186	86.7 Å²	86.7	70%	0.702	40%	0.403	S	S	*	.	H	α-helix	trans	-65.5	-42.7	175.8	-76.5	175.6	179.3	-168.8	-0.5	112.1	N403 F405 K410 K411	N403-R407 WeakPolarHBondContact O-CB 3.3Å; N403-R407 VanDerWaalsContact O-CG 3.3Å; N403-R407 WeakPolarHBondContact O-CG 3.48Å; N403-R407 PolarHBondContact O-N 3.25Å; F405-R407 VanDerWaalsContact C-N 3.32Å; F405-R407 PolarHBondContact O-N 2.96Å; R407-K410 PolarHBondContact O-N 2.81Å; R407-K411 WeakPolarHBondContact O-CB 3.31Å; R407-K411 PolarHBondContact O-N 3.44Å
408	S	87.9	Confident	79.7	Confident	10 Å²	10	92.4 Å²	92.4	7%	0.07	44%	0.439	C	S	.	.	H	α-helix	trans	-65.6	-43.5	179.5	-56.6	0	0	0	0	111	S48 D404 F405 K411 I412	S48-S408 WeakPolarHBondContact CB-OG 3.18Å; S48-S408 PolarHBondContact OG-OG 3Å; S48-S408 VanDerWaalsContact OG-OG 3.07Å; D404-S408 VanDerWaalsContact O-CB 3.32Å; D404-S408 WeakPolarHBondContact O-CB 3.29Å; D404-S408 PolarHBondContact O-N 2.91Å; D404-S408 PolarHBondContact O-OG 3.16Å; F405-S408 PolarHBondContact O-N 2.83Å; F405-S408 VanDerWaalsContact O-N 3.09Å; S408-K411 WeakPolarHBondContact O-CB 3.4Å; S408-K411 PolarHBondContact O-N 2.92Å; S408-K411 VanDerWaalsContact O-N 3.14Å; S408-I412 WeakPolarHBondContact O-CD1 3.15Å; S408-I412 VanDerWaalsContact O-CG1 3.27Å; S408-I412 WeakPolarHBondContact O-CG1 3.25Å; S408-I412 PolarHBondContact O-N 2.94Å
409	F	90	Very high	77.8	Confident	18 Å²	18	102.5 Å²	102.5	8%	0.079	48%	0.477	C	S	.	.	H	α-helix	trans	-62.8	-45	176.1	-76.1	16.6	0	0	0	111.3	L40 V41 A44 T399 F405 K411 I412 L413	L40-F409 HydrophobicContact CB-CD1 4.31Å; L40-F409 HydrophobicContact CB-CE1 3.91Å; L40-F409 HydrophobicContact CB-CE2 4.16Å; L40-F409 HydrophobicContact CB-CZ 3.83Å; L40-F409 HydrophobicContact CD1-CD2 4.4Å; L40-F409 WeakPolarHBondContact O-CE1 3.32Å; V41-F409 HydrophobicContact CG2-CZ 3.79Å; A44-F409 HydrophobicContact CB-CD1 3.83Å; A44-F409 HydrophobicContact CB-CE1 3.6Å; T399-F409 HydrophobicContact CG2-CD2 3.21Å; T399-F409 HydrophobicContact CG2-CE2 3.22Å; T399-F409 HydrophobicContact CG2-CG 4.24Å; T399-F409 HydrophobicContact CG2-CZ 4.27Å; F405-F409 AromaticContact CD1-CE1 3.92Å; F405-F409 HydrophobicContact CD1-CE1 3.92Å; F405-F409 HydrophobicContact CD1-CZ 4.33Å; F405-F409 WeakPolarHBondContact O-CB 3.37Å; F405-F409 WeakPolarHBondContact O-CD1 3.24Å; F405-F409 PolarHBondContact O-N 3.13Å; F409-K411 VanDerWaalsContact C-N 3.26Å; F409-K411 PolarHBondContact O-N 3.25Å; F409-I412 PolarHBondContact O-N 3.3Å; F409-I412 VanDerWaalsContact O-N 3.15Å; F409-L413 WeakPolarHBondContact O-CB 3.4Å; F409-L413 WeakPolarHBondContact O-CG 3.18Å; F409-L413 PolarHBondContact O-N 3.15Å
410	K	88.3	Confident	75.9	Confident	148 Å²	148	111.6 Å²	111.6	64%	0.643	51%	0.507	S	S	*	.	H	α-helix	trans	-59	-38.1	174.3	-171.2	173.6	-176.5	173.1	0	111.9	R406 R407 C414	R406-K410 WeakPolarHBondContact O-CB 3.28Å; R406-K410 PolarHBondContact O-N 3.39Å; R407-K410 PolarHBondContact O-N 2.81Å; K410-C414 HydrophobicContact CG-CB 4.5Å; K410-C414 WeakPolarHBondContact O-CA 3.46Å; K410-C414 WeakPolarHBondContact O-CB 3.47Å; K410-C414 PolarHBondContact O-N 3.36Å
411	K	87.7	Confident	74.1	Confident	162 Å²	162	118.6 Å²	118.6	70%	0.704	53%	0.526	S	S	*	.	H	α-helix	trans	-69.4	-35.8	177.1	-171.6	178.7	-179.8	-177.5	0	112.7	R407 S408 F409	R407-K411 WeakPolarHBondContact O-CB 3.31Å; R407-K411 PolarHBondContact O-N 3.44Å; S408-K411 WeakPolarHBondContact O-CB 3.4Å; S408-K411 PolarHBondContact O-N 2.92Å; S408-K411 VanDerWaalsContact O-N 3.14Å; F409-K411 VanDerWaalsContact C-N 3.26Å; F409-K411 PolarHBondContact O-N 3.25Å
