A0A090N7U2_HUMAN Loading...

5'-nucleotidase

AlphaFold DB , UniProt , Accession A0A090N7U2, Species HUMAN (Homo sapiens, Human), Gene NT5C3, Length 285 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M87Confident96.6Very high79 Ų7973.2 Ų73.239%0.38938%0.384SS..  0120.30-70.5167.668.600106.9E3 F4 S279 I280 K283M1-E3 WeakPolarHBondContact CB-OE2 3.5Å; M1-E3 PolarHBondContact O-N 2.96Å; M1-F4 HydrophobicContact CB-CD2 3.6Å; M1-F4 HydrophobicContact CB-CE2 4.14Å; M1-F4 HydrophobicContact CB-CG 4.34Å; M1-F4 HydrophobicContact CE-CD2 4.25Å; M1-F4 HydrophobicContact CE-CE2 3.64Å; M1-F4 HydrophobicContact CE-CZ 4.49Å; M1-F4 WeakPolarHBondContact O-CB 3.38Å; M1-F4 PolarHBondContact O-N 3Å; M1-F4 HydrophobicContact SD-CD2 4.31Å; M1-F4 HydrophobicContact SD-CE2 3.89Å; M1-F4 HydrophobicContact SD-CZ 4.47Å; M1-S279 VanDerWaalsContact CE-C 3.42Å; M1-S279 VanDerWaalsContact CE-O 3.31Å; M1-S279 WeakPolarHBondContact CE-O 3.27Å; M1-S279 WeakPolarHBondContact CE-OG 3.41Å; M1-I280 HydrophobicContact CE-CG1 4.35Å; M1-K283 HydrophobicContact CE-CG 4.14Å; M1-K283 HydrophobicContact SD-CG 4.4Å
2P94.8Very high96.7Very high106 Ų10677.7 Ų77.769%0.68840%0.398SS*.G310 helixtrans-54.2-33.2-175.3-26.735.1000114.1F4 Q5P2-F4 PolarHBondContact O-N 3.18Å; P2-Q5 WeakPolarHBondContact O-CB 3.43Å; P2-Q5 PolarHBondContact O-N 3.41Å
3E97.4Very high96.9Very high55 Ų5578 Ų7826%0.25740%0.401SS..G310 helixtrans-60.2-30.7179.2-53.983.4175.700111.7M1 Q5 V9 V276 S279M1-E3 WeakPolarHBondContact CB-OE2 3.5Å; M1-E3 PolarHBondContact O-N 2.96Å; E3-Q5 VanDerWaalsContact C-N 3.26Å; E3-Q5 PolarHBondContact O-N 3.21Å; E3-V9 WeakPolarHBondContact O-CG2 3.46Å; E3-V276 HydrophobicContact CB-CG2 4.34Å; E3-S279 VanDerWaalsContact CD-CB 3.44Å
4F97.1Very high96.9Very high34 Ų3477.2 Ų77.215%0.14940%0.403CS..G310 helixtrans-79.6-5.7177.7-74.4-117.3000113.2M1 P2 I11 V17 I21 I266 V276 I280M1-F4 HydrophobicContact CB-CD2 3.6Å; M1-F4 HydrophobicContact CB-CE2 4.14Å; M1-F4 HydrophobicContact CB-CG 4.34Å; M1-F4 HydrophobicContact CE-CD2 4.25Å; M1-F4 HydrophobicContact CE-CE2 3.64Å; M1-F4 HydrophobicContact CE-CZ 4.49Å; M1-F4 WeakPolarHBondContact O-CB 3.38Å; M1-F4 PolarHBondContact O-N 3Å; M1-F4 HydrophobicContact SD-CD2 4.31Å; M1-F4 HydrophobicContact SD-CE2 3.89Å; M1-F4 HydrophobicContact SD-CZ 4.47Å; P2-F4 PolarHBondContact O-N 3.18Å; F4-I11 HydrophobicContact CD1-CD1 3.65Å; F4-I11 HydrophobicContact CE1-CD1 4.03Å; F4-V17 HydrophobicContact CE1-CG1 4.18Å; F4-I21 HydrophobicContact CE1-CD1 4.08Å; F4-I21 HydrophobicContact CZ-CD1 3.79Å; F4-I266 HydrophobicContact CE1-CD1 3.67Å; F4-I266 HydrophobicContact CZ-CD1 3.98Å; F4-V276 HydrophobicContact CD2-CG1 4.48Å; F4-V276 HydrophobicContact CE2-CG1 3.94Å; F4-V276 HydrophobicContact CZ-CG1 4.02Å; F4-I280 HydrophobicContact CE2-CD1 4.45Å; F4-I280 HydrophobicContact CE2-CG1 4.11Å; F4-I280 HydrophobicContact CZ-CD1 3.91Å; F4-I280 HydrophobicContact CZ-CG1 3.86Å
5Q96.8Very high97Very high161 Ų16177.4 Ų77.475%0.75241%0.409SS*.G310 helixtrans-95.9-2.3177.1-55.2-59.3-63.300112.6P2 E3P2-Q5 WeakPolarHBondContact O-CB 3.43Å; P2-Q5 PolarHBondContact O-N 3.41Å; E3-Q5 VanDerWaalsContact C-N 3.26Å; E3-Q5 PolarHBondContact O-N 3.21Å
6K97.3Very high97.1Very high68 Ų6881.3 Ų81.330%0.29642%0.417SS..SBendtrans-63.1145.6175.1-70.3-173.1177.6-168.90110.5S8 V9 E275K6-S8 PolarHBondContact O-N 3.23Å; K6-V9 HydrophobicContact CB-CG2 4.13Å; K6-V9 WeakPolarHBondContact O-CB 3.28Å; K6-V9 PolarHBondContact O-N 3.06Å; K6-E275 WeakPolarHBondContact CE-OE2 3.37Å; K6-E275 IonicContact NZ-OE1 2.66Å; K6-E275 PolarHBondContact NZ-OE1 3.28Å; K6-E275 IonicContact NZ-OE2 3.52Å; K6-E275 PolarHBondContact NZ-OE2 3.19Å
7S97.6Very high97.2Very high124 Ų12476.8 Ų76.887%0.86739%0.394SS*.THydrogen-bonded Turntrans-63.4-21.1178.555.10000113.9V9S7-V9 VanDerWaalsContact C-N 3.27Å
8S98.1Very high97.3Very high17 Ų1779.8 Ų79.812%0.11941%0.406CS..THydrogen-bonded Turntrans-71.4-20.117452.90000112.9K6 L268 V269 D271K6-S8 PolarHBondContact O-N 3.23Å; S8-L268 WeakPolarHBondContact O-CA 3.5Å; S8-V269 VanDerWaalsContact CB-O 3.25Å; S8-V269 WeakPolarHBondContact CB-O 3.46Å; S8-V269 PolarHBondContact O-N 3.08Å; S8-D271 WeakPolarHBondContact CB-OD2 3.38Å; S8-D271 PolarHBondContact OG-OD2 3.47Å
9V98.8Very high97.3Very high18 Ų1882.3 Ų82.311%0.10942%0.416CS..EExtended strand (participates in β ladder)trans-87.7118.8-172.7-178.90000110.7E3 K6 S7 I11 I266 L268 V276E3-V9 WeakPolarHBondContact O-CG2 3.46Å; K6-V9 HydrophobicContact CB-CG2 4.13Å; K6-V9 WeakPolarHBondContact O-CB 3.28Å; K6-V9 PolarHBondContact O-N 3.06Å; S7-V9 VanDerWaalsContact C-N 3.27Å; V9-I11 HydrophobicContact CG1-CD1 3.85Å; V9-I11 HydrophobicContact CG1-CG1 3.99Å; V9-I266 HydrophobicContact CG1-CG2 4.24Å; V9-L268 HydrophobicContact CG2-CD2 3.83Å; V9-V276 HydrophobicContact CG2-CG2 3.9Å
10R98.8Very high97.4Very high103 Ų10379.1 Ų79.139%0.38940%0.4SS..EExtended strand (participates in β ladder)trans-123.5121.3177.2-56.2-62-65-83.7-5.2109.1L257 M261 V267 V269R10-L257 HydrophobicContact CB-CD1 4.32Å; R10-L257 HydrophobicContact CG-CD1 4.18Å; R10-L257 VanDerWaalsContact NH1-CD2 3.29Å; R10-M261 HydrophobicContact CB-CE 4.31Å; R10-M261 HydrophobicContact CB-CG 4.29Å; R10-M261 HydrophobicContact CB-SD 3.97Å; R10-V267 HydrophobicContact CB-CB 4.23Å; R10-V267 PolarHBondContact N-O 2.85Å; R10-V267 PolarHBondContact O-N 2.85Å; R10-V269 HydrophobicContact CG-CG2 3.72Å
11I98.8Very high97.5Very high40 Ų4076 Ų7621%0.20538%0.384CS..  trans-130121.8-177.5-64.2172.1000108F4 V9 P14 V17 I266F4-I11 HydrophobicContact CD1-CD1 3.65Å; F4-I11 HydrophobicContact CE1-CD1 4.03Å; V9-I11 HydrophobicContact CG1-CD1 3.85Å; V9-I11 HydrophobicContact CG1-CG1 3.99Å; I11-P14 HydrophobicContact CG2-CB 4.11Å; I11-V17 HydrophobicContact CG2-CB 4.35Å; I11-V17 HydrophobicContact CG2-CG2 3.67Å; I11-I266 HydrophobicContact CD1-CG1 4.14Å; I11-I266 HydrophobicContact CD1-CG2 4.45Å; I11-I266 HydrophobicContact CG1-CB 4.38Å; I11-I266 HydrophobicContact CG1-CG1 4.12Å; I11-I266 HydrophobicContact CG1-CG2 4.17Å
12K98.5Very high98Very high127 Ų12775 Ų7555%0.55238%0.384SS*.SBendtrans-73.6-41.9179.6-172.8173.6-179.9175.50112.1M261 D262K12-M261 HydrophobicContact CB-CB 4.31Å; K12-M261 HydrophobicContact CB-CE 4.05Å; K12-M261 VanDerWaalsContact CB-O 3.28Å; K12-M261 WeakPolarHBondContact CB-O 3.42Å; K12-M261 WeakPolarHBondContact CD-O 3.32Å; K12-D262 WeakPolarHBondContact CD-OD1 3.45Å; K12-D262 WeakPolarHBondContact CE-OD1 3.45Å; K12-D262 VanDerWaalsContact NZ-CG 3.33Å; K12-D262 IonicContact NZ-OD1 2.74Å; K12-D262 PolarHBondContact NZ-OD1 3.38Å; K12-D262 IonicContact NZ-OD2 3.58Å
13N98.4Very high98.2Very high82 Ų8270.1 Ų70.144%0.43935%0.354SS..  trans-130.688.6-179-171.8-20.5000110.8T15 R16 V17N13-T15 PolarHBondContact O-N 3.43Å; N13-T15 PolarHBondContact OD1-N 3.15Å; N13-R16 HydrophobicContact CB-CB 4.04Å; N13-R16 VanDerWaalsContact CG-CB 3.5Å; N13-R16 PolarHBondContact O-N 2.89Å; N13-R16 PolarHBondContact OD1-N 3.16Å; N13-R16 VanDerWaalsContact OD1-N 3.08Å; N13-V17 PolarHBondContact O-N 2.86Å; N13-V17 VanDerWaalsContact O-N 3.16Å
14P98.1Very high98.3Very high67 Ų6767.5 Ų67.544%0.43534%0.341SS..Hα-helixtrans-65.2-36.6-175.724.5-33.2000113.1I11 R16 V17 E18I11-P14 HydrophobicContact CG2-CB 4.11Å; P14-R16 VanDerWaalsContact C-N 3.34Å; P14-R16 PolarHBondContact O-N 2.98Å; P14-V17 WeakPolarHBondContact O-CB 3.25Å; P14-V17 PolarHBondContact O-N 3.42Å; P14-V17 VanDerWaalsContact O-N 3.15Å; P14-E18 WeakPolarHBondContact O-CG 3.47Å; P14-E18 PolarHBondContact O-N 3.49Å
15T98.4Very high98.4Very high80 Ų8069.5 Ų69.549%0.49135%0.352SS..Hα-helixtrans-61.4-42.8177.3-53.90000111.5N13 V17 E18 E19N13-T15 PolarHBondContact O-N 3.43Å; N13-T15 PolarHBondContact OD1-N 3.15Å; T15-V17 PolarHBondContact O-N 2.65Å; T15-E18 WeakPolarHBondContact O-CB 3.23Å; T15-E18 PolarHBondContact O-N 3.34Å; T15-E19 WeakPolarHBondContact O-CG 3.49Å; T15-E19 PolarHBondContact O-N 3.45Å
16R98.3Very high98.4Very high140 Ų14069.9 Ų69.953%0.52835%0.352SS..Hα-helixtrans-62.7-41.8174.1176.4176.2169.8144.91.7112N13 P14 E18 E19 I20 D265N13-R16 HydrophobicContact CB-CB 4.04Å; N13-R16 VanDerWaalsContact CG-CB 3.5Å; N13-R16 PolarHBondContact O-N 2.89Å; N13-R16 PolarHBondContact OD1-N 3.16Å; N13-R16 VanDerWaalsContact OD1-N 3.08Å; P14-R16 VanDerWaalsContact C-N 3.34Å; P14-R16 PolarHBondContact O-N 2.98Å; R16-E18 VanDerWaalsContact C-N 3.32Å; R16-E18 PolarHBondContact O-N 3.29Å; R16-E19 PolarHBondContact O-N 2.71Å; R16-I20 HydrophobicContact CG-CD1 3.95Å; R16-I20 VanDerWaalsContact O-CG1 3.28Å; R16-I20 WeakPolarHBondContact O-CG1 3.16Å; R16-I20 PolarHBondContact O-N 2.82Å; R16-D265 IonicContact NE-OD1 2.85Å
17V98.7Very high98.5Very high4 Ų467.5 Ų67.52%0.02435%0.347CS..Hα-helixtrans-60.5-43.7175.9169.20000111.1F4 I11 N13 P14 T15 I20 I21 L244 D265 I266F4-V17 HydrophobicContact CE1-CG1 4.18Å; I11-V17 HydrophobicContact CG2-CB 4.35Å; I11-V17 HydrophobicContact CG2-CG2 3.67Å; N13-V17 PolarHBondContact O-N 2.86Å; N13-V17 VanDerWaalsContact O-N 3.16Å; P14-V17 WeakPolarHBondContact O-CB 3.25Å; P14-V17 PolarHBondContact O-N 3.42Å; P14-V17 VanDerWaalsContact O-N 3.15Å; T15-V17 PolarHBondContact O-N 2.65Å; V17-I20 PolarHBondContact O-N 2.88Å; V17-I21 HydrophobicContact CG1-CD1 3.66Å; V17-I21 HydrophobicContact CG1-CG1 4.37Å; V17-I21 WeakPolarHBondContact O-CG1 3.44Å; V17-I21 PolarHBondContact O-N 3.32Å; V17-L244 HydrophobicContact CG1-CD1 4.38Å; V17-D265 HydrophobicContact CG2-CB 3.87Å; V17-D265 WeakPolarHBondContact CG2-O 3.3Å; V17-I266 HydrophobicContact CG1-CD1 3.92Å; V17-I266 HydrophobicContact CG1-CG1 4.02Å; V17-I266 HydrophobicContact CG2-CG1 4.11Å
18E98.4Very high98.5Very high131 Ų13162.3 Ų62.361%0.61231%0.313SS*.Hα-helixtrans-61.7-43.3176.6-71.8171.9178.300112.1P14 T15 R16 I21 C22P14-E18 WeakPolarHBondContact O-CG 3.47Å; P14-E18 PolarHBondContact O-N 3.49Å; T15-E18 WeakPolarHBondContact O-CB 3.23Å; T15-E18 PolarHBondContact O-N 3.34Å; R16-E18 VanDerWaalsContact C-N 3.32Å; R16-E18 PolarHBondContact O-N 3.29Å; E18-I21 PolarHBondContact O-N 3.41Å; E18-C22 VanDerWaalsContact O-CB 3.23Å; E18-C22 WeakPolarHBondContact O-CB 3.15Å; E18-C22 PolarHBondContact O-N 3.49Å
19E98.6Very high98.5Very high127 Ų12763.1 Ų63.159%0.59332%0.32SS*.Hα-helixtrans-60.6-45.5175.7-73.4171.5178.900111.8T15 R16 C22 G23T15-E19 WeakPolarHBondContact O-CG 3.49Å; T15-E19 PolarHBondContact O-N 3.45Å; R16-E19 PolarHBondContact O-N 2.71Å; E19-C22 WeakPolarHBondContact O-CB 3.31Å; E19-C22 PolarHBondContact O-N 3.44Å; E19-G23 PolarHBondContact O-N 3.27Å
20I98.8Very high98.5Very high19 Ų1966.3 Ų66.310%0.09735%0.348CS..Hα-helixtrans-61.8-51.3177-66164.4000110R16 V17 C22 G23 L24 L244R16-I20 HydrophobicContact CG-CD1 3.95Å; R16-I20 VanDerWaalsContact O-CG1 3.28Å; R16-I20 WeakPolarHBondContact O-CG1 3.16Å; R16-I20 PolarHBondContact O-N 2.82Å; V17-I20 PolarHBondContact O-N 2.88Å; I20-C22 VanDerWaalsContact C-N 3.28Å; I20-C22 PolarHBondContact O-N 3.14Å; I20-G23 CarbonylContact O-C 3.56Å; I20-G23 WeakPolarHBondContact O-CA 3.31Å; I20-G23 PolarHBondContact O-N 2.57Å; I20-L24 HydrophobicContact CG2-CD1 4.44Å; I20-L24 HydrophobicContact CG2-CG 4.42Å; I20-L24 WeakPolarHBondContact O-CG 3.36Å; I20-L24 PolarHBondContact O-N 3.12Å; I20-L244 HydrophobicContact CB-CD1 4.46Å; I20-L244 HydrophobicContact CG2-CB 3.72Å; I20-L244 HydrophobicContact CG2-CD1 4.02Å; I20-L244 HydrophobicContact CG2-CG 4.45Å
21I98.8Very high98.5Very high14 Ų1464.6 Ų64.67%0.07234%0.344CS..Hα-helixtrans-60.4-39.3179.8-68.9170000110.9F4 V17 E18 G23 L24 I25 L244 I280F4-I21 HydrophobicContact CE1-CD1 4.08Å; F4-I21 HydrophobicContact CZ-CD1 3.79Å; V17-I21 HydrophobicContact CG1-CD1 3.66Å; V17-I21 HydrophobicContact CG1-CG1 4.37Å; V17-I21 WeakPolarHBondContact O-CG1 3.44Å; V17-I21 PolarHBondContact O-N 3.32Å; E18-I21 PolarHBondContact O-N 3.41Å; I21-G23 VanDerWaalsContact C-N 3.31Å; I21-G23 PolarHBondContact O-N 3.32Å; I21-L24 WeakPolarHBondContact O-CB 3.42Å; I21-L24 PolarHBondContact O-N 3.27Å; I21-I25 HydrophobicContact CG2-CD1 3.82Å; I21-I25 HydrophobicContact CG2-CG1 4.34Å; I21-I25 VanDerWaalsContact O-CG1 3.28Å; I21-I25 WeakPolarHBondContact O-CG1 3.45Å; I21-I25 PolarHBondContact O-N 2.85Å; I21-L244 HydrophobicContact CD1-CD2 4.41Å; I21-L244 HydrophobicContact CG1-CD2 3.97Å; I21-I280 HydrophobicContact CD1-CD1 4.38Å; I21-I280 HydrophobicContact CD1-CG1 4.16Å
22C98.6Very high98.5Very high57 Ų5762.7 Ų62.739%0.38533%0.334SS..Hα-helixtrans-60.5-41.3174.1-175.20000111.7E18 E19 I20 I25 K26E18-C22 VanDerWaalsContact O-CB 3.23Å; E18-C22 WeakPolarHBondContact O-CB 3.15Å; E18-C22 PolarHBondContact O-N 3.49Å; E19-C22 WeakPolarHBondContact O-CB 3.31Å; E19-C22 PolarHBondContact O-N 3.44Å; I20-C22 VanDerWaalsContact C-N 3.28Å; I20-C22 PolarHBondContact O-N 3.14Å; C22-I25 PolarHBondContact O-N 2.94Å; C22-K26 WeakPolarHBondContact O-CB 3.06Å; C22-K26 VanDerWaalsContact O-CG 3.28Å; C22-K26 WeakPolarHBondContact O-CG 3.49Å; C22-K26 PolarHBondContact O-N 3.03Å
23G98.7Very high98.5Very high5 Ų556.7 Ų56.75%0.05231%0.308CS..Hα-helixtrans-61.2-44.4171.900000113.3E19 I20 I21 K26 G27 N220 H242E19-G23 PolarHBondContact O-N 3.27Å; I20-G23 CarbonylContact O-C 3.56Å; I20-G23 WeakPolarHBondContact O-CA 3.31Å; I20-G23 PolarHBondContact O-N 2.57Å; I21-G23 VanDerWaalsContact C-N 3.31Å; I21-G23 PolarHBondContact O-N 3.32Å; G23-K26 PolarHBondContact O-N 2.9Å; G23-G27 PolarHBondContact O-N 3.2Å; G23-G27 VanDerWaalsContact O-N 3.07Å; G23-N220 PolarHBondContact O-ND2 3.34Å; G23-H242 VanDerWaalsContact C-CD2 3.47Å; G23-H242 VanDerWaalsContact CA-CD2 3.41Å; G23-H242 WeakPolarHBondContact CA-CD2 3.3Å; G23-H242 WeakPolarHBondContact CA-NE2 3.46Å
24L98.8Very high98.5Very high0 Ų052.8 Ų52.80%029%0.287CS..Hα-helixtrans-60.2-46.6175.6-61.7179.1000111.6I20 I21 K26 G27 G28 N220 I222 H242 L244 I280 I284I20-L24 HydrophobicContact CG2-CD1 4.44Å; I20-L24 HydrophobicContact CG2-CG 4.42Å; I20-L24 WeakPolarHBondContact O-CG 3.36Å; I20-L24 PolarHBondContact O-N 3.12Å; I21-L24 WeakPolarHBondContact O-CB 3.42Å; I21-L24 PolarHBondContact O-N 3.27Å; L24-K26 PolarHBondContact O-N 3.3Å; L24-G27 PolarHBondContact O-N 3.28Å; L24-G28 PolarHBondContact O-N 2.91Å; L24-N220 HydrophobicContact CD2-CB 3.67Å; L24-I222 HydrophobicContact CD1-CD1 4.27Å; L24-I222 HydrophobicContact CD1-CG1 3.89Å; L24-H242 HydrophobicContact CD2-CB 3.94Å; L24-L244 HydrophobicContact CD1-CB 3.91Å; L24-L244 HydrophobicContact CD1-CD2 4.17Å; L24-I280 HydrophobicContact CD1-CG2 4.47Å; L24-I284 HydrophobicContact CB-CD1 3.66Å; L24-I284 HydrophobicContact CB-CG1 4.03Å; L24-I284 HydrophobicContact CD1-CD1 4.1Å; L24-I284 HydrophobicContact CG-CD1 4.49Å
25I98.7Very high98.5Very high75 Ų7549.6 Ų49.639%0.38527%0.266SS..Hα-helixtrans-61.6-43.2177.8-67165.8000110.9I21 C22 G27 G28 K283 I284I21-I25 HydrophobicContact CG2-CD1 3.82Å; I21-I25 HydrophobicContact CG2-CG1 4.34Å; I21-I25 VanDerWaalsContact O-CG1 3.28Å; I21-I25 WeakPolarHBondContact O-CG1 3.45Å; I21-I25 PolarHBondContact O-N 2.85Å; C22-I25 PolarHBondContact O-N 2.94Å; I25-G27 VanDerWaalsContact C-N 3.29Å; I25-G27 PolarHBondContact O-N 3.27Å; I25-G28 PolarHBondContact O-N 3.19Å; I25-K283 HydrophobicContact CD1-CB 3.81Å; I25-K283 HydrophobicContact CG1-CB 4.07Å; I25-I284 HydrophobicContact CG1-CG1 3.98Å
26K98.6Very high98.6Very high170 Ų17045.8 Ų45.874%0.73924%0.243SC*.Hα-helixtrans-62.1-35.5177.6-76.9170.9-179.5171.90112.8C22 G23 L24C22-K26 WeakPolarHBondContact O-CB 3.06Å; C22-K26 VanDerWaalsContact O-CG 3.28Å; C22-K26 WeakPolarHBondContact O-CG 3.49Å; C22-K26 PolarHBondContact O-N 3.03Å; G23-K26 PolarHBondContact O-N 2.9Å; L24-K26 PolarHBondContact O-N 3.3Å
27G98.1Very high98.6Very high18 Ų1839.5 Ų39.519%0.18622%0.22CC..Hα-helixtrans-77.3-28.4177.100000113.8G23 L24 I25G23-G27 PolarHBondContact O-N 3.2Å; G23-G27 VanDerWaalsContact O-N 3.07Å; L24-G27 PolarHBondContact O-N 3.28Å; I25-G27 VanDerWaalsContact C-N 3.29Å; I25-G27 PolarHBondContact O-N 3.27Å
28G98.5Very high98.6Very high15 Ų1539.3 Ų39.316%0.15522%0.219CC..Hα-helixtrans60.4-163.2179.300000113.5L24 I25 A30 K31 L32L24-G28 PolarHBondContact O-N 2.91Å; I25-G28 PolarHBondContact O-N 3.19Å; G28-A30 VanDerWaalsContact C-N 3.31Å; G28-A30 PolarHBondContact O-N 3.13Å; G28-K31 PolarHBondContact O-N 3.02Å; G28-L32 PolarHBondContact O-N 3.48Å
29A98.2Very high98.6Very high34 Ų3433.9 Ų33.928%0.28119%0.194SC..Hα-helixtrans-56-41.3-178.600000113.6K31 L32 H144 I146 L285A29-K31 PolarHBondContact O-N 3Å; A29-K31 VanDerWaalsContact O-N 3.17Å; A29-L32 PolarHBondContact O-N 3.33Å; A29-L32 VanDerWaalsContact O-N 3.14Å; A29-H144 HydrophobicContact CB-CB 4.37Å; A29-I146 HydrophobicContact CB-CD1 3.8Å; A29-I146 WeakPolarHBondContact O-CD1 3.3Å; A29-L285 HydrophobicContact CB-CD2 3.55Å
30A97.8Very high98.6Very high84 Ų8428.2 Ų28.269%0.69417%0.168SC*.Hα-helixtrans-63.7-25.4-172.400000113.8G28G28-A30 VanDerWaalsContact C-N 3.31Å; G28-A30 PolarHBondContact O-N 3.13Å
31K98.4Very high98.6Very high67 Ų6727.3 Ų27.329%0.29116%0.163SC..Hα-helixtrans-102.1-9.2178-66.2-160.6176.2-162.20113.7G28 A29 N218 S219 N220 E241G28-K31 PolarHBondContact O-N 3.02Å; A29-K31 PolarHBondContact O-N 3Å; A29-K31 VanDerWaalsContact O-N 3.17Å; K31-N218 CarbonylContact O-C 3.28Å; K31-N218 WeakPolarHBondContact O-CA 3.49Å; K31-S219 PolarHBondContact O-N 2.93Å; K31-N220 HydrophobicContact CB-CB 4.11Å; K31-N220 WeakPolarHBondContact O-CA 3.49Å; K31-N220 WeakPolarHBondContact O-CB 3.39Å; K31-N220 PolarHBondContact O-N 2.86Å; K31-E241 IonicContact NZ-OE1 2.59Å; K31-E241 PolarHBondContact NZ-OE1 2.73Å; K31-E241 IonicContact NZ-OE2 3.02Å; K31-E241 PolarHBondContact NZ-OE2 3.02Å
32L98.8Very high98.6Very high1 Ų126.7 Ų26.71%0.00516%0.16CC..EExtended strand (participates in β ladder)trans-84.6140-170.2-174.566.7000111.7G28 A29 I34 I146 N218 N220 I222 L281 I284 L285G28-L32 PolarHBondContact O-N 3.48Å; A29-L32 PolarHBondContact O-N 3.33Å; A29-L32 VanDerWaalsContact O-N 3.14Å; L32-I34 HydrophobicContact CD1-CD1 4.48Å; L32-I34 HydrophobicContact CD2-CD1 4.38Å; L32-I34 HydrophobicContact CG-CD1 4.37Å; L32-I146 HydrophobicContact CB-CD1 4.33Å; L32-I146 HydrophobicContact CB-CG2 4.29Å; L32-I146 HydrophobicContact CD2-CD1 4.48Å; L32-I146 HydrophobicContact CD2-CG1 4.44Å; L32-I146 HydrophobicContact CD2-CG2 4.05Å; L32-I146 HydrophobicContact CG-CG2 3.94Å; L32-N218 PolarHBondContact O-ND2 3.18Å; L32-N220 CarbonylContact C-O 3.53Å; L32-N220 VanDerWaalsContact CA-O 3.32Å; L32-N220 WeakPolarHBondContact CA-O 3.29Å; L32-I222 HydrophobicContact CD1-CD1 4.17Å; L32-I222 HydrophobicContact CD1-CG1 4.11Å; L32-L281 HydrophobicContact CD2-CD2 3.85Å; L32-I284 HydrophobicContact CD2-CD1 4.47Å; L32-I284 HydrophobicContact CD2-CG2 4.15Å; L32-L285 HydrophobicContact CD2-CD2 4.28Å
33Q98.7Very high98.6Very high1 Ų124 Ų241%0.00514%0.141CC..EExtended strand (participates in β ladder)trans-139155.1160.262.2178.5-59.700110.6P147 N218 N220 I221 I222Q33-P147 HydrophobicContact CB-CB 4.28Å; Q33-N218 HydrophobicContact CB-CB 3.95Å; Q33-N218 HydrophobicContact CG-CB 4.03Å; Q33-N218 PolarHBondContact NE2-O 3.26Å; Q33-N220 PolarHBondContact N-O 3.37Å; Q33-I221 HydrophobicContact CG-CG1 3.82Å; Q33-I221 WeakPolarHBondContact O-CA 3.06Å; Q33-I222 PolarHBondContact O-N 3.2Å; Q33-I222 VanDerWaalsContact O-N 3.16Å
34I98.8Very high98.6Very high0 Ų025.6 Ų25.60%015%0.146CC..EExtended strand (participates in β ladder)trans-110.4132178.4-51.6-57.5000109.3L32 T36 F137 L141 I146 P147 V148 F149 I222 L281L32-I34 HydrophobicContact CD1-CD1 4.48Å; L32-I34 HydrophobicContact CD2-CD1 4.38Å; L32-I34 HydrophobicContact CG-CD1 4.37Å; I34-T36 HydrophobicContact CG2-CG2 4.38Å; I34-F137 HydrophobicContact CG2-CZ 4.04Å; I34-L141 HydrophobicContact CD1-CD2 3.95Å; I34-L141 HydrophobicContact CG1-CD1 3.91Å; I34-L141 HydrophobicContact CG1-CD2 3.6Å; I34-L141 HydrophobicContact CG1-CG 4.42Å; I34-I146 HydrophobicContact CG1-CG2 4.05Å; I34-P147 PolarHBondContact N-O 2.8Å; I34-V148 HydrophobicContact CB-CB 4.46Å; I34-V148 HydrophobicContact CB-CG1 4.29Å; I34-V148 HydrophobicContact CB-CG2 4.2Å; I34-V148 HydrophobicContact CG1-CG2 4.28Å; I34-V148 HydrophobicContact CG2-CG1 4.31Å; I34-F149 PolarHBondContact O-N 2.84Å; I34-I222 HydrophobicContact CD1-CB 3.82Å; I34-I222 HydrophobicContact CD1-CD1 4.22Å; I34-I222 HydrophobicContact CD1-CG1 4.4Å; I34-L281 HydrophobicContact CD1-CD2 4.24Å
35I98.8Very high98.6Very high0 Ų027 Ų270%015%0.152CC..EExtended strand (participates in β ladder)trans-123121171.6-61.3179.4000107.3F149 F212 I221 I222 L223 L224 M233 A234 V237I35-F149 WeakPolarHBondContact CA-O 3.38Å; I35-F149 HydrophobicContact CG1-CB 4.4Å; I35-F149 HydrophobicContact CG2-CD1 4.35Å; I35-F212 HydrophobicContact CD1-CE1 3.83Å; I35-F212 HydrophobicContact CD1-CZ 4.29Å; I35-F212 HydrophobicContact CG1-CE1 4.49Å; I35-I221 HydrophobicContact CB-CG2 4.37Å; I35-I221 HydrophobicContact CD1-CG2 3.98Å; I35-I221 HydrophobicContact CG1-CG2 4.1Å; I35-I222 PolarHBondContact N-O 3.38Å; I35-L223 CarbonylContact O-C 3.56Å; I35-L223 WeakPolarHBondContact O-CA 3.16Å; I35-L224 PolarHBondContact O-N 3.05Å; I35-M233 HydrophobicContact CG2-CB 3.51Å; I35-M233 HydrophobicContact CG2-CE 4.36Å; I35-A234 HydrophobicContact CD1-CB 3.92Å; I35-V237 HydrophobicContact CD1-CG2 3.52Å
36T98.9Very high98.5Very high0 Ų025.3 Ų25.30%015%0.147CC..EExtended strand (participates in β ladder)trans-142.9142.4-170.7-177.10000112I34 L42 V148 F149 I150 F151 L224I34-T36 HydrophobicContact CG2-CG2 4.38Å; T36-L42 HydrophobicContact CG2-CD1 3.79Å; T36-L42 HydrophobicContact CG2-CG 4.43Å; T36-V148 HydrophobicContact CG2-CG1 4.33Å; T36-F149 PolarHBondContact N-O 2.92Å; T36-I150 HydrophobicContact CG2-CB 4.38Å; T36-I150 HydrophobicContact CG2-CG1 3.87Å; T36-I150 CarbonylContact O-C 3.56Å; T36-I150 WeakPolarHBondContact O-CA 3.26Å; T36-F151 PolarHBondContact O-N 2.77Å; T36-L224 WeakPolarHBondContact CA-O 3.24Å; T36-L224 WeakPolarHBondContact OG1-CB 3.32Å
37D98.8Very high98.4Very high8 Ų821.7 Ų21.74%0.04313%0.129CC..  trans-70.1172.5158.5-174.458.7000110.1D39 T41 L42 K201 L224 M233D37-D39 PolarHBondContact OD2-N 2.9Å; D37-T41 HydrophobicContact CB-CG2 4.39Å; D37-L42 WeakPolarHBondContact O-CG 3.28Å; D37-K201 VanDerWaalsContact CG-NZ 3.31Å; D37-K201 IonicContact OD1-NZ 2.69Å; D37-K201 PolarHBondContact OD1-NZ 3.35Å; D37-L224 PolarHBondContact N-O 3.22Å; D37-M233 HydrophobicContact CB-CE 4.26Å; D37-M233 HydrophobicContact CB-SD 4.24Å
38F98.9Very high98.3Very high0 Ų029.4 Ų29.40%016%0.158CC..  trans-112.4-56.6176.9-175.6-102.2000113.3M40 T41 L42 S43 C55 L130 I150 L159 V162 I163F38-M40 PolarHBondContact O-N 3.34Å; F38-T41 PolarHBondContact O-N 3.39Å; F38-L42 HydrophobicContact CD2-CB 4.05Å; F38-L42 HydrophobicContact CD2-CD1 4Å; F38-L42 HydrophobicContact CE2-CB 4.41Å; F38-L42 PolarHBondContact O-N 3.2Å; F38-S43 PolarHBondContact O-N 3.37Å; F38-S43 PolarHBondContact O-OG 2.77Å; F38-C55 WeakPolarHBondContact CE1-SG 3.35Å; F38-L130 HydrophobicContact CE2-CD2 4.07Å; F38-L130 HydrophobicContact CZ-CD2 4.12Å; F38-I150 HydrophobicContact CB-CG2 3.84Å; F38-I150 HydrophobicContact CD2-CG2 4.31Å; F38-I150 HydrophobicContact CG-CG2 4.49Å; F38-L159 HydrophobicContact CB-CD1 3.55Å; F38-L159 HydrophobicContact CB-CG 4.24Å; F38-L159 HydrophobicContact CD1-CB 4.33Å; F38-L159 HydrophobicContact CD1-CD1 3.84Å; F38-L159 HydrophobicContact CD1-CG 3.73Å; F38-L159 HydrophobicContact CD2-CD1 3.96Å; F38-L159 HydrophobicContact CD2-CD2 4.22Å; F38-L159 HydrophobicContact CD2-CG 3.73Å; F38-L159 HydrophobicContact CE1-CB 4.34Å; F38-L159 HydrophobicContact CE1-CG 3.94Å; F38-L159 HydrophobicContact CE2-CD2 4.35Å; F38-L159 HydrophobicContact CE2-CG 3.96Å; F38-L159 HydrophobicContact CG-CD1 3.49Å; F38-L159 VanDerWaalsContact CG-CD1 3.49Å; F38-L159 HydrophobicContact CG-CG 3.61Å; F38-L159 HydrophobicContact CZ-CG 4.05Å; F38-V162 HydrophobicContact CZ-CB 4.09Å; F38-V162 HydrophobicContact CZ-CG1 3.86Å; F38-I163 HydrophobicContact CE2-CG2 3.66Å; F38-I163 HydrophobicContact CZ-CG2 4.3Å
39D98.6Very high98Very high17 Ų1732.6 Ų32.69%0.09119%0.191CC..THydrogen-bonded Turntrans-74.7124-168.7-83.9-49.2000109.1D37 T41 S43 T54 C55 D226D37-D39 PolarHBondContact OD2-N 2.9Å; D39-T41 PolarHBondContact O-N 3.02Å; D39-S43 WeakPolarHBondContact CA-OG 3.39Å; D39-T54 HydrophobicContact CB-CG2 4.24Å; D39-T54 WeakPolarHBondContact OD1-CA 3.5Å; D39-C55 PolarHBondContact OD1-N 2.83Å; D39-C55 PolarHBondContact OD2-N 2.83Å; D39-D226 VanDerWaalsContact O-OD1 3.14Å
