A0A093GZQ1_STRCA Loading...

Retinoic acid-induced protein 3

AlphaFold DB , UniProt , Accession A0A093GZQ1, Species STRCA (Struthio camelus australis), Gene n/a, Length 356 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	33.3	Very low	62.1	Low	240 Å²	240	98.4 Å²	98.4	100%	1.182	63%	0.627	S	S	*	*				0	117.6	0	-80.7	174	-175.2	0	0	107.7	T3	M1-T3 PolarHBondContact O-N 3.27Å
2	A	41.6	Very low	62.9	Low	109 Å²	109	96.2 Å²	96.2	90%	0.901	61%	0.605	S	S	*	*			trans	-71.2	109.5	174.2	0	0	0	0	0	108.3	A4	A2-A4 PolarHBondContact O-N 2.89Å
3	T	57.9	Low	63.3	Low	94 Å²	94	93.3 Å²	93.3	58%	0.577	60%	0.596	S	S	*	*	P	Polyproline II helix	trans	-63.4	125.7	172.7	47.1	0	0	0	0	108.8	M1	M1-T3 PolarHBondContact O-N 3.27Å
4	A	66.9	Low	63.2	Low	88 Å²	88	89 Å²	89	73%	0.727	57%	0.573	S	S	*	*	P	Polyproline II helix	trans	-54	140.5	173.9	0	0	0	0	0	110	A2	A2-A4 PolarHBondContact O-N 2.89Å
5	P	68.1	Low	63.1	Low	66 Å²	66	86.3 Å²	86.3	43%	0.429	55%	0.552	S	S	.	*	P	Polyproline II helix	trans	-61.4	137.4	178.8	23.3	-31.1	0	0	0	110.6	C9 Y17	P5-C9 HydrophobicContact CB-CB 3.92Å; P5-Y17 HydrophobicContact CB-CE1 3.98Å; P5-Y17 HydrophobicContact CB-CE2 4.4Å
6	P	69.4	Low	63	Low	34 Å²	34	87.8 Å²	87.8	22%	0.221	55%	0.545	C	S	.	.	P	Polyproline II helix	trans	-64.8	160.9	176.5	17.5	-19.5	0	0	0	111.5	G8 C9 Y17 D21	P6-G8 PolarHBondContact O-N 3.25Å; P6-G8 VanDerWaalsContact O-N 3.15Å; P6-C9 HydrophobicContact CG-CB 4.38Å; P6-C9 WeakPolarHBondContact O-CB 3.38Å; P6-C9 PolarHBondContact O-N 3.14Å; P6-Y17 VanDerWaalsContact CD-CG 3.49Å; P6-Y17 HydrophobicContact CG-CD2 4.06Å; P6-Y17 HydrophobicContact CG-CG 3.91Å; P6-D21 HydrophobicContact CB-CB 4.22Å; P6-D21 HydrophobicContact CG-CB 4.11Å
7	R	65.6	Low	63.2	Low	199 Å²	199	85.1 Å²	85.1	75%	0.751	52%	0.522	S	S	*	.	T	Hydrogen-bonded Turn	trans	-60.5	118.6	-177.6	-78.4	-179.3	143.5	175.3	-5.4	110.5	M22	R7-M22 PolarHBondContact O-N 3.17Å
8	G	66.3	Low	63.1	Low	61 Å²	61	83.2 Å²	83.2	63%	0.629	51%	0.508	S	S	*	.	T	Hydrogen-bonded Turn	trans	109.5	-19.3	-176.3	0	0	0	0	0	113.8	P6 C20	P6-G8 PolarHBondContact O-N 3.25Å; P6-G8 VanDerWaalsContact O-N 3.15Å; G8-C20 CarbonylContact C-O 3.32Å; G8-C20 VanDerWaalsContact C-O 3.32Å; G8-C20 WeakPolarHBondContact CA-O 3.4Å
9	C	70.1	Confident	63	Low	16 Å²	16	81 Å²	81	11%	0.108	49%	0.493	C	S	.	.			trans	-86	130.6	174.9	-64.5	0	0	0	0	112	P5 P6 Y17 C20	P5-C9 HydrophobicContact CB-CB 3.92Å; P6-C9 HydrophobicContact CG-CB 4.38Å; P6-C9 WeakPolarHBondContact O-CB 3.38Å; P6-C9 PolarHBondContact O-N 3.14Å; C9-Y17 HydrophobicContact CB-CD1 3.91Å; C9-Y17 HydrophobicContact CB-CE1 4.15Å; C9-Y17 PolarHBondContact SG-O 3.05Å; C9-C20 HydrophobicContact CB-CB 4.22Å; C9-C20 VanDerWaalsContact SG-C 3.5Å; C9-C20 WeakPolarHBondContact SG-CB 3.32Å
10	G	72.2	Confident	62.7	Low	44 Å²	44	79 Å²	79	45%	0.454	48%	0.482	S	S	.	.			trans	-78.4	-157.7	164.2	0	0	0	0	0	112.5	I12	G10-I12 PolarHBondContact O-N 3.43Å
11	S	72.1	Confident	62.8	Low	131 Å²	131	76.2 Å²	76.2	92%	0.916	46%	0.464	S	S	*	.	S	Bend	trans	-77	57.4	174.1	79	0	0	0	0	112.4
12	I	70.9	Confident	64	Low	72 Å²	72	71.1 Å²	71.1	37%	0.369	44%	0.439	S	S	.	.			trans	-93.7	154.3	176.9	-45.7	175.7	0	0	0	108	G10 Y16 Y17	G10-I12 PolarHBondContact O-N 3.43Å; I12-Y16 HydrophobicContact CG2-CD2 4.08Å; I12-Y16 HydrophobicContact CG2-CG 4.18Å; I12-Y17 WeakPolarHBondContact O-CE1 3.48Å
13	A	69	Low	64.9	Low	59 Å²	59	72.7 Å²	72.7	49%	0.488	43%	0.428	S	S	.	.			trans	-58.9	143.1	175.4	0	0	0	0	0	110.8	D15 Y16	A13-D15 PolarHBondContact O-N 3.28Å; A13-Y16 HydrophobicContact CB-CD2 4Å; A13-Y16 HydrophobicContact CB-CE2 4.23Å; A13-Y16 PolarHBondContact O-N 3.32Å
14	A	61.8	Low	65.1	Low	33 Å²	33	71.3 Å²	71.3	27%	0.273	42%	0.415	S	S	.	.	G	3₁₀ helix	trans	-59.2	-16.1	-172.7	0	0	0	0	0	114.6	Y16 Y17	A14-Y16 VanDerWaalsContact C-N 3.3Å; A14-Y17 HydrophobicContact CB-CD2 3.97Å; A14-Y17 HydrophobicContact CB-CE2 3.65Å
15	D	60.8	Low	65.3	Low	48 Å²	48	70.4 Å²	70.4	26%	0.257	41%	0.408	S	S	.	.	G	3₁₀ helix	trans	-72	-24	176.2	-62.8	-14.7	0	0	0	112.8	A13 K87 N89	A13-D15 PolarHBondContact O-N 3.28Å; D15-K87 HydrophobicContact CB-CB 4.17Å; D15-K87 WeakPolarHBondContact O-CB 2.9Å; D15-K87 PolarHBondContact O-N 2.89Å; D15-N89 PolarHBondContact OD2-ND2 2.91Å
16	Y	62.1	Low	65.5	Low	111 Å²	111	70.7 Å²	70.7	44%	0.435	40%	0.4	S	S	.	.	G	3₁₀ helix	trans	-97.4	1.4	-178.7	-59.3	-83.9	0	0	0	113.1	I12 A13 A14 L18 L19 I86	I12-Y16 HydrophobicContact CG2-CD2 4.08Å; I12-Y16 HydrophobicContact CG2-CG 4.18Å; A13-Y16 HydrophobicContact CB-CD2 4Å; A13-Y16 HydrophobicContact CB-CE2 4.23Å; A13-Y16 PolarHBondContact O-N 3.32Å; A14-Y16 VanDerWaalsContact C-N 3.3Å; Y16-L18 PolarHBondContact O-N 3.39Å; Y16-L19 HydrophobicContact CD1-CD1 3.85Å; Y16-L19 WeakPolarHBondContact O-CB 3.46Å; Y16-L19 PolarHBondContact O-N 3.45Å; Y16-I86 HydrophobicContact CD1-CD1 4.27Å; Y16-I86 HydrophobicContact CD1-CG1 4.09Å; Y16-I86 HydrophobicContact CD1-CG2 4.09Å; Y16-I86 HydrophobicContact CE1-CD1 4.08Å; Y16-I86 HydrophobicContact CE1-CG1 4.33Å; Y16-I86 HydrophobicContact CE1-CG2 4.08Å
