A0A087YS31_POEFO Loading...

Somatostatin receptor type 2

Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

AlphaFold DB , UniProt , Accession A0A087YS31, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 370 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	36.5	Very low	28.9	Very low	246 Å²	246	160.4 Å²	160.4	100%	1.212	85%	0.846	S	S	*	*				0	85.9	0	-82.8	174.2	174.3	0	0	106.6
2	E	29.8	Very low	28.7	Very low	179 Å²	179	158.5 Å²	158.5	84%	0.836	84%	0.837	S	S	*	*			trans	-102.1	131.3	173.2	-73.4	179.3	134.7	0	0	107.6
3	P	31.1	Very low	28.8	Very low	120 Å²	120	157.8 Å²	157.8	78%	0.779	83%	0.833	S	S	*	*			trans	-78.7	128.3	173.8	28.9	-26.7	0	0	0	109.6	M5	P3-M5 PolarHBondContact O-N 2.93Å
4	W	28.6	Very low	29.1	Very low	237 Å²	237	152.2 Å²	152.2	90%	0.898	81%	0.808	S	S	*	*			trans	-57.7	111.7	178.5	-66	81.2	0	0	0	111.4	F6	W4-F6 PolarHBondContact O-N 3.15Å
5	M	24.9	Very low	29.3	Very low	185 Å²	185	149.5 Å²	149.5	91%	0.911	79%	0.789	S	S	*	*	P	Polyproline II helix	trans	-71.7	116.9	161.4	-81.9	-175.4	-87.1	0	0	108.8	P3	P3-M5 PolarHBondContact O-N 2.93Å
6	F	27.4	Very low	29.6	Very low	190 Å²	190	145.3 Å²	145.3	83%	0.833	76%	0.764	S	S	*	*	P	Polyproline II helix	trans	-74.4	134.4	162.8	-75.7	-82.7	0	0	0	109.1	W4 S8	W4-F6 PolarHBondContact O-N 3.15Å; F6-S8 PolarHBondContact O-N 3.25Å
7	P	27.5	Very low	30.2	Very low	110 Å²	110	141.4 Å²	141.4	71%	0.714	74%	0.743	S	S	*	*	P	Polyproline II helix	trans	-70.3	124	178	27.3	-30	0	0	0	109.8	S9	P7-S9 PolarHBondContact O-N 3.48Å
8	S	30.1	Very low	30.6	Very low	119 Å²	119	134.7 Å²	134.7	83%	0.832	71%	0.708	S	S	*	*			trans	-60	97.7	167.1	49.7	0	0	0	0	109.6	F6	F6-S8 PolarHBondContact O-N 3.25Å
9	S	26.5	Very low	31.1	Very low	92 Å²	92	131.6 Å²	131.6	64%	0.643	69%	0.686	S	S	*	*			trans	-79.1	129.4	165.4	-54.2	0	0	0	0	107.7	P7 L11	P7-S9 PolarHBondContact O-N 3.48Å; S9-L11 PolarHBondContact O-N 2.89Å
10	P	28.3	Very low	31.5	Very low	119 Å²	119	127.1 Å²	127.1	77%	0.773	66%	0.663	S	S	*	*			trans	-70.1	103.6	168.9	28.2	-28.1	0	0	0	106.9	N12	P10-N12 PolarHBondContact O-N 3.18Å
11	L	27.7	Very low	32	Very low	167 Å²	167	121.6 Å²	121.6	87%	0.874	64%	0.635	S	S	*	*			trans	-64.6	110.8	171.5	-102.7	117.3	0	0	0	107.8	S9 L13	S9-L11 PolarHBondContact O-N 2.89Å; L11-L13 PolarHBondContact O-N 3.15Å
12	N	26.6	Very low	32.4	Very low	138 Å²	138	110.9 Å²	110.9	74%	0.738	58%	0.582	S	S	*	*			trans	-46.2	102.8	175.9	-95.1	-17.7	0	0	0	111.6	P10 T14	P10-N12 PolarHBondContact O-N 3.18Å; N12-T14 VanDerWaalsContact CB-OG1 3.3Å; N12-T14 WeakPolarHBondContact CB-OG1 3.39Å; N12-T14 PolarHBondContact O-N 3.16Å
13	L	29.7	Very low	32.7	Very low	149 Å²	149	105.8 Å²	105.8	78%	0.78	56%	0.559	S	S	*	*	T	Hydrogen-bonded Turn	trans	-73.2	51.7	170.6	-161.6	81.8	0	0	0	110.2	L11	L11-L13 PolarHBondContact O-N 3.15Å
14	T	32.9	Very low	33.2	Very low	80 Å²	80	101.4 Å²	101.4	49%	0.491	53%	0.528	S	S	.	.	T	Hydrogen-bonded Turn	trans	-122.9	-14	-170.5	11	0	0	0	0	114.8	N12	N12-T14 VanDerWaalsContact CB-OG1 3.3Å; N12-T14 WeakPolarHBondContact CB-OG1 3.39Å; N12-T14 PolarHBondContact O-N 3.16Å
15	E	32.2	Very low	33.7	Very low	112 Å²	112	92.7 Å²	92.7	52%	0.523	51%	0.511	S	S	.	.	S	Bend	trans	-82.2	-34.3	179.2	-70.5	-175	154.7	0	0	112.8	L17 L18	E15-L17 PolarHBondContact O-N 2.86Å; E15-L18 PolarHBondContact O-N 3.5Å
16	H	33.6	Very low	34.1	Very low	82 Å²	82	89.2 Å²	89.2	38%	0.38	50%	0.497	S	S	.	.	T	Hydrogen-bonded Turn	trans	-50.4	-20.4	170.8	-106	-59	0	0	0	115.3	Q201 E202	H16-Q201 WeakPolarHBondContact CE1-CB 3.43Å; H16-Q201 VanDerWaalsContact CE1-CD 3.47Å; H16-Q201 PolarHBondContact CE1-OE1 3.48Å; H16-E202 IonicContact CD2-OE1 3.13Å; H16-E202 PolarHBondContact CD2-OE1 3.03Å; H16-E202 IonicContact CE1-OE1 3.92Å; H16-E202 IonicContact CG-OE1 3.51Å; H16-E202 PolarHBondContact N-OE1 3.36Å; H16-E202 IonicContact NE2-OE1 3.48Å; H16-E202 PolarHBondContact NE2-OE1 2.6Å
17	L	39.7	Very low	34.9	Very low	78 Å²	78	86.8 Å²	86.8	41%	0.408	49%	0.488	S	S	.	.	T	Hydrogen-bonded Turn	trans	-91.9	-8.8	-173.6	-71.4	165	0	0	0	113.1	E15 S21	E15-L17 PolarHBondContact O-N 2.86Å; L17-S21 WeakPolarHBondContact O-CA 3.39Å; L17-S21 WeakPolarHBondContact O-CB 3.32Å; L17-S21 PolarHBondContact O-N 3.49Å; L17-S21 PolarHBondContact O-OG 2.84Å
18	L	38.7	Very low	35.6	Very low	22 Å²	22	86.3 Å²	86.3	12%	0.115	49%	0.487	C	S	.	.	H	α-helix	trans	-72.4	-49.9	-169.9	-107.9	150.3	0	0	0	114.2	E15 S21 F22 T286	E15-L18 PolarHBondContact O-N 3.5Å; L18-S21 PolarHBondContact O-OG 3.36Å; L18-F22 HydrophobicContact CD2-CD2 4.04Å; L18-F22 HydrophobicContact CD2-CE1 4.49Å; L18-F22 HydrophobicContact CD2-CE2 3.29Å; L18-F22 HydrophobicContact CD2-CZ 3.58Å; L18-F22 VanDerWaalsContact O-CB 3.31Å; L18-F22 WeakPolarHBondContact O-CB 3.25Å; L18-F22 WeakPolarHBondContact O-CD2 3.3Å; L18-F22 WeakPolarHBondContact O-CG 3.29Å; L18-F22 PolarHBondContact O-N 2.9Å; L18-T286 HydrophobicContact CD1-CG2 4.43Å; L18-T286 HydrophobicContact CD2-CG2 3.51Å; L18-T286 HydrophobicContact CG-CG2 3.65Å
19	Y	38.3	Very low	35.8	Very low	76 Å²	76	85.7 Å²	85.7	30%	0.298	48%	0.483	S	S	.	.	H	α-helix	trans	-70.8	-42.9	176	-174.9	-99.3	0	0	0	112.1	F22 M23 F294	Y19-F22 PolarHBondContact O-N 3.39Å; Y19-M23 PolarHBondContact O-N 3.36Å; Y19-F294 HydrophobicContact CD2-CZ 4.47Å
20	D	39.5	Very low	36.7	Very low	40 Å²	40	88.9 Å²	88.9	21%	0.214	49%	0.491	C	S	.	.	H	α-helix	trans	-68.8	-38.5	177.1	-97.3	6.9	0	0	0	112	M23 Q24 K187	D20-M23 CarbonylContact O-C 3.58Å; D20-M23 PolarHBondContact O-N 3.48Å; D20-Q24 WeakPolarHBondContact O-CA 3.18Å; D20-Q24 WeakPolarHBondContact O-CB 3.2Å; D20-Q24 PolarHBondContact O-N 2.89Å; D20-K187 IonicContact OD2-NZ 2.7Å; D20-K187 PolarHBondContact OD2-NZ 3.3Å
21	S	42	Very low	37.3	Very low	12 Å²	12	90.9 Å²	90.9	8%	0.084	50%	0.495	C	S	.	.	H	α-helix	trans	-74.1	-28.4	173.4	76	0	0	0	0	111.7	L17 L18 M23 Q24 R291	L17-S21 WeakPolarHBondContact O-CA 3.39Å; L17-S21 WeakPolarHBondContact O-CB 3.32Å; L17-S21 PolarHBondContact O-N 3.49Å; L17-S21 PolarHBondContact O-OG 2.84Å; L18-S21 PolarHBondContact O-OG 3.36Å; S21-M23 PolarHBondContact O-N 2.7Å; S21-Q24 WeakPolarHBondContact CA-O 3.43Å; S21-Q24 CarbonylContact O-C 3.15Å; S21-Q24 PolarHBondContact O-N 3.45Å; S21-R291 PolarHBondContact O-NE 3.34Å; S21-R291 PolarHBondContact O-NH2 3.47Å
22	F	44.5	Very low	38	Very low	22 Å²	22	85.5 Å²	85.5	10%	0.096	48%	0.48	C	S	.	.	H	α-helix	trans	-64.6	-33	171.8	-80	-44.1	0	0	0	112	L18 Y19 L290 R291 F294	L18-F22 HydrophobicContact CD2-CD2 4.04Å; L18-F22 HydrophobicContact CD2-CE1 4.49Å; L18-F22 HydrophobicContact CD2-CE2 3.29Å; L18-F22 HydrophobicContact CD2-CZ 3.58Å; L18-F22 VanDerWaalsContact O-CB 3.31Å; L18-F22 WeakPolarHBondContact O-CB 3.25Å; L18-F22 WeakPolarHBondContact O-CD2 3.3Å; L18-F22 WeakPolarHBondContact O-CG 3.29Å; L18-F22 PolarHBondContact O-N 2.9Å; Y19-F22 PolarHBondContact O-N 3.39Å; F22-L290 HydrophobicContact CE1-CB 4.45Å; F22-L290 WeakPolarHBondContact CE1-O 3.44Å; F22-R291 HydrophobicContact CD1-CB 3.66Å; F22-R291 HydrophobicContact CD1-CG 3.9Å; F22-R291 HydrophobicContact CE1-CB 3.95Å; F22-F294 HydrophobicContact CB-CD1 3.65Å; F22-F294 HydrophobicContact CB-CE1 4.04Å; F22-F294 HydrophobicContact CD1-CB 4Å; F22-F294 HydrophobicContact CD1-CD1 4.24Å; F22-F294 HydrophobicContact CD1-CG 4.36Å; F22-F294 HydrophobicContact CD2-CB 4.19Å; F22-F294 AromaticContact CD2-CD1 3.59Å; F22-F294 HydrophobicContact CD2-CD1 3.59Å; F22-F294 HydrophobicContact CD2-CD2 4.34Å; F22-F294 AromaticContact CD2-CE1 3.97Å; F22-F294 HydrophobicContact CD2-CE1 3.97Å; F22-F294 AromaticContact CD2-CG 3.77Å; F22-F294 HydrophobicContact CD2-CG 3.77Å; F22-F294 HydrophobicContact CE1-CB 3.93Å; F22-F294 HydrophobicContact CE2-CB 4.12Å; F22-F294 HydrophobicContact CE2-CD1 4.25Å; F22-F294 HydrophobicContact CE2-CD2 4.28Å; F22-F294 AromaticContact CE2-CG 3.95Å; F22-F294 HydrophobicContact CE2-CG 3.95Å; F22-F294 HydrophobicContact CG-CB 4.14Å; F22-F294 AromaticContact CG-CD1 3.57Å; F22-F294 HydrophobicContact CG-CD1 3.57Å; F22-F294 HydrophobicContact CG-CE1 4.21Å; F22-F294 AromaticContact CG-CG 3.99Å; F22-F294 HydrophobicContact CG-CG 3.99Å; F22-F294 HydrophobicContact CZ-CB 3.98Å; F22-F294 HydrophobicContact CZ-CG 4.33Å
23	M	37.5	Very low	39.1	Very low	71 Å²	71	81.9 Å²	81.9	35%	0.35	47%	0.465	S	S	.	.	H	α-helix	trans	-87.7	-24.6	174.3	-72.1	-67.2	-73.1	0	0	114	Y19 D20 S21	Y19-M23 PolarHBondContact O-N 3.36Å; D20-M23 CarbonylContact O-C 3.58Å; D20-M23 PolarHBondContact O-N 3.48Å; S21-M23 PolarHBondContact O-N 2.7Å
24	Q	40.6	Very low	39.7	Very low	29 Å²	29	84.6 Å²	84.6	14%	0.136	47%	0.467	C	S	.	.	S	Bend	trans	-119.4	104.6	-171.4	-153.3	153.5	22.1	0	0	109.3	D20 S21 N26 K187 R291	D20-Q24 WeakPolarHBondContact O-CA 3.18Å; D20-Q24 WeakPolarHBondContact O-CB 3.2Å; D20-Q24 PolarHBondContact O-N 2.89Å; S21-Q24 WeakPolarHBondContact CA-O 3.43Å; S21-Q24 CarbonylContact O-C 3.15Å; S21-Q24 PolarHBondContact O-N 3.45Å; Q24-N26 PolarHBondContact O-N 3.06Å; Q24-K187 VanDerWaalsContact OE1-CD 3.32Å; Q24-R291 PolarHBondContact O-NH2 2.73Å
25	G	38.8	Very low	40.3	Very low	53 Å²	53	87.5 Å²	87.5	55%	0.546	48%	0.478	S	S	.	.			trans	-59.4	101.1	165.8	0	0	0	0	0	109
26	N	35	Very low	41.1	Very low	112 Å²	112	86 Å²	86	60%	0.599	47%	0.474	S	S	*	.			trans	-92.1	105	173.6	-143	30.9	0	0	0	108.2	Q24 S28	Q24-N26 PolarHBondContact O-N 3.06Å; N26-S28 PolarHBondContact O-N 3.07Å
27	E	44.3	Very low	41.8	Very low	140 Å²	140	86.2 Å²	86.2	65%	0.654	47%	0.474	S	S	*	.			trans	-70.5	114.6	164.3	-74.4	-166.3	126.3	0	0	109	H37	E27-H37 IonicContact OE1-CD2 3.14Å; E27-H37 PolarHBondContact OE1-CD2 3.2Å; E27-H37 IonicContact OE1-NE2 3.84Å
28	S	40.9	Very low	42.2	Very low	100 Å²	100	85.3 Å²	85.3	70%	0.699	48%	0.475	S	S	*	.			trans	-154.6	80.7	160.3	57.6	0	0	0	0	110.5	N26	N26-S28 PolarHBondContact O-N 3.07Å
29	S	34.5	Very low	42.8	Very low	105 Å²	105	88.8 Å²	88.8	73%	0.734	49%	0.489	S	S	*	.			trans	-176	109.6	142.1	52.4	0	0	0	0	110.5	N31	S29-N31 PolarHBondContact O-N 2.84Å; S29-N31 VanDerWaalsContact O-N 3.12Å
30	I	45.4	Very low	44	Very low	160 Å²	160	87.3 Å²	87.3	82%	0.821	49%	0.486	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.9	106.2	170.9	-63.8	170	0	0	0	107.6
31	N	40.9	Very low	45.4	Very low	161 Å²	161	91.1 Å²	91.1	86%	0.861	50%	0.503	S	S	*	.	T	Hydrogen-bonded Turn	trans	150.4	8.5	154.4	-75.9	-13.1	0	0	0	115.1	S29	S29-N31 PolarHBondContact O-N 2.84Å; S29-N31 VanDerWaalsContact O-N 3.12Å
32	G	43	Very low	46.9	Very low	54 Å²	54	94.8 Å²	94.8	56%	0.557	53%	0.525	S	S	*	.	S	Bend	trans	-125.3	14.8	172.4	0	0	0	0	0	115.7	Y34	G32-Y34 PolarHBondContact O-N 3.37Å
33	S	49.3	Very low	48.4	Very low	61 Å²	61	94.8 Å²	94.8	43%	0.427	53%	0.527	S	S	.	.	H	α-helix	trans	-71.7	-18.4	-149.9	46.6	0	0	0	0	118.5	H37	S33-H37 WeakPolarHBondContact O-CB 3.37Å; S33-H37 PolarHBondContact O-N 2.83Å
34	Y	42.1	Very low	50.4	Low	206 Å²	206	93.5 Å²	93.5	81%	0.808	52%	0.524	S	S	*	.	H	α-helix	trans	-82.3	-35.9	-171.4	-77.2	-82.7	0	0	0	114.8	G32 S38	G32-Y34 PolarHBondContact O-N 3.37Å; Y34-S38 PolarHBondContact O-OG 2.78Å
35	I	45.7	Very low	52.5	Low	141 Å²	141	96.5 Å²	96.5	72%	0.723	54%	0.544	S	S	*	.	H	α-helix	trans	-81	-37	-179.2	-59.9	-177.7	0	0	0	110.6	S38 F39	I35-S38 PolarHBondContact O-OG 3.16Å; I35-S38 VanDerWaalsContact O-OG 3.1Å; I35-F39 WeakPolarHBondContact O-CB 3.39Å; I35-F39 PolarHBondContact O-N 2.87Å; I35-F39 VanDerWaalsContact O-N 3.13Å
36	D	48.7	Very low	54.8	Low	82 Å²	82	97.6 Å²	97.6	44%	0.439	54%	0.54	S	S	.	.	H	α-helix	trans	-73.7	-37.8	-177.9	-133.5	-2.3	0	0	0	111.9	N40	D36-N40 VanDerWaalsContact O-CB 3.32Å; D36-N40 WeakPolarHBondContact O-CB 3.38Å; D36-N40 PolarHBondContact O-N 3.46Å; D36-N40 PolarHBondContact O-ND2 3.05Å
37	H	48.5	Very low	57.2	Low	85 Å²	85	93.3 Å²	93.3	39%	0.394	52%	0.517	S	S	.	.	H	α-helix	trans	-71	-35.4	178.7	-161	-51.8	0	0	0	112.8	E27 S33 Q41	E27-H37 IonicContact OE1-CD2 3.14Å; E27-H37 PolarHBondContact OE1-CD2 3.2Å; E27-H37 IonicContact OE1-NE2 3.84Å; S33-H37 WeakPolarHBondContact O-CB 3.37Å; S33-H37 PolarHBondContact O-N 2.83Å; H37-Q41 PolarHBondContact O-N 3.42Å; H37-Q41 VanDerWaalsContact O-N 3.1Å
38	S	48	Very low	59.2	Low	60 Å²	60	87.3 Å²	87.3	42%	0.42	49%	0.49	S	S	.	.	H	α-helix	trans	-75.1	-36.3	177.4	54.4	0	0	0	0	112.8	Y34 I35 T42	Y34-S38 PolarHBondContact O-OG 2.78Å; I35-S38 PolarHBondContact O-OG 3.16Å; I35-S38 VanDerWaalsContact O-OG 3.1Å; S38-T42 WeakPolarHBondContact O-CB 3.43Å; S38-T42 PolarHBondContact O-N 3.28Å; S38-T42 VanDerWaalsContact O-N 3.08Å; S38-T42 PolarHBondContact O-OG1 3.44Å
39	F	51.4	Low	61.6	Low	94 Å²	94	86.3 Å²	86.3	41%	0.412	48%	0.482	S	S	.	.	H	α-helix	trans	-65.7	-40	172.3	-175.6	-101	0	0	0	112	I35 S43 P288	I35-F39 WeakPolarHBondContact O-CB 3.39Å; I35-F39 PolarHBondContact O-N 2.87Å; I35-F39 VanDerWaalsContact O-N 3.13Å; F39-S43 VanDerWaalsContact O-CB 3.32Å; F39-S43 WeakPolarHBondContact O-CB 3.42Å; F39-S43 PolarHBondContact O-N 3.17Å; F39-S43 PolarHBondContact O-OG 2.97Å; F39-P288 HydrophobicContact CE1-CB 4.39Å
40	N	64.2	Low	64.3	Low	45 Å²	45	84.4 Å²	84.4	24%	0.241	46%	0.462	C	S	.	.	H	α-helix	trans	-68.1	-41.8	177.7	-77.1	-34	0	0	0	112.8	D36 T44	D36-N40 VanDerWaalsContact O-CB 3.32Å; D36-N40 WeakPolarHBondContact O-CB 3.38Å; D36-N40 PolarHBondContact O-N 3.46Å; D36-N40 PolarHBondContact O-ND2 3.05Å; N40-T44 WeakPolarHBondContact O-CB 3.47Å; N40-T44 PolarHBondContact O-N 3.34Å; N40-T44 PolarHBondContact O-OG1 2.98Å
41	Q	67.8	Low	66.5	Low	121 Å²	121	77.4 Å²	77.4	57%	0.565	43%	0.425	S	S	*	.	H	α-helix	trans	-65.9	-45.7	175.3	-88.6	-175.5	-30.2	0	0	112.3	H37 S43 T44 V45	H37-Q41 PolarHBondContact O-N 3.42Å; H37-Q41 VanDerWaalsContact O-N 3.1Å; Q41-S43 VanDerWaalsContact C-N 3.34Å; Q41-S43 PolarHBondContact O-N 2.95Å; Q41-T44 PolarHBondContact O-N 3.43Å; Q41-V45 WeakPolarHBondContact O-CG2 3.39Å; Q41-V45 PolarHBondContact O-N 3.46Å
42	T	74.8	Confident	69	Low	89 Å²	89	74.1 Å²	74.1	55%	0.546	40%	0.403	S	S	.	.	H	α-helix	trans	-61.3	-44.6	179.4	-56.7	0	0	0	0	111	S38 T44 V45 V46	S38-T42 WeakPolarHBondContact O-CB 3.43Å; S38-T42 PolarHBondContact O-N 3.28Å; S38-T42 VanDerWaalsContact O-N 3.08Å; S38-T42 PolarHBondContact O-OG1 3.44Å; T42-T44 PolarHBondContact O-N 3.47Å; T42-V45 PolarHBondContact O-N 3.25Å; T42-V46 HydrophobicContact CG2-CG2 4.48Å; T42-V46 WeakPolarHBondContact O-CB 3.47Å; T42-V46 VanDerWaalsContact O-CG2 3.27Å; T42-V46 WeakPolarHBondContact O-CG2 3.23Å; T42-V46 PolarHBondContact O-N 3.14Å
43	S	75.7	Confident	71.5	Confident	21 Å²	21	76.8 Å²	76.8	15%	0.147	41%	0.405	C	S	.	.	H	α-helix	trans	-60.4	-45.1	176.6	-62	0	0	0	0	111.6	F39 Q41 V45 V46 I47 S292	F39-S43 VanDerWaalsContact O-CB 3.32Å; F39-S43 WeakPolarHBondContact O-CB 3.42Å; F39-S43 PolarHBondContact O-N 3.17Å; F39-S43 PolarHBondContact O-OG 2.97Å; Q41-S43 VanDerWaalsContact C-N 3.34Å; Q41-S43 PolarHBondContact O-N 2.95Å; S43-V45 PolarHBondContact O-N 3.49Å; S43-V46 PolarHBondContact O-N 3.42Å; S43-I47 WeakPolarHBondContact O-CB 3.19Å; S43-I47 VanDerWaalsContact O-CD1 3.26Å; S43-I47 WeakPolarHBondContact O-CD1 3.46Å; S43-I47 WeakPolarHBondContact O-CG1 3.49Å; S43-I47 PolarHBondContact O-N 3.35Å; S43-S292 PolarHBondContact OG-OG 2.69Å
44	T	78.3	Confident	73.6	Confident	45 Å²	45	74.7 Å²	74.7	28%	0.276	39%	0.389	S	S	.	.	H	α-helix	trans	-62.4	-43.4	179.4	-56.5	0	0	0	0	112.2	N40 Q41 T42 I47 T48 L104	N40-T44 WeakPolarHBondContact O-CB 3.47Å; N40-T44 PolarHBondContact O-N 3.34Å; N40-T44 PolarHBondContact O-OG1 2.98Å; Q41-T44 PolarHBondContact O-N 3.43Å; T42-T44 PolarHBondContact O-N 3.47Å; T44-I47 PolarHBondContact O-N 2.92Å; T44-T48 VanDerWaalsContact O-CB 3.32Å; T44-T48 WeakPolarHBondContact O-CB 3.34Å; T44-T48 PolarHBondContact O-N 3.47Å; T44-T48 PolarHBondContact O-OG1 3.24Å; T44-L104 HydrophobicContact CG2-CD1 4.07Å; T44-L104 HydrophobicContact CG2-CG 4Å
45	V	85.2	Confident	76.1	Confident	91 Å²	91	65.3 Å²	65.3	55%	0.552	35%	0.353	S	S	*	.	H	α-helix	trans	-63.4	-46.6	176.3	172	0	0	0	0	110.8	Q41 T42 S43 I47 T48 C49	Q41-V45 WeakPolarHBondContact O-CG2 3.39Å; Q41-V45 PolarHBondContact O-N 3.46Å; T42-V45 PolarHBondContact O-N 3.25Å; S43-V45 PolarHBondContact O-N 3.49Å; V45-I47 PolarHBondContact O-N 2.92Å; V45-T48 PolarHBondContact O-N 3.33Å; V45-C49 WeakPolarHBondContact O-CB 3.28Å; V45-C49 PolarHBondContact O-N 3.2Å; V45-C49 PolarHBondContact O-SG 2.89Å
46	V	87.9	Confident	78.4	Confident	76 Å²	76	61 Å²	61	46%	0.461	34%	0.339	S	S	.	.	H	α-helix	trans	-60.7	-46.9	178.7	170.3	0	0	0	0	111.1	T42 S43 C49 M50	T42-V46 HydrophobicContact CG2-CG2 4.48Å; T42-V46 WeakPolarHBondContact O-CB 3.47Å; T42-V46 VanDerWaalsContact O-CG2 3.27Å; T42-V46 WeakPolarHBondContact O-CG2 3.23Å; T42-V46 PolarHBondContact O-N 3.14Å; S43-V46 PolarHBondContact O-N 3.42Å; V46-C49 PolarHBondContact O-N 2.85Å; V46-M50 HydrophobicContact CG1-SD 4.48Å; V46-M50 WeakPolarHBondContact O-CG 3.36Å; V46-M50 PolarHBondContact O-N 3.19Å
47	I	84.4	Confident	80.5	Confident	22 Å²	22	60.4 Å²	60.4	11%	0.113	34%	0.338	C	S	.	.	H	α-helix	trans	-63.3	-45	178.9	-64.3	157	0	0	0	110.3	S43 T44 V45 C49 M50 Y51 L104 A295 V299	S43-I47 WeakPolarHBondContact O-CB 3.19Å; S43-I47 VanDerWaalsContact O-CD1 3.26Å; S43-I47 WeakPolarHBondContact O-CD1 3.46Å; S43-I47 WeakPolarHBondContact O-CG1 3.49Å; S43-I47 PolarHBondContact O-N 3.35Å; T44-I47 PolarHBondContact O-N 2.92Å; V45-I47 PolarHBondContact O-N 2.92Å; I47-C49 VanDerWaalsContact C-N 3.35Å; I47-C49 PolarHBondContact O-N 3.48Å; I47-M50 WeakPolarHBondContact O-CB 3.2Å; I47-M50 PolarHBondContact O-N 2.88Å; I47-M50 VanDerWaalsContact O-N 3.11Å; I47-Y51 HydrophobicContact CG2-CD2 3.91Å; I47-Y51 HydrophobicContact CG2-CE2 3.5Å; I47-Y51 VanDerWaalsContact CG2-CE2 3.5Å; I47-Y51 WeakPolarHBondContact O-CD2 3.42Å; I47-Y51 PolarHBondContact O-N 2.86Å; I47-L104 HydrophobicContact CB-CD2 3.94Å; I47-L104 HydrophobicContact CG2-CD2 3.43Å; I47-L104 VanDerWaalsContact CG2-CD2 3.43Å; I47-A295 HydrophobicContact CD1-CB 3.42Å; I47-A295 VanDerWaalsContact CD1-CB 3.42Å; I47-A295 HydrophobicContact CG1-CB 4.09Å; I47-A295 HydrophobicContact CG2-CB 4.33Å; I47-V299 HydrophobicContact CG2-CG2 4.28Å
48	T	87.1	Confident	82.6	Confident	15 Å²	15	56.4 Å²	56.4	9%	0.092	32%	0.32	C	S	.	.	H	α-helix	trans	-58.1	-46.6	176.7	-59.6	0	0	0	0	111.4	T44 V45 M50 Y51 F52 A101 A105	T44-T48 VanDerWaalsContact O-CB 3.32Å; T44-T48 WeakPolarHBondContact O-CB 3.34Å; T44-T48 PolarHBondContact O-N 3.47Å; T44-T48 PolarHBondContact O-OG1 3.24Å; V45-T48 PolarHBondContact O-N 3.33Å; T48-M50 VanDerWaalsContact C-N 3.31Å; T48-M50 PolarHBondContact O-N 3.3Å; T48-Y51 PolarHBondContact O-N 3.16Å; T48-F52 HydrophobicContact CG2-CD2 3.99Å; T48-F52 HydrophobicContact CG2-CE2 3.7Å; T48-F52 VanDerWaalsContact O-CD2 3.29Å; T48-F52 WeakPolarHBondContact O-CD2 3.35Å; T48-F52 PolarHBondContact O-N 2.86Å; T48-A101 HydrophobicContact CG2-CB 4.46Å; T48-A105 HydrophobicContact CG2-CB 3.99Å
49	C	91.4	Very high	84.8	Confident	78 Å²	78	55.8 Å²	55.8	53%	0.527	31%	0.311	S	S	.	.	H	α-helix	trans	-60.5	-39.4	175.4	-73.1	0	0	0	0	112.2	V45 V46 I47 F52 L53	V45-C49 WeakPolarHBondContact O-CB 3.28Å; V45-C49 PolarHBondContact O-N 3.2Å; V45-C49 PolarHBondContact O-SG 2.89Å; V46-C49 PolarHBondContact O-N 2.85Å; I47-C49 VanDerWaalsContact C-N 3.35Å; I47-C49 PolarHBondContact O-N 3.48Å; C49-F52 PolarHBondContact O-N 3.08Å; C49-L53 WeakPolarHBondContact O-CB 3.45Å; C49-L53 PolarHBondContact O-N 3.03Å
50	M	91.5	Very high	86.8	Confident	66 Å²	66	55.7 Å²	55.7	33%	0.325	32%	0.321	S	S	.	.	H	α-helix	trans	-62.3	-40.9	175	-75.8	-177.5	147.8	0	0	112.3	V46 I47 T48 L53 V54 F296 V299	V46-M50 HydrophobicContact CG1-SD 4.48Å; V46-M50 WeakPolarHBondContact O-CG 3.36Å; V46-M50 PolarHBondContact O-N 3.19Å; I47-M50 WeakPolarHBondContact O-CB 3.2Å; I47-M50 PolarHBondContact O-N 2.88Å; I47-M50 VanDerWaalsContact O-N 3.11Å; T48-M50 VanDerWaalsContact C-N 3.31Å; T48-M50 PolarHBondContact O-N 3.3Å; M50-L53 PolarHBondContact O-N 2.88Å; M50-V54 WeakPolarHBondContact O-CB 3.45Å; M50-V54 VanDerWaalsContact O-CG2 3.29Å; M50-V54 WeakPolarHBondContact O-CG2 3.44Å; M50-V54 PolarHBondContact O-N 2.85Å; M50-F296 HydrophobicContact CE-CD2 4.42Å; M50-F296 HydrophobicContact CE-CE2 4.27Å; M50-F296 HydrophobicContact SD-CD2 4.5Å; M50-V299 HydrophobicContact CB-CG1 3.99Å; M50-V299 HydrophobicContact CB-CG2 4.26Å; M50-V299 HydrophobicContact SD-CG1 4.22Å
51	Y	90.5	Very high	88	Confident	13 Å²	13	54.3 Å²	54.3	5%	0.051	32%	0.318	C	S	.	.	H	α-helix	trans	-61.5	-46.2	177	-84.1	-129.3	0	0	0	111.4	I47 T48 V54 C55 L97 I100 A101 V298 V299 Y302	I47-Y51 HydrophobicContact CG2-CD2 3.91Å; I47-Y51 HydrophobicContact CG2-CE2 3.5Å; I47-Y51 VanDerWaalsContact CG2-CE2 3.5Å; I47-Y51 WeakPolarHBondContact O-CD2 3.42Å; I47-Y51 PolarHBondContact O-N 2.86Å; T48-Y51 PolarHBondContact O-N 3.16Å; Y51-V54 PolarHBondContact O-N 3.35Å; Y51-C55 VanDerWaalsContact O-CB 3.24Å; Y51-C55 WeakPolarHBondContact O-CB 3.4Å; Y51-C55 PolarHBondContact O-N 3.29Å; Y51-L97 HydrophobicContact CD1-CD2 4.23Å; Y51-I100 HydrophobicContact CD1-CB 4.45Å; Y51-I100 HydrophobicContact CD1-CG2 4.23Å; Y51-I100 HydrophobicContact CE1-CB 4.22Å; Y51-I100 HydrophobicContact CE1-CG2 3.57Å; Y51-A101 HydrophobicContact CD1-CB 4.29Å; Y51-A101 HydrophobicContact CG-CB 4.4Å; Y51-V298 WeakPolarHBondContact OH-CG1 3.38Å; Y51-V299 HydrophobicContact CD2-CG2 3.64Å; Y51-V299 HydrophobicContact CE2-CG2 3.34Å; Y51-Y302 HydrophobicContact CD1-CD2 4.5Å; Y51-Y302 HydrophobicContact CD1-CE2 4.11Å; Y51-Y302 HydrophobicContact CE1-CD2 4.17Å; Y51-Y302 AromaticContact CE1-CE2 3.41Å; Y51-Y302 HydrophobicContact CE1-CE2 3.41Å; Y51-Y302 VanDerWaalsContact CE1-CE2 3.41Å; Y51-Y302 HydrophobicContact CE2-CE2 4.22Å; Y51-Y302 AromaticContact CZ-CE2 3.49Å; Y51-Y302 VanDerWaalsContact CZ-CE2 3.49Å
52	F	94	Very high	89.2	Confident	91 Å²	91	48.6 Å²	48.6	40%	0.399	29%	0.291	S	S	.	.	H	α-helix	trans	-64.5	-39.7	176.4	-76	-64.3	0	0	0	112.5	T48 C49 C55 A56 P98 A101 I102	T48-F52 HydrophobicContact CG2-CD2 3.99Å; T48-F52 HydrophobicContact CG2-CE2 3.7Å; T48-F52 VanDerWaalsContact O-CD2 3.29Å; T48-F52 WeakPolarHBondContact O-CD2 3.35Å; T48-F52 PolarHBondContact O-N 2.86Å; C49-F52 PolarHBondContact O-N 3.08Å; F52-C55 PolarHBondContact O-N 3.05Å; F52-A56 WeakPolarHBondContact O-CB 3.43Å; F52-A56 PolarHBondContact O-N 3.17Å; F52-P98 HydrophobicContact CE1-CB 4.17Å; F52-A101 HydrophobicContact CD2-CB 4.17Å; F52-A101 HydrophobicContact CE1-CB 4.22Å; F52-A101 HydrophobicContact CE2-CB 3.75Å; F52-A101 HydrophobicContact CZ-CB 3.78Å; F52-I102 HydrophobicContact CZ-CG1 4.29Å
53	L	94.2	Very high	90.1	Very high	111 Å²	111	46.7 Å²	46.7	58%	0.581	29%	0.285	S	S	*	.	H	α-helix	trans	-62.7	-49	176.5	179.3	65.4	0	0	0	111.5	C49 M50 C55 A56 V57	C49-L53 WeakPolarHBondContact O-CB 3.45Å; C49-L53 PolarHBondContact O-N 3.03Å; M50-L53 PolarHBondContact O-N 2.88Å; L53-C55 VanDerWaalsContact C-N 3.34Å; L53-C55 PolarHBondContact O-N 2.99Å; L53-A56 PolarHBondContact O-N 3.49Å; L53-V57 HydrophobicContact CD1-CG2 4.26Å; L53-V57 WeakPolarHBondContact O-CG2 3.39Å; L53-V57 PolarHBondContact O-N 3.1Å
54	V	93.4	Very high	90.7	Very high	17 Å²	17	47.9 Å²	47.9	10%	0.103	29%	0.289	C	S	.	.	H	α-helix	trans	-61.4	-44.2	177.5	169.5	0	0	0	0	110.2	M50 Y51 A56 V57 G58 M94 L97 V299 C306	M50-V54 WeakPolarHBondContact O-CB 3.45Å; M50-V54 VanDerWaalsContact O-CG2 3.29Å; M50-V54 WeakPolarHBondContact O-CG2 3.44Å; M50-V54 PolarHBondContact O-N 2.85Å; Y51-V54 PolarHBondContact O-N 3.35Å; V54-A56 PolarHBondContact O-N 3.48Å; V54-V57 PolarHBondContact O-N 3.4Å; V54-G58 WeakPolarHBondContact O-CA 3.48Å; V54-G58 PolarHBondContact O-N 3.36Å; V54-M94 HydrophobicContact CG1-CE 4.04Å; V54-M94 HydrophobicContact CG1-SD 4.33Å; V54-L97 HydrophobicContact CG1-CD1 4.31Å; V54-V299 HydrophobicContact CG2-CG1 4.24Å; V54-C306 PolarHBondContact O-SG 2.93Å
55	C	94.5	Very high	91.2	Very high	8 Å²	8	46 Å²	46	5%	0.054	28%	0.278	C	S	.	.	H	α-helix	trans	-56.1	-50.5	174.1	178.6	0	0	0	0	112	Y51 F52 L53 G58 L59 M94 L97	Y51-C55 VanDerWaalsContact O-CB 3.24Å; Y51-C55 WeakPolarHBondContact O-CB 3.4Å; Y51-C55 PolarHBondContact O-N 3.29Å; F52-C55 PolarHBondContact O-N 3.05Å; L53-C55 VanDerWaalsContact C-N 3.34Å; L53-C55 PolarHBondContact O-N 2.99Å; C55-G58 PolarHBondContact O-N 2.88Å; C55-L59 WeakPolarHBondContact O-CB 3.2Å; C55-L59 VanDerWaalsContact O-CG 3.32Å; C55-L59 WeakPolarHBondContact O-CG 3.41Å; C55-L59 PolarHBondContact O-N 2.92Å; C55-M94 PolarHBondContact SG-O 3.45Å; C55-L97 HydrophobicContact CB-CB 4.21Å; C55-L97 HydrophobicContact CB-CD1 4.33Å
56	A	94.3	Very high	91.5	Very high	51 Å²	51	43.3 Å²	43.3	42%	0.421	26%	0.26	S	S	.	.	H	α-helix	trans	-62.7	-48.1	-178.9	0	0	0	0	0	112.3	F52 L53 V54 C60	F52-A56 WeakPolarHBondContact O-CB 3.43Å; F52-A56 PolarHBondContact O-N 3.17Å; L53-A56 PolarHBondContact O-N 3.49Å; V54-A56 PolarHBondContact O-N 3.48Å; A56-C60 WeakPolarHBondContact O-CB 3.35Å; A56-C60 PolarHBondContact O-N 3.46Å; A56-C60 PolarHBondContact O-SG 3.48Å
57	V	93.2	Very high	91.5	Very high	70 Å²	70	45 Å²	45	42%	0.424	26%	0.259	S	S	.	.	H	α-helix	trans	-63.1	-45.2	178.1	173.4	0	0	0	0	110.7	L53 V54 G61 C306	L53-V57 HydrophobicContact CD1-CG2 4.26Å; L53-V57 WeakPolarHBondContact O-CG2 3.39Å; L53-V57 PolarHBondContact O-N 3.1Å; V54-V57 PolarHBondContact O-N 3.4Å; V57-G61 PolarHBondContact O-N 3.11Å; V57-C306 HydrophobicContact CG1-CB 4.13Å
58	G	93.1	Very high	91.6	Very high	0 Å²	0	44 Å²	44	0%	0	25%	0.254	C	S	.	.	H	α-helix	trans	-64.1	-46.9	-179.4	0	0	0	0	0	112.7	V54 C55 N62 C306	V54-G58 WeakPolarHBondContact O-CA 3.48Å; V54-G58 PolarHBondContact O-N 3.36Å; C55-G58 PolarHBondContact O-N 2.88Å; G58-N62 VanDerWaalsContact O-CB 3.29Å; G58-N62 WeakPolarHBondContact O-CB 3.28Å; G58-N62 PolarHBondContact O-N 2.9Å; G58-N62 PolarHBondContact O-ND2 3.34Å; G58-C306 VanDerWaalsContact CA-SG 3.57Å; G58-C306 PolarHBondContact N-SG 3.24Å
59	L	94.3	Very high	91.5	Very high	47 Å²	47	44 Å²	44	25%	0.246	25%	0.253	C	S	.	.	H	α-helix	trans	-61.8	-51.3	176.1	-75.8	173.3	0	0	0	111.3	C55 G61 A63 V91 M94 L95	C55-L59 WeakPolarHBondContact O-CB 3.2Å; C55-L59 VanDerWaalsContact O-CG 3.32Å; C55-L59 WeakPolarHBondContact O-CG 3.41Å; C55-L59 PolarHBondContact O-N 2.92Å; L59-G61 PolarHBondContact O-N 3.32Å; L59-A63 WeakPolarHBondContact O-CB 3.37Å; L59-A63 PolarHBondContact O-N 3.43Å; L59-V91 HydrophobicContact CD2-CG1 4.14Å; L59-M94 HydrophobicContact CD2-CB 3.69Å; L59-M94 HydrophobicContact CG-CB 3.75Å; L59-L95 HydrophobicContact CD2-CD2 4.05Å; L59-L95 HydrophobicContact CD2-CG 4.26Å
60	C	92	Very high	91.2	Very high	92 Å²	92	46.1 Å²	46.1	62%	0.622	26%	0.258	S	S	*	.	H	α-helix	trans	-60.4	-47.3	-178.7	-67.3	0	0	0	0	111.4	A56 L64	A56-C60 WeakPolarHBondContact O-CB 3.35Å; A56-C60 PolarHBondContact O-N 3.46Å; A56-C60 PolarHBondContact O-SG 3.48Å; C60-L64 VanDerWaalsContact O-CB 3.26Å; C60-L64 WeakPolarHBondContact O-CB 3.43Å; C60-L64 PolarHBondContact O-N 2.89Å; C60-L64 VanDerWaalsContact O-N 3.12Å
61	G	91	Very high	90.7	Very high	17 Å²	17	51.4 Å²	51.4	18%	0.175	28%	0.275	C	S	.	.	H	α-helix	trans	-65	-50.8	-178.8	0	0	0	0	0	112.7	V57 L59 L64 V65	V57-G61 PolarHBondContact O-N 3.11Å; L59-G61 PolarHBondContact O-N 3.32Å; G61-L64 PolarHBondContact O-N 3.15Å; G61-V65 WeakPolarHBondContact O-CG2 3.36Å; G61-V65 PolarHBondContact O-N 3.31Å
62	N	93.1	Very high	90.1	Very high	0 Å²	0	54 Å²	54	0%	0	29%	0.285	C	S	.	.	H	α-helix	trans	-73.3	-35.1	-176.4	-72	-66.5	0	0	0	112.3	G58 L64 V65 I66 A87 D90 V91 S305 P309	G58-N62 VanDerWaalsContact O-CB 3.29Å; G58-N62 WeakPolarHBondContact O-CB 3.28Å; G58-N62 PolarHBondContact O-N 2.9Å; G58-N62 PolarHBondContact O-ND2 3.34Å; N62-L64 VanDerWaalsContact C-N 3.3Å; N62-L64 PolarHBondContact O-N 3.33Å; N62-V65 WeakPolarHBondContact O-CB 3.41Å; N62-V65 PolarHBondContact O-N 3.31Å; N62-I66 WeakPolarHBondContact O-CG1 3.43Å; N62-I66 PolarHBondContact O-N 3.05Å; N62-A87 HydrophobicContact CB-CB 4.29Å; N62-D90 HydrophobicContact CB-CB 4.31Å; N62-D90 PolarHBondContact OD1-OD2 2.88Å; N62-V91 HydrophobicContact CB-CG2 3.7Å; N62-S305 PolarHBondContact ND2-O 2.96Å; N62-P309 HydrophobicContact CB-CG 4.39Å; N62-P309 WeakPolarHBondContact OD1-CD 3.35Å; N62-P309 WeakPolarHBondContact OD1-CG 3.14Å
63	A	92.4	Very high	88.5	Confident	50 Å²	50	53.3 Å²	53.3	41%	0.413	30%	0.296	S	S	.	.	H	α-helix	trans	-61.6	-39.3	171.6	0	0	0	0	0	111.8	L59 I66 Y67	L59-A63 WeakPolarHBondContact O-CB 3.37Å; L59-A63 PolarHBondContact O-N 3.43Å; A63-I66 PolarHBondContact O-N 3.48Å; A63-Y67 WeakPolarHBondContact O-CB 3.38Å; A63-Y67 PolarHBondContact O-N 3.37Å