40M98.3Very high97.9Very high8 Ų837.1 Ų37.14%0.03920%0.204CC..THydrogen-bonded Turntrans66.8-5.8-178.1-34.1-67.588.400115F38 S43 R44 F45 T54 K131 N250F38-M40 PolarHBondContact O-N 3.34Å; M40-S43 CarbonylContact C-O 3.55Å; M40-S43 WeakPolarHBondContact CA-O 3.39Å; M40-S43 WeakPolarHBondContact CE-OG 3.42Å; M40-S43 PolarHBondContact N-OG 2.63Å; M40-R44 WeakPolarHBondContact CE-O 3.49Å; M40-F45 HydrophobicContact CB-CD2 4.4Å; M40-F45 HydrophobicContact CG-CD2 4.2Å; M40-F45 HydrophobicContact SD-CB 4.34Å; M40-F45 HydrophobicContact SD-CD2 3.77Å; M40-F45 HydrophobicContact SD-CG 4.46Å; M40-T54 HydrophobicContact CE-CG2 3.79Å; M40-T54 HydrophobicContact SD-CG2 4.18Å; M40-K131 VanDerWaalsContact O-CE 3.25Å; M40-K131 WeakPolarHBondContact O-CE 3.35Å; M40-K131 PolarHBondContact O-NZ 2.99Å; M40-N250 PolarHBondContact O-ND2 2.77Å
41T98.8Very high97.8Very high0 Ų037.5 Ų37.50%019%0.188CC..THydrogen-bonded Turntrans-98-57.3170.7-67.80000112D37 F38 D39 K131 L224 G225 D226 Y248D37-T41 HydrophobicContact CB-CG2 4.39Å; F38-T41 PolarHBondContact O-N 3.39Å; D39-T41 PolarHBondContact O-N 3.02Å; T41-K131 WeakPolarHBondContact O-CD 3.06Å; T41-K131 WeakPolarHBondContact O-CE 3.5Å; T41-L224 HydrophobicContact CG2-CB 3.72Å; T41-G225 VanDerWaalsContact OG1-CA 3.31Å; T41-G225 WeakPolarHBondContact OG1-CA 3.4Å; T41-D226 WeakPolarHBondContact OG1-CB 3.35Å; T41-D226 PolarHBondContact OG1-N 3.2Å; T41-D226 VanDerWaalsContact OG1-N 3.08Å; T41-D226 PolarHBondContact OG1-OD1 3.42Å; T41-Y248 HydrophobicContact CG2-CD2 4.14Å; T41-Y248 HydrophobicContact CG2-CE2 4.25Å
42L98.9Very high97.7Very high1 Ų134.7 Ų34.71%0.00518%0.176CC..THydrogen-bonded Turntrans-94.6-32.7173-68.2175.6000111.3T36 D37 F38 L130 K131 F137 F138 I150 L274T36-L42 HydrophobicContact CG2-CD1 3.79Å; T36-L42 HydrophobicContact CG2-CG 4.43Å; D37-L42 WeakPolarHBondContact O-CG 3.28Å; F38-L42 HydrophobicContact CD2-CB 4.05Å; F38-L42 HydrophobicContact CD2-CD1 4Å; F38-L42 HydrophobicContact CE2-CB 4.41Å; F38-L42 PolarHBondContact O-N 3.2Å; L42-L130 WeakPolarHBondContact O-CA 3.47Å; L42-K131 PolarHBondContact O-N 3.42Å; L42-F137 HydrophobicContact CD2-CD1 4.47Å; L42-F137 HydrophobicContact CD2-CE1 4.07Å; L42-F138 HydrophobicContact CD1-CZ 4Å; L42-I150 HydrophobicContact CD1-CD1 4.06Å; L42-I150 HydrophobicContact CD1-CG1 4.36Å; L42-L274 HydrophobicContact CD2-CD1 4.22Å; L42-L274 HydrophobicContact CD2-CD2 4.26Å
43S98.8Very high97.7Very high0 Ų035.3 Ų35.30%018%0.18CC..BIsolated β-bridgetrans-84154.4167.169.50000111.4F38 D39 M40 M129F38-S43 PolarHBondContact O-N 3.37Å; F38-S43 PolarHBondContact O-OG 2.77Å; D39-S43 WeakPolarHBondContact CA-OG 3.39Å; M40-S43 CarbonylContact C-O 3.55Å; M40-S43 WeakPolarHBondContact CA-O 3.39Å; M40-S43 WeakPolarHBondContact CE-OG 3.42Å; M40-S43 PolarHBondContact N-OG 2.63Å; S43-M129 CarbonylContact C-O 3.54Å; S43-M129 VanDerWaalsContact CA-O 3.3Å; S43-M129 WeakPolarHBondContact CA-O 3.33Å; S43-M129 WeakPolarHBondContact CB-O 3.33Å
44R98.8Very high97.7Very high39 Ų3936.4 Ų36.415%0.14719%0.187CC..  trans-70.1149.7177.7-64.5-172.6-173.2-140.3-1.6110.7M40 C52 M129 L130 K131 E272M40-R44 WeakPolarHBondContact CE-O 3.49Å; R44-C52 HydrophobicContact CB-CB 4.42Å; R44-C52 VanDerWaalsContact O-CB 3.26Å; R44-C52 WeakPolarHBondContact O-CB 3.48Å; R44-M129 HydrophobicContact CB-CB 4.29Å; R44-M129 HydrophobicContact CG-CB 4.05Å; R44-M129 PolarHBondContact N-O 3.15Å; R44-L130 WeakPolarHBondContact CG-O 3.42Å; R44-L130 PolarHBondContact NE-O 3.07Å; R44-K131 HydrophobicContact CG-CG 4.21Å; R44-E272 WeakPolarHBondContact CA-OE2 3.33Å; R44-E272 WeakPolarHBondContact CB-OE2 3.47Å; R44-E272 HydrophobicContact CG-CB 4.33Å
45F98.2Very high97.7Very high30 Ų3036.4 Ų36.413%0.13219%0.187CC..SBendtrans-80.7-39.4169.7177.2-98.9000111.5M40 R51 C52 N250 D251 E272M40-F45 HydrophobicContact CB-CD2 4.4Å; M40-F45 HydrophobicContact CG-CD2 4.2Å; M40-F45 HydrophobicContact SD-CB 4.34Å; M40-F45 HydrophobicContact SD-CD2 3.77Å; M40-F45 HydrophobicContact SD-CG 4.46Å; F45-R51 WeakPolarHBondContact O-CA 3.28Å; F45-R51 WeakPolarHBondContact O-CG 3.45Å; F45-C52 PolarHBondContact O-N 2.88Å; F45-N250 HydrophobicContact CB-CB 3.76Å; F45-N250 HydrophobicContact CD1-CB 4.01Å; F45-N250 HydrophobicContact CD2-CB 3.55Å; F45-N250 HydrophobicContact CE1-CB 4.48Å; F45-N250 HydrophobicContact CE2-CB 4.06Å; F45-N250 HydrophobicContact CG-CB 3.51Å; F45-D251 HydrophobicContact CE2-CB 4.28Å; F45-D251 HydrophobicContact CZ-CB 3.81Å; F45-E272 WeakPolarHBondContact CA-OE1 3.34Å; F45-E272 WeakPolarHBondContact CB-OE1 3.47Å; F45-E272 PolarHBondContact N-OE1 3.02Å; F45-E272 VanDerWaalsContact N-OE1 3.09Å; F45-E272 PolarHBondContact N-OE2 3.17Å
46S96.8Very high97.7Very high39 Ų3937.2 Ų37.227%0.27319%0.191SC..EExtended strand (participates in β ladder)trans-148.9158.6179.770.10000113.1K50 E272S46-K50 CarbonylContact C-O 3.45Å; S46-K50 VanDerWaalsContact CA-O 3.24Å; S46-K50 WeakPolarHBondContact CA-O 3.37Å; S46-K50 WeakPolarHBondContact CB-O 3.48Å; S46-E272 PolarHBondContact N-OE1 3.21Å; S46-E272 PolarHBondContact OG-OE1 3.31Å
47Y97.6Very high97.6Very high94 Ų9438.2 Ų38.237%0.36920%0.196SC..EExtended strand (participates in β ladder)trans-143.6126.9172.8-175.6-110000110.1G49 K50 M129Y47-G49 PolarHBondContact O-N 3.29Å; Y47-K50 PolarHBondContact N-O 3.48Å; Y47-K50 PolarHBondContact O-N 2.7Å; Y47-M129 HydrophobicContact CD1-CE 4.36Å; Y47-M129 HydrophobicContact CD1-SD 3.55Å; Y47-M129 VanDerWaalsContact CD1-SD 3.55Å; Y47-M129 HydrophobicContact CD2-CE 4.05Å; Y47-M129 HydrophobicContact CD2-SD 3.67Å; Y47-M129 HydrophobicContact CE1-CE 4.28Å; Y47-M129 HydrophobicContact CE1-SD 4.05Å; Y47-M129 HydrophobicContact CE2-CE 3.96Å; Y47-M129 HydrophobicContact CE2-SD 4.15Å; Y47-M129 HydrophobicContact CG-CE 4.24Å; Y47-M129 HydrophobicContact CG-SD 3.34Å
48K95.3Very high97.6Very high179 Ų17938 Ų3878%0.77820%0.195SC*.THydrogen-bonded Turntrans50.241.4-179.2-64.2178.7174.9168.80113.5K50K48-K50 VanDerWaalsContact C-N 3.28Å; K48-K50 PolarHBondContact O-N 3.14Å
49G91.9Very high97.6Very high83 Ų8338 Ų3886%0.85620%0.195SC*.THydrogen-bonded Turntrans78.90.6178.400000115.3Y47Y47-G49 PolarHBondContact O-N 3.29Å
50K95.3Very high97.5Very high129 Ų12937.9 Ų37.956%0.56119%0.194SC*.EExtended strand (participates in β ladder)trans-104134.7172.6-173-174.1176.9-170.20109.7S46 Y47 K48 C52 D127S46-K50 CarbonylContact C-O 3.45Å; S46-K50 VanDerWaalsContact CA-O 3.24Å; S46-K50 WeakPolarHBondContact CA-O 3.37Å; S46-K50 WeakPolarHBondContact CB-O 3.48Å; Y47-K50 PolarHBondContact N-O 3.48Å; Y47-K50 PolarHBondContact O-N 2.7Å; K48-K50 VanDerWaalsContact C-N 3.28Å; K48-K50 PolarHBondContact O-N 3.14Å; K50-C52 PolarHBondContact O-N 3.46Å; K50-D127 IonicContact NZ-OD2 2.65Å; K50-D127 PolarHBondContact NZ-OD2 2.91Å
51R95.8Very high97.4Very high92 Ų9241.8 Ų41.835%0.34722%0.215SC..EExtended strand (participates in β ladder)trans-64.9130.3173.9-167.3175.7176.9-176.30.7110.2F45F45-R51 WeakPolarHBondContact O-CA 3.28Å; F45-R51 WeakPolarHBondContact O-CG 3.45Å
52C97.9Very high97.3Very high8 Ų842.4 Ų42.45%0.05422%0.219CC..PPolyproline II helixtrans-76.2152.7175.2-75.20000110.6R44 F45 K50R44-C52 HydrophobicContact CB-CB 4.42Å; R44-C52 VanDerWaalsContact O-CB 3.26Å; R44-C52 WeakPolarHBondContact O-CB 3.48Å; F45-C52 PolarHBondContact O-N 2.88Å; K50-C52 PolarHBondContact O-N 3.46Å
53P97.9Very high97.2Very high13 Ų1350.1 Ų50.18%0.08425%0.253CS..PPolyproline II helixtrans-76.6141-179.131.8-34.4000111.6N57 I58 D127 V128P53-N57 HydrophobicContact CB-CB 3.74Å; P53-I58 HydrophobicContact CB-CG1 4.07Å; P53-I58 HydrophobicContact CG-CG1 4.06Å; P53-D127 VanDerWaalsContact CD-O 3.31Å; P53-D127 WeakPolarHBondContact CD-O 3.28Å; P53-D127 HydrophobicContact CG-CB 4.37Å; P53-V128 HydrophobicContact CG-CB 4.22Å
54T98.3Very high97.1Very high24 Ų2453.4 Ų53.415%0.14727%0.27CS..PPolyproline II helixtrans-71.9170.6158.665.10000111D39 M40 H56 N57 I58D39-T54 HydrophobicContact CB-CG2 4.24Å; D39-T54 WeakPolarHBondContact OD1-CA 3.5Å; M40-T54 HydrophobicContact CE-CG2 3.79Å; M40-T54 HydrophobicContact SD-CG2 4.18Å; T54-H56 VanDerWaalsContact C-N 3.25Å; T54-H56 PolarHBondContact O-N 3.21Å; T54-H56 PolarHBondContact OG1-N 3.44Å; T54-N57 CarbonylContact O-C 3.58Å; T54-N57 WeakPolarHBondContact O-CA 3.48Å; T54-N57 PolarHBondContact O-N 3.37Å; T54-N57 PolarHBondContact OG1-N 2.98Å; T54-N57 VanDerWaalsContact OG1-N 3.17Å; T54-N57 PolarHBondContact OG1-OD1 2.85Å; T54-I58 WeakPolarHBondContact O-CG1 3.29Å; T54-I58 PolarHBondContact O-N 3.24Å
55C98.6Very high97.1Very high0 Ų051.8 Ų51.80%026%0.264CS..Hα-helixtrans-51.7-41.4171.4-76.80000113.3F38 D39 I155 V158F38-C55 WeakPolarHBondContact CE1-SG 3.35Å; D39-C55 PolarHBondContact OD1-N 2.83Å; D39-C55 PolarHBondContact OD2-N 2.83Å; C55-I155 HydrophobicContact CB-CB 4.31Å; C55-V158 HydrophobicContact CB-CB 4.33Å; C55-V158 HydrophobicContact CB-CG1 4.14Å
56H98.3Very high97.1Very high18 Ų1853.9 Ų53.98%0.08328%0.28CS..Hα-helixtrans-64.8-45.6172.5-73.275.2000111.6T54 I58 I59 D60 Y102 H106T54-H56 VanDerWaalsContact C-N 3.25Å; T54-H56 PolarHBondContact O-N 3.21Å; T54-H56 PolarHBondContact OG1-N 3.44Å; H56-I58 PolarHBondContact O-N 3.35Å; H56-I59 WeakPolarHBondContact O-CA 3.35Å; H56-I59 PolarHBondContact O-N 2.92Å; H56-D60 PolarHBondContact O-N 3.39Å; H56-Y102 AromaticContact CE1-CE1 3.68Å; H56-Y102 AromaticContact NE2-CE1 3.83Å; H56-H106 AromaticContact CE1-NE2 3.96Å; H56-H106 AromaticContact NE2-CD2 3.63Å; H56-H106 AromaticContact NE2-NE2 3.09Å; H56-H106 PolarHBondContact NE2-NE2 2.93Å
57N97.8Very high97.1Very high20 Ų2057.7 Ų57.711%0.10730%0.297CS..Hα-helixtrans-67.3-21.7-178.3-65.5162.2000113.4P53 T54 I59 D60 N61 K77P53-N57 HydrophobicContact CB-CB 3.74Å; T54-N57 CarbonylContact O-C 3.58Å; T54-N57 WeakPolarHBondContact O-CA 3.48Å; T54-N57 PolarHBondContact O-N 3.37Å; T54-N57 PolarHBondContact OG1-N 2.98Å; T54-N57 VanDerWaalsContact OG1-N 3.17Å; T54-N57 PolarHBondContact OG1-OD1 2.85Å; N57-I59 VanDerWaalsContact C-N 3.33Å; N57-D60 PolarHBondContact ND2-OD2 2.8Å; N57-N61 WeakPolarHBondContact O-CB 3.38Å; N57-N61 VanDerWaalsContact O-CG 3.3Å; N57-N61 PolarHBondContact O-N 2.83Å; N57-N61 PolarHBondContact O-ND2 3.24Å; N57-K77 PolarHBondContact OD1-NZ 2.79Å
58I98.7Very high97.1Very high4 Ų459.1 Ų59.12%0.02131%0.307CS..Hα-helixtrans-61-45.4168.5-69.3169.8000110P53 T54 H56 C62 I122 V123 V128 V158 V162P53-I58 HydrophobicContact CB-CG1 4.07Å; P53-I58 HydrophobicContact CG-CG1 4.06Å; T54-I58 WeakPolarHBondContact O-CG1 3.29Å; T54-I58 PolarHBondContact O-N 3.24Å; H56-I58 PolarHBondContact O-N 3.35Å; I58-C62 PolarHBondContact O-N 2.95Å; I58-I122 HydrophobicContact CG2-CG2 3.77Å; I58-V123 HydrophobicContact CG2-CG2 4.19Å; I58-V128 HydrophobicContact CD1-CB 3.75Å; I58-V128 HydrophobicContact CD1-CG1 4.24Å; I58-V128 HydrophobicContact CD1-CG2 3.85Å; I58-V128 HydrophobicContact CG1-CB 4.28Å; I58-V158 HydrophobicContact CB-CG1 4.04Å; I58-V158 HydrophobicContact CD1-CG1 3.68Å; I58-V158 HydrophobicContact CG1-CG1 4.46Å; I58-V158 HydrophobicContact CG2-CG1 3.99Å; I58-V162 HydrophobicContact CD1-CG2 3.86Å
59I98.3Very high97.2Very high0 Ų050.8 Ų50.80%027%0.271CS..Hα-helixtrans-72-50.4177.3-58.4-56.8000111.1H56 N57 N61 C62 V65 L109 L114 L119 I122 I155 V158 M180H56-I59 WeakPolarHBondContact O-CA 3.35Å; H56-I59 PolarHBondContact O-N 2.92Å; N57-I59 VanDerWaalsContact C-N 3.33Å; I59-N61 PolarHBondContact O-N 3.15Å; I59-C62 PolarHBondContact O-N 3.46Å; I59-C62 PolarHBondContact O-SG 3.18Å; I59-V65 HydrophobicContact CG2-CG2 4.24Å; I59-V65 WeakPolarHBondContact O-CG2 3.35Å; I59-L109 HydrophobicContact CB-CD1 4.48Å; I59-L109 HydrophobicContact CG2-CD1 4.04Å; I59-L109 HydrophobicContact CG2-CD2 3.73Å; I59-L109 HydrophobicContact CG2-CG 4.42Å; I59-L114 HydrophobicContact CG2-CD1 3.36Å; I59-L119 HydrophobicContact CD1-CD2 3.87Å; I59-I122 HydrophobicContact CD1-CG2 4.06Å; I59-I155 HydrophobicContact CG1-CD1 3.94Å; I59-V158 HydrophobicContact CD1-CG2 3.62Å; I59-V158 HydrophobicContact CG1-CG2 3.77Å; I59-M180 HydrophobicContact CD1-CE 4.45Å; I59-M180 HydrophobicContact CG1-CE 4.25Å
60D96.8Very high97.5Very high15 Ų1550 Ų508%0.0824%0.243CC..Hα-helixtrans-51.8-35.9-179.6-56.4-23.3000111H56 N57 R70 L73H56-D60 PolarHBondContact O-N 3.39Å; N57-D60 PolarHBondContact ND2-OD2 2.8Å; D60-R70 VanDerWaalsContact O-CZ 3.3Å; D60-R70 PolarHBondContact O-NH2 2.58Å; D60-L73 HydrophobicContact CB-CD1 4.15Å
61N95.8Very high97.6Very high90 Ų9050.5 Ų50.548%0.48125%0.245SC..Hα-helixtrans-90.5-8.8-176.3-67.2-49000115.5N57 I59 R70N57-N61 WeakPolarHBondContact O-CB 3.38Å; N57-N61 VanDerWaalsContact O-CG 3.3Å; N57-N61 PolarHBondContact O-N 2.83Å; N57-N61 PolarHBondContact O-ND2 3.24Å; I59-N61 PolarHBondContact O-N 3.15Å; N61-R70 PolarHBondContact O-NH1 3.09Å; N61-R70 PolarHBondContact O-NH2 2.86Å; N61-R70 PolarHBondContact OD1-NH1 3.32Å
62C97.2Very high97.7Very high12 Ų1250 Ų508%0.08125%0.245CC..SBendtrans-71.5164.9-173.883.10000112.9I58 I59 L64 V65 R70 I122I58-C62 PolarHBondContact O-N 2.95Å; I59-C62 PolarHBondContact O-N 3.46Å; I59-C62 PolarHBondContact O-SG 3.18Å; C62-L64 PolarHBondContact O-N 3.28Å; C62-L64 PolarHBondContact SG-N 3.48Å; C62-V65 PolarHBondContact O-N 3.26Å; C62-R70 PolarHBondContact O-NH2 2.86Å; C62-I122 HydrophobicContact CB-CB 4.33Å; C62-I122 HydrophobicContact CB-CD1 4.42Å; C62-I122 HydrophobicContact CB-CG1 3.99Å; C62-I122 HydrophobicContact CB-CG2 3.54Å
63K96.8Very high97.7Very high163 Ų16350 Ų5071%0.70924%0.244SC*.THydrogen-bonded Turntrans-66.7-16.7-178.4-64.9171.7-176.21580114E125K63-E125 WeakPolarHBondContact CE-OE2 3.3Å; K63-E125 IonicContact NZ-OE1 3.34Å; K63-E125 PolarHBondContact NZ-OE1 3.34Å; K63-E125 IonicContact NZ-OE2 3.01Å; K63-E125 PolarHBondContact NZ-OE2 2.72Å
64L97.3Very high97.5Very high70 Ų7053.8 Ų53.837%0.36626%0.264SS..THydrogen-bonded Turntrans-85.4-14.1179.9-56.2-173.5000113C62 L114 P115 K118 I122C62-L64 PolarHBondContact O-N 3.28Å; C62-L64 PolarHBondContact SG-N 3.48Å; L64-L114 HydrophobicContact CB-CD2 3.77Å; L64-L114 HydrophobicContact CD1-CD2 4.33Å; L64-P115 HydrophobicContact CD1-CG 4.04Å; L64-K118 HydrophobicContact CD1-CB 3.94Å; L64-K118 HydrophobicContact CD1-CG 4.23Å; L64-I122 HydrophobicContact CD1-CD1 3.91Å; L64-I122 HydrophobicContact CG-CD1 4.48Å
65V97.9Very high97.5Very high4 Ų458.7 Ų58.72%0.02429%0.285CS..SBendtrans-94.3117.1175.9177.90000109.3I59 C62 C69 R70 L73 Q112 L114I59-V65 HydrophobicContact CG2-CG2 4.24Å; I59-V65 WeakPolarHBondContact O-CG2 3.35Å; C62-V65 PolarHBondContact O-N 3.26Å; V65-C69 HydrophobicContact CG1-CB 3.84Å; V65-R70 HydrophobicContact CG1-CB 4.46Å; V65-R70 PolarHBondContact O-NH2 3.44Å; V65-R70 VanDerWaalsContact O-NH2 3.08Å; V65-L73 HydrophobicContact CG1-CD1 4.12Å; V65-Q112 HydrophobicContact CG1-CG 4.41Å; V65-Q112 HydrophobicContact CG2-CG 4.27Å; V65-L114 HydrophobicContact CG2-CD2 4.39Å
66T98.1Very high97.4Very high75 Ų7559.9 Ų59.946%0.4629%0.291SS..  trans-59.5151.7177.959.20000112.1E68 C69 R70 Q112T66-E68 PolarHBondContact O-N 2.9Å; T66-C69 PolarHBondContact O-N 2.9Å; T66-C69 VanDerWaalsContact O-N 3.1Å; T66-C69 VanDerWaalsContact OG1-CB 3.29Å; T66-C69 WeakPolarHBondContact OG1-CB 3.44Å; T66-C69 PolarHBondContact OG1-N 2.78Å; T66-R70 PolarHBondContact O-N 3.4Å; T66-Q112 PolarHBondContact OG1-OE1 2.87Å
67D97.6Very high97.2Very high118 Ų11861.2 Ų61.263%0.63130%0.297SS*.Hα-helixtrans-59.5-33177.1-70.3-21.3000112.8R70 K71D67-R70 PolarHBondContact O-N 3.39Å; D67-K71 VanDerWaalsContact O-CG 3.32Å; D67-K71 WeakPolarHBondContact O-CG 3.47Å; D67-K71 PolarHBondContact O-N 2.78Å
68E97.9Very high97Very high124 Ų12466.2 Ų66.258%0.57932%0.32SS*.Hα-helixtrans-65.5-46.2175.1-167.8-166.3147.600111.3T66 R70 K71 K72T66-E68 PolarHBondContact O-N 2.9Å; E68-R70 VanDerWaalsContact C-N 3.33Å; E68-R70 PolarHBondContact O-N 2.83Å; E68-K71 PolarHBondContact O-N 2.85Å; E68-K72 PolarHBondContact O-N 3.39Å; E68-K72 VanDerWaalsContact O-N 3.15Å; E68-K72 VanDerWaalsContact OE1-CE 3.27Å; E68-K72 WeakPolarHBondContact OE1-CE 3.31Å; E68-K72 IonicContact OE1-NZ 3.13Å; E68-K72 PolarHBondContact OE1-NZ 3.36Å
69C97.9Very high96.8Very high4 Ų471.1 Ų71.13%0.02734%0.341CS..Hα-helixtrans-62.7-42.6176.3-173.20000111V65 T66 K71 K72 L73 Q112V65-C69 HydrophobicContact CG1-CB 3.84Å; T66-C69 PolarHBondContact O-N 2.9Å; T66-C69 VanDerWaalsContact O-N 3.1Å; T66-C69 VanDerWaalsContact OG1-CB 3.29Å; T66-C69 WeakPolarHBondContact OG1-CB 3.44Å; T66-C69 PolarHBondContact OG1-N 2.78Å; C69-K71 VanDerWaalsContact C-N 3.31Å; C69-K71 PolarHBondContact O-N 3.01Å; C69-K72 WeakPolarHBondContact O-CB 3.38Å; C69-K72 PolarHBondContact O-N 3.1Å; C69-L73 WeakPolarHBondContact O-CG 3.42Å; C69-L73 PolarHBondContact O-N 2.82Å; C69-Q112 HydrophobicContact CB-CG 4.25Å
70R97.6Very high96.7Very high66 Ų6671.1 Ų71.125%0.24934%0.341CS..Hα-helixtrans-58.9-40.4176.5-164.7-178.9-50.6-120-16.4112.7D60 N61 C62 V65 T66 D67 E68 L73 L74D60-R70 VanDerWaalsContact O-CZ 3.3Å; D60-R70 PolarHBondContact O-NH2 2.58Å; N61-R70 PolarHBondContact O-NH1 3.09Å; N61-R70 PolarHBondContact O-NH2 2.86Å; N61-R70 PolarHBondContact OD1-NH1 3.32Å; C62-R70 PolarHBondContact O-NH2 2.86Å; V65-R70 HydrophobicContact CG1-CB 4.46Å; V65-R70 PolarHBondContact O-NH2 3.44Å; V65-R70 VanDerWaalsContact O-NH2 3.08Å; T66-R70 PolarHBondContact O-N 3.4Å; D67-R70 PolarHBondContact O-N 3.39Å; E68-R70 VanDerWaalsContact C-N 3.33Å; E68-R70 PolarHBondContact O-N 2.83Å; R70-L73 PolarHBondContact O-N 2.84Å; R70-L74 WeakPolarHBondContact O-CB 3.47Å; R70-L74 PolarHBondContact O-N 2.9Å
71K97.4Very high96.4Very high141 Ų14173 Ų7361%0.61335%0.347SS*.Hα-helixtrans-62-43.2173.2-74.3170.9-176.3176.50111.8D67 E68 C69 L74 Q75D67-K71 VanDerWaalsContact O-CG 3.32Å; D67-K71 WeakPolarHBondContact O-CG 3.47Å; D67-K71 PolarHBondContact O-N 2.78Å; E68-K71 PolarHBondContact O-N 2.85Å; C69-K71 VanDerWaalsContact C-N 3.31Å; C69-K71 PolarHBondContact O-N 3.01Å; K71-L74 PolarHBondContact O-N 2.8Å; K71-Q75 VanDerWaalsContact O-CG 3.29Å; K71-Q75 WeakPolarHBondContact O-CG 3.42Å; K71-Q75 PolarHBondContact O-N 3.42Å
72K98.1Very high96.2Very high80 Ų8071.3 Ų71.335%0.34835%0.346SS..Hα-helixtrans-63.7-44176.3-66.9173.3-173.61670111.4E68 C69 Q75 L76 L108E68-K72 PolarHBondContact O-N 3.39Å; E68-K72 VanDerWaalsContact O-N 3.15Å; E68-K72 VanDerWaalsContact OE1-CE 3.27Å; E68-K72 WeakPolarHBondContact OE1-CE 3.31Å; E68-K72 IonicContact OE1-NZ 3.13Å; E68-K72 PolarHBondContact OE1-NZ 3.36Å; C69-K72 WeakPolarHBondContact O-CB 3.38Å; C69-K72 PolarHBondContact O-N 3.1Å; K72-Q75 PolarHBondContact O-N 3.46Å; K72-L76 WeakPolarHBondContact O-CG 3.39Å; K72-L76 PolarHBondContact O-N 2.82Å; K72-L108 HydrophobicContact CB-CD1 3.76Å; K72-L108 HydrophobicContact CD-CD2 4.12Å
73L97.3Very high96Very high8 Ų872 Ų724%0.04235%0.349CS..Hα-helixtrans-62.3-42.2176.7-71.4162.8000111.8D60 V65 C69 R70 L76 K77 L108 L109D60-L73 HydrophobicContact CB-CD1 4.15Å; V65-L73 HydrophobicContact CG1-CD1 4.12Å; C69-L73 WeakPolarHBondContact O-CG 3.42Å; C69-L73 PolarHBondContact O-N 2.82Å; R70-L73 PolarHBondContact O-N 2.84Å; L73-L76 PolarHBondContact O-N 3.02Å; L73-K77 PolarHBondContact O-N 2.91Å; L73-L108 HydrophobicContact CD2-CB 4.14Å; L73-L108 HydrophobicContact CD2-CD1 3.92Å; L73-L108 HydrophobicContact CG-CD1 4.05Å; L73-L109 HydrophobicContact CD1-CD2 4Å; L73-L109 HydrophobicContact CD2-CD2 4.47Å
74L94.7Very high95.7Very high94 Ų9466.3 Ų66.349%0.49232%0.324SS..Hα-helixtrans-62.7-45.1175.2-17861.9000111.7R70 K71 L76 K77 E78R70-L74 WeakPolarHBondContact O-CB 3.47Å; R70-L74 PolarHBondContact O-N 2.9Å; K71-L74 PolarHBondContact O-N 2.8Å; L74-L76 VanDerWaalsContact C-N 3.32Å; L74-L76 PolarHBondContact O-N 3.33Å; L74-K77 WeakPolarHBondContact O-CB 3.42Å; L74-K77 PolarHBondContact O-N 2.84Å; L74-K77 VanDerWaalsContact O-N 3.14Å; L74-E78 HydrophobicContact CD1-CG 4.41Å; L74-E78 WeakPolarHBondContact O-CG 3.47Å; L74-E78 PolarHBondContact O-N 3.36Å
75Q96.9Very high95Very high126 Ų12664 Ų6459%0.58931%0.313SS*.Hα-helixtrans-61-39.8175.9-73.6171.2-8.400112.4K71 K72 K79K71-Q75 VanDerWaalsContact O-CG 3.29Å; K71-Q75 WeakPolarHBondContact O-CG 3.42Å; K71-Q75 PolarHBondContact O-N 3.42Å; K72-Q75 PolarHBondContact O-N 3.46Å; Q75-K79 WeakPolarHBondContact O-CB 3.36Å; Q75-K79 PolarHBondContact O-N 3.07Å; Q75-K79 VanDerWaalsContact O-N 3.16Å
76L97.3Very high94.4Very high25 Ų2566.2 Ų66.213%0.13133%0.325CS..Hα-helixtrans-61.6-49.2172.4-69.3174.7000110.3K72 L73 L74 E78 K79 Y80 K104 L108K72-L76 WeakPolarHBondContact O-CG 3.39Å; K72-L76 PolarHBondContact O-N 2.82Å; L73-L76 PolarHBondContact O-N 3.02Å; L74-L76 VanDerWaalsContact C-N 3.32Å; L74-L76 PolarHBondContact O-N 3.33Å; L76-E78 PolarHBondContact O-N 3.32Å; L76-K79 PolarHBondContact O-N 2.71Å; L76-Y80 HydrophobicContact CB-CD2 4.29Å; L76-Y80 HydrophobicContact CD2-CD2 4.22Å; L76-Y80 HydrophobicContact CD2-CE2 3.69Å; L76-Y80 WeakPolarHBondContact O-CD2 3.33Å; L76-Y80 PolarHBondContact O-N 2.77Å; L76-K104 HydrophobicContact CD1-CB 3.77Å; L76-K104 HydrophobicContact CD2-CB 4.04Å; L76-K104 HydrophobicContact CD2-CD 3.74Å; L76-L108 HydrophobicContact CD1-CD1 3.63Å
77K94Very high93.6Very high46 Ų4667.5 Ų67.520%0.233%0.334CS..Hα-helixtrans-57.1-50.1178.9-179.8177.6-180173.80111.6N57 L73 L74 K79 Y80 Y81 W101N57-K77 PolarHBondContact OD1-NZ 2.79Å; L73-K77 PolarHBondContact O-N 2.91Å; L74-K77 WeakPolarHBondContact O-CB 3.42Å; L74-K77 PolarHBondContact O-N 2.84Å; L74-K77 VanDerWaalsContact O-N 3.14Å; K77-K79 VanDerWaalsContact C-N 3.31Å; K77-K79 PolarHBondContact O-N 2.85Å; K77-Y80 PolarHBondContact O-N 2.97Å; K77-Y81 WeakPolarHBondContact O-CA 3.41Å; K77-Y81 WeakPolarHBondContact O-CB 3.29Å; K77-Y81 PolarHBondContact O-N 3.09Å; K77-W101 HydrophobicContact CB-CZ2 4.07Å; K77-W101 HydrophobicContact CG-CZ2 4.05Å
78E92.9Very high93.2Very high126 Ų12667.8 Ų67.859%0.58934%0.34SS*.Hα-helixtrans-56.9-44.2179.3-72.7175166.500112L74 L76 A82L74-E78 HydrophobicContact CD1-CG 4.41Å; L74-E78 WeakPolarHBondContact O-CG 3.47Å; L74-E78 PolarHBondContact O-N 3.36Å; L76-E78 PolarHBondContact O-N 3.32Å; E78-A82 WeakPolarHBondContact O-CB 3.22Å
79K95.8Very high92.8Very high106 Ų10664.3 Ų64.346%0.46133%0.325SS..Hα-helixtrans-66.5-54.4178.2-179.3-174.5175.9-167.90112.5Q75 L76 K77Q75-K79 WeakPolarHBondContact O-CB 3.36Å; Q75-K79 PolarHBondContact O-N 3.07Å; Q75-K79 VanDerWaalsContact O-N 3.16Å; L76-K79 PolarHBondContact O-N 2.71Å; K77-K79 VanDerWaalsContact C-N 3.31Å; K77-K79 PolarHBondContact O-N 2.85Å
80Y96.1Very high92.4Very high0 Ų067.2 Ų67.20%034%0.343CS..Hα-helixtrans-83.4-31.1-168.1-72-76.5000112.9L76 K77 A82 I83 E84 Y97 E100 W101 K104L76-Y80 HydrophobicContact CB-CD2 4.29Å; L76-Y80 HydrophobicContact CD2-CD2 4.22Å; L76-Y80 HydrophobicContact CD2-CE2 3.69Å; L76-Y80 WeakPolarHBondContact O-CD2 3.33Å; L76-Y80 PolarHBondContact O-N 2.77Å; K77-Y80 PolarHBondContact O-N 2.97Å; Y80-A82 VanDerWaalsContact C-N 3.29Å; Y80-A82 PolarHBondContact O-N 3.45Å; Y80-I83 HydrophobicContact CD1-CD1 4.35Å; Y80-I83 WeakPolarHBondContact O-CB 3.34Å; Y80-I83 PolarHBondContact O-N 3.45Å; Y80-I83 VanDerWaalsContact O-N 3.09Å; Y80-E84 PolarHBondContact O-N 2.95Å; Y80-Y97 VanDerWaalsContact CD1-O 3.29Å; Y80-Y97 WeakPolarHBondContact CD1-O 3.48Å; Y80-Y97 HydrophobicContact CE1-CD1 4.23Å; Y80-Y97 WeakPolarHBondContact CE1-O 3.38Å; Y80-E100 HydrophobicContact CE1-CB 4.14Å; Y80-E100 HydrophobicContact CE1-CG 4.35Å; Y80-E100 WeakPolarHBondContact CE1-OE2 3.38Å; Y80-E100 WeakPolarHBondContact OH-CG 3.44Å; Y80-E100 PolarHBondContact OH-OE1 3.16Å; Y80-E100 VanDerWaalsContact OH-OE1 3.06Å; Y80-E100 PolarHBondContact OH-OE2 2.98Å; Y80-W101 HydrophobicContact CD1-CB 3.71Å; Y80-W101 HydrophobicContact CD1-CG 4.31Å; Y80-W101 HydrophobicContact CD2-CB 3.67Å; Y80-W101 AromaticContact CD2-CD1 3.57Å; Y80-W101 HydrophobicContact CD2-CD2 4.4Å; Y80-W101 AromaticContact CD2-CG 3.6Å; Y80-W101 HydrophobicContact CD2-CG 3.6Å; Y80-W101 HydrophobicContact CE1-CB 4.27Å; Y80-W101 HydrophobicContact CE2-CB 4.29Å; Y80-W101 HydrophobicContact CG-CB 3.4Å; Y80-W101 AromaticContact CG-CD1 3.96Å; Y80-W101 HydrophobicContact CG-CD2 4.05Å; Y80-W101 AromaticContact CG-CG 3.51Å; Y80-W101 HydrophobicContact CG-CG 3.51Å; Y80-K104 HydrophobicContact CE2-CD 4.43Å; Y80-K104 PolarHBondContact OH-NZ 2.95Å
