A0A090N8Q5_HUMAN Loading...

NEDD8 ultimate buster 1

AlphaFold DB , UniProt , Accession A0A090N8Q5, Species HUMAN (Homo sapiens, Human), Gene NYREN18, Length 601 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M57.3Low80.6Confident130 Ų13046.6 Ų46.664%0.6423%0.23SC*.  0-460-87.5-161.9-98.200113.6Q3 K4 K5 K94 E295M1-Q3 PolarHBondContact O-N 3.17Å; M1-K4 PolarHBondContact O-N 3.13Å; M1-K5 PolarHBondContact O-N 3.24Å; M1-K94 HydrophobicContact CE-CD 3.88Å; M1-K94 HydrophobicContact SD-CD 3.86Å; M1-K94 PolarHBondContact SD-NZ 3.49Å; M1-E295 WeakPolarHBondContact CE-OE2 3.46Å
2A71.9Confident81.3Confident15 Ų1545.8 Ų45.812%0.12423%0.23CC..Hα-helixtrans-57.4-40.6-176.900000114.4K5 Y6 Y351 Y590A2-K5 PolarHBondContact O-N 3.23Å; A2-Y6 WeakPolarHBondContact O-CB 3.49Å; A2-Y6 PolarHBondContact O-N 3.08Å; A2-Y351 HydrophobicContact CB-CE1 4.13Å; A2-Y590 HydrophobicContact CB-CE2 4.36Å
3Q77Confident81.9Confident124 Ų12447.2 Ų47.258%0.57924%0.235SC*.Hα-helixtrans-64.8-40.1178.1-67.7173.4-6.400113.6M1 Y6 L7M1-Q3 PolarHBondContact O-N 3.17Å; Q3-Y6 WeakPolarHBondContact O-CB 3.45Å; Q3-Y6 PolarHBondContact O-N 2.9Å; Q3-L7 WeakPolarHBondContact O-CB 3.23Å; Q3-L7 PolarHBondContact O-N 3.11Å
4K80.3Confident82.5Confident98 Ų9844.8 Ų44.843%0.42622%0.222SC..Hα-helixtrans-63.2-44.3176.3-177179.1-179.4176.50111.2M1 L7 Q8 E62M1-K4 PolarHBondContact O-N 3.13Å; K4-L7 PolarHBondContact O-N 2.94Å; K4-Q8 PolarHBondContact O-N 3.17Å; K4-E62 WeakPolarHBondContact CE-OE1 3.48Å; K4-E62 WeakPolarHBondContact CE-OE2 3.26Å; K4-E62 VanDerWaalsContact NZ-CD 3.26Å; K4-E62 IonicContact NZ-OE1 3.95Å; K4-E62 PolarHBondContact NZ-OE1 3.42Å; K4-E62 IonicContact NZ-OE2 2.68Å; K4-E62 PolarHBondContact NZ-OE2 3.41Å
5K78.5Confident83.1Confident33 Ų3342.5 Ų42.514%0.14321%0.211CC..Hα-helixtrans-63.8-46.4178.8-67.7-174.4172.6-160.70111.7M1 A2 L7 Q8 A9 E298M1-K5 PolarHBondContact O-N 3.24Å; A2-K5 PolarHBondContact O-N 3.23Å; K5-L7 VanDerWaalsContact C-N 3.32Å; K5-L7 PolarHBondContact O-N 2.74Å; K5-Q8 PolarHBondContact O-N 3.12Å; K5-A9 PolarHBondContact O-N 2.95Å; K5-E298 HydrophobicContact CD-CG 4.27Å; K5-E298 WeakPolarHBondContact CD-OE1 3.31Å; K5-E298 WeakPolarHBondContact CE-OE1 3.39Å; K5-E298 VanDerWaalsContact CE-OE2 3.24Å; K5-E298 WeakPolarHBondContact CE-OE2 3.37Å; K5-E298 VanDerWaalsContact CG-OE1 3.31Å; K5-E298 WeakPolarHBondContact CG-OE1 3.41Å; K5-E298 IonicContact NZ-OE1 3.7Å; K5-E298 PolarHBondContact NZ-OE1 2.77Å; K5-E298 IonicContact NZ-OE2 3.3Å; K5-E298 PolarHBondContact NZ-OE2 3.36Å
6Y83.9Confident83.6Confident3 Ų352 Ų521%0.01224%0.244CC..Hα-helixtrans-52.5-49.9171.3167-83.7000111.6A2 Q3 Q8 A9 K10 Y351 D356 R594A2-Y6 WeakPolarHBondContact O-CB 3.49Å; A2-Y6 PolarHBondContact O-N 3.08Å; Q3-Y6 WeakPolarHBondContact O-CB 3.45Å; Q3-Y6 PolarHBondContact O-N 2.9Å; Y6-Q8 PolarHBondContact O-N 3.48Å; Y6-A9 PolarHBondContact O-N 2.93Å; Y6-K10 HydrophobicContact CE1-CG 3.84Å; Y6-K10 HydrophobicContact CE2-CG 4.06Å; Y6-K10 PolarHBondContact O-N 3.37Å; Y6-K10 WeakPolarHBondContact OH-CE 3.32Å; Y6-K10 WeakPolarHBondContact OH-CG 3.29Å; Y6-Y351 HydrophobicContact CD2-CD2 4Å; Y6-Y351 HydrophobicContact CD2-CE1 4.38Å; Y6-Y351 AromaticContact CD2-CE2 3.77Å; Y6-Y351 HydrophobicContact CD2-CE2 3.77Å; Y6-Y351 HydrophobicContact CD2-CG 4.42Å; Y6-Y351 AromaticContact CD2-CZ 3.97Å; Y6-Y351 VanDerWaalsContact CD2-O 3.26Å; Y6-Y351 WeakPolarHBondContact CD2-O 3.44Å; Y6-Y351 HydrophobicContact CE2-CE2 4.33Å; Y6-Y351 HydrophobicContact CG-CE1 4.38Å; Y6-Y351 HydrophobicContact CG-CE2 4.22Å; Y6-Y351 AromaticContact CG-CZ 3.99Å; Y6-D356 WeakPolarHBondContact CE2-OD1 3.09Å; Y6-D356 PolarHBondContact OH-OD1 3.08Å; Y6-D356 VanDerWaalsContact OH-OD1 3.05Å; Y6-D356 PolarHBondContact OH-OD2 2.75Å; Y6-D356 VanDerWaalsContact OH-OD2 3.08Å; Y6-R594 VanDerWaalsContact CE1-CZ 3.44Å; Y6-R594 PolarHBondContact OH-NH1 2.83Å
7L85.9Confident84Confident15 Ų1554.2 Ų54.28%0.07925%0.254CS..Hα-helixtrans-62.3-43.9-178.9-178.258.3000111.2Q3 K4 K5 A9 K10 L11 L49 E55 V59Q3-L7 WeakPolarHBondContact O-CB 3.23Å; Q3-L7 PolarHBondContact O-N 3.11Å; K4-L7 PolarHBondContact O-N 2.94Å; K5-L7 VanDerWaalsContact C-N 3.32Å; K5-L7 PolarHBondContact O-N 2.74Å; L7-A9 VanDerWaalsContact C-N 3.33Å; L7-A9 PolarHBondContact O-N 3.09Å; L7-K10 PolarHBondContact O-N 3.23Å; L7-L11 HydrophobicContact CD1-CD1 4Å; L7-L11 HydrophobicContact CD1-CG 4.18Å; L7-L11 HydrophobicContact CG-CD1 3.9Å; L7-L11 WeakPolarHBondContact O-CB 3.48Å; L7-L11 VanDerWaalsContact O-CG 3.25Å; L7-L11 WeakPolarHBondContact O-CG 3.48Å; L7-L11 PolarHBondContact O-N 3.37Å; L7-L49 HydrophobicContact CD1-CD1 3.68Å; L7-E55 HydrophobicContact CD2-CB 4.41Å; L7-V59 HydrophobicContact CD2-CG2 3.95Å; L7-V59 HydrophobicContact CG-CG2 4.38Å
8Q87.1Confident84.4Confident44 Ų4454.9 Ų54.921%0.20626%0.26CS..Hα-helixtrans-59.8-41.9175.6-166.3-171.2-35.600112K4 K5 Y6 T12 V59 I63K4-Q8 PolarHBondContact O-N 3.17Å; K5-Q8 PolarHBondContact O-N 3.12Å; Y6-Q8 PolarHBondContact O-N 3.48Å; Q8-T12 WeakPolarHBondContact O-CB 3.49Å; Q8-T12 PolarHBondContact O-N 3.47Å; Q8-T12 PolarHBondContact O-OG1 2.81Å; Q8-V59 HydrophobicContact CB-CG1 3.83Å; Q8-V59 HydrophobicContact CG-CG1 4.05Å; Q8-I63 HydrophobicContact CG-CD1 3.97Å; Q8-I63 HydrophobicContact CG-CG1 3.81Å
9A86.1Confident84.7Confident25 Ų2564.1 Ų64.121%0.20729%0.292CS..Hα-helixtrans-65.8-45.9179.100000112.1K5 Y6 L7 T12 Q13 H352K5-A9 PolarHBondContact O-N 2.95Å; Y6-A9 PolarHBondContact O-N 2.93Å; L7-A9 VanDerWaalsContact C-N 3.33Å; L7-A9 PolarHBondContact O-N 3.09Å; A9-T12 WeakPolarHBondContact O-CB 3.33Å; A9-T12 PolarHBondContact O-N 3.42Å; A9-Q13 PolarHBondContact O-N 2.93Å; A9-H352 WeakPolarHBondContact CB-O 3.49Å
10K88.6Confident85Confident26 Ų2662.3 Ų62.311%0.11328%0.284CS..Hα-helixtrans-60.4-47.3175.7-81.9-61.5-156.9-1740113.1Y6 L7 T12 Q13 F14 L49 G354 D356Y6-K10 HydrophobicContact CE1-CG 3.84Å; Y6-K10 HydrophobicContact CE2-CG 4.06Å; Y6-K10 PolarHBondContact O-N 3.37Å; Y6-K10 WeakPolarHBondContact OH-CE 3.32Å; Y6-K10 WeakPolarHBondContact OH-CG 3.29Å; L7-K10 PolarHBondContact O-N 3.23Å; K10-T12 VanDerWaalsContact C-N 3.26Å; K10-T12 PolarHBondContact O-N 3.32Å; K10-Q13 WeakPolarHBondContact O-CA 3.45Å; K10-Q13 WeakPolarHBondContact O-CB 3.42Å; K10-Q13 PolarHBondContact O-N 3.41Å; K10-F14 PolarHBondContact O-N 3.17Å; K10-L49 HydrophobicContact CB-CD2 4.22Å; K10-L49 HydrophobicContact CG-CD2 4.45Å; K10-G354 VanDerWaalsContact CD-O 3.32Å; K10-G354 WeakPolarHBondContact CD-O 3.24Å; K10-G354 WeakPolarHBondContact CE-O 3.2Å; K10-G354 PolarHBondContact NZ-O 3Å; K10-D356 WeakPolarHBondContact CE-OD2 3.42Å; K10-D356 IonicContact NZ-OD2 3.36Å; K10-D356 PolarHBondContact NZ-OD2 2.75Å
11L90.1Very high85.2Confident0 Ų063 Ų630%029%0.288CS..Hα-helixtrans-61.9-39.2177.2-68.1169.4000110.9L7 Q13 F14 L15 Y45 L49 V56 V59 I60 I63L7-L11 HydrophobicContact CD1-CD1 4Å; L7-L11 HydrophobicContact CD1-CG 4.18Å; L7-L11 HydrophobicContact CG-CD1 3.9Å; L7-L11 WeakPolarHBondContact O-CB 3.48Å; L7-L11 VanDerWaalsContact O-CG 3.25Å; L7-L11 WeakPolarHBondContact O-CG 3.48Å; L7-L11 PolarHBondContact O-N 3.37Å; L11-Q13 VanDerWaalsContact C-N 3.31Å; L11-Q13 PolarHBondContact O-N 3.33Å; L11-F14 PolarHBondContact O-N 3.38Å; L11-L15 WeakPolarHBondContact O-CB 3.36Å; L11-L15 WeakPolarHBondContact O-CD1 3.31Å; L11-L15 WeakPolarHBondContact O-CG 3.44Å; L11-L15 PolarHBondContact O-N 3Å; L11-Y45 HydrophobicContact CD2-CD2 3.71Å; L11-Y45 HydrophobicContact CD2-CG 4.08Å; L11-L49 HydrophobicContact CD2-CD1 3.65Å; L11-L49 HydrophobicContact CG-CD1 4.12Å; L11-V56 HydrophobicContact CD1-CG1 4.17Å; L11-V56 HydrophobicContact CD2-CG1 3.75Å; L11-V59 HydrophobicContact CD1-CB 3.81Å; L11-V59 HydrophobicContact CD1-CG1 3.61Å; L11-I60 HydrophobicContact CD1-CG1 4.03Å; L11-I60 HydrophobicContact CD2-CD1 4.36Å; L11-I60 HydrophobicContact CD2-CG1 4.28Å; L11-I63 HydrophobicContact CB-CD1 3.97Å
12T89.2Confident86.7Confident37 Ų3757 Ų5723%0.22726%0.259CS..Hα-helixtrans-62.9-37.4173.5-550000112.1Q8 A9 K10 R16Q8-T12 WeakPolarHBondContact O-CB 3.49Å; Q8-T12 PolarHBondContact O-N 3.47Å; Q8-T12 PolarHBondContact O-OG1 2.81Å; A9-T12 WeakPolarHBondContact O-CB 3.33Å; A9-T12 PolarHBondContact O-N 3.42Å; K10-T12 VanDerWaalsContact C-N 3.26Å; K10-T12 PolarHBondContact O-N 3.32Å; T12-R16 VanDerWaalsContact O-CG 3.3Å; T12-R16 WeakPolarHBondContact O-CG 3.39Å; T12-R16 PolarHBondContact O-N 3.22Å; T12-R16 VanDerWaalsContact O-N 3.16Å
13Q88.8Confident87.4Confident63 Ų6362.5 Ų62.529%0.29428%0.276SS..Hα-helixtrans-64.6-47.9174.6-176.8-176.5-8.400111.4A9 K10 L11 L15 R16 E17A9-Q13 PolarHBondContact O-N 2.93Å; K10-Q13 WeakPolarHBondContact O-CA 3.45Å; K10-Q13 WeakPolarHBondContact O-CB 3.42Å; K10-Q13 PolarHBondContact O-N 3.41Å; L11-Q13 VanDerWaalsContact C-N 3.31Å; L11-Q13 PolarHBondContact O-N 3.33Å; Q13-L15 VanDerWaalsContact C-N 3.35Å; Q13-L15 PolarHBondContact O-N 2.9Å; Q13-R16 WeakPolarHBondContact O-CA 3.48Å; Q13-R16 WeakPolarHBondContact O-CB 3.18Å; Q13-R16 PolarHBondContact O-N 3.38Å; Q13-E17 HydrophobicContact CG-CG 4.5Å; Q13-E17 WeakPolarHBondContact CG-OE1 2.91Å; Q13-E17 PolarHBondContact NE2-OE1 3.12Å; Q13-E17 WeakPolarHBondContact O-CG 3.47Å; Q13-E17 PolarHBondContact O-N 3.44Å
14F90.5Very high87.9Confident14 Ų1461.7 Ų61.76%0.06127%0.271CS..Hα-helixtrans-61.3-43.2178.2-68-7.5000112.1K10 L11 R16 E17 D18 Y45 R48 L49K10-F14 PolarHBondContact O-N 3.17Å; L11-F14 PolarHBondContact O-N 3.38Å; F14-R16 PolarHBondContact O-N 3.45Å; F14-E17 PolarHBondContact O-N 3.2Å; F14-E17 VanDerWaalsContact O-N 3.15Å; F14-D18 WeakPolarHBondContact O-CB 2.88Å; F14-D18 PolarHBondContact O-N 3.22Å; F14-Y45 HydrophobicContact CB-CD1 4.2Å; F14-Y45 HydrophobicContact CB-CE1 3.74Å; F14-Y45 HydrophobicContact CB-CE2 4.13Å; F14-Y45 AromaticContact CD2-CD1 3.91Å; F14-Y45 HydrophobicContact CD2-CD1 3.91Å; F14-Y45 HydrophobicContact CD2-CE1 4.27Å; F14-Y45 HydrophobicContact CD2-CG 4.14Å; F14-Y45 HydrophobicContact CG-CE1 4.45Å; F14-Y45 PolarHBondContact O-OH 3.15Å; F14-R48 HydrophobicContact CE2-CB 4.1Å; F14-R48 HydrophobicContact CE2-CG 3.69Å; F14-R48 HydrophobicContact CZ-CG 3.87Å; F14-L49 HydrophobicContact CD2-CG 4.43Å; F14-L49 HydrophobicContact CE2-CD1 4.18Å; F14-L49 HydrophobicContact CE2-CD2 3.51Å; F14-L49 HydrophobicContact CE2-CG 3.59Å; F14-L49 HydrophobicContact CZ-CD2 3.66Å; F14-L49 HydrophobicContact CZ-CG 4.26Å
15L91.8Very high88.2Confident11 Ų1162 Ų626%0.05828%0.282CS..Hα-helixtrans-56.9-35.8173.2-69.8165.5000112.5L11 Q13 R19 I20 L22 L41 Y45 I63L11-L15 WeakPolarHBondContact O-CB 3.36Å; L11-L15 WeakPolarHBondContact O-CD1 3.31Å; L11-L15 WeakPolarHBondContact O-CG 3.44Å; L11-L15 PolarHBondContact O-N 3Å; Q13-L15 VanDerWaalsContact C-N 3.35Å; Q13-L15 PolarHBondContact O-N 2.9Å; L15-R19 CarbonylContact O-C 3.58Å; L15-R19 PolarHBondContact O-N 2.78Å; L15-R19 VanDerWaalsContact O-N 3.11Å; L15-I20 HydrophobicContact CD2-CB 3.84Å; L15-I20 HydrophobicContact CD2-CG2 3.64Å; L15-I20 PolarHBondContact O-N 3.48Å; L15-L22 HydrophobicContact CD1-CD1 3.61Å; L15-L22 HydrophobicContact CD1-CG 4.12Å; L15-L22 HydrophobicContact CD2-CD1 4.2Å; L15-L22 HydrophobicContact CD2-CD2 3.81Å; L15-L22 HydrophobicContact CD2-CG 3.9Å; L15-L41 HydrophobicContact CD2-CD2 3.89Å; L15-Y45 WeakPolarHBondContact CA-OH 3.46Å; L15-Y45 HydrophobicContact CD2-CE2 3.79Å; L15-Y45 HydrophobicContact CG-CE2 3.94Å; L15-Y45 PolarHBondContact N-OH 2.91Å; L15-I63 HydrophobicContact CD1-CD1 4.42Å; L15-I63 HydrophobicContact CD1-CG2 4.21Å
16R90.1Very high88.6Confident194 Ų19464.2 Ų64.273%0.73230%0.301SS*.Hα-helixtrans-73.3-43.2176-71.2171.1-176.6-177.52.7112.2T12 Q13 F14 D18 R19T12-R16 VanDerWaalsContact O-CG 3.3Å; T12-R16 WeakPolarHBondContact O-CG 3.39Å; T12-R16 PolarHBondContact O-N 3.22Å; T12-R16 VanDerWaalsContact O-N 3.16Å; Q13-R16 WeakPolarHBondContact O-CA 3.48Å; Q13-R16 WeakPolarHBondContact O-CB 3.18Å; Q13-R16 PolarHBondContact O-N 3.38Å; F14-R16 PolarHBondContact O-N 3.45Å; R16-D18 VanDerWaalsContact C-N 3.33Å; R16-R19 PolarHBondContact O-N 3.35Å
17E90.6Very high88.8Confident89 Ų8966.2 Ų66.242%0.41631%0.309SS..Hα-helixtrans-58.7-46.7176.5-72.2172.6-17100110.8Q13 F14 R19 R48Q13-E17 HydrophobicContact CG-CG 4.5Å; Q13-E17 WeakPolarHBondContact CG-OE1 2.91Å; Q13-E17 PolarHBondContact NE2-OE1 3.12Å; Q13-E17 WeakPolarHBondContact O-CG 3.47Å; Q13-E17 PolarHBondContact O-N 3.44Å; F14-E17 PolarHBondContact O-N 3.2Å; F14-E17 VanDerWaalsContact O-N 3.15Å; E17-R19 PolarHBondContact O-N 3.28Å; E17-R48 IonicContact OE2-CZ 3.94Å; E17-R48 IonicContact OE2-NH1 3.69Å; E17-R48 PolarHBondContact OE2-NH1 3.09Å; E17-R48 IonicContact OE2-NH2 2.78Å; E17-R48 PolarHBondContact OE2-NH2 3.42Å
18D90.8Very high88.8Confident67 Ų6765.9 Ų65.936%0.35831%0.307SS..THydrogen-bonded Turntrans-83.1-0.1-179-62.5-16.4000112.6F14 R16 I20 Y45F14-D18 WeakPolarHBondContact O-CB 2.88Å; F14-D18 PolarHBondContact O-N 3.22Å; R16-D18 VanDerWaalsContact C-N 3.33Å; D18-I20 HydrophobicContact CB-CD1 3.8Å; D18-I20 HydrophobicContact CB-CG1 3.93Å; D18-I20 PolarHBondContact O-N 2.87Å; D18-Y45 WeakPolarHBondContact OD2-CE1 3.32Å; D18-Y45 PolarHBondContact OD2-OH 3.22Å
19R90.6Very high88.7Confident229 Ų22966.7 Ų66.786%0.86431%0.313SS*.THydrogen-bonded Turntrans54.734.9-179.5-56.7-178.6-179.7179.60.2113.9L15 R16 E17L15-R19 CarbonylContact O-C 3.58Å; L15-R19 PolarHBondContact O-N 2.78Å; L15-R19 VanDerWaalsContact O-N 3.11Å; R16-R19 PolarHBondContact O-N 3.35Å; E17-R19 PolarHBondContact O-N 3.28Å
20I91.1Very high88.4Confident29 Ų2974.8 Ų74.815%0.14935%0.346CS..  trans-86.5131.1-177.6-66.4175.7000110.8L15 D18 L22 Y27 L41L15-I20 HydrophobicContact CD2-CB 3.84Å; L15-I20 HydrophobicContact CD2-CG2 3.64Å; L15-I20 PolarHBondContact O-N 3.48Å; D18-I20 HydrophobicContact CB-CD1 3.8Å; D18-I20 HydrophobicContact CB-CG1 3.93Å; D18-I20 PolarHBondContact O-N 2.87Å; I20-L22 HydrophobicContact CG2-CD2 4.09Å; I20-Y27 HydrophobicContact CG2-CD2 4.02Å; I20-Y27 HydrophobicContact CG2-CE1 4.39Å; I20-Y27 HydrophobicContact CG2-CE2 3.49Å; I20-Y27 VanDerWaalsContact CG2-CE2 3.49Å; I20-L41 HydrophobicContact CD1-CD1 3.55Å; I20-L41 HydrophobicContact CD1-CD2 4.24Å; I20-L41 HydrophobicContact CG2-CD2 4.18Å
21Q89.7Confident88Confident77 Ų7779.4 Ų79.436%0.3637%0.372SS..  trans-111.5100.4174.7-65.5-175.6-13.400109.4W23 K24Q21-W23 HydrophobicContact CB-CD2 4.17Å; Q21-W23 HydrophobicContact CB-CE3 4.32Å; Q21-W23 HydrophobicContact CB-CH2 3.99Å; Q21-W23 HydrophobicContact CB-CZ2 3.8Å; Q21-W23 HydrophobicContact CB-CZ3 4.23Å; Q21-W23 HydrophobicContact CG-CH2 3.77Å; Q21-W23 HydrophobicContact CG-CZ2 3.66Å; Q21-W23 HydrophobicContact CG-CZ3 4.43Å; Q21-W23 PolarHBondContact O-N 3.2Å; Q21-W23 VanDerWaalsContact O-N 3.14Å; Q21-K24 HydrophobicContact CB-CB 4.44Å; Q21-K24 HydrophobicContact CB-CD 4.25Å; Q21-K24 HydrophobicContact CB-CG 4.29Å; Q21-K24 PolarHBondContact O-N 3.26Å
22L88.6Confident87.5Confident4 Ų484.4 Ų84.42%0.02139%0.394CS..THydrogen-bonded Turntrans-61.9-24.2-173.9-68.4178.6000114L15 I20 K24 Y27 T28 L38 L41 I60 I63 R64L15-L22 HydrophobicContact CD1-CD1 3.61Å; L15-L22 HydrophobicContact CD1-CG 4.12Å; L15-L22 HydrophobicContact CD2-CD1 4.2Å; L15-L22 HydrophobicContact CD2-CD2 3.81Å; L15-L22 HydrophobicContact CD2-CG 3.9Å; I20-L22 HydrophobicContact CG2-CD2 4.09Å; L22-K24 PolarHBondContact O-N 2.82Å; L22-Y27 HydrophobicContact CD2-CD1 4.39Å; L22-Y27 HydrophobicContact CD2-CG 4.22Å; L22-Y27 WeakPolarHBondContact O-CB 2.99Å; L22-T28 PolarHBondContact O-OG1 3.28Å; L22-L38 HydrophobicContact CD2-CD1 3.79Å; L22-L41 HydrophobicContact CD2-CD2 3.8Å; L22-I60 HydrophobicContact CD1-CG2 4.02Å; L22-I60 HydrophobicContact CD2-CG2 4.16Å; L22-I63 HydrophobicContact CD1-CB 4.12Å; L22-I63 HydrophobicContact CD1-CG2 3.82Å; L22-R64 HydrophobicContact CB-CB 4.05Å; L22-R64 HydrophobicContact CB-CG 4.01Å; L22-R64 HydrophobicContact CD1-CB 4.16Å
23W87.1Confident87.3Confident131 Ų13189.1 Ų89.150%0.49641%0.411SS..THydrogen-bonded Turntrans-822.3178.662.491.4000113.8Q21 A67 I68Q21-W23 HydrophobicContact CB-CD2 4.17Å; Q21-W23 HydrophobicContact CB-CE3 4.32Å; Q21-W23 HydrophobicContact CB-CH2 3.99Å; Q21-W23 HydrophobicContact CB-CZ2 3.8Å; Q21-W23 HydrophobicContact CB-CZ3 4.23Å; Q21-W23 HydrophobicContact CG-CH2 3.77Å; Q21-W23 HydrophobicContact CG-CZ2 3.66Å; Q21-W23 HydrophobicContact CG-CZ3 4.43Å; Q21-W23 PolarHBondContact O-N 3.2Å; Q21-W23 VanDerWaalsContact O-N 3.14Å; W23-A67 HydrophobicContact CD2-CB 4.46Å; W23-A67 HydrophobicContact CE3-CB 3.68Å; W23-A67 HydrophobicContact CZ3-CB 4.32Å; W23-I68 HydrophobicContact CB-CG1 4.03Å
24K87.3Confident87.1Confident106 Ų10689.4 Ų89.446%0.46142%0.417SS..SBendtrans-111.1161.4176.4-70.3-171.4177169.80111.5Q21 L22 Y27 T28Q21-K24 HydrophobicContact CB-CB 4.44Å; Q21-K24 HydrophobicContact CB-CD 4.25Å; Q21-K24 HydrophobicContact CB-CG 4.29Å; Q21-K24 PolarHBondContact O-N 3.26Å; L22-K24 PolarHBondContact O-N 2.82Å; K24-Y27 PolarHBondContact O-N 2.93Å; K24-T28 PolarHBondContact O-N 3.48Å; K24-T28 VanDerWaalsContact O-N 3.14Å
25P85.2Confident86.6Confident104 Ų10489.3 Ų89.368%0.67542%0.42SS*.THydrogen-bonded Turntrans-57.5145.1167.7-23.234.2000111.1
26P88Confident86.1Confident81 Ų8196.2 Ų96.253%0.52646%0.456SS..THydrogen-bonded Turncis-8854.635.8-37.2000115A37P26-A37 HydrophobicContact CB-CB 3.87Å; P26-A37 HydrophobicContact CG-CB 3.72Å
27Y87.5Confident85.9Confident45 Ų4588.1 Ų88.118%0.17643%0.431CS..THydrogen-bonded Turntrans-84.4-27.2-172.9-52.3-71.9000113.6I20 L22 K24 G35 A37 L38 L41I20-Y27 HydrophobicContact CG2-CD2 4.02Å; I20-Y27 HydrophobicContact CG2-CE1 4.39Å; I20-Y27 HydrophobicContact CG2-CE2 3.49Å; I20-Y27 VanDerWaalsContact CG2-CE2 3.49Å; L22-Y27 HydrophobicContact CD2-CD1 4.39Å; L22-Y27 HydrophobicContact CD2-CG 4.22Å; L22-Y27 WeakPolarHBondContact O-CB 2.99Å; K24-Y27 PolarHBondContact O-N 2.93Å; Y27-G35 PolarHBondContact O-N 3.41Å; Y27-A37 HydrophobicContact CD1-CB 4.15Å; Y27-A37 HydrophobicContact CE1-CB 4.19Å; Y27-L38 HydrophobicContact CD1-CD1 4.38Å; Y27-L41 HydrophobicContact CD1-CD2 4.19Å; Y27-L41 HydrophobicContact CE1-CB 4.26Å; Y27-L41 HydrophobicContact CE1-CD2 3.81Å
28T86.9Confident85.8Confident7 Ų784 Ų844%0.04341%0.411CS..BIsolated β-bridgetrans-128.6131.8174.2-65.10000109.3L22 K24 K32 K33 R64 I68L22-T28 PolarHBondContact O-OG1 3.28Å; K24-T28 PolarHBondContact O-N 3.48Å; K24-T28 VanDerWaalsContact O-N 3.14Å; T28-K32 HydrophobicContact CG2-CB 4.47Å; T28-K33 WeakPolarHBondContact CA-O 3.32Å; T28-R64 WeakPolarHBondContact OG1-CD 3.37Å; T28-R64 PolarHBondContact OG1-NH1 2.94Å; T28-I68 HydrophobicContact CG2-CD1 3.71Å
29D84.2Confident85.6Confident62 Ų6286.1 Ų86.133%0.33242%0.418SS..  trans-80.8174.817678.6-1.1000112.5N31 K32 K33D29-N31 PolarHBondContact O-N 3.2Å; D29-N31 VanDerWaalsContact O-N 3.15Å; D29-N31 VanDerWaalsContact OD1-CA 3.26Å; D29-N31 WeakPolarHBondContact OD1-CA 3.25Å; D29-N31 WeakPolarHBondContact OD1-CB 3.43Å; D29-N31 PolarHBondContact OD1-N 3.12Å; D29-K32 PolarHBondContact O-N 3.29Å; D29-K32 PolarHBondContact OD1-N 3.32Å; D29-K33 PolarHBondContact N-O 3.03Å; D29-K33 VanDerWaalsContact N-O 3.11Å; D29-K33 WeakPolarHBondContact OD1-CA 3.22Å; D29-K33 WeakPolarHBondContact OD1-CB 3.4Å; D29-K33 PolarHBondContact OD1-N 3.45Å
30E79Confident85.5Confident195 Ų19580.9 Ų80.991%0.91141%0.406SS*.THydrogen-bonded Turntrans-60.3-23.4177.8-62.7-176.717200113.1K32E30-K32 VanDerWaalsContact C-N 3.33Å
31N80.8Confident85.5Confident122 Ų12279.7 Ų79.765%0.65240%0.401SS*.THydrogen-bonded Turntrans-90.810.9177.4-62.2-54.6000113.2D29 K33D29-N31 PolarHBondContact O-N 3.2Å; D29-N31 VanDerWaalsContact O-N 3.15Å; D29-N31 VanDerWaalsContact OD1-CA 3.26Å; D29-N31 WeakPolarHBondContact OD1-CA 3.25Å; D29-N31 WeakPolarHBondContact OD1-CB 3.43Å; D29-N31 PolarHBondContact OD1-N 3.12Å; N31-K33 HydrophobicContact CB-CD 4.39Å; N31-K33 HydrophobicContact CB-CG 4.2Å; N31-K33 PolarHBondContact O-N 2.93Å
32K80.5Confident85.5Confident105 Ų10576 Ų7646%0.45738%0.383SS..SBendtrans63.715.6-176.2-59.6175.9174.5-177.20114.7T28 D29 E30 R64 I68 T72T28-K32 HydrophobicContact CG2-CB 4.47Å; D29-K32 PolarHBondContact O-N 3.29Å; D29-K32 PolarHBondContact OD1-N 3.32Å; E30-K32 VanDerWaalsContact C-N 3.33Å; K32-R64 PolarHBondContact O-NH1 3.28Å; K32-I68 HydrophobicContact CB-CD1 4.49Å; K32-I68 HydrophobicContact CB-CG2 4.11Å; K32-I68 HydrophobicContact CD-CG2 3.76Å; K32-I68 HydrophobicContact CG-CG2 4.12Å; K32-T72 PolarHBondContact NZ-OG1 3.5Å
33K84.1Confident85.6Confident136 Ų13681.1 Ų81.159%0.59141%0.405SS*.PPolyproline II helixtrans-85.5166176.7-58.9-178.5177177.60111.9T28 D29 N31 G35 R64T28-K33 WeakPolarHBondContact CA-O 3.32Å; D29-K33 PolarHBondContact N-O 3.03Å; D29-K33 VanDerWaalsContact N-O 3.11Å; D29-K33 WeakPolarHBondContact OD1-CA 3.22Å; D29-K33 WeakPolarHBondContact OD1-CB 3.4Å; D29-K33 PolarHBondContact OD1-N 3.45Å; N31-K33 HydrophobicContact CB-CD 4.39Å; N31-K33 HydrophobicContact CB-CG 4.2Å; N31-K33 PolarHBondContact O-N 2.93Å; K33-G35 PolarHBondContact O-N 3.22Å; K33-R64 PolarHBondContact O-NH1 3.46Å
34V84.1Confident85.7Confident70 Ų7080 Ų8042%0.42441%0.406SS..BIsolated β-bridgetrans-63.1122.9179.2-176.40000110.3L38 E61V34-L38 HydrophobicContact CG1-CB 4.04Å; V34-L38 HydrophobicContact CG1-CD2 3.71Å; V34-E61 VanDerWaalsContact CG2-CD 3.45Å; V34-E61 WeakPolarHBondContact CG2-OE1 3.21Å; V34-E61 VanDerWaalsContact CG2-OE2 3.32Å; V34-E61 WeakPolarHBondContact CG2-OE2 3.39Å
35G81.3Confident85.9Confident11 Ų1175 Ų7511%0.11338%0.384CS..PPolyproline II helixtrans-81.5151170.500000112.3Y27 K33 A37 L38Y27-G35 PolarHBondContact O-N 3.41Å; K33-G35 PolarHBondContact O-N 3.22Å; G35-A37 PolarHBondContact O-N 3.1Å; G35-L38 VanDerWaalsContact O-CB 3.32Å; G35-L38 WeakPolarHBondContact O-CB 3.36Å; G35-L38 PolarHBondContact O-N 3.22Å; G35-L38 VanDerWaalsContact O-N 3.09Å
36L80.8Confident86.2Confident156 Ų15670.4 Ų70.482%0.81735%0.354SS*.THydrogen-bonded Turntrans-59.7-31.4-178.6-69.5168.6000113L38 K39L36-L38 PolarHBondContact O-N 3.3Å; L36-L38 VanDerWaalsContact O-N 3.12Å; L36-K39 PolarHBondContact O-N 2.82Å
37A86.3Confident86.2Confident24 Ų2472 Ų7220%0.19836%0.358CS..Hα-helixtrans-64.6-13.1178.300000114P26 Y27 G35 K39 L41P26-A37 HydrophobicContact CB-CB 3.87Å; P26-A37 HydrophobicContact CG-CB 3.72Å; Y27-A37 HydrophobicContact CD1-CB 4.15Å; Y27-A37 HydrophobicContact CE1-CB 4.19Å; G35-A37 PolarHBondContact O-N 3.1Å; A37-K39 VanDerWaalsContact C-N 3.33Å; A37-L41 PolarHBondContact O-N 2.75Å
38L87.7Confident86.1Confident2 Ų275.8 Ų75.81%0.0137%0.372CS..Hα-helixtrans-67.2-35.7176.9-158.579000111.9L22 Y27 V34 G35 L36 L41 A42 I60 E61L22-L38 HydrophobicContact CD2-CD1 3.79Å; Y27-L38 HydrophobicContact CD1-CD1 4.38Å; V34-L38 HydrophobicContact CG1-CB 4.04Å; V34-L38 HydrophobicContact CG1-CD2 3.71Å; G35-L38 VanDerWaalsContact O-CB 3.32Å; G35-L38 WeakPolarHBondContact O-CB 3.36Å; G35-L38 PolarHBondContact O-N 3.22Å; G35-L38 VanDerWaalsContact O-N 3.09Å; L36-L38 PolarHBondContact O-N 3.3Å; L36-L38 VanDerWaalsContact O-N 3.12Å; L38-L41 PolarHBondContact O-N 3.08Å; L38-A42 WeakPolarHBondContact O-CB 3.17Å; L38-A42 PolarHBondContact O-N 2.67Å; L38-I60 HydrophobicContact CD1-CG2 3.54Å; L38-I60 HydrophobicContact CD2-CG2 4.22Å; L38-I60 HydrophobicContact CG-CG2 3.84Å; L38-E61 HydrophobicContact CD2-CB 4.28Å; L38-E61 WeakPolarHBondContact CD2-OE2 3.5Å
39K86.6Confident86Confident113 Ų11376.1 Ų76.149%0.49137%0.374SS..Hα-helixtrans-68.9-43.9179.7-70.3-170.8173-168.60111.6L36 A37 L41 A42 K43 E57L36-K39 PolarHBondContact O-N 2.82Å; A37-K39 VanDerWaalsContact C-N 3.33Å; K39-L41 VanDerWaalsContact C-N 3.27Å; K39-L41 PolarHBondContact O-N 2.94Å; K39-A42 WeakPolarHBondContact O-CB 3.44Å; K39-A42 PolarHBondContact O-N 2.89Å; K39-A42 VanDerWaalsContact O-N 3.17Å; K39-K43 PolarHBondContact O-N 2.94Å; K39-E57 WeakPolarHBondContact CE-OE1 3.06Å
40D88.6Confident85.8Confident118 Ų11877 Ų7763%0.63138%0.376SS*.Hα-helixtrans-61.3-40.1176.4-60.5-33.2000111K43 Q44D40-K43 PolarHBondContact O-N 3.34Å; D40-Q44 PolarHBondContact O-N 3.39Å
41L90.5Very high85.9Confident5 Ų569.3 Ų69.33%0.02634%0.343CS..Hα-helixtrans-66.1-41.5174.8-173.466.4000112.3L15 I20 L22 Y27 A37 L38 K39 K43 Q44 Y45L15-L41 HydrophobicContact CD2-CD2 3.89Å; I20-L41 HydrophobicContact CD1-CD1 3.55Å; I20-L41 HydrophobicContact CD1-CD2 4.24Å; I20-L41 HydrophobicContact CG2-CD2 4.18Å; L22-L41 HydrophobicContact CD2-CD2 3.8Å; Y27-L41 HydrophobicContact CD1-CD2 4.19Å; Y27-L41 HydrophobicContact CE1-CB 4.26Å; Y27-L41 HydrophobicContact CE1-CD2 3.81Å; A37-L41 PolarHBondContact O-N 2.75Å; L38-L41 PolarHBondContact O-N 3.08Å; K39-L41 VanDerWaalsContact C-N 3.27Å; K39-L41 PolarHBondContact O-N 2.94Å; L41-K43 VanDerWaalsContact C-N 3.31Å; L41-K43 PolarHBondContact O-N 3.07Å; L41-Q44 PolarHBondContact O-N 2.95Å; L41-Y45 HydrophobicContact CD1-CD2 4.36Å; L41-Y45 HydrophobicContact CD1-CE1 4.02Å; L41-Y45 HydrophobicContact CD1-CE2 3.81Å; L41-Y45 HydrophobicContact CD2-CE2 4.13Å; L41-Y45 HydrophobicContact CG-CD2 4.16Å; L41-Y45 HydrophobicContact CG-CE2 3.83Å; L41-Y45 PolarHBondContact O-N 3.44Å
42A90.2Very high86.1Confident0 Ų066.4 Ų66.40%033%0.332CS..Hα-helixtrans-60.4-43.3176.300000111.2L38 K39 Y45 S46 V56 E57 I60L38-A42 WeakPolarHBondContact O-CB 3.17Å; L38-A42 PolarHBondContact O-N 2.67Å; K39-A42 WeakPolarHBondContact O-CB 3.44Å; K39-A42 PolarHBondContact O-N 2.89Å; K39-A42 VanDerWaalsContact O-N 3.17Å; A42-Y45 PolarHBondContact O-N 3.39Å; A42-S46 WeakPolarHBondContact O-CB 3.39Å; A42-S46 PolarHBondContact O-N 3.03Å; A42-V56 HydrophobicContact CB-CG1 4.18Å; A42-V56 WeakPolarHBondContact O-CG1 3.46Å; A42-E57 HydrophobicContact CB-CB 3.91Å; A42-E57 HydrophobicContact CB-CG 4.37Å; A42-I60 HydrophobicContact CB-CD1 4.04Å
43K90.1Very high86.4Confident110 Ų11065.2 Ų65.248%0.47833%0.328SS..Hα-helixtrans-61.4-48.5174.7-171.4176.2-178.61790112.2K39 D40 L41 Y45 S46 D47K39-K43 PolarHBondContact O-N 2.94Å; D40-K43 PolarHBondContact O-N 3.34Å; L41-K43 VanDerWaalsContact C-N 3.31Å; L41-K43 PolarHBondContact O-N 3.07Å; K43-Y45 VanDerWaalsContact C-N 3.31Å; K43-Y45 PolarHBondContact O-N 2.88Å; K43-S46 VanDerWaalsContact O-CB 3.32Å; K43-S46 WeakPolarHBondContact O-CB 3.49Å; K43-S46 PolarHBondContact O-N 3.16Å; K43-S46 VanDerWaalsContact O-N 3.12Å; K43-D47 PolarHBondContact O-N 3.14Å
44Q91.1Very high86.5Confident108 Ų10863.5 Ų63.551%0.50533%0.325SS..Hα-helixtrans-56.2-44.5177.5-176-173.7-0.500112.3D40 L41 R48D40-Q44 PolarHBondContact O-N 3.39Å; L41-Q44 PolarHBondContact O-N 2.95Å; Q44-R48 PolarHBondContact O-N 3.07Å
45Y91Very high86.6Confident0 Ų065.5 Ų65.50%033%0.33CS..Hα-helixtrans-75.7-29.7178.1-69.2-14.8000113.2L11 F14 L15 D18 L41 A42 K43 R48 L49 I60L11-Y45 HydrophobicContact CD2-CD2 3.71Å; L11-Y45 HydrophobicContact CD2-CG 4.08Å; F14-Y45 HydrophobicContact CB-CD1 4.2Å; F14-Y45 HydrophobicContact CB-CE1 3.74Å; F14-Y45 HydrophobicContact CB-CE2 4.13Å; F14-Y45 AromaticContact CD2-CD1 3.91Å; F14-Y45 HydrophobicContact CD2-CD1 3.91Å; F14-Y45 HydrophobicContact CD2-CE1 4.27Å; F14-Y45 HydrophobicContact CD2-CG 4.14Å; F14-Y45 HydrophobicContact CG-CE1 4.45Å; F14-Y45 PolarHBondContact O-OH 3.15Å; L15-Y45 WeakPolarHBondContact CA-OH 3.46Å; L15-Y45 HydrophobicContact CD2-CE2 3.79Å; L15-Y45 HydrophobicContact CG-CE2 3.94Å; L15-Y45 PolarHBondContact N-OH 2.91Å; D18-Y45 WeakPolarHBondContact OD2-CE1 3.32Å; D18-Y45 PolarHBondContact OD2-OH 3.22Å; L41-Y45 HydrophobicContact CD1-CD2 4.36Å; L41-Y45 HydrophobicContact CD1-CE1 4.02Å; L41-Y45 HydrophobicContact CD1-CE2 3.81Å; L41-Y45 HydrophobicContact CD2-CE2 4.13Å; L41-Y45 HydrophobicContact CG-CD2 4.16Å; L41-Y45 HydrophobicContact CG-CE2 3.83Å; L41-Y45 PolarHBondContact O-N 3.44Å; A42-Y45 PolarHBondContact O-N 3.39Å; K43-Y45 VanDerWaalsContact C-N 3.31Å; K43-Y45 PolarHBondContact O-N 2.88Å; Y45-R48 PolarHBondContact O-N 2.66Å; Y45-L49 VanDerWaalsContact O-CB 3.31Å; Y45-L49 WeakPolarHBondContact O-CB 3.39Å; Y45-L49 WeakPolarHBondContact O-CG 3.21Å; Y45-L49 PolarHBondContact O-N 3.11Å; Y45-I60 HydrophobicContact CD2-CD1 3.72Å; Y45-I60 HydrophobicContact CE2-CD1 4.41Å
46S90.3Very high86.9Confident8 Ų865 Ų656%0.05632%0.324CS..Hα-helixtrans-60.9-45.9172.1-164.70000111.2A42 K43 L49 E50 C51 E53A42-S46 WeakPolarHBondContact O-CB 3.39Å; A42-S46 PolarHBondContact O-N 3.03Å; K43-S46 VanDerWaalsContact O-CB 3.32Å; K43-S46 WeakPolarHBondContact O-CB 3.49Å; K43-S46 PolarHBondContact O-N 3.16Å; K43-S46 VanDerWaalsContact O-N 3.12Å; S46-L49 PolarHBondContact O-N 3.14Å; S46-E50 WeakPolarHBondContact O-CA 3.27Å; S46-E50 PolarHBondContact O-N 2.66Å; S46-C51 PolarHBondContact O-N 3.44Å; S46-C51 PolarHBondContact OG-O 2.83Å; S46-E53 VanDerWaalsContact OG-CA 3.24Å; S46-E53 WeakPolarHBondContact OG-CA 3.41Å; S46-E53 PolarHBondContact OG-N 3.11Å; S46-E53 VanDerWaalsContact OG-N 3.09Å
47D87.9Confident87.3Confident114 Ų11459.9 Ų59.961%0.6130%0.297SS*.Hα-helixtrans-63.9-41.7177-66.2-22.9000110.8K43 L49K43-D47 PolarHBondContact O-N 3.14Å; D47-L49 PolarHBondContact O-N 3.06Å
48R87.1Confident87.4Confident125 Ų12565.5 Ų65.547%0.47232%0.317SS..Hα-helixtrans-69.6-29.6178.8-170.1173.2176.4-165.8-7.2113.8F14 E17 Q44 Y45F14-R48 HydrophobicContact CE2-CB 4.1Å; F14-R48 HydrophobicContact CE2-CG 3.69Å; F14-R48 HydrophobicContact CZ-CG 3.87Å; E17-R48 IonicContact OE2-CZ 3.94Å; E17-R48 IonicContact OE2-NH1 3.69Å; E17-R48 PolarHBondContact OE2-NH1 3.09Å; E17-R48 IonicContact OE2-NH2 2.78Å; E17-R48 PolarHBondContact OE2-NH2 3.42Å; Q44-R48 PolarHBondContact O-N 3.07Å; Y45-R48 PolarHBondContact O-N 2.66Å
49L83Confident87.4Confident14 Ų1465.8 Ų65.87%0.07332%0.318CS..Hα-helixtrans-98.7-5.2-178.5-70.8174.2000114L7 K10 L11 F14 Y45 S46 D47 C51L7-L49 HydrophobicContact CD1-CD1 3.68Å; K10-L49 HydrophobicContact CB-CD2 4.22Å; K10-L49 HydrophobicContact CG-CD2 4.45Å; L11-L49 HydrophobicContact CD2-CD1 3.65Å; L11-L49 HydrophobicContact CG-CD1 4.12Å; F14-L49 HydrophobicContact CD2-CG 4.43Å; F14-L49 HydrophobicContact CE2-CD1 4.18Å; F14-L49 HydrophobicContact CE2-CD2 3.51Å; F14-L49 HydrophobicContact CE2-CG 3.59Å; F14-L49 HydrophobicContact CZ-CD2 3.66Å; F14-L49 HydrophobicContact CZ-CG 4.26Å; Y45-L49 VanDerWaalsContact O-CB 3.31Å; Y45-L49 WeakPolarHBondContact O-CB 3.39Å; Y45-L49 WeakPolarHBondContact O-CG 3.21Å; Y45-L49 PolarHBondContact O-N 3.11Å; S46-L49 PolarHBondContact O-N 3.14Å; D47-L49 PolarHBondContact O-N 3.06Å; L49-C51 VanDerWaalsContact C-N 3.32Å; L49-C51 HydrophobicContact CB-CB 4.47Å; L49-C51 WeakPolarHBondContact CB-SG 3.23Å; L49-C51 PolarHBondContact O-N 3.07Å
50E81.2Confident87.6Confident82 Ų8260.4 Ų60.438%0.38330%0.295SS..THydrogen-bonded Turntrans5050.4-173.4-58.9177.9171.200112.1S46 T598S46-E50 WeakPolarHBondContact O-CA 3.27Å; S46-E50 PolarHBondContact O-N 2.66Å; E50-T598 VanDerWaalsContact OE2-CA 3.23Å; E50-T598 WeakPolarHBondContact OE2-CA 3.41Å; E50-T598 PolarHBondContact OE2-N 3.29Å; E50-T598 VanDerWaalsContact OE2-N 3.11Å
51C80.8Confident87.6Confident32 Ų3257 Ų5722%0.21628%0.275CS..SBendtrans-129.9-179.8-178.262.40000111.9S46 L49 V56S46-C51 PolarHBondContact O-N 3.44Å; S46-C51 PolarHBondContact OG-O 2.83Å; L49-C51 VanDerWaalsContact C-N 3.32Å; L49-C51 HydrophobicContact CB-CB 4.47Å; L49-C51 WeakPolarHBondContact CB-SG 3.23Å; L49-C51 PolarHBondContact O-N 3.07Å; C51-V56 WeakPolarHBondContact SG-CG2 3.47Å
52C85Confident87.5Confident61 Ų6159.6 Ų59.641%0.41229%0.287SS..  trans-75.4125.1-177.4-177.30000110.7N54 E55 V56C52-N54 PolarHBondContact O-N 3.16Å; C52-E55 HydrophobicContact CB-CB 4.23Å; C52-E55 HydrophobicContact CB-CG 3.93Å; C52-E55 WeakPolarHBondContact O-CB 3.33Å; C52-E55 PolarHBondContact O-N 3.41Å; C52-V56 PolarHBondContact O-N 3.47Å; C52-V56 VanDerWaalsContact O-N 3.1Å
53E86.6Confident87.4Confident80 Ų8060.7 Ų60.737%0.37429%0.293SS..Hα-helixtrans-54.2-41.9-180-175-179.3168.900111.6S46 E55 V56 E57S46-E53 VanDerWaalsContact OG-CA 3.24Å; S46-E53 WeakPolarHBondContact OG-CA 3.41Å; S46-E53 PolarHBondContact OG-N 3.11Å; S46-E53 VanDerWaalsContact OG-N 3.09Å; E53-E55 VanDerWaalsContact C-N 3.27Å; E53-E55 PolarHBondContact O-N 3.02Å; E53-V56 PolarHBondContact O-N 3.27Å; E53-E57 WeakPolarHBondContact O-CB 3.31Å; E53-E57 PolarHBondContact O-N 2.83Å
54N85.7Confident87.4Confident101 Ų10156 Ų5654%0.5427%0.272SS..Hα-helixtrans-62.8-31.6178.3-67.2-30000113.2C52 K58C52-N54 PolarHBondContact O-N 3.16Å; N54-K58 WeakPolarHBondContact O-CD 3.35Å; N54-K58 WeakPolarHBondContact O-CG 3.47Å; N54-K58 PolarHBondContact O-N 3.18Å
55E86.1Confident87.2Confident111 Ų11153 Ų5352%0.51926%0.262SS..Hα-helixtrans-76.5-41.3176.8-67.1-175.116200110.8L7 C52 E53 K58 V59L7-E55 HydrophobicContact CD2-CB 4.41Å; C52-E55 HydrophobicContact CB-CB 4.23Å; C52-E55 HydrophobicContact CB-CG 3.93Å; C52-E55 WeakPolarHBondContact O-CB 3.33Å; C52-E55 PolarHBondContact O-N 3.41Å; E53-E55 VanDerWaalsContact C-N 3.27Å; E53-E55 PolarHBondContact O-N 3.02Å; E55-K58 PolarHBondContact O-N 3.31Å; E55-V59 WeakPolarHBondContact O-CG2 3Å; E55-V59 PolarHBondContact O-N 2.8Å
56V88Confident86.9Confident0 Ų056.6 Ų56.60%028%0.278CS..Hα-helixtrans-63.2-46.6175.7178.10000111.1L11 A42 C51 C52 E53 K58 V59 I60L11-V56 HydrophobicContact CD1-CG1 4.17Å; L11-V56 HydrophobicContact CD2-CG1 3.75Å; A42-V56 HydrophobicContact CB-CG1 4.18Å; A42-V56 WeakPolarHBondContact O-CG1 3.46Å; C51-V56 WeakPolarHBondContact SG-CG2 3.47Å; C52-V56 PolarHBondContact O-N 3.47Å; C52-V56 VanDerWaalsContact O-N 3.1Å; E53-V56 PolarHBondContact O-N 3.27Å; V56-K58 VanDerWaalsContact C-N 3.33Å; V56-K58 PolarHBondContact O-N 2.96Å; V56-V59 PolarHBondContact O-N 2.93Å; V56-I60 HydrophobicContact CG1-CD1 3.57Å; V56-I60 HydrophobicContact CG1-CG1 4.03Å; V56-I60 WeakPolarHBondContact O-CB 3.49Å; V56-I60 WeakPolarHBondContact O-CG1 3.21Å; V56-I60 PolarHBondContact O-N 3.35Å
57E88.7Confident86.7Confident50 Ų5057.4 Ų57.423%0.23429%0.285CS..Hα-helixtrans-56.9-48178.6-173-178.3-179.800110.7K39 A42 E53 V59 I60 E61K39-E57 WeakPolarHBondContact CE-OE1 3.06Å; A42-E57 HydrophobicContact CB-CB 3.91Å; A42-E57 HydrophobicContact CB-CG 4.37Å; E53-E57 WeakPolarHBondContact O-CB 3.31Å; E53-E57 PolarHBondContact O-N 2.83Å; E57-V59 PolarHBondContact O-N 3.05Å; E57-I60 PolarHBondContact O-N 3.48Å; E57-E61 VanDerWaalsContact O-CB 3.25Å; E57-E61 WeakPolarHBondContact O-CB 3.3Å; E57-E61 PolarHBondContact O-N 2.97Å
58K88.6Confident86.6Confident142 Ų14253 Ų5362%0.61726%0.261SS*.Hα-helixtrans-58.7-45.9176.5-74.5172.7-174.3178.90112.2N54 E55 V56 E61 E62N54-K58 WeakPolarHBondContact O-CD 3.35Å; N54-K58 WeakPolarHBondContact O-CG 3.47Å; N54-K58 PolarHBondContact O-N 3.18Å; E55-K58 PolarHBondContact O-N 3.31Å; V56-K58 VanDerWaalsContact C-N 3.33Å; V56-K58 PolarHBondContact O-N 2.96Å; K58-E61 PolarHBondContact O-N 3.44Å; K58-E62 WeakPolarHBondContact O-CG 3.42Å; K58-E62 PolarHBondContact O-N 3.27Å
59V88.4Confident86.4Confident7 Ų750.1 Ų50.14%0.04225%0.253CS..Hα-helixtrans-72.1-39.6-177.4177.60000111.8L7 Q8 L11 E55 V56 E57 E61 E62 I63L7-V59 HydrophobicContact CD2-CG2 3.95Å; L7-V59 HydrophobicContact CG-CG2 4.38Å; Q8-V59 HydrophobicContact CB-CG1 3.83Å; Q8-V59 HydrophobicContact CG-CG1 4.05Å; L11-V59 HydrophobicContact CD1-CB 3.81Å; L11-V59 HydrophobicContact CD1-CG1 3.61Å; E55-V59 WeakPolarHBondContact O-CG2 3Å; E55-V59 PolarHBondContact O-N 2.8Å; V56-V59 PolarHBondContact O-N 2.93Å; E57-V59 PolarHBondContact O-N 3.05Å; V59-E61 VanDerWaalsContact C-N 3.28Å; V59-E61 PolarHBondContact O-N 2.96Å; V59-E62 WeakPolarHBondContact O-CB 3.14Å; V59-E62 PolarHBondContact O-N 3.06Å; V59-I63 HydrophobicContact CG1-CD1 4.21Å; V59-I63 VanDerWaalsContact O-CG1 3.27Å; V59-I63 WeakPolarHBondContact O-CG1 3.46Å; V59-I63 PolarHBondContact O-N 3.47Å
60I89.9Confident86.4Confident0 Ų055.1 Ų55.10%027%0.271CS..Hα-helixtrans-61.1-41.8173.3-70.5179000110.3L11 L22 L38 A42 Y45 V56 E57 I63 R64L11-I60 HydrophobicContact CD1-CG1 4.03Å; L11-I60 HydrophobicContact CD2-CD1 4.36Å; L11-I60 HydrophobicContact CD2-CG1 4.28Å; L22-I60 HydrophobicContact CD1-CG2 4.02Å; L22-I60 HydrophobicContact CD2-CG2 4.16Å; L38-I60 HydrophobicContact CD1-CG2 3.54Å; L38-I60 HydrophobicContact CD2-CG2 4.22Å; L38-I60 HydrophobicContact CG-CG2 3.84Å; A42-I60 HydrophobicContact CB-CD1 4.04Å; Y45-I60 HydrophobicContact CD2-CD1 3.72Å; Y45-I60 HydrophobicContact CE2-CD1 4.41Å; V56-I60 HydrophobicContact CG1-CD1 3.57Å; V56-I60 HydrophobicContact CG1-CG1 4.03Å; V56-I60 WeakPolarHBondContact O-CB 3.49Å; V56-I60 WeakPolarHBondContact O-CG1 3.21Å; V56-I60 PolarHBondContact O-N 3.35Å; E57-I60 PolarHBondContact O-N 3.48Å; I60-I63 PolarHBondContact O-N 2.92Å; I60-R64 WeakPolarHBondContact O-CB 3.34Å; I60-R64 PolarHBondContact O-N 3.27Å
61E89.1Confident86.5Confident46 Ų4652.6 Ų52.622%0.21527%0.268CS..Hα-helixtrans-64-41.1176.8178.855.8-164.800112V34 L38 E57 K58 V59 I63 R64 C65V34-E61 VanDerWaalsContact CG2-CD 3.45Å; V34-E61 WeakPolarHBondContact CG2-OE1 3.21Å; V34-E61 VanDerWaalsContact CG2-OE2 3.32Å; V34-E61 WeakPolarHBondContact CG2-OE2 3.39Å; L38-E61 HydrophobicContact CD2-CB 4.28Å; L38-E61 WeakPolarHBondContact CD2-OE2 3.5Å; E57-E61 VanDerWaalsContact O-CB 3.25Å; E57-E61 WeakPolarHBondContact O-CB 3.3Å; E57-E61 PolarHBondContact O-N 2.97Å; K58-E61 PolarHBondContact O-N 3.44Å; V59-E61 VanDerWaalsContact C-N 3.28Å; V59-E61 PolarHBondContact O-N 2.96Å; E61-I63 VanDerWaalsContact C-N 3.35Å; E61-I63 PolarHBondContact O-N 3.39Å; E61-R64 PolarHBondContact O-N 3.01Å; E61-R64 IonicContact OE1-CZ 3.84Å; E61-R64 IonicContact OE1-NE 2.75Å; E61-R64 PolarHBondContact OE1-NE 3.19Å; E61-R64 IonicContact OE1-NH2 2.73Å; E61-R64 PolarHBondContact OE1-NH2 2.97Å; E61-R64 IonicContact OE2-CZ 2.72Å; E61-R64 IonicContact OE2-NE 3.48Å; E61-R64 PolarHBondContact OE2-NE 3.44Å; E61-R64 IonicContact OE2-NH2 3.16Å; E61-R64 PolarHBondContact OE2-NH2 2.99Å; E61-C65 WeakPolarHBondContact O-CB 3.42Å; E61-C65 PolarHBondContact O-N 3.39Å; E61-C65 PolarHBondContact O-SG 2.86Å; E61-C65 PolarHBondContact OE1-SG 3.15Å
62E87.8Confident86.7Confident61 Ų6153 Ų5329%0.28527%0.269SS..Hα-helixtrans-59.9-42.2171.5-74.8178.3-165.300112K4 K58 V59 K66K4-E62 WeakPolarHBondContact CE-OE1 3.48Å; K4-E62 WeakPolarHBondContact CE-OE2 3.26Å; K4-E62 VanDerWaalsContact NZ-CD 3.26Å; K4-E62 IonicContact NZ-OE1 3.95Å; K4-E62 PolarHBondContact NZ-OE1 3.42Å; K4-E62 IonicContact NZ-OE2 2.68Å; K4-E62 PolarHBondContact NZ-OE2 3.41Å; K58-E62 WeakPolarHBondContact O-CG 3.42Å; K58-E62 PolarHBondContact O-N 3.27Å; V59-E62 WeakPolarHBondContact O-CB 3.14Å; V59-E62 PolarHBondContact O-N 3.06Å; E62-K66 WeakPolarHBondContact O-CB 3.17Å; E62-K66 VanDerWaalsContact O-CG 3.29Å; E62-K66 WeakPolarHBondContact O-CG 3.43Å; E62-K66 PolarHBondContact O-N 3.41Å
63I88.4Confident86.5Confident23 Ų2350.4 Ų50.412%0.11825%0.253CS..Hα-helixtrans-63.8-44.4176.5-64.2164.8000110.3Q8 L11 L15 L22 V59 I60 E61 K66 A67Q8-I63 HydrophobicContact CG-CD1 3.97Å; Q8-I63 HydrophobicContact CG-CG1 3.81Å; L11-I63 HydrophobicContact CB-CD1 3.97Å; L15-I63 HydrophobicContact CD1-CD1 4.42Å; L15-I63 HydrophobicContact CD1-CG2 4.21Å; L22-I63 HydrophobicContact CD1-CB 4.12Å; L22-I63 HydrophobicContact CD1-CG2 3.82Å; V59-I63 HydrophobicContact CG1-CD1 4.21Å; V59-I63 VanDerWaalsContact O-CG1 3.27Å; V59-I63 WeakPolarHBondContact O-CG1 3.46Å; V59-I63 PolarHBondContact O-N 3.47Å; I60-I63 PolarHBondContact O-N 2.92Å; E61-I63 VanDerWaalsContact C-N 3.35Å; E61-I63 PolarHBondContact O-N 3.39Å; I63-K66 PolarHBondContact O-N 2.82Å; I63-A67 WeakPolarHBondContact O-CB 3.39Å; I63-A67 PolarHBondContact O-N 2.95Å
64R90.8Very high86.4Confident10 Ų1049.8 Ų49.84%0.03825%0.252CS..Hα-helixtrans-60.5-49.8177.6-173.3-172.276.478.110.5111L22 T28 K32 K33 I60 E61 K66 A67 I68L22-R64 HydrophobicContact CB-CB 4.05Å; L22-R64 HydrophobicContact CB-CG 4.01Å; L22-R64 HydrophobicContact CD1-CB 4.16Å; T28-R64 WeakPolarHBondContact OG1-CD 3.37Å; T28-R64 PolarHBondContact OG1-NH1 2.94Å; K32-R64 PolarHBondContact O-NH1 3.28Å; K33-R64 PolarHBondContact O-NH1 3.46Å; I60-R64 WeakPolarHBondContact O-CB 3.34Å; I60-R64 PolarHBondContact O-N 3.27Å; E61-R64 PolarHBondContact O-N 3.01Å; E61-R64 IonicContact OE1-CZ 3.84Å; E61-R64 IonicContact OE1-NE 2.75Å; E61-R64 PolarHBondContact OE1-NE 3.19Å; E61-R64 IonicContact OE1-NH2 2.73Å; E61-R64 PolarHBondContact OE1-NH2 2.97Å; E61-R64 IonicContact OE2-CZ 2.72Å; E61-R64 IonicContact OE2-NE 3.48Å; E61-R64 PolarHBondContact OE2-NE 3.44Å; E61-R64 IonicContact OE2-NH2 3.16Å; E61-R64 PolarHBondContact OE2-NH2 2.99Å; R64-K66 PolarHBondContact O-N 3.43Å; R64-A67 PolarHBondContact O-N 3.41Å; R64-A67 VanDerWaalsContact O-N 3.16Å; R64-I68 HydrophobicContact CG-CD1 3.98Å; R64-I68 WeakPolarHBondContact O-CG1 3.5Å; R64-I68 PolarHBondContact O-N 2.92Å
65C86.6Confident86.3Confident45 Ų4549.3 Ų49.330%0.30425%0.249SC..Hα-helixtrans-57.3-48.7178.1-73.10000111.3E61 A67 I68 E69E61-C65 WeakPolarHBondContact O-CB 3.42Å; E61-C65 PolarHBondContact O-N 3.39Å; E61-C65 PolarHBondContact O-SG 2.86Å; E61-C65 PolarHBondContact OE1-SG 3.15Å; C65-A67 VanDerWaalsContact C-N 3.31Å; C65-A67 PolarHBondContact O-N 3.41Å; C65-I68 PolarHBondContact O-N 2.77Å; C65-E69 WeakPolarHBondContact O-CB 3.25Å; C65-E69 WeakPolarHBondContact O-CG 3.33Å; C65-E69 PolarHBondContact O-N 2.91Å
66K85.1Confident86.2Confident77 Ų7747.4 Ų47.434%0.33524%0.242SC..Hα-helixtrans-59.7-39.5176.6-74.3176.4-177.2177.90112.6E62 I63 R64 R70E62-K66 WeakPolarHBondContact O-CB 3.17Å; E62-K66 VanDerWaalsContact O-CG 3.29Å; E62-K66 WeakPolarHBondContact O-CG 3.43Å; E62-K66 PolarHBondContact O-N 3.41Å; I63-K66 PolarHBondContact O-N 2.82Å; R64-K66 PolarHBondContact O-N 3.43Å; K66-R70 WeakPolarHBondContact O-CB 3.43Å; K66-R70 WeakPolarHBondContact O-CG 3.15Å; K66-R70 PolarHBondContact O-N 3.19Å
67A86.2Confident86.2Confident24 Ų2451.4 Ų51.420%0.19826%0.258CS..Hα-helixtrans-66.7-41.1178.300000112.4W23 I63 R64 C65 G71W23-A67 HydrophobicContact CD2-CB 4.46Å; W23-A67 HydrophobicContact CE3-CB 3.68Å; W23-A67 HydrophobicContact CZ3-CB 4.32Å; I63-A67 WeakPolarHBondContact O-CB 3.39Å; I63-A67 PolarHBondContact O-N 2.95Å; R64-A67 PolarHBondContact O-N 3.41Å; R64-A67 VanDerWaalsContact O-N 3.16Å; C65-A67 VanDerWaalsContact C-N 3.31Å; C65-A67 PolarHBondContact O-N 3.41Å; A67-G71 PolarHBondContact O-N 2.87Å
68I85.9Confident86.1Confident22 Ų2259 Ų5911%0.11329%0.285CS..Hα-helixtrans-67.9-42.4176.8-67.7169000111.2W23 T28 K32 R64 C65 G71 T72W23-I68 HydrophobicContact CB-CG1 4.03Å; T28-I68 HydrophobicContact CG2-CD1 3.71Å; K32-I68 HydrophobicContact CB-CD1 4.49Å; K32-I68 HydrophobicContact CB-CG2 4.11Å; K32-I68 HydrophobicContact CD-CG2 3.76Å; K32-I68 HydrophobicContact CG-CG2 4.12Å; R64-I68 HydrophobicContact CG-CD1 3.98Å; R64-I68 WeakPolarHBondContact O-CG1 3.5Å; R64-I68 PolarHBondContact O-N 2.92Å; C65-I68 PolarHBondContact O-N 2.77Å; I68-G71 PolarHBondContact O-N 3.29Å; I68-T72 WeakPolarHBondContact O-CB 3.27Å; I68-T72 PolarHBondContact O-N 3.28Å; I68-T72 PolarHBondContact O-OG1 3.47Å
69E82.6Confident86Confident64 Ų6457.5 Ų57.530%0.29929%0.288SS..Hα-helixtrans-61-45.9175.9-74.7-178159.900110.9C65 G71 T72 G73 K98C65-E69 WeakPolarHBondContact O-CB 3.25Å; C65-E69 WeakPolarHBondContact O-CG 3.33Å; C65-E69 PolarHBondContact O-N 2.91Å; E69-G71 PolarHBondContact O-N 3.46Å; E69-T72 PolarHBondContact O-N 2.74Å; E69-G73 PolarHBondContact O-N 3.28Å; E69-K98 WeakPolarHBondContact OE1-CE 3.27Å; E69-K98 IonicContact OE1-NZ 3.49Å; E69-K98 PolarHBondContact OE1-NZ 2.97Å
70R83.2Confident85.8Confident119 Ų11961.1 Ų61.145%0.44931%0.31SS..Hα-helixtrans-62.1-41.7174.4-77-179.8176.5179.6-0.3112.9K66 G73 N74 E86K66-R70 WeakPolarHBondContact O-CB 3.43Å; K66-R70 WeakPolarHBondContact O-CG 3.15Å; K66-R70 PolarHBondContact O-N 3.19Å; R70-G73 PolarHBondContact O-N 3.24Å; R70-N74 PolarHBondContact O-N 3Å; R70-N74 PolarHBondContact O-ND2 2.72Å; R70-E86 IonicContact NH2-OE2 2.78Å; R70-E86 PolarHBondContact NH2-OE2 2.97Å
71G83.7Confident85.5Confident30 Ų3063 Ų6331%0.30933%0.329SS..Hα-helixtrans-60.5-47.8175.100000111.9A67 I68 E69 G73 N74 D75A67-G71 PolarHBondContact O-N 2.87Å; I68-G71 PolarHBondContact O-N 3.29Å; E69-G71 PolarHBondContact O-N 3.46Å; G71-G73 VanDerWaalsContact C-N 3.35Å; G71-G73 PolarHBondContact O-N 2.67Å; G71-N74 WeakPolarHBondContact O-CB 3.32Å; G71-N74 PolarHBondContact O-N 3.2Å; G71-D75 PolarHBondContact O-N 2.94Å; G71-D75 VanDerWaalsContact O-N 3.14Å