64	L	89.4	Confident	87	Confident	45 Å²	45	57.5 Å²	57.5	24%	0.236	31%	0.31	C	S	.	.	H	α-helix	trans	-66.3	-38.9	175.6	-177.5	51.6	0	0	0	112.2	C60 G61 N62 Y67 V68 F323 V326	C60-L64 VanDerWaalsContact O-CB 3.26Å; C60-L64 WeakPolarHBondContact O-CB 3.43Å; C60-L64 PolarHBondContact O-N 2.89Å; C60-L64 VanDerWaalsContact O-N 3.12Å; G61-L64 PolarHBondContact O-N 3.15Å; N62-L64 VanDerWaalsContact C-N 3.3Å; N62-L64 PolarHBondContact O-N 3.33Å; L64-Y67 HydrophobicContact CD1-CD1 4.2Å; L64-Y67 PolarHBondContact O-N 3.23Å; L64-V68 HydrophobicContact CD1-CG2 4.05Å; L64-V68 WeakPolarHBondContact O-CB 3.48Å; L64-V68 VanDerWaalsContact O-CG2 3.29Å; L64-V68 WeakPolarHBondContact O-CG2 3.42Å; L64-V68 PolarHBondContact O-N 2.8Å; L64-F323 HydrophobicContact CD2-CD2 3.76Å; L64-F323 HydrophobicContact CD2-CE2 3.16Å; L64-F323 HydrophobicContact CD2-CZ 3.94Å; L64-F323 HydrophobicContact CG-CD2 4.2Å; L64-F323 HydrophobicContact CG-CE2 3.99Å; L64-V326 HydrophobicContact CD1-CG1 4.34Å
65	V	89.1	Confident	85.8	Confident	7 Å²	7	57.1 Å²	57.1	4%	0.042	31%	0.307	C	S	.	.	H	α-helix	trans	-59.1	-47.8	172.1	170.4	0	0	0	0	110.8	G61 N62 V68 I69 I83 A87 P309 Y312 F319	G61-V65 WeakPolarHBondContact O-CG2 3.36Å; G61-V65 PolarHBondContact O-N 3.31Å; N62-V65 WeakPolarHBondContact O-CB 3.41Å; N62-V65 PolarHBondContact O-N 3.31Å; V65-V68 PolarHBondContact O-N 3Å; V65-I69 HydrophobicContact CG1-CD1 3.77Å; V65-I69 VanDerWaalsContact O-CG1 3.28Å; V65-I69 WeakPolarHBondContact O-CG1 3.14Å; V65-I69 PolarHBondContact O-N 3.11Å; V65-I83 HydrophobicContact CG1-CG2 3.69Å; V65-A87 HydrophobicContact CB-CB 4.2Å; V65-A87 HydrophobicContact CG1-CB 3.82Å; V65-P309 HydrophobicContact CG2-CB 3.94Å; V65-P309 HydrophobicContact CG2-CG 4.17Å; V65-Y312 HydrophobicContact CG2-CD2 4.31Å; V65-F319 HydrophobicContact CG1-CE1 4.11Å; V65-F319 HydrophobicContact CG1-CZ 4.49Å
66	I	90.9	Very high	84.6	Confident	34 Å²	34	64.6 Å²	64.6	17%	0.174	34%	0.338	C	S	.	.	H	α-helix	trans	-58.1	-51.9	176.3	-67.1	167.1	0	0	0	110.2	N62 A63 V68 I69 L70 L84 A87 V88 V91	N62-I66 WeakPolarHBondContact O-CG1 3.43Å; N62-I66 PolarHBondContact O-N 3.05Å; A63-I66 PolarHBondContact O-N 3.48Å; I66-V68 PolarHBondContact O-N 3.28Å; I66-I69 PolarHBondContact O-N 3.05Å; I66-L70 HydrophobicContact CG2-CD1 3.69Å; I66-L70 HydrophobicContact CG2-CG 4.29Å; I66-L70 WeakPolarHBondContact O-CB 3.4Å; I66-L70 VanDerWaalsContact O-CG 3.31Å; I66-L70 WeakPolarHBondContact O-CG 3.47Å; I66-L70 PolarHBondContact O-N 3.27Å; I66-L84 HydrophobicContact CB-CD1 4.2Å; I66-L84 HydrophobicContact CG1-CD1 3.97Å; I66-L84 HydrophobicContact CG2-CD1 4.07Å; I66-A87 HydrophobicContact CD1-CB 4.35Å; I66-A87 HydrophobicContact CG1-CB 3.81Å; I66-V88 HydrophobicContact CD1-CG2 3.99Å; I66-V88 HydrophobicContact CG1-CG2 4.33Å; I66-V91 HydrophobicContact CD1-CG2 3.9Å
67	Y	88.8	Confident	84	Confident	110 Å²	110	65.1 Å²	65.1	43%	0.431	34%	0.337	S	S	.	.	H	α-helix	trans	-55.7	-49.6	-179.6	172.8	-103.2	0	0	0	112.2	A63 L64 I69 L70 R71 V326	A63-Y67 WeakPolarHBondContact O-CB 3.38Å; A63-Y67 PolarHBondContact O-N 3.37Å; L64-Y67 HydrophobicContact CD1-CD1 4.2Å; L64-Y67 PolarHBondContact O-N 3.23Å; Y67-I69 PolarHBondContact O-N 3.17Å; Y67-L70 PolarHBondContact O-N 2.93Å; Y67-R71 VanDerWaalsContact O-CB 3.22Å; Y67-R71 WeakPolarHBondContact O-CB 3.23Å; Y67-R71 PolarHBondContact O-N 3.38Å; Y67-V326 HydrophobicContact CE1-CG1 4.26Å; Y67-V326 HydrophobicContact CE1-CG2 4.06Å
68	V	84.4	Confident	83.5	Confident	3 Å²	3	62.3 Å²	62.3	2%	0.018	32%	0.319	C	S	.	.	H	α-helix	trans	-60.8	-47.6	179.6	167.7	0	0	0	0	110.9	L64 V65 I66 L70 R71 Y72 F319 V326	L64-V68 HydrophobicContact CD1-CG2 4.05Å; L64-V68 WeakPolarHBondContact O-CB 3.48Å; L64-V68 VanDerWaalsContact O-CG2 3.29Å; L64-V68 WeakPolarHBondContact O-CG2 3.42Å; L64-V68 PolarHBondContact O-N 2.8Å; V65-V68 PolarHBondContact O-N 3Å; I66-V68 PolarHBondContact O-N 3.28Å; V68-L70 VanDerWaalsContact C-N 3.34Å; V68-L70 PolarHBondContact O-N 3.04Å; V68-R71 PolarHBondContact O-N 3.41Å; V68-Y72 HydrophobicContact CG1-CD2 3.94Å; V68-Y72 HydrophobicContact CG1-CE2 4.21Å; V68-Y72 WeakPolarHBondContact O-CD2 3.25Å; V68-Y72 PolarHBondContact O-N 3.01Å; V68-F319 HydrophobicContact CG1-CD1 4.08Å; V68-F319 HydrophobicContact CG1-CE1 4.17Å; V68-V326 HydrophobicContact CG2-CG2 4.49Å
69	I	85	Confident	82.9	Confident	14 Å²	14	63.3 Å²	63.3	7%	0.072	33%	0.325	C	S	.	.	H	α-helix	trans	-64.3	-40.8	-178	-65.1	167.9	0	0	0	111.5	V65 I66 Y67 M75 N80 I83 L84 F319	V65-I69 HydrophobicContact CG1-CD1 3.77Å; V65-I69 VanDerWaalsContact O-CG1 3.28Å; V65-I69 WeakPolarHBondContact O-CG1 3.14Å; V65-I69 PolarHBondContact O-N 3.11Å; I66-I69 PolarHBondContact O-N 3.05Å; Y67-I69 PolarHBondContact O-N 3.17Å; I69-M75 HydrophobicContact CG2-CB 4.49Å; I69-N80 HydrophobicContact CG2-CB 4.45Å; I69-I83 HydrophobicContact CD1-CB 4.28Å; I69-I83 HydrophobicContact CD1-CG2 3.8Å; I69-L84 HydrophobicContact CB-CD1 4.48Å; I69-L84 HydrophobicContact CD1-CB 3.93Å; I69-L84 HydrophobicContact CD1-CD1 4.42Å; I69-L84 HydrophobicContact CG2-CB 4.3Å; I69-L84 HydrophobicContact CG2-CD1 4.49Å; I69-L84 HydrophobicContact CG2-CD2 4.38Å; I69-F319 HydrophobicContact CD1-CE1 4.18Å; I69-F319 HydrophobicContact CD1-CZ 3.73Å; I69-F319 HydrophobicContact CG1-CE1 3.82Å; I69-F319 HydrophobicContact CG1-CZ 3.57Å
70	L	85.3	Confident	82.4	Confident	122 Å²	122	61.5 Å²	61.5	64%	0.639	32%	0.316	S	S	*	.	H	α-helix	trans	-71.5	-35.7	-179.6	-66.4	-179.7	0	0	0	112.4	I66 Y67 V68 L84	I66-L70 HydrophobicContact CG2-CD1 3.69Å; I66-L70 HydrophobicContact CG2-CG 4.29Å; I66-L70 WeakPolarHBondContact O-CB 3.4Å; I66-L70 VanDerWaalsContact O-CG 3.31Å; I66-L70 WeakPolarHBondContact O-CG 3.47Å; I66-L70 PolarHBondContact O-N 3.27Å; Y67-L70 PolarHBondContact O-N 2.93Å; V68-L70 VanDerWaalsContact C-N 3.34Å; V68-L70 PolarHBondContact O-N 3.04Å; L70-L84 HydrophobicContact CD2-CD2 4.23Å
71	R	82.6	Confident	82.2	Confident	177 Å²	177	58.4 Å²	58.4	67%	0.668	29%	0.293	S	S	*	.	H	α-helix	trans	-71.5	-38	-178.6	-176.3	64.5	-179	-174.6	2	113	Y67 V68	Y67-R71 VanDerWaalsContact O-CB 3.22Å; Y67-R71 WeakPolarHBondContact O-CB 3.23Å; Y67-R71 PolarHBondContact O-N 3.38Å; V68-R71 PolarHBondContact O-N 3.41Å
72	Y	77.4	Confident	82	Confident	68 Å²	68	58 Å²	58	27%	0.267	29%	0.286	S	S	.	.			trans	-97.2	104.3	-174.1	-67	-75.7	0	0	0	112.1	V68 K74 M75	V68-Y72 HydrophobicContact CG1-CD2 3.94Å; V68-Y72 HydrophobicContact CG1-CE2 4.21Å; V68-Y72 WeakPolarHBondContact O-CD2 3.25Å; V68-Y72 PolarHBondContact O-N 3.01Å; Y72-K74 PolarHBondContact O-N 3.18Å; Y72-M75 VanDerWaalsContact O-CB 3.27Å; Y72-M75 WeakPolarHBondContact O-CB 3.32Å; Y72-M75 PolarHBondContact O-N 3.19Å
73	A	59.7	Low	81.6	Confident	76 Å²	76	58.1 Å²	58.1	63%	0.628	29%	0.287	S	S	*	.	G	3₁₀ helix	trans	-56.7	-26.3	-179.3	0	0	0	0	0	114.6	M75	A73-M75 PolarHBondContact O-N 3.08Å
74	K	63.5	Low	81.5	Confident	200 Å²	200	57.7 Å²	57.7	87%	0.87	28%	0.278	S	S	*	.	G	3₁₀ helix	trans	-68.5	-10.9	174.4	-65.5	-175.9	-179.6	178.7	0	113.3	Y72	Y72-K74 PolarHBondContact O-N 3.18Å
75	M	67.4	Low	81.5	Confident	8 Å²	8	56.5 Å²	56.5	4%	0.039	27%	0.271	C	S	.	.	G	3₁₀ helix	trans	-90.7	10.5	-178.5	-64.4	-68.6	-85	0	0	113.8	I69 Y72 A73 T77 N80 N318 F319	I69-M75 HydrophobicContact CG2-CB 4.49Å; Y72-M75 VanDerWaalsContact O-CB 3.27Å; Y72-M75 WeakPolarHBondContact O-CB 3.32Å; Y72-M75 PolarHBondContact O-N 3.19Å; A73-M75 PolarHBondContact O-N 3.08Å; M75-T77 PolarHBondContact O-N 2.93Å; M75-N80 VanDerWaalsContact CA-ND2 3.29Å; M75-N80 WeakPolarHBondContact CA-ND2 3.38Å; M75-N80 WeakPolarHBondContact CB-ND2 3.48Å; M75-N80 WeakPolarHBondContact CE-ND2 3.31Å; M75-N80 WeakPolarHBondContact O-CB 3.4Å; M75-N80 PolarHBondContact O-ND2 3.41Å; M75-N80 PolarHBondContact SD-ND2 3.46Å; M75-N318 HydrophobicContact CE-CB 4.28Å; M75-N318 HydrophobicContact SD-CB 3.93Å; M75-F319 HydrophobicContact CE-CD2 3.73Å; M75-F319 HydrophobicContact CE-CE1 4.19Å; M75-F319 HydrophobicContact CE-CE2 3.36Å; M75-F319 HydrophobicContact CE-CG 4.3Å; M75-F319 HydrophobicContact CE-CZ 3.62Å
76	K	70.1	Confident	81.5	Confident	166 Å²	166	56.2 Å²	56.2	72%	0.722	27%	0.269	S	S	*	.			trans	-76.7	44.9	176.7	-64.2	-179.2	-179	177.9	0	113.8
77	T	81.8	Confident	81.6	Confident	62 Å²	62	54.6 Å²	54.6	38%	0.38	26%	0.261	S	S	.	.	S	Bend	trans	-93.3	157.1	177.3	73	0	0	0	0	111.3	M75 T79 N80 I81	M75-T77 PolarHBondContact O-N 2.93Å; T77-T79 VanDerWaalsContact C-N 3.3Å; T77-T79 PolarHBondContact O-N 3.41Å; T77-N80 PolarHBondContact O-N 3.19Å; T77-N80 VanDerWaalsContact O-N 3.09Å; T77-N80 PolarHBondContact OG1-N 3.32Å; T77-N80 PolarHBondContact OG1-ND2 3.49Å; T77-N80 VanDerWaalsContact OG1-ND2 3.1Å; T77-I81 WeakPolarHBondContact O-CG1 3.19Å; T77-I81 PolarHBondContact O-N 3.41Å
78	V	82.7	Confident	81.8	Confident	11 Å²	11	52 Å²	52	7%	0.067	26%	0.257	C	S	.	.	H	α-helix	trans	-54.3	-45	176.8	170.2	0	0	0	0	112.1	N80 I81 Y82 R155 A160	V78-N80 VanDerWaalsContact C-N 3.3Å; V78-N80 PolarHBondContact O-N 2.93Å; V78-I81 PolarHBondContact O-N 3.02Å; V78-Y82 HydrophobicContact CG1-CD2 4.02Å; V78-Y82 HydrophobicContact CG1-CE2 3.42Å; V78-Y82 VanDerWaalsContact CG1-CE2 3.42Å; V78-Y82 VanDerWaalsContact O-CD2 3.23Å; V78-Y82 WeakPolarHBondContact O-CD2 3.46Å; V78-Y82 PolarHBondContact O-N 3.34Å; V78-R155 HydrophobicContact CG2-CB 4.29Å; V78-R155 WeakPolarHBondContact CG2-O 3.49Å; V78-A160 HydrophobicContact CB-CB 4.45Å; V78-A160 HydrophobicContact CG1-CB 3.93Å; V78-A160 HydrophobicContact CG2-CB 4.3Å
79	T	79.9	Confident	82.2	Confident	20 Å²	20	52 Å²	52	12%	0.123	26%	0.257	C	S	.	.	H	α-helix	trans	-58.3	-43.4	177.1	-43.5	0	0	0	0	111.6	T77 I81 Y82 I83 M137 R141	T77-T79 VanDerWaalsContact C-N 3.3Å; T77-T79 PolarHBondContact O-N 3.41Å; T79-I81 VanDerWaalsContact C-N 3.31Å; T79-I81 PolarHBondContact O-N 3.29Å; T79-Y82 PolarHBondContact O-N 3.02Å; T79-I83 HydrophobicContact CG2-CD1 4.09Å; T79-I83 WeakPolarHBondContact O-CG1 3.4Å; T79-I83 PolarHBondContact O-N 3.35Å; T79-M137 HydrophobicContact CG2-CE 4.48Å; T79-R141 PolarHBondContact OG1-NH2 3.28Å
80	N	83.6	Confident	82.6	Confident	9 Å²	9	51.3 Å²	51.3	5%	0.048	25%	0.254	C	S	.	.	H	α-helix	trans	-72.8	-25.1	-177.8	-65.9	-16.1	0	0	0	112.5	I69 M75 T77 V78 L84	I69-N80 HydrophobicContact CG2-CB 4.45Å; M75-N80 VanDerWaalsContact CA-ND2 3.29Å; M75-N80 WeakPolarHBondContact CA-ND2 3.38Å; M75-N80 WeakPolarHBondContact CB-ND2 3.48Å; M75-N80 WeakPolarHBondContact CE-ND2 3.31Å; M75-N80 WeakPolarHBondContact O-CB 3.4Å; M75-N80 PolarHBondContact O-ND2 3.41Å; M75-N80 PolarHBondContact SD-ND2 3.46Å; T77-N80 PolarHBondContact O-N 3.19Å; T77-N80 VanDerWaalsContact O-N 3.09Å; T77-N80 PolarHBondContact OG1-N 3.32Å; T77-N80 PolarHBondContact OG1-ND2 3.49Å; T77-N80 VanDerWaalsContact OG1-ND2 3.1Å; V78-N80 VanDerWaalsContact C-N 3.3Å; V78-N80 PolarHBondContact O-N 2.93Å; N80-L84 VanDerWaalsContact O-CB 3.24Å; N80-L84 WeakPolarHBondContact O-CB 3.39Å; N80-L84 PolarHBondContact O-N 2.95Å
81	I	87.8	Confident	83	Confident	28 Å²	28	46.9 Å²	46.9	14%	0.144	23%	0.232	C	C	.	.	H	α-helix	trans	-66.3	-43.1	171.3	-66.5	168.1	0	0	0	110.1	T77 V78 T79 L84 N85 P157 A160 K161	T77-I81 WeakPolarHBondContact O-CG1 3.19Å; T77-I81 PolarHBondContact O-N 3.41Å; V78-I81 PolarHBondContact O-N 3.02Å; T79-I81 VanDerWaalsContact C-N 3.31Å; T79-I81 PolarHBondContact O-N 3.29Å; I81-L84 PolarHBondContact O-N 3.09Å; I81-N85 WeakPolarHBondContact O-CB 3.16Å; I81-N85 PolarHBondContact O-N 3.27Å; I81-P157 HydrophobicContact CD1-CB 3.76Å; I81-A160 HydrophobicContact CB-CB 4.45Å; I81-A160 HydrophobicContact CD1-CB 4.21Å; I81-A160 HydrophobicContact CG2-CB 4.22Å; I81-K161 HydrophobicContact CG2-CG 4.38Å
82	Y	86.5	Confident	83.5	Confident	8 Å²	8	42.4 Å²	42.4	3%	0.031	22%	0.221	C	C	.	.	H	α-helix	trans	-64.7	-43.2	174.6	-65.3	-57.7	0	0	0	112.2	V78 T79 L84 N85 L86 V136 M137 D140 I163 N164	V78-Y82 HydrophobicContact CG1-CD2 4.02Å; V78-Y82 HydrophobicContact CG1-CE2 3.42Å; V78-Y82 VanDerWaalsContact CG1-CE2 3.42Å; V78-Y82 VanDerWaalsContact O-CD2 3.23Å; V78-Y82 WeakPolarHBondContact O-CD2 3.46Å; V78-Y82 PolarHBondContact O-N 3.34Å; T79-Y82 PolarHBondContact O-N 3.02Å; Y82-L84 VanDerWaalsContact C-N 3.34Å; Y82-L84 PolarHBondContact O-N 3.43Å; Y82-N85 PolarHBondContact O-N 3.44Å; Y82-L86 PolarHBondContact O-N 3.4Å; Y82-V136 HydrophobicContact CD1-CG1 4.05Å; Y82-V136 HydrophobicContact CE1-CG1 3.35Å; Y82-V136 HydrophobicContact CE2-CG1 4.22Å; Y82-V136 VanDerWaalsContact CZ-CG1 3.44Å; Y82-V136 WeakPolarHBondContact OH-CG1 3.5Å; Y82-M137 HydrophobicContact CD2-CG 4.2Å; Y82-M137 HydrophobicContact CG-CG 3.97Å; Y82-D140 HydrophobicContact CE2-CB 4.31Å; Y82-I163 HydrophobicContact CE1-CG2 4.22Å; Y82-N164 WeakPolarHBondContact CD1-ND2 3.35Å; Y82-N164 WeakPolarHBondContact CD1-OD1 3.32Å; Y82-N164 WeakPolarHBondContact CE1-ND2 3.31Å
83	I	86.6	Confident	84.3	Confident	3 Å²	3	39.5 Å²	39.5	2%	0.015	21%	0.209	C	C	.	.	H	α-helix	trans	-61.1	-43.9	175.7	-67	169.6	0	0	0	111	V65 I69 T79 N85 L86 A87 M137 Y312 F319	V65-I83 HydrophobicContact CG1-CG2 3.69Å; I69-I83 HydrophobicContact CD1-CB 4.28Å; I69-I83 HydrophobicContact CD1-CG2 3.8Å; T79-I83 HydrophobicContact CG2-CD1 4.09Å; T79-I83 WeakPolarHBondContact O-CG1 3.4Å; T79-I83 PolarHBondContact O-N 3.35Å; I83-N85 VanDerWaalsContact C-N 3.32Å; I83-N85 PolarHBondContact O-N 3.47Å; I83-L86 PolarHBondContact O-N 2.85Å; I83-A87 WeakPolarHBondContact O-CB 3.39Å; I83-A87 PolarHBondContact O-N 2.85Å; I83-M137 HydrophobicContact CG1-CE 4.14Å; I83-Y312 HydrophobicContact CB-CE2 4.42Å; I83-Y312 HydrophobicContact CD1-CD1 4.25Å; I83-Y312 HydrophobicContact CD1-CE1 4.14Å; I83-Y312 HydrophobicContact CG1-CE1 4.01Å; I83-Y312 HydrophobicContact CG1-CE2 4.33Å; I83-Y312 HydrophobicContact CG2-CD2 3.76Å; I83-Y312 HydrophobicContact CG2-CE2 3.5Å; I83-Y312 HydrophobicContact CG2-CG 4.4Å; I83-F319 HydrophobicContact CD1-CE2 3.99Å; I83-F319 HydrophobicContact CD1-CZ 4.43Å; I83-F319 HydrophobicContact CG2-CZ 4.01Å
84	L	88.8	Confident	85.9	Confident	41 Å²	41	35.9 Å²	35.9	22%	0.215	18%	0.179	C	C	.	.	H	α-helix	trans	-61.4	-43.2	176.5	179.4	65.3	0	0	0	111.1	I66 I69 L70 N80 I81 Y82 A87 V88	I66-L84 HydrophobicContact CB-CD1 4.2Å; I66-L84 HydrophobicContact CG1-CD1 3.97Å; I66-L84 HydrophobicContact CG2-CD1 4.07Å; I69-L84 HydrophobicContact CB-CD1 4.48Å; I69-L84 HydrophobicContact CD1-CB 3.93Å; I69-L84 HydrophobicContact CD1-CD1 4.42Å; I69-L84 HydrophobicContact CG2-CB 4.3Å; I69-L84 HydrophobicContact CG2-CD1 4.49Å; I69-L84 HydrophobicContact CG2-CD2 4.38Å; L70-L84 HydrophobicContact CD2-CD2 4.23Å; N80-L84 VanDerWaalsContact O-CB 3.24Å; N80-L84 WeakPolarHBondContact O-CB 3.39Å; N80-L84 PolarHBondContact O-N 2.95Å; I81-L84 PolarHBondContact O-N 3.09Å; Y82-L84 VanDerWaalsContact C-N 3.34Å; Y82-L84 PolarHBondContact O-N 3.43Å; L84-A87 PolarHBondContact O-N 2.91Å; L84-V88 WeakPolarHBondContact O-CG2 3.2Å; L84-V88 PolarHBondContact O-N 3.37Å
85	N	90.3	Very high	87.4	Confident	19 Å²	19	30.9 Å²	30.9	10%	0.102	16%	0.161	C	C	.	.	H	α-helix	trans	-62.5	-44.7	178.7	-169	33.9	0	0	0	112	I81 Y82 I83 A87 V88 A89 N164 W168	I81-N85 WeakPolarHBondContact O-CB 3.16Å; I81-N85 PolarHBondContact O-N 3.27Å; Y82-N85 PolarHBondContact O-N 3.44Å; I83-N85 VanDerWaalsContact C-N 3.32Å; I83-N85 PolarHBondContact O-N 3.47Å; N85-A87 PolarHBondContact O-N 3.27Å; N85-V88 PolarHBondContact O-N 3.34Å; N85-A89 PolarHBondContact O-N 2.75Å; N85-N164 HydrophobicContact CB-CB 4.42Å; N85-N164 VanDerWaalsContact CB-OD1 3.25Å; N85-N164 WeakPolarHBondContact CB-OD1 3Å; N85-N164 VanDerWaalsContact CG-OD1 3.31Å; N85-N164 WeakPolarHBondContact ND2-CB 3.33Å; N85-N164 PolarHBondContact ND2-OD1 2.63Å; N85-W168 PolarHBondContact ND2-NE1 3.42Å; N85-W168 PolarHBondContact OD1-NE1 3.3Å
86	L	89.1	Confident	88.6	Confident	1 Å²	1	30.9 Å²	30.9	1%	0.005	16%	0.164	C	C	.	.	H	α-helix	trans	-60.5	-45.4	176	-171.7	65.8	0	0	0	111.4	Y82 I83 V88 A89 D90 S130 C133 N308 Y312	Y82-L86 PolarHBondContact O-N 3.4Å; I83-L86 PolarHBondContact O-N 2.85Å; L86-V88 VanDerWaalsContact C-N 3.31Å; L86-V88 PolarHBondContact O-N 3.48Å; L86-A89 PolarHBondContact O-N 3.2Å; L86-D90 WeakPolarHBondContact O-CB 3.5Å; L86-D90 PolarHBondContact O-N 3.14Å; L86-S130 WeakPolarHBondContact CD1-OG 3.48Å; L86-C133 HydrophobicContact CD1-CB 4.35Å; L86-N308 HydrophobicContact CD2-CB 4.38Å; L86-Y312 VanDerWaalsContact CD2-OH 3.25Å; L86-Y312 WeakPolarHBondContact CD2-OH 3.38Å
87	A	92.1	Very high	89.6	Confident	1 Å²	1	23 Å²	23	1%	0.008	13%	0.13	C	C	.	.	H	α-helix	trans	-63.3	-35.1	178.2	0	0	0	0	0	112.9	N62 V65 I66 I83 L84 N85 V91	N62-A87 HydrophobicContact CB-CB 4.29Å; V65-A87 HydrophobicContact CB-CB 4.2Å; V65-A87 HydrophobicContact CG1-CB 3.82Å; I66-A87 HydrophobicContact CD1-CB 4.35Å; I66-A87 HydrophobicContact CG1-CB 3.81Å; I83-A87 WeakPolarHBondContact O-CB 3.39Å; I83-A87 PolarHBondContact O-N 2.85Å; L84-A87 PolarHBondContact O-N 2.91Å; N85-A87 PolarHBondContact O-N 3.27Å; A87-V91 WeakPolarHBondContact O-CG2 3.23Å; A87-V91 PolarHBondContact O-N 3.41Å
88	V	92.5	Very high	90.2	Very high	55 Å²	55	21.7 Å²	21.7	33%	0.333	12%	0.122	S	C	.	.	H	α-helix	trans	-66.8	-44.1	174	169.6	0	0	0	0	111.1	I66 L84 N85 L86 V91 L92	I66-V88 HydrophobicContact CD1-CG2 3.99Å; I66-V88 HydrophobicContact CG1-CG2 4.33Å; L84-V88 WeakPolarHBondContact O-CG2 3.2Å; L84-V88 PolarHBondContact O-N 3.37Å; N85-V88 PolarHBondContact O-N 3.34Å; L86-V88 VanDerWaalsContact C-N 3.31Å; L86-V88 PolarHBondContact O-N 3.48Å; V88-V91 PolarHBondContact O-N 2.96Å; V88-L92 HydrophobicContact CG1-CD1 4.22Å; V88-L92 WeakPolarHBondContact O-CG 3.38Å; V88-L92 PolarHBondContact O-N 2.82Å
89	A	92.9	Very high	90.7	Very high	3 Å²	3	24.1 Å²	24.1	3%	0.025	13%	0.132	C	C	.	.	H	α-helix	trans	-60.6	-46.3	175.3	0	0	0	0	0	111.6	N85 L86 V91 L92 F93 N126 T129 W168	N85-A89 PolarHBondContact O-N 2.75Å; L86-A89 PolarHBondContact O-N 3.2Å; A89-V91 PolarHBondContact O-N 3.37Å; A89-L92 PolarHBondContact O-N 3.44Å; A89-F93 WeakPolarHBondContact O-CB 3.43Å; A89-F93 PolarHBondContact O-N 3.29Å; A89-N126 PolarHBondContact O-OD1 3.11Å; A89-T129 HydrophobicContact CB-CG2 3.92Å; A89-W168 HydrophobicContact CB-CH2 3.86Å; A89-W168 HydrophobicContact CB-CZ2 3.94Å
90	D	93.8	Very high	91.1	Very high	0 Å²	0	23.9 Å²	23.9	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-62.6	-38.7	177.8	-74.2	-31.3	0	0	0	112.3	N62 L86 F93 M94 S305 N308	N62-D90 HydrophobicContact CB-CB 4.31Å; N62-D90 PolarHBondContact OD1-OD2 2.88Å; L86-D90 WeakPolarHBondContact O-CB 3.5Å; L86-D90 PolarHBondContact O-N 3.14Å; D90-F93 WeakPolarHBondContact O-CB 3.28Å; D90-F93 PolarHBondContact O-N 2.92Å; D90-M94 WeakPolarHBondContact O-CB 3.47Å; D90-M94 WeakPolarHBondContact O-CG 3.06Å; D90-M94 PolarHBondContact O-N 3.26Å; D90-S305 WeakPolarHBondContact OD1-CB 3.48Å; D90-S305 PolarHBondContact OD1-OG 3Å; D90-N308 PolarHBondContact OD2-ND2 3.35Å
91	V	94.8	Very high	91.3	Very high	29 Å²	29	23.4 Å²	23.4	18%	0.176	13%	0.127	C	C	.	.	H	α-helix	trans	-65.8	-47.2	175.3	166.6	0	0	0	0	111.2	L59 N62 I66 A87 V88 A89 F93 M94 L95	L59-V91 HydrophobicContact CD2-CG1 4.14Å; N62-V91 HydrophobicContact CB-CG2 3.7Å; I66-V91 HydrophobicContact CD1-CG2 3.9Å; A87-V91 WeakPolarHBondContact O-CG2 3.23Å; A87-V91 PolarHBondContact O-N 3.41Å; V88-V91 PolarHBondContact O-N 2.96Å; A89-V91 PolarHBondContact O-N 3.37Å; V91-F93 PolarHBondContact O-N 3.29Å; V91-M94 PolarHBondContact O-N 3.17Å; V91-L95 HydrophobicContact CG1-CD1 4.4Å; V91-L95 WeakPolarHBondContact O-CG 3.31Å; V91-L95 PolarHBondContact O-N 2.94Å; V91-L95 VanDerWaalsContact O-N 3.08Å
92	L	93.3	Very high	91.4	Very high	83 Å²	83	24.6 Å²	24.6	44%	0.435	13%	0.133	S	C	.	.	H	α-helix	trans	-57.4	-43.4	177.8	-73.1	171.1	0	0	0	111	V88 A89 L95 V122 W168	V88-L92 HydrophobicContact CG1-CD1 4.22Å; V88-L92 WeakPolarHBondContact O-CG 3.38Å; V88-L92 PolarHBondContact O-N 2.82Å; A89-L92 PolarHBondContact O-N 3.44Å; L92-L95 PolarHBondContact O-N 3.43Å; L92-V122 HydrophobicContact CB-CG1 4.4Å; L92-V122 VanDerWaalsContact O-CG1 3.27Å; L92-V122 WeakPolarHBondContact O-CG1 3.44Å; L92-W168 HydrophobicContact CD1-CH2 3.88Å; L92-W168 HydrophobicContact CD1-CZ3 4.47Å
93	F	93.4	Very high	91.4	Very high	6 Å²	6	24.6 Å²	24.6	3%	0.026	13%	0.134	C	C	.	.	H	α-helix	trans	-57.9	-51.1	174	173.6	-123.9	0	0	0	113.2	A89 D90 V91 L95 G96 L97 D123 N126 Y302	A89-F93 WeakPolarHBondContact O-CB 3.43Å; A89-F93 PolarHBondContact O-N 3.29Å; D90-F93 WeakPolarHBondContact O-CB 3.28Å; D90-F93 PolarHBondContact O-N 2.92Å; V91-F93 PolarHBondContact O-N 3.29Å; F93-L95 PolarHBondContact O-N 2.92Å; F93-G96 PolarHBondContact O-N 3.27Å; F93-L97 HydrophobicContact CE1-CD1 4.17Å; F93-L97 HydrophobicContact CE1-CG 4.49Å; F93-L97 HydrophobicContact CE2-CD2 4.16Å; F93-L97 HydrophobicContact CE2-CG 4.27Å; F93-L97 HydrophobicContact CZ-CD1 4.05Å; F93-L97 HydrophobicContact CZ-CD2 3.82Å; F93-L97 HydrophobicContact CZ-CG 3.95Å; F93-D123 HydrophobicContact CE2-CB 4.33Å; F93-D123 WeakPolarHBondContact CE2-OD1 3.36Å; F93-N126 HydrophobicContact CB-CB 3.59Å; F93-N126 VanDerWaalsContact CB-CG 3.45Å; F93-N126 HydrophobicContact CD1-CB 4.46Å; F93-N126 WeakPolarHBondContact CD1-ND2 3.4Å; F93-N126 HydrophobicContact CD2-CB 3.98Å; F93-N126 HydrophobicContact CG-CB 3.72Å; F93-N126 VanDerWaalsContact CG-ND2 3.3Å; F93-N126 WeakPolarHBondContact CG-ND2 3.41Å; F93-Y302 HydrophobicContact CE1-CD1 4.01Å; F93-Y302 HydrophobicContact CE1-CG 4.45Å; F93-Y302 HydrophobicContact CE2-CD1 4.15Å; F93-Y302 HydrophobicContact CE2-CE1 4.11Å; F93-Y302 AromaticContact CZ-CD1 3.25Å; F93-Y302 HydrophobicContact CZ-CD1 3.25Å; F93-Y302 AromaticContact CZ-CE1 3.64Å; F93-Y302 HydrophobicContact CZ-CE1 3.64Å; F93-Y302 AromaticContact CZ-CG 3.9Å; F93-Y302 HydrophobicContact CZ-CG 3.9Å
94	M	94.1	Very high	91.2	Very high	0 Å²	0	25.8 Å²	25.8	0%	0	14%	0.14	C	C	.	.	H	α-helix	trans	-65.5	-24.1	-177.4	-67.7	-78.8	166.6	0	0	113.2	V54 C55 L59 D90 V91 G96 L97 P98	V54-M94 HydrophobicContact CG1-CE 4.04Å; V54-M94 HydrophobicContact CG1-SD 4.33Å; C55-M94 PolarHBondContact SG-O 3.45Å; L59-M94 HydrophobicContact CD2-CB 3.69Å; L59-M94 HydrophobicContact CG-CB 3.75Å; D90-M94 WeakPolarHBondContact O-CB 3.47Å; D90-M94 WeakPolarHBondContact O-CG 3.06Å; D90-M94 PolarHBondContact O-N 3.26Å; V91-M94 PolarHBondContact O-N 3.17Å; M94-G96 VanDerWaalsContact C-N 3.26Å; M94-G96 PolarHBondContact O-N 3.36Å; M94-L97 HydrophobicContact CE-CD1 4.31Å; M94-L97 HydrophobicContact SD-CD1 3.49Å; M94-L97 WeakPolarHBondContact SD-CD1 3.43Å; M94-P98 VanDerWaalsContact O-CD 3.28Å; M94-P98 WeakPolarHBondContact O-CD 3.19Å
95	L	93.9	Very high	91	Very high	95 Å²	95	26.5 Å²	26.5	50%	0.497	15%	0.151	S	C	.	.	H	α-helix	trans	-69.2	-23.5	172.5	-68	172.8	0	0	0	112.9	L59 V91 L92 F93 F99	L59-L95 HydrophobicContact CD2-CD2 4.05Å; L59-L95 HydrophobicContact CD2-CG 4.26Å; V91-L95 HydrophobicContact CG1-CD1 4.4Å; V91-L95 WeakPolarHBondContact O-CG 3.31Å; V91-L95 PolarHBondContact O-N 2.94Å; V91-L95 VanDerWaalsContact O-N 3.08Å; L92-L95 PolarHBondContact O-N 3.43Å; F93-L95 PolarHBondContact O-N 2.92Å; L95-F99 WeakPolarHBondContact O-CE2 3.3Å
96	G	92.1	Very high	90.7	Very high	9 Å²	9	29.6 Å²	29.6	9%	0.093	17%	0.168	C	C	.	.	H	α-helix	trans	-79.9	-31.1	176.1	0	0	0	0	0	113.8	F93 M94 P98 F99	F93-G96 PolarHBondContact O-N 3.27Å; M94-G96 VanDerWaalsContact C-N 3.26Å; M94-G96 PolarHBondContact O-N 3.36Å; G96-P98 VanDerWaalsContact C-CD 3.49Å; G96-F99 WeakPolarHBondContact O-CB 3.33Å; G96-F99 PolarHBondContact O-N 2.89Å; G96-F99 VanDerWaalsContact O-N 3.08Å
97	L	91.7	Very high	90.4	Very high	1 Å²	1	33.2 Å²	33.2	1%	0.005	19%	0.189	C	C	.	.	H	α-helix	trans	-56.1	-39.6	-175.1	-76.5	178.8	0	0	0	115.4	Y51 V54 C55 F93 M94 F99 I100 A101 Y302	Y51-L97 HydrophobicContact CD1-CD2 4.23Å; V54-L97 HydrophobicContact CG1-CD1 4.31Å; C55-L97 HydrophobicContact CB-CB 4.21Å; C55-L97 HydrophobicContact CB-CD1 4.33Å; F93-L97 HydrophobicContact CE1-CD1 4.17Å; F93-L97 HydrophobicContact CE1-CG 4.49Å; F93-L97 HydrophobicContact CE2-CD2 4.16Å; F93-L97 HydrophobicContact CE2-CG 4.27Å; F93-L97 HydrophobicContact CZ-CD1 4.05Å; F93-L97 HydrophobicContact CZ-CD2 3.82Å; F93-L97 HydrophobicContact CZ-CG 3.95Å; M94-L97 HydrophobicContact CE-CD1 4.31Å; M94-L97 HydrophobicContact SD-CD1 3.49Å; M94-L97 WeakPolarHBondContact SD-CD1 3.43Å; L97-F99 PolarHBondContact O-N 3.48Å; L97-I100 PolarHBondContact O-N 3.45Å; L97-A101 WeakPolarHBondContact O-CB 3.48Å; L97-A101 PolarHBondContact O-N 3.47Å; L97-Y302 HydrophobicContact CD2-CD1 4.26Å; L97-Y302 HydrophobicContact CD2-CD2 3.68Å; L97-Y302 HydrophobicContact CD2-CE1 4.18Å; L97-Y302 HydrophobicContact CD2-CE2 3.66Å; L97-Y302 HydrophobicContact CD2-CG 3.97Å
98	P	94.1	Very high	89.9	Confident	34 Å²	34	36.5 Å²	36.5	22%	0.221	21%	0.205	C	C	.	.	H	α-helix	trans	-57.5	-35.4	176.3	-28.1	36.4	0	0	0	113.3	F52 M94 G96 A101 I102	F52-P98 HydrophobicContact CE1-CB 4.17Å; M94-P98 VanDerWaalsContact O-CD 3.28Å; M94-P98 WeakPolarHBondContact O-CD 3.19Å; G96-P98 VanDerWaalsContact C-CD 3.49Å; P98-A101 PolarHBondContact O-N 2.88Å; P98-I102 WeakPolarHBondContact O-CB 3.27Å; P98-I102 WeakPolarHBondContact O-CD1 3.36Å; P98-I102 WeakPolarHBondContact O-CG1 3.22Å; P98-I102 PolarHBondContact O-N 3.46Å
99	F	92.9	Very high	89.7	Confident	62 Å²	62	34.2 Å²	34.2	27%	0.272	19%	0.19	S	C	.	.	H	α-helix	trans	-69.1	-39.9	179.2	-60	-79.5	0	0	0	111.6	L95 G96 L97 I102 Q103 W109 F111 L115 V119	L95-F99 WeakPolarHBondContact O-CE2 3.3Å; G96-F99 WeakPolarHBondContact O-CB 3.33Å; G96-F99 PolarHBondContact O-N 2.89Å; G96-F99 VanDerWaalsContact O-N 3.08Å; L97-F99 PolarHBondContact O-N 3.48Å; F99-I102 PolarHBondContact O-N 2.92Å; F99-Q103 PolarHBondContact O-N 3.08Å; F99-W109 HydrophobicContact CB-CH2 3.75Å; F99-W109 HydrophobicContact CB-CZ3 4.03Å; F99-F111 HydrophobicContact CB-CD2 4.44Å; F99-F111 HydrophobicContact CB-CE2 4.18Å; F99-F111 AromaticContact CD1-CD1 4Å; F99-F111 HydrophobicContact CD1-CD1 4Å; F99-F111 AromaticContact CD1-CD2 3.95Å; F99-F111 HydrophobicContact CD1-CD2 3.95Å; F99-F111 AromaticContact CD1-CE1 3.85Å; F99-F111 HydrophobicContact CD1-CE1 3.85Å; F99-F111 AromaticContact CD1-CE2 3.8Å; F99-F111 HydrophobicContact CD1-CE2 3.8Å; F99-F111 HydrophobicContact CD1-CG 4.05Å; F99-F111 AromaticContact CD1-CZ 3.74Å; F99-F111 HydrophobicContact CD1-CZ 3.74Å; F99-F111 HydrophobicContact CE1-CD1 4.22Å; F99-F111 HydrophobicContact CE1-CE1 4.13Å; F99-F111 HydrophobicContact CE1-CZ 4.43Å; F99-L115 HydrophobicContact CD1-CD2 3.51Å; F99-L115 HydrophobicContact CD1-CG 4.46Å; F99-L115 HydrophobicContact CE1-CD2 3.38Å; F99-L115 HydrophobicContact CG-CD2 4.21Å; F99-L115 HydrophobicContact CZ-CD2 3.98Å; F99-V119 HydrophobicContact CB-CG1 4.46Å; F99-V119 HydrophobicContact CB-CG2 4.03Å; F99-V119 HydrophobicContact CD2-CG2 3.92Å; F99-V119 HydrophobicContact CG-CG2 4.1Å
100	I	88.9	Confident	89.6	Confident	14 Å²	14	37.2 Å²	37.2	7%	0.072	21%	0.209	C	C	.	.	H	α-helix	trans	-66.7	-41.1	173.7	-55.3	-59.8	0	0	0	110.8	Y51 L97 I102 Q103 L104 W109 V119	Y51-I100 HydrophobicContact CD1-CB 4.45Å; Y51-I100 HydrophobicContact CD1-CG2 4.23Å; Y51-I100 HydrophobicContact CE1-CB 4.22Å; Y51-I100 HydrophobicContact CE1-CG2 3.57Å; L97-I100 PolarHBondContact O-N 3.45Å; I100-I102 VanDerWaalsContact C-N 3.33Å; I100-I102 PolarHBondContact O-N 3.29Å; I100-Q103 WeakPolarHBondContact O-CB 3.47Å; I100-Q103 PolarHBondContact O-N 3.41Å; I100-L104 PolarHBondContact O-N 2.86Å; I100-W109 HydrophobicContact CD1-CZ3 4.39Å; I100-V119 HydrophobicContact CD1-CG1 3.51Å; I100-V119 HydrophobicContact CG1-CG1 3.74Å
101	A	88.8	Confident	89.6	Confident	0 Å²	0	40.4 Å²	40.4	0%	0	22%	0.223	C	C	.	.	H	α-helix	trans	-61.5	-41	175.9	0	0	0	0	0	111.9	T48 Y51 F52 L97 P98 L104 A105	T48-A101 HydrophobicContact CG2-CB 4.46Å; Y51-A101 HydrophobicContact CD1-CB 4.29Å; Y51-A101 HydrophobicContact CG-CB 4.4Å; F52-A101 HydrophobicContact CD2-CB 4.17Å; F52-A101 HydrophobicContact CE1-CB 4.22Å; F52-A101 HydrophobicContact CE2-CB 3.75Å; F52-A101 HydrophobicContact CZ-CB 3.78Å; L97-A101 WeakPolarHBondContact O-CB 3.48Å; L97-A101 PolarHBondContact O-N 3.47Å; P98-A101 PolarHBondContact O-N 2.88Å; A101-L104 PolarHBondContact O-N 3.46Å; A101-A105 WeakPolarHBondContact O-CB 3.09Å; A101-A105 PolarHBondContact O-N 2.9Å
102	I	89.1	Confident	89.5	Confident	52 Å²	52	40.4 Å²	40.4	27%	0.267	23%	0.229	S	C	.	.	H	α-helix	trans	-67.5	-40.2	176.2	-68.7	163.3	0	0	0	111	F52 P98 F99 I100 L104 A105 L106 F111	F52-I102 HydrophobicContact CZ-CG1 4.29Å; P98-I102 WeakPolarHBondContact O-CB 3.27Å; P98-I102 WeakPolarHBondContact O-CD1 3.36Å; P98-I102 WeakPolarHBondContact O-CG1 3.22Å; P98-I102 PolarHBondContact O-N 3.46Å; F99-I102 PolarHBondContact O-N 2.92Å; I100-I102 VanDerWaalsContact C-N 3.33Å; I100-I102 PolarHBondContact O-N 3.29Å; I102-L104 VanDerWaalsContact C-N 3.28Å; I102-L104 PolarHBondContact O-N 3.43Å; I102-A105 PolarHBondContact O-N 3.42Å; I102-L106 HydrophobicContact CG2-CD1 3.5Å; I102-L106 HydrophobicContact CG2-CG 3.98Å; I102-L106 WeakPolarHBondContact O-CB 3.48Å; I102-L106 WeakPolarHBondContact O-CG 3.18Å; I102-L106 PolarHBondContact O-N 2.99Å; I102-F111 HydrophobicContact CB-CE2 4.16Å; I102-F111 HydrophobicContact CB-CZ 3.98Å; I102-F111 HydrophobicContact CD1-CZ 3.84Å; I102-F111 HydrophobicContact CG2-CE2 3.95Å; I102-F111 HydrophobicContact CG2-CZ 3.65Å
