A0A087YR23_POEFO Loading...

Probable G-protein coupled receptor 19

G-protein coupled receptor that plays a role in the regulation of circadian rhythms and energy metabolism. Participates in maintaining proper circadian gene expression in the suprachiasmatic nucleus (SCN), the locus of the master circadian clock in the brain. May function as a coordinator of aging-associated metabolic dysfunction, stress response, DNA integrity management, and eventual senescence. Upon binding to adropin, modulates mitochondrial energy metabolism via the p44/42-PDK4 signaling pathway, influencing pyruvate dehydrogenase activity.

AlphaFold DB , UniProt , Accession A0A087YR23, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 333 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	35	Very low	29.2	Very low	237 Å²	237	171.6 Å²	171.6	100%	1.167	85%	0.849	S	S	*	*				0	82.2	0	-126.7	160.9	-179.8	0	0	106.2
2	S	29.4	Very low	29.1	Very low	105 Å²	105	168.9 Å²	168.9	73%	0.734	85%	0.849	S	S	*	*				89.6	101.4	93.5	50.1	0	0	0	0	111.6
3	F	25.9	Very low	29.1	Very low	185 Å²	185	163.8 Å²	163.8	81%	0.811	83%	0.832	S	S	*	*			trans	-22.1	143.3	159.2	-77.9	-99.3	0	0	0	115.9	F5	F3-F5 HydrophobicContact CD1-CD2 4.42Å
4	N	25.9	Very low	29.1	Very low	175 Å²	175	164 Å²	164	94%	0.936	84%	0.835	S	S	*	*			trans	-136.1	127.8	141.9	-124.4	-16	0	0	0	110.8
5	F	30	Very low	29.2	Very low	175 Å²	175	159.1 Å²	159.1	77%	0.768	83%	0.829	S	S	*	*			trans	-123.6	125.1	-173	-143.7	-83	0	0	0	105.6	F3	F3-F5 HydrophobicContact CD1-CD2 4.42Å
6	S	28.2	Very low	29.2	Very low	109 Å²	109	155.6 Å²	155.6	76%	0.762	83%	0.83	S	S	*	*			trans	-176.7	106.6	148.2	-132.3	0	0	0	0	108.9
7	K	31.1	Very low	29.2	Very low	179 Å²	179	156.5 Å²	156.5	78%	0.778	83%	0.834	S	S	*	*				91.1	106.6	75.6	-165.2	-177.1	-167.5	174.4	0	111.6
8	K	28.5	Very low	29.9	Very low	194 Å²	194	153.4 Å²	153.4	84%	0.843	82%	0.824	S	S	*	*				-177.4	111.6	110.6	-99.4	-179.9	179.3	177.7	0	110.2
9	E	32.3	Very low	29.9	Very low	181 Å²	181	153.2 Å²	153.2	85%	0.846	83%	0.829	S	S	*	*			trans	-65.6	148	155.3	-63.2	176.6	140.4	0	0	109.5
10	N	26.1	Very low	30	Very low	173 Å²	173	152.6 Å²	152.6	93%	0.925	83%	0.831	S	S	*	*			trans	-154.3	135.3	130.8	-96.5	-14.7	0	0	0	109.9
11	F	28.3	Very low	30	Very low	175 Å²	175	149.6 Å²	149.6	77%	0.768	83%	0.827	S	S	*	*			trans	-100.5	129.8	-167	-162.5	-89.9	0	0	0	108.5	V13	F11-V13 HydrophobicContact CD1-CG2 4.31Å; F11-V13 HydrophobicContact CE1-CB 4.38Å; F11-V13 HydrophobicContact CE1-CG2 3.6Å; F11-V13 HydrophobicContact CZ-CG2 3.93Å
12	T	27.9	Very low	29.8	Very low	139 Å²	139	145.5 Å²	145.5	85%	0.853	81%	0.809	S	S	*	*			trans	-151.3	105.9	148.4	-15.2	0	0	0	0	111
13	V	29.6	Very low	29.6	Very low	102 Å²	102	149.6 Å²	149.6	62%	0.618	81%	0.809	S	S	*	*			trans	-68.2	133.6	161	168.7	0	0	0	0	108.5	F11	F11-V13 HydrophobicContact CD1-CG2 4.31Å; F11-V13 HydrophobicContact CE1-CB 4.38Å; F11-V13 HydrophobicContact CE1-CG2 3.6Å; F11-V13 HydrophobicContact CZ-CG2 3.93Å
14	L	28.5	Very low	29.7	Very low	167 Å²	167	146.4 Å²	146.4	87%	0.874	81%	0.81	S	S	*	*			trans	-158.3	113	147.3	-110	148.3	0	0	0	110.7
15	A	31.7	Very low	30.1	Very low	90 Å²	90	145.4 Å²	145.4	74%	0.744	80%	0.804	S	S	*	*			trans	-73.1	144.3	170.5	0	0	0	0	0	111
16	A	29.5	Very low	30.1	Very low	104 Å²	104	146.3 Å²	146.3	86%	0.86	81%	0.81	S	S	*	*			trans	-178.1	115.4	142.9	0	0	0	0	0	111.5
17	L	28	Very low	30.4	Very low	170 Å²	170	145 Å²	145	89%	0.89	81%	0.814	S	S	*	*			trans	-97.7	174.4	145.9	-95.8	138.6	0	0	0	106.7
18	P	42.4	Very low	30.4	Very low	102 Å²	102	141.5 Å²	141.5	66%	0.662	81%	0.812	S	S	*	*			cis	-131.3	168	-27.2	34.3	-17.8	0	0	0	112.2
19	T	30.8	Very low	31.1	Very low	149 Å²	149	139.5 Å²	139.5	91%	0.914	82%	0.816	S	S	*	*			trans	-156	130.3	154.5	11.3	0	0	0	0	113.1
20	T	31.8	Very low	31.2	Very low	141 Å²	141	136.1 Å²	136.1	87%	0.865	81%	0.81	S	S	*	*			trans	-86.2	139.9	174.9	42.3	0	0	0	0	112.7
21	A	30.1	Very low	31.6	Very low	90 Å²	90	139.2 Å²	139.2	74%	0.744	81%	0.809	S	S	*	*			trans	-177.3	108.4	145.9	0	0	0	0	0	108.2
22	L	29.6	Very low	32	Very low	150 Å²	150	139.3 Å²	139.3	79%	0.785	81%	0.812	S	S	*	*				86.4	124.1	82.6	-96.1	159	0	0	0	114.9
23	Y	26.3	Very low	32.6	Very low	191 Å²	191	138.5 Å²	138.5	75%	0.749	81%	0.809	S	S	*	*			trans	71.8	114.8	160.5	-78.6	-78.2	0	0	0	119.8
24	S	26.1	Very low	32.7	Very low	118 Å²	118	140.1 Å²	140.1	83%	0.825	81%	0.814	S	S	*	*				-166.4	119.9	112.6	-70.4	0	0	0	0	109.8
25	L	35.5	Very low	33.4	Very low	155 Å²	155	137.1 Å²	137.1	81%	0.812	81%	0.813	S	S	*	*			trans	-65.5	129.3	160.8	-91.5	102	0	0	0	108.5
26	E	30.1	Very low	33.7	Very low	193 Å²	193	138.7 Å²	138.7	90%	0.902	81%	0.814	S	S	*	*			trans	-162	144	141.7	-116.7	168.4	154.8	0	0	111.2
27	G	34	Very low	34.4	Very low	81 Å²	81	137.8 Å²	137.8	84%	0.835	81%	0.807	S	S	*	*			trans	-69.6	141.8	-156.9	0	0	0	0	0	115.2
28	S	31.2	Very low	35.1	Very low	107 Å²	107	134.9 Å²	134.9	75%	0.748	80%	0.796	S	S	*	*			trans	-154.6	106.9	149.2	41.5	0	0	0	0	108.2	P30	S28-P30 WeakPolarHBondContact O-CD 3.37Å
29	T	42.4	Very low	35.2	Very low	151 Å²	151	135.7 Å²	135.7	93%	0.926	80%	0.804	S	S	*	*			trans	-80.9	115.1	157.6	14.6	0	0	0	0	107.7
30	P	35.8	Very low	36.3	Very low	110 Å²	110	130.3 Å²	130.3	71%	0.714	78%	0.778	S	S	*	*			trans	-111.2	120.9	146	27.4	-15.1	0	0	0	108.7	S28	S28-P30 WeakPolarHBondContact O-CD 3.37Å
31	R	33.5	Very low	37.8	Very low	239 Å²	239	128.8 Å²	128.8	90%	0.902	77%	0.765	S	S	*	*			trans	13.9	112.7	154.3	-84.6	171.2	171.2	154	-1.7	115.5	P33	R31-P33 WeakPolarHBondContact O-CD 3.5Å
32	Q	37.8	Very low	39.5	Very low	177 Å²	177	126.2 Å²	126.2	83%	0.827	74%	0.738	S	S	*	*			trans	-48	124.5	148.2	-75.3	-175.9	-18	0	0	108.1	N34	Q32-N34 PolarHBondContact O-N 3.29Å
33	P	39.5	Very low	41.8	Very low	121 Å²	121	122.3 Å²	122.3	79%	0.786	72%	0.724	S	S	*	*			trans	-65.9	118.2	154.2	25.6	-21.3	0	0	0	104.7	R31 A35	R31-P33 WeakPolarHBondContact O-CD 3.5Å; P33-A35 PolarHBondContact O-N 3.35Å
34	N	31.7	Very low	44.2	Very low	137 Å²	137	118.2 Å²	118.2	73%	0.733	72%	0.723	S	S	*	*			trans	-35.3	120.8	161.4	-77.9	-23.6	0	0	0	107.7	Q32 T36	Q32-N34 PolarHBondContact O-N 3.29Å; N34-T36 PolarHBondContact O-N 2.97Å
35	A	43	Very low	46.7	Very low	104 Å²	104	114.5 Å²	114.5	86%	0.86	70%	0.703	S	S	*	*			trans	-61.7	84.2	159.7	0	0	0	0	0	106	P33 A37	P33-A35 PolarHBondContact O-N 3.35Å; A35-A37 VanDerWaalsContact C-N 3.33Å; A35-A37 PolarHBondContact O-N 3.35Å
36	T	39.3	Very low	48.5	Very low	122 Å²	122	110.6 Å²	110.6	75%	0.748	68%	0.681	S	S	*	*			trans	-55.2	107.5	160.7	27.7	0	0	0	0	104.9	N34 T38	N34-T36 PolarHBondContact O-N 2.97Å; T36-T38 PolarHBondContact O-N 3.43Å
37	A	43	Very low	50.6	Low	86 Å²	86	105 Å²	105	71%	0.711	66%	0.659	S	S	*	*			trans	-36.3	127.6	164.8	0	0	0	0	0	108.7	A35 S39	A35-A37 VanDerWaalsContact C-N 3.33Å; A35-A37 PolarHBondContact O-N 3.35Å; A37-S39 PolarHBondContact O-N 3.23Å
38	T	43.7	Very low	52.8	Low	109 Å²	109	103.6 Å²	103.6	67%	0.669	64%	0.64	S	S	*	*			trans	-52.7	100.5	175.1	30.8	0	0	0	0	108.5	T36 G40 D41	T36-T38 PolarHBondContact O-N 3.43Å; T38-G40 PolarHBondContact O-N 3.15Å; T38-D41 PolarHBondContact OG1-OD2 3.34Å
39	S	44.6	Very low	55.2	Low	118 Å²	118	103.8 Å²	103.8	83%	0.825	63%	0.632	S	S	*	*	T	Hydrogen-bonded Turn	trans	-77.3	26.8	-176.5	38.1	0	0	0	0	112.3	A37	A37-S39 PolarHBondContact O-N 3.23Å
40	G	54.2	Low	56.8	Low	37 Å²	37	98.5 Å²	98.5	38%	0.381	60%	0.597	S	S	.	*	T	Hydrogen-bonded Turn	trans	-124.2	-17.8	-174.4	0	0	0	0	0	114.9	T38 R289	T38-G40 PolarHBondContact O-N 3.15Å; G40-R289 WeakPolarHBondContact O-CB 3.46Å; G40-R289 WeakPolarHBondContact O-CD 3.48Å
41	D	61.4	Low	58.8	Low	109 Å²	109	94.8 Å²	94.8	58%	0.583	58%	0.579	S	S	*	*	S	Bend	trans	-90.3	143.3	-175.8	-58.9	-39.1	0	0	0	111.2	T38 R289	T38-D41 PolarHBondContact OG1-OD2 3.34Å; D41-R289 PolarHBondContact O-NH1 2.02Å
42	L	66	Low	61.3	Low	35 Å²	35	89.7 Å²	89.7	18%	0.183	57%	0.569	C	S	.	*	P	Polyproline II helix	trans	-64.3	140	171	-80.9	84.1	0	0	0	109.2	V47 L50 R289 L292 L293	L42-V47 HydrophobicContact CB-CG2 3.57Å; L42-V47 HydrophobicContact CD2-CG2 4.15Å; L42-L50 HydrophobicContact CD2-CD1 3.48Å; L42-L50 VanDerWaalsContact CD2-CD1 3.48Å; L42-R289 HydrophobicContact CD1-CG 4.28Å; L42-L292 HydrophobicContact CD1-CD2 3.78Å; L42-L293 HydrophobicContact CD2-CD2 3.7Å; L42-L293 HydrophobicContact CG-CD2 4.2Å
43	S	78.7	Confident	63.5	Low	69 Å²	69	84.3 Å²	84.3	48%	0.483	55%	0.548	S	S	.	.	P	Polyproline II helix	trans	-62.4	142.5	173.3	175.2	0	0	0	0	110.1	G45 E46 V47	S43-G45 PolarHBondContact O-N 3.26Å; S43-E46 WeakPolarHBondContact CB-OE2 3.36Å; S43-E46 PolarHBondContact N-OE2 3.07Å; S43-E46 WeakPolarHBondContact O-CA 3.28Å; S43-E46 WeakPolarHBondContact O-CB 3.4Å; S43-E46 PolarHBondContact O-N 2.91Å; S43-V47 PolarHBondContact O-N 3.05Å
44	S	76.1	Confident	65.5	Low	105 Å²	105	79.1 Å²	79.1	73%	0.734	51%	0.513	S	S	*	.	H	α-helix	trans	-53.9	-32	177.6	-48.3	0	0	0	0	112.7	A48	S44-A48 WeakPolarHBondContact O-CB 3.39Å; S44-A48 PolarHBondContact O-N 3.47Å
45	G	78.8	Confident	68.1	Low	39 Å²	39	73.9 Å²	73.9	40%	0.402	49%	0.491	S	S	.	.	H	α-helix	trans	-70.3	-38.6	174.6	0	0	0	0	0	113.5	S43 A48 I49	S43-G45 PolarHBondContact O-N 3.26Å; G45-A48 PolarHBondContact O-N 2.97Å; G45-I49 VanDerWaalsContact O-CG1 3.31Å; G45-I49 WeakPolarHBondContact O-CG1 3.4Å; G45-I49 PolarHBondContact O-N 2.98Å
46	E	74.4	Confident	70.3	Confident	74 Å²	74	75.2 Å²	75.2	35%	0.346	48%	0.478	S	S	.	.	H	α-helix	trans	-63.9	-49.7	173.9	-66.1	172.2	127	0	0	109.5	S43 A48 I49 L50 R289	S43-E46 WeakPolarHBondContact CB-OE2 3.36Å; S43-E46 PolarHBondContact N-OE2 3.07Å; S43-E46 WeakPolarHBondContact O-CA 3.28Å; S43-E46 WeakPolarHBondContact O-CB 3.4Å; S43-E46 PolarHBondContact O-N 2.91Å; E46-A48 VanDerWaalsContact C-N 3.29Å; E46-A48 PolarHBondContact O-N 2.97Å; E46-I49 PolarHBondContact O-N 3.23Å; E46-L50 VanDerWaalsContact O-CB 3.28Å; E46-L50 WeakPolarHBondContact O-CB 3.29Å; E46-L50 WeakPolarHBondContact O-CG 3.33Å; E46-L50 PolarHBondContact O-N 3.39Å; E46-R289 IonicContact OE1-NH2 3.04Å; E46-R289 PolarHBondContact OE1-NH2 2.77Å; E46-R289 IonicContact OE2-CZ 2.79Å; E46-R289 IonicContact OE2-NH2 3.93Å; E46-R289 PolarHBondContact OE2-NH2 2.86Å
47	V	74.2	Confident	72.8	Confident	74 Å²	74	71.1 Å²	71.1	45%	0.448	45%	0.451	S	S	.	.	H	α-helix	trans	-58.4	-40.8	177.7	-179.8	0	0	0	0	111.7	L42 S43 L50 G51	L42-V47 HydrophobicContact CB-CG2 3.57Å; L42-V47 HydrophobicContact CD2-CG2 4.15Å; S43-V47 PolarHBondContact O-N 3.05Å; V47-L50 PolarHBondContact O-N 3.43Å; V47-G51 PolarHBondContact O-N 2.94Å
48	A	79.8	Confident	75.1	Confident	52 Å²	52	70.7 Å²	70.7	43%	0.43	43%	0.431	S	S	.	.	H	α-helix	trans	-65	-47.8	178.1	0	0	0	0	0	112.5	S44 G45 E46 L50 G51 L52	S44-A48 WeakPolarHBondContact O-CB 3.39Å; S44-A48 PolarHBondContact O-N 3.47Å; G45-A48 PolarHBondContact O-N 2.97Å; E46-A48 VanDerWaalsContact C-N 3.29Å; E46-A48 PolarHBondContact O-N 2.97Å; A48-L50 VanDerWaalsContact C-N 3.3Å; A48-L50 PolarHBondContact O-N 3.07Å; A48-G51 PolarHBondContact O-N 3.2Å; A48-L52 WeakPolarHBondContact O-CB 3.48Å; A48-L52 VanDerWaalsContact O-CG 3.27Å; A48-L52 WeakPolarHBondContact O-CG 3.08Å; A48-L52 PolarHBondContact O-N 3.2Å
49	I	81.3	Confident	77.4	Confident	112 Å²	112	69.8 Å²	69.8	57%	0.574	42%	0.422	S	S	*	.	H	α-helix	trans	-61.6	-43.8	176.2	-67.5	166.9	0	0	0	109.9	G45 E46 L52 V53	G45-I49 VanDerWaalsContact O-CG1 3.31Å; G45-I49 WeakPolarHBondContact O-CG1 3.4Å; G45-I49 PolarHBondContact O-N 2.98Å; E46-I49 PolarHBondContact O-N 3.23Å; I49-L52 PolarHBondContact O-N 3.23Å; I49-V53 HydrophobicContact CG2-CG2 4.5Å; I49-V53 WeakPolarHBondContact O-CG2 3.42Å; I49-V53 PolarHBondContact O-N 3.08Å
50	L	75.9	Confident	79.6	Confident	39 Å²	39	66.5 Å²	66.5	20%	0.204	40%	0.397	C	S	.	.	H	α-helix	trans	-60.6	-49.2	178.6	-65.9	171.5	0	0	0	111.4	L42 E46 V47 A48 L52 F54 L293 W300	L42-L50 HydrophobicContact CD2-CD1 3.48Å; L42-L50 VanDerWaalsContact CD2-CD1 3.48Å; E46-L50 VanDerWaalsContact O-CB 3.28Å; E46-L50 WeakPolarHBondContact O-CB 3.29Å; E46-L50 WeakPolarHBondContact O-CG 3.33Å; E46-L50 PolarHBondContact O-N 3.39Å; V47-L50 PolarHBondContact O-N 3.43Å; A48-L50 VanDerWaalsContact C-N 3.3Å; A48-L50 PolarHBondContact O-N 3.07Å; L50-L52 PolarHBondContact O-N 2.98Å; L50-F54 WeakPolarHBondContact O-CB 3.34Å; L50-F54 PolarHBondContact O-N 3.47Å; L50-L293 HydrophobicContact CD1-CD2 4.48Å; L50-W300 VanDerWaalsContact CA-CH2 3.47Å; L50-W300 HydrophobicContact CB-CH2 3.82Å; L50-W300 HydrophobicContact CB-CZ2 3.47Å; L50-W300 VanDerWaalsContact CB-CZ2 3.47Å; L50-W300 HydrophobicContact CD2-CH2 3.01Å; L50-W300 HydrophobicContact CD2-CZ2 3.31Å; L50-W300 HydrophobicContact CD2-CZ3 3.67Å; L50-W300 HydrophobicContact CG-CH2 3.89Å; L50-W300 HydrophobicContact CG-CZ2 3.9Å; L50-W300 WeakPolarHBondContact O-CZ2 3.36Å
51	G	78.5	Confident	81.6	Confident	32 Å²	32	64.8 Å²	64.8	33%	0.33	38%	0.379	S	S	.	.	H	α-helix	trans	-60.1	-41.6	177	0	0	0	0	0	113.2	V47 A48 G55	V47-G51 PolarHBondContact O-N 2.94Å; A48-G51 PolarHBondContact O-N 3.2Å; G51-G55 WeakPolarHBondContact O-CA 3.48Å; G51-G55 PolarHBondContact O-N 3.13Å
52	L	85.6	Confident	83.2	Confident	132 Å²	132	61.1 Å²	61.1	69%	0.691	36%	0.359	S	S	*	.	H	α-helix	trans	-67	-46.5	-179.7	-74.4	168.3	0	0	0	112.6	A48 I49 L50 G55 F56	A48-L52 WeakPolarHBondContact O-CB 3.48Å; A48-L52 VanDerWaalsContact O-CG 3.27Å; A48-L52 WeakPolarHBondContact O-CG 3.08Å; A48-L52 PolarHBondContact O-N 3.2Å; I49-L52 PolarHBondContact O-N 3.23Å; L50-L52 PolarHBondContact O-N 2.98Å; L52-G55 PolarHBondContact O-N 2.69Å; L52-F56 WeakPolarHBondContact O-CB 3.14Å; L52-F56 PolarHBondContact O-N 2.9Å
53	V	83.4	Confident	84.6	Confident	64 Å²	64	65.2 Å²	65.2	39%	0.388	38%	0.38	S	S	.	.	H	α-helix	trans	-63.6	-46.8	178.9	172.7	0	0	0	0	110.5	I49 F56 L57 W300	I49-V53 HydrophobicContact CG2-CG2 4.5Å; I49-V53 WeakPolarHBondContact O-CG2 3.42Å; I49-V53 PolarHBondContact O-N 3.08Å; V53-F56 PolarHBondContact O-N 3.38Å; V53-L57 HydrophobicContact CG1-CD1 4.35Å; V53-L57 WeakPolarHBondContact O-CG 3.49Å; V53-L57 PolarHBondContact O-N 3.35Å; V53-W300 HydrophobicContact CB-CH2 4.06Å; V53-W300 HydrophobicContact CG1-CH2 4.24Å; V53-W300 HydrophobicContact CG1-CZ3 4.26Å
54	F	82.7	Confident	85.3	Confident	13 Å²	13	62.5 Å²	62.5	6%	0.057	36%	0.364	C	S	.	.	H	α-helix	trans	-64.1	-43.7	178.1	-174.8	-99	0	0	0	111.7	L50 F56 L57 W58 A101 L105 W300 F303	L50-F54 WeakPolarHBondContact O-CB 3.34Å; L50-F54 PolarHBondContact O-N 3.47Å; F54-F56 VanDerWaalsContact C-N 3.32Å; F54-F56 PolarHBondContact O-N 3.02Å; F54-L57 PolarHBondContact O-N 2.88Å; F54-W58 WeakPolarHBondContact O-CB 3.42Å; F54-W58 PolarHBondContact O-N 3.23Å; F54-A101 HydrophobicContact CZ-CB 4.15Å; F54-L105 HydrophobicContact CD1-CD1 4.31Å; F54-L105 HydrophobicContact CD1-CD2 3.81Å; F54-L105 HydrophobicContact CD1-CG 4.48Å; F54-L105 HydrophobicContact CE1-CB 4.15Å; F54-L105 HydrophobicContact CE1-CD2 3.94Å; F54-L105 HydrophobicContact CE1-CG 4.47Å; F54-W300 HydrophobicContact CB-CZ2 4.43Å; F54-W300 AromaticContact CD2-CD1 3.53Å; F54-W300 AromaticContact CD2-NE1 3.64Å; F54-F303 HydrophobicContact CE2-CB 4.37Å; F54-F303 HydrophobicContact CE2-CD2 4.25Å; F54-F303 HydrophobicContact CE2-CG 4.15Å; F54-F303 HydrophobicContact CZ-CD2 4.46Å
55	G	86.4	Confident	86.3	Confident	26 Å²	26	57.5 Å²	57.5	27%	0.268	33%	0.329	S	S	.	.	H	α-helix	trans	-59	-41.6	176.5	0	0	0	0	0	112.5	G51 L52 W58 L59	G51-G55 WeakPolarHBondContact O-CA 3.48Å; G51-G55 PolarHBondContact O-N 3.13Å; L52-G55 PolarHBondContact O-N 2.69Å; G55-W58 PolarHBondContact O-N 3.05Å; G55-L59 WeakPolarHBondContact O-CG 3.3Å; G55-L59 PolarHBondContact O-N 2.88Å
56	F	89.3	Confident	87.1	Confident	133 Å²	133	57.7 Å²	57.7	58%	0.583	33%	0.326	S	S	*	.	H	α-helix	trans	-63	-49.9	174.3	176	-100.8	0	0	0	112.1	L52 V53 F54 W58 L59 V60	L52-F56 WeakPolarHBondContact O-CB 3.14Å; L52-F56 PolarHBondContact O-N 2.9Å; V53-F56 PolarHBondContact O-N 3.38Å; F54-F56 VanDerWaalsContact C-N 3.32Å; F54-F56 PolarHBondContact O-N 3.02Å; F56-W58 VanDerWaalsContact C-N 3.27Å; F56-W58 PolarHBondContact O-N 3.06Å; F56-L59 PolarHBondContact O-N 3.07Å; F56-V60 HydrophobicContact CD1-CG2 4.36Å; F56-V60 HydrophobicContact CD2-CG2 4.43Å; F56-V60 HydrophobicContact CE1-CG2 3.92Å; F56-V60 HydrophobicContact CE2-CG2 4Å; F56-V60 HydrophobicContact CZ-CG2 3.72Å; F56-V60 WeakPolarHBondContact O-CG2 3.35Å; F56-V60 PolarHBondContact O-N 3.48Å
57	L	89.9	Confident	88	Confident	35 Å²	35	56.5 Å²	56.5	18%	0.183	32%	0.322	C	S	.	.	H	α-helix	trans	-59.8	-40	177.5	-69.6	175.3	0	0	0	111.7	V53 F54 V60 S61 F303 A307	V53-L57 HydrophobicContact CG1-CD1 4.35Å; V53-L57 WeakPolarHBondContact O-CG 3.49Å; V53-L57 PolarHBondContact O-N 3.35Å; F54-L57 PolarHBondContact O-N 2.88Å; L57-V60 PolarHBondContact O-N 3.42Å; L57-S61 VanDerWaalsContact O-CB 3.31Å; L57-S61 WeakPolarHBondContact O-CB 3.35Å; L57-S61 PolarHBondContact O-N 3.24Å; L57-F303 HydrophobicContact CB-CD1 4Å; L57-F303 HydrophobicContact CB-CE1 4.48Å; L57-A307 HydrophobicContact CD2-CB 4.22Å
58	W	91.3	Very high	88.9	Confident	78 Å²	78	53 Å²	53	30%	0.295	30%	0.301	S	S	.	.	H	α-helix	trans	-59.8	-48.8	175.8	-176.4	80.8	0	0	0	112.5	F54 G55 F56 S61 I62 S97 F303	F54-W58 WeakPolarHBondContact O-CB 3.42Å; F54-W58 PolarHBondContact O-N 3.23Å; G55-W58 PolarHBondContact O-N 3.05Å; F56-W58 VanDerWaalsContact C-N 3.27Å; F56-W58 PolarHBondContact O-N 3.06Å; W58-S61 WeakPolarHBondContact O-CB 3.42Å; W58-S61 PolarHBondContact O-N 3.4Å; W58-I62 HydrophobicContact CD2-CD1 3.74Å; W58-I62 HydrophobicContact CE3-CD1 4.17Å; W58-I62 HydrophobicContact CG-CD1 4.4Å; W58-I62 HydrophobicContact CH2-CD1 3.68Å; W58-I62 HydrophobicContact CZ2-CD1 3.19Å; W58-I62 HydrophobicContact CZ3-CD1 4.14Å; W58-I62 PolarHBondContact O-N 3.21Å; W58-S97 PolarHBondContact NE1-O 3.49Å; W58-F303 VanDerWaalsContact CA-CE1 3.42Å; W58-F303 HydrophobicContact CB-CE1 4.16Å; W58-F303 HydrophobicContact CB-CZ 4.3Å; W58-F303 AromaticContact CD1-CZ 3.74Å; W58-F303 HydrophobicContact CG-CZ 4.39Å
59	L	92.1	Very high	89.5	Confident	89 Å²	89	51.8 Å²	51.8	47%	0.466	29%	0.289	S	S	.	.	H	α-helix	trans	-61.4	-46.9	175.6	-73	173.6	0	0	0	111.9	G55 F56 S61 I62 L63	G55-L59 WeakPolarHBondContact O-CG 3.3Å; G55-L59 PolarHBondContact O-N 2.88Å; F56-L59 PolarHBondContact O-N 3.07Å; L59-S61 VanDerWaalsContact C-N 3.28Å; L59-S61 PolarHBondContact O-N 3.36Å; L59-I62 PolarHBondContact O-N 3.28Å; L59-L63 WeakPolarHBondContact O-CB 3.23Å; L59-L63 VanDerWaalsContact O-CG 3.28Å; L59-L63 WeakPolarHBondContact O-CG 3.36Å; L59-L63 PolarHBondContact O-N 3.42Å
60	V	92.6	Very high	90	Very high	50 Å²	50	50.7 Å²	50.7	30%	0.303	28%	0.284	S	S	.	.	H	α-helix	trans	-59.9	-42.1	177.5	172.7	0	0	0	0	110.8	F56 L57 G64 A307	F56-V60 HydrophobicContact CD1-CG2 4.36Å; F56-V60 HydrophobicContact CD2-CG2 4.43Å; F56-V60 HydrophobicContact CE1-CG2 3.92Å; F56-V60 HydrophobicContact CE2-CG2 4Å; F56-V60 HydrophobicContact CZ-CG2 3.72Å; F56-V60 WeakPolarHBondContact O-CG2 3.35Å; F56-V60 PolarHBondContact O-N 3.48Å; L57-V60 PolarHBondContact O-N 3.42Å; V60-G64 WeakPolarHBondContact O-CA 3.36Å; V60-G64 PolarHBondContact O-N 3.3Å; V60-A307 HydrophobicContact CB-CB 4.35Å; V60-A307 HydrophobicContact CG1-CB 4.02Å
61	S	94.2	Very high	90.7	Very high	0 Å²	0	48.8 Å²	48.8	0%	0	27%	0.274	C	S	.	.	H	α-helix	trans	-62.4	-50.1	178.4	-178.6	0	0	0	0	112.2	L57 W58 L59 N65 S97 F303 T306	L57-S61 VanDerWaalsContact O-CB 3.31Å; L57-S61 WeakPolarHBondContact O-CB 3.35Å; L57-S61 PolarHBondContact O-N 3.24Å; W58-S61 WeakPolarHBondContact O-CB 3.42Å; W58-S61 PolarHBondContact O-N 3.4Å; L59-S61 VanDerWaalsContact C-N 3.28Å; L59-S61 PolarHBondContact O-N 3.36Å; S61-N65 VanDerWaalsContact O-CB 3.27Å; S61-N65 WeakPolarHBondContact O-CB 3.37Å; S61-N65 PolarHBondContact O-N 2.97Å; S61-N65 PolarHBondContact O-ND2 3.41Å; S61-N65 PolarHBondContact OG-ND2 3.44Å; S61-S97 PolarHBondContact OG-OG 3.28Å; S61-F303 VanDerWaalsContact CB-CE1 3.48Å; S61-T306 WeakPolarHBondContact OG-CG2 3.36Å
62	I	95.3	Very high	91.2	Very high	32 Å²	32	47.8 Å²	47.8	16%	0.164	26%	0.261	C	S	.	.	H	α-helix	trans	-64.5	-54.6	-179.2	-70.4	174.1	0	0	0	110.6	W58 L59 G64 A66 L94 L98	W58-I62 HydrophobicContact CD2-CD1 3.74Å; W58-I62 HydrophobicContact CE3-CD1 4.17Å; W58-I62 HydrophobicContact CG-CD1 4.4Å; W58-I62 HydrophobicContact CH2-CD1 3.68Å; W58-I62 HydrophobicContact CZ2-CD1 3.19Å; W58-I62 HydrophobicContact CZ3-CD1 4.14Å; W58-I62 PolarHBondContact O-N 3.21Å; L59-I62 PolarHBondContact O-N 3.28Å; I62-G64 VanDerWaalsContact C-N 3.33Å; I62-G64 PolarHBondContact O-N 2.95Å; I62-A66 WeakPolarHBondContact O-CB 3.5Å; I62-A66 PolarHBondContact O-N 3.45Å; I62-L94 HydrophobicContact CG2-CD2 4.48Å; I62-L98 HydrophobicContact CD1-CD2 3.61Å; I62-L98 HydrophobicContact CD1-CG 4.43Å; I62-L98 HydrophobicContact CG1-CD2 4.31Å
63	L	95.5	Very high	91.1	Very high	121 Å²	121	49.3 Å²	49.3	63%	0.634	26%	0.264	S	S	*	.	H	α-helix	trans	-62.9	-43.5	-176	-65.1	175.5	0	0	0	111	L59 L67	L59-L63 WeakPolarHBondContact O-CB 3.23Å; L59-L63 VanDerWaalsContact O-CG 3.28Å; L59-L63 WeakPolarHBondContact O-CG 3.36Å; L59-L63 PolarHBondContact O-N 3.42Å; L63-L67 VanDerWaalsContact O-CB 3.24Å; L63-L67 WeakPolarHBondContact O-CB 3.39Å; L63-L67 PolarHBondContact O-N 3.16Å
64	G	94.7	Very high	91.2	Very high	13 Å²	13	53 Å²	53	13%	0.134	27%	0.271	C	S	.	.	H	α-helix	trans	-67.4	-47	-179	0	0	0	0	0	112.9	V60 I62 L67 V68	V60-G64 WeakPolarHBondContact O-CA 3.36Å; V60-G64 PolarHBondContact O-N 3.3Å; I62-G64 VanDerWaalsContact C-N 3.33Å; I62-G64 PolarHBondContact O-N 2.95Å; G64-L67 WeakPolarHBondContact O-CB 3.28Å; G64-L67 PolarHBondContact O-N 2.84Å; G64-V68 WeakPolarHBondContact O-CG2 3.39Å; G64-V68 PolarHBondContact O-N 3.33Å
65	N	95.8	Very high	91	Very high	0 Å²	0	52.6 Å²	52.6	0%	0	27%	0.269	C	S	.	.	H	α-helix	trans	-72.8	-33.6	179.6	-70.9	-63.5	0	0	0	112.3	S61 L67 V68 C69 A90 D93 L94 T306	S61-N65 VanDerWaalsContact O-CB 3.27Å; S61-N65 WeakPolarHBondContact O-CB 3.37Å; S61-N65 PolarHBondContact O-N 2.97Å; S61-N65 PolarHBondContact O-ND2 3.41Å; S61-N65 PolarHBondContact OG-ND2 3.44Å; N65-L67 VanDerWaalsContact C-N 3.34Å; N65-V68 WeakPolarHBondContact O-CB 3.25Å; N65-V68 PolarHBondContact O-N 3.46Å; N65-C69 PolarHBondContact O-N 3Å; N65-C69 VanDerWaalsContact O-N 3.08Å; N65-C69 PolarHBondContact O-SG 3.22Å; N65-A90 HydrophobicContact CB-CB 4.13Å; N65-D93 HydrophobicContact CB-CB 4.3Å; N65-D93 PolarHBondContact OD1-OD2 3.42Å; N65-L94 HydrophobicContact CB-CD2 4.03Å; N65-L94 HydrophobicContact CB-CG 3.9Å; N65-T306 PolarHBondContact ND2-O 3.43Å
66	A	95.9	Very high	89.9	Confident	43 Å²	43	62.3 Å²	62.3	36%	0.355	30%	0.298	S	S	.	.	H	α-helix	trans	-62.3	-42.5	170.4	0	0	0	0	0	111.5	I62 V68 C69 L70 L94	I62-A66 WeakPolarHBondContact O-CB 3.5Å; I62-A66 PolarHBondContact O-N 3.45Å; A66-V68 VanDerWaalsContact C-N 3.32Å; A66-V68 PolarHBondContact O-N 2.93Å; A66-C69 PolarHBondContact O-N 3.49Å; A66-L70 WeakPolarHBondContact O-CB 3.33Å; A66-L70 PolarHBondContact O-N 2.88Å; A66-L94 HydrophobicContact CB-CD2 4.38Å
67	L	93.1	Very high	88.7	Confident	49 Å²	49	64.5 Å²	64.5	26%	0.257	30%	0.303	S	S	.	.	H	α-helix	trans	-61.7	-40.3	174.5	-179.3	63	0	0	0	111.8	L63 G64 N65 C69 L70 V71 M324 F328	L63-L67 VanDerWaalsContact O-CB 3.24Å; L63-L67 WeakPolarHBondContact O-CB 3.39Å; L63-L67 PolarHBondContact O-N 3.16Å; G64-L67 WeakPolarHBondContact O-CB 3.28Å; G64-L67 PolarHBondContact O-N 2.84Å; N65-L67 VanDerWaalsContact C-N 3.34Å; L67-C69 PolarHBondContact O-N 2.84Å; L67-L70 PolarHBondContact O-N 3.36Å; L67-V71 HydrophobicContact CD1-CG2 3.73Å; L67-V71 HydrophobicContact CG-CG2 4.08Å; L67-V71 WeakPolarHBondContact O-CB 3.3Å; L67-V71 VanDerWaalsContact O-CG2 3.23Å; L67-V71 WeakPolarHBondContact O-CG2 3.38Å; L67-V71 PolarHBondContact O-N 2.98Å; L67-M324 HydrophobicContact CD2-SD 4.46Å; L67-F328 HydrophobicContact CD1-CE2 3.84Å; L67-F328 HydrophobicContact CD1-CZ 3.59Å; L67-F328 HydrophobicContact CD2-CE2 4.25Å; L67-F328 HydrophobicContact CD2-CZ 4.24Å
68	V	93.2	Very high	87.4	Confident	0 Å²	0	63 Å²	63	0%	0	29%	0.294	C	S	.	.	H	α-helix	trans	-56.8	-49.3	174.3	170.7	0	0	0	0	111.3	G64 N65 A66 I72 V86 A90 P310 Y313 F320	G64-V68 WeakPolarHBondContact O-CG2 3.39Å; G64-V68 PolarHBondContact O-N 3.33Å; N65-V68 WeakPolarHBondContact O-CB 3.25Å; N65-V68 PolarHBondContact O-N 3.46Å; A66-V68 VanDerWaalsContact C-N 3.32Å; A66-V68 PolarHBondContact O-N 2.93Å; V68-I72 HydrophobicContact CG1-CD1 3.92Å; V68-I72 WeakPolarHBondContact O-CG1 3.07Å; V68-I72 PolarHBondContact O-N 2.67Å; V68-V86 HydrophobicContact CG1-CG1 3.6Å; V68-A90 HydrophobicContact CB-CB 4.13Å; V68-A90 HydrophobicContact CG1-CB 3.84Å; V68-P310 HydrophobicContact CG2-CB 4.13Å; V68-P310 HydrophobicContact CG2-CG 4.33Å; V68-Y313 HydrophobicContact CG1-CD2 4.31Å; V68-Y313 HydrophobicContact CG1-CE2 4.44Å; V68-Y313 HydrophobicContact CG2-CD2 3.84Å; V68-Y313 HydrophobicContact CG2-CE2 4.44Å; V68-F320 HydrophobicContact CB-CE2 4.31Å; V68-F320 HydrophobicContact CG2-CE2 3.9Å; V68-F320 HydrophobicContact CG2-CZ 3.84Å
69	C	93.5	Very high	86.2	Confident	27 Å²	27	62.5 Å²	62.5	18%	0.182	30%	0.296	C	S	.	.	H	α-helix	trans	-59.8	-49	176.3	-69	0	0	0	0	111.8	N65 A66 L67 I72 H73	N65-C69 PolarHBondContact O-N 3Å; N65-C69 VanDerWaalsContact O-N 3.08Å; N65-C69 PolarHBondContact O-SG 3.22Å; A66-C69 PolarHBondContact O-N 3.49Å; L67-C69 PolarHBondContact O-N 2.84Å; C69-I72 PolarHBondContact O-N 3.2Å; C69-H73 VanDerWaalsContact O-CB 3.26Å; C69-H73 WeakPolarHBondContact O-CB 3.39Å; C69-H73 PolarHBondContact O-N 3.37Å
70	L	91.4	Very high	85.5	Confident	88 Å²	88	59.7 Å²	59.7	46%	0.461	28%	0.283	S	S	.	.	H	α-helix	trans	-61.6	-48.2	-177.5	-178	143.2	0	0	0	112.4	A66 L67 I72 H73 R74 T327	A66-L70 WeakPolarHBondContact O-CB 3.33Å; A66-L70 PolarHBondContact O-N 2.88Å; L67-L70 PolarHBondContact O-N 3.36Å; L70-I72 PolarHBondContact O-N 3.19Å; L70-H73 PolarHBondContact O-N 3.45Å; L70-R74 VanDerWaalsContact O-CB 3.31Å; L70-R74 WeakPolarHBondContact O-CB 3.37Å; L70-R74 PolarHBondContact O-N 3.37Å; L70-T327 HydrophobicContact CD2-CG2 3.53Å
