A0A089H976_HUMAN Loading...

C-C chemokine receptor type 5

Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Participates in T-lymphocyte migration to the infection site by acting as a chemotactic receptor.

AlphaFold DB , UniProt , Accession A0A089H976, Species HUMAN (Homo sapiens, Human), Gene CCR5, Length 352 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	40.4	Very low	39.2	Very low	218 Å²	218	152.1 Å²	152.1	100%	1.074	79%	0.786	S	S	*	*				0	91.9	0	-80.6	-175.6	-178.7	0	0	105.7	Y3	M1-Y3 PolarHBondContact O-N 3.31Å
2	D	34.6	Very low	39.6	Very low	163 Å²	163	152 Å²	152	87%	0.872	79%	0.785	S	S	*	*			trans	-80	111.1	-174.1	-63	-34.7	0	0	0	109.4	Q4	D2-Q4 PolarHBondContact O-N 2.98Å
3	Y	40.6	Very low	39.5	Very low	216 Å²	216	148.2 Å²	148.2	85%	0.847	77%	0.767	S	S	*	*			trans	-81	103.6	167.8	-80.1	-91.4	0	0	0	108.5	M1	M1-Y3 PolarHBondContact O-N 3.31Å
4	Q	35	Very low	39.5	Very low	185 Å²	185	152.6 Å²	152.6	86%	0.864	77%	0.771	S	S	*	*			trans	-92.4	99.7	162	-85.3	178.2	-41.6	0	0	109.2	D2	D2-Q4 PolarHBondContact O-N 2.98Å
5	V	48.7	Very low	39.4	Very low	142 Å²	142	158.3 Å²	158.3	86%	0.861	78%	0.782	S	S	*	*			trans	-94	103	156.7	177.9	0	0	0	0	106.2
6	S	37.2	Very low	39.4	Very low	105 Å²	105	156.3 Å²	156.3	73%	0.734	78%	0.781	S	S	*	*			trans	-112.5	115.8	179.2	117.9	0	0	0	0	110.9
7	S	42.3	Very low	39.7	Very low	97 Å²	97	152.7 Å²	152.7	68%	0.678	77%	0.774	S	S	*	*			trans	69.2	129.4	160.2	-156.9	0	0	0	0	120.1	I9	S7-I9 PolarHBondContact O-N 3.26Å
8	P	40.1	Very low	40.2	Very low	91 Å²	91	149.1 Å²	149.1	59%	0.591	75%	0.754	S	S	*	*			trans	-84.4	97.6	169.7	35	-27.5	0	0	0	109.2	Y10	P8-Y10 VanDerWaalsContact C-N 3.31Å; P8-Y10 HydrophobicContact CB-CD2 3.94Å; P8-Y10 HydrophobicContact CB-CE2 3.6Å; P8-Y10 HydrophobicContact CG-CD2 4.38Å; P8-Y10 HydrophobicContact CG-CE2 3.93Å; P8-Y10 PolarHBondContact O-N 3.06Å; P8-Y10 VanDerWaalsContact O-N 3.13Å
9	I	37.1	Very low	40.8	Very low	140 Å²	140	145.6 Å²	145.6	72%	0.718	74%	0.743	S	S	*	*			trans	-73.8	97	155.3	-62.6	175.9	0	0	0	105.1	S7 D11	S7-I9 PolarHBondContact O-N 3.26Å; I9-D11 PolarHBondContact O-N 3.41Å
10	Y	39.4	Very low	41.1	Very low	198 Å²	198	142.4 Å²	142.4	78%	0.776	73%	0.734	S	S	*	*			trans	-70.7	87.8	166.5	-73.3	-78.7	0	0	0	107.8	P8 I12	P8-Y10 VanDerWaalsContact C-N 3.31Å; P8-Y10 HydrophobicContact CB-CD2 3.94Å; P8-Y10 HydrophobicContact CB-CE2 3.6Å; P8-Y10 HydrophobicContact CG-CD2 4.38Å; P8-Y10 HydrophobicContact CG-CE2 3.93Å; P8-Y10 PolarHBondContact O-N 3.06Å; P8-Y10 VanDerWaalsContact O-N 3.13Å; Y10-I12 PolarHBondContact O-N 3.34Å
11	D	35.8	Very low	41.6	Very low	118 Å²	118	139.7 Å²	139.7	63%	0.631	72%	0.718	S	S	*	*			trans	-62.5	102.1	161.8	-89.7	-21.7	0	0	0	107.5	I9 N13	I9-D11 PolarHBondContact O-N 3.41Å; D11-N13 HydrophobicContact CB-CB 4.45Å; D11-N13 PolarHBondContact O-N 3.49Å
12	I	43.8	Very low	42.5	Very low	151 Å²	151	134.1 Å²	134.1	77%	0.774	69%	0.688	S	S	*	*			trans	-74.5	62.9	164.9	-51.8	176.3	0	0	0	107.1	Y10	Y10-I12 PolarHBondContact O-N 3.34Å
13	N	39.2	Very low	43.9	Very low	102 Å²	102	130.6 Å²	130.6	55%	0.545	67%	0.668	S	S	.	*			trans	-102.9	94.9	170.5	-76.4	-37.8	0	0	0	106.8	D11 Y15	D11-N13 HydrophobicContact CB-CB 4.45Å; D11-N13 PolarHBondContact O-N 3.49Å; N13-Y15 PolarHBondContact O-N 3.11Å
14	Y	39	Very low	45.3	Very low	211 Å²	211	124.9 Å²	124.9	83%	0.827	65%	0.653	S	S	*	*			trans	-53.7	122.5	161	-99.1	-95.7	0	0	0	107.7	T16	Y14-T16 VanDerWaalsContact C-N 3.26Å; Y14-T16 PolarHBondContact O-N 3.14Å
15	Y	37.3	Very low	47	Very low	238 Å²	238	118.1 Å²	118.1	93%	0.933	62%	0.623	S	S	*	*	S	Bend	trans	-55.4	83.3	178.1	-100.8	-100.7	0	0	0	111.4	N13	N13-Y15 PolarHBondContact O-N 3.11Å
16	T	40	Very low	48.2	Very low	125 Å²	125	117.1 Å²	117.1	77%	0.767	61%	0.608	S	S	*	*			trans	-159.8	133.5	159.4	21.2	0	0	0	0	107.8	Y14	Y14-T16 VanDerWaalsContact C-N 3.26Å; Y14-T16 PolarHBondContact O-N 3.14Å
17	S	44.6	Very low	50.3	Low	96 Å²	96	117 Å²	117	67%	0.671	60%	0.596	S	S	*	*	S	Bend	trans	-65.3	152.2	-162.3	8	0	0	0	0	116.7
18	E	48.6	Very low	52.2	Low	87 Å²	87	117.9 Å²	117.9	41%	0.407	59%	0.591	S	S	.	*			trans	85	59.1	160.9	-62.1	-176.8	179.5	0	0	122.2
19	P	51.1	Low	54.2	Low	83 Å²	83	114.4 Å²	114.4	54%	0.539	57%	0.571	S	S	.	*	H	α-helix	trans	-69.7	-30.3	160.5	-15.9	29.6	0	0	0	113.9	Q21 I23	P19-Q21 PolarHBondContact O-N 3.47Å; P19-I23 WeakPolarHBondContact O-CD1 3.29Å; P19-I23 WeakPolarHBondContact O-CG1 3.45Å
20	S	47.8	Very low	56.5	Low	82 Å²	82	109.1 Å²	109.1	57%	0.573	55%	0.548	S	S	*	.	H	α-helix	trans	-68.2	-34.8	-167.7	55.7	0	0	0	0	114.3
21	Q	52	Low	58.9	Low	85 Å²	85	109.5 Å²	109.5	40%	0.397	55%	0.548	S	S	.	.	H	α-helix	trans	-76.8	-33.6	-177.3	-160.4	176.4	15	0	0	112.6	P19 I23 N24 V25 N273	P19-Q21 PolarHBondContact O-N 3.47Å; Q21-I23 VanDerWaalsContact C-N 3.31Å; Q21-I23 PolarHBondContact O-N 3.5Å; Q21-N24 PolarHBondContact O-N 3.49Å; Q21-V25 WeakPolarHBondContact O-CG2 3.48Å; Q21-V25 PolarHBondContact O-N 2.9Å; Q21-N273 VanDerWaalsContact CD-ND2 3.31Å; Q21-N273 WeakPolarHBondContact CG-ND2 3.3Å; Q21-N273 PolarHBondContact OE1-ND2 3.45Å
22	K	58.9	Low	61.5	Low	101 Å²	101	109 Å²	109	44%	0.439	55%	0.545	S	S	.	.	H	α-helix	trans	-67.1	-32.3	175.8	-69	-165.1	-178.9	-149.7	0	112.3	K26 N273 D276	K22-K26 PolarHBondContact O-N 2.95Å; K22-N273 WeakPolarHBondContact CG-OD1 3.42Å; K22-D276 IonicContact NZ-OD2 2.88Å; K22-D276 PolarHBondContact NZ-OD2 3.15Å
23	I	63	Low	63.7	Low	90 Å²	90	102.2 Å²	102.2	46%	0.462	51%	0.51	S	S	.	.	H	α-helix	trans	-64	-44.4	177.4	-65.4	166	0	0	0	111.1	P19 Q21 V25 K26 Q27	P19-I23 WeakPolarHBondContact O-CD1 3.29Å; P19-I23 WeakPolarHBondContact O-CG1 3.45Å; Q21-I23 VanDerWaalsContact C-N 3.31Å; Q21-I23 PolarHBondContact O-N 3.5Å; I23-V25 PolarHBondContact O-N 3.03Å; I23-K26 PolarHBondContact O-N 3.25Å; I23-Q27 WeakPolarHBondContact O-CG 3.41Å; I23-Q27 PolarHBondContact O-N 3.44Å; I23-Q27 VanDerWaalsContact O-N 3.14Å
24	N	69.6	Low	66.2	Low	96 Å²	96	98.5 Å²	98.5	51%	0.513	49%	0.491	S	S	.	.	H	α-helix	trans	-63.8	-40.4	179.5	-78.6	-20.8	0	0	0	112.8	Q21 Q27 I28	Q21-N24 PolarHBondContact O-N 3.49Å; N24-Q27 PolarHBondContact O-N 3.2Å; N24-I28 VanDerWaalsContact O-CG1 3.31Å; N24-I28 WeakPolarHBondContact O-CG1 3.32Å; N24-I28 PolarHBondContact O-N 3.42Å
25	V	72	Confident	68.8	Low	42 Å²	42	92.4 Å²	92.4	26%	0.255	48%	0.477	S	S	.	.	H	α-helix	trans	-64.8	-46	179.1	177.1	0	0	0	0	111.1	Q21 I23 Q27 I28 A29 Q277	Q21-V25 WeakPolarHBondContact O-CG2 3.48Å; Q21-V25 PolarHBondContact O-N 2.9Å; I23-V25 PolarHBondContact O-N 3.03Å; V25-Q27 VanDerWaalsContact C-N 3.3Å; V25-Q27 PolarHBondContact O-N 2.93Å; V25-I28 PolarHBondContact O-N 3.26Å; V25-A29 WeakPolarHBondContact O-CB 3.35Å; V25-A29 PolarHBondContact O-N 3.45Å; V25-Q277 HydrophobicContact CB-CG 4.38Å; V25-Q277 HydrophobicContact CG1-CG 3.85Å; V25-Q277 HydrophobicContact CG2-CG 3.63Å; V25-Q277 VanDerWaalsContact CG2-NE2 3.26Å
26	K	73.6	Confident	71.5	Confident	121 Å²	121	83.7 Å²	83.7	53%	0.526	45%	0.447	S	S	.	.	H	α-helix	trans	-61.2	-39.9	179.1	-169.5	177.5	179.4	-177.5	0	111.3	K22 I23 A29 A30	K22-K26 PolarHBondContact O-N 2.95Å; I23-K26 PolarHBondContact O-N 3.25Å; K26-A29 PolarHBondContact O-N 3.31Å; K26-A30 VanDerWaalsContact O-CB 3.28Å; K26-A30 WeakPolarHBondContact O-CB 3.47Å; K26-A30 PolarHBondContact O-N 3.04Å
27	Q	80.2	Confident	74.1	Confident	104 Å²	104	78 Å²	78	49%	0.486	41%	0.411	S	S	.	.	H	α-helix	trans	-67.2	-40.2	177	-72.9	178.3	-2.3	0	0	113.2	I23 N24 V25 A30 R31	I23-Q27 WeakPolarHBondContact O-CG 3.41Å; I23-Q27 PolarHBondContact O-N 3.44Å; I23-Q27 VanDerWaalsContact O-N 3.14Å; N24-Q27 PolarHBondContact O-N 3.2Å; V25-Q27 VanDerWaalsContact C-N 3.3Å; V25-Q27 PolarHBondContact O-N 2.93Å; Q27-A30 PolarHBondContact O-N 3.12Å; Q27-R31 WeakPolarHBondContact O-CG 3.42Å; Q27-R31 PolarHBondContact O-N 3.01Å
28	I	82.8	Confident	76.4	Confident	114 Å²	114	76.3 Å²	76.3	59%	0.585	40%	0.399	S	S	*	.	H	α-helix	trans	-65.2	-46.4	175.5	-67.5	165.5	0	0	0	110	N24 V25 A30 R31 L32	N24-I28 VanDerWaalsContact O-CG1 3.31Å; N24-I28 WeakPolarHBondContact O-CG1 3.32Å; N24-I28 PolarHBondContact O-N 3.42Å; V25-I28 PolarHBondContact O-N 3.26Å; I28-A30 VanDerWaalsContact C-N 3.33Å; I28-A30 PolarHBondContact O-N 3.08Å; I28-R31 PolarHBondContact O-N 3.46Å; I28-R31 VanDerWaalsContact O-N 3.16Å; I28-L32 WeakPolarHBondContact O-CB 3.47Å; I28-L32 PolarHBondContact O-N 3.47Å
29	A	83	Confident	78.6	Confident	19 Å²	19	76.4 Å²	76.4	16%	0.157	40%	0.402	C	S	.	.	H	α-helix	trans	-59	-43.3	176.6	0	0	0	0	0	111.7	V25 K26 R31 L32 L33	V25-A29 WeakPolarHBondContact O-CB 3.35Å; V25-A29 PolarHBondContact O-N 3.45Å; K26-A29 PolarHBondContact O-N 3.31Å; A29-R31 PolarHBondContact O-N 3.44Å; A29-L32 PolarHBondContact O-N 3.11Å; A29-L33 HydrophobicContact CB-CD1 3.82Å; A29-L33 HydrophobicContact CB-CG 4.27Å; A29-L33 VanDerWaalsContact O-CB 3.26Å; A29-L33 WeakPolarHBondContact O-CB 3.4Å; A29-L33 VanDerWaalsContact O-CG 3.24Å; A29-L33 WeakPolarHBondContact O-CG 3.28Å; A29-L33 PolarHBondContact O-N 2.8Å
30	A	84.9	Confident	80.7	Confident	29 Å²	29	72.8 Å²	72.8	24%	0.24	38%	0.379	C	S	.	.	H	α-helix	trans	-62.8	-25.5	177.8	0	0	0	0	0	114	K26 Q27 I28 P34 A90	K26-A30 VanDerWaalsContact O-CB 3.28Å; K26-A30 WeakPolarHBondContact O-CB 3.47Å; K26-A30 PolarHBondContact O-N 3.04Å; Q27-A30 PolarHBondContact O-N 3.12Å; I28-A30 VanDerWaalsContact C-N 3.33Å; I28-A30 PolarHBondContact O-N 3.08Å; A30-P34 VanDerWaalsContact O-CD 3.25Å; A30-P34 WeakPolarHBondContact O-CD 3.39Å; A30-P34 VanDerWaalsContact O-CG 3.25Å; A30-P34 WeakPolarHBondContact O-CG 3.2Å; A30-A90 VanDerWaalsContact CA-O 3.23Å; A30-A90 WeakPolarHBondContact CA-O 3.32Å; A30-A90 WeakPolarHBondContact CB-O 3.18Å
31	R	89.1	Confident	83	Confident	205 Å²	205	71.7 Å²	71.7	77%	0.774	36%	0.364	S	S	*	.	H	α-helix	trans	-88.2	-34.9	175.9	-68.5	-179.9	-177.1	-173	2.1	112.9	Q27 I28 A29 P35	Q27-R31 WeakPolarHBondContact O-CG 3.42Å; Q27-R31 PolarHBondContact O-N 3.01Å; I28-R31 PolarHBondContact O-N 3.46Å; I28-R31 VanDerWaalsContact O-N 3.16Å; A29-R31 PolarHBondContact O-N 3.44Å; R31-P35 WeakPolarHBondContact O-CD 3.35Å; R31-P35 WeakPolarHBondContact O-CG 3.49Å
32	L	90.3	Very high	85	Confident	108 Å²	108	72.4 Å²	72.4	57%	0.565	37%	0.369	S	S	*	.	H	α-helix	trans	-92.7	-38.4	-171.6	-168.4	120.7	0	0	0	113.5	I28 A29 P35 L36	I28-L32 WeakPolarHBondContact O-CB 3.47Å; I28-L32 PolarHBondContact O-N 3.47Å; A29-L32 PolarHBondContact O-N 3.11Å; L32-P35 WeakPolarHBondContact O-CD 3.35Å; L32-P35 WeakPolarHBondContact O-CG 3.46Å; L32-L36 WeakPolarHBondContact O-CB 3.41Å; L32-L36 PolarHBondContact O-N 3.17Å
33	L	90.6	Very high	86.6	Confident	8 Å²	8	73.5 Å²	73.5	4%	0.042	37%	0.374	C	S	.	.	H	α-helix	trans	-68.3	-44.8	-175	-62.4	176.6	0	0	0	113.4	A29 L36 Y37 A90 T284	A29-L33 HydrophobicContact CB-CD1 3.82Å; A29-L33 HydrophobicContact CB-CG 4.27Å; A29-L33 VanDerWaalsContact O-CB 3.26Å; A29-L33 WeakPolarHBondContact O-CB 3.4Å; A29-L33 VanDerWaalsContact O-CG 3.24Å; A29-L33 WeakPolarHBondContact O-CG 3.28Å; A29-L33 PolarHBondContact O-N 2.8Å; L33-L36 PolarHBondContact O-N 3.36Å; L33-Y37 HydrophobicContact CB-CD2 4.5Å; L33-Y37 HydrophobicContact CB-CE2 4.34Å; L33-Y37 HydrophobicContact CD2-CE1 4.37Å; L33-Y37 VanDerWaalsContact O-CB 3.3Å; L33-Y37 WeakPolarHBondContact O-CB 3.37Å; L33-Y37 PolarHBondContact O-N 3.39Å; L33-A90 HydrophobicContact CB-CB 3.89Å; L33-A90 HydrophobicContact CD1-CB 3.89Å; L33-T284 HydrophobicContact CD2-CG2 3.48Å; L33-T284 VanDerWaalsContact CD2-CG2 3.48Å; L33-T284 WeakPolarHBondContact CD2-OG1 3.19Å
34	P	92.4	Very high	88.1	Confident	25 Å²	25	69.2 Å²	69.2	16%	0.162	35%	0.352	C	S	.	.	H	α-helix	trans	-59.5	-48.4	-177.4	-22.3	33.1	0	0	0	115	A30 L36 S38 A91	A30-P34 VanDerWaalsContact O-CD 3.25Å; A30-P34 WeakPolarHBondContact O-CD 3.39Å; A30-P34 VanDerWaalsContact O-CG 3.25Å; A30-P34 WeakPolarHBondContact O-CG 3.2Å; P34-L36 PolarHBondContact O-N 3.01Å; P34-S38 WeakPolarHBondContact O-CB 3.21Å; P34-S38 PolarHBondContact O-N 2.88Å; P34-S38 PolarHBondContact O-OG 2.98Å; P34-A91 HydrophobicContact CB-CB 4.44Å; P34-A91 HydrophobicContact CG-CB 3.69Å
35	P	93.9	Very high	89.4	Confident	82 Å²	82	68.2 Å²	68.2	53%	0.532	34%	0.343	S	S	.	.	H	α-helix	trans	-66.7	-37	177	25.4	-32.7	0	0	0	112	R31 L32 S38 L39	R31-P35 WeakPolarHBondContact O-CD 3.35Å; R31-P35 WeakPolarHBondContact O-CG 3.49Å; L32-P35 WeakPolarHBondContact O-CD 3.35Å; L32-P35 WeakPolarHBondContact O-CG 3.46Å; P35-S38 PolarHBondContact O-N 3.02Å; P35-L39 WeakPolarHBondContact O-CB 3.37Å; P35-L39 PolarHBondContact O-N 3.22Å
36	L	93.7	Very high	90.4	Very high	56 Å²	56	70.5 Å²	70.5	29%	0.293	36%	0.357	S	S	.	.	H	α-helix	trans	-63.4	-49	176.8	179.2	63.3	0	0	0	111.7	L32 L33 P34 S38 L39 V40 T284	L32-L36 WeakPolarHBondContact O-CB 3.41Å; L32-L36 PolarHBondContact O-N 3.17Å; L33-L36 PolarHBondContact O-N 3.36Å; P34-L36 PolarHBondContact O-N 3.01Å; L36-S38 VanDerWaalsContact C-N 3.31Å; L36-S38 PolarHBondContact O-N 3.29Å; L36-L39 WeakPolarHBondContact O-CB 3.3Å; L36-L39 PolarHBondContact O-N 3.01Å; L36-L39 VanDerWaalsContact O-N 3.17Å; L36-V40 WeakPolarHBondContact O-CG2 3.36Å; L36-V40 PolarHBondContact O-N 3.25Å; L36-T284 HydrophobicContact CD2-CG2 3.52Å
37	Y	93.8	Very high	91.3	Very high	5 Å²	5	65.4 Å²	65.4	2%	0.02	34%	0.339	C	S	.	.	H	α-helix	trans	-65.1	-35.2	177.9	-75.4	-2.6	0	0	0	112.3	L33 L39 V40 F41 V83 W86 A87 T284 M287	L33-Y37 HydrophobicContact CB-CD2 4.5Å; L33-Y37 HydrophobicContact CB-CE2 4.34Å; L33-Y37 HydrophobicContact CD2-CE1 4.37Å; L33-Y37 VanDerWaalsContact O-CB 3.3Å; L33-Y37 WeakPolarHBondContact O-CB 3.37Å; L33-Y37 PolarHBondContact O-N 3.39Å; Y37-L39 VanDerWaalsContact C-N 3.34Å; Y37-L39 PolarHBondContact O-N 3.48Å; Y37-V40 PolarHBondContact O-N 3.33Å; Y37-F41 WeakPolarHBondContact O-CB 3.35Å; Y37-F41 PolarHBondContact O-N 3.25Å; Y37-V83 HydrophobicContact CG-CG1 4.02Å; Y37-V83 WeakPolarHBondContact O-CG1 3.35Å; Y37-W86 HydrophobicContact CD2-CB 4.27Å; Y37-W86 HydrophobicContact CE2-CB 4.08Å; Y37-A87 HydrophobicContact CD2-CB 4.11Å; Y37-A87 HydrophobicContact CG-CB 4.48Å; Y37-T284 HydrophobicContact CE1-CG2 3.88Å; Y37-M287 HydrophobicContact CE1-CB 4.05Å; Y37-M287 HydrophobicContact CE1-CG 4.4Å; Y37-M287 HydrophobicContact CE1-SD 4.28Å; Y37-M287 HydrophobicContact CE2-SD 4.23Å
38	S	94	Very high	92	Very high	60 Å²	60	60.5 Å²	60.5	42%	0.42	32%	0.316	S	S	.	.	H	α-helix	trans	-61.9	-42.8	171.9	-59.2	0	0	0	0	111.5	P34 P35 L36 F41 I42	P34-S38 WeakPolarHBondContact O-CB 3.21Å; P34-S38 PolarHBondContact O-N 2.88Å; P34-S38 PolarHBondContact O-OG 2.98Å; P35-S38 PolarHBondContact O-N 3.02Å; L36-S38 VanDerWaalsContact C-N 3.31Å; L36-S38 PolarHBondContact O-N 3.29Å; S38-F41 PolarHBondContact O-N 2.8Å; S38-I42 VanDerWaalsContact O-CG1 3.3Å; S38-I42 WeakPolarHBondContact O-CG1 3.4Å; S38-I42 PolarHBondContact O-N 3.39Å
39	L	94.3	Very high	92.5	Very high	89 Å²	89	58.2 Å²	58.2	47%	0.466	30%	0.304	S	S	.	.	H	α-helix	trans	-64.7	-44.7	176.5	-166.6	70.1	0	0	0	111.9	P35 L36 Y37 F41 I42 F43	P35-L39 WeakPolarHBondContact O-CB 3.37Å; P35-L39 PolarHBondContact O-N 3.22Å; L36-L39 WeakPolarHBondContact O-CB 3.3Å; L36-L39 PolarHBondContact O-N 3.01Å; L36-L39 VanDerWaalsContact O-N 3.17Å; Y37-L39 VanDerWaalsContact C-N 3.34Å; Y37-L39 PolarHBondContact O-N 3.48Å; L39-F41 VanDerWaalsContact C-N 3.31Å; L39-F41 PolarHBondContact O-N 3.43Å; L39-I42 PolarHBondContact O-N 2.89Å; L39-F43 HydrophobicContact CD1-CD2 3.88Å; L39-F43 HydrophobicContact CD1-CE2 3.29Å; L39-F43 HydrophobicContact CD1-CZ 4.04Å; L39-F43 HydrophobicContact CD2-CD2 4.46Å; L39-F43 HydrophobicContact CD2-CE2 4.04Å; L39-F43 HydrophobicContact CG-CD2 3.69Å; L39-F43 HydrophobicContact CG-CE2 3.49Å; L39-F43 VanDerWaalsContact CG-CE2 3.49Å; L39-F43 WeakPolarHBondContact O-CD2 3.38Å; L39-F43 PolarHBondContact O-N 3.22Å
40	V	94.8	Very high	92.9	Very high	8 Å²	8	59 Å²	59	5%	0.048	31%	0.305	C	S	.	.	H	α-helix	trans	-59.3	-43.8	174.9	171.1	0	0	0	0	110.7	L36 Y37 G44 L80 T288 C290 C291	L36-V40 WeakPolarHBondContact O-CG2 3.36Å; L36-V40 PolarHBondContact O-N 3.25Å; Y37-V40 PolarHBondContact O-N 3.33Å; V40-G44 WeakPolarHBondContact O-CA 3.46Å; V40-G44 PolarHBondContact O-N 2.98Å; V40-L80 HydrophobicContact CG1-CD2 4.29Å; V40-T288 HydrophobicContact CG2-CG2 3.77Å; V40-C290 VanDerWaalsContact CG1-SG 3.59Å; V40-C291 HydrophobicContact CG1-CB 4.49Å
41	F	95.4	Very high	93.2	Very high	59 Å²	59	57.8 Å²	57.8	26%	0.259	30%	0.295	S	S	.	.	H	α-helix	trans	-61.1	-49.8	177.1	179.5	-103.2	0	0	0	111.7	Y37 S38 L39 F45 L80 V83 P84	Y37-F41 WeakPolarHBondContact O-CB 3.35Å; Y37-F41 PolarHBondContact O-N 3.25Å; S38-F41 PolarHBondContact O-N 2.8Å; L39-F41 VanDerWaalsContact C-N 3.31Å; L39-F41 PolarHBondContact O-N 3.43Å; F41-F45 HydrophobicContact CE2-CD2 4.38Å; F41-F45 HydrophobicContact CZ-CD2 4.31Å; F41-F45 WeakPolarHBondContact O-CB 3.4Å; F41-F45 PolarHBondContact O-N 3.46Å; F41-L80 HydrophobicContact CD2-CB 4.47Å; F41-L80 VanDerWaalsContact CD2-O 3.3Å; F41-L80 WeakPolarHBondContact CD2-O 3.33Å; F41-V83 HydrophobicContact CB-CG1 4.39Å; F41-P84 HydrophobicContact CD1-CG 4.36Å; F41-P84 HydrophobicContact CD2-CG 3.67Å; F41-P84 HydrophobicContact CE1-CG 4.48Å; F41-P84 HydrophobicContact CE2-CG 3.81Å; F41-P84 HydrophobicContact CG-CG 3.95Å; F41-P84 HydrophobicContact CZ-CG 4.22Å
42	I	94.6	Very high	93.3	Very high	99 Å²	99	49.1 Å²	49.1	51%	0.508	26%	0.264	S	S	.	.	H	α-helix	trans	-60.9	-54.5	-178.6	-67.8	164.9	0	0	0	110.9	S38 L39 V46	S38-I42 VanDerWaalsContact O-CG1 3.3Å; S38-I42 WeakPolarHBondContact O-CG1 3.4Å; S38-I42 PolarHBondContact O-N 3.39Å; L39-I42 PolarHBondContact O-N 2.89Å; I42-V46 WeakPolarHBondContact O-CB 3.42Å; I42-V46 VanDerWaalsContact O-CG2 3.3Å; I42-V46 WeakPolarHBondContact O-CG2 3.4Å; I42-V46 PolarHBondContact O-N 2.94Å; I42-V46 VanDerWaalsContact O-N 3.09Å
43	F	93.4	Very high	93.3	Very high	125 Å²	125	47.6 Å²	47.6	55%	0.548	26%	0.255	S	S	.	.	H	α-helix	trans	-68.1	-40.4	-178	-71.4	-52.1	0	0	0	112.4	L39 G47 C291	L39-F43 HydrophobicContact CD1-CD2 3.88Å; L39-F43 HydrophobicContact CD1-CE2 3.29Å; L39-F43 HydrophobicContact CD1-CZ 4.04Å; L39-F43 HydrophobicContact CD2-CD2 4.46Å; L39-F43 HydrophobicContact CD2-CE2 4.04Å; L39-F43 HydrophobicContact CG-CD2 3.69Å; L39-F43 HydrophobicContact CG-CE2 3.49Å; L39-F43 VanDerWaalsContact CG-CE2 3.49Å; L39-F43 WeakPolarHBondContact O-CD2 3.38Å; L39-F43 PolarHBondContact O-N 3.22Å; F43-G47 WeakPolarHBondContact O-CA 3.36Å; F43-G47 PolarHBondContact O-N 3.05Å; F43-C291 HydrophobicContact CB-CB 4.41Å
44	G	94.4	Very high	93.2	Very high	0 Å²	0	47.2 Å²	47.2	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-64.7	-45.4	178.4	0	0	0	0	0	111.9	V40 N48 L80	V40-G44 WeakPolarHBondContact O-CA 3.46Å; V40-G44 PolarHBondContact O-N 2.98Å; G44-N48 VanDerWaalsContact O-CB 3.28Å; G44-N48 WeakPolarHBondContact O-CB 3.25Å; G44-N48 PolarHBondContact O-N 3.46Å; G44-N48 PolarHBondContact O-ND2 2.94Å; G44-L80 WeakPolarHBondContact O-CD1 3.34Å
45	F	95.3	Very high	93	Very high	74 Å²	74	46.1 Å²	46.1	33%	0.325	25%	0.246	S	C	.	.	H	α-helix	trans	-65.9	-51.3	-179.3	-172.3	-92.4	0	0	0	111.1	F41 G47 M49 L77	F41-F45 HydrophobicContact CE2-CD2 4.38Å; F41-F45 HydrophobicContact CZ-CD2 4.31Å; F41-F45 WeakPolarHBondContact O-CB 3.4Å; F41-F45 PolarHBondContact O-N 3.46Å; F45-G47 PolarHBondContact O-N 3.23Å; F45-M49 HydrophobicContact CD1-CG 4.17Å; F45-M49 HydrophobicContact CD2-CE 4.36Å; F45-M49 HydrophobicContact CE1-CE 4.33Å; F45-M49 HydrophobicContact CE1-CG 3.95Å; F45-M49 HydrophobicContact CE2-CE 3.58Å; F45-M49 HydrophobicContact CE2-CG 4.48Å; F45-M49 HydrophobicContact CZ-CE 3.56Å; F45-M49 HydrophobicContact CZ-CG 4.12Å; F45-M49 VanDerWaalsContact O-CB 3.24Å; F45-M49 WeakPolarHBondContact O-CB 3.35Å; F45-M49 WeakPolarHBondContact O-CG 3.43Å; F45-M49 PolarHBondContact O-N 3.37Å; F45-L77 HydrophobicContact CD2-CD2 3.96Å; F45-L77 HydrophobicContact CE2-CD2 4.37Å
46	V	93.7	Very high	92.7	Very high	90 Å²	90	46 Å²	46	55%	0.545	24%	0.241	S	C	.	.	H	α-helix	trans	-61.8	-45.1	178.8	175	0	0	0	0	110.9	I42 L50	I42-V46 WeakPolarHBondContact O-CB 3.42Å; I42-V46 VanDerWaalsContact O-CG2 3.3Å; I42-V46 WeakPolarHBondContact O-CG2 3.4Å; I42-V46 PolarHBondContact O-N 2.94Å; I42-V46 VanDerWaalsContact O-N 3.09Å; V46-L50 VanDerWaalsContact O-CB 3.29Å; V46-L50 WeakPolarHBondContact O-CB 3.34Å; V46-L50 PolarHBondContact O-N 3.09Å
47	G	92.4	Very high	92.3	Very high	14 Å²	14	47.7 Å²	47.7	14%	0.144	25%	0.25	C	C	.	.	H	α-helix	trans	-62.3	-51.8	-179.7	0	0	0	0	0	112.7	F43 F45 L50 V51 P294	F43-G47 WeakPolarHBondContact O-CA 3.36Å; F43-G47 PolarHBondContact O-N 3.05Å; F45-G47 PolarHBondContact O-N 3.23Å; G47-L50 WeakPolarHBondContact O-CB 3.24Å; G47-L50 PolarHBondContact O-N 2.77Å; G47-V51 WeakPolarHBondContact O-CG2 3.5Å; G47-V51 PolarHBondContact O-N 3Å; G47-P294 VanDerWaalsContact C-CG 3.41Å
48	N	94.6	Very high	91.6	Very high	1 Å²	1	49.5 Å²	49.5	1%	0.005	26%	0.262	C	S	.	.	H	α-helix	trans	-69.5	-36.6	-178.4	-74.2	-62.1	0	0	0	112.3	G44 L50 V51 I52 L77 C290 P294	G44-N48 VanDerWaalsContact O-CB 3.28Å; G44-N48 WeakPolarHBondContact O-CB 3.25Å; G44-N48 PolarHBondContact O-N 3.46Å; G44-N48 PolarHBondContact O-ND2 2.94Å; N48-L50 VanDerWaalsContact C-N 3.32Å; N48-L50 PolarHBondContact O-N 3.08Å; N48-V51 WeakPolarHBondContact O-CB 3.44Å; N48-V51 PolarHBondContact O-N 3.28Å; N48-I52 WeakPolarHBondContact O-CG1 3.39Å; N48-I52 PolarHBondContact O-N 3.23Å; N48-L77 HydrophobicContact CB-CD2 3.97Å; N48-L77 HydrophobicContact CB-CG 4.11Å; N48-C290 PolarHBondContact ND2-O 2.88Å; N48-P294 WeakPolarHBondContact OD1-CG 3.42Å
49	M	93.8	Very high	90.9	Very high	67 Å²	67	48.5 Å²	48.5	33%	0.33	25%	0.251	S	S	.	.	H	α-helix	trans	-61.6	-41.1	172.1	-74.3	-62.3	176.8	0	0	112	F45 V51 I52 L53 L77	F45-M49 HydrophobicContact CD1-CG 4.17Å; F45-M49 HydrophobicContact CD2-CE 4.36Å; F45-M49 HydrophobicContact CE1-CE 4.33Å; F45-M49 HydrophobicContact CE1-CG 3.95Å; F45-M49 HydrophobicContact CE2-CE 3.58Å; F45-M49 HydrophobicContact CE2-CG 4.48Å; F45-M49 HydrophobicContact CZ-CE 3.56Å; F45-M49 HydrophobicContact CZ-CG 4.12Å; F45-M49 VanDerWaalsContact O-CB 3.24Å; F45-M49 WeakPolarHBondContact O-CB 3.35Å; F45-M49 WeakPolarHBondContact O-CG 3.43Å; F45-M49 PolarHBondContact O-N 3.37Å; M49-V51 VanDerWaalsContact C-N 3.34Å; M49-V51 PolarHBondContact O-N 3.15Å; M49-I52 PolarHBondContact O-N 2.95Å; M49-I52 HydrophobicContact SD-CD1 4.45Å; M49-L53 WeakPolarHBondContact O-CB 3.21Å; M49-L53 VanDerWaalsContact O-CG 3.3Å; M49-L53 WeakPolarHBondContact O-CG 3.25Å; M49-L53 PolarHBondContact O-N 3.02Å; M49-L77 HydrophobicContact CE-CD1 3.45Å; M49-L77 VanDerWaalsContact CE-CD1 3.45Å; M49-L77 HydrophobicContact CE-CD2 3.91Å; M49-L77 HydrophobicContact CE-CG 4.34Å; M49-L77 HydrophobicContact CG-CD2 4.42Å; M49-L77 HydrophobicContact SD-CD1 3.91Å
50	L	90.8	Very high	90.5	Very high	36 Å²	36	53.1 Å²	53.1	19%	0.188	26%	0.262	C	S	.	.	H	α-helix	trans	-64.3	-39.6	176.3	-173.4	57.4	0	0	0	112	V46 G47 N48 L53 I54 L308 F311	V46-L50 VanDerWaalsContact O-CB 3.29Å; V46-L50 WeakPolarHBondContact O-CB 3.34Å; V46-L50 PolarHBondContact O-N 3.09Å; G47-L50 WeakPolarHBondContact O-CB 3.24Å; G47-L50 PolarHBondContact O-N 2.77Å; N48-L50 VanDerWaalsContact C-N 3.32Å; N48-L50 PolarHBondContact O-N 3.08Å; L50-L53 PolarHBondContact O-N 2.94Å; L50-I54 HydrophobicContact CD1-CD1 4.14Å; L50-I54 HydrophobicContact CD1-CG1 4.46Å; L50-I54 HydrophobicContact CG-CD1 4.01Å; L50-I54 WeakPolarHBondContact O-CB 3.44Å; L50-I54 VanDerWaalsContact O-CG1 3.3Å; L50-I54 WeakPolarHBondContact O-CG1 3.46Å; L50-I54 PolarHBondContact O-N 3.32Å; L50-L308 HydrophobicContact CD1-CD2 4.24Å; L50-L308 HydrophobicContact CD2-CD2 3.3Å; L50-L308 HydrophobicContact CG-CD2 3.74Å; L50-F311 HydrophobicContact CD1-CD1 3.82Å; L50-F311 HydrophobicContact CD1-CE1 3.67Å; L50-F311 HydrophobicContact CD1-CZ 4.37Å
51	V	91.1	Very high	90	Very high	2 Å²	2	55.1 Å²	55.1	1%	0.012	27%	0.272	C	S	.	.	H	α-helix	trans	-58.3	-50.7	172.7	172.7	0	0	0	0	110.6	G47 N48 M49 L53 I54 L55 A73 P294 Y297 F304	G47-V51 WeakPolarHBondContact O-CG2 3.5Å; G47-V51 PolarHBondContact O-N 3Å; N48-V51 WeakPolarHBondContact O-CB 3.44Å; N48-V51 PolarHBondContact O-N 3.28Å; M49-V51 VanDerWaalsContact C-N 3.34Å; M49-V51 PolarHBondContact O-N 3.15Å; V51-L53 PolarHBondContact O-N 2.66Å; V51-I54 PolarHBondContact O-N 2.74Å; V51-L55 HydrophobicContact CG1-CD1 3.79Å; V51-L55 HydrophobicContact CG1-CG 4.25Å; V51-L55 WeakPolarHBondContact O-CB 3.46Å; V51-L55 VanDerWaalsContact O-CG 3.26Å; V51-L55 WeakPolarHBondContact O-CG 3.36Å; V51-L55 PolarHBondContact O-N 3.23Å; V51-A73 HydrophobicContact CB-CB 4.47Å; V51-A73 HydrophobicContact CG1-CB 4.07Å; V51-P294 HydrophobicContact CG2-CB 4.09Å; V51-P294 HydrophobicContact CG2-CG 4.19Å; V51-Y297 HydrophobicContact CG1-CD2 4.28Å; V51-Y297 HydrophobicContact CG1-CE2 4.18Å; V51-Y297 HydrophobicContact CG2-CD2 3.73Å; V51-Y297 HydrophobicContact CG2-CE2 4.2Å; V51-F304 HydrophobicContact CB-CE2 4.44Å; V51-F304 HydrophobicContact CB-CZ 4.33Å; V51-F304 HydrophobicContact CG2-CE1 4.43Å; V51-F304 HydrophobicContact CG2-CE2 4.06Å; V51-F304 HydrophobicContact CG2-CZ 3.58Å
52	I	93.1	Very high	89.5	Confident	24 Å²	24	59.9 Å²	59.9	12%	0.123	29%	0.293	C	S	.	.	H	α-helix	trans	-57.6	-48.8	178.8	-68.5	168.9	0	0	0	110.8	N48 M49 I54 L55 I56 L70 A73 I74 L77	N48-I52 WeakPolarHBondContact O-CG1 3.39Å; N48-I52 PolarHBondContact O-N 3.23Å; M49-I52 PolarHBondContact O-N 2.95Å; M49-I52 HydrophobicContact SD-CD1 4.45Å; I52-I54 VanDerWaalsContact C-N 3.34Å; I52-I54 PolarHBondContact O-N 3.45Å; I52-L55 PolarHBondContact O-N 3.12Å; I52-I56 HydrophobicContact CG2-CD1 3.68Å; I52-I56 HydrophobicContact CG2-CG1 4.47Å; I52-I56 WeakPolarHBondContact O-CG1 3.42Å; I52-I56 PolarHBondContact O-N 3Å; I52-L70 HydrophobicContact CB-CD1 4.25Å; I52-L70 HydrophobicContact CG1-CD1 3.98Å; I52-L70 HydrophobicContact CG2-CD1 3.93Å; I52-A73 HydrophobicContact CD1-CB 4.23Å; I52-A73 HydrophobicContact CG1-CB 3.8Å; I52-I74 HydrophobicContact CD1-CG1 4.25Å; I52-L77 HydrophobicContact CD1-CD1 3.36Å; I52-L77 HydrophobicContact CD1-CG 4.41Å
53	L	89.9	Confident	89.1	Confident	75 Å²	75	57 Å²	57	39%	0.393	28%	0.281	S	S	.	.	H	α-helix	trans	-59.4	-42.8	179.2	-73.5	170.7	0	0	0	112.3	M49 L50 V51 N57 F311	M49-L53 WeakPolarHBondContact O-CB 3.21Å; M49-L53 VanDerWaalsContact O-CG 3.3Å; M49-L53 WeakPolarHBondContact O-CG 3.25Å; M49-L53 PolarHBondContact O-N 3.02Å; L50-L53 PolarHBondContact O-N 2.94Å; V51-L53 PolarHBondContact O-N 2.66Å; L53-N57 WeakPolarHBondContact O-CB 3.35Å; L53-N57 PolarHBondContact O-N 2.61Å; L53-N57 PolarHBondContact O-ND2 3.2Å; L53-F311 HydrophobicContact CD1-CZ 4.35Å
54	I	86.9	Confident	88.9	Confident	0 Å²	0	51.3 Å²	51.3	0%	0	26%	0.257	C	S	.	.	I	π-helix	trans	-67.1	-41.9	178	-72.4	167.2	0	0	0	111.1	L50 V51 I52 C58 K59 F304 Y307 L308	L50-I54 HydrophobicContact CD1-CD1 4.14Å; L50-I54 HydrophobicContact CD1-CG1 4.46Å; L50-I54 HydrophobicContact CG-CD1 4.01Å; L50-I54 WeakPolarHBondContact O-CB 3.44Å; L50-I54 VanDerWaalsContact O-CG1 3.3Å; L50-I54 WeakPolarHBondContact O-CG1 3.46Å; L50-I54 PolarHBondContact O-N 3.32Å; V51-I54 PolarHBondContact O-N 2.74Å; I52-I54 VanDerWaalsContact C-N 3.34Å; I52-I54 PolarHBondContact O-N 3.45Å; I54-C58 HydrophobicContact CG2-CB 4.29Å; I54-C58 WeakPolarHBondContact O-CA 3.42Å; I54-C58 VanDerWaalsContact O-CB 3.25Å; I54-C58 WeakPolarHBondContact O-CB 3.36Å; I54-C58 PolarHBondContact O-N 3.43Å; I54-K59 PolarHBondContact O-N 2.63Å; I54-F304 HydrophobicContact CB-CE2 4.03Å; I54-F304 HydrophobicContact CD1-CD2 4.41Å; I54-F304 HydrophobicContact CD1-CE1 4.36Å; I54-F304 HydrophobicContact CD1-CE2 3.65Å; I54-F304 HydrophobicContact CD1-CZ 3.61Å; I54-F304 HydrophobicContact CG1-CE2 4.45Å; I54-F304 HydrophobicContact CG2-CD2 4.05Å; I54-F304 HydrophobicContact CG2-CE2 3.85Å; I54-Y307 HydrophobicContact CG2-CG 4.28Å; I54-L308 HydrophobicContact CD1-CD2 3.52Å; I54-L308 HydrophobicContact CD1-CG 3.68Å