103	Q	86	Confident	89.4	Confident	8 Å²	8	40.1 Å²	40.1	4%	0.037	23%	0.232	C	C	.	.	H	α-helix	trans	-57.8	-43.4	173.2	-176.2	-177.8	18.1	0	0	111.6	F99 I100 V107 H108 W109 C193	F99-Q103 PolarHBondContact O-N 3.08Å; I100-Q103 WeakPolarHBondContact O-CB 3.47Å; I100-Q103 PolarHBondContact O-N 3.41Å; Q103-V107 VanDerWaalsContact O-CA 3.29Å; Q103-V107 WeakPolarHBondContact O-CA 3.48Å; Q103-V107 PolarHBondContact O-N 3.47Å; Q103-H108 WeakPolarHBondContact CA-O 3.25Å; Q103-H108 PolarHBondContact O-N 3.37Å; Q103-W109 HydrophobicContact CB-CE3 3.92Å; Q103-W109 HydrophobicContact CB-CZ3 4.38Å; Q103-W109 HydrophobicContact CG-CE3 4.13Å; Q103-C193 PolarHBondContact NE2-O 2.57Å; Q103-C193 VanDerWaalsContact NE2-O 3.08Å
104	L	83.3	Confident	89.5	Confident	29 Å²	29	45.2 Å²	45.2	15%	0.152	26%	0.264	C	S	.	.	H	α-helix	trans	-65.3	-41.6	177.6	-178.3	62.7	0	0	0	111.8	T44 I47 I100 A101 I102	T44-L104 HydrophobicContact CG2-CD1 4.07Å; T44-L104 HydrophobicContact CG2-CG 4Å; I47-L104 HydrophobicContact CB-CD2 3.94Å; I47-L104 HydrophobicContact CG2-CD2 3.43Å; I47-L104 VanDerWaalsContact CG2-CD2 3.43Å; I100-L104 PolarHBondContact O-N 2.86Å; A101-L104 PolarHBondContact O-N 3.46Å; I102-L104 VanDerWaalsContact C-N 3.28Å; I102-L104 PolarHBondContact O-N 3.43Å
105	A	84.4	Confident	89.5	Confident	55 Å²	55	47.6 Å²	47.6	46%	0.455	28%	0.276	S	S	.	.	H	α-helix	trans	-69.3	-41.2	-179.9	0	0	0	0	0	113	T48 A101 I102	T48-A105 HydrophobicContact CG2-CB 3.99Å; A101-A105 WeakPolarHBondContact O-CB 3.09Å; A101-A105 PolarHBondContact O-N 2.9Å; I102-A105 PolarHBondContact O-N 3.42Å
106	L	83.5	Confident	89.5	Confident	85 Å²	85	43.1 Å²	43.1	45%	0.445	25%	0.253	S	S	.	.	H	α-helix	trans	-87	-15	-178.1	-64.8	-178.9	0	0	0	112.9	I102 H108 P110	I102-L106 HydrophobicContact CG2-CD1 3.5Å; I102-L106 HydrophobicContact CG2-CG 3.98Å; I102-L106 WeakPolarHBondContact O-CB 3.48Å; I102-L106 WeakPolarHBondContact O-CG 3.18Å; I102-L106 PolarHBondContact O-N 2.99Å; L106-H108 PolarHBondContact O-CD2 3.09Å; L106-H108 PolarHBondContact O-N 2.88Å; L106-H108 VanDerWaalsContact O-N 3.15Å; L106-P110 HydrophobicContact CD1-CG 4.06Å
107	V	82.4	Confident	89.6	Confident	76 Å²	76	49 Å²	49	46%	0.461	27%	0.272	S	S	.	.	T	Hydrogen-bonded Turn	trans	56.1	27.1	-172.1	-161.4	0	0	0	0	111.5	Q103 F192	Q103-V107 VanDerWaalsContact O-CA 3.29Å; Q103-V107 WeakPolarHBondContact O-CA 3.48Å; Q103-V107 PolarHBondContact O-N 3.47Å; V107-F192 HydrophobicContact CG1-CE1 4.27Å; V107-F192 HydrophobicContact CG1-CZ 4.49Å; V107-F192 WeakPolarHBondContact O-CE1 3.43Å; V107-F192 WeakPolarHBondContact O-CZ 3.37Å
108	H	82.6	Confident	89.7	Confident	70 Å²	70	52.6 Å²	52.6	32%	0.324	29%	0.294	S	S	.	.	S	Bend	trans	-159.5	161.6	171.2	72.3	83.5	0	0	0	110.8	Q103 L106 P110 C191	Q103-H108 WeakPolarHBondContact CA-O 3.25Å; Q103-H108 PolarHBondContact O-N 3.37Å; L106-H108 PolarHBondContact O-CD2 3.09Å; L106-H108 PolarHBondContact O-N 2.88Å; L106-H108 VanDerWaalsContact O-N 3.15Å; H108-P110 VanDerWaalsContact O-CD 3.28Å; H108-P110 WeakPolarHBondContact O-CD 3.45Å; H108-C191 CarbonylContact C-O 3.55Å; H108-C191 VanDerWaalsContact CA-O 3.28Å; H108-C191 WeakPolarHBondContact CA-O 3.45Å
109	W	86.9	Confident	89.7	Confident	7 Å²	7	51.2 Å²	51.2	3%	0.027	29%	0.285	C	S	.	.			trans	-102.1	103.9	-180	-178.4	-95.1	0	0	0	110.9	F99 I100 Q103 F111 G112 L115 C116 V119 C191 C193	F99-W109 HydrophobicContact CB-CH2 3.75Å; F99-W109 HydrophobicContact CB-CZ3 4.03Å; I100-W109 HydrophobicContact CD1-CZ3 4.39Å; Q103-W109 HydrophobicContact CB-CE3 3.92Å; Q103-W109 HydrophobicContact CB-CZ3 4.38Å; Q103-W109 HydrophobicContact CG-CE3 4.13Å; W109-F111 AromaticContact CD2-CD2 3.91Å; W109-F111 HydrophobicContact CD2-CD2 3.91Å; W109-F111 AromaticContact CE2-CD2 3.76Å; W109-F111 AromaticContact CE3-CD2 3.98Å; W109-F111 HydrophobicContact CE3-CD2 3.98Å; W109-F111 AromaticContact CH2-CD2 3.8Å; W109-F111 HydrophobicContact CH2-CD2 3.8Å; W109-F111 HydrophobicContact CZ2-CB 3.74Å; W109-F111 AromaticContact CZ2-CD2 3.7Å; W109-F111 HydrophobicContact CZ2-CD2 3.7Å; W109-F111 HydrophobicContact CZ2-CG 4.16Å; W109-F111 AromaticContact CZ3-CD2 3.94Å; W109-F111 HydrophobicContact CZ3-CD2 3.94Å; W109-F111 HydrophobicContact CZ3-CE2 4.39Å; W109-G112 PolarHBondContact NE1-O 2.89Å; W109-L115 HydrophobicContact CZ2-CB 4.14Å; W109-L115 HydrophobicContact CZ2-CG 4.16Å; W109-C116 VanDerWaalsContact CZ2-CA 3.47Å; W109-C116 HydrophobicContact CZ2-CB 3.96Å; W109-V119 HydrophobicContact CH2-CB 4.23Å; W109-V119 HydrophobicContact CH2-CG1 4.47Å; W109-V119 HydrophobicContact CH2-CG2 4.14Å; W109-C191 PolarHBondContact N-O 3.23Å; W109-C193 HydrophobicContact CB-CB 4.16Å; W109-C193 HydrophobicContact CD2-CB 3.45Å; W109-C193 VanDerWaalsContact CD2-CB 3.45Å; W109-C193 HydrophobicContact CE3-CB 3.54Å; W109-C193 HydrophobicContact CG-CB 3.71Å; W109-C193 HydrophobicContact CZ3-CB 4.15Å
110	P	91.4	Very high	89.6	Confident	66 Å²	66	48.8 Å²	48.8	43%	0.429	28%	0.275	S	S	.	.			trans	-86.2	-8.6	-177.6	33.4	-36.4	0	0	0	114.5	L106 H108 G112	L106-P110 HydrophobicContact CD1-CG 4.06Å; H108-P110 VanDerWaalsContact O-CD 3.28Å; H108-P110 WeakPolarHBondContact O-CD 3.45Å; P110-G112 PolarHBondContact O-N 2.75Å
111	F	93.6	Very high	89.7	Confident	67 Å²	67	49.2 Å²	49.2	29%	0.294	28%	0.278	S	S	.	.	S	Bend	trans	-93.3	4.4	-164.3	-48.1	-76.3	0	0	0	115.5	F99 I102 W109 L115	F99-F111 HydrophobicContact CB-CD2 4.44Å; F99-F111 HydrophobicContact CB-CE2 4.18Å; F99-F111 AromaticContact CD1-CD1 4Å; F99-F111 HydrophobicContact CD1-CD1 4Å; F99-F111 AromaticContact CD1-CD2 3.95Å; F99-F111 HydrophobicContact CD1-CD2 3.95Å; F99-F111 AromaticContact CD1-CE1 3.85Å; F99-F111 HydrophobicContact CD1-CE1 3.85Å; F99-F111 AromaticContact CD1-CE2 3.8Å; F99-F111 HydrophobicContact CD1-CE2 3.8Å; F99-F111 HydrophobicContact CD1-CG 4.05Å; F99-F111 AromaticContact CD1-CZ 3.74Å; F99-F111 HydrophobicContact CD1-CZ 3.74Å; F99-F111 HydrophobicContact CE1-CD1 4.22Å; F99-F111 HydrophobicContact CE1-CE1 4.13Å; F99-F111 HydrophobicContact CE1-CZ 4.43Å; I102-F111 HydrophobicContact CB-CE2 4.16Å; I102-F111 HydrophobicContact CB-CZ 3.98Å; I102-F111 HydrophobicContact CD1-CZ 3.84Å; I102-F111 HydrophobicContact CG2-CE2 3.95Å; I102-F111 HydrophobicContact CG2-CZ 3.65Å; W109-F111 AromaticContact CD2-CD2 3.91Å; W109-F111 HydrophobicContact CD2-CD2 3.91Å; W109-F111 AromaticContact CE2-CD2 3.76Å; W109-F111 AromaticContact CE3-CD2 3.98Å; W109-F111 HydrophobicContact CE3-CD2 3.98Å; W109-F111 AromaticContact CH2-CD2 3.8Å; W109-F111 HydrophobicContact CH2-CD2 3.8Å; W109-F111 HydrophobicContact CZ2-CB 3.74Å; W109-F111 AromaticContact CZ2-CD2 3.7Å; W109-F111 HydrophobicContact CZ2-CD2 3.7Å; W109-F111 HydrophobicContact CZ2-CG 4.16Å; W109-F111 AromaticContact CZ3-CD2 3.94Å; W109-F111 HydrophobicContact CZ3-CD2 3.94Å; W109-F111 HydrophobicContact CZ3-CE2 4.39Å; F111-L115 HydrophobicContact CB-CB 4.02Å; F111-L115 HydrophobicContact CB-CD2 3.44Å; F111-L115 VanDerWaalsContact CB-CD2 3.44Å; F111-L115 HydrophobicContact CB-CG 4.2Å; F111-L115 HydrophobicContact CD1-CD2 4.12Å; F111-L115 HydrophobicContact CG-CD2 3.81Å
112	G	92.4	Very high	89.9	Confident	29 Å²	29	51 Å²	51	30%	0.299	29%	0.288	S	S	.	.	H	α-helix	trans	74.3	174.7	179.7	0	0	0	0	0	115.1	W109 P110 C116	W109-G112 PolarHBondContact NE1-O 2.89Å; P110-G112 PolarHBondContact O-N 2.75Å; G112-C116 PolarHBondContact O-N 3.27Å
113	P	92	Very high	89.9	Confident	78 Å²	78	50.1 Å²	50.1	51%	0.506	28%	0.284	S	S	.	.	H	α-helix	trans	-72.6	-32.7	-167.8	26.8	-34.8	0	0	0	114.4	C116 R117 V184	P113-C116 WeakPolarHBondContact O-CB 3.42Å; P113-C116 PolarHBondContact O-N 2.86Å; P113-R117 WeakPolarHBondContact O-CG 3.45Å; P113-R117 PolarHBondContact O-N 3.28Å; P113-R117 VanDerWaalsContact O-N 3.12Å; P113-V184 HydrophobicContact CB-CG2 4.26Å
114	V	95	Very high	90	Very high	113 Å²	113	50.2 Å²	50.2	69%	0.685	29%	0.286	S	S	*	.	H	α-helix	trans	-64.1	-49	-179.6	176.9	0	0	0	0	110.5	C116 R117 V118	V114-C116 VanDerWaalsContact C-N 3.3Å; V114-C116 PolarHBondContact O-N 2.94Å; V114-R117 PolarHBondContact O-N 2.96Å; V114-V118 WeakPolarHBondContact O-CG2 2.83Å; V114-V118 PolarHBondContact O-N 3.49Å; V114-V118 VanDerWaalsContact O-N 3.09Å
115	L	94.9	Very high	90.4	Very high	50 Å²	50	49.6 Å²	49.6	26%	0.262	28%	0.283	S	S	.	.	H	α-helix	trans	-68.2	-33.8	-179.4	-167.5	60.5	0	0	0	111.7	F99 W109 F111 R117 V118 V119	F99-L115 HydrophobicContact CD1-CD2 3.51Å; F99-L115 HydrophobicContact CD1-CG 4.46Å; F99-L115 HydrophobicContact CE1-CD2 3.38Å; F99-L115 HydrophobicContact CG-CD2 4.21Å; F99-L115 HydrophobicContact CZ-CD2 3.98Å; W109-L115 HydrophobicContact CZ2-CB 4.14Å; W109-L115 HydrophobicContact CZ2-CG 4.16Å; F111-L115 HydrophobicContact CB-CB 4.02Å; F111-L115 HydrophobicContact CB-CD2 3.44Å; F111-L115 VanDerWaalsContact CB-CD2 3.44Å; F111-L115 HydrophobicContact CB-CG 4.2Å; F111-L115 HydrophobicContact CD1-CD2 4.12Å; F111-L115 HydrophobicContact CG-CD2 3.81Å; L115-R117 PolarHBondContact O-N 2.74Å; L115-V118 PolarHBondContact O-N 2.97Å; L115-V119 HydrophobicContact CD1-CG2 4.14Å; L115-V119 HydrophobicContact CG-CG2 4.09Å; L115-V119 WeakPolarHBondContact O-CB 2.99Å; L115-V119 VanDerWaalsContact O-CG2 3.31Å; L115-V119 WeakPolarHBondContact O-CG2 3.46Å; L115-V119 PolarHBondContact O-N 3.45Å
116	C	92.9	Very high	90.7	Very high	0 Å²	0	47.3 Å²	47.3	0%	0	26%	0.263	C	S	.	.	H	α-helix	trans	-56.6	-50.9	173.4	171.8	0	0	0	0	111.2	W109 G112 P113 V114 V118 V119 M120 G183 V184 C193	W109-C116 VanDerWaalsContact CZ2-CA 3.47Å; W109-C116 HydrophobicContact CZ2-CB 3.96Å; G112-C116 PolarHBondContact O-N 3.27Å; P113-C116 WeakPolarHBondContact O-CB 3.42Å; P113-C116 PolarHBondContact O-N 2.86Å; V114-C116 VanDerWaalsContact C-N 3.3Å; V114-C116 PolarHBondContact O-N 2.94Å; C116-V118 VanDerWaalsContact C-N 3.34Å; C116-V118 PolarHBondContact O-N 2.96Å; C116-V119 PolarHBondContact O-N 3.48Å; C116-M120 WeakPolarHBondContact O-CB 3.46Å; C116-M120 VanDerWaalsContact O-CG 3.26Å; C116-M120 WeakPolarHBondContact O-CG 3.46Å; C116-M120 PolarHBondContact O-N 2.95Å; C116-G183 VanDerWaalsContact SG-C 3.58Å; C116-G183 PolarHBondContact SG-O 3.37Å; C116-V184 HydrophobicContact CB-CG2 3.77Å; C116-C193 WeakPolarHBondContact CA-SG 3.41Å; C116-C193 HydrophobicContact CB-CB 3.74Å; C116-C193 WeakPolarHBondContact CB-SG 3.22Å; C116-C193 WeakPolarHBondContact SG-CA 3.28Å; C116-C193 WeakPolarHBondContact SG-CB 3.47Å; C116-C193 CovalentContact SG-SG 2.03Å; C116-C193 PolarHBondContact SG-SG 2.87Å
117	R	94.2	Very high	91	Very high	133 Å²	133	44 Å²	44	50%	0.502	25%	0.245	S	C	.	.	H	α-helix	trans	-59.4	-44.1	177.6	-70.7	-176.7	-179.8	170.7	4.1	112.5	P113 V114 L115 T121 S182	P113-R117 WeakPolarHBondContact O-CG 3.45Å; P113-R117 PolarHBondContact O-N 3.28Å; P113-R117 VanDerWaalsContact O-N 3.12Å; V114-R117 PolarHBondContact O-N 2.96Å; L115-R117 PolarHBondContact O-N 2.74Å; R117-T121 WeakPolarHBondContact O-CB 3.48Å; R117-T121 PolarHBondContact O-N 3.29Å; R117-T121 PolarHBondContact O-OG1 3.49Å; R117-S182 WeakPolarHBondContact CA-OG 2.94Å; R117-S182 VanDerWaalsContact CG-O 3.31Å; R117-S182 WeakPolarHBondContact CG-O 3.31Å; R117-S182 PolarHBondContact NE-O 3.18Å
118	V	94.8	Very high	91.4	Very high	76 Å²	76	40.4 Å²	40.4	46%	0.461	22%	0.223	S	C	.	.	H	α-helix	trans	-62.3	-48.9	178.8	171.6	0	0	0	0	111	V114 L115 C116 T121 V122	V114-V118 WeakPolarHBondContact O-CG2 2.83Å; V114-V118 PolarHBondContact O-N 3.49Å; V114-V118 VanDerWaalsContact O-N 3.09Å; L115-V118 PolarHBondContact O-N 2.97Å; C116-V118 VanDerWaalsContact C-N 3.34Å; C116-V118 PolarHBondContact O-N 2.96Å; V118-T121 PolarHBondContact O-N 2.96Å; V118-V122 HydrophobicContact CG1-CG2 4.35Å; V118-V122 WeakPolarHBondContact O-CB 3.24Å; V118-V122 VanDerWaalsContact O-CG2 3.27Å; V118-V122 WeakPolarHBondContact O-CG2 3.27Å; V118-V122 PolarHBondContact O-N 2.92Å
119	V	93.4	Very high	91.9	Very high	5 Å²	5	37.1 Å²	37.1	3%	0.03	21%	0.208	C	C	.	.	H	α-helix	trans	-65.5	-48.2	-177.4	172.7	0	0	0	0	111	F99 I100 W109 L115 C116 T121 V122 D123	F99-V119 HydrophobicContact CB-CG1 4.46Å; F99-V119 HydrophobicContact CB-CG2 4.03Å; F99-V119 HydrophobicContact CD2-CG2 3.92Å; F99-V119 HydrophobicContact CG-CG2 4.1Å; I100-V119 HydrophobicContact CD1-CG1 3.51Å; I100-V119 HydrophobicContact CG1-CG1 3.74Å; W109-V119 HydrophobicContact CH2-CB 4.23Å; W109-V119 HydrophobicContact CH2-CG1 4.47Å; W109-V119 HydrophobicContact CH2-CG2 4.14Å; L115-V119 HydrophobicContact CD1-CG2 4.14Å; L115-V119 HydrophobicContact CG-CG2 4.09Å; L115-V119 WeakPolarHBondContact O-CB 2.99Å; L115-V119 VanDerWaalsContact O-CG2 3.31Å; L115-V119 WeakPolarHBondContact O-CG2 3.46Å; L115-V119 PolarHBondContact O-N 3.45Å; C116-V119 PolarHBondContact O-N 3.48Å; V119-T121 VanDerWaalsContact C-N 3.3Å; V119-T121 PolarHBondContact O-N 3Å; V119-V122 PolarHBondContact O-N 3.25Å; V119-D123 VanDerWaalsContact O-CB 3.24Å; V119-D123 WeakPolarHBondContact O-CB 3.42Å; V119-D123 PolarHBondContact O-N 3.44Å
120	M	90.4	Very high	92.1	Very high	12 Å²	12	36.9 Å²	36.9	6%	0.059	21%	0.207	C	C	.	.	H	α-helix	trans	-61.2	-40.4	176.9	-65.8	-61.8	-69.5	0	0	111.8	C116 S124 I178 C193 I195	C116-M120 WeakPolarHBondContact O-CB 3.46Å; C116-M120 VanDerWaalsContact O-CG 3.26Å; C116-M120 WeakPolarHBondContact O-CG 3.46Å; C116-M120 PolarHBondContact O-N 2.95Å; M120-S124 PolarHBondContact O-N 3.45Å; M120-S124 PolarHBondContact O-OG 2.87Å; M120-I178 HydrophobicContact CB-CG2 4.17Å; M120-C193 WeakPolarHBondContact CG-SG 3.35Å; M120-I195 HydrophobicContact CE-CD1 4.31Å; M120-I195 HydrophobicContact CE-CG1 3.78Å
121	T	91.7	Very high	92.1	Very high	22 Å²	22	33.8 Å²	33.8	14%	0.135	19%	0.187	C	C	.	.	H	α-helix	trans	-63.3	-49.9	176.5	-63.6	0	0	0	0	111.1	R117 V118 V119 L125 N175 V179	R117-T121 WeakPolarHBondContact O-CB 3.48Å; R117-T121 PolarHBondContact O-N 3.29Å; R117-T121 PolarHBondContact O-OG1 3.49Å; V118-T121 PolarHBondContact O-N 2.96Å; V119-T121 VanDerWaalsContact C-N 3.3Å; V119-T121 PolarHBondContact O-N 3Å; T121-L125 WeakPolarHBondContact O-CB 3.34Å; T121-L125 PolarHBondContact O-N 3.35Å; T121-N175 PolarHBondContact O-ND2 3.42Å; T121-V179 HydrophobicContact CG2-CG2 3.65Å
122	V	92.3	Very high	92.1	Very high	37 Å²	37	31.8 Å²	31.8	22%	0.224	18%	0.179	C	C	.	.	H	α-helix	trans	-66.4	-40.7	-176.7	167.7	0	0	0	0	111.5	L92 V118 V119 L125 N126	L92-V122 HydrophobicContact CB-CG1 4.4Å; L92-V122 VanDerWaalsContact O-CG1 3.27Å; L92-V122 WeakPolarHBondContact O-CG1 3.44Å; V118-V122 HydrophobicContact CG1-CG2 4.35Å; V118-V122 WeakPolarHBondContact O-CB 3.24Å; V118-V122 VanDerWaalsContact O-CG2 3.27Å; V118-V122 WeakPolarHBondContact O-CG2 3.27Å; V118-V122 PolarHBondContact O-N 2.92Å; V119-V122 PolarHBondContact O-N 3.25Å; V122-L125 PolarHBondContact O-N 3.48Å; V122-N126 PolarHBondContact O-N 3.19Å
123	D	89.2	Confident	92	Very high	35 Å²	35	30.4 Å²	30.4	19%	0.187	16%	0.164	C	C	.	.	H	α-helix	trans	-52.1	-58.1	173.7	174	71.9	0	0	0	111.4	F93 V119 N126 Y302	F93-D123 HydrophobicContact CE2-CB 4.33Å; F93-D123 WeakPolarHBondContact CE2-OD1 3.36Å; V119-D123 VanDerWaalsContact O-CB 3.24Å; V119-D123 WeakPolarHBondContact O-CB 3.42Å; V119-D123 PolarHBondContact O-N 3.44Å; D123-N126 PolarHBondContact O-N 2.93Å; D123-Y302 WeakPolarHBondContact OD1-CE1 3.3Å
124	S	89.3	Confident	91.9	Very high	10 Å²	10	26.9 Å²	26.9	7%	0.07	14%	0.141	C	C	.	.	H	α-helix	trans	-75.3	-28.1	-177.5	-57.7	0	0	0	0	113.7	M120 N126 Q127 F128 N175 I178	M120-S124 PolarHBondContact O-N 3.45Å; M120-S124 PolarHBondContact O-OG 2.87Å; S124-N126 VanDerWaalsContact C-N 3.26Å; S124-N126 PolarHBondContact O-N 3.16Å; S124-Q127 WeakPolarHBondContact O-CB 3.47Å; S124-Q127 PolarHBondContact O-N 2.91Å; S124-F128 VanDerWaalsContact O-CD2 3.23Å; S124-F128 WeakPolarHBondContact O-CD2 3.18Å; S124-N175 WeakPolarHBondContact CB-OD1 3.19Å; S124-I178 WeakPolarHBondContact OG-CD1 3.11Å
125	L	91.9	Very high	91.8	Very high	16 Å²	16	22.9 Å²	22.9	8%	0.084	12%	0.115	C	C	.	.	H	α-helix	trans	-63.6	-35.7	176.6	-177.7	64.6	0	0	0	111.6	T121 V122 F128 T129 W168 L172 N175	T121-L125 WeakPolarHBondContact O-CB 3.34Å; T121-L125 PolarHBondContact O-N 3.35Å; V122-L125 PolarHBondContact O-N 3.48Å; L125-F128 PolarHBondContact O-N 3.42Å; L125-T129 VanDerWaalsContact O-CB 3.29Å; L125-T129 WeakPolarHBondContact O-CB 3.22Å; L125-T129 PolarHBondContact O-N 3.24Å; L125-T129 PolarHBondContact O-OG1 3.14Å; L125-W168 HydrophobicContact CD2-CE3 4.13Å; L125-W168 HydrophobicContact CD2-CZ3 3.83Å; L125-W168 HydrophobicContact CG-CZ3 4.39Å; L125-L172 HydrophobicContact CD1-CB 4.44Å; L125-L172 HydrophobicContact CD1-CD2 3.8Å; L125-L172 HydrophobicContact CD1-CG 3.84Å; L125-L172 HydrophobicContact CD2-CD2 3.79Å; L125-L172 HydrophobicContact CD2-CG 4.33Å; L125-L172 HydrophobicContact CG-CD2 4.45Å; L125-N175 HydrophobicContact CD1-CB 4.42Å; L125-N175 PolarHBondContact N-ND2 2.88Å
126	N	90.8	Very high	91.7	Very high	7 Å²	7	21.7 Å²	21.7	4%	0.037	11%	0.11	C	C	.	.	H	α-helix	trans	-65.7	-39.2	179.4	-175.5	53.7	0	0	0	112.3	A89 F93 V122 D123 S124 F128 T129 S130 S305	A89-N126 PolarHBondContact O-OD1 3.11Å; F93-N126 HydrophobicContact CB-CB 3.59Å; F93-N126 VanDerWaalsContact CB-CG 3.45Å; F93-N126 HydrophobicContact CD1-CB 4.46Å; F93-N126 WeakPolarHBondContact CD1-ND2 3.4Å; F93-N126 HydrophobicContact CD2-CB 3.98Å; F93-N126 HydrophobicContact CG-CB 3.72Å; F93-N126 VanDerWaalsContact CG-ND2 3.3Å; F93-N126 WeakPolarHBondContact CG-ND2 3.41Å; V122-N126 PolarHBondContact O-N 3.19Å; D123-N126 PolarHBondContact O-N 2.93Å; S124-N126 VanDerWaalsContact C-N 3.26Å; S124-N126 PolarHBondContact O-N 3.16Å; N126-F128 PolarHBondContact O-N 3.23Å; N126-T129 PolarHBondContact O-N 3.47Å; N126-S130 WeakPolarHBondContact O-CB 3.34Å; N126-S130 PolarHBondContact O-N 3.21Å; N126-S130 PolarHBondContact O-OG 3.07Å; N126-S130 PolarHBondContact OD1-OG 2.84Å; N126-S305 PolarHBondContact ND2-OG 3.28Å
127	Q	88.6	Confident	91.4	Very high	15 Å²	15	22 Å²	22	7%	0.07	11%	0.111	C	C	.	.	H	α-helix	trans	-53.8	-53.3	175.3	176.9	-179.4	-5.8	0	0	111.2	S124 I131 W269 Y273	S124-Q127 WeakPolarHBondContact O-CB 3.47Å; S124-Q127 PolarHBondContact O-N 2.91Å; Q127-I131 WeakPolarHBondContact O-CG2 3.19Å; Q127-I131 PolarHBondContact O-N 3.42Å; Q127-W269 HydrophobicContact CB-CH2 3.68Å; Q127-W269 HydrophobicContact CB-CZ2 4.01Å; Q127-W269 HydrophobicContact CB-CZ3 4.32Å; Q127-W269 HydrophobicContact CG-CE3 4.22Å; Q127-W269 HydrophobicContact CG-CH2 3.5Å; Q127-W269 VanDerWaalsContact CG-CH2 3.5Å; Q127-W269 HydrophobicContact CG-CZ2 3.93Å; Q127-W269 HydrophobicContact CG-CZ3 3.66Å; Q127-Y273 PolarHBondContact NE2-OH 3.34Å
128	F	92.2	Very high	91.1	Very high	1 Å²	1	15.7 Å²	15.7	0%	0.004	9%	0.088	C	C	.	.	H	α-helix	trans	-68.4	-44.6	179.6	-63.4	-62.7	0	0	0	112.8	S124 L125 N126 S130 I131 F132 V174 N175 T212	S124-F128 VanDerWaalsContact O-CD2 3.23Å; S124-F128 WeakPolarHBondContact O-CD2 3.18Å; L125-F128 PolarHBondContact O-N 3.42Å; N126-F128 PolarHBondContact O-N 3.23Å; F128-S130 VanDerWaalsContact C-N 3.32Å; F128-S130 PolarHBondContact O-N 2.91Å; F128-I131 WeakPolarHBondContact O-CG2 3.39Å; F128-I131 PolarHBondContact O-N 3.13Å; F128-F132 HydrophobicContact CB-CD2 4.33Å; F128-F132 HydrophobicContact CB-CE2 3.99Å; F128-F132 HydrophobicContact CD1-CZ 4.37Å; F128-F132 VanDerWaalsContact O-CB 3.31Å; F128-F132 WeakPolarHBondContact O-CB 3.5Å; F128-F132 VanDerWaalsContact O-CD2 3.28Å; F128-F132 WeakPolarHBondContact O-CD2 3.24Å; F128-F132 WeakPolarHBondContact O-CG 3.46Å; F128-F132 PolarHBondContact O-N 3.2Å; F128-V174 HydrophobicContact CD1-CG1 3.64Å; F128-V174 HydrophobicContact CD2-CG1 4.01Å; F128-V174 HydrophobicContact CE1-CG1 3.46Å; F128-V174 VanDerWaalsContact CE1-CG1 3.46Å; F128-V174 HydrophobicContact CE2-CG1 3.85Å; F128-V174 HydrophobicContact CG-CG1 3.92Å; F128-V174 HydrophobicContact CZ-CG1 3.59Å; F128-N175 HydrophobicContact CD2-CB 4.4Å; F128-T212 HydrophobicContact CZ-CG2 3.86Å
129	T	92.6	Very high	91	Very high	0 Å²	0	14.9 Å²	14.9	0%	0	8%	0.08	C	C	.	.	H	α-helix	trans	-63.3	-41.4	-179	-57.8	0	0	0	0	111.4	A89 L125 N126 C133 V167 W168 S171	A89-T129 HydrophobicContact CB-CG2 3.92Å; L125-T129 VanDerWaalsContact O-CB 3.29Å; L125-T129 WeakPolarHBondContact O-CB 3.22Å; L125-T129 PolarHBondContact O-N 3.24Å; L125-T129 PolarHBondContact O-OG1 3.14Å; N126-T129 PolarHBondContact O-N 3.47Å; T129-C133 WeakPolarHBondContact O-CB 3.49Å; T129-C133 PolarHBondContact O-N 2.8Å; T129-V167 HydrophobicContact CG2-CG1 4.21Å; T129-W168 HydrophobicContact CG2-CD2 4.27Å; T129-W168 HydrophobicContact CG2-CH2 4.42Å; T129-W168 HydrophobicContact CG2-CZ2 4.19Å; T129-S171 WeakPolarHBondContact CA-OG 3.1Å; T129-S171 PolarHBondContact N-OG 3.07Å; T129-S171 WeakPolarHBondContact OG1-CB 3.11Å; T129-S171 PolarHBondContact OG1-OG 3.23Å
130	S	90.6	Very high	90.7	Very high	2 Å²	2	15.1 Å²	15.1	1%	0.014	8%	0.081	C	C	.	.	H	α-helix	trans	-61.6	-52.7	177.4	-71.1	0	0	0	0	111.6	L86 N126 F128 C133 L134	L86-S130 WeakPolarHBondContact CD1-OG 3.48Å; N126-S130 WeakPolarHBondContact O-CB 3.34Å; N126-S130 PolarHBondContact O-N 3.21Å; N126-S130 PolarHBondContact O-OG 3.07Å; N126-S130 PolarHBondContact OD1-OG 2.84Å; F128-S130 VanDerWaalsContact C-N 3.32Å; F128-S130 PolarHBondContact O-N 2.91Å; S130-C133 WeakPolarHBondContact O-CB 3.29Å; S130-C133 PolarHBondContact O-N 2.69Å; S130-L134 WeakPolarHBondContact O-CG 3.25Å; S130-L134 PolarHBondContact O-N 2.71Å
131	I	91.4	Very high	90.5	Very high	1 Å²	1	15.4 Å²	15.4	1%	0.005	8%	0.082	C	C	.	.	H	α-helix	trans	-69.5	-38	-176.2	-168.6	51.1	0	0	0	112.8	Q127 F128 C133 L134 M135 P220 I224 F265	Q127-I131 WeakPolarHBondContact O-CG2 3.19Å; Q127-I131 PolarHBondContact O-N 3.42Å; F128-I131 WeakPolarHBondContact O-CG2 3.39Å; F128-I131 PolarHBondContact O-N 3.13Å; I131-C133 VanDerWaalsContact C-N 3.33Å; I131-L134 HydrophobicContact CD1-CB 4.45Å; I131-L134 HydrophobicContact CD1-CD1 4.42Å; I131-L134 PolarHBondContact O-N 2.93Å; I131-M135 WeakPolarHBondContact O-CB 3.44Å; I131-M135 PolarHBondContact O-N 2.96Å; I131-P220 HydrophobicContact CD1-CB 3.95Å; I131-P220 HydrophobicContact CG1-CB 3.35Å; I131-P220 HydrophobicContact CG1-CG 3.82Å; I131-P220 HydrophobicContact CG2-CG 4.24Å; I131-I224 HydrophobicContact CD1-CD1 3.89Å; I131-F265 HydrophobicContact CB-CE1 4.37Å; I131-F265 HydrophobicContact CB-CE2 3.8Å; I131-F265 HydrophobicContact CB-CZ 3.62Å; I131-F265 HydrophobicContact CD1-CD1 3.63Å; I131-F265 HydrophobicContact CD1-CD2 4.17Å; I131-F265 HydrophobicContact CD1-CE1 3.32Å; I131-F265 HydrophobicContact CD1-CE2 3.9Å; I131-F265 HydrophobicContact CD1-CG 4.05Å; I131-F265 HydrophobicContact CD1-CZ 3.48Å; I131-F265 VanDerWaalsContact CD1-CZ 3.48Å; I131-F265 HydrophobicContact CG1-CE1 3.79Å; I131-F265 HydrophobicContact CG1-CE2 4.12Å; I131-F265 HydrophobicContact CG1-CZ 3.54Å
132	F	93.9	Very high	90.4	Very high	26 Å²	26	16.7 Å²	16.7	11%	0.114	9%	0.085	C	C	.	.	H	α-helix	trans	-66.3	-36.7	173.9	-65.5	-21.8	0	0	0	111.7	F128 M135 V136 V167 V170 S171 V174 L215 P220	F128-F132 HydrophobicContact CB-CD2 4.33Å; F128-F132 HydrophobicContact CB-CE2 3.99Å; F128-F132 HydrophobicContact CD1-CZ 4.37Å; F128-F132 VanDerWaalsContact O-CB 3.31Å; F128-F132 WeakPolarHBondContact O-CB 3.5Å; F128-F132 VanDerWaalsContact O-CD2 3.28Å; F128-F132 WeakPolarHBondContact O-CD2 3.24Å; F128-F132 WeakPolarHBondContact O-CG 3.46Å; F128-F132 PolarHBondContact O-N 3.2Å; F132-M135 HydrophobicContact CD1-CE 4.29Å; F132-M135 PolarHBondContact O-N 3.01Å; F132-V136 WeakPolarHBondContact O-CB 3.32Å; F132-V136 WeakPolarHBondContact O-CG2 3.18Å; F132-V136 PolarHBondContact O-N 3.42Å; F132-V167 HydrophobicContact CB-CG1 3.79Å; F132-V167 HydrophobicContact CB-CG2 4.4Å; F132-V170 HydrophobicContact CD2-CG1 4.24Å; F132-V170 HydrophobicContact CE2-CG1 3.79Å; F132-V170 HydrophobicContact CZ-CG1 4.42Å; F132-S171 WeakPolarHBondContact CD2-OG 3.12Å; F132-V174 HydrophobicContact CE2-CG2 4.42Å; F132-V174 HydrophobicContact CZ-CG2 4.43Å; F132-L215 WeakPolarHBondContact CE1-O 3.02Å; F132-P220 HydrophobicContact CD1-CG 4.27Å; F132-P220 HydrophobicContact CE1-CG 4.04Å
133	C	90.8	Very high	90.2	Very high	0 Å²	0	17.4 Å²	17.4	0%	0	9%	0.087	C	C	.	.	H	α-helix	trans	-62.3	-44.7	172.2	-168.5	0	0	0	0	111.3	L86 T129 S130 I131 M135 V136 M137	L86-C133 HydrophobicContact CD1-CB 4.35Å; T129-C133 WeakPolarHBondContact O-CB 3.49Å; T129-C133 PolarHBondContact O-N 2.8Å; S130-C133 WeakPolarHBondContact O-CB 3.29Å; S130-C133 PolarHBondContact O-N 2.69Å; I131-C133 VanDerWaalsContact C-N 3.33Å; C133-M135 VanDerWaalsContact C-N 3.35Å; C133-M135 PolarHBondContact O-N 3.33Å; C133-V136 PolarHBondContact O-N 3.05Å; C133-M137 WeakPolarHBondContact O-CB 3.48Å; C133-M137 VanDerWaalsContact O-CG 3.27Å; C133-M137 WeakPolarHBondContact O-CG 3.34Å; C133-M137 PolarHBondContact O-N 3.09Å
134	L	88.4	Confident	90	Very high	3 Å²	3	16 Å²	16	2%	0.016	8%	0.08	C	C	.	.	H	α-helix	trans	-62.8	-38.8	175.7	-67.4	-179.5	0	0	0	113	S130 I131 M137 S138 I224 V261 F265	S130-L134 WeakPolarHBondContact O-CG 3.25Å; S130-L134 PolarHBondContact O-N 2.71Å; I131-L134 HydrophobicContact CD1-CB 4.45Å; I131-L134 HydrophobicContact CD1-CD1 4.42Å; I131-L134 PolarHBondContact O-N 2.93Å; L134-M137 HydrophobicContact CD2-SD 4.47Å; L134-M137 PolarHBondContact O-N 3.34Å; L134-S138 WeakPolarHBondContact O-CB 3.23Å; L134-S138 PolarHBondContact O-N 3.27Å; L134-S138 PolarHBondContact O-OG 2.78Å; L134-I224 HydrophobicContact CB-CD1 4.36Å; L134-V261 HydrophobicContact CD1-CG1 4.05Å; L134-V261 HydrophobicContact CD2-CB 4.39Å; L134-V261 HydrophobicContact CD2-CG1 3.34Å; L134-V261 HydrophobicContact CG-CG1 4.34Å; L134-F265 HydrophobicContact CD1-CB 4.04Å; L134-F265 HydrophobicContact CD1-CD2 4.11Å; L134-F265 HydrophobicContact CD1-CG 4.18Å
135	M	93.1	Very high	89.8	Confident	30 Å²	30	16.7 Å²	16.7	15%	0.148	8%	0.084	C	C	.	.	H	α-helix	trans	-60.9	-50.9	173.9	-172.7	-152.5	-74.4	0	0	110.5	I131 F132 C133 M137 S138 I139 P220 V223 I224	I131-M135 WeakPolarHBondContact O-CB 3.44Å; I131-M135 PolarHBondContact O-N 2.96Å; F132-M135 HydrophobicContact CD1-CE 4.29Å; F132-M135 PolarHBondContact O-N 3.01Å; C133-M135 VanDerWaalsContact C-N 3.35Å; C133-M135 PolarHBondContact O-N 3.33Å; M135-M137 VanDerWaalsContact C-N 3.34Å; M135-M137 PolarHBondContact O-N 2.85Å; M135-S138 WeakPolarHBondContact O-CB 3.16Å; M135-S138 PolarHBondContact O-N 2.95Å; M135-S138 VanDerWaalsContact O-N 3.11Å; M135-I139 HydrophobicContact CG-CD1 4.1Å; M135-I139 WeakPolarHBondContact O-CG1 3.36Å; M135-I139 PolarHBondContact O-N 3.43Å; M135-I139 HydrophobicContact SD-CD1 4.29Å; M135-P220 VanDerWaalsContact CE-CA 3.41Å; M135-P220 HydrophobicContact CE-CB 3.69Å; M135-P220 HydrophobicContact CE-CG 3.87Å; M135-V223 HydrophobicContact CE-CB 4.38Å; M135-V223 HydrophobicContact CE-CG2 4.38Å; M135-V223 HydrophobicContact CG-CB 3.98Å; M135-V223 HydrophobicContact CG-CG1 3.59Å; M135-V223 HydrophobicContact SD-CB 4.24Å; M135-V223 HydrophobicContact SD-CG1 3.96Å; M135-V223 HydrophobicContact SD-CG2 4.44Å; M135-I224 HydrophobicContact CB-CD1 4.32Å; M135-I224 HydrophobicContact CB-CG1 4.19Å; M135-I224 HydrophobicContact CG-CG1 4.36Å
136	V	92.5	Very high	89.5	Confident	24 Å²	24	17 Å²	17	15%	0.145	9%	0.086	C	C	.	.	H	α-helix	trans	-60.7	-42.7	177.3	168	0	0	0	0	111.5	Y82 F132 C133 S138 I139 D140 I163 V167	Y82-V136 HydrophobicContact CD1-CG1 4.05Å; Y82-V136 HydrophobicContact CE1-CG1 3.35Å; Y82-V136 HydrophobicContact CE2-CG1 4.22Å; Y82-V136 VanDerWaalsContact CZ-CG1 3.44Å; Y82-V136 WeakPolarHBondContact OH-CG1 3.5Å; F132-V136 WeakPolarHBondContact O-CB 3.32Å; F132-V136 WeakPolarHBondContact O-CG2 3.18Å; F132-V136 PolarHBondContact O-N 3.42Å; C133-V136 PolarHBondContact O-N 3.05Å; V136-S138 VanDerWaalsContact C-N 3.28Å; V136-S138 PolarHBondContact O-N 3.46Å; V136-I139 PolarHBondContact O-N 2.86Å; V136-D140 WeakPolarHBondContact O-CB 3.47Å; V136-D140 PolarHBondContact O-N 3.21Å; V136-I163 HydrophobicContact CB-CG2 4.41Å; V136-I163 HydrophobicContact CG1-CG2 3.57Å; V136-I163 HydrophobicContact CG2-CG2 3.93Å; V136-V167 HydrophobicContact CG2-CG2 3.95Å