412	I	87.8	Confident	72.2	Confident	49 Å²	49	126.9 Å²	126.9	25%	0.251	58%	0.58	S	S	.	*	H	α-helix	trans	-72	-46.9	178.5	-67	161	0	0	0	110.5	L40 I43 A44 S408 F409	L40-I412 HydrophobicContact CD2-CB 4.49Å; L40-I412 HydrophobicContact CD2-CG2 3.71Å; I43-I412 HydrophobicContact CB-CD1 4.35Å; I43-I412 HydrophobicContact CG2-CD1 3.74Å; I43-I412 HydrophobicContact CG2-CG1 4.26Å; A44-I412 HydrophobicContact CB-CD1 4Å; S408-I412 WeakPolarHBondContact O-CD1 3.15Å; S408-I412 VanDerWaalsContact O-CG1 3.27Å; S408-I412 WeakPolarHBondContact O-CG1 3.25Å; S408-I412 PolarHBondContact O-N 2.94Å; F409-I412 PolarHBondContact O-N 3.3Å; F409-I412 VanDerWaalsContact O-N 3.15Å
413	L	88.4	Confident	71.7	Confident	100 Å²	100	131.2 Å²	131.2	52%	0.524	60%	0.598	S	S	.	*	H	α-helix	trans	-78.1	-43.6	-176.5	-64.6	173.6	0	0	0	112.6	F36 L40 F409 K415	F36-L413 HydrophobicContact CE2-CD2 4.34Å; F36-L413 HydrophobicContact CZ-CD2 3.71Å; L40-L413 HydrophobicContact CD1-CD1 4.31Å; L40-L413 HydrophobicContact CD1-CD2 4.27Å; L40-L413 HydrophobicContact CD2-CD2 4.21Å; F409-L413 WeakPolarHBondContact O-CB 3.4Å; F409-L413 WeakPolarHBondContact O-CG 3.18Å; F409-L413 PolarHBondContact O-N 3.15Å; L413-K415 PolarHBondContact O-N 3.24Å
414	C	86.2	Confident	71.1	Confident	74 Å²	74	135.1 Å²	135.1	50%	0.5	61%	0.613	S	S	.	*	S	Bend	trans	-97	80.8	173.4	-48.9	0	0	0	0	107.7	K410 R416	K410-C414 HydrophobicContact CG-CB 4.5Å; K410-C414 WeakPolarHBondContact O-CA 3.46Å; K410-C414 WeakPolarHBondContact O-CB 3.47Å; K410-C414 PolarHBondContact O-N 3.36Å; C414-R416 PolarHBondContact O-N 2.82Å
415	K	62	Low	70.3	Confident	198 Å²	198	138.8 Å²	138.8	86%	0.861	63%	0.627	S	S	*	*			trans	-55.1	94.5	164.6	-85.5	-173.9	178	176	0	108.1	L413 D417	L413-K415 PolarHBondContact O-N 3.24Å; K415-D417 PolarHBondContact O-N 2.88Å
416	R	50.8	Low	69.3	Low	217 Å²	217	146.9 Å²	146.9	82%	0.819	66%	0.663	S	S	*	*			trans	-83.1	109	166.8	-168.7	166.1	157.4	146.2	-5.8	105.9	C414 T418	C414-R416 PolarHBondContact O-N 2.82Å; R416-T418 PolarHBondContact O-N 3.29Å; R416-T418 PolarHBondContact O-OG1 3.07Å; R416-T418 VanDerWaalsContact O-OG1 3.12Å
417	D	49.1	Very low	68.1	Low	147 Å²	147	147 Å²	147	79%	0.786	67%	0.67	S	S	*	*			trans	-16.4	101.9	168.8	-95.6	-46	0	0	0	112.8	K415	K415-D417 PolarHBondContact O-N 2.88Å
418	T	47.3	Very low	66.8	Low	132 Å²	132	144.4 Å²	144.4	81%	0.81	67%	0.668	S	S	*	*			trans	-110.9	46.7	163.3	-31.8	0	0	0	0	108.5	R416	R416-T418 PolarHBondContact O-N 3.29Å; R416-T418 PolarHBondContact O-OG1 3.07Å; R416-T418 VanDerWaalsContact O-OG1 3.12Å
419	R	45.9	Very low	65.3	Low	229 Å²	229	154 Å²	154	86%	0.864	71%	0.711	S	S	*	*			trans	-108.4	78.3	150.5	-78.7	-168.9	-165.9	171.5	4.7	107.7
420	R	47.8	Very low	63.4	Low	222 Å²	222	164.5 Å²	164.5	84%	0.838	76%	0.76	S	S	*	*			trans	-163.8	97	156	-105.9	-179.2	-151.6	169.6	7	106.1
421	Y	43.6	Very low	61.3	Low	239 Å²	239	165.8 Å²	165.8	94%	0.937	77%	0.769	S	S	*	*			trans	171.4	76.6	142.8	-80.1	-61.4	0	0	0	104.9
422	V	39.2	Very low	58.9	Low	221 Å²	221	166.2 Å²	166.2	100%	1.339	78%	0.775	S	S	*	*			trans	-103.4	0	145.5	177.8	0	0	0	0	104.9

Retrieved 422 of 422 residues in 148.4 ms (Link to these results)

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