A0A089H974_HUMAN Loading...

C-C chemokine receptor type 5

Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor.

AlphaFold DB , UniProt , Accession A0A089H974, Species HUMAN (Homo sapiens, Human), Gene CCR5, Length 352 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	40.4	Very low	40.4	Very low	217 Å²	217	150.1 Å²	150.1	100%	1.069	77%	0.774	S	S	*	*				0	88.7	0	-83.9	-173	-178.3	0	0	105.2	Y3	M1-Y3 PolarHBondContact O-N 3.06Å
2	D	35.1	Very low	40.5	Very low	157 Å²	157	149.8 Å²	149.8	84%	0.84	77%	0.773	S	S	*	*			trans	-87	111.2	-170.1	-60.2	-29	0	0	0	108.8	Q4	D2-Q4 PolarHBondContact O-N 3.08Å
3	Y	41.6	Very low	40.5	Very low	214 Å²	214	148.6 Å²	148.6	84%	0.839	77%	0.768	S	S	*	*			trans	-81.2	99.7	168.5	-79.2	-88.2	0	0	0	108.5	M1 V5	M1-Y3 PolarHBondContact O-N 3.06Å; Y3-V5 PolarHBondContact O-N 3.26Å
4	Q	37.6	Very low	40.3	Very low	175 Å²	175	152 Å²	152	82%	0.818	77%	0.768	S	S	*	*			trans	-84.1	100.8	163.6	-85	173.4	-39.8	0	0	109.2	D2	D2-Q4 PolarHBondContact O-N 3.08Å
5	V	49.7	Very low	40.8	Very low	145 Å²	145	157.3 Å²	157.3	88%	0.879	78%	0.777	S	S	*	*			trans	-94.2	97.7	156.5	179.5	0	0	0	0	106.5	Y3	Y3-V5 PolarHBondContact O-N 3.26Å
6	S	44	Very low	41	Very low	100 Å²	100	153.9 Å²	153.9	70%	0.699	77%	0.768	S	S	*	*			trans	-132.9	97.6	174.4	58.2	0	0	0	0	110.3
7	S	41.4	Very low	41.5	Very low	80 Å²	80	151.6 Å²	151.6	56%	0.559	77%	0.771	S	S	*	*			trans	-163.3	116.8	147.3	-169.9	0	0	0	0	109.3	I9	S7-I9 PolarHBondContact O-N 3.14Å; S7-I9 WeakPolarHBondContact OG-CG1 3.3Å; S7-I9 PolarHBondContact OG-N 3.48Å
8	P	42.2	Very low	42.2	Very low	112 Å²	112	153.4 Å²	153.4	73%	0.727	78%	0.776	S	S	*	*			trans	-90.9	64.4	160.6	36.4	-26.3	0	0	0	107.7	Y10	P8-Y10 HydrophobicContact CB-CE2 4.25Å; P8-Y10 PolarHBondContact O-N 3.41Å
9	I	37.4	Very low	43.2	Very low	124 Å²	124	151.3 Å²	151.3	64%	0.636	77%	0.774	S	S	*	*			trans	-78.9	100.8	154.7	-71.1	167.4	0	0	0	103.8	S7 D11	S7-I9 PolarHBondContact O-N 3.14Å; S7-I9 WeakPolarHBondContact OG-CG1 3.3Å; S7-I9 PolarHBondContact OG-N 3.48Å; I9-D11 PolarHBondContact O-N 3.15Å
10	Y	39.4	Very low	44.4	Very low	209 Å²	209	145.9 Å²	145.9	82%	0.82	75%	0.749	S	S	*	*			trans	-65.3	89	166.2	-72.8	-86.7	0	0	0	107	P8 I12	P8-Y10 HydrophobicContact CB-CE2 4.25Å; P8-Y10 PolarHBondContact O-N 3.41Å; Y10-I12 VanDerWaalsContact C-N 3.33Å; Y10-I12 PolarHBondContact O-N 2.89Å
11	D	35.2	Very low	45.4	Very low	118 Å²	118	146 Å²	146	63%	0.631	75%	0.747	S	S	*	*			trans	-61.3	103.4	160.3	-86.5	-26.9	0	0	0	106.2	I9 N13	I9-D11 PolarHBondContact O-N 3.15Å; D11-N13 PolarHBondContact O-N 3.3Å
12	I	42.1	Very low	46.7	Very low	147 Å²	147	140.1 Å²	140.1	75%	0.754	72%	0.715	S	S	*	*			trans	-68	77.5	164.3	-61.9	170.2	0	0	0	105.4	Y10 Y14	Y10-I12 VanDerWaalsContact C-N 3.33Å; Y10-I12 PolarHBondContact O-N 2.89Å; I12-Y14 HydrophobicContact CG2-CD2 3.79Å; I12-Y14 HydrophobicContact CG2-CE2 4.34Å; I12-Y14 PolarHBondContact O-N 3.12Å
13	N	40	Very low	48	Very low	134 Å²	134	137.1 Å²	137.1	72%	0.717	70%	0.698	S	S	*	*			trans	-71.5	80.2	171.7	-87.3	-43.9	0	0	0	108.3	D11 Y15	D11-N13 PolarHBondContact O-N 3.3Å; N13-Y15 PolarHBondContact O-N 3.42Å
14	Y	38.5	Very low	49.3	Very low	196 Å²	196	132.7 Å²	132.7	77%	0.769	69%	0.689	S	S	*	*			trans	-75.7	105.7	153.6	-100	-95	0	0	0	107.3	I12 T16	I12-Y14 HydrophobicContact CG2-CD2 3.79Å; I12-Y14 HydrophobicContact CG2-CE2 4.34Å; I12-Y14 PolarHBondContact O-N 3.12Å; Y14-T16 PolarHBondContact O-N 3.33Å
15	Y	46.8	Very low	51	Low	231 Å²	231	125.8 Å²	125.8	91%	0.906	66%	0.659	S	S	*	*	S	Bend	trans	-57.6	83.4	161.3	-115.5	-96	0	0	0	108.9	N13	N13-Y15 PolarHBondContact O-N 3.42Å
16	T	45	Very low	52.1	Low	103 Å²	103	124.5 Å²	124.5	63%	0.632	64%	0.641	S	S	*	*	S	Bend	trans	176.8	119.8	166.6	35.9	0	0	0	0	109.9	Y14	Y14-T16 PolarHBondContact O-N 3.33Å
17	S	49.7	Very low	53.9	Low	116 Å²	116	125.1 Å²	125.1	81%	0.811	63%	0.633	S	S	*	*			trans	39.8	86.6	152.8	-43.2	0	0	0	0	116.4
18	E	52.8	Low	55.8	Low	183 Å²	183	126.8 Å²	126.8	86%	0.855	63%	0.634	S	S	*	*			trans	-51.8	128.9	166.9	-73	-174.5	167.7	0	0	110.1	C20	E18-C20 PolarHBondContact O-N 2.88Å
19	P	62.5	Low	57.8	Low	114 Å²	114	122.2 Å²	122.2	74%	0.74	61%	0.606	S	S	*	*			trans	-60.5	123.8	175.9	21.3	-29.3	0	0	0	109.4	Q21	P19-Q21 PolarHBondContact O-N 3.32Å
20	C	67.5	Low	60.1	Low	42 Å²	42	117.7 Å²	117.7	28%	0.284	59%	0.587	S	S	.	*			trans	-50.6	107.9	-178.5	-172.3	0	0	0	0	110.3	E18 K22 C269	E18-C20 PolarHBondContact O-N 2.88Å; C20-K22 PolarHBondContact O-N 3.17Å; C20-C269 HydrophobicContact CB-CB 4.07Å; C20-C269 WeakPolarHBondContact CB-SG 3.48Å; C20-C269 WeakPolarHBondContact SG-CB 3.45Å; C20-C269 PolarHBondContact SG-O 3.47Å; C20-C269 CovalentContact SG-SG 2.06Å; C20-C269 PolarHBondContact SG-SG 3.01Å
21	Q	64.3	Low	62.5	Low	150 Å²	150	117.9 Å²	117.9	70%	0.701	59%	0.587	S	S	*	*			trans	-74.9	124	-172.5	-70.3	-158.8	-13.7	0	0	112.2	P19	P19-Q21 PolarHBondContact O-N 3.32Å
22	K	67	Low	65.1	Low	93 Å²	93	117.5 Å²	117.5	40%	0.404	58%	0.584	S	S	.	*			trans	-109.6	24.7	-175.2	-54.9	-178.2	-168	175.5	0	114.4	C20 N24 V25 D276	C20-K22 PolarHBondContact O-N 3.17Å; K22-N24 PolarHBondContact O-N 3.37Å; K22-V25 PolarHBondContact O-N 3.02Å; K22-D276 WeakPolarHBondContact CE-OD2 3.31Å; K22-D276 IonicContact NZ-OD1 3.73Å; K22-D276 IonicContact NZ-OD2 2.59Å; K22-D276 PolarHBondContact NZ-OD2 2.78Å
23	I	63.6	Low	67.5	Low	93 Å²	93	110.9 Å²	110.9	48%	0.477	55%	0.55	S	S	.	*	H	α-helix	trans	-57.1	-42.1	-164.7	-61.4	172.3	0	0	0	113.1	V25	I23-V25 VanDerWaalsContact C-N 3.33Å; I23-V25 PolarHBondContact O-N 3.3Å
24	N	68.9	Low	70.1	Confident	121 Å²	121	105.6 Å²	105.6	65%	0.647	52%	0.523	S	S	*	.	H	α-helix	trans	-67.1	-30.8	-175.6	-68.3	-13.6	0	0	0	113.6	K22 I28	K22-N24 PolarHBondContact O-N 3.37Å; N24-I28 WeakPolarHBondContact O-CD1 3.31Å; N24-I28 WeakPolarHBondContact O-CG1 3.18Å; N24-I28 PolarHBondContact O-N 2.84Å
25	V	72.4	Confident	72.8	Confident	31 Å²	31	99.9 Å²	99.9	19%	0.188	51%	0.51	C	S	.	.	H	α-helix	trans	-75.7	-43.1	-175.1	-175.4	0	0	0	0	111	K22 I23 Q27 I28 A29 Q277	K22-V25 PolarHBondContact O-N 3.02Å; I23-V25 VanDerWaalsContact C-N 3.33Å; I23-V25 PolarHBondContact O-N 3.3Å; V25-Q27 VanDerWaalsContact C-N 3.32Å; V25-Q27 PolarHBondContact O-N 3.27Å; V25-I28 PolarHBondContact O-N 3.13Å; V25-A29 WeakPolarHBondContact O-CB 3.24Å; V25-A29 PolarHBondContact O-N 3.09Å; V25-Q277 HydrophobicContact CB-CG 4.28Å; V25-Q277 HydrophobicContact CG1-CG 3.82Å; V25-Q277 HydrophobicContact CG2-CG 3.41Å; V25-Q277 VanDerWaalsContact CG2-CG 3.41Å
26	K	74.3	Confident	75	Confident	117 Å²	117	91.6 Å²	91.6	51%	0.509	48%	0.481	S	S	.	.	H	α-helix	trans	-62.4	-40.2	-178.8	-168.9	177.9	179.5	-176.5	0	111.5	A29 A30	K26-A29 PolarHBondContact O-N 3.46Å; K26-A30 VanDerWaalsContact O-CB 3.3Å; K26-A30 WeakPolarHBondContact O-CB 3.38Å; K26-A30 PolarHBondContact O-N 3.03Å
27	Q	80.3	Confident	77.4	Confident	114 Å²	114	86.9 Å²	86.9	53%	0.533	45%	0.452	S	S	.	.	H	α-helix	trans	-67.9	-39.8	179.2	-69	-179.4	-5.7	0	0	113	V25 R31	V25-Q27 VanDerWaalsContact C-N 3.32Å; V25-Q27 PolarHBondContact O-N 3.27Å; Q27-R31 PolarHBondContact O-N 3.34Å
28	I	82.1	Confident	79.6	Confident	114 Å²	114	84.2 Å²	84.2	59%	0.585	43%	0.433	S	S	*	.	H	α-helix	trans	-66.7	-46	176.3	-66	169.7	0	0	0	109.9	N24 V25 A30 R31 L32	N24-I28 WeakPolarHBondContact O-CD1 3.31Å; N24-I28 WeakPolarHBondContact O-CG1 3.18Å; N24-I28 PolarHBondContact O-N 2.84Å; V25-I28 PolarHBondContact O-N 3.13Å; I28-A30 VanDerWaalsContact C-N 3.33Å; I28-A30 PolarHBondContact O-N 2.83Å; I28-R31 PolarHBondContact O-N 3.11Å; I28-L32 PolarHBondContact O-N 3.27Å; I28-L32 VanDerWaalsContact O-N 3.07Å
29	A	83.6	Confident	81.6	Confident	16 Å²	16	79.7 Å²	79.7	13%	0.132	41%	0.414	C	S	.	.	H	α-helix	trans	-58.7	-43.4	176.5	0	0	0	0	0	111.8	V25 K26 R31 L32 L33	V25-A29 WeakPolarHBondContact O-CB 3.24Å; V25-A29 PolarHBondContact O-N 3.09Å; K26-A29 PolarHBondContact O-N 3.46Å; A29-R31 PolarHBondContact O-N 3.18Å; A29-L32 PolarHBondContact O-N 3.41Å; A29-L33 HydrophobicContact CB-CD1 3.8Å; A29-L33 HydrophobicContact CB-CG 4.22Å; A29-L33 VanDerWaalsContact O-CB 3.27Å; A29-L33 WeakPolarHBondContact O-CB 3.29Å; A29-L33 VanDerWaalsContact O-CG 3.25Å; A29-L33 WeakPolarHBondContact O-CG 3.44Å; A29-L33 PolarHBondContact O-N 3.37Å
30	A	85.8	Confident	83.2	Confident	29 Å²	29	74.6 Å²	74.6	24%	0.24	38%	0.381	C	S	.	.	H	α-helix	trans	-62.4	-26.1	178.7	0	0	0	0	0	114.2	K26 I28 P34 A90	K26-A30 VanDerWaalsContact O-CB 3.3Å; K26-A30 WeakPolarHBondContact O-CB 3.38Å; K26-A30 PolarHBondContact O-N 3.03Å; I28-A30 VanDerWaalsContact C-N 3.33Å; I28-A30 PolarHBondContact O-N 2.83Å; A30-P34 VanDerWaalsContact O-CD 3.27Å; A30-P34 WeakPolarHBondContact O-CD 3.28Å; A30-P34 VanDerWaalsContact O-CG 3.27Å; A30-P34 WeakPolarHBondContact O-CG 3.46Å; A30-A90 WeakPolarHBondContact CA-O 3.33Å; A30-A90 WeakPolarHBondContact CB-O 3.49Å
31	R	89.5	Confident	84.6	Confident	213 Å²	213	75.4 Å²	75.4	80%	0.804	38%	0.38	S	S	*	.	H	α-helix	trans	-87.9	-35.8	176.4	-67.7	-179.1	-177.3	-172.9	1.7	112.9	Q27 I28 A29 P35	Q27-R31 PolarHBondContact O-N 3.34Å; I28-R31 PolarHBondContact O-N 3.11Å; A29-R31 PolarHBondContact O-N 3.18Å; R31-P35 WeakPolarHBondContact O-CD 3.36Å; R31-P35 WeakPolarHBondContact O-CG 3.5Å
32	L	90.9	Very high	86.1	Confident	110 Å²	110	72.9 Å²	72.9	58%	0.576	37%	0.37	S	S	*	.	H	α-helix	trans	-91.3	-40.2	-172.3	-173.6	67.5	0	0	0	113.6	I28 A29 P35 L36	I28-L32 PolarHBondContact O-N 3.27Å; I28-L32 VanDerWaalsContact O-N 3.07Å; A29-L32 PolarHBondContact O-N 3.41Å; L32-P35 WeakPolarHBondContact O-CD 3.45Å; L32-P35 WeakPolarHBondContact O-CG 3.34Å; L32-L36 WeakPolarHBondContact O-CB 3.48Å; L32-L36 PolarHBondContact O-N 2.93Å
33	L	91.8	Very high	87.5	Confident	8 Å²	8	74.4 Å²	74.4	4%	0.042	38%	0.377	C	S	.	.	H	α-helix	trans	-68.3	-44.4	-172.8	-61.9	180	0	0	0	113.4	A29 L36 Y37 A90 T284	A29-L33 HydrophobicContact CB-CD1 3.8Å; A29-L33 HydrophobicContact CB-CG 4.22Å; A29-L33 VanDerWaalsContact O-CB 3.27Å; A29-L33 WeakPolarHBondContact O-CB 3.29Å; A29-L33 VanDerWaalsContact O-CG 3.25Å; A29-L33 WeakPolarHBondContact O-CG 3.44Å; A29-L33 PolarHBondContact O-N 3.37Å; L33-L36 PolarHBondContact O-N 2.99Å; L33-Y37 HydrophobicContact CB-CD2 4.39Å; L33-Y37 HydrophobicContact CB-CE2 4.11Å; L33-Y37 HydrophobicContact CD2-CE1 4.25Å; L33-Y37 VanDerWaalsContact O-CB 3.3Å; L33-Y37 WeakPolarHBondContact O-CB 3.41Å; L33-Y37 PolarHBondContact O-N 3.43Å; L33-A90 HydrophobicContact CB-CB 3.86Å; L33-A90 HydrophobicContact CD1-CB 3.92Å; L33-T284 HydrophobicContact CD2-CG2 3.52Å; L33-T284 VanDerWaalsContact CD2-OG1 3.25Å; L33-T284 WeakPolarHBondContact CD2-OG1 3.49Å
34	P	93.9	Very high	89	Confident	23 Å²	23	70 Å²	70	15%	0.149	35%	0.354	C	S	.	.	H	α-helix	trans	-58.9	-49	-177.8	-22.4	33	0	0	0	114.9	A30 L36 S38 A91	A30-P34 VanDerWaalsContact O-CD 3.27Å; A30-P34 WeakPolarHBondContact O-CD 3.28Å; A30-P34 VanDerWaalsContact O-CG 3.27Å; A30-P34 WeakPolarHBondContact O-CG 3.46Å; P34-L36 PolarHBondContact O-N 3.25Å; P34-S38 WeakPolarHBondContact O-CB 3.15Å; P34-S38 PolarHBondContact O-N 3.37Å; P34-S38 PolarHBondContact O-OG 3.28Å; P34-A91 HydrophobicContact CB-CB 4.42Å; P34-A91 HydrophobicContact CG-CB 3.68Å
35	P	95.2	Very high	90.3	Very high	77 Å²	77	67.8 Å²	67.8	50%	0.5	34%	0.339	S	S	.	.	H	α-helix	trans	-66.7	-37.2	177.2	25.6	-33.1	0	0	0	112	R31 L32 S38 L39	R31-P35 WeakPolarHBondContact O-CD 3.36Å; R31-P35 WeakPolarHBondContact O-CG 3.5Å; L32-P35 WeakPolarHBondContact O-CD 3.45Å; L32-P35 WeakPolarHBondContact O-CG 3.34Å; P35-S38 PolarHBondContact O-N 3.08Å; P35-L39 PolarHBondContact O-N 3.03Å
36	L	94.9	Very high	91.4	Very high	56 Å²	56	70.7 Å²	70.7	29%	0.293	36%	0.357	S	S	.	.	H	α-helix	trans	-63.8	-49	177.4	178.7	62.5	0	0	0	111.7	L32 L33 P34 S38 L39 V40 T284 T288	L32-L36 WeakPolarHBondContact O-CB 3.48Å; L32-L36 PolarHBondContact O-N 2.93Å; L33-L36 PolarHBondContact O-N 2.99Å; P34-L36 PolarHBondContact O-N 3.25Å; L36-S38 VanDerWaalsContact C-N 3.31Å; L36-S38 PolarHBondContact O-N 3.27Å; L36-L39 WeakPolarHBondContact O-CB 3.39Å; L36-L39 PolarHBondContact O-N 2.9Å; L36-L39 VanDerWaalsContact O-N 3.17Å; L36-V40 VanDerWaalsContact O-CG2 3.32Å; L36-V40 WeakPolarHBondContact O-CG2 3.49Å; L36-V40 PolarHBondContact O-N 3.18Å; L36-T284 HydrophobicContact CD2-CG2 3.51Å; L36-T288 HydrophobicContact CD2-CG2 4.5Å
37	Y	95.1	Very high	92.3	Very high	4 Å²	4	65.8 Å²	65.8	2%	0.016	34%	0.34	C	S	.	.	H	α-helix	trans	-64.9	-35.2	177.9	-74	-4.2	0	0	0	112.2	L33 L39 V40 F41 V83 W86 A87 T284 M287	L33-Y37 HydrophobicContact CB-CD2 4.39Å; L33-Y37 HydrophobicContact CB-CE2 4.11Å; L33-Y37 HydrophobicContact CD2-CE1 4.25Å; L33-Y37 VanDerWaalsContact O-CB 3.3Å; L33-Y37 WeakPolarHBondContact O-CB 3.41Å; L33-Y37 PolarHBondContact O-N 3.43Å; Y37-L39 VanDerWaalsContact C-N 3.34Å; Y37-L39 PolarHBondContact O-N 3.17Å; Y37-V40 PolarHBondContact O-N 3.45Å; Y37-F41 WeakPolarHBondContact O-CB 3.46Å; Y37-F41 PolarHBondContact O-N 2.86Å; Y37-V83 HydrophobicContact CG-CG1 4.04Å; Y37-V83 VanDerWaalsContact O-CG1 3.32Å; Y37-V83 WeakPolarHBondContact O-CG1 3.2Å; Y37-W86 HydrophobicContact CD2-CB 4.27Å; Y37-W86 HydrophobicContact CE2-CB 4.12Å; Y37-A87 HydrophobicContact CD2-CB 4.09Å; Y37-A87 HydrophobicContact CG-CB 4.47Å; Y37-T284 HydrophobicContact CE1-CG2 3.94Å; Y37-T284 PolarHBondContact OH-OG1 3.36Å; Y37-M287 HydrophobicContact CE1-CB 4.22Å; Y37-M287 HydrophobicContact CE1-SD 3.7Å; Y37-M287 HydrophobicContact CE2-SD 3.88Å; Y37-M287 PolarHBondContact OH-SD 3.36Å
38	S	95.3	Very high	93.1	Very high	60 Å²	60	60.4 Å²	60.4	42%	0.42	31%	0.314	S	S	.	.	H	α-helix	trans	-61.6	-43	172.1	-59.1	0	0	0	0	111.5	P34 P35 L36 F41 I42	P34-S38 WeakPolarHBondContact O-CB 3.15Å; P34-S38 PolarHBondContact O-N 3.37Å; P34-S38 PolarHBondContact O-OG 3.28Å; P35-S38 PolarHBondContact O-N 3.08Å; L36-S38 VanDerWaalsContact C-N 3.31Å; L36-S38 PolarHBondContact O-N 3.27Å; S38-F41 PolarHBondContact O-N 2.83Å; S38-I42 VanDerWaalsContact O-CG1 3.3Å; S38-I42 WeakPolarHBondContact O-CG1 3.38Å; S38-I42 PolarHBondContact O-N 3.42Å
39	L	95.6	Very high	93.7	Very high	88 Å²	88	58.1 Å²	58.1	46%	0.461	30%	0.302	S	S	.	.	H	α-helix	trans	-65.2	-44.1	176.6	-167.6	67.9	0	0	0	112.1	P35 L36 Y37 F41 I42 F43	P35-L39 PolarHBondContact O-N 3.03Å; L36-L39 WeakPolarHBondContact O-CB 3.39Å; L36-L39 PolarHBondContact O-N 2.9Å; L36-L39 VanDerWaalsContact O-N 3.17Å; Y37-L39 VanDerWaalsContact C-N 3.34Å; Y37-L39 PolarHBondContact O-N 3.17Å; L39-F41 VanDerWaalsContact C-N 3.31Å; L39-F41 PolarHBondContact O-N 2.89Å; L39-I42 PolarHBondContact O-N 2.87Å; L39-F43 HydrophobicContact CD1-CD2 3.82Å; L39-F43 HydrophobicContact CD1-CE2 3.24Å; L39-F43 HydrophobicContact CD1-CZ 3.94Å; L39-F43 HydrophobicContact CD2-CD2 4.48Å; L39-F43 HydrophobicContact CD2-CE2 4.04Å; L39-F43 HydrophobicContact CG-CD2 3.69Å; L39-F43 HydrophobicContact CG-CE2 3.49Å; L39-F43 VanDerWaalsContact CG-CE2 3.49Å; L39-F43 WeakPolarHBondContact O-CD2 3.47Å; L39-F43 PolarHBondContact O-N 3.44Å
40	V	95.9	Very high	94.1	Very high	7 Å²	7	59 Å²	59	4%	0.042	31%	0.305	C	S	.	.	H	α-helix	trans	-59.3	-44.1	174.7	170.9	0	0	0	0	110.5	L36 Y37 G44 L80 T288	L36-V40 VanDerWaalsContact O-CG2 3.32Å; L36-V40 WeakPolarHBondContact O-CG2 3.49Å; L36-V40 PolarHBondContact O-N 3.18Å; Y37-V40 PolarHBondContact O-N 3.45Å; V40-G44 WeakPolarHBondContact O-CA 3.41Å; V40-G44 PolarHBondContact O-N 3.26Å; V40-L80 HydrophobicContact CG1-CD2 4.26Å; V40-T288 HydrophobicContact CG2-CG2 3.74Å
41	F	96.7	Very high	94.5	Very high	60 Å²	60	57.8 Å²	57.8	26%	0.263	29%	0.294	S	S	.	.	H	α-helix	trans	-61	-49.9	177.2	178.9	-103.5	0	0	0	111.7	Y37 S38 L39 F45 L80 V83 P84	Y37-F41 WeakPolarHBondContact O-CB 3.46Å; Y37-F41 PolarHBondContact O-N 2.86Å; S38-F41 PolarHBondContact O-N 2.83Å; L39-F41 VanDerWaalsContact C-N 3.31Å; L39-F41 PolarHBondContact O-N 2.89Å; F41-F45 HydrophobicContact CE2-CD2 4.35Å; F41-F45 HydrophobicContact CZ-CD2 4.32Å; F41-F45 WeakPolarHBondContact O-CB 3.38Å; F41-F45 PolarHBondContact O-N 3.38Å; F41-L80 HydrophobicContact CD2-CB 4.5Å; F41-L80 WeakPolarHBondContact CD2-O 3.39Å; F41-V83 HydrophobicContact CB-CG1 4.35Å; F41-P84 HydrophobicContact CD1-CG 4.33Å; F41-P84 HydrophobicContact CD2-CG 3.67Å; F41-P84 HydrophobicContact CE1-CG 4.45Å; F41-P84 HydrophobicContact CE2-CG 3.82Å; F41-P84 HydrophobicContact CG-CG 3.94Å; F41-P84 HydrophobicContact CZ-CG 4.21Å
42	I	96	Very high	94.7	Very high	96 Å²	96	48.7 Å²	48.7	49%	0.492	26%	0.261	S	S	.	.	H	α-helix	trans	-60.4	-54.6	-178.7	-68.3	165.1	0	0	0	111	S38 L39 V46	S38-I42 VanDerWaalsContact O-CG1 3.3Å; S38-I42 WeakPolarHBondContact O-CG1 3.38Å; S38-I42 PolarHBondContact O-N 3.42Å; L39-I42 PolarHBondContact O-N 2.87Å; I42-V46 WeakPolarHBondContact O-CB 3.41Å; I42-V46 VanDerWaalsContact O-CG2 3.3Å; I42-V46 WeakPolarHBondContact O-CG2 2.95Å; I42-V46 PolarHBondContact O-N 3.1Å; I42-V46 VanDerWaalsContact O-N 3.11Å
43	F	95	Very high	94.7	Very high	125 Å²	125	47.4 Å²	47.4	55%	0.548	25%	0.254	S	S	.	.	H	α-helix	trans	-68.9	-39.9	-177.9	-70.5	-49.7	0	0	0	112.4	L39 G47 C291	L39-F43 HydrophobicContact CD1-CD2 3.82Å; L39-F43 HydrophobicContact CD1-CE2 3.24Å; L39-F43 HydrophobicContact CD1-CZ 3.94Å; L39-F43 HydrophobicContact CD2-CD2 4.48Å; L39-F43 HydrophobicContact CD2-CE2 4.04Å; L39-F43 HydrophobicContact CG-CD2 3.69Å; L39-F43 HydrophobicContact CG-CE2 3.49Å; L39-F43 VanDerWaalsContact CG-CE2 3.49Å; L39-F43 WeakPolarHBondContact O-CD2 3.47Å; L39-F43 PolarHBondContact O-N 3.44Å; F43-G47 WeakPolarHBondContact O-CA 3.22Å; F43-G47 PolarHBondContact O-N 3.48Å; F43-C291 HydrophobicContact CB-CB 4.42Å
44	G	95.8	Very high	94.6	Very high	0 Å²	0	47 Å²	47	0%	0	25%	0.252	C	S	.	.	H	α-helix	trans	-64.7	-45.3	178.4	0	0	0	0	0	111.9	V40 N48 L80 C291	V40-G44 WeakPolarHBondContact O-CA 3.41Å; V40-G44 PolarHBondContact O-N 3.26Å; G44-N48 VanDerWaalsContact O-CB 3.29Å; G44-N48 WeakPolarHBondContact O-CB 3.42Å; G44-N48 PolarHBondContact O-N 3.36Å; G44-N48 PolarHBondContact O-ND2 3.41Å; G44-L80 WeakPolarHBondContact O-CD1 3.44Å; G44-C291 VanDerWaalsContact CA-CB 3.47Å
45	F	96.4	Very high	94.3	Very high	75 Å²	75	46 Å²	46	33%	0.329	25%	0.245	S	C	.	.	H	α-helix	trans	-65.9	-51.6	-179.2	-172.5	-92.4	0	0	0	111.1	F41 G47 M49 L77	F41-F45 HydrophobicContact CE2-CD2 4.35Å; F41-F45 HydrophobicContact CZ-CD2 4.32Å; F41-F45 WeakPolarHBondContact O-CB 3.38Å; F41-F45 PolarHBondContact O-N 3.38Å; F45-G47 PolarHBondContact O-N 3.14Å; F45-M49 HydrophobicContact CD1-CG 4.19Å; F45-M49 HydrophobicContact CD2-CE 4.35Å; F45-M49 HydrophobicContact CE1-CE 4.3Å; F45-M49 HydrophobicContact CE1-CG 3.98Å; F45-M49 HydrophobicContact CE2-CE 3.56Å; F45-M49 HydrophobicContact CE2-CG 4.49Å; F45-M49 HydrophobicContact CZ-CE 3.53Å; F45-M49 HydrophobicContact CZ-CG 4.14Å; F45-M49 VanDerWaalsContact O-CB 3.25Å; F45-M49 WeakPolarHBondContact O-CB 3.4Å; F45-M49 WeakPolarHBondContact O-CG 3.2Å; F45-M49 PolarHBondContact O-N 3.22Å; F45-L77 HydrophobicContact CD2-CD2 3.96Å; F45-L77 HydrophobicContact CE2-CD2 4.38Å
46	V	95.1	Very high	94.1	Very high	93 Å²	93	46.4 Å²	46.4	56%	0.564	24%	0.243	S	C	*	.	H	α-helix	trans	-61.8	-44.8	179	175.2	0	0	0	0	110.9	I42 L50	I42-V46 WeakPolarHBondContact O-CB 3.41Å; I42-V46 VanDerWaalsContact O-CG2 3.3Å; I42-V46 WeakPolarHBondContact O-CG2 2.95Å; I42-V46 PolarHBondContact O-N 3.1Å; I42-V46 VanDerWaalsContact O-N 3.11Å; V46-L50 WeakPolarHBondContact O-CB 3.49Å; V46-L50 PolarHBondContact O-N 3.32Å
47	G	94.2	Very high	93.6	Very high	14 Å²	14	46.8 Å²	46.8	14%	0.144	25%	0.25	C	S	.	.	H	α-helix	trans	-62.7	-51.6	-179.5	0	0	0	0	0	112.7	F43 F45 L50 V51 P294	F43-G47 WeakPolarHBondContact O-CA 3.22Å; F43-G47 PolarHBondContact O-N 3.48Å; F45-G47 PolarHBondContact O-N 3.14Å; G47-L50 PolarHBondContact O-N 2.99Å; G47-V51 WeakPolarHBondContact O-CG2 3.31Å; G47-V51 PolarHBondContact O-N 2.84Å; G47-P294 VanDerWaalsContact C-CG 3.43Å
48	N	96.1	Very high	93	Very high	0 Å²	0	48.5 Å²	48.5	0%	0	26%	0.262	C	S	.	.	H	α-helix	trans	-69.6	-36.3	-178.5	-74.1	-63.1	0	0	0	112.2	G44 L50 V51 I52 L77 C290	G44-N48 VanDerWaalsContact O-CB 3.29Å; G44-N48 WeakPolarHBondContact O-CB 3.42Å; G44-N48 PolarHBondContact O-N 3.36Å; G44-N48 PolarHBondContact O-ND2 3.41Å; N48-L50 VanDerWaalsContact C-N 3.34Å; N48-L50 PolarHBondContact O-N 3.46Å; N48-V51 WeakPolarHBondContact O-CB 3.37Å; N48-V51 PolarHBondContact O-N 3.14Å; N48-I52 WeakPolarHBondContact O-CG1 3.24Å; N48-I52 PolarHBondContact O-N 2.71Å; N48-L77 HydrophobicContact CB-CD2 3.97Å; N48-L77 HydrophobicContact CB-CG 4.09Å; N48-C290 PolarHBondContact ND2-O 2.92Å
49	M	95.2	Very high	92.4	Very high	67 Å²	67	47.4 Å²	47.4	33%	0.33	25%	0.25	S	C	.	.	H	α-helix	trans	-61.7	-42	171.9	-73.7	-62.2	179.7	0	0	111.9	F45 V51 I52 L53 L77	F45-M49 HydrophobicContact CD1-CG 4.19Å; F45-M49 HydrophobicContact CD2-CE 4.35Å; F45-M49 HydrophobicContact CE1-CE 4.3Å; F45-M49 HydrophobicContact CE1-CG 3.98Å; F45-M49 HydrophobicContact CE2-CE 3.56Å; F45-M49 HydrophobicContact CE2-CG 4.49Å; F45-M49 HydrophobicContact CZ-CE 3.53Å; F45-M49 HydrophobicContact CZ-CG 4.14Å; F45-M49 VanDerWaalsContact O-CB 3.25Å; F45-M49 WeakPolarHBondContact O-CB 3.4Å; F45-M49 WeakPolarHBondContact O-CG 3.2Å; F45-M49 PolarHBondContact O-N 3.22Å; M49-V51 VanDerWaalsContact C-N 3.33Å; M49-V51 PolarHBondContact O-N 2.91Å; M49-I52 PolarHBondContact O-N 3.43Å; M49-I52 HydrophobicContact SD-CD1 4.5Å; M49-L53 WeakPolarHBondContact O-CB 3.36Å; M49-L53 VanDerWaalsContact O-CG 3.31Å; M49-L53 WeakPolarHBondContact O-CG 3.42Å; M49-L53 PolarHBondContact O-N 3.34Å; M49-L77 HydrophobicContact CE-CD1 3.5Å; M49-L77 HydrophobicContact CE-CD2 3.94Å; M49-L77 HydrophobicContact CE-CG 4.38Å; M49-L77 HydrophobicContact CG-CD2 4.38Å; M49-L77 HydrophobicContact SD-CD1 3.84Å
50	L	92.3	Very high	92	Very high	35 Å²	35	51.7 Å²	51.7	18%	0.183	26%	0.26	C	S	.	.	H	α-helix	trans	-62.3	-40.8	175.4	-176.9	62.4	0	0	0	111.8	V46 G47 N48 L53 I54 L308 F311	V46-L50 WeakPolarHBondContact O-CB 3.49Å; V46-L50 PolarHBondContact O-N 3.32Å; G47-L50 PolarHBondContact O-N 2.99Å; N48-L50 VanDerWaalsContact C-N 3.34Å; N48-L50 PolarHBondContact O-N 3.46Å; L50-L53 PolarHBondContact O-N 3.4Å; L50-I54 HydrophobicContact CD1-CD1 4.02Å; L50-I54 HydrophobicContact CD1-CG1 4.3Å; L50-I54 HydrophobicContact CG-CD1 3.87Å; L50-I54 WeakPolarHBondContact O-CB 3.3Å; L50-I54 VanDerWaalsContact O-CG1 3.31Å; L50-I54 WeakPolarHBondContact O-CG1 3.39Å; L50-I54 PolarHBondContact O-N 3.4Å; L50-L308 HydrophobicContact CD2-CD1 3.82Å; L50-L308 HydrophobicContact CD2-CG 4.36Å; L50-F311 HydrophobicContact CD1-CD1 3.89Å; L50-F311 HydrophobicContact CD1-CE1 3.76Å; L50-F311 HydrophobicContact CD1-CZ 4.43Å
51	V	92.8	Very high	91.6	Very high	2 Å²	2	53.4 Å²	53.4	1%	0.012	27%	0.268	C	S	.	.	H	α-helix	trans	-58.5	-49.5	174.6	171.9	0	0	0	0	110.8	G47 N48 M49 L53 I54 L55 A73 P294 Y297 F304	G47-V51 WeakPolarHBondContact O-CG2 3.31Å; G47-V51 PolarHBondContact O-N 2.84Å; N48-V51 WeakPolarHBondContact O-CB 3.37Å; N48-V51 PolarHBondContact O-N 3.14Å; M49-V51 VanDerWaalsContact C-N 3.33Å; M49-V51 PolarHBondContact O-N 2.91Å; V51-L53 PolarHBondContact O-N 3.23Å; V51-I54 PolarHBondContact O-N 2.87Å; V51-L55 HydrophobicContact CG1-CD1 3.73Å; V51-L55 HydrophobicContact CG1-CG 4.29Å; V51-L55 WeakPolarHBondContact O-CB 3.23Å; V51-L55 VanDerWaalsContact O-CG 3.24Å; V51-L55 WeakPolarHBondContact O-CG 3.37Å; V51-L55 PolarHBondContact O-N 2.78Å; V51-A73 HydrophobicContact CB-CB 4.47Å; V51-A73 HydrophobicContact CG1-CB 4.06Å; V51-P294 HydrophobicContact CG2-CB 4.07Å; V51-P294 HydrophobicContact CG2-CG 4.17Å; V51-Y297 HydrophobicContact CG1-CD2 4.27Å; V51-Y297 HydrophobicContact CG1-CE2 4.15Å; V51-Y297 HydrophobicContact CG2-CD2 3.72Å; V51-Y297 HydrophobicContact CG2-CE2 4.18Å; V51-F304 HydrophobicContact CB-CE2 4.4Å; V51-F304 HydrophobicContact CB-CZ 4.44Å; V51-F304 HydrophobicContact CG1-CE2 4.49Å; V51-F304 HydrophobicContact CG2-CE2 3.96Å; V51-F304 HydrophobicContact CG2-CZ 3.65Å
52	I	94.5	Very high	91.2	Very high	23 Å²	23	58 Å²	58	12%	0.118	29%	0.288	C	S	.	.	H	α-helix	trans	-58.2	-48.7	178	-68.5	170.7	0	0	0	110.8	N48 M49 I54 L55 I56 L70 A73 I74 L77	N48-I52 WeakPolarHBondContact O-CG1 3.24Å; N48-I52 PolarHBondContact O-N 2.71Å; M49-I52 PolarHBondContact O-N 3.43Å; M49-I52 HydrophobicContact SD-CD1 4.5Å; I52-I54 PolarHBondContact O-N 3.46Å; I52-L55 PolarHBondContact O-N 2.75Å; I52-I56 HydrophobicContact CG2-CD1 3.68Å; I52-I56 HydrophobicContact CG2-CG1 4.49Å; I52-I56 WeakPolarHBondContact O-CG1 3.21Å; I52-I56 PolarHBondContact O-N 3.05Å; I52-L70 HydrophobicContact CB-CD1 4.27Å; I52-L70 HydrophobicContact CG1-CD1 4Å; I52-L70 HydrophobicContact CG2-CD1 3.94Å; I52-A73 HydrophobicContact CD1-CB 4.24Å; I52-A73 HydrophobicContact CG1-CB 3.8Å; I52-I74 HydrophobicContact CD1-CG1 4.18Å; I52-L77 HydrophobicContact CD1-CD1 3.38Å; I52-L77 HydrophobicContact CD1-CG 4.43Å
53	L	91.5	Very high	90.8	Very high	82 Å²	82	55.2 Å²	55.2	43%	0.429	28%	0.277	S	S	.	.	H	α-helix	trans	-59.9	-43.5	179.8	-73.3	172.1	0	0	0	112.4	M49 L50 V51 S57 F311	M49-L53 WeakPolarHBondContact O-CB 3.36Å; M49-L53 VanDerWaalsContact O-CG 3.31Å; M49-L53 WeakPolarHBondContact O-CG 3.42Å; M49-L53 PolarHBondContact O-N 3.34Å; L50-L53 PolarHBondContact O-N 3.4Å; V51-L53 PolarHBondContact O-N 3.23Å; L53-S57 WeakPolarHBondContact O-CB 3.48Å; L53-S57 PolarHBondContact O-N 2.86Å; L53-S57 PolarHBondContact O-OG 3.46Å; L53-F311 HydrophobicContact CD1-CZ 4.39Å
54	I	88.3	Confident	90.6	Very high	0 Å²	0	50.2 Å²	50.2	0%	0	26%	0.256	C	S	.	.	I	π-helix	trans	-65.7	-42.8	177.4	-72.6	169.5	0	0	0	110.9	L50 V51 I52 C58 K59 F304 Y307 L308	L50-I54 HydrophobicContact CD1-CD1 4.02Å; L50-I54 HydrophobicContact CD1-CG1 4.3Å; L50-I54 HydrophobicContact CG-CD1 3.87Å; L50-I54 WeakPolarHBondContact O-CB 3.3Å; L50-I54 VanDerWaalsContact O-CG1 3.31Å; L50-I54 WeakPolarHBondContact O-CG1 3.39Å; L50-I54 PolarHBondContact O-N 3.4Å; V51-I54 PolarHBondContact O-N 2.87Å; I52-I54 PolarHBondContact O-N 3.46Å; I54-C58 HydrophobicContact CG2-CB 4.35Å; I54-C58 WeakPolarHBondContact O-CA 3.47Å; I54-C58 VanDerWaalsContact O-CB 3.28Å; I54-C58 WeakPolarHBondContact O-CB 3.28Å; I54-C58 PolarHBondContact O-N 3.32Å; I54-K59 PolarHBondContact O-N 2.87Å; I54-F304 HydrophobicContact CB-CE2 4.15Å; I54-F304 HydrophobicContact CD1-CE1 4.27Å; I54-F304 HydrophobicContact CD1-CE2 3.74Å; I54-F304 HydrophobicContact CD1-CZ 3.6Å; I54-F304 HydrophobicContact CG2-CD2 4.16Å; I54-F304 HydrophobicContact CG2-CE2 3.97Å; I54-Y307 HydrophobicContact CG2-CG 4.35Å; I54-L308 HydrophobicContact CD1-CB 4.07Å; I54-L308 HydrophobicContact CD1-CG 4.42Å
55	L	89.5	Confident	90.4	Very high	2 Å²	2	51.1 Å²	51.1	1%	0.01	26%	0.261	C	S	.	.	I	π-helix	trans	-63.7	-43.1	-179.6	-73.4	173.6	0	0	0	112	V51 I52 K59 R60 L61 D66 L69 L70	V51-L55 HydrophobicContact CG1-CD1 3.73Å; V51-L55 HydrophobicContact CG1-CG 4.29Å; V51-L55 WeakPolarHBondContact O-CB 3.23Å; V51-L55 VanDerWaalsContact O-CG 3.24Å; V51-L55 WeakPolarHBondContact O-CG 3.37Å; V51-L55 PolarHBondContact O-N 2.78Å; I52-L55 PolarHBondContact O-N 2.75Å; L55-K59 HydrophobicContact CD2-CD 3.76Å; L55-K59 CarbonylContact O-C 3.51Å; L55-R60 PolarHBondContact O-N 3.48Å; L55-L61 HydrophobicContact CB-CD2 3.93Å; L55-L61 PolarHBondContact O-N 3.41Å; L55-D66 HydrophobicContact CD2-CB 4.25Å; L55-L69 HydrophobicContact CD1-CB 3.95Å; L55-L69 HydrophobicContact CD2-CB 4.45Å; L55-L70 HydrophobicContact CD1-CB 4.05Å; L55-L70 HydrophobicContact CD1-CD1 4.5Å
56	I	90.1	Very high	90.2	Very high	86 Å²	86	48.2 Å²	48.2	44%	0.441	25%	0.249	S	C	.	.	I	π-helix	trans	-75.7	-52.4	179.9	-64.3	173.1	0	0	0	110.9	I52 R60 L61 L70	I52-I56 HydrophobicContact CG2-CD1 3.68Å; I52-I56 HydrophobicContact CG2-CG1 4.49Å; I52-I56 WeakPolarHBondContact O-CG1 3.21Å; I52-I56 PolarHBondContact O-N 3.05Å; I56-R60 WeakPolarHBondContact O-CA 3.41Å; I56-R60 PolarHBondContact O-N 3.49Å; I56-L61 HydrophobicContact CG1-CD1 4.33Å; I56-L70 HydrophobicContact CD1-CD1 4.36Å; I56-L70 HydrophobicContact CG1-CD1 4.35Å