81Y90.9Very high92.1Very high55 Ų5567 Ų6722%0.21635%0.349CS..Hα-helixtrans-61.8-41.5172.9-173-114000110.5K77 I83 E84 V85 W101K77-Y81 WeakPolarHBondContact O-CA 3.41Å; K77-Y81 WeakPolarHBondContact O-CB 3.29Å; K77-Y81 PolarHBondContact O-N 3.09Å; Y81-I83 PolarHBondContact O-N 3.44Å; Y81-E84 WeakPolarHBondContact CD2-OE2 3.25Å; Y81-E84 WeakPolarHBondContact O-CB 3.44Å; Y81-E84 PolarHBondContact O-N 3.32Å; Y81-V85 HydrophobicContact CD1-CG1 4.16Å; Y81-V85 HydrophobicContact CD2-CG1 3.94Å; Y81-V85 HydrophobicContact CE1-CG1 3.79Å; Y81-V85 HydrophobicContact CE2-CG1 3.54Å; Y81-V85 HydrophobicContact CG-CG1 4.23Å; Y81-V85 VanDerWaalsContact CZ-CG1 3.45Å; Y81-V85 WeakPolarHBondContact O-CB 3.41Å; Y81-V85 WeakPolarHBondContact O-CG1 3.3Å; Y81-V85 WeakPolarHBondContact O-CG2 3.37Å; Y81-V85 PolarHBondContact O-N 3.31Å; Y81-W101 HydrophobicContact CD2-CH2 4.49Å
82A90.3Very high91.8Very high55 Ų5567 Ų6746%0.45535%0.351SS..Hα-helixtrans-57.1-29.9174.400000113.4E78 Y80 V85 D86E78-A82 WeakPolarHBondContact O-CB 3.22Å; Y80-A82 VanDerWaalsContact C-N 3.29Å; Y80-A82 PolarHBondContact O-N 3.45Å; A82-V85 WeakPolarHBondContact O-CG2 3.43Å; A82-D86 PolarHBondContact O-N 3.1Å
83I93.3Very high91.7Very high27 Ų2767.8 Ų67.814%0.13836%0.356CS..Hα-helixtrans-82.2-44.8175.9-62169.2000111Y80 Y81 V85 D86 L89 K94 Y97Y80-I83 HydrophobicContact CD1-CD1 4.35Å; Y80-I83 WeakPolarHBondContact O-CB 3.34Å; Y80-I83 PolarHBondContact O-N 3.45Å; Y80-I83 VanDerWaalsContact O-N 3.09Å; Y81-I83 PolarHBondContact O-N 3.44Å; I83-V85 PolarHBondContact O-N 3.4Å; I83-D86 WeakPolarHBondContact O-CB 3.39Å; I83-D86 PolarHBondContact O-N 3.3Å; I83-L89 HydrophobicContact CG2-CD1 3.82Å; I83-K94 HydrophobicContact CG2-CG 4.27Å; I83-K94 WeakPolarHBondContact O-CD 3.46Å; I83-K94 WeakPolarHBondContact O-CE 3.42Å; I83-Y97 HydrophobicContact CD1-CD1 3.7Å; I83-Y97 HydrophobicContact CD1-CE1 4.07Å; I83-Y97 HydrophobicContact CD1-CG 4.02Å; I83-Y97 HydrophobicContact CG2-CD2 3.84Å; I83-Y97 HydrophobicContact CG2-CG 3.88Å
84E90.1Very high91.5Very high43 Ų4368.3 Ų68.320%0.20136%0.358CS..Hα-helixtrans-52.4-43176.4-175.5-170.3161.900110.9Y80 Y81 K94 M98 W101 V198 F199Y80-E84 PolarHBondContact O-N 2.95Å; Y81-E84 WeakPolarHBondContact CD2-OE2 3.25Å; Y81-E84 WeakPolarHBondContact O-CB 3.44Å; Y81-E84 PolarHBondContact O-N 3.32Å; E84-K94 PolarHBondContact O-NZ 2.65Å; E84-M98 HydrophobicContact CB-CE 3.84Å; E84-M98 HydrophobicContact CB-SD 3.9Å; E84-M98 HydrophobicContact CG-SD 3.97Å; E84-W101 VanDerWaalsContact OE2-CZ3 3.29Å; E84-W101 WeakPolarHBondContact OE2-CZ3 3.35Å; E84-V198 HydrophobicContact CG-CG1 4.12Å; E84-F199 HydrophobicContact CG-CE2 4.32Å; E84-F199 HydrophobicContact CG-CZ 4.07Å
85V83.9Confident91.6Very high22 Ų2267.7 Ų67.713%0.13335%0.349CS..Hα-helixtrans-84.3-16.2-174.6-670000114.1Y81 A82 I83 R252Y81-V85 HydrophobicContact CD1-CG1 4.16Å; Y81-V85 HydrophobicContact CD2-CG1 3.94Å; Y81-V85 HydrophobicContact CE1-CG1 3.79Å; Y81-V85 HydrophobicContact CE2-CG1 3.54Å; Y81-V85 HydrophobicContact CG-CG1 4.23Å; Y81-V85 VanDerWaalsContact CZ-CG1 3.45Å; Y81-V85 WeakPolarHBondContact O-CB 3.41Å; Y81-V85 WeakPolarHBondContact O-CG1 3.3Å; Y81-V85 WeakPolarHBondContact O-CG2 3.37Å; Y81-V85 PolarHBondContact O-N 3.31Å; A82-V85 WeakPolarHBondContact O-CG2 3.43Å; I83-V85 PolarHBondContact O-N 3.4Å; V85-R252 VanDerWaalsContact CA-NH2 3.28Å; V85-R252 VanDerWaalsContact CG1-NH2 3.27Å; V85-R252 PolarHBondContact O-NH1 3.02Å; V85-R252 PolarHBondContact O-NH2 3.25Å
86D84.9Confident91.6Very high50 Ų5065.3 Ų65.327%0.26735%0.345SS..  trans-55.9118.5-172.7-167.6-40000112.4A82 I83 V88 L89 K94A82-D86 PolarHBondContact O-N 3.1Å; I83-D86 WeakPolarHBondContact O-CB 3.39Å; I83-D86 PolarHBondContact O-N 3.3Å; D86-V88 PolarHBondContact O-N 3.31Å; D86-V88 WeakPolarHBondContact OD1-CA 3.38Å; D86-V88 VanDerWaalsContact OD1-CB 3.24Å; D86-V88 WeakPolarHBondContact OD1-CB 3.16Å; D86-V88 PolarHBondContact OD1-N 3.22Å; D86-L89 HydrophobicContact CB-CB 4.36Å; D86-L89 HydrophobicContact CB-CD1 4.1Å; D86-L89 HydrophobicContact CB-CG 4.22Å; D86-L89 PolarHBondContact OD1-N 3.3Å; D86-K94 WeakPolarHBondContact O-CE 3.24Å; D86-K94 PolarHBondContact O-NZ 2.95Å
87P81.3Confident91.6Very high102 Ų10268.8 Ų68.866%0.66236%0.357SS*.SBendtrans-72.9-15.8-178.730.6-35.3000113.8
88V87.7Confident91.8Very high124 Ų12466.6 Ų66.675%0.75235%0.348SS*.SBendtrans-82.2-40.7-178.1-176.80000111.2D86D86-V88 PolarHBondContact O-N 3.31Å; D86-V88 WeakPolarHBondContact OD1-CA 3.38Å; D86-V88 VanDerWaalsContact OD1-CB 3.24Å; D86-V88 WeakPolarHBondContact OD1-CB 3.16Å; D86-V88 PolarHBondContact OD1-N 3.22Å
89L90.2Very high92Very high51 Ų5163 Ų6327%0.26733%0.334SS..SBendtrans-74.7139.4-177.2-64.1176.3000112.1I83 D86 E93 K94I83-L89 HydrophobicContact CG2-CD1 3.82Å; D86-L89 HydrophobicContact CB-CB 4.36Å; D86-L89 HydrophobicContact CB-CD1 4.1Å; D86-L89 HydrophobicContact CB-CG 4.22Å; D86-L89 PolarHBondContact OD1-N 3.3Å; L89-E93 WeakPolarHBondContact CA-OE2 3.34Å; L89-E93 HydrophobicContact CB-CB 4.42Å; L89-E93 HydrophobicContact CD2-CB 4.34Å; L89-K94 HydrophobicContact CB-CD 4.36Å; L89-K94 HydrophobicContact CB-CG 3.83Å; L89-K94 HydrophobicContact CD1-CG 4.33Å; L89-K94 VanDerWaalsContact O-CE 3.27Å; L89-K94 WeakPolarHBondContact O-CE 3.44Å
90T90.8Very high92.1Very high65 Ų6561.4 Ų61.440%0.39933%0.329SS..  trans-74.2167.5172.885.10000111.6E92 E93 K94T90-E92 VanDerWaalsContact C-N 3.26Å; T90-E92 WeakPolarHBondContact CB-OE2 2.95Å; T90-E92 PolarHBondContact O-N 3.08Å; T90-E92 PolarHBondContact OG1-N 3.38Å; T90-E92 PolarHBondContact OG1-OE2 3.39Å; T90-E93 PolarHBondContact N-OE2 2.77Å; T90-E93 PolarHBondContact O-N 2.82Å; T90-E93 PolarHBondContact OG1-N 2.89Å; T90-K94 VanDerWaalsContact O-CG 3.26Å; T90-K94 WeakPolarHBondContact O-CG 3.35Å; T90-K94 PolarHBondContact O-N 2.83Å; T90-K94 VanDerWaalsContact O-N 3.07Å
91V89.4Confident92.2Very high61 Ų6163 Ų6337%0.3734%0.335SS..Hα-helixtrans-62.5-38.8176.81740000110.8K94 Y95 F199V91-K94 PolarHBondContact O-N 3.36Å; V91-Y95 PolarHBondContact O-N 3.19Å; V91-F199 HydrophobicContact CG1-CB 3.79Å; V91-F199 HydrophobicContact CG1-CD1 3.84Å; V91-F199 HydrophobicContact CG1-CG 3.83Å; V91-F199 HydrophobicContact CG2-CD1 4.42Å
92E92.3Very high92.6Very high140 Ų14061.9 Ų61.965%0.65433%0.33SS*.Hα-helixtrans-65.3-40.8179.2-58.370.5-151.700111.4T90 Y95 P96T90-E92 VanDerWaalsContact C-N 3.26Å; T90-E92 WeakPolarHBondContact CB-OE2 2.95Å; T90-E92 PolarHBondContact O-N 3.08Å; T90-E92 PolarHBondContact OG1-N 3.38Å; T90-E92 PolarHBondContact OG1-OE2 3.39Å; E92-Y95 WeakPolarHBondContact O-CB 3.27Å; E92-Y95 PolarHBondContact O-N 3.36Å; E92-P96 WeakPolarHBondContact O-CD 3.13Å
93E95.1Very high92.9Very high98 Ų9863.3 Ų63.346%0.45833%0.334SS..Hα-helixtrans-68-36176.4-68175.7139.200112.1L89 T90 P96 Y97L89-E93 WeakPolarHBondContact CA-OE2 3.34Å; L89-E93 HydrophobicContact CB-CB 4.42Å; L89-E93 HydrophobicContact CD2-CB 4.34Å; T90-E93 PolarHBondContact N-OE2 2.77Å; T90-E93 PolarHBondContact O-N 2.82Å; T90-E93 PolarHBondContact OG1-N 2.89Å; E93-P96 WeakPolarHBondContact O-CD 3.15Å; E93-Y97 VanDerWaalsContact O-CD2 3.25Å; E93-Y97 WeakPolarHBondContact O-CD2 3.09Å; E93-Y97 WeakPolarHBondContact O-CE2 3.21Å
94K94.8Very high93.2Very high18 Ų1866 Ų668%0.07834%0.344CS..Hα-helixtrans-75.5-25.8177.8-68.2173.9-176.4-174.60113.6I83 E84 D86 L89 T90 V91 Y97 M98 F199I83-K94 HydrophobicContact CG2-CG 4.27Å; I83-K94 WeakPolarHBondContact O-CD 3.46Å; I83-K94 WeakPolarHBondContact O-CE 3.42Å; E84-K94 PolarHBondContact O-NZ 2.65Å; D86-K94 WeakPolarHBondContact O-CE 3.24Å; D86-K94 PolarHBondContact O-NZ 2.95Å; L89-K94 HydrophobicContact CB-CD 4.36Å; L89-K94 HydrophobicContact CB-CG 3.83Å; L89-K94 HydrophobicContact CD1-CG 4.33Å; L89-K94 VanDerWaalsContact O-CE 3.27Å; L89-K94 WeakPolarHBondContact O-CE 3.44Å; T90-K94 VanDerWaalsContact O-CG 3.26Å; T90-K94 WeakPolarHBondContact O-CG 3.35Å; T90-K94 PolarHBondContact O-N 2.83Å; T90-K94 VanDerWaalsContact O-N 3.07Å; V91-K94 PolarHBondContact O-N 3.36Å; K94-Y97 WeakPolarHBondContact O-CB 3.48Å; K94-Y97 PolarHBondContact O-N 3.46Å; K94-Y97 VanDerWaalsContact O-N 3.1Å; K94-M98 PolarHBondContact O-N 3.47Å; K94-M98 VanDerWaalsContact O-N 3.09Å; K94-F199 HydrophobicContact CB-CD2 3.95Å; K94-F199 HydrophobicContact CB-CE2 3.55Å; K94-F199 HydrophobicContact CB-CZ 4.36Å; K94-F199 HydrophobicContact CD-CE2 3.81Å; K94-F199 HydrophobicContact CD-CZ 3.81Å; K94-F199 HydrophobicContact CG-CE2 4.33Å
95Y94.8Very high93.5Very high81 Ų8164.3 Ų64.332%0.31834%0.337SS..Hα-helixtrans-49.9-55.4-175.7-164.8-73.1000113.8V91 E92 Y97 M98 V99 H197 F199 N200V91-Y95 PolarHBondContact O-N 3.19Å; E92-Y95 WeakPolarHBondContact O-CB 3.27Å; E92-Y95 PolarHBondContact O-N 3.36Å; Y95-Y97 PolarHBondContact O-N 2.75Å; Y95-M98 PolarHBondContact O-N 3.41Å; Y95-M98 VanDerWaalsContact O-N 3.11Å; Y95-V99 HydrophobicContact CD1-CG2 4.01Å; Y95-V99 HydrophobicContact CE1-CG2 3.81Å; Y95-V99 PolarHBondContact O-N 3.21Å; Y95-V99 VanDerWaalsContact O-N 3.16Å; Y95-H197 AromaticContact CD1-NE2 3.98Å; Y95-H197 AromaticContact CD2-CE1 3.63Å; Y95-H197 AromaticContact CE1-NE2 3.53Å; Y95-H197 AromaticContact CE2-CE1 3.58Å; Y95-H197 AromaticContact CE2-NE2 3.63Å; Y95-H197 AromaticContact CG-CE1 3.93Å; Y95-H197 AromaticContact CZ-CE1 3.8Å; Y95-H197 AromaticContact CZ-NE2 3.35Å; Y95-H197 VanDerWaalsContact CZ-NE2 3.35Å; Y95-F199 HydrophobicContact CD2-CB 4.37Å; Y95-N200 HydrophobicContact CE2-CB 3.61Å; Y95-N200 WeakPolarHBondContact OH-CB 3.18Å
96P97.6Very high94.2Very high77 Ų7764 Ų6450%0.533%0.334SS..Hα-helixtrans-62.4-30.9-179.125.2-35.8000113E92 E93 V99 E100E92-P96 WeakPolarHBondContact O-CD 3.13Å; E93-P96 WeakPolarHBondContact O-CD 3.15Å; P96-V99 PolarHBondContact O-N 2.7Å; P96-E100 WeakPolarHBondContact O-CB 3.43Å; P96-E100 PolarHBondContact O-N 2.97Å
97Y97.8Very high94.9Very high97 Ų9763 Ų6338%0.3834%0.336SS..Hα-helixtrans-69.4-36176.6-66.5-76000112.2Y80 I83 E93 K94 Y95 E100 W101Y80-Y97 VanDerWaalsContact CD1-O 3.29Å; Y80-Y97 WeakPolarHBondContact CD1-O 3.48Å; Y80-Y97 HydrophobicContact CE1-CD1 4.23Å; Y80-Y97 WeakPolarHBondContact CE1-O 3.38Å; I83-Y97 HydrophobicContact CD1-CD1 3.7Å; I83-Y97 HydrophobicContact CD1-CE1 4.07Å; I83-Y97 HydrophobicContact CD1-CG 4.02Å; I83-Y97 HydrophobicContact CG2-CD2 3.84Å; I83-Y97 HydrophobicContact CG2-CG 3.88Å; E93-Y97 VanDerWaalsContact O-CD2 3.25Å; E93-Y97 WeakPolarHBondContact O-CD2 3.09Å; E93-Y97 WeakPolarHBondContact O-CE2 3.21Å; K94-Y97 WeakPolarHBondContact O-CB 3.48Å; K94-Y97 PolarHBondContact O-N 3.46Å; K94-Y97 VanDerWaalsContact O-N 3.1Å; Y95-Y97 PolarHBondContact O-N 2.75Å; Y97-E100 PolarHBondContact O-N 3.41Å; Y97-W101 WeakPolarHBondContact O-CB 2.91Å; Y97-W101 PolarHBondContact O-N 3.38Å
98M97.5Very high95.7Very high0 Ų059.2 Ų59.20%031%0.31CS..Hα-helixtrans-67.5-42.2175.2-64.9-57.196.700111.1E84 K94 Y95 E100 W101 Y102 H197 V198 F199E84-M98 HydrophobicContact CB-CE 3.84Å; E84-M98 HydrophobicContact CB-SD 3.9Å; E84-M98 HydrophobicContact CG-SD 3.97Å; K94-M98 PolarHBondContact O-N 3.47Å; K94-M98 VanDerWaalsContact O-N 3.09Å; Y95-M98 PolarHBondContact O-N 3.41Å; Y95-M98 VanDerWaalsContact O-N 3.11Å; M98-E100 VanDerWaalsContact C-N 3.31Å; M98-E100 PolarHBondContact O-N 2.99Å; M98-W101 HydrophobicContact CE-CE3 3.99Å; M98-W101 PolarHBondContact O-N 3.04Å; M98-W101 HydrophobicContact SD-CE3 3.91Å; M98-W101 HydrophobicContact SD-CZ3 4.29Å; M98-Y102 VanDerWaalsContact O-CD2 3.25Å; M98-Y102 WeakPolarHBondContact O-CD2 3.28Å; M98-Y102 PolarHBondContact O-N 2.83Å; M98-H197 HydrophobicContact CB-CB 4.19Å; M98-V198 HydrophobicContact CG-CG1 3.97Å; M98-V198 HydrophobicContact SD-CG1 3.92Å; M98-F199 HydrophobicContact CG-CD2 3.52Å; M98-F199 HydrophobicContact CG-CE2 3.62Å; M98-F199 HydrophobicContact SD-CE2 4.2Å
99V97.4Very high96.2Very high52 Ų5253.3 Ų53.332%0.31527%0.274SS..Hα-helixtrans-58.3-46.2173.6176.90000110.9Y95 P96 T103 L195Y95-V99 HydrophobicContact CD1-CG2 4.01Å; Y95-V99 HydrophobicContact CE1-CG2 3.81Å; Y95-V99 PolarHBondContact O-N 3.21Å; Y95-V99 VanDerWaalsContact O-N 3.16Å; P96-V99 PolarHBondContact O-N 2.7Å; V99-T103 VanDerWaalsContact O-CB 3.24Å; V99-T103 WeakPolarHBondContact O-CB 3.32Å; V99-T103 PolarHBondContact O-N 2.78Å; V99-T103 PolarHBondContact O-OG1 3.3Å; V99-L195 HydrophobicContact CG1-CD2 4.41Å
100E98.3Very high96.5Very high72 Ų7253 Ų5334%0.33627%0.274SS..Hα-helixtrans-62.8-44.4178.8-166.3-171-176.600111.9Y80 P96 Y97 M98 K104Y80-E100 HydrophobicContact CE1-CB 4.14Å; Y80-E100 HydrophobicContact CE1-CG 4.35Å; Y80-E100 WeakPolarHBondContact CE1-OE2 3.38Å; Y80-E100 WeakPolarHBondContact OH-CG 3.44Å; Y80-E100 PolarHBondContact OH-OE1 3.16Å; Y80-E100 VanDerWaalsContact OH-OE1 3.06Å; Y80-E100 PolarHBondContact OH-OE2 2.98Å; P96-E100 WeakPolarHBondContact O-CB 3.43Å; P96-E100 PolarHBondContact O-N 2.97Å; Y97-E100 PolarHBondContact O-N 3.41Å; M98-E100 VanDerWaalsContact C-N 3.31Å; M98-E100 PolarHBondContact O-N 2.99Å; E100-K104 HydrophobicContact CG-CD 4.19Å; E100-K104 WeakPolarHBondContact O-CB 3.24Å; E100-K104 VanDerWaalsContact O-CG 3.32Å; E100-K104 WeakPolarHBondContact O-CG 3.48Å; E100-K104 PolarHBondContact O-N 2.97Å; E100-K104 WeakPolarHBondContact OE1-CE 3.08Å; E100-K104 IonicContact OE1-NZ 2.79Å; E100-K104 PolarHBondContact OE1-NZ 3.08Å
101W98.3Very high96.9Very high34 Ų3456.3 Ų56.313%0.12929%0.285CS..Hα-helixtrans-59.8-52.7179.3-174.913.4000111.8K77 Y80 Y81 E84 Y97 M98 T103 K104 S105K77-W101 HydrophobicContact CB-CZ2 4.07Å; K77-W101 HydrophobicContact CG-CZ2 4.05Å; Y80-W101 HydrophobicContact CD1-CB 3.71Å; Y80-W101 HydrophobicContact CD1-CG 4.31Å; Y80-W101 HydrophobicContact CD2-CB 3.67Å; Y80-W101 AromaticContact CD2-CD1 3.57Å; Y80-W101 HydrophobicContact CD2-CD2 4.4Å; Y80-W101 AromaticContact CD2-CG 3.6Å; Y80-W101 HydrophobicContact CD2-CG 3.6Å; Y80-W101 HydrophobicContact CE1-CB 4.27Å; Y80-W101 HydrophobicContact CE2-CB 4.29Å; Y80-W101 HydrophobicContact CG-CB 3.4Å; Y80-W101 AromaticContact CG-CD1 3.96Å; Y80-W101 HydrophobicContact CG-CD2 4.05Å; Y80-W101 AromaticContact CG-CG 3.51Å; Y80-W101 HydrophobicContact CG-CG 3.51Å; Y81-W101 HydrophobicContact CD2-CH2 4.49Å; E84-W101 VanDerWaalsContact OE2-CZ3 3.29Å; E84-W101 WeakPolarHBondContact OE2-CZ3 3.35Å; Y97-W101 WeakPolarHBondContact O-CB 2.91Å; Y97-W101 PolarHBondContact O-N 3.38Å; M98-W101 HydrophobicContact CE-CE3 3.99Å; M98-W101 PolarHBondContact O-N 3.04Å; M98-W101 HydrophobicContact SD-CE3 3.91Å; M98-W101 HydrophobicContact SD-CZ3 4.29Å; W101-T103 PolarHBondContact O-N 2.91Å; W101-K104 PolarHBondContact O-N 2.84Å; W101-S105 WeakPolarHBondContact O-CB 3.42Å; W101-S105 PolarHBondContact O-N 3.37Å
102Y98.1Very high97.3Very high30 Ų3055.4 Ų55.412%0.11828%0.277CS..Hα-helixtrans-64.2-42.9-177.8-86.8-100.7000111.3H56 M98 K104 S105 H106 A153 L195 H197H56-Y102 AromaticContact CE1-CE1 3.68Å; H56-Y102 AromaticContact NE2-CE1 3.83Å; M98-Y102 VanDerWaalsContact O-CD2 3.25Å; M98-Y102 WeakPolarHBondContact O-CD2 3.28Å; M98-Y102 PolarHBondContact O-N 2.83Å; Y102-K104 VanDerWaalsContact C-N 3.34Å; Y102-K104 PolarHBondContact O-N 2.69Å; Y102-S105 PolarHBondContact O-N 2.88Å; Y102-H106 AromaticContact CD1-CE1 3.98Å; Y102-H106 VanDerWaalsContact O-CB 3.25Å; Y102-H106 WeakPolarHBondContact O-CB 3.36Å; Y102-H106 PolarHBondContact O-N 3.08Å; Y102-A153 WeakPolarHBondContact CE1-O 3.45Å; Y102-A153 PolarHBondContact OH-O 2.98Å; Y102-L195 HydrophobicContact CD1-CD1 3.75Å; Y102-L195 HydrophobicContact CG-CD1 3.98Å; Y102-L195 HydrophobicContact CG-CD2 4.45Å; Y102-H197 HydrophobicContact CD2-CB 3.94Å; Y102-H197 HydrophobicContact CE2-CB 3.81Å; Y102-H197 HydrophobicContact CG-CB 4.41Å
103T97.9Very high97.5Very high86 Ų8651.3 Ų51.353%0.52827%0.267SS..Hα-helixtrans-60.6-44.1177.9-61.90000111.3V99 W101 G107V99-T103 VanDerWaalsContact O-CB 3.24Å; V99-T103 WeakPolarHBondContact O-CB 3.32Å; V99-T103 PolarHBondContact O-N 2.78Å; V99-T103 PolarHBondContact O-OG1 3.3Å; W101-T103 PolarHBondContact O-N 2.91Å; T103-G107 PolarHBondContact O-N 2.98Å
104K98.4Very high97.6Very high83 Ų8346.8 Ų46.836%0.36125%0.246SC..Hα-helixtrans-67.3-44.9176.7-73.3178.5-178.8174.90112.3L76 Y80 E100 W101 Y102 G107 L108L76-K104 HydrophobicContact CD1-CB 3.77Å; L76-K104 HydrophobicContact CD2-CB 4.04Å; L76-K104 HydrophobicContact CD2-CD 3.74Å; Y80-K104 HydrophobicContact CE2-CD 4.43Å; Y80-K104 PolarHBondContact OH-NZ 2.95Å; E100-K104 HydrophobicContact CG-CD 4.19Å; E100-K104 WeakPolarHBondContact O-CB 3.24Å; E100-K104 VanDerWaalsContact O-CG 3.32Å; E100-K104 WeakPolarHBondContact O-CG 3.48Å; E100-K104 PolarHBondContact O-N 2.97Å; E100-K104 WeakPolarHBondContact OE1-CE 3.08Å; E100-K104 IonicContact OE1-NZ 2.79Å; E100-K104 PolarHBondContact OE1-NZ 3.08Å; W101-K104 PolarHBondContact O-N 2.84Å; Y102-K104 VanDerWaalsContact C-N 3.34Å; Y102-K104 PolarHBondContact O-N 2.69Å; K104-G107 PolarHBondContact O-N 2.91Å; K104-L108 WeakPolarHBondContact O-CG 3.29Å; K104-L108 PolarHBondContact O-N 3.42Å
105S97.9Very high97.8Very high8 Ų847.9 Ų47.96%0.05626%0.255CS..Hα-helixtrans-61-52.9179.4-178.50000110.9W101 Y102 G107 L108 L109W101-S105 WeakPolarHBondContact O-CB 3.42Å; W101-S105 PolarHBondContact O-N 3.37Å; Y102-S105 PolarHBondContact O-N 2.88Å; S105-G107 VanDerWaalsContact C-N 3.32Å; S105-G107 PolarHBondContact O-N 3.43Å; S105-L108 WeakPolarHBondContact O-CB 3.49Å; S105-L108 PolarHBondContact O-N 2.94Å; S105-L108 VanDerWaalsContact O-N 3.11Å; S105-L109 WeakPolarHBondContact O-CG 3.49Å; S105-L109 PolarHBondContact O-N 3.24Å
106H98.4Very high98Very high16 Ų1649.1 Ų49.17%0.07426%0.262CS..Hα-helixtrans-59.1-41176.7-68.9172.4000112.4H56 Y102 L108 L109 V110 F191H56-H106 AromaticContact CE1-NE2 3.96Å; H56-H106 AromaticContact NE2-CD2 3.63Å; H56-H106 AromaticContact NE2-NE2 3.09Å; H56-H106 PolarHBondContact NE2-NE2 2.93Å; Y102-H106 AromaticContact CD1-CE1 3.98Å; Y102-H106 VanDerWaalsContact O-CB 3.25Å; Y102-H106 WeakPolarHBondContact O-CB 3.36Å; Y102-H106 PolarHBondContact O-N 3.08Å; H106-L108 VanDerWaalsContact C-N 3.33Å; H106-L108 PolarHBondContact O-N 3.16Å; H106-L109 PolarHBondContact O-N 2.86Å; H106-L109 VanDerWaalsContact O-N 3.17Å; H106-V110 WeakPolarHBondContact O-CG2 3.39Å; H106-V110 PolarHBondContact O-N 3Å; H106-F191 HydrophobicContact CB-CD2 3.75Å; H106-F191 HydrophobicContact CB-CE2 3.51Å; H106-F191 HydrophobicContact CB-CZ 4.35Å; H106-F191 AromaticContact CD2-CE2 3.57Å; H106-F191 AromaticContact CD2-CZ 3.5Å; H106-F191 AromaticContact CG-CD2 3.66Å; H106-F191 AromaticContact CG-CE2 3.42Å; H106-F191 VanDerWaalsContact CG-CE2 3.42Å; H106-F191 AromaticContact CG-CZ 3.84Å; H106-F191 AromaticContact ND1-CD2 3.69Å; H106-F191 AromaticContact ND1-CE2 3.89Å; H106-F191 AromaticContact ND1-CG 3.91Å; H106-F191 AromaticContact NE2-CE1 3.79Å; H106-F191 AromaticContact NE2-CZ 3.71Å
107G98.4Very high98Very high29 Ų2949.7 Ų49.730%0.29927%0.273SS..Hα-helixtrans-60.3-39.6175.200000113.3T103 K104 S105 Q111T103-G107 PolarHBondContact O-N 2.98Å; K104-G107 PolarHBondContact O-N 2.91Å; S105-G107 VanDerWaalsContact C-N 3.32Å; S105-G107 PolarHBondContact O-N 3.43Å; G107-Q111 WeakPolarHBondContact O-CG 3.17Å; G107-Q111 PolarHBondContact O-N 3.2Å
108L98.4Very high98Very high22 Ų2248.8 Ų48.812%0.11527%0.271CS..Hα-helixtrans-66.2-39.2173.9-71.4175.5000111.9K72 L73 L76 K104 S105 H106 Q111 Q112K72-L108 HydrophobicContact CB-CD1 3.76Å; K72-L108 HydrophobicContact CD-CD2 4.12Å; L73-L108 HydrophobicContact CD2-CB 4.14Å; L73-L108 HydrophobicContact CD2-CD1 3.92Å; L73-L108 HydrophobicContact CG-CD1 4.05Å; L76-L108 HydrophobicContact CD1-CD1 3.63Å; K104-L108 WeakPolarHBondContact O-CG 3.29Å; K104-L108 PolarHBondContact O-N 3.42Å; S105-L108 WeakPolarHBondContact O-CB 3.49Å; S105-L108 PolarHBondContact O-N 2.94Å; S105-L108 VanDerWaalsContact O-N 3.11Å; H106-L108 VanDerWaalsContact C-N 3.33Å; H106-L108 PolarHBondContact O-N 3.16Å; L108-Q111 WeakPolarHBondContact O-CB 3.37Å; L108-Q111 PolarHBondContact O-N 2.95Å; L108-Q112 PolarHBondContact O-N 2.86Å
109L97.9Very high98Very high0 Ų049.2 Ų49.20%027%0.273CS..Hα-helixtrans-65.4-41.2176.9-61.9-173.6000112.1I59 L73 S105 H106 Q111 Q112 L114 I155 L188I59-L109 HydrophobicContact CB-CD1 4.48Å; I59-L109 HydrophobicContact CG2-CD1 4.04Å; I59-L109 HydrophobicContact CG2-CD2 3.73Å; I59-L109 HydrophobicContact CG2-CG 4.42Å; L73-L109 HydrophobicContact CD1-CD2 4Å; L73-L109 HydrophobicContact CD2-CD2 4.47Å; S105-L109 WeakPolarHBondContact O-CG 3.49Å; S105-L109 PolarHBondContact O-N 3.24Å; H106-L109 PolarHBondContact O-N 2.86Å; H106-L109 VanDerWaalsContact O-N 3.17Å; L109-Q111 VanDerWaalsContact C-N 3.28Å; L109-Q111 PolarHBondContact O-N 2.74Å; L109-Q112 WeakPolarHBondContact O-CB 3.47Å; L109-Q112 PolarHBondContact O-N 2.81Å; L109-L114 HydrophobicContact CB-CD1 4.2Å; L109-I155 HydrophobicContact CD1-CD1 4.06Å; L109-L188 HydrophobicContact CB-CD2 4.1Å
110V98.1Very high98.1Very high43 Ų4353.5 Ų53.526%0.26129%0.287SS..Hα-helixtrans-58.3-41.6174.1171.40000110.7H106 Q112 A113 L188H106-V110 WeakPolarHBondContact O-CG2 3.39Å; H106-V110 PolarHBondContact O-N 3Å; V110-Q112 PolarHBondContact O-N 2.75Å; V110-A113 PolarHBondContact O-N 2.89Å; V110-L188 HydrophobicContact CG2-CD2 4.2Å; V110-L188 HydrophobicContact CG2-CG 4.02Å
111Q98Very high98.1Very high136 Ų13654.6 Ų54.664%0.63629%0.293SS*.Hα-helixtrans-64.3-19.2177.3-69.5169.223.100113.9G107 L108 L109 A113G107-Q111 WeakPolarHBondContact O-CG 3.17Å; G107-Q111 PolarHBondContact O-N 3.2Å; L108-Q111 WeakPolarHBondContact O-CB 3.37Å; L108-Q111 PolarHBondContact O-N 2.95Å; L109-Q111 VanDerWaalsContact C-N 3.28Å; L109-Q111 PolarHBondContact O-N 2.74Å; Q111-A113 VanDerWaalsContact C-N 3.26Å
112Q98.2Very high98.1Very high41 Ų4153.7 Ų53.719%0.19229%0.29CS..THydrogen-bonded Turntrans-82.7-0.4174.6-58.2-57.5-90.700113.1V65 T66 C69 L108 L109 V110 L114V65-Q112 HydrophobicContact CG1-CG 4.41Å; V65-Q112 HydrophobicContact CG2-CG 4.27Å; T66-Q112 PolarHBondContact OG1-OE1 2.87Å; C69-Q112 HydrophobicContact CB-CG 4.25Å; L108-Q112 PolarHBondContact O-N 2.86Å; L109-Q112 WeakPolarHBondContact O-CB 3.47Å; L109-Q112 PolarHBondContact O-N 2.81Å; V110-Q112 PolarHBondContact O-N 2.75Å; Q112-L114 VanDerWaalsContact C-N 3.34Å; Q112-L114 HydrophobicContact CB-CD2 4.13Å; Q112-L114 HydrophobicContact CB-CG 4.22Å; Q112-L114 PolarHBondContact O-N 3.34Å
113A96.6Very high98.2Very high55 Ų5552.4 Ų52.446%0.45529%0.286SS..THydrogen-bonded Turntrans51.848.6176.100000113.2V110 Q111 P115 V187V110-A113 PolarHBondContact O-N 2.89Å; Q111-A113 VanDerWaalsContact C-N 3.26Å; A113-P115 WeakPolarHBondContact O-CD 3.31Å; A113-V187 HydrophobicContact CB-CG1 3.75Å
114L97.4Very high98.2Very high2 Ų251.4 Ų51.41%0.0129%0.286CS..  trans-66.4121.1-174.1-61.9173.1000111.7I59 L64 V65 L109 Q112 L188I59-L114 HydrophobicContact CG2-CD1 3.36Å; L64-L114 HydrophobicContact CB-CD2 3.77Å; L64-L114 HydrophobicContact CD1-CD2 4.33Å; V65-L114 HydrophobicContact CG2-CD2 4.39Å; L109-L114 HydrophobicContact CB-CD1 4.2Å; Q112-L114 VanDerWaalsContact C-N 3.34Å; Q112-L114 HydrophobicContact CB-CD2 4.13Å; Q112-L114 HydrophobicContact CB-CG 4.22Å; Q112-L114 PolarHBondContact O-N 3.34Å; L114-L188 HydrophobicContact CB-CB 4.06Å; L114-L188 HydrophobicContact CB-CD2 4.28Å; L114-L188 HydrophobicContact CD1-CD2 3.94Å; L114-L188 HydrophobicContact CG-CD2 4.45Å; L114-L188 WeakPolarHBondContact O-CB 3.45Å; L114-L188 PolarHBondContact O-N 3.25Å
115P98.1Very high98.2Very high41 Ų4152.9 Ų52.927%0.26629%0.294SS..BIsolated β-bridgetrans-82.8131.8178.730.2-30.7000111.6L64 A113 A117 K118 G186L64-P115 HydrophobicContact CD1-CG 4.04Å; A113-P115 WeakPolarHBondContact O-CD 3.31Å; P115-A117 PolarHBondContact O-N 3.14Å; P115-A117 VanDerWaalsContact O-N 3.17Å; P115-K118 HydrophobicContact CB-CG 4.48Å; P115-K118 HydrophobicContact CG-CB 3.93Å; P115-K118 HydrophobicContact CG-CG 3.59Å; P115-K118 PolarHBondContact O-N 3.17Å; P115-G186 CarbonylContact C-O 3.57Å; P115-G186 WeakPolarHBondContact CA-O 3.43Å
116K98.3Very high98.2Very high108 Ų10853.9 Ų53.947%0.4730%0.301SS..G310 helixtrans-52.6-40.9178.4-170.7176.4-175.8174.30112.7K118 L119 F182 G186K116-K118 PolarHBondContact O-N 2.9Å; K116-K118 VanDerWaalsContact O-N 3.1Å; K116-L119 HydrophobicContact CG-CD1 4.39Å; K116-L119 WeakPolarHBondContact O-CB 3.33Å; K116-L119 WeakPolarHBondContact O-CG 3.2Å; K116-L119 PolarHBondContact O-N 2.77Å; K116-L119 VanDerWaalsContact O-N 3.14Å; K116-F182 HydrophobicContact CB-CD1 3.7Å; K116-F182 HydrophobicContact CB-CD2 4.23Å; K116-F182 HydrophobicContact CB-CE1 3.54Å; K116-F182 HydrophobicContact CB-CE2 4.06Å; K116-F182 HydrophobicContact CB-CG 4.06Å; K116-F182 HydrophobicContact CB-CZ 3.73Å; K116-F182 HydrophobicContact CD-CD2 3.77Å; K116-F182 HydrophobicContact CD-CE2 3.75Å; K116-F182 HydrophobicContact CD-CG 4.27Å; K116-F182 HydrophobicContact CD-CZ 4.26Å; K116-F182 HydrophobicContact CG-CD1 4.46Å; K116-F182 HydrophobicContact CG-CD2 4.16Å; K116-F182 HydrophobicContact CG-CE1 4.13Å; K116-F182 HydrophobicContact CG-CE2 3.77Å; K116-F182 HydrophobicContact CG-CG 4.49Å; K116-F182 HydrophobicContact CG-CZ 3.76Å; K116-G186 PolarHBondContact N-O 3.41Å
