A0A093GZL2_STRCA Loading...

carnitine O-palmitoyltransferase

AlphaFold DB , UniProt , Accession A0A093GZL2, Species STRCA (Struthio camelus australis), Gene n/a, Length 770 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M30.4Very low33.6Very low243 Ų243114 Ų114100%1.19763%0.631SS**  044.10-74.6-156.7-82.800112.7
2A24.6Very low34.5Very low87 Ų87117.8 Ų117.872%0.71964%0.637SS**  trans-116.20.1176.700000113.2
3E26.1Very low35.4Very low167 Ų167114.5 Ų114.578%0.7862%0.624SS**THydrogen-bonded Turntrans-85.5-6.9-176.7-73.4179.1144.100114.2
4A24.8Very low35.9Very low73 Ų73114.4 Ų114.460%0.60363%0.628SS**THydrogen-bonded Turntrans-88.7-14.1-178.200000114.4V8A4-V8 WeakPolarHBondContact O-CG2 3.38Å
5H30.9Very low37.4Very low151 Ų151110.8 Ų110.870%0.69961%0.611SS**G310 helixtrans-87.2-17.9-172.2-83.1-96.4000114.9A7H5-A7 VanDerWaalsContact C-N 3.34Å
6Q31.9Very low38Very low158 Ų158112.4 Ų112.474%0.73863%0.628SS**G310 helixtrans-87.1-0.8178.4-74.5-172.5-11.600114.1
7A32.3Very low38.8Very low81 Ų81115.2 Ų115.267%0.66964%0.642SS**G310 helixtrans-128.834179.100000113.2H5 A9H5-A7 VanDerWaalsContact C-N 3.34Å; A7-A9 VanDerWaalsContact C-N 3.32Å; A7-A9 PolarHBondContact O-N 3.32Å; A7-A9 VanDerWaalsContact O-N 3.08Å
8V37.8Very low39.6Very low62 Ų62110.7 Ų110.738%0.37663%0.625SS.*THydrogen-bonded Turntrans-88.771.3178.8-1650000111.1A4 Q11A4-V8 WeakPolarHBondContact O-CG2 3.38Å; V8-Q11 HydrophobicContact CG1-CB 4.25Å; V8-Q11 HydrophobicContact CG1-CG 3.63Å
9A42.2Very low40.1Very low31 Ų31111.4 Ų111.426%0.25663%0.626SS.*THydrogen-bonded Turntrans-86.6-22158.100000111.6A7 A27A7-A9 VanDerWaalsContact C-N 3.32Å; A7-A9 PolarHBondContact O-N 3.32Å; A7-A9 VanDerWaalsContact O-N 3.08Å; A9-A27 HydrophobicContact CB-CB 3.56Å
10F42.1Very low40.1Very low110 Ų110109.9 Ų109.948%0.48262%0.616SS.*EExtended strand (participates in β ladder)trans-137.8107.7-177.8-60.7-80.5000108.7L21 I31F10-L21 HydrophobicContact CD1-CD2 4.42Å; F10-I31 HydrophobicContact CE2-CD1 3.78Å; F10-I31 HydrophobicContact CZ-CD1 3.45Å; F10-I31 VanDerWaalsContact CZ-CD1 3.45Å
11Q46.1Very low40.4Very low91 Ų91109 Ų10943%0.42561%0.609SS.*EExtended strand (participates in β ladder)trans-91.7117.3162.5-109.1166.14.100106.8V8 R22V8-Q11 HydrophobicContact CG1-CB 4.25Å; V8-Q11 HydrophobicContact CG1-CG 3.63Å; Q11-R22 HydrophobicContact CB-CB 4.45Å; Q11-R22 PolarHBondContact O-N 2.65Å
12F44.4Very low41.3Very low160 Ų160105.7 Ų105.770%0.70258%0.584SS**EExtended strand (participates in β ladder)trans-106.9120.416767.5-87.3000107.8
13T46.9Very low42.6Very low75 Ų75106.6 Ų106.646%0.4657%0.574SS.*EExtended strand (participates in β ladder)trans-118.2116.9172.51.30000106.7T15 D20T13-T15 PolarHBondContact O-N 3.45Å; T13-D20 PolarHBondContact N-O 2.79Å; T13-D20 VanDerWaalsContact N-O 3.14Å; T13-D20 PolarHBondContact O-N 2.96Å
14V41.8Very low44.1Very low113 Ų113101.3 Ų101.369%0.68556%0.556SS**EExtended strand (participates in β ladder)trans-84.3110173.8-176.80000106.7
15T58.9Low45.9Very low60 Ų60105.9 Ų105.937%0.36856%0.564SS.*EExtended strand (participates in β ladder)trans-102.4164173650000109.3T13 D17 G18T13-T15 PolarHBondContact O-N 3.45Å; T15-D17 PolarHBondContact O-N 2.82Å; T15-G18 PolarHBondContact N-O 3.02Å; T15-G18 PolarHBondContact O-N 3.5Å; T15-G18 VanDerWaalsContact O-N 3.14Å; T15-G18 PolarHBondContact OG1-O 3.19Å
16P46.8Very low47.1Very low137 Ų137103 Ų10389%0.8955%0.551SS**THydrogen-bonded Turntrans-56.7-20.2175.8-24.534.7000114
17D51.3Low48.3Very low160 Ų16096.3 Ų96.386%0.85652%0.523SS*.THydrogen-bonded Turntrans-99.3-0.3-177.6-57.9-45.6000114T15T15-D17 PolarHBondContact O-N 2.82Å
18G53.5Low50Low34 Ų3495.6 Ų95.635%0.35151%0.508SS..EExtended strand (participates in β ladder)trans139.2-166.8176.800000115.1T15T15-G18 PolarHBondContact N-O 3.02Å; T15-G18 PolarHBondContact O-N 3.5Å; T15-G18 VanDerWaalsContact O-N 3.14Å; T15-G18 PolarHBondContact OG1-O 3.19Å
19I48.3Very low51.5Low124 Ų12497.6 Ų97.664%0.63651%0.511SS*.EExtended strand (participates in β ladder)trans-92.3111177.4-59.8171.1000108.3L21I19-L21 HydrophobicContact CG2-CD1 4.34Å
20D41.4Very low52.6Low80 Ų8098.8 Ų98.843%0.42851%0.511SS..EExtended strand (participates in β ladder)trans-88.7120.4171.5-170.315.5000109.9T13T13-D20 PolarHBondContact N-O 2.79Å; T13-D20 VanDerWaalsContact N-O 3.14Å; T13-D20 PolarHBondContact O-N 2.96Å
21L47Very low53.9Low91 Ų9197.6 Ų97.648%0.47651%0.509SS..EExtended strand (participates in β ladder)trans-121.691.5-168-141.5153.7000109.2F10 I19 M23F10-L21 HydrophobicContact CD1-CD2 4.42Å; I19-L21 HydrophobicContact CG2-CD1 4.34Å; L21-M23 HydrophobicContact CD2-CG 3.47Å; L21-M23 VanDerWaalsContact CD2-CG 3.47Å; L21-M23 HydrophobicContact CD2-SD 4.18Å; L21-M23 PolarHBondContact O-N 3.34Å
22R48.7Very low55.2Low175 Ų175100.9 Ų100.966%0.6652%0.519SS*.EExtended strand (participates in β ladder)trans-81.299.1175-77-172.1175.5-171.7-1.9110.1Q11Q11-R22 HydrophobicContact CB-CB 4.45Å; Q11-R22 PolarHBondContact O-N 2.65Å
23M50.8Low56.5Low106 Ų10695.5 Ų95.552%0.52250%0.497SS..EExtended strand (participates in β ladder)trans-87.5121.1175.6-64.7-168.4-68.400111.1L21 H25 L28L21-M23 HydrophobicContact CD2-CG 3.47Å; L21-M23 VanDerWaalsContact CD2-CG 3.47Å; L21-M23 HydrophobicContact CD2-SD 4.18Å; L21-M23 PolarHBondContact O-N 3.34Å; M23-H25 PolarHBondContact O-N 2.95Å; M23-L28 HydrophobicContact CB-CD1 3.95Å; M23-L28 HydrophobicContact CB-CG 4.42Å; M23-L28 HydrophobicContact CE-CD1 4.3Å; M23-L28 HydrophobicContact SD-CD1 4.11Å; M23-L28 HydrophobicContact SD-CD2 4.13Å
24S57.6Low57.4Low56 Ų5694.2 Ų94.239%0.39249%0.491SS..  trans-72.4123.5170.9170.80000110.2E26 A27 L28S24-E26 PolarHBondContact O-N 3.07Å; S24-E26 PolarHBondContact OG-N 2.64Å; S24-A27 WeakPolarHBondContact O-CB 3.48Å; S24-A27 PolarHBondContact O-N 3.23Å; S24-L28 PolarHBondContact O-N 2.7Å
25H62.3Low58.8Low169 Ų16990.7 Ų90.778%0.78248%0.478SS*.Hα-helixtrans-54.6-37.1175.8-96.4-68.9000112.5M23 L28 K29M23-H25 PolarHBondContact O-N 2.95Å; H25-L28 PolarHBondContact O-N 3.08Å; H25-K29 WeakPolarHBondContact O-CB 3.33Å; H25-K29 PolarHBondContact O-N 3.15Å
26E56.9Low59.6Low91 Ų9189.6 Ų89.643%0.42547%0.471SS..Hα-helixtrans-69.9-38.2178.3-161.960.6-145.400111S24 K29 Q30S24-E26 PolarHBondContact O-N 3.07Å; S24-E26 PolarHBondContact OG-N 2.64Å; E26-K29 WeakPolarHBondContact O-CB 3.48Å; E26-K29 PolarHBondContact O-N 2.79Å; E26-K29 IonicContact OE1-NZ 2.86Å; E26-K29 PolarHBondContact OE1-NZ 3.42Å; E26-K29 IonicContact OE2-NZ 3.41Å; E26-K29 PolarHBondContact OE2-NZ 2.75Å; E26-Q30 VanDerWaalsContact O-CG 3.28Å; E26-Q30 WeakPolarHBondContact O-CG 3.05Å; E26-Q30 PolarHBondContact O-N 2.85Å
27A56.5Low60.8Low17 Ų1787 Ų8714%0.1445%0.447CS..Hα-helixtrans-64.3-43.3175.200000112.3A9 S24 K29 Q30 I31A9-A27 HydrophobicContact CB-CB 3.56Å; S24-A27 WeakPolarHBondContact O-CB 3.48Å; S24-A27 PolarHBondContact O-N 3.23Å; A27-K29 VanDerWaalsContact C-N 3.34Å; A27-K29 PolarHBondContact O-N 3.47Å; A27-Q30 PolarHBondContact O-N 3.15Å; A27-I31 VanDerWaalsContact O-CG1 3.29Å; A27-I31 WeakPolarHBondContact O-CG1 3.38Å; A27-I31 PolarHBondContact O-N 3.42Å
28L68.1Low61.8Low66 Ų6681.7 Ų81.735%0.34642%0.422SS..Hα-helixtrans-61.6-41.8174.8-74.2172.8000111.8M23 S24 H25 I31 Y32M23-L28 HydrophobicContact CB-CD1 3.95Å; M23-L28 HydrophobicContact CB-CG 4.42Å; M23-L28 HydrophobicContact CE-CD1 4.3Å; M23-L28 HydrophobicContact SD-CD1 4.11Å; M23-L28 HydrophobicContact SD-CD2 4.13Å; S24-L28 PolarHBondContact O-N 2.7Å; H25-L28 PolarHBondContact O-N 3.08Å; L28-I31 PolarHBondContact O-N 2.98Å; L28-Y32 WeakPolarHBondContact O-CB 3.2Å; L28-Y32 PolarHBondContact O-N 2.97Å
29K70.8Confident63.1Low104 Ų10488.4 Ų88.445%0.45244%0.437SS..Hα-helixtrans-61-42.9174.2178.4-178.9160.5-146.30111.7H25 E26 A27 Y32 L33H25-K29 WeakPolarHBondContact O-CB 3.33Å; H25-K29 PolarHBondContact O-N 3.15Å; E26-K29 WeakPolarHBondContact O-CB 3.48Å; E26-K29 PolarHBondContact O-N 2.79Å; E26-K29 IonicContact OE1-NZ 2.86Å; E26-K29 PolarHBondContact OE1-NZ 3.42Å; E26-K29 IonicContact OE2-NZ 3.41Å; E26-K29 PolarHBondContact OE2-NZ 2.75Å; A27-K29 VanDerWaalsContact C-N 3.34Å; A27-K29 PolarHBondContact O-N 3.47Å; K29-Y32 PolarHBondContact O-N 2.88Å; K29-L33 HydrophobicContact CG-CD1 4.15Å; K29-L33 WeakPolarHBondContact O-CB 3.33Å; K29-L33 VanDerWaalsContact O-CG 3.28Å; K29-L33 WeakPolarHBondContact O-CG 2.98Å; K29-L33 PolarHBondContact O-N 2.84Å
30Q63.6Low64.6Low55 Ų5587.7 Ų87.726%0.25743%0.429SS..Hα-helixtrans-66.5-39.7176.4-67.5-60.9-30.300112.5E26 A27 L33 S34 D350E26-Q30 VanDerWaalsContact O-CG 3.28Å; E26-Q30 WeakPolarHBondContact O-CG 3.05Å; E26-Q30 PolarHBondContact O-N 2.85Å; A27-Q30 PolarHBondContact O-N 3.15Å; Q30-L33 PolarHBondContact O-N 3.16Å; Q30-S34 WeakPolarHBondContact O-CB 3.49Å; Q30-S34 PolarHBondContact O-N 3.42Å; Q30-D350 PolarHBondContact NE2-OD1 3.28Å
31I69.3Low66.3Low86 Ų8686.5 Ų86.544%0.44142%0.42SS..Hα-helixtrans-62.6-46.7174.1-69.1167.2000110.2F10 A27 L28 S34 G35F10-I31 HydrophobicContact CE2-CD1 3.78Å; F10-I31 HydrophobicContact CZ-CD1 3.45Å; F10-I31 VanDerWaalsContact CZ-CD1 3.45Å; A27-I31 VanDerWaalsContact O-CG1 3.29Å; A27-I31 WeakPolarHBondContact O-CG1 3.38Å; A27-I31 PolarHBondContact O-N 3.42Å; L28-I31 PolarHBondContact O-N 2.98Å; I31-S34 PolarHBondContact O-N 3.22Å; I31-G35 PolarHBondContact O-N 2.73Å
32Y74.6Confident67.9Low159 Ų15988.1 Ų88.162%0.62442%0.424SS*.Hα-helixtrans-59.1-51.5176173-103.2000111.6L28 K29 S34 G35 V36L28-Y32 WeakPolarHBondContact O-CB 3.2Å; L28-Y32 PolarHBondContact O-N 2.97Å; K29-Y32 PolarHBondContact O-N 2.88Å; Y32-S34 VanDerWaalsContact C-N 3.35Å; Y32-S34 PolarHBondContact O-N 2.93Å; Y32-G35 WeakPolarHBondContact O-CA 3.35Å; Y32-G35 PolarHBondContact O-N 3.09Å; Y32-G35 VanDerWaalsContact O-N 3.12Å; Y32-V36 HydrophobicContact CD1-CG2 4.34Å; Y32-V36 HydrophobicContact CD2-CG2 4.22Å; Y32-V36 HydrophobicContact CE1-CG2 3.92Å; Y32-V36 HydrophobicContact CE2-CG2 3.78Å; Y32-V36 HydrophobicContact CG-CG2 4.48Å; Y32-V36 WeakPolarHBondContact O-CG2 3.43Å; Y32-V36 PolarHBondContact O-N 2.84Å
33L71.3Confident69.6Low47 Ų4784.8 Ų84.825%0.24641%0.414CS..Hα-helixtrans-60.5-43178.5-72.4174.3000111.8K29 Q30 G35 V36 H37K29-L33 HydrophobicContact CG-CD1 4.15Å; K29-L33 WeakPolarHBondContact O-CB 3.33Å; K29-L33 VanDerWaalsContact O-CG 3.28Å; K29-L33 WeakPolarHBondContact O-CG 2.98Å; K29-L33 PolarHBondContact O-N 2.84Å; Q30-L33 PolarHBondContact O-N 3.16Å; L33-G35 VanDerWaalsContact C-N 3.34Å; L33-V36 PolarHBondContact O-N 2.73Å; L33-H37 WeakPolarHBondContact O-CB 3.47Å; L33-H37 PolarHBondContact O-N 3.48Å; L33-H37 PolarHBondContact O-ND1 3.15Å
34S65.7Low71.2Confident48 Ų4882 Ų8234%0.33640%0.401SS..Hα-helixtrans-61.3-42174.4-179.70000111.5Q30 I31 Y32 H37 S38 K332Q30-S34 WeakPolarHBondContact O-CB 3.49Å; Q30-S34 PolarHBondContact O-N 3.42Å; I31-S34 PolarHBondContact O-N 3.22Å; Y32-S34 VanDerWaalsContact C-N 3.35Å; Y32-S34 PolarHBondContact O-N 2.93Å; S34-H37 PolarHBondContact O-N 2.97Å; S34-S38 VanDerWaalsContact O-CB 3.28Å; S34-S38 WeakPolarHBondContact O-CB 3.32Å; S34-S38 PolarHBondContact O-N 3.3Å; S34-K332 PolarHBondContact OG-NZ 3.34Å
35G71.4Confident72.4Confident40 Ų4082.7 Ų82.741%0.41240%0.395SS..Hα-helixtrans-61-49.7174.700000112.4I31 Y32 L33 H37 S38 W39I31-G35 PolarHBondContact O-N 2.73Å; Y32-G35 WeakPolarHBondContact O-CA 3.35Å; Y32-G35 PolarHBondContact O-N 3.09Å; Y32-G35 VanDerWaalsContact O-N 3.12Å; L33-G35 VanDerWaalsContact C-N 3.34Å; G35-H37 PolarHBondContact O-N 3.42Å; G35-S38 PolarHBondContact O-N 3.32Å; G35-W39 WeakPolarHBondContact O-CB 3.26Å; G35-W39 PolarHBondContact O-N 2.83Å
36V76.6Confident73.4Confident36 Ų3681.2 Ų81.222%0.21839%0.387CS..Hα-helixtrans-59.7-44.4176.9171.40000111.2Y32 L33 W39 K40Y32-V36 HydrophobicContact CD1-CG2 4.34Å; Y32-V36 HydrophobicContact CD2-CG2 4.22Å; Y32-V36 HydrophobicContact CE1-CG2 3.92Å; Y32-V36 HydrophobicContact CE2-CG2 3.78Å; Y32-V36 HydrophobicContact CG-CG2 4.48Å; Y32-V36 WeakPolarHBondContact O-CG2 3.43Å; Y32-V36 PolarHBondContact O-N 2.84Å; L33-V36 PolarHBondContact O-N 2.73Å; V36-W39 PolarHBondContact O-N 3.2Å; V36-K40 HydrophobicContact CG1-CD 4.15Å; V36-K40 HydrophobicContact CG1-CG 4.46Å; V36-K40 WeakPolarHBondContact O-CB 3.3Å; V36-K40 WeakPolarHBondContact O-CG 3.49Å; V36-K40 PolarHBondContact O-N 3.49Å
37H71Confident74.9Confident83 Ų8382 Ų8238%0.38439%0.388SS..Hα-helixtrans-67.1-42.3178.4-78.287.1000112.4L33 S34 G35 W39 K40 K41 G351L33-H37 WeakPolarHBondContact O-CB 3.47Å; L33-H37 PolarHBondContact O-N 3.48Å; L33-H37 PolarHBondContact O-ND1 3.15Å; S34-H37 PolarHBondContact O-N 2.97Å; G35-H37 PolarHBondContact O-N 3.42Å; H37-W39 VanDerWaalsContact C-N 3.33Å; H37-W39 PolarHBondContact O-N 3.47Å; H37-K40 PolarHBondContact O-N 3.11Å; H37-K41 WeakPolarHBondContact O-CB 3.34Å; H37-K41 PolarHBondContact O-N 3.49Å; H37-G351 PolarHBondContact CD2-O 3.48Å; H37-G351 PolarHBondContact NE2-O 2.85Å
38S72.1Confident76.4Confident48 Ų4881.7 Ų81.734%0.33638%0.384SS..Hα-helixtrans-59.3-45.9174.4-174.80000110.7S34 G35 K41 K42S34-S38 VanDerWaalsContact O-CB 3.28Å; S34-S38 WeakPolarHBondContact O-CB 3.32Å; S34-S38 PolarHBondContact O-N 3.3Å; G35-S38 PolarHBondContact O-N 3.32Å; S38-K41 PolarHBondContact O-N 2.89Å; S38-K42 WeakPolarHBondContact O-CB 3.45Å; S38-K42 WeakPolarHBondContact O-CG 3.32Å; S38-K42 PolarHBondContact O-N 2.89Å
39W80.8Confident77.3Confident175 Ų17580.3 Ų80.366%0.66339%0.386SS*.Hα-helixtrans-63.6-46.4176.4-173.883.2000112.2G35 V36 H37 K41 K42 F43G35-W39 WeakPolarHBondContact O-CB 3.26Å; G35-W39 PolarHBondContact O-N 2.83Å; V36-W39 PolarHBondContact O-N 3.2Å; H37-W39 VanDerWaalsContact C-N 3.33Å; H37-W39 PolarHBondContact O-N 3.47Å; W39-K41 VanDerWaalsContact C-N 3.32Å; W39-K41 PolarHBondContact O-N 3.09Å; W39-K42 PolarHBondContact O-N 3.16Å; W39-F43 VanDerWaalsContact O-CB 3.31Å; W39-F43 WeakPolarHBondContact O-CB 3.15Å; W39-F43 PolarHBondContact O-N 3.41Å
40K81.1Confident78Confident110 Ų11078.8 Ų78.848%0.47838%0.382SS..Hα-helixtrans-56.7-44.4173.9-77.6178.3179.9178.70111.8V36 H37 F43 I44V36-K40 HydrophobicContact CG1-CD 4.15Å; V36-K40 HydrophobicContact CG1-CG 4.46Å; V36-K40 WeakPolarHBondContact O-CB 3.3Å; V36-K40 WeakPolarHBondContact O-CG 3.49Å; V36-K40 PolarHBondContact O-N 3.49Å; H37-K40 PolarHBondContact O-N 3.11Å; K40-F43 PolarHBondContact O-N 3.38Å; K40-I44 VanDerWaalsContact O-CG1 3.26Å; K40-I44 WeakPolarHBondContact O-CG1 3.3Å; K40-I44 PolarHBondContact O-N 3.44Å
41K75.8Confident79Confident54 Ų5478.5 Ų78.524%0.23538%0.382CS..Hα-helixtrans-64-47.3177.9-169.3-176.4-170.6-171.20111.4H37 S38 W39 F43 I44 R45 D287 D330H37-K41 WeakPolarHBondContact O-CB 3.34Å; H37-K41 PolarHBondContact O-N 3.49Å; S38-K41 PolarHBondContact O-N 2.89Å; W39-K41 VanDerWaalsContact C-N 3.32Å; W39-K41 PolarHBondContact O-N 3.09Å; K41-F43 VanDerWaalsContact C-N 3.34Å; K41-F43 PolarHBondContact O-N 2.82Å; K41-I44 PolarHBondContact O-N 3.39Å; K41-R45 VanDerWaalsContact CE-CZ 3.44Å; K41-R45 WeakPolarHBondContact O-CG 3.36Å; K41-R45 PolarHBondContact O-N 2.73Å; K41-D287 WeakPolarHBondContact CE-OD2 3.46Å; K41-D287 IonicContact NZ-OD1 3.84Å; K41-D287 IonicContact NZ-OD2 2.96Å; K41-D287 PolarHBondContact NZ-OD2 3.16Å; K41-D330 IonicContact NZ-OD1 3.74Å; K41-D330 PolarHBondContact NZ-OD1 3.37Å
42K81.1Confident79.9Confident126 Ų12675.2 Ų75.255%0.54837%0.366SS..Hα-helixtrans-60.2-43.5176.1-74179.1-177.6-175.90111.4S38 W39 R45 F46S38-K42 WeakPolarHBondContact O-CB 3.45Å; S38-K42 WeakPolarHBondContact O-CG 3.32Å; S38-K42 PolarHBondContact O-N 2.89Å; W39-K42 PolarHBondContact O-N 3.16Å; K42-R45 PolarHBondContact O-N 2.74Å; K42-F46 WeakPolarHBondContact O-CB 3.28Å; K42-F46 PolarHBondContact O-N 2.73Å
43F85.3Confident80.3Confident104 Ų10469.3 Ų69.346%0.45635%0.354SS..Hα-helixtrans-63.4-45.1176.5179.6-99.3000112.1W39 K40 K41 R45 F46 K47W39-F43 VanDerWaalsContact O-CB 3.31Å; W39-F43 WeakPolarHBondContact O-CB 3.15Å; W39-F43 PolarHBondContact O-N 3.41Å; K40-F43 PolarHBondContact O-N 3.38Å; K41-F43 VanDerWaalsContact C-N 3.34Å; K41-F43 PolarHBondContact O-N 2.82Å; F43-R45 PolarHBondContact O-N 3.47Å; F43-F46 PolarHBondContact O-N 2.89Å; F43-K47 HydrophobicContact CE1-CD 4.45Å; F43-K47 VanDerWaalsContact O-CB 3.24Å; F43-K47 WeakPolarHBondContact O-CB 3.39Å; F43-K47 PolarHBondContact O-N 3.41Å
44I83.9Confident81.1Confident49 Ų4968 Ų6825%0.25135%0.348SS..Hα-helixtrans-60.4-46.5175.2-70.1165.2000110.4K40 K41 F46 K47 N48 R288K40-I44 VanDerWaalsContact O-CG1 3.26Å; K40-I44 WeakPolarHBondContact O-CG1 3.3Å; K40-I44 PolarHBondContact O-N 3.44Å; K41-I44 PolarHBondContact O-N 3.39Å; I44-F46 PolarHBondContact O-N 3.44Å; I44-K47 PolarHBondContact O-N 3.14Å; I44-N48 VanDerWaalsContact O-CB 3.24Å; I44-N48 WeakPolarHBondContact O-CB 3.48Å; I44-N48 PolarHBondContact O-N 3.42Å; I44-N48 PolarHBondContact O-ND2 3.14Å; I44-N48 PolarHBondContact O-OD1 3.1Å; I44-R288 HydrophobicContact CG2-CG 4.27Å
45R81.8Confident82.2Confident70 Ų7066.1 Ų66.126%0.26433%0.333SS..Hα-helixtrans-61-43.4176.9-75.2178.8174.5165.7-8112K41 K42 F43 N48 G49 D287 K329 D330K41-R45 VanDerWaalsContact CE-CZ 3.44Å; K41-R45 WeakPolarHBondContact O-CG 3.36Å; K41-R45 PolarHBondContact O-N 2.73Å; K42-R45 PolarHBondContact O-N 2.74Å; F43-R45 PolarHBondContact O-N 3.47Å; R45-N48 PolarHBondContact O-N 2.92Å; R45-G49 PolarHBondContact O-N 2.99Å; R45-D287 IonicContact CZ-OD1 3.07Å; R45-D287 IonicContact NE-OD1 3.24Å; R45-D287 IonicContact NH2-OD1 2.77Å; R45-D287 PolarHBondContact NH2-OD1 3.32Å; R45-D287 IonicContact NH2-OD2 3.32Å; R45-K329 PolarHBondContact NH1-O 2.7Å; R45-K329 PolarHBondContact NH2-O 3.48Å; R45-D330 IonicContact CZ-OD1 3.63Å; R45-D330 IonicContact NH1-OD1 3.88Å; R45-D330 PolarHBondContact NH1-OD1 2.99Å; R45-D330 IonicContact NH1-OD2 3.77Å; R45-D330 PolarHBondContact NH1-OD2 3.09Å; R45-D330 IonicContact NH2-OD1 3.95Å; R45-D330 PolarHBondContact NH2-OD1 3.2Å
46F84.4Confident83Confident138 Ų13864.6 Ų64.661%0.60532%0.316SS*.Hα-helixtrans-62.5-50.9176174.6-103.4000111.8K42 F43 I44 N48 G49 I50K42-F46 WeakPolarHBondContact O-CB 3.28Å; K42-F46 PolarHBondContact O-N 2.73Å; F43-F46 PolarHBondContact O-N 2.89Å; I44-F46 PolarHBondContact O-N 3.44Å; F46-N48 VanDerWaalsContact C-N 3.34Å; F46-N48 PolarHBondContact O-N 3.5Å; F46-G49 PolarHBondContact O-N 3.37Å; F46-G49 VanDerWaalsContact O-N 3.17Å; F46-I50 HydrophobicContact CD1-CD1 4.01Å; F46-I50 HydrophobicContact CE1-CD1 3.41Å; F46-I50 VanDerWaalsContact CE1-CD1 3.41Å; F46-I50 HydrophobicContact CE1-CG1 4.5Å; F46-I50 HydrophobicContact CE2-CD1 4.14Å; F46-I50 HydrophobicContact CZ-CD1 3.5Å; F46-I50 HydrophobicContact CZ-CG1 4.38Å; F46-I50 PolarHBondContact O-N 2.95Å
47K88.7Confident83.5Confident106 Ų10663.8 Ų63.846%0.46131%0.313SS..Hα-helixtrans-55-49.3175.1174.9-174.2171.1-178.80111F43 I44 G49 I50 I51F43-K47 HydrophobicContact CE1-CD 4.45Å; F43-K47 VanDerWaalsContact O-CB 3.24Å; F43-K47 WeakPolarHBondContact O-CB 3.39Å; F43-K47 PolarHBondContact O-N 3.41Å; I44-K47 PolarHBondContact O-N 3.14Å; K47-G49 VanDerWaalsContact C-N 3.33Å; K47-G49 PolarHBondContact O-N 3.07Å; K47-I50 PolarHBondContact O-N 3.39Å; K47-I51 HydrophobicContact CD-CD1 4.37Å; K47-I51 HydrophobicContact CG-CD1 3.8Å; K47-I51 HydrophobicContact CG-CG1 4.49Å; K47-I51 VanDerWaalsContact O-CG1 3.31Å; K47-I51 WeakPolarHBondContact O-CG1 3.44Å; K47-I51 PolarHBondContact O-N 2.77Å
48N88.1Confident84.3Confident11 Ų1161.9 Ų61.96%0.05931%0.309CS..Hα-helixtrans-63.1-42.1179-69.7-5.3000110.8I44 R45 F46 I50 I51 T52 M163 R288I44-N48 VanDerWaalsContact O-CB 3.24Å; I44-N48 WeakPolarHBondContact O-CB 3.48Å; I44-N48 PolarHBondContact O-N 3.42Å; I44-N48 PolarHBondContact O-ND2 3.14Å; I44-N48 PolarHBondContact O-OD1 3.1Å; R45-N48 PolarHBondContact O-N 2.92Å; F46-N48 VanDerWaalsContact C-N 3.34Å; F46-N48 PolarHBondContact O-N 3.5Å; N48-I50 VanDerWaalsContact C-N 3.3Å; N48-I50 PolarHBondContact O-N 2.92Å; N48-I51 PolarHBondContact O-N 2.6Å; N48-I51 VanDerWaalsContact O-N 3.12Å; N48-T52 PolarHBondContact O-N 3.49Å; N48-T52 PolarHBondContact O-OG1 2.99Å; N48-M163 HydrophobicContact CB-CE 3.91Å; N48-M163 HydrophobicContact CB-SD 4.42Å; N48-M163 WeakPolarHBondContact ND2-CE 3.25Å; N48-M163 VanDerWaalsContact OD1-CE 3.32Å; N48-M163 WeakPolarHBondContact OD1-CE 3.41Å; N48-R288 PolarHBondContact ND2-O 2.94Å
49G85.3Confident85Confident37 Ų3762.5 Ų62.538%0.38131%0.312SS..Hα-helixtrans-57.3-40.4174.100000112.9R45 F46 K47 T52 G53R45-G49 PolarHBondContact O-N 2.99Å; F46-G49 PolarHBondContact O-N 3.37Å; F46-G49 VanDerWaalsContact O-N 3.17Å; K47-G49 VanDerWaalsContact C-N 3.33Å; K47-G49 PolarHBondContact O-N 3.07Å; G49-T52 PolarHBondContact O-OG1 3.41Å; G49-G53 VanDerWaalsContact O-CA 3.29Å; G49-G53 WeakPolarHBondContact O-CA 3.45Å; G49-G53 PolarHBondContact O-N 3.46Å
50I85.4Confident85.3Confident73 Ų7357.9 Ų57.937%0.37431%0.306SS..Hα-helixtrans-65.2-50.7171.7-66.4172.3000110.4F46 K47 N48 T52 G53 V54 P59F46-I50 HydrophobicContact CD1-CD1 4.01Å; F46-I50 HydrophobicContact CE1-CD1 3.41Å; F46-I50 VanDerWaalsContact CE1-CD1 3.41Å; F46-I50 HydrophobicContact CE1-CG1 4.5Å; F46-I50 HydrophobicContact CE2-CD1 4.14Å; F46-I50 HydrophobicContact CZ-CD1 3.5Å; F46-I50 HydrophobicContact CZ-CG1 4.38Å; F46-I50 PolarHBondContact O-N 2.95Å; K47-I50 PolarHBondContact O-N 3.39Å; N48-I50 VanDerWaalsContact C-N 3.3Å; N48-I50 PolarHBondContact O-N 2.92Å; I50-T52 PolarHBondContact O-N 3.2Å; I50-G53 CarbonylContact O-C 3.21Å; I50-G53 PolarHBondContact O-N 3.02Å; I50-G53 VanDerWaalsContact O-N 3.13Å; I50-V54 WeakPolarHBondContact O-CG1 3.27Å; I50-V54 WeakPolarHBondContact O-CG2 3.33Å; I50-V54 PolarHBondContact O-N 3.08Å; I50-P59 HydrophobicContact CG2-CG 4.3Å
51I86.5Confident85.7Confident48 Ų4854 Ų5425%0.24629%0.293CS..Hα-helixtrans-58.5-48.9-177.4-68.9168.2000111.2K47 N48 G53 Y55 P59 M163K47-I51 HydrophobicContact CD-CD1 4.37Å; K47-I51 HydrophobicContact CG-CD1 3.8Å; K47-I51 HydrophobicContact CG-CG1 4.49Å; K47-I51 VanDerWaalsContact O-CG1 3.31Å; K47-I51 WeakPolarHBondContact O-CG1 3.44Å; K47-I51 PolarHBondContact O-N 2.77Å; N48-I51 PolarHBondContact O-N 2.6Å; N48-I51 VanDerWaalsContact O-N 3.12Å; I51-G53 VanDerWaalsContact C-N 3.34Å; I51-Y55 PolarHBondContact O-N 3.34Å; I51-P59 HydrophobicContact CG1-CG 4.4Å; I51-M163 HydrophobicContact CB-SD 4.21Å; I51-M163 HydrophobicContact CG2-SD 3.73Å
52T86.3Confident86.6Confident17 Ų1755.7 Ų55.710%0.10430%0.298CS..Hα-helixtrans-69.9-34.8176.2560000111.6N48 G49 I50 V54 Y55 M163 Q289N48-T52 PolarHBondContact O-N 3.49Å; N48-T52 PolarHBondContact O-OG1 2.99Å; G49-T52 PolarHBondContact O-OG1 3.41Å; I50-T52 PolarHBondContact O-N 3.2Å; T52-V54 PolarHBondContact O-N 3.43Å; T52-Y55 WeakPolarHBondContact O-CB 3.46Å; T52-Y55 PolarHBondContact O-N 3.35Å; T52-M163 HydrophobicContact CG2-CB 4.01Å; T52-M163 HydrophobicContact CG2-SD 4.27Å; T52-Q289 VanDerWaalsContact CG2-OE1 3.27Å
53G83.8Confident87Confident36 Ų3654.4 Ų54.437%0.37130%0.297SS..Hα-helixtrans-66.3-22.6179.300000114.1G49 I50 I51 R123G49-G53 VanDerWaalsContact O-CA 3.29Å; G49-G53 WeakPolarHBondContact O-CA 3.45Å; G49-G53 PolarHBondContact O-N 3.46Å; I50-G53 CarbonylContact O-C 3.21Å; I50-G53 PolarHBondContact O-N 3.02Å; I50-G53 VanDerWaalsContact O-N 3.13Å; I51-G53 VanDerWaalsContact C-N 3.34Å; G53-R123 PolarHBondContact O-NH2 3.34Å
54V87.9Confident87.3Confident19 Ų1955.2 Ų55.212%0.11531%0.305CS..Hα-helixtrans-107-2.1177.3-54.30000113.3I50 T52 A57 P59 W115 I119I50-V54 WeakPolarHBondContact O-CG1 3.27Å; I50-V54 WeakPolarHBondContact O-CG2 3.33Å; I50-V54 PolarHBondContact O-N 3.08Å; T52-V54 PolarHBondContact O-N 3.43Å; V54-A57 WeakPolarHBondContact O-CA 3.5Å; V54-A57 WeakPolarHBondContact O-CB 3.4Å; V54-A57 PolarHBondContact O-N 3.33Å; V54-P59 HydrophobicContact CG2-CG 4.27Å; V54-W115 HydrophobicContact CB-CH2 4.06Å; V54-W115 HydrophobicContact CB-CZ2 4.19Å; V54-W115 HydrophobicContact CG1-CH2 3.62Å; V54-W115 HydrophobicContact CG1-CZ2 4.25Å; V54-W115 HydrophobicContact CG1-CZ3 4.46Å; V54-I119 HydrophobicContact CB-CD1 3.96Å; V54-I119 HydrophobicContact CG1-CD1 4.42Å
55Y89.5Confident87.7Confident8 Ų854.3 Ų54.33%0.03130%0.301CS..THydrogen-bonded Turntrans-59.4139.9175.2-170-89.9000110.4I51 T52 R123 L126 G159 P162 S166 F167I51-Y55 PolarHBondContact O-N 3.34Å; T52-Y55 WeakPolarHBondContact O-CB 3.46Å; T52-Y55 PolarHBondContact O-N 3.35Å; Y55-R123 PolarHBondContact O-NH2 3.33Å; Y55-L126 HydrophobicContact CE1-CD2 4.46Å; Y55-G159 PolarHBondContact OH-N 3.04Å; Y55-G159 PolarHBondContact OH-O 3.01Å; Y55-G159 VanDerWaalsContact OH-O 3.06Å; Y55-P162 HydrophobicContact CE2-CB 4.12Å; Y55-S166 WeakPolarHBondContact CD1-O 3.35Å; Y55-F167 AromaticContact CE1-CD1 3.73Å; Y55-F167 HydrophobicContact CE1-CD1 3.73Å; Y55-F167 AromaticContact CE1-CE1 3.6Å; Y55-F167 HydrophobicContact CE1-CE1 3.6Å; Y55-F167 HydrophobicContact CE1-CG 4.32Å; Y55-F167 HydrophobicContact CE1-CZ 4.09Å; Y55-F167 AromaticContact CZ-CE1 3.88Å; Y55-F167 AromaticContact CZ-CZ 3.93Å; Y55-F167 WeakPolarHBondContact OH-CE1 3.34Å; Y55-F167 WeakPolarHBondContact OH-CZ 3.3Å
56P87.9Confident88.2Confident9 Ų951.5 Ų51.56%0.05829%0.292CS..THydrogen-bonded Turncis-81.6-1.311.533.4-37.4000116.9M122 F157P56-M122 HydrophobicContact CB-CE 4.37Å; P56-M122 HydrophobicContact CG-CB 3.73Å; P56-M122 HydrophobicContact CG-CE 3.92Å; P56-F157 WeakPolarHBondContact CB-O 3.38Å; P56-F157 WeakPolarHBondContact CG-O 3.45Å
57A87.7Confident88.6Confident19 Ų1948.5 Ų48.516%0.15729%0.285CS..SBendtrans-80.1-171174.700000111.9V54 I119V54-A57 WeakPolarHBondContact O-CA 3.5Å; V54-A57 WeakPolarHBondContact O-CB 3.4Å; V54-A57 PolarHBondContact O-N 3.33Å; A57-I119 HydrophobicContact CB-CD1 3.94Å; A57-I119 HydrophobicContact CB-CG1 3.51Å
58S87.3Confident88.8Confident43 Ų4345.1 Ų45.130%0.30128%0.28SS..  trans-138.5155.2178.762.50000110.8S60 S61S58-S60 WeakPolarHBondContact CB-OG 3.28Å; S58-S60 PolarHBondContact O-N 2.87Å; S58-S60 VanDerWaalsContact O-N 3.16Å; S58-S60 PolarHBondContact OG-OG 2.82Å; S58-S61 PolarHBondContact N-OG 3.43Å; S58-S61 PolarHBondContact O-N 3.5Å; S58-S61 PolarHBondContact O-OG 3.47Å; S58-S61 PolarHBondContact OG-N 2.9Å
59P86.1Confident88.9Confident60 Ų6045 Ų4539%0.3928%0.279SS..Hα-helixtrans-55.3-31.3171.7-26.936000113.1I50 I51 V54 S61 W62I50-P59 HydrophobicContact CG2-CG 4.3Å; I51-P59 HydrophobicContact CG1-CG 4.4Å; V54-P59 HydrophobicContact CG2-CG 4.27Å; P59-S61 VanDerWaalsContact C-N 3.33Å; P59-S61 PolarHBondContact O-N 3.37Å; P59-W62 WeakPolarHBondContact O-CB 3.49Å; P59-W62 PolarHBondContact O-N 2.9Å
60S87.8Confident89.1Confident78 Ų7845.7 Ų45.755%0.54527%0.273SS..Hα-helixtrans-66.2-29.5173.938.70000113.8S58 W62 L63 I64S58-S60 WeakPolarHBondContact CB-OG 3.28Å; S58-S60 PolarHBondContact O-N 2.87Å; S58-S60 VanDerWaalsContact O-N 3.16Å; S58-S60 PolarHBondContact OG-OG 2.82Å; S60-W62 VanDerWaalsContact C-N 3.26Å; S60-W62 PolarHBondContact O-N 2.91Å; S60-L63 PolarHBondContact O-N 2.85Å; S60-I64 PolarHBondContact O-N 3.34Å
61S90Very high89.3Confident29 Ų2945.5 Ų45.520%0.20328%0.279CS..Hα-helixtrans-72.3-22.2177.4700000112.6S58 P59 I64 V65 W115S58-S61 PolarHBondContact N-OG 3.43Å; S58-S61 PolarHBondContact O-N 3.5Å; S58-S61 PolarHBondContact O-OG 3.47Å; S58-S61 PolarHBondContact OG-N 2.9Å; P59-S61 VanDerWaalsContact C-N 3.33Å; P59-S61 PolarHBondContact O-N 3.37Å; S61-I64 PolarHBondContact O-N 3.04Å; S61-V65 WeakPolarHBondContact O-CG2 3.39Å; S61-V65 PolarHBondContact O-N 3.03Å; S61-W115 PolarHBondContact OG-NE1 3.46Å
62W92.8Very high89.5Confident89 Ų8945.2 Ų45.234%0.33728%0.279SS..Hα-helixtrans-61.4-47.3170.3172.579.2000110.7P59 S60 I64 V65 V66 I108 T112 W115P59-W62 WeakPolarHBondContact O-CB 3.49Å; P59-W62 PolarHBondContact O-N 2.9Å; S60-W62 VanDerWaalsContact C-N 3.26Å; S60-W62 PolarHBondContact O-N 2.91Å; W62-I64 VanDerWaalsContact C-N 3.29Å; W62-I64 PolarHBondContact O-N 3.38Å; W62-V65 PolarHBondContact O-N 3.49Å; W62-V66 HydrophobicContact CD2-CG2 4.13Å; W62-V66 HydrophobicContact CG-CG2 4.38Å; W62-V66 HydrophobicContact CZ2-CG2 3.94Å; W62-V66 WeakPolarHBondContact O-CG2 3.4Å; W62-V66 PolarHBondContact O-N 3.47Å; W62-I108 HydrophobicContact CZ2-CG2 4.42Å; W62-T112 PolarHBondContact NE1-OG1 3.16Å; W62-W115 VanDerWaalsContact CA-CD1 3.47Å; W62-W115 HydrophobicContact CB-CD2 3.72Å; W62-W115 HydrophobicContact CB-CE3 4.22Å; W62-W115 HydrophobicContact CB-CG 4.05Å; W62-W115 HydrophobicContact CB-CH2 4.25Å; W62-W115 HydrophobicContact CB-CZ2 3.78Å; W62-W115 HydrophobicContact CB-CZ3 4.47Å; W62-W115 AromaticContact CD1-CD2 3.81Å; W62-W115 AromaticContact CD1-CE3 3.71Å; W62-W115 HydrophobicContact CG-CD2 4.18Å; W62-W115 HydrophobicContact CG-CE3 4.31Å; W62-W115 HydrophobicContact CG-CG 4.49Å; W62-W115 VanDerWaalsContact N-NE1 3.12Å
63L91.3Very high89.4Confident99 Ų9946.4 Ų46.452%0.51828%0.284SS..Hα-helixtrans-59.7-42.2178.5-175.467.4000111.1S60 V65 V66 V67S60-L63 PolarHBondContact O-N 2.85Å; L63-V65 PolarHBondContact O-N 2.96Å; L63-V66 PolarHBondContact O-N 2.71Å; L63-V67 HydrophobicContact CD1-CG2 3.93Å; L63-V67 HydrophobicContact CG-CG2 4.12Å; L63-V67 VanDerWaalsContact O-CB 3.25Å; L63-V67 WeakPolarHBondContact O-CB 3.42Å; L63-V67 WeakPolarHBondContact O-CG2 3.47Å; L63-V67 PolarHBondContact O-N 3Å
64I91.7Very high89.5Confident122 Ų12254.9 Ų54.963%0.62631%0.306SS*.Hα-helixtrans-61.1-45.4177.5-63.2170.6000111S60 S61 W62 G68S60-I64 PolarHBondContact O-N 3.34Å; S61-I64 PolarHBondContact O-N 3.04Å; W62-I64 VanDerWaalsContact C-N 3.29Å; W62-I64 PolarHBondContact O-N 3.38Å; I64-G68 PolarHBondContact O-N 3.2Å
65V92.1Very high89.4Confident30 Ų3056.9 Ų56.918%0.18233%0.325CS..Hα-helixtrans-65.5-47.1179174.10000111S61 W62 L63 G68 V69 G111 L114 W115 L118S61-V65 WeakPolarHBondContact O-CG2 3.39Å; S61-V65 PolarHBondContact O-N 3.03Å; W62-V65 PolarHBondContact O-N 3.49Å; L63-V65 PolarHBondContact O-N 2.96Å; V65-G68 PolarHBondContact O-N 3.33Å; V65-V69 WeakPolarHBondContact O-CG2 3.44Å; V65-V69 PolarHBondContact O-N 3.37Å; V65-G111 WeakPolarHBondContact CG1-O 3.5Å; V65-L114 HydrophobicContact CG1-CB 4.39Å; V65-L114 HydrophobicContact CG1-CD2 4.04Å; V65-L114 HydrophobicContact CG1-CG 4.24Å; V65-W115 HydrophobicContact CB-CB 4.27Å; V65-W115 HydrophobicContact CG1-CB 4.17Å; V65-W115 HydrophobicContact CG2-CB 4.41Å; V65-L118 HydrophobicContact CG2-CD1 4.25Å
66V92.4Very high89.1Confident11 Ų1166 Ų667%0.06737%0.365CS..Hα-helixtrans-64.7-47.3-179.81720000111.1W62 L63 G68 V69 M70 I108W62-V66 HydrophobicContact CD2-CG2 4.13Å; W62-V66 HydrophobicContact CG-CG2 4.38Å; W62-V66 HydrophobicContact CZ2-CG2 3.94Å; W62-V66 WeakPolarHBondContact O-CG2 3.4Å; W62-V66 PolarHBondContact O-N 3.47Å; L63-V66 PolarHBondContact O-N 2.71Å; V66-G68 VanDerWaalsContact C-N 3.3Å; V66-G68 PolarHBondContact O-N 3.05Å; V66-V69 PolarHBondContact O-N 3.25Å; V66-M70 HydrophobicContact CG1-CG 4.21Å; V66-M70 WeakPolarHBondContact O-CB 3.21Å; V66-M70 VanDerWaalsContact O-CG 3.24Å; V66-M70 WeakPolarHBondContact O-CG 3.43Å; V66-M70 PolarHBondContact O-N 2.86Å; V66-I108 HydrophobicContact CG1-CG1 4.03Å
67V92.5Very high88.9Confident74 Ų7470.7 Ų70.745%0.44839%0.388SS..Hα-helixtrans-60.6-42.9176.2171.60000110.3L63 V69 M70 S71L63-V67 HydrophobicContact CD1-CG2 3.93Å; L63-V67 HydrophobicContact CG-CG2 4.12Å; L63-V67 VanDerWaalsContact O-CB 3.25Å; L63-V67 WeakPolarHBondContact O-CB 3.42Å; L63-V67 WeakPolarHBondContact O-CG2 3.47Å; L63-V67 PolarHBondContact O-N 3Å; V67-V69 PolarHBondContact O-N 3.47Å; V67-M70 PolarHBondContact O-N 3.42Å; V67-S71 WeakPolarHBondContact O-CB 3.22Å; V67-S71 PolarHBondContact O-N 2.88Å; V67-S71 PolarHBondContact O-OG 3.25Å
68G91.8Very high88.5Confident35 Ų3573.2 Ų73.236%0.36140%0.399SS..Hα-helixtrans-56.9-49.3174.900000112.6I64 V65 V66 S71 T72I64-G68 PolarHBondContact O-N 3.2Å; V65-G68 PolarHBondContact O-N 3.33Å; V66-G68 VanDerWaalsContact C-N 3.3Å; V66-G68 PolarHBondContact O-N 3.05Å; G68-S71 PolarHBondContact O-N 2.9Å; G68-T72 WeakPolarHBondContact O-CG2 3.38Å; G68-T72 PolarHBondContact O-N 3.48Å; G68-T72 PolarHBondContact O-OG1 3.4Å
69V91.3Very high88Confident8 Ų874.2 Ų74.25%0.04840%0.404CS..Hα-helixtrans-59.6-48.3175.4170.10000110.8V65 V66 V67 S71 T72 M73 I84 F110 L114V65-V69 WeakPolarHBondContact O-CG2 3.44Å; V65-V69 PolarHBondContact O-N 3.37Å; V66-V69 PolarHBondContact O-N 3.25Å; V67-V69 PolarHBondContact O-N 3.47Å; V69-S71 PolarHBondContact O-N 3.25Å; V69-T72 WeakPolarHBondContact CA-OG1 3.45Å; V69-T72 PolarHBondContact O-N 3Å; V69-T72 PolarHBondContact O-OG1 3.32Å; V69-M73 HydrophobicContact CG1-SD 4.17Å; V69-M73 WeakPolarHBondContact O-CG 3.42Å; V69-M73 PolarHBondContact O-N 3.35Å; V69-I84 HydrophobicContact CG1-CD1 3.99Å; V69-F110 HydrophobicContact CG1-CD1 3.98Å; V69-F110 HydrophobicContact CG2-CD1 4.12Å; V69-F110 HydrophobicContact CG2-CE1 4.26Å; V69-L114 HydrophobicContact CG2-CD2 4.4Å
70M89Confident87.8Confident52 Ų5271.5 Ų71.526%0.25639%0.387SS..Hα-helixtrans-62.8-39.9-180-69.8-54.9-60.100112.5V66 V67 M73 Y74 I104V66-M70 HydrophobicContact CG1-CG 4.21Å; V66-M70 WeakPolarHBondContact O-CB 3.21Å; V66-M70 VanDerWaalsContact O-CG 3.24Å; V66-M70 WeakPolarHBondContact O-CG 3.43Å; V66-M70 PolarHBondContact O-N 2.86Å; V67-M70 PolarHBondContact O-N 3.42Å; M70-M73 PolarHBondContact O-N 3.29Å; M70-M73 HydrophobicContact SD-SD 4.15Å; M70-Y74 PolarHBondContact O-N 3.16Å; M70-I104 HydrophobicContact CE-CB 4.25Å; M70-I104 HydrophobicContact CE-CG1 3.92Å; M70-I104 HydrophobicContact CE-CG2 4.28Å
71S90.6Very high87.7Confident70 Ų7075.8 Ų75.849%0.4940%0.403SS..Hα-helixtrans-64.1-41.8175.5-65.80000111.7V67 G68 V69 Y74 A75V67-S71 WeakPolarHBondContact O-CB 3.22Å; V67-S71 PolarHBondContact O-N 2.88Å; V67-S71 PolarHBondContact O-OG 3.25Å; G68-S71 PolarHBondContact O-N 2.9Å; V69-S71 PolarHBondContact O-N 3.25Å; S71-Y74 PolarHBondContact O-N 2.76Å; S71-A75 WeakPolarHBondContact O-CB 3.48Å; S71-A75 PolarHBondContact O-N 2.92Å
72T88.9Confident87.4Confident41 Ų4176 Ų7625%0.25241%0.41SS..Hα-helixtrans-64.8-40.6175.354.50000112.1G68 V69 Y74 A75 K76 I77 P79G68-T72 WeakPolarHBondContact O-CG2 3.38Å; G68-T72 PolarHBondContact O-N 3.48Å; G68-T72 PolarHBondContact O-OG1 3.4Å; V69-T72 WeakPolarHBondContact CA-OG1 3.45Å; V69-T72 PolarHBondContact O-N 3Å; V69-T72 PolarHBondContact O-OG1 3.32Å; T72-Y74 VanDerWaalsContact C-N 3.34Å; T72-Y74 PolarHBondContact O-N 3.28Å; T72-A75 CarbonylContact O-C 3.44Å; T72-A75 PolarHBondContact O-N 3.44Å; T72-K76 PolarHBondContact O-N 3.44Å; T72-K76 VanDerWaalsContact O-N 3.17Å; T72-I77 CarbonylContact C-O 3.6Å; T72-I77 PolarHBondContact O-N 3.15Å; T72-P79 WeakPolarHBondContact OG1-CD 3.01Å; T72-P79 VanDerWaalsContact OG1-CG 3.29Å; T72-P79 WeakPolarHBondContact OG1-CG 3.29Å
73M84.6Confident87.1Confident43 Ų4376 Ų7621%0.21242%0.415CS..Hα-helixtrans-61.6-41.9174.3-70.7-18066.400111.9V69 M70 A75 K76 I84 N103 G107V69-M73 HydrophobicContact CG1-SD 4.17Å; V69-M73 WeakPolarHBondContact O-CG 3.42Å; V69-M73 PolarHBondContact O-N 3.35Å; M70-M73 PolarHBondContact O-N 3.29Å; M70-M73 HydrophobicContact SD-SD 4.15Å; M73-A75 VanDerWaalsContact C-N 3.31Å; M73-A75 PolarHBondContact O-N 3.34Å; M73-K76 PolarHBondContact O-N 3.16Å; M73-I84 HydrophobicContact CE-CG2 3.69Å; M73-I84 HydrophobicContact CG-CD1 4.16Å; M73-I84 HydrophobicContact SD-CD1 3.92Å; M73-I84 HydrophobicContact SD-CG2 4.05Å; M73-N103 HydrophobicContact CE-CB 4.37Å; M73-N103 WeakPolarHBondContact CE-O 3.25Å; M73-G107 VanDerWaalsContact SD-CA 3.51Å
74Y85.3Confident86.8Confident213 Ų21371.7 Ų71.784%0.83539%0.393SS*.Hα-helixtrans-64.7-36.9176-168.4-95.5000112M70 S71 T72 K76M70-Y74 PolarHBondContact O-N 3.16Å; S71-Y74 PolarHBondContact O-N 2.76Å; T72-Y74 VanDerWaalsContact C-N 3.34Å; T72-Y74 PolarHBondContact O-N 3.28Å; Y74-K76 PolarHBondContact O-N 3.35Å
75A87.6Confident86.4Confident61 Ų6168.1 Ų68.150%0.50438%0.382SS..THydrogen-bonded Turntrans-74.33.7172.700000114S71 T72 M73 I77S71-A75 WeakPolarHBondContact O-CB 3.48Å; S71-A75 PolarHBondContact O-N 2.92Å; T72-A75 CarbonylContact O-C 3.44Å; T72-A75 PolarHBondContact O-N 3.44Å; M73-A75 VanDerWaalsContact C-N 3.31Å; M73-A75 PolarHBondContact O-N 3.34Å; A75-I77 HydrophobicContact CB-CD1 4.36Å; A75-I77 HydrophobicContact CB-CG1 4.46Å; A75-I77 PolarHBondContact O-N 2.72Å
76K83.4Confident86.1Confident200 Ų20073.9 Ų73.987%0.8740%0.404SS*.THydrogen-bonded Turntrans58.728.3-176.5-55.3-178179.5179.10114.1T72 M73 Y74T72-K76 PolarHBondContact O-N 3.44Å; T72-K76 VanDerWaalsContact O-N 3.17Å; M73-K76 PolarHBondContact O-N 3.16Å; Y74-K76 PolarHBondContact O-N 3.35Å
77I83.4Confident85.8Confident107 Ų10775.4 Ų75.455%0.54941%0.411SS..  trans-104.6124172.5-60.2171.4000107T72 A75 P79T72-I77 CarbonylContact C-O 3.6Å; T72-I77 PolarHBondContact O-N 3.15Å; A75-I77 HydrophobicContact CB-CD1 4.36Å; A75-I77 HydrophobicContact CB-CG1 4.46Å; A75-I77 PolarHBondContact O-N 2.72Å; I77-P79 WeakPolarHBondContact O-CD 3.42Å
78D78.7Confident85.4Confident73 Ų7373 Ų7339%0.3940%0.396SS..  trans-93.8101.5177-176.59.2000111.1S80 G82D78-S80 PolarHBondContact O-N 3.02Å; D78-S80 WeakPolarHBondContact OD1-CA 3.32Å; D78-S80 VanDerWaalsContact OD1-CB 3.25Å; D78-S80 WeakPolarHBondContact OD1-CB 3.38Å; D78-S80 PolarHBondContact OD1-N 2.64Å; D78-S80 PolarHBondContact OD1-OG 3.33Å; D78-S80 PolarHBondContact OD2-OG 3.05Å; D78-G82 VanDerWaalsContact OD2-CA 3.28Å; D78-G82 WeakPolarHBondContact OD2-CA 3.38Å; D78-G82 PolarHBondContact OD2-N 3.49Å
79P77.1Confident85Confident63 Ų6380.7 Ų80.741%0.40941%0.414SS..THydrogen-bonded Turntrans-75.6-8.6177.236.7-40.9000112.6T72 I77T72-P79 WeakPolarHBondContact OG1-CD 3.01Å; T72-P79 VanDerWaalsContact OG1-CG 3.29Å; T72-P79 WeakPolarHBondContact OG1-CG 3.29Å; I77-P79 WeakPolarHBondContact O-CD 3.42Å
80S82.3Confident84.5Confident4 Ų484.6 Ų84.63%0.02844%0.438CS..THydrogen-bonded Turntrans-95.1-0.3-171.579.30000114.1D78 G82 I83 I84 F110D78-S80 PolarHBondContact O-N 3.02Å; D78-S80 WeakPolarHBondContact OD1-CA 3.32Å; D78-S80 VanDerWaalsContact OD1-CB 3.25Å; D78-S80 WeakPolarHBondContact OD1-CB 3.38Å; D78-S80 PolarHBondContact OD1-N 2.64Å; D78-S80 PolarHBondContact OD1-OG 3.33Å; D78-S80 PolarHBondContact OD2-OG 3.05Å; S80-G82 VanDerWaalsContact C-N 3.26Å; S80-G82 PolarHBondContact O-N 3.14Å; S80-I83 WeakPolarHBondContact O-CB 3.3Å; S80-I83 WeakPolarHBondContact O-CD1 3.32Å; S80-I83 VanDerWaalsContact O-CG1 3.27Å; S80-I83 WeakPolarHBondContact O-CG1 3.42Å; S80-I83 PolarHBondContact O-N 3.45Å; S80-I83 PolarHBondContact OG-N 3.4Å; S80-I84 WeakPolarHBondContact OG-CB 3.44Å; S80-I84 WeakPolarHBondContact OG-CD1 3.32Å; S80-I84 VanDerWaalsContact OG-CG1 3.28Å; S80-I84 WeakPolarHBondContact OG-CG1 3.08Å; S80-I84 PolarHBondContact OG-N 2.86Å; S80-F110 VanDerWaalsContact CB-CE2 3.49Å
81L84.5Confident84.1Confident168 Ų16883.8 Ų83.888%0.8844%0.435SS*.THydrogen-bonded Turntrans52.642.4-176.4-55.9173.5000112.3
82G83.3Confident83.1Confident33 Ų3384.9 Ų84.934%0.3444%0.435SS..THydrogen-bonded Turntrans89.7-2.8177.400000115.9D78 S80 A85 K86D78-G82 VanDerWaalsContact OD2-CA 3.28Å; D78-G82 WeakPolarHBondContact OD2-CA 3.38Å; D78-G82 PolarHBondContact OD2-N 3.49Å; S80-G82 VanDerWaalsContact C-N 3.26Å; S80-G82 PolarHBondContact O-N 3.14Å; G82-A85 PolarHBondContact O-N 3.19Å; G82-K86 PolarHBondContact O-N 2.81Å; G82-K86 VanDerWaalsContact O-N 3.14Å
83I86.3Confident81.8Confident88 Ų8888.7 Ų88.745%0.45146%0.458SS..Hα-helixtrans-67.3-41.4179.9-65170000111.4S80 A85 K86 I87 F110S80-I83 WeakPolarHBondContact O-CB 3.3Å; S80-I83 WeakPolarHBondContact O-CD1 3.32Å; S80-I83 VanDerWaalsContact O-CG1 3.27Å; S80-I83 WeakPolarHBondContact O-CG1 3.42Å; S80-I83 PolarHBondContact O-N 3.45Å; S80-I83 PolarHBondContact OG-N 3.4Å; I83-A85 VanDerWaalsContact C-N 3.29Å; I83-A85 PolarHBondContact O-N 3.46Å; I83-K86 WeakPolarHBondContact O-CB 3.38Å; I83-K86 PolarHBondContact O-N 2.81Å; I83-K86 VanDerWaalsContact O-N 3.1Å; I83-I87 HydrophobicContact CG2-CD1 3.98Å; I83-I87 HydrophobicContact CG2-CG1 4.39Å; I83-I87 WeakPolarHBondContact O-CG1 3.43Å; I83-I87 PolarHBondContact O-N 3.43Å; I83-F110 HydrophobicContact CB-CD2 4.21Å; I83-F110 HydrophobicContact CB-CE2 4.12Å; I83-F110 HydrophobicContact CD1-CE2 4.23Å; I83-F110 HydrophobicContact CG2-CD2 3.77Å; I83-F110 HydrophobicContact CG2-CE2 4.04Å
84I85.4Confident80.8Confident9 Ų989.6 Ų89.65%0.04647%0.467CS..Hα-helixtrans-59.5-43.1177.4-70.7164.5000110.5V69 M73 S80 K86 I87 N88 F110V69-I84 HydrophobicContact CG1-CD1 3.99Å; M73-I84 HydrophobicContact CE-CG2 3.69Å; M73-I84 HydrophobicContact CG-CD1 4.16Å; M73-I84 HydrophobicContact SD-CD1 3.92Å; M73-I84 HydrophobicContact SD-CG2 4.05Å; S80-I84 WeakPolarHBondContact OG-CB 3.44Å; S80-I84 WeakPolarHBondContact OG-CD1 3.32Å; S80-I84 VanDerWaalsContact OG-CG1 3.28Å; S80-I84 WeakPolarHBondContact OG-CG1 3.08Å; S80-I84 PolarHBondContact OG-N 2.86Å; I84-K86 VanDerWaalsContact C-N 3.3Å; I84-K86 PolarHBondContact O-N 2.77Å; I84-I87 PolarHBondContact O-N 3.27Å; I84-N88 WeakPolarHBondContact O-CB 3.27Å; I84-N88 PolarHBondContact O-N 3.3Å; I84-F110 HydrophobicContact CD1-CB 4.27Å; I84-F110 HydrophobicContact CD1-CD1 3.74Å; I84-F110 HydrophobicContact CD1-CE1 4.33Å; I84-F110 HydrophobicContact CD1-CG 4.04Å; I84-F110 HydrophobicContact CG1-CB 3.58Å; I84-F110 HydrophobicContact CG1-CD1 3.84Å; I84-F110 HydrophobicContact CG1-CD2 4.18Å; I84-F110 HydrophobicContact CG1-CG 3.58Å
85A84.4Confident79.8Confident48 Ų4882.8 Ų82.840%0.39746%0.461SS..Hα-helixtrans-63.3-36.3176.600000112.1G82 I83 N88 R89G82-A85 PolarHBondContact O-N 3.19Å; I83-A85 VanDerWaalsContact C-N 3.29Å; I83-A85 PolarHBondContact O-N 3.46Å; A85-N88 PolarHBondContact O-N 3.49Å; A85-R89 WeakPolarHBondContact O-CG 3.05Å; A85-R89 PolarHBondContact O-N 3.11Å
86K85.6Confident78.9Confident151 Ų15190.4 Ų90.466%0.65748%0.478SS*.Hα-helixtrans-68.1-41.5175.5-169.5175.2-177.9177.60112.4G82 I83 I84 N88 R89 T90G82-K86 PolarHBondContact O-N 2.81Å; G82-K86 VanDerWaalsContact O-N 3.14Å; I83-K86 WeakPolarHBondContact O-CB 3.38Å; I83-K86 PolarHBondContact O-N 2.81Å; I83-K86 VanDerWaalsContact O-N 3.1Å; I84-K86 VanDerWaalsContact C-N 3.3Å; I84-K86 PolarHBondContact O-N 2.77Å; K86-N88 VanDerWaalsContact C-N 3.33Å; K86-R89 PolarHBondContact O-N 2.77Å; K86-T90 PolarHBondContact O-N 3.17Å; K86-T90 VanDerWaalsContact O-N 3.16Å; K86-T90 PolarHBondContact O-OG1 3.13Å
87I85.6Confident78.6Confident42 Ų4283.6 Ų83.622%0.21545%0.45CS..Hα-helixtrans-60.8-46.8173.5-66.1166.8000109.5I83 I84 R89 T90 L91 L109 F110I83-I87 HydrophobicContact CG2-CD1 3.98Å; I83-I87 HydrophobicContact CG2-CG1 4.39Å; I83-I87 WeakPolarHBondContact O-CG1 3.43Å; I83-I87 PolarHBondContact O-N 3.43Å; I84-I87 PolarHBondContact O-N 3.27Å; I87-R89 PolarHBondContact O-N 2.91Å; I87-T90 WeakPolarHBondContact O-CB 3.23Å; I87-T90 PolarHBondContact O-N 3Å; I87-L91 HydrophobicContact CG2-CD1 4.07Å; I87-L91 HydrophobicContact CG2-CG 4.39Å; I87-L91 WeakPolarHBondContact O-CG 3.44Å; I87-L91 PolarHBondContact O-N 2.9Å; I87-L109 HydrophobicContact CG2-CB 4.48Å; I87-L109 HydrophobicContact CG2-CD1 4Å; I87-F110 HydrophobicContact CD1-CB 4.08Å
88N84.1Confident78.5Confident25 Ų2581.7 Ų81.713%0.13445%0.446CS..Hα-helixtrans-56.2-52178.6-173.2-42.9000111.4I84 A85 K86 T90 L91 D92 N103 S106I84-N88 WeakPolarHBondContact O-CB 3.27Å; I84-N88 PolarHBondContact O-N 3.3Å; A85-N88 PolarHBondContact O-N 3.49Å; K86-N88 VanDerWaalsContact C-N 3.33Å; N88-T90 PolarHBondContact O-N 3.36Å; N88-T90 VanDerWaalsContact O-N 3.14Å; N88-L91 WeakPolarHBondContact O-CB 3.2Å; N88-L91 PolarHBondContact O-N 3.09Å; N88-D92 PolarHBondContact O-N 3.16Å; N88-N103 PolarHBondContact ND2-OD1 2.79Å; N88-S106 WeakPolarHBondContact CA-OG 3.39Å; N88-S106 WeakPolarHBondContact CB-OG 3.24Å; N88-S106 PolarHBondContact N-OG 3.13Å
89R83.3Confident78.5Confident195 Ų19583.8 Ų83.874%0.73646%0.457SS*.Hα-helixtrans-57-31.2176.2-72.3177.7-174.5179.82.1113.7A85 K86 I87A85-R89 WeakPolarHBondContact O-CG 3.05Å; A85-R89 PolarHBondContact O-N 3.11Å; K86-R89 PolarHBondContact O-N 2.77Å; I87-R89 PolarHBondContact O-N 2.91Å
90T81.7Confident78.6Confident91 Ų9188.2 Ų88.256%0.55847%0.473SS*.Hα-helixtrans-75.4-38.8177.7-47.60000110.9K86 I87 N88 D92 T93K86-T90 PolarHBondContact O-N 3.17Å; K86-T90 VanDerWaalsContact O-N 3.16Å; K86-T90 PolarHBondContact O-OG1 3.13Å; I87-T90 WeakPolarHBondContact O-CB 3.23Å; I87-T90 PolarHBondContact O-N 3Å; N88-T90 PolarHBondContact O-N 3.36Å; N88-T90 VanDerWaalsContact O-N 3.14Å; T90-D92 VanDerWaalsContact C-N 3.29Å; T90-D92 PolarHBondContact O-N 2.78Å; T90-T93 PolarHBondContact O-N 2.65Å; T90-T93 PolarHBondContact O-OG1 2.98Å
91L80.2Confident78.7Confident35 Ų3591 Ų9118%0.18349%0.489CS..Hα-helixtrans-68.2-28.6175.2-68.1174.4000112.6I87 N88 T93 T94 M97 V105 L109I87-L91 HydrophobicContact CG2-CD1 4.07Å; I87-L91 HydrophobicContact CG2-CG 4.39Å; I87-L91 WeakPolarHBondContact O-CG 3.44Å; I87-L91 PolarHBondContact O-N 2.9Å; N88-L91 WeakPolarHBondContact O-CB 3.2Å; N88-L91 PolarHBondContact O-N 3.09Å; L91-T93 PolarHBondContact O-N 3.39Å; L91-T94 WeakPolarHBondContact O-CB 3.18Å; L91-T94 PolarHBondContact O-N 3.38Å; L91-T94 VanDerWaalsContact O-N 3.07Å; L91-T94 PolarHBondContact O-OG1 2.91Å; L91-M97 HydrophobicContact CB-CE 3.92Å; L91-M97 HydrophobicContact CD1-CE 4.44Å; L91-M97 HydrophobicContact CD2-CE 4.19Å; L91-M97 HydrophobicContact CG-CE 4.41Å; L91-V105 HydrophobicContact CD1-CB 4.22Å; L91-V105 HydrophobicContact CD1-CG1 3.78Å; L91-L109 HydrophobicContact CD1-CD1 4.2Å
92D69.3Low78.5Confident92 Ų9283.3 Ų83.349%0.49245%0.449SS..Hα-helixtrans-59.8-30.5178.6-15929.9000112.9N88 T90 T94 G95 Q102N88-D92 PolarHBondContact O-N 3.16Å; T90-D92 VanDerWaalsContact C-N 3.29Å; T90-D92 PolarHBondContact O-N 2.78Å; D92-T94 PolarHBondContact O-N 2.9Å; D92-G95 PolarHBondContact O-N 2.73Å; D92-Q102 PolarHBondContact OD1-NE2 3.25Å
93T61.8Low78.5Confident121 Ų12185.2 Ų85.274%0.74245%0.452SS*.THydrogen-bonded Turntrans-63.9-10.4175.663.30000114.6T90 L91T90-T93 PolarHBondContact O-N 2.65Å; T90-T93 PolarHBondContact O-OG1 2.98Å; L91-T93 PolarHBondContact O-N 3.39Å
94T62.6Low78.6Confident63 Ų6385 Ų8539%0.38745%0.451SS..THydrogen-bonded Turntrans-88-17.217965.10000113.6L91 D92 Y96L91-T94 WeakPolarHBondContact O-CB 3.18Å; L91-T94 PolarHBondContact O-N 3.38Å; L91-T94 VanDerWaalsContact O-N 3.07Å; L91-T94 PolarHBondContact O-OG1 2.91Å; D92-T94 PolarHBondContact O-N 2.9Å; T94-Y96 WeakPolarHBondContact O-CD2 3.36Å; T94-Y96 VanDerWaalsContact O-CE2 3.29Å; T94-Y96 WeakPolarHBondContact O-CE2 3.34Å; T94-Y96 PolarHBondContact O-N 3.15Å
95G65.6Low78.7Confident69 Ų6986.7 Ų86.771%0.71146%0.461SS*.  trans65.5-5.3173.300000117.7D92D92-G95 PolarHBondContact O-N 2.73Å
96Y68.8Low78.9Confident221 Ų22184.4 Ų84.487%0.86744%0.442SS*.  trans-98.42.8-172.7-66.3-72.3000115.3T94T94-Y96 WeakPolarHBondContact O-CD2 3.36Å; T94-Y96 VanDerWaalsContact O-CE2 3.29Å; T94-Y96 WeakPolarHBondContact O-CE2 3.34Å; T94-Y96 PolarHBondContact O-N 3.15Å
97M76.1Confident79Confident58 Ų5877.2 Ų77.229%0.28641%0.411SS..SBendtrans-129.7143-171.8-67.1-172.2-7300113.3L91 T101 Q102 V105L91-M97 HydrophobicContact CB-CE 3.92Å; L91-M97 HydrophobicContact CD1-CE 4.44Å; L91-M97 HydrophobicContact CD2-CE 4.19Å; L91-M97 HydrophobicContact CG-CE 4.41Å; M97-T101 HydrophobicContact CB-CG2 4.44Å; M97-T101 HydrophobicContact CG-CG2 4.41Å; M97-T101 HydrophobicContact SD-CG2 4.25Å; M97-Q102 HydrophobicContact CB-CG 3.78Å; M97-Q102 HydrophobicContact CE-CG 4.38Å; M97-Q102 PolarHBondContact O-NE2 3.14Å; M97-V105 HydrophobicContact SD-CG2 4.3Å
98S81.9Confident79.3Confident66 Ų6678.2 Ų78.246%0.46242%0.416SS..  trans-72.5154172.569.50000112.4Q100 T101 Q102S98-Q100 PolarHBondContact O-N 3.29Å; S98-Q100 VanDerWaalsContact O-N 3.13Å; S98-T101 WeakPolarHBondContact O-CA 3.49Å; S98-T101 WeakPolarHBondContact O-CB 3.34Å; S98-T101 PolarHBondContact O-N 3.08Å; S98-T101 PolarHBondContact OG-N 2.86Å; S98-T101 PolarHBondContact OG-OG1 3.06Å; S98-Q102 WeakPolarHBondContact O-CG 3.16Å; S98-Q102 PolarHBondContact O-N 3.29Å
99N77.9Confident79.6Confident117 Ų11781.3 Ų81.363%0.62643%0.432SS*.Hα-helixtrans-53.7-36-179.9-69.12000113.8N103N99-N103 PolarHBondContact O-N 2.88Å; N99-N103 VanDerWaalsContact O-N 3.15Å; N99-N103 PolarHBondContact O-ND2 3.33Å
100Q80.3Confident80.1Confident156 Ų15673.3 Ų73.373%0.72940%0.403SS*.Hα-helixtrans-67.8-44175.4-72.4-178.8-14.400111.4S98 N103 I104S98-Q100 PolarHBondContact O-N 3.29Å; S98-Q100 VanDerWaalsContact O-N 3.13Å; Q100-N103 PolarHBondContact O-N 2.85Å; Q100-I104 WeakPolarHBondContact O-CG1 3.36Å; Q100-I104 PolarHBondContact O-N 3.02Å; Q100-I104 VanDerWaalsContact O-N 3.1Å
101T83.1Confident80.6Confident62 Ų6269 Ų6938%0.3838%0.376SS..Hα-helixtrans-63.5-44.7177.4-52.40000110.8M97 S98 N103 I104 V105M97-T101 HydrophobicContact CB-CG2 4.44Å; M97-T101 HydrophobicContact CG-CG2 4.41Å; M97-T101 HydrophobicContact SD-CG2 4.25Å; S98-T101 WeakPolarHBondContact O-CA 3.49Å; S98-T101 WeakPolarHBondContact O-CB 3.34Å; S98-T101 PolarHBondContact O-N 3.08Å; S98-T101 PolarHBondContact OG-N 2.86Å; S98-T101 PolarHBondContact OG-OG1 3.06Å; T101-N103 VanDerWaalsContact C-N 3.34Å; T101-N103 PolarHBondContact O-N 3.45Å; T101-I104 PolarHBondContact O-N 2.69Å; T101-V105 HydrophobicContact CG2-CG2 4.25Å; T101-V105 VanDerWaalsContact O-CG2 3.29Å; T101-V105 WeakPolarHBondContact O-CG2 3.48Å; T101-V105 PolarHBondContact O-N 3.35Å
102Q81.9Confident81.2Confident7 Ų769.5 Ų69.53%0.03338%0.381CS..Hα-helixtrans-58.5-43177.1-70175-14.900112.3D92 M97 S98 S106D92-Q102 PolarHBondContact OD1-NE2 3.25Å; M97-Q102 HydrophobicContact CB-CG 3.78Å; M97-Q102 HydrophobicContact CE-CG 4.38Å; M97-Q102 PolarHBondContact O-NE2 3.14Å; S98-Q102 WeakPolarHBondContact O-CG 3.16Å; S98-Q102 PolarHBondContact O-N 3.29Å; Q102-S106 VanDerWaalsContact O-CB 3.27Å; Q102-S106 WeakPolarHBondContact O-CB 3.5Å; Q102-S106 PolarHBondContact O-N 3.12Å; Q102-S106 PolarHBondContact O-OG 2.88Å
103N83.3Confident82.3Confident74 Ų7467.1 Ų67.140%0.39638%0.378SS..Hα-helixtrans-63.6-44.3176.3-80.5-40.8000112M73 N88 N99 Q100 T101 S106 G107M73-N103 HydrophobicContact CE-CB 4.37Å; M73-N103 WeakPolarHBondContact CE-O 3.25Å; N88-N103 PolarHBondContact ND2-OD1 2.79Å; N99-N103 PolarHBondContact O-N 2.88Å; N99-N103 VanDerWaalsContact O-N 3.15Å; N99-N103 PolarHBondContact O-ND2 3.33Å; Q100-N103 PolarHBondContact O-N 2.85Å; T101-N103 VanDerWaalsContact C-N 3.34Å; T101-N103 PolarHBondContact O-N 3.45Å; N103-S106 PolarHBondContact O-N 3.24Å; N103-G107 PolarHBondContact O-N 3.45Å
104I87.4Confident83.8Confident83 Ų8364.6 Ų64.643%0.42636%0.36SS..Hα-helixtrans-63-48.5177.3-66.8166.8000110.8M70 Q100 T101 S106 G107 I108M70-I104 HydrophobicContact CE-CB 4.25Å; M70-I104 HydrophobicContact CE-CG1 3.92Å; M70-I104 HydrophobicContact CE-CG2 4.28Å; Q100-I104 WeakPolarHBondContact O-CG1 3.36Å; Q100-I104 PolarHBondContact O-N 3.02Å; Q100-I104 VanDerWaalsContact O-N 3.1Å; T101-I104 PolarHBondContact O-N 2.69Å; I104-S106 VanDerWaalsContact C-N 3.34Å; I104-S106 PolarHBondContact O-N 2.99Å; I104-G107 PolarHBondContact O-N 3.01Å; I104-I108 HydrophobicContact CG2-CD1 3.75Å; I104-I108 HydrophobicContact CG2-CG1 4.44Å; I104-I108 WeakPolarHBondContact O-CG1 3.5Å; I104-I108 PolarHBondContact O-N 3.04Å
105V87.5Confident85.3Confident45 Ų4563 Ų6327%0.27335%0.347SS..Hα-helixtrans-61.5-43.1178.71760000110.9L91 M97 T101 G107 I108 L109L91-V105 HydrophobicContact CD1-CB 4.22Å; L91-V105 HydrophobicContact CD1-CG1 3.78Å; M97-V105 HydrophobicContact SD-CG2 4.3Å; T101-V105 HydrophobicContact CG2-CG2 4.25Å; T101-V105 VanDerWaalsContact O-CG2 3.29Å; T101-V105 WeakPolarHBondContact O-CG2 3.48Å; T101-V105 PolarHBondContact O-N 3.35Å; V105-G107 PolarHBondContact O-N 2.84Å; V105-I108 PolarHBondContact O-N 3.33Å; V105-L109 HydrophobicContact CG1-CD1 3.89Å; V105-L109 HydrophobicContact CG1-CG 4.19Å; V105-L109 WeakPolarHBondContact O-CB 3.44Å; V105-L109 VanDerWaalsContact O-CG 3.29Å; V105-L109 WeakPolarHBondContact O-CG 3.43Å; V105-L109 PolarHBondContact O-N 3.29Å
106S87.9Confident86.6Confident0 Ų063.1 Ų63.10%033%0.333CS..Hα-helixtrans-62-42.3177.7-57.60000112.2N88 Q102 N103 I104 L109 F110N88-S106 WeakPolarHBondContact CA-OG 3.39Å; N88-S106 WeakPolarHBondContact CB-OG 3.24Å; N88-S106 PolarHBondContact N-OG 3.13Å; Q102-S106 VanDerWaalsContact O-CB 3.27Å; Q102-S106 WeakPolarHBondContact O-CB 3.5Å; Q102-S106 PolarHBondContact O-N 3.12Å; Q102-S106 PolarHBondContact O-OG 2.88Å; N103-S106 PolarHBondContact O-N 3.24Å; I104-S106 VanDerWaalsContact C-N 3.34Å; I104-S106 PolarHBondContact O-N 2.99Å; S106-L109 PolarHBondContact O-N 2.89Å; S106-F110 WeakPolarHBondContact O-CB 3.36Å; S106-F110 PolarHBondContact O-N 2.89Å
107G89.1Confident87.7Confident0 Ų055 Ų550%031%0.312CS..Hα-helixtrans-64-42.9175.300000113M73 N103 I104 V105 G111M73-G107 VanDerWaalsContact SD-CA 3.51Å; N103-G107 PolarHBondContact O-N 3.45Å; I104-G107 PolarHBondContact O-N 3.01Å; V105-G107 PolarHBondContact O-N 2.84Å; G107-G111 PolarHBondContact O-N 3.24Å
108I91.4Very high88.4Confident63 Ų6356 Ų5632%0.32332%0.318SS..Hα-helixtrans-65.2-44.4175.9-68169.5000111.2W62 V66 I104 V105 G111 T112W62-I108 HydrophobicContact CZ2-CG2 4.42Å; V66-I108 HydrophobicContact CG1-CG1 4.03Å; I104-I108 HydrophobicContact CG2-CD1 3.75Å; I104-I108 HydrophobicContact CG2-CG1 4.44Å; I104-I108 WeakPolarHBondContact O-CG1 3.5Å; I104-I108 PolarHBondContact O-N 3.04Å; V105-I108 PolarHBondContact O-N 3.33Å; I108-G111 PolarHBondContact O-N 2.93Å; I108-T112 VanDerWaalsContact O-CB 3.26Å; I108-T112 WeakPolarHBondContact O-CB 3.45Å; I108-T112 PolarHBondContact O-N 3.09Å; I108-T112 PolarHBondContact O-OG1 3.21Å
109L90.9Very high88.9Confident89 Ų8953.5 Ų53.547%0.46630%0.299SS..Hα-helixtrans-62.6-47.5178.4-74.5175.4000111.1I87 L91 V105 S106 T112 G113I87-L109 HydrophobicContact CG2-CB 4.48Å; I87-L109 HydrophobicContact CG2-CD1 4Å; L91-L109 HydrophobicContact CD1-CD1 4.2Å; V105-L109 HydrophobicContact CG1-CD1 3.89Å; V105-L109 HydrophobicContact CG1-CG 4.19Å; V105-L109 WeakPolarHBondContact O-CB 3.44Å; V105-L109 VanDerWaalsContact O-CG 3.29Å; V105-L109 WeakPolarHBondContact O-CG 3.43Å; V105-L109 PolarHBondContact O-N 3.29Å; S106-L109 PolarHBondContact O-N 2.89Å; L109-T112 PolarHBondContact O-N 3.41Å; L109-G113 PolarHBondContact O-N 2.93Å
110F93.1Very high89.5Confident28 Ų2852 Ų5212%0.12329%0.294CS..Hα-helixtrans-62.4-49.1175.7178.2-98.9000111.7V69 S80 I83 I84 I87 S106 T112 G113 L114V69-F110 HydrophobicContact CG1-CD1 3.98Å; V69-F110 HydrophobicContact CG2-CD1 4.12Å; V69-F110 HydrophobicContact CG2-CE1 4.26Å; S80-F110 VanDerWaalsContact CB-CE2 3.49Å; I83-F110 HydrophobicContact CB-CD2 4.21Å; I83-F110 HydrophobicContact CB-CE2 4.12Å; I83-F110 HydrophobicContact CD1-CE2 4.23Å; I83-F110 HydrophobicContact CG2-CD2 3.77Å; I83-F110 HydrophobicContact CG2-CE2 4.04Å; I84-F110 HydrophobicContact CD1-CB 4.27Å; I84-F110 HydrophobicContact CD1-CD1 3.74Å; I84-F110 HydrophobicContact CD1-CE1 4.33Å; I84-F110 HydrophobicContact CD1-CG 4.04Å; I84-F110 HydrophobicContact CG1-CB 3.58Å; I84-F110 HydrophobicContact CG1-CD1 3.84Å; I84-F110 HydrophobicContact CG1-CD2 4.18Å; I84-F110 HydrophobicContact CG1-CG 3.58Å; I87-F110 HydrophobicContact CD1-CB 4.08Å; S106-F110 WeakPolarHBondContact O-CB 3.36Å; S106-F110 PolarHBondContact O-N 2.89Å; F110-T112 VanDerWaalsContact C-N 3.28Å; F110-T112 PolarHBondContact O-N 3.39Å; F110-G113 PolarHBondContact O-N 3.4Å; F110-G113 VanDerWaalsContact O-N 3.15Å; F110-L114 HydrophobicContact CE1-CD2 4.16Å; F110-L114 WeakPolarHBondContact O-CB 3.41Å; F110-L114 PolarHBondContact O-N 3.39Å
111G92.8Very high90.1Very high0 Ų048.6 Ų48.60%028%0.284CS..Hα-helixtrans-60.3-37.3178.900000112.8V65 G107 I108 W115V65-G111 WeakPolarHBondContact CG1-O 3.5Å; G107-G111 PolarHBondContact O-N 3.24Å; I108-G111 PolarHBondContact O-N 2.93Å; G111-W115 VanDerWaalsContact O-CB 3.31Å; G111-W115 WeakPolarHBondContact O-CB 3.45Å; G111-W115 PolarHBondContact O-N 3.45Å
112T92.9Very high90.5Very high45 Ų4548.5 Ų48.528%0.27628%0.28SS..Hα-helixtrans-67.6-45.8173.8-56.90000111.4W62 I108 L109 F110 L114 W115 V116W62-T112 PolarHBondContact NE1-OG1 3.16Å; I108-T112 VanDerWaalsContact O-CB 3.26Å; I108-T112 WeakPolarHBondContact O-CB 3.45Å; I108-T112 PolarHBondContact O-N 3.09Å; I108-T112 PolarHBondContact O-OG1 3.21Å; L109-T112 PolarHBondContact O-N 3.41Å; F110-T112 VanDerWaalsContact C-N 3.28Å; F110-T112 PolarHBondContact O-N 3.39Å; T112-L114 PolarHBondContact O-N 3.5Å; T112-W115 PolarHBondContact O-N 3.31Å; T112-V116 WeakPolarHBondContact O-CG2 3.16Å; T112-V116 PolarHBondContact O-N 3.16Å
113G92.8Very high90.9Very high42 Ų4250.8 Ų50.843%0.43329%0.288SS..Hα-helixtrans-60.1-44.4175.900000112.5L109 F110 V116 A117L109-G113 PolarHBondContact O-N 2.93Å; F110-G113 PolarHBondContact O-N 3.4Å; F110-G113 VanDerWaalsContact O-N 3.15Å; G113-V116 PolarHBondContact O-N 3.11Å; G113-A117 WeakPolarHBondContact O-CB 3.45Å; G113-A117 PolarHBondContact O-N 2.73Å
114L93.3Very high91.4Very high68 Ų6854.1 Ų54.136%0.35630%0.296SS..Hα-helixtrans-60.4-46.3174.3179.360.9000111.2V65 V69 F110 T112 V116 A117 L118V65-L114 HydrophobicContact CG1-CB 4.39Å; V65-L114 HydrophobicContact CG1-CD2 4.04Å; V65-L114 HydrophobicContact CG1-CG 4.24Å; V69-L114 HydrophobicContact CG2-CD2 4.4Å; F110-L114 HydrophobicContact CE1-CD2 4.16Å; F110-L114 WeakPolarHBondContact O-CB 3.41Å; F110-L114 PolarHBondContact O-N 3.39Å; T112-L114 PolarHBondContact O-N 3.5Å; L114-V116 PolarHBondContact O-N 3.27Å; L114-A117 PolarHBondContact O-N 3.47Å; L114-L118 HydrophobicContact CD1-CG 4.42Å; L114-L118 HydrophobicContact CG-CD1 4.24Å; L114-L118 WeakPolarHBondContact O-CB 3.32Å; L114-L118 VanDerWaalsContact O-CG 3.28Å; L114-L118 WeakPolarHBondContact O-CG 3.47Å; L114-L118 PolarHBondContact O-N 2.72Å
115W94.1Very high91.7Very high31 Ų3152 Ų5212%0.11729%0.288CS..Hα-helixtrans-61.9-42.3177.1176.978.6000112.6V54 S61 W62 V65 G111 T112 L118 I119V54-W115 HydrophobicContact CB-CH2 4.06Å; V54-W115 HydrophobicContact CB-CZ2 4.19Å; V54-W115 HydrophobicContact CG1-CH2 3.62Å; V54-W115 HydrophobicContact CG1-CZ2 4.25Å; V54-W115 HydrophobicContact CG1-CZ3 4.46Å; S61-W115 PolarHBondContact OG-NE1 3.46Å; W62-W115 VanDerWaalsContact CA-CD1 3.47Å; W62-W115 HydrophobicContact CB-CD2 3.72Å; W62-W115 HydrophobicContact CB-CE3 4.22Å; W62-W115 HydrophobicContact CB-CG 4.05Å; W62-W115 HydrophobicContact CB-CH2 4.25Å; W62-W115 HydrophobicContact CB-CZ2 3.78Å; W62-W115 HydrophobicContact CB-CZ3 4.47Å; W62-W115 AromaticContact CD1-CD2 3.81Å; W62-W115 AromaticContact CD1-CE3 3.71Å; W62-W115 HydrophobicContact CG-CD2 4.18Å; W62-W115 HydrophobicContact CG-CE3 4.31Å; W62-W115 HydrophobicContact CG-CG 4.49Å; W62-W115 VanDerWaalsContact N-NE1 3.12Å; V65-W115 HydrophobicContact CB-CB 4.27Å; V65-W115 HydrophobicContact CG1-CB 4.17Å; V65-W115 HydrophobicContact CG2-CB 4.41Å; G111-W115 VanDerWaalsContact O-CB 3.31Å; G111-W115 WeakPolarHBondContact O-CB 3.45Å; G111-W115 PolarHBondContact O-N 3.45Å; T112-W115 PolarHBondContact O-N 3.31Å; W115-L118 PolarHBondContact O-N 3.42Å; W115-I119 HydrophobicContact CD2-CD1 3.56Å; W115-I119 HydrophobicContact CD2-CG1 4.48Å; W115-I119 HydrophobicContact CE3-CD1 3.8Å; W115-I119 HydrophobicContact CG-CD1 4.34Å; W115-I119 HydrophobicContact CH2-CD1 3.57Å; W115-I119 HydrophobicContact CZ2-CD1 3.27Å; W115-I119 HydrophobicContact CZ3-CD1 3.8Å; W115-I119 WeakPolarHBondContact O-CG1 3.36Å; W115-I119 PolarHBondContact O-N 3.05Å
116V92.2Very high92.1Very high71 Ų7149.8 Ų49.843%0.4328%0.275SS..Hα-helixtrans-61.9-45.8174171.10000110.8T112 G113 L114 L118 I119 V120T112-V116 WeakPolarHBondContact O-CG2 3.16Å; T112-V116 PolarHBondContact O-N 3.16Å; G113-V116 PolarHBondContact O-N 3.11Å; L114-V116 PolarHBondContact O-N 3.27Å; V116-L118 VanDerWaalsContact C-N 3.32Å; V116-L118 PolarHBondContact O-N 3.21Å; V116-I119 PolarHBondContact O-N 3.36Å; V116-V120 HydrophobicContact CG1-CG2 4.37Å; V116-V120 WeakPolarHBondContact O-CG2 3.38Å; V116-V120 PolarHBondContact O-N 3.35Å
117A92Very high92.4Very high50 Ų5052.3 Ų52.341%0.41329%0.286SS..Hα-helixtrans-60.3-41.7177.200000111.9G113 L114 V120 T121G113-A117 WeakPolarHBondContact O-CB 3.45Å; G113-A117 PolarHBondContact O-N 2.73Å; L114-A117 PolarHBondContact O-N 3.47Å; A117-V120 PolarHBondContact O-N 2.96Å; A117-T121 WeakPolarHBondContact O-CB 3.44Å; A117-T121 PolarHBondContact O-N 3.27Å; A117-T121 PolarHBondContact O-OG1 3.08Å
118L91.3Very high92.7Very high80 Ų8056.4 Ų56.442%0.41931%0.306SS..Hα-helixtrans-62-44.2174.4-72171.7000111.7V65 L114 W115 V116 T121 M122V65-L118 HydrophobicContact CG2-CD1 4.25Å; L114-L118 HydrophobicContact CD1-CG 4.42Å; L114-L118 HydrophobicContact CG-CD1 4.24Å; L114-L118 WeakPolarHBondContact O-CB 3.32Å; L114-L118 VanDerWaalsContact O-CG 3.28Å; L114-L118 WeakPolarHBondContact O-CG 3.47Å; L114-L118 PolarHBondContact O-N 2.72Å; W115-L118 PolarHBondContact O-N 3.42Å; V116-L118 VanDerWaalsContact C-N 3.32Å; V116-L118 PolarHBondContact O-N 3.21Å; L118-T121 PolarHBondContact O-N 3.38Å; L118-M122 WeakPolarHBondContact O-CB 3.38Å; L118-M122 VanDerWaalsContact O-CG 3.31Å; L118-M122 WeakPolarHBondContact O-CG 3.37Å; L118-M122 PolarHBondContact O-N 2.99Å
119I91.3Very high92.9Very high12 Ų1254.8 Ų54.86%0.06230%0.298CS..Hα-helixtrans-61.2-49.2176.6-73169.1000111.4V54 A57 W115 V116 T121 M122 R123V54-I119 HydrophobicContact CB-CD1 3.96Å; V54-I119 HydrophobicContact CG1-CD1 4.42Å; A57-I119 HydrophobicContact CB-CD1 3.94Å; A57-I119 HydrophobicContact CB-CG1 3.51Å; W115-I119 HydrophobicContact CD2-CD1 3.56Å; W115-I119 HydrophobicContact CD2-CG1 4.48Å; W115-I119 HydrophobicContact CE3-CD1 3.8Å; W115-I119 HydrophobicContact CG-CD1 4.34Å; W115-I119 HydrophobicContact CH2-CD1 3.57Å; W115-I119 HydrophobicContact CZ2-CD1 3.27Å; W115-I119 HydrophobicContact CZ3-CD1 3.8Å; W115-I119 WeakPolarHBondContact O-CG1 3.36Å; W115-I119 PolarHBondContact O-N 3.05Å; V116-I119 PolarHBondContact O-N 3.36Å; I119-T121 PolarHBondContact O-N 3.43Å; I119-M122 PolarHBondContact O-N 2.97Å; I119-R123 VanDerWaalsContact O-CB 3.28Å; I119-R123 WeakPolarHBondContact O-CB 3.41Å; I119-R123 PolarHBondContact O-N 3.5Å
120V90.4Very high93.2Very high85 Ų8550.9 Ų50.952%0.51528%0.278SS..Hα-helixtrans-59.6-42.6179.8171.50000109.8V116 A117 R123 Y124V116-V120 HydrophobicContact CG1-CG2 4.37Å; V116-V120 WeakPolarHBondContact O-CG2 3.38Å; V116-V120 PolarHBondContact O-N 3.35Å; A117-V120 PolarHBondContact O-N 2.96Å; V120-R123 PolarHBondContact O-N 2.91Å; V120-Y124 WeakPolarHBondContact O-CB 3.32Å; V120-Y124 PolarHBondContact O-N 2.99Å
121T92.3Very high93.3Very high85 Ų8552 Ų5252%0.52129%0.289SS..Hα-helixtrans-62.5-51.8176-55.80000111.4A117 L118 I119 R123 Y124 S125A117-T121 WeakPolarHBondContact O-CB 3.44Å; A117-T121 PolarHBondContact O-N 3.27Å; A117-T121 PolarHBondContact O-OG1 3.08Å; L118-T121 PolarHBondContact O-N 3.38Å; I119-T121 PolarHBondContact O-N 3.43Å; T121-R123 VanDerWaalsContact C-N 3.31Å; T121-R123 PolarHBondContact O-N 3.1Å; T121-Y124 PolarHBondContact O-N 3.16Å; T121-S125 WeakPolarHBondContact O-CB 3.13Å; T121-S125 PolarHBondContact O-N 2.85Å; T121-S125 PolarHBondContact O-OG 3.07Å; T121-S125 VanDerWaalsContact O-OG 3.05Å
122M91.6Very high93.3Very high60 Ų6056.2 Ų56.230%0.29631%0.305SS..Hα-helixtrans-59-41.9178.2-72.3-179.676.600112.3P56 L118 I119 S125 L126P56-M122 HydrophobicContact CB-CE 4.37Å; P56-M122 HydrophobicContact CG-CB 3.73Å; P56-M122 HydrophobicContact CG-CE 3.92Å; L118-M122 WeakPolarHBondContact O-CB 3.38Å; L118-M122 VanDerWaalsContact O-CG 3.31Å; L118-M122 WeakPolarHBondContact O-CG 3.37Å; L118-M122 PolarHBondContact O-N 2.99Å; I119-M122 PolarHBondContact O-N 2.97Å; M122-S125 PolarHBondContact O-N 2.83Å; M122-L126 WeakPolarHBondContact O-CB 3.42Å; M122-L126 PolarHBondContact O-N 3.1Å
123R91.6Very high93.3Very high56 Ų5655.3 Ų55.321%0.21130%0.298CS..Hα-helixtrans-63.6-45.7176.9177.4176.9-63.5168.24.3111.4G53 Y55 I119 V120 T121 L126 K127 T169G53-R123 PolarHBondContact O-NH2 3.34Å; Y55-R123 PolarHBondContact O-NH2 3.33Å; I119-R123 VanDerWaalsContact O-CB 3.28Å; I119-R123 WeakPolarHBondContact O-CB 3.41Å; I119-R123 PolarHBondContact O-N 3.5Å; V120-R123 PolarHBondContact O-N 2.91Å; T121-R123 VanDerWaalsContact C-N 3.31Å; T121-R123 PolarHBondContact O-N 3.1Å; R123-L126 PolarHBondContact O-N 3.27Å; R123-K127 WeakPolarHBondContact O-CB 3.29Å; R123-K127 PolarHBondContact O-N 3.28Å; R123-T169 PolarHBondContact NE-OG1 2.79Å
124Y92.6Very high93.2Very high144 Ų14454.4 Ų54.457%0.56529%0.289SS*.Hα-helixtrans-64.5-43.7177.9-172-96.5000111.1V120 T121 L126 K127 M128V120-Y124 WeakPolarHBondContact O-CB 3.32Å; V120-Y124 PolarHBondContact O-N 2.99Å; T121-Y124 PolarHBondContact O-N 3.16Å; Y124-L126 PolarHBondContact O-N 2.91Å; Y124-K127 WeakPolarHBondContact O-CB 3.32Å; Y124-K127 PolarHBondContact O-N 3.46Å; Y124-M128 HydrophobicContact CD1-CG 3.91Å; Y124-M128 HydrophobicContact CD2-CE 4.47Å; Y124-M128 HydrophobicContact CE1-CE 4.24Å; Y124-M128 HydrophobicContact CE1-CG 3.54Å; Y124-M128 HydrophobicContact CE1-SD 3.99Å; Y124-M128 HydrophobicContact CE2-CE 3.81Å; Y124-M128 WeakPolarHBondContact O-CG 3.35Å; Y124-M128 PolarHBondContact O-N 3.34Å
125S94.8Very high93.1Very high37 Ų3752.1 Ų52.126%0.25928%0.275SS..Hα-helixtrans-58-48173.6-62.90000111.7T121 M122 K127 M128 L129T121-S125 WeakPolarHBondContact O-CB 3.13Å; T121-S125 PolarHBondContact O-N 2.85Å; T121-S125 PolarHBondContact O-OG 3.07Å; T121-S125 VanDerWaalsContact O-OG 3.05Å; M122-S125 PolarHBondContact O-N 2.83Å; S125-K127 VanDerWaalsContact C-N 3.31Å; S125-K127 PolarHBondContact O-N 3.04Å; S125-M128 PolarHBondContact O-N 3.01Å; S125-L129 VanDerWaalsContact O-CG 3.29Å; S125-L129 WeakPolarHBondContact O-CG 3.32Å; S125-L129 PolarHBondContact O-N 2.94Å
126L94.9Very high92.9Very high0 Ų052.1 Ų52.10%028%0.277CS..Hα-helixtrans-61.7-40.5176.3-175.858.2000111.5Y55 M122 R123 Y124 L129 L130 V154 F157 F167Y55-L126 HydrophobicContact CE1-CD2 4.46Å; M122-L126 WeakPolarHBondContact O-CB 3.42Å; M122-L126 PolarHBondContact O-N 3.1Å; R123-L126 PolarHBondContact O-N 3.27Å; Y124-L126 PolarHBondContact O-N 2.91Å; L126-L129 PolarHBondContact O-N 3.38Å; L126-L130 HydrophobicContact CD1-CD1 4.17Å; L126-L130 HydrophobicContact CD1-CG 4.13Å; L126-L130 HydrophobicContact CG-CD1 3.99Å; L126-L130 HydrophobicContact CG-CG 4.36Å; L126-L130 WeakPolarHBondContact O-CB 3.48Å; L126-L130 VanDerWaalsContact O-CG 3.25Å; L126-L130 WeakPolarHBondContact O-CG 3.41Å; L126-L130 PolarHBondContact O-N 3.43Å; L126-V154 HydrophobicContact CD1-CG1 4.3Å; L126-F157 HydrophobicContact CB-CB 4.38Å; L126-F157 HydrophobicContact CD1-CB 4.27Å; L126-F167 HydrophobicContact CD2-CD1 4.18Å; L126-F167 HydrophobicContact CD2-CE1 4.21Å
