A0A087YSP8_POEFO Loading...

G protein-coupled receptor 63

AlphaFold DB , UniProt , Accession A0A087YSP8, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 376 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	38.6	Very low	35.8	Very low	223 Å²	223	145.2 Å²	145.2	100%	1.099	86%	0.857	S	S	*	*				0	77.8	0	-75.4	168.4	172	0	0	105.9
2	E	34.5	Very low	35.5	Very low	188 Å²	188	139.1 Å²	139.1	88%	0.879	85%	0.848	S	S	*	*				66.9	120.9	88.5	-68.4	171.9	126.5	0	0	110.2
3	G	33.4	Very low	35.2	Very low	78 Å²	78	137.7 Å²	137.7	80%	0.804	85%	0.848	S	S	*	*			cis	-170.6	159.2	5.2	0	0	0	0	0	110.8
4	V	39.4	Very low	35.3	Very low	127 Å²	127	133.4 Å²	133.4	77%	0.77	84%	0.844	S	S	*	*			trans	-76.9	161.2	167	-168.2	0	0	0	0	108	M6	V4-M6 HydrophobicContact CG1-CG 4.43Å
5	P	46.2	Very low	35.1	Very low	129 Å²	129	132.5 Å²	132.5	84%	0.838	84%	0.844	S	S	*	*				-140.9	146.3	91.7	28.5	-9	0	0	0	115.3
6	M	35	Very low	35.4	Very low	174 Å²	174	129.6 Å²	129.6	86%	0.857	84%	0.836	S	S	*	*			trans	-69.9	151.2	157.9	-73.3	-151.8	-71.5	0	0	111	V4	V4-M6 HydrophobicContact CG1-CG 4.43Å
7	A	33.9	Very low	35.6	Very low	94 Å²	94	129.6 Å²	129.6	78%	0.777	84%	0.836	S	S	*	*			trans	-153.3	106.5	147.6	0	0	0	0	0	112.1
8	N	30.1	Very low	35.7	Very low	155 Å²	155	132 Å²	132	83%	0.829	83%	0.834	S	S	*	*			trans	57.1	112.4	135	-65.6	-5.4	0	0	0	123.1
9	T	35.2	Very low	35.7	Very low	130 Å²	130	131.2 Å²	131.2	80%	0.798	83%	0.83	S	S	*	*			trans	-32.8	136.4	142.3	-12.8	0	0	0	0	115.8
10	S	31.4	Very low	36	Very low	124 Å²	124	131.8 Å²	131.8	87%	0.867	83%	0.832	S	S	*	*			trans	-143.6	125.6	138.8	63.6	0	0	0	0	110.9
11	L	36.5	Very low	35.9	Very low	175 Å²	175	128.8 Å²	128.8	92%	0.916	82%	0.82	S	S	*	*			trans	-80.7	135.4	176.6	-144.5	81.4	0	0	0	108.1
12	G	31.6	Very low	35.8	Very low	72 Å²	72	124.3 Å²	124.3	74%	0.742	81%	0.807	S	S	*	*			trans	-161.2	84.3	179.3	0	0	0	0	0	114.2
13	S	31.2	Very low	35.9	Very low	121 Å²	121	121.3 Å²	121.3	85%	0.846	80%	0.802	S	S	*	*			trans	37.9	121.1	144.9	-170.6	0	0	0	0	120.1
14	G	36.5	Very low	35.9	Very low	77 Å²	77	120.9 Å²	120.9	79%	0.794	80%	0.797	S	S	*	*			trans	-57.5	154.8	174.3	0	0	0	0	0	116.1
15	S	32.9	Very low	35.6	Very low	121 Å²	121	124.2 Å²	124.2	85%	0.846	80%	0.802	S	S	*	*			trans	-135.9	135.6	159.8	51	0	0	0	0	108.3
16	A	39.8	Very low	34.9	Very low	86 Å²	86	123.2 Å²	123.2	71%	0.711	80%	0.798	S	S	*	*			trans	-61.3	156.5	-169.6	0	0	0	0	0	114.1	Q18	A16-Q18 PolarHBondContact O-N 3.33Å; A16-Q18 VanDerWaalsContact O-N 3.16Å
17	P	39.2	Very low	34.8	Very low	130 Å²	130	119.9 Å²	119.9	84%	0.844	79%	0.792	S	S	*	*			trans	-67.4	114.8	169.8	27.1	-30.2	0	0	0	109.7
18	Q	36.6	Very low	34.9	Very low	172 Å²	172	120 Å²	120	80%	0.804	79%	0.792	S	S	*	*			trans	-58.7	137.5	168.4	-77	-98.4	-15.6	0	0	109.9	A16 V20	A16-Q18 PolarHBondContact O-N 3.33Å; A16-Q18 VanDerWaalsContact O-N 3.16Å; Q18-V20 PolarHBondContact O-N 3.46Å; Q18-V20 VanDerWaalsContact O-N 3.16Å
19	P	36.2	Very low	35.4	Very low	117 Å²	117	120.9 Å²	120.9	76%	0.76	79%	0.794	S	S	*	*			trans	-70.8	113.9	175.8	-0.6	15.5	0	0	0	108.8	A21	P19-A21 PolarHBondContact O-N 3.03Å
20	V	40.9	Very low	36	Very low	142 Å²	142	118.5 Å²	118.5	86%	0.861	79%	0.787	S	S	*	*			trans	-64.2	103.7	168.6	179	0	0	0	0	107.2	Q18	Q18-V20 PolarHBondContact O-N 3.46Å; Q18-V20 VanDerWaalsContact O-N 3.16Å
21	A	35.4	Very low	37	Very low	70 Å²	70	117.9 Å²	117.9	58%	0.579	78%	0.78	S	S	*	*			trans	-54.1	135.1	170.7	0	0	0	0	0	109.3	P19 T23	P19-A21 PolarHBondContact O-N 3.03Å; A21-T23 VanDerWaalsContact C-N 3.3Å; A21-T23 PolarHBondContact O-N 3Å
22	P	36.4	Very low	38.2	Very low	128 Å²	128	111.9 Å²	111.9	83%	0.831	76%	0.76	S	S	*	*			trans	-70.9	95.5	172	29.1	-29	0	0	0	106.6	G24	P22-G24 PolarHBondContact O-N 3.29Å
23	T	36	Very low	40.5	Very low	125 Å²	125	109.5 Å²	109.5	77%	0.767	73%	0.73	S	S	*	*			trans	-62.6	98.6	159.4	40.1	0	0	0	0	105.6	A21 K25	A21-T23 VanDerWaalsContact C-N 3.3Å; A21-T23 PolarHBondContact O-N 3Å; T23-K25 VanDerWaalsContact C-N 3.29Å; T23-K25 PolarHBondContact O-N 3.23Å
24	G	33.3	Very low	43.1	Very low	69 Å²	69	105.8 Å²	105.8	71%	0.711	71%	0.711	S	S	*	*			trans	-52.8	100.8	168.6	0	0	0	0	0	107.2	P22 S26	P22-G24 PolarHBondContact O-N 3.29Å; G24-S26 PolarHBondContact O-N 3.48Å
25	K	32.8	Very low	45.6	Very low	198 Å²	198	108 Å²	108	86%	0.861	70%	0.704	S	S	*	*			trans	-63	84.9	156	-73.1	-179.4	179.2	177.1	0	104.8	T23 S27	T23-K25 VanDerWaalsContact C-N 3.29Å; T23-K25 PolarHBondContact O-N 3.23Å; K25-S27 VanDerWaalsContact C-N 3.32Å; K25-S27 PolarHBondContact O-N 3.23Å
26	S	31.6	Very low	48.4	Very low	107 Å²	107	107.3 Å²	107.3	75%	0.748	70%	0.697	S	S	*	*			trans	-48	112.2	151.2	-177.8	0	0	0	0	104.3	G24 A28	G24-S26 PolarHBondContact O-N 3.48Å; S26-A28 PolarHBondContact O-N 3.32Å
27	S	33.9	Very low	50.8	Low	105 Å²	105	105.6 Å²	105.6	73%	0.734	68%	0.676	S	S	*	*			trans	-51.7	98.8	170.6	50.2	0	0	0	0	106	K25 M29	K25-S27 VanDerWaalsContact C-N 3.32Å; K25-S27 PolarHBondContact O-N 3.23Å; S27-M29 VanDerWaalsContact C-N 3.26Å; S27-M29 PolarHBondContact O-N 3.14Å
28	A	36	Very low	53.3	Low	96 Å²	96	101.2 Å²	101.2	79%	0.793	64%	0.644	S	S	*	*			trans	-60.4	101	175.5	0	0	0	0	0	105.8	S26 A30	S26-A28 PolarHBondContact O-N 3.32Å; A28-A30 PolarHBondContact O-N 2.81Å; A28-A30 VanDerWaalsContact O-N 3.16Å
29	M	40.1	Very low	56.1	Low	174 Å²	174	96.7 Å²	96.7	86%	0.857	63%	0.628	S	S	*	*			trans	-44.9	119.6	173.5	-169.5	155.7	172.5	0	0	106.8	S27	S27-M29 VanDerWaalsContact C-N 3.26Å; S27-M29 PolarHBondContact O-N 3.14Å
30	A	48.2	Very low	58.9	Low	80 Å²	80	95.5 Å²	95.5	66%	0.661	61%	0.611	S	S	*	*			trans	-45.2	135	174.3	0	0	0	0	0	108.2	A28 G32	A28-A30 PolarHBondContact O-N 2.81Å; A28-A30 VanDerWaalsContact O-N 3.16Å; A30-G32 VanDerWaalsContact C-N 3.34Å; A30-G32 PolarHBondContact O-N 3.29Å
31	P	51.2	Low	61.4	Low	111 Å²	111	88.8 Å²	88.8	72%	0.721	57%	0.57	S	S	*	*			trans	-60.3	100.5	-174.7	22.1	-30.5	0	0	0	108.8
32	G	62.7	Low	64.3	Low	48 Å²	48	86.3 Å²	86.3	50%	0.495	55%	0.548	S	S	.	.	P	Polyproline II helix	trans	-63.1	156.5	175.5	0	0	0	0	0	109.7	A30 G34	A30-G32 VanDerWaalsContact C-N 3.34Å; A30-G32 PolarHBondContact O-N 3.29Å; G32-G34 PolarHBondContact O-N 2.87Å
33	L	78.8	Confident	67.1	Low	22 Å²	22	85.6 Å²	85.6	12%	0.115	54%	0.537	C	S	.	.	P	Polyproline II helix	trans	-50.7	130.9	171.9	-165.5	73.8	0	0	0	109.6	L35 L37 Q38 F41 T102 Q308	L33-L35 PolarHBondContact O-N 3.23Å; L33-L37 HydrophobicContact CD1-CD2 3.39Å; L33-L37 HydrophobicContact CD1-CG 3.85Å; L33-L37 HydrophobicContact CD2-CG 4.18Å; L33-L37 HydrophobicContact CG-CB 4.18Å; L33-L37 HydrophobicContact CG-CD2 3.96Å; L33-L37 HydrophobicContact CG-CG 3.94Å; L33-Q38 HydrophobicContact CD2-CB 3.92Å; L33-Q38 HydrophobicContact CD2-CG 4.45Å; L33-Q38 HydrophobicContact CG-CB 4.41Å; L33-F41 HydrophobicContact CD1-CD2 4.4Å; L33-F41 HydrophobicContact CD1-CE2 3.97Å; L33-F41 HydrophobicContact CD2-CD2 3.25Å; L33-F41 HydrophobicContact CD2-CE2 3.69Å; L33-F41 HydrophobicContact CD2-CG 4.14Å; L33-F41 HydrophobicContact CG-CD2 4.42Å; L33-F41 HydrophobicContact CG-CE2 4.46Å; L33-T102 HydrophobicContact CB-CG2 4.33Å; L33-Q308 HydrophobicContact CD1-CB 4.02Å; L33-Q308 HydrophobicContact CD1-CG 4.08Å
34	G	86.6	Confident	69.9	Low	43 Å²	43	81.5 Å²	81.5	44%	0.443	51%	0.512	S	S	.	.	P	Polyproline II helix	trans	-55.1	138.5	179.6	0	0	0	0	0	111.5	G32 P36 L37 Q38	G32-G34 PolarHBondContact O-N 2.87Å; G34-P36 VanDerWaalsContact C-CD 3.44Å; G34-L37 WeakPolarHBondContact O-CA 3.3Å; G34-L37 WeakPolarHBondContact O-CB 3.46Å; G34-L37 PolarHBondContact O-N 3.43Å; G34-Q38 PolarHBondContact O-N 3.07Å
35	L	88.1	Confident	72.8	Confident	123 Å²	123	78.3 Å²	78.3	64%	0.644	48%	0.478	S	S	*	.	H	α-helix	trans	-50.1	-44.4	-173	-176.5	69.5	0	0	0	114.1	L33 L37 Q38 V39	L33-L35 PolarHBondContact O-N 3.23Å; L35-L37 VanDerWaalsContact C-N 3.31Å; L35-L37 PolarHBondContact O-N 3.47Å; L35-Q38 PolarHBondContact O-N 3.43Å; L35-V39 HydrophobicContact CD1-CG2 4.46Å; L35-V39 WeakPolarHBondContact O-CG2 3.46Å; L35-V39 PolarHBondContact O-N 3.49Å
36	P	92.1	Very high	75.9	Confident	108 Å²	108	70.3 Å²	70.3	70%	0.701	45%	0.45	S	S	*	.	H	α-helix	trans	-62	-39.6	177.7	-22.4	34.3	0	0	0	112.8	G34 V39 F40	G34-P36 VanDerWaalsContact C-CD 3.44Å; P36-V39 PolarHBondContact O-N 3.19Å; P36-F40 WeakPolarHBondContact O-CB 3.45Å; P36-F40 PolarHBondContact O-N 3.06Å
37	L	90.1	Very high	78.9	Confident	49 Å²	49	69.2 Å²	69.2	26%	0.257	44%	0.439	S	S	.	.	H	α-helix	trans	-70.4	-37.2	179.4	-176	59.5	0	0	0	111.1	L33 G34 L35 F40 F41 Q308	L33-L37 HydrophobicContact CD1-CD2 3.39Å; L33-L37 HydrophobicContact CD1-CG 3.85Å; L33-L37 HydrophobicContact CD2-CG 4.18Å; L33-L37 HydrophobicContact CG-CB 4.18Å; L33-L37 HydrophobicContact CG-CD2 3.96Å; L33-L37 HydrophobicContact CG-CG 3.94Å; G34-L37 WeakPolarHBondContact O-CA 3.3Å; G34-L37 WeakPolarHBondContact O-CB 3.46Å; G34-L37 PolarHBondContact O-N 3.43Å; L35-L37 VanDerWaalsContact C-N 3.31Å; L35-L37 PolarHBondContact O-N 3.47Å; L37-F40 HydrophobicContact CD1-CD1 4.25Å; L37-F41 HydrophobicContact CD1-CD1 3.94Å; L37-F41 HydrophobicContact CD1-CE1 3.55Å; L37-F41 HydrophobicContact CD1-CE2 4.29Å; L37-F41 HydrophobicContact CD1-CZ 3.73Å; L37-F41 HydrophobicContact CD2-CE2 4.5Å; L37-F41 HydrophobicContact CD2-CZ 4.42Å; L37-F41 HydrophobicContact CG-CD1 4.45Å; L37-F41 HydrophobicContact CG-CD2 4.43Å; L37-F41 HydrophobicContact CG-CE1 4.23Å; L37-F41 HydrophobicContact CG-CE2 4.1Å; L37-F41 HydrophobicContact CG-CZ 4.04Å; L37-F41 VanDerWaalsContact O-CB 3.24Å; L37-F41 WeakPolarHBondContact O-CB 3.36Å; L37-F41 WeakPolarHBondContact O-CD1 3.31Å; L37-F41 WeakPolarHBondContact O-CG 3.43Å; L37-F41 PolarHBondContact O-N 3.5Å; L37-Q308 HydrophobicContact CD2-CG 4.21Å
38	Q	92.8	Very high	81.9	Confident	39 Å²	39	64.9 Å²	64.9	18%	0.182	41%	0.407	C	S	.	.	H	α-helix	trans	-65	-42.7	174	-173.4	-174.9	-33.9	0	0	112.7	L33 G34 L35 F41 S42 V99 M100	L33-Q38 HydrophobicContact CD2-CB 3.92Å; L33-Q38 HydrophobicContact CD2-CG 4.45Å; L33-Q38 HydrophobicContact CG-CB 4.41Å; G34-Q38 PolarHBondContact O-N 3.07Å; L35-Q38 PolarHBondContact O-N 3.43Å; Q38-F41 PolarHBondContact O-N 3.26Å; Q38-S42 WeakPolarHBondContact O-CB 3.37Å; Q38-S42 PolarHBondContact O-N 3.48Å; Q38-S42 PolarHBondContact O-OG 2.99Å; Q38-V99 WeakPolarHBondContact CG-O 3.47Å; Q38-M100 PolarHBondContact NE2-O 3.05Å
39	V	94.8	Very high	84.8	Confident	76 Å²	76	61.7 Å²	61.7	46%	0.461	38%	0.376	S	S	.	.	H	α-helix	trans	-63.9	-49.6	175.2	170.9	0	0	0	0	110.4	L35 P36 F41 S42 L43	L35-V39 HydrophobicContact CD1-CG2 4.46Å; L35-V39 WeakPolarHBondContact O-CG2 3.46Å; L35-V39 PolarHBondContact O-N 3.49Å; P36-V39 PolarHBondContact O-N 3.19Å; V39-F41 PolarHBondContact O-N 3.35Å; V39-S42 PolarHBondContact O-N 3.09Å; V39-L43 HydrophobicContact CG1-CD1 3.92Å; V39-L43 HydrophobicContact CG1-CG 4.4Å; V39-L43 WeakPolarHBondContact O-CG 3.34Å; V39-L43 PolarHBondContact O-N 3.32Å
40	F	95	Very high	87.5	Confident	93 Å²	93	59 Å²	59	41%	0.408	37%	0.365	S	S	.	.	H	α-helix	trans	-53.7	-44.4	173.7	171.7	-107.2	0	0	0	110.5	P36 L37 S42 L43 V44 W312 W315	P36-F40 WeakPolarHBondContact O-CB 3.45Å; P36-F40 PolarHBondContact O-N 3.06Å; L37-F40 HydrophobicContact CD1-CD1 4.25Å; F40-S42 PolarHBondContact O-N 3.23Å; F40-L43 PolarHBondContact O-N 2.88Å; F40-V44 HydrophobicContact CD2-CG2 4.19Å; F40-V44 HydrophobicContact CE1-CG2 4.42Å; F40-V44 HydrophobicContact CE2-CG2 3.76Å; F40-V44 HydrophobicContact CZ-CG2 3.87Å; F40-V44 WeakPolarHBondContact O-CG2 3.37Å; F40-V44 PolarHBondContact O-N 3.43Å; F40-V44 VanDerWaalsContact O-N 3.14Å; F40-W312 AromaticContact CE1-CH2 3.65Å; F40-W312 HydrophobicContact CE1-CH2 3.65Å; F40-W312 HydrophobicContact CE1-CZ2 4.17Å; F40-W312 HydrophobicContact CE1-CZ3 4.4Å; F40-W312 HydrophobicContact CZ-CH2 4.2Å; F40-W315 HydrophobicContact CD1-CH2 4.11Å; F40-W315 AromaticContact CE1-CH2 3.79Å; F40-W315 HydrophobicContact CE1-CH2 3.79Å; F40-W315 AromaticContact CE1-CZ3 3.84Å; F40-W315 HydrophobicContact CE1-CZ3 3.84Å; F40-W315 HydrophobicContact CZ-CH2 4.46Å; F40-W315 HydrophobicContact CZ-CZ3 4.34Å
41	F	93.9	Very high	89.7	Confident	0 Å²	0	57.8 Å²	57.8	0%	0	35%	0.349	C	S	.	.	H	α-helix	trans	-64.2	-43.7	-179.1	-78.9	0.2	0	0	0	114	L33 L37 Q38 V39 M45 V99 Q308 T311 W312 W315	L33-F41 HydrophobicContact CD1-CD2 4.4Å; L33-F41 HydrophobicContact CD1-CE2 3.97Å; L33-F41 HydrophobicContact CD2-CD2 3.25Å; L33-F41 HydrophobicContact CD2-CE2 3.69Å; L33-F41 HydrophobicContact CD2-CG 4.14Å; L33-F41 HydrophobicContact CG-CD2 4.42Å; L33-F41 HydrophobicContact CG-CE2 4.46Å; L37-F41 HydrophobicContact CD1-CD1 3.94Å; L37-F41 HydrophobicContact CD1-CE1 3.55Å; L37-F41 HydrophobicContact CD1-CE2 4.29Å; L37-F41 HydrophobicContact CD1-CZ 3.73Å; L37-F41 HydrophobicContact CD2-CE2 4.5Å; L37-F41 HydrophobicContact CD2-CZ 4.42Å; L37-F41 HydrophobicContact CG-CD1 4.45Å; L37-F41 HydrophobicContact CG-CD2 4.43Å; L37-F41 HydrophobicContact CG-CE1 4.23Å; L37-F41 HydrophobicContact CG-CE2 4.1Å; L37-F41 HydrophobicContact CG-CZ 4.04Å; L37-F41 VanDerWaalsContact O-CB 3.24Å; L37-F41 WeakPolarHBondContact O-CB 3.36Å; L37-F41 WeakPolarHBondContact O-CD1 3.31Å; L37-F41 WeakPolarHBondContact O-CG 3.43Å; L37-F41 PolarHBondContact O-N 3.5Å; Q38-F41 PolarHBondContact O-N 3.26Å; V39-F41 PolarHBondContact O-N 3.35Å; F41-M45 WeakPolarHBondContact O-CB 3.44Å; F41-M45 PolarHBondContact O-N 2.94Å; F41-M45 VanDerWaalsContact O-N 3.11Å; F41-V99 HydrophobicContact CB-CG1 3.65Å; F41-Q308 HydrophobicContact CE2-CG 4.05Å; F41-Q308 HydrophobicContact CZ-CG 3.98Å; F41-T311 HydrophobicContact CB-CG2 4.37Å; F41-T311 HydrophobicContact CD2-CG2 3.41Å; F41-T311 VanDerWaalsContact CD2-CG2 3.41Å; F41-T311 HydrophobicContact CE2-CG2 3.71Å; F41-T311 HydrophobicContact CG-CG2 3.93Å; F41-T311 HydrophobicContact CZ-CG2 4.39Å; F41-W312 HydrophobicContact CE1-CD2 4.14Å; F41-W312 AromaticContact CE1-CE2 3.61Å; F41-W312 HydrophobicContact CE1-CH2 4.25Å; F41-W312 AromaticContact CE1-CZ2 3.67Å; F41-W312 HydrophobicContact CE1-CZ2 3.67Å; F41-W312 AromaticContact CE1-NE1 3.9Å; F41-W312 AromaticContact CZ-CD1 3.9Å; F41-W312 HydrophobicContact CZ-CD2 4.24Å; F41-W312 AromaticContact CZ-CE2 3.72Å; F41-W312 HydrophobicContact CZ-CG 4.35Å; F41-W312 HydrophobicContact CZ-CZ2 4.19Å; F41-W312 AromaticContact CZ-NE1 3.5Å; F41-W315 VanDerWaalsContact CA-CH2 3.47Å; F41-W315 HydrophobicContact CB-CH2 3.96Å; F41-W315 HydrophobicContact CB-CZ2 3.44Å; F41-W315 VanDerWaalsContact CB-CZ2 3.44Å; F41-W315 AromaticContact CD1-CH2 3Å; F41-W315 HydrophobicContact CD1-CH2 3Å; F41-W315 AromaticContact CD1-CZ2 3.28Å; F41-W315 HydrophobicContact CD1-CZ2 3.28Å; F41-W315 AromaticContact CD1-CZ3 3.84Å; F41-W315 HydrophobicContact CD1-CZ3 3.84Å; F41-W315 HydrophobicContact CD2-CZ2 4.41Å; F41-W315 AromaticContact CE1-CH2 3.59Å; F41-W315 HydrophobicContact CE1-CH2 3.59Å; F41-W315 HydrophobicContact CE1-CZ2 4.04Å; F41-W315 AromaticContact CE1-CZ3 3.96Å; F41-W315 HydrophobicContact CE1-CZ3 3.96Å; F41-W315 AromaticContact CG-CH2 3.72Å; F41-W315 HydrophobicContact CG-CH2 3.72Å; F41-W315 AromaticContact CG-CZ2 3.46Å; F41-W315 HydrophobicContact CG-CZ2 3.46Å; F41-W315 VanDerWaalsContact CG-CZ2 3.46Å; F41-W315 WeakPolarHBondContact O-CZ2 3.35Å
42	S	95.1	Very high	91.8	Very high	18 Å²	18	52.5 Å²	52.5	13%	0.126	32%	0.315	C	S	.	.	H	α-helix	trans	-65.5	-42.5	179.9	-54.4	0	0	0	0	111.3	Q38 V39 F40 M45 A46 L96 M100	Q38-S42 WeakPolarHBondContact O-CB 3.37Å; Q38-S42 PolarHBondContact O-N 3.48Å; Q38-S42 PolarHBondContact O-OG 2.99Å; V39-S42 PolarHBondContact O-N 3.09Å; F40-S42 PolarHBondContact O-N 3.23Å; S42-M45 PolarHBondContact O-N 3.33Å; S42-A46 VanDerWaalsContact O-CB 3.29Å; S42-A46 WeakPolarHBondContact O-CB 3.08Å; S42-A46 PolarHBondContact O-N 2.99Å; S42-L96 WeakPolarHBondContact O-CD1 3.33Å; S42-M100 VanDerWaalsContact OG-CG 3.32Å; S42-M100 WeakPolarHBondContact OG-CG 3.41Å
43	L	95.9	Very high	93.4	Very high	113 Å²	113	52.9 Å²	52.9	59%	0.592	31%	0.305	S	S	*	.	H	α-helix	trans	-63.3	-44.3	179.5	-71.9	172.8	0	0	0	112.7	V39 F40 T47	V39-L43 HydrophobicContact CG1-CD1 3.92Å; V39-L43 HydrophobicContact CG1-CG 4.4Å; V39-L43 WeakPolarHBondContact O-CG 3.34Å; V39-L43 PolarHBondContact O-N 3.32Å; F40-L43 PolarHBondContact O-N 2.88Å; L43-T47 WeakPolarHBondContact O-CB 3.5Å; L43-T47 PolarHBondContact O-N 2.91Å; L43-T47 PolarHBondContact O-OG1 2.93Å
44	V	95.1	Very high	94	Very high	40 Å²	40	54.7 Å²	54.7	24%	0.242	32%	0.323	C	S	.	.	H	α-helix	trans	-64.7	-46.7	178.1	173.2	0	0	0	0	110.5	F40 A46 T47 I48 W315	F40-V44 HydrophobicContact CD2-CG2 4.19Å; F40-V44 HydrophobicContact CE1-CG2 4.42Å; F40-V44 HydrophobicContact CE2-CG2 3.76Å; F40-V44 HydrophobicContact CZ-CG2 3.87Å; F40-V44 WeakPolarHBondContact O-CG2 3.37Å; F40-V44 PolarHBondContact O-N 3.43Å; F40-V44 VanDerWaalsContact O-N 3.14Å; V44-A46 PolarHBondContact O-N 3.46Å; V44-T47 PolarHBondContact O-N 3.26Å; V44-I48 HydrophobicContact CG1-CD1 3.89Å; V44-I48 HydrophobicContact CG1-CG1 4.48Å; V44-I48 WeakPolarHBondContact O-CG1 3.41Å; V44-I48 PolarHBondContact O-N 2.81Å; V44-W315 HydrophobicContact CB-CH2 3.57Å; V44-W315 HydrophobicContact CB-CZ2 3.96Å; V44-W315 HydrophobicContact CB-CZ3 3.99Å; V44-W315 HydrophobicContact CG1-CD2 4.15Å; V44-W315 HydrophobicContact CG1-CE3 3.92Å; V44-W315 HydrophobicContact CG1-CH2 3.83Å; V44-W315 HydrophobicContact CG1-CZ2 4.22Å; V44-W315 HydrophobicContact CG1-CZ3 3.75Å; V44-W315 HydrophobicContact CG2-CH2 3.93Å; V44-W315 HydrophobicContact CG2-CZ3 4.22Å
45	M	94.7	Very high	94.3	Very high	1 Å²	1	53.4 Å²	53.4	1%	0.005	31%	0.31	C	S	.	.	H	α-helix	trans	-65.4	-38.8	180	-169.7	178.7	-64.8	0	0	112.1	F41 S42 T47 I48 L49 A95 L96 V99 L314 Y318	F41-M45 WeakPolarHBondContact O-CB 3.44Å; F41-M45 PolarHBondContact O-N 2.94Å; F41-M45 VanDerWaalsContact O-N 3.11Å; S42-M45 PolarHBondContact O-N 3.33Å; M45-T47 VanDerWaalsContact C-N 3.33Å; M45-T47 PolarHBondContact O-N 2.87Å; M45-I48 PolarHBondContact O-N 2.91Å; M45-L49 WeakPolarHBondContact O-CB 3.44Å; M45-L49 PolarHBondContact O-N 3.3Å; M45-A95 HydrophobicContact CE-CB 4.41Å; M45-A95 HydrophobicContact SD-CB 3.9Å; M45-L96 HydrophobicContact CB-CD1 4.17Å; M45-L96 HydrophobicContact CG-CB 4.35Å; M45-L96 WeakPolarHBondContact SD-CA 3.24Å; M45-L96 HydrophobicContact SD-CB 3.83Å; M45-L96 PolarHBondContact SD-N 3.26Å; M45-V99 HydrophobicContact CE-CG2 3.59Å; M45-V99 HydrophobicContact SD-CG2 4.34Å; M45-L314 HydrophobicContact CE-CD2 4.37Å; M45-Y318 HydrophobicContact SD-CE2 4.45Å
46	A	96.8	Very high	94.6	Very high	31 Å²	31	47.6 Å²	47.6	26%	0.256	28%	0.279	S	S	.	.	H	α-helix	trans	-62.1	-40.6	173.4	0	0	0	0	0	111.9	S42 V44 L49 L50 L96	S42-A46 VanDerWaalsContact O-CB 3.29Å; S42-A46 WeakPolarHBondContact O-CB 3.08Å; S42-A46 PolarHBondContact O-N 2.99Å; V44-A46 PolarHBondContact O-N 3.46Å; A46-L49 WeakPolarHBondContact O-CB 3.4Å; A46-L49 PolarHBondContact O-N 3.27Å; A46-L50 VanDerWaalsContact O-CG 3.32Å; A46-L50 WeakPolarHBondContact O-CG 3.43Å; A46-L50 PolarHBondContact O-N 3.43Å; A46-L96 HydrophobicContact CB-CD2 4.13Å
47	T	96.1	Very high	94.6	Very high	84 Å²	84	44.9 Å²	44.9	52%	0.515	26%	0.261	S	S	.	.	H	α-helix	trans	-64.8	-46	176.4	-55.7	0	0	0	0	111.4	L43 V44 M45 L49 L50 V51	L43-T47 WeakPolarHBondContact O-CB 3.5Å; L43-T47 PolarHBondContact O-N 2.91Å; L43-T47 PolarHBondContact O-OG1 2.93Å; V44-T47 PolarHBondContact O-N 3.26Å; M45-T47 VanDerWaalsContact C-N 3.33Å; M45-T47 PolarHBondContact O-N 2.87Å; T47-L49 VanDerWaalsContact C-N 3.33Å; T47-L49 PolarHBondContact O-N 2.7Å; T47-L50 PolarHBondContact O-N 3.01Å; T47-V51 HydrophobicContact CG2-CG2 4.44Å; T47-V51 WeakPolarHBondContact O-CG2 3.43Å; T47-V51 PolarHBondContact O-N 2.99Å
48	I	96.3	Very high	94.5	Very high	14 Å²	14	44.3 Å²	44.3	7%	0.072	26%	0.259	C	S	.	.	H	α-helix	trans	-59	-45.6	176.6	-68.6	168.8	0	0	0	110.6	V44 M45 L50 V51 A52 M92 W315 Y318 L319 A322	V44-I48 HydrophobicContact CG1-CD1 3.89Å; V44-I48 HydrophobicContact CG1-CG1 4.48Å; V44-I48 WeakPolarHBondContact O-CG1 3.41Å; V44-I48 PolarHBondContact O-N 2.81Å; M45-I48 PolarHBondContact O-N 2.91Å; I48-L50 PolarHBondContact O-N 3.09Å; I48-V51 PolarHBondContact O-N 2.78Å; I48-A52 WeakPolarHBondContact O-CB 3.31Å; I48-A52 PolarHBondContact O-N 3.1Å; I48-M92 HydrophobicContact CG2-SD 4.44Å; I48-W315 HydrophobicContact CD1-CB 4.36Å; I48-Y318 WeakPolarHBondContact CG2-O 3.36Å; I48-L319 HydrophobicContact CD1-CB 4.32Å; I48-L319 HydrophobicContact CD1-CD1 4.47Å; I48-L319 HydrophobicContact CG1-CD1 4.3Å; I48-A322 HydrophobicContact CG2-CB 4.23Å
49	L	96.7	Very high	94.3	Very high	29 Å²	29	42.6 Å²	42.6	15%	0.152	25%	0.252	C	S	.	.	H	α-helix	trans	-55.1	-51.7	176.5	167.5	67.1	0	0	0	111.5	M45 A46 T47 A52 L53 A88 M92 P93	M45-L49 WeakPolarHBondContact O-CB 3.44Å; M45-L49 PolarHBondContact O-N 3.3Å; A46-L49 WeakPolarHBondContact O-CB 3.4Å; A46-L49 PolarHBondContact O-N 3.27Å; T47-L49 VanDerWaalsContact C-N 3.33Å; T47-L49 PolarHBondContact O-N 2.7Å; L49-A52 PolarHBondContact O-N 3Å; L49-L53 VanDerWaalsContact O-CB 3.28Å; L49-L53 WeakPolarHBondContact O-CB 2.97Å; L49-L53 PolarHBondContact O-N 2.97Å; L49-A88 HydrophobicContact CD1-CB 4.21Å; L49-A88 WeakPolarHBondContact CD1-O 3.49Å; L49-M92 HydrophobicContact CB-CB 4.46Å; L49-M92 HydrophobicContact CB-SD 4.35Å; L49-M92 HydrophobicContact CD1-CB 3.81Å; L49-M92 HydrophobicContact CD1-SD 4.28Å; L49-P93 HydrophobicContact CD1-CG 4.27Å; L49-P93 HydrophobicContact CD2-CG 4.38Å
50	L	95.9	Very high	94.1	Very high	117 Å²	117	39.5 Å²	39.5	61%	0.613	23%	0.233	S	C	*	.	H	α-helix	trans	-63.7	-44.9	-177.7	-69.7	173.1	0	0	0	112	A46 T47 I48 A54	A46-L50 VanDerWaalsContact O-CG 3.32Å; A46-L50 WeakPolarHBondContact O-CG 3.43Å; A46-L50 PolarHBondContact O-N 3.43Å; T47-L50 PolarHBondContact O-N 3.01Å; I48-L50 PolarHBondContact O-N 3.09Å; L50-A54 VanDerWaalsContact O-CB 3.26Å; L50-A54 WeakPolarHBondContact O-CB 3.5Å; L50-A54 PolarHBondContact O-N 2.7Å
51	V	94.9	Very high	93.7	Very high	54 Å²	54	38.3 Å²	38.3	33%	0.327	23%	0.231	S	C	.	.	H	α-helix	trans	-66.2	-44.6	179	175.7	0	0	0	0	111	T47 I48 G55 A322 L326	T47-V51 HydrophobicContact CG2-CG2 4.44Å; T47-V51 WeakPolarHBondContact O-CG2 3.43Å; T47-V51 PolarHBondContact O-N 2.99Å; I48-V51 PolarHBondContact O-N 2.78Å; V51-G55 WeakPolarHBondContact O-CA 3.26Å; V51-G55 PolarHBondContact O-N 2.96Å; V51-A322 HydrophobicContact CB-CB 4.13Å; V51-A322 HydrophobicContact CG1-CB 3.86Å; V51-L326 HydrophobicContact CG1-CD1 4.27Å; V51-L326 HydrophobicContact CG1-CG 4.49Å
52	A	95.8	Very high	93.1	Very high	0 Å²	0	38.6 Å²	38.6	0%	0	23%	0.232	C	C	.	.	H	α-helix	trans	-61.6	-47.1	177.4	0	0	0	0	0	111.2	I48 L49 N56 A88 M92 A322	I48-A52 WeakPolarHBondContact O-CB 3.31Å; I48-A52 PolarHBondContact O-N 3.1Å; L49-A52 PolarHBondContact O-N 3Å; A52-N56 VanDerWaalsContact O-CB 3.25Å; A52-N56 WeakPolarHBondContact O-CB 3.45Å; A52-N56 PolarHBondContact O-N 2.93Å; A52-N56 VanDerWaalsContact O-N 3.07Å; A52-N56 PolarHBondContact O-ND2 3.22Å; A52-A88 HydrophobicContact CB-CB 4.23Å; A52-M92 HydrophobicContact CB-CE 4.22Å; A52-M92 HydrophobicContact CB-SD 4.48Å; A52-A322 HydrophobicContact CB-CB 4.14Å
53	L	95.6	Very high	92.5	Very high	57 Å²	57	38.4 Å²	38.4	30%	0.298	23%	0.23	S	C	.	.	H	α-helix	trans	-64.7	-55	-179.6	-176.8	59	0	0	0	111.4	L49 G55 N56 V57 M85 I89	L49-L53 VanDerWaalsContact O-CB 3.28Å; L49-L53 WeakPolarHBondContact O-CB 2.97Å; L49-L53 PolarHBondContact O-N 2.97Å; L53-G55 PolarHBondContact O-N 3.34Å; L53-N56 PolarHBondContact O-N 3.02Å; L53-V57 HydrophobicContact CD1-CG2 4.23Å; L53-V57 WeakPolarHBondContact O-CB 3.48Å; L53-V57 WeakPolarHBondContact O-CG2 3.42Å; L53-V57 PolarHBondContact O-N 3.34Å; L53-M85 HydrophobicContact CD1-CG 3.88Å; L53-I89 HydrophobicContact CD1-CD1 3.94Å; L53-I89 HydrophobicContact CD1-CG1 3.79Å
54	A	92.1	Very high	91.7	Very high	60 Å²	60	40 Å²	40	50%	0.496	23%	0.23	S	C	.	.	H	α-helix	trans	-62.1	-46.3	-177.4	0	0	0	0	0	111.9	L50 V58	L50-A54 VanDerWaalsContact O-CB 3.26Å; L50-A54 WeakPolarHBondContact O-CB 3.5Å; L50-A54 PolarHBondContact O-N 2.7Å; A54-V58 WeakPolarHBondContact O-CG2 3.5Å; A54-V58 PolarHBondContact O-N 2.99Å; A54-V58 VanDerWaalsContact O-N 3.15Å
55	G	91.8	Very high	90.9	Very high	16 Å²	16	43.8 Å²	43.8	17%	0.165	24%	0.244	C	C	.	.	H	α-helix	trans	-63.2	-46.6	-178.8	0	0	0	0	0	112.5	V51 L53 V58 V59	V51-G55 WeakPolarHBondContact O-CA 3.26Å; V51-G55 PolarHBondContact O-N 2.96Å; L53-G55 PolarHBondContact O-N 3.34Å; G55-V58 PolarHBondContact O-N 3.31Å; G55-V59 WeakPolarHBondContact O-CG2 3.41Å; G55-V59 PolarHBondContact O-N 3.37Å; G55-V59 VanDerWaalsContact O-N 3.08Å
56	N	94.6	Very high	90	Very high	0 Å²	0	49.9 Å²	49.9	0%	0	27%	0.267	C	S	.	.	H	α-helix	trans	-72.5	-32.8	-178	-72.2	-62.2	0	0	0	112.5	A52 L53 V58 V59 C60 A81 M85 S321 P325	A52-N56 VanDerWaalsContact O-CB 3.25Å; A52-N56 WeakPolarHBondContact O-CB 3.45Å; A52-N56 PolarHBondContact O-N 2.93Å; A52-N56 VanDerWaalsContact O-N 3.07Å; A52-N56 PolarHBondContact O-ND2 3.22Å; L53-N56 PolarHBondContact O-N 3.02Å; N56-V58 VanDerWaalsContact C-N 3.32Å; N56-V58 PolarHBondContact O-N 2.92Å; N56-V59 PolarHBondContact O-N 2.93Å; N56-C60 PolarHBondContact O-N 3.43Å; N56-C60 PolarHBondContact O-SG 3.11Å; N56-A81 HydrophobicContact CB-CB 4.07Å; N56-A81 WeakPolarHBondContact CB-O 3.29Å; N56-A81 WeakPolarHBondContact OD1-CA 3.48Å; N56-M85 HydrophobicContact CB-CB 4.19Å; N56-S321 PolarHBondContact ND2-O 3.21Å; N56-P325 HydrophobicContact CB-CG 4.41Å; N56-P325 WeakPolarHBondContact OD1-CG 3.29Å
57	V	92	Very high	88.6	Confident	51 Å²	51	52.7 Å²	52.7	31%	0.309	29%	0.285	S	S	.	.	H	α-helix	trans	-57.5	-46.8	169.8	167.1	0	0	0	0	110.7	L53 V59 C60 L61 M85	L53-V57 HydrophobicContact CD1-CG2 4.23Å; L53-V57 WeakPolarHBondContact O-CB 3.48Å; L53-V57 WeakPolarHBondContact O-CG2 3.42Å; L53-V57 PolarHBondContact O-N 3.34Å; V57-V59 PolarHBondContact O-N 3.15Å; V57-C60 PolarHBondContact O-N 3.18Å; V57-L61 HydrophobicContact CG1-CD1 3.86Å; V57-L61 HydrophobicContact CG1-CG 4.27Å; V57-L61 WeakPolarHBondContact O-CG 3.44Å; V57-L61 PolarHBondContact O-N 3.2Å; V57-M85 HydrophobicContact CG2-CG 4.41Å; V57-M85 HydrophobicContact CG2-SD 3.56Å; V57-M85 VanDerWaalsContact CG2-SD 3.56Å
58	V	89	Confident	87.2	Confident	38 Å²	38	53.2 Å²	53.2	23%	0.23	30%	0.298	C	S	.	.	H	α-helix	trans	-60.4	-44.6	177.4	171.3	0	0	0	0	111	A54 G55 N56 C60 L61 M62 F335 C339 L342	A54-V58 WeakPolarHBondContact O-CG2 3.5Å; A54-V58 PolarHBondContact O-N 2.99Å; A54-V58 VanDerWaalsContact O-N 3.15Å; G55-V58 PolarHBondContact O-N 3.31Å; N56-V58 VanDerWaalsContact C-N 3.32Å; N56-V58 PolarHBondContact O-N 2.92Å; V58-C60 PolarHBondContact O-N 3.05Å; V58-L61 PolarHBondContact O-N 3.29Å; V58-M62 HydrophobicContact CG1-CG 4.21Å; V58-M62 HydrophobicContact CG1-SD 3.64Å; V58-M62 WeakPolarHBondContact O-CB 3.31Å; V58-M62 WeakPolarHBondContact O-CG 3.28Å; V58-M62 PolarHBondContact O-N 3.26Å; V58-F335 HydrophobicContact CG1-CZ 4.44Å; V58-C339 VanDerWaalsContact CG1-SG 3.56Å; V58-L342 HydrophobicContact CG2-CD2 4.48Å
59	V	89.1	Confident	85.9	Confident	3 Å²	3	54 Å²	54	2%	0.018	30%	0.301	C	S	.	.	H	α-helix	trans	-56.9	-48.3	176.6	178.5	0	0	0	0	111.5	G55 N56 V57 M62 V63 A81 P325 Y328 F335	G55-V59 WeakPolarHBondContact O-CG2 3.41Å; G55-V59 PolarHBondContact O-N 3.37Å; G55-V59 VanDerWaalsContact O-N 3.08Å; N56-V59 PolarHBondContact O-N 2.93Å; V57-V59 PolarHBondContact O-N 3.15Å; V59-M62 PolarHBondContact O-N 2.94Å; V59-V63 PolarHBondContact O-N 3.32Å; V59-A81 HydrophobicContact CB-CB 3.66Å; V59-A81 HydrophobicContact CG1-CB 3.54Å; V59-A81 HydrophobicContact CG2-CB 4.39Å; V59-P325 HydrophobicContact CG2-CB 4.11Å; V59-P325 HydrophobicContact CG2-CG 4.18Å; V59-Y328 HydrophobicContact CG1-CD2 4.42Å; V59-Y328 HydrophobicContact CG1-CE2 4.5Å; V59-Y328 HydrophobicContact CG2-CD2 3.8Å; V59-Y328 HydrophobicContact CG2-CE2 4.3Å; V59-F335 HydrophobicContact CB-CE2 4.07Å; V59-F335 HydrophobicContact CB-CZ 4.23Å; V59-F335 HydrophobicContact CG1-CE2 4.2Å; V59-F335 HydrophobicContact CG2-CE2 3.61Å; V59-F335 HydrophobicContact CG2-CZ 3.4Å; V59-F335 VanDerWaalsContact CG2-CZ 3.4Å
60	C	89.8	Confident	85	Confident	11 Å²	11	59.4 Å²	59.4	7%	0.074	32%	0.32	C	S	.	.	H	α-helix	trans	-60.9	-51.8	178.4	-68.8	0	0	0	0	111.4	N56 V57 V58 M62 V63 Y64	N56-C60 PolarHBondContact O-N 3.43Å; N56-C60 PolarHBondContact O-SG 3.11Å; V57-C60 PolarHBondContact O-N 3.18Å; V58-C60 PolarHBondContact O-N 3.05Å; C60-M62 VanDerWaalsContact C-N 3.27Å; C60-M62 PolarHBondContact O-N 2.79Å; C60-V63 PolarHBondContact O-N 3.39Å; C60-Y64 HydrophobicContact CB-CD2 4.34Å; C60-Y64 HydrophobicContact CB-CE2 4.23Å; C60-Y64 WeakPolarHBondContact O-CD2 3.37Å; C60-Y64 PolarHBondContact O-N 3.06Å; C60-Y64 VanDerWaalsContact O-N 3.12Å
61	L	86.2	Confident	84.5	Confident	68 Å²	68	56 Å²	56	36%	0.356	31%	0.306	S	S	.	.	H	α-helix	trans	-55.4	-44.1	-179	-72.8	175.7	0	0	0	112	V57 V58 V63 Y64 Q65 L342	V57-L61 HydrophobicContact CG1-CD1 3.86Å; V57-L61 HydrophobicContact CG1-CG 4.27Å; V57-L61 WeakPolarHBondContact O-CG 3.44Å; V57-L61 PolarHBondContact O-N 3.2Å; V58-L61 PolarHBondContact O-N 3.29Å; L61-V63 PolarHBondContact O-N 3.01Å; L61-Y64 PolarHBondContact O-N 3.25Å; L61-Q65 VanDerWaalsContact O-CB 3.3Å; L61-Q65 WeakPolarHBondContact O-CB 3.4Å; L61-Q65 VanDerWaalsContact O-CG 3.28Å; L61-Q65 WeakPolarHBondContact O-CG 3.28Å; L61-Q65 PolarHBondContact O-N 2.97Å; L61-L342 HydrophobicContact CD1-CD2 4.19Å
62	M	81.1	Confident	84.2	Confident	6 Å²	6	54 Å²	54	3%	0.03	30%	0.295	C	S	.	.	H	α-helix	trans	-61.6	-40.4	-178.3	-75.3	178.4	59.5	0	0	113.6	V58 V59 C60 R66 F335 A338	V58-M62 HydrophobicContact CG1-CG 4.21Å; V58-M62 HydrophobicContact CG1-SD 3.64Å; V58-M62 WeakPolarHBondContact O-CB 3.31Å; V58-M62 WeakPolarHBondContact O-CG 3.28Å; V58-M62 PolarHBondContact O-N 3.26Å; V59-M62 PolarHBondContact O-N 2.94Å; C60-M62 VanDerWaalsContact C-N 3.27Å; C60-M62 PolarHBondContact O-N 2.79Å; M62-R66 WeakPolarHBondContact O-CB 3.25Å; M62-R66 PolarHBondContact O-N 3.31Å; M62-F335 VanDerWaalsContact CE-CA 3.49Å; M62-F335 HydrophobicContact CE-CB 4.09Å; M62-F335 HydrophobicContact CE-CD1 4.32Å; M62-F335 HydrophobicContact CE-CD2 3.46Å; M62-F335 VanDerWaalsContact CE-CD2 3.46Å; M62-F335 HydrophobicContact CE-CE2 3.86Å; M62-F335 HydrophobicContact CE-CG 3.7Å; M62-F335 HydrophobicContact CE-CZ 4.45Å; M62-F335 VanDerWaalsContact CE-O 3.3Å; M62-F335 WeakPolarHBondContact CE-O 3.38Å; M62-F335 HydrophobicContact SD-CD1 4.36Å; M62-F335 HydrophobicContact SD-CD2 3.84Å; M62-F335 HydrophobicContact SD-CE1 4.19Å; M62-F335 HydrophobicContact SD-CE2 3.58Å; M62-F335 VanDerWaalsContact SD-CE2 3.58Å; M62-F335 HydrophobicContact SD-CG 4.21Å; M62-F335 HydrophobicContact SD-CZ 3.76Å; M62-A338 HydrophobicContact CE-CB 3.31Å; M62-A338 HydrophobicContact CG-CB 4.47Å; M62-A338 HydrophobicContact SD-CB 4.31Å