137	M	87.8	Confident	89.2	Confident	7 Å²	7	19.8 Å²	19.8	3%	0.034	10%	0.099	C	C	.	.	H	α-helix	trans	-59.6	-40.5	175	-74.9	-177.9	72	0	0	111.5	T79 Y82 I83 C133 L134 M135 D140 R141 V258	T79-M137 HydrophobicContact CG2-CE 4.48Å; Y82-M137 HydrophobicContact CD2-CG 4.2Å; Y82-M137 HydrophobicContact CG-CG 3.97Å; I83-M137 HydrophobicContact CG1-CE 4.14Å; C133-M137 WeakPolarHBondContact O-CB 3.48Å; C133-M137 VanDerWaalsContact O-CG 3.27Å; C133-M137 WeakPolarHBondContact O-CG 3.34Å; C133-M137 PolarHBondContact O-N 3.09Å; L134-M137 HydrophobicContact CD2-SD 4.47Å; L134-M137 PolarHBondContact O-N 3.34Å; M135-M137 VanDerWaalsContact C-N 3.34Å; M135-M137 PolarHBondContact O-N 2.85Å; M137-D140 PolarHBondContact O-N 3.49Å; M137-R141 WeakPolarHBondContact O-CG 3.23Å; M137-R141 PolarHBondContact O-N 3.43Å; M137-V258 HydrophobicContact CE-CG2 4.34Å
138	S	88.7	Confident	88.8	Confident	0 Å²	0	21.6 Å²	21.6	0%	0	11%	0.112	C	C	.	.	H	α-helix	trans	-69.5	-39.1	177.8	-58.6	0	0	0	0	112.2	L134 M135 V136 R141 Y142 Y228	L134-S138 WeakPolarHBondContact O-CB 3.23Å; L134-S138 PolarHBondContact O-N 3.27Å; L134-S138 PolarHBondContact O-OG 2.78Å; M135-S138 WeakPolarHBondContact O-CB 3.16Å; M135-S138 PolarHBondContact O-N 2.95Å; M135-S138 VanDerWaalsContact O-N 3.11Å; V136-S138 VanDerWaalsContact C-N 3.28Å; V136-S138 PolarHBondContact O-N 3.46Å; S138-R141 PolarHBondContact O-N 3.22Å; S138-Y142 PolarHBondContact O-N 2.88Å; S138-Y228 WeakPolarHBondContact OG-CE2 3.29Å; S138-Y228 PolarHBondContact OG-OH 3.25Å
139	I	91.5	Very high	88.4	Confident	59 Å²	59	28.7 Å²	28.7	30%	0.303	15%	0.148	S	C	.	.	H	α-helix	trans	-63.7	-45.7	173	-67	165.7	0	0	0	110.8	M135 V136 R141 Y142 L143 V223	M135-I139 HydrophobicContact CG-CD1 4.1Å; M135-I139 WeakPolarHBondContact O-CG1 3.36Å; M135-I139 PolarHBondContact O-N 3.43Å; M135-I139 HydrophobicContact SD-CD1 4.29Å; V136-I139 PolarHBondContact O-N 2.86Å; I139-R141 VanDerWaalsContact C-N 3.26Å; I139-R141 PolarHBondContact O-N 3.16Å; I139-Y142 WeakPolarHBondContact O-CB 3.37Å; I139-Y142 PolarHBondContact O-N 3.48Å; I139-Y142 VanDerWaalsContact O-N 3.15Å; I139-L143 HydrophobicContact CG2-CD1 4.15Å; I139-L143 HydrophobicContact CG2-CG 4.37Å; I139-L143 WeakPolarHBondContact O-CG 3.29Å; I139-L143 PolarHBondContact O-N 3.46Å; I139-V223 HydrophobicContact CD1-CG1 4.05Å; I139-V223 HydrophobicContact CG1-CG1 4.2Å
140	D	88.3	Confident	87.9	Confident	11 Å²	11	35.7 Å²	35.7	6%	0.059	18%	0.179	C	C	.	.	H	α-helix	trans	-57.9	-40.2	175.9	164.6	82.8	0	0	0	111.4	Y82 V136 M137 L143 A144 R155	Y82-D140 HydrophobicContact CE2-CB 4.31Å; V136-D140 WeakPolarHBondContact O-CB 3.47Å; V136-D140 PolarHBondContact O-N 3.21Å; M137-D140 PolarHBondContact O-N 3.49Å; D140-L143 PolarHBondContact O-N 3.41Å; D140-A144 WeakPolarHBondContact O-CB 3.35Å; D140-A144 PolarHBondContact O-N 2.99Å; D140-R155 WeakPolarHBondContact OD1-CD 3.34Å; D140-R155 WeakPolarHBondContact OD1-CG 3.42Å; D140-R155 IonicContact OD1-NE 3.05Å; D140-R155 PolarHBondContact OD1-NE 2.91Å; D140-R155 IonicContact OD2-NE 3.94Å
141	R	86.2	Confident	87.6	Confident	18 Å²	18	35.9 Å²	35.9	7%	0.068	18%	0.18	C	C	.	.	H	α-helix	trans	-66.1	-44.2	174	-71.9	-51.8	97.9	159.9	13.6	112.9	T79 M137 S138 I139 L143 A144 V145 I231 V254 V258	T79-R141 PolarHBondContact OG1-NH2 3.28Å; M137-R141 WeakPolarHBondContact O-CG 3.23Å; M137-R141 PolarHBondContact O-N 3.43Å; S138-R141 PolarHBondContact O-N 3.22Å; I139-R141 VanDerWaalsContact C-N 3.26Å; I139-R141 PolarHBondContact O-N 3.16Å; R141-L143 VanDerWaalsContact C-N 3.33Å; R141-L143 PolarHBondContact O-N 3.41Å; R141-A144 PolarHBondContact O-N 2.82Å; R141-V145 WeakPolarHBondContact O-CG2 3.46Å; R141-V145 PolarHBondContact O-N 2.95Å; R141-I231 HydrophobicContact CB-CD1 4.32Å; R141-V254 HydrophobicContact CG-CG1 4.42Å; R141-V258 HydrophobicContact CG-CG2 4.43Å
142	Y	88.9	Confident	87.2	Confident	49 Å²	49	40.7 Å²	40.7	19%	0.192	21%	0.209	C	C	.	.	H	α-helix	trans	-56.2	-49	174.7	162.8	-98.8	0	0	0	110.9	S138 I139 A144 V145 V146 H147 L230 I231	S138-Y142 PolarHBondContact O-N 2.88Å; I139-Y142 WeakPolarHBondContact O-CB 3.37Å; I139-Y142 PolarHBondContact O-N 3.48Å; I139-Y142 VanDerWaalsContact O-N 3.15Å; Y142-A144 PolarHBondContact O-N 3.42Å; Y142-V145 PolarHBondContact O-N 3.4Å; Y142-V146 HydrophobicContact CD2-CB 4.04Å; Y142-V146 HydrophobicContact CD2-CG2 3.53Å; Y142-V146 HydrophobicContact CE2-CB 3.73Å; Y142-V146 HydrophobicContact CE2-CG1 3.88Å; Y142-V146 HydrophobicContact CE2-CG2 3.54Å; Y142-V146 HydrophobicContact CG-CG2 4.46Å; Y142-V146 WeakPolarHBondContact O-CB 3.3Å; Y142-V146 WeakPolarHBondContact O-CG2 3.38Å; Y142-V146 PolarHBondContact O-N 3.47Å; Y142-H147 AromaticContact CE1-CD2 3.99Å; Y142-H147 AromaticContact CZ-CD2 3.95Å; Y142-H147 AromaticContact CZ-NE2 3.86Å; Y142-H147 PolarHBondContact OH-NE2 3.34Å; Y142-H147 VanDerWaalsContact OH-NE2 3.16Å; Y142-L230 HydrophobicContact CD2-CB 3.96Å; Y142-L230 HydrophobicContact CD2-CD1 4.35Å; Y142-L230 HydrophobicContact CE2-CB 3.68Å; Y142-L230 HydrophobicContact CE2-CD1 3.69Å; Y142-L230 HydrophobicContact CE2-CG 4.34Å; Y142-I231 HydrophobicContact CD2-CG1 4.38Å
143	L	88.7	Confident	86.8	Confident	51 Å²	51	47 Å²	47	27%	0.267	24%	0.237	S	C	.	.	H	α-helix	trans	-61.2	-43.6	178.5	-68.7	175.6	0	0	0	111.9	I139 D140 R141 V145 H147 S151	I139-L143 HydrophobicContact CG2-CD1 4.15Å; I139-L143 HydrophobicContact CG2-CG 4.37Å; I139-L143 WeakPolarHBondContact O-CG 3.29Å; I139-L143 PolarHBondContact O-N 3.46Å; D140-L143 PolarHBondContact O-N 3.41Å; R141-L143 VanDerWaalsContact C-N 3.33Å; R141-L143 PolarHBondContact O-N 3.41Å; L143-V145 VanDerWaalsContact C-N 3.35Å; L143-V145 PolarHBondContact O-N 3Å; L143-H147 CarbonylContact O-C 3.52Å; L143-H147 WeakPolarHBondContact O-CA 3.44Å; L143-H147 PolarHBondContact O-N 2.95Å; L143-S151 WeakPolarHBondContact O-CB 3.38Å
144	A	84.9	Confident	86.4	Confident	6 Å²	6	55.1 Å²	55.1	5%	0.05	27%	0.268	C	S	.	.	H	α-helix	trans	-62.9	-38.4	-179.9	0	0	0	0	0	113.2	D140 R141 Y142	D140-A144 WeakPolarHBondContact O-CB 3.35Å; D140-A144 PolarHBondContact O-N 2.99Å; R141-A144 PolarHBondContact O-N 2.82Å; Y142-A144 PolarHBondContact O-N 3.42Å
145	V	83.5	Confident	86.3	Confident	24 Å²	24	59 Å²	59	15%	0.145	28%	0.282	C	S	.	.	H	α-helix	trans	-88.5	-44.6	-175.6	176.9	0	0	0	0	112.1	R141 Y142 L143 I231 V235 E251	R141-V145 WeakPolarHBondContact O-CG2 3.46Å; R141-V145 PolarHBondContact O-N 2.95Å; Y142-V145 PolarHBondContact O-N 3.4Å; L143-V145 VanDerWaalsContact C-N 3.35Å; L143-V145 PolarHBondContact O-N 3Å; V145-I231 HydrophobicContact CG1-CG2 4.2Å; V145-V235 HydrophobicContact CG1-CG2 3.91Å; V145-E251 HydrophobicContact CG2-CB 4.44Å
146	V	85.5	Confident	86.1	Confident	22 Å²	22	63.1 Å²	63.1	13%	0.133	30%	0.299	C	S	.	.	H	α-helix	trans	-85	-33.8	-173.1	-175.8	0	0	0	0	111.9	Y142 P148 I231 K234	Y142-V146 HydrophobicContact CD2-CB 4.04Å; Y142-V146 HydrophobicContact CD2-CG2 3.53Å; Y142-V146 HydrophobicContact CE2-CB 3.73Å; Y142-V146 HydrophobicContact CE2-CG1 3.88Å; Y142-V146 HydrophobicContact CE2-CG2 3.54Å; Y142-V146 HydrophobicContact CG-CG2 4.46Å; Y142-V146 WeakPolarHBondContact O-CB 3.3Å; Y142-V146 WeakPolarHBondContact O-CG2 3.38Å; Y142-V146 PolarHBondContact O-N 3.47Å; V146-P148 VanDerWaalsContact C-CD 3.5Å; V146-I231 HydrophobicContact CG2-CG1 4.36Å; V146-K234 HydrophobicContact CB-CG 4.4Å; V146-K234 HydrophobicContact CG1-CB 4.47Å; V146-K234 HydrophobicContact CG1-CD 4.43Å; V146-K234 HydrophobicContact CG1-CG 4.21Å; V146-K234 HydrophobicContact CG2-CB 3.93Å; V146-K234 HydrophobicContact CG2-CG 4.13Å
147	H	85.4	Confident	85.8	Confident	67 Å²	67	64.9 Å²	64.9	31%	0.31	31%	0.311	S	S	.	.			trans	-128.7	59.2	-176	-61.6	-71.6	0	0	0	112.8	Y142 L143 I149 K150 S151	Y142-H147 AromaticContact CE1-CD2 3.99Å; Y142-H147 AromaticContact CZ-CD2 3.95Å; Y142-H147 AromaticContact CZ-NE2 3.86Å; Y142-H147 PolarHBondContact OH-NE2 3.34Å; Y142-H147 VanDerWaalsContact OH-NE2 3.16Å; L143-H147 CarbonylContact O-C 3.52Å; L143-H147 WeakPolarHBondContact O-CA 3.44Å; L143-H147 PolarHBondContact O-N 2.95Å; H147-I149 VanDerWaalsContact C-N 3.32Å; H147-I149 PolarHBondContact O-N 3.36Å; H147-I149 VanDerWaalsContact O-N 3.15Å; H147-K150 HydrophobicContact CB-CB 4.31Å; H147-K150 PolarHBondContact O-N 3.5Å; H147-S151 WeakPolarHBondContact O-CB 3.36Å; H147-S151 PolarHBondContact O-N 3.1Å
148	P	80.6	Confident	85.9	Confident	52 Å²	52	74.9 Å²	74.9	34%	0.338	35%	0.348	S	S	.	.	H	α-helix	trans	-57.7	-38	-167.6	21.8	-33.9	0	0	0	114	V146 S151 T152	V146-P148 VanDerWaalsContact C-CD 3.5Å; P148-S151 PolarHBondContact O-OG 2.9Å; P148-T152 PolarHBondContact O-OG1 3.27Å
149	I	82.6	Confident	86.1	Confident	151 Å²	151	77.2 Å²	77.2	77%	0.774	36%	0.36	S	S	*	.	H	α-helix	trans	-71.2	-45.9	-179.4	-58.6	172.3	0	0	0	111.3	H147 S151	H147-I149 VanDerWaalsContact C-N 3.32Å; H147-I149 PolarHBondContact O-N 3.36Å; H147-I149 VanDerWaalsContact O-N 3.15Å; I149-S151 VanDerWaalsContact C-N 3.31Å; I149-S151 PolarHBondContact O-N 3.41Å
150	K	83.2	Confident	86	Confident	147 Å²	147	74.4 Å²	74.4	64%	0.639	35%	0.346	S	S	*	.	H	α-helix	trans	-67.3	-34.8	177.6	-66.6	-177.2	179	179.5	0	111.1	H147 T152 K153	H147-K150 HydrophobicContact CB-CB 4.31Å; H147-K150 PolarHBondContact O-N 3.5Å; K150-T152 VanDerWaalsContact C-N 3.26Å; K150-T152 PolarHBondContact O-N 3.29Å; K150-K153 PolarHBondContact O-N 2.79Å; K150-K153 VanDerWaalsContact O-N 3.15Å
151	S	84.3	Confident	86.1	Confident	5 Å²	5	80.6 Å²	80.6	4%	0.035	37%	0.372	C	S	.	.	H	α-helix	trans	-59.3	-33.2	-177.9	83.2	0	0	0	0	113.4	L143 H147 P148 I149 K153 W154 R155	L143-S151 WeakPolarHBondContact O-CB 3.38Å; H147-S151 WeakPolarHBondContact O-CB 3.36Å; H147-S151 PolarHBondContact O-N 3.1Å; P148-S151 PolarHBondContact O-OG 2.9Å; I149-S151 VanDerWaalsContact C-N 3.31Å; I149-S151 PolarHBondContact O-N 3.41Å; S151-K153 PolarHBondContact O-N 2.88Å; S151-W154 PolarHBondContact O-N 3.05Å; S151-R155 WeakPolarHBondContact O-CB 3.41Å; S151-R155 WeakPolarHBondContact O-CG 3.17Å; S151-R155 PolarHBondContact O-N 2.96Å
152	T	82.3	Confident	86.5	Confident	102 Å²	102	84.3 Å²	84.3	63%	0.626	40%	0.397	S	S	*	.	H	α-helix	trans	-61.2	-29.2	179.5	-51	0	0	0	0	112.7	P148 K150	P148-T152 PolarHBondContact O-OG1 3.27Å; K150-T152 VanDerWaalsContact C-N 3.26Å; K150-T152 PolarHBondContact O-N 3.29Å
153	K	85.4	Confident	86.7	Confident	159 Å²	159	84.6 Å²	84.6	69%	0.691	40%	0.401	S	S	*	.	H	α-helix	trans	-71.5	-36.3	176.4	-64.9	-174	179.1	-175.7	0	112.2	K150 S151 K156 I159	K150-K153 PolarHBondContact O-N 2.79Å; K150-K153 VanDerWaalsContact O-N 3.15Å; S151-K153 PolarHBondContact O-N 2.88Å; K153-K156 WeakPolarHBondContact O-CE 3.42Å; K153-I159 WeakPolarHBondContact O-CD1 3.47Å
154	W	82.8	Confident	86.9	Confident	170 Å²	170	82.5 Å²	82.5	64%	0.644	39%	0.391	S	S	*	.	H	α-helix	trans	-92.2	-29.6	-173.9	-70.4	88.4	0	0	0	113.9	S151 K156 I159	S151-W154 PolarHBondContact O-N 3.05Å; W154-K156 PolarHBondContact O-N 2.77Å; W154-I159 HydrophobicContact CE3-CG2 4.38Å; W154-I159 WeakPolarHBondContact O-CD1 3.5Å
155	R	86	Confident	87.4	Confident	85 Å²	85	88.3 Å²	88.3	32%	0.321	42%	0.42	S	S	.	.			trans	-81.7	56.1	-178.9	-66.5	-178	72.8	-126.6	0.5	111.9	V78 D140 S151	V78-R155 HydrophobicContact CG2-CB 4.29Å; V78-R155 WeakPolarHBondContact CG2-O 3.49Å; D140-R155 WeakPolarHBondContact OD1-CD 3.34Å; D140-R155 WeakPolarHBondContact OD1-CG 3.42Å; D140-R155 IonicContact OD1-NE 3.05Å; D140-R155 PolarHBondContact OD1-NE 2.91Å; D140-R155 IonicContact OD2-NE 3.94Å; S151-R155 WeakPolarHBondContact O-CB 3.41Å; S151-R155 WeakPolarHBondContact O-CG 3.17Å; S151-R155 PolarHBondContact O-N 2.96Å
156	K	88.8	Confident	88	Confident	116 Å²	116	89.9 Å²	89.9	50%	0.504	44%	0.435	S	S	.	.			trans	-106.3	141.7	173.6	-63.7	-178.7	-178.5	179.8	0	110.1	K153 W154 R158 I159 A160	K153-K156 WeakPolarHBondContact O-CE 3.42Å; W154-K156 PolarHBondContact O-N 2.77Å; K156-R158 PolarHBondContact O-N 3.19Å; K156-R158 VanDerWaalsContact O-N 3.17Å; K156-I159 HydrophobicContact CB-CD1 4.12Å; K156-I159 HydrophobicContact CB-CG1 4.24Å; K156-I159 HydrophobicContact CD-CD1 4.33Å; K156-I159 HydrophobicContact CG-CD1 4.42Å; K156-I159 PolarHBondContact O-N 3.33Å; K156-I159 VanDerWaalsContact O-N 3.08Å; K156-A160 PolarHBondContact O-N 3.23Å
157	P	87.1	Confident	88.5	Confident	61 Å²	61	89.3 Å²	89.3	40%	0.396	43%	0.432	S	S	.	.	H	α-helix	trans	-52.9	-37.2	177.2	-31.3	37.4	0	0	0	114.6	I81 A160 K161	I81-P157 HydrophobicContact CD1-CB 3.76Å; P157-A160 PolarHBondContact O-N 3.22Å; P157-K161 WeakPolarHBondContact O-CG 2.98Å; P157-K161 PolarHBondContact O-N 2.96Å
158	R	89.5	Confident	88.9	Confident	218 Å²	218	88.8 Å²	88.8	82%	0.823	43%	0.427	S	S	*	.	H	α-helix	trans	-62.5	-46.2	177.5	-65.7	-175.3	-176.6	168.8	0.5	111.8	K156 K161 T162	K156-R158 PolarHBondContact O-N 3.19Å; K156-R158 VanDerWaalsContact O-N 3.17Å; R158-K161 PolarHBondContact O-N 3.43Å; R158-T162 PolarHBondContact O-N 3.37Å; R158-T162 VanDerWaalsContact O-N 3.09Å; R158-T162 PolarHBondContact O-OG1 3.42Å
159	I	91.8	Very high	89.7	Confident	48 Å²	48	88.2 Å²	88.2	25%	0.246	43%	0.431	C	S	.	.	H	α-helix	trans	-64.5	-44	178.4	-61.4	173.5	0	0	0	110	K153 W154 K156 K161 T162 I163	K153-I159 WeakPolarHBondContact O-CD1 3.47Å; W154-I159 HydrophobicContact CE3-CG2 4.38Å; W154-I159 WeakPolarHBondContact O-CD1 3.5Å; K156-I159 HydrophobicContact CB-CD1 4.12Å; K156-I159 HydrophobicContact CB-CG1 4.24Å; K156-I159 HydrophobicContact CD-CD1 4.33Å; K156-I159 HydrophobicContact CG-CD1 4.42Å; K156-I159 PolarHBondContact O-N 3.33Å; K156-I159 VanDerWaalsContact O-N 3.08Å; I159-K161 VanDerWaalsContact C-N 3.3Å; I159-K161 PolarHBondContact O-N 2.96Å; I159-T162 PolarHBondContact O-N 3.3Å; I159-T162 VanDerWaalsContact O-N 3.16Å; I159-I163 HydrophobicContact CG2-CD1 3.76Å; I159-I163 HydrophobicContact CG2-CG1 4.27Å; I159-I163 WeakPolarHBondContact O-CG1 3.35Å; I159-I163 PolarHBondContact O-N 2.94Å
160	A	90.1	Very high	90.3	Very high	1 Å²	1	84.3 Å²	84.3	1%	0.008	41%	0.414	C	S	.	.	H	α-helix	trans	-58.1	-41.6	176.4	0	0	0	0	0	112.1	V78 I81 K156 P157 I163 N164	V78-A160 HydrophobicContact CB-CB 4.45Å; V78-A160 HydrophobicContact CG1-CB 3.93Å; V78-A160 HydrophobicContact CG2-CB 4.3Å; I81-A160 HydrophobicContact CB-CB 4.45Å; I81-A160 HydrophobicContact CD1-CB 4.21Å; I81-A160 HydrophobicContact CG2-CB 4.22Å; K156-A160 PolarHBondContact O-N 3.23Å; P157-A160 PolarHBondContact O-N 3.22Å; A160-I163 PolarHBondContact O-N 3.4Å; A160-N164 PolarHBondContact O-N 3.19Å; A160-N164 PolarHBondContact O-ND2 3Å
161	K	90.6	Very high	90.9	Very high	140 Å²	140	77.3 Å²	77.3	61%	0.609	38%	0.384	S	S	*	.	H	α-helix	trans	-62.6	-45.3	174.9	-72.3	179.3	178.9	-168.7	0	112.2	I81 P157 R158 I159 I163 N164 L165	I81-K161 HydrophobicContact CG2-CG 4.38Å; P157-K161 WeakPolarHBondContact O-CG 2.98Å; P157-K161 PolarHBondContact O-N 2.96Å; R158-K161 PolarHBondContact O-N 3.43Å; I159-K161 VanDerWaalsContact C-N 3.3Å; I159-K161 PolarHBondContact O-N 2.96Å; K161-I163 VanDerWaalsContact C-N 3.35Å; K161-I163 PolarHBondContact O-N 3.06Å; K161-N164 PolarHBondContact O-N 2.96Å; K161-L165 PolarHBondContact O-N 2.96Å
162	T	94.1	Very high	91.4	Very high	96 Å²	96	80.7 Å²	80.7	59%	0.589	40%	0.401	S	S	*	.	H	α-helix	trans	-61.2	-42.9	176.3	-55.2	0	0	0	0	111.8	R158 I159 L165 A166	R158-T162 PolarHBondContact O-N 3.37Å; R158-T162 VanDerWaalsContact O-N 3.09Å; R158-T162 PolarHBondContact O-OG1 3.42Å; I159-T162 PolarHBondContact O-N 3.3Å; I159-T162 VanDerWaalsContact O-N 3.16Å; T162-L165 PolarHBondContact O-N 3.31Å; T162-A166 PolarHBondContact O-N 2.8Å
163	I	94.4	Very high	92.1	Very high	55 Å²	55	81.3 Å²	81.3	28%	0.282	40%	0.4	S	S	.	.	H	α-helix	trans	-62.6	-44.4	176.4	-67.3	168.4	0	0	0	110.7	Y82 V136 I159 A160 K161 L165 A166 V167	Y82-I163 HydrophobicContact CE1-CG2 4.22Å; V136-I163 HydrophobicContact CB-CG2 4.41Å; V136-I163 HydrophobicContact CG1-CG2 3.57Å; V136-I163 HydrophobicContact CG2-CG2 3.93Å; I159-I163 HydrophobicContact CG2-CD1 3.76Å; I159-I163 HydrophobicContact CG2-CG1 4.27Å; I159-I163 WeakPolarHBondContact O-CG1 3.35Å; I159-I163 PolarHBondContact O-N 2.94Å; A160-I163 PolarHBondContact O-N 3.4Å; K161-I163 VanDerWaalsContact C-N 3.35Å; K161-I163 PolarHBondContact O-N 3.06Å; I163-L165 VanDerWaalsContact C-N 3.34Å; I163-L165 PolarHBondContact O-N 3.19Å; I163-A166 WeakPolarHBondContact O-CB 3.42Å; I163-A166 PolarHBondContact O-N 3.36Å; I163-V167 HydrophobicContact CG2-CG2 4.47Å; I163-V167 WeakPolarHBondContact O-CG2 3.28Å; I163-V167 PolarHBondContact O-N 2.98Å
164	N	92.8	Very high	92.5	Very high	8 Å²	8	74.3 Å²	74.3	4%	0.043	37%	0.37	C	S	.	.	H	α-helix	trans	-62.2	-42.6	177.1	-78.8	-72	0	0	0	111.6	Y82 N85 A160 K161 A166 V167 W168	Y82-N164 WeakPolarHBondContact CD1-ND2 3.35Å; Y82-N164 WeakPolarHBondContact CD1-OD1 3.32Å; Y82-N164 WeakPolarHBondContact CE1-ND2 3.31Å; N85-N164 HydrophobicContact CB-CB 4.42Å; N85-N164 VanDerWaalsContact CB-OD1 3.25Å; N85-N164 WeakPolarHBondContact CB-OD1 3Å; N85-N164 VanDerWaalsContact CG-OD1 3.31Å; N85-N164 WeakPolarHBondContact ND2-CB 3.33Å; N85-N164 PolarHBondContact ND2-OD1 2.63Å; A160-N164 PolarHBondContact O-N 3.19Å; A160-N164 PolarHBondContact O-ND2 3Å; K161-N164 PolarHBondContact O-N 2.96Å; N164-A166 VanDerWaalsContact C-N 3.29Å; N164-A166 PolarHBondContact O-N 2.94Å; N164-V167 WeakPolarHBondContact O-CB 3.42Å; N164-V167 PolarHBondContact O-N 2.97Å; N164-V167 VanDerWaalsContact O-N 3.14Å; N164-W168 PolarHBondContact O-N 3.39Å
165	L	94.3	Very high	93	Very high	128 Å²	128	66.2 Å²	66.2	67%	0.67	34%	0.34	S	S	*	.	H	α-helix	trans	-60.3	-40.9	174.8	-175.6	63.9	0	0	0	111.8	K161 T162 I163 W168 G169	K161-L165 PolarHBondContact O-N 2.96Å; T162-L165 PolarHBondContact O-N 3.31Å; I163-L165 VanDerWaalsContact C-N 3.34Å; I163-L165 PolarHBondContact O-N 3.19Å; L165-W168 PolarHBondContact O-N 2.9Å; L165-G169 PolarHBondContact O-N 3.24Å
166	A	95.9	Very high	93.4	Very high	56 Å²	56	65.9 Å²	65.9	46%	0.463	34%	0.344	S	S	.	.	H	α-helix	trans	-64	-39.7	174.2	0	0	0	0	0	112	T162 I163 N164 W168 G169 V170	T162-A166 PolarHBondContact O-N 2.8Å; I163-A166 WeakPolarHBondContact O-CB 3.42Å; I163-A166 PolarHBondContact O-N 3.36Å; N164-A166 VanDerWaalsContact C-N 3.29Å; N164-A166 PolarHBondContact O-N 2.94Å; A166-W168 PolarHBondContact O-N 3.25Å; A166-G169 PolarHBondContact O-N 2.86Å; A166-V170 WeakPolarHBondContact O-CB 3.36Å; A166-V170 VanDerWaalsContact O-CG2 3.32Å; A166-V170 WeakPolarHBondContact O-CG2 3.48Å; A166-V170 PolarHBondContact O-N 3.41Å
167	V	95.6	Very high	93.5	Very high	11 Å²	11	62 Å²	62	7%	0.067	33%	0.33	C	S	.	.	H	α-helix	trans	-58	-48	173.8	167.4	0	0	0	0	110.5	T129 F132 V136 I163 N164 G169 V170 S171	T129-V167 HydrophobicContact CG2-CG1 4.21Å; F132-V167 HydrophobicContact CB-CG1 3.79Å; F132-V167 HydrophobicContact CB-CG2 4.4Å; V136-V167 HydrophobicContact CG2-CG2 3.95Å; I163-V167 HydrophobicContact CG2-CG2 4.47Å; I163-V167 WeakPolarHBondContact O-CG2 3.28Å; I163-V167 PolarHBondContact O-N 2.98Å; N164-V167 WeakPolarHBondContact O-CB 3.42Å; N164-V167 PolarHBondContact O-N 2.97Å; N164-V167 VanDerWaalsContact O-N 3.14Å; V167-G169 VanDerWaalsContact C-N 3.34Å; V167-G169 PolarHBondContact O-N 3.22Å; V167-V170 PolarHBondContact O-N 3.41Å; V167-S171 WeakPolarHBondContact O-CB 3.31Å; V167-S171 PolarHBondContact O-N 2.99Å; V167-S171 PolarHBondContact O-OG 3.33Å
168	W	95.4	Very high	93.7	Very high	55 Å²	55	59.2 Å²	59.2	21%	0.208	31%	0.312	C	S	.	.	H	α-helix	trans	-58.6	-44.9	175.5	-77.2	99.9	0	0	0	112.6	N85 A89 L92 L125 T129 N164 L165 A166 S171 L172	N85-W168 PolarHBondContact ND2-NE1 3.42Å; N85-W168 PolarHBondContact OD1-NE1 3.3Å; A89-W168 HydrophobicContact CB-CH2 3.86Å; A89-W168 HydrophobicContact CB-CZ2 3.94Å; L92-W168 HydrophobicContact CD1-CH2 3.88Å; L92-W168 HydrophobicContact CD1-CZ3 4.47Å; L125-W168 HydrophobicContact CD2-CE3 4.13Å; L125-W168 HydrophobicContact CD2-CZ3 3.83Å; L125-W168 HydrophobicContact CG-CZ3 4.39Å; T129-W168 HydrophobicContact CG2-CD2 4.27Å; T129-W168 HydrophobicContact CG2-CH2 4.42Å; T129-W168 HydrophobicContact CG2-CZ2 4.19Å; N164-W168 PolarHBondContact O-N 3.39Å; L165-W168 PolarHBondContact O-N 2.9Å; A166-W168 PolarHBondContact O-N 3.25Å; W168-S171 PolarHBondContact O-N 3.31Å; W168-L172 WeakPolarHBondContact O-CB 3.16Å; W168-L172 WeakPolarHBondContact O-CG 3.09Å; W168-L172 PolarHBondContact O-N 2.93Å
169	G	96.1	Very high	93.9	Very high	40 Å²	40	51.4 Å²	51.4	41%	0.412	29%	0.289	S	S	.	.	H	α-helix	trans	-62.2	-45	178.1	0	0	0	0	0	112.8	L165 A166 V167 L172 L173	L165-G169 PolarHBondContact O-N 3.24Å; A166-G169 PolarHBondContact O-N 2.86Å; V167-G169 VanDerWaalsContact C-N 3.34Å; V167-G169 PolarHBondContact O-N 3.22Å; G169-L172 PolarHBondContact O-N 2.95Å; G169-L173 WeakPolarHBondContact O-CB 3.34Å; G169-L173 PolarHBondContact O-N 3.36Å
170	V	95.9	Very high	93.9	Very high	69 Å²	69	54.2 Å²	54.2	42%	0.418	30%	0.303	S	S	.	.	H	α-helix	trans	-66.9	-42.1	177.4	174.6	0	0	0	0	110.9	F132 A166 V167 L172 L173 V174	F132-V170 HydrophobicContact CD2-CG1 4.24Å; F132-V170 HydrophobicContact CE2-CG1 3.79Å; F132-V170 HydrophobicContact CZ-CG1 4.42Å; A166-V170 WeakPolarHBondContact O-CB 3.36Å; A166-V170 VanDerWaalsContact O-CG2 3.32Å; A166-V170 WeakPolarHBondContact O-CG2 3.48Å; A166-V170 PolarHBondContact O-N 3.41Å; V167-V170 PolarHBondContact O-N 3.41Å; V170-L172 VanDerWaalsContact C-N 3.35Å; V170-L172 PolarHBondContact O-N 2.95Å; V170-L173 WeakPolarHBondContact O-CB 3.27Å; V170-L173 PolarHBondContact O-N 3.15Å; V170-V174 HydrophobicContact CG1-CG2 4.39Å; V170-V174 VanDerWaalsContact O-CG2 3.31Å; V170-V174 WeakPolarHBondContact O-CG2 3.47Å; V170-V174 PolarHBondContact O-N 2.88Å
171	S	96.1	Very high	94	Very high	0 Å²	0	57.5 Å²	57.5	0%	0	32%	0.316	C	S	.	.	H	α-helix	trans	-60.5	-44	175.1	-60.5	0	0	0	0	111.7	T129 F132 V167 W168 V174 N175	T129-S171 WeakPolarHBondContact CA-OG 3.1Å; T129-S171 PolarHBondContact N-OG 3.07Å; T129-S171 WeakPolarHBondContact OG1-CB 3.11Å; T129-S171 PolarHBondContact OG1-OG 3.23Å; F132-S171 WeakPolarHBondContact CD2-OG 3.12Å; V167-S171 WeakPolarHBondContact O-CB 3.31Å; V167-S171 PolarHBondContact O-N 2.99Å; V167-S171 PolarHBondContact O-OG 3.33Å; W168-S171 PolarHBondContact O-N 3.31Å; S171-V174 PolarHBondContact O-N 3.19Å; S171-N175 WeakPolarHBondContact O-CB 3.34Å; S171-N175 PolarHBondContact O-N 2.9Å
172	L	94.9	Very high	94	Very high	77 Å²	77	51 Å²	51	40%	0.403	29%	0.287	S	S	.	.	H	α-helix	trans	-63.3	-41.5	176.2	-77.7	167.5	0	0	0	111.9	L125 W168 G169 V170 V174 N175 L176	L125-L172 HydrophobicContact CD1-CB 4.44Å; L125-L172 HydrophobicContact CD1-CD2 3.8Å; L125-L172 HydrophobicContact CD1-CG 3.84Å; L125-L172 HydrophobicContact CD2-CD2 3.79Å; L125-L172 HydrophobicContact CD2-CG 4.33Å; L125-L172 HydrophobicContact CG-CD2 4.45Å; W168-L172 WeakPolarHBondContact O-CB 3.16Å; W168-L172 WeakPolarHBondContact O-CG 3.09Å; W168-L172 PolarHBondContact O-N 2.93Å; G169-L172 PolarHBondContact O-N 2.95Å; V170-L172 VanDerWaalsContact C-N 3.35Å; V170-L172 PolarHBondContact O-N 2.95Å; L172-V174 VanDerWaalsContact C-N 3.34Å; L172-N175 CarbonylContact O-C 3.57Å; L172-N175 PolarHBondContact O-N 3.06Å; L172-L176 PolarHBondContact O-N 2.83Å; L172-L176 VanDerWaalsContact O-N 3.14Å
173	L	95.5	Very high	93.8	Very high	115 Å²	115	46.8 Å²	46.8	60%	0.602	26%	0.264	S	S	*	.	H	α-helix	trans	-60.5	-45.4	176.1	178.9	63.4	0	0	0	111.3	G169 V170 N175 L176	G169-L173 WeakPolarHBondContact O-CB 3.34Å; G169-L173 PolarHBondContact O-N 3.36Å; V170-L173 WeakPolarHBondContact O-CB 3.27Å; V170-L173 PolarHBondContact O-N 3.15Å; L173-N175 VanDerWaalsContact C-N 3.26Å; L173-N175 PolarHBondContact O-N 3.4Å; L173-L176 HydrophobicContact CD1-CD1 3.74Å; L173-L176 WeakPolarHBondContact O-CB 3.41Å; L173-L176 WeakPolarHBondContact O-CG 3.5Å; L173-L176 PolarHBondContact O-N 2.98Å
174	V	94.4	Very high	93.5	Very high	11 Å²	11	46.4 Å²	46.4	7%	0.067	26%	0.264	C	S	.	.	H	α-helix	trans	-67	-31.9	177.8	171.2	0	0	0	0	111.5	F128 F132 V170 S171 L172 L176 P177 Y211 L215	F128-V174 HydrophobicContact CD1-CG1 3.64Å; F128-V174 HydrophobicContact CD2-CG1 4.01Å; F128-V174 HydrophobicContact CE1-CG1 3.46Å; F128-V174 VanDerWaalsContact CE1-CG1 3.46Å; F128-V174 HydrophobicContact CE2-CG1 3.85Å; F128-V174 HydrophobicContact CG-CG1 3.92Å; F128-V174 HydrophobicContact CZ-CG1 3.59Å; F132-V174 HydrophobicContact CE2-CG2 4.42Å; F132-V174 HydrophobicContact CZ-CG2 4.43Å; V170-V174 HydrophobicContact CG1-CG2 4.39Å; V170-V174 VanDerWaalsContact O-CG2 3.31Å; V170-V174 WeakPolarHBondContact O-CG2 3.47Å; V170-V174 PolarHBondContact O-N 2.88Å; S171-V174 PolarHBondContact O-N 3.19Å; L172-V174 VanDerWaalsContact C-N 3.34Å; V174-L176 VanDerWaalsContact C-N 3.32Å; V174-L176 PolarHBondContact O-N 3.01Å; V174-P177 WeakPolarHBondContact O-CD 3.19Å; V174-Y211 WeakPolarHBondContact CA-OH 3.41Å; V174-Y211 HydrophobicContact CG1-CE1 3.99Å; V174-Y211 WeakPolarHBondContact CG1-OH 3.31Å; V174-Y211 PolarHBondContact O-OH 2.68Å; V174-Y211 VanDerWaalsContact O-OH 3.07Å; V174-L215 HydrophobicContact CG1-CB 4.48Å; V174-L215 HydrophobicContact CG1-CD1 4.13Å; V174-L215 HydrophobicContact CG2-CD1 4.13Å
175	N	93.8	Very high	93.2	Very high	0 Å²	0	47.9 Å²	47.9	0%	0	27%	0.271	C	S	.	.	T	Hydrogen-bonded Turn	trans	-83.8	-1.5	-178.9	-154.3	39.5	0	0	0	114.3	T121 S124 L125 F128 S171 L172 L173 P177 I178 V179	T121-N175 PolarHBondContact O-ND2 3.42Å; S124-N175 WeakPolarHBondContact CB-OD1 3.19Å; L125-N175 HydrophobicContact CD1-CB 4.42Å; L125-N175 PolarHBondContact N-ND2 2.88Å; F128-N175 HydrophobicContact CD2-CB 4.4Å; S171-N175 WeakPolarHBondContact O-CB 3.34Å; S171-N175 PolarHBondContact O-N 2.9Å; L172-N175 CarbonylContact O-C 3.57Å; L172-N175 PolarHBondContact O-N 3.06Å; L173-N175 VanDerWaalsContact C-N 3.26Å; L173-N175 PolarHBondContact O-N 3.4Å; N175-P177 VanDerWaalsContact C-CD 3.43Å; N175-I178 PolarHBondContact O-N 3.49Å; N175-I178 WeakPolarHBondContact OD1-CD1 3.17Å; N175-V179 PolarHBondContact O-N 3.34Å
176	L	94	Very high	92.7	Very high	79 Å²	79	47.2 Å²	47.2	41%	0.414	27%	0.273	S	S	.	.	H	α-helix	trans	-53.4	-41.5	-177.3	-75.6	-178.6	0	0	0	114.6	L172 L173 V174 I178 V179 I180	L172-L176 PolarHBondContact O-N 2.83Å; L172-L176 VanDerWaalsContact O-N 3.14Å; L173-L176 HydrophobicContact CD1-CD1 3.74Å; L173-L176 WeakPolarHBondContact O-CB 3.41Å; L173-L176 WeakPolarHBondContact O-CG 3.5Å; L173-L176 PolarHBondContact O-N 2.98Å; V174-L176 VanDerWaalsContact C-N 3.32Å; V174-L176 PolarHBondContact O-N 3.01Å; L176-I178 PolarHBondContact O-N 3.19Å; L176-V179 WeakPolarHBondContact O-CB 3.16Å; L176-V179 PolarHBondContact O-N 3.28Å; L176-V179 VanDerWaalsContact O-N 3.13Å; L176-I180 VanDerWaalsContact O-CG1 3.3Å; L176-I180 WeakPolarHBondContact O-CG1 3.49Å; L176-I180 PolarHBondContact O-N 2.98Å
177	P	91.9	Very high	91.8	Very high	33 Å²	33	47.8 Å²	47.8	21%	0.214	27%	0.265	C	S	.	.	H	α-helix	trans	-56.5	-38.5	177.6	-26.2	36	0	0	0	112.5	V174 N175 I180 Y181 F208	V174-P177 WeakPolarHBondContact O-CD 3.19Å; N175-P177 VanDerWaalsContact C-CD 3.43Å; P177-I180 PolarHBondContact O-N 2.86Å; P177-Y181 HydrophobicContact CB-CD2 4.29Å; P177-Y181 VanDerWaalsContact O-CB 3.31Å; P177-Y181 WeakPolarHBondContact O-CB 3.45Å; P177-Y181 WeakPolarHBondContact O-CD2 3.28Å; P177-Y181 PolarHBondContact O-N 3.15Å; P177-F208 HydrophobicContact CB-CD2 4.16Å; P177-F208 HydrophobicContact CB-CE2 4.19Å
178	I	91.2	Very high	90.7	Very high	3 Å²	3	56.5 Å²	56.5	2%	0.015	30%	0.304	C	S	.	.	H	α-helix	trans	-71.9	-39.5	179	-63.6	167.8	0	0	0	110.8	M120 S124 N175 L176 I180 S182 I195 F208	M120-I178 HydrophobicContact CB-CG2 4.17Å; S124-I178 WeakPolarHBondContact OG-CD1 3.11Å; N175-I178 PolarHBondContact O-N 3.49Å; N175-I178 WeakPolarHBondContact OD1-CD1 3.17Å; L176-I178 PolarHBondContact O-N 3.19Å; I178-I180 PolarHBondContact O-N 3.04Å; I178-S182 WeakPolarHBondContact O-CB 3.3Å; I178-S182 PolarHBondContact O-N 3.48Å; I178-S182 PolarHBondContact O-OG 3.23Å; I178-I195 HydrophobicContact CG1-CD1 4.25Å; I178-F208 HydrophobicContact CD1-CE2 4.01Å; I178-F208 HydrophobicContact CD1-CZ 3.46Å; I178-F208 VanDerWaalsContact CD1-CZ 3.46Å; I178-F208 HydrophobicContact CG1-CE2 3.81Å; I178-F208 HydrophobicContact CG1-CZ 3.55Å
179	V	92.5	Very high	89.5	Confident	55 Å²	55	60.6 Å²	60.6	33%	0.333	33%	0.33	S	S	.	.	H	α-helix	trans	-58.8	-39.7	175.2	178.7	0	0	0	0	111.2	T121 N175 L176	T121-V179 HydrophobicContact CG2-CG2 3.65Å; N175-V179 PolarHBondContact O-N 3.34Å; L176-V179 WeakPolarHBondContact O-CB 3.16Å; L176-V179 PolarHBondContact O-N 3.28Å; L176-V179 VanDerWaalsContact O-N 3.13Å
180	I	93.1	Very high	88.5	Confident	106 Å²	106	59.7 Å²	59.7	54%	0.544	32%	0.321	S	S	.	.	H	α-helix	trans	-78.5	-46.4	-177	-64.9	165.9	0	0	0	111.3	L176 P177 I178	L176-I180 VanDerWaalsContact O-CG1 3.3Å; L176-I180 WeakPolarHBondContact O-CG1 3.49Å; L176-I180 PolarHBondContact O-N 2.98Å; P177-I180 PolarHBondContact O-N 2.86Å; I178-I180 PolarHBondContact O-N 3.04Å