71	V	89.9	Confident	84.9	Confident	0 Å²	0	58.5 Å²	58.5	0%	0	28%	0.276	C	S	.	.	H	α-helix	trans	-62.1	-44.5	-178.4	164.8	0	0	0	0	111.4	L67 S75 F320 G323 M324	L67-V71 HydrophobicContact CD1-CG2 3.73Å; L67-V71 HydrophobicContact CG-CG2 4.08Å; L67-V71 WeakPolarHBondContact O-CB 3.3Å; L67-V71 VanDerWaalsContact O-CG2 3.23Å; L67-V71 WeakPolarHBondContact O-CG2 3.38Å; L67-V71 PolarHBondContact O-N 2.98Å; V71-S75 WeakPolarHBondContact O-CB 3.45Å; V71-S75 PolarHBondContact O-N 3.01Å; V71-S75 VanDerWaalsContact O-N 3.1Å; V71-F320 HydrophobicContact CB-CD2 4.12Å; V71-F320 HydrophobicContact CB-CE2 3.74Å; V71-F320 HydrophobicContact CG1-CD2 3.63Å; V71-F320 HydrophobicContact CG1-CE2 3.73Å; V71-F320 HydrophobicContact CG2-CE2 4.02Å; V71-G323 VanDerWaalsContact CG1-C 3.41Å; V71-M324 HydrophobicContact CG1-CG 4.29Å; V71-M324 HydrophobicContact CG2-CG 3.85Å
72	I	88.5	Confident	84.3	Confident	10 Å²	10	59 Å²	59	5%	0.051	28%	0.279	C	S	.	.	H	α-helix	trans	-71	-36.9	-179	-66.7	173.2	0	0	0	110.8	V68 C69 L70 N83 V86 V87	V68-I72 HydrophobicContact CG1-CD1 3.92Å; V68-I72 WeakPolarHBondContact O-CG1 3.07Å; V68-I72 PolarHBondContact O-N 2.67Å; C69-I72 PolarHBondContact O-N 3.2Å; L70-I72 PolarHBondContact O-N 3.19Å; I72-N83 HydrophobicContact CD1-CB 4.33Å; I72-N83 HydrophobicContact CG2-CB 3.81Å; I72-V86 HydrophobicContact CD1-CB 4.06Å; I72-V86 HydrophobicContact CD1-CG1 3.62Å; I72-V87 HydrophobicContact CB-CG2 3.7Å; I72-V87 HydrophobicContact CD1-CG2 3.66Å; I72-V87 HydrophobicContact CG1-CG2 4.26Å; I72-V87 HydrophobicContact CG2-CG2 3.48Å; I72-V87 VanDerWaalsContact CG2-CG2 3.48Å
73	H	85.3	Confident	83.9	Confident	165 Å²	165	57.5 Å²	57.5	76%	0.764	27%	0.272	S	S	*	.	H	α-helix	trans	-68.2	-44.7	177.7	-169.5	78.9	0	0	0	112	C69 L70	C69-H73 VanDerWaalsContact O-CB 3.26Å; C69-H73 WeakPolarHBondContact O-CB 3.39Å; C69-H73 PolarHBondContact O-N 3.37Å; L70-H73 PolarHBondContact O-N 3.45Å
74	R	83.9	Confident	83.7	Confident	142 Å²	142	54.5 Å²	54.5	54%	0.536	25%	0.252	S	S	.	.	H	α-helix	trans	-71.6	-37	-177.3	-168.4	177.7	179.7	122.6	-4.5	112.9	L70 R76	L70-R74 VanDerWaalsContact O-CB 3.31Å; L70-R74 WeakPolarHBondContact O-CB 3.37Å; L70-R74 PolarHBondContact O-N 3.37Å; R74-R76 PolarHBondContact O-N 2.85Å
75	S	78.9	Confident	83.6	Confident	3 Å²	3	53.9 Å²	53.9	2%	0.021	25%	0.246	C	C	.	.			trans	-87.9	96.8	-174.8	-176.5	0	0	0	0	112.9	V71 R77 T78 E326	V71-S75 WeakPolarHBondContact O-CB 3.45Å; V71-S75 PolarHBondContact O-N 3.01Å; V71-S75 VanDerWaalsContact O-N 3.1Å; S75-R77 PolarHBondContact O-N 3.44Å; S75-R77 VanDerWaalsContact O-N 3.13Å; S75-T78 PolarHBondContact O-N 3.25Å; S75-T78 PolarHBondContact O-OG1 3.02Å; S75-T78 VanDerWaalsContact OG-CG2 3.24Å; S75-T78 WeakPolarHBondContact OG-CG2 3.44Å; S75-E326 WeakPolarHBondContact CB-OE2 3.28Å; S75-E326 PolarHBondContact OG-OE2 2.93Å
76	R	64.5	Low	83.4	Confident	230 Å²	230	53.9 Å²	53.9	87%	0.868	25%	0.246	S	C	*	.	G	3₁₀ helix	trans	-54.5	-29.2	171	-79	-169.1	175.8	-139.9	0.9	113.2	R74 T78 Q79	R74-R76 PolarHBondContact O-N 2.85Å; R76-T78 VanDerWaalsContact C-N 3.3Å; R76-T78 PolarHBondContact O-N 2.99Å; R76-Q79 VanDerWaalsContact O-CG 3.3Å; R76-Q79 WeakPolarHBondContact O-CG 3.45Å
77	R	62.7	Low	83.3	Confident	180 Å²	180	53.7 Å²	53.7	68%	0.679	24%	0.24	S	C	*	.	G	3₁₀ helix	trans	-77.8	-11.3	-178.9	-70.2	-177.8	171.5	169.8	-5.8	113.8	S75	S75-R77 PolarHBondContact O-N 3.44Å; S75-R77 VanDerWaalsContact O-N 3.13Å
78	T	62.8	Low	83.5	Confident	2 Å²	2	51.8 Å²	51.8	1%	0.012	23%	0.231	C	C	.	.	G	3₁₀ helix	trans	-96.3	0.4	-179.8	65.5	0	0	0	0	114.2	S75 R76 S80 N83 N319	S75-T78 PolarHBondContact O-N 3.25Å; S75-T78 PolarHBondContact O-OG1 3.02Å; S75-T78 VanDerWaalsContact OG-CG2 3.24Å; S75-T78 WeakPolarHBondContact OG-CG2 3.44Å; R76-T78 VanDerWaalsContact C-N 3.3Å; R76-T78 PolarHBondContact O-N 2.99Å; T78-S80 VanDerWaalsContact C-N 3.34Å; T78-S80 PolarHBondContact O-N 3.38Å; T78-N83 WeakPolarHBondContact CB-ND2 3.38Å; T78-N83 VanDerWaalsContact O-CG 3.31Å; T78-N83 PolarHBondContact O-ND2 3.34Å; T78-N83 PolarHBondContact OG1-ND2 3.47Å; T78-N319 HydrophobicContact CG2-CB 4.07Å; T78-N319 WeakPolarHBondContact CG2-O 3.39Å
79	Q	65.4	Low	83.5	Confident	69 Å²	69	51.9 Å²	51.9	32%	0.322	23%	0.232	S	C	.	.			trans	-64.3	79.2	-173	-68.8	-100.7	-33.2	0	0	114.5	R76 Y84 R159	R76-Q79 VanDerWaalsContact O-CG 3.3Å; R76-Q79 WeakPolarHBondContact O-CG 3.45Å; Q79-Y84 PolarHBondContact OE1-OH 2.98Å; Q79-Y84 VanDerWaalsContact OE1-OH 3.08Å; Q79-R159 PolarHBondContact O-NH2 3.04Å
80	S	77.9	Confident	83.6	Confident	30 Å²	30	50.6 Å²	50.6	21%	0.21	22%	0.223	C	C	.	.			trans	-107.4	157.8	171.5	72.6	0	0	0	0	111.3	T78 T82 N83 Y84	T78-S80 VanDerWaalsContact C-N 3.34Å; T78-S80 PolarHBondContact O-N 3.38Å; S80-T82 PolarHBondContact O-N 2.95Å; S80-N83 WeakPolarHBondContact O-CB 3.21Å; S80-N83 PolarHBondContact O-N 3.36Å; S80-N83 PolarHBondContact OG-N 2.87Å; S80-N83 PolarHBondContact OG-OD1 3.4Å; S80-N83 VanDerWaalsContact OG-OD1 3.12Å; S80-Y84 WeakPolarHBondContact O-CD2 3.49Å
81	T	80.1	Confident	83.9	Confident	24 Å²	24	49 Å²	49	15%	0.147	22%	0.218	C	C	.	.	H	α-helix	trans	-57.3	-40.6	176.2	49.6	0	0	0	0	111.7	N83 Y84 F85 D144 V157 R159 A162	T81-N83 VanDerWaalsContact C-N 3.27Å; T81-N83 PolarHBondContact O-N 2.78Å; T81-Y84 PolarHBondContact O-N 3.31Å; T81-F85 WeakPolarHBondContact O-CD2 3.49Å; T81-D144 PolarHBondContact OG1-OD1 3.49Å; T81-V157 WeakPolarHBondContact CG2-O 3.48Å; T81-R159 HydrophobicContact CG2-CG 4.38Å; T81-A162 HydrophobicContact CG2-CB 4.29Å
82	T	81.9	Confident	84.2	Confident	10 Å²	10	49 Å²	49	6%	0.061	22%	0.218	C	C	.	.	H	α-helix	trans	-52.6	-40.6	172.5	-65.5	0	0	0	0	113.4	S80 Y84 F85 V86 R145 F259	S80-T82 PolarHBondContact O-N 2.95Å; T82-Y84 VanDerWaalsContact C-N 3.28Å; T82-Y84 PolarHBondContact O-N 3.02Å; T82-F85 PolarHBondContact O-N 3.35Å; T82-V86 HydrophobicContact CG2-CG2 4.21Å; T82-V86 WeakPolarHBondContact O-CG2 3.47Å; T82-V86 PolarHBondContact O-N 3.2Å; T82-R145 PolarHBondContact OG1-NH2 3.18Å; T82-F259 HydrophobicContact CG2-CE1 4.41Å; T82-F259 HydrophobicContact CG2-CE2 4.27Å; T82-F259 HydrophobicContact CG2-CZ 3.51Å
83	N	87.7	Confident	84.6	Confident	2 Å²	2	48.5 Å²	48.5	1%	0.011	22%	0.216	C	C	.	.	H	α-helix	trans	-66.6	-30.1	-176.7	-81.8	26.8	0	0	0	112.6	I72 T78 S80 T81 V86 V87	I72-N83 HydrophobicContact CD1-CB 4.33Å; I72-N83 HydrophobicContact CG2-CB 3.81Å; T78-N83 WeakPolarHBondContact CB-ND2 3.38Å; T78-N83 VanDerWaalsContact O-CG 3.31Å; T78-N83 PolarHBondContact O-ND2 3.34Å; T78-N83 PolarHBondContact OG1-ND2 3.47Å; S80-N83 WeakPolarHBondContact O-CB 3.21Å; S80-N83 PolarHBondContact O-N 3.36Å; S80-N83 PolarHBondContact OG-N 2.87Å; S80-N83 PolarHBondContact OG-OD1 3.4Å; S80-N83 VanDerWaalsContact OG-OD1 3.12Å; T81-N83 VanDerWaalsContact C-N 3.27Å; T81-N83 PolarHBondContact O-N 2.78Å; N83-V86 PolarHBondContact O-N 2.99Å; N83-V87 WeakPolarHBondContact O-CG2 3.46Å; N83-V87 PolarHBondContact O-N 3.24Å
84	Y	91.3	Very high	85.1	Confident	57 Å²	57	42.1 Å²	42.1	22%	0.224	19%	0.187	C	C	.	.	H	α-helix	trans	-65.7	-42.1	173.1	-68.8	-79.7	0	0	0	111.8	Q79 S80 T81 T82 V86 V87 S88 R159 K163 I166	Q79-Y84 PolarHBondContact OE1-OH 2.98Å; Q79-Y84 VanDerWaalsContact OE1-OH 3.08Å; S80-Y84 WeakPolarHBondContact O-CD2 3.49Å; T81-Y84 PolarHBondContact O-N 3.31Å; T82-Y84 VanDerWaalsContact C-N 3.28Å; T82-Y84 PolarHBondContact O-N 3.02Å; Y84-V86 VanDerWaalsContact C-N 3.33Å; Y84-V86 PolarHBondContact O-N 3.3Å; Y84-V87 PolarHBondContact O-N 2.87Å; Y84-S88 PolarHBondContact O-N 3.43Å; Y84-R159 HydrophobicContact CE2-CB 4.16Å; Y84-R159 HydrophobicContact CE2-CG 4.08Å; Y84-K163 HydrophobicContact CD1-CG 4.36Å; Y84-I166 WeakPolarHBondContact O-CD1 3.39Å
85	F	92.2	Very high	85.7	Confident	0 Å²	0	38.1 Å²	38.1	0%	0	18%	0.176	C	C	.	.	H	α-helix	trans	-65	-39	175.5	-61.2	-65.6	0	0	0	111.7	T81 T82 S88 M89 V137 I141 D144 A162 M165 I166	T81-F85 WeakPolarHBondContact O-CD2 3.49Å; T82-F85 PolarHBondContact O-N 3.35Å; F85-S88 PolarHBondContact O-N 2.86Å; F85-M89 WeakPolarHBondContact O-CG 3.29Å; F85-M89 PolarHBondContact O-N 3.13Å; F85-V137 HydrophobicContact CB-CG1 4.14Å; F85-V137 HydrophobicContact CD1-CG1 4.18Å; F85-I141 HydrophobicContact CB-CD1 3.73Å; F85-I141 HydrophobicContact CB-CG1 3.5Å; F85-I141 VanDerWaalsContact CB-CG1 3.5Å; F85-I141 HydrophobicContact CD1-CG1 4.2Å; F85-I141 HydrophobicContact CD2-CG1 3.89Å; F85-I141 HydrophobicContact CG-CD1 4.39Å; F85-I141 HydrophobicContact CG-CG1 3.63Å; F85-D144 HydrophobicContact CE2-CB 3.97Å; F85-D144 HydrophobicContact CZ-CB 4.37Å; F85-A162 HydrophobicContact CE2-CB 3.98Å; F85-A162 HydrophobicContact CZ-CB 3.81Å; F85-M165 HydrophobicContact CE1-CB 4.2Å; F85-M165 HydrophobicContact CZ-CB 4.43Å; F85-M165 HydrophobicContact CZ-CE 4.24Å; F85-M165 HydrophobicContact CZ-SD 4.33Å; F85-I166 HydrophobicContact CD1-CD1 3.78Å; F85-I166 HydrophobicContact CD1-CG1 3.46Å; F85-I166 VanDerWaalsContact CD1-CG1 3.46Å; F85-I166 HydrophobicContact CE1-CD1 4.17Å; F85-I166 HydrophobicContact CE1-CG1 3.67Å; F85-I166 HydrophobicContact CG-CD1 4.39Å; F85-I166 HydrophobicContact CG-CG1 4.49Å
86	V	91.9	Very high	86.4	Confident	0 Å²	0	38 Å²	38	0%	0	18%	0.175	C	C	.	.	H	α-helix	trans	-61.8	-44.7	175.3	172	0	0	0	0	111.6	V68 I72 T82 N83 Y84 M89 A90 Y313	V68-V86 HydrophobicContact CG1-CG1 3.6Å; I72-V86 HydrophobicContact CD1-CB 4.06Å; I72-V86 HydrophobicContact CD1-CG1 3.62Å; T82-V86 HydrophobicContact CG2-CG2 4.21Å; T82-V86 WeakPolarHBondContact O-CG2 3.47Å; T82-V86 PolarHBondContact O-N 3.2Å; N83-V86 PolarHBondContact O-N 2.99Å; Y84-V86 VanDerWaalsContact C-N 3.33Å; Y84-V86 PolarHBondContact O-N 3.3Å; V86-M89 HydrophobicContact CG2-CE 4.23Å; V86-M89 PolarHBondContact O-N 3.17Å; V86-A90 PolarHBondContact O-N 3.27Å; V86-Y313 HydrophobicContact CG1-CD1 4.28Å; V86-Y313 HydrophobicContact CG1-CD2 3.98Å; V86-Y313 HydrophobicContact CG1-CE1 4.02Å; V86-Y313 HydrophobicContact CG1-CE2 3.73Å; V86-Y313 HydrophobicContact CG1-CG 4.28Å; V86-Y313 HydrophobicContact CG2-CD1 4.4Å; V86-Y313 HydrophobicContact CG2-CE1 3.91Å
87	V	93.7	Very high	87.8	Confident	39 Å²	39	27.1 Å²	27.1	24%	0.236	13%	0.134	C	C	.	.	H	α-helix	trans	-63.2	-43.4	174.2	171.7	0	0	0	0	111	I72 N83 Y84 M89 A90 C91	I72-V87 HydrophobicContact CB-CG2 3.7Å; I72-V87 HydrophobicContact CD1-CG2 3.66Å; I72-V87 HydrophobicContact CG1-CG2 4.26Å; I72-V87 HydrophobicContact CG2-CG2 3.48Å; I72-V87 VanDerWaalsContact CG2-CG2 3.48Å; N83-V87 WeakPolarHBondContact O-CG2 3.46Å; N83-V87 PolarHBondContact O-N 3.24Å; Y84-V87 PolarHBondContact O-N 2.87Å; V87-M89 VanDerWaalsContact C-N 3.31Å; V87-M89 PolarHBondContact O-N 3.02Å; V87-A90 CarbonylContact O-C 3.45Å; V87-A90 PolarHBondContact O-N 3.47Å; V87-A90 VanDerWaalsContact O-N 3.15Å; V87-C91 PolarHBondContact O-N 3.41Å; V87-C91 PolarHBondContact O-SG 2.8Å
88	S	95.9	Very high	89.3	Confident	9 Å²	9	23.4 Å²	23.4	6%	0.063	13%	0.127	C	C	.	.	H	α-helix	trans	-59.3	-41.4	177	-176	0	0	0	0	112.4	Y84 F85 C91 A92 I166 W170	Y84-S88 PolarHBondContact O-N 3.43Å; F85-S88 PolarHBondContact O-N 2.86Å; S88-C91 PolarHBondContact O-N 3.13Å; S88-A92 PolarHBondContact O-N 3.25Å; S88-I166 WeakPolarHBondContact OG-CG2 3.5Å; S88-W170 PolarHBondContact OG-NE1 3.04Å
89	M	94.4	Very high	90.7	Very high	3 Å²	3	23.9 Å²	23.9	2%	0.015	13%	0.133	C	C	.	.	H	α-helix	trans	-63.6	-46.2	174.3	-73.7	-176.5	-71.5	0	0	111	F85 V86 V87 C91 A92 D93 V137 L138 I141 Y313	F85-M89 WeakPolarHBondContact O-CG 3.29Å; F85-M89 PolarHBondContact O-N 3.13Å; V86-M89 HydrophobicContact CG2-CE 4.23Å; V86-M89 PolarHBondContact O-N 3.17Å; V87-M89 VanDerWaalsContact C-N 3.31Å; V87-M89 PolarHBondContact O-N 3.02Å; M89-C91 VanDerWaalsContact C-N 3.29Å; M89-C91 PolarHBondContact O-N 2.88Å; M89-A92 PolarHBondContact O-N 3.49Å; M89-A92 VanDerWaalsContact O-N 3.15Å; M89-D93 WeakPolarHBondContact O-CB 3.47Å; M89-D93 PolarHBondContact O-N 3.16Å; M89-V137 HydrophobicContact CG-CB 4.41Å; M89-V137 HydrophobicContact CG-CG1 3.69Å; M89-V137 HydrophobicContact SD-CG1 4.42Å; M89-L138 HydrophobicContact SD-CD2 3.84Å; M89-L138 HydrophobicContact SD-CG 4.29Å; M89-I141 HydrophobicContact CE-CD1 3.45Å; M89-I141 VanDerWaalsContact CE-CD1 3.45Å; M89-I141 HydrophobicContact SD-CD1 4Å; M89-Y313 WeakPolarHBondContact CE-OH 3.44Å
90	A	95.9	Very high	92	Very high	0 Å²	0	21 Å²	21	0%	0	12%	0.119	C	C	.	.	H	α-helix	trans	-61	-36.4	177	0	0	0	0	0	112.5	N65 V68 V86 V87 D93 L94	N65-A90 HydrophobicContact CB-CB 4.13Å; V68-A90 HydrophobicContact CB-CB 4.13Å; V68-A90 HydrophobicContact CG1-CB 3.84Å; V86-A90 PolarHBondContact O-N 3.27Å; V87-A90 CarbonylContact O-C 3.45Å; V87-A90 PolarHBondContact O-N 3.47Å; V87-A90 VanDerWaalsContact O-N 3.15Å; A90-D93 PolarHBondContact O-N 3.17Å; A90-L94 WeakPolarHBondContact O-CB 3.29Å; A90-L94 VanDerWaalsContact O-CG 3.25Å; A90-L94 WeakPolarHBondContact O-CG 3.34Å; A90-L94 PolarHBondContact O-N 3.34Å
91	C	96.6	Very high	92.5	Very high	53 Å²	53	19.5 Å²	19.5	36%	0.358	11%	0.109	S	C	.	.	H	α-helix	trans	-65.7	-43	173.3	-69.9	0	0	0	0	112.2	V87 S88 M89 D93 L94 L95	V87-C91 PolarHBondContact O-N 3.41Å; V87-C91 PolarHBondContact O-SG 2.8Å; S88-C91 PolarHBondContact O-N 3.13Å; M89-C91 VanDerWaalsContact C-N 3.29Å; M89-C91 PolarHBondContact O-N 2.88Å; C91-D93 VanDerWaalsContact C-N 3.31Å; C91-D93 PolarHBondContact O-N 3.4Å; C91-L94 PolarHBondContact O-N 2.85Å; C91-L95 WeakPolarHBondContact O-CB 3.05Å; C91-L95 PolarHBondContact O-N 3.35Å
92	A	96.8	Very high	93	Very high	0 Å²	0	20.3 Å²	20.3	0%	0	12%	0.115	C	C	.	.	H	α-helix	trans	-62.6	-40.4	173.8	0	0	0	0	0	111.2	S88 M89 L95 M96 V133 Q134 W170	S88-A92 PolarHBondContact O-N 3.25Å; M89-A92 PolarHBondContact O-N 3.49Å; M89-A92 VanDerWaalsContact O-N 3.15Å; A92-L95 PolarHBondContact O-N 3.41Å; A92-M96 WeakPolarHBondContact O-CG 3.25Å; A92-M96 PolarHBondContact O-N 2.77Å; A92-V133 HydrophobicContact CB-CG1 4.32Å; A92-Q134 HydrophobicContact CB-CG 3.91Å; A92-W170 HydrophobicContact CB-CH2 4.32Å; A92-W170 HydrophobicContact CB-CZ2 4.22Å
93	D	96.1	Very high	93.4	Very high	0 Å²	0	23.1 Å²	23.1	0%	0	13%	0.126	C	C	.	.	H	α-helix	trans	-63.9	-41.9	176.5	-68.8	-33.4	0	0	0	113	N65 M89 A90 C91 M96 S97 Q134 T306 K309	N65-D93 HydrophobicContact CB-CB 4.3Å; N65-D93 PolarHBondContact OD1-OD2 3.42Å; M89-D93 WeakPolarHBondContact O-CB 3.47Å; M89-D93 PolarHBondContact O-N 3.16Å; A90-D93 PolarHBondContact O-N 3.17Å; C91-D93 VanDerWaalsContact C-N 3.31Å; C91-D93 PolarHBondContact O-N 3.4Å; D93-M96 HydrophobicContact CB-CE 4.34Å; D93-M96 PolarHBondContact O-N 3.17Å; D93-M96 WeakPolarHBondContact OD1-CE 3.26Å; D93-S97 WeakPolarHBondContact O-CB 3.4Å; D93-S97 PolarHBondContact O-N 3.2Å; D93-S97 PolarHBondContact O-OG 3Å; D93-Q134 PolarHBondContact OD1-OE1 2.98Å; D93-T306 HydrophobicContact CB-CG2 3.45Å; D93-T306 VanDerWaalsContact CB-CG2 3.45Å; D93-T306 WeakPolarHBondContact OD1-CG2 3.18Å; D93-K309 IonicContact OD1-NZ 3.91Å; D93-K309 PolarHBondContact OD1-NZ 3.08Å; D93-K309 WeakPolarHBondContact OD2-CD 3.46Å; D93-K309 IonicContact OD2-NZ 2.74Å; D93-K309 PolarHBondContact OD2-NZ 3Å
94	L	96.6	Very high	93.3	Very high	32 Å²	32	23.4 Å²	23.4	17%	0.168	13%	0.128	C	C	.	.	H	α-helix	trans	-65.6	-40.4	172.8	-72.2	169.4	0	0	0	111.4	I62 N65 A66 A90 C91 M96 S97 L98	I62-L94 HydrophobicContact CG2-CD2 4.48Å; N65-L94 HydrophobicContact CB-CD2 4.03Å; N65-L94 HydrophobicContact CB-CG 3.9Å; A66-L94 HydrophobicContact CB-CD2 4.38Å; A90-L94 WeakPolarHBondContact O-CB 3.29Å; A90-L94 VanDerWaalsContact O-CG 3.25Å; A90-L94 WeakPolarHBondContact O-CG 3.34Å; A90-L94 PolarHBondContact O-N 3.34Å; C91-L94 PolarHBondContact O-N 2.85Å; L94-M96 VanDerWaalsContact C-N 3.33Å; L94-M96 PolarHBondContact O-N 3.07Å; L94-S97 PolarHBondContact O-N 2.72Å; L94-L98 WeakPolarHBondContact O-CB 3.22Å; L94-L98 WeakPolarHBondContact O-CG 3.39Å; L94-L98 PolarHBondContact O-N 2.88Å
95	L	96.1	Very high	92.9	Very high	58 Å²	58	23.9 Å²	23.9	30%	0.304	13%	0.134	S	C	.	.	H	α-helix	trans	-65.2	-35.5	175.7	-173.4	60.8	0	0	0	111.7	C91 A92 G99 L126 C130 W170	C91-L95 WeakPolarHBondContact O-CB 3.05Å; C91-L95 PolarHBondContact O-N 3.35Å; A92-L95 PolarHBondContact O-N 3.41Å; L95-G99 WeakPolarHBondContact O-CA 3.38Å; L95-G99 PolarHBondContact O-N 2.85Å; L95-L126 HydrophobicContact CD1-CD1 4.42Å; L95-L126 HydrophobicContact CD1-CD2 4.15Å; L95-L126 HydrophobicContact CD2-CD2 3.91Å; L95-L126 HydrophobicContact CG-CD2 4.03Å; L95-C130 VanDerWaalsContact CG-SG 3.58Å; L95-W170 HydrophobicContact CD2-CH2 4.19Å; L95-W170 HydrophobicContact CD2-CZ3 4.06Å
96	M	93.7	Very high	92.7	Very high	1 Å²	1	27.6 Å²	27.6	1%	0.005	15%	0.153	C	C	.	.	H	α-helix	trans	-63.6	-50.1	168.6	-67.1	-169.5	-66.9	0	0	112	A92 D93 L94 L98 W100 A101 C130 Q134 W270 T306	A92-M96 WeakPolarHBondContact O-CG 3.25Å; A92-M96 PolarHBondContact O-N 2.77Å; D93-M96 HydrophobicContact CB-CE 4.34Å; D93-M96 PolarHBondContact O-N 3.17Å; D93-M96 WeakPolarHBondContact OD1-CE 3.26Å; L94-M96 VanDerWaalsContact C-N 3.33Å; L94-M96 PolarHBondContact O-N 3.07Å; M96-L98 VanDerWaalsContact C-N 3.33Å; M96-L98 PolarHBondContact O-N 2.97Å; M96-W100 PolarHBondContact O-N 3.49Å; M96-A101 VanDerWaalsContact O-CB 3.31Å; M96-A101 WeakPolarHBondContact O-CB 3.17Å; M96-A101 PolarHBondContact O-N 2.84Å; M96-C130 HydrophobicContact CB-CB 4.4Å; M96-C130 HydrophobicContact CG-CB 3.07Å; M96-C130 HydrophobicContact SD-CB 3.77Å; M96-Q134 PolarHBondContact SD-NE2 3.46Å; M96-W270 HydrophobicContact CE-CZ2 4.41Å; M96-W270 HydrophobicContact SD-CH2 3.93Å; M96-W270 HydrophobicContact SD-CZ2 3.61Å; M96-T306 HydrophobicContact CE-CG2 3.87Å; M96-T306 WeakPolarHBondContact CE-OG1 3.27Å
97	S	94.5	Very high	92.4	Very high	0 Å²	0	28.1 Å²	28.1	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-65.3	-36.6	-172.8	-54.6	0	0	0	0	112.4	W58 S61 D93 L94 P102 F303	W58-S97 PolarHBondContact NE1-O 3.49Å; S61-S97 PolarHBondContact OG-OG 3.28Å; D93-S97 WeakPolarHBondContact O-CB 3.4Å; D93-S97 PolarHBondContact O-N 3.2Å; D93-S97 PolarHBondContact O-OG 3Å; L94-S97 PolarHBondContact O-N 2.72Å; S97-P102 VanDerWaalsContact O-CD 3.27Å; S97-P102 WeakPolarHBondContact O-CD 3.47Å; S97-F303 WeakPolarHBondContact OG-CZ 3.33Å
98	L	94.3	Very high	91.8	Very high	102 Å²	102	27.7 Å²	27.7	53%	0.534	15%	0.153	S	C	.	.	H	α-helix	trans	-96.4	-25.8	-179.9	-62	174.2	0	0	0	112.7	I62 L94 M96	I62-L98 HydrophobicContact CD1-CD2 3.61Å; I62-L98 HydrophobicContact CD1-CG 4.43Å; I62-L98 HydrophobicContact CG1-CD2 4.31Å; L94-L98 WeakPolarHBondContact O-CB 3.22Å; L94-L98 WeakPolarHBondContact O-CG 3.39Å; L94-L98 PolarHBondContact O-N 2.88Å; M96-L98 VanDerWaalsContact C-N 3.33Å; M96-L98 PolarHBondContact O-N 2.97Å
99	G	92.7	Very high	91.1	Very high	13 Å²	13	31 Å²	31	13%	0.134	18%	0.181	C	C	.	.	H	α-helix	trans	-92.6	-50.9	-165.9	0	0	0	0	0	115.1	L95 F103	L95-G99 WeakPolarHBondContact O-CA 3.38Å; L95-G99 PolarHBondContact O-N 2.85Å; G99-F103 WeakPolarHBondContact O-CD2 3.39Å; G99-F103 WeakPolarHBondContact O-CE2 3.29Å
100	W	91.3	Very high	90.5	Very high	7 Å²	7	33.1 Å²	33.1	3%	0.027	20%	0.199	C	C	.	.	T	Hydrogen-bonded Turn	trans	-117	-34.4	-176.7	72	-102.1	0	0	0	113.2	M96 F103 V104 V123 L126 Q127 W270	M96-W100 PolarHBondContact O-N 3.49Å; W100-F103 PolarHBondContact O-N 3.38Å; W100-V104 HydrophobicContact CE3-CB 4.11Å; W100-V104 HydrophobicContact CE3-CG2 3.64Å; W100-V104 HydrophobicContact CZ3-CB 4.23Å; W100-V104 HydrophobicContact CZ3-CG1 4.38Å; W100-V104 HydrophobicContact CZ3-CG2 4.01Å; W100-V104 PolarHBondContact O-N 2.92Å; W100-V123 HydrophobicContact CB-CG1 3.92Å; W100-V123 WeakPolarHBondContact CB-O 3.41Å; W100-L126 HydrophobicContact CB-CB 4.22Å; W100-Q127 HydrophobicContact CB-CB 4.32Å; W100-Q127 HydrophobicContact CD2-CB 4.17Å; W100-Q127 HydrophobicContact CD2-CG 4.15Å; W100-Q127 HydrophobicContact CE3-CG 4.2Å; W100-Q127 HydrophobicContact CG-CB 4.06Å; W100-W270 HydrophobicContact CZ2-CH2 4.22Å
101	A	89.6	Confident	89.7	Confident	0 Å²	0	35.5 Å²	35.5	0%	0	22%	0.223	C	C	.	.	H	α-helix	trans	-54.5	-49	-177.1	0	0	0	0	0	114.7	F54 M96 F103 V104 L105 F303	F54-A101 HydrophobicContact CZ-CB 4.15Å; M96-A101 VanDerWaalsContact O-CB 3.31Å; M96-A101 WeakPolarHBondContact O-CB 3.17Å; M96-A101 PolarHBondContact O-N 2.84Å; A101-F103 VanDerWaalsContact C-N 3.3Å; A101-F103 PolarHBondContact O-N 3.46Å; A101-V104 PolarHBondContact O-N 3.37Å; A101-L105 PolarHBondContact O-N 2.86Å; A101-L105 VanDerWaalsContact O-N 3.09Å; A101-F303 HydrophobicContact CB-CD2 4.09Å; A101-F303 HydrophobicContact CB-CE2 3.55Å
102	P	89.6	Confident	89.1	Confident	41 Å²	41	39.6 Å²	39.6	27%	0.266	24%	0.237	S	C	.	.	H	α-helix	trans	-68.2	-31.3	-179.5	25.1	-33.9	0	0	0	112.5	S97 L105 L106	S97-P102 VanDerWaalsContact O-CD 3.27Å; S97-P102 WeakPolarHBondContact O-CD 3.47Å; P102-L105 PolarHBondContact O-N 3.37Å; P102-L106 WeakPolarHBondContact O-CB 3.23Å; P102-L106 PolarHBondContact O-N 2.92Å
103	F	90.1	Very high	88.6	Confident	69 Å²	69	40.8 Å²	40.8	30%	0.303	24%	0.242	S	C	.	.	H	α-helix	trans	-74.9	-35.5	179.8	-61.7	-82.5	0	0	0	112.4	G99 W100 A101 L106 Q107 W113 L115 V123	G99-F103 WeakPolarHBondContact O-CD2 3.39Å; G99-F103 WeakPolarHBondContact O-CE2 3.29Å; W100-F103 PolarHBondContact O-N 3.38Å; A101-F103 VanDerWaalsContact C-N 3.3Å; A101-F103 PolarHBondContact O-N 3.46Å; F103-L106 WeakPolarHBondContact O-CB 3.35Å; F103-L106 PolarHBondContact O-N 3.21Å; F103-Q107 PolarHBondContact O-N 2.89Å; F103-W113 HydrophobicContact CB-CH2 4.04Å; F103-W113 HydrophobicContact CB-CZ3 4.27Å; F103-L115 HydrophobicContact CD1-CD1 3.4Å; F103-L115 VanDerWaalsContact CD1-CD1 3.4Å; F103-L115 HydrophobicContact CE1-CD1 3.69Å; F103-V123 HydrophobicContact CB-CG1 3.97Å; F103-V123 HydrophobicContact CB-CG2 3.8Å; F103-V123 HydrophobicContact CD1-CG2 4.39Å; F103-V123 HydrophobicContact CD2-CG2 3.87Å; F103-V123 HydrophobicContact CG-CG2 3.75Å
104	V	85.7	Confident	88.2	Confident	8 Å²	8	43.9 Å²	43.9	5%	0.048	26%	0.262	C	S	.	.	H	α-helix	trans	-63.5	-44.1	169.8	160.4	0	0	0	0	110.7	W100 A101 L106 Q107 V108 F193 F295	W100-V104 HydrophobicContact CE3-CB 4.11Å; W100-V104 HydrophobicContact CE3-CG2 3.64Å; W100-V104 HydrophobicContact CZ3-CB 4.23Å; W100-V104 HydrophobicContact CZ3-CG1 4.38Å; W100-V104 HydrophobicContact CZ3-CG2 4.01Å; W100-V104 PolarHBondContact O-N 2.92Å; A101-V104 PolarHBondContact O-N 3.37Å; V104-L106 VanDerWaalsContact C-N 3.3Å; V104-L106 PolarHBondContact O-N 2.91Å; V104-Q107 WeakPolarHBondContact O-CB 3.09Å; V104-Q107 PolarHBondContact O-N 3.25Å; V104-V108 VanDerWaalsContact O-CG2 3.31Å; V104-V108 WeakPolarHBondContact O-CG2 3.41Å; V104-V108 PolarHBondContact O-N 3.41Å; V104-F193 HydrophobicContact CG1-CE1 4.21Å; V104-F295 HydrophobicContact CG1-CE1 3.65Å; V104-F295 HydrophobicContact CG1-CZ 4.44Å
105	L	83.9	Confident	87.9	Confident	67 Å²	67	45.7 Å²	45.7	35%	0.351	27%	0.271	S	S	.	.	H	α-helix	trans	-61.8	-41.5	175.4	-177.9	66.2	0	0	0	111.6	F54 A101 P102 Q107 V108 A109	F54-L105 HydrophobicContact CD1-CD1 4.31Å; F54-L105 HydrophobicContact CD1-CD2 3.81Å; F54-L105 HydrophobicContact CD1-CG 4.48Å; F54-L105 HydrophobicContact CE1-CB 4.15Å; F54-L105 HydrophobicContact CE1-CD2 3.94Å; F54-L105 HydrophobicContact CE1-CG 4.47Å; A101-L105 PolarHBondContact O-N 2.86Å; A101-L105 VanDerWaalsContact O-N 3.09Å; P102-L105 PolarHBondContact O-N 3.37Å; L105-Q107 VanDerWaalsContact C-N 3.33Å; L105-Q107 PolarHBondContact O-N 2.85Å; L105-V108 PolarHBondContact O-N 3.36Å; L105-A109 WeakPolarHBondContact O-CB 3.42Å; L105-A109 PolarHBondContact O-N 3.08Å
106	L	86.6	Confident	87.7	Confident	78 Å²	78	46.4 Å²	46.4	41%	0.408	28%	0.281	S	S	.	.	H	α-helix	trans	-60.1	-43.4	175.2	177.9	62.9	0	0	0	111.5	P102 F103 V104 A109 A110 P114 L115	P102-L106 WeakPolarHBondContact O-CB 3.23Å; P102-L106 PolarHBondContact O-N 2.92Å; F103-L106 WeakPolarHBondContact O-CB 3.35Å; F103-L106 PolarHBondContact O-N 3.21Å; V104-L106 VanDerWaalsContact C-N 3.3Å; V104-L106 PolarHBondContact O-N 2.91Å; L106-A109 PolarHBondContact O-N 3.48Å; L106-A110 VanDerWaalsContact O-CB 3.24Å; L106-A110 WeakPolarHBondContact O-CB 3.33Å; L106-A110 PolarHBondContact O-N 3.44Å; L106-P114 HydrophobicContact CD1-CG 4.35Å; L106-P114 HydrophobicContact CD2-CG 3.76Å; L106-P114 HydrophobicContact CG-CG 3.7Å; L106-L115 HydrophobicContact CD2-CD1 4.48Å
107	Q	85.4	Confident	87.5	Confident	10 Å²	10	48.1 Å²	48.1	5%	0.047	30%	0.295	C	S	.	.	H	α-helix	trans	-62.1	-43.2	174.9	-176.6	-179.5	2	0	0	112	F103 V104 L105 A110 G111 W113 C191 F193	F103-Q107 PolarHBondContact O-N 2.89Å; V104-Q107 WeakPolarHBondContact O-CB 3.09Å; V104-Q107 PolarHBondContact O-N 3.25Å; L105-Q107 VanDerWaalsContact C-N 3.33Å; L105-Q107 PolarHBondContact O-N 2.85Å; Q107-A110 PolarHBondContact O-N 2.89Å; Q107-G111 PolarHBondContact O-N 3.28Å; Q107-W113 HydrophobicContact CB-CE3 4Å; Q107-W113 HydrophobicContact CB-CZ3 4.41Å; Q107-W113 HydrophobicContact CG-CE3 4.14Å; Q107-C191 PolarHBondContact NE2-O 2.88Å; Q107-F193 HydrophobicContact CB-CE1 4.42Å; Q107-F193 HydrophobicContact CB-CZ 4.15Å; Q107-F193 HydrophobicContact CG-CE1 4.12Å; Q107-F193 HydrophobicContact CG-CE2 4.29Å; Q107-F193 HydrophobicContact CG-CZ 3.6Å; Q107-F193 VanDerWaalsContact OE1-CE1 3.25Å
108	V	81.4	Confident	87.3	Confident	31 Å²	31	51.1 Å²	51.1	19%	0.188	32%	0.32	C	S	.	.	H	α-helix	trans	-62.1	-44.8	176.6	171.3	0	0	0	0	110.9	V104 L105 G111 F193 L292	V104-V108 VanDerWaalsContact O-CG2 3.31Å; V104-V108 WeakPolarHBondContact O-CG2 3.41Å; V104-V108 PolarHBondContact O-N 3.41Å; L105-V108 PolarHBondContact O-N 3.36Å; V108-G111 PolarHBondContact O-N 2.88Å; V108-F193 HydrophobicContact CG2-CE1 4.34Å; V108-F193 HydrophobicContact CG2-CZ 3.87Å; V108-L292 HydrophobicContact CB-CD1 4.23Å; V108-L292 HydrophobicContact CG1-CD1 4.02Å; V108-L292 HydrophobicContact CG1-CD2 4.39Å; V108-L292 HydrophobicContact CG1-CG 4.34Å; V108-L292 HydrophobicContact CG2-CD1 3.82Å
109	A	81.6	Confident	87.2	Confident	79 Å²	79	47.6 Å²	47.6	65%	0.653	31%	0.306	S	S	*	.	H	α-helix	trans	-69.8	-35.4	-179.4	0	0	0	0	0	112.9	L105 L106	L105-A109 WeakPolarHBondContact O-CB 3.42Å; L105-A109 PolarHBondContact O-N 3.08Å; L106-A109 PolarHBondContact O-N 3.48Å
110	A	83	Confident	87.2	Confident	46 Å²	46	47 Å²	47	38%	0.38	30%	0.3	S	S	.	.	H	α-helix	trans	-81.5	-15	178.3	0	0	0	0	0	113.3	L106 Q107 Q112 P114	L106-A110 VanDerWaalsContact O-CB 3.24Å; L106-A110 WeakPolarHBondContact O-CB 3.33Å; L106-A110 PolarHBondContact O-N 3.44Å; Q107-A110 PolarHBondContact O-N 2.89Å; A110-Q112 PolarHBondContact O-N 3.27Å; A110-Q112 VanDerWaalsContact O-N 3.1Å; A110-P114 HydrophobicContact CB-CG 4.35Å