63	V	82.4	Confident	83.8	Confident	14 Å²	14	55.3 Å²	55.3	9%	0.085	30%	0.301	C	S	.	.	H	α-helix	trans	-75	-37.3	180	177.2	0	0	0	0	111.3	V59 C60 L61 N74 A78	V59-V63 PolarHBondContact O-N 3.32Å; C60-V63 PolarHBondContact O-N 3.39Å; L61-V63 PolarHBondContact O-N 3.01Å; V63-N74 HydrophobicContact CG1-CB 4.33Å; V63-N74 HydrophobicContact CG2-CB 4.24Å; V63-A78 HydrophobicContact CB-CB 3.87Å; V63-A78 HydrophobicContact CG1-CB 3.85Å; V63-A78 HydrophobicContact CG2-CB 4.03Å
64	Y	79.3	Confident	83.4	Confident	147 Å²	147	53.7 Å²	53.7	58%	0.576	29%	0.293	S	S	*	.	H	α-helix	trans	-72.9	-42.2	-179.7	-72.5	-61.1	0	0	0	113.1	C60 L61 R70	C60-Y64 HydrophobicContact CB-CD2 4.34Å; C60-Y64 HydrophobicContact CB-CE2 4.23Å; C60-Y64 WeakPolarHBondContact O-CD2 3.37Å; C60-Y64 PolarHBondContact O-N 3.06Å; C60-Y64 VanDerWaalsContact O-N 3.12Å; L61-Y64 PolarHBondContact O-N 3.25Å; Y64-R70 PolarHBondContact O-NH2 3.28Å
65	Q	78.6	Confident	83.4	Confident	118 Å²	118	52.2 Å²	52.2	55%	0.551	28%	0.276	S	S	*	.	H	α-helix	trans	-75.9	-31.2	-175.2	-69.4	179.8	-7.4	0	0	113.5	L61	L61-Q65 VanDerWaalsContact O-CB 3.3Å; L61-Q65 WeakPolarHBondContact O-CB 3.4Å; L61-Q65 VanDerWaalsContact O-CG 3.28Å; L61-Q65 WeakPolarHBondContact O-CG 3.28Å; L61-Q65 PolarHBondContact O-N 2.97Å
66	R	75	Confident	83.4	Confident	130 Å²	130	51.4 Å²	51.4	49%	0.491	27%	0.269	S	S	.	.			trans	-103.8	105.4	-174.8	-59.6	-65	-168.3	168	5.5	111.1	M62 A68 M69	M62-R66 WeakPolarHBondContact O-CB 3.25Å; M62-R66 PolarHBondContact O-N 3.31Å; R66-A68 PolarHBondContact O-N 3.42Å; R66-M69 HydrophobicContact CB-CB 4.16Å; R66-M69 HydrophobicContact CB-CG 3.98Å; R66-M69 WeakPolarHBondContact O-CB 3.47Å; R66-M69 PolarHBondContact O-N 3.4Å
67	S	69	Low	83.3	Confident	90 Å²	90	52.1 Å²	52.1	63%	0.629	27%	0.272	S	S	*	.	G	3₁₀ helix	trans	-55.6	-36.5	176.1	58.5	0	0	0	0	113	M69 R70	S67-M69 PolarHBondContact O-N 2.78Å; S67-M69 VanDerWaalsContact O-N 3.1Å; S67-R70 WeakPolarHBondContact O-CB 3.34Å; S67-R70 PolarHBondContact O-N 2.92Å; S67-R70 VanDerWaalsContact O-N 3.09Å
68	A	65.3	Low	83.3	Confident	95 Å²	95	49.8 Å²	49.8	79%	0.785	26%	0.258	S	S	*	.	G	3₁₀ helix	trans	-62.3	-14.2	175.7	0	0	0	0	0	114.3	R66	R66-A68 PolarHBondContact O-N 3.42Å
69	M	69.1	Low	83.6	Confident	29 Å²	29	48.8 Å²	48.8	14%	0.143	25%	0.252	C	S	.	.	G	3₁₀ helix	trans	-103.8	7.9	178.4	-65.9	-68.1	-76.9	0	0	112.7	R66 S67 S71 N74 K334	R66-M69 HydrophobicContact CB-CB 4.16Å; R66-M69 HydrophobicContact CB-CG 3.98Å; R66-M69 WeakPolarHBondContact O-CB 3.47Å; R66-M69 PolarHBondContact O-N 3.4Å; S67-M69 PolarHBondContact O-N 2.78Å; S67-M69 VanDerWaalsContact O-N 3.1Å; M69-S71 PolarHBondContact O-N 3.2Å; M69-N74 WeakPolarHBondContact O-CB 3.35Å; M69-N74 PolarHBondContact O-ND2 3.12Å; M69-K334 HydrophobicContact CE-CB 4.41Å; M69-K334 HydrophobicContact SD-CB 4.44Å; M69-K334 HydrophobicContact SD-CD 4.19Å
70	R	78.3	Confident	83.9	Confident	144 Å²	144	48.6 Å²	48.6	54%	0.543	25%	0.251	S	S	.	.			trans	-83.1	43.9	-179.6	-63.1	179.5	-178.1	168.9	-0.4	113.7	Y64 S67	Y64-R70 PolarHBondContact O-NH2 3.28Å; S67-R70 WeakPolarHBondContact O-CB 3.34Å; S67-R70 PolarHBondContact O-N 2.92Å; S67-R70 VanDerWaalsContact O-N 3.09Å
71	S	85.8	Confident	84.1	Confident	46 Å²	46	48.1 Å²	48.1	32%	0.322	25%	0.247	S	C	.	.			trans	-76.7	159	171.2	67	0	0	0	0	110.9	M69 I73 N74 I75	M69-S71 PolarHBondContact O-N 3.2Å; S71-I73 VanDerWaalsContact C-N 3.28Å; S71-I73 PolarHBondContact O-N 2.97Å; S71-I73 VanDerWaalsContact OG-CG2 3.31Å; S71-I73 WeakPolarHBondContact OG-CG2 3.4Å; S71-N74 PolarHBondContact O-N 3.43Å; S71-N74 VanDerWaalsContact O-N 3.11Å; S71-N74 WeakPolarHBondContact OG-CB 3.42Å; S71-N74 PolarHBondContact OG-N 3.4Å; S71-N74 PolarHBondContact OG-ND2 3.13Å; S71-I75 WeakPolarHBondContact O-CG1 3.46Å; S71-I75 PolarHBondContact O-N 2.95Å
72	A	87.4	Confident	84.6	Confident	10 Å²	10	48.2 Å²	48.2	8%	0.083	25%	0.245	C	C	.	.	H	α-helix	trans	-55.8	-42.5	-179.6	0	0	0	0	0	112.5	I75 L76 L147 P149 A152	A72-I75 PolarHBondContact O-N 3.41Å; A72-L76 WeakPolarHBondContact O-CG 3.44Å; A72-L76 PolarHBondContact O-N 3.24Å; A72-L76 VanDerWaalsContact O-N 3.15Å; A72-L147 HydrophobicContact CB-CD2 3.97Å; A72-L147 HydrophobicContact CB-CG 3.86Å; A72-L147 WeakPolarHBondContact CB-O 3.49Å; A72-P149 HydrophobicContact CB-CG 4.37Å; A72-A152 HydrophobicContact CB-CB 4.07Å
73	I	87.3	Confident	85.4	Confident	28 Å²	28	48 Å²	48	14%	0.144	24%	0.244	C	C	.	.	H	α-helix	trans	-64.2	-41.6	176.8	-174.7	67.3	0	0	0	112.6	S71 I75 L76 L77 I132	S71-I73 VanDerWaalsContact C-N 3.28Å; S71-I73 PolarHBondContact O-N 2.97Å; S71-I73 VanDerWaalsContact OG-CG2 3.31Å; S71-I73 WeakPolarHBondContact OG-CG2 3.4Å; I73-I75 VanDerWaalsContact C-N 3.28Å; I73-I75 PolarHBondContact O-N 2.93Å; I73-L76 WeakPolarHBondContact O-CB 3.47Å; I73-L76 PolarHBondContact O-N 2.95Å; I73-L77 HydrophobicContact CG1-CD1 4.28Å; I73-L77 HydrophobicContact CG1-CG 4.4Å; I73-L77 WeakPolarHBondContact O-CG 3.06Å; I73-L77 PolarHBondContact O-N 3.04Å; I73-I132 HydrophobicContact CD1-CB 4.26Å; I73-I132 HydrophobicContact CD1-CD1 4.06Å; I73-I132 HydrophobicContact CD1-CG1 3.69Å; I73-I132 HydrophobicContact CD1-CG2 3.78Å
74	N	88	Confident	86.1	Confident	23 Å²	23	47.4 Å²	47.4	12%	0.123	24%	0.24	C	C	.	.	H	α-helix	trans	-69.8	-30.7	-178.7	-71.8	-10	0	0	0	111.3	V63 M69 S71 L77 A78	V63-N74 HydrophobicContact CG1-CB 4.33Å; V63-N74 HydrophobicContact CG2-CB 4.24Å; M69-N74 WeakPolarHBondContact O-CB 3.35Å; M69-N74 PolarHBondContact O-ND2 3.12Å; S71-N74 PolarHBondContact O-N 3.43Å; S71-N74 VanDerWaalsContact O-N 3.11Å; S71-N74 WeakPolarHBondContact OG-CB 3.42Å; S71-N74 PolarHBondContact OG-N 3.4Å; S71-N74 PolarHBondContact OG-ND2 3.13Å; N74-L77 PolarHBondContact O-N 3.38Å; N74-A78 WeakPolarHBondContact O-CB 3.37Å; N74-A78 PolarHBondContact O-N 2.99Å
75	I	91.8	Very high	86.9	Confident	29 Å²	29	41.8 Å²	41.8	15%	0.149	22%	0.219	C	C	.	.	H	α-helix	trans	-63.7	-44.7	170.8	-66.8	167.6	0	0	0	110.4	S71 A72 I73 A78 N79 P149 K153 I156	S71-I75 WeakPolarHBondContact O-CG1 3.46Å; S71-I75 PolarHBondContact O-N 2.95Å; A72-I75 PolarHBondContact O-N 3.41Å; I73-I75 VanDerWaalsContact C-N 3.28Å; I73-I75 PolarHBondContact O-N 2.93Å; I75-A78 PolarHBondContact O-N 3.39Å; I75-N79 PolarHBondContact O-N 3.13Å; I75-P149 HydrophobicContact CD1-CB 3.87Å; I75-K153 HydrophobicContact CG2-CG 4.38Å; I75-I156 HydrophobicContact CG2-CD1 3.68Å
76	L	93.1	Very high	87.7	Confident	0 Å²	0	38 Å²	38	0%	0	20%	0.202	C	C	.	.	H	α-helix	trans	-62	-44.9	175	-67.1	174.2	0	0	0	111.7	A72 I73 A78 N79 L80 I128 I131 I132 L147 A152 I156	A72-L76 WeakPolarHBondContact O-CG 3.44Å; A72-L76 PolarHBondContact O-N 3.24Å; A72-L76 VanDerWaalsContact O-N 3.15Å; I73-L76 WeakPolarHBondContact O-CB 3.47Å; I73-L76 PolarHBondContact O-N 2.95Å; L76-A78 VanDerWaalsContact C-N 3.32Å; L76-A78 PolarHBondContact O-N 3.39Å; L76-N79 PolarHBondContact O-N 3.31Å; L76-L80 PolarHBondContact O-N 3.28Å; L76-I128 HydrophobicContact CB-CG2 4.01Å; L76-I128 HydrophobicContact CD2-CD1 3.91Å; L76-I128 HydrophobicContact CD2-CG2 4.49Å; L76-I128 WeakPolarHBondContact O-CG2 3.25Å; L76-I131 HydrophobicContact CD1-CG2 3.71Å; L76-I131 HydrophobicContact CD2-CG2 4.27Å; L76-I132 HydrophobicContact CB-CD1 4.19Å; L76-I132 HydrophobicContact CB-CG1 4.16Å; L76-I132 HydrophobicContact CD1-CG1 3.99Å; L76-L147 HydrophobicContact CD1-CD2 3.84Å; L76-A152 HydrophobicContact CD2-CB 4.3Å; L76-A152 HydrophobicContact CG-CB 4.26Å; L76-I156 HydrophobicContact CD2-CD1 4.07Å; L76-I156 HydrophobicContact CD2-CG1 3.91Å
77	L	91.1	Very high	88.8	Confident	15 Å²	15	31.9 Å²	31.9	8%	0.079	18%	0.179	C	C	.	.	H	α-helix	trans	-62.4	-37.4	176.2	-66.9	175.3	0	0	0	112.4	I73 N74 L80 A81 I132 Y328 I332	I73-L77 HydrophobicContact CG1-CD1 4.28Å; I73-L77 HydrophobicContact CG1-CG 4.4Å; I73-L77 WeakPolarHBondContact O-CG 3.06Å; I73-L77 PolarHBondContact O-N 3.04Å; N74-L77 PolarHBondContact O-N 3.38Å; L77-L80 PolarHBondContact O-N 2.94Å; L77-A81 WeakPolarHBondContact O-CB 3.12Å; L77-A81 PolarHBondContact O-N 3.48Å; L77-I132 HydrophobicContact CD2-CD1 3.85Å; L77-Y328 HydrophobicContact CD2-CE1 3.78Å; L77-Y328 WeakPolarHBondContact CD2-OH 3.28Å; L77-I332 HydrophobicContact CD1-CD1 4.5Å
78	A	92.3	Very high	90.1	Very high	2 Å²	2	27.6 Å²	27.6	2%	0.017	15%	0.149	C	C	.	.	H	α-helix	trans	-67.1	-38	174.8	0	0	0	0	0	112.4	V63 N74 I75 L76 A81 F82	V63-A78 HydrophobicContact CB-CB 3.87Å; V63-A78 HydrophobicContact CG1-CB 3.85Å; V63-A78 HydrophobicContact CG2-CB 4.03Å; N74-A78 WeakPolarHBondContact O-CB 3.37Å; N74-A78 PolarHBondContact O-N 2.99Å; I75-A78 PolarHBondContact O-N 3.39Å; L76-A78 VanDerWaalsContact C-N 3.32Å; L76-A78 PolarHBondContact O-N 3.39Å; A78-A81 PolarHBondContact O-N 2.86Å; A78-F82 WeakPolarHBondContact O-CB 3.44Å; A78-F82 PolarHBondContact O-N 2.86Å
79	N	95.8	Very high	91.6	Very high	16 Å²	16	26.6 Å²	26.6	9%	0.086	13%	0.13	C	C	.	.	H	α-helix	trans	-66.9	-41.4	174.5	-173.3	70.3	0	0	0	111.6	I75 L76 A81 F82 A83 E124 I128 I156 W160	I75-N79 PolarHBondContact O-N 3.13Å; L76-N79 PolarHBondContact O-N 3.31Å; N79-A81 PolarHBondContact O-N 2.84Å; N79-F82 WeakPolarHBondContact O-CB 3.4Å; N79-F82 PolarHBondContact O-N 3.03Å; N79-A83 PolarHBondContact O-N 2.98Å; N79-E124 PolarHBondContact ND2-OE1 3.48Å; N79-I128 VanDerWaalsContact ND2-CD1 3.27Å; N79-I128 WeakPolarHBondContact ND2-CD1 3.35Å; N79-I128 WeakPolarHBondContact ND2-CG1 3.33Å; N79-I156 HydrophobicContact CB-CD1 3.84Å; N79-I156 HydrophobicContact CB-CG1 4.17Å; N79-I156 HydrophobicContact CB-CG2 4.5Å; N79-I156 WeakPolarHBondContact OD1-CG2 3.49Å; N79-W160 PolarHBondContact OD1-NE1 2.86Å
80	L	94.6	Very high	93	Very high	0 Å²	0	28 Å²	28	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-58.8	-46.3	173.1	179.8	59.5	0	0	0	111.6	L76 L77 F82 A83 D84 G125 I128 L129 Y328	L76-L80 PolarHBondContact O-N 3.28Å; L77-L80 PolarHBondContact O-N 2.94Å; L80-F82 VanDerWaalsContact C-N 3.33Å; L80-F82 PolarHBondContact O-N 3.35Å; L80-A83 PolarHBondContact O-N 3.24Å; L80-D84 PolarHBondContact O-N 2.95Å; L80-G125 VanDerWaalsContact CD1-CA 3.48Å; L80-G125 WeakPolarHBondContact CD1-O 3.3Å; L80-I128 HydrophobicContact CB-CG2 3.97Å; L80-L129 HydrophobicContact CD2-CD2 3.78Å; L80-L129 HydrophobicContact CD2-CG 4.11Å; L80-Y328 WeakPolarHBondContact CD2-OH 3.49Å
81	A	95.2	Very high	93.8	Very high	0 Å²	0	21.1 Å²	21.1	0%	0	11%	0.112	C	C	.	.	H	α-helix	trans	-63.6	-37.9	175.8	0	0	0	0	0	112.5	N56 V59 L77 A78 N79 D84 M85	N56-A81 HydrophobicContact CB-CB 4.07Å; N56-A81 WeakPolarHBondContact CB-O 3.29Å; N56-A81 WeakPolarHBondContact OD1-CA 3.48Å; V59-A81 HydrophobicContact CB-CB 3.66Å; V59-A81 HydrophobicContact CG1-CB 3.54Å; V59-A81 HydrophobicContact CG2-CB 4.39Å; L77-A81 WeakPolarHBondContact O-CB 3.12Å; L77-A81 PolarHBondContact O-N 3.48Å; A78-A81 PolarHBondContact O-N 2.86Å; N79-A81 PolarHBondContact O-N 2.84Å; A81-D84 PolarHBondContact O-N 3.35Å; A81-M85 VanDerWaalsContact O-CB 3.28Å; A81-M85 WeakPolarHBondContact O-CB 3.3Å; A81-M85 PolarHBondContact O-N 3.42Å
82	F	96.3	Very high	94.4	Very high	71 Å²	71	19 Å²	19	31%	0.311	10%	0.097	S	C	.	.	H	α-helix	trans	-63	-44.5	175.3	177.2	-99.6	0	0	0	111.9	A78 N79 L80 M85 M86 W160	A78-F82 WeakPolarHBondContact O-CB 3.44Å; A78-F82 PolarHBondContact O-N 2.86Å; N79-F82 WeakPolarHBondContact O-CB 3.4Å; N79-F82 PolarHBondContact O-N 3.03Å; L80-F82 VanDerWaalsContact C-N 3.33Å; L80-F82 PolarHBondContact O-N 3.35Å; F82-M85 HydrophobicContact CD2-CE 3.66Å; F82-M85 HydrophobicContact CE2-CE 4Å; F82-M85 WeakPolarHBondContact O-CB 3.44Å; F82-M85 PolarHBondContact O-N 3.22Å; F82-M86 HydrophobicContact CD1-CG 4.42Å; F82-M86 HydrophobicContact CD2-CE 4.49Å; F82-M86 HydrophobicContact CE1-CG 3.99Å; F82-M86 HydrophobicContact CE2-CE 3.92Å; F82-M86 HydrophobicContact CE2-CG 4.23Å; F82-M86 HydrophobicContact CE2-SD 4.4Å; F82-M86 HydrophobicContact CZ-CE 4.31Å; F82-M86 HydrophobicContact CZ-CG 3.88Å; F82-M86 HydrophobicContact CZ-SD 4.2Å; F82-M86 WeakPolarHBondContact O-CG 3.28Å; F82-M86 PolarHBondContact O-N 3.36Å; F82-W160 HydrophobicContact CD1-CH2 4.32Å; F82-W160 AromaticContact CD1-CZ2 3.84Å; F82-W160 HydrophobicContact CD1-CZ2 3.84Å; F82-W160 HydrophobicContact CE1-CH2 4.04Å; F82-W160 AromaticContact CE1-CZ2 3.87Å; F82-W160 HydrophobicContact CE1-CZ2 3.87Å
83	A	97.1	Very high	94.8	Very high	0 Å²	0	20.5 Å²	20.5	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-62.6	-44.3	175.3	0	0	0	0	0	112.1	N79 L80 M85 M86 L87 F121 E124	N79-A83 PolarHBondContact O-N 2.98Å; L80-A83 PolarHBondContact O-N 3.24Å; A83-M85 VanDerWaalsContact C-N 3.33Å; A83-M85 PolarHBondContact O-N 3.26Å; A83-M86 PolarHBondContact O-N 2.82Å; A83-L87 WeakPolarHBondContact O-CB 3.47Å; A83-L87 PolarHBondContact O-N 3.42Å; A83-F121 HydrophobicContact CB-CB 4.46Å; A83-F121 HydrophobicContact CB-CD1 4.43Å; A83-E124 HydrophobicContact CB-CB 4.45Å; A83-E124 HydrophobicContact CB-CG 4.18Å
84	D	96.8	Very high	95.3	Very high	2 Å²	2	21.9 Å²	21.9	1%	0.011	11%	0.111	C	C	.	.	H	α-helix	trans	-64.1	-36.9	176.9	-74.9	-21.8	0	0	0	112.1	L80 A81 L87 A88 K320 S321 N324	L80-D84 PolarHBondContact O-N 2.95Å; A81-D84 PolarHBondContact O-N 3.35Å; D84-L87 PolarHBondContact O-N 2.93Å; D84-A88 WeakPolarHBondContact O-CB 3.04Å; D84-A88 PolarHBondContact O-N 2.96Å; D84-K320 IonicContact OD1-NZ 2.65Å; D84-K320 PolarHBondContact OD1-NZ 2.88Å; D84-K320 IonicContact OD2-NZ 3.39Å; D84-K320 PolarHBondContact OD2-NZ 3.18Å; D84-S321 PolarHBondContact OD1-OG 3.26Å; D84-N324 PolarHBondContact OD2-ND2 3.12Å
85	M	96.1	Very high	95.7	Very high	29 Å²	29	20.8 Å²	20.8	14%	0.143	11%	0.105	C	C	.	.	H	α-helix	trans	-64.3	-45.8	173.1	178.8	177.3	75.9	0	0	111.6	L53 N56 V57 A81 F82 A83 L87 A88 I89	L53-M85 HydrophobicContact CD1-CG 3.88Å; N56-M85 HydrophobicContact CB-CB 4.19Å; V57-M85 HydrophobicContact CG2-CG 4.41Å; V57-M85 HydrophobicContact CG2-SD 3.56Å; V57-M85 VanDerWaalsContact CG2-SD 3.56Å; A81-M85 VanDerWaalsContact O-CB 3.28Å; A81-M85 WeakPolarHBondContact O-CB 3.3Å; A81-M85 PolarHBondContact O-N 3.42Å; F82-M85 HydrophobicContact CD2-CE 3.66Å; F82-M85 HydrophobicContact CE2-CE 4Å; F82-M85 WeakPolarHBondContact O-CB 3.44Å; F82-M85 PolarHBondContact O-N 3.22Å; A83-M85 VanDerWaalsContact C-N 3.33Å; A83-M85 PolarHBondContact O-N 3.26Å; M85-L87 VanDerWaalsContact C-N 3.33Å; M85-L87 PolarHBondContact O-N 3.4Å; M85-A88 WeakPolarHBondContact O-CB 3.3Å; M85-A88 PolarHBondContact O-N 3.22Å; M85-I89 HydrophobicContact CG-CD1 3.87Å; M85-I89 WeakPolarHBondContact O-CG1 3.36Å; M85-I89 PolarHBondContact O-N 3.22Å
86	M	97.3	Very high	95.9	Very high	38 Å²	38	20.7 Å²	20.7	19%	0.187	11%	0.105	C	C	.	.	H	α-helix	trans	-64.5	-38.3	176.7	-69.4	-61.2	108.8	0	0	111.9	F82 A83 A88 I89 L90 F121	F82-M86 HydrophobicContact CD1-CG 4.42Å; F82-M86 HydrophobicContact CD2-CE 4.49Å; F82-M86 HydrophobicContact CE1-CG 3.99Å; F82-M86 HydrophobicContact CE2-CE 3.92Å; F82-M86 HydrophobicContact CE2-CG 4.23Å; F82-M86 HydrophobicContact CE2-SD 4.4Å; F82-M86 HydrophobicContact CZ-CE 4.31Å; F82-M86 HydrophobicContact CZ-CG 3.88Å; F82-M86 HydrophobicContact CZ-SD 4.2Å; F82-M86 WeakPolarHBondContact O-CG 3.28Å; F82-M86 PolarHBondContact O-N 3.36Å; A83-M86 PolarHBondContact O-N 2.82Å; M86-A88 VanDerWaalsContact C-N 3.33Å; M86-A88 PolarHBondContact O-N 3.46Å; M86-I89 HydrophobicContact CE-CD1 3.97Å; M86-I89 PolarHBondContact O-N 3.48Å; M86-L90 HydrophobicContact CB-CD1 4.39Å; M86-L90 VanDerWaalsContact O-CB 3.27Å; M86-L90 WeakPolarHBondContact O-CB 3.36Å; M86-L90 WeakPolarHBondContact O-CG 3.38Å; M86-L90 PolarHBondContact O-N 2.9Å; M86-L90 HydrophobicContact SD-CD1 4.39Å; M86-F121 HydrophobicContact CB-CD1 3.8Å; M86-F121 HydrophobicContact CB-CD2 4.08Å; M86-F121 HydrophobicContact CB-CE1 3.41Å; M86-F121 VanDerWaalsContact CB-CE1 3.41Å; M86-F121 HydrophobicContact CB-CE2 3.73Å; M86-F121 HydrophobicContact CB-CG 4.15Å; M86-F121 HydrophobicContact CB-CZ 3.39Å; M86-F121 HydrophobicContact CG-CE1 3.94Å; M86-F121 HydrophobicContact CG-CZ 4.11Å
87	L	96.8	Very high	96.1	Very high	3 Å²	3	23 Å²	23	2%	0.016	12%	0.119	C	C	.	.	H	α-helix	trans	-61	-42.5	172.3	-176.9	65.8	0	0	0	111.6	A83 D84 M85 I89 N91 M92 F118 F121 Y318	A83-L87 WeakPolarHBondContact O-CB 3.47Å; A83-L87 PolarHBondContact O-N 3.42Å; D84-L87 PolarHBondContact O-N 2.93Å; M85-L87 VanDerWaalsContact C-N 3.33Å; M85-L87 PolarHBondContact O-N 3.4Å; L87-I89 VanDerWaalsContact C-N 3.35Å; L87-N91 HydrophobicContact CD1-CB 4.03Å; L87-N91 WeakPolarHBondContact O-CB 3.4Å; L87-N91 PolarHBondContact O-N 3.44Å; L87-N91 VanDerWaalsContact O-N 3.14Å; L87-M92 HydrophobicContact CG-CE 4.43Å; L87-M92 PolarHBondContact O-N 2.75Å; L87-F118 HydrophobicContact CD1-CD2 3.89Å; L87-F118 HydrophobicContact CD1-CE2 4.49Å; L87-F121 HydrophobicContact CB-CB 4.06Å; L87-F121 HydrophobicContact CB-CD2 4.3Å; L87-F121 HydrophobicContact CB-CG 4.47Å; L87-F121 HydrophobicContact CD1-CB 4.5Å; L87-Y318 HydrophobicContact CD1-CE1 4.39Å; L87-Y318 HydrophobicContact CD2-CD1 4.42Å; L87-Y318 HydrophobicContact CG-CE1 4.44Å
88	A	97.3	Very high	96.3	Very high	0 Å²	0	22.4 Å²	22.4	0%	0	12%	0.116	C	C	.	.	H	α-helix	trans	-65.8	-33.5	176.6	0	0	0	0	0	113	L49 A52 D84 M85 M86 M92 P93	L49-A88 HydrophobicContact CD1-CB 4.21Å; L49-A88 WeakPolarHBondContact CD1-O 3.49Å; A52-A88 HydrophobicContact CB-CB 4.23Å; D84-A88 WeakPolarHBondContact O-CB 3.04Å; D84-A88 PolarHBondContact O-N 2.96Å; M85-A88 WeakPolarHBondContact O-CB 3.3Å; M85-A88 PolarHBondContact O-N 3.22Å; M86-A88 VanDerWaalsContact C-N 3.33Å; M86-A88 PolarHBondContact O-N 3.46Å; A88-M92 HydrophobicContact CB-CE 4.05Å; A88-M92 HydrophobicContact CB-SD 3.89Å; A88-P93 VanDerWaalsContact O-CD 3.24Å; A88-P93 WeakPolarHBondContact O-CD 3.4Å
89	I	97.3	Very high	96.4	Very high	74 Å²	74	22.3 Å²	22.3	38%	0.379	12%	0.115	S	C	.	.	H	α-helix	trans	-82.4	-44.6	179.7	-67.3	167.6	0	0	0	111.5	L53 M85 M86 L87 P93	L53-I89 HydrophobicContact CD1-CD1 3.94Å; L53-I89 HydrophobicContact CD1-CG1 3.79Å; M85-I89 HydrophobicContact CG-CD1 3.87Å; M85-I89 WeakPolarHBondContact O-CG1 3.36Å; M85-I89 PolarHBondContact O-N 3.22Å; M86-I89 HydrophobicContact CE-CD1 3.97Å; M86-I89 PolarHBondContact O-N 3.48Å; L87-I89 VanDerWaalsContact C-N 3.35Å; I89-P93 WeakPolarHBondContact O-CD 3.41Å; I89-P93 WeakPolarHBondContact O-CG 3.49Å
90	L	97.1	Very high	96.3	Very high	58 Å²	58	26.5 Å²	26.5	30%	0.304	14%	0.135	S	C	.	.	H	α-helix	trans	-94.6	-12.5	-165.4	-61.5	172.7	0	0	0	114.1	M86 F94 L117 F121	M86-L90 HydrophobicContact CB-CD1 4.39Å; M86-L90 VanDerWaalsContact O-CB 3.27Å; M86-L90 WeakPolarHBondContact O-CB 3.36Å; M86-L90 WeakPolarHBondContact O-CG 3.38Å; M86-L90 PolarHBondContact O-N 2.9Å; M86-L90 HydrophobicContact SD-CD1 4.39Å; L90-F94 VanDerWaalsContact O-CD2 3.24Å; L90-F94 WeakPolarHBondContact O-CD2 3.27Å; L90-F94 WeakPolarHBondContact O-CE2 3.46Å; L90-L117 HydrophobicContact CB-CD1 4.26Å; L90-L117 HydrophobicContact CD1-CD1 4.3Å; L90-L117 HydrophobicContact CD1-CD2 4.44Å; L90-F121 HydrophobicContact CB-CE2 4.45Å; L90-F121 HydrophobicContact CD1-CE2 3.7Å; L90-F121 HydrophobicContact CD1-CZ 3.76Å
91	N	96.3	Very high	96.2	Very high	0 Å²	0	28.9 Å²	28.9	0%	0	15%	0.15	C	C	.	.	T	Hydrogen-bonded Turn	trans	-129.7	-48.1	-176.8	-70	-70.1	0	0	0	113.7	L87 P93 F94 A95 S114 F118 Q185	L87-N91 HydrophobicContact CD1-CB 4.03Å; L87-N91 WeakPolarHBondContact O-CB 3.4Å; L87-N91 PolarHBondContact O-N 3.44Å; L87-N91 VanDerWaalsContact O-N 3.14Å; N91-P93 VanDerWaalsContact C-CD 3.44Å; N91-F94 PolarHBondContact O-N 3.46Å; N91-A95 PolarHBondContact O-N 3.21Å; N91-S114 PolarHBondContact OD1-O 3.45Å; N91-S114 VanDerWaalsContact OD1-O 3.04Å; N91-S114 PolarHBondContact OD1-OG 3.42Å; N91-F118 PolarHBondContact ND2-N 3.47Å; N91-Q185 VanDerWaalsContact CG-NE2 3.33Å; N91-Q185 PolarHBondContact OD1-NE2 2.9Å
92	M	96.9	Very high	95.9	Very high	1 Å²	1	30.9 Å²	30.9	1%	0.005	16%	0.162	C	C	.	.	H	α-helix	trans	-56.9	-38.2	-176.1	-65.7	-173.7	-164.2	0	0	114.9	I48 L49 A52 L87 A88 A95 L96 Y318	I48-M92 HydrophobicContact CG2-SD 4.44Å; L49-M92 HydrophobicContact CB-CB 4.46Å; L49-M92 HydrophobicContact CB-SD 4.35Å; L49-M92 HydrophobicContact CD1-CB 3.81Å; L49-M92 HydrophobicContact CD1-SD 4.28Å; A52-M92 HydrophobicContact CB-CE 4.22Å; A52-M92 HydrophobicContact CB-SD 4.48Å; L87-M92 HydrophobicContact CG-CE 4.43Å; L87-M92 PolarHBondContact O-N 2.75Å; A88-M92 HydrophobicContact CB-CE 4.05Å; A88-M92 HydrophobicContact CB-SD 3.89Å; M92-A95 PolarHBondContact O-N 2.89Å; M92-L96 WeakPolarHBondContact O-CB 3.41Å; M92-L96 PolarHBondContact O-N 3.15Å; M92-Y318 HydrophobicContact CB-CE2 4.47Å; M92-Y318 HydrophobicContact CE-CD1 3.82Å; M92-Y318 HydrophobicContact CE-CG 3.89Å; M92-Y318 HydrophobicContact CG-CD1 3.96Å; M92-Y318 HydrophobicContact CG-CD2 3.86Å; M92-Y318 HydrophobicContact CG-CE1 4.02Å; M92-Y318 HydrophobicContact CG-CE2 3.92Å; M92-Y318 HydrophobicContact CG-CG 3.88Å; M92-Y318 HydrophobicContact SD-CG 4.21Å
93	P	97	Very high	95.6	Very high	42 Å²	42	31.2 Å²	31.2	27%	0.273	17%	0.17	S	C	.	.	H	α-helix	trans	-69	-38.2	-179.9	-20.9	35.5	0	0	0	112.1	L49 A88 I89 N91 L96 V97	L49-P93 HydrophobicContact CD1-CG 4.27Å; L49-P93 HydrophobicContact CD2-CG 4.38Å; A88-P93 VanDerWaalsContact O-CD 3.24Å; A88-P93 WeakPolarHBondContact O-CD 3.4Å; I89-P93 WeakPolarHBondContact O-CD 3.41Å; I89-P93 WeakPolarHBondContact O-CG 3.49Å; N91-P93 VanDerWaalsContact C-CD 3.44Å; P93-L96 WeakPolarHBondContact O-CB 3.23Å; P93-L96 PolarHBondContact O-N 2.97Å; P93-V97 WeakPolarHBondContact O-CG2 3.31Å; P93-V97 PolarHBondContact O-N 2.85Å
94	F	96.5	Very high	95.5	Very high	56 Å²	56	32.2 Å²	32.2	25%	0.246	17%	0.174	C	C	.	.	H	α-helix	trans	-70.2	-38.4	177.8	-56.5	-79.6	0	0	0	111.2	L90 N91 L96 V97 T98 W104 F106 F110	L90-F94 VanDerWaalsContact O-CD2 3.24Å; L90-F94 WeakPolarHBondContact O-CD2 3.27Å; L90-F94 WeakPolarHBondContact O-CE2 3.46Å; N91-F94 PolarHBondContact O-N 3.46Å; F94-L96 VanDerWaalsContact C-N 3.33Å; F94-V97 PolarHBondContact O-N 2.73Å; F94-T98 WeakPolarHBondContact O-CB 3.32Å; F94-T98 PolarHBondContact O-N 3.07Å; F94-T98 PolarHBondContact O-OG1 3.45Å; F94-W104 HydrophobicContact CB-CH2 4.23Å; F94-W104 HydrophobicContact CB-CZ3 4.36Å; F94-F106 HydrophobicContact CB-CD2 4.23Å; F94-F106 HydrophobicContact CB-CE2 3.86Å; F94-F106 HydrophobicContact CB-CZ 4.28Å; F94-F106 AromaticContact CD1-CD1 3.83Å; F94-F106 HydrophobicContact CD1-CD1 3.83Å; F94-F106 HydrophobicContact CD1-CD2 4.08Å; F94-F106 AromaticContact CD1-CE1 3.6Å; F94-F106 HydrophobicContact CD1-CE1 3.6Å; F94-F106 AromaticContact CD1-CE2 3.87Å; F94-F106 HydrophobicContact CD1-CE2 3.87Å; F94-F106 HydrophobicContact CD1-CG 4.06Å; F94-F106 AromaticContact CD1-CZ 3.61Å; F94-F106 HydrophobicContact CD1-CZ 3.61Å; F94-F106 HydrophobicContact CE1-CD1 4.23Å; F94-F106 HydrophobicContact CE1-CE1 4.08Å; F94-F106 HydrophobicContact CE1-CZ 4.48Å; F94-F106 HydrophobicContact CG-CE2 4.38Å; F94-F106 HydrophobicContact CG-CZ 4.42Å; F94-F110 HydrophobicContact CB-CE1 4.19Å; F94-F110 HydrophobicContact CD1-CD1 4.42Å; F94-F110 AromaticContact CD1-CE1 3.38Å; F94-F110 HydrophobicContact CD1-CE1 3.38Å; F94-F110 AromaticContact CD1-CZ 3.75Å; F94-F110 HydrophobicContact CD1-CZ 3.75Å; F94-F110 AromaticContact CD2-CE1 3.96Å; F94-F110 HydrophobicContact CD2-CE1 3.96Å; F94-F110 AromaticContact CD2-CZ 3.78Å; F94-F110 HydrophobicContact CD2-CZ 3.78Å; F94-F110 AromaticContact CE1-CE1 3.63Å; F94-F110 HydrophobicContact CE1-CE1 3.63Å; F94-F110 AromaticContact CE1-CZ 3.57Å; F94-F110 HydrophobicContact CE1-CZ 3.57Å; F94-F110 HydrophobicContact CE2-CE1 4.19Å; F94-F110 AromaticContact CE2-CZ 3.6Å; F94-F110 HydrophobicContact CE2-CZ 3.6Å; F94-F110 AromaticContact CG-CE1 3.56Å; F94-F110 HydrophobicContact CG-CE1 3.56Å; F94-F110 AromaticContact CG-CZ 3.86Å; F94-F110 HydrophobicContact CG-CZ 3.86Å; F94-F110 HydrophobicContact CZ-CE1 4.03Å; F94-F110 HydrophobicContact CZ-CE2 4.37Å; F94-F110 AromaticContact CZ-CZ 3.49Å; F94-F110 HydrophobicContact CZ-CZ 3.49Å; F94-F110 VanDerWaalsContact CZ-CZ 3.49Å
95	A	96.1	Very high	95.4	Very high	0 Å²	0	37.1 Å²	37.1	0%	0	20%	0.199	C	C	.	.	H	α-helix	trans	-61.9	-41.9	170.6	0	0	0	0	0	111.8	M45 N91 M92 T98 V99 P184 Q185 L314 Y318	M45-A95 HydrophobicContact CE-CB 4.41Å; M45-A95 HydrophobicContact SD-CB 3.9Å; N91-A95 PolarHBondContact O-N 3.21Å; M92-A95 PolarHBondContact O-N 2.89Å; A95-T98 PolarHBondContact O-N 3.4Å; A95-V99 WeakPolarHBondContact O-CG2 2.96Å; A95-V99 PolarHBondContact O-N 3.29Å; A95-P184 WeakPolarHBondContact CA-O 3.28Å; A95-Q185 HydrophobicContact CB-CB 4.45Å; A95-L314 HydrophobicContact CB-CD2 4.06Å; A95-Y318 HydrophobicContact CB-CE2 3.9Å
96	L	96.9	Very high	95.3	Very high	27 Å²	27	38.7 Å²	38.7	14%	0.141	21%	0.205	C	C	.	.	H	α-helix	trans	-61.6	-47.7	177.1	173.7	61.7	0	0	0	111.6	S42 M45 A46 M92 P93 F94 T98 V99 M100	S42-L96 WeakPolarHBondContact O-CD1 3.33Å; M45-L96 HydrophobicContact CB-CD1 4.17Å; M45-L96 HydrophobicContact CG-CB 4.35Å; M45-L96 WeakPolarHBondContact SD-CA 3.24Å; M45-L96 HydrophobicContact SD-CB 3.83Å; M45-L96 PolarHBondContact SD-N 3.26Å; A46-L96 HydrophobicContact CB-CD2 4.13Å; M92-L96 WeakPolarHBondContact O-CB 3.41Å; M92-L96 PolarHBondContact O-N 3.15Å; P93-L96 WeakPolarHBondContact O-CB 3.23Å; P93-L96 PolarHBondContact O-N 2.97Å; F94-L96 VanDerWaalsContact C-N 3.33Å; L96-T98 VanDerWaalsContact C-N 3.27Å; L96-T98 PolarHBondContact O-N 3.21Å; L96-V99 WeakPolarHBondContact O-CB 3.49Å; L96-V99 PolarHBondContact O-N 3.39Å; L96-M100 HydrophobicContact CD1-CG 4.42Å; L96-M100 HydrophobicContact CD1-SD 4.37Å; L96-M100 HydrophobicContact CG-SD 4.28Å; L96-M100 WeakPolarHBondContact O-CG 3.36Å; L96-M100 PolarHBondContact O-N 3.29Å
97	V	96.6	Very high	95.2	Very high	50 Å²	50	38.5 Å²	38.5	30%	0.303	21%	0.213	S	C	.	.	H	α-helix	trans	-60.7	-39.2	175.7	172.6	0	0	0	0	111.1	P93 F94 M100 T101 I105 F106	P93-V97 WeakPolarHBondContact O-CG2 3.31Å; P93-V97 PolarHBondContact O-N 2.85Å; F94-V97 PolarHBondContact O-N 2.73Å; V97-M100 CarbonylContact O-C 3.54Å; V97-M100 PolarHBondContact O-N 3.23Å; V97-M100 VanDerWaalsContact O-N 3.15Å; V97-T101 HydrophobicContact CG1-CG2 4.16Å; V97-T101 WeakPolarHBondContact O-CB 3.26Å; V97-T101 WeakPolarHBondContact O-CG2 3.45Å; V97-T101 PolarHBondContact O-N 3.31Å; V97-T101 PolarHBondContact O-OG1 2.98Å; V97-I105 HydrophobicContact CG1-CD1 4.09Å; V97-I105 HydrophobicContact CG1-CG1 4.46Å; V97-F106 HydrophobicContact CB-CE2 4.07Å; V97-F106 HydrophobicContact CB-CZ 3.65Å; V97-F106 HydrophobicContact CG1-CE2 4.04Å; V97-F106 HydrophobicContact CG1-CZ 3.54Å; V97-F106 HydrophobicContact CG2-CZ 4.14Å
98	T	95.3	Very high	95	Very high	1 Å²	1	43.2 Å²	43.2	1%	0.006	24%	0.238	C	C	.	.	H	α-helix	trans	-67.8	-34.9	177.6	-53	0	0	0	0	111.9	F94 A95 L96 T102 W104 P184 F307	F94-T98 WeakPolarHBondContact O-CB 3.32Å; F94-T98 PolarHBondContact O-N 3.07Å; F94-T98 PolarHBondContact O-OG1 3.45Å; A95-T98 PolarHBondContact O-N 3.4Å; L96-T98 VanDerWaalsContact C-N 3.27Å; L96-T98 PolarHBondContact O-N 3.21Å; T98-T102 CarbonylContact O-C 3.59Å; T98-T102 WeakPolarHBondContact O-CA 3.45Å; T98-T102 PolarHBondContact O-N 2.86Å; T98-W104 HydrophobicContact CG2-CB 4.36Å; T98-W104 HydrophobicContact CG2-CE3 4.27Å; T98-W104 VanDerWaalsContact OG1-CE3 3.28Å; T98-P184 WeakPolarHBondContact CB-O 3.39Å; T98-P184 WeakPolarHBondContact CG2-O 3.29Å; T98-P184 PolarHBondContact OG1-O 3.05Å; T98-F307 HydrophobicContact CG2-CE2 4.47Å
99	V	94.4	Very high	94.8	Very high	0 Å²	0	48.6 Å²	48.6	0%	0	27%	0.271	C	S	.	.	H	α-helix	trans	-62.3	-43.5	168.9	171.1	0	0	0	0	110.9	Q38 F41 M45 A95 L96 P184 T311	Q38-V99 WeakPolarHBondContact CG-O 3.47Å; F41-V99 HydrophobicContact CB-CG1 3.65Å; M45-V99 HydrophobicContact CE-CG2 3.59Å; M45-V99 HydrophobicContact SD-CG2 4.34Å; A95-V99 WeakPolarHBondContact O-CG2 2.96Å; A95-V99 PolarHBondContact O-N 3.29Å; L96-V99 WeakPolarHBondContact O-CB 3.49Å; L96-V99 PolarHBondContact O-N 3.39Å; V99-P184 HydrophobicContact CG2-CB 3.73Å; V99-P184 HydrophobicContact CG2-CG 3.9Å; V99-T311 HydrophobicContact CG2-CG2 4Å
100	M	93.8	Very high	94.7	Very high	105 Å²	105	48 Å²	48	52%	0.517	27%	0.266	S	S	.	.	H	α-helix	trans	-71.4	-28.5	-178.9	-69	177.1	69.3	0	0	114.1	Q38 S42 L96 V97	Q38-M100 PolarHBondContact NE2-O 3.05Å; S42-M100 VanDerWaalsContact OG-CG 3.32Å; S42-M100 WeakPolarHBondContact OG-CG 3.41Å; L96-M100 HydrophobicContact CD1-CG 4.42Å; L96-M100 HydrophobicContact CD1-SD 4.37Å; L96-M100 HydrophobicContact CG-SD 4.28Å; L96-M100 WeakPolarHBondContact O-CG 3.36Å; L96-M100 PolarHBondContact O-N 3.29Å; V97-M100 CarbonylContact O-C 3.54Å; V97-M100 PolarHBondContact O-N 3.23Å; V97-M100 VanDerWaalsContact O-N 3.15Å
101	T	92.1	Very high	94.7	Very high	50 Å²	50	45.3 Å²	45.3	31%	0.307	25%	0.252	S	S	.	.	H	α-helix	trans	-103.1	-8.3	-178.3	53.8	0	0	0	0	112	V97 T103 I105	V97-T101 HydrophobicContact CG1-CG2 4.16Å; V97-T101 WeakPolarHBondContact O-CB 3.26Å; V97-T101 WeakPolarHBondContact O-CG2 3.45Å; V97-T101 PolarHBondContact O-N 3.31Å; V97-T101 PolarHBondContact O-OG1 2.98Å; T101-T103 PolarHBondContact O-N 3.27Å; T101-T103 PolarHBondContact O-OG1 3.44Å; T101-T103 VanDerWaalsContact O-OG1 3.13Å; T101-T103 PolarHBondContact OG1-O 2.65Å; T101-I105 HydrophobicContact CG2-CD1 4.48Å
102	T	90.2	Very high	94.6	Very high	42 Å²	42	49.4 Å²	49.4	26%	0.258	27%	0.268	S	S	.	.	S	Bend	trans	55.1	7	-171.4	63.7	0	0	0	0	115	L33 T98	L33-T102 HydrophobicContact CB-CG2 4.33Å; T98-T102 CarbonylContact O-C 3.59Å; T98-T102 WeakPolarHBondContact O-CA 3.45Å; T98-T102 PolarHBondContact O-N 2.86Å
103	T	90.6	Very high	94.6	Very high	78 Å²	78	51.9 Å²	51.9	48%	0.479	28%	0.283	S	S	.	.	S	Bend	trans	-142.8	143.2	-173.6	53.4	0	0	0	0	110.4	T101 I105	T101-T103 PolarHBondContact O-N 3.27Å; T101-T103 PolarHBondContact O-OG1 3.44Å; T101-T103 VanDerWaalsContact O-OG1 3.13Å; T101-T103 PolarHBondContact OG1-O 2.65Å; T103-I105 PolarHBondContact O-N 3.31Å
104	W	93.9	Very high	94.5	Very high	20 Å²	20	49.9 Å²	49.9	8%	0.076	27%	0.27	C	S	.	.			trans	-82.7	108.8	177	-179.4	-87.9	0	0	0	110.6	F94 T98 F106 G107 F110 C111 P181	F94-W104 HydrophobicContact CB-CH2 4.23Å; F94-W104 HydrophobicContact CB-CZ3 4.36Å; T98-W104 HydrophobicContact CG2-CB 4.36Å; T98-W104 HydrophobicContact CG2-CE3 4.27Å; T98-W104 VanDerWaalsContact OG1-CE3 3.28Å; W104-F106 HydrophobicContact CD2-CD2 4.07Å; W104-F106 AromaticContact CE2-CD2 3.97Å; W104-F106 HydrophobicContact CE3-CD2 4.17Å; W104-F106 HydrophobicContact CH2-CD2 4.14Å; W104-F106 HydrophobicContact CZ2-CB 3.99Å; W104-F106 HydrophobicContact CZ2-CD2 4.03Å; W104-F106 HydrophobicContact CZ2-CG 4.45Å; W104-F106 HydrophobicContact CZ3-CD2 4.2Å; W104-G107 PolarHBondContact NE1-O 3.26Å; W104-G107 VanDerWaalsContact NE1-O 3.09Å; W104-F110 HydrophobicContact CH2-CD1 4.19Å; W104-F110 HydrophobicContact CH2-CE1 4.17Å; W104-F110 AromaticContact CZ2-CD1 3.62Å; W104-F110 HydrophobicContact CZ2-CD1 3.62Å; W104-F110 HydrophobicContact CZ2-CE1 4.08Å; W104-C111 HydrophobicContact CZ2-CB 4.11Å; W104-P181 HydrophobicContact CB-CG 3.52Å; W104-P181 HydrophobicContact CD2-CG 4.12Å; W104-P181 HydrophobicContact CE3-CG 4.34Å; W104-P181 HydrophobicContact CG-CG 3.78Å