181	Y	91.1	Very high	88	Confident	71 Å²	71	58.5 Å²	58.5	28%	0.278	32%	0.315	S	S	.	.	H	α-helix	trans	-96.9	-8.7	-169.2	-62.1	-56.7	0	0	0	114.4	P177 V196 W197 P198	P177-Y181 HydrophobicContact CB-CD2 4.29Å; P177-Y181 VanDerWaalsContact O-CB 3.31Å; P177-Y181 WeakPolarHBondContact O-CB 3.45Å; P177-Y181 WeakPolarHBondContact O-CD2 3.28Å; P177-Y181 PolarHBondContact O-N 3.15Å; Y181-V196 PolarHBondContact O-N 3.3Å; Y181-W197 HydrophobicContact CD2-CE3 4.06Å; Y181-W197 AromaticContact CD2-CZ3 3.79Å; Y181-W197 HydrophobicContact CD2-CZ3 3.79Å; Y181-W197 HydrophobicContact CE2-CZ3 4.47Å; Y181-W197 HydrophobicContact CG-CE3 4.38Å; Y181-W197 HydrophobicContact CG-CZ3 4.42Å; Y181-P198 HydrophobicContact CD1-CG 3.97Å; Y181-P198 HydrophobicContact CE1-CG 3.3Å; Y181-P198 HydrophobicContact CE2-CG 4.46Å
182	S	90.1	Very high	87.5	Confident	2 Å²	2	59.3 Å²	59.3	1%	0.014	32%	0.319	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-66.9	137	172.3	56	0	0	0	0	111.6	R117 I178	R117-S182 WeakPolarHBondContact CA-OG 2.94Å; R117-S182 VanDerWaalsContact CG-O 3.31Å; R117-S182 WeakPolarHBondContact CG-O 3.31Å; R117-S182 PolarHBondContact NE-O 3.18Å; I178-S182 WeakPolarHBondContact O-CB 3.3Å; I178-S182 PolarHBondContact O-N 3.48Å; I178-S182 PolarHBondContact O-OG 3.23Å
183	G	89.7	Confident	87.1	Confident	9 Å²	9	56 Å²	56	9%	0.093	30%	0.302	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-169.7	179.4	-174.1	0	0	0	0	0	113.3	C116 C193 T194	C116-G183 VanDerWaalsContact SG-C 3.58Å; C116-G183 PolarHBondContact SG-O 3.37Å; G183-C193 WeakPolarHBondContact O-CA 3.19Å; G183-T194 PolarHBondContact N-O 3.33Å; G183-T194 PolarHBondContact O-N 3.43Å
184	V	89.1	Confident	86.7	Confident	46 Å²	46	51.1 Å²	51.1	28%	0.279	28%	0.277	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-107.2	127.1	176.7	176.4	0	0	0	0	108.4	P113 C116 C191 F192	P113-V184 HydrophobicContact CB-CG2 4.26Å; C116-V184 HydrophobicContact CB-CG2 3.77Å; V184-C191 HydrophobicContact CG1-CB 3.72Å; V184-F192 CarbonylContact C-O 3.43Å; V184-F192 VanDerWaalsContact CA-O 3.26Å; V184-F192 WeakPolarHBondContact CA-O 3.25Å
185	I	86.4	Confident	86.3	Confident	40 Å²	40	51.8 Å²	51.8	21%	0.205	28%	0.28	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-105.9	139.8	171.6	64.4	173.2	0	0	0	109.6	K187 C191 F192 T194 V196	I185-K187 HydrophobicContact CD1-CD 4.44Å; I185-K187 HydrophobicContact CD1-CG 4.49Å; I185-C191 CarbonylContact O-C 3.26Å; I185-C191 WeakPolarHBondContact O-CA 3.47Å; I185-F192 HydrophobicContact CG1-CB 4.01Å; I185-F192 PolarHBondContact N-O 3.18Å; I185-F192 PolarHBondContact O-N 3.44Å; I185-T194 HydrophobicContact CD1-CG2 3.66Å; I185-T194 HydrophobicContact CG1-CG2 3.84Å; I185-T194 HydrophobicContact CG2-CG2 4.08Å; I185-V196 HydrophobicContact CG2-CG2 3.54Å
186	T	83.8	Confident	86	Confident	114 Å²	114	54.8 Å²	54.8	70%	0.699	30%	0.298	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-100.6	119.7	175.1	-56	0	0	0	0	108.7
187	K	78	Confident	85.6	Confident	67 Å²	67	52.3 Å²	52.3	29%	0.291	28%	0.283	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-112	169	170.8	-67.3	-173.7	-179.4	179.2	0	109.2	D20 Q24 I185 N189 G190 F192	D20-K187 IonicContact OD2-NZ 2.7Å; D20-K187 PolarHBondContact OD2-NZ 3.3Å; Q24-K187 VanDerWaalsContact OE1-CD 3.32Å; I185-K187 HydrophobicContact CD1-CD 4.44Å; I185-K187 HydrophobicContact CD1-CG 4.49Å; K187-N189 PolarHBondContact O-N 3.2Å; K187-G190 PolarHBondContact N-O 3.41Å; K187-G190 PolarHBondContact O-N 2.9Å; K187-G190 VanDerWaalsContact O-O 3.11Å; K187-F192 HydrophobicContact CB-CD2 4.34Å; K187-F192 HydrophobicContact CB-CE2 4.16Å; K187-F192 HydrophobicContact CD-CD2 4.49Å; K187-F192 HydrophobicContact CG-CD2 4.47Å
188	H	70.9	Confident	85.5	Confident	195 Å²	195	52.4 Å²	52.4	90%	0.903	28%	0.284	S	S	*	.	T	Hydrogen-bonded Turn	trans	-55.1	-23.1	-174.4	-136	-64.5	0	0	0	114.4
189	N	71	Confident	85.2	Confident	140 Å²	140	60.4 Å²	60.4	75%	0.749	32%	0.321	S	S	*	.	T	Hydrogen-bonded Turn	trans	-111.3	9	-176.8	-65.3	-4.9	0	0	0	114.2	K187	K187-N189 PolarHBondContact O-N 3.2Å
190	G	75.3	Confident	85	Confident	21 Å²	21	61.7 Å²	61.7	22%	0.216	33%	0.331	C	S	.	.	E	Extended strand (participates in β ladder)	trans	146.2	175.2	177.6	0	0	0	0	0	114.8	K187 F192	K187-G190 PolarHBondContact N-O 3.41Å; K187-G190 PolarHBondContact O-N 2.9Å; K187-G190 VanDerWaalsContact O-O 3.11Å; G190-F192 WeakPolarHBondContact O-CD2 3.06Å; G190-F192 VanDerWaalsContact O-CE2 3.3Å; G190-F192 WeakPolarHBondContact O-CE2 3.37Å
191	C	84.9	Confident	84.4	Confident	45 Å²	45	60 Å²	60	30%	0.304	32%	0.321	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-89.5	140.4	172.8	-65.7	0	0	0	0	110	H108 W109 V184 I185	H108-C191 CarbonylContact C-O 3.55Å; H108-C191 VanDerWaalsContact CA-O 3.28Å; H108-C191 WeakPolarHBondContact CA-O 3.45Å; W109-C191 PolarHBondContact N-O 3.23Å; V184-C191 HydrophobicContact CG1-CB 3.72Å; I185-C191 CarbonylContact O-C 3.26Å; I185-C191 WeakPolarHBondContact O-CA 3.47Å
192	F	84.9	Confident	83.9	Confident	17 Å²	17	59.4 Å²	59.4	8%	0.075	32%	0.32	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-128.7	132.4	179.6	-63.3	-92.2	0	0	0	110	V107 V184 I185 K187 G190	V107-F192 HydrophobicContact CG1-CE1 4.27Å; V107-F192 HydrophobicContact CG1-CZ 4.49Å; V107-F192 WeakPolarHBondContact O-CE1 3.43Å; V107-F192 WeakPolarHBondContact O-CZ 3.37Å; V184-F192 CarbonylContact C-O 3.43Å; V184-F192 VanDerWaalsContact CA-O 3.26Å; V184-F192 WeakPolarHBondContact CA-O 3.25Å; I185-F192 HydrophobicContact CG1-CB 4.01Å; I185-F192 PolarHBondContact N-O 3.18Å; I185-F192 PolarHBondContact O-N 3.44Å; K187-F192 HydrophobicContact CB-CD2 4.34Å; K187-F192 HydrophobicContact CB-CE2 4.16Å; K187-F192 HydrophobicContact CD-CD2 4.49Å; K187-F192 HydrophobicContact CG-CD2 4.47Å; G190-F192 WeakPolarHBondContact O-CD2 3.06Å; G190-F192 VanDerWaalsContact O-CE2 3.3Å; G190-F192 WeakPolarHBondContact O-CE2 3.37Å
193	C	88.3	Confident	83.7	Confident	7 Å²	7	63 Å²	63	5%	0.047	34%	0.343	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-80.4	122.7	167.2	179.5	0	0	0	0	109	Q103 W109 C116 M120 G183	Q103-C193 PolarHBondContact NE2-O 2.57Å; Q103-C193 VanDerWaalsContact NE2-O 3.08Å; W109-C193 HydrophobicContact CB-CB 4.16Å; W109-C193 HydrophobicContact CD2-CB 3.45Å; W109-C193 VanDerWaalsContact CD2-CB 3.45Å; W109-C193 HydrophobicContact CE3-CB 3.54Å; W109-C193 HydrophobicContact CG-CB 3.71Å; W109-C193 HydrophobicContact CZ3-CB 4.15Å; C116-C193 WeakPolarHBondContact CA-SG 3.41Å; C116-C193 HydrophobicContact CB-CB 3.74Å; C116-C193 WeakPolarHBondContact CB-SG 3.22Å; C116-C193 WeakPolarHBondContact SG-CA 3.28Å; C116-C193 WeakPolarHBondContact SG-CB 3.47Å; C116-C193 CovalentContact SG-SG 2.03Å; C116-C193 PolarHBondContact SG-SG 2.87Å; M120-C193 WeakPolarHBondContact CG-SG 3.35Å; G183-C193 WeakPolarHBondContact O-CA 3.19Å
194	T	85.8	Confident	83.6	Confident	13 Å²	13	67.2 Å²	67.2	8%	0.08	36%	0.356	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-157.3	-179.8	-179.5	-168.2	0	0	0	0	110.7	G183 I185 V196	G183-T194 PolarHBondContact N-O 3.33Å; G183-T194 PolarHBondContact O-N 3.43Å; I185-T194 HydrophobicContact CD1-CG2 3.66Å; I185-T194 HydrophobicContact CG1-CG2 3.84Å; I185-T194 HydrophobicContact CG2-CG2 4.08Å; T194-V196 HydrophobicContact CG2-CG2 4.48Å
195	I	86.1	Confident	83.3	Confident	25 Å²	25	66.6 Å²	66.6	13%	0.128	35%	0.349	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-90.5	123.8	171.2	-51.2	173.9	0	0	0	108.9	M120 I178 W197 F208	M120-I195 HydrophobicContact CE-CD1 4.31Å; M120-I195 HydrophobicContact CE-CG1 3.78Å; I178-I195 HydrophobicContact CG1-CD1 4.25Å; I195-W197 HydrophobicContact CB-CZ2 4.17Å; I195-W197 HydrophobicContact CD1-CZ2 4.06Å; I195-W197 HydrophobicContact CG2-CD2 3.88Å; I195-W197 VanDerWaalsContact CG2-CE2 3.48Å; I195-W197 HydrophobicContact CG2-CE3 4.17Å; I195-W197 HydrophobicContact CG2-CH2 3.74Å; I195-W197 HydrophobicContact CG2-CZ2 3.44Å; I195-W197 VanDerWaalsContact CG2-CZ2 3.44Å; I195-W197 HydrophobicContact CG2-CZ3 4.11Å; I195-F208 HydrophobicContact CD1-CE1 4.46Å
196	V	87.3	Confident	83.3	Confident	63 Å²	63	66.7 Å²	66.7	38%	0.382	35%	0.352	S	S	.	.			trans	-101.4	93.2	-178.3	-171.8	0	0	0	0	108.9	Y181 I185 T194	Y181-V196 PolarHBondContact O-N 3.3Å; I185-V196 HydrophobicContact CG2-CG2 3.54Å; T194-V196 HydrophobicContact CG2-CG2 4.48Å
197	W	86.6	Confident	83.6	Confident	26 Å²	26	65.7 Å²	65.7	10%	0.098	35%	0.345	C	S	.	.	P	Polyproline II helix	trans	-71.7	144.3	-179.3	-62.2	112.5	0	0	0	112.2	Y181 I195 Q201 Y205 F208	Y181-W197 HydrophobicContact CD2-CE3 4.06Å; Y181-W197 AromaticContact CD2-CZ3 3.79Å; Y181-W197 HydrophobicContact CD2-CZ3 3.79Å; Y181-W197 HydrophobicContact CE2-CZ3 4.47Å; Y181-W197 HydrophobicContact CG-CE3 4.38Å; Y181-W197 HydrophobicContact CG-CZ3 4.42Å; I195-W197 HydrophobicContact CB-CZ2 4.17Å; I195-W197 HydrophobicContact CD1-CZ2 4.06Å; I195-W197 HydrophobicContact CG2-CD2 3.88Å; I195-W197 VanDerWaalsContact CG2-CE2 3.48Å; I195-W197 HydrophobicContact CG2-CE3 4.17Å; I195-W197 HydrophobicContact CG2-CH2 3.74Å; I195-W197 HydrophobicContact CG2-CZ2 3.44Å; I195-W197 VanDerWaalsContact CG2-CZ2 3.44Å; I195-W197 HydrophobicContact CG2-CZ3 4.11Å; W197-Q201 HydrophobicContact CB-CB 4.11Å; W197-Q201 HydrophobicContact CB-CG 4.26Å; W197-Q201 WeakPolarHBondContact O-CG 3.38Å; W197-Y205 AromaticContact NE1-CD2 3.62Å; W197-F208 HydrophobicContact CH2-CB 3.57Å; W197-F208 AromaticContact CH2-CD1 3.51Å; W197-F208 HydrophobicContact CH2-CD1 3.51Å; W197-F208 AromaticContact CH2-CD2 3.49Å; W197-F208 HydrophobicContact CH2-CD2 3.49Å; W197-F208 VanDerWaalsContact CH2-CD2 3.49Å; W197-F208 HydrophobicContact CH2-CE1 4.03Å; W197-F208 HydrophobicContact CH2-CE2 4.02Å; W197-F208 AromaticContact CH2-CG 3.21Å; W197-F208 HydrophobicContact CH2-CG 3.21Å; W197-F208 HydrophobicContact CH2-CZ 4.26Å; W197-F208 HydrophobicContact CZ2-CB 3.94Å; W197-F208 AromaticContact CZ2-CD1 3.43Å; W197-F208 HydrophobicContact CZ2-CD1 3.43Å; W197-F208 VanDerWaalsContact CZ2-CD1 3.43Å; W197-F208 HydrophobicContact CZ2-CD2 4.29Å; W197-F208 AromaticContact CZ2-CE1 3.96Å; W197-F208 HydrophobicContact CZ2-CE1 3.96Å; W197-F208 AromaticContact CZ2-CG 3.62Å; W197-F208 HydrophobicContact CZ2-CG 3.62Å; W197-F208 HydrophobicContact CZ3-CB 4.14Å; W197-F208 HydrophobicContact CZ3-CD2 4.29Å; W197-F208 HydrophobicContact CZ3-CG 4.15Å
198	P	89	Confident	84.1	Confident	36 Å²	36	63.7 Å²	63.7	23%	0.234	34%	0.337	C	S	.	.	P	Polyproline II helix	trans	-66.5	158.6	169.9	-17.9	31.2	0	0	0	112.4	Y181 P200 Q201 Y204	Y181-P198 HydrophobicContact CD1-CG 3.97Å; Y181-P198 HydrophobicContact CE1-CG 3.3Å; Y181-P198 HydrophobicContact CE2-CG 4.46Å; P198-P200 CarbonylContact O-C 3.49Å; P198-P200 VanDerWaalsContact O-C 3.26Å; P198-Q201 WeakPolarHBondContact O-CA 3.3Å; P198-Q201 PolarHBondContact O-N 3.43Å; P198-Q201 VanDerWaalsContact O-N 3.15Å; P198-Y204 HydrophobicContact CB-CD2 4.12Å; P198-Y204 HydrophobicContact CB-CE1 4.44Å; P198-Y204 HydrophobicContact CB-CE2 3.81Å; P198-Y204 HydrophobicContact CG-CD1 4.21Å; P198-Y204 HydrophobicContact CG-CD2 4.42Å; P198-Y204 HydrophobicContact CG-CE1 4.04Å; P198-Y204 HydrophobicContact CG-CE2 4.27Å; P198-Y204 HydrophobicContact CG-CG 4.4Å; P198-Y204 WeakPolarHBondContact O-CD2 3.46Å
199	E	85.6	Confident	84.7	Confident	170 Å²	170	55.4 Å²	55.4	79%	0.794	30%	0.299	S	S	*	.	S	Bend	trans	-72.3	136.8	169.4	-71.8	-178.3	-178.1	0	0	111.4
200	P	87.9	Confident	85.6	Confident	83 Å²	83	53.2 Å²	53.2	54%	0.539	28%	0.283	S	S	.	.	S	Bend	cis	-79.3	119.3	-4.8	30.1	-32.1	0	0	0	112.4	P198 E202 T203 Y204	P198-P200 CarbonylContact O-C 3.49Å; P198-P200 VanDerWaalsContact O-C 3.26Å; P200-E202 PolarHBondContact O-N 3.39Å; P200-T203 PolarHBondContact O-N 2.95Å; P200-T203 VanDerWaalsContact O-N 3.16Å; P200-Y204 WeakPolarHBondContact O-CD2 3.22Å; P200-Y204 PolarHBondContact O-N 2.99Å
201	Q	80.8	Confident	86.4	Confident	69 Å²	69	55.7 Å²	55.7	32%	0.322	29%	0.286	S	S	.	.	H	α-helix	trans	-62	-38.9	-167.8	-60.6	-170.8	20.5	0	0	113.3	H16 W197 P198 T203 Y204 Y205	H16-Q201 WeakPolarHBondContact CE1-CB 3.43Å; H16-Q201 VanDerWaalsContact CE1-CD 3.47Å; H16-Q201 PolarHBondContact CE1-OE1 3.48Å; W197-Q201 HydrophobicContact CB-CB 4.11Å; W197-Q201 HydrophobicContact CB-CG 4.26Å; W197-Q201 WeakPolarHBondContact O-CG 3.38Å; P198-Q201 WeakPolarHBondContact O-CA 3.3Å; P198-Q201 PolarHBondContact O-N 3.43Å; P198-Q201 VanDerWaalsContact O-N 3.15Å; Q201-T203 VanDerWaalsContact C-N 3.27Å; Q201-T203 PolarHBondContact O-N 3.3Å; Q201-Y204 PolarHBondContact O-N 3.22Å; Q201-Y205 WeakPolarHBondContact O-CB 3.1Å; Q201-Y205 PolarHBondContact O-N 2.98Å
202	E	80.9	Confident	86.6	Confident	59 Å²	59	54 Å²	54	28%	0.276	27%	0.274	S	S	.	.	H	α-helix	trans	-58.6	-37.7	179.1	-60.5	-60.1	164.7	0	0	112.8	H16 P200 T206	H16-E202 IonicContact CD2-OE1 3.13Å; H16-E202 PolarHBondContact CD2-OE1 3.03Å; H16-E202 IonicContact CE1-OE1 3.92Å; H16-E202 IonicContact CG-OE1 3.51Å; H16-E202 PolarHBondContact N-OE1 3.36Å; H16-E202 IonicContact NE2-OE1 3.48Å; H16-E202 PolarHBondContact NE2-OE1 2.6Å; P200-E202 PolarHBondContact O-N 3.39Å; E202-T206 VanDerWaalsContact O-CB 3.23Å; E202-T206 WeakPolarHBondContact O-CB 3.39Å; E202-T206 PolarHBondContact O-N 3.13Å; E202-T206 PolarHBondContact O-OG1 2.78Å
203	T	85.9	Confident	86.9	Confident	79 Å²	79	55.7 Å²	55.7	49%	0.485	28%	0.282	S	S	.	.	H	α-helix	trans	-69.7	-47.1	178.5	-59	0	0	0	0	110.7	P200 Q201 Y205 T206 V207	P200-T203 PolarHBondContact O-N 2.95Å; P200-T203 VanDerWaalsContact O-N 3.16Å; Q201-T203 VanDerWaalsContact C-N 3.27Å; Q201-T203 PolarHBondContact O-N 3.3Å; T203-Y205 PolarHBondContact O-N 3.04Å; T203-T206 PolarHBondContact O-N 3.47Å; T203-V207 HydrophobicContact CG2-CG2 4.36Å; T203-V207 WeakPolarHBondContact O-CB 3.28Å; T203-V207 VanDerWaalsContact O-CG2 3.22Å; T203-V207 WeakPolarHBondContact O-CG2 3.1Å; T203-V207 PolarHBondContact O-N 3.03Å
204	Y	87.3	Confident	87.1	Confident	96 Å²	96	59.3 Å²	59.3	38%	0.376	30%	0.299	S	S	.	.	H	α-helix	trans	-62.2	-44.4	178.6	-81.3	-88	0	0	0	111.9	P198 P200 Q201 F208	P198-Y204 HydrophobicContact CB-CD2 4.12Å; P198-Y204 HydrophobicContact CB-CE1 4.44Å; P198-Y204 HydrophobicContact CB-CE2 3.81Å; P198-Y204 HydrophobicContact CG-CD1 4.21Å; P198-Y204 HydrophobicContact CG-CD2 4.42Å; P198-Y204 HydrophobicContact CG-CE1 4.04Å; P198-Y204 HydrophobicContact CG-CE2 4.27Å; P198-Y204 HydrophobicContact CG-CG 4.4Å; P198-Y204 WeakPolarHBondContact O-CD2 3.46Å; P200-Y204 WeakPolarHBondContact O-CD2 3.22Å; P200-Y204 PolarHBondContact O-N 2.99Å; Q201-Y204 PolarHBondContact O-N 3.22Å; Y204-F208 WeakPolarHBondContact O-CB 3.3Å; Y204-F208 PolarHBondContact O-N 2.84Å
205	Y	83.4	Confident	87.5	Confident	34 Å²	34	60.8 Å²	60.8	13%	0.133	31%	0.307	C	S	.	.	H	α-helix	trans	-60.8	-49.6	176.4	177.9	-102	0	0	0	111.8	W197 Q201 T203 V207 F208 M209 V280	W197-Y205 AromaticContact NE1-CD2 3.62Å; Q201-Y205 WeakPolarHBondContact O-CB 3.1Å; Q201-Y205 PolarHBondContact O-N 2.98Å; T203-Y205 PolarHBondContact O-N 3.04Å; Y205-V207 PolarHBondContact O-N 3.01Å; Y205-F208 PolarHBondContact O-N 3.24Å; Y205-M209 HydrophobicContact CD1-CG 4.45Å; Y205-M209 HydrophobicContact CD2-CE 4.37Å; Y205-M209 HydrophobicContact CE1-CE 4.33Å; Y205-M209 HydrophobicContact CE1-CG 4.14Å; Y205-M209 HydrophobicContact CE2-CE 3.41Å; Y205-M209 VanDerWaalsContact CE2-CE 3.41Å; Y205-M209 HydrophobicContact CE2-CG 4.28Å; Y205-M209 WeakPolarHBondContact O-CG 3.45Å; Y205-M209 PolarHBondContact O-N 3.29Å; Y205-M209 WeakPolarHBondContact OH-CE 3.44Å; Y205-V280 HydrophobicContact CD1-CG2 4.1Å; Y205-V280 HydrophobicContact CE1-CG2 3.59Å
206	T	85.3	Confident	87.7	Confident	41 Å²	41	59.6 Å²	59.6	25%	0.252	30%	0.301	S	S	.	.	H	α-helix	trans	-60.1	-48.3	178.9	-64	0	0	0	0	111.6	E202 T203 F208 M209 F210 V280	E202-T206 VanDerWaalsContact O-CB 3.23Å; E202-T206 WeakPolarHBondContact O-CB 3.39Å; E202-T206 PolarHBondContact O-N 3.13Å; E202-T206 PolarHBondContact O-OG1 2.78Å; T203-T206 PolarHBondContact O-N 3.47Å; T206-F208 VanDerWaalsContact C-N 3.33Å; T206-F208 PolarHBondContact O-N 3.13Å; T206-M209 PolarHBondContact O-N 2.94Å; T206-F210 HydrophobicContact CG2-CD2 3.84Å; T206-F210 HydrophobicContact CG2-CE2 3.78Å; T206-F210 VanDerWaalsContact O-CD2 3.3Å; T206-F210 WeakPolarHBondContact O-CD2 3.45Å; T206-F210 PolarHBondContact O-N 3.48Å; T206-F210 VanDerWaalsContact O-N 3.08Å; T206-V280 HydrophobicContact CG2-CG1 3.93Å
207	V	89.9	Confident	87.8	Confident	94 Å²	94	57.3 Å²	57.3	57%	0.57	29%	0.286	S	S	*	.	H	α-helix	trans	-60.4	-45.6	177.7	169.7	0	0	0	0	110.4	T203 Y205 M209 F210 Y211	T203-V207 HydrophobicContact CG2-CG2 4.36Å; T203-V207 WeakPolarHBondContact O-CB 3.28Å; T203-V207 VanDerWaalsContact O-CG2 3.22Å; T203-V207 WeakPolarHBondContact O-CG2 3.1Å; T203-V207 PolarHBondContact O-N 3.03Å; Y205-V207 PolarHBondContact O-N 3.01Å; V207-M209 PolarHBondContact O-N 3.19Å; V207-F210 PolarHBondContact O-N 2.91Å; V207-Y211 WeakPolarHBondContact O-CB 3.22Å; V207-Y211 PolarHBondContact O-N 2.78Å
208	F	88.2	Confident	88.1	Confident	24 Å²	24	61.4 Å²	61.4	11%	0.105	30%	0.304	C	S	.	.	H	α-helix	trans	-62	-41.1	178.4	177.3	-102.1	0	0	0	112.3	P177 I178 I195 W197 Y204 Y205 T206 Y211 T212	P177-F208 HydrophobicContact CB-CD2 4.16Å; P177-F208 HydrophobicContact CB-CE2 4.19Å; I178-F208 HydrophobicContact CD1-CE2 4.01Å; I178-F208 HydrophobicContact CD1-CZ 3.46Å; I178-F208 VanDerWaalsContact CD1-CZ 3.46Å; I178-F208 HydrophobicContact CG1-CE2 3.81Å; I178-F208 HydrophobicContact CG1-CZ 3.55Å; I195-F208 HydrophobicContact CD1-CE1 4.46Å; W197-F208 HydrophobicContact CH2-CB 3.57Å; W197-F208 AromaticContact CH2-CD1 3.51Å; W197-F208 HydrophobicContact CH2-CD1 3.51Å; W197-F208 AromaticContact CH2-CD2 3.49Å; W197-F208 HydrophobicContact CH2-CD2 3.49Å; W197-F208 VanDerWaalsContact CH2-CD2 3.49Å; W197-F208 HydrophobicContact CH2-CE1 4.03Å; W197-F208 HydrophobicContact CH2-CE2 4.02Å; W197-F208 AromaticContact CH2-CG 3.21Å; W197-F208 HydrophobicContact CH2-CG 3.21Å; W197-F208 HydrophobicContact CH2-CZ 4.26Å; W197-F208 HydrophobicContact CZ2-CB 3.94Å; W197-F208 AromaticContact CZ2-CD1 3.43Å; W197-F208 HydrophobicContact CZ2-CD1 3.43Å; W197-F208 VanDerWaalsContact CZ2-CD1 3.43Å; W197-F208 HydrophobicContact CZ2-CD2 4.29Å; W197-F208 AromaticContact CZ2-CE1 3.96Å; W197-F208 HydrophobicContact CZ2-CE1 3.96Å; W197-F208 AromaticContact CZ2-CG 3.62Å; W197-F208 HydrophobicContact CZ2-CG 3.62Å; W197-F208 HydrophobicContact CZ3-CB 4.14Å; W197-F208 HydrophobicContact CZ3-CD2 4.29Å; W197-F208 HydrophobicContact CZ3-CG 4.15Å; Y204-F208 WeakPolarHBondContact O-CB 3.3Å; Y204-F208 PolarHBondContact O-N 2.84Å; Y205-F208 PolarHBondContact O-N 3.24Å; T206-F208 VanDerWaalsContact C-N 3.33Å; T206-F208 PolarHBondContact O-N 3.13Å; F208-Y211 HydrophobicContact CD2-CD1 4.29Å; F208-Y211 WeakPolarHBondContact O-CB 3.5Å; F208-Y211 PolarHBondContact O-N 3.38Å; F208-T212 HydrophobicContact CD1-CG2 4.26Å; F208-T212 HydrophobicContact CD2-CG2 3.97Å; F208-T212 HydrophobicContact CE1-CG2 3.83Å; F208-T212 HydrophobicContact CE2-CG2 3.5Å; F208-T212 VanDerWaalsContact CE2-CG2 3.5Å; F208-T212 HydrophobicContact CG-CG2 4.33Å; F208-T212 HydrophobicContact CZ-CG2 3.4Å; F208-T212 VanDerWaalsContact CZ-CG2 3.4Å; F208-T212 WeakPolarHBondContact O-CB 3.38Å; F208-T212 VanDerWaalsContact O-CG2 3.3Å; F208-T212 WeakPolarHBondContact O-CG2 3.45Å; F208-T212 PolarHBondContact O-N 3.45Å; F208-T212 PolarHBondContact O-OG1 3.4Å
209	M	85.4	Confident	88.3	Confident	21 Å²	21	63.4 Å²	63.4	10%	0.103	31%	0.312	C	S	.	.	H	α-helix	trans	-63.2	-49.4	177.1	-76.6	-59.3	-169.8	0	0	112.6	Y205 T206 V207 Y211 T212 F213 N276	Y205-M209 HydrophobicContact CD1-CG 4.45Å; Y205-M209 HydrophobicContact CD2-CE 4.37Å; Y205-M209 HydrophobicContact CE1-CE 4.33Å; Y205-M209 HydrophobicContact CE1-CG 4.14Å; Y205-M209 HydrophobicContact CE2-CE 3.41Å; Y205-M209 VanDerWaalsContact CE2-CE 3.41Å; Y205-M209 HydrophobicContact CE2-CG 4.28Å; Y205-M209 WeakPolarHBondContact O-CG 3.45Å; Y205-M209 PolarHBondContact O-N 3.29Å; Y205-M209 WeakPolarHBondContact OH-CE 3.44Å; T206-M209 PolarHBondContact O-N 2.94Å; V207-M209 PolarHBondContact O-N 3.19Å; M209-Y211 VanDerWaalsContact C-N 3.33Å; M209-Y211 PolarHBondContact O-N 3.17Å; M209-T212 PolarHBondContact O-N 3.33Å; M209-T212 PolarHBondContact O-OG1 3.16Å; M209-T212 VanDerWaalsContact O-OG1 3.05Å; M209-F213 VanDerWaalsContact O-CB 3.29Å; M209-F213 WeakPolarHBondContact O-CB 3.2Å; M209-F213 PolarHBondContact O-N 2.89Å; M209-N276 HydrophobicContact CE-CB 4Å; M209-N276 WeakPolarHBondContact CE-OD1 3.41Å; M209-N276 HydrophobicContact SD-CB 3.81Å
210	F	89.5	Confident	88.7	Confident	94 Å²	94	55.3 Å²	55.3	41%	0.412	28%	0.275	S	S	.	.	H	α-helix	trans	-64.6	-40.1	176.6	-78.8	-69.2	0	0	0	112.1	T206 V207 F213 I214	T206-F210 HydrophobicContact CG2-CD2 3.84Å; T206-F210 HydrophobicContact CG2-CE2 3.78Å; T206-F210 VanDerWaalsContact O-CD2 3.3Å; T206-F210 WeakPolarHBondContact O-CD2 3.45Å; T206-F210 PolarHBondContact O-N 3.48Å; T206-F210 VanDerWaalsContact O-N 3.08Å; V207-F210 PolarHBondContact O-N 2.91Å; F210-F213 PolarHBondContact O-N 3.17Å; F210-I214 WeakPolarHBondContact O-CB 3.47Å; F210-I214 WeakPolarHBondContact O-CD1 3.43Å; F210-I214 WeakPolarHBondContact O-CG1 3.13Å; F210-I214 PolarHBondContact O-N 3.06Å
211	Y	91.7	Very high	88.9	Confident	74 Å²	74	52.3 Å²	52.3	29%	0.29	25%	0.254	S	S	.	.	H	α-helix	trans	-56.8	-52	175	166	-98.3	0	0	0	112	V174 V207 F208 M209 I214 L215	V174-Y211 WeakPolarHBondContact CA-OH 3.41Å; V174-Y211 HydrophobicContact CG1-CE1 3.99Å; V174-Y211 WeakPolarHBondContact CG1-OH 3.31Å; V174-Y211 PolarHBondContact O-OH 2.68Å; V174-Y211 VanDerWaalsContact O-OH 3.07Å; V207-Y211 WeakPolarHBondContact O-CB 3.22Å; V207-Y211 PolarHBondContact O-N 2.78Å; F208-Y211 HydrophobicContact CD2-CD1 4.29Å; F208-Y211 WeakPolarHBondContact O-CB 3.5Å; F208-Y211 PolarHBondContact O-N 3.38Å; M209-Y211 VanDerWaalsContact C-N 3.33Å; M209-Y211 PolarHBondContact O-N 3.17Å; Y211-I214 PolarHBondContact O-N 3.36Å; Y211-L215 HydrophobicContact CD2-CD1 3.76Å; Y211-L215 HydrophobicContact CD2-CG 4.45Å; Y211-L215 HydrophobicContact CE1-CD1 4.31Å; Y211-L215 HydrophobicContact CE2-CD1 3.19Å; Y211-L215 HydrophobicContact CE2-CG 4.3Å; Y211-L215 WeakPolarHBondContact O-CB 3.24Å; Y211-L215 PolarHBondContact O-N 3.26Å
212	T	89.6	Confident	89.5	Confident	8 Å²	8	52.7 Å²	52.7	5%	0.049	26%	0.258	C	S	.	.	H	α-helix	trans	-69.6	-34.8	-179.9	55.6	0	0	0	0	112.2	F128 F208 M209 G216	F128-T212 HydrophobicContact CZ-CG2 3.86Å; F208-T212 HydrophobicContact CD1-CG2 4.26Å; F208-T212 HydrophobicContact CD2-CG2 3.97Å; F208-T212 HydrophobicContact CE1-CG2 3.83Å; F208-T212 HydrophobicContact CE2-CG2 3.5Å; F208-T212 VanDerWaalsContact CE2-CG2 3.5Å; F208-T212 HydrophobicContact CG-CG2 4.33Å; F208-T212 HydrophobicContact CZ-CG2 3.4Å; F208-T212 VanDerWaalsContact CZ-CG2 3.4Å; F208-T212 WeakPolarHBondContact O-CB 3.38Å; F208-T212 VanDerWaalsContact O-CG2 3.3Å; F208-T212 WeakPolarHBondContact O-CG2 3.45Å; F208-T212 PolarHBondContact O-N 3.45Å; F208-T212 PolarHBondContact O-OG1 3.4Å; M209-T212 PolarHBondContact O-N 3.33Å; M209-T212 PolarHBondContact O-OG1 3.16Å; M209-T212 VanDerWaalsContact O-OG1 3.05Å; T212-G216 WeakPolarHBondContact O-CA 3.27Å; T212-G216 PolarHBondContact O-N 3.08Å
213	F	90.6	Very high	90.2	Very high	54 Å²	54	51.8 Å²	51.8	24%	0.237	26%	0.256	C	S	.	.	H	α-helix	trans	-61	-47.7	171.4	173.5	-108.7	0	0	0	112.2	M209 F210 F217 F218 Y273	M209-F213 VanDerWaalsContact O-CB 3.29Å; M209-F213 WeakPolarHBondContact O-CB 3.2Å; M209-F213 PolarHBondContact O-N 2.89Å; F210-F213 PolarHBondContact O-N 3.17Å; F213-F217 HydrophobicContact CD2-CB 4.29Å; F213-F217 HydrophobicContact CD2-CD1 4.24Å; F213-F217 AromaticContact CE2-CD1 3.69Å; F213-F217 HydrophobicContact CE2-CD1 3.69Å; F213-F217 HydrophobicContact CE2-CE1 4.36Å; F213-F217 HydrophobicContact CE2-CG 4.46Å; F213-F217 HydrophobicContact CZ-CD1 4.43Å; F213-F217 WeakPolarHBondContact O-CA 3.31Å; F213-F217 VanDerWaalsContact O-CB 3.28Å; F213-F217 WeakPolarHBondContact O-CB 3.49Å; F213-F217 PolarHBondContact O-N 3.1Å; F213-F217 VanDerWaalsContact O-N 3.09Å; F213-F218 HydrophobicContact CE1-CB 4.27Å; F213-F218 HydrophobicContact CZ-CB 4.45Å; F213-F218 PolarHBondContact O-N 2.91Å; F213-Y273 HydrophobicContact CB-CD1 3.99Å; F213-Y273 HydrophobicContact CB-CE1 4.27Å; F213-Y273 AromaticContact CD2-CD1 3.75Å; F213-Y273 HydrophobicContact CD2-CD1 3.75Å; F213-Y273 HydrophobicContact CD2-CE1 4.48Å; F213-Y273 AromaticContact CD2-CG 3.76Å; F213-Y273 HydrophobicContact CD2-CG 3.76Å; F213-Y273 HydrophobicContact CE2-CG 4.44Å; F213-Y273 HydrophobicContact CG-CD1 4.39Å
214	I	93.1	Very high	90.4	Very high	82 Å²	82	48.1 Å²	48.1	42%	0.421	23%	0.234	S	C	.	.	I	π-helix	trans	-65.8	-49.9	-178.1	-69	166.3	0	0	0	110.4	F210 Y211 F218 L219	F210-I214 WeakPolarHBondContact O-CB 3.47Å; F210-I214 WeakPolarHBondContact O-CD1 3.43Å; F210-I214 WeakPolarHBondContact O-CG1 3.13Å; F210-I214 PolarHBondContact O-N 3.06Å; Y211-I214 PolarHBondContact O-N 3.36Å; I214-F218 PolarHBondContact O-N 3.04Å; I214-L219 VanDerWaalsContact O-CB 3.28Å; I214-L219 WeakPolarHBondContact O-CB 3.36Å; I214-L219 PolarHBondContact O-N 3.2Å
215	L	93.2	Very high	90.5	Very high	45 Å²	45	47 Å²	47	24%	0.236	24%	0.239	C	C	.	.	I	π-helix	trans	-82.3	-34	-173.8	-63.6	-174.7	0	0	0	113.8	F132 V174 Y211 L219 P220	F132-L215 WeakPolarHBondContact CE1-O 3.02Å; V174-L215 HydrophobicContact CG1-CB 4.48Å; V174-L215 HydrophobicContact CG1-CD1 4.13Å; V174-L215 HydrophobicContact CG2-CD1 4.13Å; Y211-L215 HydrophobicContact CD2-CD1 3.76Å; Y211-L215 HydrophobicContact CD2-CG 4.45Å; Y211-L215 HydrophobicContact CE1-CD1 4.31Å; Y211-L215 HydrophobicContact CE2-CD1 3.19Å; Y211-L215 HydrophobicContact CE2-CG 4.3Å; Y211-L215 WeakPolarHBondContact O-CB 3.24Å; Y211-L215 PolarHBondContact O-N 3.26Å; L215-L219 HydrophobicContact CD2-CD2 4.24Å; L215-P220 VanDerWaalsContact O-CD 3.25Å; L215-P220 WeakPolarHBondContact O-CD 3.34Å; L215-P220 WeakPolarHBondContact O-CG 3.45Å
216	G	90.1	Very high	90.9	Very high	0 Å²	0	49.5 Å²	49.5	0%	0	25%	0.254	C	S	.	.	I	π-helix	trans	-91.5	-9.3	-177.3	0	0	0	0	0	114.4	T212 Y273	T212-G216 WeakPolarHBondContact O-CA 3.27Å; T212-G216 PolarHBondContact O-N 3.08Å; G216-Y273 WeakPolarHBondContact CA-OH 3.37Å; G216-Y273 PolarHBondContact O-OH 3.12Å
217	F	90.2	Very high	91.2	Very high	15 Å²	15	48.1 Å²	48.1	7%	0.066	25%	0.246	C	C	.	.	I	π-helix	trans	-140.2	-66.3	-178.3	-167.2	-102	0	0	0	113.3	F213 P220 L221 F265 V266 W269 L270 Y273	F213-F217 HydrophobicContact CD2-CB 4.29Å; F213-F217 HydrophobicContact CD2-CD1 4.24Å; F213-F217 AromaticContact CE2-CD1 3.69Å; F213-F217 HydrophobicContact CE2-CD1 3.69Å; F213-F217 HydrophobicContact CE2-CE1 4.36Å; F213-F217 HydrophobicContact CE2-CG 4.46Å; F213-F217 HydrophobicContact CZ-CD1 4.43Å; F213-F217 WeakPolarHBondContact O-CA 3.31Å; F213-F217 VanDerWaalsContact O-CB 3.28Å; F213-F217 WeakPolarHBondContact O-CB 3.49Å; F213-F217 PolarHBondContact O-N 3.1Å; F213-F217 VanDerWaalsContact O-N 3.09Å; F217-P220 WeakPolarHBondContact O-CD 3.03Å; F217-L221 HydrophobicContact CD1-CD1 3.65Å; F217-L221 HydrophobicContact CD2-CD1 3.62Å; F217-L221 HydrophobicContact CE1-CD1 3.4Å; F217-L221 VanDerWaalsContact CE1-CD1 3.4Å; F217-L221 HydrophobicContact CE2-CD1 3.4Å; F217-L221 HydrophobicContact CG-CD1 3.73Å; F217-L221 HydrophobicContact CZ-CD1 3.26Å; F217-L221 VanDerWaalsContact O-CB 3.24Å; F217-L221 WeakPolarHBondContact O-CB 3.27Å; F217-L221 WeakPolarHBondContact O-CD1 3.33Å; F217-L221 VanDerWaalsContact O-CG 3.31Å; F217-L221 WeakPolarHBondContact O-CG 3.4Å; F217-L221 PolarHBondContact O-N 2.96Å; F217-F265 AromaticContact CD2-CE1 3.91Å; F217-F265 HydrophobicContact CD2-CE1 3.91Å; F217-F265 HydrophobicContact CE2-CE1 4.28Å; F217-V266 HydrophobicContact CZ-CG1 4.41Å; F217-W269 HydrophobicContact CD2-CB 4.22Å; F217-W269 HydrophobicContact CE2-CB 4.18Å; F217-L270 HydrophobicContact CE1-CD1 3.78Å; F217-L270 HydrophobicContact CE2-CB 4.19Å; F217-L270 HydrophobicContact CZ-CB 3.77Å; F217-L270 HydrophobicContact CZ-CD1 3.63Å; F217-L270 HydrophobicContact CZ-CG 4.27Å; F217-Y273 HydrophobicContact CB-CD2 3.76Å; F217-Y273 HydrophobicContact CB-CE1 4.4Å; F217-Y273 HydrophobicContact CB-CE2 3.42Å; F217-Y273 VanDerWaalsContact CB-CE2 3.42Å; F217-Y273 HydrophobicContact CB-CG 4.38Å; F217-Y273 HydrophobicContact CD1-CD2 4.37Å; F217-Y273 AromaticContact CD2-CD2 3.55Å; F217-Y273 HydrophobicContact CD2-CD2 3.55Å; F217-Y273 AromaticContact CD2-CE2 3.51Å; F217-Y273 HydrophobicContact CD2-CE2 3.51Å; F217-Y273 HydrophobicContact CE2-CD2 4.2Å; F217-Y273 HydrophobicContact CE2-CE2 4.48Å; F217-Y273 AromaticContact CG-CD2 3.64Å; F217-Y273 HydrophobicContact CG-CD2 3.64Å; F217-Y273 AromaticContact CG-CE2 3.69Å; F217-Y273 HydrophobicContact CG-CE2 3.69Å; F217-Y273 HydrophobicContact CG-CG 4.43Å