72T83.5Confident85.4Confident41 Ų4163.5 Ų63.525%0.25233%0.333SS..Hα-helixtrans-64.2-39.6178.3-49.90000111.5K32 I68 E69 D75 N76K32-T72 PolarHBondContact NZ-OG1 3.5Å; I68-T72 WeakPolarHBondContact O-CB 3.27Å; I68-T72 PolarHBondContact O-N 3.28Å; I68-T72 PolarHBondContact O-OG1 3.47Å; E69-T72 PolarHBondContact O-N 2.74Å; T72-D75 PolarHBondContact O-N 2.89Å; T72-N76 WeakPolarHBondContact O-CB 3.2Å; T72-N76 PolarHBondContact O-N 2.64Å
73G82Confident85.4Confident6 Ų660.6 Ų60.66%0.06232%0.319CS..Hα-helixtrans-61.6-41.317400000112.9E69 R70 G71 D75 N76 Y77 H149E69-G73 PolarHBondContact O-N 3.28Å; R70-G73 PolarHBondContact O-N 3.24Å; G71-G73 VanDerWaalsContact C-N 3.35Å; G71-G73 PolarHBondContact O-N 2.67Å; G73-D75 PolarHBondContact O-N 2.98Å; G73-N76 PolarHBondContact O-N 2.87Å; G73-Y77 WeakPolarHBondContact O-CB 3.41Å; G73-Y77 PolarHBondContact O-N 3.27Å; G73-H149 PolarHBondContact O-CE1 2.87Å; G73-H149 VanDerWaalsContact O-CE1 3.25Å; G73-H149 PolarHBondContact O-NE2 3.47Å
74N84.6Confident85.3Confident66 Ų6660 Ų6035%0.35332%0.316SS..Hα-helixtrans-63.2-42.4176.5-71.4-30.2000112R70 G71 Y77 R78 H149 N150R70-N74 PolarHBondContact O-N 3Å; R70-N74 PolarHBondContact O-ND2 2.72Å; G71-N74 WeakPolarHBondContact O-CB 3.32Å; G71-N74 PolarHBondContact O-N 3.2Å; N74-Y77 PolarHBondContact O-N 3.43Å; N74-R78 WeakPolarHBondContact O-CG 3.3Å; N74-R78 PolarHBondContact O-N 2.96Å; N74-H149 PolarHBondContact N-NE2 3.29Å; N74-H149 PolarHBondContact OD1-CD2 3.26Å; N74-H149 PolarHBondContact OD1-NE2 2.72Å; N74-N150 PolarHBondContact OD1-ND2 2.87Å
75D84.1Confident85.2Confident91 Ų9159.5 Ų59.549%0.48732%0.315SS..Hα-helixtrans-67.5-41.9178.3-66.5-26.7000111.2G71 T72 G73 R78 T79G71-D75 PolarHBondContact O-N 2.94Å; G71-D75 VanDerWaalsContact O-N 3.14Å; T72-D75 PolarHBondContact O-N 2.89Å; G73-D75 PolarHBondContact O-N 2.98Å; D75-R78 PolarHBondContact O-N 3.01Å; D75-T79 WeakPolarHBondContact O-CG2 3.39Å; D75-T79 PolarHBondContact O-N 3.15Å; D75-T79 VanDerWaalsContact O-N 3.11Å; D75-T79 PolarHBondContact O-OG1 2.99Å
76N83.7Confident85.2Confident71 Ų7159 Ų5938%0.3831%0.308SS..Hα-helixtrans-62.1-42174-79.3-1.5000111.9T72 G73 T79 T80T72-N76 WeakPolarHBondContact O-CB 3.2Å; T72-N76 PolarHBondContact O-N 2.64Å; G73-N76 PolarHBondContact O-N 2.87Å; N76-T79 WeakPolarHBondContact CA-OG1 3.42Å; N76-T79 PolarHBondContact O-N 3.18Å; N76-T79 PolarHBondContact O-OG1 3.46Å; N76-T80 WeakPolarHBondContact O-CB 3.47Å; N76-T80 PolarHBondContact O-N 3.24Å; N76-T80 PolarHBondContact O-OG1 2.9Å
77Y87.1Confident85.2Confident85 Ų8555.3 Ų55.333%0.33329%0.292SS..Hα-helixtrans-63.6-42.5176.9179-115.4000111.8G73 N74 T79 G81 I82 A83 L105 H149G73-Y77 WeakPolarHBondContact O-CB 3.41Å; G73-Y77 PolarHBondContact O-N 3.27Å; N74-Y77 PolarHBondContact O-N 3.43Å; Y77-T79 VanDerWaalsContact C-N 3.28Å; Y77-T79 PolarHBondContact O-N 3.47Å; Y77-G81 VanDerWaalsContact O-CA 3.24Å; Y77-G81 WeakPolarHBondContact O-CA 3.43Å; Y77-G81 PolarHBondContact O-N 3.32Å; Y77-I82 WeakPolarHBondContact CA-O 3.43Å; Y77-I82 WeakPolarHBondContact CB-O 3.45Å; Y77-I82 WeakPolarHBondContact CD2-O 3.26Å; Y77-A83 HydrophobicContact CD2-CB 4.14Å; Y77-A83 HydrophobicContact CE2-CB 4.11Å; Y77-L105 HydrophobicContact CE2-CD1 4.29Å; Y77-H149 HydrophobicContact CD1-CB 3.92Å; Y77-H149 AromaticContact CD1-CG 3.95Å; Y77-H149 HydrophobicContact CD2-CB 4.32Å; Y77-H149 HydrophobicContact CE1-CB 4Å; Y77-H149 HydrophobicContact CE2-CB 4.4Å; Y77-H149 HydrophobicContact CG-CB 4.08Å; Y77-H149 AromaticContact CG-CG 3.83Å; Y77-H149 AromaticContact CG-ND1 3.76Å
78R86.4Confident85Confident210 Ų21055.3 Ų55.379%0.79229%0.287SS*.Hα-helixtrans-62.7-33.3177-75.3175.5175.9-170.3-1.3113.3N74 D75N74-R78 WeakPolarHBondContact O-CG 3.3Å; N74-R78 PolarHBondContact O-N 2.96Å; D75-R78 PolarHBondContact O-N 3.01Å
79T87.4Confident84.8Confident110 Ų11054.6 Ų54.668%0.67528%0.284SS*.Hα-helixtrans-90.7-38.2-175.546.50000113.4D75 N76 Y77D75-T79 WeakPolarHBondContact O-CG2 3.39Å; D75-T79 PolarHBondContact O-N 3.15Å; D75-T79 VanDerWaalsContact O-N 3.11Å; D75-T79 PolarHBondContact O-OG1 2.99Å; N76-T79 WeakPolarHBondContact CA-OG1 3.42Å; N76-T79 PolarHBondContact O-N 3.18Å; N76-T79 PolarHBondContact O-OG1 3.46Å; Y77-T79 VanDerWaalsContact C-N 3.28Å; Y77-T79 PolarHBondContact O-N 3.47Å
80T84.8Confident84.3Confident83 Ų8352.2 Ų52.251%0.50927%0.274SS..Hα-helixtrans-114.5-14.7-171.2670000114.2N76 I82N76-T80 WeakPolarHBondContact O-CB 3.47Å; N76-T80 PolarHBondContact O-N 3.24Å; N76-T80 PolarHBondContact O-OG1 2.9Å; T80-I82 PolarHBondContact O-N 2.94Å; T80-I82 PolarHBondContact OG1-N 3.49Å
81G83.4Confident83.6Confident40 Ų4049.1 Ų49.141%0.41227%0.269SS..  trans72.19.3-173.100000114.7Y77Y77-G81 VanDerWaalsContact O-CA 3.24Å; Y77-G81 WeakPolarHBondContact O-CA 3.43Å; Y77-G81 PolarHBondContact O-N 3.32Å
82I86.6Confident82.7Confident55 Ų5553.7 Ų53.728%0.28228%0.277SS..PPolyproline II helixtrans-85.5119.6177.8-60173.8000109.6Y77 T80 E102Y77-I82 WeakPolarHBondContact CA-O 3.43Å; Y77-I82 WeakPolarHBondContact CB-O 3.45Å; Y77-I82 WeakPolarHBondContact CD2-O 3.26Å; T80-I82 PolarHBondContact O-N 2.94Å; T80-I82 PolarHBondContact OG1-N 3.49Å; I82-E102 HydrophobicContact CG2-CB 3.88Å
83A87.4Confident82Confident0 Ų053.9 Ų53.90%028%0.276CS..EExtended strand (participates in β ladder)trans-88.1146.3179.500000111.6Y77 E102 T103 L105 H149Y77-A83 HydrophobicContact CD2-CB 4.14Å; Y77-A83 HydrophobicContact CE2-CB 4.11Å; A83-E102 CarbonylContact O-C 3.59Å; A83-E102 WeakPolarHBondContact O-CA 3.46Å; A83-T103 WeakPolarHBondContact CA-O 3.42Å; A83-T103 WeakPolarHBondContact CB-O 3.39Å; A83-T103 PolarHBondContact N-O 3.17Å; A83-T103 PolarHBondContact O-N 3.31Å; A83-T103 VanDerWaalsContact O-O 3.04Å; A83-L105 HydrophobicContact CB-CD1 4.36Å; A83-L105 HydrophobicContact CB-CD2 3.59Å; A83-L105 HydrophobicContact CB-CG 3.86Å; A83-H149 HydrophobicContact CB-CB 4.31Å
84T86.6Confident81Confident10 Ų1056.9 Ų56.96%0.06129%0.287CS..EExtended strand (participates in β ladder)trans-102.5133.2173.9-46.60000108.8L100 L101 H149 N150T84-L100 HydrophobicContact CG2-CB 4.11Å; T84-L100 HydrophobicContact CG2-CD2 4.04Å; T84-L100 HydrophobicContact CG2-CG 4.47Å; T84-L101 CarbonylContact C-O 3.6Å; T84-L101 WeakPolarHBondContact CA-O 3.45Å; T84-H149 PolarHBondContact N-ND1 3.2Å; T84-H149 VanDerWaalsContact N-ND1 3.14Å; T84-H149 PolarHBondContact OG1-CE1 3.22Å; T84-N150 VanDerWaalsContact O-CA 3.24Å; T84-N150 WeakPolarHBondContact O-CA 3.42Å; T84-N150 PolarHBondContact O-N 3.1Å
85I87.8Confident79.5Confident0 Ų060.2 Ų60.20%030%0.299CS..EExtended strand (participates in β ladder)trans-116.5129.1177.8-59.7178.8000108.2V87 L100 L101 T103 L112 L142 V147 V151 A153I85-V87 HydrophobicContact CG2-CG2 4.23Å; I85-L100 WeakPolarHBondContact O-CA 3.45Å; I85-L101 PolarHBondContact N-O 2.93Å; I85-L101 PolarHBondContact O-N 2.93Å; I85-T103 HydrophobicContact CD1-CG2 3.55Å; I85-T103 HydrophobicContact CG1-CG2 4.26Å; I85-L112 HydrophobicContact CD1-CD1 3.86Å; I85-L112 HydrophobicContact CD1-CD2 4.11Å; I85-L142 HydrophobicContact CD1-CD1 4.37Å; I85-V147 HydrophobicContact CD1-CG1 4.33Å; I85-V151 HydrophobicContact CG1-CG1 4.27Å; I85-V151 HydrophobicContact CG2-CG1 4.21Å; I85-A153 HydrophobicContact CG2-CB 3.57Å
86E86.6Confident77.9Confident34 Ų3464.4 Ų64.416%0.15932%0.321CS..EExtended strand (participates in β ladder)trans-88.5107.9175.9-169.3174.2-174.400109.4R70 F88 N99 L100 V151 K152 A153R70-E86 IonicContact NH2-OE2 2.78Å; R70-E86 PolarHBondContact NH2-OE2 2.97Å; E86-F88 HydrophobicContact CB-CE2 4.38Å; E86-F88 HydrophobicContact CG-CE2 3.78Å; E86-F88 HydrophobicContact CG-CZ 4.26Å; E86-N99 CarbonylContact C-O 3.5Å; E86-N99 WeakPolarHBondContact CA-O 3.36Å; E86-L100 HydrophobicContact CB-CD2 4.13Å; E86-L100 HydrophobicContact CG-CD2 4.19Å; E86-V151 PolarHBondContact N-O 3.5Å; E86-K152 HydrophobicContact CB-CG 4.5Å; E86-K152 CarbonylContact O-C 3.6Å; E86-K152 WeakPolarHBondContact O-CA 3.1Å; E86-A153 PolarHBondContact O-N 2.88Å
87V86.7Confident76.5Confident0 Ų069.1 Ų69.10%033%0.334CS..EExtended strand (participates in β ladder)trans-95.2113.1-171.6-175.20000111.2I85 L89 N99 L101 I116 F120 A153 V155I85-V87 HydrophobicContact CG2-CG2 4.23Å; V87-L89 HydrophobicContact CG1-CD2 3.93Å; V87-L89 HydrophobicContact CG1-CG 4.43Å; V87-L89 PolarHBondContact O-N 2.92Å; V87-N99 PolarHBondContact N-O 3.41Å; V87-N99 WeakPolarHBondContact O-CB 3.25Å; V87-L101 HydrophobicContact CG2-CB 3.88Å; V87-I116 HydrophobicContact CG1-CD1 4.49Å; V87-I116 HydrophobicContact CG1-CG2 4.38Å; V87-I116 HydrophobicContact CG2-CD1 4.39Å; V87-I116 HydrophobicContact CG2-CG1 4.46Å; V87-F120 HydrophobicContact CB-CE2 3.97Å; V87-F120 HydrophobicContact CB-CZ 4.09Å; V87-F120 HydrophobicContact CG1-CD2 4.34Å; V87-F120 HydrophobicContact CG1-CE2 3.86Å; V87-F120 HydrophobicContact CG1-CZ 4.35Å; V87-F120 HydrophobicContact CG2-CE2 4.03Å; V87-F120 HydrophobicContact CG2-CZ 4.36Å; V87-A153 CarbonylContact C-O 3.42Å; V87-A153 WeakPolarHBondContact CA-O 3.44Å; V87-V155 HydrophobicContact CG1-CG2 3.43Å; V87-V155 VanDerWaalsContact CG1-CG2 3.43Å
88F81.4Confident75.1Confident25 Ų2572.1 Ų72.111%0.1135%0.348CS..EExtended strand (participates in β ladder)trans-91.1106.4176.1-72.3-98.5000110.5E86 K152 A153 V155 Q296 E298 C299E86-F88 HydrophobicContact CB-CE2 4.38Å; E86-F88 HydrophobicContact CG-CE2 3.78Å; E86-F88 HydrophobicContact CG-CZ 4.26Å; F88-K152 HydrophobicContact CD2-CB 4.14Å; F88-K152 HydrophobicContact CE2-CB 3.79Å; F88-K152 HydrophobicContact CE2-CD 3.72Å; F88-K152 HydrophobicContact CE2-CG 3.71Å; F88-K152 HydrophobicContact CZ-CD 4.09Å; F88-K152 HydrophobicContact CZ-CG 4.49Å; F88-A153 PolarHBondContact N-O 3.32Å; F88-V155 PolarHBondContact O-N 3.44Å; F88-Q296 PolarHBondContact O-NE2 3.19Å; F88-E298 HydrophobicContact CE1-CB 3.94Å; F88-E298 HydrophobicContact CZ-CB 4.41Å; F88-C299 WeakPolarHBondContact CB-SG 3.29Å; F88-C299 WeakPolarHBondContact CD2-SG 3.4Å; F88-C299 WeakPolarHBondContact CG-SG 3.46Å
89L80.3Confident74.6Confident7 Ų764.4 Ų64.44%0.03732%0.323CS..  trans-82.2156.5-178.6-61.7172.1000112.4V87 L93 F120 L122 V155 Q296V87-L89 HydrophobicContact CG1-CD2 3.93Å; V87-L89 HydrophobicContact CG1-CG 4.43Å; V87-L89 PolarHBondContact O-N 2.92Å; L89-L93 HydrophobicContact CB-CB 4.31Å; L89-F120 HydrophobicContact CD1-CB 4.35Å; L89-F120 HydrophobicContact CD1-CD1 3.54Å; L89-F120 HydrophobicContact CD1-CE1 3.99Å; L89-F120 HydrophobicContact CD1-CG 3.99Å; L89-F120 HydrophobicContact CD2-CB 4.06Å; L89-F120 HydrophobicContact CD2-CD1 4.25Å; L89-F120 HydrophobicContact CD2-CD2 4.11Å; L89-F120 HydrophobicContact CD2-CG 3.87Å; L89-F120 HydrophobicContact CG-CD1 4.4Å; L89-L122 HydrophobicContact CD2-CD1 3.93Å; L89-V155 HydrophobicContact CD2-CB 4.4Å; L89-V155 HydrophobicContact CD2-CG2 4.38Å; L89-Q296 PolarHBondContact O-NE2 2.78Å
90P73.8Confident74.3Confident13 Ų1362.1 Ų62.18%0.08431%0.306CS..  trans-54.2151.1169.6-21.930.5000112.4R92 L93 K94 V155 E157P90-R92 VanDerWaalsContact C-N 3.26Å; P90-R92 PolarHBondContact O-N 2.96Å; P90-R92 VanDerWaalsContact O-N 3.09Å; P90-L93 PolarHBondContact O-N 3.25Å; P90-K94 PolarHBondContact O-N 2.97Å; P90-V155 WeakPolarHBondContact CD-O 3.44Å; P90-E157 HydrophobicContact CB-CB 4.25Å; P90-E157 HydrophobicContact CG-CB 3.48Å; P90-E157 VanDerWaalsContact CG-CB 3.48Å
91P67.6Low74.3Confident54 Ų5458.7 Ų58.735%0.35129%0.285SS..G310 helixtrans-49.7-39-176.2-29.735.7000115.4L93 K94 E295P91-L93 VanDerWaalsContact C-N 3.27Å; P91-L93 PolarHBondContact O-N 3.39Å; P91-K94 WeakPolarHBondContact O-CB 3.44Å; P91-K94 PolarHBondContact O-N 3.33Å; P91-E295 WeakPolarHBondContact CB-OE2 3.45Å; P91-E295 HydrophobicContact CG-CB 4.19Å; P91-E295 HydrophobicContact CG-CG 4.06Å; P91-E295 WeakPolarHBondContact CG-OE2 3.47Å
92R65.7Low74.6Confident126 Ų12662.4 Ų62.448%0.47529%0.291SS..G310 helixtrans-63.2-30.5179.7-63.8-172.3-174.9120.510.8114.1P90 K159 S161P90-R92 VanDerWaalsContact C-N 3.26Å; P90-R92 PolarHBondContact O-N 2.96Å; P90-R92 VanDerWaalsContact O-N 3.09Å; R92-K159 PolarHBondContact NH1-O 3.49Å; R92-S161 PolarHBondContact NE-OG 3.11Å; R92-S161 PolarHBondContact NH2-OG 3.27Å
93L67.1Low74.7Confident45 Ų4559.9 Ų59.924%0.23628%0.279CS..G310 helixtrans-100.76.3-174.7-65170.4000112.5L89 P90 P91 K95 L122L89-L93 HydrophobicContact CB-CB 4.31Å; P90-L93 PolarHBondContact O-N 3.25Å; P91-L93 VanDerWaalsContact C-N 3.27Å; P91-L93 PolarHBondContact O-N 3.39Å; L93-K95 PolarHBondContact O-N 2.94Å; L93-L122 HydrophobicContact CD1-CD1 4.4Å; L93-L122 HydrophobicContact CD1-CD2 3.19Å; L93-L122 HydrophobicContact CD1-CG 3.88Å
94K61.9Low74.7Confident69 Ų6966.6 Ų66.630%0.330%0.304SS..  trans-66.476.1169.7-68.5177.5-176.8166.60109.5M1 P90 P91 E295M1-K94 HydrophobicContact CE-CD 3.88Å; M1-K94 HydrophobicContact SD-CD 3.86Å; M1-K94 PolarHBondContact SD-NZ 3.49Å; P90-K94 PolarHBondContact O-N 2.97Å; P91-K94 WeakPolarHBondContact O-CB 3.44Å; P91-K94 PolarHBondContact O-N 3.33Å; K94-E295 IonicContact NZ-OE2 2.69Å; K94-E295 PolarHBondContact NZ-OE2 3.14Å
95K53.9Low74.7Confident137 Ų13767.1 Ų67.160%0.59631%0.306SS*.  trans-82.5156160.7-68.1-178.7178.7174.30108L93 R97L93-K95 PolarHBondContact O-N 2.94Å; K95-R97 HydrophobicContact CB-CG 4.22Å; K95-R97 PolarHBondContact O-N 3.34Å
96D49.8Very low74.7Confident179 Ų17972.6 Ų72.696%0.95733%0.332SS*.SBendtrans-64.123.8172.7-67.9-42.9000113.9
97R53.2Low74.8Confident170 Ų17071.4 Ų71.464%0.64233%0.326SS*.SBendtrans-81.8151.6177.9-71.5-173.4176.3-174-1.8110.3K95 N99K95-R97 HydrophobicContact CB-CG 4.22Å; K95-R97 PolarHBondContact O-N 3.34Å; R97-N99 PolarHBondContact O-N 2.98Å; R97-N99 VanDerWaalsContact O-N 3.09Å; R97-N99 PolarHBondContact O-OD1 3.4Å
98K59.3Low75Confident147 Ų14773.3 Ų73.364%0.63934%0.338SS*.  trans-61.9114174.9-61.3-167.8-177.4-155.80109.2E69 L100E69-K98 WeakPolarHBondContact OE1-CE 3.27Å; E69-K98 IonicContact OE1-NZ 3.49Å; E69-K98 PolarHBondContact OE1-NZ 2.97Å; K98-L100 PolarHBondContact O-N 2.84Å
99N75Confident75.3Confident48 Ų4872.1 Ų72.126%0.25733%0.333SS..  trans-77.934.1176.1-77.4-10.3000111.9E86 V87 R97E86-N99 CarbonylContact C-O 3.5Å; E86-N99 WeakPolarHBondContact CA-O 3.36Å; V87-N99 PolarHBondContact N-O 3.41Å; V87-N99 WeakPolarHBondContact O-CB 3.25Å; R97-N99 PolarHBondContact O-N 2.98Å; R97-N99 VanDerWaalsContact O-N 3.09Å; R97-N99 PolarHBondContact O-OD1 3.4Å
100L80.4Confident75.6Confident63 Ų6378.9 Ų78.933%0.3336%0.358SS..EExtended strand (participates in β ladder)trans-114.8130.5-175.9-63.8174.8000109.2T84 I85 E86 K98T84-L100 HydrophobicContact CG2-CB 4.11Å; T84-L100 HydrophobicContact CG2-CD2 4.04Å; T84-L100 HydrophobicContact CG2-CG 4.47Å; I85-L100 WeakPolarHBondContact O-CA 3.45Å; E86-L100 HydrophobicContact CB-CD2 4.13Å; E86-L100 HydrophobicContact CG-CD2 4.19Å; K98-L100 PolarHBondContact O-N 2.84Å
101L86.7Confident76.2Confident11 Ų1182.5 Ų82.56%0.05837%0.374CS..EExtended strand (participates in β ladder)trans-119.9127.5176.7-174.477.3000109.8T84 I85 V87 L112 K115 I116 T119T84-L101 CarbonylContact C-O 3.6Å; T84-L101 WeakPolarHBondContact CA-O 3.45Å; I85-L101 PolarHBondContact N-O 2.93Å; I85-L101 PolarHBondContact O-N 2.93Å; V87-L101 HydrophobicContact CG2-CB 3.88Å; L101-L112 HydrophobicContact CD2-CD1 3.54Å; L101-K115 HydrophobicContact CD2-CB 4.26Å; L101-I116 HydrophobicContact CD2-CD1 4.35Å; L101-I116 HydrophobicContact CD2-CG1 3.62Å; L101-T119 HydrophobicContact CD1-CG2 4.21Å; L101-T119 WeakPolarHBondContact CD1-OG1 3.29Å
102E87.8Confident77.3Confident117 Ų11780 Ų8055%0.54736%0.357SS..EExtended strand (participates in β ladder)trans-95.3127.2175.9-66.7-176.3166.300110.6I82 A83I82-E102 HydrophobicContact CG2-CB 3.88Å; A83-E102 CarbonylContact O-C 3.59Å; A83-E102 WeakPolarHBondContact O-CA 3.46Å
103T88.8Confident78.3Confident3 Ų375.3 Ų75.32%0.01834%0.339CS..EExtended strand (participates in β ladder)trans-154.7158.9179.1-165.20000112.8A83 I85 I107 L112 K115 L142A83-T103 WeakPolarHBondContact CA-O 3.42Å; A83-T103 WeakPolarHBondContact CB-O 3.39Å; A83-T103 PolarHBondContact N-O 3.17Å; A83-T103 PolarHBondContact O-N 3.31Å; A83-T103 VanDerWaalsContact O-O 3.04Å; I85-T103 HydrophobicContact CD1-CG2 3.55Å; I85-T103 HydrophobicContact CG1-CG2 4.26Å; T103-I107 HydrophobicContact CG2-CD1 4.32Å; T103-I107 WeakPolarHBondContact OG1-CD1 3.44Å; T103-L112 HydrophobicContact CG2-CD1 4.28Å; T103-K115 PolarHBondContact OG1-NZ 3.18Å; T103-L142 HydrophobicContact CG2-CD1 4.1Å
104R88Confident79.3Confident141 Ų14175 Ų7553%0.53234%0.341SS..  trans-81.8150.5171.1-56.6-173.1-177.9167.4-7.3109.8H106 I107R104-H106 WeakPolarHBondContact CD-CE1 3.15Å; R104-I107 HydrophobicContact CB-CG2 4.43Å; R104-I107 WeakPolarHBondContact O-CG1 3.31Å
105L87.5Confident80.6Confident21 Ų2175 Ų7511%0.1134%0.341CS..THydrogen-bonded Turntrans-80.9-15.6-176.4-61.9178.3000114.3Y77 A83 I107 L142 E143 V147Y77-L105 HydrophobicContact CE2-CD1 4.29Å; A83-L105 HydrophobicContact CB-CD1 4.36Å; A83-L105 HydrophobicContact CB-CD2 3.59Å; A83-L105 HydrophobicContact CB-CG 3.86Å; L105-I107 VanDerWaalsContact C-N 3.27Å; L105-I107 PolarHBondContact O-N 3.36Å; L105-L142 WeakPolarHBondContact O-CB 3.33Å; L105-L142 PolarHBondContact O-N 3.38Å; L105-E143 HydrophobicContact CB-CB 4.42Å; L105-E143 PolarHBondContact O-N 3.38Å; L105-E143 VanDerWaalsContact O-N 3.12Å; L105-V147 HydrophobicContact CD2-CG1 4.27Å
106H86.8Confident82.2Confident115 Ų11568.5 Ų68.553%0.53231%0.313SS..THydrogen-bonded Turntrans-80.2-4.2177.759.5-106.9000114.2R104R104-H106 WeakPolarHBondContact CD-CE1 3.15Å
107I90.1Very high83.9Confident9 Ų960.3 Ų60.35%0.04627%0.27CS..SBendtrans-70.7158.1177.472.4164.7000110.8T103 R104 L105 E111 L112 K115 T141 L142T103-I107 HydrophobicContact CG2-CD1 4.32Å; T103-I107 WeakPolarHBondContact OG1-CD1 3.44Å; R104-I107 HydrophobicContact CB-CG2 4.43Å; R104-I107 WeakPolarHBondContact O-CG1 3.31Å; L105-I107 VanDerWaalsContact C-N 3.27Å; L105-I107 PolarHBondContact O-N 3.36Å; I107-E111 HydrophobicContact CB-CB 4.15Å; I107-E111 VanDerWaalsContact CB-OE2 3.26Å; I107-E111 WeakPolarHBondContact CB-OE2 3.48Å; I107-E111 HydrophobicContact CD1-CB 4.07Å; I107-E111 WeakPolarHBondContact CG2-OE2 3.35Å; I107-L112 HydrophobicContact CD1-CB 3.95Å; I107-K115 HydrophobicContact CD1-CD 4.4Å; I107-T141 CarbonylContact O-C 3.28Å; I107-T141 VanDerWaalsContact O-CA 3.29Å; I107-T141 WeakPolarHBondContact O-CA 3.22Å; I107-L142 HydrophobicContact CD1-CD1 3.95Å; I107-L142 HydrophobicContact CG1-CD1 3.53Å; I107-L142 HydrophobicContact CG1-CG 3.9Å; I107-L142 PolarHBondContact O-N 2.83Å
108T90.4Very high85.5Confident39 Ų3960.2 Ų60.224%0.23928%0.277CS..BIsolated β-bridgetrans-76.8158.8174.5620000112.5R110 E111 L112 K140T108-R110 PolarHBondContact O-N 2.96Å; T108-E111 PolarHBondContact N-OE1 3.36Å; T108-E111 PolarHBondContact O-N 2.96Å; T108-E111 VanDerWaalsContact O-N 3.17Å; T108-E111 WeakPolarHBondContact OG1-CG 3.49Å; T108-E111 PolarHBondContact OG1-N 2.98Å; T108-E111 PolarHBondContact OG1-OE1 2.71Å; T108-L112 PolarHBondContact O-N 3.01Å; T108-L112 VanDerWaalsContact O-N 3.1Å; T108-K140 WeakPolarHBondContact CA-O 3.36Å
109G87Confident86.7Confident0 Ų056.6 Ų56.60%027%0.267CS..Hα-helixtrans-58.6-30.6172.100000113.2R113 K140G109-R113 PolarHBondContact O-N 3.17Å; G109-R113 VanDerWaalsContact O-N 3.09Å; G109-K140 PolarHBondContact N-O 2.8Å
110R86.7Confident87Confident150 Ų15055.6 Ų55.657%0.56626%0.261SS*.Hα-helixtrans-63.2-49173-173.9-177.9-65.6178.4-0.8111.6T108 L112 R113 S114 L138T108-R110 PolarHBondContact O-N 2.96Å; R110-L112 VanDerWaalsContact C-N 3.31Å; R110-L112 PolarHBondContact O-N 3.15Å; R110-R113 WeakPolarHBondContact O-CB 3.42Å; R110-R113 PolarHBondContact O-N 2.97Å; R110-R113 VanDerWaalsContact O-N 3.11Å; R110-S114 PolarHBondContact O-N 3.43Å; R110-S114 PolarHBondContact O-OG 2.97Å; R110-L138 HydrophobicContact CB-CB 4.3Å; R110-L138 PolarHBondContact N-O 3.34Å
111E87.4Confident86.8Confident89 Ų8956 Ų5642%0.41628%0.279SS..Hα-helixtrans-62.1-38.8178.4-72.8160-119.500112.2I107 T108 R113 S114 K115I107-E111 HydrophobicContact CB-CB 4.15Å; I107-E111 VanDerWaalsContact CB-OE2 3.26Å; I107-E111 WeakPolarHBondContact CB-OE2 3.48Å; I107-E111 HydrophobicContact CD1-CB 4.07Å; I107-E111 WeakPolarHBondContact CG2-OE2 3.35Å; T108-E111 PolarHBondContact N-OE1 3.36Å; T108-E111 PolarHBondContact O-N 2.96Å; T108-E111 VanDerWaalsContact O-N 3.17Å; T108-E111 WeakPolarHBondContact OG1-CG 3.49Å; T108-E111 PolarHBondContact OG1-N 2.98Å; T108-E111 PolarHBondContact OG1-OE1 2.71Å; E111-R113 VanDerWaalsContact C-N 3.29Å; E111-R113 PolarHBondContact O-N 3.35Å; E111-S114 PolarHBondContact O-N 3.45Å; E111-K115 WeakPolarHBondContact O-CG 3.37Å; E111-K115 PolarHBondContact O-N 2.88Å
112L89.7Confident86.4Confident0 Ų056.1 Ų56.10%028%0.28CS..Hα-helixtrans-62-41.1174.9178.860.7000111I85 L101 T103 I107 T108 R110 K115 I116 I131 L136 L142I85-L112 HydrophobicContact CD1-CD1 3.86Å; I85-L112 HydrophobicContact CD1-CD2 4.11Å; L101-L112 HydrophobicContact CD2-CD1 3.54Å; T103-L112 HydrophobicContact CG2-CD1 4.28Å; I107-L112 HydrophobicContact CD1-CB 3.95Å; T108-L112 PolarHBondContact O-N 3.01Å; T108-L112 VanDerWaalsContact O-N 3.1Å; R110-L112 VanDerWaalsContact C-N 3.31Å; R110-L112 PolarHBondContact O-N 3.15Å; L112-K115 PolarHBondContact O-N 2.67Å; L112-I116 HydrophobicContact CD1-CD1 4.04Å; L112-I116 HydrophobicContact CD1-CG1 4.31Å; L112-I116 HydrophobicContact CG-CD1 4.01Å; L112-I116 WeakPolarHBondContact O-CG1 3.42Å; L112-I116 PolarHBondContact O-N 2.99Å; L112-I131 HydrophobicContact CD2-CD1 3.72Å; L112-L136 HydrophobicContact CB-CD2 4.45Å; L112-L136 HydrophobicContact CD2-CD2 3.98Å; L112-L136 HydrophobicContact CG-CD2 4.48Å; L112-L142 HydrophobicContact CB-CD1 4.28Å; L112-L142 HydrophobicContact CB-CD2 4.05Å; L112-L142 HydrophobicContact CD1-CD1 4.48Å; L112-L142 HydrophobicContact CD2-CD1 3.9Å; L112-L142 HydrophobicContact CD2-CD2 3.52Å; L112-L142 HydrophobicContact CD2-CG 4.38Å; L112-L142 HydrophobicContact CG-CD1 4.45Å; L112-L142 HydrophobicContact CG-CD2 4.4Å
113R87.9Confident85.6Confident28 Ų2853.7 Ų53.711%0.10627%0.269CS..Hα-helixtrans-61.9-48176.2-168.4-179.964.6163.26.7111.7G109 R110 E111 K115 I116 A117 E124 I127 I129 L138G109-R113 PolarHBondContact O-N 3.17Å; G109-R113 VanDerWaalsContact O-N 3.09Å; R110-R113 WeakPolarHBondContact O-CB 3.42Å; R110-R113 PolarHBondContact O-N 2.97Å; R110-R113 VanDerWaalsContact O-N 3.11Å; E111-R113 VanDerWaalsContact C-N 3.29Å; E111-R113 PolarHBondContact O-N 3.35Å; R113-K115 VanDerWaalsContact C-N 3.33Å; R113-K115 PolarHBondContact O-N 3.24Å; R113-I116 PolarHBondContact O-N 2.95Å; R113-A117 WeakPolarHBondContact O-CB 3.36Å; R113-A117 PolarHBondContact O-N 3.31Å; R113-E124 WeakPolarHBondContact CD-O 3.32Å; R113-E124 HydrophobicContact CG-CG 3.93Å; R113-E124 IonicContact CZ-OE1 3.24Å; R113-E124 PolarHBondContact NE-O 3.41Å; R113-E124 IonicContact NE-OE1 3.63Å; R113-E124 PolarHBondContact NE-OE1 3.16Å; R113-E124 IonicContact NH2-OE1 3.64Å; R113-E124 PolarHBondContact NH2-OE1 2.97Å; R113-I127 HydrophobicContact CG-CD1 3.56Å; R113-I127 HydrophobicContact CG-CG1 3.64Å; R113-I129 HydrophobicContact CB-CD1 3.81Å; R113-I129 HydrophobicContact CG-CD1 3.93Å; R113-L138 HydrophobicContact CB-CD2 4.4Å
114S87.2Confident85Confident38 Ų3856.4 Ų56.427%0.26628%0.281SS..Hα-helixtrans-59.4-42.6176-53.10000111.9R110 E111 A117 E118 E124R110-S114 PolarHBondContact O-N 3.43Å; R110-S114 PolarHBondContact O-OG 2.97Å; E111-S114 PolarHBondContact O-N 3.45Å; S114-A117 WeakPolarHBondContact O-CB 3.02Å; S114-A117 PolarHBondContact O-N 2.77Å; S114-E118 WeakPolarHBondContact O-CB 3.41Å; S114-E118 PolarHBondContact O-N 2.87Å; S114-E124 WeakPolarHBondContact CB-OE2 3.37Å; S114-E124 PolarHBondContact OG-OE1 3.36Å; S114-E124 PolarHBondContact OG-OE2 2.85Å
115K89.3Confident84.2Confident70 Ų7053.4 Ų53.430%0.30428%0.276SS..Hα-helixtrans-62.8-43.9176.5-75.9-176.3-178.9-173.10113.1L101 T103 I107 E111 L112 R113 A117 E118 T119L101-K115 HydrophobicContact CD2-CB 4.26Å; T103-K115 PolarHBondContact OG1-NZ 3.18Å; I107-K115 HydrophobicContact CD1-CD 4.4Å; E111-K115 WeakPolarHBondContact O-CG 3.37Å; E111-K115 PolarHBondContact O-N 2.88Å; L112-K115 PolarHBondContact O-N 2.67Å; R113-K115 VanDerWaalsContact C-N 3.33Å; R113-K115 PolarHBondContact O-N 3.24Å; K115-A117 VanDerWaalsContact C-N 3.33Å; K115-E118 PolarHBondContact O-N 2.88Å; K115-T119 VanDerWaalsContact O-CB 3.25Å; K115-T119 WeakPolarHBondContact O-CB 3.48Å; K115-T119 PolarHBondContact O-N 3.32Å; K115-T119 PolarHBondContact O-OG1 3.14Å
116I88.1Confident83.4Confident0 Ų052.9 Ų52.90%027%0.272CS..Hα-helixtrans-64.2-42.7176.6-72.3172.7000109.9V87 L101 L112 R113 F120 L122 I127 I129 V155V87-I116 HydrophobicContact CG1-CD1 4.49Å; V87-I116 HydrophobicContact CG1-CG2 4.38Å; V87-I116 HydrophobicContact CG2-CD1 4.39Å; V87-I116 HydrophobicContact CG2-CG1 4.46Å; L101-I116 HydrophobicContact CD2-CD1 4.35Å; L101-I116 HydrophobicContact CD2-CG1 3.62Å; L112-I116 HydrophobicContact CD1-CD1 4.04Å; L112-I116 HydrophobicContact CD1-CG1 4.31Å; L112-I116 HydrophobicContact CG-CD1 4.01Å; L112-I116 WeakPolarHBondContact O-CG1 3.42Å; L112-I116 PolarHBondContact O-N 2.99Å; R113-I116 PolarHBondContact O-N 2.95Å; I116-F120 HydrophobicContact CG2-CD2 4.02Å; I116-F120 WeakPolarHBondContact O-CD2 3.44Å; I116-F120 PolarHBondContact O-N 3.48Å; I116-F120 VanDerWaalsContact O-N 3.11Å; I116-L122 HydrophobicContact CG2-CD1 4.31Å; I116-I127 HydrophobicContact CB-CD1 4.37Å; I116-I127 HydrophobicContact CG2-CD1 4.03Å; I116-I129 HydrophobicContact CD1-CD1 3.67Å; I116-I129 HydrophobicContact CD1-CG1 4.18Å; I116-V155 HydrophobicContact CD1-CG2 4.47Å; I116-V155 HydrophobicContact CG2-CG2 3.85Å
117A85.3Confident83Confident7 Ų747.6 Ų47.66%0.05825%0.248CC..Hα-helixtrans-55.6-53.3176.300000111.5R113 S114 K115 G121 L122 E124 I127R113-A117 WeakPolarHBondContact O-CB 3.36Å; R113-A117 PolarHBondContact O-N 3.31Å; S114-A117 WeakPolarHBondContact O-CB 3.02Å; S114-A117 PolarHBondContact O-N 2.77Å; K115-A117 VanDerWaalsContact C-N 3.33Å; A117-G121 CarbonylContact O-C 3.55Å; A117-G121 WeakPolarHBondContact O-CA 3.46Å; A117-G121 PolarHBondContact O-N 2.99Å; A117-L122 CarbonylContact C-O 3.56Å; A117-L122 WeakPolarHBondContact CA-O 3.34Å; A117-L122 VanDerWaalsContact CB-O 3.31Å; A117-L122 WeakPolarHBondContact CB-O 3.41Å; A117-L122 PolarHBondContact O-N 3.4Å; A117-E124 HydrophobicContact CB-CB 3.85Å; A117-E124 HydrophobicContact CB-CG 4.16Å; A117-I127 HydrophobicContact CB-CD1 4.02Å
118E85.8Confident82.7Confident168 Ų16848.3 Ų48.379%0.78525%0.251SS*.Hα-helixtrans-66.2-44.6-178.2-167175.6-163.600112.6S114 K115 F120S114-E118 WeakPolarHBondContact O-CB 3.41Å; S114-E118 PolarHBondContact O-N 2.87Å; K115-E118 PolarHBondContact O-N 2.88Å; E118-F120 PolarHBondContact O-N 3.23Å
119T84.8Confident82.5Confident71 Ų7146.7 Ų46.744%0.43624%0.241SC..Hα-helixtrans-66.8-38.6-175.7-55.50000112.3L101 K115L101-T119 HydrophobicContact CD1-CG2 4.21Å; L101-T119 WeakPolarHBondContact CD1-OG1 3.29Å; K115-T119 VanDerWaalsContact O-CB 3.25Å; K115-T119 WeakPolarHBondContact O-CB 3.48Å; K115-T119 PolarHBondContact O-N 3.32Å; K115-T119 PolarHBondContact O-OG1 3.14Å
120F82.1Confident82.4Confident28 Ų2847 Ų4712%0.12324%0.243CC..Hα-helixtrans-104.83.4-173.4-61-71.4000113.6V87 L89 I116 E118 L122V87-F120 HydrophobicContact CB-CE2 3.97Å; V87-F120 HydrophobicContact CB-CZ 4.09Å; V87-F120 HydrophobicContact CG1-CD2 4.34Å; V87-F120 HydrophobicContact CG1-CE2 3.86Å; V87-F120 HydrophobicContact CG1-CZ 4.35Å; V87-F120 HydrophobicContact CG2-CE2 4.03Å; V87-F120 HydrophobicContact CG2-CZ 4.36Å; L89-F120 HydrophobicContact CD1-CB 4.35Å; L89-F120 HydrophobicContact CD1-CD1 3.54Å; L89-F120 HydrophobicContact CD1-CE1 3.99Å; L89-F120 HydrophobicContact CD1-CG 3.99Å; L89-F120 HydrophobicContact CD2-CB 4.06Å; L89-F120 HydrophobicContact CD2-CD1 4.25Å; L89-F120 HydrophobicContact CD2-CD2 4.11Å; L89-F120 HydrophobicContact CD2-CG 3.87Å; L89-F120 HydrophobicContact CG-CD1 4.4Å; I116-F120 HydrophobicContact CG2-CD2 4.02Å; I116-F120 WeakPolarHBondContact O-CD2 3.44Å; I116-F120 PolarHBondContact O-N 3.48Å; I116-F120 VanDerWaalsContact O-N 3.11Å; E118-F120 PolarHBondContact O-N 3.23Å; F120-L122 VanDerWaalsContact C-N 3.32Å; F120-L122 HydrophobicContact CB-CD1 4Å; F120-L122 HydrophobicContact CB-CG 4.36Å
121G76.4Confident82.3Confident70 Ų7040.3 Ų40.372%0.72222%0.218SC*.THydrogen-bonded Turntrans67.734.1179.500000112.8A117A117-G121 CarbonylContact O-C 3.55Å; A117-G121 WeakPolarHBondContact O-CA 3.46Å; A117-G121 PolarHBondContact O-N 2.99Å
122L78.2Confident81.9Confident15 Ų1539.5 Ų39.58%0.07922%0.216CC..  trans-97.4149.7179-78.6164.4000109.7L89 L93 I116 A117 F120 I127 V155L89-L122 HydrophobicContact CD2-CD1 3.93Å; L93-L122 HydrophobicContact CD1-CD1 4.4Å; L93-L122 HydrophobicContact CD1-CD2 3.19Å; L93-L122 HydrophobicContact CD1-CG 3.88Å; I116-L122 HydrophobicContact CG2-CD1 4.31Å; A117-L122 CarbonylContact C-O 3.56Å; A117-L122 WeakPolarHBondContact CA-O 3.34Å; A117-L122 VanDerWaalsContact CB-O 3.31Å; A117-L122 WeakPolarHBondContact CB-O 3.41Å; A117-L122 PolarHBondContact O-N 3.4Å; F120-L122 VanDerWaalsContact C-N 3.32Å; F120-L122 HydrophobicContact CB-CD1 4Å; F120-L122 HydrophobicContact CB-CG 4.36Å; L122-I127 HydrophobicContact CB-CG2 3.92Å; L122-I127 HydrophobicContact CD1-CG2 4Å; L122-I127 HydrophobicContact CD2-CG2 3.94Å; L122-I127 HydrophobicContact CG-CG2 4.19Å; L122-V155 HydrophobicContact CD1-CG1 3.95Å
123Q71.4Confident81.2Confident65 Ų6543.2 Ų43.230%0.30423%0.232SC..  trans-80.8123.2173.3-68175.4-27.700109.8N125 Y126Q123-N125 PolarHBondContact O-N 3.46Å; Q123-N125 VanDerWaalsContact O-N 3.1Å; Q123-Y126 HydrophobicContact CB-CD2 3.18Å; Q123-Y126 HydrophobicContact CB-CE2 3.6Å; Q123-Y126 HydrophobicContact CB-CG 4.09Å; Q123-Y126 HydrophobicContact CG-CD2 4.2Å; Q123-Y126 HydrophobicContact CG-CE2 4.22Å; Q123-Y126 PolarHBondContact O-N 2.91Å; Q123-Y126 VanDerWaalsContact OE1-CD2 3.27Å
124E75.1Confident80.9Confident60 Ų6048.9 Ų48.928%0.2826%0.258SS..G310 helixtrans-54.9-36.3-171.1-164.2-165134.300113.8R113 S114 A117 Y126 I127R113-E124 WeakPolarHBondContact CD-O 3.32Å; R113-E124 HydrophobicContact CG-CG 3.93Å; R113-E124 IonicContact CZ-OE1 3.24Å; R113-E124 PolarHBondContact NE-O 3.41Å; R113-E124 IonicContact NE-OE1 3.63Å; R113-E124 PolarHBondContact NE-OE1 3.16Å; R113-E124 IonicContact NH2-OE1 3.64Å; R113-E124 PolarHBondContact NH2-OE1 2.97Å; S114-E124 WeakPolarHBondContact CB-OE2 3.37Å; S114-E124 PolarHBondContact OG-OE1 3.36Å; S114-E124 PolarHBondContact OG-OE2 2.85Å; A117-E124 HydrophobicContact CB-CB 3.85Å; A117-E124 HydrophobicContact CB-CG 4.16Å; E124-Y126 VanDerWaalsContact C-N 3.27Å; E124-Y126 PolarHBondContact O-N 3.22Å; E124-I127 VanDerWaalsContact O-CG1 3.3Å; E124-I127 WeakPolarHBondContact O-CG1 3.42Å
125N70.8Confident80.7Confident78 Ų7849.9 Ų49.942%0.41726%0.258SS..G310 helixtrans-76.1-11.5-177.2-63.9-25.1000114Q123Q123-N125 PolarHBondContact O-N 3.46Å; Q123-N125 VanDerWaalsContact O-N 3.1Å
126Y70.3Confident80.6Confident10 Ų1047.1 Ų47.14%0.03925%0.247CC..G310 helixtrans-106.4-1.7-172.2-62.1-102.5000113.1Q123 E124 L158 K159 E175 Q176 A179Q123-Y126 HydrophobicContact CB-CD2 3.18Å; Q123-Y126 HydrophobicContact CB-CE2 3.6Å; Q123-Y126 HydrophobicContact CB-CG 4.09Å; Q123-Y126 HydrophobicContact CG-CD2 4.2Å; Q123-Y126 HydrophobicContact CG-CE2 4.22Å; Q123-Y126 PolarHBondContact O-N 2.91Å; Q123-Y126 VanDerWaalsContact OE1-CD2 3.27Å; E124-Y126 VanDerWaalsContact C-N 3.27Å; E124-Y126 PolarHBondContact O-N 3.22Å; Y126-L158 PolarHBondContact O-N 2.76Å; Y126-K159 HydrophobicContact CD1-CD 4.35Å; Y126-K159 HydrophobicContact CD1-CG 4.08Å; Y126-E175 WeakPolarHBondContact CE1-O 3.24Å; Y126-E175 PolarHBondContact OH-O 2.87Å; Y126-Q176 WeakPolarHBondContact OH-CA 3.1Å; Y126-Q176 WeakPolarHBondContact OH-CG 3.44Å; Y126-Q176 PolarHBondContact OH-N 3.47Å; Y126-A179 HydrophobicContact CD1-CB 3.26Å; Y126-A179 HydrophobicContact CD2-CB 4.27Å; Y126-A179 HydrophobicContact CE1-CB 3Å; Y126-A179 HydrophobicContact CE2-CB 4.07Å; Y126-A179 HydrophobicContact CG-CB 3.93Å; Y126-A179 VanDerWaalsContact CZ-CB 3.47Å
127I79.9Confident80.5Confident5 Ų551.1 Ų51.13%0.02627%0.266CS..EExtended strand (participates in β ladder)trans-107.4123.8-175.957.5165.1000110.1R113 I116 A117 L122 E124 V155 L156R113-I127 HydrophobicContact CG-CD1 3.56Å; R113-I127 HydrophobicContact CG-CG1 3.64Å; I116-I127 HydrophobicContact CB-CD1 4.37Å; I116-I127 HydrophobicContact CG2-CD1 4.03Å; A117-I127 HydrophobicContact CB-CD1 4.02Å; L122-I127 HydrophobicContact CB-CG2 3.92Å; L122-I127 HydrophobicContact CD1-CG2 4Å; L122-I127 HydrophobicContact CD2-CG2 3.94Å; L122-I127 HydrophobicContact CG-CG2 4.19Å; E124-I127 VanDerWaalsContact O-CG1 3.3Å; E124-I127 WeakPolarHBondContact O-CG1 3.42Å; I127-V155 HydrophobicContact CB-CG1 4.07Å; I127-V155 HydrophobicContact CG2-CG1 3.98Å; I127-L156 WeakPolarHBondContact CA-O 3.24Å
128K82.3Confident80.4Confident24 Ų2453.4 Ų53.410%0.10428%0.277CS..EExtended strand (participates in β ladder)trans-101.9136.1162.7-80.9-173.2176.2-165.60108.8L156 L158 P257K128-L156 HydrophobicContact CB-CB 4.13Å; K128-L156 HydrophobicContact CB-CD1 4.44Å; K128-L156 PolarHBondContact N-O 3.49Å; K128-L156 PolarHBondContact O-N 3.12Å; K128-L158 HydrophobicContact CD-CD1 4.19Å; K128-L158 HydrophobicContact CD-CD2 4.31Å; K128-L158 HydrophobicContact CG-CD1 4.09Å; K128-P257 HydrophobicContact CD-CB 4.14Å; K128-P257 HydrophobicContact CD-CG 3.59Å; K128-P257 VanDerWaalsContact NZ-CB 3.31Å
129I85.9Confident80.2Confident5 Ų548.9 Ų48.93%0.02628%0.275CS..EExtended strand (participates in β ladder)trans-109.9128.1-180-63158.5000107.9R113 I116 I131 L136 A153 M154R113-I129 HydrophobicContact CB-CD1 3.81Å; R113-I129 HydrophobicContact CG-CD1 3.93Å; I116-I129 HydrophobicContact CD1-CD1 3.67Å; I116-I129 HydrophobicContact CD1-CG1 4.18Å; I129-I131 HydrophobicContact CG2-CD1 3.74Å; I129-I131 HydrophobicContact CG2-CG1 3.76Å; I129-L136 HydrophobicContact CB-CB 4.04Å; I129-L136 HydrophobicContact CB-CD2 3.92Å; I129-L136 HydrophobicContact CD1-CD2 3.93Å; I129-L136 HydrophobicContact CG2-CB 4.21Å; I129-L136 HydrophobicContact CG2-CD2 3.97Å; I129-L136 VanDerWaalsContact O-CB 3.29Å; I129-L136 WeakPolarHBondContact O-CB 3.47Å; I129-L136 PolarHBondContact O-N 2.89Å; I129-A153 HydrophobicContact CG2-CB 4.29Å; I129-M154 CarbonylContact C-O 3.52Å; I129-M154 WeakPolarHBondContact CA-O 3.31Å
130V85Confident80.3Confident7 Ų750 Ų504%0.04227%0.274CS..EExtended strand (participates in β ladder)trans-112.1118.9174.1178.90000107.9K134 M154 L156 L260V130-K134 WeakPolarHBondContact CA-O 3.43Å; V130-M154 HydrophobicContact CB-CB 4.15Å; V130-M154 HydrophobicContact CB-CG 4.33Å; V130-M154 PolarHBondContact N-O 2.92Å; V130-M154 PolarHBondContact O-N 3.01Å; V130-L156 HydrophobicContact CG2-CD1 3.87Å; V130-L156 HydrophobicContact CG2-CG 4.43Å; V130-L260 HydrophobicContact CG1-CD1 3.75Å; V130-L260 HydrophobicContact CG2-CD1 4.02Å
131I85.6Confident80.7Confident9 Ų950.1 Ų50.15%0.04628%0.277CS..EExtended strand (participates in β ladder)trans-129.4141.7177.8-64.5170.2000107.9L112 I129 K133 K134 L136 V147 V151 A153L112-I131 HydrophobicContact CD2-CD1 3.72Å; I129-I131 HydrophobicContact CG2-CD1 3.74Å; I129-I131 HydrophobicContact CG2-CG1 3.76Å; I131-K133 PolarHBondContact O-N 3.2Å; I131-K133 VanDerWaalsContact O-N 3.14Å; I131-K134 PolarHBondContact N-O 3.44Å; I131-K134 PolarHBondContact O-N 3.15Å; I131-L136 HydrophobicContact CD1-CD1 4.33Å; I131-V147 HydrophobicContact CD1-CG2 4.44Å; I131-V147 HydrophobicContact CG2-CG1 4.48Å; I131-V147 HydrophobicContact CG2-CG2 3.9Å; I131-V151 HydrophobicContact CG2-CG1 4.04Å; I131-V151 HydrophobicContact CG2-CG2 3.76Å; I131-A153 HydrophobicContact CD1-CB 3.86Å; I131-A153 HydrophobicContact CG1-CB 3.6Å
132N79.9Confident81.3Confident71 Ų7146.8 Ų46.838%0.3824%0.242SC..THydrogen-bonded Turntrans50.541.3178.3-67.9-26.7000113.3K134 G146 V151N132-K134 PolarHBondContact O-N 3.38Å; N132-G146 VanDerWaalsContact ND2-C 3.28Å; N132-G146 PolarHBondContact ND2-O 3.47Å; N132-V151 WeakPolarHBondContact OD1-CG2 3.4Å
133K74.7Confident81.7Confident78 Ų7852.4 Ų52.434%0.33927%0.268SS..THydrogen-bonded Turntrans67.89.4178.4-38.3163.8175.8-156.90114.4I131 L300 D302I131-K133 PolarHBondContact O-N 3.2Å; I131-K133 VanDerWaalsContact O-N 3.14Å; K133-L300 HydrophobicContact CG-CD2 3.93Å; K133-D302 HydrophobicContact CD-CB 4.04Å; K133-D302 WeakPolarHBondContact CD-OD1 3.47Å; K133-D302 WeakPolarHBondContact CD-OD2 3.32Å; K133-D302 WeakPolarHBondContact CE-OD1 3.33Å; K133-D302 HydrophobicContact CG-CB 4Å; K133-D302 WeakPolarHBondContact CG-OD2 3.3Å; K133-D302 VanDerWaalsContact NZ-CG 3.32Å; K133-D302 IonicContact NZ-OD1 3.84Å; K133-D302 PolarHBondContact NZ-OD1 3.42Å; K133-D302 IonicContact NZ-OD2 2.61Å
134K81.5Confident82.4Confident148 Ų14855.6 Ų55.664%0.64328%0.283SS*.EExtended strand (participates in β ladder)trans-126148.3-179-65.7-179.3-178.9178.20110.1V130 I131 N132 L136V130-K134 WeakPolarHBondContact CA-O 3.43Å; I131-K134 PolarHBondContact N-O 3.44Å; I131-K134 PolarHBondContact O-N 3.15Å; N132-K134 PolarHBondContact O-N 3.38Å; K134-L136 PolarHBondContact O-N 3.16Å
135Q83.4Confident83Confident59 Ų5954.8 Ų54.828%0.27628%0.28SS..EExtended strand (participates in β ladder)trans-65.5132.6168.2-171.4-178.1-46.600109.3Q137Q135-Q137 PolarHBondContact O-N 3.36Å
136L87.3Confident83.6Confident12 Ų1253.3 Ų53.36%0.06328%0.283CS..PPolyproline II helixtrans-62.8127.2177.4-176.469.3000110.4L112 I129 I131 K134 L142L112-L136 HydrophobicContact CB-CD2 4.45Å; L112-L136 HydrophobicContact CD2-CD2 3.98Å; L112-L136 HydrophobicContact CG-CD2 4.48Å; I129-L136 HydrophobicContact CB-CB 4.04Å; I129-L136 HydrophobicContact CB-CD2 3.92Å; I129-L136 HydrophobicContact CD1-CD2 3.93Å; I129-L136 HydrophobicContact CG2-CB 4.21Å; I129-L136 HydrophobicContact CG2-CD2 3.97Å; I129-L136 VanDerWaalsContact O-CB 3.29Å; I129-L136 WeakPolarHBondContact O-CB 3.47Å; I129-L136 PolarHBondContact O-N 2.89Å; I131-L136 HydrophobicContact CD1-CD1 4.33Å; K134-L136 PolarHBondContact O-N 3.16Å; L136-L142 HydrophobicContact CD1-CD2 3.83Å
137Q84.3Confident84.3Confident84 Ų8453.1 Ų53.139%0.39328%0.283SS..PPolyproline II helixtrans-86.8120.8174.2-57.9-174.4-600109.2Q135 G139 Q145Q135-Q137 PolarHBondContact O-N 3.36Å; Q137-G139 VanDerWaalsContact C-N 3.3Å; Q137-G139 PolarHBondContact O-N 2.84Å; Q137-Q145 PolarHBondContact O-NE2 3Å
138L84.2Confident84.6Confident55 Ų5555.5 Ų55.529%0.28830%0.303SS..THydrogen-bonded Turntrans-68.8-27.4-173.3-58.3179.4000113.6R110 R113R110-L138 HydrophobicContact CB-CB 4.3Å; R110-L138 PolarHBondContact N-O 3.34Å; R113-L138 HydrophobicContact CB-CD2 4.4Å
139G81.3Confident84.8Confident73 Ų7355.8 Ų55.875%0.75331%0.305SS*.THydrogen-bonded Turntrans-90.7-4.5-175.500000115.6Q137Q137-G139 VanDerWaalsContact C-N 3.3Å; Q137-G139 PolarHBondContact O-N 2.84Å
140K87.7Confident84.6Confident93 Ų9357.9 Ų57.940%0.40432%0.316SS..SBendtrans-108.6157.8179.6-66.8-169.7-175.8167.90111.1T108 G109 Q145T108-K140 WeakPolarHBondContact CA-O 3.36Å; G109-K140 PolarHBondContact N-O 2.8Å; K140-Q145 HydrophobicContact CB-CG 3.99Å; K140-Q145 PolarHBondContact O-NE2 3.48Å; K140-Q145 VanDerWaalsContact O-NE2 3.15Å
141T90.2Very high84.7Confident31 Ų3158.3 Ų58.319%0.1932%0.319CS..BIsolated β-bridgetrans-68.9160.317363.10000110.9I107 E143 E144 Q145I107-T141 CarbonylContact O-C 3.28Å; I107-T141 VanDerWaalsContact O-CA 3.29Å; I107-T141 WeakPolarHBondContact O-CA 3.22Å; T141-E143 VanDerWaalsContact C-N 3.34Å; T141-E144 WeakPolarHBondContact OG1-CB 3.39Å; T141-E144 WeakPolarHBondContact OG1-CG 3.4Å; T141-E144 PolarHBondContact OG1-N 2.57Å; T141-E144 PolarHBondContact OG1-OE1 3.5Å; T141-Q145 WeakPolarHBondContact O-CG 3.12Å; T141-Q145 PolarHBondContact O-NE2 3.21Å
142L88.4Confident84.7Confident0 Ų060.8 Ų60.80%033%0.329CS..THydrogen-bonded Turntrans-67.3-38.3176.8-58.9-178.3000111.1I85 T103 L105 I107 L112 L136 Q145 G146 V147I85-L142 HydrophobicContact CD1-CD1 4.37Å; T103-L142 HydrophobicContact CG2-CD1 4.1Å; L105-L142 WeakPolarHBondContact O-CB 3.33Å; L105-L142 PolarHBondContact O-N 3.38Å; I107-L142 HydrophobicContact CD1-CD1 3.95Å; I107-L142 HydrophobicContact CG1-CD1 3.53Å; I107-L142 HydrophobicContact CG1-CG 3.9Å; I107-L142 PolarHBondContact O-N 2.83Å; L112-L142 HydrophobicContact CB-CD1 4.28Å; L112-L142 HydrophobicContact CB-CD2 4.05Å; L112-L142 HydrophobicContact CD1-CD1 4.48Å; L112-L142 HydrophobicContact CD2-CD1 3.9Å; L112-L142 HydrophobicContact CD2-CD2 3.52Å; L112-L142 HydrophobicContact CD2-CG 4.38Å; L112-L142 HydrophobicContact CG-CD1 4.45Å; L112-L142 HydrophobicContact CG-CD2 4.4Å; L136-L142 HydrophobicContact CD1-CD2 3.83Å; L142-Q145 CarbonylContact O-C 3.48Å; L142-Q145 PolarHBondContact O-N 3.36Å; L142-Q145 VanDerWaalsContact O-N 3.13Å; L142-G146 PolarHBondContact O-N 2.92Å; L142-V147 HydrophobicContact CB-CB 3.79Å; L142-V147 HydrophobicContact CB-CG1 4.09Å; L142-V147 HydrophobicContact CB-CG2 3.97Å; L142-V147 HydrophobicContact CD1-CG1 4.48Å; L142-V147 HydrophobicContact CD2-CG2 4.3Å; L142-V147 VanDerWaalsContact O-CB 3.24Å; L142-V147 WeakPolarHBondContact O-CB 3.27Å; L142-V147 VanDerWaalsContact O-CG2 3.25Å; L142-V147 WeakPolarHBondContact O-CG2 3.45Å; L142-V147 PolarHBondContact O-N 3.26Å
143E87.1Confident85Confident133 Ų13357.4 Ų57.462%0.62131%0.311SS*.G310 helixtrans-61-46.1177.6-173.8170.6-157.400112.8L105 T141 Q145 G146L105-E143 HydrophobicContact CB-CB 4.42Å; L105-E143 PolarHBondContact O-N 3.38Å; L105-E143 VanDerWaalsContact O-N 3.12Å; T141-E143 VanDerWaalsContact C-N 3.34Å; E143-Q145 PolarHBondContact O-N 2.92Å; E143-Q145 VanDerWaalsContact O-N 3.1Å; E143-G146 PolarHBondContact O-N 3.48Å
144E85.7Confident85.4Confident132 Ų13253.9 Ų53.962%0.61730%0.296SS*.G310 helixtrans-59.3-23.9175.2-77.6163.3-141.800113.4T141T141-E144 WeakPolarHBondContact OG1-CB 3.39Å; T141-E144 WeakPolarHBondContact OG1-CG 3.4Å; T141-E144 PolarHBondContact OG1-N 2.57Å; T141-E144 PolarHBondContact OG1-OE1 3.5Å
145Q87.6Confident85.6Confident44 Ų4446.9 Ų46.921%0.20627%0.265CS..G310 helixtrans-94.65.1180-63.4179.979.200112.4Q137 K140 T141 L142 E143 V147Q137-Q145 PolarHBondContact O-NE2 3Å; K140-Q145 HydrophobicContact CB-CG 3.99Å; K140-Q145 PolarHBondContact O-NE2 3.48Å; K140-Q145 VanDerWaalsContact O-NE2 3.15Å; T141-Q145 WeakPolarHBondContact O-CG 3.12Å; T141-Q145 PolarHBondContact O-NE2 3.21Å; L142-Q145 CarbonylContact O-C 3.48Å; L142-Q145 PolarHBondContact O-N 3.36Å; L142-Q145 VanDerWaalsContact O-N 3.13Å; E143-Q145 PolarHBondContact O-N 2.92Å; E143-Q145 VanDerWaalsContact O-N 3.1Å; Q145-V147 VanDerWaalsContact C-N 3.32Å; Q145-V147 HydrophobicContact CB-CG2 4.29Å
146G83.3Confident85.3Confident47 Ų4744.3 Ų44.349%0.48525%0.253SS..THydrogen-bonded Turntrans75.117.5178.200000114.1N132 L142 E143 A148N132-G146 VanDerWaalsContact ND2-C 3.28Å; N132-G146 PolarHBondContact ND2-O 3.47Å; L142-G146 PolarHBondContact O-N 2.92Å; E143-G146 PolarHBondContact O-N 3.48Å; G146-A148 PolarHBondContact O-N 2.9Å
147V85.7Confident84.8Confident6 Ų645.9 Ų45.94%0.03626%0.26CS..  trans-70.7120.4177.1-178.70000108.5I85 L105 I131 L142 Q145 V151I85-V147 HydrophobicContact CD1-CG1 4.33Å; L105-V147 HydrophobicContact CD2-CG1 4.27Å; I131-V147 HydrophobicContact CD1-CG2 4.44Å; I131-V147 HydrophobicContact CG2-CG1 4.48Å; I131-V147 HydrophobicContact CG2-CG2 3.9Å; L142-V147 HydrophobicContact CB-CB 3.79Å; L142-V147 HydrophobicContact CB-CG1 4.09Å; L142-V147 HydrophobicContact CB-CG2 3.97Å; L142-V147 HydrophobicContact CD1-CG1 4.48Å; L142-V147 HydrophobicContact CD2-CG2 4.3Å; L142-V147 VanDerWaalsContact O-CB 3.24Å; L142-V147 WeakPolarHBondContact O-CB 3.27Å; L142-V147 VanDerWaalsContact O-CG2 3.25Å; L142-V147 WeakPolarHBondContact O-CG2 3.45Å; L142-V147 PolarHBondContact O-N 3.26Å; Q145-V147 VanDerWaalsContact C-N 3.32Å; Q145-V147 HydrophobicContact CB-CG2 4.29Å; V147-V151 HydrophobicContact CG1-CG1 3.67Å