105	I	94.6	Very high	94.5	Very high	106 Å²	106	47.2 Å²	47.2	54%	0.544	26%	0.258	S	S	.	.			trans	-100.4	-3	-173.9	62.3	170.4	0	0	0	114.6	V97 T101 T103 G107	V97-I105 HydrophobicContact CG1-CD1 4.09Å; V97-I105 HydrophobicContact CG1-CG1 4.46Å; T101-I105 HydrophobicContact CG2-CD1 4.48Å; T103-I105 PolarHBondContact O-N 3.31Å; I105-G107 VanDerWaalsContact C-N 3.27Å; I105-G107 PolarHBondContact O-N 2.97Å
106	F	94.8	Very high	94.6	Very high	61 Å²	61	48.6 Å²	48.6	27%	0.268	27%	0.265	S	S	.	.	S	Bend	trans	-84.8	3.8	-172.2	-56.2	-72.9	0	0	0	114.5	F94 V97 W104 F110	F94-F106 HydrophobicContact CB-CD2 4.23Å; F94-F106 HydrophobicContact CB-CE2 3.86Å; F94-F106 HydrophobicContact CB-CZ 4.28Å; F94-F106 AromaticContact CD1-CD1 3.83Å; F94-F106 HydrophobicContact CD1-CD1 3.83Å; F94-F106 HydrophobicContact CD1-CD2 4.08Å; F94-F106 AromaticContact CD1-CE1 3.6Å; F94-F106 HydrophobicContact CD1-CE1 3.6Å; F94-F106 AromaticContact CD1-CE2 3.87Å; F94-F106 HydrophobicContact CD1-CE2 3.87Å; F94-F106 HydrophobicContact CD1-CG 4.06Å; F94-F106 AromaticContact CD1-CZ 3.61Å; F94-F106 HydrophobicContact CD1-CZ 3.61Å; F94-F106 HydrophobicContact CE1-CD1 4.23Å; F94-F106 HydrophobicContact CE1-CE1 4.08Å; F94-F106 HydrophobicContact CE1-CZ 4.48Å; F94-F106 HydrophobicContact CG-CE2 4.38Å; F94-F106 HydrophobicContact CG-CZ 4.42Å; V97-F106 HydrophobicContact CB-CE2 4.07Å; V97-F106 HydrophobicContact CB-CZ 3.65Å; V97-F106 HydrophobicContact CG1-CE2 4.04Å; V97-F106 HydrophobicContact CG1-CZ 3.54Å; V97-F106 HydrophobicContact CG2-CZ 4.14Å; W104-F106 HydrophobicContact CD2-CD2 4.07Å; W104-F106 AromaticContact CE2-CD2 3.97Å; W104-F106 HydrophobicContact CE3-CD2 4.17Å; W104-F106 HydrophobicContact CH2-CD2 4.14Å; W104-F106 HydrophobicContact CZ2-CB 3.99Å; W104-F106 HydrophobicContact CZ2-CD2 4.03Å; W104-F106 HydrophobicContact CZ2-CG 4.45Å; W104-F106 HydrophobicContact CZ3-CD2 4.2Å; F106-F110 HydrophobicContact CB-CB 4.3Å; F106-F110 HydrophobicContact CB-CD1 3.43Å; F106-F110 VanDerWaalsContact CB-CD1 3.43Å; F106-F110 HydrophobicContact CB-CE1 4.18Å; F106-F110 HydrophobicContact CB-CG 4.21Å; F106-F110 HydrophobicContact CG-CD1 4.05Å; F106-F110 HydrophobicContact CG-CE1 4.32Å; F106-F110 WeakPolarHBondContact O-CB 3.28Å
107	G	93.9	Very high	94.6	Very high	35 Å²	35	48.8 Å²	48.8	36%	0.361	27%	0.266	S	S	.	.			trans	79.9	171	179.1	0	0	0	0	0	114.8	W104 I105 C111	W104-G107 PolarHBondContact NE1-O 3.26Å; W104-G107 VanDerWaalsContact NE1-O 3.09Å; I105-G107 VanDerWaalsContact C-N 3.27Å; I105-G107 PolarHBondContact O-N 2.97Å; G107-C111 PolarHBondContact O-N 3.44Å; G107-C111 VanDerWaalsContact O-N 3.14Å
108	N	93.6	Very high	94.6	Very high	101 Å²	101	46.4 Å²	46.4	54%	0.54	25%	0.251	S	S	.	.	H	α-helix	trans	-74.6	-40	-167.5	-59.9	-7.9	0	0	0	112.7	C111 R112 I179	N108-C111 WeakPolarHBondContact O-CB 3.47Å; N108-C111 PolarHBondContact O-N 2.95Å; N108-R112 PolarHBondContact O-N 3.11Å; N108-I179 HydrophobicContact CB-CD1 4.13Å; N108-I179 HydrophobicContact CB-CG2 4.12Å; N108-I179 WeakPolarHBondContact OD1-CG2 3.33Å
109	T	93.6	Very high	94.7	Very high	113 Å²	113	47 Å²	47	69%	0.693	25%	0.254	S	S	*	.	H	α-helix	trans	-64.7	-46.7	179.3	-53	0	0	0	0	110.7	C111 R112 V113	T109-C111 VanDerWaalsContact C-N 3.3Å; T109-C111 PolarHBondContact O-N 2.75Å; T109-R112 PolarHBondContact O-N 3.13Å; T109-V113 WeakPolarHBondContact O-CG2 3.42Å; T109-V113 PolarHBondContact O-N 3.27Å; T109-V113 VanDerWaalsContact O-N 3.1Å
110	F	95.1	Very high	94.8	Very high	62 Å²	62	47.7 Å²	47.7	27%	0.272	26%	0.257	S	S	.	.	H	α-helix	trans	-66.3	-33.6	178.5	-171.1	-106.3	0	0	0	112.1	F94 W104 F106 R112 V113 S114	F94-F110 HydrophobicContact CB-CE1 4.19Å; F94-F110 HydrophobicContact CD1-CD1 4.42Å; F94-F110 AromaticContact CD1-CE1 3.38Å; F94-F110 HydrophobicContact CD1-CE1 3.38Å; F94-F110 AromaticContact CD1-CZ 3.75Å; F94-F110 HydrophobicContact CD1-CZ 3.75Å; F94-F110 AromaticContact CD2-CE1 3.96Å; F94-F110 HydrophobicContact CD2-CE1 3.96Å; F94-F110 AromaticContact CD2-CZ 3.78Å; F94-F110 HydrophobicContact CD2-CZ 3.78Å; F94-F110 AromaticContact CE1-CE1 3.63Å; F94-F110 HydrophobicContact CE1-CE1 3.63Å; F94-F110 AromaticContact CE1-CZ 3.57Å; F94-F110 HydrophobicContact CE1-CZ 3.57Å; F94-F110 HydrophobicContact CE2-CE1 4.19Å; F94-F110 AromaticContact CE2-CZ 3.6Å; F94-F110 HydrophobicContact CE2-CZ 3.6Å; F94-F110 AromaticContact CG-CE1 3.56Å; F94-F110 HydrophobicContact CG-CE1 3.56Å; F94-F110 AromaticContact CG-CZ 3.86Å; F94-F110 HydrophobicContact CG-CZ 3.86Å; F94-F110 HydrophobicContact CZ-CE1 4.03Å; F94-F110 HydrophobicContact CZ-CE2 4.37Å; F94-F110 AromaticContact CZ-CZ 3.49Å; F94-F110 HydrophobicContact CZ-CZ 3.49Å; F94-F110 VanDerWaalsContact CZ-CZ 3.49Å; W104-F110 HydrophobicContact CH2-CD1 4.19Å; W104-F110 HydrophobicContact CH2-CE1 4.17Å; W104-F110 AromaticContact CZ2-CD1 3.62Å; W104-F110 HydrophobicContact CZ2-CD1 3.62Å; W104-F110 HydrophobicContact CZ2-CE1 4.08Å; F106-F110 HydrophobicContact CB-CB 4.3Å; F106-F110 HydrophobicContact CB-CD1 3.43Å; F106-F110 VanDerWaalsContact CB-CD1 3.43Å; F106-F110 HydrophobicContact CB-CE1 4.18Å; F106-F110 HydrophobicContact CB-CG 4.21Å; F106-F110 HydrophobicContact CG-CD1 4.05Å; F106-F110 HydrophobicContact CG-CE1 4.32Å; F106-F110 WeakPolarHBondContact O-CB 3.28Å; F110-R112 VanDerWaalsContact C-N 3.34Å; F110-R112 PolarHBondContact O-N 3.18Å; F110-V113 PolarHBondContact O-N 3.43Å; F110-S114 WeakPolarHBondContact O-CB 3.26Å; F110-S114 PolarHBondContact O-N 3.22Å
111	C	95.8	Very high	95	Very high	1 Å²	1	43.1 Å²	43.1	1%	0.007	23%	0.234	C	C	.	.	H	α-helix	trans	-55.8	-46.7	172	-180	0	0	0	0	112.6	W104 G107 N108 T109 S114 A115 I179 C186	W104-C111 HydrophobicContact CZ2-CB 4.11Å; G107-C111 PolarHBondContact O-N 3.44Å; G107-C111 VanDerWaalsContact O-N 3.14Å; N108-C111 WeakPolarHBondContact O-CB 3.47Å; N108-C111 PolarHBondContact O-N 2.95Å; T109-C111 VanDerWaalsContact C-N 3.3Å; T109-C111 PolarHBondContact O-N 2.75Å; C111-S114 PolarHBondContact O-N 3.24Å; C111-A115 WeakPolarHBondContact O-CB 3.42Å; C111-A115 PolarHBondContact O-N 3.46Å; C111-I179 HydrophobicContact CB-CD1 4.44Å; C111-C186 WeakPolarHBondContact CA-SG 3.05Å; C111-C186 HydrophobicContact CB-CB 4.12Å; C111-C186 WeakPolarHBondContact CB-SG 3.3Å; C111-C186 WeakPolarHBondContact O-CB 3.1Å; C111-C186 WeakPolarHBondContact SG-CB 3.28Å; C111-C186 CovalentContact SG-SG 2.02Å; C111-C186 PolarHBondContact SG-SG 3.49Å
112	R	95.2	Very high	95.1	Very high	87 Å²	87	41.4 Å²	41.4	33%	0.328	22%	0.224	S	C	.	.	H	α-helix	trans	-65	-44.8	178.2	-68.6	179.7	-171.8	-179	3.3	112.3	N108 T109 F110 A115 M116 L170 L177 I179	N108-R112 PolarHBondContact O-N 3.11Å; T109-R112 PolarHBondContact O-N 3.13Å; F110-R112 VanDerWaalsContact C-N 3.34Å; F110-R112 PolarHBondContact O-N 3.18Å; R112-A115 PolarHBondContact O-N 3.46Å; R112-M116 PolarHBondContact O-N 3.49Å; R112-L170 WeakPolarHBondContact CB-O 3.11Å; R112-L177 HydrophobicContact CG-CD1 4.47Å; R112-I179 HydrophobicContact CG-CD1 4.14Å
113	V	96.2	Very high	95.4	Very high	53 Å²	53	39.7 Å²	39.7	32%	0.321	21%	0.213	S	C	.	.	H	α-helix	trans	-64.7	-43.5	177.8	174.2	0	0	0	0	110.8	T109 F110 A115 M116 L117	T109-V113 WeakPolarHBondContact O-CG2 3.42Å; T109-V113 PolarHBondContact O-N 3.27Å; T109-V113 VanDerWaalsContact O-N 3.1Å; F110-V113 PolarHBondContact O-N 3.43Å; V113-A115 PolarHBondContact O-N 3.34Å; V113-M116 WeakPolarHBondContact O-CB 3.34Å; V113-M116 PolarHBondContact O-N 3.45Å; V113-L117 HydrophobicContact CG1-CD1 3.89Å; V113-L117 HydrophobicContact CG1-CG 4.31Å; V113-L117 WeakPolarHBondContact O-CB 3.09Å; V113-L117 VanDerWaalsContact O-CG 3.32Å; V113-L117 WeakPolarHBondContact O-CG 3.26Å; V113-L117 PolarHBondContact O-N 2.82Å
114	S	96.3	Very high	95.7	Very high	0 Å²	0	36 Å²	36	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-60.9	-44.3	175.6	170.6	0	0	0	0	111.7	N91 F110 C111 M116 L117 F118 Q185	N91-S114 PolarHBondContact OD1-O 3.45Å; N91-S114 VanDerWaalsContact OD1-O 3.04Å; N91-S114 PolarHBondContact OD1-OG 3.42Å; F110-S114 WeakPolarHBondContact O-CB 3.26Å; F110-S114 PolarHBondContact O-N 3.22Å; C111-S114 PolarHBondContact O-N 3.24Å; S114-M116 VanDerWaalsContact C-N 3.34Å; S114-M116 PolarHBondContact O-N 3.33Å; S114-L117 PolarHBondContact O-N 3.41Å; S114-F118 WeakPolarHBondContact O-CB 3.43Å; S114-F118 PolarHBondContact O-N 2.98Å; S114-Q185 PolarHBondContact OG-NE2 3.48Å; S114-Q185 VanDerWaalsContact OG-NE2 3.1Å
115	A	96.2	Very high	95.8	Very high	0 Å²	0	35 Å²	35	0%	0	19%	0.187	C	C	.	.	H	α-helix	trans	-59.7	-45	174.9	0	0	0	0	0	111.6	C111 R112 V113 F118 W119 L177 C186	C111-A115 WeakPolarHBondContact O-CB 3.42Å; C111-A115 PolarHBondContact O-N 3.46Å; R112-A115 PolarHBondContact O-N 3.46Å; V113-A115 PolarHBondContact O-N 3.34Å; A115-F118 PolarHBondContact O-N 2.89Å; A115-W119 PolarHBondContact O-N 3.34Å; A115-W119 VanDerWaalsContact O-N 3.08Å; A115-L177 HydrophobicContact CB-CD1 3.61Å; A115-C186 WeakPolarHBondContact CA-O 3.45Å; A115-C186 HydrophobicContact CB-CB 4.08Å; A115-C186 VanDerWaalsContact CB-O 3.3Å; A115-C186 WeakPolarHBondContact CB-O 3.27Å
116	M	97.1	Very high	95.8	Very high	28 Å²	28	30.2 Å²	30.2	14%	0.138	16%	0.163	C	C	.	.	H	α-helix	trans	-60	-48.4	175.5	177.2	-91.5	165.4	0	0	112	R112 V113 S114 F118 W119 L120 S167 L170 A171	R112-M116 PolarHBondContact O-N 3.49Å; V113-M116 WeakPolarHBondContact O-CB 3.34Å; V113-M116 PolarHBondContact O-N 3.45Å; S114-M116 VanDerWaalsContact C-N 3.34Å; S114-M116 PolarHBondContact O-N 3.33Å; M116-F118 VanDerWaalsContact C-N 3.34Å; M116-F118 PolarHBondContact O-N 2.99Å; M116-W119 PolarHBondContact O-N 2.9Å; M116-L120 HydrophobicContact CE-CB 4.19Å; M116-L120 HydrophobicContact CE-CD1 4.41Å; M116-L120 HydrophobicContact CE-CD2 3.86Å; M116-L120 HydrophobicContact CE-CG 4.39Å; M116-L120 VanDerWaalsContact O-CB 3.29Å; M116-L120 WeakPolarHBondContact O-CB 3.45Å; M116-L120 PolarHBondContact O-N 2.95Å; M116-S167 WeakPolarHBondContact CG-O 3.38Å; M116-L170 HydrophobicContact CB-CB 4.03Å; M116-A171 HydrophobicContact CB-CB 3.88Å; M116-A171 HydrophobicContact CG-CB 4Å
117	L	97.7	Very high	95.8	Very high	32 Å²	32	28.4 Å²	28.4	17%	0.168	16%	0.16	C	C	.	.	H	α-helix	trans	-64.2	-39.6	179.7	-71.7	172.6	0	0	0	111.9	L90 V113 S114 L120 F121	L90-L117 HydrophobicContact CB-CD1 4.26Å; L90-L117 HydrophobicContact CD1-CD1 4.3Å; L90-L117 HydrophobicContact CD1-CD2 4.44Å; V113-L117 HydrophobicContact CG1-CD1 3.89Å; V113-L117 HydrophobicContact CG1-CG 4.31Å; V113-L117 WeakPolarHBondContact O-CB 3.09Å; V113-L117 VanDerWaalsContact O-CG 3.32Å; V113-L117 WeakPolarHBondContact O-CG 3.26Å; V113-L117 PolarHBondContact O-N 2.82Å; S114-L117 PolarHBondContact O-N 3.41Å; L117-L120 HydrophobicContact CD2-CD2 4.3Å; L117-L120 PolarHBondContact O-N 2.85Å; L117-F121 HydrophobicContact CB-CE2 4.04Å; L117-F121 HydrophobicContact CD2-CE2 4.04Å; L117-F121 HydrophobicContact CD2-CZ 4.1Å; L117-F121 WeakPolarHBondContact O-CD2 3.45Å; L117-F121 PolarHBondContact O-N 2.95Å
118	F	96.8	Very high	95.9	Very high	0 Å²	0	26.8 Å²	26.8	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-56.9	-55.7	174.2	176.2	-92.6	0	0	0	110.4	L87 N91 S114 A115 M116 L120 F121 V122 Q185 V187 W284 F287 L314 Y318	L87-F118 HydrophobicContact CD1-CD2 3.89Å; L87-F118 HydrophobicContact CD1-CE2 4.49Å; N91-F118 PolarHBondContact ND2-N 3.47Å; S114-F118 WeakPolarHBondContact O-CB 3.43Å; S114-F118 PolarHBondContact O-N 2.98Å; A115-F118 PolarHBondContact O-N 2.89Å; M116-F118 VanDerWaalsContact C-N 3.34Å; M116-F118 PolarHBondContact O-N 2.99Å; F118-L120 VanDerWaalsContact C-N 3.33Å; F118-L120 PolarHBondContact O-N 3.44Å; F118-F121 PolarHBondContact O-N 3.19Å; F118-V122 HydrophobicContact CD1-CG2 4.36Å; F118-V122 HydrophobicContact CE1-CG2 4.18Å; F118-V122 HydrophobicContact CE2-CG2 4.39Å; F118-V122 HydrophobicContact CZ-CG2 4.2Å; F118-V122 WeakPolarHBondContact O-CB 3.39Å; F118-V122 WeakPolarHBondContact O-CG2 3.22Å; F118-V122 PolarHBondContact O-N 3.25Å; F118-V122 VanDerWaalsContact O-N 3.14Å; F118-Q185 HydrophobicContact CD2-CG 4.17Å; F118-V187 HydrophobicContact CE1-CG1 4.44Å; F118-W284 HydrophobicContact CE1-CH2 4.22Å; F118-W284 AromaticContact CZ-CH2 3.84Å; F118-W284 HydrophobicContact CZ-CH2 3.84Å; F118-W284 HydrophobicContact CZ-CZ3 4.47Å; F118-F287 AromaticContact CE1-CE1 3.82Å; F118-F287 HydrophobicContact CE1-CE1 3.82Å; F118-F287 AromaticContact CE1-CZ 3.77Å; F118-F287 HydrophobicContact CE1-CZ 3.77Å; F118-F287 AromaticContact CZ-CE1 3.97Å; F118-F287 HydrophobicContact CZ-CE1 3.97Å; F118-F287 HydrophobicContact CZ-CE2 4.43Å; F118-F287 AromaticContact CZ-CZ 3.74Å; F118-F287 HydrophobicContact CZ-CZ 3.74Å; F118-L314 HydrophobicContact CE2-CD1 3.94Å; F118-L314 HydrophobicContact CZ-CD1 4.31Å; F118-Y318 HydrophobicContact CD2-CE1 4.2Å; F118-Y318 AromaticContact CE2-CE1 3.81Å; F118-Y318 HydrophobicContact CE2-CE1 3.81Å
119	W	96.4	Very high	95.9	Very high	14 Å²	14	22.3 Å²	22.3	5%	0.053	12%	0.118	C	C	.	.	H	α-helix	trans	-65.4	-34.9	-179.6	-74.9	107.2	0	0	0	112.9	A115 M116 V122 I123 L170 F188 M204 F287	A115-W119 PolarHBondContact O-N 3.34Å; A115-W119 VanDerWaalsContact O-N 3.08Å; M116-W119 PolarHBondContact O-N 2.9Å; W119-V122 HydrophobicContact CE3-CG1 4.27Å; W119-V122 HydrophobicContact CZ3-CG1 4.35Å; W119-V122 PolarHBondContact O-N 2.94Å; W119-I123 HydrophobicContact CB-CD1 4.43Å; W119-I123 VanDerWaalsContact O-CB 3.3Å; W119-I123 WeakPolarHBondContact O-CB 3.18Å; W119-I123 WeakPolarHBondContact O-CD1 3.3Å; W119-I123 WeakPolarHBondContact O-CG1 3.5Å; W119-I123 PolarHBondContact O-N 3.36Å; W119-L170 HydrophobicContact CB-CD1 4.12Å; W119-L170 VanDerWaalsContact CD1-CD1 3.45Å; W119-L170 HydrophobicContact CG-CD1 4Å; W119-F188 HydrophobicContact CD2-CE2 4.16Å; W119-F188 AromaticContact CE2-CD2 3.89Å; W119-F188 AromaticContact CE2-CE2 3.3Å; W119-F188 AromaticContact CE2-CZ 3.94Å; W119-F188 HydrophobicContact CH2-CD2 4.36Å; W119-F188 AromaticContact CH2-CE2 4Å; W119-F188 HydrophobicContact CH2-CE2 4Å; W119-F188 AromaticContact CZ2-CD2 3.47Å; W119-F188 HydrophobicContact CZ2-CD2 3.47Å; W119-F188 VanDerWaalsContact CZ2-CD2 3.47Å; W119-F188 AromaticContact CZ2-CE2 3.22Å; W119-F188 HydrophobicContact CZ2-CE2 3.22Å; W119-F188 HydrophobicContact CZ2-CZ 4.28Å; W119-F188 AromaticContact NE1-CD2 3.97Å; W119-F188 AromaticContact NE1-CE2 3.45Å; W119-F188 AromaticContact NE1-CZ 3.7Å; W119-M204 HydrophobicContact CH2-CE 3.47Å; W119-M204 VanDerWaalsContact CH2-CE 3.47Å; W119-M204 HydrophobicContact CH2-SD 4.25Å; W119-M204 HydrophobicContact CZ2-CE 3.97Å; W119-M204 HydrophobicContact CZ3-CE 4.3Å; W119-F287 HydrophobicContact CH2-CD1 4.43Å; W119-F287 AromaticContact CH2-CE1 3.76Å; W119-F287 HydrophobicContact CH2-CE1 3.76Å; W119-F287 AromaticContact CZ2-CE1 3.85Å; W119-F287 HydrophobicContact CZ2-CE1 3.85Å; W119-F287 HydrophobicContact CZ2-CZ 4.5Å
120	L	97.9	Very high	95.9	Very high	13 Å²	13	18.6 Å²	18.6	7%	0.068	9%	0.094	C	C	.	.	H	α-helix	trans	-56	-56.2	176.1	175.2	65.9	0	0	0	112	M116 L117 F118 V122 I123 E124 W160 S167	M116-L120 HydrophobicContact CE-CB 4.19Å; M116-L120 HydrophobicContact CE-CD1 4.41Å; M116-L120 HydrophobicContact CE-CD2 3.86Å; M116-L120 HydrophobicContact CE-CG 4.39Å; M116-L120 VanDerWaalsContact O-CB 3.29Å; M116-L120 WeakPolarHBondContact O-CB 3.45Å; M116-L120 PolarHBondContact O-N 2.95Å; L117-L120 HydrophobicContact CD2-CD2 4.3Å; L117-L120 PolarHBondContact O-N 2.85Å; F118-L120 VanDerWaalsContact C-N 3.33Å; F118-L120 PolarHBondContact O-N 3.44Å; L120-V122 VanDerWaalsContact C-N 3.31Å; L120-V122 PolarHBondContact O-N 2.89Å; L120-I123 PolarHBondContact O-N 3.4Å; L120-E124 VanDerWaalsContact O-CB 3.32Å; L120-E124 WeakPolarHBondContact O-CB 3.41Å; L120-E124 PolarHBondContact O-N 2.63Å; L120-W160 HydrophobicContact CD1-CE3 4.37Å; L120-W160 HydrophobicContact CD1-CZ3 4.35Å; L120-W160 HydrophobicContact CD2-CZ3 4.18Å; L120-W160 HydrophobicContact CG-CZ3 4.22Å; L120-S167 WeakPolarHBondContact CA-OG 3.5Å; L120-S167 PolarHBondContact N-OG 3.47Å
121	F	97.6	Very high	95.9	Very high	10 Å²	10	16.8 Å²	16.8	4%	0.044	9%	0.087	C	C	.	.	H	α-helix	trans	-72.3	-28.8	-176.2	-59	-52.9	0	0	0	112.5	A83 M86 L87 L90 L117 F118 G125 W160	A83-F121 HydrophobicContact CB-CB 4.46Å; A83-F121 HydrophobicContact CB-CD1 4.43Å; M86-F121 HydrophobicContact CB-CD1 3.8Å; M86-F121 HydrophobicContact CB-CD2 4.08Å; M86-F121 HydrophobicContact CB-CE1 3.41Å; M86-F121 VanDerWaalsContact CB-CE1 3.41Å; M86-F121 HydrophobicContact CB-CE2 3.73Å; M86-F121 HydrophobicContact CB-CG 4.15Å; M86-F121 HydrophobicContact CB-CZ 3.39Å; M86-F121 HydrophobicContact CG-CE1 3.94Å; M86-F121 HydrophobicContact CG-CZ 4.11Å; L87-F121 HydrophobicContact CB-CB 4.06Å; L87-F121 HydrophobicContact CB-CD2 4.3Å; L87-F121 HydrophobicContact CB-CG 4.47Å; L87-F121 HydrophobicContact CD1-CB 4.5Å; L90-F121 HydrophobicContact CB-CE2 4.45Å; L90-F121 HydrophobicContact CD1-CE2 3.7Å; L90-F121 HydrophobicContact CD1-CZ 3.76Å; L117-F121 HydrophobicContact CB-CE2 4.04Å; L117-F121 HydrophobicContact CD2-CE2 4.04Å; L117-F121 HydrophobicContact CD2-CZ 4.1Å; L117-F121 WeakPolarHBondContact O-CD2 3.45Å; L117-F121 PolarHBondContact O-N 2.95Å; F118-F121 PolarHBondContact O-N 3.19Å; F121-G125 PolarHBondContact O-N 2.91Å; F121-W160 AromaticContact CD1-CH2 3.95Å; F121-W160 HydrophobicContact CD1-CH2 3.95Å; F121-W160 HydrophobicContact CD1-CZ3 4.3Å; F121-W160 AromaticContact CE1-CH2 3.79Å; F121-W160 HydrophobicContact CE1-CH2 3.79Å; F121-W160 HydrophobicContact CE1-CZ3 4.02Å
122	V	94.8	Very high	95.8	Very high	14 Å²	14	16.9 Å²	16.9	9%	0.085	9%	0.087	C	C	.	.	H	α-helix	trans	-66.9	-50.5	175	164.5	0	0	0	0	111.1	F118 W119 L120 E124 G125 G126 W284	F118-V122 HydrophobicContact CD1-CG2 4.36Å; F118-V122 HydrophobicContact CE1-CG2 4.18Å; F118-V122 HydrophobicContact CE2-CG2 4.39Å; F118-V122 HydrophobicContact CZ-CG2 4.2Å; F118-V122 WeakPolarHBondContact O-CB 3.39Å; F118-V122 WeakPolarHBondContact O-CG2 3.22Å; F118-V122 PolarHBondContact O-N 3.25Å; F118-V122 VanDerWaalsContact O-N 3.14Å; W119-V122 HydrophobicContact CE3-CG1 4.27Å; W119-V122 HydrophobicContact CZ3-CG1 4.35Å; W119-V122 PolarHBondContact O-N 2.94Å; L120-V122 VanDerWaalsContact C-N 3.31Å; L120-V122 PolarHBondContact O-N 2.89Å; V122-E124 VanDerWaalsContact C-N 3.32Å; V122-G125 PolarHBondContact O-N 3.35Å; V122-G126 PolarHBondContact O-N 2.9Å; V122-W284 HydrophobicContact CB-CH2 3.75Å; V122-W284 HydrophobicContact CB-CZ2 3.98Å; V122-W284 HydrophobicContact CB-CZ3 4.43Å; V122-W284 HydrophobicContact CG1-CD2 4.36Å; V122-W284 HydrophobicContact CG1-CE3 4.03Å; V122-W284 HydrophobicContact CG1-CH2 3.12Å; V122-W284 HydrophobicContact CG1-CZ2 3.46Å; V122-W284 VanDerWaalsContact CG1-CZ2 3.46Å; V122-W284 HydrophobicContact CG1-CZ3 3.39Å; V122-W284 HydrophobicContact CG2-CH2 3.19Å; V122-W284 HydrophobicContact CG2-CZ2 3.41Å; V122-W284 VanDerWaalsContact CG2-CZ2 3.41Å; V122-W284 HydrophobicContact CG2-CZ3 4.24Å
123	I	96.3	Very high	95.5	Very high	6 Å²	6	12.9 Å²	12.9	3%	0.031	7%	0.073	C	C	.	.	H	α-helix	trans	-62.2	-44.9	178.4	-68.4	168	0	0	0	109.5	W119 L120 G125 G126 A127 S163 L203 F207	W119-I123 HydrophobicContact CB-CD1 4.43Å; W119-I123 VanDerWaalsContact O-CB 3.3Å; W119-I123 WeakPolarHBondContact O-CB 3.18Å; W119-I123 WeakPolarHBondContact O-CD1 3.3Å; W119-I123 WeakPolarHBondContact O-CG1 3.5Å; W119-I123 PolarHBondContact O-N 3.36Å; L120-I123 PolarHBondContact O-N 3.4Å; I123-G125 PolarHBondContact O-N 3.31Å; I123-G126 PolarHBondContact O-N 3.33Å; I123-A127 WeakPolarHBondContact O-CB 3.39Å; I123-A127 PolarHBondContact O-N 3.5Å; I123-S163 WeakPolarHBondContact CG2-OG 3.14Å; I123-L203 HydrophobicContact CD1-CD2 4.25Å; I123-F207 HydrophobicContact CB-CD1 4.36Å; I123-F207 HydrophobicContact CB-CG 4.43Å; I123-F207 HydrophobicContact CD1-CD2 3.76Å; I123-F207 HydrophobicContact CD1-CE2 3.96Å; I123-F207 HydrophobicContact CD1-CG 4.11Å; I123-F207 HydrophobicContact CD1-CZ 4.45Å; I123-F207 HydrophobicContact CG1-CB 4.06Å; I123-F207 HydrophobicContact CG1-CD1 4.28Å; I123-F207 HydrophobicContact CG1-CD2 4.03Å; I123-F207 HydrophobicContact CG1-CG 3.85Å; I123-F207 HydrophobicContact CG2-CB 4.44Å; I123-F207 HydrophobicContact CG2-CD1 3.27Å; I123-F207 HydrophobicContact CG2-CD2 4.31Å; I123-F207 HydrophobicContact CG2-CE1 3.37Å; I123-F207 HydrophobicContact CG2-CE2 4.4Å; I123-F207 HydrophobicContact CG2-CG 3.75Å; I123-F207 HydrophobicContact CG2-CZ 3.96Å
124	E	97.3	Very high	95.4	Very high	0 Å²	0	13.4 Å²	13.4	0%	0	7%	0.073	C	C	.	.	H	α-helix	trans	-59.7	-47.9	177.4	-176.3	59.5	-160.2	0	0	111.4	N79 A83 L120 V122 G126 A127 I128 T159 W160 S163	N79-E124 PolarHBondContact ND2-OE1 3.48Å; A83-E124 HydrophobicContact CB-CB 4.45Å; A83-E124 HydrophobicContact CB-CG 4.18Å; L120-E124 VanDerWaalsContact O-CB 3.32Å; L120-E124 WeakPolarHBondContact O-CB 3.41Å; L120-E124 PolarHBondContact O-N 2.63Å; V122-E124 VanDerWaalsContact C-N 3.32Å; E124-G126 VanDerWaalsContact C-N 3.34Å; E124-G126 PolarHBondContact O-N 3.35Å; E124-A127 PolarHBondContact O-N 3.47Å; E124-I128 VanDerWaalsContact O-CG1 3.31Å; E124-I128 WeakPolarHBondContact O-CG1 3.21Å; E124-I128 PolarHBondContact O-N 3.13Å; E124-T159 PolarHBondContact OE1-OG1 3.41Å; E124-T159 VanDerWaalsContact OE2-CB 3.25Å; E124-T159 WeakPolarHBondContact OE2-CB 3.38Å; E124-T159 PolarHBondContact OE2-OG1 3Å; E124-T159 VanDerWaalsContact OE2-OG1 3.12Å; E124-W160 HydrophobicContact CG-CD2 4.28Å; E124-W160 HydrophobicContact CG-CH2 4.4Å; E124-W160 HydrophobicContact CG-CZ2 3.95Å; E124-W160 PolarHBondContact OE1-NE1 2.97Å; E124-W160 PolarHBondContact OE2-N 3.33Å; E124-S163 PolarHBondContact N-OG 3.04Å; E124-S163 PolarHBondContact OE2-OG 3.47Å
125	G	94.9	Very high	95.1	Very high	0 Å²	0	14 Å²	14	0%	0	8%	0.076	C	C	.	.	H	α-helix	trans	-61	-40.9	177.7	0	0	0	0	0	113.2	L80 F121 V122 I123 L129	L80-G125 VanDerWaalsContact CD1-CA 3.48Å; L80-G125 WeakPolarHBondContact CD1-O 3.3Å; F121-G125 PolarHBondContact O-N 2.91Å; V122-G125 PolarHBondContact O-N 3.35Å; I123-G125 PolarHBondContact O-N 3.31Å; G125-L129 WeakPolarHBondContact O-CG 3.4Å; G125-L129 PolarHBondContact O-N 2.91Å
126	G	94.1	Very high	94.7	Very high	5 Å²	5	16.2 Å²	16.2	5%	0.052	9%	0.085	C	C	.	.	H	α-helix	trans	-65.9	-43.3	175.6	0	0	0	0	0	112.9	V122 I123 E124 I128 L129 L130	V122-G126 PolarHBondContact O-N 2.9Å; I123-G126 PolarHBondContact O-N 3.33Å; E124-G126 VanDerWaalsContact C-N 3.34Å; E124-G126 PolarHBondContact O-N 3.35Å; G126-I128 VanDerWaalsContact C-N 3.34Å; G126-I128 PolarHBondContact O-N 2.8Å; G126-L129 PolarHBondContact O-N 3.21Å; G126-L130 PolarHBondContact O-N 3.32Å
127	A	96.3	Very high	94.2	Very high	23 Å²	23	15.9 Å²	15.9	19%	0.19	8%	0.083	C	C	.	.	H	α-helix	trans	-62.7	-40.3	179	0	0	0	0	0	112	I123 E124 L130 I131 T159	I123-A127 WeakPolarHBondContact O-CB 3.39Å; I123-A127 PolarHBondContact O-N 3.5Å; E124-A127 PolarHBondContact O-N 3.47Å; A127-L130 WeakPolarHBondContact O-CB 3.35Å; A127-L130 PolarHBondContact O-N 3.39Å; A127-I131 WeakPolarHBondContact O-CG1 3.34Å; A127-I131 PolarHBondContact O-N 3.44Å; A127-T159 HydrophobicContact CB-CG2 3.71Å
128	I	95.4	Very high	93.8	Very high	0 Å²	0	16.3 Å²	16.3	0%	0	9%	0.085	C	C	.	.	H	α-helix	trans	-66	-41.6	176.1	-63.3	-64.8	0	0	0	111.7	L76 N79 L80 E124 G126 L130 I131 I132 I156	L76-I128 HydrophobicContact CB-CG2 4.01Å; L76-I128 HydrophobicContact CD2-CD1 3.91Å; L76-I128 HydrophobicContact CD2-CG2 4.49Å; L76-I128 WeakPolarHBondContact O-CG2 3.25Å; N79-I128 VanDerWaalsContact ND2-CD1 3.27Å; N79-I128 WeakPolarHBondContact ND2-CD1 3.35Å; N79-I128 WeakPolarHBondContact ND2-CG1 3.33Å; L80-I128 HydrophobicContact CB-CG2 3.97Å; E124-I128 VanDerWaalsContact O-CG1 3.31Å; E124-I128 WeakPolarHBondContact O-CG1 3.21Å; E124-I128 PolarHBondContact O-N 3.13Å; G126-I128 VanDerWaalsContact C-N 3.34Å; G126-I128 PolarHBondContact O-N 2.8Å; I128-L130 VanDerWaalsContact C-N 3.31Å; I128-L130 PolarHBondContact O-N 2.84Å; I128-I131 HydrophobicContact CD1-CD1 4.31Å; I128-I131 PolarHBondContact O-N 2.95Å; I128-I132 HydrophobicContact CG2-CD1 3.97Å; I128-I132 HydrophobicContact CG2-CG1 4.45Å; I128-I132 VanDerWaalsContact O-CG1 3.26Å; I128-I132 WeakPolarHBondContact O-CG1 2.89Å; I128-I132 PolarHBondContact O-N 3.29Å; I128-I156 HydrophobicContact CD1-CG1 3.9Å
129	L	92.9	Very high	93.3	Very high	7 Å²	7	18.5 Å²	18.5	4%	0.037	10%	0.096	C	C	.	.	H	α-helix	trans	-62.8	-37.8	174.8	-73.1	172.3	0	0	0	112.3	L80 G125 G126 I132 S133 M215 L276 F280	L80-L129 HydrophobicContact CD2-CD2 3.78Å; L80-L129 HydrophobicContact CD2-CG 4.11Å; G125-L129 WeakPolarHBondContact O-CG 3.4Å; G125-L129 PolarHBondContact O-N 2.91Å; G126-L129 PolarHBondContact O-N 3.21Å; L129-I132 PolarHBondContact O-N 3.46Å; L129-S133 WeakPolarHBondContact O-CB 3.39Å; L129-S133 PolarHBondContact O-N 2.85Å; L129-S133 PolarHBondContact O-OG 2.99Å; L129-M215 HydrophobicContact CB-SD 4.49Å; L129-L276 HydrophobicContact CD2-CB 4.32Å; L129-F280 HydrophobicContact CD1-CB 3.85Å; L129-F280 HydrophobicContact CD1-CD2 3.54Å; L129-F280 HydrophobicContact CD1-CE2 4.36Å; L129-F280 HydrophobicContact CD1-CG 3.86Å
130	L	94.9	Very high	92.5	Very high	35 Å²	35	19 Å²	19	18%	0.183	10%	0.1	C	C	.	.	H	α-helix	trans	-61.6	-48.3	173.2	176.3	64.3	0	0	0	111.4	G126 A127 I128 I132 S133 I134 P211 V214 M215	G126-L130 PolarHBondContact O-N 3.32Å; A127-L130 WeakPolarHBondContact O-CB 3.35Å; A127-L130 PolarHBondContact O-N 3.39Å; I128-L130 VanDerWaalsContact C-N 3.31Å; I128-L130 PolarHBondContact O-N 2.84Å; L130-I132 VanDerWaalsContact C-N 3.32Å; L130-I132 PolarHBondContact O-N 3.03Å; L130-S133 WeakPolarHBondContact O-CB 3.21Å; L130-S133 PolarHBondContact O-N 3.31Å; L130-S133 VanDerWaalsContact O-N 3.11Å; L130-I134 HydrophobicContact CD1-CD1 3.96Å; L130-I134 HydrophobicContact CD1-CG1 4.27Å; L130-I134 HydrophobicContact CG-CD1 3.97Å; L130-I134 WeakPolarHBondContact O-CG1 3.23Å; L130-I134 PolarHBondContact O-N 2.93Å; L130-P211 HydrophobicContact CD1-CB 4.44Å; L130-P211 HydrophobicContact CD2-CB 4.09Å; L130-P211 HydrophobicContact CD2-CG 4.27Å; L130-V214 HydrophobicContact CD1-CB 3.95Å; L130-V214 HydrophobicContact CD1-CG1 3.71Å; L130-M215 HydrophobicContact CD1-CG 3.75Å
131	I	95.1	Very high	91.9	Very high	24 Å²	24	20.6 Å²	20.6	12%	0.123	11%	0.11	C	C	.	.	H	α-helix	trans	-58.3	-45.5	177.5	-68.8	161.7	0	0	0	110.7	L76 A127 I128 S133 I134 D135 L155 T159	L76-I131 HydrophobicContact CD1-CG2 3.71Å; L76-I131 HydrophobicContact CD2-CG2 4.27Å; A127-I131 WeakPolarHBondContact O-CG1 3.34Å; A127-I131 PolarHBondContact O-N 3.44Å; I128-I131 HydrophobicContact CD1-CD1 4.31Å; I128-I131 PolarHBondContact O-N 2.95Å; I131-S133 VanDerWaalsContact C-N 3.29Å; I131-S133 PolarHBondContact O-N 3.46Å; I131-I134 PolarHBondContact O-N 3.36Å; I131-D135 WeakPolarHBondContact O-CB 3.31Å; I131-D135 PolarHBondContact O-N 3.45Å; I131-L155 HydrophobicContact CD1-CB 4.08Å; I131-L155 HydrophobicContact CG2-CD1 3.98Å; I131-T159 HydrophobicContact CD1-CG2 3.76Å
132	I	91.8	Very high	91.2	Very high	3 Å²	3	24.5 Å²	24.5	2%	0.015	13%	0.128	C	C	.	.	H	α-helix	trans	-60.4	-41.5	177.1	-67.7	172.3	0	0	0	110.7	I73 L76 L77 I128 L129 L130 R136 I273	I73-I132 HydrophobicContact CD1-CB 4.26Å; I73-I132 HydrophobicContact CD1-CD1 4.06Å; I73-I132 HydrophobicContact CD1-CG1 3.69Å; I73-I132 HydrophobicContact CD1-CG2 3.78Å; L76-I132 HydrophobicContact CB-CD1 4.19Å; L76-I132 HydrophobicContact CB-CG1 4.16Å; L76-I132 HydrophobicContact CD1-CG1 3.99Å; L77-I132 HydrophobicContact CD2-CD1 3.85Å; I128-I132 HydrophobicContact CG2-CD1 3.97Å; I128-I132 HydrophobicContact CG2-CG1 4.45Å; I128-I132 VanDerWaalsContact O-CG1 3.26Å; I128-I132 WeakPolarHBondContact O-CG1 2.89Å; I128-I132 PolarHBondContact O-N 3.29Å; L129-I132 PolarHBondContact O-N 3.46Å; L130-I132 VanDerWaalsContact C-N 3.32Å; L130-I132 PolarHBondContact O-N 3.03Å; I132-R136 HydrophobicContact CG2-CG 4.44Å; I132-R136 WeakPolarHBondContact O-CB 3.43Å; I132-R136 WeakPolarHBondContact O-CG 3.28Å; I132-R136 PolarHBondContact O-N 2.92Å; I132-R136 VanDerWaalsContact O-N 3.13Å; I132-I273 HydrophobicContact CG2-CG1 4.45Å; I132-I273 HydrophobicContact CG2-CG2 4.36Å
133	S	90.8	Very high	90.7	Very high	4 Å²	4	32.6 Å²	32.6	3%	0.028	16%	0.162	C	C	.	.	H	α-helix	trans	-65.7	-44.4	-179.6	-56.7	0	0	0	0	111.9	L129 L130 I131 R136 F137 F219	L129-S133 WeakPolarHBondContact O-CB 3.39Å; L129-S133 PolarHBondContact O-N 2.85Å; L129-S133 PolarHBondContact O-OG 2.99Å; L130-S133 WeakPolarHBondContact O-CB 3.21Å; L130-S133 PolarHBondContact O-N 3.31Å; L130-S133 VanDerWaalsContact O-N 3.11Å; I131-S133 VanDerWaalsContact C-N 3.29Å; I131-S133 PolarHBondContact O-N 3.46Å; S133-R136 PolarHBondContact O-N 2.86Å; S133-F137 PolarHBondContact O-N 3.49Å; S133-F219 VanDerWaalsContact OG-CZ 3.3Å; S133-F219 WeakPolarHBondContact OG-CZ 3.43Å
134	I	92.6	Very high	90.1	Very high	63 Å²	63	35.8 Å²	35.8	32%	0.323	18%	0.177	S	C	.	.	H	α-helix	trans	-64	-49	176.9	-66.4	168.9	0	0	0	110.8	L130 I131 R136 F137 L138 V214 T218	L130-I134 HydrophobicContact CD1-CD1 3.96Å; L130-I134 HydrophobicContact CD1-CG1 4.27Å; L130-I134 HydrophobicContact CG-CD1 3.97Å; L130-I134 WeakPolarHBondContact O-CG1 3.23Å; L130-I134 PolarHBondContact O-N 2.93Å; I131-I134 PolarHBondContact O-N 3.36Å; I134-R136 PolarHBondContact O-N 3.28Å; I134-F137 WeakPolarHBondContact O-CB 3.37Å; I134-F137 PolarHBondContact O-N 2.89Å; I134-F137 VanDerWaalsContact O-N 3.13Å; I134-L138 HydrophobicContact CG2-CD1 4.09Å; I134-L138 HydrophobicContact CG2-CG 4.28Å; I134-L138 WeakPolarHBondContact O-CG 3.45Å; I134-L138 PolarHBondContact O-N 3.19Å; I134-V214 HydrophobicContact CD1-CG1 4.21Å; I134-V214 HydrophobicContact CG1-CG1 4.17Å; I134-T218 HydrophobicContact CG1-CG2 4.47Å
135	D	90.9	Very high	89.5	Confident	12 Å²	12	41.7 Å²	41.7	6%	0.064	21%	0.209	C	C	.	.	H	α-helix	trans	-51.3	-46.4	176.8	171.3	75.2	0	0	0	111.4	I131 F137 L138 I139 L147	I131-D135 WeakPolarHBondContact O-CB 3.31Å; I131-D135 PolarHBondContact O-N 3.45Å; D135-F137 PolarHBondContact O-N 3.18Å; D135-L138 PolarHBondContact O-N 3.1Å; D135-I139 WeakPolarHBondContact O-CG1 3.37Å; D135-I139 PolarHBondContact O-N 2.94Å; D135-I139 WeakPolarHBondContact OD2-CD1 3.28Å; D135-L147 HydrophobicContact CB-CD2 4.05Å; D135-L147 WeakPolarHBondContact OD1-CB 3.3Å; D135-L147 WeakPolarHBondContact OD1-CD2 3.32Å