55	L	88.3	Confident	88.6	Confident	3 Å²	3	51.9 Å²	51.9	2%	0.016	26%	0.261	C	S	.	.	I	π-helix	trans	-64.4	-42.2	-179.8	-70.9	177.3	0	0	0	111.9	V51 I52 K59 R60 L61 D66 L69 L70	V51-L55 HydrophobicContact CG1-CD1 3.79Å; V51-L55 HydrophobicContact CG1-CG 4.25Å; V51-L55 WeakPolarHBondContact O-CB 3.46Å; V51-L55 VanDerWaalsContact O-CG 3.26Å; V51-L55 WeakPolarHBondContact O-CG 3.36Å; V51-L55 PolarHBondContact O-N 3.23Å; I52-L55 PolarHBondContact O-N 3.12Å; L55-K59 HydrophobicContact CD2-CD 3.96Å; L55-K59 CarbonylContact O-C 3.58Å; L55-R60 PolarHBondContact O-N 2.83Å; L55-L61 HydrophobicContact CB-CD2 3.92Å; L55-L61 PolarHBondContact O-N 3.14Å; L55-D66 HydrophobicContact CD2-CB 4.32Å; L55-L69 HydrophobicContact CD1-CB 3.91Å; L55-L70 HydrophobicContact CD1-CB 4Å
56	I	89	Confident	88.4	Confident	80 Å²	80	49.1 Å²	49.1	41%	0.41	25%	0.249	S	C	.	.	I	π-helix	trans	-75.5	-54.2	179.7	-64	173.7	0	0	0	110.9	I52 R60 L61 L70	I52-I56 HydrophobicContact CG2-CD1 3.68Å; I52-I56 HydrophobicContact CG2-CG1 4.47Å; I52-I56 WeakPolarHBondContact O-CG1 3.42Å; I52-I56 PolarHBondContact O-N 3Å; I56-R60 WeakPolarHBondContact O-CA 3.17Å; I56-R60 PolarHBondContact O-N 2.85Å; I56-L61 HydrophobicContact CG1-CD1 4.38Å; I56-L70 HydrophobicContact CD1-CD1 4.41Å; I56-L70 HydrophobicContact CG1-CD1 4.39Å
57	N	83.8	Confident	88.4	Confident	91 Å²	91	45.4 Å²	45.4	49%	0.487	23%	0.226	S	C	.	.	I	π-helix	trans	-84.5	-37.3	-168.3	-62.5	-34.9	0	0	0	113.5	L53	L53-N57 WeakPolarHBondContact O-CB 3.35Å; L53-N57 PolarHBondContact O-N 2.61Å; L53-N57 PolarHBondContact O-ND2 3.2Å
58	C	80.4	Confident	88.5	Confident	42 Å²	42	45.5 Å²	45.5	28%	0.284	22%	0.222	S	C	.	.	I	π-helix	trans	-95.1	-47.6	-175.6	-55.6	0	0	0	0	111.9	I54 Y307	I54-C58 HydrophobicContact CG2-CB 4.29Å; I54-C58 WeakPolarHBondContact O-CA 3.42Å; I54-C58 VanDerWaalsContact O-CB 3.25Å; I54-C58 WeakPolarHBondContact O-CB 3.36Å; I54-C58 PolarHBondContact O-N 3.43Å; C58-Y307 HydrophobicContact CB-CD1 3.71Å; C58-Y307 HydrophobicContact CB-CE1 4.26Å; C58-Y307 HydrophobicContact CB-CG 4.27Å
59	K	79.8	Confident	88.3	Confident	40 Å²	40	46.4 Å²	46.4	17%	0.174	23%	0.227	C	C	.	.	I	π-helix	trans	-87.9	-22.7	-178	-73.1	-159.3	-177.8	171.6	0	114.7	I54 L55 L61 D66 Y307	I54-K59 PolarHBondContact O-N 2.63Å; L55-K59 HydrophobicContact CD2-CD 3.96Å; L55-K59 CarbonylContact O-C 3.58Å; K59-L61 PolarHBondContact O-N 2.94Å; K59-D66 WeakPolarHBondContact CD-OD1 3.48Å; K59-D66 IonicContact NZ-OD1 3.7Å; K59-D66 PolarHBondContact NZ-OD1 3.15Å; K59-Y307 HydrophobicContact CD-CE2 4.28Å; K59-Y307 HydrophobicContact CG-CD2 4.16Å; K59-Y307 HydrophobicContact CG-CE2 3.79Å
60	R	84.4	Confident	88.4	Confident	185 Å²	185	44.4 Å²	44.4	70%	0.698	22%	0.217	S	C	*	.	T	Hydrogen-bonded Turn	trans	55.4	32	-180	-53.2	-175.3	-178.2	-177.1	-0.3	114	L55 I56 K62	L55-R60 PolarHBondContact O-N 2.83Å; I56-R60 WeakPolarHBondContact O-CA 3.17Å; I56-R60 PolarHBondContact O-N 2.85Å; R60-K62 HydrophobicContact CB-CG 4.36Å; R60-K62 PolarHBondContact O-N 3.38Å
61	L	85.4	Confident	88.7	Confident	50 Å²	50	43.6 Å²	43.6	26%	0.262	21%	0.213	S	C	.	.	T	Hydrogen-bonded Turn	trans	47	38.8	172.5	-54.5	174.7	0	0	0	115.2	L55 I56 K59 S63 D66 L70	L55-L61 HydrophobicContact CB-CD2 3.92Å; L55-L61 PolarHBondContact O-N 3.14Å; I56-L61 HydrophobicContact CG1-CD1 4.38Å; K59-L61 PolarHBondContact O-N 2.94Å; L61-S63 PolarHBondContact O-N 3.31Å; L61-D66 HydrophobicContact CD2-CB 4.24Å; L61-L70 HydrophobicContact CD1-CD2 3.79Å; L61-L70 HydrophobicContact CD2-CB 4.21Å; L61-L70 HydrophobicContact CD2-CD2 4.04Å
62	K	83.4	Confident	88.8	Confident	159 Å²	159	43.6 Å²	43.6	69%	0.691	21%	0.213	S	C	*	.			trans	-74.8	-6.9	-172.3	-65.2	-175.1	179.8	-172.6	0	114.7	R60	R60-K62 HydrophobicContact CB-CG 4.36Å; R60-K62 PolarHBondContact O-N 3.38Å
63	S	86.8	Confident	88.9	Confident	39 Å²	39	42.5 Å²	42.5	27%	0.273	21%	0.208	S	C	.	.	S	Bend	trans	-133.1	149.2	-177.2	74.2	0	0	0	0	111.6	L61 T65 D66 I67	L61-S63 PolarHBondContact O-N 3.31Å; S63-T65 PolarHBondContact O-N 3.03Å; S63-T65 VanDerWaalsContact O-N 3.12Å; S63-D66 PolarHBondContact O-N 3.1Å; S63-D66 PolarHBondContact OG-N 3.1Å; S63-D66 PolarHBondContact OG-OD2 2.9Å; S63-I67 PolarHBondContact O-N 2.79Å
64	T	89	Confident	89.3	Confident	6 Å²	6	41.3 Å²	41.3	4%	0.037	20%	0.201	C	C	.	.	H	α-helix	trans	-50.4	-36.2	174.3	-50.2	0	0	0	0	112.1	I67 Y68 R140 T141	T64-I67 WeakPolarHBondContact O-CB 3.32Å; T64-I67 PolarHBondContact O-N 3.11Å; T64-Y68 HydrophobicContact CG2-CD2 4.28Å; T64-Y68 HydrophobicContact CG2-CE1 4.18Å; T64-Y68 HydrophobicContact CG2-CE2 3.61Å; T64-Y68 PolarHBondContact O-N 3.26Å; T64-R140 VanDerWaalsContact OG1-C 3.26Å; T64-R140 PolarHBondContact OG1-O 3.39Å; T64-T141 PolarHBondContact OG1-O 3.42Å; T64-T141 VanDerWaalsContact OG1-O 3.11Å
65	T	89.3	Confident	89.8	Confident	12 Å²	12	41.3 Å²	41.3	7%	0.074	20%	0.201	C	C	.	.	H	α-helix	trans	-67	-38.8	177.4	-41	0	0	0	0	113	S63 I67 Y68 L69 L122 D125 R126 R140	S63-T65 PolarHBondContact O-N 3.03Å; S63-T65 VanDerWaalsContact O-N 3.12Å; T65-I67 PolarHBondContact O-N 3.3Å; T65-Y68 PolarHBondContact O-N 3.21Å; T65-L69 HydrophobicContact CG2-CD1 4.38Å; T65-L69 WeakPolarHBondContact O-CB 3.39Å; T65-L69 VanDerWaalsContact O-CG 3.28Å; T65-L69 WeakPolarHBondContact O-CG 3.48Å; T65-L69 PolarHBondContact O-N 3.35Å; T65-L122 HydrophobicContact CG2-CD2 3.65Å; T65-D125 PolarHBondContact OG1-OD2 3.05Å; T65-R126 PolarHBondContact OG1-NH2 3.49Å; T65-R140 PolarHBondContact OG1-NH2 2.84Å
66	D	90.1	Very high	90.1	Very high	16 Å²	16	41.6 Å²	41.6	9%	0.086	20%	0.203	C	C	.	.	H	α-helix	trans	-66.9	-31.3	176.4	-60.8	-49.2	0	0	0	110.4	L55 K59 L61 S63 L70	L55-D66 HydrophobicContact CD2-CB 4.32Å; K59-D66 WeakPolarHBondContact CD-OD1 3.48Å; K59-D66 IonicContact NZ-OD1 3.7Å; K59-D66 PolarHBondContact NZ-OD1 3.15Å; L61-D66 HydrophobicContact CD2-CB 4.24Å; S63-D66 PolarHBondContact O-N 3.1Å; S63-D66 PolarHBondContact OG-N 3.1Å; S63-D66 PolarHBondContact OG-OD2 2.9Å; D66-L70 WeakPolarHBondContact O-CB 3.42Å; D66-L70 PolarHBondContact O-N 3.2Å
67	I	93.6	Very high	90.5	Very high	12 Å²	12	38.6 Å²	38.6	6%	0.062	19%	0.188	C	C	.	.	H	α-helix	trans	-66.1	-47.3	172.3	-56.1	170.8	0	0	0	110.8	S63 T64 T65 L70 N71 V142 V146	S63-I67 PolarHBondContact O-N 2.79Å; T64-I67 WeakPolarHBondContact O-CB 3.32Å; T64-I67 PolarHBondContact O-N 3.11Å; T65-I67 PolarHBondContact O-N 3.3Å; I67-L70 WeakPolarHBondContact O-CB 3.25Å; I67-L70 PolarHBondContact O-N 2.98Å; I67-N71 PolarHBondContact O-N 2.85Å; I67-N71 PolarHBondContact O-ND2 2.98Å; I67-V142 HydrophobicContact CD1-CB 4.13Å; I67-V142 HydrophobicContact CD1-CG1 3.73Å; I67-V142 HydrophobicContact CD1-CG2 4.34Å; I67-V142 WeakPolarHBondContact CD1-O 3.41Å; I67-V146 HydrophobicContact CD1-CG2 4.13Å
68	Y	94.1	Very high	91	Very high	16 Å²	16	37.5 Å²	37.5	6%	0.063	18%	0.178	C	C	.	.	H	α-helix	trans	-66.8	-38	178.6	-61.9	-23.5	0	0	0	112.5	T64 T65 L70 N71 L72 F118 L121 L122 D125 T148	T64-Y68 HydrophobicContact CG2-CD2 4.28Å; T64-Y68 HydrophobicContact CG2-CE1 4.18Å; T64-Y68 HydrophobicContact CG2-CE2 3.61Å; T64-Y68 PolarHBondContact O-N 3.26Å; T65-Y68 PolarHBondContact O-N 3.21Å; Y68-L70 VanDerWaalsContact C-N 3.31Å; Y68-L70 PolarHBondContact O-N 2.99Å; Y68-N71 PolarHBondContact O-N 3.35Å; Y68-L72 WeakPolarHBondContact O-CB 3.49Å; Y68-L72 PolarHBondContact O-N 3.16Å; Y68-F118 HydrophobicContact CD1-CD1 4.21Å; Y68-F118 HydrophobicContact CD1-CE1 4.34Å; Y68-L121 HydrophobicContact CD1-CD1 4.4Å; Y68-L121 HydrophobicContact CD2-CB 3.96Å; Y68-L121 HydrophobicContact CE1-CD1 4.1Å; Y68-L121 HydrophobicContact CE2-CB 3.89Å; Y68-L121 HydrophobicContact CG-CB 4.32Å; Y68-L122 HydrophobicContact CD2-CD2 4.4Å; Y68-D125 HydrophobicContact CD2-CB 4.26Å; Y68-D125 HydrophobicContact CE2-CB 4.07Å; Y68-T148 WeakPolarHBondContact CE1-OG1 3.31Å; Y68-T148 PolarHBondContact OH-OG1 2.79Å
69	L	92.1	Very high	91.7	Very high	20 Å²	20	35.8 Å²	35.8	11%	0.105	17%	0.166	C	C	.	.	H	α-helix	trans	-63.6	-36.9	172.5	-71.8	171.9	0	0	0	112.1	L55 T65 A73 L122 Y297	L55-L69 HydrophobicContact CD1-CB 3.91Å; T65-L69 HydrophobicContact CG2-CD1 4.38Å; T65-L69 WeakPolarHBondContact O-CB 3.39Å; T65-L69 VanDerWaalsContact O-CG 3.28Å; T65-L69 WeakPolarHBondContact O-CG 3.48Å; T65-L69 PolarHBondContact O-N 3.35Å; L69-A73 PolarHBondContact O-N 3.24Å; L69-A73 VanDerWaalsContact O-N 3.08Å; L69-L122 HydrophobicContact CD2-CD1 3.87Å; L69-L122 HydrophobicContact CD2-CD2 4.22Å; L69-L122 HydrophobicContact CG-CD2 4.09Å; L69-Y297 HydrophobicContact CD2-CE1 4.05Å; L69-Y297 WeakPolarHBondContact CD2-OH 3.25Å
70	L	94.6	Very high	92.5	Very high	25 Å²	25	33.9 Å²	33.9	13%	0.131	16%	0.158	C	C	.	.	H	α-helix	trans	-63.7	-48.3	174.7	177.4	70.5	0	0	0	110.9	I52 L55 I56 L61 D66 I67 Y68 L72 A73 I74	I52-L70 HydrophobicContact CB-CD1 4.25Å; I52-L70 HydrophobicContact CG1-CD1 3.98Å; I52-L70 HydrophobicContact CG2-CD1 3.93Å; L55-L70 HydrophobicContact CD1-CB 4Å; I56-L70 HydrophobicContact CD1-CD1 4.41Å; I56-L70 HydrophobicContact CG1-CD1 4.39Å; L61-L70 HydrophobicContact CD1-CD2 3.79Å; L61-L70 HydrophobicContact CD2-CB 4.21Å; L61-L70 HydrophobicContact CD2-CD2 4.04Å; D66-L70 WeakPolarHBondContact O-CB 3.42Å; D66-L70 PolarHBondContact O-N 3.2Å; I67-L70 WeakPolarHBondContact O-CB 3.25Å; I67-L70 PolarHBondContact O-N 2.98Å; Y68-L70 VanDerWaalsContact C-N 3.31Å; Y68-L70 PolarHBondContact O-N 2.99Å; L70-L72 VanDerWaalsContact C-N 3.32Å; L70-L72 PolarHBondContact O-N 2.88Å; L70-A73 PolarHBondContact O-N 3.4Å; L70-I74 HydrophobicContact CD1-CD1 4.46Å; L70-I74 HydrophobicContact CG-CD1 4.07Å; L70-I74 WeakPolarHBondContact O-CG1 3.44Å; L70-I74 PolarHBondContact O-N 3.01Å
71	N	96.8	Very high	93	Very high	19 Å²	19	29 Å²	29	10%	0.102	15%	0.145	C	C	.	.	H	α-helix	trans	-66.2	-34.8	179.7	-75.3	-81.4	0	0	0	112.4	I67 Y68 I74 S75 F118 S149 W153	I67-N71 PolarHBondContact O-N 2.85Å; I67-N71 PolarHBondContact O-ND2 2.98Å; Y68-N71 PolarHBondContact O-N 3.35Å; N71-I74 PolarHBondContact O-N 2.97Å; N71-S75 WeakPolarHBondContact O-CB 3.38Å; N71-S75 PolarHBondContact O-N 3.12Å; N71-F118 HydrophobicContact CB-CD1 3.78Å; N71-F118 HydrophobicContact CB-CD2 3.77Å; N71-F118 HydrophobicContact CB-CE1 3.46Å; N71-F118 VanDerWaalsContact CB-CE1 3.46Å; N71-F118 HydrophobicContact CB-CE2 3.47Å; N71-F118 VanDerWaalsContact CB-CE2 3.47Å; N71-F118 HydrophobicContact CB-CG 3.96Å; N71-F118 HydrophobicContact CB-CZ 3.32Å; N71-S149 PolarHBondContact ND2-OG 3Å; N71-W153 PolarHBondContact OD1-NE1 3.42Å
72	L	94.7	Very high	93.5	Very high	1 Å²	1	26.6 Å²	26.6	1%	0.005	13%	0.133	C	C	.	.	H	α-helix	trans	-61.4	-44.6	172.3	-177.8	58.9	0	0	0	111.5	Y68 L70 I74 S75 D76 G115 F118 I119 L122 Y297	Y68-L72 WeakPolarHBondContact O-CB 3.49Å; Y68-L72 PolarHBondContact O-N 3.16Å; L70-L72 VanDerWaalsContact C-N 3.32Å; L70-L72 PolarHBondContact O-N 2.88Å; L72-I74 VanDerWaalsContact C-N 3.34Å; L72-I74 PolarHBondContact O-N 3.32Å; L72-S75 VanDerWaalsContact O-CB 3.31Å; L72-S75 WeakPolarHBondContact O-CB 3.19Å; L72-S75 PolarHBondContact O-N 3.27Å; L72-D76 PolarHBondContact O-N 2.7Å; L72-G115 WeakPolarHBondContact CD1-O 3.05Å; L72-F118 HydrophobicContact CB-CB 4.15Å; L72-F118 HydrophobicContact CD1-CB 4.36Å; L72-I119 HydrophobicContact CD1-CD1 4.41Å; L72-I119 HydrophobicContact CD1-CG1 4.03Å; L72-I119 HydrophobicContact CD2-CG1 4.05Å; L72-L122 HydrophobicContact CD2-CD1 3.93Å; L72-Y297 WeakPolarHBondContact CD2-OH 3.36Å
73	A	95.5	Very high	94	Very high	1 Å²	1	19 Å²	19	1%	0.008	10%	0.1	C	C	.	.	H	α-helix	trans	-64.6	-36.4	175.3	0	0	0	0	0	112.6	V51 I52 L69 L70 D76 L77	V51-A73 HydrophobicContact CB-CB 4.47Å; V51-A73 HydrophobicContact CG1-CB 4.07Å; I52-A73 HydrophobicContact CD1-CB 4.23Å; I52-A73 HydrophobicContact CG1-CB 3.8Å; L69-A73 PolarHBondContact O-N 3.24Å; L69-A73 VanDerWaalsContact O-N 3.08Å; L70-A73 PolarHBondContact O-N 3.4Å; A73-D76 PolarHBondContact O-N 3.48Å; A73-L77 WeakPolarHBondContact O-CG 3.4Å; A73-L77 PolarHBondContact O-N 3.46Å
74	I	96.8	Very high	94.4	Very high	50 Å²	50	19.7 Å²	19.7	26%	0.256	10%	0.103	S	C	.	.	H	α-helix	trans	-66	-40.9	174.1	-66.7	166.7	0	0	0	110.9	I52 L70 N71 L72 L77 F78 W153	I52-I74 HydrophobicContact CD1-CG1 4.25Å; L70-I74 HydrophobicContact CD1-CD1 4.46Å; L70-I74 HydrophobicContact CG-CD1 4.07Å; L70-I74 WeakPolarHBondContact O-CG1 3.44Å; L70-I74 PolarHBondContact O-N 3.01Å; N71-I74 PolarHBondContact O-N 2.97Å; L72-I74 VanDerWaalsContact C-N 3.34Å; L72-I74 PolarHBondContact O-N 3.32Å; I74-L77 WeakPolarHBondContact O-CB 3.28Å; I74-L77 PolarHBondContact O-N 3.08Å; I74-F78 HydrophobicContact CG2-CE1 4.37Å; I74-F78 HydrophobicContact CG2-CE2 4.37Å; I74-F78 HydrophobicContact CG2-CZ 4.18Å; I74-F78 PolarHBondContact O-N 3Å; I74-W153 HydrophobicContact CB-CZ2 4.27Å; I74-W153 HydrophobicContact CG2-CH2 4Å; I74-W153 HydrophobicContact CG2-CZ2 3.79Å
75	S	97	Very high	94.7	Very high	0 Å²	0	21.9 Å²	21.9	0%	0	11%	0.112	C	C	.	.	H	α-helix	trans	-58.9	-46.6	174.3	179.8	0	0	0	0	111.9	N71 L72 L77 F78 F79 G111 S114 G115	N71-S75 WeakPolarHBondContact O-CB 3.38Å; N71-S75 PolarHBondContact O-N 3.12Å; L72-S75 VanDerWaalsContact O-CB 3.31Å; L72-S75 WeakPolarHBondContact O-CB 3.19Å; L72-S75 PolarHBondContact O-N 3.27Å; S75-L77 VanDerWaalsContact C-N 3.28Å; S75-L77 PolarHBondContact O-N 3.34Å; S75-F78 PolarHBondContact O-N 3.37Å; S75-F79 PolarHBondContact O-N 3.49Å; S75-F79 VanDerWaalsContact O-N 3.12Å; S75-G111 PolarHBondContact OG-O 3.28Å; S75-S114 WeakPolarHBondContact CB-OG 3.49Å; S75-S114 PolarHBondContact OG-OG 3.26Å; S75-G115 VanDerWaalsContact OG-CA 3.26Å; S75-G115 WeakPolarHBondContact OG-CA 3.14Å; S75-G115 PolarHBondContact OG-N 3.42Å
76	D	96	Very high	94.8	Very high	10 Å²	10	23 Å²	23	5%	0.053	12%	0.115	C	C	.	.	H	α-helix	trans	-61.9	-36.8	175.5	-71	-33.1	0	0	0	111.3	L72 A73 F79 L80 C290 N293	L72-D76 PolarHBondContact O-N 2.7Å; A73-D76 PolarHBondContact O-N 3.48Å; D76-F79 WeakPolarHBondContact O-CB 3.45Å; D76-F79 PolarHBondContact O-N 3.47Å; D76-L80 WeakPolarHBondContact O-CB 3.46Å; D76-L80 WeakPolarHBondContact O-CD1 3.47Å; D76-L80 WeakPolarHBondContact O-CG 3.25Å; D76-L80 PolarHBondContact O-N 2.89Å; D76-C290 HydrophobicContact CB-CB 4.47Å; D76-N293 PolarHBondContact OD2-ND2 3.01Å
77	L	96.2	Very high	95	Very high	17 Å²	17	22.5 Å²	22.5	9%	0.089	11%	0.114	C	C	.	.	H	α-helix	trans	-65.2	-42.8	174.6	-73.4	177.7	0	0	0	112.8	F45 N48 M49 I52 A73 I74 S75 F79 L80 L81	F45-L77 HydrophobicContact CD2-CD2 3.96Å; F45-L77 HydrophobicContact CE2-CD2 4.37Å; N48-L77 HydrophobicContact CB-CD2 3.97Å; N48-L77 HydrophobicContact CB-CG 4.11Å; M49-L77 HydrophobicContact CE-CD1 3.45Å; M49-L77 VanDerWaalsContact CE-CD1 3.45Å; M49-L77 HydrophobicContact CE-CD2 3.91Å; M49-L77 HydrophobicContact CE-CG 4.34Å; M49-L77 HydrophobicContact CG-CD2 4.42Å; M49-L77 HydrophobicContact SD-CD1 3.91Å; I52-L77 HydrophobicContact CD1-CD1 3.36Å; I52-L77 HydrophobicContact CD1-CG 4.41Å; A73-L77 WeakPolarHBondContact O-CG 3.4Å; A73-L77 PolarHBondContact O-N 3.46Å; I74-L77 WeakPolarHBondContact O-CB 3.28Å; I74-L77 PolarHBondContact O-N 3.08Å; S75-L77 VanDerWaalsContact C-N 3.28Å; S75-L77 PolarHBondContact O-N 3.34Å; L77-F79 VanDerWaalsContact C-N 3.25Å; L77-F79 PolarHBondContact O-N 3.25Å; L77-L80 HydrophobicContact CD2-CD1 4.23Å; L77-L80 PolarHBondContact O-N 3.33Å; L77-L81 VanDerWaalsContact O-CG 3.28Å; L77-L81 WeakPolarHBondContact O-CG 3.43Å; L77-L81 PolarHBondContact O-N 2.89Å
78	F	95.9	Very high	94.9	Very high	67 Å²	67	25.4 Å²	25.4	29%	0.294	13%	0.127	S	C	.	.	H	α-helix	trans	-59	-40.6	174.6	-74.4	-11.1	0	0	0	111.8	I74 S75 L81 L107 I110 W153	I74-F78 HydrophobicContact CG2-CE1 4.37Å; I74-F78 HydrophobicContact CG2-CE2 4.37Å; I74-F78 HydrophobicContact CG2-CZ 4.18Å; I74-F78 PolarHBondContact O-N 3Å; S75-F78 PolarHBondContact O-N 3.37Å; F78-L81 HydrophobicContact CD1-CD1 4.45Å; F78-L107 HydrophobicContact CB-CD2 4.44Å; F78-L107 HydrophobicContact CD1-CD2 4.49Å; F78-L107 HydrophobicContact CG-CD2 4.31Å; F78-I110 HydrophobicContact CD2-CG2 4.03Å; F78-W153 AromaticContact CD2-CH2 3.56Å; F78-W153 HydrophobicContact CD2-CH2 3.56Å; F78-W153 AromaticContact CD2-CZ3 3.55Å; F78-W153 HydrophobicContact CD2-CZ3 3.55Å; F78-W153 HydrophobicContact CE2-CE3 4.32Å; F78-W153 AromaticContact CE2-CH2 3.46Å; F78-W153 HydrophobicContact CE2-CH2 3.46Å; F78-W153 VanDerWaalsContact CE2-CH2 3.46Å; F78-W153 HydrophobicContact CE2-CZ2 4.41Å; F78-W153 AromaticContact CE2-CZ3 3.41Å; F78-W153 HydrophobicContact CE2-CZ3 3.41Å; F78-W153 VanDerWaalsContact CE2-CZ3 3.41Å; F78-W153 HydrophobicContact CZ-CH2 4.49Å
79	F	94.6	Very high	94.8	Very high	7 Å²	7	28 Å²	28	3%	0.031	14%	0.137	C	C	.	.	H	α-helix	trans	-63.5	-49.3	173.6	-165.4	-87	0	0	0	111.4	S75 D76 L77 L81 T82 V83 Y108 W248 M287 C290	S75-F79 PolarHBondContact O-N 3.49Å; S75-F79 VanDerWaalsContact O-N 3.12Å; D76-F79 WeakPolarHBondContact O-CB 3.45Å; D76-F79 PolarHBondContact O-N 3.47Å; L77-F79 VanDerWaalsContact C-N 3.25Å; L77-F79 PolarHBondContact O-N 3.25Å; F79-L81 VanDerWaalsContact C-N 3.32Å; F79-L81 PolarHBondContact O-N 2.88Å; F79-T82 PolarHBondContact O-N 3.48Å; F79-T82 PolarHBondContact O-OG1 2.98Å; F79-V83 HydrophobicContact CD1-CG2 4.31Å; F79-V83 HydrophobicContact CE1-CG2 4.4Å; F79-Y108 HydrophobicContact CD2-CD2 4.02Å; F79-Y108 HydrophobicContact CD2-CE2 4.31Å; F79-Y108 HydrophobicContact CE1-CE2 4.49Å; F79-Y108 AromaticContact CE2-CD2 3.36Å; F79-Y108 HydrophobicContact CE2-CD2 3.36Å; F79-Y108 AromaticContact CE2-CE2 3.23Å; F79-Y108 HydrophobicContact CE2-CE2 3.23Å; F79-Y108 HydrophobicContact CE2-CG 4.13Å; F79-Y108 AromaticContact CE2-CZ 3.89Å; F79-Y108 AromaticContact CZ-CD2 3.76Å; F79-Y108 HydrophobicContact CZ-CD2 3.76Å; F79-Y108 AromaticContact CZ-CE2 3.36Å; F79-Y108 HydrophobicContact CZ-CE2 3.36Å; F79-W248 HydrophobicContact CE2-CH2 4.01Å; F79-W248 HydrophobicContact CE2-CZ2 4.18Å; F79-W248 AromaticContact CZ-CH2 3.95Å; F79-W248 HydrophobicContact CZ-CH2 3.95Å; F79-W248 HydrophobicContact CZ-CZ2 4.09Å; F79-M287 HydrophobicContact CE1-CB 4.16Å; F79-M287 HydrophobicContact CE1-CG 4.25Å; F79-M287 HydrophobicContact CE1-SD 4.35Å; F79-M287 HydrophobicContact CZ-CB 4.4Å; F79-M287 HydrophobicContact CZ-CG 4.09Å; F79-M287 HydrophobicContact CZ-SD 4.33Å; F79-C290 HydrophobicContact CD1-CB 3.93Å
80	L	95.8	Very high	94.6	Very high	0 Å²	0	28.1 Å²	28.1	0%	0	14%	0.141	C	C	.	.	H	α-helix	trans	-59.7	-36.4	-179.7	-78.1	161.5	0	0	0	113.4	V40 F41 G44 D76 L77 T82 V83 P84 C290	V40-L80 HydrophobicContact CG1-CD2 4.29Å; F41-L80 HydrophobicContact CD2-CB 4.47Å; F41-L80 VanDerWaalsContact CD2-O 3.3Å; F41-L80 WeakPolarHBondContact CD2-O 3.33Å; G44-L80 WeakPolarHBondContact O-CD1 3.34Å; D76-L80 WeakPolarHBondContact O-CB 3.46Å; D76-L80 WeakPolarHBondContact O-CD1 3.47Å; D76-L80 WeakPolarHBondContact O-CG 3.25Å; D76-L80 PolarHBondContact O-N 2.89Å; L77-L80 HydrophobicContact CD2-CD1 4.23Å; L77-L80 PolarHBondContact O-N 3.33Å; L80-T82 PolarHBondContact O-N 2.9Å; L80-T82 VanDerWaalsContact O-N 3.15Å; L80-V83 WeakPolarHBondContact O-CB 3.3Å; L80-V83 PolarHBondContact O-N 2.83Å; L80-V83 VanDerWaalsContact O-N 3.09Å; L80-P84 VanDerWaalsContact O-CD 3.28Å; L80-P84 WeakPolarHBondContact O-CD 3.43Å; L80-C290 HydrophobicContact CD2-CB 4.48Å; L80-C290 WeakPolarHBondContact CD2-SG 3.35Å; L80-C290 HydrophobicContact CG-CB 4.21Å
81	L	95.8	Very high	94.3	Very high	81 Å²	81	29.5 Å²	29.5	42%	0.424	16%	0.156	S	C	.	.	H	α-helix	trans	-60.4	-23.8	177.1	-73	172.1	0	0	0	112.7	L77 F78 F79 F85	L77-L81 VanDerWaalsContact O-CG 3.28Å; L77-L81 WeakPolarHBondContact O-CG 3.43Å; L77-L81 PolarHBondContact O-N 2.89Å; F78-L81 HydrophobicContact CD1-CD1 4.45Å; F79-L81 VanDerWaalsContact C-N 3.32Å; F79-L81 PolarHBondContact O-N 2.88Å; L81-F85 WeakPolarHBondContact O-CD2 3.25Å; L81-F85 WeakPolarHBondContact O-CE2 3.5Å
82	T	95.3	Very high	93.9	Very high	0 Å²	0	31 Å²	31	0%	0	17%	0.171	C	C	.	.	H	α-helix	trans	-85	-24.5	177.4	74.3	0	0	0	0	113.4	F79 L80 F85 W86 L104 L107	F79-T82 PolarHBondContact O-N 3.48Å; F79-T82 PolarHBondContact O-OG1 2.98Å; L80-T82 PolarHBondContact O-N 2.9Å; L80-T82 VanDerWaalsContact O-N 3.15Å; T82-F85 WeakPolarHBondContact O-CB 3.28Å; T82-F85 PolarHBondContact O-N 3.25Å; T82-W86 PolarHBondContact O-N 3.4Å; T82-W86 PolarHBondContact OG1-NE1 3.39Å; T82-L104 HydrophobicContact CG2-CB 4.43Å; T82-L104 HydrophobicContact CG2-CD2 3.98Å; T82-L104 WeakPolarHBondContact CG2-O 3.49Å; T82-L107 HydrophobicContact CG2-CB 3.55Å; T82-L107 HydrophobicContact CG2-CD1 4.48Å
83	V	94.7	Very high	93.6	Very high	0 Å²	0	33.4 Å²	33.4	0%	0	18%	0.182	C	C	.	.	H	α-helix	trans	-57.5	-42.8	-172.2	175.2	0	0	0	0	113.7	Y37 F41 F79 L80 F85 W86 A87	Y37-V83 HydrophobicContact CG-CG1 4.02Å; Y37-V83 WeakPolarHBondContact O-CG1 3.35Å; F41-V83 HydrophobicContact CB-CG1 4.39Å; F79-V83 HydrophobicContact CD1-CG2 4.31Å; F79-V83 HydrophobicContact CE1-CG2 4.4Å; L80-V83 WeakPolarHBondContact O-CB 3.3Å; L80-V83 PolarHBondContact O-N 2.83Å; L80-V83 VanDerWaalsContact O-N 3.09Å; V83-F85 VanDerWaalsContact C-N 3.26Å; V83-F85 PolarHBondContact O-N 3.32Å; V83-W86 PolarHBondContact O-N 3.48Å; V83-A87 WeakPolarHBondContact O-CB 3.49Å; V83-A87 PolarHBondContact O-N 3.4Å
84	P	94.7	Very high	93.4	Very high	54 Å²	54	33.5 Å²	33.5	35%	0.351	18%	0.182	S	C	.	.	H	α-helix	trans	-60.3	-34.2	176.9	-25.6	35.4	0	0	0	113.7	F41 L80 A87 H88	F41-P84 HydrophobicContact CD1-CG 4.36Å; F41-P84 HydrophobicContact CD2-CG 3.67Å; F41-P84 HydrophobicContact CE1-CG 4.48Å; F41-P84 HydrophobicContact CE2-CG 3.81Å; F41-P84 HydrophobicContact CG-CG 3.95Å; F41-P84 HydrophobicContact CZ-CG 4.22Å; L80-P84 VanDerWaalsContact O-CD 3.28Å; L80-P84 WeakPolarHBondContact O-CD 3.43Å; P84-A87 WeakPolarHBondContact O-CB 3.31Å; P84-A87 PolarHBondContact O-N 2.86Å; P84-H88 PolarHBondContact O-N 3.39Å
85	F	94.6	Very high	93.2	Very high	51 Å²	51	35.3 Å²	35.3	22%	0.224	19%	0.193	C	C	.	.	H	α-helix	trans	-72.3	-39.9	178.5	-61.6	-90	0	0	0	111.2	L81 T82 V83 A87 H88 Y89 F96 M100 L104	L81-F85 WeakPolarHBondContact O-CD2 3.25Å; L81-F85 WeakPolarHBondContact O-CE2 3.5Å; T82-F85 WeakPolarHBondContact O-CB 3.28Å; T82-F85 PolarHBondContact O-N 3.25Å; V83-F85 VanDerWaalsContact C-N 3.26Å; V83-F85 PolarHBondContact O-N 3.32Å; F85-A87 VanDerWaalsContact C-N 3.29Å; F85-A87 PolarHBondContact O-N 3.01Å; F85-H88 PolarHBondContact O-N 2.9Å; F85-Y89 WeakPolarHBondContact O-CB 3.5Å; F85-Y89 PolarHBondContact O-N 2.99Å; F85-F96 HydrophobicContact CB-CE2 4.3Å; F85-F96 AromaticContact CD1-CD1 3.91Å; F85-F96 HydrophobicContact CD1-CD1 3.91Å; F85-F96 AromaticContact CD1-CD2 3.95Å; F85-F96 HydrophobicContact CD1-CD2 3.95Å; F85-F96 AromaticContact CD1-CE1 3.71Å; F85-F96 HydrophobicContact CD1-CE1 3.71Å; F85-F96 AromaticContact CD1-CE2 3.75Å; F85-F96 HydrophobicContact CD1-CE2 3.75Å; F85-F96 HydrophobicContact CD1-CG 4.03Å; F85-F96 AromaticContact CD1-CZ 3.63Å; F85-F96 HydrophobicContact CD1-CZ 3.63Å; F85-F96 AromaticContact CE1-CD1 3.99Å; F85-F96 HydrophobicContact CE1-CD1 3.99Å; F85-F96 AromaticContact CE1-CE1 3.87Å; F85-F96 HydrophobicContact CE1-CE1 3.87Å; F85-F96 HydrophobicContact CE1-CG 4.47Å; F85-F96 HydrophobicContact CE1-CZ 4.23Å; F85-M100 HydrophobicContact CD1-CE 4.44Å; F85-M100 HydrophobicContact CE1-CE 3.53Å; F85-M100 HydrophobicContact CE2-CE 4.49Å; F85-M100 HydrophobicContact CZ-CE 3.56Å; F85-L104 HydrophobicContact CB-CD1 3.52Å; F85-L104 HydrophobicContact CD1-CD1 3.63Å; F85-L104 HydrophobicContact CD2-CD1 3.84Å; F85-L104 HydrophobicContact CD2-CD2 3.67Å; F85-L104 HydrophobicContact CD2-CG 4.44Å; F85-L104 HydrophobicContact CE1-CD1 4.3Å; F85-L104 HydrophobicContact CE2-CD1 4.47Å; F85-L104 HydrophobicContact CE2-CD2 3.95Å; F85-L104 HydrophobicContact CG-CD1 3.37Å; F85-L104 HydrophobicContact CG-CD2 4.12Å; F85-L104 HydrophobicContact CG-CG 4.42Å
86	W	93	Very high	93	Very high	35 Å²	35	38.7 Å²	38.7	13%	0.133	21%	0.207	C	C	.	.	H	α-helix	trans	-65.9	-32.6	172.5	-59.8	123.1	0	0	0	112.4	Y37 T82 V83 Y89 A90 W94 M287	Y37-W86 HydrophobicContact CD2-CB 4.27Å; Y37-W86 HydrophobicContact CE2-CB 4.08Å; T82-W86 PolarHBondContact O-N 3.4Å; T82-W86 PolarHBondContact OG1-NE1 3.39Å; V83-W86 PolarHBondContact O-N 3.48Å; W86-Y89 HydrophobicContact CE3-CD1 4.02Å; W86-Y89 HydrophobicContact CZ3-CD1 4.26Å; W86-Y89 PolarHBondContact O-N 3.44Å; W86-A90 WeakPolarHBondContact O-CB 3.39Å; W86-A90 PolarHBondContact O-N 2.86Å; W86-W94 HydrophobicContact CE3-CZ3 4.27Å; W86-W94 HydrophobicContact CH2-CZ3 4.4Å; W86-W94 AromaticContact CZ3-CZ3 3.93Å; W86-W94 HydrophobicContact CZ3-CZ3 3.93Å; W86-M287 HydrophobicContact CG-CE 4.33Å
87	A	92.4	Very high	92.8	Very high	7 Å²	7	39.8 Å²	39.8	6%	0.058	22%	0.221	C	C	.	.	H	α-helix	trans	-64.4	-46.9	173.5	0	0	0	0	0	111.5	Y37 V83 P84 F85 A90 A91	Y37-A87 HydrophobicContact CD2-CB 4.11Å; Y37-A87 HydrophobicContact CG-CB 4.48Å; V83-A87 WeakPolarHBondContact O-CB 3.49Å; V83-A87 PolarHBondContact O-N 3.4Å; P84-A87 WeakPolarHBondContact O-CB 3.31Å; P84-A87 PolarHBondContact O-N 2.86Å; F85-A87 VanDerWaalsContact C-N 3.29Å; F85-A87 PolarHBondContact O-N 3.01Å; A87-A90 PolarHBondContact O-N 3.37Å; A87-A91 PolarHBondContact O-N 3.27Å; A87-A91 VanDerWaalsContact O-N 3.14Å
88	H	93.4	Very high	92.6	Very high	73 Å²	73	41.8 Å²	41.8	34%	0.338	23%	0.232	S	C	.	.	H	α-helix	trans	-62.5	-45.2	174.2	-177.7	77.9	0	0	0	111.7	P84 F85 A90 A91 A92 D95 F96	P84-H88 PolarHBondContact O-N 3.39Å; F85-H88 PolarHBondContact O-N 2.9Å; H88-A90 VanDerWaalsContact C-N 3.28Å; H88-A90 PolarHBondContact O-N 2.87Å; H88-A91 PolarHBondContact O-N 3.05Å; H88-A91 VanDerWaalsContact O-N 3.08Å; H88-A92 PolarHBondContact O-N 3.49Å; H88-D95 IonicContact CD2-OD2 3.86Å; H88-D95 IonicContact CE1-OD2 3.78Å; H88-D95 IonicContact NE2-OD2 2.86Å; H88-D95 PolarHBondContact NE2-OD2 3.43Å; H88-F96 HydrophobicContact CB-CE2 4.26Å; H88-F96 HydrophobicContact CB-CZ 4.15Å; H88-F96 AromaticContact CD2-CE2 3.62Å; H88-F96 AromaticContact CD2-CZ 3.67Å; H88-F96 AromaticContact CG-CZ 3.98Å
89	Y	91.1	Very high	92.5	Very high	70 Å²	70	44 Å²	44	28%	0.275	25%	0.251	S	S	.	.	H	α-helix	trans	-58.8	-39.6	178.3	178.8	-121	0	0	0	112.4	F85 W86 W94	F85-Y89 WeakPolarHBondContact O-CB 3.5Å; F85-Y89 PolarHBondContact O-N 2.99Å; W86-Y89 HydrophobicContact CE3-CD1 4.02Å; W86-Y89 HydrophobicContact CZ3-CD1 4.26Å; W86-Y89 PolarHBondContact O-N 3.44Å; Y89-W94 HydrophobicContact CD2-CB 3.9Å; Y89-W94 AromaticContact CD2-CE3 3.84Å; Y89-W94 HydrophobicContact CD2-CE3 3.84Å; Y89-W94 HydrophobicContact CE2-CB 3.93Å; Y89-W94 HydrophobicContact CE2-CE3 4.47Å; Y89-W94 HydrophobicContact CG-CE3 4Å
90	A	87.9	Confident	92.5	Very high	23 Å²	23	46.3 Å²	46.3	19%	0.19	26%	0.262	C	S	.	.	H	α-helix	trans	-67.6	-36.6	175.4	0	0	0	0	0	112.8	A30 L33 W86 A87 H88	A30-A90 VanDerWaalsContact CA-O 3.23Å; A30-A90 WeakPolarHBondContact CA-O 3.32Å; A30-A90 WeakPolarHBondContact CB-O 3.18Å; L33-A90 HydrophobicContact CB-CB 3.89Å; L33-A90 HydrophobicContact CD1-CB 3.89Å; W86-A90 WeakPolarHBondContact O-CB 3.39Å; W86-A90 PolarHBondContact O-N 2.86Å; A87-A90 PolarHBondContact O-N 3.37Å; H88-A90 VanDerWaalsContact C-N 3.28Å; H88-A90 PolarHBondContact O-N 2.87Å
91	A	87.7	Confident	92.4	Very high	54 Å²	54	46.3 Å²	46.3	45%	0.446	26%	0.262	S	S	.	.	H	α-helix	trans	-73.9	-35.8	-179.7	0	0	0	0	0	113.1	P34 A87 H88	P34-A91 HydrophobicContact CB-CB 4.44Å; P34-A91 HydrophobicContact CG-CB 3.69Å; A87-A91 PolarHBondContact O-N 3.27Å; A87-A91 VanDerWaalsContact O-N 3.14Å; H88-A91 PolarHBondContact O-N 3.05Å; H88-A91 VanDerWaalsContact O-N 3.08Å
92	A	88.4	Confident	92.3	Very high	50 Å²	50	45.1 Å²	45.1	41%	0.413	26%	0.255	S	S	.	.	S	Bend	trans	-134.1	-108.3	-171.7	0	0	0	0	0	111.4	H88	H88-A92 PolarHBondContact O-N 3.49Å
93	Q	88.5	Confident	92.4	Very high	52 Å²	52	50 Å²	50	24%	0.243	28%	0.28	C	S	.	.			trans	-147.6	179.8	-177.7	69.2	-176.6	2	0	0	110.2	D95 H175	Q93-D95 WeakPolarHBondContact CG-OD1 3.26Å; Q93-D95 PolarHBondContact NE2-OD1 3.08Å; Q93-D95 PolarHBondContact O-N 3.12Å; Q93-H175 HydrophobicContact CB-CB 4.32Å; Q93-H175 PolarHBondContact OE1-ND1 3.1Å; Q93-H175 VanDerWaalsContact OE1-ND1 3.11Å