148A85.7Confident84Confident54 Ų5442.8 Ų42.845%0.44625%0.246SC..  trans-112.8172.3-179.600000111.8G146 V151G146-A148 PolarHBondContact O-N 2.9Å; A148-V151 WeakPolarHBondContact O-CB 3.35Å; A148-V151 WeakPolarHBondContact O-CG1 3.28Å; A148-V151 PolarHBondContact O-N 3.37Å
149H85.6Confident83Confident31 Ų3142.5 Ų42.514%0.14424%0.243CC..THydrogen-bonded Turntrans-59.9139.8171.7-179.572.6000111.5G73 N74 Y77 A83 T84 V151G73-H149 PolarHBondContact O-CE1 2.87Å; G73-H149 VanDerWaalsContact O-CE1 3.25Å; G73-H149 PolarHBondContact O-NE2 3.47Å; N74-H149 PolarHBondContact N-NE2 3.29Å; N74-H149 PolarHBondContact OD1-CD2 3.26Å; N74-H149 PolarHBondContact OD1-NE2 2.72Å; Y77-H149 HydrophobicContact CD1-CB 3.92Å; Y77-H149 AromaticContact CD1-CG 3.95Å; Y77-H149 HydrophobicContact CD2-CB 4.32Å; Y77-H149 HydrophobicContact CE1-CB 4Å; Y77-H149 HydrophobicContact CE2-CB 4.4Å; Y77-H149 HydrophobicContact CG-CB 4.08Å; Y77-H149 AromaticContact CG-CG 3.83Å; Y77-H149 AromaticContact CG-ND1 3.76Å; A83-H149 HydrophobicContact CB-CB 4.31Å; T84-H149 PolarHBondContact N-ND1 3.2Å; T84-H149 VanDerWaalsContact N-ND1 3.14Å; T84-H149 PolarHBondContact OG1-CE1 3.22Å; H149-V151 VanDerWaalsContact C-N 3.26Å; H149-V151 PolarHBondContact O-N 3.45Å
150N83.4Confident81.4Confident48 Ų4845 Ų4526%0.25724%0.235SC..THydrogen-bonded Turntrans61.225.8-175.9-62.2-38000115.1N74 T84N74-N150 PolarHBondContact OD1-ND2 2.87Å; T84-N150 VanDerWaalsContact O-CA 3.24Å; T84-N150 WeakPolarHBondContact O-CA 3.42Å; T84-N150 PolarHBondContact O-N 3.1Å
151V85.6Confident79.4Confident17 Ų1742.7 Ų42.710%0.10323%0.23CC..EExtended strand (participates in β ladder)trans-73.2150.4172.878.90000111.2I85 E86 I131 N132 V147 A148 H149I85-V151 HydrophobicContact CG1-CG1 4.27Å; I85-V151 HydrophobicContact CG2-CG1 4.21Å; E86-V151 PolarHBondContact N-O 3.5Å; I131-V151 HydrophobicContact CG2-CG1 4.04Å; I131-V151 HydrophobicContact CG2-CG2 3.76Å; N132-V151 WeakPolarHBondContact OD1-CG2 3.4Å; V147-V151 HydrophobicContact CG1-CG1 3.67Å; A148-V151 WeakPolarHBondContact O-CB 3.35Å; A148-V151 WeakPolarHBondContact O-CG1 3.28Å; A148-V151 PolarHBondContact O-N 3.37Å; H149-V151 VanDerWaalsContact C-N 3.26Å; H149-V151 PolarHBondContact O-N 3.45Å
152K86.2Confident76.9Confident61 Ų6149.6 Ų49.627%0.26526%0.26SS..EExtended strand (participates in β ladder)trans-89.9131.6173.6-57.9-179.8177.7169.10110.3E86 F88 E298E86-K152 HydrophobicContact CB-CG 4.5Å; E86-K152 CarbonylContact O-C 3.6Å; E86-K152 WeakPolarHBondContact O-CA 3.1Å; F88-K152 HydrophobicContact CD2-CB 4.14Å; F88-K152 HydrophobicContact CE2-CB 3.79Å; F88-K152 HydrophobicContact CE2-CD 3.72Å; F88-K152 HydrophobicContact CE2-CG 3.71Å; F88-K152 HydrophobicContact CZ-CD 4.09Å; F88-K152 HydrophobicContact CZ-CG 4.49Å; K152-E298 PolarHBondContact NZ-O 3.44Å
153A86.4Confident74.3Confident0 Ų059 Ų590%030%0.304CS..EExtended strand (participates in β ladder)trans-117.5114.3176.100000109.9I85 E86 V87 F88 I129 I131I85-A153 HydrophobicContact CG2-CB 3.57Å; E86-A153 PolarHBondContact O-N 2.88Å; V87-A153 CarbonylContact C-O 3.42Å; V87-A153 WeakPolarHBondContact CA-O 3.44Å; F88-A153 PolarHBondContact N-O 3.32Å; I129-A153 HydrophobicContact CG2-CB 4.29Å; I131-A153 HydrophobicContact CD1-CB 3.86Å; I131-A153 HydrophobicContact CG1-CB 3.6Å
154M83.3Confident71.9Confident4 Ų459.6 Ų59.62%0.0231%0.312CS..EExtended strand (participates in β ladder)trans-83.4122.2174161.9157.5-15800109.4I129 V130 L156 L256 Y291 L294 Q296 C299I129-M154 CarbonylContact C-O 3.52Å; I129-M154 WeakPolarHBondContact CA-O 3.31Å; V130-M154 HydrophobicContact CB-CB 4.15Å; V130-M154 HydrophobicContact CB-CG 4.33Å; V130-M154 PolarHBondContact N-O 2.92Å; V130-M154 PolarHBondContact O-N 3.01Å; M154-L156 HydrophobicContact CE-CD2 3.36Å; M154-L156 HydrophobicContact CG-CD2 3.97Å; M154-L156 HydrophobicContact CG-CG 4.28Å; M154-L156 HydrophobicContact SD-CD2 4.28Å; M154-L256 HydrophobicContact CE-CD2 3.88Å; M154-L256 HydrophobicContact SD-CD2 4.19Å; M154-Y291 HydrophobicContact CE-CD1 4.45Å; M154-Y291 HydrophobicContact SD-CD1 4.29Å; M154-Y291 HydrophobicContact SD-CE1 4.44Å; M154-L294 HydrophobicContact CE-CB 3.87Å; M154-L294 HydrophobicContact CE-CD1 3.6Å; M154-L294 HydrophobicContact CE-CG 4.37Å; M154-Q296 VanDerWaalsContact CB-OE1 3.32Å; M154-Q296 HydrophobicContact CE-CB 3.67Å; M154-Q296 VanDerWaalsContact CE-CD 3.48Å; M154-Q296 HydrophobicContact CE-CG 3.72Å; M154-Q296 VanDerWaalsContact CE-OE1 3.31Å; M154-Q296 HydrophobicContact SD-CB 4.03Å; M154-Q296 HydrophobicContact SD-CG 4.43Å; M154-Q296 PolarHBondContact SD-OE1 2.83Å; M154-C299 HydrophobicContact CB-CB 4.33Å; M154-C299 HydrophobicContact SD-CB 4.36Å
155V85.4Confident69.9Low0 Ų057.4 Ų57.40%032%0.317CS..EExtended strand (participates in β ladder)trans-99.4118174.6-177.50000108.4V87 F88 L89 P90 I116 L122 I127V87-V155 HydrophobicContact CG1-CG2 3.43Å; V87-V155 VanDerWaalsContact CG1-CG2 3.43Å; F88-V155 PolarHBondContact O-N 3.44Å; L89-V155 HydrophobicContact CD2-CB 4.4Å; L89-V155 HydrophobicContact CD2-CG2 4.38Å; P90-V155 WeakPolarHBondContact CD-O 3.44Å; I116-V155 HydrophobicContact CD1-CG2 4.47Å; I116-V155 HydrophobicContact CG2-CG2 3.85Å; L122-V155 HydrophobicContact CD1-CG1 3.95Å; I127-V155 HydrophobicContact CB-CG1 4.07Å; I127-V155 HydrophobicContact CG2-CG1 3.98Å
156L77.9Confident67.6Low5 Ų566.6 Ų66.63%0.02635%0.349CS..EExtended strand (participates in β ladder)trans-97.4116.8172.7-59177.9000108.1I127 K128 V130 M154 L256 P257 L294I127-L156 WeakPolarHBondContact CA-O 3.24Å; K128-L156 HydrophobicContact CB-CB 4.13Å; K128-L156 HydrophobicContact CB-CD1 4.44Å; K128-L156 PolarHBondContact N-O 3.49Å; K128-L156 PolarHBondContact O-N 3.12Å; V130-L156 HydrophobicContact CG2-CD1 3.87Å; V130-L156 HydrophobicContact CG2-CG 4.43Å; M154-L156 HydrophobicContact CE-CD2 3.36Å; M154-L156 HydrophobicContact CG-CD2 3.97Å; M154-L156 HydrophobicContact CG-CG 4.28Å; M154-L156 HydrophobicContact SD-CD2 4.28Å; L156-L256 HydrophobicContact CD1-CD2 3.95Å; L156-L256 HydrophobicContact CD1-CG 4.41Å; L156-L256 HydrophobicContact CD2-CD2 4.06Å; L156-P257 HydrophobicContact CD1-CG 4.03Å; L156-L294 HydrophobicContact CD2-CD1 3.72Å
157E75.9Confident65.5Low46 Ų4672.6 Ų72.622%0.21536%0.362CS..EExtended strand (participates in β ladder)trans-89.3123.3166.4-179.8174.5-15600108.3P90 K159P90-E157 HydrophobicContact CB-CB 4.25Å; P90-E157 HydrophobicContact CG-CB 3.48Å; P90-E157 VanDerWaalsContact CG-CB 3.48Å; E157-K159 HydrophobicContact CG-CB 4.13Å; E157-K159 PolarHBondContact O-N 3.27Å
158L67.9Low63.6Low18 Ų1879.8 Ų79.89%0.09440%0.4CS..  trans-81.712.7-175.2-60.2175000113.5Y126 K128 K182 G253 I254Y126-L158 PolarHBondContact O-N 2.76Å; K128-L158 HydrophobicContact CD-CD1 4.19Å; K128-L158 HydrophobicContact CD-CD2 4.31Å; K128-L158 HydrophobicContact CG-CD1 4.09Å; L158-K182 PolarHBondContact O-NZ 3.31Å; L158-G253 VanDerWaalsContact CD2-O 3.28Å; L158-G253 WeakPolarHBondContact CD2-O 3.47Å; L158-I254 HydrophobicContact CD2-CG1 4.16Å
159K63.7Low61.6Low50 Ų5085.5 Ų85.522%0.21742%0.415CS..  trans-96.8130.7173.8-69.2-173.8168.5-175.80111.1R92 Y126 E157 E175R92-K159 PolarHBondContact NH1-O 3.49Å; Y126-K159 HydrophobicContact CD1-CD 4.35Å; Y126-K159 HydrophobicContact CD1-CG 4.08Å; E157-K159 HydrophobicContact CG-CB 4.13Å; E157-K159 PolarHBondContact O-N 3.27Å; K159-E175 IonicContact NZ-OE1 3.24Å; K159-E175 IonicContact NZ-OE2 2.64Å; K159-E175 PolarHBondContact NZ-OE2 3.05Å
160Q46.8Very low59.9Low124 Ų12491.6 Ų91.658%0.57944%0.444SS*.  trans-95153.4154.8-66.8-168.2-1.700108.6K250Q160-K250 PolarHBondContact NE2-O 3.03Å
161S46.3Very low58.3Low45 Ų4593.3 Ų93.332%0.31545%0.452SS..  trans-129.9156.1-174.185.90000110.5R92R92-S161 PolarHBondContact NE-OG 3.11Å; R92-S161 PolarHBondContact NH2-OG 3.27Å
162E36Very low56.4Low176 Ų17697.2 Ų97.282%0.82247%0.47SS*.  -175.896.7101.9-93.1-172.7-179.800107.8
163E34Very low54.8Low198 Ų198100.7 Ų100.793%0.92549%0.487SS*.  trans-156.969.2147.7-111.6179.6-16100106A165E163-A165 PolarHBondContact O-N 2.91Å
164D36.9Very low53.2Low146 Ų146106.6 Ų106.678%0.78152%0.515SS*.  trans-63.1120.8176.6-83.9-22.7000109.6
165A44.4Very low51.5Low86 Ų86109 Ų10971%0.71153%0.526SS*.  trans75.189.5151.800000117.6E163E163-A165 PolarHBondContact O-N 2.91Å
166R39.4Very low49.8Very low236 Ų236112.7 Ų112.789%0.89154%0.543SS*.SBend-169.592.1119.3-97.9158.8-165.3-159.47.2112.5
167K39.2Very low48.8Very low174 Ų174116.9 Ų116.976%0.75757%0.565SS**  155.1119.4118.6-85.3174.3179.9178.10109.8
168N46.4Very low48Very low157 Ų157119 Ų11984%0.8458%0.575SS**  trans-65.2157.8-176.7-71.1-12.2000113.3
169F43.5Very low47.4Very low174 Ų174118.5 Ų118.576%0.76357%0.574SS**SBendtrans97.3-15.5162.7-120-89000119.4
170Q48.6Very low47.4Very low158 Ų158120.5 Ų120.574%0.73858%0.583SS**SBendtrans-105.4-32.6169.1-75.7174.5-14.500112.7E172 E173 E174Q170-E172 PolarHBondContact O-N 2.99Å; Q170-E173 PolarHBondContact O-N 3.4Å; Q170-E174 PolarHBondContact O-N 3.17Å
171L49.9Very low48.4Very low84 Ų84119.3 Ų119.344%0.4458%0.58SS.*Hα-helixtrans-65.5-33.6178.3-69.7168000113.1E173 E174 E175L171-E173 VanDerWaalsContact C-N 3.26Å; L171-E173 PolarHBondContact O-N 2.72Å; L171-E174 PolarHBondContact O-N 3.36Å; L171-E175 WeakPolarHBondContact O-CA 3.46Å; L171-E175 WeakPolarHBondContact O-CB 3.44Å; L171-E175 WeakPolarHBondContact O-CG 3Å; L171-E175 PolarHBondContact O-N 3.06Å
172E47.3Very low49.3Very low100 Ų100118.8 Ų118.847%0.46757%0.572SS.*Hα-helixtrans-65-30.3177.4-76.9-176.6164.600112.6Q170 Q176Q170-E172 PolarHBondContact O-N 2.99Å; E172-Q176 WeakPolarHBondContact O-CB 3.32Å; E172-Q176 WeakPolarHBondContact O-CG 3.35Å; E172-Q176 PolarHBondContact O-N 3.46Å
173E50.7Low50.8Low133 Ų133113.8 Ų113.862%0.62155%0.548SS*.Hα-helixtrans-80.9-41.5178.9-156.6174.6-165.300111.3Q170 L171 Q176 N177Q170-E173 PolarHBondContact O-N 3.4Å; L171-E173 VanDerWaalsContact C-N 3.26Å; L171-E173 PolarHBondContact O-N 2.72Å; E173-Q176 PolarHBondContact O-N 3.01Å; E173-N177 WeakPolarHBondContact O-CB 3.09Å; E173-N177 PolarHBondContact O-N 3.28Å; E173-N177 PolarHBondContact O-ND2 2.98Å; E173-N177 VanDerWaalsContact O-ND2 3.13Å
174E52.7Low52.6Low125 Ų125109.7 Ų109.758%0.58453%0.527SS*.Hα-helixtrans-62.8-44.1171.8-70.8178.5171.300111.7Q170 L171 N177 E178Q170-E174 PolarHBondContact O-N 3.17Å; L171-E174 PolarHBondContact O-N 3.36Å; E174-N177 WeakPolarHBondContact O-CB 3.37Å; E174-N177 PolarHBondContact O-N 3.01Å; E174-E178 WeakPolarHBondContact O-CB 3.09Å; E174-E178 PolarHBondContact O-N 3.42Å
175E49.5Very low54.4Low55 Ų55104.8 Ų104.826%0.25750%0.5SS..Hα-helixtrans-65.8-38.2174.8-71.4171.2-179.100111.3Y126 K159 L171 N177 E178 A179Y126-E175 WeakPolarHBondContact CE1-O 3.24Å; Y126-E175 PolarHBondContact OH-O 2.87Å; K159-E175 IonicContact NZ-OE1 3.24Å; K159-E175 IonicContact NZ-OE2 2.64Å; K159-E175 PolarHBondContact NZ-OE2 3.05Å; L171-E175 WeakPolarHBondContact O-CA 3.46Å; L171-E175 WeakPolarHBondContact O-CB 3.44Å; L171-E175 WeakPolarHBondContact O-CG 3Å; L171-E175 PolarHBondContact O-N 3.06Å; E175-N177 VanDerWaalsContact C-N 3.32Å; E175-E178 PolarHBondContact O-N 2.83Å; E175-A179 PolarHBondContact O-N 3.16Å
176Q49.4Very low55.7Low77 Ų77101.9 Ų101.936%0.3647%0.472SS..Hα-helixtrans-65.8-37.5174.6-82.8178.437.600111.8Y126 E172 E173 E178 K180Y126-Q176 WeakPolarHBondContact OH-CA 3.1Å; Y126-Q176 WeakPolarHBondContact OH-CG 3.44Å; Y126-Q176 PolarHBondContact OH-N 3.47Å; E172-Q176 WeakPolarHBondContact O-CB 3.32Å; E172-Q176 WeakPolarHBondContact O-CG 3.35Å; E172-Q176 PolarHBondContact O-N 3.46Å; E173-Q176 PolarHBondContact O-N 3.01Å; Q176-E178 VanDerWaalsContact C-N 3.34Å; Q176-K180 VanDerWaalsContact O-CB 3.3Å; Q176-K180 WeakPolarHBondContact O-CB 3.43Å; Q176-K180 WeakPolarHBondContact O-CD 3.31Å; Q176-K180 WeakPolarHBondContact O-CG 3.5Å; Q176-K180 PolarHBondContact O-N 3.39Å; Q176-K180 VanDerWaalsContact O-N 3.07Å
177N57.2Low57.4Low93 Ų9394.9 Ų94.950%0.49745%0.449SS..Hα-helixtrans-66.7-38.6173.3-70.6-26.1000111E173 E174 E175 K180 L181E173-N177 WeakPolarHBondContact O-CB 3.09Å; E173-N177 PolarHBondContact O-N 3.28Å; E173-N177 PolarHBondContact O-ND2 2.98Å; E173-N177 VanDerWaalsContact O-ND2 3.13Å; E174-N177 WeakPolarHBondContact O-CB 3.37Å; E174-N177 PolarHBondContact O-N 3.01Å; E175-N177 VanDerWaalsContact C-N 3.32Å; N177-K180 PolarHBondContact O-N 2.92Å; N177-L181 VanDerWaalsContact O-CB 3.24Å; N177-L181 WeakPolarHBondContact O-CB 3.34Å; N177-L181 PolarHBondContact O-N 3.25Å
178E57.6Low59.3Low89 Ų8990.7 Ų90.742%0.41643%0.429SS..Hα-helixtrans-69.3-41.9179.2-156.6-166.1149.300113.2E174 E175 Q176 L181 K182E174-E178 WeakPolarHBondContact O-CB 3.09Å; E174-E178 PolarHBondContact O-N 3.42Å; E175-E178 PolarHBondContact O-N 2.83Å; Q176-E178 VanDerWaalsContact C-N 3.34Å; E178-L181 WeakPolarHBondContact O-CB 3.41Å; E178-L181 PolarHBondContact O-N 3.46Å; E178-K182 WeakPolarHBondContact O-CG 3.39Å; E178-K182 PolarHBondContact O-N 3.05Å; E178-K182 VanDerWaalsContact OE1-CE 3.23Å; E178-K182 WeakPolarHBondContact OE1-CE 3.41Å; E178-K182 IonicContact OE1-NZ 2.81Å; E178-K182 PolarHBondContact OE1-NZ 2.86Å
179A56.7Low60.9Low8 Ų883.2 Ų83.27%0.06639%0.389CS..Hα-helixtrans-65.8-43.3172.500000112.9Y126 E175 L181 K182 E183Y126-A179 HydrophobicContact CD1-CB 3.26Å; Y126-A179 HydrophobicContact CD2-CB 4.27Å; Y126-A179 HydrophobicContact CE1-CB 3Å; Y126-A179 HydrophobicContact CE2-CB 4.07Å; Y126-A179 HydrophobicContact CG-CB 3.93Å; Y126-A179 VanDerWaalsContact CZ-CB 3.47Å; E175-A179 PolarHBondContact O-N 3.16Å; A179-L181 PolarHBondContact O-N 3.5Å; A179-K182 PolarHBondContact O-N 3.44Å; A179-E183 WeakPolarHBondContact O-CB 3.43Å; A179-E183 PolarHBondContact O-N 3.43Å
180K62.6Low62.6Low93 Ų9379.4 Ų79.440%0.40437%0.372SS..Hα-helixtrans-58.8-37.6173.6-75171.3-172.9167.40109.9Q176 N177 K184Q176-K180 VanDerWaalsContact O-CB 3.3Å; Q176-K180 WeakPolarHBondContact O-CB 3.43Å; Q176-K180 WeakPolarHBondContact O-CD 3.31Å; Q176-K180 WeakPolarHBondContact O-CG 3.5Å; Q176-K180 PolarHBondContact O-N 3.39Å; Q176-K180 VanDerWaalsContact O-N 3.07Å; N177-K180 PolarHBondContact O-N 2.92Å; K180-K184 WeakPolarHBondContact O-CB 3.34Å; K180-K184 WeakPolarHBondContact O-CD 3.34Å; K180-K184 WeakPolarHBondContact O-CG 3.46Å; K180-K184 PolarHBondContact O-N 2.95Å
181L67.2Low64.2Low99 Ų9979 Ų7952%0.51836%0.364SS..Hα-helixtrans-64.7-45.3176.2-16971000111.4N177 E178 A179 K184 Q185N177-L181 VanDerWaalsContact O-CB 3.24Å; N177-L181 WeakPolarHBondContact O-CB 3.34Å; N177-L181 PolarHBondContact O-N 3.25Å; E178-L181 WeakPolarHBondContact O-CB 3.41Å; E178-L181 PolarHBondContact O-N 3.46Å; A179-L181 PolarHBondContact O-N 3.5Å; L181-K184 CarbonylContact O-C 3.52Å; L181-K184 WeakPolarHBondContact O-CB 3.44Å; L181-K184 PolarHBondContact O-N 3.36Å; L181-Q185 WeakPolarHBondContact O-CB 3.12Å; L181-Q185 PolarHBondContact O-N 3.25Å
182K65.7Low65.8Low33 Ų3375 Ų7514%0.14334%0.343CS..Hα-helixtrans-68.6-40.6178.7-71.8172.5178173.80113L158 E178 A179 Q185 I186 I254L158-K182 PolarHBondContact O-NZ 3.31Å; E178-K182 WeakPolarHBondContact O-CG 3.39Å; E178-K182 PolarHBondContact O-N 3.05Å; E178-K182 VanDerWaalsContact OE1-CE 3.23Å; E178-K182 WeakPolarHBondContact OE1-CE 3.41Å; E178-K182 IonicContact OE1-NZ 2.81Å; E178-K182 PolarHBondContact OE1-NZ 2.86Å; A179-K182 PolarHBondContact O-N 3.44Å; K182-Q185 WeakPolarHBondContact O-CB 3.45Å; K182-Q185 PolarHBondContact O-N 3.06Å; K182-I186 WeakPolarHBondContact O-CD1 3.4Å; K182-I186 WeakPolarHBondContact O-CG1 3.4Å; K182-I186 PolarHBondContact O-N 3.44Å; K182-I254 HydrophobicContact CD-CD1 3.92Å; K182-I254 HydrophobicContact CG-CD1 4.12Å
183E67.4Low67.5Low72 Ų7270.6 Ų70.634%0.33632%0.322SS..Hα-helixtrans-64.6-43.3173.1-175.4172.9-165.600110.7A179 Q185 I186 Q187A179-E183 WeakPolarHBondContact O-CB 3.43Å; A179-E183 PolarHBondContact O-N 3.43Å; E183-Q185 VanDerWaalsContact C-N 3.29Å; E183-Q185 PolarHBondContact O-N 3.11Å; E183-I186 PolarHBondContact O-N 2.8Å; E183-Q187 WeakPolarHBondContact O-CB 3.16Å; E183-Q187 WeakPolarHBondContact O-CG 3.33Å; E183-Q187 PolarHBondContact O-N 3.07Å
184K72.1Confident69Low111 Ų11167 Ų6748%0.48331%0.306SS..Hα-helixtrans-59-40.8171-76.7171.3-177.6-176.10111.2K180 L181 Q187 R188K180-K184 WeakPolarHBondContact O-CB 3.34Å; K180-K184 WeakPolarHBondContact O-CD 3.34Å; K180-K184 WeakPolarHBondContact O-CG 3.46Å; K180-K184 PolarHBondContact O-N 2.95Å; L181-K184 CarbonylContact O-C 3.52Å; L181-K184 WeakPolarHBondContact O-CB 3.44Å; L181-K184 PolarHBondContact O-N 3.36Å; K184-Q187 CarbonylContact O-C 3.58Å; K184-Q187 PolarHBondContact O-N 2.92Å; K184-R188 VanDerWaalsContact O-CB 3.25Å; K184-R188 WeakPolarHBondContact O-CB 3.46Å; K184-R188 WeakPolarHBondContact O-CG 3.43Å; K184-R188 PolarHBondContact O-N 2.71Å
185Q74Confident70.4Confident43 Ų4362 Ų6220%0.20128%0.283CS..Hα-helixtrans-63-44.3178.9-169.7179.317.700111.7L181 K182 E183 Q187 R188 T189 E560L181-Q185 WeakPolarHBondContact O-CB 3.12Å; L181-Q185 PolarHBondContact O-N 3.25Å; K182-Q185 WeakPolarHBondContact O-CB 3.45Å; K182-Q185 PolarHBondContact O-N 3.06Å; E183-Q185 VanDerWaalsContact C-N 3.29Å; E183-Q185 PolarHBondContact O-N 3.11Å; Q185-Q187 PolarHBondContact O-N 3.34Å; Q185-R188 PolarHBondContact O-N 2.86Å; Q185-T189 WeakPolarHBondContact O-CB 3.45Å; Q185-T189 PolarHBondContact O-N 2.82Å; Q185-T189 PolarHBondContact O-OG1 3.43Å; Q185-E560 WeakPolarHBondContact CG-OE1 3.26Å; Q185-E560 PolarHBondContact NE2-OE1 3.45Å
186I71.9Confident71.7Confident25 Ų2559.9 Ų59.913%0.12827%0.273CS..Hα-helixtrans-63.8-42.8175.1-68.5154.9000110.8K182 E183 T189 K190 I254K182-I186 WeakPolarHBondContact O-CD1 3.4Å; K182-I186 WeakPolarHBondContact O-CG1 3.4Å; K182-I186 PolarHBondContact O-N 3.44Å; E183-I186 PolarHBondContact O-N 2.8Å; I186-T189 WeakPolarHBondContact O-CB 3.4Å; I186-K190 WeakPolarHBondContact O-CB 3.23Å; I186-K190 PolarHBondContact O-N 3.5Å; I186-I254 HydrophobicContact CD1-CG2 4.28Å; I186-I254 HydrophobicContact CG1-CG2 4.21Å
187Q76.2Confident73.1Confident89 Ų8956.2 Ų56.242%0.41626%0.256SS..Hα-helixtrans-67-38.2177.2-70.4-179.914.600112.2E183 K184 Q185 K190 R191E183-Q187 WeakPolarHBondContact O-CB 3.16Å; E183-Q187 WeakPolarHBondContact O-CG 3.33Å; E183-Q187 PolarHBondContact O-N 3.07Å; K184-Q187 CarbonylContact O-C 3.58Å; K184-Q187 PolarHBondContact O-N 2.92Å; Q185-Q187 PolarHBondContact O-N 3.34Å; Q187-K190 PolarHBondContact O-N 3.35Å; Q187-R191 WeakPolarHBondContact O-CG 3.48Å; Q187-R191 PolarHBondContact O-N 2.94Å
188R79.5Confident74Confident86 Ų8657 Ų5733%0.32526%0.255SS..Hα-helixtrans-64.3-48174.7-78.1170.2178.5175.7-6.7111K184 Q185 K190 R191 G192K184-R188 VanDerWaalsContact O-CB 3.25Å; K184-R188 WeakPolarHBondContact O-CB 3.46Å; K184-R188 WeakPolarHBondContact O-CG 3.43Å; K184-R188 PolarHBondContact O-N 2.71Å; Q185-R188 PolarHBondContact O-N 2.86Å; R188-K190 VanDerWaalsContact C-N 3.28Å; R188-K190 PolarHBondContact O-N 3.46Å; R188-R191 PolarHBondContact O-N 3.01Å; R188-R191 VanDerWaalsContact O-N 3.13Å; R188-G192 PolarHBondContact O-N 3.07Å
189T78.3Confident74.7Confident1 Ų155.6 Ų55.61%0.00625%0.246CC..Hα-helixtrans-52.2-49.6172.5-60.80000110.5Q185 I186 R191 G192 L193 Y239 K242Q185-T189 WeakPolarHBondContact O-CB 3.45Å; Q185-T189 PolarHBondContact O-N 2.82Å; Q185-T189 PolarHBondContact O-OG1 3.43Å; I186-T189 WeakPolarHBondContact O-CB 3.4Å; T189-R191 PolarHBondContact O-N 3.41Å; T189-G192 PolarHBondContact O-N 2.87Å; T189-L193 HydrophobicContact CG2-CD1 4Å; T189-L193 HydrophobicContact CG2-CG 4.48Å; T189-L193 WeakPolarHBondContact O-CB 3.46Å; T189-L193 WeakPolarHBondContact O-CG 3.46Å; T189-L193 PolarHBondContact O-N 3.3Å; T189-Y239 HydrophobicContact CG2-CE1 4.47Å; T189-K242 HydrophobicContact CG2-CB 4.26Å; T189-K242 HydrophobicContact CG2-CD 3.93Å; T189-K242 HydrophobicContact CG2-CG 3.67Å; T189-K242 VanDerWaalsContact OG1-CE 3.29Å; T189-K242 WeakPolarHBondContact OG1-CE 3.45Å
190K81Confident75Confident94 Ų9455.5 Ų55.541%0.40925%0.245SC..Hα-helixtrans-59.7-47.2178.5172.5164-177.5-176.80112.3I186 Q187 R188 L193 E194 Y239I186-K190 WeakPolarHBondContact O-CB 3.23Å; I186-K190 PolarHBondContact O-N 3.5Å; Q187-K190 PolarHBondContact O-N 3.35Å; R188-K190 VanDerWaalsContact C-N 3.28Å; R188-K190 PolarHBondContact O-N 3.46Å; K190-L193 PolarHBondContact O-N 3.09Å; K190-E194 WeakPolarHBondContact CE-OE1 3.36Å; K190-E194 WeakPolarHBondContact CG-OE1 3.11Å; K190-E194 WeakPolarHBondContact O-CB 3.07Å; K190-E194 VanDerWaalsContact O-CG 3.3Å; K190-E194 WeakPolarHBondContact O-CG 3.42Å; K190-E194 PolarHBondContact O-N 3.32Å; K190-Y239 VanDerWaalsContact CA-OH 3.31Å; K190-Y239 WeakPolarHBondContact CA-OH 3.24Å; K190-Y239 WeakPolarHBondContact CB-OH 3.46Å; K190-Y239 WeakPolarHBondContact CG-OH 3.38Å
191R82.1Confident74.9Confident149 Ų14954.2 Ų54.256%0.56225%0.252SS*.Hα-helixtrans-62.8-48.9178.2-73.5179-173.5178.72.2111.6Q187 R188 T189 L193 E194 I195Q187-R191 WeakPolarHBondContact O-CG 3.48Å; Q187-R191 PolarHBondContact O-N 2.94Å; R188-R191 PolarHBondContact O-N 3.01Å; R188-R191 VanDerWaalsContact O-N 3.13Å; T189-R191 PolarHBondContact O-N 3.41Å; R191-L193 VanDerWaalsContact C-N 3.31Å; R191-L193 PolarHBondContact O-N 3.45Å; R191-E194 PolarHBondContact O-N 3.33Å; R191-I195 WeakPolarHBondContact O-CB 3.35Å; R191-I195 WeakPolarHBondContact O-CD1 3.42Å; R191-I195 WeakPolarHBondContact O-CG1 3.47Å; R191-I195 PolarHBondContact O-N 2.95Å
192G82.9Confident74.5Confident0 Ų055.5 Ų55.50%026%0.255CS..Hα-helixtrans-60.6-39.7179.100000112.2R188 T189 I195 L196R188-G192 PolarHBondContact O-N 3.07Å; T189-G192 PolarHBondContact O-N 2.87Å; G192-I195 PolarHBondContact O-N 3.35Å; G192-L196 WeakPolarHBondContact O-CB 3.41Å; G192-L196 WeakPolarHBondContact O-CG 3.38Å; G192-L196 PolarHBondContact O-N 3.48Å
193L83.2Confident73.9Confident7 Ų757.6 Ų57.64%0.03727%0.271CS..Hα-helixtrans-67.4-40.9175.5-75.6177000111.8T189 K190 R191 I195 L196 A197 L235 Y239 I561T189-L193 HydrophobicContact CG2-CD1 4Å; T189-L193 HydrophobicContact CG2-CG 4.48Å; T189-L193 WeakPolarHBondContact O-CB 3.46Å; T189-L193 WeakPolarHBondContact O-CG 3.46Å; T189-L193 PolarHBondContact O-N 3.3Å; K190-L193 PolarHBondContact O-N 3.09Å; R191-L193 VanDerWaalsContact C-N 3.31Å; R191-L193 PolarHBondContact O-N 3.45Å; L193-I195 VanDerWaalsContact C-N 3.32Å; L193-I195 PolarHBondContact O-N 3.34Å; L193-L196 PolarHBondContact O-N 3.49Å; L193-A197 WeakPolarHBondContact O-CB 3.43Å; L193-A197 PolarHBondContact O-N 2.88Å; L193-L235 HydrophobicContact CB-CD2 3.91Å; L193-L235 WeakPolarHBondContact O-CD2 3.33Å; L193-Y239 HydrophobicContact CD1-CD1 3.61Å; L193-Y239 HydrophobicContact CD1-CD2 3.66Å; L193-Y239 HydrophobicContact CD1-CE1 3.73Å; L193-Y239 HydrophobicContact CD1-CE2 3.74Å; L193-Y239 HydrophobicContact CD1-CG 3.57Å; L193-I561 HydrophobicContact CB-CD1 4.34Å; L193-I561 HydrophobicContact CD2-CD1 4.05Å; L193-I561 HydrophobicContact CD2-CG2 3.83Å; L193-I561 HydrophobicContact CG-CD1 3.77Å; L193-I561 HydrophobicContact CG-CG1 4.47Å
194E82.6Confident73.1Confident59 Ų5958.2 Ų58.228%0.27628%0.28SS..Hα-helixtrans-64.2-37174.5-75.7175-17200112.3K190 R191 A197 K198 L235K190-E194 WeakPolarHBondContact CE-OE1 3.36Å; K190-E194 WeakPolarHBondContact CG-OE1 3.11Å; K190-E194 WeakPolarHBondContact O-CB 3.07Å; K190-E194 VanDerWaalsContact O-CG 3.3Å; K190-E194 WeakPolarHBondContact O-CG 3.42Å; K190-E194 PolarHBondContact O-N 3.32Å; R191-E194 PolarHBondContact O-N 3.33Å; E194-A197 WeakPolarHBondContact O-CB 3.24Å; E194-A197 PolarHBondContact O-N 3.11Å; E194-K198 VanDerWaalsContact O-CG 3.29Å; E194-K198 WeakPolarHBondContact O-CG 3.33Å; E194-K198 PolarHBondContact O-N 3.36Å; E194-L235 HydrophobicContact CG-CD2 4.45Å
195I80.8Confident71.9Confident18 Ų1856.4 Ų56.49%0.09228%0.278CS..Hα-helixtrans-67.1-48.8175.9-69.8160.6000110R191 G192 L193 A197 K198 R199 E554 V558R191-I195 WeakPolarHBondContact O-CB 3.35Å; R191-I195 WeakPolarHBondContact O-CD1 3.42Å; R191-I195 WeakPolarHBondContact O-CG1 3.47Å; R191-I195 PolarHBondContact O-N 2.95Å; G192-I195 PolarHBondContact O-N 3.35Å; L193-I195 VanDerWaalsContact C-N 3.32Å; L193-I195 PolarHBondContact O-N 3.34Å; I195-A197 VanDerWaalsContact C-N 3.27Å; I195-A197 PolarHBondContact O-N 3.39Å; I195-K198 PolarHBondContact O-N 3.25Å; I195-R199 HydrophobicContact CG2-CG 4.31Å; I195-R199 VanDerWaalsContact CG2-NH2 3.35Å; I195-R199 WeakPolarHBondContact O-CB 3.37Å; I195-R199 VanDerWaalsContact O-CG 3.3Å; I195-R199 WeakPolarHBondContact O-CG 3.35Å; I195-R199 PolarHBondContact O-N 3.08Å; I195-E554 HydrophobicContact CD1-CB 3.84Å; I195-E554 HydrophobicContact CD1-CG 3.6Å; I195-V558 HydrophobicContact CB-CG2 4.14Å; I195-V558 HydrophobicContact CG2-CG2 3.75Å
196L77.6Confident70.5Confident11 Ų1158.8 Ų58.86%0.05829%0.292CS..Hα-helixtrans-56.4-44.1173.2-75.1170.8000110.9G192 L193 K198 R199 A200 L213 M234 V558 I561G192-L196 WeakPolarHBondContact O-CB 3.41Å; G192-L196 WeakPolarHBondContact O-CG 3.38Å; G192-L196 PolarHBondContact O-N 3.48Å; L193-L196 PolarHBondContact O-N 3.49Å; L196-K198 PolarHBondContact O-N 3.13Å; L196-R199 PolarHBondContact O-N 2.99Å; L196-A200 WeakPolarHBondContact O-CB 3.11Å; L196-A200 PolarHBondContact O-N 2.64Å; L196-L213 HydrophobicContact CD1-CD1 4.05Å; L196-L213 HydrophobicContact CD2-CD1 4.39Å; L196-M234 WeakPolarHBondContact O-CE 3.44Å; L196-V558 HydrophobicContact CD1-CG1 4.42Å; L196-V558 HydrophobicContact CD2-CG1 3.72Å; L196-V558 HydrophobicContact CG-CG1 4.08Å; L196-V558 HydrophobicContact CG-CG2 4.24Å; L196-I561 HydrophobicContact CD1-CB 4.26Å; L196-I561 HydrophobicContact CD1-CD1 4.24Å; L196-I561 HydrophobicContact CD1-CG2 3.84Å
197A78.5Confident69.2Low1 Ų159.9 Ų59.91%0.00830%0.3CS..Hα-helixtrans-57.1-42.8174.700000114.7L193 E194 I195 A201 K231 M234 L235L193-A197 WeakPolarHBondContact O-CB 3.43Å; L193-A197 PolarHBondContact O-N 2.88Å; E194-A197 WeakPolarHBondContact O-CB 3.24Å; E194-A197 PolarHBondContact O-N 3.11Å; I195-A197 VanDerWaalsContact C-N 3.27Å; I195-A197 PolarHBondContact O-N 3.39Å; A197-A201 PolarHBondContact O-N 3.32Å; A197-K231 HydrophobicContact CB-CG 4.1Å; A197-M234 HydrophobicContact CB-CE 4.03Å; A197-L235 HydrophobicContact CB-CD2 3.82Å; A197-L235 HydrophobicContact CB-CG 3.96Å
198K76.3Confident67.7Low109 Ų10964.7 Ų64.747%0.47432%0.323SS..Hα-helixtrans-70.6-47174.9-70170.1-175.3177.80111.3E194 I195 L196 A200 A201 E202E194-K198 VanDerWaalsContact O-CG 3.29Å; E194-K198 WeakPolarHBondContact O-CG 3.33Å; E194-K198 PolarHBondContact O-N 3.36Å; I195-K198 PolarHBondContact O-N 3.25Å; L196-K198 PolarHBondContact O-N 3.13Å; K198-A200 VanDerWaalsContact C-N 3.31Å; K198-A200 PolarHBondContact O-N 3.49Å; K198-A201 CarbonylContact O-C 3.58Å; K198-A201 WeakPolarHBondContact O-CA 3.26Å; K198-A201 WeakPolarHBondContact O-CB 3.4Å; K198-A201 PolarHBondContact O-N 2.95Å; K198-E202 PolarHBondContact O-N 2.81Å
199R72.6Confident65.9Low60 Ų6068.3 Ų68.323%0.22635%0.345CS..Hα-helixtrans-61.6-34.1179-69.7177.7-173.4168.65.9112.8I195 L196 A201 E202 E554I195-R199 HydrophobicContact CG2-CG 4.31Å; I195-R199 VanDerWaalsContact CG2-NH2 3.35Å; I195-R199 WeakPolarHBondContact O-CB 3.37Å; I195-R199 VanDerWaalsContact O-CG 3.3Å; I195-R199 WeakPolarHBondContact O-CG 3.35Å; I195-R199 PolarHBondContact O-N 3.08Å; L196-R199 PolarHBondContact O-N 2.99Å; R199-A201 VanDerWaalsContact C-N 3.32Å; R199-E202 CarbonylContact O-C 3.6Å; R199-E202 VanDerWaalsContact O-C 3.28Å; R199-E202 PolarHBondContact O-N 3.33Å; R199-E554 IonicContact NH2-OE2 3.86Å
200A62.5Low64.5Low6 Ų669.5 Ų69.55%0.0535%0.353CS..Hα-helixtrans-75.9-21.4175.400000113.4L196 K198 Y212 M234L196-A200 WeakPolarHBondContact O-CB 3.11Å; L196-A200 PolarHBondContact O-N 2.64Å; K198-A200 VanDerWaalsContact C-N 3.31Å; K198-A200 PolarHBondContact O-N 3.49Å; A200-Y212 HydrophobicContact CB-CE2 4.43Å; A200-M234 HydrophobicContact CB-CE 3.31Å; A200-M234 HydrophobicContact CB-SD 3.73Å
201A59.9Low63.1Low66 Ų6668 Ų6855%0.54535%0.353SS..Hα-helixtrans-79.2-33.2169.200000111.6A197 K198 R199 T203A197-A201 PolarHBondContact O-N 3.32Å; K198-A201 CarbonylContact O-C 3.58Å; K198-A201 WeakPolarHBondContact O-CA 3.26Å; K198-A201 WeakPolarHBondContact O-CB 3.4Å; K198-A201 PolarHBondContact O-N 2.95Å; R199-A201 VanDerWaalsContact C-N 3.32Å; A201-T203 PolarHBondContact O-N 3.4Å
202E58.7Low61.9Low126 Ų12664.3 Ų64.359%0.58934%0.339SS*.SBendtrans-96.183.7178.3-66.8169.7-165.600110.1K198 R199 V204K198-E202 PolarHBondContact O-N 2.81Å; R199-E202 CarbonylContact O-C 3.6Å; R199-E202 VanDerWaalsContact O-C 3.28Å; R199-E202 PolarHBondContact O-N 3.33Å; E202-V204 PolarHBondContact O-N 2.86Å
203T53.3Low61.2Low76 Ų7667 Ų6747%0.46635%0.353SS..  trans-63.119.4-176.2-17.80000115.9A201A201-T203 PolarHBondContact O-N 3.4Å
204V50.5Low60.6Low86 Ų8670.1 Ų70.152%0.52137%0.37SS..  trans-12170.6-174-1700000109.6E202E202-V204 PolarHBondContact O-N 2.86Å
205V46.8Very low60.4Low73 Ų7368.4 Ų68.444%0.44236%0.362SS..SBendtrans-140.4145.5158.3-162.60000108.9T210V205-T210 HydrophobicContact CB-CG2 3.89Å; V205-T210 WeakPolarHBondContact CB-OG1 3.41Å; V205-T210 HydrophobicContact CG1-CG2 3.39Å; V205-T210 HydrophobicContact CG2-CG2 4.5Å
206D44.4Very low60.2Low93 Ų9369.1 Ų69.150%0.49737%0.371SS..  trans-51.3121.9-177.4-155-15.5000111.4E208 M209 T210D206-E208 PolarHBondContact O-N 3.36Å; D206-E208 VanDerWaalsContact O-N 3.14Å; D206-M209 HydrophobicContact CB-CB 4.49Å; D206-M209 PolarHBondContact O-N 2.86Å; D206-M209 VanDerWaalsContact O-N 3.14Å; D206-T210 PolarHBondContact O-N 2.98Å; D206-T210 VanDerWaalsContact O-N 3.12Å; D206-T210 PolarHBondContact O-OG1 3.18Å
207P45.4Very low60.3Low47 Ų4771.4 Ų71.431%0.30538%0.384SS..THydrogen-bonded Turntrans-59.8-22.3-176.1-24.931.9000115.5L433P207-L433 HydrophobicContact CG-CD1 3.48Å; P207-L433 VanDerWaalsContact CG-CD1 3.48Å; P207-L433 HydrophobicContact CG-CD2 4.34Å
208E44Very low60.1Low190 Ų19075.7 Ų75.789%0.88840%0.403SS*.THydrogen-bonded Turntrans-81.5-25.7179.6-72.6-175.4167.700112.7D206D206-E208 PolarHBondContact O-N 3.36Å; D206-E208 VanDerWaalsContact O-N 3.14Å
209M43Very low60Low162 Ų16272.7 Ų72.780%0.79839%0.394SS*.THydrogen-bonded Turntrans-103.1-15.7-177.6-89.8-82.3-172.300113.6D206D206-M209 HydrophobicContact CB-CB 4.49Å; D206-M209 PolarHBondContact O-N 2.86Å; D206-M209 VanDerWaalsContact O-N 3.14Å
210T47.7Very low60.1Low27 Ų2770.3 Ų70.317%0.16639%0.388CS..SBendtrans-126.6114.7-178.446.40000113.4V205 D206 Y212V205-T210 HydrophobicContact CB-CG2 3.89Å; V205-T210 WeakPolarHBondContact CB-OG1 3.41Å; V205-T210 HydrophobicContact CG1-CG2 3.39Å; V205-T210 HydrophobicContact CG2-CG2 4.5Å; D206-T210 PolarHBondContact O-N 2.98Å; D206-T210 VanDerWaalsContact O-N 3.12Å; D206-T210 PolarHBondContact O-OG1 3.18Å; T210-Y212 PolarHBondContact O-N 3.24Å; T210-Y212 VanDerWaalsContact O-N 3.14Å
211P51.7Low60.9Low63 Ų6376.2 Ų76.241%0.40941%0.409SS..  trans-66.3114.7171.323-27.5000109L562P211-L562 HydrophobicContact CB-CD1 3.92Å; P211-L562 HydrophobicContact CB-CD2 4.06Å; P211-L562 HydrophobicContact CG-CD1 3.17Å; P211-L562 HydrophobicContact CG-CD2 4.09Å; P211-L562 HydrophobicContact CG-CG 4.26Å
212Y57.7Low61.6Low71 Ų7175.2 Ų75.228%0.27840%0.398SS..  trans-94.3121.2179.6-171.4-105.3000109A200 T210 D214A200-Y212 HydrophobicContact CB-CE2 4.43Å; T210-Y212 PolarHBondContact O-N 3.24Å; T210-Y212 VanDerWaalsContact O-N 3.14Å; Y212-D214 WeakPolarHBondContact CD1-OD2 3.33Å; Y212-D214 WeakPolarHBondContact CE1-OD1 3.22Å; Y212-D214 VanDerWaalsContact CE1-OD2 3.29Å; Y212-D214 WeakPolarHBondContact CE1-OD2 3.45Å
213L67.9Low62.5Low56 Ų5672.3 Ų72.329%0.29339%0.386SS..  trans-90.3109.2175.3-72.4164.3000109.3L196 M234 I565L196-L213 HydrophobicContact CD1-CD1 4.05Å; L196-L213 HydrophobicContact CD2-CD1 4.39Å; L213-M234 HydrophobicContact CB-SD 4.28Å; L213-I565 HydrophobicContact CD1-CD1 3.66Å; L213-I565 HydrophobicContact CD2-CD1 3.77Å; L213-I565 HydrophobicContact CG-CD1 4.36Å
214D71.6Confident63.4Low72 Ų7276 Ų7639%0.38539%0.391SS..PPolyproline II helixtrans-94.5141.2170.2-95-45.3000110.2Y212Y212-D214 WeakPolarHBondContact CD1-OD2 3.33Å; Y212-D214 WeakPolarHBondContact CE1-OD1 3.22Å; Y212-D214 VanDerWaalsContact CE1-OD2 3.29Å; Y212-D214 WeakPolarHBondContact CE1-OD2 3.45Å
215I77.3Confident64.4Low23 Ų2372.5 Ų72.512%0.11837%0.37CS..PPolyproline II helixtrans-89.3120.8176-61167.7000108I223 I225 L233 M237I215-I223 HydrophobicContact CG2-CD1 4.17Å; I215-I223 HydrophobicContact CG2-CG1 4.13Å; I215-I223 WeakPolarHBondContact O-CG1 3.3Å; I215-I223 PolarHBondContact O-N 3.1Å; I215-I225 HydrophobicContact CB-CD1 3.5Å; I215-I225 VanDerWaalsContact CB-CD1 3.5Å; I215-I225 HydrophobicContact CD1-CD1 3.28Å; I215-I225 HydrophobicContact CG1-CD1 3.92Å; I215-I225 HydrophobicContact CG2-CD1 3.63Å; I215-L233 HydrophobicContact CD1-CD2 3.84Å; I215-L233 HydrophobicContact CD1-CG 4.14Å; I215-M237 HydrophobicContact CD1-SD 4.13Å; I215-M237 HydrophobicContact CG1-SD 4.13Å; I215-M237 HydrophobicContact CG2-CE 4.46Å; I215-M237 HydrophobicContact CG2-SD 4.21Å
216A77.6Confident65.6Low34 Ų3472.2 Ų72.228%0.28137%0.369SS..BIsolated β-bridgetrans-103157.817900000111.8R221A216-R221 CarbonylContact C-O 3.6Å; A216-R221 VanDerWaalsContact CA-O 3.28Å; A216-R221 WeakPolarHBondContact CA-O 3.33Å
217N78.6Confident66.8Low59 Ų5973.3 Ų73.332%0.31638%0.382SS..  trans-78.7177.1165.667.915.4000111.2T219 G220 R221 I223N217-T219 PolarHBondContact ND2-OG1 3.01Å; N217-T219 PolarHBondContact O-N 3.22Å; N217-T219 WeakPolarHBondContact OD1-CA 3.49Å; N217-T219 WeakPolarHBondContact OD1-CB 3.17Å; N217-T219 PolarHBondContact OD1-N 3.25Å; N217-T219 PolarHBondContact OD1-OG1 2.73Å; N217-G220 PolarHBondContact O-N 3.42Å; N217-G220 PolarHBondContact OD1-N 3.09Å; N217-R221 PolarHBondContact N-O 2.98Å; N217-R221 PolarHBondContact OD1-N 2.97Å; N217-R221 PolarHBondContact OD1-O 3.39Å; N217-I223 HydrophobicContact CB-CG2 3.79Å
218Q75.2Confident68Low90 Ų9076 Ų7642%0.42140%0.401SS..THydrogen-bonded Turntrans-57.2-5.7176.368.2-154.6-21.300116.7I328Q218-I328 HydrophobicContact CG-CG2 3.94Å; Q218-I328 VanDerWaalsContact NE2-CG2 3.32Å
219T73.5Confident69.6Low47 Ų4768.4 Ų68.429%0.28837%0.366SS..THydrogen-bonded Turntrans-102-8.2174.666.80000112.9N217 R414 I421N217-T219 PolarHBondContact ND2-OG1 3.01Å; N217-T219 PolarHBondContact O-N 3.22Å; N217-T219 WeakPolarHBondContact OD1-CA 3.49Å; N217-T219 WeakPolarHBondContact OD1-CB 3.17Å; N217-T219 PolarHBondContact OD1-N 3.25Å; N217-T219 PolarHBondContact OD1-OG1 2.73Å; T219-R414 PolarHBondContact O-NH2 3.33Å; T219-I421 WeakPolarHBondContact O-CD1 3.27Å
220G75.6Confident71.3Confident9 Ų964 Ų649%0.09334%0.34CS..SBendtrans91.710.1-174.600000114.3N217 I421 E569N217-G220 PolarHBondContact O-N 3.42Å; N217-G220 PolarHBondContact OD1-N 3.09Å; G220-I421 WeakPolarHBondContact O-CG2 3.17Å; G220-E569 WeakPolarHBondContact CA-OE1 3.42Å; G220-E569 WeakPolarHBondContact CA-OE2 3.4Å
221R77.5Confident72.9Confident130 Ų13067.9 Ų67.949%0.49136%0.355SS..  trans-94.8131.8179.9-66.6-175.3177.9-150.2-3.7111.4A216 N217 I223 I421A216-R221 CarbonylContact C-O 3.6Å; A216-R221 VanDerWaalsContact CA-O 3.28Å; A216-R221 WeakPolarHBondContact CA-O 3.33Å; N217-R221 PolarHBondContact N-O 2.98Å; N217-R221 PolarHBondContact OD1-N 2.97Å; N217-R221 PolarHBondContact OD1-O 3.39Å; R221-I223 PolarHBondContact O-N 3.32Å; R221-I421 HydrophobicContact CG-CG2 4.44Å
222S76.1Confident74.6Confident45 Ų4565.3 Ų65.332%0.31534%0.339SS..BIsolated β-bridgetrans-56.1131.2178.1-49.20000112.3E425S222-E425 WeakPolarHBondContact CB-OE2 3.21Å; S222-E425 PolarHBondContact OG-OE2 3.26Å
223I76.9Confident76Confident65 Ų6562.5 Ų62.533%0.33333%0.329SS..  trans-109.3148.2176.258.1164.5000111.9I215 N217 R221 I225I215-I223 HydrophobicContact CG2-CD1 4.17Å; I215-I223 HydrophobicContact CG2-CG1 4.13Å; I215-I223 WeakPolarHBondContact O-CG1 3.3Å; I215-I223 PolarHBondContact O-N 3.1Å; N217-I223 HydrophobicContact CB-CG2 3.79Å; R221-I223 PolarHBondContact O-N 3.32Å; I223-I225 HydrophobicContact CD1-CD1 4.22Å; I223-I225 HydrophobicContact CD1-CG1 4.05Å; I223-I225 HydrophobicContact CG1-CD1 4.21Å; I223-I225 HydrophobicContact CG1-CG1 4.19Å
224R71.4Confident76.7Confident153 Ų15360.8 Ų60.858%0.57732%0.32SS*.  trans-84.9118.4171.7-72.1-173173.5-149-14.4109.4
225I71.9Confident77.5Confident14 Ų1457.7 Ų57.77%0.07230%0.303CS..  trans-104.8138.7175.3-65.5150.1000108.5I215 I223 E229 R230 L233I215-I225 HydrophobicContact CB-CD1 3.5Å; I215-I225 VanDerWaalsContact CB-CD1 3.5Å; I215-I225 HydrophobicContact CD1-CD1 3.28Å; I215-I225 HydrophobicContact CG1-CD1 3.92Å; I215-I225 HydrophobicContact CG2-CD1 3.63Å; I223-I225 HydrophobicContact CD1-CD1 4.22Å; I223-I225 HydrophobicContact CD1-CG1 4.05Å; I223-I225 HydrophobicContact CG1-CD1 4.21Å; I223-I225 HydrophobicContact CG1-CG1 4.19Å; I225-E229 HydrophobicContact CG2-CB 4.4Å; I225-R230 HydrophobicContact CG2-CB 4.17Å; I225-L233 HydrophobicContact CD1-CD2 3.67Å; I225-L233 HydrophobicContact CG1-CD2 4.25Å; I225-L233 HydrophobicContact CG2-CD2 4.23Å
226P72.6Confident78.2Confident67 Ų6756.6 Ų56.644%0.43530%0.298SS..  trans-49.6134.1173.3-28.735.9000111.9S228 E229 R230P226-S228 PolarHBondContact O-N 3.02Å; P226-S228 VanDerWaalsContact O-N 3.1Å; P226-E229 PolarHBondContact O-N 2.89Å; P226-R230 PolarHBondContact O-N 3.45Å
227P69.5Low78.7Confident116 Ų11657.3 Ų57.375%0.75330%0.295SS*.Hα-helixtrans-56.7-30.1-179-25.433.3000113.5E229P227-E229 VanDerWaalsContact C-N 3.3Å; P227-E229 PolarHBondContact O-N 2.83Å
228S70.6Confident79.1Confident102 Ų10255 Ų5571%0.71329%0.286SS*.Hα-helixtrans-63-31.6177.549.10000113.6P226P226-S228 PolarHBondContact O-N 3.02Å; P226-S228 VanDerWaalsContact O-N 3.1Å
229E76.9Confident79.9Confident32 Ų3250.9 Ų50.915%0.1527%0.267CS..Hα-helixtrans-106.7-21.8-173.7-66.5-177.5-145.300112.8I225 P226 P227 K231 A232 L233 C270I225-E229 HydrophobicContact CG2-CB 4.4Å; P226-E229 PolarHBondContact O-N 2.89Å; P227-E229 VanDerWaalsContact C-N 3.3Å; P227-E229 PolarHBondContact O-N 2.83Å; E229-K231 VanDerWaalsContact C-N 3.26Å; E229-K231 PolarHBondContact O-N 3.39Å; E229-K231 VanDerWaalsContact O-N 3.15Å; E229-A232 PolarHBondContact O-N 3.36Å; E229-A232 VanDerWaalsContact O-N 3.13Å; E229-L233 WeakPolarHBondContact O-CB 3.5Å; E229-L233 PolarHBondContact O-N 3.49Å; E229-C270 VanDerWaalsContact CD-SG 3.57Å; E229-C270 VanDerWaalsContact OE1-CB 3.31Å; E229-C270 WeakPolarHBondContact OE1-CB 3.35Å; E229-C270 PolarHBondContact OE1-SG 2.95Å; E229-C270 PolarHBondContact OE2-N 3.44Å; E229-C270 PolarHBondContact OE2-SG 3.27Å
230R78.8Confident80.8Confident68 Ų6848.7 Ų48.726%0.25725%0.253SS..Hα-helixtrans-50.8-43.9-176.6176.7177.6-85.9-167.7-12.2113I225 P226 M234I225-R230 HydrophobicContact CG2-CB 4.17Å; P226-R230 PolarHBondContact O-N 3.45Å; R230-M234 WeakPolarHBondContact O-CB 3.28Å; R230-M234 PolarHBondContact O-N 3.41Å
231K82.2Confident81.6Confident109 Ų10949.8 Ų49.847%0.47426%0.255SS..Hα-helixtrans-64.8-49.4-179.1-172.4-176.4178179.10111.9A197 E229 L235A197-K231 HydrophobicContact CB-CG 4.1Å; E229-K231 VanDerWaalsContact C-N 3.26Å; E229-K231 PolarHBondContact O-N 3.39Å; E229-K231 VanDerWaalsContact O-N 3.15Å; K231-L235 HydrophobicContact CG-CD1 4.34Å; K231-L235 WeakPolarHBondContact O-CG 3.36Å; K231-L235 PolarHBondContact O-N 3.3Å; K231-L235 VanDerWaalsContact O-N 3.1Å
232A87.1Confident82.1Confident10 Ų1043.7 Ų43.78%0.08323%0.233CC..Hα-helixtrans-64-45.6-179.200000110.8E229 M234 L235 A236 E268E229-A232 PolarHBondContact O-N 3.36Å; E229-A232 VanDerWaalsContact O-N 3.13Å; A232-M234 PolarHBondContact O-N 2.87Å; A232-L235 PolarHBondContact O-N 3.35Å; A232-A236 WeakPolarHBondContact O-CB 3.49Å; A232-A236 PolarHBondContact O-N 2.92Å; A232-E268 HydrophobicContact CB-CB 4.12Å
233L86.6Confident82.8Confident12 Ų1241.5 Ų41.56%0.06322%0.218CC..Hα-helixtrans-61.5-43.7179.3-176.563.4000112.3I215 I225 E229 A236 M237 F266 L273I215-L233 HydrophobicContact CD1-CD2 3.84Å; I215-L233 HydrophobicContact CD1-CG 4.14Å; I225-L233 HydrophobicContact CD1-CD2 3.67Å; I225-L233 HydrophobicContact CG1-CD2 4.25Å; I225-L233 HydrophobicContact CG2-CD2 4.23Å; E229-L233 WeakPolarHBondContact O-CB 3.5Å; E229-L233 PolarHBondContact O-N 3.49Å; L233-A236 WeakPolarHBondContact O-CB 3.45Å; L233-A236 PolarHBondContact O-N 3.45Å; L233-M237 HydrophobicContact CD1-CG 4.4Å; L233-M237 HydrophobicContact CD1-SD 4.38Å; L233-M237 HydrophobicContact CG-SD 4.14Å; L233-M237 WeakPolarHBondContact O-CG 3.32Å; L233-M237 PolarHBondContact O-N 3.48Å; L233-F266 HydrophobicContact CD1-CD1 4.31Å; L233-F266 HydrophobicContact CD1-CE1 3.81Å; L233-L273 HydrophobicContact CD1-CD2 4.37Å; L233-L273 HydrophobicContact CD2-CD2 4.06Å
234M84.1Confident83.5Confident20 Ų2039.4 Ų39.410%0.09921%0.205CC..Hα-helixtrans-70.6-36.6-178.9-165.3170.361.800112.5L196 A197 A200 L213 R230 A232 A236 G238L196-M234 WeakPolarHBondContact O-CE 3.44Å; A197-M234 HydrophobicContact CB-CE 4.03Å; A200-M234 HydrophobicContact CB-CE 3.31Å; A200-M234 HydrophobicContact CB-SD 3.73Å; L213-M234 HydrophobicContact CB-SD 4.28Å; R230-M234 WeakPolarHBondContact O-CB 3.28Å; R230-M234 PolarHBondContact O-N 3.41Å; A232-M234 PolarHBondContact O-N 2.87Å; M234-A236 VanDerWaalsContact C-N 3.34Å; M234-G238 PolarHBondContact O-N 2.84Å
235L87.8Confident84.4Confident7 Ų732.7 Ų32.74%0.03718%0.182CC..Hα-helixtrans-60.5-46.5169.4-71.9173.1000110.4L193 E194 A197 K231 A232 M237 G238 Y239 Y265L193-L235 HydrophobicContact CB-CD2 3.91Å; L193-L235 WeakPolarHBondContact O-CD2 3.33Å; E194-L235 HydrophobicContact CG-CD2 4.45Å; A197-L235 HydrophobicContact CB-CD2 3.82Å; A197-L235 HydrophobicContact CB-CG 3.96Å; K231-L235 HydrophobicContact CG-CD1 4.34Å; K231-L235 WeakPolarHBondContact O-CG 3.36Å; K231-L235 PolarHBondContact O-N 3.3Å; K231-L235 VanDerWaalsContact O-N 3.1Å; A232-L235 PolarHBondContact O-N 3.35Å; L235-M237 PolarHBondContact O-N 3.14Å; L235-G238 PolarHBondContact O-N 3.14Å; L235-Y239 HydrophobicContact CB-CD2 4.48Å; L235-Y239 HydrophobicContact CD2-CE2 4.47Å; L235-Y239 WeakPolarHBondContact O-CB 3.47Å; L235-Y239 WeakPolarHBondContact O-CD2 3.45Å; L235-Y239 PolarHBondContact O-N 3.01Å; L235-Y265 HydrophobicContact CB-CD1 4.18Å; L235-Y265 HydrophobicContact CB-CD2 4.02Å; L235-Y265 HydrophobicContact CB-CE1 4.43Å; L235-Y265 HydrophobicContact CB-CE2 4.32Å; L235-Y265 HydrophobicContact CB-CG 3.97Å; L235-Y265 HydrophobicContact CD1-CD1 4.04Å; L235-Y265 HydrophobicContact CD1-CE1 3.64Å
236A90.8Very high85.2Confident0 Ų032 Ų320%018%0.179CC..Hα-helixtrans-59.1-48.818000000112.1A232 L233 M234 H240 A262 F266A232-A236 WeakPolarHBondContact O-CB 3.49Å; A232-A236 PolarHBondContact O-N 2.92Å; L233-A236 WeakPolarHBondContact O-CB 3.45Å; L233-A236 PolarHBondContact O-N 3.45Å; M234-A236 VanDerWaalsContact C-N 3.34Å; A236-H240 WeakPolarHBondContact O-CB 3.49Å; A236-H240 PolarHBondContact O-N 3.41Å; A236-A262 WeakPolarHBondContact O-CB 3.16Å; A236-F266 HydrophobicContact CB-CB 4.41Å; A236-F266 HydrophobicContact CB-CD1 3.92Å; A236-F266 HydrophobicContact CB-CD2 3.56Å; A236-F266 HydrophobicContact CB-CE1 4.02Å; A236-F266 HydrophobicContact CB-CE2 3.67Å; A236-F266 HydrophobicContact CB-CG 3.69Å; A236-F266 HydrophobicContact CB-CZ 3.9Å
237M88.6Confident86Confident48 Ų4829.7 Ų29.724%0.23616%0.163CC..Hα-helixtrans-62.6-46.3176.5-69.5177.471.400111.6I215 L233 L235 Y239 H240 E241 F266I215-M237 HydrophobicContact CD1-SD 4.13Å; I215-M237 HydrophobicContact CG1-SD 4.13Å; I215-M237 HydrophobicContact CG2-CE 4.46Å; I215-M237 HydrophobicContact CG2-SD 4.21Å; L233-M237 HydrophobicContact CD1-CG 4.4Å; L233-M237 HydrophobicContact CD1-SD 4.38Å; L233-M237 HydrophobicContact CG-SD 4.14Å; L233-M237 WeakPolarHBondContact O-CG 3.32Å; L233-M237 PolarHBondContact O-N 3.48Å; L235-M237 PolarHBondContact O-N 3.14Å; M237-Y239 PolarHBondContact O-N 3.11Å; M237-H240 WeakPolarHBondContact O-CB 3.44Å; M237-H240 PolarHBondContact O-N 3.27Å; M237-H240 VanDerWaalsContact O-N 3.15Å; M237-E241 WeakPolarHBondContact O-CG 3.37Å; M237-E241 PolarHBondContact O-N 2.86Å; M237-F266 HydrophobicContact CG-CZ 4.34Å