136	R	86.9	Confident	89.1	Confident	47 Å²	47	47.2 Å²	47.2	18%	0.177	23%	0.232	C	C	.	.	H	α-helix	trans	-68.1	-38.5	-177.7	-66.5	-73	174.7	-119.1	10.3	112	I132 S133 I134 I140 I222 I273	I132-R136 HydrophobicContact CG2-CG 4.44Å; I132-R136 WeakPolarHBondContact O-CB 3.43Å; I132-R136 WeakPolarHBondContact O-CG 3.28Å; I132-R136 PolarHBondContact O-N 2.92Å; I132-R136 VanDerWaalsContact O-N 3.13Å; S133-R136 PolarHBondContact O-N 2.86Å; I134-R136 PolarHBondContact O-N 3.28Å; R136-I140 HydrophobicContact CB-CD1 4.34Å; R136-I140 VanDerWaalsContact O-CB 3.28Å; R136-I140 WeakPolarHBondContact O-CB 3.33Å; R136-I140 VanDerWaalsContact O-CD1 3.25Å; R136-I140 WeakPolarHBondContact O-CD1 3.45Å; R136-I140 WeakPolarHBondContact O-CG1 3.29Å; R136-I140 PolarHBondContact O-N 3.31Å; R136-I222 HydrophobicContact CB-CD1 4.32Å; R136-I273 HydrophobicContact CB-CD1 4.18Å; R136-I273 HydrophobicContact CG-CD1 3.46Å; R136-I273 VanDerWaalsContact CG-CD1 3.46Å; R136-I273 HydrophobicContact CG-CG1 4.22Å
137	F	87.9	Confident	88.9	Confident	22 Å²	22	48.3 Å²	48.3	10%	0.096	24%	0.237	C	C	.	.	H	α-helix	trans	-62.4	-45	172.6	175.4	-95.9	0	0	0	112.5	S133 I134 D135 I139 I140 V141 Q142 F217 T218 I222	S133-F137 PolarHBondContact O-N 3.49Å; I134-F137 WeakPolarHBondContact O-CB 3.37Å; I134-F137 PolarHBondContact O-N 2.89Å; I134-F137 VanDerWaalsContact O-N 3.13Å; D135-F137 PolarHBondContact O-N 3.18Å; F137-I139 PolarHBondContact O-N 3.34Å; F137-I140 PolarHBondContact O-N 3.28Å; F137-V141 HydrophobicContact CD2-CB 3.93Å; F137-V141 HydrophobicContact CD2-CG1 4.47Å; F137-V141 HydrophobicContact CD2-CG2 3.53Å; F137-V141 HydrophobicContact CE2-CB 3.79Å; F137-V141 HydrophobicContact CE2-CG1 3.83Å; F137-V141 HydrophobicContact CE2-CG2 3.69Å; F137-V141 HydrophobicContact CG-CB 4.46Å; F137-V141 HydrophobicContact CG-CG2 4.32Å; F137-V141 HydrophobicContact CZ-CB 4.2Å; F137-V141 HydrophobicContact CZ-CG1 4.07Å; F137-V141 WeakPolarHBondContact O-CB 3.15Å; F137-V141 PolarHBondContact O-N 3.29Å; F137-Q142 HydrophobicContact CE1-CG 4.1Å; F137-Q142 PolarHBondContact O-N 3.45Å; F137-F217 HydrophobicContact CE1-CE1 4.47Å; F137-F217 HydrophobicContact CE2-CE1 4.29Å; F137-F217 AromaticContact CZ-CE1 3.92Å; F137-F217 HydrophobicContact CZ-CE1 3.92Å; F137-F217 HydrophobicContact CZ-CZ 4.46Å; F137-T218 HydrophobicContact CB-CG2 3.72Å; F137-T218 HydrophobicContact CD1-CG2 4.34Å; F137-T218 HydrophobicContact CD2-CG2 4.24Å; F137-T218 WeakPolarHBondContact CD2-O 3.45Å; F137-T218 HydrophobicContact CG-CG2 3.86Å; F137-I222 HydrophobicContact CB-CD1 4.32Å; F137-I222 HydrophobicContact CB-CG1 4.49Å; F137-I222 HydrophobicContact CD2-CG1 4.41Å
138	L	88.9	Confident	88.8	Confident	41 Å²	41	49.1 Å²	49.1	22%	0.215	24%	0.241	C	C	.	.	H	α-helix	trans	-60.2	-46.4	178.2	-66.3	177.8	0	0	0	111.4	I134 D135 Q142 K143 Q144	I134-L138 HydrophobicContact CG2-CD1 4.09Å; I134-L138 HydrophobicContact CG2-CG 4.28Å; I134-L138 WeakPolarHBondContact O-CG 3.45Å; I134-L138 PolarHBondContact O-N 3.19Å; D135-L138 PolarHBondContact O-N 3.1Å; L138-Q142 CarbonylContact O-C 3.31Å; L138-Q142 VanDerWaalsContact O-C 3.31Å; L138-Q142 WeakPolarHBondContact O-CA 3.35Å; L138-Q142 WeakPolarHBondContact O-CB 3.33Å; L138-Q142 PolarHBondContact O-N 3.11Å; L138-K143 PolarHBondContact O-N 2.85Å; L138-Q144 CarbonylContact C-O 3.28Å; L138-Q144 VanDerWaalsContact C-O 3.28Å; L138-Q144 PolarHBondContact O-N 3.49Å
139	I	85.4	Confident	88.5	Confident	46 Å²	46	51.8 Å²	51.8	24%	0.236	26%	0.259	C	S	.	.	H	α-helix	trans	-67.6	-40	-179.5	-69.4	168.8	0	0	0	111.9	D135 F137 K143 Q144 D145	D135-I139 WeakPolarHBondContact O-CG1 3.37Å; D135-I139 PolarHBondContact O-N 2.94Å; D135-I139 WeakPolarHBondContact OD2-CD1 3.28Å; F137-I139 PolarHBondContact O-N 3.34Å; I139-K143 VanDerWaalsContact O-CA 3.31Å; I139-K143 WeakPolarHBondContact O-CA 3.39Å; I139-Q144 WeakPolarHBondContact CA-O 3.46Å; I139-Q144 WeakPolarHBondContact CG1-O 3.5Å; I139-Q144 PolarHBondContact N-O 3.28Å; I139-D145 HydrophobicContact CG1-CB 4.25Å
140	I	80.4	Confident	88.5	Confident	24 Å²	24	59.1 Å²	59.1	12%	0.123	29%	0.293	C	S	.	.	H	α-helix	trans	-87.4	-51.7	-170.9	-62	163.7	0	0	0	111.6	R136 F137 I222 T225 F270	R136-I140 HydrophobicContact CB-CD1 4.34Å; R136-I140 VanDerWaalsContact O-CB 3.28Å; R136-I140 WeakPolarHBondContact O-CB 3.33Å; R136-I140 VanDerWaalsContact O-CD1 3.25Å; R136-I140 WeakPolarHBondContact O-CD1 3.45Å; R136-I140 WeakPolarHBondContact O-CG1 3.29Å; R136-I140 PolarHBondContact O-N 3.31Å; F137-I140 PolarHBondContact O-N 3.28Å; I140-I222 HydrophobicContact CD1-CD1 4.26Å; I140-I222 HydrophobicContact CD1-CG1 4.17Å; I140-I222 HydrophobicContact CD1-CG2 4.05Å; I140-I222 HydrophobicContact CG2-CG2 4.49Å; I140-T225 HydrophobicContact CG2-CG2 4.4Å; I140-F270 HydrophobicContact CD1-CD1 3.31Å; I140-F270 HydrophobicContact CD1-CD2 4.44Å; I140-F270 HydrophobicContact CD1-CE1 3.16Å; I140-F270 HydrophobicContact CD1-CE2 4.31Å; I140-F270 HydrophobicContact CD1-CG 4Å; I140-F270 HydrophobicContact CD1-CZ 3.7Å; I140-F270 HydrophobicContact CG1-CD1 4.2Å; I140-F270 HydrophobicContact CG1-CE1 3.52Å; I140-F270 HydrophobicContact CG1-CZ 3.69Å
141	V	84.2	Confident	88.5	Confident	46 Å²	46	64.3 Å²	64.3	28%	0.279	31%	0.31	S	S	.	.	T	Hydrogen-bonded Turn	trans	-86.2	-45.6	-171.4	-175.6	0	0	0	0	109.9	F137 I222	F137-V141 HydrophobicContact CD2-CB 3.93Å; F137-V141 HydrophobicContact CD2-CG1 4.47Å; F137-V141 HydrophobicContact CD2-CG2 3.53Å; F137-V141 HydrophobicContact CE2-CB 3.79Å; F137-V141 HydrophobicContact CE2-CG1 3.83Å; F137-V141 HydrophobicContact CE2-CG2 3.69Å; F137-V141 HydrophobicContact CG-CB 4.46Å; F137-V141 HydrophobicContact CG-CG2 4.32Å; F137-V141 HydrophobicContact CZ-CB 4.2Å; F137-V141 HydrophobicContact CZ-CG1 4.07Å; F137-V141 WeakPolarHBondContact O-CB 3.15Å; F137-V141 PolarHBondContact O-N 3.29Å; V141-I222 HydrophobicContact CG2-CG1 4.02Å
142	Q	82.8	Confident	88.5	Confident	92 Å²	92	63.1 Å²	63.1	43%	0.43	30%	0.304	S	S	.	.	S	Bend	trans	-92.7	-9.1	-178.1	-58	-170.2	-10.3	0	0	113.7	F137 L138 Q144	F137-Q142 HydrophobicContact CE1-CG 4.1Å; F137-Q142 PolarHBondContact O-N 3.45Å; L138-Q142 CarbonylContact O-C 3.31Å; L138-Q142 VanDerWaalsContact O-C 3.31Å; L138-Q142 WeakPolarHBondContact O-CA 3.35Å; L138-Q142 WeakPolarHBondContact O-CB 3.33Å; L138-Q142 PolarHBondContact O-N 3.11Å; Q142-Q144 HydrophobicContact CB-CG 4.18Å; Q142-Q144 PolarHBondContact O-N 2.99Å
143	K	84.6	Confident	88.7	Confident	184 Å²	184	69.1 Å²	69.1	80%	0.8	33%	0.33	S	S	*	.			trans	56.7	31.8	-176.2	-54.9	178.4	-176.7	174.9	0	113.4	L138 I139	L138-K143 PolarHBondContact O-N 2.85Å; I139-K143 VanDerWaalsContact O-CA 3.31Å; I139-K143 WeakPolarHBondContact O-CA 3.39Å
144	Q	84.3	Confident	89	Confident	73 Å²	73	74 Å²	74	34%	0.341	36%	0.355	S	S	.	.			trans	-108.4	116.8	179.1	-65.5	-178.2	9.6	0	0	110.1	L138 I139 Q142 K146	L138-Q144 CarbonylContact C-O 3.28Å; L138-Q144 VanDerWaalsContact C-O 3.28Å; L138-Q144 PolarHBondContact O-N 3.49Å; I139-Q144 WeakPolarHBondContact CA-O 3.46Å; I139-Q144 WeakPolarHBondContact CG1-O 3.5Å; I139-Q144 PolarHBondContact N-O 3.28Å; Q142-Q144 HydrophobicContact CB-CG 4.18Å; Q142-Q144 PolarHBondContact O-N 2.99Å; Q144-K146 HydrophobicContact CB-CD 4.48Å; Q144-K146 HydrophobicContact CB-CG 4.46Å
145	D	85.1	Confident	89.2	Confident	125 Å²	125	73.9 Å²	73.9	67%	0.668	36%	0.355	S	S	*	.			trans	-101.9	99.7	170.4	-167.8	-5.5	0	0	0	109.6	I139	I139-D145 HydrophobicContact CG1-CB 4.25Å
146	K	85.9	Confident	89.5	Confident	115 Å²	115	74.2 Å²	74.2	50%	0.5	36%	0.356	S	S	.	.			trans	-114.9	-10.3	-174.1	-73.5	177.5	172.1	171.2	0	113.1	Q144 S148 R151	Q144-K146 HydrophobicContact CB-CD 4.48Å; Q144-K146 HydrophobicContact CB-CG 4.46Å; K146-S148 PolarHBondContact O-N 3.14Å; K146-R151 VanDerWaalsContact O-CD 3.3Å; K146-R151 WeakPolarHBondContact O-CD 3.15Å; K146-R151 PolarHBondContact O-NH1 3.42Å
147	L	90.4	Very high	90	Very high	28 Å²	28	76.2 Å²	76.2	15%	0.147	37%	0.374	C	S	.	.			trans	-90.6	97.6	-170.7	-172.7	71.3	0	0	0	110.8	A72 L76 D135 A152 L155	A72-L147 HydrophobicContact CB-CD2 3.97Å; A72-L147 HydrophobicContact CB-CG 3.86Å; A72-L147 WeakPolarHBondContact CB-O 3.49Å; L76-L147 HydrophobicContact CD1-CD2 3.84Å; D135-L147 HydrophobicContact CB-CD2 4.05Å; D135-L147 WeakPolarHBondContact OD1-CB 3.3Å; D135-L147 WeakPolarHBondContact OD1-CD2 3.32Å; L147-A152 HydrophobicContact CD1-CB 4.29Å; L147-L155 HydrophobicContact CD1-CD1 3.97Å
148	S	92.7	Very high	90.5	Very high	40 Å²	40	79.5 Å²	79.5	28%	0.28	39%	0.391	S	S	.	.			trans	-86.5	158.5	171.3	75.1	0	0	0	0	111.7	K146 Q150 R151 A152	K146-S148 PolarHBondContact O-N 3.14Å; S148-Q150 PolarHBondContact O-N 3.47Å; S148-R151 PolarHBondContact O-N 3.43Å; S148-R151 VanDerWaalsContact O-N 3.14Å; S148-R151 WeakPolarHBondContact OG-CG 3.49Å; S148-R151 PolarHBondContact OG-N 2.99Å; S148-A152 PolarHBondContact O-N 3.45Å
149	P	90.6	Very high	91	Very high	57 Å²	57	78.2 Å²	78.2	37%	0.37	39%	0.385	S	S	.	.	H	α-helix	trans	-56.2	-34.1	174.4	-28.3	36.4	0	0	0	114	A72 I75 K153	A72-P149 HydrophobicContact CB-CG 4.37Å; I75-P149 HydrophobicContact CD1-CB 3.87Å; P149-K153 WeakPolarHBondContact O-CG 3.46Å; P149-K153 PolarHBondContact O-N 3.24Å; P149-K153 VanDerWaalsContact O-N 3.09Å
150	Q	93.2	Very high	91.6	Very high	161 Å²	161	78.6 Å²	78.6	75%	0.752	38%	0.384	S	S	*	.	H	α-helix	trans	-68.1	-45.2	176.2	-69.6	175.3	-22.2	0	0	111.4	S148 A152 K153 L154	S148-Q150 PolarHBondContact O-N 3.47Å; Q150-A152 VanDerWaalsContact C-N 3.33Å; Q150-A152 PolarHBondContact O-N 3.27Å; Q150-K153 PolarHBondContact O-N 2.94Å; Q150-L154 PolarHBondContact O-N 3.34Å
151	R	94.9	Very high	92.4	Very high	143 Å²	143	81.7 Å²	81.7	54%	0.54	40%	0.403	S	S	.	.	H	α-helix	trans	-62.2	-41	174.9	-73.6	178.2	175.8	179	-2.4	111.5	K146 S148 K153 L154 L155	K146-R151 VanDerWaalsContact O-CD 3.3Å; K146-R151 WeakPolarHBondContact O-CD 3.15Å; K146-R151 PolarHBondContact O-NH1 3.42Å; S148-R151 PolarHBondContact O-N 3.43Å; S148-R151 VanDerWaalsContact O-N 3.14Å; S148-R151 WeakPolarHBondContact OG-CG 3.49Å; S148-R151 PolarHBondContact OG-N 2.99Å; R151-K153 PolarHBondContact O-N 3.08Å; R151-L154 PolarHBondContact O-N 2.89Å; R151-L155 VanDerWaalsContact O-CG 3.31Å; R151-L155 WeakPolarHBondContact O-CG 3.29Å; R151-L155 PolarHBondContact O-N 3.26Å
152	A	95.2	Very high	93	Very high	0 Å²	0	83.1 Å²	83.1	0%	0	41%	0.409	C	S	.	.	H	α-helix	trans	-60.1	-44.6	175.5	0	0	0	0	0	112.2	A72 L76 L147 S148 Q150 L154 L155 I156	A72-A152 HydrophobicContact CB-CB 4.07Å; L76-A152 HydrophobicContact CD2-CB 4.3Å; L76-A152 HydrophobicContact CG-CB 4.26Å; L147-A152 HydrophobicContact CD1-CB 4.29Å; S148-A152 PolarHBondContact O-N 3.45Å; Q150-A152 VanDerWaalsContact C-N 3.33Å; Q150-A152 PolarHBondContact O-N 3.27Å; A152-L154 PolarHBondContact O-N 3.21Å; A152-L155 PolarHBondContact O-N 3.43Å; A152-I156 VanDerWaalsContact O-CG1 3.29Å; A152-I156 WeakPolarHBondContact O-CG1 3.41Å; A152-I156 PolarHBondContact O-N 3.09Å
153	K	94.8	Very high	93.7	Very high	128 Å²	128	78.8 Å²	78.8	56%	0.557	39%	0.389	S	S	*	.	H	α-helix	trans	-61.6	-42.7	174.8	-71.6	176	-177.1	-174.8	0	112.4	I75 P149 Q150 R151 I156 V157	I75-K153 HydrophobicContact CG2-CG 4.38Å; P149-K153 WeakPolarHBondContact O-CG 3.46Å; P149-K153 PolarHBondContact O-N 3.24Å; P149-K153 VanDerWaalsContact O-N 3.09Å; Q150-K153 PolarHBondContact O-N 2.94Å; R151-K153 PolarHBondContact O-N 3.08Å; K153-I156 PolarHBondContact O-N 3.34Å; K153-V157 WeakPolarHBondContact O-CG2 3.22Å; K153-V157 PolarHBondContact O-N 3.01Å
154	L	96.7	Very high	94.3	Very high	107 Å²	107	72 Å²	72	56%	0.56	37%	0.365	S	S	*	.	H	α-helix	trans	-61.7	-46.1	175.8	177.3	62.7	0	0	0	111.4	Q150 R151 A152 I156 V157 I158	Q150-L154 PolarHBondContact O-N 3.34Å; R151-L154 PolarHBondContact O-N 2.89Å; A152-L154 PolarHBondContact O-N 3.21Å; L154-I156 VanDerWaalsContact C-N 3.32Å; L154-I156 PolarHBondContact O-N 3.33Å; L154-V157 PolarHBondContact O-N 3.42Å; L154-I158 HydrophobicContact CD1-CD1 4.25Å; L154-I158 HydrophobicContact CD1-CG1 4.49Å; L154-I158 HydrophobicContact CG-CD1 3.99Å; L154-I158 WeakPolarHBondContact O-CG1 3.23Å; L154-I158 PolarHBondContact O-N 3.43Å
155	L	97.3	Very high	94.9	Very high	60 Å²	60	72.8 Å²	72.8	31%	0.314	37%	0.374	S	S	.	.	H	α-helix	trans	-59.8	-42	176.7	-71.6	173.2	0	0	0	111.7	I131 L147 R151 A152 V157 I158 T159	I131-L155 HydrophobicContact CD1-CB 4.08Å; I131-L155 HydrophobicContact CG2-CD1 3.98Å; L147-L155 HydrophobicContact CD1-CD1 3.97Å; R151-L155 VanDerWaalsContact O-CG 3.31Å; R151-L155 WeakPolarHBondContact O-CG 3.29Å; R151-L155 PolarHBondContact O-N 3.26Å; A152-L155 PolarHBondContact O-N 3.43Å; L155-V157 PolarHBondContact O-N 3.31Å; L155-I158 PolarHBondContact O-N 2.9Å; L155-T159 WeakPolarHBondContact O-CG2 2.95Å; L155-T159 PolarHBondContact O-N 3.32Å; L155-T159 PolarHBondContact O-OG1 2.93Å
156	I	97.9	Very high	95.4	Very high	19 Å²	19	69.6 Å²	69.6	10%	0.097	36%	0.355	C	S	.	.	H	α-helix	trans	-57.6	-48.8	174.1	-72	163.5	0	0	0	110.7	I75 L76 N79 I128 A152 K153 L154 I158 T159 W160	I75-I156 HydrophobicContact CG2-CD1 3.68Å; L76-I156 HydrophobicContact CD2-CD1 4.07Å; L76-I156 HydrophobicContact CD2-CG1 3.91Å; N79-I156 HydrophobicContact CB-CD1 3.84Å; N79-I156 HydrophobicContact CB-CG1 4.17Å; N79-I156 HydrophobicContact CB-CG2 4.5Å; N79-I156 WeakPolarHBondContact OD1-CG2 3.49Å; I128-I156 HydrophobicContact CD1-CG1 3.9Å; A152-I156 VanDerWaalsContact O-CG1 3.29Å; A152-I156 WeakPolarHBondContact O-CG1 3.41Å; A152-I156 PolarHBondContact O-N 3.09Å; K153-I156 PolarHBondContact O-N 3.34Å; L154-I156 VanDerWaalsContact C-N 3.32Å; L154-I156 PolarHBondContact O-N 3.33Å; I156-I158 VanDerWaalsContact C-N 3.28Å; I156-I158 PolarHBondContact O-N 2.75Å; I156-T159 WeakPolarHBondContact CA-OG1 3.49Å; I156-T159 PolarHBondContact O-N 3.28Å; I156-T159 PolarHBondContact O-OG1 3.39Å; I156-W160 VanDerWaalsContact CG2-CD1 3.47Å; I156-W160 PolarHBondContact O-N 3.39Å
157	V	97.9	Very high	95.8	Very high	90 Å²	90	64.1 Å²	64.1	55%	0.545	33%	0.331	S	S	.	.	H	α-helix	trans	-59.4	-42.4	178.4	173.4	0	0	0	0	111.1	K153 L154 L155 W160 V161	K153-V157 WeakPolarHBondContact O-CG2 3.22Å; K153-V157 PolarHBondContact O-N 3.01Å; L154-V157 PolarHBondContact O-N 3.42Å; L155-V157 PolarHBondContact O-N 3.31Å; V157-W160 PolarHBondContact O-N 2.86Å; V157-V161 WeakPolarHBondContact O-CG2 3.49Å; V157-V161 PolarHBondContact O-N 3.18Å; V157-V161 VanDerWaalsContact O-N 3.07Å
158	I	98	Very high	96.1	Very high	90 Å²	90	65.3 Å²	65.3	46%	0.462	34%	0.341	S	S	.	.	H	α-helix	trans	-62.1	-45.8	177.2	-67.2	165.9	0	0	0	111	L154 L155 I156 V161 L162	L154-I158 HydrophobicContact CD1-CD1 4.25Å; L154-I158 HydrophobicContact CD1-CG1 4.49Å; L154-I158 HydrophobicContact CG-CD1 3.99Å; L154-I158 WeakPolarHBondContact O-CG1 3.23Å; L154-I158 PolarHBondContact O-N 3.43Å; L155-I158 PolarHBondContact O-N 2.9Å; I156-I158 VanDerWaalsContact C-N 3.28Å; I156-I158 PolarHBondContact O-N 2.75Å; I158-V161 PolarHBondContact O-N 3.21Å; I158-L162 WeakPolarHBondContact O-CB 3.36Å; I158-L162 PolarHBondContact O-N 3.27Å
159	T	98	Very high	96.2	Very high	14 Å²	14	65.2 Å²	65.2	9%	0.086	34%	0.34	C	S	.	.	H	α-helix	trans	-65.5	-40.9	179.5	55.4	0	0	0	0	111.5	E124 A127 I131 L155 I156 V161 L162 S163	E124-T159 PolarHBondContact OE1-OG1 3.41Å; E124-T159 VanDerWaalsContact OE2-CB 3.25Å; E124-T159 WeakPolarHBondContact OE2-CB 3.38Å; E124-T159 PolarHBondContact OE2-OG1 3Å; E124-T159 VanDerWaalsContact OE2-OG1 3.12Å; A127-T159 HydrophobicContact CB-CG2 3.71Å; I131-T159 HydrophobicContact CD1-CG2 3.76Å; L155-T159 WeakPolarHBondContact O-CG2 2.95Å; L155-T159 PolarHBondContact O-N 3.32Å; L155-T159 PolarHBondContact O-OG1 2.93Å; I156-T159 WeakPolarHBondContact CA-OG1 3.49Å; I156-T159 PolarHBondContact O-N 3.28Å; I156-T159 PolarHBondContact O-OG1 3.39Å; T159-V161 PolarHBondContact O-N 2.88Å; T159-L162 PolarHBondContact O-N 3.38Å; T159-S163 VanDerWaalsContact O-CB 3.28Å; T159-S163 WeakPolarHBondContact O-CB 3.34Å; T159-S163 PolarHBondContact O-N 3.05Å; T159-S163 PolarHBondContact O-OG 3.45Å
160	W	98.1	Very high	96.3	Very high	55 Å²	55	62.5 Å²	62.5	21%	0.208	32%	0.322	C	S	.	.	H	α-helix	trans	-59.9	-45.1	175.5	-86.5	102.9	0	0	0	112.7	N79 F82 L120 F121 E124 I156 V157 S164	N79-W160 PolarHBondContact OD1-NE1 2.86Å; F82-W160 HydrophobicContact CD1-CH2 4.32Å; F82-W160 AromaticContact CD1-CZ2 3.84Å; F82-W160 HydrophobicContact CD1-CZ2 3.84Å; F82-W160 HydrophobicContact CE1-CH2 4.04Å; F82-W160 AromaticContact CE1-CZ2 3.87Å; F82-W160 HydrophobicContact CE1-CZ2 3.87Å; L120-W160 HydrophobicContact CD1-CE3 4.37Å; L120-W160 HydrophobicContact CD1-CZ3 4.35Å; L120-W160 HydrophobicContact CD2-CZ3 4.18Å; L120-W160 HydrophobicContact CG-CZ3 4.22Å; F121-W160 AromaticContact CD1-CH2 3.95Å; F121-W160 HydrophobicContact CD1-CH2 3.95Å; F121-W160 HydrophobicContact CD1-CZ3 4.3Å; F121-W160 AromaticContact CE1-CH2 3.79Å; F121-W160 HydrophobicContact CE1-CH2 3.79Å; F121-W160 HydrophobicContact CE1-CZ3 4.02Å; E124-W160 HydrophobicContact CG-CD2 4.28Å; E124-W160 HydrophobicContact CG-CH2 4.4Å; E124-W160 HydrophobicContact CG-CZ2 3.95Å; E124-W160 PolarHBondContact OE1-NE1 2.97Å; E124-W160 PolarHBondContact OE2-N 3.33Å; I156-W160 VanDerWaalsContact CG2-CD1 3.47Å; I156-W160 PolarHBondContact O-N 3.39Å; V157-W160 PolarHBondContact O-N 2.86Å; W160-S164 VanDerWaalsContact O-CB 3.26Å; W160-S164 WeakPolarHBondContact O-CB 3.45Å; W160-S164 PolarHBondContact O-N 3.47Å; W160-S164 PolarHBondContact O-OG 3.05Å
161	V	98.1	Very high	96.3	Very high	88 Å²	88	56.7 Å²	56.7	53%	0.533	30%	0.302	S	S	.	.	H	α-helix	trans	-61.8	-48.1	177.1	171.2	0	0	0	0	110	V157 I158 T159 S164 V165	V157-V161 WeakPolarHBondContact O-CG2 3.49Å; V157-V161 PolarHBondContact O-N 3.18Å; V157-V161 VanDerWaalsContact O-N 3.07Å; I158-V161 PolarHBondContact O-N 3.21Å; T159-V161 PolarHBondContact O-N 2.88Å; V161-S164 PolarHBondContact O-N 3.24Å; V161-V165 HydrophobicContact CG1-CG2 4.42Å; V161-V165 VanDerWaalsContact O-CG2 3.28Å; V161-V165 WeakPolarHBondContact O-CG2 3.3Å; V161-V165 PolarHBondContact O-N 3.24Å
162	L	96.9	Very high	96.2	Very high	76 Å²	76	55.3 Å²	55.3	40%	0.398	31%	0.309	S	S	.	.	H	α-helix	trans	-62.1	-49.5	179.9	-171	66.2	0	0	0	111.9	I158 T159 S164 V165 F166 F207	I158-L162 WeakPolarHBondContact O-CB 3.36Å; I158-L162 PolarHBondContact O-N 3.27Å; T159-L162 PolarHBondContact O-N 3.38Å; L162-S164 VanDerWaalsContact C-N 3.25Å; L162-S164 PolarHBondContact O-N 3.49Å; L162-V165 PolarHBondContact O-N 3.22Å; L162-F166 HydrophobicContact CD1-CD2 3.73Å; L162-F166 HydrophobicContact CD1-CE2 3.44Å; L162-F166 VanDerWaalsContact CD1-CE2 3.44Å; L162-F166 HydrophobicContact CG-CD2 4.12Å; L162-F166 HydrophobicContact CG-CE2 4.22Å; L162-F166 WeakPolarHBondContact O-CD2 3.32Å; L162-F166 PolarHBondContact O-N 2.86Å; L162-F207 HydrophobicContact CD2-CE1 4.17Å; L162-F207 HydrophobicContact CG-CE1 4.33Å; L162-F207 HydrophobicContact CG-CZ 4.31Å
163	S	97.7	Very high	95.8	Very high	1 Å²	1	55.8 Å²	55.8	1%	0.007	31%	0.314	C	S	.	.	H	α-helix	trans	-57.8	-40.1	177.8	-56.1	0	0	0	0	111.3	I123 E124 T159 S167	I123-S163 WeakPolarHBondContact CG2-OG 3.14Å; E124-S163 PolarHBondContact N-OG 3.04Å; E124-S163 PolarHBondContact OE2-OG 3.47Å; T159-S163 VanDerWaalsContact O-CB 3.28Å; T159-S163 WeakPolarHBondContact O-CB 3.34Å; T159-S163 PolarHBondContact O-N 3.05Å; T159-S163 PolarHBondContact O-OG 3.45Å; S163-S167 VanDerWaalsContact O-CB 3.23Å; S163-S167 WeakPolarHBondContact O-CB 3Å; S163-S167 PolarHBondContact O-N 3.49Å; S163-S167 PolarHBondContact O-OG 3.4Å
164	S	96.8	Very high	95.4	Very high	43 Å²	43	53.6 Å²	53.6	30%	0.301	32%	0.315	S	S	.	.	H	α-helix	trans	-67.4	-47.4	177.9	-59	0	0	0	0	112.1	W160 V161 L162 F166 S167 S168	W160-S164 VanDerWaalsContact O-CB 3.26Å; W160-S164 WeakPolarHBondContact O-CB 3.45Å; W160-S164 PolarHBondContact O-N 3.47Å; W160-S164 PolarHBondContact O-OG 3.05Å; V161-S164 PolarHBondContact O-N 3.24Å; L162-S164 VanDerWaalsContact C-N 3.25Å; L162-S164 PolarHBondContact O-N 3.49Å; S164-F166 VanDerWaalsContact C-N 3.31Å; S164-F166 PolarHBondContact O-N 2.86Å; S164-S167 PolarHBondContact O-N 3.5Å; S164-S168 VanDerWaalsContact O-CB 3.24Å; S164-S168 WeakPolarHBondContact O-CB 3.42Å; S164-S168 PolarHBondContact O-N 2.87Å; S164-S168 PolarHBondContact O-OG 3.08Å
165	V	96.4	Very high	94.9	Very high	88 Å²	88	49 Å²	49	53%	0.533	29%	0.291	S	S	.	.	H	α-helix	trans	-59.8	-42	179.5	167.1	0	0	0	0	111.6	V161 L162 S168 P169	V161-V165 HydrophobicContact CG1-CG2 4.42Å; V161-V165 VanDerWaalsContact O-CG2 3.28Å; V161-V165 WeakPolarHBondContact O-CG2 3.3Å; V161-V165 PolarHBondContact O-N 3.24Å; L162-V165 PolarHBondContact O-N 3.22Å; V165-S168 PolarHBondContact O-OG 3.14Å; V165-P169 WeakPolarHBondContact O-CD 3.46Å
166	F	95.4	Very high	94.4	Very high	58 Å²	58	56.3 Å²	56.3	25%	0.254	32%	0.315	S	S	.	.	H	α-helix	trans	-77.5	-28.9	-178.8	-84.9	-90.7	0	0	0	113.4	L162 S164 P169 Y199 I202 L203 F207	L162-F166 HydrophobicContact CD1-CD2 3.73Å; L162-F166 HydrophobicContact CD1-CE2 3.44Å; L162-F166 VanDerWaalsContact CD1-CE2 3.44Å; L162-F166 HydrophobicContact CG-CD2 4.12Å; L162-F166 HydrophobicContact CG-CE2 4.22Å; L162-F166 WeakPolarHBondContact O-CD2 3.32Å; L162-F166 PolarHBondContact O-N 2.86Å; S164-F166 VanDerWaalsContact C-N 3.31Å; S164-F166 PolarHBondContact O-N 2.86Å; F166-P169 WeakPolarHBondContact O-CD 3.31Å; F166-Y199 PolarHBondContact O-OH 3.36Å; F166-I202 HydrophobicContact CE1-CG2 4.14Å; F166-L203 HydrophobicContact CB-CD2 3.94Å; F166-L203 HydrophobicContact CD1-CD2 3.94Å; F166-L203 HydrophobicContact CG-CD2 4.4Å; F166-F207 HydrophobicContact CB-CE2 3.6Å; F166-F207 HydrophobicContact CB-CZ 3.82Å; F166-F207 AromaticContact CD1-CE2 3.58Å; F166-F207 HydrophobicContact CD1-CE2 3.58Å; F166-F207 HydrophobicContact CD1-CZ 4.04Å; F166-F207 HydrophobicContact CD2-CE2 4.01Å; F166-F207 AromaticContact CD2-CZ 3.6Å; F166-F207 HydrophobicContact CD2-CZ 3.6Å; F166-F207 HydrophobicContact CE1-CE2 4.2Å; F166-F207 HydrophobicContact CE1-CZ 4.5Å; F166-F207 HydrophobicContact CE2-CZ 4.13Å; F166-F207 AromaticContact CG-CE2 3.44Å; F166-F207 HydrophobicContact CG-CE2 3.44Å; F166-F207 VanDerWaalsContact CG-CE2 3.44Å; F166-F207 AromaticContact CG-CZ 3.53Å; F166-F207 HydrophobicContact CG-CZ 3.53Å
167	S	95.9	Very high	94	Very high	1 Å²	1	56.2 Å²	56.2	1%	0.007	32%	0.315	C	S	.	.	H	α-helix	trans	-89.9	-28.2	-178.5	-51.6	0	0	0	0	113.4	M116 L120 S163 S164 L170	M116-S167 WeakPolarHBondContact CG-O 3.38Å; L120-S167 WeakPolarHBondContact CA-OG 3.5Å; L120-S167 PolarHBondContact N-OG 3.47Å; S163-S167 VanDerWaalsContact O-CB 3.23Å; S163-S167 WeakPolarHBondContact O-CB 3Å; S163-S167 PolarHBondContact O-N 3.49Å; S163-S167 PolarHBondContact O-OG 3.4Å; S164-S167 PolarHBondContact O-N 3.5Å; S167-L170 WeakPolarHBondContact O-CB 3.49Å; S167-L170 PolarHBondContact O-N 3.34Å
168	S	95.2	Very high	93.4	Very high	52 Å²	52	56 Å²	56	36%	0.364	31%	0.308	S	S	.	.	H	α-helix	trans	-56.4	-33.2	-177.5	63.6	0	0	0	0	116	S164 V165 L170 A171 V172	S164-S168 VanDerWaalsContact O-CB 3.24Å; S164-S168 WeakPolarHBondContact O-CB 3.42Å; S164-S168 PolarHBondContact O-N 2.87Å; S164-S168 PolarHBondContact O-OG 3.08Å; V165-S168 PolarHBondContact O-OG 3.14Å; S168-L170 PolarHBondContact O-N 3.41Å; S168-L170 VanDerWaalsContact O-N 3.15Å; S168-A171 WeakPolarHBondContact O-CB 3.19Å; S168-A171 PolarHBondContact O-N 2.92Å; S168-V172 PolarHBondContact O-N 3.39Å
169	P	95	Very high	92.8	Very high	38 Å²	38	53.8 Å²	53.8	25%	0.247	30%	0.296	C	S	.	.	H	α-helix	trans	-57.9	-30.7	179.2	-24.6	36.1	0	0	0	113.2	V165 F166 A171 V172 G173 S174 Y199	V165-P169 WeakPolarHBondContact O-CD 3.46Å; F166-P169 WeakPolarHBondContact O-CD 3.31Å; P169-A171 VanDerWaalsContact C-N 3.34Å; P169-A171 PolarHBondContact O-N 3.46Å; P169-V172 PolarHBondContact O-N 2.65Å; P169-G173 PolarHBondContact O-N 3.22Å; P169-S174 CarbonylContact C-O 3.58Å; P169-S174 VanDerWaalsContact C-O 3.25Å; P169-S174 WeakPolarHBondContact CB-O 3.32Å; P169-S174 CarbonylContact O-C 3.34Å; P169-S174 PolarHBondContact O-N 3.18Å; P169-Y199 HydrophobicContact CB-CE2 4.22Å; P169-Y199 HydrophobicContact CG-CE2 4.17Å
170	L	92.8	Very high	92.1	Very high	0 Å²	0	57.7 Å²	57.7	0%	0	32%	0.322	C	S	.	.	H	α-helix	trans	-61.1	-39.4	175	-68.8	162.3	0	0	0	112.8	R112 M116 W119 S167 S168 G173 L177 F188 Y199	R112-L170 WeakPolarHBondContact CB-O 3.11Å; M116-L170 HydrophobicContact CB-CB 4.03Å; W119-L170 HydrophobicContact CB-CD1 4.12Å; W119-L170 VanDerWaalsContact CD1-CD1 3.45Å; W119-L170 HydrophobicContact CG-CD1 4Å; S167-L170 WeakPolarHBondContact O-CB 3.49Å; S167-L170 PolarHBondContact O-N 3.34Å; S168-L170 PolarHBondContact O-N 3.41Å; S168-L170 VanDerWaalsContact O-N 3.15Å; L170-G173 PolarHBondContact O-N 2.73Å; L170-L177 HydrophobicContact CD2-CD1 4.08Å; L170-L177 HydrophobicContact CD2-CD2 3.99Å; L170-L177 HydrophobicContact CD2-CG 4.2Å; L170-F188 HydrophobicContact CD2-CE1 3.79Å; L170-F188 HydrophobicContact CD2-CZ 4.37Å; L170-Y199 HydrophobicContact CD2-CE1 4.13Å; L170-Y199 HydrophobicContact CG-CE1 4.19Å
171	A	93.6	Very high	91.6	Very high	39 Å²	39	56 Å²	56	32%	0.322	32%	0.318	S	S	.	.	H	α-helix	trans	-69	-37.8	178.9	0	0	0	0	0	111.6	M116 S168 P169 G173	M116-A171 HydrophobicContact CB-CB 3.88Å; M116-A171 HydrophobicContact CG-CB 4Å; S168-A171 WeakPolarHBondContact O-CB 3.19Å; S168-A171 PolarHBondContact O-N 2.92Å; P169-A171 VanDerWaalsContact C-N 3.34Å; P169-A171 PolarHBondContact O-N 3.46Å; A171-G173 PolarHBondContact O-N 2.94Å
172	V	91.9	Very high	91.2	Very high	114 Å²	114	56.4 Å²	56.4	69%	0.691	31%	0.31	S	S	*	.	H	α-helix	trans	-69.1	-23.5	175.8	-176.6	0	0	0	0	111.2	S168 P169	S168-V172 PolarHBondContact O-N 3.39Å; P169-V172 PolarHBondContact O-N 2.65Å
173	G	86.6	Confident	91	Very high	11 Å²	11	53 Å²	53	11%	0.113	29%	0.293	C	S	.	.	T	Hydrogen-bonded Turn	trans	88.6	23.2	-178.3	0	0	0	0	0	113.4	P169 L170 A171 P175 R176	P169-G173 PolarHBondContact O-N 3.22Å; L170-G173 PolarHBondContact O-N 2.73Å; A171-G173 PolarHBondContact O-N 2.94Å; G173-P175 CarbonylContact C-O 3.25Å; G173-P175 CarbonylContact O-C 3.35Å; G173-R176 PolarHBondContact O-N 2.97Å
174	S	87.5	Confident	90.8	Very high	81 Å²	81	53 Å²	53	57%	0.566	29%	0.293	S	S	*	.	S	Bend	trans	-122.8	102.2	172.3	-176.9	0	0	0	0	108.8	P169	P169-S174 CarbonylContact C-O 3.58Å; P169-S174 VanDerWaalsContact C-O 3.25Å; P169-S174 WeakPolarHBondContact CB-O 3.32Å; P169-S174 CarbonylContact O-C 3.34Å; P169-S174 PolarHBondContact O-N 3.18Å
175	P	86.8	Confident	90.7	Very high	11 Å²	11	51 Å²	51	7%	0.071	28%	0.279	C	S	.	.	S	Bend	cis	-84.8	164	14.1	38	-39.9	0	0	0	112.9	G173 L177 Y196 Y199	G173-P175 CarbonylContact C-O 3.25Å; G173-P175 CarbonylContact O-C 3.35Å; P175-L177 PolarHBondContact O-N 3.13Å; P175-Y196 HydrophobicContact CB-CD2 3.56Å; P175-Y196 HydrophobicContact CB-CE2 4.41Å; P175-Y196 HydrophobicContact CB-CG 4.07Å; P175-Y196 HydrophobicContact CG-CD2 3.74Å; P175-Y196 HydrophobicContact CG-CE2 4.19Å; P175-Y196 HydrophobicContact CG-CG 4.26Å; P175-Y199 HydrophobicContact CG-CD1 3.56Å; P175-Y199 HydrophobicContact CG-CE1 4.1Å; P175-Y199 HydrophobicContact CG-CG 4.04Å
176	R	86.8	Confident	90.5	Very high	214 Å²	214	46.9 Å²	46.9	81%	0.808	25%	0.254	S	S	*	.			trans	-69.8	115.4	-177.7	-65.6	-174.8	-176.3	-153.6	1.8	110.4	G173 Y196	G173-R176 PolarHBondContact O-N 2.97Å; R176-Y196 WeakPolarHBondContact O-CE2 3.36Å
177	L	87.9	Confident	90.4	Very high	17 Å²	17	44.9 Å²	44.9	9%	0.089	25%	0.246	C	C	.	.			trans	-74.5	148.5	170.6	-70.1	170.2	0	0	0	111	R112 A115 L170 P175 I179 F188	R112-L177 HydrophobicContact CG-CD1 4.47Å; A115-L177 HydrophobicContact CB-CD1 3.61Å; L170-L177 HydrophobicContact CD2-CD1 4.08Å; L170-L177 HydrophobicContact CD2-CD2 3.99Å; L170-L177 HydrophobicContact CD2-CG 4.2Å; P175-L177 PolarHBondContact O-N 3.13Å; L177-I179 HydrophobicContact CB-CG1 4.41Å; L177-I179 PolarHBondContact O-N 2.99Å; L177-F188 HydrophobicContact CD2-CD1 4.29Å
178	Q	86.3	Confident	90.3	Very high	85 Å²	85	44.9 Å²	44.9	40%	0.397	25%	0.246	S	C	.	.			trans	-73	119.1	171.2	-69.2	-68.8	-2.4	0	0	109.6	Y190 Y301	Q178-Y190 WeakPolarHBondContact CG-O 3.22Å; Q178-Y190 PolarHBondContact NE2-O 3.26Å; Q178-Y301 VanDerWaalsContact CB-OH 3.29Å; Q178-Y301 WeakPolarHBondContact CB-OH 3.43Å; Q178-Y301 HydrophobicContact CG-CE1 4.33Å
179	I	85.6	Confident	90.2	Very high	43 Å²	43	42.5 Å²	42.5	22%	0.221	23%	0.229	C	C	.	.	S	Bend	trans	-132	128.2	-178	-52.7	174.8	0	0	0	108.4	N108 C111 R112 L177	N108-I179 HydrophobicContact CB-CD1 4.13Å; N108-I179 HydrophobicContact CB-CG2 4.12Å; N108-I179 WeakPolarHBondContact OD1-CG2 3.33Å; C111-I179 HydrophobicContact CB-CD1 4.44Å; R112-I179 HydrophobicContact CG-CD1 4.14Å; L177-I179 HydrophobicContact CB-CG1 4.41Å; L177-I179 PolarHBondContact O-N 2.99Å
180	P	82.1	Confident	90.1	Very high	96 Å²	96	43.4 Å²	43.4	62%	0.623	23%	0.228	S	C	*	.	S	Bend	cis	-67.2	147.4	-0.5	27.9	-34.3	0	0	0	112.9
181	P	88.5	Confident	90.1	Very high	19 Å²	19	44.4 Å²	44.4	12%	0.123	24%	0.235	C	C	.	.			trans	-65.3	141.7	175.9	31.5	-39.3	0	0	0	110.5	W104 A183	W104-P181 HydrophobicContact CB-CG 3.52Å; W104-P181 HydrophobicContact CD2-CG 4.12Å; W104-P181 HydrophobicContact CE3-CG 4.34Å; W104-P181 HydrophobicContact CG-CG 3.78Å; P181-A183 PolarHBondContact O-N 2.74Å
182	R	90.5	Very high	90	Very high	98 Å²	98	46.1 Å²	46.1	37%	0.37	25%	0.25	S	C	.	.	S	Bend	trans	-84.7	9.6	170.3	-63.5	178.5	68.4	85.8	-0.6	112.9	Y301 F306 F307	R182-Y301 HydrophobicContact CB-CE2 4.25Å; R182-Y301 HydrophobicContact CG-CE1 4.31Å; R182-Y301 PolarHBondContact NE-O 3.01Å; R182-F306 HydrophobicContact CB-CD1 3.61Å; R182-F306 HydrophobicContact CB-CE1 3.64Å; R182-F306 VanDerWaalsContact O-CD1 3.26Å; R182-F306 WeakPolarHBondContact O-CD1 3.22Å; R182-F306 WeakPolarHBondContact O-CE1 3.12Å; R182-F307 WeakPolarHBondContact O-CD2 3.33Å
183	A	92.5	Very high	90.1	Very high	5 Å²	5	44.6 Å²	44.6	4%	0.041	24%	0.237	C	C	.	.	S	Bend	trans	-125.8	158.5	-178	0	0	0	0	0	110	P181 Q185 V187 F306	P181-A183 PolarHBondContact O-N 2.74Å; A183-Q185 PolarHBondContact O-N 3.27Å; A183-Q185 VanDerWaalsContact O-N 3.13Å; A183-V187 HydrophobicContact CB-CG2 4.09Å; A183-F306 HydrophobicContact CB-CE1 4.31Å
184	P	92.7	Very high	90.4	Very high	1 Å²	1	48.7 Å²	48.7	1%	0.006	26%	0.262	C	S	.	.	S	Bend	trans	-61.5	-21.5	179	-22.8	31.8	0	0	0	114.7	A95 T98 V99 F307 T311 L314	A95-P184 WeakPolarHBondContact CA-O 3.28Å; T98-P184 WeakPolarHBondContact CB-O 3.39Å; T98-P184 WeakPolarHBondContact CG2-O 3.29Å; T98-P184 PolarHBondContact OG1-O 3.05Å; V99-P184 HydrophobicContact CG2-CB 3.73Å; V99-P184 HydrophobicContact CG2-CG 3.9Å; P184-F307 HydrophobicContact CB-CZ 4.43Å; P184-F307 HydrophobicContact CG-CE1 4.3Å; P184-F307 HydrophobicContact CG-CE2 3.99Å; P184-F307 HydrophobicContact CG-CZ 3.84Å; P184-T311 HydrophobicContact CG-CG2 4.3Å; P184-T311 WeakPolarHBondContact CG-OG1 3.38Å; P184-L314 HydrophobicContact CB-CD2 4.02Å