127K95.4Very high92.8Very high53 Ų5352.6 Ų52.623%0.2327%0.274CS..Hα-helixtrans-62.9-42.7175.3-175.1178.2-178.6-177.30112.6R123 Y124 S125 L130 S131 S170R123-K127 WeakPolarHBondContact O-CB 3.29Å; R123-K127 PolarHBondContact O-N 3.28Å; Y124-K127 WeakPolarHBondContact O-CB 3.32Å; Y124-K127 PolarHBondContact O-N 3.46Å; S125-K127 VanDerWaalsContact C-N 3.31Å; S125-K127 PolarHBondContact O-N 3.04Å; K127-L130 PolarHBondContact O-N 3.23Å; K127-S131 WeakPolarHBondContact O-CB 3.16Å; K127-S131 PolarHBondContact O-N 2.95Å; K127-S131 PolarHBondContact O-OG 2.89Å; K127-S170 WeakPolarHBondContact CA-O 3.45Å; K127-S170 VanDerWaalsContact CB-O 3.3Å; K127-S170 WeakPolarHBondContact CB-O 3.25Å
128M95.1Very high92.5Very high85 Ų8552.1 Ų52.142%0.41926%0.264SS..Hα-helixtrans-63.3-44.2175.3-69.5-59.8103.800111.1Y124 S125 L130 S131Y124-M128 HydrophobicContact CD1-CG 3.91Å; Y124-M128 HydrophobicContact CD2-CE 4.47Å; Y124-M128 HydrophobicContact CE1-CE 4.24Å; Y124-M128 HydrophobicContact CE1-CG 3.54Å; Y124-M128 HydrophobicContact CE1-SD 3.99Å; Y124-M128 HydrophobicContact CE2-CE 3.81Å; Y124-M128 WeakPolarHBondContact O-CG 3.35Å; Y124-M128 PolarHBondContact O-N 3.34Å; S125-M128 PolarHBondContact O-N 3.01Å; M128-L130 PolarHBondContact O-N 3.49Å; M128-S131 WeakPolarHBondContact O-CB 3.25Å; M128-S131 PolarHBondContact O-N 2.71Å
129L96.1Very high91.8Very high29 Ų2954.6 Ų54.615%0.15227%0.273CS..Hα-helixtrans-59.7-46.8174.7-70.2168.5000111.3S125 L126 S131 Y132 W150 L153 V154 F157S125-L129 VanDerWaalsContact O-CG 3.29Å; S125-L129 WeakPolarHBondContact O-CG 3.32Å; S125-L129 PolarHBondContact O-N 2.94Å; L126-L129 PolarHBondContact O-N 3.38Å; L129-S131 PolarHBondContact O-N 3.47Å; L129-Y132 WeakPolarHBondContact O-CB 3.39Å; L129-Y132 PolarHBondContact O-N 2.81Å; L129-Y132 VanDerWaalsContact O-N 3.15Å; L129-W150 PolarHBondContact O-NE1 2.68Å; L129-L153 HydrophobicContact CD1-CB 4.04Å; L129-L153 HydrophobicContact CD2-CB 3.96Å; L129-L153 HydrophobicContact CD2-CD1 4.16Å; L129-V154 HydrophobicContact CB-CG2 3.9Å; L129-V154 HydrophobicContact CD1-CG2 4.5Å; L129-F157 HydrophobicContact CD1-CB 4.19Å; L129-F157 HydrophobicContact CD1-CD2 3.77Å; L129-F157 HydrophobicContact CD1-CG 4.16Å
130L96.1Very high90.8Very high8 Ų863.5 Ų63.54%0.04231%0.314CS..Hα-helixtrans-70.9-15.9178.8-67.1177000113.6L126 K127 M128 Y132 V154 L171 P302L126-L130 HydrophobicContact CD1-CD1 4.17Å; L126-L130 HydrophobicContact CD1-CG 4.13Å; L126-L130 HydrophobicContact CG-CD1 3.99Å; L126-L130 HydrophobicContact CG-CG 4.36Å; L126-L130 WeakPolarHBondContact O-CB 3.48Å; L126-L130 VanDerWaalsContact O-CG 3.25Å; L126-L130 WeakPolarHBondContact O-CG 3.41Å; L126-L130 PolarHBondContact O-N 3.43Å; K127-L130 PolarHBondContact O-N 3.23Å; M128-L130 PolarHBondContact O-N 3.49Å; L130-Y132 PolarHBondContact O-N 3.19Å; L130-V154 HydrophobicContact CD2-CG1 4.18Å; L130-L171 HydrophobicContact CD1-CD2 4.47Å; L130-P302 HydrophobicContact CD1-CG 3.87Å; L130-P302 HydrophobicContact CD2-CG 4.23Å
131S95.3Very high89.8Confident50 Ų5063 Ų6335%0.3533%0.327SS..Hα-helixtrans-74.8-16.5172.8-57.20000112.3K127 M128 L129 H133K127-S131 WeakPolarHBondContact O-CB 3.16Å; K127-S131 PolarHBondContact O-N 2.95Å; K127-S131 PolarHBondContact O-OG 2.89Å; M128-S131 WeakPolarHBondContact O-CB 3.25Å; M128-S131 PolarHBondContact O-N 2.71Å; L129-S131 PolarHBondContact O-N 3.47Å; S131-H133 PolarHBondContact O-CE1 3.34Å; S131-H133 PolarHBondContact O-N 2.89Å; S131-H133 PolarHBondContact O-ND1 3.45Å
132Y93.8Very high89.2Confident89 Ų8965.7 Ų65.735%0.34933%0.332SS..  trans-78.8119.3174176.1-105.7000111L129 L130 G134 W135 W150L129-Y132 WeakPolarHBondContact O-CB 3.39Å; L129-Y132 PolarHBondContact O-N 2.81Å; L129-Y132 VanDerWaalsContact O-N 3.15Å; L130-Y132 PolarHBondContact O-N 3.19Å; Y132-G134 VanDerWaalsContact CZ-CA 3.49Å; Y132-W135 HydrophobicContact CE1-CB 4.4Å; Y132-W135 VanDerWaalsContact O-CD1 3.24Å; Y132-W135 PolarHBondContact O-NE1 3.41Å; Y132-W135 VanDerWaalsContact O-NE1 3.14Å; Y132-W150 AromaticContact CD1-CD1 3.82Å; Y132-W150 AromaticContact CD1-CD2 3.89Å; Y132-W150 HydrophobicContact CD1-CD2 3.89Å; Y132-W150 AromaticContact CD1-CE2 3.81Å; Y132-W150 AromaticContact CD1-CG 3.91Å; Y132-W150 HydrophobicContact CD1-CG 3.91Å; Y132-W150 HydrophobicContact CD1-CZ2 4.38Å; Y132-W150 AromaticContact CD1-NE1 3.74Å; Y132-W150 HydrophobicContact CE1-CD2 4.37Å; Y132-W150 HydrophobicContact CE1-CG 4.34Å
133H93.3Very high88.9Confident27 Ų2765.8 Ų65.813%0.12533%0.333CS..  trans-115.27-180-62.999.6000113.7S131 W135 M136 F597 T649S131-H133 PolarHBondContact O-CE1 3.34Å; S131-H133 PolarHBondContact O-N 2.89Å; S131-H133 PolarHBondContact O-ND1 3.45Å; H133-W135 PolarHBondContact O-N 3.39Å; H133-W135 VanDerWaalsContact O-N 3.15Å; H133-M136 WeakPolarHBondContact O-CB 3.31Å; H133-M136 PolarHBondContact O-N 3.37Å; H133-F597 AromaticContact CE1-CE1 3.48Å; H133-F597 VanDerWaalsContact CE1-CE1 3.48Å; H133-F597 WeakPolarHBondContact CE1-CE1 3.01Å; H133-F597 AromaticContact CE1-CZ 3.56Å; H133-F597 AromaticContact NE2-CE1 3.98Å; H133-F597 AromaticContact NE2-CZ 3.86Å; H133-T649 HydrophobicContact CB-CG2 3.57Å
134G89.7Confident88.8Confident23 Ų2364.8 Ų64.824%0.23734%0.335CS..G310 helixtrans-59.5-28.6-177.500000113.4Y132 M136 F137Y132-G134 VanDerWaalsContact CZ-CA 3.49Å; G134-M136 PolarHBondContact O-N 2.99Å; G134-M136 VanDerWaalsContact O-N 3.16Å; G134-F137 PolarHBondContact O-N 3.46Å
135W90.8Very high88.7Confident19 Ų1962 Ų627%0.07234%0.341CS..G310 helixtrans-58-25.2174.664.7-93.4000114.1Y132 H133 F137 T147 W150 L296 L297 V301 L596Y132-W135 HydrophobicContact CE1-CB 4.4Å; Y132-W135 VanDerWaalsContact O-CD1 3.24Å; Y132-W135 PolarHBondContact O-NE1 3.41Å; Y132-W135 VanDerWaalsContact O-NE1 3.14Å; H133-W135 PolarHBondContact O-N 3.39Å; H133-W135 VanDerWaalsContact O-N 3.15Å; W135-F137 PolarHBondContact O-N 3.01Å; W135-T147 HydrophobicContact CB-CG2 3.59Å; W135-W150 HydrophobicContact CB-CE3 4.45Å; W135-W150 HydrophobicContact CB-CZ3 4.03Å; W135-W150 AromaticContact CD1-CH2 3.23Å; W135-W150 AromaticContact CD1-CZ2 3.76Å; W135-W150 AromaticContact CD1-CZ3 3.55Å; W135-W150 HydrophobicContact CD2-CH2 4.25Å; W135-W150 HydrophobicContact CD2-CZ3 4.36Å; W135-W150 HydrophobicContact CG-CE3 4.5Å; W135-W150 AromaticContact CG-CH2 3.81Å; W135-W150 HydrophobicContact CG-CH2 3.81Å; W135-W150 AromaticContact CG-CZ3 3.72Å; W135-W150 HydrophobicContact CG-CZ3 3.72Å; W135-W150 AromaticContact NE1-CH2 3.38Å; W135-W150 AromaticContact NE1-CZ2 3.89Å; W135-L296 HydrophobicContact CH2-CD1 4.3Å; W135-L297 HydrophobicContact CD2-CD2 4.44Å; W135-L297 HydrophobicContact CE3-CD1 4.48Å; W135-L297 HydrophobicContact CE3-CD2 4.07Å; W135-V301 HydrophobicContact CH2-CG2 4.42Å; W135-V301 HydrophobicContact CZ2-CB 4.35Å; W135-V301 HydrophobicContact CZ2-CG1 3.96Å; W135-V301 HydrophobicContact CZ2-CG2 4Å; W135-L596 HydrophobicContact CZ2-CD2 4.22Å
136M90.5Very high88.5Confident31 Ų3163.6 Ų63.615%0.15335%0.352CS..G310 helixtrans-68.3-21.1174.8-76-74-77.600112.2H133 G134 R645 M648 T649H133-M136 WeakPolarHBondContact O-CB 3.31Å; H133-M136 PolarHBondContact O-N 3.37Å; G134-M136 PolarHBondContact O-N 2.99Å; G134-M136 VanDerWaalsContact O-N 3.16Å; M136-R645 HydrophobicContact CE-CB 4.45Å; M136-R645 HydrophobicContact CE-CG 4.04Å; M136-R645 WeakPolarHBondContact O-CD 3.28Å; M136-M648 HydrophobicContact CE-CB 4.03Å; M136-M648 HydrophobicContact CE-CE 3.94Å; M136-M648 HydrophobicContact CE-CG 4.36Å; M136-M648 HydrophobicContact CE-SD 3.47Å; M136-M648 WeakPolarHBondContact CE-SD 3.2Å; M136-T649 HydrophobicContact CB-CG2 4.41Å; M136-T649 HydrophobicContact CG-CG2 4.17Å
137F90.6Very high88.3Confident82 Ų8263.6 Ų63.636%0.3635%0.352SS..G310 helixtrans-100.1-4.2-175.6-59.1-86.1000113.4G134 W135 L642 R645 L646 T649G134-F137 PolarHBondContact O-N 3.46Å; W135-F137 PolarHBondContact O-N 3.01Å; F137-L642 HydrophobicContact CD1-CD1 4.41Å; F137-L642 HydrophobicContact CE1-CD1 4.07Å; F137-R645 HydrophobicContact CE1-CB 3.96Å; F137-R645 HydrophobicContact CZ-CB 4.25Å; F137-L646 HydrophobicContact CE1-CD2 4.39Å; F137-L646 HydrophobicContact CZ-CD2 4.28Å; F137-T649 HydrophobicContact CE2-CG2 4.37Å
138D85.4Confident88.1Confident40 Ų4067 Ų6721%0.21437%0.367CS..SBendtrans-62.1149.7171-79.9-8.9000110.9H140 S144 T147D138-H140 PolarHBondContact O-N 2.83Å; D138-S144 PolarHBondContact OD1-OG 2.95Å; D138-S144 PolarHBondContact OD2-N 3.35Å; D138-S144 VanDerWaalsContact OD2-N 3.13Å; D138-S144 PolarHBondContact OD2-OG 3.31Å; D138-T147 VanDerWaalsContact OD2-CB 3.23Å; D138-T147 WeakPolarHBondContact OD2-CB 3.32Å; D138-T147 PolarHBondContact OD2-OG1 2.71Å
139E76.2Confident88.1Confident131 Ų13169.7 Ų69.761%0.61238%0.377SS*.PPolyproline II helixtrans-60.2138.1174.5-75.4-173.8179.200111G141 K142E139-G141 PolarHBondContact O-N 3.29Å; E139-K142 HydrophobicContact CB-CB 4.28Å; E139-K142 CarbonylContact O-C 3.58Å; E139-K142 PolarHBondContact O-N 3.36Å; E139-K142 IonicContact OE2-NZ 3.88Å; E139-K142 PolarHBondContact OE2-NZ 2.78Å
140H69.4Low88Confident199 Ų19969.1 Ų69.192%0.92137%0.373SS*.THydrogen-bonded Turntrans-57.9127.5179.1-166.876.7000111.1D138 K142D138-H140 PolarHBondContact O-N 2.83Å; H140-K142 VanDerWaalsContact C-N 3.27Å; H140-K142 PolarHBondContact O-N 2.82Å
141G69.5Low87.9Confident76 Ų7669.9 Ų69.978%0.78438%0.376SS*.THydrogen-bonded Turntrans81-5.6-17800000115.4E139E139-G141 PolarHBondContact O-N 3.29Å
142K81.4Confident87.8Confident141 Ų14170.2 Ų70.261%0.61338%0.382SS*.  trans-126.886.6178.1-65.5-178.3-166.3160.70111E139 H140 S144E139-K142 HydrophobicContact CB-CB 4.28Å; E139-K142 CarbonylContact O-C 3.58Å; E139-K142 PolarHBondContact O-N 3.36Å; E139-K142 IonicContact OE2-NZ 3.88Å; E139-K142 PolarHBondContact OE2-NZ 2.78Å; H140-K142 VanDerWaalsContact C-N 3.27Å; H140-K142 PolarHBondContact O-N 2.82Å; K142-S144 PolarHBondContact O-N 3.48Å
143L84.5Confident87.8Confident61 Ų6168.3 Ų68.332%0.31938%0.377SS..  trans-71.4129172.4-61.2175.2000110.4T147 K148 M151 L297L143-T147 HydrophobicContact CB-CG2 4.43Å; L143-T147 HydrophobicContact CD2-CG2 3.97Å; L143-K148 HydrophobicContact CB-CG 4.05Å; L143-K148 WeakPolarHBondContact O-CE 3.44Å; L143-M151 HydrophobicContact CD1-SD 3.8Å; L143-L297 HydrophobicContact CD2-CD1 4.24Å
144S89.1Confident87.9Confident36 Ų3667 Ų6725%0.25237%0.371SS..  trans-62.7155.6174.562.30000111.2D138 K142 S146 T147 K148D138-S144 PolarHBondContact OD1-OG 2.95Å; D138-S144 PolarHBondContact OD2-N 3.35Å; D138-S144 VanDerWaalsContact OD2-N 3.13Å; D138-S144 PolarHBondContact OD2-OG 3.31Å; K142-S144 PolarHBondContact O-N 3.48Å; S144-S146 PolarHBondContact O-N 2.78Å; S144-S146 PolarHBondContact OG-OG 3.13Å; S144-T147 PolarHBondContact O-N 3.1Å; S144-T147 VanDerWaalsContact O-N 3.17Å; S144-T147 WeakPolarHBondContact OG-CB 3.2Å; S144-T147 PolarHBondContact OG-N 3.19Å; S144-T147 PolarHBondContact OG-OG1 3.01Å; S144-K148 WeakPolarHBondContact O-CG 3.25Å; S144-K148 PolarHBondContact O-N 3.31Å
145A90.3Very high88Confident84 Ų8471.2 Ų71.269%0.69438%0.383SS*.Hα-helixtrans-60.5-36.2177.500000111.7K148 F149A145-K148 PolarHBondContact O-N 3.34Å; A145-F149 WeakPolarHBondContact O-CB 3.44Å; A145-F149 PolarHBondContact O-N 3.12Å
146S90Very high87.9Confident71 Ų7176.3 Ų76.350%0.49741%0.411SS..Hα-helixtrans-61.6-46.5172.646.50000111.9S144 K148 F149 W150S144-S146 PolarHBondContact O-N 2.78Å; S144-S146 PolarHBondContact OG-OG 3.13Å; S146-K148 PolarHBondContact O-N 3.1Å; S146-F149 PolarHBondContact O-N 2.97Å; S146-W150 WeakPolarHBondContact O-CB 3.39Å; S146-W150 PolarHBondContact O-N 2.96Å
147T92.1Very high87.9Confident0 Ų077.6 Ų77.60%042%0.416CS..Hα-helixtrans-61.8-43.2175.7-66.60000111.3W135 D138 L143 S144 F149 W150 M151W135-T147 HydrophobicContact CB-CG2 3.59Å; D138-T147 VanDerWaalsContact OD2-CB 3.23Å; D138-T147 WeakPolarHBondContact OD2-CB 3.32Å; D138-T147 PolarHBondContact OD2-OG1 2.71Å; L143-T147 HydrophobicContact CB-CG2 4.43Å; L143-T147 HydrophobicContact CD2-CG2 3.97Å; S144-T147 PolarHBondContact O-N 3.1Å; S144-T147 VanDerWaalsContact O-N 3.17Å; S144-T147 WeakPolarHBondContact OG-CB 3.2Å; S144-T147 PolarHBondContact OG-N 3.19Å; S144-T147 PolarHBondContact OG-OG1 3.01Å; T147-F149 PolarHBondContact O-N 2.93Å; T147-W150 HydrophobicContact CG2-CE3 4.28Å; T147-W150 PolarHBondContact O-N 3.38Å; T147-M151 HydrophobicContact CG2-CG 4.31Å; T147-M151 HydrophobicContact CG2-SD 4.25Å; T147-M151 WeakPolarHBondContact O-CB 3.45Å; T147-M151 VanDerWaalsContact O-CG 3.25Å; T147-M151 WeakPolarHBondContact O-CG 3.23Å; T147-M151 PolarHBondContact O-N 2.89Å
148K91.7Very high87.8Confident126 Ų12674.8 Ų74.855%0.54841%0.407SS..Hα-helixtrans-61.2-43.6176.9-69.7174.8-176.7173.30112.1L143 S144 A145 S146 M151 A152L143-K148 HydrophobicContact CB-CG 4.05Å; L143-K148 WeakPolarHBondContact O-CE 3.44Å; S144-K148 WeakPolarHBondContact O-CG 3.25Å; S144-K148 PolarHBondContact O-N 3.31Å; A145-K148 PolarHBondContact O-N 3.34Å; S146-K148 PolarHBondContact O-N 3.1Å; K148-M151 PolarHBondContact O-N 2.81Å; K148-A152 PolarHBondContact O-N 3.27Å
149F93.9Very high87.6Confident141 Ų14173.8 Ų73.862%0.61841%0.406SS*.Hα-helixtrans-63.8-46.2175.8-179.8-106.8000111.6A145 S146 T147 M151 A152 L153A145-F149 WeakPolarHBondContact O-CB 3.44Å; A145-F149 PolarHBondContact O-N 3.12Å; S146-F149 PolarHBondContact O-N 2.97Å; T147-F149 PolarHBondContact O-N 2.93Å; F149-M151 VanDerWaalsContact C-N 3.35Å; F149-M151 PolarHBondContact O-N 3.02Å; F149-A152 WeakPolarHBondContact O-CB 3.48Å; F149-A152 PolarHBondContact O-N 3.46Å; F149-A152 VanDerWaalsContact O-N 3.16Å; F149-L153 HydrophobicContact CD1-CD1 4.03Å; F149-L153 HydrophobicContact CE1-CD1 3.55Å; F149-L153 HydrophobicContact CE1-CG 4.17Å; F149-L153 HydrophobicContact CZ-CD1 4.02Å; F149-L153 HydrophobicContact CZ-CD2 4.32Å; F149-L153 HydrophobicContact CZ-CG 4.27Å; F149-L153 PolarHBondContact O-N 2.78Å
150W95.2Very high87.7Confident17 Ų1779.4 Ų79.46%0.06442%0.422CS..Hα-helixtrans-57.9-44.3173.916684.3000112.2L129 Y132 W135 S146 T147 A152 L153 V154 L297 V301L129-W150 PolarHBondContact O-NE1 2.68Å; Y132-W150 AromaticContact CD1-CD1 3.82Å; Y132-W150 AromaticContact CD1-CD2 3.89Å; Y132-W150 HydrophobicContact CD1-CD2 3.89Å; Y132-W150 AromaticContact CD1-CE2 3.81Å; Y132-W150 AromaticContact CD1-CG 3.91Å; Y132-W150 HydrophobicContact CD1-CG 3.91Å; Y132-W150 HydrophobicContact CD1-CZ2 4.38Å; Y132-W150 AromaticContact CD1-NE1 3.74Å; Y132-W150 HydrophobicContact CE1-CD2 4.37Å; Y132-W150 HydrophobicContact CE1-CG 4.34Å; W135-W150 HydrophobicContact CB-CE3 4.45Å; W135-W150 HydrophobicContact CB-CZ3 4.03Å; W135-W150 AromaticContact CD1-CH2 3.23Å; W135-W150 AromaticContact CD1-CZ2 3.76Å; W135-W150 AromaticContact CD1-CZ3 3.55Å; W135-W150 HydrophobicContact CD2-CH2 4.25Å; W135-W150 HydrophobicContact CD2-CZ3 4.36Å; W135-W150 HydrophobicContact CG-CE3 4.5Å; W135-W150 AromaticContact CG-CH2 3.81Å; W135-W150 HydrophobicContact CG-CH2 3.81Å; W135-W150 AromaticContact CG-CZ3 3.72Å; W135-W150 HydrophobicContact CG-CZ3 3.72Å; W135-W150 AromaticContact NE1-CH2 3.38Å; W135-W150 AromaticContact NE1-CZ2 3.89Å; S146-W150 WeakPolarHBondContact O-CB 3.39Å; S146-W150 PolarHBondContact O-N 2.96Å; T147-W150 HydrophobicContact CG2-CE3 4.28Å; T147-W150 PolarHBondContact O-N 3.38Å; W150-A152 VanDerWaalsContact C-N 3.3Å; W150-A152 PolarHBondContact O-N 3.46Å; W150-L153 WeakPolarHBondContact O-CB 3.19Å; W150-L153 PolarHBondContact O-N 2.83Å; W150-L153 VanDerWaalsContact O-N 3.13Å; W150-V154 HydrophobicContact CD2-CG2 4.03Å; W150-V154 VanDerWaalsContact CE2-CG2 3.49Å; W150-V154 HydrophobicContact CG-CG2 4.46Å; W150-V154 HydrophobicContact CH2-CG2 4.4Å; W150-V154 HydrophobicContact CZ2-CG2 3.72Å; W150-V154 WeakPolarHBondContact O-CG2 3.32Å; W150-V154 PolarHBondContact O-N 3.13Å; W150-L297 HydrophobicContact CZ3-CD2 4.17Å; W150-V301 HydrophobicContact CH2-CG2 3.52Å; W150-V301 HydrophobicContact CZ2-CG2 4.44Å; W150-V301 HydrophobicContact CZ3-CG2 4.24Å
151M93.8Very high88.5Confident24 Ų2478.9 Ų78.912%0.11842%0.416CS..Hα-helixtrans-59.9-40.9176-73177.274.300111.7L143 T147 K148 F149 L153 V154 K155 L297 T300L143-M151 HydrophobicContact CD1-SD 3.8Å; T147-M151 HydrophobicContact CG2-CG 4.31Å; T147-M151 HydrophobicContact CG2-SD 4.25Å; T147-M151 WeakPolarHBondContact O-CB 3.45Å; T147-M151 VanDerWaalsContact O-CG 3.25Å; T147-M151 WeakPolarHBondContact O-CG 3.23Å; T147-M151 PolarHBondContact O-N 2.89Å; K148-M151 PolarHBondContact O-N 2.81Å; F149-M151 VanDerWaalsContact C-N 3.35Å; F149-M151 PolarHBondContact O-N 3.02Å; M151-L153 VanDerWaalsContact C-N 3.33Å; M151-V154 PolarHBondContact O-N 3.36Å; M151-K155 WeakPolarHBondContact O-CB 3.44Å; M151-K155 WeakPolarHBondContact O-CG 3.16Å; M151-K155 PolarHBondContact O-N 2.92Å; M151-L297 HydrophobicContact CE-CD2 3.69Å; M151-L297 HydrophobicContact CE-CG 3.75Å; M151-L297 HydrophobicContact CG-CD2 3.92Å; M151-L297 HydrophobicContact SD-CD2 3.5Å; M151-L297 VanDerWaalsContact SD-CD2 3.5Å; M151-L297 HydrophobicContact SD-CG 4.11Å; M151-T300 HydrophobicContact CB-CG2 4.09Å; M151-T300 HydrophobicContact CE-CG2 4.31Å; M151-T300 VanDerWaalsContact CE-OG1 3.29Å; M151-T300 WeakPolarHBondContact CE-OG1 3.24Å; M151-T300 HydrophobicContact CG-CG2 4.09Å
152A92.9Very high89.5Confident57 Ų5777.1 Ų77.147%0.47139%0.391SS..Hα-helixtrans-62.4-41.7175.800000111.3K148 F149 W150 K155 L156K148-A152 PolarHBondContact O-N 3.27Å; F149-A152 WeakPolarHBondContact O-CB 3.48Å; F149-A152 PolarHBondContact O-N 3.46Å; F149-A152 VanDerWaalsContact O-N 3.16Å; W150-A152 VanDerWaalsContact C-N 3.3Å; W150-A152 PolarHBondContact O-N 3.46Å; A152-K155 PolarHBondContact O-N 3.29Å; A152-L156 WeakPolarHBondContact O-CB 3.43Å; A152-L156 PolarHBondContact O-N 2.9Å
153L94.4Very high90.2Very high48 Ų4872 Ų7225%0.25137%0.37SS..Hα-helixtrans-63.5-47.2173.4-66.2178.7000112L129 F149 W150 M151 K155 L156 F157L129-L153 HydrophobicContact CD1-CB 4.04Å; L129-L153 HydrophobicContact CD2-CB 3.96Å; L129-L153 HydrophobicContact CD2-CD1 4.16Å; F149-L153 HydrophobicContact CD1-CD1 4.03Å; F149-L153 HydrophobicContact CE1-CD1 3.55Å; F149-L153 HydrophobicContact CE1-CG 4.17Å; F149-L153 HydrophobicContact CZ-CD1 4.02Å; F149-L153 HydrophobicContact CZ-CD2 4.32Å; F149-L153 HydrophobicContact CZ-CG 4.27Å; F149-L153 PolarHBondContact O-N 2.78Å; W150-L153 WeakPolarHBondContact O-CB 3.19Å; W150-L153 PolarHBondContact O-N 2.83Å; W150-L153 VanDerWaalsContact O-N 3.13Å; M151-L153 VanDerWaalsContact C-N 3.33Å; L153-K155 VanDerWaalsContact C-N 3.26Å; L153-K155 PolarHBondContact O-N 2.72Å; L153-L156 WeakPolarHBondContact O-CB 3.28Å; L153-L156 PolarHBondContact O-N 2.98Å; L153-L156 VanDerWaalsContact O-N 3.09Å; L153-F157 VanDerWaalsContact O-CD2 3.3Å; L153-F157 WeakPolarHBondContact O-CD2 3.45Å; L153-F157 PolarHBondContact O-N 3.08Å
154V94.2Very high90.6Very high0 Ų069.2 Ų69.20%036%0.355CS..Hα-helixtrans-55.8-45176.4173.10000110.3L126 L129 L130 W150 M151 F157 S158 T300L126-V154 HydrophobicContact CD1-CG1 4.3Å; L129-V154 HydrophobicContact CB-CG2 3.9Å; L129-V154 HydrophobicContact CD1-CG2 4.5Å; L130-V154 HydrophobicContact CD2-CG1 4.18Å; W150-V154 HydrophobicContact CD2-CG2 4.03Å; W150-V154 VanDerWaalsContact CE2-CG2 3.49Å; W150-V154 HydrophobicContact CG-CG2 4.46Å; W150-V154 HydrophobicContact CH2-CG2 4.4Å; W150-V154 HydrophobicContact CZ2-CG2 3.72Å; W150-V154 WeakPolarHBondContact O-CG2 3.32Å; W150-V154 PolarHBondContact O-N 3.13Å; M151-V154 PolarHBondContact O-N 3.36Å; V154-F157 PolarHBondContact O-N 2.95Å; V154-S158 WeakPolarHBondContact O-CB 3.42Å; V154-S158 PolarHBondContact O-N 3.26Å; V154-S158 PolarHBondContact O-OG 3.36Å; V154-T300 HydrophobicContact CB-CG2 3.96Å; V154-T300 HydrophobicContact CG1-CG2 3.79Å; V154-T300 WeakPolarHBondContact CG1-O 3.5Å
155K91.1Very high91Very high111 Ų11169.1 Ų69.148%0.48335%0.35SS..Hα-helixtrans-65-38.4177-73.1179-179.6-177.30112.9M151 A152 L153 S158 T300M151-K155 WeakPolarHBondContact O-CB 3.44Å; M151-K155 WeakPolarHBondContact O-CG 3.16Å; M151-K155 PolarHBondContact O-N 2.92Å; A152-K155 PolarHBondContact O-N 3.29Å; L153-K155 VanDerWaalsContact C-N 3.26Å; L153-K155 PolarHBondContact O-N 2.72Å; K155-S158 PolarHBondContact O-N 3.16Å; K155-S158 VanDerWaalsContact O-O 3.13Å; K155-T300 WeakPolarHBondContact CE-OG1 3.36Å; K155-T300 HydrophobicContact CG-CG2 4.32Å
156L90.3Very high91.1Very high127 Ų12765.2 Ų65.267%0.66532%0.317SS*.Hα-helixtrans-64.1-43177-179.966.1000111.8A152 L153A152-L156 WeakPolarHBondContact O-CB 3.43Å; A152-L156 PolarHBondContact O-N 2.9Å; L153-L156 WeakPolarHBondContact O-CB 3.28Å; L153-L156 PolarHBondContact O-N 2.98Å; L153-L156 VanDerWaalsContact O-N 3.09Å
157F89.9Confident91.4Very high57 Ų5762.1 Ų62.125%0.2530%0.295CS..Hα-helixtrans-84.3-10.3179.5-76.3-85.4000113.3P56 L126 L129 L153 V154P56-F157 WeakPolarHBondContact CB-O 3.38Å; P56-F157 WeakPolarHBondContact CG-O 3.45Å; L126-F157 HydrophobicContact CB-CB 4.38Å; L126-F157 HydrophobicContact CD1-CB 4.27Å; L129-F157 HydrophobicContact CD1-CB 4.19Å; L129-F157 HydrophobicContact CD1-CD2 3.77Å; L129-F157 HydrophobicContact CD1-CG 4.16Å; L153-F157 VanDerWaalsContact O-CD2 3.3Å; L153-F157 WeakPolarHBondContact O-CD2 3.45Å; L153-F157 PolarHBondContact O-N 3.08Å; V154-F157 PolarHBondContact O-N 2.95Å
158S87.8Confident91.4Very high24 Ų2462.9 Ų62.917%0.16830%0.299CS..SBendtrans-85.1122.7172.2-640000110.1V154 K155V154-S158 WeakPolarHBondContact O-CB 3.42Å; V154-S158 PolarHBondContact O-N 3.26Å; V154-S158 PolarHBondContact O-OG 3.36Å; K155-S158 PolarHBondContact O-N 3.16Å; K155-S158 VanDerWaalsContact O-O 3.13Å
159G81.5Confident91.4Very high19 Ų1959.1 Ų59.120%0.19629%0.286CS..  trans-62.2153.8175.500000112.9Y55 K161Y55-G159 PolarHBondContact OH-N 3.04Å; Y55-G159 PolarHBondContact OH-O 3.01Å; Y55-G159 VanDerWaalsContact OH-O 3.06Å; G159-K161 PolarHBondContact O-N 3.27Å
160R78.9Confident91.4Very high249 Ų24952.4 Ų52.494%0.9426%0.257SS*.SBendtrans-71.6-16.1-167-63.5-177.4-179.8177.8-0.3116.6
161K85.3Confident91.4Very high187 Ų18751.8 Ų51.881%0.81326%0.255SS*.SBendtrans-14374.1-176-66-174.3-179.4-1790111.1G159G159-K161 PolarHBondContact O-N 3.27Å
162P91.8Very high91.5Very high40 Ų4050.8 Ų50.826%0.2625%0.25SC..  trans-70.9137.9179.431.2-34.9000110.9Y55 F167 P293Y55-P162 HydrophobicContact CE2-CB 4.12Å; P162-F167 HydrophobicContact CB-CD2 4.14Å; P162-F167 HydrophobicContact CB-CE2 3.43Å; P162-F167 VanDerWaalsContact CB-CE2 3.43Å; P162-F167 HydrophobicContact CB-CZ 4.03Å; P162-F167 HydrophobicContact CG-CE2 3.83Å; P162-F167 HydrophobicContact CG-CZ 4.29Å; P162-P293 HydrophobicContact CB-CG 4.03Å; P162-P293 HydrophobicContact CG-CG 3.99Å
163M94.4Very high91.6Very high34 Ų3453.2 Ų53.217%0.16725%0.247CC..  trans-88.4170.3165.9-56.6-176.171.400109.5N48 I51 T52 Y165 S166 R288 Q289N48-M163 HydrophobicContact CB-CE 3.91Å; N48-M163 HydrophobicContact CB-SD 4.42Å; N48-M163 WeakPolarHBondContact ND2-CE 3.25Å; N48-M163 VanDerWaalsContact OD1-CE 3.32Å; N48-M163 WeakPolarHBondContact OD1-CE 3.41Å; I51-M163 HydrophobicContact CB-SD 4.21Å; I51-M163 HydrophobicContact CG2-SD 3.73Å; T52-M163 HydrophobicContact CG2-CB 4.01Å; T52-M163 HydrophobicContact CG2-SD 4.27Å; M163-Y165 PolarHBondContact O-N 2.89Å; M163-S166 PolarHBondContact N-OG 3.33Å; M163-S166 WeakPolarHBondContact O-CB 3.46Å; M163-S166 PolarHBondContact O-N 3.48Å; M163-S166 PolarHBondContact O-OG 2.96Å; M163-R288 WeakPolarHBondContact CE-O 3.45Å; M163-Q289 HydrophobicContact CB-CB 4.31Å; M163-Q289 HydrophobicContact CE-CB 3.83Å
164L94.9Very high91.6Very high2 Ų251.5 Ų51.51%0.0124%0.238CC..THydrogen-bonded Turntrans-46.7-42.5-176.2-176.358.9000113.9L286 Q289 I291 S305 W308L164-L286 HydrophobicContact CD2-CD1 3.44Å; L164-L286 VanDerWaalsContact CD2-CD1 3.44Å; L164-Q289 HydrophobicContact CB-CB 4.04Å; L164-Q289 PolarHBondContact N-O 2.86Å; L164-I291 WeakPolarHBondContact CA-O 2.98Å; L164-I291 VanDerWaalsContact CB-O 3.31Å; L164-I291 WeakPolarHBondContact CB-O 3.49Å; L164-I291 HydrophobicContact CD1-CB 4.15Å; L164-I291 HydrophobicContact CD1-CG2 4.02Å; L164-I291 HydrophobicContact CD2-CB 4.3Å; L164-I291 PolarHBondContact N-O 3.18Å; L164-S305 WeakPolarHBondContact O-CB 3.43Å; L164-S305 PolarHBondContact O-OG 3.15Å; L164-W308 HydrophobicContact CD2-CB 4.17Å; L164-W308 HydrophobicContact CD2-CG 4.27Å
165Y95.6Very high91.7Very high34 Ų3454.1 Ų54.113%0.13326%0.255CS..THydrogen-bonded Turntrans-103.36.2-176.2-55.4-57.1000114.5M163 F167 Q168 Q289 S305 E309M163-Y165 PolarHBondContact O-N 2.89Å; Y165-F167 PolarHBondContact O-N 3.41Å; Y165-F167 VanDerWaalsContact O-N 3.15Å; Y165-Q168 HydrophobicContact CD1-CG 4.07Å; Y165-Q168 HydrophobicContact CG-CG 4.49Å; Y165-Q168 WeakPolarHBondContact O-CG 3.45Å; Y165-Q168 PolarHBondContact O-N 3.35Å; Y165-Q168 VanDerWaalsContact O-N 3.09Å; Y165-Q289 HydrophobicContact CD2-CB 4.49Å; Y165-Q289 VanDerWaalsContact CD2-CD 3.41Å; Y165-Q289 HydrophobicContact CD2-CG 3.72Å; Y165-Q289 HydrophobicContact CE2-CG 3.87Å; Y165-S305 WeakPolarHBondContact CE1-O 3.24Å; Y165-E309 HydrophobicContact CE1-CG 3.99Å; Y165-E309 WeakPolarHBondContact OH-CG 3.49Å
166S94.2Very high92Very high1 Ų150.3 Ų50.31%0.00724%0.241CC..THydrogen-bonded Turntrans-55-37-176.3-78.90000113.9Y55 M163Y55-S166 WeakPolarHBondContact CD1-O 3.35Å; M163-S166 PolarHBondContact N-OG 3.33Å; M163-S166 WeakPolarHBondContact O-CB 3.46Å; M163-S166 PolarHBondContact O-N 3.48Å; M163-S166 PolarHBondContact O-OG 2.96Å
167F94.9Very high92.3Very high6 Ų645 Ų453%0.02621%0.214CC..THydrogen-bonded Turntrans-86-9.5-177.4-66.7-77.6000114.4Y55 L126 P162 Y165 T169 S170 L171 P293 L295 P302Y55-F167 AromaticContact CE1-CD1 3.73Å; Y55-F167 HydrophobicContact CE1-CD1 3.73Å; Y55-F167 AromaticContact CE1-CE1 3.6Å; Y55-F167 HydrophobicContact CE1-CE1 3.6Å; Y55-F167 HydrophobicContact CE1-CG 4.32Å; Y55-F167 HydrophobicContact CE1-CZ 4.09Å; Y55-F167 AromaticContact CZ-CE1 3.88Å; Y55-F167 AromaticContact CZ-CZ 3.93Å; Y55-F167 WeakPolarHBondContact OH-CE1 3.34Å; Y55-F167 WeakPolarHBondContact OH-CZ 3.3Å; L126-F167 HydrophobicContact CD2-CD1 4.18Å; L126-F167 HydrophobicContact CD2-CE1 4.21Å; P162-F167 HydrophobicContact CB-CD2 4.14Å; P162-F167 HydrophobicContact CB-CE2 3.43Å; P162-F167 VanDerWaalsContact CB-CE2 3.43Å; P162-F167 HydrophobicContact CB-CZ 4.03Å; P162-F167 HydrophobicContact CG-CE2 3.83Å; P162-F167 HydrophobicContact CG-CZ 4.29Å; Y165-F167 PolarHBondContact O-N 3.41Å; Y165-F167 VanDerWaalsContact O-N 3.15Å; F167-T169 VanDerWaalsContact C-N 3.27Å; F167-T169 PolarHBondContact O-N 3.48Å; F167-T169 VanDerWaalsContact O-N 3.13Å; F167-S170 CarbonylContact O-C 3.46Å; F167-S170 WeakPolarHBondContact O-CA 3.45Å; F167-S170 PolarHBondContact O-N 3.33Å; F167-L171 WeakPolarHBondContact O-CG 3.5Å; F167-L171 PolarHBondContact O-N 2.92Å; F167-P293 HydrophobicContact CD2-CB 4.3Å; F167-P293 HydrophobicContact CD2-CG 4.24Å; F167-P293 HydrophobicContact CE2-CG 4.1Å; F167-L295 HydrophobicContact CE2-CD2 4.05Å; F167-P302 HydrophobicContact CB-CB 3.83Å; F167-P302 HydrophobicContact CB-CG 3.91Å; F167-P302 HydrophobicContact CD1-CB 4.04Å; F167-P302 HydrophobicContact CD1-CG 3.64Å; F167-P302 HydrophobicContact CD2-CB 3.57Å; F167-P302 HydrophobicContact CD2-CG 4.14Å; F167-P302 HydrophobicContact CE1-CB 4.48Å; F167-P302 HydrophobicContact CE1-CG 4.12Å; F167-P302 HydrophobicContact CE2-CB 4.06Å; F167-P302 HydrophobicContact CG-CB 3.55Å; F167-P302 HydrophobicContact CG-CG 3.64Å; F167-P302 HydrophobicContact CZ-CB 4.48Å
168Q93.7Very high92.7Very high17 Ų1744.5 Ų44.58%0.07922%0.217CC..THydrogen-bonded Turntrans-57.2-37.3-170-68-47.6-5400113.6Y165 S170 C304 R598Y165-Q168 HydrophobicContact CD1-CG 4.07Å; Y165-Q168 HydrophobicContact CG-CG 4.49Å; Y165-Q168 WeakPolarHBondContact O-CG 3.45Å; Y165-Q168 PolarHBondContact O-N 3.35Å; Y165-Q168 VanDerWaalsContact O-N 3.09Å; Q168-S170 VanDerWaalsContact C-N 3.33Å; Q168-C304 PolarHBondContact OE1-SG 2.8Å; Q168-R598 WeakPolarHBondContact O-CD 3.34Å
169T89.8Confident93.2Very high47 Ų4744 Ų4429%0.28821%0.214SC..THydrogen-bonded Turntrans-79-17.2178.5560000113.8R123 F167R123-T169 PolarHBondContact NE-OG1 2.79Å; F167-T169 VanDerWaalsContact C-N 3.27Å; F167-T169 PolarHBondContact O-N 3.48Å; F167-T169 VanDerWaalsContact O-N 3.13Å
170S94.1Very high93.9Very high0 Ų051 Ų510%024%0.239CC..THydrogen-bonded Turntrans-98.9-13.6-179.3-52.40000112.5K127 F167 Q168K127-S170 WeakPolarHBondContact CA-O 3.45Å; K127-S170 VanDerWaalsContact CB-O 3.3Å; K127-S170 WeakPolarHBondContact CB-O 3.25Å; F167-S170 CarbonylContact O-C 3.46Å; F167-S170 WeakPolarHBondContact O-CA 3.45Å; F167-S170 PolarHBondContact O-N 3.33Å; Q168-S170 VanDerWaalsContact C-N 3.33Å
171L96.1Very high94.8Very high4 Ų443 Ų432%0.02122%0.215CC..SBendtrans-65142.7175.6-73.9169.9000111.3L130 F167 P302 C304 R598L130-L171 HydrophobicContact CD1-CD2 4.47Å; F167-L171 WeakPolarHBondContact O-CG 3.5Å; F167-L171 PolarHBondContact O-N 2.92Å; L171-P302 HydrophobicContact CD2-CG 4.09Å; L171-C304 HydrophobicContact CD1-CB 3.79Å; L171-R598 HydrophobicContact CB-CB 4.04Å
172P95.7Very high95.4Very high3 Ų334.1 Ų34.12%0.01918%0.176CC..PPolyproline II helixtrans-66.2158.7174.228.7-34.5000111.3L596 F597 R598P172-L596 WeakPolarHBondContact CD-O 3.29Å; P172-L596 WeakPolarHBondContact CG-O 3.17Å; P172-F597 HydrophobicContact CB-CD1 4.07Å; P172-F597 HydrophobicContact CB-CE1 4.42Å; P172-F597 HydrophobicContact CG-CD1 3.74Å; P172-F597 HydrophobicContact CG-CE1 4.11Å; P172-F597 WeakPolarHBondContact O-CA 3.38Å; P172-R598 PolarHBondContact O-N 2.93Å
173R94.2Very high95.7Very high107 Ų10732.7 Ų32.740%0.40417%0.166SC..PPolyproline II helixtrans-80.4149.4167.7-61.7-173.8-177.7167.7-2.5108.6S225 W226 T229 F597R173-S225 PolarHBondContact NH1-O 3.33Å; R173-W226 PolarHBondContact NH1-O 3.34Å; R173-T229 WeakPolarHBondContact CG-O 3.41Å; R173-F597 VanDerWaalsContact O-CD1 3.26Å; R173-F597 WeakPolarHBondContact O-CD1 3.19Å
174L95.8Very high95.9Very high12 Ų1237.1 Ų37.16%0.06319%0.185CC..PPolyproline II helixtrans-59.9125.1174.2-17371.4000109.4Y231 V232 T594 F597L174-Y231 HydrophobicContact CB-CD1 4.32Å; L174-Y231 HydrophobicContact CB-CE1 4.06Å; L174-Y231 HydrophobicContact CD2-CD1 4.38Å; L174-Y231 HydrophobicContact CD2-CE1 3.73Å; L174-Y231 HydrophobicContact CG-CE1 3.79Å; L174-Y231 WeakPolarHBondContact O-CD1 3.36Å; L174-Y231 WeakPolarHBondContact O-CE1 3.39Å; L174-V232 HydrophobicContact CD2-CB 4.12Å; L174-V232 HydrophobicContact CD2-CG2 3.55Å; L174-T594 HydrophobicContact CD1-CG2 4.31Å; L174-F597 HydrophobicContact CB-CB 4.05Å; L174-F597 HydrophobicContact CB-CD2 4.49Å; L174-F597 HydrophobicContact CB-CG 4.12Å; L174-F597 HydrophobicContact CD1-CB 4.24Å; L174-F597 HydrophobicContact CD1-CD2 3.24Å; L174-F597 HydrophobicContact CD1-CE2 3.63Å; L174-F597 HydrophobicContact CD1-CG 3.74Å; L174-F597 HydrophobicContact CD1-CZ 4.42Å; L174-F597 HydrophobicContact CG-CD2 4.43Å
175P95.9Very high96Very high56 Ų5639 Ų3936%0.36419%0.191SC..PPolyproline II helixtrans-70.1149.9179.229.1-35.9000110.9P177 Y231 F597P175-P177 WeakPolarHBondContact O-CD 3.48Å; P175-Y231 VanDerWaalsContact O-CE1 3.24Å; P175-Y231 WeakPolarHBondContact O-CE1 3.38Å; P175-Y231 PolarHBondContact O-OH 3.25Å; P175-F597 HydrophobicContact CG-CE1 4.27Å; P175-F597 HydrophobicContact CG-CZ 4.16Å
176V97.1Very high96.1Very high30 Ų3037.3 Ų37.318%0.18219%0.185CC..  trans-90.9113.5170.6-167.70000108.1L221 Y231V176-L221 HydrophobicContact CG1-CB 4.49Å; V176-L221 HydrophobicContact CG1-CD2 3.72Å; V176-L221 HydrophobicContact CG1-CG 3.89Å; V176-Y231 HydrophobicContact CB-CE1 4.48Å; V176-Y231 HydrophobicContact CG2-CD1 3.86Å; V176-Y231 HydrophobicContact CG2-CE1 3.87Å; V176-Y231 HydrophobicContact CG2-CG 4.21Å
177P97Very high96.3Very high16 Ų1638.2 Ų38.210%0.10419%0.189CC..  trans-61.7165.3177.5-20.932.7000112.2P175 Q218 Y231 G650 H656P175-P177 WeakPolarHBondContact O-CD 3.48Å; P177-Q218 PolarHBondContact O-NE2 3.03Å; P177-Q218 PolarHBondContact O-OE1 3.1Å; P177-Y231 WeakPolarHBondContact CD-OH 3.33Å; P177-G650 WeakPolarHBondContact CG-O 3.48Å; P177-H656 HydrophobicContact CG-CB 4.24Å; P177-H656 PolarHBondContact O-CE1 3.27Å
178S97.6Very high96.4Very high46 Ų4641.7 Ų41.732%0.32221%0.206SC..  trans-76146.3169.988.20000110.7K180 D181 T182S178-K180 VanDerWaalsContact C-N 3.28Å; S178-K180 PolarHBondContact O-N 3.31Å; S178-D181 PolarHBondContact O-N 3.43Å; S178-D181 WeakPolarHBondContact OG-CB 3.32Å; S178-D181 PolarHBondContact OG-N 3.14Å; S178-D181 PolarHBondContact OG-OD2 3.12Å; S178-T182 WeakPolarHBondContact O-CB 3.5Å; S178-T182 PolarHBondContact O-N 3.46Å; S178-T182 VanDerWaalsContact O-N 3.09Å; S178-T182 PolarHBondContact O-OG1 3.06Å
179V98.1Very high96.5Very high14 Ų1441.4 Ų41.49%0.08521%0.206CC..Hα-helixtrans-58.1-44.7173.5-179.80000110.3D181 T182 V183 F209 A210 Q218V179-D181 PolarHBondContact O-N 3.35Å; V179-T182 PolarHBondContact O-N 3.02Å; V179-V183 HydrophobicContact CG1-CG2 4.03Å; V179-V183 WeakPolarHBondContact O-CB 3.39Å; V179-V183 WeakPolarHBondContact O-CG2 3.34Å; V179-V183 PolarHBondContact O-N 3.36Å; V179-F209 HydrophobicContact CG1-CD1 4.26Å; V179-F209 HydrophobicContact CG1-CE1 3.92Å; V179-A210 HydrophobicContact CG1-CB 4.22Å; V179-Q218 HydrophobicContact CG2-CB 3.79Å; V179-Q218 HydrophobicContact CG2-CG 4.11Å
180K97.4Very high96.8Very high166 Ų16639.2 Ų39.272%0.72219%0.192SC*.Hα-helixtrans-57.5-48.4-178.9-175.5-179.8178.4-179.50112.3S178 T182 K184S178-K180 VanDerWaalsContact C-N 3.28Å; S178-K180 PolarHBondContact O-N 3.31Å; K180-T182 VanDerWaalsContact C-N 3.34Å; K180-K184 WeakPolarHBondContact O-CB 3.37Å; K180-K184 PolarHBondContact O-N 3.44Å
181D97.1Very high96.9Very high82 Ų8243.2 Ų43.244%0.43921%0.207SC..Hα-helixtrans-70.4-35.1-179.2-59.6-37.4000111.6S178 V179 R185S178-D181 PolarHBondContact O-N 3.43Å; S178-D181 WeakPolarHBondContact OG-CB 3.32Å; S178-D181 PolarHBondContact OG-N 3.14Å; S178-D181 PolarHBondContact OG-OD2 3.12Å; V179-D181 PolarHBondContact O-N 3.35Å; D181-R185 WeakPolarHBondContact O-CB 3.41Å; D181-R185 VanDerWaalsContact O-CG 3.28Å; D181-R185 WeakPolarHBondContact O-CG 3.49Å; D181-R185 PolarHBondContact O-N 2.93Å; D181-R185 PolarHBondContact O-NE 2.74Å
182T98.1Very high96.9Very high0 Ų044 Ų440%021%0.213CC..Hα-helixtrans-65.5-49.3176.8-56.60000110.8S178 V179 K180 R185 Y186 I653 H656 L657S178-T182 WeakPolarHBondContact O-CB 3.5Å; S178-T182 PolarHBondContact O-N 3.46Å; S178-T182 VanDerWaalsContact O-N 3.09Å; S178-T182 PolarHBondContact O-OG1 3.06Å; V179-T182 PolarHBondContact O-N 3.02Å; K180-T182 VanDerWaalsContact C-N 3.34Å; T182-R185 PolarHBondContact O-N 3.31Å; T182-Y186 WeakPolarHBondContact O-CB 3.09Å; T182-Y186 PolarHBondContact O-N 3.24Å; T182-I653 HydrophobicContact CG2-CG2 4.26Å; T182-H656 HydrophobicContact CG2-CB 4.23Å; T182-H656 PolarHBondContact OG1-ND1 3.49Å; T182-L657 HydrophobicContact CG2-CD2 3.73Å; T182-L657 HydrophobicContact CG2-CG 3.81Å
183V98.1Very high96.9Very high9 Ų946.1 Ų46.16%0.05522%0.224CC..Hα-helixtrans-62.6-44.1177.7166.10000111.4V179 R185 Y186 L187 A206 F209 A210 F673V179-V183 HydrophobicContact CG1-CG2 4.03Å; V179-V183 WeakPolarHBondContact O-CB 3.39Å; V179-V183 WeakPolarHBondContact O-CG2 3.34Å; V179-V183 PolarHBondContact O-N 3.36Å; V183-R185 PolarHBondContact O-N 3.03Å; V183-Y186 PolarHBondContact O-N 3.38Å; V183-L187 HydrophobicContact CG1-CD1 4.08Å; V183-L187 WeakPolarHBondContact O-CG 3.31Å; V183-L187 PolarHBondContact O-N 2.86Å; V183-A206 HydrophobicContact CG1-CB 3.74Å; V183-F209 HydrophobicContact CG2-CD1 4.2Å; V183-A210 HydrophobicContact CG2-CB 4.3Å; V183-F673 HydrophobicContact CG2-CE1 4.21Å; V183-F673 HydrophobicContact CG2-CZ 4.17Å
184K97.8Very high96.9Very high127 Ų12742.2 Ų42.255%0.55221%0.21SC*.Hα-helixtrans-56.6-50.2175.8-180-179173.9-175.90111.4K180 L187 E188K180-K184 WeakPolarHBondContact O-CB 3.37Å; K180-K184 PolarHBondContact O-N 3.44Å; K184-L187 PolarHBondContact O-N 3.45Å; K184-E188 WeakPolarHBondContact CE-OE1 3.4Å; K184-E188 WeakPolarHBondContact O-CG 3.29Å; K184-E188 PolarHBondContact O-N 3.31Å
185R97.8Very high96.9Very high41 Ų4145.8 Ų45.816%0.15523%0.23CC..Hα-helixtrans-68.6-34.2-179.5-69.9176.5-66-175.415.9112.7D181 T182 V183 E188 S189 A651 G652 I653D181-R185 WeakPolarHBondContact O-CB 3.41Å; D181-R185 VanDerWaalsContact O-CG 3.28Å; D181-R185 WeakPolarHBondContact O-CG 3.49Å; D181-R185 PolarHBondContact O-N 2.93Å; D181-R185 PolarHBondContact O-NE 2.74Å; T182-R185 PolarHBondContact O-N 3.31Å; V183-R185 PolarHBondContact O-N 3.03Å; R185-E188 PolarHBondContact O-N 2.86Å; R185-S189 WeakPolarHBondContact O-CB 3.2Å; R185-S189 PolarHBondContact O-N 3.28Å; R185-A651 PolarHBondContact NH1-O 2.7Å; R185-A651 PolarHBondContact NH2-O 3.3Å; R185-A651 VanDerWaalsContact NH2-O 3.15Å; R185-G652 PolarHBondContact NH2-O 3Å; R185-I653 HydrophobicContact CB-CD1 3.83Å; R185-I653 HydrophobicContact CB-CG1 3.84Å
186Y97.9Very high97Very high0 Ų047.3 Ų47.30%023%0.234CC..Hα-helixtrans-58.9-52.4171.2167.5-100.8000110.8T182 V183 E188 S189 V190 M202 I653 L657 F673 V677T182-Y186 WeakPolarHBondContact O-CB 3.09Å; T182-Y186 PolarHBondContact O-N 3.24Å; V183-Y186 PolarHBondContact O-N 3.38Å; Y186-E188 VanDerWaalsContact C-N 3.33Å; Y186-E188 PolarHBondContact O-N 3.39Å; Y186-S189 WeakPolarHBondContact O-CA 3.47Å; Y186-S189 WeakPolarHBondContact O-CB 3.46Å; Y186-S189 PolarHBondContact O-N 2.81Å; Y186-S189 PolarHBondContact O-OG 2.66Å; Y186-V190 HydrophobicContact CD1-CG2 4.5Å; Y186-V190 HydrophobicContact CD2-CG1 4.01Å; Y186-V190 HydrophobicContact CE1-CG1 4.4Å; Y186-V190 HydrophobicContact CE1-CG2 3.97Å; Y186-V190 HydrophobicContact CE2-CB 4.49Å; Y186-V190 HydrophobicContact CE2-CG1 3.33Å; Y186-V190 HydrophobicContact CE2-CG2 4.39Å; Y186-V190 PolarHBondContact O-N 3.29Å; Y186-M202 HydrophobicContact CE1-CG 3.81Å; Y186-M202 HydrophobicContact CE1-SD 3.72Å; Y186-M202 WeakPolarHBondContact OH-CE 3.26Å; Y186-I653 HydrophobicContact CD2-CG2 4.48Å; Y186-L657 HydrophobicContact CD2-CD1 4.3Å; Y186-L657 HydrophobicContact CG-CD1 4.42Å; Y186-F673 AromaticContact CD1-CE2 3.68Å; Y186-F673 HydrophobicContact CD1-CE2 3.68Å; Y186-F673 AromaticContact CD1-CZ 3.76Å; Y186-F673 HydrophobicContact CD1-CZ 3.76Å; Y186-F673 AromaticContact CE1-CE2 3.55Å; Y186-F673 HydrophobicContact CE1-CE2 3.55Å; Y186-F673 HydrophobicContact CE1-CZ 4.04Å; Y186-F673 HydrophobicContact CG-CZ 4.35Å; Y186-V677 HydrophobicContact CD1-CG2 4.35Å; Y186-V677 HydrophobicContact CD2-CG1 3.69Å; Y186-V677 HydrophobicContact CD2-CG2 4.37Å; Y186-V677 HydrophobicContact CE1-CG2 3.7Å; Y186-V677 HydrophobicContact CE2-CB 4Å; Y186-V677 HydrophobicContact CE2-CG1 3.3Å; Y186-V677 HydrophobicContact CE2-CG2 3.72Å; Y186-V677 WeakPolarHBondContact OH-CG2 3.44Å
187L98Very high97Very high19 Ų1947.5 Ų47.510%0.09924%0.243CC..Hα-helixtrans-59.4-42.2178.7-69.9171.3000111.8V183 K184 S189 V190 R191 F199 M202 E203 A206V183-L187 HydrophobicContact CG1-CD1 4.08Å; V183-L187 WeakPolarHBondContact O-CG 3.31Å; V183-L187 PolarHBondContact O-N 2.86Å; K184-L187 PolarHBondContact O-N 3.45Å; L187-S189 VanDerWaalsContact C-N 3.25Å; L187-S189 PolarHBondContact O-N 2.96Å; L187-V190 PolarHBondContact O-N 3.36Å; L187-R191 PolarHBondContact O-N 3.45Å; L187-R191 VanDerWaalsContact O-N 3.16Å; L187-F199 HydrophobicContact CB-CE2 4.42Å; L187-F199 HydrophobicContact CB-CZ 4.31Å; L187-F199 HydrophobicContact CD2-CE2 4.39Å; L187-F199 VanDerWaalsContact O-CE2 3.32Å; L187-F199 WeakPolarHBondContact O-CE2 3.3Å; L187-M202 HydrophobicContact CD2-CG 4.01Å; L187-E203 HydrophobicContact CD1-CG 4.11Å; L187-E203 HydrophobicContact CD2-CB 4.44Å; L187-A206 HydrophobicContact CD1-CB 4.02Å; L187-A206 HydrophobicContact CD2-CB 3.93Å; L187-A206 HydrophobicContact CG-CB 4.17Å
188E96.9Very high97Very high80 Ų8051 Ų5137%0.37426%0.258SS..Hα-helixtrans-58.1-38.2172.3-72.5174.9-161.700112.3K184 R185 Y186 K639K184-E188 WeakPolarHBondContact CE-OE1 3.4Å; K184-E188 WeakPolarHBondContact O-CG 3.29Å; K184-E188 PolarHBondContact O-N 3.31Å; R185-E188 PolarHBondContact O-N 2.86Å; Y186-E188 VanDerWaalsContact C-N 3.33Å; Y186-E188 PolarHBondContact O-N 3.39Å; E188-K639 IonicContact OE2-NZ 3.35Å
189S96.8Very high96.9Very high11 Ų1150.6 Ų50.68%0.07725%0.25CS..Hα-helixtrans-75.5-31.9-177.378.50000114.4R185 Y186 L187 P192 R606R185-S189 WeakPolarHBondContact O-CB 3.2Å; R185-S189 PolarHBondContact O-N 3.28Å; Y186-S189 WeakPolarHBondContact O-CA 3.47Å; Y186-S189 WeakPolarHBondContact O-CB 3.46Å; Y186-S189 PolarHBondContact O-N 2.81Å; Y186-S189 PolarHBondContact O-OG 2.66Å; L187-S189 VanDerWaalsContact C-N 3.25Å; L187-S189 PolarHBondContact O-N 2.96Å; S189-P192 WeakPolarHBondContact O-CD 3.47Å; S189-R606 VanDerWaalsContact OG-CD 3.32Å; S189-R606 WeakPolarHBondContact OG-CD 3.32Å; S189-R606 PolarHBondContact OG-NH1 3.3Å
190V95.8Very high96.9Very high0 Ų057.7 Ų57.70%028%0.276CS..Hα-helixtrans-92.3-11.5-179.1-62.70000113.3Y186 L187 P192 L193 M194 F199Y186-V190 HydrophobicContact CD1-CG2 4.5Å; Y186-V190 HydrophobicContact CD2-CG1 4.01Å; Y186-V190 HydrophobicContact CE1-CG1 4.4Å; Y186-V190 HydrophobicContact CE1-CG2 3.97Å; Y186-V190 HydrophobicContact CE2-CB 4.49Å; Y186-V190 HydrophobicContact CE2-CG1 3.33Å; Y186-V190 HydrophobicContact CE2-CG2 4.39Å; Y186-V190 PolarHBondContact O-N 3.29Å; L187-V190 PolarHBondContact O-N 3.36Å; V190-P192 VanDerWaalsContact C-CD 3.43Å; V190-P192 VanDerWaalsContact C-N 3.35Å; V190-L193 WeakPolarHBondContact O-CB 3.3Å; V190-L193 PolarHBondContact O-N 3.08Å; V190-M194 HydrophobicContact CB-CE 3.99Å; V190-M194 HydrophobicContact CB-SD 4.22Å; V190-M194 HydrophobicContact CG1-CE 4.46Å; V190-M194 HydrophobicContact CG2-CE 4.14Å; V190-M194 HydrophobicContact CG2-SD 4.05Å; V190-M194 PolarHBondContact O-N 3.4Å; V190-F199 HydrophobicContact CG2-CE2 4.39Å
191R96.1Very high97Very high84 Ų8455.6 Ų55.632%0.31726%0.263SS..G310 helixtrans-49.7-45.1177.2-178.357.4-169.4142.7-2.9114.5L187 L193 M194 D196 F199 V610L187-R191 PolarHBondContact O-N 3.45Å; L187-R191 VanDerWaalsContact O-N 3.16Å; R191-L193 PolarHBondContact O-N 3.47Å; R191-M194 PolarHBondContact NH1-O 2.96Å; R191-D196 IonicContact CZ-OD1 2.91Å; R191-D196 VanDerWaalsContact CZ-OD1 3.31Å; R191-D196 IonicContact NH1-OD1 3.5Å; R191-D196 PolarHBondContact NH1-OD1 3.25Å; R191-D196 VanDerWaalsContact NH1-OD1 3.08Å; R191-D196 IonicContact NH2-OD1 2.75Å; R191-D196 PolarHBondContact NH2-OD1 2.76Å; R191-F199 HydrophobicContact CB-CD2 4.25Å; R191-F199 HydrophobicContact CB-CE2 3.77Å; R191-F199 HydrophobicContact CB-CZ 4.26Å; R191-F199 HydrophobicContact CG-CE2 4.31Å; R191-F199 HydrophobicContact CG-CZ 4.5Å; R191-V610 HydrophobicContact CB-CG2 4.23Å; R191-V610 HydrophobicContact CG-CG2 4.31Å
192P95.9Very high97Very high22 Ų2251.7 Ų51.714%0.14324%0.242CC..G310 helixtrans-73.1-9.8178.929.2-34.8000114.3S189 V190 V610 C613S189-P192 WeakPolarHBondContact O-CD 3.47Å; V190-P192 VanDerWaalsContact C-CD 3.43Å; V190-P192 VanDerWaalsContact C-N 3.35Å; P192-V610 HydrophobicContact CG-CG2 4.38Å; P192-C613 HydrophobicContact CB-CB 4.29Å; P192-C613 WeakPolarHBondContact CB-SG 3.4Å
193L95Very high97Very high47 Ų4754.8 Ų54.825%0.24626%0.257CS..G310 helixtrans-98.6-7.9-175.6-55.1177.8000113.2V190 R191 F585 L587V190-L193 WeakPolarHBondContact O-CB 3.3Å; V190-L193 PolarHBondContact O-N 3.08Å; R191-L193 PolarHBondContact O-N 3.47Å; L193-F585 HydrophobicContact CD2-CB 4.2Å; L193-L587 HydrophobicContact CD1-CB 3.95Å; L193-L587 HydrophobicContact CD1-CD1 3.71Å; L193-L587 HydrophobicContact CD1-CG 4.42Å
194M94.8Very high97Very high25 Ų2556.2 Ų56.212%0.12327%0.273CS..SBendtrans-129.3145.3-171.7-67.1177.4179.700111.3V190 R191 E198 F199 M202 E680V190-M194 HydrophobicContact CB-CE 3.99Å; V190-M194 HydrophobicContact CB-SD 4.22Å; V190-M194 HydrophobicContact CG1-CE 4.46Å; V190-M194 HydrophobicContact CG2-CE 4.14Å; V190-M194 HydrophobicContact CG2-SD 4.05Å; V190-M194 PolarHBondContact O-N 3.4Å; R191-M194 PolarHBondContact NH1-O 2.96Å; M194-E198 HydrophobicContact CB-CB 3.95Å; M194-E198 HydrophobicContact CG-CB 4.3Å; M194-F199 HydrophobicContact CB-CB 4.25Å; M194-M202 HydrophobicContact CE-CB 4.49Å; M194-M202 HydrophobicContact CE-CE 4.12Å; M194-M202 HydrophobicContact CE-CG 4.3Å; M194-M202 HydrophobicContact SD-CB 4.03Å; M194-M202 HydrophobicContact SD-CG 4.28Å; M194-E680 VanDerWaalsContact CE-OE1 3.29Å; M194-E680 WeakPolarHBondContact CE-OE1 3.28Å
195N96Very high97Very high87 Ų8752 Ų5247%0.46526%0.257SS..  trans-72.1172.2166.97252.9000111.4G197 E198 F199N195-G197 VanDerWaalsContact C-N 3.31Å; N195-G197 PolarHBondContact O-N 3.41Å; N195-G197 WeakPolarHBondContact OD1-CA 3.24Å; N195-G197 PolarHBondContact OD1-N 3.33Å; N195-E198 VanDerWaalsContact CG-CD 3.49Å; N195-E198 VanDerWaalsContact CG-OE2 3.23Å; N195-E198 PolarHBondContact N-OE2 3.15Å; N195-E198 PolarHBondContact ND2-OE1 2.98Å; N195-E198 PolarHBondContact ND2-OE2 3.31Å; N195-E198 PolarHBondContact O-N 3.28Å; N195-E198 PolarHBondContact OD1-N 3.36Å; N195-F199 VanDerWaalsContact O-CB 3.28Å; N195-F199 WeakPolarHBondContact O-CB 3.24Å; N195-F199 PolarHBondContact O-N 2.87Å
196D96.9Very high97Very high87 Ų8750.1 Ų50.147%0.46525%0.249SC..Hα-helixtrans-63.5-33.9-175.3-70.7-1.1000114R191 R200R191-D196 IonicContact CZ-OD1 2.91Å; R191-D196 VanDerWaalsContact CZ-OD1 3.31Å; R191-D196 IonicContact NH1-OD1 3.5Å; R191-D196 PolarHBondContact NH1-OD1 3.25Å; R191-D196 VanDerWaalsContact NH1-OD1 3.08Å; R191-D196 IonicContact NH2-OD1 2.75Å; R191-D196 PolarHBondContact NH2-OD1 2.76Å; D196-R200 WeakPolarHBondContact O-CB 3.42Å; D196-R200 VanDerWaalsContact O-CG 3.32Å; D196-R200 WeakPolarHBondContact O-CG 3.48Å; D196-R200 PolarHBondContact O-N 2.93Å; D196-R200 VanDerWaalsContact O-N 3.09Å; D196-R200 PolarHBondContact O-NE 2.88Å
197G97.8Very high96.9Very high35 Ų3555.5 Ų55.536%0.36127%0.273SS..Hα-helixtrans-70-49.1177.800000111.6N195 F199 R200 R201N195-G197 VanDerWaalsContact C-N 3.31Å; N195-G197 PolarHBondContact O-N 3.41Å; N195-G197 WeakPolarHBondContact OD1-CA 3.24Å; N195-G197 PolarHBondContact OD1-N 3.33Å; G197-F199 VanDerWaalsContact C-N 3.35Å; G197-F199 PolarHBondContact O-N 2.9Å; G197-R200 PolarHBondContact O-N 3.41Å; G197-R201 PolarHBondContact O-N 2.87Å; G197-R201 VanDerWaalsContact O-N 3.11Å
198E96.3Very high96.9Very high89 Ų8958.8 Ų58.842%0.41629%0.291SS..Hα-helixtrans-58.8-46.6175.5-71.4164.1169.600111.3M194 N195 R200 R201 M202M194-E198 HydrophobicContact CB-CB 3.95Å; M194-E198 HydrophobicContact CG-CB 4.3Å; N195-E198 VanDerWaalsContact CG-CD 3.49Å; N195-E198 VanDerWaalsContact CG-OE2 3.23Å; N195-E198 PolarHBondContact N-OE2 3.15Å; N195-E198 PolarHBondContact ND2-OE1 2.98Å; N195-E198 PolarHBondContact ND2-OE2 3.31Å; N195-E198 PolarHBondContact O-N 3.28Å; N195-E198 PolarHBondContact OD1-N 3.36Å; E198-R200 PolarHBondContact O-N 3.05Å; E198-R201 WeakPolarHBondContact O-CB 3.36Å; E198-R201 PolarHBondContact O-N 3.3Å; E198-M202 PolarHBondContact O-N 2.77Å
199F97.3Very high97Very high37 Ų3755.1 Ų55.116%0.16227%0.274CS..Hα-helixtrans-63.1-42.7-179.9-172.1-100.8000112.1L187 V190 R191 M194 N195 G197 R201 M202 E203L187-F199 HydrophobicContact CB-CE2 4.42Å; L187-F199 HydrophobicContact CB-CZ 4.31Å; L187-F199 HydrophobicContact CD2-CE2 4.39Å; L187-F199 VanDerWaalsContact O-CE2 3.32Å; L187-F199 WeakPolarHBondContact O-CE2 3.3Å; V190-F199 HydrophobicContact CG2-CE2 4.39Å; R191-F199 HydrophobicContact CB-CD2 4.25Å; R191-F199 HydrophobicContact CB-CE2 3.77Å; R191-F199 HydrophobicContact CB-CZ 4.26Å; R191-F199 HydrophobicContact CG-CE2 4.31Å; R191-F199 HydrophobicContact CG-CZ 4.5Å; M194-F199 HydrophobicContact CB-CB 4.25Å; N195-F199 VanDerWaalsContact O-CB 3.28Å; N195-F199 WeakPolarHBondContact O-CB 3.24Å; N195-F199 PolarHBondContact O-N 2.87Å; G197-F199 VanDerWaalsContact C-N 3.35Å; G197-F199 PolarHBondContact O-N 2.9Å; F199-R201 VanDerWaalsContact C-N 3.32Å; F199-R201 PolarHBondContact O-N 3.07Å; F199-M202 PolarHBondContact O-N 2.85Å; F199-E203 VanDerWaalsContact O-CB 3.32Å; F199-E203 WeakPolarHBondContact O-CB 3.46Å; F199-E203 PolarHBondContact O-N 3.34Å
200R98.2Very high97Very high163 Ų16356 Ų5662%0.61528%0.282SS*.Hα-helixtrans-61.2-40174.9-79.2-172.6-65.1-103.11.5112.2D196 G197 E198 E203 G204D196-R200 WeakPolarHBondContact O-CB 3.42Å; D196-R200 VanDerWaalsContact O-CG 3.32Å; D196-R200 WeakPolarHBondContact O-CG 3.48Å; D196-R200 PolarHBondContact O-N 2.93Å; D196-R200 VanDerWaalsContact O-N 3.09Å; D196-R200 PolarHBondContact O-NE 2.88Å; G197-R200 PolarHBondContact O-N 3.41Å; E198-R200 PolarHBondContact O-N 3.05Å; R200-E203 PolarHBondContact O-N 2.95Å; R200-G204 PolarHBondContact O-N 3.44Å
201R97.8Very high97.1Very high122 Ų12264 Ų6446%0.4632%0.317SS..Hα-helixtrans-64.6-47.7175.8-174.3-17563.175.23.1111.2G197 E198 F199 E203 G204 L205 E676G197-R201 PolarHBondContact O-N 2.87Å; G197-R201 VanDerWaalsContact O-N 3.11Å; E198-R201 WeakPolarHBondContact O-CB 3.36Å; E198-R201 PolarHBondContact O-N 3.3Å; F199-R201 VanDerWaalsContact C-N 3.32Å; F199-R201 PolarHBondContact O-N 3.07Å; R201-E203 VanDerWaalsContact C-N 3.31Å; R201-E203 PolarHBondContact O-N 3.25Å; R201-G204 PolarHBondContact O-N 3.3Å; R201-G204 VanDerWaalsContact O-N 3.14Å; R201-L205 PolarHBondContact O-N 3.28Å; R201-E676 IonicContact CZ-OE1 2.88Å; R201-E676 IonicContact CZ-OE2 3Å; R201-E676 IonicContact NH1-OE1 2.84Å; R201-E676 IonicContact NH1-OE2 3.69Å; R201-E676 PolarHBondContact NH1-OE2 3.35Å; R201-E676 IonicContact NH2-OE1 3.2Å; R201-E676 PolarHBondContact NH2-OE1 2.67Å; R201-E676 IonicContact NH2-OE2 3.24Å; R201-E676 PolarHBondContact NH2-OE2 2.88Å
202M97.6Very high97.1Very high0 Ų064.4 Ų64.40%033%0.325CS..Hα-helixtrans-61.7-40.7177.7-178.9527100111.5Y186 L187 M194 E198 F199 G204 L205 A206 F673 E676Y186-M202 HydrophobicContact CE1-CG 3.81Å; Y186-M202 HydrophobicContact CE1-SD 3.72Å; Y186-M202 WeakPolarHBondContact OH-CE 3.26Å; L187-M202 HydrophobicContact CD2-CG 4.01Å; M194-M202 HydrophobicContact CE-CB 4.49Å; M194-M202 HydrophobicContact CE-CE 4.12Å; M194-M202 HydrophobicContact CE-CG 4.3Å; M194-M202 HydrophobicContact SD-CB 4.03Å; M194-M202 HydrophobicContact SD-CG 4.28Å; E198-M202 PolarHBondContact O-N 2.77Å; F199-M202 PolarHBondContact O-N 2.85Å; M202-G204 VanDerWaalsContact C-N 3.3Å; M202-G204 PolarHBondContact O-N 3.31Å; M202-L205 PolarHBondContact O-N 3.34Å; M202-A206 WeakPolarHBondContact O-CB 3.06Å; M202-A206 PolarHBondContact O-N 3.27Å; M202-F673 HydrophobicContact SD-CD2 3.82Å; M202-F673 HydrophobicContact SD-CE2 3.93Å; M202-E676 HydrophobicContact CE-CB 4.12Å; M202-E676 HydrophobicContact CE-CG 3.7Å; M202-E676 WeakPolarHBondContact CE-OE1 3.29Å
203E97.9Very high97.1Very high66 Ų6665 Ų6531%0.30833%0.327SS..Hα-helixtrans-59.8-41.1174.4-162.4-164.5-158.100111.5L187 F199 R200 R201 A206 K207L187-E203 HydrophobicContact CD1-CG 4.11Å; L187-E203 HydrophobicContact CD2-CB 4.44Å; F199-E203 VanDerWaalsContact O-CB 3.32Å; F199-E203 WeakPolarHBondContact O-CB 3.46Å; F199-E203 PolarHBondContact O-N 3.34Å; R200-E203 PolarHBondContact O-N 2.95Å; R201-E203 VanDerWaalsContact C-N 3.31Å; R201-E203 PolarHBondContact O-N 3.25Å; E203-A206 PolarHBondContact O-N 3.21Å; E203-K207 VanDerWaalsContact CD-CE 3.44Å; E203-K207 HydrophobicContact CG-CD 4.13Å; E203-K207 VanDerWaalsContact O-CB 3.31Å; E203-K207 WeakPolarHBondContact O-CB 3.36Å; E203-K207 VanDerWaalsContact O-CG 3.25Å; E203-K207 WeakPolarHBondContact O-CG 3.44Å; E203-K207 PolarHBondContact O-N 3.32Å; E203-K207 VanDerWaalsContact OE1-CE 3.25Å; E203-K207 WeakPolarHBondContact OE1-CE 3.43Å; E203-K207 IonicContact OE1-NZ 3.16Å; E203-K207 PolarHBondContact OE1-NZ 3.41Å; E203-K207 IonicContact OE2-NZ 2.73Å; E203-K207 PolarHBondContact OE2-NZ 3.39Å
204G98.1Very high97.2Very high39 Ų3962.7 Ų62.740%0.40232%0.315SS..Hα-helixtrans-59.3-51.4173.200000112.7R200 R201 M202 A206 K207 D208R200-G204 PolarHBondContact O-N 3.44Å; R201-G204 PolarHBondContact O-N 3.3Å; R201-G204 VanDerWaalsContact O-N 3.14Å; M202-G204 VanDerWaalsContact C-N 3.3Å; M202-G204 PolarHBondContact O-N 3.31Å; G204-A206 VanDerWaalsContact C-N 3.33Å; G204-A206 PolarHBondContact O-N 2.84Å; G204-K207 PolarHBondContact O-N 3.34Å; G204-D208 WeakPolarHBondContact O-CB 3.48Å; G204-D208 PolarHBondContact O-N 3.01Å
205L98Very high97.3Very high39 Ų3964.8 Ų64.820%0.20433%0.33CS..Hα-helixtrans-60.4-42.2177.4-67.8-176.2000112.3R201 M202 F209 P672 F673R201-L205 PolarHBondContact O-N 3.28Å; M202-L205 PolarHBondContact O-N 3.34Å; L205-F209 VanDerWaalsContact O-CB 3.29Å; L205-F209 WeakPolarHBondContact O-CB 3.37Å; L205-F209 PolarHBondContact O-N 2.87Å; L205-P672 HydrophobicContact CD1-CB 4.43Å; L205-P672 HydrophobicContact CD2-CB 4.06Å; L205-F673 HydrophobicContact CB-CB 4.24Å; L205-F673 HydrophobicContact CB-CD2 4.4Å
206A97.8Very high97.3Very high0 Ų067.2 Ų67.20%033%0.333CS..Hα-helixtrans-67.3-41.7-179.300000112.1V183 L187 M202 E203 G204 A210 F673V183-A206 HydrophobicContact CG1-CB 3.74Å; L187-A206 HydrophobicContact CD1-CB 4.02Å; L187-A206 HydrophobicContact CD2-CB 3.93Å; L187-A206 HydrophobicContact CG-CB 4.17Å; M202-A206 WeakPolarHBondContact O-CB 3.06Å; M202-A206 PolarHBondContact O-N 3.27Å; E203-A206 PolarHBondContact O-N 3.21Å; G204-A206 VanDerWaalsContact C-N 3.33Å; G204-A206 PolarHBondContact O-N 2.84Å; A206-A210 VanDerWaalsContact O-CB 3.29Å; A206-A210 WeakPolarHBondContact O-CB 3.22Å; A206-A210 PolarHBondContact O-N 2.86Å; A206-F673 HydrophobicContact CB-CD2 3.84Å; A206-F673 HydrophobicContact CB-CE2 3.53Å; A206-F673 HydrophobicContact CB-CZ 4.26Å
207K97Very high97.3Very high114 Ų11463 Ų6350%0.49631%0.31SS..Hα-helixtrans-65.4-46.8175.2-77.4171.7179.8165.40111.4E203 G204 A210 F211E203-K207 VanDerWaalsContact CD-CE 3.44Å; E203-K207 HydrophobicContact CG-CD 4.13Å; E203-K207 VanDerWaalsContact O-CB 3.31Å; E203-K207 WeakPolarHBondContact O-CB 3.36Å; E203-K207 VanDerWaalsContact O-CG 3.25Å; E203-K207 WeakPolarHBondContact O-CG 3.44Å; E203-K207 PolarHBondContact O-N 3.32Å; E203-K207 VanDerWaalsContact OE1-CE 3.25Å; E203-K207 WeakPolarHBondContact OE1-CE 3.43Å; E203-K207 IonicContact OE1-NZ 3.16Å; E203-K207 PolarHBondContact OE1-NZ 3.41Å; E203-K207 IonicContact OE2-NZ 2.73Å; E203-K207 PolarHBondContact OE2-NZ 3.39Å; G204-K207 PolarHBondContact O-N 3.34Å; K207-A210 PolarHBondContact O-N 3.02Å; K207-F211 WeakPolarHBondContact O-CB 3.39Å; K207-F211 PolarHBondContact O-N 3.25Å
208D97.7Very high97.3Very high88 Ų8862 Ų6247%0.47130%0.296SS..Hα-helixtrans-57.8-49.1175.5176.868.4000111.2G204 A210 F211 N212G204-D208 WeakPolarHBondContact O-CB 3.48Å; G204-D208 PolarHBondContact O-N 3.01Å; D208-A210 PolarHBondContact O-N 3.06Å; D208-F211 PolarHBondContact O-N 2.95Å; D208-N212 WeakPolarHBondContact O-CB 3.43Å; D208-N212 PolarHBondContact O-N 2.91Å; D208-N212 PolarHBondContact OD1-ND2 3.17Å
209F98.3Very high97.3Very high3 Ų364.6 Ų64.61%0.01330%0.302CS..Hα-helixtrans-58-47.7176.1175-104.3000112.2V179 V183 L205 F211 L213 G214 L217 L660 S671 F673 L674V179-F209 HydrophobicContact CG1-CD1 4.26Å; V179-F209 HydrophobicContact CG1-CE1 3.92Å; V183-F209 HydrophobicContact CG2-CD1 4.2Å; L205-F209 VanDerWaalsContact O-CB 3.29Å; L205-F209 WeakPolarHBondContact O-CB 3.37Å; L205-F209 PolarHBondContact O-N 2.87Å; F209-F211 VanDerWaalsContact C-N 3.27Å; F209-F211 PolarHBondContact O-N 3.01Å; F209-L213 HydrophobicContact CD2-CB 4.14Å; F209-L213 HydrophobicContact CD2-CD2 4.42Å; F209-L213 HydrophobicContact CD2-CG 4.46Å; F209-L213 HydrophobicContact CE2-CB 4.36Å; F209-L213 HydrophobicContact CE2-CD2 4.33Å; F209-L213 HydrophobicContact CE2-CG 4.27Å; F209-L213 PolarHBondContact O-N 3.4Å; F209-G214 WeakPolarHBondContact O-CA 3.35Å; F209-G214 PolarHBondContact O-N 3.32Å; F209-L217 HydrophobicContact CE2-CD1 3.78Å; F209-L217 HydrophobicContact CZ-CD1 4.11Å; F209-L660 HydrophobicContact CE1-CD1 4.28Å; F209-L660 HydrophobicContact CZ-CD1 4.13Å; F209-S671 WeakPolarHBondContact CD2-OG 3.38Å; F209-F673 HydrophobicContact CB-CB 3.84Å; F209-F673 HydrophobicContact CB-CD1 3.81Å; F209-F673 HydrophobicContact CB-CG 3.93Å; F209-F673 AromaticContact CD1-CD1 3.36Å; F209-F673 HydrophobicContact CD1-CD1 3.36Å; F209-F673 AromaticContact CD1-CE1 3.6Å; F209-F673 HydrophobicContact CD1-CE1 3.6Å; F209-F673 HydrophobicContact CD1-CG 4.32Å; F209-F673 HydrophobicContact CD2-CD1 4.13Å; F209-F673 AromaticContact CE1-CD1 3.92Å; F209-F673 HydrophobicContact CE1-CD1 3.92Å; F209-F673 AromaticContact CE1-CE1 3.96Å; F209-F673 HydrophobicContact CE1-CE1 3.96Å; F209-F673 HydrophobicContact CG-CB 4.21Å; F209-F673 AromaticContact CG-CD1 3.48Å; F209-F673 HydrophobicContact CG-CD1 3.48Å; F209-F673 VanDerWaalsContact CG-CD1 3.48Å; F209-F673 HydrophobicContact CG-CE1 4.2Å; F209-F673 HydrophobicContact CG-CG 4.1Å; F209-L674 HydrophobicContact CD2-CG 4.38Å; F209-L674 HydrophobicContact CE1-CD2 4.27Å; F209-L674 HydrophobicContact CE2-CD1 3.63Å; F209-L674 HydrophobicContact CE2-CD2 4.2Å; F209-L674 HydrophobicContact CE2-CG 3.77Å; F209-L674 HydrophobicContact CZ-CD1 3.87Å; F209-L674 HydrophobicContact CZ-CD2 3.82Å; F209-L674 HydrophobicContact CZ-CG 3.92Å
210A97.3Very high97.1Very high30 Ų3067 Ų6725%0.24831%0.311CS..Hα-helixtrans-64.8-29.8-177.500000113.3V179 V183 A206 K207 D208 P215V179-A210 HydrophobicContact CG1-CB 4.22Å; V183-A210 HydrophobicContact CG2-CB 4.3Å; A206-A210 VanDerWaalsContact O-CB 3.29Å; A206-A210 WeakPolarHBondContact O-CB 3.22Å; A206-A210 PolarHBondContact O-N 2.86Å; K207-A210 PolarHBondContact O-N 3.02Å; D208-A210 PolarHBondContact O-N 3.06Å; A210-P215 WeakPolarHBondContact O-CD 3.32Å
211F96.7Very high96.8Very high168 Ų16859.2 Ų59.274%0.73728%0.281SS*.Hα-helixtrans-87-42.7179.6-172-98.5000112.6K207 D208 F209K207-F211 WeakPolarHBondContact O-CB 3.39Å; K207-F211 PolarHBondContact O-N 3.25Å; D208-F211 PolarHBondContact O-N 2.95Å; F209-F211 VanDerWaalsContact C-N 3.27Å; F209-F211 PolarHBondContact O-N 3.01Å
212N95.8Very high96.6Very high91 Ų9158.2 Ų58.249%0.48728%0.28SS..THydrogen-bonded Turntrans-95.2-82.9-172.2-69.1-48.4000112.4D208 P215D208-N212 WeakPolarHBondContact O-CB 3.43Å; D208-N212 PolarHBondContact O-N 2.91Å; D208-N212 PolarHBondContact OD1-ND2 3.17Å; N212-P215 WeakPolarHBondContact O-CD 3.49Å
213L96.5Very high96.3Very high34 Ų3461 Ų6118%0.17830%0.295CS..Hα-helixtrans-74.9-36.7-168.6-179.659.8000113.5F209 R216 L217 V669F209-L213 HydrophobicContact CD2-CB 4.14Å; F209-L213 HydrophobicContact CD2-CD2 4.42Å; F209-L213 HydrophobicContact CD2-CG 4.46Å; F209-L213 HydrophobicContact CE2-CB 4.36Å; F209-L213 HydrophobicContact CE2-CD2 4.33Å; F209-L213 HydrophobicContact CE2-CG 4.27Å; F209-L213 PolarHBondContact O-N 3.4Å; L213-R216 WeakPolarHBondContact O-CB 3.45Å; L213-R216 PolarHBondContact O-N 3.05Å; L213-R216 VanDerWaalsContact O-N 3.13Å; L213-L217 HydrophobicContact CD1-CD1 4.4Å; L213-L217 HydrophobicContact CD1-CD2 4.16Å; L213-L217 HydrophobicContact CD1-CG 4.07Å; L213-L217 HydrophobicContact CD2-CD1 4.16Å; L213-L217 HydrophobicContact CG-CD1 3.85Å; L213-L217 HydrophobicContact CG-CD2 4.49Å; L213-L217 HydrophobicContact CG-CG 3.98Å; L213-L217 PolarHBondContact O-N 2.74Å; L213-L217 VanDerWaalsContact O-N 3.15Å; L213-V669 HydrophobicContact CD1-CG2 3.97Å; L213-V669 HydrophobicContact CD2-CG2 4.32Å
214G97.1Very high95.9Very high0 Ų059.4 Ų59.40%029%0.287CS..Hα-helixtrans-53.1-49.9-175.300000114.2F209 R216 L217 Q218F209-G214 WeakPolarHBondContact O-CA 3.35Å; F209-G214 PolarHBondContact O-N 3.32Å; G214-R216 VanDerWaalsContact C-N 3.29Å; G214-R216 PolarHBondContact O-N 3.28Å; G214-L217 PolarHBondContact O-N 2.93Å; G214-Q218 VanDerWaalsContact O-CB 3.29Å; G214-Q218 WeakPolarHBondContact O-CB 3.47Å; G214-Q218 PolarHBondContact O-N 3.25Å
215P97.2Very high95.5Very high68 Ų6858.6 Ų58.644%0.44228%0.275SS..Hα-helixtrans-56.5-38.2176.8-28.635.8000114.1A210 N212 W219A210-P215 WeakPolarHBondContact O-CD 3.32Å; N212-P215 WeakPolarHBondContact O-CD 3.49Å; P215-W219 PolarHBondContact O-N 2.91Å; P215-W219 VanDerWaalsContact O-N 3.12Å
216R96.7Very high95Very high138 Ų13864.5 Ų64.552%0.52130%0.295SS..Hα-helixtrans-66.5-48.2176.8-176.6178.3177.3-177.3-2.5111L213 G214 Q218 W219 Y220L213-R216 WeakPolarHBondContact O-CB 3.45Å; L213-R216 PolarHBondContact O-N 3.05Å; L213-R216 VanDerWaalsContact O-N 3.13Å; G214-R216 VanDerWaalsContact C-N 3.29Å; G214-R216 PolarHBondContact O-N 3.28Å; R216-Q218 VanDerWaalsContact C-N 3.34Å; R216-Q218 PolarHBondContact O-N 3.11Å; R216-W219 WeakPolarHBondContact O-CB 3.43Å; R216-W219 PolarHBondContact O-N 2.77Å; R216-Y220 HydrophobicContact CG-CE2 4.2Å; R216-Y220 VanDerWaalsContact O-CD2 3.29Å; R216-Y220 WeakPolarHBondContact O-CD2 3.34Å
217L96.3Very high94.4Very high0 Ų074.8 Ų74.80%033%0.334CS..Hα-helixtrans-63.1-41.5177.7-58.4-178.3000111.6F209 L213 G214 W219 Y220 L221 L660 V663 L667 V669 L674F209-L217 HydrophobicContact CE2-CD1 3.78Å; F209-L217 HydrophobicContact CZ-CD1 4.11Å; L213-L217 HydrophobicContact CD1-CD1 4.4Å; L213-L217 HydrophobicContact CD1-CD2 4.16Å; L213-L217 HydrophobicContact CD1-CG 4.07Å; L213-L217 HydrophobicContact CD2-CD1 4.16Å; L213-L217 HydrophobicContact CG-CD1 3.85Å; L213-L217 HydrophobicContact CG-CD2 4.49Å; L213-L217 HydrophobicContact CG-CG 3.98Å; L213-L217 PolarHBondContact O-N 2.74Å; L213-L217 VanDerWaalsContact O-N 3.15Å; G214-L217 PolarHBondContact O-N 2.93Å; L217-W219 VanDerWaalsContact C-N 3.26Å; L217-W219 PolarHBondContact O-N 2.85Å; L217-Y220 PolarHBondContact O-N 3.46Å; L217-L221 PolarHBondContact O-N 2.73Å; L217-L660 HydrophobicContact CB-CD2 3.65Å; L217-L660 HydrophobicContact CD1-CB 4.38Å; L217-V663 HydrophobicContact CB-CG1 4.31Å; L217-V663 HydrophobicContact CD2-CB 4.3Å; L217-V663 HydrophobicContact CD2-CG1 3.72Å; L217-L667 HydrophobicContact CD2-CD1 3.76Å; L217-V669 HydrophobicContact CD2-CG2 4.31Å; L217-L674 HydrophobicContact CD1-CD1 3.79Å
218Q97.4Very high94Very high12 Ų1270.2 Ų70.26%0.05632%0.317CS..Hα-helixtrans-57.4-38.5175.9-177.275.428.900112.2P177 V179 G214 R216 L221 K222 H656P177-Q218 PolarHBondContact O-NE2 3.03Å; P177-Q218 PolarHBondContact O-OE1 3.1Å; V179-Q218 HydrophobicContact CG2-CB 3.79Å; V179-Q218 HydrophobicContact CG2-CG 4.11Å; G214-Q218 VanDerWaalsContact O-CB 3.29Å; G214-Q218 WeakPolarHBondContact O-CB 3.47Å; G214-Q218 PolarHBondContact O-N 3.25Å; R216-Q218 VanDerWaalsContact C-N 3.34Å; R216-Q218 PolarHBondContact O-N 3.11Å; Q218-L221 PolarHBondContact O-N 2.99Å; Q218-K222 HydrophobicContact CG-CD 4.3Å; Q218-K222 HydrophobicContact CG-CG 4.47Å; Q218-K222 WeakPolarHBondContact O-CB 3.29Å; Q218-K222 WeakPolarHBondContact O-CG 3.38Å; Q218-K222 PolarHBondContact O-N 2.93Å; Q218-H656 PolarHBondContact OE1-CE1 3.23Å; Q218-H656 PolarHBondContact OE1-NE2 3.18Å
219W96Very high93.5Very high145 Ų14568.4 Ų68.455%0.54931%0.31SS..Hα-helixtrans-62.1-46.9179.7-178.290.1000111.7P215 R216 L217 L221 K222 L223P215-W219 PolarHBondContact O-N 2.91Å; P215-W219 VanDerWaalsContact O-N 3.12Å; R216-W219 WeakPolarHBondContact O-CB 3.43Å; R216-W219 PolarHBondContact O-N 2.77Å; L217-W219 VanDerWaalsContact C-N 3.26Å; L217-W219 PolarHBondContact O-N 2.85Å; W219-L221 VanDerWaalsContact C-N 3.31Å; W219-L221 PolarHBondContact O-N 3.01Å; W219-K222 PolarHBondContact O-N 3.01Å; W219-L223 HydrophobicContact CH2-CD2 4.21Å; W219-L223 HydrophobicContact CZ3-CD2 4.23Å; W219-L223 PolarHBondContact O-N 2.64Å
220Y93.3Very high93.4Very high86 Ų8668.5 Ų68.534%0.33731%0.31SS..Hα-helixtrans-64.2-37.2174.8-71.6-79.1000112.1R216 L217 L223 K224 V663 L667R216-Y220 HydrophobicContact CG-CE2 4.2Å; R216-Y220 VanDerWaalsContact O-CD2 3.29Å; R216-Y220 WeakPolarHBondContact O-CD2 3.34Å; L217-Y220 PolarHBondContact O-N 3.46Å; Y220-L223 WeakPolarHBondContact O-CB 3.34Å; Y220-L223 PolarHBondContact O-N 2.92Å; Y220-K224 PolarHBondContact O-N 3.22Å; Y220-V663 HydrophobicContact CD2-CG1 4.24Å; Y220-V663 HydrophobicContact CG-CG1 4.25Å; Y220-L667 HydrophobicContact CD2-CD1 3.84Å; Y220-L667 HydrophobicContact CE1-CD2 4.47Å; Y220-L667 HydrophobicContact CE2-CD1 3.66Å; Y220-L667 HydrophobicContact CE2-CD2 4.03Å; Y220-L667 HydrophobicContact CE2-CG 4.45Å
221L91.9Very high93.2Very high0 Ų067.3 Ų67.30%030%0.299CS..Hα-helixtrans-66.5-40.2177.8-167.458.2000112.3V176 L217 Q218 W219 K224 S225 Y231 W235 H656 C659 L660V176-L221 HydrophobicContact CG1-CB 4.49Å; V176-L221 HydrophobicContact CG1-CD2 3.72Å; V176-L221 HydrophobicContact CG1-CG 3.89Å; L217-L221 PolarHBondContact O-N 2.73Å; Q218-L221 PolarHBondContact O-N 2.99Å; W219-L221 VanDerWaalsContact C-N 3.31Å; W219-L221 PolarHBondContact O-N 3.01Å; L221-K224 PolarHBondContact O-N 3.5Å; L221-S225 PolarHBondContact O-N 3.42Å; L221-Y231 HydrophobicContact CD1-CD2 3.53Å; L221-Y231 HydrophobicContact CD1-CE2 4.11Å; L221-Y231 HydrophobicContact CD1-CG 4.4Å; L221-Y231 HydrophobicContact CD2-CD2 4.27Å; L221-Y231 HydrophobicContact CD2-CE2 4.01Å; L221-Y231 HydrophobicContact CG-CD2 3.98Å; L221-Y231 HydrophobicContact CG-CE2 4.21Å; L221-W235 HydrophobicContact CD1-CZ3 4.01Å; L221-H656 VanDerWaalsContact CD2-CD2 3.48Å; L221-H656 WeakPolarHBondContact CD2-CD2 3.48Å; L221-C659 HydrophobicContact CD1-CB 3.7Å; L221-C659 HydrophobicContact CD2-CB 3.94Å; L221-L660 HydrophobicContact CD2-CD2 4.06Å; L221-L660 HydrophobicContact CD2-CG 4.3Å
222K94.7Very high93.1Very high101 Ų10159.7 Ų59.744%0.43927%0.267SS..Hα-helixtrans-61.4-43.7171.2-75.5176.4177.4-179.80111.1Q218 W219 K224 S225 W226Q218-K222 HydrophobicContact CG-CD 4.3Å; Q218-K222 HydrophobicContact CG-CG 4.47Å; Q218-K222 WeakPolarHBondContact O-CB 3.29Å; Q218-K222 WeakPolarHBondContact O-CG 3.38Å; Q218-K222 PolarHBondContact O-N 2.93Å; W219-K222 PolarHBondContact O-N 3.01Å; K222-K224 PolarHBondContact O-N 3.35Å; K222-S225 WeakPolarHBondContact O-CB 3.34Å; K222-S225 PolarHBondContact O-N 2.87Å; K222-S225 VanDerWaalsContact O-N 3.11Å; K222-S225 PolarHBondContact O-OG 3.12Å; K222-W226 PolarHBondContact O-N 2.98Å