57	S	84	Confident	90.2	Very high	64 Å²	64	44.4 Å²	44.4	45%	0.448	23%	0.226	S	C	.	.	I	π-helix	trans	-82.6	-41.3	-168.5	-51.9	0	0	0	0	113.3	L53	L53-S57 WeakPolarHBondContact O-CB 3.48Å; L53-S57 PolarHBondContact O-N 2.86Å; L53-S57 PolarHBondContact O-OG 3.46Å
58	C	83.1	Confident	90.2	Very high	39 Å²	39	44 Å²	44	26%	0.264	22%	0.22	S	C	.	.	I	π-helix	trans	-95	-47.6	-174	-56.6	0	0	0	0	111.8	I54 Y307	I54-C58 HydrophobicContact CG2-CB 4.35Å; I54-C58 WeakPolarHBondContact O-CA 3.47Å; I54-C58 VanDerWaalsContact O-CB 3.28Å; I54-C58 WeakPolarHBondContact O-CB 3.28Å; I54-C58 PolarHBondContact O-N 3.32Å; C58-Y307 HydrophobicContact CB-CD1 3.69Å; C58-Y307 HydrophobicContact CB-CE1 4.3Å; C58-Y307 HydrophobicContact CB-CG 4.25Å
59	K	82.6	Confident	90.1	Very high	37 Å²	37	44.8 Å²	44.8	16%	0.161	22%	0.224	C	C	.	.	I	π-helix	trans	-86.8	-22.5	-177.8	-75.7	-179.9	137.4	-158.2	0	114.1	I54 L55 L61 D66 Y307	I54-K59 PolarHBondContact O-N 2.87Å; L55-K59 HydrophobicContact CD2-CD 3.76Å; L55-K59 CarbonylContact O-C 3.51Å; K59-L61 PolarHBondContact O-N 2.67Å; K59-D66 IonicContact NZ-OD1 3.85Å; K59-D66 PolarHBondContact NZ-OD1 3.21Å; K59-Y307 HydrophobicContact CD-CD2 4.21Å; K59-Y307 HydrophobicContact CD-CE2 4.06Å; K59-Y307 HydrophobicContact CG-CD2 3.89Å; K59-Y307 HydrophobicContact CG-CE1 4.36Å; K59-Y307 HydrophobicContact CG-CE2 3.58Å; K59-Y307 HydrophobicContact CG-CG 4.44Å
60	R	87.1	Confident	90.2	Very high	179 Å²	179	42.7 Å²	42.7	68%	0.675	21%	0.214	S	C	*	.	T	Hydrogen-bonded Turn	trans	54.4	32.4	179.4	-54.1	-175.2	-177.5	179.9	0	113.8	L55 I56 K62	L55-R60 PolarHBondContact O-N 3.48Å; I56-R60 WeakPolarHBondContact O-CA 3.41Å; I56-R60 PolarHBondContact O-N 3.49Å; R60-K62 HydrophobicContact CB-CG 4.37Å; R60-K62 PolarHBondContact O-N 2.83Å
61	L	87.9	Confident	90.4	Very high	42 Å²	42	42 Å²	42	22%	0.22	21%	0.21	C	C	.	.	T	Hydrogen-bonded Turn	trans	47.1	39.9	172.4	-55.8	175	0	0	0	115.2	L55 I56 K59 S63 D66 I67 L70	L55-L61 HydrophobicContact CB-CD2 3.93Å; L55-L61 PolarHBondContact O-N 3.41Å; I56-L61 HydrophobicContact CG1-CD1 4.33Å; K59-L61 PolarHBondContact O-N 2.67Å; L61-S63 PolarHBondContact O-N 3.19Å; L61-D66 HydrophobicContact CD2-CB 4.24Å; L61-I67 HydrophobicContact CB-CD1 3.91Å; L61-I67 HydrophobicContact CD1-CD1 4.28Å; L61-I67 HydrophobicContact CG-CD1 4.47Å; L61-L70 HydrophobicContact CD1-CD2 3.79Å; L61-L70 HydrophobicContact CD2-CB 4.19Å; L61-L70 HydrophobicContact CD2-CD2 4.04Å
62	K	86.9	Confident	90.6	Very high	157 Å²	157	41.9 Å²	41.9	68%	0.683	21%	0.21	S	C	*	.			trans	-75.2	-5.8	-172	-65.9	-176	179.9	-172.5	0	114.7	R60	R60-K62 HydrophobicContact CB-CG 4.37Å; R60-K62 PolarHBondContact O-N 2.83Å
63	S	88.6	Confident	90.7	Very high	38 Å²	38	40.9 Å²	40.9	27%	0.266	21%	0.205	S	C	.	.	S	Bend	trans	-136.1	152.1	-176.9	74.9	0	0	0	0	112.1	L61 T65 D66 I67	L61-S63 PolarHBondContact O-N 3.19Å; S63-T65 PolarHBondContact O-N 2.9Å; S63-D66 PolarHBondContact N-OD2 3.09Å; S63-D66 WeakPolarHBondContact O-CB 3.32Å; S63-D66 PolarHBondContact O-N 3.49Å; S63-D66 PolarHBondContact OG-N 2.85Å; S63-D66 PolarHBondContact OG-OD2 2.91Å; S63-I67 PolarHBondContact O-N 3.45Å
64	M	91.6	Very high	91	Very high	19 Å²	19	39.3 Å²	39.3	9%	0.094	20%	0.196	C	C	.	.	H	α-helix	trans	-53.7	-37.5	174.3	-173.5	172.9	-174.5	0	0	112.4	D66 I67 Y68 R140	M64-D66 VanDerWaalsContact C-N 3.34Å; M64-D66 PolarHBondContact O-N 3.03Å; M64-I67 WeakPolarHBondContact O-CB 3.49Å; M64-I67 PolarHBondContact O-N 3.37Å; M64-Y68 HydrophobicContact CE-CE2 3.92Å; M64-Y68 WeakPolarHBondContact CE-OH 3.38Å; M64-Y68 HydrophobicContact CG-CD2 4.45Å; M64-Y68 HydrophobicContact CG-CE2 3.93Å; M64-Y68 PolarHBondContact O-N 2.99Å; M64-Y68 VanDerWaalsContact O-N 3.07Å; M64-R140 HydrophobicContact SD-CB 4Å; M64-R140 HydrophobicContact SD-CG 4.19Å
65	T	90.9	Very high	91.5	Very high	19 Å²	19	39.3 Å²	39.3	12%	0.117	20%	0.196	C	C	.	.	H	α-helix	trans	-62.4	-39.9	174.7	-46	0	0	0	0	112.2	S63 I67 Y68 L69 L122 D125 R126	S63-T65 PolarHBondContact O-N 2.9Å; T65-I67 VanDerWaalsContact C-N 3.3Å; T65-I67 PolarHBondContact O-N 3.26Å; T65-Y68 PolarHBondContact O-N 3.21Å; T65-L69 HydrophobicContact CG2-CD1 4.26Å; T65-L69 VanDerWaalsContact O-CG 3.3Å; T65-L69 WeakPolarHBondContact O-CG 3.44Å; T65-L69 PolarHBondContact O-N 3.41Å; T65-L122 HydrophobicContact CG2-CD2 3.75Å; T65-D125 PolarHBondContact OG1-OD2 3.47Å; T65-R126 PolarHBondContact OG1-NH2 3.44Å
66	D	91.6	Very high	91.9	Very high	14 Å²	14	39.7 Å²	39.7	8%	0.075	20%	0.198	C	C	.	.	H	α-helix	trans	-67.9	-33.2	178.3	-60.6	-49.9	0	0	0	111.1	L55 K59 L61 S63 M64 L70	L55-D66 HydrophobicContact CD2-CB 4.25Å; K59-D66 IonicContact NZ-OD1 3.85Å; K59-D66 PolarHBondContact NZ-OD1 3.21Å; L61-D66 HydrophobicContact CD2-CB 4.24Å; S63-D66 PolarHBondContact N-OD2 3.09Å; S63-D66 WeakPolarHBondContact O-CB 3.32Å; S63-D66 PolarHBondContact O-N 3.49Å; S63-D66 PolarHBondContact OG-N 2.85Å; S63-D66 PolarHBondContact OG-OD2 2.91Å; M64-D66 VanDerWaalsContact C-N 3.34Å; M64-D66 PolarHBondContact O-N 3.03Å; D66-L70 WeakPolarHBondContact O-CB 3.32Å; D66-L70 PolarHBondContact O-N 3.48Å
67	I	95.4	Very high	92.2	Very high	14 Å²	14	36.4 Å²	36.4	7%	0.072	18%	0.181	C	C	.	.	H	α-helix	trans	-63.9	-45.7	172.6	-59.6	-64.6	0	0	0	111	L61 S63 M64 T65 L70 N71 V142	L61-I67 HydrophobicContact CB-CD1 3.91Å; L61-I67 HydrophobicContact CD1-CD1 4.28Å; L61-I67 HydrophobicContact CG-CD1 4.47Å; S63-I67 PolarHBondContact O-N 3.45Å; M64-I67 WeakPolarHBondContact O-CB 3.49Å; M64-I67 PolarHBondContact O-N 3.37Å; T65-I67 VanDerWaalsContact C-N 3.3Å; T65-I67 PolarHBondContact O-N 3.26Å; I67-L70 WeakPolarHBondContact O-CB 3.46Å; I67-L70 PolarHBondContact O-N 3.43Å; I67-N71 PolarHBondContact O-N 3.43Å; I67-N71 PolarHBondContact O-ND2 3.18Å; I67-V142 HydrophobicContact CD1-CG1 4.19Å; I67-V142 HydrophobicContact CG1-CG1 4.2Å
68	Y	95.4	Very high	92.8	Very high	5 Å²	5	36.6 Å²	36.6	2%	0.02	18%	0.175	C	C	.	.	H	α-helix	trans	-67.5	-39.3	178	-64.7	-24.1	0	0	0	113	M64 T65 L70 N71 L72 F118 L121 L122 D125 T148	M64-Y68 HydrophobicContact CE-CE2 3.92Å; M64-Y68 WeakPolarHBondContact CE-OH 3.38Å; M64-Y68 HydrophobicContact CG-CD2 4.45Å; M64-Y68 HydrophobicContact CG-CE2 3.93Å; M64-Y68 PolarHBondContact O-N 2.99Å; M64-Y68 VanDerWaalsContact O-N 3.07Å; T65-Y68 PolarHBondContact O-N 3.21Å; Y68-L70 VanDerWaalsContact C-N 3.29Å; Y68-L70 PolarHBondContact O-N 3.07Å; Y68-N71 PolarHBondContact O-N 2.99Å; Y68-L72 WeakPolarHBondContact O-CB 3.48Å; Y68-L72 PolarHBondContact O-N 3.45Å; Y68-F118 HydrophobicContact CD1-CD1 4.08Å; Y68-F118 HydrophobicContact CD1-CE1 4.23Å; Y68-L121 HydrophobicContact CD1-CD1 4.42Å; Y68-L121 HydrophobicContact CD2-CB 4.02Å; Y68-L121 HydrophobicContact CE1-CB 4.35Å; Y68-L121 HydrophobicContact CE1-CD1 3.91Å; Y68-L121 HydrophobicContact CE2-CB 3.75Å; Y68-L121 HydrophobicContact CG-CB 4.41Å; Y68-L122 HydrophobicContact CD2-CD2 4.31Å; Y68-D125 HydrophobicContact CD2-CB 4.28Å; Y68-D125 HydrophobicContact CE2-CB 4.03Å; Y68-T148 WeakPolarHBondContact CE1-OG1 3.46Å; Y68-T148 PolarHBondContact OH-OG1 3.27Å
69	L	93.7	Very high	93.4	Very high	17 Å²	17	35 Å²	35	9%	0.089	16%	0.163	C	C	.	.	H	α-helix	trans	-62.9	-36.6	173.5	-70.8	171.6	0	0	0	112	L55 T65 A73 L122 Y297	L55-L69 HydrophobicContact CD1-CB 3.95Å; L55-L69 HydrophobicContact CD2-CB 4.45Å; T65-L69 HydrophobicContact CG2-CD1 4.26Å; T65-L69 VanDerWaalsContact O-CG 3.3Å; T65-L69 WeakPolarHBondContact O-CG 3.44Å; T65-L69 PolarHBondContact O-N 3.41Å; L69-A73 PolarHBondContact O-N 2.89Å; L69-A73 VanDerWaalsContact O-N 3.09Å; L69-L122 HydrophobicContact CD2-CD1 3.9Å; L69-L122 HydrophobicContact CD2-CD2 4.23Å; L69-L122 HydrophobicContact CG-CD2 4.14Å; L69-Y297 HydrophobicContact CD2-CE1 3.98Å; L69-Y297 WeakPolarHBondContact CD2-OH 3.38Å
70	L	96.1	Very high	94.1	Very high	23 Å²	23	33.3 Å²	33.3	12%	0.12	16%	0.156	C	C	.	.	H	α-helix	trans	-63.6	-48.9	174.7	177.7	70.5	0	0	0	111	I52 L55 I56 L61 D66 I67 Y68 L72 A73 I74	I52-L70 HydrophobicContact CB-CD1 4.27Å; I52-L70 HydrophobicContact CG1-CD1 4Å; I52-L70 HydrophobicContact CG2-CD1 3.94Å; L55-L70 HydrophobicContact CD1-CB 4.05Å; L55-L70 HydrophobicContact CD1-CD1 4.5Å; I56-L70 HydrophobicContact CD1-CD1 4.36Å; I56-L70 HydrophobicContact CG1-CD1 4.35Å; L61-L70 HydrophobicContact CD1-CD2 3.79Å; L61-L70 HydrophobicContact CD2-CB 4.19Å; L61-L70 HydrophobicContact CD2-CD2 4.04Å; D66-L70 WeakPolarHBondContact O-CB 3.32Å; D66-L70 PolarHBondContact O-N 3.48Å; I67-L70 WeakPolarHBondContact O-CB 3.46Å; I67-L70 PolarHBondContact O-N 3.43Å; Y68-L70 VanDerWaalsContact C-N 3.29Å; Y68-L70 PolarHBondContact O-N 3.07Å; L70-L72 VanDerWaalsContact C-N 3.31Å; L70-L72 PolarHBondContact O-N 3.38Å; L70-A73 PolarHBondContact O-N 3.27Å; L70-I74 HydrophobicContact CD1-CD1 4.47Å; L70-I74 HydrophobicContact CG-CD1 4.08Å; L70-I74 WeakPolarHBondContact O-CG1 3.33Å; L70-I74 PolarHBondContact O-N 3Å
71	N	98	Very high	94.6	Very high	19 Å²	19	28.6 Å²	28.6	10%	0.102	14%	0.143	C	C	.	.	H	α-helix	trans	-66.4	-34.3	180	-75.5	-81.2	0	0	0	112.4	I67 Y68 I74 S75 F118 S149 W153	I67-N71 PolarHBondContact O-N 3.43Å; I67-N71 PolarHBondContact O-ND2 3.18Å; Y68-N71 PolarHBondContact O-N 2.99Å; N71-I74 PolarHBondContact O-N 3.22Å; N71-S75 WeakPolarHBondContact O-CB 3.49Å; N71-S75 PolarHBondContact O-N 2.96Å; N71-F118 HydrophobicContact CB-CD1 3.82Å; N71-F118 HydrophobicContact CB-CD2 3.77Å; N71-F118 HydrophobicContact CB-CE1 3.49Å; N71-F118 VanDerWaalsContact CB-CE1 3.49Å; N71-F118 HydrophobicContact CB-CE2 3.46Å; N71-F118 VanDerWaalsContact CB-CE2 3.46Å; N71-F118 HydrophobicContact CB-CG 3.99Å; N71-F118 HydrophobicContact CB-CZ 3.32Å; N71-S149 PolarHBondContact ND2-OG 3.13Å; N71-W153 PolarHBondContact OD1-NE1 3.3Å
72	L	96.3	Very high	95	Very high	1 Å²	1	26.6 Å²	26.6	1%	0.005	13%	0.133	C	C	.	.	H	α-helix	trans	-61.4	-45.4	172.5	-177.9	58.5	0	0	0	111.3	Y68 L70 I74 S75 D76 G115 F118 I119 L122 Y297	Y68-L72 WeakPolarHBondContact O-CB 3.48Å; Y68-L72 PolarHBondContact O-N 3.45Å; L70-L72 VanDerWaalsContact C-N 3.31Å; L70-L72 PolarHBondContact O-N 3.38Å; L72-I74 VanDerWaalsContact C-N 3.34Å; L72-I74 PolarHBondContact O-N 2.92Å; L72-S75 VanDerWaalsContact O-CB 3.24Å; L72-S75 WeakPolarHBondContact O-CB 3.34Å; L72-S75 PolarHBondContact O-N 3.03Å; L72-D76 PolarHBondContact O-N 2.88Å; L72-G115 WeakPolarHBondContact CD1-O 3.5Å; L72-F118 HydrophobicContact CB-CB 4.15Å; L72-F118 HydrophobicContact CD1-CB 4.35Å; L72-I119 HydrophobicContact CD1-CD1 4.39Å; L72-I119 HydrophobicContact CD1-CG1 4.01Å; L72-I119 HydrophobicContact CD2-CG1 4.04Å; L72-L122 HydrophobicContact CD2-CD1 3.93Å; L72-Y297 WeakPolarHBondContact CD2-OH 3.44Å
73	A	96.8	Very high	95.4	Very high	1 Å²	1	19.1 Å²	19.1	1%	0.008	10%	0.1	C	C	.	.	H	α-helix	trans	-64.1	-36.7	175.5	0	0	0	0	0	112.7	V51 I52 L69 L70 D76 L77	V51-A73 HydrophobicContact CB-CB 4.47Å; V51-A73 HydrophobicContact CG1-CB 4.06Å; I52-A73 HydrophobicContact CD1-CB 4.24Å; I52-A73 HydrophobicContact CG1-CB 3.8Å; L69-A73 PolarHBondContact O-N 2.89Å; L69-A73 VanDerWaalsContact O-N 3.09Å; L70-A73 PolarHBondContact O-N 3.27Å; A73-D76 PolarHBondContact O-N 2.87Å; A73-L77 WeakPolarHBondContact O-CG 3.47Å; A73-L77 PolarHBondContact O-N 2.94Å
74	I	97.9	Very high	95.8	Very high	50 Å²	50	19.8 Å²	19.8	26%	0.256	10%	0.104	S	C	.	.	H	α-helix	trans	-65.4	-40.4	173.6	-66.8	167.1	0	0	0	110.8	I52 L70 N71 L72 L77 F78 W153	I52-I74 HydrophobicContact CD1-CG1 4.18Å; L70-I74 HydrophobicContact CD1-CD1 4.47Å; L70-I74 HydrophobicContact CG-CD1 4.08Å; L70-I74 WeakPolarHBondContact O-CG1 3.33Å; L70-I74 PolarHBondContact O-N 3Å; N71-I74 PolarHBondContact O-N 3.22Å; L72-I74 VanDerWaalsContact C-N 3.34Å; L72-I74 PolarHBondContact O-N 2.92Å; I74-L77 WeakPolarHBondContact O-CB 3.44Å; I74-L77 PolarHBondContact O-N 3.1Å; I74-F78 HydrophobicContact CG2-CE1 4.46Å; I74-F78 HydrophobicContact CG2-CE2 4.24Å; I74-F78 HydrophobicContact CG2-CZ 4.16Å; I74-F78 PolarHBondContact O-N 3.01Å; I74-W153 HydrophobicContact CB-CZ2 4.27Å; I74-W153 HydrophobicContact CG2-CH2 3.99Å; I74-W153 HydrophobicContact CG2-CZ2 3.78Å
75	S	97.9	Very high	96	Very high	0 Å²	0	22 Å²	22	0%	0	11%	0.113	C	C	.	.	H	α-helix	trans	-59.4	-46.4	174.8	-166.5	0	0	0	0	111.9	N71 L72 L77 F78 F79 G111 S114 G115	N71-S75 WeakPolarHBondContact O-CB 3.49Å; N71-S75 PolarHBondContact O-N 2.96Å; L72-S75 VanDerWaalsContact O-CB 3.24Å; L72-S75 WeakPolarHBondContact O-CB 3.34Å; L72-S75 PolarHBondContact O-N 3.03Å; S75-L77 VanDerWaalsContact C-N 3.29Å; S75-L77 PolarHBondContact O-N 3.21Å; S75-F78 PolarHBondContact O-N 3.39Å; S75-F79 PolarHBondContact O-N 2.86Å; S75-F79 VanDerWaalsContact O-N 3.14Å; S75-G111 WeakPolarHBondContact O-CA 3.43Å; S75-G111 PolarHBondContact OG-O 3.44Å; S75-S114 WeakPolarHBondContact CB-OG 3.3Å; S75-S114 PolarHBondContact OG-OG 3.4Å; S75-G115 WeakPolarHBondContact OG-CA 3.05Å; S75-G115 PolarHBondContact OG-N 2.83Å
76	D	97.3	Very high	96.2	Very high	9 Å²	9	22.8 Å²	22.8	5%	0.048	11%	0.114	C	C	.	.	H	α-helix	trans	-62.5	-37.2	175.7	-71.1	-34.3	0	0	0	111.2	L72 A73 F79 L80 C290 N293	L72-D76 PolarHBondContact O-N 2.88Å; A73-D76 PolarHBondContact O-N 2.87Å; D76-F79 WeakPolarHBondContact O-CB 3.25Å; D76-F79 PolarHBondContact O-N 3.34Å; D76-L80 WeakPolarHBondContact O-CB 3.2Å; D76-L80 WeakPolarHBondContact O-CD1 3.43Å; D76-L80 WeakPolarHBondContact O-CG 3.13Å; D76-L80 PolarHBondContact O-N 2.95Å; D76-C290 HydrophobicContact CB-CB 4.4Å; D76-N293 PolarHBondContact OD2-ND2 3.29Å
77	L	97.6	Very high	96.3	Very high	17 Å²	17	22.4 Å²	22.4	9%	0.089	11%	0.113	C	C	.	.	H	α-helix	trans	-65	-43.3	174.7	-73.6	177.8	0	0	0	112.9	F45 N48 M49 I52 A73 I74 S75 F79 L80 L81	F45-L77 HydrophobicContact CD2-CD2 3.96Å; F45-L77 HydrophobicContact CE2-CD2 4.38Å; N48-L77 HydrophobicContact CB-CD2 3.97Å; N48-L77 HydrophobicContact CB-CG 4.09Å; M49-L77 HydrophobicContact CE-CD1 3.5Å; M49-L77 HydrophobicContact CE-CD2 3.94Å; M49-L77 HydrophobicContact CE-CG 4.38Å; M49-L77 HydrophobicContact CG-CD2 4.38Å; M49-L77 HydrophobicContact SD-CD1 3.84Å; I52-L77 HydrophobicContact CD1-CD1 3.38Å; I52-L77 HydrophobicContact CD1-CG 4.43Å; A73-L77 WeakPolarHBondContact O-CG 3.47Å; A73-L77 PolarHBondContact O-N 2.94Å; I74-L77 WeakPolarHBondContact O-CB 3.44Å; I74-L77 PolarHBondContact O-N 3.1Å; S75-L77 VanDerWaalsContact C-N 3.29Å; S75-L77 PolarHBondContact O-N 3.21Å; L77-F79 VanDerWaalsContact C-N 3.25Å; L77-F79 PolarHBondContact O-N 3.24Å; L77-L80 HydrophobicContact CD2-CD1 4.25Å; L77-L80 PolarHBondContact O-N 3.31Å; L77-L81 VanDerWaalsContact O-CG 3.28Å; L77-L81 WeakPolarHBondContact O-CG 3.38Å; L77-L81 PolarHBondContact O-N 3.07Å
78	F	96.8	Very high	96.2	Very high	69 Å²	69	25.1 Å²	25.1	30%	0.303	13%	0.125	S	C	.	.	H	α-helix	trans	-58.8	-40.5	174.5	-73.5	-17.3	0	0	0	111.9	I74 S75 L81 L107 I110 W153	I74-F78 HydrophobicContact CG2-CE1 4.46Å; I74-F78 HydrophobicContact CG2-CE2 4.24Å; I74-F78 HydrophobicContact CG2-CZ 4.16Å; I74-F78 PolarHBondContact O-N 3.01Å; S75-F78 PolarHBondContact O-N 3.39Å; F78-L81 HydrophobicContact CD1-CD1 4.47Å; F78-L107 HydrophobicContact CB-CD2 4.48Å; F78-L107 HydrophobicContact CD1-CD2 4.43Å; F78-L107 HydrophobicContact CG-CD2 4.35Å; F78-I110 HydrophobicContact CD2-CG2 4.06Å; F78-W153 AromaticContact CD2-CH2 3.53Å; F78-W153 HydrophobicContact CD2-CH2 3.53Å; F78-W153 AromaticContact CD2-CZ3 3.55Å; F78-W153 HydrophobicContact CD2-CZ3 3.55Å; F78-W153 HydrophobicContact CE2-CE3 4.33Å; F78-W153 AromaticContact CE2-CH2 3.42Å; F78-W153 HydrophobicContact CE2-CH2 3.42Å; F78-W153 VanDerWaalsContact CE2-CH2 3.42Å; F78-W153 HydrophobicContact CE2-CZ2 4.34Å; F78-W153 AromaticContact CE2-CZ3 3.42Å; F78-W153 HydrophobicContact CE2-CZ3 3.42Å; F78-W153 VanDerWaalsContact CE2-CZ3 3.42Å
79	F	95.9	Very high	96.1	Very high	5 Å²	5	28 Å²	28	2%	0.022	14%	0.137	C	C	.	.	H	α-helix	trans	-63.4	-49.3	173.8	-164.8	-86	0	0	0	111.4	S75 D76 L77 L81 T82 V83 Y108 F112 W248 M287 C290	S75-F79 PolarHBondContact O-N 2.86Å; S75-F79 VanDerWaalsContact O-N 3.14Å; D76-F79 WeakPolarHBondContact O-CB 3.25Å; D76-F79 PolarHBondContact O-N 3.34Å; L77-F79 VanDerWaalsContact C-N 3.25Å; L77-F79 PolarHBondContact O-N 3.24Å; F79-L81 VanDerWaalsContact C-N 3.32Å; F79-L81 PolarHBondContact O-N 3.18Å; F79-T82 PolarHBondContact O-N 3.49Å; F79-T82 PolarHBondContact O-OG1 3.45Å; F79-V83 HydrophobicContact CD1-CG2 4.32Å; F79-V83 HydrophobicContact CE1-CG2 4.44Å; F79-Y108 HydrophobicContact CD2-CD2 4.05Å; F79-Y108 HydrophobicContact CD2-CE2 4.35Å; F79-Y108 HydrophobicContact CE1-CE2 4.43Å; F79-Y108 AromaticContact CE2-CD2 3.4Å; F79-Y108 HydrophobicContact CE2-CD2 3.4Å; F79-Y108 VanDerWaalsContact CE2-CD2 3.4Å; F79-Y108 AromaticContact CE2-CE2 3.29Å; F79-Y108 HydrophobicContact CE2-CE2 3.29Å; F79-Y108 HydrophobicContact CE2-CG 4.13Å; F79-Y108 AromaticContact CE2-CZ 3.89Å; F79-Y108 AromaticContact CZ-CD2 3.74Å; F79-Y108 HydrophobicContact CZ-CD2 3.74Å; F79-Y108 AromaticContact CZ-CE2 3.35Å; F79-Y108 HydrophobicContact CZ-CE2 3.35Å; F79-F112 HydrophobicContact CE2-CB 4.5Å; F79-W248 HydrophobicContact CE2-CH2 4.09Å; F79-W248 HydrophobicContact CE2-CZ2 4.2Å; F79-W248 AromaticContact CZ-CH2 3.99Å; F79-W248 HydrophobicContact CZ-CH2 3.99Å; F79-W248 HydrophobicContact CZ-CZ2 4.08Å; F79-M287 HydrophobicContact CE1-CB 4.14Å; F79-M287 HydrophobicContact CE1-CG 4.03Å; F79-M287 HydrophobicContact CZ-CB 4.4Å; F79-M287 HydrophobicContact CZ-CG 3.91Å; F79-C290 HydrophobicContact CD1-CB 4Å
80	L	97.2	Very high	95.9	Very high	1 Å²	1	28.2 Å²	28.2	1%	0.005	14%	0.141	C	C	.	.	H	α-helix	trans	-59.9	-36.4	-179.4	-78.6	161.1	0	0	0	113.4	V40 F41 G44 D76 L77 T82 V83 P84 C290	V40-L80 HydrophobicContact CG1-CD2 4.26Å; F41-L80 HydrophobicContact CD2-CB 4.5Å; F41-L80 WeakPolarHBondContact CD2-O 3.39Å; G44-L80 WeakPolarHBondContact O-CD1 3.44Å; D76-L80 WeakPolarHBondContact O-CB 3.2Å; D76-L80 WeakPolarHBondContact O-CD1 3.43Å; D76-L80 WeakPolarHBondContact O-CG 3.13Å; D76-L80 PolarHBondContact O-N 2.95Å; L77-L80 HydrophobicContact CD2-CD1 4.25Å; L77-L80 PolarHBondContact O-N 3.31Å; L80-T82 PolarHBondContact O-N 3.23Å; L80-T82 VanDerWaalsContact O-N 3.14Å; L80-V83 WeakPolarHBondContact O-CB 3.46Å; L80-V83 PolarHBondContact O-N 2.79Å; L80-V83 VanDerWaalsContact O-N 3.08Å; L80-P84 VanDerWaalsContact O-CD 3.3Å; L80-P84 WeakPolarHBondContact O-CD 3.46Å; L80-C290 HydrophobicContact CD2-CB 4.5Å; L80-C290 WeakPolarHBondContact CD2-SG 3.38Å; L80-C290 HydrophobicContact CG-CB 4.2Å
81	L	96.9	Very high	95.6	Very high	80 Å²	80	29.9 Å²	29.9	42%	0.419	16%	0.158	S	C	.	.	H	α-helix	trans	-60.3	-23.6	177.3	-72.6	173	0	0	0	112.8	L77 F78 F79 F85	L77-L81 VanDerWaalsContact O-CG 3.28Å; L77-L81 WeakPolarHBondContact O-CG 3.38Å; L77-L81 PolarHBondContact O-N 3.07Å; F78-L81 HydrophobicContact CD1-CD1 4.47Å; F79-L81 VanDerWaalsContact C-N 3.32Å; F79-L81 PolarHBondContact O-N 3.18Å; L81-F85 WeakPolarHBondContact O-CD2 3.42Å; L81-F85 WeakPolarHBondContact O-CE2 3.23Å
82	T	96.5	Very high	95.2	Very high	0 Å²	0	31.2 Å²	31.2	0%	0	17%	0.171	C	C	.	.	H	α-helix	trans	-84.7	-24.4	177.3	74.6	0	0	0	0	113.3	F79 L80 F85 W86 L104 L107	F79-T82 PolarHBondContact O-N 3.49Å; F79-T82 PolarHBondContact O-OG1 3.45Å; L80-T82 PolarHBondContact O-N 3.23Å; L80-T82 VanDerWaalsContact O-N 3.14Å; T82-F85 WeakPolarHBondContact O-CB 3.13Å; T82-F85 PolarHBondContact O-N 2.65Å; T82-F85 VanDerWaalsContact O-N 3.07Å; T82-W86 PolarHBondContact O-N 3.47Å; T82-W86 PolarHBondContact OG1-NE1 3.07Å; T82-W86 VanDerWaalsContact OG1-NE1 3.16Å; T82-L104 HydrophobicContact CG2-CB 4.4Å; T82-L104 HydrophobicContact CG2-CD2 4.01Å; T82-L104 WeakPolarHBondContact CG2-O 3.13Å; T82-L107 HydrophobicContact CG2-CB 3.6Å
83	V	96	Very high	94.9	Very high	0 Å²	0	33.6 Å²	33.6	0%	0	18%	0.183	C	C	.	.	H	α-helix	trans	-57.9	-42.5	-171.6	175.1	0	0	0	0	113.8	Y37 F41 F79 L80 F85 W86 A87	Y37-V83 HydrophobicContact CG-CG1 4.04Å; Y37-V83 VanDerWaalsContact O-CG1 3.32Å; Y37-V83 WeakPolarHBondContact O-CG1 3.2Å; F41-V83 HydrophobicContact CB-CG1 4.35Å; F79-V83 HydrophobicContact CD1-CG2 4.32Å; F79-V83 HydrophobicContact CE1-CG2 4.44Å; L80-V83 WeakPolarHBondContact O-CB 3.46Å; L80-V83 PolarHBondContact O-N 2.79Å; L80-V83 VanDerWaalsContact O-N 3.08Å; V83-F85 VanDerWaalsContact C-N 3.26Å; V83-F85 PolarHBondContact O-N 3.4Å; V83-W86 PolarHBondContact O-N 3.3Å; V83-A87 WeakPolarHBondContact O-CB 3.41Å; V83-A87 PolarHBondContact O-N 3.39Å
84	P	95.8	Very high	94.8	Very high	53 Å²	53	33.7 Å²	33.7	34%	0.344	18%	0.183	S	C	.	.	H	α-helix	trans	-60.4	-33.8	176.9	-25.6	35.5	0	0	0	113.7	F41 L80 A87 H88	F41-P84 HydrophobicContact CD1-CG 4.33Å; F41-P84 HydrophobicContact CD2-CG 3.67Å; F41-P84 HydrophobicContact CE1-CG 4.45Å; F41-P84 HydrophobicContact CE2-CG 3.82Å; F41-P84 HydrophobicContact CG-CG 3.94Å; F41-P84 HydrophobicContact CZ-CG 4.21Å; L80-P84 VanDerWaalsContact O-CD 3.3Å; L80-P84 WeakPolarHBondContact O-CD 3.46Å; P84-A87 WeakPolarHBondContact O-CB 3.39Å; P84-A87 PolarHBondContact O-N 3.41Å; P84-H88 PolarHBondContact O-N 2.83Å
85	F	96	Very high	94.6	Very high	64 Å²	64	35.5 Å²	35.5	28%	0.281	19%	0.193	S	C	.	.	H	α-helix	trans	-72.7	-40	178.5	-61.9	-92.4	0	0	0	111.2	L81 T82 V83 A87 H88 Y89 F96 V100 L104	L81-F85 WeakPolarHBondContact O-CD2 3.42Å; L81-F85 WeakPolarHBondContact O-CE2 3.23Å; T82-F85 WeakPolarHBondContact O-CB 3.13Å; T82-F85 PolarHBondContact O-N 2.65Å; T82-F85 VanDerWaalsContact O-N 3.07Å; V83-F85 VanDerWaalsContact C-N 3.26Å; V83-F85 PolarHBondContact O-N 3.4Å; F85-A87 VanDerWaalsContact C-N 3.29Å; F85-A87 PolarHBondContact O-N 3.36Å; F85-H88 PolarHBondContact O-N 3.01Å; F85-Y89 WeakPolarHBondContact O-CB 3.38Å; F85-Y89 PolarHBondContact O-N 3.42Å; F85-F96 HydrophobicContact CB-CE2 4.27Å; F85-F96 AromaticContact CD1-CD1 3.92Å; F85-F96 HydrophobicContact CD1-CD1 3.92Å; F85-F96 AromaticContact CD1-CD2 3.89Å; F85-F96 HydrophobicContact CD1-CD2 3.89Å; F85-F96 AromaticContact CD1-CE1 3.74Å; F85-F96 HydrophobicContact CD1-CE1 3.74Å; F85-F96 AromaticContact CD1-CE2 3.72Å; F85-F96 HydrophobicContact CD1-CE2 3.72Å; F85-F96 AromaticContact CD1-CG 4Å; F85-F96 HydrophobicContact CD1-CG 4Å; F85-F96 AromaticContact CD1-CZ 3.64Å; F85-F96 HydrophobicContact CD1-CZ 3.64Å; F85-F96 AromaticContact CE1-CD1 3.99Å; F85-F96 HydrophobicContact CE1-CD1 3.99Å; F85-F96 AromaticContact CE1-CE1 3.9Å; F85-F96 HydrophobicContact CE1-CE1 3.9Å; F85-F96 HydrophobicContact CE1-CG 4.4Å; F85-F96 HydrophobicContact CE1-CZ 4.26Å; F85-F96 HydrophobicContact CG-CE2 4.48Å; F85-V100 HydrophobicContact CE1-CG1 4.49Å; F85-L104 HydrophobicContact CB-CD1 3.5Å; F85-L104 VanDerWaalsContact CB-CD1 3.5Å; F85-L104 HydrophobicContact CD1-CD1 3.56Å; F85-L104 HydrophobicContact CD2-CD1 3.69Å; F85-L104 HydrophobicContact CD2-CD2 3.84Å; F85-L104 HydrophobicContact CD2-CG 4.46Å; F85-L104 HydrophobicContact CE1-CD1 4.16Å; F85-L104 HydrophobicContact CE2-CD1 4.28Å; F85-L104 HydrophobicContact CE2-CD2 4Å; F85-L104 HydrophobicContact CG-CD1 3.29Å; F85-L104 HydrophobicContact CG-CD2 4.33Å; F85-L104 HydrophobicContact CG-CG 4.47Å; F85-L104 HydrophobicContact CZ-CD1 4.49Å
86	W	94.4	Very high	94.3	Very high	36 Å²	36	38.8 Å²	38.8	14%	0.136	21%	0.207	C	C	.	.	H	α-helix	trans	-65.7	-32.9	172.6	-59	124.3	0	0	0	112.2	Y37 T82 V83 Y89 A90 W94 M287	Y37-W86 HydrophobicContact CD2-CB 4.27Å; Y37-W86 HydrophobicContact CE2-CB 4.12Å; T82-W86 PolarHBondContact O-N 3.47Å; T82-W86 PolarHBondContact OG1-NE1 3.07Å; T82-W86 VanDerWaalsContact OG1-NE1 3.16Å; V83-W86 PolarHBondContact O-N 3.3Å; W86-Y89 HydrophobicContact CE3-CD1 4.05Å; W86-Y89 HydrophobicContact CZ3-CD1 4.31Å; W86-Y89 PolarHBondContact O-N 2.67Å; W86-A90 WeakPolarHBondContact O-CB 3.39Å; W86-A90 PolarHBondContact O-N 2.91Å; W86-W94 HydrophobicContact CE3-CZ3 4.17Å; W86-W94 HydrophobicContact CH2-CZ3 4.33Å; W86-W94 HydrophobicContact CZ3-CH2 4.5Å; W86-W94 AromaticContact CZ3-CZ3 3.82Å; W86-W94 HydrophobicContact CZ3-CZ3 3.82Å; W86-M287 HydrophobicContact CG-CE 4.32Å
87	A	94.1	Very high	94.2	Very high	7 Å²	7	40 Å²	40	6%	0.058	22%	0.222	C	C	.	.	H	α-helix	trans	-64	-47.1	173.4	0	0	0	0	0	111.7	Y37 V83 P84 F85 A90 A91	Y37-A87 HydrophobicContact CD2-CB 4.09Å; Y37-A87 HydrophobicContact CG-CB 4.47Å; V83-A87 WeakPolarHBondContact O-CB 3.41Å; V83-A87 PolarHBondContact O-N 3.39Å; P84-A87 WeakPolarHBondContact O-CB 3.39Å; P84-A87 PolarHBondContact O-N 3.41Å; F85-A87 VanDerWaalsContact C-N 3.29Å; F85-A87 PolarHBondContact O-N 3.36Å; A87-A90 PolarHBondContact O-N 3.35Å; A87-A91 PolarHBondContact O-N 3.1Å; A87-A91 VanDerWaalsContact O-N 3.16Å
88	H	94.5	Very high	94	Very high	71 Å²	71	42.1 Å²	42.1	33%	0.329	23%	0.233	S	C	.	.	H	α-helix	trans	-62.5	-45.2	174.2	-177.6	77.8	0	0	0	111.7	P84 F85 A90 A91 A92 D95 F96	P84-H88 PolarHBondContact O-N 2.83Å; F85-H88 PolarHBondContact O-N 3.01Å; H88-A90 VanDerWaalsContact C-N 3.29Å; H88-A90 PolarHBondContact O-N 2.9Å; H88-A91 PolarHBondContact O-N 2.9Å; H88-A91 VanDerWaalsContact O-N 3.09Å; H88-A92 PolarHBondContact O-N 3Å; H88-D95 IonicContact CD2-OD2 3.83Å; H88-D95 IonicContact CE1-OD2 3.77Å; H88-D95 IonicContact NE2-OD2 2.84Å; H88-D95 PolarHBondContact NE2-OD2 3.5Å; H88-F96 HydrophobicContact CB-CE2 4.29Å; H88-F96 HydrophobicContact CB-CZ 4.17Å; H88-F96 AromaticContact CD2-CE2 3.66Å; H88-F96 AromaticContact CD2-CZ 3.67Å; H88-F96 AromaticContact CG-CZ 3.99Å
89	Y	92.9	Very high	93.9	Very high	66 Å²	66	44.2 Å²	44.2	26%	0.259	25%	0.252	S	S	.	.	H	α-helix	trans	-58.9	-40.3	178.4	179	-122.2	0	0	0	112.5	F85 W86 A92 W94 T177	F85-Y89 WeakPolarHBondContact O-CB 3.38Å; F85-Y89 PolarHBondContact O-N 3.42Å; W86-Y89 HydrophobicContact CE3-CD1 4.05Å; W86-Y89 HydrophobicContact CZ3-CD1 4.31Å; W86-Y89 PolarHBondContact O-N 2.67Å; Y89-A92 CarbonylContact O-C 3.48Å; Y89-W94 HydrophobicContact CD2-CB 3.87Å; Y89-W94 AromaticContact CD2-CE3 3.87Å; Y89-W94 HydrophobicContact CD2-CE3 3.87Å; Y89-W94 HydrophobicContact CE2-CB 3.91Å; Y89-W94 AromaticContact CG-CE3 3.98Å; Y89-W94 HydrophobicContact CG-CE3 3.98Å; Y89-T177 WeakPolarHBondContact OH-CB 3.01Å
90	A	89.7	Confident	93.9	Very high	21 Å²	21	46.2 Å²	46.2	17%	0.174	26%	0.264	C	S	.	.	H	α-helix	trans	-66.6	-37.1	175.7	0	0	0	0	0	112.6	A30 L33 W86 A87 H88	A30-A90 WeakPolarHBondContact CA-O 3.33Å; A30-A90 WeakPolarHBondContact CB-O 3.49Å; L33-A90 HydrophobicContact CB-CB 3.86Å; L33-A90 HydrophobicContact CD1-CB 3.92Å; W86-A90 WeakPolarHBondContact O-CB 3.39Å; W86-A90 PolarHBondContact O-N 2.91Å; A87-A90 PolarHBondContact O-N 3.35Å; H88-A90 VanDerWaalsContact C-N 3.29Å; H88-A90 PolarHBondContact O-N 2.9Å
91	A	89.4	Confident	93.8	Very high	57 Å²	57	46.1 Å²	46.1	47%	0.471	26%	0.264	S	S	.	.	H	α-helix	trans	-72.9	-35.9	-179.6	0	0	0	0	0	113.1	P34 A87 H88	P34-A91 HydrophobicContact CB-CB 4.42Å; P34-A91 HydrophobicContact CG-CB 3.68Å; A87-A91 PolarHBondContact O-N 3.1Å; A87-A91 VanDerWaalsContact O-N 3.16Å; H88-A91 PolarHBondContact O-N 2.9Å; H88-A91 VanDerWaalsContact O-N 3.09Å
92	A	89.3	Confident	93.8	Very high	47 Å²	47	45 Å²	45	39%	0.388	26%	0.256	S	S	.	.	S	Bend	trans	-134.8	-105.9	-171.9	0	0	0	0	0	111.6	H88 Y89	H88-A92 PolarHBondContact O-N 3Å; Y89-A92 CarbonylContact O-C 3.48Å
93	Q	89.9	Confident	93.8	Very high	52 Å²	52	50 Å²	50	24%	0.243	28%	0.283	C	S	.	.			trans	-148.8	179.4	-177.4	69.5	-176.9	3.5	0	0	110.1	D95 H175	Q93-D95 WeakPolarHBondContact CG-OD1 3.14Å; Q93-D95 PolarHBondContact NE2-OD1 2.92Å; Q93-D95 PolarHBondContact O-N 2.97Å; Q93-H175 HydrophobicContact CB-CB 4.29Å; Q93-H175 PolarHBondContact OE1-ND1 3.15Å; Q93-H175 VanDerWaalsContact OE1-ND1 3.17Å