111	G	78.2	Confident	87.3	Confident	50 Å²	50	50.2 Å²	50.2	52%	0.515	31%	0.314	S	S	.	.	S	Bend	trans	71.4	-8.2	-173.7	0	0	0	0	0	114.6	Q107 V108	Q107-G111 PolarHBondContact O-N 3.28Å; V108-G111 PolarHBondContact O-N 2.88Å
112	Q	83.1	Confident	87.5	Confident	139 Å²	139	53.8 Å²	53.8	65%	0.65	34%	0.335	S	S	*	.	S	Bend	trans	-148	168	179.8	60.7	180	-18.9	0	0	109.7	A110 P114	A110-Q112 PolarHBondContact O-N 3.27Å; A110-Q112 VanDerWaalsContact O-N 3.1Å; Q112-P114 VanDerWaalsContact O-CD 3.26Å; Q112-P114 WeakPolarHBondContact O-CD 3.5Å
113	W	87.9	Confident	87.7	Confident	26 Å²	26	52 Å²	52	10%	0.098	32%	0.324	C	S	.	.			trans	-79.5	114.1	175.8	-178.3	-102.4	0	0	0	111.1	F103 Q107 L115 S116 A119 C120 V123 C191	F103-W113 HydrophobicContact CB-CH2 4.04Å; F103-W113 HydrophobicContact CB-CZ3 4.27Å; Q107-W113 HydrophobicContact CB-CE3 4Å; Q107-W113 HydrophobicContact CB-CZ3 4.41Å; Q107-W113 HydrophobicContact CG-CE3 4.14Å; W113-L115 HydrophobicContact CH2-CD1 4.42Å; W113-L115 HydrophobicContact CZ2-CB 3.82Å; W113-L115 HydrophobicContact CZ2-CD1 4.14Å; W113-L115 HydrophobicContact CZ2-CG 4.45Å; W113-L115 VanDerWaalsContact NE1-C 3.35Å; W113-L115 PolarHBondContact NE1-O 3Å; W113-S116 PolarHBondContact NE1-O 3.33Å; W113-S116 VanDerWaalsContact NE1-O 3.08Å; W113-A119 HydrophobicContact CZ2-CB 3.98Å; W113-C120 HydrophobicContact CD2-CB 4.41Å; W113-C120 VanDerWaalsContact CZ2-CA 3.43Å; W113-C120 HydrophobicContact CZ2-CB 4.01Å; W113-C120 VanDerWaalsContact CZ2-N 3.31Å; W113-V123 HydrophobicContact CH2-CB 3.93Å; W113-V123 HydrophobicContact CH2-CG1 4Å; W113-V123 HydrophobicContact CH2-CG2 3.92Å; W113-V123 HydrophobicContact CZ3-CG1 4.31Å; W113-C191 HydrophobicContact CB-CB 3.51Å; W113-C191 HydrophobicContact CD2-CB 3.64Å; W113-C191 VanDerWaalsContact CD2-SG 3.58Å; W113-C191 HydrophobicContact CE3-CB 4.13Å; W113-C191 HydrophobicContact CG-CB 3.33Å
114	P	87.6	Confident	87.9	Confident	64 Å²	64	48.8 Å²	48.8	42%	0.416	31%	0.31	S	S	.	.			trans	-93.7	-0.4	-171.1	34.9	-30.4	0	0	0	113.8	L106 A110 Q112	L106-P114 HydrophobicContact CD1-CG 4.35Å; L106-P114 HydrophobicContact CD2-CG 3.76Å; L106-P114 HydrophobicContact CG-CG 3.7Å; A110-P114 HydrophobicContact CB-CG 4.35Å; Q112-P114 VanDerWaalsContact O-CD 3.26Å; Q112-P114 WeakPolarHBondContact O-CD 3.5Å
115	L	90.3	Very high	88.3	Confident	71 Å²	71	50.2 Å²	50.2	37%	0.372	31%	0.314	S	S	.	.	S	Bend	trans	-109	178.8	-175.7	-61.9	178.1	0	0	0	111.5	F103 L106 W113 A119	F103-L115 HydrophobicContact CD1-CD1 3.4Å; F103-L115 VanDerWaalsContact CD1-CD1 3.4Å; F103-L115 HydrophobicContact CE1-CD1 3.69Å; L106-L115 HydrophobicContact CD2-CD1 4.48Å; W113-L115 HydrophobicContact CH2-CD1 4.42Å; W113-L115 HydrophobicContact CZ2-CB 3.82Å; W113-L115 HydrophobicContact CZ2-CD1 4.14Å; W113-L115 HydrophobicContact CZ2-CG 4.45Å; W113-L115 VanDerWaalsContact NE1-C 3.35Å; W113-L115 PolarHBondContact NE1-O 3Å; L115-A119 HydrophobicContact CB-CB 3.84Å; L115-A119 HydrophobicContact CD1-CB 4.26Å
116	S	90.5	Very high	88.9	Confident	72 Å²	72	48.1 Å²	48.1	50%	0.503	30%	0.303	S	S	.	.			trans	-65.7	160	178.7	68.8	0	0	0	0	113.1	W113 A118 A119 C120	W113-S116 PolarHBondContact NE1-O 3.33Å; W113-S116 VanDerWaalsContact NE1-O 3.08Å; S116-A118 PolarHBondContact O-N 2.73Å; S116-A119 WeakPolarHBondContact O-CB 3.32Å; S116-A119 PolarHBondContact O-N 2.62Å; S116-A119 VanDerWaalsContact O-N 3.11Å; S116-A119 PolarHBondContact OG-N 2.98Å; S116-C120 PolarHBondContact O-N 3.43Å
117	A	89.4	Confident	89.2	Confident	37 Å²	37	44.4 Å²	44.4	31%	0.306	28%	0.284	S	S	.	.	H	α-helix	trans	-60.3	-33	172.4	0	0	0	0	0	112.5	C120 K121	A117-C120 WeakPolarHBondContact O-CB 3.34Å; A117-C120 PolarHBondContact O-N 3Å; A117-K121 PolarHBondContact O-N 3.4Å
118	A	91	Very high	89.6	Confident	64 Å²	64	44.3 Å²	44.3	53%	0.529	28%	0.283	S	S	.	.	H	α-helix	trans	-64.3	-42.2	173.3	0	0	0	0	0	111.8	S116 C120 K121 V122	S116-A118 PolarHBondContact O-N 2.73Å; A118-C120 VanDerWaalsContact C-N 3.32Å; A118-C120 PolarHBondContact O-N 3.49Å; A118-K121 WeakPolarHBondContact O-CB 3.08Å; A118-K121 PolarHBondContact O-N 3.32Å; A118-V122 WeakPolarHBondContact O-CG2 3.48Å; A118-V122 PolarHBondContact O-N 2.87Å; A118-V122 VanDerWaalsContact O-N 3.1Å
119	A	92.5	Very high	90.4	Very high	27 Å²	27	43.3 Å²	43.3	22%	0.223	28%	0.277	C	S	.	.	H	α-helix	trans	-63.2	-40.1	174.6	0	0	0	0	0	111.4	W113 L115 S116 K121 V122 V123	W113-A119 HydrophobicContact CZ2-CB 3.98Å; L115-A119 HydrophobicContact CB-CB 3.84Å; L115-A119 HydrophobicContact CD1-CB 4.26Å; S116-A119 WeakPolarHBondContact O-CB 3.32Å; S116-A119 PolarHBondContact O-N 2.62Å; S116-A119 VanDerWaalsContact O-N 3.11Å; S116-A119 PolarHBondContact OG-N 2.98Å; A119-K121 PolarHBondContact O-N 3.49Å; A119-V122 PolarHBondContact O-N 3.05Å; A119-V123 WeakPolarHBondContact O-CB 3.45Å; A119-V123 WeakPolarHBondContact O-CG2 3.41Å; A119-V123 PolarHBondContact O-N 3.43Å
120	C	92.5	Very high	91	Very high	1 Å²	1	39.6 Å²	39.6	1%	0.007	25%	0.246	C	C	.	.	H	α-helix	trans	-56.3	-51.9	175.2	176.6	0	0	0	0	111.3	W113 S116 A117 A118 V122 V123 R124 C191	W113-C120 HydrophobicContact CD2-CB 4.41Å; W113-C120 VanDerWaalsContact CZ2-CA 3.43Å; W113-C120 HydrophobicContact CZ2-CB 4.01Å; W113-C120 VanDerWaalsContact CZ2-N 3.31Å; S116-C120 PolarHBondContact O-N 3.43Å; A117-C120 WeakPolarHBondContact O-CB 3.34Å; A117-C120 PolarHBondContact O-N 3Å; A118-C120 VanDerWaalsContact C-N 3.32Å; A118-C120 PolarHBondContact O-N 3.49Å; C120-V122 VanDerWaalsContact C-N 3.33Å; C120-V122 PolarHBondContact O-N 3.27Å; C120-V123 PolarHBondContact O-N 2.91Å; C120-R124 WeakPolarHBondContact O-CB 3.15Å; C120-R124 VanDerWaalsContact O-CG 3.3Å; C120-R124 WeakPolarHBondContact O-CG 3.45Å; C120-R124 PolarHBondContact O-N 2.88Å; C120-C191 HydrophobicContact CB-CB 3.72Å; C120-C191 WeakPolarHBondContact CB-SG 3.43Å; C120-C191 WeakPolarHBondContact SG-CA 3.14Å; C120-C191 WeakPolarHBondContact SG-CB 3.39Å; C120-C191 CovalentContact SG-SG 2.02Å; C120-C191 PolarHBondContact SG-SG 3.15Å
121	K	93	Very high	91.6	Very high	74 Å²	74	37.4 Å²	37.4	32%	0.322	23%	0.228	S	C	.	.	H	α-helix	trans	-52.8	-48.7	177	-83.8	179.1	-178.2	-179	0	112.3	A117 A118 A119 Y125 F181 Y184 G185	A117-K121 PolarHBondContact O-N 3.4Å; A118-K121 WeakPolarHBondContact O-CB 3.08Å; A118-K121 PolarHBondContact O-N 3.32Å; A119-K121 PolarHBondContact O-N 3.49Å; K121-Y125 WeakPolarHBondContact O-CB 3.33Å; K121-Y125 PolarHBondContact O-N 3.35Å; K121-F181 HydrophobicContact CB-CD1 3.86Å; K121-F181 HydrophobicContact CB-CE1 4.19Å; K121-F181 WeakPolarHBondContact CE-O 3.16Å; K121-F181 HydrophobicContact CG-CD1 4.31Å; K121-Y184 WeakPolarHBondContact CE-O 3.4Å; K121-Y184 WeakPolarHBondContact CG-O 3.26Å; K121-G185 WeakPolarHBondContact CE-O 3.09Å
122	V	94	Very high	92.5	Very high	76 Å²	76	35.1 Å²	35.1	46%	0.461	21%	0.205	S	C	.	.	H	α-helix	trans	-65	-46.2	179.6	173.1	0	0	0	0	111.4	A118 A119 C120 Y125 L126	A118-V122 WeakPolarHBondContact O-CG2 3.48Å; A118-V122 PolarHBondContact O-N 2.87Å; A118-V122 VanDerWaalsContact O-N 3.1Å; A119-V122 PolarHBondContact O-N 3.05Å; C120-V122 VanDerWaalsContact C-N 3.33Å; C120-V122 PolarHBondContact O-N 3.27Å; V122-Y125 PolarHBondContact O-N 3.46Å; V122-L126 HydrophobicContact CG1-CD1 4.17Å; V122-L126 HydrophobicContact CG1-CG 4.46Å; V122-L126 WeakPolarHBondContact O-CG 3.46Å; V122-L126 PolarHBondContact O-N 3.47Å
123	V	94.4	Very high	93.1	Very high	4 Å²	4	28.5 Å²	28.5	2%	0.024	17%	0.174	C	C	.	.	H	α-helix	trans	-64.4	-44.6	-178.5	165.3	0	0	0	0	111.3	W100 F103 W113 A119 C120 L126 Q127	W100-V123 HydrophobicContact CB-CG1 3.92Å; W100-V123 WeakPolarHBondContact CB-O 3.41Å; F103-V123 HydrophobicContact CB-CG1 3.97Å; F103-V123 HydrophobicContact CB-CG2 3.8Å; F103-V123 HydrophobicContact CD1-CG2 4.39Å; F103-V123 HydrophobicContact CD2-CG2 3.87Å; F103-V123 HydrophobicContact CG-CG2 3.75Å; W113-V123 HydrophobicContact CH2-CB 3.93Å; W113-V123 HydrophobicContact CH2-CG1 4Å; W113-V123 HydrophobicContact CH2-CG2 3.92Å; W113-V123 HydrophobicContact CZ3-CG1 4.31Å; A119-V123 WeakPolarHBondContact O-CB 3.45Å; A119-V123 WeakPolarHBondContact O-CG2 3.41Å; A119-V123 PolarHBondContact O-N 3.43Å; C120-V123 PolarHBondContact O-N 2.91Å; V123-L126 PolarHBondContact O-N 3Å; V123-Q127 WeakPolarHBondContact O-CB 3.33Å; V123-Q127 PolarHBondContact O-N 3.43Å
124	R	92.9	Very high	93.5	Very high	0 Å²	0	27.3 Å²	27.3	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-67.3	-35.6	176.5	-65.9	-67.2	-174.4	-133.9	-9.8	112.4	C120 Q127 H128 Y184 C191 D192	C120-R124 WeakPolarHBondContact O-CB 3.15Å; C120-R124 VanDerWaalsContact O-CG 3.3Å; C120-R124 WeakPolarHBondContact O-CG 3.45Å; C120-R124 PolarHBondContact O-N 2.88Å; R124-Q127 WeakPolarHBondContact O-CB 3Å; R124-Q127 PolarHBondContact O-N 2.89Å; R124-H128 PolarHBondContact O-N 2.95Å; R124-H128 PolarHBondContact O-ND1 2.96Å; R124-Y184 HydrophobicContact CB-CD1 4.13Å; R124-Y184 HydrophobicContact CB-CD2 3.62Å; R124-Y184 HydrophobicContact CB-CE1 4.41Å; R124-Y184 HydrophobicContact CB-CE2 3.92Å; R124-Y184 HydrophobicContact CB-CG 3.71Å; R124-Y184 HydrophobicContact CG-CD1 3.61Å; R124-Y184 HydrophobicContact CG-CD2 4.07Å; R124-Y184 HydrophobicContact CG-CE1 3.91Å; R124-Y184 HydrophobicContact CG-CE2 4.33Å; R124-Y184 HydrophobicContact CG-CG 3.67Å; R124-C191 PolarHBondContact NH2-O 3.13Å; R124-D192 PolarHBondContact NE-O 3.05Å; R124-D192 VanDerWaalsContact NH2-C 3.29Å; R124-D192 PolarHBondContact NH2-O 3.37Å
125	Y	95.3	Very high	93.9	Very high	38 Å²	38	24.2 Å²	24.2	15%	0.149	15%	0.149	C	C	.	.	H	α-helix	trans	-62.9	-48.8	172	178.3	-100.8	0	0	0	111.5	K121 V122 Q127 H128 L129 A174 I177 C180 F181	K121-Y125 WeakPolarHBondContact O-CB 3.33Å; K121-Y125 PolarHBondContact O-N 3.35Å; V122-Y125 PolarHBondContact O-N 3.46Å; Y125-Q127 VanDerWaalsContact C-N 3.28Å; Y125-Q127 PolarHBondContact O-N 3.43Å; Y125-H128 PolarHBondContact O-N 3.1Å; Y125-H128 VanDerWaalsContact O-N 3.15Å; Y125-L129 HydrophobicContact CD1-CD2 4.43Å; Y125-L129 HydrophobicContact CE1-CB 4.35Å; Y125-L129 HydrophobicContact CE1-CD2 3.77Å; Y125-L129 HydrophobicContact CE1-CG 4.46Å; Y125-L129 VanDerWaalsContact O-CB 3.3Å; Y125-L129 WeakPolarHBondContact O-CB 3.31Å; Y125-L129 PolarHBondContact O-N 3.34Å; Y125-A174 VanDerWaalsContact OH-CA 3.26Å; Y125-A174 WeakPolarHBondContact OH-CA 3.47Å; Y125-A174 WeakPolarHBondContact OH-CB 3.43Å; Y125-A174 PolarHBondContact OH-O 3.08Å; Y125-A174 VanDerWaalsContact OH-O 3.1Å; Y125-I177 HydrophobicContact CD2-CB 4.41Å; Y125-I177 HydrophobicContact CD2-CG2 3.67Å; Y125-I177 HydrophobicContact CE2-CB 4Å; Y125-I177 HydrophobicContact CE2-CG2 3.77Å; Y125-C180 HydrophobicContact CD2-CB 4.37Å; Y125-F181 HydrophobicContact CD1-CE2 4.39Å; Y125-F181 AromaticContact CD1-CZ 3.79Å; Y125-F181 HydrophobicContact CD1-CZ 3.79Å; Y125-F181 HydrophobicContact CD2-CD2 4.17Å; Y125-F181 HydrophobicContact CD2-CE1 4.24Å; Y125-F181 AromaticContact CD2-CE2 3.41Å; Y125-F181 HydrophobicContact CD2-CE2 3.41Å; Y125-F181 VanDerWaalsContact CD2-CE2 3.41Å; Y125-F181 AromaticContact CD2-CZ 3.46Å; Y125-F181 HydrophobicContact CD2-CZ 3.46Å; Y125-F181 VanDerWaalsContact CD2-CZ 3.46Å; Y125-F181 HydrophobicContact CE1-CZ 4.29Å; Y125-F181 AromaticContact CE2-CE2 3.66Å; Y125-F181 HydrophobicContact CE2-CE2 3.66Å; Y125-F181 HydrophobicContact CE2-CZ 4.03Å; Y125-F181 AromaticContact CG-CE1 3.96Å; Y125-F181 HydrophobicContact CG-CE1 3.96Å; Y125-F181 AromaticContact CG-CE2 3.83Å; Y125-F181 HydrophobicContact CG-CE2 3.83Å; Y125-F181 AromaticContact CG-CZ 3.33Å; Y125-F181 HydrophobicContact CG-CZ 3.33Å
126	L	95.7	Very high	94.2	Very high	23 Å²	23	21.9 Å²	21.9	12%	0.12	14%	0.136	C	C	.	.	H	α-helix	trans	-62.5	-34.2	176.4	-69.7	179.3	0	0	0	112.9	L95 W100 V122 V123 H128 L129 C130	L95-L126 HydrophobicContact CD1-CD1 4.42Å; L95-L126 HydrophobicContact CD1-CD2 4.15Å; L95-L126 HydrophobicContact CD2-CD2 3.91Å; L95-L126 HydrophobicContact CG-CD2 4.03Å; W100-L126 HydrophobicContact CB-CB 4.22Å; V122-L126 HydrophobicContact CG1-CD1 4.17Å; V122-L126 HydrophobicContact CG1-CG 4.46Å; V122-L126 WeakPolarHBondContact O-CG 3.46Å; V122-L126 PolarHBondContact O-N 3.47Å; V123-L126 PolarHBondContact O-N 3Å; L126-H128 PolarHBondContact O-N 3.01Å; L126-L129 HydrophobicContact CD2-CD2 4.13Å; L126-C130 WeakPolarHBondContact O-CB 3.4Å; L126-C130 PolarHBondContact O-N 3.14Å; L126-C130 VanDerWaalsContact O-N 3.13Å; L126-C130 PolarHBondContact O-SG 3.38Å
127	Q	93.7	Very high	94.5	Very high	1 Å²	1	18.5 Å²	18.5	1%	0.005	11%	0.112	C	C	.	.	H	α-helix	trans	-60.2	-32.1	176.2	-174.2	-177.9	-26.9	0	0	112.4	W100 V123 R124 Y125 P131 F273	W100-Q127 HydrophobicContact CB-CB 4.32Å; W100-Q127 HydrophobicContact CD2-CB 4.17Å; W100-Q127 HydrophobicContact CD2-CG 4.15Å; W100-Q127 HydrophobicContact CE3-CG 4.2Å; W100-Q127 HydrophobicContact CG-CB 4.06Å; V123-Q127 WeakPolarHBondContact O-CB 3.33Å; V123-Q127 PolarHBondContact O-N 3.43Å; R124-Q127 WeakPolarHBondContact O-CB 3Å; R124-Q127 PolarHBondContact O-N 2.89Å; Y125-Q127 VanDerWaalsContact C-N 3.28Å; Y125-Q127 PolarHBondContact O-N 3.43Å; Q127-P131 WeakPolarHBondContact O-CD 3.46Å; Q127-P131 VanDerWaalsContact O-CG 3.23Å; Q127-P131 WeakPolarHBondContact O-CG 3.34Å; Q127-F273 HydrophobicContact CG-CE2 4.36Å; Q127-F273 HydrophobicContact CG-CZ 4.02Å
128	H	94.3	Very high	94.8	Very high	7 Å²	7	16.9 Å²	16.9	3%	0.032	10%	0.098	C	C	.	.	H	α-helix	trans	-95	-39.7	178.1	-68.6	86.7	0	0	0	112.9	R124 Y125 L126 P131 G132 I177 H208	R124-H128 PolarHBondContact O-N 2.95Å; R124-H128 PolarHBondContact O-ND1 2.96Å; Y125-H128 PolarHBondContact O-N 3.1Å; Y125-H128 VanDerWaalsContact O-N 3.15Å; L126-H128 PolarHBondContact O-N 3.01Å; H128-P131 WeakPolarHBondContact O-CD 3.3Å; H128-P131 WeakPolarHBondContact O-CG 3.17Å; H128-G132 PolarHBondContact O-N 3.33Å; H128-I177 HydrophobicContact CB-CD1 4.05Å; H128-I177 HydrophobicContact CB-CG1 4.33Å; H128-I177 HydrophobicContact CB-CG2 3.51Å; H128-H208 AromaticContact CD2-ND1 3.99Å
129	L	96.7	Very high	95	Very high	11 Å²	11	15.3 Å²	15.3	6%	0.058	8%	0.081	C	C	.	.	H	α-helix	trans	-60.4	-51.8	-179.8	177.2	74.3	0	0	0	112	Y125 L126 G132 V133 D173 A174	Y125-L129 HydrophobicContact CD1-CD2 4.43Å; Y125-L129 HydrophobicContact CE1-CB 4.35Å; Y125-L129 HydrophobicContact CE1-CD2 3.77Å; Y125-L129 HydrophobicContact CE1-CG 4.46Å; Y125-L129 VanDerWaalsContact O-CB 3.3Å; Y125-L129 WeakPolarHBondContact O-CB 3.31Å; Y125-L129 PolarHBondContact O-N 3.34Å; L126-L129 HydrophobicContact CD2-CD2 4.13Å; L129-G132 PolarHBondContact O-N 2.99Å; L129-V133 HydrophobicContact CD1-CG2 3.92Å; L129-V133 HydrophobicContact CG-CG2 4.11Å; L129-V133 WeakPolarHBondContact O-CB 3.38Å; L129-V133 WeakPolarHBondContact O-CG2 3.15Å; L129-V133 PolarHBondContact O-N 2.88Å; L129-D173 WeakPolarHBondContact CA-OD2 3.32Å; L129-D173 HydrophobicContact CD1-CB 4.48Å; L129-A174 HydrophobicContact CD1-CB 3.9Å
130	C	95.9	Very high	95.1	Very high	0 Å²	0	14.6 Å²	14.6	0%	0	7%	0.074	C	C	.	.	H	α-helix	trans	-62.6	-45	-171.4	-65	0	0	0	0	114.2	L95 M96 L126 Q134	L95-C130 VanDerWaalsContact CG-SG 3.58Å; M96-C130 HydrophobicContact CB-CB 4.4Å; M96-C130 HydrophobicContact CG-CB 3.07Å; M96-C130 HydrophobicContact SD-CB 3.77Å; L126-C130 WeakPolarHBondContact O-CB 3.4Å; L126-C130 PolarHBondContact O-N 3.14Å; L126-C130 VanDerWaalsContact O-N 3.13Å; L126-C130 PolarHBondContact O-SG 3.38Å; C130-Q134 VanDerWaalsContact O-CG 3.32Å; C130-Q134 WeakPolarHBondContact O-CG 3.25Å; C130-Q134 PolarHBondContact O-N 2.93Å; C130-Q134 PolarHBondContact O-NE2 2.87Å
131	P	94.7	Very high	95.1	Very high	0 Å²	0	14.6 Å²	14.6	0%	0	7%	0.074	C	C	.	.	H	α-helix	trans	-66.5	-37	171.9	26	-34.4	0	0	0	112.8	Q127 H128 Q134 V135 F266 W270	Q127-P131 WeakPolarHBondContact O-CD 3.46Å; Q127-P131 VanDerWaalsContact O-CG 3.23Å; Q127-P131 WeakPolarHBondContact O-CG 3.34Å; H128-P131 WeakPolarHBondContact O-CD 3.3Å; H128-P131 WeakPolarHBondContact O-CG 3.17Å; P131-Q134 WeakPolarHBondContact O-CB 3.38Å; P131-Q134 PolarHBondContact O-N 3.39Å; P131-V135 WeakPolarHBondContact O-CG2 3.39Å; P131-V135 PolarHBondContact O-N 2.94Å; P131-F266 HydrophobicContact CB-CZ 4.15Å; P131-F266 WeakPolarHBondContact O-CZ 3.24Å; P131-W270 HydrophobicContact CB-CD2 3.85Å; P131-W270 HydrophobicContact CB-CE3 3.6Å; P131-W270 HydrophobicContact CB-CH2 3.6Å; P131-W270 HydrophobicContact CB-CZ2 3.84Å; P131-W270 HydrophobicContact CB-CZ3 3.49Å; P131-W270 VanDerWaalsContact CB-CZ3 3.49Å; P131-W270 HydrophobicContact CG-CE3 4.01Å; P131-W270 HydrophobicContact CG-CH2 3.66Å; P131-W270 HydrophobicContact CG-CZ2 4.38Å; P131-W270 HydrophobicContact CG-CZ3 3.46Å; P131-W270 VanDerWaalsContact CG-CZ3 3.46Å
132	G	95.9	Very high	95.1	Very high	2 Å²	2	11 Å²	11	2%	0.021	6%	0.059	C	C	.	.	H	α-helix	trans	-59.8	-50.9	176.5	0	0	0	0	0	112.3	H128 L129 Q134 V135 Y136 D173	H128-G132 PolarHBondContact O-N 3.33Å; L129-G132 PolarHBondContact O-N 2.99Å; G132-Q134 PolarHBondContact O-N 2.88Å; G132-V135 WeakPolarHBondContact O-CA 3.47Å; G132-V135 WeakPolarHBondContact O-CB 3.43Å; G132-V135 PolarHBondContact O-N 3.5Å; G132-Y136 WeakPolarHBondContact O-CD2 3.35Å; G132-Y136 PolarHBondContact O-N 2.89Å; G132-Y136 VanDerWaalsContact O-N 3.08Å; G132-D173 VanDerWaalsContact C-CG 3.41Å; G132-D173 VanDerWaalsContact C-OD2 3.25Å; G132-D173 WeakPolarHBondContact CA-OD1 3.14Å; G132-D173 VanDerWaalsContact CA-OD2 3.31Å; G132-D173 WeakPolarHBondContact CA-OD2 3.48Å
133	V	97	Very high	95	Very high	0 Å²	0	9 Å²	9	0%	0	5%	0.046	C	C	.	.	H	α-helix	trans	-52.7	-42.6	173.4	169.1	0	0	0	0	111.6	A92 L129 V135 Y136 V137 W170 D173	A92-V133 HydrophobicContact CB-CG1 4.32Å; L129-V133 HydrophobicContact CD1-CG2 3.92Å; L129-V133 HydrophobicContact CG-CG2 4.11Å; L129-V133 WeakPolarHBondContact O-CB 3.38Å; L129-V133 WeakPolarHBondContact O-CG2 3.15Å; L129-V133 PolarHBondContact O-N 2.88Å; V133-V135 PolarHBondContact O-N 3.28Å; V133-Y136 PolarHBondContact O-N 3.33Å; V133-V137 HydrophobicContact CG1-CG2 4.15Å; V133-V137 WeakPolarHBondContact O-CB 3.39Å; V133-V137 WeakPolarHBondContact O-CG2 3.36Å; V133-V137 PolarHBondContact O-N 2.8Å; V133-W170 HydrophobicContact CG1-CD2 3.69Å; V133-W170 VanDerWaalsContact CG1-CE2 3.44Å; V133-W170 HydrophobicContact CG1-CE3 4.24Å; V133-W170 HydrophobicContact CG1-CG 4.02Å; V133-W170 HydrophobicContact CG1-CH2 4.35Å; V133-W170 HydrophobicContact CG1-CZ2 3.81Å; V133-W170 HydrophobicContact CG2-CD2 4.02Å; V133-W170 HydrophobicContact CG2-CE3 3.91Å; V133-W170 HydrophobicContact CG2-CG 4.37Å; V133-W170 HydrophobicContact CG2-CZ3 4.37Å; V133-D173 HydrophobicContact CG2-CB 3.93Å; V133-D173 PolarHBondContact N-OD2 2.82Å
134	Q	96.3	Very high	94.7	Very high	1 Å²	1	8.8 Å²	8.8	1%	0.005	5%	0.045	C	C	.	.	H	α-helix	trans	-63.3	-40.9	177.8	-71	167.2	73.2	0	0	112.3	A92 D93 M96 C130 P131 G132 V137 L138 F266	A92-Q134 HydrophobicContact CB-CG 3.91Å; D93-Q134 PolarHBondContact OD1-OE1 2.98Å; M96-Q134 PolarHBondContact SD-NE2 3.46Å; C130-Q134 VanDerWaalsContact O-CG 3.32Å; C130-Q134 WeakPolarHBondContact O-CG 3.25Å; C130-Q134 PolarHBondContact O-N 2.93Å; C130-Q134 PolarHBondContact O-NE2 2.87Å; P131-Q134 WeakPolarHBondContact O-CB 3.38Å; P131-Q134 PolarHBondContact O-N 3.39Å; G132-Q134 PolarHBondContact O-N 2.88Å; Q134-V137 PolarHBondContact O-N 3.29Å; Q134-L138 WeakPolarHBondContact O-CB 3.35Å; Q134-L138 WeakPolarHBondContact O-CG 3.49Å; Q134-L138 PolarHBondContact O-N 3Å; Q134-F266 HydrophobicContact CB-CD2 4.48Å; Q134-F266 HydrophobicContact CB-CE2 3.75Å; Q134-F266 HydrophobicContact CB-CZ 3.93Å; Q134-F266 HydrophobicContact CG-CE2 4.37Å
135	V	96.4	Very high	94.5	Very high	0 Å²	0	9.9 Å²	9.9	0%	0	5%	0.049	C	C	.	.	H	α-helix	trans	-57.9	-50.2	174.8	174.8	0	0	0	0	110.7	P131 G132 V133 V137 L138 L139 F213 P216 F266 F267	P131-V135 WeakPolarHBondContact O-CG2 3.39Å; P131-V135 PolarHBondContact O-N 2.94Å; G132-V135 WeakPolarHBondContact O-CA 3.47Å; G132-V135 WeakPolarHBondContact O-CB 3.43Å; G132-V135 PolarHBondContact O-N 3.5Å; V133-V135 PolarHBondContact O-N 3.28Å; V135-V137 PolarHBondContact O-N 3.31Å; V135-L138 WeakPolarHBondContact O-CB 3.28Å; V135-L138 PolarHBondContact O-N 3.09Å; V135-L139 PolarHBondContact O-N 3.42Å; V135-F213 HydrophobicContact CG2-CD2 4.38Å; V135-P216 HydrophobicContact CG1-CB 3.22Å; V135-P216 HydrophobicContact CG1-CG 3.73Å; V135-F266 HydrophobicContact CG2-CD1 4.46Å; V135-F266 HydrophobicContact CG2-CE1 3.41Å; V135-F266 VanDerWaalsContact CG2-CE1 3.41Å; V135-F266 HydrophobicContact CG2-CZ 3.89Å; V135-F267 HydrophobicContact CG1-CE1 4.38Å; V135-F267 HydrophobicContact CG2-CE1 4.1Å
136	Y	96.8	Very high	94.1	Very high	21 Å²	21	8.7 Å²	8.7	8%	0.082	5%	0.045	C	C	.	.	H	α-helix	trans	-70.3	-31.5	-178.7	-68	-68.5	0	0	0	113.1	G132 V133 L139 S140 S169 F172 D173 V211 P216	G132-Y136 WeakPolarHBondContact O-CD2 3.35Å; G132-Y136 PolarHBondContact O-N 2.89Å; G132-Y136 VanDerWaalsContact O-N 3.08Å; V133-Y136 PolarHBondContact O-N 3.33Å; Y136-L139 HydrophobicContact CD1-CD2 4.43Å; Y136-L139 PolarHBondContact O-N 2.91Å; Y136-S140 WeakPolarHBondContact O-CB 3.3Å; Y136-S140 PolarHBondContact O-N 3.46Å; Y136-S140 PolarHBondContact O-OG 3.43Å; Y136-S140 VanDerWaalsContact O-OG 3.07Å; Y136-S169 PolarHBondContact O-OG 3.03Å; Y136-F172 HydrophobicContact CD1-CD1 4.26Å; Y136-F172 HydrophobicContact CD1-CE1 4.45Å; Y136-F172 HydrophobicContact CD2-CD1 4.28Å; Y136-F172 AromaticContact CE1-CD1 3.91Å; Y136-F172 HydrophobicContact CE1-CD1 3.91Å; Y136-F172 AromaticContact CE1-CE1 3.66Å; Y136-F172 HydrophobicContact CE1-CE1 3.66Å; Y136-F172 AromaticContact CE2-CD1 3.94Å; Y136-F172 HydrophobicContact CE2-CD1 3.94Å; Y136-F172 AromaticContact CE2-CE1 3.98Å; Y136-F172 HydrophobicContact CE2-CE1 3.98Å; Y136-F172 HydrophobicContact CG-CD1 4.45Å; Y136-F172 AromaticContact CZ-CD1 3.76Å; Y136-F172 AromaticContact CZ-CE1 3.41Å; Y136-F172 VanDerWaalsContact CZ-CE1 3.41Å; Y136-F172 WeakPolarHBondContact OH-CE1 3.47Å; Y136-D173 HydrophobicContact CD2-CB 3.85Å; Y136-D173 HydrophobicContact CE2-CB 4.14Å; Y136-D173 VanDerWaalsContact CE2-OD1 3.29Å; Y136-D173 WeakPolarHBondContact CE2-OD1 3.29Å; Y136-V211 PolarHBondContact OH-O 3Å; Y136-P216 HydrophobicContact CE1-CG 4.04Å
137	V	96.3	Very high	93.7	Very high	1 Å²	1	12 Å²	12	1%	0.006	6%	0.056	C	C	.	.	H	α-helix	trans	-68.8	-39.3	171.3	171.7	0	0	0	0	111.2	F85 M89 V133 Q134 V135 L139 S140 I141	F85-V137 HydrophobicContact CB-CG1 4.14Å; F85-V137 HydrophobicContact CD1-CG1 4.18Å; M89-V137 HydrophobicContact CG-CB 4.41Å; M89-V137 HydrophobicContact CG-CG1 3.69Å; M89-V137 HydrophobicContact SD-CG1 4.42Å; V133-V137 HydrophobicContact CG1-CG2 4.15Å; V133-V137 WeakPolarHBondContact O-CB 3.39Å; V133-V137 WeakPolarHBondContact O-CG2 3.36Å; V133-V137 PolarHBondContact O-N 2.8Å; Q134-V137 PolarHBondContact O-N 3.29Å; V135-V137 PolarHBondContact O-N 3.31Å; V137-L139 VanDerWaalsContact C-N 3.35Å; V137-S140 WeakPolarHBondContact O-CB 3.47Å; V137-S140 PolarHBondContact O-N 3.03Å; V137-I141 HydrophobicContact CG1-CD1 4.24Å; V137-I141 VanDerWaalsContact O-CG1 3.32Å; V137-I141 WeakPolarHBondContact O-CG1 3.38Å; V137-I141 PolarHBondContact O-N 2.92Å
138	L	94.5	Very high	93.1	Very high	4 Å²	4	13.1 Å²	13.1	2%	0.021	6%	0.063	C	C	.	.	H	α-helix	trans	-64.1	-39.8	173.2	-74.9	171.1	0	0	0	111.8	M89 Q134 V135 I141 S142 I220 N263 F266	M89-L138 HydrophobicContact SD-CD2 3.84Å; M89-L138 HydrophobicContact SD-CG 4.29Å; Q134-L138 WeakPolarHBondContact O-CB 3.35Å; Q134-L138 WeakPolarHBondContact O-CG 3.49Å; Q134-L138 PolarHBondContact O-N 3Å; V135-L138 WeakPolarHBondContact O-CB 3.28Å; V135-L138 PolarHBondContact O-N 3.09Å; L138-I141 HydrophobicContact CD2-CD1 4.28Å; L138-I141 WeakPolarHBondContact O-CB 3.45Å; L138-I141 PolarHBondContact O-N 2.84Å; L138-S142 PolarHBondContact O-N 2.99Å; L138-I220 HydrophobicContact CB-CD1 4.09Å; L138-N263 WeakPolarHBondContact CB-OD1 3.39Å; L138-F266 HydrophobicContact CD1-CB 4.21Å; L138-F266 HydrophobicContact CD1-CD1 3.97Å; L138-F266 HydrophobicContact CD1-CG 4.02Å
139	L	95.6	Very high	92.5	Very high	30 Å²	30	13 Å²	13	16%	0.157	6%	0.063	C	C	.	.	H	α-helix	trans	-60.2	-48	171.4	178.5	61.8	0	0	0	110.8	V135 Y136 V137 I141 S142 V143 L219 I220 F223	V135-L139 PolarHBondContact O-N 3.42Å; Y136-L139 HydrophobicContact CD1-CD2 4.43Å; Y136-L139 PolarHBondContact O-N 2.91Å; V137-L139 VanDerWaalsContact C-N 3.35Å; L139-I141 VanDerWaalsContact C-N 3.29Å; L139-I141 PolarHBondContact O-N 3.26Å; L139-S142 WeakPolarHBondContact O-CB 3.46Å; L139-S142 PolarHBondContact O-N 2.97Å; L139-S142 PolarHBondContact O-OG 2.96Å; L139-V143 WeakPolarHBondContact O-CG2 3.32Å; L139-V143 PolarHBondContact O-N 2.98Å; L139-L219 HydrophobicContact CD1-CB 3.73Å; L139-L219 HydrophobicContact CD1-CD1 4.41Å; L139-L219 HydrophobicContact CD2-CD1 4.3Å; L139-I220 HydrophobicContact CB-CD1 4.13Å; L139-I220 HydrophobicContact CB-CG1 4.07Å; L139-I220 HydrophobicContact CD1-CG1 3.89Å; L139-F223 HydrophobicContact CD1-CD2 4.21Å; L139-F223 HydrophobicContact CD1-CE2 4.08Å
140	S	94.8	Very high	91.9	Very high	13 Å²	13	13.3 Å²	13.3	9%	0.091	7%	0.065	C	C	.	.	H	α-helix	trans	-56.5	-41.3	175.1	-72.6	0	0	0	0	112.7	Y136 V137 V143 D144 M165 S169	Y136-S140 WeakPolarHBondContact O-CB 3.3Å; Y136-S140 PolarHBondContact O-N 3.46Å; Y136-S140 PolarHBondContact O-OG 3.43Å; Y136-S140 VanDerWaalsContact O-OG 3.07Å; V137-S140 WeakPolarHBondContact O-CB 3.47Å; V137-S140 PolarHBondContact O-N 3.03Å; S140-V143 PolarHBondContact O-N 2.84Å; S140-D144 WeakPolarHBondContact O-CB 3.28Å; S140-D144 PolarHBondContact O-N 3.3Å; S140-M165 VanDerWaalsContact O-CE 3.25Å; S140-M165 WeakPolarHBondContact O-CE 3.22Å; S140-S169 PolarHBondContact OG-OG 3.46Å