17	Y	66.9	Low	65.7	Low	41 Å²	41	69.2 Å²	69.2	16%	0.161	39%	0.391	C	S	.	.	H	α-helix	trans	-59.4	-32.4	-176.2	-73.2	-11.9	0	0	0	113.2	P5 P6 C9 I12 A14 L19 C20 D21	P5-Y17 HydrophobicContact CB-CE1 3.98Å; P5-Y17 HydrophobicContact CB-CE2 4.4Å; P6-Y17 VanDerWaalsContact CD-CG 3.49Å; P6-Y17 HydrophobicContact CG-CD2 4.06Å; P6-Y17 HydrophobicContact CG-CG 3.91Å; C9-Y17 HydrophobicContact CB-CD1 3.91Å; C9-Y17 HydrophobicContact CB-CE1 4.15Å; C9-Y17 PolarHBondContact SG-O 3.05Å; I12-Y17 WeakPolarHBondContact O-CE1 3.48Å; A14-Y17 HydrophobicContact CB-CD2 3.97Å; A14-Y17 HydrophobicContact CB-CE2 3.65Å; Y17-L19 PolarHBondContact O-N 3.46Å; Y17-C20 CarbonylContact O-C 3.56Å; Y17-C20 PolarHBondContact O-N 3.4Å; Y17-D21 WeakPolarHBondContact O-CB 3.46Å; Y17-D21 PolarHBondContact O-N 3.28Å
18	L	60.5	Low	66.3	Low	51 Å²	51	63.1 Å²	63.1	27%	0.267	37%	0.373	S	S	.	.	H	α-helix	trans	-63.2	-19	176.1	-81.6	145	0	0	0	114.6	Y16 W26 I85 K87	Y16-L18 PolarHBondContact O-N 3.39Å; L18-W26 HydrophobicContact CD2-CZ2 4.3Å; L18-I85 WeakPolarHBondContact CB-O 3.35Å; L18-K87 HydrophobicContact CD1-CB 4.14Å; L18-K87 HydrophobicContact CD1-CG 4.38Å
19	L	60.8	Low	67.2	Low	42 Å²	42	64.1 Å²	64.1	22%	0.22	37%	0.367	C	S	.	.	H	α-helix	trans	-82.2	-23.2	174.3	-71.6	156.8	0	0	0	112.8	Y16 Y17 F82 I85 I86	Y16-L19 HydrophobicContact CD1-CD1 3.85Å; Y16-L19 WeakPolarHBondContact O-CB 3.46Å; Y16-L19 PolarHBondContact O-N 3.45Å; Y17-L19 PolarHBondContact O-N 3.46Å; L19-F82 HydrophobicContact CD2-CD1 4.33Å; L19-I85 HydrophobicContact CD2-CG2 3.76Å; L19-I85 HydrophobicContact CG-CG2 4.08Å; L19-I86 HydrophobicContact CD1-CD1 4.22Å; L19-I86 HydrophobicContact CD1-CG1 3.56Å; L19-I86 HydrophobicContact CG-CG1 4.19Å
20	C	58.3	Low	67.9	Low	41 Å²	41	64 Å²	64	28%	0.277	37%	0.365	S	S	.	.	H	α-helix	trans	-121	-0	-173	-60.3	0	0	0	0	112.2	G8 C9 Y17 M22	G8-C20 CarbonylContact C-O 3.32Å; G8-C20 VanDerWaalsContact C-O 3.32Å; G8-C20 WeakPolarHBondContact CA-O 3.4Å; C9-C20 HydrophobicContact CB-CB 4.22Å; C9-C20 VanDerWaalsContact SG-C 3.5Å; C9-C20 WeakPolarHBondContact SG-CB 3.32Å; Y17-C20 CarbonylContact O-C 3.56Å; Y17-C20 PolarHBondContact O-N 3.4Å; C20-M22 PolarHBondContact O-N 3.36Å
21	D	63.9	Low	68.6	Low	21 Å²	21	64.7 Å²	64.7	11%	0.112	36%	0.356	C	S	.	.			trans	-75.3	101.7	176.2	-177.7	8.7	0	0	0	109.9	P6 Y17 E23 Q24	P6-D21 HydrophobicContact CB-CB 4.22Å; P6-D21 HydrophobicContact CG-CB 4.11Å; Y17-D21 WeakPolarHBondContact O-CB 3.46Å; Y17-D21 PolarHBondContact O-N 3.28Å; D21-E23 PolarHBondContact O-N 3.3Å; D21-E23 WeakPolarHBondContact OD1-CB 3.01Å; D21-E23 PolarHBondContact OD1-N 2.88Å; D21-Q24 PolarHBondContact O-N 2.95Å; D21-Q24 PolarHBondContact OD2-NE2 3.39Å; D21-Q24 VanDerWaalsContact OD2-NE2 3.09Å
22	M	59.5	Low	69.4	Low	133 Å²	133	61.7 Å²	61.7	66%	0.655	34%	0.335	S	S	*	.	T	Hydrogen-bonded Turn	trans	-72.3	-7.1	-179.4	-66.4	-74.4	-78.6	0	0	113.2	R7 C20 I28	R7-M22 PolarHBondContact O-N 3.17Å; C20-M22 PolarHBondContact O-N 3.36Å; M22-I28 HydrophobicContact SD-CD1 4.02Å
23	E	59.2	Low	70.5	Confident	142 Å²	142	61.6 Å²	61.6	66%	0.664	34%	0.335	S	S	*	.	T	Hydrogen-bonded Turn	trans	-82.3	-16.8	179.2	-60.4	-167.5	168.8	0	0	112.5	D21	D21-E23 PolarHBondContact O-N 3.3Å; D21-E23 WeakPolarHBondContact OD1-CB 3.01Å; D21-E23 PolarHBondContact OD1-N 2.88Å
24	Q	63.8	Low	71.5	Confident	65 Å²	65	58.8 Å²	58.8	30%	0.304	31%	0.312	S	S	.	.			trans	-104.4	83.8	-178.8	-69.5	-169.7	62.5	0	0	112.3	D21 W26 G27	D21-Q24 PolarHBondContact O-N 2.95Å; D21-Q24 PolarHBondContact OD2-NE2 3.39Å; D21-Q24 VanDerWaalsContact OD2-NE2 3.09Å; Q24-W26 PolarHBondContact O-N 3.05Å; Q24-W26 VanDerWaalsContact O-N 3.07Å; Q24-G27 PolarHBondContact O-N 3.36Å
25	A	69.7	Low	73	Confident	69 Å²	69	59.2 Å²	59.2	57%	0.57	32%	0.315	S	S	*	.	H	α-helix	trans	-54.8	-29.4	-178.2	0	0	0	0	0	114.7	V29	A25-V29 VanDerWaalsContact O-CG2 3.31Å; A25-V29 WeakPolarHBondContact O-CG2 3.36Å; A25-V29 PolarHBondContact O-N 2.99Å
26	W	72.8	Confident	74.6	Confident	71 Å²	71	58.9 Å²	58.9	27%	0.269	32%	0.319	S	S	.	.	H	α-helix	trans	-68.2	-35.7	178.2	71.5	-90.8	0	0	0	112.4	L18 Q24 L30 P244	L18-W26 HydrophobicContact CD2-CZ2 4.3Å; Q24-W26 PolarHBondContact O-N 3.05Å; Q24-W26 VanDerWaalsContact O-N 3.07Å; W26-L30 HydrophobicContact CE3-CD1 3.56Å; W26-L30 HydrophobicContact CZ3-CD1 3.84Å; W26-L30 WeakPolarHBondContact O-CB 3.39Å; W26-L30 WeakPolarHBondContact O-CG 3.44Å; W26-L30 PolarHBondContact O-N 2.92Å; W26-P244 HydrophobicContact CD2-CB 4.21Å; W26-P244 HydrophobicContact CD2-CG 4.3Å; W26-P244 HydrophobicContact CE3-CB 3.84Å; W26-P244 HydrophobicContact CE3-CG 4.22Å; W26-P244 HydrophobicContact CH2-CB 4.05Å; W26-P244 HydrophobicContact CH2-CG 3.62Å; W26-P244 HydrophobicContact CZ2-CB 4.38Å; W26-P244 HydrophobicContact CZ2-CG 3.69Å; W26-P244 HydrophobicContact CZ3-CB 3.76Å; W26-P244 HydrophobicContact CZ3-CG 3.89Å