238G88.5Confident86.9Confident11 Ų1130.1 Ų30.111%0.11315%0.153CC..Hα-helixtrans-64.4-40.7-179.400000113.5M234 L235 H240 E241 K242M234-G238 PolarHBondContact O-N 2.84Å; L235-G238 PolarHBondContact O-N 3.14Å; G238-H240 VanDerWaalsContact C-N 3.33Å; G238-E241 PolarHBondContact O-N 2.82Å; G238-K242 WeakPolarHBondContact O-CB 3.24Å; G238-K242 PolarHBondContact O-N 3.19Å
239Y91.2Very high87.6Confident4 Ų431.1 Ų31.12%0.01614%0.141CC..Hα-helixtrans-66.2-35.9172.5-84.1-68.3000112.4T189 K190 L193 L235 M237 G243 C258 D261 Y265T189-Y239 HydrophobicContact CG2-CE1 4.47Å; K190-Y239 VanDerWaalsContact CA-OH 3.31Å; K190-Y239 WeakPolarHBondContact CA-OH 3.24Å; K190-Y239 WeakPolarHBondContact CB-OH 3.46Å; K190-Y239 WeakPolarHBondContact CG-OH 3.38Å; L193-Y239 HydrophobicContact CD1-CD1 3.61Å; L193-Y239 HydrophobicContact CD1-CD2 3.66Å; L193-Y239 HydrophobicContact CD1-CE1 3.73Å; L193-Y239 HydrophobicContact CD1-CE2 3.74Å; L193-Y239 HydrophobicContact CD1-CG 3.57Å; L235-Y239 HydrophobicContact CB-CD2 4.48Å; L235-Y239 HydrophobicContact CD2-CE2 4.47Å; L235-Y239 WeakPolarHBondContact O-CB 3.47Å; L235-Y239 WeakPolarHBondContact O-CD2 3.45Å; L235-Y239 PolarHBondContact O-N 3.01Å; M237-Y239 PolarHBondContact O-N 3.11Å; Y239-G243 PolarHBondContact O-N 3.27Å; Y239-C258 HydrophobicContact CD1-CB 4.5Å; Y239-D261 HydrophobicContact CD1-CB 4.08Å; Y239-D261 HydrophobicContact CD2-CB 4.38Å; Y239-D261 HydrophobicContact CE1-CB 4.19Å; Y239-D261 HydrophobicContact CG-CB 4.18Å; Y239-Y265 AromaticContact CD2-CD2 3.83Å; Y239-Y265 HydrophobicContact CD2-CD2 3.83Å; Y239-Y265 AromaticContact CD2-CE2 3.83Å; Y239-Y265 HydrophobicContact CD2-CE2 3.83Å; Y239-Y265 AromaticContact CE2-CD2 3.97Å; Y239-Y265 HydrophobicContact CE2-CD2 3.97Å; Y239-Y265 AromaticContact CE2-CE2 3.47Å; Y239-Y265 HydrophobicContact CE2-CE2 3.47Å; Y239-Y265 VanDerWaalsContact CE2-CE2 3.47Å
240H93.3Very high88.1Confident1 Ų134.6 Ų34.61%0.00516%0.156CC..Hα-helixtrans-64.8-47.6176.2-172.3-169.9000110.8A236 M237 G238 K242 G243 R244 A262 L283 D286A236-H240 WeakPolarHBondContact O-CB 3.49Å; A236-H240 PolarHBondContact O-N 3.41Å; M237-H240 WeakPolarHBondContact O-CB 3.44Å; M237-H240 PolarHBondContact O-N 3.27Å; M237-H240 VanDerWaalsContact O-N 3.15Å; G238-H240 VanDerWaalsContact C-N 3.33Å; H240-K242 PolarHBondContact O-N 2.98Å; H240-G243 CarbonylContact O-C 3.56Å; H240-G243 WeakPolarHBondContact O-CA 3.43Å; H240-G243 PolarHBondContact O-N 3.49Å; H240-R244 PolarHBondContact CE1-NH1 2.89Å; H240-R244 WeakPolarHBondContact O-CG 3.17Å; H240-R244 PolarHBondContact O-N 3.16Å; H240-A262 HydrophobicContact CB-CB 4.14Å; H240-L283 HydrophobicContact CB-CD1 4.43Å; H240-L283 PolarHBondContact CE1-N 3.23Å; H240-D286 IonicContact CD2-OD2 3.59Å; H240-D286 IonicContact CE1-OD2 3.76Å; H240-D286 IonicContact NE2-OD2 3.1Å; H240-D286 PolarHBondContact NE2-OD2 3.22Å
241E90.6Very high88.4Confident31 Ų3134.1 Ų34.115%0.14516%0.157CC..Hα-helixtrans-60.8-46.3176.1-62.9-52.5165.900112.4M237 G238 G243 R244 A245M237-E241 WeakPolarHBondContact O-CG 3.37Å; M237-E241 PolarHBondContact O-N 2.86Å; G238-E241 PolarHBondContact O-N 2.82Å; E241-G243 VanDerWaalsContact C-N 3.27Å; E241-G243 PolarHBondContact O-N 3.41Å; E241-R244 CarbonylContact O-C 3.53Å; E241-R244 WeakPolarHBondContact O-CA 3.37Å; E241-R244 WeakPolarHBondContact O-CB 3.27Å; E241-R244 PolarHBondContact O-N 2.9Å; E241-R244 IonicContact OE1-CZ 3.31Å; E241-R244 IonicContact OE1-NH2 3.01Å; E241-R244 PolarHBondContact OE1-NH2 2.79Å; E241-R244 IonicContact OE2-CZ 2.76Å; E241-R244 VanDerWaalsContact OE2-CZ 3.3Å; E241-R244 IonicContact OE2-NE 3.07Å; E241-R244 PolarHBondContact OE2-NE 3.36Å; E241-R244 IonicContact OE2-NH2 2.72Å; E241-R244 PolarHBondContact OE2-NH2 2.91Å; E241-A245 PolarHBondContact O-N 2.64Å
242K88.8Confident88.5Confident2 Ų230 Ų301%0.00914%0.138CC..Hα-helixtrans-58.5-43.3175.4-167.682.3177.6-178.80111.3T189 G238 H240 R244 A245 F246 E560 D564T189-K242 HydrophobicContact CG2-CB 4.26Å; T189-K242 HydrophobicContact CG2-CD 3.93Å; T189-K242 HydrophobicContact CG2-CG 3.67Å; T189-K242 VanDerWaalsContact OG1-CE 3.29Å; T189-K242 WeakPolarHBondContact OG1-CE 3.45Å; G238-K242 WeakPolarHBondContact O-CB 3.24Å; G238-K242 PolarHBondContact O-N 3.19Å; H240-K242 PolarHBondContact O-N 2.98Å; K242-R244 VanDerWaalsContact C-N 3.31Å; K242-R244 PolarHBondContact O-N 3.44Å; K242-A245 PolarHBondContact O-N 2.92Å; K242-F246 HydrophobicContact CD-CE2 4.33Å; K242-F246 HydrophobicContact CG-CD2 4.19Å; K242-F246 HydrophobicContact CG-CE2 3.69Å; K242-F246 WeakPolarHBondContact O-CD2 3.45Å; K242-F246 PolarHBondContact O-N 2.73Å; K242-F246 VanDerWaalsContact O-N 3.15Å; K242-E560 IonicContact NZ-OE1 2.72Å; K242-E560 PolarHBondContact NZ-OE1 3.45Å; K242-D564 HydrophobicContact CD-CB 4.22Å; K242-D564 WeakPolarHBondContact CD-OD2 3.32Å; K242-D564 WeakPolarHBondContact CE-OD2 3.38Å; K242-D564 IonicContact NZ-OD2 3.38Å; K242-D564 PolarHBondContact NZ-OD2 3.46Å
243G91.3Very high88.2Confident0 Ų030 Ų300%014%0.139CC..Hα-helixtrans-58-42.6174.100000112.3Y239 H240 E241 F246 L247Y239-G243 PolarHBondContact O-N 3.27Å; H240-G243 CarbonylContact O-C 3.56Å; H240-G243 WeakPolarHBondContact O-CA 3.43Å; H240-G243 PolarHBondContact O-N 3.49Å; E241-G243 VanDerWaalsContact C-N 3.27Å; E241-G243 PolarHBondContact O-N 3.41Å; G243-F246 PolarHBondContact O-N 3.36Å; G243-L247 WeakPolarHBondContact O-CG 3.28Å; G243-L247 PolarHBondContact O-N 2.8Å
244R91.4Very high87.9Confident20 Ų2029.7 Ų29.78%0.07514%0.138CC..Hα-helixtrans-66.4-38.7176.4-72.4-164.2-80.2-143.56.3113.2H240 E241 K242 F246 L247 K248H240-R244 PolarHBondContact CE1-NH1 2.89Å; H240-R244 WeakPolarHBondContact O-CG 3.17Å; H240-R244 PolarHBondContact O-N 3.16Å; E241-R244 CarbonylContact O-C 3.53Å; E241-R244 WeakPolarHBondContact O-CA 3.37Å; E241-R244 WeakPolarHBondContact O-CB 3.27Å; E241-R244 PolarHBondContact O-N 2.9Å; E241-R244 IonicContact OE1-CZ 3.31Å; E241-R244 IonicContact OE1-NH2 3.01Å; E241-R244 PolarHBondContact OE1-NH2 2.79Å; E241-R244 IonicContact OE2-CZ 2.76Å; E241-R244 VanDerWaalsContact OE2-CZ 3.3Å; E241-R244 IonicContact OE2-NE 3.07Å; E241-R244 PolarHBondContact OE2-NE 3.36Å; E241-R244 IonicContact OE2-NH2 2.72Å; E241-R244 PolarHBondContact OE2-NH2 2.91Å; K242-R244 VanDerWaalsContact C-N 3.31Å; K242-R244 PolarHBondContact O-N 3.44Å; R244-F246 VanDerWaalsContact C-N 3.3Å; R244-F246 PolarHBondContact O-N 3.39Å; R244-L247 WeakPolarHBondContact O-CB 3.17Å; R244-L247 PolarHBondContact O-N 2.87Å; R244-L247 VanDerWaalsContact O-N 3.12Å; R244-K248 PolarHBondContact O-N 3.48Å
245A89.4Confident88.2Confident12 Ų1228.8 Ų28.810%0.09913%0.133CC..Hα-helixtrans-58.1-44.617300000111E241 K242 K248 R249 D564E241-A245 PolarHBondContact O-N 2.64Å; K242-A245 PolarHBondContact O-N 2.92Å; A245-K248 PolarHBondContact O-N 3.34Å; A245-R249 WeakPolarHBondContact O-CG 3.2Å; A245-R249 PolarHBondContact O-N 2.89Å; A245-R249 VanDerWaalsContact O-N 3.15Å; A245-D564 HydrophobicContact CB-CB 3.86Å
246F88.3Confident88.3Confident1 Ų128.4 Ų28.40%0.00413%0.131CC..Hα-helixtrans-66.2-36.3173.4-68.8-57.4000113.3K242 G243 R244 R249 K250 E251 I254 A255K242-F246 HydrophobicContact CD-CE2 4.33Å; K242-F246 HydrophobicContact CG-CD2 4.19Å; K242-F246 HydrophobicContact CG-CE2 3.69Å; K242-F246 WeakPolarHBondContact O-CD2 3.45Å; K242-F246 PolarHBondContact O-N 2.73Å; K242-F246 VanDerWaalsContact O-N 3.15Å; G243-F246 PolarHBondContact O-N 3.36Å; R244-F246 VanDerWaalsContact C-N 3.3Å; R244-F246 PolarHBondContact O-N 3.39Å; F246-R249 CarbonylContact O-C 3.59Å; F246-R249 PolarHBondContact O-N 2.84Å; F246-K250 PolarHBondContact O-N 3.32Å; F246-K250 VanDerWaalsContact O-N 3.13Å; F246-E251 HydrophobicContact CB-CB 4.32Å; F246-E251 HydrophobicContact CD1-CB 4.29Å; F246-E251 WeakPolarHBondContact CD1-OE2 3.42Å; F246-E251 PolarHBondContact O-N 3.47Å; F246-I254 HydrophobicContact CD1-CB 4.4Å; F246-I254 HydrophobicContact CD1-CG2 4.19Å; F246-I254 HydrophobicContact CD2-CG2 3.96Å; F246-I254 HydrophobicContact CE1-CG2 3.96Å; F246-I254 HydrophobicContact CE2-CG2 3.7Å; F246-I254 HydrophobicContact CG-CB 4.42Å; F246-I254 HydrophobicContact CG-CG2 4.2Å; F246-I254 HydrophobicContact CZ-CG2 3.72Å; F246-A255 HydrophobicContact CB-CB 3.63Å
247L89.9Confident88.1Confident18 Ų1828.5 Ų28.59%0.09413%0.132CC..Hα-helixtrans-60-44.2173.2-72.7178.1000111.8G243 R244 R249 K250 Y252 A255 L259 D286 C290G243-L247 WeakPolarHBondContact O-CG 3.28Å; G243-L247 PolarHBondContact O-N 2.8Å; R244-L247 WeakPolarHBondContact O-CB 3.17Å; R244-L247 PolarHBondContact O-N 2.87Å; R244-L247 VanDerWaalsContact O-N 3.12Å; L247-R249 VanDerWaalsContact C-N 3.28Å; L247-R249 PolarHBondContact O-N 3.14Å; L247-K250 WeakPolarHBondContact O-CA 3.43Å; L247-K250 PolarHBondContact O-N 2.89Å; L247-Y252 HydrophobicContact CD2-CD1 3.68Å; L247-Y252 HydrophobicContact CD2-CE1 3.85Å; L247-A255 HydrophobicContact CD2-CB 3.98Å; L247-A255 HydrophobicContact CG-CB 4.14Å; L247-L259 HydrophobicContact CD1-CD1 4.19Å; L247-L259 HydrophobicContact CG-CD1 4.47Å; L247-D286 HydrophobicContact CD1-CB 3.86Å; L247-C290 WeakPolarHBondContact CD2-SG 3.42Å
248K88.2Confident88.1Confident125 Ų12526.3 Ų26.354%0.54312%0.121SC..Hα-helixtrans-61.1-37.5176.2-74.3177.5166.8-173.80111.9R244 A245 K250 D571R244-K248 PolarHBondContact O-N 3.48Å; A245-K248 PolarHBondContact O-N 3.34Å; K248-K250 PolarHBondContact O-N 2.66Å; K248-D571 IonicContact NZ-OD1 3.44Å; K248-D571 PolarHBondContact NZ-OD1 3.19Å; K248-D571 IonicContact NZ-OD2 2.8Å; K248-D571 PolarHBondContact NZ-OD2 2.84Å
249R86.5Confident88.3Confident122 Ų12225.8 Ų25.846%0.4612%0.116SC..THydrogen-bonded Turntrans-75.9-0.2173-63.3174.9-171.1146.19.7113.7A245 F246 L247 E251 D564A245-R249 WeakPolarHBondContact O-CG 3.2Å; A245-R249 PolarHBondContact O-N 2.89Å; A245-R249 VanDerWaalsContact O-N 3.15Å; F246-R249 CarbonylContact O-C 3.59Å; F246-R249 PolarHBondContact O-N 2.84Å; L247-R249 VanDerWaalsContact C-N 3.28Å; L247-R249 PolarHBondContact O-N 3.14Å; R249-E251 HydrophobicContact CB-CG 4.1Å; R249-E251 PolarHBondContact O-N 3.36Å; R249-D564 IonicContact CZ-OD1 2.78Å; R249-D564 IonicContact NH1-OD1 3.46Å; R249-D564 IonicContact NH2-OD1 3.83Å; R249-D564 PolarHBondContact NH2-OD1 3.47Å
250K86.8Confident88.3Confident106 Ų10626 Ų2646%0.46112%0.117SC..THydrogen-bonded Turntrans6022.1-174.9-56.3-176.5175.81800113.6Q160 F246 L247 K248 Y252Q160-K250 PolarHBondContact NE2-O 3.03Å; F246-K250 PolarHBondContact O-N 3.32Å; F246-K250 VanDerWaalsContact O-N 3.13Å; L247-K250 WeakPolarHBondContact O-CA 3.43Å; L247-K250 PolarHBondContact O-N 2.89Å; K248-K250 PolarHBondContact O-N 2.66Å; K250-Y252 VanDerWaalsContact C-N 3.3Å; K250-Y252 HydrophobicContact CB-CE2 3.88Å; K250-Y252 WeakPolarHBondContact O-CD2 3.47Å; K250-Y252 VanDerWaalsContact O-CE2 3.31Å; K250-Y252 WeakPolarHBondContact O-CE2 3.04Å; K250-Y252 PolarHBondContact O-N 3.03Å; K250-Y252 VanDerWaalsContact O-N 3.11Å
251E84.3Confident88.1Confident58 Ų5827.9 Ų27.927%0.27113%0.127SC..  trans-87.558.9179.9-68.9179.9-162.700112.1F246 R249 G253 I254 A255F246-E251 HydrophobicContact CB-CB 4.32Å; F246-E251 HydrophobicContact CD1-CB 4.29Å; F246-E251 WeakPolarHBondContact CD1-OE2 3.42Å; F246-E251 PolarHBondContact O-N 3.47Å; R249-E251 HydrophobicContact CB-CG 4.1Å; R249-E251 PolarHBondContact O-N 3.36Å; E251-G253 PolarHBondContact O-N 3.12Å; E251-G253 VanDerWaalsContact O-N 3.11Å; E251-I254 PolarHBondContact O-N 3.45Å; E251-A255 PolarHBondContact O-N 3.2Å
252Y85.7Confident88.2Confident21 Ų2126.4 Ų26.48%0.08212%0.12CC..Hα-helixtrans-57.5-32.1-171.2-55.3-67.9000114.6L247 K250 I254 L256 R293L247-Y252 HydrophobicContact CD2-CD1 3.68Å; L247-Y252 HydrophobicContact CD2-CE1 3.85Å; K250-Y252 VanDerWaalsContact C-N 3.3Å; K250-Y252 HydrophobicContact CB-CE2 3.88Å; K250-Y252 WeakPolarHBondContact O-CD2 3.47Å; K250-Y252 VanDerWaalsContact O-CE2 3.31Å; K250-Y252 WeakPolarHBondContact O-CE2 3.04Å; K250-Y252 PolarHBondContact O-N 3.03Å; K250-Y252 VanDerWaalsContact O-N 3.11Å; Y252-I254 VanDerWaalsContact C-N 3.33Å; Y252-I254 PolarHBondContact O-N 2.9Å; Y252-L256 WeakPolarHBondContact O-CB 3.45Å; Y252-L256 PolarHBondContact O-N 3.31Å; Y252-L256 VanDerWaalsContact O-N 3.07Å; Y252-R293 HydrophobicContact CD1-CB 3.78Å; Y252-R293 HydrophobicContact CD1-CG 4.08Å; Y252-R293 HydrophobicContact CD2-CB 3.71Å; Y252-R293 HydrophobicContact CD2-CG 4.45Å; Y252-R293 HydrophobicContact CE1-CB 3.88Å; Y252-R293 HydrophobicContact CE1-CG 3.7Å; Y252-R293 HydrophobicContact CE2-CB 3.81Å; Y252-R293 HydrophobicContact CE2-CG 4.1Å; Y252-R293 HydrophobicContact CG-CB 3.71Å; Y252-R293 HydrophobicContact CG-CG 4.46Å; Y252-R293 PolarHBondContact OH-NE 2.86Å; Y252-R293 PolarHBondContact OH-NH1 2.78Å; Y252-R293 PolarHBondContact OH-NH2 2.86Å; Y252-R293 VanDerWaalsContact OH-NH2 3.07Å
253G79.8Confident88.4Confident11 Ų1127.1 Ų27.111%0.11312%0.124CC..Hα-helixtrans-66.7-31.2179.100000113.8L158 E251 P257L158-G253 VanDerWaalsContact CD2-O 3.28Å; L158-G253 WeakPolarHBondContact CD2-O 3.47Å; E251-G253 PolarHBondContact O-N 3.12Å; E251-G253 VanDerWaalsContact O-N 3.11Å; G253-P257 WeakPolarHBondContact O-CD 3.41Å; G253-P257 WeakPolarHBondContact O-CG 3.34Å
254I81.9Confident88.4Confident6 Ų631.5 Ų31.53%0.03114%0.143CC..Hα-helixtrans-90.4-37.8176.7-53.5177.8000110.2L158 K182 I186 F246 E251 Y252 L256 P257L158-I254 HydrophobicContact CD2-CG1 4.16Å; K182-I254 HydrophobicContact CD-CD1 3.92Å; K182-I254 HydrophobicContact CG-CD1 4.12Å; I186-I254 HydrophobicContact CD1-CG2 4.28Å; I186-I254 HydrophobicContact CG1-CG2 4.21Å; F246-I254 HydrophobicContact CD1-CB 4.4Å; F246-I254 HydrophobicContact CD1-CG2 4.19Å; F246-I254 HydrophobicContact CD2-CG2 3.96Å; F246-I254 HydrophobicContact CE1-CG2 3.96Å; F246-I254 HydrophobicContact CE2-CG2 3.7Å; F246-I254 HydrophobicContact CG-CB 4.42Å; F246-I254 HydrophobicContact CG-CG2 4.2Å; F246-I254 HydrophobicContact CZ-CG2 3.72Å; E251-I254 PolarHBondContact O-N 3.45Å; Y252-I254 VanDerWaalsContact C-N 3.33Å; Y252-I254 PolarHBondContact O-N 2.9Å; I254-L256 PolarHBondContact O-N 3.14Å; I254-P257 VanDerWaalsContact O-CD 3.3Å; I254-P257 WeakPolarHBondContact O-CD 3.33Å
255A89.9Confident88.3Confident0 Ų031.9 Ų31.90%015%0.145CC..Hα-helixtrans-57.2-49.2177.600000112.2F246 L247 E251 C258 L259F246-A255 HydrophobicContact CB-CB 3.63Å; L247-A255 HydrophobicContact CD2-CB 3.98Å; L247-A255 HydrophobicContact CG-CB 4.14Å; E251-A255 PolarHBondContact O-N 3.2Å; A255-C258 WeakPolarHBondContact O-CB 3.47Å; A255-C258 PolarHBondContact O-N 3Å; A255-C258 VanDerWaalsContact O-N 3.09Å; A255-L259 VanDerWaalsContact O-CG 3.32Å; A255-L259 WeakPolarHBondContact O-CG 3.39Å; A255-L259 PolarHBondContact O-N 3.19Å
256L88.4Confident88.4Confident0 Ų031.3 Ų31.30%014%0.14CC..Hα-helixtrans-57.7-48-173.8174.862.7000113.4M154 L156 Y252 I254 C258 L259 L260 I287 C290 Y291 L294M154-L256 HydrophobicContact CE-CD2 3.88Å; M154-L256 HydrophobicContact SD-CD2 4.19Å; L156-L256 HydrophobicContact CD1-CD2 3.95Å; L156-L256 HydrophobicContact CD1-CG 4.41Å; L156-L256 HydrophobicContact CD2-CD2 4.06Å; Y252-L256 WeakPolarHBondContact O-CB 3.45Å; Y252-L256 PolarHBondContact O-N 3.31Å; Y252-L256 VanDerWaalsContact O-N 3.07Å; I254-L256 PolarHBondContact O-N 3.14Å; L256-C258 PolarHBondContact O-N 3.41Å; L256-L259 PolarHBondContact O-N 3.05Å; L256-L260 HydrophobicContact CD1-CD1 4.12Å; L256-L260 HydrophobicContact CD1-CD2 4.37Å; L256-L260 HydrophobicContact CD1-CG 3.94Å; L256-L260 HydrophobicContact CG-CD1 4.18Å; L256-L260 HydrophobicContact CG-CG 4.41Å; L256-L260 WeakPolarHBondContact O-CG 3.4Å; L256-L260 PolarHBondContact O-N 3.05Å; L256-I287 HydrophobicContact CD1-CG2 4.17Å; L256-C290 HydrophobicContact CB-CB 4.13Å; L256-C290 HydrophobicContact CD1-CB 4.05Å; L256-Y291 HydrophobicContact CD1-CD1 4.1Å; L256-Y291 HydrophobicContact CD1-CE1 3.41Å; L256-Y291 VanDerWaalsContact CD1-CE1 3.41Å; L256-Y291 HydrophobicContact CD2-CD1 3.93Å; L256-Y291 HydrophobicContact CD2-CE1 3.62Å; L256-Y291 HydrophobicContact CG-CE1 4.15Å; L256-L294 HydrophobicContact CB-CD1 4.36Å; L256-L294 HydrophobicContact CD2-CD1 3.75Å
257P86.4Confident88.4Confident1 Ų135 Ų351%0.00617%0.165CC..Hα-helixtrans-50.1-48.8170.5-31.834.9000114.7K128 L156 G253 I254 L259 L260 D261K128-P257 HydrophobicContact CD-CB 4.14Å; K128-P257 HydrophobicContact CD-CG 3.59Å; K128-P257 VanDerWaalsContact NZ-CB 3.31Å; L156-P257 HydrophobicContact CD1-CG 4.03Å; G253-P257 WeakPolarHBondContact O-CD 3.41Å; G253-P257 WeakPolarHBondContact O-CG 3.34Å; I254-P257 VanDerWaalsContact O-CD 3.3Å; I254-P257 WeakPolarHBondContact O-CD 3.33Å; P257-L259 PolarHBondContact O-N 2.91Å; P257-L260 PolarHBondContact O-N 3.28Å; P257-D261 PolarHBondContact O-N 2.95Å
258C89.8Confident88.3Confident2 Ų239.3 Ų39.31%0.01419%0.185CC..Hα-helixtrans-62.2-42.8178.9-65.80000111.5Y239 A255 L256 L260 D261 A262Y239-C258 HydrophobicContact CD1-CB 4.5Å; A255-C258 WeakPolarHBondContact O-CB 3.47Å; A255-C258 PolarHBondContact O-N 3Å; A255-C258 VanDerWaalsContact O-N 3.09Å; L256-C258 PolarHBondContact O-N 3.41Å; C258-L260 VanDerWaalsContact C-N 3.34Å; C258-L260 PolarHBondContact O-N 3.39Å; C258-D261 PolarHBondContact O-N 2.87Å; C258-A262 PolarHBondContact O-N 3.32Å
259L92.7Very high88.2Confident0 Ų033.8 Ų33.80%016%0.162CC..Hα-helixtrans-66-35177.8-61.2170.7000112.4L247 A255 L256 P257 A262 D263 L283 D286 I287L247-L259 HydrophobicContact CD1-CD1 4.19Å; L247-L259 HydrophobicContact CG-CD1 4.47Å; A255-L259 VanDerWaalsContact O-CG 3.32Å; A255-L259 WeakPolarHBondContact O-CG 3.39Å; A255-L259 PolarHBondContact O-N 3.19Å; L256-L259 PolarHBondContact O-N 3.05Å; P257-L259 PolarHBondContact O-N 2.91Å; L259-A262 WeakPolarHBondContact O-CB 3.27Å; L259-A262 PolarHBondContact O-N 3.5Å; L259-D263 PolarHBondContact O-N 3.04Å; L259-L283 HydrophobicContact CB-CD1 3.93Å; L259-L283 HydrophobicContact CD2-CD1 3.67Å; L259-L283 HydrophobicContact CG-CD1 4.39Å; L259-D286 HydrophobicContact CD1-CB 4.17Å; L259-D286 HydrophobicContact CD2-CB 4.29Å; L259-I287 HydrophobicContact CB-CD1 4.41Å; L259-I287 HydrophobicContact CB-CG1 3.64Å; L259-I287 HydrophobicContact CD1-CG1 4.41Å
260L90.9Very high88Confident9 Ų930 Ų305%0.04715%0.154CC..Hα-helixtrans-70.4-36175.1-70.3179.1000112.5V130 L256 P257 C258 A262 D263 K264 I287V130-L260 HydrophobicContact CG1-CD1 3.75Å; V130-L260 HydrophobicContact CG2-CD1 4.02Å; L256-L260 HydrophobicContact CD1-CD1 4.12Å; L256-L260 HydrophobicContact CD1-CD2 4.37Å; L256-L260 HydrophobicContact CD1-CG 3.94Å; L256-L260 HydrophobicContact CG-CD1 4.18Å; L256-L260 HydrophobicContact CG-CG 4.41Å; L256-L260 WeakPolarHBondContact O-CG 3.4Å; L256-L260 PolarHBondContact O-N 3.05Å; P257-L260 PolarHBondContact O-N 3.28Å; C258-L260 VanDerWaalsContact C-N 3.34Å; C258-L260 PolarHBondContact O-N 3.39Å; L260-A262 VanDerWaalsContact C-N 3.35Å; L260-D263 PolarHBondContact O-N 2.65Å; L260-K264 PolarHBondContact O-N 3.25Å; L260-K264 VanDerWaalsContact O-N 3.1Å; L260-I287 HydrophobicContact CD2-CD1 4.46Å; L260-I287 HydrophobicContact CD2-CG2 4.34Å
261D89.6Confident87.7Confident40 Ų4034.9 Ų34.921%0.21417%0.169CC..Hα-helixtrans-64.9-41.3171.3-78-30000110.6Y239 P257 C258 D263 K264 Y265Y239-D261 HydrophobicContact CD1-CB 4.08Å; Y239-D261 HydrophobicContact CD2-CB 4.38Å; Y239-D261 HydrophobicContact CE1-CB 4.19Å; Y239-D261 HydrophobicContact CG-CB 4.18Å; P257-D261 PolarHBondContact O-N 2.95Å; C258-D261 PolarHBondContact O-N 2.87Å; D261-D263 PolarHBondContact O-N 3.1Å; D261-K264 WeakPolarHBondContact O-CB 3.48Å; D261-K264 PolarHBondContact O-N 3.05Å; D261-Y265 WeakPolarHBondContact O-CD2 3.49Å; D261-Y265 PolarHBondContact O-N 3.18Å; D261-Y265 VanDerWaalsContact O-N 3.14Å
262A93.2Very high87.4Confident0 Ų039.8 Ų39.80%019%0.192CC..Hα-helixtrans-57.5-46171.900000112.1A236 H240 C258 L259 L260 K264 Y265 F266 L283A236-A262 WeakPolarHBondContact O-CB 3.16Å; H240-A262 HydrophobicContact CB-CB 4.14Å; C258-A262 PolarHBondContact O-N 3.32Å; L259-A262 WeakPolarHBondContact O-CB 3.27Å; L259-A262 PolarHBondContact O-N 3.5Å; L260-A262 VanDerWaalsContact C-N 3.35Å; A262-K264 VanDerWaalsContact C-N 3.28Å; A262-K264 PolarHBondContact O-N 3.05Å; A262-Y265 PolarHBondContact O-N 3.41Å; A262-Y265 VanDerWaalsContact O-N 3.15Å; A262-F266 VanDerWaalsContact O-CD2 3.31Å; A262-F266 WeakPolarHBondContact O-CD2 3.26Å; A262-F266 PolarHBondContact O-N 3.37Å; A262-L283 HydrophobicContact CB-CD1 4Å; A262-L283 HydrophobicContact CB-CD2 3.78Å
263D92.3Very high87.1Confident18 Ų1840.4 Ų40.410%0.09620%0.197CC..Hα-helixtrans-60-40.5-179.7-170.239.1000111.1L259 L260 D261 C267 Y280 L283 Q284 I287 K306L259-D263 PolarHBondContact O-N 3.04Å; L260-D263 PolarHBondContact O-N 2.65Å; D261-D263 PolarHBondContact O-N 3.1Å; D263-C267 PolarHBondContact O-N 3.07Å; D263-C267 PolarHBondContact O-SG 3.27Å; D263-Y280 VanDerWaalsContact OD1-CE2 3.28Å; D263-Y280 WeakPolarHBondContact OD1-CE2 3.15Å; D263-Y280 PolarHBondContact OD1-OH 3.11Å; D263-L283 HydrophobicContact CB-CD2 4.05Å; D263-Q284 PolarHBondContact OD1-NE2 2.91Å; D263-I287 HydrophobicContact CB-CD1 3.91Å; D263-K306 IonicContact OD1-NZ 2.91Å; D263-K306 IonicContact OD2-NZ 2.98Å; D263-K306 PolarHBondContact OD2-NZ 3.39Å
264K90.3Very high87.1Confident91 Ų9140.7 Ų40.740%0.39620%0.195SC..Hα-helixtrans-60.6-48175.3-176-167166-154.90111.7L260 D261 A262 C267 E268L260-K264 PolarHBondContact O-N 3.25Å; L260-K264 VanDerWaalsContact O-N 3.1Å; D261-K264 WeakPolarHBondContact O-CB 3.48Å; D261-K264 PolarHBondContact O-N 3.05Å; A262-K264 VanDerWaalsContact C-N 3.28Å; A262-K264 PolarHBondContact O-N 3.05Å; K264-C267 WeakPolarHBondContact O-CB 3.39Å; K264-C267 PolarHBondContact O-N 3.03Å; K264-E268 PolarHBondContact O-N 3.32Å
265Y90.3Very high86.8Confident28 Ų2843.6 Ų43.611%0.1121%0.211CC..Hα-helixtrans-71.3-34.5-179-72.3-65.6000112.9L235 Y239 D261 A262 C267 E268L235-Y265 HydrophobicContact CB-CD1 4.18Å; L235-Y265 HydrophobicContact CB-CD2 4.02Å; L235-Y265 HydrophobicContact CB-CE1 4.43Å; L235-Y265 HydrophobicContact CB-CE2 4.32Å; L235-Y265 HydrophobicContact CB-CG 3.97Å; L235-Y265 HydrophobicContact CD1-CD1 4.04Å; L235-Y265 HydrophobicContact CD1-CE1 3.64Å; Y239-Y265 AromaticContact CD2-CD2 3.83Å; Y239-Y265 HydrophobicContact CD2-CD2 3.83Å; Y239-Y265 AromaticContact CD2-CE2 3.83Å; Y239-Y265 HydrophobicContact CD2-CE2 3.83Å; Y239-Y265 AromaticContact CE2-CD2 3.97Å; Y239-Y265 HydrophobicContact CE2-CD2 3.97Å; Y239-Y265 AromaticContact CE2-CE2 3.47Å; Y239-Y265 HydrophobicContact CE2-CE2 3.47Å; Y239-Y265 VanDerWaalsContact CE2-CE2 3.47Å; D261-Y265 WeakPolarHBondContact O-CD2 3.49Å; D261-Y265 PolarHBondContact O-N 3.18Å; D261-Y265 VanDerWaalsContact O-N 3.14Å; A262-Y265 PolarHBondContact O-N 3.41Å; A262-Y265 VanDerWaalsContact O-N 3.15Å; Y265-C267 VanDerWaalsContact C-N 3.28Å; Y265-C267 PolarHBondContact O-N 3.21Å; Y265-E268 WeakPolarHBondContact O-CB 3.28Å; Y265-E268 PolarHBondContact O-N 3.12Å; Y265-E268 VanDerWaalsContact O-N 3.12Å
266F91Very high85.9Confident1 Ų147.5 Ų47.50%0.00424%0.235CC..Hα-helixtrans-60.6-40.2170.1-85-64.8000111.3L233 A236 M237 A262 E268 C269 L274 N279 Y280 L283L233-F266 HydrophobicContact CD1-CD1 4.31Å; L233-F266 HydrophobicContact CD1-CE1 3.81Å; A236-F266 HydrophobicContact CB-CB 4.41Å; A236-F266 HydrophobicContact CB-CD1 3.92Å; A236-F266 HydrophobicContact CB-CD2 3.56Å; A236-F266 HydrophobicContact CB-CE1 4.02Å; A236-F266 HydrophobicContact CB-CE2 3.67Å; A236-F266 HydrophobicContact CB-CG 3.69Å; A236-F266 HydrophobicContact CB-CZ 3.9Å; M237-F266 HydrophobicContact CG-CZ 4.34Å; A262-F266 VanDerWaalsContact O-CD2 3.31Å; A262-F266 WeakPolarHBondContact O-CD2 3.26Å; A262-F266 PolarHBondContact O-N 3.37Å; F266-E268 PolarHBondContact O-N 3.24Å; F266-C269 VanDerWaalsContact O-CB 3.31Å; F266-C269 WeakPolarHBondContact O-CB 3.27Å; F266-C269 PolarHBondContact O-N 2.72Å; F266-L274 HydrophobicContact CB-CD2 4.17Å; F266-L274 HydrophobicContact CD1-CD2 3.71Å; F266-L274 HydrophobicContact CG-CD2 4.37Å; F266-L274 WeakPolarHBondContact O-CD1 3.27Å; F266-N279 HydrophobicContact CE1-CB 4.49Å; F266-N279 HydrophobicContact CZ-CB 4.17Å; F266-Y280 HydrophobicContact CB-CD2 3.43Å; F266-Y280 VanDerWaalsContact CB-CD2 3.43Å; F266-Y280 HydrophobicContact CB-CE2 3.61Å; F266-Y280 HydrophobicContact CB-CG 4.42Å; F266-Y280 HydrophobicContact CD1-CD2 4.21Å; F266-Y280 AromaticContact CD2-CD2 3.93Å; F266-Y280 HydrophobicContact CD2-CD2 3.93Å; F266-Y280 AromaticContact CG-CD2 3.61Å; F266-Y280 HydrophobicContact CG-CD2 3.61Å; F266-Y280 HydrophobicContact CG-CE2 4.26Å; F266-Y280 HydrophobicContact CG-CG 4.46Å; F266-L283 HydrophobicContact CD2-CD2 3.37Å; F266-L283 HydrophobicContact CE2-CD2 3.72Å
267C88.4Confident85.5Confident78 Ų7849.3 Ų49.353%0.52725%0.246SC..THydrogen-bonded Turntrans-65.6-15.4176.6-68.60000114.3D263 K264 Y265D263-C267 PolarHBondContact O-N 3.07Å; D263-C267 PolarHBondContact O-SG 3.27Å; K264-C267 WeakPolarHBondContact O-CB 3.39Å; K264-C267 PolarHBondContact O-N 3.03Å; Y265-C267 VanDerWaalsContact C-N 3.28Å; Y265-C267 PolarHBondContact O-N 3.21Å
268E88.4Confident85.5Confident109 Ų10950.4 Ų50.451%0.50925%0.252SS..THydrogen-bonded Turntrans-81.4-16.6172.6-65.9176.4-170.700112.2A232 K264 Y265 F266A232-E268 HydrophobicContact CB-CB 4.12Å; K264-E268 PolarHBondContact O-N 3.32Å; Y265-E268 WeakPolarHBondContact O-CB 3.28Å; Y265-E268 PolarHBondContact O-N 3.12Å; Y265-E268 VanDerWaalsContact O-N 3.12Å; F266-E268 PolarHBondContact O-N 3.24Å
269C85.7Confident85.5Confident9 Ų952.3 Ų52.36%0.06126%0.262CS..SBendtrans-79158.5176.6-57.20000111.6F266 L273 L274F266-C269 VanDerWaalsContact O-CB 3.31Å; F266-C269 WeakPolarHBondContact O-CB 3.27Å; F266-C269 PolarHBondContact O-N 2.72Å; C269-L273 HydrophobicContact CB-CD2 4.32Å; C269-L274 HydrophobicContact CB-CD2 4.26Å; C269-L274 HydrophobicContact CB-CG 4.41Å
270C81.9Confident85.4Confident43 Ų4353.3 Ų53.329%0.29127%0.266SS..  trans-68.6150.3179.572.30000111.8E229 E272 L273 L274E229-C270 VanDerWaalsContact CD-SG 3.57Å; E229-C270 VanDerWaalsContact OE1-CB 3.31Å; E229-C270 WeakPolarHBondContact OE1-CB 3.35Å; E229-C270 PolarHBondContact OE1-SG 2.95Å; E229-C270 PolarHBondContact OE2-N 3.44Å; E229-C270 PolarHBondContact OE2-SG 3.27Å; C270-E272 VanDerWaalsContact C-N 3.27Å; C270-E272 PolarHBondContact O-N 3.09Å; C270-L273 PolarHBondContact O-N 3.32Å; C270-L273 VanDerWaalsContact SG-CB 3.6Å; C270-L274 PolarHBondContact O-N 3.33Å
271R79.9Confident85.5Confident208 Ų20852.9 Ų52.979%0.78526%0.264SS*.Hα-helixtrans-63.2-34-177.8-70.5-176.2177.5170.40.4113L273 L274 D275R271-L273 VanDerWaalsContact C-N 3.31Å; R271-L273 PolarHBondContact O-N 2.92Å; R271-L274 PolarHBondContact O-N 3.43Å; R271-D275 WeakPolarHBondContact O-CB 3.43Å; R271-D275 PolarHBondContact O-N 2.98Å
272E78.6Confident85.7Confident160 Ų16051.2 Ų51.275%0.74826%0.255SS*.Hα-helixtrans-61.2-41.3179.3-67.2161.1-166.200111.4C270 T276C270-E272 VanDerWaalsContact C-N 3.27Å; C270-E272 PolarHBondContact O-N 3.09Å; E272-T276 WeakPolarHBondContact O-CG2 3.28Å; E272-T276 PolarHBondContact O-OG1 3.38Å
273L78.6Confident85.8Confident34 Ų3451.2 Ų51.218%0.17826%0.255CS..Hα-helixtrans-65.5-48.5174.2-17965.2000111L233 C269 C270 R271 D275 T276 V277L233-L273 HydrophobicContact CD1-CD2 4.37Å; L233-L273 HydrophobicContact CD2-CD2 4.06Å; C269-L273 HydrophobicContact CB-CD2 4.32Å; C270-L273 PolarHBondContact O-N 3.32Å; C270-L273 VanDerWaalsContact SG-CB 3.6Å; R271-L273 VanDerWaalsContact C-N 3.31Å; R271-L273 PolarHBondContact O-N 2.92Å; L273-D275 VanDerWaalsContact C-N 3.29Å; L273-D275 PolarHBondContact O-N 2.74Å; L273-T276 PolarHBondContact O-N 2.89Å; L273-T276 VanDerWaalsContact O-N 3.14Å; L273-T276 PolarHBondContact O-OG1 2.75Å; L273-V277 HydrophobicContact CD1-CG1 4.4Å; L273-V277 WeakPolarHBondContact O-CG2 3.43Å; L273-V277 PolarHBondContact O-N 3.23Å
274L80.3Confident85.8Confident17 Ų1750.4 Ų50.49%0.08925%0.251CS..Hα-helixtrans-64.7-30.3-177.7-62.5177.2000113.7F266 C269 C270 R271 T276 Y280F266-L274 HydrophobicContact CB-CD2 4.17Å; F266-L274 HydrophobicContact CD1-CD2 3.71Å; F266-L274 HydrophobicContact CG-CD2 4.37Å; F266-L274 WeakPolarHBondContact O-CD1 3.27Å; C269-L274 HydrophobicContact CB-CD2 4.26Å; C269-L274 HydrophobicContact CB-CG 4.41Å; C270-L274 PolarHBondContact O-N 3.33Å; R271-L274 PolarHBondContact O-N 3.43Å; L274-T276 VanDerWaalsContact C-N 3.27Å; L274-T276 PolarHBondContact O-N 3.15Å; L274-Y280 HydrophobicContact CB-CD1 4.43Å; L274-Y280 HydrophobicContact CD2-CD1 4.46Å; L274-Y280 HydrophobicContact CD2-CD2 4.49Å; L274-Y280 HydrophobicContact CD2-CG 4.13Å
275D75.2Confident86Confident67 Ų6746.2 Ų46.236%0.35823%0.232SC..Hα-helixtrans-76.9-13.6178.5-80.1-25.1000113R271 L273R271-D275 WeakPolarHBondContact O-CB 3.43Å; R271-D275 PolarHBondContact O-N 2.98Å; L273-D275 VanDerWaalsContact C-N 3.29Å; L273-D275 PolarHBondContact O-N 2.74Å
276T72.7Confident86.2Confident82 Ų8245.6 Ų45.650%0.50323%0.231SC..Hα-helixtrans-104.5-12.7-177.257.80000114.5E272 L273 L274E272-T276 WeakPolarHBondContact O-CG2 3.28Å; E272-T276 PolarHBondContact O-OG1 3.38Å; L273-T276 PolarHBondContact O-N 2.89Å; L273-T276 VanDerWaalsContact O-N 3.14Å; L273-T276 PolarHBondContact O-OG1 2.75Å; L274-T276 VanDerWaalsContact C-N 3.27Å; L274-T276 PolarHBondContact O-N 3.15Å
277V79.1Confident86.3Confident39 Ų3945.5 Ų45.524%0.23623%0.231CC..  trans-115.5145.6-179.4-570000111.5L273L273-V277 HydrophobicContact CD1-CG1 4.4Å; L273-V277 WeakPolarHBondContact O-CG2 3.43Å; L273-V277 PolarHBondContact O-N 3.23Å
278D86.3Confident86.5Confident23 Ų2342 Ų4212%0.12321%0.206CC..SBendtrans-88.6-17.5179.557.80.4000113.2Y280 A281 V282 F314 C317 Y318D278-Y280 PolarHBondContact O-N 2.94Å; D278-Y280 VanDerWaalsContact O-N 3.15Å; D278-A281 WeakPolarHBondContact O-CA 3.49Å; D278-A281 VanDerWaalsContact O-CB 3.28Å; D278-A281 WeakPolarHBondContact O-CB 3.3Å; D278-A281 PolarHBondContact O-N 3.41Å; D278-V282 WeakPolarHBondContact O-CG2 3.41Å; D278-V282 PolarHBondContact O-N 3.17Å; D278-F314 HydrophobicContact CB-CD1 4.38Å; D278-F314 HydrophobicContact CB-CE1 4.35Å; D278-C317 HydrophobicContact CB-CB 4.31Å; D278-Y318 HydrophobicContact CB-CE1 4.2Å; D278-Y318 VanDerWaalsContact CB-OH 3.27Å; D278-Y318 WeakPolarHBondContact CB-OH 3.42Å; D278-Y318 VanDerWaalsContact CG-OH 3.29Å; D278-Y318 WeakPolarHBondContact OD2-CE1 3.31Å; D278-Y318 VanDerWaalsContact OD2-CZ 3.31Å; D278-Y318 PolarHBondContact OD2-OH 2.85Å
279N89.8Confident86.7Confident42 Ų4237 Ų3723%0.22518%0.183CC..Hα-helixtrans-49.7-43.9178.7-64.581.5000112.8F266 A281 V282 L283F266-N279 HydrophobicContact CE1-CB 4.49Å; F266-N279 HydrophobicContact CZ-CB 4.17Å; N279-A281 VanDerWaalsContact C-N 3.34Å; N279-A281 PolarHBondContact O-N 3.43Å; N279-V282 PolarHBondContact O-N 3.23Å; N279-L283 PolarHBondContact O-N 3.24Å
280Y91.3Very high86.9Confident22 Ų2236.6 Ų36.69%0.08618%0.18CC..Hα-helixtrans-65.9-37.4179.2-174.9-125.1000112.3D263 F266 L274 D278 L283 Q284 L309D263-Y280 VanDerWaalsContact OD1-CE2 3.28Å; D263-Y280 WeakPolarHBondContact OD1-CE2 3.15Å; D263-Y280 PolarHBondContact OD1-OH 3.11Å; F266-Y280 HydrophobicContact CB-CD2 3.43Å; F266-Y280 VanDerWaalsContact CB-CD2 3.43Å; F266-Y280 HydrophobicContact CB-CE2 3.61Å; F266-Y280 HydrophobicContact CB-CG 4.42Å; F266-Y280 HydrophobicContact CD1-CD2 4.21Å; F266-Y280 AromaticContact CD2-CD2 3.93Å; F266-Y280 HydrophobicContact CD2-CD2 3.93Å; F266-Y280 AromaticContact CG-CD2 3.61Å; F266-Y280 HydrophobicContact CG-CD2 3.61Å; F266-Y280 HydrophobicContact CG-CE2 4.26Å; F266-Y280 HydrophobicContact CG-CG 4.46Å; L274-Y280 HydrophobicContact CB-CD1 4.43Å; L274-Y280 HydrophobicContact CD2-CD1 4.46Å; L274-Y280 HydrophobicContact CD2-CD2 4.49Å; L274-Y280 HydrophobicContact CD2-CG 4.13Å; D278-Y280 PolarHBondContact O-N 2.94Å; D278-Y280 VanDerWaalsContact O-N 3.15Å; Y280-L283 HydrophobicContact CD2-CD2 4.46Å; Y280-L283 PolarHBondContact O-N 2.55Å; Y280-Q284 VanDerWaalsContact CZ-NE2 3.29Å; Y280-Q284 WeakPolarHBondContact O-CG 3.27Å; Y280-Q284 PolarHBondContact O-N 3.15Å; Y280-Q284 VanDerWaalsContact O-N 3.11Å; Y280-Q284 PolarHBondContact OH-NE2 2.94Å; Y280-L309 HydrophobicContact CD1-CD2 3.64Å; Y280-L309 HydrophobicContact CE1-CD1 3.92Å; Y280-L309 HydrophobicContact CE1-CD2 3.37Å; Y280-L309 HydrophobicContact CE1-CG 4.29Å
281A91.9Very high87.2Confident0 Ų034.6 Ų34.60%017%0.167CC..Hα-helixtrans-67.5-42176.100000111.9D278 N279 L283 Q284 L285 A310 C313 F314D278-A281 WeakPolarHBondContact O-CA 3.49Å; D278-A281 VanDerWaalsContact O-CB 3.28Å; D278-A281 WeakPolarHBondContact O-CB 3.3Å; D278-A281 PolarHBondContact O-N 3.41Å; N279-A281 VanDerWaalsContact C-N 3.34Å; N279-A281 PolarHBondContact O-N 3.43Å; A281-L283 VanDerWaalsContact C-N 3.33Å; A281-Q284 WeakPolarHBondContact O-CB 3.35Å; A281-Q284 PolarHBondContact O-N 3.05Å; A281-L285 PolarHBondContact O-N 2.95Å; A281-L285 VanDerWaalsContact O-N 3.09Å; A281-A310 HydrophobicContact CB-CB 4.32Å; A281-C313 HydrophobicContact CB-CB 3.53Å; A281-F314 HydrophobicContact CB-CD1 3.76Å; A281-F314 HydrophobicContact CB-CE1 3.39Å; A281-F314 HydrophobicContact CB-CE2 4.29Å; A281-F314 HydrophobicContact CB-CG 4.37Å; A281-F314 HydrophobicContact CB-CZ 3.68Å
282V94.1Very high87.6Confident4 Ų426 Ų262%0.02414%0.135CC..Hα-helixtrans-61.8-43.2175178.20000110.4D278 N279 Q284 L285 D286 F314 L338 Y572D278-V282 WeakPolarHBondContact O-CG2 3.41Å; D278-V282 PolarHBondContact O-N 3.17Å; N279-V282 PolarHBondContact O-N 3.23Å; V282-Q284 VanDerWaalsContact C-N 3.32Å; V282-Q284 PolarHBondContact O-N 3.4Å; V282-L285 WeakPolarHBondContact O-CB 3.36Å; V282-L285 PolarHBondContact O-N 3.33Å; V282-L285 VanDerWaalsContact O-N 3.12Å; V282-D286 PolarHBondContact O-N 3.36Å; V282-F314 HydrophobicContact CG2-CE1 4Å; V282-F314 HydrophobicContact CG2-CZ 4.22Å; V282-L338 HydrophobicContact CG2-CD1 3.94Å; V282-L338 HydrophobicContact CG2-CD2 4.13Å; V282-Y572 HydrophobicContact CG1-CD2 4.09Å; V282-Y572 HydrophobicContact CG2-CD2 4.31Å; V282-Y572 HydrophobicContact CG2-CE2 4.02Å
283L94.8Very high88.1Confident0 Ų021.5 Ų21.50%011%0.111CC..Hα-helixtrans-57.7-44174.3174.765.2000112.1H240 L259 A262 D263 F266 N279 Y280 A281 L285 D286 I287H240-L283 HydrophobicContact CB-CD1 4.43Å; H240-L283 PolarHBondContact CE1-N 3.23Å; L259-L283 HydrophobicContact CB-CD1 3.93Å; L259-L283 HydrophobicContact CD2-CD1 3.67Å; L259-L283 HydrophobicContact CG-CD1 4.39Å; A262-L283 HydrophobicContact CB-CD1 4Å; A262-L283 HydrophobicContact CB-CD2 3.78Å; D263-L283 HydrophobicContact CB-CD2 4.05Å; F266-L283 HydrophobicContact CD2-CD2 3.37Å; F266-L283 HydrophobicContact CE2-CD2 3.72Å; N279-L283 PolarHBondContact O-N 3.24Å; Y280-L283 HydrophobicContact CD2-CD2 4.46Å; Y280-L283 PolarHBondContact O-N 2.55Å; A281-L283 VanDerWaalsContact C-N 3.33Å; L283-L285 VanDerWaalsContact C-N 3.29Å; L283-L285 PolarHBondContact O-N 3.4Å; L283-D286 PolarHBondContact O-N 3.09Å; L283-I287 HydrophobicContact CD1-CD1 3.99Å; L283-I287 HydrophobicContact CD1-CG1 4.13Å; L283-I287 HydrophobicContact CD2-CD1 4.45Å; L283-I287 HydrophobicContact CG-CD1 3.85Å; L283-I287 HydrophobicContact CG-CG1 4.42Å; L283-I287 VanDerWaalsContact O-CG1 3.3Å; L283-I287 WeakPolarHBondContact O-CG1 3.28Å; L283-I287 PolarHBondContact O-N 2.96Å
284Q93.5Very high88.3Confident2 Ų221.3 Ų21.31%0.00911%0.11CC..Hα-helixtrans-60.9-39.7177.1-64.3-38.3-60.600111.9D263 Y280 A281 V282 V288 K306 L309 A310D263-Q284 PolarHBondContact OD1-NE2 2.91Å; Y280-Q284 VanDerWaalsContact CZ-NE2 3.29Å; Y280-Q284 WeakPolarHBondContact O-CG 3.27Å; Y280-Q284 PolarHBondContact O-N 3.15Å; Y280-Q284 VanDerWaalsContact O-N 3.11Å; Y280-Q284 PolarHBondContact OH-NE2 2.94Å; A281-Q284 WeakPolarHBondContact O-CB 3.35Å; A281-Q284 PolarHBondContact O-N 3.05Å; V282-Q284 VanDerWaalsContact C-N 3.32Å; V282-Q284 PolarHBondContact O-N 3.4Å; Q284-V288 WeakPolarHBondContact O-CG2 3.02Å; Q284-V288 PolarHBondContact O-N 2.92Å; Q284-K306 HydrophobicContact CB-CB 4.15Å; Q284-L309 HydrophobicContact CG-CD2 3.76Å; Q284-A310 HydrophobicContact CB-CB 4.18Å
285L93.8Very high88.2Confident2 Ų224.5 Ų24.51%0.0112%0.124CC..Hα-helixtrans-62.3-47174-71.9-172.7000111.8A281 V282 L283 I287 V288 W289 L307 A310 F314 L338 L342 L345A281-L285 PolarHBondContact O-N 2.95Å; A281-L285 VanDerWaalsContact O-N 3.09Å; V282-L285 WeakPolarHBondContact O-CB 3.36Å; V282-L285 PolarHBondContact O-N 3.33Å; V282-L285 VanDerWaalsContact O-N 3.12Å; L283-L285 VanDerWaalsContact C-N 3.29Å; L283-L285 PolarHBondContact O-N 3.4Å; L285-I287 VanDerWaalsContact C-N 3.32Å; L285-I287 PolarHBondContact O-N 3.44Å; L285-V288 PolarHBondContact O-N 3.12Å; L285-W289 WeakPolarHBondContact O-CB 3.18Å; L285-W289 PolarHBondContact O-N 3.37Å; L285-L307 HydrophobicContact CD2-CD2 3.91Å; L285-A310 HydrophobicContact CD2-CB 4.07Å; L285-A310 HydrophobicContact CG-CB 4.18Å; L285-F314 HydrophobicContact CD1-CE2 3.55Å; L285-F314 HydrophobicContact CD1-CZ 3.6Å; L285-F314 HydrophobicContact CD2-CE2 4.49Å; L285-F314 HydrophobicContact CG-CE2 3.98Å; L285-F314 HydrophobicContact CG-CZ 4.11Å; L285-L338 HydrophobicContact CD1-CB 4.44Å; L285-L342 HydrophobicContact CD1-CB 4.43Å; L285-L342 HydrophobicContact CD2-CB 3.95Å; L285-L342 HydrophobicContact CD2-CD1 3.7Å; L285-L342 HydrophobicContact CD2-CG 4.44Å; L285-L345 HydrophobicContact CD2-CD1 4.48Å
286D94.6Very high88.1Confident15 Ų1521.5 Ų21.58%0.0811%0.108CC..Hα-helixtrans-61.8-39.5-178.6-73.8-22.2000111.9H240 L247 L259 V282 L283 W289 C290H240-D286 IonicContact CD2-OD2 3.59Å; H240-D286 IonicContact CE1-OD2 3.76Å; H240-D286 IonicContact NE2-OD2 3.1Å; H240-D286 PolarHBondContact NE2-OD2 3.22Å; L247-D286 HydrophobicContact CD1-CB 3.86Å; L259-D286 HydrophobicContact CD1-CB 4.17Å; L259-D286 HydrophobicContact CD2-CB 4.29Å; V282-D286 PolarHBondContact O-N 3.36Å; L283-D286 PolarHBondContact O-N 3.09Å; D286-W289 WeakPolarHBondContact O-CB 3.2Å; D286-W289 PolarHBondContact O-N 3.11Å; D286-C290 PolarHBondContact O-N 3.16Å
287I93.1Very high87.8Confident0 Ų019 Ų190%09%0.092CC..Hα-helixtrans-63.2-45.4174.7-69.4166.3000111L256 L259 L260 D263 L283 L285 W289 C290 Y291 K306L256-I287 HydrophobicContact CD1-CG2 4.17Å; L259-I287 HydrophobicContact CB-CD1 4.41Å; L259-I287 HydrophobicContact CB-CG1 3.64Å; L259-I287 HydrophobicContact CD1-CG1 4.41Å; L260-I287 HydrophobicContact CD2-CD1 4.46Å; L260-I287 HydrophobicContact CD2-CG2 4.34Å; D263-I287 HydrophobicContact CB-CD1 3.91Å; L283-I287 HydrophobicContact CD1-CD1 3.99Å; L283-I287 HydrophobicContact CD1-CG1 4.13Å; L283-I287 HydrophobicContact CD2-CD1 4.45Å; L283-I287 HydrophobicContact CG-CD1 3.85Å; L283-I287 HydrophobicContact CG-CG1 4.42Å; L283-I287 VanDerWaalsContact O-CG1 3.3Å; L283-I287 WeakPolarHBondContact O-CG1 3.28Å; L283-I287 PolarHBondContact O-N 2.96Å; L285-I287 VanDerWaalsContact C-N 3.32Å; L285-I287 PolarHBondContact O-N 3.44Å; I287-W289 VanDerWaalsContact C-N 3.33Å; I287-C290 VanDerWaalsContact O-CB 3.28Å; I287-C290 WeakPolarHBondContact O-CB 3.33Å; I287-C290 PolarHBondContact O-N 2.76Å; I287-Y291 HydrophobicContact CG2-CD2 4.1Å; I287-Y291 HydrophobicContact CG2-CE1 4.19Å; I287-Y291 HydrophobicContact CG2-CE2 3.21Å; I287-Y291 VanDerWaalsContact CG2-OH 3.27Å; I287-Y291 WeakPolarHBondContact CG2-OH 3.43Å; I287-Y291 WeakPolarHBondContact O-CD2 3.18Å; I287-Y291 PolarHBondContact O-N 3.49Å; I287-K306 HydrophobicContact CB-CD 4.3Å; I287-K306 HydrophobicContact CG2-CD 3.83Å
288V92.8Very high86.8Confident3 Ų320.5 Ų20.52%0.01810%0.096CC..Hα-helixtrans-68-35.9179.2178.20000111.4Q284 L285 C290 Y291 F292 A303 K306 L307 L345Q284-V288 WeakPolarHBondContact O-CG2 3.02Å; Q284-V288 PolarHBondContact O-N 2.92Å; L285-V288 PolarHBondContact O-N 3.12Å; V288-C290 VanDerWaalsContact C-N 3.35Å; V288-Y291 PolarHBondContact O-N 3.4Å; V288-F292 PolarHBondContact O-N 3.19Å; V288-A303 HydrophobicContact CG1-CB 4.35Å; V288-A303 HydrophobicContact CG2-CB 4.34Å; V288-K306 HydrophobicContact CG2-CB 3.78Å; V288-K306 HydrophobicContact CG2-CD 4.25Å; V288-L307 HydrophobicContact CB-CD2 4.35Å; V288-L307 HydrophobicContact CG1-CD1 4.22Å; V288-L307 HydrophobicContact CG1-CD2 4.08Å; V288-L307 HydrophobicContact CG1-CG 4.15Å; V288-L307 HydrophobicContact CG2-CD2 4.39Å; V288-L307 HydrophobicContact CG2-CG 4.26Å; V288-L345 HydrophobicContact CB-CD1 4.18Å; V288-L345 HydrophobicContact CG1-CB 4.36Å; V288-L345 HydrophobicContact CG1-CD1 4.01Å; V288-L345 HydrophobicContact CG1-CD2 4.23Å; V288-L345 HydrophobicContact CG1-CG 4.44Å
289W92.8Very high85.4Confident6 Ų620.1 Ų20.12%0.02310%0.095CC..Hα-helixtrans-59.6-45.1171.2-174.1-102.2000111.5L285 D286 I287 Y291 F292 R293 R341 L344 L345 D579 E580 I583L285-W289 WeakPolarHBondContact O-CB 3.18Å; L285-W289 PolarHBondContact O-N 3.37Å; D286-W289 WeakPolarHBondContact O-CB 3.2Å; D286-W289 PolarHBondContact O-N 3.11Å; I287-W289 VanDerWaalsContact C-N 3.33Å; W289-Y291 PolarHBondContact O-N 2.87Å; W289-F292 WeakPolarHBondContact O-CB 3.41Å; W289-F292 PolarHBondContact O-N 3.39Å; W289-R293 HydrophobicContact CD2-CG 4.49Å; W289-R293 HydrophobicContact CG-CG 4.49Å; W289-R293 WeakPolarHBondContact O-CG 3.47Å; W289-R293 PolarHBondContact O-N 3.48Å; W289-R341 HydrophobicContact CE3-CG 4.17Å; W289-R341 HydrophobicContact CZ3-CG 4.41Å; W289-L344 HydrophobicContact CZ3-CD2 4.26Å; W289-L345 HydrophobicContact CB-CD1 4.45Å; W289-L345 HydrophobicContact CE3-CD1 4.38Å; W289-L345 HydrophobicContact CE3-CD2 3.94Å; W289-L345 HydrophobicContact CE3-CG 4.32Å; W289-D579 HydrophobicContact CH2-CB 4.46Å; W289-D579 HydrophobicContact CZ2-CB 4.29Å; W289-E580 HydrophobicContact CH2-CG 4.38Å; W289-I583 HydrophobicContact CH2-CD1 3.52Å; W289-I583 HydrophobicContact CZ2-CD1 4.3Å; W289-I583 HydrophobicContact CZ3-CD1 4.15Å
290C91.1Very high83.7Confident0 Ų019.1 Ų19.10%09%0.09CC..Hα-helixtrans-55.7-47172.3-98.70000112.5L247 L256 D286 I287 V288 F292 R293 L294L247-C290 WeakPolarHBondContact CD2-SG 3.42Å; L256-C290 HydrophobicContact CB-CB 4.13Å; L256-C290 HydrophobicContact CD1-CB 4.05Å; D286-C290 PolarHBondContact O-N 3.16Å; I287-C290 VanDerWaalsContact O-CB 3.28Å; I287-C290 WeakPolarHBondContact O-CB 3.33Å; I287-C290 PolarHBondContact O-N 2.76Å; V288-C290 VanDerWaalsContact C-N 3.35Å; C290-F292 VanDerWaalsContact C-N 3.3Å; C290-F292 PolarHBondContact O-N 2.79Å; C290-R293 PolarHBondContact O-N 2.79Å; C290-L294 WeakPolarHBondContact O-CB 3.42Å; C290-L294 VanDerWaalsContact O-CG 3.26Å; C290-L294 WeakPolarHBondContact O-CG 3.35Å; C290-L294 PolarHBondContact O-N 3.25Å
291Y87.7Confident82.2Confident1 Ų124.1 Ų24.10%0.00412%0.118CC..Hα-helixtrans-61.6-39.8177.9-59.9-38.2000112.9M154 L256 I287 V288 W289 E295 Q296 L300 K306M154-Y291 HydrophobicContact CE-CD1 4.45Å; M154-Y291 HydrophobicContact SD-CD1 4.29Å; M154-Y291 HydrophobicContact SD-CE1 4.44Å; L256-Y291 HydrophobicContact CD1-CD1 4.1Å; L256-Y291 HydrophobicContact CD1-CE1 3.41Å; L256-Y291 VanDerWaalsContact CD1-CE1 3.41Å; L256-Y291 HydrophobicContact CD2-CD1 3.93Å; L256-Y291 HydrophobicContact CD2-CE1 3.62Å; L256-Y291 HydrophobicContact CG-CE1 4.15Å; I287-Y291 HydrophobicContact CG2-CD2 4.1Å; I287-Y291 HydrophobicContact CG2-CE1 4.19Å; I287-Y291 HydrophobicContact CG2-CE2 3.21Å; I287-Y291 VanDerWaalsContact CG2-OH 3.27Å; I287-Y291 WeakPolarHBondContact CG2-OH 3.43Å; I287-Y291 WeakPolarHBondContact O-CD2 3.18Å; I287-Y291 PolarHBondContact O-N 3.49Å; V288-Y291 PolarHBondContact O-N 3.4Å; W289-Y291 PolarHBondContact O-N 2.87Å; Y291-E295 PolarHBondContact O-N 2.88Å; Y291-Q296 PolarHBondContact O-N 3.48Å; Y291-L300 HydrophobicContact CD1-CD1 3.72Å; Y291-L300 HydrophobicContact CD2-CD1 3.43Å; Y291-L300 VanDerWaalsContact CD2-CD1 3.43Å; Y291-L300 HydrophobicContact CE1-CD1 3.26Å; Y291-L300 HydrophobicContact CE2-CD1 2.94Å; Y291-L300 HydrophobicContact CE2-CG 4.31Å; Y291-L300 HydrophobicContact CG-CD1 3.81Å; Y291-L300 WeakPolarHBondContact OH-CD1 3.38Å; Y291-K306 HydrophobicContact CE2-CD 4.5Å