94	W	92.4	Very high	92.4	Very high	3 Å²	3	50.1 Å²	50.1	1%	0.011	28%	0.281	C	S	.	.			trans	-83.8	96.3	177.9	-169.5	-93.9	0	0	0	112.4	W86 Y89 F96 G97 M100 C101 L104 Y176 C178	W86-W94 HydrophobicContact CE3-CZ3 4.27Å; W86-W94 HydrophobicContact CH2-CZ3 4.4Å; W86-W94 AromaticContact CZ3-CZ3 3.93Å; W86-W94 HydrophobicContact CZ3-CZ3 3.93Å; Y89-W94 HydrophobicContact CD2-CB 3.9Å; Y89-W94 AromaticContact CD2-CE3 3.84Å; Y89-W94 HydrophobicContact CD2-CE3 3.84Å; Y89-W94 HydrophobicContact CE2-CB 3.93Å; Y89-W94 HydrophobicContact CE2-CE3 4.47Å; Y89-W94 HydrophobicContact CG-CE3 4Å; W94-F96 HydrophobicContact CD2-CD2 4.27Å; W94-F96 HydrophobicContact CE3-CD2 4.3Å; W94-F96 HydrophobicContact CH2-CD2 4.21Å; W94-F96 HydrophobicContact CZ2-CB 3.93Å; W94-F96 HydrophobicContact CZ2-CD2 4.09Å; W94-F96 HydrophobicContact CZ2-CG 4.47Å; W94-F96 HydrophobicContact CZ3-CD2 4.3Å; W94-G97 PolarHBondContact NE1-O 3.49Å; W94-M100 HydrophobicContact CZ2-CB 4.43Å; W94-C101 HydrophobicContact CH2-CB 4.45Å; W94-C101 HydrophobicContact CZ2-CB 3.61Å; W94-L104 HydrophobicContact CH2-CD1 3.58Å; W94-L104 HydrophobicContact CZ2-CD1 4.11Å; W94-Y176 VanDerWaalsContact CB-O 3.3Å; W94-Y176 WeakPolarHBondContact CB-O 3.4Å; W94-Y176 PolarHBondContact N-O 3.07Å; W94-Y176 WeakPolarHBondContact O-CB 3.29Å; W94-C178 HydrophobicContact CB-CB 4.45Å; W94-C178 HydrophobicContact CD2-CB 3.48Å; W94-C178 VanDerWaalsContact CD2-CB 3.48Å; W94-C178 HydrophobicContact CE3-CB 3.61Å; W94-C178 HydrophobicContact CG-CB 3.84Å; W94-C178 HydrophobicContact CH2-CB 4.41Å; W94-C178 HydrophobicContact CZ2-CB 4.38Å; W94-C178 HydrophobicContact CZ3-CB 4.07Å
95	D	92.4	Very high	92.4	Very high	88 Å²	88	47.9 Å²	47.9	47%	0.471	27%	0.266	S	S	.	.			trans	-95.8	-2.6	-178	-58.9	-51.4	0	0	0	114.1	H88 Q93	H88-D95 IonicContact CD2-OD2 3.86Å; H88-D95 IonicContact CE1-OD2 3.78Å; H88-D95 IonicContact NE2-OD2 2.86Å; H88-D95 PolarHBondContact NE2-OD2 3.43Å; Q93-D95 WeakPolarHBondContact CG-OD1 3.26Å; Q93-D95 PolarHBondContact NE2-OD1 3.08Å; Q93-D95 PolarHBondContact O-N 3.12Å
96	F	91.4	Very high	92.5	Very high	71 Å²	71	45.7 Å²	45.7	31%	0.311	26%	0.258	S	S	.	.	S	Bend	trans	-91.3	0.2	-169.8	-52	-75.4	0	0	0	114.8	F85 H88 W94 M100	F85-F96 HydrophobicContact CB-CE2 4.3Å; F85-F96 AromaticContact CD1-CD1 3.91Å; F85-F96 HydrophobicContact CD1-CD1 3.91Å; F85-F96 AromaticContact CD1-CD2 3.95Å; F85-F96 HydrophobicContact CD1-CD2 3.95Å; F85-F96 AromaticContact CD1-CE1 3.71Å; F85-F96 HydrophobicContact CD1-CE1 3.71Å; F85-F96 AromaticContact CD1-CE2 3.75Å; F85-F96 HydrophobicContact CD1-CE2 3.75Å; F85-F96 HydrophobicContact CD1-CG 4.03Å; F85-F96 AromaticContact CD1-CZ 3.63Å; F85-F96 HydrophobicContact CD1-CZ 3.63Å; F85-F96 AromaticContact CE1-CD1 3.99Å; F85-F96 HydrophobicContact CE1-CD1 3.99Å; F85-F96 AromaticContact CE1-CE1 3.87Å; F85-F96 HydrophobicContact CE1-CE1 3.87Å; F85-F96 HydrophobicContact CE1-CG 4.47Å; F85-F96 HydrophobicContact CE1-CZ 4.23Å; H88-F96 HydrophobicContact CB-CE2 4.26Å; H88-F96 HydrophobicContact CB-CZ 4.15Å; H88-F96 AromaticContact CD2-CE2 3.62Å; H88-F96 AromaticContact CD2-CZ 3.67Å; H88-F96 AromaticContact CG-CZ 3.98Å; W94-F96 HydrophobicContact CD2-CD2 4.27Å; W94-F96 HydrophobicContact CE3-CD2 4.3Å; W94-F96 HydrophobicContact CH2-CD2 4.21Å; W94-F96 HydrophobicContact CZ2-CB 3.93Å; W94-F96 HydrophobicContact CZ2-CD2 4.09Å; W94-F96 HydrophobicContact CZ2-CG 4.47Å; W94-F96 HydrophobicContact CZ3-CD2 4.3Å; F96-M100 HydrophobicContact CB-CB 3.69Å; F96-M100 HydrophobicContact CB-CG 3.76Å; F96-M100 HydrophobicContact CG-CG 4.47Å; F96-M100 VanDerWaalsContact O-CB 3.22Å; F96-M100 WeakPolarHBondContact O-CB 3.28Å
97	G	92.3	Very high	92.7	Very high	33 Å²	33	45.9 Å²	45.9	34%	0.34	26%	0.261	S	S	.	.	H	α-helix	trans	73.2	177	-179.5	0	0	0	0	0	114.7	W94 C101	W94-G97 PolarHBondContact NE1-O 3.49Å; G97-C101 PolarHBondContact O-N 3.42Å
98	N	92.7	Very high	92.8	Very high	59 Å²	59	46.2 Å²	46.2	32%	0.316	26%	0.261	S	S	.	.	H	α-helix	trans	-70.2	-39.1	-171.7	-176.4	74	0	0	0	113.9	M100 C101 Q102 R168 S169	N98-M100 VanDerWaalsContact C-N 3.35Å; N98-M100 PolarHBondContact O-N 3.34Å; N98-C101 WeakPolarHBondContact O-CB 3.47Å; N98-C101 PolarHBondContact O-N 3.36Å; N98-Q102 PolarHBondContact O-N 2.92Å; N98-R168 VanDerWaalsContact OD1-CA 3.28Å; N98-R168 WeakPolarHBondContact OD1-CA 3.28Å; N98-S169 PolarHBondContact OD1-N 3.12Å
99	T	93.1	Very high	92.9	Very high	113 Å²	113	43.8 Å²	43.8	69%	0.693	25%	0.25	S	C	*	.	H	α-helix	trans	-62.1	-43.7	-178.8	48.5	0	0	0	0	111.5	Q102 L103	T99-Q102 PolarHBondContact O-N 3.4Å; T99-L103 WeakPolarHBondContact O-CB 3.3Å; T99-L103 PolarHBondContact O-N 3.24Å
100	M	94.1	Very high	93.2	Very high	55 Å²	55	41.6 Å²	41.6	27%	0.271	24%	0.242	S	C	.	.	H	α-helix	trans	-69.1	-35.1	177.5	-160	62.7	145.4	0	0	111.8	F85 W94 F96 N98 L103 L104	F85-M100 HydrophobicContact CD1-CE 4.44Å; F85-M100 HydrophobicContact CE1-CE 3.53Å; F85-M100 HydrophobicContact CE2-CE 4.49Å; F85-M100 HydrophobicContact CZ-CE 3.56Å; W94-M100 HydrophobicContact CZ2-CB 4.43Å; F96-M100 HydrophobicContact CB-CB 3.69Å; F96-M100 HydrophobicContact CB-CG 3.76Å; F96-M100 HydrophobicContact CG-CG 4.47Å; F96-M100 VanDerWaalsContact O-CB 3.22Å; F96-M100 WeakPolarHBondContact O-CB 3.28Å; N98-M100 VanDerWaalsContact C-N 3.35Å; N98-M100 PolarHBondContact O-N 3.34Å; M100-L103 PolarHBondContact O-N 3.42Å; M100-L103 HydrophobicContact SD-CD2 4.1Å; M100-L104 HydrophobicContact CG-CD1 3.64Å; M100-L104 HydrophobicContact CG-CG 4.08Å; M100-L104 VanDerWaalsContact O-CB 3.29Å; M100-L104 WeakPolarHBondContact O-CB 3.44Å; M100-L104 VanDerWaalsContact O-CG 3.22Å; M100-L104 WeakPolarHBondContact O-CG 3.21Å; M100-L104 PolarHBondContact O-N 2.86Å; M100-L104 HydrophobicContact SD-CD1 4.41Å; M100-L104 HydrophobicContact SD-CG 4.34Å
101	C	94.6	Very high	93.6	Very high	0 Å²	0	40.7 Å²	40.7	0%	0	24%	0.235	C	C	.	.	H	α-helix	trans	-58.9	-50.3	174.9	173	0	0	0	0	110.3	W94 G97 N98 L103 L104 T105 T167 C178	W94-C101 HydrophobicContact CH2-CB 4.45Å; W94-C101 HydrophobicContact CZ2-CB 3.61Å; G97-C101 PolarHBondContact O-N 3.42Å; N98-C101 WeakPolarHBondContact O-CB 3.47Å; N98-C101 PolarHBondContact O-N 3.36Å; C101-L103 PolarHBondContact O-N 3.22Å; C101-L104 PolarHBondContact O-N 3.33Å; C101-T105 VanDerWaalsContact O-CB 3.29Å; C101-T105 WeakPolarHBondContact O-CB 3.34Å; C101-T105 PolarHBondContact O-N 3.42Å; C101-T105 PolarHBondContact O-OG1 2.92Å; C101-T167 WeakPolarHBondContact SG-CG2 3.34Å; C101-C178 VanDerWaalsContact CA-SG 3.6Å; C101-C178 HydrophobicContact CB-CB 3.95Å; C101-C178 WeakPolarHBondContact CB-SG 3.49Å; C101-C178 VanDerWaalsContact SG-CA 3.59Å; C101-C178 WeakPolarHBondContact SG-CB 3.29Å; C101-C178 CovalentContact SG-SG 2.03Å; C101-C178 PolarHBondContact SG-SG 3.42Å
102	Q	94.7	Very high	93.9	Very high	56 Å²	56	38.5 Å²	38.5	26%	0.262	22%	0.216	S	C	.	.	H	α-helix	trans	-62.7	-43	177.6	-69.6	-179.9	-30.5	0	0	113	N98 T99 G106 I164 T167	N98-Q102 PolarHBondContact O-N 2.92Å; T99-Q102 PolarHBondContact O-N 3.4Å; Q102-G106 PolarHBondContact O-N 3.38Å; Q102-I164 HydrophobicContact CB-CG2 4.2Å; Q102-T167 WeakPolarHBondContact CG-O 3.37Å; Q102-T167 PolarHBondContact NE2-O 3.18Å
103	L	95.5	Very high	94.3	Very high	102 Å²	102	36.1 Å²	36.1	53%	0.534	20%	0.196	S	C	.	.	H	α-helix	trans	-64	-48.4	178.8	179.9	64.2	0	0	0	111.9	T99 M100 C101 G106 L107	T99-L103 WeakPolarHBondContact O-CB 3.3Å; T99-L103 PolarHBondContact O-N 3.24Å; M100-L103 PolarHBondContact O-N 3.42Å; M100-L103 HydrophobicContact SD-CD2 4.1Å; C101-L103 PolarHBondContact O-N 3.22Å; L103-G106 WeakPolarHBondContact O-CA 3.27Å; L103-G106 PolarHBondContact O-N 2.75Å; L103-G106 VanDerWaalsContact O-N 3.16Å; L103-L107 HydrophobicContact CG-CD1 4.39Å; L103-L107 PolarHBondContact O-N 2.99Å
104	L	95.8	Very high	94.7	Very high	4 Å²	4	33.7 Å²	33.7	2%	0.021	18%	0.184	C	C	.	.	H	α-helix	trans	-69	-39	-177.9	-68.7	172.1	0	0	0	111.6	T82 F85 W94 M100 C101 G106 L107 Y108	T82-L104 HydrophobicContact CG2-CB 4.43Å; T82-L104 HydrophobicContact CG2-CD2 3.98Å; T82-L104 WeakPolarHBondContact CG2-O 3.49Å; F85-L104 HydrophobicContact CB-CD1 3.52Å; F85-L104 HydrophobicContact CD1-CD1 3.63Å; F85-L104 HydrophobicContact CD2-CD1 3.84Å; F85-L104 HydrophobicContact CD2-CD2 3.67Å; F85-L104 HydrophobicContact CD2-CG 4.44Å; F85-L104 HydrophobicContact CE1-CD1 4.3Å; F85-L104 HydrophobicContact CE2-CD1 4.47Å; F85-L104 HydrophobicContact CE2-CD2 3.95Å; F85-L104 HydrophobicContact CG-CD1 3.37Å; F85-L104 HydrophobicContact CG-CD2 4.12Å; F85-L104 HydrophobicContact CG-CG 4.42Å; W94-L104 HydrophobicContact CH2-CD1 3.58Å; W94-L104 HydrophobicContact CZ2-CD1 4.11Å; M100-L104 HydrophobicContact CG-CD1 3.64Å; M100-L104 HydrophobicContact CG-CG 4.08Å; M100-L104 VanDerWaalsContact O-CB 3.29Å; M100-L104 WeakPolarHBondContact O-CB 3.44Å; M100-L104 VanDerWaalsContact O-CG 3.22Å; M100-L104 WeakPolarHBondContact O-CG 3.21Å; M100-L104 PolarHBondContact O-N 2.86Å; M100-L104 HydrophobicContact SD-CD1 4.41Å; M100-L104 HydrophobicContact SD-CG 4.34Å; C101-L104 PolarHBondContact O-N 3.33Å; L104-G106 VanDerWaalsContact C-N 3.28Å; L104-G106 PolarHBondContact O-N 3.09Å; L104-L107 PolarHBondContact O-N 3.43Å; L104-Y108 VanDerWaalsContact O-CB 3.29Å; L104-Y108 WeakPolarHBondContact O-CB 3.3Å; L104-Y108 PolarHBondContact O-N 2.81Å
105	T	94.8	Very high	94.8	Very high	7 Å²	7	33.9 Å²	33.9	4%	0.043	19%	0.187	C	C	.	.	H	α-helix	trans	-61.3	-39.1	170.1	-62.4	0	0	0	0	111.5	C101 Y108 F109 T167	C101-T105 VanDerWaalsContact O-CB 3.29Å; C101-T105 WeakPolarHBondContact O-CB 3.34Å; C101-T105 PolarHBondContact O-N 3.42Å; C101-T105 PolarHBondContact O-OG1 2.92Å; T105-Y108 PolarHBondContact O-N 2.88Å; T105-F109 HydrophobicContact CG2-CD2 3.63Å; T105-F109 HydrophobicContact CG2-CE2 3.51Å; T105-F109 VanDerWaalsContact O-CD2 3.24Å; T105-F109 WeakPolarHBondContact O-CD2 2.95Å; T105-F109 PolarHBondContact O-N 3.17Å; T105-T167 HydrophobicContact CG2-CG2 4.08Å; T105-T167 WeakPolarHBondContact OG1-CG2 3.16Å
106	G	96	Very high	94.9	Very high	4 Å²	4	29.7 Å²	29.7	4%	0.041	17%	0.165	C	C	.	.	H	α-helix	trans	-61.1	-51.9	173.7	0	0	0	0	0	112.7	Q102 L103 L104 Y108 F109 I110 I164	Q102-G106 PolarHBondContact O-N 3.38Å; L103-G106 WeakPolarHBondContact O-CA 3.27Å; L103-G106 PolarHBondContact O-N 2.75Å; L103-G106 VanDerWaalsContact O-N 3.16Å; L104-G106 VanDerWaalsContact C-N 3.28Å; L104-G106 PolarHBondContact O-N 3.09Å; G106-Y108 VanDerWaalsContact C-N 3.3Å; G106-Y108 PolarHBondContact O-N 3.38Å; G106-F109 PolarHBondContact O-N 2.95Å; G106-I110 VanDerWaalsContact O-CB 3.27Å; G106-I110 WeakPolarHBondContact O-CB 3.46Å; G106-I110 WeakPolarHBondContact O-CD1 3.2Å; G106-I110 WeakPolarHBondContact O-CG1 3.44Å; G106-I110 PolarHBondContact O-N 3.4Å; G106-I164 VanDerWaalsContact CA-CG1 3.48Å
107	L	96.7	Very high	95.2	Very high	39 Å²	39	27.4 Å²	27.4	20%	0.204	16%	0.155	C	C	.	.	H	α-helix	trans	-60.4	-39.1	177.6	-72.3	174.4	0	0	0	112.3	F78 T82 L103 L104 G111	F78-L107 HydrophobicContact CB-CD2 4.44Å; F78-L107 HydrophobicContact CD1-CD2 4.49Å; F78-L107 HydrophobicContact CG-CD2 4.31Å; T82-L107 HydrophobicContact CG2-CB 3.55Å; T82-L107 HydrophobicContact CG2-CD1 4.48Å; L103-L107 HydrophobicContact CG-CD1 4.39Å; L103-L107 PolarHBondContact O-N 2.99Å; L104-L107 PolarHBondContact O-N 3.43Å; L107-G111 PolarHBondContact O-N 2.83Å
108	Y	95.4	Very high	95.3	Very high	15 Å²	15	25.9 Å²	25.9	6%	0.059	14%	0.139	C	C	.	.	H	α-helix	trans	-59	-54	174.9	174.2	-87.8	0	0	0	111.2	F79 L104 T105 G106 G111 F112 M287	F79-Y108 HydrophobicContact CD2-CD2 4.02Å; F79-Y108 HydrophobicContact CD2-CE2 4.31Å; F79-Y108 HydrophobicContact CE1-CE2 4.49Å; F79-Y108 AromaticContact CE2-CD2 3.36Å; F79-Y108 HydrophobicContact CE2-CD2 3.36Å; F79-Y108 AromaticContact CE2-CE2 3.23Å; F79-Y108 HydrophobicContact CE2-CE2 3.23Å; F79-Y108 HydrophobicContact CE2-CG 4.13Å; F79-Y108 AromaticContact CE2-CZ 3.89Å; F79-Y108 AromaticContact CZ-CD2 3.76Å; F79-Y108 HydrophobicContact CZ-CD2 3.76Å; F79-Y108 AromaticContact CZ-CE2 3.36Å; F79-Y108 HydrophobicContact CZ-CE2 3.36Å; L104-Y108 VanDerWaalsContact O-CB 3.29Å; L104-Y108 WeakPolarHBondContact O-CB 3.3Å; L104-Y108 PolarHBondContact O-N 2.81Å; T105-Y108 PolarHBondContact O-N 2.88Å; G106-Y108 VanDerWaalsContact C-N 3.3Å; G106-Y108 PolarHBondContact O-N 3.38Å; Y108-G111 PolarHBondContact O-N 3.27Å; Y108-F112 WeakPolarHBondContact O-CB 3.26Å; Y108-F112 PolarHBondContact O-N 3.42Å; Y108-M287 HydrophobicContact CD2-CE 4.48Å; Y108-M287 HydrophobicContact CE2-CE 3.77Å; Y108-M287 HydrophobicContact CE2-SD 4.42Å
109	F	95.4	Very high	95.3	Very high	22 Å²	22	23.2 Å²	23.2	10%	0.096	13%	0.125	C	C	.	.	H	α-helix	trans	-69.8	-37.2	-179	-77.8	-60.1	0	0	0	112.7	T105 G106 F112 F113 S160 I198	T105-F109 HydrophobicContact CG2-CD2 3.63Å; T105-F109 HydrophobicContact CG2-CE2 3.51Å; T105-F109 VanDerWaalsContact O-CD2 3.24Å; T105-F109 WeakPolarHBondContact O-CD2 2.95Å; T105-F109 PolarHBondContact O-N 3.17Å; G106-F109 PolarHBondContact O-N 2.95Å; F109-F112 PolarHBondContact O-N 2.84Å; F109-F113 HydrophobicContact CB-CD2 4.23Å; F109-F113 HydrophobicContact CB-CE2 4.17Å; F109-F113 AromaticContact CD1-CE2 3.95Å; F109-F113 HydrophobicContact CD1-CE2 3.95Å; F109-F113 HydrophobicContact CG-CE2 4.39Å; F109-F113 WeakPolarHBondContact O-CD2 3.45Å; F109-F113 PolarHBondContact O-N 3.4Å; F109-S160 VanDerWaalsContact C-OG 3.24Å; F109-S160 WeakPolarHBondContact CB-OG 3.29Å; F109-I198 HydrophobicContact CE1-CD1 4.03Å
110	I	96.9	Very high	95.4	Very high	23 Å²	23	18.5 Å²	18.5	12%	0.118	10%	0.095	C	C	.	.	H	α-helix	trans	-61.2	-48	175.7	-72.7	167	0	0	0	109.3	F78 G106 F112 S114 W153 V157 S160	F78-I110 HydrophobicContact CD2-CG2 4.03Å; G106-I110 VanDerWaalsContact O-CB 3.27Å; G106-I110 WeakPolarHBondContact O-CB 3.46Å; G106-I110 WeakPolarHBondContact O-CD1 3.2Å; G106-I110 WeakPolarHBondContact O-CG1 3.44Å; G106-I110 PolarHBondContact O-N 3.4Å; I110-F112 VanDerWaalsContact C-N 3.34Å; I110-F112 PolarHBondContact O-N 2.92Å; I110-S114 VanDerWaalsContact O-CB 3.25Å; I110-S114 WeakPolarHBondContact O-CB 3Å; I110-S114 PolarHBondContact O-N 3.38Å; I110-S114 PolarHBondContact O-OG 3.47Å; I110-W153 HydrophobicContact CG2-CE3 4.08Å; I110-W153 HydrophobicContact CG2-CZ3 3.6Å; I110-V157 HydrophobicContact CD1-CG2 3.97Å; I110-V157 HydrophobicContact CG1-CG2 4.22Å; I110-S160 WeakPolarHBondContact CG1-OG 3.49Å; I110-S160 PolarHBondContact N-OG 2.79Å
111	G	96.1	Very high	95.4	Very high	4 Å²	4	17.4 Å²	17.4	4%	0.041	9%	0.09	C	C	.	.	H	α-helix	trans	-63.5	-36.8	176	0	0	0	0	0	113	S75 L107 Y108 G115	S75-G111 PolarHBondContact OG-O 3.28Å; L107-G111 PolarHBondContact O-N 2.83Å; Y108-G111 PolarHBondContact O-N 3.27Å; G111-G115 PolarHBondContact O-N 3.36Å; G111-G115 VanDerWaalsContact O-N 3.14Å
112	F	94.4	Very high	95.2	Very high	9 Å²	9	17.5 Å²	17.5	4%	0.039	9%	0.091	C	C	.	.	H	α-helix	trans	-65.5	-54.7	175.2	175.3	-101.7	0	0	0	112.3	Y108 F109 I110 G115 I116 I198 W248	Y108-F112 WeakPolarHBondContact O-CB 3.26Å; Y108-F112 PolarHBondContact O-N 3.42Å; F109-F112 PolarHBondContact O-N 2.84Å; I110-F112 VanDerWaalsContact C-N 3.34Å; I110-F112 PolarHBondContact O-N 2.92Å; F112-G115 PolarHBondContact O-N 2.94Å; F112-I116 PolarHBondContact O-N 3.44Å; F112-I198 HydrophobicContact CE1-CG2 4.2Å; F112-I198 HydrophobicContact CZ-CG2 4.33Å; F112-W248 HydrophobicContact CD2-CD2 4.17Å; F112-W248 HydrophobicContact CD2-CE3 4.01Å; F112-W248 AromaticContact CD2-CH2 3.59Å; F112-W248 HydrophobicContact CD2-CH2 3.59Å; F112-W248 AromaticContact CD2-CZ2 3.78Å; F112-W248 HydrophobicContact CD2-CZ2 3.78Å; F112-W248 AromaticContact CD2-CZ3 3.71Å; F112-W248 HydrophobicContact CD2-CZ3 3.71Å; F112-W248 AromaticContact CE2-CD2 3.68Å; F112-W248 HydrophobicContact CE2-CD2 3.68Å; F112-W248 AromaticContact CE2-CE3 3.45Å; F112-W248 HydrophobicContact CE2-CE3 3.45Å; F112-W248 VanDerWaalsContact CE2-CE3 3.45Å; F112-W248 HydrophobicContact CE2-CG 4.37Å; F112-W248 AromaticContact CE2-CH2 3.94Å; F112-W248 HydrophobicContact CE2-CH2 3.94Å; F112-W248 HydrophobicContact CE2-CZ2 4.16Å; F112-W248 AromaticContact CE2-CZ3 3.58Å; F112-W248 HydrophobicContact CE2-CZ3 3.58Å; F112-W248 HydrophobicContact CZ-CE3 4.45Å
113	F	96.1	Very high	95	Very high	0 Å²	0	14.9 Å²	14.9	0%	0	8%	0.079	C	C	.	.	H	α-helix	trans	-69.6	-45	-176.5	-73	-58.8	0	0	0	112.7	F109 G115 I116 F117 A156 A159 K197 I198 L201	F109-F113 HydrophobicContact CB-CD2 4.23Å; F109-F113 HydrophobicContact CB-CE2 4.17Å; F109-F113 AromaticContact CD1-CE2 3.95Å; F109-F113 HydrophobicContact CD1-CE2 3.95Å; F109-F113 HydrophobicContact CG-CE2 4.39Å; F109-F113 WeakPolarHBondContact O-CD2 3.45Å; F109-F113 PolarHBondContact O-N 3.4Å; F113-G115 VanDerWaalsContact C-N 3.27Å; F113-G115 PolarHBondContact O-N 3.44Å; F113-I116 VanDerWaalsContact O-CG2 3.22Å; F113-I116 WeakPolarHBondContact O-CG2 3.17Å; F113-I116 PolarHBondContact O-N 3.22Å; F113-F117 HydrophobicContact CB-CD2 4.45Å; F113-F117 HydrophobicContact CB-CE2 4Å; F113-F117 HydrophobicContact CB-CZ 4.43Å; F113-F117 HydrophobicContact CD1-CZ 4.44Å; F113-F117 WeakPolarHBondContact O-CB 3.37Å; F113-F117 WeakPolarHBondContact O-CD2 3.31Å; F113-F117 WeakPolarHBondContact O-CG 3.4Å; F113-F117 PolarHBondContact O-N 3.39Å; F113-A156 HydrophobicContact CB-CB 4.16Å; F113-A159 HydrophobicContact CD1-CB 4.43Å; F113-A159 HydrophobicContact CD2-CB 3.84Å; F113-A159 HydrophobicContact CE2-CB 4.14Å; F113-A159 HydrophobicContact CG-CB 4.02Å; F113-K197 HydrophobicContact CZ-CD 4.46Å; F113-I198 HydrophobicContact CZ-CG1 4.18Å; F113-L201 HydrophobicContact CD1-CB 4.3Å; F113-L201 HydrophobicContact CD1-CD1 4.25Å; F113-L201 HydrophobicContact CE1-CB 4.05Å; F113-L201 HydrophobicContact CE1-CD1 3.96Å
114	S	97.1	Very high	94.8	Very high	0 Å²	0	13 Å²	13	0%	0	7%	0.068	C	C	.	.	H	α-helix	trans	-64.4	-35.9	178.1	61.4	0	0	0	0	111.3	S75 I110 I116 F117 F118 W153	S75-S114 WeakPolarHBondContact CB-OG 3.49Å; S75-S114 PolarHBondContact OG-OG 3.26Å; I110-S114 VanDerWaalsContact O-CB 3.25Å; I110-S114 WeakPolarHBondContact O-CB 3Å; I110-S114 PolarHBondContact O-N 3.38Å; I110-S114 PolarHBondContact O-OG 3.47Å; S114-I116 PolarHBondContact O-N 2.98Å; S114-F117 PolarHBondContact O-N 3.3Å; S114-F118 WeakPolarHBondContact O-CD2 3.35Å; S114-F118 PolarHBondContact O-N 2.96Å; S114-W153 WeakPolarHBondContact OG-CZ3 3.39Å
115	G	95.2	Very high	94.5	Very high	7 Å²	7	13.1 Å²	13.1	7%	0.072	7%	0.069	C	C	.	.	H	α-helix	trans	-57.1	-52.6	176.1	0	0	0	0	0	112.1	L72 S75 G111 F112 F113 F118 I119	L72-G115 WeakPolarHBondContact CD1-O 3.05Å; S75-G115 VanDerWaalsContact OG-CA 3.26Å; S75-G115 WeakPolarHBondContact OG-CA 3.14Å; S75-G115 PolarHBondContact OG-N 3.42Å; G111-G115 PolarHBondContact O-N 3.36Å; G111-G115 VanDerWaalsContact O-N 3.14Å; F112-G115 PolarHBondContact O-N 2.94Å; F113-G115 VanDerWaalsContact C-N 3.27Å; F113-G115 PolarHBondContact O-N 3.44Å; G115-F118 PolarHBondContact O-N 3.45Å; G115-I119 WeakPolarHBondContact O-CG1 3.48Å; G115-I119 PolarHBondContact O-N 3.16Å; G115-I119 VanDerWaalsContact O-N 3.1Å
116	I	94.6	Very high	94.2	Very high	0 Å²	0	15 Å²	15	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-68	-37.2	179.1	-170.1	51.9	0	0	0	112.8	F112 F113 S114 F118 I119 I120 P206 Y244	F112-I116 PolarHBondContact O-N 3.44Å; F113-I116 VanDerWaalsContact O-CG2 3.22Å; F113-I116 WeakPolarHBondContact O-CG2 3.17Å; F113-I116 PolarHBondContact O-N 3.22Å; S114-I116 PolarHBondContact O-N 2.98Å; I116-F118 PolarHBondContact O-N 3.26Å; I116-I119 HydrophobicContact CD1-CB 4.35Å; I116-I119 HydrophobicContact CD1-CG2 4.48Å; I116-I119 PolarHBondContact O-N 2.87Å; I116-I120 HydrophobicContact CG1-CD1 4.36Å; I116-I120 WeakPolarHBondContact O-CG1 3.39Å; I116-I120 PolarHBondContact O-N 3.37Å; I116-P206 HydrophobicContact CD1-CB 3.64Å; I116-P206 HydrophobicContact CD1-CG 3.46Å; I116-P206 VanDerWaalsContact CD1-CG 3.46Å; I116-P206 HydrophobicContact CG1-CB 4.09Å; I116-P206 HydrophobicContact CG1-CG 3.36Å; I116-Y244 HydrophobicContact CB-CE2 4.12Å; I116-Y244 HydrophobicContact CD1-CD1 3.74Å; I116-Y244 HydrophobicContact CD1-CD2 4.22Å; I116-Y244 HydrophobicContact CD1-CE1 3.36Å; I116-Y244 HydrophobicContact CD1-CE2 3.87Å; I116-Y244 HydrophobicContact CD1-CG 4.17Å; I116-Y244 VanDerWaalsContact CD1-CZ 3.42Å; I116-Y244 HydrophobicContact CG1-CE1 4.02Å; I116-Y244 HydrophobicContact CG1-CE2 4.32Å
117	F	96.8	Very high	93.7	Very high	24 Å²	24	17.2 Å²	17.2	11%	0.105	8%	0.083	C	C	.	.	H	α-helix	trans	-64.8	-39.7	176.3	-64.1	-25.7	0	0	0	112.3	F113 S114 I119 I120 L121 T152 V155 A156 L201 L205	F113-F117 HydrophobicContact CB-CD2 4.45Å; F113-F117 HydrophobicContact CB-CE2 4Å; F113-F117 HydrophobicContact CB-CZ 4.43Å; F113-F117 HydrophobicContact CD1-CZ 4.44Å; F113-F117 WeakPolarHBondContact O-CB 3.37Å; F113-F117 WeakPolarHBondContact O-CD2 3.31Å; F113-F117 WeakPolarHBondContact O-CG 3.4Å; F113-F117 PolarHBondContact O-N 3.39Å; S114-F117 PolarHBondContact O-N 3.3Å; F117-I119 VanDerWaalsContact C-N 3.35Å; F117-I120 HydrophobicContact CD1-CD1 4.39Å; F117-I120 WeakPolarHBondContact O-CB 3.26Å; F117-I120 PolarHBondContact O-N 2.83Å; F117-L121 WeakPolarHBondContact O-CG 3.44Å; F117-L121 PolarHBondContact O-N 2.89Å; F117-T152 HydrophobicContact CB-CG2 3.52Å; F117-T152 HydrophobicContact CD2-CG2 4.16Å; F117-T152 HydrophobicContact CG-CG2 4.31Å; F117-V155 HydrophobicContact CD2-CG1 4.49Å; F117-V155 HydrophobicContact CE2-CG1 3.81Å; F117-V155 HydrophobicContact CZ-CG1 4.3Å; F117-A156 HydrophobicContact CD2-CB 4.35Å; F117-A156 HydrophobicContact CE2-CB 4.44Å; F117-L201 HydrophobicContact CE1-CB 4.47Å; F117-L201 HydrophobicContact CE1-CD2 4.46Å; F117-L201 HydrophobicContact CZ-CD1 4.32Å; F117-L205 HydrophobicContact CE1-CD2 4.43Å
118	F	95.8	Very high	93.3	Very high	0 Å²	0	17.2 Å²	17.2	0%	0	8%	0.083	C	C	.	.	H	α-helix	trans	-68.2	-33.1	174.6	-75.9	-60.5	0	0	0	112.6	Y68 N71 L72 S114 G115 I116 L121 L122 S149 T152 W153	Y68-F118 HydrophobicContact CD1-CD1 4.21Å; Y68-F118 HydrophobicContact CD1-CE1 4.34Å; N71-F118 HydrophobicContact CB-CD1 3.78Å; N71-F118 HydrophobicContact CB-CD2 3.77Å; N71-F118 HydrophobicContact CB-CE1 3.46Å; N71-F118 VanDerWaalsContact CB-CE1 3.46Å; N71-F118 HydrophobicContact CB-CE2 3.47Å; N71-F118 VanDerWaalsContact CB-CE2 3.47Å; N71-F118 HydrophobicContact CB-CG 3.96Å; N71-F118 HydrophobicContact CB-CZ 3.32Å; L72-F118 HydrophobicContact CB-CB 4.15Å; L72-F118 HydrophobicContact CD1-CB 4.36Å; S114-F118 WeakPolarHBondContact O-CD2 3.35Å; S114-F118 PolarHBondContact O-N 2.96Å; G115-F118 PolarHBondContact O-N 3.45Å; I116-F118 PolarHBondContact O-N 3.26Å; F118-L121 HydrophobicContact CD1-CD1 3.93Å; F118-L121 HydrophobicContact CE1-CD1 4.07Å; F118-L121 PolarHBondContact O-N 3.41Å; F118-L122 WeakPolarHBondContact O-CB 3.42Å; F118-L122 VanDerWaalsContact O-CG 3.25Å; F118-L122 WeakPolarHBondContact O-CG 3.48Å; F118-L122 PolarHBondContact O-N 3.24Å; F118-S149 WeakPolarHBondContact CE1-OG 3.3Å; F118-T152 HydrophobicContact CD2-CG2 4.48Å; F118-T152 HydrophobicContact CE1-CG2 4.1Å; F118-T152 HydrophobicContact CE2-CG2 4.04Å; F118-T152 HydrophobicContact CZ-CG2 3.82Å; F118-W153 HydrophobicContact CE2-CD2 4.5Å; F118-W153 AromaticContact CE2-CE2 3.92Å; F118-W153 HydrophobicContact CE2-CZ2 4.16Å; F118-W153 AromaticContact CE2-NE1 3.87Å; F118-W153 AromaticContact CZ-NE1 3.73Å
119	I	92.9	Very high	92.8	Very high	3 Å²	3	17.7 Å²	17.7	2%	0.015	9%	0.09	C	C	.	.	H	α-helix	trans	-64.3	-41.2	170.9	-68.4	170.5	0	0	0	111.2	L72 G115 I116 F117 L122 T123 I240 M241 Y244	L72-I119 HydrophobicContact CD1-CD1 4.41Å; L72-I119 HydrophobicContact CD1-CG1 4.03Å; L72-I119 HydrophobicContact CD2-CG1 4.05Å; G115-I119 WeakPolarHBondContact O-CG1 3.48Å; G115-I119 PolarHBondContact O-N 3.16Å; G115-I119 VanDerWaalsContact O-N 3.1Å; I116-I119 HydrophobicContact CD1-CB 4.35Å; I116-I119 HydrophobicContact CD1-CG2 4.48Å; I116-I119 PolarHBondContact O-N 2.87Å; F117-I119 VanDerWaalsContact C-N 3.35Å; I119-L122 PolarHBondContact O-N 2.97Å; I119-T123 PolarHBondContact O-N 3.44Å; I119-T123 PolarHBondContact O-OG1 3.02Å; I119-I240 HydrophobicContact CD1-CG2 4.15Å; I119-I240 HydrophobicContact CG1-CG2 4.16Å; I119-M241 HydrophobicContact CG2-CE 3.41Å; I119-M241 VanDerWaalsContact CG2-CE 3.41Å; I119-M241 HydrophobicContact CG2-SD 3.68Å; I119-Y244 HydrophobicContact CD1-CD2 3.98Å; I119-Y244 HydrophobicContact CD1-CG 4.28Å
120	I	94.2	Very high	92.1	Very high	14 Å²	14	17.3 Å²	17.3	7%	0.072	9%	0.089	C	C	.	.	H	α-helix	trans	-61.6	-48.5	173.4	-73.1	166.6	0	0	0	110.5	I116 F117 L122 T123 I124 L205 P206 V209	I116-I120 HydrophobicContact CG1-CD1 4.36Å; I116-I120 WeakPolarHBondContact O-CG1 3.39Å; I116-I120 PolarHBondContact O-N 3.37Å; F117-I120 HydrophobicContact CD1-CD1 4.39Å; F117-I120 WeakPolarHBondContact O-CB 3.26Å; F117-I120 PolarHBondContact O-N 2.83Å; I120-L122 VanDerWaalsContact C-N 3.32Å; I120-L122 PolarHBondContact O-N 3.18Å; I120-T123 WeakPolarHBondContact O-CA 3.22Å; I120-T123 WeakPolarHBondContact O-CB 3.41Å; I120-T123 PolarHBondContact O-N 3.29Å; I120-I124 HydrophobicContact CG2-CD1 3.8Å; I120-I124 HydrophobicContact CG2-CG1 4.46Å; I120-I124 WeakPolarHBondContact O-CG1 3.35Å; I120-I124 PolarHBondContact O-N 2.98Å; I120-L205 HydrophobicContact CD1-CD2 3.88Å; I120-L205 HydrophobicContact CD1-CG 3.95Å; I120-P206 HydrophobicContact CD1-CB 4.25Å; I120-P206 HydrophobicContact CD1-CG 4.09Å; I120-P206 HydrophobicContact CG1-CB 4.21Å; I120-V209 HydrophobicContact CG2-CG1 4.25Å; I120-V209 HydrophobicContact CG2-CG2 4.17Å
121	L	94.6	Very high	91.5	Very high	33 Å²	33	17.9 Å²	17.9	17%	0.173	9%	0.094	C	C	.	.	H	α-helix	trans	-61.5	-38	177.8	-73.7	177.8	0	0	0	112.5	Y68 F117 F118 T123 I124 D125 T152	Y68-L121 HydrophobicContact CD1-CD1 4.4Å; Y68-L121 HydrophobicContact CD2-CB 3.96Å; Y68-L121 HydrophobicContact CE1-CD1 4.1Å; Y68-L121 HydrophobicContact CE2-CB 3.89Å; Y68-L121 HydrophobicContact CG-CB 4.32Å; F117-L121 WeakPolarHBondContact O-CG 3.44Å; F117-L121 PolarHBondContact O-N 2.89Å; F118-L121 HydrophobicContact CD1-CD1 3.93Å; F118-L121 HydrophobicContact CE1-CD1 4.07Å; F118-L121 PolarHBondContact O-N 3.41Å; L121-T123 VanDerWaalsContact C-N 3.32Å; L121-I124 PolarHBondContact O-N 3.12Å; L121-D125 VanDerWaalsContact O-CB 3.25Å; L121-D125 WeakPolarHBondContact O-CB 3.19Å; L121-D125 PolarHBondContact O-N 2.86Å; L121-T152 HydrophobicContact CD1-CG2 4.32Å; L121-T152 WeakPolarHBondContact CD1-OG1 3.47Å
122	L	91.1	Very high	90.9	Very high	2 Å²	2	21.8 Å²	21.8	1%	0.01	11%	0.111	C	C	.	.	H	α-helix	trans	-61.8	-40.9	172	-77.4	168	0	0	0	111.7	T65 Y68 L69 L72 F118 I119 I120 R126 I237	T65-L122 HydrophobicContact CG2-CD2 3.65Å; Y68-L122 HydrophobicContact CD2-CD2 4.4Å; L69-L122 HydrophobicContact CD2-CD1 3.87Å; L69-L122 HydrophobicContact CD2-CD2 4.22Å; L69-L122 HydrophobicContact CG-CD2 4.09Å; L72-L122 HydrophobicContact CD2-CD1 3.93Å; F118-L122 WeakPolarHBondContact O-CB 3.42Å; F118-L122 VanDerWaalsContact O-CG 3.25Å; F118-L122 WeakPolarHBondContact O-CG 3.48Å; F118-L122 PolarHBondContact O-N 3.24Å; I119-L122 PolarHBondContact O-N 2.97Å; I120-L122 VanDerWaalsContact C-N 3.32Å; I120-L122 PolarHBondContact O-N 3.18Å; L122-R126 WeakPolarHBondContact O-CG 3.27Å; L122-R126 PolarHBondContact O-N 3.38Å; L122-R126 VanDerWaalsContact O-N 3.1Å; L122-I237 HydrophobicContact CB-CD1 4.31Å
123	T	90.4	Very high	90.2	Very high	1 Å²	1	24 Å²	24	1%	0.006	13%	0.131	C	C	.	.	H	α-helix	trans	-64.8	-45.4	177.3	-56	0	0	0	0	111.2	I119 I120 L121 R126 Y127 V209 C213 Y214 M241	I119-T123 PolarHBondContact O-N 3.44Å; I119-T123 PolarHBondContact O-OG1 3.02Å; I120-T123 WeakPolarHBondContact O-CA 3.22Å; I120-T123 WeakPolarHBondContact O-CB 3.41Å; I120-T123 PolarHBondContact O-N 3.29Å; L121-T123 VanDerWaalsContact C-N 3.32Å; T123-R126 PolarHBondContact O-N 2.98Å; T123-Y127 WeakPolarHBondContact O-CB 3.35Å; T123-Y127 PolarHBondContact O-N 3.09Å; T123-V209 HydrophobicContact CG2-CG1 4.29Å; T123-C213 HydrophobicContact CG2-CB 3.84Å; T123-Y214 HydrophobicContact CG2-CE2 4.04Å; T123-M241 VanDerWaalsContact OG1-CE 3.3Å; T123-M241 WeakPolarHBondContact OG1-CE 3.5Å
124	I	91.4	Very high	89.3	Confident	62 Å²	62	30.1 Å²	30.1	32%	0.318	17%	0.168	S	C	.	.	H	α-helix	trans	-65.9	-44	177	-64.2	169.1	0	0	0	111.1	I120 L121 R126 Y127 L128 V209	I120-I124 HydrophobicContact CG2-CD1 3.8Å; I120-I124 HydrophobicContact CG2-CG1 4.46Å; I120-I124 WeakPolarHBondContact O-CG1 3.35Å; I120-I124 PolarHBondContact O-N 2.98Å; L121-I124 PolarHBondContact O-N 3.12Å; I124-R126 VanDerWaalsContact C-N 3.26Å; I124-R126 PolarHBondContact O-N 2.63Å; I124-Y127 WeakPolarHBondContact O-CB 3.27Å; I124-Y127 PolarHBondContact O-N 3.3Å; I124-Y127 VanDerWaalsContact O-N 3.14Å; I124-L128 HydrophobicContact CG2-CD1 4.04Å; I124-L128 HydrophobicContact CG2-CG 4.27Å; I124-L128 WeakPolarHBondContact O-CG 3.27Å; I124-L128 PolarHBondContact O-N 2.93Å; I124-V209 HydrophobicContact CD1-CG1 4.45Å; I124-V209 HydrophobicContact CG1-CG1 4.03Å