27	G	72.6	Confident	76.1	Confident	4 Å²	4	53.6 Å²	53.6	4%	0.041	30%	0.299	C	S	.	.	H	α-helix	trans	-65.8	-47.6	179.6	0	0	0	0	0	111.3	Q24 V29 L30 E31	Q24-G27 PolarHBondContact O-N 3.36Å; G27-V29 PolarHBondContact O-N 3.22Å; G27-L30 PolarHBondContact O-N 3.37Å; G27-E31 VanDerWaalsContact O-CB 3.24Å; G27-E31 WeakPolarHBondContact O-CB 3.44Å; G27-E31 PolarHBondContact O-N 2.73Å
28	I	79.5	Confident	77.5	Confident	71 Å²	71	53.2 Å²	53.2	36%	0.364	30%	0.3	S	S	.	.	H	α-helix	trans	-60.6	-44	178.5	-58.1	168.8	0	0	0	111.5	M22 E31 S32	M22-I28 HydrophobicContact SD-CD1 4.02Å; I28-E31 PolarHBondContact O-N 3.25Å; I28-S32 WeakPolarHBondContact O-CB 3.04Å; I28-S32 PolarHBondContact O-N 3.2Å; I28-S32 PolarHBondContact O-OG 3.26Å
29	V	84.5	Confident	79.2	Confident	82 Å²	82	55.5 Å²	55.5	50%	0.497	32%	0.316	S	S	.	.	H	α-helix	trans	-65.6	-43.5	179.2	173.7	0	0	0	0	110.8	A25 G27 S32 L33	A25-V29 VanDerWaalsContact O-CG2 3.31Å; A25-V29 WeakPolarHBondContact O-CG2 3.36Å; A25-V29 PolarHBondContact O-N 2.99Å; G27-V29 PolarHBondContact O-N 3.22Å; V29-S32 PolarHBondContact O-OG 3.35Å; V29-L33 HydrophobicContact CG1-CD1 3.98Å; V29-L33 WeakPolarHBondContact O-CB 3.34Å; V29-L33 VanDerWaalsContact O-CG 3.29Å; V29-L33 WeakPolarHBondContact O-CG 3.37Å; V29-L33 PolarHBondContact O-N 2.68Å
30	L	84.6	Confident	80.9	Confident	12 Å²	12	56.1 Å²	56.1	6%	0.063	32%	0.321	C	S	.	.	H	α-helix	trans	-69.4	-38.7	177.9	-71.4	176.6	0	0	0	112.7	W26 G27 L33 A34 A247 I248 V251	W26-L30 HydrophobicContact CE3-CD1 3.56Å; W26-L30 HydrophobicContact CZ3-CD1 3.84Å; W26-L30 WeakPolarHBondContact O-CB 3.39Å; W26-L30 WeakPolarHBondContact O-CG 3.44Å; W26-L30 PolarHBondContact O-N 2.92Å; G27-L30 PolarHBondContact O-N 3.37Å; L30-L33 PolarHBondContact O-N 3.19Å; L30-A34 WeakPolarHBondContact O-CB 2.96Å; L30-A34 PolarHBondContact O-N 2.64Å; L30-A247 HydrophobicContact CD1-CB 3.82Å; L30-I248 HydrophobicContact CD1-CG1 3.69Å; L30-I248 HydrophobicContact CD2-CB 4.46Å; L30-I248 HydrophobicContact CD2-CG1 3.87Å; L30-I248 HydrophobicContact CG-CG1 4.3Å; L30-V251 HydrophobicContact CD2-CB 4.22Å; L30-V251 HydrophobicContact CD2-CG1 4.47Å; L30-V251 HydrophobicContact CD2-CG2 4.07Å
31	E	86.6	Confident	82.6	Confident	60 Å²	60	54.1 Å²	54.1	28%	0.28	31%	0.308	S	S	.	.	H	α-helix	trans	-61.1	-48.7	176.6	-171.2	-172.9	158.4	0	0	110.9	G27 I28 A34 A35 F82 I85	G27-E31 VanDerWaalsContact O-CB 3.24Å; G27-E31 WeakPolarHBondContact O-CB 3.44Å; G27-E31 PolarHBondContact O-N 2.73Å; I28-E31 PolarHBondContact O-N 3.25Å; E31-A34 PolarHBondContact O-N 3.29Å; E31-A35 VanDerWaalsContact O-CB 3.3Å; E31-A35 WeakPolarHBondContact O-CB 3.39Å; E31-A35 PolarHBondContact O-N 3Å; E31-F82 HydrophobicContact CG-CD1 4.41Å; E31-F82 HydrophobicContact CG-CE1 3.72Å; E31-I85 HydrophobicContact CB-CD1 4.23Å
32	S	89.9	Confident	84.1	Confident	67 Å²	67	57.1 Å²	57.1	47%	0.469	32%	0.323	S	S	.	.	H	α-helix	trans	-63.5	-42.7	178	56	0	0	0	0	112.5	I28 V29 A35 A36	I28-S32 WeakPolarHBondContact O-CB 3.04Å; I28-S32 PolarHBondContact O-N 3.2Å; I28-S32 PolarHBondContact O-OG 3.26Å; V29-S32 PolarHBondContact O-OG 3.35Å; S32-A35 PolarHBondContact O-N 3.27Å; S32-A36 VanDerWaalsContact O-CB 3.29Å; S32-A36 WeakPolarHBondContact O-CB 3.23Å; S32-A36 PolarHBondContact O-N 3.07Å
33	L	92.8	Very high	85.8	Confident	71 Å²	71	57.5 Å²	57.5	37%	0.372	32%	0.322	S	S	.	.	H	α-helix	trans	-65.2	-38	175.4	-74.5	172.1	0	0	0	112.6	V29 L30 G37 V251 W255	V29-L33 HydrophobicContact CG1-CD1 3.98Å; V29-L33 WeakPolarHBondContact O-CB 3.34Å; V29-L33 VanDerWaalsContact O-CG 3.29Å; V29-L33 WeakPolarHBondContact O-CG 3.37Å; V29-L33 PolarHBondContact O-N 2.68Å; L30-L33 PolarHBondContact O-N 3.19Å; L33-G37 PolarHBondContact O-N 2.95Å; L33-V251 HydrophobicContact CB-CG1 3.69Å; L33-V251 HydrophobicContact CD1-CG1 4.26Å; L33-W255 PolarHBondContact O-NE1 3.18Å
34	A	91.9	Very high	87.5	Confident	0 Å²	0	51.5 Å²	51.5	0%	0	29%	0.294	C	S	.	.	H	α-helix	trans	-68.6	-46.2	175.9	0	0	0	0	0	111.5	L30 E31 A36 G37 V38 T81 F82 V251	L30-A34 WeakPolarHBondContact O-CB 2.96Å; L30-A34 PolarHBondContact O-N 2.64Å; E31-A34 PolarHBondContact O-N 3.29Å; A34-A36 VanDerWaalsContact C-N 3.35Å; A34-A36 PolarHBondContact O-N 3.01Å; A34-G37 CarbonylContact O-C 3.57Å; A34-G37 WeakPolarHBondContact O-CA 3.39Å; A34-G37 PolarHBondContact O-N 2.89Å; A34-G37 VanDerWaalsContact O-N 3.12Å; A34-V38 WeakPolarHBondContact O-CG2 3.42Å; A34-V38 PolarHBondContact O-N 2.69Å; A34-T81 WeakPolarHBondContact CB-OG1 3.36Å; A34-F82 HydrophobicContact CB-CE2 4.01Å; A34-F82 HydrophobicContact CB-CZ 4.13Å; A34-V251 HydrophobicContact CB-CG2 4.21Å
35	A	91.9	Very high	88.9	Confident	41 Å²	41	49.5 Å²	49.5	34%	0.339	29%	0.285	S	S	.	.	H	α-helix	trans	-60.3	-44.4	176.8	0	0	0	0	0	111.5	E31 S32 G37 V38 V39 F82	E31-A35 VanDerWaalsContact O-CB 3.3Å; E31-A35 WeakPolarHBondContact O-CB 3.39Å; E31-A35 PolarHBondContact O-N 3Å; S32-A35 PolarHBondContact O-N 3.27Å; A35-G37 VanDerWaalsContact C-N 3.33Å; A35-G37 PolarHBondContact O-N 3.11Å; A35-V38 PolarHBondContact O-N 3.25Å; A35-V39 WeakPolarHBondContact O-CG2 3.41Å; A35-V39 PolarHBondContact O-N 3.1Å; A35-F82 HydrophobicContact CB-CZ 4.23Å