292F88Confident81.3Confident26 Ų2624.5 Ų24.511%0.11412%0.12CC..Hα-helixtrans-60.7-51.3174.8173.2-107.2000111.1V288 W289 C290 L294 E295 L297 L345 I348 I583 Y587V288-F292 PolarHBondContact O-N 3.19Å; W289-F292 WeakPolarHBondContact O-CB 3.41Å; W289-F292 PolarHBondContact O-N 3.39Å; C290-F292 VanDerWaalsContact C-N 3.3Å; C290-F292 PolarHBondContact O-N 2.79Å; F292-L294 VanDerWaalsContact C-N 3.27Å; F292-L294 PolarHBondContact O-N 3.46Å; F292-E295 WeakPolarHBondContact O-CA 3.24Å; F292-E295 PolarHBondContact O-N 3.18Å; F292-L297 HydrophobicContact CB-CD2 4.01Å; F292-L297 HydrophobicContact CD2-CD1 4.09Å; F292-L297 HydrophobicContact CD2-CD2 4.28Å; F292-L297 HydrophobicContact CD2-CG 4.46Å; F292-L345 HydrophobicContact CB-CD2 4.17Å; F292-L345 HydrophobicContact CG-CD2 4.45Å; F292-I348 HydrophobicContact CD2-CD1 4.18Å; F292-I348 HydrophobicContact CD2-CG2 3.86Å; F292-I348 HydrophobicContact CE2-CD1 3.86Å; F292-I348 HydrophobicContact CE2-CG2 3.88Å; F292-I348 HydrophobicContact CZ-CD1 4.06Å; F292-I583 HydrophobicContact CE1-CD1 3.66Å; F292-I583 HydrophobicContact CE1-CG1 4.21Å; F292-I583 HydrophobicContact CE1-CG2 4.25Å; F292-I583 HydrophobicContact CZ-CD1 4.27Å; F292-I583 HydrophobicContact CZ-CG1 4.35Å; F292-I583 HydrophobicContact CZ-CG2 3.85Å; F292-Y587 HydrophobicContact CE2-CE2 4.04Å; F292-Y587 HydrophobicContact CZ-CE2 4.16Å
293R87.9Confident80.8Confident67 Ų6724.5 Ų24.525%0.25312%0.121SC..Hα-helixtrans-67.6-24.6-177.7-63.9-61.9-71.5-103.57.7114Y252 W289 C290 E295 D579Y252-R293 HydrophobicContact CD1-CB 3.78Å; Y252-R293 HydrophobicContact CD1-CG 4.08Å; Y252-R293 HydrophobicContact CD2-CB 3.71Å; Y252-R293 HydrophobicContact CD2-CG 4.45Å; Y252-R293 HydrophobicContact CE1-CB 3.88Å; Y252-R293 HydrophobicContact CE1-CG 3.7Å; Y252-R293 HydrophobicContact CE2-CB 3.81Å; Y252-R293 HydrophobicContact CE2-CG 4.1Å; Y252-R293 HydrophobicContact CG-CB 3.71Å; Y252-R293 HydrophobicContact CG-CG 4.46Å; Y252-R293 PolarHBondContact OH-NE 2.86Å; Y252-R293 PolarHBondContact OH-NH1 2.78Å; Y252-R293 PolarHBondContact OH-NH2 2.86Å; Y252-R293 VanDerWaalsContact OH-NH2 3.07Å; W289-R293 HydrophobicContact CD2-CG 4.49Å; W289-R293 HydrophobicContact CG-CG 4.49Å; W289-R293 WeakPolarHBondContact O-CG 3.47Å; W289-R293 PolarHBondContact O-N 3.48Å; C290-R293 PolarHBondContact O-N 2.79Å; R293-E295 VanDerWaalsContact C-N 3.28Å; R293-D579 IonicContact CZ-OD2 2.94Å; R293-D579 IonicContact NH1-OD2 2.75Å; R293-D579 PolarHBondContact NH1-OD2 3.29Å; R293-D579 IonicContact NH2-OD2 3.99Å
294L83.3Confident80.4Confident30 Ų3028.3 Ų28.316%0.15714%0.138CC..THydrogen-bonded Turntrans-85.61.3172.6-65.9168.5000113M154 L156 L256 C290 F292 Q296M154-L294 HydrophobicContact CE-CB 3.87Å; M154-L294 HydrophobicContact CE-CD1 3.6Å; M154-L294 HydrophobicContact CE-CG 4.37Å; L156-L294 HydrophobicContact CD2-CD1 3.72Å; L256-L294 HydrophobicContact CB-CD1 4.36Å; L256-L294 HydrophobicContact CD2-CD1 3.75Å; C290-L294 WeakPolarHBondContact O-CB 3.42Å; C290-L294 VanDerWaalsContact O-CG 3.26Å; C290-L294 WeakPolarHBondContact O-CG 3.35Å; C290-L294 PolarHBondContact O-N 3.25Å; F292-L294 VanDerWaalsContact C-N 3.27Å; F292-L294 PolarHBondContact O-N 3.46Å; L294-Q296 HydrophobicContact CB-CG 4.46Å; L294-Q296 VanDerWaalsContact O-CG 3.27Å; L294-Q296 WeakPolarHBondContact O-CG 3.48Å; L294-Q296 PolarHBondContact O-N 3.33Å
295E78.6Confident80.1Confident83 Ų8334.5 Ų34.539%0.38817%0.165SC..THydrogen-bonded Turntrans57.524.9-175.8-51.4-173.215600115.2M1 P91 K94 Y291 F292 R293M1-E295 WeakPolarHBondContact CE-OE2 3.46Å; P91-E295 WeakPolarHBondContact CB-OE2 3.45Å; P91-E295 HydrophobicContact CG-CB 4.19Å; P91-E295 HydrophobicContact CG-CG 4.06Å; P91-E295 WeakPolarHBondContact CG-OE2 3.47Å; K94-E295 IonicContact NZ-OE2 2.69Å; K94-E295 PolarHBondContact NZ-OE2 3.14Å; Y291-E295 PolarHBondContact O-N 2.88Å; F292-E295 WeakPolarHBondContact O-CA 3.24Å; F292-E295 PolarHBondContact O-N 3.18Å; R293-E295 VanDerWaalsContact C-N 3.28Å
296Q72.2Confident79.9Confident5 Ų534.8 Ų34.82%0.02317%0.166CC..  trans-114.540.7-175.8-55.1-153.42.900112.7F88 L89 M154 Y291 L294 E298 C299F88-Q296 PolarHBondContact O-NE2 3.19Å; L89-Q296 PolarHBondContact O-NE2 2.78Å; M154-Q296 VanDerWaalsContact CB-OE1 3.32Å; M154-Q296 HydrophobicContact CE-CB 3.67Å; M154-Q296 VanDerWaalsContact CE-CD 3.48Å; M154-Q296 HydrophobicContact CE-CG 3.72Å; M154-Q296 VanDerWaalsContact CE-OE1 3.31Å; M154-Q296 HydrophobicContact SD-CB 4.03Å; M154-Q296 HydrophobicContact SD-CG 4.43Å; M154-Q296 PolarHBondContact SD-OE1 2.83Å; Y291-Q296 PolarHBondContact O-N 3.48Å; L294-Q296 HydrophobicContact CB-CG 4.46Å; L294-Q296 VanDerWaalsContact O-CG 3.27Å; L294-Q296 WeakPolarHBondContact O-CG 3.48Å; L294-Q296 PolarHBondContact O-N 3.33Å; Q296-E298 PolarHBondContact O-N 2.91Å; Q296-E298 VanDerWaalsContact O-N 3.11Å; Q296-C299 HydrophobicContact CB-CB 4.42Å; Q296-C299 WeakPolarHBondContact O-CB 3.17Å; Q296-C299 PolarHBondContact O-N 3.14Å; Q296-C299 VanDerWaalsContact O-N 3.14Å; Q296-C299 PolarHBondContact OE1-SG 2.78Å
297L67.4Low79.8Confident29 Ų2934.2 Ų34.215%0.15216%0.163CC..G310 helixtrans-54.4-29.1174.6-67.1166.8000113.3F292 C299 I348 H352F292-L297 HydrophobicContact CB-CD2 4.01Å; F292-L297 HydrophobicContact CD2-CD1 4.09Å; F292-L297 HydrophobicContact CD2-CD2 4.28Å; F292-L297 HydrophobicContact CD2-CG 4.46Å; L297-C299 VanDerWaalsContact C-N 3.32Å; L297-C299 PolarHBondContact O-N 3.33Å; L297-I348 HydrophobicContact CD1-CG2 3.92Å; L297-H352 WeakPolarHBondContact CD1-CD2 3.16Å; L297-H352 WeakPolarHBondContact CD1-NE2 3.3Å
298E57.2Low79.7Confident71 Ų7138 Ų3833%0.33218%0.183SC..G310 helixtrans-76-17.3-177.2-67.8169.1156.100114.1K5 F88 K152 Q296 L300K5-E298 HydrophobicContact CD-CG 4.27Å; K5-E298 WeakPolarHBondContact CD-OE1 3.31Å; K5-E298 WeakPolarHBondContact CE-OE1 3.39Å; K5-E298 VanDerWaalsContact CE-OE2 3.24Å; K5-E298 WeakPolarHBondContact CE-OE2 3.37Å; K5-E298 VanDerWaalsContact CG-OE1 3.31Å; K5-E298 WeakPolarHBondContact CG-OE1 3.41Å; K5-E298 IonicContact NZ-OE1 3.7Å; K5-E298 PolarHBondContact NZ-OE1 2.77Å; K5-E298 IonicContact NZ-OE2 3.3Å; K5-E298 PolarHBondContact NZ-OE2 3.36Å; F88-E298 HydrophobicContact CE1-CB 3.94Å; F88-E298 HydrophobicContact CZ-CB 4.41Å; K152-E298 PolarHBondContact NZ-O 3.44Å; Q296-E298 PolarHBondContact O-N 2.91Å; Q296-E298 VanDerWaalsContact O-N 3.11Å; E298-L300 PolarHBondContact O-N 3.03Å; E298-L300 VanDerWaalsContact O-N 3.14Å
299C57.7Low79.6Confident14 Ų1440.6 Ų40.610%0.09520%0.197CC..G310 helixtrans-67.6-11-178.8-75.50000112.2F88 M154 Q296 L297F88-C299 WeakPolarHBondContact CB-SG 3.29Å; F88-C299 WeakPolarHBondContact CD2-SG 3.4Å; F88-C299 WeakPolarHBondContact CG-SG 3.46Å; M154-C299 HydrophobicContact CB-CB 4.33Å; M154-C299 HydrophobicContact SD-CB 4.36Å; Q296-C299 HydrophobicContact CB-CB 4.42Å; Q296-C299 WeakPolarHBondContact O-CB 3.17Å; Q296-C299 PolarHBondContact O-N 3.14Å; Q296-C299 VanDerWaalsContact O-N 3.14Å; Q296-C299 PolarHBondContact OE1-SG 2.78Å; L297-C299 VanDerWaalsContact C-N 3.32Å; L297-C299 PolarHBondContact O-N 3.33Å
300L53.9Low79.6Confident22 Ų2240.3 Ų40.312%0.11520%0.196CC..  trans-146.898-164.2-71.4171.2000113.2K133 Y291 E298 D302 A303K133-L300 HydrophobicContact CG-CD2 3.93Å; Y291-L300 HydrophobicContact CD1-CD1 3.72Å; Y291-L300 HydrophobicContact CD2-CD1 3.43Å; Y291-L300 VanDerWaalsContact CD2-CD1 3.43Å; Y291-L300 HydrophobicContact CE1-CD1 3.26Å; Y291-L300 HydrophobicContact CE2-CD1 2.94Å; Y291-L300 HydrophobicContact CE2-CG 4.31Å; Y291-L300 HydrophobicContact CG-CD1 3.81Å; Y291-L300 WeakPolarHBondContact OH-CD1 3.38Å; E298-L300 PolarHBondContact O-N 3.03Å; E298-L300 VanDerWaalsContact O-N 3.14Å; L300-D302 HydrophobicContact CB-CB 3.73Å; L300-D302 HydrophobicContact CD1-CB 4.48Å; L300-D302 HydrophobicContact CD2-CB 3.7Å; L300-D302 HydrophobicContact CG-CB 4.15Å; L300-D302 PolarHBondContact O-N 3.39Å; L300-A303 PolarHBondContact O-N 3.44Å
301D59.8Low79.6Confident126 Ų12642 Ų4267%0.67420%0.204SC*.THydrogen-bonded Turntrans-51.3-8146.9-59.1-42.8000112
302D73.8Confident79.7Confident8 Ų847.7 Ų47.74%0.04323%0.229CC..Hα-helixtrans-73.9-33.2169.9-154.125.5000114.2K133 L300 E304 K305 K306K133-D302 HydrophobicContact CD-CB 4.04Å; K133-D302 WeakPolarHBondContact CD-OD1 3.47Å; K133-D302 WeakPolarHBondContact CD-OD2 3.32Å; K133-D302 WeakPolarHBondContact CE-OD1 3.33Å; K133-D302 HydrophobicContact CG-CB 4Å; K133-D302 WeakPolarHBondContact CG-OD2 3.3Å; K133-D302 VanDerWaalsContact NZ-CG 3.32Å; K133-D302 IonicContact NZ-OD1 3.84Å; K133-D302 PolarHBondContact NZ-OD1 3.42Å; K133-D302 IonicContact NZ-OD2 2.61Å; L300-D302 HydrophobicContact CB-CB 3.73Å; L300-D302 HydrophobicContact CD1-CB 4.48Å; L300-D302 HydrophobicContact CD2-CB 3.7Å; L300-D302 HydrophobicContact CG-CB 4.15Å; L300-D302 PolarHBondContact O-N 3.39Å; D302-E304 VanDerWaalsContact C-N 3.3Å; D302-E304 PolarHBondContact O-N 2.97Å; D302-K305 CarbonylContact O-C 3.58Å; D302-K305 WeakPolarHBondContact O-CA 3.42Å; D302-K305 WeakPolarHBondContact O-CB 3.34Å; D302-K305 PolarHBondContact O-N 3.43Å; D302-K306 WeakPolarHBondContact O-CB 3.38Å; D302-K306 WeakPolarHBondContact O-CG 3.31Å; D302-K306 PolarHBondContact O-N 3.12Å; D302-K306 WeakPolarHBondContact OD2-CE 3.19Å; D302-K306 IonicContact OD2-NZ 2.67Å; D302-K306 PolarHBondContact OD2-NZ 2.91Å
303A83.6Confident79.8Confident5 Ų546.7 Ų46.74%0.04122%0.224CC..Hα-helixtrans-60.1-42.1-172.700000111.6V288 L300 K306 L307V288-A303 HydrophobicContact CG1-CB 4.35Å; V288-A303 HydrophobicContact CG2-CB 4.34Å; L300-A303 PolarHBondContact O-N 3.44Å; A303-K306 PolarHBondContact O-N 3.39Å; A303-L307 WeakPolarHBondContact O-CB 3.32Å; A303-L307 VanDerWaalsContact O-CG 3.22Å; A303-L307 WeakPolarHBondContact O-CG 3.42Å; A303-L307 PolarHBondContact O-N 2.95Å
304E85.3Confident79.9Confident80 Ų8043.5 Ų43.537%0.37421%0.212SC..Hα-helixtrans-62-45.4172.9178.8176.3-161.100112.4D302 K306 L307 N308 R349D302-E304 VanDerWaalsContact C-N 3.3Å; D302-E304 PolarHBondContact O-N 2.97Å; E304-K306 VanDerWaalsContact C-N 3.33Å; E304-K306 PolarHBondContact O-N 3.27Å; E304-L307 PolarHBondContact O-N 3.41Å; E304-N308 WeakPolarHBondContact O-CB 3.44Å; E304-N308 PolarHBondContact O-N 3.07Å; E304-N308 PolarHBondContact O-ND2 2.86Å; E304-R349 IonicContact OE1-CZ 2.74Å; E304-R349 IonicContact OE1-NH2 3.47Å; E304-R349 PolarHBondContact OE1-NH2 3.28Å; E304-R349 IonicContact OE2-CZ 3.83Å; E304-R349 IonicContact OE2-NE 3.5Å; E304-R349 IonicContact OE2-NH2 3.51Å; E304-R349 PolarHBondContact OE2-NH2 2.76Å
305K88.1Confident80.1Confident132 Ų13246.9 Ų46.957%0.57423%0.226SC*.Hα-helixtrans-62.5-42.8179.1-66.7178-178.5177.80111.1D302 N308 L309D302-K305 CarbonylContact O-C 3.58Å; D302-K305 WeakPolarHBondContact O-CA 3.42Å; D302-K305 WeakPolarHBondContact O-CB 3.34Å; D302-K305 PolarHBondContact O-N 3.43Å; K305-N308 PolarHBondContact O-N 3.44Å; K305-L309 VanDerWaalsContact O-CB 3.28Å; K305-L309 WeakPolarHBondContact O-CB 3.39Å; K305-L309 PolarHBondContact O-N 3.27Å
306K90.3Very high80.4Confident8 Ų846.2 Ų46.24%0.03523%0.225CC..Hα-helixtrans-63.6-45.5176.6-70.4-163.8171.4-45.90111.6D263 Q284 I287 V288 Y291 D302 A303 E304 L309 A310D263-K306 IonicContact OD1-NZ 2.91Å; D263-K306 IonicContact OD2-NZ 2.98Å; D263-K306 PolarHBondContact OD2-NZ 3.39Å; Q284-K306 HydrophobicContact CB-CB 4.15Å; I287-K306 HydrophobicContact CB-CD 4.3Å; I287-K306 HydrophobicContact CG2-CD 3.83Å; V288-K306 HydrophobicContact CG2-CB 3.78Å; V288-K306 HydrophobicContact CG2-CD 4.25Å; Y291-K306 HydrophobicContact CE2-CD 4.5Å; D302-K306 WeakPolarHBondContact O-CB 3.38Å; D302-K306 WeakPolarHBondContact O-CG 3.31Å; D302-K306 PolarHBondContact O-N 3.12Å; D302-K306 WeakPolarHBondContact OD2-CE 3.19Å; D302-K306 IonicContact OD2-NZ 2.67Å; D302-K306 PolarHBondContact OD2-NZ 2.91Å; A303-K306 PolarHBondContact O-N 3.39Å; E304-K306 VanDerWaalsContact C-N 3.33Å; E304-K306 PolarHBondContact O-N 3.27Å; K306-L309 PolarHBondContact O-N 3.25Å; K306-A310 WeakPolarHBondContact O-CB 3.38Å; K306-A310 PolarHBondContact O-N 3.01Å
307L92Very high80.8Confident2 Ų246.5 Ų46.51%0.0123%0.227CC..Hα-helixtrans-64.8-41.7176.2-69.7171.6000112.3L285 V288 A303 E304 A310 Q311 L342 L345 Q346 R349L285-L307 HydrophobicContact CD2-CD2 3.91Å; V288-L307 HydrophobicContact CB-CD2 4.35Å; V288-L307 HydrophobicContact CG1-CD1 4.22Å; V288-L307 HydrophobicContact CG1-CD2 4.08Å; V288-L307 HydrophobicContact CG1-CG 4.15Å; V288-L307 HydrophobicContact CG2-CD2 4.39Å; V288-L307 HydrophobicContact CG2-CG 4.26Å; A303-L307 WeakPolarHBondContact O-CB 3.32Å; A303-L307 VanDerWaalsContact O-CG 3.22Å; A303-L307 WeakPolarHBondContact O-CG 3.42Å; A303-L307 PolarHBondContact O-N 2.95Å; E304-L307 PolarHBondContact O-N 3.41Å; L307-A310 PolarHBondContact O-N 3.11Å; L307-Q311 WeakPolarHBondContact O-CB 3.43Å; L307-Q311 PolarHBondContact O-N 2.77Å; L307-L342 HydrophobicContact CB-CD1 4.4Å; L307-L342 HydrophobicContact CD2-CD1 3.96Å; L307-L345 HydrophobicContact CD1-CB 4.27Å; L307-L345 HydrophobicContact CD2-CB 3.75Å; L307-L345 HydrophobicContact CD2-CD1 4.24Å; L307-Q346 HydrophobicContact CB-CG 4.2Å; L307-Q346 HydrophobicContact CD1-CG 4.06Å; L307-R349 HydrophobicContact CD1-CB 4.33Å
308N90.9Very high81.5Confident79 Ų7945.2 Ų45.242%0.42222%0.221SC..Hα-helixtrans-66.1-39.1176.6-71.9-17.9000111.7E304 K305 Q311 K312E304-N308 WeakPolarHBondContact O-CB 3.44Å; E304-N308 PolarHBondContact O-N 3.07Å; E304-N308 PolarHBondContact O-ND2 2.86Å; K305-N308 PolarHBondContact O-N 3.44Å; N308-Q311 PolarHBondContact O-N 3.16Å; N308-K312 WeakPolarHBondContact O-CB 3.46Å; N308-K312 PolarHBondContact O-N 2.97Å
309L90.3Very high82.6Confident59 Ų5942.7 Ų42.731%0.30921%0.214SC..Hα-helixtrans-63.2-49.2174.1-170.9146.9000110.7Y280 Q284 K305 K306 Q311 K312 C313Y280-L309 HydrophobicContact CD1-CD2 3.64Å; Y280-L309 HydrophobicContact CE1-CD1 3.92Å; Y280-L309 HydrophobicContact CE1-CD2 3.37Å; Y280-L309 HydrophobicContact CE1-CG 4.29Å; Q284-L309 HydrophobicContact CG-CD2 3.76Å; K305-L309 VanDerWaalsContact O-CB 3.28Å; K305-L309 WeakPolarHBondContact O-CB 3.39Å; K305-L309 PolarHBondContact O-N 3.27Å; K306-L309 PolarHBondContact O-N 3.25Å; L309-Q311 VanDerWaalsContact C-N 3.32Å; L309-Q311 PolarHBondContact O-N 2.73Å; L309-K312 PolarHBondContact O-N 2.98Å; L309-C313 WeakPolarHBondContact O-CB 3.46Å; L309-C313 PolarHBondContact O-N 3.49Å; L309-C313 PolarHBondContact O-SG 2.93Å; L309-C313 VanDerWaalsContact O-SG 3.41Å
310A92.5Very high83.5Confident0 Ų049.8 Ų49.80%025%0.245CC..Hα-helixtrans-56.7-47176.900000111.3A281 Q284 L285 K306 L307 K312 C313 F314 L342A281-A310 HydrophobicContact CB-CB 4.32Å; Q284-A310 HydrophobicContact CB-CB 4.18Å; L285-A310 HydrophobicContact CD2-CB 4.07Å; L285-A310 HydrophobicContact CG-CB 4.18Å; K306-A310 WeakPolarHBondContact O-CB 3.38Å; K306-A310 PolarHBondContact O-N 3.01Å; L307-A310 PolarHBondContact O-N 3.11Å; A310-K312 VanDerWaalsContact C-N 3.35Å; A310-K312 PolarHBondContact O-N 2.92Å; A310-C313 PolarHBondContact O-N 3.37Å; A310-F314 HydrophobicContact CB-CD2 4.49Å; A310-F314 HydrophobicContact CB-CE2 4.01Å; A310-F314 WeakPolarHBondContact O-CD2 3.41Å; A310-F314 VanDerWaalsContact O-CG 3.26Å; A310-F314 WeakPolarHBondContact O-CG 3.35Å; A310-F314 PolarHBondContact O-N 2.72Å; A310-L342 HydrophobicContact CB-CD1 4.38Å
311Q91.7Very high84.4Confident34 Ų3454.1 Ų54.116%0.15927%0.268CS..Hα-helixtrans-60-42.9177.4-172.3173.920.800112.5L307 N308 L309 K315 L342L307-Q311 WeakPolarHBondContact O-CB 3.43Å; L307-Q311 PolarHBondContact O-N 2.77Å; N308-Q311 PolarHBondContact O-N 3.16Å; L309-Q311 VanDerWaalsContact C-N 3.32Å; L309-Q311 PolarHBondContact O-N 2.73Å; Q311-K315 WeakPolarHBondContact O-CG 3.34Å; Q311-K315 PolarHBondContact O-N 3.49Å; Q311-L342 HydrophobicContact CB-CD1 4.38Å; Q311-L342 HydrophobicContact CB-CD2 3.87Å; Q311-L342 HydrophobicContact CG-CD2 4.01Å
312K90.3Very high85.3Confident122 Ų12249.9 Ų49.953%0.5325%0.245SC..Hα-helixtrans-63.8-48.1176.9-175.9-173.8174-1630111N308 L309 A310 F314 K315 N316N308-K312 WeakPolarHBondContact O-CB 3.46Å; N308-K312 PolarHBondContact O-N 2.97Å; L309-K312 PolarHBondContact O-N 2.98Å; A310-K312 VanDerWaalsContact C-N 3.35Å; A310-K312 PolarHBondContact O-N 2.92Å; K312-F314 PolarHBondContact O-N 3.2Å; K312-K315 PolarHBondContact O-N 3.34Å; K312-N316 VanDerWaalsContact O-CG 3.31Å; K312-N316 PolarHBondContact O-N 3.04Å; K312-N316 PolarHBondContact O-OD1 3.32Å
313C89.3Confident85.4Confident4 Ų455.7 Ų55.73%0.02727%0.272CS..Hα-helixtrans-61.6-44.1179.1-71.50000111.6A281 L309 A310 K315 N316 C317A281-C313 HydrophobicContact CB-CB 3.53Å; L309-C313 WeakPolarHBondContact O-CB 3.46Å; L309-C313 PolarHBondContact O-N 3.49Å; L309-C313 PolarHBondContact O-SG 2.93Å; L309-C313 VanDerWaalsContact O-SG 3.41Å; A310-C313 PolarHBondContact O-N 3.37Å; C313-K315 PolarHBondContact O-N 2.68Å; C313-N316 PolarHBondContact O-N 3.25Å; C313-C317 WeakPolarHBondContact O-CB 3.32Å; C313-C317 PolarHBondContact O-N 2.9Å; C313-C317 PolarHBondContact O-SG 2.78Å
314F88.9Confident85.1Confident0 Ų060.5 Ų60.50%029%0.289CS..Hα-helixtrans-62.7-40.6175.7-65.4-39000112.7D278 A281 V282 L285 A310 K312 N316 C317 Y318 L338 F339 L342D278-F314 HydrophobicContact CB-CD1 4.38Å; D278-F314 HydrophobicContact CB-CE1 4.35Å; A281-F314 HydrophobicContact CB-CD1 3.76Å; A281-F314 HydrophobicContact CB-CE1 3.39Å; A281-F314 HydrophobicContact CB-CE2 4.29Å; A281-F314 HydrophobicContact CB-CG 4.37Å; A281-F314 HydrophobicContact CB-CZ 3.68Å; V282-F314 HydrophobicContact CG2-CE1 4Å; V282-F314 HydrophobicContact CG2-CZ 4.22Å; L285-F314 HydrophobicContact CD1-CE2 3.55Å; L285-F314 HydrophobicContact CD1-CZ 3.6Å; L285-F314 HydrophobicContact CD2-CE2 4.49Å; L285-F314 HydrophobicContact CG-CE2 3.98Å; L285-F314 HydrophobicContact CG-CZ 4.11Å; A310-F314 HydrophobicContact CB-CD2 4.49Å; A310-F314 HydrophobicContact CB-CE2 4.01Å; A310-F314 WeakPolarHBondContact O-CD2 3.41Å; A310-F314 VanDerWaalsContact O-CG 3.26Å; A310-F314 WeakPolarHBondContact O-CG 3.35Å; A310-F314 PolarHBondContact O-N 2.72Å; K312-F314 PolarHBondContact O-N 3.2Å; F314-N316 VanDerWaalsContact C-N 3.32Å; F314-N316 PolarHBondContact O-N 2.83Å; F314-C317 PolarHBondContact O-N 2.85Å; F314-Y318 HydrophobicContact CB-CD2 3.87Å; F314-Y318 HydrophobicContact CB-CE2 3.96Å; F314-Y318 HydrophobicContact CD1-CD2 4.16Å; F314-Y318 AromaticContact CD1-CE2 3.38Å; F314-Y318 HydrophobicContact CD1-CE2 3.38Å; F314-Y318 HydrophobicContact CE1-CE2 4.15Å; F314-Y318 HydrophobicContact CG-CD2 4.34Å; F314-Y318 AromaticContact CG-CE2 3.92Å; F314-Y318 HydrophobicContact CG-CE2 3.92Å; F314-Y318 WeakPolarHBondContact O-CB 3.25Å; F314-Y318 WeakPolarHBondContact O-CD2 3.47Å; F314-Y318 PolarHBondContact O-N 3.15Å; F314-L338 HydrophobicContact CE1-CD1 3.95Å; F314-L338 HydrophobicContact CZ-CB 4.19Å; F314-L338 HydrophobicContact CZ-CD1 4.29Å; F314-F339 HydrophobicContact CB-CE1 4.05Å; F314-F339 HydrophobicContact CB-CE2 4.43Å; F314-F339 HydrophobicContact CB-CZ 3.74Å; F314-F339 HydrophobicContact CG-CZ 4.48Å; F314-L342 HydrophobicContact CD2-CD2 4.15Å
315K87.4Confident84.5Confident101 Ų10156.8 Ų56.844%0.43927%0.271SS..Hα-helixtrans-61.1-41173.8-76.4-179.9177.9-171.70112Q311 K312 C313 G319Q311-K315 WeakPolarHBondContact O-CG 3.34Å; Q311-K315 PolarHBondContact O-N 3.49Å; K312-K315 PolarHBondContact O-N 3.34Å; C313-K315 PolarHBondContact O-N 2.68Å; K315-G319 CarbonylContact O-C 3.59Å; K315-G319 WeakPolarHBondContact O-CA 3.38Å; K315-G319 PolarHBondContact O-N 3.42Å
316N84.9Confident83.9Confident70 Ų7053.5 Ų53.537%0.37426%0.262SS..Hα-helixtrans-67.9-42.8177-69.4-4.8000112K312 C313 F314 R324K312-N316 VanDerWaalsContact O-CG 3.31Å; K312-N316 PolarHBondContact O-N 3.04Å; K312-N316 PolarHBondContact O-OD1 3.32Å; C313-N316 PolarHBondContact O-N 3.25Å; F314-N316 VanDerWaalsContact C-N 3.32Å; F314-N316 PolarHBondContact O-N 2.83Å; N316-R324 PolarHBondContact O-NH1 3Å
317C81.1Confident82.8Confident10 Ų1061.2 Ų61.27%0.06830%0.298CS..Hα-helixtrans-73.7-44.4-176.1-66.10000112.2D278 C313 F314 R324D278-C317 HydrophobicContact CB-CB 4.31Å; C313-C317 WeakPolarHBondContact O-CB 3.32Å; C313-C317 PolarHBondContact O-N 2.9Å; C313-C317 PolarHBondContact O-SG 2.78Å; F314-C317 PolarHBondContact O-N 2.85Å; C317-R324 VanDerWaalsContact O-CD 3.3Å; C317-R324 WeakPolarHBondContact O-CD 3.25Å; C317-R324 PolarHBondContact O-NH1 2.95Å
318Y82.6Confident81.6Confident3 Ų363.8 Ų63.81%0.01231%0.311CS..Hα-helixtrans-101.5-16.3-172.7-49.8-41.9000113.6D278 F314 H322 Q323 R324 L325 E335 L338 F339D278-Y318 HydrophobicContact CB-CE1 4.2Å; D278-Y318 VanDerWaalsContact CB-OH 3.27Å; D278-Y318 WeakPolarHBondContact CB-OH 3.42Å; D278-Y318 VanDerWaalsContact CG-OH 3.29Å; D278-Y318 WeakPolarHBondContact OD2-CE1 3.31Å; D278-Y318 VanDerWaalsContact OD2-CZ 3.31Å; D278-Y318 PolarHBondContact OD2-OH 2.85Å; F314-Y318 HydrophobicContact CB-CD2 3.87Å; F314-Y318 HydrophobicContact CB-CE2 3.96Å; F314-Y318 HydrophobicContact CD1-CD2 4.16Å; F314-Y318 AromaticContact CD1-CE2 3.38Å; F314-Y318 HydrophobicContact CD1-CE2 3.38Å; F314-Y318 HydrophobicContact CE1-CE2 4.15Å; F314-Y318 HydrophobicContact CG-CD2 4.34Å; F314-Y318 AromaticContact CG-CE2 3.92Å; F314-Y318 HydrophobicContact CG-CE2 3.92Å; F314-Y318 WeakPolarHBondContact O-CB 3.25Å; F314-Y318 WeakPolarHBondContact O-CD2 3.47Å; F314-Y318 PolarHBondContact O-N 3.15Å; Y318-H322 CarbonylContact O-C 3.59Å; Y318-H322 WeakPolarHBondContact O-CA 3.29Å; Y318-Q323 PolarHBondContact O-N 3.46Å; Y318-R324 WeakPolarHBondContact O-CB 3.45Å; Y318-R324 PolarHBondContact O-N 3.07Å; Y318-L325 HydrophobicContact CD1-CB 4.17Å; Y318-L325 HydrophobicContact CD1-CD1 4.02Å; Y318-L325 HydrophobicContact CD1-CD2 4.09Å; Y318-L325 HydrophobicContact CD1-CG 4.34Å; Y318-L325 HydrophobicContact CE1-CD1 4.33Å; Y318-L325 HydrophobicContact CG-CB 4.46Å; Y318-L325 HydrophobicContact CG-CD2 4.3Å; Y318-L325 PolarHBondContact O-N 2.88Å; Y318-E335 HydrophobicContact CE1-CG 4.44Å; Y318-L338 HydrophobicContact CE2-CD1 4.32Å; Y318-L338 VanDerWaalsContact OH-CD1 3.27Å; Y318-L338 WeakPolarHBondContact OH-CD1 3.2Å; Y318-F339 AromaticContact CD2-CE2 3.47Å; Y318-F339 HydrophobicContact CD2-CE2 3.47Å; Y318-F339 VanDerWaalsContact CD2-CE2 3.47Å; Y318-F339 AromaticContact CD2-CZ 3.67Å; Y318-F339 HydrophobicContact CD2-CZ 3.67Å; Y318-F339 AromaticContact CE2-CE2 3.88Å; Y318-F339 HydrophobicContact CE2-CE2 3.88Å; Y318-F339 HydrophobicContact CE2-CZ 4.34Å
319G80.2Confident80.4Confident18 Ų1862.4 Ų62.419%0.18630%0.301CS..  trans86159.9-172.300000112.2K315 N321 H322K315-G319 CarbonylContact O-C 3.59Å; K315-G319 WeakPolarHBondContact O-CA 3.38Å; K315-G319 PolarHBondContact O-N 3.42Å; G319-N321 PolarHBondContact O-N 3.11Å; G319-N321 VanDerWaalsContact O-N 3.11Å; G319-H322 PolarHBondContact O-N 2.87Å
320E77.2Confident79.3Confident163 Ų16362.6 Ų62.676%0.76232%0.317SS*.THydrogen-bonded Turntrans-55.9-33.8-173.4-65.9-169.1155.300113.9
321N73.2Confident78.3Confident112 Ų11263.8 Ų63.860%0.59932%0.324SS*.THydrogen-bonded Turntrans-12131.7177.2-63-49.3000112.1G319 Q323G319-N321 PolarHBondContact O-N 3.11Å; G319-N321 VanDerWaalsContact O-N 3.11Å; N321-Q323 HydrophobicContact CB-CG 4.12Å; N321-Q323 PolarHBondContact O-N 2.76Å; N321-Q323 VanDerWaalsContact O-N 3.1Å
322H77.6Confident77.4Confident37 Ų3763.4 Ų63.417%0.17132%0.324CS..SBendtrans62.314.2-176.6-43.291.5000114.5Y318 G319 R324 L325 V326 C332 F339Y318-H322 CarbonylContact O-C 3.59Å; Y318-H322 WeakPolarHBondContact O-CA 3.29Å; G319-H322 PolarHBondContact O-N 2.87Å; H322-R324 VanDerWaalsContact C-N 3.33Å; H322-R324 PolarHBondContact O-N 3.43Å; H322-L325 WeakPolarHBondContact O-CB 3.37Å; H322-L325 PolarHBondContact O-N 2.78Å; H322-V326 WeakPolarHBondContact O-CG2 3.19Å; H322-V326 PolarHBondContact O-N 3.4Å; H322-C332 HydrophobicContact CB-CB 4.04Å; H322-F339 AromaticContact CD2-CE2 3.44Å; H322-F339 VanDerWaalsContact CD2-CE2 3.44Å; H322-F339 WeakPolarHBondContact CD2-CE2 3.38Å; H322-F339 AromaticContact CD2-CZ 3.75Å; H322-F339 AromaticContact NE2-CD2 3.44Å; H322-F339 WeakPolarHBondContact NE2-CD2 3.46Å; H322-F339 AromaticContact NE2-CE1 3.87Å; H322-F339 AromaticContact NE2-CE2 3.1Å; H322-F339 WeakPolarHBondContact NE2-CE2 3.39Å; H322-F339 AromaticContact NE2-CG 3.93Å; H322-F339 AromaticContact NE2-CZ 3.31Å; H322-F339 VanDerWaalsContact NE2-CZ 3.31Å; H322-F339 WeakPolarHBondContact NE2-CZ 3.31Å
323Q76.9Confident76.7Confident131 Ų13158 Ų5861%0.61230%0.303SS*.Hα-helixtrans-61.7-39.1-174.5-68.4163.8-7.400112.5Y318 N321 H327Y318-Q323 PolarHBondContact O-N 3.46Å; N321-Q323 HydrophobicContact CB-CG 4.12Å; N321-Q323 PolarHBondContact O-N 2.76Å; N321-Q323 VanDerWaalsContact O-N 3.1Å; Q323-H327 WeakPolarHBondContact O-CB 3.46Å; Q323-H327 PolarHBondContact O-N 2.83Å
324R75.9Confident76.4Confident106 Ų10658.2 Ų58.240%0.430%0.304SS..Hα-helixtrans-68-39.5178.2179.9175.2173.9-145.6-5.1110.8N316 C317 Y318 H322 H327 I328N316-R324 PolarHBondContact O-NH1 3Å; C317-R324 VanDerWaalsContact O-CD 3.3Å; C317-R324 WeakPolarHBondContact O-CD 3.25Å; C317-R324 PolarHBondContact O-NH1 2.95Å; Y318-R324 WeakPolarHBondContact O-CB 3.45Å; Y318-R324 PolarHBondContact O-N 3.07Å; H322-R324 VanDerWaalsContact C-N 3.33Å; H322-R324 PolarHBondContact O-N 3.43Å; R324-H327 PolarHBondContact O-N 3.11Å; R324-I328 HydrophobicContact CG-CD1 3.71Å; R324-I328 WeakPolarHBondContact O-CD1 3.31Å; R324-I328 VanDerWaalsContact O-CG1 3.24Å; R324-I328 WeakPolarHBondContact O-CG1 3.06Å; R324-I328 PolarHBondContact O-N 3.47Å; R324-I328 VanDerWaalsContact O-N 3.1Å
325L73.8Confident76.3Confident2 Ų258.2 Ų58.21%0.0130%0.304CS..Hα-helixtrans-64.1-47176.7-177.964.7000111.5Y318 H322 H327 I328 K329 C332 E335Y318-L325 HydrophobicContact CD1-CB 4.17Å; Y318-L325 HydrophobicContact CD1-CD1 4.02Å; Y318-L325 HydrophobicContact CD1-CD2 4.09Å; Y318-L325 HydrophobicContact CD1-CG 4.34Å; Y318-L325 HydrophobicContact CE1-CD1 4.33Å; Y318-L325 HydrophobicContact CG-CB 4.46Å; Y318-L325 HydrophobicContact CG-CD2 4.3Å; Y318-L325 PolarHBondContact O-N 2.88Å; H322-L325 WeakPolarHBondContact O-CB 3.37Å; H322-L325 PolarHBondContact O-N 2.78Å; L325-H327 VanDerWaalsContact C-N 3.29Å; L325-H327 PolarHBondContact O-N 3.46Å; L325-I328 PolarHBondContact O-N 3.24Å; L325-I328 VanDerWaalsContact O-N 3.15Å; L325-K329 HydrophobicContact CD1-CD 4.07Å; L325-K329 HydrophobicContact CD1-CG 4.34Å; L325-K329 PolarHBondContact O-N 3.44Å; L325-C332 HydrophobicContact CD2-CB 3.58Å; L325-C332 HydrophobicContact CG-CB 4.06Å; L325-E335 HydrophobicContact CD1-CG 4.09Å; L325-E335 HydrophobicContact CD2-CB 3.51Å; L325-E335 HydrophobicContact CD2-CG 3.57Å; L325-E335 HydrophobicContact CG-CG 4.45Å
326V74.9Confident76.4Confident63 Ų6355.4 Ų55.438%0.38229%0.292SS..Hα-helixtrans-59.6-40.1174.7175.10000111.2H322 I328 G330 C332H322-V326 WeakPolarHBondContact O-CG2 3.19Å; H322-V326 PolarHBondContact O-N 3.4Å; V326-I328 VanDerWaalsContact C-N 3.3Å; V326-I328 PolarHBondContact O-N 2.93Å; V326-G330 WeakPolarHBondContact O-CA 3.37Å; V326-G330 PolarHBondContact O-N 2.79Å; V326-C332 HydrophobicContact CG2-CB 3.8Å
327H67.4Low76.7Confident169 Ų16952.4 Ų52.478%0.78228%0.276SS*.Hα-helixtrans-64.5-33.7177.8-174.962.6000113.3Q323 R324 L325Q323-H327 WeakPolarHBondContact O-CB 3.46Å; Q323-H327 PolarHBondContact O-N 2.83Å; R324-H327 PolarHBondContact O-N 3.11Å; L325-H327 VanDerWaalsContact C-N 3.29Å; L325-H327 PolarHBondContact O-N 3.46Å
328I66.2Low77.2Confident56 Ų5652.5 Ų52.529%0.28728%0.276SS..Hα-helixtrans-86-47.5-176-69.1164.7000111.9Q218 R324 L325 V326Q218-I328 HydrophobicContact CG-CG2 3.94Å; Q218-I328 VanDerWaalsContact NE2-CG2 3.32Å; R324-I328 HydrophobicContact CG-CD1 3.71Å; R324-I328 WeakPolarHBondContact O-CD1 3.31Å; R324-I328 VanDerWaalsContact O-CG1 3.24Å; R324-I328 WeakPolarHBondContact O-CG1 3.06Å; R324-I328 PolarHBondContact O-N 3.47Å; R324-I328 VanDerWaalsContact O-N 3.1Å; L325-I328 PolarHBondContact O-N 3.24Å; L325-I328 VanDerWaalsContact O-N 3.15Å; V326-I328 VanDerWaalsContact C-N 3.3Å; V326-I328 PolarHBondContact O-N 2.93Å
329K66.8Low77.7Confident51 Ų5153 Ų5322%0.22228%0.277CS..Hα-helixtrans-102.7-11.5-173.4-71.7-165.9177.6-173.90113.9L325 N331 E335 E570L325-K329 HydrophobicContact CD1-CD 4.07Å; L325-K329 HydrophobicContact CD1-CG 4.34Å; L325-K329 PolarHBondContact O-N 3.44Å; K329-N331 PolarHBondContact O-N 2.93Å; K329-E335 WeakPolarHBondContact CD-OE1 3.36Å; K329-E335 WeakPolarHBondContact CE-OE1 3.49Å; K329-E335 IonicContact NZ-OE1 2.56Å; K329-E335 PolarHBondContact NZ-OE1 3.1Å; K329-E570 IonicContact NZ-OE1 3.33Å; K329-E570 PolarHBondContact NZ-OE1 3.06Å
330G66.4Low78.3Confident62 Ų6252.1 Ų52.164%0.63927%0.269SS*.SBendtrans77.4-12.2-174.200000114.5V326V326-G330 WeakPolarHBondContact O-CA 3.37Å; V326-G330 PolarHBondContact O-N 2.79Å
331N71.6Confident79.2Confident26 Ų2646.6 Ų46.614%0.13924%0.241CC..  trans-143.3166.6174.563.358.8000110.5K329 A399 H410K329-N331 PolarHBondContact O-N 2.93Å; N331-A399 HydrophobicContact CB-CB 4.44Å; N331-H410 PolarHBondContact ND2-NE2 2.96Å
332C72.6Confident80.2Confident25 Ų2541.3 Ų41.317%0.16921%0.212CC..  trans-138.14.8177.1640000113.5H322 L325 V326 K334 E335 K336H322-C332 HydrophobicContact CB-CB 4.04Å; L325-C332 HydrophobicContact CD2-CB 3.58Å; L325-C332 HydrophobicContact CG-CB 4.06Å; V326-C332 HydrophobicContact CG2-CB 3.8Å; C332-K334 VanDerWaalsContact C-N 3.28Å; C332-K334 PolarHBondContact O-N 3.45Å; C332-E335 PolarHBondContact O-N 3.37Å; C332-K336 PolarHBondContact O-N 3.45Å
333G75.4Confident81.1Confident8 Ų841.7 Ų41.78%0.08221%0.213CC..THydrogen-bonded Turntrans-65.2-30.9-170.100000113.3L373 R398G333-L373 WeakPolarHBondContact O-CD2 3.33Å; G333-R398 WeakPolarHBondContact CA-O 3.47Å
334K83.1Confident82Confident9 Ų935.4 Ų35.44%0.03918%0.184CC..THydrogen-bonded Turntrans-73.5-44.9-178.7-59.1171.5177.6-179.20111.8C332 K336 V337 L395 R398 A399 E570 L573C332-K334 VanDerWaalsContact C-N 3.28Å; C332-K334 PolarHBondContact O-N 3.45Å; K334-K336 VanDerWaalsContact C-N 3.27Å; K334-K336 PolarHBondContact O-N 2.96Å; K334-V337 WeakPolarHBondContact O-CB 3.43Å; K334-V337 WeakPolarHBondContact O-CG2 3.43Å; K334-V337 PolarHBondContact O-N 3.29Å; K334-L395 HydrophobicContact CD-CB 4.25Å; K334-L395 HydrophobicContact CD-CD2 4.37Å; K334-L395 WeakPolarHBondContact CE-O 3.45Å; K334-L395 HydrophobicContact CG-CD2 4.36Å; K334-L395 WeakPolarHBondContact CG-O 3.4Å; K334-R398 HydrophobicContact CG-CB 4.13Å; K334-A399 HydrophobicContact CD-CB 4.4Å; K334-A399 HydrophobicContact CG-CB 4.26Å; K334-E570 IonicContact NZ-OE2 2.85Å; K334-E570 PolarHBondContact NZ-OE2 3.38Å; K334-L573 HydrophobicContact CB-CD1 4.04Å
335E87.6Confident82.9Confident0 Ų030.5 Ų30.50%017%0.165CC..THydrogen-bonded Turntrans-70.9-21.5-175.5-66.278.3-179.100112.8Y318 L325 K329 C332 V337 L338 L573Y318-E335 HydrophobicContact CE1-CG 4.44Å; L325-E335 HydrophobicContact CD1-CG 4.09Å; L325-E335 HydrophobicContact CD2-CB 3.51Å; L325-E335 HydrophobicContact CD2-CG 3.57Å; L325-E335 HydrophobicContact CG-CG 4.45Å; K329-E335 WeakPolarHBondContact CD-OE1 3.36Å; K329-E335 WeakPolarHBondContact CE-OE1 3.49Å; K329-E335 IonicContact NZ-OE1 2.56Å; K329-E335 PolarHBondContact NZ-OE1 3.1Å; C332-E335 PolarHBondContact O-N 3.37Å; E335-V337 PolarHBondContact O-N 3.38Å; E335-V337 VanDerWaalsContact O-N 3.08Å; E335-L338 WeakPolarHBondContact O-CB 3.43Å; E335-L338 PolarHBondContact O-N 3.27Å; E335-L573 HydrophobicContact CG-CD1 4.1Å
336K88.4Confident83.8Confident43 Ų4330.8 Ų30.819%0.18717%0.166CC..Hα-helixtrans-54.8-24.4171.6-77-178.8176.2-1710113C332 K334 L338 F339 L340 L369 E372 L373C332-K336 PolarHBondContact O-N 3.45Å; K334-K336 VanDerWaalsContact C-N 3.27Å; K334-K336 PolarHBondContact O-N 2.96Å; K336-L338 PolarHBondContact O-N 3.24Å; K336-F339 PolarHBondContact O-N 2.85Å; K336-F339 VanDerWaalsContact O-N 3.13Å; K336-L340 PolarHBondContact O-N 2.97Å; K336-L369 HydrophobicContact CD-CD2 4.4Å; K336-E372 IonicContact NZ-OE2 2.87Å; K336-E372 PolarHBondContact NZ-OE2 2.9Å; K336-L373 HydrophobicContact CB-CD1 3.91Å; K336-L373 HydrophobicContact CB-CD2 3.82Å; K336-L373 HydrophobicContact CB-CG 4.32Å; K336-L373 HydrophobicContact CD-CD2 4.33Å
337V91.4Very high84.6Confident7 Ų727.8 Ų27.84%0.04215%0.148CC..Hα-helixtrans-57.1-37.6173.2172.40000111.5K334 E335 F339 L340 R341 L373 L577K334-V337 WeakPolarHBondContact O-CB 3.43Å; K334-V337 WeakPolarHBondContact O-CG2 3.43Å; K334-V337 PolarHBondContact O-N 3.29Å; E335-V337 PolarHBondContact O-N 3.38Å; E335-V337 VanDerWaalsContact O-N 3.08Å; V337-F339 PolarHBondContact O-N 2.68Å; V337-L340 WeakPolarHBondContact O-CB 3.42Å; V337-L340 PolarHBondContact O-N 3.18Å; V337-R341 PolarHBondContact O-N 3.43Å; V337-R341 VanDerWaalsContact O-N 3.11Å; V337-L373 HydrophobicContact CG2-CD1 4.03Å; V337-L373 HydrophobicContact CG2-CD2 4.48Å; V337-L577 HydrophobicContact CG1-CD2 4.08Å
338L92.6Very high85.8Confident12 Ų1219.8 Ų19.86%0.06311%0.111CC..Hα-helixtrans-65.9-39.4177.6-57.3176.3000111.6V282 L285 F314 Y318 E335 K336 R341 L342 Y572 L573V282-L338 HydrophobicContact CG2-CD1 3.94Å; V282-L338 HydrophobicContact CG2-CD2 4.13Å; L285-L338 HydrophobicContact CD1-CB 4.44Å; F314-L338 HydrophobicContact CE1-CD1 3.95Å; F314-L338 HydrophobicContact CZ-CB 4.19Å; F314-L338 HydrophobicContact CZ-CD1 4.29Å; Y318-L338 HydrophobicContact CE2-CD1 4.32Å; Y318-L338 VanDerWaalsContact OH-CD1 3.27Å; Y318-L338 WeakPolarHBondContact OH-CD1 3.2Å; E335-L338 WeakPolarHBondContact O-CB 3.43Å; E335-L338 PolarHBondContact O-N 3.27Å; K336-L338 PolarHBondContact O-N 3.24Å; L338-R341 PolarHBondContact O-N 3.39Å; L338-L342 WeakPolarHBondContact O-CB 3.47Å; L338-L342 PolarHBondContact O-N 2.97Å; L338-Y572 HydrophobicContact CD1-CE2 4.19Å; L338-Y572 HydrophobicContact CD2-CD2 4.31Å; L338-Y572 HydrophobicContact CD2-CE2 4.34Å; L338-L573 HydrophobicContact CD1-CD2 3.87Å; L338-L573 HydrophobicContact CD2-CD2 3.97Å; L338-L573 HydrophobicContact CG-CD2 3.75Å
339F92.3Very high86.9Confident12 Ų1219.7 Ų19.75%0.05311%0.107CC..Hα-helixtrans-69.1-37.5176.9-73-89.3000112.4F314 Y318 H322 K336 V337 R341 L342 Y343 L369F314-F339 HydrophobicContact CB-CE1 4.05Å; F314-F339 HydrophobicContact CB-CE2 4.43Å; F314-F339 HydrophobicContact CB-CZ 3.74Å; F314-F339 HydrophobicContact CG-CZ 4.48Å; Y318-F339 AromaticContact CD2-CE2 3.47Å; Y318-F339 HydrophobicContact CD2-CE2 3.47Å; Y318-F339 VanDerWaalsContact CD2-CE2 3.47Å; Y318-F339 AromaticContact CD2-CZ 3.67Å; Y318-F339 HydrophobicContact CD2-CZ 3.67Å; Y318-F339 AromaticContact CE2-CE2 3.88Å; Y318-F339 HydrophobicContact CE2-CE2 3.88Å; Y318-F339 HydrophobicContact CE2-CZ 4.34Å; H322-F339 AromaticContact CD2-CE2 3.44Å; H322-F339 VanDerWaalsContact CD2-CE2 3.44Å; H322-F339 WeakPolarHBondContact CD2-CE2 3.38Å; H322-F339 AromaticContact CD2-CZ 3.75Å; H322-F339 AromaticContact NE2-CD2 3.44Å; H322-F339 WeakPolarHBondContact NE2-CD2 3.46Å; H322-F339 AromaticContact NE2-CE1 3.87Å; H322-F339 AromaticContact NE2-CE2 3.1Å; H322-F339 WeakPolarHBondContact NE2-CE2 3.39Å; H322-F339 AromaticContact NE2-CG 3.93Å; H322-F339 AromaticContact NE2-CZ 3.31Å; H322-F339 VanDerWaalsContact NE2-CZ 3.31Å; H322-F339 WeakPolarHBondContact NE2-CZ 3.31Å; K336-F339 PolarHBondContact O-N 2.85Å; K336-F339 VanDerWaalsContact O-N 3.13Å; V337-F339 PolarHBondContact O-N 2.68Å; F339-R341 VanDerWaalsContact C-N 3.34Å; F339-L342 HydrophobicContact CD1-CD2 4.43Å; F339-L342 PolarHBondContact O-N 2.99Å; F339-Y343 HydrophobicContact CB-CE2 4.19Å; F339-Y343 WeakPolarHBondContact O-CB 3.39Å; F339-Y343 VanDerWaalsContact O-CD2 3.24Å; F339-Y343 WeakPolarHBondContact O-CD2 3.42Å; F339-Y343 VanDerWaalsContact O-CG 3.25Å; F339-Y343 PolarHBondContact O-N 2.96Å; F339-L369 HydrophobicContact CB-CD1 3.88Å
340L94.2Very high88Confident0 Ų018 Ų180%010%0.1CC..Hα-helixtrans-56.4-51.5172.1-176.7163.1000110K336 V337 L342 Y343 L344 L369 F370 L373 L577 E580 I584K336-L340 PolarHBondContact O-N 2.97Å; V337-L340 WeakPolarHBondContact O-CB 3.42Å; V337-L340 PolarHBondContact O-N 3.18Å; L340-L342 PolarHBondContact O-N 3.13Å; L340-Y343 PolarHBondContact O-N 3.28Å; L340-L344 WeakPolarHBondContact O-CB 3.47Å; L340-L344 PolarHBondContact O-N 3.04Å; L340-L369 HydrophobicContact CB-CB 4.09Å; L340-L369 HydrophobicContact CB-CD1 4.22Å; L340-L369 HydrophobicContact CD1-CB 4.26Å; L340-L369 HydrophobicContact CG-CB 4.31Å; L340-F370 VanDerWaalsContact CD1-CA 3.49Å; L340-F370 HydrophobicContact CD1-CB 3.85Å; L340-F370 HydrophobicContact CD1-CD2 4.39Å; L340-L373 HydrophobicContact CB-CD1 4.27Å; L340-L373 HydrophobicContact CD1-CD1 3.94Å; L340-L577 HydrophobicContact CD1-CD1 4.2Å; L340-L577 HydrophobicContact CD1-CD2 4.12Å; L340-L577 HydrophobicContact CD2-CD2 4.4Å; L340-E580 HydrophobicContact CD2-CB 3.82Å; L340-E580 HydrophobicContact CD2-CG 3.72Å; L340-I584 HydrophobicContact CD2-CD1 4.35Å
341R94.9Very high89.1Confident48 Ų4815 Ų1518%0.1817%0.07CC..Hα-helixtrans-66.1-38.4179.9-170161.4-80.1-168.4-8.4112.4W289 V337 L338 F339 L344 L345 E580W289-R341 HydrophobicContact CE3-CG 4.17Å; W289-R341 HydrophobicContact CZ3-CG 4.41Å; V337-R341 PolarHBondContact O-N 3.43Å; V337-R341 VanDerWaalsContact O-N 3.11Å; L338-R341 PolarHBondContact O-N 3.39Å; F339-R341 VanDerWaalsContact C-N 3.34Å; R341-L344 PolarHBondContact O-N 3.28Å; R341-L345 HydrophobicContact CG-CD1 4.21Å; R341-L345 WeakPolarHBondContact O-CB 3.13Å; R341-L345 WeakPolarHBondContact O-CG 3.45Å; R341-L345 PolarHBondContact O-N 3.34Å; R341-E580 IonicContact CZ-OE1 3.79Å; R341-E580 IonicContact NE-OE1 3.64Å; R341-E580 PolarHBondContact NE-OE1 2.88Å; R341-E580 IonicContact NH2-OE1 3.69Å; R341-E580 PolarHBondContact NH2-OE1 3.01Å; R341-E580 IonicContact NH2-OE2 2.75Å; R341-E580 PolarHBondContact NH2-OE2 3.45Å
342L94.8Very high89.7Confident0 Ų015.2 Ų15.20%07%0.07CC..Hα-helixtrans-57.7-53.2172.4174.268.6000111.5L285 L307 A310 Q311 F314 L338 F339 L340 L344 L345 Q346L285-L342 HydrophobicContact CD1-CB 4.43Å; L285-L342 HydrophobicContact CD2-CB 3.95Å; L285-L342 HydrophobicContact CD2-CD1 3.7Å; L285-L342 HydrophobicContact CD2-CG 4.44Å; L307-L342 HydrophobicContact CB-CD1 4.4Å; L307-L342 HydrophobicContact CD2-CD1 3.96Å; A310-L342 HydrophobicContact CB-CD1 4.38Å; Q311-L342 HydrophobicContact CB-CD1 4.38Å; Q311-L342 HydrophobicContact CB-CD2 3.87Å; Q311-L342 HydrophobicContact CG-CD2 4.01Å; F314-L342 HydrophobicContact CD2-CD2 4.15Å; L338-L342 WeakPolarHBondContact O-CB 3.47Å; L338-L342 PolarHBondContact O-N 2.97Å; F339-L342 HydrophobicContact CD1-CD2 4.43Å; F339-L342 PolarHBondContact O-N 2.99Å; L340-L342 PolarHBondContact O-N 3.13Å; L342-L344 VanDerWaalsContact C-N 3.34Å; L342-L344 PolarHBondContact O-N 3.17Å; L342-L345 PolarHBondContact O-N 3.1Å; L342-Q346 HydrophobicContact CD1-CG 4.21Å; L342-Q346 WeakPolarHBondContact O-CB 3.47Å; L342-Q346 VanDerWaalsContact O-CG 3.32Å; L342-Q346 WeakPolarHBondContact O-CG 3.44Å; L342-Q346 PolarHBondContact O-N 3.13Å
343Y95.8Very high90.3Very high45 Ų4516 Ų1618%0.1768%0.076CC..Hα-helixtrans-66.4-36.6-178.2-64.2-31.3000112.2F339 L340 Q346 G347 Y362 K365 L369F339-Y343 HydrophobicContact CB-CE2 4.19Å; F339-Y343 WeakPolarHBondContact O-CB 3.39Å; F339-Y343 VanDerWaalsContact O-CD2 3.24Å; F339-Y343 WeakPolarHBondContact O-CD2 3.42Å; F339-Y343 VanDerWaalsContact O-CG 3.25Å; F339-Y343 PolarHBondContact O-N 2.96Å; L340-Y343 PolarHBondContact O-N 3.28Å; Y343-Q346 PolarHBondContact O-N 3.12Å; Y343-G347 PolarHBondContact O-N 3.32Å; Y343-Y362 AromaticContact CD1-CD1 3.81Å; Y343-Y362 HydrophobicContact CD1-CD1 3.81Å; Y343-Y362 HydrophobicContact CD1-CE1 4.12Å; Y343-Y362 HydrophobicContact CE1-CD1 4.49Å; Y343-Y362 HydrophobicContact CE1-CE1 4.43Å; Y343-Y362 HydrophobicContact CG-CD1 4.4Å; Y343-K365 HydrophobicContact CD2-CB 3.77Å; Y343-K365 HydrophobicContact CE2-CB 4.25Å; Y343-K365 HydrophobicContact CG-CB 4.18Å; Y343-L369 HydrophobicContact CD2-CD1 3.7Å; Y343-L369 HydrophobicContact CE2-CD1 3.76Å
344L95.7Very high90.7Very high0 Ų015.6 Ų15.60%07%0.072CC..Hα-helixtrans-58.7-52173.2177.754.5000111W289 L340 R341 L342 Q346 G347 I348 L363 A366 E580 I583 I584W289-L344 HydrophobicContact CZ3-CD2 4.26Å; L340-L344 WeakPolarHBondContact O-CB 3.47Å; L340-L344 PolarHBondContact O-N 3.04Å; R341-L344 PolarHBondContact O-N 3.28Å; L342-L344 VanDerWaalsContact C-N 3.34Å; L342-L344 PolarHBondContact O-N 3.17Å; L344-Q346 PolarHBondContact O-N 3.2Å; L344-G347 PolarHBondContact O-N 3.22Å; L344-I348 HydrophobicContact CD1-CD1 3.85Å; L344-I348 HydrophobicContact CD1-CG1 4.25Å; L344-I348 HydrophobicContact CG-CD1 3.89Å; L344-I348 VanDerWaalsContact O-CG1 3.28Å; L344-I348 WeakPolarHBondContact O-CG1 3.31Å; L344-I348 PolarHBondContact O-N 2.94Å; L344-L363 HydrophobicContact CD1-CD2 3.92Å; L344-A366 HydrophobicContact CB-CB 4.23Å; L344-E580 HydrophobicContact CD2-CB 3.89Å; L344-E580 HydrophobicContact CD2-CG 3.66Å; L344-I583 HydrophobicContact CD1-CG2 3.98Å; L344-I583 HydrophobicContact CD2-CB 4.35Å; L344-I583 HydrophobicContact CD2-CG2 4.31Å; L344-I583 HydrophobicContact CG-CG2 4.44Å; L344-I584 HydrophobicContact CD1-CG1 3.58Å; L344-I584 HydrophobicContact CD2-CG1 4.21Å; L344-I584 HydrophobicContact CG-CG1 4.38Å
345L94.2Very high90.9Very high3 Ų317.4 Ų17.42%0.0168%0.082CC..Hα-helixtrans-65.5-38179.9-71.1173.9000112.6L285 V288 W289 F292 L307 R341 L342 I348 R349L285-L345 HydrophobicContact CD2-CD1 4.48Å; V288-L345 HydrophobicContact CB-CD1 4.18Å; V288-L345 HydrophobicContact CG1-CB 4.36Å; V288-L345 HydrophobicContact CG1-CD1 4.01Å; V288-L345 HydrophobicContact CG1-CD2 4.23Å; V288-L345 HydrophobicContact CG1-CG 4.44Å; W289-L345 HydrophobicContact CB-CD1 4.45Å; W289-L345 HydrophobicContact CE3-CD1 4.38Å; W289-L345 HydrophobicContact CE3-CD2 3.94Å; W289-L345 HydrophobicContact CE3-CG 4.32Å; F292-L345 HydrophobicContact CB-CD2 4.17Å; F292-L345 HydrophobicContact CG-CD2 4.45Å; L307-L345 HydrophobicContact CD1-CB 4.27Å; L307-L345 HydrophobicContact CD2-CB 3.75Å; L307-L345 HydrophobicContact CD2-CD1 4.24Å; R341-L345 HydrophobicContact CG-CD1 4.21Å; R341-L345 WeakPolarHBondContact O-CB 3.13Å; R341-L345 WeakPolarHBondContact O-CG 3.45Å; R341-L345 PolarHBondContact O-N 3.34Å; L342-L345 PolarHBondContact O-N 3.1Å; L345-I348 HydrophobicContact CD2-CD1 4.46Å; L345-I348 PolarHBondContact O-N 3.46Å; L345-R349 WeakPolarHBondContact O-CB 3.49Å; L345-R349 PolarHBondContact O-N 3.23Å
346Q93.4Very high90.9Very high7 Ų719.2 Ų19.23%0.0339%0.092CC..Hα-helixtrans-62.4-43.6172.3-74.7-179-33.700111.4L307 L342 Y343 L344 R349 N350 Y362L307-Q346 HydrophobicContact CB-CG 4.2Å; L307-Q346 HydrophobicContact CD1-CG 4.06Å; L342-Q346 HydrophobicContact CD1-CG 4.21Å; L342-Q346 WeakPolarHBondContact O-CB 3.47Å; L342-Q346 VanDerWaalsContact O-CG 3.32Å; L342-Q346 WeakPolarHBondContact O-CG 3.44Å; L342-Q346 PolarHBondContact O-N 3.13Å; Y343-Q346 PolarHBondContact O-N 3.12Å; L344-Q346 PolarHBondContact O-N 3.2Å; Q346-R349 PolarHBondContact O-N 3.37Å; Q346-N350 WeakPolarHBondContact O-CB 3.37Å; Q346-N350 PolarHBondContact O-N 3Å; Q346-N350 PolarHBondContact O-ND2 3.43Å; Q346-Y362 HydrophobicContact CB-CD1 4.24Å; Q346-Y362 HydrophobicContact CB-CD2 4.32Å; Q346-Y362 HydrophobicContact CB-CG 4.1Å; Q346-Y362 VanDerWaalsContact OE1-CE1 3.27Å
347G92.8Very high90.9Very high0 Ų021.7 Ų21.70%011%0.11CC..Hα-helixtrans-60.2-48.217600000112.5Y343 L344 N350 Y351Y343-G347 PolarHBondContact O-N 3.32Å; L344-G347 PolarHBondContact O-N 3.22Å; G347-N350 PolarHBondContact O-N 2.9Å; G347-Y351 WeakPolarHBondContact O-CB 3.44Å; G347-Y351 PolarHBondContact O-N 3.23Å
348I91.4Very high90.9Very high1 Ų125.4 Ų25.41%0.00513%0.127CC..Hα-helixtrans-58.9-51.2175.6-68162.5000110.4F292 L297 L344 L345 N350 Y351 H352 I583 Y587F292-I348 HydrophobicContact CD2-CD1 4.18Å; F292-I348 HydrophobicContact CD2-CG2 3.86Å; F292-I348 HydrophobicContact CE2-CD1 3.86Å; F292-I348 HydrophobicContact CE2-CG2 3.88Å; F292-I348 HydrophobicContact CZ-CD1 4.06Å; L297-I348 HydrophobicContact CD1-CG2 3.92Å; L344-I348 HydrophobicContact CD1-CD1 3.85Å; L344-I348 HydrophobicContact CD1-CG1 4.25Å; L344-I348 HydrophobicContact CG-CD1 3.89Å; L344-I348 VanDerWaalsContact O-CG1 3.28Å; L344-I348 WeakPolarHBondContact O-CG1 3.31Å; L344-I348 PolarHBondContact O-N 2.94Å; L345-I348 HydrophobicContact CD2-CD1 4.46Å; L345-I348 PolarHBondContact O-N 3.46Å; I348-N350 VanDerWaalsContact C-N 3.32Å; I348-N350 PolarHBondContact O-N 2.69Å; I348-Y351 WeakPolarHBondContact O-CB 3.48Å; I348-Y351 PolarHBondContact O-N 3.26Å; I348-Y351 VanDerWaalsContact O-N 3.17Å; I348-H352 PolarHBondContact O-CD2 3.49Å; I348-H352 PolarHBondContact O-N 3.17Å; I348-I583 HydrophobicContact CD1-CG2 3.64Å; I348-I583 HydrophobicContact CG1-CG2 4.44Å; I348-Y587 HydrophobicContact CB-CD1 4.44Å; I348-Y587 HydrophobicContact CB-CE1 4.18Å; I348-Y587 HydrophobicContact CD1-CE2 4.43Å; I348-Y587 HydrophobicContact CG1-CD1 3.95Å; I348-Y587 HydrophobicContact CG1-CD2 4.03Å; I348-Y587 HydrophobicContact CG1-CE1 3.98Å; I348-Y587 HydrophobicContact CG1-CE2 4.07Å; I348-Y587 HydrophobicContact CG1-CG 3.97Å; I348-Y587 HydrophobicContact CG2-CE1 3.8Å