125	D	89.6	Confident	88.4	Confident	6 Å²	6	36 Å²	36	3%	0.032	19%	0.194	C	C	.	.	H	α-helix	trans	-55.3	-43.2	176	169.5	77	0	0	0	111.6	T65 Y68 L121 A129 R140	T65-D125 PolarHBondContact OG1-OD2 3.05Å; Y68-D125 HydrophobicContact CD2-CB 4.26Å; Y68-D125 HydrophobicContact CE2-CB 4.07Å; L121-D125 VanDerWaalsContact O-CB 3.25Å; L121-D125 WeakPolarHBondContact O-CB 3.19Å; L121-D125 PolarHBondContact O-N 2.86Å; D125-A129 WeakPolarHBondContact O-CB 3.34Å; D125-A129 PolarHBondContact O-N 3.49Å; D125-A129 VanDerWaalsContact O-N 3.1Å; D125-R140 VanDerWaalsContact CG-NH2 3.31Å; D125-R140 IonicContact OD1-CZ 3.76Å; D125-R140 VanDerWaalsContact OD1-CZ 3.24Å; D125-R140 IonicContact OD1-NE 2.74Å; D125-R140 PolarHBondContact OD1-NE 3.12Å; D125-R140 IonicContact OD1-NH2 3.35Å; D125-R140 PolarHBondContact OD1-NH2 3.18Å; D125-R140 IonicContact OD2-CZ 2.83Å; D125-R140 IonicContact OD2-NH2 2.65Å; D125-R140 PolarHBondContact OD2-NH2 3.12Å
126	R	86.6	Confident	87.5	Confident	47 Å²	47	36 Å²	36	18%	0.177	19%	0.193	C	C	.	.	H	α-helix	trans	-68.8	-43.2	175.7	-71.5	-57.9	101.5	-179.3	14.3	112.9	T65 L122 T123 I124 L128 A129 V130 I237	T65-R126 PolarHBondContact OG1-NH2 3.49Å; L122-R126 WeakPolarHBondContact O-CG 3.27Å; L122-R126 PolarHBondContact O-N 3.38Å; L122-R126 VanDerWaalsContact O-N 3.1Å; T123-R126 PolarHBondContact O-N 2.98Å; I124-R126 VanDerWaalsContact C-N 3.26Å; I124-R126 PolarHBondContact O-N 2.63Å; R126-L128 VanDerWaalsContact C-N 3.34Å; R126-L128 PolarHBondContact O-N 3.21Å; R126-A129 PolarHBondContact O-N 2.85Å; R126-V130 WeakPolarHBondContact O-CG2 3.33Å; R126-V130 PolarHBondContact O-N 3.41Å; R126-I237 HydrophobicContact CB-CD1 4.45Å; R126-I237 HydrophobicContact CG-CD1 3.12Å; R126-I237 HydrophobicContact CG-CG1 4.35Å
127	Y	87.3	Confident	86.6	Confident	50 Å²	50	43.2 Å²	43.2	20%	0.196	23%	0.231	C	C	.	.	H	α-helix	trans	-56.1	-51.2	177.5	173.3	-101.4	0	0	0	111	T123 I124 A129 V130 V131 H132 C213 I217	T123-Y127 WeakPolarHBondContact O-CB 3.35Å; T123-Y127 PolarHBondContact O-N 3.09Å; I124-Y127 WeakPolarHBondContact O-CB 3.27Å; I124-Y127 PolarHBondContact O-N 3.3Å; I124-Y127 VanDerWaalsContact O-N 3.14Å; Y127-A129 VanDerWaalsContact C-N 3.33Å; Y127-A129 PolarHBondContact O-N 3.27Å; Y127-V130 PolarHBondContact O-N 3.17Å; Y127-V130 VanDerWaalsContact O-N 3.15Å; Y127-V131 HydrophobicContact CD2-CB 4.31Å; Y127-V131 HydrophobicContact CD2-CG2 3.71Å; Y127-V131 HydrophobicContact CE2-CB 4.02Å; Y127-V131 HydrophobicContact CE2-CG1 4.22Å; Y127-V131 HydrophobicContact CE2-CG2 3.58Å; Y127-V131 HydrophobicContact CG-CG2 4.5Å; Y127-V131 WeakPolarHBondContact O-CB 3.49Å; Y127-V131 PolarHBondContact O-N 2.98Å; Y127-H132 AromaticContact CE1-CD2 3.7Å; Y127-H132 AromaticContact CE1-NE2 3.83Å; Y127-H132 AromaticContact CZ-NE2 3.98Å; Y127-C213 VanDerWaalsContact CD2-CA 3.45Å; Y127-C213 HydrophobicContact CD2-CB 3.85Å; Y127-C213 VanDerWaalsContact CD2-O 3.24Å; Y127-C213 WeakPolarHBondContact CD2-O 3.47Å; Y127-C213 HydrophobicContact CG-CB 4.06Å; Y127-I217 HydrophobicContact CD2-CG1 4.15Å
128	L	87	Confident	85.7	Confident	39 Å²	39	50.5 Å²	50.5	20%	0.204	26%	0.263	C	S	.	.	H	α-helix	trans	-59.9	-43.8	177.8	-67.7	175.8	0	0	0	111.5	I124 R126 V130 H132 F135	I124-L128 HydrophobicContact CG2-CD1 4.04Å; I124-L128 HydrophobicContact CG2-CG 4.27Å; I124-L128 WeakPolarHBondContact O-CG 3.27Å; I124-L128 PolarHBondContact O-N 2.93Å; R126-L128 VanDerWaalsContact C-N 3.34Å; R126-L128 PolarHBondContact O-N 3.21Å; L128-V130 VanDerWaalsContact C-N 3.25Å; L128-V130 PolarHBondContact O-N 3.18Å; L128-H132 HydrophobicContact CD2-CB 4.45Å; L128-H132 CarbonylContact O-C 3.38Å; L128-H132 WeakPolarHBondContact O-CA 3.38Å; L128-H132 PolarHBondContact O-N 2.61Å; L128-F135 HydrophobicContact CD2-CD1 4.23Å; L128-F135 HydrophobicContact CD2-CE1 4.37Å
129	A	84.8	Confident	84.7	Confident	26 Å²	26	51.8 Å²	51.8	22%	0.215	27%	0.273	C	S	.	.	H	α-helix	trans	-62.7	-29.3	178.7	0	0	0	0	0	114	D125 R126 Y127	D125-A129 WeakPolarHBondContact O-CB 3.34Å; D125-A129 PolarHBondContact O-N 3.49Å; D125-A129 VanDerWaalsContact O-N 3.1Å; R126-A129 PolarHBondContact O-N 2.85Å; Y127-A129 VanDerWaalsContact C-N 3.33Å; Y127-A129 PolarHBondContact O-N 3.27Å
130	V	81.6	Confident	84.3	Confident	13 Å²	13	55 Å²	55	8%	0.079	29%	0.285	C	S	.	.	H	α-helix	trans	-95.4	-46.1	-175.7	172.1	0	0	0	0	112.4	R126 Y127 L128 I217 T220 R230 V234	R126-V130 WeakPolarHBondContact O-CG2 3.33Å; R126-V130 PolarHBondContact O-N 3.41Å; Y127-V130 PolarHBondContact O-N 3.17Å; Y127-V130 VanDerWaalsContact O-N 3.15Å; L128-V130 VanDerWaalsContact C-N 3.25Å; L128-V130 PolarHBondContact O-N 3.18Å; V130-I217 HydrophobicContact CB-CG1 4.28Å; V130-I217 HydrophobicContact CG1-CB 4.49Å; V130-I217 HydrophobicContact CG1-CG1 4.22Å; V130-I217 HydrophobicContact CG1-CG2 4.23Å; V130-T220 HydrophobicContact CG1-CG2 4.41Å; V130-R230 HydrophobicContact CG1-CG 4.47Å; V130-R230 HydrophobicContact CG2-CG 3.81Å; V130-V234 HydrophobicContact CG2-CG2 4.37Å
131	V	84	Confident	84	Confident	36 Å²	36	57.1 Å²	57.1	22%	0.218	30%	0.299	C	S	.	.	H	α-helix	trans	-91.6	-35.5	-171.8	-177	0	0	0	0	111.4	Y127 G216 I217	Y127-V131 HydrophobicContact CD2-CB 4.31Å; Y127-V131 HydrophobicContact CD2-CG2 3.71Å; Y127-V131 HydrophobicContact CE2-CB 4.02Å; Y127-V131 HydrophobicContact CE2-CG1 4.22Å; Y127-V131 HydrophobicContact CE2-CG2 3.58Å; Y127-V131 HydrophobicContact CG-CG2 4.5Å; Y127-V131 WeakPolarHBondContact O-CB 3.49Å; Y127-V131 PolarHBondContact O-N 2.98Å; V131-G216 WeakPolarHBondContact CG2-O 3.44Å; V131-I217 HydrophobicContact CG2-CG1 4.15Å
132	H	83.5	Confident	83.8	Confident	85 Å²	85	58.5 Å²	58.5	39%	0.394	31%	0.309	S	S	.	.			trans	-122.2	51.8	-175.3	-61.5	-70.2	0	0	0	112	Y127 L128 V134 F135 A136	Y127-H132 AromaticContact CE1-CD2 3.7Å; Y127-H132 AromaticContact CE1-NE2 3.83Å; Y127-H132 AromaticContact CZ-NE2 3.98Å; L128-H132 HydrophobicContact CD2-CB 4.45Å; L128-H132 CarbonylContact O-C 3.38Å; L128-H132 WeakPolarHBondContact O-CA 3.38Å; L128-H132 PolarHBondContact O-N 2.61Å; H132-V134 VanDerWaalsContact C-N 3.28Å; H132-V134 PolarHBondContact O-N 2.83Å; H132-V134 VanDerWaalsContact O-N 3.14Å; H132-F135 HydrophobicContact CB-CB 4.22Å; H132-F135 PolarHBondContact O-N 3.48Å; H132-F135 VanDerWaalsContact O-N 3.11Å; H132-A136 WeakPolarHBondContact O-CB 3.26Å; H132-A136 PolarHBondContact O-N 2.71Å
133	A	79.3	Confident	83.7	Confident	57 Å²	57	63.4 Å²	63.4	47%	0.471	34%	0.338	S	S	.	.	H	α-helix	trans	-54.2	-36.9	-171.6	0	0	0	0	0	114.7	A136 L137	A133-A136 WeakPolarHBondContact O-CB 3.31Å; A133-A136 PolarHBondContact O-N 3.42Å; A133-L137 PolarHBondContact O-N 3.4Å
134	V	78	Confident	83.7	Confident	128 Å²	128	67.2 Å²	67.2	78%	0.776	36%	0.358	S	S	*	.	H	α-helix	trans	-69.3	-45.3	178.7	-179.6	0	0	0	0	111.5	H132 A136 L137	H132-V134 VanDerWaalsContact C-N 3.28Å; H132-V134 PolarHBondContact O-N 2.83Å; H132-V134 VanDerWaalsContact O-N 3.14Å; V134-A136 VanDerWaalsContact C-N 3.31Å; V134-A136 PolarHBondContact O-N 2.9Å; V134-L137 PolarHBondContact O-N 3.47Å
135	F	77.6	Confident	83.7	Confident	124 Å²	124	64.3 Å²	64.3	54%	0.544	34%	0.344	S	S	.	.	H	α-helix	trans	-65.5	-37.8	175.2	178.4	-101.1	0	0	0	111.6	L128 H132 L137 K138 A139	L128-F135 HydrophobicContact CD2-CD1 4.23Å; L128-F135 HydrophobicContact CD2-CE1 4.37Å; H132-F135 HydrophobicContact CB-CB 4.22Å; H132-F135 PolarHBondContact O-N 3.48Å; H132-F135 VanDerWaalsContact O-N 3.11Å; F135-L137 PolarHBondContact O-N 2.89Å; F135-K138 PolarHBondContact O-N 3.14Å; F135-A139 HydrophobicContact CD1-CB 3.95Å; F135-A139 HydrophobicContact CE1-CB 3.54Å; F135-A139 HydrophobicContact CZ-CB 3.88Å; F135-A139 WeakPolarHBondContact O-CB 3.43Å; F135-A139 PolarHBondContact O-N 3.08Å
136	A	76.9	Confident	84	Confident	7 Å²	7	67.4 Å²	67.4	6%	0.058	36%	0.363	C	S	.	.	H	α-helix	trans	-59.5	-31.3	179	0	0	0	0	0	113.4	H132 A133 V134 K138 R140	H132-A136 WeakPolarHBondContact O-CB 3.26Å; H132-A136 PolarHBondContact O-N 2.71Å; A133-A136 WeakPolarHBondContact O-CB 3.31Å; A133-A136 PolarHBondContact O-N 3.42Å; V134-A136 VanDerWaalsContact C-N 3.31Å; V134-A136 PolarHBondContact O-N 2.9Å; A136-K138 VanDerWaalsContact C-N 3.27Å; A136-K138 PolarHBondContact O-N 2.89Å; A136-R140 HydrophobicContact CB-CG 4.23Å; A136-R140 WeakPolarHBondContact O-CB 3.12Å; A136-R140 VanDerWaalsContact O-CG 3.28Å; A136-R140 WeakPolarHBondContact O-CG 3.19Å; A136-R140 PolarHBondContact O-N 2.92Å
137	L	76.2	Confident	84.4	Confident	150 Å²	150	68.8 Å²	68.8	79%	0.785	38%	0.376	S	S	*	.	H	α-helix	trans	-62	-34.6	175.4	-72.9	163.9	0	0	0	112.4	A133 V134 F135	A133-L137 PolarHBondContact O-N 3.4Å; V134-L137 PolarHBondContact O-N 3.47Å; F135-L137 PolarHBondContact O-N 2.89Å
138	K	76.3	Confident	84.8	Confident	177 Å²	177	68.5 Å²	68.5	77%	0.77	38%	0.38	S	S	*	.	H	α-helix	trans	-88.5	-35.5	179.1	-169.4	176.4	179.9	179.6	0	112.6	F135 A136	F135-K138 PolarHBondContact O-N 3.14Å; A136-K138 VanDerWaalsContact C-N 3.27Å; A136-K138 PolarHBondContact O-N 2.89Å
139	A	76.2	Confident	85.3	Confident	27 Å²	27	66.8 Å²	66.8	22%	0.223	37%	0.371	C	S	.	.	H	α-helix	trans	-89.3	-19	-172.6	0	0	0	0	0	114.8	F135 T141 L144	F135-A139 HydrophobicContact CD1-CB 3.95Å; F135-A139 HydrophobicContact CE1-CB 3.54Å; F135-A139 HydrophobicContact CZ-CB 3.88Å; F135-A139 WeakPolarHBondContact O-CB 3.43Å; F135-A139 PolarHBondContact O-N 3.08Å; A139-T141 PolarHBondContact O-N 2.84Å; A139-L144 WeakPolarHBondContact O-CD1 2.87Å
140	R	84.6	Confident	85.9	Confident	72 Å²	72	69.7 Å²	69.7	27%	0.272	39%	0.386	S	S	.	.			trans	-99.4	49.8	-176.6	-58.9	176.1	69.8	-138.1	-3	112.3	T64 T65 D125 A136	T64-R140 VanDerWaalsContact OG1-C 3.26Å; T64-R140 PolarHBondContact OG1-O 3.39Å; T65-R140 PolarHBondContact OG1-NH2 2.84Å; D125-R140 VanDerWaalsContact CG-NH2 3.31Å; D125-R140 IonicContact OD1-CZ 3.76Å; D125-R140 VanDerWaalsContact OD1-CZ 3.24Å; D125-R140 IonicContact OD1-NE 2.74Å; D125-R140 PolarHBondContact OD1-NE 3.12Å; D125-R140 IonicContact OD1-NH2 3.35Å; D125-R140 PolarHBondContact OD1-NH2 3.18Å; D125-R140 IonicContact OD2-CZ 2.83Å; D125-R140 IonicContact OD2-NH2 2.65Å; D125-R140 PolarHBondContact OD2-NH2 3.12Å; A136-R140 HydrophobicContact CB-CG 4.23Å; A136-R140 WeakPolarHBondContact O-CB 3.12Å; A136-R140 VanDerWaalsContact O-CG 3.28Å; A136-R140 WeakPolarHBondContact O-CG 3.19Å; A136-R140 PolarHBondContact O-N 2.92Å
141	T	87.6	Confident	86.7	Confident	57 Å²	57	73.7 Å²	73.7	35%	0.35	41%	0.406	S	S	.	.			trans	-83.3	154.1	172.1	64.4	0	0	0	0	110.3	T64 A139 T143 L144 G145	T64-T141 PolarHBondContact OG1-O 3.42Å; T64-T141 VanDerWaalsContact OG1-O 3.11Å; A139-T141 PolarHBondContact O-N 2.84Å; T141-T143 VanDerWaalsContact C-N 3.29Å; T141-T143 PolarHBondContact O-N 2.93Å; T141-L144 PolarHBondContact O-N 3.25Å; T141-L144 WeakPolarHBondContact OG1-CB 3.27Å; T141-L144 VanDerWaalsContact OG1-CG 3.29Å; T141-L144 WeakPolarHBondContact OG1-CG 3.3Å; T141-L144 PolarHBondContact OG1-N 3.29Å; T141-G145 PolarHBondContact O-N 3.18Å; T141-G145 VanDerWaalsContact O-N 3.08Å
142	V	88.8	Confident	87.4	Confident	63 Å²	63	72.8 Å²	72.8	38%	0.382	40%	0.401	S	S	.	.	H	α-helix	trans	-60.4	-42.4	175.5	165.6	0	0	0	0	110.4	I67 L144 G145 V146	I67-V142 HydrophobicContact CD1-CB 4.13Å; I67-V142 HydrophobicContact CD1-CG1 3.73Å; I67-V142 HydrophobicContact CD1-CG2 4.34Å; I67-V142 WeakPolarHBondContact CD1-O 3.41Å; V142-L144 PolarHBondContact O-N 3.1Å; V142-G145 WeakPolarHBondContact O-CA 2.94Å; V142-G145 PolarHBondContact O-N 3.09Å; V142-G145 VanDerWaalsContact O-N 3.12Å; V142-V146 WeakPolarHBondContact O-CG2 3.48Å; V142-V146 PolarHBondContact O-N 3.14Å
143	T	90.1	Very high	88.1	Confident	104 Å²	104	71 Å²	71	64%	0.638	39%	0.39	S	S	*	.	H	α-helix	trans	-58.5	-48.1	178.6	-46.5	0	0	0	0	112.2	T141 G145 V146 V147	T141-T143 VanDerWaalsContact C-N 3.29Å; T141-T143 PolarHBondContact O-N 2.93Å; T143-G145 VanDerWaalsContact C-N 3.29Å; T143-G145 PolarHBondContact O-N 3.43Å; T143-V146 PolarHBondContact O-N 2.94Å; T143-V147 WeakPolarHBondContact O-CG2 3.38Å; T143-V147 PolarHBondContact O-N 2.84Å
144	L	90.3	Very high	88.9	Confident	81 Å²	81	71.7 Å²	71.7	42%	0.424	39%	0.389	S	S	.	.	H	α-helix	trans	-63.1	-38.8	176.4	-72	174.7	0	0	0	111.4	A139 T141 V142 V146 V147 T148	A139-L144 WeakPolarHBondContact O-CD1 2.87Å; T141-L144 PolarHBondContact O-N 3.25Å; T141-L144 WeakPolarHBondContact OG1-CB 3.27Å; T141-L144 VanDerWaalsContact OG1-CG 3.29Å; T141-L144 WeakPolarHBondContact OG1-CG 3.3Å; T141-L144 PolarHBondContact OG1-N 3.29Å; V142-L144 PolarHBondContact O-N 3.1Å; L144-V146 VanDerWaalsContact C-N 3.33Å; L144-V146 PolarHBondContact O-N 3.47Å; L144-V147 PolarHBondContact O-N 3.4Å; L144-T148 WeakPolarHBondContact O-CG2 3.38Å; L144-T148 PolarHBondContact O-N 3.14Å; L144-T148 PolarHBondContact O-OG1 2.65Å
145	G	92.3	Very high	89.9	Confident	1 Å²	1	68.9 Å²	68.9	1%	0.01	37%	0.372	C	S	.	.	H	α-helix	trans	-60.1	-38.2	173.9	0	0	0	0	0	114.2	T141 V142 T143 T148 S149	T141-G145 PolarHBondContact O-N 3.18Å; T141-G145 VanDerWaalsContact O-N 3.08Å; V142-G145 WeakPolarHBondContact O-CA 2.94Å; V142-G145 PolarHBondContact O-N 3.09Å; V142-G145 VanDerWaalsContact O-N 3.12Å; T143-G145 VanDerWaalsContact C-N 3.29Å; T143-G145 PolarHBondContact O-N 3.43Å; G145-T148 WeakPolarHBondContact CA-OG1 3.39Å; G145-T148 PolarHBondContact O-OG1 3.33Å; G145-S149 WeakPolarHBondContact O-CB 3.38Å; G145-S149 PolarHBondContact O-N 3.49Å; G145-S149 VanDerWaalsContact O-N 3.09Å; G145-S149 PolarHBondContact O-OG 3.19Å; G145-S149 VanDerWaalsContact O-OG 3.08Å
146	V	94.6	Very high	90.8	Very high	72 Å²	72	63 Å²	63	44%	0.436	35%	0.346	S	S	.	.	H	α-helix	trans	-68.7	-46.1	175.4	174.7	0	0	0	0	110.6	I67 V142 T143 L144 T148 S149 V150	I67-V146 HydrophobicContact CD1-CG2 4.13Å; V142-V146 WeakPolarHBondContact O-CG2 3.48Å; V142-V146 PolarHBondContact O-N 3.14Å; T143-V146 PolarHBondContact O-N 2.94Å; L144-V146 VanDerWaalsContact C-N 3.33Å; L144-V146 PolarHBondContact O-N 3.47Å; V146-T148 PolarHBondContact O-N 3.05Å; V146-S149 WeakPolarHBondContact O-CB 3.31Å; V146-S149 PolarHBondContact O-N 3.46Å; V146-V150 WeakPolarHBondContact O-CG2 3.4Å; V146-V150 PolarHBondContact O-N 3.44Å
147	V	96	Very high	91.8	Very high	76 Å²	76	65.5 Å²	65.5	46%	0.461	36%	0.36	S	S	.	.	H	α-helix	trans	-61	-46.2	179.3	173.6	0	0	0	0	111.1	T143 L144 S149 V150 I151	T143-V147 WeakPolarHBondContact O-CG2 3.38Å; T143-V147 PolarHBondContact O-N 2.84Å; L144-V147 PolarHBondContact O-N 3.4Å; V147-S149 VanDerWaalsContact C-N 3.33Å; V147-S149 PolarHBondContact O-N 2.92Å; V147-V150 PolarHBondContact O-N 3.37Å; V147-I151 HydrophobicContact CG1-CD1 3.95Å; V147-I151 WeakPolarHBondContact O-CG1 3.41Å; V147-I151 PolarHBondContact O-N 2.85Å
148	T	95.8	Very high	92.7	Very high	43 Å²	43	64.8 Å²	64.8	26%	0.264	35%	0.351	S	S	.	.	H	α-helix	trans	-64	-37.4	177.3	52.8	0	0	0	0	112.2	Y68 L144 G145 V146 I151 T152	Y68-T148 WeakPolarHBondContact CE1-OG1 3.31Å; Y68-T148 PolarHBondContact OH-OG1 2.79Å; L144-T148 WeakPolarHBondContact O-CG2 3.38Å; L144-T148 PolarHBondContact O-N 3.14Å; L144-T148 PolarHBondContact O-OG1 2.65Å; G145-T148 WeakPolarHBondContact CA-OG1 3.39Å; G145-T148 PolarHBondContact O-OG1 3.33Å; V146-T148 PolarHBondContact O-N 3.05Å; T148-I151 PolarHBondContact O-N 3.5Å; T148-T152 WeakPolarHBondContact O-CB 3.47Å; T148-T152 PolarHBondContact O-N 3.36Å; T148-T152 PolarHBondContact O-OG1 3.49Å
149	S	97	Very high	93.6	Very high	4 Å²	4	57 Å²	57	3%	0.028	32%	0.32	C	S	.	.	H	α-helix	trans	-61.9	-46.3	172.7	-74	0	0	0	0	112.3	N71 F118 G145 V146 V147 I151 T152 W153	N71-S149 PolarHBondContact ND2-OG 3Å; F118-S149 WeakPolarHBondContact CE1-OG 3.3Å; G145-S149 WeakPolarHBondContact O-CB 3.38Å; G145-S149 PolarHBondContact O-N 3.49Å; G145-S149 VanDerWaalsContact O-N 3.09Å; G145-S149 PolarHBondContact O-OG 3.19Å; G145-S149 VanDerWaalsContact O-OG 3.08Å; V146-S149 WeakPolarHBondContact O-CB 3.31Å; V146-S149 PolarHBondContact O-N 3.46Å; V147-S149 VanDerWaalsContact C-N 3.33Å; V147-S149 PolarHBondContact O-N 2.92Å; S149-I151 PolarHBondContact O-N 2.89Å; S149-T152 WeakPolarHBondContact O-CB 3.34Å; S149-T152 PolarHBondContact O-N 2.99Å; S149-T152 VanDerWaalsContact O-N 3.15Å; S149-W153 PolarHBondContact O-N 3.46Å
150	V	97.8	Very high	94.5	Very high	87 Å²	87	55.8 Å²	55.8	53%	0.527	31%	0.309	S	S	.	.	H	α-helix	trans	-60.2	-46	178.1	171.4	0	0	0	0	110.9	V146 V147 T152 W153 V154	V146-V150 WeakPolarHBondContact O-CG2 3.4Å; V146-V150 PolarHBondContact O-N 3.44Å; V147-V150 PolarHBondContact O-N 3.37Å; V150-T152 VanDerWaalsContact C-N 3.27Å; V150-T152 PolarHBondContact O-N 3.42Å; V150-W153 PolarHBondContact O-N 3.45Å; V150-V154 WeakPolarHBondContact O-CG2 3.29Å; V150-V154 PolarHBondContact O-N 2.95Å
151	I	97.9	Very high	94.9	Very high	97 Å²	97	55.5 Å²	55.5	50%	0.497	31%	0.313	S	S	.	.	H	α-helix	trans	-59.5	-42.3	176.2	-66.2	166.5	0	0	0	110.4	V147 T148 S149 W153 V154 V155	V147-I151 HydrophobicContact CG1-CD1 3.95Å; V147-I151 WeakPolarHBondContact O-CG1 3.41Å; V147-I151 PolarHBondContact O-N 2.85Å; T148-I151 PolarHBondContact O-N 3.5Å; S149-I151 PolarHBondContact O-N 2.89Å; I151-W153 PolarHBondContact O-N 3.33Å; I151-V154 PolarHBondContact O-N 3.48Å; I151-V155 HydrophobicContact CG2-CG2 4.3Å; I151-V155 VanDerWaalsContact O-CG2 3.3Å; I151-V155 WeakPolarHBondContact O-CG2 3.4Å; I151-V155 PolarHBondContact O-N 2.96Å
152	T	97.9	Very high	95.1	Very high	17 Å²	17	53.9 Å²	53.9	10%	0.104	30%	0.304	C	S	.	.	H	α-helix	trans	-65	-39.5	-179.4	-62.4	0	0	0	0	112.1	F117 F118 L121 T148 S149 V150 V155 A156	F117-T152 HydrophobicContact CB-CG2 3.52Å; F117-T152 HydrophobicContact CD2-CG2 4.16Å; F117-T152 HydrophobicContact CG-CG2 4.31Å; F118-T152 HydrophobicContact CD2-CG2 4.48Å; F118-T152 HydrophobicContact CE1-CG2 4.1Å; F118-T152 HydrophobicContact CE2-CG2 4.04Å; F118-T152 HydrophobicContact CZ-CG2 3.82Å; L121-T152 HydrophobicContact CD1-CG2 4.32Å; L121-T152 WeakPolarHBondContact CD1-OG1 3.47Å; T148-T152 WeakPolarHBondContact O-CB 3.47Å; T148-T152 PolarHBondContact O-N 3.36Å; T148-T152 PolarHBondContact O-OG1 3.49Å; S149-T152 WeakPolarHBondContact O-CB 3.34Å; S149-T152 PolarHBondContact O-N 2.99Å; S149-T152 VanDerWaalsContact O-N 3.15Å; V150-T152 VanDerWaalsContact C-N 3.27Å; V150-T152 PolarHBondContact O-N 3.42Å; T152-V155 PolarHBondContact O-N 2.84Å; T152-A156 WeakPolarHBondContact O-CB 3.35Å; T152-A156 PolarHBondContact O-N 3.06Å
153	W	98.1	Very high	95.1	Very high	46 Å²	46	51 Å²	51	17%	0.174	29%	0.286	C	S	.	.	H	α-helix	trans	-61.4	-46	172.4	-80.9	112	0	0	0	112	N71 I74 F78 I110 S114 F118 S149 V150 I151 V155 A156 V157	N71-W153 PolarHBondContact OD1-NE1 3.42Å; I74-W153 HydrophobicContact CB-CZ2 4.27Å; I74-W153 HydrophobicContact CG2-CH2 4Å; I74-W153 HydrophobicContact CG2-CZ2 3.79Å; F78-W153 AromaticContact CD2-CH2 3.56Å; F78-W153 HydrophobicContact CD2-CH2 3.56Å; F78-W153 AromaticContact CD2-CZ3 3.55Å; F78-W153 HydrophobicContact CD2-CZ3 3.55Å; F78-W153 HydrophobicContact CE2-CE3 4.32Å; F78-W153 AromaticContact CE2-CH2 3.46Å; F78-W153 HydrophobicContact CE2-CH2 3.46Å; F78-W153 VanDerWaalsContact CE2-CH2 3.46Å; F78-W153 HydrophobicContact CE2-CZ2 4.41Å; F78-W153 AromaticContact CE2-CZ3 3.41Å; F78-W153 HydrophobicContact CE2-CZ3 3.41Å; F78-W153 VanDerWaalsContact CE2-CZ3 3.41Å; F78-W153 HydrophobicContact CZ-CH2 4.49Å; I110-W153 HydrophobicContact CG2-CE3 4.08Å; I110-W153 HydrophobicContact CG2-CZ3 3.6Å; S114-W153 WeakPolarHBondContact OG-CZ3 3.39Å; F118-W153 HydrophobicContact CE2-CD2 4.5Å; F118-W153 AromaticContact CE2-CE2 3.92Å; F118-W153 HydrophobicContact CE2-CZ2 4.16Å; F118-W153 AromaticContact CE2-NE1 3.87Å; F118-W153 AromaticContact CZ-NE1 3.73Å; S149-W153 PolarHBondContact O-N 3.46Å; V150-W153 PolarHBondContact O-N 3.45Å; I151-W153 PolarHBondContact O-N 3.33Å; W153-V155 VanDerWaalsContact C-N 3.34Å; W153-V155 PolarHBondContact O-N 3.27Å; W153-A156 PolarHBondContact O-N 3.46Å; W153-V157 WeakPolarHBondContact O-CG2 3.18Å; W153-V157 PolarHBondContact O-N 3.11Å
154	V	98.1	Very high	95.2	Very high	72 Å²	72	47.9 Å²	47.9	44%	0.436	27%	0.265	S	S	.	.	H	α-helix	trans	-58.7	-47.7	176.6	172.3	0	0	0	0	110.5	V150 I151 A156 V157 F158	V150-V154 WeakPolarHBondContact O-CG2 3.29Å; V150-V154 PolarHBondContact O-N 2.95Å; I151-V154 PolarHBondContact O-N 3.48Å; V154-A156 PolarHBondContact O-N 3.48Å; V154-V157 PolarHBondContact O-N 2.85Å; V154-F158 HydrophobicContact CG1-CD2 3.63Å; V154-F158 HydrophobicContact CG1-CE2 3.51Å; V154-F158 WeakPolarHBondContact O-CD2 3.24Å; V154-F158 PolarHBondContact O-N 2.77Å
155	V	97.7	Very high	95.2	Very high	69 Å²	69	49 Å²	49	42%	0.418	27%	0.271	S	S	.	.	H	α-helix	trans	-61.2	-41.7	177.2	174.4	0	0	0	0	111.7	F117 I151 T152 W153 V157 F158 A159	F117-V155 HydrophobicContact CD2-CG1 4.49Å; F117-V155 HydrophobicContact CE2-CG1 3.81Å; F117-V155 HydrophobicContact CZ-CG1 4.3Å; I151-V155 HydrophobicContact CG2-CG2 4.3Å; I151-V155 VanDerWaalsContact O-CG2 3.3Å; I151-V155 WeakPolarHBondContact O-CG2 3.4Å; I151-V155 PolarHBondContact O-N 2.96Å; T152-V155 PolarHBondContact O-N 2.84Å; W153-V155 VanDerWaalsContact C-N 3.34Å; W153-V155 PolarHBondContact O-N 3.27Å; V155-V157 PolarHBondContact O-N 3.42Å; V155-F158 PolarHBondContact O-N 2.93Å; V155-A159 WeakPolarHBondContact O-CB 3.46Å; V155-A159 PolarHBondContact O-N 2.92Å
156	A	97.4	Very high	95.2	Very high	0 Å²	0	50 Å²	50	0%	0	28%	0.275	C	S	.	.	H	α-helix	trans	-63.9	-39.6	177.3	0	0	0	0	0	112.4	F113 F117 T152 W153 V154 A159 S160	F113-A156 HydrophobicContact CB-CB 4.16Å; F117-A156 HydrophobicContact CD2-CB 4.35Å; F117-A156 HydrophobicContact CE2-CB 4.44Å; T152-A156 WeakPolarHBondContact O-CB 3.35Å; T152-A156 PolarHBondContact O-N 3.06Å; W153-A156 PolarHBondContact O-N 3.46Å; V154-A156 PolarHBondContact O-N 3.48Å; A156-A159 PolarHBondContact O-N 3.3Å; A156-S160 WeakPolarHBondContact O-CB 3.22Å; A156-S160 PolarHBondContact O-N 3.48Å; A156-S160 VanDerWaalsContact O-N 3.12Å; A156-S160 PolarHBondContact O-OG 2.83Å
157	V	97.1	Very high	95	Very high	60 Å²	60	46.8 Å²	46.8	36%	0.364	26%	0.255	S	S	.	.	H	α-helix	trans	-62.7	-50.2	173.8	172	0	0	0	0	110.3	I110 W153 V154 V155 A159 S160 L161	I110-V157 HydrophobicContact CD1-CG2 3.97Å; I110-V157 HydrophobicContact CG1-CG2 4.22Å; W153-V157 WeakPolarHBondContact O-CG2 3.18Å; W153-V157 PolarHBondContact O-N 3.11Å; V154-V157 PolarHBondContact O-N 2.85Å; V155-V157 PolarHBondContact O-N 3.42Å; V157-A159 VanDerWaalsContact C-N 3.33Å; V157-A159 PolarHBondContact O-N 3.38Å; V157-S160 WeakPolarHBondContact O-CA 3.28Å; V157-S160 WeakPolarHBondContact O-CB 3.37Å; V157-S160 PolarHBondContact O-N 3.45Å; V157-L161 WeakPolarHBondContact O-CG 3.44Å; V157-L161 PolarHBondContact O-N 3.48Å; V157-L161 VanDerWaalsContact O-N 3.08Å
158	F	96.3	Very high	94.8	Very high	136 Å²	136	50.1 Å²	50.1	60%	0.596	26%	0.26	S	S	*	.	H	α-helix	trans	-58.9	-41.8	177.6	-83.7	-70.5	0	0	0	112.8	V154 V155 S160 L161	V154-F158 HydrophobicContact CG1-CD2 3.63Å; V154-F158 HydrophobicContact CG1-CE2 3.51Å; V154-F158 WeakPolarHBondContact O-CD2 3.24Å; V154-F158 PolarHBondContact O-N 2.77Å; V155-F158 PolarHBondContact O-N 2.93Å; F158-S160 PolarHBondContact O-N 2.87Å; F158-L161 HydrophobicContact CD1-CD1 3.62Å; F158-L161 HydrophobicContact CE1-CD1 4.08Å; F158-L161 HydrophobicContact CG-CD1 4.44Å; F158-L161 PolarHBondContact O-N 3.31Å
159	A	94.8	Very high	94.6	Very high	14 Å²	14	49.3 Å²	49.3	12%	0.116	26%	0.255	C	S	.	.	H	α-helix	trans	-63	-27.3	175.8	0	0	0	0	0	112.9	F113 V155 A156 V157 K197 L201	F113-A159 HydrophobicContact CD1-CB 4.43Å; F113-A159 HydrophobicContact CD2-CB 3.84Å; F113-A159 HydrophobicContact CE2-CB 4.14Å; F113-A159 HydrophobicContact CG-CB 4.02Å; V155-A159 WeakPolarHBondContact O-CB 3.46Å; V155-A159 PolarHBondContact O-N 2.92Å; A156-A159 PolarHBondContact O-N 3.3Å; V157-A159 VanDerWaalsContact C-N 3.33Å; V157-A159 PolarHBondContact O-N 3.38Å; A159-K197 PolarHBondContact O-NZ 3.47Å; A159-L201 HydrophobicContact CB-CD1 4.42Å
160	S	94.9	Very high	94.1	Very high	0 Å²	0	52.9 Å²	52.9	0%	0	27%	0.272	C	S	.	.	H	α-helix	trans	-84.8	-25.5	-179.3	-55.9	0	0	0	0	113.3	F109 I110 A156 V157 F158 G163 I164	F109-S160 VanDerWaalsContact C-OG 3.24Å; F109-S160 WeakPolarHBondContact CB-OG 3.29Å; I110-S160 WeakPolarHBondContact CG1-OG 3.49Å; I110-S160 PolarHBondContact N-OG 2.79Å; A156-S160 WeakPolarHBondContact O-CB 3.22Å; A156-S160 PolarHBondContact O-N 3.48Å; A156-S160 VanDerWaalsContact O-N 3.12Å; A156-S160 PolarHBondContact O-OG 2.83Å; V157-S160 WeakPolarHBondContact O-CA 3.28Å; V157-S160 WeakPolarHBondContact O-CB 3.37Å; V157-S160 PolarHBondContact O-N 3.45Å; F158-S160 PolarHBondContact O-N 2.87Å; S160-G163 WeakPolarHBondContact O-CA 3.14Å; S160-G163 PolarHBondContact O-N 3.46Å; S160-I164 PolarHBondContact O-N 3.46Å; S160-I164 VanDerWaalsContact O-N 3.17Å
161	L	93.5	Very high	93.6	Very high	66 Å²	66	54.9 Å²	54.9	35%	0.346	27%	0.273	S	S	.	.	H	α-helix	trans	-50.9	-47	-175.1	-72.4	176.3	0	0	0	114.6	V157 F158 G163 I164 I165	V157-L161 WeakPolarHBondContact O-CG 3.44Å; V157-L161 PolarHBondContact O-N 3.48Å; V157-L161 VanDerWaalsContact O-N 3.08Å; F158-L161 HydrophobicContact CD1-CD1 3.62Å; F158-L161 HydrophobicContact CE1-CD1 4.08Å; F158-L161 HydrophobicContact CG-CD1 4.44Å; F158-L161 PolarHBondContact O-N 3.31Å; L161-G163 VanDerWaalsContact C-N 3.26Å; L161-G163 PolarHBondContact O-N 2.88Å; L161-I164 PolarHBondContact O-N 3.06Å; L161-I164 VanDerWaalsContact O-N 3.09Å; L161-I165 VanDerWaalsContact O-CG1 3.32Å; L161-I165 WeakPolarHBondContact O-CG1 3.41Å; L161-I165 PolarHBondContact O-N 2.88Å
162	P	90.6	Very high	92.8	Very high	24 Å²	24	54.4 Å²	54.4	16%	0.156	27%	0.269	C	S	.	.	H	α-helix	trans	-59.8	-39.1	178.6	-23.6	34.5	0	0	0	112.1	I164 I165 F166 F193	P162-I164 VanDerWaalsContact C-N 3.3Å; P162-I164 PolarHBondContact O-N 3.23Å; P162-I165 PolarHBondContact O-N 3.45Å; P162-F166 HydrophobicContact CB-CD2 4.41Å; P162-F166 HydrophobicContact CB-CE2 4.28Å; P162-F166 WeakPolarHBondContact O-CD2 3.25Å; P162-F166 PolarHBondContact O-N 3.33Å; P162-F166 VanDerWaalsContact O-N 3.12Å; P162-F193 HydrophobicContact CG-CE1 4.27Å
163	G	88.3	Confident	92	Very high	1 Å²	1	56.9 Å²	56.9	1%	0.01	30%	0.298	C	S	.	.	H	α-helix	trans	-63.7	-36.7	177	0	0	0	0	0	112.5	S160 L161 T167	S160-G163 WeakPolarHBondContact O-CA 3.14Å; S160-G163 PolarHBondContact O-N 3.46Å; L161-G163 VanDerWaalsContact C-N 3.26Å; L161-G163 PolarHBondContact O-N 2.88Å; G163-T167 WeakPolarHBondContact O-CB 3.25Å; G163-T167 PolarHBondContact O-N 3.38Å; G163-T167 PolarHBondContact O-OG1 3.04Å
164	I	91.9	Very high	91.1	Very high	40 Å²	40	62 Å²	62	21%	0.205	33%	0.328	C	S	.	.	H	α-helix	trans	-70.4	-43.6	178.1	-59.8	167.7	0	0	0	110.9	Q102 G106 S160 L161 P162 T167	Q102-I164 HydrophobicContact CB-CG2 4.2Å; G106-I164 VanDerWaalsContact CA-CG1 3.48Å; S160-I164 PolarHBondContact O-N 3.46Å; S160-I164 VanDerWaalsContact O-N 3.17Å; L161-I164 PolarHBondContact O-N 3.06Å; L161-I164 VanDerWaalsContact O-N 3.09Å; P162-I164 VanDerWaalsContact C-N 3.3Å; P162-I164 PolarHBondContact O-N 3.23Å; I164-T167 PolarHBondContact O-N 3.24Å
165	I	92.1	Very high	90.5	Very high	104 Å²	104	62.4 Å²	62.4	53%	0.533	33%	0.325	S	S	.	.	H	α-helix	trans	-66.6	-42.3	-175.9	-67	164.9	0	0	0	111.5	L161 P162	L161-I165 VanDerWaalsContact O-CG1 3.32Å; L161-I165 WeakPolarHBondContact O-CG1 3.41Å; L161-I165 PolarHBondContact O-N 2.88Å; P162-I165 PolarHBondContact O-N 3.45Å