36	A	94.7	Very high	89.9	Confident	42 Å²	42	49.8 Å²	49.8	35%	0.347	28%	0.282	S	S	.	.	H	α-helix	trans	-59.9	-44.4	172.9	0	0	0	0	0	111.4	S32 A34 V38 V39 V40 W255	S32-A36 VanDerWaalsContact O-CB 3.29Å; S32-A36 WeakPolarHBondContact O-CB 3.23Å; S32-A36 PolarHBondContact O-N 3.07Å; A34-A36 VanDerWaalsContact C-N 3.35Å; A34-A36 PolarHBondContact O-N 3.01Å; A36-V38 PolarHBondContact O-N 3.3Å; A36-V39 PolarHBondContact O-N 3.23Å; A36-V40 WeakPolarHBondContact O-CB 3.28Å; A36-V40 VanDerWaalsContact O-CG2 3.27Å; A36-V40 WeakPolarHBondContact O-CG2 3.44Å; A36-V40 PolarHBondContact O-N 3.07Å; A36-W255 HydrophobicContact CB-CH2 4.34Å; A36-W255 HydrophobicContact CB-CZ2 3.96Å
37	G	94.5	Very high	90.7	Very high	0 Å²	0	47.6 Å²	47.6	0%	0	28%	0.278	C	S	.	.	H	α-helix	trans	-56.9	-45.3	174	0	0	0	0	0	112.8	L33 A34 A35 V40 T41	L33-G37 PolarHBondContact O-N 2.95Å; A34-G37 CarbonylContact O-C 3.57Å; A34-G37 WeakPolarHBondContact O-CA 3.39Å; A34-G37 PolarHBondContact O-N 2.89Å; A34-G37 VanDerWaalsContact O-N 3.12Å; A35-G37 VanDerWaalsContact C-N 3.33Å; A35-G37 PolarHBondContact O-N 3.11Å; G37-V40 PolarHBondContact O-N 2.97Å; G37-T41 VanDerWaalsContact O-CB 3.31Å; G37-T41 WeakPolarHBondContact O-CB 3.48Å; G37-T41 PolarHBondContact O-N 3.21Å; G37-T41 PolarHBondContact O-OG1 3.35Å
38	V	95.5	Very high	91.5	Very high	32 Å²	32	47.5 Å²	47.5	19%	0.194	28%	0.276	C	S	.	.	H	α-helix	trans	-58.9	-51.2	175.6	169.4	0	0	0	0	111.2	A34 A35 A36 V40 T41 I42 L75 F78 F82	A34-V38 WeakPolarHBondContact O-CG2 3.42Å; A34-V38 PolarHBondContact O-N 2.69Å; A35-V38 PolarHBondContact O-N 3.25Å; A36-V38 PolarHBondContact O-N 3.3Å; V38-V40 PolarHBondContact O-N 3.13Å; V38-T41 PolarHBondContact O-N 2.91Å; V38-I42 HydrophobicContact CG1-CD1 3.74Å; V38-I42 HydrophobicContact CG1-CG1 4.45Å; V38-I42 WeakPolarHBondContact O-CG1 3.33Å; V38-I42 PolarHBondContact O-N 3.46Å; V38-L75 HydrophobicContact CB-CD1 4.38Å; V38-L75 HydrophobicContact CG1-CD1 3.92Å; V38-L75 HydrophobicContact CG2-CD1 4.36Å; V38-F78 HydrophobicContact CG2-CB 3.7Å; V38-F82 HydrophobicContact CG2-CE2 4.38Å
39	V	96.3	Very high	91.9	Very high	100 Å²	100	49.1 Å²	49.1	61%	0.606	28%	0.281	S	S	*	.	H	α-helix	trans	-60.3	-46.8	-179.4	172.7	0	0	0	0	111.1	A35 A36 T41 I42 F43	A35-V39 WeakPolarHBondContact O-CG2 3.41Å; A35-V39 PolarHBondContact O-N 3.1Å; A36-V39 PolarHBondContact O-N 3.23Å; V39-T41 VanDerWaalsContact C-N 3.33Å; V39-T41 PolarHBondContact O-N 3.34Å; V39-I42 PolarHBondContact O-N 2.9Å; V39-F43 WeakPolarHBondContact O-CB 3.37Å; V39-F43 PolarHBondContact O-N 3.35Å
40	V	95.8	Very high	91.9	Very high	54 Å²	54	50.6 Å²	50.6	33%	0.327	28%	0.281	S	S	.	.	H	α-helix	trans	-61.7	-43.3	177.3	172.7	0	0	0	0	110.7	A36 G37 V38 I42 F43 L44 W255 L258	A36-V40 WeakPolarHBondContact O-CB 3.28Å; A36-V40 VanDerWaalsContact O-CG2 3.27Å; A36-V40 WeakPolarHBondContact O-CG2 3.44Å; A36-V40 PolarHBondContact O-N 3.07Å; G37-V40 PolarHBondContact O-N 2.97Å; V38-V40 PolarHBondContact O-N 3.13Å; V40-I42 PolarHBondContact O-N 3.46Å; V40-F43 WeakPolarHBondContact O-CB 3.44Å; V40-F43 PolarHBondContact O-N 3.27Å; V40-L44 HydrophobicContact CG1-CD1 3.82Å; V40-L44 HydrophobicContact CG1-CG 4.34Å; V40-L44 VanDerWaalsContact O-CG 3.24Å; V40-L44 WeakPolarHBondContact O-CG 3.41Å; V40-L44 PolarHBondContact O-N 2.98Å; V40-W255 HydrophobicContact CG2-CH2 4.44Å; V40-L258 HydrophobicContact CB-CD1 4.36Å; V40-L258 HydrophobicContact CG1-CD1 3.94Å
41	T	95.6	Very high	91.8	Very high	0 Å²	0	51.8 Å²	51.8	0%	0	29%	0.285	C	S	.	.	H	α-helix	trans	-64.6	-43.1	-179.8	-51.3	0	0	0	0	111.4	G37 V38 V39 F43 L44 I45 L71 L75	G37-T41 VanDerWaalsContact O-CB 3.31Å; G37-T41 WeakPolarHBondContact O-CB 3.48Å; G37-T41 PolarHBondContact O-N 3.21Å; G37-T41 PolarHBondContact O-OG1 3.35Å; V38-T41 PolarHBondContact O-N 2.91Å; V39-T41 VanDerWaalsContact C-N 3.33Å; V39-T41 PolarHBondContact O-N 3.34Å; T41-F43 PolarHBondContact O-N 3.24Å; T41-L44 PolarHBondContact O-N 3.42Å; T41-I45 HydrophobicContact CG2-CD1 4.25Å; T41-I45 VanDerWaalsContact O-CG1 3.3Å; T41-I45 WeakPolarHBondContact O-CG1 3.27Å; T41-I45 PolarHBondContact O-N 2.83Å; T41-L71 HydrophobicContact CG2-CB 4.36Å; T41-L71 HydrophobicContact CG2-CD2 3.76Å; T41-L71 WeakPolarHBondContact CG2-O 3.47Å; T41-L75 HydrophobicContact CG2-CB 3.83Å; T41-L75 HydrophobicContact CG2-CD1 4.43Å
42	I	95.4	Very high	91.5	Very high	83 Å²	83	52 Å²	52	43%	0.426	29%	0.288	S	S	.	.	H	α-helix	trans	-60.7	-46	174.8	-68.9	168.9	0	0	0	110.5	V38 V39 V40 L44 I45 C46 L75	V38-I42 HydrophobicContact CG1-CD1 3.74Å; V38-I42 HydrophobicContact CG1-CG1 4.45Å; V38-I42 WeakPolarHBondContact O-CG1 3.33Å; V38-I42 PolarHBondContact O-N 3.46Å; V39-I42 PolarHBondContact O-N 2.9Å; V40-I42 PolarHBondContact O-N 3.46Å; I42-L44 VanDerWaalsContact C-N 3.31Å; I42-L44 PolarHBondContact O-N 3.16Å; I42-I45 PolarHBondContact O-N 3.24Å; I42-C46 PolarHBondContact O-N 3.18Å; I42-C46 PolarHBondContact O-SG 2.82Å; I42-C46 VanDerWaalsContact O-SG 3.37Å; I42-L75 HydrophobicContact CG1-CD1 4.11Å