141	I	92.7	Very high	91.2	Very high	0 Å²	0	18.4 Å²	18.4	0%	0	9%	0.085	C	C	.	.	H	α-helix	trans	-61.7	-46.1	173.1	-70.6	161.3	0	0	0	110.7	F85 M89 V137 L138 L139 V143 D144 R145 F259	F85-I141 HydrophobicContact CB-CD1 3.73Å; F85-I141 HydrophobicContact CB-CG1 3.5Å; F85-I141 VanDerWaalsContact CB-CG1 3.5Å; F85-I141 HydrophobicContact CD1-CG1 4.2Å; F85-I141 HydrophobicContact CD2-CG1 3.89Å; F85-I141 HydrophobicContact CG-CD1 4.39Å; F85-I141 HydrophobicContact CG-CG1 3.63Å; M89-I141 HydrophobicContact CE-CD1 3.45Å; M89-I141 VanDerWaalsContact CE-CD1 3.45Å; M89-I141 HydrophobicContact SD-CD1 4Å; V137-I141 HydrophobicContact CG1-CD1 4.24Å; V137-I141 VanDerWaalsContact O-CG1 3.32Å; V137-I141 WeakPolarHBondContact O-CG1 3.38Å; V137-I141 PolarHBondContact O-N 2.92Å; L138-I141 HydrophobicContact CD2-CD1 4.28Å; L138-I141 WeakPolarHBondContact O-CB 3.45Å; L138-I141 PolarHBondContact O-N 2.84Å; L139-I141 VanDerWaalsContact C-N 3.29Å; L139-I141 PolarHBondContact O-N 3.26Å; I141-V143 VanDerWaalsContact C-N 3.28Å; I141-V143 PolarHBondContact O-N 2.99Å; I141-D144 PolarHBondContact O-N 2.9Å; I141-R145 HydrophobicContact CG2-CG 4.15Å; I141-R145 WeakPolarHBondContact O-CB 3.49Å; I141-R145 VanDerWaalsContact O-CG 3.28Å; I141-R145 WeakPolarHBondContact O-CG 3.31Å; I141-R145 PolarHBondContact O-N 3.1Å; I141-F259 HydrophobicContact CD1-CD1 4.42Å; I141-F259 HydrophobicContact CD1-CE1 3.97Å; I141-F259 HydrophobicContact CG1-CE1 4.42Å; I141-F259 HydrophobicContact CG2-CD1 3.65Å; I141-F259 HydrophobicContact CG2-CD2 3.81Å; I141-F259 HydrophobicContact CG2-CE1 3.56Å; I141-F259 HydrophobicContact CG2-CE2 3.69Å; I141-F259 HydrophobicContact CG2-CG 3.76Å; I141-F259 HydrophobicContact CG2-CZ 3.54Å
142	S	92.2	Very high	90	Very high	0 Å²	0	21.5 Å²	21.5	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-60.6	-39.4	-179	78.3	0	0	0	0	111.9	L138 L139 R145 F146 F223	L138-S142 PolarHBondContact O-N 2.99Å; L139-S142 WeakPolarHBondContact O-CB 3.46Å; L139-S142 PolarHBondContact O-N 2.97Å; L139-S142 PolarHBondContact O-OG 2.96Å; S142-R145 PolarHBondContact O-N 3.08Å; S142-F146 WeakPolarHBondContact O-CB 3.48Å; S142-F146 PolarHBondContact O-N 3.21Å; S142-F223 WeakPolarHBondContact OG-CD2 3.36Å
143	V	92.1	Very high	88.7	Confident	33 Å²	33	29.8 Å²	29.8	20%	0.2	15%	0.148	C	C	.	.	H	α-helix	trans	-65.1	-48.8	174.8	173.3	0	0	0	0	111.1	L139 S140 I141 R145 F146 Y147 M165 F223	L139-V143 WeakPolarHBondContact O-CG2 3.32Å; L139-V143 PolarHBondContact O-N 2.98Å; S140-V143 PolarHBondContact O-N 2.84Å; I141-V143 VanDerWaalsContact C-N 3.28Å; I141-V143 PolarHBondContact O-N 2.99Å; V143-R145 VanDerWaalsContact C-N 3.3Å; V143-R145 PolarHBondContact O-N 2.86Å; V143-F146 WeakPolarHBondContact O-CB 3.5Å; V143-F146 PolarHBondContact O-N 3.21Å; V143-Y147 HydrophobicContact CG1-CD2 3.81Å; V143-Y147 HydrophobicContact CG1-CE2 3.76Å; V143-Y147 WeakPolarHBondContact O-CD2 3.21Å; V143-Y147 PolarHBondContact O-N 2.87Å; V143-M165 HydrophobicContact CB-CE 4.18Å; V143-M165 HydrophobicContact CG1-CE 4.15Å; V143-F223 HydrophobicContact CG2-CD2 4.2Å; V143-F223 HydrophobicContact CG2-CE1 4.46Å; V143-F223 HydrophobicContact CG2-CE2 3.7Å; V143-F223 HydrophobicContact CG2-CZ 3.86Å
144	D	88.8	Confident	87.1	Confident	0 Å²	0	33.2 Å²	33.2	0%	0	17%	0.172	C	C	.	.	H	α-helix	trans	-59.9	-40.1	177.3	159.2	87.6	0	0	0	112	T81 F85 S140 I141 T148 V157	T81-D144 PolarHBondContact OG1-OD1 3.49Å; F85-D144 HydrophobicContact CE2-CB 3.97Å; F85-D144 HydrophobicContact CZ-CB 4.37Å; S140-D144 WeakPolarHBondContact O-CB 3.28Å; S140-D144 PolarHBondContact O-N 3.3Å; I141-D144 PolarHBondContact O-N 2.9Å; D144-T148 WeakPolarHBondContact O-CB 3.32Å; D144-T148 PolarHBondContact O-N 3.28Å; D144-T148 PolarHBondContact O-OG1 3.07Å; D144-V157 HydrophobicContact CB-CG2 4.12Å; D144-V157 WeakPolarHBondContact OD1-CB 3.42Å
145	R	87.9	Confident	85.6	Confident	22 Å²	22	38.9 Å²	38.9	8%	0.083	20%	0.197	C	C	.	.	H	α-helix	trans	-66.2	-44.5	174.5	-70.1	-53.1	95.5	-174.3	2	112	T82 I141 S142 V143 T148 I149 F259	T82-R145 PolarHBondContact OG1-NH2 3.18Å; I141-R145 HydrophobicContact CG2-CG 4.15Å; I141-R145 WeakPolarHBondContact O-CB 3.49Å; I141-R145 VanDerWaalsContact O-CG 3.28Å; I141-R145 WeakPolarHBondContact O-CG 3.31Å; I141-R145 PolarHBondContact O-N 3.1Å; S142-R145 PolarHBondContact O-N 3.08Å; V143-R145 VanDerWaalsContact C-N 3.3Å; V143-R145 PolarHBondContact O-N 2.86Å; R145-T148 PolarHBondContact O-N 2.94Å; R145-I149 HydrophobicContact CB-CD1 4.28Å; R145-I149 WeakPolarHBondContact O-CB 3.46Å; R145-I149 WeakPolarHBondContact O-CD1 3.36Å; R145-I149 VanDerWaalsContact O-CG1 3.3Å; R145-I149 WeakPolarHBondContact O-CG1 3.35Å; R145-I149 PolarHBondContact O-N 3.2Å; R145-I149 VanDerWaalsContact O-N 3.07Å; R145-F259 HydrophobicContact CG-CD2 3.93Å; R145-F259 HydrophobicContact CG-CE2 3.98Å
146	F	88	Confident	84.4	Confident	14 Å²	14	47.4 Å²	47.4	6%	0.061	23%	0.234	C	C	.	.	H	α-helix	trans	-55.3	-55.1	177.7	173.8	-103	0	0	0	111.3	S142 V143 T148 I149 V150 Y151 F223 R226 V227	S142-F146 WeakPolarHBondContact O-CB 3.48Å; S142-F146 PolarHBondContact O-N 3.21Å; V143-F146 WeakPolarHBondContact O-CB 3.5Å; V143-F146 PolarHBondContact O-N 3.21Å; F146-T148 PolarHBondContact O-N 3.29Å; F146-I149 PolarHBondContact O-N 3.39Å; F146-V150 HydrophobicContact CD2-CB 4.36Å; F146-V150 HydrophobicContact CD2-CG2 3.75Å; F146-V150 HydrophobicContact CE2-CB 4.18Å; F146-V150 HydrophobicContact CE2-CG1 4.25Å; F146-V150 HydrophobicContact CE2-CG2 3.82Å; F146-V150 HydrophobicContact CZ-CG1 4.48Å; F146-V150 VanDerWaalsContact O-CB 3.28Å; F146-V150 WeakPolarHBondContact O-CB 3.44Å; F146-V150 WeakPolarHBondContact O-CG2 3.44Å; F146-V150 PolarHBondContact O-N 3.38Å; F146-Y151 HydrophobicContact CE1-CD2 4.23Å; F146-Y151 AromaticContact CE1-CE2 3.78Å; F146-Y151 HydrophobicContact CE1-CE2 3.78Å; F146-Y151 HydrophobicContact CZ-CD2 4.47Å; F146-Y151 AromaticContact CZ-CE2 3.73Å; F146-Y151 HydrophobicContact CZ-CE2 3.73Å; F146-F223 HydrophobicContact CB-CD1 3.95Å; F146-F223 HydrophobicContact CD1-CD1 4.14Å; F146-F223 HydrophobicContact CD1-CE1 4.22Å; F146-F223 HydrophobicContact CD2-CD1 4.18Å; F146-F223 AromaticContact CG-CD1 3.82Å; F146-F223 HydrophobicContact CG-CD1 3.82Å; F146-F223 HydrophobicContact CG-CE1 4.36Å; F146-R226 HydrophobicContact CD2-CB 4.11Å; F146-R226 HydrophobicContact CE2-CB 3.81Å; F146-R226 HydrophobicContact CE2-CG 4.5Å; F146-V227 HydrophobicContact CB-CG2 4.15Å; F146-V227 HydrophobicContact CD2-CG2 4.17Å
147	Y	86.8	Confident	83.6	Confident	92 Å²	92	47.1 Å²	47.1	36%	0.361	24%	0.235	S	C	.	.	H	α-helix	trans	-64.9	-42.4	-179.9	-75.8	-70	0	0	0	112.9	V143 I149 Y151 F155	V143-Y147 HydrophobicContact CG1-CD2 3.81Å; V143-Y147 HydrophobicContact CG1-CE2 3.76Å; V143-Y147 WeakPolarHBondContact O-CD2 3.21Å; V143-Y147 PolarHBondContact O-N 2.87Å; Y147-I149 PolarHBondContact O-N 3Å; Y147-Y151 AromaticContact CD1-CD2 3.96Å; Y147-Y151 HydrophobicContact CD1-CD2 3.96Å; Y147-Y151 HydrophobicContact CE1-CD2 4.38Å; Y147-Y151 CarbonylContact O-C 3.47Å; Y147-Y151 VanDerWaalsContact O-C 3.28Å; Y147-Y151 WeakPolarHBondContact O-CA 3.36Å; Y147-Y151 PolarHBondContact O-N 3.37Å; Y147-F155 HydrophobicContact CD1-CB 3.97Å; Y147-F155 HydrophobicContact CD1-CG 4.44Å; Y147-F155 HydrophobicContact CG-CB 4.49Å
148	T	82.3	Confident	83.1	Confident	24 Å²	24	49.5 Å²	49.5	15%	0.147	25%	0.251	C	S	.	.	H	α-helix	trans	-67.3	-22.8	-177.9	-60.6	0	0	0	0	113.9	D144 R145 F146 K252	D144-T148 WeakPolarHBondContact O-CB 3.32Å; D144-T148 PolarHBondContact O-N 3.28Å; D144-T148 PolarHBondContact O-OG1 3.07Å; R145-T148 PolarHBondContact O-N 2.94Å; F146-T148 PolarHBondContact O-N 3.29Å; T148-K252 PolarHBondContact O-NZ 3.5Å
149	I	80.9	Confident	82.7	Confident	4 Å²	4	55.3 Å²	55.3	2%	0.021	27%	0.273	C	S	.	.	H	α-helix	trans	-103.4	-49.3	-176.2	-64.4	161.6	0	0	0	111.3	R145 F146 Y147 V227 Y230 I231 K252 I256	R145-I149 HydrophobicContact CB-CD1 4.28Å; R145-I149 WeakPolarHBondContact O-CB 3.46Å; R145-I149 WeakPolarHBondContact O-CD1 3.36Å; R145-I149 VanDerWaalsContact O-CG1 3.3Å; R145-I149 WeakPolarHBondContact O-CG1 3.35Å; R145-I149 PolarHBondContact O-N 3.2Å; R145-I149 VanDerWaalsContact O-N 3.07Å; F146-I149 PolarHBondContact O-N 3.39Å; Y147-I149 PolarHBondContact O-N 3Å; I149-V227 HydrophobicContact CB-CG1 4.47Å; I149-V227 HydrophobicContact CD1-CG1 3.74Å; I149-V227 HydrophobicContact CG2-CG1 4.18Å; I149-Y230 HydrophobicContact CG2-CD1 4.06Å; I149-Y230 HydrophobicContact CG2-CE1 4.31Å; I149-Y230 WeakPolarHBondContact O-CE1 3.23Å; I149-I231 HydrophobicContact CG2-CD1 4.29Å; I149-I231 HydrophobicContact CG2-CG1 4.18Å; I149-K252 HydrophobicContact CG1-CD 4.49Å; I149-I256 HydrophobicContact CD1-CD1 3.39Å; I149-I256 HydrophobicContact CD1-CG1 3.66Å
150	V	83.3	Confident	82.4	Confident	19 Å²	19	58.8 Å²	58.8	12%	0.115	29%	0.288	C	S	.	.	H	α-helix	trans	-77.6	-31.1	-175.9	-177.7	0	0	0	0	111.2	F146 P152 V227 Y230	F146-V150 HydrophobicContact CD2-CB 4.36Å; F146-V150 HydrophobicContact CD2-CG2 3.75Å; F146-V150 HydrophobicContact CE2-CB 4.18Å; F146-V150 HydrophobicContact CE2-CG1 4.25Å; F146-V150 HydrophobicContact CE2-CG2 3.82Å; F146-V150 HydrophobicContact CZ-CG1 4.48Å; F146-V150 VanDerWaalsContact O-CB 3.28Å; F146-V150 WeakPolarHBondContact O-CB 3.44Å; F146-V150 WeakPolarHBondContact O-CG2 3.44Å; F146-V150 PolarHBondContact O-N 3.38Å; V150-P152 WeakPolarHBondContact O-CD 3.36Å; V150-V227 HydrophobicContact CG2-CG2 4.3Å; V150-Y230 HydrophobicContact CB-CD2 4.48Å; V150-Y230 HydrophobicContact CB-CG 4.41Å; V150-Y230 HydrophobicContact CG1-CD2 3.94Å; V150-Y230 HydrophobicContact CG1-CE2 4.19Å; V150-Y230 HydrophobicContact CG1-CG 4.3Å; V150-Y230 HydrophobicContact CG2-CD1 4.24Å; V150-Y230 HydrophobicContact CG2-CD2 4.5Å; V150-Y230 HydrophobicContact CG2-CG 4.03Å; V150-Y230 PolarHBondContact O-OH 3.18Å
151	Y	81.4	Confident	82.2	Confident	107 Å²	107	63.7 Å²	63.7	42%	0.42	31%	0.308	S	S	.	.	S	Bend	trans	-125.6	57.6	-176.8	-63.1	-69.6	0	0	0	112.5	F146 Y147 L153 S154 F155	F146-Y151 HydrophobicContact CE1-CD2 4.23Å; F146-Y151 AromaticContact CE1-CE2 3.78Å; F146-Y151 HydrophobicContact CE1-CE2 3.78Å; F146-Y151 HydrophobicContact CZ-CD2 4.47Å; F146-Y151 AromaticContact CZ-CE2 3.73Å; F146-Y151 HydrophobicContact CZ-CE2 3.73Å; Y147-Y151 AromaticContact CD1-CD2 3.96Å; Y147-Y151 HydrophobicContact CD1-CD2 3.96Å; Y147-Y151 HydrophobicContact CE1-CD2 4.38Å; Y147-Y151 CarbonylContact O-C 3.47Å; Y147-Y151 VanDerWaalsContact O-C 3.28Å; Y147-Y151 WeakPolarHBondContact O-CA 3.36Å; Y147-Y151 PolarHBondContact O-N 3.37Å; Y151-L153 PolarHBondContact O-N 2.91Å; Y151-L153 VanDerWaalsContact O-N 3.13Å; Y151-S154 PolarHBondContact O-N 3.35Å; Y151-F155 PolarHBondContact O-N 3.19Å
152	P	70.2	Confident	82.2	Confident	65 Å²	65	63.7 Å²	63.7	42%	0.422	31%	0.308	S	S	.	.	T	Hydrogen-bonded Turn	trans	-65.2	-21.7	-168.5	27.4	-35.3	0	0	0	114.7	V150	V150-P152 WeakPolarHBondContact O-CD 3.36Å
153	L	67.8	Low	82.2	Confident	176 Å²	176	67.6 Å²	67.6	92%	0.921	33%	0.325	S	S	*	.	T	Hydrogen-bonded Turn	trans	-105.1	-13.9	-175.5	-64.6	173.6	0	0	0	114.2	Y151	Y151-L153 PolarHBondContact O-N 2.91Å; Y151-L153 VanDerWaalsContact O-N 3.13Å
154	S	63.3	Low	82.4	Confident	72 Å²	72	73.1 Å²	73.1	50%	0.503	35%	0.346	S	S	.	.	T	Hydrogen-bonded Turn	trans	-111.6	-31.6	-176	52.1	0	0	0	0	113.7	Y151	Y151-S154 PolarHBondContact O-N 3.35Å
155	F	65	Low	82.7	Confident	120 Å²	120	75.1 Å²	75.1	53%	0.526	36%	0.356	S	S	.	.			trans	-140.5	99.5	-175.1	-71.7	-78.9	0	0	0	112.8	Y147 Y151	Y147-F155 HydrophobicContact CD1-CB 3.97Å; Y147-F155 HydrophobicContact CD1-CG 4.44Å; Y147-F155 HydrophobicContact CG-CB 4.49Å; Y151-F155 PolarHBondContact O-N 3.19Å
156	K	72.1	Confident	83.1	Confident	178 Å²	178	75.1 Å²	75.1	77%	0.774	36%	0.357	S	S	*	.	P	Polyproline II helix	trans	-99.9	123.4	166	-166.3	174.1	-177.9	179.1	0	109.4	S158	K156-S158 PolarHBondContact O-N 3.29Å
157	V	79.9	Confident	83.6	Confident	16 Å²	16	79.3 Å²	79.3	10%	0.097	38%	0.38	C	S	.	.	P	Polyproline II helix	trans	-62.7	121.7	170.6	-179.7	0	0	0	0	107.7	T81 D144 K161 A162 M165	T81-V157 WeakPolarHBondContact CG2-O 3.48Å; D144-V157 HydrophobicContact CB-CG2 4.12Å; D144-V157 WeakPolarHBondContact OD1-CB 3.42Å; V157-K161 HydrophobicContact CG1-CB 3.92Å; V157-A162 HydrophobicContact CG1-CB 4.22Å; V157-M165 HydrophobicContact CG1-SD 4.24Å
158	S	86.4	Confident	84.1	Confident	51 Å²	51	77.6 Å²	77.6	36%	0.357	39%	0.385	S	S	.	.	P	Polyproline II helix	trans	-79.1	163	175.4	71.1	0	0	0	0	110.4	K156 E160 K161 A162	K156-S158 PolarHBondContact O-N 3.29Å; S158-E160 VanDerWaalsContact C-N 3.25Å; S158-E160 PolarHBondContact O-N 3.12Å; S158-K161 PolarHBondContact O-N 3.16Å; S158-K161 WeakPolarHBondContact OG-CG 3.44Å; S158-K161 PolarHBondContact OG-N 3.47Å; S158-A162 PolarHBondContact O-N 3.08Å
159	R	86.2	Confident	84.9	Confident	126 Å²	126	76.9 Å²	76.9	48%	0.475	38%	0.381	S	S	.	.	H	α-helix	trans	-57.3	-41.4	176	-64.7	177.8	178.7	161.9	-2.8	111.7	Q79 T81 Y84 A162 K163	Q79-R159 PolarHBondContact O-NH2 3.04Å; T81-R159 HydrophobicContact CG2-CG 4.38Å; Y84-R159 HydrophobicContact CE2-CB 4.16Å; Y84-R159 HydrophobicContact CE2-CG 4.08Å; R159-A162 PolarHBondContact O-N 3.34Å; R159-K163 WeakPolarHBondContact O-CG 3.43Å; R159-K163 PolarHBondContact O-N 3.3Å
160	E	89.1	Confident	85.7	Confident	103 Å²	103	79.8 Å²	79.8	48%	0.481	39%	0.392	S	S	.	.	H	α-helix	trans	-66.6	-38.8	177.6	-62	-49.6	126.8	0	0	112.5	S158 K163 K164	S158-E160 VanDerWaalsContact C-N 3.25Å; S158-E160 PolarHBondContact O-N 3.12Å; E160-K163 PolarHBondContact O-N 2.75Å; E160-K163 IonicContact OE1-NZ 3.72Å; E160-K163 PolarHBondContact OE1-NZ 3.24Å; E160-K163 IonicContact OE2-NZ 3.33Å; E160-K164 WeakPolarHBondContact O-CG 3.22Å; E160-K164 PolarHBondContact O-N 2.76Å
161	K	90.9	Very high	86.4	Confident	115 Å²	115	84 Å²	84	50%	0.5	41%	0.413	S	S	.	.	H	α-helix	trans	-62.6	-43.3	172.7	-74.2	179.1	-179.3	-178.1	0	111.3	V157 S158 K163 K164 M165	V157-K161 HydrophobicContact CG1-CB 3.92Å; S158-K161 PolarHBondContact O-N 3.16Å; S158-K161 WeakPolarHBondContact OG-CG 3.44Å; S158-K161 PolarHBondContact OG-N 3.47Å; K161-K163 PolarHBondContact O-N 3.01Å; K161-K164 PolarHBondContact O-N 3.32Å; K161-M165 VanDerWaalsContact O-CG 3.27Å; K161-M165 WeakPolarHBondContact O-CG 3.46Å; K161-M165 PolarHBondContact O-N 3.49Å
162	A	91.6	Very high	87.1	Confident	0 Å²	0	84 Å²	84	0%	0	42%	0.415	C	S	.	.	H	α-helix	trans	-61.3	-44.5	177.2	0	0	0	0	0	112.3	T81 F85 V157 S158 R159 K164 M165 I166	T81-A162 HydrophobicContact CG2-CB 4.29Å; F85-A162 HydrophobicContact CE2-CB 3.98Å; F85-A162 HydrophobicContact CZ-CB 3.81Å; V157-A162 HydrophobicContact CG1-CB 4.22Å; S158-A162 PolarHBondContact O-N 3.08Å; R159-A162 PolarHBondContact O-N 3.34Å; A162-K164 VanDerWaalsContact C-N 3.34Å; A162-K164 PolarHBondContact O-N 3.23Å; A162-M165 PolarHBondContact O-N 2.86Å; A162-I166 WeakPolarHBondContact O-CG1 3.35Å; A162-I166 PolarHBondContact O-N 3Å
163	K	92.8	Very high	88.5	Confident	82 Å²	82	80.9 Å²	80.9	36%	0.357	40%	0.396	S	S	.	.	H	α-helix	trans	-60.1	-42.7	174.4	-68.9	173.4	-173.6	167.6	0	112.2	Y84 R159 E160 K161 I166 L167	Y84-K163 HydrophobicContact CD1-CG 4.36Å; R159-K163 WeakPolarHBondContact O-CG 3.43Å; R159-K163 PolarHBondContact O-N 3.3Å; E160-K163 PolarHBondContact O-N 2.75Å; E160-K163 IonicContact OE1-NZ 3.72Å; E160-K163 PolarHBondContact OE1-NZ 3.24Å; E160-K163 IonicContact OE2-NZ 3.33Å; K161-K163 PolarHBondContact O-N 3.01Å; K163-I166 PolarHBondContact O-N 3.12Å; K163-L167 WeakPolarHBondContact O-CB 3.46Å; K163-L167 PolarHBondContact O-N 3.22Å
164	K	95.4	Very high	89.9	Confident	149 Å²	149	73.8 Å²	73.8	65%	0.648	36%	0.362	S	S	*	.	H	α-helix	trans	-64.1	-40.5	175.9	-72.4	179.6	-178.3	-171.1	0	112.2	E160 K161 A162 I166 L167 A168	E160-K164 WeakPolarHBondContact O-CG 3.22Å; E160-K164 PolarHBondContact O-N 2.76Å; K161-K164 PolarHBondContact O-N 3.32Å; A162-K164 VanDerWaalsContact C-N 3.34Å; A162-K164 PolarHBondContact O-N 3.23Å; K164-I166 VanDerWaalsContact C-N 3.35Å; K164-L167 PolarHBondContact O-N 3.37Å; K164-A168 VanDerWaalsContact O-CB 3.26Å; K164-A168 WeakPolarHBondContact O-CB 3.37Å; K164-A168 PolarHBondContact O-N 3.21Å
165	M	95.7	Very high	91.5	Very high	42 Å²	42	73.7 Å²	73.7	21%	0.207	37%	0.365	C	S	.	.	H	α-helix	trans	-62.3	-41.7	174.7	-70.3	169.2	67.7	0	0	111.7	F85 S140 V143 V157 K161 A162 S169	F85-M165 HydrophobicContact CE1-CB 4.2Å; F85-M165 HydrophobicContact CZ-CB 4.43Å; F85-M165 HydrophobicContact CZ-CE 4.24Å; F85-M165 HydrophobicContact CZ-SD 4.33Å; S140-M165 VanDerWaalsContact O-CE 3.25Å; S140-M165 WeakPolarHBondContact O-CE 3.22Å; V143-M165 HydrophobicContact CB-CE 4.18Å; V143-M165 HydrophobicContact CG1-CE 4.15Å; V157-M165 HydrophobicContact CG1-SD 4.24Å; K161-M165 VanDerWaalsContact O-CG 3.27Å; K161-M165 WeakPolarHBondContact O-CG 3.46Å; K161-M165 PolarHBondContact O-N 3.49Å; A162-M165 PolarHBondContact O-N 2.86Å; M165-S169 WeakPolarHBondContact O-CB 3.38Å; M165-S169 PolarHBondContact O-N 3.03Å; M165-S169 PolarHBondContact O-OG 3.41Å
166	I	97	Very high	93	Very high	22 Å²	22	69 Å²	69	11%	0.113	35%	0.345	C	S	.	.	H	α-helix	trans	-61.4	-54.9	173.7	-68.7	163.1	0	0	0	109.9	Y84 F85 S88 A162 K163 K164 A168 S169 W170	Y84-I166 WeakPolarHBondContact O-CD1 3.39Å; F85-I166 HydrophobicContact CD1-CD1 3.78Å; F85-I166 HydrophobicContact CD1-CG1 3.46Å; F85-I166 VanDerWaalsContact CD1-CG1 3.46Å; F85-I166 HydrophobicContact CE1-CD1 4.17Å; F85-I166 HydrophobicContact CE1-CG1 3.67Å; F85-I166 HydrophobicContact CG-CD1 4.39Å; F85-I166 HydrophobicContact CG-CG1 4.49Å; S88-I166 WeakPolarHBondContact OG-CG2 3.5Å; A162-I166 WeakPolarHBondContact O-CG1 3.35Å; A162-I166 PolarHBondContact O-N 3Å; K163-I166 PolarHBondContact O-N 3.12Å; K164-I166 VanDerWaalsContact C-N 3.35Å; I166-A168 VanDerWaalsContact C-N 3.27Å; I166-A168 PolarHBondContact O-N 3Å; I166-S169 WeakPolarHBondContact O-CA 3.42Å; I166-S169 WeakPolarHBondContact O-CB 3.31Å; I166-S169 PolarHBondContact O-N 2.67Å; I166-W170 VanDerWaalsContact O-CD1 3.28Å; I166-W170 PolarHBondContact O-N 3.12Å
167	L	97.5	Very high	94.1	Very high	102 Å²	102	60.9 Å²	60.9	53%	0.534	31%	0.31	S	S	.	.	H	α-helix	trans	-55.5	-44	180	-180	62.6	0	0	0	111.7	K163 K164 S169 W170 L171	K163-L167 WeakPolarHBondContact O-CB 3.46Å; K163-L167 PolarHBondContact O-N 3.22Å; K164-L167 PolarHBondContact O-N 3.37Å; L167-S169 VanDerWaalsContact C-N 3.34Å; L167-S169 PolarHBondContact O-N 3.33Å; L167-W170 PolarHBondContact O-N 3.05Å; L167-L171 HydrophobicContact CD1-CD1 3.96Å; L167-L171 HydrophobicContact CD1-CG 4.06Å; L167-L171 HydrophobicContact CG-CD1 3.91Å; L167-L171 HydrophobicContact CG-CG 4.37Å; L167-L171 WeakPolarHBondContact O-CB 3.44Å; L167-L171 WeakPolarHBondContact O-CG 3.35Å; L167-L171 PolarHBondContact O-N 3.06Å
168	A	97.7	Very high	94.8	Very high	57 Å²	57	61.9 Å²	61.9	47%	0.471	32%	0.32	S	S	.	.	H	α-helix	trans	-61.4	-40.8	175.5	0	0	0	0	0	112.1	K164 I166 W170 F172	K164-A168 VanDerWaalsContact O-CB 3.26Å; K164-A168 WeakPolarHBondContact O-CB 3.37Å; K164-A168 PolarHBondContact O-N 3.21Å; I166-A168 VanDerWaalsContact C-N 3.27Å; I166-A168 PolarHBondContact O-N 3Å; A168-W170 PolarHBondContact O-N 3.41Å; A168-F172 WeakPolarHBondContact O-CB 3.22Å; A168-F172 PolarHBondContact O-N 3.16Å
169	S	97.8	Very high	95.1	Very high	9 Å²	9	61.9 Å²	61.9	6%	0.063	32%	0.319	C	S	.	.	H	α-helix	trans	-61.6	-43.6	176.4	-57.2	0	0	0	0	111.7	Y136 S140 M165 I166 L167 D173	Y136-S169 PolarHBondContact O-OG 3.03Å; S140-S169 PolarHBondContact OG-OG 3.46Å; M165-S169 WeakPolarHBondContact O-CB 3.38Å; M165-S169 PolarHBondContact O-N 3.03Å; M165-S169 PolarHBondContact O-OG 3.41Å; I166-S169 WeakPolarHBondContact O-CA 3.42Å; I166-S169 WeakPolarHBondContact O-CB 3.31Å; I166-S169 PolarHBondContact O-N 2.67Å; L167-S169 VanDerWaalsContact C-N 3.34Å; L167-S169 PolarHBondContact O-N 3.33Å; S169-D173 VanDerWaalsContact O-CB 3.32Å; S169-D173 WeakPolarHBondContact O-CB 3.4Å; S169-D173 PolarHBondContact O-N 3.31Å; S169-D173 VanDerWaalsContact O-N 3.1Å
170	W	98.3	Very high	95.3	Very high	64 Å²	64	55.9 Å²	55.9	24%	0.242	30%	0.296	C	S	.	.	H	α-helix	trans	-66.8	-48.4	177.7	-80.6	83.4	0	0	0	112.6	S88 A92 L95 V133 I166 L167 A168 A174	S88-W170 PolarHBondContact OG-NE1 3.04Å; A92-W170 HydrophobicContact CB-CH2 4.32Å; A92-W170 HydrophobicContact CB-CZ2 4.22Å; L95-W170 HydrophobicContact CD2-CH2 4.19Å; L95-W170 HydrophobicContact CD2-CZ3 4.06Å; V133-W170 HydrophobicContact CG1-CD2 3.69Å; V133-W170 VanDerWaalsContact CG1-CE2 3.44Å; V133-W170 HydrophobicContact CG1-CE3 4.24Å; V133-W170 HydrophobicContact CG1-CG 4.02Å; V133-W170 HydrophobicContact CG1-CH2 4.35Å; V133-W170 HydrophobicContact CG1-CZ2 3.81Å; V133-W170 HydrophobicContact CG2-CD2 4.02Å; V133-W170 HydrophobicContact CG2-CE3 3.91Å; V133-W170 HydrophobicContact CG2-CG 4.37Å; V133-W170 HydrophobicContact CG2-CZ3 4.37Å; I166-W170 VanDerWaalsContact O-CD1 3.28Å; I166-W170 PolarHBondContact O-N 3.12Å; L167-W170 PolarHBondContact O-N 3.05Å; A168-W170 PolarHBondContact O-N 3.41Å; W170-A174 WeakPolarHBondContact O-CB 3.17Å; W170-A174 PolarHBondContact O-N 3.44Å
171	L	98.2	Very high	95.3	Very high	109 Å²	109	54.6 Å²	54.6	57%	0.571	29%	0.289	S	S	*	.	H	α-helix	trans	-67.8	-40.8	-178.2	-68.2	177.5	0	0	0	111.9	L167 A175	L167-L171 HydrophobicContact CD1-CD1 3.96Å; L167-L171 HydrophobicContact CD1-CG 4.06Å; L167-L171 HydrophobicContact CG-CD1 3.91Å; L167-L171 HydrophobicContact CG-CG 4.37Å; L167-L171 WeakPolarHBondContact O-CB 3.44Å; L167-L171 WeakPolarHBondContact O-CG 3.35Å; L167-L171 PolarHBondContact O-N 3.06Å; L171-A175 WeakPolarHBondContact O-CB 3.2Å; L171-A175 PolarHBondContact O-N 3.14Å
172	F	97.3	Very high	95.2	Very high	105 Å²	105	58 Å²	58	46%	0.461	30%	0.304	S	S	.	.	H	α-helix	trans	-61.5	-50.9	177	178.9	-93.5	0	0	0	110.8	Y136 A168 A175 F176	Y136-F172 HydrophobicContact CD1-CD1 4.26Å; Y136-F172 HydrophobicContact CD1-CE1 4.45Å; Y136-F172 HydrophobicContact CD2-CD1 4.28Å; Y136-F172 AromaticContact CE1-CD1 3.91Å; Y136-F172 HydrophobicContact CE1-CD1 3.91Å; Y136-F172 AromaticContact CE1-CE1 3.66Å; Y136-F172 HydrophobicContact CE1-CE1 3.66Å; Y136-F172 AromaticContact CE2-CD1 3.94Å; Y136-F172 HydrophobicContact CE2-CD1 3.94Å; Y136-F172 AromaticContact CE2-CE1 3.98Å; Y136-F172 HydrophobicContact CE2-CE1 3.98Å; Y136-F172 HydrophobicContact CG-CD1 4.45Å; Y136-F172 AromaticContact CZ-CD1 3.76Å; Y136-F172 AromaticContact CZ-CE1 3.41Å; Y136-F172 VanDerWaalsContact CZ-CE1 3.41Å; Y136-F172 WeakPolarHBondContact OH-CE1 3.47Å; A168-F172 WeakPolarHBondContact O-CB 3.22Å; A168-F172 PolarHBondContact O-N 3.16Å; F172-A175 PolarHBondContact O-N 3.01Å; F172-F176 VanDerWaalsContact O-CB 3.24Å; F172-F176 WeakPolarHBondContact O-CB 3.08Å; F172-F176 PolarHBondContact O-N 3.02Å
173	D	97.9	Very high	94.9	Very high	1 Å²	1	60.6 Å²	60.6	1%	0.005	32%	0.316	C	S	.	.	H	α-helix	trans	-67.4	-38.8	-179.4	-165.9	62.8	0	0	0	112.1	L129 G132 V133 Y136 S169 A175 F176 I177	L129-D173 WeakPolarHBondContact CA-OD2 3.32Å; L129-D173 HydrophobicContact CD1-CB 4.48Å; G132-D173 VanDerWaalsContact C-CG 3.41Å; G132-D173 VanDerWaalsContact C-OD2 3.25Å; G132-D173 WeakPolarHBondContact CA-OD1 3.14Å; G132-D173 VanDerWaalsContact CA-OD2 3.31Å; G132-D173 WeakPolarHBondContact CA-OD2 3.48Å; V133-D173 HydrophobicContact CG2-CB 3.93Å; V133-D173 PolarHBondContact N-OD2 2.82Å; Y136-D173 HydrophobicContact CD2-CB 3.85Å; Y136-D173 HydrophobicContact CE2-CB 4.14Å; Y136-D173 VanDerWaalsContact CE2-OD1 3.29Å; Y136-D173 WeakPolarHBondContact CE2-OD1 3.29Å; S169-D173 VanDerWaalsContact O-CB 3.32Å; S169-D173 WeakPolarHBondContact O-CB 3.4Å; S169-D173 PolarHBondContact O-N 3.31Å; S169-D173 VanDerWaalsContact O-N 3.1Å; D173-A175 VanDerWaalsContact C-N 3.34Å; D173-A175 PolarHBondContact O-N 3.5Å; D173-F176 WeakPolarHBondContact O-CB 3.27Å; D173-F176 PolarHBondContact O-N 3.03Å; D173-F176 VanDerWaalsContact O-N 3.14Å; D173-I177 WeakPolarHBondContact O-CB 3.35Å; D173-I177 VanDerWaalsContact O-CG1 3.28Å; D173-I177 WeakPolarHBondContact O-CG1 3.41Å; D173-I177 PolarHBondContact O-N 3.09Å
174	A	97.5	Very high	94.6	Very high	27 Å²	27	57.1 Å²	57.1	22%	0.223	30%	0.3	C	S	.	.	H	α-helix	trans	-58.4	-44.7	173.9	0	0	0	0	0	112.6	Y125 L129 W170 A178	Y125-A174 VanDerWaalsContact OH-CA 3.26Å; Y125-A174 WeakPolarHBondContact OH-CA 3.47Å; Y125-A174 WeakPolarHBondContact OH-CB 3.43Å; Y125-A174 PolarHBondContact OH-O 3.08Å; Y125-A174 VanDerWaalsContact OH-O 3.1Å; L129-A174 HydrophobicContact CD1-CB 3.9Å; W170-A174 WeakPolarHBondContact O-CB 3.17Å; W170-A174 PolarHBondContact O-N 3.44Å; A174-A178 PolarHBondContact O-N 3.19Å; A174-A178 VanDerWaalsContact O-N 3.12Å
175	A	96.8	Very high	93.6	Very high	69 Å²	69	50.4 Å²	50.4	57%	0.57	27%	0.273	S	S	*	.	H	α-helix	trans	-66.6	-39.8	175.1	0	0	0	0	0	111.7	L171 F172 D173 A178	L171-A175 WeakPolarHBondContact O-CB 3.2Å; L171-A175 PolarHBondContact O-N 3.14Å; F172-A175 PolarHBondContact O-N 3.01Å; D173-A175 VanDerWaalsContact C-N 3.34Å; D173-A175 PolarHBondContact O-N 3.5Å; A175-A178 WeakPolarHBondContact O-CB 3.37Å; A175-A178 PolarHBondContact O-N 3.03Å
176	F	96	Very high	92.3	Very high	23 Å²	23	52 Å²	52	10%	0.101	29%	0.289	C	S	.	.	H	α-helix	trans	-63.9	-40.7	179.9	-177.8	-102.7	0	0	0	112.5	F172 D173 P179 F207 H208 V211	F172-F176 VanDerWaalsContact O-CB 3.24Å; F172-F176 WeakPolarHBondContact O-CB 3.08Å; F172-F176 PolarHBondContact O-N 3.02Å; D173-F176 WeakPolarHBondContact O-CB 3.27Å; D173-F176 PolarHBondContact O-N 3.03Å; D173-F176 VanDerWaalsContact O-N 3.14Å; F176-P179 VanDerWaalsContact O-CD 3.25Å; F176-P179 WeakPolarHBondContact O-CD 3.48Å; F176-F207 AromaticContact CD2-CE1 3.79Å; F176-F207 HydrophobicContact CD2-CE1 3.79Å; F176-F207 HydrophobicContact CD2-CZ 4.37Å; F176-F207 AromaticContact CE2-CD1 3.7Å; F176-F207 HydrophobicContact CE2-CD1 3.7Å; F176-F207 AromaticContact CE2-CE1 3.06Å; F176-F207 HydrophobicContact CE2-CE1 3.06Å; F176-F207 AromaticContact CE2-CZ 3.61Å; F176-F207 HydrophobicContact CE2-CZ 3.61Å; F176-F207 AromaticContact CZ-CD1 3.8Å; F176-F207 HydrophobicContact CZ-CD1 3.8Å; F176-F207 AromaticContact CZ-CE1 3.67Å; F176-F207 HydrophobicContact CZ-CE1 3.67Å; F176-F207 HydrophobicContact CZ-CZ 4.43Å; F176-H208 AromaticContact CE1-CD2 3.3Å; F176-H208 WeakPolarHBondContact CE1-CD2 3.5Å; F176-H208 AromaticContact CE1-NE2 3.79Å; F176-H208 AromaticContact CZ-CD2 3.73Å; F176-V211 HydrophobicContact CE2-CB 4Å; F176-V211 HydrophobicContact CE2-CG1 3.72Å; F176-V211 HydrophobicContact CZ-CB 3.95Å; F176-V211 HydrophobicContact CZ-CG1 4.08Å