94	W	94.1	Very high	93.8	Very high	3 Å²	3	50.4 Å²	50.4	1%	0.011	29%	0.285	C	S	.	.			trans	-84.4	98.8	178.2	-170	-93.8	0	0	0	112.4	W86 Y89 F96 G97 V100 C101 L104 Y176 C178	W86-W94 HydrophobicContact CE3-CZ3 4.17Å; W86-W94 HydrophobicContact CH2-CZ3 4.33Å; W86-W94 HydrophobicContact CZ3-CH2 4.5Å; W86-W94 AromaticContact CZ3-CZ3 3.82Å; W86-W94 HydrophobicContact CZ3-CZ3 3.82Å; Y89-W94 HydrophobicContact CD2-CB 3.87Å; Y89-W94 AromaticContact CD2-CE3 3.87Å; Y89-W94 HydrophobicContact CD2-CE3 3.87Å; Y89-W94 HydrophobicContact CE2-CB 3.91Å; Y89-W94 AromaticContact CG-CE3 3.98Å; Y89-W94 HydrophobicContact CG-CE3 3.98Å; W94-F96 HydrophobicContact CD2-CD2 4.22Å; W94-F96 HydrophobicContact CE3-CD2 4.27Å; W94-F96 HydrophobicContact CH2-CD2 4.16Å; W94-F96 HydrophobicContact CZ2-CB 3.93Å; W94-F96 HydrophobicContact CZ2-CD2 4.02Å; W94-F96 HydrophobicContact CZ2-CG 4.44Å; W94-F96 HydrophobicContact CZ3-CD2 4.26Å; W94-G97 PolarHBondContact NE1-O 3.31Å; W94-V100 HydrophobicContact CZ2-CG1 4.29Å; W94-C101 HydrophobicContact CH2-CB 4.46Å; W94-C101 HydrophobicContact CZ2-CB 3.6Å; W94-L104 HydrophobicContact CH2-CD1 3.72Å; W94-L104 HydrophobicContact CZ2-CD1 4.28Å; W94-Y176 WeakPolarHBondContact CB-O 3.34Å; W94-Y176 PolarHBondContact N-O 3.25Å; W94-Y176 WeakPolarHBondContact O-CB 3.25Å; W94-C178 HydrophobicContact CB-CB 4.41Å; W94-C178 HydrophobicContact CD2-CB 3.44Å; W94-C178 VanDerWaalsContact CD2-CB 3.44Å; W94-C178 HydrophobicContact CE3-CB 3.58Å; W94-C178 HydrophobicContact CG-CB 3.8Å; W94-C178 HydrophobicContact CH2-CB 4.38Å; W94-C178 HydrophobicContact CZ2-CB 4.34Å; W94-C178 HydrophobicContact CZ3-CB 4.04Å
95	D	93.6	Very high	93.8	Very high	87 Å²	87	48.2 Å²	48.2	47%	0.465	27%	0.271	S	S	.	.			trans	-97.8	-2.3	-177.3	-58.9	-51.6	0	0	0	114.2	H88 Q93	H88-D95 IonicContact CD2-OD2 3.83Å; H88-D95 IonicContact CE1-OD2 3.77Å; H88-D95 IonicContact NE2-OD2 2.84Å; H88-D95 PolarHBondContact NE2-OD2 3.5Å; Q93-D95 WeakPolarHBondContact CG-OD1 3.14Å; Q93-D95 PolarHBondContact NE2-OD1 2.92Å; Q93-D95 PolarHBondContact O-N 2.97Å
96	F	93.5	Very high	93.9	Very high	70 Å²	70	45.4 Å²	45.4	31%	0.307	26%	0.259	S	S	.	.	S	Bend	trans	-91.5	-2.2	-170.2	-51.2	-75	0	0	0	114.6	F85 H88 W94 V100	F85-F96 HydrophobicContact CB-CE2 4.27Å; F85-F96 AromaticContact CD1-CD1 3.92Å; F85-F96 HydrophobicContact CD1-CD1 3.92Å; F85-F96 AromaticContact CD1-CD2 3.89Å; F85-F96 HydrophobicContact CD1-CD2 3.89Å; F85-F96 AromaticContact CD1-CE1 3.74Å; F85-F96 HydrophobicContact CD1-CE1 3.74Å; F85-F96 AromaticContact CD1-CE2 3.72Å; F85-F96 HydrophobicContact CD1-CE2 3.72Å; F85-F96 AromaticContact CD1-CG 4Å; F85-F96 HydrophobicContact CD1-CG 4Å; F85-F96 AromaticContact CD1-CZ 3.64Å; F85-F96 HydrophobicContact CD1-CZ 3.64Å; F85-F96 AromaticContact CE1-CD1 3.99Å; F85-F96 HydrophobicContact CE1-CD1 3.99Å; F85-F96 AromaticContact CE1-CE1 3.9Å; F85-F96 HydrophobicContact CE1-CE1 3.9Å; F85-F96 HydrophobicContact CE1-CG 4.4Å; F85-F96 HydrophobicContact CE1-CZ 4.26Å; F85-F96 HydrophobicContact CG-CE2 4.48Å; H88-F96 HydrophobicContact CB-CE2 4.29Å; H88-F96 HydrophobicContact CB-CZ 4.17Å; H88-F96 AromaticContact CD2-CE2 3.66Å; H88-F96 AromaticContact CD2-CZ 3.67Å; H88-F96 AromaticContact CG-CZ 3.99Å; W94-F96 HydrophobicContact CD2-CD2 4.22Å; W94-F96 HydrophobicContact CE3-CD2 4.27Å; W94-F96 HydrophobicContact CH2-CD2 4.16Å; W94-F96 HydrophobicContact CZ2-CB 3.93Å; W94-F96 HydrophobicContact CZ2-CD2 4.02Å; W94-F96 HydrophobicContact CZ2-CG 4.44Å; W94-F96 HydrophobicContact CZ3-CD2 4.26Å; F96-V100 HydrophobicContact CB-CB 3.75Å; F96-V100 HydrophobicContact CB-CG1 3.63Å; F96-V100 HydrophobicContact CB-CG2 4.26Å; F96-V100 HydrophobicContact CG-CG1 4.33Å; F96-V100 WeakPolarHBondContact O-CB 3.41Å; F96-V100 VanDerWaalsContact O-CG2 3.26Å; F96-V100 WeakPolarHBondContact O-CG2 3.05Å
97	G	93.5	Very high	94	Very high	35 Å²	35	45.5 Å²	45.5	36%	0.361	26%	0.262	S	S	.	.	H	α-helix	trans	74.4	176.3	-179	0	0	0	0	0	114.7	W94 C101	W94-G97 PolarHBondContact NE1-O 3.31Å; G97-C101 PolarHBondContact O-N 3.44Å
98	N	94.3	Very high	94.1	Very high	60 Å²	60	45.9 Å²	45.9	32%	0.321	26%	0.262	S	S	.	.	H	α-helix	trans	-69	-40.7	-171	-176.2	74.8	0	0	0	113.7	V100 C101 Q102 R168 S169	N98-V100 VanDerWaalsContact C-N 3.33Å; N98-V100 PolarHBondContact O-N 3.29Å; N98-C101 WeakPolarHBondContact O-CB 3.4Å; N98-C101 PolarHBondContact O-N 3.43Å; N98-Q102 PolarHBondContact ND2-OE1 2.98Å; N98-Q102 PolarHBondContact O-N 2.95Å; N98-R168 VanDerWaalsContact OD1-CA 3.28Å; N98-R168 WeakPolarHBondContact OD1-CA 3.26Å; N98-S169 PolarHBondContact OD1-N 3.43Å
99	T	94.4	Very high	94.2	Very high	113 Å²	113	43.3 Å²	43.3	69%	0.693	25%	0.25	S	S	*	.	H	α-helix	trans	-61.7	-43.1	-178.1	-49.7	0	0	0	0	111.6	Q102 L103	T99-Q102 PolarHBondContact O-N 3.4Å; T99-L103 WeakPolarHBondContact O-CB 3.37Å; T99-L103 PolarHBondContact O-N 3.32Å
100	V	95.8	Very high	94.5	Very high	47 Å²	47	41.3 Å²	41.3	29%	0.285	24%	0.244	S	C	.	.	H	α-helix	trans	-69.8	-36.2	177.9	-179.4	0	0	0	0	110.8	F85 W94 F96 N98 L103 L104	F85-V100 HydrophobicContact CE1-CG1 4.49Å; W94-V100 HydrophobicContact CZ2-CG1 4.29Å; F96-V100 HydrophobicContact CB-CB 3.75Å; F96-V100 HydrophobicContact CB-CG1 3.63Å; F96-V100 HydrophobicContact CB-CG2 4.26Å; F96-V100 HydrophobicContact CG-CG1 4.33Å; F96-V100 WeakPolarHBondContact O-CB 3.41Å; F96-V100 VanDerWaalsContact O-CG2 3.26Å; F96-V100 WeakPolarHBondContact O-CG2 3.05Å; N98-V100 VanDerWaalsContact C-N 3.33Å; N98-V100 PolarHBondContact O-N 3.29Å; V100-L103 PolarHBondContact O-N 3.35Å; V100-L104 HydrophobicContact CG1-CD1 3.49Å; V100-L104 VanDerWaalsContact CG1-CD1 3.49Å; V100-L104 HydrophobicContact CG1-CG 3.92Å; V100-L104 WeakPolarHBondContact O-CB 3.43Å; V100-L104 VanDerWaalsContact O-CG 3.27Å; V100-L104 WeakPolarHBondContact O-CG 3.37Å; V100-L104 PolarHBondContact O-N 3.49Å
101	C	96	Very high	94.8	Very high	0 Å²	0	40.4 Å²	40.4	0%	0	24%	0.237	C	C	.	.	H	α-helix	trans	-57.2	-51.9	174.3	172.4	0	0	0	0	110.8	W94 G97 N98 L103 L104 T105 T167 C178	W94-C101 HydrophobicContact CH2-CB 4.46Å; W94-C101 HydrophobicContact CZ2-CB 3.6Å; G97-C101 PolarHBondContact O-N 3.44Å; N98-C101 WeakPolarHBondContact O-CB 3.4Å; N98-C101 PolarHBondContact O-N 3.43Å; C101-L103 PolarHBondContact O-N 2.95Å; C101-L104 PolarHBondContact O-N 3.23Å; C101-T105 WeakPolarHBondContact O-CB 3.26Å; C101-T105 PolarHBondContact O-N 3.32Å; C101-T105 PolarHBondContact O-OG1 3.09Å; C101-T167 WeakPolarHBondContact SG-CG2 3.38Å; C101-C178 VanDerWaalsContact CA-SG 3.59Å; C101-C178 HydrophobicContact CB-CB 3.93Å; C101-C178 WeakPolarHBondContact CB-SG 3.09Å; C101-C178 VanDerWaalsContact SG-CA 3.58Å; C101-C178 WeakPolarHBondContact SG-CB 3.38Å; C101-C178 CovalentContact SG-SG 2.03Å; C101-C178 PolarHBondContact SG-SG 3.27Å
102	Q	95.8	Very high	95.1	Very high	55 Å²	55	38.2 Å²	38.2	26%	0.257	22%	0.217	S	C	.	.	H	α-helix	trans	-62.4	-42.7	178.4	-69.9	-179.1	-33.8	0	0	113	N98 T99 G106 I164 T167	N98-Q102 PolarHBondContact ND2-OE1 2.98Å; N98-Q102 PolarHBondContact O-N 2.95Å; T99-Q102 PolarHBondContact O-N 3.4Å; Q102-G106 PolarHBondContact O-N 3.14Å; Q102-I164 HydrophobicContact CB-CG2 4.23Å; Q102-T167 WeakPolarHBondContact CG-O 3.47Å; Q102-T167 PolarHBondContact NE2-O 3.35Å
103	L	96.3	Very high	95.5	Very high	107 Å²	107	36 Å²	36	56%	0.56	20%	0.198	S	C	*	.	H	α-helix	trans	-63.5	-48.4	178.5	178.9	63.8	0	0	0	112	T99 V100 C101 G106 L107	T99-L103 WeakPolarHBondContact O-CB 3.37Å; T99-L103 PolarHBondContact O-N 3.32Å; V100-L103 PolarHBondContact O-N 3.35Å; C101-L103 PolarHBondContact O-N 2.95Å; L103-G106 WeakPolarHBondContact O-CA 3.45Å; L103-G106 PolarHBondContact O-N 3.09Å; L103-G106 VanDerWaalsContact O-N 3.16Å; L103-L107 HydrophobicContact CG-CD1 4.46Å; L103-L107 PolarHBondContact O-N 3.42Å
104	L	96.8	Very high	95.9	Very high	8 Å²	8	33.5 Å²	33.5	4%	0.042	19%	0.187	C	C	.	.	H	α-helix	trans	-69.5	-37.8	-178	-68.6	176.1	0	0	0	111.8	T82 F85 W94 V100 C101 G106 L107 Y108	T82-L104 HydrophobicContact CG2-CB 4.4Å; T82-L104 HydrophobicContact CG2-CD2 4.01Å; T82-L104 WeakPolarHBondContact CG2-O 3.13Å; F85-L104 HydrophobicContact CB-CD1 3.5Å; F85-L104 VanDerWaalsContact CB-CD1 3.5Å; F85-L104 HydrophobicContact CD1-CD1 3.56Å; F85-L104 HydrophobicContact CD2-CD1 3.69Å; F85-L104 HydrophobicContact CD2-CD2 3.84Å; F85-L104 HydrophobicContact CD2-CG 4.46Å; F85-L104 HydrophobicContact CE1-CD1 4.16Å; F85-L104 HydrophobicContact CE2-CD1 4.28Å; F85-L104 HydrophobicContact CE2-CD2 4Å; F85-L104 HydrophobicContact CG-CD1 3.29Å; F85-L104 HydrophobicContact CG-CD2 4.33Å; F85-L104 HydrophobicContact CG-CG 4.47Å; F85-L104 HydrophobicContact CZ-CD1 4.49Å; W94-L104 HydrophobicContact CH2-CD1 3.72Å; W94-L104 HydrophobicContact CZ2-CD1 4.28Å; V100-L104 HydrophobicContact CG1-CD1 3.49Å; V100-L104 VanDerWaalsContact CG1-CD1 3.49Å; V100-L104 HydrophobicContact CG1-CG 3.92Å; V100-L104 WeakPolarHBondContact O-CB 3.43Å; V100-L104 VanDerWaalsContact O-CG 3.27Å; V100-L104 WeakPolarHBondContact O-CG 3.37Å; V100-L104 PolarHBondContact O-N 3.49Å; C101-L104 PolarHBondContact O-N 3.23Å; L104-G106 VanDerWaalsContact C-N 3.27Å; L104-G106 PolarHBondContact O-N 3.08Å; L104-L107 HydrophobicContact CD2-CD1 4.44Å; L104-L107 PolarHBondContact O-N 2.78Å; L104-Y108 VanDerWaalsContact O-CB 3.31Å; L104-Y108 WeakPolarHBondContact O-CB 3.45Å; L104-Y108 PolarHBondContact O-N 3.13Å
105	T	95.9	Very high	96.1	Very high	7 Å²	7	33.7 Å²	33.7	4%	0.043	19%	0.189	C	C	.	.	H	α-helix	trans	-60.7	-39.6	169.5	-63.2	0	0	0	0	111.5	C101 Y108 F109 T167	C101-T105 WeakPolarHBondContact O-CB 3.26Å; C101-T105 PolarHBondContact O-N 3.32Å; C101-T105 PolarHBondContact O-OG1 3.09Å; T105-Y108 PolarHBondContact O-N 3.49Å; T105-F109 HydrophobicContact CG2-CD2 3.64Å; T105-F109 HydrophobicContact CG2-CE2 3.54Å; T105-F109 VanDerWaalsContact O-CD2 3.26Å; T105-F109 WeakPolarHBondContact O-CD2 3.37Å; T105-F109 PolarHBondContact O-N 2.62Å; T105-T167 HydrophobicContact CG2-CG2 4.14Å; T105-T167 WeakPolarHBondContact OG1-CG2 3.44Å
106	G	96.8	Very high	96.2	Very high	4 Å²	4	29.5 Å²	29.5	4%	0.041	17%	0.167	C	C	.	.	H	α-helix	trans	-60.4	-51.6	173.4	0	0	0	0	0	112.6	Q102 L103 L104 Y108 F109 I110 I164	Q102-G106 PolarHBondContact O-N 3.14Å; L103-G106 WeakPolarHBondContact O-CA 3.45Å; L103-G106 PolarHBondContact O-N 3.09Å; L103-G106 VanDerWaalsContact O-N 3.16Å; L104-G106 VanDerWaalsContact C-N 3.27Å; L104-G106 PolarHBondContact O-N 3.08Å; G106-Y108 VanDerWaalsContact C-N 3.31Å; G106-Y108 PolarHBondContact O-N 3.15Å; G106-F109 PolarHBondContact O-N 2.84Å; G106-I110 VanDerWaalsContact O-CB 3.27Å; G106-I110 WeakPolarHBondContact O-CB 3.45Å; G106-I110 WeakPolarHBondContact O-CD1 3.28Å; G106-I110 WeakPolarHBondContact O-CG1 3.24Å; G106-I110 PolarHBondContact O-N 3.31Å; G106-I164 VanDerWaalsContact CA-CG1 3.47Å
107	L	97.4	Very high	96.5	Very high	39 Å²	39	27.2 Å²	27.2	20%	0.204	16%	0.157	C	C	.	.	H	α-helix	trans	-61.4	-38.5	177.8	-71.6	175.3	0	0	0	112.6	F78 T82 L103 L104 G111	F78-L107 HydrophobicContact CB-CD2 4.48Å; F78-L107 HydrophobicContact CD1-CD2 4.43Å; F78-L107 HydrophobicContact CG-CD2 4.35Å; T82-L107 HydrophobicContact CG2-CB 3.6Å; L103-L107 HydrophobicContact CG-CD1 4.46Å; L103-L107 PolarHBondContact O-N 3.42Å; L104-L107 HydrophobicContact CD2-CD1 4.44Å; L104-L107 PolarHBondContact O-N 2.78Å; L107-G111 PolarHBondContact O-N 2.96Å
108	Y	96.7	Very high	96.7	Very high	14 Å²	14	25.6 Å²	25.6	6%	0.055	14%	0.14	C	C	.	.	H	α-helix	trans	-59.3	-53.7	174.7	173.4	-86.6	0	0	0	111.1	F79 L104 T105 G106 G111 F112 M287	F79-Y108 HydrophobicContact CD2-CD2 4.05Å; F79-Y108 HydrophobicContact CD2-CE2 4.35Å; F79-Y108 HydrophobicContact CE1-CE2 4.43Å; F79-Y108 AromaticContact CE2-CD2 3.4Å; F79-Y108 HydrophobicContact CE2-CD2 3.4Å; F79-Y108 VanDerWaalsContact CE2-CD2 3.4Å; F79-Y108 AromaticContact CE2-CE2 3.29Å; F79-Y108 HydrophobicContact CE2-CE2 3.29Å; F79-Y108 HydrophobicContact CE2-CG 4.13Å; F79-Y108 AromaticContact CE2-CZ 3.89Å; F79-Y108 AromaticContact CZ-CD2 3.74Å; F79-Y108 HydrophobicContact CZ-CD2 3.74Å; F79-Y108 AromaticContact CZ-CE2 3.35Å; F79-Y108 HydrophobicContact CZ-CE2 3.35Å; L104-Y108 VanDerWaalsContact O-CB 3.31Å; L104-Y108 WeakPolarHBondContact O-CB 3.45Å; L104-Y108 PolarHBondContact O-N 3.13Å; T105-Y108 PolarHBondContact O-N 3.49Å; G106-Y108 VanDerWaalsContact C-N 3.31Å; G106-Y108 PolarHBondContact O-N 3.15Å; Y108-G111 PolarHBondContact O-N 2.69Å; Y108-F112 WeakPolarHBondContact O-CB 3.39Å; Y108-F112 PolarHBondContact O-N 2.74Å; Y108-M287 HydrophobicContact CD2-CE 4.47Å; Y108-M287 HydrophobicContact CE2-CE 3.76Å
109	F	96.7	Very high	96.7	Very high	17 Å²	17	22.8 Å²	22.8	8%	0.075	13%	0.125	C	C	.	.	H	α-helix	trans	-70.1	-37.6	-178.7	-78.4	-59.8	0	0	0	112.7	T105 G106 F112 F113 S160 H194 I198	T105-F109 HydrophobicContact CG2-CD2 3.64Å; T105-F109 HydrophobicContact CG2-CE2 3.54Å; T105-F109 VanDerWaalsContact O-CD2 3.26Å; T105-F109 WeakPolarHBondContact O-CD2 3.37Å; T105-F109 PolarHBondContact O-N 2.62Å; G106-F109 PolarHBondContact O-N 2.84Å; F109-F112 PolarHBondContact O-N 2.79Å; F109-F113 HydrophobicContact CB-CD2 4.22Å; F109-F113 HydrophobicContact CB-CE2 4.13Å; F109-F113 AromaticContact CD1-CE2 3.91Å; F109-F113 HydrophobicContact CD1-CE2 3.91Å; F109-F113 HydrophobicContact CG-CE2 4.36Å; F109-F113 WeakPolarHBondContact O-CD2 3.14Å; F109-F113 PolarHBondContact O-N 3.02Å; F109-S160 WeakPolarHBondContact CB-OG 3.26Å; F109-S160 PolarHBondContact O-OG 2.94Å; F109-H194 AromaticContact CZ-CE1 3.68Å; F109-I198 HydrophobicContact CE1-CD1 3.98Å
110	I	97.8	Very high	96.8	Very high	24 Å²	24	18.1 Å²	18.1	12%	0.123	10%	0.095	C	C	.	.	H	α-helix	trans	-58.9	-54	174.8	-73.3	166.9	0	0	0	108.3	F78 G106 F112 F113 S114 W153 V157 S160	F78-I110 HydrophobicContact CD2-CG2 4.06Å; G106-I110 VanDerWaalsContact O-CB 3.27Å; G106-I110 WeakPolarHBondContact O-CB 3.45Å; G106-I110 WeakPolarHBondContact O-CD1 3.28Å; G106-I110 WeakPolarHBondContact O-CG1 3.24Å; G106-I110 PolarHBondContact O-N 3.31Å; I110-F112 VanDerWaalsContact C-N 3.29Å; I110-F112 PolarHBondContact O-N 3.3Å; I110-F113 PolarHBondContact O-N 3.31Å; I110-S114 WeakPolarHBondContact O-CB 3.25Å; I110-S114 PolarHBondContact O-N 3.22Å; I110-S114 PolarHBondContact O-OG 3.47Å; I110-W153 HydrophobicContact CG2-CE3 4.09Å; I110-W153 HydrophobicContact CG2-CZ3 3.61Å; I110-V157 HydrophobicContact CD1-CG2 3.98Å; I110-V157 HydrophobicContact CG1-CG2 4.22Å; I110-S160 WeakPolarHBondContact CA-OG 3.34Å; I110-S160 WeakPolarHBondContact CG1-OG 3.28Å; I110-S160 PolarHBondContact N-OG 2.71Å; I110-S160 VanDerWaalsContact N-OG 3.13Å
111	G	97.3	Very high	96.8	Very high	3 Å²	3	17.3 Å²	17.3	3%	0.031	9%	0.09	C	C	.	.	H	α-helix	trans	-59.3	-36.8	178.2	0	0	0	0	0	113.5	S75 L107 Y108 G115	S75-G111 WeakPolarHBondContact O-CA 3.43Å; S75-G111 PolarHBondContact OG-O 3.44Å; L107-G111 PolarHBondContact O-N 2.96Å; Y108-G111 PolarHBondContact O-N 2.69Å; G111-G115 PolarHBondContact O-N 3.37Å; G111-G115 VanDerWaalsContact O-N 3.13Å
112	F	96.3	Very high	96.7	Very high	11 Å²	11	17.4 Å²	17.4	5%	0.048	9%	0.09	C	C	.	.	H	α-helix	trans	-65.4	-54.3	174.6	174.1	-101.7	0	0	0	112.4	F79 Y108 F109 I110 G115 I116 I198 W248	F79-F112 HydrophobicContact CE2-CB 4.5Å; Y108-F112 WeakPolarHBondContact O-CB 3.39Å; Y108-F112 PolarHBondContact O-N 2.74Å; F109-F112 PolarHBondContact O-N 2.79Å; I110-F112 VanDerWaalsContact C-N 3.29Å; I110-F112 PolarHBondContact O-N 3.3Å; F112-G115 PolarHBondContact O-N 2.92Å; F112-I116 PolarHBondContact O-N 3.42Å; F112-I198 HydrophobicContact CE1-CG2 4.26Å; F112-I198 HydrophobicContact CZ-CG2 4.31Å; F112-W248 HydrophobicContact CD2-CD2 4.2Å; F112-W248 HydrophobicContact CD2-CE3 4.05Å; F112-W248 AromaticContact CD2-CH2 3.56Å; F112-W248 HydrophobicContact CD2-CH2 3.56Å; F112-W248 AromaticContact CD2-CZ2 3.74Å; F112-W248 HydrophobicContact CD2-CZ2 3.74Å; F112-W248 AromaticContact CD2-CZ3 3.73Å; F112-W248 HydrophobicContact CD2-CZ3 3.73Å; F112-W248 AromaticContact CE2-CD2 3.69Å; F112-W248 HydrophobicContact CE2-CD2 3.69Å; F112-W248 AromaticContact CE2-CE3 3.45Å; F112-W248 HydrophobicContact CE2-CE3 3.45Å; F112-W248 VanDerWaalsContact CE2-CE3 3.45Å; F112-W248 HydrophobicContact CE2-CG 4.42Å; F112-W248 AromaticContact CE2-CH2 3.87Å; F112-W248 HydrophobicContact CE2-CH2 3.87Å; F112-W248 HydrophobicContact CE2-CZ2 4.11Å; F112-W248 AromaticContact CE2-CZ3 3.54Å; F112-W248 HydrophobicContact CE2-CZ3 3.54Å; F112-W248 HydrophobicContact CZ-CE3 4.44Å
113	F	97.7	Very high	96.6	Very high	0 Å²	0	14.8 Å²	14.8	0%	0	8%	0.078	C	C	.	.	H	α-helix	trans	-69.9	-45.3	-176.5	-73	-58.8	0	0	0	112.4	F109 I110 G115 I116 F117 A156 A159 K197 I198 L201	F109-F113 HydrophobicContact CB-CD2 4.22Å; F109-F113 HydrophobicContact CB-CE2 4.13Å; F109-F113 AromaticContact CD1-CE2 3.91Å; F109-F113 HydrophobicContact CD1-CE2 3.91Å; F109-F113 HydrophobicContact CG-CE2 4.36Å; F109-F113 WeakPolarHBondContact O-CD2 3.14Å; F109-F113 PolarHBondContact O-N 3.02Å; I110-F113 PolarHBondContact O-N 3.31Å; F113-G115 PolarHBondContact O-N 3.29Å; F113-I116 VanDerWaalsContact O-CG2 3.26Å; F113-I116 WeakPolarHBondContact O-CG2 3.35Å; F113-I116 PolarHBondContact O-N 2.9Å; F113-F117 HydrophobicContact CB-CD2 4.42Å; F113-F117 HydrophobicContact CB-CE2 3.98Å; F113-F117 HydrophobicContact CB-CZ 4.41Å; F113-F117 HydrophobicContact CD1-CZ 4.4Å; F113-F117 WeakPolarHBondContact O-CB 3.34Å; F113-F117 WeakPolarHBondContact O-CD2 3.5Å; F113-F117 WeakPolarHBondContact O-CG 3.3Å; F113-F117 PolarHBondContact O-N 3.41Å; F113-A156 HydrophobicContact CB-CB 4.15Å; F113-A159 HydrophobicContact CD1-CB 4.39Å; F113-A159 HydrophobicContact CD2-CB 3.8Å; F113-A159 HydrophobicContact CE2-CB 4.12Å; F113-A159 HydrophobicContact CG-CB 3.99Å; F113-K197 HydrophobicContact CZ-CD 4.38Å; F113-I198 HydrophobicContact CZ-CG1 4.21Å; F113-L201 HydrophobicContact CD1-CB 4.26Å; F113-L201 HydrophobicContact CD1-CD1 4.3Å; F113-L201 HydrophobicContact CE1-CB 4.02Å; F113-L201 HydrophobicContact CE1-CD1 4.01Å
114	S	98.2	Very high	96.5	Very high	0 Å²	0	12.5 Å²	12.5	0%	0	7%	0.066	C	C	.	.	H	α-helix	trans	-62.9	-34	176.3	53.4	0	0	0	0	111.3	S75 I110 F117 F118 W153	S75-S114 WeakPolarHBondContact CB-OG 3.3Å; S75-S114 PolarHBondContact OG-OG 3.4Å; I110-S114 WeakPolarHBondContact O-CB 3.25Å; I110-S114 PolarHBondContact O-N 3.22Å; I110-S114 PolarHBondContact O-OG 3.47Å; S114-F117 PolarHBondContact O-N 3.48Å; S114-F118 WeakPolarHBondContact O-CB 3.38Å; S114-F118 WeakPolarHBondContact O-CD2 3.46Å; S114-F118 PolarHBondContact O-N 3.37Å; S114-W153 WeakPolarHBondContact OG-CZ3 3.26Å
115	G	97.1	Very high	96.2	Very high	6 Å²	6	12.3 Å²	12.3	6%	0.062	6%	0.064	C	C	.	.	H	α-helix	trans	-58.8	-53.6	178.2	0	0	0	0	0	111.6	L72 S75 G111 F112 F113 F118 I119	L72-G115 WeakPolarHBondContact CD1-O 3.5Å; S75-G115 WeakPolarHBondContact OG-CA 3.05Å; S75-G115 PolarHBondContact OG-N 2.83Å; G111-G115 PolarHBondContact O-N 3.37Å; G111-G115 VanDerWaalsContact O-N 3.13Å; F112-G115 PolarHBondContact O-N 2.92Å; F113-G115 PolarHBondContact O-N 3.29Å; G115-F118 PolarHBondContact O-N 3.13Å; G115-I119 WeakPolarHBondContact O-CG1 3.43Å; G115-I119 PolarHBondContact O-N 3.09Å; G115-I119 VanDerWaalsContact O-N 3.11Å
116	I	97	Very high	95.9	Very high	0 Å²	0	13.7 Å²	13.7	0%	0	7%	0.069	C	C	.	.	H	α-helix	trans	-67.8	-37.2	178.8	-171	50.6	0	0	0	112.7	F112 F113 F118 I119 I120 P206 Y244	F112-I116 PolarHBondContact O-N 3.42Å; F113-I116 VanDerWaalsContact O-CG2 3.26Å; F113-I116 WeakPolarHBondContact O-CG2 3.35Å; F113-I116 PolarHBondContact O-N 2.9Å; I116-F118 PolarHBondContact O-N 3.45Å; I116-I119 HydrophobicContact CD1-CB 4.34Å; I116-I119 HydrophobicContact CD1-CG2 4.43Å; I116-I119 PolarHBondContact O-N 3.42Å; I116-I120 HydrophobicContact CG1-CD1 4.21Å; I116-I120 WeakPolarHBondContact O-CG1 3.28Å; I116-I120 PolarHBondContact O-N 3.36Å; I116-P206 HydrophobicContact CD1-CB 3.55Å; I116-P206 HydrophobicContact CD1-CG 3.81Å; I116-P206 HydrophobicContact CG1-CB 3.97Å; I116-P206 HydrophobicContact CG1-CG 3.83Å; I116-Y244 HydrophobicContact CB-CE2 4.1Å; I116-Y244 HydrophobicContact CD1-CD1 3.67Å; I116-Y244 HydrophobicContact CD1-CD2 4.22Å; I116-Y244 HydrophobicContact CD1-CE1 3.31Å; I116-Y244 HydrophobicContact CD1-CE2 3.91Å; I116-Y244 HydrophobicContact CD1-CG 4.12Å; I116-Y244 VanDerWaalsContact CD1-CZ 3.45Å; I116-Y244 HydrophobicContact CG1-CE1 3.95Å; I116-Y244 HydrophobicContact CG1-CE2 4.33Å
117	F	98.2	Very high	95.6	Very high	22 Å²	22	15.9 Å²	15.9	10%	0.096	8%	0.076	C	C	.	.	H	α-helix	trans	-64.6	-39.8	176.9	-64.1	-24.5	0	0	0	112.4	F113 S114 I120 L121 T152 V155 A156 L201 L205	F113-F117 HydrophobicContact CB-CD2 4.42Å; F113-F117 HydrophobicContact CB-CE2 3.98Å; F113-F117 HydrophobicContact CB-CZ 4.41Å; F113-F117 HydrophobicContact CD1-CZ 4.4Å; F113-F117 WeakPolarHBondContact O-CB 3.34Å; F113-F117 WeakPolarHBondContact O-CD2 3.5Å; F113-F117 WeakPolarHBondContact O-CG 3.3Å; F113-F117 PolarHBondContact O-N 3.41Å; S114-F117 PolarHBondContact O-N 3.48Å; F117-I120 HydrophobicContact CD1-CD1 4.34Å; F117-I120 WeakPolarHBondContact O-CB 3.36Å; F117-I120 PolarHBondContact O-N 2.9Å; F117-L121 WeakPolarHBondContact O-CG 3.3Å; F117-L121 PolarHBondContact O-N 3.38Å; F117-T152 HydrophobicContact CB-CG2 3.51Å; F117-T152 HydrophobicContact CD2-CG2 4.15Å; F117-T152 HydrophobicContact CG-CG2 4.32Å; F117-V155 HydrophobicContact CD2-CG1 4.49Å; F117-V155 HydrophobicContact CE2-CG1 3.82Å; F117-V155 HydrophobicContact CZ-CG1 4.33Å; F117-A156 HydrophobicContact CD2-CB 4.36Å; F117-A156 HydrophobicContact CE2-CB 4.47Å; F117-L201 HydrophobicContact CE1-CB 4.38Å; F117-L201 HydrophobicContact CE1-CD2 4.45Å; F117-L201 HydrophobicContact CZ-CD1 4.32Å; F117-L201 HydrophobicContact CZ-CD2 4.46Å; F117-L205 HydrophobicContact CE1-CD2 4.34Å
118	F	97.5	Very high	95.2	Very high	0 Å²	0	16 Å²	16	0%	0	8%	0.077	C	C	.	.	H	α-helix	trans	-68.6	-33.3	174.4	-75.8	-60.5	0	0	0	112.5	Y68 N71 L72 S114 G115 I116 L121 L122 S149 T152 W153	Y68-F118 HydrophobicContact CD1-CD1 4.08Å; Y68-F118 HydrophobicContact CD1-CE1 4.23Å; N71-F118 HydrophobicContact CB-CD1 3.82Å; N71-F118 HydrophobicContact CB-CD2 3.77Å; N71-F118 HydrophobicContact CB-CE1 3.49Å; N71-F118 VanDerWaalsContact CB-CE1 3.49Å; N71-F118 HydrophobicContact CB-CE2 3.46Å; N71-F118 VanDerWaalsContact CB-CE2 3.46Å; N71-F118 HydrophobicContact CB-CG 3.99Å; N71-F118 HydrophobicContact CB-CZ 3.32Å; L72-F118 HydrophobicContact CB-CB 4.15Å; L72-F118 HydrophobicContact CD1-CB 4.35Å; S114-F118 WeakPolarHBondContact O-CB 3.38Å; S114-F118 WeakPolarHBondContact O-CD2 3.46Å; S114-F118 PolarHBondContact O-N 3.37Å; G115-F118 PolarHBondContact O-N 3.13Å; I116-F118 PolarHBondContact O-N 3.45Å; F118-L121 HydrophobicContact CD1-CD1 4.02Å; F118-L121 HydrophobicContact CE1-CD1 4.16Å; F118-L121 PolarHBondContact O-N 2.85Å; F118-L122 WeakPolarHBondContact O-CB 3.37Å; F118-L122 VanDerWaalsContact O-CG 3.25Å; F118-L122 WeakPolarHBondContact O-CG 3.44Å; F118-L122 PolarHBondContact O-N 3.48Å; F118-S149 WeakPolarHBondContact CE1-OG 3.28Å; F118-T152 HydrophobicContact CD2-CG2 4.42Å; F118-T152 HydrophobicContact CE1-CG2 4.1Å; F118-T152 HydrophobicContact CE2-CG2 3.97Å; F118-T152 HydrophobicContact CZ-CG2 3.78Å; F118-W153 AromaticContact CE2-CE2 3.94Å; F118-W153 HydrophobicContact CE2-CZ2 4.17Å; F118-W153 AromaticContact CE2-NE1 3.91Å; F118-W153 AromaticContact CZ-NE1 3.77Å
119	I	95.5	Very high	94.7	Very high	2 Å²	2	16.5 Å²	16.5	1%	0.01	8%	0.084	C	C	.	.	H	α-helix	trans	-64.2	-40.9	171.3	-68.9	171	0	0	0	111.3	L72 G115 I116 L122 T123 I240 M241 Y244	L72-I119 HydrophobicContact CD1-CD1 4.39Å; L72-I119 HydrophobicContact CD1-CG1 4.01Å; L72-I119 HydrophobicContact CD2-CG1 4.04Å; G115-I119 WeakPolarHBondContact O-CG1 3.43Å; G115-I119 PolarHBondContact O-N 3.09Å; G115-I119 VanDerWaalsContact O-N 3.11Å; I116-I119 HydrophobicContact CD1-CB 4.34Å; I116-I119 HydrophobicContact CD1-CG2 4.43Å; I116-I119 PolarHBondContact O-N 3.42Å; I119-L122 PolarHBondContact O-N 3.19Å; I119-T123 PolarHBondContact O-N 3.04Å; I119-T123 PolarHBondContact O-OG1 3Å; I119-I240 HydrophobicContact CD1-CG2 4.06Å; I119-I240 HydrophobicContact CG1-CG2 4.01Å; I119-I240 HydrophobicContact CG2-CG2 4.46Å; I119-M241 HydrophobicContact CG2-CE 3.47Å; I119-M241 VanDerWaalsContact CG2-CE 3.47Å; I119-M241 HydrophobicContact CG2-SD 3.7Å; I119-Y244 HydrophobicContact CD1-CD2 3.96Å; I119-Y244 HydrophobicContact CD1-CG 4.26Å
120	I	96.6	Very high	94.2	Very high	14 Å²	14	16.4 Å²	16.4	7%	0.072	9%	0.085	C	C	.	.	H	α-helix	trans	-61.7	-49	173.3	-73.9	164.5	0	0	0	110.4	I116 F117 L122 T123 I124 L205 P206 V209	I116-I120 HydrophobicContact CG1-CD1 4.21Å; I116-I120 WeakPolarHBondContact O-CG1 3.28Å; I116-I120 PolarHBondContact O-N 3.36Å; F117-I120 HydrophobicContact CD1-CD1 4.34Å; F117-I120 WeakPolarHBondContact O-CB 3.36Å; F117-I120 PolarHBondContact O-N 2.9Å; I120-L122 VanDerWaalsContact C-N 3.31Å; I120-L122 PolarHBondContact O-N 3.43Å; I120-T123 WeakPolarHBondContact O-CA 3.39Å; I120-T123 WeakPolarHBondContact O-CB 3.4Å; I120-T123 PolarHBondContact O-N 3.28Å; I120-T123 VanDerWaalsContact O-N 3.07Å; I120-I124 HydrophobicContact CG2-CD1 3.77Å; I120-I124 HydrophobicContact CG2-CG1 4.47Å; I120-I124 WeakPolarHBondContact O-CG1 3.42Å; I120-I124 PolarHBondContact O-N 3.39Å; I120-L205 HydrophobicContact CD1-CD2 3.98Å; I120-L205 HydrophobicContact CD1-CG 3.98Å; I120-P206 HydrophobicContact CD1-CB 4Å; I120-P206 HydrophobicContact CG1-CB 3.98Å; I120-V209 HydrophobicContact CG2-CG1 4.22Å; I120-V209 HydrophobicContact CG2-CG2 4.05Å
121	L	96.3	Very high	93.6	Very high	31 Å²	31	17 Å²	17	16%	0.162	9%	0.09	C	C	.	.	H	α-helix	trans	-62.2	-37.5	178.5	-73.6	178.1	0	0	0	112.5	Y68 F117 F118 T123 I124 D125 T152	Y68-L121 HydrophobicContact CD1-CD1 4.42Å; Y68-L121 HydrophobicContact CD2-CB 4.02Å; Y68-L121 HydrophobicContact CE1-CB 4.35Å; Y68-L121 HydrophobicContact CE1-CD1 3.91Å; Y68-L121 HydrophobicContact CE2-CB 3.75Å; Y68-L121 HydrophobicContact CG-CB 4.41Å; F117-L121 WeakPolarHBondContact O-CG 3.3Å; F117-L121 PolarHBondContact O-N 3.38Å; F118-L121 HydrophobicContact CD1-CD1 4.02Å; F118-L121 HydrophobicContact CE1-CD1 4.16Å; F118-L121 PolarHBondContact O-N 2.85Å; L121-T123 VanDerWaalsContact C-N 3.34Å; L121-I124 PolarHBondContact O-N 3.13Å; L121-D125 VanDerWaalsContact O-CB 3.22Å; L121-D125 WeakPolarHBondContact O-CB 3.19Å; L121-D125 PolarHBondContact O-N 3.42Å; L121-T152 HydrophobicContact CD1-CG2 4.41Å; L121-T152 VanDerWaalsContact CD1-OG1 3.32Å; L121-T152 WeakPolarHBondContact CD1-OG1 3.27Å
122	L	93.4	Very high	93.1	Very high	1 Å²	1	21 Å²	21	1%	0.005	11%	0.107	C	C	.	.	H	α-helix	trans	-61.6	-43	172	-78	167.4	0	0	0	111.4	T65 Y68 L69 L72 F118 I119 I120 D125 R126 I237	T65-L122 HydrophobicContact CG2-CD2 3.75Å; Y68-L122 HydrophobicContact CD2-CD2 4.31Å; L69-L122 HydrophobicContact CD2-CD1 3.9Å; L69-L122 HydrophobicContact CD2-CD2 4.23Å; L69-L122 HydrophobicContact CG-CD2 4.14Å; L72-L122 HydrophobicContact CD2-CD1 3.93Å; F118-L122 WeakPolarHBondContact O-CB 3.37Å; F118-L122 VanDerWaalsContact O-CG 3.25Å; F118-L122 WeakPolarHBondContact O-CG 3.44Å; F118-L122 PolarHBondContact O-N 3.48Å; I119-L122 PolarHBondContact O-N 3.19Å; I120-L122 VanDerWaalsContact C-N 3.31Å; I120-L122 PolarHBondContact O-N 3.43Å; L122-D125 PolarHBondContact O-N 2.88Å; L122-R126 WeakPolarHBondContact O-CG 3.4Å; L122-R126 PolarHBondContact O-N 3.11Å; L122-I237 HydrophobicContact CB-CD1 4.35Å; L122-I237 HydrophobicContact CB-CG2 4.35Å; L122-I237 HydrophobicContact CD2-CD1 4.42Å
123	T	93	Very high	92.3	Very high	0 Å²	0	23.2 Å²	23.2	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-62.3	-46.3	176.8	-57.8	0	0	0	0	111.7	I119 I120 L121 R126 Y127 V209 C213 Y214 M241	I119-T123 PolarHBondContact O-N 3.04Å; I119-T123 PolarHBondContact O-OG1 3Å; I120-T123 WeakPolarHBondContact O-CA 3.39Å; I120-T123 WeakPolarHBondContact O-CB 3.4Å; I120-T123 PolarHBondContact O-N 3.28Å; I120-T123 VanDerWaalsContact O-N 3.07Å; L121-T123 VanDerWaalsContact C-N 3.34Å; T123-R126 PolarHBondContact O-N 2.88Å; T123-Y127 WeakPolarHBondContact O-CB 3.46Å; T123-Y127 PolarHBondContact O-N 3.33Å; T123-V209 HydrophobicContact CG2-CG1 3.98Å; T123-C213 HydrophobicContact CG2-CB 3.74Å; T123-Y214 HydrophobicContact CG2-CD2 4.47Å; T123-Y214 HydrophobicContact CG2-CE2 3.85Å; T123-M241 HydrophobicContact CG2-CE 4.39Å; T123-M241 WeakPolarHBondContact OG1-CE 3.34Å