43	F	94.9	Very high	90.8	Very high	142 Å²	142	54.2 Å²	54.2	62%	0.623	30%	0.302	S	S	*	.	H	α-helix	trans	-57.8	-43.8	176.4	176.5	-97.6	0	0	0	112	V39 V40 T41 C46 S47	V39-F43 WeakPolarHBondContact O-CB 3.37Å; V39-F43 PolarHBondContact O-N 3.35Å; V40-F43 WeakPolarHBondContact O-CB 3.44Å; V40-F43 PolarHBondContact O-N 3.27Å; T41-F43 PolarHBondContact O-N 3.24Å; F43-C46 PolarHBondContact O-N 3.2Å; F43-S47 WeakPolarHBondContact O-CB 3.44Å; F43-S47 PolarHBondContact O-N 3.26Å
44	L	93.6	Very high	90	Very high	16 Å²	16	57.8 Å²	57.8	8%	0.084	32%	0.315	C	S	.	.	H	α-helix	trans	-67.2	-37.2	177.7	-65.2	166.8	0	0	0	112.3	V40 T41 I42 S47 L48 L71 L258 I262 I266	V40-L44 HydrophobicContact CG1-CD1 3.82Å; V40-L44 HydrophobicContact CG1-CG 4.34Å; V40-L44 VanDerWaalsContact O-CG 3.24Å; V40-L44 WeakPolarHBondContact O-CG 3.41Å; V40-L44 PolarHBondContact O-N 2.98Å; T41-L44 PolarHBondContact O-N 3.42Å; I42-L44 VanDerWaalsContact C-N 3.31Å; I42-L44 PolarHBondContact O-N 3.16Å; L44-S47 PolarHBondContact O-N 2.92Å; L44-L48 WeakPolarHBondContact O-CB 3.46Å; L44-L48 PolarHBondContact O-N 3.38Å; L44-L71 HydrophobicContact CB-CD1 4.2Å; L44-L71 HydrophobicContact CB-CD2 3.98Å; L44-L71 HydrophobicContact CD1-CD2 4.3Å; L44-L258 HydrophobicContact CD1-CD2 3.87Å; L44-I262 HydrophobicContact CD1-CG2 3.94Å; L44-I266 HydrophobicContact CB-CD1 4.15Å; L44-I266 HydrophobicContact CD2-CD1 3.72Å; L44-I266 HydrophobicContact CG-CD1 4.42Å
45	I	93.3	Very high	89.1	Confident	22 Å²	22	59 Å²	59	11%	0.113	32%	0.322	C	S	.	.	H	α-helix	trans	-61.4	-49.3	172.8	-69.9	167.7	0	0	0	110.1	T41 I42 S47 L48 F49 F68 L71 L75	T41-I45 HydrophobicContact CG2-CD1 4.25Å; T41-I45 VanDerWaalsContact O-CG1 3.3Å; T41-I45 WeakPolarHBondContact O-CG1 3.27Å; T41-I45 PolarHBondContact O-N 2.83Å; I42-I45 PolarHBondContact O-N 3.24Å; I45-S47 VanDerWaalsContact C-N 3.32Å; I45-S47 PolarHBondContact O-N 3.43Å; I45-L48 WeakPolarHBondContact O-CB 3.24Å; I45-L48 PolarHBondContact O-N 3.33Å; I45-F49 HydrophobicContact CG2-CD2 3.82Å; I45-F49 HydrophobicContact CG2-CE2 3.54Å; I45-F49 WeakPolarHBondContact O-CD2 3.18Å; I45-F49 PolarHBondContact O-N 3.26Å; I45-F68 HydrophobicContact CG2-CE2 4.35Å; I45-L71 HydrophobicContact CD1-CB 4.14Å; I45-L71 HydrophobicContact CG1-CB 3.67Å; I45-L71 HydrophobicContact CG1-CD1 3.92Å; I45-L71 HydrophobicContact CG1-CG 4.28Å; I45-L75 HydrophobicContact CD1-CD2 4.23Å
46	C	91.9	Very high	87.7	Confident	76 Å²	76	66.2 Å²	66.2	51%	0.514	35%	0.349	S	S	.	.	H	α-helix	trans	-59.9	-42.7	176.3	-68.3	0	0	0	0	111.9	I42 F43 L48 F49 F50	I42-C46 PolarHBondContact O-N 3.18Å; I42-C46 PolarHBondContact O-SG 2.82Å; I42-C46 VanDerWaalsContact O-SG 3.37Å; F43-C46 PolarHBondContact O-N 3.2Å; C46-L48 VanDerWaalsContact C-N 3.3Å; C46-L48 PolarHBondContact O-N 3.42Å; C46-F49 PolarHBondContact O-N 3.08Å; C46-F50 PolarHBondContact O-N 3.43Å
47	S	89.4	Confident	86.6	Confident	25 Å²	25	66 Å²	66	18%	0.175	34%	0.341	C	S	.	.	H	α-helix	trans	-61	-40.4	175.9	-169.8	0	0	0	0	111.7	F43 L44 I45 F50 F51	F43-S47 WeakPolarHBondContact O-CB 3.44Å; F43-S47 PolarHBondContact O-N 3.26Å; L44-S47 PolarHBondContact O-N 2.92Å; I45-S47 VanDerWaalsContact C-N 3.32Å; I45-S47 PolarHBondContact O-N 3.43Å; S47-F50 WeakPolarHBondContact O-CB 3.41Å; S47-F50 PolarHBondContact O-N 3.28Å; S47-F51 WeakPolarHBondContact O-CD2 3.35Å; S47-F51 WeakPolarHBondContact O-CG 3.48Å; S47-F51 PolarHBondContact O-N 2.98Å; S47-F51 WeakPolarHBondContact OG-CE2 3.2Å
48	L	88.8	Confident	85.4	Confident	2 Å²	2	70 Å²	70	1%	0.01	36%	0.363	C	S	.	.	H	α-helix	trans	-64.5	-42.8	177	178.8	141.5	0	0	0	111.6	L44 I45 C46 F50 F51 I52 I64 Y67 F68 L71	L44-L48 WeakPolarHBondContact O-CB 3.46Å; L44-L48 PolarHBondContact O-N 3.38Å; I45-L48 WeakPolarHBondContact O-CB 3.24Å; I45-L48 PolarHBondContact O-N 3.33Å; C46-L48 VanDerWaalsContact C-N 3.3Å; C46-L48 PolarHBondContact O-N 3.42Å; L48-F50 VanDerWaalsContact C-N 3.31Å; L48-F50 PolarHBondContact O-N 2.93Å; L48-F51 PolarHBondContact O-N 3.29Å; L48-F51 VanDerWaalsContact O-N 3.13Å; L48-I52 HydrophobicContact CD2-CD1 4.21Å; L48-I52 WeakPolarHBondContact O-CG1 3.33Å; L48-I52 PolarHBondContact O-N 2.89Å; L48-I64 HydrophobicContact CD1-CG2 4.17Å; L48-I64 HydrophobicContact CD2-CG2 3.48Å; L48-I64 VanDerWaalsContact CD2-CG2 3.48Å; L48-I64 HydrophobicContact CG-CG2 3.84Å; L48-Y67 VanDerWaalsContact CD1-CB 3.47Å; L48-Y67 HydrophobicContact CD1-CD2 4.39Å; L48-Y67 HydrophobicContact CD1-CG 4.44Å; L48-F68 HydrophobicContact CD2-CB 4.14Å; L48-F68 HydrophobicContact CD2-CD2 4.47Å; L48-L71 HydrophobicContact CD1-CD1 4.37Å