177	I	96.1	Very high	90.4	Very high	6 Å²	6	56 Å²	56	3%	0.031	33%	0.326	C	S	.	.	H	α-helix	trans	-84	-13.4	-179.9	-58.9	-53.2	0	0	0	112.5	Y125 H128 D173 P179 C180 Y204 H208	Y125-I177 HydrophobicContact CD2-CB 4.41Å; Y125-I177 HydrophobicContact CD2-CG2 3.67Å; Y125-I177 HydrophobicContact CE2-CB 4Å; Y125-I177 HydrophobicContact CE2-CG2 3.77Å; H128-I177 HydrophobicContact CB-CD1 4.05Å; H128-I177 HydrophobicContact CB-CG1 4.33Å; H128-I177 HydrophobicContact CB-CG2 3.51Å; D173-I177 WeakPolarHBondContact O-CB 3.35Å; D173-I177 VanDerWaalsContact O-CG1 3.28Å; D173-I177 WeakPolarHBondContact O-CG1 3.41Å; D173-I177 PolarHBondContact O-N 3.09Å; I177-P179 VanDerWaalsContact C-N 3.29Å; I177-P179 VanDerWaalsContact O-N 3.11Å; I177-C180 HydrophobicContact CG2-CB 4.19Å; I177-C180 WeakPolarHBondContact O-CB 3.43Å; I177-C180 PolarHBondContact O-N 3.07Å; I177-Y204 PolarHBondContact O-OH 2.98Å; I177-H208 VanDerWaalsContact CD1-CE1 3.46Å; I177-H208 WeakPolarHBondContact CD1-CE1 3.02Å; I177-H208 VanDerWaalsContact CD1-NE2 3.29Å; I177-H208 WeakPolarHBondContact CD1-NE2 3.07Å
178	A	94.6	Very high	88.5	Confident	38 Å²	38	56.7 Å²	56.7	31%	0.314	33%	0.33	S	S	.	.	T	Hydrogen-bonded Turn	trans	-50.3	-36.6	-178.2	0	0	0	0	0	115.4	A174 A175 C180 F181	A174-A178 PolarHBondContact O-N 3.19Å; A174-A178 VanDerWaalsContact O-N 3.12Å; A175-A178 WeakPolarHBondContact O-CB 3.37Å; A175-A178 PolarHBondContact O-N 3.03Å; A178-C180 PolarHBondContact O-N 3.02Å; A178-F181 WeakPolarHBondContact O-CD2 3.39Å; A178-F181 PolarHBondContact O-N 3.12Å
179	P	92.4	Very high	86.5	Confident	50 Å²	50	58 Å²	58	33%	0.325	34%	0.335	S	S	.	.	T	Hydrogen-bonded Turn	trans	-60.9	-15.7	177.7	-22	33.9	0	0	0	114.5	F176 I177 F181 F182 F183 Y204	F176-P179 VanDerWaalsContact O-CD 3.25Å; F176-P179 WeakPolarHBondContact O-CD 3.48Å; I177-P179 VanDerWaalsContact C-N 3.29Å; I177-P179 VanDerWaalsContact O-N 3.11Å; P179-F181 PolarHBondContact O-N 3.1Å; P179-F181 VanDerWaalsContact O-N 3.09Å; P179-F182 WeakPolarHBondContact O-CD2 3.34Å; P179-F182 PolarHBondContact O-N 2.88Å; P179-F183 WeakPolarHBondContact O-CD2 3.43Å; P179-Y204 HydrophobicContact CB-CD2 4.24Å; P179-Y204 HydrophobicContact CB-CE2 3.79Å; P179-Y204 HydrophobicContact CG-CE2 4.37Å
180	C	89.9	Confident	85.2	Confident	1 Å²	1	61.6 Å²	61.6	1%	0.007	35%	0.351	C	S	.	.	H	α-helix	trans	-48.6	-35.6	172	-163.1	0	0	0	0	112.7	Y125 I177 A178 F182 F183 Y184 Y204	Y125-C180 HydrophobicContact CD2-CB 4.37Å; I177-C180 HydrophobicContact CG2-CB 4.19Å; I177-C180 WeakPolarHBondContact O-CB 3.43Å; I177-C180 PolarHBondContact O-N 3.07Å; A178-C180 PolarHBondContact O-N 3.02Å; C180-F182 PolarHBondContact O-N 3.47Å; C180-F182 VanDerWaalsContact O-N 3.15Å; C180-F183 PolarHBondContact O-N 2.95Å; C180-F183 VanDerWaalsContact O-N 3.08Å; C180-Y184 WeakPolarHBondContact O-CD2 3.38Å; C180-Y184 PolarHBondContact O-N 2.95Å; C180-Y184 WeakPolarHBondContact SG-CD2 3.48Å; C180-Y184 WeakPolarHBondContact SG-CE2 3.35Å; C180-Y204 WeakPolarHBondContact CA-OH 3.36Å; C180-Y204 WeakPolarHBondContact CB-OH 3.3Å; C180-Y204 PolarHBondContact N-OH 2.86Å; C180-Y204 VanDerWaalsContact N-OH 3.07Å
181	F	90.3	Very high	84.6	Confident	75 Å²	75	58.8 Å²	58.8	33%	0.329	34%	0.341	S	S	.	.	H	α-helix	trans	-64.3	-18.1	-178.1	-68.8	-59.9	0	0	0	114.5	K121 Y125 A178 P179	K121-F181 HydrophobicContact CB-CD1 3.86Å; K121-F181 HydrophobicContact CB-CE1 4.19Å; K121-F181 WeakPolarHBondContact CE-O 3.16Å; K121-F181 HydrophobicContact CG-CD1 4.31Å; Y125-F181 HydrophobicContact CD1-CE2 4.39Å; Y125-F181 AromaticContact CD1-CZ 3.79Å; Y125-F181 HydrophobicContact CD1-CZ 3.79Å; Y125-F181 HydrophobicContact CD2-CD2 4.17Å; Y125-F181 HydrophobicContact CD2-CE1 4.24Å; Y125-F181 AromaticContact CD2-CE2 3.41Å; Y125-F181 HydrophobicContact CD2-CE2 3.41Å; Y125-F181 VanDerWaalsContact CD2-CE2 3.41Å; Y125-F181 AromaticContact CD2-CZ 3.46Å; Y125-F181 HydrophobicContact CD2-CZ 3.46Å; Y125-F181 VanDerWaalsContact CD2-CZ 3.46Å; Y125-F181 HydrophobicContact CE1-CZ 4.29Å; Y125-F181 AromaticContact CE2-CE2 3.66Å; Y125-F181 HydrophobicContact CE2-CE2 3.66Å; Y125-F181 HydrophobicContact CE2-CZ 4.03Å; Y125-F181 AromaticContact CG-CE1 3.96Å; Y125-F181 HydrophobicContact CG-CE1 3.96Å; Y125-F181 AromaticContact CG-CE2 3.83Å; Y125-F181 HydrophobicContact CG-CE2 3.83Å; Y125-F181 AromaticContact CG-CZ 3.33Å; Y125-F181 HydrophobicContact CG-CZ 3.33Å; A178-F181 WeakPolarHBondContact O-CD2 3.39Å; A178-F181 PolarHBondContact O-N 3.12Å; P179-F181 PolarHBondContact O-N 3.1Å; P179-F181 VanDerWaalsContact O-N 3.09Å
182	F	88.3	Confident	84	Confident	186 Å²	186	57 Å²	57	82%	0.816	33%	0.332	S	S	*	.	H	α-helix	trans	-85	-26.7	175	-63.7	-72.3	0	0	0	112.9	P179 C180	P179-F182 WeakPolarHBondContact O-CD2 3.34Å; P179-F182 PolarHBondContact O-N 2.88Å; C180-F182 PolarHBondContact O-N 3.47Å; C180-F182 VanDerWaalsContact O-N 3.15Å
183	F	85.9	Confident	83.4	Confident	56 Å²	56	52.5 Å²	52.5	25%	0.246	31%	0.312	C	S	.	.	H	α-helix	trans	-90	-22.4	-174.8	-66.7	-76	0	0	0	113.8	P179 C180 L195 Y204	P179-F183 WeakPolarHBondContact O-CD2 3.43Å; C180-F183 PolarHBondContact O-N 2.95Å; C180-F183 VanDerWaalsContact O-N 3.08Å; F183-L195 HydrophobicContact CB-CD2 4.32Å; F183-L195 HydrophobicContact CD1-CD2 4.23Å; F183-L195 HydrophobicContact CG-CD2 4.12Å; F183-Y204 HydrophobicContact CD2-CD1 4.07Å; F183-Y204 HydrophobicContact CD2-CD2 4.43Å; F183-Y204 HydrophobicContact CD2-CE1 4.17Å; F183-Y204 HydrophobicContact CD2-CG 4.13Å; F183-Y204 HydrophobicContact CE2-CD1 4.02Å; F183-Y204 AromaticContact CE2-CD2 3.82Å; F183-Y204 HydrophobicContact CE2-CD2 3.82Å; F183-Y204 HydrophobicContact CE2-CE1 4.44Å; F183-Y204 HydrophobicContact CE2-CE2 4.31Å; F183-Y204 AromaticContact CE2-CG 3.61Å; F183-Y204 HydrophobicContact CE2-CG 3.61Å; F183-Y204 HydrophobicContact CZ-CG 4.15Å
184	Y	85.7	Confident	82.8	Confident	8 Å²	8	53.1 Å²	53.1	3%	0.031	32%	0.315	C	S	.	.	S	Bend	trans	-115.1	144.9	-177.4	-66	-75.9	0	0	0	112.6	K121 R124 C180 D192 L195	K121-Y184 WeakPolarHBondContact CE-O 3.4Å; K121-Y184 WeakPolarHBondContact CG-O 3.26Å; R124-Y184 HydrophobicContact CB-CD1 4.13Å; R124-Y184 HydrophobicContact CB-CD2 3.62Å; R124-Y184 HydrophobicContact CB-CE1 4.41Å; R124-Y184 HydrophobicContact CB-CE2 3.92Å; R124-Y184 HydrophobicContact CB-CG 3.71Å; R124-Y184 HydrophobicContact CG-CD1 3.61Å; R124-Y184 HydrophobicContact CG-CD2 4.07Å; R124-Y184 HydrophobicContact CG-CE1 3.91Å; R124-Y184 HydrophobicContact CG-CE2 4.33Å; R124-Y184 HydrophobicContact CG-CG 3.67Å; C180-Y184 WeakPolarHBondContact O-CD2 3.38Å; C180-Y184 PolarHBondContact O-N 2.95Å; C180-Y184 WeakPolarHBondContact SG-CD2 3.48Å; C180-Y184 WeakPolarHBondContact SG-CE2 3.35Å; Y184-D192 WeakPolarHBondContact CE1-O 3.45Å; Y184-L195 HydrophobicContact CE2-CD1 4.47Å; Y184-L195 WeakPolarHBondContact OH-CD1 3.34Å
185	G	74.9	Confident	82.2	Confident	8 Å²	8	52 Å²	52	8%	0.082	31%	0.305	C	S	.	.			trans	76.2	50.5	171.8	0	0	0	0	0	114.8	K121	K121-G185 WeakPolarHBondContact CE-O 3.09Å
186	S	67.8	Low	81.6	Confident	75 Å²	75	50.9 Å²	50.9	52%	0.524	29%	0.292	S	S	.	.			trans	-72	169.4	168.2	65.1	0	0	0	0	111.7	D188 S189	S186-D188 PolarHBondContact O-N 2.81Å; S186-S189 PolarHBondContact O-N 2.74Å
187	A	57	Low	80.9	Confident	108 Å²	108	53.1 Å²	53.1	89%	0.893	31%	0.311	S	S	*	.	T	Hydrogen-bonded Turn	trans	-55.4	-22.6	-170.3	0	0	0	0	0	114.9	S189	A187-S189 VanDerWaalsContact C-N 3.31Å; A187-S189 PolarHBondContact O-N 3.37Å
188	D	59.2	Low	80.4	Confident	116 Å²	116	55.1 Å²	55.1	62%	0.62	33%	0.325	S	S	*	.	T	Hydrogen-bonded Turn	trans	-89.9	13.3	-179.4	-58	-39.1	0	0	0	113.7	S186 H190	S186-D188 PolarHBondContact O-N 2.81Å; D188-H190 PolarHBondContact O-N 2.98Å; D188-H190 PolarHBondContact O-ND1 2.85Å
189	S	56	Low	80.1	Confident	83 Å²	83	63.8 Å²	63.8	58%	0.58	35%	0.35	S	S	*	.			trans	60.9	13.1	173.9	58.6	0	0	0	0	117	S186 A187 C191	S186-S189 PolarHBondContact O-N 2.74Å; A187-S189 VanDerWaalsContact C-N 3.31Å; A187-S189 PolarHBondContact O-N 3.37Å; S189-C191 PolarHBondContact O-N 3.33Å
190	H	70.3	Confident	79.9	Confident	86 Å²	86	63.1 Å²	63.1	40%	0.398	35%	0.352	S	S	.	.			trans	-69.1	115	173	-66.5	85.1	0	0	0	110	D188	D188-H190 PolarHBondContact O-N 2.98Å; D188-H190 PolarHBondContact O-ND1 2.85Å
191	C	84.1	Confident	79.9	Confident	4 Å²	4	63.1 Å²	63.1	3%	0.027	35%	0.352	C	S	.	.			trans	-114.8	66.8	176.5	-168.3	0	0	0	0	110.1	Q107 W113 C120 R124 S189	Q107-C191 PolarHBondContact NE2-O 2.88Å; W113-C191 HydrophobicContact CB-CB 3.51Å; W113-C191 HydrophobicContact CD2-CB 3.64Å; W113-C191 VanDerWaalsContact CD2-SG 3.58Å; W113-C191 HydrophobicContact CE3-CB 4.13Å; W113-C191 HydrophobicContact CG-CB 3.33Å; C120-C191 HydrophobicContact CB-CB 3.72Å; C120-C191 WeakPolarHBondContact CB-SG 3.43Å; C120-C191 WeakPolarHBondContact SG-CA 3.14Å; C120-C191 WeakPolarHBondContact SG-CB 3.39Å; C120-C191 CovalentContact SG-SG 2.02Å; C120-C191 PolarHBondContact SG-SG 3.15Å; R124-C191 PolarHBondContact NH2-O 3.13Å; S189-C191 PolarHBondContact O-N 3.33Å
192	D	85.9	Confident	79.9	Confident	72 Å²	72	62.8 Å²	62.8	39%	0.385	35%	0.353	S	S	.	.			trans	-70.9	153.8	-171.1	-55.9	-48.5	0	0	0	113	R124 Y184 F194	R124-D192 PolarHBondContact NE-O 3.05Å; R124-D192 VanDerWaalsContact NH2-C 3.29Å; R124-D192 PolarHBondContact NH2-O 3.37Å; Y184-D192 WeakPolarHBondContact CE1-O 3.45Å; D192-F194 VanDerWaalsContact C-N 3.31Å
193	F	84.8	Confident	80	Confident	10 Å²	10	58.4 Å²	58.4	4%	0.044	34%	0.341	C	S	.	.	S	Bend	trans	-72.2	-28.2	178.8	-68.3	-66.9	0	0	0	112.9	V104 Q107 V108 Q277 L292 F295	V104-F193 HydrophobicContact CG1-CE1 4.21Å; Q107-F193 HydrophobicContact CB-CE1 4.42Å; Q107-F193 HydrophobicContact CB-CZ 4.15Å; Q107-F193 HydrophobicContact CG-CE1 4.12Å; Q107-F193 HydrophobicContact CG-CE2 4.29Å; Q107-F193 HydrophobicContact CG-CZ 3.6Å; Q107-F193 VanDerWaalsContact OE1-CE1 3.25Å; V108-F193 HydrophobicContact CG2-CE1 4.34Å; V108-F193 HydrophobicContact CG2-CZ 3.87Å; F193-Q277 PolarHBondContact O-NE2 3.48Å; F193-L292 HydrophobicContact CE2-CD1 3.89Å; F193-L292 HydrophobicContact CZ-CD1 4.22Å; F193-F295 HydrophobicContact CB-CD1 4.29Å; F193-F295 HydrophobicContact CB-CD2 3.69Å; F193-F295 HydrophobicContact CB-CE1 4.44Å; F193-F295 HydrophobicContact CB-CE2 3.85Å; F193-F295 HydrophobicContact CB-CG 3.93Å; F193-F295 HydrophobicContact CB-CZ 4.24Å; F193-F295 AromaticContact CD1-CD1 3.45Å; F193-F295 HydrophobicContact CD1-CD1 3.45Å; F193-F295 VanDerWaalsContact CD1-CD1 3.45Å; F193-F295 HydrophobicContact CD1-CD2 4.24Å; F193-F295 AromaticContact CD1-CE1 3.2Å; F193-F295 HydrophobicContact CD1-CE1 3.2Å; F193-F295 HydrophobicContact CD1-CE2 4.02Å; F193-F295 AromaticContact CD1-CG 3.98Å; F193-F295 HydrophobicContact CD1-CG 3.98Å; F193-F295 AromaticContact CD1-CZ 3.52Å; F193-F295 HydrophobicContact CD1-CZ 3.52Å; F193-F295 AromaticContact CE1-CD1 3.81Å; F193-F295 HydrophobicContact CE1-CD1 3.81Å; F193-F295 AromaticContact CE1-CE1 3.58Å; F193-F295 HydrophobicContact CE1-CE1 3.58Å; F193-F295 HydrophobicContact CE1-CZ 4.28Å; F193-F295 AromaticContact CG-CD1 3.87Å; F193-F295 HydrophobicContact CG-CD1 3.87Å; F193-F295 HydrophobicContact CG-CD2 4.19Å; F193-F295 HydrophobicContact CG-CE1 4.03Å; F193-F295 HydrophobicContact CG-CE2 4.32Å; F193-F295 AromaticContact CG-CG 3.96Å; F193-F295 HydrophobicContact CG-CG 3.96Å; F193-F295 HydrophobicContact CG-CZ 4.25Å; F193-F295 HydrophobicContact CZ-CD1 4.49Å
194	F	85.4	Confident	80.3	Confident	14 Å²	14	56.5 Å²	56.5	6%	0.061	33%	0.333	C	S	.	.	S	Bend	trans	-111.7	160.4	179.6	-58.4	-76.1	0	0	0	109.7	D192 A276 P281 F294 F295	D192-F194 VanDerWaalsContact C-N 3.31Å; F194-A276 WeakPolarHBondContact CD1-O 3.03Å; F194-A276 HydrophobicContact CE1-CB 4.16Å; F194-P281 HydrophobicContact CD2-CG 4.28Å; F194-F294 HydrophobicContact CZ-CD1 4.11Å; F194-F294 HydrophobicContact CZ-CE1 4.48Å; F194-F295 HydrophobicContact CE1-CD2 4.32Å; F194-F295 HydrophobicContact CE2-CB 4.4Å; F194-F295 HydrophobicContact CZ-CB 4.07Å; F194-F295 HydrophobicContact CZ-CD2 4.06Å
195	L	85.8	Confident	80.7	Confident	4 Å²	4	56.3 Å²	56.3	2%	0.021	33%	0.333	C	S	.	.			trans	-72	146.6	173.4	-86.1	89	0	0	0	111.3	F183 Y184 Y204 H280	F183-L195 HydrophobicContact CB-CD2 4.32Å; F183-L195 HydrophobicContact CD1-CD2 4.23Å; F183-L195 HydrophobicContact CG-CD2 4.12Å; Y184-L195 HydrophobicContact CE2-CD1 4.47Å; Y184-L195 WeakPolarHBondContact OH-CD1 3.34Å; L195-Y204 HydrophobicContact CD2-CD1 3.46Å; L195-Y204 VanDerWaalsContact CD2-CD1 3.46Å; L195-Y204 HydrophobicContact CD2-CE1 4.02Å; L195-Y204 HydrophobicContact CD2-CG 4.45Å; L195-H280 PolarHBondContact O-ND1 3.36Å
196	P	83	Confident	81.6	Confident	46 Å²	46	57.9 Å²	57.9	30%	0.299	34%	0.344	S	S	.	.			trans	-62.5	153.4	179	24.6	-31.5	0	0	0	111	S198 S201	P196-S198 VanDerWaalsContact C-N 3.26Å; P196-S198 PolarHBondContact O-N 3.42Å; P196-S201 WeakPolarHBondContact CG-OG 3.36Å; P196-S201 WeakPolarHBondContact O-CB 3.19Å; P196-S201 PolarHBondContact O-OG 2.85Å
197	S	81.7	Confident	82.9	Confident	70 Å²	70	59.2 Å²	59.2	49%	0.49	34%	0.341	S	S	.	.	S	Bend	trans	-72.4	74.9	-178.8	53	0	0	0	0	111.7
198	S	86.1	Confident	84.6	Confident	47 Å²	47	54.5 Å²	54.5	33%	0.329	30%	0.3	S	S	.	.	S	Bend	trans	-130.7	152.7	176.7	82.7	0	0	0	0	111.7	P196 G200 S201 I202	P196-S198 VanDerWaalsContact C-N 3.26Å; P196-S198 PolarHBondContact O-N 3.42Å; S198-G200 PolarHBondContact O-N 3.15Å; S198-S201 WeakPolarHBondContact O-CB 3.3Å; S198-S201 PolarHBondContact O-N 3.45Å; S198-S201 VanDerWaalsContact O-N 3.09Å; S198-S201 WeakPolarHBondContact OG-CB 3.45Å; S198-S201 PolarHBondContact OG-N 3.25Å; S198-S201 PolarHBondContact OG-OG 3.32Å; S198-I202 WeakPolarHBondContact O-CG1 3.38Å; S198-I202 PolarHBondContact O-N 3.13Å
199	W	87.3	Confident	86.3	Confident	221 Å²	221	50.3 Å²	50.3	84%	0.837	28%	0.278	S	S	*	.	H	α-helix	trans	-56.4	-36.9	173.6	-72.6	98	0	0	0	112.4	T203	W199-T203 WeakPolarHBondContact O-CB 3.32Å; W199-T203 PolarHBondContact O-N 2.82Å; W199-T203 PolarHBondContact O-OG1 2.79Å
200	G	89.6	Confident	88.2	Confident	36 Å²	36	51.1 Å²	51.1	37%	0.371	28%	0.275	S	S	.	.	H	α-helix	trans	-63.9	-43.9	175.3	0	0	0	0	0	112.2	S198 T203 Y204	S198-G200 PolarHBondContact O-N 3.15Å; G200-T203 PolarHBondContact O-N 2.95Å; G200-Y204 VanDerWaalsContact O-CB 3.28Å; G200-Y204 WeakPolarHBondContact O-CB 2.92Å; G200-Y204 PolarHBondContact O-N 3.07Å
201	S	88.4	Confident	89.3	Confident	0 Å²	0	49 Å²	49	0%	0	27%	0.268	C	S	.	.	H	α-helix	trans	-63.1	-46.7	177.3	-65.6	0	0	0	0	112.8	P196 S198 T203 Y204 A205	P196-S201 WeakPolarHBondContact CG-OG 3.36Å; P196-S201 WeakPolarHBondContact O-CB 3.19Å; P196-S201 PolarHBondContact O-OG 2.85Å; S198-S201 WeakPolarHBondContact O-CB 3.3Å; S198-S201 PolarHBondContact O-N 3.45Å; S198-S201 VanDerWaalsContact O-N 3.09Å; S198-S201 WeakPolarHBondContact OG-CB 3.45Å; S198-S201 PolarHBondContact OG-N 3.25Å; S198-S201 PolarHBondContact OG-OG 3.32Å; S201-T203 VanDerWaalsContact C-N 3.33Å; S201-T203 PolarHBondContact O-N 3.32Å; S201-Y204 PolarHBondContact O-N 3.21Å; S201-A205 WeakPolarHBondContact O-CB 3.42Å; S201-A205 PolarHBondContact O-N 2.93Å
202	I	90	Very high	89.7	Confident	69 Å²	69	49 Å²	49	35%	0.354	27%	0.269	S	S	.	.	H	α-helix	trans	-60.7	-46.8	177.7	-66.1	161	0	0	0	109.7	S198 Y204 A205 A206 H280	S198-I202 WeakPolarHBondContact O-CG1 3.38Å; S198-I202 PolarHBondContact O-N 3.13Å; I202-Y204 VanDerWaalsContact C-N 3.32Å; I202-Y204 PolarHBondContact O-N 3.49Å; I202-A205 PolarHBondContact O-N 3.48Å; I202-A206 VanDerWaalsContact O-CB 3.23Å; I202-A206 WeakPolarHBondContact O-CB 3.37Å; I202-A206 PolarHBondContact O-N 3.24Å; I202-H280 VanDerWaalsContact CG1-CD2 3.44Å; I202-H280 WeakPolarHBondContact CG1-CD2 3.23Å; I202-H280 WeakPolarHBondContact CG1-NE2 3.22Å
203	T	92.2	Very high	90.1	Very high	93 Å²	93	45.7 Å²	45.7	57%	0.571	25%	0.251	S	S	*	.	H	α-helix	trans	-60.5	-44.3	179	-57.9	0	0	0	0	110.9	W199 G200 S201 F207	W199-T203 WeakPolarHBondContact O-CB 3.32Å; W199-T203 PolarHBondContact O-N 2.82Å; W199-T203 PolarHBondContact O-OG1 2.79Å; G200-T203 PolarHBondContact O-N 2.95Å; S201-T203 VanDerWaalsContact C-N 3.33Å; S201-T203 PolarHBondContact O-N 3.32Å; T203-F207 VanDerWaalsContact O-CB 3.22Å; T203-F207 WeakPolarHBondContact O-CB 3.47Å; T203-F207 PolarHBondContact O-N 2.74Å
204	Y	92.1	Very high	90.6	Very high	17 Å²	17	49.4 Å²	49.4	7%	0.067	27%	0.271	C	S	.	.	H	α-helix	trans	-65.4	-46.7	178.1	176	-102.2	0	0	0	112.5	I177 P179 C180 F183 L195 G200 S201 I202 A206 F207 H208	I177-Y204 PolarHBondContact O-OH 2.98Å; P179-Y204 HydrophobicContact CB-CD2 4.24Å; P179-Y204 HydrophobicContact CB-CE2 3.79Å; P179-Y204 HydrophobicContact CG-CE2 4.37Å; C180-Y204 WeakPolarHBondContact CA-OH 3.36Å; C180-Y204 WeakPolarHBondContact CB-OH 3.3Å; C180-Y204 PolarHBondContact N-OH 2.86Å; C180-Y204 VanDerWaalsContact N-OH 3.07Å; F183-Y204 HydrophobicContact CD2-CD1 4.07Å; F183-Y204 HydrophobicContact CD2-CD2 4.43Å; F183-Y204 HydrophobicContact CD2-CE1 4.17Å; F183-Y204 HydrophobicContact CD2-CG 4.13Å; F183-Y204 HydrophobicContact CE2-CD1 4.02Å; F183-Y204 AromaticContact CE2-CD2 3.82Å; F183-Y204 HydrophobicContact CE2-CD2 3.82Å; F183-Y204 HydrophobicContact CE2-CE1 4.44Å; F183-Y204 HydrophobicContact CE2-CE2 4.31Å; F183-Y204 AromaticContact CE2-CG 3.61Å; F183-Y204 HydrophobicContact CE2-CG 3.61Å; F183-Y204 HydrophobicContact CZ-CG 4.15Å; L195-Y204 HydrophobicContact CD2-CD1 3.46Å; L195-Y204 VanDerWaalsContact CD2-CD1 3.46Å; L195-Y204 HydrophobicContact CD2-CE1 4.02Å; L195-Y204 HydrophobicContact CD2-CG 4.45Å; G200-Y204 VanDerWaalsContact O-CB 3.28Å; G200-Y204 WeakPolarHBondContact O-CB 2.92Å; G200-Y204 PolarHBondContact O-N 3.07Å; S201-Y204 PolarHBondContact O-N 3.21Å; I202-Y204 VanDerWaalsContact C-N 3.32Å; I202-Y204 PolarHBondContact O-N 3.49Å; Y204-A206 PolarHBondContact O-N 3.49Å; Y204-F207 PolarHBondContact O-N 2.6Å; Y204-H208 AromaticContact CE1-CE1 3.36Å; Y204-H208 WeakPolarHBondContact CE1-CE1 3.44Å; Y204-H208 AromaticContact CE1-ND1 3.53Å; Y204-H208 AromaticContact CE2-CE1 3.39Å; Y204-H208 WeakPolarHBondContact CE2-CE1 3.34Å; Y204-H208 AromaticContact CE2-NE2 3.35Å; Y204-H208 VanDerWaalsContact CE2-NE2 3.35Å; Y204-H208 WeakPolarHBondContact CE2-NE2 3.24Å; Y204-H208 AromaticContact CZ-CE1 2.92Å; Y204-H208 AromaticContact CZ-ND1 3.59Å; Y204-H208 AromaticContact CZ-NE2 3.42Å; Y204-H208 WeakPolarHBondContact O-CB 3.48Å; Y204-H208 PolarHBondContact O-N 3.04Å; Y204-H208 PolarHBondContact OH-CE1 3.43Å
205	A	92.8	Very high	91.1	Very high	4 Å²	4	52.2 Å²	52.2	3%	0.033	29%	0.289	C	S	.	.	H	α-helix	trans	-61.9	-43.1	176.4	0	0	0	0	0	111.9	S201 I202 H208 L209 Q277 L278	S201-A205 WeakPolarHBondContact O-CB 3.42Å; S201-A205 PolarHBondContact O-N 2.93Å; I202-A205 PolarHBondContact O-N 3.48Å; A205-H208 PolarHBondContact O-N 3.16Å; A205-L209 PolarHBondContact O-N 3.29Å; A205-Q277 HydrophobicContact CB-CB 4.47Å; A205-Q277 WeakPolarHBondContact CB-O 3.43Å; A205-L278 HydrophobicContact CB-CD2 4.27Å
206	A	93.9	Very high	91.6	Very high	40 Å²	40	52.1 Å²	52.1	33%	0.331	29%	0.289	S	S	.	.	H	α-helix	trans	-64	-41.5	175.5	0	0	0	0	0	112	I202 Y204 L209 L210 L278	I202-A206 VanDerWaalsContact O-CB 3.23Å; I202-A206 WeakPolarHBondContact O-CB 3.37Å; I202-A206 PolarHBondContact O-N 3.24Å; Y204-A206 PolarHBondContact O-N 3.49Å; A206-L209 PolarHBondContact O-N 3.2Å; A206-L210 VanDerWaalsContact O-CB 3.3Å; A206-L210 WeakPolarHBondContact O-CB 3.44Å; A206-L210 PolarHBondContact O-N 2.62Å; A206-L278 HydrophobicContact CB-CD2 4.19Å
207	F	94.4	Very high	92.1	Very high	104 Å²	104	51.1 Å²	51.1	46%	0.456	28%	0.282	S	S	.	.	H	α-helix	trans	-63.6	-41.8	176.3	-175.9	-110.3	0	0	0	111.9	F176 T203 Y204 L210 V211	F176-F207 AromaticContact CD2-CE1 3.79Å; F176-F207 HydrophobicContact CD2-CE1 3.79Å; F176-F207 HydrophobicContact CD2-CZ 4.37Å; F176-F207 AromaticContact CE2-CD1 3.7Å; F176-F207 HydrophobicContact CE2-CD1 3.7Å; F176-F207 AromaticContact CE2-CE1 3.06Å; F176-F207 HydrophobicContact CE2-CE1 3.06Å; F176-F207 AromaticContact CE2-CZ 3.61Å; F176-F207 HydrophobicContact CE2-CZ 3.61Å; F176-F207 AromaticContact CZ-CD1 3.8Å; F176-F207 HydrophobicContact CZ-CD1 3.8Å; F176-F207 AromaticContact CZ-CE1 3.67Å; F176-F207 HydrophobicContact CZ-CE1 3.67Å; F176-F207 HydrophobicContact CZ-CZ 4.43Å; T203-F207 VanDerWaalsContact O-CB 3.22Å; T203-F207 WeakPolarHBondContact O-CB 3.47Å; T203-F207 PolarHBondContact O-N 2.74Å; Y204-F207 PolarHBondContact O-N 2.6Å; F207-L210 PolarHBondContact O-N 3.27Å; F207-V211 HydrophobicContact CD2-CB 4.44Å; F207-V211 HydrophobicContact CD2-CG2 3.79Å; F207-V211 HydrophobicContact CE2-CB 4.23Å; F207-V211 HydrophobicContact CE2-CG2 3.6Å; F207-V211 HydrophobicContact CZ-CB 4.43Å; F207-V211 HydrophobicContact CZ-CG1 4.5Å; F207-V211 HydrophobicContact CZ-CG2 4.24Å; F207-V211 WeakPolarHBondContact O-CB 3.06Å; F207-V211 PolarHBondContact O-N 3.19Å
208	H	93.9	Very high	92.8	Very high	8 Å²	8	49.8 Å²	49.8	4%	0.037	28%	0.279	C	S	.	.	I	π-helix	trans	-62.3	-46	172.6	-80	-176.1	0	0	0	113.4	H128 F176 I177 Y204 A205 G212 F213	H128-H208 AromaticContact CD2-ND1 3.99Å; F176-H208 AromaticContact CE1-CD2 3.3Å; F176-H208 WeakPolarHBondContact CE1-CD2 3.5Å; F176-H208 AromaticContact CE1-NE2 3.79Å; F176-H208 AromaticContact CZ-CD2 3.73Å; I177-H208 VanDerWaalsContact CD1-CE1 3.46Å; I177-H208 WeakPolarHBondContact CD1-CE1 3.02Å; I177-H208 VanDerWaalsContact CD1-NE2 3.29Å; I177-H208 WeakPolarHBondContact CD1-NE2 3.07Å; Y204-H208 AromaticContact CE1-CE1 3.36Å; Y204-H208 WeakPolarHBondContact CE1-CE1 3.44Å; Y204-H208 AromaticContact CE1-ND1 3.53Å; Y204-H208 AromaticContact CE2-CE1 3.39Å; Y204-H208 WeakPolarHBondContact CE2-CE1 3.34Å; Y204-H208 AromaticContact CE2-NE2 3.35Å; Y204-H208 VanDerWaalsContact CE2-NE2 3.35Å; Y204-H208 WeakPolarHBondContact CE2-NE2 3.24Å; Y204-H208 AromaticContact CZ-CE1 2.92Å; Y204-H208 AromaticContact CZ-ND1 3.59Å; Y204-H208 AromaticContact CZ-NE2 3.42Å; Y204-H208 WeakPolarHBondContact O-CB 3.48Å; Y204-H208 PolarHBondContact O-N 3.04Å; Y204-H208 PolarHBondContact OH-CE1 3.43Å; A205-H208 PolarHBondContact O-N 3.16Å; H208-G212 CarbonylContact O-C 3.28Å; H208-G212 WeakPolarHBondContact O-CA 3.06Å; H208-G212 PolarHBondContact O-N 2.95Å; H208-F213 PolarHBondContact O-N 3.44Å
209	L	94.6	Very high	93.3	Very high	29 Å²	29	51.1 Å²	51.1	15%	0.152	28%	0.282	C	S	.	.	I	π-helix	trans	-62.1	-46.6	176.1	174.3	64.9	0	0	0	110.9	A205 A206 F213 L214 L278	A205-L209 PolarHBondContact O-N 3.29Å; A206-L209 PolarHBondContact O-N 3.2Å; L209-F213 HydrophobicContact CD1-CD1 4.16Å; L209-F213 WeakPolarHBondContact O-CB 3.41Å; L209-F213 PolarHBondContact O-N 3.13Å; L209-L214 HydrophobicContact CD1-CD1 4.32Å; L209-L214 HydrophobicContact CD1-CG 4.14Å; L209-L214 HydrophobicContact CG-CD1 4.05Å; L209-L214 HydrophobicContact CG-CG 4.28Å; L209-L214 WeakPolarHBondContact O-CG 3.4Å; L209-L214 PolarHBondContact O-N 3.34Å; L209-L278 HydrophobicContact CD2-CD1 3.52Å
210	L	95.3	Very high	93.7	Very high	99 Å²	99	40.8 Å²	40.8	52%	0.518	24%	0.243	S	C	.	.	I	π-helix	trans	-72.3	-57.2	-174.8	-176.4	63.3	0	0	0	111.9	A206 F207 L214 V215	A206-L210 VanDerWaalsContact O-CB 3.3Å; A206-L210 WeakPolarHBondContact O-CB 3.44Å; A206-L210 PolarHBondContact O-N 2.62Å; F207-L210 PolarHBondContact O-N 3.27Å; L210-L214 HydrophobicContact CD1-CD1 4.46Å; L210-L214 PolarHBondContact O-N 3.42Å; L210-V215 WeakPolarHBondContact O-CG2 3.37Å; L210-V215 PolarHBondContact O-N 2.89Å
211	V	94.4	Very high	93.9	Very high	42 Å²	42	43 Å²	43	26%	0.255	25%	0.246	S	C	.	.	I	π-helix	trans	-86.8	-39.6	-172	-178.4	0	0	0	0	111.5	Y136 F176 F207 P216	Y136-V211 PolarHBondContact OH-O 3Å; F176-V211 HydrophobicContact CE2-CB 4Å; F176-V211 HydrophobicContact CE2-CG1 3.72Å; F176-V211 HydrophobicContact CZ-CB 3.95Å; F176-V211 HydrophobicContact CZ-CG1 4.08Å; F207-V211 HydrophobicContact CD2-CB 4.44Å; F207-V211 HydrophobicContact CD2-CG2 3.79Å; F207-V211 HydrophobicContact CE2-CB 4.23Å; F207-V211 HydrophobicContact CE2-CG2 3.6Å; F207-V211 HydrophobicContact CZ-CB 4.43Å; F207-V211 HydrophobicContact CZ-CG1 4.5Å; F207-V211 HydrophobicContact CZ-CG2 4.24Å; F207-V211 WeakPolarHBondContact O-CB 3.06Å; F207-V211 PolarHBondContact O-N 3.19Å; V211-P216 WeakPolarHBondContact O-CD 3.41Å; V211-P216 WeakPolarHBondContact O-CG 3.33Å
212	G	92.1	Very high	94.2	Very high	3 Å²	3	45 Å²	45	3%	0.031	26%	0.259	C	S	.	.	I	π-helix	trans	-75.6	-24.8	-179.8	0	0	0	0	0	114.1	H208	H208-G212 CarbonylContact O-C 3.28Å; H208-G212 WeakPolarHBondContact O-CA 3.06Å; H208-G212 PolarHBondContact O-N 2.95Å
213	F	93.9	Very high	94.3	Very high	4 Å²	4	43.7 Å²	43.7	2%	0.018	25%	0.251	C	S	.	.	I	π-helix	trans	-126.1	-63.1	-173.6	-168.4	-104.4	0	0	0	113.8	V135 H208 L209 P216 V217 F267 W270 T271 Y274	V135-F213 HydrophobicContact CG2-CD2 4.38Å; H208-F213 PolarHBondContact O-N 3.44Å; L209-F213 HydrophobicContact CD1-CD1 4.16Å; L209-F213 WeakPolarHBondContact O-CB 3.41Å; L209-F213 PolarHBondContact O-N 3.13Å; F213-P216 WeakPolarHBondContact O-CD 2.95Å; F213-V217 HydrophobicContact CE1-CG2 4.47Å; F213-V217 WeakPolarHBondContact O-CB 3.03Å; F213-V217 WeakPolarHBondContact O-CG2 3.49Å; F213-V217 PolarHBondContact O-N 3.17Å; F213-F267 HydrophobicContact CD2-CD1 4.2Å; F213-F267 HydrophobicContact CD2-CE1 4.42Å; F213-F267 AromaticContact CE2-CD1 3.5Å; F213-F267 HydrophobicContact CE2-CD1 3.5Å; F213-F267 HydrophobicContact CE2-CE1 4.13Å; F213-F267 HydrophobicContact CZ-CB 4.2Å; F213-F267 AromaticContact CZ-CD1 3.71Å; F213-F267 HydrophobicContact CZ-CD1 3.71Å; F213-F267 HydrophobicContact CZ-CG 4.45Å; F213-W270 HydrophobicContact CE2-CB 4.11Å; F213-T271 WeakPolarHBondContact CE1-OG1 3.2Å; F213-T271 WeakPolarHBondContact CZ-OG1 3.39Å; F213-Y274 HydrophobicContact CB-CD1 4.15Å; F213-Y274 HydrophobicContact CB-CD2 4.2Å; F213-Y274 HydrophobicContact CB-CE1 4.15Å; F213-Y274 HydrophobicContact CB-CE2 4.23Å; F213-Y274 HydrophobicContact CB-CG 4.18Å; F213-Y274 HydrophobicContact CD1-CD2 4.27Å; F213-Y274 AromaticContact CD2-CD2 3.41Å; F213-Y274 HydrophobicContact CD2-CD2 3.41Å; F213-Y274 VanDerWaalsContact CD2-CD2 3.41Å; F213-Y274 AromaticContact CD2-CE2 3.18Å; F213-Y274 HydrophobicContact CD2-CE2 3.18Å; F213-Y274 HydrophobicContact CD2-CG 4.21Å; F213-Y274 AromaticContact CD2-CZ 3.81Å; F213-Y274 HydrophobicContact CE1-CD2 4.49Å; F213-Y274 AromaticContact CE2-CD2 3.64Å; F213-Y274 HydrophobicContact CE2-CD2 3.64Å; F213-Y274 AromaticContact CE2-CE2 3.57Å; F213-Y274 HydrophobicContact CE2-CE2 3.57Å; F213-Y274 AromaticContact CG-CD2 3.73Å; F213-Y274 HydrophobicContact CG-CD2 3.73Å; F213-Y274 AromaticContact CG-CE2 3.87Å; F213-Y274 HydrophobicContact CG-CE2 3.87Å; F213-Y274 HydrophobicContact CG-CG 4.09Å; F213-Y274 HydrophobicContact CZ-CD2 4.2Å