166	F	91.2	Very high	90	Very high	23 Å²	23	64.5 Å²	64.5	10%	0.101	33%	0.326	C	S	.	.	H	α-helix	trans	-82.8	-16.1	-178.2	-64.5	-57.8	0	0	0	113.4	P162 H181 F182 P183 W190	P162-F166 HydrophobicContact CB-CD2 4.41Å; P162-F166 HydrophobicContact CB-CE2 4.28Å; P162-F166 WeakPolarHBondContact O-CD2 3.25Å; P162-F166 PolarHBondContact O-N 3.33Å; P162-F166 VanDerWaalsContact O-N 3.12Å; F166-H181 PolarHBondContact O-N 3.38Å; F166-F182 HydrophobicContact CB-CD1 3.89Å; F166-F182 HydrophobicContact CB-CE1 3.84Å; F166-F182 AromaticContact CD1-CD1 4Å; F166-F182 HydrophobicContact CD1-CD1 4Å; F166-F182 AromaticContact CD2-CD1 3.87Å; F166-F182 HydrophobicContact CD2-CD1 3.87Å; F166-F182 AromaticContact CD2-CE1 3.81Å; F166-F182 HydrophobicContact CD2-CE1 3.81Å; F166-F182 HydrophobicContact CE2-CD1 4.48Å; F166-F182 AromaticContact CG-CD1 3.63Å; F166-F182 HydrophobicContact CG-CD1 3.63Å; F166-F182 AromaticContact CG-CE1 3.85Å; F166-F182 HydrophobicContact CG-CE1 3.85Å; F166-P183 HydrophobicContact CE1-CG 4.02Å; F166-W190 HydrophobicContact CD2-CE3 4.39Å; F166-W190 HydrophobicContact CE1-CD2 4.3Å; F166-W190 AromaticContact CE2-CD2 3.73Å; F166-W190 HydrophobicContact CE2-CD2 3.73Å; F166-W190 AromaticContact CE2-CE3 3.26Å; F166-W190 HydrophobicContact CE2-CE3 3.26Å; F166-W190 HydrophobicContact CE2-CG 4.39Å; F166-W190 HydrophobicContact CE2-CH2 4.2Å; F166-W190 AromaticContact CE2-CZ3 3.53Å; F166-W190 HydrophobicContact CE2-CZ3 3.53Å; F166-W190 AromaticContact CZ-CD2 3.4Å; F166-W190 HydrophobicContact CZ-CD2 3.4Å; F166-W190 VanDerWaalsContact CZ-CD2 3.4Å; F166-W190 AromaticContact CZ-CE2 3.66Å; F166-W190 AromaticContact CZ-CE3 3.41Å; F166-W190 HydrophobicContact CZ-CE3 3.41Å; F166-W190 VanDerWaalsContact CZ-CE3 3.41Å; F166-W190 HydrophobicContact CZ-CG 4.01Å; F166-W190 AromaticContact CZ-CH2 3.89Å; F166-W190 HydrophobicContact CZ-CH2 3.89Å; F166-W190 AromaticContact CZ-CZ2 3.9Å; F166-W190 HydrophobicContact CZ-CZ2 3.9Å; F166-W190 AromaticContact CZ-CZ3 3.66Å; F166-W190 HydrophobicContact CZ-CZ3 3.66Å
167	T	91.1	Very high	89.6	Confident	3 Å²	3	65.3 Å²	65.3	2%	0.018	33%	0.331	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-84.3	128.1	179.2	-59.2	0	0	0	0	111.2	C101 Q102 T105 G163 I164 S179 S180	C101-T167 WeakPolarHBondContact SG-CG2 3.34Å; Q102-T167 WeakPolarHBondContact CG-O 3.37Å; Q102-T167 PolarHBondContact NE2-O 3.18Å; T105-T167 HydrophobicContact CG2-CG2 4.08Å; T105-T167 WeakPolarHBondContact OG1-CG2 3.16Å; G163-T167 WeakPolarHBondContact O-CB 3.25Å; G163-T167 PolarHBondContact O-N 3.38Å; G163-T167 PolarHBondContact O-OG1 3.04Å; I164-T167 PolarHBondContact O-N 3.24Å; T167-S179 WeakPolarHBondContact CA-O 3.28Å; T167-S180 PolarHBondContact OG1-OG 3.47Å
168	R	91.2	Very high	89.4	Confident	147 Å²	147	63 Å²	63	56%	0.555	32%	0.317	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-139.9	156.1	178.5	-62.7	-170.7	179.7	-160	-0.7	110.7	N98 S179	N98-R168 VanDerWaalsContact OD1-CA 3.28Å; N98-R168 WeakPolarHBondContact OD1-CA 3.28Å; R168-S179 PolarHBondContact N-O 2.89Å; R168-S179 PolarHBondContact O-N 2.96Å; R168-S179 VanDerWaalsContact O-N 3.15Å
169	S	91.1	Very high	89	Confident	25 Å²	25	58.1 Å²	58.1	18%	0.175	30%	0.3	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-94.1	125.3	167.2	-175.6	0	0	0	0	110.1	N98 T177	N98-S169 PolarHBondContact OD1-N 3.12Å; S169-T177 WeakPolarHBondContact CA-O 3.41Å; S169-T177 PolarHBondContact OG-O 3.45Å; S169-T177 VanDerWaalsContact OG-O 3.09Å
170	Q	87.9	Confident	88.6	Confident	79 Å²	79	60 Å²	60	37%	0.369	31%	0.313	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-140.5	160.6	176.3	61.8	171.2	29.5	0	0	111.3	E172 T177 H181	Q170-E172 HydrophobicContact CG-CG 4.16Å; Q170-E172 PolarHBondContact NE2-OE1 3.49Å; Q170-T177 PolarHBondContact N-O 3Å; Q170-T177 PolarHBondContact O-N 3.28Å; Q170-T177 PolarHBondContact O-OG1 3.44Å; Q170-H181 WeakPolarHBondContact CG-NE2 3.09Å; Q170-H181 PolarHBondContact NE2-CE1 3.03Å; Q170-H181 PolarHBondContact NE2-NE2 2.94Å
171	K	86.3	Confident	88.3	Confident	130 Å²	130	62.8 Å²	62.8	57%	0.565	33%	0.326	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-86.1	111.2	176.3	-170.7	178.5	179	-177.2	0	109.1	G173 Y176	K171-G173 WeakPolarHBondContact CE-O 3.37Å; K171-Y176 HydrophobicContact CB-CD1 4.1Å; K171-Y176 HydrophobicContact CB-CE1 3.89Å; K171-Y176 HydrophobicContact CG-CE1 4.45Å
172	E	80.9	Confident	88.1	Confident	87 Å²	87	61.5 Å²	61.5	41%	0.407	32%	0.317	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-107.4	102.9	175.9	-75.1	174.7	171.2	0	0	109	Q170 L174 H175 T177 H181	Q170-E172 HydrophobicContact CG-CG 4.16Å; Q170-E172 PolarHBondContact NE2-OE1 3.49Å; E172-L174 PolarHBondContact O-N 3.3Å; E172-H175 PolarHBondContact N-O 3.39Å; E172-H175 PolarHBondContact O-N 2.81Å; E172-T177 HydrophobicContact CB-CG2 4.24Å; E172-T177 PolarHBondContact OE2-OG1 2.83Å; E172-H181 IonicContact OE1-CE1 2.85Å; E172-H181 PolarHBondContact OE1-CE1 2.87Å; E172-H181 IonicContact OE1-NE2 3.24Å
173	G	80.5	Confident	87.9	Confident	69 Å²	69	62.9 Å²	62.9	71%	0.711	33%	0.326	S	S	*	.	T	Hydrogen-bonded Turn	trans	67	-118.5	-172.6	0	0	0	0	0	112.1	K171	K171-G173 WeakPolarHBondContact CE-O 3.37Å
174	L	81.2	Confident	87.8	Confident	153 Å²	153	73.2 Å²	73.2	80%	0.801	37%	0.366	S	S	*	.	T	Hydrogen-bonded Turn	trans	-89.8	-11.8	-178.7	-75.5	158.4	0	0	0	113.8	E172	E172-L174 PolarHBondContact O-N 3.3Å
175	H	83.8	Confident	87.7	Confident	81 Å²	81	76.3 Å²	76.3	38%	0.375	39%	0.392	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-122	151.5	-170.3	-64.5	-66.9	0	0	0	112.7	Q93 E172	Q93-H175 HydrophobicContact CB-CB 4.32Å; Q93-H175 PolarHBondContact OE1-ND1 3.1Å; Q93-H175 VanDerWaalsContact OE1-ND1 3.11Å; E172-H175 PolarHBondContact N-O 3.39Å; E172-H175 PolarHBondContact O-N 2.81Å
176	Y	87.8	Confident	87.7	Confident	112 Å²	112	76.3 Å²	76.3	44%	0.439	39%	0.389	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-83.1	130.1	167.2	-72.2	-85.2	0	0	0	110	W94 K171	W94-Y176 VanDerWaalsContact CB-O 3.3Å; W94-Y176 WeakPolarHBondContact CB-O 3.4Å; W94-Y176 PolarHBondContact N-O 3.07Å; W94-Y176 WeakPolarHBondContact O-CB 3.29Å; K171-Y176 HydrophobicContact CB-CD1 4.1Å; K171-Y176 HydrophobicContact CB-CE1 3.89Å; K171-Y176 HydrophobicContact CG-CE1 4.45Å
177	T	89.4	Confident	87.5	Confident	17 Å²	17	80.5 Å²	80.5	10%	0.104	41%	0.405	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-116.5	158.9	176.3	58.7	0	0	0	0	110.2	S169 Q170 E172	S169-T177 WeakPolarHBondContact CA-O 3.41Å; S169-T177 PolarHBondContact OG-O 3.45Å; S169-T177 VanDerWaalsContact OG-O 3.09Å; Q170-T177 PolarHBondContact N-O 3Å; Q170-T177 PolarHBondContact O-N 3.28Å; Q170-T177 PolarHBondContact O-OG1 3.44Å; E172-T177 HydrophobicContact CB-CG2 4.24Å; E172-T177 PolarHBondContact OE2-OG1 2.83Å
178	C	91.8	Very high	87.4	Confident	12 Å²	12	84.4 Å²	84.4	8%	0.081	42%	0.423	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-121.5	101.9	170.4	173.1	0	0	0	0	106.8	W94 C101	W94-C178 HydrophobicContact CB-CB 4.45Å; W94-C178 HydrophobicContact CD2-CB 3.48Å; W94-C178 VanDerWaalsContact CD2-CB 3.48Å; W94-C178 HydrophobicContact CE3-CB 3.61Å; W94-C178 HydrophobicContact CG-CB 3.84Å; W94-C178 HydrophobicContact CH2-CB 4.41Å; W94-C178 HydrophobicContact CZ2-CB 4.38Å; W94-C178 HydrophobicContact CZ3-CB 4.07Å; C101-C178 VanDerWaalsContact CA-SG 3.6Å; C101-C178 HydrophobicContact CB-CB 3.95Å; C101-C178 WeakPolarHBondContact CB-SG 3.49Å; C101-C178 VanDerWaalsContact SG-CA 3.59Å; C101-C178 WeakPolarHBondContact SG-CB 3.29Å; C101-C178 CovalentContact SG-SG 2.03Å; C101-C178 PolarHBondContact SG-SG 3.42Å
179	S	88	Confident	87.5	Confident	34 Å²	34	83.3 Å²	83.3	24%	0.238	42%	0.423	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-143.7	161.4	-170.7	54.4	0	0	0	0	111.6	T167 R168 H181	T167-S179 WeakPolarHBondContact CA-O 3.28Å; R168-S179 PolarHBondContact N-O 2.89Å; R168-S179 PolarHBondContact O-N 2.96Å; R168-S179 VanDerWaalsContact O-N 3.15Å; S179-H181 PolarHBondContact O-CD2 3.41Å; S179-H181 PolarHBondContact OG-CE1 3Å; S179-H181 PolarHBondContact OG-NE2 2.94Å
180	S	87.6	Confident	87.5	Confident	54 Å²	54	85.1 Å²	85.1	38%	0.378	43%	0.426	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-82.3	120.9	179.2	-64	0	0	0	0	110.9	T167	T167-S180 PolarHBondContact OG1-OG 3.47Å
181	H	87.8	Confident	87.6	Confident	58 Å²	58	83.4 Å²	83.4	27%	0.269	42%	0.417	S	S	.	.			trans	-112.6	110.7	176.2	-64	-69.3	0	0	0	110.6	F166 Q170 E172 S179	F166-H181 PolarHBondContact O-N 3.38Å; Q170-H181 WeakPolarHBondContact CG-NE2 3.09Å; Q170-H181 PolarHBondContact NE2-CE1 3.03Å; Q170-H181 PolarHBondContact NE2-NE2 2.94Å; E172-H181 IonicContact OE1-CE1 2.85Å; E172-H181 PolarHBondContact OE1-CE1 2.87Å; E172-H181 IonicContact OE1-NE2 3.24Å; S179-H181 PolarHBondContact O-CD2 3.41Å; S179-H181 PolarHBondContact OG-CE1 3Å; S179-H181 PolarHBondContact OG-NE2 2.94Å
182	F	89	Confident	87.9	Confident	38 Å²	38	79.1 Å²	79.1	17%	0.167	40%	0.4	C	S	.	.			trans	-90	148.5	175.9	-54.9	-61.7	0	0	0	111.2	F166 Y184 Y187 W190 K191 Q194	F166-F182 HydrophobicContact CB-CD1 3.89Å; F166-F182 HydrophobicContact CB-CE1 3.84Å; F166-F182 AromaticContact CD1-CD1 4Å; F166-F182 HydrophobicContact CD1-CD1 4Å; F166-F182 AromaticContact CD2-CD1 3.87Å; F166-F182 HydrophobicContact CD2-CD1 3.87Å; F166-F182 AromaticContact CD2-CE1 3.81Å; F166-F182 HydrophobicContact CD2-CE1 3.81Å; F166-F182 HydrophobicContact CE2-CD1 4.48Å; F166-F182 AromaticContact CG-CD1 3.63Å; F166-F182 HydrophobicContact CG-CD1 3.63Å; F166-F182 AromaticContact CG-CE1 3.85Å; F166-F182 HydrophobicContact CG-CE1 3.85Å; F182-Y184 PolarHBondContact O-N 3.05Å; F182-Y187 HydrophobicContact CB-CD2 3.87Å; F182-Y187 HydrophobicContact CB-CE2 4.35Å; F182-Y187 HydrophobicContact CD2-CD2 4.36Å; F182-Y187 HydrophobicContact CD2-CE2 4.08Å; F182-W190 HydrophobicContact CB-CB 4Å; F182-W190 HydrophobicContact CD1-CB 3.59Å; F182-W190 HydrophobicContact CE1-CB 4.28Å; F182-W190 HydrophobicContact CG-CB 3.88Å; F182-K191 HydrophobicContact CD2-CB 4.22Å; F182-K191 HydrophobicContact CE2-CB 4.21Å; F182-K191 HydrophobicContact CE2-CG 4.43Å; F182-Q194 HydrophobicContact CE1-CB 4.49Å; F182-Q194 HydrophobicContact CZ-CB 4.21Å; F182-Q194 HydrophobicContact CZ-CG 4.39Å
183	P	87.9	Confident	88.5	Confident	53 Å²	53	79.2 Å²	79.2	34%	0.344	40%	0.4	S	S	.	.			trans	-59.1	131.6	176.2	-20.7	31.2	0	0	0	111.4	F166 S185 Q186 Y187	F166-P183 HydrophobicContact CE1-CG 4.02Å; P183-S185 VanDerWaalsContact C-N 3.28Å; P183-S185 PolarHBondContact O-N 3.47Å; P183-Q186 CarbonylContact O-C 3.59Å; P183-Q186 PolarHBondContact O-N 2.88Å; P183-Q186 VanDerWaalsContact O-N 3.09Å; P183-Y187 VanDerWaalsContact O-CA 3.31Å; P183-Y187 WeakPolarHBondContact O-CA 3.38Å; P183-Y187 PolarHBondContact O-N 3.47Å
184	Y	86.3	Confident	89.1	Confident	218 Å²	218	76.5 Å²	76.5	86%	0.855	37%	0.369	S	S	*	.	G	3₁₀ helix	trans	-57.3	-39.3	-176.6	-174.5	-93.7	0	0	0	113	F182 Q186 Y187	F182-Y184 PolarHBondContact O-N 3.05Å; Y184-Q186 PolarHBondContact O-N 3.2Å; Y184-Y187 PolarHBondContact O-N 3.38Å
185	S	89.7	Confident	89.6	Confident	106 Å²	106	69.6 Å²	69.6	74%	0.741	33%	0.333	S	S	*	.	G	3₁₀ helix	trans	-61.7	-24.5	179.9	55.9	0	0	0	0	114.2	P183	P183-S185 VanDerWaalsContact C-N 3.28Å; P183-S185 PolarHBondContact O-N 3.47Å
186	Q	90.7	Very high	90.1	Very high	103 Å²	103	69.2 Å²	69.2	48%	0.481	33%	0.333	S	S	.	.	G	3₁₀ helix	trans	-134.7	28.7	-176.6	-66.6	-176.8	-24.6	0	0	111.6	P183 Y184 Q188 F189 W190	P183-Q186 CarbonylContact O-C 3.59Å; P183-Q186 PolarHBondContact O-N 2.88Å; P183-Q186 VanDerWaalsContact O-N 3.09Å; Y184-Q186 PolarHBondContact O-N 3.2Å; Q186-Q188 PolarHBondContact O-N 2.85Å; Q186-F189 HydrophobicContact CB-CB 4.42Å; Q186-F189 WeakPolarHBondContact O-CB 3.35Å; Q186-F189 PolarHBondContact O-N 2.71Å; Q186-F189 VanDerWaalsContact O-N 3.14Å; Q186-W190 VanDerWaalsContact O-CD1 3.3Å; Q186-W190 PolarHBondContact O-N 3.42Å; Q186-W190 VanDerWaalsContact O-N 3.09Å
187	Y	88.6	Confident	90.5	Very high	111 Å²	111	65 Å²	65	44%	0.435	32%	0.317	S	S	.	.	H	α-helix	trans	-55.5	-50.7	-170.6	177.2	-97.9	0	0	0	112.2	F182 P183 Y184 F189 W190 K191	F182-Y187 HydrophobicContact CB-CD2 3.87Å; F182-Y187 HydrophobicContact CB-CE2 4.35Å; F182-Y187 HydrophobicContact CD2-CD2 4.36Å; F182-Y187 HydrophobicContact CD2-CE2 4.08Å; P183-Y187 VanDerWaalsContact O-CA 3.31Å; P183-Y187 WeakPolarHBondContact O-CA 3.38Å; P183-Y187 PolarHBondContact O-N 3.47Å; Y184-Y187 PolarHBondContact O-N 3.38Å; Y187-F189 VanDerWaalsContact C-N 3.33Å; Y187-F189 PolarHBondContact O-N 3.36Å; Y187-W190 PolarHBondContact O-N 2.94Å; Y187-K191 HydrophobicContact CE1-CD 4.03Å; Y187-K191 VanDerWaalsContact O-CB 3.29Å; Y187-K191 WeakPolarHBondContact O-CB 3.45Å; Y187-K191 PolarHBondContact O-N 2.88Å
188	Q	88.7	Confident	90.7	Very high	86 Å²	86	64.5 Å²	64.5	40%	0.402	31%	0.314	S	S	.	.	H	α-helix	trans	-64.6	-37.3	-178.9	-166.8	63.4	35.9	0	0	112.4	Q186 N192	Q186-Q188 PolarHBondContact O-N 2.85Å; Q188-N192 PolarHBondContact NE2-OD1 2.91Å; Q188-N192 VanDerWaalsContact O-CB 3.22Å; Q188-N192 WeakPolarHBondContact O-CB 3.21Å; Q188-N192 PolarHBondContact O-N 3.43Å; Q188-N192 PolarHBondContact O-ND2 3.01Å; Q188-N192 PolarHBondContact O-OD1 3.24Å
189	F	91.9	Very high	90.8	Very high	124 Å²	124	64.6 Å²	64.6	54%	0.544	31%	0.314	S	S	.	.	H	α-helix	trans	-62.9	-51.1	178.8	175.7	-94.2	0	0	0	111.1	Q186 Y187 N192 F193	Q186-F189 HydrophobicContact CB-CB 4.42Å; Q186-F189 WeakPolarHBondContact O-CB 3.35Å; Q186-F189 PolarHBondContact O-N 2.71Å; Q186-F189 VanDerWaalsContact O-N 3.14Å; Y187-F189 VanDerWaalsContact C-N 3.33Å; Y187-F189 PolarHBondContact O-N 3.36Å; F189-N192 PolarHBondContact O-N 3.02Å; F189-F193 VanDerWaalsContact O-CB 3.27Å; F189-F193 WeakPolarHBondContact O-CB 3.47Å; F189-F193 PolarHBondContact O-N 3.14Å
190	W	92.1	Very high	91.1	Very high	63 Å²	63	67.2 Å²	67.2	24%	0.239	32%	0.324	C	S	.	.	H	α-helix	trans	-69.2	-38.1	-178.8	-73	108.1	0	0	0	112.7	F166 F182 Q186 Y187 F193 Q194	F166-W190 HydrophobicContact CD2-CE3 4.39Å; F166-W190 HydrophobicContact CE1-CD2 4.3Å; F166-W190 AromaticContact CE2-CD2 3.73Å; F166-W190 HydrophobicContact CE2-CD2 3.73Å; F166-W190 AromaticContact CE2-CE3 3.26Å; F166-W190 HydrophobicContact CE2-CE3 3.26Å; F166-W190 HydrophobicContact CE2-CG 4.39Å; F166-W190 HydrophobicContact CE2-CH2 4.2Å; F166-W190 AromaticContact CE2-CZ3 3.53Å; F166-W190 HydrophobicContact CE2-CZ3 3.53Å; F166-W190 AromaticContact CZ-CD2 3.4Å; F166-W190 HydrophobicContact CZ-CD2 3.4Å; F166-W190 VanDerWaalsContact CZ-CD2 3.4Å; F166-W190 AromaticContact CZ-CE2 3.66Å; F166-W190 AromaticContact CZ-CE3 3.41Å; F166-W190 HydrophobicContact CZ-CE3 3.41Å; F166-W190 VanDerWaalsContact CZ-CE3 3.41Å; F166-W190 HydrophobicContact CZ-CG 4.01Å; F166-W190 AromaticContact CZ-CH2 3.89Å; F166-W190 HydrophobicContact CZ-CH2 3.89Å; F166-W190 AromaticContact CZ-CZ2 3.9Å; F166-W190 HydrophobicContact CZ-CZ2 3.9Å; F166-W190 AromaticContact CZ-CZ3 3.66Å; F166-W190 HydrophobicContact CZ-CZ3 3.66Å; F182-W190 HydrophobicContact CB-CB 4Å; F182-W190 HydrophobicContact CD1-CB 3.59Å; F182-W190 HydrophobicContact CE1-CB 4.28Å; F182-W190 HydrophobicContact CG-CB 3.88Å; Q186-W190 VanDerWaalsContact O-CD1 3.3Å; Q186-W190 PolarHBondContact O-N 3.42Å; Q186-W190 VanDerWaalsContact O-N 3.09Å; Y187-W190 PolarHBondContact O-N 2.94Å; W190-F193 HydrophobicContact CE3-CD1 4.2Å; W190-F193 HydrophobicContact CZ3-CD1 4.22Å; W190-F193 HydrophobicContact CZ3-CE1 4.48Å; W190-F193 PolarHBondContact O-N 3.31Å; W190-Q194 WeakPolarHBondContact O-CB 3.48Å; W190-Q194 PolarHBondContact O-N 2.78Å
191	K	89.9	Confident	91.5	Very high	43 Å²	43	66.7 Å²	66.7	19%	0.187	32%	0.317	C	S	.	.	H	α-helix	trans	-59.1	-50.3	172.8	-169.6	-173.2	178.6	-168.6	0	110.8	F182 Y187 Q194 T195 T259	F182-K191 HydrophobicContact CD2-CB 4.22Å; F182-K191 HydrophobicContact CE2-CB 4.21Å; F182-K191 HydrophobicContact CE2-CG 4.43Å; Y187-K191 HydrophobicContact CE1-CD 4.03Å; Y187-K191 VanDerWaalsContact O-CB 3.29Å; Y187-K191 WeakPolarHBondContact O-CB 3.45Å; Y187-K191 PolarHBondContact O-N 2.88Å; K191-Q194 PolarHBondContact O-N 3.18Å; K191-T195 PolarHBondContact O-N 3.32Å; K191-T195 VanDerWaalsContact O-N 3.1Å; K191-T195 PolarHBondContact O-OG1 2.79Å; K191-T259 HydrophobicContact CD-CG2 4.43Å; K191-T259 HydrophobicContact CG-CG2 4.17Å
192	N	92.4	Very high	91.6	Very high	39 Å²	39	64 Å²	64	21%	0.209	30%	0.304	C	S	.	.	H	α-helix	trans	-62.5	-46	177.8	-71.4	-6.9	0	0	0	111.8	Q188 F189 Q194 T195 L196 T259	Q188-N192 PolarHBondContact NE2-OD1 2.91Å; Q188-N192 VanDerWaalsContact O-CB 3.22Å; Q188-N192 WeakPolarHBondContact O-CB 3.21Å; Q188-N192 PolarHBondContact O-N 3.43Å; Q188-N192 PolarHBondContact O-ND2 3.01Å; Q188-N192 PolarHBondContact O-OD1 3.24Å; F189-N192 PolarHBondContact O-N 3.02Å; N192-Q194 PolarHBondContact O-N 3.03Å; N192-T195 PolarHBondContact O-N 3.05Å; N192-L196 VanDerWaalsContact O-CB 3.31Å; N192-L196 WeakPolarHBondContact O-CB 3.5Å; N192-L196 VanDerWaalsContact O-CG 3.26Å; N192-L196 WeakPolarHBondContact O-CG 3.37Å; N192-L196 PolarHBondContact O-N 3.24Å; N192-T259 WeakPolarHBondContact OD1-CG2 3.42Å
193	F	93.9	Very high	91.6	Very high	89 Å²	89	63.9 Å²	63.9	39%	0.39	31%	0.306	S	S	.	.	H	α-helix	trans	-59.1	-47	179.6	177.5	-98.4	0	0	0	111.6	P162 F189 W190 K197	P162-F193 HydrophobicContact CG-CE1 4.27Å; F189-F193 VanDerWaalsContact O-CB 3.27Å; F189-F193 WeakPolarHBondContact O-CB 3.47Å; F189-F193 PolarHBondContact O-N 3.14Å; W190-F193 HydrophobicContact CE3-CD1 4.2Å; W190-F193 HydrophobicContact CZ3-CD1 4.22Å; W190-F193 HydrophobicContact CZ3-CE1 4.48Å; W190-F193 PolarHBondContact O-N 3.31Å; F193-K197 WeakPolarHBondContact O-CB 3.45Å; F193-K197 PolarHBondContact O-N 3.34Å
194	Q	92.1	Very high	91.9	Very high	13 Å²	13	65.1 Å²	65.1	6%	0.061	31%	0.312	C	S	.	.	H	α-helix	trans	-63.8	-44.6	-179.9	-173	71	-11.3	0	0	111.6	F182 W190 K191 N192 I198	F182-Q194 HydrophobicContact CE1-CB 4.49Å; F182-Q194 HydrophobicContact CZ-CB 4.21Å; F182-Q194 HydrophobicContact CZ-CG 4.39Å; W190-Q194 WeakPolarHBondContact O-CB 3.48Å; W190-Q194 PolarHBondContact O-N 2.78Å; K191-Q194 PolarHBondContact O-N 3.18Å; N192-Q194 PolarHBondContact O-N 3.03Å; Q194-I198 HydrophobicContact CG-CD1 4.23Å; Q194-I198 WeakPolarHBondContact O-CG1 3.28Å; Q194-I198 PolarHBondContact O-N 2.75Å; Q194-I198 VanDerWaalsContact O-N 3.14Å
195	T	92.8	Very high	92.2	Very high	8 Å²	8	57.6 Å²	57.6	5%	0.049	29%	0.286	C	S	.	.	H	α-helix	trans	-64.2	-50.4	177.4	-66.2	0	0	0	0	111.9	K191 N192 K197 I198 V199 L255 L256 T259	K191-T195 PolarHBondContact O-N 3.32Å; K191-T195 VanDerWaalsContact O-N 3.1Å; K191-T195 PolarHBondContact O-OG1 2.79Å; N192-T195 PolarHBondContact O-N 3.05Å; T195-K197 VanDerWaalsContact C-N 3.29Å; T195-K197 PolarHBondContact O-N 3.13Å; T195-I198 PolarHBondContact O-N 2.95Å; T195-V199 HydrophobicContact CG2-CG2 4.25Å; T195-V199 WeakPolarHBondContact O-CG2 3.42Å; T195-V199 PolarHBondContact O-N 3.26Å; T195-L255 HydrophobicContact CG2-CD2 4.35Å; T195-L255 HydrophobicContact CG2-CG 4.02Å; T195-L256 HydrophobicContact CG2-CD1 4.39Å; T195-T259 WeakPolarHBondContact CB-OG1 3.36Å; T195-T259 HydrophobicContact CG2-CG2 4.14Å; T195-T259 WeakPolarHBondContact CG2-OG1 3.4Å; T195-T259 PolarHBondContact OG1-OG1 3.3Å
196	L	94.5	Very high	92.2	Very high	72 Å²	72	52.5 Å²	52.5	38%	0.377	25%	0.251	S	S	.	.	H	α-helix	trans	-61.2	-40.1	179.9	-71.5	175.4	0	0	0	111.2	N192 I198 V199 I200 F260	N192-L196 VanDerWaalsContact O-CB 3.31Å; N192-L196 WeakPolarHBondContact O-CB 3.5Å; N192-L196 VanDerWaalsContact O-CG 3.26Å; N192-L196 WeakPolarHBondContact O-CG 3.37Å; N192-L196 PolarHBondContact O-N 3.24Å; L196-I198 PolarHBondContact O-N 3.04Å; L196-V199 PolarHBondContact O-N 2.93Å; L196-I200 HydrophobicContact CB-CD1 4.22Å; L196-I200 WeakPolarHBondContact O-CB 3.46Å; L196-I200 WeakPolarHBondContact O-CD1 3.31Å; L196-I200 WeakPolarHBondContact O-CG1 3.2Å; L196-I200 PolarHBondContact O-N 3.09Å; L196-F260 HydrophobicContact CD2-CE2 4.34Å; L196-F260 HydrophobicContact CD2-CZ 4.39Å
197	K	95	Very high	92.1	Very high	23 Å²	23	49.5 Å²	49.5	10%	0.1	24%	0.24	C	C	.	.	H	α-helix	trans	-57.7	-49.6	174.6	-178.9	-159.1	73.5	179.1	0	111.7	F113 A159 F193 T195 L201	F113-K197 HydrophobicContact CZ-CD 4.46Å; A159-K197 PolarHBondContact O-NZ 3.47Å; F193-K197 WeakPolarHBondContact O-CB 3.45Å; F193-K197 PolarHBondContact O-N 3.34Å; T195-K197 VanDerWaalsContact C-N 3.29Å; T195-K197 PolarHBondContact O-N 3.13Å; K197-L201 HydrophobicContact CG-CD1 3.89Å; K197-L201 WeakPolarHBondContact O-CB 3.47Å; K197-L201 WeakPolarHBondContact O-CG 3.22Å; K197-L201 PolarHBondContact O-N 2.82Å
198	I	93.4	Very high	92.2	Very high	8 Å²	8	49 Å²	49	4%	0.041	24%	0.244	C	C	.	.	H	α-helix	trans	-62.8	-47.1	180	-68	165.7	0	0	0	110.3	F109 F112 F113 Q194 T195 L196 G202 N252 L255	F109-I198 HydrophobicContact CE1-CD1 4.03Å; F112-I198 HydrophobicContact CE1-CG2 4.2Å; F112-I198 HydrophobicContact CZ-CG2 4.33Å; F113-I198 HydrophobicContact CZ-CG1 4.18Å; Q194-I198 HydrophobicContact CG-CD1 4.23Å; Q194-I198 WeakPolarHBondContact O-CG1 3.28Å; Q194-I198 PolarHBondContact O-N 2.75Å; Q194-I198 VanDerWaalsContact O-N 3.14Å; T195-I198 PolarHBondContact O-N 2.95Å; L196-I198 PolarHBondContact O-N 3.04Å; I198-G202 VanDerWaalsContact O-CA 3.27Å; I198-G202 WeakPolarHBondContact O-CA 3.24Å; I198-G202 PolarHBondContact O-N 2.94Å; I198-N252 WeakPolarHBondContact CG2-OD1 3.18Å; I198-N252 PolarHBondContact O-OD1 3.4Å; I198-L255 HydrophobicContact CB-CD2 4.07Å; I198-L255 HydrophobicContact CD1-CD2 4.03Å; I198-L255 HydrophobicContact CG2-CD2 3.82Å
199	V	94.1	Very high	92.3	Very high	13 Å²	13	45.9 Å²	45.9	8%	0.079	23%	0.231	C	C	.	.	H	α-helix	trans	-67.1	-44.7	-179	173.2	0	0	0	0	111.8	T195 L196 L203 V204 N252 L256	T195-V199 HydrophobicContact CG2-CG2 4.25Å; T195-V199 WeakPolarHBondContact O-CG2 3.42Å; T195-V199 PolarHBondContact O-N 3.26Å; L196-V199 PolarHBondContact O-N 2.93Å; V199-L203 HydrophobicContact CG1-CB 4.44Å; V199-L203 HydrophobicContact CG1-CD2 4.43Å; V199-L203 CarbonylContact O-C 3.58Å; V199-L203 VanDerWaalsContact O-CA 3.3Å; V199-L203 WeakPolarHBondContact O-CA 3.38Å; V199-L203 VanDerWaalsContact O-CB 3.27Å; V199-L203 WeakPolarHBondContact O-CB 3.29Å; V199-L203 PolarHBondContact O-N 3.39Å; V199-V204 HydrophobicContact CG1-CG2 4.28Å; V199-V204 PolarHBondContact O-N 3.25Å; V199-N252 HydrophobicContact CG2-CB 4.47Å; V199-L256 HydrophobicContact CG2-CB 4.45Å; V199-L256 HydrophobicContact CG2-CD1 4.4Å
200	I	95.1	Very high	92	Very high	89 Å²	89	41.2 Å²	41.2	46%	0.456	21%	0.211	S	C	.	.	I	π-helix	trans	-64.9	-50.4	-178.8	-69.4	166.3	0	0	0	110.2	L196 V204 L205	L196-I200 HydrophobicContact CB-CD1 4.22Å; L196-I200 WeakPolarHBondContact O-CB 3.46Å; L196-I200 WeakPolarHBondContact O-CD1 3.31Å; L196-I200 WeakPolarHBondContact O-CG1 3.2Å; L196-I200 PolarHBondContact O-N 3.09Å; I200-V204 PolarHBondContact O-N 3.45Å; I200-L205 VanDerWaalsContact O-CB 3.31Å; I200-L205 WeakPolarHBondContact O-CB 3.36Å; I200-L205 PolarHBondContact O-N 2.96Å
201	L	94.7	Very high	91.8	Very high	43 Å²	43	43 Å²	43	23%	0.225	23%	0.229	C	C	.	.	I	π-helix	trans	-76.2	-36.2	-176.2	-61.7	177.5	0	0	0	112.7	F113 F117 A159 K197 L205 P206	F113-L201 HydrophobicContact CD1-CB 4.3Å; F113-L201 HydrophobicContact CD1-CD1 4.25Å; F113-L201 HydrophobicContact CE1-CB 4.05Å; F113-L201 HydrophobicContact CE1-CD1 3.96Å; F117-L201 HydrophobicContact CE1-CB 4.47Å; F117-L201 HydrophobicContact CE1-CD2 4.46Å; F117-L201 HydrophobicContact CZ-CD1 4.32Å; A159-L201 HydrophobicContact CB-CD1 4.42Å; K197-L201 HydrophobicContact CG-CD1 3.89Å; K197-L201 WeakPolarHBondContact O-CB 3.47Å; K197-L201 WeakPolarHBondContact O-CG 3.22Å; K197-L201 PolarHBondContact O-N 2.82Å; L201-L205 HydrophobicContact CD2-CD2 4.28Å; L201-P206 WeakPolarHBondContact O-CD 3.32Å
202	G	90	Very high	91.8	Very high	1 Å²	1	45.5 Å²	45.5	1%	0.01	24%	0.243	C	C	.	.	I	π-helix	trans	-92.8	-25	-173.7	0	0	0	0	0	115	I198 Y244	I198-G202 VanDerWaalsContact O-CA 3.27Å; I198-G202 WeakPolarHBondContact O-CA 3.24Å; I198-G202 PolarHBondContact O-N 2.94Å; G202-Y244 WeakPolarHBondContact O-CE1 3.46Å; G202-Y244 PolarHBondContact O-OH 3.45Å; G202-Y244 VanDerWaalsContact O-OH 3.04Å
203	L	90.9	Very high	91.6	Very high	37 Å²	37	44 Å²	44	19%	0.194	24%	0.236	C	C	.	.	I	π-helix	trans	-124.1	-35.9	-176.5	-177.5	63.9	0	0	0	114.2	V199 P207 F245 A249 N252 I253	V199-L203 HydrophobicContact CG1-CB 4.44Å; V199-L203 HydrophobicContact CG1-CD2 4.43Å; V199-L203 CarbonylContact O-C 3.58Å; V199-L203 VanDerWaalsContact O-CA 3.3Å; V199-L203 WeakPolarHBondContact O-CA 3.38Å; V199-L203 VanDerWaalsContact O-CB 3.27Å; V199-L203 WeakPolarHBondContact O-CB 3.29Å; V199-L203 PolarHBondContact O-N 3.39Å; L203-P207 WeakPolarHBondContact O-CD 3.44Å; L203-P207 WeakPolarHBondContact O-CG 3.34Å; L203-F245 HydrophobicContact CD1-CD1 4.27Å; L203-A249 HydrophobicContact CD1-CB 3.64Å; L203-N252 HydrophobicContact CB-CB 3.96Å; L203-N252 HydrophobicContact CD2-CB 3.76Å; L203-N252 HydrophobicContact CG-CB 4.35Å; L203-I253 HydrophobicContact CD2-CG1 4.22Å
204	V	93.1	Very high	91	Very high	79 Å²	79	41.3 Å²	41.3	48%	0.479	22%	0.223	S	C	.	.	I	π-helix	trans	-89.9	-45.7	-175	179.9	0	0	0	0	112.6	V199 I200 P207 L208	V199-V204 HydrophobicContact CG1-CG2 4.28Å; V199-V204 PolarHBondContact O-N 3.25Å; I200-V204 PolarHBondContact O-N 3.45Å; V204-P207 WeakPolarHBondContact O-CD 3.48Å; V204-L208 WeakPolarHBondContact O-CB 3.29Å; V204-L208 PolarHBondContact O-N 3.4Å
205	L	93.1	Very high	90.7	Very high	59 Å²	59	44 Å²	44	31%	0.309	24%	0.244	S	C	.	.	H	α-helix	trans	-61.9	-46.1	-179.2	178.7	68.6	0	0	0	112.8	F117 I120 I200 L201 L208 V209	F117-L205 HydrophobicContact CE1-CD2 4.43Å; I120-L205 HydrophobicContact CD1-CD2 3.88Å; I120-L205 HydrophobicContact CD1-CG 3.95Å; I200-L205 VanDerWaalsContact O-CB 3.31Å; I200-L205 WeakPolarHBondContact O-CB 3.36Å; I200-L205 PolarHBondContact O-N 2.96Å; L201-L205 HydrophobicContact CD2-CD2 4.28Å; L205-L208 PolarHBondContact O-N 2.93Å; L205-V209 HydrophobicContact CD1-CG2 4.39Å; L205-V209 WeakPolarHBondContact O-CG2 3.27Å; L205-V209 PolarHBondContact O-N 2.93Å; L205-V209 VanDerWaalsContact O-N 3.08Å
206	P	89.7	Confident	90.3	Very high	0 Å²	0	44.3 Å²	44.3	0%	0	25%	0.249	C	C	.	.	H	α-helix	trans	-65.9	-44	-175.7	-14.8	28.1	0	0	0	114.2	I116 I120 L201 L208 V209 M210 M241 F245	I116-P206 HydrophobicContact CD1-CB 3.64Å; I116-P206 HydrophobicContact CD1-CG 3.46Å; I116-P206 VanDerWaalsContact CD1-CG 3.46Å; I116-P206 HydrophobicContact CG1-CB 4.09Å; I116-P206 HydrophobicContact CG1-CG 3.36Å; I120-P206 HydrophobicContact CD1-CB 4.25Å; I120-P206 HydrophobicContact CD1-CG 4.09Å; I120-P206 HydrophobicContact CG1-CB 4.21Å; L201-P206 WeakPolarHBondContact O-CD 3.32Å; P206-L208 VanDerWaalsContact C-N 3.35Å; P206-V209 PolarHBondContact O-N 3.38Å; P206-M210 WeakPolarHBondContact O-CB 3.43Å; P206-M210 PolarHBondContact O-N 3.38Å; P206-M241 HydrophobicContact CB-SD 4.17Å; P206-F245 HydrophobicContact CB-CE1 4.06Å; P206-F245 HydrophobicContact CB-CZ 3.8Å
207	P	87.4	Confident	89.7	Confident	40 Å²	40	41 Å²	41	26%	0.26	23%	0.231	S	C	.	.	H	α-helix	trans	-66.2	-35.1	174.1	-14.4	23	0	0	0	112.8	L203 V204 V209 M210 V211 F245	L203-P207 WeakPolarHBondContact O-CD 3.44Å; L203-P207 WeakPolarHBondContact O-CG 3.34Å; V204-P207 WeakPolarHBondContact O-CD 3.48Å; P207-V209 VanDerWaalsContact C-N 3.35Å; P207-V209 PolarHBondContact O-N 3.41Å; P207-M210 CarbonylContact O-C 3.45Å; P207-M210 WeakPolarHBondContact O-CA 3.45Å; P207-M210 VanDerWaalsContact O-CB 3.31Å; P207-M210 WeakPolarHBondContact O-CB 3.45Å; P207-M210 PolarHBondContact O-N 3.14Å; P207-M210 VanDerWaalsContact O-N 3.12Å; P207-V211 WeakPolarHBondContact O-CG2 3.45Å; P207-V211 PolarHBondContact O-N 3.26Å; P207-F245 HydrophobicContact CB-CZ 4.02Å; P207-F245 HydrophobicContact CG-CD1 4.42Å; P207-F245 HydrophobicContact CG-CE1 3.48Å; P207-F245 VanDerWaalsContact CG-CE1 3.48Å; P207-F245 HydrophobicContact CG-CE2 4.19Å; P207-F245 HydrophobicContact CG-CZ 3.35Å
208	L	91.6	Very high	89.1	Confident	100 Å²	100	44.8 Å²	44.8	52%	0.524	25%	0.252	S	S	.	.	H	α-helix	trans	-59.5	-49.2	176.4	178.7	63.5	0	0	0	110.5	V204 L205 P206 M210 V211 I212	V204-L208 WeakPolarHBondContact O-CB 3.29Å; V204-L208 PolarHBondContact O-N 3.4Å; L205-L208 PolarHBondContact O-N 2.93Å; P206-L208 VanDerWaalsContact C-N 3.35Å; L208-M210 VanDerWaalsContact C-N 3.27Å; L208-M210 PolarHBondContact O-N 3.1Å; L208-V211 PolarHBondContact O-N 3.1Å; L208-I212 HydrophobicContact CD1-CD1 4.1Å; L208-I212 HydrophobicContact CG-CD1 4.15Å; L208-I212 WeakPolarHBondContact O-CD1 3.48Å; L208-I212 WeakPolarHBondContact O-CG1 3.18Å; L208-I212 PolarHBondContact O-N 2.7Å