223L90.4Very high92.9Very high58 Ų5856.2 Ų56.230%0.30425%0.25SC..Hα-helixtrans-57.4-48.4174.5-176.463.6000110.8W219 Y220 S225 W226 W227W219-L223 HydrophobicContact CH2-CD2 4.21Å; W219-L223 HydrophobicContact CZ3-CD2 4.23Å; W219-L223 PolarHBondContact O-N 2.64Å; Y220-L223 WeakPolarHBondContact O-CB 3.34Å; Y220-L223 PolarHBondContact O-N 2.92Å; L223-S225 VanDerWaalsContact C-N 3.28Å; L223-S225 PolarHBondContact O-N 3.24Å; L223-W226 HydrophobicContact CD1-CE3 3.78Å; L223-W226 HydrophobicContact CD1-CZ3 4.08Å; L223-W226 WeakPolarHBondContact O-CB 3.35Å; L223-W226 PolarHBondContact O-N 2.98Å; L223-W227 VanDerWaalsContact O-CD1 3.27Å
224K90.4Very high92.6Very high33 Ų3358.3 Ų58.314%0.14326%0.261CS..Hα-helixtrans-56-41.6174.5177.1171.3165.268.90112.1Y220 L221 K222 W226 W227 A228 Y231 D234 W235Y220-K224 PolarHBondContact O-N 3.22Å; L221-K224 PolarHBondContact O-N 3.5Å; K222-K224 PolarHBondContact O-N 3.35Å; K224-W226 PolarHBondContact O-N 2.92Å; K224-W227 PolarHBondContact O-N 3.07Å; K224-W227 VanDerWaalsContact O-N 3.17Å; K224-A228 HydrophobicContact CG-CB 4.19Å; K224-A228 VanDerWaalsContact O-CB 3.28Å; K224-A228 WeakPolarHBondContact O-CB 3.42Å; K224-A228 PolarHBondContact O-N 3.02Å; K224-Y231 WeakPolarHBondContact CE-O 3.24Å; K224-D234 IonicContact NZ-OD1 3.7Å; K224-D234 PolarHBondContact NZ-OD1 3.1Å; K224-D234 IonicContact NZ-OD2 3.99Å; K224-D234 PolarHBondContact NZ-OD2 2.94Å; K224-W235 HydrophobicContact CD-CD2 4.17Å; K224-W235 HydrophobicContact CD-CE3 4.04Å; K224-W235 HydrophobicContact CD-CH2 3.38Å; K224-W235 HydrophobicContact CD-CZ2 3.5Å; K224-W235 HydrophobicContact CD-CZ3 3.67Å
225S89.6Confident92.4Very high22 Ų2259.6 Ų59.615%0.15427%0.266CS..Hα-helixtrans-64-21.817981.70000114.6R173 L221 K222 L223R173-S225 PolarHBondContact NH1-O 3.33Å; L221-S225 PolarHBondContact O-N 3.42Å; K222-S225 WeakPolarHBondContact O-CB 3.34Å; K222-S225 PolarHBondContact O-N 2.87Å; K222-S225 VanDerWaalsContact O-N 3.11Å; K222-S225 PolarHBondContact O-OG 3.12Å; L223-S225 VanDerWaalsContact C-N 3.28Å; L223-S225 PolarHBondContact O-N 3.24Å
226W86.4Confident92.1Very high164 Ų16457.7 Ų57.762%0.62125%0.25SC*.Hα-helixtrans-77.1-34.5175.6-62-16000112.3R173 K222 L223 K224R173-W226 PolarHBondContact NH1-O 3.34Å; K222-W226 PolarHBondContact O-N 2.98Å; L223-W226 HydrophobicContact CD1-CE3 3.78Å; L223-W226 HydrophobicContact CD1-CZ3 4.08Å; L223-W226 WeakPolarHBondContact O-CB 3.35Å; L223-W226 PolarHBondContact O-N 2.98Å; K224-W226 PolarHBondContact O-N 2.92Å
227W86.2Confident91.9Very high215 Ų21553 Ų5381%0.81423%0.234SC*.Hα-helixtrans-95.5-35.6-176.4-66.397.6000113.5L223 K224L223-W227 VanDerWaalsContact O-CD1 3.27Å; K224-W227 PolarHBondContact O-N 3.07Å; K224-W227 VanDerWaalsContact O-N 3.17Å
228A87.4Confident91.6Very high18 Ų1855.4 Ų55.415%0.14925%0.245CC..SBendtrans-80.7150.1179.600000112.2K224 N230K224-A228 HydrophobicContact CG-CB 4.19Å; K224-A228 VanDerWaalsContact O-CB 3.28Å; K224-A228 WeakPolarHBondContact O-CB 3.42Å; K224-A228 PolarHBondContact O-N 3.02Å; A228-N230 VanDerWaalsContact C-N 3.32Å; A228-N230 WeakPolarHBondContact CB-O 2.98Å
229T88.9Confident91.2Very high51 Ų5157.6 Ų57.631%0.31325%0.253SS..SBendtrans-64.9-38.7167.839.30000111.4R173 E599R173-T229 WeakPolarHBondContact CG-O 3.41Å; T229-E599 WeakPolarHBondContact CB-OE1 3.45Å; T229-E599 VanDerWaalsContact CB-OE2 3.3Å; T229-E599 WeakPolarHBondContact CB-OE2 3.25Å; T229-E599 VanDerWaalsContact OG1-CD 3.31Å; T229-E599 PolarHBondContact OG1-OE1 3.23Å; T229-E599 PolarHBondContact OG1-OE2 2.84Å
230N94.9Very high90.8Very high5 Ų554 Ų543%0.02724%0.244CC..  trans-144.3133.3171-169.6-46.8000108.5A228 V232 S233 R598 E599A228-N230 VanDerWaalsContact C-N 3.32Å; A228-N230 WeakPolarHBondContact CB-O 2.98Å; N230-V232 VanDerWaalsContact C-N 3.28Å; N230-V232 PolarHBondContact O-N 2.75Å; N230-V232 PolarHBondContact OD1-N 2.76Å; N230-S233 WeakPolarHBondContact CB-OG 3.33Å; N230-S233 PolarHBondContact ND2-OG 2.81Å; N230-S233 PolarHBondContact OD1-OG 3.43Å; N230-R598 PolarHBondContact ND2-O 3.26Å; N230-E599 HydrophobicContact CB-CB 4.07Å
231Y94.2Very high90.8Very high4 Ų450.9 Ų50.92%0.01623%0.232CC..THydrogen-bonded Turntrans-81.1-6.8-175.777.2-89.1000113.7L174 P175 V176 P177 L221 K224 C659L174-Y231 HydrophobicContact CB-CD1 4.32Å; L174-Y231 HydrophobicContact CB-CE1 4.06Å; L174-Y231 HydrophobicContact CD2-CD1 4.38Å; L174-Y231 HydrophobicContact CD2-CE1 3.73Å; L174-Y231 HydrophobicContact CG-CE1 3.79Å; L174-Y231 WeakPolarHBondContact O-CD1 3.36Å; L174-Y231 WeakPolarHBondContact O-CE1 3.39Å; P175-Y231 VanDerWaalsContact O-CE1 3.24Å; P175-Y231 WeakPolarHBondContact O-CE1 3.38Å; P175-Y231 PolarHBondContact O-OH 3.25Å; V176-Y231 HydrophobicContact CB-CE1 4.48Å; V176-Y231 HydrophobicContact CG2-CD1 3.86Å; V176-Y231 HydrophobicContact CG2-CE1 3.87Å; V176-Y231 HydrophobicContact CG2-CG 4.21Å; P177-Y231 WeakPolarHBondContact CD-OH 3.33Å; L221-Y231 HydrophobicContact CD1-CD2 3.53Å; L221-Y231 HydrophobicContact CD1-CE2 4.11Å; L221-Y231 HydrophobicContact CD1-CG 4.4Å; L221-Y231 HydrophobicContact CD2-CD2 4.27Å; L221-Y231 HydrophobicContact CD2-CE2 4.01Å; L221-Y231 HydrophobicContact CG-CD2 3.98Å; L221-Y231 HydrophobicContact CG-CE2 4.21Å; K224-Y231 WeakPolarHBondContact CE-O 3.24Å; Y231-C659 HydrophobicContact CD2-CB 4.43Å; Y231-C659 HydrophobicContact CE2-CB 4.31Å
232V94.8Very high90.9Very high8 Ų851.5 Ų51.55%0.04824%0.235CC..THydrogen-bonded Turntrans-106.1-42.8-177.8178.10000111.5L174 N230 D234 W235 W236 R655L174-V232 HydrophobicContact CD2-CB 4.12Å; L174-V232 HydrophobicContact CD2-CG2 3.55Å; N230-V232 VanDerWaalsContact C-N 3.28Å; N230-V232 PolarHBondContact O-N 2.75Å; N230-V232 PolarHBondContact OD1-N 2.76Å; V232-D234 PolarHBondContact O-N 3.25Å; V232-W235 PolarHBondContact O-N 3.3Å; V232-W236 HydrophobicContact CG1-CB 4.04Å; V232-W236 WeakPolarHBondContact O-CB 3.49Å; V232-W236 PolarHBondContact O-N 2.94Å; V232-R655 HydrophobicContact CG1-CB 4.04Å; V232-R655 HydrophobicContact CG1-CG 4.16Å; V232-R655 HydrophobicContact CG2-CB 4.25Å
233S90.8Very high90.9Very high19 Ų1951.5 Ų51.513%0.13323%0.232CC..Hα-helixtrans-61.8-41.4-158.9-520000115.2N230 W236 E237 E599N230-S233 WeakPolarHBondContact CB-OG 3.33Å; N230-S233 PolarHBondContact ND2-OG 2.81Å; N230-S233 PolarHBondContact OD1-OG 3.43Å; S233-W236 PolarHBondContact O-N 3.23Å; S233-E237 WeakPolarHBondContact O-CB 3.44Å; S233-E237 PolarHBondContact O-N 3.24Å; S233-E599 PolarHBondContact OG-O 3.02Å
234D89.6Confident90.9Very high77 Ų7750.2 Ų50.241%0.41223%0.233SC..Hα-helixtrans-67.1-46.8178.859.2-22.9000111.6K224 V232 E237 E238K224-D234 IonicContact NZ-OD1 3.7Å; K224-D234 PolarHBondContact NZ-OD1 3.1Å; K224-D234 IonicContact NZ-OD2 3.99Å; K224-D234 PolarHBondContact NZ-OD2 2.94Å; V232-D234 PolarHBondContact O-N 3.25Å; D234-E237 PolarHBondContact O-N 3.39Å; D234-E238 WeakPolarHBondContact O-CB 3.38Å; D234-E238 PolarHBondContact O-N 2.99Å
235W92.9Very high91.1Very high28 Ų2851.6 Ų51.611%0.10624%0.238CC..Hα-helixtrans-66.7-36.1175.5-72-11.2000112.6L221 K224 V232 Y239 F658 C659 V662 V663 Y666L221-W235 HydrophobicContact CD1-CZ3 4.01Å; K224-W235 HydrophobicContact CD-CD2 4.17Å; K224-W235 HydrophobicContact CD-CE3 4.04Å; K224-W235 HydrophobicContact CD-CH2 3.38Å; K224-W235 HydrophobicContact CD-CZ2 3.5Å; K224-W235 HydrophobicContact CD-CZ3 3.67Å; V232-W235 PolarHBondContact O-N 3.3Å; W235-Y239 HydrophobicContact CB-CD2 3.91Å; W235-Y239 HydrophobicContact CB-CE2 4.18Å; W235-Y239 AromaticContact CD1-CE2 3.77Å; W235-Y239 HydrophobicContact CG-CD2 4.23Å; W235-Y239 AromaticContact CG-CE2 3.99Å; W235-Y239 HydrophobicContact CG-CE2 3.99Å; W235-Y239 WeakPolarHBondContact O-CB 3.28Å; W235-Y239 VanDerWaalsContact O-CD2 3.26Å; W235-Y239 WeakPolarHBondContact O-CD2 3.43Å; W235-Y239 PolarHBondContact O-N 2.91Å; W235-F658 HydrophobicContact CB-CE1 4.04Å; W235-F658 HydrophobicContact CB-CZ 4.3Å; W235-C659 HydrophobicContact CE3-CB 4.14Å; W235-C659 HydrophobicContact CZ3-CB 4.14Å; W235-V662 HydrophobicContact CD2-CB 4.4Å; W235-V662 HydrophobicContact CD2-CG1 3.68Å; W235-V662 HydrophobicContact CE3-CB 4.02Å; W235-V662 HydrophobicContact CE3-CG1 3.75Å; W235-V662 HydrophobicContact CG-CG1 4.23Å; W235-V662 HydrophobicContact CH2-CG1 4.09Å; W235-V662 HydrophobicContact CZ2-CG1 4.04Å; W235-V662 HydrophobicContact CZ3-CB 4.18Å; W235-V662 HydrophobicContact CZ3-CG1 3.95Å; W235-V663 HydrophobicContact CH2-CG2 3.71Å; W235-V663 HydrophobicContact CZ3-CG2 3.93Å; W235-Y666 HydrophobicContact CZ2-CD2 4.33Å; W235-Y666 AromaticContact CZ2-CE2 3.84Å; W235-Y666 HydrophobicContact CZ2-CE2 3.84Å
236W92.3Very high91.4Very high27 Ų2752.2 Ų52.210%0.10225%0.248CC..Hα-helixtrans-65.8-46176.2-173.1-102.7000111.4V232 S233 I240 Y241 R655 F658V232-W236 HydrophobicContact CG1-CB 4.04Å; V232-W236 WeakPolarHBondContact O-CB 3.49Å; V232-W236 PolarHBondContact O-N 2.94Å; S233-W236 PolarHBondContact O-N 3.23Å; W236-I240 HydrophobicContact CD2-CB 4.33Å; W236-I240 HydrophobicContact CD2-CG1 3.64Å; W236-I240 HydrophobicContact CE3-CB 4.45Å; W236-I240 HydrophobicContact CE3-CD1 4.03Å; W236-I240 HydrophobicContact CE3-CG1 3.33Å; W236-I240 HydrophobicContact CG-CG1 4.4Å; W236-I240 HydrophobicContact CH2-CB 4.44Å; W236-I240 HydrophobicContact CH2-CD1 4.01Å; W236-I240 HydrophobicContact CH2-CG1 3.68Å; W236-I240 HydrophobicContact CH2-CG2 4.1Å; W236-I240 HydrophobicContact CZ2-CB 4.33Å; W236-I240 HydrophobicContact CZ2-CG1 3.98Å; W236-I240 HydrophobicContact CZ2-CG2 3.9Å; W236-I240 HydrophobicContact CZ3-CD1 3.63Å; W236-I240 HydrophobicContact CZ3-CG1 3.37Å; W236-I240 VanDerWaalsContact O-CB 3.29Å; W236-I240 WeakPolarHBondContact O-CB 3.44Å; W236-I240 PolarHBondContact O-N 3.42Å; W236-Y241 AromaticContact CD1-CE2 3.72Å; W236-Y241 AromaticContact NE1-CE2 3.48Å; W236-Y241 AromaticContact NE1-CZ 3.84Å; W236-Y241 PolarHBondContact NE1-OH 3.12Å; W236-R655 VanDerWaalsContact CE3-CD 3.44Å; W236-R655 VanDerWaalsContact CH2-CZ 3.4Å; W236-F658 HydrophobicContact CE3-CD1 4.09Å; W236-F658 HydrophobicContact CE3-CE1 4.09Å; W236-F658 HydrophobicContact CE3-CG 4.46Å; W236-F658 HydrophobicContact CE3-CZ 4.46Å; W236-F658 HydrophobicContact CZ3-CG 4.48Å
237E92.4Very high91.9Very high40 Ų4045.2 Ų45.219%0.18722%0.223CC..Iπ-helixtrans-58-49.5174.6-176.7170.699.100111.1S233 D234 Y241 L242 R310 L325S233-E237 WeakPolarHBondContact O-CB 3.44Å; S233-E237 PolarHBondContact O-N 3.24Å; D234-E237 PolarHBondContact O-N 3.39Å; E237-Y241 PolarHBondContact O-N 2.98Å; E237-L242 HydrophobicContact CG-CD1 4.02Å; E237-L242 HydrophobicContact CG-CG 4.44Å; E237-L242 WeakPolarHBondContact O-CG 3.23Å; E237-L242 PolarHBondContact O-N 2.97Å; E237-L242 VanDerWaalsContact O-N 3.16Å; E237-R310 IonicContact OE1-CZ 3.92Å; E237-R310 IonicContact OE1-NH1 2.87Å; E237-R310 PolarHBondContact OE1-NH1 2.98Å; E237-R310 IonicContact OE2-CZ 2.76Å; E237-R310 IonicContact OE2-NH1 3.86Å; E237-R310 PolarHBondContact OE2-NH1 3.47Å; E237-L325 HydrophobicContact CG-CD1 4.38Å
238E88.7Confident92.4Very high51 Ų5135.3 Ų35.324%0.23819%0.186CC..Iπ-helixtrans-68.3-57.9-175.7-173.5-179.5176.100113.2D234 L242 R243 T322D234-E238 WeakPolarHBondContact O-CB 3.38Å; D234-E238 PolarHBondContact O-N 2.99Å; E238-L242 CarbonylContact O-C 3.57Å; E238-L242 WeakPolarHBondContact O-CA 3.38Å; E238-L242 WeakPolarHBondContact O-CB 3.2Å; E238-L242 PolarHBondContact O-N 3.17Å; E238-L242 VanDerWaalsContact O-N 3.13Å; E238-R243 HydrophobicContact CG-CG 4.28Å; E238-R243 WeakPolarHBondContact O-CG 3.28Å; E238-R243 PolarHBondContact O-N 3.48Å; E238-R243 IonicContact OE1-CZ 3.67Å; E238-R243 VanDerWaalsContact OE1-CZ 3.24Å; E238-R243 IonicContact OE1-NE 3.62Å; E238-R243 PolarHBondContact OE1-NE 3.19Å; E238-R243 IonicContact OE1-NH2 3.82Å; E238-R243 PolarHBondContact OE1-NH2 3.02Å; E238-T322 HydrophobicContact CG-CG2 4.3Å
239Y88.9Confident92.8Very high58 Ų5834.4 Ų34.423%0.22718%0.179CC..Iπ-helixtrans-81.6-29.5-167.3-69-73.7000113.8W235 R243 F658 V662 Y666W235-Y239 HydrophobicContact CB-CD2 3.91Å; W235-Y239 HydrophobicContact CB-CE2 4.18Å; W235-Y239 AromaticContact CD1-CE2 3.77Å; W235-Y239 HydrophobicContact CG-CD2 4.23Å; W235-Y239 AromaticContact CG-CE2 3.99Å; W235-Y239 HydrophobicContact CG-CE2 3.99Å; W235-Y239 WeakPolarHBondContact O-CB 3.28Å; W235-Y239 VanDerWaalsContact O-CD2 3.26Å; W235-Y239 WeakPolarHBondContact O-CD2 3.43Å; W235-Y239 PolarHBondContact O-N 2.91Å; Y239-R243 VanDerWaalsContact CD1-CD 3.47Å; Y239-R243 VanDerWaalsContact CE1-CZ 3.45Å; Y239-F658 HydrophobicContact CD2-CZ 4.21Å; Y239-F658 HydrophobicContact CG-CZ 4.4Å; Y239-V662 HydrophobicContact CD2-CG1 4.34Å; Y239-V662 HydrophobicContact CD2-CG2 4.02Å; Y239-V662 HydrophobicContact CE2-CG1 3.75Å; Y239-V662 HydrophobicContact CE2-CG2 4.25Å; Y239-Y666 PolarHBondContact OH-OH 3.17Å
240I88.9Confident93.1Very high69 Ų6932.1 Ų32.135%0.35416%0.164SC..Iπ-helixtrans-86.8-40.8-178.3-57-58.5000111.4W236 F658W236-I240 HydrophobicContact CD2-CB 4.33Å; W236-I240 HydrophobicContact CD2-CG1 3.64Å; W236-I240 HydrophobicContact CE3-CB 4.45Å; W236-I240 HydrophobicContact CE3-CD1 4.03Å; W236-I240 HydrophobicContact CE3-CG1 3.33Å; W236-I240 HydrophobicContact CG-CG1 4.4Å; W236-I240 HydrophobicContact CH2-CB 4.44Å; W236-I240 HydrophobicContact CH2-CD1 4.01Å; W236-I240 HydrophobicContact CH2-CG1 3.68Å; W236-I240 HydrophobicContact CH2-CG2 4.1Å; W236-I240 HydrophobicContact CZ2-CB 4.33Å; W236-I240 HydrophobicContact CZ2-CG1 3.98Å; W236-I240 HydrophobicContact CZ2-CG2 3.9Å; W236-I240 HydrophobicContact CZ3-CD1 3.63Å; W236-I240 HydrophobicContact CZ3-CG1 3.37Å; W236-I240 VanDerWaalsContact O-CB 3.29Å; W236-I240 WeakPolarHBondContact O-CB 3.44Å; W236-I240 PolarHBondContact O-N 3.42Å; I240-F658 HydrophobicContact CD1-CD2 4.17Å; I240-F658 HydrophobicContact CD1-CE2 3.77Å; I240-F658 HydrophobicContact CD1-CZ 4.34Å; I240-F658 HydrophobicContact CG1-CE2 4.3Å; I240-F658 HydrophobicContact CG1-CZ 4.38Å
241Y93.4Very high93.2Very high21 Ų2135.5 Ų35.58%0.08218%0.183CC..Iπ-helixtrans-103.3-58.5-176.7-52.5-79.4000111.7W236 E237 R243 G244 R316 H473 S474W236-Y241 AromaticContact CD1-CE2 3.72Å; W236-Y241 AromaticContact NE1-CE2 3.48Å; W236-Y241 AromaticContact NE1-CZ 3.84Å; W236-Y241 PolarHBondContact NE1-OH 3.12Å; E237-Y241 PolarHBondContact O-N 2.98Å; Y241-R243 PolarHBondContact O-N 3.32Å; Y241-G244 PolarHBondContact O-N 2.62Å; Y241-R316 PolarHBondContact O-NH1 3.49Å; Y241-R316 PolarHBondContact O-NH2 3.47Å; Y241-H473 HydrophobicContact CD1-CB 4.4Å; Y241-H473 HydrophobicContact CE1-CB 4.07Å; Y241-H473 AromaticContact CE1-CG 3.84Å; Y241-S474 VanDerWaalsContact CB-CB 3.45Å
242L94.1Very high93.3Very high12 Ų1236.3 Ų36.36%0.06319%0.189CC..Iπ-helixtrans-74.3-22.5-166.7-59.8179.1000114.2E237 E238 R245 R316 T322 D323 L325E237-L242 HydrophobicContact CG-CD1 4.02Å; E237-L242 HydrophobicContact CG-CG 4.44Å; E237-L242 WeakPolarHBondContact O-CG 3.23Å; E237-L242 PolarHBondContact O-N 2.97Å; E237-L242 VanDerWaalsContact O-N 3.16Å; E238-L242 CarbonylContact O-C 3.57Å; E238-L242 WeakPolarHBondContact O-CA 3.38Å; E238-L242 WeakPolarHBondContact O-CB 3.2Å; E238-L242 PolarHBondContact O-N 3.17Å; E238-L242 VanDerWaalsContact O-N 3.13Å; L242-R245 PolarHBondContact O-NH2 3.03Å; L242-R316 HydrophobicContact CD2-CG 4.3Å; L242-T322 HydrophobicContact CB-CG2 4.16Å; L242-D323 HydrophobicContact CB-CB 4.33Å; L242-D323 HydrophobicContact CD2-CB 4.05Å; L242-D323 PolarHBondContact O-N 3.26Å; L242-L325 HydrophobicContact CD2-CG 4.34Å
243R93.1Very high93.4Very high101 Ų10135.9 Ų35.938%0.38119%0.186SC..THydrogen-bonded Turntrans-95-9.2174.8-71.7-175.5180-1446.2114.1E238 Y239 Y241 R245 T322E238-R243 HydrophobicContact CG-CG 4.28Å; E238-R243 WeakPolarHBondContact O-CG 3.28Å; E238-R243 PolarHBondContact O-N 3.48Å; E238-R243 IonicContact OE1-CZ 3.67Å; E238-R243 VanDerWaalsContact OE1-CZ 3.24Å; E238-R243 IonicContact OE1-NE 3.62Å; E238-R243 PolarHBondContact OE1-NE 3.19Å; E238-R243 IonicContact OE1-NH2 3.82Å; E238-R243 PolarHBondContact OE1-NH2 3.02Å; Y239-R243 VanDerWaalsContact CD1-CD 3.47Å; Y239-R243 VanDerWaalsContact CE1-CZ 3.45Å; Y241-R243 PolarHBondContact O-N 3.32Å; R243-R245 PolarHBondContact O-N 3.36Å; R243-R245 PolarHBondContact O-NE 2.86Å; R243-T322 HydrophobicContact CG-CG2 3.84Å; R243-T322 WeakPolarHBondContact CG-OG1 3.12Å
244G90.9Very high93.8Very high32 Ų3235.7 Ų35.733%0.3318%0.183SC..  trans-60.2128168.900000110.3Y241Y241-G244 PolarHBondContact O-N 2.62Å
245R95.1Very high94.1Very high62 Ų6232.2 Ų32.223%0.23416%0.164CC..  trans-102.7-15.4-174.3-58.3-61.976-162.6-11.7114.4L242 R243 G319 E320 E321 D323 R388 V389L242-R245 PolarHBondContact O-NH2 3.03Å; R243-R245 PolarHBondContact O-N 3.36Å; R243-R245 PolarHBondContact O-NE 2.86Å; R245-G319 PolarHBondContact NH1-O 3.07Å; R245-E320 WeakPolarHBondContact CD-O 3.44Å; R245-E320 PolarHBondContact NH1-O 3.12Å; R245-E321 PolarHBondContact NH1-O 3Å; R245-D323 IonicContact CZ-OD1 2.98Å; R245-D323 IonicContact NH1-OD1 2.63Å; R245-D323 PolarHBondContact NH1-OD1 2.94Å; R245-D323 IonicContact NH2-OD1 3.55Å; R245-D323 PolarHBondContact NH2-OD1 3.28Å; R245-D323 IonicContact NH2-OD2 2.78Å; R245-R388 WeakPolarHBondContact O-CG 3.31Å; R245-R388 PolarHBondContact O-N 2.76Å; R245-V389 HydrophobicContact CB-CG2 4.49Å; R245-V389 HydrophobicContact CG-CG2 4.49Å
246G94.9Very high94.3Very high35 Ų3531.5 Ų31.536%0.36116%0.164SC..SBendtrans-75.1175175.200000113.2R388G246-R388 WeakPolarHBondContact O-CG 3.48Å
247P97.1Very high94.5Very high16 Ų1630.2 Ų30.210%0.10416%0.159CC..  trans-60.8134.3-178.8-25.939000111.9N251 A385 G386 D387 T536 L540P247-N251 WeakPolarHBondContact O-CB 3.1Å; P247-N251 PolarHBondContact O-ND2 3.43Å; P247-A385 WeakPolarHBondContact CB-O 3.41Å; P247-G386 WeakPolarHBondContact CA-O 3.3Å; P247-D387 VanDerWaalsContact CD-OD1 3.22Å; P247-D387 WeakPolarHBondContact CD-OD1 3.49Å; P247-T536 HydrophobicContact CG-CG2 4.19Å; P247-L540 HydrophobicContact CB-CD2 3.57Å; P247-L540 HydrophobicContact CG-CD2 4.01Å
248I96.9Very high94.6Very high7 Ų728.3 Ų28.34%0.03615%0.151CC..Hα-helixtrans-90.8-19.4-179.358.4168.5000113.5V250 S252 N253 F453 E472I248-V250 VanDerWaalsContact C-N 3.33Å; I248-V250 PolarHBondContact O-N 3.36Å; I248-S252 PolarHBondContact O-N 3.03Å; I248-N253 PolarHBondContact O-N 3.35Å; I248-N253 PolarHBondContact O-OD1 3.31Å; I248-F453 HydrophobicContact CD1-CB 4.48Å; I248-F453 HydrophobicContact CG1-CB 4.49Å; I248-E472 HydrophobicContact CD1-CG 4.32Å
249M95.9Very high94.7Very high0 Ų026 Ų260%014%0.14CC..Hα-helixtrans-51.1-46.2-174.6170.7-179.778.800113.7A385 H445 C448 F453 A537 A541M249-A385 HydrophobicContact SD-CB 4Å; M249-H445 HydrophobicContact CE-CB 3.64Å; M249-H445 HydrophobicContact CG-CB 3.74Å; M249-H445 HydrophobicContact SD-CB 3.41Å; M249-H445 WeakPolarHBondContact SD-CB 3.17Å; M249-C448 HydrophobicContact SD-CB 4.21Å; M249-F453 HydrophobicContact CB-CD1 3.99Å; M249-F453 HydrophobicContact CB-CD2 4.35Å; M249-F453 HydrophobicContact CB-CE1 4.06Å; M249-F453 HydrophobicContact CB-CE2 4.39Å; M249-F453 HydrophobicContact CB-CG 4.14Å; M249-F453 HydrophobicContact CB-CZ 4.23Å; M249-F453 HydrophobicContact CG-CD1 3.9Å; M249-F453 HydrophobicContact CG-CD2 4.47Å; M249-F453 HydrophobicContact CG-CE1 3.44Å; M249-F453 VanDerWaalsContact CG-CE1 3.44Å; M249-F453 HydrophobicContact CG-CE2 4.05Å; M249-F453 HydrophobicContact CG-CG 4.39Å; M249-F453 HydrophobicContact CG-CZ 3.5Å; M249-F453 HydrophobicContact SD-CE1 4.06Å; M249-F453 HydrophobicContact SD-CE2 3.76Å; M249-F453 HydrophobicContact SD-CZ 3.45Å; M249-F453 WeakPolarHBondContact SD-CZ 3.24Å; M249-A537 HydrophobicContact CE-CB 4.16Å; M249-A537 WeakPolarHBondContact CE-O 3.4Å; M249-A541 HydrophobicContact CE-CB 4.02Å
250V96.1Very high94.8Very high2 Ų223.6 Ų23.61%0.01213%0.13CC..Hα-helixtrans-103.8-42.1177.9169.30000111.2I248 S252 H445 L540 V544I248-V250 VanDerWaalsContact C-N 3.33Å; I248-V250 PolarHBondContact O-N 3.36Å; V250-S252 VanDerWaalsContact C-N 3.26Å; V250-S252 PolarHBondContact O-N 2.93Å; V250-H445 HydrophobicContact CG2-CB 4.43Å; V250-L540 HydrophobicContact CB-CD2 3.98Å; V250-L540 HydrophobicContact CB-CG 4.16Å; V250-L540 HydrophobicContact CG2-CD2 4.25Å; V250-L540 HydrophobicContact CG2-CG 4.17Å; V250-V544 HydrophobicContact CB-CG2 4.4Å; V250-V544 HydrophobicContact CG1-CG2 3.52Å; V250-V544 HydrophobicContact CG2-CG2 4.05Å
251N95.8Very high94.8Very high76 Ų7626.2 Ų26.241%0.40614%0.137SC..Hα-helixtrans-79.5-6.5-168.7-53.6-42.3000113.6P247P247-N251 WeakPolarHBondContact O-CB 3.1Å; P247-N251 PolarHBondContact O-ND2 3.43Å
252S96.2Very high94.6Very high21 Ų2126.4 Ų26.415%0.14714%0.139CC..THydrogen-bonded Turntrans-142.5-46.5-179.5-175.60000113.2I248 V250 H473I248-S252 PolarHBondContact O-N 3.03Å; V250-S252 VanDerWaalsContact C-N 3.26Å; V250-S252 PolarHBondContact O-N 2.93Å; S252-H473 VanDerWaalsContact O-CB 3.26Å; S252-H473 WeakPolarHBondContact O-CB 3.43Å
253N98.1Very high94.3Very high0 Ų028.3 Ų28.30%016%0.157CC..  trans-67.5149.9-178.4-71.623.1000110.5I248 F453 N470 A471 E472I248-N253 PolarHBondContact O-N 3.35Å; I248-N253 PolarHBondContact O-OD1 3.31Å; N253-F453 PolarHBondContact ND2-O 3.46Å; N253-N470 PolarHBondContact ND2-OD1 3.04Å; N253-A471 VanDerWaalsContact CA-O 3.23Å; N253-A471 WeakPolarHBondContact CA-O 3.39Å; N253-A471 WeakPolarHBondContact CB-O 3.46Å; N253-E472 WeakPolarHBondContact OD1-CA 3.43Å
254Y97.8Very high94.2Very high15 Ų1524.9 Ų24.96%0.05915%0.148CC..EExtended strand (participates in β ladder)trans-126164.5175.659.5-93.5000109.9N470 A471 H473 A478 V481 G708Y254-N470 CarbonylContact O-C 3.5Å; Y254-A471 HydrophobicContact CD2-CB 4.05Å; Y254-A471 HydrophobicContact CE1-CB 4.19Å; Y254-A471 HydrophobicContact CE2-CB 3.58Å; Y254-A471 PolarHBondContact N-O 3.38Å; Y254-A471 VanDerWaalsContact N-O 3.12Å; Y254-A471 PolarHBondContact O-N 3.5Å; Y254-H473 HydrophobicContact CD1-CB 4.03Å; Y254-H473 AromaticContact CD1-CD2 3.86Å; Y254-H473 AromaticContact CD1-CG 3.81Å; Y254-H473 HydrophobicContact CE1-CB 3.94Å; Y254-H473 AromaticContact CE1-CG 3.68Å; Y254-H473 AromaticContact CE1-ND1 3.72Å; Y254-A478 HydrophobicContact CD2-CB 4.43Å; Y254-A478 HydrophobicContact CE2-CB 4.08Å; Y254-V481 HydrophobicContact CE2-CB 4.21Å; Y254-V481 HydrophobicContact CE2-CG1 4.47Å; Y254-V481 HydrophobicContact CE2-CG2 4.3Å; Y254-V481 WeakPolarHBondContact OH-CG2 3.39Å; Y254-G708 WeakPolarHBondContact CA-O 3.44Å; Y254-G708 WeakPolarHBondContact CB-O 3.37Å
255F97.6Very high94.5Very high3 Ų323.8 Ų23.81%0.01314%0.135CC..EExtended strand (participates in β ladder)trans-123.2164.2-177.669.7-89000112.7M257 A440 L443 I444 L469 F546 G707 G708 H732F255-M257 HydrophobicContact CD2-CG 4.31Å; F255-M257 HydrophobicContact CE2-CE 3.84Å; F255-M257 HydrophobicContact CE2-CG 4.1Å; F255-A440 HydrophobicContact CE1-CB 4.28Å; F255-A440 HydrophobicContact CE2-CB 3.95Å; F255-A440 HydrophobicContact CZ-CB 3.57Å; F255-L443 HydrophobicContact CB-CB 3.76Å; F255-L443 HydrophobicContact CD2-CB 4Å; F255-L443 HydrophobicContact CD2-CD1 3.9Å; F255-L443 HydrophobicContact CG-CB 4.03Å; F255-I444 HydrophobicContact CD1-CB 3.7Å; F255-I444 HydrophobicContact CD1-CD1 4.16Å; F255-I444 HydrophobicContact CD1-CG1 4.13Å; F255-I444 HydrophobicContact CE1-CB 4.32Å; F255-I444 HydrophobicContact CE1-CD1 4.46Å; F255-I444 HydrophobicContact CG-CB 4.4Å; F255-L469 CarbonylContact C-O 3.54Å; F255-L469 WeakPolarHBondContact CA-O 3.46Å; F255-L469 VanDerWaalsContact CB-O 3.29Å; F255-L469 WeakPolarHBondContact CB-O 3.3Å; F255-F546 AromaticContact CE1-CE1 3.8Å; F255-F546 HydrophobicContact CE1-CE1 3.8Å; F255-F546 HydrophobicContact CE1-CZ 4.1Å; F255-F546 HydrophobicContact CZ-CE1 4.29Å; F255-G707 CarbonylContact O-C 3.59Å; F255-G707 WeakPolarHBondContact O-CA 3.48Å; F255-G708 WeakPolarHBondContact CD1-O 3.45Å; F255-G708 WeakPolarHBondContact CE1-O 3.5Å; F255-G708 PolarHBondContact N-O 3.12Å; F255-G708 PolarHBondContact O-N 3.06Å; F255-H732 AromaticContact CE2-ND1 3.96Å; F255-H732 AromaticContact CZ-ND1 3.82Å
256A96.6Very high94.5Very high13 Ų1325.7 Ų25.711%0.10715%0.153CC..EExtended strand (participates in β ladder)trans-136.8140.9170.700000110.9L443 G468 L469 G706A256-L443 WeakPolarHBondContact O-CD1 3.29Å; A256-G468 CarbonylContact O-C 3.58Å; A256-G468 WeakPolarHBondContact O-CA 3.47Å; A256-L469 HydrophobicContact CB-CB 4.26Å; A256-L469 PolarHBondContact N-O 2.93Å; A256-L469 PolarHBondContact O-N 2.63Å; A256-G706 WeakPolarHBondContact CA-O 3.4Å
257M95.6Very high94.7Very high0 Ų026.9 Ų26.90%015%0.151CC..EExtended strand (participates in β ladder)trans-98.1156.2-178.4-70.1-174.3174.200112.4F255 L436 Y439 A440 L443 W485 G706F255-M257 HydrophobicContact CD2-CG 4.31Å; F255-M257 HydrophobicContact CE2-CE 3.84Å; F255-M257 HydrophobicContact CE2-CG 4.1Å; M257-L436 WeakPolarHBondContact CE-O 3.36Å; M257-L436 HydrophobicContact SD-CD2 4.42Å; M257-Y439 HydrophobicContact CB-CE1 3.78Å; M257-Y439 HydrophobicContact CE-CD1 3.76Å; M257-Y439 HydrophobicContact CE-CE1 4.37Å; M257-Y439 HydrophobicContact CE-CG 4.23Å; M257-Y439 HydrophobicContact CG-CD1 3.96Å; M257-Y439 HydrophobicContact CG-CE1 3.59Å; M257-Y439 HydrophobicContact SD-CD1 3.68Å; M257-Y439 HydrophobicContact SD-CE1 3.76Å; M257-A440 HydrophobicContact CE-CB 3.62Å; M257-L443 HydrophobicContact CB-CD1 4.4Å; M257-L443 HydrophobicContact CG-CD1 3.65Å; M257-W485 PolarHBondContact O-NE1 3Å; M257-G706 PolarHBondContact N-O 3.43Å
258D94.4Very high94.8Very high1 Ų126.9 Ų26.91%0.00515%0.15CC..  trans-65.2-175.6170-160.5-2.2000111.4R271 Y439 M467 S705D258-R271 IonicContact OD1-NH2 3.86Å; D258-R271 PolarHBondContact OD1-NH2 3.41Å; D258-R271 IonicContact OD2-NH2 3.37Å; D258-R271 PolarHBondContact OD2-NH2 3.46Å; D258-R271 VanDerWaalsContact OD2-NH2 3.17Å; D258-Y439 WeakPolarHBondContact CB-OH 3.38Å; D258-Y439 PolarHBondContact N-OH 3.31Å; D258-M467 HydrophobicContact CB-CG 4.1Å; D258-M467 WeakPolarHBondContact CB-O 3.5Å; D258-M467 PolarHBondContact N-O 3.15Å; D258-M467 WeakPolarHBondContact OD1-CE 3.5Å; D258-M467 WeakPolarHBondContact OD2-CG 3.16Å; D258-S705 PolarHBondContact O-N 2.92Å
259F92.4Very high94.9Very high3 Ų326.6 Ų26.61%0.01315%0.148CC..BIsolated β-bridgetrans-57.4139.6163.9-60.1-53.4000111.8L262 K466 M489 I694 M702 L703F259-L262 HydrophobicContact CB-CB 3.74Å; F259-L262 HydrophobicContact CD2-CB 4.13Å; F259-L262 HydrophobicContact CD2-CD2 3.72Å; F259-L262 HydrophobicContact CD2-CG 4.25Å; F259-L262 HydrophobicContact CE2-CD2 4.01Å; F259-L262 HydrophobicContact CG-CB 4.19Å; F259-L262 HydrophobicContact CG-CD2 4.36Å; F259-K466 PolarHBondContact O-NZ 3.2Å; F259-M489 HydrophobicContact CD1-CE 4.46Å; F259-M489 HydrophobicContact CD1-SD 4.4Å; F259-M489 HydrophobicContact CD2-SD 4.47Å; F259-M489 HydrophobicContact CE1-CB 4.26Å; F259-M489 HydrophobicContact CE1-CE 4.02Å; F259-M489 HydrophobicContact CE1-SD 4.22Å; F259-M489 HydrophobicContact CE2-CB 3.69Å; F259-M489 HydrophobicContact CE2-CG 4.44Å; F259-M489 HydrophobicContact CE2-SD 4.34Å; F259-M489 HydrophobicContact CZ-CB 3.47Å; F259-M489 VanDerWaalsContact CZ-CB 3.47Å; F259-M489 HydrophobicContact CZ-CE 4.34Å; F259-M489 HydrophobicContact CZ-CG 4.39Å; F259-M489 HydrophobicContact CZ-SD 4.21Å; F259-I694 HydrophobicContact CE1-CD1 3.92Å; F259-I694 HydrophobicContact CZ-CD1 4.23Å; F259-M702 HydrophobicContact CD1-CB 4.15Å; F259-M702 WeakPolarHBondContact CD1-O 3.44Å; F259-M702 HydrophobicContact CE1-CB 3.63Å; F259-M702 HydrophobicContact CE1-CE 4.25Å; F259-M702 HydrophobicContact CE1-CG 4.29Å; F259-M702 WeakPolarHBondContact CE1-O 3.39Å; F259-M702 HydrophobicContact CE2-CE 4.28Å; F259-M702 HydrophobicContact CE2-CG 4.46Å; F259-M702 HydrophobicContact CZ-CB 3.88Å; F259-M702 HydrophobicContact CZ-CE 3.52Å; F259-M702 HydrophobicContact CZ-CG 4.05Å; F259-L703 CarbonylContact C-O 3.46Å; F259-L703 VanDerWaalsContact CA-O 3.28Å; F259-L703 WeakPolarHBondContact CA-O 3.13Å
260L90Very high95Very high6 Ų626.6 Ų26.63%0.03115%0.148CC..SBendtrans-63.2-58.6-177.8-174.961.2000110.2Y427 L436 K466 L550 L703 S705L260-Y427 HydrophobicContact CD1-CD2 3.72Å; L260-Y427 HydrophobicContact CD1-CE2 4.46Å; L260-Y427 HydrophobicContact CD1-CG 3.83Å; L260-Y427 HydrophobicContact CG-CG 4.45Å; L260-L436 HydrophobicContact CD1-CD1 4.4Å; L260-L436 HydrophobicContact CD1-CD2 3.96Å; L260-K466 PolarHBondContact O-NZ 2.91Å; L260-L550 HydrophobicContact CD2-CD2 3.95Å; L260-L703 HydrophobicContact CB-CD2 4.49Å; L260-L703 HydrophobicContact CD2-CD2 3.93Å; L260-L703 PolarHBondContact N-O 2.91Å; L260-S705 WeakPolarHBondContact CD1-OG 3.28Å
261Y88.4Confident95.1Very high125 Ų12526.5 Ų26.549%0.4915%0.148SC..SBendtrans-100.2-21.4-173.6-53.7-55.5000114.5Y427 L550 L703Y261-Y427 HydrophobicContact CD1-CD1 4.01Å; Y261-Y427 AromaticContact CD1-CE1 3.93Å; Y261-Y427 HydrophobicContact CD1-CE1 3.93Å; Y261-Y427 HydrophobicContact CE1-CD1 4.06Å; Y261-Y427 AromaticContact CE1-CE1 3.64Å; Y261-Y427 HydrophobicContact CE1-CE1 3.64Å; Y261-Y427 AromaticContact CE1-CZ 3.94Å; Y261-L550 VanDerWaalsContact OH-CD2 3.3Å; Y261-L550 WeakPolarHBondContact OH-CD2 3.39Å; Y261-L703 HydrophobicContact CE2-CD2 4.02Å
262L89.1Confident95.2Very high24 Ų2422.9 Ų22.913%0.12613%0.128CC..  trans-86.5132.2-174.6-174.862.4000111.2F259 P264 K466 Y493 E701 M702F259-L262 HydrophobicContact CB-CB 3.74Å; F259-L262 HydrophobicContact CD2-CB 4.13Å; F259-L262 HydrophobicContact CD2-CD2 3.72Å; F259-L262 HydrophobicContact CD2-CG 4.25Å; F259-L262 HydrophobicContact CE2-CD2 4.01Å; F259-L262 HydrophobicContact CG-CB 4.19Å; F259-L262 HydrophobicContact CG-CD2 4.36Å; L262-P264 HydrophobicContact CD2-CG 4.36Å; L262-P264 HydrophobicContact CG-CG 4.03Å; L262-K466 PolarHBondContact O-NZ 3.26Å; L262-Y493 HydrophobicContact CD1-CE2 3.81Å; L262-Y493 HydrophobicContact CD2-CD1 4.09Å; L262-Y493 HydrophobicContact CD2-CD2 3.77Å; L262-Y493 HydrophobicContact CD2-CE1 4.03Å; L262-Y493 HydrophobicContact CD2-CE2 3.71Å; L262-Y493 HydrophobicContact CD2-CG 3.94Å; L262-Y493 HydrophobicContact CG-CD2 4.49Å; L262-Y493 HydrophobicContact CG-CE2 4.25Å; L262-E701 HydrophobicContact CD1-CG 4.43Å; L262-E701 HydrophobicContact CD2-CG 4.23Å; L262-M702 HydrophobicContact CD2-CG 4.16Å
263A88.2Confident95.3Very high53 Ų5321.9 Ų21.944%0.43812%0.121SC..  trans-136.690.7172.100000108.8T265A263-T265 VanDerWaalsContact C-N 3.25Å; A263-T265 PolarHBondContact O-N 3.35Å
264P92.1Very high95.3Very high29 Ų2922 Ų2219%0.18812%0.122CC..SBendtrans-62.3-25-173.8-30.841.4000115.6L262 Y493 Y498L262-P264 HydrophobicContact CD2-CG 4.36Å; L262-P264 HydrophobicContact CG-CG 4.03Å; P264-Y493 HydrophobicContact CB-CD2 4.3Å; P264-Y493 HydrophobicContact CG-CD2 3.82Å; P264-Y493 HydrophobicContact CG-CE2 4.44Å; P264-Y498 HydrophobicContact CB-CD2 3.8Å; P264-Y498 HydrophobicContact CB-CE2 3.46Å; P264-Y498 VanDerWaalsContact CB-CE2 3.46Å
265T96.3Very high95.4Very high9 Ų921.3 Ų21.36%0.05512%0.119CC..  trans-156.2151.8170.9-1770000109A263 L267 A270 R271 Y498 G502A263-T265 VanDerWaalsContact C-N 3.25Å; A263-T265 PolarHBondContact O-N 3.35Å; T265-L267 PolarHBondContact OG1-N 3.13Å; T265-A270 HydrophobicContact CG2-CB 4.15Å; T265-R271 HydrophobicContact CG2-CB 3.91Å; T265-Y498 HydrophobicContact CG2-CD1 3.85Å; T265-Y498 HydrophobicContact CG2-CE1 3.36Å; T265-Y498 HydrophobicContact CG2-CE2 4.3Å; T265-Y498 HydrophobicContact CG2-CG 4.48Å; T265-G502 WeakPolarHBondContact CB-O 3.42Å; T265-G502 PolarHBondContact OG1-O 3.15Å
266T96.1Very high95.4Very high101 Ų10121.1 Ų21.162%0.6212%0.118SC*.SBendtrans-92-9.4171.355.20000112.5Q268 N464T266-Q268 PolarHBondContact O-N 3.1Å; T266-N464 WeakPolarHBondContact CA-O 3.34Å; T266-N464 CarbonylContact O-C 3.5Å
267L98.4Very high95.5Very high60 Ų6021.6 Ų21.631%0.31412%0.118SC..  trans-77.9108.6179.8-60.4-178000110.2T265 A269 A270 R271 H503T265-L267 PolarHBondContact OG1-N 3.13Å; L267-A269 VanDerWaalsContact C-N 3.34Å; L267-A269 PolarHBondContact O-N 3.13Å; L267-A270 HydrophobicContact CB-CB 3.73Å; L267-A270 PolarHBondContact O-N 3.26Å; L267-A270 VanDerWaalsContact O-N 3.14Å; L267-R271 PolarHBondContact O-N 3.04Å; L267-H503 WeakPolarHBondContact CD1-ND1 3.18Å
268Q98.4Very high95.6Very high17 Ų1721.7 Ų21.78%0.07912%0.119CC..Hα-helixtrans-53-47.2-179.3-177.8176.83400113T266 R271 A272 L367 L420 D421 V461 F462T266-Q268 PolarHBondContact O-N 3.1Å; Q268-R271 PolarHBondContact O-N 2.92Å; Q268-A272 VanDerWaalsContact O-CB 3.32Å; Q268-A272 WeakPolarHBondContact O-CB 3.47Å; Q268-A272 PolarHBondContact O-N 3.34Å; Q268-L367 HydrophobicContact CB-CD1 4.37Å; Q268-L367 HydrophobicContact CG-CD1 4.39Å; Q268-L367 VanDerWaalsContact OE1-CD2 3.28Å; Q268-L420 HydrophobicContact CG-CD2 4.44Å; Q268-D421 PolarHBondContact NE2-O 3.29Å; Q268-V461 HydrophobicContact CG-CG1 3.99Å; Q268-V461 PolarHBondContact NE2-O 3.45Å; Q268-F462 WeakPolarHBondContact CG-O 3.26Å
269A98.7Very high95.8Very high1 Ų121.8 Ų21.81%0.00812%0.119CC..Hα-helixtrans-64.4-40.5179.600000112.4L267 A272 G273 E360 M363 Q364 L367L267-A269 VanDerWaalsContact C-N 3.34Å; L267-A269 PolarHBondContact O-N 3.13Å; A269-A272 PolarHBondContact O-N 2.99Å; A269-G273 PolarHBondContact O-N 3.17Å; A269-E360 HydrophobicContact CB-CG 4.07Å; A269-M363 HydrophobicContact CB-CB 4.05Å; A269-Q364 HydrophobicContact CB-CB 4.06Å; A269-L367 HydrophobicContact CB-CD1 3.98Å
270A98.6Very high96.1Very high0 Ų021.8 Ų21.80%012%0.12CC..Hα-helixtrans-65.2-47.5177.800000110.8T265 L267 A272 G273 N274 E360 Y498 G502 C504T265-A270 HydrophobicContact CG2-CB 4.15Å; L267-A270 HydrophobicContact CB-CB 3.73Å; L267-A270 PolarHBondContact O-N 3.26Å; L267-A270 VanDerWaalsContact O-N 3.14Å; A270-A272 VanDerWaalsContact C-N 3.32Å; A270-A272 PolarHBondContact O-N 3.27Å; A270-G273 PolarHBondContact O-N 3.11Å; A270-G273 VanDerWaalsContact O-N 3.13Å; A270-N274 PolarHBondContact O-N 3.13Å; A270-N274 VanDerWaalsContact O-N 3.11Å; A270-E360 VanDerWaalsContact CA-CD 3.48Å; A270-E360 WeakPolarHBondContact CA-OE1 3.22Å; A270-E360 HydrophobicContact CB-CG 4.44Å; A270-E360 VanDerWaalsContact CB-OE1 3.23Å; A270-E360 WeakPolarHBondContact CB-OE1 3.36Å; A270-Y498 HydrophobicContact CB-CD1 4.36Å; A270-Y498 HydrophobicContact CB-CE1 4.09Å; A270-G502 WeakPolarHBondContact CB-O 3.23Å; A270-C504 PolarHBondContact O-SG 3.03Å
271R98.2Very high96.5Very high0 Ų023.6 Ų23.60%013%0.129CC..Hα-helixtrans-56.5-49.3176.1-165.884.9168.4138.8-4.3111.1D258 T265 L267 Q268 G273 N274 I275 V461 G465 M467 E492 Y498D258-R271 IonicContact OD1-NH2 3.86Å; D258-R271 PolarHBondContact OD1-NH2 3.41Å; D258-R271 IonicContact OD2-NH2 3.37Å; D258-R271 PolarHBondContact OD2-NH2 3.46Å; D258-R271 VanDerWaalsContact OD2-NH2 3.17Å; T265-R271 HydrophobicContact CG2-CB 3.91Å; L267-R271 PolarHBondContact O-N 3.04Å; Q268-R271 PolarHBondContact O-N 2.92Å; R271-G273 VanDerWaalsContact C-N 3.32Å; R271-G273 PolarHBondContact O-N 3.45Å; R271-N274 PolarHBondContact O-N 3.44Å; R271-I275 WeakPolarHBondContact O-CB 3.42Å; R271-I275 WeakPolarHBondContact O-CG2 3.46Å; R271-I275 PolarHBondContact O-N 3.26Å; R271-V461 HydrophobicContact CB-CG1 4.18Å; R271-V461 HydrophobicContact CG-CG1 4.33Å; R271-G465 VanDerWaalsContact CD-O 3.3Å; R271-G465 WeakPolarHBondContact CD-O 3.34Å; R271-G465 WeakPolarHBondContact CG-O 3.41Å; R271-G465 PolarHBondContact NE-O 3.49Å; R271-M467 HydrophobicContact CG-SD 4.17Å; R271-M467 VanDerWaalsContact CZ-CE 3.43Å; R271-E492 IonicContact CZ-OE1 2.66Å; R271-E492 IonicContact CZ-OE2 3.28Å; R271-E492 IonicContact NE-OE1 3.83Å; R271-E492 IonicContact NH1-OE1 3.58Å; R271-E492 PolarHBondContact NH1-OE1 3.08Å; R271-E492 IonicContact NH1-OE2 2.99Å; R271-E492 PolarHBondContact NH1-OE2 3.29Å; R271-E492 IonicContact NH2-OE2 2.67Å; R271-E492 PolarHBondContact NH2-OE2 2.91Å; R271-Y498 WeakPolarHBondContact CA-OH 3.47Å
272A98.7Very high96.9Very high0 Ų018.1 Ų18.10%011%0.108CC..Hα-helixtrans-58.9-42.8176.600000111.9Q268 A269 A270 I276 M363 L420 V461Q268-A272 VanDerWaalsContact O-CB 3.32Å; Q268-A272 WeakPolarHBondContact O-CB 3.47Å; Q268-A272 PolarHBondContact O-N 3.34Å; A269-A272 PolarHBondContact O-N 2.99Å; A270-A272 VanDerWaalsContact C-N 3.32Å; A270-A272 PolarHBondContact O-N 3.27Å; A272-I276 HydrophobicContact CB-CD1 4.3Å; A272-I276 WeakPolarHBondContact O-CB 3.38Å; A272-I276 VanDerWaalsContact O-CD1 3.3Å; A272-I276 WeakPolarHBondContact O-CD1 3.4Å; A272-I276 WeakPolarHBondContact O-CG1 3.48Å; A272-I276 PolarHBondContact O-N 3.36Å; A272-M363 HydrophobicContact CB-CB 4.37Å; A272-M363 HydrophobicContact CB-CG 3.75Å; A272-M363 HydrophobicContact CB-SD 4.46Å; A272-L420 HydrophobicContact CB-CD2 3.92Å; A272-V461 HydrophobicContact CB-CG1 4.38Å; A272-V461 HydrophobicContact CB-CG2 4.14Å
273G98.4Very high97.2Very high0 Ų017.2 Ų17.20%010%0.103CC..Hα-helixtrans-56.7-52.217900000113.4A269 A270 R271 H277A269-G273 PolarHBondContact O-N 3.17Å; A270-G273 PolarHBondContact O-N 3.11Å; A270-G273 VanDerWaalsContact O-N 3.13Å; R271-G273 VanDerWaalsContact C-N 3.32Å; R271-G273 PolarHBondContact O-N 3.45Å; G273-H277 WeakPolarHBondContact O-CB 3.34Å; G273-H277 PolarHBondContact O-N 3.19Å; G273-H277 VanDerWaalsContact O-N 3.16Å
274N98.4Very high97.5Very high2 Ų219.5 Ų19.51%0.01110%0.103CC..Hα-helixtrans-68.9-46.6179.9-100-12.1000112.5A270 R271 I276 H277 A278 P356 E492 L496 G497 Y498 C504A270-N274 PolarHBondContact O-N 3.13Å; A270-N274 VanDerWaalsContact O-N 3.11Å; R271-N274 PolarHBondContact O-N 3.44Å; N274-I276 PolarHBondContact O-N 3.09Å; N274-H277 WeakPolarHBondContact O-CB 3.48Å; N274-H277 PolarHBondContact O-N 3.49Å; N274-A278 WeakPolarHBondContact O-CB 3.48Å; N274-A278 PolarHBondContact O-N 2.82Å; N274-P356 WeakPolarHBondContact OD1-CB 3.24Å; N274-P356 WeakPolarHBondContact OD1-CG 3.3Å; N274-E492 HydrophobicContact CB-CG 4.09Å; N274-L496 HydrophobicContact CB-CD1 4.35Å; N274-L496 WeakPolarHBondContact O-CD1 3.44Å; N274-G497 PolarHBondContact ND2-O 3.04Å; N274-Y498 HydrophobicContact CB-CE1 4.23Å; N274-Y498 WeakPolarHBondContact CB-OH 3.35Å; N274-Y498 WeakPolarHBondContact ND2-CE1 3.23Å; N274-Y498 PolarHBondContact ND2-OH 3.18Å; N274-C504 VanDerWaalsContact CG-SG 3.57Å
275I98.3Very high97.7Very high0 Ų022 Ų220%011%0.111CC..Hα-helixtrans-67.1-40.8-176.6-157.374.8000111.8R271 H277 A278 I279 L459 M467 V488 E492R271-I275 WeakPolarHBondContact O-CB 3.42Å; R271-I275 WeakPolarHBondContact O-CG2 3.46Å; R271-I275 PolarHBondContact O-N 3.26Å; I275-H277 VanDerWaalsContact C-N 3.31Å; I275-H277 PolarHBondContact O-N 2.81Å; I275-A278 PolarHBondContact O-N 3.07Å; I275-I279 VanDerWaalsContact O-CG1 3.28Å; I275-I279 WeakPolarHBondContact O-CG1 3.39Å; I275-I279 PolarHBondContact O-N 3.43Å; I275-L459 HydrophobicContact CG1-CD1 4.48Å; I275-L459 HydrophobicContact CG2-CD1 4.22Å; I275-L459 HydrophobicContact CG2-CD2 3.56Å; I275-L459 HydrophobicContact CG2-CG 4.48Å; I275-M467 HydrophobicContact CB-SD 4.03Å; I275-M467 HydrophobicContact CD1-CE 3.44Å; I275-M467 VanDerWaalsContact CD1-CE 3.44Å; I275-M467 HydrophobicContact CD1-SD 3.65Å; I275-M467 HydrophobicContact CG1-CE 4.09Å; I275-M467 HydrophobicContact CG1-SD 3.58Å; I275-M467 VanDerWaalsContact CG1-SD 3.58Å; I275-M467 HydrophobicContact CG2-SD 4.29Å; I275-V488 HydrophobicContact CD1-CG1 3.32Å; I275-V488 HydrophobicContact CG1-CG1 3.69Å; I275-E492 HydrophobicContact CD1-CB 4.28Å
276I98.8Very high97.6Very high0 Ų022.3 Ų22.30%011%0.112CC..Hα-helixtrans-61.4-44174.6-69.9167.9000109.2A272 N274 A278 I279 L280 I334 L347 I359 M363 F416 V418 L459A272-I276 HydrophobicContact CB-CD1 4.3Å; A272-I276 WeakPolarHBondContact O-CB 3.38Å; A272-I276 VanDerWaalsContact O-CD1 3.3Å; A272-I276 WeakPolarHBondContact O-CD1 3.4Å; A272-I276 WeakPolarHBondContact O-CG1 3.48Å; A272-I276 PolarHBondContact O-N 3.36Å; N274-I276 PolarHBondContact O-N 3.09Å; I276-A278 PolarHBondContact O-N 3.32Å; I276-I279 PolarHBondContact O-N 3.01Å; I276-L280 HydrophobicContact CG2-CD1 3.91Å; I276-L280 WeakPolarHBondContact O-CD1 3.39Å; I276-L280 WeakPolarHBondContact O-CG 3.38Å; I276-L280 PolarHBondContact O-N 3.34Å; I276-I334 HydrophobicContact CD1-CD1 3.96Å; I276-I334 HydrophobicContact CG2-CD1 4.16Å; I276-L347 HydrophobicContact CG2-CD2 4.42Å; I276-I359 HydrophobicContact CB-CG2 4.06Å; I276-I359 HydrophobicContact CD1-CG2 4.04Å; I276-I359 HydrophobicContact CG2-CD1 4.1Å; I276-I359 HydrophobicContact CG2-CG2 3.92Å; I276-M363 HydrophobicContact CD1-CG 4.43Å; I276-M363 HydrophobicContact CD1-SD 3.86Å; I276-F416 HydrophobicContact CG1-CE2 4.35Å; I276-F416 HydrophobicContact CG1-CZ 4.41Å; I276-F416 HydrophobicContact CG2-CZ 4.06Å; I276-V418 HydrophobicContact CD1-CG1 4.36Å; I276-V418 HydrophobicContact CD1-CG2 4.2Å; I276-V418 HydrophobicContact CG1-CG2 4.39Å; I276-L459 HydrophobicContact CG1-CD2 3.81Å
277H98.5Very high97.4Very high23 Ų2319.3 Ų19.311%0.1069%0.092CC..Hα-helixtrans-60.5-45.8176.2-165.883.3000112.1G273 N274 I275 I279 L280 L281 L354 P356 I359 L496G273-H277 WeakPolarHBondContact O-CB 3.34Å; G273-H277 PolarHBondContact O-N 3.19Å; G273-H277 VanDerWaalsContact O-N 3.16Å; N274-H277 WeakPolarHBondContact O-CB 3.48Å; N274-H277 PolarHBondContact O-N 3.49Å; I275-H277 VanDerWaalsContact C-N 3.31Å; I275-H277 PolarHBondContact O-N 2.81Å; H277-I279 PolarHBondContact O-N 3.47Å; H277-L280 WeakPolarHBondContact O-CB 3.25Å; H277-L280 PolarHBondContact O-N 2.63Å; H277-L280 VanDerWaalsContact O-N 3.08Å; H277-L281 WeakPolarHBondContact O-CG 3.46Å; H277-L281 PolarHBondContact O-N 2.99Å; H277-L354 PolarHBondContact CE1-O 3.31Å; H277-L354 PolarHBondContact ND1-O 3.25Å; H277-P356 HydrophobicContact CB-CB 4.48Å; H277-P356 HydrophobicContact CB-CG 3.92Å; H277-I359 HydrophobicContact CB-CD1 3.95Å; H277-L496 HydrophobicContact CB-CD1 4.42Å
278A98.4Very high97.2Very high2 Ų220.7 Ų20.72%0.0179%0.093CC..Hα-helixtrans-61-42.3177.600000112.2N274 I275 I276 L280 L281 Y282 V488 T491 L496N274-A278 WeakPolarHBondContact O-CB 3.48Å; N274-A278 PolarHBondContact O-N 2.82Å; I275-A278 PolarHBondContact O-N 3.07Å; I276-A278 PolarHBondContact O-N 3.32Å; A278-L280 VanDerWaalsContact C-N 3.27Å; A278-L280 PolarHBondContact O-N 2.74Å; A278-L281 WeakPolarHBondContact O-CB 3.23Å; A278-L281 PolarHBondContact O-N 3.24Å; A278-Y282 PolarHBondContact O-N 3.09Å; A278-V488 HydrophobicContact CB-CG1 4.05Å; A278-T491 HydrophobicContact CB-CG2 4.15Å; A278-L496 HydrophobicContact CB-CD1 4.1Å
279I98.6Very high97Very high2 Ų221 Ų211%0.0110%0.095CC..Hα-helixtrans-58.2-40.6172.5-68.9168.7000110.8I275 I276 H277 Y282 R283 F312 F416 F457 L459 V488I275-I279 VanDerWaalsContact O-CG1 3.28Å; I275-I279 WeakPolarHBondContact O-CG1 3.39Å; I275-I279 PolarHBondContact O-N 3.43Å; I276-I279 PolarHBondContact O-N 3.01Å; H277-I279 PolarHBondContact O-N 3.47Å; I279-Y282 WeakPolarHBondContact O-CB 3.43Å; I279-Y282 PolarHBondContact O-N 3.44Å; I279-R283 WeakPolarHBondContact O-CB 3.37Å; I279-R283 PolarHBondContact O-N 2.62Å; I279-F312 HydrophobicContact CG2-CE1 3.45Å; I279-F312 VanDerWaalsContact CG2-CE1 3.45Å; I279-F312 HydrophobicContact CG2-CZ 3.9Å; I279-F416 HydrophobicContact CB-CE1 4.31Å; I279-F416 HydrophobicContact CB-CZ 4.14Å; I279-F416 HydrophobicContact CD1-CE2 4.07Å; I279-F416 HydrophobicContact CD1-CZ 4.16Å; I279-F416 HydrophobicContact CG2-CD1 3.96Å; I279-F416 HydrophobicContact CG2-CE1 3.48Å; I279-F416 VanDerWaalsContact CG2-CE1 3.48Å; I279-F416 HydrophobicContact CG2-CE2 4.44Å; I279-F416 HydrophobicContact CG2-CZ 3.73Å; I279-F457 HydrophobicContact CG2-CZ 4.31Å; I279-L459 HydrophobicContact CD1-CD2 4.02Å; I279-V488 HydrophobicContact CB-CG2 4.42Å; I279-V488 HydrophobicContact CD1-CG1 4.48Å; I279-V488 HydrophobicContact CG1-CB 4.38Å; I279-V488 HydrophobicContact CG1-CG1 3.65Å; I279-V488 HydrophobicContact CG1-CG2 3.82Å
280L97.7Very high96.8Very high3 Ų326.2 Ų26.22%0.01612%0.119CC..Hα-helixtrans-72.1-32.8179.5-64.8166.7000112.9I276 H277 A278 R283 K284 L347 L353 I359 F416I276-L280 HydrophobicContact CG2-CD1 3.91Å; I276-L280 WeakPolarHBondContact O-CD1 3.39Å; I276-L280 WeakPolarHBondContact O-CG 3.38Å; I276-L280 PolarHBondContact O-N 3.34Å; H277-L280 WeakPolarHBondContact O-CB 3.25Å; H277-L280 PolarHBondContact O-N 2.63Å; H277-L280 VanDerWaalsContact O-N 3.08Å; A278-L280 VanDerWaalsContact C-N 3.27Å; A278-L280 PolarHBondContact O-N 2.74Å; L280-R283 PolarHBondContact O-N 3.08Å; L280-K284 WeakPolarHBondContact O-CB 2.89Å; L280-K284 PolarHBondContact O-N 2.77Å; L280-L347 HydrophobicContact CD1-CB 4.33Å; L280-L347 HydrophobicContact CD1-CD1 4.3Å; L280-L347 HydrophobicContact CD1-CD2 3.58Å; L280-L347 HydrophobicContact CD1-CG 4.26Å; L280-L347 HydrophobicContact CD2-CD1 3.53Å; L280-L347 HydrophobicContact CD2-CD2 4.33Å; L280-L347 HydrophobicContact CD2-CG 4.38Å; L280-L353 HydrophobicContact CB-CD1 3.89Å; L280-L353 HydrophobicContact CB-CD2 3.71Å; L280-L353 HydrophobicContact CB-CG 4.38Å; L280-L353 HydrophobicContact CD1-CD1 3.73Å; L280-L353 HydrophobicContact CD1-CD2 4.46Å; L280-L353 HydrophobicContact CD1-CG 4.36Å; L280-L353 HydrophobicContact CG-CD1 4.25Å; L280-I359 HydrophobicContact CD1-CD1 4.42Å; L280-F416 HydrophobicContact CD2-CE1 4.09Å
281L97.6Very high96.6Very high45 Ų4526.9 Ų26.924%0.23612%0.122CC..Hα-helixtrans-64.1-43.1169.5-67178.8000111H277 A278 K284 K285 L353 T491H277-L281 WeakPolarHBondContact O-CG 3.46Å; H277-L281 PolarHBondContact O-N 2.99Å; A278-L281 WeakPolarHBondContact O-CB 3.23Å; A278-L281 PolarHBondContact O-N 3.24Å; L281-K284 WeakPolarHBondContact O-CB 3.18Å; L281-K284 PolarHBondContact O-N 3.2Å; L281-K285 WeakPolarHBondContact O-CG 3.32Å; L281-K285 PolarHBondContact O-N 2.77Å; L281-L353 HydrophobicContact CD2-CD2 4.48Å; L281-T491 HydrophobicContact CD1-CG2 4.22Å
282Y97.5Very high96.3Very high10 Ų1035.1 Ų35.14%0.03916%0.158CC..Hα-helixtrans-60.4-49.5173.5-172.6-80.4000111.4A278 I279 K284 K285 L286 I291 W308 M311 F312 H483 L484 N487A278-Y282 PolarHBondContact O-N 3.09Å; I279-Y282 WeakPolarHBondContact O-CB 3.43Å; I279-Y282 PolarHBondContact O-N 3.44Å; Y282-K284 VanDerWaalsContact C-N 3.26Å; Y282-K284 PolarHBondContact O-N 3.15Å; Y282-K285 WeakPolarHBondContact O-CB 3.5Å; Y282-K285 PolarHBondContact O-N 2.96Å; Y282-K285 VanDerWaalsContact O-N 3.09Å; Y282-L286 PolarHBondContact O-N 2.92Å; Y282-I291 HydrophobicContact CD1-CD1 4.19Å; Y282-I291 HydrophobicContact CE1-CD1 3.57Å; Y282-I291 HydrophobicContact CE2-CD1 4.03Å; Y282-I291 VanDerWaalsContact CZ-CD1 3.49Å; Y282-W308 AromaticContact CZ-NE1 3.91Å; Y282-W308 PolarHBondContact OH-NE1 2.94Å; Y282-M311 HydrophobicContact CD1-SD 4.25Å; Y282-M311 HydrophobicContact CE1-CE 4.22Å; Y282-M311 HydrophobicContact CE1-SD 3.59Å; Y282-M311 VanDerWaalsContact CE1-SD 3.59Å; Y282-F312 HydrophobicContact CD1-CE2 4.06Å; Y282-F312 HydrophobicContact CD1-CZ 4.19Å; Y282-F312 HydrophobicContact CE1-CE2 4.49Å; Y282-H483 AromaticContact CE2-CE1 3.67Å; Y282-H483 AromaticContact CE2-ND1 3.48Å; Y282-H483 WeakPolarHBondContact CE2-ND1 3.37Å; Y282-H483 AromaticContact CZ-CE1 3.92Å; Y282-H483 AromaticContact CZ-ND1 3.61Å; Y282-H483 PolarHBondContact OH-CE1 3.15Å; Y282-H483 VanDerWaalsContact OH-CE1 3.29Å; Y282-H483 PolarHBondContact OH-ND1 3.46Å; Y282-L484 HydrophobicContact CD1-CD1 3.33Å; Y282-L484 HydrophobicContact CD2-CD1 4.02Å; Y282-L484 HydrophobicContact CE1-CB 4.34Å; Y282-L484 HydrophobicContact CE1-CD1 3.71Å; Y282-L484 HydrophobicContact CE2-CD1 4.33Å; Y282-L484 HydrophobicContact CG-CD1 3.5Å; Y282-L484 VanDerWaalsContact CG-CD1 3.5Å; Y282-N487 HydrophobicContact CD2-CB 3.84Å; Y282-N487 HydrophobicContact CE2-CB 3.94Å
283R96.2Very high96.1Very high5 Ų535.8 Ų35.82%0.01916%0.162CC..Hα-helixtrans-56.5-39.6176.1-176.1178.1175.9-139.4-5.2112I279 L280 L286 D287 F312 N313 S331I279-R283 WeakPolarHBondContact O-CB 3.37Å; I279-R283 PolarHBondContact O-N 2.62Å; L280-R283 PolarHBondContact O-N 3.08Å; R283-L286 WeakPolarHBondContact O-CB 3.47Å; R283-L286 PolarHBondContact O-N 2.81Å; R283-D287 WeakPolarHBondContact O-CB 3.34Å; R283-D287 PolarHBondContact O-N 3.12Å; R283-F312 HydrophobicContact CB-CD1 4.4Å; R283-F312 HydrophobicContact CB-CD2 4.03Å; R283-F312 HydrophobicContact CB-CE1 4.12Å; R283-F312 HydrophobicContact CB-CE2 3.74Å; R283-F312 HydrophobicContact CB-CG 4.34Å; R283-F312 HydrophobicContact CB-CZ 3.8Å; R283-F312 HydrophobicContact CG-CB 4.36Å; R283-F312 HydrophobicContact CG-CD1 4.23Å; R283-F312 HydrophobicContact CG-CD2 3.74Å; R283-F312 HydrophobicContact CG-CE1 4.45Å; R283-F312 HydrophobicContact CG-CE2 4.02Å; R283-F312 HydrophobicContact CG-CG 3.85Å; R283-F312 HydrophobicContact CG-CZ 4.36Å; R283-N313 PolarHBondContact NE-OD1 3.29Å; R283-N313 VanDerWaalsContact NH2-CG 3.34Å; R283-N313 PolarHBondContact NH2-ND2 3.07Å; R283-N313 PolarHBondContact NH2-OD1 2.86Å; R283-S331 PolarHBondContact NH1-O 3.25Å; R283-S331 PolarHBondContact NH2-O 2.93Å
284K93.8Very high95.8Very high100 Ų10037.5 Ų37.544%0.43517%0.171SC..Hα-helixtrans-64.6-44.3175.5-178.3-178.1176.3-175.10111.9L280 L281 Y282 L286 D287 R288L280-K284 WeakPolarHBondContact O-CB 2.89Å; L280-K284 PolarHBondContact O-N 2.77Å; L281-K284 WeakPolarHBondContact O-CB 3.18Å; L281-K284 PolarHBondContact O-N 3.2Å; Y282-K284 VanDerWaalsContact C-N 3.26Å; Y282-K284 PolarHBondContact O-N 3.15Å; K284-L286 VanDerWaalsContact C-N 3.31Å; K284-D287 PolarHBondContact O-N 3.31Å; K284-R288 WeakPolarHBondContact O-CB 3.44Å; K284-R288 VanDerWaalsContact O-CG 3.31Å; K284-R288 WeakPolarHBondContact O-CG 3.39Å; K284-R288 PolarHBondContact O-N 2.64Å; K284-R288 VanDerWaalsContact O-N 3.15Å
285K95.6Very high95.5Very high83 Ų8339.9 Ų39.936%0.36118%0.183SC..Hα-helixtrans-60.9-42.1174.2-70.6173.8-178.7172.20110.7L281 Y282 R288 Q289 E290 I291L281-K285 WeakPolarHBondContact O-CG 3.32Å; L281-K285 PolarHBondContact O-N 2.77Å; Y282-K285 WeakPolarHBondContact O-CB 3.5Å; Y282-K285 PolarHBondContact O-N 2.96Å; Y282-K285 VanDerWaalsContact O-N 3.09Å; K285-R288 CarbonylContact O-C 3.59Å; K285-R288 PolarHBondContact O-N 2.94Å; K285-Q289 PolarHBondContact O-N 2.89Å; K285-E290 HydrophobicContact CB-CB 4.35Å; K285-E290 PolarHBondContact O-N 3.36Å; K285-I291 HydrophobicContact CB-CG1 3.97Å
286L95.1Very high95.1Very high15 Ų1542.1 Ų42.18%0.07920%0.195CC..Hα-helixtrans-62.5-50.9176.2173.856.4000112.4L164 Y282 R283 K284 R288 Q289 I291 W308 M311 F312L164-L286 HydrophobicContact CD2-CD1 3.44Å; L164-L286 VanDerWaalsContact CD2-CD1 3.44Å; Y282-L286 PolarHBondContact O-N 2.92Å; R283-L286 WeakPolarHBondContact O-CB 3.47Å; R283-L286 PolarHBondContact O-N 2.81Å; K284-L286 VanDerWaalsContact C-N 3.31Å; L286-R288 PolarHBondContact O-N 3.37Å; L286-R288 VanDerWaalsContact O-N 3.15Å; L286-Q289 WeakPolarHBondContact O-CA 3.46Å; L286-Q289 PolarHBondContact O-N 2.75Å; L286-I291 HydrophobicContact CB-CD1 3.71Å; L286-I291 HydrophobicContact CD1-CD1 4.26Å; L286-W308 HydrophobicContact CD1-CB 3.74Å; L286-W308 HydrophobicContact CD1-CG 4.12Å; L286-M311 HydrophobicContact CD2-CB 4.3Å; L286-M311 HydrophobicContact CD2-SD 4.32Å; L286-F312 HydrophobicContact CD2-CD2 3.79Å; L286-F312 HydrophobicContact CD2-CE2 3.89Å
287D92Very high94.4Very high38 Ų3844.6 Ų44.620%0.20321%0.208CC..Hα-helixtrans-57.3-31.5178.5-99.5-25.8000112.3K41 R45 R283 K284K41-D287 WeakPolarHBondContact CE-OD2 3.46Å; K41-D287 IonicContact NZ-OD1 3.84Å; K41-D287 IonicContact NZ-OD2 2.96Å; K41-D287 PolarHBondContact NZ-OD2 3.16Å; R45-D287 IonicContact CZ-OD1 3.07Å; R45-D287 IonicContact NE-OD1 3.24Å; R45-D287 IonicContact NH2-OD1 2.77Å; R45-D287 PolarHBondContact NH2-OD1 3.32Å; R45-D287 IonicContact NH2-OD2 3.32Å; R283-D287 WeakPolarHBondContact O-CB 3.34Å; R283-D287 PolarHBondContact O-N 3.12Å; K284-D287 PolarHBondContact O-N 3.31Å
288R92.8Very high93.3Very high88 Ų8846.5 Ų46.533%0.33223%0.234SC..THydrogen-bonded Turntrans-91.1-0.5176.6-65.1-179172.9-168.7-6.7113.8I44 N48 M163 K284 K285 L286 E290I44-R288 HydrophobicContact CG2-CG 4.27Å; N48-R288 PolarHBondContact ND2-O 2.94Å; M163-R288 WeakPolarHBondContact CE-O 3.45Å; K284-R288 WeakPolarHBondContact O-CB 3.44Å; K284-R288 VanDerWaalsContact O-CG 3.31Å; K284-R288 WeakPolarHBondContact O-CG 3.39Å; K284-R288 PolarHBondContact O-N 2.64Å; K284-R288 VanDerWaalsContact O-N 3.15Å; K285-R288 CarbonylContact O-C 3.59Å; K285-R288 PolarHBondContact O-N 2.94Å; L286-R288 PolarHBondContact O-N 3.37Å; L286-R288 VanDerWaalsContact O-N 3.15Å; R288-E290 HydrophobicContact CB-CB 4.5Å; R288-E290 HydrophobicContact CB-CG 3.72Å; R288-E290 VanDerWaalsContact CD-OE1 3.25Å; R288-E290 WeakPolarHBondContact CD-OE1 3.4Å; R288-E290 IonicContact NH1-OE1 3.6Å; R288-E290 PolarHBondContact O-N 3.42Å
289Q94.9Very high92.5Very high25 Ų2550.5 Ų50.512%0.11726%0.262CS..THydrogen-bonded Turntrans54.930.6-176-47.3178.816.900113.5T52 M163 L164 Y165 K285 L286T52-Q289 VanDerWaalsContact CG2-OE1 3.27Å; M163-Q289 HydrophobicContact CB-CB 4.31Å; M163-Q289 HydrophobicContact CE-CB 3.83Å; L164-Q289 HydrophobicContact CB-CB 4.04Å; L164-Q289 PolarHBondContact N-O 2.86Å; Y165-Q289 HydrophobicContact CD2-CB 4.49Å; Y165-Q289 VanDerWaalsContact CD2-CD 3.41Å; Y165-Q289 HydrophobicContact CD2-CG 3.72Å; Y165-Q289 HydrophobicContact CE2-CG 3.87Å; K285-Q289 PolarHBondContact O-N 2.89Å; L286-Q289 WeakPolarHBondContact O-CA 3.46Å; L286-Q289 PolarHBondContact O-N 2.75Å
290E95.1Very high92.1Very high109 Ų10950.6 Ų50.651%0.50926%0.263SS..  trans-84.4-11.9-179.9-70.2168.8174.800112.3K285 R288 K292K285-E290 HydrophobicContact CB-CB 4.35Å; K285-E290 PolarHBondContact O-N 3.36Å; R288-E290 HydrophobicContact CB-CB 4.5Å; R288-E290 HydrophobicContact CB-CG 3.72Å; R288-E290 VanDerWaalsContact CD-OE1 3.25Å; R288-E290 WeakPolarHBondContact CD-OE1 3.4Å; R288-E290 IonicContact NH1-OE1 3.6Å; R288-E290 PolarHBondContact O-N 3.42Å; E290-K292 PolarHBondContact O-N 3.47Å
291I94.6Very high91.9Very high14 Ų1450.8 Ų50.87%0.07226%0.264CS..SBendtrans-64.4129.3168.2-59.5175.7000107.9L164 Y282 K285 L286L164-I291 WeakPolarHBondContact CA-O 2.98Å; L164-I291 VanDerWaalsContact CB-O 3.31Å; L164-I291 WeakPolarHBondContact CB-O 3.49Å; L164-I291 HydrophobicContact CD1-CB 4.15Å; L164-I291 HydrophobicContact CD1-CG2 4.02Å; L164-I291 HydrophobicContact CD2-CB 4.3Å; L164-I291 PolarHBondContact N-O 3.18Å; Y282-I291 HydrophobicContact CD1-CD1 4.19Å; Y282-I291 HydrophobicContact CE1-CD1 3.57Å; Y282-I291 HydrophobicContact CE2-CD1 4.03Å; Y282-I291 VanDerWaalsContact CZ-CD1 3.49Å; K285-I291 HydrophobicContact CB-CG1 3.97Å; L286-I291 HydrophobicContact CB-CD1 3.71Å; L286-I291 HydrophobicContact CD1-CD1 4.26Å
292K92.4Very high91.7Very high174 Ų17448.7 Ų48.776%0.75725%0.253SS*.PPolyproline II helixtrans-71.2140.7-179.2-67.5-178.2179.51760110.1E290E290-K292 PolarHBondContact O-N 3.47Å
293P92.9Very high91.7Very high14 Ų1448.5 Ų48.59%0.09125%0.252CS..PPolyproline II helixtrans-62.2143.5171.128-34.1000110.1P162 F167 L295P162-P293 HydrophobicContact CB-CG 4.03Å; P162-P293 HydrophobicContact CG-CG 3.99Å; F167-P293 HydrophobicContact CD2-CB 4.3Å; F167-P293 HydrophobicContact CD2-CG 4.24Å; F167-P293 HydrophobicContact CE2-CG 4.1Å; P293-L295 HydrophobicContact CB-CD2 4.47Å; P293-L295 HydrophobicContact CG-CD2 4.43Å
294I92.3Very high91.7Very high36 Ų3648.4 Ų48.419%0.18525%0.253CS..PPolyproline II helixtrans-75.6127.9174.3-59.2179.5000108.3L303 W308I294-L303 HydrophobicContact CB-CB 4.42Å; I294-L303 HydrophobicContact CB-CD1 4.32Å; I294-L303 HydrophobicContact CG2-CD1 3.78Å; I294-L303 HydrophobicContact CG2-CG 4.34Å; I294-L303 PolarHBondContact O-N 3.45Å; I294-W308 HydrophobicContact CD1-CH2 3.84Å
295L91.9Very high91.8Very high51 Ų5143.8 Ų43.827%0.26723%0.233SC..EExtended strand (participates in β ladder)trans-124126.4-178.3-55.7178.8000110.5F167 P293 V301 P302F167-L295 HydrophobicContact CE2-CD2 4.05Å; P293-L295 HydrophobicContact CB-CD2 4.47Å; P293-L295 HydrophobicContact CG-CD2 4.43Å; L295-V301 CarbonylContact C-O 3.42Å; L295-V301 VanDerWaalsContact CA-O 3.28Å; L295-V301 WeakPolarHBondContact CA-O 3.44Å; L295-P302 VanDerWaalsContact CD2-CA 3.47Å; L295-P302 HydrophobicContact CD2-CB 3.63Å
296L89.8Confident91.8Very high47 Ų4740.8 Ų40.825%0.24622%0.224CC..Hα-helixtrans-83.4169.6170.8-57.2-178.7000111.4W135 G298 T300 V301 L303 M593 L596 M648W135-L296 HydrophobicContact CH2-CD1 4.3Å; L296-G298 PolarHBondContact O-N 3.31Å; L296-T300 PolarHBondContact O-N 3.43Å; L296-V301 HydrophobicContact CB-CB 4.27Å; L296-V301 PolarHBondContact N-O 2.49Å; L296-V301 PolarHBondContact O-N 2.94Å; L296-V301 VanDerWaalsContact O-N 3.08Å; L296-L303 HydrophobicContact CD1-CD2 3.87Å; L296-L303 HydrophobicContact CD2-CD1 4.33Å; L296-L303 HydrophobicContact CG-CD1 4.35Å; L296-L303 HydrophobicContact CG-CD2 4.1Å; L296-L303 HydrophobicContact CG-CG 4.23Å; L296-M593 HydrophobicContact CD1-CE 4.25Å; L296-L596 HydrophobicContact CD1-CD2 4.24Å; L296-M648 HydrophobicContact CD1-CE 4.32Å
297L83.7Confident91.8Very high52 Ų5240.8 Ų40.827%0.27222%0.223SC..Hα-helixtrans54.154.5172.5-157.971.8000113.3W135 L143 W150 M151 T300 V301W135-L297 HydrophobicContact CD2-CD2 4.44Å; W135-L297 HydrophobicContact CE3-CD1 4.48Å; W135-L297 HydrophobicContact CE3-CD2 4.07Å; L143-L297 HydrophobicContact CD2-CD1 4.24Å; W150-L297 HydrophobicContact CZ3-CD2 4.17Å; M151-L297 HydrophobicContact CE-CD2 3.69Å; M151-L297 HydrophobicContact CE-CG 3.75Å; M151-L297 HydrophobicContact CG-CD2 3.92Å; M151-L297 HydrophobicContact SD-CD2 3.5Å; M151-L297 VanDerWaalsContact SD-CD2 3.5Å; M151-L297 HydrophobicContact SD-CG 4.11Å; L297-T300 WeakPolarHBondContact O-CB 3.41Å; L297-T300 PolarHBondContact O-OG1 3.18Å; L297-V301 HydrophobicContact CB-CG2 4.43Å
298G75.4Confident92Very high63 Ų6339.1 Ų39.165%0.64921%0.214SC*.Hα-helixtrans61.950.4176.600000113L296L296-G298 PolarHBondContact O-N 3.31Å
299S82.8Confident91.9Very high87 Ų8740.1 Ų40.161%0.60822%0.223SC*.Hα-helixtrans68.336178.8-53.80000115.6
300T89.2Confident91.9Very high4 Ų443.2 Ų43.23%0.02523%0.233CC..THydrogen-bonded Turntrans-112.5-46.7-176.6-49.60000113.2M151 V154 K155 L296 L297M151-T300 HydrophobicContact CB-CG2 4.09Å; M151-T300 HydrophobicContact CE-CG2 4.31Å; M151-T300 VanDerWaalsContact CE-OG1 3.29Å; M151-T300 WeakPolarHBondContact CE-OG1 3.24Å; M151-T300 HydrophobicContact CG-CG2 4.09Å; V154-T300 HydrophobicContact CB-CG2 3.96Å; V154-T300 HydrophobicContact CG1-CG2 3.79Å; V154-T300 WeakPolarHBondContact CG1-O 3.5Å; K155-T300 WeakPolarHBondContact CE-OG1 3.36Å; K155-T300 HydrophobicContact CG-CG2 4.32Å; L296-T300 PolarHBondContact O-N 3.43Å; L297-T300 WeakPolarHBondContact O-CB 3.41Å; L297-T300 PolarHBondContact O-OG1 3.18Å
301V93.4Very high91.9Very high7 Ų738 Ų384%0.04221%0.209CC..EExtended strand (participates in β ladder)trans-105112-171.1-176.60000110.3W135 W150 L295 L296 L297 L596W135-V301 HydrophobicContact CH2-CG2 4.42Å; W135-V301 HydrophobicContact CZ2-CB 4.35Å; W135-V301 HydrophobicContact CZ2-CG1 3.96Å; W135-V301 HydrophobicContact CZ2-CG2 4Å; W150-V301 HydrophobicContact CH2-CG2 3.52Å; W150-V301 HydrophobicContact CZ2-CG2 4.44Å; W150-V301 HydrophobicContact CZ3-CG2 4.24Å; L295-V301 CarbonylContact C-O 3.42Å; L295-V301 VanDerWaalsContact CA-O 3.28Å; L295-V301 WeakPolarHBondContact CA-O 3.44Å; L296-V301 HydrophobicContact CB-CB 4.27Å; L296-V301 PolarHBondContact N-O 2.49Å; L296-V301 PolarHBondContact O-N 2.94Å; L296-V301 VanDerWaalsContact O-N 3.08Å; L297-V301 HydrophobicContact CB-CG2 4.43Å; V301-L596 HydrophobicContact CG1-CD2 3.74Å
302P95.3Very high92.1Very high1 Ų137.8 Ų37.81%0.00621%0.207CC..EExtended strand (participates in β ladder)trans-73.7145.3-179.931.8-35.8000112.7L130 F167 L171 L295L130-P302 HydrophobicContact CD1-CG 3.87Å; L130-P302 HydrophobicContact CD2-CG 4.23Å; F167-P302 HydrophobicContact CB-CB 3.83Å; F167-P302 HydrophobicContact CB-CG 3.91Å; F167-P302 HydrophobicContact CD1-CB 4.04Å; F167-P302 HydrophobicContact CD1-CG 3.64Å; F167-P302 HydrophobicContact CD2-CB 3.57Å; F167-P302 HydrophobicContact CD2-CG 4.14Å; F167-P302 HydrophobicContact CE1-CB 4.48Å; F167-P302 HydrophobicContact CE1-CG 4.12Å; F167-P302 HydrophobicContact CE2-CB 4.06Å; F167-P302 HydrophobicContact CG-CB 3.55Å; F167-P302 HydrophobicContact CG-CG 3.64Å; F167-P302 HydrophobicContact CZ-CB 4.48Å; L171-P302 HydrophobicContact CD2-CG 4.09Å; L295-P302 VanDerWaalsContact CD2-CA 3.47Å; L295-P302 HydrophobicContact CD2-CB 3.63Å
303L95.7Very high92.3Very high5 Ų529.7 Ų29.73%0.02617%0.173CC..PPolyproline II helixtrans-96.7153.3166.1-61.4-174.5000111.1I294 L296 M593 R595 L596I294-L303 HydrophobicContact CB-CB 4.42Å; I294-L303 HydrophobicContact CB-CD1 4.32Å; I294-L303 HydrophobicContact CG2-CD1 3.78Å; I294-L303 HydrophobicContact CG2-CG 4.34Å; I294-L303 PolarHBondContact O-N 3.45Å; L296-L303 HydrophobicContact CD1-CD2 3.87Å; L296-L303 HydrophobicContact CD2-CD1 4.33Å; L296-L303 HydrophobicContact CG-CD1 4.35Å; L296-L303 HydrophobicContact CG-CD2 4.1Å; L296-L303 HydrophobicContact CG-CG 4.23Å; L303-M593 HydrophobicContact CD1-CE 3.83Å; L303-M593 HydrophobicContact CD1-SD 3.86Å; L303-M593 HydrophobicContact CD2-CE 4.36Å; L303-R595 CarbonylContact C-O 3.54Å; L303-R595 WeakPolarHBondContact CA-O 3.48Å; L303-R595 HydrophobicContact CB-CB 4.13Å; L303-R595 HydrophobicContact CD2-CB 4.25Å; L303-L596 HydrophobicContact CD2-CD2 3.82Å; L303-L596 HydrophobicContact CD2-CG 4.34Å
304C96.8Very high92.5Very high4 Ų429 Ų293%0.02717%0.168CC..PPolyproline II helixtrans-61.4139172.7-176.40000111.2Q168 L171 A306 R595 F597 E599Q168-C304 PolarHBondContact OE1-SG 2.8Å; L171-C304 HydrophobicContact CD1-CB 3.79Å; C304-A306 PolarHBondContact SG-N 3.27Å; C304-R595 HydrophobicContact CB-CB 4.32Å; C304-R595 WeakPolarHBondContact CB-O 3.47Å; C304-R595 PolarHBondContact N-O 2.86Å; C304-R595 VanDerWaalsContact O-CZ 3.31Å; C304-R595 PolarHBondContact O-NE 3.36Å; C304-R595 PolarHBondContact O-NH2 2.94Å; C304-F597 VanDerWaalsContact CB-O 3.32Å; C304-F597 WeakPolarHBondContact CB-O 3.09Å; C304-E599 PolarHBondContact SG-N 2.88Å
305S96.4Very high92.8Very high2 Ų227.3 Ų27.31%0.01416%0.16CC..  trans-113.52.7-178.3-48.20000112.2L164 Y165 Q307 W308L164-S305 WeakPolarHBondContact O-CB 3.43Å; L164-S305 PolarHBondContact O-OG 3.15Å; Y165-S305 WeakPolarHBondContact CE1-O 3.24Å; S305-Q307 PolarHBondContact O-N 3Å; S305-Q307 VanDerWaalsContact O-N 3.11Å; S305-W308 WeakPolarHBondContact O-CB 3.37Å; S305-W308 PolarHBondContact O-N 3.34Å
306A95Very high93.1Very high21 Ų2125 Ų2517%0.17415%0.147CC..G310 helixtrans-56.2-33.7-171.500000113.6C304 W308 E309 E599C304-A306 PolarHBondContact SG-N 3.27Å; A306-W308 PolarHBondContact O-N 3.5Å; A306-W308 VanDerWaalsContact O-N 3.13Å; A306-E309 WeakPolarHBondContact O-CB 3.36Å; A306-E309 WeakPolarHBondContact O-CG 3.4Å; A306-E309 PolarHBondContact O-N 3.47Å; A306-E309 VanDerWaalsContact O-N 3.08Å; A306-E599 HydrophobicContact CB-CG 4.02Å
307Q95.3Very high93.5Very high14 Ų1423.3 Ų23.37%0.06514%0.138CC..G310 helixtrans-61-24.1-179.8-59.7-171.742.200113.3S305 E309 W475 A476 D477 I480 G600S305-Q307 PolarHBondContact O-N 3Å; S305-Q307 VanDerWaalsContact O-N 3.11Å; Q307-E309 VanDerWaalsContact C-N 3.25Å; Q307-E309 PolarHBondContact O-N 2.94Å; Q307-W475 VanDerWaalsContact O-CZ3 3.29Å; Q307-W475 WeakPolarHBondContact O-CZ3 3.48Å; Q307-A476 HydrophobicContact CB-CB 4.02Å; Q307-D477 PolarHBondContact NE2-OD2 3.49Å; Q307-D477 PolarHBondContact OE1-OD2 3.26Å; Q307-I480 HydrophobicContact CB-CD1 4Å; Q307-I480 HydrophobicContact CB-CG1 3.79Å; Q307-I480 HydrophobicContact CB-CG2 4.28Å; Q307-I480 HydrophobicContact CG-CG1 4.38Å; Q307-I480 VanDerWaalsContact OE1-CG1 3.25Å; Q307-G600 PolarHBondContact NE2-O 2.94Å
308W95.6Very high94.2Very high3 Ų321.3 Ų21.31%0.01113%0.128CC..G310 helixtrans-66.6-24.1176.2-90.8-91.5000113.8L164 Y282 L286 I294 S305 A306 R310 M311 I480 H483L164-W308 HydrophobicContact CD2-CB 4.17Å; L164-W308 HydrophobicContact CD2-CG 4.27Å; Y282-W308 AromaticContact CZ-NE1 3.91Å; Y282-W308 PolarHBondContact OH-NE1 2.94Å; L286-W308 HydrophobicContact CD1-CB 3.74Å; L286-W308 HydrophobicContact CD1-CG 4.12Å; I294-W308 HydrophobicContact CD1-CH2 3.84Å; S305-W308 WeakPolarHBondContact O-CB 3.37Å; S305-W308 PolarHBondContact O-N 3.34Å; A306-W308 PolarHBondContact O-N 3.5Å; A306-W308 VanDerWaalsContact O-N 3.13Å; W308-R310 PolarHBondContact O-N 2.92Å; W308-M311 HydrophobicContact CG-CE 4.33Å; W308-M311 PolarHBondContact O-N 3.38Å; W308-I480 HydrophobicContact CD2-CG2 4.08Å; W308-I480 HydrophobicContact CE3-CD1 3.8Å; W308-I480 HydrophobicContact CE3-CG2 4.25Å; W308-I480 HydrophobicContact CH2-CD1 3.46Å; W308-I480 VanDerWaalsContact CH2-CD1 3.46Å; W308-I480 HydrophobicContact CZ2-CD1 4.28Å; W308-I480 HydrophobicContact CZ2-CG2 4.36Å; W308-I480 HydrophobicContact CZ3-CD1 3.19Å; W308-I480 HydrophobicContact CZ3-CG2 4.49Å; W308-H483 HydrophobicContact CZ2-CB 4.06Å; W308-H483 AromaticContact CZ2-CD2 3.83Å; W308-H483 AromaticContact CZ2-CG 3.85Å
309E92.4Very high95.3Very high110 Ų11019.2 Ų19.251%0.51411%0.107SC..G310 helixtrans-59.8-34.7-174-67.9-178.3179.500112.4Y165 A306 Q307 H327Y165-E309 HydrophobicContact CE1-CG 3.99Å; Y165-E309 WeakPolarHBondContact OH-CG 3.49Å; A306-E309 WeakPolarHBondContact O-CB 3.36Å; A306-E309 WeakPolarHBondContact O-CG 3.4Å; A306-E309 PolarHBondContact O-N 3.47Å; A306-E309 VanDerWaalsContact O-N 3.08Å; Q307-E309 VanDerWaalsContact C-N 3.25Å; Q307-E309 PolarHBondContact O-N 2.94Å; E309-H327 PolarHBondContact O-CE1 3.21Å
310R93.7Very high95.9Very high90 Ų9019.5 Ų19.534%0.3410%0.098SC..G310 helixtrans-101.35.7-174.1-63.2-178.8-174.7178.6-1.5114E237 W308 F312 T314 T456 W475E237-R310 IonicContact OE1-CZ 3.92Å; E237-R310 IonicContact OE1-NH1 2.87Å; E237-R310 PolarHBondContact OE1-NH1 2.98Å; E237-R310 IonicContact OE2-CZ 2.76Å; E237-R310 IonicContact OE2-NH1 3.86Å; E237-R310 PolarHBondContact OE2-NH1 3.47Å; W308-R310 PolarHBondContact O-N 2.92Å; R310-F312 VanDerWaalsContact C-N 3.34Å; R310-F312 PolarHBondContact O-N 2.9Å; R310-T314 HydrophobicContact CB-CG2 4.4Å; R310-T314 VanDerWaalsContact O-CB 3.28Å; R310-T314 WeakPolarHBondContact O-CB 3.43Å; R310-T314 PolarHBondContact O-OG1 2.8Å; R310-T456 WeakPolarHBondContact O-CG2 3.43Å; R310-W475 HydrophobicContact CB-CB 4.22Å; R310-W475 HydrophobicContact CB-CE3 4.15Å