185	Q	94.2	Very high	90.6	Very high	1 Å²	1	46.8 Å²	46.8	1%	0.005	26%	0.255	C	S	.	.	S	Bend	trans	-124.8	144.2	179.5	177.5	68.6	-5	0	0	108.4	N91 A95 S114 F118 A183 V187 L314	N91-Q185 VanDerWaalsContact CG-NE2 3.33Å; N91-Q185 PolarHBondContact OD1-NE2 2.9Å; A95-Q185 HydrophobicContact CB-CB 4.45Å; S114-Q185 PolarHBondContact OG-NE2 3.48Å; S114-Q185 VanDerWaalsContact OG-NE2 3.1Å; F118-Q185 HydrophobicContact CD2-CG 4.17Å; A183-Q185 PolarHBondContact O-N 3.27Å; A183-Q185 VanDerWaalsContact O-N 3.13Å; Q185-V187 HydrophobicContact CB-CG1 4.15Å; Q185-V187 HydrophobicContact CG-CG1 3.87Å; Q185-V187 PolarHBondContact O-N 3.14Å; Q185-L314 HydrophobicContact CB-CD1 4.01Å; Q185-L314 HydrophobicContact CB-CD2 3.62Å; Q185-L314 HydrophobicContact CB-CG 4.48Å; Q185-L314 HydrophobicContact CG-CD1 4.32Å
186	C	93.7	Very high	91	Very high	1 Å²	1	46.3 Å²	46.3	1%	0.007	25%	0.252	C	S	.	.			trans	-66.8	107.1	171.5	-72.1	0	0	0	0	110.3	C111 A115	C111-C186 WeakPolarHBondContact CA-SG 3.05Å; C111-C186 HydrophobicContact CB-CB 4.12Å; C111-C186 WeakPolarHBondContact CB-SG 3.3Å; C111-C186 WeakPolarHBondContact O-CB 3.1Å; C111-C186 WeakPolarHBondContact SG-CB 3.28Å; C111-C186 CovalentContact SG-SG 2.02Å; C111-C186 PolarHBondContact SG-SG 3.49Å; A115-C186 WeakPolarHBondContact CA-O 3.45Å; A115-C186 HydrophobicContact CB-CB 4.08Å; A115-C186 VanDerWaalsContact CB-O 3.3Å; A115-C186 WeakPolarHBondContact CB-O 3.27Å
187	V	92.4	Very high	91.4	Very high	15 Å²	15	38 Å²	38	9%	0.091	22%	0.222	C	C	.	.			trans	-135.9	-179.6	-178.3	-61	0	0	0	0	109.7	F118 A183 Q185 G189 F287 Y290	F118-V187 HydrophobicContact CE1-CG1 4.44Å; A183-V187 HydrophobicContact CB-CG2 4.09Å; Q185-V187 HydrophobicContact CB-CG1 4.15Å; Q185-V187 HydrophobicContact CG-CG1 3.87Å; Q185-V187 PolarHBondContact O-N 3.14Å; V187-G189 PolarHBondContact O-N 3.33Å; V187-F287 HydrophobicContact CB-CZ 4.38Å; V187-F287 HydrophobicContact CG1-CE2 4.43Å; V187-F287 HydrophobicContact CG1-CZ 3.93Å; V187-Y290 HydrophobicContact CG2-CE1 4.48Å
188	F	94	Very high	91.7	Very high	1 Å²	1	39.4 Å²	39.4	0%	0.004	24%	0.237	C	C	.	.			trans	-61	128.1	177.8	-62.8	-55.9	0	0	0	111.6	W119 L170 L177 Y196 Y199 V200 L203 M204 T294	W119-F188 HydrophobicContact CD2-CE2 4.16Å; W119-F188 AromaticContact CE2-CD2 3.89Å; W119-F188 AromaticContact CE2-CE2 3.3Å; W119-F188 AromaticContact CE2-CZ 3.94Å; W119-F188 HydrophobicContact CH2-CD2 4.36Å; W119-F188 AromaticContact CH2-CE2 4Å; W119-F188 HydrophobicContact CH2-CE2 4Å; W119-F188 AromaticContact CZ2-CD2 3.47Å; W119-F188 HydrophobicContact CZ2-CD2 3.47Å; W119-F188 VanDerWaalsContact CZ2-CD2 3.47Å; W119-F188 AromaticContact CZ2-CE2 3.22Å; W119-F188 HydrophobicContact CZ2-CE2 3.22Å; W119-F188 HydrophobicContact CZ2-CZ 4.28Å; W119-F188 AromaticContact NE1-CD2 3.97Å; W119-F188 AromaticContact NE1-CE2 3.45Å; W119-F188 AromaticContact NE1-CZ 3.7Å; L170-F188 HydrophobicContact CD2-CE1 3.79Å; L170-F188 HydrophobicContact CD2-CZ 4.37Å; L177-F188 HydrophobicContact CD2-CD1 4.29Å; F188-Y196 WeakPolarHBondContact CA-OH 3.48Å; F188-Y196 WeakPolarHBondContact CB-OH 3.42Å; F188-Y196 HydrophobicContact CD1-CE1 4.48Å; F188-Y196 AromaticContact CD1-CZ 3.93Å; F188-Y196 WeakPolarHBondContact CD1-OH 3.41Å; F188-Y199 HydrophobicContact CE1-CD1 4.12Å; F188-Y199 AromaticContact CE1-CE1 3.88Å; F188-Y199 HydrophobicContact CE1-CE1 3.88Å; F188-Y199 HydrophobicContact CZ-CD1 4.37Å; F188-Y199 AromaticContact CZ-CE1 3.96Å; F188-Y199 HydrophobicContact CZ-CE1 3.96Å; F188-V200 HydrophobicContact CB-CG2 4.42Å; F188-V200 HydrophobicContact CD1-CG2 3.61Å; F188-V200 HydrophobicContact CD2-CG1 4.31Å; F188-V200 HydrophobicContact CD2-CG2 4.13Å; F188-V200 HydrophobicContact CE1-CG2 3.81Å; F188-V200 HydrophobicContact CE2-CG2 4.31Å; F188-V200 HydrophobicContact CG-CG2 3.8Å; F188-V200 HydrophobicContact CZ-CG2 4.2Å; F188-L203 HydrophobicContact CE2-CD1 4.12Å; F188-L203 HydrophobicContact CZ-CD1 3.51Å; F188-M204 HydrophobicContact CD2-CE 3.86Å; F188-M204 HydrophobicContact CE2-CE 3.91Å; F188-T294 WeakPolarHBondContact O-CG2 3.47Å
189	G	92.1	Very high	92.2	Very high	2 Å²	2	37.1 Å²	37.1	2%	0.021	22%	0.224	C	C	.	.			trans	-106.2	-177.4	170.8	0	0	0	0	0	112.4	V187 Y196	V187-G189 PolarHBondContact O-N 3.33Å; G189-Y196 PolarHBondContact N-OH 3.49Å; G189-Y196 WeakPolarHBondContact O-CE1 3.41Å; G189-Y196 PolarHBondContact O-OH 3.33Å
190	Y	93.4	Very high	92.6	Very high	58 Å²	58	35 Å²	35	23%	0.227	21%	0.214	C	C	.	.			trans	-65.8	136.7	171.3	172.7	-99.2	0	0	0	111.4	Q178 T294 F298	Q178-Y190 WeakPolarHBondContact CG-O 3.22Å; Q178-Y190 PolarHBondContact NE2-O 3.26Å; Y190-T294 VanDerWaalsContact CA-O 3.24Å; Y190-T294 WeakPolarHBondContact CA-O 3.41Å; Y190-T294 WeakPolarHBondContact CB-O 3.41Å; Y190-T294 PolarHBondContact N-O 3.45Å; Y190-F298 AromaticContact CD1-CD2 3.8Å; Y190-F298 HydrophobicContact CD1-CD2 3.8Å; Y190-F298 HydrophobicContact CD2-CB 4.1Å; Y190-F298 HydrophobicContact CE1-CB 4.21Å; Y190-F298 AromaticContact CE1-CD2 3.54Å; Y190-F298 HydrophobicContact CE1-CD2 3.54Å; Y190-F298 HydrophobicContact CE1-CE2 4.44Å; Y190-F298 HydrophobicContact CE1-CG 4.36Å; Y190-F298 HydrophobicContact CE2-CB 3.73Å; Y190-F298 HydrophobicContact CG-CB 4.47Å; Y190-F298 HydrophobicContact CG-CD2 4.43Å; Y190-F298 AromaticContact CZ-CD2 3.95Å
191	S	92.9	Very high	93.3	Very high	20 Å²	20	34.5 Å²	34.5	14%	0.14	21%	0.205	C	C	.	.			trans	-142.2	151.8	170.8	-173.3	0	0	0	0	109.6	D193 H197	S191-D193 WeakPolarHBondContact OG-CB 3.31Å; S191-D193 PolarHBondContact OG-N 2.9Å; S191-H197 PolarHBondContact O-CE1 2.95Å; S191-H197 PolarHBondContact O-NE2 3.39Å
192	A	91.6	Very high	93.6	Very high	76 Å²	76	37.8 Å²	37.8	63%	0.628	22%	0.221	S	C	*	.			trans	-98.3	-5.7	169.4	0	0	0	0	0	112.3	P194	A192-P194 WeakPolarHBondContact O-CD 3.42Å
193	D	93.4	Very high	93.9	Very high	81 Å²	81	33.3 Å²	33.3	43%	0.433	20%	0.204	S	C	.	.			trans	-73.4	122	-178	173.1	41.8	0	0	0	111.4	S191 G195 Y196 H197	S191-D193 WeakPolarHBondContact OG-CB 3.31Å; S191-D193 PolarHBondContact OG-N 2.9Å; D193-G195 PolarHBondContact O-N 2.99Å; D193-G195 PolarHBondContact OD1-N 3.23Å; D193-Y196 WeakPolarHBondContact O-CB 3.34Å; D193-Y196 PolarHBondContact O-N 3.36Å; D193-Y196 PolarHBondContact OD2-N 3.41Å; D193-H197 PolarHBondContact O-N 3.44Å; D193-H197 VanDerWaalsContact O-N 3.14Å
194	P	93.1	Very high	94	Very high	97 Å²	97	33.2 Å²	33.2	63%	0.63	20%	0.203	S	C	*	.	H	α-helix	trans	-60	-32.2	176.7	-23.7	34.1	0	0	0	113.2	A192 H197 A198	A192-P194 WeakPolarHBondContact O-CD 3.42Å; P194-H197 PolarHBondContact O-N 2.89Å; P194-A198 WeakPolarHBondContact O-CB 3.27Å; P194-A198 PolarHBondContact O-N 3.39Å
195	G	92.9	Very high	94.2	Very high	41 Å²	41	37.5 Å²	37.5	42%	0.423	23%	0.225	S	C	.	.	H	α-helix	trans	-64.3	-45.4	177	0	0	0	0	0	112.2	D193 H197 A198 Y199	D193-G195 PolarHBondContact O-N 2.99Å; D193-G195 PolarHBondContact OD1-N 3.23Å; G195-H197 PolarHBondContact O-N 3.38Å; G195-A198 PolarHBondContact O-N 3.28Å; G195-Y199 WeakPolarHBondContact O-CB 3.24Å; G195-Y199 PolarHBondContact O-N 3.02Å
196	Y	94.3	Very high	94.2	Very high	1 Å²	1	39.9 Å²	39.9	0%	0.004	24%	0.24	C	C	.	.	H	α-helix	trans	-56.6	-47.5	171.5	-174	-73.5	0	0	0	111.7	P175 R176 F188 G189 D193 Y199 V200 T295	P175-Y196 HydrophobicContact CB-CD2 3.56Å; P175-Y196 HydrophobicContact CB-CE2 4.41Å; P175-Y196 HydrophobicContact CB-CG 4.07Å; P175-Y196 HydrophobicContact CG-CD2 3.74Å; P175-Y196 HydrophobicContact CG-CE2 4.19Å; P175-Y196 HydrophobicContact CG-CG 4.26Å; R176-Y196 WeakPolarHBondContact O-CE2 3.36Å; F188-Y196 WeakPolarHBondContact CA-OH 3.48Å; F188-Y196 WeakPolarHBondContact CB-OH 3.42Å; F188-Y196 HydrophobicContact CD1-CE1 4.48Å; F188-Y196 AromaticContact CD1-CZ 3.93Å; F188-Y196 WeakPolarHBondContact CD1-OH 3.41Å; G189-Y196 PolarHBondContact N-OH 3.49Å; G189-Y196 WeakPolarHBondContact O-CE1 3.41Å; G189-Y196 PolarHBondContact O-OH 3.33Å; D193-Y196 WeakPolarHBondContact O-CB 3.34Å; D193-Y196 PolarHBondContact O-N 3.36Å; D193-Y196 PolarHBondContact OD2-N 3.41Å; Y196-Y199 PolarHBondContact O-N 2.93Å; Y196-V200 HydrophobicContact CD1-CG2 3.91Å; Y196-V200 HydrophobicContact CE1-CG2 3.58Å; Y196-V200 WeakPolarHBondContact O-CG2 3.18Å; Y196-V200 PolarHBondContact O-N 2.93Å; Y196-T295 HydrophobicContact CD1-CG2 3.92Å; Y196-T295 HydrophobicContact CE1-CG2 3.72Å
197	H	94.9	Very high	94.3	Very high	40 Å²	40	41.4 Å²	41.4	19%	0.185	25%	0.246	C	C	.	.	H	α-helix	trans	-61.3	-46.1	178.9	-68.9	174.5	0	0	0	112.1	S191 D193 P194 G195 Y199 V200 L201 T295 F296	S191-H197 PolarHBondContact O-CE1 2.95Å; S191-H197 PolarHBondContact O-NE2 3.39Å; D193-H197 PolarHBondContact O-N 3.44Å; D193-H197 VanDerWaalsContact O-N 3.14Å; P194-H197 PolarHBondContact O-N 2.89Å; G195-H197 PolarHBondContact O-N 3.38Å; H197-Y199 VanDerWaalsContact C-N 3.33Å; H197-Y199 PolarHBondContact O-N 3.47Å; H197-V200 PolarHBondContact O-N 3.1Å; H197-L201 WeakPolarHBondContact O-CB 3.24Å; H197-L201 VanDerWaalsContact O-CG 3.31Å; H197-L201 WeakPolarHBondContact O-CG 3.45Å; H197-L201 PolarHBondContact O-N 3.43Å; H197-T295 VanDerWaalsContact CD2-CG2 3.47Å; H197-T295 WeakPolarHBondContact CD2-CG2 3.32Å; H197-T295 PolarHBondContact NE2-O 3.48Å; H197-F296 HydrophobicContact CB-CE1 3.84Å; H197-F296 HydrophobicContact CB-CZ 4.08Å; H197-F296 AromaticContact CD2-CE1 3.96Å; H197-F296 AromaticContact CE1-CD1 3.89Å; H197-F296 AromaticContact CE1-CE1 3.94Å; H197-F296 AromaticContact CG-CE1 3.51Å; H197-F296 AromaticContact ND1-CD1 3.91Å; H197-F296 AromaticContact ND1-CE1 3.5Å
198	A	95.1	Very high	94.4	Very high	47 Å²	47	41.5 Å²	41.5	39%	0.388	25%	0.245	S	C	.	.	H	α-helix	trans	-59.4	-44.7	177.4	0	0	0	0	0	111.3	P194 G195 L201 I202	P194-A198 WeakPolarHBondContact O-CB 3.27Å; P194-A198 PolarHBondContact O-N 3.39Å; G195-A198 PolarHBondContact O-N 3.28Å; A198-L201 PolarHBondContact O-N 2.92Å; A198-I202 WeakPolarHBondContact O-CB 3.48Å; A198-I202 WeakPolarHBondContact O-CD1 3.42Å; A198-I202 WeakPolarHBondContact O-CG1 3.46Å; A198-I202 PolarHBondContact O-N 3.03Å
199	Y	95.3	Very high	94.4	Very high	36 Å²	36	45.3 Å²	45.3	14%	0.141	26%	0.262	C	S	.	.	H	α-helix	trans	-60.1	-48.8	177.5	178.9	-102.8	0	0	0	112.4	F166 P169 L170 P175 F188 G195 Y196 H197 L201 I202 L203	F166-Y199 PolarHBondContact O-OH 3.36Å; P169-Y199 HydrophobicContact CB-CE2 4.22Å; P169-Y199 HydrophobicContact CG-CE2 4.17Å; L170-Y199 HydrophobicContact CD2-CE1 4.13Å; L170-Y199 HydrophobicContact CG-CE1 4.19Å; P175-Y199 HydrophobicContact CG-CD1 3.56Å; P175-Y199 HydrophobicContact CG-CE1 4.1Å; P175-Y199 HydrophobicContact CG-CG 4.04Å; F188-Y199 HydrophobicContact CE1-CD1 4.12Å; F188-Y199 AromaticContact CE1-CE1 3.88Å; F188-Y199 HydrophobicContact CE1-CE1 3.88Å; F188-Y199 HydrophobicContact CZ-CD1 4.37Å; F188-Y199 AromaticContact CZ-CE1 3.96Å; F188-Y199 HydrophobicContact CZ-CE1 3.96Å; G195-Y199 WeakPolarHBondContact O-CB 3.24Å; G195-Y199 PolarHBondContact O-N 3.02Å; Y196-Y199 PolarHBondContact O-N 2.93Å; H197-Y199 VanDerWaalsContact C-N 3.33Å; H197-Y199 PolarHBondContact O-N 3.47Å; Y199-L201 PolarHBondContact O-N 2.82Å; Y199-I202 PolarHBondContact O-N 3.44Å; Y199-L203 HydrophobicContact CD1-CD1 3.87Å; Y199-L203 HydrophobicContact CE1-CD1 3.29Å; Y199-L203 HydrophobicContact CE1-CG 4.26Å; Y199-L203 HydrophobicContact CE2-CD1 4.11Å; Y199-L203 HydrophobicContact CE2-CG 4.32Å; Y199-L203 VanDerWaalsContact CZ-CD1 3.42Å; Y199-L203 WeakPolarHBondContact O-CG 3.37Å; Y199-L203 PolarHBondContact O-N 3.44Å
200	V	95.6	Very high	94.6	Very high	0 Å²	0	49.1 Å²	49.1	0%	0	28%	0.281	C	S	.	.	H	α-helix	trans	-61.5	-46	177.6	174.7	0	0	0	0	110.9	F188 Y196 H197 I202 L203 M204 L292 T295	F188-V200 HydrophobicContact CB-CG2 4.42Å; F188-V200 HydrophobicContact CD1-CG2 3.61Å; F188-V200 HydrophobicContact CD2-CG1 4.31Å; F188-V200 HydrophobicContact CD2-CG2 4.13Å; F188-V200 HydrophobicContact CE1-CG2 3.81Å; F188-V200 HydrophobicContact CE2-CG2 4.31Å; F188-V200 HydrophobicContact CG-CG2 3.8Å; F188-V200 HydrophobicContact CZ-CG2 4.2Å; Y196-V200 HydrophobicContact CD1-CG2 3.91Å; Y196-V200 HydrophobicContact CE1-CG2 3.58Å; Y196-V200 WeakPolarHBondContact O-CG2 3.18Å; Y196-V200 PolarHBondContact O-N 2.93Å; H197-V200 PolarHBondContact O-N 3.1Å; V200-I202 PolarHBondContact O-N 3.28Å; V200-L203 PolarHBondContact O-N 3.07Å; V200-M204 HydrophobicContact CG1-CE 4.15Å; V200-M204 HydrophobicContact CG1-CG 4.22Å; V200-M204 VanDerWaalsContact O-CG 3.22Å; V200-M204 WeakPolarHBondContact O-CG 3.38Å; V200-M204 PolarHBondContact O-N 3.39Å; V200-L292 HydrophobicContact CG1-CD2 4.44Å; V200-T295 HydrophobicContact CB-CG2 4.3Å; V200-T295 HydrophobicContact CG1-CG2 4.34Å; V200-T295 HydrophobicContact CG2-CG2 4.24Å
201	L	96.3	Very high	94.7	Very high	85 Å²	85	46.7 Å²	46.7	45%	0.445	27%	0.273	S	S	.	.	H	α-helix	trans	-62	-44.2	179.3	-73.7	173.5	0	0	0	112.3	H197 A198 Y199 M204 L205 L292 F296	H197-L201 WeakPolarHBondContact O-CB 3.24Å; H197-L201 VanDerWaalsContact O-CG 3.31Å; H197-L201 WeakPolarHBondContact O-CG 3.45Å; H197-L201 PolarHBondContact O-N 3.43Å; A198-L201 PolarHBondContact O-N 2.92Å; Y199-L201 PolarHBondContact O-N 2.82Å; L201-M204 PolarHBondContact O-N 3.02Å; L201-L205 WeakPolarHBondContact O-CB 3.39Å; L201-L205 PolarHBondContact O-N 3.15Å; L201-L292 HydrophobicContact CD2-CD2 3.85Å; L201-F296 HydrophobicContact CD1-CZ 3.88Å; L201-F296 HydrophobicContact CD2-CE2 3.97Å; L201-F296 HydrophobicContact CD2-CZ 3.95Å; L201-F296 HydrophobicContact CG-CE2 4.29Å; L201-F296 HydrophobicContact CG-CZ 3.84Å
202	I	95.7	Very high	94.7	Very high	87 Å²	87	48.2 Å²	48.2	45%	0.446	28%	0.277	S	S	.	.	H	α-helix	trans	-60.9	-47.2	177.1	-71.1	165.4	0	0	0	110.2	F166 A198 Y199 V200 M204 L205 V206	F166-I202 HydrophobicContact CE1-CG2 4.14Å; A198-I202 WeakPolarHBondContact O-CB 3.48Å; A198-I202 WeakPolarHBondContact O-CD1 3.42Å; A198-I202 WeakPolarHBondContact O-CG1 3.46Å; A198-I202 PolarHBondContact O-N 3.03Å; Y199-I202 PolarHBondContact O-N 3.44Å; V200-I202 PolarHBondContact O-N 3.28Å; I202-M204 PolarHBondContact O-N 3.04Å; I202-L205 PolarHBondContact O-N 2.92Å; I202-V206 HydrophobicContact CG2-CG2 4.19Å; I202-V206 WeakPolarHBondContact O-CB 3.4Å; I202-V206 VanDerWaalsContact O-CG2 3.27Å; I202-V206 WeakPolarHBondContact O-CG2 3.25Å; I202-V206 PolarHBondContact O-N 2.85Å
203	L	94.8	Very high	94.9	Very high	4 Å²	4	49.7 Å²	49.7	2%	0.021	27%	0.274	C	S	.	.	H	α-helix	trans	-59.3	-48.3	177.4	-78.9	178.3	0	0	0	112.1	I123 F166 F188 Y199 V200 L205 F207	I123-L203 HydrophobicContact CD1-CD2 4.25Å; F166-L203 HydrophobicContact CB-CD2 3.94Å; F166-L203 HydrophobicContact CD1-CD2 3.94Å; F166-L203 HydrophobicContact CG-CD2 4.4Å; F188-L203 HydrophobicContact CE2-CD1 4.12Å; F188-L203 HydrophobicContact CZ-CD1 3.51Å; Y199-L203 HydrophobicContact CD1-CD1 3.87Å; Y199-L203 HydrophobicContact CE1-CD1 3.29Å; Y199-L203 HydrophobicContact CE1-CG 4.26Å; Y199-L203 HydrophobicContact CE2-CD1 4.11Å; Y199-L203 HydrophobicContact CE2-CG 4.32Å; Y199-L203 VanDerWaalsContact CZ-CD1 3.42Å; Y199-L203 WeakPolarHBondContact O-CG 3.37Å; Y199-L203 PolarHBondContact O-N 3.44Å; V200-L203 PolarHBondContact O-N 3.07Å; L203-L205 VanDerWaalsContact C-N 3.34Å; L203-L205 PolarHBondContact O-N 3.1Å; L203-F207 HydrophobicContact CD2-CD2 3.75Å; L203-F207 HydrophobicContact CD2-CE2 3.71Å; L203-F207 WeakPolarHBondContact O-CB 3.17Å; L203-F207 WeakPolarHBondContact O-CD2 3.33Å; L203-F207 PolarHBondContact O-N 2.94Å
204	M	95.3	Very high	95	Very high	4 Å²	4	48.5 Å²	48.5	2%	0.02	27%	0.269	C	S	.	.	H	α-helix	trans	-65.5	-38.9	179.9	-62.5	-60.6	166.5	0	0	111.6	W119 F188 V200 L201 I202 F208 F209 T288 L292	W119-M204 HydrophobicContact CH2-CE 3.47Å; W119-M204 VanDerWaalsContact CH2-CE 3.47Å; W119-M204 HydrophobicContact CH2-SD 4.25Å; W119-M204 HydrophobicContact CZ2-CE 3.97Å; W119-M204 HydrophobicContact CZ3-CE 4.3Å; F188-M204 HydrophobicContact CD2-CE 3.86Å; F188-M204 HydrophobicContact CE2-CE 3.91Å; V200-M204 HydrophobicContact CG1-CE 4.15Å; V200-M204 HydrophobicContact CG1-CG 4.22Å; V200-M204 VanDerWaalsContact O-CG 3.22Å; V200-M204 WeakPolarHBondContact O-CG 3.38Å; V200-M204 PolarHBondContact O-N 3.39Å; L201-M204 PolarHBondContact O-N 3.02Å; I202-M204 PolarHBondContact O-N 3.04Å; M204-F208 WeakPolarHBondContact O-CA 3.5Å; M204-F208 VanDerWaalsContact O-CB 3.28Å; M204-F208 WeakPolarHBondContact O-CB 3.24Å; M204-F208 PolarHBondContact O-N 3.48Å; M204-F209 HydrophobicContact CB-CD2 4.28Å; M204-F209 HydrophobicContact CB-CE2 4.08Å; M204-F209 WeakPolarHBondContact O-CD2 3.47Å; M204-F209 PolarHBondContact O-N 3.14Å; M204-T288 HydrophobicContact CB-CG2 4.42Å; M204-T288 HydrophobicContact CG-CG2 4.36Å; M204-T288 HydrophobicContact SD-CG2 3.72Å; M204-L292 HydrophobicContact CB-CD2 4.43Å; M204-L292 HydrophobicContact CG-CD2 4.04Å; M204-L292 HydrophobicContact CG-CG 4.35Å
205	L	96.3	Very high	94.9	Very high	91 Å²	91	43.9 Å²	43.9	48%	0.476	24%	0.239	S	C	.	.	I	π-helix	trans	-64.8	-52.4	178	-178.3	64.3	0	0	0	111.4	L201 I202 L203 F209 I210	L201-L205 WeakPolarHBondContact O-CB 3.39Å; L201-L205 PolarHBondContact O-N 3.15Å; I202-L205 PolarHBondContact O-N 2.92Å; L203-L205 VanDerWaalsContact C-N 3.34Å; L203-L205 PolarHBondContact O-N 3.1Å; L205-F209 HydrophobicContact CD1-CB 4.25Å; L205-F209 PolarHBondContact O-N 2.85Å; L205-I210 HydrophobicContact CD1-CD1 4.34Å; L205-I210 HydrophobicContact CD1-CG1 4.16Å; L205-I210 HydrophobicContact CG-CD1 4Å; L205-I210 HydrophobicContact CG-CG1 4.31Å; L205-I210 WeakPolarHBondContact O-CB 3.41Å; L205-I210 WeakPolarHBondContact O-CG1 3.39Å; L205-I210 PolarHBondContact O-N 3.28Å
206	V	96.1	Very high	94.9	Very high	50 Å²	50	45 Å²	45	30%	0.303	24%	0.235	S	C	.	.	I	π-helix	trans	-72.5	-37.6	-173.1	174.9	0	0	0	0	112.1	I202 P211	I202-V206 HydrophobicContact CG2-CG2 4.19Å; I202-V206 WeakPolarHBondContact O-CB 3.4Å; I202-V206 VanDerWaalsContact O-CG2 3.27Å; I202-V206 WeakPolarHBondContact O-CG2 3.25Å; I202-V206 PolarHBondContact O-N 2.85Å; V206-P211 WeakPolarHBondContact O-CD 3.44Å; V206-P211 VanDerWaalsContact O-CG 3.26Å; V206-P211 WeakPolarHBondContact O-CG 3.18Å
207	F	94.7	Very high	94.8	Very high	33 Å²	33	51.6 Å²	51.6	15%	0.145	26%	0.264	C	S	.	.	I	π-helix	trans	-109	-9	-171.3	-60	-63.9	0	0	0	115	I123 L162 F166 L203	I123-F207 HydrophobicContact CB-CD1 4.36Å; I123-F207 HydrophobicContact CB-CG 4.43Å; I123-F207 HydrophobicContact CD1-CD2 3.76Å; I123-F207 HydrophobicContact CD1-CE2 3.96Å; I123-F207 HydrophobicContact CD1-CG 4.11Å; I123-F207 HydrophobicContact CD1-CZ 4.45Å; I123-F207 HydrophobicContact CG1-CB 4.06Å; I123-F207 HydrophobicContact CG1-CD1 4.28Å; I123-F207 HydrophobicContact CG1-CD2 4.03Å; I123-F207 HydrophobicContact CG1-CG 3.85Å; I123-F207 HydrophobicContact CG2-CB 4.44Å; I123-F207 HydrophobicContact CG2-CD1 3.27Å; I123-F207 HydrophobicContact CG2-CD2 4.31Å; I123-F207 HydrophobicContact CG2-CE1 3.37Å; I123-F207 HydrophobicContact CG2-CE2 4.4Å; I123-F207 HydrophobicContact CG2-CG 3.75Å; I123-F207 HydrophobicContact CG2-CZ 3.96Å; L162-F207 HydrophobicContact CD2-CE1 4.17Å; L162-F207 HydrophobicContact CG-CE1 4.33Å; L162-F207 HydrophobicContact CG-CZ 4.31Å; F166-F207 HydrophobicContact CB-CE2 3.6Å; F166-F207 HydrophobicContact CB-CZ 3.82Å; F166-F207 AromaticContact CD1-CE2 3.58Å; F166-F207 HydrophobicContact CD1-CE2 3.58Å; F166-F207 HydrophobicContact CD1-CZ 4.04Å; F166-F207 HydrophobicContact CD2-CE2 4.01Å; F166-F207 AromaticContact CD2-CZ 3.6Å; F166-F207 HydrophobicContact CD2-CZ 3.6Å; F166-F207 HydrophobicContact CE1-CE2 4.2Å; F166-F207 HydrophobicContact CE1-CZ 4.5Å; F166-F207 HydrophobicContact CE2-CZ 4.13Å; F166-F207 AromaticContact CG-CE2 3.44Å; F166-F207 HydrophobicContact CG-CE2 3.44Å; F166-F207 VanDerWaalsContact CG-CE2 3.44Å; F166-F207 AromaticContact CG-CZ 3.53Å; F166-F207 HydrophobicContact CG-CZ 3.53Å; L203-F207 HydrophobicContact CD2-CD2 3.75Å; L203-F207 HydrophobicContact CD2-CE2 3.71Å; L203-F207 WeakPolarHBondContact O-CB 3.17Å; L203-F207 WeakPolarHBondContact O-CD2 3.33Å; L203-F207 PolarHBondContact O-N 2.94Å
208	F	93.9	Very high	94.6	Very high	17 Å²	17	49.9 Å²	49.9	8%	0.075	26%	0.256	C	S	.	.	I	π-helix	trans	-120.9	-63.3	172.9	-179.3	-93.4	0	0	0	112.4	M204 F212 W284 A285 T288	M204-F208 WeakPolarHBondContact O-CA 3.5Å; M204-F208 VanDerWaalsContact O-CB 3.28Å; M204-F208 WeakPolarHBondContact O-CB 3.24Å; M204-F208 PolarHBondContact O-N 3.48Å; F208-F212 WeakPolarHBondContact O-CB 3.47Å; F208-F212 PolarHBondContact O-N 3.2Å; F208-W284 HydrophobicContact CD2-CB 4.26Å; F208-W284 HydrophobicContact CE2-CB 3.91Å; F208-A285 HydrophobicContact CE2-CB 4.3Å; F208-A285 HydrophobicContact CZ-CB 3.7Å; F208-T288 HydrophobicContact CB-CG2 4.37Å; F208-T288 HydrophobicContact CD1-CG2 3.56Å; F208-T288 VanDerWaalsContact CD2-OG1 3.29Å; F208-T288 WeakPolarHBondContact CD2-OG1 3.35Å; F208-T288 HydrophobicContact CE1-CG2 3.94Å; F208-T288 HydrophobicContact CG-CG2 3.91Å; F208-T288 WeakPolarHBondContact CG-OG1 3.31Å
209	F	95.8	Very high	94.2	Very high	81 Å²	81	48.2 Å²	48.2	36%	0.355	24%	0.24	S	C	.	.	I	π-helix	trans	-67.8	-48.8	-170.1	-69.6	-72.6	0	0	0	113.6	M204 L205 F212 L213 T288 L292	M204-F209 HydrophobicContact CB-CD2 4.28Å; M204-F209 HydrophobicContact CB-CE2 4.08Å; M204-F209 WeakPolarHBondContact O-CD2 3.47Å; M204-F209 PolarHBondContact O-N 3.14Å; L205-F209 HydrophobicContact CD1-CB 4.25Å; L205-F209 PolarHBondContact O-N 2.85Å; F209-F212 PolarHBondContact O-N 3.49Å; F209-L213 VanDerWaalsContact O-CG 3.3Å; F209-L213 WeakPolarHBondContact O-CG 3.35Å; F209-L213 PolarHBondContact O-N 2.75Å; F209-T288 HydrophobicContact CE2-CG2 4.17Å; F209-T288 HydrophobicContact CZ-CG2 4.17Å; F209-L292 HydrophobicContact CE2-CD1 4.04Å; F209-L292 HydrophobicContact CZ-CD1 4Å
210	I	95.8	Very high	93.8	Very high	82 Å²	82	52 Å²	52	42%	0.421	26%	0.261	S	S	.	.	H	α-helix	trans	-61.4	-52.3	177.2	-69.6	169.5	0	0	0	110.4	L205 F212 L213 V214	L205-I210 HydrophobicContact CD1-CD1 4.34Å; L205-I210 HydrophobicContact CD1-CG1 4.16Å; L205-I210 HydrophobicContact CG-CD1 4Å; L205-I210 HydrophobicContact CG-CG1 4.31Å; L205-I210 WeakPolarHBondContact O-CB 3.41Å; L205-I210 WeakPolarHBondContact O-CG1 3.39Å; L205-I210 PolarHBondContact O-N 3.28Å; I210-F212 VanDerWaalsContact C-N 3.3Å; I210-F212 PolarHBondContact O-N 3.07Å; I210-L213 PolarHBondContact O-N 3.3Å; I210-V214 HydrophobicContact CG2-CG2 4.42Å; I210-V214 WeakPolarHBondContact O-CG2 3.46Å; I210-V214 PolarHBondContact O-N 3.15Å
211	P	94.2	Very high	93.4	Very high	8 Å²	8	52.8 Å²	52.8	5%	0.052	27%	0.27	C	S	.	.	H	α-helix	trans	-56.6	-42.7	175.5	-29.8	37.7	0	0	0	112.9	L130 V206 V214 M215	L130-P211 HydrophobicContact CD1-CB 4.44Å; L130-P211 HydrophobicContact CD2-CB 4.09Å; L130-P211 HydrophobicContact CD2-CG 4.27Å; V206-P211 WeakPolarHBondContact O-CD 3.44Å; V206-P211 VanDerWaalsContact O-CG 3.26Å; V206-P211 WeakPolarHBondContact O-CG 3.18Å; P211-V214 PolarHBondContact O-N 3.02Å; P211-M215 HydrophobicContact CB-CE 4.27Å; P211-M215 WeakPolarHBondContact O-CB 3.38Å; P211-M215 WeakPolarHBondContact O-CE 3.45Å; P211-M215 WeakPolarHBondContact O-CG 3.14Å; P211-M215 PolarHBondContact O-N 3.5Å
212	F	93.9	Very high	92.8	Very high	51 Å²	51	49.3 Å²	49.3	22%	0.224	25%	0.251	C	S	.	.	H	α-helix	trans	-59.9	-47.1	178	173.9	-100	0	0	0	111.9	F208 F209 I210 M215 L216 F277 T281	F208-F212 WeakPolarHBondContact O-CB 3.47Å; F208-F212 PolarHBondContact O-N 3.2Å; F209-F212 PolarHBondContact O-N 3.49Å; I210-F212 VanDerWaalsContact C-N 3.3Å; I210-F212 PolarHBondContact O-N 3.07Å; F212-M215 PolarHBondContact O-N 2.99Å; F212-L216 HydrophobicContact CE1-CD2 4.23Å; F212-L216 HydrophobicContact CZ-CD2 4.38Å; F212-L216 VanDerWaalsContact O-CB 3.24Å; F212-L216 WeakPolarHBondContact O-CB 3.3Å; F212-L216 PolarHBondContact O-N 3.2Å; F212-F277 AromaticContact CD2-CE2 3.93Å; F212-F277 HydrophobicContact CD2-CE2 3.93Å; F212-F277 AromaticContact CD2-CZ 3.95Å; F212-F277 HydrophobicContact CD2-CZ 3.95Å; F212-F277 HydrophobicContact CE2-CE2 4.13Å; F212-F277 AromaticContact CE2-CZ 3.68Å; F212-F277 HydrophobicContact CE2-CZ 3.68Å; F212-T281 HydrophobicContact CD2-CG2 4.06Å; F212-T281 HydrophobicContact CE2-CG2 3.44Å; F212-T281 VanDerWaalsContact CE2-CG2 3.44Å; F212-T281 HydrophobicContact CZ-CG2 4.32Å
213	L	95.6	Very high	92.2	Very high	108 Å²	108	49 Å²	49	57%	0.565	25%	0.25	S	C	*	.	H	α-helix	trans	-64.7	-43.7	178.6	-70.7	173.6	0	0	0	112.1	F209 I210 L216 F217	F209-L213 VanDerWaalsContact O-CG 3.3Å; F209-L213 WeakPolarHBondContact O-CG 3.35Å; F209-L213 PolarHBondContact O-N 2.75Å; I210-L213 PolarHBondContact O-N 3.3Å; L213-L216 PolarHBondContact O-N 3.46Å; L213-F217 WeakPolarHBondContact O-CB 3.4Å; L213-F217 PolarHBondContact O-N 2.91Å
214	V	95.1	Very high	91.7	Very high	55 Å²	55	54 Å²	54	33%	0.333	28%	0.277	S	S	.	.	H	α-helix	trans	-63.1	-47.5	176.9	174.4	0	0	0	0	110.3	L130 I134 I210 P211 L216 F217 T218	L130-V214 HydrophobicContact CD1-CB 3.95Å; L130-V214 HydrophobicContact CD1-CG1 3.71Å; I134-V214 HydrophobicContact CD1-CG1 4.21Å; I134-V214 HydrophobicContact CG1-CG1 4.17Å; I210-V214 HydrophobicContact CG2-CG2 4.42Å; I210-V214 WeakPolarHBondContact O-CG2 3.46Å; I210-V214 PolarHBondContact O-N 3.15Å; P211-V214 PolarHBondContact O-N 3.02Å; V214-L216 PolarHBondContact O-N 2.78Å; V214-F217 PolarHBondContact O-N 3.37Å; V214-T218 HydrophobicContact CG1-CG2 4.49Å; V214-T218 WeakPolarHBondContact O-CG2 3.38Å; V214-T218 PolarHBondContact O-N 3.1Å; V214-T218 PolarHBondContact O-OG1 3.22Å
215	M	92	Very high	91	Very high	0 Å²	0	55.3 Å²	55.3	0%	0	29%	0.285	C	S	.	.	H	α-helix	trans	-57.7	-50.5	175.5	-79.7	-167.8	-64.6	0	0	111	L129 L130 P211 F212 F217 T218 F219 F277 F280	L129-M215 HydrophobicContact CB-SD 4.49Å; L130-M215 HydrophobicContact CD1-CG 3.75Å; P211-M215 HydrophobicContact CB-CE 4.27Å; P211-M215 WeakPolarHBondContact O-CB 3.38Å; P211-M215 WeakPolarHBondContact O-CE 3.45Å; P211-M215 WeakPolarHBondContact O-CG 3.14Å; P211-M215 PolarHBondContact O-N 3.5Å; F212-M215 PolarHBondContact O-N 2.99Å; M215-F217 VanDerWaalsContact C-N 3.34Å; M215-F217 PolarHBondContact O-N 3.27Å; M215-T218 WeakPolarHBondContact CA-OG1 3.38Å; M215-T218 PolarHBondContact O-N 3.01Å; M215-T218 VanDerWaalsContact O-N 3.13Å; M215-T218 PolarHBondContact O-OG1 2.94Å; M215-F219 VanDerWaalsContact C-CD2 3.46Å; M215-F219 HydrophobicContact CB-CD2 4.3Å; M215-F219 HydrophobicContact CB-CE2 3.82Å; M215-F219 HydrophobicContact CG-CE2 4.42Å; M215-F219 WeakPolarHBondContact O-CD2 3.49Å; M215-F219 WeakPolarHBondContact O-CE2 3.39Å; M215-F219 WeakPolarHBondContact O-CG 3.21Å; M215-F219 PolarHBondContact O-N 3.48Å; M215-F277 HydrophobicContact CB-CD2 3.85Å; M215-F277 HydrophobicContact CB-CE2 3.56Å; M215-F277 HydrophobicContact CB-CZ 4.38Å; M215-F277 HydrophobicContact CE-CD2 4.05Å; M215-F277 HydrophobicContact CE-CE2 4.02Å; M215-F277 HydrophobicContact CG-CD2 4.44Å; M215-F277 HydrophobicContact SD-CD2 3.86Å; M215-F277 HydrophobicContact SD-CE2 4.28Å; M215-F280 HydrophobicContact CE-CD1 3.8Å; M215-F280 HydrophobicContact CE-CE1 3.63Å
216	L	92.5	Very high	90	Very high	66 Å²	66	53 Å²	53	35%	0.346	27%	0.273	S	S	.	.	H	α-helix	trans	-56.1	-47.1	177.4	-178	63.6	0	0	0	111.7	F212 L213 V214 T218 F219 M220 F277	F212-L216 HydrophobicContact CE1-CD2 4.23Å; F212-L216 HydrophobicContact CZ-CD2 4.38Å; F212-L216 VanDerWaalsContact O-CB 3.24Å; F212-L216 WeakPolarHBondContact O-CB 3.3Å; F212-L216 PolarHBondContact O-N 3.2Å; L213-L216 PolarHBondContact O-N 3.46Å; V214-L216 PolarHBondContact O-N 2.78Å; L216-T218 PolarHBondContact O-N 3.4Å; L216-F219 PolarHBondContact O-N 2.77Å; L216-M220 HydrophobicContact CD1-CG 4.41Å; L216-M220 WeakPolarHBondContact O-CG 3.15Å; L216-M220 PolarHBondContact O-N 3.16Å; L216-F277 HydrophobicContact CB-CZ 4.37Å
217	F	92.6	Very high	89.2	Confident	138 Å²	138	59.2 Å²	59.2	61%	0.605	29%	0.291	S	S	*	.	H	α-helix	trans	-57.6	-48.5	175.4	172.1	-97.8	0	0	0	111.8	F137 L213 V214 M215 F219 M220 G221	F137-F217 HydrophobicContact CE1-CE1 4.47Å; F137-F217 HydrophobicContact CE2-CE1 4.29Å; F137-F217 AromaticContact CZ-CE1 3.92Å; F137-F217 HydrophobicContact CZ-CE1 3.92Å; F137-F217 HydrophobicContact CZ-CZ 4.46Å; L213-F217 WeakPolarHBondContact O-CB 3.4Å; L213-F217 PolarHBondContact O-N 2.91Å; V214-F217 PolarHBondContact O-N 3.37Å; M215-F217 VanDerWaalsContact C-N 3.34Å; M215-F217 PolarHBondContact O-N 3.27Å; F217-F219 VanDerWaalsContact C-N 3.27Å; F217-F219 PolarHBondContact O-N 3.41Å; F217-M220 PolarHBondContact O-N 2.83Å; F217-G221 PolarHBondContact O-N 3.34Å
218	T	90	Very high	88.3	Confident	4 Å²	4	62.6 Å²	62.6	3%	0.025	31%	0.307	C	S	.	.	H	α-helix	trans	-59	-39.8	177.5	59.6	0	0	0	0	111.7	I134 F137 V214 M215 L216 G221 I222	I134-T218 HydrophobicContact CG1-CG2 4.47Å; F137-T218 HydrophobicContact CB-CG2 3.72Å; F137-T218 HydrophobicContact CD1-CG2 4.34Å; F137-T218 HydrophobicContact CD2-CG2 4.24Å; F137-T218 WeakPolarHBondContact CD2-O 3.45Å; F137-T218 HydrophobicContact CG-CG2 3.86Å; V214-T218 HydrophobicContact CG1-CG2 4.49Å; V214-T218 WeakPolarHBondContact O-CG2 3.38Å; V214-T218 PolarHBondContact O-N 3.1Å; V214-T218 PolarHBondContact O-OG1 3.22Å; M215-T218 WeakPolarHBondContact CA-OG1 3.38Å; M215-T218 PolarHBondContact O-N 3.01Å; M215-T218 VanDerWaalsContact O-N 3.13Å; M215-T218 PolarHBondContact O-OG1 2.94Å; L216-T218 PolarHBondContact O-N 3.4Å; T218-G221 PolarHBondContact O-N 3.42Å; T218-I222 WeakPolarHBondContact O-CD1 3.42Å; T218-I222 WeakPolarHBondContact O-CG1 3.3Å; T218-I222 PolarHBondContact O-N 3.46Å