124	I	93.6	Very high	91.4	Very high	60 Å²	60	29.2 Å²	29.2	31%	0.308	16%	0.164	S	C	.	.	H	α-helix	trans	-65.1	-44.3	177.7	-65.1	168.8	0	0	0	110.8	I120 L121 R126 Y127 L128 V209	I120-I124 HydrophobicContact CG2-CD1 3.77Å; I120-I124 HydrophobicContact CG2-CG1 4.47Å; I120-I124 WeakPolarHBondContact O-CG1 3.42Å; I120-I124 PolarHBondContact O-N 3.39Å; L121-I124 PolarHBondContact O-N 3.13Å; I124-R126 VanDerWaalsContact C-N 3.28Å; I124-R126 PolarHBondContact O-N 2.95Å; I124-Y127 WeakPolarHBondContact O-CB 3.35Å; I124-Y127 PolarHBondContact O-N 2.87Å; I124-Y127 VanDerWaalsContact O-N 3.14Å; I124-L128 HydrophobicContact CG2-CD1 4.06Å; I124-L128 HydrophobicContact CG2-CG 4.3Å; I124-L128 WeakPolarHBondContact O-CG 3.35Å; I124-L128 PolarHBondContact O-N 2.81Å; I124-V209 HydrophobicContact CG1-CG1 4.13Å
125	D	91.4	Very high	90.5	Very high	3 Å²	3	35.4 Å²	35.4	2%	0.016	19%	0.191	C	C	.	.	H	α-helix	trans	-58.2	-40.3	176	165.8	74.2	0	0	0	111.8	T65 Y68 L121 L122 A129 R140	T65-D125 PolarHBondContact OG1-OD2 3.47Å; Y68-D125 HydrophobicContact CD2-CB 4.28Å; Y68-D125 HydrophobicContact CE2-CB 4.03Å; L121-D125 VanDerWaalsContact O-CB 3.22Å; L121-D125 WeakPolarHBondContact O-CB 3.19Å; L121-D125 PolarHBondContact O-N 3.42Å; L122-D125 PolarHBondContact O-N 2.88Å; D125-A129 WeakPolarHBondContact O-CB 3.46Å; D125-A129 PolarHBondContact O-N 2.99Å; D125-A129 VanDerWaalsContact O-N 3.17Å; D125-R140 PolarHBondContact O-NE 3.47Å; D125-R140 IonicContact OD1-CZ 3.16Å; D125-R140 IonicContact OD1-NE 2.71Å; D125-R140 PolarHBondContact OD1-NE 3.45Å; D125-R140 IonicContact OD1-NH2 2.78Å; D125-R140 PolarHBondContact OD1-NH2 3.41Å; D125-R140 IonicContact OD2-NH2 3.57Å
126	R	89.6	Confident	89.5	Confident	37 Å²	37	35.4 Å²	35.4	14%	0.14	19%	0.19	C	C	.	.	H	α-helix	trans	-69.2	-42.5	173.7	-69.7	-53.2	83.2	-160.4	4.6	112.7	T65 L122 T123 I124 A129 V130 I237	T65-R126 PolarHBondContact OG1-NH2 3.44Å; L122-R126 WeakPolarHBondContact O-CG 3.4Å; L122-R126 PolarHBondContact O-N 3.11Å; T123-R126 PolarHBondContact O-N 2.88Å; I124-R126 VanDerWaalsContact C-N 3.28Å; I124-R126 PolarHBondContact O-N 2.95Å; R126-A129 PolarHBondContact O-N 2.9Å; R126-V130 WeakPolarHBondContact O-CG2 3.31Å; R126-V130 PolarHBondContact O-N 3.07Å; R126-V130 VanDerWaalsContact O-N 3.09Å; R126-I237 HydrophobicContact CG-CB 4.06Å; R126-I237 HydrophobicContact CG-CG1 3.48Å; R126-I237 VanDerWaalsContact CG-CG1 3.48Å; R126-I237 HydrophobicContact CG-CG2 4.31Å
127	Y	90.2	Very high	88.6	Confident	49 Å²	49	42.6 Å²	42.6	19%	0.192	23%	0.228	C	C	.	.	H	α-helix	trans	-57.1	-51.8	177.4	173.4	-99.7	0	0	0	111.2	T123 I124 A129 V130 V131 H132 C213 I217	T123-Y127 WeakPolarHBondContact O-CB 3.46Å; T123-Y127 PolarHBondContact O-N 3.33Å; I124-Y127 WeakPolarHBondContact O-CB 3.35Å; I124-Y127 PolarHBondContact O-N 2.87Å; I124-Y127 VanDerWaalsContact O-N 3.14Å; Y127-A129 VanDerWaalsContact C-N 3.32Å; Y127-A129 PolarHBondContact O-N 2.78Å; Y127-V130 PolarHBondContact O-N 2.98Å; Y127-V130 VanDerWaalsContact O-N 3.13Å; Y127-V131 HydrophobicContact CD2-CB 4.34Å; Y127-V131 HydrophobicContact CD2-CG2 3.71Å; Y127-V131 HydrophobicContact CE2-CB 4.05Å; Y127-V131 HydrophobicContact CE2-CG1 4.25Å; Y127-V131 HydrophobicContact CE2-CG2 3.59Å; Y127-V131 HydrophobicContact CG-CG2 4.46Å; Y127-V131 WeakPolarHBondContact O-CB 2.97Å; Y127-V131 PolarHBondContact O-N 2.76Å; Y127-H132 AromaticContact CE1-CD2 3.71Å; Y127-H132 AromaticContact CE1-NE2 3.84Å; Y127-C213 VanDerWaalsContact CD2-CA 3.46Å; Y127-C213 HydrophobicContact CD2-CB 3.84Å; Y127-C213 VanDerWaalsContact CD2-O 3.29Å; Y127-C213 WeakPolarHBondContact CD2-O 3.43Å; Y127-C213 HydrophobicContact CG-CB 4.07Å; Y127-I217 HydrophobicContact CD2-CG1 4.12Å
128	L	89.6	Confident	87.6	Confident	41 Å²	41	49.9 Å²	49.9	22%	0.215	26%	0.26	C	S	.	.	H	α-helix	trans	-59.7	-42.9	178.4	-67.9	175.8	0	0	0	111.5	I124 V130 H132 F135 A136	I124-L128 HydrophobicContact CG2-CD1 4.06Å; I124-L128 HydrophobicContact CG2-CG 4.3Å; I124-L128 WeakPolarHBondContact O-CG 3.35Å; I124-L128 PolarHBondContact O-N 2.81Å; L128-V130 VanDerWaalsContact C-N 3.26Å; L128-V130 PolarHBondContact O-N 2.93Å; L128-H132 HydrophobicContact CD2-CB 4.43Å; L128-H132 CarbonylContact O-C 3.57Å; L128-H132 WeakPolarHBondContact O-CA 3.36Å; L128-H132 PolarHBondContact O-N 3.48Å; L128-F135 HydrophobicContact CD2-CD1 4.33Å; L128-F135 HydrophobicContact CD2-CE1 4.46Å; L128-A136 WeakPolarHBondContact O-CB 3.45Å
129	A	86.8	Confident	86.7	Confident	25 Å²	25	51 Å²	51	21%	0.207	27%	0.27	C	S	.	.	H	α-helix	trans	-62.8	-29.6	178.6	0	0	0	0	0	113.9	D125 R126 Y127	D125-A129 WeakPolarHBondContact O-CB 3.46Å; D125-A129 PolarHBondContact O-N 2.99Å; D125-A129 VanDerWaalsContact O-N 3.17Å; R126-A129 PolarHBondContact O-N 2.9Å; Y127-A129 VanDerWaalsContact C-N 3.32Å; Y127-A129 PolarHBondContact O-N 2.78Å
130	V	84.6	Confident	86.3	Confident	15 Å²	15	54 Å²	54	9%	0.091	28%	0.281	C	S	.	.	H	α-helix	trans	-94.8	-46.8	-176.3	173	0	0	0	0	112.2	R126 Y127 L128 I217 T220 R230 V234	R126-V130 WeakPolarHBondContact O-CG2 3.31Å; R126-V130 PolarHBondContact O-N 3.07Å; R126-V130 VanDerWaalsContact O-N 3.09Å; Y127-V130 PolarHBondContact O-N 2.98Å; Y127-V130 VanDerWaalsContact O-N 3.13Å; L128-V130 VanDerWaalsContact C-N 3.26Å; L128-V130 PolarHBondContact O-N 2.93Å; V130-I217 HydrophobicContact CB-CG1 4.35Å; V130-I217 HydrophobicContact CG1-CG1 4.38Å; V130-I217 HydrophobicContact CG1-CG2 4.29Å; V130-T220 HydrophobicContact CG1-CG2 4.21Å; V130-R230 HydrophobicContact CG2-CG 3.84Å; V130-V234 HydrophobicContact CG2-CG2 4.03Å
131	V	86.8	Confident	85.9	Confident	38 Å²	38	56 Å²	56	23%	0.23	29%	0.293	C	S	.	.	H	α-helix	trans	-90.3	-35.8	-171.5	-176.7	0	0	0	0	111.6	Y127 I217	Y127-V131 HydrophobicContact CD2-CB 4.34Å; Y127-V131 HydrophobicContact CD2-CG2 3.71Å; Y127-V131 HydrophobicContact CE2-CB 4.05Å; Y127-V131 HydrophobicContact CE2-CG1 4.25Å; Y127-V131 HydrophobicContact CE2-CG2 3.59Å; Y127-V131 HydrophobicContact CG-CG2 4.46Å; Y127-V131 WeakPolarHBondContact O-CB 2.97Å; Y127-V131 PolarHBondContact O-N 2.76Å; V131-I217 HydrophobicContact CG2-CG1 4.26Å
132	H	85.4	Confident	85.6	Confident	86 Å²	86	57.2 Å²	57.2	40%	0.398	30%	0.302	S	S	.	.			trans	-121.8	51.9	-175.4	-61.8	-69.8	0	0	0	112.1	Y127 L128 V134 F135 A136	Y127-H132 AromaticContact CE1-CD2 3.71Å; Y127-H132 AromaticContact CE1-NE2 3.84Å; L128-H132 HydrophobicContact CD2-CB 4.43Å; L128-H132 CarbonylContact O-C 3.57Å; L128-H132 WeakPolarHBondContact O-CA 3.36Å; L128-H132 PolarHBondContact O-N 3.48Å; H132-V134 VanDerWaalsContact C-N 3.29Å; H132-V134 PolarHBondContact O-N 3.1Å; H132-V134 VanDerWaalsContact O-N 3.15Å; H132-F135 HydrophobicContact CB-CB 4.28Å; H132-F135 PolarHBondContact O-N 3.15Å; H132-F135 VanDerWaalsContact O-N 3.14Å; H132-A136 VanDerWaalsContact O-CB 3.3Å; H132-A136 WeakPolarHBondContact O-CB 3.28Å; H132-A136 PolarHBondContact O-N 3.23Å
133	A	80.4	Confident	85.5	Confident	57 Å²	57	62.1 Å²	62.1	47%	0.471	33%	0.332	S	S	.	.	H	α-helix	trans	-54.5	-36.7	-171.3	0	0	0	0	0	114.9	A136 L137	A133-A136 WeakPolarHBondContact O-CB 3.48Å; A133-L137 PolarHBondContact O-N 2.97Å
134	V	78.8	Confident	85.5	Confident	127 Å²	127	67.7 Å²	67.7	77%	0.77	36%	0.357	S	S	*	.	H	α-helix	trans	-69.6	-45.9	179.1	-179.3	0	0	0	0	111.4	H132 A136 L137	H132-V134 VanDerWaalsContact C-N 3.29Å; H132-V134 PolarHBondContact O-N 3.1Å; H132-V134 VanDerWaalsContact O-N 3.15Å; V134-A136 VanDerWaalsContact C-N 3.31Å; V134-A136 PolarHBondContact O-N 3.33Å; V134-L137 PolarHBondContact O-N 3.48Å
135	F	78.7	Confident	85.5	Confident	129 Å²	129	64.9 Å²	64.9	57%	0.566	34%	0.342	S	S	*	.	H	α-helix	trans	-64.7	-38.5	175.2	177.5	-100.2	0	0	0	111.6	L128 H132 L137 K138 A139	L128-F135 HydrophobicContact CD2-CD1 4.33Å; L128-F135 HydrophobicContact CD2-CE1 4.46Å; H132-F135 HydrophobicContact CB-CB 4.28Å; H132-F135 PolarHBondContact O-N 3.15Å; H132-F135 VanDerWaalsContact O-N 3.14Å; F135-L137 VanDerWaalsContact C-N 3.26Å; F135-L137 PolarHBondContact O-N 3.41Å; F135-K138 PolarHBondContact O-N 3.29Å; F135-K138 VanDerWaalsContact O-N 3.08Å; F135-A139 HydrophobicContact CD1-CB 4.07Å; F135-A139 HydrophobicContact CE1-CB 3.6Å; F135-A139 HydrophobicContact CZ-CB 3.87Å; F135-A139 PolarHBondContact O-N 3.05Å
136	A	76.8	Confident	85.7	Confident	6 Å²	6	68 Å²	68	5%	0.05	36%	0.361	C	S	.	.	H	α-helix	trans	-59.1	-31.8	179.4	0	0	0	0	0	113.6	L128 H132 A133 V134 K138 R140	L128-A136 WeakPolarHBondContact O-CB 3.45Å; H132-A136 VanDerWaalsContact O-CB 3.3Å; H132-A136 WeakPolarHBondContact O-CB 3.28Å; H132-A136 PolarHBondContact O-N 3.23Å; A133-A136 WeakPolarHBondContact O-CB 3.48Å; V134-A136 VanDerWaalsContact C-N 3.31Å; V134-A136 PolarHBondContact O-N 3.33Å; A136-K138 VanDerWaalsContact C-N 3.28Å; A136-K138 PolarHBondContact O-N 3.34Å; A136-R140 HydrophobicContact CB-CG 4.29Å; A136-R140 VanDerWaalsContact O-CB 3.24Å; A136-R140 WeakPolarHBondContact O-CB 3.47Å; A136-R140 VanDerWaalsContact O-CG 3.31Å; A136-R140 WeakPolarHBondContact O-CG 3.48Å; A136-R140 PolarHBondContact O-N 3.09Å; A136-R140 VanDerWaalsContact O-N 3.12Å
137	L	77.2	Confident	86.1	Confident	151 Å²	151	70 Å²	70	79%	0.791	38%	0.377	S	S	*	.	H	α-helix	trans	-61.8	-35.3	175.7	-77.5	158.7	0	0	0	112.5	A133 V134 F135	A133-L137 PolarHBondContact O-N 2.97Å; V134-L137 PolarHBondContact O-N 3.48Å; F135-L137 VanDerWaalsContact C-N 3.26Å; F135-L137 PolarHBondContact O-N 3.41Å
138	K	78.1	Confident	86.4	Confident	175 Å²	175	69.5 Å²	69.5	76%	0.761	38%	0.379	S	S	*	.	H	α-helix	trans	-88.1	-36.9	-179.2	-170.4	176.4	179.9	179.1	0	112.7	F135 A136	F135-K138 PolarHBondContact O-N 3.29Å; F135-K138 VanDerWaalsContact O-N 3.08Å; A136-K138 VanDerWaalsContact C-N 3.28Å; A136-K138 PolarHBondContact O-N 3.34Å
139	A	77.6	Confident	86.8	Confident	25 Å²	25	67.7 Å²	67.7	21%	0.207	37%	0.37	C	S	.	.	H	α-helix	trans	-88.4	-22.4	-171.5	0	0	0	0	0	114.6	F135 T141	F135-A139 HydrophobicContact CD1-CB 4.07Å; F135-A139 HydrophobicContact CE1-CB 3.6Å; F135-A139 HydrophobicContact CZ-CB 3.87Å; F135-A139 PolarHBondContact O-N 3.05Å; A139-T141 VanDerWaalsContact C-N 3.32Å; A139-T141 PolarHBondContact O-N 2.92Å
140	R	86.5	Confident	87.3	Confident	65 Å²	65	70.6 Å²	70.6	25%	0.245	39%	0.385	C	S	.	.			trans	-95	45.6	-171.8	-60.2	173.8	66.5	-115.4	-29.6	113.4	M64 D125 A136	M64-R140 HydrophobicContact SD-CB 4Å; M64-R140 HydrophobicContact SD-CG 4.19Å; D125-R140 PolarHBondContact O-NE 3.47Å; D125-R140 IonicContact OD1-CZ 3.16Å; D125-R140 IonicContact OD1-NE 2.71Å; D125-R140 PolarHBondContact OD1-NE 3.45Å; D125-R140 IonicContact OD1-NH2 2.78Å; D125-R140 PolarHBondContact OD1-NH2 3.41Å; D125-R140 IonicContact OD2-NH2 3.57Å; A136-R140 HydrophobicContact CB-CG 4.29Å; A136-R140 VanDerWaalsContact O-CB 3.24Å; A136-R140 WeakPolarHBondContact O-CB 3.47Å; A136-R140 VanDerWaalsContact O-CG 3.31Å; A136-R140 WeakPolarHBondContact O-CG 3.48Å; A136-R140 PolarHBondContact O-N 3.09Å; A136-R140 VanDerWaalsContact O-N 3.12Å
141	T	88.6	Confident	88	Confident	54 Å²	54	74.6 Å²	74.6	33%	0.331	41%	0.405	S	S	.	.			trans	-81.7	157.1	175.9	73.2	0	0	0	0	111	A139 T143 F144 G145	A139-T141 VanDerWaalsContact C-N 3.32Å; A139-T141 PolarHBondContact O-N 2.92Å; T141-T143 VanDerWaalsContact C-N 3.26Å; T141-T143 PolarHBondContact O-N 2.96Å; T141-F144 HydrophobicContact CG2-CD2 4.4Å; T141-F144 PolarHBondContact O-N 3.14Å; T141-F144 WeakPolarHBondContact OG1-CD2 3.17Å; T141-F144 PolarHBondContact OG1-N 3.41Å; T141-G145 PolarHBondContact O-N 3.39Å; T141-G145 VanDerWaalsContact O-N 3.1Å
142	V	90.8	Very high	88.5	Confident	57 Å²	57	73.6 Å²	73.6	35%	0.345	40%	0.399	S	S	.	.	H	α-helix	trans	-61.6	-38.1	176.4	175.4	0	0	0	0	110.9	I67 F144 G145 V146	I67-V142 HydrophobicContact CD1-CG1 4.19Å; I67-V142 HydrophobicContact CG1-CG1 4.2Å; V142-F144 PolarHBondContact O-N 2.64Å; V142-G145 WeakPolarHBondContact O-CA 3.29Å; V142-G145 PolarHBondContact O-N 3.13Å; V142-G145 VanDerWaalsContact O-N 3.14Å; V142-V146 HydrophobicContact CG1-CG2 4.42Å; V142-V146 WeakPolarHBondContact O-CG2 3.38Å; V142-V146 PolarHBondContact O-N 3.27Å
143	T	92.1	Very high	89.1	Confident	105 Å²	105	71.7 Å²	71.7	64%	0.644	39%	0.388	S	S	*	.	H	α-helix	trans	-58.8	-48.3	177.4	-46.9	0	0	0	0	111.8	T141 G145 V146 V147	T141-T143 VanDerWaalsContact C-N 3.26Å; T141-T143 PolarHBondContact O-N 2.96Å; T143-G145 VanDerWaalsContact C-N 3.31Å; T143-G145 PolarHBondContact O-N 3Å; T143-V146 PolarHBondContact O-N 2.94Å; T143-V147 WeakPolarHBondContact O-CG2 3.47Å; T143-V147 PolarHBondContact O-N 3.42Å
144	F	92.4	Very high	90	Very high	117 Å²	117	72.5 Å²	72.5	51%	0.513	39%	0.387	S	S	.	.	H	α-helix	trans	-61.1	-42.7	175.1	-81	-63.1	0	0	0	111.2	T141 V142 V146 V147 T148	T141-F144 HydrophobicContact CG2-CD2 4.4Å; T141-F144 PolarHBondContact O-N 3.14Å; T141-F144 WeakPolarHBondContact OG1-CD2 3.17Å; T141-F144 PolarHBondContact OG1-N 3.41Å; V142-F144 PolarHBondContact O-N 2.64Å; F144-V146 VanDerWaalsContact C-N 3.35Å; F144-V146 PolarHBondContact O-N 3.27Å; F144-V147 PolarHBondContact O-N 3Å; F144-T148 WeakPolarHBondContact O-CB 3.34Å; F144-T148 WeakPolarHBondContact O-CG2 3.27Å; F144-T148 PolarHBondContact O-N 2.98Å; F144-T148 PolarHBondContact O-OG1 2.97Å
145	G	93.5	Very high	90.9	Very high	0 Å²	0	69.8 Å²	69.8	0%	0	37%	0.371	C	S	.	.	H	α-helix	trans	-53.4	-47.2	174.1	0	0	0	0	0	113.6	T141 V142 T143 T148 S149	T141-G145 PolarHBondContact O-N 3.39Å; T141-G145 VanDerWaalsContact O-N 3.1Å; V142-G145 WeakPolarHBondContact O-CA 3.29Å; V142-G145 PolarHBondContact O-N 3.13Å; V142-G145 VanDerWaalsContact O-N 3.14Å; T143-G145 VanDerWaalsContact C-N 3.31Å; T143-G145 PolarHBondContact O-N 3Å; G145-T148 WeakPolarHBondContact CA-OG1 3.46Å; G145-T148 PolarHBondContact O-OG1 3.4Å; G145-S149 WeakPolarHBondContact O-CB 3.37Å; G145-S149 PolarHBondContact O-N 2.91Å; G145-S149 PolarHBondContact O-OG 3.49Å; G145-S149 VanDerWaalsContact O-OG 3.1Å
146	V	95.8	Very high	91.8	Very high	70 Å²	70	63.7 Å²	63.7	42%	0.424	34%	0.344	S	S	.	.	H	α-helix	trans	-64.3	-48.3	178.2	173.7	0	0	0	0	111.2	V142 T143 F144 T148 S149 V150	V142-V146 HydrophobicContact CG1-CG2 4.42Å; V142-V146 WeakPolarHBondContact O-CG2 3.38Å; V142-V146 PolarHBondContact O-N 3.27Å; T143-V146 PolarHBondContact O-N 2.94Å; F144-V146 VanDerWaalsContact C-N 3.35Å; F144-V146 PolarHBondContact O-N 3.27Å; V146-T148 PolarHBondContact O-N 3.48Å; V146-S149 WeakPolarHBondContact O-CB 3.26Å; V146-S149 PolarHBondContact O-N 3.44Å; V146-V150 WeakPolarHBondContact O-CG2 3.38Å; V146-V150 PolarHBondContact O-N 2.83Å
147	V	96.6	Very high	92.8	Very high	77 Å²	77	66.3 Å²	66.3	47%	0.467	36%	0.359	S	S	.	.	H	α-helix	trans	-59.9	-46.8	179.4	173.2	0	0	0	0	110.9	T143 F144 S149 V150 I151	T143-V147 WeakPolarHBondContact O-CG2 3.47Å; T143-V147 PolarHBondContact O-N 3.42Å; F144-V147 PolarHBondContact O-N 3Å; V147-S149 VanDerWaalsContact C-N 3.32Å; V147-S149 PolarHBondContact O-N 3.13Å; V147-V150 PolarHBondContact O-N 3.2Å; V147-I151 HydrophobicContact CG1-CD1 4.01Å; V147-I151 WeakPolarHBondContact O-CG1 3.35Å; V147-I151 PolarHBondContact O-N 2.91Å; V147-I151 VanDerWaalsContact O-N 3.08Å
148	T	96.8	Very high	93.8	Very high	39 Å²	39	65.5 Å²	65.5	24%	0.239	35%	0.35	C	S	.	.	H	α-helix	trans	-62.1	-39.4	176.8	48.7	0	0	0	0	112.1	Y68 F144 G145 V146 I151 T152	Y68-T148 WeakPolarHBondContact CE1-OG1 3.46Å; Y68-T148 PolarHBondContact OH-OG1 3.27Å; F144-T148 WeakPolarHBondContact O-CB 3.34Å; F144-T148 WeakPolarHBondContact O-CG2 3.27Å; F144-T148 PolarHBondContact O-N 2.98Å; F144-T148 PolarHBondContact O-OG1 2.97Å; G145-T148 WeakPolarHBondContact CA-OG1 3.46Å; G145-T148 PolarHBondContact O-OG1 3.4Å; V146-T148 PolarHBondContact O-N 3.48Å; T148-I151 PolarHBondContact O-N 3.32Å; T148-T152 WeakPolarHBondContact O-CB 3.4Å; T148-T152 PolarHBondContact O-N 3.44Å; T148-T152 PolarHBondContact O-OG1 3.31Å
149	S	97.8	Very high	94.6	Very high	4 Å²	4	57.9 Å²	57.9	3%	0.028	32%	0.319	C	S	.	.	H	α-helix	trans	-62.9	-43.4	176	-70.6	0	0	0	0	112.3	N71 F118 G145 V146 V147 I151 T152 W153	N71-S149 PolarHBondContact ND2-OG 3.13Å; F118-S149 WeakPolarHBondContact CE1-OG 3.28Å; G145-S149 WeakPolarHBondContact O-CB 3.37Å; G145-S149 PolarHBondContact O-N 2.91Å; G145-S149 PolarHBondContact O-OG 3.49Å; G145-S149 VanDerWaalsContact O-OG 3.1Å; V146-S149 WeakPolarHBondContact O-CB 3.26Å; V146-S149 PolarHBondContact O-N 3.44Å; V147-S149 VanDerWaalsContact C-N 3.32Å; V147-S149 PolarHBondContact O-N 3.13Å; S149-I151 VanDerWaalsContact C-N 3.34Å; S149-I151 PolarHBondContact O-N 3.02Å; S149-T152 WeakPolarHBondContact O-CB 3.14Å; S149-T152 PolarHBondContact O-N 3.41Å; S149-W153 PolarHBondContact O-N 3.32Å
150	V	98.2	Very high	95.5	Very high	86 Å²	86	56.7 Å²	56.7	52%	0.521	31%	0.31	S	S	.	.	H	α-helix	trans	-60.5	-45.8	177.5	172.1	0	0	0	0	110.6	V146 V147 T152 W153 V154	V146-V150 WeakPolarHBondContact O-CG2 3.38Å; V146-V150 PolarHBondContact O-N 2.83Å; V147-V150 PolarHBondContact O-N 3.2Å; V150-T152 VanDerWaalsContact C-N 3.32Å; V150-T152 PolarHBondContact O-N 2.86Å; V150-W153 PolarHBondContact O-N 3.31Å; V150-V154 WeakPolarHBondContact O-CG2 3.24Å; V150-V154 PolarHBondContact O-N 3.43Å
151	I	98.3	Very high	95.8	Very high	99 Å²	99	56.8 Å²	56.8	51%	0.508	31%	0.314	S	S	.	.	H	α-helix	trans	-59.7	-45.2	175.9	-65.4	166.8	0	0	0	110.3	V147 T148 S149 W153 V154 V155	V147-I151 HydrophobicContact CG1-CD1 4.01Å; V147-I151 WeakPolarHBondContact O-CG1 3.35Å; V147-I151 PolarHBondContact O-N 2.91Å; V147-I151 VanDerWaalsContact O-N 3.08Å; T148-I151 PolarHBondContact O-N 3.32Å; S149-I151 VanDerWaalsContact C-N 3.34Å; S149-I151 PolarHBondContact O-N 3.02Å; I151-W153 VanDerWaalsContact C-N 3.34Å; I151-W153 PolarHBondContact O-N 2.9Å; I151-V154 PolarHBondContact O-N 3.14Å; I151-V155 HydrophobicContact CG2-CG2 4.31Å; I151-V155 WeakPolarHBondContact O-CG2 3.4Å; I151-V155 PolarHBondContact O-N 3.19Å
152	T	98.3	Very high	96	Very high	16 Å²	16	55.4 Å²	55.4	10%	0.098	31%	0.307	C	S	.	.	H	α-helix	trans	-60.3	-40.8	178.2	-64.2	0	0	0	0	112.8	F117 F118 L121 T148 S149 V150 V155 A156	F117-T152 HydrophobicContact CB-CG2 3.51Å; F117-T152 HydrophobicContact CD2-CG2 4.15Å; F117-T152 HydrophobicContact CG-CG2 4.32Å; F118-T152 HydrophobicContact CD2-CG2 4.42Å; F118-T152 HydrophobicContact CE1-CG2 4.1Å; F118-T152 HydrophobicContact CE2-CG2 3.97Å; F118-T152 HydrophobicContact CZ-CG2 3.78Å; L121-T152 HydrophobicContact CD1-CG2 4.41Å; L121-T152 VanDerWaalsContact CD1-OG1 3.32Å; L121-T152 WeakPolarHBondContact CD1-OG1 3.27Å; T148-T152 WeakPolarHBondContact O-CB 3.4Å; T148-T152 PolarHBondContact O-N 3.44Å; T148-T152 PolarHBondContact O-OG1 3.31Å; S149-T152 WeakPolarHBondContact O-CB 3.14Å; S149-T152 PolarHBondContact O-N 3.41Å; V150-T152 VanDerWaalsContact C-N 3.32Å; V150-T152 PolarHBondContact O-N 2.86Å; T152-V155 PolarHBondContact O-N 3.31Å; T152-A156 WeakPolarHBondContact O-CB 3.26Å; T152-A156 PolarHBondContact O-N 2.89Å
153	W	98.4	Very high	95.9	Very high	47 Å²	47	52.7 Å²	52.7	18%	0.178	29%	0.29	C	S	.	.	H	α-helix	trans	-62	-45.6	174.6	-81	112.9	0	0	0	112.1	N71 I74 F78 I110 S114 F118 S149 V150 I151 V155 A156 V157	N71-W153 PolarHBondContact OD1-NE1 3.3Å; I74-W153 HydrophobicContact CB-CZ2 4.27Å; I74-W153 HydrophobicContact CG2-CH2 3.99Å; I74-W153 HydrophobicContact CG2-CZ2 3.78Å; F78-W153 AromaticContact CD2-CH2 3.53Å; F78-W153 HydrophobicContact CD2-CH2 3.53Å; F78-W153 AromaticContact CD2-CZ3 3.55Å; F78-W153 HydrophobicContact CD2-CZ3 3.55Å; F78-W153 HydrophobicContact CE2-CE3 4.33Å; F78-W153 AromaticContact CE2-CH2 3.42Å; F78-W153 HydrophobicContact CE2-CH2 3.42Å; F78-W153 VanDerWaalsContact CE2-CH2 3.42Å; F78-W153 HydrophobicContact CE2-CZ2 4.34Å; F78-W153 AromaticContact CE2-CZ3 3.42Å; F78-W153 HydrophobicContact CE2-CZ3 3.42Å; F78-W153 VanDerWaalsContact CE2-CZ3 3.42Å; I110-W153 HydrophobicContact CG2-CE3 4.09Å; I110-W153 HydrophobicContact CG2-CZ3 3.61Å; S114-W153 WeakPolarHBondContact OG-CZ3 3.26Å; F118-W153 AromaticContact CE2-CE2 3.94Å; F118-W153 HydrophobicContact CE2-CZ2 4.17Å; F118-W153 AromaticContact CE2-NE1 3.91Å; F118-W153 AromaticContact CZ-NE1 3.77Å; S149-W153 PolarHBondContact O-N 3.32Å; V150-W153 PolarHBondContact O-N 3.31Å; I151-W153 VanDerWaalsContact C-N 3.34Å; I151-W153 PolarHBondContact O-N 2.9Å; W153-V155 VanDerWaalsContact C-N 3.34Å; W153-V155 PolarHBondContact O-N 3Å; W153-A156 PolarHBondContact O-N 2.85Å; W153-V157 WeakPolarHBondContact O-CG2 3.45Å; W153-V157 PolarHBondContact O-N 3.44Å
154	V	98.3	Very high	95.9	Very high	73 Å²	73	49.7 Å²	49.7	44%	0.442	27%	0.27	S	S	.	.	H	α-helix	trans	-58.9	-47.3	176.4	172.6	0	0	0	0	110.5	V150 I151 A156 V157 F158	V150-V154 WeakPolarHBondContact O-CG2 3.24Å; V150-V154 PolarHBondContact O-N 3.43Å; I151-V154 PolarHBondContact O-N 3.14Å; V154-A156 PolarHBondContact O-N 3.19Å; V154-V157 PolarHBondContact O-N 2.86Å; V154-F158 HydrophobicContact CG1-CD2 3.66Å; V154-F158 HydrophobicContact CG1-CE2 3.51Å; V154-F158 WeakPolarHBondContact O-CD2 3.42Å; V154-F158 PolarHBondContact O-N 2.97Å
155	V	98.1	Very high	95.9	Very high	71 Å²	71	49 Å²	49	43%	0.43	27%	0.27	S	S	.	.	H	α-helix	trans	-61.5	-41.3	177.2	174.9	0	0	0	0	111.8	F117 I151 T152 W153 V157 F158 A159	F117-V155 HydrophobicContact CD2-CG1 4.49Å; F117-V155 HydrophobicContact CE2-CG1 3.82Å; F117-V155 HydrophobicContact CZ-CG1 4.33Å; I151-V155 HydrophobicContact CG2-CG2 4.31Å; I151-V155 WeakPolarHBondContact O-CG2 3.4Å; I151-V155 PolarHBondContact O-N 3.19Å; T152-V155 PolarHBondContact O-N 3.31Å; W153-V155 VanDerWaalsContact C-N 3.34Å; W153-V155 PolarHBondContact O-N 3Å; V155-V157 PolarHBondContact O-N 3.25Å; V155-F158 PolarHBondContact O-N 3.02Å; V155-A159 WeakPolarHBondContact O-CB 3.24Å; V155-A159 PolarHBondContact O-N 3.44Å
156	A	97.9	Very high	95.9	Very high	0 Å²	0	50.1 Å²	50.1	0%	0	28%	0.275	C	S	.	.	H	α-helix	trans	-64.3	-38.6	177.4	0	0	0	0	0	112.3	F113 F117 T152 W153 V154 A159 S160	F113-A156 HydrophobicContact CB-CB 4.15Å; F117-A156 HydrophobicContact CD2-CB 4.36Å; F117-A156 HydrophobicContact CE2-CB 4.47Å; T152-A156 WeakPolarHBondContact O-CB 3.26Å; T152-A156 PolarHBondContact O-N 2.89Å; W153-A156 PolarHBondContact O-N 2.85Å; V154-A156 PolarHBondContact O-N 3.19Å; A156-A159 PolarHBondContact O-N 3.41Å; A156-S160 WeakPolarHBondContact O-CB 3.43Å; A156-S160 PolarHBondContact O-N 3.23Å; A156-S160 VanDerWaalsContact O-N 3.13Å; A156-S160 PolarHBondContact O-OG 3.02Å
157	V	97.8	Very high	95.7	Very high	61 Å²	61	47 Å²	47	37%	0.37	26%	0.256	S	S	.	.	H	α-helix	trans	-63.1	-50.6	173.4	172.1	0	0	0	0	110.4	I110 W153 V154 V155 A159 S160 L161	I110-V157 HydrophobicContact CD1-CG2 3.98Å; I110-V157 HydrophobicContact CG1-CG2 4.22Å; W153-V157 WeakPolarHBondContact O-CG2 3.45Å; W153-V157 PolarHBondContact O-N 3.44Å; V154-V157 PolarHBondContact O-N 2.86Å; V155-V157 PolarHBondContact O-N 3.25Å; V157-A159 VanDerWaalsContact C-N 3.32Å; V157-A159 PolarHBondContact O-N 3.45Å; V157-S160 WeakPolarHBondContact O-CA 3.28Å; V157-S160 WeakPolarHBondContact O-CB 3.45Å; V157-S160 PolarHBondContact O-N 2.98Å; V157-L161 PolarHBondContact O-N 2.76Å; V157-L161 VanDerWaalsContact O-N 3.09Å
158	F	97.2	Very high	95.5	Very high	135 Å²	135	50.2 Å²	50.2	59%	0.592	26%	0.26	S	S	*	.	H	α-helix	trans	-58.5	-41.8	177.6	-83.1	-69.8	0	0	0	112.7	V154 V155 S160 L161	V154-F158 HydrophobicContact CG1-CD2 3.66Å; V154-F158 HydrophobicContact CG1-CE2 3.51Å; V154-F158 WeakPolarHBondContact O-CD2 3.42Å; V154-F158 PolarHBondContact O-N 2.97Å; V155-F158 PolarHBondContact O-N 3.02Å; F158-S160 PolarHBondContact O-N 2.85Å; F158-L161 HydrophobicContact CD1-CD1 3.64Å; F158-L161 HydrophobicContact CE1-CD1 4.11Å; F158-L161 HydrophobicContact CG-CD1 4.47Å; F158-L161 PolarHBondContact O-N 2.96Å
159	A	95.9	Very high	95.3	Very high	15 Å²	15	49.5 Å²	49.5	12%	0.124	26%	0.257	C	S	.	.	H	α-helix	trans	-63.6	-26	176.1	0	0	0	0	0	112.9	F113 V155 A156 V157 K197 L201	F113-A159 HydrophobicContact CD1-CB 4.39Å; F113-A159 HydrophobicContact CD2-CB 3.8Å; F113-A159 HydrophobicContact CE2-CB 4.12Å; F113-A159 HydrophobicContact CG-CB 3.99Å; V155-A159 WeakPolarHBondContact O-CB 3.24Å; V155-A159 PolarHBondContact O-N 3.44Å; A156-A159 PolarHBondContact O-N 3.41Å; V157-A159 VanDerWaalsContact C-N 3.32Å; V157-A159 PolarHBondContact O-N 3.45Å; A159-K197 PolarHBondContact O-NZ 3.4Å; A159-L201 HydrophobicContact CB-CD1 4.31Å
160	S	95.9	Very high	94.9	Very high	0 Å²	0	53.1 Å²	53.1	0%	0	27%	0.273	C	S	.	.	H	α-helix	trans	-85.4	-25.6	-179.9	-56.2	0	0	0	0	113.4	F109 I110 A156 V157 F158 G163 I164	F109-S160 WeakPolarHBondContact CB-OG 3.26Å; F109-S160 PolarHBondContact O-OG 2.94Å; I110-S160 WeakPolarHBondContact CA-OG 3.34Å; I110-S160 WeakPolarHBondContact CG1-OG 3.28Å; I110-S160 PolarHBondContact N-OG 2.71Å; I110-S160 VanDerWaalsContact N-OG 3.13Å; A156-S160 WeakPolarHBondContact O-CB 3.43Å; A156-S160 PolarHBondContact O-N 3.23Å; A156-S160 VanDerWaalsContact O-N 3.13Å; A156-S160 PolarHBondContact O-OG 3.02Å; V157-S160 WeakPolarHBondContact O-CA 3.28Å; V157-S160 WeakPolarHBondContact O-CB 3.45Å; V157-S160 PolarHBondContact O-N 2.98Å; F158-S160 PolarHBondContact O-N 2.85Å; S160-G163 WeakPolarHBondContact O-CA 3.26Å; S160-G163 PolarHBondContact O-N 2.99Å; S160-I164 PolarHBondContact O-N 2.92Å
161	L	94.1	Very high	94.5	Very high	66 Å²	66	55.1 Å²	55.1	35%	0.346	28%	0.275	S	S	.	.	H	α-helix	trans	-51.4	-46.2	-174.7	-71.7	176.3	0	0	0	114.6	V157 F158 G163 I164 I165	V157-L161 PolarHBondContact O-N 2.76Å; V157-L161 VanDerWaalsContact O-N 3.09Å; F158-L161 HydrophobicContact CD1-CD1 3.64Å; F158-L161 HydrophobicContact CE1-CD1 4.11Å; F158-L161 HydrophobicContact CG-CD1 4.47Å; F158-L161 PolarHBondContact O-N 2.96Å; L161-G163 PolarHBondContact O-N 3.09Å; L161-I164 PolarHBondContact O-N 2.82Å; L161-I164 VanDerWaalsContact O-N 3.13Å; L161-I165 VanDerWaalsContact O-CG1 3.31Å; L161-I165 WeakPolarHBondContact O-CG1 2.98Å; L161-I165 PolarHBondContact O-N 2.69Å
162	P	91.1	Very high	93.7	Very high	26 Å²	26	54.4 Å²	54.4	17%	0.169	27%	0.269	C	S	.	.	H	α-helix	trans	-60.2	-37.3	178.8	-23.8	34.6	0	0	0	112.2	I165 F166 F193	P162-I165 PolarHBondContact O-N 3.33Å; P162-F166 HydrophobicContact CB-CD2 4.39Å; P162-F166 HydrophobicContact CB-CE2 4.27Å; P162-F166 WeakPolarHBondContact O-CD2 3.45Å; P162-F166 PolarHBondContact O-N 3.24Å; P162-F166 VanDerWaalsContact O-N 3.13Å; P162-F193 HydrophobicContact CB-CE1 4.49Å; P162-F193 HydrophobicContact CG-CE1 4.23Å
163	G	88.9	Confident	93	Very high	0 Å²	0	56.8 Å²	56.8	0%	0	30%	0.297	C	S	.	.	H	α-helix	trans	-62.1	-45.8	176.1	0	0	0	0	0	111.5	S160 L161 I165 F166 T167	S160-G163 WeakPolarHBondContact O-CA 3.26Å; S160-G163 PolarHBondContact O-N 2.99Å; L161-G163 PolarHBondContact O-N 3.09Å; G163-I165 VanDerWaalsContact C-N 3.35Å; G163-I165 PolarHBondContact O-N 3.46Å; G163-F166 PolarHBondContact O-N 3.03Å; G163-T167 VanDerWaalsContact O-CB 3.28Å; G163-T167 WeakPolarHBondContact O-CB 3.49Å; G163-T167 PolarHBondContact O-N 2.93Å; G163-T167 PolarHBondContact O-OG1 3.02Å
164	I	92.4	Very high	92.2	Very high	42 Å²	42	61.9 Å²	61.9	22%	0.215	33%	0.327	C	S	.	.	H	α-helix	trans	-62.5	-41.5	179.7	-59	168.9	0	0	0	111.6	Q102 G106 S160 L161	Q102-I164 HydrophobicContact CB-CG2 4.23Å; G106-I164 VanDerWaalsContact CA-CG1 3.47Å; S160-I164 PolarHBondContact O-N 2.92Å; L161-I164 PolarHBondContact O-N 2.82Å; L161-I164 VanDerWaalsContact O-N 3.13Å
165	I	92.9	Very high	91.6	Very high	103 Å²	103	62.2 Å²	62.2	53%	0.528	32%	0.324	S	S	.	.	H	α-helix	trans	-69.1	-42.2	-176.7	-66.7	164.3	0	0	0	111.5	L161 P162 G163	L161-I165 VanDerWaalsContact O-CG1 3.31Å; L161-I165 WeakPolarHBondContact O-CG1 2.98Å; L161-I165 PolarHBondContact O-N 2.69Å; P162-I165 PolarHBondContact O-N 3.33Å; G163-I165 VanDerWaalsContact C-N 3.35Å; G163-I165 PolarHBondContact O-N 3.46Å