214	L	95.6	Very high	94.2	Very high	87 Å²	87	39.7 Å²	39.7	46%	0.455	23%	0.226	S	C	.	.	I	π-helix	trans	-67.1	-43.2	-170.8	-66.5	177.6	0	0	0	113.9	L209 L210 V217 G218	L209-L214 HydrophobicContact CD1-CD1 4.32Å; L209-L214 HydrophobicContact CD1-CG 4.14Å; L209-L214 HydrophobicContact CG-CD1 4.05Å; L209-L214 HydrophobicContact CG-CG 4.28Å; L209-L214 WeakPolarHBondContact O-CG 3.4Å; L209-L214 PolarHBondContact O-N 3.34Å; L210-L214 HydrophobicContact CD1-CD1 4.46Å; L210-L214 PolarHBondContact O-N 3.42Å; L214-V217 WeakPolarHBondContact O-CB 3.47Å; L214-V217 PolarHBondContact O-N 3.02Å; L214-G218 PolarHBondContact O-N 3.26Å
215	V	96.3	Very high	94.1	Very high	73 Å²	73	43.9 Å²	43.9	44%	0.442	25%	0.246	S	C	.	.	H	α-helix	trans	-61.8	-51.9	177.3	165.5	0	0	0	0	111.1	L210 V217 G218 L219	L210-V215 WeakPolarHBondContact O-CG2 3.37Å; L210-V215 PolarHBondContact O-N 2.89Å; V215-V217 VanDerWaalsContact C-N 3.33Å; V215-V217 PolarHBondContact O-N 3.5Å; V215-G218 PolarHBondContact O-N 3.36Å; V215-L219 HydrophobicContact CG1-CD1 4.22Å; V215-L219 WeakPolarHBondContact O-CG 3.19Å; V215-L219 PolarHBondContact O-N 3.43Å
216	P	95.6	Very high	94.1	Very high	3 Å²	3	50.3 Å²	50.3	2%	0.019	27%	0.269	C	S	.	.	H	α-helix	trans	-56.3	-41.7	173.5	-28.9	34.5	0	0	0	113.9	V135 Y136 V211 F213 G218 L219 I220	V135-P216 HydrophobicContact CG1-CB 3.22Å; V135-P216 HydrophobicContact CG1-CG 3.73Å; Y136-P216 HydrophobicContact CE1-CG 4.04Å; V211-P216 WeakPolarHBondContact O-CD 3.41Å; V211-P216 WeakPolarHBondContact O-CG 3.33Å; F213-P216 WeakPolarHBondContact O-CD 2.95Å; P216-G218 PolarHBondContact O-N 3.46Å; P216-L219 PolarHBondContact O-N 3.05Å; P216-I220 WeakPolarHBondContact O-CB 3.5Å; P216-I220 WeakPolarHBondContact O-CD1 3.39Å; P216-I220 VanDerWaalsContact O-CG1 3.25Å; P216-I220 WeakPolarHBondContact O-CG1 3.42Å; P216-I220 PolarHBondContact O-N 2.88Å
217	V	94.4	Very high	93.8	Very high	25 Å²	25	48.4 Å²	48.4	15%	0.152	25%	0.253	C	S	.	.	H	α-helix	trans	-56.8	-49.6	174.9	168.2	0	0	0	0	110.8	F213 L214 V215 L219 I220 I221 F267	F213-V217 HydrophobicContact CE1-CG2 4.47Å; F213-V217 WeakPolarHBondContact O-CB 3.03Å; F213-V217 WeakPolarHBondContact O-CG2 3.49Å; F213-V217 PolarHBondContact O-N 3.17Å; L214-V217 WeakPolarHBondContact O-CB 3.47Å; L214-V217 PolarHBondContact O-N 3.02Å; V215-V217 VanDerWaalsContact C-N 3.33Å; V215-V217 PolarHBondContact O-N 3.5Å; V217-L219 VanDerWaalsContact C-N 3.35Å; V217-L219 PolarHBondContact O-N 3.45Å; V217-I220 PolarHBondContact O-N 3.21Å; V217-I221 HydrophobicContact CG1-CD1 3.68Å; V217-I221 HydrophobicContact CG1-CG1 4.43Å; V217-I221 WeakPolarHBondContact O-CB 3.36Å; V217-I221 VanDerWaalsContact O-CG1 3.29Å; V217-I221 WeakPolarHBondContact O-CG1 3.48Å; V217-I221 PolarHBondContact O-N 3.04Å; V217-F267 HydrophobicContact CB-CE1 4.49Å; V217-F267 HydrophobicContact CG2-CD1 3.24Å; V217-F267 HydrophobicContact CG2-CD2 4.03Å; V217-F267 HydrophobicContact CG2-CE1 3.19Å; V217-F267 HydrophobicContact CG2-CE2 4.01Å; V217-F267 HydrophobicContact CG2-CG 3.7Å; V217-F267 HydrophobicContact CG2-CZ 3.62Å
218	G	96	Very high	93.4	Very high	41 Å²	41	46 Å²	46	42%	0.423	25%	0.247	S	C	.	.	H	α-helix	trans	-59.3	-44.3	178.1	0	0	0	0	0	112.4	L214 V215 P216 I221 S222	L214-G218 PolarHBondContact O-N 3.26Å; V215-G218 PolarHBondContact O-N 3.36Å; P216-G218 PolarHBondContact O-N 3.46Å; G218-I221 PolarHBondContact O-N 2.92Å; G218-S222 WeakPolarHBondContact O-CB 3.14Å; G218-S222 PolarHBondContact O-N 3.34Å
219	L	96.5	Very high	93.1	Very high	76 Å²	76	51.8 Å²	51.8	40%	0.398	27%	0.269	S	S	.	.	H	α-helix	trans	-62.3	-47.3	176.7	-68.6	176.4	0	0	0	111.7	L139 V215 P216 V217 I221 S222 F223	L139-L219 HydrophobicContact CD1-CB 3.73Å; L139-L219 HydrophobicContact CD1-CD1 4.41Å; L139-L219 HydrophobicContact CD2-CD1 4.3Å; V215-L219 HydrophobicContact CG1-CD1 4.22Å; V215-L219 WeakPolarHBondContact O-CG 3.19Å; V215-L219 PolarHBondContact O-N 3.43Å; P216-L219 PolarHBondContact O-N 3.05Å; V217-L219 VanDerWaalsContact C-N 3.35Å; V217-L219 PolarHBondContact O-N 3.45Å; L219-I221 PolarHBondContact O-N 3.06Å; L219-S222 WeakPolarHBondContact O-CB 3.38Å; L219-S222 PolarHBondContact O-N 2.73Å; L219-S222 VanDerWaalsContact O-N 3.16Å; L219-S222 PolarHBondContact O-OG 3.09Å; L219-F223 HydrophobicContact CB-CE2 4.48Å; L219-F223 WeakPolarHBondContact O-CD2 3.37Å; L219-F223 PolarHBondContact O-N 3.18Å
220	I	95.1	Very high	92.7	Very high	3 Å²	3	53.5 Å²	53.5	2%	0.015	27%	0.273	C	S	.	.	H	α-helix	trans	-58.5	-48.5	178.1	-74.6	164.1	0	0	0	110.9	L138 L139 P216 V217 S222 F223 Y224 F267	L138-I220 HydrophobicContact CB-CD1 4.09Å; L139-I220 HydrophobicContact CB-CD1 4.13Å; L139-I220 HydrophobicContact CB-CG1 4.07Å; L139-I220 HydrophobicContact CD1-CG1 3.89Å; P216-I220 WeakPolarHBondContact O-CB 3.5Å; P216-I220 WeakPolarHBondContact O-CD1 3.39Å; P216-I220 VanDerWaalsContact O-CG1 3.25Å; P216-I220 WeakPolarHBondContact O-CG1 3.42Å; P216-I220 PolarHBondContact O-N 2.88Å; V217-I220 PolarHBondContact O-N 3.21Å; I220-S222 VanDerWaalsContact C-N 3.29Å; I220-S222 PolarHBondContact O-N 3.07Å; I220-F223 PolarHBondContact O-N 2.84Å; I220-Y224 HydrophobicContact CG2-CD2 3.62Å; I220-Y224 HydrophobicContact CG2-CE2 3.62Å; I220-Y224 VanDerWaalsContact O-CD2 3.28Å; I220-Y224 WeakPolarHBondContact O-CD2 3.34Å; I220-Y224 PolarHBondContact O-N 2.85Å; I220-F267 HydrophobicContact CD1-CE2 3.97Å; I220-F267 HydrophobicContact CD1-CZ 3.57Å; I220-F267 HydrophobicContact CG2-CE2 4.49Å
221	I	93.5	Very high	92.1	Very high	84 Å²	84	50.6 Å²	50.6	43%	0.431	26%	0.258	S	S	.	.	H	α-helix	trans	-58.5	-45.4	177.1	-70.1	169.6	0	0	0	109.8	V217 G218 L219 F223 Y224 Q225	V217-I221 HydrophobicContact CG1-CD1 3.68Å; V217-I221 HydrophobicContact CG1-CG1 4.43Å; V217-I221 WeakPolarHBondContact O-CB 3.36Å; V217-I221 VanDerWaalsContact O-CG1 3.29Å; V217-I221 WeakPolarHBondContact O-CG1 3.48Å; V217-I221 PolarHBondContact O-N 3.04Å; G218-I221 PolarHBondContact O-N 2.92Å; L219-I221 PolarHBondContact O-N 3.06Å; I221-F223 PolarHBondContact O-N 3.22Å; I221-Y224 PolarHBondContact O-N 2.66Å; I221-Q225 HydrophobicContact CG2-CG 4.13Å; I221-Q225 WeakPolarHBondContact O-CB 3.43Å; I221-Q225 VanDerWaalsContact O-CG 3.23Å; I221-Q225 WeakPolarHBondContact O-CG 3.45Å; I221-Q225 PolarHBondContact O-N 3.41Å
222	S	94.8	Very high	91.6	Very high	41 Å²	41	57.9 Å²	57.9	29%	0.287	28%	0.281	S	S	.	.	H	α-helix	trans	-61.5	-42.2	-179.8	83.8	0	0	0	0	112.7	G218 L219 I220 R226	G218-S222 WeakPolarHBondContact O-CB 3.14Å; G218-S222 PolarHBondContact O-N 3.34Å; L219-S222 WeakPolarHBondContact O-CB 3.38Å; L219-S222 PolarHBondContact O-N 2.73Å; L219-S222 VanDerWaalsContact O-N 3.16Å; L219-S222 PolarHBondContact O-OG 3.09Å; I220-S222 VanDerWaalsContact C-N 3.29Å; I220-S222 PolarHBondContact O-N 3.07Å; S222-R226 WeakPolarHBondContact O-CG 3.4Å; S222-R226 PolarHBondContact O-N 3.35Å; S222-R226 VanDerWaalsContact O-N 3.07Å
223	F	93.3	Very high	91.2	Very high	41 Å²	41	65.6 Å²	65.6	18%	0.18	31%	0.309	C	S	.	.	H	α-helix	trans	-65.2	-47.1	177.1	-77	-60.8	0	0	0	111	L139 S142 V143 F146 L219 I220 I221 Q225 R226 V227	L139-F223 HydrophobicContact CD1-CD2 4.21Å; L139-F223 HydrophobicContact CD1-CE2 4.08Å; S142-F223 WeakPolarHBondContact OG-CD2 3.36Å; V143-F223 HydrophobicContact CG2-CD2 4.2Å; V143-F223 HydrophobicContact CG2-CE1 4.46Å; V143-F223 HydrophobicContact CG2-CE2 3.7Å; V143-F223 HydrophobicContact CG2-CZ 3.86Å; F146-F223 HydrophobicContact CB-CD1 3.95Å; F146-F223 HydrophobicContact CD1-CD1 4.14Å; F146-F223 HydrophobicContact CD1-CE1 4.22Å; F146-F223 HydrophobicContact CD2-CD1 4.18Å; F146-F223 AromaticContact CG-CD1 3.82Å; F146-F223 HydrophobicContact CG-CD1 3.82Å; F146-F223 HydrophobicContact CG-CE1 4.36Å; L219-F223 HydrophobicContact CB-CE2 4.48Å; L219-F223 WeakPolarHBondContact O-CD2 3.37Å; L219-F223 PolarHBondContact O-N 3.18Å; I220-F223 PolarHBondContact O-N 2.84Å; I221-F223 PolarHBondContact O-N 3.22Å; F223-Q225 PolarHBondContact O-N 3.15Å; F223-R226 PolarHBondContact O-N 3.08Å; F223-V227 WeakPolarHBondContact O-CG2 3.47Å; F223-V227 PolarHBondContact O-N 3.34Å
224	Y	90.3	Very high	90.4	Very high	10 Å²	10	67.5 Å²	67.5	4%	0.039	32%	0.319	C	S	.	.	H	α-helix	trans	-65.5	-38.5	178.3	-79	-59.4	0	0	0	112.7	I220 I221 R226 V227 V228 I256 F259 N263	I220-Y224 HydrophobicContact CG2-CD2 3.62Å; I220-Y224 HydrophobicContact CG2-CE2 3.62Å; I220-Y224 VanDerWaalsContact O-CD2 3.28Å; I220-Y224 WeakPolarHBondContact O-CD2 3.34Å; I220-Y224 PolarHBondContact O-N 2.85Å; I221-Y224 PolarHBondContact O-N 2.66Å; Y224-R226 VanDerWaalsContact C-N 3.32Å; Y224-R226 PolarHBondContact O-N 2.94Å; Y224-V227 PolarHBondContact O-N 3.36Å; Y224-V228 WeakPolarHBondContact O-CG2 3.27Å; Y224-V228 PolarHBondContact O-N 2.85Å; Y224-I256 HydrophobicContact CD1-CG2 4.3Å; Y224-I256 HydrophobicContact CE1-CG2 4.43Å; Y224-F259 HydrophobicContact CE1-CB 4.35Å; Y224-F259 WeakPolarHBondContact OH-CB 3.26Å; Y224-N263 WeakPolarHBondContact CE2-ND2 3.45Å
225	Q	90.3	Very high	89.3	Confident	105 Å²	105	65.8 Å²	65.8	49%	0.491	32%	0.323	S	S	.	.	H	α-helix	trans	-59.6	-42.1	173.4	-76.7	176.8	-5.2	0	0	111.7	I221 F223 R229	I221-Q225 HydrophobicContact CG2-CG 4.13Å; I221-Q225 WeakPolarHBondContact O-CB 3.43Å; I221-Q225 VanDerWaalsContact O-CG 3.23Å; I221-Q225 WeakPolarHBondContact O-CG 3.45Å; I221-Q225 PolarHBondContact O-N 3.41Å; F223-Q225 PolarHBondContact O-N 3.15Å; Q225-R229 WeakPolarHBondContact O-CB 3.33Å; Q225-R229 VanDerWaalsContact O-CG 3.29Å; Q225-R229 WeakPolarHBondContact O-CG 3.46Å; Q225-R229 PolarHBondContact O-N 3.15Å
226	R	91.1	Very high	88.1	Confident	138 Å²	138	65.7 Å²	65.7	52%	0.521	33%	0.33	S	S	.	.	H	α-helix	trans	-64.1	-42.6	174.7	-71.6	-179.7	179.1	-157.1	-0.9	111.8	F146 S222 F223 Y224 Y230	F146-R226 HydrophobicContact CD2-CB 4.11Å; F146-R226 HydrophobicContact CE2-CB 3.81Å; F146-R226 HydrophobicContact CE2-CG 4.5Å; S222-R226 WeakPolarHBondContact O-CG 3.4Å; S222-R226 PolarHBondContact O-N 3.35Å; S222-R226 VanDerWaalsContact O-N 3.07Å; F223-R226 PolarHBondContact O-N 3.08Å; Y224-R226 VanDerWaalsContact C-N 3.32Å; Y224-R226 PolarHBondContact O-N 2.94Å; R226-Y230 WeakPolarHBondContact O-CB 3.31Å; R226-Y230 PolarHBondContact O-N 2.91Å
227	V	88.4	Confident	86.8	Confident	0 Å²	0	71.3 Å²	71.3	0%	0	36%	0.36	C	S	.	.	H	α-helix	trans	-61.4	-48.4	176.5	170.2	0	0	0	0	111.6	F146 I149 V150 F223 Y224 Y230 I231 I256	F146-V227 HydrophobicContact CB-CG2 4.15Å; F146-V227 HydrophobicContact CD2-CG2 4.17Å; I149-V227 HydrophobicContact CB-CG1 4.47Å; I149-V227 HydrophobicContact CD1-CG1 3.74Å; I149-V227 HydrophobicContact CG2-CG1 4.18Å; V150-V227 HydrophobicContact CG2-CG2 4.3Å; F223-V227 WeakPolarHBondContact O-CG2 3.47Å; F223-V227 PolarHBondContact O-N 3.34Å; Y224-V227 PolarHBondContact O-N 3.36Å; V227-Y230 PolarHBondContact O-N 2.96Å; V227-I231 HydrophobicContact CG1-CD1 3.98Å; V227-I231 WeakPolarHBondContact O-CG1 3.25Å; V227-I231 PolarHBondContact O-N 3.42Å; V227-I231 VanDerWaalsContact O-N 3.08Å; V227-I256 HydrophobicContact CG1-CD1 3.87Å; V227-I256 HydrophobicContact CG1-CG1 4.42Å
228	V	86.6	Confident	84.9	Confident	54 Å²	54	71.3 Å²	71.3	33%	0.327	36%	0.364	S	S	.	.	H	α-helix	trans	-64	-46.5	-179.7	172.3	0	0	0	0	110.6	Y224 Y230 I231 W232	Y224-V228 WeakPolarHBondContact O-CG2 3.27Å; Y224-V228 PolarHBondContact O-N 2.85Å; V228-Y230 VanDerWaalsContact C-N 3.32Å; V228-Y230 PolarHBondContact O-N 2.88Å; V228-I231 PolarHBondContact O-N 2.91Å; V228-W232 HydrophobicContact CG1-CG 4.48Å; V228-W232 PolarHBondContact O-N 3.48Å
229	R	88	Confident	82.9	Confident	130 Å²	130	77.2 Å²	77.2	49%	0.491	38%	0.381	S	S	.	.	H	α-helix	trans	-58.7	-41.9	176.2	-76.6	-171.3	-68.5	172.8	-5.4	112.5	Q225 W232 R233	Q225-R229 WeakPolarHBondContact O-CB 3.33Å; Q225-R229 VanDerWaalsContact O-CG 3.29Å; Q225-R229 WeakPolarHBondContact O-CG 3.46Å; Q225-R229 PolarHBondContact O-N 3.15Å; R229-W232 PolarHBondContact O-N 3.33Å; R229-R233 WeakPolarHBondContact O-CG 3.32Å; R229-R233 PolarHBondContact O-N 2.91Å
230	Y	85.9	Confident	80.8	Confident	64 Å²	64	79.8 Å²	79.8	25%	0.251	40%	0.4	S	S	.	.	H	α-helix	trans	-61.1	-45.3	176.6	177.6	-97.4	0	0	0	111.9	I149 V150 R226 V227 V228 W232 R233 I234	I149-Y230 HydrophobicContact CG2-CD1 4.06Å; I149-Y230 HydrophobicContact CG2-CE1 4.31Å; I149-Y230 WeakPolarHBondContact O-CE1 3.23Å; V150-Y230 HydrophobicContact CB-CD2 4.48Å; V150-Y230 HydrophobicContact CB-CG 4.41Å; V150-Y230 HydrophobicContact CG1-CD2 3.94Å; V150-Y230 HydrophobicContact CG1-CE2 4.19Å; V150-Y230 HydrophobicContact CG1-CG 4.3Å; V150-Y230 HydrophobicContact CG2-CD1 4.24Å; V150-Y230 HydrophobicContact CG2-CD2 4.5Å; V150-Y230 HydrophobicContact CG2-CG 4.03Å; V150-Y230 PolarHBondContact O-OH 3.18Å; R226-Y230 WeakPolarHBondContact O-CB 3.31Å; R226-Y230 PolarHBondContact O-N 2.91Å; V227-Y230 PolarHBondContact O-N 2.96Å; V228-Y230 VanDerWaalsContact C-N 3.32Å; V228-Y230 PolarHBondContact O-N 2.88Å; Y230-W232 VanDerWaalsContact C-N 3.34Å; Y230-W232 PolarHBondContact O-N 3.37Å; Y230-R233 PolarHBondContact O-N 3.41Å; Y230-I234 HydrophobicContact CD1-CD1 3.85Å; Y230-I234 HydrophobicContact CD2-CD1 4.41Å; Y230-I234 HydrophobicContact CE1-CD1 3.24Å; Y230-I234 HydrophobicContact CE1-CG1 4.48Å; Y230-I234 HydrophobicContact CE2-CD1 3.89Å; Y230-I234 HydrophobicContact CG-CD1 4.4Å; Y230-I234 WeakPolarHBondContact O-CG1 3.4Å; Y230-I234 PolarHBondContact O-N 3.34Å; Y230-I234 VanDerWaalsContact O-N 3.15Å; Y230-I234 WeakPolarHBondContact OH-CD1 3.44Å
231	I	83.1	Confident	78.8	Confident	38 Å²	38	84.1 Å²	84.1	20%	0.195	43%	0.426	C	S	.	.	H	α-helix	trans	-62.8	-42.2	177.1	-67.6	167.5	0	0	0	111.2	I149 V227 V228 G235 I256	I149-I231 HydrophobicContact CG2-CD1 4.29Å; I149-I231 HydrophobicContact CG2-CG1 4.18Å; V227-I231 HydrophobicContact CG1-CD1 3.98Å; V227-I231 WeakPolarHBondContact O-CG1 3.25Å; V227-I231 PolarHBondContact O-N 3.42Å; V227-I231 VanDerWaalsContact O-N 3.08Å; V228-I231 PolarHBondContact O-N 2.91Å; I231-G235 PolarHBondContact O-N 3.32Å; I231-I256 HydrophobicContact CD1-CD1 3.42Å; I231-I256 VanDerWaalsContact CD1-CD1 3.42Å
232	W	83.5	Confident	76.6	Confident	196 Å²	196	90.3 Å²	90.3	74%	0.742	44%	0.444	S	S	*	.	H	α-helix	trans	-65.5	-42.3	179.9	-78.4	36.1	0	0	0	112.1	V228 R229 Y230 G235 A236	V228-W232 HydrophobicContact CG1-CG 4.48Å; V228-W232 PolarHBondContact O-N 3.48Å; R229-W232 PolarHBondContact O-N 3.33Å; Y230-W232 VanDerWaalsContact C-N 3.34Å; Y230-W232 PolarHBondContact O-N 3.37Å; W232-G235 PolarHBondContact O-N 2.86Å; W232-A236 PolarHBondContact O-N 3.26Å
233	R	82.8	Confident	74.3	Confident	164 Å²	164	100.1 Å²	100.1	62%	0.619	48%	0.475	S	S	*	.	H	α-helix	trans	-60.4	-49.7	176.1	-73.7	179.2	-176.1	178.2	-1.7	112	R229 Y230 G235 A236 D237	R229-R233 WeakPolarHBondContact O-CG 3.32Å; R229-R233 PolarHBondContact O-N 2.91Å; Y230-R233 PolarHBondContact O-N 3.41Å; R233-G235 PolarHBondContact O-N 3.5Å; R233-A236 PolarHBondContact O-N 3.36Å; R233-A236 VanDerWaalsContact O-N 3.07Å; R233-D237 VanDerWaalsContact O-CG 3.27Å; R233-D237 PolarHBondContact O-N 3.48Å
234	I	77	Confident	72	Confident	44 Å²	44	104.2 Å²	104.2	23%	0.226	50%	0.504	C	S	.	.	H	α-helix	trans	-59.9	-36.4	176.4	-69.2	175.6	0	0	0	111.9	Y230 G238 I247	Y230-I234 HydrophobicContact CD1-CD1 3.85Å; Y230-I234 HydrophobicContact CD2-CD1 4.41Å; Y230-I234 HydrophobicContact CE1-CD1 3.24Å; Y230-I234 HydrophobicContact CE1-CG1 4.48Å; Y230-I234 HydrophobicContact CE2-CD1 3.89Å; Y230-I234 HydrophobicContact CG-CD1 4.4Å; Y230-I234 WeakPolarHBondContact O-CG1 3.4Å; Y230-I234 PolarHBondContact O-N 3.34Å; Y230-I234 VanDerWaalsContact O-N 3.15Å; Y230-I234 WeakPolarHBondContact OH-CD1 3.44Å; I234-G238 PolarHBondContact O-N 2.96Å; I234-I247 HydrophobicContact CD1-CG2 4.28Å; I234-I247 HydrophobicContact CG2-CB 4.5Å; I234-I247 HydrophobicContact CG2-CD1 4.47Å; I234-I247 HydrophobicContact CG2-CG2 4.29Å
235	G	72.6	Confident	70	Confident	52 Å²	52	110.8 Å²	110.8	54%	0.536	54%	0.537	S	S	.	.	H	α-helix	trans	-65.8	-38.6	175.6	0	0	0	0	0	113.3	I231 W232 R233	I231-G235 PolarHBondContact O-N 3.32Å; W232-G235 PolarHBondContact O-N 2.86Å; R233-G235 PolarHBondContact O-N 3.5Å
236	A	71.3	Confident	68.1	Low	71 Å²	71	112.7 Å²	112.7	59%	0.587	55%	0.55	S	S	*	*	H	α-helix	trans	-74.4	-42	179.4	0	0	0	0	0	112.4	W232 R233 G238	W232-A236 PolarHBondContact O-N 3.26Å; R233-A236 PolarHBondContact O-N 3.36Å; R233-A236 VanDerWaalsContact O-N 3.07Å; A236-G238 PolarHBondContact O-N 3.46Å
237	D	68.3	Low	66.5	Low	121 Å²	121	110.5 Å²	110.5	65%	0.647	55%	0.547	S	S	*	.	H	α-helix	trans	-73.5	-12.4	179.6	-59.8	-26.4	0	0	0	112.4	R233 H239	R233-D237 VanDerWaalsContact O-CG 3.27Å; R233-D237 PolarHBondContact O-N 3.48Å; D237-H239 PolarHBondContact O-N 2.9Å
238	G	55.6	Low	65.2	Low	24 Å²	24	112 Å²	112	25%	0.247	56%	0.557	C	S	.	*	T	Hydrogen-bonded Turn	trans	-82.8	8.5	-170.6	0	0	0	0	0	117.2	I234 A236 T240	I234-G238 PolarHBondContact O-N 2.96Å; A236-G238 PolarHBondContact O-N 3.46Å; G238-T240 PolarHBondContact O-N 3.47Å
239	H	53.8	Low	64.1	Low	165 Å²	165	111.9 Å²	111.9	76%	0.764	56%	0.557	S	S	*	*	T	Hydrogen-bonded Turn	trans	-68.2	-19	175.7	-88.9	-85.5	0	0	0	113.5	D237	D237-H239 PolarHBondContact O-N 2.9Å
240	T	51.7	Low	62.9	Low	131 Å²	131	116.3 Å²	116.3	80%	0.804	57%	0.574	S	S	*	*	S	Bend	trans	-106.4	-17	-179.7	47.8	0	0	0	0	114.7	G238	G238-T240 PolarHBondContact O-N 3.47Å
241	V	52.1	Low	61.7	Low	94 Å²	94	117.7 Å²	117.7	57%	0.57	59%	0.589	S	S	*	*	S	Bend	trans	-117.9	31.4	-172.1	-165.9	0	0	0	0	112.2
242	R	47.7	Very low	61	Low	213 Å²	213	118.6 Å²	118.6	80%	0.804	59%	0.591	S	S	*	*			trans	-83.8	-9	-169.3	-164.5	167	173.9	-178.4	-3	115.5
243	R	46.8	Very low	60.5	Low	247 Å²	247	112.6 Å²	112.6	93%	0.932	58%	0.577	S	S	*	*	S	Bend	trans	-93	-11.3	-163.2	-133.3	176.4	-169.5	168.8	2.2	116.9
244	T	45.4	Very low	60	Low	128 Å²	128	108.3 Å²	108.3	79%	0.785	56%	0.562	S	S	*	*	S	Bend	trans	-135.5	-13.5	-171.7	26	0	0	0	0	117.5
245	M	47.3	Very low	59.7	Low	148 Å²	148	107.4 Å²	107.4	73%	0.729	56%	0.559	S	S	*	*			trans	-139.6	119	178.9	-59.2	-164.3	90.4	0	0	112.9	I247	M245-I247 HydrophobicContact CB-CG1 4.04Å; M245-I247 PolarHBondContact O-N 3.1Å
246	N	51.9	Low	60	Low	145 Å²	145	105.6 Å²	105.6	78%	0.775	54%	0.537	S	S	*	.			trans	-69.1	79.7	160	-85.2	-53.2	0	0	0	108.6	V248	N246-V248 PolarHBondContact O-N 2.95Å
247	I	57.4	Low	60.4	Low	91 Å²	91	108.2 Å²	108.2	47%	0.467	54%	0.535	S	S	.	.	S	Bend	trans	-57	-35.7	-174.3	-63.7	169.9	0	0	0	111.4	I234 M245	I234-I247 HydrophobicContact CD1-CG2 4.28Å; I234-I247 HydrophobicContact CG2-CB 4.5Å; I234-I247 HydrophobicContact CG2-CD1 4.47Å; I234-I247 HydrophobicContact CG2-CG2 4.29Å; M245-I247 HydrophobicContact CB-CG1 4.04Å; M245-I247 PolarHBondContact O-N 3.1Å
248	V	59.8	Low	60.9	Low	32 Å²	32	102.5 Å²	102.5	19%	0.194	50%	0.504	C	S	.	.	S	Bend	trans	-127	107.8	170.2	-175.2	0	0	0	0	109.8	N246 K252 V253	N246-V248 PolarHBondContact O-N 2.95Å; V248-K252 HydrophobicContact CG1-CB 3.95Å; V248-K252 HydrophobicContact CG1-CD 4.3Å; V248-V253 HydrophobicContact CG1-CG2 4.3Å
249	P	63.3	Low	62.1	Low	51 Å²	51	101.3 Å²	101.3	33%	0.331	49%	0.492	S	S	.	.			trans	-57.7	140.2	177.6	-25	32.5	0	0	0	112	T251 K252	P249-T251 PolarHBondContact O-N 2.87Å; P249-K252 HydrophobicContact CB-CG 4.48Å; P249-K252 HydrophobicContact CG-CG 4.47Å; P249-K252 WeakPolarHBondContact O-CB 3.36Å; P249-K252 PolarHBondContact O-N 3.38Å
250	R	64.5	Low	63.6	Low	223 Å²	223	97.5 Å²	97.5	84%	0.842	48%	0.477	S	S	*	.	H	α-helix	trans	-50.4	-32	174.9	-67.4	-176.2	177.7	-172.8	-1	112.9	K252 V253 K254	R250-K252 VanDerWaalsContact C-N 3.31Å; R250-K252 PolarHBondContact O-N 3.08Å; R250-V253 PolarHBondContact O-N 3.26Å; R250-K254 PolarHBondContact O-N 3.45Å; R250-K254 VanDerWaalsContact O-N 3.16Å
251	T	60.6	Low	65.2	Low	93 Å²	93	93.6 Å²	93.6	57%	0.571	45%	0.45	S	S	*	.	H	α-helix	trans	-59.5	-37.1	174.2	-43.6	0	0	0	0	112.8	P249 T255	P249-T251 PolarHBondContact O-N 2.87Å; T251-T255 PolarHBondContact O-N 2.73Å; T251-T255 PolarHBondContact O-OG1 2.92Å; T251-T255 VanDerWaalsContact O-OG1 3.13Å
252	K	68.1	Low	66.8	Low	57 Å²	57	89.5 Å²	89.5	25%	0.248	43%	0.425	C	S	.	.	H	α-helix	trans	-68	-41.5	177.1	-67.9	-164.5	180	-178.7	0	111.7	T148 I149 V248 P249 R250 K254 T255 I256	T148-K252 PolarHBondContact O-NZ 3.5Å; I149-K252 HydrophobicContact CG1-CD 4.49Å; V248-K252 HydrophobicContact CG1-CB 3.95Å; V248-K252 HydrophobicContact CG1-CD 4.3Å; P249-K252 HydrophobicContact CB-CG 4.48Å; P249-K252 HydrophobicContact CG-CG 4.47Å; P249-K252 WeakPolarHBondContact O-CB 3.36Å; P249-K252 PolarHBondContact O-N 3.38Å; R250-K252 VanDerWaalsContact C-N 3.31Å; R250-K252 PolarHBondContact O-N 3.08Å; K252-K254 VanDerWaalsContact C-N 3.34Å; K252-K254 PolarHBondContact O-N 3.27Å; K252-T255 PolarHBondContact O-N 3.48Å; K252-I256 VanDerWaalsContact O-CG1 3.29Å; K252-I256 WeakPolarHBondContact O-CG1 3.38Å; K252-I256 PolarHBondContact O-N 2.89Å
253	V	71.9	Confident	68.6	Low	71 Å²	71	79.6 Å²	79.6	43%	0.43	39%	0.388	S	S	.	.	H	α-helix	trans	-62.1	-42.7	177.3	179.1	0	0	0	0	111.2	V248 R250 T255 I256 K257	V248-V253 HydrophobicContact CG1-CG2 4.3Å; R250-V253 PolarHBondContact O-N 3.26Å; V253-T255 VanDerWaalsContact C-N 3.33Å; V253-T255 PolarHBondContact O-N 3.22Å; V253-I256 PolarHBondContact O-N 3.32Å; V253-K257 PolarHBondContact O-N 3.36Å
254	K	73.8	Confident	70.5	Confident	73 Å²	73	70.4 Å²	70.4	32%	0.317	36%	0.362	S	S	.	.	H	α-helix	trans	-61.3	-40.9	176.1	-172.9	171.8	171.3	175.3	0	112.2	R250 K252 K257 M258 V315 Y316	R250-K254 PolarHBondContact O-N 3.45Å; R250-K254 VanDerWaalsContact O-N 3.16Å; K252-K254 VanDerWaalsContact C-N 3.34Å; K252-K254 PolarHBondContact O-N 3.27Å; K254-K257 PolarHBondContact O-N 2.74Å; K254-M258 PolarHBondContact O-N 2.75Å; K254-V315 WeakPolarHBondContact CE-O 3.29Å; K254-V315 PolarHBondContact NZ-O 2.99Å; K254-Y316 HydrophobicContact CG-CD1 3.95Å
255	T	70.1	Confident	72.7	Confident	26 Å²	26	66.6 Å²	66.6	16%	0.16	34%	0.338	C	S	.	.	H	α-helix	trans	-67	-34.6	175.2	-59.9	0	0	0	0	112.6	T251 K252 V253 M258 F259	T251-T255 PolarHBondContact O-N 2.73Å; T251-T255 PolarHBondContact O-OG1 2.92Å; T251-T255 VanDerWaalsContact O-OG1 3.13Å; K252-T255 PolarHBondContact O-N 3.48Å; V253-T255 VanDerWaalsContact C-N 3.33Å; V253-T255 PolarHBondContact O-N 3.22Å; T255-M258 HydrophobicContact CG2-CE 4.33Å; T255-M258 WeakPolarHBondContact O-CB 3.44Å; T255-M258 PolarHBondContact O-N 3.4Å; T255-F259 HydrophobicContact CG2-CD2 3.81Å; T255-F259 HydrophobicContact CG2-CE2 3.37Å; T255-F259 HydrophobicContact CG2-CZ 4.2Å; T255-F259 WeakPolarHBondContact O-CD2 3.06Å; T255-F259 PolarHBondContact O-N 2.87Å; T255-F259 VanDerWaalsContact O-N 3.1Å
256	I	77.6	Confident	74.7	Confident	13 Å²	13	59.8 Å²	59.8	7%	0.067	31%	0.305	C	S	.	.	H	α-helix	trans	-66.8	-46.2	174.1	-62.9	159.4	0	0	0	110.5	I149 Y224 V227 I231 K252 V253 M258 F259 L260	I149-I256 HydrophobicContact CD1-CD1 3.39Å; I149-I256 HydrophobicContact CD1-CG1 3.66Å; Y224-I256 HydrophobicContact CD1-CG2 4.3Å; Y224-I256 HydrophobicContact CE1-CG2 4.43Å; V227-I256 HydrophobicContact CG1-CD1 3.87Å; V227-I256 HydrophobicContact CG1-CG1 4.42Å; I231-I256 HydrophobicContact CD1-CD1 3.42Å; I231-I256 VanDerWaalsContact CD1-CD1 3.42Å; K252-I256 VanDerWaalsContact O-CG1 3.29Å; K252-I256 WeakPolarHBondContact O-CG1 3.38Å; K252-I256 PolarHBondContact O-N 2.89Å; V253-I256 PolarHBondContact O-N 3.32Å; I256-M258 VanDerWaalsContact C-N 3.26Å; I256-M258 PolarHBondContact O-N 2.92Å; I256-F259 PolarHBondContact O-N 2.78Å; I256-F259 VanDerWaalsContact O-N 3.13Å; I256-L260 PolarHBondContact O-N 2.89Å
257	K	80.3	Confident	76.6	Confident	127 Å²	127	53.9 Å²	53.9	55%	0.552	27%	0.272	S	S	*	.	H	α-helix	trans	-58.1	-40.8	176.4	-173.8	178	177.7	-179.5	0	111.5	V253 K254 L260 M261 Y316	V253-K257 PolarHBondContact O-N 3.36Å; K254-K257 PolarHBondContact O-N 2.74Å; K257-L260 PolarHBondContact O-N 3.3Å; K257-M261 WeakPolarHBondContact O-CB 3.49Å; K257-M261 PolarHBondContact O-N 3.45Å; K257-Y316 HydrophobicContact CD-CE1 4.17Å; K257-Y316 HydrophobicContact CG-CE1 4.38Å
258	M	79.8	Confident	78.3	Confident	0 Å²	0	55.7 Å²	55.7	0%	0	28%	0.282	C	S	.	.	H	α-helix	trans	-55.9	-52.7	173.1	-173.5	-178.7	78.2	0	0	111.9	K254 T255 I256 M261 L262 Y313 Y316 N317	K254-M258 PolarHBondContact O-N 2.75Å; T255-M258 HydrophobicContact CG2-CE 4.33Å; T255-M258 WeakPolarHBondContact O-CB 3.44Å; T255-M258 PolarHBondContact O-N 3.4Å; I256-M258 VanDerWaalsContact C-N 3.26Å; I256-M258 PolarHBondContact O-N 2.92Å; M258-M261 PolarHBondContact O-N 3.24Å; M258-L262 HydrophobicContact CE-CD1 4.3Å; M258-L262 HydrophobicContact CG-CD1 3.87Å; M258-L262 WeakPolarHBondContact O-CG 3.3Å; M258-L262 PolarHBondContact O-N 3.16Å; M258-Y313 HydrophobicContact CE-CD1 4.45Å; M258-Y313 HydrophobicContact SD-CD1 4.15Å; M258-Y316 HydrophobicContact CB-CD1 4.42Å; M258-Y316 HydrophobicContact CB-CG 4.03Å; M258-Y316 VanDerWaalsContact CG-CB 3.44Å; M258-Y316 HydrophobicContact CG-CG 4.18Å; M258-N317 HydrophobicContact SD-CB 3.79Å
259	F	81.3	Confident	79.8	Confident	0 Å²	0	55 Å²	55	0%	0	28%	0.278	C	S	.	.	H	α-helix	trans	-67.9	-38.5	-177.5	-69.2	-53.7	0	0	0	112.2	T82 I141 R145 Y224 T255 I256 M261 L262 N263	T82-F259 HydrophobicContact CG2-CE1 4.41Å; T82-F259 HydrophobicContact CG2-CE2 4.27Å; T82-F259 HydrophobicContact CG2-CZ 3.51Å; I141-F259 HydrophobicContact CD1-CD1 4.42Å; I141-F259 HydrophobicContact CD1-CE1 3.97Å; I141-F259 HydrophobicContact CG1-CE1 4.42Å; I141-F259 HydrophobicContact CG2-CD1 3.65Å; I141-F259 HydrophobicContact CG2-CD2 3.81Å; I141-F259 HydrophobicContact CG2-CE1 3.56Å; I141-F259 HydrophobicContact CG2-CE2 3.69Å; I141-F259 HydrophobicContact CG2-CG 3.76Å; I141-F259 HydrophobicContact CG2-CZ 3.54Å; R145-F259 HydrophobicContact CG-CD2 3.93Å; R145-F259 HydrophobicContact CG-CE2 3.98Å; Y224-F259 HydrophobicContact CE1-CB 4.35Å; Y224-F259 WeakPolarHBondContact OH-CB 3.26Å; T255-F259 HydrophobicContact CG2-CD2 3.81Å; T255-F259 HydrophobicContact CG2-CE2 3.37Å; T255-F259 HydrophobicContact CG2-CZ 4.2Å; T255-F259 WeakPolarHBondContact O-CD2 3.06Å; T255-F259 PolarHBondContact O-N 2.87Å; T255-F259 VanDerWaalsContact O-N 3.1Å; I256-F259 PolarHBondContact O-N 2.78Å; I256-F259 VanDerWaalsContact O-N 3.13Å; F259-M261 VanDerWaalsContact C-N 3.31Å; F259-M261 PolarHBondContact O-N 2.88Å; F259-L262 HydrophobicContact CD1-CD1 3.96Å; F259-L262 HydrophobicContact CE1-CD1 4.5Å; F259-L262 PolarHBondContact O-N 3.44Å; F259-N263 WeakPolarHBondContact O-CB 3.5Å; F259-N263 PolarHBondContact O-N 3.35Å; F259-N263 PolarHBondContact O-ND2 2.87Å