209	V	90.9	Very high	88.6	Confident	21 Å²	21	52.2 Å²	52.2	13%	0.127	28%	0.284	C	S	.	.	H	α-helix	trans	-59.7	-41.8	173.7	175	0	0	0	0	110.6	I120 T123 I124 L205 P206 P207 I212 C213	I120-V209 HydrophobicContact CG2-CG1 4.25Å; I120-V209 HydrophobicContact CG2-CG2 4.17Å; T123-V209 HydrophobicContact CG2-CG1 4.29Å; I124-V209 HydrophobicContact CD1-CG1 4.45Å; I124-V209 HydrophobicContact CG1-CG1 4.03Å; L205-V209 HydrophobicContact CD1-CG2 4.39Å; L205-V209 WeakPolarHBondContact O-CG2 3.27Å; L205-V209 PolarHBondContact O-N 2.93Å; L205-V209 VanDerWaalsContact O-N 3.08Å; P206-V209 PolarHBondContact O-N 3.38Å; P207-V209 VanDerWaalsContact C-N 3.35Å; P207-V209 PolarHBondContact O-N 3.41Å; V209-I212 PolarHBondContact O-N 2.78Å; V209-C213 VanDerWaalsContact O-CB 3.28Å; V209-C213 WeakPolarHBondContact O-CB 3.38Å; V209-C213 PolarHBondContact O-N 3.04Å; V209-C213 PolarHBondContact O-SG 3.34Å; V209-C213 VanDerWaalsContact O-SG 3.36Å
210	M	84.9	Confident	87.7	Confident	25 Å²	25	53.1 Å²	53.1	12%	0.123	29%	0.29	C	S	.	.	H	α-helix	trans	-59.1	-51.6	179.3	-167.7	-173.8	-162.2	0	0	111.9	P206 P207 L208 I212 C213 Y214 F238 M241 I242 F245	P206-M210 WeakPolarHBondContact O-CB 3.43Å; P206-M210 PolarHBondContact O-N 3.38Å; P207-M210 CarbonylContact O-C 3.45Å; P207-M210 WeakPolarHBondContact O-CA 3.45Å; P207-M210 VanDerWaalsContact O-CB 3.31Å; P207-M210 WeakPolarHBondContact O-CB 3.45Å; P207-M210 PolarHBondContact O-N 3.14Å; P207-M210 VanDerWaalsContact O-N 3.12Å; L208-M210 VanDerWaalsContact C-N 3.27Å; L208-M210 PolarHBondContact O-N 3.1Å; M210-I212 VanDerWaalsContact C-N 3.32Å; M210-I212 PolarHBondContact O-N 3.43Å; M210-C213 PolarHBondContact O-N 3.46Å; M210-Y214 HydrophobicContact CB-CD2 4.37Å; M210-Y214 HydrophobicContact CE-CD2 4.4Å; M210-Y214 HydrophobicContact CE-CE2 4.21Å; M210-Y214 HydrophobicContact CG-CD2 3.45Å; M210-Y214 VanDerWaalsContact CG-CD2 3.45Å; M210-Y214 HydrophobicContact CG-CE2 3.78Å; M210-Y214 HydrophobicContact CG-CG 4.46Å; M210-Y214 VanDerWaalsContact O-CB 3.3Å; M210-Y214 WeakPolarHBondContact O-CB 3.13Å; M210-Y214 VanDerWaalsContact O-CD2 3.31Å; M210-Y214 WeakPolarHBondContact O-CD2 3.41Å; M210-Y214 PolarHBondContact O-N 3.38Å; M210-F238 HydrophobicContact CE-CD2 3.35Å; M210-F238 HydrophobicContact CE-CE2 3.39Å; M210-F238 HydrophobicContact CE-CG 4.35Å; M210-F238 HydrophobicContact CE-CZ 4.41Å; M210-M241 HydrophobicContact CE-CB 4.05Å; M210-M241 HydrophobicContact CE-CG 3.8Å; M210-M241 HydrophobicContact CG-CG 4.33Å; M210-M241 HydrophobicContact SD-CG 3.72Å; M210-I242 HydrophobicContact CE-CG1 4.24Å; M210-F245 HydrophobicContact SD-CE2 3.97Å
211	V	88.1	Confident	86.7	Confident	100 Å²	100	49.8 Å²	49.8	61%	0.606	27%	0.273	S	S	*	.	H	α-helix	trans	-59.7	-44.3	-178.8	171.5	0	0	0	0	110.7	P207 L208 S215	P207-V211 WeakPolarHBondContact O-CG2 3.45Å; P207-V211 PolarHBondContact O-N 3.26Å; L208-V211 PolarHBondContact O-N 3.1Å; V211-S215 WeakPolarHBondContact O-CB 3.22Å; V211-S215 PolarHBondContact O-N 3.27Å; V211-S215 VanDerWaalsContact O-N 3.09Å; V211-S215 PolarHBondContact O-OG 2.97Å
212	I	89.9	Confident	85.7	Confident	96 Å²	96	54.3 Å²	54.3	49%	0.492	30%	0.296	S	S	.	.	H	α-helix	trans	-65.2	-49.4	178.7	-63.5	166.7	0	0	0	110.9	L208 V209 M210 S215 G216	L208-I212 HydrophobicContact CD1-CD1 4.1Å; L208-I212 HydrophobicContact CG-CD1 4.15Å; L208-I212 WeakPolarHBondContact O-CD1 3.48Å; L208-I212 WeakPolarHBondContact O-CG1 3.18Å; L208-I212 PolarHBondContact O-N 2.7Å; V209-I212 PolarHBondContact O-N 2.78Å; M210-I212 VanDerWaalsContact C-N 3.32Å; M210-I212 PolarHBondContact O-N 3.43Å; I212-S215 PolarHBondContact O-OG 3.35Å; I212-G216 PolarHBondContact O-N 2.99Å
213	C	87.5	Confident	85	Confident	7 Å²	7	65 Å²	65	5%	0.047	34%	0.336	C	S	.	.	H	α-helix	trans	-68.9	-46.5	-176.7	-72.3	0	0	0	0	112.2	T123 Y127 V209 M210 G216 I217	T123-C213 HydrophobicContact CG2-CB 3.84Å; Y127-C213 VanDerWaalsContact CD2-CA 3.45Å; Y127-C213 HydrophobicContact CD2-CB 3.85Å; Y127-C213 VanDerWaalsContact CD2-O 3.24Å; Y127-C213 WeakPolarHBondContact CD2-O 3.47Å; Y127-C213 HydrophobicContact CG-CB 4.06Å; V209-C213 VanDerWaalsContact O-CB 3.28Å; V209-C213 WeakPolarHBondContact O-CB 3.38Å; V209-C213 PolarHBondContact O-N 3.04Å; V209-C213 PolarHBondContact O-SG 3.34Å; V209-C213 VanDerWaalsContact O-SG 3.36Å; M210-C213 PolarHBondContact O-N 3.46Å; C213-G216 PolarHBondContact O-N 3.29Å; C213-I217 WeakPolarHBondContact O-CB 3.22Å; C213-I217 WeakPolarHBondContact O-CD1 3.28Å; C213-I217 VanDerWaalsContact O-CG1 3.25Å; C213-I217 WeakPolarHBondContact O-CG1 3.44Å; C213-I217 PolarHBondContact O-N 2.95Å
214	Y	82.9	Confident	83.7	Confident	33 Å²	33	66.2 Å²	66.2	13%	0.129	35%	0.347	C	S	.	.	H	α-helix	trans	-72.3	-32.2	-176.3	-81.3	-86.3	0	0	0	113	T123 M210 I217 L218 V234 F238	T123-Y214 HydrophobicContact CG2-CE2 4.04Å; M210-Y214 HydrophobicContact CB-CD2 4.37Å; M210-Y214 HydrophobicContact CE-CD2 4.4Å; M210-Y214 HydrophobicContact CE-CE2 4.21Å; M210-Y214 HydrophobicContact CG-CD2 3.45Å; M210-Y214 VanDerWaalsContact CG-CD2 3.45Å; M210-Y214 HydrophobicContact CG-CE2 3.78Å; M210-Y214 HydrophobicContact CG-CG 4.46Å; M210-Y214 VanDerWaalsContact O-CB 3.3Å; M210-Y214 WeakPolarHBondContact O-CB 3.13Å; M210-Y214 VanDerWaalsContact O-CD2 3.31Å; M210-Y214 WeakPolarHBondContact O-CD2 3.41Å; M210-Y214 PolarHBondContact O-N 3.38Å; Y214-I217 PolarHBondContact O-N 3Å; Y214-L218 VanDerWaalsContact O-CB 3.26Å; Y214-L218 WeakPolarHBondContact O-CB 3.46Å; Y214-L218 PolarHBondContact O-N 3.48Å; Y214-V234 HydrophobicContact CD1-CG1 4.28Å; Y214-V234 HydrophobicContact CE1-CG1 3.68Å; Y214-V234 PolarHBondContact OH-O 3.2Å; Y214-F238 AromaticContact CD1-CD2 3.95Å; Y214-F238 HydrophobicContact CD1-CD2 3.95Å; Y214-F238 HydrophobicContact CE1-CB 3.8Å; Y214-F238 AromaticContact CE1-CD2 3.57Å; Y214-F238 HydrophobicContact CE1-CD2 3.57Å; Y214-F238 HydrophobicContact CE1-CG 4.09Å; Y214-F238 HydrophobicContact CE2-CD2 4.21Å; Y214-F238 HydrophobicContact CG-CD2 4.43Å; Y214-F238 AromaticContact CZ-CD2 3.73Å; Y214-F238 WeakPolarHBondContact OH-CA 3.19Å; Y214-F238 WeakPolarHBondContact OH-CB 3.47Å; Y214-F238 PolarHBondContact OH-N 2.81Å
215	S	85	Confident	82.1	Confident	71 Å²	71	73.3 Å²	73.3	50%	0.497	37%	0.365	S	S	.	.	H	α-helix	trans	-61.4	-45.1	172.6	58.6	0	0	0	0	111.4	V211 I212 L218 K219	V211-S215 WeakPolarHBondContact O-CB 3.22Å; V211-S215 PolarHBondContact O-N 3.27Å; V211-S215 VanDerWaalsContact O-N 3.09Å; V211-S215 PolarHBondContact O-OG 2.97Å; I212-S215 PolarHBondContact O-OG 3.35Å; S215-L218 PolarHBondContact O-N 3.04Å; S215-K219 WeakPolarHBondContact O-CB 3.08Å; S215-K219 PolarHBondContact O-N 2.98Å
216	G	84.2	Confident	80.3	Confident	14 Å²	14	77.2 Å²	77.2	14%	0.144	39%	0.387	C	S	.	.	H	α-helix	trans	-67.8	-37.8	175.7	0	0	0	0	0	113.8	V131 I212 C213 T220	V131-G216 WeakPolarHBondContact CG2-O 3.44Å; I212-G216 PolarHBondContact O-N 2.99Å; C213-G216 PolarHBondContact O-N 3.29Å; G216-T220 WeakPolarHBondContact O-CB 3.07Å; G216-T220 PolarHBondContact O-N 2.95Å; G216-T220 VanDerWaalsContact O-N 3.11Å; G216-T220 PolarHBondContact O-OG1 2.8Å
217	I	82.6	Confident	79.1	Confident	3 Å²	3	82.7 Å²	82.7	2%	0.015	41%	0.412	C	S	.	.	H	α-helix	trans	-62.4	-48.2	173.4	-72.3	164.4	0	0	0	110.3	Y127 V130 V131 C213 Y214 T220 L221 V234	Y127-I217 HydrophobicContact CD2-CG1 4.15Å; V130-I217 HydrophobicContact CB-CG1 4.28Å; V130-I217 HydrophobicContact CG1-CB 4.49Å; V130-I217 HydrophobicContact CG1-CG1 4.22Å; V130-I217 HydrophobicContact CG1-CG2 4.23Å; V131-I217 HydrophobicContact CG2-CG1 4.15Å; C213-I217 WeakPolarHBondContact O-CB 3.22Å; C213-I217 WeakPolarHBondContact O-CD1 3.28Å; C213-I217 VanDerWaalsContact O-CG1 3.25Å; C213-I217 WeakPolarHBondContact O-CG1 3.44Å; C213-I217 PolarHBondContact O-N 2.95Å; Y214-I217 PolarHBondContact O-N 3Å; I217-T220 PolarHBondContact O-N 3.36Å; I217-L221 HydrophobicContact CG2-CD1 3.47Å; I217-L221 VanDerWaalsContact CG2-CD1 3.47Å; I217-L221 HydrophobicContact CG2-CG 4.16Å; I217-L221 WeakPolarHBondContact O-CB 3.45Å; I217-L221 VanDerWaalsContact O-CG 3.28Å; I217-L221 WeakPolarHBondContact O-CG 3.45Å; I217-L221 PolarHBondContact O-N 2.83Å; I217-V234 HydrophobicContact CG2-CG1 3.95Å; I217-V234 HydrophobicContact CG2-CG2 3.97Å
218	L	81.3	Confident	77.9	Confident	102 Å²	102	89 Å²	89	53%	0.534	44%	0.436	S	S	.	.	H	α-helix	trans	-63.4	-45.2	-178.3	-172.9	63.1	0	0	0	111	Y214 S215 T220 L221 L222	Y214-L218 VanDerWaalsContact O-CB 3.26Å; Y214-L218 WeakPolarHBondContact O-CB 3.46Å; Y214-L218 PolarHBondContact O-N 3.48Å; S215-L218 PolarHBondContact O-N 3.04Å; L218-T220 VanDerWaalsContact C-N 3.26Å; L218-T220 PolarHBondContact O-N 3.41Å; L218-L221 PolarHBondContact O-N 3.42Å; L218-L221 VanDerWaalsContact O-N 3.17Å; L218-L222 HydrophobicContact CD1-CG 4.42Å; L218-L222 HydrophobicContact CG-CD1 4.09Å; L218-L222 HydrophobicContact CG-CG 4.43Å; L218-L222 WeakPolarHBondContact O-CB 3.42Å; L218-L222 VanDerWaalsContact O-CG 3.28Å; L218-L222 WeakPolarHBondContact O-CG 3.3Å; L218-L222 PolarHBondContact O-N 3.4Å
219	K	83.1	Confident	76.3	Confident	164 Å²	164	91.1 Å²	91.1	71%	0.713	44%	0.441	S	S	*	.	H	α-helix	trans	-56	-41.4	174.7	-171.9	176.1	-177.8	176.4	0	112.1	S215 R223	S215-K219 WeakPolarHBondContact O-CB 3.08Å; S215-K219 PolarHBondContact O-N 2.98Å; K219-R223 PolarHBondContact O-N 3.37Å
220	T	76.7	Confident	75.1	Confident	32 Å²	32	92.6 Å²	92.6	20%	0.196	44%	0.444	C	S	.	.	H	α-helix	trans	-75.7	-31.9	179.6	-52.8	0	0	0	0	112.9	V130 G216 I217 L218 C224 R230	V130-T220 HydrophobicContact CG1-CG2 4.41Å; G216-T220 WeakPolarHBondContact O-CB 3.07Å; G216-T220 PolarHBondContact O-N 2.95Å; G216-T220 VanDerWaalsContact O-N 3.11Å; G216-T220 PolarHBondContact O-OG1 2.8Å; I217-T220 PolarHBondContact O-N 3.36Å; L218-T220 VanDerWaalsContact C-N 3.26Å; L218-T220 PolarHBondContact O-N 3.41Å; T220-C224 PolarHBondContact O-N 3.48Å; T220-C224 VanDerWaalsContact O-N 3.16Å; T220-R230 PolarHBondContact O-NH2 3.09Å
221	L	73.5	Confident	74.2	Confident	19 Å²	19	95.6 Å²	95.6	10%	0.099	46%	0.457	C	S	.	.	H	α-helix	trans	-71.7	-40.7	175	-73.6	167.3	0	0	0	111.9	I217 L218 R223 C224 R230	I217-L221 HydrophobicContact CG2-CD1 3.47Å; I217-L221 VanDerWaalsContact CG2-CD1 3.47Å; I217-L221 HydrophobicContact CG2-CG 4.16Å; I217-L221 WeakPolarHBondContact O-CB 3.45Å; I217-L221 VanDerWaalsContact O-CG 3.28Å; I217-L221 WeakPolarHBondContact O-CG 3.45Å; I217-L221 PolarHBondContact O-N 2.83Å; L218-L221 PolarHBondContact O-N 3.42Å; L218-L221 VanDerWaalsContact O-N 3.17Å; L221-R223 VanDerWaalsContact C-N 3.25Å; L221-R223 PolarHBondContact O-N 3.08Å; L221-C224 CarbonylContact O-C 3.08Å; L221-C224 PolarHBondContact O-N 3.41Å; L221-R230 HydrophobicContact CD2-CG 4.18Å
222	L	73.9	Confident	73.3	Confident	137 Å²	137	96.9 Å²	96.9	72%	0.717	45%	0.451	S	S	*	.	H	α-helix	trans	-63.3	-33.7	175.4	-69.7	171.1	0	0	0	111.8	L218	L218-L222 HydrophobicContact CD1-CG 4.42Å; L218-L222 HydrophobicContact CG-CD1 4.09Å; L218-L222 HydrophobicContact CG-CG 4.43Å; L218-L222 WeakPolarHBondContact O-CB 3.42Å; L218-L222 VanDerWaalsContact O-CG 3.28Å; L218-L222 WeakPolarHBondContact O-CG 3.3Å; L218-L222 PolarHBondContact O-N 3.4Å
223	R	73.9	Confident	72.2	Confident	226 Å²	226	93.9 Å²	93.9	85%	0.853	44%	0.441	S	S	*	.	H	α-helix	trans	-78.6	-27.8	178.3	-164.4	173.3	-178.1	-176.8	1	113.9	K219 L221	K219-R223 PolarHBondContact O-N 3.37Å; L221-R223 VanDerWaalsContact C-N 3.25Å; L221-R223 PolarHBondContact O-N 3.08Å
224	C	64.6	Low	71.4	Confident	63 Å²	63	94.4 Å²	94.4	43%	0.426	44%	0.444	S	S	.	.			trans	-125.4	94.1	-176.4	-58.9	0	0	0	0	110.7	T220 L221 N226 R230	T220-C224 PolarHBondContact O-N 3.48Å; T220-C224 VanDerWaalsContact O-N 3.16Å; L221-C224 CarbonylContact O-C 3.08Å; L221-C224 PolarHBondContact O-N 3.41Å; C224-N226 VanDerWaalsContact C-N 3.33Å; C224-N226 PolarHBondContact O-N 2.72Å; C224-R230 PolarHBondContact O-NH2 3.19Å
225	R	60.3	Low	71.2	Confident	227 Å²	227	99.3 Å²	99.3	86%	0.857	46%	0.462	S	S	*	.	T	Hydrogen-bonded Turn	trans	-73.4	-5.7	-168.5	-165.5	154.4	81.8	170.4	3.4	116.3
226	N	53.9	Low	70.7	Confident	142 Å²	142	97.6 Å²	97.6	76%	0.759	45%	0.447	S	S	*	.	T	Hydrogen-bonded Turn	trans	-108.8	10.7	-155.7	-74.8	-1.4	0	0	0	118.7	C224	C224-N226 VanDerWaalsContact C-N 3.33Å; C224-N226 PolarHBondContact O-N 2.72Å
227	E	64.6	Low	70.3	Confident	115 Å²	115	97.4 Å²	97.4	54%	0.537	44%	0.443	S	S	.	.			trans	-124.7	86.9	-174.1	-73.7	-65	161.7	0	0	114.9	K229 R230 H231	E227-K229 PolarHBondContact O-N 2.84Å; E227-K229 VanDerWaalsContact O-N 3.12Å; E227-R230 HydrophobicContact CB-CB 4.12Å; E227-R230 WeakPolarHBondContact O-CB 3.3Å; E227-R230 PolarHBondContact O-N 3.07Å; E227-H231 PolarHBondContact O-CD2 3.09Å; E227-H231 VanDerWaalsContact O-CD2 3.24Å
228	K	61.8	Low	70.2	Confident	173 Å²	173	101.3 Å²	101.3	75%	0.752	46%	0.46	S	S	*	.	H	α-helix	trans	-53.1	-32.4	177.2	-70.3	-178.8	-179.7	176.6	0	113.6	R230	K228-R230 VanDerWaalsContact C-N 3.34Å; K228-R230 PolarHBondContact O-N 3.3Å
229	K	59.1	Low	70.4	Confident	144 Å²	144	98.4 Å²	98.4	63%	0.626	45%	0.446	S	S	*	.	H	α-helix	trans	-69.8	-30.3	-178.7	-165.5	175.8	-179.3	179.8	0	112.6	E227	E227-K229 PolarHBondContact O-N 2.84Å; E227-K229 VanDerWaalsContact O-N 3.12Å
230	R	64.8	Low	70.5	Confident	52 Å²	52	90.7 Å²	90.7	20%	0.196	41%	0.413	C	S	.	.	H	α-helix	trans	-70.3	-41.6	179	-166.4	166.5	67.7	160.5	0.5	111.3	V130 T220 L221 C224 E227 K228 R232 A233 V234	V130-R230 HydrophobicContact CG1-CG 4.47Å; V130-R230 HydrophobicContact CG2-CG 3.81Å; T220-R230 PolarHBondContact O-NH2 3.09Å; L221-R230 HydrophobicContact CD2-CG 4.18Å; C224-R230 PolarHBondContact O-NH2 3.19Å; E227-R230 HydrophobicContact CB-CB 4.12Å; E227-R230 WeakPolarHBondContact O-CB 3.3Å; E227-R230 PolarHBondContact O-N 3.07Å; K228-R230 VanDerWaalsContact C-N 3.34Å; K228-R230 PolarHBondContact O-N 3.3Å; R230-R232 VanDerWaalsContact C-N 3.32Å; R230-R232 PolarHBondContact O-N 3.09Å; R230-A233 PolarHBondContact O-N 3.15Å; R230-V234 WeakPolarHBondContact O-CG2 3.44Å; R230-V234 PolarHBondContact O-N 2.82Å
231	H	67.6	Low	70.7	Confident	88 Å²	88	89.2 Å²	89.2	41%	0.407	40%	0.404	S	S	.	.	H	α-helix	trans	-60.4	-38.2	176.8	-66.9	-80.2	0	0	0	113	E227 V234 R235	E227-H231 PolarHBondContact O-CD2 3.09Å; E227-H231 VanDerWaalsContact O-CD2 3.24Å; H231-V234 PolarHBondContact O-N 2.03Å; H231-R235 WeakPolarHBondContact O-CB 3.4Å; H231-R235 PolarHBondContact O-N 3.21Å
232	R	69.1	Low	71.4	Confident	126 Å²	126	91.4 Å²	91.4	48%	0.475	42%	0.415	S	S	.	.	H	α-helix	trans	-65.4	-43.1	-178.6	-66.5	-177.5	-172.6	172.8	2.7	113	R230 R235 L236 E302	R230-R232 VanDerWaalsContact C-N 3.32Å; R230-R232 PolarHBondContact O-N 3.09Å; R232-R235 PolarHBondContact O-N 2.81Å; R232-L236 PolarHBondContact O-N 2.88Å; R232-L236 VanDerWaalsContact O-N 3.11Å; R232-E302 IonicContact CZ-OE1 3.87Å; R232-E302 IonicContact CZ-OE2 3.73Å; R232-E302 IonicContact NE-OE1 3.32Å; R232-E302 IonicContact NE-OE2 3.81Å; R232-E302 IonicContact NH1-OE1 3Å; R232-E302 IonicContact NH1-OE2 3.89Å; R232-E302 PolarHBondContact NH1-OE2 3.15Å
233	A	65.6	Low	72.3	Confident	34 Å²	34	86 Å²	86	28%	0.281	39%	0.387	S	S	.	.	H	α-helix	trans	-69.7	-37.8	179.6	0	0	0	0	0	112.2	R230 L236 I237	R230-A233 PolarHBondContact O-N 3.15Å; A233-L236 PolarHBondContact O-N 3.26Å; A233-I237 PolarHBondContact O-N 2.97Å
234	V	71.9	Confident	73	Confident	17 Å²	17	75.5 Å²	75.5	10%	0.103	35%	0.348	C	S	.	.	H	α-helix	trans	-64	-42.4	174.2	174.2	0	0	0	0	110.6	V130 Y214 I217 R230 H231 I237 F238	V130-V234 HydrophobicContact CG2-CG2 4.37Å; Y214-V234 HydrophobicContact CD1-CG1 4.28Å; Y214-V234 HydrophobicContact CE1-CG1 3.68Å; Y214-V234 PolarHBondContact OH-O 3.2Å; I217-V234 HydrophobicContact CG2-CG1 3.95Å; I217-V234 HydrophobicContact CG2-CG2 3.97Å; R230-V234 WeakPolarHBondContact O-CG2 3.44Å; R230-V234 PolarHBondContact O-N 2.82Å; H231-V234 PolarHBondContact O-N 2.03Å; V234-I237 PolarHBondContact O-N 2.87Å; V234-F238 VanDerWaalsContact O-CB 3.27Å; V234-F238 WeakPolarHBondContact O-CB 3.07Å; V234-F238 PolarHBondContact O-N 3.09Å
235	R	77.8	Confident	74.2	Confident	137 Å²	137	74.1 Å²	74.1	52%	0.517	34%	0.335	S	S	.	.	H	α-helix	trans	-59.7	-45.8	176.2	-171.3	177.5	71.9	-177.6	3.6	112.2	H231 R232 I237 F238 T239	H231-R235 WeakPolarHBondContact O-CB 3.4Å; H231-R235 PolarHBondContact O-N 3.21Å; R232-R235 PolarHBondContact O-N 2.81Å; R235-I237 PolarHBondContact O-N 3.32Å; R235-F238 PolarHBondContact O-N 3.18Å; R235-T239 PolarHBondContact O-N 3.06Å; R235-T239 PolarHBondContact O-OG1 2.94Å
236	L	75.7	Confident	75.8	Confident	34 Å²	34	68.5 Å²	68.5	18%	0.178	32%	0.321	C	S	.	.	H	α-helix	trans	-57.7	-50.1	179.5	178.3	65.2	0	0	0	112	R232 A233 F238 T239 I240 I296 Y297 V300	R232-L236 PolarHBondContact O-N 2.88Å; R232-L236 VanDerWaalsContact O-N 3.11Å; A233-L236 PolarHBondContact O-N 3.26Å; L236-F238 VanDerWaalsContact C-N 3.33Å; L236-F238 PolarHBondContact O-N 3.26Å; L236-T239 PolarHBondContact O-N 3.12Å; L236-I240 HydrophobicContact CD1-CD1 4.42Å; L236-I240 HydrophobicContact CG-CD1 4.14Å; L236-I240 WeakPolarHBondContact O-CG1 3.46Å; L236-I240 PolarHBondContact O-N 3.09Å; L236-I296 HydrophobicContact CD1-CG2 3.93Å; L236-Y297 HydrophobicContact CD1-CD1 4.32Å; L236-V300 HydrophobicContact CB-CG1 4.27Å; L236-V300 HydrophobicContact CD1-CB 3.74Å; L236-V300 HydrophobicContact CD1-CG1 3.73Å
237	I	75.3	Confident	77.7	Confident	10 Å²	10	63.7 Å²	63.7	5%	0.051	29%	0.293	C	S	.	.	H	α-helix	trans	-73	-30.6	-176.1	-73.3	166.6	0	0	0	111.7	L122 R126 A233 V234 R235 I240 M241	L122-I237 HydrophobicContact CB-CD1 4.31Å; R126-I237 HydrophobicContact CB-CD1 4.45Å; R126-I237 HydrophobicContact CG-CD1 3.12Å; R126-I237 HydrophobicContact CG-CG1 4.35Å; A233-I237 PolarHBondContact O-N 2.97Å; V234-I237 PolarHBondContact O-N 2.87Å; R235-I237 PolarHBondContact O-N 3.32Å; I237-I240 HydrophobicContact CG1-CD1 4.32Å; I237-I240 PolarHBondContact O-N 3.41Å; I237-M241 WeakPolarHBondContact O-CB 3.27Å; I237-M241 PolarHBondContact O-N 3.35Å
238	F	80.4	Confident	79.1	Confident	86 Å²	86	58.7 Å²	58.7	38%	0.377	27%	0.27	S	S	.	.	H	α-helix	trans	-64.3	-43	172.6	-174.3	-106.6	0	0	0	111	M210 Y214 V234 R235 L236 M241 I242	M210-F238 HydrophobicContact CE-CD2 3.35Å; M210-F238 HydrophobicContact CE-CE2 3.39Å; M210-F238 HydrophobicContact CE-CG 4.35Å; M210-F238 HydrophobicContact CE-CZ 4.41Å; Y214-F238 AromaticContact CD1-CD2 3.95Å; Y214-F238 HydrophobicContact CD1-CD2 3.95Å; Y214-F238 HydrophobicContact CE1-CB 3.8Å; Y214-F238 AromaticContact CE1-CD2 3.57Å; Y214-F238 HydrophobicContact CE1-CD2 3.57Å; Y214-F238 HydrophobicContact CE1-CG 4.09Å; Y214-F238 HydrophobicContact CE2-CD2 4.21Å; Y214-F238 HydrophobicContact CG-CD2 4.43Å; Y214-F238 AromaticContact CZ-CD2 3.73Å; Y214-F238 WeakPolarHBondContact OH-CA 3.19Å; Y214-F238 WeakPolarHBondContact OH-CB 3.47Å; Y214-F238 PolarHBondContact OH-N 2.81Å; V234-F238 VanDerWaalsContact O-CB 3.27Å; V234-F238 WeakPolarHBondContact O-CB 3.07Å; V234-F238 PolarHBondContact O-N 3.09Å; R235-F238 PolarHBondContact O-N 3.18Å; L236-F238 VanDerWaalsContact C-N 3.33Å; L236-F238 PolarHBondContact O-N 3.26Å; F238-M241 PolarHBondContact O-N 3.05Å; F238-I242 HydrophobicContact CD1-CD1 3.65Å; F238-I242 HydrophobicContact CE1-CD1 3.15Å; F238-I242 HydrophobicContact CE1-CG1 4.29Å; F238-I242 HydrophobicContact CE2-CD1 4.13Å; F238-I242 HydrophobicContact CG-CD1 4.33Å; F238-I242 HydrophobicContact CZ-CD1 3.44Å; F238-I242 VanDerWaalsContact CZ-CD1 3.44Å; F238-I242 HydrophobicContact CZ-CG1 4.36Å; F238-I242 WeakPolarHBondContact O-CG1 3.49Å; F238-I242 PolarHBondContact O-N 3.25Å
239	T	85.4	Confident	80.5	Confident	40 Å²	40	51.2 Å²	51.2	25%	0.245	24%	0.24	C	C	.	.	H	α-helix	trans	-62.3	-47	175.3	-58.2	0	0	0	0	111.9	R235 L236 M241 I242 V243 I296 V300	R235-T239 PolarHBondContact O-N 3.06Å; R235-T239 PolarHBondContact O-OG1 2.94Å; L236-T239 PolarHBondContact O-N 3.12Å; T239-M241 VanDerWaalsContact C-N 3.27Å; T239-M241 PolarHBondContact O-N 3.02Å; T239-I242 PolarHBondContact O-N 2.82Å; T239-V243 HydrophobicContact CG2-CG2 4.25Å; T239-V243 WeakPolarHBondContact O-CB 3.42Å; T239-V243 VanDerWaalsContact O-CG2 3.27Å; T239-V243 WeakPolarHBondContact O-CG2 3.34Å; T239-V243 PolarHBondContact O-N 3.3Å; T239-I296 HydrophobicContact CG2-CG2 4.17Å; T239-V300 HydrophobicContact CG2-CG2 4.26Å
240	I	83.9	Confident	82.3	Confident	3 Å²	3	46.3 Å²	46.3	2%	0.015	22%	0.223	C	C	.	.	H	α-helix	trans	-55.8	-45.5	177.6	-64	162.2	0	0	0	110.6	I119 L236 I237 V243 Y244 I296 Y297	I119-I240 HydrophobicContact CD1-CG2 4.15Å; I119-I240 HydrophobicContact CG1-CG2 4.16Å; L236-I240 HydrophobicContact CD1-CD1 4.42Å; L236-I240 HydrophobicContact CG-CD1 4.14Å; L236-I240 WeakPolarHBondContact O-CG1 3.46Å; L236-I240 PolarHBondContact O-N 3.09Å; I237-I240 HydrophobicContact CG1-CD1 4.32Å; I237-I240 PolarHBondContact O-N 3.41Å; I240-V243 PolarHBondContact O-N 2.89Å; I240-Y244 PolarHBondContact O-N 3.34Å; I240-I296 HydrophobicContact CG1-CD1 4.35Å; I240-I296 HydrophobicContact CG1-CG2 3.85Å; I240-Y297 HydrophobicContact CD1-CE1 3.64Å; I240-Y297 HydrophobicContact CG1-CE1 4.27Å
241	M	82.6	Confident	83.7	Confident	0 Å²	0	45 Å²	45	0%	0	22%	0.218	C	C	.	.	H	α-helix	trans	-67.1	-45.2	-178.6	-172.8	68.9	80.2	0	0	112.8	I119 T123 P206 M210 I237 F238 T239 V243 Y244 F245	I119-M241 HydrophobicContact CG2-CE 3.41Å; I119-M241 VanDerWaalsContact CG2-CE 3.41Å; I119-M241 HydrophobicContact CG2-SD 3.68Å; T123-M241 VanDerWaalsContact OG1-CE 3.3Å; T123-M241 WeakPolarHBondContact OG1-CE 3.5Å; P206-M241 HydrophobicContact CB-SD 4.17Å; M210-M241 HydrophobicContact CE-CB 4.05Å; M210-M241 HydrophobicContact CE-CG 3.8Å; M210-M241 HydrophobicContact CG-CG 4.33Å; M210-M241 HydrophobicContact SD-CG 3.72Å; I237-M241 WeakPolarHBondContact O-CB 3.27Å; I237-M241 PolarHBondContact O-N 3.35Å; F238-M241 PolarHBondContact O-N 3.05Å; T239-M241 VanDerWaalsContact C-N 3.27Å; T239-M241 PolarHBondContact O-N 3.02Å; M241-V243 VanDerWaalsContact C-N 3.32Å; M241-V243 PolarHBondContact O-N 3.48Å; M241-Y244 WeakPolarHBondContact O-CB 3.43Å; M241-Y244 PolarHBondContact O-N 2.84Å; M241-F245 HydrophobicContact CG-CD2 4.1Å; M241-F245 HydrophobicContact CG-CE2 3.45Å; M241-F245 VanDerWaalsContact CG-CE2 3.45Å; M241-F245 HydrophobicContact CG-CZ 4.15Å; M241-F245 WeakPolarHBondContact O-CD2 3.49Å; M241-F245 PolarHBondContact O-N 3.22Å; M241-F245 VanDerWaalsContact O-N 3.1Å; M241-F245 HydrophobicContact SD-CE2 3.73Å; M241-F245 HydrophobicContact SD-CZ 3.8Å
242	I	88.4	Confident	84.9	Confident	66 Å²	66	40.9 Å²	40.9	34%	0.338	20%	0.199	S	C	.	.	H	α-helix	trans	-61.4	-44.9	177.1	-71.9	177.9	0	0	0	110.6	M210 F238 T239 Y244 F245 L246	M210-I242 HydrophobicContact CE-CG1 4.24Å; F238-I242 HydrophobicContact CD1-CD1 3.65Å; F238-I242 HydrophobicContact CE1-CD1 3.15Å; F238-I242 HydrophobicContact CE1-CG1 4.29Å; F238-I242 HydrophobicContact CE2-CD1 4.13Å; F238-I242 HydrophobicContact CG-CD1 4.33Å; F238-I242 HydrophobicContact CZ-CD1 3.44Å; F238-I242 VanDerWaalsContact CZ-CD1 3.44Å; F238-I242 HydrophobicContact CZ-CG1 4.36Å; F238-I242 WeakPolarHBondContact O-CG1 3.49Å; F238-I242 PolarHBondContact O-N 3.25Å; T239-I242 PolarHBondContact O-N 2.82Å; I242-Y244 VanDerWaalsContact C-N 3.29Å; I242-Y244 PolarHBondContact O-N 2.82Å; I242-F245 PolarHBondContact O-N 3.1Å; I242-F245 VanDerWaalsContact O-N 3.14Å; I242-L246 HydrophobicContact CG2-CD1 3.89Å; I242-L246 HydrophobicContact CG2-CG 4.16Å; I242-L246 WeakPolarHBondContact O-CG 3.41Å; I242-L246 PolarHBondContact O-N 3.37Å
243	V	91.6	Very high	86	Confident	23 Å²	23	39.1 Å²	39.1	14%	0.139	20%	0.198	C	C	.	.	H	α-helix	trans	-62	-40.9	178.8	173.3	0	0	0	0	110.6	T239 I240 M241 F245 L246 F247 I292 I296	T239-V243 HydrophobicContact CG2-CG2 4.25Å; T239-V243 WeakPolarHBondContact O-CB 3.42Å; T239-V243 VanDerWaalsContact O-CG2 3.27Å; T239-V243 WeakPolarHBondContact O-CG2 3.34Å; T239-V243 PolarHBondContact O-N 3.3Å; I240-V243 PolarHBondContact O-N 2.89Å; M241-V243 VanDerWaalsContact C-N 3.32Å; M241-V243 PolarHBondContact O-N 3.48Å; V243-F245 VanDerWaalsContact C-N 3.33Å; V243-F245 PolarHBondContact O-N 3.26Å; V243-L246 PolarHBondContact O-N 3.29Å; V243-F247 HydrophobicContact CG1-CD2 3.87Å; V243-F247 HydrophobicContact CG1-CE2 3.83Å; V243-F247 WeakPolarHBondContact O-CD2 3.23Å; V243-F247 PolarHBondContact O-N 3.33Å; V243-F247 VanDerWaalsContact O-N 3.14Å; V243-I292 HydrophobicContact CG1-CB 4.5Å; V243-I292 HydrophobicContact CG1-CG2 3.7Å; V243-I296 HydrophobicContact CB-CD1 3.93Å; V243-I296 HydrophobicContact CG1-CD1 3.97Å; V243-I296 HydrophobicContact CG2-CD1 4Å
244	Y	89.1	Confident	87.4	Confident	5 Å²	5	38.2 Å²	38.2	2%	0.02	19%	0.19	C	C	.	.	H	α-helix	trans	-55.1	-47.7	172.7	174.7	-89.2	0	0	0	111.9	I116 I119 G202 I240 M241 I242 F247 W248 H289	I116-Y244 HydrophobicContact CB-CE2 4.12Å; I116-Y244 HydrophobicContact CD1-CD1 3.74Å; I116-Y244 HydrophobicContact CD1-CD2 4.22Å; I116-Y244 HydrophobicContact CD1-CE1 3.36Å; I116-Y244 HydrophobicContact CD1-CE2 3.87Å; I116-Y244 HydrophobicContact CD1-CG 4.17Å; I116-Y244 VanDerWaalsContact CD1-CZ 3.42Å; I116-Y244 HydrophobicContact CG1-CE1 4.02Å; I116-Y244 HydrophobicContact CG1-CE2 4.32Å; I119-Y244 HydrophobicContact CD1-CD2 3.98Å; I119-Y244 HydrophobicContact CD1-CG 4.28Å; G202-Y244 WeakPolarHBondContact O-CE1 3.46Å; G202-Y244 PolarHBondContact O-OH 3.45Å; G202-Y244 VanDerWaalsContact O-OH 3.04Å; I240-Y244 PolarHBondContact O-N 3.34Å; M241-Y244 WeakPolarHBondContact O-CB 3.43Å; M241-Y244 PolarHBondContact O-N 2.84Å; I242-Y244 VanDerWaalsContact C-N 3.29Å; I242-Y244 PolarHBondContact O-N 2.82Å; Y244-F247 PolarHBondContact O-N 2.88Å; Y244-W248 AromaticContact CD2-CD1 3.48Å; Y244-W248 VanDerWaalsContact CD2-CD1 3.48Å; Y244-W248 HydrophobicContact CD2-CG 4.31Å; Y244-W248 HydrophobicContact CE1-CB 4.24Å; Y244-W248 HydrophobicContact CE2-CB 4.28Å; Y244-W248 AromaticContact CE2-CD1 3.35Å; Y244-W248 AromaticContact CE2-CG 3.87Å; Y244-W248 HydrophobicContact CE2-CG 3.87Å; Y244-W248 AromaticContact CE2-NE1 3.91Å; Y244-W248 AromaticContact CZ-CD1 3.99Å; Y244-W248 WeakPolarHBondContact O-CB 3.49Å; Y244-W248 PolarHBondContact O-N 3.24Å; Y244-H289 WeakPolarHBondContact CA-NE2 3.25Å; Y244-H289 AromaticContact CD2-CE1 3.81Å; Y244-H289 AromaticContact CD2-NE2 3.94Å
245	F	89.8	Confident	88.3	Confident	34 Å²	34	38.2 Å²	38.2	15%	0.149	19%	0.189	C	C	.	.	H	α-helix	trans	-65.9	-40	178	-67.1	-53.8	0	0	0	113.5	L203 P206 P207 M210 M241 I242 V243 F247 A249	L203-F245 HydrophobicContact CD1-CD1 4.27Å; P206-F245 HydrophobicContact CB-CE1 4.06Å; P206-F245 HydrophobicContact CB-CZ 3.8Å; P207-F245 HydrophobicContact CB-CZ 4.02Å; P207-F245 HydrophobicContact CG-CD1 4.42Å; P207-F245 HydrophobicContact CG-CE1 3.48Å; P207-F245 VanDerWaalsContact CG-CE1 3.48Å; P207-F245 HydrophobicContact CG-CE2 4.19Å; P207-F245 HydrophobicContact CG-CZ 3.35Å; M210-F245 HydrophobicContact SD-CE2 3.97Å; M241-F245 HydrophobicContact CG-CD2 4.1Å; M241-F245 HydrophobicContact CG-CE2 3.45Å; M241-F245 VanDerWaalsContact CG-CE2 3.45Å; M241-F245 HydrophobicContact CG-CZ 4.15Å; M241-F245 WeakPolarHBondContact O-CD2 3.49Å; M241-F245 PolarHBondContact O-N 3.22Å; M241-F245 VanDerWaalsContact O-N 3.1Å; M241-F245 HydrophobicContact SD-CE2 3.73Å; M241-F245 HydrophobicContact SD-CZ 3.8Å; I242-F245 PolarHBondContact O-N 3.1Å; I242-F245 VanDerWaalsContact O-N 3.14Å; V243-F245 VanDerWaalsContact C-N 3.33Å; V243-F245 PolarHBondContact O-N 3.26Å; F245-F247 PolarHBondContact O-N 2.87Å; F245-A249 WeakPolarHBondContact O-CA 3.32Å; F245-A249 WeakPolarHBondContact O-CB 3.47Å; F245-A249 PolarHBondContact O-N 3.31Å
246	L	93.4	Very high	89	Confident	110 Å²	110	34.2 Å²	34.2	58%	0.576	18%	0.178	S	C	*	.	H	α-helix	trans	-59.1	-34	178	-71.4	174.2	0	0	0	112	I242 V243 P250	I242-L246 HydrophobicContact CG2-CD1 3.89Å; I242-L246 HydrophobicContact CG2-CG 4.16Å; I242-L246 WeakPolarHBondContact O-CG 3.41Å; I242-L246 PolarHBondContact O-N 3.37Å; V243-L246 PolarHBondContact O-N 3.29Å; L246-P250 WeakPolarHBondContact O-CD 3.12Å