166	F	92.6	Very high	91.3	Very high	23 Å²	23	64.1 Å²	64.1	10%	0.101	32%	0.324	C	S	.	.	H	α-helix	trans	-84.9	-20	-176.6	-64.6	-56.9	0	0	0	113.3	P162 G163 H181 F182 P183 W190	P162-F166 HydrophobicContact CB-CD2 4.39Å; P162-F166 HydrophobicContact CB-CE2 4.27Å; P162-F166 WeakPolarHBondContact O-CD2 3.45Å; P162-F166 PolarHBondContact O-N 3.24Å; P162-F166 VanDerWaalsContact O-N 3.13Å; G163-F166 PolarHBondContact O-N 3.03Å; F166-H181 PolarHBondContact O-N 2.78Å; F166-F182 HydrophobicContact CB-CD1 3.85Å; F166-F182 HydrophobicContact CB-CE1 3.82Å; F166-F182 HydrophobicContact CD1-CD1 4.03Å; F166-F182 AromaticContact CD2-CD1 3.82Å; F166-F182 HydrophobicContact CD2-CD1 3.82Å; F166-F182 AromaticContact CD2-CE1 3.77Å; F166-F182 HydrophobicContact CD2-CE1 3.77Å; F166-F182 HydrophobicContact CE2-CD1 4.45Å; F166-F182 AromaticContact CG-CD1 3.62Å; F166-F182 HydrophobicContact CG-CD1 3.62Å; F166-F182 AromaticContact CG-CE1 3.85Å; F166-F182 HydrophobicContact CG-CE1 3.85Å; F166-P183 HydrophobicContact CE1-CG 3.98Å; F166-W190 HydrophobicContact CD2-CE3 4.4Å; F166-W190 HydrophobicContact CE1-CD2 4.32Å; F166-W190 AromaticContact CE2-CD2 3.73Å; F166-W190 HydrophobicContact CE2-CD2 3.73Å; F166-W190 AromaticContact CE2-CE3 3.28Å; F166-W190 HydrophobicContact CE2-CE3 3.28Å; F166-W190 HydrophobicContact CE2-CG 4.38Å; F166-W190 HydrophobicContact CE2-CH2 4.21Å; F166-W190 AromaticContact CE2-CZ3 3.56Å; F166-W190 HydrophobicContact CE2-CZ3 3.56Å; F166-W190 AromaticContact CZ-CD2 3.42Å; F166-W190 HydrophobicContact CZ-CD2 3.42Å; F166-W190 VanDerWaalsContact CZ-CD2 3.42Å; F166-W190 AromaticContact CZ-CE2 3.65Å; F166-W190 AromaticContact CZ-CE3 3.45Å; F166-W190 HydrophobicContact CZ-CE3 3.45Å; F166-W190 VanDerWaalsContact CZ-CE3 3.45Å; F166-W190 HydrophobicContact CZ-CG 4.02Å; F166-W190 AromaticContact CZ-CH2 3.9Å; F166-W190 HydrophobicContact CZ-CH2 3.9Å; F166-W190 AromaticContact CZ-CZ2 3.89Å; F166-W190 HydrophobicContact CZ-CZ2 3.89Å; F166-W190 AromaticContact CZ-CZ3 3.69Å; F166-W190 HydrophobicContact CZ-CZ3 3.69Å
167	T	92.6	Very high	90.9	Very high	4 Å²	4	64.9 Å²	64.9	3%	0.025	33%	0.329	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-79.3	130.2	176.6	-61.4	0	0	0	0	111.6	C101 Q102 T105 G163 S179 S180	C101-T167 WeakPolarHBondContact SG-CG2 3.38Å; Q102-T167 WeakPolarHBondContact CG-O 3.47Å; Q102-T167 PolarHBondContact NE2-O 3.35Å; T105-T167 HydrophobicContact CG2-CG2 4.14Å; T105-T167 WeakPolarHBondContact OG1-CG2 3.44Å; G163-T167 VanDerWaalsContact O-CB 3.28Å; G163-T167 WeakPolarHBondContact O-CB 3.49Å; G163-T167 PolarHBondContact O-N 2.93Å; G163-T167 PolarHBondContact O-OG1 3.02Å; T167-S179 WeakPolarHBondContact CA-O 3.35Å; T167-S180 PolarHBondContact OG1-OG 3.2Å; T167-S180 VanDerWaalsContact OG1-OG 3.13Å
168	R	92.6	Very high	90.7	Very high	144 Å²	144	62.5 Å²	62.5	54%	0.543	32%	0.315	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-140.6	156.5	178.1	-63.7	-170.9	179.4	-161.1	-0.7	110.6	N98 S179	N98-R168 VanDerWaalsContact OD1-CA 3.28Å; N98-R168 WeakPolarHBondContact OD1-CA 3.26Å; R168-S179 PolarHBondContact N-O 3.22Å; R168-S179 PolarHBondContact O-N 3.33Å; R168-S179 VanDerWaalsContact O-N 3.12Å
169	S	92.8	Very high	90.4	Very high	25 Å²	25	57.7 Å²	57.7	18%	0.175	30%	0.298	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-96.4	125.9	166.4	-174.9	0	0	0	0	110.6	N98 T177	N98-S169 PolarHBondContact OD1-N 3.43Å; S169-T177 WeakPolarHBondContact CA-O 3.23Å; S169-T177 WeakPolarHBondContact CB-O 3.32Å; S169-T177 PolarHBondContact OG-O 3.43Å
170	Q	89.7	Confident	90.1	Very high	80 Å²	80	59.3 Å²	59.3	37%	0.374	31%	0.308	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-143	161.2	177.5	59.8	171.2	34	0	0	111.2	E172 T177 H181	Q170-E172 HydrophobicContact CG-CG 4.14Å; Q170-E172 PolarHBondContact NE2-OE1 3.15Å; Q170-T177 PolarHBondContact N-O 3.04Å; Q170-T177 PolarHBondContact O-N 2.81Å; Q170-T177 PolarHBondContact O-OG1 3.37Å; Q170-H181 WeakPolarHBondContact CG-NE2 3.41Å; Q170-H181 PolarHBondContact NE2-CE1 2.93Å; Q170-H181 PolarHBondContact NE2-NE2 3.07Å
171	K	88.5	Confident	89.8	Confident	128 Å²	128	62 Å²	62	56%	0.557	32%	0.32	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-85.4	113.1	176.3	-170.9	178.5	179.2	-177.3	0	109.2	G173 Y176	K171-G173 WeakPolarHBondContact CE-O 3.48Å; K171-Y176 HydrophobicContact CB-CD1 4.13Å; K171-Y176 HydrophobicContact CB-CE1 3.9Å; K171-Y176 HydrophobicContact CG-CE1 4.5Å
172	E	82.5	Confident	89.6	Confident	83 Å²	83	60.3 Å²	60.3	39%	0.388	31%	0.311	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-110.3	103.2	176.5	-70.8	178.2	165.2	0	0	109	Q170 L174 H175 T177 H181	Q170-E172 HydrophobicContact CG-CG 4.14Å; Q170-E172 PolarHBondContact NE2-OE1 3.15Å; E172-L174 PolarHBondContact O-N 3.33Å; E172-H175 PolarHBondContact N-O 3.41Å; E172-H175 PolarHBondContact O-N 3.19Å; E172-T177 HydrophobicContact CB-CG2 4.23Å; E172-T177 WeakPolarHBondContact OE2-CG2 3.31Å; E172-T177 PolarHBondContact OE2-OG1 3.01Å; E172-H181 IonicContact OE1-CE1 3.68Å; E172-H181 PolarHBondContact OE1-CE1 3.05Å; E172-H181 VanDerWaalsContact OE1-CE1 3.26Å; E172-H181 IonicContact OE1-NE2 2.76Å
173	G	81.9	Confident	89.5	Confident	67 Å²	67	61.5 Å²	61.5	69%	0.691	32%	0.318	S	S	*	.	T	Hydrogen-bonded Turn	trans	66.2	-119.2	-171.5	0	0	0	0	0	111.8	K171	K171-G173 WeakPolarHBondContact CE-O 3.48Å
174	L	82.8	Confident	89.5	Confident	153 Å²	153	72.3 Å²	72.3	80%	0.801	36%	0.361	S	S	*	.	T	Hydrogen-bonded Turn	trans	-90.7	-9.2	-178.8	-69.5	168.2	0	0	0	113.8	E172	E172-L174 PolarHBondContact O-N 3.33Å
175	H	86	Confident	89.4	Confident	81 Å²	81	75.4 Å²	75.4	38%	0.375	39%	0.386	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-122.4	150.5	-170.8	-63.9	-65.8	0	0	0	112.5	Q93 E172	Q93-H175 HydrophobicContact CB-CB 4.29Å; Q93-H175 PolarHBondContact OE1-ND1 3.15Å; Q93-H175 VanDerWaalsContact OE1-ND1 3.17Å; E172-H175 PolarHBondContact N-O 3.41Å; E172-H175 PolarHBondContact O-N 3.19Å
176	Y	90.4	Very high	89.4	Confident	111 Å²	111	75.4 Å²	75.4	44%	0.435	38%	0.384	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-83.2	131.9	167.1	-72.9	-86.4	0	0	0	110.1	W94 K171	W94-Y176 WeakPolarHBondContact CB-O 3.34Å; W94-Y176 PolarHBondContact N-O 3.25Å; W94-Y176 WeakPolarHBondContact O-CB 3.25Å; K171-Y176 HydrophobicContact CB-CD1 4.13Å; K171-Y176 HydrophobicContact CB-CE1 3.9Å; K171-Y176 HydrophobicContact CG-CE1 4.5Å
177	T	91.1	Very high	89.3	Confident	16 Å²	16	79.5 Å²	79.5	10%	0.098	40%	0.399	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-116.8	161	176.3	59.5	0	0	0	0	110.5	Y89 S169 Q170 E172	Y89-T177 WeakPolarHBondContact OH-CB 3.01Å; S169-T177 WeakPolarHBondContact CA-O 3.23Å; S169-T177 WeakPolarHBondContact CB-O 3.32Å; S169-T177 PolarHBondContact OG-O 3.43Å; Q170-T177 PolarHBondContact N-O 3.04Å; Q170-T177 PolarHBondContact O-N 2.81Å; Q170-T177 PolarHBondContact O-OG1 3.37Å; E172-T177 HydrophobicContact CB-CG2 4.23Å; E172-T177 WeakPolarHBondContact OE2-CG2 3.31Å; E172-T177 PolarHBondContact OE2-OG1 3.01Å
178	C	93.6	Very high	89.1	Confident	11 Å²	11	83.5 Å²	83.5	7%	0.074	42%	0.418	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-124.5	100.9	169.3	173.1	0	0	0	0	106.8	W94 C101	W94-C178 HydrophobicContact CB-CB 4.41Å; W94-C178 HydrophobicContact CD2-CB 3.44Å; W94-C178 VanDerWaalsContact CD2-CB 3.44Å; W94-C178 HydrophobicContact CE3-CB 3.58Å; W94-C178 HydrophobicContact CG-CB 3.8Å; W94-C178 HydrophobicContact CH2-CB 4.38Å; W94-C178 HydrophobicContact CZ2-CB 4.34Å; W94-C178 HydrophobicContact CZ3-CB 4.04Å; C101-C178 VanDerWaalsContact CA-SG 3.59Å; C101-C178 HydrophobicContact CB-CB 3.93Å; C101-C178 WeakPolarHBondContact CB-SG 3.09Å; C101-C178 VanDerWaalsContact SG-CA 3.58Å; C101-C178 WeakPolarHBondContact SG-CB 3.38Å; C101-C178 CovalentContact SG-SG 2.03Å; C101-C178 PolarHBondContact SG-SG 3.27Å
179	S	89.7	Confident	89.2	Confident	33 Å²	33	82.7 Å²	82.7	23%	0.231	42%	0.419	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-145.2	162.5	-169.4	54.8	0	0	0	0	111.5	T167 R168 H181	T167-S179 WeakPolarHBondContact CA-O 3.35Å; R168-S179 PolarHBondContact N-O 3.22Å; R168-S179 PolarHBondContact O-N 3.33Å; R168-S179 VanDerWaalsContact O-N 3.12Å; S179-H181 PolarHBondContact O-CD2 2.8Å; S179-H181 VanDerWaalsContact O-CD2 3.31Å; S179-H181 PolarHBondContact OG-NE2 3.39Å
180	S	89.5	Confident	89.2	Confident	50 Å²	50	84.3 Å²	84.3	35%	0.35	42%	0.421	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-83.2	120.5	-178.9	-61.9	0	0	0	0	111.1	T167	T167-S180 PolarHBondContact OG1-OG 3.2Å; T167-S180 VanDerWaalsContact OG1-OG 3.13Å
181	H	89.3	Confident	89.3	Confident	55 Å²	55	82.2 Å²	82.2	26%	0.255	41%	0.411	S	S	.	.			trans	-112.7	108	176.6	-65.6	-72.8	0	0	0	110.6	F166 Q170 E172 S179	F166-H181 PolarHBondContact O-N 2.78Å; Q170-H181 WeakPolarHBondContact CG-NE2 3.41Å; Q170-H181 PolarHBondContact NE2-CE1 2.93Å; Q170-H181 PolarHBondContact NE2-NE2 3.07Å; E172-H181 IonicContact OE1-CE1 3.68Å; E172-H181 PolarHBondContact OE1-CE1 3.05Å; E172-H181 VanDerWaalsContact OE1-CE1 3.26Å; E172-H181 IonicContact OE1-NE2 2.76Å; S179-H181 PolarHBondContact O-CD2 2.8Å; S179-H181 VanDerWaalsContact O-CD2 3.31Å; S179-H181 PolarHBondContact OG-NE2 3.39Å
182	F	90.3	Very high	89.6	Confident	32 Å²	32	78 Å²	78	14%	0.14	39%	0.394	C	S	.	.			trans	-87.7	148	175.4	-55.9	-59.1	0	0	0	111.2	F166 Y184 Y187 W190 K191 H194	F166-F182 HydrophobicContact CB-CD1 3.85Å; F166-F182 HydrophobicContact CB-CE1 3.82Å; F166-F182 HydrophobicContact CD1-CD1 4.03Å; F166-F182 AromaticContact CD2-CD1 3.82Å; F166-F182 HydrophobicContact CD2-CD1 3.82Å; F166-F182 AromaticContact CD2-CE1 3.77Å; F166-F182 HydrophobicContact CD2-CE1 3.77Å; F166-F182 HydrophobicContact CE2-CD1 4.45Å; F166-F182 AromaticContact CG-CD1 3.62Å; F166-F182 HydrophobicContact CG-CD1 3.62Å; F166-F182 AromaticContact CG-CE1 3.85Å; F166-F182 HydrophobicContact CG-CE1 3.85Å; F182-Y184 PolarHBondContact O-N 3.15Å; F182-Y187 HydrophobicContact CB-CD2 3.92Å; F182-Y187 HydrophobicContact CB-CE2 4.39Å; F182-Y187 HydrophobicContact CD2-CD2 4.43Å; F182-Y187 HydrophobicContact CD2-CE2 4.16Å; F182-W190 HydrophobicContact CB-CB 3.94Å; F182-W190 HydrophobicContact CD1-CB 3.59Å; F182-W190 HydrophobicContact CE1-CB 4.29Å; F182-W190 HydrophobicContact CG-CB 3.83Å; F182-K191 HydrophobicContact CD2-CB 4.17Å; F182-K191 HydrophobicContact CE2-CB 4.19Å; F182-K191 HydrophobicContact CE2-CG 4.46Å; F182-H194 HydrophobicContact CE1-CB 4.38Å; F182-H194 HydrophobicContact CZ-CB 3.96Å
183	P	89.4	Confident	90.2	Very high	51 Å²	51	78.4 Å²	78.4	33%	0.331	40%	0.395	S	S	.	.			trans	-58.3	131.1	176.8	-21.3	31.3	0	0	0	111.6	F166 S185 Q186 Y187	F166-P183 HydrophobicContact CE1-CG 3.98Å; P183-S185 VanDerWaalsContact C-N 3.3Å; P183-S185 PolarHBondContact O-N 3.48Å; P183-Q186 CarbonylContact O-C 3.51Å; P183-Q186 PolarHBondContact O-N 3.02Å; P183-Q186 VanDerWaalsContact O-N 3.08Å; P183-Y187 VanDerWaalsContact O-CA 3.29Å; P183-Y187 WeakPolarHBondContact O-CA 3.49Å; P183-Y187 PolarHBondContact O-N 3.42Å
184	Y	88.4	Confident	90.7	Very high	226 Å²	226	76.4 Å²	76.4	89%	0.886	37%	0.367	S	S	*	.	G	3₁₀ helix	trans	-57	-41	-176	-176.5	-96.7	0	0	0	113	F182 Q186 Y187	F182-Y184 PolarHBondContact O-N 3.15Å; Y184-Q186 PolarHBondContact O-N 3.44Å; Y184-Q186 VanDerWaalsContact O-N 3.15Å; Y184-Y187 PolarHBondContact O-N 3.11Å
185	S	91.5	Very high	91.2	Very high	108 Å²	108	69.3 Å²	69.3	76%	0.755	33%	0.33	S	S	*	.	G	3₁₀ helix	trans	-61.4	-23.8	179.9	55.9	0	0	0	0	114.2	P183	P183-S185 VanDerWaalsContact C-N 3.3Å; P183-S185 PolarHBondContact O-N 3.48Å
186	Q	91.9	Very high	91.7	Very high	103 Å²	103	68.9 Å²	68.9	48%	0.481	33%	0.33	S	S	.	.	G	3₁₀ helix	trans	-133.6	27.3	-176.3	-66.2	179.8	-18.7	0	0	111.5	P183 Y184 Q188 F189 W190	P183-Q186 CarbonylContact O-C 3.51Å; P183-Q186 PolarHBondContact O-N 3.02Å; P183-Q186 VanDerWaalsContact O-N 3.08Å; Y184-Q186 PolarHBondContact O-N 3.44Å; Y184-Q186 VanDerWaalsContact O-N 3.15Å; Q186-Q188 PolarHBondContact O-N 2.82Å; Q186-F189 HydrophobicContact CB-CB 4.47Å; Q186-F189 PolarHBondContact O-N 3.24Å; Q186-F189 VanDerWaalsContact O-N 3.14Å; Q186-W190 VanDerWaalsContact O-CD1 3.31Å; Q186-W190 PolarHBondContact O-N 3.01Å; Q186-W190 VanDerWaalsContact O-N 3.09Å; Q186-W190 VanDerWaalsContact OE1-NE1 3.09Å
187	Y	90	Very high	92	Very high	108 Å²	108	64.6 Å²	64.6	42%	0.424	31%	0.314	S	S	.	.	H	α-helix	trans	-55.9	-49.9	-170	176.6	-94.6	0	0	0	112	F182 P183 Y184 F189 W190 K191	F182-Y187 HydrophobicContact CB-CD2 3.92Å; F182-Y187 HydrophobicContact CB-CE2 4.39Å; F182-Y187 HydrophobicContact CD2-CD2 4.43Å; F182-Y187 HydrophobicContact CD2-CE2 4.16Å; P183-Y187 VanDerWaalsContact O-CA 3.29Å; P183-Y187 WeakPolarHBondContact O-CA 3.49Å; P183-Y187 PolarHBondContact O-N 3.42Å; Y184-Y187 PolarHBondContact O-N 3.11Å; Y187-F189 VanDerWaalsContact C-N 3.33Å; Y187-F189 PolarHBondContact O-N 3.29Å; Y187-W190 PolarHBondContact O-N 3Å; Y187-K191 HydrophobicContact CE1-CD 3.84Å; Y187-K191 VanDerWaalsContact O-CB 3.26Å; Y187-K191 WeakPolarHBondContact O-CB 3.45Å; Y187-K191 PolarHBondContact O-N 3.25Å
188	Q	90.4	Very high	92.2	Very high	88 Å²	88	64 Å²	64	41%	0.411	31%	0.31	S	S	.	.	H	α-helix	trans	-64.2	-38	-178.8	-167.5	63.2	38.3	0	0	112.4	Q186 N192	Q186-Q188 PolarHBondContact O-N 2.82Å; Q188-N192 PolarHBondContact NE2-OD1 2.82Å; Q188-N192 VanDerWaalsContact O-CB 3.24Å; Q188-N192 WeakPolarHBondContact O-CB 3.25Å; Q188-N192 PolarHBondContact O-N 3.09Å; Q188-N192 PolarHBondContact O-ND2 3.11Å; Q188-N192 PolarHBondContact O-OD1 3.47Å
189	F	93.3	Very high	92.3	Very high	127 Å²	127	64.1 Å²	64.1	56%	0.557	31%	0.311	S	S	*	.	H	α-helix	trans	-62.6	-51.5	178.6	174.9	-93.8	0	0	0	111	Q186 Y187 N192 F193	Q186-F189 HydrophobicContact CB-CB 4.47Å; Q186-F189 PolarHBondContact O-N 3.24Å; Q186-F189 VanDerWaalsContact O-N 3.14Å; Y187-F189 VanDerWaalsContact C-N 3.33Å; Y187-F189 PolarHBondContact O-N 3.29Å; F189-N192 PolarHBondContact O-N 3.34Å; F189-F193 VanDerWaalsContact O-CB 3.28Å; F189-F193 WeakPolarHBondContact O-CB 3.2Å; F189-F193 PolarHBondContact O-N 2.91Å
190	W	93.4	Very high	92.7	Very high	60 Å²	60	66.8 Å²	66.8	23%	0.227	32%	0.321	C	S	.	.	H	α-helix	trans	-69	-37.2	-178.5	-73.2	109.2	0	0	0	112.8	F166 F182 Q186 Y187 F193 H194	F166-W190 HydrophobicContact CD2-CE3 4.4Å; F166-W190 HydrophobicContact CE1-CD2 4.32Å; F166-W190 AromaticContact CE2-CD2 3.73Å; F166-W190 HydrophobicContact CE2-CD2 3.73Å; F166-W190 AromaticContact CE2-CE3 3.28Å; F166-W190 HydrophobicContact CE2-CE3 3.28Å; F166-W190 HydrophobicContact CE2-CG 4.38Å; F166-W190 HydrophobicContact CE2-CH2 4.21Å; F166-W190 AromaticContact CE2-CZ3 3.56Å; F166-W190 HydrophobicContact CE2-CZ3 3.56Å; F166-W190 AromaticContact CZ-CD2 3.42Å; F166-W190 HydrophobicContact CZ-CD2 3.42Å; F166-W190 VanDerWaalsContact CZ-CD2 3.42Å; F166-W190 AromaticContact CZ-CE2 3.65Å; F166-W190 AromaticContact CZ-CE3 3.45Å; F166-W190 HydrophobicContact CZ-CE3 3.45Å; F166-W190 VanDerWaalsContact CZ-CE3 3.45Å; F166-W190 HydrophobicContact CZ-CG 4.02Å; F166-W190 AromaticContact CZ-CH2 3.9Å; F166-W190 HydrophobicContact CZ-CH2 3.9Å; F166-W190 AromaticContact CZ-CZ2 3.89Å; F166-W190 HydrophobicContact CZ-CZ2 3.89Å; F166-W190 AromaticContact CZ-CZ3 3.69Å; F166-W190 HydrophobicContact CZ-CZ3 3.69Å; F182-W190 HydrophobicContact CB-CB 3.94Å; F182-W190 HydrophobicContact CD1-CB 3.59Å; F182-W190 HydrophobicContact CE1-CB 4.29Å; F182-W190 HydrophobicContact CG-CB 3.83Å; Q186-W190 VanDerWaalsContact O-CD1 3.31Å; Q186-W190 PolarHBondContact O-N 3.01Å; Q186-W190 VanDerWaalsContact O-N 3.09Å; Q186-W190 VanDerWaalsContact OE1-NE1 3.09Å; Y187-W190 PolarHBondContact O-N 3Å; W190-F193 HydrophobicContact CE3-CD1 4.14Å; W190-F193 HydrophobicContact CZ3-CD1 4.15Å; W190-F193 HydrophobicContact CZ3-CE1 4.42Å; W190-F193 PolarHBondContact O-N 2.87Å; W190-H194 VanDerWaalsContact O-CB 3.28Å; W190-H194 WeakPolarHBondContact O-CB 3.41Å; W190-H194 PolarHBondContact O-N 3.37Å
191	K	91.4	Very high	93	Very high	36 Å²	36	66.3 Å²	66.3	16%	0.157	32%	0.315	C	S	.	.	H	α-helix	trans	-60	-50	172.5	-171.9	-176.1	177.6	-174.1	0	111	F182 Y187 H194 T195 T259	F182-K191 HydrophobicContact CD2-CB 4.17Å; F182-K191 HydrophobicContact CE2-CB 4.19Å; F182-K191 HydrophobicContact CE2-CG 4.46Å; Y187-K191 HydrophobicContact CE1-CD 3.84Å; Y187-K191 VanDerWaalsContact O-CB 3.26Å; Y187-K191 WeakPolarHBondContact O-CB 3.45Å; Y187-K191 PolarHBondContact O-N 3.25Å; K191-H194 PolarHBondContact O-N 3.41Å; K191-T195 PolarHBondContact O-N 2.94Å; K191-T195 VanDerWaalsContact O-N 3.09Å; K191-T195 PolarHBondContact O-OG1 3.22Å; K191-T259 HydrophobicContact CG-CG2 4.18Å
192	N	93.9	Very high	93.2	Very high	39 Å²	39	63.7 Å²	63.7	21%	0.209	30%	0.303	C	S	.	.	H	α-helix	trans	-62.5	-46.2	177.5	-71.7	-6.7	0	0	0	111.7	Q188 F189 H194 T195 L196 T259	Q188-N192 PolarHBondContact NE2-OD1 2.82Å; Q188-N192 VanDerWaalsContact O-CB 3.24Å; Q188-N192 WeakPolarHBondContact O-CB 3.25Å; Q188-N192 PolarHBondContact O-N 3.09Å; Q188-N192 PolarHBondContact O-ND2 3.11Å; Q188-N192 PolarHBondContact O-OD1 3.47Å; F189-N192 PolarHBondContact O-N 3.34Å; N192-H194 VanDerWaalsContact C-N 3.35Å; N192-H194 PolarHBondContact O-N 3.28Å; N192-T195 PolarHBondContact O-N 3.14Å; N192-L196 VanDerWaalsContact O-CB 3.3Å; N192-L196 WeakPolarHBondContact O-CB 3.43Å; N192-L196 VanDerWaalsContact O-CG 3.25Å; N192-L196 WeakPolarHBondContact O-CG 3.24Å; N192-L196 PolarHBondContact O-N 3.26Å; N192-T259 WeakPolarHBondContact OD1-CG2 3.47Å
193	F	95.1	Very high	93.4	Very high	91 Å²	91	63.6 Å²	63.6	40%	0.399	30%	0.304	S	S	.	.	H	α-helix	trans	-59.3	-45.8	178.8	177.3	-98.4	0	0	0	111.5	P162 F189 W190 K197	P162-F193 HydrophobicContact CB-CE1 4.49Å; P162-F193 HydrophobicContact CG-CE1 4.23Å; F189-F193 VanDerWaalsContact O-CB 3.28Å; F189-F193 WeakPolarHBondContact O-CB 3.2Å; F189-F193 PolarHBondContact O-N 2.91Å; W190-F193 HydrophobicContact CE3-CD1 4.14Å; W190-F193 HydrophobicContact CZ3-CD1 4.15Å; W190-F193 HydrophobicContact CZ3-CE1 4.42Å; W190-F193 PolarHBondContact O-N 2.87Å; F193-K197 WeakPolarHBondContact O-CB 3.2Å; F193-K197 PolarHBondContact O-N 3.46Å
194	H	93.4	Very high	93.8	Very high	25 Å²	25	64.8 Å²	64.8	12%	0.116	31%	0.309	C	S	.	.	H	α-helix	trans	-60	-49.6	178.4	-176.2	86	0	0	0	111.7	F109 F182 W190 K191 N192 K197 I198	F109-H194 AromaticContact CZ-CE1 3.68Å; F182-H194 HydrophobicContact CE1-CB 4.38Å; F182-H194 HydrophobicContact CZ-CB 3.96Å; W190-H194 VanDerWaalsContact O-CB 3.28Å; W190-H194 WeakPolarHBondContact O-CB 3.41Å; W190-H194 PolarHBondContact O-N 3.37Å; K191-H194 PolarHBondContact O-N 3.41Å; N192-H194 VanDerWaalsContact C-N 3.35Å; N192-H194 PolarHBondContact O-N 3.28Å; H194-K197 PolarHBondContact O-N 3.26Å; H194-I198 VanDerWaalsContact NE2-CD1 3.27Å; H194-I198 WeakPolarHBondContact NE2-CD1 3.39Å; H194-I198 WeakPolarHBondContact O-CG1 3.37Å; H194-I198 PolarHBondContact O-N 3.24Å; H194-I198 VanDerWaalsContact O-N 3.13Å
195	T	94.2	Very high	94.2	Very high	4 Å²	4	57 Å²	57	3%	0.025	28%	0.283	C	S	.	.	H	α-helix	trans	-63.7	-50.2	179.1	-65.4	0	0	0	0	112.1	K191 N192 K197 I198 V199 L255 L256 T259	K191-T195 PolarHBondContact O-N 2.94Å; K191-T195 VanDerWaalsContact O-N 3.09Å; K191-T195 PolarHBondContact O-OG1 3.22Å; N192-T195 PolarHBondContact O-N 3.14Å; T195-K197 VanDerWaalsContact C-N 3.3Å; T195-K197 PolarHBondContact O-N 3.42Å; T195-I198 PolarHBondContact O-N 3.31Å; T195-V199 HydrophobicContact CG2-CG2 4.29Å; T195-V199 WeakPolarHBondContact O-CG2 3.4Å; T195-V199 PolarHBondContact O-N 3.41Å; T195-L255 HydrophobicContact CG2-CD2 4.38Å; T195-L255 HydrophobicContact CG2-CG 4.02Å; T195-L256 HydrophobicContact CG2-CD1 4.35Å; T195-T259 WeakPolarHBondContact CB-OG1 3.46Å; T195-T259 HydrophobicContact CG2-CG2 4.17Å; T195-T259 WeakPolarHBondContact CG2-OG1 3.41Å; T195-T259 PolarHBondContact OG1-OG1 2.82Å
196	L	96.1	Very high	94.3	Very high	72 Å²	72	51.9 Å²	51.9	38%	0.377	25%	0.247	S	C	.	.	H	α-helix	trans	-61.7	-40	-180	-70.8	175.1	0	0	0	111.3	N192 I198 V199 I200 F260	N192-L196 VanDerWaalsContact O-CB 3.3Å; N192-L196 WeakPolarHBondContact O-CB 3.43Å; N192-L196 VanDerWaalsContact O-CG 3.25Å; N192-L196 WeakPolarHBondContact O-CG 3.24Å; N192-L196 PolarHBondContact O-N 3.26Å; L196-I198 PolarHBondContact O-N 3.48Å; L196-V199 PolarHBondContact O-N 3.16Å; L196-I200 HydrophobicContact CB-CD1 4.26Å; L196-I200 WeakPolarHBondContact O-CB 3.31Å; L196-I200 WeakPolarHBondContact O-CD1 3.48Å; L196-I200 WeakPolarHBondContact O-CG1 3.49Å; L196-I200 PolarHBondContact O-N 3.13Å; L196-F260 HydrophobicContact CD2-CE2 4.35Å; L196-F260 HydrophobicContact CD2-CZ 4.42Å
197	K	96.2	Very high	94.4	Very high	22 Å²	22	50.9 Å²	50.9	10%	0.096	24%	0.244	C	C	.	.	H	α-helix	trans	-57.6	-49.4	174.4	-179.5	-155.5	69.3	165.9	0	111.4	F113 A159 F193 H194 T195 L201	F113-K197 HydrophobicContact CZ-CD 4.38Å; A159-K197 PolarHBondContact O-NZ 3.4Å; F193-K197 WeakPolarHBondContact O-CB 3.2Å; F193-K197 PolarHBondContact O-N 3.46Å; H194-K197 PolarHBondContact O-N 3.26Å; T195-K197 VanDerWaalsContact C-N 3.3Å; T195-K197 PolarHBondContact O-N 3.42Å; K197-L201 HydrophobicContact CG-CD1 3.88Å; K197-L201 WeakPolarHBondContact O-CB 3.44Å; K197-L201 WeakPolarHBondContact O-CG 3.37Å; K197-L201 PolarHBondContact O-N 2.96Å
198	I	95.4	Very high	94.7	Very high	2 Å²	2	50.5 Å²	50.5	1%	0.01	25%	0.249	C	C	.	.	H	α-helix	trans	-62.7	-47.9	179.8	-69.8	171.2	0	0	0	110.5	F109 F112 F113 H194 T195 L196 G202 N252 L255	F109-I198 HydrophobicContact CE1-CD1 3.98Å; F112-I198 HydrophobicContact CE1-CG2 4.26Å; F112-I198 HydrophobicContact CZ-CG2 4.31Å; F113-I198 HydrophobicContact CZ-CG1 4.21Å; H194-I198 VanDerWaalsContact NE2-CD1 3.27Å; H194-I198 WeakPolarHBondContact NE2-CD1 3.39Å; H194-I198 WeakPolarHBondContact O-CG1 3.37Å; H194-I198 PolarHBondContact O-N 3.24Å; H194-I198 VanDerWaalsContact O-N 3.13Å; T195-I198 PolarHBondContact O-N 3.31Å; L196-I198 PolarHBondContact O-N 3.48Å; I198-G202 VanDerWaalsContact O-CA 3.28Å; I198-G202 WeakPolarHBondContact O-CA 3.31Å; I198-G202 PolarHBondContact O-N 3.46Å; I198-N252 WeakPolarHBondContact CG2-OD1 3.3Å; I198-N252 PolarHBondContact O-OD1 3.26Å; I198-L255 HydrophobicContact CB-CD2 4.11Å; I198-L255 HydrophobicContact CD1-CD2 4.05Å; I198-L255 HydrophobicContact CG2-CD2 3.86Å
199	V	96.1	Very high	94.9	Very high	15 Å²	15	47.2 Å²	47.2	9%	0.091	24%	0.235	C	C	.	.	H	α-helix	trans	-66.5	-43.1	-178.5	173.5	0	0	0	0	111.8	T195 L196 L203 V204 N252 L256	T195-V199 HydrophobicContact CG2-CG2 4.29Å; T195-V199 WeakPolarHBondContact O-CG2 3.4Å; T195-V199 PolarHBondContact O-N 3.41Å; L196-V199 PolarHBondContact O-N 3.16Å; V199-L203 WeakPolarHBondContact O-CA 3.4Å; V199-L203 VanDerWaalsContact O-CB 3.28Å; V199-L203 WeakPolarHBondContact O-CB 3.28Å; V199-L203 PolarHBondContact O-N 2.83Å; V199-V204 HydrophobicContact CG1-CG2 4.26Å; V199-V204 PolarHBondContact O-N 2.96Å; V199-N252 HydrophobicContact CG2-CB 4.4Å; V199-L256 HydrophobicContact CG2-CB 4.48Å; V199-L256 HydrophobicContact CG2-CD1 4.44Å
200	I	97.2	Very high	94.8	Very high	88 Å²	88	42.4 Å²	42.4	45%	0.451	22%	0.215	S	C	.	.	I	π-helix	trans	-65.4	-50.3	-179.5	-69.8	166.6	0	0	0	110.1	L196 V204 L205	L196-I200 HydrophobicContact CB-CD1 4.26Å; L196-I200 WeakPolarHBondContact O-CB 3.31Å; L196-I200 WeakPolarHBondContact O-CD1 3.48Å; L196-I200 WeakPolarHBondContact O-CG1 3.49Å; L196-I200 PolarHBondContact O-N 3.13Å; I200-V204 PolarHBondContact O-N 3.33Å; I200-L205 VanDerWaalsContact O-CB 3.23Å; I200-L205 WeakPolarHBondContact O-CB 3.34Å; I200-L205 PolarHBondContact O-N 2.95Å
201	L	96.8	Very high	94.8	Very high	41 Å²	41	43.5 Å²	43.5	22%	0.215	23%	0.228	C	C	.	.	I	π-helix	trans	-77.7	-33.6	-175.4	-61.7	178.2	0	0	0	112.9	F113 F117 A159 K197 L205 P206	F113-L201 HydrophobicContact CD1-CB 4.26Å; F113-L201 HydrophobicContact CD1-CD1 4.3Å; F113-L201 HydrophobicContact CE1-CB 4.02Å; F113-L201 HydrophobicContact CE1-CD1 4.01Å; F117-L201 HydrophobicContact CE1-CB 4.38Å; F117-L201 HydrophobicContact CE1-CD2 4.45Å; F117-L201 HydrophobicContact CZ-CD1 4.32Å; F117-L201 HydrophobicContact CZ-CD2 4.46Å; A159-L201 HydrophobicContact CB-CD1 4.31Å; K197-L201 HydrophobicContact CG-CD1 3.88Å; K197-L201 WeakPolarHBondContact O-CB 3.44Å; K197-L201 WeakPolarHBondContact O-CG 3.37Å; K197-L201 PolarHBondContact O-N 2.96Å; L201-L205 HydrophobicContact CD2-CD2 4.27Å; L201-P206 WeakPolarHBondContact O-CD 3.46Å
202	G	93.4	Very high	94.9	Very high	0 Å²	0	46.4 Å²	46.4	0%	0	24%	0.244	C	C	.	.	I	π-helix	trans	-93.2	-18.8	-175.8	0	0	0	0	0	115	I198 P206 Y244	I198-G202 VanDerWaalsContact O-CA 3.28Å; I198-G202 WeakPolarHBondContact O-CA 3.31Å; I198-G202 PolarHBondContact O-N 3.46Å; G202-P206 WeakPolarHBondContact O-CG 3.29Å; G202-Y244 VanDerWaalsContact O-CE1 3.3Å; G202-Y244 WeakPolarHBondContact O-CE1 3.21Å; G202-Y244 PolarHBondContact O-OH 3.06Å; G202-Y244 VanDerWaalsContact O-OH 3.07Å
203	L	94.9	Very high	94.8	Very high	30 Å²	30	45 Å²	45	16%	0.157	24%	0.237	C	C	.	.	I	π-helix	trans	-128.7	-56.3	-178.6	-176.9	63.6	0	0	0	112.7	V199 P206 L207 F245 A249 N252 I253	V199-L203 WeakPolarHBondContact O-CA 3.4Å; V199-L203 VanDerWaalsContact O-CB 3.28Å; V199-L203 WeakPolarHBondContact O-CB 3.28Å; V199-L203 PolarHBondContact O-N 2.83Å; L203-P206 WeakPolarHBondContact O-CD 3.31Å; L203-P206 WeakPolarHBondContact O-CG 3.35Å; L203-L207 WeakPolarHBondContact O-CB 3.34Å; L203-L207 PolarHBondContact O-N 3.17Å; L203-L207 VanDerWaalsContact O-N 3.1Å; L203-F245 HydrophobicContact CD1-CD1 3.78Å; L203-F245 HydrophobicContact CD1-CE1 3.87Å; L203-A249 HydrophobicContact CD1-CB 3.76Å; L203-N252 HydrophobicContact CB-CB 4.21Å; L203-N252 HydrophobicContact CD2-CB 3.97Å; L203-I253 HydrophobicContact CD2-CG1 4.48Å
204	V	96.7	Very high	94.4	Very high	75 Å²	75	42 Å²	42	46%	0.455	22%	0.224	S	C	.	.	I	π-helix	trans	-68	-49.2	-172	-179	0	0	0	0	111.7	V199 I200 L207 L208	V199-V204 HydrophobicContact CG1-CG2 4.26Å; V199-V204 PolarHBondContact O-N 2.96Å; I200-V204 PolarHBondContact O-N 3.33Å; V204-L207 PolarHBondContact O-N 3.48Å; V204-L208 WeakPolarHBondContact O-CB 3.28Å; V204-L208 PolarHBondContact O-N 2.89Å
205	L	96.2	Very high	94.2	Very high	63 Å²	63	44.3 Å²	44.3	33%	0.33	24%	0.243	S	C	.	.	H	α-helix	trans	-59.5	-53.8	179.3	178.7	66.4	0	0	0	112.8	F117 I120 I200 L201 L207 L208 V209	F117-L205 HydrophobicContact CE1-CD2 4.34Å; I120-L205 HydrophobicContact CD1-CD2 3.98Å; I120-L205 HydrophobicContact CD1-CG 3.98Å; I200-L205 VanDerWaalsContact O-CB 3.23Å; I200-L205 WeakPolarHBondContact O-CB 3.34Å; I200-L205 PolarHBondContact O-N 2.95Å; L201-L205 HydrophobicContact CD2-CD2 4.27Å; L205-L207 VanDerWaalsContact C-N 3.27Å; L205-L207 PolarHBondContact O-N 3.39Å; L205-L208 PolarHBondContact O-N 3.46Å; L205-V209 WeakPolarHBondContact O-CG2 3.46Å; L205-V209 PolarHBondContact O-N 2.98Å
206	P	94.1	Very high	93.9	Very high	0 Å²	0	44.9 Å²	44.9	0%	0	25%	0.249	C	C	.	.	H	α-helix	trans	-63.8	-33	178.3	23.8	-33.6	0	0	0	112.4	I116 I120 L201 G202 L203 V209 M210 M241 F245	I116-P206 HydrophobicContact CD1-CB 3.55Å; I116-P206 HydrophobicContact CD1-CG 3.81Å; I116-P206 HydrophobicContact CG1-CB 3.97Å; I116-P206 HydrophobicContact CG1-CG 3.83Å; I120-P206 HydrophobicContact CD1-CB 4Å; I120-P206 HydrophobicContact CG1-CB 3.98Å; L201-P206 WeakPolarHBondContact O-CD 3.46Å; G202-P206 WeakPolarHBondContact O-CG 3.29Å; L203-P206 WeakPolarHBondContact O-CD 3.31Å; L203-P206 WeakPolarHBondContact O-CG 3.35Å; P206-V209 PolarHBondContact O-N 2.95Å; P206-M210 VanDerWaalsContact O-CB 3.26Å; P206-M210 WeakPolarHBondContact O-CB 3.39Å; P206-M210 PolarHBondContact O-N 3.44Å; P206-M241 HydrophobicContact CB-SD 4.31Å; P206-F245 HydrophobicContact CB-CE1 4.27Å; P206-F245 HydrophobicContact CB-CZ 3.87Å; P206-F245 HydrophobicContact CG-CE1 4.02Å; P206-F245 HydrophobicContact CG-CZ 4.12Å
207	L	94.6	Very high	93.4	Very high	82 Å²	82	41.5 Å²	41.5	43%	0.429	23%	0.231	S	C	.	.	H	α-helix	trans	-67	-43.4	177	-175	68.4	0	0	0	111.2	L203 V204 L205 M210 V211 F245	L203-L207 WeakPolarHBondContact O-CB 3.34Å; L203-L207 PolarHBondContact O-N 3.17Å; L203-L207 VanDerWaalsContact O-N 3.1Å; V204-L207 PolarHBondContact O-N 3.48Å; L205-L207 VanDerWaalsContact C-N 3.27Å; L205-L207 PolarHBondContact O-N 3.39Å; L207-M210 WeakPolarHBondContact O-CB 3.17Å; L207-M210 PolarHBondContact O-N 3.36Å; L207-V211 WeakPolarHBondContact O-CG2 3.43Å; L207-V211 PolarHBondContact O-N 2.79Å; L207-F245 HydrophobicContact CB-CE1 4.33Å; L207-F245 HydrophobicContact CB-CZ 4.05Å; L207-F245 HydrophobicContact CD1-CE2 4.48Å; L207-F245 HydrophobicContact CD1-CZ 4.31Å