311M95.9Very high96.2Very high0 Ų027.1 Ų27.10%013%0.134CC..SBendtrans-58.7-40.2-174.4-178.6-179.8-74.400114.3Y282 L286 W308 T456 F457 W475 I480 L484Y282-M311 HydrophobicContact CD1-SD 4.25Å; Y282-M311 HydrophobicContact CE1-CE 4.22Å; Y282-M311 HydrophobicContact CE1-SD 3.59Å; Y282-M311 VanDerWaalsContact CE1-SD 3.59Å; L286-M311 HydrophobicContact CD2-CB 4.3Å; L286-M311 HydrophobicContact CD2-SD 4.32Å; W308-M311 HydrophobicContact CG-CE 4.33Å; W308-M311 PolarHBondContact O-N 3.38Å; M311-T456 PolarHBondContact O-OG1 3.37Å; M311-F457 HydrophobicContact CG-CE1 4.43Å; M311-W475 HydrophobicContact CB-CH2 3.82Å; M311-W475 HydrophobicContact CB-CZ3 3.69Å; M311-W475 HydrophobicContact CE-CH2 4.41Å; M311-W475 HydrophobicContact CG-CH2 3.83Å; M311-W475 HydrophobicContact CG-CZ3 4.23Å; M311-I480 HydrophobicContact CE-CG2 3.62Å; M311-L484 HydrophobicContact CE-CB 4.12Å; M311-L484 HydrophobicContact CG-CD2 4.42Å; M311-L484 HydrophobicContact SD-CB 4.04Å; M311-L484 HydrophobicContact SD-CD1 4.2Å; M311-L484 HydrophobicContact SD-CD2 3.99Å; M311-L484 HydrophobicContact SD-CG 4.31Å
312F97.4Very high96.3Very high8 Ų828.8 Ų28.84%0.03514%0.144CC..SBendtrans-117159.1-180-61.9-83.4000110.9I279 Y282 R283 L286 R310 T314 H327 A415 F416 F457 L484I279-F312 HydrophobicContact CG2-CE1 3.45Å; I279-F312 VanDerWaalsContact CG2-CE1 3.45Å; I279-F312 HydrophobicContact CG2-CZ 3.9Å; Y282-F312 HydrophobicContact CD1-CE2 4.06Å; Y282-F312 HydrophobicContact CD1-CZ 4.19Å; Y282-F312 HydrophobicContact CE1-CE2 4.49Å; R283-F312 HydrophobicContact CB-CD1 4.4Å; R283-F312 HydrophobicContact CB-CD2 4.03Å; R283-F312 HydrophobicContact CB-CE1 4.12Å; R283-F312 HydrophobicContact CB-CE2 3.74Å; R283-F312 HydrophobicContact CB-CG 4.34Å; R283-F312 HydrophobicContact CB-CZ 3.8Å; R283-F312 HydrophobicContact CG-CB 4.36Å; R283-F312 HydrophobicContact CG-CD1 4.23Å; R283-F312 HydrophobicContact CG-CD2 3.74Å; R283-F312 HydrophobicContact CG-CE1 4.45Å; R283-F312 HydrophobicContact CG-CE2 4.02Å; R283-F312 HydrophobicContact CG-CG 3.85Å; R283-F312 HydrophobicContact CG-CZ 4.36Å; L286-F312 HydrophobicContact CD2-CD2 3.79Å; L286-F312 HydrophobicContact CD2-CE2 3.89Å; R310-F312 VanDerWaalsContact C-N 3.34Å; R310-F312 PolarHBondContact O-N 2.9Å; F312-T314 PolarHBondContact O-N 3.16Å; F312-T314 PolarHBondContact O-OG1 3.24Å; F312-H327 PolarHBondContact O-CE1 3.47Å; F312-H327 VanDerWaalsContact O-CE1 3.24Å; F312-H327 PolarHBondContact O-ND1 2.84Å; F312-A415 WeakPolarHBondContact CA-O 3.39Å; F312-F416 HydrophobicContact CD1-CD1 4.1Å; F312-F416 HydrophobicContact CE1-CD1 4.17Å; F312-F457 HydrophobicContact CD1-CE1 4.01Å; F312-F457 HydrophobicContact CD1-CZ 4.02Å; F312-F457 AromaticContact CE1-CE1 3.88Å; F312-F457 HydrophobicContact CE1-CE1 3.88Å; F312-F457 AromaticContact CE1-CZ 3.61Å; F312-F457 HydrophobicContact CE1-CZ 3.61Å; F312-F457 HydrophobicContact CZ-CZ 4.44Å; F312-L484 HydrophobicContact CZ-CD1 3.97Å; F312-L484 HydrophobicContact CZ-CD2 4.39Å
313N96.6Very high96.4Very high5 Ų528.8 Ų28.83%0.02714%0.144CC..SBendtrans60.826.1175.9-35.5-29.9000113.3R283 V328 S331 A415R283-N313 PolarHBondContact NE-OD1 3.29Å; R283-N313 VanDerWaalsContact NH2-CG 3.34Å; R283-N313 PolarHBondContact NH2-ND2 3.07Å; R283-N313 PolarHBondContact NH2-OD1 2.86Å; N313-V328 HydrophobicContact CB-CG2 3.71Å; N313-V328 WeakPolarHBondContact CB-O 3.45Å; N313-V328 PolarHBondContact ND2-O 3.34Å; N313-V328 PolarHBondContact O-N 2.91Å; N313-S331 VanDerWaalsContact OD1-CB 3.31Å; N313-S331 WeakPolarHBondContact OD1-CB 3.09Å; N313-A415 PolarHBondContact N-O 2.77Å; N313-A415 WeakPolarHBondContact OD1-CA 3.44Å
314T98.1Very high96.5Very high0 Ų032.4 Ų32.40%017%0.166CC..EExtended strand (participates in β ladder)trans-122144.2-179.4-44.60000109.1R310 F312 L325 Q326 H327 K455 T456R310-T314 HydrophobicContact CB-CG2 4.4Å; R310-T314 VanDerWaalsContact O-CB 3.28Å; R310-T314 WeakPolarHBondContact O-CB 3.43Å; R310-T314 PolarHBondContact O-OG1 2.8Å; F312-T314 PolarHBondContact O-N 3.16Å; F312-T314 PolarHBondContact O-OG1 3.24Å; T314-L325 HydrophobicContact CG2-CB 4.35Å; T314-L325 HydrophobicContact CG2-CD2 4.13Å; T314-Q326 CarbonylContact C-O 3.5Å; T314-Q326 WeakPolarHBondContact CA-O 3.34Å; T314-Q326 WeakPolarHBondContact CG2-O 3.24Å; T314-H327 HydrophobicContact CG2-CB 4.22Å; T314-H327 PolarHBondContact OG1-ND1 3.03Å; T314-K455 WeakPolarHBondContact O-CE 3.28Å; T314-T456 VanDerWaalsContact CB-CG2 3.44Å; T314-T456 HydrophobicContact CG2-CG2 3.98Å
315S98.3Very high96.5Very high0 Ų033.6 Ų33.60%017%0.172CC..EExtended strand (participates in β ladder)trans-140.9146.2169.8-47.10000108.9Q326 E412 D454 K455S315-Q326 PolarHBondContact N-O 3.04Å; S315-Q326 PolarHBondContact O-N 3.11Å; S315-E412 WeakPolarHBondContact OG-CA 3.33Å; S315-E412 PolarHBondContact OG-O 2.88Å; S315-D454 CarbonylContact C-O 3.57Å; S315-D454 WeakPolarHBondContact CA-O 3.42Å; S315-K455 PolarHBondContact OG-NZ 3.02Å
316R98.5Very high96.4Very high2 Ų236.2 Ų36.21%0.00818%0.184CC..EExtended strand (participates in β ladder)trans-74.7132.9165.1-176171.2172.3160.2-1.6108.7Y241 L242 D323 T324 L325 D454 E472Y241-R316 PolarHBondContact O-NH1 3.49Å; Y241-R316 PolarHBondContact O-NH2 3.47Å; L242-R316 HydrophobicContact CD2-CG 4.3Å; R316-D323 HydrophobicContact CG-CB 4.04Å; R316-D323 IonicContact CZ-OD2 3.87Å; R316-D323 VanDerWaalsContact CZ-OD2 3.27Å; R316-D323 IonicContact NE-OD2 2.81Å; R316-D323 PolarHBondContact NE-OD2 3.28Å; R316-D323 IonicContact NH2-OD2 2.79Å; R316-D323 PolarHBondContact NH2-OD2 3.47Å; R316-T324 CarbonylContact C-O 3.48Å; R316-T324 WeakPolarHBondContact CA-O 3.36Å; R316-L325 HydrophobicContact CB-CD2 4.16Å; R316-D454 HydrophobicContact CB-CB 4.38Å; R316-D454 PolarHBondContact N-O 3.49Å; R316-D454 WeakPolarHBondContact O-CB 3.3Å; R316-E472 HydrophobicContact CB-CG 4.32Å; R316-E472 WeakPolarHBondContact CD-OE1 3.13Å; R316-E472 IonicContact NH1-OE1 3.53Å; R316-E472 PolarHBondContact NH1-OE1 3.24Å
317I98.3Very high96.5Very high12 Ų1238.9 Ų38.96%0.06219%0.193CC..EExtended strand (participates in β ladder)trans-111.6123.3-179.4-51.8-57.9000107.2D323 T324 Q326 E412I317-D323 CarbonylContact O-C 3.21Å; I317-D323 VanDerWaalsContact O-CA 3.26Å; I317-D323 WeakPolarHBondContact O-CA 3.34Å; I317-D323 VanDerWaalsContact O-CB 3.31Å; I317-D323 WeakPolarHBondContact O-CB 3.29Å; I317-T324 PolarHBondContact N-O 3.41Å; I317-T324 PolarHBondContact O-N 3.07Å; I317-Q326 HydrophobicContact CD1-CB 4Å; I317-Q326 HydrophobicContact CG1-CB 3.61Å; I317-E412 HydrophobicContact CD1-CB 4.42Å; I317-E412 VanDerWaalsContact CD1-CD 3.47Å; I317-E412 HydrophobicContact CD1-CG 3.94Å
318P98.3Very high96.4Very high10 Ų1039.8 Ų39.87%0.06520%0.2CC..  trans-66.5137.6-179.533.5-41.9000110.8D323 W391 A392 R395P318-D323 WeakPolarHBondContact CA-OD1 3.3Å; P318-W391 HydrophobicContact CB-CB 4.28Å; P318-W391 HydrophobicContact CB-CG 3.9Å; P318-W391 VanDerWaalsContact CG-CD1 3.45Å; P318-W391 HydrophobicContact CG-CD2 3.93Å; P318-W391 HydrophobicContact CG-CG 3.74Å; P318-W391 HydrophobicContact CG-CZ2 4.45Å; P318-A392 HydrophobicContact CB-CB 3.98Å; P318-R395 HydrophobicContact CG-CB 4.34Å
319G97.6Very high95.6Very high19 Ų1947.2 Ų47.220%0.19623%0.232CC..  trans-125165.2166.700000110.3R245 T322 D323 A392R245-G319 PolarHBondContact NH1-O 3.07Å; G319-T322 WeakPolarHBondContact CA-O 3.47Å; G319-D323 PolarHBondContact N-OD1 2.92Å; G319-A392 WeakPolarHBondContact O-CB 3.35Å
320E96.9Very high95.1Very high92 Ų9245.3 Ų45.343%0.4323%0.225SC..SBendtrans-67.6-51.9178.9-66.6-166.6-126.100110.9R245 V389 A392 K393R245-E320 WeakPolarHBondContact CD-O 3.44Å; R245-E320 PolarHBondContact NH1-O 3.12Å; E320-V389 WeakPolarHBondContact O-CG2 3.26Å; E320-A392 HydrophobicContact CG-CB 4.23Å; E320-K393 HydrophobicContact CG-CG 4.33Å; E320-K393 WeakPolarHBondContact OE2-CE 3.47Å; E320-K393 IonicContact OE2-NZ 2.77Å
321E94.1Very high95Very high165 Ų16541.4 Ų41.477%0.77121%0.212SC*.SBendtrans-92.2-40.4179.2-61.8-175.5173.500113.1R245R245-E321 PolarHBondContact NH1-O 3Å
322T95.3Very high94.9Very high42 Ų4245.8 Ų45.826%0.25823%0.231SC..  trans-144.8130.2-173.5-55.40000109.7E238 L242 R243 G319E238-T322 HydrophobicContact CG-CG2 4.3Å; L242-T322 HydrophobicContact CB-CG2 4.16Å; R243-T322 HydrophobicContact CG-CG2 3.84Å; R243-T322 WeakPolarHBondContact CG-OG1 3.12Å; G319-T322 WeakPolarHBondContact CA-O 3.47Å
323D98.3Very high94.9Very high1 Ų146.1 Ų46.11%0.00523%0.232CC..  trans-76.8165.9172.2-67.17.2000110.5L242 R245 R316 I317 P318 G319 R388L242-D323 HydrophobicContact CB-CB 4.33Å; L242-D323 HydrophobicContact CD2-CB 4.05Å; L242-D323 PolarHBondContact O-N 3.26Å; R245-D323 IonicContact CZ-OD1 2.98Å; R245-D323 IonicContact NH1-OD1 2.63Å; R245-D323 PolarHBondContact NH1-OD1 2.94Å; R245-D323 IonicContact NH2-OD1 3.55Å; R245-D323 PolarHBondContact NH2-OD1 3.28Å; R245-D323 IonicContact NH2-OD2 2.78Å; R316-D323 HydrophobicContact CG-CB 4.04Å; R316-D323 IonicContact CZ-OD2 3.87Å; R316-D323 VanDerWaalsContact CZ-OD2 3.27Å; R316-D323 IonicContact NE-OD2 2.81Å; R316-D323 PolarHBondContact NE-OD2 3.28Å; R316-D323 IonicContact NH2-OD2 2.79Å; R316-D323 PolarHBondContact NH2-OD2 3.47Å; I317-D323 CarbonylContact O-C 3.21Å; I317-D323 VanDerWaalsContact O-CA 3.26Å; I317-D323 WeakPolarHBondContact O-CA 3.34Å; I317-D323 VanDerWaalsContact O-CB 3.31Å; I317-D323 WeakPolarHBondContact O-CB 3.29Å; P318-D323 WeakPolarHBondContact CA-OD1 3.3Å; G319-D323 PolarHBondContact N-OD1 2.92Å; D323-R388 IonicContact OD2-CZ 2.71Å; D323-R388 IonicContact OD2-NE 2.85Å; D323-R388 PolarHBondContact OD2-NE 3.32Å; D323-R388 IonicContact OD2-NH2 3.99Å; D323-R388 PolarHBondContact OD2-NH2 3.43Å
324T97.3Very high95Very high80 Ų8045.9 Ų45.949%0.49123%0.231SC..EExtended strand (participates in β ladder)trans-134.1151.5176.659.10000111.8R316 I317R316-T324 CarbonylContact C-O 3.48Å; R316-T324 WeakPolarHBondContact CA-O 3.36Å; I317-T324 PolarHBondContact N-O 3.41Å; I317-T324 PolarHBondContact O-N 3.07Å
325L96.2Very high95Very high30 Ų3045.9 Ų45.916%0.15723%0.231CC..EExtended strand (participates in β ladder)trans-92.6111.5170.9-73.8170.4000110.2E237 L242 T314 R316 S474 W475E237-L325 HydrophobicContact CG-CD1 4.38Å; L242-L325 HydrophobicContact CD2-CG 4.34Å; T314-L325 HydrophobicContact CG2-CB 4.35Å; T314-L325 HydrophobicContact CG2-CD2 4.13Å; R316-L325 HydrophobicContact CB-CD2 4.16Å; L325-S474 WeakPolarHBondContact CD2-OG 3.49Å; L325-W475 HydrophobicContact CD1-CB 3.88Å; L325-W475 HydrophobicContact CD2-CB 4.48Å
326Q96.3Very high95.1Very high57 Ų5745.9 Ų45.927%0.26623%0.231SC..EExtended strand (participates in β ladder)trans-90.3114.8173-177.1-169.7102.700109.4T314 S315 I317 V328T314-Q326 CarbonylContact C-O 3.5Å; T314-Q326 WeakPolarHBondContact CA-O 3.34Å; T314-Q326 WeakPolarHBondContact CG2-O 3.24Å; S315-Q326 PolarHBondContact N-O 3.04Å; S315-Q326 PolarHBondContact O-N 3.11Å; I317-Q326 HydrophobicContact CD1-CB 4Å; I317-Q326 HydrophobicContact CG1-CB 3.61Å; Q326-V328 HydrophobicContact CG-CG1 4.42Å
327H95.6Very high95.1Very high77 Ų7746.2 Ų46.236%0.35623%0.232SC..EExtended strand (participates in β ladder)trans-111.4129173.4179.373.2000111.4E309 F312 T314E309-H327 PolarHBondContact O-CE1 3.21Å; F312-H327 PolarHBondContact O-CE1 3.47Å; F312-H327 VanDerWaalsContact O-CE1 3.24Å; F312-H327 PolarHBondContact O-ND1 2.84Å; T314-H327 HydrophobicContact CG2-CB 4.22Å; T314-H327 PolarHBondContact OG1-ND1 3.03Å
328V93.1Very high95.1Very high33 Ų3346 Ų4620%0.223%0.231CC..  trans-114139177.4-55.70000112.6N313 Q326 D330 K413N313-V328 HydrophobicContact CB-CG2 3.71Å; N313-V328 WeakPolarHBondContact CB-O 3.45Å; N313-V328 PolarHBondContact ND2-O 3.34Å; N313-V328 PolarHBondContact O-N 2.91Å; Q326-V328 HydrophobicContact CG-CG1 4.42Å; V328-D330 PolarHBondContact O-N 2.97Å; V328-K413 HydrophobicContact CG1-CG 4.24Å; V328-K413 HydrophobicContact CG2-CB 4.3Å; V328-K413 HydrophobicContact CG2-CG 4.47Å
329K80.3Confident95Very high158 Ų15850.6 Ų50.669%0.68725%0.25SS*.SBendtrans-73.7-22.9-166.1-68.5-176.51781770115.3R45R45-K329 PolarHBondContact NH1-O 2.7Å; R45-K329 PolarHBondContact NH2-O 3.48Å
330D80.4Confident95Very high71 Ų7149.7 Ų49.738%0.3824%0.241SC..  trans-150.161.6-167.6-67.8-53.6000114.3K41 R45 V328K41-D330 IonicContact NZ-OD1 3.74Å; K41-D330 PolarHBondContact NZ-OD1 3.37Å; R45-D330 IonicContact CZ-OD1 3.63Å; R45-D330 IonicContact NH1-OD1 3.88Å; R45-D330 PolarHBondContact NH1-OD1 2.99Å; R45-D330 IonicContact NH1-OD2 3.77Å; R45-D330 PolarHBondContact NH1-OD2 3.09Å; R45-D330 IonicContact NH2-OD1 3.95Å; R45-D330 PolarHBondContact NH2-OD1 3.2Å; V328-D330 PolarHBondContact O-N 2.97Å
331S92.4Very high95Very high7 Ų745.9 Ų45.95%0.04922%0.222CC..  trans-69.6137.2171.3-170.30000112.6R283 N313 H333 K413 A415R283-S331 PolarHBondContact NH1-O 3.25Å; R283-S331 PolarHBondContact NH2-O 2.93Å; N313-S331 VanDerWaalsContact OD1-CB 3.31Å; N313-S331 WeakPolarHBondContact OD1-CB 3.09Å; S331-H333 PolarHBondContact OG-O 3.44Å; S331-K413 WeakPolarHBondContact CB-O 3.47Å; S331-K413 PolarHBondContact OG-O 3.44Å; S331-A415 PolarHBondContact OG-N 2.68Å; S331-A415 VanDerWaalsContact OG-N 3.12Å
332K92.9Very high95.3Very high92 Ų9238 Ų3840%0.419%0.186SC..  trans-118.25.3-177.6-70.1-174.9179.2-175.10113.5S34 W346 L347 Y348S34-K332 PolarHBondContact OG-NZ 3.34Å; K332-W346 HydrophobicContact CB-CE3 4.01Å; K332-W346 HydrophobicContact CB-CZ3 3.8Å; K332-L347 WeakPolarHBondContact O-CB 3.4Å; K332-L347 PolarHBondContact O-N 3.16Å; K332-Y348 HydrophobicContact CB-CD2 4.32Å; K332-Y348 HydrophobicContact CG-CD2 4.48Å
333H97.9Very high95.4Very high15 Ų1536.1 Ų36.17%0.06917%0.174CC..EExtended strand (participates in β ladder)trans-139.1162-177.868.3-80.8000110.9S331 K344 V345 W346 A410 A415S331-H333 PolarHBondContact OG-O 3.44Å; H333-K344 HydrophobicContact CB-CG 4.07Å; H333-V345 CarbonylContact C-O 3.6Å; H333-V345 WeakPolarHBondContact CA-O 3.26Å; H333-V345 VanDerWaalsContact CB-O 3.25Å; H333-V345 WeakPolarHBondContact CB-O 3.39Å; H333-W346 HydrophobicContact CB-CD2 4.48Å; H333-W346 HydrophobicContact CB-CE3 4.11Å; H333-A410 PolarHBondContact NE2-O 2.85Å; H333-A415 PolarHBondContact O-N 2.75Å
334I98.8Very high95.4Very high1 Ų138.4 Ų38.41%0.00518%0.184CC..EExtended strand (participates in β ladder)trans-110.5166.2161.356.4175.6000108.8I276 V336 V345 L347 A415 F416 V418I276-I334 HydrophobicContact CD1-CD1 3.96Å; I276-I334 HydrophobicContact CG2-CD1 4.16Å; I334-V336 HydrophobicContact CD1-CG2 3.89Å; I334-V336 HydrophobicContact CG1-CG2 4.2Å; I334-V345 HydrophobicContact CD1-CB 4.43Å; I334-V345 HydrophobicContact CG1-CB 3.88Å; I334-V345 PolarHBondContact N-O 2.79Å; I334-V345 PolarHBondContact O-N 3.48Å; I334-L347 HydrophobicContact CD1-CD2 4.21Å; I334-L347 HydrophobicContact CG1-CD2 4.01Å; I334-L347 HydrophobicContact CG2-CD1 4.11Å; I334-L347 HydrophobicContact CG2-CD2 3.97Å; I334-L347 HydrophobicContact CG2-CG 4.37Å; I334-A415 HydrophobicContact CG2-CB 4.28Å; I334-F416 HydrophobicContact CG2-CD1 3.9Å; I334-F416 HydrophobicContact CG2-CD2 4.21Å; I334-F416 HydrophobicContact CG2-CE1 3.69Å; I334-F416 HydrophobicContact CG2-CE2 4.02Å; I334-F416 HydrophobicContact CG2-CG 4.16Å; I334-F416 HydrophobicContact CG2-CZ 3.77Å; I334-V418 HydrophobicContact CD1-CG2 3.86Å
335V98.9Very high95.5Very high0 Ų034.7 Ų34.70%016%0.161CC..EExtended strand (participates in β ladder)trans-112.4134.2162.41760000108.5Y342 F343 A410 I411 A414 F417 V418 L518V335-Y342 HydrophobicContact CG1-CD1 4.24Å; V335-F343 CarbonylContact C-O 3.54Å; V335-F343 VanDerWaalsContact CA-O 3.32Å; V335-F343 WeakPolarHBondContact CA-O 3.23Å; V335-A410 HydrophobicContact CG2-CB 4.45Å; V335-I411 HydrophobicContact CB-CG1 4.35Å; V335-I411 HydrophobicContact CG1-CG1 4.03Å; V335-I411 HydrophobicContact CG2-CG1 4.09Å; V335-A414 HydrophobicContact CB-CB 4.49Å; V335-A414 HydrophobicContact CG2-CB 4.15Å; V335-F417 HydrophobicContact CB-CD2 4.02Å; V335-F417 HydrophobicContact CB-CE2 4.02Å; V335-F417 HydrophobicContact CG1-CD2 4.18Å; V335-F417 HydrophobicContact CG1-CE2 3.65Å; V335-F417 HydrophobicContact CG1-CZ 4.45Å; V335-V418 PolarHBondContact O-N 2.95Å; V335-L518 HydrophobicContact CG1-CD1 4.23Å; V335-L518 HydrophobicContact CG2-CD1 4.46Å
336V98.9Very high95.5Very high0 Ų037.9 Ų37.90%017%0.171CC..EExtended strand (participates in β ladder)trans-113.3129.1179-175.10000108.4I334 Y342 F343 V345 M363 I366 V418 L420I334-V336 HydrophobicContact CD1-CG2 3.89Å; I334-V336 HydrophobicContact CG1-CG2 4.2Å; V336-Y342 CarbonylContact O-C 3.56Å; V336-Y342 WeakPolarHBondContact O-CA 3.33Å; V336-F343 PolarHBondContact N-O 3Å; V336-F343 PolarHBondContact O-N 2.83Å; V336-V345 HydrophobicContact CB-CG2 4.47Å; V336-V345 HydrophobicContact CG2-CB 4.41Å; V336-V345 HydrophobicContact CG2-CG2 3.68Å; V336-M363 HydrophobicContact CG1-SD 4.31Å; V336-M363 HydrophobicContact CG2-CE 3.98Å; V336-M363 HydrophobicContact CG2-SD 4.04Å; V336-I366 HydrophobicContact CB-CD1 3.84Å; V336-I366 HydrophobicContact CG1-CD1 3.91Å; V336-I366 HydrophobicContact CG1-CG2 4.38Å; V336-I366 HydrophobicContact CG2-CD1 4.07Å; V336-V418 CarbonylContact C-O 3.54Å; V336-V418 VanDerWaalsContact CA-O 3.3Å; V336-V418 WeakPolarHBondContact CA-O 3.27Å; V336-V418 HydrophobicContact CG1-CB 4.43Å; V336-V418 HydrophobicContact CG1-CG1 4.35Å; V336-V418 HydrophobicContact CG2-CB 4.16Å; V336-L420 HydrophobicContact CG1-CD1 3.83Å; V336-L420 HydrophobicContact CG1-CG 3.77Å
337Y98.8Very high95.4Very high8 Ų835.3 Ų35.33%0.03116%0.159CC..EExtended strand (participates in β ladder)trans-100.6134.7170.8171.4-88.7000110.3G340 R341 Y342 V418 T419 L420 D450Y337-G340 VanDerWaalsContact CE2-CA 3.44Å; Y337-G340 VanDerWaalsContact CZ-N 3.29Å; Y337-G340 WeakPolarHBondContact OH-CA 3.38Å; Y337-G340 PolarHBondContact OH-N 3.06Å; Y337-G340 VanDerWaalsContact OH-N 3.11Å; Y337-R341 VanDerWaalsContact CA-O 3.3Å; Y337-R341 WeakPolarHBondContact CA-O 3.5Å; Y337-Y342 HydrophobicContact CD2-CD1 4.23Å; Y337-Y342 AromaticContact CD2-CE1 3.81Å; Y337-Y342 HydrophobicContact CD2-CE1 3.81Å; Y337-Y342 HydrophobicContact CD2-CE2 4.14Å; Y337-Y342 AromaticContact CD2-CZ 3.74Å; Y337-Y342 HydrophobicContact CE2-CE2 4.41Å; Y337-V418 PolarHBondContact N-O 2.91Å; Y337-T419 HydrophobicContact CD1-CG2 3.78Å; Y337-T419 HydrophobicContact CE1-CG2 4.42Å; Y337-L420 PolarHBondContact O-N 2.75Å; Y337-D450 HydrophobicContact CD1-CB 4.27Å; Y337-D450 HydrophobicContact CE1-CB 3.47Å; Y337-D450 VanDerWaalsContact CE1-CB 3.47Å
338H98.6Very high95.2Very high7 Ų736 Ų363%0.03216%0.159CC..EExtended strand (participates in β ladder)trans-150.9126.6169.5-176.456.5000110.8G340 R341 I366 L420H338-G340 PolarHBondContact O-N 2.79Å; H338-R341 PolarHBondContact N-O 2.82Å; H338-R341 WeakPolarHBondContact O-CB 3.32Å; H338-R341 PolarHBondContact O-N 3.24Å; H338-R341 VanDerWaalsContact O-N 3.1Å; H338-R341 PolarHBondContact O-NE 2.85Å; H338-I366 HydrophobicContact CB-CG2 3.7Å; H338-L420 HydrophobicContact CB-CB 4.25Å; H338-L420 PolarHBondContact ND1-O 3.03Å
339K96.8Very high95Very high108 Ų10835.8 Ų35.847%0.4716%0.156SC..THydrogen-bonded Turntrans44.354.9178.1-70.6-177.6173.3-178.40113.6R341 D422K339-R341 VanDerWaalsContact C-N 3.33Å; K339-R341 PolarHBondContact O-N 2.98Å; K339-D422 VanDerWaalsContact CE-OD2 3.32Å; K339-D422 WeakPolarHBondContact CE-OD2 3.34Å; K339-D422 HydrophobicContact CG-CB 4.29Å
340G97.1Very high95.2Very high0 Ų031.8 Ų31.80%014%0.142CC..THydrogen-bonded Turntrans79.18.5175.600000115.9Y337 H338 P373 E377 Q378Y337-G340 VanDerWaalsContact CE2-CA 3.44Å; Y337-G340 VanDerWaalsContact CZ-N 3.29Å; Y337-G340 WeakPolarHBondContact OH-CA 3.38Å; Y337-G340 PolarHBondContact OH-N 3.06Å; Y337-G340 VanDerWaalsContact OH-N 3.11Å; H338-G340 PolarHBondContact O-N 2.79Å; G340-P373 WeakPolarHBondContact O-CB 2.96Å; G340-E377 CarbonylContact O-C 3.58Å; G340-E377 WeakPolarHBondContact O-CG 3.41Å; G340-Q378 WeakPolarHBondContact O-CA 3.49Å
341R98.1Very high95.3Very high11 Ų1129.5 Ų29.54%0.04214%0.135CC..EExtended strand (participates in β ladder)trans-126.5145.8-172.9-61.1162.8-61.2164.83.4111.2Y337 H338 K339 F343 D369 S371 P373 E377Y337-R341 VanDerWaalsContact CA-O 3.3Å; Y337-R341 WeakPolarHBondContact CA-O 3.5Å; H338-R341 PolarHBondContact N-O 2.82Å; H338-R341 WeakPolarHBondContact O-CB 3.32Å; H338-R341 PolarHBondContact O-N 3.24Å; H338-R341 VanDerWaalsContact O-N 3.1Å; H338-R341 PolarHBondContact O-NE 2.85Å; K339-R341 VanDerWaalsContact C-N 3.33Å; K339-R341 PolarHBondContact O-N 2.98Å; R341-F343 HydrophobicContact CB-CD2 4.48Å; R341-F343 HydrophobicContact CB-CE2 3.58Å; R341-F343 HydrophobicContact CB-CZ 3.99Å; R341-D369 PolarHBondContact NH1-O 2.94Å; R341-D369 IonicContact NH1-OD1 2.97Å; R341-D369 PolarHBondContact NH1-OD1 3.05Å; R341-D369 PolarHBondContact NH2-O 3.38Å; R341-S371 WeakPolarHBondContact CD-O 3.45Å; R341-S371 PolarHBondContact NH1-O 3.46Å; R341-P373 HydrophobicContact CG-CB 3.99Å; R341-E377 WeakPolarHBondContact CA-OE1 3.35Å
342Y98.8Very high95.1Very high0 Ų033 Ų330%015%0.147CC..EExtended strand (participates in β ladder)trans-114.7133.3-177.3-57.7-101000111.4V335 V336 Y337 E377 L380 A381 I411 F417 W452 K517 L518 W520V335-Y342 HydrophobicContact CG1-CD1 4.24Å; V336-Y342 CarbonylContact O-C 3.56Å; V336-Y342 WeakPolarHBondContact O-CA 3.33Å; Y337-Y342 HydrophobicContact CD2-CD1 4.23Å; Y337-Y342 AromaticContact CD2-CE1 3.81Å; Y337-Y342 HydrophobicContact CD2-CE1 3.81Å; Y337-Y342 HydrophobicContact CD2-CE2 4.14Å; Y337-Y342 AromaticContact CD2-CZ 3.74Å; Y337-Y342 HydrophobicContact CE2-CE2 4.41Å; Y342-E377 HydrophobicContact CD2-CG 3.84Å; Y342-E377 HydrophobicContact CE2-CG 3.95Å; Y342-E377 PolarHBondContact N-OE1 2.79Å; Y342-L380 HydrophobicContact CE2-CB 4.31Å; Y342-L380 HydrophobicContact CE2-CD2 4.26Å; Y342-A381 WeakPolarHBondContact OH-CB 3.4Å; Y342-A381 PolarHBondContact OH-N 3.1Å; Y342-I411 HydrophobicContact CD1-CD1 3.93Å; Y342-I411 HydrophobicContact CE1-CD1 4.22Å; Y342-F417 HydrophobicContact CD1-CE2 4.07Å; Y342-F417 AromaticContact CD1-CZ 3.86Å; Y342-F417 HydrophobicContact CD1-CZ 3.86Å; Y342-F417 HydrophobicContact CE1-CE2 4.23Å; Y342-F417 AromaticContact CE1-CZ 3.76Å; Y342-F417 HydrophobicContact CE1-CZ 3.76Å; Y342-W452 HydrophobicContact CE1-CE3 4.21Å; Y342-W452 HydrophobicContact CE1-CZ3 4.32Å; Y342-K517 WeakPolarHBondContact O-CA 3.47Å; Y342-L518 PolarHBondContact O-N 2.68Å; Y342-W520 HydrophobicContact CD2-CZ2 4.39Å; Y342-W520 AromaticContact CD2-NE1 3.92Å
343F98.8Very high95.2Very high3 Ų330.1 Ų30.11%0.01314%0.136CC..EExtended strand (participates in β ladder)trans-127.1126.6-178.1-59.3-96000110.6V335 V336 R341 I366 D369 P515 T516 K517V335-F343 CarbonylContact C-O 3.54Å; V335-F343 VanDerWaalsContact CA-O 3.32Å; V335-F343 WeakPolarHBondContact CA-O 3.23Å; V336-F343 PolarHBondContact N-O 3Å; V336-F343 PolarHBondContact O-N 2.83Å; R341-F343 HydrophobicContact CB-CD2 4.48Å; R341-F343 HydrophobicContact CB-CE2 3.58Å; R341-F343 HydrophobicContact CB-CZ 3.99Å; F343-I366 HydrophobicContact CB-CD1 3.85Å; F343-I366 HydrophobicContact CB-CG1 4.15Å; F343-I366 HydrophobicContact CD1-CG1 4.22Å; F343-I366 HydrophobicContact CD2-CD1 4.45Å; F343-I366 HydrophobicContact CD2-CG1 4.19Å; F343-I366 HydrophobicContact CD2-CG2 3.65Å; F343-I366 HydrophobicContact CE2-CG2 3.72Å; F343-I366 HydrophobicContact CG-CD1 4.16Å; F343-I366 HydrophobicContact CG-CG1 3.94Å; F343-I366 HydrophobicContact CG-CG2 4.27Å; F343-I366 HydrophobicContact CZ-CG2 4.37Å; F343-D369 HydrophobicContact CZ-CB 4.25Å; F343-P515 HydrophobicContact CB-CB 4.23Å; F343-P515 HydrophobicContact CD1-CB 4.3Å; F343-T516 CarbonylContact C-O 3.35Å; F343-T516 WeakPolarHBondContact CA-O 3.23Å; F343-K517 HydrophobicContact CD1-CB 3.96Å; F343-K517 HydrophobicContact CD1-CG 4.44Å; F343-K517 HydrophobicContact CE1-CB 3.84Å; F343-K517 HydrophobicContact CE1-CD 4.46Å; F343-K517 HydrophobicContact CE1-CG 4.08Å; F343-K517 HydrophobicContact CZ-CG 4.47Å
344K98.6Very high95Very high49 Ų4929.6 Ų29.621%0.21313%0.134CC..EExtended strand (participates in β ladder)trans-78.9123.6167.6-178.6176.1-179.8-179.50109.3H333 A410 T516 L518H333-K344 HydrophobicContact CB-CG 4.07Å; K344-A410 HydrophobicContact CD-CB 4.43Å; K344-T516 PolarHBondContact N-O 3.26Å; K344-T516 PolarHBondContact O-N 2.7Å; K344-L518 HydrophobicContact CB-CD2 3.93Å
345V98.6Very high95Very high2 Ų234.4 Ų34.41%0.01216%0.155CC..EExtended strand (participates in β ladder)trans-119.5117.7178.3-176.60000109.6H333 I334 V336 Q362 M363 I366 P515H333-V345 CarbonylContact C-O 3.6Å; H333-V345 WeakPolarHBondContact CA-O 3.26Å; H333-V345 VanDerWaalsContact CB-O 3.25Å; H333-V345 WeakPolarHBondContact CB-O 3.39Å; I334-V345 HydrophobicContact CD1-CB 4.43Å; I334-V345 HydrophobicContact CG1-CB 3.88Å; I334-V345 PolarHBondContact N-O 2.79Å; I334-V345 PolarHBondContact O-N 3.48Å; V336-V345 HydrophobicContact CB-CG2 4.47Å; V336-V345 HydrophobicContact CG2-CB 4.41Å; V336-V345 HydrophobicContact CG2-CG2 3.68Å; V345-Q362 HydrophobicContact CG1-CB 4.22Å; V345-Q362 HydrophobicContact CG1-CG 4.49Å; V345-M363 HydrophobicContact CG1-CE 4.11Å; V345-M363 HydrophobicContact CG2-CE 4.08Å; V345-I366 HydrophobicContact CG2-CD1 3.77Å; V345-P515 HydrophobicContact CG2-CB 4.08Å; V345-P515 HydrophobicContact CG2-CG 4.38Å
346W96.7Very high94.9Very high97 Ų9735.2 Ų35.237%0.36716%0.16SC..EExtended strand (participates in β ladder)trans-70.1139.2173.7-68.4105.3000110.8K332 H333 L354K332-W346 HydrophobicContact CB-CE3 4.01Å; K332-W346 HydrophobicContact CB-CZ3 3.8Å; H333-W346 HydrophobicContact CB-CD2 4.48Å; H333-W346 HydrophobicContact CB-CE3 4.11Å; W346-L354 WeakPolarHBondContact O-CD1 3.34Å
347L94Very high94.9Very high2 Ų237.6 Ų37.61%0.0117%0.169CC..  trans-95.5-9.7-176.1-63.8171.4000113.5I276 L280 K332 I334 L353 L354 A415I276-L347 HydrophobicContact CG2-CD2 4.42Å; L280-L347 HydrophobicContact CD1-CB 4.33Å; L280-L347 HydrophobicContact CD1-CD1 4.3Å; L280-L347 HydrophobicContact CD1-CD2 3.58Å; L280-L347 HydrophobicContact CD1-CG 4.26Å; L280-L347 HydrophobicContact CD2-CD1 3.53Å; L280-L347 HydrophobicContact CD2-CD2 4.33Å; L280-L347 HydrophobicContact CD2-CG 4.38Å; K332-L347 WeakPolarHBondContact O-CB 3.4Å; K332-L347 PolarHBondContact O-N 3.16Å; I334-L347 HydrophobicContact CD1-CD2 4.21Å; I334-L347 HydrophobicContact CG1-CD2 4.01Å; I334-L347 HydrophobicContact CG2-CD1 4.11Å; I334-L347 HydrophobicContact CG2-CD2 3.97Å; I334-L347 HydrophobicContact CG2-CG 4.37Å; L347-L353 WeakPolarHBondContact O-CD1 3.29Å; L347-L354 PolarHBondContact O-N 3.41Å; L347-A415 HydrophobicContact CD1-CB 4.21Å
348Y91.3Very high94.8Very high91 Ų9137.4 Ų37.436%0.35717%0.168SC..EExtended strand (participates in β ladder)trans-130.7141.8-172.6-60.6-93.9000110.8K332 R352 L353K332-Y348 HydrophobicContact CB-CD2 4.32Å; K332-Y348 HydrophobicContact CG-CD2 4.48Å; Y348-R352 CarbonylContact C-O 3.52Å; Y348-R352 WeakPolarHBondContact CA-O 3.12Å; Y348-R352 WeakPolarHBondContact CB-O 3.07Å; Y348-L353 HydrophobicContact CD1-CD1 4.3Å; Y348-L353 HydrophobicContact CE1-CB 4.46Å; Y348-L353 HydrophobicContact CE1-CD1 3.84Å
349H88.1Confident94.8Very high30 Ų3037.2 Ų37.214%0.13917%0.168CC..EExtended strand (participates in β ladder)trans-143.9139.5172.5179.165.6000107.9G351 R352 L354 N511H349-G351 PolarHBondContact O-N 3.32Å; H349-R352 PolarHBondContact N-O 3.02Å; H349-R352 WeakPolarHBondContact O-CG 3.34Å; H349-R352 PolarHBondContact O-N 3.05Å; H349-R352 VanDerWaalsContact O-O 3.11Å; H349-L354 HydrophobicContact CB-CD2 3.66Å; H349-N511 PolarHBondContact CE1-O 2.75Å
350D85.4Confident94.9Very high74 Ų7432.2 Ų32.240%0.39615%0.146SC..THydrogen-bonded Turntrans51.238.6-176.4-62.8-19.1000114.7Q30 R352Q30-D350 PolarHBondContact NE2-OD1 3.28Å; D350-R352 PolarHBondContact O-N 3.24Å; D350-R352 VanDerWaalsContact O-N 3.1Å
351G81.9Confident95Very high23 Ų2333.4 Ų33.424%0.23715%0.151CC..THydrogen-bonded Turntrans70.8-0.2-179.800000115.2H37 H349H37-G351 PolarHBondContact CD2-O 3.48Å; H37-G351 PolarHBondContact NE2-O 2.85Å; H349-G351 PolarHBondContact O-N 3.32Å
352R89.5Confident95Very high79 Ų7932.9 Ų32.930%0.29815%0.15SC..EExtended strand (participates in β ladder)trans-109.1161.3175.463.4166.6-178.583.8-1.7111.8Y348 H349 D350 E358Y348-R352 CarbonylContact C-O 3.52Å; Y348-R352 WeakPolarHBondContact CA-O 3.12Å; Y348-R352 WeakPolarHBondContact CB-O 3.07Å; H349-R352 PolarHBondContact N-O 3.02Å; H349-R352 WeakPolarHBondContact O-CG 3.34Å; H349-R352 PolarHBondContact O-N 3.05Å; H349-R352 VanDerWaalsContact O-O 3.11Å; D350-R352 PolarHBondContact O-N 3.24Å; D350-R352 VanDerWaalsContact O-N 3.1Å; R352-E358 IonicContact CZ-OE1 2.68Å; R352-E358 IonicContact CZ-OE2 3.22Å; R352-E358 IonicContact NH1-OE1 3.4Å; R352-E358 IonicContact NH1-OE2 3.47Å; R352-E358 PolarHBondContact NH1-OE2 2.75Å; R352-E358 VanDerWaalsContact NH2-CD 3.35Å; R352-E358 IonicContact NH2-OE1 3.69Å; R352-E358 PolarHBondContact NH2-OE1 3.07Å; R352-E358 IonicContact NH2-OE2 2.69Å; R352-E358 PolarHBondContact NH2-OE2 2.86Å
353L93.1Very high95Very high33 Ų3332.9 Ų32.917%0.17315%0.15CC..EExtended strand (participates in β ladder)trans-63.7143.4167.5-165.169.2000109.1L280 L281 L347 Y348L280-L353 HydrophobicContact CB-CD1 3.89Å; L280-L353 HydrophobicContact CB-CD2 3.71Å; L280-L353 HydrophobicContact CB-CG 4.38Å; L280-L353 HydrophobicContact CD1-CD1 3.73Å; L280-L353 HydrophobicContact CD1-CD2 4.46Å; L280-L353 HydrophobicContact CD1-CG 4.36Å; L280-L353 HydrophobicContact CG-CD1 4.25Å; L281-L353 HydrophobicContact CD2-CD2 4.48Å; L347-L353 WeakPolarHBondContact O-CD1 3.29Å; Y348-L353 HydrophobicContact CD1-CD1 4.3Å; Y348-L353 HydrophobicContact CE1-CB 4.46Å; Y348-L353 HydrophobicContact CE1-CD1 3.84Å
354L95.6Very high95Very high3 Ų336.1 Ų36.12%0.01617%0.165CC..PPolyproline II helixtrans-59.9138167.7-68.3-178.2000110H277 W346 L347 H349 E358 I359 I512H277-L354 PolarHBondContact CE1-O 3.31Å; H277-L354 PolarHBondContact ND1-O 3.25Å; W346-L354 WeakPolarHBondContact O-CD1 3.34Å; L347-L354 PolarHBondContact O-N 3.41Å; H349-L354 HydrophobicContact CB-CD2 3.66Å; L354-E358 HydrophobicContact CB-CB 4.37Å; L354-E358 HydrophobicContact CD2-CB 4.33Å; L354-I359 HydrophobicContact CB-CD1 4.14Å; L354-I359 HydrophobicContact CB-CG1 3.58Å; L354-I359 HydrophobicContact CD1-CG1 4.31Å; L354-I512 HydrophobicContact CD2-CB 4.33Å; L354-I512 HydrophobicContact CD2-CG2 3.9Å
355K96.8Very high94.9Very high103 Ų10336.9 Ų36.945%0.44817%0.166SC..PPolyproline II helixtrans-73.8158.6175-67.1173.9-177.5179.90109.9R357 E358 I359K355-R357 PolarHBondContact O-N 2.82Å; K355-E358 HydrophobicContact CB-CG 4.27Å; K355-E358 WeakPolarHBondContact CB-OE2 3.41Å; K355-E358 PolarHBondContact N-OE2 3.29Å; K355-E358 WeakPolarHBondContact O-CB 3.41Å; K355-E358 PolarHBondContact O-N 2.89Å; K355-I359 WeakPolarHBondContact O-CG1 3.48Å; K355-I359 PolarHBondContact O-N 3.22Å
356P97.9Very high94.9Very high17 Ų1736.8 Ų36.811%0.1117%0.166CC..Hα-helixtrans-51.4-48.4179.5-29.135.9000114.5N274 H277 E358 I359 E360 L496 C504N274-P356 WeakPolarHBondContact OD1-CB 3.24Å; N274-P356 WeakPolarHBondContact OD1-CG 3.3Å; H277-P356 HydrophobicContact CB-CB 4.48Å; H277-P356 HydrophobicContact CB-CG 3.92Å; P356-E358 VanDerWaalsContact C-N 3.28Å; P356-E358 PolarHBondContact O-N 3.12Å; P356-I359 PolarHBondContact O-N 2.68Å; P356-I359 VanDerWaalsContact O-N 3.1Å; P356-E360 WeakPolarHBondContact O-CB 3.44Å; P356-E360 PolarHBondContact O-N 2.85Å; P356-L496 HydrophobicContact CG-CD1 4.49Å; P356-L496 HydrophobicContact CG-CD2 4.46Å; P356-C504 HydrophobicContact CB-CB 3.78Å
357R97.8Very high95Very high49 Ų4933.9 Ų33.919%0.18516%0.157CC..Hα-helixtrans-61.6-31.8177.7-171.459.4161.4164.1-3.8114K355 E360 Q361 H503 C504 G506 T508K355-R357 PolarHBondContact O-N 2.82Å; R357-E360 WeakPolarHBondContact CD-OE2 3.42Å; R357-E360 IonicContact CZ-OE2 2.74Å; R357-E360 IonicContact NE-OE2 2.79Å; R357-E360 IonicContact NH1-OE1 2.9Å; R357-E360 PolarHBondContact NH1-OE1 2.74Å; R357-E360 IonicContact NH1-OE2 3.38Å; R357-E360 PolarHBondContact NH1-OE2 3.23Å; R357-Q361 WeakPolarHBondContact O-CB 3.48Å; R357-Q361 PolarHBondContact O-N 3.13Å; R357-H503 PolarHBondContact NH1-ND1 2.8Å; R357-C504 HydrophobicContact CB-CB 4.24Å; R357-C504 WeakPolarHBondContact CD-O 3.34Å; R357-G506 WeakPolarHBondContact CG-O 3.47Å; R357-T508 HydrophobicContact CG-CG2 4Å
358E97.9Very high95.2Very high4 Ų439 Ų392%0.01918%0.184CC..Hα-helixtrans-74.3-37.3175-63.2174.1134.900111.4R352 L354 K355 P356 Q361 Q362 N509 I512R352-E358 IonicContact CZ-OE1 2.68Å; R352-E358 IonicContact CZ-OE2 3.22Å; R352-E358 IonicContact NH1-OE1 3.4Å; R352-E358 IonicContact NH1-OE2 3.47Å; R352-E358 PolarHBondContact NH1-OE2 2.75Å; R352-E358 VanDerWaalsContact NH2-CD 3.35Å; R352-E358 IonicContact NH2-OE1 3.69Å; R352-E358 PolarHBondContact NH2-OE1 3.07Å; R352-E358 IonicContact NH2-OE2 2.69Å; R352-E358 PolarHBondContact NH2-OE2 2.86Å; L354-E358 HydrophobicContact CB-CB 4.37Å; L354-E358 HydrophobicContact CD2-CB 4.33Å; K355-E358 HydrophobicContact CB-CG 4.27Å; K355-E358 WeakPolarHBondContact CB-OE2 3.41Å; K355-E358 PolarHBondContact N-OE2 3.29Å; K355-E358 WeakPolarHBondContact O-CB 3.41Å; K355-E358 PolarHBondContact O-N 2.89Å; P356-E358 VanDerWaalsContact C-N 3.28Å; P356-E358 PolarHBondContact O-N 3.12Å; E358-Q361 WeakPolarHBondContact O-CB 3.35Å; E358-Q361 PolarHBondContact O-N 3.16Å; E358-Q362 VanDerWaalsContact O-CG 3.24Å; E358-Q362 WeakPolarHBondContact O-CG 3.45Å; E358-Q362 PolarHBondContact O-N 2.88Å; E358-N509 HydrophobicContact CG-CB 4.03Å; E358-N509 WeakPolarHBondContact OE1-CB 3.34Å; E358-N509 PolarHBondContact OE1-ND2 2.75Å; E358-I512 HydrophobicContact CB-CD1 3.93Å; E358-I512 HydrophobicContact CG-CG2 4.42Å
359I98.5Very high95.5Very high3 Ų337.1 Ų37.12%0.01518%0.181CC..Hα-helixtrans-68.3-43.7175.3-60.4170.3000109.7I276 H277 L280 L354 K355 P356 Q361 Q362 M363I276-I359 HydrophobicContact CB-CG2 4.06Å; I276-I359 HydrophobicContact CD1-CG2 4.04Å; I276-I359 HydrophobicContact CG2-CD1 4.1Å; I276-I359 HydrophobicContact CG2-CG2 3.92Å; H277-I359 HydrophobicContact CB-CD1 3.95Å; L280-I359 HydrophobicContact CD1-CD1 4.42Å; L354-I359 HydrophobicContact CB-CD1 4.14Å; L354-I359 HydrophobicContact CB-CG1 3.58Å; L354-I359 HydrophobicContact CD1-CG1 4.31Å; K355-I359 WeakPolarHBondContact O-CG1 3.48Å; K355-I359 PolarHBondContact O-N 3.22Å; P356-I359 PolarHBondContact O-N 2.68Å; P356-I359 VanDerWaalsContact O-N 3.1Å; I359-Q361 VanDerWaalsContact C-N 3.31Å; I359-Q361 PolarHBondContact O-N 3.45Å; I359-Q362 WeakPolarHBondContact O-CA 3.48Å; I359-Q362 WeakPolarHBondContact O-CB 3.21Å; I359-Q362 PolarHBondContact O-N 3.5Å; I359-M363 HydrophobicContact CG2-CE 4.46Å; I359-M363 HydrophobicContact CG2-CG 4.45Å; I359-M363 WeakPolarHBondContact O-CG 3.42Å; I359-M363 PolarHBondContact O-N 3.35Å
360E98.6Very high95.9Very high4 Ų440 Ų402%0.01921%0.209CC..Hα-helixtrans-53.4-48.4172.1169.9176.9-162.700111.3A269 A270 P356 R357 Q362 M363 Q364 H503 C504A269-E360 HydrophobicContact CB-CG 4.07Å; A270-E360 VanDerWaalsContact CA-CD 3.48Å; A270-E360 WeakPolarHBondContact CA-OE1 3.22Å; A270-E360 HydrophobicContact CB-CG 4.44Å; A270-E360 VanDerWaalsContact CB-OE1 3.23Å; A270-E360 WeakPolarHBondContact CB-OE1 3.36Å; P356-E360 WeakPolarHBondContact O-CB 3.44Å; P356-E360 PolarHBondContact O-N 2.85Å; R357-E360 WeakPolarHBondContact CD-OE2 3.42Å; R357-E360 IonicContact CZ-OE2 2.74Å; R357-E360 IonicContact NE-OE2 2.79Å; R357-E360 IonicContact NH1-OE1 2.9Å; R357-E360 PolarHBondContact NH1-OE1 2.74Å; R357-E360 IonicContact NH1-OE2 3.38Å; R357-E360 PolarHBondContact NH1-OE2 3.23Å; E360-Q362 PolarHBondContact O-N 2.79Å; E360-M363 PolarHBondContact O-N 3.02Å; E360-Q364 PolarHBondContact O-N 3.22Å; E360-H503 IonicContact OE1-CE1 3.22Å; E360-H503 IonicContact OE1-CG 3.54Å; E360-H503 IonicContact OE1-ND1 3.93Å; E360-H503 PolarHBondContact OE1-ND1 2.81Å; E360-C504 VanDerWaalsContact OE2-CB 3.25Å; E360-C504 WeakPolarHBondContact OE2-CB 3.41Å; E360-C504 PolarHBondContact OE2-N 3.3Å
361Q98.3Very high96.4Very high24 Ų2438.5 Ų38.511%0.11221%0.205CC..Hα-helixtrans-55.5-38.6176-177.6-179.98.600112.1R357 E358 I359 R365 N509R357-Q361 WeakPolarHBondContact O-CB 3.48Å; R357-Q361 PolarHBondContact O-N 3.13Å; E358-Q361 WeakPolarHBondContact O-CB 3.35Å; E358-Q361 PolarHBondContact O-N 3.16Å; I359-Q361 VanDerWaalsContact C-N 3.31Å; I359-Q361 PolarHBondContact O-N 3.45Å; Q361-R365 VanDerWaalsContact NE2-NH2 3.19Å; Q361-R365 VanDerWaalsContact O-CG 3.27Å; Q361-R365 WeakPolarHBondContact O-CG 3.24Å; Q361-R365 PolarHBondContact O-N 3.34Å; Q361-N509 VanDerWaalsContact OE1-N 3.15Å; Q361-N509 PolarHBondContact OE1-O 3.28Å
362Q98.4Very high97.1Very high1 Ų144.7 Ų44.71%0.00523%0.228CC..Hα-helixtrans-69.7-38.8176.7-63.2-75.393.500112.4V345 E358 I359 E360 I366 I512 P513 P515V345-Q362 HydrophobicContact CG1-CB 4.22Å; V345-Q362 HydrophobicContact CG1-CG 4.49Å; E358-Q362 VanDerWaalsContact O-CG 3.24Å; E358-Q362 WeakPolarHBondContact O-CG 3.45Å; E358-Q362 PolarHBondContact O-N 2.88Å; I359-Q362 WeakPolarHBondContact O-CA 3.48Å; I359-Q362 WeakPolarHBondContact O-CB 3.21Å; I359-Q362 PolarHBondContact O-N 3.5Å; E360-Q362 PolarHBondContact O-N 2.79Å; Q362-I366 WeakPolarHBondContact O-CG1 3.48Å; Q362-I366 PolarHBondContact O-N 3.41Å; Q362-I512 HydrophobicContact CG-CD1 3.87Å; Q362-P513 PolarHBondContact NE2-O 2.9Å; Q362-P513 PolarHBondContact OE1-O 3.1Å; Q362-P515 HydrophobicContact CB-CG 4.21Å
363M98.8Very high97.4Very high0 Ų042.4 Ų42.40%022%0.223CC..Hα-helixtrans-67.9-41.5176.3-59.8-54.79500110.5A269 A272 I276 V336 V345 I359 E360 R365 I366 L367 L420A269-M363 HydrophobicContact CB-CB 4.05Å; A272-M363 HydrophobicContact CB-CB 4.37Å; A272-M363 HydrophobicContact CB-CG 3.75Å; A272-M363 HydrophobicContact CB-SD 4.46Å; I276-M363 HydrophobicContact CD1-CG 4.43Å; I276-M363 HydrophobicContact CD1-SD 3.86Å; V336-M363 HydrophobicContact CG1-SD 4.31Å; V336-M363 HydrophobicContact CG2-CE 3.98Å; V336-M363 HydrophobicContact CG2-SD 4.04Å; V345-M363 HydrophobicContact CG1-CE 4.11Å; V345-M363 HydrophobicContact CG2-CE 4.08Å; I359-M363 HydrophobicContact CG2-CE 4.46Å; I359-M363 HydrophobicContact CG2-CG 4.45Å; I359-M363 WeakPolarHBondContact O-CG 3.42Å; I359-M363 PolarHBondContact O-N 3.35Å; E360-M363 PolarHBondContact O-N 3.02Å; M363-R365 PolarHBondContact O-N 3.49Å; M363-I366 HydrophobicContact CE-CD1 4.04Å; M363-I366 WeakPolarHBondContact O-CB 3.37Å; M363-I366 PolarHBondContact O-N 2.96Å; M363-L367 WeakPolarHBondContact O-CG 3.01Å; M363-L367 PolarHBondContact O-N 3.1Å; M363-L420 HydrophobicContact CB-CD1 4.1Å; M363-L420 HydrophobicContact SD-CD1 4.13Å; M363-L420 HydrophobicContact SD-CD2 4.46Å
364Q98.5Very high97.7Very high71 Ų7143.3 Ų43.333%0.33223%0.227SC..Hα-helixtrans-61.3-43.4176-167.660.452.600111.4A269 E360 I366 L367 D368A269-Q364 HydrophobicContact CB-CB 4.06Å; E360-Q364 PolarHBondContact O-N 3.22Å; Q364-I366 PolarHBondContact O-N 2.86Å; Q364-L367 PolarHBondContact O-N 2.71Å; Q364-L367 VanDerWaalsContact O-N 3.11Å; Q364-D368 WeakPolarHBondContact CG-OD2 2.92Å; Q364-D368 PolarHBondContact NE2-OD1 3.16Å; Q364-D368 PolarHBondContact NE2-OD2 3.38Å; Q364-D368 WeakPolarHBondContact O-CB 3.28Å; Q364-D368 PolarHBondContact O-N 3.29Å
365R98.3Very high97.7Very high64 Ų6446.4 Ų46.424%0.24225%0.253CS..Hα-helixtrans-55.7-33.8172.4-75.2168176.6176.7-5.9113.1Q361 M363 D369 P515Q361-R365 VanDerWaalsContact NE2-NH2 3.19Å; Q361-R365 VanDerWaalsContact O-CG 3.27Å; Q361-R365 WeakPolarHBondContact O-CG 3.24Å; Q361-R365 PolarHBondContact O-N 3.34Å; M363-R365 PolarHBondContact O-N 3.49Å; R365-D369 PolarHBondContact O-N 3.02Å; R365-P515 HydrophobicContact CB-CG 4.36Å
366I98.8Very high97.7Very high1 Ų142.3 Ų42.31%0.00524%0.24CC..Hα-helixtrans-76.9-40.1177.2-67.7166.3000111.3V336 H338 F343 V345 Q362 M363 Q364 D368 D369 L420 P515V336-I366 HydrophobicContact CB-CD1 3.84Å; V336-I366 HydrophobicContact CG1-CD1 3.91Å; V336-I366 HydrophobicContact CG1-CG2 4.38Å; V336-I366 HydrophobicContact CG2-CD1 4.07Å; H338-I366 HydrophobicContact CB-CG2 3.7Å; F343-I366 HydrophobicContact CB-CD1 3.85Å; F343-I366 HydrophobicContact CB-CG1 4.15Å; F343-I366 HydrophobicContact CD1-CG1 4.22Å; F343-I366 HydrophobicContact CD2-CD1 4.45Å; F343-I366 HydrophobicContact CD2-CG1 4.19Å; F343-I366 HydrophobicContact CD2-CG2 3.65Å; F343-I366 HydrophobicContact CE2-CG2 3.72Å; F343-I366 HydrophobicContact CG-CD1 4.16Å; F343-I366 HydrophobicContact CG-CG1 3.94Å; F343-I366 HydrophobicContact CG-CG2 4.27Å; F343-I366 HydrophobicContact CZ-CG2 4.37Å; V345-I366 HydrophobicContact CG2-CD1 3.77Å; Q362-I366 WeakPolarHBondContact O-CG1 3.48Å; Q362-I366 PolarHBondContact O-N 3.41Å; M363-I366 HydrophobicContact CE-CD1 4.04Å; M363-I366 WeakPolarHBondContact O-CB 3.37Å; M363-I366 PolarHBondContact O-N 2.96Å; Q364-I366 PolarHBondContact O-N 2.86Å; I366-D368 VanDerWaalsContact C-N 3.32Å; I366-D369 WeakPolarHBondContact O-CB 3.28Å; I366-D369 PolarHBondContact O-N 2.97Å; I366-L420 HydrophobicContact CB-CD1 4.46Å; I366-L420 HydrophobicContact CG2-CD1 4.21Å; I366-P515 HydrophobicContact CD1-CB 3.97Å; I366-P515 HydrophobicContact CD1-CG 4.05Å; I366-P515 HydrophobicContact CG1-CB 3.83Å; I366-P515 HydrophobicContact CG1-CG 3.85Å
367L98.7Very high97.7Very high35 Ų3541.5 Ų41.518%0.18324%0.235CC..Hα-helixtrans-64.8-38.3176.5-67.2174.8000111.8Q268 A269 M363 Q364 D369 L420Q268-L367 HydrophobicContact CB-CD1 4.37Å; Q268-L367 HydrophobicContact CG-CD1 4.39Å; Q268-L367 VanDerWaalsContact OE1-CD2 3.28Å; A269-L367 HydrophobicContact CB-CD1 3.98Å; M363-L367 WeakPolarHBondContact O-CG 3.01Å; M363-L367 PolarHBondContact O-N 3.1Å; Q364-L367 PolarHBondContact O-N 2.71Å; Q364-L367 VanDerWaalsContact O-N 3.11Å; L367-D369 VanDerWaalsContact C-N 3.32Å; L367-L420 HydrophobicContact CD2-CB 4Å; L367-L420 HydrophobicContact CD2-CD1 3.93Å; L367-L420 HydrophobicContact CG-CD1 4.06Å
368D98.1Very high97.7Very high109 Ų10943.7 Ų43.758%0.58325%0.247SC*.SBendtrans-80.9-11.4179.8-62.3-20000113Q364 I366 A370Q364-D368 WeakPolarHBondContact CG-OD2 2.92Å; Q364-D368 PolarHBondContact NE2-OD1 3.16Å; Q364-D368 PolarHBondContact NE2-OD2 3.38Å; Q364-D368 WeakPolarHBondContact O-CB 3.28Å; Q364-D368 PolarHBondContact O-N 3.29Å; I366-D368 VanDerWaalsContact C-N 3.32Å; D368-A370 PolarHBondContact O-N 3.14Å
369D97.5Very high97.7Very high52 Ų5246.2 Ų46.228%0.27826%0.258SS..  trans-66121.7178.3-170.5-60000109.5R341 F343 R365 I366 L367 S371R341-D369 PolarHBondContact NH1-O 2.94Å; R341-D369 IonicContact NH1-OD1 2.97Å; R341-D369 PolarHBondContact NH1-OD1 3.05Å; R341-D369 PolarHBondContact NH2-O 3.38Å; F343-D369 HydrophobicContact CZ-CB 4.25Å; R365-D369 PolarHBondContact O-N 3.02Å; I366-D369 WeakPolarHBondContact O-CB 3.28Å; I366-D369 PolarHBondContact O-N 2.97Å; L367-D369 VanDerWaalsContact C-N 3.32Å; D369-S371 WeakPolarHBondContact OD1-CA 3.24Å; D369-S371 WeakPolarHBondContact OD1-CB 3.31Å; D369-S371 PolarHBondContact OD1-N 2.98Å; D369-S371 PolarHBondContact OD1-OG 3.03Å
370A95.8Very high97.7Very high90 Ų9046.1 Ų46.174%0.74426%0.257SS*.  trans-1029.5-178.900000113.6D368D368-A370 PolarHBondContact O-N 3.14Å
371S96Very high97.7Very high43 Ų4345.9 Ų45.930%0.30126%0.256SS..PPolyproline II helixtrans-68.7142178.168.60000111.5R341 D369 K517R341-S371 WeakPolarHBondContact CD-O 3.45Å; R341-S371 PolarHBondContact NH1-O 3.46Å; D369-S371 WeakPolarHBondContact OD1-CA 3.24Å; D369-S371 WeakPolarHBondContact OD1-CB 3.31Å; D369-S371 PolarHBondContact OD1-N 2.98Å; D369-S371 PolarHBondContact OD1-OG 3.03Å; S371-K517 PolarHBondContact OG-NZ 2.78Å
372E96.2Very high97.7Very high153 Ų15344.8 Ų44.872%0.71525%0.251SS*.PPolyproline II helixtrans-75150.6175.9-66.2-57.6137.800112K517E372-K517 PolarHBondContact O-NZ 3.24Å
373P97.1Very high97.7Very high32 Ų3244.8 Ų44.821%0.20825%0.251CS..PPolyproline II helixtrans-61.9147.1169.628-33.7000111.1G340 R341 E377 Q378G340-P373 WeakPolarHBondContact O-CB 2.96Å; R341-P373 HydrophobicContact CG-CB 3.99Å; P373-E377 WeakPolarHBondContact CA-OE2 3.48Å; P373-E377 HydrophobicContact CB-CB 4.21Å; P373-Q378 HydrophobicContact CB-CB 4.14Å; P373-Q378 HydrophobicContact CG-CB 4.08Å
374Q97.3Very high97.7Very high52 Ų5244.8 Ų44.824%0.24325%0.251CS..PPolyproline II helixtrans-68.1160.4172.1-66.6171.363.400110.2G376 E377 L518 Q519 W520Q374-G376 PolarHBondContact O-N 3.08Å; Q374-E377 HydrophobicContact CB-CB 4.09Å; Q374-E377 PolarHBondContact N-OE2 3.11Å; Q374-E377 WeakPolarHBondContact O-CB 3.48Å; Q374-E377 PolarHBondContact O-N 2.8Å; Q374-L518 PolarHBondContact NE2-O 3.04Å; Q374-Q519 VanDerWaalsContact NE2-OE1 3.09Å; Q374-W520 PolarHBondContact OE1-O 2.87Å
375A97.1Very high97.7Very high68 Ų6841.4 Ų41.456%0.56224%0.235SC*.THydrogen-bonded Turntrans-54.3129.117800000110.8E377A375-E377 PolarHBondContact O-N 2.9Å; A375-E377 VanDerWaalsContact O-N 3.16Å
376G96.5Very high97.6Very high17 Ų1738.3 Ų38.318%0.17522%0.223CC..THydrogen-bonded Turntrans74-15-173.900000116.5Q374 Q378 L380Q374-G376 PolarHBondContact O-N 3.08Å; G376-Q378 PolarHBondContact O-N 3.09Å; G376-L380 PolarHBondContact O-N 2.8Å
377E98Very high97.6Very high0 Ų041.1 Ų41.10%024%0.238CC..THydrogen-bonded Turntrans-63.5-43.2-175.2-173.1-175.5-17300111.7G340 R341 Y342 P373 Q374 A375 K379 L380 W520G340-E377 CarbonylContact O-C 3.58Å; G340-E377 WeakPolarHBondContact O-CG 3.41Å; R341-E377 WeakPolarHBondContact CA-OE1 3.35Å; Y342-E377 HydrophobicContact CD2-CG 3.84Å; Y342-E377 HydrophobicContact CE2-CG 3.95Å; Y342-E377 PolarHBondContact N-OE1 2.79Å; P373-E377 WeakPolarHBondContact CA-OE2 3.48Å; P373-E377 HydrophobicContact CB-CB 4.21Å; Q374-E377 HydrophobicContact CB-CB 4.09Å; Q374-E377 PolarHBondContact N-OE2 3.11Å; Q374-E377 WeakPolarHBondContact O-CB 3.48Å; Q374-E377 PolarHBondContact O-N 2.8Å; A375-E377 PolarHBondContact O-N 2.9Å; A375-E377 VanDerWaalsContact O-N 3.16Å; E377-K379 PolarHBondContact O-N 3.03Å; E377-K379 VanDerWaalsContact O-N 3.13Å; E377-L380 WeakPolarHBondContact O-CB 3.35Å; E377-L380 PolarHBondContact O-N 3.45Å; E377-L380 VanDerWaalsContact O-N 3.07Å; E377-W520 VanDerWaalsContact CD-CD1 3.47Å; E377-W520 VanDerWaalsContact CG-CD1 3.48Å; E377-W520 HydrophobicContact CG-CG 4.39Å; E377-W520 PolarHBondContact OE1-NE1 3.32Å
378Q97.6Very high97.5Very high94 Ų9439.4 Ų39.444%0.43923%0.23SC..THydrogen-bonded Turntrans-54.5-40-172.5-177.3179.711.600113.3G340 P373 G376 Y449G340-Q378 WeakPolarHBondContact O-CA 3.49Å; P373-Q378 HydrophobicContact CB-CB 4.14Å; P373-Q378 HydrophobicContact CG-CB 4.08Å; G376-Q378 PolarHBondContact O-N 3.09Å; Q378-Y449 VanDerWaalsContact O-CD2 3.24Å; Q378-Y449 WeakPolarHBondContact O-CD2 3.35Å
379K98.2Very high97.6Very high58 Ų5836.1 Ų36.125%0.25221%0.213SC..THydrogen-bonded Turntrans-104.95.6-175.6-67.3170.2174.6-176.50112.9E377 A381 A382 Y449 I530 E531 L534E377-K379 PolarHBondContact O-N 3.03Å; E377-K379 VanDerWaalsContact O-N 3.13Å; K379-A381 VanDerWaalsContact C-N 3.25Å; K379-A381 PolarHBondContact O-N 2.84Å; K379-A381 VanDerWaalsContact O-N 3.1Å; K379-A382 WeakPolarHBondContact O-CB 3.41Å; K379-A382 PolarHBondContact O-N 2.91Å; K379-Y449 HydrophobicContact CB-CG 4.48Å; K379-Y449 HydrophobicContact CG-CD1 4.3Å; K379-Y449 HydrophobicContact CG-CG 4.27Å; K379-I530 HydrophobicContact CB-CG2 3.6Å; K379-I530 VanDerWaalsContact O-CG2 3.24Å; K379-I530 WeakPolarHBondContact O-CG2 3.43Å; K379-E531 WeakPolarHBondContact CD-OE1 3.48Å; K379-E531 WeakPolarHBondContact CE-OE1 3.4Å; K379-E531 IonicContact NZ-OE1 2.84Å; K379-E531 PolarHBondContact NZ-OE1 3.12Å; K379-E531 IonicContact NZ-OE2 3.23Å; K379-E531 PolarHBondContact NZ-OE2 2.83Å; K379-L534 HydrophobicContact CD-CD2 3.65Å; K379-L534 HydrophobicContact CG-CD2 4.06Å
380L98.5Very high97.6Very high0 Ų035.9 Ų35.90%022%0.215CC..THydrogen-bonded Turntrans-52-40.8-170.8174.361.6000113.4Y342 G376 E377 A382 L383 F399 W520 I522 I530Y342-L380 HydrophobicContact CE2-CB 4.31Å; Y342-L380 HydrophobicContact CE2-CD2 4.26Å; G376-L380 PolarHBondContact O-N 2.8Å; E377-L380 WeakPolarHBondContact O-CB 3.35Å; E377-L380 PolarHBondContact O-N 3.45Å; E377-L380 VanDerWaalsContact O-N 3.07Å; L380-A382 PolarHBondContact O-N 2.78Å; L380-A382 VanDerWaalsContact O-N 3.13Å; L380-L383 HydrophobicContact CD1-CD1 3.88Å; L380-L383 PolarHBondContact O-N 3.29Å; L380-F399 HydrophobicContact CD1-CE1 3.75Å; L380-F399 HydrophobicContact CD1-CE2 4.46Å; L380-F399 HydrophobicContact CD1-CZ 3.4Å; L380-F399 HydrophobicContact CD2-CE1 4.43Å; L380-W520 HydrophobicContact CD2-CD2 3.89Å; L380-W520 HydrophobicContact CD2-CE3 3.91Å; L380-W520 HydrophobicContact CD2-CH2 3.54Å; L380-W520 HydrophobicContact CD2-CZ2 3.5Å; L380-W520 VanDerWaalsContact CD2-CZ2 3.5Å; L380-W520 HydrophobicContact CD2-CZ3 3.76Å; L380-I522 HydrophobicContact CD1-CD1 4.1Å; L380-I522 HydrophobicContact CD2-CD1 4.36Å; L380-I530 HydrophobicContact CD1-CD1 4Å
381A98.1Very high97.7Very high0 Ų031.7 Ų31.70%018%0.179CC..THydrogen-bonded Turntrans-67.8-11.5-178.100000114.1Y342 K379 L383 T384 A385 Y449 R451 W452Y342-A381 WeakPolarHBondContact OH-CB 3.4Å; Y342-A381 PolarHBondContact OH-N 3.1Å; K379-A381 VanDerWaalsContact C-N 3.25Å; K379-A381 PolarHBondContact O-N 2.84Å; K379-A381 VanDerWaalsContact O-N 3.1Å; A381-L383 PolarHBondContact O-N 3.48Å; A381-T384 WeakPolarHBondContact O-CB 3.31Å; A381-T384 PolarHBondContact O-N 2.95Å; A381-T384 PolarHBondContact O-OG1 3.33Å; A381-A385 PolarHBondContact O-N 2.9Å; A381-Y449 WeakPolarHBondContact CB-O 3.22Å; A381-R451 WeakPolarHBondContact CB-O 3.36Å; A381-W452 HydrophobicContact CB-CE3 3.93Å; A381-W452 HydrophobicContact CB-CZ3 4.21Å
382A98.6Very high97.8Very high0 Ų030 Ų300%017%0.168CC..Hα-helixtrans-56.9-28.5172.900000112.5K379 L380 T384 A385 G386 C448 I530 S533 L534K379-A382 WeakPolarHBondContact O-CB 3.41Å; K379-A382 PolarHBondContact O-N 2.91Å; L380-A382 PolarHBondContact O-N 2.78Å; L380-A382 VanDerWaalsContact O-N 3.13Å; A382-T384 PolarHBondContact O-N 3.22Å; A382-A385 WeakPolarHBondContact O-CB 3.42Å; A382-A385 PolarHBondContact O-N 2.8Å; A382-G386 PolarHBondContact O-N 2.84Å; A382-C448 WeakPolarHBondContact CA-O 3.46Å; A382-I530 HydrophobicContact CB-CG2 4.39Å; A382-S533 WeakPolarHBondContact O-CB 3.22Å; A382-L534 HydrophobicContact CB-CB 3.75Å; A382-L534 HydrophobicContact CB-CD1 4.23Å
383L98.8Very high98Very high1 Ų127.9 Ų27.91%0.00516%0.157CC..Hα-helixtrans-57.9-35171.8-64.8173.9000112.1L380 A381 A385 W391 A394 F399 V529 I530L380-L383 HydrophobicContact CD1-CD1 3.88Å; L380-L383 PolarHBondContact O-N 3.29Å; A381-L383 PolarHBondContact O-N 3.48Å; L383-A385 VanDerWaalsContact C-N 3.33Å; L383-W391 HydrophobicContact CB-CD2 3.77Å; L383-W391 HydrophobicContact CB-CE3 3.48Å; L383-W391 VanDerWaalsContact CB-CE3 3.48Å; L383-W391 HydrophobicContact CB-CG 4.27Å; L383-W391 HydrophobicContact CB-CZ3 3.96Å; L383-W391 HydrophobicContact CD1-CE3 3.73Å; L383-W391 HydrophobicContact CD1-CH2 4.43Å; L383-W391 HydrophobicContact CD1-CZ3 3.52Å; L383-W391 HydrophobicContact CD2-CE3 4.43Å; L383-W391 HydrophobicContact CG-CE3 4.07Å; L383-W391 HydrophobicContact CG-CZ3 4.32Å; L383-W391 VanDerWaalsContact O-CB 3.24Å; L383-W391 WeakPolarHBondContact O-CB 3.47Å; L383-W391 VanDerWaalsContact O-CG 3.22Å; L383-A394 HydrophobicContact CD1-CB 4.48Å; L383-A394 HydrophobicContact CD2-CB 4.26Å; L383-F399 HydrophobicContact CD1-CE2 3.99Å; L383-F399 HydrophobicContact CD1-CZ 4.2Å; L383-V529 HydrophobicContact CD2-CB 4.5Å; L383-V529 HydrophobicContact CD2-CG1 3.84Å; L383-I530 HydrophobicContact CD1-CD1 4.42Å; L383-I530 HydrophobicContact CD1-CG1 3.79Å; L383-I530 HydrophobicContact CD2-CG1 3.93Å; L383-I530 HydrophobicContact CG-CG1 3.74Å
384T98.6Very high98Very high0 Ų026.5 Ų26.50%015%0.148CC..Hα-helixtrans-79.2-19.5177.673.10000113A381 A382 R388 W391 W452 F453A381-T384 WeakPolarHBondContact O-CB 3.31Å; A381-T384 PolarHBondContact O-N 2.95Å; A381-T384 PolarHBondContact O-OG1 3.33Å; A382-T384 PolarHBondContact O-N 3.22Å; T384-R388 PolarHBondContact O-NH1 2.83Å; T384-W391 HydrophobicContact CG2-CZ2 4.25Å; T384-W452 HydrophobicContact CG2-CD2 3.89Å; T384-W452 HydrophobicContact CG2-CE3 4.19Å; T384-W452 HydrophobicContact CG2-CG 4.46Å; T384-W452 HydrophobicContact CG2-CH2 4.07Å; T384-W452 HydrophobicContact CG2-CZ2 3.74Å; T384-W452 HydrophobicContact CG2-CZ3 4.28Å; T384-F453 WeakPolarHBondContact OG1-CD2 3.39Å; T384-F453 PolarHBondContact OG1-N 2.8Å
385A98.1Very high98.1Very high0 Ų027.1 Ų27.10%015%0.148CC..Hα-helixtrans-87.3-36.2-177.200000113P247 M249 A381 A382 L383 C448 F453 A537P247-A385 WeakPolarHBondContact CB-O 3.41Å; M249-A385 HydrophobicContact SD-CB 4Å; A381-A385 PolarHBondContact O-N 2.9Å; A382-A385 WeakPolarHBondContact O-CB 3.42Å; A382-A385 PolarHBondContact O-N 2.8Å; L383-A385 VanDerWaalsContact C-N 3.33Å; A385-C448 HydrophobicContact CB-CB 4.48Å; A385-C448 WeakPolarHBondContact CB-O 3.47Å; A385-F453 HydrophobicContact CB-CD2 3.57Å; A385-F453 HydrophobicContact CB-CE2 3.49Å; A385-F453 VanDerWaalsContact CB-CE2 3.49Å; A385-A537 HydrophobicContact CB-CB 3.71Å
386G96.5Very high98.1Very high0 Ų029.9 Ų29.90%015%0.149CC..SBendtrans-79.1-159.6-179.500000114.6P247 A382P247-G386 WeakPolarHBondContact CA-O 3.3Å; A382-G386 PolarHBondContact O-N 2.84Å
387D97.6Very high98.2Very high59 Ų5932.1 Ų32.132%0.31617%0.166SC..  trans-63.4147.1-178.8-70.1-37.6000112.9P247 V389 P390 W391P247-D387 VanDerWaalsContact CD-OD1 3.22Å; P247-D387 WeakPolarHBondContact CD-OD1 3.49Å; D387-V389 PolarHBondContact O-N 3.03Å; D387-P390 HydrophobicContact CB-CG 3.96Å; D387-P390 WeakPolarHBondContact O-CD 3.38Å; D387-W391 PolarHBondContact O-N 2.86Å
388R98.3Very high98.2Very high0 Ų035.3 Ų35.30%018%0.178CC..Hα-helixtrans-71.6-35.4-172.2-52-49.8-64173.4-2.3113.2R245 G246 D323 T384 W391 A392 D454R245-R388 WeakPolarHBondContact O-CG 3.31Å; R245-R388 PolarHBondContact O-N 2.76Å; G246-R388 WeakPolarHBondContact O-CG 3.48Å; D323-R388 IonicContact OD2-CZ 2.71Å; D323-R388 IonicContact OD2-NE 2.85Å; D323-R388 PolarHBondContact OD2-NE 3.32Å; D323-R388 IonicContact OD2-NH2 3.99Å; D323-R388 PolarHBondContact OD2-NH2 3.43Å; T384-R388 PolarHBondContact O-NH1 2.83Å; R388-W391 PolarHBondContact O-N 2.98Å; R388-A392 WeakPolarHBondContact O-CB 3.46Å; R388-A392 PolarHBondContact O-N 3.07Å; R388-D454 IonicContact CZ-OD1 2.64Å; R388-D454 IonicContact NH1-OD1 3.73Å; R388-D454 PolarHBondContact NH1-OD1 3.08Å; R388-D454 IonicContact NH2-OD1 3.37Å; R388-D454 PolarHBondContact NH2-OD1 2.93Å; R388-D454 IonicContact NH2-OD2 2.67Å
389V98.4Very high98.3Very high40 Ų4031.1 Ų31.124%0.24216%0.159CC..Hα-helixtrans-71.8-48.3-176.4-177.40000112.3R245 E320 D387 W391 A392 K393R245-V389 HydrophobicContact CB-CG2 4.49Å; R245-V389 HydrophobicContact CG-CG2 4.49Å; E320-V389 WeakPolarHBondContact O-CG2 3.26Å; D387-V389 PolarHBondContact O-N 3.03Å; V389-W391 PolarHBondContact O-N 2.89Å; V389-A392 PolarHBondContact O-N 3.4Å; V389-K393 HydrophobicContact CG1-CD 4.28Å; V389-K393 WeakPolarHBondContact O-CG 3.29Å; V389-K393 PolarHBondContact O-N 3.21Å
390P98.3Very high98.2Very high47 Ų4731 Ų3131%0.30517%0.165SC..Hα-helixtrans-55-41.4171.5-27.737000112.5D387 K393 A394 V529D387-P390 HydrophobicContact CB-CG 3.96Å; D387-P390 WeakPolarHBondContact O-CD 3.38Å; P390-K393 PolarHBondContact O-N 3.15Å; P390-A394 WeakPolarHBondContact O-CB 3.45Å; P390-A394 PolarHBondContact O-N 2.74Å; P390-V529 HydrophobicContact CB-CG1 4.48Å
391W98.5Very high98Very high1 Ų140.7 Ų40.70%0.00420%0.202CC..Hα-helixtrans-62.6-47.7175.7-178.5-157.6000112.4P318 L383 T384 D387 R388 V389 K393 A394 R395 F399 L408 W452 D454P318-W391 HydrophobicContact CB-CB 4.28Å; P318-W391 HydrophobicContact CB-CG 3.9Å; P318-W391 VanDerWaalsContact CG-CD1 3.45Å; P318-W391 HydrophobicContact CG-CD2 3.93Å; P318-W391 HydrophobicContact CG-CG 3.74Å; P318-W391 HydrophobicContact CG-CZ2 4.45Å; L383-W391 HydrophobicContact CB-CD2 3.77Å; L383-W391 HydrophobicContact CB-CE3 3.48Å; L383-W391 VanDerWaalsContact CB-CE3 3.48Å; L383-W391 HydrophobicContact CB-CG 4.27Å; L383-W391 HydrophobicContact CB-CZ3 3.96Å; L383-W391 HydrophobicContact CD1-CE3 3.73Å; L383-W391 HydrophobicContact CD1-CH2 4.43Å; L383-W391 HydrophobicContact CD1-CZ3 3.52Å; L383-W391 HydrophobicContact CD2-CE3 4.43Å; L383-W391 HydrophobicContact CG-CE3 4.07Å; L383-W391 HydrophobicContact CG-CZ3 4.32Å; L383-W391 VanDerWaalsContact O-CB 3.24Å; L383-W391 WeakPolarHBondContact O-CB 3.47Å; L383-W391 VanDerWaalsContact O-CG 3.22Å; T384-W391 HydrophobicContact CG2-CZ2 4.25Å; D387-W391 PolarHBondContact O-N 2.86Å; R388-W391 PolarHBondContact O-N 2.98Å; V389-W391 PolarHBondContact O-N 2.89Å; W391-K393 VanDerWaalsContact C-N 3.31Å; W391-K393 PolarHBondContact O-N 3.36Å; W391-A394 HydrophobicContact CE3-CB 4.24Å; W391-A394 PolarHBondContact O-N 2.94Å; W391-R395 HydrophobicContact CD2-CB 4.48Å; W391-R395 HydrophobicContact CE3-CB 4Å; W391-R395 HydrophobicContact CH2-CB 4.03Å; W391-R395 HydrophobicContact CH2-CG 4.19Å; W391-R395 HydrophobicContact CZ2-CB 4.5Å; W391-R395 HydrophobicContact CZ3-CB 3.76Å; W391-R395 HydrophobicContact CZ3-CG 4.41Å; W391-R395 VanDerWaalsContact O-CB 3.31Å; W391-R395 WeakPolarHBondContact O-CB 3.46Å; W391-R395 PolarHBondContact O-N 2.92Å; W391-F399 HydrophobicContact CH2-CD2 4.5Å; W391-F399 HydrophobicContact CZ3-CD2 4.07Å; W391-F399 HydrophobicContact CZ3-CE2 4.1Å; W391-L408 HydrophobicContact CH2-CD1 4.26Å; W391-L408 HydrophobicContact CH2-CD2 4.26Å; W391-L408 HydrophobicContact CZ2-CD1 4.42Å; W391-W452 HydrophobicContact CZ2-CH2 4.49Å; W391-W452 HydrophobicContact CZ2-CZ2 4.15Å; W391-D454 PolarHBondContact NE1-OD2 3.45Å
392A98.7Very high97.9Very high7 Ų743 Ų436%0.05823%0.225CC..Hα-helixtrans-55.4-46.2177.500000112.2P318 G319 E320 R388 V389 R395 Q396P318-A392 HydrophobicContact CB-CB 3.98Å; G319-A392 WeakPolarHBondContact O-CB 3.35Å; E320-A392 HydrophobicContact CG-CB 4.23Å; R388-A392 WeakPolarHBondContact O-CB 3.46Å; R388-A392 PolarHBondContact O-N 3.07Å; V389-A392 PolarHBondContact O-N 3.4Å; A392-R395 PolarHBondContact O-N 2.88Å; A392-Q396 PolarHBondContact O-N 3.27Å; A392-Q396 VanDerWaalsContact O-N 3.08Å
393K98.6Very high97.9Very high110 Ų11046.9 Ų46.948%0.47824%0.242SC..Hα-helixtrans-65.9-46179.1-69.9-179.1177-176.70112E320 V389 P390 W391 R395 Q396 A397E320-K393 HydrophobicContact CG-CG 4.33Å; E320-K393 WeakPolarHBondContact OE2-CE 3.47Å; E320-K393 IonicContact OE2-NZ 2.77Å; V389-K393 HydrophobicContact CG1-CD 4.28Å; V389-K393 WeakPolarHBondContact O-CG 3.29Å; V389-K393 PolarHBondContact O-N 3.21Å; P390-K393 PolarHBondContact O-N 3.15Å; W391-K393 VanDerWaalsContact C-N 3.31Å; W391-K393 PolarHBondContact O-N 3.36Å; K393-R395 VanDerWaalsContact C-N 3.34Å; K393-R395 PolarHBondContact O-N 2.95Å; K393-Q396 PolarHBondContact O-N 3.31Å; K393-A397 WeakPolarHBondContact O-CB 3.47Å; K393-A397 PolarHBondContact O-N 3.22Å
394A98.4Very high97.8Very high3 Ų347.2 Ų47.23%0.02524%0.244CC..Hα-helixtrans-61.3-43.7176.700000111.5L383 P390 W391 Q396 A397 Y398 F399 V529L383-A394 HydrophobicContact CD1-CB 4.48Å; L383-A394 HydrophobicContact CD2-CB 4.26Å; P390-A394 WeakPolarHBondContact O-CB 3.45Å; P390-A394 PolarHBondContact O-N 2.74Å; W391-A394 HydrophobicContact CE3-CB 4.24Å; W391-A394 PolarHBondContact O-N 2.94Å; A394-Q396 VanDerWaalsContact C-N 3.34Å; A394-Q396 PolarHBondContact O-N 2.77Å; A394-A397 PolarHBondContact O-N 3.17Å; A394-Y398 HydrophobicContact CB-CD2 4.19Å; A394-Y398 WeakPolarHBondContact O-CD2 3.46Å; A394-Y398 PolarHBondContact O-N 3.44Å; A394-F399 WeakPolarHBondContact O-CD2 3.16Å; A394-V529 HydrophobicContact CB-CG1 4.09Å
395R98.3Very high97.8Very high64 Ų6451.5 Ų51.524%0.24226%0.262CS..Hα-helixtrans-56.2-46.8175.7-172.3178.6178.9-74.9-2.8111.8P318 W391 A392 K393 F399 S400 L408 E412P318-R395 HydrophobicContact CG-CB 4.34Å; W391-R395 HydrophobicContact CD2-CB 4.48Å; W391-R395 HydrophobicContact CE3-CB 4Å; W391-R395 HydrophobicContact CH2-CB 4.03Å; W391-R395 HydrophobicContact CH2-CG 4.19Å; W391-R395 HydrophobicContact CZ2-CB 4.5Å; W391-R395 HydrophobicContact CZ3-CB 3.76Å; W391-R395 HydrophobicContact CZ3-CG 4.41Å; W391-R395 VanDerWaalsContact O-CB 3.31Å; W391-R395 WeakPolarHBondContact O-CB 3.46Å; W391-R395 PolarHBondContact O-N 2.92Å; A392-R395 PolarHBondContact O-N 2.88Å; K393-R395 VanDerWaalsContact C-N 3.34Å; K393-R395 PolarHBondContact O-N 2.95Å; R395-F399 HydrophobicContact CG-CB 4.47Å; R395-F399 CarbonylContact O-C 3.56Å; R395-F399 WeakPolarHBondContact O-CA 3.5Å; R395-F399 WeakPolarHBondContact O-CB 3.44Å; R395-F399 PolarHBondContact O-N 3.27Å; R395-F399 VanDerWaalsContact O-N 3.1Å; R395-S400 PolarHBondContact O-N 2.8Å; R395-L408 HydrophobicContact CG-CD2 3.85Å; R395-E412 IonicContact CZ-OE1 2.75Å; R395-E412 VanDerWaalsContact CZ-OE1 3.29Å; R395-E412 IonicContact CZ-OE2 3.08Å; R395-E412 IonicContact NE-OE1 3.01Å; R395-E412 PolarHBondContact NE-OE1 3.4Å; R395-E412 VanDerWaalsContact NH2-CD 3.33Å; R395-E412 IonicContact NH2-OE1 3.66Å; R395-E412 PolarHBondContact NH2-OE1 3.41Å; R395-E412 IonicContact NH2-OE2 3.94Å; R395-E412 PolarHBondContact NH2-OE2 2.81Å
396Q98.2Very high97.8Very high127 Ų12758.2 Ų58.259%0.59329%0.294SS*.Hα-helixtrans-66.6-45.1179.2-175.8178.26.300112.4A392 K393 A394 S400A392-Q396 PolarHBondContact O-N 3.27Å; A392-Q396 VanDerWaalsContact O-N 3.08Å; K393-Q396 PolarHBondContact O-N 3.31Å; A394-Q396 VanDerWaalsContact C-N 3.34Å; A394-Q396 PolarHBondContact O-N 2.77Å; Q396-S400 WeakPolarHBondContact O-CB 3.21Å; Q396-S400 PolarHBondContact O-OG 3.17Å
397A98.3Very high97.9Very high63 Ų6358.5 Ų58.552%0.52130%0.296SS..Hα-helixtrans-71.1-46.5-175.700000112.6K393 A394K393-A397 WeakPolarHBondContact O-CB 3.47Å; K393-A397 PolarHBondContact O-N 3.22Å; A394-A397 PolarHBondContact O-N 3.17Å
398Y98.4Very high98Very high68 Ų6855.8 Ų55.827%0.26728%0.281SS..Hα-helixtrans-111.8-18.4-165.3-52.5-65.1000114.4A394 N404 P523 E525 C526A394-Y398 HydrophobicContact CB-CD2 4.19Å; A394-Y398 WeakPolarHBondContact O-CD2 3.46Å; A394-Y398 PolarHBondContact O-N 3.44Å; Y398-N404 VanDerWaalsContact O-CB 3.28Å; Y398-N404 WeakPolarHBondContact O-CB 3.49Å; Y398-N404 PolarHBondContact O-ND2 3.4Å; Y398-P523 HydrophobicContact CD1-CG 3.63Å; Y398-P523 HydrophobicContact CE1-CG 3.83Å; Y398-E525 WeakPolarHBondContact OH-CB 3.35Å; Y398-C526 HydrophobicContact CD1-CB 3.98Å; Y398-C526 HydrophobicContact CD2-CB 3.54Å; Y398-C526 WeakPolarHBondContact CD2-SG 3.27Å; Y398-C526 HydrophobicContact CE1-CB 4.18Å; Y398-C526 HydrophobicContact CE2-CB 3.75Å; Y398-C526 HydrophobicContact CG-CB 3.66Å
399F98.3Very high98Very high6 Ų657.2 Ų57.23%0.02629%0.289CS..SBendtrans-116.911.9-174.4-57.8-93.4000114L380 L383 W391 A394 R395 N404 K405 L408 W520L380-F399 HydrophobicContact CD1-CE1 3.75Å; L380-F399 HydrophobicContact CD1-CE2 4.46Å; L380-F399 HydrophobicContact CD1-CZ 3.4Å; L380-F399 HydrophobicContact CD2-CE1 4.43Å; L383-F399 HydrophobicContact CD1-CE2 3.99Å; L383-F399 HydrophobicContact CD1-CZ 4.2Å; W391-F399 HydrophobicContact CH2-CD2 4.5Å; W391-F399 HydrophobicContact CZ3-CD2 4.07Å; W391-F399 HydrophobicContact CZ3-CE2 4.1Å; A394-F399 WeakPolarHBondContact O-CD2 3.16Å; R395-F399 HydrophobicContact CG-CB 4.47Å; R395-F399 CarbonylContact O-C 3.56Å; R395-F399 WeakPolarHBondContact O-CA 3.5Å; R395-F399 WeakPolarHBondContact O-CB 3.44Å; R395-F399 PolarHBondContact O-N 3.27Å; R395-F399 VanDerWaalsContact O-N 3.1Å; F399-N404 HydrophobicContact CB-CB 4.48Å; F399-N404 HydrophobicContact CD1-CB 3.74Å; F399-N404 HydrophobicContact CE1-CB 4.28Å; F399-N404 HydrophobicContact CG-CB 4.33Å; F399-K405 VanDerWaalsContact O-CA 3.27Å; F399-K405 WeakPolarHBondContact O-CA 3.47Å; F399-K405 WeakPolarHBondContact O-CB 3.44Å; F399-L408 HydrophobicContact CB-CB 4.47Å; F399-L408 HydrophobicContact CB-CD2 3.48Å; F399-L408 VanDerWaalsContact CB-CD2 3.48Å; F399-L408 HydrophobicContact CD1-CB 4.34Å; F399-L408 HydrophobicContact CD1-CD2 4.32Å; F399-L408 HydrophobicContact CG-CD2 4.06Å; F399-W520 HydrophobicContact CD1-CE3 4.37Å; F399-W520 AromaticContact CD1-CZ3 3.83Å; F399-W520 HydrophobicContact CD1-CZ3 3.83Å; F399-W520 AromaticContact CE1-CE3 3.91Å; F399-W520 HydrophobicContact CE1-CE3 3.91Å; F399-W520 AromaticContact CE1-CZ3 3.64Å; F399-W520 HydrophobicContact CE1-CZ3 3.64Å
400S96.1Very high98Very high55 Ų5555.8 Ų55.839%0.38528%0.281SS..SBendtrans-88.3-11-178.261.50000114.3R395 Q396 K405R395-S400 PolarHBondContact O-N 2.8Å; Q396-S400 WeakPolarHBondContact O-CB 3.21Å; Q396-S400 PolarHBondContact O-OG 3.17Å; S400-K405 VanDerWaalsContact O-CD 3.31Å; S400-K405 WeakPolarHBondContact O-CD 3.48Å
401R95.1Very high98Very high204 Ų20453.6 Ų53.677%0.7727%0.267SS*.SBendtrans-145.5173.7-177.9-58.1-177.9-175.4176.11112.4K405R401-K405 WeakPolarHBondContact O-CB 2.99Å; R401-K405 PolarHBondContact O-N 3.06Å; R401-K405 VanDerWaalsContact O-N 3.13Å
402G96.9Very high98Very high47 Ų4753.8 Ų53.849%0.48527%0.268SS..Hα-helixtrans63.3-151.4170.200000115.1K405 Q406G402-K405 PolarHBondContact O-N 3.36Å; G402-Q406 PolarHBondContact O-N 2.96Å
403K96.7Very high97.9Very high82 Ų8257.1 Ų57.136%0.35728%0.281SS..Hα-helixtrans-63.9-41.6179.6-65.4-177.4-172.8152.40112K405 Q406 S407 Q519 E521K403-K405 VanDerWaalsContact C-N 3.33Å; K403-K405 PolarHBondContact O-N 3.36Å; K403-Q406 PolarHBondContact O-N 2.93Å; K403-Q406 VanDerWaalsContact O-N 3.09Å; K403-S407 PolarHBondContact O-N 3.16Å; K403-S407 PolarHBondContact O-OG 2.75Å; K403-Q519 HydrophobicContact CB-CB 4.47Å; K403-Q519 HydrophobicContact CD-CB 4.1Å; K403-E521 HydrophobicContact CD-CG 4.07Å; K403-E521 WeakPolarHBondContact CD-OE1 3.28Å; K403-E521 WeakPolarHBondContact CE-OE1 3.41Å; K403-E521 IonicContact NZ-OE1 3.96Å; K403-E521 PolarHBondContact NZ-OE1 2.93Å
404N98.3Very high97.9Very high9 Ų951.9 Ų51.95%0.04826%0.258CS..Hα-helixtrans-55.6-46177.8-69.1-12000112.5Y398 F399 Q406 S407 L408 W520 E521Y398-N404 VanDerWaalsContact O-CB 3.28Å; Y398-N404 WeakPolarHBondContact O-CB 3.49Å; Y398-N404 PolarHBondContact O-ND2 3.4Å; F399-N404 HydrophobicContact CB-CB 4.48Å; F399-N404 HydrophobicContact CD1-CB 3.74Å; F399-N404 HydrophobicContact CE1-CB 4.28Å; F399-N404 HydrophobicContact CG-CB 4.33Å; N404-Q406 PolarHBondContact O-N 3.24Å; N404-S407 PolarHBondContact O-N 2.98Å; N404-L408 VanDerWaalsContact O-CB 3.27Å; N404-L408 WeakPolarHBondContact O-CB 3.4Å; N404-L408 PolarHBondContact O-N 3.23Å; N404-W520 HydrophobicContact CB-CE3 4.42Å; N404-W520 WeakPolarHBondContact OD1-CA 3.24Å; N404-E521 PolarHBondContact ND2-O 3.47Å; N404-E521 PolarHBondContact OD1-N 2.98Å