247	F	93.6	Very high	89.7	Confident	40 Å²	40	34.9 Å²	34.9	18%	0.175	18%	0.181	C	C	.	.	H	α-helix	trans	-90	-39.7	-177.7	-77.2	-114.6	0	0	0	112.6	V243 Y244 F245 L285 T288 H289 I292	V243-F247 HydrophobicContact CG1-CD2 3.87Å; V243-F247 HydrophobicContact CG1-CE2 3.83Å; V243-F247 WeakPolarHBondContact O-CD2 3.23Å; V243-F247 PolarHBondContact O-N 3.33Å; V243-F247 VanDerWaalsContact O-N 3.14Å; Y244-F247 PolarHBondContact O-N 2.88Å; F245-F247 PolarHBondContact O-N 2.87Å; F247-L285 HydrophobicContact CD1-CD1 3.92Å; F247-L285 HydrophobicContact CD1-CG 4.24Å; F247-L285 WeakPolarHBondContact CD1-O 3.49Å; F247-L285 HydrophobicContact CE1-CD1 4.03Å; F247-L285 HydrophobicContact CG-CD1 4.46Å; F247-T288 WeakPolarHBondContact CD1-OG1 3.35Å; F247-T288 VanDerWaalsContact CE1-OG1 3.26Å; F247-T288 WeakPolarHBondContact CE1-OG1 3.28Å; F247-H289 HydrophobicContact CB-CB 3.93Å; F247-H289 HydrophobicContact CD1-CB 3.99Å; F247-H289 HydrophobicContact CG-CB 4.18Å; F247-I292 HydrophobicContact CE1-CD1 4.29Å; F247-I292 HydrophobicContact CE1-CG1 3.88Å; F247-I292 HydrophobicContact CZ-CD1 4.18Å; F247-I292 HydrophobicContact CZ-CG1 3.93Å
248	W	93.4	Very high	90.4	Very high	10 Å²	10	35.6 Å²	35.6	4%	0.038	19%	0.185	C	C	.	.	H	α-helix	trans	-99.7	-27.6	-172.9	-75.1	103.7	0	0	0	115.1	F79 F112 Y244 P250 Y251 N252 G286 H289	F79-W248 HydrophobicContact CE2-CH2 4.01Å; F79-W248 HydrophobicContact CE2-CZ2 4.18Å; F79-W248 AromaticContact CZ-CH2 3.95Å; F79-W248 HydrophobicContact CZ-CH2 3.95Å; F79-W248 HydrophobicContact CZ-CZ2 4.09Å; F112-W248 HydrophobicContact CD2-CD2 4.17Å; F112-W248 HydrophobicContact CD2-CE3 4.01Å; F112-W248 AromaticContact CD2-CH2 3.59Å; F112-W248 HydrophobicContact CD2-CH2 3.59Å; F112-W248 AromaticContact CD2-CZ2 3.78Å; F112-W248 HydrophobicContact CD2-CZ2 3.78Å; F112-W248 AromaticContact CD2-CZ3 3.71Å; F112-W248 HydrophobicContact CD2-CZ3 3.71Å; F112-W248 AromaticContact CE2-CD2 3.68Å; F112-W248 HydrophobicContact CE2-CD2 3.68Å; F112-W248 AromaticContact CE2-CE3 3.45Å; F112-W248 HydrophobicContact CE2-CE3 3.45Å; F112-W248 VanDerWaalsContact CE2-CE3 3.45Å; F112-W248 HydrophobicContact CE2-CG 4.37Å; F112-W248 AromaticContact CE2-CH2 3.94Å; F112-W248 HydrophobicContact CE2-CH2 3.94Å; F112-W248 HydrophobicContact CE2-CZ2 4.16Å; F112-W248 AromaticContact CE2-CZ3 3.58Å; F112-W248 HydrophobicContact CE2-CZ3 3.58Å; F112-W248 HydrophobicContact CZ-CE3 4.45Å; Y244-W248 AromaticContact CD2-CD1 3.48Å; Y244-W248 VanDerWaalsContact CD2-CD1 3.48Å; Y244-W248 HydrophobicContact CD2-CG 4.31Å; Y244-W248 HydrophobicContact CE1-CB 4.24Å; Y244-W248 HydrophobicContact CE2-CB 4.28Å; Y244-W248 AromaticContact CE2-CD1 3.35Å; Y244-W248 AromaticContact CE2-CG 3.87Å; Y244-W248 HydrophobicContact CE2-CG 3.87Å; Y244-W248 AromaticContact CE2-NE1 3.91Å; Y244-W248 AromaticContact CZ-CD1 3.99Å; Y244-W248 WeakPolarHBondContact O-CB 3.49Å; Y244-W248 PolarHBondContact O-N 3.24Å; W248-P250 VanDerWaalsContact C-CD 3.5Å; W248-Y251 HydrophobicContact CE3-CD1 4.16Å; W248-Y251 HydrophobicContact CZ3-CD1 4.19Å; W248-Y251 PolarHBondContact O-N 3.14Å; W248-N252 PolarHBondContact O-N 3.01Å; W248-N252 VanDerWaalsContact O-N 3.1Å; W248-N252 PolarHBondContact O-ND2 3.02Å; W248-G286 VanDerWaalsContact CZ2-O 3.25Å; W248-G286 WeakPolarHBondContact CZ2-O 3.25Å; W248-H289 AromaticContact CD1-CG 3.86Å; W248-H289 AromaticContact NE1-CG 3.49Å; W248-H289 AromaticContact NE1-ND1 3.53Å
249	A	93	Very high	90.7	Very high	17 Å²	17	31.9 Å²	31.9	14%	0.14	17%	0.169	C	C	.	.	H	α-helix	trans	-60.8	-41	179.4	0	0	0	0	0	113.1	L203 F245 Y251 N252 I253	L203-A249 HydrophobicContact CD1-CB 3.64Å; F245-A249 WeakPolarHBondContact O-CA 3.32Å; F245-A249 WeakPolarHBondContact O-CB 3.47Å; F245-A249 PolarHBondContact O-N 3.31Å; A249-Y251 VanDerWaalsContact C-N 3.3Å; A249-Y251 PolarHBondContact O-N 3.25Å; A249-N252 PolarHBondContact O-N 3.19Å; A249-I253 VanDerWaalsContact O-CG1 3.25Å; A249-I253 WeakPolarHBondContact O-CG1 3.3Å; A249-I253 PolarHBondContact O-N 3.46Å
250	P	95.3	Very high	90.9	Very high	41 Å²	41	32.5 Å²	32.5	27%	0.266	17%	0.169	S	C	.	.	H	α-helix	trans	-55.1	-45.6	176.1	-26.8	36.1	0	0	0	112.4	L246 W248 I253 V254 T282 L285	L246-P250 WeakPolarHBondContact O-CD 3.12Å; W248-P250 VanDerWaalsContact C-CD 3.5Å; P250-I253 PolarHBondContact O-N 3.27Å; P250-V254 VanDerWaalsContact O-CG2 3.31Å; P250-V254 WeakPolarHBondContact O-CG2 3.5Å; P250-V254 PolarHBondContact O-N 2.99Å; P250-T282 HydrophobicContact CB-CG2 3.6Å; P250-L285 HydrophobicContact CG-CD2 4.25Å
251	Y	93.8	Very high	90.9	Very high	24 Å²	24	33.9 Å²	33.9	9%	0.094	18%	0.175	C	C	.	.	H	α-helix	trans	-63.5	-47	178.1	173.8	-103.3	0	0	0	112.1	W248 A249 I253 V254 L255 M279 E283	W248-Y251 HydrophobicContact CE3-CD1 4.16Å; W248-Y251 HydrophobicContact CZ3-CD1 4.19Å; W248-Y251 PolarHBondContact O-N 3.14Å; A249-Y251 VanDerWaalsContact C-N 3.3Å; A249-Y251 PolarHBondContact O-N 3.25Å; Y251-I253 VanDerWaalsContact C-N 3.3Å; Y251-I253 PolarHBondContact O-N 2.91Å; Y251-V254 PolarHBondContact O-N 3.16Å; Y251-L255 HydrophobicContact CE1-CD2 4.29Å; Y251-L255 VanDerWaalsContact O-CB 3.3Å; Y251-L255 WeakPolarHBondContact O-CB 3.41Å; Y251-L255 PolarHBondContact O-N 3.41Å; Y251-M279 HydrophobicContact CE2-CG 4.28Å; Y251-E283 HydrophobicContact CD2-CB 3.69Å; Y251-E283 HydrophobicContact CD2-CG 4.35Å; Y251-E283 HydrophobicContact CE2-CB 3.72Å; Y251-E283 HydrophobicContact CE2-CG 4.04Å
252	N	93.2	Very high	90.9	Very high	1 Å²	1	41.5 Å²	41.5	1%	0.005	21%	0.211	C	C	.	.	H	α-helix	trans	-62.6	-37.5	-179.9	-77.7	-87.8	0	0	0	112.2	I198 V199 L203 W248 A249 L256	I198-N252 WeakPolarHBondContact CG2-OD1 3.18Å; I198-N252 PolarHBondContact O-OD1 3.4Å; V199-N252 HydrophobicContact CG2-CB 4.47Å; L203-N252 HydrophobicContact CB-CB 3.96Å; L203-N252 HydrophobicContact CD2-CB 3.76Å; L203-N252 HydrophobicContact CG-CB 4.35Å; W248-N252 PolarHBondContact O-N 3.01Å; W248-N252 VanDerWaalsContact O-N 3.1Å; W248-N252 PolarHBondContact O-ND2 3.02Å; A249-N252 PolarHBondContact O-N 3.19Å; N252-L256 PolarHBondContact O-N 3.1Å; N252-L256 VanDerWaalsContact O-N 3.1Å
253	I	93.5	Very high	90.7	Very high	89 Å²	89	46.5 Å²	46.5	46%	0.456	23%	0.23	S	C	.	.	H	α-helix	trans	-67	-47.4	175.7	-67	164.6	0	0	0	110.3	L203 A249 P250 Y251 L255 L256 L257	L203-I253 HydrophobicContact CD2-CG1 4.22Å; A249-I253 VanDerWaalsContact O-CG1 3.25Å; A249-I253 WeakPolarHBondContact O-CG1 3.3Å; A249-I253 PolarHBondContact O-N 3.46Å; P250-I253 PolarHBondContact O-N 3.27Å; Y251-I253 VanDerWaalsContact C-N 3.3Å; Y251-I253 PolarHBondContact O-N 2.91Å; I253-L255 VanDerWaalsContact C-N 3.33Å; I253-L255 PolarHBondContact O-N 3.43Å; I253-L256 WeakPolarHBondContact O-CB 3Å; I253-L256 PolarHBondContact O-N 3.48Å; I253-L257 HydrophobicContact CG2-CD1 4.2Å; I253-L257 WeakPolarHBondContact O-CG 3.36Å; I253-L257 PolarHBondContact O-N 2.93Å
254	V	93.3	Very high	90.3	Very high	16 Å²	16	50 Å²	50	10%	0.097	24%	0.244	C	C	.	.	H	α-helix	trans	-64.7	-38.3	178.9	175.3	0	0	0	0	111.3	P250 Y251 L256 L257 N258 A278 M279 T282	P250-V254 VanDerWaalsContact O-CG2 3.31Å; P250-V254 WeakPolarHBondContact O-CG2 3.5Å; P250-V254 PolarHBondContact O-N 2.99Å; Y251-V254 PolarHBondContact O-N 3.16Å; V254-L256 VanDerWaalsContact C-N 3.32Å; V254-L256 PolarHBondContact O-N 2.99Å; V254-L257 PolarHBondContact O-N 3.12Å; V254-N258 VanDerWaalsContact O-CB 3.28Å; V254-N258 WeakPolarHBondContact O-CB 3.36Å; V254-N258 PolarHBondContact O-N 3.49Å; V254-A278 HydrophobicContact CG1-CB 4.07Å; V254-A278 HydrophobicContact CG2-CB 4.19Å; V254-M279 HydrophobicContact CG1-CB 3.91Å; V254-T282 HydrophobicContact CG2-CG2 4.09Å
255	L	91.7	Very high	89.8	Confident	17 Å²	17	51.9 Å²	51.9	9%	0.089	27%	0.265	C	S	.	.	H	α-helix	trans	-60.8	-40.7	174.7	-177.8	67.9	0	0	0	111.9	T195 I198 Y251 I253 N258 T259	T195-L255 HydrophobicContact CG2-CD2 4.35Å; T195-L255 HydrophobicContact CG2-CG 4.02Å; I198-L255 HydrophobicContact CB-CD2 4.07Å; I198-L255 HydrophobicContact CD1-CD2 4.03Å; I198-L255 HydrophobicContact CG2-CD2 3.82Å; Y251-L255 HydrophobicContact CE1-CD2 4.29Å; Y251-L255 VanDerWaalsContact O-CB 3.3Å; Y251-L255 WeakPolarHBondContact O-CB 3.41Å; Y251-L255 PolarHBondContact O-N 3.41Å; I253-L255 VanDerWaalsContact C-N 3.33Å; I253-L255 PolarHBondContact O-N 3.43Å; L255-N258 PolarHBondContact O-N 3.22Å; L255-T259 WeakPolarHBondContact O-CB 3.47Å; L255-T259 PolarHBondContact O-N 3.27Å; L255-T259 PolarHBondContact O-OG1 2.89Å
256	L	92.7	Very high	89.3	Confident	53 Å²	53	52.6 Å²	52.6	28%	0.277	27%	0.27	S	S	.	.	H	α-helix	trans	-63.4	-48.9	174.7	-170.4	76	0	0	0	110.8	T195 V199 N252 I253 V254 N258 T259 F260	T195-L256 HydrophobicContact CG2-CD1 4.39Å; V199-L256 HydrophobicContact CG2-CB 4.45Å; V199-L256 HydrophobicContact CG2-CD1 4.4Å; N252-L256 PolarHBondContact O-N 3.1Å; N252-L256 VanDerWaalsContact O-N 3.1Å; I253-L256 WeakPolarHBondContact O-CB 3Å; I253-L256 PolarHBondContact O-N 3.48Å; V254-L256 VanDerWaalsContact C-N 3.32Å; V254-L256 PolarHBondContact O-N 2.99Å; L256-N258 VanDerWaalsContact C-N 3.32Å; L256-N258 PolarHBondContact O-N 3.42Å; L256-T259 PolarHBondContact O-N 3.08Å; L256-F260 HydrophobicContact CD1-CD2 3.72Å; L256-F260 HydrophobicContact CD1-CE2 3.64Å; L256-F260 HydrophobicContact CG-CD2 4.11Å; L256-F260 WeakPolarHBondContact O-CD2 3.24Å; L256-F260 PolarHBondContact O-N 2.86Å
257	L	90.9	Very high	88.4	Confident	47 Å²	47	52.4 Å²	52.4	25%	0.246	27%	0.27	C	S	.	.	H	α-helix	trans	-60.4	-40.8	177.3	-68.5	173.4	0	0	0	111.9	I253 V254 T259 F260 Q261 F264 L266 L275	I253-L257 HydrophobicContact CG2-CD1 4.2Å; I253-L257 WeakPolarHBondContact O-CG 3.36Å; I253-L257 PolarHBondContact O-N 2.93Å; V254-L257 PolarHBondContact O-N 3.12Å; L257-T259 VanDerWaalsContact C-N 3.31Å; L257-T259 PolarHBondContact O-N 2.89Å; L257-F260 CarbonylContact O-C 3.5Å; L257-Q261 WeakPolarHBondContact O-CA 3.48Å; L257-Q261 VanDerWaalsContact O-CG 3.25Å; L257-Q261 WeakPolarHBondContact O-CG 3.46Å; L257-Q261 PolarHBondContact O-N 2.87Å; L257-Q261 VanDerWaalsContact O-N 3.16Å; L257-F264 HydrophobicContact CD2-CD1 4.48Å; L257-F264 HydrophobicContact CD2-CD2 3.78Å; L257-F264 HydrophobicContact CD2-CE2 3.93Å; L257-F264 HydrophobicContact CD2-CG 4.08Å; L257-F264 HydrophobicContact CD2-CZ 4.34Å; L257-L266 HydrophobicContact CD2-CD1 4.38Å; L257-L275 HydrophobicContact CB-CD2 3.99Å
258	N	88.2	Confident	87.8	Confident	25 Å²	25	55 Å²	55	13%	0.134	29%	0.285	C	S	.	.	H	α-helix	trans	-68.3	-29.6	178.3	-170.6	47.8	0	0	0	112.9	V254 L255 L256 Q261	V254-N258 VanDerWaalsContact O-CB 3.28Å; V254-N258 WeakPolarHBondContact O-CB 3.36Å; V254-N258 PolarHBondContact O-N 3.49Å; L255-N258 PolarHBondContact O-N 3.22Å; L256-N258 VanDerWaalsContact C-N 3.32Å; L256-N258 PolarHBondContact O-N 3.42Å; N258-Q261 WeakPolarHBondContact O-CG 3.45Å; N258-Q261 PolarHBondContact OD1-NE2 3.16Å
259	T	88.1	Confident	87	Confident	8 Å²	8	57.8 Å²	57.8	5%	0.049	31%	0.306	C	S	.	.	H	α-helix	trans	-79.9	-39.2	178.4	-58.4	0	0	0	0	111.8	K191 N192 T195 L255 L256 L257	K191-T259 HydrophobicContact CD-CG2 4.43Å; K191-T259 HydrophobicContact CG-CG2 4.17Å; N192-T259 WeakPolarHBondContact OD1-CG2 3.42Å; T195-T259 WeakPolarHBondContact CB-OG1 3.36Å; T195-T259 HydrophobicContact CG2-CG2 4.14Å; T195-T259 WeakPolarHBondContact CG2-OG1 3.4Å; T195-T259 PolarHBondContact OG1-OG1 3.3Å; L255-T259 WeakPolarHBondContact O-CB 3.47Å; L255-T259 PolarHBondContact O-N 3.27Å; L255-T259 PolarHBondContact O-OG1 2.89Å; L256-T259 PolarHBondContact O-N 3.08Å; L257-T259 VanDerWaalsContact C-N 3.31Å; L257-T259 PolarHBondContact O-N 2.89Å
260	F	88.4	Confident	86.4	Confident	53 Å²	53	59.8 Å²	59.8	23%	0.232	32%	0.319	C	S	.	.	S	Bend	trans	-106.7	36.7	-176	-62.2	-73.6	0	0	0	112.6	L196 L256 L257 E262 F263 F264	L196-F260 HydrophobicContact CD2-CE2 4.34Å; L196-F260 HydrophobicContact CD2-CZ 4.39Å; L256-F260 HydrophobicContact CD1-CD2 3.72Å; L256-F260 HydrophobicContact CD1-CE2 3.64Å; L256-F260 HydrophobicContact CG-CD2 4.11Å; L256-F260 WeakPolarHBondContact O-CD2 3.24Å; L256-F260 PolarHBondContact O-N 2.86Å; L257-F260 CarbonylContact O-C 3.5Å; F260-E262 VanDerWaalsContact C-N 3.28Å; F260-E262 PolarHBondContact O-N 3.27Å; F260-F263 HydrophobicContact CB-CB 4.24Å; F260-F263 PolarHBondContact O-N 3.04Å; F260-F263 VanDerWaalsContact O-N 3.12Å; F260-F264 HydrophobicContact CB-CD2 4.04Å; F260-F264 HydrophobicContact CB-CE2 3.94Å; F260-F264 VanDerWaalsContact O-CD2 3.24Å; F260-F264 WeakPolarHBondContact O-CD2 3.25Å; F260-F264 PolarHBondContact O-N 2.94Å; F260-F264 VanDerWaalsContact O-N 3.16Å
261	Q	85	Confident	85.7	Confident	33 Å²	33	59.2 Å²	59.2	15%	0.154	32%	0.315	C	S	.	.	T	Hydrogen-bonded Turn	trans	-55.2	-41.6	-178.4	-73.3	176.8	-22.3	0	0	112.8	L257 N258 F263 F264 G265 L266 L275	L257-Q261 WeakPolarHBondContact O-CA 3.48Å; L257-Q261 VanDerWaalsContact O-CG 3.25Å; L257-Q261 WeakPolarHBondContact O-CG 3.46Å; L257-Q261 PolarHBondContact O-N 2.87Å; L257-Q261 VanDerWaalsContact O-N 3.16Å; N258-Q261 WeakPolarHBondContact O-CG 3.45Å; N258-Q261 PolarHBondContact OD1-NE2 3.16Å; Q261-F263 PolarHBondContact O-N 3.47Å; Q261-F264 PolarHBondContact O-N 3.38Å; Q261-G265 PolarHBondContact O-N 3.48Å; Q261-L266 HydrophobicContact CB-CB 4.34Å; Q261-L266 HydrophobicContact CG-CB 4.47Å; Q261-L266 PolarHBondContact O-N 3.36Å; Q261-L275 HydrophobicContact CG-CD1 3.79Å
262	E	82	Confident	84.9	Confident	160 Å²	160	59.4 Å²	59.4	75%	0.748	32%	0.32	S	S	*	.	T	Hydrogen-bonded Turn	trans	-62.6	-42.3	178.6	-67.5	178	-175.2	0	0	112	F260 F264 G265	F260-E262 VanDerWaalsContact C-N 3.28Å; F260-E262 PolarHBondContact O-N 3.27Å; E262-F264 VanDerWaalsContact C-N 3.32Å; E262-F264 PolarHBondContact O-N 2.99Å; E262-G265 PolarHBondContact O-N 3.36Å
263	F	84.8	Confident	84.3	Confident	170 Å²	170	59.7 Å²	59.7	75%	0.746	32%	0.322	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.9	-35.5	179.5	-175.1	-96.7	0	0	0	112.3	F260 Q261	F260-F263 HydrophobicContact CB-CB 4.24Å; F260-F263 PolarHBondContact O-N 3.04Å; F260-F263 VanDerWaalsContact O-N 3.12Å; Q261-F263 PolarHBondContact O-N 3.47Å
264	F	82.9	Confident	83.9	Confident	97 Å²	97	64 Å²	64	43%	0.425	33%	0.332	S	S	.	.	T	Hydrogen-bonded Turn	trans	-89.3	2.2	178.1	-68.3	-67.7	0	0	0	114	L257 F260 Q261 E262 L266	L257-F264 HydrophobicContact CD2-CD1 4.48Å; L257-F264 HydrophobicContact CD2-CD2 3.78Å; L257-F264 HydrophobicContact CD2-CE2 3.93Å; L257-F264 HydrophobicContact CD2-CG 4.08Å; L257-F264 HydrophobicContact CD2-CZ 4.34Å; F260-F264 HydrophobicContact CB-CD2 4.04Å; F260-F264 HydrophobicContact CB-CE2 3.94Å; F260-F264 VanDerWaalsContact O-CD2 3.24Å; F260-F264 WeakPolarHBondContact O-CD2 3.25Å; F260-F264 PolarHBondContact O-N 2.94Å; F260-F264 VanDerWaalsContact O-N 3.16Å; Q261-F264 PolarHBondContact O-N 3.38Å; E262-F264 VanDerWaalsContact C-N 3.32Å; E262-F264 PolarHBondContact O-N 2.99Å; F264-L266 VanDerWaalsContact C-N 3.29Å; F264-L266 HydrophobicContact CB-CD1 3.98Å; F264-L266 HydrophobicContact CB-CG 4.05Å; F264-L266 PolarHBondContact O-N 3.36Å
265	G	77.8	Confident	83.5	Confident	45 Å²	45	64 Å²	64	46%	0.464	33%	0.332	S	S	.	.	T	Hydrogen-bonded Turn	trans	66.4	27.8	-177.6	0	0	0	0	0	114.1	Q261 E262	Q261-G265 PolarHBondContact O-N 3.48Å; E262-G265 PolarHBondContact O-N 3.36Å
266	L	79.4	Confident	83	Confident	49 Å²	49	65.6 Å²	65.6	26%	0.257	34%	0.34	S	S	.	.			trans	-100.8	16.3	-177.9	-63.1	174.7	0	0	0	113.3	L257 Q261 F264 N268 S271 L275	L257-L266 HydrophobicContact CD2-CD1 4.38Å; Q261-L266 HydrophobicContact CB-CB 4.34Å; Q261-L266 HydrophobicContact CG-CB 4.47Å; Q261-L266 PolarHBondContact O-N 3.36Å; F264-L266 VanDerWaalsContact C-N 3.29Å; F264-L266 HydrophobicContact CB-CD1 3.98Å; F264-L266 HydrophobicContact CB-CG 4.05Å; F264-L266 PolarHBondContact O-N 3.36Å; L266-N268 PolarHBondContact O-N 2.89Å; L266-S271 WeakPolarHBondContact O-CB 3.41Å; L266-L275 HydrophobicContact CB-CD1 4.09Å; L266-L275 HydrophobicContact CD1-CD1 4.05Å
267	N	75.3	Confident	82.6	Confident	106 Å²	106	65.9 Å²	65.9	57%	0.567	34%	0.34	S	S	*	.			trans	-74.7	3.6	-177.2	65.8	-16.1	0	0	0	114.8
268	N	81.9	Confident	82.5	Confident	94 Å²	94	65.4 Å²	65.4	50%	0.503	34%	0.343	S	S	.	.	S	Bend	trans	-72.5	143.7	174.7	-64	-34.3	0	0	0	111.2	L266 S270 S271 S272	L266-N268 PolarHBondContact O-N 2.89Å; N268-S270 VanDerWaalsContact C-N 3.31Å; N268-S270 PolarHBondContact O-N 3.47Å; N268-S271 PolarHBondContact O-N 2.93Å; N268-S272 PolarHBondContact O-N 2.89Å
269	C	76.3	Confident	82.5	Confident	69 Å²	69	66.4 Å²	66.4	47%	0.466	35%	0.347	S	S	.	.	H	α-helix	trans	-54	-44.7	-178.3	-173.3	0	0	0	0	112.7	S271 S272 N273	C269-S271 PolarHBondContact O-N 2.8Å; C269-S272 PolarHBondContact O-N 2.94Å; C269-N273 WeakPolarHBondContact O-CB 3.19Å; C269-N273 PolarHBondContact O-N 3.38Å
270	S	79.6	Confident	82.5	Confident	59 Å²	59	69.3 Å²	69.3	41%	0.413	36%	0.36	S	S	.	.	H	α-helix	trans	-64.9	-39.3	177.9	57.7	0	0	0	0	113	N268 R274	N268-S270 VanDerWaalsContact C-N 3.31Å; N268-S270 PolarHBondContact O-N 3.47Å; S270-R274 WeakPolarHBondContact O-CG 3.42Å; S270-R274 PolarHBondContact O-N 3.43Å; S270-R274 VanDerWaalsContact O-N 3.14Å
271	S	80.3	Confident	82.5	Confident	29 Å²	29	71.5 Å²	71.5	20%	0.203	38%	0.378	C	S	.	.	H	α-helix	trans	-68.4	-43.4	175.9	-65.1	0	0	0	0	111.8	L266 N268 C269 N273 R274 L275	L266-S271 WeakPolarHBondContact O-CB 3.41Å; N268-S271 PolarHBondContact O-N 2.93Å; C269-S271 PolarHBondContact O-N 2.8Å; S271-N273 VanDerWaalsContact C-N 3.33Å; S271-N273 PolarHBondContact O-N 2.91Å; S271-R274 PolarHBondContact O-N 2.96Å; S271-L275 WeakPolarHBondContact O-CG 3.49Å; S271-L275 PolarHBondContact O-N 3.02Å
272	S	78.8	Confident	82.9	Confident	28 Å²	28	70.8 Å²	70.8	20%	0.196	38%	0.376	C	S	.	.	H	α-helix	trans	-61.8	-41	175.3	-174.4	0	0	0	0	111.6	N268 C269 R274 L275 D276	N268-S272 PolarHBondContact O-N 2.89Å; C269-S272 PolarHBondContact O-N 2.94Å; S272-R274 PolarHBondContact O-N 3.23Å; S272-L275 PolarHBondContact O-N 2.84Å; S272-D276 PolarHBondContact O-N 3.47Å
273	N	80.3	Confident	83.3	Confident	6 Å²	6	65.2 Å²	65.2	3%	0.032	35%	0.35	C	S	.	.	H	α-helix	trans	-65.8	-38.6	178.3	-166.1	28.4	0	0	0	112.2	Q21 K22 C269 S271 L275 D276 Q277	Q21-N273 VanDerWaalsContact CD-ND2 3.31Å; Q21-N273 WeakPolarHBondContact CG-ND2 3.3Å; Q21-N273 PolarHBondContact OE1-ND2 3.45Å; K22-N273 WeakPolarHBondContact CG-OD1 3.42Å; C269-N273 WeakPolarHBondContact O-CB 3.19Å; C269-N273 PolarHBondContact O-N 3.38Å; S271-N273 VanDerWaalsContact C-N 3.33Å; S271-N273 PolarHBondContact O-N 2.91Å; N273-L275 VanDerWaalsContact C-N 3.35Å; N273-D276 PolarHBondContact O-N 3.3Å; N273-Q277 WeakPolarHBondContact O-CG 3.2Å; N273-Q277 PolarHBondContact O-N 3.01Å; N273-Q277 VanDerWaalsContact O-N 3.14Å
274	R	84.5	Confident	83.7	Confident	179 Å²	179	57.8 Å²	57.8	68%	0.675	32%	0.318	S	S	*	.	H	α-helix	trans	-65.8	-37.2	172.9	-71.1	176.1	-174.5	-166.4	2.5	112.1	S270 S271 S272 Q277 A278	S270-R274 WeakPolarHBondContact O-CG 3.42Å; S270-R274 PolarHBondContact O-N 3.43Å; S270-R274 VanDerWaalsContact O-N 3.14Å; S271-R274 PolarHBondContact O-N 2.96Å; S272-R274 PolarHBondContact O-N 3.23Å; R274-Q277 PolarHBondContact O-N 3.31Å; R274-A278 WeakPolarHBondContact O-CB 3.34Å; R274-A278 PolarHBondContact O-N 3.5Å
275	L	84.8	Confident	84.2	Confident	17 Å²	17	56.3 Å²	56.3	9%	0.089	31%	0.314	C	S	.	.	H	α-helix	trans	-66.5	-41.9	175.1	-77.8	170.1	0	0	0	112	L257 Q261 L266 S271 S272 N273 Q277 A278 M279	L257-L275 HydrophobicContact CB-CD2 3.99Å; Q261-L275 HydrophobicContact CG-CD1 3.79Å; L266-L275 HydrophobicContact CB-CD1 4.09Å; L266-L275 HydrophobicContact CD1-CD1 4.05Å; S271-L275 WeakPolarHBondContact O-CG 3.49Å; S271-L275 PolarHBondContact O-N 3.02Å; S272-L275 PolarHBondContact O-N 2.84Å; N273-L275 VanDerWaalsContact C-N 3.35Å; L275-Q277 VanDerWaalsContact C-N 3.31Å; L275-Q277 PolarHBondContact O-N 3.08Å; L275-A278 PolarHBondContact O-N 3.09Å; L275-M279 WeakPolarHBondContact O-CB 3.38Å; L275-M279 PolarHBondContact O-N 3.22Å
276	D	81.9	Confident	84.9	Confident	50 Å²	50	54.1 Å²	54.1	27%	0.267	29%	0.292	S	S	.	.	H	α-helix	trans	-58.3	-44.7	174.8	-71	-18.1	0	0	0	110.8	K22 S272 N273 M279 Q280	K22-D276 IonicContact NZ-OD2 2.88Å; K22-D276 PolarHBondContact NZ-OD2 3.15Å; S272-D276 PolarHBondContact O-N 3.47Å; N273-D276 PolarHBondContact O-N 3.3Å; D276-M279 PolarHBondContact O-N 3.45Å; D276-Q280 PolarHBondContact O-N 2.97Å; D276-Q280 VanDerWaalsContact O-N 3.08Å
277	Q	84.1	Confident	85.4	Confident	60 Å²	60	52 Å²	52	28%	0.28	28%	0.281	S	S	.	.	H	α-helix	trans	-62.7	-47.3	175.1	-71.1	172.7	23.6	0	0	112.3	V25 N273 R274 L275 M279 Q280 V281	V25-Q277 HydrophobicContact CB-CG 4.38Å; V25-Q277 HydrophobicContact CG1-CG 3.85Å; V25-Q277 HydrophobicContact CG2-CG 3.63Å; V25-Q277 VanDerWaalsContact CG2-NE2 3.26Å; N273-Q277 WeakPolarHBondContact O-CG 3.2Å; N273-Q277 PolarHBondContact O-N 3.01Å; N273-Q277 VanDerWaalsContact O-N 3.14Å; R274-Q277 PolarHBondContact O-N 3.31Å; L275-Q277 VanDerWaalsContact C-N 3.31Å; L275-Q277 PolarHBondContact O-N 3.08Å; Q277-M279 VanDerWaalsContact C-N 3.26Å; Q277-M279 PolarHBondContact O-N 2.86Å; Q277-Q280 PolarHBondContact O-N 3.36Å; Q277-V281 WeakPolarHBondContact O-CG2 3.3Å; Q277-V281 PolarHBondContact O-N 3.03Å
278	A	88.6	Confident	86.2	Confident	36 Å²	36	48 Å²	48	30%	0.298	26%	0.26	S	S	.	.	H	α-helix	trans	-61	-38.2	177.7	0	0	0	0	0	111.3	V254 R274 L275 V281 T282	V254-A278 HydrophobicContact CG1-CB 4.07Å; V254-A278 HydrophobicContact CG2-CB 4.19Å; R274-A278 WeakPolarHBondContact O-CB 3.34Å; R274-A278 PolarHBondContact O-N 3.5Å; L275-A278 PolarHBondContact O-N 3.09Å; A278-V281 PolarHBondContact O-N 2.7Å; A278-T282 WeakPolarHBondContact O-CB 3.35Å; A278-T282 VanDerWaalsContact O-CG2 3.27Å; A278-T282 WeakPolarHBondContact O-CG2 3.3Å; A278-T282 PolarHBondContact O-N 3.45Å; A278-T282 PolarHBondContact O-OG1 3.39Å
279	M	88.4	Confident	86.8	Confident	47 Å²	47	43.9 Å²	43.9	23%	0.232	24%	0.238	C	C	.	.	H	α-helix	trans	-63.4	-47.1	178.2	-169.3	168.3	69.3	0	0	110.5	Y251 V254 L275 D276 Q277 V281 T282 E283	Y251-M279 HydrophobicContact CE2-CG 4.28Å; V254-M279 HydrophobicContact CG1-CB 3.91Å; L275-M279 WeakPolarHBondContact O-CB 3.38Å; L275-M279 PolarHBondContact O-N 3.22Å; D276-M279 PolarHBondContact O-N 3.45Å; Q277-M279 VanDerWaalsContact C-N 3.26Å; Q277-M279 PolarHBondContact O-N 2.86Å; M279-V281 PolarHBondContact O-N 3.12Å; M279-T282 PolarHBondContact O-N 2.95Å; M279-T282 PolarHBondContact O-OG1 3.4Å; M279-E283 WeakPolarHBondContact O-CB 3.35Å; M279-E283 PolarHBondContact O-N 3.41Å
280	Q	86.8	Confident	87.4	Confident	68 Å²	68	40.7 Å²	40.7	32%	0.318	22%	0.217	S	C	.	.	H	α-helix	trans	-60	-46.5	177.2	-171.8	66.1	51.6	0	0	112.3	D276 Q277 T284	D276-Q280 PolarHBondContact O-N 2.97Å; D276-Q280 VanDerWaalsContact O-N 3.08Å; Q277-Q280 PolarHBondContact O-N 3.36Å; Q280-T284 WeakPolarHBondContact O-CB 3.33Å; Q280-T284 PolarHBondContact O-N 2.67Å; Q280-T284 PolarHBondContact O-OG1 2.81Å
281	V	90	Very high	87.9	Confident	100 Å²	100	38.5 Å²	38.5	61%	0.606	20%	0.201	S	C	*	.	H	α-helix	trans	-66.3	-45.4	-178.7	172.8	0	0	0	0	111.1	Q277 A278 M279 T284 L285	Q277-V281 WeakPolarHBondContact O-CG2 3.3Å; Q277-V281 PolarHBondContact O-N 3.03Å; A278-V281 PolarHBondContact O-N 2.7Å; M279-V281 PolarHBondContact O-N 3.12Å; V281-T284 WeakPolarHBondContact O-CB 3.29Å; V281-T284 PolarHBondContact O-N 3.35Å; V281-L285 PolarHBondContact O-N 2.91Å
282	T	92.9	Very high	88.4	Confident	18 Å²	18	38.8 Å²	38.8	11%	0.11	20%	0.2	C	C	.	.	H	α-helix	trans	-71.7	-33.5	-178.8	55.2	0	0	0	0	112.6	P250 V254 A278 M279 L285 G286	P250-T282 HydrophobicContact CB-CG2 3.6Å; V254-T282 HydrophobicContact CG2-CG2 4.09Å; A278-T282 WeakPolarHBondContact O-CB 3.35Å; A278-T282 VanDerWaalsContact O-CG2 3.27Å; A278-T282 WeakPolarHBondContact O-CG2 3.3Å; A278-T282 PolarHBondContact O-N 3.45Å; A278-T282 PolarHBondContact O-OG1 3.39Å; M279-T282 PolarHBondContact O-N 2.95Å; M279-T282 PolarHBondContact O-OG1 3.4Å; T282-L285 WeakPolarHBondContact O-CB 3.37Å; T282-L285 PolarHBondContact O-N 2.81Å; T282-G286 PolarHBondContact O-N 3.42Å
283	E	91.1	Very high	88.8	Confident	43 Å²	43	37.5 Å²	37.5	20%	0.201	19%	0.191	C	C	.	.	H	α-helix	trans	-64.1	-44.8	170.9	-176.3	174.2	-161.6	0	0	111.1	Y251 M279 L285 G286 M287	Y251-E283 HydrophobicContact CD2-CB 3.69Å; Y251-E283 HydrophobicContact CD2-CG 4.35Å; Y251-E283 HydrophobicContact CE2-CB 3.72Å; Y251-E283 HydrophobicContact CE2-CG 4.04Å; M279-E283 WeakPolarHBondContact O-CB 3.35Å; M279-E283 PolarHBondContact O-N 3.41Å; E283-L285 VanDerWaalsContact C-N 3.3Å; E283-L285 PolarHBondContact O-N 2.82Å; E283-G286 CarbonylContact O-C 3.51Å; E283-G286 WeakPolarHBondContact O-CA 3.45Å; E283-G286 PolarHBondContact O-N 3.43Å; E283-G286 VanDerWaalsContact O-N 3.12Å; E283-M287 HydrophobicContact CG-CE 4.12Å; E283-M287 HydrophobicContact CG-CG 4.48Å; E283-M287 VanDerWaalsContact O-CG 3.27Å; E283-M287 WeakPolarHBondContact O-CG 3.26Å; E283-M287 PolarHBondContact O-N 3.35Å
284	T	91.3	Very high	89.1	Confident	13 Å²	13	37.7 Å²	37.7	8%	0.08	19%	0.193	C	C	.	.	H	α-helix	trans	-58.2	-44.5	175.8	-57.2	0	0	0	0	110.8	L33 L36 Y37 Q280 V281 M287 T288	L33-T284 HydrophobicContact CD2-CG2 3.48Å; L33-T284 VanDerWaalsContact CD2-CG2 3.48Å; L33-T284 WeakPolarHBondContact CD2-OG1 3.19Å; L36-T284 HydrophobicContact CD2-CG2 3.52Å; Y37-T284 HydrophobicContact CE1-CG2 3.88Å; Q280-T284 WeakPolarHBondContact O-CB 3.33Å; Q280-T284 PolarHBondContact O-N 2.67Å; Q280-T284 PolarHBondContact O-OG1 2.81Å; V281-T284 WeakPolarHBondContact O-CB 3.29Å; V281-T284 PolarHBondContact O-N 3.35Å; T284-M287 WeakPolarHBondContact O-CB 3.44Å; T284-M287 PolarHBondContact O-N 3.25Å; T284-T288 VanDerWaalsContact O-CG2 3.29Å; T284-T288 WeakPolarHBondContact O-CG2 3.33Å; T284-T288 PolarHBondContact O-N 3.11Å; T284-T288 VanDerWaalsContact O-N 3.15Å
285	L	93.6	Very high	89.2	Confident	66 Å²	66	32.9 Å²	32.9	35%	0.346	18%	0.18	S	C	.	.	H	α-helix	trans	-58.1	-50.3	173.8	-179.2	65.5	0	0	0	110.7	F247 P250 V281 T282 E283 M287 T288	F247-L285 HydrophobicContact CD1-CD1 3.92Å; F247-L285 HydrophobicContact CD1-CG 4.24Å; F247-L285 WeakPolarHBondContact CD1-O 3.49Å; F247-L285 HydrophobicContact CE1-CD1 4.03Å; F247-L285 HydrophobicContact CG-CD1 4.46Å; P250-L285 HydrophobicContact CG-CD2 4.25Å; V281-L285 PolarHBondContact O-N 2.91Å; T282-L285 WeakPolarHBondContact O-CB 3.37Å; T282-L285 PolarHBondContact O-N 2.81Å; E283-L285 VanDerWaalsContact C-N 3.3Å; E283-L285 PolarHBondContact O-N 2.82Å; L285-M287 VanDerWaalsContact C-N 3.3Å; L285-M287 PolarHBondContact O-N 3.07Å; L285-T288 PolarHBondContact O-N 2.93Å; L285-T288 VanDerWaalsContact O-N 3.09Å; L285-T288 PolarHBondContact O-OG1 3.39Å
286	G	92.9	Very high	89.2	Confident	0 Å²	0	32.6 Å²	32.6	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-55.3	-42.9	175.1	0	0	0	0	0	112.9	W248 T282 E283 T288 H289	W248-G286 VanDerWaalsContact CZ2-O 3.25Å; W248-G286 WeakPolarHBondContact CZ2-O 3.25Å; T282-G286 PolarHBondContact O-N 3.42Å; E283-G286 CarbonylContact O-C 3.51Å; E283-G286 WeakPolarHBondContact O-CA 3.45Å; E283-G286 PolarHBondContact O-N 3.43Å; E283-G286 VanDerWaalsContact O-N 3.12Å; G286-T288 VanDerWaalsContact C-N 3.28Å; G286-T288 PolarHBondContact O-N 3.08Å; G286-H289 WeakPolarHBondContact O-CB 3.27Å; G286-H289 PolarHBondContact O-N 3.31Å
287	M	90.3	Very high	89.1	Confident	4 Å²	4	30.8 Å²	30.8	2%	0.02	17%	0.167	C	C	.	.	H	α-helix	trans	-60.3	-36.4	177.5	-65.9	-132	-171.9	0	0	112.5	Y37 F79 W86 Y108 E283 T284 L285 H289 C290	Y37-M287 HydrophobicContact CE1-CB 4.05Å; Y37-M287 HydrophobicContact CE1-CG 4.4Å; Y37-M287 HydrophobicContact CE1-SD 4.28Å; Y37-M287 HydrophobicContact CE2-SD 4.23Å; F79-M287 HydrophobicContact CE1-CB 4.16Å; F79-M287 HydrophobicContact CE1-CG 4.25Å; F79-M287 HydrophobicContact CE1-SD 4.35Å; F79-M287 HydrophobicContact CZ-CB 4.4Å; F79-M287 HydrophobicContact CZ-CG 4.09Å; F79-M287 HydrophobicContact CZ-SD 4.33Å; W86-M287 HydrophobicContact CG-CE 4.33Å; Y108-M287 HydrophobicContact CD2-CE 4.48Å; Y108-M287 HydrophobicContact CE2-CE 3.77Å; Y108-M287 HydrophobicContact CE2-SD 4.42Å; E283-M287 HydrophobicContact CG-CE 4.12Å; E283-M287 HydrophobicContact CG-CG 4.48Å; E283-M287 VanDerWaalsContact O-CG 3.27Å; E283-M287 WeakPolarHBondContact O-CG 3.26Å; E283-M287 PolarHBondContact O-N 3.35Å; T284-M287 WeakPolarHBondContact O-CB 3.44Å; T284-M287 PolarHBondContact O-N 3.25Å; L285-M287 VanDerWaalsContact C-N 3.3Å; L285-M287 PolarHBondContact O-N 3.07Å; M287-H289 PolarHBondContact O-N 3.14Å; M287-C290 PolarHBondContact O-SG 2.82Å