260	L	84.6	Confident	81.3	Confident	84 Å²	84	52.7 Å²	52.7	44%	0.44	26%	0.263	S	S	.	.	H	α-helix	trans	-58.6	-46.5	174.8	-170.7	68.9	0	0	0	110.8	I256 K257 N263 S264	I256-L260 PolarHBondContact O-N 2.89Å; K257-L260 PolarHBondContact O-N 3.3Å; L260-N263 PolarHBondContact O-N 3.41Å; L260-S264 WeakPolarHBondContact O-CB 3.28Å; L260-S264 PolarHBondContact O-N 2.97Å; L260-S264 PolarHBondContact O-OG 3.16Å; L260-S264 VanDerWaalsContact O-OG 3.05Å
261	M	85.4	Confident	82.6	Confident	49 Å²	49	44.7 Å²	44.7	24%	0.241	24%	0.239	C	C	.	.	H	α-helix	trans	-63.8	-42.1	176.7	-174.7	-176.8	60	0	0	112.4	K257 M258 F259 S264 V265 L312 Y316	K257-M261 WeakPolarHBondContact O-CB 3.49Å; K257-M261 PolarHBondContact O-N 3.45Å; M258-M261 PolarHBondContact O-N 3.24Å; F259-M261 VanDerWaalsContact C-N 3.31Å; F259-M261 PolarHBondContact O-N 2.88Å; M261-S264 PolarHBondContact O-N 3.16Å; M261-V265 VanDerWaalsContact O-CG2 3.31Å; M261-V265 WeakPolarHBondContact O-CG2 3.31Å; M261-V265 PolarHBondContact O-N 3.48Å; M261-L312 HydrophobicContact CE-CB 3.89Å; M261-L312 HydrophobicContact CE-CD1 4.1Å; M261-L312 HydrophobicContact CE-CD2 3.2Å; M261-L312 HydrophobicContact CE-CG 3.86Å; M261-L312 HydrophobicContact SD-CD2 3.78Å; M261-Y316 HydrophobicContact CE-CD2 3.39Å; M261-Y316 HydrophobicContact CE-CE2 3.16Å; M261-Y316 HydrophobicContact CE-CG 4.37Å; M261-Y316 HydrophobicContact SD-CE2 3.79Å
262	L	84.3	Confident	84.1	Confident	8 Å²	8	42.7 Å²	42.7	4%	0.042	23%	0.227	C	C	.	.	H	α-helix	trans	-59.7	-46.2	174.6	-75.9	164	0	0	0	111.9	M258 F259 F266 K309 L312 Y313	M258-L262 HydrophobicContact CE-CD1 4.3Å; M258-L262 HydrophobicContact CG-CD1 3.87Å; M258-L262 WeakPolarHBondContact O-CG 3.3Å; M258-L262 PolarHBondContact O-N 3.16Å; F259-L262 HydrophobicContact CD1-CD1 3.96Å; F259-L262 HydrophobicContact CE1-CD1 4.5Å; F259-L262 PolarHBondContact O-N 3.44Å; L262-F266 VanDerWaalsContact O-CB 3.32Å; L262-F266 WeakPolarHBondContact O-CB 3.19Å; L262-F266 PolarHBondContact O-N 2.9Å; L262-K309 HydrophobicContact CD2-CB 4.39Å; L262-K309 HydrophobicContact CD2-CG 3.91Å; L262-L312 HydrophobicContact CD2-CB 4.01Å; L262-L312 HydrophobicContact CD2-CD1 3.5Å; L262-L312 HydrophobicContact CD2-CG 4.39Å; L262-L312 HydrophobicContact CG-CD1 4.17Å; L262-Y313 HydrophobicContact CD1-CD1 4.28Å; L262-Y313 HydrophobicContact CD1-CE1 3.56Å; L262-Y313 HydrophobicContact CD2-CE1 4.24Å
263	N	85.9	Confident	85.3	Confident	5 Å²	5	40.3 Å²	40.3	3%	0.027	22%	0.217	C	C	.	.	H	α-helix	trans	-62	-48.7	176.8	-79.7	-79.3	0	0	0	110.9	L138 Y224 F259 L260 V265 F266 F267	L138-N263 WeakPolarHBondContact CB-OD1 3.39Å; Y224-N263 WeakPolarHBondContact CE2-ND2 3.45Å; F259-N263 WeakPolarHBondContact O-CB 3.5Å; F259-N263 PolarHBondContact O-N 3.35Å; F259-N263 PolarHBondContact O-ND2 2.87Å; L260-N263 PolarHBondContact O-N 3.41Å; N263-V265 PolarHBondContact O-N 3.27Å; N263-F266 PolarHBondContact O-N 3.49Å; N263-F267 HydrophobicContact CB-CD2 4.18Å; N263-F267 HydrophobicContact CB-CE2 3.97Å; N263-F267 WeakPolarHBondContact O-CD2 3.41Å; N263-F267 WeakPolarHBondContact O-CG 3.06Å; N263-F267 PolarHBondContact O-N 3.37Å
264	S	87.7	Confident	86.2	Confident	55 Å²	55	37.7 Å²	37.7	39%	0.385	20%	0.199	S	C	.	.	H	α-helix	trans	-59.1	-49	179.5	-65.2	0	0	0	0	112.2	L260 M261 F266 F267 L268	L260-S264 WeakPolarHBondContact O-CB 3.28Å; L260-S264 PolarHBondContact O-N 2.97Å; L260-S264 PolarHBondContact O-OG 3.16Å; L260-S264 VanDerWaalsContact O-OG 3.05Å; M261-S264 PolarHBondContact O-N 3.16Å; S264-F266 VanDerWaalsContact C-N 3.34Å; S264-F266 PolarHBondContact O-N 3.39Å; S264-F267 PolarHBondContact O-N 3.33Å; S264-L268 VanDerWaalsContact O-CB 3.3Å; S264-L268 WeakPolarHBondContact O-CB 3.17Å; S264-L268 WeakPolarHBondContact O-CD1 3.47Å; S264-L268 WeakPolarHBondContact O-CG 3.33Å; S264-L268 PolarHBondContact O-N 2.87Å
265	V	90.1	Very high	87.1	Confident	48 Å²	48	37.9 Å²	37.9	29%	0.291	21%	0.207	S	C	.	.	H	α-helix	trans	-61.3	-44.9	178.9	171.8	0	0	0	0	110.7	M261 N263 T269	M261-V265 VanDerWaalsContact O-CG2 3.31Å; M261-V265 WeakPolarHBondContact O-CG2 3.31Å; M261-V265 PolarHBondContact O-N 3.48Å; N263-V265 PolarHBondContact O-N 3.27Å; V265-T269 HydrophobicContact CG1-CG2 4.48Å; V265-T269 WeakPolarHBondContact O-CB 3.45Å; V265-T269 VanDerWaalsContact O-CG2 3.27Å; V265-T269 WeakPolarHBondContact O-CG2 3.33Å; V265-T269 PolarHBondContact O-N 2.88Å; V265-T269 VanDerWaalsContact O-N 3.14Å; V265-T269 PolarHBondContact O-OG1 3.33Å
266	F	90.9	Very high	87.9	Confident	4 Å²	4	36.9 Å²	36.9	2%	0.018	20%	0.201	C	C	.	.	H	α-helix	trans	-61.3	-53.2	178.9	-179.1	-89.8	0	0	0	111.8	P131 Q134 V135 L138 L262 N263 S264 L268 T269 W270	P131-F266 HydrophobicContact CB-CZ 4.15Å; P131-F266 WeakPolarHBondContact O-CZ 3.24Å; Q134-F266 HydrophobicContact CB-CD2 4.48Å; Q134-F266 HydrophobicContact CB-CE2 3.75Å; Q134-F266 HydrophobicContact CB-CZ 3.93Å; Q134-F266 HydrophobicContact CG-CE2 4.37Å; V135-F266 HydrophobicContact CG2-CD1 4.46Å; V135-F266 HydrophobicContact CG2-CE1 3.41Å; V135-F266 VanDerWaalsContact CG2-CE1 3.41Å; V135-F266 HydrophobicContact CG2-CZ 3.89Å; L138-F266 HydrophobicContact CD1-CB 4.21Å; L138-F266 HydrophobicContact CD1-CD1 3.97Å; L138-F266 HydrophobicContact CD1-CG 4.02Å; L262-F266 VanDerWaalsContact O-CB 3.32Å; L262-F266 WeakPolarHBondContact O-CB 3.19Å; L262-F266 PolarHBondContact O-N 2.9Å; N263-F266 PolarHBondContact O-N 3.49Å; S264-F266 VanDerWaalsContact C-N 3.34Å; S264-F266 PolarHBondContact O-N 3.39Å; F266-L268 PolarHBondContact O-N 3.38Å; F266-T269 PolarHBondContact O-N 2.82Å; F266-T269 PolarHBondContact O-OG1 2.92Å; F266-W270 AromaticContact CD2-CD1 3.51Å; F266-W270 HydrophobicContact CD2-CG 4.45Å; F266-W270 AromaticContact CD2-NE1 3.68Å; F266-W270 HydrophobicContact CE1-CB 4.47Å; F266-W270 HydrophobicContact CE1-CG 4.34Å; F266-W270 AromaticContact CE2-CD1 3.38Å; F266-W270 HydrophobicContact CE2-CD2 4.4Å; F266-W270 HydrophobicContact CE2-CG 4.02Å; F266-W270 AromaticContact CE2-NE1 3.35Å; F266-W270 AromaticContact CZ-CD1 3.76Å; F266-W270 HydrophobicContact CZ-CD2 4.4Å; F266-W270 AromaticContact CZ-CG 3.96Å; F266-W270 HydrophobicContact CZ-CG 3.96Å; F266-W270 WeakPolarHBondContact O-CB 3.47Å; F266-W270 VanDerWaalsContact O-CD1 3.26Å; F266-W270 PolarHBondContact O-N 3.48Å
267	F	91.9	Very high	88.5	Confident	21 Å²	21	36.6 Å²	36.6	9%	0.092	20%	0.2	C	C	.	.	H	α-helix	trans	-66.4	-40	-176.3	-66.3	-54.8	0	0	0	112.8	V135 F213 V217 I220 N263 S264 T269 T271	V135-F267 HydrophobicContact CG1-CE1 4.38Å; V135-F267 HydrophobicContact CG2-CE1 4.1Å; F213-F267 HydrophobicContact CD2-CD1 4.2Å; F213-F267 HydrophobicContact CD2-CE1 4.42Å; F213-F267 AromaticContact CE2-CD1 3.5Å; F213-F267 HydrophobicContact CE2-CD1 3.5Å; F213-F267 HydrophobicContact CE2-CE1 4.13Å; F213-F267 HydrophobicContact CZ-CB 4.2Å; F213-F267 AromaticContact CZ-CD1 3.71Å; F213-F267 HydrophobicContact CZ-CD1 3.71Å; F213-F267 HydrophobicContact CZ-CG 4.45Å; V217-F267 HydrophobicContact CB-CE1 4.49Å; V217-F267 HydrophobicContact CG2-CD1 3.24Å; V217-F267 HydrophobicContact CG2-CD2 4.03Å; V217-F267 HydrophobicContact CG2-CE1 3.19Å; V217-F267 HydrophobicContact CG2-CE2 4.01Å; V217-F267 HydrophobicContact CG2-CG 3.7Å; V217-F267 HydrophobicContact CG2-CZ 3.62Å; I220-F267 HydrophobicContact CD1-CE2 3.97Å; I220-F267 HydrophobicContact CD1-CZ 3.57Å; I220-F267 HydrophobicContact CG2-CE2 4.49Å; N263-F267 HydrophobicContact CB-CD2 4.18Å; N263-F267 HydrophobicContact CB-CE2 3.97Å; N263-F267 WeakPolarHBondContact O-CD2 3.41Å; N263-F267 WeakPolarHBondContact O-CG 3.06Å; N263-F267 PolarHBondContact O-N 3.37Å; S264-F267 PolarHBondContact O-N 3.33Å; F267-T269 VanDerWaalsContact C-N 3.33Å; F267-T269 PolarHBondContact O-N 2.93Å; F267-T271 WeakPolarHBondContact O-CB 3.41Å; F267-T271 PolarHBondContact O-N 3.01Å; F267-T271 PolarHBondContact O-OG1 3.48Å
268	L	92.3	Very high	88.8	Confident	129 Å²	129	33.6 Å²	33.6	68%	0.675	19%	0.189	S	C	*	.	H	α-helix	trans	-63.5	-39.3	177.9	-70.2	171.8	0	0	0	112.4	S264 F266 P272	S264-L268 VanDerWaalsContact O-CB 3.3Å; S264-L268 WeakPolarHBondContact O-CB 3.17Å; S264-L268 WeakPolarHBondContact O-CD1 3.47Å; S264-L268 WeakPolarHBondContact O-CG 3.33Å; S264-L268 PolarHBondContact O-N 2.87Å; F266-L268 PolarHBondContact O-N 3.38Å; L268-P272 WeakPolarHBondContact O-CD 3.36Å
269	T	92.4	Very high	89	Confident	18 Å²	18	41.1 Å²	41.1	11%	0.11	22%	0.218	C	C	.	.	H	α-helix	trans	-79.8	-29.2	-177.6	52.3	0	0	0	0	113.5	V265 F266 F267 P272 V301 C302 S305	V265-T269 HydrophobicContact CG1-CG2 4.48Å; V265-T269 WeakPolarHBondContact O-CB 3.45Å; V265-T269 VanDerWaalsContact O-CG2 3.27Å; V265-T269 WeakPolarHBondContact O-CG2 3.33Å; V265-T269 PolarHBondContact O-N 2.88Å; V265-T269 VanDerWaalsContact O-N 3.14Å; V265-T269 PolarHBondContact O-OG1 3.33Å; F266-T269 PolarHBondContact O-N 2.82Å; F266-T269 PolarHBondContact O-OG1 2.92Å; F267-T269 VanDerWaalsContact C-N 3.33Å; F267-T269 PolarHBondContact O-N 2.93Å; T269-P272 WeakPolarHBondContact O-CD 3.41Å; T269-V301 HydrophobicContact CG2-CG1 3.95Å; T269-C302 PolarHBondContact O-SG 3.01Å; T269-C302 VanDerWaalsContact O-SG 3.41Å; T269-S305 WeakPolarHBondContact OG1-CB 2.85Å
270	W	93.5	Very high	88.7	Confident	2 Å²	2	43.1 Å²	43.1	1%	0.008	23%	0.227	C	C	.	.	H	α-helix	trans	-91.8	-18.5	179.8	-77.7	88.4	0	0	0	114.2	M96 W100 P131 F213 F266 P272 F273 Y274 C302 S305	M96-W270 HydrophobicContact CE-CZ2 4.41Å; M96-W270 HydrophobicContact SD-CH2 3.93Å; M96-W270 HydrophobicContact SD-CZ2 3.61Å; W100-W270 HydrophobicContact CZ2-CH2 4.22Å; P131-W270 HydrophobicContact CB-CD2 3.85Å; P131-W270 HydrophobicContact CB-CE3 3.6Å; P131-W270 HydrophobicContact CB-CH2 3.6Å; P131-W270 HydrophobicContact CB-CZ2 3.84Å; P131-W270 HydrophobicContact CB-CZ3 3.49Å; P131-W270 VanDerWaalsContact CB-CZ3 3.49Å; P131-W270 HydrophobicContact CG-CE3 4.01Å; P131-W270 HydrophobicContact CG-CH2 3.66Å; P131-W270 HydrophobicContact CG-CZ2 4.38Å; P131-W270 HydrophobicContact CG-CZ3 3.46Å; P131-W270 VanDerWaalsContact CG-CZ3 3.46Å; F213-W270 HydrophobicContact CE2-CB 4.11Å; F266-W270 AromaticContact CD2-CD1 3.51Å; F266-W270 HydrophobicContact CD2-CG 4.45Å; F266-W270 AromaticContact CD2-NE1 3.68Å; F266-W270 HydrophobicContact CE1-CB 4.47Å; F266-W270 HydrophobicContact CE1-CG 4.34Å; F266-W270 AromaticContact CE2-CD1 3.38Å; F266-W270 HydrophobicContact CE2-CD2 4.4Å; F266-W270 HydrophobicContact CE2-CG 4.02Å; F266-W270 AromaticContact CE2-NE1 3.35Å; F266-W270 AromaticContact CZ-CD1 3.76Å; F266-W270 HydrophobicContact CZ-CD2 4.4Å; F266-W270 AromaticContact CZ-CG 3.96Å; F266-W270 HydrophobicContact CZ-CG 3.96Å; F266-W270 WeakPolarHBondContact O-CB 3.47Å; F266-W270 VanDerWaalsContact O-CD1 3.26Å; F266-W270 PolarHBondContact O-N 3.48Å; W270-P272 VanDerWaalsContact C-CD 3.49Å; W270-F273 HydrophobicContact CE3-CB 4.11Å; W270-F273 AromaticContact CE3-CD1 3.9Å; W270-F273 HydrophobicContact CE3-CD1 3.9Å; W270-F273 HydrophobicContact CE3-CG 4.1Å; W270-F273 AromaticContact CZ3-CD1 3.93Å; W270-F273 HydrophobicContact CZ3-CD1 3.93Å; W270-F273 HydrophobicContact CZ3-CE1 4.35Å; W270-F273 HydrophobicContact CZ3-CG 4.14Å; W270-F273 WeakPolarHBondContact O-CB 3.3Å; W270-F273 PolarHBondContact O-N 2.92Å; W270-Y274 HydrophobicContact CB-CD2 4.39Å; W270-Y274 HydrophobicContact CB-CE2 4.2Å; W270-Y274 HydrophobicContact CE3-CE2 4.5Å; W270-Y274 VanDerWaalsContact O-CD2 3.31Å; W270-Y274 WeakPolarHBondContact O-CD2 2.94Å; W270-Y274 PolarHBondContact O-N 2.85Å; W270-C302 HydrophobicContact CD2-CB 4.16Å; W270-C302 HydrophobicContact CE3-CB 4.33Å; W270-C302 HydrophobicContact CH2-CB 4.1Å; W270-C302 HydrophobicContact CZ2-CB 3.9Å; W270-C302 HydrophobicContact CZ3-CB 4.3Å; W270-S305 PolarHBondContact NE1-OG 3.37Å
271	T	92.6	Very high	87.9	Confident	55 Å²	55	40.7 Å²	40.7	34%	0.337	22%	0.216	S	C	.	.	H	α-helix	trans	-52.8	-47.2	176.2	-62.6	0	0	0	0	112.7	F213 F267 F273 Y274 V275	F213-T271 WeakPolarHBondContact CE1-OG1 3.2Å; F213-T271 WeakPolarHBondContact CZ-OG1 3.39Å; F267-T271 WeakPolarHBondContact O-CB 3.41Å; F267-T271 PolarHBondContact O-N 3.01Å; F267-T271 PolarHBondContact O-OG1 3.48Å; T271-F273 PolarHBondContact O-N 2.74Å; T271-Y274 PolarHBondContact O-N 3.06Å; T271-V275 HydrophobicContact CG2-CG2 4.03Å; T271-V275 WeakPolarHBondContact O-CG2 3.48Å; T271-V275 PolarHBondContact O-N 3.01Å
272	P	92.6	Very high	86.8	Confident	52 Å²	52	46.9 Å²	46.9	34%	0.338	24%	0.244	S	C	.	.	H	α-helix	trans	-57.6	-35.6	178.1	-24.6	34.8	0	0	0	113	L268 T269 W270 A276 I298	L268-P272 WeakPolarHBondContact O-CD 3.36Å; T269-P272 WeakPolarHBondContact O-CD 3.41Å; W270-P272 VanDerWaalsContact C-CD 3.49Å; P272-A276 WeakPolarHBondContact O-CB 2.98Å; P272-A276 PolarHBondContact O-N 3.35Å; P272-I298 HydrophobicContact CB-CG1 4.2Å; P272-I298 HydrophobicContact CB-CG2 4.49Å
273	F	91.6	Very high	85.3	Confident	7 Å²	7	53.6 Å²	53.6	3%	0.031	28%	0.276	C	S	.	.	H	α-helix	trans	-64.5	-52.8	177.3	178.4	-99.4	0	0	0	111.7	Q127 W270 T271 V275 A276 Q277 F295 I298	Q127-F273 HydrophobicContact CG-CE2 4.36Å; Q127-F273 HydrophobicContact CG-CZ 4.02Å; W270-F273 HydrophobicContact CE3-CB 4.11Å; W270-F273 AromaticContact CE3-CD1 3.9Å; W270-F273 HydrophobicContact CE3-CD1 3.9Å; W270-F273 HydrophobicContact CE3-CG 4.1Å; W270-F273 AromaticContact CZ3-CD1 3.93Å; W270-F273 HydrophobicContact CZ3-CD1 3.93Å; W270-F273 HydrophobicContact CZ3-CE1 4.35Å; W270-F273 HydrophobicContact CZ3-CG 4.14Å; W270-F273 WeakPolarHBondContact O-CB 3.3Å; W270-F273 PolarHBondContact O-N 2.92Å; T271-F273 PolarHBondContact O-N 2.74Å; F273-V275 VanDerWaalsContact C-N 3.3Å; F273-V275 PolarHBondContact O-N 3.35Å; F273-A276 PolarHBondContact O-N 2.98Å; F273-Q277 HydrophobicContact CE1-CG 4.21Å; F273-Q277 HydrophobicContact CE2-CG 4.41Å; F273-Q277 VanDerWaalsContact CE2-NE2 3.31Å; F273-Q277 HydrophobicContact CZ-CG 4.08Å; F273-Q277 WeakPolarHBondContact O-CG 3.42Å; F273-Q277 PolarHBondContact O-N 3.3Å; F273-Q277 VanDerWaalsContact O-N 3.12Å; F273-F295 HydrophobicContact CE2-CE2 4.5Å; F273-I298 HydrophobicContact CB-CG2 3.81Å; F273-I298 HydrophobicContact CD2-CG2 4.12Å
274	Y	91.7	Very high	83.9	Confident	15 Å²	15	58.8 Å²	58.8	6%	0.059	31%	0.307	C	S	.	.	H	α-helix	trans	-63.4	-36.2	-179.7	-73.7	-81.9	0	0	0	112.6	F213 W270 T271	F213-Y274 HydrophobicContact CB-CD1 4.15Å; F213-Y274 HydrophobicContact CB-CD2 4.2Å; F213-Y274 HydrophobicContact CB-CE1 4.15Å; F213-Y274 HydrophobicContact CB-CE2 4.23Å; F213-Y274 HydrophobicContact CB-CG 4.18Å; F213-Y274 HydrophobicContact CD1-CD2 4.27Å; F213-Y274 AromaticContact CD2-CD2 3.41Å; F213-Y274 HydrophobicContact CD2-CD2 3.41Å; F213-Y274 VanDerWaalsContact CD2-CD2 3.41Å; F213-Y274 AromaticContact CD2-CE2 3.18Å; F213-Y274 HydrophobicContact CD2-CE2 3.18Å; F213-Y274 HydrophobicContact CD2-CG 4.21Å; F213-Y274 AromaticContact CD2-CZ 3.81Å; F213-Y274 HydrophobicContact CE1-CD2 4.49Å; F213-Y274 AromaticContact CE2-CD2 3.64Å; F213-Y274 HydrophobicContact CE2-CD2 3.64Å; F213-Y274 AromaticContact CE2-CE2 3.57Å; F213-Y274 HydrophobicContact CE2-CE2 3.57Å; F213-Y274 AromaticContact CG-CD2 3.73Å; F213-Y274 HydrophobicContact CG-CD2 3.73Å; F213-Y274 AromaticContact CG-CE2 3.87Å; F213-Y274 HydrophobicContact CG-CE2 3.87Å; F213-Y274 HydrophobicContact CG-CG 4.09Å; F213-Y274 HydrophobicContact CZ-CD2 4.2Å; W270-Y274 HydrophobicContact CB-CD2 4.39Å; W270-Y274 HydrophobicContact CB-CE2 4.2Å; W270-Y274 HydrophobicContact CE3-CE2 4.5Å; W270-Y274 VanDerWaalsContact O-CD2 3.31Å; W270-Y274 WeakPolarHBondContact O-CD2 2.94Å; W270-Y274 PolarHBondContact O-N 2.85Å; T271-Y274 PolarHBondContact O-N 3.06Å
275	V	91.6	Very high	82.4	Confident	77 Å²	77	62.9 Å²	62.9	47%	0.467	33%	0.325	S	S	.	.	H	α-helix	trans	-69.5	-41.8	175.5	176	0	0	0	0	111	T271 F273 Q277 L278	T271-V275 HydrophobicContact CG2-CG2 4.03Å; T271-V275 WeakPolarHBondContact O-CG2 3.48Å; T271-V275 PolarHBondContact O-N 3.01Å; F273-V275 VanDerWaalsContact C-N 3.3Å; F273-V275 PolarHBondContact O-N 3.35Å; V275-Q277 PolarHBondContact O-N 3.1Å; V275-L278 WeakPolarHBondContact O-CB 3.11Å; V275-L278 PolarHBondContact O-N 3.37Å; V275-L278 VanDerWaalsContact O-N 3.08Å
276	A	88.6	Confident	81.2	Confident	6 Å²	6	65.1 Å²	65.1	5%	0.05	34%	0.339	C	S	.	.	H	α-helix	trans	-66.4	-24.8	179.9	0	0	0	0	0	113	F194 P272 F273 L278 W279 F294 I298	F194-A276 WeakPolarHBondContact CD1-O 3.03Å; F194-A276 HydrophobicContact CE1-CB 4.16Å; P272-A276 WeakPolarHBondContact O-CB 2.98Å; P272-A276 PolarHBondContact O-N 3.35Å; F273-A276 PolarHBondContact O-N 2.98Å; A276-L278 PolarHBondContact O-N 3.07Å; A276-W279 WeakPolarHBondContact O-CB 2.93Å; A276-W279 PolarHBondContact O-N 3.24Å; A276-F294 HydrophobicContact CB-CE1 3.84Å; A276-F294 HydrophobicContact CB-CZ 4.21Å; A276-I298 HydrophobicContact CB-CD1 3.52Å
277	Q	88.8	Confident	80	Confident	7 Å²	7	67.7 Å²	67.7	3%	0.033	36%	0.356	C	S	.	.	T	Hydrogen-bonded Turn	trans	-70.3	-13.6	173.5	-65.5	-55.9	-31	0	0	113.9	F193 A205 F273 V275 W279	F193-Q277 PolarHBondContact O-NE2 3.48Å; A205-Q277 HydrophobicContact CB-CB 4.47Å; A205-Q277 WeakPolarHBondContact CB-O 3.43Å; F273-Q277 HydrophobicContact CE1-CG 4.21Å; F273-Q277 HydrophobicContact CE2-CG 4.41Å; F273-Q277 VanDerWaalsContact CE2-NE2 3.31Å; F273-Q277 HydrophobicContact CZ-CG 4.08Å; F273-Q277 WeakPolarHBondContact O-CG 3.42Å; F273-Q277 PolarHBondContact O-N 3.3Å; F273-Q277 VanDerWaalsContact O-N 3.12Å; V275-Q277 PolarHBondContact O-N 3.1Å; Q277-W279 VanDerWaalsContact C-N 3.32Å
278	L	87.6	Confident	79.1	Confident	63 Å²	63	69.1 Å²	69.1	33%	0.33	37%	0.369	S	S	.	.	T	Hydrogen-bonded Turn	trans	-83	-11.9	168.4	-72	157	0	0	0	112.5	A205 A206 L209 V275 A276 H280	A205-L278 HydrophobicContact CB-CD2 4.27Å; A206-L278 HydrophobicContact CB-CD2 4.19Å; L209-L278 HydrophobicContact CD2-CD1 3.52Å; V275-L278 WeakPolarHBondContact O-CB 3.11Å; V275-L278 PolarHBondContact O-N 3.37Å; V275-L278 VanDerWaalsContact O-N 3.08Å; A276-L278 PolarHBondContact O-N 3.07Å; L278-H280 PolarHBondContact O-CD2 3.48Å; L278-H280 PolarHBondContact O-N 2.88Å
279	W	83.8	Confident	78.3	Confident	159 Å²	159	67 Å²	67	60%	0.602	35%	0.352	S	S	*	.			trans	-79.1	119.3	175.4	-171.7	-92.6	0	0	0	108.9	A276 Q277 P281	A276-W279 WeakPolarHBondContact O-CB 2.93Å; A276-W279 PolarHBondContact O-N 3.24Å; Q277-W279 VanDerWaalsContact C-N 3.32Å; W279-P281 WeakPolarHBondContact O-CD 3.39Å
280	H	74.3	Confident	77.6	Confident	42 Å²	42	74.6 Å²	74.6	19%	0.194	38%	0.383	C	S	.	.			trans	-114.7	93.7	178.4	-62.2	-68.5	0	0	0	108.7	L195 I202 L278	L195-H280 PolarHBondContact O-ND1 3.36Å; I202-H280 VanDerWaalsContact CG1-CD2 3.44Å; I202-H280 WeakPolarHBondContact CG1-CD2 3.23Å; I202-H280 WeakPolarHBondContact CG1-NE2 3.22Å; L278-H280 PolarHBondContact O-CD2 3.48Å; L278-H280 PolarHBondContact O-N 2.88Å
281	P	68.4	Low	76.9	Confident	32 Å²	32	76.6 Å²	76.6	21%	0.208	39%	0.393	C	S	.	.			trans	-67.2	140.1	173.6	27.4	-27.5	0	0	0	109.5	F194 W279 E291	F194-P281 HydrophobicContact CD2-CG 4.28Å; W279-P281 WeakPolarHBondContact O-CD 3.39Å; P281-E291 WeakPolarHBondContact CB-OE1 3.09Å
282	E	61.9	Low	76.2	Confident	179 Å²	179	75 Å²	75	84%	0.836	38%	0.382	S	S	*	.			trans	-64.4	135.5	171.2	-77.7	-173.3	159.7	0	0	109.4	V284	E282-V284 PolarHBondContact O-N 3.33Å
283	E	53.8	Low	75.6	Confident	150 Å²	150	75.1 Å²	75.1	70%	0.701	38%	0.379	S	S	*	.			trans	-57.3	103.7	-173	-68.7	-176.6	176.1	0	0	111.6
284	V	55.9	Low	75.2	Confident	113 Å²	113	79.6 Å²	79.6	69%	0.685	40%	0.399	S	S	*	.			trans	-106.2	127.8	152.8	-177.5	0	0	0	0	105.5	E282 T286	E282-V284 PolarHBondContact O-N 3.33Å; V284-T286 CarbonylContact O-C 3.6Å; V284-T286 PolarHBondContact O-N 3.04Å
285	N	57.3	Low	74.8	Confident	141 Å²	141	79.1 Å²	79.1	75%	0.754	40%	0.397	S	S	*	.	S	Bend	trans	-52.6	-7.5	-174	-68.2	-31	0	0	0	115.5
286	T	62.8	Low	74.3	Confident	96 Å²	96	76.1 Å²	76.1	59%	0.589	38%	0.379	S	S	*	.	S	Bend	trans	-132.9	129.8	170.9	47.8	0	0	0	0	109.7	V284 S288	V284-T286 CarbonylContact O-C 3.6Å; V284-T286 PolarHBondContact O-N 3.04Å; T286-S288 PolarHBondContact O-N 2.9Å
287	P	66.1	Low	74.1	Confident	57 Å²	57	79.5 Å²	79.5	37%	0.37	40%	0.399	S	S	.	.			trans	-60	130.4	174.1	23.4	-30.7	0	0	0	108.9	E291	P287-E291 HydrophobicContact CB-CB 4.46Å
288	S	73.4	Confident	74	Confident	52 Å²	52	79.6 Å²	79.6	36%	0.364	40%	0.4	S	S	.	.			trans	-59.8	151.9	176.2	68.3	0	0	0	0	110.3	T286 K290 E291 L292	T286-S288 PolarHBondContact O-N 2.9Å; S288-K290 PolarHBondContact O-N 3.22Å; S288-E291 WeakPolarHBondContact CB-OE2 3.42Å; S288-E291 PolarHBondContact N-OE2 2.86Å; S288-E291 PolarHBondContact O-N 3.35Å; S288-E291 VanDerWaalsContact OG-CG 3.29Å; S288-E291 WeakPolarHBondContact OG-CG 3.12Å; S288-E291 PolarHBondContact OG-N 2.83Å; S288-E291 PolarHBondContact OG-OE2 3.22Å; S288-L292 PolarHBondContact O-N 2.75Å
289	R	75.1	Confident	73.9	Confident	85 Å²	85	77 Å²	77	32%	0.321	39%	0.387	S	S	.	.	H	α-helix	trans	-46.9	-38.6	174.2	-174.4	176.1	169.2	165.9	-0.4	112.6	G40 D41 L42 E46 L293	G40-R289 WeakPolarHBondContact O-CB 3.46Å; G40-R289 WeakPolarHBondContact O-CD 3.48Å; D41-R289 PolarHBondContact O-NH1 2.02Å; L42-R289 HydrophobicContact CD1-CG 4.28Å; E46-R289 IonicContact OE1-NH2 3.04Å; E46-R289 PolarHBondContact OE1-NH2 2.77Å; E46-R289 IonicContact OE2-CZ 2.79Å; E46-R289 IonicContact OE2-NH2 3.93Å; E46-R289 PolarHBondContact OE2-NH2 2.86Å; R289-L293 HydrophobicContact CG-CD1 4.01Å; R289-L293 HydrophobicContact CG-CG 4.49Å; R289-L293 WeakPolarHBondContact O-CB 3.27Å; R289-L293 VanDerWaalsContact O-CG 3.25Å; R289-L293 WeakPolarHBondContact O-CG 3.31Å; R289-L293 PolarHBondContact O-N 2.98Å
290	K	78.1	Confident	73.9	Confident	176 Å²	176	71.8 Å²	71.8	77%	0.765	37%	0.367	S	S	*	.	H	α-helix	trans	-67.1	-42.5	-179.8	-65.4	-178.3	-177	175.9	0	111.7	S288 F294	S288-K290 PolarHBondContact O-N 3.22Å; K290-F294 WeakPolarHBondContact O-CB 3.18Å; K290-F294 PolarHBondContact O-N 3.09Å
291	E	78.2	Confident	74.6	Confident	45 Å²	45	72.5 Å²	72.5	21%	0.21	37%	0.374	C	S	.	.	H	α-helix	trans	-67.8	-41.1	177.5	-71.6	157.5	158.5	0	0	111.6	P281 P287 S288 F294 F295	P281-E291 WeakPolarHBondContact CB-OE1 3.09Å; P287-E291 HydrophobicContact CB-CB 4.46Å; S288-E291 WeakPolarHBondContact CB-OE2 3.42Å; S288-E291 PolarHBondContact N-OE2 2.86Å; S288-E291 PolarHBondContact O-N 3.35Å; S288-E291 VanDerWaalsContact OG-CG 3.29Å; S288-E291 WeakPolarHBondContact OG-CG 3.12Å; S288-E291 PolarHBondContact OG-N 2.83Å; S288-E291 PolarHBondContact OG-OE2 3.22Å; E291-F294 PolarHBondContact O-N 3.2Å; E291-F295 WeakPolarHBondContact O-CB 3.31Å; E291-F295 PolarHBondContact O-N 3.18Å
292	L	78.3	Confident	75.6	Confident	22 Å²	22	71 Å²	71	12%	0.115	37%	0.365	C	S	.	.	H	α-helix	trans	-62	-47.3	175.8	-173.2	63.9	0	0	0	111.6	L42 V108 F193 S288 T296	L42-L292 HydrophobicContact CD1-CD2 3.78Å; V108-L292 HydrophobicContact CB-CD1 4.23Å; V108-L292 HydrophobicContact CG1-CD1 4.02Å; V108-L292 HydrophobicContact CG1-CD2 4.39Å; V108-L292 HydrophobicContact CG1-CG 4.34Å; V108-L292 HydrophobicContact CG2-CD1 3.82Å; F193-L292 HydrophobicContact CE2-CD1 3.89Å; F193-L292 HydrophobicContact CZ-CD1 4.22Å; S288-L292 PolarHBondContact O-N 2.75Å; L292-T296 VanDerWaalsContact O-CB 3.24Å; L292-T296 WeakPolarHBondContact O-CB 3.19Å; L292-T296 PolarHBondContact O-N 3.42Å; L292-T296 PolarHBondContact O-OG1 3.44Å
293	L	80.4	Confident	76.7	Confident	53 Å²	53	62.6 Å²	62.6	28%	0.277	33%	0.326	S	S	.	.	H	α-helix	trans	-63.6	-42.7	176.4	-75.2	172.8	0	0	0	111.9	L42 L50 R289 T296 T297	L42-L293 HydrophobicContact CD2-CD2 3.7Å; L42-L293 HydrophobicContact CG-CD2 4.2Å; L50-L293 HydrophobicContact CD1-CD2 4.48Å; R289-L293 HydrophobicContact CG-CD1 4.01Å; R289-L293 HydrophobicContact CG-CG 4.49Å; R289-L293 WeakPolarHBondContact O-CB 3.27Å; R289-L293 VanDerWaalsContact O-CG 3.25Å; R289-L293 WeakPolarHBondContact O-CG 3.31Å; R289-L293 PolarHBondContact O-N 2.98Å; L293-T296 PolarHBondContact O-N 2.89Å; L293-T297 WeakPolarHBondContact O-CB 3.34Å; L293-T297 PolarHBondContact O-N 3.36Å; L293-T297 PolarHBondContact O-OG1 3.41Å
294	F	83.1	Confident	78.3	Confident	102 Å²	102	57.2 Å²	57.2	45%	0.447	31%	0.305	S	S	.	.	H	α-helix	trans	-61	-51.3	177.6	179.8	-112	0	0	0	111.5	F194 A276 K290 E291 T296 T297 I298	F194-F294 HydrophobicContact CZ-CD1 4.11Å; F194-F294 HydrophobicContact CZ-CE1 4.48Å; A276-F294 HydrophobicContact CB-CE1 3.84Å; A276-F294 HydrophobicContact CB-CZ 4.21Å; K290-F294 WeakPolarHBondContact O-CB 3.18Å; K290-F294 PolarHBondContact O-N 3.09Å; E291-F294 PolarHBondContact O-N 3.2Å; F294-T296 PolarHBondContact O-N 2.95Å; F294-T297 PolarHBondContact O-N 3.27Å; F294-I298 HydrophobicContact CD1-CD1 3.87Å; F294-I298 HydrophobicContact CD2-CD1 4.31Å; F294-I298 HydrophobicContact CE1-CD1 3.46Å; F294-I298 VanDerWaalsContact CE1-CD1 3.46Å; F294-I298 HydrophobicContact CE2-CD1 3.94Å; F294-I298 HydrophobicContact CG-CD1 4.28Å; F294-I298 HydrophobicContact CZ-CD1 3.51Å; F294-I298 WeakPolarHBondContact O-CG1 3.28Å; F294-I298 PolarHBondContact O-N 3.27Å