219	F	86.1	Confident	87.3	Confident	12 Å²	12	64.7 Å²	64.7	5%	0.053	32%	0.319	C	S	.	.	H	α-helix	trans	-69.4	-43.3	178.5	-67.9	-49.6	0	0	0	113.4	S133 M215 L216 F217 G221 I222 L223 I273 F277	S133-F219 VanDerWaalsContact OG-CZ 3.3Å; S133-F219 WeakPolarHBondContact OG-CZ 3.43Å; M215-F219 VanDerWaalsContact C-CD2 3.46Å; M215-F219 HydrophobicContact CB-CD2 4.3Å; M215-F219 HydrophobicContact CB-CE2 3.82Å; M215-F219 HydrophobicContact CG-CE2 4.42Å; M215-F219 WeakPolarHBondContact O-CD2 3.49Å; M215-F219 WeakPolarHBondContact O-CE2 3.39Å; M215-F219 WeakPolarHBondContact O-CG 3.21Å; M215-F219 PolarHBondContact O-N 3.48Å; L216-F219 PolarHBondContact O-N 2.77Å; F217-F219 VanDerWaalsContact C-N 3.27Å; F217-F219 PolarHBondContact O-N 3.41Å; F219-G221 VanDerWaalsContact C-N 3.28Å; F219-G221 PolarHBondContact O-N 3.5Å; F219-I222 HydrophobicContact CD1-CD1 4.3Å; F219-I222 PolarHBondContact O-N 3.42Å; F219-L223 WeakPolarHBondContact O-CB 3.48Å; F219-L223 WeakPolarHBondContact O-CG 3.19Å; F219-L223 PolarHBondContact O-N 3.45Å; F219-I273 HydrophobicContact CE1-CG2 3.67Å; F219-I273 HydrophobicContact CZ-CG2 3.98Å; F219-F277 HydrophobicContact CD2-CB 4Å; F219-F277 AromaticContact CD2-CD1 3.28Å; F219-F277 HydrophobicContact CD2-CD1 3.28Å; F219-F277 AromaticContact CD2-CD2 3.92Å; F219-F277 HydrophobicContact CD2-CD2 3.92Å; F219-F277 AromaticContact CD2-CE1 3.56Å; F219-F277 HydrophobicContact CD2-CE1 3.56Å; F219-F277 HydrophobicContact CD2-CE2 4.15Å; F219-F277 AromaticContact CD2-CG 3.46Å; F219-F277 HydrophobicContact CD2-CG 3.46Å; F219-F277 VanDerWaalsContact CD2-CG 3.46Å; F219-F277 AromaticContact CD2-CZ 3.98Å; F219-F277 HydrophobicContact CD2-CZ 3.98Å; F219-F277 HydrophobicContact CE1-CB 4.37Å; F219-F277 HydrophobicContact CE2-CB 3.19Å; F219-F277 AromaticContact CE2-CD1 3.38Å; F219-F277 HydrophobicContact CE2-CD1 3.38Å; F219-F277 AromaticContact CE2-CD2 3.32Å; F219-F277 HydrophobicContact CE2-CD2 3.32Å; F219-F277 AromaticContact CE2-CE1 3.99Å; F219-F277 HydrophobicContact CE2-CE1 3.99Å; F219-F277 AromaticContact CE2-CE2 3.93Å; F219-F277 HydrophobicContact CE2-CE2 3.93Å; F219-F277 AromaticContact CE2-CG 2.98Å; F219-F277 HydrophobicContact CE2-CG 2.98Å; F219-F277 HydrophobicContact CE2-CZ 4.23Å; F219-F277 HydrophobicContact CG-CD1 4.22Å; F219-F277 HydrophobicContact CZ-CB 3.41Å; F219-F277 VanDerWaalsContact CZ-CB 3.41Å; F219-F277 HydrophobicContact CZ-CD1 4.32Å; F219-F277 HydrophobicContact CZ-CD2 4.29Å; F219-F277 AromaticContact CZ-CG 3.78Å; F219-F277 HydrophobicContact CZ-CG 3.78Å
220	M	87.8	Confident	86.1	Confident	115 Å²	115	62.9 Å²	62.9	57%	0.567	32%	0.319	S	S	*	.	H	α-helix	trans	-60	-41.4	175.4	-67.5	-53.6	-67.1	0	0	111.1	L216 F217 L223 N224	L216-M220 HydrophobicContact CD1-CG 4.41Å; L216-M220 WeakPolarHBondContact O-CG 3.15Å; L216-M220 PolarHBondContact O-N 3.16Å; F217-M220 PolarHBondContact O-N 2.83Å; M220-L223 PolarHBondContact O-N 3.01Å; M220-N224 VanDerWaalsContact O-CB 3.31Å; M220-N224 WeakPolarHBondContact O-CB 3.17Å; M220-N224 PolarHBondContact O-N 3.04Å
221	G	86.7	Confident	84.7	Confident	18 Å²	18	63.7 Å²	63.7	19%	0.186	32%	0.323	C	S	.	.	H	α-helix	trans	-63.5	-42	174.8	0	0	0	0	0	113.5	F217 T218 F219 T225	F217-G221 PolarHBondContact O-N 3.34Å; T218-G221 PolarHBondContact O-N 3.42Å; F219-G221 VanDerWaalsContact C-N 3.28Å; F219-G221 PolarHBondContact O-N 3.5Å; G221-T225 WeakPolarHBondContact O-CB 3.49Å; G221-T225 PolarHBondContact O-N 3.24Å; G221-T225 PolarHBondContact O-OG1 2.95Å
222	I	83.8	Confident	83.3	Confident	12 Å²	12	70.6 Å²	70.6	6%	0.062	35%	0.348	C	S	.	.	H	α-helix	trans	-63.4	-48.9	175.8	-69.8	164	0	0	0	110.5	R136 F137 I140 V141 T218 F219 N224 T225 I226	R136-I222 HydrophobicContact CB-CD1 4.32Å; F137-I222 HydrophobicContact CB-CD1 4.32Å; F137-I222 HydrophobicContact CB-CG1 4.49Å; F137-I222 HydrophobicContact CD2-CG1 4.41Å; I140-I222 HydrophobicContact CD1-CD1 4.26Å; I140-I222 HydrophobicContact CD1-CG1 4.17Å; I140-I222 HydrophobicContact CD1-CG2 4.05Å; I140-I222 HydrophobicContact CG2-CG2 4.49Å; V141-I222 HydrophobicContact CG2-CG1 4.02Å; T218-I222 WeakPolarHBondContact O-CD1 3.42Å; T218-I222 WeakPolarHBondContact O-CG1 3.3Å; T218-I222 PolarHBondContact O-N 3.46Å; F219-I222 HydrophobicContact CD1-CD1 4.3Å; F219-I222 PolarHBondContact O-N 3.42Å; I222-N224 PolarHBondContact O-N 3.47Å; I222-T225 PolarHBondContact O-N 2.75Å; I222-I226 HydrophobicContact CG2-CD1 3.67Å; I222-I226 HydrophobicContact CG2-CG1 4.43Å; I222-I226 VanDerWaalsContact O-CG1 3.28Å; I222-I226 WeakPolarHBondContact O-CG1 3.47Å; I222-I226 PolarHBondContact O-N 3.35Å
223	L	83	Confident	81.7	Confident	79 Å²	79	73.1 Å²	73.1	41%	0.414	36%	0.363	S	S	.	.	H	α-helix	trans	-61.7	-43	179.9	-73.1	175.5	0	0	0	111.7	F219 M220 I226 R227 L274	F219-L223 WeakPolarHBondContact O-CB 3.48Å; F219-L223 WeakPolarHBondContact O-CG 3.19Å; F219-L223 PolarHBondContact O-N 3.45Å; M220-L223 PolarHBondContact O-N 3.01Å; L223-I226 PolarHBondContact O-N 3.14Å; L223-R227 WeakPolarHBondContact O-CB 3.25Å; L223-R227 PolarHBondContact O-N 2.96Å; L223-L274 HydrophobicContact CD1-CD1 4.26Å; L223-L274 HydrophobicContact CD2-CD1 3.88Å; L223-L274 HydrophobicContact CG-CD1 4.38Å
224	N	84.6	Confident	79.9	Confident	109 Å²	109	75.3 Å²	75.3	58%	0.583	37%	0.37	S	S	*	.	H	α-helix	trans	-62.8	-44	177.4	-169.2	27.1	0	0	0	111.6	M220 I222 I226 R227 H228	M220-N224 VanDerWaalsContact O-CB 3.31Å; M220-N224 WeakPolarHBondContact O-CB 3.17Å; M220-N224 PolarHBondContact O-N 3.04Å; I222-N224 PolarHBondContact O-N 3.47Å; N224-I226 PolarHBondContact O-N 3.26Å; N224-R227 PolarHBondContact O-N 3.32Å; N224-H228 VanDerWaalsContact O-CB 3.3Å; N224-H228 WeakPolarHBondContact O-CB 3.49Å; N224-H228 PolarHBondContact O-N 3.46Å
225	T	80.4	Confident	77.9	Confident	33 Å²	33	76.1 Å²	76.1	20%	0.202	38%	0.378	C	S	.	.	H	α-helix	trans	-62.5	-42.8	177.2	-57.8	0	0	0	0	111.6	I140 G221 I222 N229	I140-T225 HydrophobicContact CG2-CG2 4.4Å; G221-T225 WeakPolarHBondContact O-CB 3.49Å; G221-T225 PolarHBondContact O-N 3.24Å; G221-T225 PolarHBondContact O-OG1 2.95Å; I222-T225 PolarHBondContact O-N 2.75Å; T225-N229 WeakPolarHBondContact O-CB 3.36Å; T225-N229 PolarHBondContact O-N 3.05Å; T225-N229 PolarHBondContact O-ND2 3.07Å
226	I	75.8	Confident	75.9	Confident	43 Å²	43	80.8 Å²	80.8	22%	0.221	40%	0.4	C	S	.	.	H	α-helix	trans	-64.1	-46.5	176.6	-68	167.4	0	0	0	110.5	I222 L223 N224 H228 N229 A230 F270	I222-I226 HydrophobicContact CG2-CD1 3.67Å; I222-I226 HydrophobicContact CG2-CG1 4.43Å; I222-I226 VanDerWaalsContact O-CG1 3.28Å; I222-I226 WeakPolarHBondContact O-CG1 3.47Å; I222-I226 PolarHBondContact O-N 3.35Å; L223-I226 PolarHBondContact O-N 3.14Å; N224-I226 PolarHBondContact O-N 3.26Å; I226-H228 PolarHBondContact O-N 3.22Å; I226-N229 PolarHBondContact O-N 3.19Å; I226-A230 WeakPolarHBondContact O-CB 3.41Å; I226-A230 PolarHBondContact O-N 2.86Å; I226-F270 HydrophobicContact CD1-CB 4.19Å; I226-F270 HydrophobicContact CD1-CD2 3.65Å; I226-F270 HydrophobicContact CD1-CE2 4.45Å; I226-F270 HydrophobicContact CD1-CG 4.25Å; I226-F270 HydrophobicContact CG1-CD2 4.26Å
227	R	79.3	Confident	73.6	Confident	179 Å²	179	81.7 Å²	81.7	68%	0.675	41%	0.409	S	S	*	.	H	α-helix	trans	-60.8	-45.6	178.8	-175.4	176.4	179.2	159	0.1	111.2	L223 N224 N229 A230 I231	L223-R227 WeakPolarHBondContact O-CB 3.25Å; L223-R227 PolarHBondContact O-N 2.96Å; N224-R227 PolarHBondContact O-N 3.32Å; R227-N229 PolarHBondContact O-N 3.3Å; R227-A230 PolarHBondContact O-N 3.48Å; R227-I231 HydrophobicContact CG-CD1 3.89Å; R227-I231 VanDerWaalsContact O-CG1 3.29Å; R227-I231 WeakPolarHBondContact O-CG1 3.33Å; R227-I231 PolarHBondContact O-N 3.41Å
228	H	76.6	Confident	71.4	Confident	104 Å²	104	82.6 Å²	82.6	48%	0.481	42%	0.42	S	S	.	.	H	α-helix	trans	-61.9	-42.3	177.3	-176.1	-84.8	0	0	0	111.9	N224 I226 I231 R232	N224-H228 VanDerWaalsContact O-CB 3.3Å; N224-H228 WeakPolarHBondContact O-CB 3.49Å; N224-H228 PolarHBondContact O-N 3.46Å; I226-H228 PolarHBondContact O-N 3.22Å; H228-I231 PolarHBondContact O-N 3.45Å; H228-R232 WeakPolarHBondContact O-CB 3.46Å; H228-R232 PolarHBondContact O-N 3.22Å
229	N	71.2	Confident	69.3	Low	61 Å²	61	85.9 Å²	85.9	33%	0.326	44%	0.444	S	S	.	.	H	α-helix	trans	-67.5	-36.7	176.6	-68.9	-15.7	0	0	0	112.4	T225 I226 R227 I233	T225-N229 WeakPolarHBondContact O-CB 3.36Å; T225-N229 PolarHBondContact O-N 3.05Å; T225-N229 PolarHBondContact O-ND2 3.07Å; I226-N229 PolarHBondContact O-N 3.19Å; R227-N229 PolarHBondContact O-N 3.3Å; N229-I233 WeakPolarHBondContact O-CD1 3.1Å; N229-I233 VanDerWaalsContact O-CG1 3.23Å; N229-I233 WeakPolarHBondContact O-CG1 3.5Å; N229-I233 PolarHBondContact O-N 2.86Å
230	A	70.8	Confident	67.3	Low	44 Å²	44	93 Å²	93	36%	0.364	48%	0.479	S	S	.	.	H	α-helix	trans	-65.7	-43.4	174.5	0	0	0	0	0	111.8	I226 R227 I233 H234	I226-A230 WeakPolarHBondContact O-CB 3.41Å; I226-A230 PolarHBondContact O-N 2.86Å; R227-A230 PolarHBondContact O-N 3.48Å; A230-I233 PolarHBondContact O-N 2.91Å; A230-H234 PolarHBondContact O-CD2 2.88Å; A230-H234 PolarHBondContact O-N 3.26Å; A230-H234 VanDerWaalsContact O-N 3.1Å
231	I	66.5	Low	65.3	Low	99 Å²	99	92.5 Å²	92.5	51%	0.508	49%	0.486	S	S	.	.	H	α-helix	trans	-63.9	-43.9	176.5	-67.1	166.6	0	0	0	110.8	R227 H228 I233 H234 S235	R227-I231 HydrophobicContact CG-CD1 3.89Å; R227-I231 VanDerWaalsContact O-CG1 3.29Å; R227-I231 WeakPolarHBondContact O-CG1 3.33Å; R227-I231 PolarHBondContact O-N 3.41Å; H228-I231 PolarHBondContact O-N 3.45Å; I231-I233 VanDerWaalsContact C-N 3.25Å; I231-I233 PolarHBondContact O-N 3.29Å; I231-H234 CarbonylContact O-C 3.57Å; I231-H234 PolarHBondContact O-N 2.98Å; I231-H234 VanDerWaalsContact O-N 3.11Å; I231-S235 WeakPolarHBondContact O-CB 3.44Å; I231-S235 PolarHBondContact O-N 2.99Å; I231-S235 PolarHBondContact O-OG 3.49Å
232	R	64.3	Low	63.4	Low	153 Å²	153	98.7 Å²	98.7	58%	0.577	51%	0.514	S	S	*	.	H	α-helix	trans	-59.3	-35.8	177.1	-170.9	-169	-76.6	-163.3	-5.4	112.6	H228 S235 H236	H228-R232 WeakPolarHBondContact O-CB 3.46Å; H228-R232 PolarHBondContact O-N 3.22Å; R232-S235 WeakPolarHBondContact CA-OG 3.24Å; R232-S235 PolarHBondContact O-OG 2.96Å; R232-H236 PolarHBondContact O-N 3.4Å
233	I	60.1	Low	61.4	Low	104 Å²	104	103 Å²	103	53%	0.533	55%	0.545	S	S	.	.	H	α-helix	trans	-70.4	-40	177	-67.9	164.3	0	0	0	110.5	N229 A230 I231	N229-I233 WeakPolarHBondContact O-CD1 3.1Å; N229-I233 VanDerWaalsContact O-CG1 3.23Å; N229-I233 WeakPolarHBondContact O-CG1 3.5Å; N229-I233 PolarHBondContact O-N 2.86Å; A230-I233 PolarHBondContact O-N 2.91Å; I231-I233 VanDerWaalsContact C-N 3.25Å; I231-I233 PolarHBondContact O-N 3.29Å
234	H	58.1	Low	59.4	Low	154 Å²	154	108.2 Å²	108.2	71%	0.713	57%	0.567	S	S	*	*	H	α-helix	trans	-76.6	-20.6	177.3	-75.2	-65	0	0	0	114.5	A230 I231 P237	A230-H234 PolarHBondContact O-CD2 2.88Å; A230-H234 PolarHBondContact O-N 3.26Å; A230-H234 VanDerWaalsContact O-N 3.1Å; I231-H234 CarbonylContact O-C 3.57Å; I231-H234 PolarHBondContact O-N 2.98Å; I231-H234 VanDerWaalsContact O-N 3.11Å; H234-P237 WeakPolarHBondContact O-CD 3.48Å
235	S	54.3	Low	57.5	Low	71 Å²	71	106.4 Å²	106.4	50%	0.497	57%	0.567	S	S	.	*	T	Hydrogen-bonded Turn	trans	-89.1	-7.6	175.9	68.4	0	0	0	0	113.9	I231 R232	I231-S235 WeakPolarHBondContact O-CB 3.44Å; I231-S235 PolarHBondContact O-N 2.99Å; I231-S235 PolarHBondContact O-OG 3.49Å; R232-S235 WeakPolarHBondContact CA-OG 3.24Å; R232-S235 PolarHBondContact O-OG 2.96Å
236	H	48.9	Very low	55.8	Low	99 Å²	99	109.6 Å²	109.6	46%	0.458	59%	0.591	S	S	.	*			trans	-119.3	61.3	170.1	-79	-68.5	0	0	0	112.9	R232 M240	R232-H236 PolarHBondContact O-N 3.4Å; H236-M240 VanDerWaalsContact CE1-SD 3.55Å
237	P	45	Very low	54.5	Low	84 Å²	84	116.6 Å²	116.6	55%	0.545	62%	0.62	S	S	.	*	S	Bend	trans	-81.1	117	147.4	30.4	-16.6	0	0	0	107.1	H234 S239	H234-P237 WeakPolarHBondContact O-CD 3.48Å; P237-S239 PolarHBondContact O-N 3.42Å
238	D	46	Very low	53.1	Low	157 Å²	157	115 Å²	115	84%	0.84	62%	0.624	S	S	*	*	S	Bend	trans	69.9	14.9	155.5	-53.1	-32.3	0	0	0	122
239	S	45.3	Very low	52	Low	74 Å²	74	114.1 Å²	114.1	52%	0.517	64%	0.643	S	S	.	*	S	Bend	trans	-103.8	-11.2	-179.1	67	0	0	0	0	117.8	P237	P237-S239 PolarHBondContact O-N 3.42Å
240	M	45.5	Very low	50.8	Low	160 Å²	160	118.5 Å²	118.5	79%	0.788	67%	0.666	S	S	*	*	S	Bend	trans	-110.6	16.9	-174.7	-72.3	-163.9	82.9	0	0	116.1	H236	H236-M240 VanDerWaalsContact CE1-SD 3.55Å
241	C	45.4	Very low	50	Low	106 Å²	106	125 Å²	125	72%	0.716	69%	0.693	S	S	*	*	S	Bend	trans	-127.2	0.6	170.8	-151.5	0	0	0	0	114.9
242	L	46.9	Very low	48.8	Very low	148 Å²	148	125 Å²	125	78%	0.775	70%	0.702	S	S	*	*	S	Bend	trans	-110.7	-5.1	-175.8	-147.2	74.4	0	0	0	115.1
243	S	42.4	Very low	47.8	Very low	102 Å²	102	125.8 Å²	125.8	71%	0.713	72%	0.717	S	S	*	*	S	Bend	trans	-99.7	-17.9	-178.8	140.2	0	0	0	0	114.4
244	Q	41	Very low	46.7	Very low	189 Å²	189	129.5 Å²	129.5	88%	0.883	73%	0.732	S	S	*	*	S	Bend	trans	-112.7	-9.9	-179.1	-124.7	173.7	8.2	0	0	114.1
245	A	44.1	Very low	45.7	Very low	70 Å²	70	131.3 Å²	131.3	58%	0.579	74%	0.738	S	S	*	*	S	Bend	trans	-91.6	-5.1	177.2	0	0	0	0	0	113.7
246	S	43.8	Very low	44.7	Very low	100 Å²	100	133 Å²	133	70%	0.699	75%	0.747	S	S	*	*	S	Bend	trans	-85.5	-0.9	-180	61.7	0	0	0	0	114.6
247	K	48.7	Very low	44.2	Very low	190 Å²	190	136.9 Å²	136.9	83%	0.826	76%	0.763	S	S	*	*	S	Bend	trans	-114.1	-6.1	-177.7	-106.7	-173.1	179	-175.5	0	116.9
248	L	50.5	Low	43.7	Very low	147 Å²	147	140.2 Å²	140.2	77%	0.77	77%	0.771	S	S	*	*	S	Bend	trans	-140.8	99	168.2	-95.8	104	0	0	0	109.2	L250	L248-L250 PolarHBondContact O-N 2.93Å
249	G	52.4	Low	43.4	Very low	85 Å²	85	140.4 Å²	140.4	88%	0.876	77%	0.769	S	S	*	*			trans	-63	103.2	169.4	0	0	0	0	0	109.9
250	L	45.8	Very low	43	Very low	153 Å²	153	142.5 Å²	142.5	80%	0.801	77%	0.774	S	S	*	*			trans	-148.6	103.9	160.8	-110.1	161.1	0	0	0	108.4	L248 S252	L248-L250 PolarHBondContact O-N 2.93Å; L250-S252 PolarHBondContact O-N 3.26Å
251	L	55	Low	42.8	Very low	179 Å²	179	141.2 Å²	141.2	94%	0.937	77%	0.77	S	S	*	*			trans	-59.8	110	166.2	-85.2	147.6	0	0	0	109.1
252	S	40.1	Very low	42.6	Very low	99 Å²	99	140.9 Å²	140.9	69%	0.692	76%	0.76	S	S	*	*			trans	-170.2	111.5	159.1	165.8	0	0	0	0	111.5	L250 Q254	L250-S252 PolarHBondContact O-N 3.26Å; S252-Q254 PolarHBondContact O-N 2.87Å
253	L	43.6	Very low	42.4	Very low	171 Å²	171	138.2 Å²	138.2	90%	0.895	75%	0.745	S	S	*	*			trans	44.8	72.3	147.6	-78.6	162.4	0	0	0	117.6
254	Q	37.9	Very low	42.3	Very low	181 Å²	181	136.4 Å²	136.4	85%	0.846	73%	0.732	S	S	*	*			trans	-122.4	89.1	150.4	-159.7	164.1	-38.4	0	0	108.9	S252 P256	S252-Q254 PolarHBondContact O-N 2.87Å; Q254-P256 WeakPolarHBondContact O-CD 3.25Å; Q254-P256 VanDerWaalsContact O-N 3.12Å
255	K	36.1	Very low	42.5	Very low	192 Å²	192	133.8 Å²	133.8	84%	0.835	72%	0.719	S	S	*	*			trans	-47.9	120.5	158.2	-120.4	173.8	-177.5	168.2	0	105.7	F257	K255-F257 PolarHBondContact O-N 3.28Å
256	P	34.3	Very low	42.7	Very low	108 Å²	108	134.9 Å²	134.9	70%	0.701	71%	0.71	S	S	*	*			trans	-57.2	121.8	173.1	23	-30.1	0	0	0	105.8	Q254 Q258	Q254-P256 WeakPolarHBondContact O-CD 3.25Å; Q254-P256 VanDerWaalsContact O-N 3.12Å; P256-Q258 PolarHBondContact O-N 3.41Å
257	F	38.1	Very low	43	Very low	179 Å²	179	132.8 Å²	132.8	79%	0.785	69%	0.693	S	S	*	*			trans	-65.8	86.6	170.9	-168.2	-102.5	0	0	0	105.7	K255 M259	K255-F257 PolarHBondContact O-N 3.28Å; F257-M259 HydrophobicContact CD1-CG 3.46Å; F257-M259 VanDerWaalsContact CD1-CG 3.46Å; F257-M259 HydrophobicContact CD1-SD 4.2Å; F257-M259 HydrophobicContact CE1-CE 3.99Å; F257-M259 HydrophobicContact CE1-CG 3.52Å; F257-M259 HydrophobicContact CE1-SD 3.91Å; F257-M259 PolarHBondContact O-N 2.91Å
258	Q	35	Very low	43.3	Very low	154 Å²	154	131.9 Å²	131.9	72%	0.72	69%	0.685	S	S	*	*			trans	-70.6	83.8	-174.8	-149	-174.1	1.4	0	0	106.2	P256 N260	P256-Q258 PolarHBondContact O-N 3.41Å; Q258-N260 HydrophobicContact CG-CB 4.2Å; Q258-N260 PolarHBondContact O-N 3.18Å
259	M	38.7	Very low	43.6	Very low	162 Å²	162	127.1 Å²	127.1	80%	0.798	67%	0.667	S	S	*	*			trans	-73.2	50.6	163.2	-61.5	-155.5	95.6	0	0	109.5	F257	F257-M259 HydrophobicContact CD1-CG 3.46Å; F257-M259 VanDerWaalsContact CD1-CG 3.46Å; F257-M259 HydrophobicContact CD1-SD 4.2Å; F257-M259 HydrophobicContact CE1-CE 3.99Å; F257-M259 HydrophobicContact CE1-CG 3.52Å; F257-M259 HydrophobicContact CE1-SD 3.91Å; F257-M259 PolarHBondContact O-N 2.91Å
260	N	38.2	Very low	44.2	Very low	117 Å²	117	124.5 Å²	124.5	63%	0.626	63%	0.631	S	S	*	*			trans	-98.7	138.7	160.8	-98.8	-55.2	0	0	0	106.8	Q258	Q258-N260 HydrophobicContact CG-CB 4.2Å; Q258-N260 PolarHBondContact O-N 3.18Å
261	I	41.6	Very low	45.3	Very low	134 Å²	134	120.3 Å²	120.3	69%	0.687	61%	0.612	S	S	*	*	S	Bend	trans	90.2	42.1	174.5	-37.7	154.1	0	0	0	115.9
262	D	40.6	Very low	46.1	Very low	98 Å²	98	112.3 Å²	112.3	52%	0.524	57%	0.571	S	S	.	*	S	Bend	trans	-137.6	5	152.8	-156.3	33.9	0	0	0	114.9
263	M	42	Very low	47.6	Very low	92 Å²	92	108.4 Å²	108.4	45%	0.453	54%	0.542	S	S	.	.	H	α-helix	trans	-85.3	-32.6	169.5	-74.1	-63.3	116.3	0	0	112.2	K266 T267	M263-K266 HydrophobicContact CE-CD 4.18Å; M263-K266 PolarHBondContact O-N 3.44Å; M263-T267 PolarHBondContact O-N 3.21Å; M263-T267 PolarHBondContact O-OG1 3.38Å
264	S	41.8	Very low	49.1	Very low	64 Å²	64	103.1 Å²	103.1	45%	0.448	51%	0.514	S	S	.	.	H	α-helix	trans	-72.7	-32.5	-176.1	64.8	0	0	0	0	114.2	R268	S264-R268 WeakPolarHBondContact O-CG 3.36Å; S264-R268 PolarHBondContact O-N 2.73Å
265	F	43.3	Very low	51.2	Low	135 Å²	135	97.3 Å²	97.3	59%	0.592	49%	0.488	S	S	*	.	H	α-helix	trans	-74.6	-38.4	172.8	-84.7	-84.2	0	0	0	112	R268 A269	F265-R268 PolarHBondContact O-N 3.25Å; F265-A269 PolarHBondContact O-N 2.88Å
266	K	48.7	Very low	53.4	Low	93 Å²	93	88.5 Å²	88.5	40%	0.404	45%	0.45	S	S	.	.	H	α-helix	trans	-61.9	-47.4	173.7	-104	175.3	175.2	161.7	0	111.9	M263 R268 A269 F270	M263-K266 HydrophobicContact CE-CD 4.18Å; M263-K266 PolarHBondContact O-N 3.44Å; K266-R268 VanDerWaalsContact C-N 3.31Å; K266-R268 PolarHBondContact O-N 3.04Å; K266-A269 PolarHBondContact O-N 2.84Å; K266-F270 VanDerWaalsContact C-CD2 3.47Å; K266-F270 HydrophobicContact CB-CE1 4.47Å; K266-F270 HydrophobicContact CB-CE2 3.62Å; K266-F270 HydrophobicContact CB-CZ 3.54Å; K266-F270 HydrophobicContact CD-CZ 4.18Å; K266-F270 HydrophobicContact CG-CE1 4.4Å; K266-F270 HydrophobicContact CG-CE2 4.22Å; K266-F270 HydrophobicContact CG-CZ 3.62Å; K266-F270 VanDerWaalsContact O-CD1 3.28Å; K266-F270 WeakPolarHBondContact O-CD1 3.16Å; K266-F270 WeakPolarHBondContact O-CD2 3.34Å; K266-F270 WeakPolarHBondContact O-CE1 3.24Å; K266-F270 VanDerWaalsContact O-CE2 3.26Å; K266-F270 WeakPolarHBondContact O-CE2 3.01Å; K266-F270 WeakPolarHBondContact O-CG 3.43Å; K266-F270 WeakPolarHBondContact O-CZ 3.28Å; K266-F270 PolarHBondContact O-N 2.89Å
267	T	49.8	Very low	55.6	Low	56 Å²	56	84.4 Å²	84.4	34%	0.344	42%	0.422	S	S	.	.	H	α-helix	trans	-59.9	-35.7	178.3	-52.5	0	0	0	0	113.4	M263 A269 F270 T271	M263-T267 PolarHBondContact O-N 3.21Å; M263-T267 PolarHBondContact O-OG1 3.38Å; T267-A269 PolarHBondContact O-N 3.06Å; T267-F270 PolarHBondContact O-N 3.01Å; T267-T271 PolarHBondContact O-N 3.38Å; T267-T271 PolarHBondContact O-OG1 2.86Å
268	R	55.9	Low	57.9	Low	170 Å²	170	78.4 Å²	78.4	64%	0.642	40%	0.402	S	S	*	.	H	α-helix	trans	-67.4	-34.7	177.6	-75.6	177.7	179.8	-178	0.5	113.6	S264 F265 K266 T272 R331	S264-R268 WeakPolarHBondContact O-CG 3.36Å; S264-R268 PolarHBondContact O-N 2.73Å; F265-R268 PolarHBondContact O-N 3.25Å; K266-R268 VanDerWaalsContact C-N 3.31Å; K266-R268 PolarHBondContact O-N 3.04Å; R268-T272 PolarHBondContact O-OG1 2.93Å; R268-R331 PolarHBondContact O-NH2 2.74Å
269	A	57.8	Low	60.6	Low	48 Å²	48	72.2 Å²	72.2	40%	0.397	37%	0.374	S	S	.	.	H	α-helix	trans	-67.5	-39.5	172.5	0	0	0	0	0	110.7	F265 K266 T267 T272 I273	F265-A269 PolarHBondContact O-N 2.88Å; K266-A269 PolarHBondContact O-N 2.84Å; T267-A269 PolarHBondContact O-N 3.06Å; A269-T272 VanDerWaalsContact O-CB 3.28Å; A269-T272 WeakPolarHBondContact O-CB 3.26Å; A269-T272 PolarHBondContact O-N 3.38Å; A269-T272 VanDerWaalsContact O-N 3.13Å; A269-T272 PolarHBondContact O-OG1 2.9Å; A269-I273 WeakPolarHBondContact O-CD1 3.09Å
270	F	65.1	Low	62.9	Low	29 Å²	29	64.8 Å²	64.8	13%	0.127	34%	0.338	C	S	.	.	H	α-helix	trans	-66.4	-45.4	-177.6	-51.3	-28.5	0	0	0	113.5	I140 I226 K266 T267 T272 I273 L274	I140-F270 HydrophobicContact CD1-CD1 3.31Å; I140-F270 HydrophobicContact CD1-CD2 4.44Å; I140-F270 HydrophobicContact CD1-CE1 3.16Å; I140-F270 HydrophobicContact CD1-CE2 4.31Å; I140-F270 HydrophobicContact CD1-CG 4Å; I140-F270 HydrophobicContact CD1-CZ 3.7Å; I140-F270 HydrophobicContact CG1-CD1 4.2Å; I140-F270 HydrophobicContact CG1-CE1 3.52Å; I140-F270 HydrophobicContact CG1-CZ 3.69Å; I226-F270 HydrophobicContact CD1-CB 4.19Å; I226-F270 HydrophobicContact CD1-CD2 3.65Å; I226-F270 HydrophobicContact CD1-CE2 4.45Å; I226-F270 HydrophobicContact CD1-CG 4.25Å; I226-F270 HydrophobicContact CG1-CD2 4.26Å; K266-F270 VanDerWaalsContact C-CD2 3.47Å; K266-F270 HydrophobicContact CB-CE1 4.47Å; K266-F270 HydrophobicContact CB-CE2 3.62Å; K266-F270 HydrophobicContact CB-CZ 3.54Å; K266-F270 HydrophobicContact CD-CZ 4.18Å; K266-F270 HydrophobicContact CG-CE1 4.4Å; K266-F270 HydrophobicContact CG-CE2 4.22Å; K266-F270 HydrophobicContact CG-CZ 3.62Å; K266-F270 VanDerWaalsContact O-CD1 3.28Å; K266-F270 WeakPolarHBondContact O-CD1 3.16Å; K266-F270 WeakPolarHBondContact O-CD2 3.34Å; K266-F270 WeakPolarHBondContact O-CE1 3.24Å; K266-F270 VanDerWaalsContact O-CE2 3.26Å; K266-F270 WeakPolarHBondContact O-CE2 3.01Å; K266-F270 WeakPolarHBondContact O-CG 3.43Å; K266-F270 WeakPolarHBondContact O-CZ 3.28Å; K266-F270 PolarHBondContact O-N 2.89Å; T267-F270 PolarHBondContact O-N 3.01Å; F270-T272 PolarHBondContact O-N 3.46Å; F270-I273 PolarHBondContact O-N 3.02Å; F270-I273 VanDerWaalsContact O-N 3.13Å; F270-L274 PolarHBondContact O-N 3.47Å; F270-L274 VanDerWaalsContact O-N 3.1Å
271	T	69	Low	65.3	Low	65 Å²	65	60.4 Å²	60.4	40%	0.399	32%	0.315	S	S	.	.	H	α-helix	trans	-62.8	-17.7	176.7	-49.4	0	0	0	0	111.2	T267 I275 R331	T267-T271 PolarHBondContact O-N 3.38Å; T267-T271 PolarHBondContact O-OG1 2.86Å; T271-I275 VanDerWaalsContact O-CG1 3.25Å; T271-I275 WeakPolarHBondContact O-CG1 3Å; T271-I275 PolarHBondContact O-N 3.39Å; T271-R331 VanDerWaalsContact C-NH1 3.26Å; T271-R331 PolarHBondContact O-NH1 3.14Å
272	T	70.7	Confident	67.7	Low	11 Å²	11	58.7 Å²	58.7	7%	0.067	31%	0.311	C	S	.	.	H	α-helix	trans	-75.9	-43.8	177	-49.2	0	0	0	0	110.3	R268 A269 F270 I275 L276 I327 R331	R268-T272 PolarHBondContact O-OG1 2.93Å; A269-T272 VanDerWaalsContact O-CB 3.28Å; A269-T272 WeakPolarHBondContact O-CB 3.26Å; A269-T272 PolarHBondContact O-N 3.38Å; A269-T272 VanDerWaalsContact O-N 3.13Å; A269-T272 PolarHBondContact O-OG1 2.9Å; F270-T272 PolarHBondContact O-N 3.46Å; T272-I275 PolarHBondContact O-N 3.42Å; T272-L276 HydrophobicContact CG2-CD1 4.4Å; T272-L276 VanDerWaalsContact O-CG 3.31Å; T272-L276 WeakPolarHBondContact O-CG 3.35Å; T272-L276 PolarHBondContact O-N 3.28Å; T272-I327 HydrophobicContact CG2-CG2 3.99Å; T272-R331 HydrophobicContact CG2-CB 3.62Å; T272-R331 HydrophobicContact CG2-CG 4.03Å; T272-R331 WeakPolarHBondContact OG1-CB 3.49Å; T272-R331 PolarHBondContact OG1-NH2 3.05Å
273	I	70.8	Confident	70.2	Confident	17 Å²	17	54.3 Å²	54.3	9%	0.087	29%	0.288	C	S	.	.	H	α-helix	trans	-68.2	-38.8	179.1	-57.5	136.5	0	0	0	110.5	I132 R136 F219 A269 F270 I275 L276 F277	I132-I273 HydrophobicContact CG2-CG1 4.45Å; I132-I273 HydrophobicContact CG2-CG2 4.36Å; R136-I273 HydrophobicContact CB-CD1 4.18Å; R136-I273 HydrophobicContact CG-CD1 3.46Å; R136-I273 VanDerWaalsContact CG-CD1 3.46Å; R136-I273 HydrophobicContact CG-CG1 4.22Å; F219-I273 HydrophobicContact CE1-CG2 3.67Å; F219-I273 HydrophobicContact CZ-CG2 3.98Å; A269-I273 WeakPolarHBondContact O-CD1 3.09Å; F270-I273 PolarHBondContact O-N 3.02Å; F270-I273 VanDerWaalsContact O-N 3.13Å; I273-I275 VanDerWaalsContact C-N 3.31Å; I273-I275 PolarHBondContact O-N 2.7Å; I273-L276 PolarHBondContact O-N 3.14Å; I273-F277 PolarHBondContact O-N 3.09Å
274	L	75.3	Confident	72.5	Confident	61 Å²	61	50.4 Å²	50.4	32%	0.319	27%	0.268	S	S	.	.	H	α-helix	trans	-59	-43.8	173.5	-174.3	145.5	0	0	0	111.3	L223 F270 F277 S278	L223-L274 HydrophobicContact CD1-CD1 4.26Å; L223-L274 HydrophobicContact CD2-CD1 3.88Å; L223-L274 HydrophobicContact CG-CD1 4.38Å; F270-L274 PolarHBondContact O-N 3.47Å; F270-L274 VanDerWaalsContact O-N 3.1Å; L274-F277 PolarHBondContact O-N 3.32Å; L274-S278 WeakPolarHBondContact O-CB 3.18Å; L274-S278 PolarHBondContact O-N 3.23Å; L274-S278 PolarHBondContact O-OG 2.9Å
275	I	82.9	Confident	75	Confident	59 Å²	59	49 Å²	49	30%	0.303	26%	0.26	S	S	.	.	H	α-helix	trans	-63.3	-44.2	175.2	-70.4	-177.8	0	0	0	111.1	T271 T272 I273 F277 S278 V279 I327	T271-I275 VanDerWaalsContact O-CG1 3.25Å; T271-I275 WeakPolarHBondContact O-CG1 3Å; T271-I275 PolarHBondContact O-N 3.39Å; T272-I275 PolarHBondContact O-N 3.42Å; I273-I275 VanDerWaalsContact C-N 3.31Å; I273-I275 PolarHBondContact O-N 2.7Å; I275-F277 VanDerWaalsContact C-N 3.33Å; I275-F277 PolarHBondContact O-N 3.43Å; I275-S278 PolarHBondContact O-N 2.95Å; I275-V279 HydrophobicContact CG2-CG2 4.21Å; I275-V279 WeakPolarHBondContact O-CB 3.3Å; I275-V279 VanDerWaalsContact O-CG2 3.3Å; I275-V279 WeakPolarHBondContact O-CG2 3.37Å; I275-V279 PolarHBondContact O-N 2.85Å; I275-I327 HydrophobicContact CG2-CD1 3.93Å; I275-I327 HydrophobicContact CG2-CG1 4.01Å; I275-I327 HydrophobicContact CG2-CG2 4.08Å
276	L	81.1	Confident	77.5	Confident	6 Å²	6	44.7 Å²	44.7	3%	0.031	25%	0.246	C	C	.	.	H	α-helix	trans	-60.5	-41.9	179.2	-68	167.8	0	0	0	112.1	L129 T272 I273 F280 I327 Y328	L129-L276 HydrophobicContact CD2-CB 4.32Å; T272-L276 HydrophobicContact CG2-CD1 4.4Å; T272-L276 VanDerWaalsContact O-CG 3.31Å; T272-L276 WeakPolarHBondContact O-CG 3.35Å; T272-L276 PolarHBondContact O-N 3.28Å; I273-L276 PolarHBondContact O-N 3.14Å; L276-F280 WeakPolarHBondContact O-CB 3.29Å; L276-F280 PolarHBondContact O-N 2.02Å; L276-I327 HydrophobicContact CD2-CB 4.19Å; L276-I327 HydrophobicContact CD2-CD1 3.86Å; L276-I327 HydrophobicContact CD2-CG2 3.83Å; L276-I327 HydrophobicContact CG-CG2 4.17Å; L276-Y328 HydrophobicContact CD1-CE1 3.79Å; L276-Y328 HydrophobicContact CD2-CE1 3.68Å; L276-Y328 HydrophobicContact CG-CE1 4.35Å
277	F	82.4	Confident	79.6	Confident	23 Å²	23	40.4 Å²	40.4	10%	0.101	23%	0.227	C	C	.	.	H	α-helix	trans	-67.2	-44.3	174.8	167.7	-111.5	0	0	0	113.1	F212 M215 L216 F219 I273 L274 I275 V279 F280 T281	F212-F277 AromaticContact CD2-CE2 3.93Å; F212-F277 HydrophobicContact CD2-CE2 3.93Å; F212-F277 AromaticContact CD2-CZ 3.95Å; F212-F277 HydrophobicContact CD2-CZ 3.95Å; F212-F277 HydrophobicContact CE2-CE2 4.13Å; F212-F277 AromaticContact CE2-CZ 3.68Å; F212-F277 HydrophobicContact CE2-CZ 3.68Å; M215-F277 HydrophobicContact CB-CD2 3.85Å; M215-F277 HydrophobicContact CB-CE2 3.56Å; M215-F277 HydrophobicContact CB-CZ 4.38Å; M215-F277 HydrophobicContact CE-CD2 4.05Å; M215-F277 HydrophobicContact CE-CE2 4.02Å; M215-F277 HydrophobicContact CG-CD2 4.44Å; M215-F277 HydrophobicContact SD-CD2 3.86Å; M215-F277 HydrophobicContact SD-CE2 4.28Å; L216-F277 HydrophobicContact CB-CZ 4.37Å; F219-F277 HydrophobicContact CD2-CB 4Å; F219-F277 AromaticContact CD2-CD1 3.28Å; F219-F277 HydrophobicContact CD2-CD1 3.28Å; F219-F277 AromaticContact CD2-CD2 3.92Å; F219-F277 HydrophobicContact CD2-CD2 3.92Å; F219-F277 AromaticContact CD2-CE1 3.56Å; F219-F277 HydrophobicContact CD2-CE1 3.56Å; F219-F277 HydrophobicContact CD2-CE2 4.15Å; F219-F277 AromaticContact CD2-CG 3.46Å; F219-F277 HydrophobicContact CD2-CG 3.46Å; F219-F277 VanDerWaalsContact CD2-CG 3.46Å; F219-F277 AromaticContact CD2-CZ 3.98Å; F219-F277 HydrophobicContact CD2-CZ 3.98Å; F219-F277 HydrophobicContact CE1-CB 4.37Å; F219-F277 HydrophobicContact CE2-CB 3.19Å; F219-F277 AromaticContact CE2-CD1 3.38Å; F219-F277 HydrophobicContact CE2-CD1 3.38Å; F219-F277 AromaticContact CE2-CD2 3.32Å; F219-F277 HydrophobicContact CE2-CD2 3.32Å; F219-F277 AromaticContact CE2-CE1 3.99Å; F219-F277 HydrophobicContact CE2-CE1 3.99Å; F219-F277 AromaticContact CE2-CE2 3.93Å; F219-F277 HydrophobicContact CE2-CE2 3.93Å; F219-F277 AromaticContact CE2-CG 2.98Å; F219-F277 HydrophobicContact CE2-CG 2.98Å; F219-F277 HydrophobicContact CE2-CZ 4.23Å; F219-F277 HydrophobicContact CG-CD1 4.22Å; F219-F277 HydrophobicContact CZ-CB 3.41Å; F219-F277 VanDerWaalsContact CZ-CB 3.41Å; F219-F277 HydrophobicContact CZ-CD1 4.32Å; F219-F277 HydrophobicContact CZ-CD2 4.29Å; F219-F277 AromaticContact CZ-CG 3.78Å; F219-F277 HydrophobicContact CZ-CG 3.78Å; I273-F277 PolarHBondContact O-N 3.09Å; L274-F277 PolarHBondContact O-N 3.32Å; I275-F277 VanDerWaalsContact C-N 3.33Å; I275-F277 PolarHBondContact O-N 3.43Å; F277-V279 VanDerWaalsContact C-N 3.28Å; F277-V279 PolarHBondContact O-N 3.46Å; F277-F280 PolarHBondContact O-N 3.1Å; F277-T281 VanDerWaalsContact CE2-OG1 3.3Å; F277-T281 WeakPolarHBondContact CE2-OG1 3.04Å; F277-T281 WeakPolarHBondContact CZ-OG1 3.25Å; F277-T281 WeakPolarHBondContact O-CB 3.21Å; F277-T281 PolarHBondContact O-N 3.05Å; F277-T281 PolarHBondContact O-OG1 2.86Å
278	S	86.2	Confident	81.7	Confident	52 Å²	52	37.9 Å²	37.9	36%	0.364	21%	0.212	S	C	.	.	H	α-helix	trans	-60	-43.2	177.3	-64.8	0	0	0	0	110.7	L274 I275 T281 V282	L274-S278 WeakPolarHBondContact O-CB 3.18Å; L274-S278 PolarHBondContact O-N 3.23Å; L274-S278 PolarHBondContact O-OG 2.9Å; I275-S278 PolarHBondContact O-N 2.95Å; S278-T281 PolarHBondContact O-N 3.45Å; S278-V282 WeakPolarHBondContact O-CB 3.46Å; S278-V282 VanDerWaalsContact O-CG2 3.25Å; S278-V282 WeakPolarHBondContact O-CG2 3.37Å; S278-V282 PolarHBondContact O-N 3.42Å
279	V	90.2	Very high	83.6	Confident	24 Å²	24	32.4 Å²	32.4	15%	0.145	20%	0.202	C	C	.	.	H	α-helix	trans	-64.3	-45.6	175.9	169.4	0	0	0	0	111.1	I275 F277 T281 V282 C283 L323 I327	I275-V279 HydrophobicContact CG2-CG2 4.21Å; I275-V279 WeakPolarHBondContact O-CB 3.3Å; I275-V279 VanDerWaalsContact O-CG2 3.3Å; I275-V279 WeakPolarHBondContact O-CG2 3.37Å; I275-V279 PolarHBondContact O-N 2.85Å; F277-V279 VanDerWaalsContact C-N 3.28Å; F277-V279 PolarHBondContact O-N 3.46Å; V279-T281 PolarHBondContact O-N 2.94Å; V279-V282 PolarHBondContact O-N 3.01Å; V279-C283 WeakPolarHBondContact O-CB 3.13Å; V279-C283 PolarHBondContact O-N 3.44Å; V279-C283 PolarHBondContact O-SG 3.06Å; V279-L323 HydrophobicContact CG1-CB 4.09Å; V279-L323 HydrophobicContact CG1-CD1 3.69Å; V279-L323 HydrophobicContact CG2-CD1 4.41Å; V279-I327 HydrophobicContact CB-CD1 4.39Å; V279-I327 HydrophobicContact CG1-CD1 4.47Å; V279-I327 HydrophobicContact CG2-CD1 3.97Å
280	F	87.7	Confident	85.4	Confident	7 Å²	7	30.6 Å²	30.6	3%	0.031	19%	0.185	C	C	.	.	H	α-helix	trans	-55.1	-51	174.3	174.5	-96.2	0	0	0	111.5	L129 M215 L276 F277 C283 W284	L129-F280 HydrophobicContact CD1-CB 3.85Å; L129-F280 HydrophobicContact CD1-CD2 3.54Å; L129-F280 HydrophobicContact CD1-CE2 4.36Å; L129-F280 HydrophobicContact CD1-CG 3.86Å; M215-F280 HydrophobicContact CE-CD1 3.8Å; M215-F280 HydrophobicContact CE-CE1 3.63Å; L276-F280 WeakPolarHBondContact O-CB 3.29Å; L276-F280 PolarHBondContact O-N 2.02Å; F277-F280 PolarHBondContact O-N 3.1Å; F280-C283 PolarHBondContact O-N 2.99Å; F280-W284 AromaticContact CD2-CD1 3.53Å; F280-W284 HydrophobicContact CD2-CG 4.27Å; F280-W284 AromaticContact CE2-CD1 3.6Å; F280-W284 AromaticContact CE2-CG 3.99Å; F280-W284 HydrophobicContact CE2-CG 3.99Å; F280-W284 HydrophobicContact CZ-CG 4.36Å; F280-W284 VanDerWaalsContact O-CB 3.24Å; F280-W284 WeakPolarHBondContact O-CB 3.2Å; F280-W284 PolarHBondContact O-N 3.04Å