117A97.9Very high98.2Very high88 Ų8857.9 Ų57.973%0.72732%0.323SS*.G310 helixtrans-61.5-20.3-177.600000113.7P115P115-A117 PolarHBondContact O-N 3.14Å; P115-A117 VanDerWaalsContact O-N 3.17Å
118K98.4Very high98.2Very high79 Ų7958 Ų5834%0.34332%0.318SS..G310 helixtrans-91.1-8.9179.7-67-62.4-173.3-179.90114.3L64 P115 K116 K120 E121 I122L64-K118 HydrophobicContact CD1-CB 3.94Å; L64-K118 HydrophobicContact CD1-CG 4.23Å; P115-K118 HydrophobicContact CB-CG 4.48Å; P115-K118 HydrophobicContact CG-CB 3.93Å; P115-K118 HydrophobicContact CG-CG 3.59Å; P115-K118 PolarHBondContact O-N 3.17Å; K116-K118 PolarHBondContact O-N 2.9Å; K116-K118 VanDerWaalsContact O-N 3.1Å; K118-K120 PolarHBondContact O-N 3.43Å; K118-E121 VanDerWaalsContact CD-OE2 3.31Å; K118-E121 WeakPolarHBondContact CD-OE2 3.26Å; K118-E121 IonicContact NZ-OE1 2.62Å; K118-E121 PolarHBondContact NZ-OE1 3.22Å; K118-E121 IonicContact NZ-OE2 2.7Å; K118-E121 PolarHBondContact NZ-OE2 3.34Å; K118-E121 PolarHBondContact O-N 3.06Å; K118-E121 VanDerWaalsContact O-N 3.11Å; K118-I122 HydrophobicContact CB-CD1 4.11Å; K118-I122 VanDerWaalsContact O-CG1 3.26Å; K118-I122 WeakPolarHBondContact O-CG1 3.37Å; K118-I122 PolarHBondContact O-N 3.09Å
119L98.5Very high98.2Very high9 Ų959.7 Ų59.75%0.04733%0.326CS..Hα-helixtrans-57.3-38.8-179.5-68.1-179.9000112.6I59 K116 E121 I122 V123 D157 V158 M180 F182I59-L119 HydrophobicContact CD1-CD2 3.87Å; K116-L119 HydrophobicContact CG-CD1 4.39Å; K116-L119 WeakPolarHBondContact O-CB 3.33Å; K116-L119 WeakPolarHBondContact O-CG 3.2Å; K116-L119 PolarHBondContact O-N 2.77Å; K116-L119 VanDerWaalsContact O-N 3.14Å; L119-E121 PolarHBondContact O-N 3.34Å; L119-I122 HydrophobicContact CD2-CD1 4.42Å; L119-I122 PolarHBondContact O-N 3.36Å; L119-V123 WeakPolarHBondContact O-CG2 3.43Å; L119-V123 PolarHBondContact O-N 2.83Å; L119-D157 HydrophobicContact CD1-CB 3.7Å; L119-V158 HydrophobicContact CD2-CG2 4.42Å; L119-M180 HydrophobicContact CD1-SD 4.47Å; L119-M180 HydrophobicContact CD2-SD 4.48Å; L119-F182 HydrophobicContact CD1-CZ 4.09Å
120K98.5Very high98.3Very high141 Ų14160.5 Ų60.561%0.61333%0.33SS*.Hα-helixtrans-58.3-49.2175.4177167.3-175179.80112.6K118 A124 E161 Q165K118-K120 PolarHBondContact O-N 3.43Å; K120-A124 WeakPolarHBondContact O-CB 3.31Å; K120-A124 PolarHBondContact O-N 2.93Å; K120-A124 VanDerWaalsContact O-N 3.08Å; K120-E161 WeakPolarHBondContact CB-OE1 3.4Å; K120-E161 VanDerWaalsContact CG-OE1 3.3Å; K120-E161 WeakPolarHBondContact CG-OE1 3.26Å; K120-Q165 PolarHBondContact O-NE2 3.36Å
121E98.6Very high98.3Very high96 Ų9658.4 Ų58.445%0.44932%0.318SS..Hα-helixtrans-65.7-43.5178.2-66.9171.5-149.300110.8K118 L119 V123 A124 E125K118-E121 VanDerWaalsContact CD-OE2 3.31Å; K118-E121 WeakPolarHBondContact CD-OE2 3.26Å; K118-E121 IonicContact NZ-OE1 2.62Å; K118-E121 PolarHBondContact NZ-OE1 3.22Å; K118-E121 IonicContact NZ-OE2 2.7Å; K118-E121 PolarHBondContact NZ-OE2 3.34Å; K118-E121 PolarHBondContact O-N 3.06Å; K118-E121 VanDerWaalsContact O-N 3.11Å; L119-E121 PolarHBondContact O-N 3.34Å; E121-V123 VanDerWaalsContact C-N 3.35Å; E121-V123 PolarHBondContact O-N 2.87Å; E121-A124 PolarHBondContact O-N 3.17Å; E121-E125 WeakPolarHBondContact O-CB 3.4Å; E121-E125 WeakPolarHBondContact O-CG 3.47Å; E121-E125 PolarHBondContact O-N 2.85Å
122I98.7Very high98.3Very high14 Ų1457.1 Ų57.17%0.07231%0.312CS..Hα-helixtrans-58.3-46.5179.3-70.4164.2000111.3I58 I59 C62 L64 K118 L119 S126I58-I122 HydrophobicContact CG2-CG2 3.77Å; I59-I122 HydrophobicContact CD1-CG2 4.06Å; C62-I122 HydrophobicContact CB-CB 4.33Å; C62-I122 HydrophobicContact CB-CD1 4.42Å; C62-I122 HydrophobicContact CB-CG1 3.99Å; C62-I122 HydrophobicContact CB-CG2 3.54Å; L64-I122 HydrophobicContact CD1-CD1 3.91Å; L64-I122 HydrophobicContact CG-CD1 4.48Å; K118-I122 HydrophobicContact CB-CD1 4.11Å; K118-I122 VanDerWaalsContact O-CG1 3.26Å; K118-I122 WeakPolarHBondContact O-CG1 3.37Å; K118-I122 PolarHBondContact O-N 3.09Å; L119-I122 HydrophobicContact CD2-CD1 4.42Å; L119-I122 PolarHBondContact O-N 3.36Å; I122-S126 PolarHBondContact O-N 3.18Å
123V98.8Very high98.4Very high4 Ų456.2 Ų56.22%0.02431%0.313CS..Hα-helixtrans-67-44.2178.9170.20000111I58 L119 E121 E125 S126 V158 E161 V162I58-V123 HydrophobicContact CG2-CG2 4.19Å; L119-V123 WeakPolarHBondContact O-CG2 3.43Å; L119-V123 PolarHBondContact O-N 2.83Å; E121-V123 VanDerWaalsContact C-N 3.35Å; E121-V123 PolarHBondContact O-N 2.87Å; V123-E125 VanDerWaalsContact C-N 3.26Å; V123-E125 PolarHBondContact O-N 3.29Å; V123-S126 WeakPolarHBondContact O-CB 3.48Å; V123-S126 PolarHBondContact O-N 3.09Å; V123-S126 VanDerWaalsContact O-N 3.08Å; V123-S126 PolarHBondContact O-OG 2.78Å; V123-V158 HydrophobicContact CG2-CG1 4.02Å; V123-E161 HydrophobicContact CB-CB 4.49Å; V123-E161 HydrophobicContact CB-CG 3.91Å; V123-E161 HydrophobicContact CG1-CG 4.19Å; V123-E161 HydrophobicContact CG2-CB 4.02Å; V123-E161 HydrophobicContact CG2-CG 3.9Å; V123-V162 HydrophobicContact CG1-CB 4.41Å; V123-V162 HydrophobicContact CG1-CG2 3.72Å; V123-V162 HydrophobicContact CG2-CG2 4.42Å
124A98.6Very high98.5Very high65 Ų6556 Ų5654%0.53730%0.301SS..Hα-helixtrans-62.9-31.5-179.400000113.2K120 E121K120-A124 WeakPolarHBondContact O-CB 3.31Å; K120-A124 PolarHBondContact O-N 2.93Å; K120-A124 VanDerWaalsContact O-N 3.08Å; E121-A124 PolarHBondContact O-N 3.17Å
125E98.2Very high98.5Very high114 Ų11460.1 Ų60.153%0.53332%0.32SS..THydrogen-bonded Turntrans-87.8-4177.5-67-173.8159.300113.8K63 E121 V123K63-E125 WeakPolarHBondContact CE-OE2 3.3Å; K63-E125 IonicContact NZ-OE1 3.34Å; K63-E125 PolarHBondContact NZ-OE1 3.34Å; K63-E125 IonicContact NZ-OE2 3.01Å; K63-E125 PolarHBondContact NZ-OE2 2.72Å; E121-E125 WeakPolarHBondContact O-CB 3.4Å; E121-E125 WeakPolarHBondContact O-CG 3.47Å; E121-E125 PolarHBondContact O-N 2.85Å; V123-E125 VanDerWaalsContact C-N 3.26Å; V123-E125 PolarHBondContact O-N 3.29Å
126S98.4Very high98.5Very high29 Ų2961.9 Ų61.920%0.20333%0.327CS..SBendtrans-84.1162.7-176.177.80000113.2I122 V123 V128I122-S126 PolarHBondContact O-N 3.18Å; V123-S126 WeakPolarHBondContact O-CB 3.48Å; V123-S126 PolarHBondContact O-N 3.09Å; V123-S126 VanDerWaalsContact O-N 3.08Å; V123-S126 PolarHBondContact O-OG 2.78Å; S126-V128 PolarHBondContact O-N 3.22Å; S126-V128 VanDerWaalsContact OG-CG1 3.31Å; S126-V128 WeakPolarHBondContact OG-CG1 3.48Å
127D98.1Very high98.6Very high100 Ų10056.8 Ų56.854%0.53531%0.305SS..  trans-86.419.7176-68.5-29.9000112.9K50 P53K50-D127 IonicContact NZ-OD2 2.65Å; K50-D127 PolarHBondContact NZ-OD2 2.91Å; P53-D127 VanDerWaalsContact CD-O 3.31Å; P53-D127 WeakPolarHBondContact CD-O 3.28Å; P53-D127 HydrophobicContact CG-CB 4.37Å
128V98.6Very high98.6Very high31 Ų3152.6 Ų52.619%0.18827%0.271CS..  trans-64.6138.6-178.770.40000110.7P53 I58 S126 V162P53-V128 HydrophobicContact CG-CB 4.22Å; I58-V128 HydrophobicContact CD1-CB 3.75Å; I58-V128 HydrophobicContact CD1-CG1 4.24Å; I58-V128 HydrophobicContact CD1-CG2 3.85Å; I58-V128 HydrophobicContact CG1-CB 4.28Å; S126-V128 PolarHBondContact O-N 3.22Å; S126-V128 VanDerWaalsContact OG-CG1 3.31Å; S126-V128 WeakPolarHBondContact OG-CG1 3.48Å; V128-V162 HydrophobicContact CG1-CG1 4.23Å; V128-V162 HydrophobicContact CG1-CG2 4.11Å; V128-V162 HydrophobicContact CG2-CG1 4.07Å; V128-V162 HydrophobicContact CG2-CG2 4.18Å
129M98.8Very high98.6Very high58 Ų5852.5 Ų52.529%0.28627%0.274SS..  trans-136.2134.2176-61.6-167.381.600109.8S43 R44 Y47S43-M129 CarbonylContact C-O 3.54Å; S43-M129 VanDerWaalsContact CA-O 3.3Å; S43-M129 WeakPolarHBondContact CA-O 3.33Å; S43-M129 WeakPolarHBondContact CB-O 3.33Å; R44-M129 HydrophobicContact CB-CB 4.29Å; R44-M129 HydrophobicContact CG-CB 4.05Å; R44-M129 PolarHBondContact N-O 3.15Å; Y47-M129 HydrophobicContact CD1-CE 4.36Å; Y47-M129 HydrophobicContact CD1-SD 3.55Å; Y47-M129 VanDerWaalsContact CD1-SD 3.55Å; Y47-M129 HydrophobicContact CD2-CE 4.05Å; Y47-M129 HydrophobicContact CD2-SD 3.67Å; Y47-M129 HydrophobicContact CE1-CE 4.28Å; Y47-M129 HydrophobicContact CE1-SD 4.05Å; Y47-M129 HydrophobicContact CE2-CE 3.96Å; Y47-M129 HydrophobicContact CE2-SD 4.15Å; Y47-M129 HydrophobicContact CG-CE 4.24Å; Y47-M129 HydrophobicContact CG-SD 3.34Å
130L98.9Very high98.6Very high16 Ų1652.9 Ų52.98%0.08428%0.275CS..BIsolated β-bridgetrans-79.8151.5167.2-63.9177000110.2F38 L42 R44 Y134 V162 A166 V168F38-L130 HydrophobicContact CE2-CD2 4.07Å; F38-L130 HydrophobicContact CZ-CD2 4.12Å; L42-L130 WeakPolarHBondContact O-CA 3.47Å; R44-L130 WeakPolarHBondContact CG-O 3.42Å; R44-L130 PolarHBondContact NE-O 3.07Å; L130-Y134 HydrophobicContact CB-CD1 3.5Å; L130-Y134 VanDerWaalsContact CB-CD1 3.5Å; L130-Y134 HydrophobicContact CB-CD2 4.28Å; L130-Y134 HydrophobicContact CB-CE1 4.03Å; L130-Y134 HydrophobicContact CB-CG 3.64Å; L130-Y134 HydrophobicContact CD1-CD1 4.19Å; L130-Y134 HydrophobicContact CD1-CD2 3.46Å; L130-Y134 VanDerWaalsContact CD1-CD2 3.46Å; L130-Y134 HydrophobicContact CD1-CE1 4.4Å; L130-Y134 HydrophobicContact CD1-CE2 3.74Å; L130-Y134 HydrophobicContact CD1-CG 3.72Å; L130-Y134 HydrophobicContact CG-CD1 4.48Å; L130-Y134 HydrophobicContact CG-CG 4.34Å; L130-V162 HydrophobicContact CD2-CG1 4.23Å; L130-A166 HydrophobicContact CD1-CB 3.75Å; L130-V168 HydrophobicContact CD1-CG2 4.42Å
131K98.9Very high98.6Very high0 Ų046.1 Ų46.10%025%0.246CC..PPolyproline II helixtrans-59.7149.6174.9-74.5-167-170-78.20110.5M40 T41 L42 R44 G133 Y134 Y248 D271 E272 L274M40-K131 VanDerWaalsContact O-CE 3.25Å; M40-K131 WeakPolarHBondContact O-CE 3.35Å; M40-K131 PolarHBondContact O-NZ 2.99Å; T41-K131 WeakPolarHBondContact O-CD 3.06Å; T41-K131 WeakPolarHBondContact O-CE 3.5Å; L42-K131 PolarHBondContact O-N 3.42Å; R44-K131 HydrophobicContact CG-CG 4.21Å; K131-G133 PolarHBondContact O-N 3.35Å; K131-Y134 WeakPolarHBondContact O-CB 3.32Å; K131-Y134 WeakPolarHBondContact O-CD1 3.46Å; K131-Y134 PolarHBondContact O-N 3.27Å; K131-Y248 HydrophobicContact CD-CD1 4.21Å; K131-Y248 HydrophobicContact CD-CE1 3.72Å; K131-D271 PolarHBondContact NZ-O 3.14Å; K131-E272 CarbonylContact C-O 3.59Å; K131-E272 VanDerWaalsContact CA-O 3.29Å; K131-E272 WeakPolarHBondContact CA-O 3.31Å; K131-E272 WeakPolarHBondContact CB-O 3.47Å; K131-E272 IonicContact NZ-OE2 3.76Å; K131-E272 PolarHBondContact NZ-OE2 2.71Å; K131-L274 HydrophobicContact CB-CD2 4.45Å; K131-L274 HydrophobicContact CB-CG 3.96Å; K131-L274 HydrophobicContact CD-CD2 4.37Å
132E98.8Very high98.6Very high109 Ų10944.3 Ų44.351%0.50924%0.237SC..BIsolated β-bridgetrans-58135179.7-173.7171.4157.700111.8E272 S273 L274E132-E272 PolarHBondContact N-O 3.1Å; E132-S273 WeakPolarHBondContact O-CA 3.35Å; E132-L274 PolarHBondContact O-N 2.62Å
133G98.7Very high98.6Very high22 Ų2250.8 Ų50.823%0.22727%0.267CS..THydrogen-bonded Turntrans82.717.4-178.200000114.6K131 E135 F137 N278K131-G133 PolarHBondContact O-N 3.35Å; G133-E135 VanDerWaalsContact C-N 3.33Å; G133-F137 PolarHBondContact O-N 3.16Å; G133-F137 VanDerWaalsContact O-N 3.1Å; G133-N278 PolarHBondContact O-ND2 2.79Å
134Y98.9Very high98.6Very high51 Ų5153.4 Ų53.420%0.228%0.279CS..Hα-helixtrans-63.7-36.3177.475.8-92.1000112.7L130 K131 F137 F138 A166 V168L130-Y134 HydrophobicContact CB-CD1 3.5Å; L130-Y134 VanDerWaalsContact CB-CD1 3.5Å; L130-Y134 HydrophobicContact CB-CD2 4.28Å; L130-Y134 HydrophobicContact CB-CE1 4.03Å; L130-Y134 HydrophobicContact CB-CG 3.64Å; L130-Y134 HydrophobicContact CD1-CD1 4.19Å; L130-Y134 HydrophobicContact CD1-CD2 3.46Å; L130-Y134 VanDerWaalsContact CD1-CD2 3.46Å; L130-Y134 HydrophobicContact CD1-CE1 4.4Å; L130-Y134 HydrophobicContact CD1-CE2 3.74Å; L130-Y134 HydrophobicContact CD1-CG 3.72Å; L130-Y134 HydrophobicContact CG-CD1 4.48Å; L130-Y134 HydrophobicContact CG-CG 4.34Å; K131-Y134 WeakPolarHBondContact O-CB 3.32Å; K131-Y134 WeakPolarHBondContact O-CD1 3.46Å; K131-Y134 PolarHBondContact O-N 3.27Å; Y134-F137 WeakPolarHBondContact O-CB 3.38Å; Y134-F137 PolarHBondContact O-N 3.44Å; Y134-F138 HydrophobicContact CD2-CD2 4.48Å; Y134-F138 VanDerWaalsContact O-CD2 3.28Å; Y134-F138 WeakPolarHBondContact O-CD2 3.49Å; Y134-F138 PolarHBondContact O-N 3.17Å; Y134-A166 HydrophobicContact CE2-CB 3.9Å; Y134-V168 HydrophobicContact CD2-CG1 3.96Å; Y134-V168 HydrophobicContact CD2-CG2 4.2Å; Y134-V168 HydrophobicContact CE2-CG1 3.92Å; Y134-V168 HydrophobicContact CE2-CG2 4.38Å
135E98.7Very high98.6Very high88 Ų8854.4 Ų54.441%0.41128%0.282SS..Hα-helixtrans-58.9-54179-58.492.6144.800109.6G133 F137 F138 D139G133-E135 VanDerWaalsContact C-N 3.33Å; E135-F137 VanDerWaalsContact C-N 3.28Å; E135-F137 PolarHBondContact O-N 2.84Å; E135-F138 PolarHBondContact O-N 2.88Å; E135-D139 WeakPolarHBondContact O-CB 3.25Å; E135-D139 PolarHBondContact O-N 3.45Å
136N98.6Very high98.6Very high78 Ų7849 Ų4942%0.41726%0.257SS..Hα-helixtrans-60.9-37.4177.8-179.657.7000112.4K140N136-K140 WeakPolarHBondContact O-CB 3.44Å; N136-K140 PolarHBondContact O-N 2.86Å; N136-K140 VanDerWaalsContact O-N 3.08Å
137F98.9Very high98.6Very high1 Ų148.5 Ų48.50%0.00425%0.253CS..Hα-helixtrans-59.8-56.2176.6-179.6-98.6000111I34 L42 G133 Y134 E135 L141 L224 L274 A277 N278 L281I34-F137 HydrophobicContact CG2-CZ 4.04Å; L42-F137 HydrophobicContact CD2-CD1 4.47Å; L42-F137 HydrophobicContact CD2-CE1 4.07Å; G133-F137 PolarHBondContact O-N 3.16Å; G133-F137 VanDerWaalsContact O-N 3.1Å; Y134-F137 WeakPolarHBondContact O-CB 3.38Å; Y134-F137 PolarHBondContact O-N 3.44Å; E135-F137 VanDerWaalsContact C-N 3.28Å; E135-F137 PolarHBondContact O-N 2.84Å; F137-L141 HydrophobicContact CD1-CD1 3.84Å; F137-L141 HydrophobicContact CD2-CD1 4.26Å; F137-L141 HydrophobicContact CE1-CD1 3.55Å; F137-L141 HydrophobicContact CE2-CD1 4Å; F137-L141 HydrophobicContact CG-CD1 4.19Å; F137-L141 HydrophobicContact CZ-CD1 3.64Å; F137-L141 WeakPolarHBondContact O-CB 3.39Å; F137-L141 VanDerWaalsContact O-CD1 3.25Å; F137-L141 WeakPolarHBondContact O-CD1 3.38Å; F137-L141 WeakPolarHBondContact O-CG 3.44Å; F137-L141 PolarHBondContact O-N 3.45Å; F137-L224 HydrophobicContact CE2-CD1 3.97Å; F137-L224 HydrophobicContact CZ-CD1 3.7Å; F137-L274 HydrophobicContact CB-CD1 3.86Å; F137-L274 HydrophobicContact CD1-CD1 4.25Å; F137-L274 HydrophobicContact CD2-CD1 4.41Å; F137-L274 HydrophobicContact CG-CD1 3.93Å; F137-A277 HydrophobicContact CD2-CB 4.48Å; F137-A277 HydrophobicContact CE2-CB 4.25Å; F137-N278 WeakPolarHBondContact CA-OD1 3.4Å; F137-N278 VanDerWaalsContact CB-OD1 3.27Å; F137-N278 WeakPolarHBondContact CB-OD1 3.34Å; F137-N278 PolarHBondContact N-OD1 3.3Å; F137-L281 HydrophobicContact CD2-CD1 3.65Å; F137-L281 HydrophobicContact CE2-CD1 3.78Å
138F98.9Very high98.7Very high0 Ų043.7 Ų43.70%023%0.227CC..Hα-helixtrans-69-43.4-177.6-79.6-75.9000112.8L42 Y134 E135 L141 Q142 I150 V168 V173L42-F138 HydrophobicContact CD1-CZ 4Å; Y134-F138 HydrophobicContact CD2-CD2 4.48Å; Y134-F138 VanDerWaalsContact O-CD2 3.28Å; Y134-F138 WeakPolarHBondContact O-CD2 3.49Å; Y134-F138 PolarHBondContact O-N 3.17Å; E135-F138 PolarHBondContact O-N 2.88Å; F138-L141 PolarHBondContact O-N 3.18Å; F138-Q142 WeakPolarHBondContact O-CB 3.39Å; F138-Q142 PolarHBondContact O-N 3.11Å; F138-I150 HydrophobicContact CE1-CD1 4.21Å; F138-I150 HydrophobicContact CZ-CD1 4.24Å; F138-V168 HydrophobicContact CB-CB 3.65Å; F138-V168 HydrophobicContact CB-CG1 3.87Å; F138-V168 HydrophobicContact CD1-CB 4.31Å; F138-V168 HydrophobicContact CD2-CB 3.73Å; F138-V168 HydrophobicContact CD2-CG1 4.18Å; F138-V168 HydrophobicContact CD2-CG2 3.68Å; F138-V168 HydrophobicContact CE2-CB 4.46Å; F138-V168 HydrophobicContact CE2-CG2 3.95Å; F138-V168 HydrophobicContact CG-CB 3.65Å; F138-V168 HydrophobicContact CG-CG1 4.26Å; F138-V168 HydrophobicContact CG-CG2 4.05Å; F138-V173 HydrophobicContact CD1-CG2 4.03Å; F138-V173 HydrophobicContact CE1-CG2 4.05Å
139D98.5Very high98.7Very high77 Ų7742.2 Ų42.241%0.41222%0.218SC..Hα-helixtrans-67.6-40.9-175.6-68.5-13.6000111.6E135 Q142 Q143 H170E135-D139 WeakPolarHBondContact O-CB 3.25Å; E135-D139 PolarHBondContact O-N 3.45Å; D139-Q142 PolarHBondContact O-N 3.49Å; D139-Q143 VanDerWaalsContact O-CB 3.32Å; D139-Q143 WeakPolarHBondContact O-CB 3.45Å; D139-Q143 PolarHBondContact O-N 2.8Å; D139-H170 IonicContact OD1-CD2 2.57Å; D139-H170 IonicContact OD1-CE1 3.66Å; D139-H170 IonicContact OD1-NE2 2.88Å; D139-H170 PolarHBondContact OD1-NE2 2.91Å
140K98.5Very high98.7Very high16 Ų1639.5 Ų39.57%0.0721%0.205CC..Hα-helixtrans-67.6-38.3177.7-174.8163.2169.9124.40111.9N136 H144 L281 Q282 L285N136-K140 WeakPolarHBondContact O-CB 3.44Å; N136-K140 PolarHBondContact O-N 2.86Å; N136-K140 VanDerWaalsContact O-N 3.08Å; K140-H144 PolarHBondContact O-N 2.77Å; K140-H144 PolarHBondContact O-ND1 3.14Å; K140-L281 WeakPolarHBondContact CE-O 3.21Å; K140-Q282 VanDerWaalsContact NZ-CD 3.28Å; K140-L285 WeakPolarHBondContact CE-O 3.47Å; K140-L285 HydrophobicContact CG-CD1 4.14Å; K140-L285 PolarHBondContact NZ-O 3.42Å
141L98.8Very high98.7Very high0 Ų038.7 Ų38.70%020%0.201CC..Hα-helixtrans-64.5-45173.9-69.2168.4000111.1I34 F137 F138 H144 S145 I146 V148 L281 L285I34-L141 HydrophobicContact CD1-CD2 3.95Å; I34-L141 HydrophobicContact CG1-CD1 3.91Å; I34-L141 HydrophobicContact CG1-CD2 3.6Å; I34-L141 HydrophobicContact CG1-CG 4.42Å; F137-L141 HydrophobicContact CD1-CD1 3.84Å; F137-L141 HydrophobicContact CD2-CD1 4.26Å; F137-L141 HydrophobicContact CE1-CD1 3.55Å; F137-L141 HydrophobicContact CE2-CD1 4Å; F137-L141 HydrophobicContact CG-CD1 4.19Å; F137-L141 HydrophobicContact CZ-CD1 3.64Å; F137-L141 WeakPolarHBondContact O-CB 3.39Å; F137-L141 VanDerWaalsContact O-CD1 3.25Å; F137-L141 WeakPolarHBondContact O-CD1 3.38Å; F137-L141 WeakPolarHBondContact O-CG 3.44Å; F137-L141 PolarHBondContact O-N 3.45Å; F138-L141 PolarHBondContact O-N 3.18Å; L141-H144 CarbonylContact O-C 3.51Å; L141-H144 PolarHBondContact O-N 3.29Å; L141-S145 PolarHBondContact O-N 3.22Å; L141-I146 HydrophobicContact CB-CB 4.25Å; L141-I146 HydrophobicContact CD2-CB 3.71Å; L141-I146 HydrophobicContact CD2-CG1 3.96Å; L141-I146 HydrophobicContact CD2-CG2 3.74Å; L141-I146 PolarHBondContact O-N 3.23Å; L141-V148 HydrophobicContact CB-CG2 4.15Å; L141-V148 HydrophobicContact CD1-CG2 3.77Å; L141-V148 HydrophobicContact CG-CG2 4.46Å; L141-L281 HydrophobicContact CD1-CD1 4.32Å; L141-L281 HydrophobicContact CD2-CD1 3.96Å; L141-L281 HydrophobicContact CD2-CD2 3.82Å; L141-L281 HydrophobicContact CG-CD1 4.06Å; L141-L285 HydrophobicContact CD2-CD1 4.44Å
142Q98.6Very high98.6Very high57 Ų5738.7 Ų38.727%0.26620%0.201SC..Hα-helixtrans-64.5-41.8176.8170.556.62000112.2F138 D139 H144 S145 H170 N172F138-Q142 WeakPolarHBondContact O-CB 3.39Å; F138-Q142 PolarHBondContact O-N 3.11Å; D139-Q142 PolarHBondContact O-N 3.49Å; Q142-H144 PolarHBondContact O-N 2.79Å; Q142-H144 VanDerWaalsContact O-N 3.17Å; Q142-S145 PolarHBondContact O-N 3.5Å; Q142-H170 HydrophobicContact CB-CB 3.92Å; Q142-H170 HydrophobicContact CG-CB 3.79Å; Q142-N172 PolarHBondContact N-ND2 2.97Å; Q142-N172 PolarHBondContact OE1-OD1 2.99Å
143Q98.5Very high98.6Very high150 Ų15034 Ų3470%0.70118%0.18SC*.Hα-helixtrans-55.3-35.2178-179.1-176.90.900112.2D139D139-Q143 VanDerWaalsContact O-CB 3.32Å; D139-Q143 WeakPolarHBondContact O-CB 3.45Å; D139-Q143 PolarHBondContact O-N 2.8Å
144H98.6Very high98.5Very high59 Ų5933 Ų3327%0.27317%0.17SC..THydrogen-bonded Turntrans-100.27.9179-60.682.7000112.8A29 K140 L141 Q142 I146 L285A29-H144 HydrophobicContact CB-CB 4.37Å; K140-H144 PolarHBondContact O-N 2.77Å; K140-H144 PolarHBondContact O-ND1 3.14Å; L141-H144 CarbonylContact O-C 3.51Å; L141-H144 PolarHBondContact O-N 3.29Å; Q142-H144 PolarHBondContact O-N 2.79Å; Q142-H144 VanDerWaalsContact O-N 3.17Å; H144-I146 HydrophobicContact CB-CD1 3.89Å; H144-I146 HydrophobicContact CB-CG1 3.89Å; H144-I146 PolarHBondContact O-N 3.17Å; H144-L285 HydrophobicContact CB-CD1 4.36Å; H144-L285 HydrophobicContact CB-CD2 4.14Å
145S98.2Very high98.5Very high86 Ų8630.6 Ų30.660%0.60116%0.161SC*.THydrogen-bonded Turntrans51.936.3-177.5-580000113.6L141 Q142 P147L141-S145 PolarHBondContact O-N 3.22Å; Q142-S145 PolarHBondContact O-N 3.5Å; S145-P147 WeakPolarHBondContact O-CD 3.27Å
146I98.8Very high98.5Very high1 Ų126.4 Ų26.41%0.00514%0.141CC..  trans-71.3124.5178.3-53.4-52.9000108.8A29 L32 I34 L141 H144 V148 N172 L285A29-I146 HydrophobicContact CB-CD1 3.8Å; A29-I146 WeakPolarHBondContact O-CD1 3.3Å; L32-I146 HydrophobicContact CB-CD1 4.33Å; L32-I146 HydrophobicContact CB-CG2 4.29Å; L32-I146 HydrophobicContact CD2-CD1 4.48Å; L32-I146 HydrophobicContact CD2-CG1 4.44Å; L32-I146 HydrophobicContact CD2-CG2 4.05Å; L32-I146 HydrophobicContact CG-CG2 3.94Å; I34-I146 HydrophobicContact CG1-CG2 4.05Å; L141-I146 HydrophobicContact CB-CB 4.25Å; L141-I146 HydrophobicContact CD2-CB 3.71Å; L141-I146 HydrophobicContact CD2-CG1 3.96Å; L141-I146 HydrophobicContact CD2-CG2 3.74Å; L141-I146 PolarHBondContact O-N 3.23Å; H144-I146 HydrophobicContact CB-CD1 3.89Å; H144-I146 HydrophobicContact CB-CG1 3.89Å; H144-I146 PolarHBondContact O-N 3.17Å; I146-V148 PolarHBondContact O-N 2.94Å; I146-N172 WeakPolarHBondContact O-CB 3.14Å; I146-N172 PolarHBondContact O-ND2 3.25Å; I146-L285 HydrophobicContact CD1-CD2 3.81Å; I146-L285 HydrophobicContact CG1-CD1 4.03Å; I146-L285 HydrophobicContact CG1-CD2 4.13Å
147P98.6Very high98.5Very high18 Ų1823.6 Ų23.612%0.11713%0.126CC..  trans-61129.8176-20.631.5000111.2Q33 I34 S145 L215Q33-P147 HydrophobicContact CB-CB 4.28Å; I34-P147 PolarHBondContact N-O 2.8Å; S145-P147 WeakPolarHBondContact O-CD 3.27Å; P147-L215 HydrophobicContact CB-CD1 3.54Å; P147-L215 HydrophobicContact CB-CD2 4.15Å; P147-L215 HydrophobicContact CG-CD1 3.9Å; P147-L215 HydrophobicContact CG-CD2 3.64Å; P147-L215 HydrophobicContact CG-CG 4.41Å
148V98.8Very high98.5Very high0 Ų023.5 Ų23.50%013%0.126CC..EExtended strand (participates in β ladder)trans-118.3116175.4-176.60000109I34 T36 L141 I146 I150 N172 V173 K174I34-V148 HydrophobicContact CB-CB 4.46Å; I34-V148 HydrophobicContact CB-CG1 4.29Å; I34-V148 HydrophobicContact CB-CG2 4.2Å; I34-V148 HydrophobicContact CG1-CG2 4.28Å; I34-V148 HydrophobicContact CG2-CG1 4.31Å; T36-V148 HydrophobicContact CG2-CG1 4.33Å; L141-V148 HydrophobicContact CB-CG2 4.15Å; L141-V148 HydrophobicContact CD1-CG2 3.77Å; L141-V148 HydrophobicContact CG-CG2 4.46Å; I146-V148 PolarHBondContact O-N 2.94Å; V148-I150 HydrophobicContact CG1-CG1 4.06Å; V148-N172 PolarHBondContact N-O 2.62Å; V148-V173 HydrophobicContact CB-CG2 4.22Å; V148-V173 CarbonylContact O-C 3.18Å; V148-V173 WeakPolarHBondContact O-CA 3.42Å; V148-K174 PolarHBondContact O-N 3.45Å
149F98.6Very high98.5Very high0 Ų023.5 Ų23.50%013%0.126CC..EExtended strand (participates in β ladder)trans-105.2100.7176.5-171.3-100.2000109.5I34 I35 T36 F151 K174 V176 N208 Y211 F212I34-F149 PolarHBondContact O-N 2.84Å; I35-F149 WeakPolarHBondContact CA-O 3.38Å; I35-F149 HydrophobicContact CG1-CB 4.4Å; I35-F149 HydrophobicContact CG2-CD1 4.35Å; T36-F149 PolarHBondContact N-O 2.92Å; F149-F151 HydrophobicContact CD1-CB 3.87Å; F149-F151 HydrophobicContact CE1-CB 3.59Å; F149-F151 AromaticContact CE1-CD1 3.71Å; F149-F151 HydrophobicContact CE1-CD1 3.71Å; F149-F151 AromaticContact CE1-CG 3.77Å; F149-F151 HydrophobicContact CE1-CG 3.77Å; F149-K174 HydrophobicContact CD2-CB 4.2Å; F149-K174 HydrophobicContact CD2-CG 3.91Å; F149-K174 HydrophobicContact CE2-CG 4.13Å; F149-V176 HydrophobicContact CD2-CG2 4.44Å; F149-V176 HydrophobicContact CE1-CB 4.48Å; F149-V176 HydrophobicContact CE1-CG2 4.47Å; F149-V176 HydrophobicContact CE2-CB 4.22Å; F149-V176 HydrophobicContact CE2-CG2 3.39Å; F149-V176 HydrophobicContact CZ-CB 3.81Å; F149-V176 HydrophobicContact CZ-CG1 4.41Å; F149-V176 HydrophobicContact CZ-CG2 3.41Å; F149-V176 VanDerWaalsContact CZ-CG2 3.41Å; F149-N208 HydrophobicContact CE2-CB 4.38Å; F149-N208 HydrophobicContact CZ-CB 4.13Å; F149-Y211 HydrophobicContact CB-CE1 3.92Å; F149-Y211 AromaticContact CD2-CD1 3.69Å; F149-Y211 HydrophobicContact CD2-CD1 3.69Å; F149-Y211 AromaticContact CD2-CE1 3.35Å; F149-Y211 HydrophobicContact CD2-CE1 3.35Å; F149-Y211 HydrophobicContact CD2-CE2 4.49Å; F149-Y211 HydrophobicContact CD2-CG 4.39Å; F149-Y211 AromaticContact CD2-CZ 3.8Å; F149-Y211 AromaticContact CE2-CD1 3.96Å; F149-Y211 HydrophobicContact CE2-CD1 3.96Å; F149-Y211 HydrophobicContact CE2-CE1 4.11Å; F149-Y211 HydrophobicContact CE2-CG 4.45Å; F149-Y211 HydrophobicContact CG-CD1 4.49Å; F149-Y211 AromaticContact CG-CE1 3.91Å; F149-Y211 HydrophobicContact CG-CE1 3.91Å; F149-F212 HydrophobicContact CD1-CZ 4.09Å; F149-F212 AromaticContact CE1-CZ 3.99Å; F149-F212 HydrophobicContact CE1-CZ 3.99Å; F149-F212 HydrophobicContact CG-CZ 4.42Å; F149-F212 HydrophobicContact CZ-CZ 4.25Å