405K98.3Very high97.9Very high89 Ų8951.8 Ų51.839%0.38726%0.257SS..Hα-helixtrans-60.7-45.4176.5-173.9-164.9-176.2-73.80111.9F399 S400 R401 G402 K403 S407 D409F399-K405 VanDerWaalsContact O-CA 3.27Å; F399-K405 WeakPolarHBondContact O-CA 3.47Å; F399-K405 WeakPolarHBondContact O-CB 3.44Å; S400-K405 VanDerWaalsContact O-CD 3.31Å; S400-K405 WeakPolarHBondContact O-CD 3.48Å; R401-K405 WeakPolarHBondContact O-CB 2.99Å; R401-K405 PolarHBondContact O-N 3.06Å; R401-K405 VanDerWaalsContact O-N 3.13Å; G402-K405 PolarHBondContact O-N 3.36Å; K403-K405 VanDerWaalsContact C-N 3.33Å; K403-K405 PolarHBondContact O-N 3.36Å; K405-S407 VanDerWaalsContact C-N 3.35Å; K405-D409 IonicContact NZ-OD2 3.71Å; K405-D409 PolarHBondContact NZ-OD2 2.95Å; K405-D409 WeakPolarHBondContact O-CB 3.44Å; K405-D409 PolarHBondContact O-N 3.17Å
406Q98.3Very high97.9Very high141 Ų14148.7 Ų48.766%0.65925%0.246SC*.Hα-helixtrans-63.9-42-178.7-65.9179.336.100111.6G402 K403 N404 A410G402-Q406 PolarHBondContact O-N 2.96Å; K403-Q406 PolarHBondContact O-N 2.93Å; K403-Q406 VanDerWaalsContact O-N 3.09Å; N404-Q406 PolarHBondContact O-N 3.24Å; Q406-A410 PolarHBondContact O-N 3.33Å
407S98.6Very high98Very high6 Ų642.7 Ų42.74%0.04222%0.218CC..Hα-helixtrans-69.3-45.3177.6-65.40000112.1K403 N404 K405 D409 A410 I411 Q519 W520K403-S407 PolarHBondContact O-N 3.16Å; K403-S407 PolarHBondContact O-OG 2.75Å; N404-S407 PolarHBondContact O-N 2.98Å; K405-S407 VanDerWaalsContact C-N 3.35Å; S407-D409 PolarHBondContact O-N 3.35Å; S407-A410 VanDerWaalsContact O-CB 3.31Å; S407-A410 WeakPolarHBondContact O-CB 3.07Å; S407-A410 PolarHBondContact O-N 2.78Å; S407-A410 VanDerWaalsContact O-N 3.1Å; S407-I411 PolarHBondContact O-N 3.21Å; S407-Q519 WeakPolarHBondContact CB-O 3.33Å; S407-Q519 PolarHBondContact OG-N 2.57Å; S407-Q519 VanDerWaalsContact OG-N 3.12Å; S407-Q519 PolarHBondContact OG-O 3.36Å; S407-W520 VanDerWaalsContact CB-CH2 3.4Å
408L98.6Very high98Very high3 Ų339.7 Ų39.72%0.01619%0.193CC..Hα-helixtrans-63.1-42.5174.6-177.463000111.5W391 R395 F399 N404 A410 I411 E412 W452 W520W391-L408 HydrophobicContact CH2-CD1 4.26Å; W391-L408 HydrophobicContact CH2-CD2 4.26Å; W391-L408 HydrophobicContact CZ2-CD1 4.42Å; R395-L408 HydrophobicContact CG-CD2 3.85Å; F399-L408 HydrophobicContact CB-CB 4.47Å; F399-L408 HydrophobicContact CB-CD2 3.48Å; F399-L408 VanDerWaalsContact CB-CD2 3.48Å; F399-L408 HydrophobicContact CD1-CB 4.34Å; F399-L408 HydrophobicContact CD1-CD2 4.32Å; F399-L408 HydrophobicContact CG-CD2 4.06Å; N404-L408 VanDerWaalsContact O-CB 3.27Å; N404-L408 WeakPolarHBondContact O-CB 3.4Å; N404-L408 PolarHBondContact O-N 3.23Å; L408-A410 PolarHBondContact O-N 2.77Å; L408-I411 PolarHBondContact O-N 3.01Å; L408-E412 HydrophobicContact CD1-CG 4.13Å; L408-E412 HydrophobicContact CG-CG 4.17Å; L408-E412 WeakPolarHBondContact O-CG 3.35Å; L408-E412 PolarHBondContact O-N 3.19Å; L408-W452 HydrophobicContact CD1-CH2 3.72Å; L408-W452 HydrophobicContact CD1-CZ2 3.47Å; L408-W452 VanDerWaalsContact CD1-CZ2 3.47Å; L408-W520 HydrophobicContact CB-CZ3 4.45Å
409D98Very high98Very high30 Ų3036.5 Ų36.516%0.1618%0.18CC..Hα-helixtrans-56.8-37.2173-92.3-44.7000111.2K405 S407 K413K405-D409 IonicContact NZ-OD2 3.71Å; K405-D409 PolarHBondContact NZ-OD2 2.95Å; K405-D409 WeakPolarHBondContact O-CB 3.44Å; K405-D409 PolarHBondContact O-N 3.17Å; S407-D409 PolarHBondContact O-N 3.35Å; D409-K413 VanDerWaalsContact CG-NZ 3.3Å; D409-K413 WeakPolarHBondContact O-CB 3.48Å; D409-K413 VanDerWaalsContact O-CG 3.29Å; D409-K413 WeakPolarHBondContact O-CG 3.15Å; D409-K413 PolarHBondContact O-N 2.99Å; D409-K413 IonicContact OD1-NZ 2.86Å; D409-K413 PolarHBondContact OD1-NZ 3.09Å; D409-K413 IonicContact OD2-NZ 2.8Å
410A98.5Very high98Very high10 Ų1036.2 Ų36.28%0.08318%0.179CC..Hα-helixtrans-64.8-40.5175.900000111.6H333 V335 K344 Q406 S407 L408 A414 L518H333-A410 PolarHBondContact NE2-O 2.85Å; V335-A410 HydrophobicContact CG2-CB 4.45Å; K344-A410 HydrophobicContact CD-CB 4.43Å; Q406-A410 PolarHBondContact O-N 3.33Å; S407-A410 VanDerWaalsContact O-CB 3.31Å; S407-A410 WeakPolarHBondContact O-CB 3.07Å; S407-A410 PolarHBondContact O-N 2.78Å; S407-A410 VanDerWaalsContact O-N 3.1Å; L408-A410 PolarHBondContact O-N 2.77Å; A410-A414 WeakPolarHBondContact O-CB 3.48Å; A410-A414 PolarHBondContact O-N 3.1Å; A410-A414 VanDerWaalsContact O-N 3.13Å; A410-L518 HydrophobicContact CB-CD1 4.36Å; A410-L518 HydrophobicContact CB-CD2 4.01Å
411I98.6Very high98.1Very high0 Ų033.7 Ų33.70%016%0.161CC..Hα-helixtrans-68.5-52.9176.7-62.2172.5000111V335 Y342 S407 L408 K413 A414 F417 W452 K455 L518 W520V335-I411 HydrophobicContact CB-CG1 4.35Å; V335-I411 HydrophobicContact CG1-CG1 4.03Å; V335-I411 HydrophobicContact CG2-CG1 4.09Å; Y342-I411 HydrophobicContact CD1-CD1 3.93Å; Y342-I411 HydrophobicContact CE1-CD1 4.22Å; S407-I411 PolarHBondContact O-N 3.21Å; L408-I411 PolarHBondContact O-N 3.01Å; I411-K413 VanDerWaalsContact C-N 3.27Å; I411-K413 PolarHBondContact O-N 3.08Å; I411-A414 VanDerWaalsContact O-CB 3.25Å; I411-A414 WeakPolarHBondContact O-CB 3.49Å; I411-A414 PolarHBondContact O-N 3.45Å; I411-A414 VanDerWaalsContact O-N 3.1Å; I411-F417 HydrophobicContact CG1-CE2 4.48Å; I411-F417 HydrophobicContact CG2-CD2 4.04Å; I411-F417 HydrophobicContact CG2-CE2 4.04Å; I411-W452 HydrophobicContact CD1-CE3 4.09Å; I411-W452 HydrophobicContact CD1-CH2 3.92Å; I411-W452 HydrophobicContact CD1-CZ2 4.42Å; I411-W452 HydrophobicContact CD1-CZ3 3.74Å; I411-W452 HydrophobicContact CG2-CD2 3.5Å; I411-W452 VanDerWaalsContact CG2-CE2 3.43Å; I411-W452 HydrophobicContact CG2-CE3 4.06Å; I411-W452 HydrophobicContact CG2-CG 3.76Å; I411-W452 HydrophobicContact CG2-CH2 4.44Å; I411-W452 HydrophobicContact CG2-CZ2 3.94Å; I411-W452 HydrophobicContact CG2-CZ3 4.49Å; I411-K455 PolarHBondContact O-NZ 2.98Å; I411-K455 VanDerWaalsContact O-NZ 3.09Å; I411-L518 HydrophobicContact CD1-CD1 4.25Å; I411-L518 HydrophobicContact CG1-CD1 3.96Å; I411-W520 HydrophobicContact CD1-CH2 3.92Å; I411-W520 HydrophobicContact CD1-CZ2 3.93Å
412E98.2Very high98.2Very high5 Ų526.6 Ų26.62%0.02314%0.138CC..Hα-helixtrans-61-37-176.5-70-179.8172.600111.5S315 I317 R395 L408 K455S315-E412 WeakPolarHBondContact OG-CA 3.33Å; S315-E412 PolarHBondContact OG-O 2.88Å; I317-E412 HydrophobicContact CD1-CB 4.42Å; I317-E412 VanDerWaalsContact CD1-CD 3.47Å; I317-E412 HydrophobicContact CD1-CG 3.94Å; R395-E412 IonicContact CZ-OE1 2.75Å; R395-E412 VanDerWaalsContact CZ-OE1 3.29Å; R395-E412 IonicContact CZ-OE2 3.08Å; R395-E412 IonicContact NE-OE1 3.01Å; R395-E412 PolarHBondContact NE-OE1 3.4Å; R395-E412 VanDerWaalsContact NH2-CD 3.33Å; R395-E412 IonicContact NH2-OE1 3.66Å; R395-E412 PolarHBondContact NH2-OE1 3.41Å; R395-E412 IonicContact NH2-OE2 3.94Å; R395-E412 PolarHBondContact NH2-OE2 2.81Å; L408-E412 HydrophobicContact CD1-CG 4.13Å; L408-E412 HydrophobicContact CG-CG 4.17Å; L408-E412 WeakPolarHBondContact O-CG 3.35Å; L408-E412 PolarHBondContact O-N 3.19Å; E412-K455 PolarHBondContact O-NZ 3.33Å
413K97.9Very high98.2Very high78 Ų7827.1 Ų27.134%0.33913%0.13SC..THydrogen-bonded Turntrans-89.8-2.7179.1-62.9169.9173.8138.90114.3V328 S331 D409 I411V328-K413 HydrophobicContact CG1-CG 4.24Å; V328-K413 HydrophobicContact CG2-CB 4.3Å; V328-K413 HydrophobicContact CG2-CG 4.47Å; S331-K413 WeakPolarHBondContact CB-O 3.47Å; S331-K413 PolarHBondContact OG-O 3.44Å; D409-K413 VanDerWaalsContact CG-NZ 3.3Å; D409-K413 WeakPolarHBondContact O-CB 3.48Å; D409-K413 VanDerWaalsContact O-CG 3.29Å; D409-K413 WeakPolarHBondContact O-CG 3.15Å; D409-K413 PolarHBondContact O-N 2.99Å; D409-K413 IonicContact OD1-NZ 2.86Å; D409-K413 PolarHBondContact OD1-NZ 3.09Å; D409-K413 IonicContact OD2-NZ 2.8Å; I411-K413 VanDerWaalsContact C-N 3.27Å; I411-K413 PolarHBondContact O-N 3.08Å
414A98.5Very high98.3Very high0 Ų028.4 Ų28.40%014%0.137CC..SBendtrans-57.7151.7176.700000111.5V335 A410 I411 F416 K455V335-A414 HydrophobicContact CB-CB 4.49Å; V335-A414 HydrophobicContact CG2-CB 4.15Å; A410-A414 WeakPolarHBondContact O-CB 3.48Å; A410-A414 PolarHBondContact O-N 3.1Å; A410-A414 VanDerWaalsContact O-N 3.13Å; I411-A414 VanDerWaalsContact O-CB 3.25Å; I411-A414 WeakPolarHBondContact O-CB 3.49Å; I411-A414 PolarHBondContact O-N 3.45Å; I411-A414 VanDerWaalsContact O-N 3.1Å; A414-F416 VanDerWaalsContact C-N 3.3Å; A414-F416 PolarHBondContact O-N 2.83Å; A414-K455 WeakPolarHBondContact O-CE 3.46Å; A414-K455 PolarHBondContact O-NZ 3.47Å
415A98.2Very high98.2Very high0 Ų028.5 Ų28.50%014%0.137CC..SBendtrans-62.7-41.5176.800000111.6F312 N313 S331 H333 I334 L347F312-A415 WeakPolarHBondContact CA-O 3.39Å; N313-A415 PolarHBondContact N-O 2.77Å; N313-A415 WeakPolarHBondContact OD1-CA 3.44Å; S331-A415 PolarHBondContact OG-N 2.68Å; S331-A415 VanDerWaalsContact OG-N 3.12Å; H333-A415 PolarHBondContact O-N 2.75Å; I334-A415 HydrophobicContact CG2-CB 4.28Å; L347-A415 HydrophobicContact CD1-CB 4.21Å
416F98.6Very high98Very high0 Ų024.4 Ų24.40%012%0.12CC..SBendtrans-161170.4170.555.7-85.2000107.8I276 I279 L280 F312 I334 A414 V418 F457 L459I276-F416 HydrophobicContact CG1-CE2 4.35Å; I276-F416 HydrophobicContact CG1-CZ 4.41Å; I276-F416 HydrophobicContact CG2-CZ 4.06Å; I279-F416 HydrophobicContact CB-CE1 4.31Å; I279-F416 HydrophobicContact CB-CZ 4.14Å; I279-F416 HydrophobicContact CD1-CE2 4.07Å; I279-F416 HydrophobicContact CD1-CZ 4.16Å; I279-F416 HydrophobicContact CG2-CD1 3.96Å; I279-F416 HydrophobicContact CG2-CE1 3.48Å; I279-F416 VanDerWaalsContact CG2-CE1 3.48Å; I279-F416 HydrophobicContact CG2-CE2 4.44Å; I279-F416 HydrophobicContact CG2-CZ 3.73Å; L280-F416 HydrophobicContact CD2-CE1 4.09Å; F312-F416 HydrophobicContact CD1-CD1 4.1Å; F312-F416 HydrophobicContact CE1-CD1 4.17Å; I334-F416 HydrophobicContact CG2-CD1 3.9Å; I334-F416 HydrophobicContact CG2-CD2 4.21Å; I334-F416 HydrophobicContact CG2-CE1 3.69Å; I334-F416 HydrophobicContact CG2-CE2 4.02Å; I334-F416 HydrophobicContact CG2-CG 4.16Å; I334-F416 HydrophobicContact CG2-CZ 3.77Å; A414-F416 VanDerWaalsContact C-N 3.3Å; A414-F416 PolarHBondContact O-N 2.83Å; F416-V418 HydrophobicContact CD2-CG2 3.82Å; F416-V418 HydrophobicContact CE2-CG2 3.53Å; F416-F457 HydrophobicContact CB-CD2 4.2Å; F416-F457 HydrophobicContact CB-CE1 3.97Å; F416-F457 HydrophobicContact CB-CE2 3.51Å; F416-F457 HydrophobicContact CB-CZ 3.38Å; F416-F457 HydrophobicContact CD1-CZ 4.15Å; F416-F457 AromaticContact CD2-CE2 3.89Å; F416-F457 HydrophobicContact CD2-CE2 3.89Å; F416-F457 HydrophobicContact CD2-CZ 4.31Å; F416-F457 AromaticContact CG-CE2 3.75Å; F416-F457 HydrophobicContact CG-CE2 3.75Å; F416-F457 AromaticContact CG-CZ 3.72Å; F416-F457 HydrophobicContact CG-CZ 3.72Å; F416-L459 HydrophobicContact CE2-CD2 4.39Å
417F98.9Very high97.8Very high1 Ų120.8 Ų20.80%0.00410%0.101CC..EExtended strand (participates in β ladder)trans-103145.9179.4-163.7-95.2000110.2V335 Y342 I411 W452 K455 F457 T458 L459V335-F417 HydrophobicContact CB-CD2 4.02Å; V335-F417 HydrophobicContact CB-CE2 4.02Å; V335-F417 HydrophobicContact CG1-CD2 4.18Å; V335-F417 HydrophobicContact CG1-CE2 3.65Å; V335-F417 HydrophobicContact CG1-CZ 4.45Å; Y342-F417 HydrophobicContact CD1-CE2 4.07Å; Y342-F417 AromaticContact CD1-CZ 3.86Å; Y342-F417 HydrophobicContact CD1-CZ 3.86Å; Y342-F417 HydrophobicContact CE1-CE2 4.23Å; Y342-F417 AromaticContact CE1-CZ 3.76Å; Y342-F417 HydrophobicContact CE1-CZ 3.76Å; I411-F417 HydrophobicContact CG1-CE2 4.48Å; I411-F417 HydrophobicContact CG2-CD2 4.04Å; I411-F417 HydrophobicContact CG2-CE2 4.04Å; F417-W452 HydrophobicContact CB-CB 4.39Å; F417-W452 HydrophobicContact CD1-CB 3.84Å; F417-W452 HydrophobicContact CD2-CB 3.8Å; F417-W452 HydrophobicContact CD2-CG 4.35Å; F417-W452 HydrophobicContact CE1-CB 3.98Å; F417-W452 HydrophobicContact CE2-CB 3.93Å; F417-W452 HydrophobicContact CE2-CG 4.4Å; F417-W452 HydrophobicContact CG-CB 3.75Å; F417-W452 HydrophobicContact CZ-CB 4.01Å; F417-K455 HydrophobicContact CB-CB 4.11Å; F417-K455 HydrophobicContact CB-CD 4.43Å; F417-K455 HydrophobicContact CB-CG 3.88Å; F417-F457 PolarHBondContact N-O 3.32Å; F417-T458 HydrophobicContact CD1-CG2 3.75Å; F417-T458 CarbonylContact O-C 3.6Å; F417-T458 WeakPolarHBondContact O-CA 3.27Å; F417-L459 PolarHBondContact O-N 2.78Å
418V98.9Very high97.5Very high0 Ų024.9 Ų24.90%012%0.115CC..EExtended strand (participates in β ladder)trans-126.5136.9178.7-178.10000109.5I276 I334 V335 V336 Y337 F416 L420 L459I276-V418 HydrophobicContact CD1-CG1 4.36Å; I276-V418 HydrophobicContact CD1-CG2 4.2Å; I276-V418 HydrophobicContact CG1-CG2 4.39Å; I334-V418 HydrophobicContact CD1-CG2 3.86Å; V335-V418 PolarHBondContact O-N 2.95Å; V336-V418 CarbonylContact C-O 3.54Å; V336-V418 VanDerWaalsContact CA-O 3.3Å; V336-V418 WeakPolarHBondContact CA-O 3.27Å; V336-V418 HydrophobicContact CG1-CB 4.43Å; V336-V418 HydrophobicContact CG1-CG1 4.35Å; V336-V418 HydrophobicContact CG2-CB 4.16Å; Y337-V418 PolarHBondContact N-O 2.91Å; F416-V418 HydrophobicContact CD2-CG2 3.82Å; F416-V418 HydrophobicContact CE2-CG2 3.53Å; V418-L420 HydrophobicContact CG1-CD2 4.29Å; V418-L459 CarbonylContact C-O 3.56Å; V418-L459 VanDerWaalsContact CA-O 3.28Å; V418-L459 WeakPolarHBondContact CA-O 3.42Å; V418-L459 HydrophobicContact CG1-CD2 4.27Å; V418-L459 HydrophobicContact CG2-CB 4.34Å; V418-L459 HydrophobicContact CG2-CD2 4.21Å
419T98.8Very high97.2Very high0 Ų032.7 Ų32.70%015%0.149CC..EExtended strand (participates in β ladder)trans-116.6121.2169.8-58.70000109.1Y337 D421 D450 L459 V461Y337-T419 HydrophobicContact CD1-CG2 3.78Å; Y337-T419 HydrophobicContact CE1-CG2 4.42Å; T419-D421 HydrophobicContact CG2-CB 4.28Å; T419-D450 WeakPolarHBondContact CG2-O 3.44Å; T419-D450 PolarHBondContact OG1-O 2.93Å; T419-D450 VanDerWaalsContact OG1-O 3.08Å; T419-L459 PolarHBondContact N-O 3.46Å; T419-V461 PolarHBondContact O-N 2.86Å
420L98.9Very high97Very high0 Ų039.1 Ų39.10%018%0.178CC..EExtended strand (participates in β ladder)trans-92.596.4164.4-56.9-180000107Q268 A272 V336 Y337 H338 M363 I366 L367 V418 V461Q268-L420 HydrophobicContact CG-CD2 4.44Å; A272-L420 HydrophobicContact CB-CD2 3.92Å; V336-L420 HydrophobicContact CG1-CD1 3.83Å; V336-L420 HydrophobicContact CG1-CG 3.77Å; Y337-L420 PolarHBondContact O-N 2.75Å; H338-L420 HydrophobicContact CB-CB 4.25Å; H338-L420 PolarHBondContact ND1-O 3.03Å; M363-L420 HydrophobicContact CB-CD1 4.1Å; M363-L420 HydrophobicContact SD-CD1 4.13Å; M363-L420 HydrophobicContact SD-CD2 4.46Å; I366-L420 HydrophobicContact CB-CD1 4.46Å; I366-L420 HydrophobicContact CG2-CD1 4.21Å; L367-L420 HydrophobicContact CD2-CB 4Å; L367-L420 HydrophobicContact CD2-CD1 3.93Å; L367-L420 HydrophobicContact CG-CD1 4.06Å; V418-L420 HydrophobicContact CG1-CD2 4.29Å; L420-V461 HydrophobicContact CD2-CB 4.16Å; L420-V461 HydrophobicContact CD2-CG2 4.49Å
421D98.3Very high96.8Very high3 Ų341.3 Ų41.32%0.01619%0.188CC..  trans-79.7141.8-175.8-148-50.3000110.7Q268 T419 I423 R447 R451 I460 V461 F462 K463Q268-D421 PolarHBondContact NE2-O 3.29Å; T419-D421 HydrophobicContact CG2-CB 4.28Å; D421-I423 WeakPolarHBondContact OD1-CG1 3.4Å; D421-I423 PolarHBondContact OD1-N 2.97Å; D421-R447 IonicContact OD1-CZ 3.98Å; D421-R447 IonicContact OD1-NH2 3.89Å; D421-R447 PolarHBondContact OD1-NH2 3.07Å; D421-R451 IonicContact OD2-CZ 3.43Å; D421-R451 IonicContact OD2-NH1 3.25Å; D421-R451 PolarHBondContact OD2-NH1 2.86Å; D421-R451 IonicContact OD2-NH2 3.06Å; D421-R451 PolarHBondContact OD2-NH2 3.2Å; D421-I460 HydrophobicContact CB-CG2 4.48Å; D421-V461 PolarHBondContact N-O 3.48Å; D421-F462 HydrophobicContact CB-CD1 3.79Å; D421-F462 HydrophobicContact CB-CE1 4.07Å; D421-K463 PolarHBondContact O-N 3.44Å
422D96.8Very high96.5Very high54 Ų5443.8 Ų43.829%0.28920%0.204SC..SBendtrans-92.73.1-178.261-33000113.9K339 R447K339-D422 VanDerWaalsContact CE-OD2 3.32Å; K339-D422 WeakPolarHBondContact CE-OD2 3.34Å; K339-D422 HydrophobicContact CG-CB 4.29Å; D422-R447 IonicContact OD1-CZ 3.27Å; D422-R447 VanDerWaalsContact OD1-CZ 3.3Å; D422-R447 IonicContact OD1-NH1 2.68Å; D422-R447 PolarHBondContact OD1-NH1 2.89Å; D422-R447 VanDerWaalsContact OD1-NH1 3.08Å; D422-R447 IonicContact OD1-NH2 3.71Å; D422-R447 PolarHBondContact OD1-NH2 3.25Å
423I97.2Very high96.1Very high59 Ų5947.6 Ų47.630%0.30322%0.222SC..SBendtrans-99.8165.5168.873.1-176.3000112.1D421 Q425 F462 K463D421-I423 WeakPolarHBondContact OD1-CG1 3.4Å; D421-I423 PolarHBondContact OD1-N 2.97Å; I423-Q425 HydrophobicContact CD1-CG 4.07Å; I423-Q425 HydrophobicContact CG1-CG 4.14Å; I423-F462 HydrophobicContact CD1-CE1 4.37Å; I423-F462 HydrophobicContact CG1-CD1 3.93Å; I423-F462 HydrophobicContact CG1-CE1 4.09Å; I423-F462 WeakPolarHBondContact O-CB 3.29Å; I423-K463 WeakPolarHBondContact O-CB 3.47Å; I423-K463 PolarHBondContact O-N 2.99Å
424E96.9Very high96Very high109 Ų10947.1 Ų47.151%0.50923%0.226SC..  trans-102.9137.4173-61.5-179.4-171.800109.7K463 N464E424-K463 HydrophobicContact CG-CB 3.96Å; E424-K463 HydrophobicContact CG-CD 4.3Å; E424-K463 HydrophobicContact CG-CG 4.41Å; E424-N464 HydrophobicContact CB-CB 4.14Å; E424-N464 HydrophobicContact CG-CB 3.84Å
425Q96.6Very high95.9Very high11 Ų1147.1 Ų47.15%0.05123%0.226CC..  trans-142.3173.3177.3-67.7-64.4-6.900110.6I423 Y439 F462 N464 K466I423-Q425 HydrophobicContact CD1-CG 4.07Å; I423-Q425 HydrophobicContact CG1-CG 4.14Å; Q425-Y439 HydrophobicContact CB-CD2 3.67Å; Q425-Y439 HydrophobicContact CB-CE2 4.35Å; Q425-Y439 HydrophobicContact CB-CG 4.3Å; Q425-F462 HydrophobicContact CB-CD1 3.78Å; Q425-F462 HydrophobicContact CB-CD2 3.94Å; Q425-F462 HydrophobicContact CB-CE1 3.84Å; Q425-F462 HydrophobicContact CB-CE2 4.01Å; Q425-F462 HydrophobicContact CB-CG 3.84Å; Q425-F462 HydrophobicContact CB-CZ 3.94Å; Q425-F462 HydrophobicContact CG-CD1 3.57Å; Q425-F462 HydrophobicContact CG-CE1 3.36Å; Q425-F462 HydrophobicContact CG-CE2 4.37Å; Q425-F462 HydrophobicContact CG-CG 4.17Å; Q425-F462 HydrophobicContact CG-CZ 3.79Å; Q425-N464 PolarHBondContact O-ND2 3.34Å; Q425-N464 PolarHBondContact O-OD1 3.26Å; Q425-K466 VanDerWaalsContact O-CB 3.3Å; Q425-K466 WeakPolarHBondContact O-CB 3.37Å; Q425-K466 VanDerWaalsContact O-CG 3.24Å; Q425-K466 WeakPolarHBondContact O-CG 3.07Å
426G94.6Very high95.8Very high2 Ų247.4 Ų47.42%0.02123%0.227CC..SBendtrans115.8175.5178.700000112.4R428 S435G426-R428 PolarHBondContact O-N 2.7Å; G426-S435 WeakPolarHBondContact O-CB 3.22Å
427Y93.9Very high95.8Very high66 Ų6647.9 Ų47.926%0.25923%0.23SC..  trans-61126.3-179.4179.2-98.8000112.1L260 Y261 K429 P432 L436L260-Y427 HydrophobicContact CD1-CD2 3.72Å; L260-Y427 HydrophobicContact CD1-CE2 4.46Å; L260-Y427 HydrophobicContact CD1-CG 3.83Å; L260-Y427 HydrophobicContact CG-CG 4.45Å; Y261-Y427 HydrophobicContact CD1-CD1 4.01Å; Y261-Y427 AromaticContact CD1-CE1 3.93Å; Y261-Y427 HydrophobicContact CD1-CE1 3.93Å; Y261-Y427 HydrophobicContact CE1-CD1 4.06Å; Y261-Y427 AromaticContact CE1-CE1 3.64Å; Y261-Y427 HydrophobicContact CE1-CE1 3.64Å; Y261-Y427 AromaticContact CE1-CZ 3.94Å; Y427-K429 HydrophobicContact CE1-CB 4.32Å; Y427-P432 HydrophobicContact CD2-CB 4.35Å; Y427-P432 HydrophobicContact CE2-CB 3.48Å; Y427-P432 VanDerWaalsContact CE2-CB 3.48Å; Y427-L436 HydrophobicContact CD2-CD1 4.12Å; Y427-L436 HydrophobicContact CD2-CD2 4.19Å; Y427-L436 HydrophobicContact CD2-CG 4.07Å
428R93.4Very high95.7Very high91 Ų9152 Ų5234%0.34325%0.25SS..  trans-115.2129170.7-62.6-172.9-63.1-102-0.5109.1G426 E430 D431 P432 S435G426-R428 PolarHBondContact O-N 2.7Å; R428-E430 PolarHBondContact O-N 3.23Å; R428-D431 IonicContact NH2-OD2 3.48Å; R428-D431 CarbonylContact O-C 3.56Å; R428-D431 VanDerWaalsContact O-C 3.28Å; R428-D431 PolarHBondContact O-N 3.38Å; R428-P432 VanDerWaalsContact O-CA 3.29Å; R428-P432 WeakPolarHBondContact O-CA 3.32Å; R428-S435 PolarHBondContact N-OG 2.71Å
429K91.1Very high95.6Very high168 Ų16852.2 Ų52.273%0.7325%0.251SS*.THydrogen-bonded Turntrans-68.3-29.2-175.4-174.1178.9177.2-176.50112.2Y427 D431Y427-K429 HydrophobicContact CE1-CB 4.32Å; K429-D431 VanDerWaalsContact C-N 3.27Å; K429-D431 PolarHBondContact O-N 3.28Å
430E94.4Very high95.6Very high164 Ų16452.2 Ų52.277%0.76625%0.251SS*.THydrogen-bonded Turntrans-72.7-23.8-178.2-56.469.5-146.900112R428R428-E430 PolarHBondContact O-N 3.23Å
431D94.2Very high95.5Very high56 Ų5655 Ų5530%0.29926%0.263SS..SBendtrans-152.568.3-173.6177.227.4000110R428 K429 T434 S435R428-D431 IonicContact NH2-OD2 3.48Å; R428-D431 CarbonylContact O-C 3.56Å; R428-D431 VanDerWaalsContact O-C 3.28Å; R428-D431 PolarHBondContact O-N 3.38Å; K429-D431 VanDerWaalsContact C-N 3.27Å; K429-D431 PolarHBondContact O-N 3.28Å; D431-T434 WeakPolarHBondContact OD1-CB 3.5Å; D431-T434 PolarHBondContact OD1-OG1 2.79Å; D431-T434 WeakPolarHBondContact OD2-CB 3.49Å; D431-T434 PolarHBondContact OD2-OG1 2.98Å; D431-S435 WeakPolarHBondContact O-CB 3.31Å; D431-S435 PolarHBondContact O-N 3.45Å; D431-S435 VanDerWaalsContact O-N 3.1Å; D431-S435 PolarHBondContact O-OG 2.87Å
432P91.2Very high95.5Very high52 Ų5255.3 Ų55.334%0.33827%0.265SS..Hα-helixtrans-66.9-40.5-167.225.1-34.5000113.2Y427 R428 S435 L436Y427-P432 HydrophobicContact CD2-CB 4.35Å; Y427-P432 HydrophobicContact CE2-CB 3.48Å; Y427-P432 VanDerWaalsContact CE2-CB 3.48Å; R428-P432 VanDerWaalsContact O-CA 3.29Å; R428-P432 WeakPolarHBondContact O-CA 3.32Å; P432-S435 PolarHBondContact O-OG 2.98Å; P432-S435 VanDerWaalsContact O-OG 3.13Å; P432-L436 VanDerWaalsContact O-CG 3.31Å; P432-L436 WeakPolarHBondContact O-CG 3.14Å; P432-L436 PolarHBondContact O-N 3.31Å
433E91.3Very high95.6Very high86 Ų8652.7 Ų52.740%0.40225%0.252SS..Hα-helixtrans-68.1-61.4-178-65-177.8-169.400110.6S435 L436 D437 H547E433-S435 VanDerWaalsContact C-N 3.25Å; E433-S435 PolarHBondContact O-N 3.26Å; E433-L436 PolarHBondContact O-N 2.81Å; E433-L436 VanDerWaalsContact O-N 3.1Å; E433-D437 VanDerWaalsContact O-CG 3.26Å; E433-D437 PolarHBondContact O-N 2.57Å; E433-H547 IonicContact OE2-CE1 2.73Å
434T95.4Very high95.6Very high67 Ų6749.9 Ų49.941%0.41124%0.237SC..Hα-helixtrans-59.9-36.4-177.8-36.70000112.1D431 D437 M438D431-T434 WeakPolarHBondContact OD1-CB 3.5Å; D431-T434 PolarHBondContact OD1-OG1 2.79Å; D431-T434 WeakPolarHBondContact OD2-CB 3.49Å; D431-T434 PolarHBondContact OD2-OG1 2.98Å; T434-D437 PolarHBondContact O-N 2.74Å; T434-M438 HydrophobicContact CG2-CG 4.34Å; T434-M438 HydrophobicContact CG2-SD 4.26Å; T434-M438 WeakPolarHBondContact O-CB 3.4Å; T434-M438 VanDerWaalsContact O-CG 3.25Å; T434-M438 WeakPolarHBondContact O-CG 3.35Å; T434-M438 PolarHBondContact O-N 2.8Å
435S96.6Very high95.6Very high0 Ų045.6 Ų45.60%022%0.217CC..Hα-helixtrans-66.1-37.9178.866.10000113.1G426 R428 D431 P432 E433 Y439G426-S435 WeakPolarHBondContact O-CB 3.22Å; R428-S435 PolarHBondContact N-OG 2.71Å; D431-S435 WeakPolarHBondContact O-CB 3.31Å; D431-S435 PolarHBondContact O-N 3.45Å; D431-S435 VanDerWaalsContact O-N 3.1Å; D431-S435 PolarHBondContact O-OG 2.87Å; P432-S435 PolarHBondContact O-OG 2.98Å; P432-S435 VanDerWaalsContact O-OG 3.13Å; E433-S435 VanDerWaalsContact C-N 3.25Å; E433-S435 PolarHBondContact O-N 3.26Å; S435-Y439 WeakPolarHBondContact O-CB 3.38Å; S435-Y439 PolarHBondContact O-N 2.81Å; S435-Y439 VanDerWaalsContact O-N 3.13Å
436L96.3Very high95.7Very high6 Ų645.9 Ų45.93%0.03122%0.223CC..Hα-helixtrans-72.4-35.4174.8-71176.2000112M257 L260 Y427 P432 E433 Y439 A440 S548M257-L436 WeakPolarHBondContact CE-O 3.36Å; M257-L436 HydrophobicContact SD-CD2 4.42Å; L260-L436 HydrophobicContact CD1-CD1 4.4Å; L260-L436 HydrophobicContact CD1-CD2 3.96Å; Y427-L436 HydrophobicContact CD2-CD1 4.12Å; Y427-L436 HydrophobicContact CD2-CD2 4.19Å; Y427-L436 HydrophobicContact CD2-CG 4.07Å; P432-L436 VanDerWaalsContact O-CG 3.31Å; P432-L436 WeakPolarHBondContact O-CG 3.14Å; P432-L436 PolarHBondContact O-N 3.31Å; E433-L436 PolarHBondContact O-N 2.81Å; E433-L436 VanDerWaalsContact O-N 3.1Å; L436-Y439 HydrophobicContact CD2-CD1 4.46Å; L436-Y439 PolarHBondContact O-N 2.87Å; L436-A440 WeakPolarHBondContact O-CB 3.45Å; L436-A440 PolarHBondContact O-N 3.41Å; L436-S548 WeakPolarHBondContact CD1-O 3.49Å
437D97.4Very high95.8Very high11 Ų1149.5 Ų49.56%0.05924%0.236CC..Hα-helixtrans-68-46.8178.5-63.8-14.1000111.6E433 T434 Y439 A440 K441 H547 S548 H745E433-D437 VanDerWaalsContact O-CG 3.26Å; E433-D437 PolarHBondContact O-N 2.57Å; T434-D437 PolarHBondContact O-N 2.74Å; D437-Y439 PolarHBondContact O-N 2.99Å; D437-A440 PolarHBondContact O-N 2.61Å; D437-K441 WeakPolarHBondContact O-CB 3.4Å; D437-K441 WeakPolarHBondContact O-CG 3.46Å; D437-K441 PolarHBondContact O-N 3.19Å; D437-H547 WeakPolarHBondContact OD1-CA 3.3Å; D437-H547 IonicContact OD2-ND1 3.71Å; D437-S548 PolarHBondContact OD1-N 2.74Å; D437-H745 IonicContact OD2-CE1 2.79Å; D437-H745 PolarHBondContact OD2-CE1 2.85Å; D437-H745 VanDerWaalsContact OD2-CE1 3.25Å; D437-H745 IonicContact OD2-NE2 2.74Å; D437-H745 PolarHBondContact OD2-NE2 3.01Å
438M97.4Very high96Very high86 Ų8646.5 Ų46.542%0.42422%0.224SC..Hα-helixtrans-59.6-38.9173.5-73.1-178.170.400111.7T434 S442T434-M438 HydrophobicContact CG2-CG 4.34Å; T434-M438 HydrophobicContact CG2-SD 4.26Å; T434-M438 WeakPolarHBondContact O-CB 3.4Å; T434-M438 VanDerWaalsContact O-CG 3.25Å; T434-M438 WeakPolarHBondContact O-CG 3.35Å; T434-M438 PolarHBondContact O-N 2.8Å; M438-S442 VanDerWaalsContact O-CB 3.28Å; M438-S442 WeakPolarHBondContact O-CB 3.19Å; M438-S442 PolarHBondContact O-N 2.97Å
439Y97.8Very high96.2Very high6 Ų643.9 Ų43.92%0.02422%0.215CC..Hα-helixtrans-68.1-43.9178.2-180-147.6000111.8M257 D258 Q425 S435 L436 D437 S442 L443 F462 M467M257-Y439 HydrophobicContact CB-CE1 3.78Å; M257-Y439 HydrophobicContact CE-CD1 3.76Å; M257-Y439 HydrophobicContact CE-CE1 4.37Å; M257-Y439 HydrophobicContact CE-CG 4.23Å; M257-Y439 HydrophobicContact CG-CD1 3.96Å; M257-Y439 HydrophobicContact CG-CE1 3.59Å; M257-Y439 HydrophobicContact SD-CD1 3.68Å; M257-Y439 HydrophobicContact SD-CE1 3.76Å; D258-Y439 WeakPolarHBondContact CB-OH 3.38Å; D258-Y439 PolarHBondContact N-OH 3.31Å; Q425-Y439 HydrophobicContact CB-CD2 3.67Å; Q425-Y439 HydrophobicContact CB-CE2 4.35Å; Q425-Y439 HydrophobicContact CB-CG 4.3Å; S435-Y439 WeakPolarHBondContact O-CB 3.38Å; S435-Y439 PolarHBondContact O-N 2.81Å; S435-Y439 VanDerWaalsContact O-N 3.13Å; L436-Y439 HydrophobicContact CD2-CD1 4.46Å; L436-Y439 PolarHBondContact O-N 2.87Å; D437-Y439 PolarHBondContact O-N 2.99Å; Y439-S442 PolarHBondContact O-N 3.44Å; Y439-L443 HydrophobicContact CD2-CD1 3.86Å; Y439-L443 HydrophobicContact CD2-CG 3.95Å; Y439-L443 HydrophobicContact CE1-CD1 4.44Å; Y439-L443 HydrophobicContact CE2-CD1 3.54Å; Y439-L443 HydrophobicContact CE2-CD2 4.07Å; Y439-L443 HydrophobicContact CE2-CG 3.83Å; Y439-L443 HydrophobicContact CG-CD1 4.44Å; Y439-L443 VanDerWaalsContact O-CG 3.3Å; Y439-L443 WeakPolarHBondContact O-CG 3.43Å; Y439-L443 PolarHBondContact O-N 2.98Å; Y439-F462 HydrophobicContact CD2-CE2 4.01Å; Y439-F462 HydrophobicContact CD2-CZ 4.4Å; Y439-F462 HydrophobicContact CE2-CD2 4.2Å; Y439-F462 AromaticContact CE2-CE2 3.65Å; Y439-F462 HydrophobicContact CE2-CE2 3.65Å; Y439-F462 HydrophobicContact CE2-CZ 4.44Å; Y439-M467 PolarHBondContact OH-O 3.03Å
440A97.6Very high96.5Very high0 Ų035.9 Ų35.90%018%0.18CC..Hα-helixtrans-57.8-50.6173.300000111.5F255 M257 L436 D437 S442 L443 I444 F546F255-A440 HydrophobicContact CE1-CB 4.28Å; F255-A440 HydrophobicContact CE2-CB 3.95Å; F255-A440 HydrophobicContact CZ-CB 3.57Å; M257-A440 HydrophobicContact CE-CB 3.62Å; L436-A440 WeakPolarHBondContact O-CB 3.45Å; L436-A440 PolarHBondContact O-N 3.41Å; D437-A440 PolarHBondContact O-N 2.61Å; A440-S442 VanDerWaalsContact C-N 3.33Å; A440-S442 PolarHBondContact O-N 3.26Å; A440-L443 PolarHBondContact O-N 2.71Å; A440-L443 VanDerWaalsContact O-N 3.17Å; A440-I444 WeakPolarHBondContact O-CG2 3.3Å; A440-I444 PolarHBondContact O-N 3.38Å; A440-F546 HydrophobicContact CB-CD1 4.21Å; A440-F546 HydrophobicContact CB-CG 4.35Å
441K97.6Very high96.6Very high58 Ų5828.1 Ų28.125%0.25214%0.144SC..Hα-helixtrans-56.7-45176.4-76.1-174.9178.2-1660112.1D437 L443 I444 H445 G446 V544 F546D437-K441 WeakPolarHBondContact O-CB 3.4Å; D437-K441 WeakPolarHBondContact O-CG 3.46Å; D437-K441 PolarHBondContact O-N 3.19Å; K441-L443 VanDerWaalsContact C-N 3.32Å; K441-L443 PolarHBondContact O-N 2.63Å; K441-I444 WeakPolarHBondContact O-CG2 3.21Å; K441-I444 PolarHBondContact O-N 3.36Å; K441-H445 WeakPolarHBondContact CB-NE2 3.37Å; K441-H445 PolarHBondContact O-CE1 2.85Å; K441-H445 PolarHBondContact O-N 2.91Å; K441-H445 PolarHBondContact O-ND1 3.47Å; K441-G446 PolarHBondContact O-N 3.03Å; K441-V544 WeakPolarHBondContact CE-O 3.38Å; K441-V544 PolarHBondContact NZ-O 2.95Å; K441-F546 HydrophobicContact CG-CB 4.21Å; K441-F546 HydrophobicContact CG-CD2 3.71Å; K441-F546 HydrophobicContact CG-CG 4.32Å
442S97.9Very high96.8Very high9 Ų925.6 Ų25.66%0.06313%0.13CC..Hα-helixtrans-66.4-31.7178.8-1730000113.6M438 Y439 A440 G446 R451 F462M438-S442 VanDerWaalsContact O-CB 3.28Å; M438-S442 WeakPolarHBondContact O-CB 3.19Å; M438-S442 PolarHBondContact O-N 2.97Å; Y439-S442 PolarHBondContact O-N 3.44Å; A440-S442 VanDerWaalsContact C-N 3.33Å; A440-S442 PolarHBondContact O-N 3.26Å; S442-G446 WeakPolarHBondContact O-CA 3.43Å; S442-G446 PolarHBondContact O-N 2.9Å; S442-R451 PolarHBondContact O-NH2 3.11Å; S442-F462 WeakPolarHBondContact OG-CE1 3.04Å; S442-F462 WeakPolarHBondContact OG-CZ 3.42Å
443L98.2Very high97.2Very high0 Ų023.1 Ų23.10%011%0.114CC..Hα-helixtrans-78.7-36.5176.3-68.3173.6000113.2F255 A256 M257 Y439 A440 K441 I460 F462 N470F255-L443 HydrophobicContact CB-CB 3.76Å; F255-L443 HydrophobicContact CD2-CB 4Å; F255-L443 HydrophobicContact CD2-CD1 3.9Å; F255-L443 HydrophobicContact CG-CB 4.03Å; A256-L443 WeakPolarHBondContact O-CD1 3.29Å; M257-L443 HydrophobicContact CB-CD1 4.4Å; M257-L443 HydrophobicContact CG-CD1 3.65Å; Y439-L443 HydrophobicContact CD2-CD1 3.86Å; Y439-L443 HydrophobicContact CD2-CG 3.95Å; Y439-L443 HydrophobicContact CE1-CD1 4.44Å; Y439-L443 HydrophobicContact CE2-CD1 3.54Å; Y439-L443 HydrophobicContact CE2-CD2 4.07Å; Y439-L443 HydrophobicContact CE2-CG 3.83Å; Y439-L443 HydrophobicContact CG-CD1 4.44Å; Y439-L443 VanDerWaalsContact O-CG 3.3Å; Y439-L443 WeakPolarHBondContact O-CG 3.43Å; Y439-L443 PolarHBondContact O-N 2.98Å; A440-L443 PolarHBondContact O-N 2.71Å; A440-L443 VanDerWaalsContact O-N 3.17Å; K441-L443 VanDerWaalsContact C-N 3.32Å; K441-L443 PolarHBondContact O-N 2.63Å; L443-I460 HydrophobicContact CD2-CB 4.17Å; L443-I460 HydrophobicContact CD2-CD1 3.65Å; L443-I460 HydrophobicContact CD2-CG2 4.45Å; L443-F462 HydrophobicContact CD2-CE2 3.85Å; L443-F462 HydrophobicContact CD2-CZ 4.11Å; L443-N470 WeakPolarHBondContact O-CB 3.47Å; L443-N470 PolarHBondContact O-ND2 3.28Å; L443-N470 VanDerWaalsContact O-ND2 3.15Å
444I97.5Very high97.5Very high0 Ų019.1 Ų19.10%010%0.095CC..Hα-helixtrans-79.3-46.6-178-164172.5000112.9F255 A440 K441 F453 N470 F546F255-I444 HydrophobicContact CD1-CB 3.7Å; F255-I444 HydrophobicContact CD1-CD1 4.16Å; F255-I444 HydrophobicContact CD1-CG1 4.13Å; F255-I444 HydrophobicContact CE1-CB 4.32Å; F255-I444 HydrophobicContact CE1-CD1 4.46Å; F255-I444 HydrophobicContact CG-CB 4.4Å; A440-I444 WeakPolarHBondContact O-CG2 3.3Å; A440-I444 PolarHBondContact O-N 3.38Å; K441-I444 WeakPolarHBondContact O-CG2 3.21Å; K441-I444 PolarHBondContact O-N 3.36Å; I444-F453 WeakPolarHBondContact O-CE1 3.21Å; I444-N470 PolarHBondContact O-ND2 2.79Å; I444-F546 HydrophobicContact CD1-CE2 4.15Å; I444-F546 HydrophobicContact CD1-CZ 3.62Å; I444-F546 HydrophobicContact CG2-CE2 3.72Å; I444-F546 HydrophobicContact CG2-CZ 4.07Å
445H97.9Very high97.7Very high19 Ų1916 Ų169%0.0888%0.076CC..THydrogen-bonded Turntrans-124.8-18.9-175.358.969.9000114.3M249 V250 K441 R447 C448 A541M249-H445 HydrophobicContact CE-CB 3.64Å; M249-H445 HydrophobicContact CG-CB 3.74Å; M249-H445 HydrophobicContact SD-CB 3.41Å; M249-H445 WeakPolarHBondContact SD-CB 3.17Å; V250-H445 HydrophobicContact CG2-CB 4.43Å; K441-H445 WeakPolarHBondContact CB-NE2 3.37Å; K441-H445 PolarHBondContact O-CE1 2.85Å; K441-H445 PolarHBondContact O-N 2.91Å; K441-H445 PolarHBondContact O-ND1 3.47Å; H445-R447 PolarHBondContact O-N 3.31Å; H445-C448 WeakPolarHBondContact O-CA 3.4Å; H445-C448 PolarHBondContact O-N 3.08Å; H445-A541 HydrophobicContact CB-CB 4.07Å
446G97.1Very high97.7Very high16 Ų1616 Ų1617%0.1658%0.076CC..THydrogen-bonded Turntrans53.9-133.8-178.900000111.2K441 S442 C448K441-G446 PolarHBondContact O-N 3.03Å; S442-G446 WeakPolarHBondContact O-CA 3.43Å; S442-G446 PolarHBondContact O-N 2.9Å; G446-C448 VanDerWaalsContact C-N 3.32Å
447R97.6Very high97.8Very high78 Ų7815.8 Ų15.829%0.2948%0.075SC..THydrogen-bonded Turntrans-94.515.8171.6-59.6175.8-144.4158.517.1112.9D421 D422 H445 Y449 D450D421-R447 IonicContact OD1-CZ 3.98Å; D421-R447 IonicContact OD1-NH2 3.89Å; D421-R447 PolarHBondContact OD1-NH2 3.07Å; D422-R447 IonicContact OD1-CZ 3.27Å; D422-R447 VanDerWaalsContact OD1-CZ 3.3Å; D422-R447 IonicContact OD1-NH1 2.68Å; D422-R447 PolarHBondContact OD1-NH1 2.89Å; D422-R447 VanDerWaalsContact OD1-NH1 3.08Å; D422-R447 IonicContact OD1-NH2 3.71Å; D422-R447 PolarHBondContact OD1-NH2 3.25Å; H445-R447 PolarHBondContact O-N 3.31Å; R447-Y449 HydrophobicContact CB-CD1 4.02Å; R447-Y449 HydrophobicContact CB-CE1 3.55Å; R447-Y449 HydrophobicContact CB-CE2 4.37Å; R447-Y449 WeakPolarHBondContact CD-OH 3.41Å; R447-Y449 WeakPolarHBondContact O-CD1 3.23Å; R447-Y449 WeakPolarHBondContact O-CE1 3.35Å; R447-Y449 PolarHBondContact O-N 3.45Å; R447-D450 PolarHBondContact N-OD1 3.47Å; R447-D450 PolarHBondContact N-OD2 3.44Å; R447-D450 IonicContact NE-OD2 3.5Å
448C98.4Very high97.8Very high3 Ų315.2 Ų15.22%0.027%0.072CC..SBendtrans66.4-4-175.6-52.60000115.7M249 A382 A385 H445 G446 L534 A537M249-C448 HydrophobicContact SD-CB 4.21Å; A382-C448 WeakPolarHBondContact CA-O 3.46Å; A385-C448 HydrophobicContact CB-CB 4.48Å; A385-C448 WeakPolarHBondContact CB-O 3.47Å; H445-C448 WeakPolarHBondContact O-CA 3.4Å; H445-C448 PolarHBondContact O-N 3.08Å; G446-C448 VanDerWaalsContact C-N 3.32Å; C448-L534 HydrophobicContact CB-CD1 3.81Å; C448-A537 HydrophobicContact CB-CB 3.73Å
449Y97.5Very high97.9Very high36 Ų3611.1 Ų11.114%0.1415%0.052CC..SBendtrans-132.8-2.617862.1-101.8000114.3Q378 K379 A381 R447 L534Q378-Y449 VanDerWaalsContact O-CD2 3.24Å; Q378-Y449 WeakPolarHBondContact O-CD2 3.35Å; K379-Y449 HydrophobicContact CB-CG 4.48Å; K379-Y449 HydrophobicContact CG-CD1 4.3Å; K379-Y449 HydrophobicContact CG-CG 4.27Å; A381-Y449 WeakPolarHBondContact CB-O 3.22Å; R447-Y449 HydrophobicContact CB-CD1 4.02Å; R447-Y449 HydrophobicContact CB-CE1 3.55Å; R447-Y449 HydrophobicContact CB-CE2 4.37Å; R447-Y449 WeakPolarHBondContact CD-OH 3.41Å; R447-Y449 WeakPolarHBondContact O-CD1 3.23Å; R447-Y449 WeakPolarHBondContact O-CE1 3.35Å; R447-Y449 PolarHBondContact O-N 3.45Å; Y449-L534 HydrophobicContact CD1-CD1 3.83Å; Y449-L534 HydrophobicContact CD1-CD2 4.22Å
450D97.1Very high98Very high1 Ų110.9 Ų10.91%0.0055%0.051CC..SBendtrans-102.514.5-175.160.7-11.3000112.8Y337 T419 R447Y337-D450 HydrophobicContact CD1-CB 4.27Å; Y337-D450 HydrophobicContact CE1-CB 3.47Å; Y337-D450 VanDerWaalsContact CE1-CB 3.47Å; T419-D450 WeakPolarHBondContact CG2-O 3.44Å; T419-D450 PolarHBondContact OG1-O 2.93Å; T419-D450 VanDerWaalsContact OG1-O 3.08Å; R447-D450 PolarHBondContact N-OD1 3.47Å; R447-D450 PolarHBondContact N-OD2 3.44Å; R447-D450 IonicContact NE-OD2 3.5Å
451R97.2Very high98Very high0 Ų010.9 Ų10.90%05%0.051CC..SBendtrans-135153.9175.1-50.8-66.6179.8-99.40.3109.3A381 D421 S442 F453A381-R451 WeakPolarHBondContact CB-O 3.36Å; D421-R451 IonicContact OD2-CZ 3.43Å; D421-R451 IonicContact OD2-NH1 3.25Å; D421-R451 PolarHBondContact OD2-NH1 2.86Å; D421-R451 IonicContact OD2-NH2 3.06Å; D421-R451 PolarHBondContact OD2-NH2 3.2Å; S442-R451 PolarHBondContact O-NH2 3.11Å; R451-F453 HydrophobicContact CB-CD1 4.22Å; R451-F453 HydrophobicContact CB-CD2 4.36Å; R451-F453 HydrophobicContact CB-CE1 3.7Å; R451-F453 HydrophobicContact CB-CE2 3.89Å; R451-F453 HydrophobicContact CB-CZ 3.55Å; R451-F453 HydrophobicContact CG-CE1 4.01Å; R451-F453 HydrophobicContact CG-CZ 3.82Å
452W98.4Very high98.1Very high4 Ų48.1 Ų8.12%0.0154%0.039CC..  trans-103.189.6170.2-158.8-88.8000109.9Y342 A381 T384 W391 L408 I411 F417 D454 K455 T458Y342-W452 HydrophobicContact CE1-CE3 4.21Å; Y342-W452 HydrophobicContact CE1-CZ3 4.32Å; A381-W452 HydrophobicContact CB-CE3 3.93Å; A381-W452 HydrophobicContact CB-CZ3 4.21Å; T384-W452 HydrophobicContact CG2-CD2 3.89Å; T384-W452 HydrophobicContact CG2-CE3 4.19Å; T384-W452 HydrophobicContact CG2-CG 4.46Å; T384-W452 HydrophobicContact CG2-CH2 4.07Å; T384-W452 HydrophobicContact CG2-CZ2 3.74Å; T384-W452 HydrophobicContact CG2-CZ3 4.28Å; W391-W452 HydrophobicContact CZ2-CH2 4.49Å; W391-W452 HydrophobicContact CZ2-CZ2 4.15Å; L408-W452 HydrophobicContact CD1-CH2 3.72Å; L408-W452 HydrophobicContact CD1-CZ2 3.47Å; L408-W452 VanDerWaalsContact CD1-CZ2 3.47Å; I411-W452 HydrophobicContact CD1-CE3 4.09Å; I411-W452 HydrophobicContact CD1-CH2 3.92Å; I411-W452 HydrophobicContact CD1-CZ2 4.42Å; I411-W452 HydrophobicContact CD1-CZ3 3.74Å; I411-W452 HydrophobicContact CG2-CD2 3.5Å; I411-W452 VanDerWaalsContact CG2-CE2 3.43Å; I411-W452 HydrophobicContact CG2-CE3 4.06Å; I411-W452 HydrophobicContact CG2-CG 3.76Å; I411-W452 HydrophobicContact CG2-CH2 4.44Å; I411-W452 HydrophobicContact CG2-CZ2 3.94Å; I411-W452 HydrophobicContact CG2-CZ3 4.49Å; F417-W452 HydrophobicContact CB-CB 4.39Å; F417-W452 HydrophobicContact CD1-CB 3.84Å; F417-W452 HydrophobicContact CD2-CB 3.8Å; F417-W452 HydrophobicContact CD2-CG 4.35Å; F417-W452 HydrophobicContact CE1-CB 3.98Å; F417-W452 HydrophobicContact CE2-CB 3.93Å; F417-W452 HydrophobicContact CE2-CG 4.4Å; F417-W452 HydrophobicContact CG-CB 3.75Å; F417-W452 HydrophobicContact CZ-CB 4.01Å; W452-D454 PolarHBondContact O-N 3.14Å; W452-D454 VanDerWaalsContact O-N 3.16Å; W452-K455 WeakPolarHBondContact O-CB 3.39Å; W452-K455 PolarHBondContact O-N 2.94Å; W452-T458 PolarHBondContact O-OG1 3.05Å
453F98.6Very high98.1Very high0 Ų013.2 Ų13.20%06%0.06CC..THydrogen-bonded Turntrans-66.4-19.3-169.6-64.4-71.5000114.1I248 M249 N253 T384 A385 I444 R451 K455I248-F453 HydrophobicContact CD1-CB 4.48Å; I248-F453 HydrophobicContact CG1-CB 4.49Å; M249-F453 HydrophobicContact CB-CD1 3.99Å; M249-F453 HydrophobicContact CB-CD2 4.35Å; M249-F453 HydrophobicContact CB-CE1 4.06Å; M249-F453 HydrophobicContact CB-CE2 4.39Å; M249-F453 HydrophobicContact CB-CG 4.14Å; M249-F453 HydrophobicContact CB-CZ 4.23Å; M249-F453 HydrophobicContact CG-CD1 3.9Å; M249-F453 HydrophobicContact CG-CD2 4.47Å; M249-F453 HydrophobicContact CG-CE1 3.44Å; M249-F453 VanDerWaalsContact CG-CE1 3.44Å; M249-F453 HydrophobicContact CG-CE2 4.05Å; M249-F453 HydrophobicContact CG-CG 4.39Å; M249-F453 HydrophobicContact CG-CZ 3.5Å; M249-F453 HydrophobicContact SD-CE1 4.06Å; M249-F453 HydrophobicContact SD-CE2 3.76Å; M249-F453 HydrophobicContact SD-CZ 3.45Å; M249-F453 WeakPolarHBondContact SD-CZ 3.24Å; N253-F453 PolarHBondContact ND2-O 3.46Å; T384-F453 WeakPolarHBondContact OG1-CD2 3.39Å; T384-F453 PolarHBondContact OG1-N 2.8Å; A385-F453 HydrophobicContact CB-CD2 3.57Å; A385-F453 HydrophobicContact CB-CE2 3.49Å; A385-F453 VanDerWaalsContact CB-CE2 3.49Å; I444-F453 WeakPolarHBondContact O-CE1 3.21Å; R451-F453 HydrophobicContact CB-CD1 4.22Å; R451-F453 HydrophobicContact CB-CD2 4.36Å; R451-F453 HydrophobicContact CB-CE1 3.7Å; R451-F453 HydrophobicContact CB-CE2 3.89Å; R451-F453 HydrophobicContact CB-CZ 3.55Å; R451-F453 HydrophobicContact CG-CE1 4.01Å; R451-F453 HydrophobicContact CG-CZ 3.82Å; F453-K455 VanDerWaalsContact C-N 3.32Å
454D98.7Very high98Very high2 Ų215.2 Ų15.21%0.0117%0.071CC..THydrogen-bonded Turntrans-78.2-12.6175.2-76.7-16.7000113.7S315 R316 R388 W391 W452S315-D454 CarbonylContact C-O 3.57Å; S315-D454 WeakPolarHBondContact CA-O 3.42Å; R316-D454 HydrophobicContact CB-CB 4.38Å; R316-D454 PolarHBondContact N-O 3.49Å; R316-D454 WeakPolarHBondContact O-CB 3.3Å; R388-D454 IonicContact CZ-OD1 2.64Å; R388-D454 IonicContact NH1-OD1 3.73Å; R388-D454 PolarHBondContact NH1-OD1 3.08Å; R388-D454 IonicContact NH2-OD1 3.37Å; R388-D454 PolarHBondContact NH2-OD1 2.93Å; R388-D454 IonicContact NH2-OD2 2.67Å; W391-D454 PolarHBondContact NE1-OD2 3.45Å; W452-D454 PolarHBondContact O-N 3.14Å; W452-D454 VanDerWaalsContact O-N 3.16Å
455K98.6Very high98Very high0 Ų015.3 Ų15.30%07%0.072CC..BIsolated β-bridgetrans-76.8143.1178.7-159.175-168.1171.50109.7T314 S315 I411 E412 A414 F417 W452 F453 F457 E472T314-K455 WeakPolarHBondContact O-CE 3.28Å; S315-K455 PolarHBondContact OG-NZ 3.02Å; I411-K455 PolarHBondContact O-NZ 2.98Å; I411-K455 VanDerWaalsContact O-NZ 3.09Å; E412-K455 PolarHBondContact O-NZ 3.33Å; A414-K455 WeakPolarHBondContact O-CE 3.46Å; A414-K455 PolarHBondContact O-NZ 3.47Å; F417-K455 HydrophobicContact CB-CB 4.11Å; F417-K455 HydrophobicContact CB-CD 4.43Å; F417-K455 HydrophobicContact CB-CG 3.88Å; W452-K455 WeakPolarHBondContact O-CB 3.39Å; W452-K455 PolarHBondContact O-N 2.94Å; F453-K455 VanDerWaalsContact C-N 3.32Å; K455-F457 WeakPolarHBondContact CG-O 3.4Å; K455-F457 PolarHBondContact O-N 2.77Å; K455-E472 WeakPolarHBondContact O-CB 3.42Å
456T97Very high97.9Very high2 Ų215.2 Ų15.21%0.0127%0.071CC..SBendtrans-47.6-40.6175.945.70000113.3R310 M311 T314 A471 E472 W475R310-T456 WeakPolarHBondContact O-CG2 3.43Å; M311-T456 PolarHBondContact O-OG1 3.37Å; T314-T456 VanDerWaalsContact CB-CG2 3.44Å; T314-T456 HydrophobicContact CG2-CG2 3.98Å; T456-A471 WeakPolarHBondContact O-CA 3.4Å; T456-E472 PolarHBondContact O-N 3.11Å; T456-E472 VanDerWaalsContact O-N 3.09Å; T456-W475 HydrophobicContact CG2-CD2 3.98Å; T456-W475 HydrophobicContact CG2-CG 3.91Å; T456-W475 PolarHBondContact O-NE1 2.99Å
457F98.3Very high97.9Very high0 Ų014.4 Ų14.40%06%0.063CC..EExtended strand (participates in β ladder)trans-153.2152.8161.265.7-85.6000112I279 M311 F312 F416 F417 K455 L469 N470 A471 L484I279-F457 HydrophobicContact CG2-CZ 4.31Å; M311-F457 HydrophobicContact CG-CE1 4.43Å; F312-F457 HydrophobicContact CD1-CE1 4.01Å; F312-F457 HydrophobicContact CD1-CZ 4.02Å; F312-F457 AromaticContact CE1-CE1 3.88Å; F312-F457 HydrophobicContact CE1-CE1 3.88Å; F312-F457 AromaticContact CE1-CZ 3.61Å; F312-F457 HydrophobicContact CE1-CZ 3.61Å; F312-F457 HydrophobicContact CZ-CZ 4.44Å; F416-F457 HydrophobicContact CB-CD2 4.2Å; F416-F457 HydrophobicContact CB-CE1 3.97Å; F416-F457 HydrophobicContact CB-CE2 3.51Å; F416-F457 HydrophobicContact CB-CZ 3.38Å; F416-F457 HydrophobicContact CD1-CZ 4.15Å; F416-F457 AromaticContact CD2-CE2 3.89Å; F416-F457 HydrophobicContact CD2-CE2 3.89Å; F416-F457 HydrophobicContact CD2-CZ 4.31Å; F416-F457 AromaticContact CG-CE2 3.75Å; F416-F457 HydrophobicContact CG-CE2 3.75Å; F416-F457 AromaticContact CG-CZ 3.72Å; F416-F457 HydrophobicContact CG-CZ 3.72Å; F417-F457 PolarHBondContact N-O 3.32Å; K455-F457 WeakPolarHBondContact CG-O 3.4Å; K455-F457 PolarHBondContact O-N 2.77Å; F457-L469 HydrophobicContact CD2-CD2 3.96Å; F457-N470 CarbonylContact C-O 3.5Å; F457-N470 WeakPolarHBondContact CA-O 3.4Å; F457-N470 VanDerWaalsContact CB-O 3.32Å; F457-N470 WeakPolarHBondContact CB-O 3.39Å; F457-A471 HydrophobicContact CB-CB 4.32Å; F457-L484 HydrophobicContact CD1-CD2 4.46Å; F457-L484 HydrophobicContact CE1-CD2 3.98Å; F457-L484 HydrophobicContact CE2-CD2 4.45Å; F457-L484 HydrophobicContact CZ-CD2 3.96Å
458T98.4Very high97.9Very high0 Ų010.7 Ų10.70%05%0.049CC..EExtended strand (participates in β ladder)trans-109.8122.1167.7-67.20000108.8F417 W452 I460 L469 N470F417-T458 HydrophobicContact CD1-CG2 3.75Å; F417-T458 CarbonylContact O-C 3.6Å; F417-T458 WeakPolarHBondContact O-CA 3.27Å; W452-T458 PolarHBondContact O-OG1 3.05Å; T458-I460 HydrophobicContact CG2-CG1 3.99Å; T458-L469 WeakPolarHBondContact O-CA 3.49Å; T458-N470 PolarHBondContact N-O 3.06Å; T458-N470 PolarHBondContact O-N 2.91Å
459L98.8Very high97.9Very high0 Ų010.7 Ų10.70%05%0.049CC..EExtended strand (participates in β ladder)trans-78.3126.8166.6170.370000108.9I275 I276 I279 F416 F417 V418 T419 V461 L469 W485I275-L459 HydrophobicContact CG1-CD1 4.48Å; I275-L459 HydrophobicContact CG2-CD1 4.22Å; I275-L459 HydrophobicContact CG2-CD2 3.56Å; I275-L459 HydrophobicContact CG2-CG 4.48Å; I276-L459 HydrophobicContact CG1-CD2 3.81Å; I279-L459 HydrophobicContact CD1-CD2 4.02Å; F416-L459 HydrophobicContact CE2-CD2 4.39Å; F417-L459 PolarHBondContact O-N 2.78Å; V418-L459 CarbonylContact C-O 3.56Å; V418-L459 VanDerWaalsContact CA-O 3.28Å; V418-L459 WeakPolarHBondContact CA-O 3.42Å; V418-L459 HydrophobicContact CG1-CD2 4.27Å; V418-L459 HydrophobicContact CG2-CB 4.34Å; V418-L459 HydrophobicContact CG2-CD2 4.21Å; T419-L459 PolarHBondContact N-O 3.46Å; L459-V461 HydrophobicContact CD1-CG2 4.36Å; L459-V461 HydrophobicContact CD2-CG2 4.15Å; L459-V461 HydrophobicContact CG-CG2 4.01Å; L459-L469 HydrophobicContact CB-CD2 4.24Å; L459-L469 HydrophobicContact CD1-CD2 4.08Å; L459-W485 HydrophobicContact CD1-CH2 4.03Å; L459-W485 HydrophobicContact CD1-CZ3 4Å
460I98.8Very high97.9Very high0 Ų09 Ų90%04%0.042CC..EExtended strand (participates in β ladder)trans-113.4126.3179.6-56158.7000107D421 L443 T458 F462 M467 G468 N470D421-I460 HydrophobicContact CB-CG2 4.48Å; L443-I460 HydrophobicContact CD2-CB 4.17Å; L443-I460 HydrophobicContact CD2-CD1 3.65Å; L443-I460 HydrophobicContact CD2-CG2 4.45Å; T458-I460 HydrophobicContact CG2-CG1 3.99Å; I460-F462 HydrophobicContact CG2-CD2 4.34Å; I460-F462 HydrophobicContact CG2-CE1 4.03Å; I460-F462 HydrophobicContact CG2-CE2 3.71Å; I460-F462 HydrophobicContact CG2-CZ 3.56Å; I460-M467 CarbonylContact O-C 2.97Å; I460-M467 WeakPolarHBondContact O-CA 2.93Å; I460-M467 WeakPolarHBondContact O-CB 3.38Å; I460-G468 PolarHBondContact N-O 2.95Å; I460-G468 PolarHBondContact O-N 3.4Å; I460-N470 HydrophobicContact CD1-CB 4.3Å
461V98.8Very high97.9Very high0 Ų09 Ų90%04%0.042CC..EExtended strand (participates in β ladder)trans-124115.1175.9-167.90000107.7Q268 R271 A272 T419 L420 D421 L459 M467Q268-V461 HydrophobicContact CG-CG1 3.99Å; Q268-V461 PolarHBondContact NE2-O 3.45Å; R271-V461 HydrophobicContact CB-CG1 4.18Å; R271-V461 HydrophobicContact CG-CG1 4.33Å; A272-V461 HydrophobicContact CB-CG1 4.38Å; A272-V461 HydrophobicContact CB-CG2 4.14Å; T419-V461 PolarHBondContact O-N 2.86Å; L420-V461 HydrophobicContact CD2-CB 4.16Å; L420-V461 HydrophobicContact CD2-CG2 4.49Å; D421-V461 PolarHBondContact N-O 3.48Å; L459-V461 HydrophobicContact CD1-CG2 4.36Å; L459-V461 HydrophobicContact CD2-CG2 4.15Å; L459-V461 HydrophobicContact CG-CG2 4.01Å; V461-M467 HydrophobicContact CG2-CB 4.46Å
462F98.6Very high98Very high0 Ų09 Ų90%04%0.042CC..  trans-79.2161.9-179.3-66.1-76.5000111.7Q268 D421 I423 Q425 Y439 S442 L443 I460 N464 G465 K466Q268-F462 WeakPolarHBondContact CG-O 3.26Å; D421-F462 HydrophobicContact CB-CD1 3.79Å; D421-F462 HydrophobicContact CB-CE1 4.07Å; I423-F462 HydrophobicContact CD1-CE1 4.37Å; I423-F462 HydrophobicContact CG1-CD1 3.93Å; I423-F462 HydrophobicContact CG1-CE1 4.09Å; I423-F462 WeakPolarHBondContact O-CB 3.29Å; Q425-F462 HydrophobicContact CB-CD1 3.78Å; Q425-F462 HydrophobicContact CB-CD2 3.94Å; Q425-F462 HydrophobicContact CB-CE1 3.84Å; Q425-F462 HydrophobicContact CB-CE2 4.01Å; Q425-F462 HydrophobicContact CB-CG 3.84Å; Q425-F462 HydrophobicContact CB-CZ 3.94Å; Q425-F462 HydrophobicContact CG-CD1 3.57Å; Q425-F462 HydrophobicContact CG-CE1 3.36Å; Q425-F462 HydrophobicContact CG-CE2 4.37Å; Q425-F462 HydrophobicContact CG-CG 4.17Å; Q425-F462 HydrophobicContact CG-CZ 3.79Å; Y439-F462 HydrophobicContact CD2-CE2 4.01Å; Y439-F462 HydrophobicContact CD2-CZ 4.4Å; Y439-F462 HydrophobicContact CE2-CD2 4.2Å; Y439-F462 AromaticContact CE2-CE2 3.65Å; Y439-F462 HydrophobicContact CE2-CE2 3.65Å; Y439-F462 HydrophobicContact CE2-CZ 4.44Å; S442-F462 WeakPolarHBondContact OG-CE1 3.04Å; S442-F462 WeakPolarHBondContact OG-CZ 3.42Å; L443-F462 HydrophobicContact CD2-CE2 3.85Å; L443-F462 HydrophobicContact CD2-CZ 4.11Å; I460-F462 HydrophobicContact CG2-CD2 4.34Å; I460-F462 HydrophobicContact CG2-CE1 4.03Å; I460-F462 HydrophobicContact CG2-CE2 3.71Å; I460-F462 HydrophobicContact CG2-CZ 3.56Å; F462-N464 WeakPolarHBondContact CB-OD1 3.34Å; F462-N464 PolarHBondContact O-N 3.5Å; F462-G465 PolarHBondContact O-N 2.86Å; F462-K466 HydrophobicContact CB-CB 4.46Å; F462-K466 WeakPolarHBondContact CB-O 3.42Å; F462-K466 HydrophobicContact CD2-CB 4.33Å; F462-K466 WeakPolarHBondContact CD2-O 3.41Å; F462-K466 PolarHBondContact N-O 3.25Å
463K98.2Very high97.9Very high116 Ų11610.9 Ų10.950%0.5045%0.051SC..THydrogen-bonded Turntrans-56.8-33.3-176.3-176.6-175.8176.2-166.10113.4D421 I423 E424 G465D421-K463 PolarHBondContact O-N 3.44Å; I423-K463 WeakPolarHBondContact O-CB 3.47Å; I423-K463 PolarHBondContact O-N 2.99Å; E424-K463 HydrophobicContact CG-CB 3.96Å; E424-K463 HydrophobicContact CG-CD 4.3Å; E424-K463 HydrophobicContact CG-CG 4.41Å; K463-G465 VanDerWaalsContact C-N 3.3Å; K463-G465 PolarHBondContact O-N 3.33Å
464N96.8Very high97.8Very high42 Ų4210.9 Ų10.923%0.2255%0.051CC..THydrogen-bonded Turntrans-86.410.5177.765.6-14.5000114.1T266 E424 Q425 F462 K466T266-N464 WeakPolarHBondContact CA-O 3.34Å; T266-N464 CarbonylContact O-C 3.5Å; E424-N464 HydrophobicContact CB-CB 4.14Å; E424-N464 HydrophobicContact CG-CB 3.84Å; Q425-N464 PolarHBondContact O-ND2 3.34Å; Q425-N464 PolarHBondContact O-OD1 3.26Å; F462-N464 WeakPolarHBondContact CB-OD1 3.34Å; F462-N464 PolarHBondContact O-N 3.5Å; N464-K466 VanDerWaalsContact C-N 3.28Å; N464-K466 PolarHBondContact O-N 3.06Å; N464-K466 PolarHBondContact OD1-N 3.37Å
465G96.6Very high97.5Very high2 Ų211.1 Ų11.12%0.0215%0.052CC..SBendtrans78.81.1179.900000115.2R271 F462 K463R271-G465 VanDerWaalsContact CD-O 3.3Å; R271-G465 WeakPolarHBondContact CD-O 3.34Å; R271-G465 WeakPolarHBondContact CG-O 3.41Å; R271-G465 PolarHBondContact NE-O 3.49Å; F462-G465 PolarHBondContact O-N 2.86Å; K463-G465 VanDerWaalsContact C-N 3.3Å; K463-G465 PolarHBondContact O-N 3.33Å
466K96.4Very high97.3Very high17 Ų1711.1 Ų11.17%0.0745%0.052CC..  trans-68.9154.6165.2-74.3-67.6-168.8178.70110F259 L260 L262 Q425 F462 N464F259-K466 PolarHBondContact O-NZ 3.2Å; L260-K466 PolarHBondContact O-NZ 2.91Å; L262-K466 PolarHBondContact O-NZ 3.26Å; Q425-K466 VanDerWaalsContact O-CB 3.3Å; Q425-K466 WeakPolarHBondContact O-CB 3.37Å; Q425-K466 VanDerWaalsContact O-CG 3.24Å; Q425-K466 WeakPolarHBondContact O-CG 3.07Å; F462-K466 HydrophobicContact CB-CB 4.46Å; F462-K466 WeakPolarHBondContact CB-O 3.42Å; F462-K466 HydrophobicContact CD2-CB 4.33Å; F462-K466 WeakPolarHBondContact CD2-O 3.41Å; F462-K466 PolarHBondContact N-O 3.25Å; N464-K466 VanDerWaalsContact C-N 3.28Å; N464-K466 PolarHBondContact O-N 3.06Å; N464-K466 PolarHBondContact OD1-N 3.37Å
467M96.8Very high97.2Very high0 Ų011.6 Ų11.60%05%0.054CC..EExtended strand (participates in β ladder)trans-145.2174.7-175.259.8-175.5176.800113.1D258 R271 I275 Y439 I460 V461 W485 M489D258-M467 HydrophobicContact CB-CG 4.1Å; D258-M467 WeakPolarHBondContact CB-O 3.5Å; D258-M467 PolarHBondContact N-O 3.15Å; D258-M467 WeakPolarHBondContact OD1-CE 3.5Å; D258-M467 WeakPolarHBondContact OD2-CG 3.16Å; R271-M467 HydrophobicContact CG-SD 4.17Å; R271-M467 VanDerWaalsContact CZ-CE 3.43Å; I275-M467 HydrophobicContact CB-SD 4.03Å; I275-M467 HydrophobicContact CD1-CE 3.44Å; I275-M467 VanDerWaalsContact CD1-CE 3.44Å; I275-M467 HydrophobicContact CD1-SD 3.65Å; I275-M467 HydrophobicContact CG1-CE 4.09Å; I275-M467 HydrophobicContact CG1-SD 3.58Å; I275-M467 VanDerWaalsContact CG1-SD 3.58Å; I275-M467 HydrophobicContact CG2-SD 4.29Å; Y439-M467 PolarHBondContact OH-O 3.03Å; I460-M467 CarbonylContact O-C 2.97Å; I460-M467 WeakPolarHBondContact O-CA 2.93Å; I460-M467 WeakPolarHBondContact O-CB 3.38Å; V461-M467 HydrophobicContact CG2-CB 4.46Å; M467-W485 HydrophobicContact CB-CH2 4.46Å; M467-W485 HydrophobicContact CE-CH2 4.29Å; M467-W485 HydrophobicContact CE-CZ2 4.49Å; M467-W485 HydrophobicContact CG-CH2 3.89Å; M467-W485 HydrophobicContact CG-CZ2 4.12Å; M467-W485 HydrophobicContact SD-CH2 4.01Å; M467-M489 HydrophobicContact CE-CG 4.03Å
468G97.5Very high97Very high0 Ų012.7 Ų12.70%06%0.063CC..EExtended strand (participates in β ladder)trans-177.2-175.1171.800000111.2A256 I460A256-G468 CarbonylContact O-C 3.58Å; A256-G468 WeakPolarHBondContact O-CA 3.47Å; I460-G468 PolarHBondContact N-O 2.95Å; I460-G468 PolarHBondContact O-N 3.4Å
469L97.8Very high96.7Very high2 Ų214.1 Ų14.11%0.017%0.073CC..EExtended strand (participates in β ladder)trans-123.6145.1179.1-59.8-178.5000111.1F255 A256 F457 T458 L459 V481 W485F255-L469 CarbonylContact C-O 3.54Å; F255-L469 WeakPolarHBondContact CA-O 3.46Å; F255-L469 VanDerWaalsContact CB-O 3.29Å; F255-L469 WeakPolarHBondContact CB-O 3.3Å; A256-L469 HydrophobicContact CB-CB 4.26Å; A256-L469 PolarHBondContact N-O 2.93Å; A256-L469 PolarHBondContact O-N 2.63Å; F457-L469 HydrophobicContact CD2-CD2 3.96Å; T458-L469 WeakPolarHBondContact O-CA 3.49Å; L459-L469 HydrophobicContact CB-CD2 4.24Å; L459-L469 HydrophobicContact CD1-CD2 4.08Å; L469-V481 HydrophobicContact CD1-CG1 3.72Å; L469-W485 HydrophobicContact CD1-CB 4.24Å; L469-W485 HydrophobicContact CD1-CD2 3.76Å; L469-W485 HydrophobicContact CD1-CE3 3.43Å; L469-W485 VanDerWaalsContact CD1-CE3 3.43Å; L469-W485 HydrophobicContact CD1-CG 4.13Å; L469-W485 HydrophobicContact CD1-CZ3 4.04Å; L469-W485 HydrophobicContact CD2-CE3 3.88Å; L469-W485 HydrophobicContact CD2-CH2 4.17Å; L469-W485 HydrophobicContact CD2-CZ3 3.57Å; L469-W485 HydrophobicContact CG-CD2 3.92Å; L469-W485 HydrophobicContact CG-CE3 3.54Å; L469-W485 HydrophobicContact CG-CH2 4.09Å; L469-W485 HydrophobicContact CG-CZ2 4.42Å; L469-W485 HydrophobicContact CG-CZ3 3.63Å
470N98.4Very high96.5Very high0 Ų014.1 Ų14.10%07%0.073CC..EExtended strand (participates in β ladder)trans-109.2137.3154.1-175.2-87.4000107.8N253 Y254 L443 I444 F457 T458 I460N253-N470 PolarHBondContact ND2-OD1 3.04Å; Y254-N470 CarbonylContact O-C 3.5Å; L443-N470 WeakPolarHBondContact O-CB 3.47Å; L443-N470 PolarHBondContact O-ND2 3.28Å; L443-N470 VanDerWaalsContact O-ND2 3.15Å; I444-N470 PolarHBondContact O-ND2 2.79Å; F457-N470 CarbonylContact C-O 3.5Å; F457-N470 WeakPolarHBondContact CA-O 3.4Å; F457-N470 VanDerWaalsContact CB-O 3.32Å; F457-N470 WeakPolarHBondContact CB-O 3.39Å; T458-N470 PolarHBondContact N-O 3.06Å; T458-N470 PolarHBondContact O-N 2.91Å; I460-N470 HydrophobicContact CD1-CB 4.3Å
471A98.1Very high96.3Very high1 Ų114.3 Ų14.31%0.0087%0.074CC..EExtended strand (participates in β ladder)trans-132.1131.4-176.900000112.4N253 Y254 T456 F457 V481N253-A471 VanDerWaalsContact CA-O 3.23Å; N253-A471 WeakPolarHBondContact CA-O 3.39Å; N253-A471 WeakPolarHBondContact CB-O 3.46Å; Y254-A471 HydrophobicContact CD2-CB 4.05Å; Y254-A471 HydrophobicContact CE1-CB 4.19Å; Y254-A471 HydrophobicContact CE2-CB 3.58Å; Y254-A471 PolarHBondContact N-O 3.38Å; Y254-A471 VanDerWaalsContact N-O 3.12Å; Y254-A471 PolarHBondContact O-N 3.5Å; T456-A471 WeakPolarHBondContact O-CA 3.4Å; F457-A471 HydrophobicContact CB-CB 4.32Å; A471-V481 HydrophobicContact CB-CG2 4.34Å
472E97.8Very high96.1Very high0 Ų015 Ų150%08%0.081CC..  trans-75.3133171.5-164.3-72.6137.400109.5I248 N253 R316 K455 T456 S474 W475I248-E472 HydrophobicContact CD1-CG 4.32Å; N253-E472 WeakPolarHBondContact OD1-CA 3.43Å; R316-E472 HydrophobicContact CB-CG 4.32Å; R316-E472 WeakPolarHBondContact CD-OE1 3.13Å; R316-E472 IonicContact NH1-OE1 3.53Å; R316-E472 PolarHBondContact NH1-OE1 3.24Å; K455-E472 WeakPolarHBondContact O-CB 3.42Å; T456-E472 PolarHBondContact O-N 3.11Å; T456-E472 VanDerWaalsContact O-N 3.09Å; E472-S474 WeakPolarHBondContact OE1-CB 3.24Å; E472-S474 PolarHBondContact OE1-N 2.67Å; E472-S474 PolarHBondContact OE1-OG 2.56Å; E472-S474 WeakPolarHBondContact OE2-CB 3.47Å; E472-S474 PolarHBondContact OE2-N 2.64Å; E472-S474 VanDerWaalsContact OE2-N 3.14Å; E472-S474 PolarHBondContact OE2-OG 3.47Å; E472-W475 PolarHBondContact O-NE1 3.14Å
473H97Very high95.9Very high45 Ų4515.1 Ų15.121%0.2088%0.081CC..SBendtrans-92.6-17.3-163.2-161.7-8.1000114.8Y241 S252 Y254 W475 A476 D477 R601Y241-H473 HydrophobicContact CD1-CB 4.4Å; Y241-H473 HydrophobicContact CE1-CB 4.07Å; Y241-H473 AromaticContact CE1-CG 3.84Å; S252-H473 VanDerWaalsContact O-CB 3.26Å; S252-H473 WeakPolarHBondContact O-CB 3.43Å; Y254-H473 HydrophobicContact CD1-CB 4.03Å; Y254-H473 AromaticContact CD1-CD2 3.86Å; Y254-H473 AromaticContact CD1-CG 3.81Å; Y254-H473 HydrophobicContact CE1-CB 3.94Å; Y254-H473 AromaticContact CE1-CG 3.68Å; Y254-H473 AromaticContact CE1-ND1 3.72Å; H473-W475 VanDerWaalsContact C-N 3.27Å; H473-W475 PolarHBondContact O-N 2.97Å; H473-A476 PolarHBondContact ND1-O 3.44Å; H473-A476 PolarHBondContact O-N 3.46Å; H473-D477 IonicContact CE1-OD1 3.86Å; H473-R601 PolarHBondContact O-NH2 3.16Å
474S95.8Very high95.7Very high0 Ų09.6 Ų9.60%06%0.057CC..SBendtrans-62.3-32.4-171.771.30000113.5Y241 L325 E472 R601Y241-S474 VanDerWaalsContact CB-CB 3.45Å; L325-S474 WeakPolarHBondContact CD2-OG 3.49Å; E472-S474 WeakPolarHBondContact OE1-CB 3.24Å; E472-S474 PolarHBondContact OE1-N 2.67Å; E472-S474 PolarHBondContact OE1-OG 2.56Å; E472-S474 WeakPolarHBondContact OE2-CB 3.47Å; E472-S474 PolarHBondContact OE2-N 2.64Å; E472-S474 VanDerWaalsContact OE2-N 3.14Å; E472-S474 PolarHBondContact OE2-OG 3.47Å; S474-R601 PolarHBondContact O-NH1 3Å
475W94Very high95.7Very high6 Ų68 Ų82%0.0235%0.048CC..SBendtrans-87.5-27.8-175.869.8-81.3000114.9Q307 R310 M311 L325 T456 E472 H473 I480 V481 R601Q307-W475 VanDerWaalsContact O-CZ3 3.29Å; Q307-W475 WeakPolarHBondContact O-CZ3 3.48Å; R310-W475 HydrophobicContact CB-CB 4.22Å; R310-W475 HydrophobicContact CB-CE3 4.15Å; M311-W475 HydrophobicContact CB-CH2 3.82Å; M311-W475 HydrophobicContact CB-CZ3 3.69Å; M311-W475 HydrophobicContact CE-CH2 4.41Å; M311-W475 HydrophobicContact CG-CH2 3.83Å; M311-W475 HydrophobicContact CG-CZ3 4.23Å; L325-W475 HydrophobicContact CD1-CB 3.88Å; L325-W475 HydrophobicContact CD2-CB 4.48Å; T456-W475 HydrophobicContact CG2-CD2 3.98Å; T456-W475 HydrophobicContact CG2-CG 3.91Å; T456-W475 PolarHBondContact O-NE1 2.99Å; E472-W475 PolarHBondContact O-NE1 3.14Å; H473-W475 VanDerWaalsContact C-N 3.27Å; H473-W475 PolarHBondContact O-N 2.97Å; W475-I480 HydrophobicContact CH2-CG2 4.43Å; W475-I480 HydrophobicContact CZ3-CG2 4.27Å; W475-V481 HydrophobicContact CH2-CG2 3.93Å; W475-V481 HydrophobicContact CZ2-CG2 3.76Å; W475-R601 PolarHBondContact O-NH1 3.1Å
476A94.3Very high95.5Very high0 Ų08.3 Ų8.30%05%0.049CC..  trans-156.3165.4-178.500000114.3Q307 H473 I480 R601Q307-A476 HydrophobicContact CB-CB 4.02Å; H473-A476 PolarHBondContact ND1-O 3.44Å; H473-A476 PolarHBondContact O-N 3.46Å; A476-I480 HydrophobicContact CB-CB 4.14Å; A476-I480 HydrophobicContact CB-CG1 4.23Å; A476-I480 HydrophobicContact CB-CG2 4.3Å; A476-R601 PolarHBondContact O-NH2 2.81Å
477D94.9Very high95.4Very high12 Ų129.2 Ų9.26%0.0646%0.055CC..  trans-95.7156176.1-49.3-47.7000111.4Q307 H473 P479 I480 R601Q307-D477 PolarHBondContact NE2-OD2 3.49Å; Q307-D477 PolarHBondContact OE1-OD2 3.26Å; H473-D477 IonicContact CE1-OD1 3.86Å; D477-P479 VanDerWaalsContact C-N 3.33Å; D477-P479 VanDerWaalsContact O-N 3.1Å; D477-I480 WeakPolarHBondContact O-CB 3.3Å; D477-I480 WeakPolarHBondContact O-CG1 3.28Å; D477-I480 PolarHBondContact O-N 3.45Å; D477-R601 IonicContact OD1-CZ 2.71Å; D477-R601 VanDerWaalsContact OD1-CZ 3.23Å; D477-R601 IonicContact OD1-NE 3.29Å; D477-R601 PolarHBondContact OD1-NE 2.95Å; D477-R601 IonicContact OD1-NH2 2.81Å; D477-R601 PolarHBondContact OD1-NH2 2.92Å; D477-R601 WeakPolarHBondContact OD2-CA 3.38Å; D477-R601 WeakPolarHBondContact OD2-CD 3.44Å; D477-R601 IonicContact OD2-NE 2.95Å; D477-R601 PolarHBondContact OD2-NE 3.39Å; D477-R601 VanDerWaalsContact OD2-NE 3.1Å
478A93.4Very high95.3Very high23 Ų239.3 Ų9.319%0.196%0.055CC..Hα-helixtrans-48.2-39.9-175.500000115.5Y254 I480 V481 G482Y254-A478 HydrophobicContact CD2-CB 4.43Å; Y254-A478 HydrophobicContact CE2-CB 4.08Å; A478-I480 PolarHBondContact O-N 3.34Å; A478-I480 VanDerWaalsContact O-N 3.08Å; A478-V481 PolarHBondContact O-N 2.99Å; A478-V481 VanDerWaalsContact O-N 3.14Å; A478-G482 PolarHBondContact O-N 2.78Å
479P92.6Very high95.1Very high31 Ų319.3 Ų9.320%0.2016%0.055CC..Hα-helixtrans-60-22.2178.6-26.736.3000115.2D477 H483 Q692D477-P479 VanDerWaalsContact C-N 3.33Å; D477-P479 VanDerWaalsContact O-N 3.1Å; P479-H483 PolarHBondContact O-N 3.4Å; P479-Q692 PolarHBondContact O-NE2 3.32Å
480I93.8Very high94.9Very high0 Ų010 Ų100%06%0.062CC..Hα-helixtrans-77.2-43.6177.7-51.7-61.9000110.5Q307 W308 M311 W475 A476 D477 A478 H483 L484Q307-I480 HydrophobicContact CB-CD1 4Å; Q307-I480 HydrophobicContact CB-CG1 3.79Å; Q307-I480 HydrophobicContact CB-CG2 4.28Å; Q307-I480 HydrophobicContact CG-CG1 4.38Å; Q307-I480 VanDerWaalsContact OE1-CG1 3.25Å; W308-I480 HydrophobicContact CD2-CG2 4.08Å; W308-I480 HydrophobicContact CE3-CD1 3.8Å; W308-I480 HydrophobicContact CE3-CG2 4.25Å; W308-I480 HydrophobicContact CH2-CD1 3.46Å; W308-I480 VanDerWaalsContact CH2-CD1 3.46Å; W308-I480 HydrophobicContact CZ2-CD1 4.28Å; W308-I480 HydrophobicContact CZ2-CG2 4.36Å; W308-I480 HydrophobicContact CZ3-CD1 3.19Å; W308-I480 HydrophobicContact CZ3-CG2 4.49Å; M311-I480 HydrophobicContact CE-CG2 3.62Å; W475-I480 HydrophobicContact CH2-CG2 4.43Å; W475-I480 HydrophobicContact CZ3-CG2 4.27Å; A476-I480 HydrophobicContact CB-CB 4.14Å; A476-I480 HydrophobicContact CB-CG1 4.23Å; A476-I480 HydrophobicContact CB-CG2 4.3Å; D477-I480 WeakPolarHBondContact O-CB 3.3Å; D477-I480 WeakPolarHBondContact O-CG1 3.28Å; D477-I480 PolarHBondContact O-N 3.45Å; A478-I480 PolarHBondContact O-N 3.34Å; A478-I480 VanDerWaalsContact O-N 3.08Å; I480-H483 PolarHBondContact O-N 3.37Å; I480-L484 PolarHBondContact O-N 3.13Å
481V94.9Very high94.8Very high3 Ų310.6 Ų10.62%0.0187%0.065CC..Hα-helixtrans-71.2-38.9175.1177.10000110.7Y254 L469 A471 W475 A478 H483 L484 W485Y254-V481 HydrophobicContact CE2-CB 4.21Å; Y254-V481 HydrophobicContact CE2-CG1 4.47Å; Y254-V481 HydrophobicContact CE2-CG2 4.3Å; Y254-V481 WeakPolarHBondContact OH-CG2 3.39Å; L469-V481 HydrophobicContact CD1-CG1 3.72Å; A471-V481 HydrophobicContact CB-CG2 4.34Å; W475-V481 HydrophobicContact CH2-CG2 3.93Å; W475-V481 HydrophobicContact CZ2-CG2 3.76Å; A478-V481 PolarHBondContact O-N 2.99Å; A478-V481 VanDerWaalsContact O-N 3.14Å; V481-H483 VanDerWaalsContact C-N 3.3Å; V481-H483 PolarHBondContact O-N 3.45Å; V481-L484 WeakPolarHBondContact O-CB 3.41Å; V481-L484 PolarHBondContact O-N 3.38Å; V481-W485 WeakPolarHBondContact O-CB 3.37Å; V481-W485 PolarHBondContact O-N 2.64Å
482G93.9Very high94.6Very high14 Ų1410.5 Ų10.514%0.1447%0.065CC..Hα-helixtrans-57.3-41.7173.300000112.3A478 L484 W485 E486A478-G482 PolarHBondContact O-N 2.78Å; G482-L484 PolarHBondContact O-N 3.48Å; G482-W485 PolarHBondContact O-N 3.19Å; G482-E486 WeakPolarHBondContact O-CG 3.29Å; G482-E486 PolarHBondContact O-N 2.67Å
483H94.4Very high94.4Very high3 Ų314.2 Ų14.21%0.0148%0.079CC..Hα-helixtrans-61.7-45.1172.7-179.3-52.3000111.8Y282 W308 P479 I480 V481 W485 N487 Q692 H693Y282-H483 AromaticContact CE2-CE1 3.67Å; Y282-H483 AromaticContact CE2-ND1 3.48Å; Y282-H483 WeakPolarHBondContact CE2-ND1 3.37Å; Y282-H483 AromaticContact CZ-CE1 3.92Å; Y282-H483 AromaticContact CZ-ND1 3.61Å; Y282-H483 PolarHBondContact OH-CE1 3.15Å; Y282-H483 VanDerWaalsContact OH-CE1 3.29Å; Y282-H483 PolarHBondContact OH-ND1 3.46Å; W308-H483 HydrophobicContact CZ2-CB 4.06Å; W308-H483 AromaticContact CZ2-CD2 3.83Å; W308-H483 AromaticContact CZ2-CG 3.85Å; P479-H483 PolarHBondContact O-N 3.4Å; I480-H483 PolarHBondContact O-N 3.37Å; V481-H483 VanDerWaalsContact C-N 3.3Å; V481-H483 PolarHBondContact O-N 3.45Å; H483-W485 VanDerWaalsContact C-N 3.31Å; H483-W485 PolarHBondContact O-N 3.17Å; H483-N487 PolarHBondContact CE1-ND2 2.64Å; H483-N487 PolarHBondContact ND1-ND2 3.44Å; H483-N487 PolarHBondContact O-N 3.48Å; H483-N487 PolarHBondContact O-ND2 3.35Å; H483-Q692 PolarHBondContact CD2-OE1 3.24Å; H483-H693 AromaticContact CD2-CE1 3.53Å; H483-H693 AromaticContact CD2-NE2 3.53Å; H483-H693 AromaticContact CE1-CE1 3.4Å; H483-H693 PolarHBondContact CE1-CE1 2.95Å; H483-H693 VanDerWaalsContact CE1-CE1 3.4Å; H483-H693 AromaticContact NE2-CE1 3Å; H483-H693 PolarHBondContact NE2-CE1 3.47Å; H483-H693 AromaticContact NE2-NE2 3.37Å; H483-H693 PolarHBondContact NE2-NE2 2.86Å
484L95.4Very high94.2Very high1 Ų116.6 Ų16.61%0.0059%0.093CC..Hα-helixtrans-55.8-51.6174.2168.268.1000110.1Y282 M311 F312 F457 I480 V481 G482 N487 V488Y282-L484 HydrophobicContact CD1-CD1 3.33Å; Y282-L484 HydrophobicContact CD2-CD1 4.02Å; Y282-L484 HydrophobicContact CE1-CB 4.34Å; Y282-L484 HydrophobicContact CE1-CD1 3.71Å; Y282-L484 HydrophobicContact CE2-CD1 4.33Å; Y282-L484 HydrophobicContact CG-CD1 3.5Å; Y282-L484 VanDerWaalsContact CG-CD1 3.5Å; M311-L484 HydrophobicContact CE-CB 4.12Å; M311-L484 HydrophobicContact CG-CD2 4.42Å; M311-L484 HydrophobicContact SD-CB 4.04Å; M311-L484 HydrophobicContact SD-CD1 4.2Å; M311-L484 HydrophobicContact SD-CD2 3.99Å; M311-L484 HydrophobicContact SD-CG 4.31Å; F312-L484 HydrophobicContact CZ-CD1 3.97Å; F312-L484 HydrophobicContact CZ-CD2 4.39Å; F457-L484 HydrophobicContact CD1-CD2 4.46Å; F457-L484 HydrophobicContact CE1-CD2 3.98Å; F457-L484 HydrophobicContact CE2-CD2 4.45Å; F457-L484 HydrophobicContact CZ-CD2 3.96Å; I480-L484 PolarHBondContact O-N 3.13Å; V481-L484 WeakPolarHBondContact O-CB 3.41Å; V481-L484 PolarHBondContact O-N 3.38Å; G482-L484 PolarHBondContact O-N 3.48Å; L484-N487 PolarHBondContact O-N 3.47Å; L484-V488 HydrophobicContact CD1-CG2 3.67Å; L484-V488 HydrophobicContact CG-CG2 4.3Å; L484-V488 WeakPolarHBondContact O-CB 3.41Å; L484-V488 VanDerWaalsContact O-CG2 3.24Å; L484-V488 WeakPolarHBondContact O-CG2 3.42Å; L484-V488 PolarHBondContact O-N 2.94Å