218	F	92.2	Very high	91.1	Very high	112 Å²	112	44.6 Å²	44.6	49%	0.491	22%	0.223	S	C	.	.	I	π-helix	trans	-64.4	-54.5	-167.8	179.5	-99.1	0	0	0	113.2	F213 I214 L221 L222	F213-F218 HydrophobicContact CE1-CB 4.27Å; F213-F218 HydrophobicContact CZ-CB 4.45Å; F213-F218 PolarHBondContact O-N 2.91Å; I214-F218 PolarHBondContact O-N 3.04Å; F218-L221 PolarHBondContact O-N 2.87Å; F218-L222 HydrophobicContact CE1-CD2 4.49Å; F218-L222 WeakPolarHBondContact O-CB 3.48Å; F218-L222 PolarHBondContact O-N 3.47Å
219	L	94.3	Very high	91	Very high	77 Å²	77	47.9 Å²	47.9	40%	0.403	24%	0.241	S	C	.	.	H	α-helix	trans	-63.5	-46.3	-178	177.7	71.1	0	0	0	111.7	I214 L215 L221 L222 V223	I214-L219 VanDerWaalsContact O-CB 3.28Å; I214-L219 WeakPolarHBondContact O-CB 3.36Å; I214-L219 PolarHBondContact O-N 3.2Å; L215-L219 HydrophobicContact CD2-CD2 4.24Å; L219-L221 PolarHBondContact O-N 3.09Å; L219-L222 PolarHBondContact O-N 3.4Å; L219-V223 WeakPolarHBondContact O-CG2 3.22Å; L219-V223 PolarHBondContact O-N 3.29Å; L219-V223 VanDerWaalsContact O-N 3.1Å
220	P	93.4	Very high	91.1	Very high	0 Å²	0	50.6 Å²	50.6	0%	0	26%	0.256	C	S	.	.	H	α-helix	trans	-59.4	-44.4	173.1	-25	34	0	0	0	114.7	I131 F132 M135 L215 F217 L222 V223 I224	I131-P220 HydrophobicContact CD1-CB 3.95Å; I131-P220 HydrophobicContact CG1-CB 3.35Å; I131-P220 HydrophobicContact CG1-CG 3.82Å; I131-P220 HydrophobicContact CG2-CG 4.24Å; F132-P220 HydrophobicContact CD1-CG 4.27Å; F132-P220 HydrophobicContact CE1-CG 4.04Å; M135-P220 VanDerWaalsContact CE-CA 3.41Å; M135-P220 HydrophobicContact CE-CB 3.69Å; M135-P220 HydrophobicContact CE-CG 3.87Å; L215-P220 VanDerWaalsContact O-CD 3.25Å; L215-P220 WeakPolarHBondContact O-CD 3.34Å; L215-P220 WeakPolarHBondContact O-CG 3.45Å; F217-P220 WeakPolarHBondContact O-CD 3.03Å; P220-L222 VanDerWaalsContact C-N 3.33Å; P220-L222 PolarHBondContact O-N 2.94Å; P220-V223 PolarHBondContact O-N 2.8Å; P220-I224 WeakPolarHBondContact O-CB 3.2Å; P220-I224 WeakPolarHBondContact O-CD1 3.38Å; P220-I224 WeakPolarHBondContact O-CG1 3.2Å; P220-I224 PolarHBondContact O-N 2.67Å
221	L	91.8	Very high	91	Very high	20 Å²	20	46.3 Å²	46.3	11%	0.105	24%	0.237	C	C	.	.	H	α-helix	trans	-63.7	-40.3	178.1	-80.5	166.2	0	0	0	112	F217 F218 L219 V223 I224 C225 V262 V266	F217-L221 HydrophobicContact CD1-CD1 3.65Å; F217-L221 HydrophobicContact CD2-CD1 3.62Å; F217-L221 HydrophobicContact CE1-CD1 3.4Å; F217-L221 VanDerWaalsContact CE1-CD1 3.4Å; F217-L221 HydrophobicContact CE2-CD1 3.4Å; F217-L221 HydrophobicContact CG-CD1 3.73Å; F217-L221 HydrophobicContact CZ-CD1 3.26Å; F217-L221 VanDerWaalsContact O-CB 3.24Å; F217-L221 WeakPolarHBondContact O-CB 3.27Å; F217-L221 WeakPolarHBondContact O-CD1 3.33Å; F217-L221 VanDerWaalsContact O-CG 3.31Å; F217-L221 WeakPolarHBondContact O-CG 3.4Å; F217-L221 PolarHBondContact O-N 2.96Å; F218-L221 PolarHBondContact O-N 2.87Å; L219-L221 PolarHBondContact O-N 3.09Å; L221-V223 PolarHBondContact O-N 2.94Å; L221-I224 PolarHBondContact O-N 2.89Å; L221-C225 VanDerWaalsContact O-CB 3.25Å; L221-C225 WeakPolarHBondContact O-CB 3.38Å; L221-C225 PolarHBondContact O-N 3.4Å; L221-C225 PolarHBondContact O-SG 3.38Å; L221-V262 HydrophobicContact CD2-CG1 4.09Å; L221-V266 HydrophobicContact CD1-CG2 3.95Å; L221-V266 HydrophobicContact CD2-CG2 3.34Å; L221-V266 HydrophobicContact CG-CG2 4.31Å
222	L	93.4	Very high	90.6	Very high	78 Å²	78	46.9 Å²	46.9	41%	0.408	24%	0.244	S	C	.	.	H	α-helix	trans	-57.3	-50.9	175.2	179.2	63.1	0	0	0	111	F218 L219 P220 I224 C225 L226	F218-L222 HydrophobicContact CE1-CD2 4.49Å; F218-L222 WeakPolarHBondContact O-CB 3.48Å; F218-L222 PolarHBondContact O-N 3.47Å; L219-L222 PolarHBondContact O-N 3.4Å; P220-L222 VanDerWaalsContact C-N 3.33Å; P220-L222 PolarHBondContact O-N 2.94Å; L222-I224 VanDerWaalsContact C-N 3.34Å; L222-I224 PolarHBondContact O-N 3.29Å; L222-C225 PolarHBondContact O-N 2.93Å; L222-L226 HydrophobicContact CD1-CD1 4.11Å; L222-L226 HydrophobicContact CD1-CG 4.27Å; L222-L226 HydrophobicContact CG-CD1 4.06Å; L222-L226 WeakPolarHBondContact O-CB 3.34Å; L222-L226 VanDerWaalsContact O-CG 3.23Å; L222-L226 WeakPolarHBondContact O-CG 3.29Å; L222-L226 PolarHBondContact O-N 2.88Å
223	V	95	Very high	90.3	Very high	40 Å²	40	50.9 Å²	50.9	24%	0.242	26%	0.264	C	S	.	.	H	α-helix	trans	-60.6	-44.6	178.7	173.9	0	0	0	0	111.3	M135 I139 L219 P220 L221 L226 C227	M135-V223 HydrophobicContact CE-CB 4.38Å; M135-V223 HydrophobicContact CE-CG2 4.38Å; M135-V223 HydrophobicContact CG-CB 3.98Å; M135-V223 HydrophobicContact CG-CG1 3.59Å; M135-V223 HydrophobicContact SD-CB 4.24Å; M135-V223 HydrophobicContact SD-CG1 3.96Å; M135-V223 HydrophobicContact SD-CG2 4.44Å; I139-V223 HydrophobicContact CD1-CG1 4.05Å; I139-V223 HydrophobicContact CG1-CG1 4.2Å; L219-V223 WeakPolarHBondContact O-CG2 3.22Å; L219-V223 PolarHBondContact O-N 3.29Å; L219-V223 VanDerWaalsContact O-N 3.1Å; P220-V223 PolarHBondContact O-N 2.8Å; L221-V223 PolarHBondContact O-N 2.94Å; V223-L226 PolarHBondContact O-N 3.29Å; V223-C227 WeakPolarHBondContact O-CB 3.42Å; V223-C227 PolarHBondContact O-N 3.42Å; V223-C227 PolarHBondContact O-SG 3.06Å
224	I	91.6	Very high	90	Very high	1 Å²	1	52.5 Å²	52.5	1%	0.005	27%	0.271	C	S	.	.	H	α-helix	trans	-60.4	-51.9	178	-72.5	168.2	0	0	0	110.5	I131 L134 M135 P220 L221 L222 L226 C227 Y228 V262	I131-I224 HydrophobicContact CD1-CD1 3.89Å; L134-I224 HydrophobicContact CB-CD1 4.36Å; M135-I224 HydrophobicContact CB-CD1 4.32Å; M135-I224 HydrophobicContact CB-CG1 4.19Å; M135-I224 HydrophobicContact CG-CG1 4.36Å; P220-I224 WeakPolarHBondContact O-CB 3.2Å; P220-I224 WeakPolarHBondContact O-CD1 3.38Å; P220-I224 WeakPolarHBondContact O-CG1 3.2Å; P220-I224 PolarHBondContact O-N 2.67Å; L221-I224 PolarHBondContact O-N 2.89Å; L222-I224 VanDerWaalsContact C-N 3.34Å; L222-I224 PolarHBondContact O-N 3.29Å; I224-L226 PolarHBondContact O-N 3.05Å; I224-C227 WeakPolarHBondContact O-CB 3.29Å; I224-C227 PolarHBondContact O-N 3.39Å; I224-Y228 HydrophobicContact CG2-CD2 3.81Å; I224-Y228 HydrophobicContact CG2-CE2 3.7Å; I224-Y228 WeakPolarHBondContact O-CD2 3.3Å; I224-Y228 PolarHBondContact O-N 3.49Å; I224-V262 HydrophobicContact CD1-CG2 4.37Å; I224-V262 HydrophobicContact CG2-CB 4.19Å; I224-V262 HydrophobicContact CG2-CG1 3.65Å; I224-V262 HydrophobicContact CG2-CG2 3.48Å; I224-V262 VanDerWaalsContact CG2-CG2 3.48Å
225	C	89.3	Confident	89.2	Confident	73 Å²	73	51 Å²	51	49%	0.493	27%	0.266	S	S	.	.	H	α-helix	trans	-58.9	-44.7	179.2	-74.4	0	0	0	0	111.8	L221 L222 C227 Y228 L229	L221-C225 VanDerWaalsContact O-CB 3.25Å; L221-C225 WeakPolarHBondContact O-CB 3.38Å; L221-C225 PolarHBondContact O-N 3.4Å; L221-C225 PolarHBondContact O-SG 3.38Å; L222-C225 PolarHBondContact O-N 2.93Å; C225-C227 PolarHBondContact O-N 3.29Å; C225-Y228 PolarHBondContact O-N 3.4Å; C225-L229 WeakPolarHBondContact O-CB 3.46Å; C225-L229 PolarHBondContact O-N 3.46Å
226	L	92.1	Very high	88.5	Confident	86 Å²	86	56.8 Å²	56.8	45%	0.45	29%	0.289	S	S	.	.	H	α-helix	trans	-61.3	-43.9	175.4	-70.7	173.2	0	0	0	111.6	L222 V223 I224 Y228 L229 L230	L222-L226 HydrophobicContact CD1-CD1 4.11Å; L222-L226 HydrophobicContact CD1-CG 4.27Å; L222-L226 HydrophobicContact CG-CD1 4.06Å; L222-L226 WeakPolarHBondContact O-CB 3.34Å; L222-L226 VanDerWaalsContact O-CG 3.23Å; L222-L226 WeakPolarHBondContact O-CG 3.29Å; L222-L226 PolarHBondContact O-N 2.88Å; V223-L226 PolarHBondContact O-N 3.29Å; I224-L226 PolarHBondContact O-N 3.05Å; L226-Y228 VanDerWaalsContact C-N 3.35Å; L226-Y228 PolarHBondContact O-N 3.38Å; L226-L229 PolarHBondContact O-N 3.37Å; L226-L230 WeakPolarHBondContact O-CB 3.47Å; L226-L230 VanDerWaalsContact O-CG 3.25Å; L226-L230 WeakPolarHBondContact O-CG 3.35Å; L226-L230 PolarHBondContact O-N 3.01Å
227	C	91.4	Very high	87.8	Confident	12 Å²	12	61.4 Å²	61.4	8%	0.081	32%	0.321	C	S	.	.	H	α-helix	trans	-57.5	-47	175.5	-71.6	0	0	0	0	111.5	V223 I224 C225 L230 I231	V223-C227 WeakPolarHBondContact O-CB 3.42Å; V223-C227 PolarHBondContact O-N 3.42Å; V223-C227 PolarHBondContact O-SG 3.06Å; I224-C227 WeakPolarHBondContact O-CB 3.29Å; I224-C227 PolarHBondContact O-N 3.39Å; C225-C227 PolarHBondContact O-N 3.29Å; C227-L230 PolarHBondContact O-N 2.92Å; C227-I231 WeakPolarHBondContact O-CD1 3.43Å; C227-I231 WeakPolarHBondContact O-CG1 3.34Å; C227-I231 PolarHBondContact O-N 3.19Å
228	Y	86.4	Confident	86.9	Confident	21 Å²	21	62.7 Å²	62.7	8%	0.082	33%	0.332	C	S	.	.	H	α-helix	trans	-68.3	-39.9	178.8	-78.2	-70.3	0	0	0	113.3	S138 I224 C225 L226 L230 I231 I232 T255 V258 S259 V262	S138-Y228 WeakPolarHBondContact OG-CE2 3.29Å; S138-Y228 PolarHBondContact OG-OH 3.25Å; I224-Y228 HydrophobicContact CG2-CD2 3.81Å; I224-Y228 HydrophobicContact CG2-CE2 3.7Å; I224-Y228 WeakPolarHBondContact O-CD2 3.3Å; I224-Y228 PolarHBondContact O-N 3.49Å; C225-Y228 PolarHBondContact O-N 3.4Å; L226-Y228 VanDerWaalsContact C-N 3.35Å; L226-Y228 PolarHBondContact O-N 3.38Å; Y228-L230 VanDerWaalsContact C-N 3.33Å; Y228-L230 PolarHBondContact O-N 2.87Å; Y228-I231 HydrophobicContact CD1-CD1 4.24Å; Y228-I231 HydrophobicContact CE1-CD1 4.39Å; Y228-I231 WeakPolarHBondContact O-CB 3.13Å; Y228-I231 PolarHBondContact O-N 3.39Å; Y228-I232 VanDerWaalsContact O-CG1 3.28Å; Y228-I232 WeakPolarHBondContact O-CG1 3.17Å; Y228-I232 PolarHBondContact O-N 2.91Å; Y228-T255 HydrophobicContact CD1-CG2 3.84Å; Y228-T255 HydrophobicContact CE1-CG2 3.65Å; Y228-V258 WeakPolarHBondContact OH-CB 3.34Å; Y228-V258 WeakPolarHBondContact OH-CG1 3.41Å; Y228-S259 WeakPolarHBondContact CD1-OG 3.33Å; Y228-S259 VanDerWaalsContact CE1-OG 3.23Å; Y228-S259 WeakPolarHBondContact CE1-OG 3.48Å; Y228-V262 HydrophobicContact CE2-CG2 4.29Å
229	L	86.5	Confident	85.1	Confident	93 Å²	93	59.6 Å²	59.6	49%	0.487	33%	0.332	S	S	.	.	H	α-helix	trans	-58.7	-48	175.7	-178.1	64.1	0	0	0	110.4	C225 L226 I231 I232 I233	C225-L229 WeakPolarHBondContact O-CB 3.46Å; C225-L229 PolarHBondContact O-N 3.46Å; L226-L229 PolarHBondContact O-N 3.37Å; L229-I231 PolarHBondContact O-N 2.92Å; L229-I232 PolarHBondContact O-N 3.49Å; L229-I233 HydrophobicContact CD1-CD1 4.25Å; L229-I233 HydrophobicContact CG-CD1 3.94Å; L229-I233 VanDerWaalsContact O-CG1 3.3Å; L229-I233 WeakPolarHBondContact O-CG1 2.95Å; L229-I233 PolarHBondContact O-N 2.94Å
230	L	88.9	Confident	83.2	Confident	78 Å²	78	63.5 Å²	63.5	41%	0.408	35%	0.352	S	S	.	.	H	α-helix	trans	-64.9	-37.5	177.6	-66.4	174.1	0	0	0	112.5	Y142 L226 C227 Y228 K234	Y142-L230 HydrophobicContact CD2-CB 3.96Å; Y142-L230 HydrophobicContact CD2-CD1 4.35Å; Y142-L230 HydrophobicContact CE2-CB 3.68Å; Y142-L230 HydrophobicContact CE2-CD1 3.69Å; Y142-L230 HydrophobicContact CE2-CG 4.34Å; L226-L230 WeakPolarHBondContact O-CB 3.47Å; L226-L230 VanDerWaalsContact O-CG 3.25Å; L226-L230 WeakPolarHBondContact O-CG 3.35Å; L226-L230 PolarHBondContact O-N 3.01Å; C227-L230 PolarHBondContact O-N 2.92Å; Y228-L230 VanDerWaalsContact C-N 3.33Å; Y228-L230 PolarHBondContact O-N 2.87Å; L230-K234 VanDerWaalsContact O-CB 3.29Å; L230-K234 WeakPolarHBondContact O-CB 3.31Å; L230-K234 PolarHBondContact O-N 3.38Å
231	I	86.3	Confident	81.2	Confident	4 Å²	4	73 Å²	73	2%	0.021	39%	0.387	C	S	.	.	H	α-helix	trans	-59.5	-48.8	171.9	-71.7	164	0	0	0	110.1	R141 Y142 V145 V146 C227 Y228 L229 K234 V235 T255	R141-I231 HydrophobicContact CB-CD1 4.32Å; Y142-I231 HydrophobicContact CD2-CG1 4.38Å; V145-I231 HydrophobicContact CG1-CG2 4.2Å; V146-I231 HydrophobicContact CG2-CG1 4.36Å; C227-I231 WeakPolarHBondContact O-CD1 3.43Å; C227-I231 WeakPolarHBondContact O-CG1 3.34Å; C227-I231 PolarHBondContact O-N 3.19Å; Y228-I231 HydrophobicContact CD1-CD1 4.24Å; Y228-I231 HydrophobicContact CE1-CD1 4.39Å; Y228-I231 WeakPolarHBondContact O-CB 3.13Å; Y228-I231 PolarHBondContact O-N 3.39Å; L229-I231 PolarHBondContact O-N 2.92Å; I231-K234 PolarHBondContact O-N 3.43Å; I231-V235 HydrophobicContact CG2-CG2 4.23Å; I231-V235 WeakPolarHBondContact O-CB 3.41Å; I231-V235 WeakPolarHBondContact O-CG2 3.36Å; I231-V235 PolarHBondContact O-N 3.42Å; I231-T255 HydrophobicContact CG2-CG2 3.98Å
232	I	83.1	Confident	79.1	Confident	86 Å²	86	79.2 Å²	79.2	44%	0.441	43%	0.426	S	S	.	.	H	α-helix	trans	-62.3	-47.6	-179.1	-69.2	165.2	0	0	0	110.6	Y228 L229 K234 V235 K236	Y228-I232 VanDerWaalsContact O-CG1 3.28Å; Y228-I232 WeakPolarHBondContact O-CG1 3.17Å; Y228-I232 PolarHBondContact O-N 2.91Å; L229-I232 PolarHBondContact O-N 3.49Å; I232-K234 VanDerWaalsContact C-N 3.34Å; I232-K234 PolarHBondContact O-N 2.97Å; I232-V235 PolarHBondContact O-N 2.97Å; I232-K236 HydrophobicContact CG2-CD 4.1Å; I232-K236 HydrophobicContact CG2-CG 4.43Å; I232-K236 WeakPolarHBondContact O-CB 3.21Å; I232-K236 WeakPolarHBondContact O-CG 2.77Å; I232-K236 PolarHBondContact O-N 3.22Å
233	I	83.8	Confident	77.1	Confident	92 Å²	92	77.9 Å²	77.9	47%	0.472	43%	0.431	S	S	.	.	H	α-helix	trans	-57.5	-48.9	177.3	-69.5	167.3	0	0	0	109.8	L229 V235 K236 S237	L229-I233 HydrophobicContact CD1-CD1 4.25Å; L229-I233 HydrophobicContact CG-CD1 3.94Å; L229-I233 VanDerWaalsContact O-CG1 3.3Å; L229-I233 WeakPolarHBondContact O-CG1 2.95Å; L229-I233 PolarHBondContact O-N 2.94Å; I233-V235 PolarHBondContact O-N 2.93Å; I233-K236 PolarHBondContact O-N 3.32Å; I233-S237 WeakPolarHBondContact O-CB 3.49Å; I233-S237 PolarHBondContact O-N 2.71Å
234	K	83.3	Confident	75.2	Confident	87 Å²	87	79.7 Å²	79.7	38%	0.378	45%	0.445	S	S	.	.	H	α-helix	trans	-63.1	-44.1	179.8	-175.1	63.1	174.4	176.6	0	111.8	V146 L230 I231 I232 K236 S237 S238	V146-K234 HydrophobicContact CB-CG 4.4Å; V146-K234 HydrophobicContact CG1-CB 4.47Å; V146-K234 HydrophobicContact CG1-CD 4.43Å; V146-K234 HydrophobicContact CG1-CG 4.21Å; V146-K234 HydrophobicContact CG2-CB 3.93Å; V146-K234 HydrophobicContact CG2-CG 4.13Å; L230-K234 VanDerWaalsContact O-CB 3.29Å; L230-K234 WeakPolarHBondContact O-CB 3.31Å; L230-K234 PolarHBondContact O-N 3.38Å; I231-K234 PolarHBondContact O-N 3.43Å; I232-K234 VanDerWaalsContact C-N 3.34Å; I232-K234 PolarHBondContact O-N 2.97Å; K234-K236 PolarHBondContact O-N 3.05Å; K234-S237 PolarHBondContact O-N 2.98Å; K234-S238 WeakPolarHBondContact O-CB 3.2Å; K234-S238 PolarHBondContact O-N 3.49Å; K234-S238 PolarHBondContact O-OG 3.36Å
235	V	78.1	Confident	73.7	Confident	52 Å²	52	84.4 Å²	84.4	32%	0.315	48%	0.478	S	S	.	.	H	α-helix	trans	-65	-38.6	-179.9	169.5	0	0	0	0	111.5	V145 I231 I232 I233	V145-V235 HydrophobicContact CG1-CG2 3.91Å; I231-V235 HydrophobicContact CG2-CG2 4.23Å; I231-V235 WeakPolarHBondContact O-CB 3.41Å; I231-V235 WeakPolarHBondContact O-CG2 3.36Å; I231-V235 PolarHBondContact O-N 3.42Å; I232-V235 PolarHBondContact O-N 2.97Å; I233-V235 PolarHBondContact O-N 2.93Å
236	K	77.1	Confident	72.1	Confident	166 Å²	166	89.6 Å²	89.6	72%	0.722	49%	0.493	S	S	*	.	H	α-helix	trans	-71.3	-45.9	175.8	-74.3	-174.8	174.6	-175.6	0	112.2	I232 I233 K234 S238 G239	I232-K236 HydrophobicContact CG2-CD 4.1Å; I232-K236 HydrophobicContact CG2-CG 4.43Å; I232-K236 WeakPolarHBondContact O-CB 3.21Å; I232-K236 WeakPolarHBondContact O-CG 2.77Å; I232-K236 PolarHBondContact O-N 3.22Å; I233-K236 PolarHBondContact O-N 3.32Å; K234-K236 PolarHBondContact O-N 3.05Å; K236-S238 PolarHBondContact O-N 3.33Å; K236-G239 PolarHBondContact O-N 3.16Å
237	S	76.9	Confident	70.4	Confident	96 Å²	96	92.3 Å²	92.3	67%	0.671	50%	0.497	S	S	*	.	H	α-helix	trans	-66.9	-33.1	179.8	170.3	0	0	0	0	112.9	I233 K234 G239	I233-S237 WeakPolarHBondContact O-CB 3.49Å; I233-S237 PolarHBondContact O-N 2.71Å; K234-S237 PolarHBondContact O-N 2.98Å; S237-G239 PolarHBondContact O-N 3.22Å
238	S	70	Confident	69.1	Low	42 Å²	42	95.8 Å²	95.8	29%	0.294	51%	0.511	S	S	.	.	T	Hydrogen-bonded Turn	trans	-77.5	26.9	177.6	-48.8	0	0	0	0	113.1	K234 K236 I240	K234-S238 WeakPolarHBondContact O-CB 3.2Å; K234-S238 PolarHBondContact O-N 3.49Å; K234-S238 PolarHBondContact O-OG 3.36Å; K236-S238 PolarHBondContact O-N 3.33Å; S238-I240 PolarHBondContact O-N 3.2Å
239	G	55.6	Low	68	Low	48 Å²	48	104.4 Å²	104.4	50%	0.495	54%	0.543	S	S	.	.	T	Hydrogen-bonded Turn	trans	-22.9	118.5	-170.5	0	0	0	0	0	113.7	K236 S237 R241	K236-G239 PolarHBondContact O-N 3.16Å; S237-G239 PolarHBondContact O-N 3.22Å; G239-R241 PolarHBondContact O-N 3.35Å
240	I	54.2	Low	66.7	Low	158 Å²	158	103 Å²	103	81%	0.81	54%	0.541	S	S	*	.	T	Hydrogen-bonded Turn	trans	14.8	60.8	173.1	-45.9	176.7	0	0	0	113.9	S238 V242	S238-I240 PolarHBondContact O-N 3.2Å; I240-V242 PolarHBondContact O-N 3.08Å
241	R	51	Low	65.6	Low	200 Å²	200	101.5 Å²	101.5	76%	0.755	53%	0.532	S	S	*	.			trans	-68.1	112.9	165.9	-72.6	-170.9	-172.6	-165.6	1	107.2	G239 G243 K248	G239-R241 PolarHBondContact O-N 3.35Å; R241-G243 VanDerWaalsContact C-N 3.31Å; R241-G243 PolarHBondContact O-N 2.94Å; R241-K248 PolarHBondContact O-NZ 2.98Å
242	V	47.6	Very low	64.8	Low	151 Å²	151	109.4 Å²	109.4	92%	0.915	56%	0.561	S	S	*	*	S	Bend	trans	-58.1	92.3	176.2	178.9	0	0	0	0	107.8	I240	I240-V242 PolarHBondContact O-N 3.08Å
243	G	51.6	Low	64.1	Low	49 Å²	49	107.8 Å²	107.8	51%	0.505	55%	0.551	S	S	.	*	S	Bend	trans	-175.7	99.5	-171.5	0	0	0	0	0	110.8	R241	R241-G243 VanDerWaalsContact C-N 3.31Å; R241-G243 PolarHBondContact O-N 2.94Å
244	S	55.1	Low	63.2	Low	79 Å²	79	105 Å²	105	55%	0.552	54%	0.539	S	S	*	.			trans	54.6	75.6	-179.5	-160.2	0	0	0	0	116.6	K246 R247 K248	S244-K246 PolarHBondContact O-N 2.89Å; S244-R247 PolarHBondContact O-N 3.29Å; S244-K248 PolarHBondContact O-N 2.74Å
245	S	59.1	Low	62.5	Low	100 Å²	100	101.9 Å²	101.9	70%	0.699	53%	0.527	S	S	*	.	H	α-helix	trans	-47.5	-39.5	170.8	168	0	0	0	0	113.5	R249	S245-R249 WeakPolarHBondContact O-CB 3.46Å; S245-R249 PolarHBondContact O-N 2.94Å
246	K	55.8	Low	62.5	Low	182 Å²	182	106.2 Å²	106.2	79%	0.791	54%	0.538	S	S	*	.	H	α-helix	trans	-65.5	-44.9	-179.7	-84.6	-176.9	176.5	175.6	0	113.3	S244 R249 S250	S244-K246 PolarHBondContact O-N 2.89Å; K246-R249 PolarHBondContact O-N 3.4Å; K246-S250 PolarHBondContact O-N 3.46Å; K246-S250 VanDerWaalsContact O-N 3.08Å
247	R	57.9	Low	62.2	Low	143 Å²	143	98.7 Å²	98.7	54%	0.54	51%	0.505	S	S	.	.	H	α-helix	trans	-65.8	-46.4	-180	-177.4	173.9	168.2	174.3	-2.7	111.1	S244 R249 S250 E251	S244-R247 PolarHBondContact O-N 3.29Å; R247-R249 VanDerWaalsContact C-N 3.33Å; R247-R249 PolarHBondContact O-N 2.9Å; R247-S250 PolarHBondContact O-N 3.16Å; R247-S250 PolarHBondContact O-OG 3.18Å; R247-E251 IonicContact CZ-OE1 3.99Å; R247-E251 IonicContact NE-OE1 3.14Å; R247-E251 PolarHBondContact NE-OE1 3.37Å; R247-E251 VanDerWaalsContact NE-OE1 3.14Å; R247-E251 IonicContact NH2-OE1 3.92Å; R247-E251 PolarHBondContact O-N 2.64Å
248	K	62.6	Low	61.9	Low	85 Å²	85	94.2 Å²	94.2	37%	0.37	47%	0.473	S	S	.	.	H	α-helix	trans	-61	-37.7	176.3	-69.8	-176.7	178.9	-176.5	0	112.8	R241 S244 R252	R241-K248 PolarHBondContact O-NZ 2.98Å; S244-K248 PolarHBondContact O-N 2.74Å; K248-R252 PolarHBondContact O-N 3.41Å
249	R	62.9	Low	62.2	Low	201 Å²	201	94.5 Å²	94.5	76%	0.758	48%	0.475	S	S	*	.	H	α-helix	trans	-65.2	-42	175.3	-173.4	175.7	-179.6	179.6	0	111.9	S245 K246 R247 K253	S245-R249 WeakPolarHBondContact O-CB 3.46Å; S245-R249 PolarHBondContact O-N 2.94Å; K246-R249 PolarHBondContact O-N 3.4Å; R247-R249 VanDerWaalsContact C-N 3.33Å; R247-R249 PolarHBondContact O-N 2.9Å; R249-K253 WeakPolarHBondContact O-CB 3.46Å; R249-K253 PolarHBondContact O-N 3.3Å; R249-K253 VanDerWaalsContact O-N 3.11Å
250	S	60.4	Low	63.4	Low	65 Å²	65	95.1 Å²	95.1	46%	0.455	47%	0.467	S	S	.	.	H	α-helix	trans	-65.6	-41.2	177.1	74.6	0	0	0	0	112.4	K246 R247 K253 V254	K246-S250 PolarHBondContact O-N 3.46Å; K246-S250 VanDerWaalsContact O-N 3.08Å; R247-S250 PolarHBondContact O-N 3.16Å; R247-S250 PolarHBondContact O-OG 3.18Å; S250-K253 WeakPolarHBondContact O-CB 3.4Å; S250-K253 PolarHBondContact O-N 2.94Å; S250-V254 WeakPolarHBondContact O-CG2 3.46Å; S250-V254 PolarHBondContact O-N 3.2Å; S250-V254 VanDerWaalsContact O-N 3.16Å
251	E	64.9	Low	64.5	Low	46 Å²	46	87.7 Å²	87.7	22%	0.215	43%	0.429	C	S	.	.	H	α-helix	trans	-67.1	-46.7	179.1	-72.1	172.4	-173.5	0	0	111.5	V145 R247 K253 V254 T255	V145-E251 HydrophobicContact CG2-CB 4.44Å; R247-E251 IonicContact CZ-OE1 3.99Å; R247-E251 IonicContact NE-OE1 3.14Å; R247-E251 PolarHBondContact NE-OE1 3.37Å; R247-E251 VanDerWaalsContact NE-OE1 3.14Å; R247-E251 IonicContact NH2-OE1 3.92Å; R247-E251 PolarHBondContact O-N 2.64Å; E251-K253 PolarHBondContact O-N 2.54Å; E251-V254 PolarHBondContact O-N 2.9Å; E251-T255 PolarHBondContact O-N 2.91Å; E251-T255 PolarHBondContact O-OG1 3.34Å; E251-T255 VanDerWaalsContact O-OG1 3.11Å
252	R	69.3	Low	65.8	Low	169 Å²	169	78.8 Å²	78.8	64%	0.638	40%	0.397	S	S	*	.	H	α-helix	trans	-57.2	-36.8	172.8	-83.2	-170.1	-176.7	-165.6	1.8	112.6	K248 T255 R256	K248-R252 PolarHBondContact O-N 3.41Å; R252-T255 PolarHBondContact O-N 3.08Å; R252-R256 WeakPolarHBondContact O-CB 3.48Å; R252-R256 PolarHBondContact O-N 2.87Å
253	K	68.8	Low	67.7	Low	52 Å²	52	74.4 Å²	74.4	23%	0.226	38%	0.376	C	S	.	.	H	α-helix	trans	-64.4	-44.6	178.4	-166.5	-179.2	-169.5	-159.8	0	111.5	R249 S250 E251 R256 M257 L315 E317	R249-K253 WeakPolarHBondContact O-CB 3.46Å; R249-K253 PolarHBondContact O-N 3.3Å; R249-K253 VanDerWaalsContact O-N 3.11Å; S250-K253 WeakPolarHBondContact O-CB 3.4Å; S250-K253 PolarHBondContact O-N 2.94Å; E251-K253 PolarHBondContact O-N 2.54Å; K253-R256 PolarHBondContact O-N 2.93Å; K253-M257 WeakPolarHBondContact O-CB 3.46Å; K253-M257 PolarHBondContact O-N 3.43Å; K253-L315 WeakPolarHBondContact CE-O 3.37Å; K253-L315 PolarHBondContact NZ-O 2.82Å; K253-E317 VanDerWaalsContact NZ-CD 3.31Å; K253-E317 VanDerWaalsContact NZ-CG 3.28Å; K253-E317 IonicContact NZ-OE1 2.63Å; K253-E317 PolarHBondContact NZ-OE1 3.11Å
254	V	64.9	Low	69.4	Low	35 Å²	35	73.8 Å²	73.8	21%	0.212	36%	0.363	C	S	.	.	H	α-helix	trans	-69.6	-40	177.7	-171.1	0	0	0	0	111	R141 S250 E251 R256 M257 V258	R141-V254 HydrophobicContact CG-CG1 4.42Å; S250-V254 WeakPolarHBondContact O-CG2 3.46Å; S250-V254 PolarHBondContact O-N 3.2Å; S250-V254 VanDerWaalsContact O-N 3.16Å; E251-V254 PolarHBondContact O-N 2.9Å; V254-R256 PolarHBondContact O-N 3.24Å; V254-M257 WeakPolarHBondContact O-CB 3.15Å; V254-M257 PolarHBondContact O-N 3.44Å; V254-V258 HydrophobicContact CG1-CG2 4.32Å; V254-V258 WeakPolarHBondContact O-CG2 3.5Å; V254-V258 PolarHBondContact O-N 3.31Å
255	T	69.9	Low	70.8	Confident	20 Å²	20	70.1 Å²	70.1	12%	0.123	34%	0.337	C	S	.	.	H	α-helix	trans	-57.9	-49.1	172.8	-56.4	0	0	0	0	111	Y228 I231 E251 R252 M257 V258 S259	Y228-T255 HydrophobicContact CD1-CG2 3.84Å; Y228-T255 HydrophobicContact CE1-CG2 3.65Å; I231-T255 HydrophobicContact CG2-CG2 3.98Å; E251-T255 PolarHBondContact O-N 2.91Å; E251-T255 PolarHBondContact O-OG1 3.34Å; E251-T255 VanDerWaalsContact O-OG1 3.11Å; R252-T255 PolarHBondContact O-N 3.08Å; T255-M257 VanDerWaalsContact C-N 3.28Å; T255-M257 PolarHBondContact O-N 3.08Å; T255-V258 PolarHBondContact O-N 3.11Å; T255-S259 PolarHBondContact O-N 3.25Å; T255-S259 PolarHBondContact O-OG 3.3Å
256	R	77	Confident	72.2	Confident	144 Å²	144	67.3 Å²	67.3	54%	0.543	32%	0.316	S	S	.	.	H	α-helix	trans	-57.6	-42.1	175.4	-172.3	-178.3	77.2	178.6	7.7	111.7	R252 K253 V254 S259 I260	R252-R256 WeakPolarHBondContact O-CB 3.48Å; R252-R256 PolarHBondContact O-N 2.87Å; K253-R256 PolarHBondContact O-N 2.93Å; V254-R256 PolarHBondContact O-N 3.24Å; R256-S259 PolarHBondContact O-N 3.13Å; R256-I260 HydrophobicContact CG-CD1 4.12Å; R256-I260 VanDerWaalsContact O-CG1 3.28Å; R256-I260 WeakPolarHBondContact O-CG1 3.16Å; R256-I260 PolarHBondContact O-N 3.4Å; R256-I260 VanDerWaalsContact O-N 3.07Å
257	M	72	Confident	73.9	Confident	8 Å²	8	65.3 Å²	65.3	4%	0.039	31%	0.307	C	S	.	.	H	α-helix	trans	-59.9	-52.4	178.3	-178.1	-174.8	101	0	0	111.3	K253 V254 T255 S259 I260 V261 Y312 L315	K253-M257 WeakPolarHBondContact O-CB 3.46Å; K253-M257 PolarHBondContact O-N 3.43Å; V254-M257 WeakPolarHBondContact O-CB 3.15Å; V254-M257 PolarHBondContact O-N 3.44Å; T255-M257 VanDerWaalsContact C-N 3.28Å; T255-M257 PolarHBondContact O-N 3.08Å; M257-S259 VanDerWaalsContact C-N 3.33Å; M257-S259 PolarHBondContact O-N 2.92Å; M257-I260 PolarHBondContact O-N 3.48Å; M257-V261 WeakPolarHBondContact O-CG2 3.41Å; M257-V261 PolarHBondContact O-N 3.33Å; M257-Y312 HydrophobicContact CE-CD1 3.89Å; M257-Y312 HydrophobicContact CE-CE1 3.82Å; M257-Y312 HydrophobicContact SD-CD1 4.16Å; M257-L315 HydrophobicContact CB-CB 4.02Å; M257-L315 HydrophobicContact CB-CD1 4.29Å; M257-L315 HydrophobicContact CG-CB 3.62Å; M257-L315 HydrophobicContact CG-CD1 3.85Å; M257-L315 HydrophobicContact CG-CG 4.35Å; M257-L315 HydrophobicContact SD-CB 4.08Å
258	V	69.9	Low	75.5	Confident	1 Å²	1	58.8 Å²	58.8	1%	0.006	28%	0.283	C	S	.	.	H	α-helix	trans	-69.9	-32.3	-176.8	-173.1	0	0	0	0	111.1	M137 R141 Y228 V254 T255 I260 V261 V262	M137-V258 HydrophobicContact CE-CG2 4.34Å; R141-V258 HydrophobicContact CG-CG2 4.43Å; Y228-V258 WeakPolarHBondContact OH-CB 3.34Å; Y228-V258 WeakPolarHBondContact OH-CG1 3.41Å; V254-V258 HydrophobicContact CG1-CG2 4.32Å; V254-V258 WeakPolarHBondContact O-CG2 3.5Å; V254-V258 PolarHBondContact O-N 3.31Å; T255-V258 PolarHBondContact O-N 3.11Å; V258-I260 VanDerWaalsContact C-N 3.34Å; V258-I260 PolarHBondContact O-N 3.21Å; V258-V261 PolarHBondContact O-N 3.47Å; V258-V262 VanDerWaalsContact O-CG2 3.27Å; V258-V262 WeakPolarHBondContact O-CG2 3.38Å; V258-V262 PolarHBondContact O-N 3.05Å
259	S	75.3	Confident	76.8	Confident	48 Å²	48	55.7 Å²	55.7	34%	0.336	27%	0.269	S	S	.	.	H	α-helix	trans	-60.3	-40.4	170.3	-58.2	0	0	0	0	113	Y228 T255 R256 M257 V262 A263	Y228-S259 WeakPolarHBondContact CD1-OG 3.33Å; Y228-S259 VanDerWaalsContact CE1-OG 3.23Å; Y228-S259 WeakPolarHBondContact CE1-OG 3.48Å; T255-S259 PolarHBondContact O-N 3.25Å; T255-S259 PolarHBondContact O-OG 3.3Å; R256-S259 PolarHBondContact O-N 3.13Å; M257-S259 VanDerWaalsContact C-N 3.33Å; M257-S259 PolarHBondContact O-N 2.92Å; S259-V262 PolarHBondContact O-N 3.27Å; S259-A263 PolarHBondContact O-N 3.12Å
260	I	82	Confident	78.1	Confident	61 Å²	61	49.6 Å²	49.6	31%	0.313	25%	0.251	S	S	.	.	H	α-helix	trans	-65.6	-43.8	175.7	-66.1	163.8	0	0	0	110.2	R256 M257 V258 V262 A263 V264 L311 L315	R256-I260 HydrophobicContact CG-CD1 4.12Å; R256-I260 VanDerWaalsContact O-CG1 3.28Å; R256-I260 WeakPolarHBondContact O-CG1 3.16Å; R256-I260 PolarHBondContact O-N 3.4Å; R256-I260 VanDerWaalsContact O-N 3.07Å; M257-I260 PolarHBondContact O-N 3.48Å; V258-I260 VanDerWaalsContact C-N 3.34Å; V258-I260 PolarHBondContact O-N 3.21Å; I260-V262 VanDerWaalsContact C-N 3.28Å; I260-V262 PolarHBondContact O-N 3.48Å; I260-A263 PolarHBondContact O-N 3.41Å; I260-A263 VanDerWaalsContact O-N 3.15Å; I260-V264 HydrophobicContact CG2-CG2 4.46Å; I260-V264 WeakPolarHBondContact O-CG2 3.42Å; I260-V264 PolarHBondContact O-N 3.3Å; I260-L311 HydrophobicContact CG2-CD1 4.5Å; I260-L311 HydrophobicContact CG2-CD2 3.46Å; I260-L311 VanDerWaalsContact CG2-CD2 3.46Å; I260-L315 HydrophobicContact CB-CD1 4.31Å; I260-L315 HydrophobicContact CD1-CD1 3.82Å; I260-L315 HydrophobicContact CD1-CD2 3.88Å; I260-L315 HydrophobicContact CG2-CD1 4.34Å
261	V	76.9	Confident	79.5	Confident	2 Å²	2	48.3 Å²	48.3	1%	0.012	24%	0.241	C	C	.	.	H	α-helix	trans	-59.4	-41.4	177.5	-180	0	0	0	0	111.1	L134 M257 V258 V264 F265 L311	L134-V261 HydrophobicContact CD1-CG1 4.05Å; L134-V261 HydrophobicContact CD2-CB 4.39Å; L134-V261 HydrophobicContact CD2-CG1 3.34Å; L134-V261 HydrophobicContact CG-CG1 4.34Å; M257-V261 WeakPolarHBondContact O-CG2 3.41Å; M257-V261 PolarHBondContact O-N 3.33Å; V258-V261 PolarHBondContact O-N 3.47Å; V261-V264 PolarHBondContact O-N 2.88Å; V261-F265 PolarHBondContact O-N 3.44Å; V261-L311 HydrophobicContact CB-CD1 4.12Å; V261-L311 HydrophobicContact CG1-CD1 4.46Å; V261-L311 HydrophobicContact CG2-CB 4.25Å; V261-L311 HydrophobicContact CG2-CD1 3.6Å
262	V	79	Confident	80.6	Confident	14 Å²	14	48 Å²	48	9%	0.085	24%	0.239	C	C	.	.	H	α-helix	trans	-64.2	-43.3	175.1	171.1	0	0	0	0	111.7	L221 I224 Y228 V258 S259 I260 V264 F265 V266	L221-V262 HydrophobicContact CD2-CG1 4.09Å; I224-V262 HydrophobicContact CD1-CG2 4.37Å; I224-V262 HydrophobicContact CG2-CB 4.19Å; I224-V262 HydrophobicContact CG2-CG1 3.65Å; I224-V262 HydrophobicContact CG2-CG2 3.48Å; I224-V262 VanDerWaalsContact CG2-CG2 3.48Å; Y228-V262 HydrophobicContact CE2-CG2 4.29Å; V258-V262 VanDerWaalsContact O-CG2 3.27Å; V258-V262 WeakPolarHBondContact O-CG2 3.38Å; V258-V262 PolarHBondContact O-N 3.05Å; S259-V262 PolarHBondContact O-N 3.27Å; I260-V262 VanDerWaalsContact C-N 3.28Å; I260-V262 PolarHBondContact O-N 3.48Å; V262-V264 VanDerWaalsContact C-N 3.31Å; V262-V264 PolarHBondContact O-N 3.02Å; V262-F265 WeakPolarHBondContact O-CB 3.26Å; V262-F265 PolarHBondContact O-N 2.87Å; V262-V266 WeakPolarHBondContact O-CG2 3.45Å; V262-V266 PolarHBondContact O-N 3.37Å