150I98.8Very high98.6Very high0 Ų021.8 Ų21.80%012%0.115CC..EExtended strand (participates in β ladder)trans-85.8112174.2-53.5-177.9000108.1T36 F38 L42 F138 V148 L159 I163 V173 K174 V175 V176T36-I150 HydrophobicContact CG2-CB 4.38Å; T36-I150 HydrophobicContact CG2-CG1 3.87Å; T36-I150 CarbonylContact O-C 3.56Å; T36-I150 WeakPolarHBondContact O-CA 3.26Å; F38-I150 HydrophobicContact CB-CG2 3.84Å; F38-I150 HydrophobicContact CD2-CG2 4.31Å; F38-I150 HydrophobicContact CG-CG2 4.49Å; L42-I150 HydrophobicContact CD1-CD1 4.06Å; L42-I150 HydrophobicContact CD1-CG1 4.36Å; F138-I150 HydrophobicContact CE1-CD1 4.21Å; F138-I150 HydrophobicContact CZ-CD1 4.24Å; V148-I150 HydrophobicContact CG1-CG1 4.06Å; I150-L159 HydrophobicContact CG2-CD1 3.9Å; I150-L159 HydrophobicContact CG2-CD2 4.48Å; I150-I163 HydrophobicContact CD1-CD1 4.23Å; I150-V173 HydrophobicContact CD1-CG1 3.54Å; I150-V173 HydrophobicContact CG1-CG1 3.94Å; I150-K174 PolarHBondContact N-O 2.65Å; I150-V175 HydrophobicContact CB-CG2 4.44Å; I150-V176 PolarHBondContact O-N 2.93Å
151F98.2Very high98.6Very high0 Ų022 Ų220%012%0.117CC..EExtended strand (participates in β ladder)trans-115.795.1-177.6-168.6-178.6000110.6T36 F149 V176 I196 K201 A205 M233T36-F151 PolarHBondContact O-N 2.77Å; F149-F151 HydrophobicContact CD1-CB 3.87Å; F149-F151 HydrophobicContact CE1-CB 3.59Å; F149-F151 AromaticContact CE1-CD1 3.71Å; F149-F151 HydrophobicContact CE1-CD1 3.71Å; F149-F151 AromaticContact CE1-CG 3.77Å; F149-F151 HydrophobicContact CE1-CG 3.77Å; F151-V176 WeakPolarHBondContact CA-O 3.43Å; F151-V176 HydrophobicContact CD2-CB 4.22Å; F151-V176 HydrophobicContact CD2-CG1 3.92Å; F151-V176 HydrophobicContact CE2-CG1 3.95Å; F151-I196 HydrophobicContact CD2-CG2 4.38Å; F151-I196 HydrophobicContact CE2-CD1 3.83Å; F151-I196 HydrophobicContact CE2-CG1 4.11Å; F151-I196 HydrophobicContact CE2-CG2 3.68Å; F151-I196 HydrophobicContact CZ-CG2 4.45Å; F151-K201 HydrophobicContact CD1-CB 4.4Å; F151-K201 HydrophobicContact CE1-CB 3.83Å; F151-K201 HydrophobicContact CE1-CG 4.38Å; F151-K201 WeakPolarHBondContact CE1-O 3.48Å; F151-K201 HydrophobicContact CE2-CG 4.38Å; F151-K201 HydrophobicContact CZ-CB 3.91Å; F151-K201 HydrophobicContact CZ-CG 4.17Å; F151-K201 VanDerWaalsContact CZ-O 3.29Å; F151-K201 WeakPolarHBondContact CZ-O 3.25Å; F151-K201 WeakPolarHBondContact O-CE 3.42Å; F151-K201 PolarHBondContact O-NZ 3.13Å; F151-A205 HydrophobicContact CE1-CB 4.07Å; F151-M233 HydrophobicContact CB-CG 4.39Å; F151-M233 HydrophobicContact CB-SD 3.91Å; F151-M233 HydrophobicContact CD1-CB 4.01Å; F151-M233 HydrophobicContact CD1-CG 3.79Å; F151-M233 HydrophobicContact CD1-SD 4.38Å; F151-M233 HydrophobicContact CE1-CG 4.45Å; F151-M233 HydrophobicContact CG-CG 4.36Å; F151-M233 HydrophobicContact CG-SD 4.39Å
152S98.3Very high98.6Very high0 Ų022.4 Ų22.40%012%0.119CC..EExtended strand (participates in β ladder)trans-112.2137.2-170.8178.40000112.4G154 V176 S177S152-G154 PolarHBondContact O-N 3.44Å; S152-G154 PolarHBondContact OG-N 3.46Å; S152-V176 PolarHBondContact N-O 3.49Å; S152-S177 VanDerWaalsContact O-CA 3.24Å; S152-S177 WeakPolarHBondContact O-CA 2.98Å; S152-S177 WeakPolarHBondContact O-CB 3.48Å; S152-S177 PolarHBondContact O-OG 3.01Å
153A97.7Very high98.6Very high10 Ų1019.7 Ų19.78%0.08311%0.106CC..EExtended strand (participates in β ladder)trans-80.55.7166.200000112.9Y102 N178 I196Y102-A153 WeakPolarHBondContact CE1-O 3.45Å; Y102-A153 PolarHBondContact OH-O 2.98Å; A153-N178 PolarHBondContact O-ND2 3.14Å; A153-N178 VanDerWaalsContact O-ND2 3.09Å; A153-I196 HydrophobicContact CB-CG2 4.15Å
154G97.9Very high98.6Very high1 Ų117.7 Ų17.71%0.019%0.092CC..EExtended strand (participates in β ladder)trans-77.9-146.3178.100000113.5S152 S177 N178S152-G154 PolarHBondContact O-N 3.44Å; S152-G154 PolarHBondContact OG-N 3.46Å; G154-S177 PolarHBondContact O-OG 2.84Å; G154-N178 WeakPolarHBondContact O-CB 3.15Å; G154-N178 PolarHBondContact O-ND2 2.91Å
155I98.8Very high98.6Very high0 Ų018.7 Ų18.70%010%0.097CC..EExtended strand (participates in β ladder)trans-110.4119.5175.2-60.3176.4000108.9C55 I59 L109 V158 L159 M180 F191C55-I155 HydrophobicContact CB-CB 4.31Å; I59-I155 HydrophobicContact CG1-CD1 3.94Å; L109-I155 HydrophobicContact CD1-CD1 4.06Å; I155-V158 HydrophobicContact CB-CB 4.19Å; I155-V158 HydrophobicContact CB-CG2 4.08Å; I155-V158 HydrophobicContact CG2-CB 4.19Å; I155-V158 HydrophobicContact CG2-CG2 3.74Å; I155-V158 PolarHBondContact O-N 2.87Å; I155-L159 WeakPolarHBondContact O-CB 3.39Å; I155-L159 PolarHBondContact O-N 3.04Å; I155-M180 HydrophobicContact CD1-CE 4Å; I155-M180 HydrophobicContact CG2-CE 3.75Å; I155-M180 HydrophobicContact CG2-CG 4.02Å; I155-M180 HydrophobicContact CG2-SD 4.35Å; I155-F191 HydrophobicContact CG1-CE1 4.25Å; I155-F191 HydrophobicContact CG2-CE1 4.25Å
156G98.7Very high98.6Very high0 Ų016 Ų160%08%0.08CC..Hα-helixtrans-60.5-50.2-173.600000113.8V158 L159 E160 N178G156-V158 PolarHBondContact O-N 2.95Å; G156-L159 WeakPolarHBondContact O-CB 3.29Å; G156-L159 PolarHBondContact O-N 2.81Å; G156-E160 WeakPolarHBondContact O-CG 3.39Å; G156-E160 PolarHBondContact O-N 3.47Å; G156-N178 PolarHBondContact N-O 2.92Å
157D98.9Very high98.6Very high19 Ų1918.4 Ų18.410%0.10211%0.105CC..Hα-helixtrans-61.7-33.8-178.2-56.7-110.2000112.7L119 E161 F179 M180L119-D157 HydrophobicContact CD1-CB 3.7Å; D157-E161 WeakPolarHBondContact O-CB 3.46Å; D157-E161 PolarHBondContact O-N 3.24Å; D157-F179 WeakPolarHBondContact OD2-CA 3.49Å; D157-M180 WeakPolarHBondContact OD2-CB 3.35Å; D157-M180 PolarHBondContact OD2-N 3.36Å
158V98.9Very high98.6Very high0 Ų017.7 Ų17.70%010%0.1CC..Hα-helixtrans-72.8-49.3177.1176.80000110.2C55 I58 I59 L119 V123 I155 G156 E160 E161 V162C55-V158 HydrophobicContact CB-CB 4.33Å; C55-V158 HydrophobicContact CB-CG1 4.14Å; I58-V158 HydrophobicContact CB-CG1 4.04Å; I58-V158 HydrophobicContact CD1-CG1 3.68Å; I58-V158 HydrophobicContact CG1-CG1 4.46Å; I58-V158 HydrophobicContact CG2-CG1 3.99Å; I59-V158 HydrophobicContact CD1-CG2 3.62Å; I59-V158 HydrophobicContact CG1-CG2 3.77Å; L119-V158 HydrophobicContact CD2-CG2 4.42Å; V123-V158 HydrophobicContact CG2-CG1 4.02Å; I155-V158 HydrophobicContact CB-CB 4.19Å; I155-V158 HydrophobicContact CB-CG2 4.08Å; I155-V158 HydrophobicContact CG2-CB 4.19Å; I155-V158 HydrophobicContact CG2-CG2 3.74Å; I155-V158 PolarHBondContact O-N 2.87Å; G156-V158 PolarHBondContact O-N 2.95Å; V158-E160 VanDerWaalsContact C-N 3.32Å; V158-E160 PolarHBondContact O-N 3.25Å; V158-E161 PolarHBondContact O-N 3.36Å; V158-E161 VanDerWaalsContact O-N 3.12Å; V158-V162 HydrophobicContact CG1-CG2 4.48Å; V158-V162 WeakPolarHBondContact O-CG2 3.31Å; V158-V162 PolarHBondContact O-N 2.86Å
159L98.9Very high98.6Very high0 Ų020.8 Ų20.80%011%0.112CC..Hα-helixtrans-52.5-52.8175.9-179.2166.9000110.5F38 I150 I155 G156 E161 V162 I163 V175F38-L159 HydrophobicContact CB-CD1 3.55Å; F38-L159 HydrophobicContact CB-CG 4.24Å; F38-L159 HydrophobicContact CD1-CB 4.33Å; F38-L159 HydrophobicContact CD1-CD1 3.84Å; F38-L159 HydrophobicContact CD1-CG 3.73Å; F38-L159 HydrophobicContact CD2-CD1 3.96Å; F38-L159 HydrophobicContact CD2-CD2 4.22Å; F38-L159 HydrophobicContact CD2-CG 3.73Å; F38-L159 HydrophobicContact CE1-CB 4.34Å; F38-L159 HydrophobicContact CE1-CG 3.94Å; F38-L159 HydrophobicContact CE2-CD2 4.35Å; F38-L159 HydrophobicContact CE2-CG 3.96Å; F38-L159 HydrophobicContact CG-CD1 3.49Å; F38-L159 VanDerWaalsContact CG-CD1 3.49Å; F38-L159 HydrophobicContact CG-CG 3.61Å; F38-L159 HydrophobicContact CZ-CG 4.05Å; I150-L159 HydrophobicContact CG2-CD1 3.9Å; I150-L159 HydrophobicContact CG2-CD2 4.48Å; I155-L159 WeakPolarHBondContact O-CB 3.39Å; I155-L159 PolarHBondContact O-N 3.04Å; G156-L159 WeakPolarHBondContact O-CB 3.29Å; G156-L159 PolarHBondContact O-N 2.81Å; L159-E161 VanDerWaalsContact C-N 3.26Å; L159-E161 PolarHBondContact O-N 2.82Å; L159-V162 WeakPolarHBondContact O-CB 3.47Å; L159-V162 PolarHBondContact O-N 2.81Å; L159-V162 VanDerWaalsContact O-N 3.1Å; L159-I163 HydrophobicContact CD2-CD1 3.86Å; L159-I163 HydrophobicContact CD2-CG1 4.23Å; L159-I163 WeakPolarHBondContact O-CG1 3.44Å; L159-I163 PolarHBondContact O-N 2.92Å; L159-I163 VanDerWaalsContact O-N 3.08Å; L159-V175 HydrophobicContact CD1-CG1 4.1Å; L159-V175 HydrophobicContact CD2-CB 4.46Å; L159-V175 HydrophobicContact CD2-CG1 3.82Å; L159-V175 HydrophobicContact CD2-CG2 3.72Å
160E98.9Very high98.6Very high41 Ų4122.5 Ų22.519%0.19212%0.12CC..Hα-helixtrans-56.8-41.7179.5-75.7-159.516100112G156 V158 I163 R164 Y169 V175 F179G156-E160 WeakPolarHBondContact O-CG 3.39Å; G156-E160 PolarHBondContact O-N 3.47Å; V158-E160 VanDerWaalsContact C-N 3.32Å; V158-E160 PolarHBondContact O-N 3.25Å; E160-I163 WeakPolarHBondContact O-CG1 3.33Å; E160-R164 WeakPolarHBondContact O-CB 3.34Å; E160-R164 PolarHBondContact O-N 3.36Å; E160-R164 PolarHBondContact O-NH1 3.29Å; E160-R164 IonicContact OE2-NH2 3.93Å; E160-R164 PolarHBondContact OE2-NH2 2.98Å; E160-Y169 HydrophobicContact CB-CD1 4.26Å; E160-Y169 HydrophobicContact CB-CE1 3.71Å; E160-Y169 VanDerWaalsContact CD-CE1 3.47Å; E160-Y169 HydrophobicContact CG-CD1 4.45Å; E160-Y169 HydrophobicContact CG-CE1 3.48Å; E160-Y169 VanDerWaalsContact CG-CE1 3.48Å; E160-Y169 PolarHBondContact OE1-OH 3.18Å; E160-V175 HydrophobicContact CG-CB 4.44Å; E160-V175 HydrophobicContact CG-CG1 4.44Å; E160-V175 HydrophobicContact CG-CG2 4.28Å; E160-F179 HydrophobicContact CG-CE1 4.14Å; E160-F179 HydrophobicContact CG-CZ 4.41Å
161E98.9Very high98.6Very high21 Ų2128.3 Ų28.310%0.09816%0.158CC..Hα-helixtrans-69.1-35.1178.7-172.861.4-161.200112.3K120 V123 D157 V158 L159 R164 Q165K120-E161 WeakPolarHBondContact CB-OE1 3.4Å; K120-E161 VanDerWaalsContact CG-OE1 3.3Å; K120-E161 WeakPolarHBondContact CG-OE1 3.26Å; V123-E161 HydrophobicContact CB-CB 4.49Å; V123-E161 HydrophobicContact CB-CG 3.91Å; V123-E161 HydrophobicContact CG1-CG 4.19Å; V123-E161 HydrophobicContact CG2-CB 4.02Å; V123-E161 HydrophobicContact CG2-CG 3.9Å; D157-E161 WeakPolarHBondContact O-CB 3.46Å; D157-E161 PolarHBondContact O-N 3.24Å; V158-E161 PolarHBondContact O-N 3.36Å; V158-E161 VanDerWaalsContact O-N 3.12Å; L159-E161 VanDerWaalsContact C-N 3.26Å; L159-E161 PolarHBondContact O-N 2.82Å; E161-R164 PolarHBondContact O-N 3.08Å; E161-R164 IonicContact OE2-CZ 2.71Å; E161-R164 IonicContact OE2-NH1 3.59Å; E161-R164 PolarHBondContact OE2-NH1 3.08Å; E161-Q165 HydrophobicContact CG-CG 4.42Å; E161-Q165 WeakPolarHBondContact O-CB 3.35Å; E161-Q165 WeakPolarHBondContact O-CG 3.29Å; E161-Q165 PolarHBondContact O-N 2.74Å; E161-Q165 WeakPolarHBondContact OE1-CG 3.41Å; E161-Q165 PolarHBondContact OE1-NE2 3.31Å
162V98.9Very high98.6Very high8 Ų829.3 Ų29.35%0.04816%0.163CC..Hα-helixtrans-59.6-54.5173.1174.30000110.6F38 I58 V123 V128 L130 V158 L159 R164 Q165 A166F38-V162 HydrophobicContact CZ-CB 4.09Å; F38-V162 HydrophobicContact CZ-CG1 3.86Å; I58-V162 HydrophobicContact CD1-CG2 3.86Å; V123-V162 HydrophobicContact CG1-CB 4.41Å; V123-V162 HydrophobicContact CG1-CG2 3.72Å; V123-V162 HydrophobicContact CG2-CG2 4.42Å; V128-V162 HydrophobicContact CG1-CG1 4.23Å; V128-V162 HydrophobicContact CG1-CG2 4.11Å; V128-V162 HydrophobicContact CG2-CG1 4.07Å; V128-V162 HydrophobicContact CG2-CG2 4.18Å; L130-V162 HydrophobicContact CD2-CG1 4.23Å; V158-V162 HydrophobicContact CG1-CG2 4.48Å; V158-V162 WeakPolarHBondContact O-CG2 3.31Å; V158-V162 PolarHBondContact O-N 2.86Å; L159-V162 WeakPolarHBondContact O-CB 3.47Å; L159-V162 PolarHBondContact O-N 2.81Å; L159-V162 VanDerWaalsContact O-N 3.1Å; V162-R164 VanDerWaalsContact C-N 3.3Å; V162-R164 PolarHBondContact O-N 3.3Å; V162-Q165 PolarHBondContact O-N 3.08Å; V162-A166 WeakPolarHBondContact O-CB 3.19Å; V162-A166 PolarHBondContact O-N 3.1Å
163I98.8Very high98.7Very high0 Ų029.9 Ų29.90%017%0.167CC..Hα-helixtrans-70.8-26.4-17857.5170.6000112.7F38 I150 L159 E160 G167 V168 Y169 V173 V175F38-I163 HydrophobicContact CE2-CG2 3.66Å; F38-I163 HydrophobicContact CZ-CG2 4.3Å; I150-I163 HydrophobicContact CD1-CD1 4.23Å; L159-I163 HydrophobicContact CD2-CD1 3.86Å; L159-I163 HydrophobicContact CD2-CG1 4.23Å; L159-I163 WeakPolarHBondContact O-CG1 3.44Å; L159-I163 PolarHBondContact O-N 2.92Å; L159-I163 VanDerWaalsContact O-N 3.08Å; E160-I163 WeakPolarHBondContact O-CG1 3.33Å; I163-G167 PolarHBondContact O-N 2.77Å; I163-V168 HydrophobicContact CB-CG2 4.04Å; I163-V168 HydrophobicContact CG2-CG2 4.33Å; I163-V168 PolarHBondContact O-N 2.91Å; I163-Y169 HydrophobicContact CD1-CD1 3.95Å; I163-Y169 HydrophobicContact CD1-CD2 3.56Å; I163-Y169 HydrophobicContact CD1-CE1 4.35Å; I163-Y169 HydrophobicContact CD1-CE2 3.97Å; I163-Y169 HydrophobicContact CD1-CG 3.53Å; I163-Y169 HydrophobicContact CG1-CD1 3.99Å; I163-Y169 HydrophobicContact CG1-CD2 4.35Å; I163-Y169 HydrophobicContact CG1-CG 3.81Å; I163-Y169 PolarHBondContact O-N 3.4Å; I163-V173 HydrophobicContact CD1-CG1 4.25Å; I163-V175 HydrophobicContact CD1-CG2 4.16Å
164R98.8Very high98.7Very high108 Ų10834 Ų3441%0.40818%0.183SC..Hα-helixtrans-69.5-46.6173.7-175.5-177.9-61.51094.8111.7E160 E161 V162 A166 G167 Y169E160-R164 WeakPolarHBondContact O-CB 3.34Å; E160-R164 PolarHBondContact O-N 3.36Å; E160-R164 PolarHBondContact O-NH1 3.29Å; E160-R164 IonicContact OE2-NH2 3.93Å; E160-R164 PolarHBondContact OE2-NH2 2.98Å; E161-R164 PolarHBondContact O-N 3.08Å; E161-R164 IonicContact OE2-CZ 2.71Å; E161-R164 IonicContact OE2-NH1 3.59Å; E161-R164 PolarHBondContact OE2-NH1 3.08Å; V162-R164 VanDerWaalsContact C-N 3.3Å; V162-R164 PolarHBondContact O-N 3.3Å; R164-A166 VanDerWaalsContact C-N 3.28Å; R164-A166 PolarHBondContact O-N 3.08Å; R164-G167 PolarHBondContact O-N 3.28Å; R164-G167 VanDerWaalsContact O-N 3.09Å; R164-Y169 HydrophobicContact CB-CD1 4.41Å
165Q98.8Very high98.7Very high79 Ų7934.3 Ų34.337%0.36919%0.185SC..Hα-helixtrans-66.9-32176.5-71-173.625.300112.2K120 E161 V162 G167K120-Q165 PolarHBondContact O-NE2 3.36Å; E161-Q165 HydrophobicContact CG-CG 4.42Å; E161-Q165 WeakPolarHBondContact O-CB 3.35Å; E161-Q165 WeakPolarHBondContact O-CG 3.29Å; E161-Q165 PolarHBondContact O-N 2.74Å; E161-Q165 WeakPolarHBondContact OE1-CG 3.41Å; E161-Q165 PolarHBondContact OE1-NE2 3.31Å; V162-Q165 PolarHBondContact O-N 3.08Å; Q165-G167 PolarHBondContact O-N 3.03Å
166A98.6Very high98.7Very high30 Ų3035.1 Ų35.125%0.24819%0.189CC..THydrogen-bonded Turntrans-73.5-6.8172.700000113.9L130 Y134 V162 R164 V168L130-A166 HydrophobicContact CD1-CB 3.75Å; Y134-A166 HydrophobicContact CE2-CB 3.9Å; V162-A166 WeakPolarHBondContact O-CB 3.19Å; V162-A166 PolarHBondContact O-N 3.1Å; R164-A166 VanDerWaalsContact C-N 3.28Å; R164-A166 PolarHBondContact O-N 3.08Å; A166-V168 VanDerWaalsContact C-N 3.34Å; A166-V168 HydrophobicContact CB-CG2 4Å
167G98.7Very high98.6Very high51 Ų5135.6 Ų35.653%0.52619%0.193SC..THydrogen-bonded Turntrans76.416.6177.200000115.1I163 R164 Q165 H170I163-G167 PolarHBondContact O-N 2.77Å; R164-G167 PolarHBondContact O-N 3.28Å; R164-G167 VanDerWaalsContact O-N 3.09Å; Q165-G167 PolarHBondContact O-N 3.03Å; G167-H170 PolarHBondContact O-CE1 3.4Å
168V98.8Very high98.6Very high3 Ų334.9 Ų34.92%0.01819%0.189CC..  trans-118.98.7-172.1-64.10000113.9L130 Y134 F138 I163 A166 H170L130-V168 HydrophobicContact CD1-CG2 4.42Å; Y134-V168 HydrophobicContact CD2-CG1 3.96Å; Y134-V168 HydrophobicContact CD2-CG2 4.2Å; Y134-V168 HydrophobicContact CE2-CG1 3.92Å; Y134-V168 HydrophobicContact CE2-CG2 4.38Å; F138-V168 HydrophobicContact CB-CB 3.65Å; F138-V168 HydrophobicContact CB-CG1 3.87Å; F138-V168 HydrophobicContact CD1-CB 4.31Å; F138-V168 HydrophobicContact CD2-CB 3.73Å; F138-V168 HydrophobicContact CD2-CG1 4.18Å; F138-V168 HydrophobicContact CD2-CG2 3.68Å; F138-V168 HydrophobicContact CE2-CB 4.46Å; F138-V168 HydrophobicContact CE2-CG2 3.95Å; F138-V168 HydrophobicContact CG-CB 3.65Å; F138-V168 HydrophobicContact CG-CG1 4.26Å; F138-V168 HydrophobicContact CG-CG2 4.05Å; I163-V168 HydrophobicContact CB-CG2 4.04Å; I163-V168 HydrophobicContact CG2-CG2 4.33Å; I163-V168 PolarHBondContact O-N 2.91Å; A166-V168 VanDerWaalsContact C-N 3.34Å; A166-V168 HydrophobicContact CB-CG2 4Å; V168-H170 PolarHBondContact O-N 2.92Å
169Y98.8Very high98.6Very high65 Ų6537.2 Ų37.226%0.25520%0.199SC..  trans-79.669.5172.1-159.8179.4000111.4E160 I163 R164 V173 V175E160-Y169 HydrophobicContact CB-CD1 4.26Å; E160-Y169 HydrophobicContact CB-CE1 3.71Å; E160-Y169 VanDerWaalsContact CD-CE1 3.47Å; E160-Y169 HydrophobicContact CG-CD1 4.45Å; E160-Y169 HydrophobicContact CG-CE1 3.48Å; E160-Y169 VanDerWaalsContact CG-CE1 3.48Å; E160-Y169 PolarHBondContact OE1-OH 3.18Å; I163-Y169 HydrophobicContact CD1-CD1 3.95Å; I163-Y169 HydrophobicContact CD1-CD2 3.56Å; I163-Y169 HydrophobicContact CD1-CE1 4.35Å; I163-Y169 HydrophobicContact CD1-CE2 3.97Å; I163-Y169 HydrophobicContact CD1-CG 3.53Å; I163-Y169 HydrophobicContact CG1-CD1 3.99Å; I163-Y169 HydrophobicContact CG1-CD2 4.35Å; I163-Y169 HydrophobicContact CG1-CG 3.81Å; I163-Y169 PolarHBondContact O-N 3.4Å; R164-Y169 HydrophobicContact CB-CD1 4.41Å; Y169-V173 HydrophobicContact CD2-CB 3.96Å; Y169-V173 HydrophobicContact CD2-CG1 4.07Å; Y169-V173 HydrophobicContact CE2-CB 4.08Å; Y169-V173 HydrophobicContact CE2-CG1 4.01Å; Y169-V175 HydrophobicContact CE2-CG2 4.01Å
170H98.6Very high98.6Very high37 Ų3737.2 Ų37.217%0.17120%0.199CC..  trans-77.6160.5-176.9-61.9-44000112.4D139 Q142 G167 V168 N172 V173D139-H170 IonicContact OD1-CD2 2.57Å; D139-H170 IonicContact OD1-CE1 3.66Å; D139-H170 IonicContact OD1-NE2 2.88Å; D139-H170 PolarHBondContact OD1-NE2 2.91Å; Q142-H170 HydrophobicContact CB-CB 3.92Å; Q142-H170 HydrophobicContact CG-CB 3.79Å; G167-H170 PolarHBondContact O-CE1 3.4Å; V168-H170 PolarHBondContact O-N 2.92Å; H170-N172 WeakPolarHBondContact CB-OD1 3.48Å; H170-N172 PolarHBondContact O-N 3.44Å; H170-N172 VanDerWaalsContact O-N 3.13Å; H170-V173 HydrophobicContact CB-CG2 4.4Å; H170-V173 WeakPolarHBondContact O-CB 3.48Å; H170-V173 PolarHBondContact O-N 3.2Å
171P98.3Very high98.6Very high122 Ų12237.7 Ų37.779%0.79220%0.203SC*.THydrogen-bonded Turntrans-60.3-22.1-178.9-26.135.6000115.7V173P171-V173 PolarHBondContact O-N 3.13Å
172N98.4Very high98.6Very high21 Ų2137.8 Ų37.811%0.11220%0.203CC..THydrogen-bonded Turntrans-77.7-7.8175.770.2-37.9000113.6Q142 I146 V148 H170Q142-N172 PolarHBondContact N-ND2 2.97Å; Q142-N172 PolarHBondContact OE1-OD1 2.99Å; I146-N172 WeakPolarHBondContact O-CB 3.14Å; I146-N172 PolarHBondContact O-ND2 3.25Å; V148-N172 PolarHBondContact N-O 2.62Å; H170-N172 WeakPolarHBondContact CB-OD1 3.48Å; H170-N172 PolarHBondContact O-N 3.44Å; H170-N172 VanDerWaalsContact O-N 3.13Å
173V98.7Very high98.5Very high12 Ų1240.2 Ų40.27%0.07322%0.216CC..EExtended strand (participates in β ladder)trans-92.7121.1-178.9-176.20000110.4F138 V148 I150 I163 Y169 H170 P171 V175F138-V173 HydrophobicContact CD1-CG2 4.03Å; F138-V173 HydrophobicContact CE1-CG2 4.05Å; V148-V173 HydrophobicContact CB-CG2 4.22Å; V148-V173 CarbonylContact O-C 3.18Å; V148-V173 WeakPolarHBondContact O-CA 3.42Å; I150-V173 HydrophobicContact CD1-CG1 3.54Å; I150-V173 HydrophobicContact CG1-CG1 3.94Å; I163-V173 HydrophobicContact CD1-CG1 4.25Å; Y169-V173 HydrophobicContact CD2-CB 3.96Å; Y169-V173 HydrophobicContact CD2-CG1 4.07Å; Y169-V173 HydrophobicContact CE2-CB 4.08Å; Y169-V173 HydrophobicContact CE2-CG1 4.01Å; H170-V173 HydrophobicContact CB-CG2 4.4Å; H170-V173 WeakPolarHBondContact O-CB 3.48Å; H170-V173 PolarHBondContact O-N 3.2Å; P171-V173 PolarHBondContact O-N 3.13Å; V173-V175 HydrophobicContact CG1-CG2 4.36Å
174K98.2Very high98.4Very high97 Ų9750 Ų5042%0.42226%0.262SS..EExtended strand (participates in β ladder)trans-108.2125.8170.8179.164177.7-179.40109.3V148 F149 I150 Y211V148-K174 PolarHBondContact O-N 3.45Å; F149-K174 HydrophobicContact CD2-CB 4.2Å; F149-K174 HydrophobicContact CD2-CG 3.91Å; F149-K174 HydrophobicContact CE2-CG 4.13Å; I150-K174 PolarHBondContact N-O 2.65Å; K174-Y211 HydrophobicContact CB-CE2 3.89Å; K174-Y211 HydrophobicContact CG-CD2 4.26Å; K174-Y211 HydrophobicContact CG-CE2 3.98Å
175V98.4Very high98.3Very high7 Ų750.3 Ų50.34%0.04228%0.276CS..EExtended strand (participates in β ladder)trans-102.5130.5175.3-179.40000110.4I150 L159 E160 I163 Y169 V173 F179I150-V175 HydrophobicContact CB-CG2 4.44Å; L159-V175 HydrophobicContact CD1-CG1 4.1Å; L159-V175 HydrophobicContact CD2-CB 4.46Å; L159-V175 HydrophobicContact CD2-CG1 3.82Å; L159-V175 HydrophobicContact CD2-CG2 3.72Å; E160-V175 HydrophobicContact CG-CB 4.44Å; E160-V175 HydrophobicContact CG-CG1 4.44Å; E160-V175 HydrophobicContact CG-CG2 4.28Å; I163-V175 HydrophobicContact CD1-CG2 4.16Å; Y169-V175 HydrophobicContact CE2-CG2 4.01Å; V173-V175 HydrophobicContact CG1-CG2 4.36Å; V175-F179 HydrophobicContact CB-CZ 4.27Å; V175-F179 HydrophobicContact CG1-CE2 4.35Å; V175-F179 HydrophobicContact CG1-CZ 3.87Å
176V97.9Very high98.3Very high17 Ų1747.6 Ų47.610%0.10327%0.269CS..EExtended strand (participates in β ladder)trans-125.5117.4168.1174.50000108.2F149 I150 F151 S152 I196F149-V176 HydrophobicContact CD2-CG2 4.44Å; F149-V176 HydrophobicContact CE1-CB 4.48Å; F149-V176 HydrophobicContact CE1-CG2 4.47Å; F149-V176 HydrophobicContact CE2-CB 4.22Å; F149-V176 HydrophobicContact CE2-CG2 3.39Å; F149-V176 HydrophobicContact CZ-CB 3.81Å; F149-V176 HydrophobicContact CZ-CG1 4.41Å; F149-V176 HydrophobicContact CZ-CG2 3.41Å; F149-V176 VanDerWaalsContact CZ-CG2 3.41Å; I150-V176 PolarHBondContact O-N 2.93Å; F151-V176 WeakPolarHBondContact CA-O 3.43Å; F151-V176 HydrophobicContact CD2-CB 4.22Å; F151-V176 HydrophobicContact CD2-CG1 3.92Å; F151-V176 HydrophobicContact CE2-CG1 3.95Å; S152-V176 PolarHBondContact N-O 3.49Å; V176-I196 HydrophobicContact CG1-CD1 3.93Å
177S98.2Very high98.3Very high10 Ų1047.9 Ų47.97%0.0727%0.267CS..EExtended strand (participates in β ladder)trans-162.4-176.5-176.7-164.80000111.3S152 G154 F179S152-S177 VanDerWaalsContact O-CA 3.24Å; S152-S177 WeakPolarHBondContact O-CA 2.98Å; S152-S177 WeakPolarHBondContact O-CB 3.48Å; S152-S177 PolarHBondContact O-OG 3.01Å; G154-S177 PolarHBondContact O-OG 2.84Å; S177-F179 VanDerWaalsContact O-CD2 3.3Å; S177-F179 WeakPolarHBondContact O-CD2 3.42Å; S177-F179 PolarHBondContact O-N 3.47Å; S177-F179 VanDerWaalsContact O-N 3.1Å
178N98.4Very high98.3Very high3 Ų345.7 Ų45.72%0.01624%0.244CC..EExtended strand (participates in β ladder)trans-76.294173.3-54.9-65.8000109.7A153 G154 G156 F191 I196A153-N178 PolarHBondContact O-ND2 3.14Å; A153-N178 VanDerWaalsContact O-ND2 3.09Å; G154-N178 WeakPolarHBondContact O-CB 3.15Å; G154-N178 PolarHBondContact O-ND2 2.91Å; G156-N178 PolarHBondContact N-O 2.92Å; N178-F191 HydrophobicContact CB-CD1 3.91Å; N178-F191 HydrophobicContact CB-CE1 4.39Å; N178-I196 PolarHBondContact ND2-O 3.32Å; N178-I196 PolarHBondContact OD1-N 3.41Å; N178-I196 PolarHBondContact OD1-O 2.96Å
179F98.6Very high98.3Very high49 Ų4951 Ų5122%0.21527%0.266CS..  trans-79.5136.4176.9-76.6-86000111.2D157 E160 V175 S177 F191 K192D157-F179 WeakPolarHBondContact OD2-CA 3.49Å; E160-F179 HydrophobicContact CG-CE1 4.14Å; E160-F179 HydrophobicContact CG-CZ 4.41Å; V175-F179 HydrophobicContact CB-CZ 4.27Å; V175-F179 HydrophobicContact CG1-CE2 4.35Å; V175-F179 HydrophobicContact CG1-CZ 3.87Å; S177-F179 VanDerWaalsContact O-CD2 3.3Å; S177-F179 WeakPolarHBondContact O-CD2 3.42Å; S177-F179 PolarHBondContact O-N 3.47Å; S177-F179 VanDerWaalsContact O-N 3.1Å; F179-F191 CarbonylContact O-C 3.52Å; F179-F191 WeakPolarHBondContact O-CA 3.43Å; F179-K192 HydrophobicContact CB-CD 4.44Å; F179-K192 PolarHBondContact O-N 3.05Å