208	L	96.1	Very high	92.9	Very high	100 Å²	100	45.4 Å²	45.4	52%	0.524	25%	0.253	S	S	.	.	H	α-helix	trans	-60.1	-48.2	175.2	179.6	63.8	0	0	0	111.2	V204 L205 M210 V211 I212	V204-L208 WeakPolarHBondContact O-CB 3.28Å; V204-L208 PolarHBondContact O-N 2.89Å; L205-L208 PolarHBondContact O-N 3.46Å; L208-M210 VanDerWaalsContact C-N 3.28Å; L208-M210 PolarHBondContact O-N 3.44Å; L208-V211 PolarHBondContact O-N 3.34Å; L208-I212 HydrophobicContact CD1-CD1 3.8Å; L208-I212 HydrophobicContact CD1-CG1 4.34Å; L208-I212 HydrophobicContact CG-CD1 3.88Å; L208-I212 WeakPolarHBondContact O-CG1 3.47Å; L208-I212 PolarHBondContact O-N 3.16Å
209	V	94.7	Very high	92.5	Very high	20 Å²	20	53 Å²	53	12%	0.121	29%	0.286	C	S	.	.	H	α-helix	trans	-58.6	-43.7	175.9	171.6	0	0	0	0	110.4	I120 T123 I124 L205 P206 I212 C213	I120-V209 HydrophobicContact CG2-CG1 4.22Å; I120-V209 HydrophobicContact CG2-CG2 4.05Å; T123-V209 HydrophobicContact CG2-CG1 3.98Å; I124-V209 HydrophobicContact CG1-CG1 4.13Å; L205-V209 WeakPolarHBondContact O-CG2 3.46Å; L205-V209 PolarHBondContact O-N 2.98Å; P206-V209 PolarHBondContact O-N 2.95Å; V209-I212 PolarHBondContact O-N 3.44Å; V209-C213 WeakPolarHBondContact O-CB 3.22Å; V209-C213 PolarHBondContact O-N 2.94Å; V209-C213 PolarHBondContact O-SG 2.89Å; V209-C213 VanDerWaalsContact O-SG 3.4Å
210	M	90.6	Very high	91.8	Very high	26 Å²	26	53.8 Å²	53.8	13%	0.128	29%	0.291	C	S	.	.	H	α-helix	trans	-59.4	-51.5	178.4	-174.8	-170.3	176.3	0	0	111.2	P206 L207 L208 I212 C213 Y214 F238 M241 I242 F245	P206-M210 VanDerWaalsContact O-CB 3.26Å; P206-M210 WeakPolarHBondContact O-CB 3.39Å; P206-M210 PolarHBondContact O-N 3.44Å; L207-M210 WeakPolarHBondContact O-CB 3.17Å; L207-M210 PolarHBondContact O-N 3.36Å; L208-M210 VanDerWaalsContact C-N 3.28Å; L208-M210 PolarHBondContact O-N 3.44Å; M210-I212 PolarHBondContact O-N 2.87Å; M210-C213 PolarHBondContact O-N 2.71Å; M210-Y214 HydrophobicContact CB-CD2 4.32Å; M210-Y214 HydrophobicContact CG-CD2 3.54Å; M210-Y214 HydrophobicContact CG-CE2 3.96Å; M210-Y214 VanDerWaalsContact O-CB 3.31Å; M210-Y214 WeakPolarHBondContact O-CB 3.43Å; M210-Y214 VanDerWaalsContact O-CD2 3.3Å; M210-Y214 WeakPolarHBondContact O-CD2 3.43Å; M210-Y214 PolarHBondContact O-N 3.07Å; M210-F238 HydrophobicContact CE-CD2 4.15Å; M210-F238 HydrophobicContact CE-CE2 3.49Å; M210-F238 VanDerWaalsContact CE-CE2 3.49Å; M210-F238 HydrophobicContact CE-CZ 4.22Å; M210-M241 HydrophobicContact CB-CG 4.43Å; M210-M241 HydrophobicContact CG-CG 4.16Å; M210-M241 HydrophobicContact SD-CG 3.98Å; M210-I242 HydrophobicContact CE-CD1 3.3Å; M210-I242 HydrophobicContact CE-CG1 4.22Å; M210-I242 HydrophobicContact SD-CD1 4.42Å; M210-F245 HydrophobicContact SD-CD2 4.09Å; M210-F245 HydrophobicContact SD-CE2 3.57Å; M210-F245 VanDerWaalsContact SD-CE2 3.57Å
211	V	92.8	Very high	90.9	Very high	83 Å²	83	50.7 Å²	50.7	50%	0.503	28%	0.275	S	S	.	.	H	α-helix	trans	-59.3	-46.2	-179.3	171.1	0	0	0	0	111.3	L207 L208 S215	L207-V211 WeakPolarHBondContact O-CG2 3.43Å; L207-V211 PolarHBondContact O-N 2.79Å; L208-V211 PolarHBondContact O-N 3.34Å; V211-S215 WeakPolarHBondContact O-CB 3.44Å; V211-S215 PolarHBondContact O-N 3.13Å; V211-S215 PolarHBondContact O-OG 3.46Å
212	I	93.8	Very high	90	Very high	97 Å²	97	55.3 Å²	55.3	50%	0.497	30%	0.299	S	S	.	.	H	α-helix	trans	-66.8	-52.6	-178.7	-65	169	0	0	0	110.6	L208 V209 M210 G216	L208-I212 HydrophobicContact CD1-CD1 3.8Å; L208-I212 HydrophobicContact CD1-CG1 4.34Å; L208-I212 HydrophobicContact CG-CD1 3.88Å; L208-I212 WeakPolarHBondContact O-CG1 3.47Å; L208-I212 PolarHBondContact O-N 3.16Å; V209-I212 PolarHBondContact O-N 3.44Å; M210-I212 PolarHBondContact O-N 2.87Å; I212-G216 PolarHBondContact O-N 2.85Å
213	C	91.9	Very high	89.3	Confident	9 Å²	9	66 Å²	66	6%	0.061	34%	0.339	C	S	.	.	H	α-helix	trans	-67.5	-46.1	-174.1	-71.7	0	0	0	0	112	T123 Y127 V209 M210 G216 I217	T123-C213 HydrophobicContact CG2-CB 3.74Å; Y127-C213 VanDerWaalsContact CD2-CA 3.46Å; Y127-C213 HydrophobicContact CD2-CB 3.84Å; Y127-C213 VanDerWaalsContact CD2-O 3.29Å; Y127-C213 WeakPolarHBondContact CD2-O 3.43Å; Y127-C213 HydrophobicContact CG-CB 4.07Å; V209-C213 WeakPolarHBondContact O-CB 3.22Å; V209-C213 PolarHBondContact O-N 2.94Å; V209-C213 PolarHBondContact O-SG 2.89Å; V209-C213 VanDerWaalsContact O-SG 3.4Å; M210-C213 PolarHBondContact O-N 2.71Å; C213-G216 PolarHBondContact O-N 2.9Å; C213-I217 WeakPolarHBondContact O-CB 3.1Å; C213-I217 WeakPolarHBondContact O-CD1 3.27Å; C213-I217 VanDerWaalsContact O-CG1 3.24Å; C213-I217 WeakPolarHBondContact O-CG1 3.23Å; C213-I217 PolarHBondContact O-N 3.29Å
214	Y	87.8	Confident	88	Confident	28 Å²	28	67.6 Å²	67.6	11%	0.11	35%	0.352	C	S	.	.	H	α-helix	trans	-72.7	-31.6	-177.1	-76.2	-78.1	0	0	0	112.9	T123 M210 I217 L218 V234 I237 F238	T123-Y214 HydrophobicContact CG2-CD2 4.47Å; T123-Y214 HydrophobicContact CG2-CE2 3.85Å; M210-Y214 HydrophobicContact CB-CD2 4.32Å; M210-Y214 HydrophobicContact CG-CD2 3.54Å; M210-Y214 HydrophobicContact CG-CE2 3.96Å; M210-Y214 VanDerWaalsContact O-CB 3.31Å; M210-Y214 WeakPolarHBondContact O-CB 3.43Å; M210-Y214 VanDerWaalsContact O-CD2 3.3Å; M210-Y214 WeakPolarHBondContact O-CD2 3.43Å; M210-Y214 PolarHBondContact O-N 3.07Å; Y214-I217 HydrophobicContact CD1-CD1 4.24Å; Y214-I217 HydrophobicContact CE1-CD1 4.34Å; Y214-I217 PolarHBondContact O-N 3.46Å; Y214-L218 VanDerWaalsContact O-CB 3.23Å; Y214-L218 WeakPolarHBondContact O-CB 3.26Å; Y214-L218 PolarHBondContact O-N 3.33Å; Y214-V234 HydrophobicContact CE1-CG1 4.11Å; Y214-I237 VanDerWaalsContact OH-C 3.23Å; Y214-F238 AromaticContact CD1-CD2 3.71Å; Y214-F238 HydrophobicContact CD1-CD2 3.71Å; Y214-F238 HydrophobicContact CD1-CE2 4.4Å; Y214-F238 HydrophobicContact CD2-CD2 4.29Å; Y214-F238 HydrophobicContact CE1-CB 3.68Å; Y214-F238 AromaticContact CE1-CD2 3.49Å; Y214-F238 HydrophobicContact CE1-CD2 3.49Å; Y214-F238 VanDerWaalsContact CE1-CD2 3.49Å; Y214-F238 HydrophobicContact CE1-CG 4.03Å; Y214-F238 HydrophobicContact CE2-CD2 4.1Å; Y214-F238 HydrophobicContact CG-CD2 4.12Å; Y214-F238 AromaticContact CZ-CD2 3.71Å; Y214-F238 WeakPolarHBondContact OH-CA 3.28Å; Y214-F238 PolarHBondContact OH-N 3.35Å
215	S	88.8	Confident	86.4	Confident	74 Å²	74	74.8 Å²	74.8	52%	0.517	37%	0.371	S	S	.	.	H	α-helix	trans	-58.4	-47.5	170.1	-65.9	0	0	0	0	111.7	V211 L218 K219	V211-S215 WeakPolarHBondContact O-CB 3.44Å; V211-S215 PolarHBondContact O-N 3.13Å; V211-S215 PolarHBondContact O-OG 3.46Å; S215-L218 PolarHBondContact O-N 3.37Å; S215-K219 WeakPolarHBondContact O-CB 3.34Å; S215-K219 PolarHBondContact O-N 3.19Å
216	G	87.8	Confident	84.5	Confident	15 Å²	15	78.5 Å²	78.5	16%	0.155	39%	0.391	C	S	.	.	H	α-helix	trans	-69	-38.2	178.2	0	0	0	0	0	113.6	I212 C213 T220	I212-G216 PolarHBondContact O-N 2.85Å; C213-G216 PolarHBondContact O-N 2.9Å; G216-T220 WeakPolarHBondContact O-CB 3.46Å; G216-T220 PolarHBondContact O-N 2.97Å; G216-T220 VanDerWaalsContact O-N 3.11Å; G216-T220 PolarHBondContact O-OG1 3.23Å
217	I	86.2	Confident	83.1	Confident	2 Å²	2	84.1 Å²	84.1	1%	0.01	42%	0.418	C	S	.	.	H	α-helix	trans	-61.7	-48.5	173.9	-71.5	164.1	0	0	0	110.1	Y127 V130 V131 C213 Y214 K219 T220 L221 V234	Y127-I217 HydrophobicContact CD2-CG1 4.12Å; V130-I217 HydrophobicContact CB-CG1 4.35Å; V130-I217 HydrophobicContact CG1-CG1 4.38Å; V130-I217 HydrophobicContact CG1-CG2 4.29Å; V131-I217 HydrophobicContact CG2-CG1 4.26Å; C213-I217 WeakPolarHBondContact O-CB 3.1Å; C213-I217 WeakPolarHBondContact O-CD1 3.27Å; C213-I217 VanDerWaalsContact O-CG1 3.24Å; C213-I217 WeakPolarHBondContact O-CG1 3.23Å; C213-I217 PolarHBondContact O-N 3.29Å; Y214-I217 HydrophobicContact CD1-CD1 4.24Å; Y214-I217 HydrophobicContact CE1-CD1 4.34Å; Y214-I217 PolarHBondContact O-N 3.46Å; I217-K219 PolarHBondContact O-N 2.93Å; I217-T220 PolarHBondContact O-N 2.92Å; I217-L221 HydrophobicContact CG2-CD1 3.54Å; I217-L221 HydrophobicContact CG2-CG 4.1Å; I217-L221 WeakPolarHBondContact O-CB 3.31Å; I217-L221 VanDerWaalsContact O-CG 3.28Å; I217-L221 WeakPolarHBondContact O-CG 3.47Å; I217-L221 PolarHBondContact O-N 3.38Å; I217-V234 HydrophobicContact CG2-CG1 3.75Å; I217-V234 HydrophobicContact CG2-CG2 3.94Å
218	L	85.4	Confident	81.6	Confident	103 Å²	103	88.4 Å²	88.4	54%	0.539	43%	0.433	S	S	.	.	H	α-helix	trans	-61.9	-46.5	-178.7	-174.8	61.7	0	0	0	111.1	Y214 S215 T220 L221 L222	Y214-L218 VanDerWaalsContact O-CB 3.23Å; Y214-L218 WeakPolarHBondContact O-CB 3.26Å; Y214-L218 PolarHBondContact O-N 3.33Å; S215-L218 PolarHBondContact O-N 3.37Å; L218-T220 VanDerWaalsContact C-N 3.25Å; L218-T220 PolarHBondContact O-N 2.98Å; L218-L221 PolarHBondContact O-N 3.46Å; L218-L222 HydrophobicContact CD1-CD1 4.4Å; L218-L222 HydrophobicContact CD1-CG 4.32Å; L218-L222 HydrophobicContact CG-CD1 4.08Å; L218-L222 HydrophobicContact CG-CG 4.44Å; L218-L222 WeakPolarHBondContact O-CB 3.31Å; L218-L222 VanDerWaalsContact O-CG 3.28Å; L218-L222 WeakPolarHBondContact O-CG 3.47Å; L218-L222 PolarHBondContact O-N 3.1Å
219	K	86.6	Confident	79.9	Confident	163 Å²	163	90.9 Å²	90.9	71%	0.709	44%	0.439	S	S	*	.	H	α-helix	trans	-55.1	-41.7	175	-173.2	176.1	-178.5	176.5	0	112.2	S215 I217 R223	S215-K219 WeakPolarHBondContact O-CB 3.34Å; S215-K219 PolarHBondContact O-N 3.19Å; I217-K219 PolarHBondContact O-N 2.93Å; K219-R223 PolarHBondContact O-N 2.88Å
220	T	81.6	Confident	78.6	Confident	31 Å²	31	92.5 Å²	92.5	19%	0.19	44%	0.443	C	S	.	.	H	α-helix	trans	-75.8	-32.8	-179.4	-52.9	0	0	0	0	112.7	V130 G216 I217 L218 C224 R230	V130-T220 HydrophobicContact CG1-CG2 4.21Å; G216-T220 WeakPolarHBondContact O-CB 3.46Å; G216-T220 PolarHBondContact O-N 2.97Å; G216-T220 VanDerWaalsContact O-N 3.11Å; G216-T220 PolarHBondContact O-OG1 3.23Å; I217-T220 PolarHBondContact O-N 2.92Å; L218-T220 VanDerWaalsContact C-N 3.25Å; L218-T220 PolarHBondContact O-N 2.98Å; T220-C224 PolarHBondContact O-N 3.47Å; T220-R230 PolarHBondContact O-NH2 3.46Å
221	L	77.6	Confident	77.6	Confident	22 Å²	22	95 Å²	95	12%	0.115	45%	0.454	C	S	.	.	H	α-helix	trans	-71.3	-39.5	175.4	-71	171.8	0	0	0	111.7	I217 L218 R223 C224 R230 V234	I217-L221 HydrophobicContact CG2-CD1 3.54Å; I217-L221 HydrophobicContact CG2-CG 4.1Å; I217-L221 WeakPolarHBondContact O-CB 3.31Å; I217-L221 VanDerWaalsContact O-CG 3.28Å; I217-L221 WeakPolarHBondContact O-CG 3.47Å; I217-L221 PolarHBondContact O-N 3.38Å; L218-L221 PolarHBondContact O-N 3.46Å; L221-R223 VanDerWaalsContact C-N 3.29Å; L221-R223 PolarHBondContact O-N 3.02Å; L221-C224 CarbonylContact O-C 3.08Å; L221-C224 PolarHBondContact O-N 3.29Å; L221-R230 HydrophobicContact CD2-CG 4.15Å; L221-R230 VanDerWaalsContact CD2-NE 3.32Å; L221-V234 HydrophobicContact CD1-CG1 4.41Å
222	L	79.1	Confident	76.5	Confident	138 Å²	138	97 Å²	97	72%	0.723	45%	0.453	S	S	*	.	H	α-helix	trans	-64	-35.2	175	-69.2	171.9	0	0	0	111.9	L218	L218-L222 HydrophobicContact CD1-CD1 4.4Å; L218-L222 HydrophobicContact CD1-CG 4.32Å; L218-L222 HydrophobicContact CG-CD1 4.08Å; L218-L222 HydrophobicContact CG-CG 4.44Å; L218-L222 WeakPolarHBondContact O-CB 3.31Å; L218-L222 VanDerWaalsContact O-CG 3.28Å; L218-L222 WeakPolarHBondContact O-CG 3.47Å; L218-L222 PolarHBondContact O-N 3.1Å
223	R	78.8	Confident	75.3	Confident	224 Å²	224	94.1 Å²	94.1	85%	0.845	44%	0.444	S	S	*	.	H	α-helix	trans	-76.6	-29.3	179	-166.2	173.7	-178.3	-177.4	0.6	114	K219 L221	K219-R223 PolarHBondContact O-N 2.88Å; L221-R223 VanDerWaalsContact C-N 3.29Å; L221-R223 PolarHBondContact O-N 3.02Å
224	C	66.4	Low	74.6	Confident	64 Å²	64	94.4 Å²	94.4	43%	0.432	45%	0.445	S	S	.	.			trans	-125.4	93.5	-176.5	-56.4	0	0	0	0	110.7	T220 L221 N226 R230	T220-C224 PolarHBondContact O-N 3.47Å; L221-C224 CarbonylContact O-C 3.08Å; L221-C224 PolarHBondContact O-N 3.29Å; C224-N226 PolarHBondContact O-N 2.99Å; C224-R230 PolarHBondContact O-NH2 2.89Å
225	R	63.2	Low	74.3	Confident	226 Å²	226	99 Å²	99	85%	0.853	46%	0.462	S	S	*	.	T	Hydrogen-bonded Turn	trans	-76.1	-8.7	-169	-161.4	160.8	91.3	163.6	3.7	115.8
226	N	56.4	Low	74	Confident	142 Å²	142	97 Å²	97	76%	0.759	45%	0.445	S	S	*	.	T	Hydrogen-bonded Turn	trans	-102.4	5	-158	-71.9	-6.7	0	0	0	117.6	C224	C224-N226 PolarHBondContact O-N 2.99Å
227	E	65.2	Low	73.7	Confident	117 Å²	117	96.6 Å²	96.6	55%	0.547	44%	0.439	S	S	.	.			trans	-117.2	82.4	-172.5	-74.2	-65.3	162.4	0	0	114.4	K229 R230 H231	E227-K229 PolarHBondContact O-N 2.97Å; E227-K229 VanDerWaalsContact O-N 3.09Å; E227-R230 HydrophobicContact CB-CB 4.08Å; E227-R230 WeakPolarHBondContact O-CB 3.31Å; E227-R230 PolarHBondContact O-N 3.1Å; E227-H231 PolarHBondContact O-CD2 2.96Å
228	K	63.6	Low	73.7	Confident	173 Å²	173	100.5 Å²	100.5	75%	0.752	46%	0.457	S	S	*	.	H	α-helix	trans	-52	-33.4	179.1	-69.8	-178.5	-179.3	176.4	0	113.7
229	K	60.3	Low	73.9	Confident	151 Å²	151	97.5 Å²	97.5	66%	0.657	44%	0.442	S	S	*	.	H	α-helix	trans	-69.5	-31.3	-179	-166.8	175.8	178.7	179.7	0	112.6	E227	E227-K229 PolarHBondContact O-N 2.97Å; E227-K229 VanDerWaalsContact O-N 3.09Å
230	R	66.5	Low	74	Confident	54 Å²	54	89.8 Å²	89.8	20%	0.204	41%	0.409	C	S	.	.	H	α-helix	trans	-69	-40.7	178.4	-167.7	170.2	66.7	161.8	2.5	111.5	V130 T220 L221 C224 E227 R232 V234	V130-R230 HydrophobicContact CG2-CG 3.84Å; T220-R230 PolarHBondContact O-NH2 3.46Å; L221-R230 HydrophobicContact CD2-CG 4.15Å; L221-R230 VanDerWaalsContact CD2-NE 3.32Å; C224-R230 PolarHBondContact O-NH2 2.89Å; E227-R230 HydrophobicContact CB-CB 4.08Å; E227-R230 WeakPolarHBondContact O-CB 3.31Å; E227-R230 PolarHBondContact O-N 3.1Å; R230-R232 VanDerWaalsContact C-N 3.34Å; R230-R232 PolarHBondContact O-N 2.82Å; R230-V234 WeakPolarHBondContact O-CG2 3.32Å; R230-V234 PolarHBondContact O-N 3.41Å
231	H	69.6	Low	74.3	Confident	78 Å²	78	88.3 Å²	88.3	36%	0.361	40%	0.4	S	S	.	.	H	α-helix	trans	-62	-37.7	177.5	-66.8	-80.8	0	0	0	113	E227 V234 R235	E227-H231 PolarHBondContact O-CD2 2.96Å; H231-V234 PolarHBondContact O-N 3.12Å; H231-R235 WeakPolarHBondContact O-CB 3.25Å; H231-R235 PolarHBondContact O-N 3.06Å
232	R	70.9	Confident	75.1	Confident	127 Å²	127	90 Å²	90	48%	0.479	41%	0.409	S	S	.	.	H	α-helix	trans	-65.8	-42.9	-178.1	-66.3	-177.3	-173.2	172.3	3.2	113	R230 R235 L236 E302	R230-R232 VanDerWaalsContact C-N 3.34Å; R230-R232 PolarHBondContact O-N 2.82Å; R232-R235 PolarHBondContact O-N 3.27Å; R232-L236 PolarHBondContact O-N 3.29Å; R232-L236 VanDerWaalsContact O-N 3.14Å; R232-E302 WeakPolarHBondContact CD-OE2 3.47Å; R232-E302 IonicContact CZ-OE1 3.55Å; R232-E302 IonicContact CZ-OE2 3.54Å; R232-E302 VanDerWaalsContact CZ-OE2 3.24Å; R232-E302 IonicContact NE-OE1 2.64Å; R232-E302 IonicContact NE-OE2 3.26Å; R232-E302 IonicContact NH1-OE1 3.24Å; R232-E302 IonicContact NH1-OE2 3.74Å; R232-E302 PolarHBondContact NH1-OE2 3.49Å
233	A	68.7	Low	75.8	Confident	36 Å²	36	84.5 Å²	84.5	30%	0.298	38%	0.381	S	S	.	.	H	α-helix	trans	-70.2	-38.2	179.6	0	0	0	0	0	112.2	L236 I237	A233-L236 PolarHBondContact O-N 3.43Å; A233-I237 PolarHBondContact O-N 3.3Å
234	V	77.1	Confident	76.6	Confident	15 Å²	15	74 Å²	74	9%	0.091	34%	0.341	C	S	.	.	H	α-helix	trans	-62.6	-43.8	173.4	172.8	0	0	0	0	110.6	V130 Y214 I217 L221 R230 H231 L236 I237 F238	V130-V234 HydrophobicContact CG2-CG2 4.03Å; Y214-V234 HydrophobicContact CE1-CG1 4.11Å; I217-V234 HydrophobicContact CG2-CG1 3.75Å; I217-V234 HydrophobicContact CG2-CG2 3.94Å; L221-V234 HydrophobicContact CD1-CG1 4.41Å; R230-V234 WeakPolarHBondContact O-CG2 3.32Å; R230-V234 PolarHBondContact O-N 3.41Å; H231-V234 PolarHBondContact O-N 3.12Å; V234-L236 PolarHBondContact O-N 2.81Å; V234-I237 PolarHBondContact O-N 3.3Å; V234-F238 VanDerWaalsContact O-CB 3.26Å; V234-F238 WeakPolarHBondContact O-CB 3.47Å; V234-F238 PolarHBondContact O-N 2.93Å
235	R	81.6	Confident	77.9	Confident	125 Å²	125	72.2 Å²	72.2	47%	0.472	33%	0.326	S	S	.	.	H	α-helix	trans	-57.6	-46	177.1	-173.2	177.3	69.8	-172.6	2.3	111.9	H231 R232 F238 T239	H231-R235 WeakPolarHBondContact O-CB 3.25Å; H231-R235 PolarHBondContact O-N 3.06Å; R232-R235 PolarHBondContact O-N 3.27Å; R235-F238 PolarHBondContact O-N 3.08Å; R235-T239 PolarHBondContact O-N 3.18Å; R235-T239 PolarHBondContact O-OG1 3.25Å
236	L	80.9	Confident	79.5	Confident	31 Å²	31	66.8 Å²	66.8	16%	0.162	31%	0.313	C	S	.	.	H	α-helix	trans	-59.5	-52.3	179.6	179.9	64.7	0	0	0	112	R232 A233 V234 F238 T239 I240 I296 Y297 V300	R232-L236 PolarHBondContact O-N 3.29Å; R232-L236 VanDerWaalsContact O-N 3.14Å; A233-L236 PolarHBondContact O-N 3.43Å; V234-L236 PolarHBondContact O-N 2.81Å; L236-F238 VanDerWaalsContact C-N 3.31Å; L236-F238 PolarHBondContact O-N 3.3Å; L236-T239 PolarHBondContact O-N 3.34Å; L236-I240 HydrophobicContact CG-CD1 4.26Å; L236-I240 WeakPolarHBondContact O-CG1 3.41Å; L236-I240 PolarHBondContact O-N 2.92Å; L236-I240 VanDerWaalsContact O-N 3.09Å; L236-I296 HydrophobicContact CD1-CG2 3.92Å; L236-Y297 HydrophobicContact CD1-CD1 4.24Å; L236-V300 HydrophobicContact CB-CG1 4.39Å; L236-V300 HydrophobicContact CD1-CB 3.84Å; L236-V300 HydrophobicContact CD1-CG1 3.85Å
237	I	81.3	Confident	81.4	Confident	6 Å²	6	61.9 Å²	61.9	3%	0.031	29%	0.285	C	S	.	.	H	α-helix	trans	-68.1	-34.5	-177.5	-58	-48.9	0	0	0	111.2	L122 R126 Y214 A233 V234 I240 M241	L122-I237 HydrophobicContact CB-CD1 4.35Å; L122-I237 HydrophobicContact CB-CG2 4.35Å; L122-I237 HydrophobicContact CD2-CD1 4.42Å; R126-I237 HydrophobicContact CG-CB 4.06Å; R126-I237 HydrophobicContact CG-CG1 3.48Å; R126-I237 VanDerWaalsContact CG-CG1 3.48Å; R126-I237 HydrophobicContact CG-CG2 4.31Å; Y214-I237 VanDerWaalsContact OH-C 3.23Å; A233-I237 PolarHBondContact O-N 3.3Å; V234-I237 PolarHBondContact O-N 3.3Å; I237-I240 HydrophobicContact CD1-CD1 3.79Å; I237-I240 PolarHBondContact O-N 3.36Å; I237-M241 PolarHBondContact O-N 3.21Å
238	F	86.1	Confident	82.9	Confident	85 Å²	85	56.6 Å²	56.6	37%	0.373	26%	0.26	S	S	.	.	H	α-helix	trans	-62.2	-44.6	173.8	-175.9	-103.1	0	0	0	111.6	M210 Y214 V234 R235 L236 I240 M241 I242	M210-F238 HydrophobicContact CE-CD2 4.15Å; M210-F238 HydrophobicContact CE-CE2 3.49Å; M210-F238 VanDerWaalsContact CE-CE2 3.49Å; M210-F238 HydrophobicContact CE-CZ 4.22Å; Y214-F238 AromaticContact CD1-CD2 3.71Å; Y214-F238 HydrophobicContact CD1-CD2 3.71Å; Y214-F238 HydrophobicContact CD1-CE2 4.4Å; Y214-F238 HydrophobicContact CD2-CD2 4.29Å; Y214-F238 HydrophobicContact CE1-CB 3.68Å; Y214-F238 AromaticContact CE1-CD2 3.49Å; Y214-F238 HydrophobicContact CE1-CD2 3.49Å; Y214-F238 VanDerWaalsContact CE1-CD2 3.49Å; Y214-F238 HydrophobicContact CE1-CG 4.03Å; Y214-F238 HydrophobicContact CE2-CD2 4.1Å; Y214-F238 HydrophobicContact CG-CD2 4.12Å; Y214-F238 AromaticContact CZ-CD2 3.71Å; Y214-F238 WeakPolarHBondContact OH-CA 3.28Å; Y214-F238 PolarHBondContact OH-N 3.35Å; V234-F238 VanDerWaalsContact O-CB 3.26Å; V234-F238 WeakPolarHBondContact O-CB 3.47Å; V234-F238 PolarHBondContact O-N 2.93Å; R235-F238 PolarHBondContact O-N 3.08Å; L236-F238 VanDerWaalsContact C-N 3.31Å; L236-F238 PolarHBondContact O-N 3.3Å; F238-I240 PolarHBondContact O-N 3.32Å; F238-M241 PolarHBondContact O-N 3.24Å; F238-I242 HydrophobicContact CD1-CG1 4.09Å; F238-I242 HydrophobicContact CD2-CG1 4.45Å; F238-I242 HydrophobicContact CE1-CD1 4.3Å; F238-I242 HydrophobicContact CE1-CG1 3.72Å; F238-I242 HydrophobicContact CE2-CD1 4.15Å; F238-I242 HydrophobicContact CE2-CG1 4.14Å; F238-I242 HydrophobicContact CG-CG1 4.45Å; F238-I242 HydrophobicContact CZ-CD1 3.85Å; F238-I242 HydrophobicContact CZ-CG1 3.76Å; F238-I242 WeakPolarHBondContact O-CG1 3.26Å; F238-I242 PolarHBondContact O-N 2.94Å
239	T	89.8	Confident	84.4	Confident	39 Å²	39	49.1 Å²	49.1	24%	0.239	23%	0.231	C	C	.	.	H	α-helix	trans	-60.3	-44.8	175.9	-58.5	0	0	0	0	111.8	R235 L236 M241 I242 V243 I296 V300	R235-T239 PolarHBondContact O-N 3.18Å; R235-T239 PolarHBondContact O-OG1 3.25Å; L236-T239 PolarHBondContact O-N 3.34Å; T239-M241 VanDerWaalsContact C-N 3.32Å; T239-M241 PolarHBondContact O-N 2.73Å; T239-I242 PolarHBondContact O-N 3.12Å; T239-V243 HydrophobicContact CG2-CG2 4.17Å; T239-V243 WeakPolarHBondContact O-CB 3.36Å; T239-V243 VanDerWaalsContact O-CG2 3.25Å; T239-V243 WeakPolarHBondContact O-CG2 3.24Å; T239-V243 PolarHBondContact O-N 2.96Å; T239-I296 HydrophobicContact CG2-CG2 4.04Å; T239-V300 HydrophobicContact CG2-CG2 4.25Å
240	I	88.9	Confident	86.1	Confident	1 Å²	1	44 Å²	44	1%	0.005	21%	0.213	C	C	.	.	H	α-helix	trans	-57.7	-46.5	177.4	-62.9	164	0	0	0	110.6	I119 L236 I237 F238 V243 Y244 I296 Y297	I119-I240 HydrophobicContact CD1-CG2 4.06Å; I119-I240 HydrophobicContact CG1-CG2 4.01Å; I119-I240 HydrophobicContact CG2-CG2 4.46Å; L236-I240 HydrophobicContact CG-CD1 4.26Å; L236-I240 WeakPolarHBondContact O-CG1 3.41Å; L236-I240 PolarHBondContact O-N 2.92Å; L236-I240 VanDerWaalsContact O-N 3.09Å; I237-I240 HydrophobicContact CD1-CD1 3.79Å; I237-I240 PolarHBondContact O-N 3.36Å; F238-I240 PolarHBondContact O-N 3.32Å; I240-V243 PolarHBondContact O-N 3.38Å; I240-Y244 PolarHBondContact O-N 2.87Å; I240-I296 HydrophobicContact CG1-CD1 4.39Å; I240-I296 HydrophobicContact CG1-CG2 3.95Å; I240-Y297 HydrophobicContact CD1-CE1 3.63Å; I240-Y297 HydrophobicContact CG1-CE1 4.28Å
241	M	89.3	Confident	87.5	Confident	0 Å²	0	42.5 Å²	42.5	0%	0	21%	0.207	C	C	.	.	H	α-helix	trans	-65.3	-45	-179.1	-173.8	67.6	77.7	0	0	112.6	I119 T123 P206 M210 I237 F238 T239 Y244 F245	I119-M241 HydrophobicContact CG2-CE 3.47Å; I119-M241 VanDerWaalsContact CG2-CE 3.47Å; I119-M241 HydrophobicContact CG2-SD 3.7Å; T123-M241 HydrophobicContact CG2-CE 4.39Å; T123-M241 WeakPolarHBondContact OG1-CE 3.34Å; P206-M241 HydrophobicContact CB-SD 4.31Å; M210-M241 HydrophobicContact CB-CG 4.43Å; M210-M241 HydrophobicContact CG-CG 4.16Å; M210-M241 HydrophobicContact SD-CG 3.98Å; I237-M241 PolarHBondContact O-N 3.21Å; F238-M241 PolarHBondContact O-N 3.24Å; T239-M241 VanDerWaalsContact C-N 3.32Å; T239-M241 PolarHBondContact O-N 2.73Å; M241-Y244 WeakPolarHBondContact O-CB 3.28Å; M241-Y244 PolarHBondContact O-N 3.22Å; M241-F245 HydrophobicContact CG-CD2 4.1Å; M241-F245 HydrophobicContact CG-CE2 3.59Å; M241-F245 WeakPolarHBondContact O-CD2 3.48Å; M241-F245 PolarHBondContact O-N 2.67Å; M241-F245 VanDerWaalsContact O-N 3.15Å; M241-F245 HydrophobicContact SD-CD2 4.45Å; M241-F245 HydrophobicContact SD-CE2 3.67Å; M241-F245 HydrophobicContact SD-CZ 4.04Å
242	I	93.1	Very high	88.8	Confident	58 Å²	58	38.9 Å²	38.9	30%	0.297	19%	0.19	S	C	.	.	H	α-helix	trans	-63.2	-44.8	178.1	-66.4	-63.9	0	0	0	110.9	M210 F238 T239 Y244 F245 L246	M210-I242 HydrophobicContact CE-CD1 3.3Å; M210-I242 HydrophobicContact CE-CG1 4.22Å; M210-I242 HydrophobicContact SD-CD1 4.42Å; F238-I242 HydrophobicContact CD1-CG1 4.09Å; F238-I242 HydrophobicContact CD2-CG1 4.45Å; F238-I242 HydrophobicContact CE1-CD1 4.3Å; F238-I242 HydrophobicContact CE1-CG1 3.72Å; F238-I242 HydrophobicContact CE2-CD1 4.15Å; F238-I242 HydrophobicContact CE2-CG1 4.14Å; F238-I242 HydrophobicContact CG-CG1 4.45Å; F238-I242 HydrophobicContact CZ-CD1 3.85Å; F238-I242 HydrophobicContact CZ-CG1 3.76Å; F238-I242 WeakPolarHBondContact O-CG1 3.26Å; F238-I242 PolarHBondContact O-N 2.94Å; T239-I242 PolarHBondContact O-N 3.12Å; I242-Y244 VanDerWaalsContact C-N 3.29Å; I242-Y244 PolarHBondContact O-N 3.4Å; I242-F245 PolarHBondContact O-N 2.91Å; I242-F245 VanDerWaalsContact O-N 3.16Å; I242-L246 HydrophobicContact CG2-CD1 4.01Å; I242-L246 HydrophobicContact CG2-CG 4.29Å; I242-L246 WeakPolarHBondContact O-CG 3.16Å; I242-L246 PolarHBondContact O-N 3.05Å
243	V	95	Very high	89.9	Confident	22 Å²	22	37 Å²	37	13%	0.133	19%	0.189	C	C	.	.	H	α-helix	trans	-62.7	-39.3	178.5	172.6	0	0	0	0	110.9	T239 I240 F245 L246 F247 I292 I296	T239-V243 HydrophobicContact CG2-CG2 4.17Å; T239-V243 WeakPolarHBondContact O-CB 3.36Å; T239-V243 VanDerWaalsContact O-CG2 3.25Å; T239-V243 WeakPolarHBondContact O-CG2 3.24Å; T239-V243 PolarHBondContact O-N 2.96Å; I240-V243 PolarHBondContact O-N 3.38Å; V243-F245 VanDerWaalsContact C-N 3.35Å; V243-F245 PolarHBondContact O-N 3.04Å; V243-L246 PolarHBondContact O-N 2.84Å; V243-F247 HydrophobicContact CG1-CD2 3.88Å; V243-F247 HydrophobicContact CG1-CE2 3.84Å; V243-F247 WeakPolarHBondContact O-CD2 3.47Å; V243-F247 PolarHBondContact O-N 3.14Å; V243-F247 VanDerWaalsContact O-N 3.14Å; V243-I292 HydrophobicContact CG1-CG2 3.71Å; V243-I296 HydrophobicContact CB-CD1 3.92Å; V243-I296 HydrophobicContact CG1-CD1 3.97Å; V243-I296 HydrophobicContact CG2-CD1 3.98Å
244	Y	93.8	Very high	91.2	Very high	5 Å²	5	36.1 Å²	36.1	2%	0.02	18%	0.18	C	C	.	.	H	α-helix	trans	-55	-49.6	172.2	175.5	-91.8	0	0	0	111.8	I116 I119 G202 I240 M241 I242 L246 F247 W248 H289	I116-Y244 HydrophobicContact CB-CE2 4.1Å; I116-Y244 HydrophobicContact CD1-CD1 3.67Å; I116-Y244 HydrophobicContact CD1-CD2 4.22Å; I116-Y244 HydrophobicContact CD1-CE1 3.31Å; I116-Y244 HydrophobicContact CD1-CE2 3.91Å; I116-Y244 HydrophobicContact CD1-CG 4.12Å; I116-Y244 VanDerWaalsContact CD1-CZ 3.45Å; I116-Y244 HydrophobicContact CG1-CE1 3.95Å; I116-Y244 HydrophobicContact CG1-CE2 4.33Å; I119-Y244 HydrophobicContact CD1-CD2 3.96Å; I119-Y244 HydrophobicContact CD1-CG 4.26Å; G202-Y244 VanDerWaalsContact O-CE1 3.3Å; G202-Y244 WeakPolarHBondContact O-CE1 3.21Å; G202-Y244 PolarHBondContact O-OH 3.06Å; G202-Y244 VanDerWaalsContact O-OH 3.07Å; I240-Y244 PolarHBondContact O-N 2.87Å; M241-Y244 WeakPolarHBondContact O-CB 3.28Å; M241-Y244 PolarHBondContact O-N 3.22Å; I242-Y244 VanDerWaalsContact C-N 3.29Å; I242-Y244 PolarHBondContact O-N 3.4Å; Y244-L246 PolarHBondContact O-N 2.67Å; Y244-F247 PolarHBondContact O-N 2.86Å; Y244-W248 AromaticContact CD2-CD1 3.49Å; Y244-W248 VanDerWaalsContact CD2-CD1 3.49Å; Y244-W248 HydrophobicContact CD2-CG 4.28Å; Y244-W248 HydrophobicContact CE1-CB 4.2Å; Y244-W248 HydrophobicContact CE2-CB 4.17Å; Y244-W248 AromaticContact CE2-CD1 3.32Å; Y244-W248 AromaticContact CE2-CG 3.8Å; Y244-W248 HydrophobicContact CE2-CG 3.8Å; Y244-W248 AromaticContact CE2-NE1 3.91Å; Y244-W248 AromaticContact CZ-CD1 3.98Å; Y244-W248 WeakPolarHBondContact O-CB 3.33Å; Y244-W248 PolarHBondContact O-N 3.01Å; Y244-H289 AromaticContact CD2-CE1 3.85Å; Y244-H289 AromaticContact CD2-NE2 3.93Å
245	F	94.9	Very high	92	Very high	25 Å²	25	36.2 Å²	36.2	11%	0.11	18%	0.18	C	C	.	.	H	α-helix	trans	-64.6	-39.1	178.8	-71.3	-57.1	0	0	0	113.1	L203 P206 L207 M210 M241 I242 V243 F247 A249	L203-F245 HydrophobicContact CD1-CD1 3.78Å; L203-F245 HydrophobicContact CD1-CE1 3.87Å; P206-F245 HydrophobicContact CB-CE1 4.27Å; P206-F245 HydrophobicContact CB-CZ 3.87Å; P206-F245 HydrophobicContact CG-CE1 4.02Å; P206-F245 HydrophobicContact CG-CZ 4.12Å; L207-F245 HydrophobicContact CB-CE1 4.33Å; L207-F245 HydrophobicContact CB-CZ 4.05Å; L207-F245 HydrophobicContact CD1-CE2 4.48Å; L207-F245 HydrophobicContact CD1-CZ 4.31Å; M210-F245 HydrophobicContact SD-CD2 4.09Å; M210-F245 HydrophobicContact SD-CE2 3.57Å; M210-F245 VanDerWaalsContact SD-CE2 3.57Å; M241-F245 HydrophobicContact CG-CD2 4.1Å; M241-F245 HydrophobicContact CG-CE2 3.59Å; M241-F245 WeakPolarHBondContact O-CD2 3.48Å; M241-F245 PolarHBondContact O-N 2.67Å; M241-F245 VanDerWaalsContact O-N 3.15Å; M241-F245 HydrophobicContact SD-CD2 4.45Å; M241-F245 HydrophobicContact SD-CE2 3.67Å; M241-F245 HydrophobicContact SD-CZ 4.04Å; I242-F245 PolarHBondContact O-N 2.91Å; I242-F245 VanDerWaalsContact O-N 3.16Å; V243-F245 VanDerWaalsContact C-N 3.35Å; V243-F245 PolarHBondContact O-N 3.04Å; F245-F247 PolarHBondContact O-N 3.19Å; F245-A249 WeakPolarHBondContact O-CA 3.07Å; F245-A249 WeakPolarHBondContact O-CB 3.27Å; F245-A249 PolarHBondContact O-N 3.41Å
246	L	96.4	Very high	92.6	Very high	112 Å²	112	32.9 Å²	32.9	59%	0.586	17%	0.171	S	C	*	.	H	α-helix	trans	-59.8	-34.1	177.1	-70.1	172.4	0	0	0	112.3	I242 V243 Y244	I242-L246 HydrophobicContact CG2-CD1 4.01Å; I242-L246 HydrophobicContact CG2-CG 4.29Å; I242-L246 WeakPolarHBondContact O-CG 3.16Å; I242-L246 PolarHBondContact O-N 3.05Å; V243-L246 PolarHBondContact O-N 2.84Å; Y244-L246 PolarHBondContact O-N 2.67Å