349R89.8Confident90.9Very high55 Ų5524.8 Ų24.821%0.20812%0.124CC..Hα-helixtrans-58.7-43.4179.8176.4-94.9171.9-148.1-1.6112.1E304 L307 L345 Q346 Y351 H352 S353E304-R349 IonicContact OE1-CZ 2.74Å; E304-R349 IonicContact OE1-NH2 3.47Å; E304-R349 PolarHBondContact OE1-NH2 3.28Å; E304-R349 IonicContact OE2-CZ 3.83Å; E304-R349 IonicContact OE2-NE 3.5Å; E304-R349 IonicContact OE2-NH2 3.51Å; E304-R349 PolarHBondContact OE2-NH2 2.76Å; L307-R349 HydrophobicContact CD1-CB 4.33Å; L345-R349 WeakPolarHBondContact O-CB 3.49Å; L345-R349 PolarHBondContact O-N 3.23Å; Q346-R349 PolarHBondContact O-N 3.37Å; R349-Y351 VanDerWaalsContact C-N 3.34Å; R349-H352 PolarHBondContact O-N 3.49Å; R349-S353 WeakPolarHBondContact O-CB 3.48Å; R349-S353 PolarHBondContact O-N 2.93Å; R349-S353 PolarHBondContact O-OG 3.15Å
350N89.4Confident91Very high14 Ų1427.3 Ų27.38%0.07513%0.133CC..Hα-helixtrans-66.1-38.3178.5-76.5-39.7000111.5Q346 G347 I348 S353 G354 N355 E358 A359 Y362Q346-N350 WeakPolarHBondContact O-CB 3.37Å; Q346-N350 PolarHBondContact O-N 3Å; Q346-N350 PolarHBondContact O-ND2 3.43Å; G347-N350 PolarHBondContact O-N 2.9Å; I348-N350 VanDerWaalsContact C-N 3.32Å; I348-N350 PolarHBondContact O-N 2.69Å; N350-S353 CarbonylContact O-C 3.6Å; N350-S353 PolarHBondContact O-N 3.21Å; N350-G354 PolarHBondContact O-N 2.94Å; N350-G354 VanDerWaalsContact O-N 3.15Å; N350-N355 HydrophobicContact CB-CB 4.22Å; N350-N355 PolarHBondContact O-N 3.3Å; N350-E358 HydrophobicContact CB-CB 4.38Å; N350-A359 HydrophobicContact CB-CB 3.95Å; N350-Y362 WeakPolarHBondContact ND2-CD2 3.34Å
351Y89.1Confident91Very high1 Ų131.9 Ų31.90%0.00416%0.155CC..Hα-helixtrans-58.7-52.1172178.9-96000110.8A2 Y6 G347 I348 R349 S353 G354 Y587 Y590 V591A2-Y351 HydrophobicContact CB-CE1 4.13Å; Y6-Y351 HydrophobicContact CD2-CD2 4Å; Y6-Y351 HydrophobicContact CD2-CE1 4.38Å; Y6-Y351 AromaticContact CD2-CE2 3.77Å; Y6-Y351 HydrophobicContact CD2-CE2 3.77Å; Y6-Y351 HydrophobicContact CD2-CG 4.42Å; Y6-Y351 AromaticContact CD2-CZ 3.97Å; Y6-Y351 VanDerWaalsContact CD2-O 3.26Å; Y6-Y351 WeakPolarHBondContact CD2-O 3.44Å; Y6-Y351 HydrophobicContact CE2-CE2 4.33Å; Y6-Y351 HydrophobicContact CG-CE1 4.38Å; Y6-Y351 HydrophobicContact CG-CE2 4.22Å; Y6-Y351 AromaticContact CG-CZ 3.99Å; G347-Y351 WeakPolarHBondContact O-CB 3.44Å; G347-Y351 PolarHBondContact O-N 3.23Å; I348-Y351 WeakPolarHBondContact O-CB 3.48Å; I348-Y351 PolarHBondContact O-N 3.26Å; I348-Y351 VanDerWaalsContact O-N 3.17Å; R349-Y351 VanDerWaalsContact C-N 3.34Å; Y351-S353 PolarHBondContact O-N 3.15Å; Y351-S353 VanDerWaalsContact O-N 3.15Å; Y351-G354 PolarHBondContact O-N 3.48Å; Y351-Y587 AromaticContact CD1-CD1 3.95Å; Y351-Y587 HydrophobicContact CD1-CD1 3.95Å; Y351-Y587 AromaticContact CD1-CE1 3.74Å; Y351-Y587 HydrophobicContact CD1-CE1 3.74Å; Y351-Y587 HydrophobicContact CE1-CE1 4.35Å; Y351-Y587 HydrophobicContact CG-CD1 4.11Å; Y351-Y587 HydrophobicContact CG-CE1 4.32Å; Y351-Y590 HydrophobicContact CE1-CD2 4.38Å; Y351-V591 HydrophobicContact CD2-CG2 3.62Å; Y351-V591 HydrophobicContact CE2-CG2 4.05Å
352H85.3Confident91Very high30 Ų3032 Ų3214%0.13916%0.155CC..Hα-helixtrans-65.1-20.7178.4-71.7-81.3000113.8A9 L297 I348 R349 G354 Y587A9-H352 WeakPolarHBondContact CB-O 3.49Å; L297-H352 WeakPolarHBondContact CD1-CD2 3.16Å; L297-H352 WeakPolarHBondContact CD1-NE2 3.3Å; I348-H352 PolarHBondContact O-CD2 3.49Å; I348-H352 PolarHBondContact O-N 3.17Å; R349-H352 PolarHBondContact O-N 3.49Å; H352-G354 VanDerWaalsContact C-N 3.34Å; H352-Y587 AromaticContact NE2-CE1 3.58Å; H352-Y587 AromaticContact NE2-CZ 3.67Å; H352-Y587 PolarHBondContact NE2-OH 2.93Å
353S85.1Confident91.1Very high41 Ų4132 Ų3229%0.28716%0.155SC..THydrogen-bonded Turntrans-84-7.5174.6-56.80000113.3R349 N350 Y351R349-S353 WeakPolarHBondContact O-CB 3.48Å; R349-S353 PolarHBondContact O-N 2.93Å; R349-S353 PolarHBondContact O-OG 3.15Å; N350-S353 CarbonylContact O-C 3.6Å; N350-S353 PolarHBondContact O-N 3.21Å; Y351-S353 PolarHBondContact O-N 3.15Å; Y351-S353 VanDerWaalsContact O-N 3.15Å
354G84.4Confident91.1Very high0 Ų030.8 Ų30.80%015%0.152CC..THydrogen-bonded Turntrans82.715.4-176.100000114.4K10 N350 Y351 H352 D356K10-G354 VanDerWaalsContact CD-O 3.32Å; K10-G354 WeakPolarHBondContact CD-O 3.24Å; K10-G354 WeakPolarHBondContact CE-O 3.2Å; K10-G354 PolarHBondContact NZ-O 3Å; N350-G354 PolarHBondContact O-N 2.94Å; N350-G354 VanDerWaalsContact O-N 3.15Å; Y351-G354 PolarHBondContact O-N 3.48Å; H352-G354 VanDerWaalsContact C-N 3.34Å; G354-D356 PolarHBondContact O-N 3.32Å
355N87.2Confident91Very high47 Ų4734.8 Ų34.825%0.25117%0.169SC..  trans-96.282-179.8-69.1-1000111.4N350 V357 E358 A359N350-N355 HydrophobicContact CB-CB 4.22Å; N350-N355 PolarHBondContact O-N 3.3Å; N355-V357 PolarHBondContact O-N 3.33Å; N355-E358 HydrophobicContact CB-CB 4.4Å; N355-E358 WeakPolarHBondContact CB-OE2 3.35Å; N355-E358 VanDerWaalsContact CG-OE2 3.27Å; N355-E358 PolarHBondContact ND2-OE2 2.95Å; N355-A359 WeakPolarHBondContact O-CB 3.31Å; N355-A359 PolarHBondContact O-N 3.26Å
356D85.8Confident91.1Very high38 Ų3834.6 Ų34.620%0.20317%0.169CC..Hα-helixtrans-61.6-40.5-172.2-60.6-59.3000114.7Y6 K10 G354 Y360Y6-D356 WeakPolarHBondContact CE2-OD1 3.09Å; Y6-D356 PolarHBondContact OH-OD1 3.08Å; Y6-D356 VanDerWaalsContact OH-OD1 3.05Å; Y6-D356 PolarHBondContact OH-OD2 2.75Å; Y6-D356 VanDerWaalsContact OH-OD2 3.08Å; K10-D356 WeakPolarHBondContact CE-OD2 3.42Å; K10-D356 IonicContact NZ-OD2 3.36Å; K10-D356 PolarHBondContact NZ-OD2 2.75Å; G354-D356 PolarHBondContact O-N 3.32Å; D356-Y360 VanDerWaalsContact O-CB 3.3Å; D356-Y360 WeakPolarHBondContact O-CB 3.5Å; D356-Y360 PolarHBondContact O-N 3.02Å
357V89.8Confident91.3Very high95 Ų9538.1 Ų38.158%0.57618%0.181SC*.Hα-helixtrans-65.9-53.9-175.3179.70000109.3N355 A359 Y360 E361N355-V357 PolarHBondContact O-N 3.33Å; V357-A359 PolarHBondContact O-N 2.94Å; V357-Y360 WeakPolarHBondContact O-CB 3.47Å; V357-Y360 PolarHBondContact O-N 3.29Å; V357-E361 WeakPolarHBondContact O-CG 3.46Å; V357-E361 PolarHBondContact O-N 3.05Å
358E91.2Very high91.3Very high84 Ų8443.8 Ų43.839%0.39321%0.208SC..Hα-helixtrans-64.2-41.4178.5-67.6141.9-163.200111.3N350 N355 Y360 E361 Y362N350-E358 HydrophobicContact CB-CB 4.38Å; N355-E358 HydrophobicContact CB-CB 4.4Å; N355-E358 WeakPolarHBondContact CB-OE2 3.35Å; N355-E358 VanDerWaalsContact CG-OE2 3.27Å; N355-E358 PolarHBondContact ND2-OE2 2.95Å; E358-Y360 VanDerWaalsContact C-N 3.34Å; E358-Y360 PolarHBondContact O-N 2.75Å; E358-E361 PolarHBondContact O-N 2.56Å; E358-Y362 HydrophobicContact CB-CD2 4.44Å; E358-Y362 HydrophobicContact CB-CE2 4.45Å; E358-Y362 WeakPolarHBondContact O-CD2 3.28Å; E358-Y362 PolarHBondContact O-N 3.13Å
359A92.4Very high91.4Very high0 Ų044.8 Ų44.80%021%0.213CC..Hα-helixtrans-56.6-49.1174.900000111.2N350 N355 V357 E361 Y362 L363 V591N350-A359 HydrophobicContact CB-CB 3.95Å; N355-A359 WeakPolarHBondContact O-CB 3.31Å; N355-A359 PolarHBondContact O-N 3.26Å; V357-A359 PolarHBondContact O-N 2.94Å; A359-E361 PolarHBondContact O-N 3.34Å; A359-Y362 PolarHBondContact O-N 2.92Å; A359-L363 VanDerWaalsContact O-CB 3.31Å; A359-L363 WeakPolarHBondContact O-CB 3.48Å; A359-L363 WeakPolarHBondContact O-CD1 3.41Å; A359-L363 WeakPolarHBondContact O-CG 3.3Å; A359-L363 PolarHBondContact O-N 2.91Å; A359-V591 HydrophobicContact CB-CG2 4.48Å
360Y94.1Very high91.6Very high65 Ų6543.2 Ų43.226%0.25521%0.208SC..Hα-helixtrans-60.1-45.2177.1-173.5-105.1000112.3D356 V357 E358 N364 L588 V591 E592 K595D356-Y360 VanDerWaalsContact O-CB 3.3Å; D356-Y360 WeakPolarHBondContact O-CB 3.5Å; D356-Y360 PolarHBondContact O-N 3.02Å; V357-Y360 WeakPolarHBondContact O-CB 3.47Å; V357-Y360 PolarHBondContact O-N 3.29Å; E358-Y360 VanDerWaalsContact C-N 3.34Å; E358-Y360 PolarHBondContact O-N 2.75Å; Y360-N364 WeakPolarHBondContact CD1-ND2 3.39Å; Y360-N364 WeakPolarHBondContact CD2-ND2 3.41Å; Y360-N364 WeakPolarHBondContact CE1-ND2 3.34Å; Y360-N364 VanDerWaalsContact CE2-ND2 3.27Å; Y360-N364 WeakPolarHBondContact CE2-ND2 3.28Å; Y360-N364 WeakPolarHBondContact O-CB 3.33Å; Y360-N364 PolarHBondContact O-N 3.03Å; Y360-N364 PolarHBondContact O-ND2 3.15Å; Y360-L588 HydrophobicContact CD2-CD2 4.42Å; Y360-L588 HydrophobicContact CE2-CD2 4.49Å; Y360-V591 HydrophobicContact CD2-CG1 3.78Å; Y360-V591 HydrophobicContact CG-CG1 4.27Å; Y360-E592 HydrophobicContact CE2-CG 3.93Å; Y360-K595 HydrophobicContact CD2-CD 4.49Å
361E95.1Very high91.8Very high96 Ų9649.9 Ų49.945%0.44924%0.236SC..Hα-helixtrans-61.5-48.6-179.7-74.8177.8-173.500111.9V357 E358 A359 N364 K365V357-E361 WeakPolarHBondContact O-CG 3.46Å; V357-E361 PolarHBondContact O-N 3.05Å; E358-E361 PolarHBondContact O-N 2.56Å; A359-E361 PolarHBondContact O-N 3.34Å; E361-N364 PolarHBondContact O-N 3.42Å; E361-K365 WeakPolarHBondContact O-CG 3.36Å; E361-K365 PolarHBondContact O-N 2.89Å
362Y95.3Very high91.8Very high49 Ų4955.5 Ų55.519%0.19226%0.262CS..Hα-helixtrans-68.1-41180-76.2-64.4000112.5Y343 Q346 N350 E358 A359 N364 K365 A366Y343-Y362 AromaticContact CD1-CD1 3.81Å; Y343-Y362 HydrophobicContact CD1-CD1 3.81Å; Y343-Y362 HydrophobicContact CD1-CE1 4.12Å; Y343-Y362 HydrophobicContact CE1-CD1 4.49Å; Y343-Y362 HydrophobicContact CE1-CE1 4.43Å; Y343-Y362 HydrophobicContact CG-CD1 4.4Å; Q346-Y362 HydrophobicContact CB-CD1 4.24Å; Q346-Y362 HydrophobicContact CB-CD2 4.32Å; Q346-Y362 HydrophobicContact CB-CG 4.1Å; Q346-Y362 VanDerWaalsContact OE1-CE1 3.27Å; N350-Y362 WeakPolarHBondContact ND2-CD2 3.34Å; E358-Y362 HydrophobicContact CB-CD2 4.44Å; E358-Y362 HydrophobicContact CB-CE2 4.45Å; E358-Y362 WeakPolarHBondContact O-CD2 3.28Å; E358-Y362 PolarHBondContact O-N 3.13Å; A359-Y362 PolarHBondContact O-N 2.92Å; Y362-N364 VanDerWaalsContact C-N 3.28Å; Y362-N364 PolarHBondContact O-N 3.32Å; Y362-K365 HydrophobicContact CD1-CD 4.35Å; Y362-K365 PolarHBondContact O-N 3.25Å; Y362-A366 PolarHBondContact O-N 2.92Å
363L95.9Very high92.1Very high0 Ų054.4 Ų54.40%026%0.258CS..Hα-helixtrans-63.1-35.4174.8-69.5169.1000111.8L344 A359 A366 R367 L588 V591L344-L363 HydrophobicContact CD1-CD2 3.92Å; A359-L363 VanDerWaalsContact O-CB 3.31Å; A359-L363 WeakPolarHBondContact O-CB 3.48Å; A359-L363 WeakPolarHBondContact O-CD1 3.41Å; A359-L363 WeakPolarHBondContact O-CG 3.3Å; A359-L363 PolarHBondContact O-N 2.91Å; L363-A366 PolarHBondContact O-N 3.07Å; L363-R367 WeakPolarHBondContact O-CB 3.39Å; L363-R367 PolarHBondContact O-N 3.11Å; L363-L588 HydrophobicContact CB-CD2 3.55Å; L363-L588 HydrophobicContact CB-CG 4Å; L363-L588 HydrophobicContact CD1-CD2 4.28Å; L363-V591 HydrophobicContact CD1-CG2 4.07Å
364N95.3Very high92.4Very high20 Ų2058.6 Ų58.611%0.10727%0.268CS..Hα-helixtrans-69.6-40.1174.1-84.9-63000113.4Y360 E361 Y362 A366 R367 Q368Y360-N364 WeakPolarHBondContact CD1-ND2 3.39Å; Y360-N364 WeakPolarHBondContact CD2-ND2 3.41Å; Y360-N364 WeakPolarHBondContact CE1-ND2 3.34Å; Y360-N364 VanDerWaalsContact CE2-ND2 3.27Å; Y360-N364 WeakPolarHBondContact CE2-ND2 3.28Å; Y360-N364 WeakPolarHBondContact O-CB 3.33Å; Y360-N364 PolarHBondContact O-N 3.03Å; Y360-N364 PolarHBondContact O-ND2 3.15Å; E361-N364 PolarHBondContact O-N 3.42Å; Y362-N364 VanDerWaalsContact C-N 3.28Å; Y362-N364 PolarHBondContact O-N 3.32Å; N364-A366 VanDerWaalsContact C-N 3.3Å; N364-A366 PolarHBondContact O-N 3.15Å; N364-R367 PolarHBondContact O-N 2.97Å; N364-R367 VanDerWaalsContact OD1-CZ 3.23Å; N364-R367 PolarHBondContact OD1-NE 3.12Å; N364-R367 PolarHBondContact OD1-NH2 3.33Å; N364-Q368 WeakPolarHBondContact O-CG 3.44Å; N364-Q368 PolarHBondContact O-N 2.91Å
365K95.1Very high92.6Very high84 Ų8459.8 Ų59.837%0.36527%0.274SS..Hα-helixtrans-59.1-44.3172-72.5172.6-178.1171.10110.8Y343 E361 Y362 Q368 L369Y343-K365 HydrophobicContact CD2-CB 3.77Å; Y343-K365 HydrophobicContact CE2-CB 4.25Å; Y343-K365 HydrophobicContact CG-CB 4.18Å; E361-K365 WeakPolarHBondContact O-CG 3.36Å; E361-K365 PolarHBondContact O-N 2.89Å; Y362-K365 HydrophobicContact CD1-CD 4.35Å; Y362-K365 PolarHBondContact O-N 3.25Å; K365-Q368 PolarHBondContact O-N 2.61Å; K365-L369 PolarHBondContact O-N 3.3Å
366A95.9Very high92.8Very high0 Ų060.8 Ų60.80%028%0.28CS..Hα-helixtrans-60.9-44.4174.700000111.8L344 Y362 L363 N364 Q368 L369 F370 I584L344-A366 HydrophobicContact CB-CB 4.23Å; Y362-A366 PolarHBondContact O-N 2.92Å; L363-A366 PolarHBondContact O-N 3.07Å; N364-A366 VanDerWaalsContact C-N 3.3Å; N364-A366 PolarHBondContact O-N 3.15Å; A366-Q368 PolarHBondContact O-N 2.91Å; A366-L369 PolarHBondContact O-N 2.88Å; A366-F370 WeakPolarHBondContact O-CB 3.43Å; A366-F370 PolarHBondContact O-N 3.43Å; A366-I584 HydrophobicContact CB-CD1 4.04Å; A366-I584 HydrophobicContact CB-CG1 4.27Å
367R96.4Very high93.1Very high80 Ų8062.5 Ų62.530%0.30229%0.293SS..Hα-helixtrans-62.2-38.9175.9-177.1173.166176.83.6113.1L363 N364 F370 K371 I584 L588 E592L363-R367 WeakPolarHBondContact O-CB 3.39Å; L363-R367 PolarHBondContact O-N 3.11Å; N364-R367 PolarHBondContact O-N 2.97Å; N364-R367 VanDerWaalsContact OD1-CZ 3.23Å; N364-R367 PolarHBondContact OD1-NE 3.12Å; N364-R367 PolarHBondContact OD1-NH2 3.33Å; R367-F370 PolarHBondContact O-N 3.22Å; R367-K371 WeakPolarHBondContact O-CG 3.48Å; R367-K371 PolarHBondContact O-N 3.31Å; R367-I584 HydrophobicContact CB-CG2 3.92Å; R367-I584 HydrophobicContact CG-CG2 4.41Å; R367-L588 HydrophobicContact CB-CD1 4.22Å; R367-L588 HydrophobicContact CG-CD1 4.42Å; R367-E592 IonicContact NH1-OE1 3.57Å
368Q94.5Very high93.4Very high120 Ų12060.6 Ų60.656%0.56128%0.284SS*.Hα-helixtrans-65.6-49.1176.5-75172.3-1000110.7N364 K365 A366 F370 K371 E372N364-Q368 WeakPolarHBondContact O-CG 3.44Å; N364-Q368 PolarHBondContact O-N 2.91Å; K365-Q368 PolarHBondContact O-N 2.61Å; A366-Q368 PolarHBondContact O-N 2.91Å; Q368-F370 VanDerWaalsContact C-N 3.28Å; Q368-F370 PolarHBondContact O-N 3.03Å; Q368-K371 PolarHBondContact O-N 2.87Å; Q368-K371 VanDerWaalsContact O-N 3.16Å; Q368-E372 PolarHBondContact O-N 3.18Å; Q368-E372 VanDerWaalsContact O-N 3.15Å
369L92.9Very high93.5Very high22 Ų2260 Ų6012%0.11528%0.28CS..Hα-helixtrans-60.4-37.7174.9-73.2-179.6000112.2K336 F339 L340 Y343 K365 A366 K371 E372 L373K336-L369 HydrophobicContact CD-CD2 4.4Å; F339-L369 HydrophobicContact CB-CD1 3.88Å; L340-L369 HydrophobicContact CB-CB 4.09Å; L340-L369 HydrophobicContact CB-CD1 4.22Å; L340-L369 HydrophobicContact CD1-CB 4.26Å; L340-L369 HydrophobicContact CG-CB 4.31Å; Y343-L369 HydrophobicContact CD2-CD1 3.7Å; Y343-L369 HydrophobicContact CE2-CD1 3.76Å; K365-L369 PolarHBondContact O-N 3.3Å; A366-L369 PolarHBondContact O-N 2.88Å; L369-K371 VanDerWaalsContact C-N 3.33Å; L369-K371 PolarHBondContact O-N 3.34Å; L369-E372 PolarHBondContact O-N 2.89Å; L369-L373 HydrophobicContact CB-CD1 4.39Å; L369-L373 WeakPolarHBondContact O-CB 3.34Å; L369-L373 VanDerWaalsContact O-CG 3.22Å; L369-L373 WeakPolarHBondContact O-CG 3.1Å; L369-L373 PolarHBondContact O-N 3Å
370F94.1Very high93.6Very high22 Ų2260.8 Ų60.810%0.09629%0.285CS..Hα-helixtrans-58.5-46175.7175.9-98000111.4L340 A366 R367 Q368 E372 L373 Y374 L577 E581 I584L340-F370 VanDerWaalsContact CD1-CA 3.49Å; L340-F370 HydrophobicContact CD1-CB 3.85Å; L340-F370 HydrophobicContact CD1-CD2 4.39Å; A366-F370 WeakPolarHBondContact O-CB 3.43Å; A366-F370 PolarHBondContact O-N 3.43Å; R367-F370 PolarHBondContact O-N 3.22Å; Q368-F370 VanDerWaalsContact C-N 3.28Å; Q368-F370 PolarHBondContact O-N 3.03Å; F370-E372 VanDerWaalsContact C-N 3.29Å; F370-E372 PolarHBondContact O-N 3.04Å; F370-L373 PolarHBondContact O-N 3.1Å; F370-Y374 HydrophobicContact CE1-CD2 4.4Å; F370-Y374 AromaticContact CZ-CD2 3.9Å; F370-Y374 HydrophobicContact CZ-CD2 3.9Å; F370-Y374 WeakPolarHBondContact O-CB 3.44Å; F370-Y374 PolarHBondContact O-N 2.86Å; F370-L577 HydrophobicContact CD2-CB 4.04Å; F370-L577 HydrophobicContact CD2-CD1 4.32Å; F370-L577 HydrophobicContact CE2-CB 3.81Å; F370-E581 HydrophobicContact CD2-CB 4.47Å; F370-E581 HydrophobicContact CE1-CB 4.33Å; F370-E581 HydrophobicContact CE1-CG 3.92Å; F370-E581 HydrophobicContact CE2-CB 3.66Å; F370-E581 HydrophobicContact CE2-CG 4.16Å; F370-E581 HydrophobicContact CZ-CB 3.58Å; F370-E581 VanDerWaalsContact CZ-CD 3.45Å; F370-E581 HydrophobicContact CZ-CG 3.55Å; F370-I584 HydrophobicContact CB-CD1 4.22Å
371K92.3Very high93.6Very high154 Ų15461.8 Ų61.867%0.6730%0.295SS*.Hα-helixtrans-62.8-35.1177.2-69.6177.3179.6-171.60113R367 Q368 L369R367-K371 WeakPolarHBondContact O-CG 3.48Å; R367-K371 PolarHBondContact O-N 3.31Å; Q368-K371 PolarHBondContact O-N 2.87Å; Q368-K371 VanDerWaalsContact O-N 3.16Å; L369-K371 VanDerWaalsContact C-N 3.33Å; L369-K371 PolarHBondContact O-N 3.34Å
372E90.1Very high93.6Very high118 Ų11860.8 Ų60.855%0.55129%0.292SS*.Hα-helixtrans-70.9-38.2175.5-69.1178.2-157.500112.4K336 Q368 L369 F370K336-E372 IonicContact NZ-OE2 2.87Å; K336-E372 PolarHBondContact NZ-OE2 2.9Å; Q368-E372 PolarHBondContact O-N 3.18Å; Q368-E372 VanDerWaalsContact O-N 3.15Å; L369-E372 PolarHBondContact O-N 2.89Å; F370-E372 VanDerWaalsContact C-N 3.29Å; F370-E372 PolarHBondContact O-N 3.04Å
373L91.1Very high93.7Very high8 Ų858.4 Ų58.44%0.04228%0.283CS..Hα-helixtrans-93.9-10.5-171.7-65.4170.7000114.4G333 K336 V337 L340 L369 F370 I375 L577G333-L373 WeakPolarHBondContact O-CD2 3.33Å; K336-L373 HydrophobicContact CB-CD1 3.91Å; K336-L373 HydrophobicContact CB-CD2 3.82Å; K336-L373 HydrophobicContact CB-CG 4.32Å; K336-L373 HydrophobicContact CD-CD2 4.33Å; V337-L373 HydrophobicContact CG2-CD1 4.03Å; V337-L373 HydrophobicContact CG2-CD2 4.48Å; L340-L373 HydrophobicContact CB-CD1 4.27Å; L340-L373 HydrophobicContact CD1-CD1 3.94Å; L369-L373 HydrophobicContact CB-CD1 4.39Å; L369-L373 WeakPolarHBondContact O-CB 3.34Å; L369-L373 VanDerWaalsContact O-CG 3.22Å; L369-L373 WeakPolarHBondContact O-CG 3.1Å; L369-L373 PolarHBondContact O-N 3Å; F370-L373 PolarHBondContact O-N 3.1Å; L373-I375 WeakPolarHBondContact O-CG1 3.45Å; L373-I375 PolarHBondContact O-N 3.41Å; L373-L577 HydrophobicContact CB-CD1 3.75Å
374Y91.1Very high93.6Very high128 Ų12861.7 Ų61.750%0.50230%0.3SS..  trans-60.7129.9176.9179-96.3000110.1F370F370-Y374 HydrophobicContact CE1-CD2 4.4Å; F370-Y374 AromaticContact CZ-CD2 3.9Å; F370-Y374 HydrophobicContact CZ-CD2 3.9Å; F370-Y374 WeakPolarHBondContact O-CB 3.44Å; F370-Y374 PolarHBondContact O-N 2.86Å
375I89.9Confident93.6Very high26 Ų2668.2 Ų68.213%0.13333%0.33CS..  trans-113.2127.9-179.8-49177.7000107.9L373 P377 V380 R394 L397 R398L373-I375 WeakPolarHBondContact O-CG1 3.45Å; L373-I375 PolarHBondContact O-N 3.41Å; I375-P377 WeakPolarHBondContact O-CD 3.33Å; I375-V380 HydrophobicContact CG2-CG2 3.7Å; I375-R394 HydrophobicContact CD1-CB 3.78Å; I375-R394 HydrophobicContact CD1-CG 4.01Å; I375-R394 WeakPolarHBondContact CD1-O 3.44Å; I375-L397 HydrophobicContact CD1-CB 4.3Å; I375-L397 HydrophobicContact CG2-CB 4.02Å; I375-L397 HydrophobicContact CG2-CD1 3.5Å; I375-L397 HydrophobicContact CG2-CG 4.37Å; I375-R398 HydrophobicContact CD1-CG 3.74Å; I375-R398 HydrophobicContact CG1-CG 4.21Å
376D90.6Very high93.6Very high67 Ų6769.6 Ų69.636%0.35834%0.341SS..  trans-65.4122.4172.9-176.2-19.1000110.5S378 K379 V380D376-S378 PolarHBondContact O-N 3.4Å; D376-S378 WeakPolarHBondContact OD1-CB 3.39Å; D376-S378 PolarHBondContact OD1-N 2.62Å; D376-S378 PolarHBondContact OD1-OG 3.06Å; D376-S378 PolarHBondContact OD2-OG 3.33Å; D376-S378 VanDerWaalsContact OD2-OG 3.07Å; D376-K379 HydrophobicContact CB-CB 4.49Å; D376-K379 HydrophobicContact CB-CD 4.1Å; D376-K379 HydrophobicContact CB-CG 4.04Å; D376-K379 WeakPolarHBondContact O-CB 3.29Å; D376-K379 PolarHBondContact O-N 3.5Å; D376-V380 PolarHBondContact O-N 3.15Å
377P92.7Very high93.5Very high74 Ų7472.1 Ų72.148%0.48137%0.367SS..Hα-helixtrans-53.8-35.2177.7-26.835.2000113.6I375 K379 V380 D381I375-P377 WeakPolarHBondContact O-CD 3.33Å; P377-K379 VanDerWaalsContact C-N 3.25Å; P377-K379 PolarHBondContact O-N 3.47Å; P377-V380 WeakPolarHBondContact O-CB 3.41Å; P377-V380 PolarHBondContact O-N 2.98Å; P377-D381 PolarHBondContact O-N 2.9Å
378S94.4Very high93.4Very high56 Ų5669.3 Ų69.339%0.39236%0.357SS..Hα-helixtrans-63.3-32.4179.6670000112.7D376 D381 N382D376-S378 PolarHBondContact O-N 3.4Å; D376-S378 WeakPolarHBondContact OD1-CB 3.39Å; D376-S378 PolarHBondContact OD1-N 2.62Å; D376-S378 PolarHBondContact OD1-OG 3.06Å; D376-S378 PolarHBondContact OD2-OG 3.33Å; D376-S378 VanDerWaalsContact OD2-OG 3.07Å; S378-D381 PolarHBondContact O-N 2.85Å; S378-N382 VanDerWaalsContact O-CG 3.31Å; S378-N382 PolarHBondContact O-N 2.89Å; S378-N382 VanDerWaalsContact O-N 3.12Å; S378-N382 PolarHBondContact O-ND2 3.27Å
379K94.3Very high93.3Very high72 Ų7266.9 Ų66.931%0.31335%0.35SS..Hα-helixtrans-72.9-32.5175.6-64.6-176.9179.5-175.40112D376 P377 L383 L397 G402 V404D376-K379 HydrophobicContact CB-CB 4.49Å; D376-K379 HydrophobicContact CB-CD 4.1Å; D376-K379 HydrophobicContact CB-CG 4.04Å; D376-K379 WeakPolarHBondContact O-CB 3.29Å; D376-K379 PolarHBondContact O-N 3.5Å; P377-K379 VanDerWaalsContact C-N 3.25Å; P377-K379 PolarHBondContact O-N 3.47Å; K379-L383 PolarHBondContact O-N 2.88Å; K379-L397 HydrophobicContact CB-CD1 3.98Å; K379-L397 HydrophobicContact CB-CD2 4.35Å; K379-G402 WeakPolarHBondContact CD-O 3.36Å; K379-G402 PolarHBondContact NZ-O 3.25Å; K379-V404 HydrophobicContact CB-CG2 3.91Å; K379-V404 HydrophobicContact CD-CG2 4.25Å; K379-V404 HydrophobicContact CG-CG2 3.96Å
380V94.4Very high93.2Very high16 Ų1667.5 Ų67.510%0.09736%0.359CS..Hα-helixtrans-66.8-43.9173.2-178.30000109.5I375 D376 P377 N382 L383 L384 A393 R394 L397I375-V380 HydrophobicContact CG2-CG2 3.7Å; D376-V380 PolarHBondContact O-N 3.15Å; P377-V380 WeakPolarHBondContact O-CB 3.41Å; P377-V380 PolarHBondContact O-N 2.98Å; V380-N382 VanDerWaalsContact C-N 3.32Å; V380-N382 PolarHBondContact O-N 2.95Å; V380-L383 PolarHBondContact O-N 3.29Å; V380-L383 VanDerWaalsContact O-N 3.12Å; V380-L384 HydrophobicContact CG1-CD1 3.92Å; V380-L384 HydrophobicContact CG1-CG 4.45Å; V380-L384 WeakPolarHBondContact O-CG 3.45Å; V380-L384 PolarHBondContact O-N 3.47Å; V380-A393 HydrophobicContact CG1-CB 3.91Å; V380-R394 HydrophobicContact CG2-CG 4.18Å; V380-L397 HydrophobicContact CG2-CD1 3.88Å
381D95Very high93.1Very high86 Ų8668.2 Ų68.246%0.4636%0.362SS..Hα-helixtrans-59.5-39.9176.9-68.6-23.2000112.4P377 S378 L383 L384 Q385P377-D381 PolarHBondContact O-N 2.9Å; S378-D381 PolarHBondContact O-N 2.85Å; D381-L383 VanDerWaalsContact C-N 3.34Å; D381-L383 PolarHBondContact O-N 2.97Å; D381-L384 WeakPolarHBondContact O-CB 3.46Å; D381-L384 PolarHBondContact O-N 3.31Å; D381-Q385 WeakPolarHBondContact O-CG 3.26Å; D381-Q385 PolarHBondContact O-N 3.46Å
382N95.2Very high93.1Very high74 Ų7462.2 Ų62.240%0.39634%0.337SS..Hα-helixtrans-59.9-42.4174.5-68.9-20.5000112.3S378 V380 Q385 L386 V404S378-N382 VanDerWaalsContact O-CG 3.31Å; S378-N382 PolarHBondContact O-N 2.89Å; S378-N382 VanDerWaalsContact O-N 3.12Å; S378-N382 PolarHBondContact O-ND2 3.27Å; V380-N382 VanDerWaalsContact C-N 3.32Å; V380-N382 PolarHBondContact O-N 2.95Å; N382-Q385 PolarHBondContact O-N 3.09Å; N382-L386 PolarHBondContact O-N 3.01Å; N382-V404 HydrophobicContact CB-CG1 4.22Å
383L95.6Very high93.3Very high0 Ų056.6 Ų56.60%031%0.31CS..Hα-helixtrans-72.7-33.5177.6-68.7179.2000112.3K379 V380 D381 Q385 L386 G387 F388 A393 L397 V404 A407 A408 I411K379-L383 PolarHBondContact O-N 2.88Å; V380-L383 PolarHBondContact O-N 3.29Å; V380-L383 VanDerWaalsContact O-N 3.12Å; D381-L383 VanDerWaalsContact C-N 3.34Å; D381-L383 PolarHBondContact O-N 2.97Å; L383-Q385 VanDerWaalsContact C-N 3.32Å; L383-Q385 PolarHBondContact O-N 2.92Å; L383-L386 HydrophobicContact CD2-CD1 4.1Å; L383-L386 WeakPolarHBondContact O-CB 3Å; L383-L386 PolarHBondContact O-N 3.46Å; L383-L386 VanDerWaalsContact O-N 3.15Å; L383-G387 PolarHBondContact O-N 3.48Å; L383-F388 HydrophobicContact CB-CD2 4.13Å; L383-F388 HydrophobicContact CD2-CD2 4.08Å; L383-F388 HydrophobicContact CD2-CE2 4.29Å; L383-F388 WeakPolarHBondContact O-CB 3.15Å; L383-F388 WeakPolarHBondContact O-CD2 3.4Å; L383-F388 PolarHBondContact O-N 2.88Å; L383-A393 HydrophobicContact CB-CB 3.69Å; L383-A393 HydrophobicContact CD1-CB 3.82Å; L383-A393 HydrophobicContact CG-CB 4.4Å; L383-L397 HydrophobicContact CD1-CD1 3.87Å; L383-L397 HydrophobicContact CD1-CD2 4.02Å; L383-L397 HydrophobicContact CD1-CG 3.66Å; L383-V404 HydrophobicContact CD2-CG1 3.8Å; L383-V404 HydrophobicContact CG-CG1 4.15Å; L383-A407 HydrophobicContact CD1-CB 3.98Å; L383-A408 HydrophobicContact CD2-CB 3.87Å; L383-I411 HydrophobicContact CD1-CD1 4.17Å
384L95.4Very high93.3Very high69 Ų6958.9 Ų58.936%0.36132%0.318SS..Hα-helixtrans-60.7-41.3171.9-77.3159.2000111.3V380 D381 L386 G387 F388 A390V380-L384 HydrophobicContact CG1-CD1 3.92Å; V380-L384 HydrophobicContact CG1-CG 4.45Å; V380-L384 WeakPolarHBondContact O-CG 3.45Å; V380-L384 PolarHBondContact O-N 3.47Å; D381-L384 WeakPolarHBondContact O-CB 3.46Å; D381-L384 PolarHBondContact O-N 3.31Å; L384-L386 PolarHBondContact O-N 2.88Å; L384-G387 PolarHBondContact O-N 3.23Å; L384-F388 WeakPolarHBondContact CD2-O 3.29Å; L384-A390 HydrophobicContact CD2-CB 4.2Å
385Q95.4Very high93.4Very high157 Ų15752.9 Ų52.973%0.73430%0.295SS*.Hα-helixtrans-62.6-26.9175.3-71.4173.810.900113.1D381 N382 L383 G387D381-Q385 WeakPolarHBondContact O-CG 3.26Å; D381-Q385 PolarHBondContact O-N 3.46Å; N382-Q385 PolarHBondContact O-N 3.09Å; L383-Q385 VanDerWaalsContact C-N 3.32Å; L383-Q385 PolarHBondContact O-N 2.92Å; Q385-G387 PolarHBondContact O-N 3.5Å
386L93.4Very high93.5Very high113 Ų11351.7 Ų51.759%0.59229%0.289SS*.THydrogen-bonded Turntrans-79.5-1.9172.9-61.3176.5000113.3N382 L383 L384 F388 A408N382-L386 PolarHBondContact O-N 3.01Å; L383-L386 HydrophobicContact CD2-CD1 4.1Å; L383-L386 WeakPolarHBondContact O-CB 3Å; L383-L386 PolarHBondContact O-N 3.46Å; L383-L386 VanDerWaalsContact O-N 3.15Å; L384-L386 PolarHBondContact O-N 2.88Å; L386-F388 HydrophobicContact CB-CD2 3.92Å; L386-F388 HydrophobicContact CB-CE2 3.86Å; L386-F388 HydrophobicContact CD1-CE2 4.17Å; L386-A408 HydrophobicContact CD1-CB 4.13Å
387G93.8Very high93.6Very high53 Ų5348.6 Ų48.655%0.54627%0.272SS..THydrogen-bonded Turntrans89.216.1178.300000114.7L383 L384 Q385L383-G387 PolarHBondContact O-N 3.48Å; L384-G387 PolarHBondContact O-N 3.23Å; Q385-G387 PolarHBondContact O-N 3.5Å
388F94.1Very high93.5Very high20 Ų2045.7 Ų45.79%0.08825%0.252CS..  trans-83.4152.5170.3-59-60.1000111.2L383 L384 L386 A408 I411L383-F388 HydrophobicContact CB-CD2 4.13Å; L383-F388 HydrophobicContact CD2-CD2 4.08Å; L383-F388 HydrophobicContact CD2-CE2 4.29Å; L383-F388 WeakPolarHBondContact O-CB 3.15Å; L383-F388 WeakPolarHBondContact O-CD2 3.4Å; L383-F388 PolarHBondContact O-N 2.88Å; L384-F388 WeakPolarHBondContact CD2-O 3.29Å; L386-F388 HydrophobicContact CB-CD2 3.92Å; L386-F388 HydrophobicContact CB-CE2 3.86Å; L386-F388 HydrophobicContact CD1-CE2 4.17Å; F388-A408 HydrophobicContact CE2-CB 3.95Å; F388-A408 HydrophobicContact CZ-CB 4.48Å; F388-I411 HydrophobicContact CD1-CB 4.23Å; F388-I411 HydrophobicContact CD1-CG2 3.38Å; F388-I411 HydrophobicContact CD2-CD1 4.34Å; F388-I411 HydrophobicContact CE1-CB 4.04Å; F388-I411 HydrophobicContact CE1-CG2 3.48Å; F388-I411 VanDerWaalsContact CE1-CG2 3.48Å; F388-I411 HydrophobicContact CG-CD1 4.27Å; F388-I411 HydrophobicContact CG-CG2 4.12Å; F388-I411 HydrophobicContact CZ-CB 4.38Å; F388-I411 HydrophobicContact CZ-CG2 4.29Å
389T92.8Very high93.2Very high70 Ų7043.7 Ų43.743%0.42924%0.239SC..  trans-73.5157.5172.463.60000110.7Q391 E392 A393T389-Q391 PolarHBondContact O-N 2.89Å; T389-E392 WeakPolarHBondContact CB-OE2 3.23Å; T389-E392 WeakPolarHBondContact CG2-OE2 3.48Å; T389-E392 PolarHBondContact N-OE2 3.43Å; T389-E392 PolarHBondContact O-N 3.15Å; T389-E392 WeakPolarHBondContact OG1-CB 3.46Å; T389-E392 VanDerWaalsContact OG1-CD 3.28Å; T389-E392 WeakPolarHBondContact OG1-CG 3.33Å; T389-E392 PolarHBondContact OG1-N 3.34Å; T389-E392 PolarHBondContact OG1-OE2 2.95Å; T389-A393 WeakPolarHBondContact O-CB 3.48Å; T389-A393 PolarHBondContact O-N 3.36Å
390A92.3Very high93.1Very high35 Ų3541.3 Ų41.329%0.28923%0.231SC..Hα-helixtrans-59.2-35.4177.400000112.3L384 R394L384-A390 HydrophobicContact CD2-CB 4.2Å; A390-R394 WeakPolarHBondContact O-CG 3.32Å; A390-R394 PolarHBondContact O-N 3.45Å
391Q90.8Very high92.7Very high36 Ų3647.7 Ų47.717%0.16826%0.264CS..Hα-helixtrans-64.1-52.1175.2170.8167.579.200111.7T389 A393 R394 L395 D571 D574T389-Q391 PolarHBondContact O-N 2.89Å; Q391-A393 VanDerWaalsContact C-N 3.27Å; Q391-A393 PolarHBondContact O-N 3.11Å; Q391-R394 PolarHBondContact O-N 3.09Å; Q391-L395 HydrophobicContact CG-CD1 3.94Å; Q391-L395 HydrophobicContact CG-CG 4.47Å; Q391-L395 WeakPolarHBondContact O-CB 3.25Å; Q391-L395 WeakPolarHBondContact O-CG 3.17Å; Q391-L395 PolarHBondContact O-N 2.93Å; Q391-D571 PolarHBondContact NE2-OD1 3.14Å; Q391-D574 VanDerWaalsContact CB-OD2 3.3Å; Q391-D574 WeakPolarHBondContact CB-OD2 3.11Å; Q391-D574 HydrophobicContact CG-CB 4.07Å; Q391-D574 WeakPolarHBondContact CG-OD2 3.34Å; Q391-D574 PolarHBondContact NE2-OD2 3.46Å
392E92.1Very high92.3Very high29 Ų2944.5 Ų44.514%0.13625%0.252CS..Hα-helixtrans-60.5-40.5178.5-72.1166.1130.200111.4T389 G396 I411 R415T389-E392 WeakPolarHBondContact CB-OE2 3.23Å; T389-E392 WeakPolarHBondContact CG2-OE2 3.48Å; T389-E392 PolarHBondContact N-OE2 3.43Å; T389-E392 PolarHBondContact O-N 3.15Å; T389-E392 WeakPolarHBondContact OG1-CB 3.46Å; T389-E392 VanDerWaalsContact OG1-CD 3.28Å; T389-E392 WeakPolarHBondContact OG1-CG 3.33Å; T389-E392 PolarHBondContact OG1-N 3.34Å; T389-E392 PolarHBondContact OG1-OE2 2.95Å; E392-G396 WeakPolarHBondContact O-CA 3.11Å; E392-G396 PolarHBondContact O-N 3.4Å; E392-I411 HydrophobicContact CB-CD1 4.4Å; E392-I411 HydrophobicContact CB-CG2 4.04Å; E392-I411 HydrophobicContact CG-CG2 4.4Å; E392-I411 VanDerWaalsContact O-CD1 3.31Å; E392-I411 WeakPolarHBondContact O-CD1 3.21Å; E392-R415 VanDerWaalsContact CD-NH2 3.27Å; E392-R415 IonicContact OE1-CZ 2.64Å; E392-R415 IonicContact OE1-NE 2.64Å; E392-R415 PolarHBondContact OE1-NE 3.29Å; E392-R415 IonicContact OE1-NH2 2.88Å; E392-R415 PolarHBondContact OE1-NH2 2.73Å; E392-R415 VanDerWaalsContact OE1-NH2 3.1Å; E392-R415 IonicContact OE2-CZ 2.74Å; E392-R415 IonicContact OE2-NE 2.73Å; E392-R415 IonicContact OE2-NH2 3.69Å; E392-R415 PolarHBondContact OE2-NH2 2.96Å
393A94Very high92.2Very high0 Ų043.9 Ų43.90%025%0.249CC..Hα-helixtrans-60.1-49.4176.200000111.4V380 L383 T389 Q391 L397V380-A393 HydrophobicContact CG1-CB 3.91Å; L383-A393 HydrophobicContact CB-CB 3.69Å; L383-A393 HydrophobicContact CD1-CB 3.82Å; L383-A393 HydrophobicContact CG-CB 4.4Å; T389-A393 WeakPolarHBondContact O-CB 3.48Å; T389-A393 PolarHBondContact O-N 3.36Å; Q391-A393 VanDerWaalsContact C-N 3.27Å; Q391-A393 PolarHBondContact O-N 3.11Å; A393-L397 VanDerWaalsContact O-CB 3.28Å; A393-L397 WeakPolarHBondContact O-CB 3.48Å; A393-L397 WeakPolarHBondContact O-CD1 3.41Å; A393-L397 WeakPolarHBondContact O-CG 3.29Å; A393-L397 PolarHBondContact O-N 3.02Å
394R93Very high92.1Very high56 Ų5645.4 Ų45.421%0.21126%0.258CS..Hα-helixtrans-63.5-46.8178.3-73.4-172-62.7-93.9-1112.4I375 V380 A390 Q391 L397 R398 D574I375-R394 HydrophobicContact CD1-CB 3.78Å; I375-R394 HydrophobicContact CD1-CG 4.01Å; I375-R394 WeakPolarHBondContact CD1-O 3.44Å; V380-R394 HydrophobicContact CG2-CG 4.18Å; A390-R394 WeakPolarHBondContact O-CG 3.32Å; A390-R394 PolarHBondContact O-N 3.45Å; Q391-R394 PolarHBondContact O-N 3.09Å; R394-L397 PolarHBondContact O-N 3.07Å; R394-R398 WeakPolarHBondContact O-CG 3.42Å; R394-R398 PolarHBondContact O-N 3.1Å; R394-D574 IonicContact CZ-OD1 3.51Å; R394-D574 IonicContact CZ-OD2 2.71Å; R394-D574 IonicContact NE-OD1 3.17Å; R394-D574 PolarHBondContact NE-OD1 3.23Å; R394-D574 IonicContact NE-OD2 2.67Å; R394-D574 VanDerWaalsContact NH2-CG 3.32Å; R394-D574 IonicContact NH2-OD1 3.83Å; R394-D574 PolarHBondContact NH2-OD1 3.4Å; R394-D574 VanDerWaalsContact NH2-OD1 3.16Å; R394-D574 IonicContact NH2-OD2 3.64Å; R394-D574 PolarHBondContact NH2-OD2 3.12Å
395L91.5Very high92Very high2 Ų247.9 Ų47.91%0.0127%0.271CS..Hα-helixtrans-66.1-42.4179.7-68.4179.9000111.6K334 Q391 R398 A399 E570 L573 D574K334-L395 HydrophobicContact CD-CB 4.25Å; K334-L395 HydrophobicContact CD-CD2 4.37Å; K334-L395 WeakPolarHBondContact CE-O 3.45Å; K334-L395 HydrophobicContact CG-CD2 4.36Å; K334-L395 WeakPolarHBondContact CG-O 3.4Å; Q391-L395 HydrophobicContact CG-CD1 3.94Å; Q391-L395 HydrophobicContact CG-CG 4.47Å; Q391-L395 WeakPolarHBondContact O-CB 3.25Å; Q391-L395 WeakPolarHBondContact O-CG 3.17Å; Q391-L395 PolarHBondContact O-N 2.93Å; L395-R398 PolarHBondContact O-N 3.17Å; L395-A399 PolarHBondContact O-N 2.96Å; L395-E570 HydrophobicContact CD1-CB 4.02Å; L395-L573 HydrophobicContact CD2-CB 3.99Å; L395-D574 HydrophobicContact CD2-CB 4.33Å; L395-D574 HydrophobicContact CG-CB 4.43Å
396G92.1Very high91.9Very high1 Ų146 Ų461%0.0126%0.263CS..Hα-helixtrans-62.8-45.7176.600000112.1E392 R398 A399 C400E392-G396 WeakPolarHBondContact O-CA 3.11Å; E392-G396 PolarHBondContact O-N 3.4Å; G396-R398 VanDerWaalsContact C-N 3.33Å; G396-R398 PolarHBondContact O-N 3.35Å; G396-A399 PolarHBondContact O-N 3.15Å; G396-C400 PolarHBondContact O-N 3.38Å
397L92.6Very high91.9Very high1 Ų140.7 Ų40.71%0.00523%0.234CC..Hα-helixtrans-62.3-38.6176.4-72.8167000112I375 K379 V380 L383 A393 R394 C400 D401 G402 V404 A407I375-L397 HydrophobicContact CD1-CB 4.3Å; I375-L397 HydrophobicContact CG2-CB 4.02Å; I375-L397 HydrophobicContact CG2-CD1 3.5Å; I375-L397 HydrophobicContact CG2-CG 4.37Å; K379-L397 HydrophobicContact CB-CD1 3.98Å; K379-L397 HydrophobicContact CB-CD2 4.35Å; V380-L397 HydrophobicContact CG2-CD1 3.88Å; L383-L397 HydrophobicContact CD1-CD1 3.87Å; L383-L397 HydrophobicContact CD1-CD2 4.02Å; L383-L397 HydrophobicContact CD1-CG 3.66Å; A393-L397 VanDerWaalsContact O-CB 3.28Å; A393-L397 WeakPolarHBondContact O-CB 3.48Å; A393-L397 WeakPolarHBondContact O-CD1 3.41Å; A393-L397 WeakPolarHBondContact O-CG 3.29Å; A393-L397 PolarHBondContact O-N 3.02Å; R394-L397 PolarHBondContact O-N 3.07Å; L397-C400 CarbonylContact O-C 3.01Å; L397-C400 PolarHBondContact O-N 3.26Å; L397-D401 PolarHBondContact O-N 2.92Å; L397-G402 PolarHBondContact O-N 2.95Å; L397-V404 HydrophobicContact CD2-CG2 4.25Å; L397-A407 HydrophobicContact CD2-CB 3.92Å; L397-A407 HydrophobicContact CG-CB 4.22Å
398R91.2Very high92Very high13 Ų1338.9 Ų38.95%0.04921%0.214CC..Hα-helixtrans-65.9-36.5174.1-76.2176.8-174131.616.5113.4G333 K334 I375 R394 L395 G396 C400 L573 S575G333-R398 WeakPolarHBondContact CA-O 3.47Å; K334-R398 HydrophobicContact CG-CB 4.13Å; I375-R398 HydrophobicContact CD1-CG 3.74Å; I375-R398 HydrophobicContact CG1-CG 4.21Å; R394-R398 WeakPolarHBondContact O-CG 3.42Å; R394-R398 PolarHBondContact O-N 3.1Å; L395-R398 PolarHBondContact O-N 3.17Å; G396-R398 VanDerWaalsContact C-N 3.33Å; G396-R398 PolarHBondContact O-N 3.35Å; R398-C400 VanDerWaalsContact C-N 3.28Å; R398-L573 PolarHBondContact NH1-O 3.33Å; R398-S575 VanDerWaalsContact CZ-O 3.29Å; R398-S575 PolarHBondContact NH1-O 3.29Å; R398-S575 VanDerWaalsContact NH1-O 3.1Å; R398-S575 PolarHBondContact NH2-O 2.95Å
399A89.3Confident92Very high14 Ų1441.7 Ų41.712%0.11623%0.233CC..Hα-helixtrans-71.8-24.4176.700000113.2N331 K334 L395 G396N331-A399 HydrophobicContact CB-CB 4.44Å; K334-A399 HydrophobicContact CD-CB 4.4Å; K334-A399 HydrophobicContact CG-CB 4.26Å; L395-A399 PolarHBondContact O-N 2.96Å; G396-A399 PolarHBondContact O-N 3.15Å
400C90.1Very high91.9Very high22 Ų2240.8 Ų40.815%0.14922%0.224CC..THydrogen-bonded Turntrans-11325.4-175.6-60.60000113.4G396 L397 R398 G402 N403 H406 A407G396-C400 PolarHBondContact O-N 3.38Å; L397-C400 CarbonylContact O-C 3.01Å; L397-C400 PolarHBondContact O-N 3.26Å; R398-C400 VanDerWaalsContact C-N 3.28Å; C400-G402 PolarHBondContact O-N 3.1Å; C400-N403 WeakPolarHBondContact O-CB 3.49Å; C400-N403 PolarHBondContact O-N 2.91Å; C400-H406 HydrophobicContact CB-CB 3.89Å; C400-A407 HydrophobicContact CB-CB 4.26Å
401D86.7Confident91.9Very high150 Ų15039.5 Ų39.580%0.80221%0.212SC*.THydrogen-bonded Turntrans49.536.3177.6-59.8-46.2000114L397L397-D401 PolarHBondContact O-N 2.92Å
402G87.6Confident92.1Very high19 Ų1940.4 Ų40.420%0.19622%0.22CC..THydrogen-bonded Turntrans77.414.7177.700000115.5K379 L397 C400K379-G402 WeakPolarHBondContact CD-O 3.36Å; K379-G402 PolarHBondContact NZ-O 3.25Å; L397-G402 PolarHBondContact O-N 2.95Å; C400-G402 PolarHBondContact O-N 3.1Å
403N91.9Very high92Very high62 Ų6242.8 Ų42.833%0.33223%0.234SC..  trans-84.2120.1171.3-176.8-37.9000110.9C400 D405 H406 A407C400-N403 WeakPolarHBondContact O-CB 3.49Å; C400-N403 PolarHBondContact O-N 2.91Å; N403-D405 PolarHBondContact OD1-N 2.93Å; N403-H406 HydrophobicContact CB-CB 4.11Å; N403-H406 PolarHBondContact OD1-N 3.45Å; N403-H406 VanDerWaalsContact OD1-N 3.14Å; N403-A407 WeakPolarHBondContact O-CB 3.33Å; N403-A407 PolarHBondContact O-N 2.74Å
404V94.6Very high91.7Very high31 Ų3144.9 Ų44.919%0.18824%0.242CC..Hα-helixtrans-67.8-44.2-175.2179.20000112.1K379 N382 L383 L397 A407 A408K379-V404 HydrophobicContact CB-CG2 3.91Å; K379-V404 HydrophobicContact CD-CG2 4.25Å; K379-V404 HydrophobicContact CG-CG2 3.96Å; N382-V404 HydrophobicContact CB-CG1 4.22Å; L383-V404 HydrophobicContact CD2-CG1 3.8Å; L383-V404 HydrophobicContact CG-CG1 4.15Å; L397-V404 HydrophobicContact CD2-CG2 4.25Å; V404-A407 PolarHBondContact O-N 3.23Å; V404-A408 PolarHBondContact O-N 3.26Å
405D93.7Very high91.5Very high121 Ų12147.1 Ų47.165%0.64725%0.251SS*.Hα-helixtrans-68.7-43.6-176.2-59.6-39.1000111.5N403 A407 A408 T409N403-D405 PolarHBondContact OD1-N 2.93Å; D405-A407 VanDerWaalsContact C-N 3.34Å; D405-A408 PolarHBondContact O-N 2.98Å; D405-T409 PolarHBondContact O-N 3.4Å; D405-T409 VanDerWaalsContact O-N 3.11Å; D405-T409 PolarHBondContact O-OG1 3.02Å
406H92.7Very high91.5Very high119 Ų11953 Ų5355%0.55128%0.278SS*.Hα-helixtrans-64.6-40.7174.6-71.9-169.8000111C400 N403 T409 H410C400-H406 HydrophobicContact CB-CB 3.89Å; N403-H406 HydrophobicContact CB-CB 4.11Å; N403-H406 PolarHBondContact OD1-N 3.45Å; N403-H406 VanDerWaalsContact OD1-N 3.14Å; H406-T409 PolarHBondContact O-N 3.45Å; H406-H410 VanDerWaalsContact O-CB 3.27Å; H406-H410 WeakPolarHBondContact O-CB 3.4Å; H406-H410 PolarHBondContact O-N 3.33Å
407A93.9Very high91.3Very high0 Ų057.9 Ų57.90%030%0.3CS..Hα-helixtrans-62.6-45.3176.700000111.8L383 L397 C400 N403 V404 D405 T409 H410 I411L383-A407 HydrophobicContact CD1-CB 3.98Å; L397-A407 HydrophobicContact CD2-CB 3.92Å; L397-A407 HydrophobicContact CG-CB 4.22Å; C400-A407 HydrophobicContact CB-CB 4.26Å; N403-A407 WeakPolarHBondContact O-CB 3.33Å; N403-A407 PolarHBondContact O-N 2.74Å; V404-A407 PolarHBondContact O-N 3.23Å; D405-A407 VanDerWaalsContact C-N 3.34Å; A407-T409 VanDerWaalsContact C-N 3.33Å; A407-T409 PolarHBondContact O-N 2.92Å; A407-H410 PolarHBondContact O-N 2.73Å; A407-I411 WeakPolarHBondContact O-CB 3.38Å; A407-I411 WeakPolarHBondContact O-CD1 3.36Å; A407-I411 WeakPolarHBondContact O-CG1 3.39Å; A407-I411 PolarHBondContact O-N 2.64Å
408A94.8Very high90.9Very high15 Ų1559.1 Ų59.112%0.12431%0.307CS..Hα-helixtrans-59.3-44177.100000111.9L383 L386 F388 V404 D405 T412L383-A408 HydrophobicContact CD2-CB 3.87Å; L386-A408 HydrophobicContact CD1-CB 4.13Å; F388-A408 HydrophobicContact CE2-CB 3.95Å; F388-A408 HydrophobicContact CZ-CB 4.48Å; V404-A408 PolarHBondContact O-N 3.26Å; D405-A408 PolarHBondContact O-N 2.98Å; A408-T412 WeakPolarHBondContact O-CB 3.17Å; A408-T412 PolarHBondContact O-N 2.91Å; A408-T412 PolarHBondContact O-OG1 3.39Å
409T94.3Very high90.8Very high80 Ų8060.6 Ų60.649%0.49132%0.322SS..Hα-helixtrans-63.9-46.7176.6-52.90000111.1D405 H406 A407 I411 T412 N413D405-T409 PolarHBondContact O-N 3.4Å; D405-T409 VanDerWaalsContact O-N 3.11Å; D405-T409 PolarHBondContact O-OG1 3.02Å; H406-T409 PolarHBondContact O-N 3.45Å; A407-T409 VanDerWaalsContact C-N 3.33Å; A407-T409 PolarHBondContact O-N 2.92Å; T409-I411 PolarHBondContact O-N 3.21Å; T409-T412 PolarHBondContact O-N 3.26Å; T409-N413 VanDerWaalsContact O-CG 3.27Å; T409-N413 PolarHBondContact O-N 3.21Å; T409-N413 PolarHBondContact O-OD1 2.64Å
410H91.6Very high90.8Very high51 Ų5164.5 Ų64.524%0.23634%0.337CS..Hα-helixtrans-62.1-43.9179.1177.9-79.1000112.2N331 H406 A407 T412 R414N331-H410 PolarHBondContact ND2-NE2 2.96Å; H406-H410 VanDerWaalsContact O-CB 3.27Å; H406-H410 WeakPolarHBondContact O-CB 3.4Å; H406-H410 PolarHBondContact O-N 3.33Å; A407-H410 PolarHBondContact O-N 2.73Å; H410-T412 VanDerWaalsContact C-N 3.35Å; H410-R414 VanDerWaalsContact O-CB 3.29Å; H410-R414 WeakPolarHBondContact O-CB 3.49Å; H410-R414 PolarHBondContact O-N 3.49Å
411I92.3Very high90.6Very high8 Ų864.3 Ų64.34%0.04134%0.335CS..Hα-helixtrans-63.1-43.4177.7-64.7160.5000110.4L383 F388 E392 A407 T409 R414 R415L383-I411 HydrophobicContact CD1-CD1 4.17Å; F388-I411 HydrophobicContact CD1-CB 4.23Å; F388-I411 HydrophobicContact CD1-CG2 3.38Å; F388-I411 HydrophobicContact CD2-CD1 4.34Å; F388-I411 HydrophobicContact CE1-CB 4.04Å; F388-I411 HydrophobicContact CE1-CG2 3.48Å; F388-I411 VanDerWaalsContact CE1-CG2 3.48Å; F388-I411 HydrophobicContact CG-CD1 4.27Å; F388-I411 HydrophobicContact CG-CG2 4.12Å; F388-I411 HydrophobicContact CZ-CB 4.38Å; F388-I411 HydrophobicContact CZ-CG2 4.29Å; E392-I411 HydrophobicContact CB-CD1 4.4Å; E392-I411 HydrophobicContact CB-CG2 4.04Å; E392-I411 HydrophobicContact CG-CG2 4.4Å; E392-I411 VanDerWaalsContact O-CD1 3.31Å; E392-I411 WeakPolarHBondContact O-CD1 3.21Å; A407-I411 WeakPolarHBondContact O-CB 3.38Å; A407-I411 WeakPolarHBondContact O-CD1 3.36Å; A407-I411 WeakPolarHBondContact O-CG1 3.39Å; A407-I411 PolarHBondContact O-N 2.64Å; T409-I411 PolarHBondContact O-N 3.21Å; I411-R414 PolarHBondContact O-N 3.36Å; I411-R415 WeakPolarHBondContact O-CG 3.17Å; I411-R415 PolarHBondContact O-N 2.91Å
412T93.2Very high90.5Very high54 Ų5465 Ų6533%0.33133%0.326SS..Hα-helixtrans-62.4-51.5179.5-540000111.3A408 T409 H410 R414 R415 E416A408-T412 WeakPolarHBondContact O-CB 3.17Å; A408-T412 PolarHBondContact O-N 2.91Å; A408-T412 PolarHBondContact O-OG1 3.39Å; T409-T412 PolarHBondContact O-N 3.26Å; H410-T412 VanDerWaalsContact C-N 3.35Å; T412-R414 VanDerWaalsContact C-N 3.26Å; T412-R414 PolarHBondContact O-N 2.74Å; T412-R415 WeakPolarHBondContact O-CB 3.31Å; T412-R415 PolarHBondContact O-N 3.49Å; T412-R415 VanDerWaalsContact O-N 3.15Å; T412-E416 PolarHBondContact O-N 2.95Å; T412-E416 VanDerWaalsContact O-N 3.08Å
413N91.2Very high90.4Very high80 Ų8070.8 Ų70.843%0.42835%0.346SS..Hα-helixtrans-57.6-41.9176.8-67.3-8000111.3T409 R415 E416 E417T409-N413 VanDerWaalsContact O-CG 3.27Å; T409-N413 PolarHBondContact O-N 3.21Å; T409-N413 PolarHBondContact O-OD1 2.64Å; N413-R415 PolarHBondContact O-N 2.91Å; N413-E416 PolarHBondContact O-N 3.1Å; N413-E417 WeakPolarHBondContact O-CG 3.32Å; N413-E417 PolarHBondContact O-N 3.37Å
414R88.1Confident90.1Very high44 Ų4470.9 Ų70.917%0.16634%0.344CS..Hα-helixtrans-66-38.5179.5-172.558.8179.6160.35.3112.6T219 H410 I411 T412 E416 E417 L418T219-R414 PolarHBondContact O-NH2 3.33Å; H410-R414 VanDerWaalsContact O-CB 3.29Å; H410-R414 WeakPolarHBondContact O-CB 3.49Å; H410-R414 PolarHBondContact O-N 3.49Å; I411-R414 PolarHBondContact O-N 3.36Å; T412-R414 VanDerWaalsContact C-N 3.26Å; T412-R414 PolarHBondContact O-N 2.74Å; R414-E416 VanDerWaalsContact C-N 3.33Å; R414-E417 IonicContact CZ-OE2 2.74Å; R414-E417 IonicContact NH1-OE2 2.64Å; R414-E417 PolarHBondContact NH1-OE2 3.44Å; R414-L418 HydrophobicContact CG-CD1 4.15Å; R414-L418 WeakPolarHBondContact O-CB 3.35Å; R414-L418 VanDerWaalsContact O-CG 3.31Å; R414-L418 WeakPolarHBondContact O-CG 3.5Å; R414-L418 PolarHBondContact O-N 2.92Å