49	F	87.9	Confident	84.1	Confident	104 Å²	104	69.5 Å²	69.5	46%	0.456	36%	0.361	S	S	.	.	H	α-helix	trans	-59.7	-40.8	172.7	-80.1	-69.4	0	0	0	112.5	I45 C46 F51 I52 F68	I45-F49 HydrophobicContact CG2-CD2 3.82Å; I45-F49 HydrophobicContact CG2-CE2 3.54Å; I45-F49 WeakPolarHBondContact O-CD2 3.18Å; I45-F49 PolarHBondContact O-N 3.26Å; C46-F49 PolarHBondContact O-N 3.08Å; F49-F51 VanDerWaalsContact C-N 3.32Å; F49-F51 PolarHBondContact O-N 2.67Å; F49-I52 HydrophobicContact CD1-CD1 3.89Å; F49-I52 HydrophobicContact CE1-CD1 4.37Å; F49-I52 WeakPolarHBondContact O-CB 3.44Å; F49-I52 PolarHBondContact O-N 3.42Å; F49-F68 HydrophobicContact CE2-CD2 4.19Å; F49-F68 AromaticContact CE2-CE2 3.8Å; F49-F68 HydrophobicContact CE2-CE2 3.8Å; F49-F68 HydrophobicContact CZ-CD2 4.05Å; F49-F68 AromaticContact CZ-CE2 3.6Å; F49-F68 HydrophobicContact CZ-CE2 3.6Å; F49-F68 HydrophobicContact CZ-CZ 4.4Å
50	F	85.7	Confident	83.2	Confident	114 Å²	114	65.5 Å²	65.5	50%	0.5	34%	0.335	S	S	.	.	H	α-helix	trans	-62.4	-39.6	174.2	179.6	-103.1	0	0	0	112.3	C46 S47 L48 C53 K54	C46-F50 PolarHBondContact O-N 3.43Å; S47-F50 WeakPolarHBondContact O-CB 3.41Å; S47-F50 PolarHBondContact O-N 3.28Å; L48-F50 VanDerWaalsContact C-N 3.31Å; L48-F50 PolarHBondContact O-N 2.93Å; F50-C53 PolarHBondContact O-N 2.61Å; F50-K54 HydrophobicContact CE1-CD 3.87Å; F50-K54 HydrophobicContact CZ-CD 3.96Å
51	F	80.8	Confident	82.5	Confident	36 Å²	36	68.4 Å²	68.4	16%	0.158	34%	0.34	C	S	.	.	H	α-helix	trans	-69	-30.2	177.1	-67.5	-50.8	0	0	0	113.4	S47 L48 F49 C53 K54 V55 I266 T270	S47-F51 WeakPolarHBondContact O-CD2 3.35Å; S47-F51 WeakPolarHBondContact O-CG 3.48Å; S47-F51 PolarHBondContact O-N 2.98Å; S47-F51 WeakPolarHBondContact OG-CE2 3.2Å; L48-F51 PolarHBondContact O-N 3.29Å; L48-F51 VanDerWaalsContact O-N 3.13Å; F49-F51 VanDerWaalsContact C-N 3.32Å; F49-F51 PolarHBondContact O-N 2.67Å; F51-C53 PolarHBondContact O-N 3.5Å; F51-K54 PolarHBondContact O-N 3.28Å; F51-V55 HydrophobicContact CB-CG2 4.33Å; F51-V55 VanDerWaalsContact O-CG2 3.23Å; F51-V55 WeakPolarHBondContact O-CG2 3.46Å; F51-V55 PolarHBondContact O-N 2.93Å; F51-I266 HydrophobicContact CD2-CG2 4.47Å; F51-I266 HydrophobicContact CE2-CG2 3.84Å; F51-T270 HydrophobicContact CD1-CG2 4.22Å; F51-T270 HydrophobicContact CE1-CG2 3.42Å; F51-T270 VanDerWaalsContact CE1-CG2 3.42Å; F51-T270 HydrophobicContact CE2-CG2 3.8Å; F51-T270 HydrophobicContact CZ-CG2 3.18Å
52	I	80.4	Confident	81.8	Confident	65 Å²	65	70.8 Å²	70.8	33%	0.333	35%	0.351	S	S	.	.	H	α-helix	trans	-52.5	-42.3	173.2	-69.3	170.9	0	0	0	111.1	L48 F49 K54 I64	L48-I52 HydrophobicContact CD2-CD1 4.21Å; L48-I52 WeakPolarHBondContact O-CG1 3.33Å; L48-I52 PolarHBondContact O-N 2.89Å; F49-I52 HydrophobicContact CD1-CD1 3.89Å; F49-I52 HydrophobicContact CE1-CD1 4.37Å; F49-I52 WeakPolarHBondContact O-CB 3.44Å; F49-I52 PolarHBondContact O-N 3.42Å; I52-K54 VanDerWaalsContact C-N 3.31Å; I52-K54 PolarHBondContact O-N 3.46Å; I52-I64 HydrophobicContact CB-CD1 4.41Å; I52-I64 HydrophobicContact CD1-CG2 3.68Å; I52-I64 HydrophobicContact CG1-CD1 3.65Å; I52-I64 HydrophobicContact CG1-CG2 3.53Å
53	C	76.1	Confident	81.3	Confident	114 Å²	114	67.6 Å²	67.6	77%	0.77	34%	0.335	S	S	*	.	H	α-helix	trans	-73.3	-21.7	-179.1	-61.1	0	0	0	0	113.5	F50 F51	F50-C53 PolarHBondContact O-N 2.61Å; F51-C53 PolarHBondContact O-N 3.5Å
54	K	75.6	Confident	81	Confident	146 Å²	146	61.2 Å²	61.2	64%	0.635	31%	0.307	S	S	*	.	H	α-helix	trans	-104.6	-21.8	-173.9	-80.8	-165.1	164.4	170	0	115.1	F50 F51 I52 Q56	F50-K54 HydrophobicContact CE1-CD 3.87Å; F50-K54 HydrophobicContact CZ-CD 3.96Å; F51-K54 PolarHBondContact O-N 3.28Å; I52-K54 VanDerWaalsContact C-N 3.31Å; I52-K54 PolarHBondContact O-N 3.46Å; K54-Q56 PolarHBondContact O-N 3.46Å
55	V	73.9	Confident	80.8	Confident	25 Å²	25	61.1 Å²	61.1	15%	0.152	31%	0.309	C	S	.	.			trans	-77	110.5	-177.2	173	0	0	0	0	110	F51 D57 K60 R61	F51-V55 HydrophobicContact CB-CG2 4.33Å; F51-V55 VanDerWaalsContact O-CG2 3.23Å; F51-V55 WeakPolarHBondContact O-CG2 3.46Å; F51-V55 PolarHBondContact O-N 2.93Å; V55-D57 HydrophobicContact CG1-CB 4.29Å; V55-D57 WeakPolarHBondContact CG1-O 3.46Å; V55-K60 HydrophobicContact CG1-CB 3.87Å; V55-R61 HydrophobicContact CG1-CB 4.5Å
56	Q	62.2	Low	80.7	Confident	193 Å²	193	60.1 Å²	60.1	90%	0.902	30%	0.304	S	S	*	.			trans	-76.9	-22.2	172	-94.6	174.5	-11.2	0	0	113.3	K54 N58	K54-Q56 PolarHBondContact O-N 3.46Å; Q56-N58 PolarHBondContact O-N 2.96Å
57	D	70.8	Confident	80.8	Confident	36 Å²	36	56.7 Å²	56.7	19%	0.193	28%	0.28	C	S	.	.			trans	-80.1	111.2	-178.4	-178.7	-1.2	0	0	0	111.7	V55 S59 K60 R61 L273 Y278	V55-D57 HydrophobicContact CG1-CB 4.29Å; V55-D57 WeakPolarHBondContact CG1-O 3.46Å; D57-S59 PolarHBondContact O-N 3.4Å; D57-S59 WeakPolarHBondContact OD1-CB 3.42Å; D57-S59 PolarHBondContact OD1-N 3.39Å; D57-K60 HydrophobicContact CB-CB 4.19Å; D57-K60 HydrophobicContact CB-CD 4.26Å; D57-K60 HydrophobicContact CB-CG 4.3Å; D57-K60 PolarHBondContact O-N 3.43Å; D57-K60 WeakPolarHBondContact OD2-CG 3.47Å; D57-R61 WeakPolarHBondContact O-CB 3.29Å; D57-R61 PolarHBondContact O-N 3.28Å; D57-L273 HydrophobicContact CB-CD1 4.02Å; D57-L273 WeakPolarHBondContact OD2-CD1 3.39Å; D57-Y278 PolarHBondContact OD2-OH 3.46Å