281	T	88.6	Confident	86.8	Confident	25 Å²	25	29.2 Å²	29.2	15%	0.153	18%	0.179	C	C	.	.	H	α-helix	trans	-63.1	-50	-178.1	-58.5	0	0	0	0	111.9	F212 F277 S278 V279 C283 W284 A285	F212-T281 HydrophobicContact CD2-CG2 4.06Å; F212-T281 HydrophobicContact CE2-CG2 3.44Å; F212-T281 VanDerWaalsContact CE2-CG2 3.44Å; F212-T281 HydrophobicContact CZ-CG2 4.32Å; F277-T281 VanDerWaalsContact CE2-OG1 3.3Å; F277-T281 WeakPolarHBondContact CE2-OG1 3.04Å; F277-T281 WeakPolarHBondContact CZ-OG1 3.25Å; F277-T281 WeakPolarHBondContact O-CB 3.21Å; F277-T281 PolarHBondContact O-N 3.05Å; F277-T281 PolarHBondContact O-OG1 2.86Å; S278-T281 PolarHBondContact O-N 3.45Å; V279-T281 PolarHBondContact O-N 2.94Å; T281-C283 VanDerWaalsContact C-N 3.28Å; T281-C283 PolarHBondContact O-N 3.46Å; T281-W284 PolarHBondContact O-N 2.95Å; T281-A285 HydrophobicContact CG2-CB 4.42Å; T281-A285 WeakPolarHBondContact O-CB 3.31Å; T281-A285 PolarHBondContact O-N 3.5Å
282	V	91.8	Very high	88	Confident	98 Å²	98	27.7 Å²	27.7	59%	0.594	17%	0.169	S	C	*	.	H	α-helix	trans	-64.9	-35.2	-177.3	170.2	0	0	0	0	111.5	S278 V279 P286	S278-V282 WeakPolarHBondContact O-CB 3.46Å; S278-V282 VanDerWaalsContact O-CG2 3.25Å; S278-V282 WeakPolarHBondContact O-CG2 3.37Å; S278-V282 PolarHBondContact O-N 3.42Å; V279-V282 PolarHBondContact O-N 3.01Å; V282-P286 WeakPolarHBondContact O-CD 3.49Å; V282-P286 VanDerWaalsContact O-CG 3.31Å; V282-P286 WeakPolarHBondContact O-CG 3.24Å
283	C	92.3	Very high	89.2	Confident	6 Å²	6	30.4 Å²	30.4	4%	0.041	19%	0.185	C	C	.	.	H	α-helix	trans	-78.4	-35.6	178.5	-71.7	0	0	0	0	113.1	V279 F280 T281 L316 K320	V279-C283 WeakPolarHBondContact O-CB 3.13Å; V279-C283 PolarHBondContact O-N 3.44Å; V279-C283 PolarHBondContact O-SG 3.06Å; F280-C283 PolarHBondContact O-N 2.99Å; T281-C283 VanDerWaalsContact C-N 3.28Å; T281-C283 PolarHBondContact O-N 3.46Å; C283-L316 WeakPolarHBondContact CB-O 3.38Å; C283-L316 PolarHBondContact SG-O 2.68Å; C283-K320 HydrophobicContact CB-CB 3.7Å
284	W	91.9	Very high	90.3	Very high	10 Å²	10	29.6 Å²	29.6	4%	0.038	18%	0.181	C	C	.	.	H	α-helix	trans	-95.3	-36.6	-173.8	-81.8	91.8	0	0	0	114.8	F118 V122 F208 F280 T281 P286 F287 T288 C317	F118-W284 HydrophobicContact CE1-CH2 4.22Å; F118-W284 AromaticContact CZ-CH2 3.84Å; F118-W284 HydrophobicContact CZ-CH2 3.84Å; F118-W284 HydrophobicContact CZ-CZ3 4.47Å; V122-W284 HydrophobicContact CB-CH2 3.75Å; V122-W284 HydrophobicContact CB-CZ2 3.98Å; V122-W284 HydrophobicContact CB-CZ3 4.43Å; V122-W284 HydrophobicContact CG1-CD2 4.36Å; V122-W284 HydrophobicContact CG1-CE3 4.03Å; V122-W284 HydrophobicContact CG1-CH2 3.12Å; V122-W284 HydrophobicContact CG1-CZ2 3.46Å; V122-W284 VanDerWaalsContact CG1-CZ2 3.46Å; V122-W284 HydrophobicContact CG1-CZ3 3.39Å; V122-W284 HydrophobicContact CG2-CH2 3.19Å; V122-W284 HydrophobicContact CG2-CZ2 3.41Å; V122-W284 VanDerWaalsContact CG2-CZ2 3.41Å; V122-W284 HydrophobicContact CG2-CZ3 4.24Å; F208-W284 HydrophobicContact CD2-CB 4.26Å; F208-W284 HydrophobicContact CE2-CB 3.91Å; F280-W284 AromaticContact CD2-CD1 3.53Å; F280-W284 HydrophobicContact CD2-CG 4.27Å; F280-W284 AromaticContact CE2-CD1 3.6Å; F280-W284 AromaticContact CE2-CG 3.99Å; F280-W284 HydrophobicContact CE2-CG 3.99Å; F280-W284 HydrophobicContact CZ-CG 4.36Å; F280-W284 VanDerWaalsContact O-CB 3.24Å; F280-W284 WeakPolarHBondContact O-CB 3.2Å; F280-W284 PolarHBondContact O-N 3.04Å; T281-W284 PolarHBondContact O-N 2.95Å; W284-P286 VanDerWaalsContact C-CD 3.48Å; W284-F287 HydrophobicContact CE3-CD1 4.04Å; W284-F287 HydrophobicContact CH2-CD1 4.44Å; W284-F287 AromaticContact CZ3-CD1 3.56Å; W284-F287 HydrophobicContact CZ3-CD1 3.56Å; W284-F287 AromaticContact CZ3-CE1 3.93Å; W284-F287 HydrophobicContact CZ3-CE1 3.93Å; W284-F287 HydrophobicContact CZ3-CG 4.42Å; W284-F287 PolarHBondContact O-N 3.18Å; W284-T288 PolarHBondContact O-N 3.34Å; W284-T288 PolarHBondContact O-OG1 3.33Å; W284-C317 HydrophobicContact CH2-CB 4.21Å; W284-C317 HydrophobicContact CZ2-CB 4.09Å
285	A	93.8	Very high	91.3	Very high	35 Å²	35	26.7 Å²	26.7	29%	0.289	17%	0.166	S	C	.	.	H	α-helix	trans	-56.3	-43	-177.2	0	0	0	0	0	113.2	F208 T281 F287 T288 A289	F208-A285 HydrophobicContact CE2-CB 4.3Å; F208-A285 HydrophobicContact CZ-CB 3.7Å; T281-A285 HydrophobicContact CG2-CB 4.42Å; T281-A285 WeakPolarHBondContact O-CB 3.31Å; T281-A285 PolarHBondContact O-N 3.5Å; A285-F287 VanDerWaalsContact C-N 3.32Å; A285-F287 PolarHBondContact O-N 3.36Å; A285-T288 PolarHBondContact O-N 2.87Å; A285-A289 WeakPolarHBondContact O-CB 3.48Å; A285-A289 PolarHBondContact O-N 3.22Å
286	P	95.3	Very high	91.9	Very high	44 Å²	44	28.3 Å²	28.3	29%	0.286	17%	0.171	S	C	.	.	H	α-helix	trans	-61.6	-39.8	176.1	-23.5	35.7	0	0	0	112.6	V282 W284 Y290 L313 L316	V282-P286 WeakPolarHBondContact O-CD 3.49Å; V282-P286 VanDerWaalsContact O-CG 3.31Å; V282-P286 WeakPolarHBondContact O-CG 3.24Å; W284-P286 VanDerWaalsContact C-CD 3.48Å; P286-Y290 VanDerWaalsContact O-CB 3.3Å; P286-Y290 WeakPolarHBondContact O-CB 3.13Å; P286-Y290 PolarHBondContact O-N 3.37Å; P286-L313 HydrophobicContact CB-CD2 3.52Å; P286-L316 HydrophobicContact CB-CD1 4.44Å; P286-L316 HydrophobicContact CG-CD1 4.35Å
287	F	93.5	Very high	92.5	Very high	3 Å²	3	30.2 Å²	30.2	1%	0.013	19%	0.185	C	C	.	.	H	α-helix	trans	-71.8	-36.8	179.8	-176.4	-94.8	0	0	0	112.7	F118 W119 V187 W284 A285 Y290 S291 L313 L314 C317	F118-F287 AromaticContact CE1-CE1 3.82Å; F118-F287 HydrophobicContact CE1-CE1 3.82Å; F118-F287 AromaticContact CE1-CZ 3.77Å; F118-F287 HydrophobicContact CE1-CZ 3.77Å; F118-F287 AromaticContact CZ-CE1 3.97Å; F118-F287 HydrophobicContact CZ-CE1 3.97Å; F118-F287 HydrophobicContact CZ-CE2 4.43Å; F118-F287 AromaticContact CZ-CZ 3.74Å; F118-F287 HydrophobicContact CZ-CZ 3.74Å; W119-F287 HydrophobicContact CH2-CD1 4.43Å; W119-F287 AromaticContact CH2-CE1 3.76Å; W119-F287 HydrophobicContact CH2-CE1 3.76Å; W119-F287 AromaticContact CZ2-CE1 3.85Å; W119-F287 HydrophobicContact CZ2-CE1 3.85Å; W119-F287 HydrophobicContact CZ2-CZ 4.5Å; V187-F287 HydrophobicContact CB-CZ 4.38Å; V187-F287 HydrophobicContact CG1-CE2 4.43Å; V187-F287 HydrophobicContact CG1-CZ 3.93Å; W284-F287 HydrophobicContact CE3-CD1 4.04Å; W284-F287 HydrophobicContact CH2-CD1 4.44Å; W284-F287 AromaticContact CZ3-CD1 3.56Å; W284-F287 HydrophobicContact CZ3-CD1 3.56Å; W284-F287 AromaticContact CZ3-CE1 3.93Å; W284-F287 HydrophobicContact CZ3-CE1 3.93Å; W284-F287 HydrophobicContact CZ3-CG 4.42Å; W284-F287 PolarHBondContact O-N 3.18Å; A285-F287 VanDerWaalsContact C-N 3.32Å; A285-F287 PolarHBondContact O-N 3.36Å; F287-Y290 HydrophobicContact CD2-CD1 4.15Å; F287-Y290 HydrophobicContact CE2-CD1 4.26Å; F287-Y290 HydrophobicContact CE2-CE1 4.26Å; F287-Y290 PolarHBondContact O-N 3.25Å; F287-S291 WeakPolarHBondContact O-CB 3.31Å; F287-S291 PolarHBondContact O-N 3.22Å; F287-S291 PolarHBondContact O-OG 3.04Å; F287-L313 HydrophobicContact CD2-CB 4.42Å; F287-L314 HydrophobicContact CE2-CD1 4.5Å; F287-C317 WeakPolarHBondContact CB-SG 3.4Å; F287-C317 VanDerWaalsContact CD2-SG 3.58Å; F287-C317 WeakPolarHBondContact CG-SG 3.11Å
288	T	94.3	Very high	93	Very high	3 Å²	3	34.6 Å²	34.6	2%	0.018	20%	0.204	C	C	.	.	H	α-helix	trans	-61.9	-48.8	172	-61.9	0	0	0	0	110.9	M204 F208 F209 W284 A285 Y290 S291 L292	M204-T288 HydrophobicContact CB-CG2 4.42Å; M204-T288 HydrophobicContact CG-CG2 4.36Å; M204-T288 HydrophobicContact SD-CG2 3.72Å; F208-T288 HydrophobicContact CB-CG2 4.37Å; F208-T288 HydrophobicContact CD1-CG2 3.56Å; F208-T288 VanDerWaalsContact CD2-OG1 3.29Å; F208-T288 WeakPolarHBondContact CD2-OG1 3.35Å; F208-T288 HydrophobicContact CE1-CG2 3.94Å; F208-T288 HydrophobicContact CG-CG2 3.91Å; F208-T288 WeakPolarHBondContact CG-OG1 3.31Å; F209-T288 HydrophobicContact CE2-CG2 4.17Å; F209-T288 HydrophobicContact CZ-CG2 4.17Å; W284-T288 PolarHBondContact O-N 3.34Å; W284-T288 PolarHBondContact O-OG1 3.33Å; A285-T288 PolarHBondContact O-N 2.87Å; T288-Y290 VanDerWaalsContact C-N 3.33Å; T288-Y290 PolarHBondContact O-N 2.72Å; T288-S291 PolarHBondContact O-N 3.48Å; T288-L292 HydrophobicContact CG2-CD1 4.32Å; T288-L292 WeakPolarHBondContact O-CG 3.3Å; T288-L292 PolarHBondContact O-N 2.89Å
289	A	95.3	Very high	93.3	Very high	54 Å²	54	34.2 Å²	34.2	45%	0.446	21%	0.208	S	C	.	.	H	α-helix	trans	-59.5	-45.6	176.8	0	0	0	0	0	111.3	A285 S291 L292 V293	A285-A289 WeakPolarHBondContact O-CB 3.48Å; A285-A289 PolarHBondContact O-N 3.22Å; A289-S291 PolarHBondContact O-N 3.45Å; A289-L292 PolarHBondContact O-N 3.03Å; A289-V293 VanDerWaalsContact O-CG2 3.31Å; A289-V293 WeakPolarHBondContact O-CG2 3.45Å; A289-V293 PolarHBondContact O-N 2.74Å
290	Y	94.9	Very high	93.5	Very high	10 Å²	10	34.8 Å²	34.8	4%	0.039	21%	0.209	C	C	.	.	H	α-helix	trans	-59.5	-42.9	174.6	158.1	-91.6	0	0	0	113.2	V187 P286 F287 T288 L292 V293 T294 F300 F306 I309 S310 L313	V187-Y290 HydrophobicContact CG2-CE1 4.48Å; P286-Y290 VanDerWaalsContact O-CB 3.3Å; P286-Y290 WeakPolarHBondContact O-CB 3.13Å; P286-Y290 PolarHBondContact O-N 3.37Å; F287-Y290 HydrophobicContact CD2-CD1 4.15Å; F287-Y290 HydrophobicContact CE2-CD1 4.26Å; F287-Y290 HydrophobicContact CE2-CE1 4.26Å; F287-Y290 PolarHBondContact O-N 3.25Å; T288-Y290 VanDerWaalsContact C-N 3.33Å; T288-Y290 PolarHBondContact O-N 2.72Å; Y290-L292 VanDerWaalsContact C-N 3.31Å; Y290-L292 PolarHBondContact O-N 3.35Å; Y290-V293 PolarHBondContact O-N 3.29Å; Y290-T294 WeakPolarHBondContact CE2-OG1 3.45Å; Y290-T294 WeakPolarHBondContact O-CB 3.31Å; Y290-T294 PolarHBondContact O-N 2.8Å; Y290-T294 PolarHBondContact O-OG1 3.34Å; Y290-F300 AromaticContact CD2-CE1 3.7Å; Y290-F300 HydrophobicContact CD2-CE1 3.7Å; Y290-F300 AromaticContact CD2-CZ 3.98Å; Y290-F300 HydrophobicContact CD2-CZ 3.98Å; Y290-F300 AromaticContact CE2-CE1 3.87Å; Y290-F300 HydrophobicContact CE2-CE1 3.87Å; Y290-F300 HydrophobicContact CE2-CZ 4.35Å; Y290-F306 HydrophobicContact CE2-CD2 4.45Å; Y290-F306 AromaticContact CE2-CE2 3.69Å; Y290-F306 HydrophobicContact CE2-CE2 3.69Å; Y290-F306 AromaticContact CE2-CZ 3.97Å; Y290-F306 HydrophobicContact CE2-CZ 3.97Å; Y290-F306 AromaticContact CZ-CZ 3.82Å; Y290-F306 WeakPolarHBondContact OH-CZ 3.46Å; Y290-I309 HydrophobicContact CD2-CG2 4.47Å; Y290-S310 WeakPolarHBondContact CE2-OG 3.05Å; Y290-S310 WeakPolarHBondContact OH-CB 3.34Å; Y290-S310 PolarHBondContact OH-OG 3.46Å; Y290-L313 HydrophobicContact CD1-CD1 4.19Å; Y290-L313 HydrophobicContact CD2-CD1 3.35Å; Y290-L313 HydrophobicContact CE2-CD1 4.18Å; Y290-L313 HydrophobicContact CG-CD1 3.36Å
291	S	94	Very high	93.8	Very high	0 Å²	0	35 Å²	35	0%	0	21%	0.21	C	C	.	.	H	α-helix	trans	-64.6	-39.2	-179.7	-62.9	0	0	0	0	111.1	F287 T288 A289 T295	F287-S291 WeakPolarHBondContact O-CB 3.31Å; F287-S291 PolarHBondContact O-N 3.22Å; F287-S291 PolarHBondContact O-OG 3.04Å; T288-S291 PolarHBondContact O-N 3.48Å; A289-S291 PolarHBondContact O-N 3.45Å; S291-T295 WeakPolarHBondContact O-CB 3.36Å; S291-T295 PolarHBondContact O-N 3.46Å; S291-T295 PolarHBondContact O-OG1 2.82Å
292	L	96.2	Very high	93.9	Very high	33 Å²	33	37.5 Å²	37.5	17%	0.173	22%	0.219	C	C	.	.	H	α-helix	trans	-65.5	-54.1	173.7	-69.2	170.3	0	0	0	111	V200 L201 M204 F209 T288 A289 Y290 T294 T295 F296	V200-L292 HydrophobicContact CG1-CD2 4.44Å; L201-L292 HydrophobicContact CD2-CD2 3.85Å; M204-L292 HydrophobicContact CB-CD2 4.43Å; M204-L292 HydrophobicContact CG-CD2 4.04Å; M204-L292 HydrophobicContact CG-CG 4.35Å; F209-L292 HydrophobicContact CE2-CD1 4.04Å; F209-L292 HydrophobicContact CZ-CD1 4Å; T288-L292 HydrophobicContact CG2-CD1 4.32Å; T288-L292 WeakPolarHBondContact O-CG 3.3Å; T288-L292 PolarHBondContact O-N 2.89Å; A289-L292 PolarHBondContact O-N 3.03Å; Y290-L292 VanDerWaalsContact C-N 3.31Å; Y290-L292 PolarHBondContact O-N 3.35Å; L292-T294 VanDerWaalsContact C-N 3.25Å; L292-T294 PolarHBondContact O-N 3.27Å; L292-T295 WeakPolarHBondContact O-CB 3.48Å; L292-T295 PolarHBondContact O-N 2.83Å; L292-F296 HydrophobicContact CD2-CE2 4.15Å; L292-F296 WeakPolarHBondContact O-CD2 3.48Å; L292-F296 PolarHBondContact O-N 3.43Å; L292-F296 VanDerWaalsContact O-N 3.09Å
293	V	95.6	Very high	93.9	Very high	68 Å²	68	38.4 Å²	38.4	41%	0.412	22%	0.215	S	C	.	.	H	α-helix	trans	-57.3	-42.4	179.7	173.6	0	0	0	0	110.9	A289 Y290 T295 F296 S297 F300	A289-V293 VanDerWaalsContact O-CG2 3.31Å; A289-V293 WeakPolarHBondContact O-CG2 3.45Å; A289-V293 PolarHBondContact O-N 2.74Å; Y290-V293 PolarHBondContact O-N 3.29Å; V293-T295 VanDerWaalsContact C-N 3.33Å; V293-T295 PolarHBondContact O-N 3.4Å; V293-F296 PolarHBondContact O-N 2.92Å; V293-S297 WeakPolarHBondContact O-CA 3.5Å; V293-S297 WeakPolarHBondContact O-CB 3.12Å; V293-S297 PolarHBondContact O-N 3.41Å; V293-F300 HydrophobicContact CG1-CB 3.9Å; V293-F300 HydrophobicContact CG1-CD1 3.71Å; V293-F300 HydrophobicContact CG1-CD2 4.07Å; V293-F300 HydrophobicContact CG1-CE1 4.22Å; V293-F300 HydrophobicContact CG1-CG 3.62Å
294	T	93.9	Very high	93.8	Very high	0 Å²	0	44.7 Å²	44.7	0%	0	25%	0.248	C	C	.	.	H	α-helix	trans	-61.6	-40.5	176.8	-65.4	0	0	0	0	112.4	F188 Y190 Y290 L292 F300 Y301 F306	F188-T294 WeakPolarHBondContact O-CG2 3.47Å; Y190-T294 VanDerWaalsContact CA-O 3.24Å; Y190-T294 WeakPolarHBondContact CA-O 3.41Å; Y190-T294 WeakPolarHBondContact CB-O 3.41Å; Y190-T294 PolarHBondContact N-O 3.45Å; Y290-T294 WeakPolarHBondContact CE2-OG1 3.45Å; Y290-T294 WeakPolarHBondContact O-CB 3.31Å; Y290-T294 PolarHBondContact O-N 2.8Å; Y290-T294 PolarHBondContact O-OG1 3.34Å; L292-T294 VanDerWaalsContact C-N 3.25Å; L292-T294 PolarHBondContact O-N 3.27Å; T294-F300 WeakPolarHBondContact OG1-CE1 3.39Å; T294-Y301 HydrophobicContact CG2-CD2 3.53Å; T294-Y301 HydrophobicContact CG2-CE2 4.01Å; T294-Y301 HydrophobicContact CG2-CG 4.47Å; T294-F306 HydrophobicContact CG2-CE2 3.99Å; T294-F306 HydrophobicContact CG2-CZ 3.9Å
295	T	94.9	Very high	93.7	Very high	0 Å²	0	47.2 Å²	47.2	0%	0	27%	0.267	C	S	.	.	H	α-helix	trans	-67.4	-39.9	-179.2	-63.9	0	0	0	0	112	Y196 H197 V200 S291 L292 V293	Y196-T295 HydrophobicContact CD1-CG2 3.92Å; Y196-T295 HydrophobicContact CE1-CG2 3.72Å; H197-T295 VanDerWaalsContact CD2-CG2 3.47Å; H197-T295 WeakPolarHBondContact CD2-CG2 3.32Å; H197-T295 PolarHBondContact NE2-O 3.48Å; V200-T295 HydrophobicContact CB-CG2 4.3Å; V200-T295 HydrophobicContact CG1-CG2 4.34Å; V200-T295 HydrophobicContact CG2-CG2 4.24Å; S291-T295 WeakPolarHBondContact O-CB 3.36Å; S291-T295 PolarHBondContact O-N 3.46Å; S291-T295 PolarHBondContact O-OG1 2.82Å; L292-T295 WeakPolarHBondContact O-CB 3.48Å; L292-T295 PolarHBondContact O-N 2.83Å; V293-T295 VanDerWaalsContact C-N 3.33Å; V293-T295 PolarHBondContact O-N 3.4Å
296	F	95.2	Very high	93.6	Very high	94 Å²	94	45.7 Å²	45.7	41%	0.412	25%	0.254	S	S	.	.	H	α-helix	trans	-98.3	-23.5	-172.6	-66.8	-73.9	0	0	0	114.6	H197 L201 L292 V293	H197-F296 HydrophobicContact CB-CE1 3.84Å; H197-F296 HydrophobicContact CB-CZ 4.08Å; H197-F296 AromaticContact CD2-CE1 3.96Å; H197-F296 AromaticContact CE1-CD1 3.89Å; H197-F296 AromaticContact CE1-CE1 3.94Å; H197-F296 AromaticContact CG-CE1 3.51Å; H197-F296 AromaticContact ND1-CD1 3.91Å; H197-F296 AromaticContact ND1-CE1 3.5Å; L201-F296 HydrophobicContact CD1-CZ 3.88Å; L201-F296 HydrophobicContact CD2-CE2 3.97Å; L201-F296 HydrophobicContact CD2-CZ 3.95Å; L201-F296 HydrophobicContact CG-CE2 4.29Å; L201-F296 HydrophobicContact CG-CZ 3.84Å; L292-F296 HydrophobicContact CD2-CE2 4.15Å; L292-F296 WeakPolarHBondContact O-CD2 3.48Å; L292-F296 PolarHBondContact O-N 3.43Å; L292-F296 VanDerWaalsContact O-N 3.09Å; V293-F296 PolarHBondContact O-N 2.92Å
297	S	94.9	Very high	93.5	Very high	46 Å²	46	45.2 Å²	45.2	32%	0.322	25%	0.248	S	C	.	.			trans	-107	102.7	-174	-173.2	0	0	0	0	112.3	V293 G299 F300 Y301	V293-S297 WeakPolarHBondContact O-CA 3.5Å; V293-S297 WeakPolarHBondContact O-CB 3.12Å; V293-S297 PolarHBondContact O-N 3.41Å; S297-G299 VanDerWaalsContact C-N 3.27Å; S297-G299 PolarHBondContact O-N 2.83Å; S297-F300 PolarHBondContact O-N 3.43Å; S297-F300 PolarHBondContact OG-N 3.09Å; S297-Y301 PolarHBondContact O-N 2.9Å
298	F	93	Very high	93.5	Very high	114 Å²	114	48.3 Å²	48.3	50%	0.5	26%	0.262	S	S	.	.	H	α-helix	trans	-55.2	-44.9	171.5	178.8	-93.9	0	0	0	111.6	Y190 F300 Y301 H302	Y190-F298 AromaticContact CD1-CD2 3.8Å; Y190-F298 HydrophobicContact CD1-CD2 3.8Å; Y190-F298 HydrophobicContact CD2-CB 4.1Å; Y190-F298 HydrophobicContact CE1-CB 4.21Å; Y190-F298 AromaticContact CE1-CD2 3.54Å; Y190-F298 HydrophobicContact CE1-CD2 3.54Å; Y190-F298 HydrophobicContact CE1-CE2 4.44Å; Y190-F298 HydrophobicContact CE1-CG 4.36Å; Y190-F298 HydrophobicContact CE2-CB 3.73Å; Y190-F298 HydrophobicContact CG-CB 4.47Å; Y190-F298 HydrophobicContact CG-CD2 4.43Å; Y190-F298 AromaticContact CZ-CD2 3.95Å; F298-F300 PolarHBondContact O-N 2.99Å; F298-Y301 PolarHBondContact O-N 2.89Å; F298-H302 AromaticContact CD2-CE1 3.32Å; F298-H302 WeakPolarHBondContact CD2-CE1 3.45Å; F298-H302 AromaticContact CD2-ND1 3.48Å; F298-H302 WeakPolarHBondContact CD2-ND1 3.36Å; F298-H302 AromaticContact CE1-ND1 3.9Å; F298-H302 AromaticContact CE2-CE1 3.04Å; F298-H302 WeakPolarHBondContact CE2-CE1 3.43Å; F298-H302 AromaticContact CE2-ND1 3.38Å; F298-H302 WeakPolarHBondContact CE2-ND1 3.47Å; F298-H302 AromaticContact CE2-NE2 3.74Å; F298-H302 AromaticContact CG-ND1 3.81Å; F298-H302 AromaticContact CZ-CE1 3.62Å; F298-H302 AromaticContact CZ-ND1 3.59Å; F298-H302 PolarHBondContact O-N 3.35Å; F298-H302 PolarHBondContact O-ND1 3.46Å
299	G	93.1	Very high	93.4	Very high	44 Å²	44	50.9 Å²	50.9	45%	0.454	28%	0.275	S	S	.	.	H	α-helix	trans	-64.1	-37.4	-178.1	0	0	0	0	0	112.9	S297 K303	S297-G299 VanDerWaalsContact C-N 3.27Å; S297-G299 PolarHBondContact O-N 2.83Å; G299-K303 WeakPolarHBondContact O-CG 3.37Å
300	F	93.6	Very high	93.4	Very high	37 Å²	37	48.5 Å²	48.5	16%	0.162	26%	0.255	C	S	.	.	H	α-helix	trans	-69.3	-43.5	175.9	-178.5	-99.8	0	0	0	112.3	Y290 V293 T294 S297 F298 H302 K303 F306 I309	Y290-F300 AromaticContact CD2-CE1 3.7Å; Y290-F300 HydrophobicContact CD2-CE1 3.7Å; Y290-F300 AromaticContact CD2-CZ 3.98Å; Y290-F300 HydrophobicContact CD2-CZ 3.98Å; Y290-F300 AromaticContact CE2-CE1 3.87Å; Y290-F300 HydrophobicContact CE2-CE1 3.87Å; Y290-F300 HydrophobicContact CE2-CZ 4.35Å; V293-F300 HydrophobicContact CG1-CB 3.9Å; V293-F300 HydrophobicContact CG1-CD1 3.71Å; V293-F300 HydrophobicContact CG1-CD2 4.07Å; V293-F300 HydrophobicContact CG1-CE1 4.22Å; V293-F300 HydrophobicContact CG1-CG 3.62Å; T294-F300 WeakPolarHBondContact OG1-CE1 3.39Å; S297-F300 PolarHBondContact O-N 3.43Å; S297-F300 PolarHBondContact OG-N 3.09Å; F298-F300 PolarHBondContact O-N 2.99Å; F300-H302 VanDerWaalsContact C-N 3.3Å; F300-H302 PolarHBondContact O-N 2.96Å; F300-K303 PolarHBondContact O-N 3.28Å; F300-F306 HydrophobicContact CD1-CD2 4.11Å; F300-F306 HydrophobicContact CD1-CE2 4.06Å; F300-F306 AromaticContact CE1-CD2 3.94Å; F300-F306 HydrophobicContact CE1-CD2 3.94Å; F300-F306 AromaticContact CE1-CE2 3.84Å; F300-F306 HydrophobicContact CE1-CE2 3.84Å; F300-I309 HydrophobicContact CE2-CD1 4.31Å; F300-I309 HydrophobicContact CZ-CG2 4.08Å
301	Y	92.8	Very high	93.3	Very high	12 Å²	12	48 Å²	48	5%	0.047	25%	0.253	C	S	.	.	H	α-helix	trans	-64.3	-31.7	-176.7	-173.2	-114.4	0	0	0	113.7	Q178 R182 T294 S297 F298 F306	Q178-Y301 VanDerWaalsContact CB-OH 3.29Å; Q178-Y301 WeakPolarHBondContact CB-OH 3.43Å; Q178-Y301 HydrophobicContact CG-CE1 4.33Å; R182-Y301 HydrophobicContact CB-CE2 4.25Å; R182-Y301 HydrophobicContact CG-CE1 4.31Å; R182-Y301 PolarHBondContact NE-O 3.01Å; T294-Y301 HydrophobicContact CG2-CD2 3.53Å; T294-Y301 HydrophobicContact CG2-CE2 4.01Å; T294-Y301 HydrophobicContact CG2-CG 4.47Å; S297-Y301 PolarHBondContact O-N 2.9Å; F298-Y301 PolarHBondContact O-N 2.89Å; Y301-F306 HydrophobicContact CD2-CD2 4.32Å; Y301-F306 AromaticContact CD2-CE1 3.86Å; Y301-F306 HydrophobicContact CD2-CE1 3.86Å; Y301-F306 AromaticContact CD2-CE2 3.63Å; Y301-F306 HydrophobicContact CD2-CE2 3.63Å; Y301-F306 AromaticContact CD2-CZ 3.36Å; Y301-F306 HydrophobicContact CD2-CZ 3.36Å; Y301-F306 AromaticContact CE2-CE1 3.79Å; Y301-F306 HydrophobicContact CE2-CE1 3.79Å; Y301-F306 HydrophobicContact CE2-CE2 4.33Å; Y301-F306 AromaticContact CE2-CZ 3.59Å; Y301-F306 HydrophobicContact CE2-CZ 3.59Å; Y301-F306 WeakPolarHBondContact O-CG 3.21Å
302	H	91.8	Very high	93.3	Very high	76 Å²	76	53.3 Å²	53.3	35%	0.352	27%	0.273	S	S	.	.	T	Hydrogen-bonded Turn	trans	-94.8	2.7	-177.3	-65.1	87.7	0	0	0	114.4	F298 F300	F298-H302 AromaticContact CD2-CE1 3.32Å; F298-H302 WeakPolarHBondContact CD2-CE1 3.45Å; F298-H302 AromaticContact CD2-ND1 3.48Å; F298-H302 WeakPolarHBondContact CD2-ND1 3.36Å; F298-H302 AromaticContact CE1-ND1 3.9Å; F298-H302 AromaticContact CE2-CE1 3.04Å; F298-H302 WeakPolarHBondContact CE2-CE1 3.43Å; F298-H302 AromaticContact CE2-ND1 3.38Å; F298-H302 WeakPolarHBondContact CE2-ND1 3.47Å; F298-H302 AromaticContact CE2-NE2 3.74Å; F298-H302 AromaticContact CG-ND1 3.81Å; F298-H302 AromaticContact CZ-CE1 3.62Å; F298-H302 AromaticContact CZ-ND1 3.59Å; F298-H302 PolarHBondContact O-N 3.35Å; F298-H302 PolarHBondContact O-ND1 3.46Å; F300-H302 VanDerWaalsContact C-N 3.3Å; F300-H302 PolarHBondContact O-N 2.96Å
303	K	92.3	Very high	93.2	Very high	117 Å²	117	53 Å²	53	51%	0.509	27%	0.272	S	S	.	.			trans	-61.2	145.4	172.6	-80.1	174.9	-177.1	-171.4	0	111.4	G299 F300 S305 F306	G299-K303 WeakPolarHBondContact O-CG 3.37Å; F300-K303 PolarHBondContact O-N 3.28Å; K303-S305 VanDerWaalsContact C-N 3.28Å; K303-S305 PolarHBondContact O-N 3.04Å; K303-F306 WeakPolarHBondContact O-CB 3.5Å; K303-F306 PolarHBondContact O-N 3.31Å; K303-F306 VanDerWaalsContact O-N 3.07Å
304	D	88.7	Confident	93.1	Very high	138 Å²	138	50 Å²	50	74%	0.738	25%	0.253	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.7	-36.8	175.6	-60.4	-39.4	0	0	0	111.7	F306	D304-F306 PolarHBondContact O-N 3.48Å
305	S	90.5	Very high	93	Very high	63 Å²	63	50.6 Å²	50.6	44%	0.441	26%	0.256	S	S	.	.	T	Hydrogen-bonded Turn	trans	-73.7	0.1	176.2	-44.9	0	0	0	0	114.3	K303 F307 Q308 I309	K303-S305 VanDerWaalsContact C-N 3.28Å; K303-S305 PolarHBondContact O-N 3.04Å; S305-F307 PolarHBondContact O-N 3.37Å; S305-Q308 PolarHBondContact O-N 2.8Å; S305-I309 WeakPolarHBondContact O-CG1 3.35Å; S305-I309 PolarHBondContact O-N 3.37Å
306	F	92.8	Very high	92.9	Very high	3 Å²	3	53.6 Å²	53.6	1%	0.013	27%	0.271	C	S	.	.	H	α-helix	trans	-59.4	-44.8	-175.4	179.4	-93.8	0	0	0	112.1	R182 A183 Y290 T294 F300 Y301 K303 D304 Q308 I309 S310	R182-F306 HydrophobicContact CB-CD1 3.61Å; R182-F306 HydrophobicContact CB-CE1 3.64Å; R182-F306 VanDerWaalsContact O-CD1 3.26Å; R182-F306 WeakPolarHBondContact O-CD1 3.22Å; R182-F306 WeakPolarHBondContact O-CE1 3.12Å; A183-F306 HydrophobicContact CB-CE1 4.31Å; Y290-F306 HydrophobicContact CE2-CD2 4.45Å; Y290-F306 AromaticContact CE2-CE2 3.69Å; Y290-F306 HydrophobicContact CE2-CE2 3.69Å; Y290-F306 AromaticContact CE2-CZ 3.97Å; Y290-F306 HydrophobicContact CE2-CZ 3.97Å; Y290-F306 AromaticContact CZ-CZ 3.82Å; Y290-F306 WeakPolarHBondContact OH-CZ 3.46Å; T294-F306 HydrophobicContact CG2-CE2 3.99Å; T294-F306 HydrophobicContact CG2-CZ 3.9Å; F300-F306 HydrophobicContact CD1-CD2 4.11Å; F300-F306 HydrophobicContact CD1-CE2 4.06Å; F300-F306 AromaticContact CE1-CD2 3.94Å; F300-F306 HydrophobicContact CE1-CD2 3.94Å; F300-F306 AromaticContact CE1-CE2 3.84Å; F300-F306 HydrophobicContact CE1-CE2 3.84Å; Y301-F306 HydrophobicContact CD2-CD2 4.32Å; Y301-F306 AromaticContact CD2-CE1 3.86Å; Y301-F306 HydrophobicContact CD2-CE1 3.86Å; Y301-F306 AromaticContact CD2-CE2 3.63Å; Y301-F306 HydrophobicContact CD2-CE2 3.63Å; Y301-F306 AromaticContact CD2-CZ 3.36Å; Y301-F306 HydrophobicContact CD2-CZ 3.36Å; Y301-F306 AromaticContact CE2-CE1 3.79Å; Y301-F306 HydrophobicContact CE2-CE1 3.79Å; Y301-F306 HydrophobicContact CE2-CE2 4.33Å; Y301-F306 AromaticContact CE2-CZ 3.59Å; Y301-F306 HydrophobicContact CE2-CZ 3.59Å; Y301-F306 WeakPolarHBondContact O-CG 3.21Å; K303-F306 WeakPolarHBondContact O-CB 3.5Å; K303-F306 PolarHBondContact O-N 3.31Å; K303-F306 VanDerWaalsContact O-N 3.07Å; D304-F306 PolarHBondContact O-N 3.48Å; F306-Q308 VanDerWaalsContact C-N 3.33Å; F306-Q308 PolarHBondContact O-N 2.98Å; F306-I309 PolarHBondContact O-N 3.42Å; F306-S310 WeakPolarHBondContact CE1-OG 3.46Å; F306-S310 VanDerWaalsContact O-CB 3.28Å; F306-S310 WeakPolarHBondContact O-CB 3.28Å; F306-S310 PolarHBondContact O-N 3.31Å; F306-S310 PolarHBondContact O-OG 2.93Å
307	F	92.3	Very high	92.8	Very high	35 Å²	35	49.1 Å²	49.1	15%	0.154	25%	0.252	C	S	.	.	H	α-helix	trans	-61.5	-42.2	179.1	-174.1	-90.6	0	0	0	111.8	T98 R182 P184 S305 S310 T311	T98-F307 HydrophobicContact CG2-CE2 4.47Å; R182-F307 WeakPolarHBondContact O-CD2 3.33Å; P184-F307 HydrophobicContact CB-CZ 4.43Å; P184-F307 HydrophobicContact CG-CE1 4.3Å; P184-F307 HydrophobicContact CG-CE2 3.99Å; P184-F307 HydrophobicContact CG-CZ 3.84Å; S305-F307 PolarHBondContact O-N 3.37Å; F307-S310 PolarHBondContact O-N 2.89Å; F307-T311 PolarHBondContact O-N 3.38Å; F307-T311 PolarHBondContact O-OG1 2.99Å
308	Q	93.1	Very high	92.8	Very high	68 Å²	68	47 Å²	47	32%	0.318	24%	0.237	S	C	.	.	H	α-helix	trans	-64.6	-47.7	177.7	-175.1	-175.3	-0.4	0	0	111.8	L33 L37 F41 S305 F306 S310 T311 W312	L33-Q308 HydrophobicContact CD1-CB 4.02Å; L33-Q308 HydrophobicContact CD1-CG 4.08Å; L37-Q308 HydrophobicContact CD2-CG 4.21Å; F41-Q308 HydrophobicContact CE2-CG 4.05Å; F41-Q308 HydrophobicContact CZ-CG 3.98Å; S305-Q308 PolarHBondContact O-N 2.8Å; F306-Q308 VanDerWaalsContact C-N 3.33Å; F306-Q308 PolarHBondContact O-N 2.98Å; Q308-S310 VanDerWaalsContact C-N 3.33Å; Q308-S310 PolarHBondContact O-N 3.45Å; Q308-T311 WeakPolarHBondContact O-CB 3.26Å; Q308-T311 PolarHBondContact O-N 3.48Å; Q308-W312 VanDerWaalsContact O-CD1 3.28Å; Q308-W312 PolarHBondContact O-N 3.43Å; Q308-W312 VanDerWaalsContact O-N 3.13Å
309	I	93.3	Very high	92.8	Very high	57 Å²	57	44.5 Å²	44.5	29%	0.292	23%	0.228	S	C	.	.	H	α-helix	trans	-61.1	-44.5	177.3	-66.4	165.5	0	0	0	110.4	Y290 F300 S305 F306 T311 W312 L313	Y290-I309 HydrophobicContact CD2-CG2 4.47Å; F300-I309 HydrophobicContact CE2-CD1 4.31Å; F300-I309 HydrophobicContact CZ-CG2 4.08Å; S305-I309 WeakPolarHBondContact O-CG1 3.35Å; S305-I309 PolarHBondContact O-N 3.37Å; F306-I309 PolarHBondContact O-N 3.42Å; I309-T311 VanDerWaalsContact C-N 3.27Å; I309-T311 PolarHBondContact O-N 3.44Å; I309-W312 PolarHBondContact O-N 3.22Å; I309-L313 HydrophobicContact CG2-CD1 3.76Å; I309-L313 HydrophobicContact CG2-CG 4.48Å; I309-L313 WeakPolarHBondContact O-CG 3.46Å; I309-L313 PolarHBondContact O-N 2.91Å; I309-L313 VanDerWaalsContact O-N 3.12Å
310	S	93.8	Very high	92.8	Very high	3 Å²	3	42.7 Å²	42.7	2%	0.021	21%	0.208	C	C	.	.	H	α-helix	trans	-59.7	-39.1	177.4	-54.3	0	0	0	0	111.6	Y290 F306 F307 Q308 L314	Y290-S310 WeakPolarHBondContact CE2-OG 3.05Å; Y290-S310 WeakPolarHBondContact OH-CB 3.34Å; Y290-S310 PolarHBondContact OH-OG 3.46Å; F306-S310 WeakPolarHBondContact CE1-OG 3.46Å; F306-S310 VanDerWaalsContact O-CB 3.28Å; F306-S310 WeakPolarHBondContact O-CB 3.28Å; F306-S310 PolarHBondContact O-N 3.31Å; F306-S310 PolarHBondContact O-OG 2.93Å; F307-S310 PolarHBondContact O-N 2.89Å; Q308-S310 VanDerWaalsContact C-N 3.33Å; Q308-S310 PolarHBondContact O-N 3.45Å; S310-L314 WeakPolarHBondContact O-CB 3.36Å; S310-L314 PolarHBondContact O-N 2.9Å
311	T	93.8	Very high	92.8	Very high	0 Å²	0	40.9 Å²	40.9	0%	0	20%	0.2	C	C	.	.	H	α-helix	trans	-64.7	-47.5	178.1	-53.6	0	0	0	0	111.7	F41 V99 P184 F307 Q308 I309 L313 L314 W315	F41-T311 HydrophobicContact CB-CG2 4.37Å; F41-T311 HydrophobicContact CD2-CG2 3.41Å; F41-T311 VanDerWaalsContact CD2-CG2 3.41Å; F41-T311 HydrophobicContact CE2-CG2 3.71Å; F41-T311 HydrophobicContact CG-CG2 3.93Å; F41-T311 HydrophobicContact CZ-CG2 4.39Å; V99-T311 HydrophobicContact CG2-CG2 4Å; P184-T311 HydrophobicContact CG-CG2 4.3Å; P184-T311 WeakPolarHBondContact CG-OG1 3.38Å; F307-T311 PolarHBondContact O-N 3.38Å; F307-T311 PolarHBondContact O-OG1 2.99Å; Q308-T311 WeakPolarHBondContact O-CB 3.26Å; Q308-T311 PolarHBondContact O-N 3.48Å; I309-T311 VanDerWaalsContact C-N 3.27Å; I309-T311 PolarHBondContact O-N 3.44Å; T311-L313 VanDerWaalsContact C-N 3.34Å; T311-L313 PolarHBondContact O-N 2.94Å; T311-L314 PolarHBondContact O-N 3.2Å; T311-W315 HydrophobicContact CG2-CZ2 4.11Å; T311-W315 VanDerWaalsContact O-CD1 3.25Å; T311-W315 VanDerWaalsContact O-CG 3.28Å; T311-W315 PolarHBondContact O-N 3.4Å
312	W	94.3	Very high	92.9	Very high	112 Å²	112	40.5 Å²	40.5	42%	0.424	20%	0.199	S	C	.	.	H	α-helix	trans	-58.3	-44.5	177.1	-80.2	117.8	0	0	0	112.8	F40 F41 Q308 I309 W315 L316	F40-W312 AromaticContact CE1-CH2 3.65Å; F40-W312 HydrophobicContact CE1-CH2 3.65Å; F40-W312 HydrophobicContact CE1-CZ2 4.17Å; F40-W312 HydrophobicContact CE1-CZ3 4.4Å; F40-W312 HydrophobicContact CZ-CH2 4.2Å; F41-W312 HydrophobicContact CE1-CD2 4.14Å; F41-W312 AromaticContact CE1-CE2 3.61Å; F41-W312 HydrophobicContact CE1-CH2 4.25Å; F41-W312 AromaticContact CE1-CZ2 3.67Å; F41-W312 HydrophobicContact CE1-CZ2 3.67Å; F41-W312 AromaticContact CE1-NE1 3.9Å; F41-W312 AromaticContact CZ-CD1 3.9Å; F41-W312 HydrophobicContact CZ-CD2 4.24Å; F41-W312 AromaticContact CZ-CE2 3.72Å; F41-W312 HydrophobicContact CZ-CG 4.35Å; F41-W312 HydrophobicContact CZ-CZ2 4.19Å; F41-W312 AromaticContact CZ-NE1 3.5Å; Q308-W312 VanDerWaalsContact O-CD1 3.28Å; Q308-W312 PolarHBondContact O-N 3.43Å; Q308-W312 VanDerWaalsContact O-N 3.13Å; I309-W312 PolarHBondContact O-N 3.22Å; W312-W315 HydrophobicContact CD2-CE3 4.38Å; W312-W315 HydrophobicContact CD2-CZ3 4.44Å; W312-W315 AromaticContact CE3-CE3 3.51Å; W312-W315 HydrophobicContact CE3-CE3 3.51Å; W312-W315 AromaticContact CE3-CZ3 3.68Å; W312-W315 HydrophobicContact CE3-CZ3 3.68Å; W312-W315 AromaticContact CH2-CZ3 3.95Å; W312-W315 HydrophobicContact CH2-CZ3 3.95Å; W312-W315 AromaticContact CZ3-CE3 3.65Å; W312-W315 HydrophobicContact CZ3-CE3 3.65Å; W312-W315 AromaticContact CZ3-CZ3 3.4Å; W312-W315 HydrophobicContact CZ3-CZ3 3.4Å; W312-W315 WeakPolarHBondContact O-CB 3.32Å; W312-W315 PolarHBondContact O-N 3.46Å; W312-L316 PolarHBondContact O-N 3.33Å
313	L	94.4	Very high	93	Very high	27 Å²	27	39.2 Å²	39.2	14%	0.141	20%	0.195	C	C	.	.	H	α-helix	trans	-72	-36.6	-178.1	-66.3	167.6	0	0	0	112.2	P286 F287 Y290 I309 T311 W315 L316 C317	P286-L313 HydrophobicContact CB-CD2 3.52Å; F287-L313 HydrophobicContact CD2-CB 4.42Å; Y290-L313 HydrophobicContact CD1-CD1 4.19Å; Y290-L313 HydrophobicContact CD2-CD1 3.35Å; Y290-L313 HydrophobicContact CE2-CD1 4.18Å; Y290-L313 HydrophobicContact CG-CD1 3.36Å; I309-L313 HydrophobicContact CG2-CD1 3.76Å; I309-L313 HydrophobicContact CG2-CG 4.48Å; I309-L313 WeakPolarHBondContact O-CG 3.46Å; I309-L313 PolarHBondContact O-N 2.91Å; I309-L313 VanDerWaalsContact O-N 3.12Å; T311-L313 VanDerWaalsContact C-N 3.34Å; T311-L313 PolarHBondContact O-N 2.94Å; L313-W315 VanDerWaalsContact C-N 3.29Å; L313-W315 PolarHBondContact O-N 3.36Å; L313-L316 PolarHBondContact O-N 3.13Å; L313-C317 PolarHBondContact O-N 2.63Å; L313-C317 PolarHBondContact O-SG 3.22Å; L313-C317 VanDerWaalsContact O-SG 3.37Å