415R89.3Confident89.4Confident103 Ų10371.1 Ų71.139%0.38934%0.343SS..Hα-helixtrans-60.7-43.6173.3-78.1179.6172.3-173.6-2.2111.2E392 I411 T412 N413 A419E392-R415 VanDerWaalsContact CD-NH2 3.27Å; E392-R415 IonicContact OE1-CZ 2.64Å; E392-R415 IonicContact OE1-NE 2.64Å; E392-R415 PolarHBondContact OE1-NE 3.29Å; E392-R415 IonicContact OE1-NH2 2.88Å; E392-R415 PolarHBondContact OE1-NH2 2.73Å; E392-R415 VanDerWaalsContact OE1-NH2 3.1Å; E392-R415 IonicContact OE2-CZ 2.74Å; E392-R415 IonicContact OE2-NE 2.73Å; E392-R415 IonicContact OE2-NH2 3.69Å; E392-R415 PolarHBondContact OE2-NH2 2.96Å; I411-R415 WeakPolarHBondContact O-CG 3.17Å; I411-R415 PolarHBondContact O-N 2.91Å; T412-R415 WeakPolarHBondContact O-CB 3.31Å; T412-R415 PolarHBondContact O-N 3.49Å; T412-R415 VanDerWaalsContact O-N 3.15Å; N413-R415 PolarHBondContact O-N 2.91Å; R415-A419 VanDerWaalsContact O-CB 3.29Å; R415-A419 WeakPolarHBondContact O-CB 3.24Å; R415-A419 PolarHBondContact O-N 2.8Å
416E90.9Very high88.8Confident125 Ų12573.3 Ų73.358%0.58435%0.347SS*.Hα-helixtrans-64.8-47.1178.3-69178.8-178.900112.1T412 N413 R414 L418 A419 Q420T412-E416 PolarHBondContact O-N 2.95Å; T412-E416 VanDerWaalsContact O-N 3.08Å; N413-E416 PolarHBondContact O-N 3.1Å; R414-E416 VanDerWaalsContact C-N 3.33Å; E416-L418 PolarHBondContact O-N 3.03Å; E416-A419 PolarHBondContact O-N 3.24Å; E416-Q420 WeakPolarHBondContact O-CB 3.06Å; E416-Q420 PolarHBondContact O-N 3.27Å
417E88.1Confident88.4Confident103 Ų10371.2 Ų71.248%0.48134%0.338SS..Hα-helixtrans-56.5-48.7175.4-75.4176.5-17700112N413 R414 Q420 I421N413-E417 WeakPolarHBondContact O-CG 3.32Å; N413-E417 PolarHBondContact O-N 3.37Å; R414-E417 IonicContact CZ-OE2 2.74Å; R414-E417 IonicContact NH1-OE2 2.64Å; R414-E417 PolarHBondContact NH1-OE2 3.44Å; E417-Q420 WeakPolarHBondContact O-CB 3.49Å; E417-Q420 PolarHBondContact O-N 3.15Å; E417-I421 WeakPolarHBondContact O-CG1 3.07Å; E417-I421 PolarHBondContact O-N 3.42Å
418L84.6Confident87.5Confident28 Ų2875.4 Ų75.415%0.14736%0.356CS..Hα-helixtrans-65.9-38.9179.4-72.9173.8000111.7R414 E416 Q420 I421 R422R414-L418 HydrophobicContact CG-CD1 4.15Å; R414-L418 WeakPolarHBondContact O-CB 3.35Å; R414-L418 VanDerWaalsContact O-CG 3.31Å; R414-L418 WeakPolarHBondContact O-CG 3.5Å; R414-L418 PolarHBondContact O-N 2.92Å; E416-L418 PolarHBondContact O-N 3.03Å; L418-Q420 VanDerWaalsContact C-N 3.29Å; L418-Q420 PolarHBondContact O-N 3.13Å; L418-I421 PolarHBondContact O-N 3.02Å; L418-R422 WeakPolarHBondContact O-CB 3.5Å; L418-R422 VanDerWaalsContact O-CG 3.25Å; L418-R422 WeakPolarHBondContact O-CG 3.35Å; L418-R422 PolarHBondContact O-N 2.74Å
419A88.2Confident86.5Confident43 Ų4378.4 Ų78.436%0.35537%0.366SS..Hα-helixtrans-62.3-39174.500000111.5R415 E416 K423R415-A419 VanDerWaalsContact O-CB 3.29Å; R415-A419 WeakPolarHBondContact O-CB 3.24Å; R415-A419 PolarHBondContact O-N 2.8Å; E416-A419 PolarHBondContact O-N 3.24Å; A419-K423 WeakPolarHBondContact O-CG 3.43Å; A419-K423 PolarHBondContact O-N 2.7Å
420Q89.9Confident85.7Confident96 Ų9681.1 Ų81.145%0.44937%0.368SS..Hα-helixtrans-66.4-47.4176-175.959.420.300111.7E416 E417 L418 R422 K423 E424E416-Q420 WeakPolarHBondContact O-CB 3.06Å; E416-Q420 PolarHBondContact O-N 3.27Å; E417-Q420 WeakPolarHBondContact O-CB 3.49Å; E417-Q420 PolarHBondContact O-N 3.15Å; L418-Q420 VanDerWaalsContact C-N 3.29Å; L418-Q420 PolarHBondContact O-N 3.13Å; Q420-R422 VanDerWaalsContact C-N 3.32Å; Q420-R422 PolarHBondContact O-N 3.45Å; Q420-K423 PolarHBondContact O-N 3.43Å; Q420-E424 WeakPolarHBondContact CG-OE1 3.19Å; Q420-E424 PolarHBondContact NE2-OE1 3.06Å; Q420-E424 WeakPolarHBondContact O-CG 2.93Å; Q420-E424 PolarHBondContact O-N 3.05Å
421I85.6Confident85.1Confident19 Ų1983.3 Ų83.310%0.09737%0.374CS..Hα-helixtrans-58.6-45176.2-67.4166.1000110.8T219 G220 R221 E417 L418 K423 E424 E425T219-I421 WeakPolarHBondContact O-CD1 3.27Å; G220-I421 WeakPolarHBondContact O-CG2 3.17Å; R221-I421 HydrophobicContact CG-CG2 4.44Å; E417-I421 WeakPolarHBondContact O-CG1 3.07Å; E417-I421 PolarHBondContact O-N 3.42Å; L418-I421 PolarHBondContact O-N 3.02Å; I421-K423 VanDerWaalsContact C-N 3.34Å; I421-K423 PolarHBondContact O-N 3.31Å; I421-E424 PolarHBondContact O-N 3.4Å; I421-E425 HydrophobicContact CG2-CG 4.34Å; I421-E425 WeakPolarHBondContact O-CG 3.5Å; I421-E425 PolarHBondContact O-N 3.1Å
422R83.8Confident84.2Confident163 Ų16388 Ų8862%0.61539%0.391SS*.Hα-helixtrans-61-40.7177.3-74.4173.3-176.4171.6-0.5112.3L418 Q420 K426L418-R422 WeakPolarHBondContact O-CB 3.5Å; L418-R422 VanDerWaalsContact O-CG 3.25Å; L418-R422 WeakPolarHBondContact O-CG 3.35Å; L418-R422 PolarHBondContact O-N 2.74Å; Q420-R422 VanDerWaalsContact C-N 3.32Å; Q420-R422 PolarHBondContact O-N 3.45Å; R422-K426 VanDerWaalsContact O-CB 3.27Å; R422-K426 WeakPolarHBondContact O-CB 3.43Å; R422-K426 PolarHBondContact O-N 3.23Å
423K86.6Confident83.3Confident142 Ų14288.1 Ų88.162%0.61739%0.389SS*.Hα-helixtrans-63.8-47.5175.6-75.6174.3-176.7176.90111.3A419 Q420 I421 K426 E427A419-K423 WeakPolarHBondContact O-CG 3.43Å; A419-K423 PolarHBondContact O-N 2.7Å; Q420-K423 PolarHBondContact O-N 3.43Å; I421-K423 VanDerWaalsContact C-N 3.34Å; I421-K423 PolarHBondContact O-N 3.31Å; K423-K426 PolarHBondContact O-N 2.77Å; K423-E427 PolarHBondContact O-N 3.26Å
424E85.4Confident82.7Confident63 Ų6388.8 Ų88.829%0.29439%0.39SS..Hα-helixtrans-61.4-44.9179.1-72.3174.8-164.900112.2Q420 I421 E427 K428Q420-E424 WeakPolarHBondContact CG-OE1 3.19Å; Q420-E424 PolarHBondContact NE2-OE1 3.06Å; Q420-E424 WeakPolarHBondContact O-CG 2.93Å; Q420-E424 PolarHBondContact O-N 3.05Å; I421-E424 PolarHBondContact O-N 3.4Å; E424-E427 PolarHBondContact O-N 3.1Å; E424-K428 WeakPolarHBondContact O-CG 3.42Å; E424-K428 PolarHBondContact O-N 3Å
425E80Confident82.2Confident36 Ų3689 Ų8917%0.16839%0.394CS..Hα-helixtrans-67.1-39.3177.9-70.2-60.9120.600111.7S222 I421 E427 K428 K429S222-E425 WeakPolarHBondContact CB-OE2 3.21Å; S222-E425 PolarHBondContact OG-OE2 3.26Å; I421-E425 HydrophobicContact CG2-CG 4.34Å; I421-E425 WeakPolarHBondContact O-CG 3.5Å; I421-E425 PolarHBondContact O-N 3.1Å; E425-E427 VanDerWaalsContact C-N 3.31Å; E425-E427 PolarHBondContact O-N 2.9Å; E425-K428 PolarHBondContact O-N 3.22Å; E425-K428 WeakPolarHBondContact OE1-CD 3.4Å; E425-K428 IonicContact OE1-NZ 2.73Å; E425-K428 PolarHBondContact OE1-NZ 3.47Å; E425-K429 WeakPolarHBondContact O-CB 3.37Å; E425-K429 PolarHBondContact O-N 2.81Å
426K80.9Confident81.6Confident167 Ų16785.7 Ų85.773%0.72638%0.384SS*.Hα-helixtrans-61.4-40.7173.8-172.6175.1-177.9176.30111.5R422 K423 K429 R430R422-K426 VanDerWaalsContact O-CB 3.27Å; R422-K426 WeakPolarHBondContact O-CB 3.43Å; R422-K426 PolarHBondContact O-N 3.23Å; K423-K426 PolarHBondContact O-N 2.77Å; K426-K429 PolarHBondContact O-N 3.3Å; K426-R430 PolarHBondContact O-N 2.86Å
427E83Confident81Confident76 Ų7688.4 Ų88.436%0.35539%0.389SS..Hα-helixtrans-69.1-45177.5-169.5176.4177.600112.2K423 E424 E425 K429 R430 R431K423-E427 PolarHBondContact O-N 3.26Å; E424-E427 PolarHBondContact O-N 3.1Å; E425-E427 VanDerWaalsContact C-N 3.31Å; E425-E427 PolarHBondContact O-N 2.9Å; E427-K429 PolarHBondContact O-N 3.27Å; E427-R430 WeakPolarHBondContact O-CB 3.35Å; E427-R430 PolarHBondContact O-N 2.86Å; E427-R430 VanDerWaalsContact O-N 3.16Å; E427-R430 IonicContact OE1-NH2 3.93Å; E427-R431 WeakPolarHBondContact O-CG 3.44Å; E427-R431 PolarHBondContact O-N 3.32Å; E427-R431 IonicContact OE1-CZ 3.83Å; E427-R431 IonicContact OE1-NE 3.89Å; E427-R431 PolarHBondContact OE1-NE 2.89Å; E427-R431 IonicContact OE1-NH2 2.71Å; E427-R431 PolarHBondContact OE1-NH2 2.96Å
428K76.9Confident80.7Confident88 Ų8889.9 Ų89.938%0.38339%0.394SS..Hα-helixtrans-56-40.9172.8-72.5173.4-163.61640111.2E424 E425 R431 R432E424-K428 WeakPolarHBondContact O-CG 3.42Å; E424-K428 PolarHBondContact O-N 3Å; E425-K428 PolarHBondContact O-N 3.22Å; E425-K428 WeakPolarHBondContact OE1-CD 3.4Å; E425-K428 IonicContact OE1-NZ 2.73Å; E425-K428 PolarHBondContact OE1-NZ 3.47Å; K428-R431 PolarHBondContact O-N 3.29Å; K428-R432 WeakPolarHBondContact O-CG 3.4Å; K428-R432 PolarHBondContact O-N 2.93Å
429K72.6Confident80.4Confident77 Ų7789 Ų8934%0.33539%0.389SS..Hα-helixtrans-64.1-46.2176.8-173.1176.9-178.3178.30111.6E425 K426 E427 R431 R432 L433E425-K429 WeakPolarHBondContact O-CB 3.37Å; E425-K429 PolarHBondContact O-N 2.81Å; K426-K429 PolarHBondContact O-N 3.3Å; E427-K429 PolarHBondContact O-N 3.27Å; K429-R431 PolarHBondContact O-N 2.95Å; K429-R432 PolarHBondContact O-N 3.33Å; K429-L433 HydrophobicContact CG-CD1 4.3Å; K429-L433 PolarHBondContact O-N 2.74Å; K429-L433 VanDerWaalsContact O-N 3.11Å
430R77.9Confident80.1Confident138 Ų13893.1 Ų93.152%0.52140%0.399SS..Hα-helixtrans-56.6-49.6175.7-175.3-177.163.9164.5-1.2111.3K426 E427 R432 L433 E434K426-R430 PolarHBondContact O-N 2.86Å; E427-R430 WeakPolarHBondContact O-CB 3.35Å; E427-R430 PolarHBondContact O-N 2.86Å; E427-R430 VanDerWaalsContact O-N 3.16Å; E427-R430 IonicContact OE1-NH2 3.93Å; R430-R432 VanDerWaalsContact C-N 3.34Å; R430-R432 PolarHBondContact O-N 3.42Å; R430-L433 PolarHBondContact O-N 3.17Å; R430-L433 VanDerWaalsContact O-N 3.14Å; R430-E434 WeakPolarHBondContact CG-OE1 3.07Å; R430-E434 IonicContact NE-OE1 2.75Å; R430-E434 PolarHBondContact O-N 3.42Å
431R78.3Confident79.6Confident97 Ų9792 Ų9237%0.36641%0.413SS..Hα-helixtrans-59.9-41.2178.4-67-179.5-170.4-165.32.2112.3E427 K428 K429 L433 E434 N435E427-R431 WeakPolarHBondContact O-CG 3.44Å; E427-R431 PolarHBondContact O-N 3.32Å; E427-R431 IonicContact OE1-CZ 3.83Å; E427-R431 IonicContact OE1-NE 3.89Å; E427-R431 PolarHBondContact OE1-NE 2.89Å; E427-R431 IonicContact OE1-NH2 2.71Å; E427-R431 PolarHBondContact OE1-NH2 2.96Å; K428-R431 PolarHBondContact O-N 3.29Å; K429-R431 PolarHBondContact O-N 2.95Å; R431-L433 VanDerWaalsContact C-N 3.33Å; R431-L433 PolarHBondContact O-N 3Å; R431-E434 PolarHBondContact O-N 3.07Å; R431-N435 WeakPolarHBondContact O-CB 3.17Å; R431-N435 VanDerWaalsContact O-CG 3.25Å; R431-N435 PolarHBondContact O-N 3.09Å; R431-N435 PolarHBondContact O-ND2 2.78Å
432R73.6Confident79.3Confident106 Ų10696.5 Ų96.540%0.444%0.435SS..Hα-helixtrans-60-42.2175.7-75.1176.2-172.6169.88112.1K428 K429 R430 N435 I436K428-R432 WeakPolarHBondContact O-CG 3.4Å; K428-R432 PolarHBondContact O-N 2.93Å; K429-R432 PolarHBondContact O-N 3.33Å; R430-R432 VanDerWaalsContact C-N 3.34Å; R430-R432 PolarHBondContact O-N 3.42Å; R432-N435 PolarHBondContact O-N 3.16Å; R432-I436 VanDerWaalsContact O-CG1 3.3Å; R432-I436 WeakPolarHBondContact O-CG1 3.17Å; R432-I436 PolarHBondContact O-N 3.39Å
433L74.2Confident79.1Confident57 Ų5792 Ų9230%0.29844%0.439SS..Hα-helixtrans-68.9-41.8179.5-72.8160.1000112.1P207 K429 R430 R431 N435 I436 R437P207-L433 HydrophobicContact CG-CD1 3.48Å; P207-L433 VanDerWaalsContact CG-CD1 3.48Å; P207-L433 HydrophobicContact CG-CD2 4.34Å; K429-L433 HydrophobicContact CG-CD1 4.3Å; K429-L433 PolarHBondContact O-N 2.74Å; K429-L433 VanDerWaalsContact O-N 3.11Å; R430-L433 PolarHBondContact O-N 3.17Å; R430-L433 VanDerWaalsContact O-N 3.14Å; R431-L433 VanDerWaalsContact C-N 3.33Å; R431-L433 PolarHBondContact O-N 3Å; L433-N435 VanDerWaalsContact C-N 3.32Å; L433-N435 PolarHBondContact O-N 3.17Å; L433-I436 PolarHBondContact O-N 2.75Å; L433-R437 WeakPolarHBondContact O-CB 3.3Å; L433-R437 WeakPolarHBondContact O-CG 3.48Å; L433-R437 PolarHBondContact O-N 2.91Å
434E80.1Confident78.6Confident94 Ų9490.2 Ų90.244%0.43943%0.429SS..Hα-helixtrans-58.6-45.5174-72.9166.8-175.800110.9R430 R431 I436 R437 F438R430-E434 WeakPolarHBondContact CG-OE1 3.07Å; R430-E434 IonicContact NE-OE1 2.75Å; R430-E434 PolarHBondContact O-N 3.42Å; R431-E434 PolarHBondContact O-N 3.07Å; E434-I436 PolarHBondContact O-N 3.43Å; E434-R437 PolarHBondContact O-N 3.36Å; E434-F438 WeakPolarHBondContact O-CB 3.37Å; E434-F438 PolarHBondContact O-N 3.34Å
435N76.3Confident78.3Confident48 Ų4890.7 Ų90.726%0.25744%0.439SS..Hα-helixtrans-62.2-40.8175.9-70.2-13.2000112.7R431 R432 L433 F438 L439 L453R431-N435 WeakPolarHBondContact O-CB 3.17Å; R431-N435 VanDerWaalsContact O-CG 3.25Å; R431-N435 PolarHBondContact O-N 3.09Å; R431-N435 PolarHBondContact O-ND2 2.78Å; R432-N435 PolarHBondContact O-N 3.16Å; L433-N435 VanDerWaalsContact C-N 3.32Å; L433-N435 PolarHBondContact O-N 3.17Å; N435-F438 PolarHBondContact O-N 2.9Å; N435-L439 WeakPolarHBondContact O-CG 3.36Å; N435-L439 PolarHBondContact O-N 3.13Å; N435-L453 HydrophobicContact CB-CD1 4.1Å; N435-L453 HydrophobicContact CB-CD2 4.01Å
436I76.7Confident77.8Confident33 Ų3391.5 Ų91.517%0.16945%0.447CS..Hα-helixtrans-65.2-43.4175.6-68.9167.1000110.6R432 L433 E434 F438 L439 K440 Q450 L453R432-I436 VanDerWaalsContact O-CG1 3.3Å; R432-I436 WeakPolarHBondContact O-CG1 3.17Å; R432-I436 PolarHBondContact O-N 3.39Å; L433-I436 PolarHBondContact O-N 2.75Å; E434-I436 PolarHBondContact O-N 3.43Å; I436-F438 VanDerWaalsContact C-N 3.33Å; I436-F438 PolarHBondContact O-N 3.07Å; I436-L439 PolarHBondContact O-N 2.91Å; I436-K440 WeakPolarHBondContact O-CB 3.42Å; I436-K440 PolarHBondContact O-N 3.43Å; I436-Q450 HydrophobicContact CD1-CG 4.11Å; I436-Q450 HydrophobicContact CG1-CG 4.48Å; I436-L453 HydrophobicContact CD1-CD1 4.41Å; I436-L453 HydrophobicContact CG1-CD1 3.5Å
437R79.1Confident77.2Confident182 Ų18289.6 Ų89.669%0.68744%0.44SS*.Hα-helixtrans-61.9-42.2176.6-74.8179-179.2-177.30.5111.3L433 E434 K440 G441L433-R437 WeakPolarHBondContact O-CB 3.3Å; L433-R437 WeakPolarHBondContact O-CG 3.48Å; L433-R437 PolarHBondContact O-N 2.91Å; E434-R437 PolarHBondContact O-N 3.36Å; R437-K440 PolarHBondContact O-N 2.83Å; R437-G441 PolarHBondContact O-N 3.19Å
438F80.8Confident76.6Confident134 Ų13487.3 Ų87.359%0.58844%0.435SS*.Hα-helixtrans-60.8-49.9176179.7-100.1000111.8E434 N435 I436 K440 G441 M442E434-F438 WeakPolarHBondContact O-CB 3.37Å; E434-F438 PolarHBondContact O-N 3.34Å; N435-F438 PolarHBondContact O-N 2.9Å; I436-F438 VanDerWaalsContact C-N 3.33Å; I436-F438 PolarHBondContact O-N 3.07Å; F438-K440 VanDerWaalsContact C-N 3.3Å; F438-K440 PolarHBondContact O-N 3.46Å; F438-G441 CarbonylContact O-C 3.53Å; F438-G441 WeakPolarHBondContact O-CA 3.33Å; F438-G441 PolarHBondContact O-N 3.4Å; F438-M442 HydrophobicContact CD1-SD 3.92Å; F438-M442 HydrophobicContact CE1-CG 4.22Å; F438-M442 HydrophobicContact CE1-SD 3.32Å; F438-M442 WeakPolarHBondContact CE1-SD 3.38Å; F438-M442 HydrophobicContact CZ-CG 4.4Å; F438-M442 HydrophobicContact CZ-SD 3.85Å; F438-M442 PolarHBondContact O-N 3.44Å
439L79.8Confident76.4Confident9 Ų983.1 Ų83.15%0.04742%0.416CS..Hα-helixtrans-62.6-36.6177-71.1170.2000112.3N435 I436 G441 M442 G443 Y444 A449 L453N435-L439 WeakPolarHBondContact O-CG 3.36Å; N435-L439 PolarHBondContact O-N 3.13Å; I436-L439 PolarHBondContact O-N 2.91Å; L439-G441 VanDerWaalsContact C-N 3.33Å; L439-M442 HydrophobicContact CD2-SD 4.36Å; L439-M442 WeakPolarHBondContact O-CB 3.41Å; L439-M442 PolarHBondContact O-N 2.91Å; L439-G443 PolarHBondContact O-N 3.32Å; L439-Y444 HydrophobicContact CB-CD2 4.37Å; L439-Y444 HydrophobicContact CD2-CD2 4.09Å; L439-Y444 HydrophobicContact CD2-CE2 4.29Å; L439-Y444 WeakPolarHBondContact O-CB 3.37Å; L439-Y444 WeakPolarHBondContact O-CD2 3.5Å; L439-Y444 PolarHBondContact O-N 2.93Å; L439-Y444 VanDerWaalsContact O-N 3.12Å; L439-A449 HydrophobicContact CB-CB 3.5Å; L439-A449 HydrophobicContact CD1-CB 3.79Å; L439-A449 WeakPolarHBondContact CD1-O 3.48Å; L439-A449 HydrophobicContact CG-CB 4.29Å; L439-L453 HydrophobicContact CD1-CD1 4.08Å; L439-L453 HydrophobicContact CD1-CD2 4.44Å; L439-L453 HydrophobicContact CD1-CG 3.93Å
440K80.6Confident76Confident131 Ų13180.9 Ų80.957%0.5741%0.407SS*.Hα-helixtrans-63.5-40.4172.4-170.4-178.7178.5-176.40111.6I436 R437 F438 M442 G443 T446I436-K440 WeakPolarHBondContact O-CB 3.42Å; I436-K440 PolarHBondContact O-N 3.43Å; R437-K440 PolarHBondContact O-N 2.83Å; F438-K440 VanDerWaalsContact C-N 3.3Å; F438-K440 PolarHBondContact O-N 3.46Å; K440-M442 PolarHBondContact O-N 3.38Å; K440-G443 PolarHBondContact O-N 3.33Å; K440-T446 HydrophobicContact CD-CG2 4.23Å
441G80.7Confident75.5Confident71 Ų7180 Ų8073%0.73241%0.409SS*.Hα-helixtrans-62.3-29.4173.500000113.5R437 F438 L439 G443R437-G441 PolarHBondContact O-N 3.19Å; F438-G441 CarbonylContact O-C 3.53Å; F438-G441 WeakPolarHBondContact O-CA 3.33Å; F438-G441 PolarHBondContact O-N 3.4Å; L439-G441 VanDerWaalsContact C-N 3.33Å; G441-G443 PolarHBondContact O-N 2.99Å
442M79.4Confident75.1Confident114 Ų11477.6 Ų77.656%0.56240%0.403SS*.THydrogen-bonded Turntrans-780.5172.2-64.8179.871.300114F438 L439 K440 Y444F438-M442 HydrophobicContact CD1-SD 3.92Å; F438-M442 HydrophobicContact CE1-CG 4.22Å; F438-M442 HydrophobicContact CE1-SD 3.32Å; F438-M442 WeakPolarHBondContact CE1-SD 3.38Å; F438-M442 HydrophobicContact CZ-CG 4.4Å; F438-M442 HydrophobicContact CZ-SD 3.85Å; F438-M442 PolarHBondContact O-N 3.44Å; L439-M442 HydrophobicContact CD2-SD 4.36Å; L439-M442 WeakPolarHBondContact O-CB 3.41Å; L439-M442 PolarHBondContact O-N 2.91Å; K440-M442 PolarHBondContact O-N 3.38Å; M442-Y444 HydrophobicContact CB-CD2 3.97Å; M442-Y444 HydrophobicContact CB-CE2 4.09Å; M442-Y444 HydrophobicContact CE-CE2 4.44Å
443G79Confident74.9Confident68 Ų6873.2 Ų73.270%0.70139%0.387SS*.THydrogen-bonded Turntrans93.13.517800000115.2L439 K440 G441L439-G443 PolarHBondContact O-N 3.32Å; K440-G443 PolarHBondContact O-N 3.33Å; G441-G443 PolarHBondContact O-N 2.99Å
444Y75.9Confident74.4Confident105 Ų10576 Ų7641%0.41240%0.402SS..  trans-72.5140.8172.9-65.9-82.6000110.9L439 M442 A448 I452L439-Y444 HydrophobicContact CB-CD2 4.37Å; L439-Y444 HydrophobicContact CD2-CD2 4.09Å; L439-Y444 HydrophobicContact CD2-CE2 4.29Å; L439-Y444 WeakPolarHBondContact O-CB 3.37Å; L439-Y444 WeakPolarHBondContact O-CD2 3.5Å; L439-Y444 PolarHBondContact O-N 2.93Å; L439-Y444 VanDerWaalsContact O-N 3.12Å; M442-Y444 HydrophobicContact CB-CD2 3.97Å; M442-Y444 HydrophobicContact CB-CE2 4.09Å; M442-Y444 HydrophobicContact CE-CE2 4.44Å; Y444-A448 HydrophobicContact CD1-CB 4.42Å; Y444-I452 HydrophobicContact CD1-CD1 3.78Å; Y444-I452 HydrophobicContact CE1-CD1 3.79Å; Y444-I452 HydrophobicContact CG-CD1 4.26Å
445S78.3Confident73.4Confident73 Ų7375.5 Ų75.551%0.5141%0.408SS..  trans-63.2152.5167.371.60000110H447 A448 A449S445-H447 PolarHBondContact O-N 2.8Å; S445-A448 PolarHBondContact O-N 2.83Å; S445-A448 WeakPolarHBondContact OG-CB 3.5Å; S445-A448 PolarHBondContact OG-N 3.13Å; S445-A449 PolarHBondContact O-N 2.79Å
446T69.1Low72.5Confident54 Ų5477.5 Ų77.533%0.33142%0.419SS..Hα-helixtrans-54.6-39.718046.30000112.3K440 Q450K440-T446 HydrophobicContact CD-CG2 4.23Å; T446-Q450 VanDerWaalsContact O-CG 3.29Å; T446-Q450 WeakPolarHBondContact O-CG 3.16Å; T446-Q450 PolarHBondContact O-N 3.35Å; T446-Q450 VanDerWaalsContact O-N 3.17Å
447H69.3Low71.3Confident127 Ų12778.8 Ų78.859%0.58843%0.43SS*.Hα-helixtrans-66.6-42.8176.3-173.2-82.6000112.4S445 Q450 Q451S445-H447 PolarHBondContact O-N 2.8Å; H447-Q450 PolarHBondContact O-N 2.73Å; H447-Q451 PolarHBondContact O-N 2.95Å
448A70.2Confident69.9Low28 Ų2877.8 Ų77.823%0.23143%0.433CS..Hα-helixtrans-65.9-42.7177.600000111.8Y444 S445 Q450 Q451 I452Y444-A448 HydrophobicContact CD1-CB 4.42Å; S445-A448 PolarHBondContact O-N 2.83Å; S445-A448 WeakPolarHBondContact OG-CB 3.5Å; S445-A448 PolarHBondContact OG-N 3.13Å; A448-Q450 VanDerWaalsContact C-N 3.29Å; A448-Q450 PolarHBondContact O-N 3.5Å; A448-Q451 PolarHBondContact O-N 3.34Å; A448-I452 WeakPolarHBondContact O-CD1 3.33Å; A448-I452 VanDerWaalsContact O-CG1 3.24Å; A448-I452 WeakPolarHBondContact O-CG1 3.25Å; A448-I452 PolarHBondContact O-N 3.37Å
449A72Confident68.4Low0 Ų074.5 Ų74.50%042%0.42CS..Hα-helixtrans-58.3-41176.200000112.4L439 S445 L453L439-A449 HydrophobicContact CB-CB 3.5Å; L439-A449 HydrophobicContact CD1-CB 3.79Å; L439-A449 WeakPolarHBondContact CD1-O 3.48Å; L439-A449 HydrophobicContact CG-CB 4.29Å; S445-A449 PolarHBondContact O-N 2.79Å; A449-L453 WeakPolarHBondContact O-CG 3.29Å; A449-L453 PolarHBondContact O-N 3.43Å; A449-L453 VanDerWaalsContact O-N 3.13Å
450Q65.8Low66.9Low30 Ų3077.5 Ų77.514%0.1443%0.431CS..Hα-helixtrans-67.1-43.7176.3-74173-6.200112.4I436 T446 H447 A448 I452 L453 L454I436-Q450 HydrophobicContact CD1-CG 4.11Å; I436-Q450 HydrophobicContact CG1-CG 4.48Å; T446-Q450 VanDerWaalsContact O-CG 3.29Å; T446-Q450 WeakPolarHBondContact O-CG 3.16Å; T446-Q450 PolarHBondContact O-N 3.35Å; T446-Q450 VanDerWaalsContact O-N 3.17Å; H447-Q450 PolarHBondContact O-N 2.73Å; A448-Q450 VanDerWaalsContact C-N 3.29Å; A448-Q450 PolarHBondContact O-N 3.5Å; Q450-I452 VanDerWaalsContact C-N 3.3Å; Q450-I452 PolarHBondContact O-N 3.27Å; Q450-L453 PolarHBondContact O-N 2.84Å; Q450-L453 VanDerWaalsContact O-N 3.17Å; Q450-L454 VanDerWaalsContact O-CD1 3.23Å; Q450-L454 WeakPolarHBondContact O-CD1 3.4Å; Q450-L454 PolarHBondContact O-N 3.44Å
451Q67.3Low64.9Low118 Ų11879.3 Ų79.355%0.55143%0.434SS*.Hα-helixtrans-62.2-40.7179-162.3170.43.200111.1H447 A448 L453 L454 S455H447-Q451 PolarHBondContact O-N 2.95Å; A448-Q451 PolarHBondContact O-N 3.34Å; Q451-L453 PolarHBondContact O-N 3.3Å; Q451-L454 PolarHBondContact O-N 2.84Å; Q451-S455 WeakPolarHBondContact O-CB 3.18Å; Q451-S455 PolarHBondContact O-N 2.97Å; Q451-S455 PolarHBondContact O-OG 3.45Å; Q451-S455 VanDerWaalsContact O-OG 3.11Å
452I69.3Low63Low48 Ų4881.8 Ų81.825%0.24643%0.43CS..Hα-helixtrans-59.8-44.9173.6-67163.4000111.2Y444 A448 Q450 L454 S455 N456Y444-I452 HydrophobicContact CD1-CD1 3.78Å; Y444-I452 HydrophobicContact CE1-CD1 3.79Å; Y444-I452 HydrophobicContact CG-CD1 4.26Å; A448-I452 WeakPolarHBondContact O-CD1 3.33Å; A448-I452 VanDerWaalsContact O-CG1 3.24Å; A448-I452 WeakPolarHBondContact O-CG1 3.25Å; A448-I452 PolarHBondContact O-N 3.37Å; Q450-I452 VanDerWaalsContact C-N 3.3Å; Q450-I452 PolarHBondContact O-N 3.27Å; I452-L454 VanDerWaalsContact C-N 3.35Å; I452-L454 PolarHBondContact O-N 3.18Å; I452-S455 PolarHBondContact O-N 3.5Å; I452-N456 PolarHBondContact O-N 3.38Å
453L68.3Low61.2Low14 Ų1483.9 Ų83.97%0.07344%0.443CS..Hα-helixtrans-69.4-28.8178.5-73.3168.2000113.6N435 I436 L439 A449 Q450 Q451 W460N435-L453 HydrophobicContact CB-CD1 4.1Å; N435-L453 HydrophobicContact CB-CD2 4.01Å; I436-L453 HydrophobicContact CD1-CD1 4.41Å; I436-L453 HydrophobicContact CG1-CD1 3.5Å; L439-L453 HydrophobicContact CD1-CD1 4.08Å; L439-L453 HydrophobicContact CD1-CD2 4.44Å; L439-L453 HydrophobicContact CD1-CG 3.93Å; A449-L453 WeakPolarHBondContact O-CG 3.29Å; A449-L453 PolarHBondContact O-N 3.43Å; A449-L453 VanDerWaalsContact O-N 3.13Å; Q450-L453 PolarHBondContact O-N 2.84Å; Q450-L453 VanDerWaalsContact O-N 3.17Å; Q451-L453 PolarHBondContact O-N 3.3Å; L453-W460 PolarHBondContact O-NE1 3.42Å
454L64.9Low59.1Low115 Ų11586.4 Ų86.460%0.60244%0.441SS*.Hα-helixtrans-73.1-40.8173-9883.9000111.7Q450 Q451 I452Q450-L454 VanDerWaalsContact O-CD1 3.23Å; Q450-L454 WeakPolarHBondContact O-CD1 3.4Å; Q450-L454 PolarHBondContact O-N 3.44Å; Q451-L454 PolarHBondContact O-N 2.84Å; I452-L454 VanDerWaalsContact C-N 3.35Å; I452-L454 PolarHBondContact O-N 3.18Å
455S59.3Low57.1Low83 Ų8386.6 Ų86.658%0.5846%0.458SS*.Hα-helixtrans-75.4-26.9-177.5-640000113.6Q451 I452 P457Q451-S455 WeakPolarHBondContact O-CB 3.18Å; Q451-S455 PolarHBondContact O-N 2.97Å; Q451-S455 PolarHBondContact O-OG 3.45Å; Q451-S455 VanDerWaalsContact O-OG 3.11Å; I452-S455 PolarHBondContact O-N 3.5Å; S455-P457 WeakPolarHBondContact O-CD 3.32Å
456N57.9Low54.9Low91 Ų9189.2 Ų89.249%0.48747%0.466SS..  trans-123.385.6-178.7-72.9-25000112.7I452 Q458 M459I452-N456 PolarHBondContact O-N 3.38Å; N456-Q458 PolarHBondContact O-N 2.94Å; N456-M459 HydrophobicContact CB-CB 4.47Å; N456-M459 HydrophobicContact CB-CG 4.22Å; N456-M459 WeakPolarHBondContact O-CB 3.45Å; N456-M459 PolarHBondContact O-N 3.47Å
457P51.4Low53.4Low59 Ų5993 Ų9338%0.38349%0.492SS..G310 helixtrans-60.2-24.9177.3-24.834.6000115S455 M459 W460S455-P457 WeakPolarHBondContact O-CD 3.32Å; P457-M459 VanDerWaalsContact C-N 3.3Å; P457-M459 PolarHBondContact O-N 3.34Å; P457-W460 HydrophobicContact CB-CD2 4.48Å; P457-W460 HydrophobicContact CB-CE3 4.32Å; P457-W460 HydrophobicContact CB-CH2 3.5Å; P457-W460 HydrophobicContact CB-CZ2 3.8Å; P457-W460 HydrophobicContact CB-CZ3 3.87Å; P457-W460 HydrophobicContact CG-CH2 4.03Å; P457-W460 HydrophobicContact CG-CZ2 4.2Å; P457-W460 WeakPolarHBondContact O-CB 3.48Å; P457-W460 VanDerWaalsContact O-CD2 3.25Å; P457-W460 VanDerWaalsContact O-CG 3.24Å; P457-W460 PolarHBondContact O-N 2.89Å
458Q48Very low51.6Low161 Ų16194.5 Ų94.575%0.75250%0.499SS*.G310 helixtrans-73.1-22.8-178.7-66.9-178-8.800112.7N456 W460 W461N456-Q458 PolarHBondContact O-N 2.94Å; Q458-W460 PolarHBondContact O-N 3.01Å; Q458-W460 VanDerWaalsContact O-N 3.17Å; Q458-W461 PolarHBondContact O-N 2.94Å; Q458-W461 VanDerWaalsContact O-N 3.15Å
459M50Low50Low66 Ų6699.5 Ų99.533%0.32553%0.526SS..G310 helixtrans-65.6-13172.5-85.3-84.7-73.800113.2N456 P457 W461 L462N456-M459 HydrophobicContact CB-CB 4.47Å; N456-M459 HydrophobicContact CB-CG 4.22Å; N456-M459 WeakPolarHBondContact O-CB 3.45Å; N456-M459 PolarHBondContact O-N 3.47Å; P457-M459 VanDerWaalsContact C-N 3.3Å; P457-M459 PolarHBondContact O-N 3.34Å; M459-W461 PolarHBondContact O-N 3.17Å; M459-L462 HydrophobicContact CG-CD1 4.29Å; M459-L462 HydrophobicContact SD-CD1 3.8Å
460W47.3Very low48.2Very low72 Ų72106.2 Ų106.227%0.27356%0.562SS.*G310 helixtrans-74.4-13.5175.4-50.5-15.8000112.9L453 P457 Q458L453-W460 PolarHBondContact O-NE1 3.42Å; P457-W460 HydrophobicContact CB-CD2 4.48Å; P457-W460 HydrophobicContact CB-CE3 4.32Å; P457-W460 HydrophobicContact CB-CH2 3.5Å; P457-W460 HydrophobicContact CB-CZ2 3.8Å; P457-W460 HydrophobicContact CB-CZ3 3.87Å; P457-W460 HydrophobicContact CG-CH2 4.03Å; P457-W460 HydrophobicContact CG-CZ2 4.2Å; P457-W460 WeakPolarHBondContact O-CB 3.48Å; P457-W460 VanDerWaalsContact O-CD2 3.25Å; P457-W460 VanDerWaalsContact O-CG 3.24Å; P457-W460 PolarHBondContact O-N 2.89Å; Q458-W460 PolarHBondContact O-N 3.01Å; Q458-W460 VanDerWaalsContact O-N 3.17Å
461W39.8Very low47Very low168 Ų168112.1 Ų112.164%0.63660%0.595SS**G310 helixtrans-110.10.9-174.1-55.596.6000113.6Q458 M459 N463 D464Q458-W461 PolarHBondContact O-N 2.94Å; Q458-W461 VanDerWaalsContact O-N 3.15Å; M459-W461 PolarHBondContact O-N 3.17Å; W461-N463 PolarHBondContact O-N 3.17Å; W461-D464 PolarHBondContact O-N 3.49Å
462L41.5Very low45.5Very low123 Ų123116.9 Ų116.964%0.64461%0.608SS**THydrogen-bonded Turntrans-67.92.5-173.6-110.6105.2000115.1M459M459-L462 HydrophobicContact CG-CD1 4.29Å; M459-L462 HydrophobicContact SD-CD1 3.8Å
463N41.3Very low44.4Very low158 Ų158124 Ų12485%0.84564%0.64SS**THydrogen-bonded Turntrans-115.311.3177.2-131.231.5000114.4W461 S465W461-N463 PolarHBondContact O-N 3.17Å; N463-S465 VanDerWaalsContact C-N 3.26Å; N463-S465 PolarHBondContact O-N 3.3Å
464D34.1Very low43.4Very low122 Ų122131.1 Ų131.165%0.65267%0.673SS**  trans-9015.7175.4-136.612.3000113.2W461W461-D464 PolarHBondContact O-N 3.49Å
465S34.1Very low42.9Very low108 Ų108130 Ų13076%0.75568%0.675SS**SBendtrans-98.486.5168-58.10000109N463N463-S465 VanDerWaalsContact C-N 3.26Å; N463-S465 PolarHBondContact O-N 3.3Å
466N32.3Very low43.3Very low128 Ų128126.9 Ų126.968%0.68465%0.652SS**  trans51.2124.4165.7-81.60.1000119.2E468N466-E468 PolarHBondContact O-N 3.2Å
467P36.8Very low44.1Very low135 Ų135125.5 Ų125.588%0.87765%0.65SS**SBendtrans-81.944.8166.438.4-34000111.2
468E33.1Very low45.3Very low158 Ų158128.4 Ų128.474%0.73866%0.659SS**  trans-140.465.6-178.2-78.2-88.516400108.3N466N466-E468 PolarHBondContact O-N 3.2Å
469T35.6Very low46.9Very low132 Ų132128 Ų12881%0.8166%0.656SS**  trans-162.591.5143.120.20000108.9
470D33.9Very low48.4Very low141 Ų141126.7 Ų126.775%0.75465%0.651SS**  trans-49.6148.3165.8-138.3-20.4000112.1R472D470-R472 PolarHBondContact O-N 2.97Å
471N39.9Very low50.1Low154 Ų154123.7 Ų123.782%0.82464%0.64SS**SBendtrans-20.498.7167-72.4-55.9000115.9
472R37.5Very low52.1Low218 Ų218119.8 Ų119.882%0.82363%0.632SS**  trans-140.2129.8151.2-71.4-165.2175.9-153.5-1.9110.2D470 E474D470-R472 PolarHBondContact O-N 2.97Å; R472-E474 HydrophobicContact CB-CG 4.39Å; R472-E474 PolarHBondContact O-N 3.03Å
473Q45.9Very low54.1Low199 Ų199121.6 Ų121.693%0.9363%0.63SS**  trans-58.288157.7-74.6162.6-34.600107.3S475Q473-S475 PolarHBondContact O-N 3.37Å
474E46.2Very low55.9Low163 Ų163114 Ų11476%0.76259%0.59SS**  trans-76.4115.4173.3-77.5-171.9160.300108.4R472R472-E474 HydrophobicContact CB-CG 4.39Å; R472-E474 PolarHBondContact O-N 3.03Å
475S55.8Low58.4Low92 Ų92111 Ų11164%0.64358%0.576SS**PPolyproline II helixtrans-54.2137.3163.346.40000109.1Q473 S477Q473-S475 PolarHBondContact O-N 3.37Å; S475-S477 PolarHBondContact O-N 2.96Å
476P66.7Low60.9Low16 Ų16115.9 Ų115.910%0.10458%0.579CS.*PPolyproline II helixtrans-56.6133-178.523.5-32.8000110.6Q478 I481 E495 L498P476-Q478 PolarHBondContact O-N 3.03Å; P476-I481 HydrophobicContact CB-CG1 4.44Å; P476-I481 HydrophobicContact CG-CD1 4.21Å; P476-I481 HydrophobicContact CG-CG1 4.48Å; P476-E495 HydrophobicContact CG-CG 3.65Å; P476-L498 HydrophobicContact CB-CB 3.67Å; P476-L498 HydrophobicContact CB-CD1 4.29Å; P476-L498 HydrophobicContact CG-CB 4.23Å
477S75.2Confident63.1Low62 Ų62115.3 Ų115.343%0.43457%0.573SS.*PPolyproline II helixtrans-58.8133.5-179.2590000110.9S475 E479 N480 I481S475-S477 PolarHBondContact O-N 2.96Å; S477-E479 PolarHBondContact O-N 3.11Å; S477-N480 WeakPolarHBondContact O-CB 3.2Å; S477-N480 PolarHBondContact O-N 3.13Å; S477-N480 PolarHBondContact OG-ND2 2.95Å; S477-I481 PolarHBondContact O-N 3.45Å
478Q77.2Confident65.2Low121 Ų121112.1 Ų112.157%0.56557%0.565SS**Hα-helixtrans-51.9-36.2-175.8-170.561.239.600113.3P476 N480 I481 D482P476-Q478 PolarHBondContact O-N 3.03Å; Q478-N480 VanDerWaalsContact C-N 3.27Å; Q478-N480 PolarHBondContact O-N 3.38Å; Q478-I481 WeakPolarHBondContact O-CB 3.5Å; Q478-I481 PolarHBondContact O-N 3.23Å; Q478-I481 VanDerWaalsContact O-N 3.14Å; Q478-D482 PolarHBondContact NE2-OD1 2.96Å; Q478-D482 VanDerWaalsContact O-CG 3.23Å; Q478-D482 PolarHBondContact O-N 2.91Å
479E80.9Confident67.6Low151 Ų151106.1 Ų106.171%0.70654%0.537SS*.Hα-helixtrans-59.5-34.3177-170.9178.8177.600113.5S477 R483S477-E479 PolarHBondContact O-N 3.11Å; E479-R483 WeakPolarHBondContact O-CB 3.3Å; E479-R483 PolarHBondContact O-N 3.32Å
480N81.7Confident70Confident40 Ų40104.4 Ų104.421%0.21452%0.522CS..Hα-helixtrans-76.7-33.5178.6-75.2-23.9000111.6S477 Q478 L484 L498 V505S477-N480 WeakPolarHBondContact O-CB 3.2Å; S477-N480 PolarHBondContact O-N 3.13Å; S477-N480 PolarHBondContact OG-ND2 2.95Å; Q478-N480 VanDerWaalsContact C-N 3.27Å; Q478-N480 PolarHBondContact O-N 3.38Å; N480-L484 PolarHBondContact O-N 2.73Å; N480-L498 HydrophobicContact CB-CD1 3.86Å; N480-L498 HydrophobicContact CB-CD2 4.41Å; N480-V505 HydrophobicContact CB-CG2 3.64Å; N480-V505 VanDerWaalsContact CG-CG2 3.46Å; N480-V505 VanDerWaalsContact OD1-CG2 3.31Å; N480-V505 WeakPolarHBondContact OD1-CG2 3.18Å
481I82.4Confident72.2Confident9 Ų999.9 Ų99.95%0.04651%0.505CS..Hα-helixtrans-66-49.6173.9-56.2172.8000108.8P476 S477 Q478 R483 L484 V485 A494 E495 L498P476-I481 HydrophobicContact CB-CG1 4.44Å; P476-I481 HydrophobicContact CG-CD1 4.21Å; P476-I481 HydrophobicContact CG-CG1 4.48Å; S477-I481 PolarHBondContact O-N 3.45Å; Q478-I481 WeakPolarHBondContact O-CB 3.5Å; Q478-I481 PolarHBondContact O-N 3.23Å; Q478-I481 VanDerWaalsContact O-N 3.14Å; I481-R483 PolarHBondContact O-N 3.4Å; I481-L484 PolarHBondContact O-N 3.14Å; I481-L484 VanDerWaalsContact O-N 3.07Å; I481-V485 HydrophobicContact CG2-CG2 4.28Å; I481-V485 WeakPolarHBondContact O-CG2 3.49Å; I481-V485 PolarHBondContact O-N 3.49Å; I481-A494 HydrophobicContact CG2-CB 4.36Å; I481-E495 HydrophobicContact CD1-CB 4.19Å; I481-E495 HydrophobicContact CD1-CG 3.88Å; I481-L498 HydrophobicContact CB-CD1 4.43Å; I481-L498 HydrophobicContact CG1-CD1 3.84Å
482D82.7Confident74.1Confident86 Ų8698.7 Ų98.746%0.4650%0.498SS..Hα-helixtrans-59.3-33.4-179.8-64.5-15.4000111.9Q478 V485 Y486Q478-D482 PolarHBondContact NE2-OD1 2.96Å; Q478-D482 VanDerWaalsContact O-CG 3.23Å; Q478-D482 PolarHBondContact O-N 2.91Å; D482-V485 PolarHBondContact O-N 3.16Å; D482-Y486 WeakPolarHBondContact O-CB 3.44Å; D482-Y486 PolarHBondContact O-N 3.3Å
483R81.9Confident76.3Confident160 Ų16090 Ų9060%0.60447%0.469SS*.Hα-helixtrans-68.5-37.7177.1-159.5165.9-172166.82.2113.1E479 I481 M487 V505E479-R483 WeakPolarHBondContact O-CB 3.3Å; E479-R483 PolarHBondContact O-N 3.32Å; I481-R483 PolarHBondContact O-N 3.4Å; R483-M487 VanDerWaalsContact O-CG 3.31Å; R483-M487 WeakPolarHBondContact O-CG 3.36Å; R483-M487 PolarHBondContact O-N 3.14Å; R483-V505 HydrophobicContact CG-CG1 4.44Å
484L81Confident78Confident0 Ų080.6 Ų80.60%043%0.425CS..Hα-helixtrans-74.5-35.2173.3-70.7179.2000111.8N480 I481 Y486 M487 G488 F489 A494 L498 V505 A508 A509N480-L484 PolarHBondContact O-N 2.73Å; I481-L484 PolarHBondContact O-N 3.14Å; I481-L484 VanDerWaalsContact O-N 3.07Å; L484-Y486 VanDerWaalsContact C-N 3.33Å; L484-M487 HydrophobicContact CD2-SD 4.24Å; L484-M487 WeakPolarHBondContact O-CB 3.29Å; L484-M487 PolarHBondContact O-N 3.02Å; L484-M487 VanDerWaalsContact O-N 3.12Å; L484-G488 PolarHBondContact O-N 3.47Å; L484-F489 HydrophobicContact CB-CD2 4.37Å; L484-F489 HydrophobicContact CD2-CD2 4.27Å; L484-F489 WeakPolarHBondContact O-CD2 3.42Å; L484-F489 PolarHBondContact O-N 3.07Å; L484-A494 HydrophobicContact CB-CB 3.63Å; L484-A494 HydrophobicContact CD1-CB 3.9Å; L484-A494 HydrophobicContact CG-CB 4.43Å; L484-L498 HydrophobicContact CD1-CD1 3.76Å; L484-L498 HydrophobicContact CD1-CD2 3.89Å; L484-L498 HydrophobicContact CD1-CG 3.6Å; L484-V505 HydrophobicContact CD2-CG1 3.91Å; L484-V505 HydrophobicContact CG-CG1 4.15Å; L484-A508 HydrophobicContact CD1-CB 3.92Å; L484-A509 HydrophobicContact CD2-CB 3.59Å
485V86.1Confident79.7Confident59 Ų5975.5 Ų75.536%0.35840%0.401SS..Hα-helixtrans-63.4-41.7173.3173.70000111I481 D482 M487 G488 F489 A491I481-V485 HydrophobicContact CG2-CG2 4.28Å; I481-V485 WeakPolarHBondContact O-CG2 3.49Å; I481-V485 PolarHBondContact O-N 3.49Å; D482-V485 PolarHBondContact O-N 3.16Å; V485-M487 PolarHBondContact O-N 3.38Å; V485-G488 WeakPolarHBondContact O-CA 3.45Å; V485-G488 PolarHBondContact O-N 3.49Å; V485-F489 WeakPolarHBondContact CA-O 2.95Å; V485-A491 HydrophobicContact CG2-CB 3.76Å
486Y85.6Confident80.7Confident209 Ų20972.8 Ų72.882%0.8238%0.384SS*.Hα-helixtrans-61-31173.4-174.9-96.2000112.7D482 L484 G488D482-Y486 WeakPolarHBondContact O-CB 3.44Å; D482-Y486 PolarHBondContact O-N 3.3Å; L484-Y486 VanDerWaalsContact C-N 3.33Å; Y486-G488 PolarHBondContact O-N 3.26Å
487M79.8Confident81.2Confident116 Ų11672 Ų7257%0.57138%0.379SS*.THydrogen-bonded Turntrans-75.7-1.5174-67.2174.5118.400113.5R483 L484 V485 F489 A509R483-M487 VanDerWaalsContact O-CG 3.31Å; R483-M487 WeakPolarHBondContact O-CG 3.36Å; R483-M487 PolarHBondContact O-N 3.14Å; L484-M487 HydrophobicContact CD2-SD 4.24Å; L484-M487 WeakPolarHBondContact O-CB 3.29Å; L484-M487 PolarHBondContact O-N 3.02Å; L484-M487 VanDerWaalsContact O-N 3.12Å; V485-M487 PolarHBondContact O-N 3.38Å; M487-F489 HydrophobicContact CB-CD2 3.95Å; M487-F489 HydrophobicContact CB-CE2 3.91Å; M487-A509 HydrophobicContact CE-CB 4.47Å; M487-A509 HydrophobicContact SD-CB 4.04Å
488G80.3Confident81.4Confident68 Ų6869.1 Ų69.170%0.70136%0.359SS*.THydrogen-bonded Turntrans96.410.8175.200000114.9L484 V485 Y486L484-G488 PolarHBondContact O-N 3.47Å; V485-G488 WeakPolarHBondContact O-CA 3.45Å; V485-G488 PolarHBondContact O-N 3.49Å; Y486-G488 PolarHBondContact O-N 3.26Å
489F83.4Confident81.5Confident32 Ų3270.7 Ų70.714%0.1436%0.36CS..  trans-88.1148.6175.8-58.3-66.9000111.7L484 V485 M487 A509 L512 A513L484-F489 HydrophobicContact CB-CD2 4.37Å; L484-F489 HydrophobicContact CD2-CD2 4.27Å; L484-F489 WeakPolarHBondContact O-CD2 3.42Å; L484-F489 PolarHBondContact O-N 3.07Å; V485-F489 WeakPolarHBondContact CA-O 2.95Å; M487-F489 HydrophobicContact CB-CD2 3.95Å; M487-F489 HydrophobicContact CB-CE2 3.91Å; F489-A509 HydrophobicContact CE2-CB 4.41Å; F489-L512 HydrophobicContact CB-CD1 4.27Å; F489-L512 HydrophobicContact CD1-CB 3.73Å; F489-L512 HydrophobicContact CD1-CD1 4.21Å; F489-L512 HydrophobicContact CD2-CD1 4.34Å; F489-L512 HydrophobicContact CE1-CB 3.51Å; F489-L512 HydrophobicContact CE2-CB 4.36Å; F489-L512 HydrophobicContact CG-CB 4.26Å; F489-L512 HydrophobicContact CG-CD1 4.01Å; F489-L512 HydrophobicContact CZ-CB 3.85Å; F489-A513 HydrophobicContact CZ-CB 4.08Å
490D85.3Confident81.3Confident96 Ų9666.6 Ų66.651%0.51335%0.345SS..  trans-65.4140.5176.1-176.4-90.4000111.2L492 V493 A494D490-L492 VanDerWaalsContact C-N 3.29Å; D490-L492 PolarHBondContact O-N 2.85Å; D490-L492 WeakPolarHBondContact OD1-CB 3.48Å; D490-L492 PolarHBondContact OD1-N 3.18Å; D490-V493 HydrophobicContact CB-CB 4.36Å; D490-V493 HydrophobicContact CB-CG2 4.07Å; D490-V493 PolarHBondContact O-N 3.11Å; D490-V493 VanDerWaalsContact O-N 3.17Å; D490-A494 WeakPolarHBondContact O-CB 3.45Å; D490-A494 PolarHBondContact O-N 2.85Å
491A81.6Confident81.1Confident46 Ų4667.2 Ų67.238%0.3835%0.346SS..Hα-helixtrans-60.4-36.8-174.100000113V485 E495V485-A491 HydrophobicContact CG2-CB 3.76Å; A491-E495 WeakPolarHBondContact O-CB 3.23Å; A491-E495 PolarHBondContact O-N 3.2Å
492L79.4Confident80.6Confident129 Ų12978 Ų7868%0.67539%0.386SS*.Hα-helixtrans-72.7-36.2-180-62.1173.5000111.2D490 A496D490-L492 VanDerWaalsContact C-N 3.29Å; D490-L492 PolarHBondContact O-N 2.85Å; D490-L492 WeakPolarHBondContact OD1-CB 3.48Å; D490-L492 PolarHBondContact OD1-N 3.18Å; L492-A496 WeakPolarHBondContact O-CB 3.44Å; L492-A496 PolarHBondContact O-N 2.9Å
493V82.5Confident80.1Confident37 Ų3775.2 Ų75.222%0.22438%0.377CS..Hα-helixtrans-74.6-38177.8-174.40000111.1D490 A496 A497 L512 G517 L519D490-V493 HydrophobicContact CB-CB 4.36Å; D490-V493 HydrophobicContact CB-CG2 4.07Å; D490-V493 PolarHBondContact O-N 3.11Å; D490-V493 VanDerWaalsContact O-N 3.17Å; V493-A496 PolarHBondContact O-N 3.4Å; V493-A497 VanDerWaalsContact O-CB 3.26Å; V493-A497 WeakPolarHBondContact O-CB 3.36Å; V493-A497 PolarHBondContact O-N 3.15Å; V493-L512 HydrophobicContact CG1-CD2 3.5Å; V493-L512 VanDerWaalsContact CG1-CD2 3.5Å; V493-G517 WeakPolarHBondContact CG1-O 3.49Å; V493-L519 HydrophobicContact CG1-CD1 4.47Å; V493-L519 HydrophobicContact CG1-CG 4.25Å
494A82.7Confident79.9Confident0 Ų071 Ų710%037%0.366CS..Hα-helixtrans-61.3-44.7173.200000111.6I481 L484 D490 A497 L498I481-A494 HydrophobicContact CG2-CB 4.36Å; L484-A494 HydrophobicContact CB-CB 3.63Å; L484-A494 HydrophobicContact CD1-CB 3.9Å; L484-A494 HydrophobicContact CG-CB 4.43Å; D490-A494 WeakPolarHBondContact O-CB 3.45Å; D490-A494 PolarHBondContact O-N 2.85Å; A494-A497 PolarHBondContact O-N 3.5Å; A494-L498 WeakPolarHBondContact O-CB 3.49Å; A494-L498 VanDerWaalsContact O-CG 3.24Å; A494-L498 WeakPolarHBondContact O-CG 3.42Å; A494-L498 PolarHBondContact O-N 2.72Å
495E81.4Confident79.9Confident57 Ų5772.2 Ų72.227%0.26637%0.374SS..Hα-helixtrans-63-46.7176.3-167.7-170.7164.100111.5P476 I481 A491 A497 L498 R499P476-E495 HydrophobicContact CG-CG 3.65Å; I481-E495 HydrophobicContact CD1-CB 4.19Å; I481-E495 HydrophobicContact CD1-CG 3.88Å; A491-E495 WeakPolarHBondContact O-CB 3.23Å; A491-E495 PolarHBondContact O-N 3.2Å; E495-A497 VanDerWaalsContact C-N 3.34Å; E495-A497 PolarHBondContact O-N 3.48Å; E495-L498 PolarHBondContact O-N 3.35Å; E495-R499 WeakPolarHBondContact O-CB 3.28Å; E495-R499 PolarHBondContact O-N 2.88Å; E495-R499 IonicContact OE1-CZ 3.48Å; E495-R499 IonicContact OE1-NH2 2.79Å; E495-R499 PolarHBondContact OE1-NH2 3.26Å
496A77Confident79.5Confident35 Ų3576 Ų7629%0.28939%0.388SS..Hα-helixtrans-61.8-41.5177.100000111.9L492 V493 R499 V500 L519L492-A496 WeakPolarHBondContact O-CB 3.44Å; L492-A496 PolarHBondContact O-N 2.9Å; V493-A496 PolarHBondContact O-N 3.4Å; A496-R499 PolarHBondContact O-N 3.33Å; A496-V500 WeakPolarHBondContact O-CG2 3.37Å; A496-V500 PolarHBondContact O-N 2.9Å; A496-L519 HydrophobicContact CB-CD1 3.55Å
497A77.3Confident79.1Confident0 Ų070 Ų700%037%0.369CS..Hα-helixtrans-65.2-44.5177.900000111.2V493 A494 E495 R499 V500 F501 A508 L512 L519V493-A497 VanDerWaalsContact O-CB 3.26Å; V493-A497 WeakPolarHBondContact O-CB 3.36Å; V493-A497 PolarHBondContact O-N 3.15Å; A494-A497 PolarHBondContact O-N 3.5Å; E495-A497 VanDerWaalsContact C-N 3.34Å; E495-A497 PolarHBondContact O-N 3.48Å; A497-R499 VanDerWaalsContact C-N 3.27Å; A497-R499 PolarHBondContact O-N 3.49Å; A497-V500 PolarHBondContact O-N 3.13Å; A497-F501 WeakPolarHBondContact O-CD2 3.3Å; A497-F501 PolarHBondContact O-N 3.47Å; A497-A508 HydrophobicContact CB-CB 4.03Å; A497-L512 HydrophobicContact CB-CD1 3.76Å; A497-L512 HydrophobicContact CB-CD2 4.22Å; A497-L512 HydrophobicContact CB-CG 4.05Å; A497-L519 HydrophobicContact CB-CD1 4.33Å; A497-L519 HydrophobicContact CB-CD2 3.81Å; A497-L519 HydrophobicContact CB-CG 4.4Å
498L79.8Confident79.2Confident1 Ų164.4 Ų64.41%0.00534%0.342CS..Hα-helixtrans-65.9-30.7176.8-71.6169.5000112.4P476 N480 I481 L484 A494 E495 F501 R502 G503 V505 A508P476-L498 HydrophobicContact CB-CB 3.67Å; P476-L498 HydrophobicContact CB-CD1 4.29Å; P476-L498 HydrophobicContact CG-CB 4.23Å; N480-L498 HydrophobicContact CB-CD1 3.86Å; N480-L498 HydrophobicContact CB-CD2 4.41Å; I481-L498 HydrophobicContact CB-CD1 4.43Å; I481-L498 HydrophobicContact CG1-CD1 3.84Å; L484-L498 HydrophobicContact CD1-CD1 3.76Å; L484-L498 HydrophobicContact CD1-CD2 3.89Å; L484-L498 HydrophobicContact CD1-CG 3.6Å; A494-L498 WeakPolarHBondContact O-CB 3.49Å; A494-L498 VanDerWaalsContact O-CG 3.24Å; A494-L498 WeakPolarHBondContact O-CG 3.42Å; A494-L498 PolarHBondContact O-N 2.72Å; E495-L498 PolarHBondContact O-N 3.35Å; L498-F501 CarbonylContact O-C 3.59Å; L498-R502 CarbonylContact O-C 3.54Å; L498-R502 WeakPolarHBondContact O-CA 3.42Å; L498-R502 PolarHBondContact O-N 3.42Å; L498-G503 PolarHBondContact O-N 3.06Å; L498-V505 HydrophobicContact CD2-CG2 4.03Å; L498-A508 HydrophobicContact CD2-CB 4.03Å; L498-A508 HydrophobicContact CG-CB 4.48Å
499R78.7Confident79.2Confident153 Ų15361.8 Ų61.858%0.57731%0.313SS*.Hα-helixtrans-68.5-40.3173.5-163178.2-66.5158.3-0.4111.7E495 A496 A497E495-R499 WeakPolarHBondContact O-CB 3.28Å; E495-R499 PolarHBondContact O-N 2.88Å; E495-R499 IonicContact OE1-CZ 3.48Å; E495-R499 IonicContact OE1-NH2 2.79Å; E495-R499 PolarHBondContact OE1-NH2 3.26Å; A496-R499 PolarHBondContact O-N 3.33Å; A497-R499 VanDerWaalsContact C-N 3.27Å; A497-R499 PolarHBondContact O-N 3.49Å
500V77.3Confident79Confident65 Ų6565.6 Ų65.639%0.39433%0.332SS..Hα-helixtrans-66.5-45.1174.3171.80000111.3A496 A497 R502 L523A496-V500 WeakPolarHBondContact O-CG2 3.37Å; A496-V500 PolarHBondContact O-N 2.9Å; A497-V500 PolarHBondContact O-N 3.13Å; V500-R502 VanDerWaalsContact C-N 3.32Å; V500-R502 PolarHBondContact O-N 2.99Å; V500-L523 HydrophobicContact CG1-CD1 4.03Å; V500-L523 HydrophobicContact CG1-CD2 4.31Å
501F77.3Confident78.6Confident53 Ų5362.7 Ų62.723%0.23232%0.317CS..THydrogen-bonded Turntrans-9316.5-176.7-62.1-66.2000113.8A497 L498 G503 N504 L507 A508 T511A497-F501 WeakPolarHBondContact O-CD2 3.3Å; A497-F501 PolarHBondContact O-N 3.47Å; L498-F501 CarbonylContact O-C 3.59Å; F501-G503 VanDerWaalsContact C-N 3.32Å; F501-G503 PolarHBondContact O-N 3.44Å; F501-N504 HydrophobicContact CB-CB 4.46Å; F501-N504 WeakPolarHBondContact O-CB 3.33Å; F501-N504 PolarHBondContact O-N 3.17Å; F501-L507 HydrophobicContact CD1-CB 4.29Å; F501-L507 HydrophobicContact CG-CB 4.39Å; F501-A508 HydrophobicContact CD2-CB 3.94Å; F501-T511 HydrophobicContact CE2-CG2 4.16Å; F501-T511 HydrophobicContact CZ-CG2 3.96Å
502R71.8Confident78.7Confident237 Ų23760.5 Ų60.589%0.89430%0.299SS*.THydrogen-bonded Turntrans4649.6175.8-58.7-174.6-179.3-169.6-0.9113.6L498 V500 N504L498-R502 CarbonylContact O-C 3.54Å; L498-R502 WeakPolarHBondContact O-CA 3.42Å; L498-R502 PolarHBondContact O-N 3.42Å; V500-R502 VanDerWaalsContact C-N 3.32Å; V500-R502 PolarHBondContact O-N 2.99Å; R502-N504 PolarHBondContact O-N 3.23Å