180M98.6Very high98.2Very high0 Ų048.8 Ų48.80%026%0.263CS..EExtended strand (participates in β ladder)trans-66142.9175.8-71.4-175170.500110.7I59 L119 I155 D157 F182 L188 F191 K192I59-M180 HydrophobicContact CD1-CE 4.45Å; I59-M180 HydrophobicContact CG1-CE 4.25Å; L119-M180 HydrophobicContact CD1-SD 4.47Å; L119-M180 HydrophobicContact CD2-SD 4.48Å; I155-M180 HydrophobicContact CD1-CE 4Å; I155-M180 HydrophobicContact CG2-CE 3.75Å; I155-M180 HydrophobicContact CG2-CG 4.02Å; I155-M180 HydrophobicContact CG2-SD 4.35Å; D157-M180 WeakPolarHBondContact OD2-CB 3.35Å; D157-M180 PolarHBondContact OD2-N 3.36Å; M180-F182 HydrophobicContact CB-CD2 4.28Å; M180-F182 HydrophobicContact CB-CE1 4.33Å; M180-F182 HydrophobicContact CB-CE2 3.47Å; M180-F182 VanDerWaalsContact CB-CE2 3.47Å; M180-F182 HydrophobicContact CB-CZ 3.49Å; M180-F182 VanDerWaalsContact CB-CZ 3.49Å; M180-F182 HydrophobicContact CG-CZ 4.22Å; M180-F182 HydrophobicContact SD-CE1 4.24Å; M180-F182 HydrophobicContact SD-CZ 3.7Å; M180-L188 HydrophobicContact CB-CD1 3.63Å; M180-L188 HydrophobicContact CE-CD2 4.16Å; M180-L188 HydrophobicContact CG-CD1 3.64Å; M180-L188 HydrophobicContact SD-CD1 3.9Å; M180-L188 HydrophobicContact SD-CD2 4.34Å; M180-F191 HydrophobicContact CE-CZ 4.26Å; M180-F191 HydrophobicContact CG-CD1 4.33Å; M180-F191 HydrophobicContact CG-CE1 3.75Å; M180-F191 HydrophobicContact CG-CZ 4.01Å; M180-K192 VanDerWaalsContact O-CE 3.27Å; M180-K192 WeakPolarHBondContact O-CE 3.38Å
181D98.6Very high98.2Very high51 Ų5149.1 Ų49.127%0.27326%0.264SS..EExtended strand (participates in β ladder)trans-106.1129.5168.2-161.623.9000110K189 G190 K192D181-K189 HydrophobicContact CB-CG 4.44Å; D181-K189 WeakPolarHBondContact O-CG 3.42Å; D181-K189 PolarHBondContact O-N 3.1Å; D181-K189 WeakPolarHBondContact OD2-CE 3.47Å; D181-K189 IonicContact OD2-NZ 3.47Å; D181-K189 PolarHBondContact OD2-NZ 3.24Å; D181-G190 PolarHBondContact N-O 3.33Å; D181-G190 PolarHBondContact O-N 2.98Å; D181-K192 HydrophobicContact CB-CG 3.75Å; D181-K192 VanDerWaalsContact OD1-CE 3.29Å; D181-K192 WeakPolarHBondContact OD1-CE 3.39Å
182F98.5Very high98.1Very high24 Ų2448.8 Ų48.811%0.10525%0.25CS..EExtended strand (participates in β ladder)trans-113.3147.2-175.5-61.1-85000109.9K116 L119 M180 G186 V187 L188 K189K116-F182 HydrophobicContact CB-CD1 3.7Å; K116-F182 HydrophobicContact CB-CD2 4.23Å; K116-F182 HydrophobicContact CB-CE1 3.54Å; K116-F182 HydrophobicContact CB-CE2 4.06Å; K116-F182 HydrophobicContact CB-CG 4.06Å; K116-F182 HydrophobicContact CB-CZ 3.73Å; K116-F182 HydrophobicContact CD-CD2 3.77Å; K116-F182 HydrophobicContact CD-CE2 3.75Å; K116-F182 HydrophobicContact CD-CG 4.27Å; K116-F182 HydrophobicContact CD-CZ 4.26Å; K116-F182 HydrophobicContact CG-CD1 4.46Å; K116-F182 HydrophobicContact CG-CD2 4.16Å; K116-F182 HydrophobicContact CG-CE1 4.13Å; K116-F182 HydrophobicContact CG-CE2 3.77Å; K116-F182 HydrophobicContact CG-CG 4.49Å; K116-F182 HydrophobicContact CG-CZ 3.76Å; L119-F182 HydrophobicContact CD1-CZ 4.09Å; M180-F182 HydrophobicContact CB-CD2 4.28Å; M180-F182 HydrophobicContact CB-CE1 4.33Å; M180-F182 HydrophobicContact CB-CE2 3.47Å; M180-F182 VanDerWaalsContact CB-CE2 3.47Å; M180-F182 HydrophobicContact CB-CZ 3.49Å; M180-F182 VanDerWaalsContact CB-CZ 3.49Å; M180-F182 HydrophobicContact CG-CZ 4.22Å; M180-F182 HydrophobicContact SD-CE1 4.24Å; M180-F182 HydrophobicContact SD-CZ 3.7Å; F182-G186 WeakPolarHBondContact CD1-O 3.31Å; F182-V187 CarbonylContact C-O 3.52Å; F182-V187 VanDerWaalsContact CA-O 3.26Å; F182-V187 WeakPolarHBondContact CA-O 3.45Å; F182-L188 HydrophobicContact CD1-CB 4.35Å; F182-L188 HydrophobicContact CE1-CB 4.19Å; F182-K189 WeakPolarHBondContact O-CE 3.32Å; F182-K189 PolarHBondContact O-NZ 2.66Å
183D98.1Very high97.9Very high58 Ų5851.5 Ų51.531%0.3128%0.284SS..  trans-76-179.1170.870.220.5000112.3T185 G186 V187 K189D183-T185 PolarHBondContact O-N 3.09Å; D183-T185 VanDerWaalsContact O-N 3.16Å; D183-T185 WeakPolarHBondContact OD1-CA 3.36Å; D183-T185 WeakPolarHBondContact OD1-CB 3.42Å; D183-T185 PolarHBondContact OD1-N 2.99Å; D183-T185 PolarHBondContact OD1-OG1 3.32Å; D183-T185 PolarHBondContact OD2-OG1 3.11Å; D183-G186 PolarHBondContact O-N 3.46Å; D183-G186 PolarHBondContact OD1-N 2.89Å; D183-V187 PolarHBondContact N-O 3.45Å; D183-V187 PolarHBondContact OD1-N 2.88Å; D183-K189 HydrophobicContact CB-CD 4.02Å
184E97.3Very high97.7Very high207 Ų20756.9 Ų56.997%0.96731%0.308SS*.THydrogen-bonded Turntrans-61.1-21.8-179.6-61.2178.9-174.100113.2
185T96.9Very high97.6Very high114 Ų11454.3 Ų54.370%0.69930%0.298SS*.THydrogen-bonded Turntrans-92-2.3177.573.10000112.8D183D183-T185 PolarHBondContact O-N 3.09Å; D183-T185 VanDerWaalsContact O-N 3.16Å; D183-T185 WeakPolarHBondContact OD1-CA 3.36Å; D183-T185 WeakPolarHBondContact OD1-CB 3.42Å; D183-T185 PolarHBondContact OD1-N 2.99Å; D183-T185 PolarHBondContact OD1-OG1 3.32Å; D183-T185 PolarHBondContact OD2-OG1 3.11Å
186G97.8Very high97.5Very high22 Ų2254.7 Ų54.723%0.22730%0.3CS..SBendtrans81.621.4-179.100000113.9P115 K116 F182 D183P115-G186 CarbonylContact C-O 3.57Å; P115-G186 WeakPolarHBondContact CA-O 3.43Å; K116-G186 PolarHBondContact N-O 3.41Å; F182-G186 WeakPolarHBondContact CD1-O 3.31Å; D183-G186 PolarHBondContact O-N 3.46Å; D183-G186 PolarHBondContact OD1-N 2.89Å
187V98.4Very high97.4Very high36 Ų3653.9 Ų53.922%0.21830%0.295CS..BIsolated β-bridgetrans-98.4138.6177.8173.60000110.6A113 F182 D183 K189A113-V187 HydrophobicContact CB-CG1 3.75Å; F182-V187 CarbonylContact C-O 3.52Å; F182-V187 VanDerWaalsContact CA-O 3.26Å; F182-V187 WeakPolarHBondContact CA-O 3.45Å; D183-V187 PolarHBondContact N-O 3.45Å; D183-V187 PolarHBondContact OD1-N 2.88Å; V187-K189 PolarHBondContact O-N 3.16Å
188L98.6Very high97.1Very high5 Ų554 Ų543%0.02630%0.295CS..EExtended strand (participates in β ladder)trans-58.8120.5179.5177.566.5000110.6L109 V110 L114 M180 F182 G190 F191L109-L188 HydrophobicContact CB-CD2 4.1Å; V110-L188 HydrophobicContact CG2-CD2 4.2Å; V110-L188 HydrophobicContact CG2-CG 4.02Å; L114-L188 HydrophobicContact CB-CB 4.06Å; L114-L188 HydrophobicContact CB-CD2 4.28Å; L114-L188 HydrophobicContact CD1-CD2 3.94Å; L114-L188 HydrophobicContact CG-CD2 4.45Å; L114-L188 WeakPolarHBondContact O-CB 3.45Å; L114-L188 PolarHBondContact O-N 3.25Å; M180-L188 HydrophobicContact CB-CD1 3.63Å; M180-L188 HydrophobicContact CE-CD2 4.16Å; M180-L188 HydrophobicContact CG-CD1 3.64Å; M180-L188 HydrophobicContact SD-CD1 3.9Å; M180-L188 HydrophobicContact SD-CD2 4.34Å; F182-L188 HydrophobicContact CD1-CB 4.35Å; F182-L188 HydrophobicContact CE1-CB 4.19Å; L188-G190 WeakPolarHBondContact CD1-O 3.36Å; L188-F191 HydrophobicContact CD1-CE2 4.47Å
189K98.3Very high96.7Very high114 Ų11455.3 Ų55.350%0.49630%0.301SS..EExtended strand (participates in β ladder)trans-116.2-14.9176.668.2175.9-175.7-167.40113.7D181 F182 D183 V187D181-K189 HydrophobicContact CB-CG 4.44Å; D181-K189 WeakPolarHBondContact O-CG 3.42Å; D181-K189 PolarHBondContact O-N 3.1Å; D181-K189 WeakPolarHBondContact OD2-CE 3.47Å; D181-K189 IonicContact OD2-NZ 3.47Å; D181-K189 PolarHBondContact OD2-NZ 3.24Å; F182-K189 WeakPolarHBondContact O-CE 3.32Å; F182-K189 PolarHBondContact O-NZ 2.66Å; D183-K189 HydrophobicContact CB-CD 4.02Å; V187-K189 PolarHBondContact O-N 3.16Å
190G98.1Very high96.5Very high18 Ų1853.5 Ų53.519%0.18629%0.294CS..EExtended strand (participates in β ladder)trans174.8-161.2-178.100000112.7D181 L188D181-G190 PolarHBondContact N-O 3.33Å; D181-G190 PolarHBondContact O-N 2.98Å; L188-G190 WeakPolarHBondContact CD1-O 3.36Å
191F98.3Very high96.1Very high45 Ų4553.7 Ų53.720%0.19729%0.294CS..EExtended strand (participates in β ladder)trans-128.3146.6175.6-74.1-100.5000109.4H106 I155 N178 F179 M180 L188H106-F191 HydrophobicContact CB-CD2 3.75Å; H106-F191 HydrophobicContact CB-CE2 3.51Å; H106-F191 HydrophobicContact CB-CZ 4.35Å; H106-F191 AromaticContact CD2-CE2 3.57Å; H106-F191 AromaticContact CD2-CZ 3.5Å; H106-F191 AromaticContact CG-CD2 3.66Å; H106-F191 AromaticContact CG-CE2 3.42Å; H106-F191 VanDerWaalsContact CG-CE2 3.42Å; H106-F191 AromaticContact CG-CZ 3.84Å; H106-F191 AromaticContact ND1-CD2 3.69Å; H106-F191 AromaticContact ND1-CE2 3.89Å; H106-F191 AromaticContact ND1-CG 3.91Å; H106-F191 AromaticContact NE2-CE1 3.79Å; H106-F191 AromaticContact NE2-CZ 3.71Å; I155-F191 HydrophobicContact CG1-CE1 4.25Å; I155-F191 HydrophobicContact CG2-CE1 4.25Å; N178-F191 HydrophobicContact CB-CD1 3.91Å; N178-F191 HydrophobicContact CB-CE1 4.39Å; F179-F191 CarbonylContact O-C 3.52Å; F179-F191 WeakPolarHBondContact O-CA 3.43Å; M180-F191 HydrophobicContact CE-CZ 4.26Å; M180-F191 HydrophobicContact CG-CD1 4.33Å; M180-F191 HydrophobicContact CG-CE1 3.75Å; M180-F191 HydrophobicContact CG-CZ 4.01Å; L188-F191 HydrophobicContact CD1-CE2 4.47Å
192K96.7Very high95.8Very high114 Ų11453.9 Ų53.950%0.49629%0.294SS..  trans-85.5148.5-174.1-62.9179.7-179.6170.40111.4F179 M180 D181F179-K192 HydrophobicContact CB-CD 4.44Å; F179-K192 PolarHBondContact O-N 3.05Å; M180-K192 VanDerWaalsContact O-CE 3.27Å; M180-K192 WeakPolarHBondContact O-CE 3.38Å; D181-K192 HydrophobicContact CB-CG 3.75Å; D181-K192 VanDerWaalsContact OD1-CE 3.29Å; D181-K192 WeakPolarHBondContact OD1-CE 3.39Å
193G94Very high95.1Very high79 Ų7955.2 Ų55.281%0.81430%0.302SS*.SBendtrans66.2-151.8173.500000112.1
194E94.1Very high94.3Very high124 Ų12452.9 Ų52.958%0.57929%0.291SS*.SBendtrans-95.9142.7178.8-67.3-166.4-142.100111.2I196 R207E194-I196 PolarHBondContact O-N 2.9Å; E194-R207 IonicContact OE1-CZ 3.81Å; E194-R207 IonicContact OE1-NH1 2.8Å; E194-R207 PolarHBondContact OE1-NH1 3.09Å; E194-R207 IonicContact OE1-NH2 2.65Å; E194-R207 PolarHBondContact OE1-NH2 3.43Å; E194-R207 VanDerWaalsContact OE1-NH2 3.13Å; E194-R207 IonicContact OE2-CZ 2.77Å; E194-R207 IonicContact OE2-NH1 3.2Å; E194-R207 PolarHBondContact OE2-NH1 2.83Å; E194-R207 IonicContact OE2-NH2 2.62Å; E194-R207 PolarHBondContact OE2-NH2 2.92Å
195L96.3Very high93.5Very high43 Ų4343 Ų4323%0.22525%0.245CC..PPolyproline II helixtrans-57.6130.2179.7173.366.1000110.9V99 Y102 N200V99-L195 HydrophobicContact CG1-CD2 4.41Å; Y102-L195 HydrophobicContact CD1-CD1 3.75Å; Y102-L195 HydrophobicContact CG-CD1 3.98Å; Y102-L195 HydrophobicContact CG-CD2 4.45Å; L195-N200 PolarHBondContact O-ND2 3.15Å
196I96.8Very high92.7Very high15 Ų1541.3 Ų41.38%0.07723%0.231CC..PPolyproline II helixtrans-102.6121.5166-60.1156.1000107.6F151 A153 V176 N178 E194 N200 K201F151-I196 HydrophobicContact CD2-CG2 4.38Å; F151-I196 HydrophobicContact CE2-CD1 3.83Å; F151-I196 HydrophobicContact CE2-CG1 4.11Å; F151-I196 HydrophobicContact CE2-CG2 3.68Å; F151-I196 HydrophobicContact CZ-CG2 4.45Å; A153-I196 HydrophobicContact CB-CG2 4.15Å; V176-I196 HydrophobicContact CG1-CD1 3.93Å; N178-I196 PolarHBondContact ND2-O 3.32Å; N178-I196 PolarHBondContact OD1-N 3.41Å; N178-I196 PolarHBondContact OD1-O 2.96Å; E194-I196 PolarHBondContact O-N 2.9Å; I196-N200 WeakPolarHBondContact CA-OD1 3.42Å; I196-K201 HydrophobicContact CG2-CG 4.33Å
197H94.9Very high92.1Very high1 Ų146.3 Ų46.31%0.00524%0.243CC..  trans-126.1173.7170.964.984.1000110.1Y95 M98 Y102 F199 N200Y95-H197 AromaticContact CD1-NE2 3.98Å; Y95-H197 AromaticContact CD2-CE1 3.63Å; Y95-H197 AromaticContact CE1-NE2 3.53Å; Y95-H197 AromaticContact CE2-CE1 3.58Å; Y95-H197 AromaticContact CE2-NE2 3.63Å; Y95-H197 AromaticContact CG-CE1 3.93Å; Y95-H197 AromaticContact CZ-CE1 3.8Å; Y95-H197 AromaticContact CZ-NE2 3.35Å; Y95-H197 VanDerWaalsContact CZ-NE2 3.35Å; M98-H197 HydrophobicContact CB-CB 4.19Å; Y102-H197 HydrophobicContact CD2-CB 3.94Å; Y102-H197 HydrophobicContact CE2-CB 3.81Å; Y102-H197 HydrophobicContact CG-CB 4.41Å; H197-F199 PolarHBondContact ND1-N 2.96Å; H197-F199 PolarHBondContact O-N 2.99Å; H197-N200 VanDerWaalsContact CD2-CG 3.45Å; H197-N200 PolarHBondContact CD2-ND2 3.22Å; H197-N200 VanDerWaalsContact CD2-ND2 3.33Å; H197-N200 PolarHBondContact N-OD1 2.89Å; H197-N200 PolarHBondContact NE2-ND2 3.33Å; H197-N200 PolarHBondContact O-N 2.86Å; H197-N200 PolarHBondContact O-OD1 3.4Å
198V91.3Very high91.4Very high12 Ų1246.3 Ų46.37%0.07324%0.242CC..THydrogen-bonded Turntrans-53.5-26-173.164.60000114.9E84 M98 G229E84-V198 HydrophobicContact CG-CG1 4.12Å; M98-V198 HydrophobicContact CG-CG1 3.97Å; M98-V198 HydrophobicContact SD-CG1 3.92Å; V198-G229 WeakPolarHBondContact O-CA 3.41Å
199F91.4Very high90.5Very high31 Ų3149 Ų4914%0.13626%0.259CS..THydrogen-bonded Turntrans-108.7-0.2-174-59.3-49000115.6E84 V91 K94 Y95 M98 H197E84-F199 HydrophobicContact CG-CE2 4.32Å; E84-F199 HydrophobicContact CG-CZ 4.07Å; V91-F199 HydrophobicContact CG1-CB 3.79Å; V91-F199 HydrophobicContact CG1-CD1 3.84Å; V91-F199 HydrophobicContact CG1-CG 3.83Å; V91-F199 HydrophobicContact CG2-CD1 4.42Å; K94-F199 HydrophobicContact CB-CD2 3.95Å; K94-F199 HydrophobicContact CB-CE2 3.55Å; K94-F199 HydrophobicContact CB-CZ 4.36Å; K94-F199 HydrophobicContact CD-CE2 3.81Å; K94-F199 HydrophobicContact CD-CZ 3.81Å; K94-F199 HydrophobicContact CG-CE2 4.33Å; Y95-F199 HydrophobicContact CD2-CB 4.37Å; M98-F199 HydrophobicContact CG-CD2 3.52Å; M98-F199 HydrophobicContact CG-CE2 3.62Å; M98-F199 HydrophobicContact SD-CE2 4.2Å; H197-F199 PolarHBondContact ND1-N 2.96Å; H197-F199 PolarHBondContact O-N 2.99Å
200N92.9Very high89.8Confident11 Ų1150.5 Ų50.56%0.05927%0.268CS..  trans-117.817-178.478.8-12.8000114.1Y95 L195 I196 H197 H202 D203 G204Y95-N200 HydrophobicContact CE2-CB 3.61Å; Y95-N200 WeakPolarHBondContact OH-CB 3.18Å; L195-N200 PolarHBondContact O-ND2 3.15Å; I196-N200 WeakPolarHBondContact CA-OD1 3.42Å; H197-N200 VanDerWaalsContact CD2-CG 3.45Å; H197-N200 PolarHBondContact CD2-ND2 3.22Å; H197-N200 VanDerWaalsContact CD2-ND2 3.33Å; H197-N200 PolarHBondContact N-OD1 2.89Å; H197-N200 PolarHBondContact NE2-ND2 3.33Å; H197-N200 PolarHBondContact O-N 2.86Å; H197-N200 PolarHBondContact O-OD1 3.4Å; N200-H202 PolarHBondContact O-N 3.25Å; N200-H202 VanDerWaalsContact O-N 3.13Å; N200-D203 WeakPolarHBondContact O-CB 3.16Å; N200-D203 PolarHBondContact O-N 2.8Å; N200-G204 PolarHBondContact O-N 3.47Å
201K91.9Very high89.4Confident3 Ų351.5 Ų51.51%0.01327%0.266CS..Hα-helixtrans-59.1-25.9176.6-65.7-163.2-178.9-175.50112.9D37 F151 I196 D203 G204 A205 D230 M233D37-K201 VanDerWaalsContact CG-NZ 3.31Å; D37-K201 IonicContact OD1-NZ 2.69Å; D37-K201 PolarHBondContact OD1-NZ 3.35Å; F151-K201 HydrophobicContact CD1-CB 4.4Å; F151-K201 HydrophobicContact CE1-CB 3.83Å; F151-K201 HydrophobicContact CE1-CG 4.38Å; F151-K201 WeakPolarHBondContact CE1-O 3.48Å; F151-K201 HydrophobicContact CE2-CG 4.38Å; F151-K201 HydrophobicContact CZ-CB 3.91Å; F151-K201 HydrophobicContact CZ-CG 4.17Å; F151-K201 VanDerWaalsContact CZ-O 3.29Å; F151-K201 WeakPolarHBondContact CZ-O 3.25Å; F151-K201 WeakPolarHBondContact O-CE 3.42Å; F151-K201 PolarHBondContact O-NZ 3.13Å; I196-K201 HydrophobicContact CG2-CG 4.33Å; K201-D203 VanDerWaalsContact C-N 3.34Å; K201-D203 PolarHBondContact O-N 3.49Å; K201-G204 PolarHBondContact O-N 3.41Å; K201-A205 WeakPolarHBondContact O-CB 3.44Å; K201-A205 PolarHBondContact O-N 2.97Å; K201-D230 VanDerWaalsContact CE-OD1 3.29Å; K201-D230 WeakPolarHBondContact CE-OD1 3.4Å; K201-D230 IonicContact NZ-OD1 3.44Å; K201-D230 PolarHBondContact NZ-OD1 3.2Å; K201-M233 HydrophobicContact CB-CG 4.06Å; K201-M233 HydrophobicContact CD-CG 3.51Å; K201-M233 HydrophobicContact CD-SD 3.67Å; K201-M233 HydrophobicContact CG-CG 4.43Å; K201-M233 PolarHBondContact NZ-SD 2.93Å; K201-M233 VanDerWaalsContact NZ-SD 3.45Å
202H90.5Very high89Confident56 Ų5649.4 Ų49.426%0.25926%0.257SS..Hα-helixtrans-51.1-51168.4174.862.5000112.5N200 G204 A205 L206 R232 D235N200-H202 PolarHBondContact O-N 3.25Å; N200-H202 VanDerWaalsContact O-N 3.13Å; H202-G204 PolarHBondContact O-N 3.41Å; H202-A205 WeakPolarHBondContact O-CB 3.38Å; H202-A205 PolarHBondContact O-N 3.12Å; H202-L206 VanDerWaalsContact CE1-CD1 3.45Å; H202-L206 WeakPolarHBondContact CE1-CD1 3.49Å; H202-L206 WeakPolarHBondContact NE2-CD1 3.19Å; H202-L206 WeakPolarHBondContact O-CG 3.46Å; H202-L206 PolarHBondContact O-N 3.32Å; H202-L206 VanDerWaalsContact O-N 3.12Å; H202-R232 HydrophobicContact CB-CB 4.06Å; H202-R232 PolarHBondContact ND1-NH2 3.34Å; H202-R232 VanDerWaalsContact ND1-NH2 3.11Å; H202-D235 IonicContact CE1-OD2 2.69Å; H202-D235 IonicContact CG-OD2 2.83Å; H202-D235 WeakPolarHBondContact ND1-CB 3.29Å; H202-D235 IonicContact ND1-OD2 2.75Å; H202-D235 PolarHBondContact ND1-OD2 3.38Å
203D84.1Confident88.6Confident52 Ų5248.5 Ų48.528%0.27826%0.257SS..Hα-helixtrans-65.1-43.3-175.5-58-31.3000111N200 K201 L206 R207N200-D203 WeakPolarHBondContact O-CB 3.16Å; N200-D203 PolarHBondContact O-N 2.8Å; K201-D203 VanDerWaalsContact C-N 3.34Å; K201-D203 PolarHBondContact O-N 3.49Å; D203-L206 PolarHBondContact O-N 3.49Å; D203-R207 WeakPolarHBondContact O-CG 3.41Å; D203-R207 PolarHBondContact O-N 3.46Å; D203-R207 VanDerWaalsContact O-N 3.14Å
204G81.1Confident88.5Confident8 Ų851.1 Ų51.18%0.08225%0.249CC..Hα-helixtrans-67.9-33.9176.600000112.8N200 K201 H202 L206 R207 N208N200-G204 PolarHBondContact O-N 3.47Å; K201-G204 PolarHBondContact O-N 3.41Å; H202-G204 PolarHBondContact O-N 3.41Å; G204-L206 PolarHBondContact O-N 2.91Å; G204-R207 PolarHBondContact O-N 3.22Å; G204-N208 PolarHBondContact O-N 2.89Å; G204-N208 PolarHBondContact O-ND2 3Å
205A80.4Confident88.4Confident0 Ų046.4 Ų46.40%023%0.227CC..Hα-helixtrans-61.2-45.8174.200000110.8F151 K201 H202 R207 N208 F212 D235F151-A205 HydrophobicContact CE1-CB 4.07Å; K201-A205 WeakPolarHBondContact O-CB 3.44Å; K201-A205 PolarHBondContact O-N 2.97Å; H202-A205 WeakPolarHBondContact O-CB 3.38Å; H202-A205 PolarHBondContact O-N 3.12Å; A205-R207 VanDerWaalsContact C-N 3.28Å; A205-R207 PolarHBondContact O-N 3.48Å; A205-N208 PolarHBondContact O-N 3.35Å; A205-F212 WeakPolarHBondContact O-CE2 3.32Å; A205-D235 HydrophobicContact CB-CB 4.37Å
206L79.8Confident88.2Confident78 Ų7850.4 Ų50.441%0.40824%0.243SC..Hα-helixtrans-67-25.4178.4-66.3-180000113.8H202 D203 G204 N208 T209H202-L206 VanDerWaalsContact CE1-CD1 3.45Å; H202-L206 WeakPolarHBondContact CE1-CD1 3.49Å; H202-L206 WeakPolarHBondContact NE2-CD1 3.19Å; H202-L206 WeakPolarHBondContact O-CG 3.46Å; H202-L206 PolarHBondContact O-N 3.32Å; H202-L206 VanDerWaalsContact O-N 3.12Å; D203-L206 PolarHBondContact O-N 3.49Å; G204-L206 PolarHBondContact O-N 2.91Å; L206-N208 VanDerWaalsContact C-N 3.32Å; L206-T209 WeakPolarHBondContact O-CG2 3.42Å; L206-T209 PolarHBondContact O-OG1 2.8Å
207R86.6Confident88.1Confident128 Ų12855 Ų5548%0.48327%0.267SS..Hα-helixtrans-76.8-19.3175.3-72.6168.7-171.8172.8-1.9113.8E194 D203 G204 A205 T209E194-R207 IonicContact OE1-CZ 3.81Å; E194-R207 IonicContact OE1-NH1 2.8Å; E194-R207 PolarHBondContact OE1-NH1 3.09Å; E194-R207 IonicContact OE1-NH2 2.65Å; E194-R207 PolarHBondContact OE1-NH2 3.43Å; E194-R207 VanDerWaalsContact OE1-NH2 3.13Å; E194-R207 IonicContact OE2-CZ 2.77Å; E194-R207 IonicContact OE2-NH1 3.2Å; E194-R207 PolarHBondContact OE2-NH1 2.83Å; E194-R207 IonicContact OE2-NH2 2.62Å; E194-R207 PolarHBondContact OE2-NH2 2.92Å; D203-R207 WeakPolarHBondContact O-CG 3.41Å; D203-R207 PolarHBondContact O-N 3.46Å; D203-R207 VanDerWaalsContact O-N 3.14Å; G204-R207 PolarHBondContact O-N 3.22Å; A205-R207 VanDerWaalsContact C-N 3.28Å; A205-R207 PolarHBondContact O-N 3.48Å; R207-T209 VanDerWaalsContact C-N 3.28Å; R207-T209 PolarHBondContact O-N 3.09Å
208N84.4Confident88.2Confident35 Ų3556 Ų5619%0.18727%0.273CS..THydrogen-bonded Turntrans-95.626.1177.7-71.8-81.5000112F149 G204 A205 L206 E210 Y211 F212F149-N208 HydrophobicContact CE2-CB 4.38Å; F149-N208 HydrophobicContact CZ-CB 4.13Å; G204-N208 PolarHBondContact O-N 2.89Å; G204-N208 PolarHBondContact O-ND2 3Å; A205-N208 PolarHBondContact O-N 3.35Å; L206-N208 VanDerWaalsContact C-N 3.32Å; N208-E210 PolarHBondContact O-N 3.41Å; N208-Y211 WeakPolarHBondContact O-CB 3.42Å; N208-Y211 PolarHBondContact O-N 2.91Å; N208-F212 HydrophobicContact CB-CD2 4.27Å; N208-F212 HydrophobicContact CB-CE2 3.99Å; N208-F212 WeakPolarHBondContact O-CD2 3.47Å; N208-F212 PolarHBondContact O-N 3.34Å; N208-F212 VanDerWaalsContact O-N 3.09Å
209T78.3Confident88.5Confident62 Ų6255.6 Ų55.638%0.3827%0.27SS..Hα-helixtrans-56.9-33.3178.438.70000113L206 R207 Y211 F212 N213L206-T209 WeakPolarHBondContact O-CG2 3.42Å; L206-T209 PolarHBondContact O-OG1 2.8Å; R207-T209 VanDerWaalsContact C-N 3.28Å; R207-T209 PolarHBondContact O-N 3.09Å; T209-Y211 PolarHBondContact O-N 2.77Å; T209-F212 PolarHBondContact O-N 3.08Å; T209-N213 WeakPolarHBondContact O-CB 3.36Å; T209-N213 PolarHBondContact O-N 3.26Å; T209-N213 PolarHBondContact O-ND2 2.86Å; T209-N213 VanDerWaalsContact O-ND2 3.07Å
210E84.3Confident88.9Confident146 Ų14654.1 Ų54.168%0.68226%0.264SS*.Hα-helixtrans-61-44.2174.7-170.8179.8177.400111.9N208 N213 Q214N208-E210 PolarHBondContact O-N 3.41Å; E210-N213 PolarHBondContact O-N 3.44Å; E210-Q214 WeakPolarHBondContact O-CG 3.29Å; E210-Q214 PolarHBondContact O-N 3.15Å
211Y90.4Very high89.1Confident38 Ų3853.6 Ų53.615%0.14926%0.261CS..Hα-helixtrans-62.3-49.5175.4174.9-96.1000111.1F149 K174 N208 T209 N213 Q214 L215F149-Y211 HydrophobicContact CB-CE1 3.92Å; F149-Y211 AromaticContact CD2-CD1 3.69Å; F149-Y211 HydrophobicContact CD2-CD1 3.69Å; F149-Y211 AromaticContact CD2-CE1 3.35Å; F149-Y211 HydrophobicContact CD2-CE1 3.35Å; F149-Y211 HydrophobicContact CD2-CE2 4.49Å; F149-Y211 HydrophobicContact CD2-CG 4.39Å; F149-Y211 AromaticContact CD2-CZ 3.8Å; F149-Y211 AromaticContact CE2-CD1 3.96Å; F149-Y211 HydrophobicContact CE2-CD1 3.96Å; F149-Y211 HydrophobicContact CE2-CE1 4.11Å; F149-Y211 HydrophobicContact CE2-CG 4.45Å; F149-Y211 HydrophobicContact CG-CD1 4.49Å; F149-Y211 AromaticContact CG-CE1 3.91Å; F149-Y211 HydrophobicContact CG-CE1 3.91Å; K174-Y211 HydrophobicContact CB-CE2 3.89Å; K174-Y211 HydrophobicContact CG-CD2 4.26Å; K174-Y211 HydrophobicContact CG-CE2 3.98Å; N208-Y211 WeakPolarHBondContact O-CB 3.42Å; N208-Y211 PolarHBondContact O-N 2.91Å; T209-Y211 PolarHBondContact O-N 2.77Å; Y211-N213 VanDerWaalsContact C-N 3.31Å; Y211-N213 PolarHBondContact O-N 3.34Å; Y211-Q214 WeakPolarHBondContact O-CB 3.45Å; Y211-Q214 PolarHBondContact O-N 3.27Å; Y211-L215 HydrophobicContact CD1-CD1 4.19Å; Y211-L215 HydrophobicContact CE1-CD1 3.49Å; Y211-L215 VanDerWaalsContact CE1-CD1 3.49Å; Y211-L215 HydrophobicContact CE2-CD1 4.13Å; Y211-L215 VanDerWaalsContact CZ-CD1 3.46Å; Y211-L215 PolarHBondContact O-N 3.17Å
212F88.9Confident89.5Confident1 Ų153.6 Ų53.60%0.00426%0.261CS..Hα-helixtrans-67.8-30-179.3-66.9-60.9000113.4I35 F149 A205 N208 T209 Q214 L215 K216 G236 V237I35-F212 HydrophobicContact CD1-CE1 3.83Å; I35-F212 HydrophobicContact CD1-CZ 4.29Å; I35-F212 HydrophobicContact CG1-CE1 4.49Å; F149-F212 HydrophobicContact CD1-CZ 4.09Å; F149-F212 AromaticContact CE1-CZ 3.99Å; F149-F212 HydrophobicContact CE1-CZ 3.99Å; F149-F212 HydrophobicContact CG-CZ 4.42Å; F149-F212 HydrophobicContact CZ-CZ 4.25Å; A205-F212 WeakPolarHBondContact O-CE2 3.32Å; N208-F212 HydrophobicContact CB-CD2 4.27Å; N208-F212 HydrophobicContact CB-CE2 3.99Å; N208-F212 WeakPolarHBondContact O-CD2 3.47Å; N208-F212 PolarHBondContact O-N 3.34Å; N208-F212 VanDerWaalsContact O-N 3.09Å; T209-F212 PolarHBondContact O-N 3.08Å; F212-Q214 VanDerWaalsContact C-N 3.33Å; F212-L215 CarbonylContact O-C 3.6Å; F212-L215 VanDerWaalsContact O-C 3.28Å; F212-L215 PolarHBondContact O-N 2.87Å; F212-L215 VanDerWaalsContact O-N 3.11Å; F212-K216 PolarHBondContact O-N 2.98Å; F212-G236 WeakPolarHBondContact CB-O 3.39Å; F212-G236 WeakPolarHBondContact CD2-O 3.2Å; F212-G236 WeakPolarHBondContact CG-O 3.5Å; F212-V237 HydrophobicContact CD1-CG2 3.85Å; F212-V237 HydrophobicContact CE1-CG2 3.88Å
213N88.4Confident89.9Confident95 Ų9550.9 Ų50.951%0.50825%0.249SC..Hα-helixtrans-68.4-33.2174.8-75.8-26.4000112.2T209 E210 Y211 L215 K216T209-N213 WeakPolarHBondContact O-CB 3.36Å; T209-N213 PolarHBondContact O-N 3.26Å; T209-N213 PolarHBondContact O-ND2 2.86Å; T209-N213 VanDerWaalsContact O-ND2 3.07Å; E210-N213 PolarHBondContact O-N 3.44Å; Y211-N213 VanDerWaalsContact C-N 3.31Å; Y211-N213 PolarHBondContact O-N 3.34Å; N213-L215 PolarHBondContact O-N 3.03Å; N213-K216 PolarHBondContact O-N 2.99Å
214Q90.9Very high90.6Very high135 Ų13548.4 Ų48.463%0.63124%0.235SC*.Hα-helixtrans-66.9-25.6171.8-67.3170.71500111.7E210 Y211 F212E210-Q214 WeakPolarHBondContact O-CG 3.29Å; E210-Q214 PolarHBondContact O-N 3.15Å; Y211-Q214 WeakPolarHBondContact O-CB 3.45Å; Y211-Q214 PolarHBondContact O-N 3.27Å; F212-Q214 VanDerWaalsContact C-N 3.33Å