295	F	83.3	Confident	79.9	Confident	4 Å²	4	52 Å²	52	2%	0.018	27%	0.273	C	S	.	.	H	α-helix	trans	-62.5	-44.2	177.9	-177.9	-92.4	0	0	0	111.9	V104 F193 F194 F273 E291 T297 I298 A299	V104-F295 HydrophobicContact CG1-CE1 3.65Å; V104-F295 HydrophobicContact CG1-CZ 4.44Å; F193-F295 HydrophobicContact CB-CD1 4.29Å; F193-F295 HydrophobicContact CB-CD2 3.69Å; F193-F295 HydrophobicContact CB-CE1 4.44Å; F193-F295 HydrophobicContact CB-CE2 3.85Å; F193-F295 HydrophobicContact CB-CG 3.93Å; F193-F295 HydrophobicContact CB-CZ 4.24Å; F193-F295 AromaticContact CD1-CD1 3.45Å; F193-F295 HydrophobicContact CD1-CD1 3.45Å; F193-F295 VanDerWaalsContact CD1-CD1 3.45Å; F193-F295 HydrophobicContact CD1-CD2 4.24Å; F193-F295 AromaticContact CD1-CE1 3.2Å; F193-F295 HydrophobicContact CD1-CE1 3.2Å; F193-F295 HydrophobicContact CD1-CE2 4.02Å; F193-F295 AromaticContact CD1-CG 3.98Å; F193-F295 HydrophobicContact CD1-CG 3.98Å; F193-F295 AromaticContact CD1-CZ 3.52Å; F193-F295 HydrophobicContact CD1-CZ 3.52Å; F193-F295 AromaticContact CE1-CD1 3.81Å; F193-F295 HydrophobicContact CE1-CD1 3.81Å; F193-F295 AromaticContact CE1-CE1 3.58Å; F193-F295 HydrophobicContact CE1-CE1 3.58Å; F193-F295 HydrophobicContact CE1-CZ 4.28Å; F193-F295 AromaticContact CG-CD1 3.87Å; F193-F295 HydrophobicContact CG-CD1 3.87Å; F193-F295 HydrophobicContact CG-CD2 4.19Å; F193-F295 HydrophobicContact CG-CE1 4.03Å; F193-F295 HydrophobicContact CG-CE2 4.32Å; F193-F295 AromaticContact CG-CG 3.96Å; F193-F295 HydrophobicContact CG-CG 3.96Å; F193-F295 HydrophobicContact CG-CZ 4.25Å; F193-F295 HydrophobicContact CZ-CD1 4.49Å; F194-F295 HydrophobicContact CE1-CD2 4.32Å; F194-F295 HydrophobicContact CE2-CB 4.4Å; F194-F295 HydrophobicContact CZ-CB 4.07Å; F194-F295 HydrophobicContact CZ-CD2 4.06Å; F273-F295 HydrophobicContact CE2-CE2 4.5Å; E291-F295 WeakPolarHBondContact O-CB 3.31Å; E291-F295 PolarHBondContact O-N 3.18Å; F295-T297 VanDerWaalsContact C-N 3.32Å; F295-T297 PolarHBondContact O-N 2.77Å; F295-I298 PolarHBondContact O-N 3.42Å; F295-A299 HydrophobicContact CE1-CB 4.47Å; F295-A299 WeakPolarHBondContact O-CB 3.2Å; F295-A299 PolarHBondContact O-N 2.78Å
296	T	81	Confident	81.5	Confident	15 Å²	15	45.3 Å²	45.3	9%	0.092	24%	0.237	C	C	.	.	H	α-helix	trans	-60.9	-42.1	178.7	-58.6	0	0	0	0	111.3	L292 L293 F294 A299 W300	L292-T296 VanDerWaalsContact O-CB 3.24Å; L292-T296 WeakPolarHBondContact O-CB 3.19Å; L292-T296 PolarHBondContact O-N 3.42Å; L292-T296 PolarHBondContact O-OG1 3.44Å; L293-T296 PolarHBondContact O-N 2.89Å; F294-T296 PolarHBondContact O-N 2.95Å; T296-A299 PolarHBondContact O-N 2.96Å; T296-W300 PolarHBondContact O-N 2.98Å
297	T	84.7	Confident	82.8	Confident	76 Å²	76	41 Å²	41	47%	0.466	21%	0.212	S	C	.	.	H	α-helix	trans	-64	-43.2	177.4	-57.8	0	0	0	0	111.4	L293 F294 F295 W300 V301	L293-T297 WeakPolarHBondContact O-CB 3.34Å; L293-T297 PolarHBondContact O-N 3.36Å; L293-T297 PolarHBondContact O-OG1 3.41Å; F294-T297 PolarHBondContact O-N 3.27Å; F295-T297 VanDerWaalsContact C-N 3.32Å; F295-T297 PolarHBondContact O-N 2.77Å; T297-W300 WeakPolarHBondContact O-CB 3.24Å; T297-W300 PolarHBondContact O-N 3.29Å; T297-V301 WeakPolarHBondContact O-CG2 3.25Å; T297-V301 PolarHBondContact O-N 2.88Å
298	I	87.3	Confident	83.9	Confident	10 Å²	10	40.6 Å²	40.6	5%	0.051	21%	0.21	C	C	.	.	H	α-helix	trans	-61.1	-47.9	174.8	-70.3	167.5	0	0	0	110.6	P272 F273 A276 F294 F295 W300 V301 C302	P272-I298 HydrophobicContact CB-CG1 4.2Å; P272-I298 HydrophobicContact CB-CG2 4.49Å; F273-I298 HydrophobicContact CB-CG2 3.81Å; F273-I298 HydrophobicContact CD2-CG2 4.12Å; A276-I298 HydrophobicContact CB-CD1 3.52Å; F294-I298 HydrophobicContact CD1-CD1 3.87Å; F294-I298 HydrophobicContact CD2-CD1 4.31Å; F294-I298 HydrophobicContact CE1-CD1 3.46Å; F294-I298 VanDerWaalsContact CE1-CD1 3.46Å; F294-I298 HydrophobicContact CE2-CD1 3.94Å; F294-I298 HydrophobicContact CG-CD1 4.28Å; F294-I298 HydrophobicContact CZ-CD1 3.51Å; F294-I298 WeakPolarHBondContact O-CG1 3.28Å; F294-I298 PolarHBondContact O-N 3.27Å; F295-I298 PolarHBondContact O-N 3.42Å; I298-W300 PolarHBondContact O-N 2.94Å; I298-V301 PolarHBondContact O-N 3.44Å; I298-C302 PolarHBondContact O-N 3.37Å; I298-C302 PolarHBondContact O-SG 3Å
299	A	84.6	Confident	84.7	Confident	7 Å²	7	38.6 Å²	38.6	6%	0.058	20%	0.195	C	C	.	.	H	α-helix	trans	-57.6	-40.2	-179.9	0	0	0	0	0	111.2	F295 T296 C302 F303	F295-A299 HydrophobicContact CE1-CB 4.47Å; F295-A299 WeakPolarHBondContact O-CB 3.2Å; F295-A299 PolarHBondContact O-N 2.78Å; T296-A299 PolarHBondContact O-N 2.96Å; A299-C302 PolarHBondContact O-N 3.39Å; A299-F303 VanDerWaalsContact O-CB 3.3Å; A299-F303 WeakPolarHBondContact O-CB 3.24Å; A299-F303 PolarHBondContact O-N 3.28Å
300	W	84.3	Confident	85.4	Confident	50 Å²	50	35.3 Å²	35.3	19%	0.189	18%	0.184	C	C	.	.	H	α-helix	trans	-65.4	-45.6	176.2	-71.4	9	0	0	0	114.1	L50 V53 F54 T296 T297 I298 C302 F303 S304	L50-W300 VanDerWaalsContact CA-CH2 3.47Å; L50-W300 HydrophobicContact CB-CH2 3.82Å; L50-W300 HydrophobicContact CB-CZ2 3.47Å; L50-W300 VanDerWaalsContact CB-CZ2 3.47Å; L50-W300 HydrophobicContact CD2-CH2 3.01Å; L50-W300 HydrophobicContact CD2-CZ2 3.31Å; L50-W300 HydrophobicContact CD2-CZ3 3.67Å; L50-W300 HydrophobicContact CG-CH2 3.89Å; L50-W300 HydrophobicContact CG-CZ2 3.9Å; L50-W300 WeakPolarHBondContact O-CZ2 3.36Å; V53-W300 HydrophobicContact CB-CH2 4.06Å; V53-W300 HydrophobicContact CG1-CH2 4.24Å; V53-W300 HydrophobicContact CG1-CZ3 4.26Å; F54-W300 HydrophobicContact CB-CZ2 4.43Å; F54-W300 AromaticContact CD2-CD1 3.53Å; F54-W300 AromaticContact CD2-NE1 3.64Å; T296-W300 PolarHBondContact O-N 2.98Å; T297-W300 WeakPolarHBondContact O-CB 3.24Å; T297-W300 PolarHBondContact O-N 3.29Å; I298-W300 PolarHBondContact O-N 2.94Å; W300-C302 VanDerWaalsContact C-N 3.28Å; W300-C302 PolarHBondContact O-N 2.87Å; W300-F303 PolarHBondContact O-N 2.71Å; W300-F303 VanDerWaalsContact O-N 3.16Å; W300-S304 WeakPolarHBondContact O-CB 3.37Å; W300-S304 PolarHBondContact O-N 3.41Å
301	V	88.9	Confident	85.9	Confident	57 Å²	57	30.8 Å²	30.8	35%	0.345	17%	0.171	S	C	.	.	H	α-helix	trans	-59.2	-45.4	176.7	171.1	0	0	0	0	109.3	T269 T297 I298 F303 S304	T269-V301 HydrophobicContact CG2-CG1 3.95Å; T297-V301 WeakPolarHBondContact O-CG2 3.25Å; T297-V301 PolarHBondContact O-N 2.88Å; I298-V301 PolarHBondContact O-N 3.44Å; V301-F303 PolarHBondContact O-N 3.42Å; V301-S304 PolarHBondContact O-N 2.95Å; V301-S304 PolarHBondContact O-OG 2.82Å
302	C	88.8	Confident	86.3	Confident	2 Å²	2	30 Å²	30	1%	0.014	17%	0.168	C	C	.	.	H	α-helix	trans	-59.5	-46.3	174.8	-62.7	0	0	0	0	111.5	T269 W270 I298 A299 W300 S304 S305	T269-C302 PolarHBondContact O-SG 3.01Å; T269-C302 VanDerWaalsContact O-SG 3.41Å; W270-C302 HydrophobicContact CD2-CB 4.16Å; W270-C302 HydrophobicContact CE3-CB 4.33Å; W270-C302 HydrophobicContact CH2-CB 4.1Å; W270-C302 HydrophobicContact CZ2-CB 3.9Å; W270-C302 HydrophobicContact CZ3-CB 4.3Å; I298-C302 PolarHBondContact O-N 3.37Å; I298-C302 PolarHBondContact O-SG 3Å; A299-C302 PolarHBondContact O-N 3.39Å; W300-C302 VanDerWaalsContact C-N 3.28Å; W300-C302 PolarHBondContact O-N 2.87Å; C302-S304 VanDerWaalsContact C-N 3.34Å; C302-S304 PolarHBondContact O-N 2.69Å; C302-S305 WeakPolarHBondContact O-CB 3.15Å; C302-S305 PolarHBondContact O-N 3.16Å; C302-S305 PolarHBondContact O-OG 3.06Å
303	F	85.8	Confident	86.8	Confident	2 Å²	2	28.9 Å²	28.9	1%	0.009	16%	0.163	C	C	.	.	H	α-helix	trans	-68.7	-31.8	-176.4	-152.1	-83.5	0	0	0	113.2	F54 L57 W58 S61 S97 A101 A299 W300 V301 S305 T306 A307	F54-F303 HydrophobicContact CE2-CB 4.37Å; F54-F303 HydrophobicContact CE2-CD2 4.25Å; F54-F303 HydrophobicContact CE2-CG 4.15Å; F54-F303 HydrophobicContact CZ-CD2 4.46Å; L57-F303 HydrophobicContact CB-CD1 4Å; L57-F303 HydrophobicContact CB-CE1 4.48Å; W58-F303 VanDerWaalsContact CA-CE1 3.42Å; W58-F303 HydrophobicContact CB-CE1 4.16Å; W58-F303 HydrophobicContact CB-CZ 4.3Å; W58-F303 AromaticContact CD1-CZ 3.74Å; W58-F303 HydrophobicContact CG-CZ 4.39Å; S61-F303 VanDerWaalsContact CB-CE1 3.48Å; S97-F303 WeakPolarHBondContact OG-CZ 3.33Å; A101-F303 HydrophobicContact CB-CD2 4.09Å; A101-F303 HydrophobicContact CB-CE2 3.55Å; A299-F303 VanDerWaalsContact O-CB 3.3Å; A299-F303 WeakPolarHBondContact O-CB 3.24Å; A299-F303 PolarHBondContact O-N 3.28Å; W300-F303 PolarHBondContact O-N 2.71Å; W300-F303 VanDerWaalsContact O-N 3.16Å; V301-F303 PolarHBondContact O-N 3.42Å; F303-S305 PolarHBondContact O-N 3.06Å; F303-T306 VanDerWaalsContact O-CB 3.28Å; F303-T306 WeakPolarHBondContact O-CB 3.37Å; F303-T306 PolarHBondContact O-N 3.36Å; F303-T306 VanDerWaalsContact O-N 3.13Å; F303-A307 PolarHBondContact O-N 2.98Å; F303-A307 VanDerWaalsContact O-N 3.16Å
304	S	88.1	Confident	87	Confident	37 Å²	37	28.1 Å²	28.1	26%	0.259	16%	0.162	S	C	.	.	H	α-helix	trans	-59.2	-33.1	174.3	78.2	0	0	0	0	112.4	W300 V301 C302 T306 A307 S308	W300-S304 WeakPolarHBondContact O-CB 3.37Å; W300-S304 PolarHBondContact O-N 3.41Å; V301-S304 PolarHBondContact O-N 2.95Å; V301-S304 PolarHBondContact O-OG 2.82Å; C302-S304 VanDerWaalsContact C-N 3.34Å; C302-S304 PolarHBondContact O-N 2.69Å; S304-T306 VanDerWaalsContact C-N 3.35Å; S304-A307 PolarHBondContact O-N 3.06Å; S304-S308 WeakPolarHBondContact O-CB 3.45Å; S304-S308 PolarHBondContact O-N 3.33Å; S304-S308 VanDerWaalsContact O-N 3.07Å; S304-S308 PolarHBondContact O-OG 3.07Å
305	S	89	Confident	87.1	Confident	2 Å²	2	26.5 Å²	26.5	1%	0.014	16%	0.16	C	C	.	.	H	α-helix	trans	-64.8	-40.6	177.2	80.9	0	0	0	0	111.7	T269 W270 C302 F303 S308	T269-S305 WeakPolarHBondContact OG1-CB 2.85Å; W270-S305 PolarHBondContact NE1-OG 3.37Å; C302-S305 WeakPolarHBondContact O-CB 3.15Å; C302-S305 PolarHBondContact O-N 3.16Å; C302-S305 PolarHBondContact O-OG 3.06Å; F303-S305 PolarHBondContact O-N 3.06Å; S305-S308 PolarHBondContact O-N 3.26Å
306	T	90.7	Very high	86.9	Confident	1 Å²	1	28.6 Å²	28.6	1%	0.006	17%	0.168	C	C	.	.	H	α-helix	trans	-63	-47.8	176.9	-48.8	0	0	0	0	111.4	S61 N65 D93 M96 F303 S304 S308 K309	S61-T306 WeakPolarHBondContact OG-CG2 3.36Å; N65-T306 PolarHBondContact ND2-O 3.43Å; D93-T306 HydrophobicContact CB-CG2 3.45Å; D93-T306 VanDerWaalsContact CB-CG2 3.45Å; D93-T306 WeakPolarHBondContact OD1-CG2 3.18Å; M96-T306 HydrophobicContact CE-CG2 3.87Å; M96-T306 WeakPolarHBondContact CE-OG1 3.27Å; F303-T306 VanDerWaalsContact O-CB 3.28Å; F303-T306 WeakPolarHBondContact O-CB 3.37Å; F303-T306 PolarHBondContact O-N 3.36Å; F303-T306 VanDerWaalsContact O-N 3.13Å; S304-T306 VanDerWaalsContact C-N 3.35Å; T306-S308 VanDerWaalsContact C-N 3.26Å; T306-S308 PolarHBondContact O-N 3.43Å; T306-K309 PolarHBondContact O-N 3.04Å
307	A	89.8	Confident	86.8	Confident	7 Å²	7	28.2 Å²	28.2	6%	0.058	17%	0.166	C	C	.	.	H	α-helix	trans	-66.3	-26.5	178.9	0	0	0	0	0	113.1	L57 V60 F303 S304 P310	L57-A307 HydrophobicContact CD2-CB 4.22Å; V60-A307 HydrophobicContact CB-CB 4.35Å; V60-A307 HydrophobicContact CG1-CB 4.02Å; F303-A307 PolarHBondContact O-N 2.98Å; F303-A307 VanDerWaalsContact O-N 3.16Å; S304-A307 PolarHBondContact O-N 3.06Å; A307-P310 WeakPolarHBondContact O-CD 3.09Å
308	S	90.2	Very high	86.5	Confident	47 Å²	47	26.5 Å²	26.5	33%	0.329	16%	0.159	S	C	.	.	H	α-helix	trans	-76.6	-28.9	-177.2	-63	0	0	0	0	113.4	S304 S305 T306 T311 L312	S304-S308 WeakPolarHBondContact O-CB 3.45Å; S304-S308 PolarHBondContact O-N 3.33Å; S304-S308 VanDerWaalsContact O-N 3.07Å; S304-S308 PolarHBondContact O-OG 3.07Å; S305-S308 PolarHBondContact O-N 3.26Å; T306-S308 VanDerWaalsContact C-N 3.26Å; T306-S308 PolarHBondContact O-N 3.43Å; S308-T311 WeakPolarHBondContact O-CB 3.28Å; S308-T311 PolarHBondContact O-N 2.88Å; S308-L312 WeakPolarHBondContact O-CG 3.48Å; S308-L312 PolarHBondContact O-N 3.45Å; S308-L312 VanDerWaalsContact O-N 3.09Å
309	K	89.5	Confident	86.1	Confident	11 Å²	11	29 Å²	29	5%	0.048	17%	0.173	C	C	.	.	H	α-helix	trans	-59.2	-45.7	-171.3	-69.2	167.6	179	-176.3	0	115	D93 L262 T306 T311 L312 Y313	D93-K309 IonicContact OD1-NZ 3.91Å; D93-K309 PolarHBondContact OD1-NZ 3.08Å; D93-K309 WeakPolarHBondContact OD2-CD 3.46Å; D93-K309 IonicContact OD2-NZ 2.74Å; D93-K309 PolarHBondContact OD2-NZ 3Å; L262-K309 HydrophobicContact CD2-CB 4.39Å; L262-K309 HydrophobicContact CD2-CG 3.91Å; T306-K309 PolarHBondContact O-N 3.04Å; K309-T311 PolarHBondContact O-N 3.19Å; K309-L312 PolarHBondContact O-N 3.11Å; K309-Y313 HydrophobicContact CB-CE2 3.87Å; K309-Y313 WeakPolarHBondContact O-CD2 3.34Å; K309-Y313 PolarHBondContact O-N 3.34Å
310	P	89.8	Confident	86	Confident	15 Å²	15	28.9 Å²	28.9	10%	0.097	17%	0.171	C	C	.	.	H	α-helix	trans	-55.5	-39.4	177.1	-26.5	36.9	0	0	0	112.6	V68 A307 Y313 S314	V68-P310 HydrophobicContact CG2-CB 4.13Å; V68-P310 HydrophobicContact CG2-CG 4.33Å; A307-P310 WeakPolarHBondContact O-CD 3.09Å; P310-Y313 PolarHBondContact O-N 3.22Å; P310-S314 PolarHBondContact O-N 3.1Å
311	T	88.4	Confident	86	Confident	81 Å²	81	31.7 Å²	31.7	50%	0.497	18%	0.181	S	C	.	.	H	α-helix	trans	-66	-41.7	174.6	-54.3	0	0	0	0	111.7	S308 K309 Y313 S314 V315	S308-T311 WeakPolarHBondContact O-CB 3.28Å; S308-T311 PolarHBondContact O-N 2.88Å; K309-T311 PolarHBondContact O-N 3.19Å; T311-Y313 VanDerWaalsContact C-N 3.32Å; T311-Y313 PolarHBondContact O-N 3.38Å; T311-S314 PolarHBondContact O-N 3.41Å; T311-S314 PolarHBondContact O-OG 3.44Å; T311-V315 WeakPolarHBondContact O-CG2 3.41Å; T311-V315 PolarHBondContact O-N 2.98Å
312	L	87.3	Confident	85.7	Confident	28 Å²	28	34.8 Å²	34.8	15%	0.147	19%	0.187	C	C	.	.	H	α-helix	trans	-64.4	-38.5	176	-56.8	175.3	0	0	0	111.4	M261 L262 S308 K309 V315 Y316	M261-L312 HydrophobicContact CE-CB 3.89Å; M261-L312 HydrophobicContact CE-CD1 4.1Å; M261-L312 HydrophobicContact CE-CD2 3.2Å; M261-L312 HydrophobicContact CE-CG 3.86Å; M261-L312 HydrophobicContact SD-CD2 3.78Å; L262-L312 HydrophobicContact CD2-CB 4.01Å; L262-L312 HydrophobicContact CD2-CD1 3.5Å; L262-L312 HydrophobicContact CD2-CG 4.39Å; L262-L312 HydrophobicContact CG-CD1 4.17Å; S308-L312 WeakPolarHBondContact O-CG 3.48Å; S308-L312 PolarHBondContact O-N 3.45Å; S308-L312 VanDerWaalsContact O-N 3.09Å; K309-L312 PolarHBondContact O-N 3.11Å; L312-V315 PolarHBondContact O-N 2.92Å; L312-Y316 WeakPolarHBondContact O-CB 3.47Å; L312-Y316 WeakPolarHBondContact O-CD2 3.5Å; L312-Y316 PolarHBondContact O-N 3.48Å
313	Y	87.8	Confident	85.5	Confident	0 Å²	0	34.7 Å²	34.7	0%	0	19%	0.186	C	C	.	.	H	α-helix	trans	-66.1	-40.3	173	-59.1	-42.8	0	0	0	112	V68 V86 M89 M258 L262 K309 P310 T311 V315 N317	V68-Y313 HydrophobicContact CG1-CD2 4.31Å; V68-Y313 HydrophobicContact CG1-CE2 4.44Å; V68-Y313 HydrophobicContact CG2-CD2 3.84Å; V68-Y313 HydrophobicContact CG2-CE2 4.44Å; V86-Y313 HydrophobicContact CG1-CD1 4.28Å; V86-Y313 HydrophobicContact CG1-CD2 3.98Å; V86-Y313 HydrophobicContact CG1-CE1 4.02Å; V86-Y313 HydrophobicContact CG1-CE2 3.73Å; V86-Y313 HydrophobicContact CG1-CG 4.28Å; V86-Y313 HydrophobicContact CG2-CD1 4.4Å; V86-Y313 HydrophobicContact CG2-CE1 3.91Å; M89-Y313 WeakPolarHBondContact CE-OH 3.44Å; M258-Y313 HydrophobicContact CE-CD1 4.45Å; M258-Y313 HydrophobicContact SD-CD1 4.15Å; L262-Y313 HydrophobicContact CD1-CD1 4.28Å; L262-Y313 HydrophobicContact CD1-CE1 3.56Å; L262-Y313 HydrophobicContact CD2-CE1 4.24Å; K309-Y313 HydrophobicContact CB-CE2 3.87Å; K309-Y313 WeakPolarHBondContact O-CD2 3.34Å; K309-Y313 PolarHBondContact O-N 3.34Å; P310-Y313 PolarHBondContact O-N 3.22Å; T311-Y313 VanDerWaalsContact C-N 3.32Å; T311-Y313 PolarHBondContact O-N 3.38Å; Y313-V315 VanDerWaalsContact C-N 3.34Å; Y313-V315 PolarHBondContact O-N 2.91Å; Y313-N317 WeakPolarHBondContact O-CA 3.39Å; Y313-N317 WeakPolarHBondContact O-CB 3.4Å; Y313-N317 PolarHBondContact O-N 3.48Å
314	S	85.4	Confident	85.5	Confident	36 Å²	36	36.5 Å²	36.5	25%	0.252	20%	0.195	S	C	.	.	H	α-helix	trans	-62.9	-39.4	177.9	80.1	0	0	0	0	111.9	P310 T311 R321	P310-S314 PolarHBondContact O-N 3.1Å; T311-S314 PolarHBondContact O-N 3.41Å; T311-S314 PolarHBondContact O-OG 3.44Å; S314-R321 WeakPolarHBondContact O-CD 3.26Å; S314-R321 WeakPolarHBondContact O-CG 3.27Å
315	V	83.9	Confident	85.3	Confident	69 Å²	69	43.6 Å²	43.6	42%	0.418	22%	0.216	S	C	.	.	H	α-helix	trans	-74.3	-43.7	179.7	176	0	0	0	0	111.6	K254 T311 L312 Y313 R321	K254-V315 WeakPolarHBondContact CE-O 3.29Å; K254-V315 PolarHBondContact NZ-O 2.99Å; T311-V315 WeakPolarHBondContact O-CG2 3.41Å; T311-V315 PolarHBondContact O-N 2.98Å; L312-V315 PolarHBondContact O-N 2.92Å; Y313-V315 VanDerWaalsContact C-N 3.34Å; Y313-V315 PolarHBondContact O-N 2.91Å; V315-R321 PolarHBondContact O-NH1 3.27Å
316	Y	78.8	Confident	85	Confident	47 Å²	47	45.3 Å²	45.3	18%	0.184	22%	0.224	C	C	.	.	H	α-helix	trans	-107.2	-27	-165.2	-69.7	-85.3	0	0	0	115.8	K254 K257 M258 M261 L312 A318	K254-Y316 HydrophobicContact CG-CD1 3.95Å; K257-Y316 HydrophobicContact CD-CE1 4.17Å; K257-Y316 HydrophobicContact CG-CE1 4.38Å; M258-Y316 HydrophobicContact CB-CD1 4.42Å; M258-Y316 HydrophobicContact CB-CG 4.03Å; M258-Y316 VanDerWaalsContact CG-CB 3.44Å; M258-Y316 HydrophobicContact CG-CG 4.18Å; M261-Y316 HydrophobicContact CE-CD2 3.39Å; M261-Y316 HydrophobicContact CE-CE2 3.16Å; M261-Y316 HydrophobicContact CE-CG 4.37Å; M261-Y316 HydrophobicContact SD-CE2 3.79Å; L312-Y316 WeakPolarHBondContact O-CB 3.47Å; L312-Y316 WeakPolarHBondContact O-CD2 3.5Å; L312-Y316 PolarHBondContact O-N 3.48Å; Y316-A318 PolarHBondContact O-N 3.42Å
317	N	79.6	Confident	84.7	Confident	8 Å²	8	45.7 Å²	45.7	4%	0.043	23%	0.227	C	C	.	.			trans	-91.3	100	-179.2	-171	-20.7	0	0	0	110.8	M258 Y313 N319 F320 R321	M258-N317 HydrophobicContact SD-CB 3.79Å; Y313-N317 WeakPolarHBondContact O-CA 3.39Å; Y313-N317 WeakPolarHBondContact O-CB 3.4Å; Y313-N317 PolarHBondContact O-N 3.48Å; N317-N319 VanDerWaalsContact C-N 3.26Å; N317-N319 PolarHBondContact O-N 3.37Å; N317-N319 WeakPolarHBondContact OD1-CB 3.34Å; N317-N319 PolarHBondContact OD1-N 2.89Å; N317-F320 HydrophobicContact CB-CB 3.77Å; N317-F320 WeakPolarHBondContact O-CB 3.5Å; N317-F320 PolarHBondContact O-N 2.88Å; N317-F320 VanDerWaalsContact O-N 3.16Å; N317-F320 PolarHBondContact OD1-N 2.82Å; N317-F320 VanDerWaalsContact OD1-N 3.12Å; N317-R321 PolarHBondContact O-N 3.25Å
318	A	78.6	Confident	84.4	Confident	40 Å²	40	51.1 Å²	51.1	33%	0.331	25%	0.249	S	C	.	.	H	α-helix	trans	-61.4	-33.5	179.4	0	0	0	0	0	113.1	Y316 R322	Y316-A318 PolarHBondContact O-N 3.42Å; A318-R322 PolarHBondContact O-N 2.94Å; A318-R322 VanDerWaalsContact O-N 3.08Å
319	N	78.2	Confident	83.7	Confident	63 Å²	63	52.2 Å²	52.2	34%	0.337	26%	0.256	S	S	.	.	H	α-helix	trans	-66.2	-44.5	175.9	-63.8	-26.7	0	0	0	110.1	T78 N317 R321 R322 G323	T78-N319 HydrophobicContact CG2-CB 4.07Å; T78-N319 WeakPolarHBondContact CG2-O 3.39Å; N317-N319 VanDerWaalsContact C-N 3.26Å; N317-N319 PolarHBondContact O-N 3.37Å; N317-N319 WeakPolarHBondContact OD1-CB 3.34Å; N317-N319 PolarHBondContact OD1-N 2.89Å; N319-R321 PolarHBondContact O-N 2.81Å; N319-R322 PolarHBondContact O-N 3.04Å; N319-G323 PolarHBondContact O-N 2.94Å
320	F	82.4	Confident	82.3	Confident	3 Å²	3	57 Å²	57	1%	0.013	28%	0.28	C	S	.	.	H	α-helix	trans	-60.5	-46.5	177.1	-178.7	-113.2	0	0	0	112	V68 V71 N317 R322 G323 M324	V68-F320 HydrophobicContact CB-CE2 4.31Å; V68-F320 HydrophobicContact CG2-CE2 3.9Å; V68-F320 HydrophobicContact CG2-CZ 3.84Å; V71-F320 HydrophobicContact CB-CD2 4.12Å; V71-F320 HydrophobicContact CB-CE2 3.74Å; V71-F320 HydrophobicContact CG1-CD2 3.63Å; V71-F320 HydrophobicContact CG1-CE2 3.73Å; V71-F320 HydrophobicContact CG2-CE2 4.02Å; N317-F320 HydrophobicContact CB-CB 3.77Å; N317-F320 WeakPolarHBondContact O-CB 3.5Å; N317-F320 PolarHBondContact O-N 2.88Å; N317-F320 VanDerWaalsContact O-N 3.16Å; N317-F320 PolarHBondContact OD1-N 2.82Å; N317-F320 VanDerWaalsContact OD1-N 3.12Å; F320-R322 VanDerWaalsContact C-N 3.31Å; F320-R322 PolarHBondContact O-N 3.31Å; F320-G323 PolarHBondContact O-N 2.81Å; F320-G323 VanDerWaalsContact O-N 3.17Å; F320-M324 HydrophobicContact CD1-CE 3.97Å; F320-M324 HydrophobicContact CD1-CG 4.42Å; F320-M324 HydrophobicContact CD1-SD 4.2Å; F320-M324 HydrophobicContact CE1-CE 3.74Å; F320-M324 HydrophobicContact CE1-CG 4.01Å; F320-M324 HydrophobicContact CE1-SD 3.47Å; F320-M324 WeakPolarHBondContact CE1-SD 3.46Å; F320-M324 HydrophobicContact CE2-CG 4.11Å; F320-M324 HydrophobicContact CZ-CE 4.48Å; F320-M324 HydrophobicContact CZ-CG 3.84Å; F320-M324 HydrophobicContact CZ-SD 3.66Å; F320-M324 PolarHBondContact O-N 2.84Å
321	R	85.3	Confident	80.6	Confident	109 Å²	109	60.2 Å²	60.2	41%	0.411	30%	0.303	S	S	.	.	H	α-helix	trans	-58	-41.2	174.9	-70.2	-168.5	-63	-151	20.1	113.5	S314 V315 N317 N319 M324 R325	S314-R321 WeakPolarHBondContact O-CD 3.26Å; S314-R321 WeakPolarHBondContact O-CG 3.27Å; V315-R321 PolarHBondContact O-NH1 3.27Å; N317-R321 PolarHBondContact O-N 3.25Å; N319-R321 PolarHBondContact O-N 2.81Å; R321-M324 HydrophobicContact CG-CE 4.24Å; R321-M324 PolarHBondContact O-N 2.99Å; R321-R325 PolarHBondContact O-N 2.83Å
322	R	82.8	Confident	78.6	Confident	122 Å²	122	61 Å²	61	46%	0.46	31%	0.311	S	S	.	.	H	α-helix	trans	-63.6	-46.4	176.7	-176.9	-176.6	177.7	156.7	13.8	110.6	A318 N319 F320 M324 R325 E326	A318-R322 PolarHBondContact O-N 2.94Å; A318-R322 VanDerWaalsContact O-N 3.08Å; N319-R322 PolarHBondContact O-N 3.04Å; F320-R322 VanDerWaalsContact C-N 3.31Å; F320-R322 PolarHBondContact O-N 3.31Å; R322-M324 VanDerWaalsContact C-N 3.33Å; R322-M324 PolarHBondContact O-N 3.07Å; R322-R325 PolarHBondContact O-N 2.9Å; R322-E326 IonicContact CZ-OE1 2.8Å; R322-E326 IonicContact NE-OE1 2.88Å; R322-E326 PolarHBondContact NE-OE1 3.26Å; R322-E326 WeakPolarHBondContact O-CG 3.33Å; R322-E326 PolarHBondContact O-N 3.39Å
323	G	83.7	Confident	76.5	Confident	0 Å²	0	70.6 Å²	70.6	0%	0	36%	0.358	C	S	.	.	H	α-helix	trans	-62.9	-37.8	177.4	0	0	0	0	0	112.9	V71 N319 F320 E326 T327	V71-G323 VanDerWaalsContact CG1-C 3.41Å; N319-G323 PolarHBondContact O-N 2.94Å; F320-G323 PolarHBondContact O-N 2.81Å; F320-G323 VanDerWaalsContact O-N 3.17Å; G323-E326 PolarHBondContact O-N 3.46Å; G323-T327 WeakPolarHBondContact O-CB 3.45Å; G323-T327 PolarHBondContact O-N 3.42Å; G323-T327 PolarHBondContact O-OG1 3.18Å
324	M	85.9	Confident	75.9	Confident	41 Å²	41	74.2 Å²	74.2	20%	0.202	38%	0.376	C	S	.	.	H	α-helix	trans	-60	-48.8	172.1	-75	-164.7	-61	0	0	110.8	L67 V71 F320 R321 R322 E326 T327 F328	L67-M324 HydrophobicContact CD2-SD 4.46Å; V71-M324 HydrophobicContact CG1-CG 4.29Å; V71-M324 HydrophobicContact CG2-CG 3.85Å; F320-M324 HydrophobicContact CD1-CE 3.97Å; F320-M324 HydrophobicContact CD1-CG 4.42Å; F320-M324 HydrophobicContact CD1-SD 4.2Å; F320-M324 HydrophobicContact CE1-CE 3.74Å; F320-M324 HydrophobicContact CE1-CG 4.01Å; F320-M324 HydrophobicContact CE1-SD 3.47Å; F320-M324 WeakPolarHBondContact CE1-SD 3.46Å; F320-M324 HydrophobicContact CE2-CG 4.11Å; F320-M324 HydrophobicContact CZ-CE 4.48Å; F320-M324 HydrophobicContact CZ-CG 3.84Å; F320-M324 HydrophobicContact CZ-SD 3.66Å; F320-M324 PolarHBondContact O-N 2.84Å; R321-M324 HydrophobicContact CG-CE 4.24Å; R321-M324 PolarHBondContact O-N 2.99Å; R322-M324 VanDerWaalsContact C-N 3.33Å; R322-M324 PolarHBondContact O-N 3.07Å; M324-E326 VanDerWaalsContact C-N 3.33Å; M324-E326 PolarHBondContact O-N 3.35Å; M324-T327 PolarHBondContact O-N 3.24Å; M324-T327 VanDerWaalsContact O-N 3.16Å; M324-F328 HydrophobicContact CB-CD2 4.3Å; M324-F328 HydrophobicContact CB-CE2 4.47Å; M324-F328 WeakPolarHBondContact O-CD2 3.35Å; M324-F328 PolarHBondContact O-N 3.02Å
325	R	85.1	Confident	75.4	Confident	185 Å²	185	76.2 Å²	76.2	70%	0.698	38%	0.383	S	S	*	.	H	α-helix	trans	-59.1	-43.3	176.9	-170.3	-178	-71.1	-126.6	-2	111.7	R321 R322 T327 C329	R321-R325 PolarHBondContact O-N 2.83Å; R322-R325 PolarHBondContact O-N 2.9Å; R325-T327 VanDerWaalsContact C-N 3.34Å; R325-T327 PolarHBondContact O-N 2.7Å; R325-C329 HydrophobicContact CG-CB 4.29Å; R325-C329 WeakPolarHBondContact O-CA 3.31Å; R325-C329 WeakPolarHBondContact O-CB 3.24Å; R325-C329 PolarHBondContact O-N 2.96Å; R325-C329 PolarHBondContact O-SG 3Å; R325-C329 VanDerWaalsContact O-SG 3.37Å
326	E	83	Confident	74.9	Confident	38 Å²	38	76.6 Å²	76.6	18%	0.178	38%	0.381	C	S	.	.	H	α-helix	trans	-64.2	-38.5	176.8	-71.2	171.7	-177.1	0	0	112.1	S75 R322 G323 M324 M330	S75-E326 WeakPolarHBondContact CB-OE2 3.28Å; S75-E326 PolarHBondContact OG-OE2 2.93Å; R322-E326 IonicContact CZ-OE1 2.8Å; R322-E326 IonicContact NE-OE1 2.88Å; R322-E326 PolarHBondContact NE-OE1 3.26Å; R322-E326 WeakPolarHBondContact O-CG 3.33Å; R322-E326 PolarHBondContact O-N 3.39Å; G323-E326 PolarHBondContact O-N 3.46Å; M324-E326 VanDerWaalsContact C-N 3.33Å; M324-E326 PolarHBondContact O-N 3.35Å; E326-M330 WeakPolarHBondContact O-CB 3.42Å; E326-M330 WeakPolarHBondContact O-CG 3.15Å; E326-M330 PolarHBondContact O-N 3.44Å
327	T	84.1	Confident	74.7	Confident	9 Å²	9	78.3 Å²	78.3	6%	0.055	39%	0.393	C	S	.	.	H	α-helix	trans	-70.5	-46.9	-179.9	-55.8	0	0	0	0	111.7	L70 G323 M324 R325 S331	L70-T327 HydrophobicContact CD2-CG2 3.53Å; G323-T327 WeakPolarHBondContact O-CB 3.45Å; G323-T327 PolarHBondContact O-N 3.42Å; G323-T327 PolarHBondContact O-OG1 3.18Å; M324-T327 PolarHBondContact O-N 3.24Å; M324-T327 VanDerWaalsContact O-N 3.16Å; R325-T327 VanDerWaalsContact C-N 3.34Å; R325-T327 PolarHBondContact O-N 2.7Å; T327-S331 PolarHBondContact O-OG 2.96Å
328	F	83.6	Confident	74.4	Confident	121 Å²	121	82.7 Å²	82.7	53%	0.531	41%	0.414	S	S	.	.	H	α-helix	trans	-86.2	-33.3	-174.9	-66.8	-67.9	0	0	0	113.6	L67 M324	L67-F328 HydrophobicContact CD1-CE2 3.84Å; L67-F328 HydrophobicContact CD1-CZ 3.59Å; L67-F328 HydrophobicContact CD2-CE2 4.25Å; L67-F328 HydrophobicContact CD2-CZ 4.24Å; M324-F328 HydrophobicContact CB-CD2 4.3Å; M324-F328 HydrophobicContact CB-CE2 4.47Å; M324-F328 WeakPolarHBondContact O-CD2 3.35Å; M324-F328 PolarHBondContact O-N 3.02Å
329	C	75.4	Confident	74.1	Confident	70 Å²	70	85.5 Å²	85.5	47%	0.473	42%	0.42	S	S	.	.	H	α-helix	trans	-88.2	-20.7	-179.6	-55.2	0	0	0	0	114	R325 S331 S332	R325-C329 HydrophobicContact CG-CB 4.29Å; R325-C329 WeakPolarHBondContact O-CA 3.31Å; R325-C329 WeakPolarHBondContact O-CB 3.24Å; R325-C329 PolarHBondContact O-N 2.96Å; R325-C329 PolarHBondContact O-SG 3Å; R325-C329 VanDerWaalsContact O-SG 3.37Å; C329-S331 VanDerWaalsContact C-N 3.34Å; C329-S332 PolarHBondContact O-OG 3.06Å
330	M	59.8	Low	73.8	Confident	112 Å²	112	87.1 Å²	87.1	55%	0.552	43%	0.426	S	S	*	.	S	Bend	trans	-85.7	-9.3	169.2	-59	-172.2	-19.5	0	0	112.8	E326	E326-M330 WeakPolarHBondContact O-CB 3.42Å; E326-M330 WeakPolarHBondContact O-CG 3.15Å; E326-M330 PolarHBondContact O-N 3.44Å
331	S	53.5	Low	73.2	Confident	83 Å²	83	93.6 Å²	93.6	58%	0.58	46%	0.458	S	S	*	.	T	Hydrogen-bonded Turn	trans	-82.8	-3.2	170.1	-56.3	0	0	0	0	112	T327 C329	T327-S331 PolarHBondContact O-OG 2.96Å; C329-S331 VanDerWaalsContact C-N 3.34Å
332	S	47.5	Very low	72.2	Confident	96 Å²	96	92.3 Å²	92.3	67%	0.671	46%	0.462	S	S	*	.	T	Hydrogen-bonded Turn	trans	-112.7	18.3	178.5	81.1	0	0	0	0	113.7	C329	C329-S332 PolarHBondContact O-OG 3.06Å
333	M	41.9	Very low	71.2	Confident	231 Å²	231	89.6 Å²	89.6	100%	1.138	46%	0.462	S	S	*	.			trans	-126.1	0	170.8	-86.8	-179.1	144.6	0	0	108.3

Retrieved 333 of 333 residues in 62.1 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).