58	N	69.7	Low	81	Confident	86 Å²	86	58.4 Å²	58.4	46%	0.46	28%	0.284	S	S	.	.	H	α-helix	trans	-59.1	-32.2	177.9	-70.7	-44.1	0	0	0	112.8	Q56 R61 H62	Q56-N58 PolarHBondContact O-N 2.96Å; N58-R61 PolarHBondContact O-N 3.43Å; N58-R61 PolarHBondContact OD1-NH1 3.35Å; N58-R61 PolarHBondContact OD1-NH2 2.92Å; N58-H62 PolarHBondContact O-CD2 3.39Å; N58-H62 VanDerWaalsContact O-CD2 3.24Å; N58-H62 VanDerWaalsContact O-CG 3.25Å; N58-H62 PolarHBondContact O-N 3.26Å; N58-H62 VanDerWaalsContact O-N 3.15Å
59	S	69	Low	81.3	Confident	21 Å²	21	61.2 Å²	61.2	15%	0.147	30%	0.297	C	S	.	.	H	α-helix	trans	-68.5	-45.1	178.7	-176	0	0	0	0	111.5	D57 R61 H62	D57-S59 PolarHBondContact O-N 3.4Å; D57-S59 WeakPolarHBondContact OD1-CB 3.42Å; D57-S59 PolarHBondContact OD1-N 3.39Å; S59-R61 VanDerWaalsContact C-N 3.3Å; S59-H62 PolarHBondContact O-N 2.85Å
60	K	76.2	Confident	81.7	Confident	15 Å²	15	56.3 Å²	56.3	7%	0.065	28%	0.275	C	S	.	.	H	α-helix	trans	-65.4	-37.2	174.5	-73.4	-179.6	-177	-163.5	0	111	V55 D57 H62 M63 L269 A271	V55-K60 HydrophobicContact CG1-CB 3.87Å; D57-K60 HydrophobicContact CB-CB 4.19Å; D57-K60 HydrophobicContact CB-CD 4.26Å; D57-K60 HydrophobicContact CB-CG 4.3Å; D57-K60 PolarHBondContact O-N 3.43Å; D57-K60 WeakPolarHBondContact OD2-CG 3.47Å; K60-H62 VanDerWaalsContact C-N 3.28Å; K60-H62 PolarHBondContact O-N 3.38Å; K60-M63 PolarHBondContact O-N 3.01Å; K60-M63 VanDerWaalsContact O-N 3.14Å; K60-L269 HydrophobicContact CB-CD2 3.96Å; K60-L269 HydrophobicContact CG-CD2 4.35Å; K60-A271 PolarHBondContact NZ-O 3.27Å
61	R	80.4	Confident	82.2	Confident	115 Å²	115	50.9 Å²	50.9	43%	0.434	25%	0.251	S	S	.	.	H	α-helix	trans	-61.2	-34.2	177.5	-163.3	176	70.4	-159.5	-1.7	112.9	V55 D57 N58 S59 M63 I64	V55-R61 HydrophobicContact CG1-CB 4.5Å; D57-R61 WeakPolarHBondContact O-CB 3.29Å; D57-R61 PolarHBondContact O-N 3.28Å; N58-R61 PolarHBondContact O-N 3.43Å; N58-R61 PolarHBondContact OD1-NH1 3.35Å; N58-R61 PolarHBondContact OD1-NH2 2.92Å; S59-R61 VanDerWaalsContact C-N 3.3Å; R61-M63 VanDerWaalsContact C-N 3.31Å; R61-M63 PolarHBondContact O-N 3.21Å; R61-I64 HydrophobicContact CB-CD1 4.44Å; R61-I64 HydrophobicContact CG-CD1 4.06Å; R61-I64 VanDerWaalsContact O-CB 3.29Å; R61-I64 WeakPolarHBondContact O-CB 3.31Å; R61-I64 WeakPolarHBondContact O-CG1 3.32Å; R61-I64 PolarHBondContact O-N 3Å
62	H	81.1	Confident	82.9	Confident	50 Å²	50	53.2 Å²	53.2	23%	0.231	27%	0.265	C	S	.	.	H	α-helix	trans	-66.7	-30.2	176.9	-62.9	164.4	0	0	0	113.2	N58 S59 K60 I64 W130	N58-H62 PolarHBondContact O-CD2 3.39Å; N58-H62 VanDerWaalsContact O-CD2 3.24Å; N58-H62 VanDerWaalsContact O-CG 3.25Å; N58-H62 PolarHBondContact O-N 3.26Å; N58-H62 VanDerWaalsContact O-N 3.15Å; S59-H62 PolarHBondContact O-N 2.85Å; K60-H62 VanDerWaalsContact C-N 3.28Å; K60-H62 PolarHBondContact O-N 3.38Å; H62-I64 VanDerWaalsContact C-N 3.28Å; H62-I64 PolarHBondContact O-N 3.17Å; H62-W130 HydrophobicContact CB-CB 4.08Å; H62-W130 VanDerWaalsContact O-CD1 3.25Å
63	M	86.6	Confident	83.6	Confident	16 Å²	16	50.2 Å²	50.2	8%	0.079	25%	0.25	C	C	.	.	H	α-helix	trans	-74.4	-20.4	178.9	-62.6	-60.5	112.4	0	0	112.7	K60 R61 A65 I66 Y67 N117 L133	K60-M63 PolarHBondContact O-N 3.01Å; K60-M63 VanDerWaalsContact O-N 3.14Å; R61-M63 VanDerWaalsContact C-N 3.31Å; R61-M63 PolarHBondContact O-N 3.21Å; M63-A65 VanDerWaalsContact C-N 3.26Å; M63-A65 PolarHBondContact O-N 3.37Å; M63-I66 HydrophobicContact CE-CD1 4.48Å; M63-I66 WeakPolarHBondContact O-CB 3.32Å; M63-I66 PolarHBondContact O-N 3.02Å; M63-I66 HydrophobicContact SD-CD1 3.88Å; M63-Y67 HydrophobicContact CB-CD2 4.37Å; M63-Y67 HydrophobicContact CB-CE2 3.62Å; M63-Y67 VanDerWaalsContact O-CD2 3.3Å; M63-Y67 WeakPolarHBondContact O-CD2 3.3Å; M63-Y67 PolarHBondContact O-N 3.14Å; M63-N117 WeakPolarHBondContact CE-ND2 3.31Å; M63-N117 PolarHBondContact SD-ND2 3.43Å; M63-L133 HydrophobicContact CE-CD1 3.31Å
64	I	87.8	Confident	84.5	Confident	9 Å²	9	44.8 Å²	44.8	5%	0.046	21%	0.213	C	C	.	.	H	α-helix	trans	-53.9	-41.5	-178.6	-66.4	-176.7	0	0	0	112	L48 I52 R61 H62 I66 Y67 F68	L48-I64 HydrophobicContact CD1-CG2 4.17Å; L48-I64 HydrophobicContact CD2-CG2 3.48Å; L48-I64 VanDerWaalsContact CD2-CG2 3.48Å; L48-I64 HydrophobicContact CG-CG2 3.84Å; I52-I64 HydrophobicContact CB-CD1 4.41Å; I52-I64 HydrophobicContact CD1-CG2 3.68Å; I52-I64 HydrophobicContact CG1-CD1 3.65Å; I52-I64 HydrophobicContact CG1-CG2 3.53Å; R61-I64 HydrophobicContact CB-CD1 4.44Å; R61-I64 HydrophobicContact CG-CD1 4.06Å; R61-I64 VanDerWaalsContact O-CB 3.29Å; R61-I64 WeakPolarHBondContact O-CB 3.31Å; R61-I64 WeakPolarHBondContact O-CG1 3.32Å; R61-I64 PolarHBondContact O-N 3Å; H62-I64 VanDerWaalsContact C-N 3.28Å; H62-I64 PolarHBondContact O-N 3.17Å; I64-I66 VanDerWaalsContact C-N 3.32Å; I64-I66 PolarHBondContact O-N 2.89Å; I64-Y67 PolarHBondContact O-N 3.33Å; I64-F68 WeakPolarHBondContact O-CB 3.47Å; I64-F68 PolarHBondContact O-N 3.15Å