247	F	96.1	Very high	93.1	Very high	39 Å²	39	33.7 Å²	33.7	17%	0.171	18%	0.175	C	C	.	.	H	α-helix	trans	-90.2	-38.8	-177.2	-78.2	-116.3	0	0	0	112.7	V243 Y244 F245 L285 T288 H289 I292	V243-F247 HydrophobicContact CG1-CD2 3.88Å; V243-F247 HydrophobicContact CG1-CE2 3.84Å; V243-F247 WeakPolarHBondContact O-CD2 3.47Å; V243-F247 PolarHBondContact O-N 3.14Å; V243-F247 VanDerWaalsContact O-N 3.14Å; Y244-F247 PolarHBondContact O-N 2.86Å; F245-F247 PolarHBondContact O-N 3.19Å; F247-L285 HydrophobicContact CD1-CD1 3.92Å; F247-L285 HydrophobicContact CD1-CG 4.24Å; F247-L285 VanDerWaalsContact CD1-O 3.31Å; F247-L285 WeakPolarHBondContact CD1-O 3.49Å; F247-L285 HydrophobicContact CE1-CD1 4.03Å; F247-L285 HydrophobicContact CG-CD1 4.4Å; F247-L285 HydrophobicContact CG-CG 4.46Å; F247-T288 WeakPolarHBondContact CD1-OG1 3.06Å; F247-T288 VanDerWaalsContact CE1-OG1 3.25Å; F247-T288 WeakPolarHBondContact CE1-OG1 3.49Å; F247-H289 HydrophobicContact CB-CB 3.94Å; F247-H289 HydrophobicContact CD1-CB 3.93Å; F247-H289 HydrophobicContact CG-CB 4.17Å; F247-I292 HydrophobicContact CE1-CD1 4.24Å; F247-I292 HydrophobicContact CE1-CG1 3.81Å; F247-I292 HydrophobicContact CZ-CD1 4.14Å; F247-I292 HydrophobicContact CZ-CG1 3.88Å
248	W	96.3	Very high	93.5	Very high	7 Å²	7	35 Å²	35	3%	0.027	18%	0.183	C	C	.	.	H	α-helix	trans	-102.2	-27.9	-172.4	-75.8	103.1	0	0	0	115	F79 F112 Y244 P250 Y251 N252 G286 H289	F79-W248 HydrophobicContact CE2-CH2 4.09Å; F79-W248 HydrophobicContact CE2-CZ2 4.2Å; F79-W248 AromaticContact CZ-CH2 3.99Å; F79-W248 HydrophobicContact CZ-CH2 3.99Å; F79-W248 HydrophobicContact CZ-CZ2 4.08Å; F112-W248 HydrophobicContact CD2-CD2 4.2Å; F112-W248 HydrophobicContact CD2-CE3 4.05Å; F112-W248 AromaticContact CD2-CH2 3.56Å; F112-W248 HydrophobicContact CD2-CH2 3.56Å; F112-W248 AromaticContact CD2-CZ2 3.74Å; F112-W248 HydrophobicContact CD2-CZ2 3.74Å; F112-W248 AromaticContact CD2-CZ3 3.73Å; F112-W248 HydrophobicContact CD2-CZ3 3.73Å; F112-W248 AromaticContact CE2-CD2 3.69Å; F112-W248 HydrophobicContact CE2-CD2 3.69Å; F112-W248 AromaticContact CE2-CE3 3.45Å; F112-W248 HydrophobicContact CE2-CE3 3.45Å; F112-W248 VanDerWaalsContact CE2-CE3 3.45Å; F112-W248 HydrophobicContact CE2-CG 4.42Å; F112-W248 AromaticContact CE2-CH2 3.87Å; F112-W248 HydrophobicContact CE2-CH2 3.87Å; F112-W248 HydrophobicContact CE2-CZ2 4.11Å; F112-W248 AromaticContact CE2-CZ3 3.54Å; F112-W248 HydrophobicContact CE2-CZ3 3.54Å; F112-W248 HydrophobicContact CZ-CE3 4.44Å; Y244-W248 AromaticContact CD2-CD1 3.49Å; Y244-W248 VanDerWaalsContact CD2-CD1 3.49Å; Y244-W248 HydrophobicContact CD2-CG 4.28Å; Y244-W248 HydrophobicContact CE1-CB 4.2Å; Y244-W248 HydrophobicContact CE2-CB 4.17Å; Y244-W248 AromaticContact CE2-CD1 3.32Å; Y244-W248 AromaticContact CE2-CG 3.8Å; Y244-W248 HydrophobicContact CE2-CG 3.8Å; Y244-W248 AromaticContact CE2-NE1 3.91Å; Y244-W248 AromaticContact CZ-CD1 3.98Å; Y244-W248 WeakPolarHBondContact O-CB 3.33Å; Y244-W248 PolarHBondContact O-N 3.01Å; W248-P250 VanDerWaalsContact C-CD 3.48Å; W248-Y251 HydrophobicContact CE3-CD1 4.09Å; W248-Y251 HydrophobicContact CZ3-CD1 4.1Å; W248-Y251 HydrophobicContact CZ3-CE1 4.5Å; W248-Y251 PolarHBondContact O-N 2.87Å; W248-N252 PolarHBondContact O-N 3.05Å; W248-N252 VanDerWaalsContact O-N 3.09Å; W248-N252 PolarHBondContact O-ND2 3.31Å; W248-G286 VanDerWaalsContact CZ2-O 3.23Å; W248-G286 WeakPolarHBondContact CZ2-O 3.34Å; W248-H289 AromaticContact CD1-CG 3.88Å; W248-H289 AromaticContact NE1-CG 3.54Å; W248-H289 AromaticContact NE1-ND1 3.61Å
249	A	95.4	Very high	93.7	Very high	16 Å²	16	31.4 Å²	31.4	13%	0.132	17%	0.167	C	C	.	.	H	α-helix	trans	-60.5	-40.3	178.8	0	0	0	0	0	112.8	L203 F245 Y251 N252 I253	L203-A249 HydrophobicContact CD1-CB 3.76Å; F245-A249 WeakPolarHBondContact O-CA 3.07Å; F245-A249 WeakPolarHBondContact O-CB 3.27Å; F245-A249 PolarHBondContact O-N 3.41Å; A249-Y251 VanDerWaalsContact C-N 3.31Å; A249-Y251 PolarHBondContact O-N 3.2Å; A249-N252 PolarHBondContact O-N 3.49Å; A249-I253 WeakPolarHBondContact O-CD1 3.44Å; A249-I253 VanDerWaalsContact O-CG1 3.25Å; A249-I253 WeakPolarHBondContact O-CG1 3.34Å; A249-I253 PolarHBondContact O-N 2.88Å
250	P	97.2	Very high	93.8	Very high	42 Å²	42	32 Å²	32	27%	0.273	17%	0.167	S	C	.	.	H	α-helix	trans	-55.1	-45.7	175.8	-26.9	36.2	0	0	0	112.5	W248 I253 V254 T282 L285	W248-P250 VanDerWaalsContact C-CD 3.48Å; P250-I253 PolarHBondContact O-N 2.86Å; P250-V254 VanDerWaalsContact O-CG2 3.31Å; P250-V254 WeakPolarHBondContact O-CG2 3.32Å; P250-V254 PolarHBondContact O-N 3.12Å; P250-T282 HydrophobicContact CB-CG2 3.61Å; P250-L285 HydrophobicContact CG-CD2 4.27Å
251	Y	95.9	Very high	93.7	Very high	24 Å²	24	34 Å²	34	9%	0.094	18%	0.176	C	C	.	.	H	α-helix	trans	-63.4	-46.5	178.1	173.5	-104.3	0	0	0	112	W248 A249 I253 V254 L255 T279 T282 E283	W248-Y251 HydrophobicContact CE3-CD1 4.09Å; W248-Y251 HydrophobicContact CZ3-CD1 4.1Å; W248-Y251 HydrophobicContact CZ3-CE1 4.5Å; W248-Y251 PolarHBondContact O-N 2.87Å; A249-Y251 VanDerWaalsContact C-N 3.31Å; A249-Y251 PolarHBondContact O-N 3.2Å; Y251-I253 VanDerWaalsContact C-N 3.31Å; Y251-I253 PolarHBondContact O-N 3.24Å; Y251-V254 PolarHBondContact O-N 2.03Å; Y251-L255 HydrophobicContact CE1-CD2 4.19Å; Y251-L255 VanDerWaalsContact O-CB 3.26Å; Y251-L255 WeakPolarHBondContact O-CB 3.25Å; Y251-L255 PolarHBondContact O-N 2.97Å; Y251-T279 HydrophobicContact CE2-CG2 4.19Å; Y251-T282 WeakPolarHBondContact CA-OG1 3.34Å; Y251-E283 HydrophobicContact CD2-CB 3.66Å; Y251-E283 HydrophobicContact CD2-CG 4.33Å; Y251-E283 HydrophobicContact CE2-CB 3.7Å; Y251-E283 HydrophobicContact CE2-CG 4.02Å
252	N	95.2	Very high	93.4	Very high	1 Å²	1	41 Å²	41	1%	0.005	21%	0.208	C	C	.	.	H	α-helix	trans	-61.6	-39.1	179.4	-77.9	-87	0	0	0	112.2	I198 V199 L203 W248 A249 L256	I198-N252 WeakPolarHBondContact CG2-OD1 3.3Å; I198-N252 PolarHBondContact O-OD1 3.26Å; V199-N252 HydrophobicContact CG2-CB 4.4Å; L203-N252 HydrophobicContact CB-CB 4.21Å; L203-N252 HydrophobicContact CD2-CB 3.97Å; W248-N252 PolarHBondContact O-N 3.05Å; W248-N252 VanDerWaalsContact O-N 3.09Å; W248-N252 PolarHBondContact O-ND2 3.31Å; A249-N252 PolarHBondContact O-N 3.49Å; N252-L256 PolarHBondContact O-N 3.26Å; N252-L256 VanDerWaalsContact O-N 3.11Å
253	I	95.4	Very high	93.2	Very high	89 Å²	89	46.2 Å²	46.2	46%	0.456	23%	0.23	S	C	.	.	H	α-helix	trans	-66.6	-47.7	177	-66.8	163.7	0	0	0	110.3	L203 A249 P250 Y251 L255 L256 L257	L203-I253 HydrophobicContact CD2-CG1 4.48Å; A249-I253 WeakPolarHBondContact O-CD1 3.44Å; A249-I253 VanDerWaalsContact O-CG1 3.25Å; A249-I253 WeakPolarHBondContact O-CG1 3.34Å; A249-I253 PolarHBondContact O-N 2.88Å; P250-I253 PolarHBondContact O-N 2.86Å; Y251-I253 VanDerWaalsContact C-N 3.31Å; Y251-I253 PolarHBondContact O-N 3.24Å; I253-L255 VanDerWaalsContact C-N 3.34Å; I253-L255 PolarHBondContact O-N 2.99Å; I253-L256 WeakPolarHBondContact O-CB 3.44Å; I253-L256 PolarHBondContact O-N 3.16Å; I253-L257 HydrophobicContact CG2-CD1 4.23Å; I253-L257 WeakPolarHBondContact O-CG 3.41Å; I253-L257 PolarHBondContact O-N 3.07Å
254	V	94.9	Very high	92.8	Very high	17 Å²	17	49.9 Å²	49.9	10%	0.103	24%	0.244	C	C	.	.	H	α-helix	trans	-65.6	-38	179.4	176.5	0	0	0	0	111.4	P250 Y251 L256 L257 N258 L275 A278 T279 T282	P250-V254 VanDerWaalsContact O-CG2 3.31Å; P250-V254 WeakPolarHBondContact O-CG2 3.32Å; P250-V254 PolarHBondContact O-N 3.12Å; Y251-V254 PolarHBondContact O-N 2.03Å; V254-L256 VanDerWaalsContact C-N 3.31Å; V254-L256 PolarHBondContact O-N 3.08Å; V254-L257 PolarHBondContact O-N 3.22Å; V254-N258 WeakPolarHBondContact O-CB 3.18Å; V254-N258 PolarHBondContact O-N 3.14Å; V254-L275 HydrophobicContact CG1-CD2 4.47Å; V254-A278 HydrophobicContact CG1-CB 3.91Å; V254-A278 HydrophobicContact CG2-CB 4.15Å; V254-T279 VanDerWaalsContact CG1-OG1 3.31Å; V254-T279 WeakPolarHBondContact CG1-OG1 3.32Å; V254-T282 HydrophobicContact CG2-CG2 4.11Å
255	L	93.7	Very high	92.2	Very high	17 Å²	17	51.9 Å²	51.9	9%	0.089	27%	0.266	C	S	.	.	H	α-helix	trans	-60.9	-40.1	175	-176.9	66.5	0	0	0	111.8	T195 I198 Y251 I253 T259	T195-L255 HydrophobicContact CG2-CD2 4.38Å; T195-L255 HydrophobicContact CG2-CG 4.02Å; I198-L255 HydrophobicContact CB-CD2 4.11Å; I198-L255 HydrophobicContact CD1-CD2 4.05Å; I198-L255 HydrophobicContact CG2-CD2 3.86Å; Y251-L255 HydrophobicContact CE1-CD2 4.19Å; Y251-L255 VanDerWaalsContact O-CB 3.26Å; Y251-L255 WeakPolarHBondContact O-CB 3.25Å; Y251-L255 PolarHBondContact O-N 2.97Å; I253-L255 VanDerWaalsContact C-N 3.34Å; I253-L255 PolarHBondContact O-N 2.99Å; L255-T259 WeakPolarHBondContact O-CB 3.45Å; L255-T259 PolarHBondContact O-N 2.8Å; L255-T259 PolarHBondContact O-OG1 2.88Å
256	L	94.3	Very high	91.6	Very high	54 Å²	54	53.1 Å²	53.1	28%	0.283	27%	0.273	S	S	.	.	H	α-helix	trans	-63.4	-48.8	174.3	-170	75.9	0	0	0	111	T195 V199 N252 I253 V254 N258 T259 F260	T195-L256 HydrophobicContact CG2-CD1 4.35Å; V199-L256 HydrophobicContact CG2-CB 4.48Å; V199-L256 HydrophobicContact CG2-CD1 4.44Å; N252-L256 PolarHBondContact O-N 3.26Å; N252-L256 VanDerWaalsContact O-N 3.11Å; I253-L256 WeakPolarHBondContact O-CB 3.44Å; I253-L256 PolarHBondContact O-N 3.16Å; V254-L256 VanDerWaalsContact C-N 3.31Å; V254-L256 PolarHBondContact O-N 3.08Å; L256-N258 VanDerWaalsContact C-N 3.34Å; L256-N258 PolarHBondContact O-N 3.21Å; L256-T259 PolarHBondContact O-N 3.11Å; L256-F260 HydrophobicContact CD1-CD2 3.7Å; L256-F260 HydrophobicContact CD1-CE2 3.59Å; L256-F260 HydrophobicContact CG-CD2 4.08Å; L256-F260 HydrophobicContact CG-CE2 4.46Å; L256-F260 WeakPolarHBondContact O-CD2 3.32Å; L256-F260 PolarHBondContact O-N 2.85Å
257	L	92.9	Very high	90.8	Very high	48 Å²	48	52.3 Å²	52.3	25%	0.251	27%	0.27	S	S	.	.	H	α-helix	trans	-60.3	-42.5	177.7	-68.8	173.2	0	0	0	112.1	I253 V254 T259 F260 Q261 F264 L275	I253-L257 HydrophobicContact CG2-CD1 4.23Å; I253-L257 WeakPolarHBondContact O-CG 3.41Å; I253-L257 PolarHBondContact O-N 3.07Å; V254-L257 PolarHBondContact O-N 3.22Å; L257-T259 VanDerWaalsContact C-N 3.32Å; L257-T259 PolarHBondContact O-N 3.44Å; L257-F260 CarbonylContact O-C 3.59Å; L257-F260 PolarHBondContact O-N 3.36Å; L257-Q261 WeakPolarHBondContact O-CA 3.44Å; L257-Q261 PolarHBondContact O-N 2.9Å; L257-Q261 VanDerWaalsContact O-N 3.11Å; L257-F264 HydrophobicContact CD2-CD1 4.47Å; L257-F264 HydrophobicContact CD2-CD2 3.77Å; L257-F264 HydrophobicContact CD2-CE2 3.88Å; L257-F264 HydrophobicContact CD2-CG 4.1Å; L257-F264 HydrophobicContact CD2-CZ 4.29Å; L257-L275 HydrophobicContact CB-CD2 3.91Å; L257-L275 HydrophobicContact CD1-CD2 4.5Å
258	N	89.9	Confident	90.2	Very high	35 Å²	35	55.1 Å²	55.1	19%	0.187	29%	0.286	C	S	.	.	H	α-helix	trans	-66.4	-34.5	178.7	-169.6	36.4	0	0	0	112.3	V254 L256	V254-N258 WeakPolarHBondContact O-CB 3.18Å; V254-N258 PolarHBondContact O-N 3.14Å; L256-N258 VanDerWaalsContact C-N 3.34Å; L256-N258 PolarHBondContact O-N 3.21Å
259	T	90.1	Very high	89.5	Confident	8 Å²	8	58.2 Å²	58.2	5%	0.049	31%	0.308	C	S	.	.	H	α-helix	trans	-74	-40.5	178.9	-59.2	0	0	0	0	112	K191 N192 T195 L255 L256 L257	K191-T259 HydrophobicContact CG-CG2 4.18Å; N192-T259 WeakPolarHBondContact OD1-CG2 3.47Å; T195-T259 WeakPolarHBondContact CB-OG1 3.46Å; T195-T259 HydrophobicContact CG2-CG2 4.17Å; T195-T259 WeakPolarHBondContact CG2-OG1 3.41Å; T195-T259 PolarHBondContact OG1-OG1 2.82Å; L255-T259 WeakPolarHBondContact O-CB 3.45Å; L255-T259 PolarHBondContact O-N 2.8Å; L255-T259 PolarHBondContact O-OG1 2.88Å; L256-T259 PolarHBondContact O-N 3.11Å; L257-T259 VanDerWaalsContact C-N 3.32Å; L257-T259 PolarHBondContact O-N 3.44Å
260	F	90.4	Very high	88.9	Confident	52 Å²	52	61 Å²	61	23%	0.228	33%	0.327	C	S	.	.	T	Hydrogen-bonded Turn	trans	-105	35	-176.2	-61.7	-71.1	0	0	0	112.6	L196 L256 L257 E262 F263 F264	L196-F260 HydrophobicContact CD2-CE2 4.35Å; L196-F260 HydrophobicContact CD2-CZ 4.42Å; L256-F260 HydrophobicContact CD1-CD2 3.7Å; L256-F260 HydrophobicContact CD1-CE2 3.59Å; L256-F260 HydrophobicContact CG-CD2 4.08Å; L256-F260 HydrophobicContact CG-CE2 4.46Å; L256-F260 WeakPolarHBondContact O-CD2 3.32Å; L256-F260 PolarHBondContact O-N 2.85Å; L257-F260 CarbonylContact O-C 3.59Å; L257-F260 PolarHBondContact O-N 3.36Å; F260-E262 PolarHBondContact O-N 3.22Å; F260-F263 HydrophobicContact CB-CB 4.26Å; F260-F263 WeakPolarHBondContact O-CB 3.33Å; F260-F263 PolarHBondContact O-N 2.68Å; F260-F263 VanDerWaalsContact O-N 3.1Å; F260-F264 HydrophobicContact CB-CD2 4.02Å; F260-F264 HydrophobicContact CB-CE2 3.88Å; F260-F264 VanDerWaalsContact O-CD2 3.23Å; F260-F264 WeakPolarHBondContact O-CD2 3.31Å; F260-F264 PolarHBondContact O-N 3.48Å; F260-F264 VanDerWaalsContact O-N 3.15Å
261	Q	87.4	Confident	88.2	Confident	42 Å²	42	60.5 Å²	60.5	20%	0.196	33%	0.325	C	S	.	.	T	Hydrogen-bonded Turn	trans	-55.2	-37.7	-177.5	64.1	178.2	-24.3	0	0	113.4	L257 F264 G265 L266	L257-Q261 WeakPolarHBondContact O-CA 3.44Å; L257-Q261 PolarHBondContact O-N 2.9Å; L257-Q261 VanDerWaalsContact O-N 3.11Å; Q261-F264 PolarHBondContact O-N 3.33Å; Q261-G265 PolarHBondContact O-N 2.97Å; Q261-L266 HydrophobicContact CB-CB 4.27Å; Q261-L266 PolarHBondContact O-N 3.48Å
262	E	84	Confident	87.6	Confident	147 Å²	147	60.5 Å²	60.5	69%	0.687	33%	0.328	S	S	*	.	T	Hydrogen-bonded Turn	trans	-67.2	-41.1	179.8	-69	174.8	-168.9	0	0	111.3	F260 F264 G265 N267	F260-E262 PolarHBondContact O-N 3.22Å; E262-F264 VanDerWaalsContact C-N 3.31Å; E262-F264 PolarHBondContact O-N 2.78Å; E262-G265 PolarHBondContact O-N 2.59Å; E262-N267 HydrophobicContact CG-CB 4.44Å
263	F	87.5	Confident	87.1	Confident	169 Å²	169	62.3 Å²	62.3	74%	0.741	34%	0.338	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.1	-35.7	177.9	-176.1	-96	0	0	0	112.1	F260	F260-F263 HydrophobicContact CB-CB 4.26Å; F260-F263 WeakPolarHBondContact O-CB 3.33Å; F260-F263 PolarHBondContact O-N 2.68Å; F260-F263 VanDerWaalsContact O-N 3.1Å
264	F	86.1	Confident	86.6	Confident	99 Å²	99	67 Å²	67	43%	0.434	35%	0.35	S	S	.	.	T	Hydrogen-bonded Turn	trans	-89.8	1.8	178.1	-66.8	-66	0	0	0	114.1	L257 F260 Q261 E262 L266	L257-F264 HydrophobicContact CD2-CD1 4.47Å; L257-F264 HydrophobicContact CD2-CD2 3.77Å; L257-F264 HydrophobicContact CD2-CE2 3.88Å; L257-F264 HydrophobicContact CD2-CG 4.1Å; L257-F264 HydrophobicContact CD2-CZ 4.29Å; F260-F264 HydrophobicContact CB-CD2 4.02Å; F260-F264 HydrophobicContact CB-CE2 3.88Å; F260-F264 VanDerWaalsContact O-CD2 3.23Å; F260-F264 WeakPolarHBondContact O-CD2 3.31Å; F260-F264 PolarHBondContact O-N 3.48Å; F260-F264 VanDerWaalsContact O-N 3.15Å; Q261-F264 PolarHBondContact O-N 3.33Å; E262-F264 VanDerWaalsContact C-N 3.31Å; E262-F264 PolarHBondContact O-N 2.78Å; F264-L266 VanDerWaalsContact C-N 3.34Å; F264-L266 HydrophobicContact CB-CD1 4.01Å; F264-L266 HydrophobicContact CB-CG 4.09Å; F264-L266 PolarHBondContact O-N 3.02Å
265	G	82.3	Confident	86.3	Confident	47 Å²	47	67 Å²	67	49%	0.485	35%	0.349	S	S	.	.	T	Hydrogen-bonded Turn	trans	67.3	29.4	-178.5	0	0	0	0	0	114.5	Q261 E262	Q261-G265 PolarHBondContact O-N 2.97Å; E262-G265 PolarHBondContact O-N 2.59Å
266	L	83	Confident	85.8	Confident	50 Å²	50	67.9 Å²	67.9	26%	0.262	35%	0.354	S	S	.	.			trans	-104.7	16.7	-176.8	-61.6	175.6	0	0	0	113.6	Q261 F264 N268 S271 L275	Q261-L266 HydrophobicContact CB-CB 4.27Å; Q261-L266 PolarHBondContact O-N 3.48Å; F264-L266 VanDerWaalsContact C-N 3.34Å; F264-L266 HydrophobicContact CB-CD1 4.01Å; F264-L266 HydrophobicContact CB-CG 4.09Å; F264-L266 PolarHBondContact O-N 3.02Å; L266-N268 PolarHBondContact O-N 3.31Å; L266-S271 WeakPolarHBondContact O-CB 3.07Å; L266-L275 HydrophobicContact CB-CD1 4.01Å; L266-L275 HydrophobicContact CD1-CD1 3.98Å
267	N	78.3	Confident	85.4	Confident	96 Å²	96	69 Å²	69	51%	0.513	36%	0.358	S	S	.	.			trans	-75.5	0.2	-174.8	63.6	-26	0	0	0	115.2	E262	E262-N267 HydrophobicContact CG-CB 4.44Å
268	N	84.3	Confident	85.3	Confident	97 Å²	97	68.3 Å²	68.3	52%	0.519	36%	0.359	S	S	.	.	S	Bend	trans	-73.8	144	175.7	-62.2	-12.1	0	0	0	110.9	L266 S270 S271 S272	L266-N268 PolarHBondContact O-N 3.31Å; N268-S270 VanDerWaalsContact C-N 3.27Å; N268-S270 PolarHBondContact O-N 3.34Å; N268-S271 PolarHBondContact O-N 3.15Å; N268-S272 PolarHBondContact O-N 3.08Å
269	C	80.8	Confident	85.4	Confident	72 Å²	72	67.7 Å²	67.7	49%	0.486	36%	0.357	S	S	.	.	H	α-helix	trans	-57.1	-35.5	-177.8	165.2	0	0	0	0	113.2	C20 N273	C20-C269 HydrophobicContact CB-CB 4.07Å; C20-C269 WeakPolarHBondContact CB-SG 3.48Å; C20-C269 WeakPolarHBondContact SG-CB 3.45Å; C20-C269 PolarHBondContact SG-O 3.47Å; C20-C269 CovalentContact SG-SG 2.06Å; C20-C269 PolarHBondContact SG-SG 3.01Å; C269-N273 VanDerWaalsContact O-CB 3.29Å; C269-N273 WeakPolarHBondContact O-CB 3.46Å; C269-N273 PolarHBondContact O-N 2.95Å
270	S	82.9	Confident	85.3	Confident	75 Å²	75	70.4 Å²	70.4	52%	0.524	37%	0.369	S	S	.	.	H	α-helix	trans	-65.1	-42	175	57.8	0	0	0	0	112.9	N268 R274	N268-S270 VanDerWaalsContact C-N 3.27Å; N268-S270 PolarHBondContact O-N 3.34Å; S270-R274 WeakPolarHBondContact O-CG 3.35Å; S270-R274 PolarHBondContact O-N 3.45Å
271	S	83.9	Confident	85.4	Confident	32 Å²	32	72.8 Å²	72.8	22%	0.224	39%	0.387	C	S	.	.	H	α-helix	trans	-69.8	-43.9	177	-63.5	0	0	0	0	111.7	L266 N268 N273 R274 L275	L266-S271 WeakPolarHBondContact O-CB 3.07Å; N268-S271 PolarHBondContact O-N 3.15Å; S271-N273 PolarHBondContact O-N 3.12Å; S271-R274 PolarHBondContact O-N 3.48Å; S271-L275 PolarHBondContact O-N 3.38Å
272	S	82.8	Confident	85.7	Confident	24 Å²	24	71.6 Å²	71.6	17%	0.168	38%	0.383	C	S	.	.	H	α-helix	trans	-59.5	-44.7	175.2	175	0	0	0	0	111.5	N268 R274 L275 D276	N268-S272 PolarHBondContact O-N 3.08Å; S272-R274 VanDerWaalsContact C-N 3.34Å; S272-R274 PolarHBondContact O-N 3.18Å; S272-L275 WeakPolarHBondContact O-CB 3.03Å; S272-L275 PolarHBondContact O-N 2.9Å; S272-L275 VanDerWaalsContact O-N 3.12Å; S272-D276 PolarHBondContact O-N 2.87Å
273	N	83.6	Confident	86.2	Confident	39 Å²	39	66.7 Å²	66.7	21%	0.209	36%	0.36	C	S	.	.	H	α-helix	trans	-63	-38.5	177.2	-167.7	23.3	0	0	0	112.4	C269 S271 D276 Q277	C269-N273 VanDerWaalsContact O-CB 3.29Å; C269-N273 WeakPolarHBondContact O-CB 3.46Å; C269-N273 PolarHBondContact O-N 2.95Å; S271-N273 PolarHBondContact O-N 3.12Å; N273-D276 PolarHBondContact O-N 2.93Å; N273-Q277 WeakPolarHBondContact O-CG 3.37Å; N273-Q277 PolarHBondContact O-N 3.09Å; N273-Q277 VanDerWaalsContact O-N 3.09Å
274	R	86.6	Confident	86.4	Confident	187 Å²	187	59.3 Å²	59.3	71%	0.706	33%	0.329	S	S	*	.	H	α-helix	trans	-65.8	-38.6	173.3	-71.3	178.5	-170.6	-163.4	3.6	112.1	S270 S271 S272 Q277 A278	S270-R274 WeakPolarHBondContact O-CG 3.35Å; S270-R274 PolarHBondContact O-N 3.45Å; S271-R274 PolarHBondContact O-N 3.48Å; S272-R274 VanDerWaalsContact C-N 3.34Å; S272-R274 PolarHBondContact O-N 3.18Å; R274-Q277 PolarHBondContact O-N 3.42Å; R274-A278 WeakPolarHBondContact O-CB 3.25Å; R274-A278 PolarHBondContact O-N 3.35Å
275	L	86.9	Confident	86.9	Confident	16 Å²	16	57.7 Å²	57.7	8%	0.084	32%	0.324	C	S	.	.	H	α-helix	trans	-66	-38.6	176.2	-79.1	170.6	0	0	0	112.1	V254 L257 L266 S271 S272 A278 T279	V254-L275 HydrophobicContact CG1-CD2 4.47Å; L257-L275 HydrophobicContact CB-CD2 3.91Å; L257-L275 HydrophobicContact CD1-CD2 4.5Å; L266-L275 HydrophobicContact CB-CD1 4.01Å; L266-L275 HydrophobicContact CD1-CD1 3.98Å; S271-L275 PolarHBondContact O-N 3.38Å; S272-L275 WeakPolarHBondContact O-CB 3.03Å; S272-L275 PolarHBondContact O-N 2.9Å; S272-L275 VanDerWaalsContact O-N 3.12Å; L275-A278 PolarHBondContact O-N 2.91Å; L275-T279 WeakPolarHBondContact O-CB 3.46Å; L275-T279 PolarHBondContact O-N 3.44Å; L275-T279 PolarHBondContact O-OG1 2.9Å
276	D	84.4	Confident	87.5	Confident	36 Å²	36	55.4 Å²	55.4	19%	0.193	30%	0.301	C	S	.	.	H	α-helix	trans	-65.7	-42.6	175.3	-68.3	-46.8	0	0	0	111.7	K22 S272 N273 A278 T279 Q280	K22-D276 WeakPolarHBondContact CE-OD2 3.31Å; K22-D276 IonicContact NZ-OD1 3.73Å; K22-D276 IonicContact NZ-OD2 2.59Å; K22-D276 PolarHBondContact NZ-OD2 2.78Å; S272-D276 PolarHBondContact O-N 2.87Å; N273-D276 PolarHBondContact O-N 2.93Å; D276-A278 VanDerWaalsContact C-N 3.35Å; D276-T279 WeakPolarHBondContact O-CB 3.28Å; D276-T279 PolarHBondContact O-N 2.93Å; D276-Q280 PolarHBondContact O-N 3.22Å
277	Q	85.8	Confident	87.9	Confident	78 Å²	78	53.4 Å²	53.4	36%	0.364	29%	0.29	S	S	.	.	H	α-helix	trans	-59.1	-47.3	172.7	-72.4	174.5	9.2	0	0	111.3	V25 N273 R274 T279 Q280 V281	V25-Q277 HydrophobicContact CB-CG 4.28Å; V25-Q277 HydrophobicContact CG1-CG 3.82Å; V25-Q277 HydrophobicContact CG2-CG 3.41Å; V25-Q277 VanDerWaalsContact CG2-CG 3.41Å; N273-Q277 WeakPolarHBondContact O-CG 3.37Å; N273-Q277 PolarHBondContact O-N 3.09Å; N273-Q277 VanDerWaalsContact O-N 3.09Å; R274-Q277 PolarHBondContact O-N 3.42Å; Q277-T279 VanDerWaalsContact C-N 3.28Å; Q277-T279 PolarHBondContact O-N 3.43Å; Q277-Q280 PolarHBondContact O-N 3.43Å; Q277-V281 WeakPolarHBondContact O-CG2 3.29Å; Q277-V281 PolarHBondContact O-N 3.32Å
278	A	90.9	Very high	88.7	Confident	34 Å²	34	49.9 Å²	49.9	28%	0.281	27%	0.272	S	S	.	.	H	α-helix	trans	-61.3	-39.3	176.6	0	0	0	0	0	111.3	V254 R274 L275 D276 V281 T282	V254-A278 HydrophobicContact CG1-CB 3.91Å; V254-A278 HydrophobicContact CG2-CB 4.15Å; R274-A278 WeakPolarHBondContact O-CB 3.25Å; R274-A278 PolarHBondContact O-N 3.35Å; L275-A278 PolarHBondContact O-N 2.91Å; D276-A278 VanDerWaalsContact C-N 3.35Å; A278-V281 PolarHBondContact O-N 2.95Å; A278-T282 VanDerWaalsContact O-CB 3.31Å; A278-T282 WeakPolarHBondContact O-CB 3.23Å; A278-T282 VanDerWaalsContact O-CG2 3.27Å; A278-T282 WeakPolarHBondContact O-CG2 3.34Å; A278-T282 PolarHBondContact O-N 3.2Å; A278-T282 PolarHBondContact O-OG1 2.97Å
279	T	90.4	Very high	89.2	Confident	22 Å²	22	45.6 Å²	45.6	14%	0.135	25%	0.249	C	C	.	.	H	α-helix	trans	-61.7	-49.8	177.5	-57.7	0	0	0	0	109.7	Y251 V254 L275 D276 Q277 V281 T282 E283	Y251-T279 HydrophobicContact CE2-CG2 4.19Å; V254-T279 VanDerWaalsContact CG1-OG1 3.31Å; V254-T279 WeakPolarHBondContact CG1-OG1 3.32Å; L275-T279 WeakPolarHBondContact O-CB 3.46Å; L275-T279 PolarHBondContact O-N 3.44Å; L275-T279 PolarHBondContact O-OG1 2.9Å; D276-T279 WeakPolarHBondContact O-CB 3.28Å; D276-T279 PolarHBondContact O-N 2.93Å; Q277-T279 VanDerWaalsContact C-N 3.28Å; Q277-T279 PolarHBondContact O-N 3.43Å; T279-V281 PolarHBondContact O-N 3.24Å; T279-T282 PolarHBondContact O-N 3.48Å; T279-T282 PolarHBondContact O-OG1 2.81Å; T279-E283 WeakPolarHBondContact O-CB 3.39Å; T279-E283 PolarHBondContact O-N 2.86Å
280	Q	88.9	Confident	89.8	Confident	65 Å²	65	42.3 Å²	42.3	30%	0.304	23%	0.227	S	C	.	.	H	α-helix	trans	-60.7	-45	179.4	-172.9	65.1	59.6	0	0	112.4	D276 Q277 T284	D276-Q280 PolarHBondContact O-N 3.22Å; Q277-Q280 PolarHBondContact O-N 3.43Å; Q280-T284 VanDerWaalsContact O-CB 3.31Å; Q280-T284 WeakPolarHBondContact O-CB 3.43Å; Q280-T284 PolarHBondContact O-N 3.46Å; Q280-T284 PolarHBondContact O-OG1 2.99Å
281	V	91.6	Very high	90.2	Very high	101 Å²	101	39.4 Å²	39.4	61%	0.612	21%	0.207	S	C	*	.	H	α-helix	trans	-67.3	-46.1	-179.1	171.5	0	0	0	0	111	Q277 A278 T279 T284 L285	Q277-V281 WeakPolarHBondContact O-CG2 3.29Å; Q277-V281 PolarHBondContact O-N 3.32Å; A278-V281 PolarHBondContact O-N 2.95Å; T279-V281 PolarHBondContact O-N 3.24Å; V281-T284 WeakPolarHBondContact O-CB 3.34Å; V281-T284 PolarHBondContact O-N 3.24Å; V281-L285 PolarHBondContact O-N 3.47Å
282	T	95.1	Very high	90.7	Very high	18 Å²	18	39.5 Å²	39.5	11%	0.11	20%	0.204	C	C	.	.	H	α-helix	trans	-71.8	-33.6	-178.7	55.7	0	0	0	0	112.6	P250 Y251 V254 A278 T279 L285 G286	P250-T282 HydrophobicContact CB-CG2 3.61Å; Y251-T282 WeakPolarHBondContact CA-OG1 3.34Å; V254-T282 HydrophobicContact CG2-CG2 4.11Å; A278-T282 VanDerWaalsContact O-CB 3.31Å; A278-T282 WeakPolarHBondContact O-CB 3.23Å; A278-T282 VanDerWaalsContact O-CG2 3.27Å; A278-T282 WeakPolarHBondContact O-CG2 3.34Å; A278-T282 PolarHBondContact O-N 3.2Å; A278-T282 PolarHBondContact O-OG1 2.97Å; T279-T282 PolarHBondContact O-N 3.48Å; T279-T282 PolarHBondContact O-OG1 2.81Å; T282-L285 WeakPolarHBondContact O-CB 3.43Å; T282-L285 PolarHBondContact O-N 2.94Å; T282-G286 PolarHBondContact O-N 3.05Å
283	E	93.5	Very high	91	Very high	43 Å²	43	38.4 Å²	38.4	20%	0.201	20%	0.196	C	C	.	.	H	α-helix	trans	-63.7	-44.8	170.8	-176.6	172.4	-163	0	0	111	Y251 T279 L285 G286 M287	Y251-E283 HydrophobicContact CD2-CB 3.66Å; Y251-E283 HydrophobicContact CD2-CG 4.33Å; Y251-E283 HydrophobicContact CE2-CB 3.7Å; Y251-E283 HydrophobicContact CE2-CG 4.02Å; T279-E283 WeakPolarHBondContact O-CB 3.39Å; T279-E283 PolarHBondContact O-N 2.86Å; E283-L285 VanDerWaalsContact C-N 3.31Å; E283-L285 PolarHBondContact O-N 2.92Å; E283-G286 CarbonylContact O-C 3.35Å; E283-G286 WeakPolarHBondContact O-CA 3.37Å; E283-G286 PolarHBondContact O-N 2.87Å; E283-G286 VanDerWaalsContact O-N 3.12Å; E283-M287 HydrophobicContact CG-CE 4.29Å; E283-M287 WeakPolarHBondContact O-CG 3.17Å; E283-M287 PolarHBondContact O-N 3.46Å
284	T	92.9	Very high	91.3	Very high	15 Å²	15	37.2 Å²	37.2	9%	0.092	19%	0.191	C	C	.	.	H	α-helix	trans	-59.3	-43.2	176	-60.6	0	0	0	0	111.2	L33 L36 Y37 Q280 V281 M287 T288	L33-T284 HydrophobicContact CD2-CG2 3.52Å; L33-T284 VanDerWaalsContact CD2-OG1 3.25Å; L33-T284 WeakPolarHBondContact CD2-OG1 3.49Å; L36-T284 HydrophobicContact CD2-CG2 3.51Å; Y37-T284 HydrophobicContact CE1-CG2 3.94Å; Y37-T284 PolarHBondContact OH-OG1 3.36Å; Q280-T284 VanDerWaalsContact O-CB 3.31Å; Q280-T284 WeakPolarHBondContact O-CB 3.43Å; Q280-T284 PolarHBondContact O-N 3.46Å; Q280-T284 PolarHBondContact O-OG1 2.99Å; V281-T284 WeakPolarHBondContact O-CB 3.34Å; V281-T284 PolarHBondContact O-N 3.24Å; T284-M287 PolarHBondContact O-N 3.3Å; T284-T288 VanDerWaalsContact O-CG2 3.28Å; T284-T288 WeakPolarHBondContact O-CG2 3.49Å; T284-T288 PolarHBondContact O-N 2.8Å; T284-T288 VanDerWaalsContact O-N 3.15Å
285	L	95.4	Very high	91.4	Very high	64 Å²	64	32 Å²	32	34%	0.335	18%	0.176	S	C	.	.	H	α-helix	trans	-57.8	-51	172.6	179.8	65.3	0	0	0	110.6	F247 P250 V281 T282 E283 M287 T288	F247-L285 HydrophobicContact CD1-CD1 3.92Å; F247-L285 HydrophobicContact CD1-CG 4.24Å; F247-L285 VanDerWaalsContact CD1-O 3.31Å; F247-L285 WeakPolarHBondContact CD1-O 3.49Å; F247-L285 HydrophobicContact CE1-CD1 4.03Å; F247-L285 HydrophobicContact CG-CD1 4.4Å; F247-L285 HydrophobicContact CG-CG 4.46Å; P250-L285 HydrophobicContact CG-CD2 4.27Å; V281-L285 PolarHBondContact O-N 3.47Å; T282-L285 WeakPolarHBondContact O-CB 3.43Å; T282-L285 PolarHBondContact O-N 2.94Å; E283-L285 VanDerWaalsContact C-N 3.31Å; E283-L285 PolarHBondContact O-N 2.92Å; L285-M287 VanDerWaalsContact C-N 3.31Å; L285-M287 PolarHBondContact O-N 3.32Å; L285-T288 PolarHBondContact O-N 3.42Å; L285-T288 VanDerWaalsContact O-N 3.08Å; L285-T288 PolarHBondContact O-OG1 3.29Å
286	G	94.8	Very high	91.4	Very high	0 Å²	0	31.7 Å²	31.7	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-54.8	-43.5	175.4	0	0	0	0	0	113.1	W248 T282 E283 T288 H289	W248-G286 VanDerWaalsContact CZ2-O 3.23Å; W248-G286 WeakPolarHBondContact CZ2-O 3.34Å; T282-G286 PolarHBondContact O-N 3.05Å; E283-G286 CarbonylContact O-C 3.35Å; E283-G286 WeakPolarHBondContact O-CA 3.37Å; E283-G286 PolarHBondContact O-N 2.87Å; E283-G286 VanDerWaalsContact O-N 3.12Å; G286-T288 VanDerWaalsContact C-N 3.28Å; G286-T288 PolarHBondContact O-N 3.4Å; G286-H289 WeakPolarHBondContact O-CB 3.43Å; G286-H289 PolarHBondContact O-N 2.9Å
287	M	92.8	Very high	91.4	Very high	7 Å²	7	30.4 Å²	30.4	3%	0.034	17%	0.167	C	C	.	.	H	α-helix	trans	-60.4	-35.7	177.3	-73.6	-169.9	172.7	0	0	112.7	Y37 F79 W86 Y108 E283 T284 L285 H289 C290	Y37-M287 HydrophobicContact CE1-CB 4.22Å; Y37-M287 HydrophobicContact CE1-SD 3.7Å; Y37-M287 HydrophobicContact CE2-SD 3.88Å; Y37-M287 PolarHBondContact OH-SD 3.36Å; F79-M287 HydrophobicContact CE1-CB 4.14Å; F79-M287 HydrophobicContact CE1-CG 4.03Å; F79-M287 HydrophobicContact CZ-CB 4.4Å; F79-M287 HydrophobicContact CZ-CG 3.91Å; W86-M287 HydrophobicContact CG-CE 4.32Å; Y108-M287 HydrophobicContact CD2-CE 4.47Å; Y108-M287 HydrophobicContact CE2-CE 3.76Å; E283-M287 HydrophobicContact CG-CE 4.29Å; E283-M287 WeakPolarHBondContact O-CG 3.17Å; E283-M287 PolarHBondContact O-N 3.46Å; T284-M287 PolarHBondContact O-N 3.3Å; L285-M287 VanDerWaalsContact C-N 3.31Å; L285-M287 PolarHBondContact O-N 3.32Å; M287-H289 PolarHBondContact O-N 2.97Å; M287-C290 PolarHBondContact O-SG 3.43Å