215L92.6Very high91.4Very high24 Ų2448 Ų4813%0.12623%0.232CC..THydrogen-bonded Turntrans-104.623.8-180-57.5-175.8000113.5P147 Y211 F212 N213 D217 N218P147-L215 HydrophobicContact CB-CD1 3.54Å; P147-L215 HydrophobicContact CB-CD2 4.15Å; P147-L215 HydrophobicContact CG-CD1 3.9Å; P147-L215 HydrophobicContact CG-CD2 3.64Å; P147-L215 HydrophobicContact CG-CG 4.41Å; Y211-L215 HydrophobicContact CD1-CD1 4.19Å; Y211-L215 HydrophobicContact CE1-CD1 3.49Å; Y211-L215 VanDerWaalsContact CE1-CD1 3.49Å; Y211-L215 HydrophobicContact CE2-CD1 4.13Å; Y211-L215 VanDerWaalsContact CZ-CD1 3.46Å; Y211-L215 PolarHBondContact O-N 3.17Å; F212-L215 CarbonylContact O-C 3.6Å; F212-L215 VanDerWaalsContact O-C 3.28Å; F212-L215 PolarHBondContact O-N 2.87Å; F212-L215 VanDerWaalsContact O-N 3.11Å; N213-L215 PolarHBondContact O-N 3.03Å; L215-D217 PolarHBondContact O-N 2.98Å; L215-D217 VanDerWaalsContact O-N 3.08Å; L215-N218 HydrophobicContact CB-CB 4.26Å; L215-N218 WeakPolarHBondContact O-CA 3.47Å; L215-N218 WeakPolarHBondContact O-CB 3.41Å; L215-N218 PolarHBondContact O-N 3.34Å
216K92.3Very high92.3Very high127 Ų12749.6 Ų49.655%0.55224%0.24SC*.THydrogen-bonded Turntrans-56.9-27.2-177.468.5-179.6-174.6176.90114.1F212 N213F212-K216 PolarHBondContact O-N 2.98Å; N213-K216 PolarHBondContact O-N 2.99Å
217D94.8Very high93Very high112 Ų11246.6 Ų46.660%0.59923%0.225SC*.THydrogen-bonded Turntrans-83.6-18-179.7-61.2-32.5000111.3L215 S219L215-D217 PolarHBondContact O-N 2.98Å; L215-D217 VanDerWaalsContact O-N 3.08Å; D217-S219 PolarHBondContact O-N 2.93Å
218N97.1Very high93.3Very high23 Ų2342.4 Ų42.412%0.12321%0.211CC..  trans-79.760.5174.1-57.783.8000110.9K31 L32 Q33 L215 N220K31-N218 CarbonylContact O-C 3.28Å; K31-N218 WeakPolarHBondContact O-CA 3.49Å; L32-N218 PolarHBondContact O-ND2 3.18Å; Q33-N218 HydrophobicContact CB-CB 3.95Å; Q33-N218 HydrophobicContact CG-CB 4.03Å; Q33-N218 PolarHBondContact NE2-O 3.26Å; L215-N218 HydrophobicContact CB-CB 4.26Å; L215-N218 WeakPolarHBondContact O-CA 3.47Å; L215-N218 WeakPolarHBondContact O-CB 3.41Å; L215-N218 PolarHBondContact O-N 3.34Å; N218-N220 PolarHBondContact O-N 3.09Å
219S97.9Very high93.7Very high2 Ų241.1 Ų41.11%0.01421%0.206CC..  trans-76.1-1.3-174.257.10000115.2K31 D217 I221 N239 E241 H242K31-S219 PolarHBondContact O-N 2.93Å; D217-S219 PolarHBondContact O-N 2.93Å; S219-I221 WeakPolarHBondContact O-CD1 3.41Å; S219-N239 WeakPolarHBondContact CA-O 3.34Å; S219-E241 PolarHBondContact O-N 3.24Å; S219-E241 PolarHBondContact OG-OE1 3.5Å; S219-H242 PolarHBondContact O-N 2.78Å
220N98.7Very high94.6Very high1 Ų138.2 Ų38.21%0.00519%0.188CC..EExtended strand (participates in β ladder)trans-106.7124.1176.8-74.7-7.2000110.5G23 L24 K31 L32 Q33 N218 H242G23-N220 PolarHBondContact O-ND2 3.34Å; L24-N220 HydrophobicContact CD2-CB 3.67Å; K31-N220 HydrophobicContact CB-CB 4.11Å; K31-N220 WeakPolarHBondContact O-CA 3.49Å; K31-N220 WeakPolarHBondContact O-CB 3.39Å; K31-N220 PolarHBondContact O-N 2.86Å; L32-N220 CarbonylContact C-O 3.53Å; L32-N220 VanDerWaalsContact CA-O 3.32Å; L32-N220 WeakPolarHBondContact CA-O 3.29Å; Q33-N220 PolarHBondContact N-O 3.37Å; N218-N220 PolarHBondContact O-N 3.09Å; N220-H242 CarbonylContact C-O 3.53Å; N220-H242 VanDerWaalsContact CA-O 3.3Å; N220-H242 WeakPolarHBondContact CA-O 3.06Å; N220-H242 PolarHBondContact OD1-CD2 3.06Å
221I98.8Very high95.2Very high0 Ų032.3 Ų32.30%016%0.161CC..EExtended strand (participates in β ladder)trans-124133.7-171.2-55.496.3000110.7Q33 I35 S219 V237 V240 H242 I243 L244Q33-I221 HydrophobicContact CG-CG1 3.82Å; Q33-I221 WeakPolarHBondContact O-CA 3.06Å; I35-I221 HydrophobicContact CB-CG2 4.37Å; I35-I221 HydrophobicContact CD1-CG2 3.98Å; I35-I221 HydrophobicContact CG1-CG2 4.1Å; S219-I221 WeakPolarHBondContact O-CD1 3.41Å; I221-V237 HydrophobicContact CD1-CG1 4.06Å; I221-V237 HydrophobicContact CG1-CG1 4.45Å; I221-V240 HydrophobicContact CD1-CB 4.15Å; I221-V240 HydrophobicContact CD1-CG1 3.76Å; I221-V240 HydrophobicContact CD1-CG2 3.8Å; I221-H242 PolarHBondContact N-O 2.63Å; I221-I243 HydrophobicContact CB-CB 4.32Å; I221-I243 HydrophobicContact CB-CD1 4.34Å; I221-I243 HydrophobicContact CB-CG1 4.05Å; I221-I243 HydrophobicContact CG2-CD1 4.25Å; I221-I243 HydrophobicContact CG2-CG1 4.27Å; I221-I243 WeakPolarHBondContact O-CA 3.33Å; I221-L244 PolarHBondContact O-N 2.59Å
222I98.9Very high95.4Very high2 Ų235.9 Ų35.91%0.0117%0.174CC..EExtended strand (participates in β ladder)trans-105.2119.6158.4-63.4172.4000107.3L24 L32 Q33 I34 I35 L224 I246 I280 L281 I284L24-I222 HydrophobicContact CD1-CD1 4.27Å; L24-I222 HydrophobicContact CD1-CG1 3.89Å; L32-I222 HydrophobicContact CD1-CD1 4.17Å; L32-I222 HydrophobicContact CD1-CG1 4.11Å; Q33-I222 PolarHBondContact O-N 3.2Å; Q33-I222 VanDerWaalsContact O-N 3.16Å; I34-I222 HydrophobicContact CD1-CB 3.82Å; I34-I222 HydrophobicContact CD1-CD1 4.22Å; I34-I222 HydrophobicContact CD1-CG1 4.4Å; I35-I222 PolarHBondContact N-O 3.38Å; I222-L224 HydrophobicContact CG2-CD2 3.83Å; I222-L224 HydrophobicContact CG2-CG 4.3Å; I222-I246 HydrophobicContact CG2-CD1 4.31Å; I222-I280 HydrophobicContact CD1-CG2 4Å; I222-L281 HydrophobicContact CD1-CD2 3.95Å; I222-I284 HydrophobicContact CD1-CD1 4.01Å
223L98.9Very high95.8Very high0 Ų035.9 Ų35.90%017%0.174CC..EExtended strand (participates in β ladder)trans-104.8123.8176.7-174.6157.5000109.7I35 M233 A234 I243 L244 K245 I246 Y264I35-L223 CarbonylContact O-C 3.56Å; I35-L223 WeakPolarHBondContact O-CA 3.16Å; L223-M233 HydrophobicContact CD1-CB 4.44Å; L223-M233 HydrophobicContact CD2-CE 4.19Å; L223-M233 HydrophobicContact CG-CE 4.21Å; L223-A234 HydrophobicContact CD1-CB 3.93Å; L223-I243 HydrophobicContact CB-CD1 4.46Å; L223-I243 HydrophobicContact CD1-CD1 4.4Å; L223-L244 PolarHBondContact N-O 3Å; L223-K245 HydrophobicContact CB-CG 4.33Å; L223-I246 PolarHBondContact O-N 3.46Å; L223-Y264 HydrophobicContact CD2-CE1 4.2Å
224L98.9Very high96.1Very high0 Ų031.9 Ų31.90%015%0.154CC..EExtended strand (participates in β ladder)trans-114.8132.3175-48.7175.3000109.7I35 T36 D37 T41 F137 I222 M233 I246 A277I35-L224 PolarHBondContact O-N 3.05Å; T36-L224 WeakPolarHBondContact CA-O 3.24Å; T36-L224 WeakPolarHBondContact OG1-CB 3.32Å; D37-L224 PolarHBondContact N-O 3.22Å; T41-L224 HydrophobicContact CG2-CB 3.72Å; F137-L224 HydrophobicContact CE2-CD1 3.97Å; F137-L224 HydrophobicContact CZ-CD1 3.7Å; I222-L224 HydrophobicContact CG2-CD2 3.83Å; I222-L224 HydrophobicContact CG2-CG 4.3Å; L224-M233 VanDerWaalsContact O-CE 3.26Å; L224-M233 WeakPolarHBondContact O-CE 3.42Å; L224-I246 WeakPolarHBondContact CA-O 3.21Å; L224-I246 HydrophobicContact CD2-CB 3.68Å; L224-I246 HydrophobicContact CD2-CD1 3.8Å; L224-I246 HydrophobicContact CD2-CG1 4.02Å; L224-I246 HydrophobicContact CD2-CG2 4.34Å; L224-A277 HydrophobicContact CD2-CB 4.35Å
225G98.7Very high96.2Very high0 Ų028.1 Ų28.10%014%0.139CC..EExtended strand (participates in β ladder)trans-159.4171.6174.500000112.1T41 I246 G247 Y248T41-G225 VanDerWaalsContact OG1-CA 3.31Å; T41-G225 WeakPolarHBondContact OG1-CA 3.4Å; G225-I246 PolarHBondContact N-O 2.98Å; G225-I246 VanDerWaalsContact N-O 3.1Å; G225-G247 CarbonylContact O-C 2.95Å; G225-G247 VanDerWaalsContact O-CA 3.22Å; G225-G247 WeakPolarHBondContact O-CA 3.46Å; G225-Y248 PolarHBondContact O-N 3.3Å
226D97.9Very high96.1Very high33 Ų3327.3 Ų27.318%0.17614%0.136CC..SBendtrans-124.6-6.3178.369.2-66.1000112.5D39 T41 D230 Y248 Y260D39-D226 VanDerWaalsContact O-OD1 3.14Å; T41-D226 WeakPolarHBondContact OG1-CB 3.35Å; T41-D226 PolarHBondContact OG1-N 3.2Å; T41-D226 VanDerWaalsContact OG1-N 3.08Å; T41-D226 PolarHBondContact OG1-OD1 3.42Å; D226-D230 PolarHBondContact N-OD2 2.65Å; D226-Y248 VanDerWaalsContact CA-O 3.29Å; D226-Y248 WeakPolarHBondContact CA-O 3.32Å; D226-Y248 WeakPolarHBondContact CB-O 3.39Å; D226-Y260 WeakPolarHBondContact O-CE1 3.25Å; D226-Y260 PolarHBondContact O-OH 3.17Å
227S95.3Very high96.1Very high14 Ų1422.2 Ų22.210%0.09812%0.115CC..SBendtrans-121.9156.1179.579.60000112.4G229 D230 Y264S227-G229 PolarHBondContact O-N 3.12Å; S227-G229 VanDerWaalsContact O-N 3.16Å; S227-G229 PolarHBondContact OG-N 3.11Å; S227-D230 WeakPolarHBondContact CA-OD2 3.39Å; S227-D230 WeakPolarHBondContact CB-OD2 3.19Å; S227-D230 PolarHBondContact N-OD2 3.46Å; S227-D230 WeakPolarHBondContact O-CB 3.17Å; S227-D230 PolarHBondContact O-N 2.8Å; S227-D230 VanDerWaalsContact O-N 3.08Å; S227-D230 PolarHBondContact OG-N 3.21Å; S227-D230 PolarHBondContact OG-OD1 3.5Å; S227-D230 PolarHBondContact OG-OD2 3.29Å; S227-Y264 PolarHBondContact O-OH 3.34Å
228Q92.5Very high95.6Very high41 Ų4120 Ų2019%0.19211%0.113CC..G310 helixtrans-61.3-25.4174.3-65.9-68.3-53.200113.2D230 L231 K259 Y260 S263Q228-D230 VanDerWaalsContact C-N 3.27Å; Q228-D230 PolarHBondContact O-N 3.25Å; Q228-L231 WeakPolarHBondContact O-CB 3.47Å; Q228-K259 HydrophobicContact CG-CD 4.44Å; Q228-Y260 HydrophobicContact CG-CE2 4.27Å; Q228-Y260 VanDerWaalsContact NE2-CD2 3.28Å; Q228-S263 PolarHBondContact OE1-OG 2.81Å
229G92.5Very high95.3Very high7 Ų722.7 Ų22.77%0.07213%0.127CC..G310 helixtrans-69.8-24.7176.800000113.6V198 S227 L231 R232V198-G229 WeakPolarHBondContact O-CA 3.41Å; S227-G229 PolarHBondContact O-N 3.12Å; S227-G229 VanDerWaalsContact O-N 3.16Å; S227-G229 PolarHBondContact OG-N 3.11Å; G229-L231 PolarHBondContact O-N 2.9Å; G229-R232 WeakPolarHBondContact O-CB 3.22Å; G229-R232 PolarHBondContact O-N 2.91Å
230D97.2Very high95.3Very high1 Ų125.6 Ų25.61%0.00515%0.145CC..G310 helixtrans-69.1-23.6-178.9-62.1-37.8000112.8K201 D226 S227 Q228 R232 M233K201-D230 VanDerWaalsContact CE-OD1 3.29Å; K201-D230 WeakPolarHBondContact CE-OD1 3.4Å; K201-D230 IonicContact NZ-OD1 3.44Å; K201-D230 PolarHBondContact NZ-OD1 3.2Å; D226-D230 PolarHBondContact N-OD2 2.65Å; S227-D230 WeakPolarHBondContact CA-OD2 3.39Å; S227-D230 WeakPolarHBondContact CB-OD2 3.19Å; S227-D230 PolarHBondContact N-OD2 3.46Å; S227-D230 WeakPolarHBondContact O-CB 3.17Å; S227-D230 PolarHBondContact O-N 2.8Å; S227-D230 VanDerWaalsContact O-N 3.08Å; S227-D230 PolarHBondContact OG-N 3.21Å; S227-D230 PolarHBondContact OG-OD1 3.5Å; S227-D230 PolarHBondContact OG-OD2 3.29Å; Q228-D230 VanDerWaalsContact C-N 3.27Å; Q228-D230 PolarHBondContact O-N 3.25Å; D230-R232 PolarHBondContact O-N 3.4Å; D230-M233 HydrophobicContact CB-CE 3.63Å; D230-M233 HydrophobicContact CB-SD 4.19Å; D230-M233 WeakPolarHBondContact O-CB 3.5Å; D230-M233 WeakPolarHBondContact O-CE 3.45Å; D230-M233 VanDerWaalsContact O-CG 3.29Å; D230-M233 WeakPolarHBondContact O-CG 3.45Å; D230-M233 PolarHBondContact O-N 3.27Å
231L96.7Very high95.2Very high22 Ų2229.8 Ų29.812%0.11516%0.164CC..G310 helixtrans-57.6-17.9174.2-64.8169.3000113.1Q228 G229 K245 S263 Y264Q228-L231 WeakPolarHBondContact O-CB 3.47Å; G229-L231 PolarHBondContact O-N 2.9Å; L231-K245 HydrophobicContact CD2-CD 3.73Å; L231-S263 WeakPolarHBondContact CD2-O 3.12Å; L231-Y264 HydrophobicContact CD1-CE2 4.22Å; L231-Y264 HydrophobicContact CD2-CD1 3.83Å; L231-Y264 HydrophobicContact CD2-CD2 4.01Å; L231-Y264 HydrophobicContact CD2-CE1 3.55Å; L231-Y264 HydrophobicContact CD2-CE2 3.73Å; L231-Y264 HydrophobicContact CD2-CG 4.06Å; L231-Y264 VanDerWaalsContact CD2-CZ 3.49Å; L231-Y264 HydrophobicContact CG-CE1 4.34Å; L231-Y264 HydrophobicContact CG-CE2 3.94Å
232R95.7Very high95.2Very high114 Ų11432.7 Ų32.743%0.4318%0.178SC..G310 helixtrans-94.6-3-179.3-49-56.5-59.9-80.6-6.6113.8H202 G229 D230 A234 D235H202-R232 HydrophobicContact CB-CB 4.06Å; H202-R232 PolarHBondContact ND1-NH2 3.34Å; H202-R232 VanDerWaalsContact ND1-NH2 3.11Å; G229-R232 WeakPolarHBondContact O-CB 3.22Å; G229-R232 PolarHBondContact O-N 2.91Å; D230-R232 PolarHBondContact O-N 3.4Å; R232-A234 PolarHBondContact O-N 2.74Å; R232-D235 IonicContact CZ-OD2 3.68Å; R232-D235 IonicContact NE-OD1 2.71Å; R232-D235 IonicContact NE-OD2 2.91Å; R232-D235 PolarHBondContact NE-OD2 2.9Å; R232-D235 IonicContact NH2-OD2 3.36Å; R232-D235 PolarHBondContact NH2-OD2 3.41Å; R232-D235 WeakPolarHBondContact O-CB 3.17Å; R232-D235 PolarHBondContact O-N 2.85Å
233M97Very high95.2Very high0 Ų034.5 Ų34.50%019%0.187CC..THydrogen-bonded Turntrans-67.5-23.1-176.4-68.1-174.1-54.900113.6I35 D37 F151 K201 L223 L224 D230I35-M233 HydrophobicContact CG2-CB 3.51Å; I35-M233 HydrophobicContact CG2-CE 4.36Å; D37-M233 HydrophobicContact CB-CE 4.26Å; D37-M233 HydrophobicContact CB-SD 4.24Å; F151-M233 HydrophobicContact CB-CG 4.39Å; F151-M233 HydrophobicContact CB-SD 3.91Å; F151-M233 HydrophobicContact CD1-CB 4.01Å; F151-M233 HydrophobicContact CD1-CG 3.79Å; F151-M233 HydrophobicContact CD1-SD 4.38Å; F151-M233 HydrophobicContact CE1-CG 4.45Å; F151-M233 HydrophobicContact CG-CG 4.36Å; F151-M233 HydrophobicContact CG-SD 4.39Å; K201-M233 HydrophobicContact CB-CG 4.06Å; K201-M233 HydrophobicContact CD-CG 3.51Å; K201-M233 HydrophobicContact CD-SD 3.67Å; K201-M233 HydrophobicContact CG-CG 4.43Å; K201-M233 PolarHBondContact NZ-SD 2.93Å; K201-M233 VanDerWaalsContact NZ-SD 3.45Å; L223-M233 HydrophobicContact CD1-CB 4.44Å; L223-M233 HydrophobicContact CD2-CE 4.19Å; L223-M233 HydrophobicContact CG-CE 4.21Å; L224-M233 VanDerWaalsContact O-CE 3.26Å; L224-M233 WeakPolarHBondContact O-CE 3.42Å; D230-M233 HydrophobicContact CB-CE 3.63Å; D230-M233 HydrophobicContact CB-SD 4.19Å; D230-M233 WeakPolarHBondContact O-CB 3.5Å; D230-M233 WeakPolarHBondContact O-CE 3.45Å; D230-M233 VanDerWaalsContact O-CG 3.29Å; D230-M233 WeakPolarHBondContact O-CG 3.45Å; D230-M233 PolarHBondContact O-N 3.27Å
234A95.3Very high95.2Very high11 Ų1134.5 Ų34.59%0.09119%0.187CC..THydrogen-bonded Turntrans-90.74.3178.100000113.7I35 L223 R232 G236 V237 I243I35-A234 HydrophobicContact CD1-CB 3.92Å; L223-A234 HydrophobicContact CD1-CB 3.93Å; R232-A234 PolarHBondContact O-N 2.74Å; A234-G236 PolarHBondContact O-N 3.5Å; A234-G236 VanDerWaalsContact O-N 3.14Å; A234-V237 HydrophobicContact CB-CG2 4.13Å; A234-V237 WeakPolarHBondContact O-CB 3.26Å; A234-V237 VanDerWaalsContact O-CG2 3.31Å; A234-V237 WeakPolarHBondContact O-CG2 3.38Å; A234-V237 PolarHBondContact O-N 3.11Å; A234-I243 HydrophobicContact CB-CD1 3.83Å
235D93.2Very high95.2Very high57 Ų5737 Ų3731%0.30520%0.198SC..THydrogen-bonded Turntrans-65.8-19.8-174.9-71.58.6000113.3H202 A205 R232H202-D235 IonicContact CE1-OD2 2.69Å; H202-D235 IonicContact CG-OD2 2.83Å; H202-D235 WeakPolarHBondContact ND1-CB 3.29Å; H202-D235 IonicContact ND1-OD2 2.75Å; H202-D235 PolarHBondContact ND1-OD2 3.38Å; A205-D235 HydrophobicContact CB-CB 4.37Å; R232-D235 IonicContact CZ-OD2 3.68Å; R232-D235 IonicContact NE-OD1 2.71Å; R232-D235 IonicContact NE-OD2 2.91Å; R232-D235 PolarHBondContact NE-OD2 2.9Å; R232-D235 IonicContact NH2-OD2 3.36Å; R232-D235 PolarHBondContact NH2-OD2 3.41Å; R232-D235 WeakPolarHBondContact O-CB 3.17Å; R232-D235 PolarHBondContact O-N 2.85Å
236G90.8Very high95.2Very high7 Ų737 Ų377%0.07220%0.198CC..THydrogen-bonded Turntrans-83.6-5.7174.600000114.8F212 A234 A238F212-G236 WeakPolarHBondContact CB-O 3.39Å; F212-G236 WeakPolarHBondContact CD2-O 3.2Å; F212-G236 WeakPolarHBondContact CG-O 3.5Å; A234-G236 PolarHBondContact O-N 3.5Å; A234-G236 VanDerWaalsContact O-N 3.14Å; G236-A238 PolarHBondContact O-N 2.86Å
237V91.3Very high95.3Very high19 Ų1935.4 Ų35.412%0.11519%0.19CC..  trans-75122.9-177.5-178.30000110I35 F212 I221 A234 V240I35-V237 HydrophobicContact CD1-CG2 3.52Å; F212-V237 HydrophobicContact CD1-CG2 3.85Å; F212-V237 HydrophobicContact CE1-CG2 3.88Å; I221-V237 HydrophobicContact CD1-CG1 4.06Å; I221-V237 HydrophobicContact CG1-CG1 4.45Å; A234-V237 HydrophobicContact CB-CG2 4.13Å; A234-V237 WeakPolarHBondContact O-CB 3.26Å; A234-V237 VanDerWaalsContact O-CG2 3.31Å; A234-V237 WeakPolarHBondContact O-CG2 3.38Å; A234-V237 PolarHBondContact O-N 3.11Å; V237-V240 HydrophobicContact CB-CG2 4.08Å; V237-V240 HydrophobicContact CG1-CG2 3.75Å
238A84.1Confident95.4Very high66 Ų6634.8 Ų34.855%0.54519%0.185SC..SBendtrans-68.2-39-172.400000114.1G236G236-A238 PolarHBondContact O-N 2.86Å
239N91.6Very high95.7Very high80 Ų8032.9 Ų32.943%0.42818%0.176SC..  trans-138.5127.7-178.9-178.531.1000110.1S219S219-N239 WeakPolarHBondContact CA-O 3.34Å
240V96.8Very high95.9Very high63 Ų6333 Ų3338%0.38218%0.175SC..  trans-124.7109-179.6-179.40000108.7I221 V237 I243I221-V240 HydrophobicContact CD1-CB 4.15Å; I221-V240 HydrophobicContact CD1-CG1 3.76Å; I221-V240 HydrophobicContact CD1-CG2 3.8Å; V237-V240 HydrophobicContact CB-CG2 4.08Å; V237-V240 HydrophobicContact CG1-CG2 3.75Å; V240-I243 HydrophobicContact CG1-CB 3.79Å; V240-I243 HydrophobicContact CG1-CG2 3.8Å
241E97.8Very high95.7Very high88 Ų8836.1 Ų36.141%0.41119%0.192SC..SBendtrans-83.8-51.1170.3-79.2177.2-13600110.1K31 S219K31-E241 IonicContact NZ-OE1 2.59Å; K31-E241 PolarHBondContact NZ-OE1 2.73Å; K31-E241 IonicContact NZ-OE2 3.02Å; K31-E241 PolarHBondContact NZ-OE2 3.02Å; S219-E241 PolarHBondContact O-N 3.24Å; S219-E241 PolarHBondContact OG-OE1 3.5Å
242H98.6Very high95.4Very high62 Ų6237.7 Ų37.729%0.28720%0.196SC..EExtended strand (participates in β ladder)trans-137.7131.3179.1-58.8-61.2000110.2G23 L24 S219 N220 I221G23-H242 VanDerWaalsContact C-CD2 3.47Å; G23-H242 VanDerWaalsContact CA-CD2 3.41Å; G23-H242 WeakPolarHBondContact CA-CD2 3.3Å; G23-H242 WeakPolarHBondContact CA-NE2 3.46Å; L24-H242 HydrophobicContact CD2-CB 3.94Å; S219-H242 PolarHBondContact O-N 2.78Å; N220-H242 CarbonylContact C-O 3.53Å; N220-H242 VanDerWaalsContact CA-O 3.3Å; N220-H242 WeakPolarHBondContact CA-O 3.06Å; N220-H242 PolarHBondContact OD1-CD2 3.06Å; I221-H242 PolarHBondContact N-O 2.63Å
243I98.7Very high95.3Very high40 Ų4033.6 Ų33.621%0.20518%0.184CC..EExtended strand (participates in β ladder)trans-130125.9172.8-178.8166.6000109.1I221 L223 A234 V240 K245I221-I243 HydrophobicContact CB-CB 4.32Å; I221-I243 HydrophobicContact CB-CD1 4.34Å; I221-I243 HydrophobicContact CB-CG1 4.05Å; I221-I243 HydrophobicContact CG2-CD1 4.25Å; I221-I243 HydrophobicContact CG2-CG1 4.27Å; I221-I243 WeakPolarHBondContact O-CA 3.33Å; L223-I243 HydrophobicContact CB-CD1 4.46Å; L223-I243 HydrophobicContact CD1-CD1 4.4Å; A234-I243 HydrophobicContact CB-CD1 3.83Å; V240-I243 HydrophobicContact CG1-CB 3.79Å; V240-I243 HydrophobicContact CG1-CG2 3.8Å; I243-K245 HydrophobicContact CD1-CG 4.37Å; I243-K245 HydrophobicContact CG1-CG 4.13Å
244L98.9Very high95.2Very high0 Ų041.3 Ų41.30%023%0.225CC..EExtended strand (participates in β ladder)trans-107.6122.8171.6-176.367.6000109.2V17 I20 I21 L24 I221 L223 I246 D265 I266 I280V17-L244 HydrophobicContact CG1-CD1 4.38Å; I20-L244 HydrophobicContact CB-CD1 4.46Å; I20-L244 HydrophobicContact CG2-CB 3.72Å; I20-L244 HydrophobicContact CG2-CD1 4.02Å; I20-L244 HydrophobicContact CG2-CG 4.45Å; I21-L244 HydrophobicContact CD1-CD2 4.41Å; I21-L244 HydrophobicContact CG1-CD2 3.97Å; L24-L244 HydrophobicContact CD1-CB 3.91Å; L24-L244 HydrophobicContact CD1-CD2 4.17Å; I221-L244 PolarHBondContact O-N 2.59Å; L223-L244 PolarHBondContact N-O 3Å; L244-I246 HydrophobicContact CD2-CD1 4.23Å; L244-I246 HydrophobicContact CD2-CG1 4.36Å; L244-I246 HydrophobicContact CG-CG1 4.27Å; L244-D265 HydrophobicContact CD1-CB 3.86Å; L244-I266 HydrophobicContact CD1-CD1 4.21Å; L244-I266 HydrophobicContact CD1-CG1 4.41Å; L244-I266 HydrophobicContact CD2-CD1 4.23Å; L244-I280 HydrophobicContact CD2-CD1 3.66Å; L244-I280 HydrophobicContact CD2-CG2 4.47Å
245K98.9Very high95Very high52 Ų5246.7 Ų46.723%0.22625%0.248CC..EExtended strand (participates in β ladder)trans-105.1120.5179-56.5-177.8-179.7-173.40110.2L223 L231 I243 Y264 D265 I266L223-K245 HydrophobicContact CB-CG 4.33Å; L231-K245 HydrophobicContact CD2-CD 3.73Å; I243-K245 HydrophobicContact CD1-CG 4.37Å; I243-K245 HydrophobicContact CG1-CG 4.13Å; K245-Y264 HydrophobicContact CB-CD1 3.77Å; K245-Y264 HydrophobicContact CB-CE1 4.37Å; K245-D265 PolarHBondContact N-OD2 3.26Å; K245-D265 PolarHBondContact O-N 2.94Å; K245-I266 PolarHBondContact O-N 2.77Å; K245-I266 VanDerWaalsContact O-N 3.13Å
246I98.9Very high95Very high0 Ų045 Ų450%024%0.239CC..EExtended strand (participates in β ladder)trans-113.8121.2177.4-48.9-177.8000108.9I222 L223 L224 G225 L244 Y264 I266 L268 A277 I280I222-I246 HydrophobicContact CG2-CD1 4.31Å; L223-I246 PolarHBondContact O-N 3.46Å; L224-I246 WeakPolarHBondContact CA-O 3.21Å; L224-I246 HydrophobicContact CD2-CB 3.68Å; L224-I246 HydrophobicContact CD2-CD1 3.8Å; L224-I246 HydrophobicContact CD2-CG1 4.02Å; L224-I246 HydrophobicContact CD2-CG2 4.34Å; G225-I246 PolarHBondContact N-O 2.98Å; G225-I246 VanDerWaalsContact N-O 3.1Å; L244-I246 HydrophobicContact CD2-CD1 4.23Å; L244-I246 HydrophobicContact CD2-CG1 4.36Å; L244-I246 HydrophobicContact CG-CG1 4.27Å; I246-Y264 VanDerWaalsContact C-CD1 3.44Å; I246-I266 CarbonylContact C-O 3.55Å; I246-I266 WeakPolarHBondContact CA-O 3.48Å; I246-I266 HydrophobicContact CD1-CD1 4.5Å; I246-I266 HydrophobicContact CG1-CB 4.37Å; I246-I266 HydrophobicContact CG1-CD1 4.39Å; I246-I266 HydrophobicContact CG2-CB 4.34Å; I246-I266 HydrophobicContact CG2-CG2 4.38Å; I246-L268 HydrophobicContact CG2-CD1 3.64Å; I246-L268 HydrophobicContact CG2-CG 3.94Å; I246-A277 HydrophobicContact CD1-CB 4.41Å; I246-I280 HydrophobicContact CD1-CD1 3.87Å
247G98.8Very high95.3Very high0 Ų046 Ų460%024%0.242CC..EExtended strand (participates in β ladder)trans-111.9122.4-175.400000112.5G225 Y264 I266 V267 L268G225-G247 CarbonylContact O-C 2.95Å; G225-G247 VanDerWaalsContact O-CA 3.22Å; G225-G247 WeakPolarHBondContact O-CA 3.46Å; G247-Y264 VanDerWaalsContact CA-CD1 3.41Å; G247-I266 PolarHBondContact N-O 3.1Å; G247-V267 CarbonylContact O-C 3.48Å; G247-V267 WeakPolarHBondContact O-CA 3.35Å; G247-L268 PolarHBondContact O-N 3.48Å
248Y98.8Very high95.5Very high0 Ų052.1 Ų52.10%027%0.27CS..EExtended strand (participates in β ladder)trans-83.6114.4170.4-70.2-89.1000110.1T41 K131 G225 D226 L268 D271 S273 L274T41-Y248 HydrophobicContact CG2-CD2 4.14Å; T41-Y248 HydrophobicContact CG2-CE2 4.25Å; K131-Y248 HydrophobicContact CD-CD1 4.21Å; K131-Y248 HydrophobicContact CD-CE1 3.72Å; G225-Y248 PolarHBondContact O-N 3.3Å; D226-Y248 VanDerWaalsContact CA-O 3.29Å; D226-Y248 WeakPolarHBondContact CA-O 3.32Å; D226-Y248 WeakPolarHBondContact CB-O 3.39Å; Y248-L268 HydrophobicContact CD1-CB 3.95Å; Y248-L268 HydrophobicContact CD1-CD1 4.14Å; Y248-L268 HydrophobicContact CE1-CB 4.08Å; Y248-L268 HydrophobicContact CE1-CD1 3.48Å; Y248-L268 VanDerWaalsContact CE1-CD1 3.48Å; Y248-L268 HydrophobicContact CE1-CG 4.41Å; Y248-L268 HydrophobicContact CE2-CD1 4.27Å; Y248-D271 HydrophobicContact CD1-CB 4.48Å; Y248-D271 WeakPolarHBondContact CD1-O 3.43Å; Y248-D271 HydrophobicContact CE1-CB 4.38Å; Y248-S273 PolarHBondContact OH-O 2.7Å; Y248-L274 WeakPolarHBondContact OH-CD2 3.49Å
249L98.1Very high96Very high1 Ų154.1 Ų54.11%0.00527%0.266CS..EExtended strand (participates in β ladder)trans-9991.1174.3-179.856.7000109.1D251 V253 L256 L257 Y260 V267 L268 V269 Q270L249-D251 WeakPolarHBondContact CD1-O 3.24Å; L249-V253 HydrophobicContact CD2-CB 4.48Å; L249-V253 HydrophobicContact CD2-CG1 4.22Å; L249-V253 HydrophobicContact CG-CG2 4.33Å; L249-L256 HydrophobicContact CD1-CB 3.83Å; L249-L256 HydrophobicContact CD1-CD1 4.13Å; L249-L257 HydrophobicContact CD2-CB 3.89Å; L249-L257 HydrophobicContact CD2-CD1 3.95Å; L249-Y260 HydrophobicContact CB-CD1 4Å; L249-Y260 HydrophobicContact CB-CE1 4.27Å; L249-Y260 HydrophobicContact CB-CG 4.48Å; L249-Y260 HydrophobicContact CD1-CD1 4.19Å; L249-Y260 HydrophobicContact CD1-CD2 4.11Å; L249-Y260 HydrophobicContact CD1-CE1 4.06Å; L249-Y260 HydrophobicContact CD1-CE2 3.99Å; L249-Y260 HydrophobicContact CD1-CG 4.21Å; L249-Y260 HydrophobicContact CD2-CG 4.42Å; L249-V267 HydrophobicContact CB-CG1 3.81Å; L249-V267 HydrophobicContact CD2-CG1 4.36Å; L249-L268 PolarHBondContact N-O 3.01Å; L249-V269 HydrophobicContact CD2-CG2 4.48Å; L249-Q270 PolarHBondContact O-N 3.41Å
250N96.9Very high96.3Very high10 Ų1051.1 Ų51.15%0.05325%0.249CC..  trans-88.5-26.8-169.9-65.7-48.6000114.2M40 F45M40-N250 PolarHBondContact O-ND2 2.77Å; F45-N250 HydrophobicContact CB-CB 3.76Å; F45-N250 HydrophobicContact CD1-CB 4.01Å; F45-N250 HydrophobicContact CD2-CB 3.55Å; F45-N250 HydrophobicContact CE1-CB 4.48Å; F45-N250 HydrophobicContact CE2-CB 4.06Å; F45-N250 HydrophobicContact CG-CB 3.51Å
251D92.4Very high96.4Very high66 Ų6649.7 Ų49.735%0.35324%0.239SC..SBendtrans-143.2161.6-175.8-161.2-0.3000110.9F45 L249 V253F45-D251 HydrophobicContact CE2-CB 4.28Å; F45-D251 HydrophobicContact CZ-CB 3.81Å; L249-D251 WeakPolarHBondContact CD1-O 3.24Å; D251-V253 PolarHBondContact O-N 2.99Å