485W95.1Very high94.1Very high7 Ų722.5 Ų22.53%0.02712%0.12CC..Hα-helixtrans-62.4-49.3-171.6-164.3-128000112.7M257 L459 M467 L469 V481 G482 H483 N487 V488 M489M257-W485 PolarHBondContact O-NE1 3Å; L459-W485 HydrophobicContact CD1-CH2 4.03Å; L459-W485 HydrophobicContact CD1-CZ3 4Å; M467-W485 HydrophobicContact CB-CH2 4.46Å; M467-W485 HydrophobicContact CE-CH2 4.29Å; M467-W485 HydrophobicContact CE-CZ2 4.49Å; M467-W485 HydrophobicContact CG-CH2 3.89Å; M467-W485 HydrophobicContact CG-CZ2 4.12Å; M467-W485 HydrophobicContact SD-CH2 4.01Å; L469-W485 HydrophobicContact CD1-CB 4.24Å; L469-W485 HydrophobicContact CD1-CD2 3.76Å; L469-W485 HydrophobicContact CD1-CE3 3.43Å; L469-W485 VanDerWaalsContact CD1-CE3 3.43Å; L469-W485 HydrophobicContact CD1-CG 4.13Å; L469-W485 HydrophobicContact CD1-CZ3 4.04Å; L469-W485 HydrophobicContact CD2-CE3 3.88Å; L469-W485 HydrophobicContact CD2-CH2 4.17Å; L469-W485 HydrophobicContact CD2-CZ3 3.57Å; L469-W485 HydrophobicContact CG-CD2 3.92Å; L469-W485 HydrophobicContact CG-CE3 3.54Å; L469-W485 HydrophobicContact CG-CH2 4.09Å; L469-W485 HydrophobicContact CG-CZ2 4.42Å; L469-W485 HydrophobicContact CG-CZ3 3.63Å; V481-W485 WeakPolarHBondContact O-CB 3.37Å; V481-W485 PolarHBondContact O-N 2.64Å; G482-W485 PolarHBondContact O-N 3.19Å; H483-W485 VanDerWaalsContact C-N 3.31Å; H483-W485 PolarHBondContact O-N 3.17Å; W485-N487 PolarHBondContact O-N 3.27Å; W485-V488 PolarHBondContact O-N 2.95Å; W485-M489 HydrophobicContact CD2-CE 4.4Å; W485-M489 HydrophobicContact CD2-CG 4.24Å; W485-M489 HydrophobicContact CD2-SD 4.24Å; W485-M489 HydrophobicContact CG-CE 3.96Å; W485-M489 HydrophobicContact CG-SD 4.41Å; W485-M489 HydrophobicContact CZ2-CG 4.33Å; W485-M489 HydrophobicContact CZ2-SD 3.98Å; W485-M489 PolarHBondContact NE1-SD 2.97Å; W485-M489 VanDerWaalsContact NE1-SD 3.4Å; W485-M489 WeakPolarHBondContact O-CG 3.33Å; W485-M489 PolarHBondContact O-N 3.48Å
486E92.8Very high94.3Very high9 Ų923.7 Ų23.74%0.04213%0.127CC..Hα-helixtrans-59.2-44.2177-74.9179.3-141.600112.8G482 V488 A490 Q691 Q692 H693 I694G482-E486 WeakPolarHBondContact O-CG 3.29Å; G482-E486 PolarHBondContact O-N 2.67Å; E486-V488 VanDerWaalsContact C-N 3.33Å; E486-V488 PolarHBondContact O-N 3.09Å; E486-A490 WeakPolarHBondContact O-CB 3.48Å; E486-A490 PolarHBondContact O-N 2.96Å; E486-Q691 VanDerWaalsContact OE1-CA 3.23Å; E486-Q691 WeakPolarHBondContact OE1-CA 3.46Å; E486-Q692 PolarHBondContact OE1-N 3.35Å; E486-Q692 PolarHBondContact OE2-N 3.05Å; E486-H693 PolarHBondContact OE2-N 3.13Å; E486-I694 HydrophobicContact CB-CD1 4.19Å; E486-I694 HydrophobicContact CB-CG1 4.36Å; E486-I694 HydrophobicContact CG-CD1 4.25Å
487N93.9Very high94.3Very high37 Ų3724.1 Ų24.120%0.19813%0.131CC..Hα-helixtrans-67.1-39.1-179.3-77-101.7000111.2Y282 H483 L484 W485 T491 H693Y282-N487 HydrophobicContact CD2-CB 3.84Å; Y282-N487 HydrophobicContact CE2-CB 3.94Å; H483-N487 PolarHBondContact CE1-ND2 2.64Å; H483-N487 PolarHBondContact ND1-ND2 3.44Å; H483-N487 PolarHBondContact O-N 3.48Å; H483-N487 PolarHBondContact O-ND2 3.35Å; L484-N487 PolarHBondContact O-N 3.47Å; W485-N487 PolarHBondContact O-N 3.27Å; N487-T491 VanDerWaalsContact O-CB 3.31Å; N487-T491 WeakPolarHBondContact O-CB 3.32Å; N487-T491 PolarHBondContact O-N 2.71Å; N487-T491 PolarHBondContact O-OG1 3.13Å; N487-H693 VanDerWaalsContact CG-ND1 3.32Å; N487-H693 PolarHBondContact ND2-CE1 3.32Å; N487-H693 PolarHBondContact ND2-ND1 3.48Å; N487-H693 PolarHBondContact OD1-ND1 3.03Å
488V95.4Very high94.4Very high1 Ų124.6 Ų24.61%0.00613%0.133CC..Hα-helixtrans-68.7-48.2-177.91610000110.8I275 A278 I279 L484 W485 E486 A490 T491 E492I275-V488 HydrophobicContact CD1-CG1 3.32Å; I275-V488 HydrophobicContact CG1-CG1 3.69Å; A278-V488 HydrophobicContact CB-CG1 4.05Å; I279-V488 HydrophobicContact CB-CG2 4.42Å; I279-V488 HydrophobicContact CD1-CG1 4.48Å; I279-V488 HydrophobicContact CG1-CB 4.38Å; I279-V488 HydrophobicContact CG1-CG1 3.65Å; I279-V488 HydrophobicContact CG1-CG2 3.82Å; L484-V488 HydrophobicContact CD1-CG2 3.67Å; L484-V488 HydrophobicContact CG-CG2 4.3Å; L484-V488 WeakPolarHBondContact O-CB 3.41Å; L484-V488 VanDerWaalsContact O-CG2 3.24Å; L484-V488 WeakPolarHBondContact O-CG2 3.42Å; L484-V488 PolarHBondContact O-N 2.94Å; W485-V488 PolarHBondContact O-N 2.95Å; E486-V488 VanDerWaalsContact C-N 3.33Å; E486-V488 PolarHBondContact O-N 3.09Å; V488-A490 VanDerWaalsContact C-N 3.32Å; V488-A490 PolarHBondContact O-N 3.34Å; V488-T491 PolarHBondContact O-N 2.82Å; V488-E492 WeakPolarHBondContact O-CB 3.38Å; V488-E492 PolarHBondContact O-N 3.5Å
489M94.3Very high94.6Very high0 Ų025.7 Ų25.70%014%0.139CC..Hα-helixtrans-63.4-38.2176.2-66.3-170.7-64.600111.8F259 M467 W485 Y493F259-M489 HydrophobicContact CD1-CE 4.46Å; F259-M489 HydrophobicContact CD1-SD 4.4Å; F259-M489 HydrophobicContact CD2-SD 4.47Å; F259-M489 HydrophobicContact CE1-CB 4.26Å; F259-M489 HydrophobicContact CE1-CE 4.02Å; F259-M489 HydrophobicContact CE1-SD 4.22Å; F259-M489 HydrophobicContact CE2-CB 3.69Å; F259-M489 HydrophobicContact CE2-CG 4.44Å; F259-M489 HydrophobicContact CE2-SD 4.34Å; F259-M489 HydrophobicContact CZ-CB 3.47Å; F259-M489 VanDerWaalsContact CZ-CB 3.47Å; F259-M489 HydrophobicContact CZ-CE 4.34Å; F259-M489 HydrophobicContact CZ-CG 4.39Å; F259-M489 HydrophobicContact CZ-SD 4.21Å; M467-M489 HydrophobicContact CE-CG 4.03Å; W485-M489 HydrophobicContact CD2-CE 4.4Å; W485-M489 HydrophobicContact CD2-CG 4.24Å; W485-M489 HydrophobicContact CD2-SD 4.24Å; W485-M489 HydrophobicContact CG-CE 3.96Å; W485-M489 HydrophobicContact CG-SD 4.41Å; W485-M489 HydrophobicContact CZ2-CG 4.33Å; W485-M489 HydrophobicContact CZ2-SD 3.98Å; W485-M489 PolarHBondContact NE1-SD 2.97Å; W485-M489 VanDerWaalsContact NE1-SD 3.4Å; W485-M489 WeakPolarHBondContact O-CG 3.33Å; W485-M489 PolarHBondContact O-N 3.48Å; M489-Y493 PolarHBondContact O-N 3.12Å; M489-Y493 VanDerWaalsContact O-N 3.13Å
490A93.3Very high94.7Very high18 Ų1834.3 Ų34.315%0.14918%0.176CC..Hα-helixtrans-68.2-46.5176.500000113.1E486 V488 E492 Y493 L494 I694 M702E486-A490 WeakPolarHBondContact O-CB 3.48Å; E486-A490 PolarHBondContact O-N 2.96Å; V488-A490 VanDerWaalsContact C-N 3.32Å; V488-A490 PolarHBondContact O-N 3.34Å; A490-E492 VanDerWaalsContact C-N 3.31Å; A490-E492 PolarHBondContact O-N 2.95Å; A490-Y493 PolarHBondContact O-N 3.28Å; A490-L494 HydrophobicContact CB-CD1 4.4Å; A490-L494 VanDerWaalsContact O-CB 3.24Å; A490-L494 WeakPolarHBondContact O-CB 3.43Å; A490-L494 WeakPolarHBondContact O-CG 3.24Å; A490-L494 PolarHBondContact O-N 2.84Å; A490-I694 HydrophobicContact CB-CG1 4.3Å; A490-M702 HydrophobicContact CB-CE 3.73Å
491T95.3Very high94.8Very high11 Ų1139.1 Ų39.17%0.06720%0.202CC..Hα-helixtrans-62.2-40.2177.1-740000111.2A278 L281 N487 V488 E495 L496A278-T491 HydrophobicContact CB-CG2 4.15Å; L281-T491 HydrophobicContact CD1-CG2 4.22Å; N487-T491 VanDerWaalsContact O-CB 3.31Å; N487-T491 WeakPolarHBondContact O-CB 3.32Å; N487-T491 PolarHBondContact O-N 2.71Å; N487-T491 PolarHBondContact O-OG1 3.13Å; V488-T491 PolarHBondContact O-N 2.82Å; T491-E495 HydrophobicContact CG2-CB 4.34Å; T491-E495 WeakPolarHBondContact O-CA 3.33Å; T491-E495 VanDerWaalsContact O-CB 3.24Å; T491-E495 WeakPolarHBondContact O-CB 3.46Å; T491-E495 PolarHBondContact O-N 3.42Å; T491-E495 PolarHBondContact OG1-OE1 3.1Å; T491-L496 HydrophobicContact CG2-CG 4.41Å; T491-L496 PolarHBondContact O-N 3.05Å
492E95.1Very high94.9Very high0 Ų039.7 Ų39.70%021%0.208CC..Iπ-helixtrans-57.8-55.5174.8171-170.9-141.500112R271 N274 I275 V488 A490 L496 G497 Y498R271-E492 IonicContact CZ-OE1 2.66Å; R271-E492 IonicContact CZ-OE2 3.28Å; R271-E492 IonicContact NE-OE1 3.83Å; R271-E492 IonicContact NH1-OE1 3.58Å; R271-E492 PolarHBondContact NH1-OE1 3.08Å; R271-E492 IonicContact NH1-OE2 2.99Å; R271-E492 PolarHBondContact NH1-OE2 3.29Å; R271-E492 IonicContact NH2-OE2 2.67Å; R271-E492 PolarHBondContact NH2-OE2 2.91Å; N274-E492 HydrophobicContact CB-CG 4.09Å; I275-E492 HydrophobicContact CD1-CB 4.28Å; V488-E492 WeakPolarHBondContact O-CB 3.38Å; V488-E492 PolarHBondContact O-N 3.5Å; A490-E492 VanDerWaalsContact C-N 3.31Å; A490-E492 PolarHBondContact O-N 2.95Å; E492-L496 PolarHBondContact O-N 2.87Å; E492-G497 PolarHBondContact O-N 3.49Å; E492-Y498 HydrophobicContact CG-CE2 4.29Å; E492-Y498 PolarHBondContact OE1-OH 2.87Å
493Y92Very high95.1Very high78 Ų7841.4 Ų41.431%0.30621%0.212SC..Iπ-helixtrans-73-43.9-172.3-179.7-111.6000112.3L262 P264 M489 A490 E701 M702L262-Y493 HydrophobicContact CD1-CE2 3.81Å; L262-Y493 HydrophobicContact CD2-CD1 4.09Å; L262-Y493 HydrophobicContact CD2-CD2 3.77Å; L262-Y493 HydrophobicContact CD2-CE1 4.03Å; L262-Y493 HydrophobicContact CD2-CE2 3.71Å; L262-Y493 HydrophobicContact CD2-CG 3.94Å; L262-Y493 HydrophobicContact CG-CD2 4.49Å; L262-Y493 HydrophobicContact CG-CE2 4.25Å; P264-Y493 HydrophobicContact CB-CD2 4.3Å; P264-Y493 HydrophobicContact CG-CD2 3.82Å; P264-Y493 HydrophobicContact CG-CE2 4.44Å; M489-Y493 PolarHBondContact O-N 3.12Å; M489-Y493 VanDerWaalsContact O-N 3.13Å; A490-Y493 PolarHBondContact O-N 3.28Å; Y493-E701 HydrophobicContact CE1-CG 4.4Å; Y493-E701 WeakPolarHBondContact CE1-OE1 3.44Å; Y493-E701 PolarHBondContact OH-OE1 3.34Å; Y493-M702 HydrophobicContact CD1-CE 4.39Å; Y493-M702 HydrophobicContact CD1-CG 4.05Å; Y493-M702 HydrophobicContact CD1-SD 3.78Å; Y493-M702 HydrophobicContact CE1-CG 4.23Å; Y493-M702 HydrophobicContact CE1-SD 4.26Å
494L92.8Very high95.2Very high94 Ų9441.3 Ų41.349%0.49221%0.212SC..Iπ-helixtrans-88.6-26.8-172.3-58.5175000113.9A490 M702A490-L494 HydrophobicContact CB-CD1 4.4Å; A490-L494 VanDerWaalsContact O-CB 3.24Å; A490-L494 WeakPolarHBondContact O-CB 3.43Å; A490-L494 WeakPolarHBondContact O-CG 3.24Å; A490-L494 PolarHBondContact O-N 2.84Å; L494-M702 HydrophobicContact CD1-CE 4.24Å; L494-M702 HydrophobicContact CD1-SD 4.11Å; L494-M702 HydrophobicContact CD2-SD 4.07Å; L494-M702 HydrophobicContact CG-CE 4.35Å; L494-M702 HydrophobicContact CG-SD 4.13Å
495E95.1Very high95.3Very high124 Ų12448.4 Ų48.458%0.57924%0.239SC*.Iπ-helixtrans-112-47.3-174.5-53.5174.1-139.400112.8T491T491-E495 HydrophobicContact CG2-CB 4.34Å; T491-E495 WeakPolarHBondContact O-CA 3.33Å; T491-E495 VanDerWaalsContact O-CB 3.24Å; T491-E495 WeakPolarHBondContact O-CB 3.46Å; T491-E495 PolarHBondContact O-N 3.42Å; T491-E495 PolarHBondContact OG1-OE1 3.1Å
496L96.8Very high95.3Very high31 Ų3150.4 Ų50.416%0.16226%0.262CS..Iπ-helixtrans-81.4-55.2-174.5-59.1-179.5000111.8N274 H277 A278 P356 T491 E492 R505N274-L496 HydrophobicContact CB-CD1 4.35Å; N274-L496 WeakPolarHBondContact O-CD1 3.44Å; H277-L496 HydrophobicContact CB-CD1 4.42Å; A278-L496 HydrophobicContact CB-CD1 4.1Å; P356-L496 HydrophobicContact CG-CD1 4.49Å; P356-L496 HydrophobicContact CG-CD2 4.46Å; T491-L496 HydrophobicContact CG2-CG 4.41Å; T491-L496 PolarHBondContact O-N 3.05Å; E492-L496 PolarHBondContact O-N 2.87Å; L496-R505 WeakPolarHBondContact O-CD 3.4Å
497G95.1Very high95.4Very high9 Ų956 Ų569%0.09329%0.292CS..  trans61.1-176.2-179.700000114.6N274 E492N274-G497 PolarHBondContact ND2-O 3.04Å; E492-G497 PolarHBondContact O-N 3.49Å
498Y97.5Very high95.3Very high23 Ų2357.8 Ų57.89%0.0930%0.304CS..BIsolated β-bridgetrans-126.8162.5-177.4-63.4-88.5000110.2P264 T265 A270 R271 N274 E492 G502 H503 R505P264-Y498 HydrophobicContact CB-CD2 3.8Å; P264-Y498 HydrophobicContact CB-CE2 3.46Å; P264-Y498 VanDerWaalsContact CB-CE2 3.46Å; T265-Y498 HydrophobicContact CG2-CD1 3.85Å; T265-Y498 HydrophobicContact CG2-CE1 3.36Å; T265-Y498 HydrophobicContact CG2-CE2 4.3Å; T265-Y498 HydrophobicContact CG2-CG 4.48Å; A270-Y498 HydrophobicContact CB-CD1 4.36Å; A270-Y498 HydrophobicContact CB-CE1 4.09Å; R271-Y498 WeakPolarHBondContact CA-OH 3.47Å; N274-Y498 HydrophobicContact CB-CE1 4.23Å; N274-Y498 WeakPolarHBondContact CB-OH 3.35Å; N274-Y498 WeakPolarHBondContact ND2-CE1 3.23Å; N274-Y498 PolarHBondContact ND2-OH 3.18Å; E492-Y498 HydrophobicContact CG-CE2 4.29Å; E492-Y498 PolarHBondContact OE1-OH 2.87Å; Y498-G502 WeakPolarHBondContact CD1-O 3.36Å; Y498-H503 CarbonylContact C-O 3.53Å; Y498-H503 VanDerWaalsContact CA-O 3.29Å; Y498-H503 WeakPolarHBondContact CA-O 3.39Å; Y498-H503 WeakPolarHBondContact CB-O 3.45Å; Y498-R505 PolarHBondContact O-NE 2.81Å; Y498-R505 PolarHBondContact O-NH2 2.86Å
499S96.8Very high95.1Very high46 Ų4659.3 Ų59.332%0.32231%0.313SS..  trans-80.2171.2166.741.70000111.1D501 G502 H503S499-D501 VanDerWaalsContact CB-OD1 3.23Å; S499-D501 WeakPolarHBondContact CB-OD1 3.45Å; S499-D501 PolarHBondContact O-N 3.17Å; S499-D501 PolarHBondContact OG-OD1 3.22Å; S499-G502 PolarHBondContact O-N 3.06Å; S499-H503 PolarHBondContact N-O 2.64Å; S499-H503 PolarHBondContact OG-N 3.3Å; S499-H503 PolarHBondContact OG-O 2.82Å; S499-H503 VanDerWaalsContact OG-O 3.05Å
500E94.9Very high95Very high212 Ų21265.5 Ų65.599%0.99134%0.341SS*.THydrogen-bonded Turntrans-61.2-29.4-178-65.3-176.8170.700113.2G502E500-G502 PolarHBondContact O-N 3.26Å
501D95.6Very high94.8Very high101 Ų10171 Ų7154%0.5437%0.368SS..THydrogen-bonded Turntrans-82.65.3174.560.61.1000113.6S499 H503S499-D501 VanDerWaalsContact CB-OD1 3.23Å; S499-D501 WeakPolarHBondContact CB-OD1 3.45Å; S499-D501 PolarHBondContact O-N 3.17Å; S499-D501 PolarHBondContact OG-OD1 3.22Å; D501-H503 VanDerWaalsContact C-N 3.32Å; D501-H503 PolarHBondContact O-N 3.11Å; D501-H503 IonicContact OD1-CD2 3.3Å; D501-H503 IonicContact OD1-CG 2.77Å; D501-H503 PolarHBondContact OD1-N 3.47Å; D501-H503 IonicContact OD2-CD2 3.75Å; D501-H503 PolarHBondContact OD2-CD2 3.36Å
502G96.6Very high94.6Very high14 Ų1470.7 Ų70.714%0.14437%0.366CS..SBendtrans82.41.8175.700000115.2T265 A270 Y498 S499 E500T265-G502 WeakPolarHBondContact CB-O 3.42Å; T265-G502 PolarHBondContact OG1-O 3.15Å; A270-G502 WeakPolarHBondContact CB-O 3.23Å; Y498-G502 WeakPolarHBondContact CD1-O 3.36Å; S499-G502 PolarHBondContact O-N 3.06Å; E500-G502 PolarHBondContact O-N 3.26Å
503H98.4Very high94.3Very high50 Ų5073.1 Ų73.123%0.23138%0.382CS..PPolyproline II helixtrans-79.7163.2178.1-75.4-56.8000113.1L267 R357 E360 Y498 S499 D501L267-H503 WeakPolarHBondContact CD1-ND1 3.18Å; R357-H503 PolarHBondContact NH1-ND1 2.8Å; E360-H503 IonicContact OE1-CE1 3.22Å; E360-H503 IonicContact OE1-CG 3.54Å; E360-H503 IonicContact OE1-ND1 3.93Å; E360-H503 PolarHBondContact OE1-ND1 2.81Å; Y498-H503 CarbonylContact C-O 3.53Å; Y498-H503 VanDerWaalsContact CA-O 3.29Å; Y498-H503 WeakPolarHBondContact CA-O 3.39Å; Y498-H503 WeakPolarHBondContact CB-O 3.45Å; S499-H503 PolarHBondContact N-O 2.64Å; S499-H503 PolarHBondContact OG-N 3.3Å; S499-H503 PolarHBondContact OG-O 2.82Å; S499-H503 VanDerWaalsContact OG-O 3.05Å; D501-H503 VanDerWaalsContact C-N 3.32Å; D501-H503 PolarHBondContact O-N 3.11Å; D501-H503 IonicContact OD1-CD2 3.3Å; D501-H503 IonicContact OD1-CG 2.77Å; D501-H503 PolarHBondContact OD1-N 3.47Å; D501-H503 IonicContact OD2-CD2 3.75Å; D501-H503 PolarHBondContact OD2-CD2 3.36Å
504C98.2Very high94.4Very high2 Ų273.5 Ų73.51%0.01439%0.388CS..BIsolated β-bridgetrans-64.8140.7171.2-71.80000110.7A270 N274 P356 R357 E360A270-C504 PolarHBondContact O-SG 3.03Å; N274-C504 VanDerWaalsContact CG-SG 3.57Å; P356-C504 HydrophobicContact CB-CB 3.78Å; R357-C504 HydrophobicContact CB-CB 4.24Å; R357-C504 WeakPolarHBondContact CD-O 3.34Å; E360-C504 VanDerWaalsContact OE2-CB 3.25Å; E360-C504 WeakPolarHBondContact OE2-CB 3.41Å; E360-C504 PolarHBondContact OE2-N 3.3Å
505R97.3Very high94.6Very high149 Ų14970 Ų7056%0.56237%0.371SS*.SBendtrans-64.4143.8174.9-62.4-177.7-178.3167.3-5.7111.9L496 Y498L496-R505 WeakPolarHBondContact O-CD 3.4Å; Y498-R505 PolarHBondContact O-NE 2.81Å; Y498-R505 PolarHBondContact O-NH2 2.86Å
506G94.8Very high94.8Very high49 Ų4967.1 Ų67.151%0.50536%0.362SS..SBendtrans106.7-173.9179.400000113.1R357R357-G506 WeakPolarHBondContact CG-O 3.47Å
507D93.5Very high94.8Very high127 Ų12767.4 Ų67.468%0.67936%0.362SS*.  trans-104151.7-173.7-49.4-64.3000112.7
508T92.4Very high95Very high74 Ų7467.6 Ų67.645%0.45436%0.361SS..  trans-71.7158.9169.456.90000111.4R357R357-T508 HydrophobicContact CG-CG2 4Å
509N92.2Very high95Very high34 Ų3469.9 Ų69.918%0.18237%0.372CS..  trans-139.6113.3177.4177.73000110.2E358 Q361 N511 I512E358-N509 HydrophobicContact CG-CB 4.03Å; E358-N509 WeakPolarHBondContact OE1-CB 3.34Å; E358-N509 PolarHBondContact OE1-ND2 2.75Å; Q361-N509 VanDerWaalsContact OE1-N 3.15Å; Q361-N509 PolarHBondContact OE1-O 3.28Å; N509-N511 PolarHBondContact O-N 2.91Å; N509-N511 WeakPolarHBondContact OD1-CB 3.18Å; N509-N511 PolarHBondContact OD1-N 3.09Å; N509-I512 HydrophobicContact CB-CG2 3.89Å; N509-I512 WeakPolarHBondContact ND2-CG2 3.34Å; N509-I512 VanDerWaalsContact O-CG1 3.31Å; N509-I512 WeakPolarHBondContact O-CG1 3.49Å
510Q90.9Very high95.1Very high130 Ų13068.1 Ų68.161%0.60736%0.359SS*.THydrogen-bonded Turntrans-72.4-17-176.7-61.4-60.6-12.400113.6I512Q510-I512 VanDerWaalsContact C-N 3.32Å; Q510-I512 PolarHBondContact O-N 3.13Å
511N89.6Confident95.2Very high133 Ų13363 Ų6371%0.71134%0.335SS*.THydrogen-bonded Turntrans-85-3.6-177.1-61.3-28.6000113.5H349 N509H349-N511 PolarHBondContact CE1-O 2.75Å; N509-N511 PolarHBondContact O-N 2.91Å; N509-N511 WeakPolarHBondContact OD1-CB 3.18Å; N509-N511 PolarHBondContact OD1-N 3.09Å
512I92.1Very high95.3Very high4 Ų458.8 Ų58.82%0.02131%0.312CS..SBendtrans-69.2144.3177.469.3-172.1000110.8L354 E358 Q362 N509 Q510 I514L354-I512 HydrophobicContact CD2-CB 4.33Å; L354-I512 HydrophobicContact CD2-CG2 3.9Å; E358-I512 HydrophobicContact CB-CD1 3.93Å; E358-I512 HydrophobicContact CG-CG2 4.42Å; Q362-I512 HydrophobicContact CG-CD1 3.87Å; N509-I512 HydrophobicContact CB-CG2 3.89Å; N509-I512 WeakPolarHBondContact ND2-CG2 3.34Å; N509-I512 VanDerWaalsContact O-CG1 3.31Å; N509-I512 WeakPolarHBondContact O-CG1 3.49Å; Q510-I512 VanDerWaalsContact C-N 3.32Å; Q510-I512 PolarHBondContact O-N 3.13Å; I512-I514 PolarHBondContact O-N 3.27Å
513P87.7Confident95.3Very high52 Ų5260.4 Ų60.434%0.33832%0.32SS..PPolyproline II helixtrans-57.2132.4177.1-22.332.3000110.8Q362Q362-P513 PolarHBondContact NE2-O 2.9Å; Q362-P513 PolarHBondContact OE1-O 3.1Å
514I94.3Very high95.3Very high85 Ų8565.1 Ų65.144%0.43634%0.342SS..PPolyproline II helixtrans-69.5154.3175.960174.6000111.5I512 T516I512-I514 PolarHBondContact O-N 3.27Å; I514-T516 PolarHBondContact O-N 3Å
515P97.7Very high95.3Very high20 Ų2070.3 Ų70.313%0.1337%0.366CS..PPolyproline II helixtrans-57134.9170.9-2436.8000111F343 V345 Q362 R365 I366F343-P515 HydrophobicContact CB-CB 4.23Å; F343-P515 HydrophobicContact CD1-CB 4.3Å; V345-P515 HydrophobicContact CG2-CB 4.08Å; V345-P515 HydrophobicContact CG2-CG 4.38Å; Q362-P515 HydrophobicContact CB-CG 4.21Å; R365-P515 HydrophobicContact CB-CG 4.36Å; I366-P515 HydrophobicContact CD1-CB 3.97Å; I366-P515 HydrophobicContact CD1-CG 4.05Å; I366-P515 HydrophobicContact CG1-CB 3.83Å; I366-P515 HydrophobicContact CG1-CG 3.85Å
516T97.8Very high95.4Very high64 Ų6463.2 Ų63.239%0.39334%0.34SS..EExtended strand (participates in β ladder)trans-101.2113.8178.8-48.10000109.6F343 K344 I514 L518F343-T516 CarbonylContact C-O 3.35Å; F343-T516 WeakPolarHBondContact CA-O 3.23Å; K344-T516 PolarHBondContact N-O 3.26Å; K344-T516 PolarHBondContact O-N 2.7Å; I514-T516 PolarHBondContact O-N 3Å; T516-L518 PolarHBondContact O-N 3.26Å
517K98.2Very high95.5Very high37 Ų3763.5 Ų63.516%0.16133%0.328CS..EExtended strand (participates in β ladder)trans-62.2126.1173.1-171.6177.6179.4178.60110Y342 F343 S371 E372 Q519Y342-K517 WeakPolarHBondContact O-CA 3.47Å; F343-K517 HydrophobicContact CD1-CB 3.96Å; F343-K517 HydrophobicContact CD1-CG 4.44Å; F343-K517 HydrophobicContact CE1-CB 3.84Å; F343-K517 HydrophobicContact CE1-CD 4.46Å; F343-K517 HydrophobicContact CE1-CG 4.08Å; F343-K517 HydrophobicContact CZ-CG 4.47Å; S371-K517 PolarHBondContact OG-NZ 2.78Å; E372-K517 PolarHBondContact O-NZ 3.24Å; K517-Q519 PolarHBondContact O-NE2 2.98Å; K517-Q519 VanDerWaalsContact O-NE2 3.08Å
518L98.4Very high95.8Very high13 Ų1364.1 Ų64.17%0.06833%0.327CS..  trans-67.6148.9176.3-61.9-170.2000110.2V335 Y342 K344 Q374 A410 I411 T516 W520V335-L518 HydrophobicContact CG1-CD1 4.23Å; V335-L518 HydrophobicContact CG2-CD1 4.46Å; Y342-L518 PolarHBondContact O-N 2.68Å; K344-L518 HydrophobicContact CB-CD2 3.93Å; Q374-L518 PolarHBondContact NE2-O 3.04Å; A410-L518 HydrophobicContact CB-CD1 4.36Å; A410-L518 HydrophobicContact CB-CD2 4.01Å; I411-L518 HydrophobicContact CD1-CD1 4.25Å; I411-L518 HydrophobicContact CG1-CD1 3.96Å; T516-L518 PolarHBondContact O-N 3.26Å; L518-W520 HydrophobicContact CB-CZ2 4.33Å; L518-W520 HydrophobicContact CD1-CZ2 4.17Å
519Q98Very high96.1Very high71 Ų7162.5 Ų62.533%0.33232%0.317SS..  trans-113.6139.1-174.2-58.9-59.4-45.900110.7Q374 K403 S407 K517Q374-Q519 VanDerWaalsContact NE2-OE1 3.09Å; K403-Q519 HydrophobicContact CB-CB 4.47Å; K403-Q519 HydrophobicContact CD-CB 4.1Å; S407-Q519 WeakPolarHBondContact CB-O 3.33Å; S407-Q519 PolarHBondContact OG-N 2.57Å; S407-Q519 VanDerWaalsContact OG-N 3.12Å; S407-Q519 PolarHBondContact OG-O 3.36Å; K517-Q519 PolarHBondContact O-NE2 2.98Å; K517-Q519 VanDerWaalsContact O-NE2 3.08Å
520W98Very high96.4Very high9 Ų961 Ų613%0.03431%0.308CS..  trans-135.6142.2-172-57.4103.1000111.1Y342 Q374 E377 L380 F399 N404 S407 L408 I411 L518 I522Y342-W520 HydrophobicContact CD2-CZ2 4.39Å; Y342-W520 AromaticContact CD2-NE1 3.92Å; Q374-W520 PolarHBondContact OE1-O 2.87Å; E377-W520 VanDerWaalsContact CD-CD1 3.47Å; E377-W520 VanDerWaalsContact CG-CD1 3.48Å; E377-W520 HydrophobicContact CG-CG 4.39Å; E377-W520 PolarHBondContact OE1-NE1 3.32Å; L380-W520 HydrophobicContact CD2-CD2 3.89Å; L380-W520 HydrophobicContact CD2-CE3 3.91Å; L380-W520 HydrophobicContact CD2-CH2 3.54Å; L380-W520 HydrophobicContact CD2-CZ2 3.5Å; L380-W520 VanDerWaalsContact CD2-CZ2 3.5Å; L380-W520 HydrophobicContact CD2-CZ3 3.76Å; F399-W520 HydrophobicContact CD1-CE3 4.37Å; F399-W520 AromaticContact CD1-CZ3 3.83Å; F399-W520 HydrophobicContact CD1-CZ3 3.83Å; F399-W520 AromaticContact CE1-CE3 3.91Å; F399-W520 HydrophobicContact CE1-CE3 3.91Å; F399-W520 AromaticContact CE1-CZ3 3.64Å; F399-W520 HydrophobicContact CE1-CZ3 3.64Å; N404-W520 HydrophobicContact CB-CE3 4.42Å; N404-W520 WeakPolarHBondContact OD1-CA 3.24Å; S407-W520 VanDerWaalsContact CB-CH2 3.4Å; L408-W520 HydrophobicContact CB-CZ3 4.45Å; I411-W520 HydrophobicContact CD1-CH2 3.92Å; I411-W520 HydrophobicContact CD1-CZ2 3.93Å; L518-W520 HydrophobicContact CB-CZ2 4.33Å; L518-W520 HydrophobicContact CD1-CZ2 4.17Å; W520-I522 HydrophobicContact CB-CD1 3.94Å; W520-I522 HydrophobicContact CB-CG1 4.01Å; W520-I522 HydrophobicContact CG-CD1 4.3Å
521E96.9Very high96.7Very high106 Ų10658.9 Ų58.950%0.49530%0.298SS..  trans-126.475.9171.9-74.8173174.700106.3K403 N404 P523K403-E521 HydrophobicContact CD-CG 4.07Å; K403-E521 WeakPolarHBondContact CD-OE1 3.28Å; K403-E521 WeakPolarHBondContact CE-OE1 3.41Å; K403-E521 IonicContact NZ-OE1 3.96Å; K403-E521 PolarHBondContact NZ-OE1 2.93Å; N404-E521 PolarHBondContact ND2-O 3.47Å; N404-E521 PolarHBondContact OD1-N 2.98Å; E521-P523 VanDerWaalsContact O-CD 3.3Å; E521-P523 WeakPolarHBondContact O-CD 3.34Å
522I97.8Very high97.2Very high11 Ų1161.7 Ų61.76%0.05630%0.299CS..  trans-94.9105.2-174.8-59.7165.3000108.1L380 W520 C526 Q527 I530L380-I522 HydrophobicContact CD1-CD1 4.1Å; L380-I522 HydrophobicContact CD2-CD1 4.36Å; W520-I522 HydrophobicContact CB-CD1 3.94Å; W520-I522 HydrophobicContact CB-CG1 4.01Å; W520-I522 HydrophobicContact CG-CD1 4.3Å; I522-C526 HydrophobicContact CG2-CB 3.74Å; I522-Q527 HydrophobicContact CG2-CG 3.71Å; I522-Q527 PolarHBondContact O-NE2 3.03Å; I522-I530 HydrophobicContact CG2-CD1 3.9Å
523P97.7Very high97.5Very high48 Ų4861.7 Ų61.731%0.31230%0.3SS..  trans-69.3159.8-179.633.2-37.8000110.9Y398 E521 E525 C526 Q527Y398-P523 HydrophobicContact CD1-CG 3.63Å; Y398-P523 HydrophobicContact CE1-CG 3.83Å; E521-P523 VanDerWaalsContact O-CD 3.3Å; E521-P523 WeakPolarHBondContact O-CD 3.34Å; P523-E525 VanDerWaalsContact C-N 3.25Å; P523-E525 WeakPolarHBondContact CB-OE2 3.21Å; P523-E525 PolarHBondContact O-N 3.3Å; P523-C526 HydrophobicContact CG-CB 3.95Å; P523-C526 WeakPolarHBondContact O-CA 3.38Å; P523-C526 WeakPolarHBondContact O-CB 3.27Å; P523-C526 PolarHBondContact O-N 3.21Å; P523-Q527 WeakPolarHBondContact O-CG 3.28Å; P523-Q527 PolarHBondContact O-N 3.08Å; P523-Q527 VanDerWaalsContact O-N 3.12Å
524E98.1Very high98Very high150 Ų15060 Ų6070%0.70129%0.288SS*.Hα-helixtrans-55.1-39.3-175.4-68.6-178.717800112.3C526 Q527 E528E524-C526 PolarHBondContact O-N 3.29Å; E524-Q527 WeakPolarHBondContact O-CA 3.14Å; E524-Q527 WeakPolarHBondContact O-CB 3.48Å; E524-Q527 PolarHBondContact O-N 3.13Å; E524-E528 PolarHBondContact O-N 3.27Å
525E98.2Very high98.2Very high111 Ų11159.9 Ų59.952%0.51929%0.294SS..Hα-helixtrans-63.4-31.1178-55.287.116500112.3Y398 P523 V529Y398-E525 WeakPolarHBondContact OH-CB 3.35Å; P523-E525 VanDerWaalsContact C-N 3.25Å; P523-E525 WeakPolarHBondContact CB-OE2 3.21Å; P523-E525 PolarHBondContact O-N 3.3Å; E525-V529 WeakPolarHBondContact O-CG2 3.31Å
526C98.4Very high98.2Very high0 Ų061.1 Ų61.10%030%0.302CS..Hα-helixtrans-75.4-35.2173.2-172.40000111.2Y398 I522 P523 E524 E528 V529 I530Y398-C526 HydrophobicContact CD1-CB 3.98Å; Y398-C526 HydrophobicContact CD2-CB 3.54Å; Y398-C526 WeakPolarHBondContact CD2-SG 3.27Å; Y398-C526 HydrophobicContact CE1-CB 4.18Å; Y398-C526 HydrophobicContact CE2-CB 3.75Å; Y398-C526 HydrophobicContact CG-CB 3.66Å; I522-C526 HydrophobicContact CG2-CB 3.74Å; P523-C526 HydrophobicContact CG-CB 3.95Å; P523-C526 WeakPolarHBondContact O-CA 3.38Å; P523-C526 WeakPolarHBondContact O-CB 3.27Å; P523-C526 PolarHBondContact O-N 3.21Å; E524-C526 PolarHBondContact O-N 3.29Å; C526-E528 VanDerWaalsContact C-N 3.31Å; C526-E528 PolarHBondContact O-N 3.06Å; C526-V529 PolarHBondContact O-N 3.33Å; C526-V529 VanDerWaalsContact O-N 3.17Å; C526-I530 WeakPolarHBondContact O-CG1 3.46Å; C526-I530 PolarHBondContact O-N 3.11Å
527Q98.5Very high98.3Very high55 Ų5558.1 Ų58.126%0.25728%0.283SS..Hα-helixtrans-63-38.4175.8-58.7-179.941.900111.2I522 P523 E524 V529 I530 E531I522-Q527 HydrophobicContact CG2-CG 3.71Å; I522-Q527 PolarHBondContact O-NE2 3.03Å; P523-Q527 WeakPolarHBondContact O-CG 3.28Å; P523-Q527 PolarHBondContact O-N 3.08Å; P523-Q527 VanDerWaalsContact O-N 3.12Å; E524-Q527 WeakPolarHBondContact O-CA 3.14Å; E524-Q527 WeakPolarHBondContact O-CB 3.48Å; E524-Q527 PolarHBondContact O-N 3.13Å; Q527-V529 VanDerWaalsContact C-N 3.33Å; Q527-V529 PolarHBondContact O-N 3.37Å; Q527-I530 WeakPolarHBondContact O-CB 3.31Å; Q527-I530 PolarHBondContact O-N 3.16Å; Q527-E531 WeakPolarHBondContact O-CG 3.39Å; Q527-E531 PolarHBondContact O-N 2.86Å
528E98.4Very high98.3Very high140 Ų14058.7 Ų58.765%0.65429%0.29SS*.Hα-helixtrans-60-41172.5-67.7-178.9175.400112.6E524 C526 I530 E531 R532E524-E528 PolarHBondContact O-N 3.27Å; C526-E528 VanDerWaalsContact C-N 3.31Å; C526-E528 PolarHBondContact O-N 3.06Å; E528-I530 VanDerWaalsContact C-N 3.33Å; E528-E531 PolarHBondContact O-N 2.95Å; E528-R532 WeakPolarHBondContact O-CB 3.49Å; E528-R532 PolarHBondContact O-N 3.06Å
529V98.5Very high98.3Very high40 Ų4061.1 Ų61.124%0.24231%0.311CS..Hα-helixtrans-67.3-35.9176.1-177.10000111.6L383 P390 A394 E525 C526 Q527 S533L383-V529 HydrophobicContact CD2-CB 4.5Å; L383-V529 HydrophobicContact CD2-CG1 3.84Å; P390-V529 HydrophobicContact CB-CG1 4.48Å; A394-V529 HydrophobicContact CB-CG1 4.09Å; E525-V529 WeakPolarHBondContact O-CG2 3.31Å; C526-V529 PolarHBondContact O-N 3.33Å; C526-V529 VanDerWaalsContact O-N 3.17Å; Q527-V529 VanDerWaalsContact C-N 3.33Å; Q527-V529 PolarHBondContact O-N 3.37Å; V529-S533 WeakPolarHBondContact O-CB 3.38Å; V529-S533 PolarHBondContact O-N 2.83Å; V529-S533 PolarHBondContact O-OG 3.45Å
530I98.8Very high98.3Very high2 Ų258.9 Ų58.91%0.0130%0.302CS..Hα-helixtrans-61.4-50.8173.2-71.4164000110.1K379 L380 A382 L383 I522 C526 Q527 E528 R532 S533 L534K379-I530 HydrophobicContact CB-CG2 3.6Å; K379-I530 VanDerWaalsContact O-CG2 3.24Å; K379-I530 WeakPolarHBondContact O-CG2 3.43Å; L380-I530 HydrophobicContact CD1-CD1 4Å; A382-I530 HydrophobicContact CB-CG2 4.39Å; L383-I530 HydrophobicContact CD1-CD1 4.42Å; L383-I530 HydrophobicContact CD1-CG1 3.79Å; L383-I530 HydrophobicContact CD2-CG1 3.93Å; L383-I530 HydrophobicContact CG-CG1 3.74Å; I522-I530 HydrophobicContact CG2-CD1 3.9Å; C526-I530 WeakPolarHBondContact O-CG1 3.46Å; C526-I530 PolarHBondContact O-N 3.11Å; Q527-I530 WeakPolarHBondContact O-CB 3.31Å; Q527-I530 PolarHBondContact O-N 3.16Å; E528-I530 VanDerWaalsContact C-N 3.33Å; I530-R532 PolarHBondContact O-N 2.75Å; I530-S533 PolarHBondContact O-N 3.23Å; I530-L534 WeakPolarHBondContact O-CB 3.41Å; I530-L534 PolarHBondContact O-N 3.04Å
531E98.6Very high98.3Very high85 Ų8558.6 Ų58.640%0.39730%0.302SS..Hα-helixtrans-64.3-38.8-180-66.9-63164.900112.3K379 Q527 E528 L534 S535K379-E531 WeakPolarHBondContact CD-OE1 3.48Å; K379-E531 WeakPolarHBondContact CE-OE1 3.4Å; K379-E531 IonicContact NZ-OE1 2.84Å; K379-E531 PolarHBondContact NZ-OE1 3.12Å; K379-E531 IonicContact NZ-OE2 3.23Å; K379-E531 PolarHBondContact NZ-OE2 2.83Å; Q527-E531 WeakPolarHBondContact O-CG 3.39Å; Q527-E531 PolarHBondContact O-N 2.86Å; E528-E531 PolarHBondContact O-N 2.95Å; E531-L534 WeakPolarHBondContact O-CB 3.45Å; E531-L534 PolarHBondContact O-N 3.43Å; E531-S535 PolarHBondContact O-N 3.13Å
532R98.5Very high98.4Very high192 Ų19259 Ų5973%0.72531%0.307SS*.Hα-helixtrans-64.2-45174.8-174.2175.8-179.5166.82111.8E528 I530 L534 S535 T536E528-R532 WeakPolarHBondContact O-CB 3.49Å; E528-R532 PolarHBondContact O-N 3.06Å; I530-R532 PolarHBondContact O-N 2.75Å; R532-L534 VanDerWaalsContact C-N 3.28Å; R532-L534 PolarHBondContact O-N 3.03Å; R532-S535 PolarHBondContact O-N 3.41Å; R532-T536 PolarHBondContact O-N 2.69Å; R532-T536 VanDerWaalsContact O-N 3.08Å; R532-T536 PolarHBondContact O-OG1 3.5Å
533S98.6Very high98.4Very high5 Ų560.2 Ų60.24%0.03531%0.314CS..Hα-helixtrans-61.7-39.2175.5-61.20000111.5A382 V529 I530 T536 A537A382-S533 WeakPolarHBondContact O-CB 3.22Å; V529-S533 WeakPolarHBondContact O-CB 3.38Å; V529-S533 PolarHBondContact O-N 2.83Å; V529-S533 PolarHBondContact O-OG 3.45Å; I530-S533 PolarHBondContact O-N 3.23Å; S533-T536 PolarHBondContact O-N 3.22Å; S533-A537 WeakPolarHBondContact O-CB 3.25Å; S533-A537 PolarHBondContact O-N 3.18Å
534L98.6Very high98.4Very high17 Ų1758 Ų589%0.08930%0.299CS..Hα-helixtrans-62.7-47.1174.8179.956.8000111.2K379 A382 C448 Y449 I530 E531 R532 T536 A537 T538K379-L534 HydrophobicContact CD-CD2 3.65Å; K379-L534 HydrophobicContact CG-CD2 4.06Å; A382-L534 HydrophobicContact CB-CB 3.75Å; A382-L534 HydrophobicContact CB-CD1 4.23Å; C448-L534 HydrophobicContact CB-CD1 3.81Å; Y449-L534 HydrophobicContact CD1-CD1 3.83Å; Y449-L534 HydrophobicContact CD1-CD2 4.22Å; I530-L534 WeakPolarHBondContact O-CB 3.41Å; I530-L534 PolarHBondContact O-N 3.04Å; E531-L534 WeakPolarHBondContact O-CB 3.45Å; E531-L534 PolarHBondContact O-N 3.43Å; R532-L534 VanDerWaalsContact C-N 3.28Å; R532-L534 PolarHBondContact O-N 3.03Å; L534-T536 VanDerWaalsContact C-N 3.34Å; L534-T536 PolarHBondContact O-N 3.44Å; L534-A537 PolarHBondContact O-N 3.41Å; L534-A537 VanDerWaalsContact O-N 3.15Å; L534-T538 WeakPolarHBondContact O-CB 3.3Å; L534-T538 PolarHBondContact O-N 2.84Å; L534-T538 PolarHBondContact O-OG1 3.5Å; L534-T538 VanDerWaalsContact O-OG1 3.08Å
535S98.6Very high98.4Very high81 Ų8152 Ų5257%0.56627%0.272SS*.Hα-helixtrans-57.9-45.1177.6179.10000112.2E531 R532 A539E531-S535 PolarHBondContact O-N 3.13Å; R532-S535 PolarHBondContact O-N 3.41Å; S535-A539 WeakPolarHBondContact O-CB 3.17Å; S535-A539 PolarHBondContact O-N 3.16Å
536T98.4Very high98.3Very high47 Ų4746.8 Ų46.829%0.28825%0.248SC..Hα-helixtrans-60.7-46.3174.2-620000111.8P247 R532 S533 L534 L540P247-T536 HydrophobicContact CG-CG2 4.19Å; R532-T536 PolarHBondContact O-N 2.69Å; R532-T536 VanDerWaalsContact O-N 3.08Å; R532-T536 PolarHBondContact O-OG1 3.5Å; S533-T536 PolarHBondContact O-N 3.22Å; L534-T536 VanDerWaalsContact C-N 3.34Å; L534-T536 PolarHBondContact O-N 3.44Å; T536-L540 PolarHBondContact O-N 2.89Å; T536-L540 VanDerWaalsContact O-N 3.1Å
537A98.5Very high98.2Very high0 Ų046.9 Ų46.90%025%0.248CC..Hα-helixtrans-67.8-41.2-178.100000112.3M249 A385 C448 S533 L534 L540 A541M249-A537 HydrophobicContact CE-CB 4.16Å; M249-A537 WeakPolarHBondContact CE-O 3.4Å; A385-A537 HydrophobicContact CB-CB 3.71Å; C448-A537 HydrophobicContact CB-CB 3.73Å; S533-A537 WeakPolarHBondContact O-CB 3.25Å; S533-A537 PolarHBondContact O-N 3.18Å; L534-A537 PolarHBondContact O-N 3.41Å; L534-A537 VanDerWaalsContact O-N 3.15Å; A537-L540 WeakPolarHBondContact O-CB 3.32Å; A537-L540 PolarHBondContact O-N 3.47Å; A537-A541 WeakPolarHBondContact O-CB 3.28Å; A537-A541 PolarHBondContact O-N 2.96Å
538T98.6Very high98.1Very high50 Ų5044.3 Ų44.331%0.30724%0.236SC..Hα-helixtrans-63.5-46.4175.9-64.60000111.1L534 L540 A541 D542L534-T538 WeakPolarHBondContact O-CB 3.3Å; L534-T538 PolarHBondContact O-N 2.84Å; L534-T538 PolarHBondContact O-OG1 3.5Å; L534-T538 VanDerWaalsContact O-OG1 3.08Å; T538-L540 PolarHBondContact O-N 3.22Å; T538-A541 PolarHBondContact O-N 3.36Å; T538-A541 VanDerWaalsContact O-N 3.1Å; T538-D542 WeakPolarHBondContact CG2-OD2 3.47Å; T538-D542 WeakPolarHBondContact O-CB 3.49Å; T538-D542 VanDerWaalsContact O-CG 3.26Å; T538-D542 PolarHBondContact O-N 3.04Å
539A98.5Very high98Very high63 Ų6338.1 Ų38.152%0.52121%0.207SC..Hα-helixtrans-57.9-39.4175.100000111.9S535 D543S535-A539 WeakPolarHBondContact O-CB 3.17Å; S535-A539 PolarHBondContact O-N 3.16Å; A539-D543 WeakPolarHBondContact O-CB 3.41Å; A539-D543 PolarHBondContact O-N 3.36Å
540L98.2Very high97.9Very high24 Ų2437.8 Ų37.813%0.12620%0.203CC..Hα-helixtrans-67.1-42.8175.1179.164.6000112.5P247 V250 T536 A537 T538 V544P247-L540 HydrophobicContact CB-CD2 3.57Å; P247-L540 HydrophobicContact CG-CD2 4.01Å; V250-L540 HydrophobicContact CB-CD2 3.98Å; V250-L540 HydrophobicContact CB-CG 4.16Å; V250-L540 HydrophobicContact CG2-CD2 4.25Å; V250-L540 HydrophobicContact CG2-CG 4.17Å; T536-L540 PolarHBondContact O-N 2.89Å; T536-L540 VanDerWaalsContact O-N 3.1Å; A537-L540 WeakPolarHBondContact O-CB 3.32Å; A537-L540 PolarHBondContact O-N 3.47Å; T538-L540 PolarHBondContact O-N 3.22Å; L540-V544 WeakPolarHBondContact O-CG2 3.26Å
541A98.3Very high97.7Very high4 Ų437.9 Ų37.93%0.03320%0.204CC..Hα-helixtrans-68.7-43.6-178.900000112.5M249 H445 A537 T538 D543 V544M249-A541 HydrophobicContact CE-CB 4.02Å; H445-A541 HydrophobicContact CB-CB 4.07Å; A537-A541 WeakPolarHBondContact O-CB 3.28Å; A537-A541 PolarHBondContact O-N 2.96Å; T538-A541 PolarHBondContact O-N 3.36Å; T538-A541 VanDerWaalsContact O-N 3.1Å; A541-D543 PolarHBondContact O-N 3.49Å; A541-V544 PolarHBondContact O-N 2.95Å
542D98.1Very high97.5Very high115 Ų11539.2 Ų39.262%0.61521%0.214SC*.Hα-helixtrans-64-28.6179-69.8-16.1000111.7T538 V544 I737T538-D542 WeakPolarHBondContact CG2-OD2 3.47Å; T538-D542 WeakPolarHBondContact O-CB 3.49Å; T538-D542 VanDerWaalsContact O-CG 3.26Å; T538-D542 PolarHBondContact O-N 3.04Å; D542-V544 VanDerWaalsContact C-N 3.33Å; D542-I737 WeakPolarHBondContact O-CD1 3.38Å
543D98.2Very high97.4Very high36 Ų3634.5 Ų34.519%0.19321%0.206CC..THydrogen-bonded Turntrans-80-8.6176.7-177.448.2000113.5A539 A541 K736 I737 S738A539-D543 WeakPolarHBondContact O-CB 3.41Å; A539-D543 PolarHBondContact O-N 3.36Å; A541-D543 PolarHBondContact O-N 3.49Å; D543-K736 CarbonylContact O-C 3.43Å; D543-K736 VanDerWaalsContact O-CA 3.3Å; D543-K736 WeakPolarHBondContact O-CA 3.43Å; D543-K736 WeakPolarHBondContact OD2-CD 3.38Å; D543-K736 IonicContact OD2-NZ 3.2Å; D543-K736 PolarHBondContact OD2-NZ 3.24Å; D543-I737 PolarHBondContact O-N 2.91Å; D543-I737 PolarHBondContact OD1-N 3.41Å; D543-S738 WeakPolarHBondContact OD1-CB 3.33Å; D543-S738 PolarHBondContact OD1-N 3.14Å; D543-S738 PolarHBondContact OD1-OG 2.93Å
544V97.5Very high97.3Very high0 Ų034.7 Ų34.70%021%0.207CC..EExtended strand (participates in β ladder)trans-90.5123179.6-177.80000111.2V250 K441 L540 A541 D542 F546 K736V250-V544 HydrophobicContact CB-CG2 4.4Å; V250-V544 HydrophobicContact CG1-CG2 3.52Å; V250-V544 HydrophobicContact CG2-CG2 4.05Å; K441-V544 WeakPolarHBondContact CE-O 3.38Å; K441-V544 PolarHBondContact NZ-O 2.95Å; L540-V544 WeakPolarHBondContact O-CG2 3.26Å; A541-V544 PolarHBondContact O-N 2.95Å; D542-V544 VanDerWaalsContact C-N 3.33Å; V544-F546 HydrophobicContact CB-CE2 4.4Å; V544-F546 HydrophobicContact CG1-CD2 3.52Å; V544-F546 HydrophobicContact CG1-CE2 3.24Å; V544-F546 HydrophobicContact CG1-CZ 4.11Å; V544-K736 HydrophobicContact CG2-CD 4.2Å
545D97.4Very high97.1Very high25 Ų2533.9 Ų33.913%0.13420%0.202CC..EExtended strand (participates in β ladder)trans-92145167.3-172.232.6000110.8S734 S735 I737 S744D545-S734 VanDerWaalsContact O-CA 3.23Å; D545-S734 WeakPolarHBondContact O-CA 3.34Å; D545-S735 PolarHBondContact N-O 2.92Å; D545-S735 PolarHBondContact O-N 3.44Å; D545-S735 VanDerWaalsContact O-N 3.11Å; D545-I737 HydrophobicContact CB-CG1 3.84Å; D545-S744 WeakPolarHBondContact CB-OG 3.27Å; D545-S744 PolarHBondContact O-OG 2.83Å; D545-S744 WeakPolarHBondContact OD2-CB 3.13Å; D545-S744 PolarHBondContact OD2-N 3.31Å; D545-S744 PolarHBondContact OD2-OG 3.41Å
546F96.6Very high96.9Very high2 Ų232.3 Ų32.31%0.00919%0.185CC..EExtended strand (participates in β ladder)trans-138.7140.2178.7-91.7-77.9000109.9F255 A440 K441 I444 V544 V733 S734 H745F255-F546 AromaticContact CE1-CE1 3.8Å; F255-F546 HydrophobicContact CE1-CE1 3.8Å; F255-F546 HydrophobicContact CE1-CZ 4.1Å; F255-F546 HydrophobicContact CZ-CE1 4.29Å; A440-F546 HydrophobicContact CB-CD1 4.21Å; A440-F546 HydrophobicContact CB-CG 4.35Å; K441-F546 HydrophobicContact CG-CB 4.21Å; K441-F546 HydrophobicContact CG-CD2 3.71Å; K441-F546 HydrophobicContact CG-CG 4.32Å; I444-F546 HydrophobicContact CD1-CE2 4.15Å; I444-F546 HydrophobicContact CD1-CZ 3.62Å; I444-F546 HydrophobicContact CG2-CE2 3.72Å; I444-F546 HydrophobicContact CG2-CZ 4.07Å; V544-F546 HydrophobicContact CB-CE2 4.4Å; V544-F546 HydrophobicContact CG1-CD2 3.52Å; V544-F546 HydrophobicContact CG1-CE2 3.24Å; V544-F546 HydrophobicContact CG1-CZ 4.11Å; F546-V733 CarbonylContact C-O 3.37Å; F546-V733 WeakPolarHBondContact CA-O 3.48Å; F546-S734 VanDerWaalsContact CE1-CB 3.48Å; F546-H745 PolarHBondContact O-CE1 2.87Å
547H97.8Very high96.6Very high2 Ų230.6 Ų30.61%0.00918%0.177CC..EExtended strand (participates in β ladder)trans-139.1111.3169.9-174.258.2000110.3E433 D437 F549 V733 S744 H745E433-H547 IonicContact OE2-CE1 2.73Å; D437-H547 WeakPolarHBondContact OD1-CA 3.3Å; D437-H547 IonicContact OD2-ND1 3.71Å; H547-F549 AromaticContact CD2-CD1 3.34Å; H547-F549 WeakPolarHBondContact CD2-CD1 3.43Å; H547-F549 AromaticContact CD2-CE1 3.7Å; H547-F549 AromaticContact NE2-CD1 3.36Å; H547-F549 WeakPolarHBondContact NE2-CD1 3.32Å; H547-F549 AromaticContact NE2-CE1 3.97Å; H547-F549 AromaticContact NE2-CG 3.95Å; H547-V733 HydrophobicContact CB-CB 4.43Å; H547-V733 PolarHBondContact N-O 3.08Å; H547-V733 PolarHBondContact O-N 3.29Å; H547-S744 WeakPolarHBondContact CB-O 3.46Å; H547-H745 AromaticContact CE1-CD2 3.66Å; H547-H745 AromaticContact CG-CD2 3.9Å; H547-H745 AromaticContact CG-CG 3.92Å; H547-H745 AromaticContact ND1-CD2 3.2Å; H547-H745 PolarHBondContact ND1-CD2 3.36Å; H547-H745 AromaticContact ND1-CE1 3.78Å; H547-H745 AromaticContact ND1-CG 3.69Å; H547-H745 AromaticContact ND1-NE2 3.29Å; H547-H745 PolarHBondContact ND1-NE2 3.37Å
548S96.4Very high96.5Very high0 Ų033.9 Ų33.90%019%0.194CC..EExtended strand (participates in β ladder)trans-117123.9-178.9-173.40000110.4L436 D437 H730 F731 H732L436-S548 WeakPolarHBondContact CD1-O 3.49Å; D437-S548 PolarHBondContact OD1-N 2.74Å; S548-H730 PolarHBondContact OG-NE2 2.8Å; S548-F731 WeakPolarHBondContact CA-O 3.47Å; S548-F731 PolarHBondContact OG-O 2.9Å; S548-H732 PolarHBondContact OG-CE1 3.5Å; S548-H732 PolarHBondContact OG-ND1 3.14Å
549F95.9Very high96.4Very high10 Ų1031.5 Ų31.54%0.04418%0.179CC..EExtended strand (participates in β ladder)trans-148.2149.9-173.865.4-86.4000113.1H547 F551 H730 F731 V733 I751 Q752H547-F549 AromaticContact CD2-CD1 3.34Å; H547-F549 WeakPolarHBondContact CD2-CD1 3.43Å; H547-F549 AromaticContact CD2-CE1 3.7Å; H547-F549 AromaticContact NE2-CD1 3.36Å; H547-F549 WeakPolarHBondContact NE2-CD1 3.32Å; H547-F549 AromaticContact NE2-CE1 3.97Å; H547-F549 AromaticContact NE2-CG 3.95Å; F549-F551 HydrophobicContact CE2-CB 4.48Å; F549-H730 PolarHBondContact O-CD2 3.15Å; F549-H730 VanDerWaalsContact O-CD2 3.26Å; F549-F731 HydrophobicContact CD1-CB 4.24Å; F549-F731 HydrophobicContact CE1-CB 3.72Å; F549-F731 HydrophobicContact CE1-CG 4.49Å; F549-F731 HydrophobicContact CE2-CB 4.07Å; F549-F731 AromaticContact CE2-CD2 3.78Å; F549-F731 HydrophobicContact CE2-CD2 3.78Å; F549-F731 HydrophobicContact CE2-CG 4.2Å; F549-F731 HydrophobicContact CZ-CB 3.63Å; F549-F731 AromaticContact CZ-CD2 3.96Å; F549-F731 HydrophobicContact CZ-CD2 3.96Å; F549-F731 AromaticContact CZ-CG 3.92Å; F549-F731 HydrophobicContact CZ-CG 3.92Å; F549-F731 PolarHBondContact N-O 3.46Å; F549-F731 PolarHBondContact O-N 3.05Å; F549-V733 HydrophobicContact CE1-CG2 4.19Å; F549-I751 HydrophobicContact CZ-CB 4.39Å; F549-I751 HydrophobicContact CZ-CG2 4.34Å; F549-Q752 HydrophobicContact CD2-CG 4.05Å; F549-Q752 HydrophobicContact CE2-CG 3.42Å; F549-Q752 VanDerWaalsContact CE2-CG 3.42Å; F549-Q752 HydrophobicContact CZ-CG 4.01Å
550L94.8Very high96.2Very high33 Ų3334.1 Ų34.117%0.17318%0.179CC..EExtended strand (participates in β ladder)trans-87.3124.3170.6-175.967.9000109.3L260 Y261 D552 L724 H730L260-L550 HydrophobicContact CD2-CD2 3.95Å; Y261-L550 VanDerWaalsContact OH-CD2 3.3Å; Y261-L550 WeakPolarHBondContact OH-CD2 3.39Å; L550-D552 HydrophobicContact CD2-CB 4.27Å; L550-D552 HydrophobicContact CG-CB 4.32Å; L550-L724 HydrophobicContact CD1-CD1 3.65Å; L550-H730 HydrophobicContact CD1-CB 4.43Å
551F96.1Very high96Very high4 Ų441.1 Ų41.12%0.01821%0.209CC..EExtended strand (participates in β ladder)trans-95106.6165.3-179.2-96.6000108.6F549 T553 F554 S728 I729 F731 Q752 M755F549-F551 HydrophobicContact CE2-CB 4.48Å; F551-T553 HydrophobicContact CZ-CG2 4.43Å; F551-F554 VanDerWaalsContact CD1-O 3.3Å; F551-F554 WeakPolarHBondContact CD1-O 3.46Å; F551-F554 AromaticContact CE1-CD1 3.84Å; F551-F554 HydrophobicContact CE1-CD1 3.84Å; F551-F554 AromaticContact CE1-CD2 3.92Å; F551-F554 HydrophobicContact CE1-CD2 3.92Å; F551-F554 AromaticContact CE1-CE1 3.75Å; F551-F554 HydrophobicContact CE1-CE1 3.75Å; F551-F554 AromaticContact CE1-CE2 3.82Å; F551-F554 HydrophobicContact CE1-CE2 3.82Å; F551-F554 AromaticContact CE1-CG 3.92Å; F551-F554 HydrophobicContact CE1-CG 3.92Å; F551-F554 AromaticContact CE1-CZ 3.73Å; F551-F554 HydrophobicContact CE1-CZ 3.73Å; F551-F554 VanDerWaalsContact CE1-O 3.24Å; F551-F554 WeakPolarHBondContact CE1-O 3.49Å; F551-F554 AromaticContact CZ-CD1 3.87Å; F551-F554 HydrophobicContact CZ-CD1 3.87Å; F551-F554 AromaticContact CZ-CE1 3.49Å; F551-F554 HydrophobicContact CZ-CE1 3.49Å; F551-F554 VanDerWaalsContact CZ-CE1 3.49Å; F551-F554 HydrophobicContact CZ-CE2 4.29Å; F551-F554 HydrophobicContact CZ-CG 4.42Å; F551-F554 AromaticContact CZ-CZ 3.72Å; F551-F554 HydrophobicContact CZ-CZ 3.72Å; F551-S728 CarbonylContact O-C 3.54Å; F551-S728 VanDerWaalsContact O-CA 3.24Å; F551-S728 WeakPolarHBondContact O-CA 3.47Å; F551-I729 WeakPolarHBondContact CA-O 3.2Å; F551-I729 WeakPolarHBondContact CB-O 3.25Å; F551-I729 PolarHBondContact N-O 2.83Å; F551-I729 PolarHBondContact O-N 3.32Å; F551-F731 HydrophobicContact CB-CD2 4.21Å; F551-F731 HydrophobicContact CB-CE2 4.04Å; F551-Q752 HydrophobicContact CD2-CB 4.44Å; F551-Q752 HydrophobicContact CD2-CG 4.2Å; F551-M755 HydrophobicContact CD1-CE 4.41Å; F551-M755 HydrophobicContact CE1-CB 4.34Å; F551-M755 HydrophobicContact CE1-CE 4.15Å; F551-M755 HydrophobicContact CE2-CB 3.98Å; F551-M755 HydrophobicContact CZ-CB 3.74Å
552D94.3Very high95.7Very high114 Ų11441.6 Ų41.661%0.6121%0.211SC*.  trans-110.95.2-174.165.5-9.4000113.6L550 N727L550-D552 HydrophobicContact CD2-CB 4.27Å; L550-D552 HydrophobicContact CG-CB 4.32Å; D552-N727 CarbonylContact C-O 3.56Å
553T96.6Very high95.4Very high92 Ų9245.8 Ų45.856%0.56422%0.224SC*.SBendtrans-68.2-38.1179.1-49.70000111.6F551F551-T553 HydrophobicContact CZ-CG2 4.43Å
554F96Very high95.2Very high9 Ų944.6 Ų44.64%0.03922%0.218CC..  trans-165.5163.2170.459.4-97.7000111.1F551 L558 I559 F569 N727 M755 M759F551-F554 VanDerWaalsContact CD1-O 3.3Å; F551-F554 WeakPolarHBondContact CD1-O 3.46Å; F551-F554 AromaticContact CE1-CD1 3.84Å; F551-F554 HydrophobicContact CE1-CD1 3.84Å; F551-F554 AromaticContact CE1-CD2 3.92Å; F551-F554 HydrophobicContact CE1-CD2 3.92Å; F551-F554 AromaticContact CE1-CE1 3.75Å; F551-F554 HydrophobicContact CE1-CE1 3.75Å; F551-F554 AromaticContact CE1-CE2 3.82Å; F551-F554 HydrophobicContact CE1-CE2 3.82Å; F551-F554 AromaticContact CE1-CG 3.92Å; F551-F554 HydrophobicContact CE1-CG 3.92Å; F551-F554 AromaticContact CE1-CZ 3.73Å; F551-F554 HydrophobicContact CE1-CZ 3.73Å; F551-F554 VanDerWaalsContact CE1-O 3.24Å; F551-F554 WeakPolarHBondContact CE1-O 3.49Å; F551-F554 AromaticContact CZ-CD1 3.87Å; F551-F554 HydrophobicContact CZ-CD1 3.87Å; F551-F554 AromaticContact CZ-CE1 3.49Å; F551-F554 HydrophobicContact CZ-CE1 3.49Å; F551-F554 VanDerWaalsContact CZ-CE1 3.49Å; F551-F554 HydrophobicContact CZ-CE2 4.29Å; F551-F554 HydrophobicContact CZ-CG 4.42Å; F551-F554 AromaticContact CZ-CZ 3.72Å; F551-F554 HydrophobicContact CZ-CZ 3.72Å; F554-L558 HydrophobicContact CB-CB 3.93Å; F554-L558 HydrophobicContact CB-CD2 3.74Å; F554-L558 HydrophobicContact CB-CG 4.48Å; F554-L558 HydrophobicContact CD1-CD2 4.23Å; F554-L558 HydrophobicContact CG-CB 4.44Å; F554-L558 HydrophobicContact CG-CD2 3.97Å; F554-I559 HydrophobicContact CD2-CD1 4.27Å; F554-I559 HydrophobicContact CD2-CG1 3.98Å; F554-I559 HydrophobicContact CE2-CD1 4.06Å; F554-I559 HydrophobicContact CE2-CG1 3.86Å; F554-F569 AromaticContact CE2-CE1 3.99Å; F554-F569 HydrophobicContact CE2-CE1 3.99Å; F554-F569 HydrophobicContact CE2-CZ 4.28Å; F554-F569 HydrophobicContact CZ-CE1 4.07Å; F554-F569 HydrophobicContact CZ-CZ 4.2Å; F554-N727 CarbonylContact C-O 3.28Å; F554-N727 VanDerWaalsContact CA-O 3.26Å; F554-N727 WeakPolarHBondContact CA-O 3.29Å; F554-N727 PolarHBondContact N-O 3.17Å; F554-M755 HydrophobicContact CE2-CE 3.82Å; F554-M755 HydrophobicContact CZ-CB 4.05Å; F554-M755 HydrophobicContact CZ-CE 4.16Å; F554-M755 WeakPolarHBondContact CZ-O 3.29Å; F554-M759 HydrophobicContact CD1-CB 4.48Å; F554-M759 HydrophobicContact CD1-CE 4.43Å; F554-M759 HydrophobicContact CD1-CG 4.21Å; F554-M759 HydrophobicContact CD2-CE 3.71Å; F554-M759 HydrophobicContact CE1-CB 3.69Å; F554-M759 HydrophobicContact CE1-CE 4.24Å; F554-M759 HydrophobicContact CE1-CG 3.91Å; F554-M759 HydrophobicContact CE2-CE 3.49Å; F554-M759 VanDerWaalsContact CE2-CE 3.49Å; F554-M759 HydrophobicContact CG-CE 4.19Å; F554-M759 HydrophobicContact CZ-CB 3.82Å; F554-M759 HydrophobicContact CZ-CE 3.78Å; F554-M759 HydrophobicContact CZ-CG 4.22Å
555G94.5Very high95Very high0 Ų046.2 Ų46.20%023%0.229CC..  trans-130.7-150.1176.700000112.5G557 L558 I559 E726 N727G555-G557 PolarHBondContact O-N 2.76Å; G555-G557 VanDerWaalsContact O-N 3.1Å; G555-L558 PolarHBondContact O-N 2.97Å; G555-I559 WeakPolarHBondContact O-CG1 3.5Å; G555-I559 PolarHBondContact O-N 3.17Å; G555-E726 CarbonylContact C-O 3.51Å; G555-E726 VanDerWaalsContact CA-O 3.23Å; G555-E726 WeakPolarHBondContact CA-O 3.36Å; G555-E726 PolarHBondContact N-O 3.17Å; G555-E726 VanDerWaalsContact N-O 3.14Å; G555-N727 VanDerWaalsContact N-CA 3.28Å; G555-N727 PolarHBondContact N-O 3.36Å
556K93.4Very high95Very high49 Ų4946 Ų4621%0.21323%0.229CC..Hα-helixtrans-62.1-23-17676.3-153.9169.4-162.10113.5K560 P566 I723 L724 D725 E726K556-K560 VanDerWaalsContact O-CB 3.32Å; K556-K560 WeakPolarHBondContact O-CB 3.4Å; K556-K560 WeakPolarHBondContact O-CG 3.39Å; K556-K560 PolarHBondContact O-N 2.78Å; K556-P566 HydrophobicContact CB-CB 4.21Å; K556-P566 HydrophobicContact CB-CG 3.95Å; K556-I723 HydrophobicContact CB-CG2 3.7Å; K556-I723 HydrophobicContact CD-CG2 3.96Å; K556-I723 HydrophobicContact CG-CG2 4.39Å; K556-L724 PolarHBondContact NZ-O 2.94Å; K556-L724 VanDerWaalsContact NZ-O 3.11Å; K556-D725 WeakPolarHBondContact CD-O 3.44Å; K556-D725 VanDerWaalsContact CG-O 3.25Å; K556-D725 WeakPolarHBondContact CG-O 3.25Å; K556-D725 PolarHBondContact N-O 3.3Å; K556-E726 VanDerWaalsContact CE-OE1 3.31Å; K556-E726 WeakPolarHBondContact CE-OE1 3.09Å
557G93.9Very high94.9Very high11 Ų1146.4 Ų46.411%0.11323%0.231CC..Hα-helixtrans-67.5-46.7-176.800000112.2G555 K561 E726G555-G557 PolarHBondContact O-N 2.76Å; G555-G557 VanDerWaalsContact O-N 3.1Å; G557-K561 WeakPolarHBondContact O-CG 3.39Å; G557-E726 WeakPolarHBondContact CA-OE2 3.16Å; G557-E726 PolarHBondContact N-O 2.88Å; G557-E726 PolarHBondContact N-OE2 2.94Å
558L95.2Very high94.9Very high68 Ų6846.3 Ų46.336%0.35623%0.231SC..Hα-helixtrans-72.4-42.4176.5-170.159.5000111.4F554 G555 K560 K561 M759F554-L558 HydrophobicContact CB-CB 3.93Å; F554-L558 HydrophobicContact CB-CD2 3.74Å; F554-L558 HydrophobicContact CB-CG 4.48Å; F554-L558 HydrophobicContact CD1-CD2 4.23Å; F554-L558 HydrophobicContact CG-CB 4.44Å; F554-L558 HydrophobicContact CG-CD2 3.97Å; G555-L558 PolarHBondContact O-N 2.97Å; L558-K560 VanDerWaalsContact C-N 3.32Å; L558-K560 PolarHBondContact O-N 3.3Å; L558-K561 HydrophobicContact CD1-CD 4.27Å; L558-K561 WeakPolarHBondContact O-CB 3.28Å; L558-K561 PolarHBondContact O-N 2.87Å; L558-M759 HydrophobicContact CB-CE 4.26Å; L558-M759 HydrophobicContact CD2-CE 3.93Å; L558-M759 HydrophobicContact CD2-CG 3.78Å; L558-M759 HydrophobicContact CD2-SD 3.69Å; L558-M759 HydrophobicContact CG-CE 3.8Å; L558-M759 HydrophobicContact CG-CG 4.45Å; L558-M759 HydrophobicContact CG-SD 3.69Å
559I96.3Very high95Very high0 Ų046.3 Ų46.30%023%0.231CC..Hα-helixtrans-59.4-42.9179.1-60.1164.8000111.2F554 G555 K561 T562 P566 F569 I729 M755 M759F554-I559 HydrophobicContact CD2-CD1 4.27Å; F554-I559 HydrophobicContact CD2-CG1 3.98Å; F554-I559 HydrophobicContact CE2-CD1 4.06Å; F554-I559 HydrophobicContact CE2-CG1 3.86Å; G555-I559 WeakPolarHBondContact O-CG1 3.5Å; G555-I559 PolarHBondContact O-N 3.17Å; I559-K561 PolarHBondContact O-N 2.88Å; I559-T562 WeakPolarHBondContact O-CB 3.19Å; I559-T562 PolarHBondContact O-N 3.06Å; I559-T562 PolarHBondContact O-OG1 3.38Å; I559-P566 HydrophobicContact CD1-CB 4.47Å; I559-P566 HydrophobicContact CG2-CB 4.39Å; I559-P566 HydrophobicContact CG2-CG 4.38Å; I559-F569 HydrophobicContact CD1-CB 4.46Å; I559-F569 HydrophobicContact CD1-CD1 3.96Å; I559-F569 HydrophobicContact CD1-CE1 4.47Å; I559-F569 HydrophobicContact CD1-CG 4.22Å; I559-F569 HydrophobicContact CG1-CD1 4.15Å; I559-F569 HydrophobicContact CG1-CD2 4.37Å; I559-F569 HydrophobicContact CG1-CE1 4.41Å; I559-F569 HydrophobicContact CG1-CG 4.15Å; I559-F569 HydrophobicContact CG2-CB 3.63Å; I559-F569 HydrophobicContact CG2-CD2 3.8Å; I559-F569 HydrophobicContact CG2-CG 3.76Å; I559-I729 HydrophobicContact CD1-CD1 4.14Å; I559-M755 HydrophobicContact CD1-CE 4.49Å; I559-M759 HydrophobicContact CG1-CE 3.85Å
560K94.1Very high95.2Very high118 Ų11845.9 Ų45.951%0.51323%0.229SC..Hα-helixtrans-63.1-30177.8-75.4173-177.8178.50113.1K556 L558 T562 K563 P566K556-K560 VanDerWaalsContact O-CB 3.32Å; K556-K560 WeakPolarHBondContact O-CB 3.4Å; K556-K560 WeakPolarHBondContact O-CG 3.39Å; K556-K560 PolarHBondContact O-N 2.78Å; L558-K560 VanDerWaalsContact C-N 3.32Å; L558-K560 PolarHBondContact O-N 3.3Å; K560-T562 PolarHBondContact O-N 2.84Å; K560-K563 PolarHBondContact O-N 3.37Å; K560-P566 HydrophobicContact CG-CG 3.94Å
561K94.5Very high95.3Very high171 Ų17144.3 Ų44.374%0.74322%0.221SC*.Hα-helixtrans-65.9-23.4175.6-67.5172.2-174.9175.70112.3G557 L558 I559 K563G557-K561 WeakPolarHBondContact O-CG 3.39Å; L558-K561 HydrophobicContact CD1-CD 4.27Å; L558-K561 WeakPolarHBondContact O-CB 3.28Å; L558-K561 PolarHBondContact O-N 2.87Å; I559-K561 PolarHBondContact O-N 2.88Å; K561-K563 PolarHBondContact O-N 3Å
562T92.5Very high95.5Very high14 Ų1444.2 Ų44.29%0.08622%0.221CC..THydrogen-bonded Turntrans-78.7-2.7174.279.20000113.2I559 K560 T564 M759 F762I559-T562 WeakPolarHBondContact O-CB 3.19Å; I559-T562 PolarHBondContact O-N 3.06Å; I559-T562 PolarHBondContact O-OG1 3.38Å; K560-T562 PolarHBondContact O-N 2.84Å; T562-T564 PolarHBondContact O-N 3.25Å; T562-T564 WeakPolarHBondContact OG1-CB 3.47Å; T562-T564 PolarHBondContact OG1-N 3.4Å; T562-T564 PolarHBondContact OG1-OG1 2.77Å; T562-T564 VanDerWaalsContact OG1-OG1 3.12Å; T562-M759 HydrophobicContact CG2-CE 4.35Å; T562-M759 HydrophobicContact CG2-SD 3.88Å; T562-F762 VanDerWaalsContact CB-CE1 3.44Å; T562-F762 HydrophobicContact CG2-CB 4.18Å; T562-F762 HydrophobicContact CG2-CD1 3.85Å; T562-F762 HydrophobicContact CG2-CD2 3.72Å; T562-F762 HydrophobicContact CG2-CE1 4.08Å; T562-F762 HydrophobicContact CG2-CE2 3.98Å; T562-F762 HydrophobicContact CG2-CG 3.64Å; T562-F762 HydrophobicContact CG2-CZ 4.14Å
563K91.6Very high95.7Very high203 Ų20338.8 Ų38.888%0.88319%0.192SC*.THydrogen-bonded Turntrans61.227.9-172.1-54.4-179.7178.7177.90113.2K560 K561K560-K563 PolarHBondContact O-N 3.37Å; K561-K563 PolarHBondContact O-N 3Å
564T93.6Very high95.8Very high11 Ų1134.4 Ų34.47%0.06717%0.165CC..  trans-106.8142.6174.5-54.20000109.9T562 F569 A637T562-T564 PolarHBondContact O-N 3.25Å; T562-T564 WeakPolarHBondContact OG1-CB 3.47Å; T562-T564 PolarHBondContact OG1-N 3.4Å; T562-T564 PolarHBondContact OG1-OG1 2.77Å; T562-T564 VanDerWaalsContact OG1-OG1 3.12Å; T564-F569 HydrophobicContact CG2-CB 4.03Å; T564-F569 HydrophobicContact CG2-CD2 4.3Å; T564-A637 HydrophobicContact CG2-CB 3.88Å
565S94.3Very high95.9Very high35 Ų3534.1 Ų34.125%0.24516%0.164CC..  trans-62.2129.9170.4173.70000109.5D567 A568 F569 Q641S565-D567 PolarHBondContact O-N 3.08Å; S565-A568 PolarHBondContact O-N 2.51Å; S565-F569 WeakPolarHBondContact O-CB 3.48Å; S565-F569 PolarHBondContact O-N 3.05Å; S565-Q641 VanDerWaalsContact CB-CD 3.45Å; S565-Q641 PolarHBondContact OG-NE2 2.94Å
566P96.2Very high96.1Very high19 Ų1934.1 Ų34.112%0.12316%0.164CC..Hα-helixtrans-54.4-39.9178.4-28.736.4000113.9K556 I559 K560 F569 V570 I723K556-P566 HydrophobicContact CB-CB 4.21Å; K556-P566 HydrophobicContact CB-CG 3.95Å; I559-P566 HydrophobicContact CD1-CB 4.47Å; I559-P566 HydrophobicContact CG2-CB 4.39Å; I559-P566 HydrophobicContact CG2-CG 4.38Å; K560-P566 HydrophobicContact CG-CG 3.94Å; P566-F569 WeakPolarHBondContact O-CB 3.43Å; P566-F569 PolarHBondContact O-N 2.92Å; P566-V570 WeakPolarHBondContact O-CG2 3.4Å; P566-V570 PolarHBondContact O-N 3.36Å; P566-V570 VanDerWaalsContact O-N 3.08Å; P566-I723 HydrophobicContact CB-CD1 3.6Å
567D95.9Very high96.4Very high11 Ų1131.8 Ų31.86%0.05915%0.154CC..Hα-helixtrans-67.4-48.3178.8-177.260.3000111.8S565 F569 V570 Q571 H640 Y721S565-D567 PolarHBondContact O-N 3.08Å; D567-F569 VanDerWaalsContact C-N 3.26Å; D567-F569 PolarHBondContact O-N 2.81Å; D567-V570 PolarHBondContact O-N 3.04Å; D567-V570 VanDerWaalsContact O-N 3.16Å; D567-Q571 WeakPolarHBondContact O-CG 3.41Å; D567-Q571 PolarHBondContact O-N 3.01Å; D567-H640 IonicContact OD2-NE2 2.86Å; D567-Y721 PolarHBondContact OD1-OH 2.84Å
568A97.5Very high96.6Very high0 Ų031.6 Ų31.60%015%0.149CC..Hα-helixtrans-60.9-35.5174.700000112.6S565 L572 A637 H640 Q641S565-A568 PolarHBondContact O-N 2.51Å; A568-L572 WeakPolarHBondContact O-CB 3.16Å; A568-L572 WeakPolarHBondContact O-CG 3.25Å; A568-L572 PolarHBondContact O-N 2.87Å; A568-A637 HydrophobicContact CB-CB 4.34Å; A568-H640 HydrophobicContact CB-CB 4.42Å; A568-Q641 HydrophobicContact CB-CG 4.08Å
569F98.5Very high96.8Very high0 Ų031.3 Ų31.30%014%0.144CC..Hα-helixtrans-62.5-48.6176-173.6-77.6000110.9F554 I559 T564 S565 P566 D567 L572 A573 M755 I758 M759 F762F554-F569 AromaticContact CE2-CE1 3.99Å; F554-F569 HydrophobicContact CE2-CE1 3.99Å; F554-F569 HydrophobicContact CE2-CZ 4.28Å; F554-F569 HydrophobicContact CZ-CE1 4.07Å; F554-F569 HydrophobicContact CZ-CZ 4.2Å; I559-F569 HydrophobicContact CD1-CB 4.46Å; I559-F569 HydrophobicContact CD1-CD1 3.96Å; I559-F569 HydrophobicContact CD1-CE1 4.47Å; I559-F569 HydrophobicContact CD1-CG 4.22Å; I559-F569 HydrophobicContact CG1-CD1 4.15Å; I559-F569 HydrophobicContact CG1-CD2 4.37Å; I559-F569 HydrophobicContact CG1-CE1 4.41Å; I559-F569 HydrophobicContact CG1-CG 4.15Å; I559-F569 HydrophobicContact CG2-CB 3.63Å; I559-F569 HydrophobicContact CG2-CD2 3.8Å; I559-F569 HydrophobicContact CG2-CG 3.76Å; T564-F569 HydrophobicContact CG2-CB 4.03Å; T564-F569 HydrophobicContact CG2-CD2 4.3Å; S565-F569 WeakPolarHBondContact O-CB 3.48Å; S565-F569 PolarHBondContact O-N 3.05Å; P566-F569 WeakPolarHBondContact O-CB 3.43Å; P566-F569 PolarHBondContact O-N 2.92Å; D567-F569 VanDerWaalsContact C-N 3.26Å; D567-F569 PolarHBondContact O-N 2.81Å; F569-L572 PolarHBondContact O-N 2.89Å; F569-A573 WeakPolarHBondContact O-CB 3.46Å; F569-A573 PolarHBondContact O-N 2.99Å; F569-M755 HydrophobicContact CD1-CE 4.01Å; F569-M755 HydrophobicContact CD1-SD 3.83Å; F569-M755 HydrophobicContact CE1-CE 3.87Å; F569-M755 HydrophobicContact CE1-SD 3.68Å; F569-I758 HydrophobicContact CD2-CG2 4.11Å; F569-I758 HydrophobicContact CE1-CB 4.46Å; F569-I758 HydrophobicContact CE1-CG2 4.33Å; F569-I758 HydrophobicContact CE2-CB 4.2Å; F569-I758 HydrophobicContact CE2-CG2 3.37Å; F569-I758 HydrophobicContact CZ-CB 3.79Å; F569-I758 HydrophobicContact CZ-CG2 3.49Å; F569-I758 VanDerWaalsContact CZ-CG2 3.49Å; F569-M759 HydrophobicContact CE2-CE 4.03Å; F569-M759 HydrophobicContact CZ-CB 4.36Å; F569-M759 HydrophobicContact CZ-CE 3.87Å; F569-F762 HydrophobicContact CE2-CE2 4.41Å
570V98.6Very high96.8Very high1 Ų133.8 Ų33.81%0.00615%0.153CC..Hα-helixtrans-61.4-48.2177.6172.70000110.2P566 D567 L572 A573 L574 Y721 I729 F731 M755P566-V570 WeakPolarHBondContact O-CG2 3.4Å; P566-V570 PolarHBondContact O-N 3.36Å; P566-V570 VanDerWaalsContact O-N 3.08Å; D567-V570 PolarHBondContact O-N 3.04Å; D567-V570 VanDerWaalsContact O-N 3.16Å; V570-L572 VanDerWaalsContact C-N 3.31Å; V570-L572 PolarHBondContact O-N 3.44Å; V570-A573 CarbonylContact O-C 3.57Å; V570-A573 WeakPolarHBondContact O-CA 3.46Å; V570-A573 WeakPolarHBondContact O-CB 3.46Å; V570-A573 PolarHBondContact O-N 2.99Å; V570-L574 HydrophobicContact CG1-CD1 4.35Å; V570-L574 HydrophobicContact CG1-CG 4.32Å; V570-L574 WeakPolarHBondContact O-CG 3.48Å; V570-L574 PolarHBondContact O-N 2.9Å; V570-Y721 HydrophobicContact CB-CD2 4.48Å; V570-Y721 HydrophobicContact CB-CE2 4.14Å; V570-Y721 HydrophobicContact CG1-CD1 3.88Å; V570-Y721 HydrophobicContact CG1-CD2 3.89Å; V570-Y721 HydrophobicContact CG1-CE1 3.81Å; V570-Y721 HydrophobicContact CG1-CE2 3.82Å; V570-Y721 HydrophobicContact CG1-CG 3.93Å; V570-I729 HydrophobicContact CG2-CD1 3.99Å; V570-F731 HydrophobicContact CG1-CE1 3.72Å; V570-F731 HydrophobicContact CG1-CZ 3.98Å; V570-F731 HydrophobicContact CG2-CZ 4.45Å; V570-M755 HydrophobicContact CG2-CE 4.08Å; V570-M755 HydrophobicContact CG2-SD 4.27Å
571Q98.6Very high96.9Very high0 Ų029.1 Ų29.10%013%0.134CC..Hα-helixtrans-58.2-39.7178.7-74.5-72.8-24.300113D567 L574 Q575 E590 S607 H640 T686 Y721D567-Q571 WeakPolarHBondContact O-CG 3.41Å; D567-Q571 PolarHBondContact O-N 3.01Å; Q571-L574 WeakPolarHBondContact O-CB 3.46Å; Q571-L574 PolarHBondContact O-N 2.81Å; Q571-Q575 WeakPolarHBondContact O-CG 3.31Å; Q571-Q575 PolarHBondContact O-N 3.43Å; Q571-E590 VanDerWaalsContact CD-OE1 3.28Å; Q571-E590 VanDerWaalsContact CG-OE1 3.23Å; Q571-E590 WeakPolarHBondContact CG-OE1 3.13Å; Q571-E590 PolarHBondContact NE2-OE1 3.24Å; Q571-S607 PolarHBondContact OE1-OG 3.01Å; Q571-H640 VanDerWaalsContact CG-CE1 3.47Å; Q571-H640 WeakPolarHBondContact CG-CE1 3.36Å; Q571-T686 PolarHBondContact NE2-OG1 3.4Å; Q571-Y721 PolarHBondContact NE2-OH 3.33Å
572L98.8Very high96.9Very high2 Ų222.3 Ų22.31%0.0111%0.105CC..Hα-helixtrans-71.7-33.5174.9-66.6173000112.9A568 F569 V570 L574 Q575 L576 F615 L633 A636 A637A568-L572 WeakPolarHBondContact O-CB 3.16Å; A568-L572 WeakPolarHBondContact O-CG 3.25Å; A568-L572 PolarHBondContact O-N 2.87Å; F569-L572 PolarHBondContact O-N 2.89Å; V570-L572 VanDerWaalsContact C-N 3.31Å; V570-L572 PolarHBondContact O-N 3.44Å; L572-L574 VanDerWaalsContact C-N 3.32Å; L572-Q575 PolarHBondContact O-N 3.39Å; L572-L576 PolarHBondContact O-N 3.45Å; L572-F615 HydrophobicContact CB-CE1 4.17Å; L572-F615 HydrophobicContact CD2-CD1 4.47Å; L572-L633 HydrophobicContact CD1-CD1 3.76Å; L572-A636 HydrophobicContact CD1-CB 3.93Å; L572-A636 HydrophobicContact CD2-CB 3.62Å; L572-A636 HydrophobicContact CG-CB 4.46Å; L572-A637 HydrophobicContact CD1-CB 3.84Å
573A98.8Very high97.1Very high0 Ų024.2 Ų24.20%013%0.128CC..Hα-helixtrans-64.1-39170.500000111.3F569 V570 L576 A577 A754 M755 I758F569-A573 WeakPolarHBondContact O-CB 3.46Å; F569-A573 PolarHBondContact O-N 2.99Å; V570-A573 CarbonylContact O-C 3.57Å; V570-A573 WeakPolarHBondContact O-CA 3.46Å; V570-A573 WeakPolarHBondContact O-CB 3.46Å; V570-A573 PolarHBondContact O-N 2.99Å; A573-L576 PolarHBondContact O-N 2.85Å; A573-A577 VanDerWaalsContact O-CB 3.25Å; A573-A577 WeakPolarHBondContact O-CB 3.28Å; A573-A577 PolarHBondContact O-N 3.32Å; A573-A754 HydrophobicContact CB-CB 4.21Å; A573-A754 WeakPolarHBondContact O-CB 3.1Å; A573-M755 HydrophobicContact CB-CG 3.96Å; A573-M755 HydrophobicContact CB-SD 3.43Å; A573-M755 WeakPolarHBondContact CB-SD 3.49Å; A573-I758 HydrophobicContact CB-CD1 3.92Å
574L98.8Very high97.2Very high0 Ų018.4 Ų18.40%010%0.102CC..Hα-helixtrans-63.9-40.9173.9-63.6-179.3000111.7V570 Q571 L572 A577 H578 L684 T686 V719 Y721 I751V570-L574 HydrophobicContact CG1-CD1 4.35Å; V570-L574 HydrophobicContact CG1-CG 4.32Å; V570-L574 WeakPolarHBondContact O-CG 3.48Å; V570-L574 PolarHBondContact O-N 2.9Å; Q571-L574 WeakPolarHBondContact O-CB 3.46Å; Q571-L574 PolarHBondContact O-N 2.81Å; L572-L574 VanDerWaalsContact C-N 3.32Å; L574-A577 PolarHBondContact O-N 2.96Å; L574-H578 VanDerWaalsContact O-CB 3.23Å; L574-H578 WeakPolarHBondContact O-CB 3.36Å; L574-H578 PolarHBondContact O-N 3.05Å; L574-L684 HydrophobicContact CB-CD2 4.34Å; L574-T686 HydrophobicContact CD1-CG2 3.85Å; L574-V719 HydrophobicContact CD1-CG1 4.2Å; L574-V719 HydrophobicContact CD2-CG1 4.06Å; L574-Y721 HydrophobicContact CD1-CD1 4.49Å; L574-Y721 HydrophobicContact CD1-CE1 4.19Å; L574-I751 HydrophobicContact CD2-CD1 3.6Å; L574-I751 HydrophobicContact CD2-CG1 3.74Å; L574-I751 HydrophobicContact CD2-CG2 4.19Å
575Q98.8Very high97.4Very high4 Ų419.1 Ų19.12%0.01911%0.105CC..Hα-helixtrans-61.3-44.3174.1-67.8-56.8-70.300112.1Q571 L572 H578 Y579 T588 C608 V616Q571-Q575 WeakPolarHBondContact O-CG 3.31Å; Q571-Q575 PolarHBondContact O-N 3.43Å; L572-Q575 PolarHBondContact O-N 3.39Å; Q575-H578 PolarHBondContact O-N 3.48Å; Q575-Y579 WeakPolarHBondContact O-CB 3.36Å; Q575-Y579 PolarHBondContact O-N 3.4Å; Q575-Y579 VanDerWaalsContact O-N 3.07Å; Q575-T588 PolarHBondContact NE2-OG1 3.32Å; Q575-C608 VanDerWaalsContact OE1-CA 3.3Å; Q575-C608 VanDerWaalsContact OE1-CB 3.27Å; Q575-C608 PolarHBondContact OE1-SG 2.84Å; Q575-C608 VanDerWaalsContact OE1-SG 3.38Å; Q575-V616 HydrophobicContact CB-CG2 3.99Å
576L98.9Very high97.5Very high0 Ų017.9 Ų17.90%010%0.096CC..Hα-helixtrans-65.4-46.9177.5178.758.9000111.7L572 A573 H578 Y579 R580 V616 M619 E620 A754 I758L572-L576 PolarHBondContact O-N 3.45Å; A573-L576 PolarHBondContact O-N 2.85Å; L576-H578 VanDerWaalsContact C-N 3.31Å; L576-H578 PolarHBondContact O-N 3.38Å; L576-Y579 PolarHBondContact O-N 2.75Å; L576-R580 WeakPolarHBondContact O-CG 3.23Å; L576-R580 PolarHBondContact O-N 2.74Å; L576-V616 HydrophobicContact CB-CG2 4.13Å; L576-V616 HydrophobicContact CD1-CG1 4.03Å; L576-V616 HydrophobicContact CD1-CG2 4.47Å; L576-M619 HydrophobicContact CD1-CB 3.81Å; L576-M619 HydrophobicContact CD1-CG 4.49Å; L576-M619 HydrophobicContact CD2-CB 4.28Å; L576-M619 HydrophobicContact CD2-CE 3.93Å; L576-M619 HydrophobicContact CD2-CG 4.23Å; L576-E620 HydrophobicContact CD1-CG 4.22Å; L576-A754 HydrophobicContact CB-CB 4.13Å; L576-A754 HydrophobicContact CD2-CB 3.96Å; L576-A754 HydrophobicContact CG-CB 4.05Å; L576-I758 HydrophobicContact CD2-CD1 4.11Å; L576-I758 HydrophobicContact CD2-CG1 3.96Å
577A98.8Very high97.5Very high0 Ų017.4 Ų17.40%09%0.092CC..Hα-helixtrans-59.3-43.7177.300000111.2A573 L574 R580 D581 F747 N750 I751 A754A573-A577 VanDerWaalsContact O-CB 3.25Å; A573-A577 WeakPolarHBondContact O-CB 3.28Å; A573-A577 PolarHBondContact O-N 3.32Å; L574-A577 PolarHBondContact O-N 2.96Å; A577-R580 PolarHBondContact O-N 3Å; A577-D581 WeakPolarHBondContact O-CB 3.29Å; A577-D581 PolarHBondContact O-N 2.91Å; A577-F747 HydrophobicContact CB-CD2 4.3Å; A577-F747 HydrophobicContact CB-CE2 3.71Å; A577-N750 HydrophobicContact CB-CB 4.02Å; A577-I751 HydrophobicContact CB-CB 4.46Å; A577-I751 HydrophobicContact CB-CG1 3.85Å; A577-A754 HydrophobicContact CB-CB 4.06Å
578H98.4Very high97.6Very high6 Ų617 Ų173%0.0289%0.09CC..Hα-helixtrans-66.9-41.7-177.9-179.3-75.8000110.7L574 Q575 L576 R580 D581 M582 K584 S586 L684 F747L574-H578 VanDerWaalsContact O-CB 3.23Å; L574-H578 WeakPolarHBondContact O-CB 3.36Å; L574-H578 PolarHBondContact O-N 3.05Å; Q575-H578 PolarHBondContact O-N 3.48Å; L576-H578 VanDerWaalsContact C-N 3.31Å; L576-H578 PolarHBondContact O-N 3.38Å; H578-R580 VanDerWaalsContact C-N 3.35Å; H578-R580 PolarHBondContact O-N 2.99Å; H578-D581 PolarHBondContact O-N 3.31Å; H578-M582 WeakPolarHBondContact O-CB 3.42Å; H578-M582 PolarHBondContact O-N 3.35Å; H578-K584 PolarHBondContact ND1-O 3.4Å; H578-S586 PolarHBondContact CE1-OG 2.76Å; H578-L684 HydrophobicContact CB-CD2 4.23Å; H578-F747 HydrophobicContact CB-CE2 4.02Å; H578-F747 HydrophobicContact CB-CZ 4.23Å
579Y98.4Very high97.6Very high62 Ų6218.7 Ų18.724%0.24310%0.097CC..Hα-helixtrans-64.3-39.2176.9-173.4-101000112.5Q575 L576 D581 G583 F585 V616 E620Q575-Y579 WeakPolarHBondContact O-CB 3.36Å; Q575-Y579 PolarHBondContact O-N 3.4Å; Q575-Y579 VanDerWaalsContact O-N 3.07Å; L576-Y579 PolarHBondContact O-N 2.75Å; Y579-D581 VanDerWaalsContact C-N 3.29Å; Y579-D581 PolarHBondContact O-N 3.45Å; Y579-G583 WeakPolarHBondContact O-CA 3.24Å; Y579-G583 PolarHBondContact O-N 2.95Å; Y579-F585 HydrophobicContact CD2-CD1 4.02Å; Y579-F585 HydrophobicContact CD2-CD2 4.18Å; Y579-F585 AromaticContact CD2-CE1 3.67Å; Y579-F585 HydrophobicContact CD2-CE1 3.67Å; Y579-F585 AromaticContact CD2-CE2 3.83Å; Y579-F585 HydrophobicContact CD2-CE2 3.83Å; Y579-F585 HydrophobicContact CD2-CG 4.26Å; Y579-F585 AromaticContact CD2-CZ 3.56Å; Y579-F585 HydrophobicContact CD2-CZ 3.56Å; Y579-F585 HydrophobicContact CE2-CD2 4.12Å; Y579-F585 HydrophobicContact CE2-CE1 4.31Å; Y579-F585 AromaticContact CE2-CE2 3.63Å; Y579-F585 HydrophobicContact CE2-CE2 3.63Å; Y579-F585 AromaticContact CE2-CZ 3.74Å; Y579-F585 HydrophobicContact CE2-CZ 3.74Å; Y579-F585 HydrophobicContact CG-CE1 4.12Å; Y579-F585 HydrophobicContact CG-CZ 4.16Å; Y579-V616 VanDerWaalsContact CB-CG1 3.45Å; Y579-V616 HydrophobicContact CD1-CG1 3.55Å; Y579-V616 HydrophobicContact CD2-CG1 4.33Å; Y579-V616 HydrophobicContact CE1-CG1 4.39Å; Y579-V616 HydrophobicContact CG-CG1 3.5Å; Y579-E620 HydrophobicContact CD1-CG 4.07Å; Y579-E620 HydrophobicContact CE1-CG 4.21Å