288	T	92.9	Very high	88.7	Confident	22 Å²	22	29.4 Å²	29.4	14%	0.135	17%	0.166	C	C	.	.	H	α-helix	trans	-67.6	-18.6	178.4	69.1	0	0	0	0	113.5	V40 F247 T284 L285 G286 C290 C291	V40-T288 HydrophobicContact CG2-CG2 3.77Å; F247-T288 WeakPolarHBondContact CD1-OG1 3.35Å; F247-T288 VanDerWaalsContact CE1-OG1 3.26Å; F247-T288 WeakPolarHBondContact CE1-OG1 3.28Å; T284-T288 VanDerWaalsContact O-CG2 3.29Å; T284-T288 WeakPolarHBondContact O-CG2 3.33Å; T284-T288 PolarHBondContact O-N 3.11Å; T284-T288 VanDerWaalsContact O-N 3.15Å; L285-T288 PolarHBondContact O-N 2.93Å; L285-T288 VanDerWaalsContact O-N 3.09Å; L285-T288 PolarHBondContact O-OG1 3.39Å; G286-T288 VanDerWaalsContact C-N 3.28Å; G286-T288 PolarHBondContact O-N 3.08Å; T288-C290 PolarHBondContact O-N 3.4Å; T288-C291 PolarHBondContact O-N 3.33Å; T288-C291 PolarHBondContact O-SG 2.74Å
289	H	93	Very high	88	Confident	7 Å²	7	35.8 Å²	35.8	3%	0.032	19%	0.188	C	C	.	.	G	3₁₀ helix	trans	-56.7	-34.6	-179.2	177	-95.1	0	0	0	113.4	Y244 F247 W248 G286 M287 C291 I292	Y244-H289 WeakPolarHBondContact CA-NE2 3.25Å; Y244-H289 AromaticContact CD2-CE1 3.81Å; Y244-H289 AromaticContact CD2-NE2 3.94Å; F247-H289 HydrophobicContact CB-CB 3.93Å; F247-H289 HydrophobicContact CD1-CB 3.99Å; F247-H289 HydrophobicContact CG-CB 4.18Å; W248-H289 AromaticContact CD1-CG 3.86Å; W248-H289 AromaticContact NE1-CG 3.49Å; W248-H289 AromaticContact NE1-ND1 3.53Å; G286-H289 WeakPolarHBondContact O-CB 3.27Å; G286-H289 PolarHBondContact O-N 3.31Å; M287-H289 PolarHBondContact O-N 3.14Å; H289-C291 PolarHBondContact O-N 3.5Å; H289-C291 VanDerWaalsContact O-N 3.09Å; H289-I292 WeakPolarHBondContact O-CB 3.33Å; H289-I292 PolarHBondContact O-N 3.28Å
290	C	90.1	Very high	87.1	Confident	3 Å²	3	35.2 Å²	35.2	2%	0.02	19%	0.187	C	C	.	.	G	3₁₀ helix	trans	-61.4	-20.6	-175.3	64.5	0	0	0	0	114.3	V40 N48 D76 F79 L80 M287 T288	V40-C290 VanDerWaalsContact CG1-SG 3.59Å; N48-C290 PolarHBondContact ND2-O 2.88Å; D76-C290 HydrophobicContact CB-CB 4.47Å; F79-C290 HydrophobicContact CD1-CB 3.93Å; L80-C290 HydrophobicContact CD2-CB 4.48Å; L80-C290 WeakPolarHBondContact CD2-SG 3.35Å; L80-C290 HydrophobicContact CG-CB 4.21Å; M287-C290 PolarHBondContact O-SG 2.82Å; T288-C290 PolarHBondContact O-N 3.4Å
291	C	90.3	Very high	86.2	Confident	13 Å²	13	32.4 Å²	32.4	9%	0.088	18%	0.176	C	C	.	.	G	3₁₀ helix	trans	-94.7	-7.7	175.1	73.2	0	0	0	0	113.9	V40 F43 T288 H289	V40-C291 HydrophobicContact CG1-CB 4.49Å; F43-C291 HydrophobicContact CB-CB 4.41Å; T288-C291 PolarHBondContact O-N 3.33Å; T288-C291 PolarHBondContact O-SG 2.74Å; H289-C291 PolarHBondContact O-N 3.5Å; H289-C291 VanDerWaalsContact O-N 3.09Å
292	I	90.8	Very high	85.2	Confident	35 Å²	35	31.4 Å²	31.4	18%	0.179	17%	0.165	C	C	.	.	H	α-helix	trans	-82.4	-29.8	-175.1	-53.2	-60.3	0	0	0	112	V243 F247 H289 I295 I296	V243-I292 HydrophobicContact CG1-CB 4.5Å; V243-I292 HydrophobicContact CG1-CG2 3.7Å; F247-I292 HydrophobicContact CE1-CD1 4.29Å; F247-I292 HydrophobicContact CE1-CG1 3.88Å; F247-I292 HydrophobicContact CZ-CD1 4.18Å; F247-I292 HydrophobicContact CZ-CG1 3.93Å; H289-I292 WeakPolarHBondContact O-CB 3.33Å; H289-I292 PolarHBondContact O-N 3.28Å; I292-I295 HydrophobicContact CD1-CD1 4.23Å; I292-I295 WeakPolarHBondContact O-CA 3.31Å; I292-I295 VanDerWaalsContact O-CB 3.32Å; I292-I295 WeakPolarHBondContact O-CB 3.39Å; I292-I295 PolarHBondContact O-N 2.67Å; I292-I296 HydrophobicContact CG2-CD1 3.98Å; I292-I296 HydrophobicContact CG2-CG1 3.99Å; I292-I296 WeakPolarHBondContact O-CG1 3.49Å; I292-I296 PolarHBondContact O-N 2.88Å
293	N	86.8	Confident	84	Confident	0 Å²	0	36.8 Å²	36.8	0%	0	19%	0.187	C	C	.	.	H	α-helix	trans	-55.3	-50.6	-179.4	-76.9	-29.9	0	0	0	113.4	D76 I295 I296 Y297	D76-N293 PolarHBondContact OD2-ND2 3.01Å; N293-I295 VanDerWaalsContact C-N 3.29Å; N293-I295 PolarHBondContact O-N 3.4Å; N293-I296 PolarHBondContact O-N 3.17Å; N293-Y297 HydrophobicContact CB-CE2 4.32Å; N293-Y297 VanDerWaalsContact O-CD2 3.29Å; N293-Y297 WeakPolarHBondContact O-CD2 3.23Å; N293-Y297 VanDerWaalsContact O-CG 3.26Å; N293-Y297 PolarHBondContact O-N 3.45Å
294	P	86.6	Confident	82.9	Confident	11 Å²	11	35.7 Å²	35.7	7%	0.071	18%	0.181	C	C	.	.	H	α-helix	trans	-58.6	-37.2	173.4	-25.6	34.6	0	0	0	114	G47 N48 V51 Y297 A298	G47-P294 VanDerWaalsContact C-CG 3.41Å; N48-P294 WeakPolarHBondContact OD1-CG 3.42Å; V51-P294 HydrophobicContact CG2-CB 4.09Å; V51-P294 HydrophobicContact CG2-CG 4.19Å; P294-Y297 PolarHBondContact O-N 2.88Å; P294-A298 PolarHBondContact O-N 3.49Å
295	I	85.9	Confident	82.1	Confident	78 Å²	78	41.5 Å²	41.5	40%	0.4	20%	0.202	S	C	.	.	H	α-helix	trans	-62.9	-48.1	177.3	-62.8	175.8	0	0	0	109.4	I292 N293 Y297 A298 F299	I292-I295 HydrophobicContact CD1-CD1 4.23Å; I292-I295 WeakPolarHBondContact O-CA 3.31Å; I292-I295 VanDerWaalsContact O-CB 3.32Å; I292-I295 WeakPolarHBondContact O-CB 3.39Å; I292-I295 PolarHBondContact O-N 2.67Å; N293-I295 VanDerWaalsContact C-N 3.29Å; N293-I295 PolarHBondContact O-N 3.4Å; I295-Y297 VanDerWaalsContact C-N 3.27Å; I295-Y297 PolarHBondContact O-N 2.96Å; I295-A298 PolarHBondContact O-N 3.23Å; I295-A298 VanDerWaalsContact O-N 3.13Å; I295-F299 HydrophobicContact CG2-CD2 3.62Å; I295-F299 HydrophobicContact CG2-CE2 3.75Å; I295-F299 VanDerWaalsContact O-CD2 3.23Å; I295-F299 WeakPolarHBondContact O-CD2 3.25Å; I295-F299 PolarHBondContact O-N 3.43Å
296	I	84.4	Confident	81.3	Confident	10 Å²	10	42.7 Å²	42.7	5%	0.051	21%	0.209	C	C	.	.	H	α-helix	trans	-56.7	-43.5	175.5	-63.8	169.7	0	0	0	110.5	L236 T239 I240 V243 I292 N293 A298 F299 V300	L236-I296 HydrophobicContact CD1-CG2 3.93Å; T239-I296 HydrophobicContact CG2-CG2 4.17Å; I240-I296 HydrophobicContact CG1-CD1 4.35Å; I240-I296 HydrophobicContact CG1-CG2 3.85Å; V243-I296 HydrophobicContact CB-CD1 3.93Å; V243-I296 HydrophobicContact CG1-CD1 3.97Å; V243-I296 HydrophobicContact CG2-CD1 4Å; I292-I296 HydrophobicContact CG2-CD1 3.98Å; I292-I296 HydrophobicContact CG2-CG1 3.99Å; I292-I296 WeakPolarHBondContact O-CG1 3.49Å; I292-I296 PolarHBondContact O-N 2.88Å; N293-I296 PolarHBondContact O-N 3.17Å; I296-A298 PolarHBondContact O-N 2.9Å; I296-F299 PolarHBondContact O-N 3.46Å; I296-V300 HydrophobicContact CG2-CB 4.25Å; I296-V300 HydrophobicContact CG2-CG2 4.04Å; I296-V300 WeakPolarHBondContact O-CA 3.4Å; I296-V300 VanDerWaalsContact O-CB 3.22Å; I296-V300 WeakPolarHBondContact O-CB 3.43Å; I296-V300 WeakPolarHBondContact O-CG2 3.36Å; I296-V300 PolarHBondContact O-N 3.06Å
297	Y	80.6	Confident	80.5	Confident	12 Å²	12	46.7 Å²	46.7	5%	0.047	22%	0.224	C	C	.	.	H	α-helix	trans	-65	-38.4	178.7	-56	-29.2	0	0	0	112.9	V51 L69 L72 L236 I240 N293 P294 I295 G301	V51-Y297 HydrophobicContact CG1-CD2 4.28Å; V51-Y297 HydrophobicContact CG1-CE2 4.18Å; V51-Y297 HydrophobicContact CG2-CD2 3.73Å; V51-Y297 HydrophobicContact CG2-CE2 4.2Å; L69-Y297 HydrophobicContact CD2-CE1 4.05Å; L69-Y297 WeakPolarHBondContact CD2-OH 3.25Å; L72-Y297 WeakPolarHBondContact CD2-OH 3.36Å; L236-Y297 HydrophobicContact CD1-CD1 4.32Å; I240-Y297 HydrophobicContact CD1-CE1 3.64Å; I240-Y297 HydrophobicContact CG1-CE1 4.27Å; N293-Y297 HydrophobicContact CB-CE2 4.32Å; N293-Y297 VanDerWaalsContact O-CD2 3.29Å; N293-Y297 WeakPolarHBondContact O-CD2 3.23Å; N293-Y297 VanDerWaalsContact O-CG 3.26Å; N293-Y297 PolarHBondContact O-N 3.45Å; P294-Y297 PolarHBondContact O-N 2.88Å; I295-Y297 VanDerWaalsContact C-N 3.27Å; I295-Y297 PolarHBondContact O-N 2.96Å; Y297-G301 WeakPolarHBondContact O-CA 3.17Å; Y297-G301 PolarHBondContact O-N 3.46Å
298	A	76.4	Confident	79.8	Confident	31 Å²	31	47.4 Å²	47.4	26%	0.256	23%	0.228	S	C	.	.	H	α-helix	trans	-66.9	-41.2	178.5	0	0	0	0	0	112.7	P294 I295 I296 L308	P294-A298 PolarHBondContact O-N 3.49Å; I295-A298 PolarHBondContact O-N 3.23Å; I295-A298 VanDerWaalsContact O-N 3.13Å; I296-A298 PolarHBondContact O-N 2.9Å; A298-L308 HydrophobicContact CB-CD1 4.26Å
299	F	72.4	Confident	78.9	Confident	171 Å²	171	50.8 Å²	50.8	75%	0.75	25%	0.245	S	C	*	.	H	α-helix	trans	-89.6	-39.1	-175.8	-72.4	-74.3	0	0	0	113.7	I295 I296	I295-F299 HydrophobicContact CG2-CD2 3.62Å; I295-F299 HydrophobicContact CG2-CE2 3.75Å; I295-F299 VanDerWaalsContact O-CD2 3.23Å; I295-F299 WeakPolarHBondContact O-CD2 3.25Å; I295-F299 PolarHBondContact O-N 3.43Å; I296-F299 PolarHBondContact O-N 3.46Å
300	V	69	Low	78.2	Confident	34 Å²	34	54 Å²	54	21%	0.206	27%	0.265	C	S	.	.	H	α-helix	trans	-96.3	-27.1	-174.4	-171.6	0	0	0	0	111.7	L236 T239 I296 E302	L236-V300 HydrophobicContact CB-CG1 4.27Å; L236-V300 HydrophobicContact CD1-CB 3.74Å; L236-V300 HydrophobicContact CD1-CG1 3.73Å; T239-V300 HydrophobicContact CG2-CG2 4.26Å; I296-V300 HydrophobicContact CG2-CB 4.25Å; I296-V300 HydrophobicContact CG2-CG2 4.04Å; I296-V300 WeakPolarHBondContact O-CA 3.4Å; I296-V300 VanDerWaalsContact O-CB 3.22Å; I296-V300 WeakPolarHBondContact O-CB 3.43Å; I296-V300 WeakPolarHBondContact O-CG2 3.36Å; I296-V300 PolarHBondContact O-N 3.06Å; V300-E302 PolarHBondContact O-N 3.14Å
301	G	68.1	Low	77.5	Confident	10 Å²	10	55.1 Å²	55.1	10%	0.103	27%	0.269	C	S	.	.			trans	-91.1	86.9	-177	0	0	0	0	0	113.8	Y297 K303 F304 R305	Y297-G301 WeakPolarHBondContact O-CA 3.17Å; Y297-G301 PolarHBondContact O-N 3.46Å; G301-K303 PolarHBondContact O-N 3.45Å; G301-K303 VanDerWaalsContact O-N 3.12Å; G301-F304 WeakPolarHBondContact O-CA 3.35Å; G301-F304 WeakPolarHBondContact O-CB 3.38Å; G301-F304 PolarHBondContact O-N 3.24Å; G301-R305 PolarHBondContact O-N 2.93Å
302	E	69	Low	76.9	Confident	79 Å²	79	58.9 Å²	58.9	37%	0.369	28%	0.284	S	S	.	.	H	α-helix	trans	-51.2	-40.1	176.6	-70.9	175.1	-176.7	0	0	113.6	R232 V300 N306	R232-E302 IonicContact CZ-OE1 3.87Å; R232-E302 IonicContact CZ-OE2 3.73Å; R232-E302 IonicContact NE-OE1 3.32Å; R232-E302 IonicContact NE-OE2 3.81Å; R232-E302 IonicContact NH1-OE1 3Å; R232-E302 IonicContact NH1-OE2 3.89Å; R232-E302 PolarHBondContact NH1-OE2 3.15Å; V300-E302 PolarHBondContact O-N 3.14Å; E302-N306 PolarHBondContact O-N 2.88Å; E302-N306 VanDerWaalsContact O-N 3.14Å
303	K	68.7	Low	76.1	Confident	130 Å²	130	63.2 Å²	63.2	57%	0.565	30%	0.304	S	S	*	.	H	α-helix	trans	-65.4	-43.1	176.4	-69.8	-174	179.1	-177.1	0	111.9	G301 R305 N306 Y307	G301-K303 PolarHBondContact O-N 3.45Å; G301-K303 VanDerWaalsContact O-N 3.12Å; K303-R305 VanDerWaalsContact C-N 3.34Å; K303-N306 PolarHBondContact O-N 3.4Å; K303-Y307 HydrophobicContact CB-CE2 4.34Å; K303-Y307 WeakPolarHBondContact O-CD2 3.32Å; K303-Y307 PolarHBondContact O-N 3.25Å
304	F	68.1	Low	75.3	Confident	20 Å²	20	69.8 Å²	69.8	9%	0.088	33%	0.332	C	S	.	.	H	α-helix	trans	-66.1	-40.4	-179.3	-172.7	-101.6	0	0	0	110.7	V51 I54 G301 N306 Y307 L308	V51-F304 HydrophobicContact CB-CE2 4.44Å; V51-F304 HydrophobicContact CB-CZ 4.33Å; V51-F304 HydrophobicContact CG2-CE1 4.43Å; V51-F304 HydrophobicContact CG2-CE2 4.06Å; V51-F304 HydrophobicContact CG2-CZ 3.58Å; I54-F304 HydrophobicContact CB-CE2 4.03Å; I54-F304 HydrophobicContact CD1-CD2 4.41Å; I54-F304 HydrophobicContact CD1-CE1 4.36Å; I54-F304 HydrophobicContact CD1-CE2 3.65Å; I54-F304 HydrophobicContact CD1-CZ 3.61Å; I54-F304 HydrophobicContact CG1-CE2 4.45Å; I54-F304 HydrophobicContact CG2-CD2 4.05Å; I54-F304 HydrophobicContact CG2-CE2 3.85Å; G301-F304 WeakPolarHBondContact O-CA 3.35Å; G301-F304 WeakPolarHBondContact O-CB 3.38Å; G301-F304 PolarHBondContact O-N 3.24Å; F304-N306 PolarHBondContact O-N 3.06Å; F304-Y307 PolarHBondContact O-N 3.18Å; F304-L308 HydrophobicContact CD1-CD1 3.54Å; F304-L308 HydrophobicContact CD1-CG 4.04Å; F304-L308 HydrophobicContact CE1-CD1 3.41Å; F304-L308 VanDerWaalsContact CE1-CD1 3.41Å; F304-L308 HydrophobicContact CE1-CD2 4.28Å; F304-L308 HydrophobicContact CE1-CG 3.79Å; F304-L308 HydrophobicContact CZ-CD1 4.37Å; F304-L308 HydrophobicContact CZ-CG 4.31Å; F304-L308 WeakPolarHBondContact O-CB 3.24Å; F304-L308 PolarHBondContact O-N 3.16Å
305	R	74.9	Confident	74.5	Confident	135 Å²	135	73.5 Å²	73.5	51%	0.509	35%	0.349	S	S	.	.	H	α-helix	trans	-58.1	-44	172.3	-167.9	178.5	70.4	-174.5	3.5	112.8	G301 K303 Y307 L308 L309	G301-R305 PolarHBondContact O-N 2.93Å; K303-R305 VanDerWaalsContact C-N 3.34Å; R305-Y307 VanDerWaalsContact C-N 3.35Å; R305-Y307 PolarHBondContact O-N 2.94Å; R305-L308 WeakPolarHBondContact O-CB 3.26Å; R305-L308 PolarHBondContact O-N 3.28Å; R305-L309 WeakPolarHBondContact O-CG 3.5Å; R305-L309 PolarHBondContact O-N 3.03Å
306	N	76.8	Confident	73.5	Confident	92 Å²	92	72.9 Å²	72.9	49%	0.492	35%	0.346	S	S	.	.	H	α-helix	trans	-64.8	-39.3	176.4	-73.3	-2.3	0	0	0	111.9	E302 K303 F304 L309 V310	E302-N306 PolarHBondContact O-N 2.88Å; E302-N306 VanDerWaalsContact O-N 3.14Å; K303-N306 PolarHBondContact O-N 3.4Å; F304-N306 PolarHBondContact O-N 3.06Å; N306-L309 PolarHBondContact O-N 3.4Å; N306-V310 WeakPolarHBondContact O-CG2 3.22Å; N306-V310 PolarHBondContact O-N 3.41Å
307	Y	75.3	Confident	72.3	Confident	83 Å²	83	74.5 Å²	74.5	33%	0.325	36%	0.36	S	S	.	.	H	α-helix	trans	-67.9	-38.2	174.6	-70.5	-61.1	0	0	0	112.8	I54 C58 K59 K303 F304 R305 V310 F311	I54-Y307 HydrophobicContact CG2-CG 4.28Å; C58-Y307 HydrophobicContact CB-CD1 3.71Å; C58-Y307 HydrophobicContact CB-CE1 4.26Å; C58-Y307 HydrophobicContact CB-CG 4.27Å; K59-Y307 HydrophobicContact CD-CE2 4.28Å; K59-Y307 HydrophobicContact CG-CD2 4.16Å; K59-Y307 HydrophobicContact CG-CE2 3.79Å; K303-Y307 HydrophobicContact CB-CE2 4.34Å; K303-Y307 WeakPolarHBondContact O-CD2 3.32Å; K303-Y307 PolarHBondContact O-N 3.25Å; F304-Y307 PolarHBondContact O-N 3.18Å; R305-Y307 VanDerWaalsContact C-N 3.35Å; R305-Y307 PolarHBondContact O-N 2.94Å; Y307-V310 PolarHBondContact O-N 3.24Å; Y307-F311 VanDerWaalsContact O-CB 3.25Å; Y307-F311 WeakPolarHBondContact O-CB 3.41Å; Y307-F311 PolarHBondContact O-N 3.14Å
308	L	75.1	Confident	71	Confident	20 Å²	20	81.3 Å²	81.3	11%	0.105	39%	0.39	C	S	.	.	H	α-helix	trans	-56	-52.8	171.1	-85.1	167.1	0	0	0	110.1	L50 I54 A298 F304 R305 V310 F311 F312	L50-L308 HydrophobicContact CD1-CD2 4.24Å; L50-L308 HydrophobicContact CD2-CD2 3.3Å; L50-L308 HydrophobicContact CG-CD2 3.74Å; I54-L308 HydrophobicContact CD1-CD2 3.52Å; I54-L308 HydrophobicContact CD1-CG 3.68Å; A298-L308 HydrophobicContact CB-CD1 4.26Å; F304-L308 HydrophobicContact CD1-CD1 3.54Å; F304-L308 HydrophobicContact CD1-CG 4.04Å; F304-L308 HydrophobicContact CE1-CD1 3.41Å; F304-L308 VanDerWaalsContact CE1-CD1 3.41Å; F304-L308 HydrophobicContact CE1-CD2 4.28Å; F304-L308 HydrophobicContact CE1-CG 3.79Å; F304-L308 HydrophobicContact CZ-CD1 4.37Å; F304-L308 HydrophobicContact CZ-CG 4.31Å; F304-L308 WeakPolarHBondContact O-CB 3.24Å; F304-L308 PolarHBondContact O-N 3.16Å; R305-L308 WeakPolarHBondContact O-CB 3.26Å; R305-L308 PolarHBondContact O-N 3.28Å; L308-V310 VanDerWaalsContact C-N 3.35Å; L308-V310 PolarHBondContact O-N 3.28Å; L308-F311 WeakPolarHBondContact O-CB 3.39Å; L308-F311 PolarHBondContact O-N 2.89Å; L308-F311 VanDerWaalsContact O-N 3.1Å; L308-F312 HydrophobicContact CB-CD2 4.4Å; L308-F312 HydrophobicContact CB-CE2 4.48Å; L308-F312 HydrophobicContact CD2-CD2 4.48Å; L308-F312 HydrophobicContact CD2-CE2 3.9Å; L308-F312 WeakPolarHBondContact O-CD2 3.35Å; L308-F312 PolarHBondContact O-N 3.22Å
309	L	75.8	Confident	69.9	Low	92 Å²	92	89.4 Å²	89.4	48%	0.482	41%	0.414	S	S	.	.	H	α-helix	trans	-57.7	-45.8	179.6	-71.6	170.4	0	0	0	112.1	R305 N306 F311 F312 Q313	R305-L309 WeakPolarHBondContact O-CG 3.5Å; R305-L309 PolarHBondContact O-N 3.03Å; N306-L309 PolarHBondContact O-N 3.4Å; L309-F311 VanDerWaalsContact C-N 3.34Å; L309-F311 PolarHBondContact O-N 3.48Å; L309-F312 PolarHBondContact O-N 2.91Å; L309-Q313 WeakPolarHBondContact O-CB 3.44Å; L309-Q313 VanDerWaalsContact O-CG 3.25Å; L309-Q313 WeakPolarHBondContact O-CG 3.35Å; L309-Q313 PolarHBondContact O-N 3.47Å
310	V	77.3	Confident	68.8	Low	75 Å²	75	88.3 Å²	88.3	46%	0.455	41%	0.41	S	S	.	.	H	α-helix	trans	-64.1	-38.8	176.3	172.4	0	0	0	0	111.6	N306 Y307 L308 Q313 K314	N306-V310 WeakPolarHBondContact O-CG2 3.22Å; N306-V310 PolarHBondContact O-N 3.41Å; Y307-V310 PolarHBondContact O-N 3.24Å; L308-V310 VanDerWaalsContact C-N 3.35Å; L308-V310 PolarHBondContact O-N 3.28Å; V310-Q313 PolarHBondContact O-N 3.06Å; V310-K314 WeakPolarHBondContact O-CB 3.45Å; V310-K314 PolarHBondContact O-N 3.47Å
311	F	74.8	Confident	67.7	Low	26 Å²	26	90.1 Å²	90.1	11%	0.114	42%	0.423	C	S	.	.	H	α-helix	trans	-65.2	-46.6	176.6	-177.8	-93.3	0	0	0	111.4	L50 L53 Y307 L308 L309 Q313 K314 H315	L50-F311 HydrophobicContact CD1-CD1 3.82Å; L50-F311 HydrophobicContact CD1-CE1 3.67Å; L50-F311 HydrophobicContact CD1-CZ 4.37Å; L53-F311 HydrophobicContact CD1-CZ 4.35Å; Y307-F311 VanDerWaalsContact O-CB 3.25Å; Y307-F311 WeakPolarHBondContact O-CB 3.41Å; Y307-F311 PolarHBondContact O-N 3.14Å; L308-F311 WeakPolarHBondContact O-CB 3.39Å; L308-F311 PolarHBondContact O-N 2.89Å; L308-F311 VanDerWaalsContact O-N 3.1Å; L309-F311 VanDerWaalsContact C-N 3.34Å; L309-F311 PolarHBondContact O-N 3.48Å; F311-Q313 PolarHBondContact O-N 3.47Å; F311-K314 PolarHBondContact O-N 3.44Å; F311-H315 AromaticContact CD2-CD2 3.69Å; F311-H315 AromaticContact CE2-CD2 3.65Å; F311-H315 HydrophobicContact CZ-CB 4.47Å; F311-H315 WeakPolarHBondContact O-CB 3.49Å; F311-H315 PolarHBondContact O-N 2.73Å
312	F	78.1	Confident	66.5	Low	92 Å²	92	98.8 Å²	98.8	40%	0.404	46%	0.458	S	S	.	.	I	π-helix	trans	-58.6	-46.4	173.8	-83.6	-75.6	0	0	0	111	L308 L309 K314 I316 A317	L308-F312 HydrophobicContact CB-CD2 4.4Å; L308-F312 HydrophobicContact CB-CE2 4.48Å; L308-F312 HydrophobicContact CD2-CD2 4.48Å; L308-F312 HydrophobicContact CD2-CE2 3.9Å; L308-F312 WeakPolarHBondContact O-CD2 3.35Å; L308-F312 PolarHBondContact O-N 3.22Å; L309-F312 PolarHBondContact O-N 2.91Å; F312-K314 PolarHBondContact O-N 3.28Å; F312-I316 HydrophobicContact CD1-CB 4.11Å; F312-I316 HydrophobicContact CD1-CD1 3.2Å; F312-I316 HydrophobicContact CD1-CG1 4.19Å; F312-I316 HydrophobicContact CD1-CG2 4.28Å; F312-I316 HydrophobicContact CE1-CD1 3.31Å; F312-I316 HydrophobicContact CG-CD1 4.19Å; F312-I316 HydrophobicContact CZ-CD1 4.36Å; F312-I316 CarbonylContact O-C 3.52Å; F312-I316 WeakPolarHBondContact O-CA 3.38Å; F312-I316 WeakPolarHBondContact O-CB 3.42Å; F312-I316 PolarHBondContact O-N 3.03Å; F312-A317 PolarHBondContact O-N 3.43Å
313	Q	75.1	Confident	65.3	Low	127 Å²	127	100.4 Å²	100.4	59%	0.593	48%	0.476	S	S	*	.	I	π-helix	trans	-62.9	-42.8	177.2	-73.7	171	-9	0	0	112.6	L309 V310 F311 A317 K318	L309-Q313 WeakPolarHBondContact O-CB 3.44Å; L309-Q313 VanDerWaalsContact O-CG 3.25Å; L309-Q313 WeakPolarHBondContact O-CG 3.35Å; L309-Q313 PolarHBondContact O-N 3.47Å; V310-Q313 PolarHBondContact O-N 3.06Å; F311-Q313 PolarHBondContact O-N 3.47Å; Q313-A317 WeakPolarHBondContact O-CB 3.28Å; Q313-K318 PolarHBondContact O-N 3.14Å
314	K	69.9	Low	63.9	Low	137 Å²	137	98 Å²	98	60%	0.596	48%	0.475	S	S	*	.	I	π-helix	trans	-78	-34.2	-174.2	-169.4	177.6	179.3	-175.5	0	113.9	V310 F311 F312 K318	V310-K314 WeakPolarHBondContact O-CB 3.45Å; V310-K314 PolarHBondContact O-N 3.47Å; F311-K314 PolarHBondContact O-N 3.44Å; F312-K314 PolarHBondContact O-N 3.28Å; K314-K318 WeakPolarHBondContact O-CB 3.45Å
315	H	68	Low	62.2	Low	89 Å²	89	102.8 Å²	102.8	41%	0.412	51%	0.511	S	S	.	.	I	π-helix	trans	-112.8	-32.2	-172.4	-72.2	-78	0	0	0	114.2	F311 R319	F311-H315 AromaticContact CD2-CD2 3.69Å; F311-H315 AromaticContact CE2-CD2 3.65Å; F311-H315 HydrophobicContact CZ-CB 4.47Å; F311-H315 WeakPolarHBondContact O-CB 3.49Å; F311-H315 PolarHBondContact O-N 2.73Å; H315-R319 WeakPolarHBondContact O-CB 3.35Å; H315-R319 WeakPolarHBondContact O-CG 3.5Å
316	I	65.1	Low	60.7	Low	65 Å²	65	103.5 Å²	103.5	33%	0.333	52%	0.523	S	S	.	.	I	π-helix	trans	-98.9	-51.1	-176.1	-67.5	167.5	0	0	0	109.6	F312 K318 R319 F320	F312-I316 HydrophobicContact CD1-CB 4.11Å; F312-I316 HydrophobicContact CD1-CD1 3.2Å; F312-I316 HydrophobicContact CD1-CG1 4.19Å; F312-I316 HydrophobicContact CD1-CG2 4.28Å; F312-I316 HydrophobicContact CE1-CD1 3.31Å; F312-I316 HydrophobicContact CG-CD1 4.19Å; F312-I316 HydrophobicContact CZ-CD1 4.36Å; F312-I316 CarbonylContact O-C 3.52Å; F312-I316 WeakPolarHBondContact O-CA 3.38Å; F312-I316 WeakPolarHBondContact O-CB 3.42Å; F312-I316 PolarHBondContact O-N 3.03Å; I316-K318 VanDerWaalsContact C-N 3.33Å; I316-K318 PolarHBondContact O-N 3.31Å; I316-R319 PolarHBondContact O-N 3.49Å; I316-R319 VanDerWaalsContact O-N 3.08Å; I316-F320 HydrophobicContact CG2-CD2 3.69Å; I316-F320 HydrophobicContact CG2-CE2 3.95Å; I316-F320 WeakPolarHBondContact O-CB 3.5Å; I316-F320 WeakPolarHBondContact O-CD2 3.47Å; I316-F320 PolarHBondContact O-N 3.47Å
317	A	58.9	Low	58.8	Low	44 Å²	44	107.7 Å²	107.7	36%	0.364	54%	0.538	S	S	.	.	I	π-helix	trans	-64.4	-35.6	176.1	0	0	0	0	0	112.1	F312 Q313 R319 C321	F312-A317 PolarHBondContact O-N 3.43Å; Q313-A317 WeakPolarHBondContact O-CB 3.28Å; A317-R319 PolarHBondContact O-N 3.03Å; A317-C321 WeakPolarHBondContact O-CA 3.44Å; A317-C321 WeakPolarHBondContact O-CB 3.34Å; A317-C321 PolarHBondContact O-N 3.18Å; A317-C321 PolarHBondContact O-SG 2.83Å; A317-C321 VanDerWaalsContact O-SG 3.41Å
318	K	54.1	Low	57.2	Low	155 Å²	155	112.8 Å²	112.8	67%	0.674	56%	0.564	S	S	*	*	H	α-helix	trans	-68.9	-27.7	172.2	-109.3	-175.5	179.8	-173.7	0	114.4	Q313 K314 I316 K322	Q313-K318 PolarHBondContact O-N 3.14Å; K314-K318 WeakPolarHBondContact O-CB 3.45Å; I316-K318 VanDerWaalsContact C-N 3.33Å; I316-K318 PolarHBondContact O-N 3.31Å; K318-K322 PolarHBondContact O-N 3.44Å
319	R	53	Low	55.3	Low	202 Å²	202	119.5 Å²	119.5	76%	0.762	60%	0.595	S	S	*	*	H	α-helix	trans	-80.6	-39.6	174.1	-88.7	-177.6	169.9	-178.1	-3.2	111.7	H315 I316 A317 K322	H315-R319 WeakPolarHBondContact O-CB 3.35Å; H315-R319 WeakPolarHBondContact O-CG 3.5Å; I316-R319 PolarHBondContact O-N 3.49Å; I316-R319 VanDerWaalsContact O-N 3.08Å; A317-R319 PolarHBondContact O-N 3.03Å; R319-K322 WeakPolarHBondContact O-CB 3.35Å; R319-K322 PolarHBondContact O-N 2.91Å
320	F	50	Low	53.3	Low	148 Å²	148	122.8 Å²	122.8	65%	0.649	61%	0.608	S	S	*	*	H	α-helix	trans	-75.4	-34.8	175.5	-85	-85.3	0	0	0	112.8	I316 K322 C323 C324	I316-F320 HydrophobicContact CG2-CD2 3.69Å; I316-F320 HydrophobicContact CG2-CE2 3.95Å; I316-F320 WeakPolarHBondContact O-CB 3.5Å; I316-F320 WeakPolarHBondContact O-CD2 3.47Å; I316-F320 PolarHBondContact O-N 3.47Å; F320-K322 PolarHBondContact O-N 3.46Å; F320-C323 CarbonylContact O-C 3.55Å; F320-C323 WeakPolarHBondContact O-CA 3.39Å; F320-C323 WeakPolarHBondContact O-CB 3.31Å; F320-C323 PolarHBondContact O-N 3.3Å; F320-C324 PolarHBondContact O-N 3.13Å; F320-C324 VanDerWaalsContact O-N 3.08Å
321	C	45.6	Very low	51.5	Low	72 Å²	72	123.7 Å²	123.7	49%	0.486	62%	0.624	S	S	.	*	T	Hydrogen-bonded Turn	trans	-70	-15.4	169.2	-78.3	0	0	0	0	113.2	A317 C323 C324	A317-C321 WeakPolarHBondContact O-CA 3.44Å; A317-C321 WeakPolarHBondContact O-CB 3.34Å; A317-C321 PolarHBondContact O-N 3.18Å; A317-C321 PolarHBondContact O-SG 2.83Å; A317-C321 VanDerWaalsContact O-SG 3.41Å; C321-C323 VanDerWaalsContact C-N 3.27Å; C321-C324 VanDerWaalsContact O-O 3.1Å
322	K	43.3	Very low	49.8	Very low	191 Å²	191	128.5 Å²	128.5	83%	0.83	66%	0.657	S	S	*	*	T	Hydrogen-bonded Turn	trans	-73.1	-20.9	164.8	-99.3	-171.5	174.6	-169	0	112.5	K318 R319 F320	K318-K322 PolarHBondContact O-N 3.44Å; R319-K322 WeakPolarHBondContact O-CB 3.35Å; R319-K322 PolarHBondContact O-N 2.91Å; F320-K322 PolarHBondContact O-N 3.46Å
323	C	43.7	Very low	47.8	Very low	113 Å²	113	133 Å²	133	76%	0.764	68%	0.68	S	S	*	*	T	Hydrogen-bonded Turn	trans	-95.8	-9.5	172.7	-79.6	0	0	0	0	113.8	F320 C321	F320-C323 CarbonylContact O-C 3.55Å; F320-C323 WeakPolarHBondContact O-CA 3.39Å; F320-C323 WeakPolarHBondContact O-CB 3.31Å; F320-C323 PolarHBondContact O-N 3.3Å; C321-C323 VanDerWaalsContact C-N 3.27Å
324	C	38.6	Very low	45.9	Very low	81 Å²	81	139.1 Å²	139.1	55%	0.547	70%	0.697	S	S	.	*			trans	-121.7	98.1	175	-74.2	0	0	0	0	110.5	F320 C321 I326	F320-C324 PolarHBondContact O-N 3.13Å; F320-C324 VanDerWaalsContact O-N 3.08Å; C321-C324 VanDerWaalsContact O-O 3.1Å; C324-I326 PolarHBondContact O-N 3.41Å
325	S	33.1	Very low	44.2	Very low	120 Å²	120	137.3 Å²	137.3	84%	0.839	71%	0.708	S	S	*	*	T	Hydrogen-bonded Turn	trans	-72.8	44.5	175.2	62.4	0	0	0	0	113.5
326	I	43.3	Very low	42.9	Very low	149 Å²	149	138.7 Å²	138.7	76%	0.764	73%	0.728	S	S	*	*	T	Hydrogen-bonded Turn	trans	-123.2	-10.2	-177	-67.6	-177.3	0	0	0	113.1	C324	C324-I326 PolarHBondContact O-N 3.41Å
327	F	36.7	Very low	41.6	Very low	181 Å²	181	140.8 Å²	140.8	79%	0.794	75%	0.748	S	S	*	*			trans	-116.7	35	-178.9	-116.4	-83.5	0	0	0	114.7
328	Q	41.1	Very low	40.5	Very low	189 Å²	189	144.9 Å²	144.9	88%	0.883	77%	0.768	S	S	*	*			trans	-109.3	68.4	172.7	-161.3	166.4	-15.9	0	0	110.4
329	Q	35.8	Very low	39.6	Very low	161 Å²	161	147.6 Å²	147.6	75%	0.752	78%	0.776	S	S	*	*			trans	-160.9	123.3	166	-146.1	169.8	5.2	0	0	105.7
330	E	34.8	Very low	38.5	Very low	162 Å²	162	143.8 Å²	143.8	76%	0.757	78%	0.775	S	S	*	*			cis	-155.8	142.8	-1	-109	159.7	-155.8	0	0	104.2
331	A	38.7	Very low	37.9	Very low	94 Å²	94	147.3 Å²	147.3	78%	0.777	78%	0.784	S	S	*	*	P	Polyproline II helix	trans	-101.1	124.2	162.9	0	0	0	0	0	107.4
332	P	39.1	Very low	37.2	Very low	126 Å²	126	149.6 Å²	149.6	82%	0.818	80%	0.801	S	S	*	*	P	Polyproline II helix	trans	-85.3	132.5	164.9	-6.8	25.1	0	0	0	109.9
333	E	35.3	Very low	36.9	Very low	188 Å²	188	145.1 Å²	145.1	88%	0.879	79%	0.79	S	S	*	*	P	Polyproline II helix	trans	-63.9	149.8	-175.3	-63	171.9	142.9	0	0	113.1	A335	E333-A335 PolarHBondContact O-N 3.35Å
334	R	36.4	Very low	36.3	Very low	254 Å²	254	143.5 Å²	143.5	96%	0.958	79%	0.792	S	S	*	*			trans	-67.8	107.6	164.2	-81.2	176.7	172.1	167	-3.6	108.9
335	A	34.5	Very low	36.2	Very low	100 Å²	100	148.1 Å²	148.1	83%	0.826	81%	0.806	S	S	*	*			trans	-90.9	127.5	157.5	0	0	0	0	0	109.7	E333	E333-A335 PolarHBondContact O-N 3.35Å
336	S	40.7	Very low	36.3	Very low	118 Å²	118	151.4 Å²	151.4	83%	0.825	81%	0.808	S	S	*	*			trans	-75.1	131.2	174.4	44.4	0	0	0	0	112.9
337	S	36.5	Very low	35.8	Very low	109 Å²	109	153.6 Å²	153.6	76%	0.762	82%	0.815	S	S	*	*			trans	-158	107.4	151.2	55.1	0	0	0	0	107.3
338	V	37	Very low	35.7	Very low	130 Å²	130	151.9 Å²	151.9	79%	0.788	81%	0.812	S	S	*	*				56.2	106.1	79.2	-175.8	0	0	0	0	113.2
339	Y	33.6	Very low	35.3	Very low	212 Å²	212	147.8 Å²	147.8	83%	0.831	81%	0.805	S	S	*	*			trans	51.1	130.1	150.6	-102.9	-105.8	0	0	0	118.5
340	T	31.6	Very low	35.2	Very low	122 Å²	122	146.5 Å²	146.5	75%	0.748	81%	0.808	S	S	*	*				-166.1	145.1	55.7	-48.7	0	0	0	0	111
341	R	36.5	Very low	35.2	Very low	221 Å²	221	142.8 Å²	142.8	83%	0.834	81%	0.812	S	S	*	*			trans	-84.9	120.6	172.6	-178.5	-179.3	-175.5	167.5	-0.9	108.6
342	S	31.3	Very low	34.9	Very low	120 Å²	120	149.7 Å²	149.7	84%	0.839	84%	0.835	S	S	*	*			trans	-100.7	110.4	167	-179.6	0	0	0	0	109.1
343	T	36.4	Very low	34.7	Very low	97 Å²	97	150.9 Å²	150.9	60%	0.595	84%	0.836	S	S	*	*			trans	-82.5	116.1	166.1	30	0	0	0	0	108.4
344	G	32.3	Very low	34.6	Very low	79 Å²	79	148.9 Å²	148.9	81%	0.814	83%	0.834	S	S	*	*			trans	-88.8	98.6	160.4	0	0	0	0	0	108.5
345	E	35.4	Very low	34.5	Very low	179 Å²	179	143.1 Å²	143.1	84%	0.836	83%	0.827	S	S	*	*	P	Polyproline II helix	trans	-85.7	133.1	167	-79.7	177.5	151.2	0	0	109.3
346	Q	35.1	Very low	34.5	Very low	188 Å²	188	145.6 Å²	145.6	88%	0.879	83%	0.827	S	S	*	*	P	Polyproline II helix	trans	-79.3	124.4	171.6	-73.9	169	-64.6	0	0	109.2
347	E	33.8	Very low	34.1	Very low	195 Å²	195	147.3 Å²	147.3	91%	0.911	83%	0.827	S	S	*	*	P	Polyproline II helix	trans	-77.3	122.4	165.2	-75.9	-177.8	152.2	0	0	110.2
348	I	34.3	Very low	34	Very low	145 Å²	145	149.9 Å²	149.9	74%	0.744	83%	0.831	S	S	*	*			trans	-131.5	106.8	161.8	-66.2	-178.3	0	0	0	108.4
349	S	31.8	Very low	33.8	Very low	104 Å²	104	151.3 Å²	151.3	73%	0.727	83%	0.834	S	S	*	*			trans	70.4	137.3	137	-54.7	0	0	0	0	124
350	V	34.2	Very low	33.8	Very low	134 Å²	134	146.6 Å²	146.6	81%	0.812	83%	0.834	S	S	*	*			trans	92.3	100	146.5	-154.7	0	0	0	0	117.9
351	G	34.7	Very low	34	Very low	83 Å²	83	148.7 Å²	148.7	86%	0.856	84%	0.842	S	S	*	*			trans	-107.9	132.2	149.3	0	0	0	0	0	109.5
352	L	31.7	Very low	33.7	Very low	239 Å²	239	142.1 Å²	142.1	100%	1.251	84%	0.842	S	S	*	*			trans	-125.3	0	158.7	-152.3	152.8	0	0	0	106

Retrieved 352 of 352 residues in 648.6 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).