252R90.3Very high96.4Very high56 Ų5649.8 Ų49.821%0.21124%0.242CC..  trans48.944.9178.6-57.9-178.1-60.6136.61.1112.7V85 D254 E255 L256V85-R252 VanDerWaalsContact CA-NH2 3.28Å; V85-R252 VanDerWaalsContact CG1-NH2 3.27Å; V85-R252 PolarHBondContact O-NH1 3.02Å; V85-R252 PolarHBondContact O-NH2 3.25Å; R252-D254 VanDerWaalsContact C-N 3.32Å; R252-D254 PolarHBondContact O-N 3.3Å; R252-E255 HydrophobicContact CB-CB 4.38Å; R252-E255 IonicContact NH1-OE2 2.73Å; R252-E255 PolarHBondContact NH1-OE2 3.04Å; R252-E255 PolarHBondContact O-N 2.86Å; R252-E255 VanDerWaalsContact O-N 3.14Å; R252-L256 HydrophobicContact CB-CD1 4.11Å; R252-L256 HydrophobicContact CB-CG 4.31Å; R252-L256 WeakPolarHBondContact O-CB 3.25Å; R252-L256 PolarHBondContact O-N 3.41Å
253V94.6Very high96.3Very high27 Ų2748.8 Ų48.816%0.16424%0.242CC..Hα-helixtrans-52.9-50.7-174.3177.60000110.7L249 D251 E255 L256 L257 V269 Q270L249-V253 HydrophobicContact CD2-CB 4.48Å; L249-V253 HydrophobicContact CD2-CG1 4.22Å; L249-V253 HydrophobicContact CG-CG2 4.33Å; D251-V253 PolarHBondContact O-N 2.99Å; V253-E255 VanDerWaalsContact C-N 3.27Å; V253-E255 PolarHBondContact O-N 3.39Å; V253-L256 PolarHBondContact O-N 3.33Å; V253-L257 WeakPolarHBondContact O-CB 3.42Å; V253-L257 PolarHBondContact O-N 3.03Å; V253-V269 HydrophobicContact CB-CG1 4.31Å; V253-V269 HydrophobicContact CG1-CG1 3.51Å; V253-V269 HydrophobicContact CG2-CG1 3.76Å; V253-Q270 HydrophobicContact CG2-CG 3.98Å
254D93.9Very high96.3Very high162 Ų16247.2 Ų47.287%0.86623%0.234SC*.Hα-helixtrans-62.4-33.7-176-62.1-29.5000112.9R252R252-D254 VanDerWaalsContact C-N 3.32Å; R252-D254 PolarHBondContact O-N 3.3Å
255E92.6Very high96.3Very high125 Ų12548.3 Ų48.358%0.58424%0.24SC*.Hα-helixtrans-79.9-35.5-178.9-63.6172.4-16300112.7R252 V253R252-E255 HydrophobicContact CB-CB 4.38Å; R252-E255 IonicContact NH1-OE2 2.73Å; R252-E255 PolarHBondContact NH1-OE2 3.04Å; R252-E255 PolarHBondContact O-N 2.86Å; R252-E255 VanDerWaalsContact O-N 3.14Å; V253-E255 VanDerWaalsContact C-N 3.27Å; V253-E255 PolarHBondContact O-N 3.39Å
256L92Very high96.3Very high22 Ų2245.9 Ų45.912%0.11523%0.229CC..Hα-helixtrans-107.8-15.5-166.7-65179000114L249 R252 V253 E258 K259 Y260L249-L256 HydrophobicContact CD1-CB 3.83Å; L249-L256 HydrophobicContact CD1-CD1 4.13Å; R252-L256 HydrophobicContact CB-CD1 4.11Å; R252-L256 HydrophobicContact CB-CG 4.31Å; R252-L256 WeakPolarHBondContact O-CB 3.25Å; R252-L256 PolarHBondContact O-N 3.41Å; V253-L256 PolarHBondContact O-N 3.33Å; L256-E258 VanDerWaalsContact C-N 3.32Å; L256-E258 PolarHBondContact O-N 2.69Å; L256-K259 PolarHBondContact O-N 3.14Å; L256-K259 VanDerWaalsContact O-N 3.12Å; L256-Y260 HydrophobicContact CB-CD2 3.92Å; L256-Y260 HydrophobicContact CB-CE2 3.96Å; L256-Y260 HydrophobicContact CD1-CE2 4.1Å; L256-Y260 VanDerWaalsContact O-CD2 3.31Å; L256-Y260 WeakPolarHBondContact O-CD2 3.32Å; L256-Y260 PolarHBondContact O-N 2.82Å
257L96.6Very high96.3Very high26 Ų2645.9 Ų45.914%0.13623%0.229CC..Hα-helixtrans-56-45.1-171.7175.465.7000112.8R10 L249 V253 Y260 M261 V267 V269R10-L257 HydrophobicContact CB-CD1 4.32Å; R10-L257 HydrophobicContact CG-CD1 4.18Å; R10-L257 VanDerWaalsContact NH1-CD2 3.29Å; L249-L257 HydrophobicContact CD2-CB 3.89Å; L249-L257 HydrophobicContact CD2-CD1 3.95Å; V253-L257 WeakPolarHBondContact O-CB 3.42Å; V253-L257 PolarHBondContact O-N 3.03Å; L257-Y260 PolarHBondContact O-N 3.49Å; L257-M261 HydrophobicContact CD1-CG 3.88Å; L257-M261 HydrophobicContact CD1-SD 3.9Å; L257-M261 HydrophobicContact CD2-SD 4.49Å; L257-M261 HydrophobicContact CG-CG 4.3Å; L257-M261 HydrophobicContact CG-SD 3.99Å; L257-M261 WeakPolarHBondContact O-CB 3.27Å; L257-M261 VanDerWaalsContact O-CG 3.3Å; L257-M261 WeakPolarHBondContact O-CG 3.43Å; L257-M261 PolarHBondContact O-N 2.79Å; L257-V267 HydrophobicContact CD1-CG1 4.28Å; L257-V269 HydrophobicContact CD1-CG2 3.87Å
258E96.7Very high96.3Very high149 Ų14945.9 Ų45.970%0.69623%0.229SC*.Hα-helixtrans-60.1-49.2178.3-175.2172.5-161.300111L256 Y260 M261 D262L256-E258 VanDerWaalsContact C-N 3.32Å; L256-E258 PolarHBondContact O-N 2.69Å; E258-Y260 VanDerWaalsContact C-N 3.29Å; E258-Y260 PolarHBondContact O-N 3.44Å; E258-M261 PolarHBondContact O-N 3.06Å; E258-D262 WeakPolarHBondContact O-CB 3.29Å; E258-D262 VanDerWaalsContact O-CG 3.26Å; E258-D262 PolarHBondContact O-N 3.35Å
259K94.3Very high96.3Very high108 Ų10846.9 Ų46.947%0.4724%0.235SC..Hα-helixtrans-59.4-38.9177.3-174.1174.4-175.3174.10112.7Q228 L256 S263Q228-K259 HydrophobicContact CG-CD 4.44Å; L256-K259 PolarHBondContact O-N 3.14Å; L256-K259 VanDerWaalsContact O-N 3.12Å; K259-S263 WeakPolarHBondContact O-CB 3.34Å; K259-S263 PolarHBondContact O-N 3.24Å; K259-S263 PolarHBondContact O-OG 3.49Å
260Y97.5Very high96.3Very high16 Ų1653.1 Ų53.16%0.06326%0.264CS..Hα-helixtrans-69.1-45.2176.6-87.2-118.7000111.2D226 Q228 L249 L256 L257 E258 D262 S263 Y264 V267D226-Y260 WeakPolarHBondContact O-CE1 3.25Å; D226-Y260 PolarHBondContact O-OH 3.17Å; Q228-Y260 HydrophobicContact CG-CE2 4.27Å; Q228-Y260 VanDerWaalsContact NE2-CD2 3.28Å; L249-Y260 HydrophobicContact CB-CD1 4Å; L249-Y260 HydrophobicContact CB-CE1 4.27Å; L249-Y260 HydrophobicContact CB-CG 4.48Å; L249-Y260 HydrophobicContact CD1-CD1 4.19Å; L249-Y260 HydrophobicContact CD1-CD2 4.11Å; L249-Y260 HydrophobicContact CD1-CE1 4.06Å; L249-Y260 HydrophobicContact CD1-CE2 3.99Å; L249-Y260 HydrophobicContact CD1-CG 4.21Å; L249-Y260 HydrophobicContact CD2-CG 4.42Å; L256-Y260 HydrophobicContact CB-CD2 3.92Å; L256-Y260 HydrophobicContact CB-CE2 3.96Å; L256-Y260 HydrophobicContact CD1-CE2 4.1Å; L256-Y260 VanDerWaalsContact O-CD2 3.31Å; L256-Y260 WeakPolarHBondContact O-CD2 3.32Å; L256-Y260 PolarHBondContact O-N 2.82Å; L257-Y260 PolarHBondContact O-N 3.49Å; E258-Y260 VanDerWaalsContact C-N 3.29Å; E258-Y260 PolarHBondContact O-N 3.44Å; Y260-D262 PolarHBondContact O-N 3.11Å; Y260-S263 PolarHBondContact O-N 3.29Å; Y260-S263 VanDerWaalsContact O-N 3.09Å; Y260-Y264 HydrophobicContact CD1-CD2 4.05Å; Y260-Y264 HydrophobicContact CD1-CE2 4.14Å; Y260-Y264 HydrophobicContact CE1-CE2 4.29Å; Y260-Y264 WeakPolarHBondContact O-CB 3.42Å; Y260-Y264 PolarHBondContact O-N 3.1Å; Y260-V267 HydrophobicContact CD1-CG1 4.49Å
261M98.4Very high96.4Very high33 Ų3353.2 Ų53.216%0.16327%0.265CS..Hα-helixtrans-64.5-23.9177.8-74.5-171.969.300113R10 K12 L257 E258 V267R10-M261 HydrophobicContact CB-CE 4.31Å; R10-M261 HydrophobicContact CB-CG 4.29Å; R10-M261 HydrophobicContact CB-SD 3.97Å; K12-M261 HydrophobicContact CB-CB 4.31Å; K12-M261 HydrophobicContact CB-CE 4.05Å; K12-M261 VanDerWaalsContact CB-O 3.28Å; K12-M261 WeakPolarHBondContact CB-O 3.42Å; K12-M261 WeakPolarHBondContact CD-O 3.32Å; L257-M261 HydrophobicContact CD1-CG 3.88Å; L257-M261 HydrophobicContact CD1-SD 3.9Å; L257-M261 HydrophobicContact CD2-SD 4.49Å; L257-M261 HydrophobicContact CG-CG 4.3Å; L257-M261 HydrophobicContact CG-SD 3.99Å; L257-M261 WeakPolarHBondContact O-CB 3.27Å; L257-M261 VanDerWaalsContact O-CG 3.3Å; L257-M261 WeakPolarHBondContact O-CG 3.43Å; L257-M261 PolarHBondContact O-N 2.79Å; E258-M261 PolarHBondContact O-N 3.06Å; M261-V267 HydrophobicContact CG-CB 4.48Å; M261-V267 HydrophobicContact CG-CG2 4.04Å
262D98.1Very high96.6Very high90 Ų9051.6 Ų51.648%0.48126%0.255SS..Hα-helixtrans-79.5-25.8175.1-75.58.6000113.2K12 E258 Y260K12-D262 WeakPolarHBondContact CD-OD1 3.45Å; K12-D262 WeakPolarHBondContact CE-OD1 3.45Å; K12-D262 VanDerWaalsContact NZ-CG 3.33Å; K12-D262 IonicContact NZ-OD1 2.74Å; K12-D262 PolarHBondContact NZ-OD1 3.38Å; K12-D262 IonicContact NZ-OD2 3.58Å; E258-D262 WeakPolarHBondContact O-CB 3.29Å; E258-D262 VanDerWaalsContact O-CG 3.26Å; E258-D262 PolarHBondContact O-N 3.35Å; Y260-D262 PolarHBondContact O-N 3.11Å
263S97.2Very high97Very high42 Ų4249.2 Ų49.229%0.29425%0.247SC..Hα-helixtrans-111.9-27.6-168.1-48.30000113.9Q228 L231 K259 Y260Q228-S263 PolarHBondContact OE1-OG 2.81Å; L231-S263 WeakPolarHBondContact CD2-O 3.12Å; K259-S263 WeakPolarHBondContact O-CB 3.34Å; K259-S263 PolarHBondContact O-N 3.24Å; K259-S263 PolarHBondContact O-OG 3.49Å; Y260-S263 PolarHBondContact O-N 3.29Å; Y260-S263 VanDerWaalsContact O-N 3.09Å
264Y98.8Very high97.3Very high6 Ų647.9 Ų47.92%0.02424%0.239CC..  trans-107.4143.8174.2-74.5-86.4000110.6L223 S227 L231 K245 I246 G247 Y260L223-Y264 HydrophobicContact CD2-CE1 4.2Å; S227-Y264 PolarHBondContact O-OH 3.34Å; L231-Y264 HydrophobicContact CD1-CE2 4.22Å; L231-Y264 HydrophobicContact CD2-CD1 3.83Å; L231-Y264 HydrophobicContact CD2-CD2 4.01Å; L231-Y264 HydrophobicContact CD2-CE1 3.55Å; L231-Y264 HydrophobicContact CD2-CE2 3.73Å; L231-Y264 HydrophobicContact CD2-CG 4.06Å; L231-Y264 VanDerWaalsContact CD2-CZ 3.49Å; L231-Y264 HydrophobicContact CG-CE1 4.34Å; L231-Y264 HydrophobicContact CG-CE2 3.94Å; K245-Y264 HydrophobicContact CB-CD1 3.77Å; K245-Y264 HydrophobicContact CB-CE1 4.37Å; I246-Y264 VanDerWaalsContact C-CD1 3.44Å; G247-Y264 VanDerWaalsContact CA-CD1 3.41Å; Y260-Y264 HydrophobicContact CD1-CD2 4.05Å; Y260-Y264 HydrophobicContact CD1-CE2 4.14Å; Y260-Y264 HydrophobicContact CE1-CE2 4.29Å; Y260-Y264 WeakPolarHBondContact O-CB 3.42Å; Y260-Y264 PolarHBondContact O-N 3.1Å
265D98.8Very high97.5Very high24 Ų2443.4 Ų43.413%0.12821%0.213CC..SBendtrans-71.9-37.9177.5-55.2-70.1000110.8R16 V17 L244 K245R16-D265 IonicContact NE-OD1 2.85Å; V17-D265 HydrophobicContact CG2-CB 3.87Å; V17-D265 WeakPolarHBondContact CG2-O 3.3Å; L244-D265 HydrophobicContact CD1-CB 3.86Å; K245-D265 PolarHBondContact N-OD2 3.26Å; K245-D265 PolarHBondContact O-N 2.94Å
266I98.9Very high97.8Very high0 Ų037.5 Ų37.50%019%0.185CC..EExtended strand (participates in β ladder)trans-126.6126.8175.1-54.4175.3000108.9F4 V9 I11 V17 L244 K245 I246 G247 L268 V276 I280F4-I266 HydrophobicContact CE1-CD1 3.67Å; F4-I266 HydrophobicContact CZ-CD1 3.98Å; V9-I266 HydrophobicContact CG1-CG2 4.24Å; I11-I266 HydrophobicContact CD1-CG1 4.14Å; I11-I266 HydrophobicContact CD1-CG2 4.45Å; I11-I266 HydrophobicContact CG1-CB 4.38Å; I11-I266 HydrophobicContact CG1-CG1 4.12Å; I11-I266 HydrophobicContact CG1-CG2 4.17Å; V17-I266 HydrophobicContact CG1-CD1 3.92Å; V17-I266 HydrophobicContact CG1-CG1 4.02Å; V17-I266 HydrophobicContact CG2-CG1 4.11Å; L244-I266 HydrophobicContact CD1-CD1 4.21Å; L244-I266 HydrophobicContact CD1-CG1 4.41Å; L244-I266 HydrophobicContact CD2-CD1 4.23Å; K245-I266 PolarHBondContact O-N 2.77Å; K245-I266 VanDerWaalsContact O-N 3.13Å; I246-I266 CarbonylContact C-O 3.55Å; I246-I266 WeakPolarHBondContact CA-O 3.48Å; I246-I266 HydrophobicContact CD1-CD1 4.5Å; I246-I266 HydrophobicContact CG1-CB 4.37Å; I246-I266 HydrophobicContact CG1-CD1 4.39Å; I246-I266 HydrophobicContact CG2-CB 4.34Å; I246-I266 HydrophobicContact CG2-CG2 4.38Å; G247-I266 PolarHBondContact N-O 3.1Å; I266-L268 HydrophobicContact CG2-CD2 4.01Å; I266-L268 HydrophobicContact CG2-CG 4.48Å; I266-V276 HydrophobicContact CD1-CG1 4.41Å; I266-V276 HydrophobicContact CG2-CG1 4.45Å; I266-I280 HydrophobicContact CD1-CD1 4.23Å
267V98.9Very high98.1Very high0 Ų036.5 Ų36.50%018%0.18CC..EExtended strand (participates in β ladder)trans-109.4130.1172.8-178.90000109.4R10 G247 L249 L257 Y260 M261 V269R10-V267 HydrophobicContact CB-CB 4.23Å; R10-V267 PolarHBondContact N-O 2.85Å; R10-V267 PolarHBondContact O-N 2.85Å; G247-V267 CarbonylContact O-C 3.48Å; G247-V267 WeakPolarHBondContact O-CA 3.35Å; L249-V267 HydrophobicContact CB-CG1 3.81Å; L249-V267 HydrophobicContact CD2-CG1 4.36Å; L257-V267 HydrophobicContact CD1-CG1 4.28Å; Y260-V267 HydrophobicContact CD1-CG1 4.49Å; M261-V267 HydrophobicContact CG-CB 4.48Å; M261-V267 HydrophobicContact CG-CG2 4.04Å; V267-V269 HydrophobicContact CG1-CG2 4.15Å
268L98.9Very high98.2Very high1 Ų135.9 Ų35.91%0.00518%0.177CC..EExtended strand (participates in β ladder)trans-108.7101.5177.4-58.2-179.9000108.9S8 V9 I246 G247 Y248 L249 I266 D271 V276S8-L268 WeakPolarHBondContact O-CA 3.5Å; V9-L268 HydrophobicContact CG2-CD2 3.83Å; I246-L268 HydrophobicContact CG2-CD1 3.64Å; I246-L268 HydrophobicContact CG2-CG 3.94Å; G247-L268 PolarHBondContact O-N 3.48Å; Y248-L268 HydrophobicContact CD1-CB 3.95Å; Y248-L268 HydrophobicContact CD1-CD1 4.14Å; Y248-L268 HydrophobicContact CE1-CB 4.08Å; Y248-L268 HydrophobicContact CE1-CD1 3.48Å; Y248-L268 VanDerWaalsContact CE1-CD1 3.48Å; Y248-L268 HydrophobicContact CE1-CG 4.41Å; Y248-L268 HydrophobicContact CE2-CD1 4.27Å; L249-L268 PolarHBondContact N-O 3.01Å; I266-L268 HydrophobicContact CG2-CD2 4.01Å; I266-L268 HydrophobicContact CG2-CG 4.48Å; L268-D271 HydrophobicContact CB-CB 3.85Å; L268-V276 HydrophobicContact CD1-CB 4.38Å; L268-V276 HydrophobicContact CD2-CB 4.22Å; L268-V276 HydrophobicContact CD2-CG1 4.46Å; L268-V276 HydrophobicContact CD2-CG2 3.83Å
269V98.7Very high98.3Very high21 Ų2129.2 Ų29.213%0.12715%0.147CC..EExtended strand (participates in β ladder)trans-82.6117-176.3-179.60000109.6S8 R10 L249 V253 L257 V267 D271S8-V269 VanDerWaalsContact CB-O 3.25Å; S8-V269 WeakPolarHBondContact CB-O 3.46Å; S8-V269 PolarHBondContact O-N 3.08Å; R10-V269 HydrophobicContact CG-CG2 3.72Å; L249-V269 HydrophobicContact CD2-CG2 4.48Å; V253-V269 HydrophobicContact CB-CG1 4.31Å; V253-V269 HydrophobicContact CG1-CG1 3.51Å; V253-V269 HydrophobicContact CG2-CG1 3.76Å; L257-V269 HydrophobicContact CD1-CG2 3.87Å; V267-V269 HydrophobicContact CG1-CG2 4.15Å; V269-D271 PolarHBondContact O-N 3.07Å
270Q97.9Very high98.5Very high132 Ų13224.1 Ų24.162%0.61713%0.125SC*.THydrogen-bonded Turntrans50.139.6177.9-60-179.2-45.400113.3L249 V253L249-Q270 PolarHBondContact O-N 3.41Å; V253-Q270 HydrophobicContact CG2-CG 3.98Å
271D98.3Very high98.5Very high11 Ų1123.3 Ų23.36%0.05912%0.122CC..  trans-97.3124.3-179.4-157.3-50.5000110.7S8 K131 Y248 L268 V269 S273S8-D271 WeakPolarHBondContact CB-OD2 3.38Å; S8-D271 PolarHBondContact OG-OD2 3.47Å; K131-D271 PolarHBondContact NZ-O 3.14Å; Y248-D271 HydrophobicContact CD1-CB 4.48Å; Y248-D271 WeakPolarHBondContact CD1-O 3.43Å; Y248-D271 HydrophobicContact CE1-CB 4.38Å; L268-D271 HydrophobicContact CB-CB 3.85Å; V269-D271 PolarHBondContact O-N 3.07Å; D271-S273 WeakPolarHBondContact OD1-CA 3.43Å; D271-S273 WeakPolarHBondContact OD1-CB 3.45Å; D271-S273 PolarHBondContact OD1-N 2.79Å; D271-S273 PolarHBondContact OD1-OG 2.98Å
272E98.4Very high98.5Very high33 Ų3327.2 Ų27.215%0.15414%0.139CC..  trans-103.320.6179.2-58.5-67.4-166.100112.9R44 F45 S46 K131 E132R44-E272 WeakPolarHBondContact CA-OE2 3.33Å; R44-E272 WeakPolarHBondContact CB-OE2 3.47Å; R44-E272 HydrophobicContact CG-CB 4.33Å; F45-E272 WeakPolarHBondContact CA-OE1 3.34Å; F45-E272 WeakPolarHBondContact CB-OE1 3.47Å; F45-E272 PolarHBondContact N-OE1 3.02Å; F45-E272 VanDerWaalsContact N-OE1 3.09Å; F45-E272 PolarHBondContact N-OE2 3.17Å; S46-E272 PolarHBondContact N-OE1 3.21Å; S46-E272 PolarHBondContact OG-OE1 3.31Å; K131-E272 CarbonylContact C-O 3.59Å; K131-E272 VanDerWaalsContact CA-O 3.29Å; K131-E272 WeakPolarHBondContact CA-O 3.31Å; K131-E272 WeakPolarHBondContact CB-O 3.47Å; K131-E272 IonicContact NZ-OE2 3.76Å; K131-E272 PolarHBondContact NZ-OE2 2.71Å; E132-E272 PolarHBondContact N-O 3.1Å
273S98.6Very high98.5Very high5 Ų528.9 Ų28.94%0.03514%0.142CC..BIsolated β-bridgetrans-121.7159.1179.2790000112.5E132 Y248 D271E132-S273 WeakPolarHBondContact O-CA 3.35Å; Y248-S273 PolarHBondContact OH-O 2.7Å; D271-S273 WeakPolarHBondContact OD1-CA 3.43Å; D271-S273 WeakPolarHBondContact OD1-CB 3.45Å; D271-S273 PolarHBondContact OD1-N 2.79Å; D271-S273 PolarHBondContact OD1-OG 2.98Å
274L98.8Very high98.6Very high0 Ų027.5 Ų27.50%013%0.132CC..  trans-100.816.1169-65171.8000111.7L42 K131 E132 F137 Y248 V276 A277 N278L42-L274 HydrophobicContact CD2-CD1 4.22Å; L42-L274 HydrophobicContact CD2-CD2 4.26Å; K131-L274 HydrophobicContact CB-CD2 4.45Å; K131-L274 HydrophobicContact CB-CG 3.96Å; K131-L274 HydrophobicContact CD-CD2 4.37Å; E132-L274 PolarHBondContact O-N 2.62Å; F137-L274 HydrophobicContact CB-CD1 3.86Å; F137-L274 HydrophobicContact CD1-CD1 4.25Å; F137-L274 HydrophobicContact CD2-CD1 4.41Å; F137-L274 HydrophobicContact CG-CD1 3.93Å; Y248-L274 WeakPolarHBondContact OH-CD2 3.49Å; L274-V276 VanDerWaalsContact C-N 3.35Å; L274-V276 PolarHBondContact O-N 3.39Å; L274-A277 PolarHBondContact O-N 3.32Å; L274-N278 WeakPolarHBondContact O-CB 3.39Å; L274-N278 PolarHBondContact O-N 3.18Å
275E98.4Very high98.5Very high67 Ų6729.7 Ų29.731%0.31314%0.143SC..Hα-helixtrans-59.6-40.7-171.5-78.6-178.8-129.700113.5K6 N278 S279K6-E275 WeakPolarHBondContact CE-OE2 3.37Å; K6-E275 IonicContact NZ-OE1 2.66Å; K6-E275 PolarHBondContact NZ-OE1 3.28Å; K6-E275 IonicContact NZ-OE2 3.52Å; K6-E275 PolarHBondContact NZ-OE2 3.19Å; E275-N278 PolarHBondContact O-N 3.06Å; E275-S279 VanDerWaalsContact O-CB 3.31Å; E275-S279 WeakPolarHBondContact O-CB 3.43Å; E275-S279 PolarHBondContact O-N 3.13Å; E275-S279 PolarHBondContact O-OG 2.85Å
276V98.7Very high98.5Very high2 Ų230 Ų301%0.01214%0.144CC..Hα-helixtrans-62.9-48.5177.8174.50000110.4E3 F4 V9 I266 L268 L274 N278 S279 I280E3-V276 HydrophobicContact CB-CG2 4.34Å; F4-V276 HydrophobicContact CD2-CG1 4.48Å; F4-V276 HydrophobicContact CE2-CG1 3.94Å; F4-V276 HydrophobicContact CZ-CG1 4.02Å; V9-V276 HydrophobicContact CG2-CG2 3.9Å; I266-V276 HydrophobicContact CD1-CG1 4.41Å; I266-V276 HydrophobicContact CG2-CG1 4.45Å; L268-V276 HydrophobicContact CD1-CB 4.38Å; L268-V276 HydrophobicContact CD2-CB 4.22Å; L268-V276 HydrophobicContact CD2-CG1 4.46Å; L268-V276 HydrophobicContact CD2-CG2 3.83Å; L274-V276 VanDerWaalsContact C-N 3.35Å; L274-V276 PolarHBondContact O-N 3.39Å; V276-N278 PolarHBondContact O-N 3.38Å; V276-S279 PolarHBondContact O-N 3.43Å; V276-S279 PolarHBondContact O-OG 2.94Å; V276-I280 HydrophobicContact CG1-CD1 4.13Å; V276-I280 WeakPolarHBondContact O-CD1 3.26Å; V276-I280 WeakPolarHBondContact O-CG1 3.38Å; V276-I280 PolarHBondContact O-N 3.01Å; V276-I280 VanDerWaalsContact O-N 3.14Å
277A98.6Very high98.4Very high1 Ų131.6 Ų31.61%0.00815%0.152CC..Hα-helixtrans-60.7-45.8176.100000111.6F137 L224 I246 L274 S279 I280 L281F137-A277 HydrophobicContact CD2-CB 4.48Å; F137-A277 HydrophobicContact CE2-CB 4.25Å; L224-A277 HydrophobicContact CD2-CB 4.35Å; I246-A277 HydrophobicContact CD1-CB 4.41Å; L274-A277 PolarHBondContact O-N 3.32Å; A277-S279 VanDerWaalsContact C-N 3.33Å; A277-S279 PolarHBondContact O-N 2.88Å; A277-I280 WeakPolarHBondContact O-CB 2.83Å; A277-I280 PolarHBondContact O-N 3.24Å; A277-L281 WeakPolarHBondContact O-CG 3.17Å; A277-L281 PolarHBondContact O-N 2.85Å
278N98.8Very high98.4Very high12 Ų1233.3 Ų33.36%0.06416%0.16CC..Hα-helixtrans-60.4-39.9177-78.6-22.2000112.7G133 F137 L274 E275 V276 I280 L281 Q282G133-N278 PolarHBondContact O-ND2 2.79Å; F137-N278 WeakPolarHBondContact CA-OD1 3.4Å; F137-N278 VanDerWaalsContact CB-OD1 3.27Å; F137-N278 WeakPolarHBondContact CB-OD1 3.34Å; F137-N278 PolarHBondContact N-OD1 3.3Å; L274-N278 WeakPolarHBondContact O-CB 3.39Å; L274-N278 PolarHBondContact O-N 3.18Å; E275-N278 PolarHBondContact O-N 3.06Å; V276-N278 PolarHBondContact O-N 3.38Å; N278-I280 VanDerWaalsContact C-N 3.31Å; N278-I280 PolarHBondContact O-N 3.47Å; N278-L281 PolarHBondContact O-N 2.98Å; N278-Q282 WeakPolarHBondContact O-CB 3.36Å; N278-Q282 PolarHBondContact O-N 3.46Å
279S98.6Very high98.4Very high10 Ų1035.2 Ų35.27%0.0717%0.169CC..Hα-helixtrans-65.8-35.2177.774.70000112.1M1 E3 E275 V276 A277 Q282 K283M1-S279 VanDerWaalsContact CE-C 3.42Å; M1-S279 VanDerWaalsContact CE-O 3.31Å; M1-S279 WeakPolarHBondContact CE-O 3.27Å; M1-S279 WeakPolarHBondContact CE-OG 3.41Å; E3-S279 VanDerWaalsContact CD-CB 3.44Å; E275-S279 VanDerWaalsContact O-CB 3.31Å; E275-S279 WeakPolarHBondContact O-CB 3.43Å; E275-S279 PolarHBondContact O-N 3.13Å; E275-S279 PolarHBondContact O-OG 2.85Å; V276-S279 PolarHBondContact O-N 3.43Å; V276-S279 PolarHBondContact O-OG 2.94Å; A277-S279 VanDerWaalsContact C-N 3.33Å; A277-S279 PolarHBondContact O-N 2.88Å; S279-Q282 PolarHBondContact O-N 2.81Å; S279-K283 WeakPolarHBondContact O-CG 3.29Å; S279-K283 PolarHBondContact O-N 2.85Å
280I98.8Very high98.4Very high0 Ų036.1 Ų36.10%017%0.172CC..Hα-helixtrans-68.7-49.2174-65.4157.9000109.8M1 F4 I21 L24 I222 L244 I246 I266 V276 A277 N278 Q282 K283 I284M1-I280 HydrophobicContact CE-CG1 4.35Å; F4-I280 HydrophobicContact CE2-CD1 4.45Å; F4-I280 HydrophobicContact CE2-CG1 4.11Å; F4-I280 HydrophobicContact CZ-CD1 3.91Å; F4-I280 HydrophobicContact CZ-CG1 3.86Å; I21-I280 HydrophobicContact CD1-CD1 4.38Å; I21-I280 HydrophobicContact CD1-CG1 4.16Å; L24-I280 HydrophobicContact CD1-CG2 4.47Å; I222-I280 HydrophobicContact CD1-CG2 4Å; L244-I280 HydrophobicContact CD2-CD1 3.66Å; L244-I280 HydrophobicContact CD2-CG2 4.47Å; I246-I280 HydrophobicContact CD1-CD1 3.87Å; I266-I280 HydrophobicContact CD1-CD1 4.23Å; V276-I280 HydrophobicContact CG1-CD1 4.13Å; V276-I280 WeakPolarHBondContact O-CD1 3.26Å; V276-I280 WeakPolarHBondContact O-CG1 3.38Å; V276-I280 PolarHBondContact O-N 3.01Å; V276-I280 VanDerWaalsContact O-N 3.14Å; A277-I280 WeakPolarHBondContact O-CB 2.83Å; A277-I280 PolarHBondContact O-N 3.24Å; N278-I280 VanDerWaalsContact C-N 3.31Å; N278-I280 PolarHBondContact O-N 3.47Å; I280-Q282 PolarHBondContact O-N 3.07Å; I280-K283 PolarHBondContact O-N 2.66Å; I280-I284 HydrophobicContact CG2-CD1 3.63Å; I280-I284 HydrophobicContact CG2-CG1 4.41Å; I280-I284 WeakPolarHBondContact O-CG1 3.32Å; I280-I284 PolarHBondContact O-N 3.45Å; I280-I284 VanDerWaalsContact O-N 3.15Å
281L98.7Very high98.4Very high0 Ų029.7 Ų29.70%014%0.142CC..Hα-helixtrans-56.8-36.8175.7-68.3175.8000111.6L32 I34 F137 K140 L141 I222 A277 N278 K283 I284 L285L32-L281 HydrophobicContact CD2-CD2 3.85Å; I34-L281 HydrophobicContact CD1-CD2 4.24Å; F137-L281 HydrophobicContact CD2-CD1 3.65Å; F137-L281 HydrophobicContact CE2-CD1 3.78Å; K140-L281 WeakPolarHBondContact CE-O 3.21Å; L141-L281 HydrophobicContact CD1-CD1 4.32Å; L141-L281 HydrophobicContact CD2-CD1 3.96Å; L141-L281 HydrophobicContact CD2-CD2 3.82Å; L141-L281 HydrophobicContact CG-CD1 4.06Å; I222-L281 HydrophobicContact CD1-CD2 3.95Å; A277-L281 WeakPolarHBondContact O-CG 3.17Å; A277-L281 PolarHBondContact O-N 2.85Å; N278-L281 PolarHBondContact O-N 2.98Å; L281-K283 PolarHBondContact O-N 2.85Å; L281-I284 PolarHBondContact O-N 2.97Å; L281-L285 HydrophobicContact CB-CD1 4.48Å; L281-L285 HydrophobicContact CD2-CD1 4.23Å; L281-L285 WeakPolarHBondContact O-CB 3.44Å; L281-L285 PolarHBondContact O-N 3.16Å
282Q98.3Very high98.4Very high114 Ų11431.1 Ų31.153%0.53315%0.148SC..Hα-helixtrans-65-21.6176.3-174.255.35400114.2K140 N278 S279 I280K140-Q282 VanDerWaalsContact NZ-CD 3.28Å; N278-Q282 WeakPolarHBondContact O-CB 3.36Å; N278-Q282 PolarHBondContact O-N 3.46Å; S279-Q282 PolarHBondContact O-N 2.81Å; I280-Q282 PolarHBondContact O-N 3.07Å
283K98.2Very high98.4Very high125 Ų12530.9 Ų30.954%0.54315%0.148SC..Hα-helixtrans-90.3-28.3174.6-62.6-61.5-176.5-175.70112.8M1 I25 S279 I280 L281M1-K283 HydrophobicContact CE-CG 4.14Å; M1-K283 HydrophobicContact SD-CG 4.4Å; I25-K283 HydrophobicContact CD1-CB 3.81Å; I25-K283 HydrophobicContact CG1-CB 4.07Å; S279-K283 WeakPolarHBondContact O-CG 3.29Å; S279-K283 PolarHBondContact O-N 2.85Å; I280-K283 PolarHBondContact O-N 2.66Å; L281-K283 PolarHBondContact O-N 2.85Å
284I98.1Very high98.4Very high14 Ų1433.1 Ų33.17%0.07216%0.157CC..Hα-helixtrans-83.6-40.4-178.8-59.6163.3000111.5L24 I25 L32 I222 I280 L281L24-I284 HydrophobicContact CB-CD1 3.66Å; L24-I284 HydrophobicContact CB-CG1 4.03Å; L24-I284 HydrophobicContact CD1-CD1 4.1Å; L24-I284 HydrophobicContact CG-CD1 4.49Å; I25-I284 HydrophobicContact CG1-CG1 3.98Å; L32-I284 HydrophobicContact CD2-CD1 4.47Å; L32-I284 HydrophobicContact CD2-CG2 4.15Å; I222-I284 HydrophobicContact CD1-CD1 4.01Å; I280-I284 HydrophobicContact CG2-CD1 3.63Å; I280-I284 HydrophobicContact CG2-CG1 4.41Å; I280-I284 WeakPolarHBondContact O-CG1 3.32Å; I280-I284 PolarHBondContact O-N 3.45Å; I280-I284 VanDerWaalsContact O-N 3.15Å; L281-I284 PolarHBondContact O-N 2.97Å
285L96.8Very high98.4Very high52 Ų5236.1 Ų36.127%0.27217%0.172SC..  trans-111.10-170.1-53.3176000112.1A29 L32 K140 L141 H144 I146 L281A29-L285 HydrophobicContact CB-CD2 3.55Å; L32-L285 HydrophobicContact CD2-CD2 4.28Å; K140-L285 WeakPolarHBondContact CE-O 3.47Å; K140-L285 HydrophobicContact CG-CD1 4.14Å; K140-L285 PolarHBondContact NZ-O 3.42Å; L141-L285 HydrophobicContact CD2-CD1 4.44Å; H144-L285 HydrophobicContact CB-CD1 4.36Å; H144-L285 HydrophobicContact CB-CD2 4.14Å; I146-L285 HydrophobicContact CD1-CD2 3.81Å; I146-L285 HydrophobicContact CG1-CD1 4.03Å; I146-L285 HydrophobicContact CG1-CD2 4.13Å; L281-L285 HydrophobicContact CB-CD1 4.48Å; L281-L285 HydrophobicContact CD2-CD1 4.23Å; L281-L285 WeakPolarHBondContact O-CB 3.44Å; L281-L285 PolarHBondContact O-N 3.16Å

Retrieved 285 of 285 residues in 83.5 ms (Link to these results)