288	T	94.8	Very high	91.2	Very high	22 Å²	22	28.2 Å²	28.2	14%	0.135	16%	0.162	C	C	.	.	H	α-helix	trans	-68.1	-18.3	177.9	69	0	0	0	0	113.5	L36 V40 F247 T284 L285 G286 C290 C291	L36-T288 HydrophobicContact CD2-CG2 4.5Å; V40-T288 HydrophobicContact CG2-CG2 3.74Å; F247-T288 WeakPolarHBondContact CD1-OG1 3.06Å; F247-T288 VanDerWaalsContact CE1-OG1 3.25Å; F247-T288 WeakPolarHBondContact CE1-OG1 3.49Å; T284-T288 VanDerWaalsContact O-CG2 3.28Å; T284-T288 WeakPolarHBondContact O-CG2 3.49Å; T284-T288 PolarHBondContact O-N 2.8Å; T284-T288 VanDerWaalsContact O-N 3.15Å; L285-T288 PolarHBondContact O-N 3.42Å; L285-T288 VanDerWaalsContact O-N 3.08Å; L285-T288 PolarHBondContact O-OG1 3.29Å; G286-T288 VanDerWaalsContact C-N 3.28Å; G286-T288 PolarHBondContact O-N 3.4Å; T288-C290 PolarHBondContact O-N 3.45Å; T288-C291 PolarHBondContact O-N 3.36Å; T288-C291 PolarHBondContact O-SG 2.93Å
289	H	95	Very high	90.5	Very high	8 Å²	8	34.8 Å²	34.8	4%	0.037	19%	0.185	C	C	.	.	G	3₁₀ helix	trans	-56.4	-34.7	-179.5	176.8	-95.4	0	0	0	113.5	Y244 F247 W248 G286 M287 C291 I292	Y244-H289 AromaticContact CD2-CE1 3.85Å; Y244-H289 AromaticContact CD2-NE2 3.93Å; F247-H289 HydrophobicContact CB-CB 3.94Å; F247-H289 HydrophobicContact CD1-CB 3.93Å; F247-H289 HydrophobicContact CG-CB 4.17Å; W248-H289 AromaticContact CD1-CG 3.88Å; W248-H289 AromaticContact NE1-CG 3.54Å; W248-H289 AromaticContact NE1-ND1 3.61Å; G286-H289 WeakPolarHBondContact O-CB 3.43Å; G286-H289 PolarHBondContact O-N 2.9Å; M287-H289 PolarHBondContact O-N 2.97Å; H289-C291 PolarHBondContact O-N 2.83Å; H289-C291 VanDerWaalsContact O-N 3.08Å; H289-I292 WeakPolarHBondContact O-CB 3.42Å; H289-I292 PolarHBondContact O-N 3.47Å
290	C	92.2	Very high	89.8	Confident	3 Å²	3	35.3 Å²	35.3	2%	0.02	19%	0.188	C	C	.	.	G	3₁₀ helix	trans	-61.4	-19.9	-175.4	64.3	0	0	0	0	114.2	N48 D76 F79 L80 M287 T288	N48-C290 PolarHBondContact ND2-O 2.92Å; D76-C290 HydrophobicContact CB-CB 4.4Å; F79-C290 HydrophobicContact CD1-CB 4Å; L80-C290 HydrophobicContact CD2-CB 4.5Å; L80-C290 WeakPolarHBondContact CD2-SG 3.38Å; L80-C290 HydrophobicContact CG-CB 4.2Å; M287-C290 PolarHBondContact O-SG 3.43Å; T288-C290 PolarHBondContact O-N 3.45Å
291	C	92.3	Very high	89	Confident	14 Å²	14	32.7 Å²	32.7	10%	0.095	18%	0.178	C	C	.	.	G	3₁₀ helix	trans	-95.9	-6.6	174.8	73	0	0	0	0	114	F43 G44 T288 H289	F43-C291 HydrophobicContact CB-CB 4.42Å; G44-C291 VanDerWaalsContact CA-CB 3.47Å; T288-C291 PolarHBondContact O-N 3.36Å; T288-C291 PolarHBondContact O-SG 2.93Å; H289-C291 PolarHBondContact O-N 2.83Å; H289-C291 VanDerWaalsContact O-N 3.08Å
292	I	93.3	Very high	88.2	Confident	34 Å²	34	31.3 Å²	31.3	17%	0.174	17%	0.165	C	C	.	.	H	α-helix	trans	-83	-30.4	-175.1	-54.2	-60.5	0	0	0	112.2	V243 F247 H289 I295 I296	V243-I292 HydrophobicContact CG1-CG2 3.71Å; F247-I292 HydrophobicContact CE1-CD1 4.24Å; F247-I292 HydrophobicContact CE1-CG1 3.81Å; F247-I292 HydrophobicContact CZ-CD1 4.14Å; F247-I292 HydrophobicContact CZ-CG1 3.88Å; H289-I292 WeakPolarHBondContact O-CB 3.42Å; H289-I292 PolarHBondContact O-N 3.47Å; I292-I295 HydrophobicContact CD1-CD1 4.23Å; I292-I295 WeakPolarHBondContact O-CA 3.49Å; I292-I295 VanDerWaalsContact O-CB 3.32Å; I292-I295 WeakPolarHBondContact O-CB 3.34Å; I292-I295 PolarHBondContact O-N 3.47Å; I292-I296 HydrophobicContact CG2-CD1 3.99Å; I292-I296 HydrophobicContact CG2-CG1 4.01Å; I292-I296 WeakPolarHBondContact O-CG1 3.15Å; I292-I296 PolarHBondContact O-N 3.05Å
293	N	89.8	Confident	87	Confident	0 Å²	0	36.8 Å²	36.8	0%	0	19%	0.187	C	C	.	.	H	α-helix	trans	-54.7	-50.4	-179.6	-76.4	-31.4	0	0	0	113.4	D76 I295 I296 Y297	D76-N293 PolarHBondContact OD2-ND2 3.29Å; N293-I295 VanDerWaalsContact C-N 3.29Å; N293-I295 PolarHBondContact O-N 2.99Å; N293-I296 PolarHBondContact O-N 3.38Å; N293-Y297 HydrophobicContact CB-CE2 4.24Å; N293-Y297 VanDerWaalsContact O-CD2 3.26Å; N293-Y297 WeakPolarHBondContact O-CD2 3.3Å; N293-Y297 VanDerWaalsContact O-CG 3.26Å; N293-Y297 PolarHBondContact O-N 3.49Å
294	P	89.3	Confident	86	Confident	14 Å²	14	35.6 Å²	35.6	9%	0.091	18%	0.182	C	C	.	.	H	α-helix	trans	-58.1	-37.6	173.7	-25.6	34.6	0	0	0	113.9	G47 V51 Y297 A298	G47-P294 VanDerWaalsContact C-CG 3.43Å; V51-P294 HydrophobicContact CG2-CB 4.07Å; V51-P294 HydrophobicContact CG2-CG 4.17Å; P294-Y297 PolarHBondContact O-N 3.36Å; P294-A298 PolarHBondContact O-N 2.84Å
295	I	89.3	Confident	85.3	Confident	77 Å²	77	41.3 Å²	41.3	40%	0.395	20%	0.201	S	C	.	.	H	α-helix	trans	-63.2	-47.7	177.5	-61.7	175.8	0	0	0	109.5	I292 N293 Y297 A298 F299	I292-I295 HydrophobicContact CD1-CD1 4.23Å; I292-I295 WeakPolarHBondContact O-CA 3.49Å; I292-I295 VanDerWaalsContact O-CB 3.32Å; I292-I295 WeakPolarHBondContact O-CB 3.34Å; I292-I295 PolarHBondContact O-N 3.47Å; N293-I295 VanDerWaalsContact C-N 3.29Å; N293-I295 PolarHBondContact O-N 2.99Å; I295-Y297 VanDerWaalsContact C-N 3.27Å; I295-Y297 PolarHBondContact O-N 3.35Å; I295-A298 PolarHBondContact O-N 2.74Å; I295-A298 VanDerWaalsContact O-N 3.14Å; I295-F299 HydrophobicContact CG2-CD2 3.64Å; I295-F299 HydrophobicContact CG2-CE2 3.77Å; I295-F299 VanDerWaalsContact O-CD2 3.24Å; I295-F299 WeakPolarHBondContact O-CD2 3.3Å; I295-F299 PolarHBondContact O-N 3.44Å
296	I	87.8	Confident	84.5	Confident	10 Å²	10	42.7 Å²	42.7	5%	0.051	21%	0.209	C	C	.	.	H	α-helix	trans	-56.5	-43.9	175.3	-63.9	169.9	0	0	0	110.4	L236 T239 I240 V243 I292 N293 A298 F299 V300	L236-I296 HydrophobicContact CD1-CG2 3.92Å; T239-I296 HydrophobicContact CG2-CG2 4.04Å; I240-I296 HydrophobicContact CG1-CD1 4.39Å; I240-I296 HydrophobicContact CG1-CG2 3.95Å; V243-I296 HydrophobicContact CB-CD1 3.92Å; V243-I296 HydrophobicContact CG1-CD1 3.97Å; V243-I296 HydrophobicContact CG2-CD1 3.98Å; I292-I296 HydrophobicContact CG2-CD1 3.99Å; I292-I296 HydrophobicContact CG2-CG1 4.01Å; I292-I296 WeakPolarHBondContact O-CG1 3.15Å; I292-I296 PolarHBondContact O-N 3.05Å; N293-I296 PolarHBondContact O-N 3.38Å; I296-A298 PolarHBondContact O-N 3.47Å; I296-F299 PolarHBondContact O-N 3.33Å; I296-V300 HydrophobicContact CG2-CB 4.27Å; I296-V300 HydrophobicContact CG2-CG2 4.09Å; I296-V300 WeakPolarHBondContact O-CA 3.3Å; I296-V300 VanDerWaalsContact O-CB 3.24Å; I296-V300 WeakPolarHBondContact O-CB 3.36Å; I296-V300 PolarHBondContact O-N 3.4Å
297	Y	84.2	Confident	83.7	Confident	9 Å²	9	46.6 Å²	46.6	4%	0.035	23%	0.225	C	C	.	.	H	α-helix	trans	-64.5	-38.9	178.9	-55.8	-31.5	0	0	0	112.9	V51 L69 L72 L236 I240 N293 P294 I295 G301	V51-Y297 HydrophobicContact CG1-CD2 4.27Å; V51-Y297 HydrophobicContact CG1-CE2 4.15Å; V51-Y297 HydrophobicContact CG2-CD2 3.72Å; V51-Y297 HydrophobicContact CG2-CE2 4.18Å; L69-Y297 HydrophobicContact CD2-CE1 3.98Å; L69-Y297 WeakPolarHBondContact CD2-OH 3.38Å; L72-Y297 WeakPolarHBondContact CD2-OH 3.44Å; L236-Y297 HydrophobicContact CD1-CD1 4.24Å; I240-Y297 HydrophobicContact CD1-CE1 3.63Å; I240-Y297 HydrophobicContact CG1-CE1 4.28Å; N293-Y297 HydrophobicContact CB-CE2 4.24Å; N293-Y297 VanDerWaalsContact O-CD2 3.26Å; N293-Y297 WeakPolarHBondContact O-CD2 3.3Å; N293-Y297 VanDerWaalsContact O-CG 3.26Å; N293-Y297 PolarHBondContact O-N 3.49Å; P294-Y297 PolarHBondContact O-N 3.36Å; I295-Y297 VanDerWaalsContact C-N 3.27Å; I295-Y297 PolarHBondContact O-N 3.35Å; Y297-G301 WeakPolarHBondContact O-CA 3.13Å; Y297-G301 PolarHBondContact O-N 3.19Å
298	A	80.6	Confident	83	Confident	33 Å²	33	48 Å²	48	27%	0.273	23%	0.232	S	C	.	.	H	α-helix	trans	-66.9	-41.1	178.9	0	0	0	0	0	112.8	P294 I295 I296	P294-A298 PolarHBondContact O-N 2.84Å; I295-A298 PolarHBondContact O-N 2.74Å; I295-A298 VanDerWaalsContact O-N 3.14Å; I296-A298 PolarHBondContact O-N 3.47Å
299	F	77.3	Confident	82.3	Confident	171 Å²	171	51.2 Å²	51.2	75%	0.75	25%	0.248	S	C	*	.	H	α-helix	trans	-90.4	-39	-175.4	-72	-74	0	0	0	113.8	I295 I296	I295-F299 HydrophobicContact CG2-CD2 3.64Å; I295-F299 HydrophobicContact CG2-CE2 3.77Å; I295-F299 VanDerWaalsContact O-CD2 3.24Å; I295-F299 WeakPolarHBondContact O-CD2 3.3Å; I295-F299 PolarHBondContact O-N 3.44Å; I296-F299 PolarHBondContact O-N 3.33Å
300	V	74.7	Confident	81.5	Confident	34 Å²	34	54.3 Å²	54.3	21%	0.206	27%	0.267	C	S	.	.	H	α-helix	trans	-96.3	-29	-174.8	-172.5	0	0	0	0	111.6	L236 T239 I296 E302	L236-V300 HydrophobicContact CB-CG1 4.39Å; L236-V300 HydrophobicContact CD1-CB 3.84Å; L236-V300 HydrophobicContact CD1-CG1 3.85Å; T239-V300 HydrophobicContact CG2-CG2 4.25Å; I296-V300 HydrophobicContact CG2-CB 4.27Å; I296-V300 HydrophobicContact CG2-CG2 4.09Å; I296-V300 WeakPolarHBondContact O-CA 3.3Å; I296-V300 VanDerWaalsContact O-CB 3.24Å; I296-V300 WeakPolarHBondContact O-CB 3.36Å; I296-V300 PolarHBondContact O-N 3.4Å; V300-E302 PolarHBondContact O-N 2.96Å
301	G	72.9	Confident	80.8	Confident	9 Å²	9	55.4 Å²	55.4	9%	0.093	27%	0.272	C	S	.	.			trans	-89.1	86.4	-175.7	0	0	0	0	0	113.8	Y297 K303 F304 R305	Y297-G301 WeakPolarHBondContact O-CA 3.13Å; Y297-G301 PolarHBondContact O-N 3.19Å; G301-K303 PolarHBondContact O-N 2.81Å; G301-K303 VanDerWaalsContact O-N 3.13Å; G301-F304 WeakPolarHBondContact O-CA 3.36Å; G301-F304 WeakPolarHBondContact O-CB 3.25Å; G301-F304 PolarHBondContact O-N 3.17Å; G301-R305 PolarHBondContact O-N 2.06Å
302	E	73.5	Confident	80.3	Confident	73 Å²	73	58.8 Å²	58.8	34%	0.341	29%	0.285	S	S	.	.	H	α-helix	trans	-51.2	-40.9	177.3	-69.4	173.7	-166.3	0	0	113.6	R232 V300 N306	R232-E302 WeakPolarHBondContact CD-OE2 3.47Å; R232-E302 IonicContact CZ-OE1 3.55Å; R232-E302 IonicContact CZ-OE2 3.54Å; R232-E302 VanDerWaalsContact CZ-OE2 3.24Å; R232-E302 IonicContact NE-OE1 2.64Å; R232-E302 IonicContact NE-OE2 3.26Å; R232-E302 IonicContact NH1-OE1 3.24Å; R232-E302 IonicContact NH1-OE2 3.74Å; R232-E302 PolarHBondContact NH1-OE2 3.49Å; V300-E302 PolarHBondContact O-N 2.96Å; E302-N306 PolarHBondContact O-N 2.89Å; E302-N306 VanDerWaalsContact O-N 3.17Å
303	K	71.3	Confident	79.5	Confident	132 Å²	132	63.2 Å²	63.2	57%	0.574	31%	0.305	S	S	*	.	H	α-helix	trans	-65.4	-42.7	176.8	-69.5	-173.8	-179.1	-178.5	0	111.8	G301 N306 Y307	G301-K303 PolarHBondContact O-N 2.81Å; G301-K303 VanDerWaalsContact O-N 3.13Å; K303-N306 PolarHBondContact O-N 2.91Å; K303-Y307 HydrophobicContact CB-CE2 4.39Å; K303-Y307 WeakPolarHBondContact O-CD2 3.36Å; K303-Y307 PolarHBondContact O-N 3.37Å
304	F	71.9	Confident	78.7	Confident	19 Å²	19	69.8 Å²	69.8	8%	0.083	33%	0.333	C	S	.	.	H	α-helix	trans	-65.2	-42.8	-179.1	-175.2	-95.5	0	0	0	110.4	V51 I54 G301 N306 Y307 L308	V51-F304 HydrophobicContact CB-CE2 4.4Å; V51-F304 HydrophobicContact CB-CZ 4.44Å; V51-F304 HydrophobicContact CG1-CE2 4.49Å; V51-F304 HydrophobicContact CG2-CE2 3.96Å; V51-F304 HydrophobicContact CG2-CZ 3.65Å; I54-F304 HydrophobicContact CB-CE2 4.15Å; I54-F304 HydrophobicContact CD1-CE1 4.27Å; I54-F304 HydrophobicContact CD1-CE2 3.74Å; I54-F304 HydrophobicContact CD1-CZ 3.6Å; I54-F304 HydrophobicContact CG2-CD2 4.16Å; I54-F304 HydrophobicContact CG2-CE2 3.97Å; G301-F304 WeakPolarHBondContact O-CA 3.36Å; G301-F304 WeakPolarHBondContact O-CB 3.25Å; G301-F304 PolarHBondContact O-N 3.17Å; F304-N306 VanDerWaalsContact C-N 3.33Å; F304-N306 PolarHBondContact O-N 3.27Å; F304-Y307 PolarHBondContact O-N 3.02Å; F304-Y307 VanDerWaalsContact O-N 3.15Å; F304-L308 HydrophobicContact CD1-CD1 4.45Å; F304-L308 HydrophobicContact CE1-CD1 3.84Å; F304-L308 WeakPolarHBondContact O-CB 3.27Å; F304-L308 PolarHBondContact O-N 3.02Å
305	R	78	Confident	77.8	Confident	134 Å²	134	73.3 Å²	73.3	51%	0.506	35%	0.349	S	S	.	.	H	α-helix	trans	-57	-43.4	173.8	-169.3	177.1	69.2	-173.5	3	112.7	G301 L308 L309	G301-R305 PolarHBondContact O-N 2.06Å; R305-L308 PolarHBondContact O-N 3.17Å; R305-L309 WeakPolarHBondContact O-CG 3.46Å; R305-L309 PolarHBondContact O-N 2.97Å
306	N	79.8	Confident	76.9	Confident	94 Å²	94	72.6 Å²	72.6	50%	0.503	35%	0.345	S	S	.	.	H	α-helix	trans	-64.9	-41.2	176.7	-71.7	-2.9	0	0	0	112.1	E302 K303 F304 L308 L309 V310	E302-N306 PolarHBondContact O-N 2.89Å; E302-N306 VanDerWaalsContact O-N 3.17Å; K303-N306 PolarHBondContact O-N 2.91Å; F304-N306 VanDerWaalsContact C-N 3.33Å; F304-N306 PolarHBondContact O-N 3.27Å; N306-L308 VanDerWaalsContact C-N 3.34Å; N306-L309 PolarHBondContact O-N 2.84Å; N306-V310 WeakPolarHBondContact O-CG2 3.4Å; N306-V310 PolarHBondContact O-N 3.32Å
307	Y	77.9	Confident	75.6	Confident	82 Å²	82	74.2 Å²	74.2	32%	0.322	36%	0.36	S	S	.	.	H	α-helix	trans	-66.6	-37.1	175.1	-72.2	-61.6	0	0	0	112.6	I54 C58 K59 K303 F304 V310 F311	I54-Y307 HydrophobicContact CG2-CG 4.35Å; C58-Y307 HydrophobicContact CB-CD1 3.69Å; C58-Y307 HydrophobicContact CB-CE1 4.3Å; C58-Y307 HydrophobicContact CB-CG 4.25Å; K59-Y307 HydrophobicContact CD-CD2 4.21Å; K59-Y307 HydrophobicContact CD-CE2 4.06Å; K59-Y307 HydrophobicContact CG-CD2 3.89Å; K59-Y307 HydrophobicContact CG-CE1 4.36Å; K59-Y307 HydrophobicContact CG-CE2 3.58Å; K59-Y307 HydrophobicContact CG-CG 4.44Å; K303-Y307 HydrophobicContact CB-CE2 4.39Å; K303-Y307 WeakPolarHBondContact O-CD2 3.36Å; K303-Y307 PolarHBondContact O-N 3.37Å; F304-Y307 PolarHBondContact O-N 3.02Å; F304-Y307 VanDerWaalsContact O-N 3.15Å; Y307-V310 PolarHBondContact O-N 3.31Å; Y307-F311 VanDerWaalsContact O-CB 3.28Å; Y307-F311 WeakPolarHBondContact O-CB 3.15Å; Y307-F311 PolarHBondContact O-N 2.9Å
308	L	77.5	Confident	74.3	Confident	37 Å²	37	81 Å²	81	19%	0.194	39%	0.389	C	S	.	.	H	α-helix	trans	-60.8	-50	174.4	-170.8	149.6	0	0	0	109.4	L50 I54 F304 R305 N306 V310 F311 F312	L50-L308 HydrophobicContact CD2-CD1 3.82Å; L50-L308 HydrophobicContact CD2-CG 4.36Å; I54-L308 HydrophobicContact CD1-CB 4.07Å; I54-L308 HydrophobicContact CD1-CG 4.42Å; F304-L308 HydrophobicContact CD1-CD1 4.45Å; F304-L308 HydrophobicContact CE1-CD1 3.84Å; F304-L308 WeakPolarHBondContact O-CB 3.27Å; F304-L308 PolarHBondContact O-N 3.02Å; R305-L308 PolarHBondContact O-N 3.17Å; N306-L308 VanDerWaalsContact C-N 3.34Å; L308-V310 PolarHBondContact O-N 3.09Å; L308-F311 WeakPolarHBondContact O-CB 3.2Å; L308-F311 PolarHBondContact O-N 2.76Å; L308-F311 VanDerWaalsContact O-N 3.1Å; L308-F312 HydrophobicContact CD1-CE2 4.45Å; L308-F312 HydrophobicContact CD2-CD2 3.39Å; L308-F312 HydrophobicContact CD2-CE2 3.35Å; L308-F312 HydrophobicContact CG-CD2 3.85Å; L308-F312 HydrophobicContact CG-CE2 3.71Å; L308-F312 VanDerWaalsContact O-CD2 3.26Å; L308-F312 WeakPolarHBondContact O-CD2 3.39Å; L308-F312 PolarHBondContact O-N 3.31Å
309	L	78.7	Confident	73.1	Confident	88 Å²	88	88.9 Å²	88.9	46%	0.461	41%	0.412	S	S	.	.	H	α-helix	trans	-56.1	-46.3	175	-72.5	169.8	0	0	0	112.9	R305 N306 F311 F312 Q313	R305-L309 WeakPolarHBondContact O-CG 3.46Å; R305-L309 PolarHBondContact O-N 2.97Å; N306-L309 PolarHBondContact O-N 2.84Å; L309-F311 VanDerWaalsContact C-N 3.33Å; L309-F311 PolarHBondContact O-N 3.16Å; L309-F312 PolarHBondContact O-N 2.85Å; L309-Q313 WeakPolarHBondContact O-CB 3.38Å; L309-Q313 VanDerWaalsContact O-CG 3.28Å; L309-Q313 WeakPolarHBondContact O-CG 3.2Å; L309-Q313 PolarHBondContact O-N 3.35Å
310	V	79.4	Confident	72	Confident	74 Å²	74	88 Å²	88	45%	0.448	41%	0.408	S	S	.	.	H	α-helix	trans	-63.4	-39.5	176.9	171.5	0	0	0	0	111.5	N306 Y307 L308 Q313 K314	N306-V310 WeakPolarHBondContact O-CG2 3.4Å; N306-V310 PolarHBondContact O-N 3.32Å; Y307-V310 PolarHBondContact O-N 3.31Å; L308-V310 PolarHBondContact O-N 3.09Å; V310-Q313 PolarHBondContact O-N 3.45Å; V310-K314 VanDerWaalsContact O-CB 3.22Å; V310-K314 WeakPolarHBondContact O-CB 3.43Å; V310-K314 PolarHBondContact O-N 3Å
311	F	77.9	Confident	70.8	Confident	26 Å²	26	89.9 Å²	89.9	11%	0.114	42%	0.422	C	S	.	.	H	α-helix	trans	-63.8	-47.4	176.5	-179.1	-92.4	0	0	0	111.2	L50 L53 Y307 L308 L309 Q313 K314 H315	L50-F311 HydrophobicContact CD1-CD1 3.89Å; L50-F311 HydrophobicContact CD1-CE1 3.76Å; L50-F311 HydrophobicContact CD1-CZ 4.43Å; L53-F311 HydrophobicContact CD1-CZ 4.39Å; Y307-F311 VanDerWaalsContact O-CB 3.28Å; Y307-F311 WeakPolarHBondContact O-CB 3.15Å; Y307-F311 PolarHBondContact O-N 2.9Å; L308-F311 WeakPolarHBondContact O-CB 3.2Å; L308-F311 PolarHBondContact O-N 2.76Å; L308-F311 VanDerWaalsContact O-N 3.1Å; L309-F311 VanDerWaalsContact C-N 3.33Å; L309-F311 PolarHBondContact O-N 3.16Å; F311-Q313 PolarHBondContact O-N 2.74Å; F311-K314 PolarHBondContact O-N 3.5Å; F311-H315 AromaticContact CD2-CD2 3.64Å; F311-H315 AromaticContact CE2-CD2 3.71Å; F311-H315 HydrophobicContact CZ-CB 4.41Å; F311-H315 WeakPolarHBondContact O-CB 3.27Å; F311-H315 PolarHBondContact O-N 3.23Å
312	F	80.4	Confident	69.5	Low	84 Å²	84	98.3 Å²	98.3	37%	0.368	46%	0.456	S	S	.	.	I	π-helix	trans	-59.4	-45.8	174.8	-87.8	-87.8	0	0	0	111.2	L308 L309 K314 I316 A317	L308-F312 HydrophobicContact CD1-CE2 4.45Å; L308-F312 HydrophobicContact CD2-CD2 3.39Å; L308-F312 HydrophobicContact CD2-CE2 3.35Å; L308-F312 HydrophobicContact CG-CD2 3.85Å; L308-F312 HydrophobicContact CG-CE2 3.71Å; L308-F312 VanDerWaalsContact O-CD2 3.26Å; L308-F312 WeakPolarHBondContact O-CD2 3.39Å; L308-F312 PolarHBondContact O-N 3.31Å; L309-F312 PolarHBondContact O-N 2.85Å; F312-K314 PolarHBondContact O-N 3.41Å; F312-I316 HydrophobicContact CD1-CB 4.13Å; F312-I316 HydrophobicContact CD1-CD1 3.29Å; F312-I316 HydrophobicContact CD1-CG1 4.25Å; F312-I316 HydrophobicContact CD1-CG2 4.25Å; F312-I316 HydrophobicContact CE1-CD1 3.33Å; F312-I316 HydrophobicContact CG-CD1 4Å; F312-I316 HydrophobicContact CZ-CD1 4.07Å; F312-I316 CarbonylContact O-C 3.56Å; F312-I316 WeakPolarHBondContact O-CA 3.27Å; F312-I316 WeakPolarHBondContact O-CB 3.37Å; F312-I316 PolarHBondContact O-N 3.35Å; F312-A317 PolarHBondContact O-N 3.23Å
313	Q	77.3	Confident	68.1	Low	128 Å²	128	100.3 Å²	100.3	60%	0.598	48%	0.477	S	S	*	.	I	π-helix	trans	-61.7	-44.9	177.1	-74	171.5	-9.1	0	0	112.5	L309 V310 F311 K318	L309-Q313 WeakPolarHBondContact O-CB 3.38Å; L309-Q313 VanDerWaalsContact O-CG 3.28Å; L309-Q313 WeakPolarHBondContact O-CG 3.2Å; L309-Q313 PolarHBondContact O-N 3.35Å; V310-Q313 PolarHBondContact O-N 3.45Å; F311-Q313 PolarHBondContact O-N 2.74Å; Q313-K318 PolarHBondContact O-N 3.22Å
314	K	72.7	Confident	66.7	Low	137 Å²	137	97.9 Å²	97.9	60%	0.596	48%	0.476	S	S	*	.	I	π-helix	trans	-76.1	-38.6	-174	-170.4	179.2	-177.2	-173.7	0	113.6	V310 F311 F312 K318	V310-K314 VanDerWaalsContact O-CB 3.22Å; V310-K314 WeakPolarHBondContact O-CB 3.43Å; V310-K314 PolarHBondContact O-N 3Å; F311-K314 PolarHBondContact O-N 3.5Å; F312-K314 PolarHBondContact O-N 3.41Å; K314-K318 VanDerWaalsContact O-CB 3.31Å; K314-K318 WeakPolarHBondContact O-CB 3.3Å
315	H	71	Confident	64.9	Low	89 Å²	89	102.5 Å²	102.5	41%	0.412	51%	0.51	S	S	.	.	I	π-helix	trans	-109.4	-29.3	-170.1	-69.8	-79.8	0	0	0	114.1	F311 R319	F311-H315 AromaticContact CD2-CD2 3.64Å; F311-H315 AromaticContact CE2-CD2 3.71Å; F311-H315 HydrophobicContact CZ-CB 4.41Å; F311-H315 WeakPolarHBondContact O-CB 3.27Å; F311-H315 PolarHBondContact O-N 3.23Å; H315-R319 WeakPolarHBondContact O-CB 3.36Å
316	I	69.3	Low	63.2	Low	61 Å²	61	103.2 Å²	103.2	31%	0.313	52%	0.523	S	S	.	.	I	π-helix	trans	-102.1	-58	-176.5	-64.5	169.4	0	0	0	109	F312 K318 R319 F320	F312-I316 HydrophobicContact CD1-CB 4.13Å; F312-I316 HydrophobicContact CD1-CD1 3.29Å; F312-I316 HydrophobicContact CD1-CG1 4.25Å; F312-I316 HydrophobicContact CD1-CG2 4.25Å; F312-I316 HydrophobicContact CE1-CD1 3.33Å; F312-I316 HydrophobicContact CG-CD1 4Å; F312-I316 HydrophobicContact CZ-CD1 4.07Å; F312-I316 CarbonylContact O-C 3.56Å; F312-I316 WeakPolarHBondContact O-CA 3.27Å; F312-I316 WeakPolarHBondContact O-CB 3.37Å; F312-I316 PolarHBondContact O-N 3.35Å; I316-K318 VanDerWaalsContact C-N 3.33Å; I316-K318 PolarHBondContact O-N 2.98Å; I316-R319 PolarHBondContact O-N 2.91Å; I316-F320 HydrophobicContact CG2-CD2 3.72Å; I316-F320 HydrophobicContact CG2-CE2 3.9Å; I316-F320 WeakPolarHBondContact O-CD2 3.4Å; I316-F320 PolarHBondContact O-N 3.36Å
317	A	62	Low	61.2	Low	44 Å²	44	107.4 Å²	107.4	36%	0.364	54%	0.537	S	S	.	.	I	π-helix	trans	-62.3	-37.5	179.4	0	0	0	0	0	112.5	F312 R319 F320 C321	F312-A317 PolarHBondContact O-N 3.23Å; A317-R319 VanDerWaalsContact C-N 3.34Å; A317-R319 PolarHBondContact O-N 3.42Å; A317-F320 PolarHBondContact O-N 2.89Å; A317-C321 WeakPolarHBondContact O-CB 3.49Å; A317-C321 PolarHBondContact O-N 3.39Å; A317-C321 PolarHBondContact O-SG 3.28Å; A317-C321 VanDerWaalsContact O-SG 3.35Å
318	K	56.3	Low	59.4	Low	152 Å²	152	112.4 Å²	112.4	66%	0.661	56%	0.563	S	S	*	*	H	α-helix	trans	-70.3	-26.1	175	-154.5	174.2	-175.6	176.2	0	113.7	Q313 K314 I316 K322	Q313-K318 PolarHBondContact O-N 3.22Å; K314-K318 VanDerWaalsContact O-CB 3.31Å; K314-K318 WeakPolarHBondContact O-CB 3.3Å; I316-K318 VanDerWaalsContact C-N 3.33Å; I316-K318 PolarHBondContact O-N 2.98Å; K318-K322 PolarHBondContact O-N 3.35Å
319	R	56.3	Low	57.4	Low	199 Å²	199	119.4 Å²	119.4	75%	0.751	60%	0.595	S	S	*	*	H	α-helix	trans	-79	-41.2	172.3	-102.3	-178.6	169.5	179	-3.4	111.6	H315 I316 A317 K322	H315-R319 WeakPolarHBondContact O-CB 3.36Å; I316-R319 PolarHBondContact O-N 2.91Å; A317-R319 VanDerWaalsContact C-N 3.34Å; A317-R319 PolarHBondContact O-N 3.42Å; R319-K322 WeakPolarHBondContact O-CB 3.4Å; R319-K322 PolarHBondContact O-N 3.49Å
320	F	53.8	Low	55.4	Low	152 Å²	152	123.7 Å²	123.7	67%	0.667	61%	0.612	S	S	*	*	H	α-helix	trans	-71.7	-35.9	175.5	-84.5	-82.4	0	0	0	112.4	I316 A317 K322 C323 C324	I316-F320 HydrophobicContact CG2-CD2 3.72Å; I316-F320 HydrophobicContact CG2-CE2 3.9Å; I316-F320 WeakPolarHBondContact O-CD2 3.4Å; I316-F320 PolarHBondContact O-N 3.36Å; A317-F320 PolarHBondContact O-N 2.89Å; F320-K322 VanDerWaalsContact C-N 3.27Å; F320-K322 PolarHBondContact O-N 3.07Å; F320-C323 WeakPolarHBondContact O-CA 3.5Å; F320-C323 WeakPolarHBondContact O-CB 3.36Å; F320-C323 PolarHBondContact O-N 3.23Å; F320-C324 PolarHBondContact O-N 3.45Å
321	C	48.4	Very low	53.2	Low	74 Å²	74	124.5 Å²	124.5	50%	0.5	63%	0.627	S	S	.	*	G	3₁₀ helix	trans	-69.2	-20.6	170.3	-77	0	0	0	0	113.1	A317 C323 C324	A317-C321 WeakPolarHBondContact O-CB 3.49Å; A317-C321 PolarHBondContact O-N 3.39Å; A317-C321 PolarHBondContact O-SG 3.28Å; A317-C321 VanDerWaalsContact O-SG 3.35Å; C321-C323 PolarHBondContact O-N 3.19Å; C321-C324 CarbonylContact O-C 3.49Å; C321-C324 PolarHBondContact O-N 2.83Å
322	K	45.5	Very low	51.3	Low	186 Å²	186	129 Å²	129	81%	0.809	66%	0.659	S	S	*	*	G	3₁₀ helix	trans	-69.5	-20.2	167.1	-98.2	-171.8	174.2	-168.3	0	112.7	K318 R319 F320	K318-K322 PolarHBondContact O-N 3.35Å; R319-K322 WeakPolarHBondContact O-CB 3.4Å; R319-K322 PolarHBondContact O-N 3.49Å; F320-K322 VanDerWaalsContact C-N 3.27Å; F320-K322 PolarHBondContact O-N 3.07Å
323	C	45.7	Very low	49.1	Very low	114 Å²	114	134 Å²	134	77%	0.77	68%	0.684	S	S	*	*	G	3₁₀ helix	trans	-92.6	-3.5	170.6	-78.5	0	0	0	0	113.6	F320 C321	F320-C323 WeakPolarHBondContact O-CA 3.5Å; F320-C323 WeakPolarHBondContact O-CB 3.36Å; F320-C323 PolarHBondContact O-N 3.23Å; C321-C323 PolarHBondContact O-N 3.19Å
324	C	40.4	Very low	47.2	Very low	82 Å²	82	139.8 Å²	139.8	55%	0.554	70%	0.7	S	S	*	*			trans	-121.2	95.5	173.6	-71.9	0	0	0	0	109.9	F320 C321 I326	F320-C324 PolarHBondContact O-N 3.45Å; C321-C324 CarbonylContact O-C 3.49Å; C321-C324 PolarHBondContact O-N 2.83Å; C324-I326 PolarHBondContact O-N 2.98Å
325	S	34.2	Very low	45.4	Very low	116 Å²	116	137.3 Å²	137.3	81%	0.811	71%	0.705	S	S	*	*	T	Hydrogen-bonded Turn	trans	-70.2	35.7	174.5	60	0	0	0	0	113.9
326	I	43.8	Very low	43.9	Very low	148 Å²	148	139.1 Å²	139.1	76%	0.759	73%	0.727	S	S	*	*	T	Hydrogen-bonded Turn	trans	-119.2	-13	-175.8	-66.1	-178.1	0	0	0	112.7	C324	C324-I326 PolarHBondContact O-N 2.98Å
327	F	36.7	Very low	42.5	Very low	183 Å²	183	141 Å²	141	80%	0.803	75%	0.746	S	S	*	*			trans	-112.7	27.2	179.1	-118.2	-84.9	0	0	0	114.6	Q329	F327-Q329 VanDerWaalsContact C-N 3.3Å; F327-Q329 PolarHBondContact O-N 3.29Å
328	Q	39.5	Very low	41.3	Very low	187 Å²	187	145.3 Å²	145.3	87%	0.874	77%	0.767	S	S	*	*			trans	-96.8	61.8	167.2	-157.8	170.7	-7.2	0	0	108.5
329	Q	35.9	Very low	40.2	Very low	184 Å²	184	149 Å²	149	86%	0.86	78%	0.779	S	S	*	*			trans	-105.7	117.9	161.4	-152.7	165	12.9	0	0	107.4	F327	F327-Q329 VanDerWaalsContact C-N 3.3Å; F327-Q329 PolarHBondContact O-N 3.29Å
330	E	37.3	Very low	39.2	Very low	177 Å²	177	145.3 Å²	145.3	83%	0.827	78%	0.779	S	S	*	*	P	Polyproline II helix	trans	-49.1	136	-173.6	-66.3	162.1	148.1	0	0	112.1	P332	E330-P332 WeakPolarHBondContact O-CD 3.35Å
331	A	33	Very low	38.2	Very low	92 Å²	92	148.3 Å²	148.3	76%	0.76	79%	0.785	S	S	*	*	P	Polyproline II helix	trans	-70.4	121.8	158.2	0	0	0	0	0	107	E333	A331-E333 PolarHBondContact O-N 3.39Å
332	P	37	Very low	37.4	Very low	120 Å²	120	150.3 Å²	150.3	78%	0.779	80%	0.8	S	S	*	*	P	Polyproline II helix	trans	-69.7	125.5	174.8	27	-29.4	0	0	0	108.6	E330 R334	E330-P332 WeakPolarHBondContact O-CD 3.35Å; P332-R334 PolarHBondContact O-N 3.35Å
333	E	35.9	Very low	37	Very low	190 Å²	190	147.2 Å²	147.2	89%	0.888	80%	0.797	S	S	*	*	P	Polyproline II helix	trans	-52	118.7	169.1	-67.3	-178.7	154.8	0	0	109.2	A331 A335	A331-E333 PolarHBondContact O-N 3.39Å; E333-A335 PolarHBondContact O-N 3.44Å
334	R	35.8	Very low	36.4	Very low	249 Å²	249	145.2 Å²	145.2	94%	0.94	80%	0.796	S	S	*	*			trans	-71.4	88.5	164.4	-87.6	-176.5	177.2	171.6	-0.9	108	P332 S336	P332-R334 PolarHBondContact O-N 3.35Å; R334-S336 PolarHBondContact O-N 3.45Å
335	A	35.4	Very low	36.1	Very low	85 Å²	85	150.8 Å²	150.8	70%	0.702	81%	0.814	S	S	*	*			trans	-61.5	109.5	159	0	0	0	0	0	108.3	E333 S337	E333-A335 PolarHBondContact O-N 3.44Å; A335-S337 PolarHBondContact O-N 3.33Å; A335-S337 VanDerWaalsContact O-N 3.15Å
336	S	38.6	Very low	36.1	Very low	126 Å²	126	154.5 Å²	154.5	88%	0.881	82%	0.819	S	S	*	*			trans	-77.3	90.2	166.7	54.3	0	0	0	0	108.7	R334	R334-S336 PolarHBondContact O-N 3.45Å
337	S	40.7	Very low	35.9	Very low	100 Å²	100	156.4 Å²	156.4	70%	0.699	82%	0.824	S	S	*	*			trans	-125.1	100	166.3	63.1	0	0	0	0	109.6	A335	A335-S337 PolarHBondContact O-N 3.33Å; A335-S337 VanDerWaalsContact O-N 3.15Å
338	V	37.2	Very low	35.8	Very low	135 Å²	135	155.7 Å²	155.7	82%	0.818	83%	0.827	S	S	*	*			trans	-137.7	92.2	153.8	-176.5	0	0	0	0	106.9
339	Y	33.4	Very low	35.7	Very low	229 Å²	229	151.6 Å²	151.6	90%	0.898	82%	0.819	S	S	*	*			trans	-93.6	105.6	164	-152.5	-86.5	0	0	0	105.5
340	T	34.1	Very low	35.8	Very low	123 Å²	123	149.9 Å²	149.9	76%	0.755	82%	0.821	S	S	*	*			trans	-91.6	107.1	174.7	-37.7	0	0	0	0	108.3
341	R	33.1	Very low	35.9	Very low	214 Å²	214	144.3 Å²	144.3	81%	0.808	81%	0.811	S	S	*	*			trans	-84.5	115.1	170.3	-173.3	178.4	-176	166.3	-0.1	107.7
342	S	31.6	Very low	36	Very low	116 Å²	116	152.1 Å²	152.1	81%	0.811	84%	0.839	S	S	*	*			trans	-105.9	115	166.5	174.5	0	0	0	0	108.2
343	T	38.5	Very low	36	Very low	122 Å²	122	153.8 Å²	153.8	75%	0.748	84%	0.842	S	S	*	*			trans	-95.5	130.2	161.7	36.9	0	0	0	0	107.8
344	G	32	Very low	36	Very low	72 Å²	72	151.8 Å²	151.8	74%	0.742	84%	0.839	S	S	*	*			trans	-168.8	86.5	172.6	0	0	0	0	0	108.7
345	E	34.5	Very low	36	Very low	198 Å²	198	146.4 Å²	146.4	93%	0.925	83%	0.834	S	S	*	*			trans	-59.2	136.9	165.7	-71.9	164.5	139.2	0	0	110.1
346	Q	35	Very low	36	Very low	195 Å²	195	150.1 Å²	150.1	91%	0.911	84%	0.841	S	S	*	*			trans	-153	111.5	148.8	-114	173	-5.4	0	0	109.1
347	E	37.6	Very low	35.9	Very low	187 Å²	187	151.6 Å²	151.6	87%	0.874	84%	0.839	S	S	*	*			trans	-57.8	135.7	164.4	-62.3	173.4	135.3	0	0	110.7
348	I	36.4	Very low	35.5	Very low	169 Å²	169	155 Å²	155	87%	0.867	85%	0.848	S	S	*	*			trans	-146.3	116.4	142.2	-63.6	-170	0	0	0	108.8
349	S	36.8	Very low	35.4	Very low	100 Å²	100	156.4 Å²	156.4	70%	0.699	85%	0.85	S	S	*	*			trans	-71.5	173.8	167.2	-63.7	0	0	0	0	112.9
350	V	37.6	Very low	35.6	Very low	148 Å²	148	150.8 Å²	150.8	90%	0.897	85%	0.847	S	S	*	*			trans	101.2	116.3	171	-165.6	0	0	0	0	110.8
351	G	39.8	Very low	35.7	Very low	61 Å²	61	153.2 Å²	153.2	63%	0.629	85%	0.854	S	S	*	*			cis	120.3	91.1	23.8	0	0	0	0	0	108.3
352	L	35.5	Very low	35.9	Very low	256 Å²	256	147.6 Å²	147.6	100%	1.34	86%	0.859	S	S	*	*			trans	176.6	0	132.2	-119.2	107.6	0	0	0	109.9

Retrieved 352 of 352 residues in 522.8 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).