263	A	85.5	Confident	81.4	Confident	59 Å²	59	40.1 Å²	40.1	49%	0.488	21%	0.209	S	C	.	.	H	α-helix	trans	-62	-40.2	178.1	0	0	0	0	0	111.8	S259 I260 V266 F267	S259-A263 PolarHBondContact O-N 3.12Å; I260-A263 PolarHBondContact O-N 3.41Å; I260-A263 VanDerWaalsContact O-N 3.15Å; A263-V266 PolarHBondContact O-N 2.03Å; A263-F267 WeakPolarHBondContact O-CB 3.49Å; A263-F267 PolarHBondContact O-N 2.87Å
264	V	87.6	Confident	82.2	Confident	36 Å²	36	41.1 Å²	41.1	22%	0.218	22%	0.22	C	C	.	.	H	α-helix	trans	-64.7	-43.6	174.4	173.7	0	0	0	0	111.1	I260 V261 V262 V266 F267 C268 A307 L311	I260-V264 HydrophobicContact CG2-CG2 4.46Å; I260-V264 WeakPolarHBondContact O-CG2 3.42Å; I260-V264 PolarHBondContact O-N 3.3Å; V261-V264 PolarHBondContact O-N 2.88Å; V262-V264 VanDerWaalsContact C-N 3.31Å; V262-V264 PolarHBondContact O-N 3.02Å; V264-V266 VanDerWaalsContact C-N 3.34Å; V264-V266 PolarHBondContact O-N 3.48Å; V264-F267 PolarHBondContact O-N 3.41Å; V264-C268 WeakPolarHBondContact O-CB 3Å; V264-C268 PolarHBondContact O-N 3.08Å; V264-C268 PolarHBondContact O-SG 3.19Å; V264-C268 VanDerWaalsContact O-SG 3.4Å; V264-A307 HydrophobicContact CG1-CB 3.58Å; V264-L311 HydrophobicContact CB-CD1 4.41Å; V264-L311 HydrophobicContact CG2-CD1 4.14Å
265	F	85.7	Confident	83.1	Confident	1 Å²	1	41.1 Å²	41.1	0%	0.004	22%	0.217	C	C	.	.	H	α-helix	trans	-57.2	-46.9	175.1	178.3	-88.9	0	0	0	111.9	I131 L134 F217 V261 V262 C268 W269 N304	I131-F265 HydrophobicContact CB-CE1 4.37Å; I131-F265 HydrophobicContact CB-CE2 3.8Å; I131-F265 HydrophobicContact CB-CZ 3.62Å; I131-F265 HydrophobicContact CD1-CD1 3.63Å; I131-F265 HydrophobicContact CD1-CD2 4.17Å; I131-F265 HydrophobicContact CD1-CE1 3.32Å; I131-F265 HydrophobicContact CD1-CE2 3.9Å; I131-F265 HydrophobicContact CD1-CG 4.05Å; I131-F265 HydrophobicContact CD1-CZ 3.48Å; I131-F265 VanDerWaalsContact CD1-CZ 3.48Å; I131-F265 HydrophobicContact CG1-CE1 3.79Å; I131-F265 HydrophobicContact CG1-CE2 4.12Å; I131-F265 HydrophobicContact CG1-CZ 3.54Å; L134-F265 HydrophobicContact CD1-CB 4.04Å; L134-F265 HydrophobicContact CD1-CD2 4.11Å; L134-F265 HydrophobicContact CD1-CG 4.18Å; F217-F265 AromaticContact CD2-CE1 3.91Å; F217-F265 HydrophobicContact CD2-CE1 3.91Å; F217-F265 HydrophobicContact CE2-CE1 4.28Å; V261-F265 PolarHBondContact O-N 3.44Å; V262-F265 WeakPolarHBondContact O-CB 3.26Å; V262-F265 PolarHBondContact O-N 2.87Å; F265-C268 PolarHBondContact O-N 2.98Å; F265-W269 AromaticContact CD2-CD1 3.42Å; F265-W269 VanDerWaalsContact CD2-CD1 3.42Å; F265-W269 HydrophobicContact CD2-CG 4.37Å; F265-W269 AromaticContact CD2-NE1 3.8Å; F265-W269 HydrophobicContact CE1-CB 4.33Å; F265-W269 HydrophobicContact CE1-CG 4.44Å; F265-W269 AromaticContact CE2-CD1 3.27Å; F265-W269 HydrophobicContact CE2-CD2 4.5Å; F265-W269 AromaticContact CE2-CG 3.92Å; F265-W269 HydrophobicContact CE2-CG 3.92Å; F265-W269 AromaticContact CE2-NE1 3.5Å; F265-W269 HydrophobicContact CZ-CB 4.27Å; F265-W269 AromaticContact CZ-CD1 3.74Å; F265-W269 AromaticContact CZ-CG 3.95Å; F265-W269 HydrophobicContact CZ-CG 3.95Å; F265-W269 WeakPolarHBondContact O-CB 3.48Å; F265-W269 PolarHBondContact O-N 3.14Å; F265-N304 WeakPolarHBondContact CA-OD1 3.42Å
266	V	88.4	Confident	83.5	Confident	42 Å²	42	40.4 Å²	40.4	26%	0.255	21%	0.213	S	C	.	.	H	α-helix	trans	-60.5	-47.6	176.8	174.2	0	0	0	0	110.7	F217 L221 V262 A263 V264 C268 W269 L270	F217-V266 HydrophobicContact CZ-CG1 4.41Å; L221-V266 HydrophobicContact CD1-CG2 3.95Å; L221-V266 HydrophobicContact CD2-CG2 3.34Å; L221-V266 HydrophobicContact CG-CG2 4.31Å; V262-V266 WeakPolarHBondContact O-CG2 3.45Å; V262-V266 PolarHBondContact O-N 3.37Å; A263-V266 PolarHBondContact O-N 2.03Å; V264-V266 VanDerWaalsContact C-N 3.34Å; V264-V266 PolarHBondContact O-N 3.48Å; V266-C268 VanDerWaalsContact C-N 3.27Å; V266-C268 PolarHBondContact O-N 3.33Å; V266-W269 PolarHBondContact O-N 3.08Å; V266-L270 HydrophobicContact CG1-CB 4.24Å; V266-L270 HydrophobicContact CG1-CD2 4.29Å; V266-L270 WeakPolarHBondContact O-CB 3.5Å; V266-L270 PolarHBondContact O-N 3.47Å
267	F	91.6	Very high	83.6	Confident	140 Å²	140	35.8 Å²	35.8	61%	0.614	20%	0.2	S	C	*	.	H	α-helix	trans	-60	-39.4	179.2	179.6	-100.2	0	0	0	112.2	A263 V264 P271 L300	A263-F267 WeakPolarHBondContact O-CB 3.49Å; A263-F267 PolarHBondContact O-N 2.87Å; V264-F267 PolarHBondContact O-N 3.41Å; F267-P271 VanDerWaalsContact O-CD 3.22Å; F267-P271 WeakPolarHBondContact O-CD 3.01Å; F267-L300 HydrophobicContact CD1-CD1 4.27Å; F267-L300 HydrophobicContact CE1-CD1 3.85Å; F267-L300 HydrophobicContact CE1-CD2 4.28Å
268	C	90.4	Very high	83.8	Confident	5 Å²	5	37.1 Å²	37.1	3%	0.034	21%	0.209	C	C	.	.	H	α-helix	trans	-74.6	-39.6	-178.8	-74.4	0	0	0	0	113.6	V264 F265 V266 L300 N304	V264-C268 WeakPolarHBondContact O-CB 3Å; V264-C268 PolarHBondContact O-N 3.08Å; V264-C268 PolarHBondContact O-SG 3.19Å; V264-C268 VanDerWaalsContact O-SG 3.4Å; F265-C268 PolarHBondContact O-N 2.98Å; V266-C268 VanDerWaalsContact C-N 3.27Å; V266-C268 PolarHBondContact O-N 3.33Å; C268-L300 WeakPolarHBondContact CB-O 3.36Å; C268-L300 PolarHBondContact SG-O 3.35Å; C268-L300 VanDerWaalsContact SG-O 3.33Å; C268-N304 HydrophobicContact CB-CB 3.77Å
269	W	89.9	Confident	83.8	Confident	21 Å²	21	37.8 Å²	37.8	8%	0.08	21%	0.213	C	C	.	.	H	α-helix	trans	-101.7	-26.9	-170.2	-74.8	95.1	0	0	0	114.7	Q127 F217 F265 V266 P271 F272 Y273	Q127-W269 HydrophobicContact CB-CH2 3.68Å; Q127-W269 HydrophobicContact CB-CZ2 4.01Å; Q127-W269 HydrophobicContact CB-CZ3 4.32Å; Q127-W269 HydrophobicContact CG-CE3 4.22Å; Q127-W269 HydrophobicContact CG-CH2 3.5Å; Q127-W269 VanDerWaalsContact CG-CH2 3.5Å; Q127-W269 HydrophobicContact CG-CZ2 3.93Å; Q127-W269 HydrophobicContact CG-CZ3 3.66Å; F217-W269 HydrophobicContact CD2-CB 4.22Å; F217-W269 HydrophobicContact CE2-CB 4.18Å; F265-W269 AromaticContact CD2-CD1 3.42Å; F265-W269 VanDerWaalsContact CD2-CD1 3.42Å; F265-W269 HydrophobicContact CD2-CG 4.37Å; F265-W269 AromaticContact CD2-NE1 3.8Å; F265-W269 HydrophobicContact CE1-CB 4.33Å; F265-W269 HydrophobicContact CE1-CG 4.44Å; F265-W269 AromaticContact CE2-CD1 3.27Å; F265-W269 HydrophobicContact CE2-CD2 4.5Å; F265-W269 AromaticContact CE2-CG 3.92Å; F265-W269 HydrophobicContact CE2-CG 3.92Å; F265-W269 AromaticContact CE2-NE1 3.5Å; F265-W269 HydrophobicContact CZ-CB 4.27Å; F265-W269 AromaticContact CZ-CD1 3.74Å; F265-W269 AromaticContact CZ-CG 3.95Å; F265-W269 HydrophobicContact CZ-CG 3.95Å; F265-W269 WeakPolarHBondContact O-CB 3.48Å; F265-W269 PolarHBondContact O-N 3.14Å; V266-W269 PolarHBondContact O-N 3.08Å; W269-P271 VanDerWaalsContact C-CD 3.5Å; W269-F272 HydrophobicContact CE3-CD1 4.17Å; W269-F272 HydrophobicContact CZ3-CD1 4.27Å; W269-F272 WeakPolarHBondContact O-CB 3.44Å; W269-F272 PolarHBondContact O-N 3.08Å; W269-F272 VanDerWaalsContact O-N 3.17Å; W269-Y273 HydrophobicContact CB-CD2 4.29Å; W269-Y273 HydrophobicContact CB-CE2 4.05Å; W269-Y273 HydrophobicContact CE3-CE2 4.14Å; W269-Y273 WeakPolarHBondContact O-CD2 3.31Å; W269-Y273 PolarHBondContact O-N 2.85Å; W269-Y273 VanDerWaalsContact O-N 3.17Å
270	L	90.2	Very high	83.4	Confident	73 Å²	73	37.3 Å²	37.3	38%	0.382	21%	0.208	S	C	.	.	H	α-helix	trans	-56.1	-46	179.6	178.6	65.1	0	0	0	112.4	F217 V266 F272 Y273 V274	F217-L270 HydrophobicContact CE1-CD1 3.78Å; F217-L270 HydrophobicContact CE2-CB 4.19Å; F217-L270 HydrophobicContact CZ-CB 3.77Å; F217-L270 HydrophobicContact CZ-CD1 3.63Å; F217-L270 HydrophobicContact CZ-CG 4.27Å; V266-L270 HydrophobicContact CG1-CB 4.24Å; V266-L270 HydrophobicContact CG1-CD2 4.29Å; V266-L270 WeakPolarHBondContact O-CB 3.5Å; V266-L270 PolarHBondContact O-N 3.47Å; L270-F272 VanDerWaalsContact C-N 3.25Å; L270-F272 PolarHBondContact O-N 2.97Å; L270-Y273 PolarHBondContact O-N 2.89Å; L270-V274 HydrophobicContact CD1-CG2 3.87Å; L270-V274 HydrophobicContact CG-CG2 4.13Å; L270-V274 VanDerWaalsContact O-CG2 3.31Å; L270-V274 WeakPolarHBondContact O-CG2 3.26Å; L270-V274 PolarHBondContact O-N 3.03Å
271	P	90.3	Very high	82.9	Confident	38 Å²	38	38.6 Å²	38.6	25%	0.247	22%	0.219	C	C	.	.	H	α-helix	trans	-59.8	-38.5	179.9	-23.8	36.2	0	0	0	112	F267 W269 V274 F275 V297 L300	F267-P271 VanDerWaalsContact O-CD 3.22Å; F267-P271 WeakPolarHBondContact O-CD 3.01Å; W269-P271 VanDerWaalsContact C-CD 3.5Å; P271-V274 PolarHBondContact O-N 3.44Å; P271-F275 WeakPolarHBondContact O-CB 3.37Å; P271-F275 WeakPolarHBondContact O-CD2 3.4Å; P271-F275 PolarHBondContact O-N 2.7Å; P271-V297 VanDerWaalsContact C-CG1 3.49Å; P271-V297 HydrophobicContact CB-CB 4.47Å; P271-V297 HydrophobicContact CB-CG1 3.88Å; P271-V297 HydrophobicContact CB-CG2 3.82Å; P271-L300 HydrophobicContact CG-CD2 4.15Å
272	F	87.6	Confident	82.3	Confident	38 Å²	38	41.2 Å²	41.2	17%	0.167	25%	0.246	C	C	.	.	H	α-helix	trans	-61.4	-49.4	177.7	175	-94.3	0	0	0	111.4	W269 L270 F275 N276 F294 V297 V298	W269-F272 HydrophobicContact CE3-CD1 4.17Å; W269-F272 HydrophobicContact CZ3-CD1 4.27Å; W269-F272 WeakPolarHBondContact O-CB 3.44Å; W269-F272 PolarHBondContact O-N 3.08Å; W269-F272 VanDerWaalsContact O-N 3.17Å; L270-F272 VanDerWaalsContact C-N 3.25Å; L270-F272 PolarHBondContact O-N 2.97Å; F272-F275 PolarHBondContact O-N 3.23Å; F272-N276 VanDerWaalsContact CE1-ND2 3.3Å; F272-N276 WeakPolarHBondContact CE1-ND2 3.46Å; F272-N276 WeakPolarHBondContact CE2-ND2 3.28Å; F272-N276 WeakPolarHBondContact CZ-ND2 3.32Å; F272-N276 PolarHBondContact O-N 3.15Å; F272-N276 PolarHBondContact O-ND2 3.18Å; F272-F294 HydrophobicContact CE2-CZ 4.45Å; F272-V297 HydrophobicContact CB-CG1 3.76Å; F272-V298 HydrophobicContact CD2-CG2 4.21Å; F272-V298 HydrophobicContact CE2-CG2 4.26Å
273	Y	86	Confident	81.3	Confident	4 Å²	4	44.2 Å²	44.2	2%	0.016	27%	0.268	C	S	.	.	H	α-helix	trans	-67.9	-37.5	179.2	-71	-68.7	0	0	0	113.1	Q127 F213 G216 F217 W269 L270 N276 V277	Q127-Y273 PolarHBondContact NE2-OH 3.34Å; F213-Y273 HydrophobicContact CB-CD1 3.99Å; F213-Y273 HydrophobicContact CB-CE1 4.27Å; F213-Y273 AromaticContact CD2-CD1 3.75Å; F213-Y273 HydrophobicContact CD2-CD1 3.75Å; F213-Y273 HydrophobicContact CD2-CE1 4.48Å; F213-Y273 AromaticContact CD2-CG 3.76Å; F213-Y273 HydrophobicContact CD2-CG 3.76Å; F213-Y273 HydrophobicContact CE2-CG 4.44Å; F213-Y273 HydrophobicContact CG-CD1 4.39Å; G216-Y273 WeakPolarHBondContact CA-OH 3.37Å; G216-Y273 PolarHBondContact O-OH 3.12Å; F217-Y273 HydrophobicContact CB-CD2 3.76Å; F217-Y273 HydrophobicContact CB-CE1 4.4Å; F217-Y273 HydrophobicContact CB-CE2 3.42Å; F217-Y273 VanDerWaalsContact CB-CE2 3.42Å; F217-Y273 HydrophobicContact CB-CG 4.38Å; F217-Y273 HydrophobicContact CD1-CD2 4.37Å; F217-Y273 AromaticContact CD2-CD2 3.55Å; F217-Y273 HydrophobicContact CD2-CD2 3.55Å; F217-Y273 AromaticContact CD2-CE2 3.51Å; F217-Y273 HydrophobicContact CD2-CE2 3.51Å; F217-Y273 HydrophobicContact CE2-CD2 4.2Å; F217-Y273 HydrophobicContact CE2-CE2 4.48Å; F217-Y273 AromaticContact CG-CD2 3.64Å; F217-Y273 HydrophobicContact CG-CD2 3.64Å; F217-Y273 AromaticContact CG-CE2 3.69Å; F217-Y273 HydrophobicContact CG-CE2 3.69Å; F217-Y273 HydrophobicContact CG-CG 4.43Å; W269-Y273 HydrophobicContact CB-CD2 4.29Å; W269-Y273 HydrophobicContact CB-CE2 4.05Å; W269-Y273 HydrophobicContact CE3-CE2 4.14Å; W269-Y273 WeakPolarHBondContact O-CD2 3.31Å; W269-Y273 PolarHBondContact O-N 2.85Å; W269-Y273 VanDerWaalsContact O-N 3.17Å; L270-Y273 PolarHBondContact O-N 2.89Å; Y273-N276 PolarHBondContact O-N 2.94Å; Y273-V277 WeakPolarHBondContact O-CG2 3.33Å; Y273-V277 PolarHBondContact O-N 2.82Å
274	V	86.3	Confident	80.1	Confident	73 Å²	73	43.6 Å²	43.6	44%	0.442	26%	0.256	S	S	.	.	H	α-helix	trans	-59.8	-48.3	174.9	170.8	0	0	0	0	110	L270 P271 N276 V277 T278	L270-V274 HydrophobicContact CD1-CG2 3.87Å; L270-V274 HydrophobicContact CG-CG2 4.13Å; L270-V274 VanDerWaalsContact O-CG2 3.31Å; L270-V274 WeakPolarHBondContact O-CG2 3.26Å; L270-V274 PolarHBondContact O-N 3.03Å; P271-V274 PolarHBondContact O-N 3.44Å; V274-N276 VanDerWaalsContact C-N 3.33Å; V274-N276 PolarHBondContact O-N 3.34Å; V274-V277 PolarHBondContact O-N 3.41Å; V274-T278 HydrophobicContact CG1-CG2 4.28Å; V274-T278 WeakPolarHBondContact O-CG2 3.44Å; V274-T278 PolarHBondContact O-N 3.47Å; V274-T278 PolarHBondContact O-OG1 3.27Å
275	F	83.2	Confident	78.9	Confident	35 Å²	35	46.7 Å²	46.7	15%	0.154	28%	0.28	C	S	.	.	H	α-helix	trans	-58.4	-41.4	176.9	-101	-81.1	0	0	0	113.3	P271 F272 T278 S279 L290 T293 F294 V297	P271-F275 WeakPolarHBondContact O-CB 3.37Å; P271-F275 WeakPolarHBondContact O-CD2 3.4Å; P271-F275 PolarHBondContact O-N 2.7Å; F272-F275 PolarHBondContact O-N 3.23Å; F275-T278 WeakPolarHBondContact CA-OG1 3.26Å; F275-T278 PolarHBondContact O-OG1 2.86Å; F275-T278 VanDerWaalsContact O-OG1 3.1Å; F275-S279 WeakPolarHBondContact O-CB 3.25Å; F275-S279 PolarHBondContact O-N 3.25Å; F275-S279 VanDerWaalsContact O-N 3.08Å; F275-S279 PolarHBondContact O-OG 2.81Å; F275-L290 HydrophobicContact CE1-CD2 3.68Å; F275-L290 HydrophobicContact CZ-CD2 4.16Å; F275-T293 HydrophobicContact CE2-CG2 3.77Å; F275-T293 HydrophobicContact CZ-CG2 3.47Å; F275-T293 VanDerWaalsContact CZ-CG2 3.47Å; F275-F294 HydrophobicContact CB-CD2 4.02Å; F275-F294 HydrophobicContact CB-CE2 4.34Å; F275-F294 HydrophobicContact CD1-CB 4.48Å; F275-F294 HydrophobicContact CD1-CD2 4.12Å; F275-F294 HydrophobicContact CG-CD2 4.15Å; F275-V297 HydrophobicContact CD2-CB 4.46Å; F275-V297 HydrophobicContact CD2-CG1 4.34Å; F275-V297 HydrophobicContact CD2-CG2 3.9Å; F275-V297 HydrophobicContact CE2-CG2 3.85Å
276	N	78.6	Confident	77.8	Confident	6 Å²	6	50.6 Å²	50.6	3%	0.032	30%	0.303	C	S	.	.	H	α-helix	trans	-72.2	-30.6	179.8	-76.2	-68.1	0	0	0	113.1	M209 F272 Y273 V274 S279 V280	M209-N276 HydrophobicContact CE-CB 4Å; M209-N276 WeakPolarHBondContact CE-OD1 3.41Å; M209-N276 HydrophobicContact SD-CB 3.81Å; F272-N276 VanDerWaalsContact CE1-ND2 3.3Å; F272-N276 WeakPolarHBondContact CE1-ND2 3.46Å; F272-N276 WeakPolarHBondContact CE2-ND2 3.28Å; F272-N276 WeakPolarHBondContact CZ-ND2 3.32Å; F272-N276 PolarHBondContact O-N 3.15Å; F272-N276 PolarHBondContact O-ND2 3.18Å; Y273-N276 PolarHBondContact O-N 2.94Å; V274-N276 VanDerWaalsContact C-N 3.33Å; V274-N276 PolarHBondContact O-N 3.34Å; N276-S279 PolarHBondContact O-OG 3.49Å; N276-V280 WeakPolarHBondContact O-CG2 3.44Å
277	V	78.3	Confident	76.9	Confident	47 Å²	47	51.3 Å²	51.3	29%	0.285	31%	0.308	S	S	.	.	H	α-helix	trans	-76.9	-39.1	175.6	171.8	0	0	0	0	111.2	Y273 V274 T281	Y273-V277 WeakPolarHBondContact O-CG2 3.33Å; Y273-V277 PolarHBondContact O-N 2.82Å; V274-V277 PolarHBondContact O-N 3.41Å; V277-T281 WeakPolarHBondContact O-CG2 3.49Å; V277-T281 PolarHBondContact O-N 3.42Å; V277-T281 PolarHBondContact O-OG1 3.37Å
278	T	76.9	Confident	75.7	Confident	36 Å²	36	47 Å²	47	22%	0.221	29%	0.294	C	S	.	.	H	α-helix	trans	-71.2	-31	179.6	53.4	0	0	0	0	112.8	V274 F275 T281 S283 I284	V274-T278 HydrophobicContact CG1-CG2 4.28Å; V274-T278 WeakPolarHBondContact O-CG2 3.44Å; V274-T278 PolarHBondContact O-N 3.47Å; V274-T278 PolarHBondContact O-OG1 3.27Å; F275-T278 WeakPolarHBondContact CA-OG1 3.26Å; F275-T278 PolarHBondContact O-OG1 2.86Å; F275-T278 VanDerWaalsContact O-OG1 3.1Å; T278-T281 WeakPolarHBondContact CA-OG1 3.5Å; T278-T281 PolarHBondContact O-OG1 3.19Å; T278-S283 WeakPolarHBondContact CA-OG 3.04Å; T278-S283 WeakPolarHBondContact CB-OG 3.43Å; T278-S283 PolarHBondContact O-N 3.47Å; T278-S283 PolarHBondContact O-OG 2.93Å; T278-I284 HydrophobicContact CG2-CD1 4.47Å; T278-I284 WeakPolarHBondContact OG1-CD1 3.45Å
279	S	70.3	Confident	74.9	Confident	14 Å²	14	52.4 Å²	52.4	10%	0.098	32%	0.321	C	S	.	.	H	α-helix	trans	-66.1	-40.5	175.3	64.6	0	0	0	0	112.5	F275 N276	F275-S279 WeakPolarHBondContact O-CB 3.25Å; F275-S279 PolarHBondContact O-N 3.25Å; F275-S279 VanDerWaalsContact O-N 3.08Å; F275-S279 PolarHBondContact O-OG 2.81Å; N276-S279 PolarHBondContact O-OG 3.49Å
280	V	67.9	Low	74.2	Confident	38 Å²	38	53.2 Å²	53.2	23%	0.23	33%	0.327	C	S	.	.	H	α-helix	trans	-74.4	-27.7	178.9	175.2	0	0	0	0	112.9	Y205 T206 N276 G282	Y205-V280 HydrophobicContact CD1-CG2 4.1Å; Y205-V280 HydrophobicContact CE1-CG2 3.59Å; T206-V280 HydrophobicContact CG2-CG1 3.93Å; N276-V280 WeakPolarHBondContact O-CG2 3.44Å; V280-G282 PolarHBondContact O-N 3.35Å
281	T	70.1	Confident	73.2	Confident	89 Å²	89	52 Å²	52	55%	0.546	32%	0.317	S	S	.	.	T	Hydrogen-bonded Turn	trans	-83.2	8.4	-179.8	47.2	0	0	0	0	113.5	V277 T278 S283	V277-T281 WeakPolarHBondContact O-CG2 3.49Å; V277-T281 PolarHBondContact O-N 3.42Å; V277-T281 PolarHBondContact O-OG1 3.37Å; T278-T281 WeakPolarHBondContact CA-OG1 3.5Å; T278-T281 PolarHBondContact O-OG1 3.19Å; T281-S283 PolarHBondContact O-N 2.71Å
282	G	63.8	Low	72.4	Confident	56 Å²	56	51.5 Å²	51.5	58%	0.577	32%	0.315	S	S	*	.	T	Hydrogen-bonded Turn	trans	67.4	15.9	177.8	0	0	0	0	0	114.3	V280 I284	V280-G282 PolarHBondContact O-N 3.35Å; G282-I284 PolarHBondContact O-N 3.4Å
283	S	58.3	Low	72	Confident	77 Å²	77	52.3 Å²	52.3	54%	0.538	32%	0.323	S	S	.	.			trans	-85.1	-4.1	-169.8	64.2	0	0	0	0	114.7	T278 T281	T278-S283 WeakPolarHBondContact CA-OG 3.04Å; T278-S283 WeakPolarHBondContact CB-OG 3.43Å; T278-S283 PolarHBondContact O-N 3.47Å; T278-S283 PolarHBondContact O-OG 2.93Å; T281-S283 PolarHBondContact O-N 2.71Å
284	I	61.3	Low	71.8	Confident	46 Å²	46	52.8 Å²	52.8	24%	0.236	33%	0.325	C	S	.	.			trans	-138.5	122	-169.9	-58.7	-175.7	0	0	0	111.6	T278 G282 L290	T278-I284 HydrophobicContact CG2-CD1 4.47Å; T278-I284 WeakPolarHBondContact OG1-CD1 3.45Å; G282-I284 PolarHBondContact O-N 3.4Å; I284-L290 HydrophobicContact CD1-CD2 4.42Å; I284-L290 HydrophobicContact CG2-CD1 3.42Å; I284-L290 VanDerWaalsContact CG2-CD1 3.42Å; I284-L290 HydrophobicContact CG2-CD2 3.57Å; I284-L290 HydrophobicContact CG2-CG 4.09Å
285	S	61.3	Low	71.4	Confident	102 Å²	102	50.1 Å²	50.1	71%	0.713	31%	0.311	S	S	*	.			trans	-79.7	137.1	168.3	-52.3	0	0	0	0	111.2	T287 L290	S285-T287 PolarHBondContact O-N 2.69Å; S285-L290 WeakPolarHBondContact O-CD1 3.4Å
286	T	63.2	Low	71.4	Confident	82 Å²	82	53.6 Å²	53.6	50%	0.503	33%	0.326	S	S	.	.			trans	-67.6	100.1	179.9	46.2	0	0	0	0	112.1	L18	L18-T286 HydrophobicContact CD1-CG2 4.43Å; L18-T286 HydrophobicContact CD2-CG2 3.51Å; L18-T286 HydrophobicContact CG-CG2 3.65Å
287	T	70.4	Confident	71.8	Confident	58 Å²	58	53.7 Å²	53.7	36%	0.356	33%	0.327	S	S	.	.			trans	-104	155.7	169	72.7	0	0	0	0	111.1	S285 I289 L290 R291	S285-T287 PolarHBondContact O-N 2.69Å; T287-I289 PolarHBondContact O-N 2.73Å; T287-L290 HydrophobicContact CG2-CD1 4.22Å; T287-L290 WeakPolarHBondContact O-CB 3.02Å; T287-L290 PolarHBondContact O-N 3.23Å; T287-L290 WeakPolarHBondContact OG1-CD1 3.49Å; T287-L290 PolarHBondContact OG1-N 3.43Å; T287-R291 PolarHBondContact O-N 3.05Å; T287-R291 VanDerWaalsContact O-N 3.08Å
288	P	66.6	Low	72.1	Confident	48 Å²	48	52.3 Å²	52.3	31%	0.312	32%	0.319	S	S	.	.	H	α-helix	trans	-54.7	-35.6	174.5	-26.9	34.7	0	0	0	113.3	F39 R291 S292	F39-P288 HydrophobicContact CE1-CB 4.39Å; P288-R291 PolarHBondContact O-N 3.25Å; P288-S292 PolarHBondContact O-N 3.42Å; P288-S292 VanDerWaalsContact O-N 3.1Å; P288-S292 PolarHBondContact O-OG 3.1Å
289	I	71.8	Confident	72.7	Confident	119 Å²	119	51.1 Å²	51.1	61%	0.61	31%	0.311	S	S	*	.	H	α-helix	trans	-64.9	-43.7	176.8	-62.6	169.9	0	0	0	110.9	T287 R291 S292 T293	T287-I289 PolarHBondContact O-N 2.73Å; I289-R291 VanDerWaalsContact C-N 3.28Å; I289-R291 PolarHBondContact O-N 3.08Å; I289-S292 PolarHBondContact O-N 3.27Å; I289-T293 WeakPolarHBondContact O-CB 3.35Å; I289-T293 PolarHBondContact O-N 3.38Å; I289-T293 PolarHBondContact O-OG1 3.05Å
290	L	75.3	Confident	73.6	Confident	38 Å²	38	51.7 Å²	51.7	20%	0.199	31%	0.313	C	S	.	.	H	α-helix	trans	-63.6	-34.6	176.4	-87.8	150.9	0	0	0	111.7	F22 F275 I284 S285 T287 T293 F294	F22-L290 HydrophobicContact CE1-CB 4.45Å; F22-L290 WeakPolarHBondContact CE1-O 3.44Å; F275-L290 HydrophobicContact CE1-CD2 3.68Å; F275-L290 HydrophobicContact CZ-CD2 4.16Å; I284-L290 HydrophobicContact CD1-CD2 4.42Å; I284-L290 HydrophobicContact CG2-CD1 3.42Å; I284-L290 VanDerWaalsContact CG2-CD1 3.42Å; I284-L290 HydrophobicContact CG2-CD2 3.57Å; I284-L290 HydrophobicContact CG2-CG 4.09Å; S285-L290 WeakPolarHBondContact O-CD1 3.4Å; T287-L290 HydrophobicContact CG2-CD1 4.22Å; T287-L290 WeakPolarHBondContact O-CB 3.02Å; T287-L290 PolarHBondContact O-N 3.23Å; T287-L290 WeakPolarHBondContact OG1-CD1 3.49Å; T287-L290 PolarHBondContact OG1-N 3.43Å; L290-T293 PolarHBondContact O-N 3.01Å; L290-F294 WeakPolarHBondContact O-CB 3.44Å; L290-F294 PolarHBondContact O-N 2.8Å
291	R	70.7	Confident	74.5	Confident	48 Å²	48	50.1 Å²	50.1	18%	0.181	30%	0.304	C	S	.	.	H	α-helix	trans	-64.9	-49.7	175.1	177.8	-176.5	-72.7	150	-6.8	112.8	S21 F22 Q24 T287 P288 I289 T293 F294 A295	S21-R291 PolarHBondContact O-NE 3.34Å; S21-R291 PolarHBondContact O-NH2 3.47Å; F22-R291 HydrophobicContact CD1-CB 3.66Å; F22-R291 HydrophobicContact CD1-CG 3.9Å; F22-R291 HydrophobicContact CE1-CB 3.95Å; Q24-R291 PolarHBondContact O-NH2 2.73Å; T287-R291 PolarHBondContact O-N 3.05Å; T287-R291 VanDerWaalsContact O-N 3.08Å; P288-R291 PolarHBondContact O-N 3.25Å; I289-R291 VanDerWaalsContact C-N 3.28Å; I289-R291 PolarHBondContact O-N 3.08Å; R291-T293 VanDerWaalsContact C-N 3.25Å; R291-T293 PolarHBondContact O-N 3.05Å; R291-F294 PolarHBondContact O-N 3.32Å; R291-A295 PolarHBondContact O-N 3.21Å
292	S	72.4	Confident	75.4	Confident	28 Å²	28	47 Å²	47	20%	0.196	28%	0.282	C	S	.	.	H	α-helix	trans	-63.3	-35.1	175.2	-60.6	0	0	0	0	111.9	S43 P288 I289 F296	S43-S292 PolarHBondContact OG-OG 2.69Å; P288-S292 PolarHBondContact O-N 3.42Å; P288-S292 VanDerWaalsContact O-N 3.1Å; P288-S292 PolarHBondContact O-OG 3.1Å; I289-S292 PolarHBondContact O-N 3.27Å; S292-F296 WeakPolarHBondContact O-CB 2.9Å; S292-F296 PolarHBondContact O-N 2.9Å
293	T	80.6	Confident	76.6	Confident	54 Å²	54	45.7 Å²	45.7	33%	0.331	27%	0.266	S	S	.	.	H	α-helix	trans	-66.6	-45.3	176.8	-54	0	0	0	0	111.6	F275 I289 L290 R291 A295 F296 V297	F275-T293 HydrophobicContact CE2-CG2 3.77Å; F275-T293 HydrophobicContact CZ-CG2 3.47Å; F275-T293 VanDerWaalsContact CZ-CG2 3.47Å; I289-T293 WeakPolarHBondContact O-CB 3.35Å; I289-T293 PolarHBondContact O-N 3.38Å; I289-T293 PolarHBondContact O-OG1 3.05Å; L290-T293 PolarHBondContact O-N 3.01Å; R291-T293 VanDerWaalsContact C-N 3.25Å; R291-T293 PolarHBondContact O-N 3.05Å; T293-A295 PolarHBondContact O-N 2.91Å; T293-F296 PolarHBondContact O-N 3.46Å; T293-V297 WeakPolarHBondContact O-CB 3.47Å; T293-V297 WeakPolarHBondContact O-CG2 3.48Å; T293-V297 PolarHBondContact O-N 2.8Å
294	F	80.8	Confident	78.1	Confident	14 Å²	14	42.1 Å²	42.1	6%	0.061	24%	0.241	C	C	.	.	H	α-helix	trans	-61.5	-44.2	176.7	-179.3	-106.2	0	0	0	111.6	Y19 F22 F272 F275 L290 R291 F296 V297 V298	Y19-F294 HydrophobicContact CD2-CZ 4.47Å; F22-F294 HydrophobicContact CB-CD1 3.65Å; F22-F294 HydrophobicContact CB-CE1 4.04Å; F22-F294 HydrophobicContact CD1-CB 4Å; F22-F294 HydrophobicContact CD1-CD1 4.24Å; F22-F294 HydrophobicContact CD1-CG 4.36Å; F22-F294 HydrophobicContact CD2-CB 4.19Å; F22-F294 AromaticContact CD2-CD1 3.59Å; F22-F294 HydrophobicContact CD2-CD1 3.59Å; F22-F294 HydrophobicContact CD2-CD2 4.34Å; F22-F294 AromaticContact CD2-CE1 3.97Å; F22-F294 HydrophobicContact CD2-CE1 3.97Å; F22-F294 AromaticContact CD2-CG 3.77Å; F22-F294 HydrophobicContact CD2-CG 3.77Å; F22-F294 HydrophobicContact CE1-CB 3.93Å; F22-F294 HydrophobicContact CE2-CB 4.12Å; F22-F294 HydrophobicContact CE2-CD1 4.25Å; F22-F294 HydrophobicContact CE2-CD2 4.28Å; F22-F294 AromaticContact CE2-CG 3.95Å; F22-F294 HydrophobicContact CE2-CG 3.95Å; F22-F294 HydrophobicContact CG-CB 4.14Å; F22-F294 AromaticContact CG-CD1 3.57Å; F22-F294 HydrophobicContact CG-CD1 3.57Å; F22-F294 HydrophobicContact CG-CE1 4.21Å; F22-F294 AromaticContact CG-CG 3.99Å; F22-F294 HydrophobicContact CG-CG 3.99Å; F22-F294 HydrophobicContact CZ-CB 3.98Å; F22-F294 HydrophobicContact CZ-CG 4.33Å; F272-F294 HydrophobicContact CE2-CZ 4.45Å; F275-F294 HydrophobicContact CB-CD2 4.02Å; F275-F294 HydrophobicContact CB-CE2 4.34Å; F275-F294 HydrophobicContact CD1-CB 4.48Å; F275-F294 HydrophobicContact CD1-CD2 4.12Å; F275-F294 HydrophobicContact CG-CD2 4.15Å; L290-F294 WeakPolarHBondContact O-CB 3.44Å; L290-F294 PolarHBondContact O-N 2.8Å; R291-F294 PolarHBondContact O-N 3.32Å; F294-F296 VanDerWaalsContact C-N 3.33Å; F294-F296 PolarHBondContact O-N 3.49Å; F294-V297 WeakPolarHBondContact O-CB 3.29Å; F294-V297 PolarHBondContact O-N 2.69Å; F294-V297 VanDerWaalsContact O-N 3.13Å; F294-V298 HydrophobicContact CD1-CG2 4.34Å; F294-V298 HydrophobicContact CE1-CG2 3.98Å; F294-V298 HydrophobicContact CE2-CG2 4.45Å; F294-V298 HydrophobicContact CZ-CG2 4.05Å; F294-V298 WeakPolarHBondContact O-CG2 3.3Å; F294-V298 PolarHBondContact O-N 2.98Å
295	A	77.9	Confident	79.4	Confident	18 Å²	18	40 Å²	40	15%	0.149	23%	0.231	C	C	.	.	H	α-helix	trans	-61	-40.9	176.4	0	0	0	0	0	112.6	I47 R291 T293 V298 V299	I47-A295 HydrophobicContact CD1-CB 3.42Å; I47-A295 VanDerWaalsContact CD1-CB 3.42Å; I47-A295 HydrophobicContact CG1-CB 4.09Å; I47-A295 HydrophobicContact CG2-CB 4.33Å; R291-A295 PolarHBondContact O-N 3.21Å; T293-A295 PolarHBondContact O-N 2.91Å; A295-V298 PolarHBondContact O-N 3.25Å; A295-V299 WeakPolarHBondContact O-CG2 3.34Å; A295-V299 PolarHBondContact O-N 3.42Å
296	F	83	Confident	80.7	Confident	107 Å²	107	35.7 Å²	35.7	47%	0.469	20%	0.2	S	C	.	.	H	α-helix	trans	-63	-41.1	173.5	178.3	-96.7	0	0	0	112.3	M50 S292 T293 F294 V298 V299 L300	M50-F296 HydrophobicContact CE-CD2 4.42Å; M50-F296 HydrophobicContact CE-CE2 4.27Å; M50-F296 HydrophobicContact SD-CD2 4.5Å; S292-F296 WeakPolarHBondContact O-CB 2.9Å; S292-F296 PolarHBondContact O-N 2.9Å; T293-F296 PolarHBondContact O-N 3.46Å; F294-F296 VanDerWaalsContact C-N 3.33Å; F294-F296 PolarHBondContact O-N 3.49Å; F296-V298 VanDerWaalsContact C-N 3.3Å; F296-V298 PolarHBondContact O-N 3.19Å; F296-V299 WeakPolarHBondContact O-CB 3.38Å; F296-V299 PolarHBondContact O-N 3.27Å; F296-L300 WeakPolarHBondContact O-CB 3.28Å; F296-L300 PolarHBondContact O-N 3.38Å
297	V	87.4	Confident	81.7	Confident	8 Å²	8	32.7 Å²	32.7	5%	0.048	18%	0.184	C	C	.	.	H	α-helix	trans	-61.6	-38	175.8	162.4	0	0	0	0	111.7	P271 F272 F275 T293 F294 L300 G301	P271-V297 VanDerWaalsContact C-CG1 3.49Å; P271-V297 HydrophobicContact CB-CB 4.47Å; P271-V297 HydrophobicContact CB-CG1 3.88Å; P271-V297 HydrophobicContact CB-CG2 3.82Å; F272-V297 HydrophobicContact CB-CG1 3.76Å; F275-V297 HydrophobicContact CD2-CB 4.46Å; F275-V297 HydrophobicContact CD2-CG1 4.34Å; F275-V297 HydrophobicContact CD2-CG2 3.9Å; F275-V297 HydrophobicContact CE2-CG2 3.85Å; T293-V297 WeakPolarHBondContact O-CB 3.47Å; T293-V297 WeakPolarHBondContact O-CG2 3.48Å; T293-V297 PolarHBondContact O-N 2.8Å; F294-V297 WeakPolarHBondContact O-CB 3.29Å; F294-V297 PolarHBondContact O-N 2.69Å; F294-V297 VanDerWaalsContact O-N 3.13Å; V297-L300 WeakPolarHBondContact O-CB 3.42Å; V297-L300 PolarHBondContact O-N 2.89Å; V297-G301 PolarHBondContact O-N 3.19Å; V297-G301 VanDerWaalsContact O-N 3.08Å
298	V	85.2	Confident	82.3	Confident	19 Å²	19	30 Å²	30	12%	0.115	17%	0.167	C	C	.	.	H	α-helix	trans	-64.7	-46.5	173.4	173.7	0	0	0	0	111.2	Y51 F272 F294 A295 F296 L300 G301 Y302	Y51-V298 WeakPolarHBondContact OH-CG1 3.38Å; F272-V298 HydrophobicContact CD2-CG2 4.21Å; F272-V298 HydrophobicContact CE2-CG2 4.26Å; F294-V298 HydrophobicContact CD1-CG2 4.34Å; F294-V298 HydrophobicContact CE1-CG2 3.98Å; F294-V298 HydrophobicContact CE2-CG2 4.45Å; F294-V298 HydrophobicContact CZ-CG2 4.05Å; F294-V298 WeakPolarHBondContact O-CG2 3.3Å; F294-V298 PolarHBondContact O-N 2.98Å; A295-V298 PolarHBondContact O-N 3.25Å; F296-V298 VanDerWaalsContact C-N 3.3Å; F296-V298 PolarHBondContact O-N 3.19Å; V298-L300 PolarHBondContact O-N 2.7Å; V298-G301 WeakPolarHBondContact O-CA 3.45Å; V298-G301 PolarHBondContact O-N 2.98Å; V298-G301 VanDerWaalsContact O-N 3.08Å; V298-Y302 HydrophobicContact CG1-CD2 4.36Å; V298-Y302 HydrophobicContact CG1-CE1 4.32Å; V298-Y302 HydrophobicContact CG1-CE2 3.54Å; V298-Y302 WeakPolarHBondContact CG1-OH 3.44Å; V298-Y302 PolarHBondContact O-N 3.33Å