314	L	92.1	Very high	92.9	Very high	4 Å²	4	33.7 Å²	33.7	2%	0.021	17%	0.171	C	C	.	.	H	α-helix	trans	-63.6	-37.2	174.7	-173.6	66.9	0	0	0	111.4	M45 A95 F118 P184 Q185 F287 S310 T311 C317 Y318	M45-L314 HydrophobicContact CE-CD2 4.37Å; A95-L314 HydrophobicContact CB-CD2 4.06Å; F118-L314 HydrophobicContact CE2-CD1 3.94Å; F118-L314 HydrophobicContact CZ-CD1 4.31Å; P184-L314 HydrophobicContact CB-CD2 4.02Å; Q185-L314 HydrophobicContact CB-CD1 4.01Å; Q185-L314 HydrophobicContact CB-CD2 3.62Å; Q185-L314 HydrophobicContact CB-CG 4.48Å; Q185-L314 HydrophobicContact CG-CD1 4.32Å; F287-L314 HydrophobicContact CE2-CD1 4.5Å; S310-L314 WeakPolarHBondContact O-CB 3.36Å; S310-L314 PolarHBondContact O-N 2.9Å; T311-L314 PolarHBondContact O-N 3.2Å; L314-C317 WeakPolarHBondContact O-CB 3.04Å; L314-C317 PolarHBondContact O-N 3.05Å; L314-Y318 HydrophobicContact CD1-CE1 3.98Å; L314-Y318 HydrophobicContact CD1-CE2 3.95Å; L314-Y318 HydrophobicContact CD2-CD2 4.48Å; L314-Y318 HydrophobicContact CD2-CE2 3.66Å; L314-Y318 HydrophobicContact CG-CD2 3.99Å; L314-Y318 HydrophobicContact CG-CE1 4.42Å; L314-Y318 HydrophobicContact CG-CE2 3.52Å; L314-Y318 PolarHBondContact O-N 2.95Å
315	W	92.9	Very high	92.9	Very high	12 Å²	12	27.5 Å²	27.5	5%	0.045	14%	0.138	C	C	.	.	H	α-helix	trans	-62.9	-42	174.1	-68.4	-6.5	0	0	0	113.5	F40 F41 V44 I48 T311 W312 L313 C317 Y318 L319	F40-W315 HydrophobicContact CD1-CH2 4.11Å; F40-W315 AromaticContact CE1-CH2 3.79Å; F40-W315 HydrophobicContact CE1-CH2 3.79Å; F40-W315 AromaticContact CE1-CZ3 3.84Å; F40-W315 HydrophobicContact CE1-CZ3 3.84Å; F40-W315 HydrophobicContact CZ-CH2 4.46Å; F40-W315 HydrophobicContact CZ-CZ3 4.34Å; F41-W315 VanDerWaalsContact CA-CH2 3.47Å; F41-W315 HydrophobicContact CB-CH2 3.96Å; F41-W315 HydrophobicContact CB-CZ2 3.44Å; F41-W315 VanDerWaalsContact CB-CZ2 3.44Å; F41-W315 AromaticContact CD1-CH2 3Å; F41-W315 HydrophobicContact CD1-CH2 3Å; F41-W315 AromaticContact CD1-CZ2 3.28Å; F41-W315 HydrophobicContact CD1-CZ2 3.28Å; F41-W315 AromaticContact CD1-CZ3 3.84Å; F41-W315 HydrophobicContact CD1-CZ3 3.84Å; F41-W315 HydrophobicContact CD2-CZ2 4.41Å; F41-W315 AromaticContact CE1-CH2 3.59Å; F41-W315 HydrophobicContact CE1-CH2 3.59Å; F41-W315 HydrophobicContact CE1-CZ2 4.04Å; F41-W315 AromaticContact CE1-CZ3 3.96Å; F41-W315 HydrophobicContact CE1-CZ3 3.96Å; F41-W315 AromaticContact CG-CH2 3.72Å; F41-W315 HydrophobicContact CG-CH2 3.72Å; F41-W315 AromaticContact CG-CZ2 3.46Å; F41-W315 HydrophobicContact CG-CZ2 3.46Å; F41-W315 VanDerWaalsContact CG-CZ2 3.46Å; F41-W315 WeakPolarHBondContact O-CZ2 3.35Å; V44-W315 HydrophobicContact CB-CH2 3.57Å; V44-W315 HydrophobicContact CB-CZ2 3.96Å; V44-W315 HydrophobicContact CB-CZ3 3.99Å; V44-W315 HydrophobicContact CG1-CD2 4.15Å; V44-W315 HydrophobicContact CG1-CE3 3.92Å; V44-W315 HydrophobicContact CG1-CH2 3.83Å; V44-W315 HydrophobicContact CG1-CZ2 4.22Å; V44-W315 HydrophobicContact CG1-CZ3 3.75Å; V44-W315 HydrophobicContact CG2-CH2 3.93Å; V44-W315 HydrophobicContact CG2-CZ3 4.22Å; I48-W315 HydrophobicContact CD1-CB 4.36Å; T311-W315 HydrophobicContact CG2-CZ2 4.11Å; T311-W315 VanDerWaalsContact O-CD1 3.25Å; T311-W315 VanDerWaalsContact O-CG 3.28Å; T311-W315 PolarHBondContact O-N 3.4Å; W312-W315 HydrophobicContact CD2-CE3 4.38Å; W312-W315 HydrophobicContact CD2-CZ3 4.44Å; W312-W315 AromaticContact CE3-CE3 3.51Å; W312-W315 HydrophobicContact CE3-CE3 3.51Å; W312-W315 AromaticContact CE3-CZ3 3.68Å; W312-W315 HydrophobicContact CE3-CZ3 3.68Å; W312-W315 AromaticContact CH2-CZ3 3.95Å; W312-W315 HydrophobicContact CH2-CZ3 3.95Å; W312-W315 AromaticContact CZ3-CE3 3.65Å; W312-W315 HydrophobicContact CZ3-CE3 3.65Å; W312-W315 AromaticContact CZ3-CZ3 3.4Å; W312-W315 HydrophobicContact CZ3-CZ3 3.4Å; W312-W315 WeakPolarHBondContact O-CB 3.32Å; W312-W315 PolarHBondContact O-N 3.46Å; L313-W315 VanDerWaalsContact C-N 3.29Å; L313-W315 PolarHBondContact O-N 3.36Å; W315-C317 PolarHBondContact O-N 3.41Å; W315-Y318 PolarHBondContact O-N 2.96Å; W315-L319 WeakPolarHBondContact O-CB 3.48Å; W315-L319 PolarHBondContact O-N 3.47Å
316	L	92.7	Very high	92.9	Very high	63 Å²	63	28.9 Å²	28.9	33%	0.33	14%	0.14	S	C	.	.	H	α-helix	trans	-58.1	-40.3	176.3	-70	175	0	0	0	110.4	C283 P286 W312 L313 L319 K320	C283-L316 WeakPolarHBondContact CB-O 3.38Å; C283-L316 PolarHBondContact SG-O 2.68Å; P286-L316 HydrophobicContact CB-CD1 4.44Å; P286-L316 HydrophobicContact CG-CD1 4.35Å; W312-L316 PolarHBondContact O-N 3.33Å; L313-L316 PolarHBondContact O-N 3.13Å; L316-L319 PolarHBondContact O-N 3.44Å; L316-K320 PolarHBondContact O-N 3.3Å
317	C	92.2	Very high	92.7	Very high	1 Å²	1	29.4 Å²	29.4	1%	0.007	14%	0.143	C	C	.	.	H	α-helix	trans	-64	-45.7	174.9	-62.2	0	0	0	0	112.7	W284 F287 L313 L314 W315 K320	W284-C317 HydrophobicContact CH2-CB 4.21Å; W284-C317 HydrophobicContact CZ2-CB 4.09Å; F287-C317 WeakPolarHBondContact CB-SG 3.4Å; F287-C317 VanDerWaalsContact CD2-SG 3.58Å; F287-C317 WeakPolarHBondContact CG-SG 3.11Å; L313-C317 PolarHBondContact O-N 2.63Å; L313-C317 PolarHBondContact O-SG 3.22Å; L313-C317 VanDerWaalsContact O-SG 3.37Å; L314-C317 WeakPolarHBondContact O-CB 3.04Å; L314-C317 PolarHBondContact O-N 3.05Å; W315-C317 PolarHBondContact O-N 3.41Å; C317-K320 WeakPolarHBondContact O-CB 3.44Å; C317-K320 PolarHBondContact O-N 3.36Å
318	Y	94.8	Very high	92.3	Very high	0 Å²	0	27.8 Å²	27.8	0%	0	14%	0.136	C	C	.	.	H	α-helix	trans	-71	-32.8	179.2	-67	-21.5	0	0	0	112.8	M45 I48 L87 M92 A95 F118 L314 W315 K320 S321 A322	M45-Y318 HydrophobicContact SD-CE2 4.45Å; I48-Y318 WeakPolarHBondContact CG2-O 3.36Å; L87-Y318 HydrophobicContact CD1-CE1 4.39Å; L87-Y318 HydrophobicContact CD2-CD1 4.42Å; L87-Y318 HydrophobicContact CG-CE1 4.44Å; M92-Y318 HydrophobicContact CB-CE2 4.47Å; M92-Y318 HydrophobicContact CE-CD1 3.82Å; M92-Y318 HydrophobicContact CE-CG 3.89Å; M92-Y318 HydrophobicContact CG-CD1 3.96Å; M92-Y318 HydrophobicContact CG-CD2 3.86Å; M92-Y318 HydrophobicContact CG-CE1 4.02Å; M92-Y318 HydrophobicContact CG-CE2 3.92Å; M92-Y318 HydrophobicContact CG-CG 3.88Å; M92-Y318 HydrophobicContact SD-CG 4.21Å; A95-Y318 HydrophobicContact CB-CE2 3.9Å; F118-Y318 HydrophobicContact CD2-CE1 4.2Å; F118-Y318 AromaticContact CE2-CE1 3.81Å; F118-Y318 HydrophobicContact CE2-CE1 3.81Å; L314-Y318 HydrophobicContact CD1-CE1 3.98Å; L314-Y318 HydrophobicContact CD1-CE2 3.95Å; L314-Y318 HydrophobicContact CD2-CD2 4.48Å; L314-Y318 HydrophobicContact CD2-CE2 3.66Å; L314-Y318 HydrophobicContact CG-CD2 3.99Å; L314-Y318 HydrophobicContact CG-CE1 4.42Å; L314-Y318 HydrophobicContact CG-CE2 3.52Å; L314-Y318 PolarHBondContact O-N 2.95Å; W315-Y318 PolarHBondContact O-N 2.96Å; Y318-K320 VanDerWaalsContact C-N 3.27Å; Y318-K320 PolarHBondContact O-N 3.12Å; Y318-S321 VanDerWaalsContact O-CB 3.31Å; Y318-S321 WeakPolarHBondContact O-CB 3.32Å; Y318-S321 PolarHBondContact O-N 3.35Å; Y318-A322 PolarHBondContact O-N 3.3Å
319	L	94	Very high	91.9	Very high	62 Å²	62	29 Å²	29	33%	0.325	14%	0.138	S	C	.	.	H	α-helix	trans	-61.6	-36.1	177.6	-178.3	63	0	0	0	111.1	I48 W315 L316 S321 A322 L323	I48-L319 HydrophobicContact CD1-CB 4.32Å; I48-L319 HydrophobicContact CD1-CD1 4.47Å; I48-L319 HydrophobicContact CG1-CD1 4.3Å; W315-L319 WeakPolarHBondContact O-CB 3.48Å; W315-L319 PolarHBondContact O-N 3.47Å; L316-L319 PolarHBondContact O-N 3.44Å; L319-S321 PolarHBondContact O-N 3.45Å; L319-A322 PolarHBondContact O-N 3.37Å; L319-L323 HydrophobicContact CD1-CG 4.2Å; L319-L323 HydrophobicContact CD2-CD1 4.32Å; L319-L323 HydrophobicContact CG-CD1 3.87Å; L319-L323 HydrophobicContact CG-CG 4.03Å; L319-L323 VanDerWaalsContact O-CG 3.3Å; L319-L323 WeakPolarHBondContact O-CG 3.43Å; L319-L323 PolarHBondContact O-N 2.87Å
320	K	93.1	Very high	91.4	Very high	6 Å²	6	36.5 Å²	36.5	3%	0.026	16%	0.163	C	C	.	.	H	α-helix	trans	-50.8	-43.2	172.1	166.8	-95.6	176.4	-166	0	111.9	D84 C283 L316 C317 Y318 A322 L323 N324	D84-K320 IonicContact OD1-NZ 2.65Å; D84-K320 PolarHBondContact OD1-NZ 2.88Å; D84-K320 IonicContact OD2-NZ 3.39Å; D84-K320 PolarHBondContact OD2-NZ 3.18Å; C283-K320 HydrophobicContact CB-CB 3.7Å; L316-K320 PolarHBondContact O-N 3.3Å; C317-K320 WeakPolarHBondContact O-CB 3.44Å; C317-K320 PolarHBondContact O-N 3.36Å; Y318-K320 VanDerWaalsContact C-N 3.27Å; Y318-K320 PolarHBondContact O-N 3.12Å; K320-A322 VanDerWaalsContact C-N 3.33Å; K320-A322 PolarHBondContact O-N 2.71Å; K320-L323 PolarHBondContact O-N 3.29Å; K320-N324 PolarHBondContact O-N 2.9Å
321	S	94.1	Very high	90.7	Very high	0 Å²	0	39.1 Å²	39.1	0%	0	17%	0.172	C	C	.	.	H	α-helix	trans	-68	-33.4	-178.7	-50.7	0	0	0	0	112.3	N56 D84 Y318 L319 P325	N56-S321 PolarHBondContact ND2-O 3.21Å; D84-S321 PolarHBondContact OD1-OG 3.26Å; Y318-S321 VanDerWaalsContact O-CB 3.31Å; Y318-S321 WeakPolarHBondContact O-CB 3.32Å; Y318-S321 PolarHBondContact O-N 3.35Å; L319-S321 PolarHBondContact O-N 3.45Å; S321-P325 WeakPolarHBondContact O-CD 3.15Å
322	A	94.2	Very high	89.8	Confident	3 Å²	3	41.4 Å²	41.4	3%	0.025	18%	0.184	C	C	.	.	H	α-helix	trans	-75.8	-34.4	174.2	0	0	0	0	0	112.8	I48 V51 A52 Y318 L319 K320	I48-A322 HydrophobicContact CG2-CB 4.23Å; V51-A322 HydrophobicContact CB-CB 4.13Å; V51-A322 HydrophobicContact CG1-CB 3.86Å; A52-A322 HydrophobicContact CB-CB 4.14Å; Y318-A322 PolarHBondContact O-N 3.3Å; L319-A322 PolarHBondContact O-N 3.37Å; K320-A322 VanDerWaalsContact C-N 3.33Å; K320-A322 PolarHBondContact O-N 2.71Å
323	L	93.4	Very high	88.9	Confident	49 Å²	49	42.8 Å²	42.8	26%	0.257	19%	0.193	S	C	.	.	H	α-helix	trans	-71.4	-32.1	-179	-71.1	174.3	0	0	0	112.8	V279 L319 K320 L326 I327	V279-L323 HydrophobicContact CG1-CB 4.09Å; V279-L323 HydrophobicContact CG1-CD1 3.69Å; V279-L323 HydrophobicContact CG2-CD1 4.41Å; L319-L323 HydrophobicContact CD1-CG 4.2Å; L319-L323 HydrophobicContact CD2-CD1 4.32Å; L319-L323 HydrophobicContact CG-CD1 3.87Å; L319-L323 HydrophobicContact CG-CG 4.03Å; L319-L323 VanDerWaalsContact O-CG 3.3Å; L319-L323 WeakPolarHBondContact O-CG 3.43Å; L319-L323 PolarHBondContact O-N 2.87Å; K320-L323 PolarHBondContact O-N 3.29Å; L323-L326 HydrophobicContact CD2-CD1 4.43Å; L323-L326 WeakPolarHBondContact O-CB 3.36Å; L323-L326 PolarHBondContact O-N 3.13Å; L323-L326 VanDerWaalsContact O-N 3.14Å; L323-I327 HydrophobicContact CB-CD1 4.17Å; L323-I327 WeakPolarHBondContact O-CD1 3.46Å; L323-I327 WeakPolarHBondContact O-CG1 3.46Å; L323-I327 PolarHBondContact O-N 2.96Å
324	N	90.1	Very high	87.8	Confident	1 Å²	1	48.7 Å²	48.7	1%	0.005	22%	0.217	C	C	.	.	H	α-helix	trans	-52.5	-57.8	-177.8	-81.9	-12.6	0	0	0	113.1	D84 K320 L326 I327 Y328	D84-N324 PolarHBondContact OD2-ND2 3.12Å; K320-N324 PolarHBondContact O-N 2.9Å; N324-L326 VanDerWaalsContact C-N 3.32Å; N324-L326 PolarHBondContact O-N 2.97Å; N324-I327 PolarHBondContact O-N 3.18Å; N324-Y328 HydrophobicContact CB-CE2 4.17Å; N324-Y328 WeakPolarHBondContact O-CD2 3.43Å; N324-Y328 WeakPolarHBondContact O-CE2 3.15Å; N324-Y328 VanDerWaalsContact O-CG 3.25Å; N324-Y328 PolarHBondContact O-N 3.43Å
325	P	89.4	Confident	86.8	Confident	8 Å²	8	49.1 Å²	49.1	5%	0.052	22%	0.219	C	C	.	.	H	α-helix	trans	-58.3	-37.9	174.8	-25.9	34	0	0	0	114.6	N56 V59 S321 Y328 Y329	N56-P325 HydrophobicContact CB-CG 4.41Å; N56-P325 WeakPolarHBondContact OD1-CG 3.29Å; V59-P325 HydrophobicContact CG2-CB 4.11Å; V59-P325 HydrophobicContact CG2-CG 4.18Å; S321-P325 WeakPolarHBondContact O-CD 3.15Å; P325-Y328 PolarHBondContact O-N 2.84Å; P325-Y329 WeakPolarHBondContact O-CB 3.35Å; P325-Y329 PolarHBondContact O-N 3.15Å
326	L	89.6	Confident	86.3	Confident	92 Å²	92	52.9 Å²	52.9	48%	0.482	23%	0.233	S	C	.	.	H	α-helix	trans	-65.1	-40.5	179.2	-64.6	176.2	0	0	0	111.5	V51 L323 N324 Y329 W330	V51-L326 HydrophobicContact CG1-CD1 4.27Å; V51-L326 HydrophobicContact CG1-CG 4.49Å; L323-L326 HydrophobicContact CD2-CD1 4.43Å; L323-L326 WeakPolarHBondContact O-CB 3.36Å; L323-L326 PolarHBondContact O-N 3.13Å; L323-L326 VanDerWaalsContact O-N 3.14Å; N324-L326 VanDerWaalsContact C-N 3.32Å; N324-L326 PolarHBondContact O-N 2.97Å; L326-Y329 PolarHBondContact O-N 3.48Å; L326-W330 PolarHBondContact O-N 2.84Å
327	I	88.5	Confident	85.6	Confident	15 Å²	15	53 Å²	53	8%	0.077	23%	0.234	C	C	.	.	H	α-helix	trans	-63.3	-45.1	174.4	-65.1	158	0	0	0	109.6	T272 I275 L276 V279 L323 N324 Y329 W330 R331	T272-I327 HydrophobicContact CG2-CG2 3.99Å; I275-I327 HydrophobicContact CG2-CD1 3.93Å; I275-I327 HydrophobicContact CG2-CG1 4.01Å; I275-I327 HydrophobicContact CG2-CG2 4.08Å; L276-I327 HydrophobicContact CD2-CB 4.19Å; L276-I327 HydrophobicContact CD2-CD1 3.86Å; L276-I327 HydrophobicContact CD2-CG2 3.83Å; L276-I327 HydrophobicContact CG-CG2 4.17Å; V279-I327 HydrophobicContact CB-CD1 4.39Å; V279-I327 HydrophobicContact CG1-CD1 4.47Å; V279-I327 HydrophobicContact CG2-CD1 3.97Å; L323-I327 HydrophobicContact CB-CD1 4.17Å; L323-I327 WeakPolarHBondContact O-CD1 3.46Å; L323-I327 WeakPolarHBondContact O-CG1 3.46Å; L323-I327 PolarHBondContact O-N 2.96Å; N324-I327 PolarHBondContact O-N 3.18Å; I327-Y329 PolarHBondContact O-N 3.22Å; I327-W330 PolarHBondContact O-N 2.89Å; I327-R331 HydrophobicContact CG2-CG 4.14Å; I327-R331 WeakPolarHBondContact O-CB 3.2Å; I327-R331 WeakPolarHBondContact O-CG 3.24Å; I327-R331 PolarHBondContact O-N 2.81Å
328	Y	84.3	Confident	84.7	Confident	1 Å²	1	53.8 Å²	53.8	0%	0.004	24%	0.241	C	C	.	.	H	α-helix	trans	-62.2	-43.8	177.5	-54.9	-31.8	0	0	0	112.1	V59 L77 L80 L276 N324 P325 W330 R331 I332	V59-Y328 HydrophobicContact CG1-CD2 4.42Å; V59-Y328 HydrophobicContact CG1-CE2 4.5Å; V59-Y328 HydrophobicContact CG2-CD2 3.8Å; V59-Y328 HydrophobicContact CG2-CE2 4.3Å; L77-Y328 HydrophobicContact CD2-CE1 3.78Å; L77-Y328 WeakPolarHBondContact CD2-OH 3.28Å; L80-Y328 WeakPolarHBondContact CD2-OH 3.49Å; L276-Y328 HydrophobicContact CD1-CE1 3.79Å; L276-Y328 HydrophobicContact CD2-CE1 3.68Å; L276-Y328 HydrophobicContact CG-CE1 4.35Å; N324-Y328 HydrophobicContact CB-CE2 4.17Å; N324-Y328 WeakPolarHBondContact O-CD2 3.43Å; N324-Y328 WeakPolarHBondContact O-CE2 3.15Å; N324-Y328 VanDerWaalsContact O-CG 3.25Å; N324-Y328 PolarHBondContact O-N 3.43Å; P325-Y328 PolarHBondContact O-N 2.84Å; Y328-W330 PolarHBondContact O-N 3.11Å; Y328-R331 PolarHBondContact O-N 3.43Å; Y328-I332 HydrophobicContact CD1-CD1 4.19Å; Y328-I332 HydrophobicContact CG-CD1 4.5Å; Y328-I332 WeakPolarHBondContact O-CB 3.1Å; Y328-I332 PolarHBondContact O-N 2.99Å
329	Y	84.8	Confident	83.7	Confident	92 Å²	92	54.5 Å²	54.5	36%	0.361	25%	0.246	S	C	.	.	H	α-helix	trans	-58.9	-46.5	176.7	-179.8	-95.6	0	0	0	112.7	P325 L326 I327 R336 C339	P325-Y329 WeakPolarHBondContact O-CB 3.35Å; P325-Y329 PolarHBondContact O-N 3.15Å; L326-Y329 PolarHBondContact O-N 3.48Å; I327-Y329 PolarHBondContact O-N 3.22Å; Y329-R336 HydrophobicContact CD2-CB 4.29Å; Y329-R336 HydrophobicContact CD2-CG 4.03Å; Y329-R336 HydrophobicContact CE1-CG 4.28Å; Y329-R336 HydrophobicContact CE2-CB 4.26Å; Y329-R336 HydrophobicContact CE2-CG 3.55Å; Y329-R336 WeakPolarHBondContact O-CB 3.44Å; Y329-C339 HydrophobicContact CD2-CB 4.01Å; Y329-C339 HydrophobicContact CE2-CB 4Å
330	W	82.6	Confident	83	Confident	215 Å²	215	55 Å²	55	81%	0.814	25%	0.249	S	C	*	.	H	α-helix	trans	-73	-35.2	-179	-165.8	2.1	0	0	0	112.2	L326 I327 Y328	L326-W330 PolarHBondContact O-N 2.84Å; I327-W330 PolarHBondContact O-N 2.89Å; Y328-W330 PolarHBondContact O-N 3.11Å
331	R	79.2	Confident	82.1	Confident	58 Å²	58	59.7 Å²	59.7	22%	0.219	27%	0.274	C	S	.	.	H	α-helix	trans	-98.3	-28.4	-166.2	-60.2	-57.6	-56.8	-77.3	-15.5	114.6	R268 T271 T272 I327 Y328	R268-R331 PolarHBondContact O-NH2 2.74Å; T271-R331 VanDerWaalsContact C-NH1 3.26Å; T271-R331 PolarHBondContact O-NH1 3.14Å; T272-R331 HydrophobicContact CG2-CB 3.62Å; T272-R331 HydrophobicContact CG2-CG 4.03Å; T272-R331 WeakPolarHBondContact OG1-CB 3.49Å; T272-R331 PolarHBondContact OG1-NH2 3.05Å; I327-R331 HydrophobicContact CG2-CG 4.14Å; I327-R331 WeakPolarHBondContact O-CB 3.2Å; I327-R331 WeakPolarHBondContact O-CG 3.24Å; I327-R331 PolarHBondContact O-N 2.81Å; Y328-R331 PolarHBondContact O-N 3.43Å
332	I	76.2	Confident	81	Confident	48 Å²	48	63.2 Å²	63.2	25%	0.246	29%	0.292	C	S	.	.			trans	-106.3	101.7	-176.7	-53.8	175.2	0	0	0	108	L77 Y328 K334 F335 R336	L77-I332 HydrophobicContact CD1-CD1 4.5Å; Y328-I332 HydrophobicContact CD1-CD1 4.19Å; Y328-I332 HydrophobicContact CG-CD1 4.5Å; Y328-I332 WeakPolarHBondContact O-CB 3.1Å; Y328-I332 PolarHBondContact O-N 2.99Å; I332-K334 VanDerWaalsContact C-N 3.3Å; I332-K334 HydrophobicContact CG2-CB 4.41Å; I332-K334 PolarHBondContact O-N 3.41Å; I332-F335 HydrophobicContact CB-CB 3.64Å; I332-F335 HydrophobicContact CG2-CB 3.72Å; I332-F335 WeakPolarHBondContact O-CA 3.35Å; I332-F335 VanDerWaalsContact O-CB 3.23Å; I332-F335 WeakPolarHBondContact O-CB 3.4Å; I332-F335 PolarHBondContact O-N 3.25Å; I332-R336 PolarHBondContact O-N 3.07Å
333	K	73.7	Confident	79.8	Confident	142 Å²	142	66.7 Å²	66.7	62%	0.617	31%	0.309	S	S	*	.	H	α-helix	trans	-54.5	-45.1	-179.1	-174.1	179.2	176.4	-174.9	0	112.5	F335 R336 D337	K333-F335 PolarHBondContact O-N 3.39Å; K333-R336 WeakPolarHBondContact O-CB 3.47Å; K333-R336 PolarHBondContact O-N 3.36Å; K333-D337 PolarHBondContact O-N 3.35Å
334	K	71.2	Confident	78.4	Confident	150 Å²	150	68.5 Å²	68.5	65%	0.652	32%	0.324	S	S	*	.	H	α-helix	trans	-58.7	-32.4	175.5	-64.3	-172.2	179.7	-178.4	0	112.7	M69 I332 A338	M69-K334 HydrophobicContact CE-CB 4.41Å; M69-K334 HydrophobicContact SD-CB 4.44Å; M69-K334 HydrophobicContact SD-CD 4.19Å; I332-K334 VanDerWaalsContact C-N 3.3Å; I332-K334 HydrophobicContact CG2-CB 4.41Å; I332-K334 PolarHBondContact O-N 3.41Å; K334-A338 WeakPolarHBondContact O-CB 3.34Å; K334-A338 PolarHBondContact O-N 2.7Å
335	F	72.9	Confident	76.6	Confident	14 Å²	14	77.3 Å²	77.3	6%	0.061	36%	0.362	C	S	.	.	H	α-helix	trans	-72.3	-50.1	177.6	-172.8	-83	0	0	0	110.2	V58 V59 M62 I332 K333 D337 A338 C339	V58-F335 HydrophobicContact CG1-CZ 4.44Å; V59-F335 HydrophobicContact CB-CE2 4.07Å; V59-F335 HydrophobicContact CB-CZ 4.23Å; V59-F335 HydrophobicContact CG1-CE2 4.2Å; V59-F335 HydrophobicContact CG2-CE2 3.61Å; V59-F335 HydrophobicContact CG2-CZ 3.4Å; V59-F335 VanDerWaalsContact CG2-CZ 3.4Å; M62-F335 VanDerWaalsContact CE-CA 3.49Å; M62-F335 HydrophobicContact CE-CB 4.09Å; M62-F335 HydrophobicContact CE-CD1 4.32Å; M62-F335 HydrophobicContact CE-CD2 3.46Å; M62-F335 VanDerWaalsContact CE-CD2 3.46Å; M62-F335 HydrophobicContact CE-CE2 3.86Å; M62-F335 HydrophobicContact CE-CG 3.7Å; M62-F335 HydrophobicContact CE-CZ 4.45Å; M62-F335 VanDerWaalsContact CE-O 3.3Å; M62-F335 WeakPolarHBondContact CE-O 3.38Å; M62-F335 HydrophobicContact SD-CD1 4.36Å; M62-F335 HydrophobicContact SD-CD2 3.84Å; M62-F335 HydrophobicContact SD-CE1 4.19Å; M62-F335 HydrophobicContact SD-CE2 3.58Å; M62-F335 VanDerWaalsContact SD-CE2 3.58Å; M62-F335 HydrophobicContact SD-CG 4.21Å; M62-F335 HydrophobicContact SD-CZ 3.76Å; I332-F335 HydrophobicContact CB-CB 3.64Å; I332-F335 HydrophobicContact CG2-CB 3.72Å; I332-F335 WeakPolarHBondContact O-CA 3.35Å; I332-F335 VanDerWaalsContact O-CB 3.23Å; I332-F335 WeakPolarHBondContact O-CB 3.4Å; I332-F335 PolarHBondContact O-N 3.25Å; K333-F335 PolarHBondContact O-N 3.39Å; F335-D337 VanDerWaalsContact C-N 3.32Å; F335-D337 PolarHBondContact O-N 3.37Å; F335-A338 PolarHBondContact O-N 3.13Å; F335-C339 VanDerWaalsContact CD1-SG 3.54Å; F335-C339 WeakPolarHBondContact CE1-SG 3.36Å; F335-C339 PolarHBondContact O-N 2.97Å; F335-C339 PolarHBondContact O-SG 3.39Å; F335-C339 VanDerWaalsContact O-SG 3.34Å
336	R	81.4	Confident	74.8	Confident	90 Å²	90	87.4 Å²	87.4	34%	0.34	40%	0.4	S	S	.	.	H	α-helix	trans	-53.8	-48.4	175.5	-171	178.4	64.7	-170	4.9	112.8	Y329 I332 K333 A338 C339 L340	Y329-R336 HydrophobicContact CD2-CB 4.29Å; Y329-R336 HydrophobicContact CD2-CG 4.03Å; Y329-R336 HydrophobicContact CE1-CG 4.28Å; Y329-R336 HydrophobicContact CE2-CB 4.26Å; Y329-R336 HydrophobicContact CE2-CG 3.55Å; Y329-R336 WeakPolarHBondContact O-CB 3.44Å; I332-R336 PolarHBondContact O-N 3.07Å; K333-R336 WeakPolarHBondContact O-CB 3.47Å; K333-R336 PolarHBondContact O-N 3.36Å; R336-A338 VanDerWaalsContact C-N 3.32Å; R336-A338 PolarHBondContact O-N 2.76Å; R336-C339 WeakPolarHBondContact O-CB 3.48Å; R336-C339 PolarHBondContact O-N 2.82Å; R336-L340 HydrophobicContact CG-CD1 4.31Å; R336-L340 WeakPolarHBondContact O-CG 3.39Å; R336-L340 PolarHBondContact O-N 3.47Å
337	D	78.9	Confident	73	Confident	65 Å²	65	90.3 Å²	90.3	35%	0.348	41%	0.409	S	S	.	.	H	α-helix	trans	-62.8	-41.5	-177.4	-61.5	-14.4	0	0	0	110.5	K333 F335 L340 D341	K333-D337 PolarHBondContact O-N 3.35Å; F335-D337 VanDerWaalsContact C-N 3.32Å; F335-D337 PolarHBondContact O-N 3.37Å; D337-L340 PolarHBondContact O-N 3.24Å; D337-D341 PolarHBondContact O-N 2.94Å
338	A	71.9	Confident	71.2	Confident	18 Å²	18	95.7 Å²	95.7	15%	0.149	43%	0.433	C	S	.	.	H	α-helix	trans	-72.6	-28.2	175.6	0	0	0	0	0	114.1	M62 K334 F335 R336 D341 L342	M62-A338 HydrophobicContact CE-CB 3.31Å; M62-A338 HydrophobicContact CG-CB 4.47Å; M62-A338 HydrophobicContact SD-CB 4.31Å; K334-A338 WeakPolarHBondContact O-CB 3.34Å; K334-A338 PolarHBondContact O-N 2.7Å; F335-A338 PolarHBondContact O-N 3.13Å; R336-A338 VanDerWaalsContact C-N 3.32Å; R336-A338 PolarHBondContact O-N 2.76Å; A338-D341 PolarHBondContact O-N 3.28Å; A338-L342 PolarHBondContact O-N 3.27Å; A338-L342 VanDerWaalsContact O-N 3.14Å
339	C	74.8	Confident	69.4	Low	16 Å²	16	104.8 Å²	104.8	11%	0.108	47%	0.472	C	S	.	.	H	α-helix	trans	-64.3	-44.2	168	-67.5	0	0	0	0	111.5	V58 Y329 F335 R336 D341 L342 M343	V58-C339 VanDerWaalsContact CG1-SG 3.56Å; Y329-C339 HydrophobicContact CD2-CB 4.01Å; Y329-C339 HydrophobicContact CE2-CB 4Å; F335-C339 VanDerWaalsContact CD1-SG 3.54Å; F335-C339 WeakPolarHBondContact CE1-SG 3.36Å; F335-C339 PolarHBondContact O-N 2.97Å; F335-C339 PolarHBondContact O-SG 3.39Å; F335-C339 VanDerWaalsContact O-SG 3.34Å; R336-C339 WeakPolarHBondContact O-CB 3.48Å; R336-C339 PolarHBondContact O-N 2.82Å; C339-D341 VanDerWaalsContact C-N 3.26Å; C339-D341 PolarHBondContact O-N 2.95Å; C339-L342 PolarHBondContact O-N 2.93Å; C339-L342 VanDerWaalsContact O-N 3.1Å; C339-M343 WeakPolarHBondContact O-CG 3.37Å; C339-M343 PolarHBondContact O-N 3.18Å
340	L	78.6	Confident	67.6	Low	72 Å²	72	108 Å²	108	38%	0.377	50%	0.495	S	S	.	.	H	α-helix	trans	-64.8	-30.8	177.9	-68.6	171.8	0	0	0	112.3	R336 D337 M343	R336-L340 HydrophobicContact CG-CD1 4.31Å; R336-L340 WeakPolarHBondContact O-CG 3.39Å; R336-L340 PolarHBondContact O-N 3.47Å; D337-L340 PolarHBondContact O-N 3.24Å; L340-M343 HydrophobicContact CD2-SD 4.06Å
341	D	75.2	Confident	65.7	Low	104 Å²	104	103.1 Å²	103.1	56%	0.556	49%	0.491	S	S	*	.	H	α-helix	trans	-71.4	-30.6	172.6	-73.7	-17.9	0	0	0	112.9	D337 A338 C339	D337-D341 PolarHBondContact O-N 2.94Å; A338-D341 PolarHBondContact O-N 3.28Å; C339-D341 VanDerWaalsContact C-N 3.26Å; C339-D341 PolarHBondContact O-N 2.95Å
342	L	69.6	Low	63.9	Low	74 Å²	74	108.8 Å²	108.8	39%	0.387	52%	0.52	S	S	.	.	H	α-helix	trans	-78.9	-22.8	177	-132.2	82.3	0	0	0	112.6	V58 L61 A338 C339	V58-L342 HydrophobicContact CG2-CD2 4.48Å; L61-L342 HydrophobicContact CD1-CD2 4.19Å; A338-L342 PolarHBondContact O-N 3.27Å; A338-L342 VanDerWaalsContact O-N 3.14Å; C339-L342 PolarHBondContact O-N 2.93Å; C339-L342 VanDerWaalsContact O-N 3.1Å
343	M	70.6	Confident	62.7	Low	77 Å²	77	114.4 Å²	114.4	38%	0.379	55%	0.55	S	S	.	.	S	Bend	trans	-65.2	130.8	179.1	-77	-179.2	68.5	0	0	110.8	C339 L340 K345 F347	C339-M343 WeakPolarHBondContact O-CG 3.37Å; C339-M343 PolarHBondContact O-N 3.18Å; L340-M343 HydrophobicContact CD2-SD 4.06Å; M343-K345 PolarHBondContact O-N 2.97Å; M343-F347 HydrophobicContact CE-CB 3.62Å; M343-F347 HydrophobicContact CE-CG 4.27Å
344	P	62.7	Low	60.9	Low	87 Å²	87	113.4 Å²	113.4	57%	0.565	56%	0.558	S	S	*	*			trans	-52.3	139.8	177	-23.6	31.1	0	0	0	110.9	Y346 F347	P344-Y346 PolarHBondContact O-N 2.78Å; P344-F347 PolarHBondContact O-N 3.28Å
345	K	52.2	Low	59.5	Low	185 Å²	185	109 Å²	109	80%	0.804	56%	0.555	S	S	*	*	G	3₁₀ helix	trans	-52.9	-18.1	-178	-70	-180	-179.9	177	0	114.1	M343	M343-K345 PolarHBondContact O-N 2.97Å
346	Y	51.2	Low	58	Low	220 Å²	220	116.2 Å²	116.2	86%	0.863	59%	0.594	S	S	*	*	G	3₁₀ helix	trans	-68.1	-26.6	174.5	-106	-90.9	0	0	0	115.1	P344	P344-Y346 PolarHBondContact O-N 2.78Å
347	F	53.7	Low	56.1	Low	153 Å²	153	118 Å²	118	67%	0.671	62%	0.616	S	S	*	*	G	3₁₀ helix	trans	-94.1	6.6	-179.8	-86.8	-83.9	0	0	0	114	M343 P344 F349	M343-F347 HydrophobicContact CE-CB 3.62Å; M343-F347 HydrophobicContact CE-CG 4.27Å; P344-F347 PolarHBondContact O-N 3.28Å; F347-F349 PolarHBondContact O-N 3.38Å
348	K	49.6	Very low	54.2	Low	129 Å²	129	124.6 Å²	124.6	56%	0.561	64%	0.641	S	S	*	*			trans	-76.9	50.9	174.1	-74.6	-171.9	175.8	-176	0	112.3
349	F	46.7	Very low	52.6	Low	192 Å²	192	134.2 Å²	134.2	84%	0.842	67%	0.674	S	S	*	*			trans	-93.1	2.6	177.8	-123.1	-82.6	0	0	0	113.9	F347	F347-F349 PolarHBondContact O-N 3.38Å
350	L	46.8	Very low	50.8	Low	158 Å²	158	145.2 Å²	145.2	83%	0.827	71%	0.713	S	S	*	*	S	Bend	trans	-92.5	114.8	170.5	-88.9	145.2	0	0	0	108.9	Q352	L350-Q352 PolarHBondContact O-N 2.77Å
351	P	42.5	Very low	48.9	Very low	114 Å²	114	148.3 Å²	148.3	74%	0.74	73%	0.728	S	S	*	*			trans	-61.6	129.4	-179.8	24.4	-30.4	0	0	0	109	L353	P351-L353 PolarHBondContact O-N 3.16Å
352	Q	42.7	Very low	47.1	Very low	176 Å²	176	151.2 Å²	151.2	82%	0.822	74%	0.739	S	S	*	*			trans	-63.1	110.2	170.2	-67.2	-161.3	-4.1	0	0	108.3	L350	L350-Q352 PolarHBondContact O-N 2.77Å
353	L	49.5	Very low	45.5	Very low	166 Å²	166	153.6 Å²	153.6	87%	0.869	76%	0.758	S	S	*	*			trans	-60.5	124.9	160.5	-87.2	137.2	0	0	0	107.5	P351 G355	P351-L353 PolarHBondContact O-N 3.16Å; L353-G355 VanDerWaalsContact C-N 3.29Å; L353-G355 PolarHBondContact O-N 3.41Å
354	P	37.3	Very low	43.9	Very low	121 Å²	121	154.2 Å²	154.2	79%	0.786	77%	0.77	S	S	*	*			trans	-67.6	92	179.4	25.8	-30.3	0	0	0	108.9	N356	P354-N356 PolarHBondContact O-N 2.73Å; P354-N356 VanDerWaalsContact O-N 3.16Å
355	G	40.9	Very low	43	Very low	59 Å²	59	154.5 Å²	154.5	61%	0.608	78%	0.78	S	S	*	*			trans	-70.3	106.2	167	0	0	0	0	0	108	L353 T357	L353-G355 VanDerWaalsContact C-N 3.29Å; L353-G355 PolarHBondContact O-N 3.41Å; G355-T357 VanDerWaalsContact C-N 3.33Å; G355-T357 PolarHBondContact O-N 3.32Å; G355-T357 PolarHBondContact O-OG1 2.93Å; G355-T357 VanDerWaalsContact O-OG1 3.09Å
356	N	42	Very low	42.5	Very low	164 Å²	164	151.4 Å²	151.4	88%	0.877	78%	0.776	S	S	*	*			trans	-40.4	94.4	170.7	-84.1	-42.9	0	0	0	111.3	P354 K358	P354-N356 PolarHBondContact O-N 2.73Å; P354-N356 VanDerWaalsContact O-N 3.16Å; N356-K358 VanDerWaalsContact C-N 3.28Å; N356-K358 PolarHBondContact O-N 2.86Å
357	T	42	Very low	41.6	Very low	128 Å²	128	152.3 Å²	152.3	79%	0.785	78%	0.78	S	S	*	*			trans	-82.8	84.5	173.3	-50.6	0	0	0	0	105.4	G355 R359	G355-T357 VanDerWaalsContact C-N 3.33Å; G355-T357 PolarHBondContact O-N 3.32Å; G355-T357 PolarHBondContact O-OG1 2.93Å; G355-T357 VanDerWaalsContact O-OG1 3.09Å; T357-R359 PolarHBondContact O-N 2.8Å
358	K	38.4	Very low	40.8	Very low	203 Å²	203	152.9 Å²	152.9	88%	0.883	79%	0.788	S	S	*	*			trans	-62.6	92.7	163.9	-87	-171.8	176.6	-178	0	107.2	N356 R360	N356-K358 VanDerWaalsContact C-N 3.28Å; N356-K358 PolarHBondContact O-N 2.86Å; K358-R360 PolarHBondContact O-N 2.77Å
359	R	38.1	Very low	40	Very low	221 Å²	221	152.7 Å²	152.7	83%	0.834	80%	0.801	S	S	*	*			trans	-56.4	103.3	161.6	-120.8	180	-179.9	179.9	0.1	106.2	T357 I361	T357-R359 PolarHBondContact O-N 2.8Å; R359-I361 PolarHBondContact O-N 3.16Å
360	R	37.8	Very low	39.4	Very low	247 Å²	247	146.7 Å²	146.7	93%	0.932	79%	0.794	S	S	*	*			trans	-75.7	84.5	169.5	-157	179.9	-148.5	-176.7	6.8	106.4	K358 Q362	K358-R360 PolarHBondContact O-N 2.77Å; R360-Q362 PolarHBondContact O-N 2.97Å
361	I	38.4	Very low	38.7	Very low	136 Å²	136	147.4 Å²	147.4	70%	0.697	79%	0.793	S	S	*	*			trans	-65.6	128.1	165.5	-61.2	172.4	0	0	0	105.9	R359 P363	R359-I361 PolarHBondContact O-N 3.16Å; I361-P363 WeakPolarHBondContact O-CD 3.46Å
362	Q	37.5	Very low	38.4	Very low	166 Å²	166	151 Å²	151	78%	0.776	80%	0.8	S	S	*	*			trans	-87.3	110.9	178.5	-151.5	176.2	3.1	0	0	106.9	R360 S364	R360-Q362 PolarHBondContact O-N 2.97Å; Q362-S364 PolarHBondContact O-N 2.86Å
363	P	35.3	Very low	38	Very low	124 Å²	124	153.1 Å²	153.1	81%	0.805	80%	0.8	S	S	*	*			trans	-92.9	88.5	165.1	24.8	-7.6	0	0	0	106.8	I361	I361-P363 WeakPolarHBondContact O-CD 3.46Å
364	S	37.6	Very low	37.3	Very low	89 Å²	89	150.3 Å²	150.3	62%	0.622	79%	0.794	S	S	*	*			trans	-78.9	135	158.4	-43.7	0	0	0	0	107.1	Q362	Q362-S364 PolarHBondContact O-N 2.86Å
365	A	42.7	Very low	37.4	Very low	93 Å²	93	150.2 Å²	150.2	77%	0.769	79%	0.791	S	S	*	*			trans	81.1	101.2	177.3	0	0	0	0	0	115.9
366	V	41.5	Very low	37.1	Very low	120 Å²	120	157.5 Å²	157.5	73%	0.727	82%	0.823	S	S	*	*				172.8	105.6	115.7	169.5	0	0	0	0	106.7
367	Y	32.7	Very low	36.9	Very low	240 Å²	240	157.2 Å²	157.2	94%	0.941	82%	0.821	S	S	*	*			trans	-147.4	92.8	151	-78.9	-72.4	0	0	0	107.3
368	I	36.2	Very low	36.6	Very low	164 Å²	164	158.7 Å²	158.7	84%	0.841	82%	0.822	S	S	*	*			trans	-84	113.2	157.5	-65.7	171.9	0	0	0	104.7
369	C	33	Very low	36.5	Very low	125 Å²	125	156.2 Å²	156.2	85%	0.845	82%	0.819	S	S	*	*			trans	-88.2	113.6	171.5	-164.2	0	0	0	0	107.3
370	G	33.8	Very low	36.4	Very low	66 Å²	66	152.4 Å²	152.4	68%	0.68	82%	0.818	S	S	*	*			trans	-78.4	119.5	168.3	0	0	0	0	0	109.6	H372	G370-H372 PolarHBondContact O-N 3.16Å
371	E	33.9	Very low	36.3	Very low	174 Å²	174	146.5 Å²	146.5	81%	0.813	81%	0.811	S	S	*	*			trans	-64	115.9	166.4	-83.3	179.1	125.4	0	0	109.9
372	H	34.4	Very low	36.2	Very low	190 Å²	190	147.2 Å²	147.2	88%	0.88	82%	0.819	S	S	*	*			trans	-89.3	105.7	152	-111.2	-70.7	0	0	0	107.5	G370	G370-H372 PolarHBondContact O-N 3.16Å
373	R	34.3	Very low	36.1	Very low	219 Å²	219	145.9 Å²	145.9	83%	0.826	82%	0.822	S	S	*	*			trans	-96.5	103.7	166.7	-132.9	178.8	-173.7	177.7	2	107.5
374	S	35	Very low	36.2	Very low	108 Å²	108	147.5 Å²	147.5	76%	0.755	82%	0.823	S	S	*	*			trans	-105.9	112	161.8	45.5	0	0	0	0	107.5
375	V	39.4	Very low	36	Very low	119 Å²	119	152.4 Å²	152.4	72%	0.721	84%	0.84	S	S	*	*			trans	-134	113.2	163.5	-177.8	0	0	0	0	106.6
376	V	35.6	Very low	35.4	Very low	211 Å²	211	157.8 Å²	157.8	100%	1.279	85%	0.846	S	S	*	*			trans	45.1	0	145.9	-170.3	0	0	0	0	118.4

Retrieved 376 of 376 residues in 369.6 ms (Link to these results)

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