580R97.8Very high97.6Very high52 Ų5218.7 Ų18.720%0.19610%0.097CC..Hα-helixtrans-64.4-34.7173.5-74.4171.3173.5-177.9-5.8113L576 A577 H578 E620 D757L576-R580 WeakPolarHBondContact O-CG 3.23Å; L576-R580 PolarHBondContact O-N 2.74Å; A577-R580 PolarHBondContact O-N 3Å; H578-R580 VanDerWaalsContact C-N 3.35Å; H578-R580 PolarHBondContact O-N 2.99Å; R580-E620 IonicContact CZ-OE1 3.67Å; R580-E620 IonicContact NE-OE1 3.72Å; R580-E620 PolarHBondContact NE-OE1 2.76Å; R580-E620 IonicContact NE-OE2 3.06Å; R580-E620 IonicContact NH2-OE1 3.57Å; R580-E620 PolarHBondContact NH2-OE1 3.35Å; R580-D757 IonicContact CZ-OD2 3.42Å; R580-D757 IonicContact NH1-OD2 3.22Å; R580-D757 PolarHBondContact NH1-OD2 2.6Å; R580-D757 IonicContact NH2-OD2 2.75Å; R580-D757 PolarHBondContact NH2-OD2 2.95Å
581D96.7Very high97.5Very high20 Ų2020 Ų2011%0.10711%0.108CC..Hα-helixtrans-78.4-45.2-177.7-161.873.8000112.4A577 H578 Y579 Y717 R746 F747 N750A577-D581 WeakPolarHBondContact O-CB 3.29Å; A577-D581 PolarHBondContact O-N 2.91Å; H578-D581 PolarHBondContact O-N 3.31Å; Y579-D581 VanDerWaalsContact C-N 3.29Å; Y579-D581 PolarHBondContact O-N 3.45Å; D581-Y717 PolarHBondContact OD2-OH 3.23Å; D581-R746 VanDerWaalsContact CG-NH2 3.35Å; D581-R746 IonicContact OD1-CZ 3.31Å; D581-R746 IonicContact OD1-NE 3.53Å; D581-R746 PolarHBondContact OD1-NE 3.01Å; D581-R746 IonicContact OD1-NH2 3.08Å; D581-R746 PolarHBondContact OD1-NH2 2.67Å; D581-R746 IonicContact OD2-CZ 2.7Å; D581-R746 IonicContact OD2-NE 3.67Å; D581-R746 IonicContact OD2-NH2 2.64Å; D581-R746 PolarHBondContact OD2-NH2 3.48Å; D581-F747 HydrophobicContact CB-CD2 4.08Å; D581-N750 PolarHBondContact OD1-ND2 2.95Å
582M94.6Very high97.3Very high28 Ų2820 Ų2014%0.13811%0.108CC..Hα-helixtrans-105.3-13.5-169.8-69.1-71.3-167.400114.3H578 K584 Y717 E741 T742H578-M582 WeakPolarHBondContact O-CB 3.42Å; H578-M582 PolarHBondContact O-N 3.35Å; M582-K584 HydrophobicContact CB-CG 4.13Å; M582-K584 PolarHBondContact O-N 2.88Å; M582-K584 VanDerWaalsContact O-N 3.07Å; M582-Y717 HydrophobicContact CE-CD2 4.27Å; M582-Y717 HydrophobicContact CE-CE2 3.46Å; M582-Y717 VanDerWaalsContact CE-CE2 3.46Å; M582-E741 HydrophobicContact CE-CB 4.21Å; M582-E741 WeakPolarHBondContact CE-O 3.43Å; M582-E741 HydrophobicContact SD-CB 4.08Å; M582-T742 HydrophobicContact CE-CG2 3.4Å
583G95.1Very high97.1Very high54 Ų5422.3 Ų22.356%0.55712%0.119SC*.SBendtrans67.13.2-174.800000115.1Y579Y579-G583 WeakPolarHBondContact O-CA 3.24Å; Y579-G583 PolarHBondContact O-N 2.95Å
584K95Very high97Very high81 Ų8122.6 Ų22.635%0.35212%0.121SC..SBendtrans-138.9154.7-176.166.5-168.1171.7-163.40111.9H578 M582 E741H578-K584 PolarHBondContact ND1-O 3.4Å; M582-K584 HydrophobicContact CB-CG 4.13Å; M582-K584 PolarHBondContact O-N 2.88Å; M582-K584 VanDerWaalsContact O-N 3.07Å; K584-E741 IonicContact NZ-OE2 3.27Å; K584-E741 PolarHBondContact NZ-OE2 3.25Å
585F97Very high96.9Very high27 Ų2723 Ų2312%0.11812%0.123CC..  trans-81.2148.4168.7-65.3-67.4000109.9L193 Y579 C613 V616 R617L193-F585 HydrophobicContact CD2-CB 4.2Å; Y579-F585 HydrophobicContact CD2-CD1 4.02Å; Y579-F585 HydrophobicContact CD2-CD2 4.18Å; Y579-F585 AromaticContact CD2-CE1 3.67Å; Y579-F585 HydrophobicContact CD2-CE1 3.67Å; Y579-F585 AromaticContact CD2-CE2 3.83Å; Y579-F585 HydrophobicContact CD2-CE2 3.83Å; Y579-F585 HydrophobicContact CD2-CG 4.26Å; Y579-F585 AromaticContact CD2-CZ 3.56Å; Y579-F585 HydrophobicContact CD2-CZ 3.56Å; Y579-F585 HydrophobicContact CE2-CD2 4.12Å; Y579-F585 HydrophobicContact CE2-CE1 4.31Å; Y579-F585 AromaticContact CE2-CE2 3.63Å; Y579-F585 HydrophobicContact CE2-CE2 3.63Å; Y579-F585 AromaticContact CE2-CZ 3.74Å; Y579-F585 HydrophobicContact CE2-CZ 3.74Å; Y579-F585 HydrophobicContact CG-CE1 4.12Å; Y579-F585 HydrophobicContact CG-CZ 4.16Å; F585-C613 HydrophobicContact CD1-CB 4.27Å; F585-C613 WeakPolarHBondContact CD1-SG 3.41Å; F585-C613 HydrophobicContact CD2-CB 4.3Å; F585-C613 HydrophobicContact CE1-CB 3.9Å; F585-C613 HydrophobicContact CE2-CB 3.94Å; F585-C613 HydrophobicContact CG-CB 4.47Å; F585-C613 VanDerWaalsContact CG-SG 3.59Å; F585-C613 HydrophobicContact CZ-CB 3.72Å; F585-V616 HydrophobicContact CE1-CB 3.93Å; F585-V616 HydrophobicContact CE1-CG1 3.8Å; F585-V616 HydrophobicContact CE1-CG2 4.45Å; F585-V616 HydrophobicContact CZ-CB 4.14Å; F585-V616 HydrophobicContact CZ-CG1 3.96Å; F585-R617 HydrophobicContact CE2-CG 4.29Å; F585-R617 HydrophobicContact CZ-CG 4.15Å
586S95.6Very high96.8Very high8 Ų823.1 Ų23.16%0.05612%0.123CC..  trans-145.6153-178.8-69.70000111.2H578 T588 C608H578-S586 PolarHBondContact CE1-OG 2.76Å; S586-T588 PolarHBondContact O-N 3.31Å; S586-T588 VanDerWaalsContact O-N 3.13Å; S586-T588 PolarHBondContact O-OG1 3.12Å; S586-T588 VanDerWaalsContact O-OG1 3.09Å; S586-C608 VanDerWaalsContact O-CB 3.32Å; S586-C608 WeakPolarHBondContact O-CB 3.24Å
587L96.1Very high96.7Very high10 Ų1023.3 Ų23.35%0.05212%0.124CC..  trans-59120.1179.1-171.568000109.4L193 E680 W682 R683 L684L193-L587 HydrophobicContact CD1-CB 3.95Å; L193-L587 HydrophobicContact CD1-CD1 3.71Å; L193-L587 HydrophobicContact CD1-CG 4.42Å; L587-E680 HydrophobicContact CD2-CB 3.94Å; L587-W682 HydrophobicContact CB-CE3 4.39Å; L587-W682 HydrophobicContact CD1-CE3 4.24Å; L587-W682 HydrophobicContact CD1-CH2 4.13Å; L587-W682 HydrophobicContact CD1-CZ3 3.65Å; L587-W682 HydrophobicContact CD2-CD2 3.8Å; L587-W682 HydrophobicContact CD2-CE3 3.54Å; L587-W682 HydrophobicContact CD2-CH2 3.82Å; L587-W682 HydrophobicContact CD2-CZ2 4.04Å; L587-W682 HydrophobicContact CD2-CZ3 3.58Å; L587-W682 HydrophobicContact CG-CD2 4.15Å; L587-W682 HydrophobicContact CG-CE3 3.39Å; L587-W682 HydrophobicContact CG-CH2 4.02Å; L587-W682 HydrophobicContact CG-CZ3 3.33Å; L587-R683 PolarHBondContact O-N 2.86Å; L587-L684 PolarHBondContact O-N 3.42Å
588T98.3Very high96.6Very high1 Ų126.9 Ų26.91%0.00614%0.137CC..EExtended strand (participates in β ladder)trans-114.1125.5-175.1-56.90000110.3Q575 S586 R606 S607 L684 T686Q575-T588 PolarHBondContact NE2-OG1 3.32Å; S586-T588 PolarHBondContact O-N 3.31Å; S586-T588 VanDerWaalsContact O-N 3.13Å; S586-T588 PolarHBondContact O-OG1 3.12Å; S586-T588 VanDerWaalsContact O-OG1 3.09Å; T588-R606 WeakPolarHBondContact O-CA 3.43Å; T588-S607 PolarHBondContact O-N 2.68Å; T588-L684 CarbonylContact C-O 3.56Å; T588-L684 VanDerWaalsContact CA-O 3.28Å; T588-L684 WeakPolarHBondContact CA-O 3.32Å; T588-L684 HydrophobicContact CG2-CB 4.01Å; T588-L684 HydrophobicContact CG2-CD2 3.73Å; T588-L684 HydrophobicContact CG2-CG 3.81Å; T588-T686 HydrophobicContact CG2-CG2 4.28Å
589Y98.3Very high96.4Very high36 Ų3629.4 Ų29.414%0.14115%0.149CC..EExtended strand (participates in β ladder)trans-96.9130.6175.3179.9-86.8000109.8A591 T604 R655 W682 L684 T686Y589-A591 HydrophobicContact CE1-CB 3.89Å; Y589-T604 HydrophobicContact CD2-CG2 3.29Å; Y589-T604 HydrophobicContact CE2-CG2 3.63Å; Y589-T604 VanDerWaalsContact CE2-OG1 3.23Å; Y589-T604 WeakPolarHBondContact CE2-OG1 3.29Å; Y589-T604 HydrophobicContact CG-CG2 4.09Å; Y589-R655 PolarHBondContact OH-NH2 3.23Å; Y589-R655 VanDerWaalsContact OH-NH2 3.07Å; Y589-W682 VanDerWaalsContact CB-CE3 3.48Å; Y589-W682 HydrophobicContact CD2-CD2 4.16Å; Y589-W682 HydrophobicContact CD2-CE3 4.33Å; Y589-W682 HydrophobicContact CD2-CZ2 4.43Å; Y589-W682 HydrophobicContact CG-CD2 4.44Å; Y589-W682 HydrophobicContact CG-CE3 4.42Å; Y589-L684 PolarHBondContact N-O 3.24Å; Y589-T686 WeakPolarHBondContact O-CA 3.45Å; Y589-T686 WeakPolarHBondContact O-CB 3.34Å; Y589-T686 PolarHBondContact O-N 2.81Å; Y589-T686 PolarHBondContact O-OG1 3.49Å
590E98.4Very high96.3Very high1 Ų126.5 Ų26.51%0.00514%0.138CC..EExtended strand (participates in β ladder)trans-125132.1160.9173.7-175.4-129.400110.1Q571 S592 V605 H640 T686 Y721Q571-E590 VanDerWaalsContact CD-OE1 3.28Å; Q571-E590 VanDerWaalsContact CG-OE1 3.23Å; Q571-E590 WeakPolarHBondContact CG-OE1 3.13Å; Q571-E590 PolarHBondContact NE2-OE1 3.24Å; E590-S592 PolarHBondContact O-N 3.39Å; E590-V605 HydrophobicContact CB-CB 4.06Å; E590-V605 HydrophobicContact CG-CB 4.46Å; E590-V605 PolarHBondContact N-O 3.29Å; E590-V605 PolarHBondContact O-N 3.08Å; E590-V605 WeakPolarHBondContact OE2-CB 3.49Å; E590-V605 WeakPolarHBondContact OE2-CG1 3.43Å; E590-H640 IonicContact OE1-NE2 3.44Å; E590-H640 IonicContact OE2-CE1 2.77Å; E590-H640 PolarHBondContact OE2-CE1 3.08Å; E590-H640 IonicContact OE2-NE2 3.5Å; E590-H640 PolarHBondContact OE2-NE2 3.35Å; E590-T686 WeakPolarHBondContact CA-O 3.28Å; E590-T686 WeakPolarHBondContact CA-OG1 3.49Å; E590-T686 WeakPolarHBondContact CB-OG1 3.41Å; E590-Y721 PolarHBondContact OE1-OH 3.46Å
591A96.2Very high96.1Very high29 Ų2924.9 Ų24.924%0.2413%0.132CC..EExtended strand (participates in β ladder)trans-73122.8175.900000111.6Y589 T686Y589-A591 HydrophobicContact CE1-CB 3.89Å; A591-T686 PolarHBondContact N-O 3.14Å
592S95.5Very high96.1Very high0 Ų024.7 Ų24.70%013%0.131CC..EExtended strand (participates in β ladder)trans-118.7133170.6-173.90000110.9E590 T602 E603 M648E590-S592 PolarHBondContact O-N 3.39Å; S592-T602 CarbonylContact O-C 3.59Å; S592-T602 WeakPolarHBondContact O-CA 3.45Å; S592-E603 PolarHBondContact N-O 3.47Å; S592-E603 PolarHBondContact O-N 2.89Å; S592-M648 WeakPolarHBondContact OG-CG 3.48Å
593M94Very high96.2Very high50 Ų5023.7 Ų23.725%0.24613%0.126CC..EExtended strand (participates in β ladder)trans-72.4137.6-178.265.5175.3179.600112.4L296 L303 R595 M648L296-M593 HydrophobicContact CD1-CE 4.25Å; L303-M593 HydrophobicContact CD1-CE 3.83Å; L303-M593 HydrophobicContact CD1-SD 3.86Å; L303-M593 HydrophobicContact CD2-CE 4.36Å; M593-R595 HydrophobicContact CB-CG 4.35Å; M593-R595 HydrophobicContact SD-CB 4.48Å; M593-M648 HydrophobicContact CE-CE 3.51Å; M593-M648 HydrophobicContact CG-CE 4.27Å
594T96.3Very high96.4Very high6 Ų621.4 Ų21.44%0.03710%0.102CC..  trans-103.922.3170.253.40000112.2L174 L596 F597 R601 E603L174-T594 HydrophobicContact CD1-CG2 4.31Å; T594-L596 PolarHBondContact O-N 3.09Å; T594-F597 WeakPolarHBondContact O-CD2 3.25Å; T594-F597 PolarHBondContact O-N 3.22Å; T594-R601 PolarHBondContact N-O 3Å; T594-R601 PolarHBondContact OG1-N 3.41Å; T594-R601 PolarHBondContact OG1-O 2.67Å; T594-E603 HydrophobicContact CG2-CB 3.6Å
595R96.4Very high96.5Very high9 Ų917.6 Ų17.63%0.0349%0.085CC..THydrogen-bonded Turntrans-67.5-2.4-176.5-69.4176.560.1-153.6-5114.6L303 C304 M593 F597 G600L303-R595 CarbonylContact C-O 3.54Å; L303-R595 WeakPolarHBondContact CA-O 3.48Å; L303-R595 HydrophobicContact CB-CB 4.13Å; L303-R595 HydrophobicContact CD2-CB 4.25Å; C304-R595 HydrophobicContact CB-CB 4.32Å; C304-R595 WeakPolarHBondContact CB-O 3.47Å; C304-R595 PolarHBondContact N-O 2.86Å; C304-R595 VanDerWaalsContact O-CZ 3.31Å; C304-R595 PolarHBondContact O-NE 3.36Å; C304-R595 PolarHBondContact O-NH2 2.94Å; M593-R595 HydrophobicContact CB-CG 4.35Å; M593-R595 HydrophobicContact SD-CB 4.48Å; R595-F597 PolarHBondContact O-N 3.13Å; R595-G600 WeakPolarHBondContact CG-O 3.17Å
596L96.9Very high96.6Very high5 Ų516.8 Ų16.83%0.0268%0.081CC..THydrogen-bonded Turntrans-63.4-20.5164.5-67174.2000111.8W135 P172 L296 V301 L303 T594 M648W135-L596 HydrophobicContact CZ2-CD2 4.22Å; P172-L596 WeakPolarHBondContact CD-O 3.29Å; P172-L596 WeakPolarHBondContact CG-O 3.17Å; L296-L596 HydrophobicContact CD1-CD2 4.24Å; V301-L596 HydrophobicContact CG1-CD2 3.74Å; L303-L596 HydrophobicContact CD2-CD2 3.82Å; L303-L596 HydrophobicContact CD2-CG 4.34Å; T594-L596 PolarHBondContact O-N 3.09Å; L596-M648 HydrophobicContact CD1-CB 4.35Å; L596-M648 HydrophobicContact CD1-CE 4.19Å
597F97.5Very high96.7Very high4 Ų416.5 Ų16.52%0.0188%0.08CC..SBendtrans-107.1152.1178.7-53.1-76.3000111.4H133 P172 R173 L174 P175 C304 T594 R595 E599 G600 M648 T649H133-F597 AromaticContact CE1-CE1 3.48Å; H133-F597 VanDerWaalsContact CE1-CE1 3.48Å; H133-F597 WeakPolarHBondContact CE1-CE1 3.01Å; H133-F597 AromaticContact CE1-CZ 3.56Å; H133-F597 AromaticContact NE2-CE1 3.98Å; H133-F597 AromaticContact NE2-CZ 3.86Å; P172-F597 HydrophobicContact CB-CD1 4.07Å; P172-F597 HydrophobicContact CB-CE1 4.42Å; P172-F597 HydrophobicContact CG-CD1 3.74Å; P172-F597 HydrophobicContact CG-CE1 4.11Å; P172-F597 WeakPolarHBondContact O-CA 3.38Å; R173-F597 VanDerWaalsContact O-CD1 3.26Å; R173-F597 WeakPolarHBondContact O-CD1 3.19Å; L174-F597 HydrophobicContact CB-CB 4.05Å; L174-F597 HydrophobicContact CB-CD2 4.49Å; L174-F597 HydrophobicContact CB-CG 4.12Å; L174-F597 HydrophobicContact CD1-CB 4.24Å; L174-F597 HydrophobicContact CD1-CD2 3.24Å; L174-F597 HydrophobicContact CD1-CE2 3.63Å; L174-F597 HydrophobicContact CD1-CG 3.74Å; L174-F597 HydrophobicContact CD1-CZ 4.42Å; L174-F597 HydrophobicContact CG-CD2 4.43Å; P175-F597 HydrophobicContact CG-CE1 4.27Å; P175-F597 HydrophobicContact CG-CZ 4.16Å; C304-F597 VanDerWaalsContact CB-O 3.32Å; C304-F597 WeakPolarHBondContact CB-O 3.09Å; T594-F597 WeakPolarHBondContact O-CD2 3.25Å; T594-F597 PolarHBondContact O-N 3.22Å; R595-F597 PolarHBondContact O-N 3.13Å; F597-E599 PolarHBondContact O-N 2.96Å; F597-G600 PolarHBondContact O-N 3.25Å; F597-G600 VanDerWaalsContact O-N 3.08Å; F597-M648 WeakPolarHBondContact CE2-O 3.46Å; F597-T649 WeakPolarHBondContact CZ-O 3.31Å
598R95.9Very high96.8Very high76 Ų7616.2 Ų16.229%0.2878%0.078SC..THydrogen-bonded Turntrans-57.1132.4173.9-175.6176.3175.41570.2110.1Q168 L171 P172 N230 G600Q168-R598 WeakPolarHBondContact O-CD 3.34Å; L171-R598 HydrophobicContact CB-CB 4.04Å; P172-R598 PolarHBondContact O-N 2.93Å; N230-R598 PolarHBondContact ND2-O 3.26Å; R598-G600 PolarHBondContact O-N 3.39Å; R598-G600 VanDerWaalsContact O-N 3.07Å
599E95.3Very high96.8Very high58 Ų5816.5 Ų16.527%0.2718%0.08SC..THydrogen-bonded Turntrans56.618.8-178-67.2154.6-139.100114T229 N230 S233 C304 A306 F597 R601T229-E599 WeakPolarHBondContact CB-OE1 3.45Å; T229-E599 VanDerWaalsContact CB-OE2 3.3Å; T229-E599 WeakPolarHBondContact CB-OE2 3.25Å; T229-E599 VanDerWaalsContact OG1-CD 3.31Å; T229-E599 PolarHBondContact OG1-OE1 3.23Å; T229-E599 PolarHBondContact OG1-OE2 2.84Å; N230-E599 HydrophobicContact CB-CB 4.07Å; S233-E599 PolarHBondContact OG-O 3.02Å; C304-E599 PolarHBondContact SG-N 2.88Å; A306-E599 HydrophobicContact CB-CG 4.02Å; F597-E599 PolarHBondContact O-N 2.96Å; E599-R601 PolarHBondContact O-N 3.27Å
600G95.4Very high96.8Very high1 Ų117.3 Ų17.31%0.019%0.088CC..  trans-62.4131.5175.300000112.3Q307 R595 F597 R598Q307-G600 PolarHBondContact NE2-O 2.94Å; R595-G600 WeakPolarHBondContact CG-O 3.17Å; F597-G600 PolarHBondContact O-N 3.25Å; F597-G600 VanDerWaalsContact O-N 3.08Å; R598-G600 PolarHBondContact O-N 3.39Å; R598-G600 VanDerWaalsContact O-N 3.07Å
601R94.5Very high96.8Very high19 Ų1920 Ų207%0.07210%0.101CC..  trans-103.1-102.5171.4-69.5-74.6-61.5-103.71.3108.1H473 S474 W475 A476 D477 T594 E599H473-R601 PolarHBondContact O-NH2 3.16Å; S474-R601 PolarHBondContact O-NH1 3Å; W475-R601 PolarHBondContact O-NH1 3.1Å; A476-R601 PolarHBondContact O-NH2 2.81Å; D477-R601 IonicContact OD1-CZ 2.71Å; D477-R601 VanDerWaalsContact OD1-CZ 3.23Å; D477-R601 IonicContact OD1-NE 3.29Å; D477-R601 PolarHBondContact OD1-NE 2.95Å; D477-R601 IonicContact OD1-NH2 2.81Å; D477-R601 PolarHBondContact OD1-NH2 2.92Å; D477-R601 WeakPolarHBondContact OD2-CA 3.38Å; D477-R601 WeakPolarHBondContact OD2-CD 3.44Å; D477-R601 IonicContact OD2-NE 2.95Å; D477-R601 PolarHBondContact OD2-NE 3.39Å; D477-R601 VanDerWaalsContact OD2-NE 3.1Å; T594-R601 PolarHBondContact N-O 3Å; T594-R601 PolarHBondContact OG1-N 3.41Å; T594-R601 PolarHBondContact OG1-O 2.67Å; E599-R601 PolarHBondContact O-N 3.27Å
602T95.8Very high97Very high15 Ų1518.7 Ų18.79%0.0929%0.09CC..EExtended strand (participates in β ladder)trans-129.8156-174.355.40000112.2S592 R655S592-T602 CarbonylContact O-C 3.59Å; S592-T602 WeakPolarHBondContact O-CA 3.45Å; T602-R655 WeakPolarHBondContact O-CG 3.3Å; T602-R655 PolarHBondContact O-NE 2.93Å; T602-R655 PolarHBondContact OG1-NH2 3.3Å
603E97.6Very high97.1Very high7 Ų718.7 Ų18.73%0.0339%0.09CC..EExtended strand (participates in β ladder)trans-126.5166.2161.4178.257.4-80.500107.6S592 T594 A647 G652 D654 R655S592-E603 PolarHBondContact N-O 3.47Å; S592-E603 PolarHBondContact O-N 2.89Å; T594-E603 HydrophobicContact CG2-CB 3.6Å; E603-A647 HydrophobicContact CB-CB 4.11Å; E603-A647 HydrophobicContact CG-CB 3.77Å; E603-G652 WeakPolarHBondContact OE2-CA 3.1Å; E603-D654 PolarHBondContact OE1-N 3.39Å; E603-R655 WeakPolarHBondContact OE1-CG 3.45Å; E603-R655 PolarHBondContact OE1-N 3.44Å; E603-R655 IonicContact OE1-NH1 3.69Å
604T97.7Very high97.3Very high7 Ų719.5 Ų19.54%0.04310%0.095CC..EExtended strand (participates in β ladder)trans-96.7132.7-178.9-45.20000111.4Y589 R606 D654 R655 W682Y589-T604 HydrophobicContact CD2-CG2 3.29Å; Y589-T604 HydrophobicContact CE2-CG2 3.63Å; Y589-T604 VanDerWaalsContact CE2-OG1 3.23Å; Y589-T604 WeakPolarHBondContact CE2-OG1 3.29Å; Y589-T604 HydrophobicContact CG-CG2 4.09Å; T604-R606 HydrophobicContact CG2-CG 4.23Å; T604-D654 WeakPolarHBondContact CB-OD2 3.31Å; T604-D654 VanDerWaalsContact OG1-CB 3.27Å; T604-D654 WeakPolarHBondContact OG1-CB 3.37Å; T604-R655 PolarHBondContact OG1-NH1 2.84Å; T604-W682 HydrophobicContact CG2-CH2 3.7Å; T604-W682 HydrophobicContact CG2-CZ2 4.27Å; T604-W682 HydrophobicContact CG2-CZ3 4.02Å
605V98.4Very high97.4Very high1 Ų119.2 Ų19.21%0.0069%0.094CC..EExtended strand (participates in β ladder)trans-99.1120.4160.1175.20000107.5E590 S607 L643 Y644 A647E590-V605 HydrophobicContact CB-CB 4.06Å; E590-V605 HydrophobicContact CG-CB 4.46Å; E590-V605 PolarHBondContact N-O 3.29Å; E590-V605 PolarHBondContact O-N 3.08Å; E590-V605 WeakPolarHBondContact OE2-CB 3.49Å; E590-V605 WeakPolarHBondContact OE2-CG1 3.43Å; V605-S607 PolarHBondContact O-N 3.09Å; V605-L643 HydrophobicContact CG1-CB 4Å; V605-Y644 HydrophobicContact CG2-CD2 3.83Å; V605-Y644 HydrophobicContact CG2-CG 4.3Å; V605-A647 HydrophobicContact CG2-CB 3.75Å
606R98.1Very high97.6Very high9 Ų918.8 Ų18.83%0.0349%0.092CC..EExtended strand (participates in β ladder)trans-86.890.6177.4-65.7-176.6172.9-132-8.4109S189 T588 T604 C608 T609 D654 W682S189-R606 VanDerWaalsContact OG-CD 3.32Å; S189-R606 WeakPolarHBondContact OG-CD 3.32Å; S189-R606 PolarHBondContact OG-NH1 3.3Å; T588-R606 WeakPolarHBondContact O-CA 3.43Å; T604-R606 HydrophobicContact CG2-CG 4.23Å; R606-C608 VanDerWaalsContact C-N 3.28Å; R606-C608 PolarHBondContact O-N 2.86Å; R606-T609 WeakPolarHBondContact O-CG2 3.16Å; R606-D654 IonicContact CZ-OD1 3.38Å; R606-D654 IonicContact CZ-OD2 2.72Å; R606-D654 IonicContact NE-OD1 3.1Å; R606-D654 PolarHBondContact NE-OD1 2.92Å; R606-D654 IonicContact NE-OD2 3.17Å; R606-D654 PolarHBondContact NE-OD2 3.45Å; R606-D654 IonicContact NH2-OD1 3.2Å; R606-D654 PolarHBondContact NH2-OD1 3.34Å; R606-D654 IonicContact NH2-OD2 2.64Å; R606-W682 HydrophobicContact CG-CH2 4.04Å; R606-W682 HydrophobicContact CG-CZ3 4.16Å
607S98Very high97.6Very high3 Ų324.1 Ų24.12%0.02111%0.112CC..  trans-68.2-24.4-171.3-58.30000114.2Q571 T588 V605 T609 S612 H640Q571-S607 PolarHBondContact OE1-OG 3.01Å; T588-S607 PolarHBondContact O-N 2.68Å; V605-S607 PolarHBondContact O-N 3.09Å; S607-T609 PolarHBondContact O-N 3.48Å; S607-T609 VanDerWaalsContact O-N 3.08Å; S607-S612 PolarHBondContact O-OG 2.88Å; S607-H640 PolarHBondContact OG-CE1 3.45Å
608C98.3Very high97.7Very high3 Ų324.1 Ų24.12%0.0211%0.113CC..  trans-79.987175.3-164.40000110.5Q575 S586 R606Q575-C608 VanDerWaalsContact OE1-CA 3.3Å; Q575-C608 VanDerWaalsContact OE1-CB 3.27Å; Q575-C608 PolarHBondContact OE1-SG 2.84Å; Q575-C608 VanDerWaalsContact OE1-SG 3.38Å; S586-C608 VanDerWaalsContact O-CB 3.32Å; S586-C608 WeakPolarHBondContact O-CB 3.24Å; R606-C608 VanDerWaalsContact C-N 3.28Å; R606-C608 PolarHBondContact O-N 2.86Å
609T98.6Very high97.8Very high8 Ų821.4 Ų21.45%0.04910%0.103CC..  trans-105.7164.9177.382.90000111.6R606 S607 E611 S612 C613 K639 L643R606-T609 WeakPolarHBondContact O-CG2 3.16Å; S607-T609 PolarHBondContact O-N 3.48Å; S607-T609 VanDerWaalsContact O-N 3.08Å; T609-E611 VanDerWaalsContact CB-OE2 3.25Å; T609-E611 WeakPolarHBondContact CB-OE2 3.24Å; T609-E611 PolarHBondContact O-N 2.89Å; T609-E611 PolarHBondContact OG1-N 2.63Å; T609-E611 PolarHBondContact OG1-OE2 3.42Å; T609-S612 PolarHBondContact N-OG 3.34Å; T609-S612 PolarHBondContact O-N 3.42Å; T609-S612 VanDerWaalsContact O-N 3.14Å; T609-S612 PolarHBondContact O-OG 3.03Å; T609-S612 PolarHBondContact OG1-N 2.86Å; T609-S612 VanDerWaalsContact OG1-N 3.12Å; T609-C613 PolarHBondContact O-N 3.29Å; T609-C613 PolarHBondContact O-SG 2.83Å; T609-K639 HydrophobicContact CG2-CG 4.12Å; T609-L643 HydrophobicContact CG2-CD1 3.5Å
610V98.5Very high97.9Very high52 Ų5222.4 Ų22.432%0.31511%0.108SC..Hα-helixtrans-53.1-43.7171.6176.20000111.2R191 P192 C613 N614R191-V610 HydrophobicContact CB-CG2 4.23Å; R191-V610 HydrophobicContact CG-CG2 4.31Å; P192-V610 HydrophobicContact CG-CG2 4.38Å; V610-C613 PolarHBondContact O-N 3.42Å; V610-N614 WeakPolarHBondContact O-CB 3.49Å; V610-N614 PolarHBondContact O-N 3.36Å; V610-N614 PolarHBondContact O-ND2 3.39Å; V610-N614 PolarHBondContact O-OD1 2.95Å
611E98.8Very high98Very high58 Ų5825.1 Ų25.127%0.27112%0.123SC..Hα-helixtrans-63.5-43.8178.6-57.785.716300111.8T609 C613 N614 F615 A636 K639T609-E611 VanDerWaalsContact CB-OE2 3.25Å; T609-E611 WeakPolarHBondContact CB-OE2 3.24Å; T609-E611 PolarHBondContact O-N 2.89Å; T609-E611 PolarHBondContact OG1-N 2.63Å; T609-E611 PolarHBondContact OG1-OE2 3.42Å; E611-C613 VanDerWaalsContact C-N 3.35Å; E611-N614 PolarHBondContact O-N 3.13Å; E611-F615 WeakPolarHBondContact O-CB 3.42Å; E611-F615 PolarHBondContact O-N 3.01Å; E611-A636 HydrophobicContact CB-CB 4.2Å; E611-K639 HydrophobicContact CB-CB 4.26Å; E611-K639 HydrophobicContact CG-CB 4.13Å; E611-K639 HydrophobicContact CG-CG 4.3Å; E611-K639 WeakPolarHBondContact OE1-CD 3.18Å; E611-K639 WeakPolarHBondContact OE1-CE 3.43Å; E611-K639 IonicContact OE1-NZ 2.71Å; E611-K639 WeakPolarHBondContact OE2-CG 3.32Å
612S98.7Very high98Very high1 Ų130.3 Ų30.31%0.00716%0.158CC..Hα-helixtrans-63.3-40.6174.974.30000112S607 T609 F615 V616S607-S612 PolarHBondContact O-OG 2.88Å; T609-S612 PolarHBondContact N-OG 3.34Å; T609-S612 PolarHBondContact O-N 3.42Å; T609-S612 VanDerWaalsContact O-N 3.14Å; T609-S612 PolarHBondContact O-OG 3.03Å; T609-S612 PolarHBondContact OG1-N 2.86Å; T609-S612 VanDerWaalsContact OG1-N 3.12Å; S612-F615 PolarHBondContact O-N 2.9Å; S612-V616 WeakPolarHBondContact O-CB 3.41Å; S612-V616 VanDerWaalsContact O-CG2 3.28Å; S612-V616 WeakPolarHBondContact O-CG2 3.44Å; S612-V616 PolarHBondContact O-N 3.16Å
613C98.7Very high98Very high0 Ų034.5 Ų34.50%019%0.188CC..Hα-helixtrans-66.9-40.9179.6-64.80000111.7P192 F585 T609 V610 E611 V616 R617P192-C613 HydrophobicContact CB-CB 4.29Å; P192-C613 WeakPolarHBondContact CB-SG 3.4Å; F585-C613 HydrophobicContact CD1-CB 4.27Å; F585-C613 WeakPolarHBondContact CD1-SG 3.41Å; F585-C613 HydrophobicContact CD2-CB 4.3Å; F585-C613 HydrophobicContact CE1-CB 3.9Å; F585-C613 HydrophobicContact CE2-CB 3.94Å; F585-C613 HydrophobicContact CG-CB 4.47Å; F585-C613 VanDerWaalsContact CG-SG 3.59Å; F585-C613 HydrophobicContact CZ-CB 3.72Å; T609-C613 PolarHBondContact O-N 3.29Å; T609-C613 PolarHBondContact O-SG 2.83Å; V610-C613 PolarHBondContact O-N 3.42Å; E611-C613 VanDerWaalsContact C-N 3.35Å; C613-V616 PolarHBondContact O-N 2.98Å; C613-R617 WeakPolarHBondContact O-CB 3.47Å; C613-R617 WeakPolarHBondContact O-CG 3.3Å; C613-R617 PolarHBondContact O-N 2.9Å
614N98.6Very high97.9Very high67 Ų6737.1 Ų37.136%0.35820%0.201SC..Hα-helixtrans-64.3-42.9176.4-68.7-9.7000111V610 E611 A618 L632V610-N614 WeakPolarHBondContact O-CB 3.49Å; V610-N614 PolarHBondContact O-N 3.36Å; V610-N614 PolarHBondContact O-ND2 3.39Å; V610-N614 PolarHBondContact O-OD1 2.95Å; E611-N614 PolarHBondContact O-N 3.13Å; N614-A618 WeakPolarHBondContact O-CB 3.4Å; N614-A618 PolarHBondContact O-N 3.38Å; N614-L632 HydrophobicContact CB-CD2 4.31Å
615F98.8Very high97.7Very high0 Ų041.1 Ų41.10%022%0.222CC..Hα-helixtrans-59.6-48173.4161.5-110.2000112.1L572 E611 S612 A618 M619 L632 L633 A636 I758L572-F615 HydrophobicContact CB-CE1 4.17Å; L572-F615 HydrophobicContact CD2-CD1 4.47Å; E611-F615 WeakPolarHBondContact O-CB 3.42Å; E611-F615 PolarHBondContact O-N 3.01Å; S612-F615 PolarHBondContact O-N 2.9Å; F615-A618 PolarHBondContact O-N 2.86Å; F615-M619 HydrophobicContact CD2-CG 4.04Å; F615-M619 HydrophobicContact CE1-CG 4.35Å; F615-M619 HydrophobicContact CE2-CG 3.35Å; F615-M619 HydrophobicContact CE2-SD 3.97Å; F615-M619 HydrophobicContact CZ-CG 3.53Å; F615-M619 HydrophobicContact CZ-SD 4.31Å; F615-M619 PolarHBondContact O-N 2.99Å; F615-L632 HydrophobicContact CB-CB 4.04Å; F615-L632 HydrophobicContact CD2-CB 4.45Å; F615-L633 HydrophobicContact CD1-CD1 4.47Å; F615-L633 HydrophobicContact CD2-CB 3.7Å; F615-L633 HydrophobicContact CD2-CD1 4.27Å; F615-L633 HydrophobicContact CE1-CD1 3.99Å; F615-L633 HydrophobicContact CE2-CB 3.63Å; F615-L633 HydrophobicContact CE2-CD1 3.77Å; F615-L633 HydrophobicContact CE2-CG 4.19Å; F615-L633 HydrophobicContact CG-CB 4.49Å; F615-L633 HydrophobicContact CZ-CB 4.38Å; F615-L633 HydrophobicContact CZ-CD1 3.61Å; F615-L633 HydrophobicContact CZ-CG 4.49Å; F615-A636 HydrophobicContact CB-CB 4.11Å; F615-I758 HydrophobicContact CE1-CD1 4.04Å; F615-I758 HydrophobicContact CZ-CD1 3.83Å; F615-I758 HydrophobicContact CZ-CG1 3.9Å
616V98.8Very high97.5Very high0 Ų044.3 Ų44.30%024%0.239CC..Hα-helixtrans-62.6-45.5180167.90000111.6Q575 L576 Y579 F585 S612 C613 A618 M619 E620Q575-V616 HydrophobicContact CB-CG2 3.99Å; L576-V616 HydrophobicContact CB-CG2 4.13Å; L576-V616 HydrophobicContact CD1-CG1 4.03Å; L576-V616 HydrophobicContact CD1-CG2 4.47Å; Y579-V616 VanDerWaalsContact CB-CG1 3.45Å; Y579-V616 HydrophobicContact CD1-CG1 3.55Å; Y579-V616 HydrophobicContact CD2-CG1 4.33Å; Y579-V616 HydrophobicContact CE1-CG1 4.39Å; Y579-V616 HydrophobicContact CG-CG1 3.5Å; F585-V616 HydrophobicContact CE1-CB 3.93Å; F585-V616 HydrophobicContact CE1-CG1 3.8Å; F585-V616 HydrophobicContact CE1-CG2 4.45Å; F585-V616 HydrophobicContact CZ-CB 4.14Å; F585-V616 HydrophobicContact CZ-CG1 3.96Å; S612-V616 WeakPolarHBondContact O-CB 3.41Å; S612-V616 VanDerWaalsContact O-CG2 3.28Å; S612-V616 WeakPolarHBondContact O-CG2 3.44Å; S612-V616 PolarHBondContact O-N 3.16Å; C613-V616 PolarHBondContact O-N 2.98Å; V616-A618 VanDerWaalsContact C-N 3.33Å; V616-A618 PolarHBondContact O-N 3.06Å; V616-M619 WeakPolarHBondContact O-CB 3.49Å; V616-M619 PolarHBondContact O-N 3.38Å; V616-M619 VanDerWaalsContact O-N 3.16Å; V616-E620 PolarHBondContact O-N 2.79Å; V616-E620 VanDerWaalsContact O-N 3.15Å
617R98.5Very high97.4Very high117 Ų11751.6 Ų51.644%0.44227%0.273SS..Hα-helixtrans-58.6-45175.5-73.8177.1-177.9125.40.9111.7F585 C613 M619 E620 D621F585-R617 HydrophobicContact CE2-CG 4.29Å; F585-R617 HydrophobicContact CZ-CG 4.15Å; C613-R617 WeakPolarHBondContact O-CB 3.47Å; C613-R617 WeakPolarHBondContact O-CG 3.3Å; C613-R617 PolarHBondContact O-N 2.9Å; R617-M619 VanDerWaalsContact C-N 3.3Å; R617-M619 PolarHBondContact O-N 2.96Å; R617-E620 PolarHBondContact O-N 3.39Å; R617-D621 PolarHBondContact O-N 2.8Å
618A98.4Very high97.4Very high4 Ų453.5 Ų53.53%0.03328%0.283CS..Hα-helixtrans-65.7-33177.800000112.8N614 F615 V616 E620 D621 E624 K629 L632N614-A618 WeakPolarHBondContact O-CB 3.4Å; N614-A618 PolarHBondContact O-N 3.38Å; F615-A618 PolarHBondContact O-N 2.86Å; V616-A618 VanDerWaalsContact C-N 3.33Å; V616-A618 PolarHBondContact O-N 3.06Å; A618-E620 VanDerWaalsContact C-N 3.32Å; A618-D621 PolarHBondContact O-N 3.47Å; A618-E624 HydrophobicContact CB-CG 4.22Å; A618-K629 HydrophobicContact CB-CG 4.26Å; A618-K629 WeakPolarHBondContact O-CD 3.17Å; A618-K629 WeakPolarHBondContact O-CE 3.46Å; A618-K629 PolarHBondContact O-NZ 3.48Å; A618-L632 HydrophobicContact CB-CD1 3.39Å
619M98.2Very high97.4Very high19 Ų1954.3 Ų54.39%0.09429%0.287CS..Hα-helixtrans-61.8-41.9173.4-82.1-63.4-68.600112.1L576 F615 V616 R617 K629 D757 I758 L761L576-M619 HydrophobicContact CD1-CB 3.81Å; L576-M619 HydrophobicContact CD1-CG 4.49Å; L576-M619 HydrophobicContact CD2-CB 4.28Å; L576-M619 HydrophobicContact CD2-CE 3.93Å; L576-M619 HydrophobicContact CD2-CG 4.23Å; F615-M619 HydrophobicContact CD2-CG 4.04Å; F615-M619 HydrophobicContact CE1-CG 4.35Å; F615-M619 HydrophobicContact CE2-CG 3.35Å; F615-M619 HydrophobicContact CE2-SD 3.97Å; F615-M619 HydrophobicContact CZ-CG 3.53Å; F615-M619 HydrophobicContact CZ-SD 4.31Å; F615-M619 PolarHBondContact O-N 2.99Å; V616-M619 WeakPolarHBondContact O-CB 3.49Å; V616-M619 PolarHBondContact O-N 3.38Å; V616-M619 VanDerWaalsContact O-N 3.16Å; R617-M619 VanDerWaalsContact C-N 3.3Å; R617-M619 PolarHBondContact O-N 2.96Å; M619-K629 PolarHBondContact O-NZ 2.93Å; M619-K629 VanDerWaalsContact O-NZ 3.15Å; M619-K629 HydrophobicContact SD-CB 4.33Å; M619-K629 HydrophobicContact SD-CD 4.02Å; M619-K629 HydrophobicContact SD-CG 4.43Å; M619-D757 HydrophobicContact CE-CB 3.95Å; M619-I758 HydrophobicContact CE-CG1 4.46Å; M619-L761 HydrophobicContact SD-CD1 3.71Å; M619-L761 HydrophobicContact SD-CD2 4.18Å; M619-L761 HydrophobicContact SD-CG 4.24Å
620E97.5Very high97.3Very high79 Ų7954.5 Ų54.537%0.36929%0.287SS..Hα-helixtrans-82.8-14.2-178.6-62.4-56.5106.200114.2L576 Y579 R580 V616 R617 A618 P622L576-E620 HydrophobicContact CD1-CG 4.22Å; Y579-E620 HydrophobicContact CD1-CG 4.07Å; Y579-E620 HydrophobicContact CE1-CG 4.21Å; R580-E620 IonicContact CZ-OE1 3.67Å; R580-E620 IonicContact NE-OE1 3.72Å; R580-E620 PolarHBondContact NE-OE1 2.76Å; R580-E620 IonicContact NE-OE2 3.06Å; R580-E620 IonicContact NH2-OE1 3.57Å; R580-E620 PolarHBondContact NH2-OE1 3.35Å; V616-E620 PolarHBondContact O-N 2.79Å; V616-E620 VanDerWaalsContact O-N 3.15Å; R617-E620 PolarHBondContact O-N 3.39Å; A618-E620 VanDerWaalsContact C-N 3.32Å; E620-P622 WeakPolarHBondContact O-CD 3.36Å
621D97.1Very high97.3Very high59 Ų5958 Ų5832%0.31630%0.298SS..  trans-80118.2174.9-168.6-24.7000110.9R617 A618 S623 E624 K629R617-D621 PolarHBondContact O-N 2.8Å; A618-D621 PolarHBondContact O-N 3.47Å; D621-S623 VanDerWaalsContact C-N 3.27Å; D621-S623 VanDerWaalsContact CG-OG 3.28Å; D621-S623 PolarHBondContact O-N 3.15Å; D621-S623 WeakPolarHBondContact OD1-CA 3.37Å; D621-S623 WeakPolarHBondContact OD1-CB 3.48Å; D621-S623 PolarHBondContact OD1-N 3.21Å; D621-S623 PolarHBondContact OD1-OG 3.47Å; D621-S623 PolarHBondContact OD2-OG 3.17Å; D621-E624 HydrophobicContact CB-CB 4.09Å; D621-E624 HydrophobicContact CB-CG 3.65Å; D621-E624 PolarHBondContact O-N 2.86Å; D621-K629 PolarHBondContact O-NZ 3.15Å
622P94.1Very high97.2Very high127 Ų12756.8 Ų56.883%0.82529%0.293SS*.THydrogen-bonded Turntrans-72.9-17.6177.930.5-35.5000113.7E620E620-P622 WeakPolarHBondContact O-CD 3.36Å
623S96Very high97.2Very high103 Ų10356.8 Ų56.872%0.7229%0.293SS*.THydrogen-bonded Turntrans-83.5-18.4178740000113.3D621D621-S623 VanDerWaalsContact C-N 3.27Å; D621-S623 VanDerWaalsContact CG-OG 3.28Å; D621-S623 PolarHBondContact O-N 3.15Å; D621-S623 WeakPolarHBondContact OD1-CA 3.37Å; D621-S623 WeakPolarHBondContact OD1-CB 3.48Å; D621-S623 PolarHBondContact OD1-N 3.21Å; D621-S623 PolarHBondContact OD1-OG 3.47Å; D621-S623 PolarHBondContact OD2-OG 3.17Å
624E95.9Very high97.2Very high63 Ų6363.4 Ų63.429%0.29432%0.318SS..SBendtrans-73.5134.7178.9-78.3-72.5-178.300111.9A618 D621 N628 K629A618-E624 HydrophobicContact CB-CG 4.22Å; D621-E624 HydrophobicContact CB-CB 4.09Å; D621-E624 HydrophobicContact CB-CG 3.65Å; D621-E624 PolarHBondContact O-N 2.86Å; E624-N628 PolarHBondContact OE2-ND2 3.02Å; E624-K629 HydrophobicContact CB-CG 4.4Å; E624-K629 WeakPolarHBondContact O-CE 3.45Å
625D94.1Very high97.2Very high90 Ų9064.7 Ų64.748%0.48132%0.324SS..  trans-79.7157.9178.174.862.2000112.3E627 N628 K629D625-E627 VanDerWaalsContact C-N 3.26Å; D625-E627 PolarHBondContact O-N 2.89Å; D625-E627 VanDerWaalsContact OD1-CA 3.3Å; D625-E627 WeakPolarHBondContact OD1-CA 3.47Å; D625-E627 VanDerWaalsContact OD1-CB 3.26Å; D625-E627 WeakPolarHBondContact OD1-CB 3.45Å; D625-E627 PolarHBondContact OD1-N 2.87Å; D625-N628 PolarHBondContact O-N 3.21Å; D625-N628 PolarHBondContact OD1-N 3.31Å; D625-K629 WeakPolarHBondContact O-CG 3.45Å; D625-K629 PolarHBondContact O-N 3.4Å; D625-K629 VanDerWaalsContact O-N 3.09Å
626N94.7Very high97.2Very high69 Ų6964.7 Ų64.737%0.36933%0.325SS..Hα-helixtrans-67.2-25.8-177.6-69.9-33.9000113.3L630 L761N626-L630 VanDerWaalsContact O-CB 3.22Å; N626-L630 WeakPolarHBondContact O-CB 3.46Å; N626-L630 PolarHBondContact O-N 2.81Å; N626-L761 HydrophobicContact CB-CD2 4.42Å
627E95.5Very high97.2Very high161 Ų16165.1 Ų65.175%0.75233%0.328SS*.Hα-helixtrans-70-44.4179.4-173179171.600110.2D625 L630 K631D625-E627 VanDerWaalsContact C-N 3.26Å; D625-E627 PolarHBondContact O-N 2.89Å; D625-E627 VanDerWaalsContact OD1-CA 3.3Å; D625-E627 WeakPolarHBondContact OD1-CA 3.47Å; D625-E627 VanDerWaalsContact OD1-CB 3.26Å; D625-E627 WeakPolarHBondContact OD1-CB 3.45Å; D625-E627 PolarHBondContact OD1-N 2.87Å; E627-L630 PolarHBondContact O-N 3.22Å; E627-K631 WeakPolarHBondContact O-CB 3.48Å; E627-K631 PolarHBondContact O-N 3.15Å
628N96.9Very high97.1Very high44 Ų4462.2 Ų62.224%0.23533%0.329CS..Hα-helixtrans-66.5-43.6175.2-167.244.2000111.6E624 D625 L630 K631 L632E624-N628 PolarHBondContact OE2-ND2 3.02Å; D625-N628 PolarHBondContact O-N 3.21Å; D625-N628 PolarHBondContact OD1-N 3.31Å; N628-L630 VanDerWaalsContact C-N 3.28Å; N628-L630 PolarHBondContact O-N 2.69Å; N628-K631 WeakPolarHBondContact O-CB 3.48Å; N628-K631 PolarHBondContact O-N 3.24Å; N628-K631 VanDerWaalsContact O-N 3.16Å; N628-L632 WeakPolarHBondContact O-CG 3.31Å; N628-L632 PolarHBondContact O-N 3.01Å
629K98.2Very high97.1Very high20 Ų2064 Ų649%0.08734%0.336CS..Hα-helixtrans-54.9-45.1172.7-68.4178.2-162.8-1400111.5A618 M619 D621 E624 D625 L632 L633 L761A618-K629 HydrophobicContact CB-CG 4.26Å; A618-K629 WeakPolarHBondContact O-CD 3.17Å; A618-K629 WeakPolarHBondContact O-CE 3.46Å; A618-K629 PolarHBondContact O-NZ 3.48Å; M619-K629 PolarHBondContact O-NZ 2.93Å; M619-K629 VanDerWaalsContact O-NZ 3.15Å; M619-K629 HydrophobicContact SD-CB 4.33Å; M619-K629 HydrophobicContact SD-CD 4.02Å; M619-K629 HydrophobicContact SD-CG 4.43Å; D621-K629 PolarHBondContact O-NZ 3.15Å; E624-K629 HydrophobicContact CB-CG 4.4Å; E624-K629 WeakPolarHBondContact O-CE 3.45Å; D625-K629 WeakPolarHBondContact O-CG 3.45Å; D625-K629 PolarHBondContact O-N 3.4Å; D625-K629 VanDerWaalsContact O-N 3.09Å; K629-L632 PolarHBondContact O-N 2.68Å; K629-L633 WeakPolarHBondContact O-CB 3.35Å; K629-L633 PolarHBondContact O-N 3.03Å; K629-L761 HydrophobicContact CB-CD1 4.12Å; K629-L761 HydrophobicContact CB-CD2 4.06Å; K629-L761 HydrophobicContact CD-CD2 4.21Å
630L97.3Very high97.1Very high12 Ų1263.2 Ų63.26%0.06333%0.332CS..Hα-helixtrans-67.7-38.4178.6-18060.4000112.8N626 E627 N628 L633 R634 F762N626-L630 VanDerWaalsContact O-CB 3.22Å; N626-L630 WeakPolarHBondContact O-CB 3.46Å; N626-L630 PolarHBondContact O-N 2.81Å; E627-L630 PolarHBondContact O-N 3.22Å; N628-L630 VanDerWaalsContact C-N 3.28Å; N628-L630 PolarHBondContact O-N 2.69Å; L630-L633 HydrophobicContact CD1-CD2 4.28Å; L630-R634 WeakPolarHBondContact O-CG 3.46Å; L630-R634 PolarHBondContact O-N 3.2Å; L630-R634 VanDerWaalsContact O-N 3.11Å; L630-F762 HydrophobicContact CD1-CD1 3.77Å; L630-F762 HydrophobicContact CD1-CE1 3.22Å; L630-F762 HydrophobicContact CD1-CE2 4.2Å; L630-F762 HydrophobicContact CD1-CG 4.47Å; L630-F762 HydrophobicContact CD1-CZ 3.48Å; L630-F762 VanDerWaalsContact CD1-CZ 3.48Å
631K97.8Very high97Very high126 Ų12662 Ų6255%0.54833%0.327SS..Hα-helixtrans-61.2-47.9173.7178.2-174.2174.4-173.20111E627 N628 R634 L635E627-K631 WeakPolarHBondContact O-CB 3.48Å; E627-K631 PolarHBondContact O-N 3.15Å; N628-K631 WeakPolarHBondContact O-CB 3.48Å; N628-K631 PolarHBondContact O-N 3.24Å; N628-K631 VanDerWaalsContact O-N 3.16Å; K631-R634 PolarHBondContact O-N 3.46Å; K631-L635 HydrophobicContact CG-CD1 4.48Å; K631-L635 WeakPolarHBondContact O-CG 3.25Å; K631-L635 PolarHBondContact O-N 2.84Å; K631-L635 VanDerWaalsContact O-N 3.09Å
632L98.6Very high97Very high32 Ų3262.1 Ų62.117%0.16833%0.327CS..Hα-helixtrans-65-40.3178.8-68.9171.3000111.9N614 F615 A618 N628 K629 R634 L635 A636N614-L632 HydrophobicContact CB-CD2 4.31Å; F615-L632 HydrophobicContact CB-CB 4.04Å; F615-L632 HydrophobicContact CD2-CB 4.45Å; A618-L632 HydrophobicContact CB-CD1 3.39Å; N628-L632 WeakPolarHBondContact O-CG 3.31Å; N628-L632 PolarHBondContact O-N 3.01Å; K629-L632 PolarHBondContact O-N 2.68Å; L632-R634 VanDerWaalsContact C-N 3.32Å; L632-R634 PolarHBondContact O-N 2.84Å; L632-L635 HydrophobicContact CD2-CD1 4.49Å; L632-L635 PolarHBondContact O-N 3Å; L632-A636 WeakPolarHBondContact O-CB 3.29Å; L632-A636 PolarHBondContact O-N 3.04Å
633L98.4Very high97.2Very high0 Ų057.6 Ų57.60%030%0.296CS..Hα-helixtrans-55.4-46.7172.8176.165.9000111.8L572 F615 K629 L630 A636 A637 I758 L761 F762L572-L633 HydrophobicContact CD1-CD1 3.76Å; F615-L633 HydrophobicContact CD1-CD1 4.47Å; F615-L633 HydrophobicContact CD2-CB 3.7Å; F615-L633 HydrophobicContact CD2-CD1 4.27Å; F615-L633 HydrophobicContact CE1-CD1 3.99Å; F615-L633 HydrophobicContact CE2-CB 3.63Å; F615-L633 HydrophobicContact CE2-CD1 3.77Å; F615-L633 HydrophobicContact CE2-CG 4.19Å; F615-L633 HydrophobicContact CG-CB 4.49Å; F615-L633 HydrophobicContact CZ-CB 4.38Å; F615-L633 HydrophobicContact CZ-CD1 3.61Å; F615-L633 HydrophobicContact CZ-CG 4.49Å; K629-L633 WeakPolarHBondContact O-CB 3.35Å; K629-L633 PolarHBondContact O-N 3.03Å; L630-L633 HydrophobicContact CD1-CD2 4.28Å; L633-A636 PolarHBondContact O-N 2.81Å; L633-A637 VanDerWaalsContact O-CB 3.32Å; L633-A637 WeakPolarHBondContact O-CB 3.39Å; L633-A637 PolarHBondContact O-N 3.38Å; L633-I758 HydrophobicContact CD1-CG2 3.93Å; L633-I758 HydrophobicContact CD2-CG2 3.71Å; L633-L761 HydrophobicContact CD2-CD1 4.37Å; L633-F762 HydrophobicContact CD2-CE2 3.47Å; L633-F762 VanDerWaalsContact CD2-CE2 3.47Å; L633-F762 HydrophobicContact CD2-CZ 3.43Å; L633-F762 VanDerWaalsContact CD2-CZ 3.43Å
634R97.8Very high97.2Very high139 Ų13954.7 Ų54.753%0.52527%0.269SS..Hα-helixtrans-64.1-40.8179.2-73.1173.4178.7148.20.7112.2L630 K631 L632 A638L630-R634 WeakPolarHBondContact O-CG 3.46Å; L630-R634 PolarHBondContact O-N 3.2Å; L630-R634 VanDerWaalsContact O-N 3.11Å; K631-R634 PolarHBondContact O-N 3.46Å; L632-R634 VanDerWaalsContact C-N 3.32Å; L632-R634 PolarHBondContact O-N 2.84Å; R634-A638 VanDerWaalsContact O-CB 3.32Å; R634-A638 WeakPolarHBondContact O-CB 3.42Å; R634-A638 PolarHBondContact O-N 2.83Å
635L98.4Very high97.2Very high94 Ų9454.6 Ų54.649%0.49227%0.266SS..Hα-helixtrans-64.3-46.2176.1-69.5171.9000111.4K631 L632 A637 A638 K639K631-L635 HydrophobicContact CG-CD1 4.48Å; K631-L635 WeakPolarHBondContact O-CG 3.25Å; K631-L635 PolarHBondContact O-N 2.84Å; K631-L635 VanDerWaalsContact O-N 3.09Å; L632-L635 HydrophobicContact CD2-CD1 4.49Å; L632-L635 PolarHBondContact O-N 3Å; L635-A637 PolarHBondContact O-N 3.47Å; L635-A638 PolarHBondContact O-N 3.05Å; L635-K639 WeakPolarHBondContact O-CB 3.15Å; L635-K639 PolarHBondContact O-N 3.29Å
636A98.7Very high97.4Very high1 Ų152.1 Ų52.11%0.00825%0.253CS..Hα-helixtrans-61.8-43.7177.300000111.7L572 E611 F615 L632 L633 A638 K639 H640L572-A636 HydrophobicContact CD1-CB 3.93Å; L572-A636 HydrophobicContact CD2-CB 3.62Å; L572-A636 HydrophobicContact CG-CB 4.46Å; E611-A636 HydrophobicContact CB-CB 4.2Å; F615-A636 HydrophobicContact CB-CB 4.11Å; L632-A636 WeakPolarHBondContact O-CB 3.29Å; L632-A636 PolarHBondContact O-N 3.04Å; L633-A636 PolarHBondContact O-N 2.81Å; A636-A638 PolarHBondContact O-N 3.06Å; A636-K639 PolarHBondContact O-N 2.87Å; A636-H640 WeakPolarHBondContact O-CB 3.43Å; A636-H640 PolarHBondContact O-N 2.91Å
637A98.3Very high97.5Very high9 Ų948.9 Ų48.97%0.07424%0.236CC..Hα-helixtrans-65-40.7177.900000112.2T564 A568 L572 L633 L635 H640 Q641T564-A637 HydrophobicContact CG2-CB 3.88Å; A568-A637 HydrophobicContact CB-CB 4.34Å; L572-A637 HydrophobicContact CD1-CB 3.84Å; L633-A637 VanDerWaalsContact O-CB 3.32Å; L633-A637 WeakPolarHBondContact O-CB 3.39Å; L633-A637 PolarHBondContact O-N 3.38Å; L635-A637 PolarHBondContact O-N 3.47Å; A637-H640 PolarHBondContact O-N 3.4Å; A637-Q641 WeakPolarHBondContact O-CG 3.5Å; A637-Q641 PolarHBondContact O-N 3.47Å
638A97.1Very high97.5Very high56 Ų5641.8 Ų41.846%0.46320%0.202SC..Hα-helixtrans-65.3-41.7176.200000111.9R634 L635 A636 Q641 L642R634-A638 VanDerWaalsContact O-CB 3.32Å; R634-A638 WeakPolarHBondContact O-CB 3.42Å; R634-A638 PolarHBondContact O-N 2.83Å; L635-A638 PolarHBondContact O-N 3.05Å; A636-A638 PolarHBondContact O-N 3.06Å; A638-Q641 PolarHBondContact O-N 3.17Å; A638-L642 WeakPolarHBondContact O-CB 3.41Å; A638-L642 PolarHBondContact O-N 3.49Å
639K98.1Very high97.4Very high40 Ų4040.4 Ų40.417%0.17420%0.196CC..Hα-helixtrans-61.2-49.2174.2179.370168.6-162.80111.1E188 T609 E611 L635 A636 Q641 L642 L643E188-K639 IonicContact OE2-NZ 3.35Å; T609-K639 HydrophobicContact CG2-CG 4.12Å; E611-K639 HydrophobicContact CB-CB 4.26Å; E611-K639 HydrophobicContact CG-CB 4.13Å; E611-K639 HydrophobicContact CG-CG 4.3Å; E611-K639 WeakPolarHBondContact OE1-CD 3.18Å; E611-K639 WeakPolarHBondContact OE1-CE 3.43Å; E611-K639 IonicContact OE1-NZ 2.71Å; E611-K639 WeakPolarHBondContact OE2-CG 3.32Å; L635-K639 WeakPolarHBondContact O-CB 3.15Å; L635-K639 PolarHBondContact O-N 3.29Å; A636-K639 PolarHBondContact O-N 2.87Å; K639-Q641 VanDerWaalsContact C-N 3.35Å; K639-Q641 PolarHBondContact O-N 2.74Å; K639-L642 WeakPolarHBondContact O-CA 3.39Å; K639-L642 WeakPolarHBondContact O-CB 3.48Å; K639-L642 PolarHBondContact O-N 3.34Å; K639-L642 VanDerWaalsContact O-N 3.07Å; K639-L643 HydrophobicContact CG-CD1 4.45Å; K639-L643 WeakPolarHBondContact O-CG 3.43Å; K639-L643 PolarHBondContact O-N 3.48Å
640H98.3Very high97.4Very high4 Ų439.8 Ų39.82%0.01920%0.195CC..Hα-helixtrans-58.4-46.8179.6-178.787.8000111.4D567 A568 Q571 E590 S607 A636 A637 L642 L643 Y644D567-H640 IonicContact OD2-NE2 2.86Å; A568-H640 HydrophobicContact CB-CB 4.42Å; Q571-H640 VanDerWaalsContact CG-CE1 3.47Å; Q571-H640 WeakPolarHBondContact CG-CE1 3.36Å; E590-H640 IonicContact OE1-NE2 3.44Å; E590-H640 IonicContact OE2-CE1 2.77Å; E590-H640 PolarHBondContact OE2-CE1 3.08Å; E590-H640 IonicContact OE2-NE2 3.5Å; E590-H640 PolarHBondContact OE2-NE2 3.35Å; S607-H640 PolarHBondContact OG-CE1 3.45Å; A636-H640 WeakPolarHBondContact O-CB 3.43Å; A636-H640 PolarHBondContact O-N 2.91Å; A637-H640 PolarHBondContact O-N 3.4Å; H640-L642 VanDerWaalsContact C-N 3.31Å; H640-L642 PolarHBondContact O-N 2.92Å; H640-L643 WeakPolarHBondContact O-CB 3.31Å; H640-L643 PolarHBondContact O-N 3.09Å; H640-L643 VanDerWaalsContact O-N 3.12Å; H640-Y644 PolarHBondContact O-N 3.3Å
641Q96.6Very high97.3Very high54 Ų5440.3 Ų40.325%0.25220%0.201SC..Hα-helixtrans-63.5-33.1174.6-73.4-68.9-61.500113.4S565 A568 A637 A638 K639 R645S565-Q641 VanDerWaalsContact CB-CD 3.45Å; S565-Q641 PolarHBondContact OG-NE2 2.94Å; A568-Q641 HydrophobicContact CB-CG 4.08Å; A637-Q641 WeakPolarHBondContact O-CG 3.5Å; A637-Q641 PolarHBondContact O-N 3.47Å; A638-Q641 PolarHBondContact O-N 3.17Å; K639-Q641 VanDerWaalsContact C-N 3.35Å; K639-Q641 PolarHBondContact O-N 2.74Å; Q641-R645 VanDerWaalsContact O-CG 3.24Å; Q641-R645 WeakPolarHBondContact O-CG 3.46Å; Q641-R645 PolarHBondContact O-N 2.81Å; Q641-R645 VanDerWaalsContact O-N 3.15Å; Q641-R645 PolarHBondContact O-NE 3.18Å
642L96.8Very high97.2Very high61 Ų6134.6 Ų34.632%0.31918%0.177SC..Hα-helixtrans-63.8-46.1171.1175.363.6000111.2F137 A638 K639 H640 Y644 R645 L646F137-L642 HydrophobicContact CD1-CD1 4.41Å; F137-L642 HydrophobicContact CE1-CD1 4.07Å; A638-L642 WeakPolarHBondContact O-CB 3.41Å; A638-L642 PolarHBondContact O-N 3.49Å; K639-L642 WeakPolarHBondContact O-CA 3.39Å; K639-L642 WeakPolarHBondContact O-CB 3.48Å; K639-L642 PolarHBondContact O-N 3.34Å; K639-L642 VanDerWaalsContact O-N 3.07Å; H640-L642 VanDerWaalsContact C-N 3.31Å; H640-L642 PolarHBondContact O-N 2.92Å; L642-Y644 VanDerWaalsContact C-N 3.35Å; L642-Y644 PolarHBondContact O-N 3.17Å; L642-R645 PolarHBondContact O-N 3.41Å; L642-L646 HydrophobicContact CD1-CD1 4.3Å; L642-L646 HydrophobicContact CD1-CG 4.29Å; L642-L646 HydrophobicContact CG-CD1 4.1Å; L642-L646 WeakPolarHBondContact O-CG 3.34Å; L642-L646 PolarHBondContact O-N 3.41Å
643L97.8Very high97.1Very high31 Ų3133.7 Ų33.716%0.16217%0.173CC..Hα-helixtrans-61.3-43.2178.1-65.9-179.5000111.7V605 T609 K639 H640 R645 L646 A647V605-L643 HydrophobicContact CG1-CB 4Å; T609-L643 HydrophobicContact CG2-CD1 3.5Å; K639-L643 HydrophobicContact CG-CD1 4.45Å; K639-L643 WeakPolarHBondContact O-CG 3.43Å; K639-L643 PolarHBondContact O-N 3.48Å; H640-L643 WeakPolarHBondContact O-CB 3.31Å; H640-L643 PolarHBondContact O-N 3.09Å; H640-L643 VanDerWaalsContact O-N 3.12Å; L643-R645 VanDerWaalsContact C-N 3.35Å; L643-R645 PolarHBondContact O-N 2.83Å; L643-L646 HydrophobicContact CD2-CD1 4.49Å; L643-L646 PolarHBondContact O-N 3.49Å; L643-A647 WeakPolarHBondContact O-CB 3.49Å; L643-A647 PolarHBondContact O-N 3.47Å
644Y96.1Very high97.1Very high43 Ų4334.2 Ų34.217%0.16918%0.176CC..Hα-helixtrans-59.7-43.8176.2-158.3-83.8000112.1V605 H640 L642 L646 A647 M648V605-Y644 HydrophobicContact CG2-CD2 3.83Å; V605-Y644 HydrophobicContact CG2-CG 4.3Å; H640-Y644 PolarHBondContact O-N 3.3Å; L642-Y644 VanDerWaalsContact C-N 3.35Å; L642-Y644 PolarHBondContact O-N 3.17Å; Y644-L646 PolarHBondContact O-N 3.48Å; Y644-A647 PolarHBondContact O-N 3.32Å; Y644-M648 HydrophobicContact CD1-CG 3.92Å; Y644-M648 HydrophobicContact CD1-SD 3.69Å; Y644-M648 HydrophobicContact CE1-CG 3.81Å; Y644-M648 HydrophobicContact CE1-SD 3.42Å; Y644-M648 WeakPolarHBondContact CE1-SD 3.48Å; Y644-M648 WeakPolarHBondContact O-CG 3.15Å; Y644-M648 PolarHBondContact O-N 3.48Å
645R96.1Very high97.1Very high61 Ų6128 Ų2823%0.2315%0.152CC..Hα-helixtrans-64.4-38.6175.1-70.2177.4-76.2171.90.8112.8M136 F137 Q641 L642 L643 T649M136-R645 HydrophobicContact CE-CB 4.45Å; M136-R645 HydrophobicContact CE-CG 4.04Å; M136-R645 WeakPolarHBondContact O-CD 3.28Å; F137-R645 HydrophobicContact CE1-CB 3.96Å; F137-R645 HydrophobicContact CZ-CB 4.25Å; Q641-R645 VanDerWaalsContact O-CG 3.24Å; Q641-R645 WeakPolarHBondContact O-CG 3.46Å; Q641-R645 PolarHBondContact O-N 2.81Å; Q641-R645 VanDerWaalsContact O-N 3.15Å; Q641-R645 PolarHBondContact O-NE 3.18Å; L642-R645 PolarHBondContact O-N 3.41Å; L643-R645 VanDerWaalsContact C-N 3.35Å; L643-R645 PolarHBondContact O-N 2.83Å; R645-T649 WeakPolarHBondContact O-CB 3.49Å; R645-T649 VanDerWaalsContact O-CG2 3.29Å; R645-T649 WeakPolarHBondContact O-CG2 3.09Å; R645-T649 PolarHBondContact O-N 2.82Å; R645-T649 VanDerWaalsContact O-N 3.15Å; R645-T649 PolarHBondContact O-OG1 2.94Å
646L97.1Very high97.1Very high38 Ų3823.5 Ų23.520%0.19913%0.129CC..Hα-helixtrans-66.1-43.7175.3-71.1171.7000111.3F137 L642 L643 Y644 T649 G650 A651F137-L646 HydrophobicContact CE1-CD2 4.39Å; F137-L646 HydrophobicContact CZ-CD2 4.28Å; L642-L646 HydrophobicContact CD1-CD1 4.3Å; L642-L646 HydrophobicContact CD1-CG 4.29Å; L642-L646 HydrophobicContact CG-CD1 4.1Å; L642-L646 WeakPolarHBondContact O-CG 3.34Å; L642-L646 PolarHBondContact O-N 3.41Å; L643-L646 HydrophobicContact CD2-CD1 4.49Å; L643-L646 PolarHBondContact O-N 3.49Å; Y644-L646 PolarHBondContact O-N 3.48Å; L646-T649 PolarHBondContact O-N 3.13Å; L646-T649 PolarHBondContact O-OG1 2.8Å; L646-G650 PolarHBondContact O-N 3.44Å; L646-A651 HydrophobicContact CB-CB 4.36Å; L646-A651 HydrophobicContact CD2-CB 4.1Å; L646-A651 CarbonylContact O-C 3.58Å; L646-A651 VanDerWaalsContact O-CA 3.31Å; L646-A651 WeakPolarHBondContact O-CA 3.42Å; L646-A651 WeakPolarHBondContact O-CB 3.38Å; L646-A651 PolarHBondContact O-N 3.32Å
647A97.1Very high97.1Very high1 Ų123.5 Ų23.51%0.00813%0.128CC..Hα-helixtrans-60.7-51.2176.700000111.3E603 V605 L643 Y644 T649 G650E603-A647 HydrophobicContact CB-CB 4.11Å; E603-A647 HydrophobicContact CG-CB 3.77Å; V605-A647 HydrophobicContact CG2-CB 3.75Å; L643-A647 WeakPolarHBondContact O-CB 3.49Å; L643-A647 PolarHBondContact O-N 3.47Å; Y644-A647 PolarHBondContact O-N 3.32Å; A647-T649 PolarHBondContact O-N 3.37Å; A647-G650 PolarHBondContact O-N 3.12Å; A647-G650 VanDerWaalsContact O-N 3.07Å
648M95.7Very high97Very high11 Ų1124 Ų245%0.05413%0.129CC..Hα-helixtrans-58.2-34.5178.8-75.1-169.669.400113.5M136 L296 S592 M593 L596 F597 Y644 G650M136-M648 HydrophobicContact CE-CB 4.03Å; M136-M648 HydrophobicContact CE-CE 3.94Å; M136-M648 HydrophobicContact CE-CG 4.36Å; M136-M648 HydrophobicContact CE-SD 3.47Å; M136-M648 WeakPolarHBondContact CE-SD 3.2Å; L296-M648 HydrophobicContact CD1-CE 4.32Å; S592-M648 WeakPolarHBondContact OG-CG 3.48Å; M593-M648 HydrophobicContact CE-CE 3.51Å; M593-M648 HydrophobicContact CG-CE 4.27Å; L596-M648 HydrophobicContact CD1-CB 4.35Å; L596-M648 HydrophobicContact CD1-CE 4.19Å; F597-M648 WeakPolarHBondContact CE2-O 3.46Å; Y644-M648 HydrophobicContact CD1-CG 3.92Å; Y644-M648 HydrophobicContact CD1-SD 3.69Å; Y644-M648 HydrophobicContact CE1-CG 3.81Å; Y644-M648 HydrophobicContact CE1-SD 3.42Å; Y644-M648 WeakPolarHBondContact CE1-SD 3.48Å; Y644-M648 WeakPolarHBondContact O-CG 3.15Å; Y644-M648 PolarHBondContact O-N 3.48Å; M648-G650 VanDerWaalsContact C-N 3.27Å; M648-G650 PolarHBondContact O-N 3.38Å
649T96.3Very high97Very high16 Ų1621.3 Ų21.310%0.09811%0.107CC..THydrogen-bonded Turntrans-89.914-178.257.30000113.4H133 M136 F137 F597 R645 L646 A647 A651H133-T649 HydrophobicContact CB-CG2 3.57Å; M136-T649 HydrophobicContact CB-CG2 4.41Å; M136-T649 HydrophobicContact CG-CG2 4.17Å; F137-T649 HydrophobicContact CE2-CG2 4.37Å; F597-T649 WeakPolarHBondContact CZ-O 3.31Å; R645-T649 WeakPolarHBondContact O-CB 3.49Å; R645-T649 VanDerWaalsContact O-CG2 3.29Å; R645-T649 WeakPolarHBondContact O-CG2 3.09Å; R645-T649 PolarHBondContact O-N 2.82Å; R645-T649 VanDerWaalsContact O-N 3.15Å; R645-T649 PolarHBondContact O-OG1 2.94Å; L646-T649 PolarHBondContact O-N 3.13Å; L646-T649 PolarHBondContact O-OG1 2.8Å; A647-T649 PolarHBondContact O-N 3.37Å; T649-A651 VanDerWaalsContact C-N 3.3Å; T649-A651 PolarHBondContact O-N 2.98Å
650G96.2Very high96.9Very high6 Ų619.4 Ų19.46%0.06210%0.098CC..THydrogen-bonded Turntrans75.420174.600000113.4P177 L646 A647 M648P177-G650 WeakPolarHBondContact CG-O 3.48Å; L646-G650 PolarHBondContact O-N 3.44Å; A647-G650 PolarHBondContact O-N 3.12Å; A647-G650 VanDerWaalsContact O-N 3.07Å; M648-G650 VanDerWaalsContact C-N 3.27Å; M648-G650 PolarHBondContact O-N 3.38Å
651A96.6Very high96.8Very high24 Ų2422.7 Ų22.720%0.19811%0.111CC..  trans-109.535.1176.800000110.8R185 L646 T649R185-A651 PolarHBondContact NH1-O 2.7Å; R185-A651 PolarHBondContact NH2-O 3.3Å; R185-A651 VanDerWaalsContact NH2-O 3.15Å; L646-A651 HydrophobicContact CB-CB 4.36Å; L646-A651 HydrophobicContact CD2-CB 4.1Å; L646-A651 CarbonylContact O-C 3.58Å; L646-A651 VanDerWaalsContact O-CA 3.31Å; L646-A651 WeakPolarHBondContact O-CA 3.42Å; L646-A651 WeakPolarHBondContact O-CB 3.38Å; L646-A651 PolarHBondContact O-N 3.32Å; T649-A651 VanDerWaalsContact C-N 3.3Å; T649-A651 PolarHBondContact O-N 2.98Å
652G95.3Very high96.6Very high5 Ų520.5 Ų20.55%0.05210%0.101CC..  trans-76.2-171.1172.300000113.6R185 E603R185-G652 PolarHBondContact NH2-O 3Å; E603-G652 WeakPolarHBondContact OE2-CA 3.1Å
653I97.4Very high96.3Very high14 Ų1417.9 Ų17.97%0.0729%0.088CC..SBendtrans-107.4-53.9-178.8-61.1162.2000109.8T182 R185 Y186 H656 L657T182-I653 HydrophobicContact CG2-CG2 4.26Å; R185-I653 HydrophobicContact CB-CD1 3.83Å; R185-I653 HydrophobicContact CB-CG1 3.84Å; Y186-I653 HydrophobicContact CD2-CG2 4.48Å; I653-H656 PolarHBondContact O-N 2.73Å; I653-L657 HydrophobicContact CG2-CD1 3.71Å; I653-L657 HydrophobicContact CG2-CG 4.26Å; I653-L657 PolarHBondContact O-N 2.98Å; I653-L657 VanDerWaalsContact O-N 3.09Å
654D97.8Very high96Very high11 Ų1116.5 Ų16.56%0.0598%0.081CC..Hα-helixtrans-72.8-45.7-157.8-66.9-90.2000113.8E603 T604 R606 H656 L657 F658 W682E603-D654 PolarHBondContact OE1-N 3.39Å; T604-D654 WeakPolarHBondContact CB-OD2 3.31Å; T604-D654 VanDerWaalsContact OG1-CB 3.27Å; T604-D654 WeakPolarHBondContact OG1-CB 3.37Å; R606-D654 IonicContact CZ-OD1 3.38Å; R606-D654 IonicContact CZ-OD2 2.72Å; R606-D654 IonicContact NE-OD1 3.1Å; R606-D654 PolarHBondContact NE-OD1 2.92Å; R606-D654 IonicContact NE-OD2 3.17Å; R606-D654 PolarHBondContact NE-OD2 3.45Å; R606-D654 IonicContact NH2-OD1 3.2Å; R606-D654 PolarHBondContact NH2-OD1 3.34Å; R606-D654 IonicContact NH2-OD2 2.64Å; D654-H656 PolarHBondContact O-N 3.02Å; D654-L657 PolarHBondContact O-N 3.35Å; D654-F658 VanDerWaalsContact O-CB 3.3Å; D654-F658 WeakPolarHBondContact O-CB 3.36Å; D654-F658 PolarHBondContact O-N 3.33Å; D654-W682 WeakPolarHBondContact OD1-CH2 3.45Å; D654-W682 VanDerWaalsContact OD1-CZ2 3.24Å; D654-W682 WeakPolarHBondContact OD1-CZ2 3.48Å
655R97.4Very high95.7Very high7 Ų719.7 Ų19.73%0.02610%0.096CC..Hα-helixtrans-63.8-32.8177-61.8-59.1176.7-80.2-1.6111.9V232 W236 Y589 T602 E603 T604 C659V232-R655 HydrophobicContact CG1-CB 4.04Å; V232-R655 HydrophobicContact CG1-CG 4.16Å; V232-R655 HydrophobicContact CG2-CB 4.25Å; W236-R655 VanDerWaalsContact CE3-CD 3.44Å; W236-R655 VanDerWaalsContact CH2-CZ 3.4Å; Y589-R655 PolarHBondContact OH-NH2 3.23Å; Y589-R655 VanDerWaalsContact OH-NH2 3.07Å; T602-R655 WeakPolarHBondContact O-CG 3.3Å; T602-R655 PolarHBondContact O-NE 2.93Å; T602-R655 PolarHBondContact OG1-NH2 3.3Å; E603-R655 WeakPolarHBondContact OE1-CG 3.45Å; E603-R655 PolarHBondContact OE1-N 3.44Å; E603-R655 IonicContact OE1-NH1 3.69Å; T604-R655 PolarHBondContact OG1-NH1 2.84Å; R655-C659 PolarHBondContact O-N 2.93Å; R655-C659 PolarHBondContact O-SG 2.82Å; R655-C659 VanDerWaalsContact O-SG 3.35Å
656H98.4Very high95.2Very high0 Ų023.3 Ų23.30%011%0.11CC..Hα-helixtrans-68.5-49.1177.2-173.3-156.3000111.8P177 T182 Q218 L221 I653 D654 F658 C659 L660P177-H656 HydrophobicContact CG-CB 4.24Å; P177-H656 PolarHBondContact O-CE1 3.27Å; T182-H656 HydrophobicContact CG2-CB 4.23Å; T182-H656 PolarHBondContact OG1-ND1 3.49Å; Q218-H656 PolarHBondContact OE1-CE1 3.23Å; Q218-H656 PolarHBondContact OE1-NE2 3.18Å; L221-H656 VanDerWaalsContact CD2-CD2 3.48Å; L221-H656 WeakPolarHBondContact CD2-CD2 3.48Å; I653-H656 PolarHBondContact O-N 2.73Å; D654-H656 PolarHBondContact O-N 3.02Å; H656-F658 VanDerWaalsContact C-N 3.33Å; H656-F658 PolarHBondContact O-N 2.91Å; H656-C659 PolarHBondContact O-N 3.1Å; H656-L660 WeakPolarHBondContact O-CG 3.22Å; H656-L660 PolarHBondContact O-N 3.28Å
657L98.1Very high94.7Very high1 Ų123.6 Ų23.61%0.00511%0.112CC..Hα-helixtrans-63-39.2176.8-65.5-176.8000112.1T182 Y186 I653 D654 L660 Y661 F673 L674 V677T182-L657 HydrophobicContact CG2-CD2 3.73Å; T182-L657 HydrophobicContact CG2-CG 3.81Å; Y186-L657 HydrophobicContact CD2-CD1 4.3Å; Y186-L657 HydrophobicContact CG-CD1 4.42Å; I653-L657 HydrophobicContact CG2-CD1 3.71Å; I653-L657 HydrophobicContact CG2-CG 4.26Å; I653-L657 PolarHBondContact O-N 2.98Å; I653-L657 VanDerWaalsContact O-N 3.09Å; D654-L657 PolarHBondContact O-N 3.35Å; L657-L660 HydrophobicContact CD2-CD1 4.28Å; L657-L660 PolarHBondContact O-N 2.83Å; L657-Y661 WeakPolarHBondContact O-CB 3.38Å; L657-Y661 PolarHBondContact O-N 3.48Å; L657-F673 HydrophobicContact CD2-CE1 4Å; L657-L674 HydrophobicContact CB-CD2 4.48Å; L657-L674 HydrophobicContact CD2-CD2 4.17Å; L657-V677 HydrophobicContact CD1-CB 4.47Å; L657-V677 HydrophobicContact CD1-CG1 3.52Å
658F97Very high94.6Very high19 Ų1928 Ų288%0.08315%0.148CC..Hα-helixtrans-56.4-51.3172.1163.4-101.6000111.8W235 W236 Y239 I240 D654 H656 L660 Y661 V662W235-F658 HydrophobicContact CB-CE1 4.04Å; W235-F658 HydrophobicContact CB-CZ 4.3Å; W236-F658 HydrophobicContact CE3-CD1 4.09Å; W236-F658 HydrophobicContact CE3-CE1 4.09Å; W236-F658 HydrophobicContact CE3-CG 4.46Å; W236-F658 HydrophobicContact CE3-CZ 4.46Å; W236-F658 HydrophobicContact CZ3-CG 4.48Å; Y239-F658 HydrophobicContact CD2-CZ 4.21Å; Y239-F658 HydrophobicContact CG-CZ 4.4Å; I240-F658 HydrophobicContact CD1-CD2 4.17Å; I240-F658 HydrophobicContact CD1-CE2 3.77Å; I240-F658 HydrophobicContact CD1-CZ 4.34Å; I240-F658 HydrophobicContact CG1-CE2 4.3Å; I240-F658 HydrophobicContact CG1-CZ 4.38Å; D654-F658 VanDerWaalsContact O-CB 3.3Å; D654-F658 WeakPolarHBondContact O-CB 3.36Å; D654-F658 PolarHBondContact O-N 3.33Å; H656-F658 VanDerWaalsContact C-N 3.33Å; H656-F658 PolarHBondContact O-N 2.91Å; F658-L660 VanDerWaalsContact C-N 3.34Å; F658-L660 PolarHBondContact O-N 3.24Å; F658-Y661 WeakPolarHBondContact O-CB 3.49Å; F658-Y661 PolarHBondContact O-N 2.85Å; F658-Y661 VanDerWaalsContact O-N 3.12Å; F658-V662 HydrophobicContact CD2-CG2 4.31Å; F658-V662 HydrophobicContact CE1-CG2 4.18Å; F658-V662 HydrophobicContact CE2-CG2 3.79Å; F658-V662 HydrophobicContact CZ-CG2 3.71Å; F658-V662 WeakPolarHBondContact O-CG2 3.24Å; F658-V662 PolarHBondContact O-N 2.9Å
659C96.6Very high94.4Very high0 Ų029.2 Ų29.20%016%0.156CC..Hα-helixtrans-65.7-35.8179.9-70.90000112.7L221 Y231 W235 R655 H656 Y661 V662 V663L221-C659 HydrophobicContact CD1-CB 3.7Å; L221-C659 HydrophobicContact CD2-CB 3.94Å; Y231-C659 HydrophobicContact CD2-CB 4.43Å; Y231-C659 HydrophobicContact CE2-CB 4.31Å; W235-C659 HydrophobicContact CE3-CB 4.14Å; W235-C659 HydrophobicContact CZ3-CB 4.14Å; R655-C659 PolarHBondContact O-N 2.93Å; R655-C659 PolarHBondContact O-SG 2.82Å; R655-C659 VanDerWaalsContact O-SG 3.35Å; H656-C659 PolarHBondContact O-N 3.1Å; C659-Y661 VanDerWaalsContact C-N 3.3Å; C659-Y661 PolarHBondContact O-N 3.31Å; C659-V662 PolarHBondContact O-N 3.46Å; C659-V663 WeakPolarHBondContact O-CG2 3.4Å; C659-V663 PolarHBondContact O-N 3.49Å
660L97.1Very high94.2Very high0 Ų036.2 Ų36.20%019%0.188CC..Hα-helixtrans-62.6-39.6172.8-67.7170.1000111F209 L217 L221 H656 L657 F658 V663 S664 L674F209-L660 HydrophobicContact CE1-CD1 4.28Å; F209-L660 HydrophobicContact CZ-CD1 4.13Å; L217-L660 HydrophobicContact CB-CD2 3.65Å; L217-L660 HydrophobicContact CD1-CB 4.38Å; L221-L660 HydrophobicContact CD2-CD2 4.06Å; L221-L660 HydrophobicContact CD2-CG 4.3Å; H656-L660 WeakPolarHBondContact O-CG 3.22Å; H656-L660 PolarHBondContact O-N 3.28Å; L657-L660 HydrophobicContact CD2-CD1 4.28Å; L657-L660 PolarHBondContact O-N 2.83Å; F658-L660 VanDerWaalsContact C-N 3.34Å; F658-L660 PolarHBondContact O-N 3.24Å; L660-V663 PolarHBondContact O-N 3.12Å; L660-S664 PolarHBondContact O-N 3.39Å; L660-L674 HydrophobicContact CB-CD1 4.3Å; L660-L674 HydrophobicContact CB-CD2 4.37Å
661Y95.3Very high94.1Very high74 Ų7436.5 Ų36.529%0.2919%0.189SC..Hα-helixtrans-63.7-44.5174.2176.9-102.9000112.6L657 F658 C659 V663 S664 K665 L674 L678L657-Y661 WeakPolarHBondContact O-CB 3.38Å; L657-Y661 PolarHBondContact O-N 3.48Å; F658-Y661 WeakPolarHBondContact O-CB 3.49Å; F658-Y661 PolarHBondContact O-N 2.85Å; F658-Y661 VanDerWaalsContact O-N 3.12Å; C659-Y661 VanDerWaalsContact C-N 3.3Å; C659-Y661 PolarHBondContact O-N 3.31Å; Y661-V663 VanDerWaalsContact C-N 3.31Å; Y661-V663 PolarHBondContact O-N 3.44Å; Y661-S664 WeakPolarHBondContact O-CA 3.35Å; Y661-S664 WeakPolarHBondContact O-CB 3.08Å; Y661-S664 PolarHBondContact O-N 2.86Å; Y661-S664 PolarHBondContact O-OG 3.33Å; Y661-K665 HydrophobicContact CE1-CG 4.18Å; Y661-K665 HydrophobicContact CE2-CD 4.46Å; Y661-K665 PolarHBondContact O-N 3.36Å; Y661-K665 WeakPolarHBondContact OH-CE 3.32Å; Y661-L674 HydrophobicContact CD2-CB 4Å; Y661-L678 HydrophobicContact CD1-CD1 3.72Å; Y661-L678 HydrophobicContact CD2-CD1 3.8Å; Y661-L678 HydrophobicContact CE1-CD1 4.44Å; Y661-L678 HydrophobicContact CG-CD1 3.33Å
662V91.5Very high94.1Very high7 Ų739.2 Ų39.24%0.04220%0.204CC..Hα-helixtrans-56.8-46174.2172.90000110.9W235 Y239 F658 C659 S664 K665 Y666W235-V662 HydrophobicContact CD2-CB 4.4Å; W235-V662 HydrophobicContact CD2-CG1 3.68Å; W235-V662 HydrophobicContact CE3-CB 4.02Å; W235-V662 HydrophobicContact CE3-CG1 3.75Å; W235-V662 HydrophobicContact CG-CG1 4.23Å; W235-V662 HydrophobicContact CH2-CG1 4.09Å; W235-V662 HydrophobicContact CZ2-CG1 4.04Å; W235-V662 HydrophobicContact CZ3-CB 4.18Å; W235-V662 HydrophobicContact CZ3-CG1 3.95Å; Y239-V662 HydrophobicContact CD2-CG1 4.34Å; Y239-V662 HydrophobicContact CD2-CG2 4.02Å; Y239-V662 HydrophobicContact CE2-CG1 3.75Å; Y239-V662 HydrophobicContact CE2-CG2 4.25Å; F658-V662 HydrophobicContact CD2-CG2 4.31Å; F658-V662 HydrophobicContact CE1-CG2 4.18Å; F658-V662 HydrophobicContact CE2-CG2 3.79Å; F658-V662 HydrophobicContact CZ-CG2 3.71Å; F658-V662 WeakPolarHBondContact O-CG2 3.24Å; F658-V662 PolarHBondContact O-N 2.9Å; C659-V662 PolarHBondContact O-N 3.46Å; V662-S664 VanDerWaalsContact C-N 3.32Å; V662-S664 PolarHBondContact O-N 3.4Å; V662-K665 PolarHBondContact O-N 2.86Å; V662-Y666 HydrophobicContact CG1-CD2 3.83Å; V662-Y666 HydrophobicContact CG1-CE2 3.49Å; V662-Y666 VanDerWaalsContact CG1-CE2 3.49Å; V662-Y666 VanDerWaalsContact O-CD2 3.27Å; V662-Y666 WeakPolarHBondContact O-CD2 3.43Å; V662-Y666 PolarHBondContact O-N 3.41Å; V662-Y666 VanDerWaalsContact O-N 3.09Å
663V91.4Very high94.1Very high7 Ų739.1 Ų39.14%0.04220%0.202CC..Hα-helixtrans-60.2-41.8174.6176.50000111.4L217 Y220 W235 C659 L660 Y661 K665 Y666 L667L217-V663 HydrophobicContact CB-CG1 4.31Å; L217-V663 HydrophobicContact CD2-CB 4.3Å; L217-V663 HydrophobicContact CD2-CG1 3.72Å; Y220-V663 HydrophobicContact CD2-CG1 4.24Å; Y220-V663 HydrophobicContact CG-CG1 4.25Å; W235-V663 HydrophobicContact CH2-CG2 3.71Å; W235-V663 HydrophobicContact CZ3-CG2 3.93Å; C659-V663 WeakPolarHBondContact O-CG2 3.4Å; C659-V663 PolarHBondContact O-N 3.49Å; L660-V663 PolarHBondContact O-N 3.12Å; Y661-V663 VanDerWaalsContact C-N 3.31Å; Y661-V663 PolarHBondContact O-N 3.44Å; V663-K665 VanDerWaalsContact C-N 3.25Å; V663-K665 PolarHBondContact O-N 2.86Å; V663-Y666 PolarHBondContact O-N 3.41Å; V663-L667 HydrophobicContact CG1-CD1 4.03Å; V663-L667 HydrophobicContact CG1-CG 4.32Å; V663-L667 WeakPolarHBondContact O-CG 3.29Å; V663-L667 PolarHBondContact O-N 2.77Å
664S92.2Very high94Very high1 Ų138.5 Ų38.51%0.00720%0.199CC..Hα-helixtrans-59.6-37.4178790000112.2L660 Y661 V662 L667 A668 V669L660-S664 PolarHBondContact O-N 3.39Å; Y661-S664 WeakPolarHBondContact O-CA 3.35Å; Y661-S664 WeakPolarHBondContact O-CB 3.08Å; Y661-S664 PolarHBondContact O-N 2.86Å; Y661-S664 PolarHBondContact O-OG 3.33Å; V662-S664 VanDerWaalsContact C-N 3.32Å; V662-S664 PolarHBondContact O-N 3.4Å; S664-L667 CarbonylContact O-C 3.59Å; S664-L667 PolarHBondContact O-N 2.89Å; S664-A668 PolarHBondContact O-N 2.84Å; S664-A668 VanDerWaalsContact O-N 3.12Å; S664-V669 WeakPolarHBondContact O-CG2 3.25Å; S664-V669 PolarHBondContact O-N 3.37Å
665K89.7Confident93.8Very high110 Ų11045 Ų4548%0.47823%0.227SC..Hα-helixtrans-68.4-41.9175.6-64.4-55-177.6-178.70112.6Y661 V662 V663 L667 A668Y661-K665 HydrophobicContact CE1-CG 4.18Å; Y661-K665 HydrophobicContact CE2-CD 4.46Å; Y661-K665 PolarHBondContact O-N 3.36Å; Y661-K665 WeakPolarHBondContact OH-CE 3.32Å; V662-K665 PolarHBondContact O-N 2.86Å; V663-K665 VanDerWaalsContact C-N 3.25Å; V663-K665 PolarHBondContact O-N 2.86Å; K665-L667 VanDerWaalsContact C-N 3.26Å; K665-L667 PolarHBondContact O-N 2.95Å; K665-A668 PolarHBondContact O-N 3.26Å
666Y85.7Confident93.6Very high137 Ų13746.7 Ų46.754%0.53724%0.235SC..Hα-helixtrans-62.8-33.2173.8-78.3-62.9000113.3W235 Y239 V662 V663 A668W235-Y666 HydrophobicContact CZ2-CD2 4.33Å; W235-Y666 AromaticContact CZ2-CE2 3.84Å; W235-Y666 HydrophobicContact CZ2-CE2 3.84Å; Y239-Y666 PolarHBondContact OH-OH 3.17Å; V662-Y666 HydrophobicContact CG1-CD2 3.83Å; V662-Y666 HydrophobicContact CG1-CE2 3.49Å; V662-Y666 VanDerWaalsContact CG1-CE2 3.49Å; V662-Y666 VanDerWaalsContact O-CD2 3.27Å; V662-Y666 WeakPolarHBondContact O-CD2 3.43Å; V662-Y666 PolarHBondContact O-N 3.41Å; V662-Y666 VanDerWaalsContact O-N 3.09Å; V663-Y666 PolarHBondContact O-N 3.41Å; Y666-A668 VanDerWaalsContact C-N 3.27Å
667L86.8Confident93.3Very high45 Ų4547 Ų4724%0.23624%0.237CC..THydrogen-bonded Turntrans-84.2-0.8176.2-63.5-178.8000113.3L217 Y220 V663 S664 K665 V669L217-L667 HydrophobicContact CD2-CD1 3.76Å; Y220-L667 HydrophobicContact CD2-CD1 3.84Å; Y220-L667 HydrophobicContact CE1-CD2 4.47Å; Y220-L667 HydrophobicContact CE2-CD1 3.66Å; Y220-L667 HydrophobicContact CE2-CD2 4.03Å; Y220-L667 HydrophobicContact CE2-CG 4.45Å; V663-L667 HydrophobicContact CG1-CD1 4.03Å; V663-L667 HydrophobicContact CG1-CG 4.32Å; V663-L667 WeakPolarHBondContact O-CG 3.29Å; V663-L667 PolarHBondContact O-N 2.77Å; S664-L667 CarbonylContact O-C 3.59Å; S664-L667 PolarHBondContact O-N 2.89Å; K665-L667 VanDerWaalsContact C-N 3.26Å; K665-L667 PolarHBondContact O-N 2.95Å; L667-V669 HydrophobicContact CB-CG1 4.26Å; L667-V669 HydrophobicContact CB-CG2 3.97Å; L667-V669 PolarHBondContact O-N 2.86Å
668A93.5Very high92.9Very high93 Ų9350.1 Ų50.177%0.76925%0.253SS*.THydrogen-bonded Turntrans50.838.6-17400000113.1S664 K665 Y666S664-A668 PolarHBondContact O-N 2.84Å; S664-A668 VanDerWaalsContact O-N 3.12Å; K665-A668 PolarHBondContact O-N 3.26Å; Y666-A668 VanDerWaalsContact C-N 3.27Å
669V91.8Very high92.4Very high37 Ų3753 Ų5322%0.22428%0.276CS..  trans-110.4137.5176.8-63.30000110.3L213 L217 S664 L667L213-V669 HydrophobicContact CD1-CG2 3.97Å; L213-V669 HydrophobicContact CD2-CG2 4.32Å; L217-V669 HydrophobicContact CD2-CG2 4.31Å; S664-V669 WeakPolarHBondContact O-CG2 3.25Å; S664-V669 PolarHBondContact O-N 3.37Å; L667-V669 HydrophobicContact CB-CG1 4.26Å; L667-V669 HydrophobicContact CB-CG2 3.97Å; L667-V669 PolarHBondContact O-N 2.86Å
670E92.3Very high91.8Very high163 Ų16355 Ų5576%0.76229%0.285SS*.  trans-91.4144.5175.7-60.8-158149.800111.4