299	V	87.8	Confident	83	Confident	10 Å²	10	28.5 Å²	28.5	6%	0.061	16%	0.157	C	C	.	.	H	α-helix	trans	-57.1	-40.5	174.1	173	0	0	0	0	111.4	I47 M50 Y51 V54 A295 F296 G301 Y302 A303	I47-V299 HydrophobicContact CG2-CG2 4.28Å; M50-V299 HydrophobicContact CB-CG1 3.99Å; M50-V299 HydrophobicContact CB-CG2 4.26Å; M50-V299 HydrophobicContact SD-CG1 4.22Å; Y51-V299 HydrophobicContact CD2-CG2 3.64Å; Y51-V299 HydrophobicContact CE2-CG2 3.34Å; V54-V299 HydrophobicContact CG2-CG1 4.24Å; A295-V299 WeakPolarHBondContact O-CG2 3.34Å; A295-V299 PolarHBondContact O-N 3.42Å; F296-V299 WeakPolarHBondContact O-CB 3.38Å; F296-V299 PolarHBondContact O-N 3.27Å; V299-G301 VanDerWaalsContact C-N 3.29Å; V299-G301 PolarHBondContact O-N 3.41Å; V299-Y302 WeakPolarHBondContact O-CB 3.47Å; V299-Y302 PolarHBondContact O-N 3.44Å; V299-Y302 VanDerWaalsContact O-N 3.11Å; V299-A303 PolarHBondContact O-N 2.9Å
300	L	89.2	Confident	83.2	Confident	27 Å²	27	27 Å²	27	14%	0.141	15%	0.149	C	C	.	.	H	α-helix	trans	-64	-35.9	178.6	-177.8	63.3	0	0	0	111.9	F267 C268 P271 F296 V297 V298 Y302 A303	F267-L300 HydrophobicContact CD1-CD1 4.27Å; F267-L300 HydrophobicContact CE1-CD1 3.85Å; F267-L300 HydrophobicContact CE1-CD2 4.28Å; C268-L300 WeakPolarHBondContact CB-O 3.36Å; C268-L300 PolarHBondContact SG-O 3.35Å; C268-L300 VanDerWaalsContact SG-O 3.33Å; P271-L300 HydrophobicContact CG-CD2 4.15Å; F296-L300 WeakPolarHBondContact O-CB 3.28Å; F296-L300 PolarHBondContact O-N 3.38Å; V297-L300 WeakPolarHBondContact O-CB 3.42Å; V297-L300 PolarHBondContact O-N 2.89Å; V298-L300 PolarHBondContact O-N 2.7Å; L300-Y302 VanDerWaalsContact C-N 3.34Å; L300-A303 WeakPolarHBondContact O-CB 3.2Å; L300-A303 PolarHBondContact O-N 2.89Å
301	G	87.8	Confident	83.1	Confident	4 Å²	4	26.2 Å²	26.2	4%	0.041	15%	0.145	C	C	.	.	H	α-helix	trans	-58.3	-44.6	169.7	0	0	0	0	0	112.1	V297 V298 V299 A303 N304	V297-G301 PolarHBondContact O-N 3.19Å; V297-G301 VanDerWaalsContact O-N 3.08Å; V298-G301 WeakPolarHBondContact O-CA 3.45Å; V298-G301 PolarHBondContact O-N 2.98Å; V298-G301 VanDerWaalsContact O-N 3.08Å; V299-G301 VanDerWaalsContact C-N 3.29Å; V299-G301 PolarHBondContact O-N 3.41Å; G301-A303 PolarHBondContact O-N 3.5Å; G301-N304 WeakPolarHBondContact O-CB 3.48Å; G301-N304 PolarHBondContact O-N 2.9Å
302	Y	89.3	Confident	83.1	Confident	23 Å²	23	24 Å²	24	9%	0.09	14%	0.137	C	C	.	.	H	α-helix	trans	-68.9	-32.2	177.5	-54.1	-30.6	0	0	0	113.4	Y51 F93 L97 D123 V298 V299 L300 N304 S305	Y51-Y302 HydrophobicContact CD1-CD2 4.5Å; Y51-Y302 HydrophobicContact CD1-CE2 4.11Å; Y51-Y302 HydrophobicContact CE1-CD2 4.17Å; Y51-Y302 AromaticContact CE1-CE2 3.41Å; Y51-Y302 HydrophobicContact CE1-CE2 3.41Å; Y51-Y302 VanDerWaalsContact CE1-CE2 3.41Å; Y51-Y302 HydrophobicContact CE2-CE2 4.22Å; Y51-Y302 AromaticContact CZ-CE2 3.49Å; Y51-Y302 VanDerWaalsContact CZ-CE2 3.49Å; F93-Y302 HydrophobicContact CE1-CD1 4.01Å; F93-Y302 HydrophobicContact CE1-CG 4.45Å; F93-Y302 HydrophobicContact CE2-CD1 4.15Å; F93-Y302 HydrophobicContact CE2-CE1 4.11Å; F93-Y302 AromaticContact CZ-CD1 3.25Å; F93-Y302 HydrophobicContact CZ-CD1 3.25Å; F93-Y302 AromaticContact CZ-CE1 3.64Å; F93-Y302 HydrophobicContact CZ-CE1 3.64Å; F93-Y302 AromaticContact CZ-CG 3.9Å; F93-Y302 HydrophobicContact CZ-CG 3.9Å; L97-Y302 HydrophobicContact CD2-CD1 4.26Å; L97-Y302 HydrophobicContact CD2-CD2 3.68Å; L97-Y302 HydrophobicContact CD2-CE1 4.18Å; L97-Y302 HydrophobicContact CD2-CE2 3.66Å; L97-Y302 HydrophobicContact CD2-CG 3.97Å; D123-Y302 WeakPolarHBondContact OD1-CE1 3.3Å; V298-Y302 HydrophobicContact CG1-CD2 4.36Å; V298-Y302 HydrophobicContact CG1-CE1 4.32Å; V298-Y302 HydrophobicContact CG1-CE2 3.54Å; V298-Y302 WeakPolarHBondContact CG1-OH 3.44Å; V298-Y302 PolarHBondContact O-N 3.33Å; V299-Y302 WeakPolarHBondContact O-CB 3.47Å; V299-Y302 PolarHBondContact O-N 3.44Å; V299-Y302 VanDerWaalsContact O-N 3.11Å; L300-Y302 VanDerWaalsContact C-N 3.34Å; Y302-N304 PolarHBondContact O-N 3.43Å; Y302-N304 VanDerWaalsContact O-N 3.16Å; Y302-S305 PolarHBondContact O-N 3.18Å
303	A	88.9	Confident	82.9	Confident	29 Å²	29	23.7 Å²	23.7	24%	0.24	14%	0.136	C	C	.	.	H	α-helix	trans	-61.5	-20.5	175.2	0	0	0	0	0	113.1	V299 L300 G301 S305 C306 A307	V299-A303 PolarHBondContact O-N 2.9Å; L300-A303 WeakPolarHBondContact O-CB 3.2Å; L300-A303 PolarHBondContact O-N 2.89Å; G301-A303 PolarHBondContact O-N 3.5Å; A303-S305 VanDerWaalsContact C-N 3.29Å; A303-S305 PolarHBondContact O-N 3.47Å; A303-C306 WeakPolarHBondContact O-CB 3.47Å; A303-C306 PolarHBondContact O-N 3.13Å; A303-C306 VanDerWaalsContact O-N 3.08Å; A303-A307 PolarHBondContact O-N 3.2Å; A303-A307 VanDerWaalsContact O-N 3.11Å
304	N	89.7	Confident	82.1	Confident	3 Å²	3	28.8 Å²	28.8	2%	0.016	15%	0.154	C	C	.	.	H	α-helix	trans	-53.2	-46.3	172.6	178.6	63.9	0	0	0	112	F265 C268 G301 Y302 C306 A307	F265-N304 WeakPolarHBondContact CA-OD1 3.42Å; C268-N304 HydrophobicContact CB-CB 3.77Å; G301-N304 WeakPolarHBondContact O-CB 3.48Å; G301-N304 PolarHBondContact O-N 2.9Å; Y302-N304 PolarHBondContact O-N 3.43Å; Y302-N304 VanDerWaalsContact O-N 3.16Å; N304-C306 VanDerWaalsContact C-N 3.26Å; N304-C306 PolarHBondContact O-N 3.3Å; N304-A307 WeakPolarHBondContact O-CB 3.34Å; N304-A307 PolarHBondContact O-N 3.41Å; N304-A307 VanDerWaalsContact O-N 3.16Å
305	S	88.4	Confident	81.2	Confident	1 Å²	1	29 Å²	29	1%	0.007	16%	0.156	C	C	.	.	H	α-helix	trans	-68.1	-24.6	179.8	-70.5	0	0	0	0	112.9	N62 D90 N126 Y302 A303	N62-S305 PolarHBondContact ND2-O 2.96Å; D90-S305 WeakPolarHBondContact OD1-CB 3.48Å; D90-S305 PolarHBondContact OD1-OG 3Å; N126-S305 PolarHBondContact ND2-OG 3.28Å; Y302-S305 PolarHBondContact O-N 3.18Å; A303-S305 VanDerWaalsContact C-N 3.29Å; A303-S305 PolarHBondContact O-N 3.47Å
306	C	88	Confident	80.6	Confident	12 Å²	12	29.3 Å²	29.3	8%	0.081	16%	0.157	C	C	.	.	H	α-helix	trans	-77.3	-28.3	173.1	-64.7	0	0	0	0	112.9	V54 V57 G58 A303 N304 N308	V54-C306 PolarHBondContact O-SG 2.93Å; V57-C306 HydrophobicContact CG1-CB 4.13Å; G58-C306 VanDerWaalsContact CA-SG 3.57Å; G58-C306 PolarHBondContact N-SG 3.24Å; A303-C306 WeakPolarHBondContact O-CB 3.47Å; A303-C306 PolarHBondContact O-N 3.13Å; A303-C306 VanDerWaalsContact O-N 3.08Å; N304-C306 VanDerWaalsContact C-N 3.26Å; N304-C306 PolarHBondContact O-N 3.3Å; C306-N308 VanDerWaalsContact C-N 3.31Å; C306-N308 PolarHBondContact O-N 2.99Å
307	A	84.9	Confident	79.7	Confident	18 Å²	18	28.9 Å²	28.9	15%	0.149	16%	0.156	C	C	.	.	H	α-helix	trans	-70.1	-29.2	-179.8	0	0	0	0	0	112.4	V264 A303 N304 I310 L311	V264-A307 HydrophobicContact CG1-CB 3.58Å; A303-A307 PolarHBondContact O-N 3.2Å; A303-A307 VanDerWaalsContact O-N 3.11Å; N304-A307 WeakPolarHBondContact O-CB 3.34Å; N304-A307 PolarHBondContact O-N 3.41Å; N304-A307 VanDerWaalsContact O-N 3.16Å; A307-I310 WeakPolarHBondContact O-CB 3.15Å; A307-I310 PolarHBondContact O-N 2.88Å; A307-L311 HydrophobicContact CB-CD1 4.38Å; A307-L311 WeakPolarHBondContact O-CB 3.24Å; A307-L311 WeakPolarHBondContact O-CG 3.41Å; A307-L311 PolarHBondContact O-N 3.31Å
308	N	83.2	Confident	78.5	Confident	3 Å²	3	33 Å²	33	2%	0.016	18%	0.178	C	C	.	.	H	α-helix	trans	-55.2	-56	-175.9	-68	-31	0	0	0	112.9	L86 D90 C306 I310 L311 Y312	L86-N308 HydrophobicContact CD2-CB 4.38Å; D90-N308 PolarHBondContact OD2-ND2 3.35Å; C306-N308 VanDerWaalsContact C-N 3.31Å; C306-N308 PolarHBondContact O-N 2.99Å; N308-I310 VanDerWaalsContact C-N 3.34Å; N308-I310 PolarHBondContact O-N 3.41Å; N308-L311 PolarHBondContact O-N 3.11Å; N308-Y312 HydrophobicContact CB-CE2 4.04Å; N308-Y312 WeakPolarHBondContact O-CD2 3.47Å; N308-Y312 WeakPolarHBondContact O-CE2 3.18Å; N308-Y312 VanDerWaalsContact O-CG 3.27Å; N308-Y312 PolarHBondContact O-N 2.94Å
309	P	80.8	Confident	77.5	Confident	15 Å²	15	32.5 Å²	32.5	10%	0.097	17%	0.174	C	C	.	.	H	α-helix	trans	-57.2	-41.2	175.2	-26.6	33.9	0	0	0	114.5	N62 V65 Y312 A313	N62-P309 HydrophobicContact CB-CG 4.39Å; N62-P309 WeakPolarHBondContact OD1-CD 3.35Å; N62-P309 WeakPolarHBondContact OD1-CG 3.14Å; V65-P309 HydrophobicContact CG2-CB 3.94Å; V65-P309 HydrophobicContact CG2-CG 4.17Å; P309-Y312 PolarHBondContact O-N 2.92Å; P309-A313 WeakPolarHBondContact O-CB 3.3Å; P309-A313 PolarHBondContact O-N 3.41Å
310	I	75.8	Confident	76.4	Confident	87 Å²	87	36.7 Å²	36.7	45%	0.446	19%	0.192	S	C	.	.	H	α-helix	trans	-60.5	-50.6	179.5	-64.6	174.6	0	0	0	109.1	A307 N308 Y312 A313 F314	A307-I310 WeakPolarHBondContact O-CB 3.15Å; A307-I310 PolarHBondContact O-N 2.88Å; N308-I310 VanDerWaalsContact C-N 3.34Å; N308-I310 PolarHBondContact O-N 3.41Å; I310-Y312 VanDerWaalsContact C-N 3.31Å; I310-Y312 PolarHBondContact O-N 2.93Å; I310-A313 PolarHBondContact O-N 3.32Å; I310-F314 HydrophobicContact CG2-CD2 3.73Å; I310-F314 HydrophobicContact CG2-CE2 3.8Å; I310-F314 WeakPolarHBondContact O-CD2 3.12Å; I310-F314 PolarHBondContact O-N 2.91Å
311	L	73.3	Confident	75.3	Confident	22 Å²	22	41.6 Å²	41.6	12%	0.115	21%	0.212	C	C	.	.	H	α-helix	trans	-59.7	-42	178.7	-67.8	175.3	0	0	0	111.4	I260 V261 V264 A307 N308 L315	I260-L311 HydrophobicContact CG2-CD1 4.5Å; I260-L311 HydrophobicContact CG2-CD2 3.46Å; I260-L311 VanDerWaalsContact CG2-CD2 3.46Å; V261-L311 HydrophobicContact CB-CD1 4.12Å; V261-L311 HydrophobicContact CG1-CD1 4.46Å; V261-L311 HydrophobicContact CG2-CB 4.25Å; V261-L311 HydrophobicContact CG2-CD1 3.6Å; V264-L311 HydrophobicContact CB-CD1 4.41Å; V264-L311 HydrophobicContact CG2-CD1 4.14Å; A307-L311 HydrophobicContact CB-CD1 4.38Å; A307-L311 WeakPolarHBondContact O-CB 3.24Å; A307-L311 WeakPolarHBondContact O-CG 3.41Å; A307-L311 PolarHBondContact O-N 3.31Å; N308-L311 PolarHBondContact O-N 3.11Å; L311-L315 HydrophobicContact CB-CD1 4.16Å; L311-L315 HydrophobicContact CD2-CD1 3.91Å; L311-L315 WeakPolarHBondContact O-CB 3.38Å; L311-L315 WeakPolarHBondContact O-CD1 3.26Å; L311-L315 VanDerWaalsContact O-CG 3.28Å; L311-L315 WeakPolarHBondContact O-CG 3.33Å; L311-L315 PolarHBondContact O-N 3.5Å
312	Y	71.3	Confident	74.1	Confident	3 Å²	3	42 Å²	42	1%	0.012	21%	0.214	C	C	.	.	H	α-helix	trans	-67.9	-40.8	177.3	-57.1	-37.1	0	0	0	113.3	V65 I83 L86 M257 N308 P309 I310 F314 S316	V65-Y312 HydrophobicContact CG2-CD2 4.31Å; I83-Y312 HydrophobicContact CB-CE2 4.42Å; I83-Y312 HydrophobicContact CD1-CD1 4.25Å; I83-Y312 HydrophobicContact CD1-CE1 4.14Å; I83-Y312 HydrophobicContact CG1-CE1 4.01Å; I83-Y312 HydrophobicContact CG1-CE2 4.33Å; I83-Y312 HydrophobicContact CG2-CD2 3.76Å; I83-Y312 HydrophobicContact CG2-CE2 3.5Å; I83-Y312 HydrophobicContact CG2-CG 4.4Å; L86-Y312 VanDerWaalsContact CD2-OH 3.25Å; L86-Y312 WeakPolarHBondContact CD2-OH 3.38Å; M257-Y312 HydrophobicContact CE-CD1 3.89Å; M257-Y312 HydrophobicContact CE-CE1 3.82Å; M257-Y312 HydrophobicContact SD-CD1 4.16Å; N308-Y312 HydrophobicContact CB-CE2 4.04Å; N308-Y312 WeakPolarHBondContact O-CD2 3.47Å; N308-Y312 WeakPolarHBondContact O-CE2 3.18Å; N308-Y312 VanDerWaalsContact O-CG 3.27Å; N308-Y312 PolarHBondContact O-N 2.94Å; P309-Y312 PolarHBondContact O-N 2.92Å; I310-Y312 VanDerWaalsContact C-N 3.31Å; I310-Y312 PolarHBondContact O-N 2.93Å; Y312-F314 VanDerWaalsContact C-N 3.34Å; Y312-F314 PolarHBondContact O-N 3.42Å; Y312-S316 WeakPolarHBondContact O-CB 3.35Å; Y312-S316 PolarHBondContact O-N 3.48Å
313	A	67.5	Low	73.1	Confident	21 Å²	21	44.4 Å²	44.4	17%	0.174	23%	0.225	C	C	.	.	H	α-helix	trans	-62.8	-39.3	178.6	0	0	0	0	0	112.3	P309 I310	P309-A313 WeakPolarHBondContact O-CB 3.3Å; P309-A313 PolarHBondContact O-N 3.41Å; I310-A313 PolarHBondContact O-N 3.32Å
314	F	63.8	Low	72.1	Confident	160 Å²	160	47.5 Å²	47.5	70%	0.702	24%	0.235	S	C	*	.	H	α-helix	trans	-85.5	-31.4	179.9	-72.1	-69.5	0	0	0	113.8	I310 Y312	I310-F314 HydrophobicContact CG2-CD2 3.73Å; I310-F314 HydrophobicContact CG2-CE2 3.8Å; I310-F314 WeakPolarHBondContact O-CD2 3.12Å; I310-F314 PolarHBondContact O-N 2.91Å; Y312-F314 VanDerWaalsContact C-N 3.34Å; Y312-F314 PolarHBondContact O-N 3.42Å
315	L	61.3	Low	70.9	Confident	19 Å²	19	51.8 Å²	51.8	10%	0.099	26%	0.258	C	S	.	.	H	α-helix	trans	-103	-20.7	-169.5	-59.5	163.6	0	0	0	113.8	K253 M257 I260 L311	K253-L315 WeakPolarHBondContact CE-O 3.37Å; K253-L315 PolarHBondContact NZ-O 2.82Å; M257-L315 HydrophobicContact CB-CB 4.02Å; M257-L315 HydrophobicContact CB-CD1 4.29Å; M257-L315 HydrophobicContact CG-CB 3.62Å; M257-L315 HydrophobicContact CG-CD1 3.85Å; M257-L315 HydrophobicContact CG-CG 4.35Å; M257-L315 HydrophobicContact SD-CB 4.08Å; I260-L315 HydrophobicContact CB-CD1 4.31Å; I260-L315 HydrophobicContact CD1-CD1 3.82Å; I260-L315 HydrophobicContact CD1-CD2 3.88Å; I260-L315 HydrophobicContact CG2-CD1 4.34Å; L311-L315 HydrophobicContact CB-CD1 4.16Å; L311-L315 HydrophobicContact CD2-CD1 3.91Å; L311-L315 WeakPolarHBondContact O-CB 3.38Å; L311-L315 WeakPolarHBondContact O-CD1 3.26Å; L311-L315 VanDerWaalsContact O-CG 3.28Å; L311-L315 WeakPolarHBondContact O-CG 3.33Å; L311-L315 PolarHBondContact O-N 3.5Å
316	S	66	Low	69.9	Low	25 Å²	25	53.1 Å²	53.1	18%	0.175	27%	0.266	C	S	.	.			trans	-103.5	118.5	176.9	-177	0	0	0	0	112.1	Y312 N318 F319 K320	Y312-S316 WeakPolarHBondContact O-CB 3.35Å; Y312-S316 PolarHBondContact O-N 3.48Å; S316-N318 PolarHBondContact O-N 3.05Å; S316-F319 PolarHBondContact O-N 2.87Å; S316-F319 WeakPolarHBondContact OG-CD2 3.39Å; S316-K320 WeakPolarHBondContact O-CB 3.16Å; S316-K320 PolarHBondContact O-N 2.95Å
317	E	63.5	Low	68.9	Low	97 Å²	97	58.3 Å²	58.3	45%	0.453	29%	0.292	S	S	.	.	H	α-helix	trans	-60.6	-34.8	177.4	-68.1	-54.9	144.7	0	0	111.9	K253 K320 K321	K253-E317 VanDerWaalsContact NZ-CD 3.31Å; K253-E317 VanDerWaalsContact NZ-CG 3.28Å; K253-E317 IonicContact NZ-OE1 2.63Å; K253-E317 PolarHBondContact NZ-OE1 3.11Å; E317-K320 PolarHBondContact O-N 3.18Å; E317-K321 WeakPolarHBondContact O-CB 3.32Å; E317-K321 WeakPolarHBondContact O-CG 3.35Å; E317-K321 PolarHBondContact O-N 3.15Å
318	N	62.4	Low	67.9	Low	95 Å²	95	61.9 Å²	61.9	51%	0.508	32%	0.315	S	S	.	.	H	α-helix	trans	-70	-38.3	-179.1	-65.4	-14.8	0	0	0	110.9	M75 S316 S322	M75-N318 HydrophobicContact CE-CB 4.28Å; M75-N318 HydrophobicContact SD-CB 3.93Å; S316-N318 PolarHBondContact O-N 3.05Å; N318-S322 VanDerWaalsContact O-CB 3.3Å; N318-S322 WeakPolarHBondContact O-CB 3.29Å; N318-S322 PolarHBondContact O-N 3.43Å; N318-S322 VanDerWaalsContact O-N 3.13Å; N318-S322 PolarHBondContact O-OG 2.93Å
319	F	63.9	Low	66.5	Low	9 Å²	9	67.8 Å²	67.8	4%	0.039	35%	0.346	C	S	.	.	H	α-helix	trans	-71.5	-44.6	173	-81.3	-89.6	0	0	0	111	V65 V68 I69 M75 I83 S316 K321 S322 F323	V65-F319 HydrophobicContact CG1-CE1 4.11Å; V65-F319 HydrophobicContact CG1-CZ 4.49Å; V68-F319 HydrophobicContact CG1-CD1 4.08Å; V68-F319 HydrophobicContact CG1-CE1 4.17Å; I69-F319 HydrophobicContact CD1-CE1 4.18Å; I69-F319 HydrophobicContact CD1-CZ 3.73Å; I69-F319 HydrophobicContact CG1-CE1 3.82Å; I69-F319 HydrophobicContact CG1-CZ 3.57Å; M75-F319 HydrophobicContact CE-CD2 3.73Å; M75-F319 HydrophobicContact CE-CE1 4.19Å; M75-F319 HydrophobicContact CE-CE2 3.36Å; M75-F319 HydrophobicContact CE-CG 4.3Å; M75-F319 HydrophobicContact CE-CZ 3.62Å; I83-F319 HydrophobicContact CD1-CE2 3.99Å; I83-F319 HydrophobicContact CD1-CZ 4.43Å; I83-F319 HydrophobicContact CG2-CZ 4.01Å; S316-F319 PolarHBondContact O-N 2.87Å; S316-F319 WeakPolarHBondContact OG-CD2 3.39Å; F319-K321 PolarHBondContact O-N 2.87Å; F319-S322 PolarHBondContact O-N 3.25Å; F319-S322 VanDerWaalsContact O-N 3.16Å; F319-F323 WeakPolarHBondContact O-CB 3.29Å; F319-F323 PolarHBondContact O-N 3.34Å
320	K	65.7	Low	64.9	Low	97 Å²	97	75.8 Å²	75.8	42%	0.422	38%	0.379	S	S	.	.	H	α-helix	trans	-54.7	-49.6	176.9	-172	177.7	178.6	-178.8	0	112	S316 E317 F323 Q324	S316-K320 WeakPolarHBondContact O-CB 3.16Å; S316-K320 PolarHBondContact O-N 2.95Å; E317-K320 PolarHBondContact O-N 3.18Å; K320-F323 PolarHBondContact O-N 3.48Å; K320-Q324 WeakPolarHBondContact O-CB 3.28Å; K320-Q324 WeakPolarHBondContact O-CG 3.4Å; K320-Q324 PolarHBondContact O-N 2.94Å
321	K	64.9	Low	63	Low	130 Å²	130	81.4 Å²	81.4	57%	0.565	40%	0.4	S	S	*	.	H	α-helix	trans	-63.7	-41.2	177.2	-74	-176.7	178.4	-171.1	0	112.6	E317 F319 N325	E317-K321 WeakPolarHBondContact O-CB 3.32Å; E317-K321 WeakPolarHBondContact O-CG 3.35Å; E317-K321 PolarHBondContact O-N 3.15Å; F319-K321 PolarHBondContact O-N 2.87Å; K321-N325 WeakPolarHBondContact O-CB 3.32Å; K321-N325 PolarHBondContact O-N 2.75Å; K321-N325 PolarHBondContact O-ND2 3.4Å; K321-N325 PolarHBondContact O-OD1 2.75Å
322	S	64.1	Low	61.8	Low	13 Å²	13	86.8 Å²	86.8	9%	0.091	43%	0.434	C	S	.	.	H	α-helix	trans	-70.8	-38.6	179.6	-57	0	0	0	0	112.2	N318 F319 N325 V326	N318-S322 VanDerWaalsContact O-CB 3.3Å; N318-S322 WeakPolarHBondContact O-CB 3.29Å; N318-S322 PolarHBondContact O-N 3.43Å; N318-S322 VanDerWaalsContact O-N 3.13Å; N318-S322 PolarHBondContact O-OG 2.93Å; F319-S322 PolarHBondContact O-N 3.25Å; F319-S322 VanDerWaalsContact O-N 3.16Å; S322-N325 PolarHBondContact O-N 3.49Å; S322-V326 WeakPolarHBondContact O-CG2 3.43Å; S322-V326 PolarHBondContact O-N 3.31Å
323	F	66.9	Low	60.1	Low	74 Å²	74	89.7 Å²	89.7	33%	0.325	47%	0.465	S	S	.	.	H	α-helix	trans	-66.4	-42.2	176.1	-165.5	-93.2	0	0	0	111.1	L64 F319 K320 N325 V326 L327	L64-F323 HydrophobicContact CD2-CD2 3.76Å; L64-F323 HydrophobicContact CD2-CE2 3.16Å; L64-F323 HydrophobicContact CD2-CZ 3.94Å; L64-F323 HydrophobicContact CG-CD2 4.2Å; L64-F323 HydrophobicContact CG-CE2 3.99Å; F319-F323 WeakPolarHBondContact O-CB 3.29Å; F319-F323 PolarHBondContact O-N 3.34Å; K320-F323 PolarHBondContact O-N 3.48Å; F323-N325 VanDerWaalsContact C-N 3.34Å; F323-V326 PolarHBondContact O-N 2.99Å; F323-L327 HydrophobicContact CD1-CD1 3.48Å; F323-L327 VanDerWaalsContact CD1-CD1 3.48Å; F323-L327 HydrophobicContact CD1-CG 4.12Å; F323-L327 HydrophobicContact CE1-CD1 3.09Å; F323-L327 HydrophobicContact CE1-CG 4.01Å; F323-L327 HydrophobicContact CG-CD1 4.5Å; F323-L327 HydrophobicContact CZ-CD1 3.87Å; F323-L327 WeakPolarHBondContact O-CB 3.43Å; F323-L327 PolarHBondContact O-N 2.98Å
324	Q	67.8	Low	58.7	Low	94 Å²	94	91.8 Å²	91.8	44%	0.439	49%	0.488	S	S	.	.	H	α-helix	trans	-59.7	-43.8	169.5	-75.7	174.5	-26.9	0	0	111.2	K320 V326 C328	K320-Q324 WeakPolarHBondContact O-CB 3.28Å; K320-Q324 WeakPolarHBondContact O-CG 3.4Å; K320-Q324 PolarHBondContact O-N 2.94Å; Q324-V326 VanDerWaalsContact C-N 3.28Å; Q324-V326 PolarHBondContact O-N 3.47Å; Q324-C328 WeakPolarHBondContact O-CA 3.32Å; Q324-C328 WeakPolarHBondContact O-CB 3.45Å; Q324-C328 PolarHBondContact O-N 3.1Å; Q324-C328 PolarHBondContact O-SG 3.05Å
325	N	65.8	Low	57.7	Low	93 Å²	93	91 Å²	91	50%	0.497	49%	0.491	S	S	.	.	H	α-helix	trans	-65.3	-30.6	178.1	-70.6	-15.3	0	0	0	113.4	K321 S322 F323 L329	K321-N325 WeakPolarHBondContact O-CB 3.32Å; K321-N325 PolarHBondContact O-N 2.75Å; K321-N325 PolarHBondContact O-ND2 3.4Å; K321-N325 PolarHBondContact O-OD1 2.75Å; S322-N325 PolarHBondContact O-N 3.49Å; F323-N325 VanDerWaalsContact C-N 3.34Å; N325-L329 WeakPolarHBondContact O-CD2 3.5Å; N325-L329 VanDerWaalsContact O-CG 3.25Å; N325-L329 WeakPolarHBondContact O-CG 3.27Å
326	V	66.9	Low	56.8	Low	29 Å²	29	98 Å²	98	18%	0.176	53%	0.528	C	S	.	.	H	α-helix	trans	-81.1	-44	178	172.8	0	0	0	0	111.9	L64 Y67 V68 S322 F323 Q324 L329	L64-V326 HydrophobicContact CD1-CG1 4.34Å; Y67-V326 HydrophobicContact CE1-CG1 4.26Å; Y67-V326 HydrophobicContact CE1-CG2 4.06Å; V68-V326 HydrophobicContact CG2-CG2 4.49Å; S322-V326 WeakPolarHBondContact O-CG2 3.43Å; S322-V326 PolarHBondContact O-N 3.31Å; F323-V326 PolarHBondContact O-N 2.99Å; Q324-V326 VanDerWaalsContact C-N 3.28Å; Q324-V326 PolarHBondContact O-N 3.47Å; V326-L329 WeakPolarHBondContact O-CD1 3.34Å; V326-L329 VanDerWaalsContact O-CG 3.3Å; V326-L329 WeakPolarHBondContact O-CG 3.39Å
327	L	66.2	Low	55.6	Low	120 Å²	120	104.5 Å²	104.5	63%	0.628	56%	0.556	S	S	*	*	H	α-helix	trans	-73.5	-28.3	177	-72.9	-177.4	0	0	0	113	F323	F323-L327 HydrophobicContact CD1-CD1 3.48Å; F323-L327 VanDerWaalsContact CD1-CD1 3.48Å; F323-L327 HydrophobicContact CD1-CG 4.12Å; F323-L327 HydrophobicContact CE1-CD1 3.09Å; F323-L327 HydrophobicContact CE1-CG 4.01Å; F323-L327 HydrophobicContact CG-CD1 4.5Å; F323-L327 HydrophobicContact CZ-CD1 3.87Å; F323-L327 WeakPolarHBondContact O-CB 3.43Å; F323-L327 PolarHBondContact O-N 2.98Å
328	C	64.3	Low	54.6	Low	94 Å²	94	104.6 Å²	104.6	64%	0.635	56%	0.562	S	S	*	*	T	Hydrogen-bonded Turn	trans	-99.5	29.4	178.6	-53.8	0	0	0	0	112.8	Q324 K330	Q324-C328 WeakPolarHBondContact O-CA 3.32Å; Q324-C328 WeakPolarHBondContact O-CB 3.45Å; Q324-C328 PolarHBondContact O-N 3.1Å; Q324-C328 PolarHBondContact O-SG 3.05Å; C328-K330 VanDerWaalsContact C-N 3.27Å; C328-K330 PolarHBondContact O-N 3.26Å
329	L	55.3	Low	53.4	Low	127 Å²	127	107 Å²	107	67%	0.665	58%	0.576	S	S	*	*			trans	-62.8	75.6	-177.7	-84.8	169.5	0	0	0	114	N325 V326	N325-L329 WeakPolarHBondContact O-CD2 3.5Å; N325-L329 VanDerWaalsContact O-CG 3.25Å; N325-L329 WeakPolarHBondContact O-CG 3.27Å; V326-L329 WeakPolarHBondContact O-CD1 3.34Å; V326-L329 VanDerWaalsContact O-CG 3.3Å; V326-L329 WeakPolarHBondContact O-CG 3.39Å
330	K	46.6	Very low	52.2	Low	183 Å²	183	114.1 Å²	114.1	80%	0.796	60%	0.602	S	S	*	*			trans	160.3	89.8	139.9	-95	-177.1	174.9	179.4	0	109.1	C328 V332	C328-K330 VanDerWaalsContact C-N 3.27Å; C328-K330 PolarHBondContact O-N 3.26Å; K330-V332 HydrophobicContact CG-CG2 4.19Å
331	K	36.1	Very low	51	Low	205 Å²	205	112.4 Å²	112.4	89%	0.891	60%	0.602	S	S	*	*				-114.1	81.4	123.4	-149.7	174.5	-173.1	178.8	0	106.3	G333	K331-G333 PolarHBondContact O-N 3.44Å
332	V	47.4	Very low	49.8	Very low	135 Å²	135	112 Å²	112	82%	0.818	61%	0.606	S	S	*	*			trans	-62.8	113.8	157.6	168.2	0	0	0	0	104.8	K330	K330-V332 HydrophobicContact CG-CG2 4.19Å
333	G	36.1	Very low	48.8	Very low	64 Å²	64	114.7 Å²	114.7	66%	0.66	63%	0.625	S	S	*	*	S	Bend	trans	173.9	71.1	-177.9	0	0	0	0	0	110.2	K331	K331-G333 PolarHBondContact O-N 3.44Å
334	G	38.5	Very low	47.6	Very low	65 Å²	65	118.7 Å²	118.7	67%	0.67	64%	0.638	S	S	*	*			trans	68.2	89.3	156.1	0	0	0	0	0	117.3
335	L	42.7	Very low	46.4	Very low	144 Å²	144	119.9 Å²	119.9	75%	0.754	64%	0.644	S	S	*	*			trans	-137.3	16.9	157.3	-101.5	163.7	0	0	0	113.3	E337 V338	L335-E337 VanDerWaalsContact C-N 3.29Å; L335-V338 HydrophobicContact CD2-CB 4.39Å; L335-V338 HydrophobicContact CD2-CG2 3.83Å
336	D	41.2	Very low	45.2	Very low	164 Å²	164	121.1 Å²	121.1	88%	0.877	65%	0.65	S	S	*	*	S	Bend	trans	-85.9	4.4	166.7	-73.6	-27.7	0	0	0	112.7
337	E	40.9	Very low	44	Very low	163 Å²	163	127.5 Å²	127.5	76%	0.762	68%	0.676	S	S	*	*	S	Bend	trans	-99.1	-11.8	179	-93.5	-168.5	138.1	0	0	115.9	L335 S341	L335-E337 VanDerWaalsContact C-N 3.29Å; E337-S341 PolarHBondContact O-OG 3.08Å
338	V	42.7	Very low	42.8	Very low	98 Å²	98	125.3 Å²	125.3	59%	0.594	67%	0.67	S	S	*	*	S	Bend	trans	-85.7	-23.3	-175.4	-179.2	0	0	0	0	113	L335 S341	L335-V338 HydrophobicContact CD2-CB 4.39Å; L335-V338 HydrophobicContact CD2-CG2 3.83Å; V338-S341 PolarHBondContact O-OG 3.01Å
339	D	38.1	Very low	41.6	Very low	147 Å²	147	130.2 Å²	130.2	79%	0.786	68%	0.676	S	S	*	*	T	Hydrogen-bonded Turn	trans	-91.4	-6.4	-178.4	-127.2	0.8	0	0	0	113.5	S343	D339-S343 PolarHBondContact O-OG 3.35Å
340	R	38.3	Very low	41	Very low	158 Å²	158	132.3 Å²	132.3	60%	0.596	68%	0.684	S	S	*	*	T	Hydrogen-bonded Turn	trans	-104.3	-8.8	-178.4	-163.2	172.5	148.9	164	-5.2	113.7
341	S	39.5	Very low	40.9	Very low	60 Å²	60	131.3 Å²	131.3	42%	0.42	68%	0.684	S	S	.	*	T	Hydrogen-bonded Turn	trans	-86.7	-38.1	177	19.4	0	0	0	0	111.8	E337 V338 S343 R344 Q345	E337-S341 PolarHBondContact O-OG 3.08Å; V338-S341 PolarHBondContact O-OG 3.01Å; S341-S343 VanDerWaalsContact C-N 3.35Å; S341-S343 PolarHBondContact O-N 3.12Å; S341-R344 PolarHBondContact O-N 3.05Å; S341-Q345 WeakPolarHBondContact O-CB 3.41Å; S341-Q345 PolarHBondContact O-N 2.99Å
342	D	40.7	Very low	41.3	Very low	121 Å²	121	128 Å²	128	65%	0.647	68%	0.676	S	S	*	*	H	α-helix	trans	-65.5	-36.5	177.9	-110.9	-8.7	0	0	0	112.6	R344 D346	D342-R344 VanDerWaalsContact C-N 3.32Å; D342-R344 PolarHBondContact O-N 3.1Å; D342-D346 PolarHBondContact O-N 3.14Å
343	S	43	Very low	40.7	Very low	71 Å²	71	128.4 Å²	128.4	50%	0.497	67%	0.674	S	S	.	*	H	α-helix	trans	-76.8	-15	177.9	45.2	0	0	0	0	114.3	D339 S341	D339-S343 PolarHBondContact O-OG 3.35Å; S341-S343 VanDerWaalsContact C-N 3.35Å; S341-S343 PolarHBondContact O-N 3.12Å
344	R	42	Very low	41.2	Very low	158 Å²	158	130.4 Å²	130.4	60%	0.596	68%	0.675	S	S	*	*	H	α-helix	trans	-94.3	-31	173.4	-77.4	180	171.1	-168.6	-8.8	112.4	S341 D342 S348	S341-R344 PolarHBondContact O-N 3.05Å; D342-R344 VanDerWaalsContact C-N 3.32Å; D342-R344 PolarHBondContact O-N 3.1Å; R344-S348 WeakPolarHBondContact O-CB 3.17Å; R344-S348 PolarHBondContact O-N 2.82Å
345	Q	41.6	Very low	41.4	Very low	119 Å²	119	133.4 Å²	133.4	56%	0.556	68%	0.68	S	S	*	*	H	α-helix	trans	-74.9	-31	179.4	-148	160.5	7.8	0	0	111.9	S341 R349	S341-Q345 WeakPolarHBondContact O-CB 3.41Å; S341-Q345 PolarHBondContact O-N 2.99Å; Q345-R349 PolarHBondContact O-N 3.13Å
346	D	41.8	Very low	41.2	Very low	118 Å²	118	134.8 Å²	134.8	63%	0.631	68%	0.683	S	S	*	*	H	α-helix	trans	-74.7	-33.7	174.2	-136.4	13.8	0	0	0	112.6	D342 M350	D342-D346 PolarHBondContact O-N 3.14Å; D346-M350 PolarHBondContact O-N 3.28Å
347	K	41.1	Very low	40.9	Very low	164 Å²	164	133.4 Å²	133.4	71%	0.713	68%	0.681	S	S	*	*	H	α-helix	trans	-74.9	-30.3	172.5	-87.6	-172.5	174.1	-175	0	113.9
348	S	40.1	Very low	40.5	Very low	73 Å²	73	135 Å²	135	51%	0.51	69%	0.688	S	S	.	*	H	α-helix	trans	-75	-31.3	176.6	-166.7	0	0	0	0	112	R344 M351	R344-S348 WeakPolarHBondContact O-CB 3.17Å; R344-S348 PolarHBondContact O-N 2.82Å; S348-M351 PolarHBondContact O-N 2.84Å
349	R	40.4	Very low	40.1	Very low	198 Å²	198	135.2 Å²	135.2	75%	0.747	69%	0.694	S	S	*	*	H	α-helix	trans	-72.9	-25.7	173.9	-80.7	-178.5	173	177	-1.6	114.2	Q345 M351	Q345-R349 PolarHBondContact O-N 3.13Å; R349-M351 VanDerWaalsContact C-N 3.31Å
350	M	41.5	Very low	40	Very low	170 Å²	170	133.9 Å²	133.9	84%	0.837	69%	0.691	S	S	*	*	T	Hydrogen-bonded Turn	trans	-80.6	-6.2	173.5	-79.1	-176.2	70.8	0	0	114.2	D346	D346-M350 PolarHBondContact O-N 3.28Å
351	M	46.3	Very low	39.9	Very low	163 Å²	163	134.6 Å²	134.6	80%	0.803	71%	0.706	S	S	*	*	S	Bend	trans	-119	4.7	-173.3	-139	162.8	78.3	0	0	114.4	S348 R349	S348-M351 PolarHBondContact O-N 2.84Å; R349-M351 VanDerWaalsContact C-N 3.31Å
352	N	42.7	Very low	39.8	Very low	136 Å²	136	139.7 Å²	139.7	73%	0.727	73%	0.728	S	S	*	*			trans	-128.5	70	173	-88.2	-1.3	0	0	0	109.9
353	D	34.9	Very low	39.5	Very low	143 Å²	143	142.2 Å²	142.2	77%	0.765	74%	0.741	S	S	*	*			trans	-145.4	86.7	151.8	-159.4	18.3	0	0	0	108.6
354	P	46.9	Very low	39.2	Very low	105 Å²	105	142.2 Å²	142.2	68%	0.682	75%	0.752	S	S	*	*			trans	-77.3	138.6	158.4	29.9	-23.3	0	0	0	107.4
355	T	44.1	Very low	39.1	Very low	128 Å²	128	142.2 Å²	142.2	79%	0.785	76%	0.764	S	S	*	*			trans	100.4	77.5	167.7	-20.6	0	0	0	0	116.1
356	E	36.8	Very low	39	Very low	174 Å²	174	144.6 Å²	144.6	81%	0.813	78%	0.78	S	S	*	*			trans	-178.7	69.7	135.5	-105.8	-176.8	172.5	0	0	110.6
357	T	34.8	Very low	38.7	Very low	135 Å²	135	148.4 Å²	148.4	83%	0.828	79%	0.794	S	S	*	*	S	Bend	trans	-151.6	47.3	164.1	-22.7	0	0	0	0	111.5
358	Q	33.1	Very low	38.3	Very low	197 Å²	197	147.2 Å²	147.2	92%	0.921	80%	0.801	S	S	*	*	S	Bend	trans	-143.5	42.3	172.1	-148.6	171.6	3.2	0	0	112
359	S	34.9	Very low	38	Very low	101 Å²	101	149.5 Å²	149.5	71%	0.706	82%	0.816	S	S	*	*	S	Bend	trans	-134	11.9	174.8	54.3	0	0	0	0	114.2
360	T	35.9	Very low	37.9	Very low	120 Å²	120	151.7 Å²	151.7	74%	0.736	84%	0.841	S	S	*	*	S	Bend	trans	-126.2	11.7	-177.2	35.9	0	0	0	0	115.6
361	L	36.3	Very low	37.8	Very low	172 Å²	172	150.8 Å²	150.8	90%	0.901	84%	0.841	S	S	*	*	S	Bend	trans	-124.7	19.7	175.9	-78.7	173	0	0	0	114.9
362	L	36.3	Very low	37.3	Very low	168 Å²	168	150.2 Å²	150.2	88%	0.88	84%	0.843	S	S	*	*	S	Bend	trans	-137.3	51	172.6	-144	92.8	0	0	0	111.9
363	N	34.7	Very low	37	Very low	173 Å²	173	150.9 Å²	150.9	93%	0.925	85%	0.849	S	S	*	*	S	Bend	trans	-148.9	20.1	168.4	-109.2	-1.3	0	0	0	113.3
364	G	36.8	Very low	37.1	Very low	71 Å²	71	151.4 Å²	151.4	73%	0.732	85%	0.854	S	S	*	*	S	Bend	trans	-99.3	-18	-175.2	0	0	0	0	0	116.2
365	D	39.8	Very low	36.5	Very low	158 Å²	158	154.3 Å²	154.3	85%	0.845	87%	0.865	S	S	*	*	S	Bend	trans	-124	77.9	-172.3	-73.2	-36.7	0	0	0	111.4
366	L	40.6	Very low	36	Very low	170 Å²	170	156.1 Å²	156.1	89%	0.89	87%	0.87	S	S	*	*			trans	-167.5	78.1	149.5	-134.9	89	0	0	0	111.5
367	Q	34.7	Very low	36	Very low	197 Å²	197	154.8 Å²	154.8	92%	0.921	87%	0.874	S	S	*	*			trans	-167.7	79.5	154.1	-114	167.5	-1.3	0	0	113
368	T	33	Very low	36	Very low	140 Å²	140	156.3 Å²	156.3	86%	0.859	88%	0.878	S	S	*	*			trans	-141.8	100.2	150	47	0	0	0	0	109
369	S	32.8	Very low	36.3	Very low	120 Å²	120	152.9 Å²	152.9	84%	0.839	87%	0.874	S	S	*	*			trans	-169.1	89.1	159.3	-77.7	0	0	0	0	107.3
370	I	39.7	Very low	36.4	Very low	245 Å²	245	157.6 Å²	157.6	100%	1.256	89%	0.889	S	S	*	*				-152.9	0	129.6	-59.6	-164.3	0	0	0	106.4

Retrieved 370 of 370 residues in 262.2 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).