503G71.3Confident78.7Confident26 Ų2657.5 Ų57.527%0.26829%0.293SS..THydrogen-bonded Turntrans82.71.9176.800000115.8L498 F501 V505L498-G503 PolarHBondContact O-N 3.06Å; F501-G503 VanDerWaalsContact C-N 3.32Å; F501-G503 PolarHBondContact O-N 3.44Å; G503-V505 PolarHBondContact O-N 3.01Å; G503-V505 VanDerWaalsContact O-N 3.08Å
504N77.9Confident78.5Confident72 Ų7263.6 Ų63.639%0.38532%0.318SS..  trans-78.794.3177.3-167.6-36.8000111.8F501 R502 Q506 L507 A508F501-N504 HydrophobicContact CB-CB 4.46Å; F501-N504 WeakPolarHBondContact O-CB 3.33Å; F501-N504 PolarHBondContact O-N 3.17Å; R502-N504 PolarHBondContact O-N 3.23Å; N504-Q506 PolarHBondContact O-N 3.14Å; N504-Q506 PolarHBondContact OD1-N 2.9Å; N504-L507 HydrophobicContact CB-CB 4.39Å; N504-L507 HydrophobicContact CB-CD1 4.33Å; N504-L507 WeakPolarHBondContact ND2-CD1 3.46Å; N504-L507 PolarHBondContact O-N 3.23Å; N504-L507 PolarHBondContact OD1-N 3.14Å; N504-L507 VanDerWaalsContact OD1-N 3.16Å; N504-A508 WeakPolarHBondContact O-CB 3.37Å; N504-A508 PolarHBondContact O-N 3.47Å
505V81.9Confident78.2Confident25 Ų2566.7 Ų66.715%0.15234%0.335CS..Hα-helixtrans-56.5-36.7-179.3-179.20000112.6N480 R483 L484 L498 G503 A509N480-V505 HydrophobicContact CB-CG2 3.64Å; N480-V505 VanDerWaalsContact CG-CG2 3.46Å; N480-V505 VanDerWaalsContact OD1-CG2 3.31Å; N480-V505 WeakPolarHBondContact OD1-CG2 3.18Å; R483-V505 HydrophobicContact CG-CG1 4.44Å; L484-V505 HydrophobicContact CD2-CG1 3.91Å; L484-V505 HydrophobicContact CG-CG1 4.15Å; L498-V505 HydrophobicContact CD2-CG2 4.03Å; G503-V505 PolarHBondContact O-N 3.01Å; G503-V505 VanDerWaalsContact O-N 3.08Å; V505-A509 VanDerWaalsContact O-CB 3.26Å; V505-A509 WeakPolarHBondContact O-CB 3.45Å; V505-A509 PolarHBondContact O-N 3.3Å
506Q77.2Confident77.8Confident140 Ų14067.4 Ų67.465%0.65436%0.358SS*.Hα-helixtrans-74.8-41.5-172.7-167.6156.8-8.400112.1N504 Q510N504-Q506 PolarHBondContact O-N 3.14Å; N504-Q506 PolarHBondContact OD1-N 2.9Å; Q506-Q510 WeakPolarHBondContact O-CB 3.34Å; Q506-Q510 VanDerWaalsContact O-CG 3.26Å; Q506-Q510 WeakPolarHBondContact O-CG 3.38Å; Q506-Q510 PolarHBondContact O-N 3.12Å; Q506-Q510 VanDerWaalsContact O-N 3.13Å
507L78.3Confident77.5Confident81 Ų8166.9 Ų66.942%0.42436%0.356SS..Hα-helixtrans-67.5-43.4172.8-71.5173.4000111.1F501 N504 A509 Q510 T511F501-L507 HydrophobicContact CD1-CB 4.29Å; F501-L507 HydrophobicContact CG-CB 4.39Å; N504-L507 HydrophobicContact CB-CB 4.39Å; N504-L507 HydrophobicContact CB-CD1 4.33Å; N504-L507 WeakPolarHBondContact ND2-CD1 3.46Å; N504-L507 PolarHBondContact O-N 3.23Å; N504-L507 PolarHBondContact OD1-N 3.14Å; N504-L507 VanDerWaalsContact OD1-N 3.16Å; L507-A509 PolarHBondContact O-N 2.9Å; L507-Q510 PolarHBondContact O-N 3.29Å; L507-T511 PolarHBondContact O-N 2.87Å; L507-T511 PolarHBondContact O-OG1 3.04Å; L507-T511 VanDerWaalsContact O-OG1 3.1Å
508A80.6Confident77.3Confident0 Ų070.4 Ų70.40%038%0.38CS..Hα-helixtrans-59.3-46.7177.100000112.2L484 A497 L498 F501 N504 Q510 T511 L512L484-A508 HydrophobicContact CD1-CB 3.92Å; A497-A508 HydrophobicContact CB-CB 4.03Å; L498-A508 HydrophobicContact CD2-CB 4.03Å; L498-A508 HydrophobicContact CG-CB 4.48Å; F501-A508 HydrophobicContact CD2-CB 3.94Å; N504-A508 WeakPolarHBondContact O-CB 3.37Å; N504-A508 PolarHBondContact O-N 3.47Å; A508-Q510 PolarHBondContact O-N 2.98Å; A508-T511 PolarHBondContact O-N 3.48Å; A508-L512 WeakPolarHBondContact O-CB 3.36Å; A508-L512 VanDerWaalsContact O-CG 3.23Å; A508-L512 WeakPolarHBondContact O-CG 3.38Å; A508-L512 PolarHBondContact O-N 2.9Å
509A80.3Confident76.8Confident12 Ų1272.8 Ų72.810%0.09939%0.393CS..Hα-helixtrans-62.6-42.2177.500000112.4L484 M487 F489 V505 L507 A513L484-A509 HydrophobicContact CD2-CB 3.59Å; M487-A509 HydrophobicContact CE-CB 4.47Å; M487-A509 HydrophobicContact SD-CB 4.04Å; F489-A509 HydrophobicContact CE2-CB 4.41Å; V505-A509 VanDerWaalsContact O-CB 3.26Å; V505-A509 WeakPolarHBondContact O-CB 3.45Å; V505-A509 PolarHBondContact O-N 3.3Å; L507-A509 PolarHBondContact O-N 2.9Å; A509-A513 WeakPolarHBondContact O-CB 3.37Å; A509-A513 PolarHBondContact O-N 3.16Å
510Q79.6Confident76.3Confident113 Ų11367.3 Ų67.353%0.52838%0.377SS..Hα-helixtrans-65.8-44.1179.6-75.9175.82.800111.8Q506 L507 A508 H514Q506-Q510 WeakPolarHBondContact O-CB 3.34Å; Q506-Q510 VanDerWaalsContact O-CG 3.26Å; Q506-Q510 WeakPolarHBondContact O-CG 3.38Å; Q506-Q510 PolarHBondContact O-N 3.12Å; Q506-Q510 VanDerWaalsContact O-N 3.13Å; L507-Q510 PolarHBondContact O-N 3.29Å; A508-Q510 PolarHBondContact O-N 2.98Å; Q510-H514 WeakPolarHBondContact O-CB 3.39Å; Q510-H514 PolarHBondContact O-N 3.02Å
511T77.6Confident75Confident35 Ų3570.6 Ų70.622%0.21540%0.4CS..Hα-helixtrans-68.3-38.5178.2-55.60000111.9F501 L507 A508 N515F501-T511 HydrophobicContact CE2-CG2 4.16Å; F501-T511 HydrophobicContact CZ-CG2 3.96Å; L507-T511 PolarHBondContact O-N 2.87Å; L507-T511 PolarHBondContact O-OG1 3.04Å; L507-T511 VanDerWaalsContact O-OG1 3.1Å; A508-T511 PolarHBondContact O-N 3.48Å; T511-N515 WeakPolarHBondContact CG2-ND2 3.34Å; T511-N515 WeakPolarHBondContact O-CB 3.36Å; T511-N515 PolarHBondContact O-N 3.01Å; T511-N515 VanDerWaalsContact O-N 3.14Å; T511-N515 PolarHBondContact O-ND2 3.4Å
512L82Confident73.6Confident0 Ų076.9 Ų76.90%043%0.43CS..Hα-helixtrans-69.6-40.8175.9-70175.7000112.2F489 V493 A497 A508 H514 N515 G516 G517 L519F489-L512 HydrophobicContact CB-CD1 4.27Å; F489-L512 HydrophobicContact CD1-CB 3.73Å; F489-L512 HydrophobicContact CD1-CD1 4.21Å; F489-L512 HydrophobicContact CD2-CD1 4.34Å; F489-L512 HydrophobicContact CE1-CB 3.51Å; F489-L512 HydrophobicContact CE2-CB 4.36Å; F489-L512 HydrophobicContact CG-CB 4.26Å; F489-L512 HydrophobicContact CG-CD1 4.01Å; F489-L512 HydrophobicContact CZ-CB 3.85Å; V493-L512 HydrophobicContact CG1-CD2 3.5Å; V493-L512 VanDerWaalsContact CG1-CD2 3.5Å; A497-L512 HydrophobicContact CB-CD1 3.76Å; A497-L512 HydrophobicContact CB-CD2 4.22Å; A497-L512 HydrophobicContact CB-CG 4.05Å; A508-L512 WeakPolarHBondContact O-CB 3.36Å; A508-L512 VanDerWaalsContact O-CG 3.23Å; A508-L512 WeakPolarHBondContact O-CG 3.38Å; A508-L512 PolarHBondContact O-N 2.9Å; L512-H514 VanDerWaalsContact C-N 3.32Å; L512-H514 PolarHBondContact O-N 3.44Å; L512-N515 CarbonylContact O-C 3.52Å; L512-N515 PolarHBondContact O-N 3.14Å; L512-G516 PolarHBondContact O-N 3.43Å; L512-G517 PolarHBondContact O-N 3.25Å; L512-L519 HydrophobicContact CD2-CD2 4.05Å; L512-L519 HydrophobicContact CD2-CG 4.07Å
513A80.8Confident72.7Confident66 Ų6668.7 Ų68.755%0.54540%0.404SS..Hα-helixtrans-62.2-40.8175.400000111.8F489 A509 N515F489-A513 HydrophobicContact CZ-CB 4.08Å; A509-A513 WeakPolarHBondContact O-CB 3.37Å; A509-A513 PolarHBondContact O-N 3.16Å; A513-N515 VanDerWaalsContact C-N 3.34Å
514H78.7Confident71.3Confident164 Ų16473.2 Ų73.276%0.75943%0.428SS*.Hα-helixtrans-68.8-33.3-179.8-164.469.3000112.7Q510 L512Q510-H514 WeakPolarHBondContact O-CB 3.39Å; Q510-H514 PolarHBondContact O-N 3.02Å; L512-H514 VanDerWaalsContact C-N 3.32Å; L512-H514 PolarHBondContact O-N 3.44Å
515N74.8Confident69.3Low65 Ų6577.7 Ų77.735%0.34845%0.451SS..THydrogen-bonded Turntrans-101.524.1-177.4-64.3-52.6000113.4T511 L512 A513 G517 S518T511-N515 WeakPolarHBondContact CG2-ND2 3.34Å; T511-N515 WeakPolarHBondContact O-CB 3.36Å; T511-N515 PolarHBondContact O-N 3.01Å; T511-N515 VanDerWaalsContact O-N 3.14Å; T511-N515 PolarHBondContact O-ND2 3.4Å; L512-N515 CarbonylContact O-C 3.52Å; L512-N515 PolarHBondContact O-N 3.14Å; A513-N515 VanDerWaalsContact C-N 3.34Å; N515-G517 VanDerWaalsContact C-N 3.3Å; N515-G517 PolarHBondContact O-N 3.48Å; N515-S518 WeakPolarHBondContact CB-O 3.37Å; N515-S518 PolarHBondContact O-N 3.46Å
516G74.4Confident67Low72 Ų7281.9 Ų81.974%0.74248%0.482SS*.THydrogen-bonded Turntrans62.631.1173.700000114.8L512L512-G516 PolarHBondContact O-N 3.43Å
517G69.9Low65.1Low24 Ų2481.1 Ų81.125%0.24749%0.489CS..THydrogen-bonded Turntrans84.513.3179.300000114.9V493 L512 N515V493-G517 WeakPolarHBondContact CG1-O 3.49Å; L512-G517 PolarHBondContact O-N 3.25Å; N515-G517 VanDerWaalsContact C-N 3.3Å; N515-G517 PolarHBondContact O-N 3.48Å
518S73.2Confident62.8Low74 Ų7485.3 Ų85.352%0.51751%0.506SS..SBendtrans-121151.6177.6-53.40000111.1N515N515-S518 WeakPolarHBondContact CB-O 3.37Å; N515-S518 PolarHBondContact O-N 3.46Å
519L70Confident60.4Low51 Ų5192.1 Ų92.127%0.26754%0.543SS..  trans-82.7139.8172.6-75.1164.9000110.6V493 A496 A497 L512V493-L519 HydrophobicContact CG1-CD1 4.47Å; V493-L519 HydrophobicContact CG1-CG 4.25Å; A496-L519 HydrophobicContact CB-CD1 3.55Å; A497-L519 HydrophobicContact CB-CD1 4.33Å; A497-L519 HydrophobicContact CB-CD2 3.81Å; A497-L519 HydrophobicContact CB-CG 4.4Å; L512-L519 HydrophobicContact CD2-CD2 4.05Å; L512-L519 HydrophobicContact CD2-CG 4.07Å
520P66.9Low57.9Low39 Ų3997.7 Ų97.725%0.25358%0.581SS.*  trans-65.3140.7178.920-26.2000111.7E522 L523P520-E522 PolarHBondContact O-N 2.99Å; P520-E522 VanDerWaalsContact O-N 3.1Å; P520-L523 HydrophobicContact CG-CD1 3.9Å
521P51.5Low55.6Low134 Ų134100.4 Ų100.487%0.8760%0.598SS**THydrogen-bonded Turntrans-66.7-10-174.6-19.932000115.8
522E47.5Very low53.3Low185 Ų185103.9 Ų103.986%0.86462%0.624SS**THydrogen-bonded Turntrans-91.55.5-171.2-67174.9165.700113.9P520P520-E522 PolarHBondContact O-N 2.99Å; P520-E522 VanDerWaalsContact O-N 3.1Å
523L51.7Low51.4Low65 Ų65109.6 Ų109.634%0.3466%0.661SS.*SBendtrans-90.3129.8176.6-69.1163.5000110.2V500 P520 L525V500-L523 HydrophobicContact CG1-CD1 4.03Å; V500-L523 HydrophobicContact CG1-CD2 4.31Å; P520-L523 HydrophobicContact CG-CD1 3.9Å; L523-L525 PolarHBondContact O-N 2.86Å
524P43.2Very low49Very low121 Ų121112.5 Ų112.579%0.78667%0.674SS**  trans-67.9106.4-17325.4-31.1000110.7S526P524-S526 PolarHBondContact O-N 2.98Å
525L35.5Very low46.8Very low165 Ų165109.2 Ų109.286%0.86468%0.676SS**  trans-77.9105.7158.1-71.8163.4000106.8L523 P527L523-L525 PolarHBondContact O-N 2.86Å; L525-P527 WeakPolarHBondContact O-CD 3.49Å
526S33.5Very low44.5Very low114 Ų114112.9 Ų112.980%0.79770%0.701SS**  trans-69.8139.5169.8-60.60000110.6P524P524-S526 PolarHBondContact O-N 2.98Å
527P36.8Very low42.4Very low124 Ų124114.8 Ų114.881%0.80570%0.703SS**  trans-119.3150.8140.219.7-0.6000111.3L525L525-P527 WeakPolarHBondContact O-CD 3.49Å
528E30.8Very low40.8Very low168 Ų168119.9 Ų119.979%0.78573%0.732SS**  trans-78.5164.5-171.1-60.6-163.2145.500115.3
529D29.6Very low38.6Very low144 Ų144121.6 Ų121.677%0.7774%0.744SS**  trans63.4113.2151.1-75.3-12.2000121.6
530S27.1Very low36.8Very low129 Ų129126.6 Ų126.690%0.90277%0.771SS**  trans-161.1121.6135.9-76.80000111.7
531L32.5Very low35.2Very low169 Ų169130.6 Ų130.689%0.88580%0.799SS**  trans-64.5139.4175-73.5141.2000113.5
532S29.1Very low34.6Very low109 Ų109129.3 Ų129.376%0.76280%0.8SS**  146.5142.6124.5-62.20000113.4
533P41.7Very low34.2Very low120 Ų120123.6 Ų123.678%0.77979%0.791SS**  trans-89.6166.1177.337.1-32.4000111.9
534P30.5Very low33.3Very low126 Ų126126 Ų12682%0.81881%0.809SS**  -133143.5129.431.1-17000113.3
535A32.6Very low33Very low95 Ų95125.9 Ų125.979%0.78581%0.81SS**  trans-67.9140168.300000111.3
536T27.1Very low33.3Very low143 Ų143122.1 Ų122.188%0.87780%0.798SS**  trans-139.8124.4151.538.30000109.5
537S29.3Very low33.7Very low112 Ų112118.8 Ų118.878%0.78378%0.777SS**  trans-65.4164.5176.9-49.50000112.3
538P36.6Very low34.3Very low131 Ų131116 Ų11685%0.85176%0.761SS**  trans-83145.8-171.134.4-30.9000111.1
539S27.4Very low35.6Very low110 Ų110111.8 Ų111.877%0.76975%0.746SS**  trans-134.6110.4165.7-150.80000109.7
540D32.6Very low37Very low156 Ų156109.4 Ų109.483%0.83473%0.734SS**  trans30.397.9150.7-63.1-32.2000118.3
541S31.9Very low38.8Very low123 Ų123109.4 Ų109.486%0.8672%0.72SS**  trans-104.696.1149-53.40000108
542A39.3Very low40.5Very low107 Ų107106.3 Ų106.388%0.88470%0.704SS**  trans-61.4132.216400000109.7
543G38.7Very low42.4Very low65 Ų65105.7 Ų105.767%0.6769%0.69SS**  trans122.277.2160.700000115
544T34.8Very low44.1Very low116 Ų116104.2 Ų104.271%0.71267%0.673SS**  trans-166.555.8147.138.60000109.9S546T544-S546 PolarHBondContact O-N 3.17Å
545S36.4Very low46.2Very low117 Ų117101.1 Ų101.182%0.81865%0.651SS**THydrogen-bonded Turntrans-79.517.517350.60000113.6
546S41.9Very low48.4Very low86 Ų86102 Ų10260%0.60164%0.64SS**THydrogen-bonded Turntrans-115.5-8.1177.761.20000114.4T544T544-S546 PolarHBondContact O-N 3.17Å
547A41.6Very low50.9Low45 Ų4595.6 Ų95.637%0.37260%0.601SS.*THydrogen-bonded Turntrans-87.1-32.5-179.900000112.9T549 D550 E551A547-T549 PolarHBondContact O-N 3.37Å; A547-D550 PolarHBondContact O-N 3.4Å; A547-E551 PolarHBondContact O-N 2.91Å; A547-E551 VanDerWaalsContact O-N 3.15Å
548S49.8Very low53.3Low65 Ų6590.4 Ų90.446%0.45556%0.564SS.*Hα-helixtrans-65.4-40.4-17561.40000112.7D550 D552S548-D550 VanDerWaalsContact C-N 3.34Å; S548-D550 PolarHBondContact O-N 3.21Å; S548-D552 VanDerWaalsContact O-CB 3.28Å; S548-D552 WeakPolarHBondContact O-CB 3.3Å; S548-D552 PolarHBondContact O-N 3.04Å; S548-D552 VanDerWaalsContact O-OD2 3.07Å
549T56.5Low55.5Low79 Ų7988.2 Ų88.249%0.48555%0.546SS..Hα-helixtrans-68.2-32.8-179.149.60000113.4A547 M553A547-T549 PolarHBondContact O-N 3.37Å; T549-M553 WeakPolarHBondContact O-CG 3.49Å; T549-M553 PolarHBondContact O-N 3.26Å; T549-M553 VanDerWaalsContact O-N 3.16Å
550D60.8Low58.1Low94 Ų9484.9 Ų84.950%0.50352%0.518SS..Hα-helixtrans-78-42-179.7-78.9-12.4000110.8A547 S548 D552 M553 E554A547-D550 PolarHBondContact O-N 3.4Å; S548-D550 VanDerWaalsContact C-N 3.34Å; S548-D550 PolarHBondContact O-N 3.21Å; D550-D552 VanDerWaalsContact C-N 3.35Å; D550-D552 PolarHBondContact O-N 3.28Å; D550-M553 PolarHBondContact O-N 3.2Å; D550-E554 WeakPolarHBondContact O-CG 3.33Å; D550-E554 PolarHBondContact O-N 3.16Å
551E63.9Low60.4Low130 Ų13077.6 Ų77.661%0.60748%0.479SS*.Hα-helixtrans-63.8-39173.9-70.5-171176.900112.3A547 E554 T555A547-E551 PolarHBondContact O-N 2.91Å; A547-E551 VanDerWaalsContact O-N 3.15Å; E551-E554 PolarHBondContact O-N 3.13Å; E551-T555 WeakPolarHBondContact O-CG2 3.29Å; E551-T555 PolarHBondContact O-N 3.49Å; E551-T555 PolarHBondContact O-OG1 3.44Å
552D68.4Low62.8Low103 Ų10373.8 Ų73.855%0.55145%0.449SS*.Hα-helixtrans-63.7-40.5175-70-22.4000111.5S548 D550 T555 E556S548-D552 VanDerWaalsContact O-CB 3.28Å; S548-D552 WeakPolarHBondContact O-CB 3.3Å; S548-D552 PolarHBondContact O-N 3.04Å; S548-D552 VanDerWaalsContact O-OD2 3.07Å; D550-D552 VanDerWaalsContact C-N 3.35Å; D550-D552 PolarHBondContact O-N 3.28Å; D552-T555 WeakPolarHBondContact CA-OG1 3.46Å; D552-T555 PolarHBondContact O-N 2.99Å; D552-T555 PolarHBondContact O-OG1 3.15Å; D552-E556 WeakPolarHBondContact O-CB 3.24Å; D552-E556 PolarHBondContact O-N 2.84Å
553M69.8Low64.9Low97 Ų9776.2 Ų76.248%0.47844%0.442SS..Hα-helixtrans-70.5-34.1174.8-77.3-150.7-6400113.2T549 D550 A557T549-M553 WeakPolarHBondContact O-CG 3.49Å; T549-M553 PolarHBondContact O-N 3.26Å; T549-M553 VanDerWaalsContact O-N 3.16Å; D550-M553 PolarHBondContact O-N 3.2Å; M553-A557 WeakPolarHBondContact O-CB 3.35Å; M553-A557 PolarHBondContact O-N 3.44Å; M553-A557 VanDerWaalsContact O-N 3.07Å
554E75.8Confident67Low88 Ų8874 Ų7441%0.41142%0.415SS..Hα-helixtrans-67.4-39.1174.4-75.1-165.7175.100112.1I195 R199 D550 E551 V558I195-E554 HydrophobicContact CD1-CB 3.84Å; I195-E554 HydrophobicContact CD1-CG 3.6Å; R199-E554 IonicContact NH2-OE2 3.86Å; D550-E554 WeakPolarHBondContact O-CG 3.33Å; D550-E554 PolarHBondContact O-N 3.16Å; E551-E554 PolarHBondContact O-N 3.13Å; E554-V558 VanDerWaalsContact O-CG2 3.28Å; E554-V558 WeakPolarHBondContact O-CG2 3.46Å; E554-V558 PolarHBondContact O-N 2.91Å; E554-V558 VanDerWaalsContact O-N 3.14Å
555T76.4Confident69.3Low61 Ų6170.8 Ų70.837%0.37439%0.393SS..Hα-helixtrans-69.8-42.1176.751.90000111.7E551 D552 A557 V558 N559E551-T555 WeakPolarHBondContact O-CG2 3.29Å; E551-T555 PolarHBondContact O-N 3.49Å; E551-T555 PolarHBondContact O-OG1 3.44Å; D552-T555 WeakPolarHBondContact CA-OG1 3.46Å; D552-T555 PolarHBondContact O-N 2.99Å; D552-T555 PolarHBondContact O-OG1 3.15Å; T555-A557 PolarHBondContact O-N 3.43Å; T555-V558 PolarHBondContact O-N 3.39Å; T555-N559 VanDerWaalsContact O-CG 3.28Å; T555-N559 PolarHBondContact O-N 3.23Å; T555-N559 PolarHBondContact O-ND2 2.92Å
556E78.5Confident71.3Confident115 Ų11567 Ų6754%0.53737%0.365SS..Hα-helixtrans-58.1-47.2173.2-170.3-173.2-176.200111.6D552 V558 N559 E560D552-E556 WeakPolarHBondContact O-CB 3.24Å; D552-E556 PolarHBondContact O-N 2.84Å; E556-V558 VanDerWaalsContact C-N 3.27Å; E556-V558 PolarHBondContact O-N 3.5Å; E556-N559 PolarHBondContact O-N 3.37Å; E556-E560 PolarHBondContact O-N 3.2Å
557A79.5Confident72.8Confident8 Ų871.8 Ų71.87%0.06638%0.378CS..Hα-helixtrans-63.8-31.4179.100000113.1M553 T555 I561M553-A557 WeakPolarHBondContact O-CB 3.35Å; M553-A557 PolarHBondContact O-N 3.44Å; M553-A557 VanDerWaalsContact O-N 3.07Å; T555-A557 PolarHBondContact O-N 3.43Å; A557-I561 WeakPolarHBondContact O-CD1 3.46Å
558V79.9Confident74.4Confident2 Ų271.6 Ų71.61%0.01237%0.369CS..Hα-helixtrans-74.9-42.3175.1168.30000111.1I195 L196 E554 T555 E556 E560 I561 L562I195-V558 HydrophobicContact CB-CG2 4.14Å; I195-V558 HydrophobicContact CG2-CG2 3.75Å; L196-V558 HydrophobicContact CD1-CG1 4.42Å; L196-V558 HydrophobicContact CD2-CG1 3.72Å; L196-V558 HydrophobicContact CG-CG1 4.08Å; L196-V558 HydrophobicContact CG-CG2 4.24Å; E554-V558 VanDerWaalsContact O-CG2 3.28Å; E554-V558 WeakPolarHBondContact O-CG2 3.46Å; E554-V558 PolarHBondContact O-N 2.91Å; E554-V558 VanDerWaalsContact O-N 3.14Å; T555-V558 PolarHBondContact O-N 3.39Å; E556-V558 VanDerWaalsContact C-N 3.27Å; E556-V558 PolarHBondContact O-N 3.5Å; V558-E560 VanDerWaalsContact C-N 3.34Å; V558-E560 PolarHBondContact O-N 3.34Å; V558-I561 PolarHBondContact O-N 3.12Å; V558-I561 VanDerWaalsContact O-N 3.13Å; V558-L562 HydrophobicContact CG1-CD1 3.95Å; V558-L562 HydrophobicContact CG1-CG 4.43Å; V558-L562 WeakPolarHBondContact O-CG 3.28Å; V558-L562 PolarHBondContact O-N 3.02Å; V558-L562 VanDerWaalsContact O-N 3.16Å
559N80.9Confident75.6Confident86 Ų8672.9 Ų72.946%0.4637%0.368SS..Hα-helixtrans-61.2-41.7177.8-70.8-18.2000112T555 E556 I561 L562 E563T555-N559 VanDerWaalsContact O-CG 3.28Å; T555-N559 PolarHBondContact O-N 3.23Å; T555-N559 PolarHBondContact O-ND2 2.92Å; E556-N559 PolarHBondContact O-N 3.37Å; N559-I561 PolarHBondContact O-N 3.41Å; N559-L562 PolarHBondContact O-N 3.05Å; N559-L562 VanDerWaalsContact O-N 3.09Å; N559-E563 WeakPolarHBondContact O-CG 3.38Å; N559-E563 PolarHBondContact O-N 2.91Å
560E82.5Confident76.7Confident39 Ų3969.8 Ų69.818%0.18235%0.348CS..Hα-helixtrans-56.9-32.8175.5-164.4-159.6141.700112.7Q185 K242 E556 V558Q185-E560 WeakPolarHBondContact CG-OE1 3.26Å; Q185-E560 PolarHBondContact NE2-OE1 3.45Å; K242-E560 IonicContact NZ-OE1 2.72Å; K242-E560 PolarHBondContact NZ-OE1 3.45Å; E556-E560 PolarHBondContact O-N 3.2Å; V558-E560 VanDerWaalsContact C-N 3.34Å; V558-E560 PolarHBondContact O-N 3.34Å
561I81.8Confident77.9Confident4 Ų466.1 Ų66.12%0.02133%0.329CS..Hα-helixtrans-77.3-40.4178.6-66.8161.2000110.6L193 L196 A557 V558 N559 E563 D564 I565L193-I561 HydrophobicContact CB-CD1 4.34Å; L193-I561 HydrophobicContact CD2-CD1 4.05Å; L193-I561 HydrophobicContact CD2-CG2 3.83Å; L193-I561 HydrophobicContact CG-CD1 3.77Å; L193-I561 HydrophobicContact CG-CG1 4.47Å; L196-I561 HydrophobicContact CD1-CB 4.26Å; L196-I561 HydrophobicContact CD1-CD1 4.24Å; L196-I561 HydrophobicContact CD1-CG2 3.84Å; A557-I561 WeakPolarHBondContact O-CD1 3.46Å; V558-I561 PolarHBondContact O-N 3.12Å; V558-I561 VanDerWaalsContact O-N 3.13Å; N559-I561 PolarHBondContact O-N 3.41Å; I561-E563 VanDerWaalsContact C-N 3.27Å; I561-E563 PolarHBondContact O-N 3.08Å; I561-D564 PolarHBondContact O-N 2.84Å; I561-D564 VanDerWaalsContact O-N 3.1Å; I561-I565 HydrophobicContact CG2-CD1 4.15Å; I561-I565 HydrophobicContact CG2-CG1 4.5Å; I561-I565 WeakPolarHBondContact O-CG1 3.49Å; I561-I565 PolarHBondContact O-N 2.93Å
562L81.3Confident79Confident43 Ų4362.3 Ų62.323%0.22531%0.309CS..Hα-helixtrans-65.4-33.2-179-64.6164.5000112.1P211 V558 N559 D564 I565P211-L562 HydrophobicContact CB-CD1 3.92Å; P211-L562 HydrophobicContact CB-CD2 4.06Å; P211-L562 HydrophobicContact CG-CD1 3.17Å; P211-L562 HydrophobicContact CG-CD2 4.09Å; P211-L562 HydrophobicContact CG-CG 4.26Å; V558-L562 HydrophobicContact CG1-CD1 3.95Å; V558-L562 HydrophobicContact CG1-CG 4.43Å; V558-L562 WeakPolarHBondContact O-CG 3.28Å; V558-L562 PolarHBondContact O-N 3.02Å; V558-L562 VanDerWaalsContact O-N 3.16Å; N559-L562 PolarHBondContact O-N 3.05Å; N559-L562 VanDerWaalsContact O-N 3.09Å; L562-D564 PolarHBondContact O-N 3.23Å; L562-I565 HydrophobicContact CD2-CD1 4.33Å; L562-I565 PolarHBondContact O-N 3.04Å
563E83.6Confident80Confident157 Ų15757.4 Ų57.473%0.73428%0.283SS*.Hα-helixtrans-62.2-31.2172.9-72.1178.1-174.900112.9N559 I561N559-E563 WeakPolarHBondContact O-CG 3.38Å; N559-E563 PolarHBondContact O-N 2.91Å; I561-E563 VanDerWaalsContact C-N 3.27Å; I561-E563 PolarHBondContact O-N 3.08Å
564D83.1Confident80.9Confident20 Ų2054.2 Ų54.211%0.10727%0.268CS..Hα-helixtrans-89.7-7.9179.7-74.8-30.7000112.8K242 A245 R249 I561 L562K242-D564 HydrophobicContact CD-CB 4.22Å; K242-D564 WeakPolarHBondContact CD-OD2 3.32Å; K242-D564 WeakPolarHBondContact CE-OD2 3.38Å; K242-D564 IonicContact NZ-OD2 3.38Å; K242-D564 PolarHBondContact NZ-OD2 3.46Å; A245-D564 HydrophobicContact CB-CB 3.86Å; R249-D564 IonicContact CZ-OD1 2.78Å; R249-D564 IonicContact NH1-OD1 3.46Å; R249-D564 IonicContact NH2-OD1 3.83Å; R249-D564 PolarHBondContact NH2-OD1 3.47Å; I561-D564 PolarHBondContact O-N 2.84Å; I561-D564 VanDerWaalsContact O-N 3.1Å; L562-D564 PolarHBondContact O-N 3.23Å
565I82.7Confident81.4Confident48 Ų4851 Ų5125%0.24626%0.255CS..SBendtrans-82.7119.6173.6-67.6172.3000108.4L213 I561 L562L213-I565 HydrophobicContact CD1-CD1 3.66Å; L213-I565 HydrophobicContact CD2-CD1 3.77Å; L213-I565 HydrophobicContact CG-CD1 4.36Å; I561-I565 HydrophobicContact CG2-CD1 4.15Å; I561-I565 HydrophobicContact CG2-CG1 4.5Å; I561-I565 WeakPolarHBondContact O-CG1 3.49Å; I561-I565 PolarHBondContact O-N 2.93Å; L562-I565 HydrophobicContact CD2-CD1 4.33Å; L562-I565 PolarHBondContact O-N 3.04Å
566P79.4Confident81.9Confident36 Ų3651.8 Ų51.823%0.23426%0.259CS..  trans-66.5141.4-178.126-32.6000111.6H568 D571P566-H568 PolarHBondContact O-N 3.17Å; P566-D571 HydrophobicContact CB-CB 3.52Å; P566-D571 WeakPolarHBondContact CB-OD2 3.42Å; P566-D571 HydrophobicContact CG-CB 3.96Å
567E72.8Confident82.5Confident188 Ų18846.4 Ų46.488%0.87923%0.234SC*.SBendtrans-65.8-26174.9-63.8-173.3172.800112.6
568H75Confident83Confident40 Ų4051.7 Ų51.719%0.18526%0.258CS..SBendtrans-107.7122.1-179.4-162.7-27.8000111.2P566 E570 D571P566-H568 PolarHBondContact O-N 3.17Å; H568-E570 IonicContact CE1-OE2 2.91Å; H568-E570 PolarHBondContact ND1-N 3.28Å; H568-E570 PolarHBondContact O-N 3.36Å; H568-D571 WeakPolarHBondContact O-CB 3.38Å; H568-D571 PolarHBondContact O-N 3.46Å
569E74.5Confident83.6Confident93 Ų9353.7 Ų53.744%0.43527%0.268SS..THydrogen-bonded Turntrans-57.6-24.1-179-62.4174.5-178.800114.7G220 Y572G220-E569 WeakPolarHBondContact CA-OE1 3.42Å; G220-E569 WeakPolarHBondContact CA-OE2 3.4Å; E569-Y572 WeakPolarHBondContact O-CD1 3.33Å; E569-Y572 WeakPolarHBondContact O-CE1 3.48Å
570E81.1Confident84.2Confident13 Ų1349.7 Ų49.76%0.06125%0.247CC..THydrogen-bonded Turntrans-98.710.2-177.2-59.6-171.2151.500112.2K329 K334 L395 H568 Y572 L573K329-E570 IonicContact NZ-OE1 3.33Å; K329-E570 PolarHBondContact NZ-OE1 3.06Å; K334-E570 IonicContact NZ-OE2 2.85Å; K334-E570 PolarHBondContact NZ-OE2 3.38Å; L395-E570 HydrophobicContact CD1-CB 4.02Å; H568-E570 IonicContact CE1-OE2 2.91Å; H568-E570 PolarHBondContact ND1-N 3.28Å; H568-E570 PolarHBondContact O-N 3.36Å; E570-Y572 PolarHBondContact O-N 3.41Å; E570-Y572 VanDerWaalsContact O-N 3.15Å; E570-L573 HydrophobicContact CB-CD1 4.3Å; E570-L573 WeakPolarHBondContact O-CB 3.31Å; E570-L573 PolarHBondContact O-N 3.07Å
571D85.3Confident84.7Confident18 Ų1852.2 Ų52.210%0.09626%0.259CS..G310 helixtrans-56.8-31.1-178.2171.174.4000113.2K248 Q391 P566 H568 L573 D574K248-D571 IonicContact NZ-OD1 3.44Å; K248-D571 PolarHBondContact NZ-OD1 3.19Å; K248-D571 IonicContact NZ-OD2 2.8Å; K248-D571 PolarHBondContact NZ-OD2 2.84Å; Q391-D571 PolarHBondContact NE2-OD1 3.14Å; P566-D571 HydrophobicContact CB-CB 3.52Å; P566-D571 WeakPolarHBondContact CB-OD2 3.42Å; P566-D571 HydrophobicContact CG-CB 3.96Å; H568-D571 WeakPolarHBondContact O-CB 3.38Å; H568-D571 PolarHBondContact O-N 3.46Å; D571-L573 PolarHBondContact O-N 3.3Å; D571-D574 WeakPolarHBondContact O-CB 3.39Å; D571-D574 PolarHBondContact O-N 2.89Å
572Y87Confident85.4Confident50 Ų5057.3 Ų57.320%0.19629%0.285CS..G310 helixtrans-69.5-15175.974.4-86.9000114.3V282 L338 E569 E570V282-Y572 HydrophobicContact CG1-CD2 4.09Å; V282-Y572 HydrophobicContact CG2-CD2 4.31Å; V282-Y572 HydrophobicContact CG2-CE2 4.02Å; L338-Y572 HydrophobicContact CD1-CE2 4.19Å; L338-Y572 HydrophobicContact CD2-CD2 4.31Å; L338-Y572 HydrophobicContact CD2-CE2 4.34Å; E569-Y572 WeakPolarHBondContact O-CD1 3.33Å; E569-Y572 WeakPolarHBondContact O-CE1 3.48Å; E570-Y572 PolarHBondContact O-N 3.41Å; E570-Y572 VanDerWaalsContact O-N 3.15Å
573L89.2Confident86Confident0 Ų055.9 Ų55.90%028%0.277CS..G310 helixtrans-89-10.9172.7-58.6177.8000112K334 E335 L338 L395 R398 E570 D571 S575K334-L573 HydrophobicContact CB-CD1 4.04Å; E335-L573 HydrophobicContact CG-CD1 4.1Å; L338-L573 HydrophobicContact CD1-CD2 3.87Å; L338-L573 HydrophobicContact CD2-CD2 3.97Å; L338-L573 HydrophobicContact CG-CD2 3.75Å; L395-L573 HydrophobicContact CD2-CB 3.99Å; R398-L573 PolarHBondContact NH1-O 3.33Å; E570-L573 HydrophobicContact CB-CD1 4.3Å; E570-L573 WeakPolarHBondContact O-CB 3.31Å; E570-L573 PolarHBondContact O-N 3.07Å; D571-L573 PolarHBondContact O-N 3.3Å; L573-S575 PolarHBondContact O-N 3.48Å; L573-S575 VanDerWaalsContact O-N 3.11Å
574D89Confident86.6Confident30 Ų3048.8 Ų48.816%0.1624%0.244CC..  trans-82.885.9-179.6-172.728.7000111.3Q391 R394 L395 D571Q391-D574 VanDerWaalsContact CB-OD2 3.3Å; Q391-D574 WeakPolarHBondContact CB-OD2 3.11Å; Q391-D574 HydrophobicContact CG-CB 4.07Å; Q391-D574 WeakPolarHBondContact CG-OD2 3.34Å; Q391-D574 PolarHBondContact NE2-OD2 3.46Å; R394-D574 IonicContact CZ-OD1 3.51Å; R394-D574 IonicContact CZ-OD2 2.71Å; R394-D574 IonicContact NE-OD1 3.17Å; R394-D574 PolarHBondContact NE-OD1 3.23Å; R394-D574 IonicContact NE-OD2 2.67Å; R394-D574 VanDerWaalsContact NH2-CG 3.32Å; R394-D574 IonicContact NH2-OD1 3.83Å; R394-D574 PolarHBondContact NH2-OD1 3.4Å; R394-D574 VanDerWaalsContact NH2-OD1 3.16Å; R394-D574 IonicContact NH2-OD2 3.64Å; R394-D574 PolarHBondContact NH2-OD2 3.12Å; L395-D574 HydrophobicContact CD2-CB 4.33Å; L395-D574 HydrophobicContact CG-CB 4.43Å; D571-D574 WeakPolarHBondContact O-CB 3.39Å; D571-D574 PolarHBondContact O-N 2.89Å
575S85.9Confident87.1Confident21 Ų2150.7 Ų50.715%0.14726%0.263CS..  trans-107.5150171-1770000111.1R398 L573 L577R398-S575 VanDerWaalsContact CZ-O 3.29Å; R398-S575 PolarHBondContact NH1-O 3.29Å; R398-S575 VanDerWaalsContact NH1-O 3.1Å; R398-S575 PolarHBondContact NH2-O 2.95Å; L573-S575 PolarHBondContact O-N 3.48Å; L573-S575 VanDerWaalsContact O-N 3.11Å; S575-L577 PolarHBondContact OG-N 3.46Å; S575-L577 VanDerWaalsContact OG-N 3.12Å
576T87.3Confident87.6Confident76 Ų7652 Ų5247%0.46627%0.268SS..  trans-82.9-16.7167.557.40000112.5E578T576-E578 PolarHBondContact O-N 3.32Å
577L90.7Very high88.2Confident2 Ų250.8 Ų50.81%0.0126%0.259CS..  trans63.97.1-175.2-53.8175.6000115.5V337 L340 F370 L373 S575 E580 E581V337-L577 HydrophobicContact CG1-CD2 4.08Å; L340-L577 HydrophobicContact CD1-CD1 4.2Å; L340-L577 HydrophobicContact CD1-CD2 4.12Å; L340-L577 HydrophobicContact CD2-CD2 4.4Å; F370-L577 HydrophobicContact CD2-CB 4.04Å; F370-L577 HydrophobicContact CD2-CD1 4.32Å; F370-L577 HydrophobicContact CE2-CB 3.81Å; L373-L577 HydrophobicContact CB-CD1 3.75Å; S575-L577 PolarHBondContact OG-N 3.46Å; S575-L577 VanDerWaalsContact OG-N 3.12Å; L577-E580 WeakPolarHBondContact CA-OE2 3.31Å; L577-E580 PolarHBondContact O-N 2.97Å; L577-E581 PolarHBondContact O-N 3.1Å
578E90.8Very high89.2Confident120 Ų12042.1 Ų42.156%0.56122%0.219SC*.Hα-helixtrans-62.7-47.4-179.5-68.7167.9-163.300112.2T576 E580 E581 I582T576-E578 PolarHBondContact O-N 3.32Å; E578-E580 VanDerWaalsContact C-N 3.33Å; E578-E580 PolarHBondContact O-N 3.4Å; E578-E581 PolarHBondContact O-N 2.93Å; E578-I582 WeakPolarHBondContact O-CG1 3.26Å; E578-I582 PolarHBondContact O-N 2.82Å
579D90.6Very high90Very high43 Ų4342.3 Ų42.323%0.2322%0.224CC..Hα-helixtrans-61.4-44.3177.3-82.5-5.8000110W289 R293 E581 I582 I583W289-D579 HydrophobicContact CH2-CB 4.46Å; W289-D579 HydrophobicContact CZ2-CB 4.29Å; R293-D579 IonicContact CZ-OD2 2.94Å; R293-D579 IonicContact NH1-OD2 2.75Å; R293-D579 PolarHBondContact NH1-OD2 3.29Å; R293-D579 IonicContact NH2-OD2 3.99Å; D579-E581 PolarHBondContact O-N 3.14Å; D579-I582 PolarHBondContact O-N 3.39Å; D579-I583 VanDerWaalsContact O-CD1 3.23Å; D579-I583 WeakPolarHBondContact O-CD1 3.37Å; D579-I583 WeakPolarHBondContact O-CG1 3.23Å; D579-I583 PolarHBondContact O-N 3.12Å; D579-I583 VanDerWaalsContact O-N 3.09Å
580E93.9Very high90.7Very high2 Ų240.3 Ų40.31%0.00921%0.213CC..Hα-helixtrans-63.1-39.3178.3-7096.9142.600113.4W289 L340 R341 L344 L577 E578 I582 I583 I584W289-E580 HydrophobicContact CH2-CG 4.38Å; L340-E580 HydrophobicContact CD2-CB 3.82Å; L340-E580 HydrophobicContact CD2-CG 3.72Å; R341-E580 IonicContact CZ-OE1 3.79Å; R341-E580 IonicContact NE-OE1 3.64Å; R341-E580 PolarHBondContact NE-OE1 2.88Å; R341-E580 IonicContact NH2-OE1 3.69Å; R341-E580 PolarHBondContact NH2-OE1 3.01Å; R341-E580 IonicContact NH2-OE2 2.75Å; R341-E580 PolarHBondContact NH2-OE2 3.45Å; L344-E580 HydrophobicContact CD2-CB 3.89Å; L344-E580 HydrophobicContact CD2-CG 3.66Å; L577-E580 WeakPolarHBondContact CA-OE2 3.31Å; L577-E580 PolarHBondContact O-N 2.97Å; E578-E580 VanDerWaalsContact C-N 3.33Å; E578-E580 PolarHBondContact O-N 3.4Å; E580-I582 PolarHBondContact O-N 3.38Å; E580-I583 PolarHBondContact O-N 3.2Å; E580-I584 HydrophobicContact CB-CD1 4.39Å; E580-I584 VanDerWaalsContact O-CB 3.27Å; E580-I584 WeakPolarHBondContact O-CB 3.37Å; E580-I584 WeakPolarHBondContact O-CD1 3.44Å; E580-I584 WeakPolarHBondContact O-CG1 3.2Å; E580-I584 PolarHBondContact O-N 3.42Å
581E94.4Very high90.9Very high92 Ų9239.8 Ų39.843%0.4321%0.211SC..Hα-helixtrans-57-51.1176.9-175.6175.4-166.400111.2F370 L577 E578 D579 I583 I584 A585F370-E581 HydrophobicContact CD2-CB 4.47Å; F370-E581 HydrophobicContact CE1-CB 4.33Å; F370-E581 HydrophobicContact CE1-CG 3.92Å; F370-E581 HydrophobicContact CE2-CB 3.66Å; F370-E581 HydrophobicContact CE2-CG 4.16Å; F370-E581 HydrophobicContact CZ-CB 3.58Å; F370-E581 VanDerWaalsContact CZ-CD 3.45Å; F370-E581 HydrophobicContact CZ-CG 3.55Å; L577-E581 PolarHBondContact O-N 3.1Å; E578-E581 PolarHBondContact O-N 2.93Å; D579-E581 PolarHBondContact O-N 3.14Å; E581-I583 PolarHBondContact O-N 2.9Å; E581-I584 PolarHBondContact O-N 3.04Å; E581-A585 WeakPolarHBondContact O-CB 3.33Å; E581-A585 PolarHBondContact O-N 3.19Å
582I95.2Very high90.9Very high111 Ų11142.2 Ų42.257%0.56922%0.222SC*.Hα-helixtrans-60.4-47.6-179.2-63.6168.1000109.9E578 D579 E580 A585 E586E578-I582 WeakPolarHBondContact O-CG1 3.26Å; E578-I582 PolarHBondContact O-N 2.82Å; D579-I582 PolarHBondContact O-N 3.39Å; E580-I582 PolarHBondContact O-N 3.38Å; I582-A585 PolarHBondContact O-N 3.01Å; I582-E586 WeakPolarHBondContact O-CB 3.49Å; I582-E586 PolarHBondContact O-N 3.06Å
583I94.4Very high90.6Very high14 Ų1445 Ų457%0.07224%0.24CC..Hα-helixtrans-68.7-40.1-176.8-61.1159.2000111.2W289 F292 L344 I348 D579 E580 E581 A585 E586 Y587W289-I583 HydrophobicContact CH2-CD1 3.52Å; W289-I583 HydrophobicContact CZ2-CD1 4.3Å; W289-I583 HydrophobicContact CZ3-CD1 4.15Å; F292-I583 HydrophobicContact CE1-CD1 3.66Å; F292-I583 HydrophobicContact CE1-CG1 4.21Å; F292-I583 HydrophobicContact CE1-CG2 4.25Å; F292-I583 HydrophobicContact CZ-CD1 4.27Å; F292-I583 HydrophobicContact CZ-CG1 4.35Å; F292-I583 HydrophobicContact CZ-CG2 3.85Å; L344-I583 HydrophobicContact CD1-CG2 3.98Å; L344-I583 HydrophobicContact CD2-CB 4.35Å; L344-I583 HydrophobicContact CD2-CG2 4.31Å; L344-I583 HydrophobicContact CG-CG2 4.44Å; I348-I583 HydrophobicContact CD1-CG2 3.64Å; I348-I583 HydrophobicContact CG1-CG2 4.44Å; D579-I583 VanDerWaalsContact O-CD1 3.23Å; D579-I583 WeakPolarHBondContact O-CD1 3.37Å; D579-I583 WeakPolarHBondContact O-CG1 3.23Å; D579-I583 PolarHBondContact O-N 3.12Å; D579-I583 VanDerWaalsContact O-N 3.09Å; E580-I583 PolarHBondContact O-N 3.2Å; E581-I583 PolarHBondContact O-N 2.9Å; I583-A585 VanDerWaalsContact C-N 3.35Å; I583-E586 PolarHBondContact O-N 3.34Å; I583-Y587 HydrophobicContact CG2-CD2 3.79Å; I583-Y587 HydrophobicContact CG2-CE2 4.06Å; I583-Y587 WeakPolarHBondContact O-CD2 3.42Å; I583-Y587 PolarHBondContact O-N 3.01Å
584I95.4Very high89.5Confident7 Ų748.3 Ų48.34%0.03625%0.252CS..Hα-helixtrans-59.3-48.7175.3-73.7164.3000109.6L340 L344 A366 R367 F370 E580 E581 L588L340-I584 HydrophobicContact CD2-CD1 4.35Å; L344-I584 HydrophobicContact CD1-CG1 3.58Å; L344-I584 HydrophobicContact CD2-CG1 4.21Å; L344-I584 HydrophobicContact CG-CG1 4.38Å; A366-I584 HydrophobicContact CB-CD1 4.04Å; A366-I584 HydrophobicContact CB-CG1 4.27Å; R367-I584 HydrophobicContact CB-CG2 3.92Å; R367-I584 HydrophobicContact CG-CG2 4.41Å; F370-I584 HydrophobicContact CB-CD1 4.22Å; E580-I584 HydrophobicContact CB-CD1 4.39Å; E580-I584 VanDerWaalsContact O-CB 3.27Å; E580-I584 WeakPolarHBondContact O-CB 3.37Å; E580-I584 WeakPolarHBondContact O-CD1 3.44Å; E580-I584 WeakPolarHBondContact O-CG1 3.2Å; E580-I584 PolarHBondContact O-N 3.42Å; E581-I584 PolarHBondContact O-N 3.04Å; I584-L588 HydrophobicContact CG2-CD1 3.65Å; I584-L588 HydrophobicContact CG2-CG 4.36Å; I584-L588 VanDerWaalsContact O-CB 3.25Å; I584-L588 WeakPolarHBondContact O-CB 3.47Å; I584-L588 VanDerWaalsContact O-CG 3.27Å; I584-L588 WeakPolarHBondContact O-CG 3.24Å; I584-L588 PolarHBondContact O-N 3.45Å
585A94.4Very high88.3Confident60 Ų6050.4 Ų50.450%0.49626%0.26SS..Hα-helixtrans-62-45.4179.400000111.7E581 I582 I583 S589E581-A585 WeakPolarHBondContact O-CB 3.33Å; E581-A585 PolarHBondContact O-N 3.19Å; I582-A585 PolarHBondContact O-N 3.01Å; I583-A585 VanDerWaalsContact C-N 3.35Å; A585-S589 WeakPolarHBondContact O-CB 3.39Å; A585-S589 PolarHBondContact O-N 2.89Å
586E93.4Very high87Confident75 Ų7552 Ų5235%0.3527%0.271SS..Hα-helixtrans-58-54.8178.2-170.1-166.2167.500111.4I582 I583 L588 S589 Y590I582-E586 WeakPolarHBondContact O-CB 3.49Å; I582-E586 PolarHBondContact O-N 3.06Å; I583-E586 PolarHBondContact O-N 3.34Å; E586-L588 PolarHBondContact O-N 3.14Å; E586-S589 WeakPolarHBondContact O-CB 3.39Å; E586-S589 PolarHBondContact O-N 3.39Å; E586-S589 PolarHBondContact O-OG 3.28Å; E586-Y590 HydrophobicContact CG-CE1 4.41Å; E586-Y590 PolarHBondContact OE1-OH 3.45Å; E586-Y590 WeakPolarHBondContact OE1-CE2 3.36Å; E586-Y590 WeakPolarHBondContact CG-OH 3.33Å; E586-Y590 HydrophobicContact CG-CE2 3.66Å; E586-Y590 PolarHBondContact O-N 3.35Å
587Y92.4Very high85.5Confident12 Ų1250.3 Ų50.35%0.04727%0.265CS..Hα-helixtrans-71.5-32.5-176.5-85.4-97.7000113.3F292 I348 Y351 H352 I583 S589 Y590 V591F292-Y587 HydrophobicContact CE2-CE2 4.04Å; F292-Y587 HydrophobicContact CZ-CE2 4.16Å; I348-Y587 HydrophobicContact CB-CD1 4.44Å; I348-Y587 HydrophobicContact CB-CE1 4.18Å; I348-Y587 HydrophobicContact CD1-CE2 4.43Å; I348-Y587 HydrophobicContact CG1-CD1 3.95Å; I348-Y587 HydrophobicContact CG1-CD2 4.03Å; I348-Y587 HydrophobicContact CG1-CE1 3.98Å; I348-Y587 HydrophobicContact CG1-CE2 4.07Å; I348-Y587 HydrophobicContact CG1-CG 3.97Å; I348-Y587 HydrophobicContact CG2-CE1 3.8Å; Y351-Y587 AromaticContact CD1-CD1 3.95Å; Y351-Y587 HydrophobicContact CD1-CD1 3.95Å; Y351-Y587 AromaticContact CD1-CE1 3.74Å; Y351-Y587 HydrophobicContact CD1-CE1 3.74Å; Y351-Y587 HydrophobicContact CE1-CE1 4.35Å; Y351-Y587 HydrophobicContact CG-CD1 4.11Å; Y351-Y587 HydrophobicContact CG-CE1 4.32Å; H352-Y587 AromaticContact NE2-CE1 3.58Å; H352-Y587 AromaticContact NE2-CZ 3.67Å; H352-Y587 PolarHBondContact NE2-OH 2.93Å; I583-Y587 HydrophobicContact CG2-CD2 3.79Å; I583-Y587 HydrophobicContact CG2-CE2 4.06Å; I583-Y587 WeakPolarHBondContact O-CD2 3.42Å; I583-Y587 PolarHBondContact O-N 3.01Å; Y587-S589 VanDerWaalsContact C-N 3.33Å; Y587-Y590 HydrophobicContact CD1-CD2 4.28Å; Y587-Y590 HydrophobicContact CG-CD2 4.33Å; Y587-Y590 PolarHBondContact O-N 2.91Å; Y587-V591 WeakPolarHBondContact O-CG2 3.43Å; Y587-V591 PolarHBondContact O-N 3.39Å
588L92.9Very high83.6Confident6 Ų654 Ų543%0.03129%0.288CS..Hα-helixtrans-63.5-41.5171.2-78.5173.6000111.2Y360 L363 R367 I584 E586 Y590 V591 E592Y360-L588 HydrophobicContact CD2-CD2 4.42Å; Y360-L588 HydrophobicContact CE2-CD2 4.49Å; L363-L588 HydrophobicContact CB-CD2 3.55Å; L363-L588 HydrophobicContact CB-CG 4Å; L363-L588 HydrophobicContact CD1-CD2 4.28Å; R367-L588 HydrophobicContact CB-CD1 4.22Å; R367-L588 HydrophobicContact CG-CD1 4.42Å; I584-L588 HydrophobicContact CG2-CD1 3.65Å; I584-L588 HydrophobicContact CG2-CG 4.36Å; I584-L588 VanDerWaalsContact O-CB 3.25Å; I584-L588 WeakPolarHBondContact O-CB 3.47Å; I584-L588 VanDerWaalsContact O-CG 3.27Å; I584-L588 WeakPolarHBondContact O-CG 3.24Å; I584-L588 PolarHBondContact O-N 3.45Å; E586-L588 PolarHBondContact O-N 3.14Å; L588-Y590 PolarHBondContact O-N 2.92Å; L588-V591 VanDerWaalsContact O-N 3.16Å; L588-V591 PolarHBondContact O-N 2.86Å; L588-E592 VanDerWaalsContact O-CB 3.31Å; L588-E592 WeakPolarHBondContact O-CB 3.26Å; L588-E592 WeakPolarHBondContact O-CG 3.49Å; L588-E592 PolarHBondContact O-N 2.87Å
589S91.4Very high81.4Confident44 Ų4456.5 Ų56.531%0.30830%0.297SS..Hα-helixtrans-58.8-38.7176.283.40000111.8A585 E586 Y587 N593A585-S589 WeakPolarHBondContact O-CB 3.39Å; A585-S589 PolarHBondContact O-N 2.89Å; E586-S589 WeakPolarHBondContact O-CB 3.39Å; E586-S589 PolarHBondContact O-N 3.39Å; E586-S589 PolarHBondContact O-OG 3.28Å; Y587-S589 VanDerWaalsContact C-N 3.33Å; S589-N593 VanDerWaalsContact O-CB 3.23Å; S589-N593 WeakPolarHBondContact O-CB 3.4Å; S589-N593 PolarHBondContact O-N 3.04Å; S589-N593 PolarHBondContact O-ND2 2.92Å; S589-N593 VanDerWaalsContact O-ND2 3.07Å
590Y89.3Confident79Confident50 Ų5063 Ų6320%0.19632%0.323CS..Hα-helixtrans-64.3-41.6176.9-62.6-27.1000112.9A2 Y351 E586 Y587 L588 R594A2-Y590 HydrophobicContact CB-CE2 4.36Å; Y351-Y590 HydrophobicContact CE1-CD2 4.38Å; E586-Y590 HydrophobicContact CG-CE1 4.41Å; E586-Y590 PolarHBondContact OE1-OH 3.45Å; E586-Y590 WeakPolarHBondContact OE1-CE2 3.36Å; E586-Y590 WeakPolarHBondContact CG-OH 3.33Å; E586-Y590 HydrophobicContact CG-CE2 3.66Å; E586-Y590 PolarHBondContact O-N 3.35Å; Y587-Y590 HydrophobicContact CD1-CD2 4.28Å; Y587-Y590 HydrophobicContact CG-CD2 4.33Å; Y587-Y590 PolarHBondContact O-N 2.91Å; L588-Y590 PolarHBondContact O-N 2.92Å; Y590-R594 WeakPolarHBondContact O-CG 3.49Å
591V86.8Confident76.3Confident2 Ų271.7 Ų71.71%0.01237%0.37CS..Hα-helixtrans-75.9-40.1-179.9179.60000111.6Y351 A359 Y360 L363 Y587 L588 R594 K595Y351-V591 HydrophobicContact CD2-CG2 3.62Å; Y351-V591 HydrophobicContact CE2-CG2 4.05Å; A359-V591 HydrophobicContact CB-CG2 4.48Å; Y360-V591 HydrophobicContact CD2-CG1 3.78Å; Y360-V591 HydrophobicContact CG-CG1 4.27Å; L363-V591 HydrophobicContact CD1-CG2 4.07Å; Y587-V591 WeakPolarHBondContact O-CG2 3.43Å; Y587-V591 PolarHBondContact O-N 3.39Å; L588-V591 VanDerWaalsContact O-N 3.16Å; L588-V591 PolarHBondContact O-N 2.86Å; V591-R594 PolarHBondContact O-N 3Å; V591-K595 PolarHBondContact O-N 3.25Å
592E85.4Confident75.4Confident70 Ų7070.7 Ų70.733%0.32737%0.367SS..Hα-helixtrans-72.1-41.7-176.6-72.2-179.9168.500112.5Y360 R367 L588 R594 K595 S596Y360-E592 HydrophobicContact CE2-CG 3.93Å; R367-E592 IonicContact NH1-OE1 3.57Å; L588-E592 VanDerWaalsContact O-CB 3.31Å; L588-E592 WeakPolarHBondContact O-CB 3.26Å; L588-E592 WeakPolarHBondContact O-CG 3.49Å; L588-E592 PolarHBondContact O-N 2.87Å; E592-R594 PolarHBondContact O-N 3.22Å; E592-R594 VanDerWaalsContact O-N 3.12Å; E592-K595 PolarHBondContact O-N 2.8Å; E592-S596 PolarHBondContact O-N 3.27Å; E592-S596 PolarHBondContact O-OG 2.71Å
593N79Confident74.4Confident107 Ų10768.6 Ų68.657%0.57236%0.356SS*.Hα-helixtrans-56.9-30.7176.3-75.4-24.9000112.2S589 S596 A597S589-N593 VanDerWaalsContact O-CB 3.23Å; S589-N593 WeakPolarHBondContact O-CB 3.4Å; S589-N593 PolarHBondContact O-N 3.04Å; S589-N593 PolarHBondContact O-ND2 2.92Å; S589-N593 VanDerWaalsContact O-ND2 3.07Å; N593-S596 WeakPolarHBondContact CA-OG 3.15Å; N593-S596 PolarHBondContact O-OG 3.07Å; N593-A597 PolarHBondContact O-N 3.43Å
594R67.8Low73.2Confident70 Ų7071.6 Ų71.626%0.26437%0.372SS..Hα-helixtrans-82.4-33.1176.6-59.1-169.8110.6-110.7-7.5113Y6 Y590 V591 E592 S596 A597 T598Y6-R594 VanDerWaalsContact CE1-CZ 3.44Å; Y6-R594 PolarHBondContact OH-NH1 2.83Å; Y590-R594 WeakPolarHBondContact O-CG 3.49Å; V591-R594 PolarHBondContact O-N 3Å; E592-R594 PolarHBondContact O-N 3.22Å; E592-R594 VanDerWaalsContact O-N 3.12Å; R594-S596 VanDerWaalsContact C-N 3.29Å; R594-S596 PolarHBondContact O-N 3.34Å; R594-A597 PolarHBondContact O-N 2.98Å; R594-T598 VanDerWaalsContact O-N 3.13Å; R594-T598 PolarHBondContact O-OG1 3.17Å; R594-T598 PolarHBondContact O-N 2.95Å
595K62.4Low71.9Confident74 Ų7475.4 Ų75.432%0.32239%0.391SS..Hα-helixtrans-64.6-33.3169.8-77-172.3177-177.70112.5Y360 V591 E592 T598 K599Y360-K595 HydrophobicContact CD2-CD 4.49Å; V591-K595 PolarHBondContact O-N 3.25Å; E592-K595 PolarHBondContact O-N 2.8Å; K595-T598 VanDerWaalsContact CA-OG1 3.29Å; K595-T598 WeakPolarHBondContact CA-OG1 3.41Å; K595-T598 PolarHBondContact O-OG1 3.25Å; K595-T598 VanDerWaalsContact O-OG1 3.08Å; K595-K599 WeakPolarHBondContact O-CB 3.38Å; K595-K599 WeakPolarHBondContact O-CG 3.41Å; K595-K599 PolarHBondContact O-N 3.36Å
596S58.3Low70.5Confident54 Ų5476.4 Ų76.438%0.37839%0.385SS..Hα-helixtrans-75.1-27.3175.253.80000113.7E592 N593 R594 K600E592-S596 PolarHBondContact O-N 3.27Å; E592-S596 PolarHBondContact O-OG 2.71Å; N593-S596 WeakPolarHBondContact CA-OG 3.15Å; N593-S596 PolarHBondContact O-OG 3.07Å; R594-S596 VanDerWaalsContact C-N 3.29Å; R594-S596 PolarHBondContact O-N 3.34Å; S596-K600 WeakPolarHBondContact O-CG 3.41Å
597A55.9Low69Low41 Ų4176.5 Ų76.534%0.33939%0.387SS..Hα-helixtrans-65.7-50.5170.300000110.2N593 R594 K599 K600N593-A597 PolarHBondContact O-N 3.43Å; R594-A597 PolarHBondContact O-N 2.98Å; A597-K599 VanDerWaalsContact C-N 3.26Å; A597-K599 PolarHBondContact O-N 3.1Å; A597-K600 PolarHBondContact O-N 3.45Å
598T51.2Low67.3Low80 Ų8081.1 Ų81.149%0.49141%0.411SS..Hα-helixtrans-69-12.2-179.144.20000115.7E50 R594 K595E50-T598 VanDerWaalsContact OE2-CA 3.23Å; E50-T598 WeakPolarHBondContact OE2-CA 3.41Å; E50-T598 PolarHBondContact OE2-N 3.29Å; E50-T598 VanDerWaalsContact OE2-N 3.11Å; R594-T598 VanDerWaalsContact O-N 3.13Å; R594-T598 PolarHBondContact O-OG1 3.17Å; R594-T598 PolarHBondContact O-N 2.95Å; K595-T598 VanDerWaalsContact CA-OG1 3.29Å; K595-T598 WeakPolarHBondContact CA-OG1 3.41Å; K595-T598 PolarHBondContact O-OG1 3.25Å; K595-T598 VanDerWaalsContact O-OG1 3.08Å
599K45.3Very low65.4Low173 Ų17386.8 Ų86.875%0.75244%0.441SS*.THydrogen-bonded Turntrans-101.7-7.2177.1-81.6-173.8176.6-174.80114.5K595 A597K595-K599 WeakPolarHBondContact O-CB 3.38Å; K595-K599 WeakPolarHBondContact O-CG 3.41Å; K595-K599 PolarHBondContact O-N 3.36Å; A597-K599 VanDerWaalsContact C-N 3.26Å; A597-K599 PolarHBondContact O-N 3.1Å
600K39.9Very low63.2Low178 Ų17890.4 Ų90.477%0.77445%0.452SS*.  trans-92.63.3-178.2-86.4-177.1175.9-179.70113.8S596 A597S596-K600 WeakPolarHBondContact O-CG 3.41Å; A597-K600 PolarHBondContact O-N 3.45Å
601N37.4Very low60.8Low186 Ų18694.1 Ų94.1100%0.99548%0.475SS*.  trans-124.80167.8-64.9-33.9000109.1

Retrieved 601 of 601 residues in 762.7 ms (Link to these results)