671S94.2Very high91.6Very high11 Ų1157.2 Ų57.28%0.07730%0.3CS..  trans-132.9111.9174178.30000108.4F209 F673 L674 K675F209-S671 WeakPolarHBondContact CD2-OG 3.38Å; S671-F673 PolarHBondContact O-N 3.44Å; S671-L674 PolarHBondContact O-N 2.79Å; S671-L674 PolarHBondContact OG-N 3.31Å; S671-K675 WeakPolarHBondContact O-CB 3.31Å; S671-K675 PolarHBondContact O-N 3.22Å
672P95.6Very high91.6Very high81 Ų8156.4 Ų56.453%0.52630%0.296SS..Hα-helixtrans-56.5-41.1174.9-26.135000111.8L205 K675 E676L205-P672 HydrophobicContact CD1-CB 4.43Å; L205-P672 HydrophobicContact CD2-CB 4.06Å; P672-K675 PolarHBondContact O-N 2.89Å; P672-E676 WeakPolarHBondContact O-CB 3.48Å; P672-E676 PolarHBondContact O-N 3.2Å
673F97.2Very high91.8Very high3 Ų359.6 Ų59.61%0.01331%0.308CS..Hα-helixtrans-58.1-57.2175.8176.4-108000112.5V183 Y186 M202 L205 A206 F209 L657 S671 K675 E676 V677V183-F673 HydrophobicContact CG2-CE1 4.21Å; V183-F673 HydrophobicContact CG2-CZ 4.17Å; Y186-F673 AromaticContact CD1-CE2 3.68Å; Y186-F673 HydrophobicContact CD1-CE2 3.68Å; Y186-F673 AromaticContact CD1-CZ 3.76Å; Y186-F673 HydrophobicContact CD1-CZ 3.76Å; Y186-F673 AromaticContact CE1-CE2 3.55Å; Y186-F673 HydrophobicContact CE1-CE2 3.55Å; Y186-F673 HydrophobicContact CE1-CZ 4.04Å; Y186-F673 HydrophobicContact CG-CZ 4.35Å; M202-F673 HydrophobicContact SD-CD2 3.82Å; M202-F673 HydrophobicContact SD-CE2 3.93Å; L205-F673 HydrophobicContact CB-CB 4.24Å; L205-F673 HydrophobicContact CB-CD2 4.4Å; A206-F673 HydrophobicContact CB-CD2 3.84Å; A206-F673 HydrophobicContact CB-CE2 3.53Å; A206-F673 HydrophobicContact CB-CZ 4.26Å; F209-F673 HydrophobicContact CB-CB 3.84Å; F209-F673 HydrophobicContact CB-CD1 3.81Å; F209-F673 HydrophobicContact CB-CG 3.93Å; F209-F673 AromaticContact CD1-CD1 3.36Å; F209-F673 HydrophobicContact CD1-CD1 3.36Å; F209-F673 AromaticContact CD1-CE1 3.6Å; F209-F673 HydrophobicContact CD1-CE1 3.6Å; F209-F673 HydrophobicContact CD1-CG 4.32Å; F209-F673 HydrophobicContact CD2-CD1 4.13Å; F209-F673 AromaticContact CE1-CD1 3.92Å; F209-F673 HydrophobicContact CE1-CD1 3.92Å; F209-F673 AromaticContact CE1-CE1 3.96Å; F209-F673 HydrophobicContact CE1-CE1 3.96Å; F209-F673 HydrophobicContact CG-CB 4.21Å; F209-F673 AromaticContact CG-CD1 3.48Å; F209-F673 HydrophobicContact CG-CD1 3.48Å; F209-F673 VanDerWaalsContact CG-CD1 3.48Å; F209-F673 HydrophobicContact CG-CE1 4.2Å; F209-F673 HydrophobicContact CG-CG 4.1Å; L657-F673 HydrophobicContact CD2-CE1 4Å; S671-F673 PolarHBondContact O-N 3.44Å; F673-K675 VanDerWaalsContact C-N 3.3Å; F673-K675 PolarHBondContact O-N 3.36Å; F673-E676 PolarHBondContact O-N 2.95Å; F673-V677 HydrophobicContact CD1-CG2 4.37Å; F673-V677 HydrophobicContact CD2-CG2 3.76Å; F673-V677 HydrophobicContact CE1-CG2 4.08Å; F673-V677 HydrophobicContact CE2-CG2 3.42Å; F673-V677 VanDerWaalsContact CE2-CG2 3.42Å; F673-V677 HydrophobicContact CG-CG2 4.23Å; F673-V677 HydrophobicContact CZ-CG2 3.6Å; F673-V677 WeakPolarHBondContact O-CG2 3.46Å; F673-V677 PolarHBondContact O-N 2.79Å
674L95.3Very high92.2Very high1 Ų159.2 Ų59.21%0.00531%0.306CS..Hα-helixtrans-65.7-34.2-177.1-64174.1000112.4F209 L217 L657 L660 Y661 S671 E676 L678F209-L674 HydrophobicContact CD2-CG 4.38Å; F209-L674 HydrophobicContact CE1-CD2 4.27Å; F209-L674 HydrophobicContact CE2-CD1 3.63Å; F209-L674 HydrophobicContact CE2-CD2 4.2Å; F209-L674 HydrophobicContact CE2-CG 3.77Å; F209-L674 HydrophobicContact CZ-CD1 3.87Å; F209-L674 HydrophobicContact CZ-CD2 3.82Å; F209-L674 HydrophobicContact CZ-CG 3.92Å; L217-L674 HydrophobicContact CD1-CD1 3.79Å; L657-L674 HydrophobicContact CB-CD2 4.48Å; L657-L674 HydrophobicContact CD2-CD2 4.17Å; L660-L674 HydrophobicContact CB-CD1 4.3Å; L660-L674 HydrophobicContact CB-CD2 4.37Å; Y661-L674 HydrophobicContact CD2-CB 4Å; S671-L674 PolarHBondContact O-N 2.79Å; S671-L674 PolarHBondContact OG-N 3.31Å; L674-E676 VanDerWaalsContact C-N 3.33Å; L674-L678 WeakPolarHBondContact O-CB 3.45Å; L674-L678 WeakPolarHBondContact O-CG 3.14Å; L674-L678 PolarHBondContact O-N 2.91Å
675K92.6Very high92.4Very high147 Ų14759.6 Ų59.664%0.63931%0.308SS*.Hα-helixtrans-61.2-44.7175.3-177.4178.7179.4179.10110.9S671 P672 F673 S679S671-K675 WeakPolarHBondContact O-CB 3.31Å; S671-K675 PolarHBondContact O-N 3.22Å; P672-K675 PolarHBondContact O-N 2.89Å; F673-K675 VanDerWaalsContact C-N 3.3Å; F673-K675 PolarHBondContact O-N 3.36Å; K675-S679 WeakPolarHBondContact O-CB 3.16Å; K675-S679 PolarHBondContact O-N 2.94Å; K675-S679 PolarHBondContact O-OG 2.91Å
676E93.4Very high92.9Very high43 Ų4354.4 Ų54.420%0.20129%0.286CS..Hα-helixtrans-73.4-48.2-177-165.9172.5151.400112R201 M202 P672 F673 L674 L678 S679R201-E676 IonicContact CZ-OE1 2.88Å; R201-E676 IonicContact CZ-OE2 3Å; R201-E676 IonicContact NH1-OE1 2.84Å; R201-E676 IonicContact NH1-OE2 3.69Å; R201-E676 PolarHBondContact NH1-OE2 3.35Å; R201-E676 IonicContact NH2-OE1 3.2Å; R201-E676 PolarHBondContact NH2-OE1 2.67Å; R201-E676 IonicContact NH2-OE2 3.24Å; R201-E676 PolarHBondContact NH2-OE2 2.88Å; M202-E676 HydrophobicContact CE-CB 4.12Å; M202-E676 HydrophobicContact CE-CG 3.7Å; M202-E676 WeakPolarHBondContact CE-OE1 3.29Å; P672-E676 WeakPolarHBondContact O-CB 3.48Å; P672-E676 PolarHBondContact O-N 3.2Å; F673-E676 PolarHBondContact O-N 2.95Å; L674-E676 VanDerWaalsContact C-N 3.33Å; E676-L678 PolarHBondContact O-N 3.42Å; E676-L678 VanDerWaalsContact O-N 3.16Å; E676-S679 PolarHBondContact O-N 3.27Å; E676-S679 PolarHBondContact O-OG 2.93Å
677V91.8Very high93.4Very high6 Ų648.8 Ų48.84%0.03627%0.266CS..Hα-helixtrans-59.2-33.1-177.8177.70000112.8Y186 L657 F673Y186-V677 HydrophobicContact CD1-CG2 4.35Å; Y186-V677 HydrophobicContact CD2-CG1 3.69Å; Y186-V677 HydrophobicContact CD2-CG2 4.37Å; Y186-V677 HydrophobicContact CE1-CG2 3.7Å; Y186-V677 HydrophobicContact CE2-CB 4Å; Y186-V677 HydrophobicContact CE2-CG1 3.3Å; Y186-V677 HydrophobicContact CE2-CG2 3.72Å; Y186-V677 WeakPolarHBondContact OH-CG2 3.44Å; L657-V677 HydrophobicContact CD1-CB 4.47Å; L657-V677 HydrophobicContact CD1-CG1 3.52Å; F673-V677 HydrophobicContact CD1-CG2 4.37Å; F673-V677 HydrophobicContact CD2-CG2 3.76Å; F673-V677 HydrophobicContact CE1-CG2 4.08Å; F673-V677 HydrophobicContact CE2-CG2 3.42Å; F673-V677 VanDerWaalsContact CE2-CG2 3.42Å; F673-V677 HydrophobicContact CG-CG2 4.23Å; F673-V677 HydrophobicContact CZ-CG2 3.6Å; F673-V677 WeakPolarHBondContact O-CG2 3.46Å; F673-V677 PolarHBondContact O-N 2.79Å
678L89.1Confident93.7Very high67 Ų6749 Ų4935%0.35127%0.266SS..THydrogen-bonded Turntrans-91.3-2.3-179.3-63.9173000113.5Y661 L674 E676Y661-L678 HydrophobicContact CD1-CD1 3.72Å; Y661-L678 HydrophobicContact CD2-CD1 3.8Å; Y661-L678 HydrophobicContact CE1-CD1 4.44Å; Y661-L678 HydrophobicContact CG-CD1 3.33Å; L674-L678 WeakPolarHBondContact O-CB 3.45Å; L674-L678 WeakPolarHBondContact O-CG 3.14Å; L674-L678 PolarHBondContact O-N 2.91Å; E676-L678 PolarHBondContact O-N 3.42Å; E676-L678 VanDerWaalsContact O-N 3.16Å
679S87.1Confident93.3Very high81 Ų8145.4 Ų45.457%0.56623%0.234SC*.THydrogen-bonded Turntrans-93.5-16.5179.168.80000113.9K675 E676 P681K675-S679 WeakPolarHBondContact O-CB 3.16Å; K675-S679 PolarHBondContact O-N 2.94Å; K675-S679 PolarHBondContact O-OG 2.91Å; E676-S679 PolarHBondContact O-N 3.27Å; E676-S679 PolarHBondContact O-OG 2.93Å; S679-P681 WeakPolarHBondContact O-CD 3.41Å
680E85.3Confident92.6Very high41 Ų4146.1 Ų46.119%0.19224%0.24CC..SBendtrans-69.4123.8-179.9-69.9179.7-170.900111M194 L587M194-E680 VanDerWaalsContact CE-OE1 3.29Å; M194-E680 WeakPolarHBondContact CE-OE1 3.28Å; L587-E680 HydrophobicContact CD2-CB 3.94Å
681P91.8Very high91.7Very high47 Ų4740.3 Ų40.331%0.30521%0.213SC..  trans-76.2142.5-179.530.3-34.6000111.8S679 R683 A713S679-P681 WeakPolarHBondContact O-CD 3.41Å; P681-R683 VanDerWaalsContact C-N 3.35Å; P681-R683 HydrophobicContact CG-CG 4.44Å; P681-R683 PolarHBondContact O-N 3.16Å; P681-A713 HydrophobicContact CB-CB 4.07Å
682W95.4Very high90.6Very high57 Ų5742.7 Ų42.722%0.21622%0.223CC..  trans-80.279.5174.3-60.2101.6000110.4L587 Y589 T604 R606 D654 L684 V712L587-W682 HydrophobicContact CB-CE3 4.39Å; L587-W682 HydrophobicContact CD1-CE3 4.24Å; L587-W682 HydrophobicContact CD1-CH2 4.13Å; L587-W682 HydrophobicContact CD1-CZ3 3.65Å; L587-W682 HydrophobicContact CD2-CD2 3.8Å; L587-W682 HydrophobicContact CD2-CE3 3.54Å; L587-W682 HydrophobicContact CD2-CH2 3.82Å; L587-W682 HydrophobicContact CD2-CZ2 4.04Å; L587-W682 HydrophobicContact CD2-CZ3 3.58Å; L587-W682 HydrophobicContact CG-CD2 4.15Å; L587-W682 HydrophobicContact CG-CE3 3.39Å; L587-W682 HydrophobicContact CG-CH2 4.02Å; L587-W682 HydrophobicContact CG-CZ3 3.33Å; Y589-W682 VanDerWaalsContact CB-CE3 3.48Å; Y589-W682 HydrophobicContact CD2-CD2 4.16Å; Y589-W682 HydrophobicContact CD2-CE3 4.33Å; Y589-W682 HydrophobicContact CD2-CZ2 4.43Å; Y589-W682 HydrophobicContact CG-CD2 4.44Å; Y589-W682 HydrophobicContact CG-CE3 4.42Å; T604-W682 HydrophobicContact CG2-CH2 3.7Å; T604-W682 HydrophobicContact CG2-CZ2 4.27Å; T604-W682 HydrophobicContact CG2-CZ3 4.02Å; R606-W682 HydrophobicContact CG-CH2 4.04Å; R606-W682 HydrophobicContact CG-CZ3 4.16Å; D654-W682 WeakPolarHBondContact OD1-CH2 3.45Å; D654-W682 VanDerWaalsContact OD1-CZ2 3.24Å; D654-W682 WeakPolarHBondContact OD1-CZ2 3.48Å; W682-L684 PolarHBondContact O-N 2.96Å; W682-V712 HydrophobicContact CB-CG2 3.81Å; W682-V712 WeakPolarHBondContact O-CG2 3.37Å
683R96.4Very high89.6Confident73 Ų7343.2 Ų43.228%0.27522%0.218SC..SBendtrans-65.2-17.4-177.7-70.5-179.8174.385.67.7114.3L587 P681 D715 G716 Y717L587-R683 PolarHBondContact O-N 2.86Å; P681-R683 VanDerWaalsContact C-N 3.35Å; P681-R683 HydrophobicContact CG-CG 4.44Å; P681-R683 PolarHBondContact O-N 3.16Å; R683-D715 IonicContact CZ-OD1 2.68Å; R683-D715 IonicContact CZ-OD2 3.03Å; R683-D715 VanDerWaalsContact NE-CG 3.33Å; R683-D715 IonicContact NE-OD1 3.23Å; R683-D715 PolarHBondContact NE-OD1 3.21Å; R683-D715 IonicContact NE-OD2 2.79Å; R683-D715 PolarHBondContact NE-OD2 2.95Å; R683-D715 IonicContact NH2-OD1 2.85Å; R683-D715 IonicContact NH2-OD2 3.47Å; R683-D715 PolarHBondContact NH2-OD2 3.14Å; R683-G716 CarbonylContact O-C 3.46Å; R683-G716 WeakPolarHBondContact O-CA 3.28Å; R683-Y717 PolarHBondContact O-N 3.45Å
684L98.1Very high88.8Confident0 Ų044 Ų440%022%0.222CC..EExtended strand (participates in β ladder)trans-127.3104.7166.8-178.159.8000108.9L574 H578 L587 T588 Y589 W682 T686 V719 F747L574-L684 HydrophobicContact CB-CD2 4.34Å; H578-L684 HydrophobicContact CB-CD2 4.23Å; L587-L684 PolarHBondContact O-N 3.42Å; T588-L684 CarbonylContact C-O 3.56Å; T588-L684 VanDerWaalsContact CA-O 3.28Å; T588-L684 WeakPolarHBondContact CA-O 3.32Å; T588-L684 HydrophobicContact CG2-CB 4.01Å; T588-L684 HydrophobicContact CG2-CD2 3.73Å; T588-L684 HydrophobicContact CG2-CG 3.81Å; Y589-L684 PolarHBondContact N-O 3.24Å; W682-L684 PolarHBondContact O-N 2.96Å; L684-T686 HydrophobicContact CD1-CG2 4.04Å; L684-T686 HydrophobicContact CD2-CG2 4.43Å; L684-T686 HydrophobicContact CG-CG2 3.79Å; L684-V719 HydrophobicContact CD1-CG2 3.8Å; L684-F747 HydrophobicContact CD1-CE1 3.94Å; L684-F747 HydrophobicContact CD1-CZ 4.01Å
685S98.3Very high88.2Confident9 Ų947.1 Ų47.16%0.06324%0.239CC..EExtended strand (participates in β ladder)trans-105.2123.4178-178.70000110.7V712 Y717 G718 V719S685-V712 VanDerWaalsContact CB-CG2 3.42Å; S685-Y717 PolarHBondContact N-O 2.98Å; S685-G718 CarbonylContact O-C 3.57Å; S685-G718 WeakPolarHBondContact O-CA 3.39Å; S685-V719 PolarHBondContact O-N 3.45Å
686T98.2Very high87.8Confident1 Ų141 Ų411%0.00621%0.213CC..EExtended strand (participates in β ladder)trans-130.8149.3-169.274.70000112.6Q571 L574 T588 Y589 E590 A591 L684 V719Q571-T686 PolarHBondContact NE2-OG1 3.4Å; L574-T686 HydrophobicContact CD1-CG2 3.85Å; T588-T686 HydrophobicContact CG2-CG2 4.28Å; Y589-T686 WeakPolarHBondContact O-CA 3.45Å; Y589-T686 WeakPolarHBondContact O-CB 3.34Å; Y589-T686 PolarHBondContact O-N 2.81Å; Y589-T686 PolarHBondContact O-OG1 3.49Å; E590-T686 WeakPolarHBondContact CA-O 3.28Å; E590-T686 WeakPolarHBondContact CA-OG1 3.49Å; E590-T686 WeakPolarHBondContact CB-OG1 3.41Å; A591-T686 PolarHBondContact N-O 3.14Å; L684-T686 HydrophobicContact CD1-CG2 4.04Å; L684-T686 HydrophobicContact CD2-CG2 4.43Å; L684-T686 HydrophobicContact CG-CG2 3.79Å; T686-V719 CarbonylContact C-O 3.56Å; T686-V719 WeakPolarHBondContact CA-O 3.31Å; T686-V719 HydrophobicContact CG2-CB 4.29Å
687S96.3Very high87.3Confident19 Ų1947.2 Ų47.213%0.13324%0.239CC..EExtended strand (participates in β ladder)trans-152.9142.7166.764.30000112.9F709 V719 S720 Y721S687-F709 VanDerWaalsContact OG-CE1 3.24Å; S687-F709 WeakPolarHBondContact OG-CE1 3.36Å; S687-V719 PolarHBondContact N-O 2.91Å; S687-S720 WeakPolarHBondContact O-CA 3.35Å; S687-S720 PolarHBondContact O-OG 3.43Å; S687-Y721 PolarHBondContact O-N 2.72Å; S687-Y721 VanDerWaalsContact O-N 3.1Å
688Q93.5Very high87Confident50 Ų5054.7 Ų54.723%0.23427%0.271CS..EExtended strand (participates in β ladder)trans-90130.9166.6-173.1-177.146.700110.3P690 Y721Q688-P690 WeakPolarHBondContact O-CD 3.33Å; Q688-Y721 WeakPolarHBondContact CA-O 3.46Å; Q688-Y721 HydrophobicContact CB-CD2 4.26Å; Q688-Y721 HydrophobicContact CB-CE2 3.63Å; Q688-Y721 HydrophobicContact CG-CD2 4.08Å; Q688-Y721 HydrophobicContact CG-CE2 3.69Å
689T84.9Confident86.9Confident16 Ų1653.2 Ų53.210%0.09826%0.264CS..  trans-104.2104.3165.9-57.90000109.2Y721 I722T689-Y721 PolarHBondContact N-O 2.91Å; T689-I722 VanDerWaalsContact O-CG1 3.28Å; T689-I722 WeakPolarHBondContact O-CG1 3.38Å
690P77.3Confident86.9Confident53 Ų5353.6 Ų53.634%0.34427%0.265SS..  trans-76.1136.6-176.929.4-33.5000111.1Q688Q688-P690 WeakPolarHBondContact O-CD 3.33Å
691Q74.6Confident86.9Confident41 Ų4154.8 Ų54.819%0.19227%0.27CS..  trans-72130.1168.2-163.9172.513.500110.1E486 I722 L724E486-Q691 VanDerWaalsContact OE1-CA 3.23Å; E486-Q691 WeakPolarHBondContact OE1-CA 3.46Å; Q691-I722 HydrophobicContact CB-CD1 4.35Å; Q691-L724 PolarHBondContact OE1-O 3.23Å
692Q70.2Confident86.7Confident60 Ų6052.6 Ų52.628%0.2826%0.256SS..  trans-109.1-41.2-169.8-62.4-178.915.200113.5P479 H483 E486P479-Q692 PolarHBondContact O-NE2 3.32Å; H483-Q692 PolarHBondContact CD2-OE1 3.24Å; E486-Q692 PolarHBondContact OE1-N 3.35Å; E486-Q692 PolarHBondContact OE2-N 3.05Å
693H74Confident86.4Confident92 Ų9250.5 Ų50.543%0.42625%0.249SC..SBendtrans-124.5-28.5-159.2-76.6-158.1000115.2H483 E486 N487 D695H483-H693 AromaticContact CD2-CE1 3.53Å; H483-H693 AromaticContact CD2-NE2 3.53Å; H483-H693 AromaticContact CE1-CE1 3.4Å; H483-H693 PolarHBondContact CE1-CE1 2.95Å; H483-H693 VanDerWaalsContact CE1-CE1 3.4Å; H483-H693 AromaticContact NE2-CE1 3Å; H483-H693 PolarHBondContact NE2-CE1 3.47Å; H483-H693 AromaticContact NE2-NE2 3.37Å; H483-H693 PolarHBondContact NE2-NE2 2.86Å; E486-H693 PolarHBondContact OE2-N 3.13Å; N487-H693 VanDerWaalsContact CG-ND1 3.32Å; N487-H693 PolarHBondContact ND2-CE1 3.32Å; N487-H693 PolarHBondContact ND2-ND1 3.48Å; N487-H693 PolarHBondContact OD1-ND1 3.03Å; H693-D695 PolarHBondContact O-N 3.01Å
694I81.5Confident85.9Confident19 Ų1947.3 Ų47.310%0.09724%0.238CC..  trans-80.6121.7-178.5-63.3170.3000109.8F259 E486 A490 L696 M702F259-I694 HydrophobicContact CE1-CD1 3.92Å; F259-I694 HydrophobicContact CZ-CD1 4.23Å; E486-I694 HydrophobicContact CB-CD1 4.19Å; E486-I694 HydrophobicContact CB-CG1 4.36Å; E486-I694 HydrophobicContact CG-CD1 4.25Å; A490-I694 HydrophobicContact CB-CG1 4.3Å; I694-L696 HydrophobicContact CG2-CD2 3.88Å; I694-L696 HydrophobicContact CG2-CG 4.36Å; I694-L696 PolarHBondContact O-N 2.9Å; I694-M702 HydrophobicContact CD1-CE 4.07Å; I694-M702 HydrophobicContact CG1-CE 4.33Å; I694-M702 HydrophobicContact CG2-CB 3.96Å; I694-M702 HydrophobicContact CG2-CE 4.41Å
695D81.6Confident85.3Confident67 Ų6747.4 Ų47.436%0.35824%0.238SC..  trans-8390.6171.3-173-5.4000109.7H693 K697 K698 N699H693-D695 PolarHBondContact O-N 3.01Å; D695-K697 PolarHBondContact O-N 3.38Å; D695-K697 WeakPolarHBondContact OD1-CB 3.42Å; D695-K697 PolarHBondContact OD1-N 3.27Å; D695-K697 VanDerWaalsContact OD1-N 3.09Å; D695-K698 HydrophobicContact CB-CB 4.4Å; D695-K698 HydrophobicContact CB-CD 4.43Å; D695-K698 PolarHBondContact O-N 3.41Å; D695-K698 VanDerWaalsContact OD2-CD 3.28Å; D695-K698 WeakPolarHBondContact OD2-CD 3.31Å; D695-K698 VanDerWaalsContact OD2-CE 3.24Å; D695-K698 WeakPolarHBondContact OD2-CE 3.24Å; D695-K698 WeakPolarHBondContact OD2-CG 3.26Å; D695-K698 IonicContact OD2-NZ 2.63Å; D695-N699 PolarHBondContact O-N 2.85Å; D695-N699 PolarHBondContact O-ND2 2.83Å
696L83.9Confident85Confident18 Ų1847.3 Ų47.39%0.09424%0.239CC..THydrogen-bonded Turntrans-62.9-17.4178.3-68.4178.9000113.4I694 K698 N699 P700 M702 L703 L724 D725I694-L696 HydrophobicContact CG2-CD2 3.88Å; I694-L696 HydrophobicContact CG2-CG 4.36Å; I694-L696 PolarHBondContact O-N 2.9Å; L696-K698 VanDerWaalsContact C-N 3.28Å; L696-N699 CarbonylContact O-C 3.51Å; L696-P700 VanDerWaalsContact O-CA 3.24Å; L696-P700 WeakPolarHBondContact O-CA 3.36Å; L696-M702 WeakPolarHBondContact CD2-O 3.48Å; L696-L703 HydrophobicContact CD1-CD1 3.89Å; L696-L703 HydrophobicContact CD2-CD1 4.44Å; L696-L724 HydrophobicContact CD1-CB 4.34Å; L696-D725 HydrophobicContact CD1-CB 4.14Å
697K83.8Confident84.8Confident174 Ų17447.7 Ų47.776%0.75724%0.243SC*.THydrogen-bonded Turntrans-71.1-29.9172.8-63.8-174.9177.9-176.20111.7D695D695-K697 PolarHBondContact O-N 3.38Å; D695-K697 WeakPolarHBondContact OD1-CB 3.42Å; D695-K697 PolarHBondContact OD1-N 3.27Å; D695-K697 VanDerWaalsContact OD1-N 3.09Å
698K86Confident84.8Confident163 Ų16346.9 Ų46.971%0.70924%0.237SC*.THydrogen-bonded Turntrans-91.4-30.8177.9-67.7-179.3-174.2175.50112.7D695 L696D695-K698 HydrophobicContact CB-CB 4.4Å; D695-K698 HydrophobicContact CB-CD 4.43Å; D695-K698 PolarHBondContact O-N 3.41Å; D695-K698 VanDerWaalsContact OD2-CD 3.28Å; D695-K698 WeakPolarHBondContact OD2-CD 3.31Å; D695-K698 VanDerWaalsContact OD2-CE 3.24Å; D695-K698 WeakPolarHBondContact OD2-CE 3.24Å; D695-K698 WeakPolarHBondContact OD2-CG 3.26Å; D695-K698 IonicContact OD2-NZ 2.63Å; L696-K698 VanDerWaalsContact C-N 3.28Å
699N86.7Confident85Confident36 Ų3646.2 Ų46.219%0.19323%0.234CC..  trans-131.970.1-177.2-45.3-89.8000109.6D695 L696 E701 M702D695-N699 PolarHBondContact O-N 2.85Å; D695-N699 PolarHBondContact O-ND2 2.83Å; L696-N699 CarbonylContact O-C 3.51Å; N699-E701 WeakPolarHBondContact CA-OE2 3.31Å; N699-E701 PolarHBondContact O-N 3.48Å; N699-M702 HydrophobicContact CB-CB 4.25Å; N699-M702 HydrophobicContact CB-CG 3.91Å; N699-M702 HydrophobicContact CB-SD 3.5Å; N699-M702 VanDerWaalsContact CB-SD 3.5Å; N699-M702 PolarHBondContact O-N 2.93Å
700P86.5Confident85.6Confident90 Ų9045.6 Ų45.658%0.58423%0.231SC*.THydrogen-bonded Turntrans-62.3-24.3-175.125.7-35.6000113.9L696 M702L696-P700 VanDerWaalsContact O-CA 3.24Å; L696-P700 WeakPolarHBondContact O-CA 3.36Å; P700-M702 VanDerWaalsContact C-N 3.3Å; P700-M702 PolarHBondContact O-N 3.49Å
701E85.4Confident86.5Confident65 Ų6543.2 Ų43.230%0.30422%0.215SC..THydrogen-bonded Turntrans-72.3-20.2177.872.7-78-171.700113.7L262 Y493 N699 L703L262-E701 HydrophobicContact CD1-CG 4.43Å; L262-E701 HydrophobicContact CD2-CG 4.23Å; Y493-E701 HydrophobicContact CE1-CG 4.4Å; Y493-E701 WeakPolarHBondContact CE1-OE1 3.44Å; Y493-E701 PolarHBondContact OH-OE1 3.34Å; N699-E701 WeakPolarHBondContact CA-OE2 3.31Å; N699-E701 PolarHBondContact O-N 3.48Å; E701-L703 PolarHBondContact O-N 2.81Å
702M88.7Confident87.3Confident1 Ų145.1 Ų45.11%0.00523%0.23CC..  trans-83.837.9-178.5-65.1178.969.600112.6F259 L262 A490 Y493 L494 I694 L696 N699 P700 S704F259-M702 HydrophobicContact CD1-CB 4.15Å; F259-M702 WeakPolarHBondContact CD1-O 3.44Å; F259-M702 HydrophobicContact CE1-CB 3.63Å; F259-M702 HydrophobicContact CE1-CE 4.25Å; F259-M702 HydrophobicContact CE1-CG 4.29Å; F259-M702 WeakPolarHBondContact CE1-O 3.39Å; F259-M702 HydrophobicContact CE2-CE 4.28Å; F259-M702 HydrophobicContact CE2-CG 4.46Å; F259-M702 HydrophobicContact CZ-CB 3.88Å; F259-M702 HydrophobicContact CZ-CE 3.52Å; F259-M702 HydrophobicContact CZ-CG 4.05Å; L262-M702 HydrophobicContact CD2-CG 4.16Å; A490-M702 HydrophobicContact CB-CE 3.73Å; Y493-M702 HydrophobicContact CD1-CE 4.39Å; Y493-M702 HydrophobicContact CD1-CG 4.05Å; Y493-M702 HydrophobicContact CD1-SD 3.78Å; Y493-M702 HydrophobicContact CE1-CG 4.23Å; Y493-M702 HydrophobicContact CE1-SD 4.26Å; L494-M702 HydrophobicContact CD1-CE 4.24Å; L494-M702 HydrophobicContact CD1-SD 4.11Å; L494-M702 HydrophobicContact CD2-SD 4.07Å; L494-M702 HydrophobicContact CG-CE 4.35Å; L494-M702 HydrophobicContact CG-SD 4.13Å; I694-M702 HydrophobicContact CD1-CE 4.07Å; I694-M702 HydrophobicContact CG1-CE 4.33Å; I694-M702 HydrophobicContact CG2-CB 3.96Å; I694-M702 HydrophobicContact CG2-CE 4.41Å; L696-M702 WeakPolarHBondContact CD2-O 3.48Å; N699-M702 HydrophobicContact CB-CB 4.25Å; N699-M702 HydrophobicContact CB-CG 3.91Å; N699-M702 HydrophobicContact CB-SD 3.5Å; N699-M702 VanDerWaalsContact CB-SD 3.5Å; N699-M702 PolarHBondContact O-N 2.93Å; P700-M702 VanDerWaalsContact C-N 3.3Å; P700-M702 PolarHBondContact O-N 3.49Å; M702-S704 PolarHBondContact O-N 3.15Å
703L88Confident88.4Confident13 Ų1342.7 Ų42.77%0.06822%0.22CC..  trans-73.9107.3178.6-162.679.3000109.5F259 L260 Y261 L696 E701 L724F259-L703 CarbonylContact C-O 3.46Å; F259-L703 VanDerWaalsContact CA-O 3.28Å; F259-L703 WeakPolarHBondContact CA-O 3.13Å; L260-L703 HydrophobicContact CB-CD2 4.49Å; L260-L703 HydrophobicContact CD2-CD2 3.93Å; L260-L703 PolarHBondContact N-O 2.91Å; Y261-L703 HydrophobicContact CE2-CD2 4.02Å; L696-L703 HydrophobicContact CD1-CD1 3.89Å; L696-L703 HydrophobicContact CD2-CD1 4.44Å; E701-L703 PolarHBondContact O-N 2.81Å; L703-L724 HydrophobicContact CD1-CB 3.78Å; L703-L724 HydrophobicContact CD1-CD1 3.8Å; L703-L724 HydrophobicContact CD1-CD2 4.11Å; L703-L724 HydrophobicContact CD1-CG 4.1Å; L703-L724 HydrophobicContact CD2-CD1 4Å; L703-L724 HydrophobicContact CG-CD1 3.9Å; L703-L724 HydrophobicContact CG-CD2 4.3Å
704S85.5Confident89.4Confident7 Ų743.8 Ų43.85%0.04923%0.229CC..BIsolated β-bridgetrans-85.7135.5174.6173.30000110.2M702 G706 L724M702-S704 PolarHBondContact O-N 3.15Å; S704-G706 PolarHBondContact O-N 3.44Å; S704-G706 VanDerWaalsContact O-N 3.16Å; S704-G706 PolarHBondContact OG-N 3.3Å; S704-L724 WeakPolarHBondContact O-CD2 3.49Å
705S86.6Confident90.1Very high1 Ų145.2 Ų45.21%0.00724%0.237CC..  trans-71.2-2.8176.4-65.20000114D258 L260 H730 H732D258-S705 PolarHBondContact O-N 2.92Å; L260-S705 WeakPolarHBondContact CD1-OG 3.28Å; S705-H730 VanDerWaalsContact CB-CE1 3.42Å; S705-H730 WeakPolarHBondContact CB-CE1 3.29Å; S705-H730 WeakPolarHBondContact CB-ND1 3.49Å; S705-H730 PolarHBondContact OG-CE1 2.81Å; S705-H730 VanDerWaalsContact OG-CE1 3.24Å; S705-H730 PolarHBondContact OG-ND1 3.47Å; S705-H732 PolarHBondContact O-NE2 2.86Å
706G91.8Very high90.9Very high8 Ų842 Ų428%0.08222%0.22CC..  trans72.1-137.8-175.400000111.3A256 M257 S704A256-G706 WeakPolarHBondContact CA-O 3.4Å; M257-G706 PolarHBondContact N-O 3.43Å; S704-G706 PolarHBondContact O-N 3.44Å; S704-G706 VanDerWaalsContact O-N 3.16Å; S704-G706 PolarHBondContact OG-N 3.3Å
707G94.3Very high91.6Very high8 Ų841.2 Ų41.28%0.08222%0.215CC..  trans-165.8171.6-173.300000112.4F255 S720 H732F255-G707 CarbonylContact O-C 3.59Å; F255-G707 WeakPolarHBondContact O-CA 3.48Å; G707-S720 WeakPolarHBondContact O-CB 3.38Å; G707-S720 PolarHBondContact O-OG 3.31Å; G707-S720 VanDerWaalsContact O-OG 3.11Å; G707-H732 PolarHBondContact O-CD2 3.48Å; G707-H732 VanDerWaalsContact O-CD2 3.25Å
708G96.3Very high92.3Very high2 Ų233 Ų332%0.02118%0.179CC..  trans-148-175.6-176.100000113.3Y254 F255Y254-G708 WeakPolarHBondContact CA-O 3.44Å; Y254-G708 WeakPolarHBondContact CB-O 3.37Å; F255-G708 WeakPolarHBondContact CD1-O 3.45Å; F255-G708 WeakPolarHBondContact CE1-O 3.5Å; F255-G708 PolarHBondContact N-O 3.12Å; F255-G708 PolarHBondContact O-N 3.06Å
709F97.9Very high92.9Very high36 Ų3625.2 Ų25.216%0.15815%0.146CC..BIsolated β-bridgetrans-149.2163.5-178.352.1-83.1000109.5S687 S734S687-F709 VanDerWaalsContact OG-CE1 3.24Å; S687-F709 WeakPolarHBondContact OG-CE1 3.36Å; F709-S734 WeakPolarHBondContact O-CB 3.27Å; F709-S734 PolarHBondContact O-OG 2.89Å
710G96.9Very high93.4Very high3 Ų323.6 Ų23.63%0.03114%0.137CC..  trans-71.5168.1174.500000113S734G710-S734 VanDerWaalsContact C-OG 3.23Å; G710-S734 WeakPolarHBondContact CA-OG 3.42Å
711P95.3Very high93.9Very high4 Ų419.4 Ų19.43%0.02611%0.11CC..  trans-66.9149.217631.4-37000110.8S734 K736P711-S734 WeakPolarHBondContact CD-OG 3.41Å; P711-K736 HydrophobicContact CG-CD 3.75Å; P711-K736 HydrophobicContact CG-CG 3.93Å
712V92.3Very high94.3Very high81 Ų8116.6 Ų16.649%0.49110%0.097SC..SBendtrans-96-6.4179.2-54.60000113.4W682 S685W682-V712 HydrophobicContact CB-CG2 3.81Å; W682-V712 WeakPolarHBondContact O-CG2 3.37Å; S685-V712 VanDerWaalsContact CB-CG2 3.42Å
713A94.3Very high94.6Very high9 Ų917.4 Ų17.47%0.07410%0.101CC..SBendtrans-135.1140174.900000107.9P681 D715 G716P681-A713 HydrophobicContact CB-CB 4.07Å; A713-D715 PolarHBondContact O-N 3.4Å; A713-G716 PolarHBondContact O-N 3.05Å
714D94.9Very high94.6Very high114 Ų11416.9 Ų16.961%0.6110%0.098SC*.THydrogen-bonded Turntrans-64.4-27.3-178.5-63.5-30.3000112.1C739D714-C739 VanDerWaalsContact O-CB 3.3Å; D714-C739 WeakPolarHBondContact O-CB 3.49Å
715D96.4Very high94.7Very high50 Ų5018.8 Ų18.827%0.26711%0.108SC..THydrogen-bonded Turntrans-104.631.8177.369.3-20.8000112.9R683 A713R683-D715 IonicContact CZ-OD1 2.68Å; R683-D715 IonicContact CZ-OD2 3.03Å; R683-D715 VanDerWaalsContact NE-CG 3.33Å; R683-D715 IonicContact NE-OD1 3.23Å; R683-D715 PolarHBondContact NE-OD1 3.21Å; R683-D715 IonicContact NE-OD2 2.79Å; R683-D715 PolarHBondContact NE-OD2 2.95Å; R683-D715 IonicContact NH2-OD1 2.85Å; R683-D715 IonicContact NH2-OD2 3.47Å; R683-D715 PolarHBondContact NH2-OD2 3.14Å; A713-D715 PolarHBondContact O-N 3.4Å
716G97.2Very high94.9Very high0 Ų021.8 Ų21.80%012%0.122CC..SBendtrans-144-176.2-175.200000115.5R683 A713R683-G716 CarbonylContact O-C 3.46Å; R683-G716 WeakPolarHBondContact O-CA 3.28Å; A713-G716 PolarHBondContact O-N 3.05Å
717Y98.6Very high94.9Very high1 Ų126.4 Ų26.40%0.00415%0.145CC..EExtended strand (participates in β ladder)trans-116.1141.4-178.1-65-74.4000112.3D581 M582 R683 S685 V733 S734 T742 D743 F747D581-Y717 PolarHBondContact OD2-OH 3.23Å; M582-Y717 HydrophobicContact CE-CD2 4.27Å; M582-Y717 HydrophobicContact CE-CE2 3.46Å; M582-Y717 VanDerWaalsContact CE-CE2 3.46Å; R683-Y717 PolarHBondContact O-N 3.45Å; S685-Y717 PolarHBondContact N-O 2.98Å; Y717-V733 HydrophobicContact CD1-CG1 4.15Å; Y717-S734 CarbonylContact C-O 3.43Å; Y717-S734 VanDerWaalsContact CA-O 3.27Å; Y717-S734 WeakPolarHBondContact CA-O 3.49Å; Y717-T742 HydrophobicContact CD2-CG2 4.47Å; Y717-T742 HydrophobicContact CE1-CG2 4.16Å; Y717-T742 HydrophobicContact CE2-CG2 4.08Å; Y717-T742 WeakPolarHBondContact OH-CA 3.28Å; Y717-D743 PolarHBondContact OH-N 2.85Å; Y717-D743 PolarHBondContact OH-O 3.26Å; Y717-F747 HydrophobicContact CD1-CB 4.32Å; Y717-F747 AromaticContact CD1-CD1 3.56Å; Y717-F747 HydrophobicContact CD1-CD1 3.56Å; Y717-F747 HydrophobicContact CD1-CE1 4.23Å; Y717-F747 HydrophobicContact CD1-CG 4.22Å; Y717-F747 AromaticContact CD2-CD1 3.78Å; Y717-F747 HydrophobicContact CD2-CD1 3.78Å; Y717-F747 AromaticContact CD2-CE1 3.87Å; Y717-F747 HydrophobicContact CD2-CE1 3.87Å; Y717-F747 HydrophobicContact CD2-CG 4.25Å; Y717-F747 HydrophobicContact CD2-CZ 4.43Å; Y717-F747 HydrophobicContact CE1-CB 3.72Å; Y717-F747 AromaticContact CE1-CD1 3.83Å; Y717-F747 HydrophobicContact CE1-CD1 3.83Å; Y717-F747 HydrophobicContact CE1-CG 4.01Å; Y717-F747 HydrophobicContact CE2-CB 4.3Å; Y717-F747 AromaticContact CE2-CD1 3.99Å; Y717-F747 HydrophobicContact CE2-CD1 3.99Å; Y717-F747 HydrophobicContact CE2-CD2 4.38Å; Y717-F747 HydrophobicContact CE2-CE1 4.41Å; Y717-F747 AromaticContact CE2-CG 3.98Å; Y717-F747 HydrophobicContact CE2-CG 3.98Å; Y717-F747 AromaticContact CG-CD1 3.54Å; Y717-F747 HydrophobicContact CG-CD1 3.54Å; Y717-F747 AromaticContact CG-CE1 3.75Å; Y717-F747 HydrophobicContact CG-CE1 3.75Å; Y717-F747 HydrophobicContact CG-CG 4.34Å; Y717-F747 AromaticContact CZ-CG 3.87Å
718G98.3Very high94.8Very high0 Ų026.4 Ų26.40%014%0.143CC..EExtended strand (participates in β ladder)trans-99129.2158.900000110S685 V733 S734S685-G718 CarbonylContact O-C 3.57Å; S685-G718 WeakPolarHBondContact O-CA 3.39Å; G718-V733 CarbonylContact O-C 3.46Å; G718-V733 WeakPolarHBondContact O-CA 3.4Å; G718-S734 PolarHBondContact N-O 3.46Å; G718-S734 PolarHBondContact O-N 3.3Å; G718-S734 PolarHBondContact O-OG 3.44Å
719V98.5Very high94.8Very high0 Ų026.3 Ų26.30%014%0.142CC..EExtended strand (participates in β ladder)trans-131.7113.5178.1-1730000110.9L574 L684 S685 T686 S687 F731 H732 V733 F747L574-V719 HydrophobicContact CD1-CG1 4.2Å; L574-V719 HydrophobicContact CD2-CG1 4.06Å; L684-V719 HydrophobicContact CD1-CG2 3.8Å; S685-V719 PolarHBondContact O-N 3.45Å; T686-V719 CarbonylContact C-O 3.56Å; T686-V719 WeakPolarHBondContact CA-O 3.31Å; T686-V719 HydrophobicContact CG2-CB 4.29Å; S687-V719 PolarHBondContact N-O 2.91Å; V719-F731 HydrophobicContact CG1-CD1 4.3Å; V719-H732 CarbonylContact C-O 3.57Å; V719-H732 VanDerWaalsContact CA-O 3.3Å; V719-H732 WeakPolarHBondContact CA-O 3.38Å; V719-V733 HydrophobicContact CG1-CG2 4.49Å; V719-V733 HydrophobicContact CG2-CG1 4.49Å; V719-V733 HydrophobicContact CG2-CG2 4.49Å; V719-F747 HydrophobicContact CG2-CD1 4.44Å; V719-F747 HydrophobicContact CG2-CE1 3.67Å
720S97.6Very high94.7Very high3 Ų324.6 Ų24.62%0.02114%0.135CC..EExtended strand (participates in β ladder)trans-105.4146.2165.2-160.90000110.9S687 G707 F731 H732S687-S720 WeakPolarHBondContact O-CA 3.35Å; S687-S720 PolarHBondContact O-OG 3.43Å; G707-S720 WeakPolarHBondContact O-CB 3.38Å; G707-S720 PolarHBondContact O-OG 3.31Å; G707-S720 VanDerWaalsContact O-OG 3.11Å; S720-F731 CarbonylContact O-C 3.52Å; S720-F731 WeakPolarHBondContact O-CA 3.45Å; S720-H732 PolarHBondContact N-O 3.16Å; S720-H732 PolarHBondContact O-N 2.97Å
721Y97.3Very high94.7Very high1 Ų124.5 Ų24.50%0.00413%0.133CC..EExtended strand (participates in β ladder)trans-140.8148.7172.957.4-87.5000112.3D567 V570 Q571 L574 E590 S687 Q688 T689 I723 H730 F731D567-Y721 PolarHBondContact OD1-OH 2.84Å; V570-Y721 HydrophobicContact CB-CD2 4.48Å; V570-Y721 HydrophobicContact CB-CE2 4.14Å; V570-Y721 HydrophobicContact CG1-CD1 3.88Å; V570-Y721 HydrophobicContact CG1-CD2 3.89Å; V570-Y721 HydrophobicContact CG1-CE1 3.81Å; V570-Y721 HydrophobicContact CG1-CE2 3.82Å; V570-Y721 HydrophobicContact CG1-CG 3.93Å; Q571-Y721 PolarHBondContact NE2-OH 3.33Å; L574-Y721 HydrophobicContact CD1-CD1 4.49Å; L574-Y721 HydrophobicContact CD1-CE1 4.19Å; E590-Y721 PolarHBondContact OE1-OH 3.46Å; S687-Y721 PolarHBondContact O-N 2.72Å; S687-Y721 VanDerWaalsContact O-N 3.1Å; Q688-Y721 WeakPolarHBondContact CA-O 3.46Å; Q688-Y721 HydrophobicContact CB-CD2 4.26Å; Q688-Y721 HydrophobicContact CB-CE2 3.63Å; Q688-Y721 HydrophobicContact CG-CD2 4.08Å; Q688-Y721 HydrophobicContact CG-CE2 3.69Å; T689-Y721 PolarHBondContact N-O 2.91Å; Y721-I723 HydrophobicContact CD2-CG1 4.33Å; Y721-H730 VanDerWaalsContact CA-O 3.22Å; Y721-H730 WeakPolarHBondContact CA-O 3.27Å; Y721-F731 HydrophobicContact CD1-CE1 4.43Å; Y721-F731 HydrophobicContact CG-CD1 4.49Å; Y721-F731 HydrophobicContact CG-CE1 4.18Å
722I94.5Very high94.9Very high7 Ų724.4 Ų24.44%0.03613%0.133CC..EExtended strand (participates in β ladder)trans-123.8125.3172.1-179.3161.8000109.1T689 Q691 L724 I729 H730T689-I722 VanDerWaalsContact O-CG1 3.28Å; T689-I722 WeakPolarHBondContact O-CG1 3.38Å; Q691-I722 HydrophobicContact CB-CD1 4.35Å; I722-L724 HydrophobicContact CD1-CD2 4.17Å; I722-L724 HydrophobicContact CG1-CD2 3.95Å; I722-L724 HydrophobicContact CG2-CD2 3.86Å; I722-L724 HydrophobicContact CG2-CG 4.28Å; I722-L724 PolarHBondContact O-N 2.83Å; I722-I729 WeakPolarHBondContact O-CA 3.26Å; I722-I729 WeakPolarHBondContact O-CG2 3.42Å; I722-H730 HydrophobicContact CG2-CB 3.67Å; I722-H730 PolarHBondContact N-O 2.9Å; I722-H730 PolarHBondContact O-N 3.49Å
723I93.4Very high95.2Very high17 Ų1720.6 Ų20.69%0.08711%0.11CC..EExtended strand (participates in β ladder)trans-88.199175.1-56.3-175.5000107.4K556 P566 Y721 I729K556-I723 HydrophobicContact CB-CG2 3.7Å; K556-I723 HydrophobicContact CD-CG2 3.96Å; K556-I723 HydrophobicContact CG-CG2 4.39Å; P566-I723 HydrophobicContact CB-CD1 3.6Å; Y721-I723 HydrophobicContact CD2-CG1 4.33Å; I723-I729 HydrophobicContact CG1-CD1 4.47Å; I723-I729 HydrophobicContact CG1-CG1 4.46Å; I723-I729 HydrophobicContact CG1-CG2 4.41Å; I723-I729 HydrophobicContact CG2-CG1 4.36Å
724L88.5Confident95.4Very high2 Ų220.1 Ų20.11%0.0111%0.106CC..  trans-72.1-70.9-169.7-61.1165.6000110.4L550 K556 Q691 L696 L703 S704 I722 S728 H730L550-L724 HydrophobicContact CD1-CD1 3.65Å; K556-L724 PolarHBondContact NZ-O 2.94Å; K556-L724 VanDerWaalsContact NZ-O 3.11Å; Q691-L724 PolarHBondContact OE1-O 3.23Å; L696-L724 HydrophobicContact CD1-CB 4.34Å; L703-L724 HydrophobicContact CD1-CB 3.78Å; L703-L724 HydrophobicContact CD1-CD1 3.8Å; L703-L724 HydrophobicContact CD1-CD2 4.11Å; L703-L724 HydrophobicContact CD1-CG 4.1Å; L703-L724 HydrophobicContact CD2-CD1 4Å; L703-L724 HydrophobicContact CG-CD1 3.9Å; L703-L724 HydrophobicContact CG-CD2 4.3Å; S704-L724 WeakPolarHBondContact O-CD2 3.49Å; I722-L724 HydrophobicContact CD1-CD2 4.17Å; I722-L724 HydrophobicContact CG1-CD2 3.95Å; I722-L724 HydrophobicContact CG2-CD2 3.86Å; I722-L724 HydrophobicContact CG2-CG 4.28Å; I722-L724 PolarHBondContact O-N 2.83Å; L724-S728 PolarHBondContact N-O 3.33Å; L724-H730 HydrophobicContact CD1-CB 4.04Å
725D88.2Confident95.5Very high47 Ų4714.7 Ų14.725%0.2518%0.077SC..SBendtrans-135.8-158.3-172.170.66000112.2K556 L696 N727 S728K556-D725 WeakPolarHBondContact CD-O 3.44Å; K556-D725 VanDerWaalsContact CG-O 3.25Å; K556-D725 WeakPolarHBondContact CG-O 3.25Å; K556-D725 PolarHBondContact N-O 3.3Å; L696-D725 HydrophobicContact CD1-CB 4.14Å; D725-N727 PolarHBondContact O-N 3.44Å; D725-N727 WeakPolarHBondContact OD1-CA 3.44Å; D725-N727 PolarHBondContact OD1-N 3.29Å; D725-S728 PolarHBondContact OD1-N 2.91Å; D725-S728 PolarHBondContact OD1-OG 3.33Å
726E90.4Very high95.6Very high65 Ų6512.5 Ų12.530%0.3047%0.065SC..SBendtrans-69.5-20.5179.7-58.7-59142.900112.7G555 K556 G557G555-E726 CarbonylContact C-O 3.51Å; G555-E726 VanDerWaalsContact CA-O 3.23Å; G555-E726 WeakPolarHBondContact CA-O 3.36Å; G555-E726 PolarHBondContact N-O 3.17Å; G555-E726 VanDerWaalsContact N-O 3.14Å; K556-E726 VanDerWaalsContact CE-OE1 3.31Å; K556-E726 WeakPolarHBondContact CE-OE1 3.09Å; G557-E726 WeakPolarHBondContact CA-OE2 3.16Å; G557-E726 PolarHBondContact N-O 2.88Å; G557-E726 PolarHBondContact N-OE2 2.94Å
727N92.4Very high95.6Very high105 Ų10517.4 Ų17.456%0.5619%0.09SC*.SBendtrans-125-9.8-166-59.7-34000114.4D552 F554 G555 D725D552-N727 CarbonylContact C-O 3.56Å; F554-N727 CarbonylContact C-O 3.28Å; F554-N727 VanDerWaalsContact CA-O 3.26Å; F554-N727 WeakPolarHBondContact CA-O 3.29Å; F554-N727 PolarHBondContact N-O 3.17Å; G555-N727 VanDerWaalsContact N-CA 3.28Å; G555-N727 PolarHBondContact N-O 3.36Å; D725-N727 PolarHBondContact O-N 3.44Å; D725-N727 WeakPolarHBondContact OD1-CA 3.44Å; D725-N727 PolarHBondContact OD1-N 3.29Å
728S92.6Very high95.6Very high8 Ų821.5 Ų21.56%0.05612%0.119CC..  trans-141.2150.7-172.962.40000114.9F551 L724 D725F551-S728 CarbonylContact O-C 3.54Å; F551-S728 VanDerWaalsContact O-CA 3.24Å; F551-S728 WeakPolarHBondContact O-CA 3.47Å; L724-S728 PolarHBondContact N-O 3.33Å; D725-S728 PolarHBondContact OD1-N 2.91Å; D725-S728 PolarHBondContact OD1-OG 3.33Å
729I95.6Very high95.5Very high0 Ų022.4 Ų22.40%013%0.125CC..EExtended strand (participates in β ladder)trans-139.1134.6174.8-55.2177.5000107.3F551 I559 V570 I722 I723 F731 M755F551-I729 WeakPolarHBondContact CA-O 3.2Å; F551-I729 WeakPolarHBondContact CB-O 3.25Å; F551-I729 PolarHBondContact N-O 2.83Å; F551-I729 PolarHBondContact O-N 3.32Å; I559-I729 HydrophobicContact CD1-CD1 4.14Å; V570-I729 HydrophobicContact CG2-CD1 3.99Å; I722-I729 WeakPolarHBondContact O-CA 3.26Å; I722-I729 WeakPolarHBondContact O-CG2 3.42Å; I723-I729 HydrophobicContact CG1-CD1 4.47Å; I723-I729 HydrophobicContact CG1-CG1 4.46Å; I723-I729 HydrophobicContact CG1-CG2 4.41Å; I723-I729 HydrophobicContact CG2-CG1 4.36Å; I729-F731 HydrophobicContact CB-CE2 3.96Å; I729-F731 HydrophobicContact CG2-CD2 4.09Å; I729-F731 HydrophobicContact CG2-CE1 4.48Å; I729-F731 HydrophobicContact CG2-CE2 3.49Å; I729-F731 VanDerWaalsContact CG2-CE2 3.49Å; I729-F731 HydrophobicContact CG2-CZ 3.72Å; I729-M755 HydrophobicContact CD1-CE 3.76Å
730H95.6Very high95.4Very high0 Ų028 Ų280%016%0.164CC..EExtended strand (participates in β ladder)trans-103.8134.6174.2-156.5127.3000109.5S548 F549 L550 S705 Y721 I722 L724 H732S548-H730 PolarHBondContact OG-NE2 2.8Å; F549-H730 PolarHBondContact O-CD2 3.15Å; F549-H730 VanDerWaalsContact O-CD2 3.26Å; L550-H730 HydrophobicContact CD1-CB 4.43Å; S705-H730 VanDerWaalsContact CB-CE1 3.42Å; S705-H730 WeakPolarHBondContact CB-CE1 3.29Å; S705-H730 WeakPolarHBondContact CB-ND1 3.49Å; S705-H730 PolarHBondContact OG-CE1 2.81Å; S705-H730 VanDerWaalsContact OG-CE1 3.24Å; S705-H730 PolarHBondContact OG-ND1 3.47Å; Y721-H730 VanDerWaalsContact CA-O 3.22Å; Y721-H730 WeakPolarHBondContact CA-O 3.27Å; I722-H730 HydrophobicContact CG2-CB 3.67Å; I722-H730 PolarHBondContact N-O 2.9Å; I722-H730 PolarHBondContact O-N 3.49Å; L724-H730 HydrophobicContact CD1-CB 4.04Å; H730-H732 AromaticContact CD2-CE1 3.92Å; H730-H732 AromaticContact CD2-NE2 3.56Å; H730-H732 AromaticContact NE2-CE1 3.92Å; H730-H732 AromaticContact NE2-NE2 4Å
731F97.9Very high95.3Very high0 Ų032.3 Ų32.30%018%0.184CC..EExtended strand (participates in β ladder)trans-115144.7177.5-69.9-90.1000111.7S548 F549 F551 V570 V719 S720 Y721 I729 I751S548-F731 WeakPolarHBondContact CA-O 3.47Å; S548-F731 PolarHBondContact OG-O 2.9Å; F549-F731 HydrophobicContact CD1-CB 4.24Å; F549-F731 HydrophobicContact CE1-CB 3.72Å; F549-F731 HydrophobicContact CE1-CG 4.49Å; F549-F731 HydrophobicContact CE2-CB 4.07Å; F549-F731 AromaticContact CE2-CD2 3.78Å; F549-F731 HydrophobicContact CE2-CD2 3.78Å; F549-F731 HydrophobicContact CE2-CG 4.2Å; F549-F731 HydrophobicContact CZ-CB 3.63Å; F549-F731 AromaticContact CZ-CD2 3.96Å; F549-F731 HydrophobicContact CZ-CD2 3.96Å; F549-F731 AromaticContact CZ-CG 3.92Å; F549-F731 HydrophobicContact CZ-CG 3.92Å; F549-F731 PolarHBondContact N-O 3.46Å; F549-F731 PolarHBondContact O-N 3.05Å; F551-F731 HydrophobicContact CB-CD2 4.21Å; F551-F731 HydrophobicContact CB-CE2 4.04Å; V570-F731 HydrophobicContact CG1-CE1 3.72Å; V570-F731 HydrophobicContact CG1-CZ 3.98Å; V570-F731 HydrophobicContact CG2-CZ 4.45Å; V719-F731 HydrophobicContact CG1-CD1 4.3Å; S720-F731 CarbonylContact O-C 3.52Å; S720-F731 WeakPolarHBondContact O-CA 3.45Å; Y721-F731 HydrophobicContact CD1-CE1 4.43Å; Y721-F731 HydrophobicContact CG-CD1 4.49Å; Y721-F731 HydrophobicContact CG-CE1 4.18Å; I729-F731 HydrophobicContact CB-CE2 3.96Å; I729-F731 HydrophobicContact CG2-CD2 4.09Å; I729-F731 HydrophobicContact CG2-CE1 4.48Å; I729-F731 HydrophobicContact CG2-CE2 3.49Å; I729-F731 VanDerWaalsContact CG2-CE2 3.49Å; I729-F731 HydrophobicContact CG2-CZ 3.72Å; F731-I751 HydrophobicContact CD1-CG2 4.23Å; F731-I751 HydrophobicContact CE1-CG2 3.97Å; F731-I751 HydrophobicContact CE2-CG2 4.37Å; F731-I751 HydrophobicContact CZ-CG2 4.05Å
732H98Very high95.3Very high3 Ų332.8 Ų32.81%0.01419%0.187CC..EExtended strand (participates in β ladder)trans-126.3112.6170.4-59.5-93.4000107.8F255 S548 S705 G707 V719 S720 H730F255-H732 AromaticContact CE2-ND1 3.96Å; F255-H732 AromaticContact CZ-ND1 3.82Å; S548-H732 PolarHBondContact OG-CE1 3.5Å; S548-H732 PolarHBondContact OG-ND1 3.14Å; S705-H732 PolarHBondContact O-NE2 2.86Å; G707-H732 PolarHBondContact O-CD2 3.48Å; G707-H732 VanDerWaalsContact O-CD2 3.25Å; V719-H732 CarbonylContact C-O 3.57Å; V719-H732 VanDerWaalsContact CA-O 3.3Å; V719-H732 WeakPolarHBondContact CA-O 3.38Å; S720-H732 PolarHBondContact N-O 3.16Å; S720-H732 PolarHBondContact O-N 2.97Å; H730-H732 AromaticContact CD2-CE1 3.92Å; H730-H732 AromaticContact CD2-NE2 3.56Å; H730-H732 AromaticContact NE2-CE1 3.92Å; H730-H732 AromaticContact NE2-NE2 4Å
733V98.6Very high95.5Very high0 Ų035.4 Ų35.40%020%0.201CC..EExtended strand (participates in β ladder)trans-109.7136.9179.7-175.70000108.7F546 H547 F549 Y717 G718 V719 F747 I751F546-V733 CarbonylContact C-O 3.37Å; F546-V733 WeakPolarHBondContact CA-O 3.48Å; H547-V733 HydrophobicContact CB-CB 4.43Å; H547-V733 PolarHBondContact N-O 3.08Å; H547-V733 PolarHBondContact O-N 3.29Å; F549-V733 HydrophobicContact CE1-CG2 4.19Å; Y717-V733 HydrophobicContact CD1-CG1 4.15Å; G718-V733 CarbonylContact O-C 3.46Å; G718-V733 WeakPolarHBondContact O-CA 3.4Å; V719-V733 HydrophobicContact CG1-CG2 4.49Å; V719-V733 HydrophobicContact CG2-CG1 4.49Å; V719-V733 HydrophobicContact CG2-CG2 4.49Å; V733-F747 HydrophobicContact CG1-CD1 3.71Å; V733-F747 HydrophobicContact CG1-CE1 4.48Å; V733-I751 HydrophobicContact CG2-CD1 3.85Å
734S98.6Very high95.7Very high0 Ų034.6 Ų34.60%020%0.197CC..EExtended strand (participates in β ladder)trans-135.8149.1174.463.40000111.7D545 F546 F709 G710 P711 Y717 G718D545-S734 VanDerWaalsContact O-CA 3.23Å; D545-S734 WeakPolarHBondContact O-CA 3.34Å; F546-S734 VanDerWaalsContact CE1-CB 3.48Å; F709-S734 WeakPolarHBondContact O-CB 3.27Å; F709-S734 PolarHBondContact O-OG 2.89Å; G710-S734 VanDerWaalsContact C-OG 3.23Å; G710-S734 WeakPolarHBondContact CA-OG 3.42Å; P711-S734 WeakPolarHBondContact CD-OG 3.41Å; Y717-S734 CarbonylContact C-O 3.43Å; Y717-S734 VanDerWaalsContact CA-O 3.27Å; Y717-S734 WeakPolarHBondContact CA-O 3.49Å; G718-S734 PolarHBondContact N-O 3.46Å; G718-S734 PolarHBondContact O-N 3.3Å; G718-S734 PolarHBondContact O-OG 3.44Å
735S98.5Very high96.2Very high0 Ų037.1 Ų37.10%021%0.209CC..EExtended strand (participates in β ladder)trans-154.5-176.1174.660.40000111D545 S744D545-S735 PolarHBondContact N-O 2.92Å; D545-S735 PolarHBondContact O-N 3.44Å; D545-S735 VanDerWaalsContact O-N 3.11Å; S735-S744 PolarHBondContact N-OG 3.3Å; S735-S744 PolarHBondContact OG-N 3.39Å; S735-S744 PolarHBondContact OG-OG 3.42Å
736K97.9Very high96.7Very high4 Ų439.2 Ų39.22%0.01721%0.213CC..EExtended strand (participates in β ladder)trans-104.8130.3175.8-62.5-50.6-147.5121.80111.4D543 V544 P711 S738 C739 T742D543-K736 CarbonylContact O-C 3.43Å; D543-K736 VanDerWaalsContact O-CA 3.3Å; D543-K736 WeakPolarHBondContact O-CA 3.43Å; D543-K736 WeakPolarHBondContact OD2-CD 3.38Å; D543-K736 IonicContact OD2-NZ 3.2Å; D543-K736 PolarHBondContact OD2-NZ 3.24Å; V544-K736 HydrophobicContact CG2-CD 4.2Å; P711-K736 HydrophobicContact CG-CD 3.75Å; P711-K736 HydrophobicContact CG-CG 3.93Å; K736-S738 PolarHBondContact O-N 3.48Å; K736-C739 HydrophobicContact CB-CB 4.48Å; K736-C739 PolarHBondContact O-N 3.28Å; K736-C739 VanDerWaalsContact O-N 3.16Å; K736-T742 PolarHBondContact O-OG1 2.56Å; K736-T742 VanDerWaalsContact O-OG1 3.14Å
737I97.8Very high97Very high102 Ų10236.1 Ų36.152%0.52320%0.199SC..THydrogen-bonded Turntrans-63.9-34.2176.6-61.5-178.4000110.4D542 D543 D545 C739D542-I737 WeakPolarHBondContact O-CD1 3.38Å; D543-I737 PolarHBondContact O-N 2.91Å; D543-I737 PolarHBondContact OD1-N 3.41Å; D545-I737 HydrophobicContact CB-CG1 3.84Å; I737-C739 PolarHBondContact O-N 3.1Å; I737-C739 VanDerWaalsContact O-N 3.16Å
738S97.3Very high97.3Very high88 Ų8831.1 Ų31.162%0.61517%0.172SC*.THydrogen-bonded Turntrans-61.7-19.7176.665.40000114.1D543 K736D543-S738 WeakPolarHBondContact OD1-CB 3.33Å; D543-S738 PolarHBondContact OD1-N 3.14Å; D543-S738 PolarHBondContact OD1-OG 2.93Å; K736-S738 PolarHBondContact O-N 3.48Å
739C97.2Very high97.6Very high19 Ų1936.5 Ų36.513%0.12819%0.194CC..  trans-95.4107.5178.7178.20000110.5D714 K736 I737 E741 T742D714-C739 VanDerWaalsContact O-CB 3.3Å; D714-C739 WeakPolarHBondContact O-CB 3.49Å; K736-C739 HydrophobicContact CB-CB 4.48Å; K736-C739 PolarHBondContact O-N 3.28Å; K736-C739 VanDerWaalsContact O-N 3.16Å; I737-C739 PolarHBondContact O-N 3.1Å; I737-C739 VanDerWaalsContact O-N 3.16Å; C739-E741 PolarHBondContact O-N 2.97Å; C739-E741 VanDerWaalsContact O-N 3.15Å; C739-T742 WeakPolarHBondContact CB-OG1 3.28Å; C739-T742 PolarHBondContact O-N 3.4Å; C739-T742 VanDerWaalsContact O-N 3.1Å; C739-T742 PolarHBondContact O-OG1 2.81Å
740S95.6Very high97.7Very high118 Ų11837.8 Ų37.883%0.82520%0.201SC*.THydrogen-bonded Turntrans-65-17.2178.958.70000114.5
741E95.6Very high97.9Very high93 Ų9337.8 Ų37.844%0.43520%0.201SC..THydrogen-bonded Turntrans-78.5-24.5175.8-70.1-175.6-13200112.1M582 K584 C739 R746M582-E741 HydrophobicContact CE-CB 4.21Å; M582-E741 WeakPolarHBondContact CE-O 3.43Å; M582-E741 HydrophobicContact SD-CB 4.08Å; K584-E741 IonicContact NZ-OE2 3.27Å; K584-E741 PolarHBondContact NZ-OE2 3.25Å; C739-E741 PolarHBondContact O-N 2.97Å; C739-E741 VanDerWaalsContact O-N 3.15Å; E741-R746 PolarHBondContact O-NH2 2.94Å
742T97.5Very high97.9Very high11 Ų1140.7 Ų40.77%0.06722%0.215CC..  trans-103.9143.5-176.654.20000113.2M582 Y717 K736 C739M582-T742 HydrophobicContact CE-CG2 3.4Å; Y717-T742 HydrophobicContact CD2-CG2 4.47Å; Y717-T742 HydrophobicContact CE1-CG2 4.16Å; Y717-T742 HydrophobicContact CE2-CG2 4.08Å; Y717-T742 WeakPolarHBondContact OH-CA 3.28Å; K736-T742 PolarHBondContact O-OG1 2.56Å; K736-T742 VanDerWaalsContact O-OG1 3.14Å; C739-T742 WeakPolarHBondContact CB-OG1 3.28Å; C739-T742 PolarHBondContact O-N 3.4Å; C739-T742 VanDerWaalsContact O-N 3.1Å; C739-T742 PolarHBondContact O-OG1 2.81Å
743D98.2Very high98Very high61 Ų6147.7 Ų47.733%0.32624%0.241SC..  trans-153.9117.1173.1177.1-43.5000109.2Y717 H745 R746 F747Y717-D743 PolarHBondContact OH-N 2.85Å; Y717-D743 PolarHBondContact OH-O 3.26Å; D743-H745 VanDerWaalsContact C-N 3.31Å; D743-H745 PolarHBondContact O-N 2.67Å; D743-H745 WeakPolarHBondContact OD1-CA 3.41Å; D743-H745 WeakPolarHBondContact OD1-CB 3.36Å; D743-H745 PolarHBondContact OD1-N 3.23Å; D743-R746 HydrophobicContact CB-CB 3.77Å; D743-R746 PolarHBondContact O-N 3.43Å; D743-R746 WeakPolarHBondContact OD1-CB 3.48Å; D743-R746 PolarHBondContact OD1-N 3.25Å; D743-F747 VanDerWaalsContact O-CB 3.27Å; D743-F747 WeakPolarHBondContact O-CB 3.24Å; D743-F747 PolarHBondContact O-N 2.84Å
744S98.4Very high98Very high0 Ų047.7 Ų47.70%024%0.241CC..Hα-helixtrans-68.3-32.6-171.6-40.60000112.2D545 H547 S735 G748D545-S744 WeakPolarHBondContact CB-OG 3.27Å; D545-S744 PolarHBondContact O-OG 2.83Å; D545-S744 WeakPolarHBondContact OD2-CB 3.13Å; D545-S744 PolarHBondContact OD2-N 3.31Å; D545-S744 PolarHBondContact OD2-OG 3.41Å; H547-S744 WeakPolarHBondContact CB-O 3.46Å; S735-S744 PolarHBondContact N-OG 3.3Å; S735-S744 PolarHBondContact OG-N 3.39Å; S735-S744 PolarHBondContact OG-OG 3.42Å; S744-G748 PolarHBondContact O-N 3.47Å
745H98Very high98Very high55 Ų5547.7 Ų47.726%0.25524%0.241SC..Hα-helixtrans-74.6-45.5179.7-74.472.6000111.2D437 F546 H547 D743 F747 G748 K749D437-H745 IonicContact OD2-CE1 2.79Å; D437-H745 PolarHBondContact OD2-CE1 2.85Å; D437-H745 VanDerWaalsContact OD2-CE1 3.25Å; D437-H745 IonicContact OD2-NE2 2.74Å; D437-H745 PolarHBondContact OD2-NE2 3.01Å; F546-H745 PolarHBondContact O-CE1 2.87Å; H547-H745 AromaticContact CE1-CD2 3.66Å; H547-H745 AromaticContact CG-CD2 3.9Å; H547-H745 AromaticContact CG-CG 3.92Å; H547-H745 AromaticContact ND1-CD2 3.2Å; H547-H745 PolarHBondContact ND1-CD2 3.36Å; H547-H745 AromaticContact ND1-CE1 3.78Å; H547-H745 AromaticContact ND1-CG 3.69Å; H547-H745 AromaticContact ND1-NE2 3.29Å; H547-H745 PolarHBondContact ND1-NE2 3.37Å; D743-H745 VanDerWaalsContact C-N 3.31Å; D743-H745 PolarHBondContact O-N 2.67Å; D743-H745 WeakPolarHBondContact OD1-CA 3.41Å; D743-H745 WeakPolarHBondContact OD1-CB 3.36Å; D743-H745 PolarHBondContact OD1-N 3.23Å; H745-F747 VanDerWaalsContact C-N 3.33Å; H745-G748 PolarHBondContact O-N 2.96Å; H745-K749 WeakPolarHBondContact O-CG 3.39Å; H745-K749 PolarHBondContact O-N 3.02Å
746R98.2Very high98Very high92 Ų9250.6 Ų50.635%0.34726%0.259SS..Hα-helixtrans-60.1-46174.1-170.8-176.272.6-1550.6110.4D581 E741 D743 K749 N750D581-R746 VanDerWaalsContact CG-NH2 3.35Å; D581-R746 IonicContact OD1-CZ 3.31Å; D581-R746 IonicContact OD1-NE 3.53Å; D581-R746 PolarHBondContact OD1-NE 3.01Å; D581-R746 IonicContact OD1-NH2 3.08Å; D581-R746 PolarHBondContact OD1-NH2 2.67Å; D581-R746 IonicContact OD2-CZ 2.7Å; D581-R746 IonicContact OD2-NE 3.67Å; D581-R746 IonicContact OD2-NH2 2.64Å; D581-R746 PolarHBondContact OD2-NH2 3.48Å; E741-R746 PolarHBondContact O-NH2 2.94Å; D743-R746 HydrophobicContact CB-CB 3.77Å; D743-R746 PolarHBondContact O-N 3.43Å; D743-R746 WeakPolarHBondContact OD1-CB 3.48Å; D743-R746 PolarHBondContact OD1-N 3.25Å; R746-K749 PolarHBondContact O-N 3.14Å; R746-N750 PolarHBondContact O-N 2.78Å; R746-N750 PolarHBondContact O-ND2 3.29Å
747F98.6Very high98Very high0 Ų052.6 Ų52.60%027%0.27CS..Hα-helixtrans-65.8-41.1177.9-172.7-137.4000111.8A577 H578 D581 L684 Y717 V719 V733 D743 H745 K749 N750 I751A577-F747 HydrophobicContact CB-CD2 4.3Å; A577-F747 HydrophobicContact CB-CE2 3.71Å; H578-F747 HydrophobicContact CB-CE2 4.02Å; H578-F747 HydrophobicContact CB-CZ 4.23Å; D581-F747 HydrophobicContact CB-CD2 4.08Å; L684-F747 HydrophobicContact CD1-CE1 3.94Å; L684-F747 HydrophobicContact CD1-CZ 4.01Å; Y717-F747 HydrophobicContact CD1-CB 4.32Å; Y717-F747 AromaticContact CD1-CD1 3.56Å; Y717-F747 HydrophobicContact CD1-CD1 3.56Å; Y717-F747 HydrophobicContact CD1-CE1 4.23Å; Y717-F747 HydrophobicContact CD1-CG 4.22Å; Y717-F747 AromaticContact CD2-CD1 3.78Å; Y717-F747 HydrophobicContact CD2-CD1 3.78Å; Y717-F747 AromaticContact CD2-CE1 3.87Å; Y717-F747 HydrophobicContact CD2-CE1 3.87Å; Y717-F747 HydrophobicContact CD2-CG 4.25Å; Y717-F747 HydrophobicContact CD2-CZ 4.43Å; Y717-F747 HydrophobicContact CE1-CB 3.72Å; Y717-F747 AromaticContact CE1-CD1 3.83Å; Y717-F747 HydrophobicContact CE1-CD1 3.83Å; Y717-F747 HydrophobicContact CE1-CG 4.01Å; Y717-F747 HydrophobicContact CE2-CB 4.3Å; Y717-F747 AromaticContact CE2-CD1 3.99Å; Y717-F747 HydrophobicContact CE2-CD1 3.99Å; Y717-F747 HydrophobicContact CE2-CD2 4.38Å; Y717-F747 HydrophobicContact CE2-CE1 4.41Å; Y717-F747 AromaticContact CE2-CG 3.98Å; Y717-F747 HydrophobicContact CE2-CG 3.98Å; Y717-F747 AromaticContact CG-CD1 3.54Å; Y717-F747 HydrophobicContact CG-CD1 3.54Å; Y717-F747 AromaticContact CG-CE1 3.75Å; Y717-F747 HydrophobicContact CG-CE1 3.75Å; Y717-F747 HydrophobicContact CG-CG 4.34Å; Y717-F747 AromaticContact CZ-CG 3.87Å; V719-F747 HydrophobicContact CG2-CD1 4.44Å; V719-F747 HydrophobicContact CG2-CE1 3.67Å; V733-F747 HydrophobicContact CG1-CD1 3.71Å; V733-F747 HydrophobicContact CG1-CE1 4.48Å; D743-F747 VanDerWaalsContact O-CB 3.27Å; D743-F747 WeakPolarHBondContact O-CB 3.24Å; D743-F747 PolarHBondContact O-N 2.84Å; H745-F747 VanDerWaalsContact C-N 3.33Å; F747-K749 PolarHBondContact O-N 3.01Å; F747-N750 CarbonylContact O-C 3.52Å; F747-N750 WeakPolarHBondContact O-CA 3.42Å; F747-N750 WeakPolarHBondContact O-CB 3.46Å; F747-N750 PolarHBondContact O-N 2.76Å; F747-N750 VanDerWaalsContact O-N 3.08Å; F747-I751 HydrophobicContact CD1-CD1 4.18Å; F747-I751 HydrophobicContact CD2-CG1 4.47Å; F747-I751 HydrophobicContact CE1-CD1 4.03Å; F747-I751 HydrophobicContact CE2-CG1 4.23Å; F747-I751 HydrophobicContact CZ-CD1 4.2Å; F747-I751 HydrophobicContact CZ-CG1 4.3Å; F747-I751 WeakPolarHBondContact O-CG1 3.29Å; F747-I751 PolarHBondContact O-N 3.26Å
748G98.4Very high98Very high0 Ų047.8 Ų47.80%025%0.245CC..Hα-helixtrans-55.1-46.3172.400000113.7S744 H745 N750 I751 Q752S744-G748 PolarHBondContact O-N 3.47Å; H745-G748 PolarHBondContact O-N 2.96Å; G748-N750 VanDerWaalsContact C-N 3.32Å; G748-N750 PolarHBondContact O-N 3.44Å; G748-I751 WeakPolarHBondContact O-CB 3.36Å; G748-I751 PolarHBondContact O-N 2.65Å; G748-I751 VanDerWaalsContact O-N 3.13Å; G748-Q752 WeakPolarHBondContact O-CG 3.39Å; G748-Q752 PolarHBondContact O-N 2.97Å
749K98.4Very high98Very high121 Ų12144.1 Ų44.153%0.52622%0.218SC..Hα-helixtrans-60.7-41.3173.7-71170.7-176.3171.90111.9H745 R746 F747 I751 Q752 R753H745-K749 WeakPolarHBondContact O-CG 3.39Å; H745-K749 PolarHBondContact O-N 3.02Å; R746-K749 PolarHBondContact O-N 3.14Å; F747-K749 PolarHBondContact O-N 3.01Å; K749-I751 VanDerWaalsContact C-N 3.32Å; K749-I751 PolarHBondContact O-N 2.69Å; K749-Q752 PolarHBondContact O-N 3.34Å; K749-R753 WeakPolarHBondContact O-CB 3.22Å; K749-R753 PolarHBondContact O-N 3.39Å
750N98.6Very high97.9Very high26 Ų2645 Ų4514%0.13923%0.227CC..Hα-helixtrans-63.6-36.2174.9-80.2-34.2000112.2A577 D581 R746 F747 G748 A754A577-N750 HydrophobicContact CB-CB 4.02Å; D581-N750 PolarHBondContact OD1-ND2 2.95Å; R746-N750 PolarHBondContact O-N 2.78Å; R746-N750 PolarHBondContact O-ND2 3.29Å; F747-N750 CarbonylContact O-C 3.52Å; F747-N750 WeakPolarHBondContact O-CA 3.42Å; F747-N750 WeakPolarHBondContact O-CB 3.46Å; F747-N750 PolarHBondContact O-N 2.76Å; F747-N750 VanDerWaalsContact O-N 3.08Å; G748-N750 VanDerWaalsContact C-N 3.32Å; G748-N750 PolarHBondContact O-N 3.44Å; N750-A754 WeakPolarHBondContact O-CB 3.5Å; N750-A754 PolarHBondContact O-N 3.04Å
751I98.8Very high97.9Very high0 Ų039.9 Ų39.90%019%0.19CC..Hα-helixtrans-63.2-51.7173.2-65.5169.1000110.4F549 L574 A577 F731 V733 F747 G748 K749 R753 A754 M755F549-I751 HydrophobicContact CZ-CB 4.39Å; F549-I751 HydrophobicContact CZ-CG2 4.34Å; L574-I751 HydrophobicContact CD2-CD1 3.6Å; L574-I751 HydrophobicContact CD2-CG1 3.74Å; L574-I751 HydrophobicContact CD2-CG2 4.19Å; A577-I751 HydrophobicContact CB-CB 4.46Å; A577-I751 HydrophobicContact CB-CG1 3.85Å; F731-I751 HydrophobicContact CD1-CG2 4.23Å; F731-I751 HydrophobicContact CE1-CG2 3.97Å; F731-I751 HydrophobicContact CE2-CG2 4.37Å; F731-I751 HydrophobicContact CZ-CG2 4.05Å; V733-I751 HydrophobicContact CG2-CD1 3.85Å; F747-I751 HydrophobicContact CD1-CD1 4.18Å; F747-I751 HydrophobicContact CD2-CG1 4.47Å; F747-I751 HydrophobicContact CE1-CD1 4.03Å; F747-I751 HydrophobicContact CE2-CG1 4.23Å; F747-I751 HydrophobicContact CZ-CD1 4.2Å; F747-I751 HydrophobicContact CZ-CG1 4.3Å; F747-I751 WeakPolarHBondContact O-CG1 3.29Å; F747-I751 PolarHBondContact O-N 3.26Å; G748-I751 WeakPolarHBondContact O-CB 3.36Å; G748-I751 PolarHBondContact O-N 2.65Å; G748-I751 VanDerWaalsContact O-N 3.13Å; K749-I751 VanDerWaalsContact C-N 3.32Å; K749-I751 PolarHBondContact O-N 2.69Å; I751-R753 VanDerWaalsContact C-N 3.29Å; I751-R753 PolarHBondContact O-N 3.1Å; I751-A754 PolarHBondContact O-N 3.48Å; I751-M755 HydrophobicContact CG2-CG 4.32Å; I751-M755 WeakPolarHBondContact O-CB 3.38Å; I751-M755 VanDerWaalsContact O-CG 3.24Å; I751-M755 WeakPolarHBondContact O-CG 2.81Å; I751-M755 PolarHBondContact O-N 2.87Å
752Q98.6Very high97.6Very high62 Ų6237 Ų3729%0.2918%0.176SC..Hα-helixtrans-57.5-42.8178.9-67.4176-44.200112F549 F551 G748 K749 T756F549-Q752 HydrophobicContact CD2-CG 4.05Å; F549-Q752 HydrophobicContact CE2-CG 3.42Å; F549-Q752 VanDerWaalsContact CE2-CG 3.42Å; F549-Q752 HydrophobicContact CZ-CG 4.01Å; F551-Q752 HydrophobicContact CD2-CB 4.44Å; F551-Q752 HydrophobicContact CD2-CG 4.2Å; G748-Q752 WeakPolarHBondContact O-CG 3.39Å; G748-Q752 PolarHBondContact O-N 2.97Å; K749-Q752 PolarHBondContact O-N 3.34Å; Q752-T756 PolarHBondContact O-N 3.21Å; Q752-T756 VanDerWaalsContact O-N 3.16Å; Q752-T756 PolarHBondContact O-OG1 2.92Å; Q752-T756 VanDerWaalsContact O-OG1 3.05Å
753R98.6Very high96.5Very high150 Ų15040.2 Ų40.257%0.56620%0.2SC*.Hα-helixtrans-65.3-47.3176.3-173.2-179.1174.4179.70.3111.7K749 I751 M755 T756 D757K749-R753 WeakPolarHBondContact O-CB 3.22Å; K749-R753 PolarHBondContact O-N 3.39Å; I751-R753 VanDerWaalsContact C-N 3.29Å; I751-R753 PolarHBondContact O-N 3.1Å; R753-M755 VanDerWaalsContact C-N 3.35Å; R753-M755 PolarHBondContact O-N 2.95Å; R753-T756 PolarHBondContact O-N 3.15Å; R753-D757 IonicContact NE-OD2 2.79Å; R753-D757 WeakPolarHBondContact O-CB 3.36Å; R753-D757 VanDerWaalsContact O-CG 3.22Å; R753-D757 PolarHBondContact O-N 3.38Å
754A98.8Very high94.5Very high0 Ų045.6 Ų45.60%022%0.215CC..Hα-helixtrans-59.6-44.917800000111.5A573 L576 A577 N750 I751 T756 D757 I758A573-A754 HydrophobicContact CB-CB 4.21Å; A573-A754 WeakPolarHBondContact O-CB 3.1Å; L576-A754 HydrophobicContact CB-CB 4.13Å; L576-A754 HydrophobicContact CD2-CB 3.96Å; L576-A754 HydrophobicContact CG-CB 4.05Å; A577-A754 HydrophobicContact CB-CB 4.06Å; N750-A754 WeakPolarHBondContact O-CB 3.5Å; N750-A754 PolarHBondContact O-N 3.04Å; I751-A754 PolarHBondContact O-N 3.48Å; A754-T756 VanDerWaalsContact C-N 3.34Å; A754-T756 PolarHBondContact O-N 3.31Å; A754-D757 PolarHBondContact O-N 3.17Å; A754-I758 WeakPolarHBondContact O-CB 3.36Å; A754-I758 WeakPolarHBondContact O-CG1 3.45Å; A754-I758 PolarHBondContact O-N 3.45Å
755M98.5Very high92.2Very high0 Ų049 Ų490%024%0.239CC..Hα-helixtrans-55.3-49.6175.6-70.6-70.3-7300111.4F551 F554 I559 F569 V570 A573 I729 I751 R753 M759F551-M755 HydrophobicContact CD1-CE 4.41Å; F551-M755 HydrophobicContact CE1-CB 4.34Å; F551-M755 HydrophobicContact CE1-CE 4.15Å; F551-M755 HydrophobicContact CE2-CB 3.98Å; F551-M755 HydrophobicContact CZ-CB 3.74Å; F554-M755 HydrophobicContact CE2-CE 3.82Å; F554-M755 HydrophobicContact CZ-CB 4.05Å; F554-M755 HydrophobicContact CZ-CE 4.16Å; F554-M755 WeakPolarHBondContact CZ-O 3.29Å; I559-M755 HydrophobicContact CD1-CE 4.49Å; F569-M755 HydrophobicContact CD1-CE 4.01Å; F569-M755 HydrophobicContact CD1-SD 3.83Å; F569-M755 HydrophobicContact CE1-CE 3.87Å; F569-M755 HydrophobicContact CE1-SD 3.68Å; V570-M755 HydrophobicContact CG2-CE 4.08Å; V570-M755 HydrophobicContact CG2-SD 4.27Å; A573-M755 HydrophobicContact CB-CG 3.96Å; A573-M755 HydrophobicContact CB-SD 3.43Å; A573-M755 WeakPolarHBondContact CB-SD 3.49Å; I729-M755 HydrophobicContact CD1-CE 3.76Å; I751-M755 HydrophobicContact CG2-CG 4.32Å; I751-M755 WeakPolarHBondContact O-CB 3.38Å; I751-M755 VanDerWaalsContact O-CG 3.24Å; I751-M755 WeakPolarHBondContact O-CG 2.81Å; I751-M755 PolarHBondContact O-N 2.87Å; R753-M755 VanDerWaalsContact C-N 3.35Å; R753-M755 PolarHBondContact O-N 2.95Å; M755-M759 PolarHBondContact O-N 3.23Å; M755-M759 VanDerWaalsContact O-N 3.16Å
756T98.3Very high89.6Confident61 Ų6154.6 Ų54.637%0.37426%0.263SS..Hα-helixtrans-66.9-44-179.3-56.80000112.6Q752 R753 A754 I758 M759 A760Q752-T756 PolarHBondContact O-N 3.21Å; Q752-T756 VanDerWaalsContact O-N 3.16Å; Q752-T756 PolarHBondContact O-OG1 2.92Å; Q752-T756 VanDerWaalsContact O-OG1 3.05Å; R753-T756 PolarHBondContact O-N 3.15Å; A754-T756 VanDerWaalsContact C-N 3.34Å; A754-T756 PolarHBondContact O-N 3.31Å; T756-I758 PolarHBondContact O-N 2.92Å; T756-M759 PolarHBondContact O-N 3.02Å; T756-A760 PolarHBondContact O-N 3.07Å
757D98Very high86.8Confident46 Ų4657.2 Ų57.225%0.24628%0.284CS..Hα-helixtrans-63-43-179.8-72.8-12.8000111.8R580 M619 R753 A754 M759 A760R580-D757 IonicContact CZ-OD2 3.42Å; R580-D757 IonicContact NH1-OD2 3.22Å; R580-D757 PolarHBondContact NH1-OD2 2.6Å; R580-D757 IonicContact NH2-OD2 2.75Å; R580-D757 PolarHBondContact NH2-OD2 2.95Å; M619-D757 HydrophobicContact CE-CB 3.95Å; R753-D757 IonicContact NE-OD2 2.79Å; R753-D757 WeakPolarHBondContact O-CB 3.36Å; R753-D757 VanDerWaalsContact O-CG 3.22Å; R753-D757 PolarHBondContact O-N 3.38Å; A754-D757 PolarHBondContact O-N 3.17Å; D757-M759 VanDerWaalsContact C-N 3.32Å; D757-M759 PolarHBondContact O-N 3.23Å; D757-A760 WeakPolarHBondContact O-CB 3.39Å; D757-A760 PolarHBondContact O-N 3.17Å
758I97.9Very high83.8Confident0 Ų062.7 Ų62.70%032%0.321CS..Hα-helixtrans-63.4-41.4176.2-64.5178.3000110.3F569 A573 L576 F615 M619 L633 A754 T756 A760 L761 F762F569-I758 HydrophobicContact CD2-CG2 4.11Å; F569-I758 HydrophobicContact CE1-CB 4.46Å; F569-I758 HydrophobicContact CE1-CG2 4.33Å; F569-I758 HydrophobicContact CE2-CB 4.2Å; F569-I758 HydrophobicContact CE2-CG2 3.37Å; F569-I758 HydrophobicContact CZ-CB 3.79Å; F569-I758 HydrophobicContact CZ-CG2 3.49Å; F569-I758 VanDerWaalsContact CZ-CG2 3.49Å; A573-I758 HydrophobicContact CB-CD1 3.92Å; L576-I758 HydrophobicContact CD2-CD1 4.11Å; L576-I758 HydrophobicContact CD2-CG1 3.96Å; F615-I758 HydrophobicContact CE1-CD1 4.04Å; F615-I758 HydrophobicContact CZ-CD1 3.83Å; F615-I758 HydrophobicContact CZ-CG1 3.9Å; M619-I758 HydrophobicContact CE-CG1 4.46Å; L633-I758 HydrophobicContact CD1-CG2 3.93Å; L633-I758 HydrophobicContact CD2-CG2 3.71Å; A754-I758 WeakPolarHBondContact O-CB 3.36Å; A754-I758 WeakPolarHBondContact O-CG1 3.45Å; A754-I758 PolarHBondContact O-N 3.45Å; T756-I758 PolarHBondContact O-N 2.92Å; I758-A760 VanDerWaalsContact C-N 3.31Å; I758-A760 PolarHBondContact O-N 3.3Å; I758-L761 WeakPolarHBondContact O-CB 3.44Å; I758-L761 PolarHBondContact O-N 2.95Å; I758-F762 WeakPolarHBondContact O-CD2 3.45Å
759M97.1Very high80.8Confident11 Ų1168.7 Ų68.75%0.05436%0.357CS..Hα-helixtrans-65.9-34177.7-169.357.270.900112.3F554 L558 I559 T562 F569 M755 T756 D757 L761 F762F554-M759 HydrophobicContact CD1-CB 4.48Å; F554-M759 HydrophobicContact CD1-CE 4.43Å; F554-M759 HydrophobicContact CD1-CG 4.21Å; F554-M759 HydrophobicContact CD2-CE 3.71Å; F554-M759 HydrophobicContact CE1-CB 3.69Å; F554-M759 HydrophobicContact CE1-CE 4.24Å; F554-M759 HydrophobicContact CE1-CG 3.91Å; F554-M759 HydrophobicContact CE2-CE 3.49Å; F554-M759 VanDerWaalsContact CE2-CE 3.49Å; F554-M759 HydrophobicContact CG-CE 4.19Å; F554-M759 HydrophobicContact CZ-CB 3.82Å; F554-M759 HydrophobicContact CZ-CE 3.78Å; F554-M759 HydrophobicContact CZ-CG 4.22Å; L558-M759 HydrophobicContact CB-CE 4.26Å; L558-M759 HydrophobicContact CD2-CE 3.93Å; L558-M759 HydrophobicContact CD2-CG 3.78Å; L558-M759 HydrophobicContact CD2-SD 3.69Å; L558-M759 HydrophobicContact CG-CE 3.8Å; L558-M759 HydrophobicContact CG-CG 4.45Å; L558-M759 HydrophobicContact CG-SD 3.69Å; I559-M759 HydrophobicContact CG1-CE 3.85Å; T562-M759 HydrophobicContact CG2-CE 4.35Å; T562-M759 HydrophobicContact CG2-SD 3.88Å; F569-M759 HydrophobicContact CE2-CE 4.03Å; F569-M759 HydrophobicContact CZ-CB 4.36Å; F569-M759 HydrophobicContact CZ-CE 3.87Å; M755-M759 PolarHBondContact O-N 3.23Å; M755-M759 VanDerWaalsContact O-N 3.16Å; T756-M759 PolarHBondContact O-N 3.02Å; D757-M759 VanDerWaalsContact C-N 3.32Å; D757-M759 PolarHBondContact O-N 3.23Å; M759-L761 VanDerWaalsContact C-N 3.25Å; M759-L761 PolarHBondContact O-N 2.87Å; M759-F762 PolarHBondContact O-N 2.79Å; M759-F762 VanDerWaalsContact O-N 3.15Å
760A95.9Very high77.6Confident38 Ų3876.2 Ų76.231%0.31439%0.39SS..Hα-helixtrans-62.4-29.6179.200000113.2T756 D757 I758 F762 S763 R764T756-A760 PolarHBondContact O-N 3.07Å; D757-A760 WeakPolarHBondContact O-CB 3.39Å; D757-A760 PolarHBondContact O-N 3.17Å; I758-A760 VanDerWaalsContact C-N 3.31Å; I758-A760 PolarHBondContact O-N 3.3Å; A760-F762 PolarHBondContact O-N 2.93Å; A760-S763 PolarHBondContact O-N 3.44Å; A760-S763 VanDerWaalsContact O-N 3.16Å; A760-R764 PolarHBondContact O-N 2.96Å
761L94.9Very high76.6Confident11 Ų1178.8 Ų78.86%0.05840%0.403CS..Hα-helixtrans-56.2-36.3174.6-64.7179.3000112.5M619 N626 K629 L633 I758 M759M619-L761 HydrophobicContact SD-CD1 3.71Å; M619-L761 HydrophobicContact SD-CD2 4.18Å; M619-L761 HydrophobicContact SD-CG 4.24Å; N626-L761 HydrophobicContact CB-CD2 4.42Å; K629-L761 HydrophobicContact CB-CD1 4.12Å; K629-L761 HydrophobicContact CB-CD2 4.06Å; K629-L761 HydrophobicContact CD-CD2 4.21Å; L633-L761 HydrophobicContact CD2-CD1 4.37Å; I758-L761 WeakPolarHBondContact O-CB 3.44Å; I758-L761 PolarHBondContact O-N 2.95Å; M759-L761 VanDerWaalsContact C-N 3.25Å; M759-L761 PolarHBondContact O-N 2.87Å
762F90.6Very high75.4Confident31 Ų3182.9 Ų82.914%0.13642%0.424CS..Hα-helixtrans-80.9-24.7-178.1-63.2-85.8000113.2T562 F569 L630 L633 I758 M759 A760T562-F762 VanDerWaalsContact CB-CE1 3.44Å; T562-F762 HydrophobicContact CG2-CB 4.18Å; T562-F762 HydrophobicContact CG2-CD1 3.85Å; T562-F762 HydrophobicContact CG2-CD2 3.72Å; T562-F762 HydrophobicContact CG2-CE1 4.08Å; T562-F762 HydrophobicContact CG2-CE2 3.98Å; T562-F762 HydrophobicContact CG2-CG 3.64Å; T562-F762 HydrophobicContact CG2-CZ 4.14Å; F569-F762 HydrophobicContact CE2-CE2 4.41Å; L630-F762 HydrophobicContact CD1-CD1 3.77Å; L630-F762 HydrophobicContact CD1-CE1 3.22Å; L630-F762 HydrophobicContact CD1-CE2 4.2Å; L630-F762 HydrophobicContact CD1-CG 4.47Å; L630-F762 HydrophobicContact CD1-CZ 3.48Å; L630-F762 VanDerWaalsContact CD1-CZ 3.48Å; L633-F762 HydrophobicContact CD2-CE2 3.47Å; L633-F762 VanDerWaalsContact CD2-CE2 3.47Å; L633-F762 HydrophobicContact CD2-CZ 3.43Å; L633-F762 VanDerWaalsContact CD2-CZ 3.43Å; I758-F762 WeakPolarHBondContact O-CD2 3.45Å; M759-F762 PolarHBondContact O-N 2.79Å; M759-F762 VanDerWaalsContact O-N 3.15Å; A760-F762 PolarHBondContact O-N 2.93Å
763S73.1Confident74.1Confident80 Ų8084.1 Ų84.156%0.55943%0.431SS*.Hα-helixtrans-78-34-178.1-60.10000112A760A760-S763 PolarHBondContact O-N 3.44Å; A760-S763 VanDerWaalsContact O-N 3.16Å
764R57.1Low72.7Confident173 Ų17380.2 Ų80.265%0.65342%0.423SS*.Hα-helixtrans-78.9-20.6-179.7-68.1-178.4175.9-178.8-1.5114A760 K766 N767A760-R764 PolarHBondContact O-N 2.96Å; R764-K766 VanDerWaalsContact C-N 3.25Å; R764-K766 PolarHBondContact O-N 3.46Å; R764-N767 PolarHBondContact O-N 3.13Å
765S49.3Very low71.1Confident72 Ų7285.2 Ų85.250%0.50345%0.45SS..G310 helixtrans-66.3-20.2178165.80000114.2N767S765-N767 VanDerWaalsContact C-N 3.32Å; S765-N767 PolarHBondContact O-N 3.06Å
766K45.1Very low69.2Low173 Ų17390.9 Ų90.975%0.75248%0.48SS*.G310 helixtrans-75.1-15180-76.4-172.2177-178.50114.7R764R764-K766 VanDerWaalsContact C-N 3.25Å; R764-K766 PolarHBondContact O-N 3.46Å
767N37.9Very low67.2Low147 Ų14793 Ų9379%0.78649%0.487SS*.G310 helixtrans-94.83.6-176.8-74.4-6.2000114.4R764 S765R764-N767 PolarHBondContact O-N 3.13Å; S765-N767 VanDerWaalsContact C-N 3.32Å; S765-N767 PolarHBondContact O-N 3.06Å
768C35.4Very low64.8Low115 Ų11596.6 Ų96.678%0.77751%0.506SS*.SBendtrans-107.714.4-179.4-81.20000115.2
769T35.8Very low62Low125 Ų125104.7 Ų104.777%0.76755%0.548SS*.  trans-118.788.816441.50000109.1
770K32.2Very low58.8Low280 Ų280113.2 Ų113.2100%1.21759%0.593SS**  trans-114.40149.5-97.7-169.2177-177.40107.8

Retrieved 770 of 770 residues in 618.4 ms (Link to these results)