65	A	88.8	Confident	85.5	Confident	13 Å²	13	39.9 Å²	39.9	11%	0.107	19%	0.194	C	C	.	.	H	α-helix	trans	-66.8	-35.3	179.5	0	0	0	0	0	112.8	M63 Y67 F68 F69 W130	M63-A65 VanDerWaalsContact C-N 3.26Å; M63-A65 PolarHBondContact O-N 3.37Å; A65-Y67 VanDerWaalsContact C-N 3.31Å; A65-Y67 PolarHBondContact O-N 3.27Å; A65-F68 PolarHBondContact O-N 3.35Å; A65-F69 WeakPolarHBondContact O-CD2 3.38Å; A65-F69 PolarHBondContact O-N 3.3Å; A65-W130 HydrophobicContact CB-CZ2 4.13Å
66	I	92.6	Very high	86.5	Confident	2 Å²	2	39.7 Å²	39.7	1%	0.01	20%	0.197	C	C	.	.	H	α-helix	trans	-60.2	-47.6	175.7	-53.6	-172.5	0	0	0	109.2	M63 I64 F68 F69 F70 C110 T113 H114 L133 I137	M63-I66 HydrophobicContact CE-CD1 4.48Å; M63-I66 WeakPolarHBondContact O-CB 3.32Å; M63-I66 PolarHBondContact O-N 3.02Å; M63-I66 HydrophobicContact SD-CD1 3.88Å; I64-I66 VanDerWaalsContact C-N 3.32Å; I64-I66 PolarHBondContact O-N 2.89Å; I66-F68 VanDerWaalsContact C-N 3.34Å; I66-F68 PolarHBondContact O-N 3.4Å; I66-F69 PolarHBondContact O-N 2.96Å; I66-F70 VanDerWaalsContact O-CB 3.25Å; I66-F70 WeakPolarHBondContact O-CB 3.33Å; I66-F70 PolarHBondContact O-N 2.96Å; I66-C110 HydrophobicContact CG2-CB 3.91Å; I66-T113 HydrophobicContact CD1-CG2 4.29Å; I66-H114 HydrophobicContact CD1-CB 4.46Å; I66-H114 HydrophobicContact CG2-CB 4.31Å; I66-L133 HydrophobicContact CD1-CB 4.36Å; I66-L133 HydrophobicContact CD1-CD1 4.23Å; I66-L133 HydrophobicContact CD1-CD2 4.16Å; I66-L133 HydrophobicContact CD1-CG 4.48Å; I66-I137 HydrophobicContact CB-CD1 4.35Å; I66-I137 HydrophobicContact CG1-CD1 4.01Å; I66-I137 HydrophobicContact CG2-CD1 4.36Å
67	Y	93.3	Very high	88	Confident	4 Å²	4	30.5 Å²	30.5	2%	0.016	15%	0.154	C	C	.	.	H	α-helix	trans	-65.1	-37.6	178.2	-54.1	-45.6	0	0	0	112.1	L48 M63 I64 A65 F70 L71 I262 E265 L269	L48-Y67 VanDerWaalsContact CD1-CB 3.47Å; L48-Y67 HydrophobicContact CD1-CD2 4.39Å; L48-Y67 HydrophobicContact CD1-CG 4.44Å; M63-Y67 HydrophobicContact CB-CD2 4.37Å; M63-Y67 HydrophobicContact CB-CE2 3.62Å; M63-Y67 VanDerWaalsContact O-CD2 3.3Å; M63-Y67 WeakPolarHBondContact O-CD2 3.3Å; M63-Y67 PolarHBondContact O-N 3.14Å; I64-Y67 PolarHBondContact O-N 3.33Å; A65-Y67 VanDerWaalsContact C-N 3.31Å; A65-Y67 PolarHBondContact O-N 3.27Å; Y67-F70 PolarHBondContact O-N 3.27Å; Y67-L71 VanDerWaalsContact O-CB 3.27Å; Y67-L71 WeakPolarHBondContact O-CB 3.44Å; Y67-L71 VanDerWaalsContact O-CG 3.28Å; Y67-L71 WeakPolarHBondContact O-CG 3.21Å; Y67-L71 PolarHBondContact O-N 3.24Å; Y67-I262 HydrophobicContact CD1-CD1 4.33Å; Y67-E265 HydrophobicContact CD1-CB 4.47Å; Y67-E265 HydrophobicContact CE1-CB 3.75Å; Y67-E265 HydrophobicContact CE1-CG 3.98Å; Y67-E265 PolarHBondContact OH-OE2 3.09Å; Y67-L269 HydrophobicContact CD2-CD1 3.77Å; Y67-L269 HydrophobicContact CE2-CD1 3.65Å; Y67-L269 HydrophobicContact CE2-CD2 4.16Å; Y67-L269 HydrophobicContact CE2-CG 4.07Å
68	F	93.6	Very high	89.1	Confident	61 Å²	61	28.8 Å²	28.8	27%	0.268	15%	0.145	S	C	.	.	H	α-helix	trans	-61.9	-51.6	175.7	176	-100	0	0	0	112.2	I45 L48 F49 I64 A65 I66 F70 L71 L72	I45-F68 HydrophobicContact CG2-CE2 4.35Å; L48-F68 HydrophobicContact CD2-CB 4.14Å; L48-F68 HydrophobicContact CD2-CD2 4.47Å; F49-F68 HydrophobicContact CE2-CD2 4.19Å; F49-F68 AromaticContact CE2-CE2 3.8Å; F49-F68 HydrophobicContact CE2-CE2 3.8Å; F49-F68 HydrophobicContact CZ-CD2 4.05Å; F49-F68 AromaticContact CZ-CE2 3.6Å; F49-F68 HydrophobicContact CZ-CE2 3.6Å; F49-F68 HydrophobicContact CZ-CZ 4.4Å; I64-F68 WeakPolarHBondContact O-CB 3.47Å; I64-F68 PolarHBondContact O-N 3.15Å; A65-F68 PolarHBondContact O-N 3.35Å; I66-F68 VanDerWaalsContact C-N 3.34Å; I66-F68 PolarHBondContact O-N 3.4Å; F68-F70 VanDerWaalsContact C-N 3.31Å; F68-F70 PolarHBondContact O-N 3.26Å; F68-L71 PolarHBondContact O-N 2.87Å; F68-L72 WeakPolarHBondContact O-CB 3.3Å; F68-L72 PolarHBondContact O-N 2.69Å
69	F	94.9	Very high	90	Very high	61 Å²	61	26.4 Å²	26.4	27%	0.268	14%	0.14	S	C	.	.	H	α-helix	trans	-64.3	-37.5	177.9	-78	-70.5	0	0	0	112.1	A65 I66 L72 G73 L134	A65-F69 WeakPolarHBondContact O-CD2 3.38Å; A65-F69 PolarHBondContact O-N 3.3Å; I66-F69 PolarHBondContact O-N 2.96Å; F69-L72 PolarHBondContact O-N 2.87Å; F69-G73 PolarHBondContact O-N 3Å; F69-L134 HydrophobicContact CD2-CD1 4.2Å; F69-L134 HydrophobicContact CE2-CD1 3.32Å; F69-L134 HydrophobicContact CZ-CD1 3.81Å
70	F	96.1	Very high	91	Very high	0 Å²	0	25.6 Å²	25.6	0%	0	14%	0.135	C	C	.	.	H	α-helix	trans	-64.3	-44.9	175.1	-175.4	-85.1	0	0	0	112.2	I66 Y67 F68 L72 G73 T74 C107 C110 L111 F257 Y261 I262	I66-F70 VanDerWaalsContact O-CB 3.25Å; I66-F70 WeakPolarHBondContact O-CB 3.33Å; I66-F70 PolarHBondContact O-N 2.96Å; Y67-F70 PolarHBondContact O-N 3.27Å; F68-F70 VanDerWaalsContact C-N 3.31Å; F68-F70 PolarHBondContact O-N 3.26Å; F70-L72 VanDerWaalsContact C-N 3.32Å; F70-L72 PolarHBondContact O-N 3.45Å; F70-G73 PolarHBondContact O-N 2.71Å; F70-T74 WeakPolarHBondContact CE1-OG1 3.29Å; F70-T74 WeakPolarHBondContact O-CB 2.81Å; F70-T74 PolarHBondContact O-N 3.17Å; F70-T74 PolarHBondContact O-OG1 2.9Å; F70-C107 HydrophobicContact CD2-CB 4.24Å; F70-C107 HydrophobicContact CE2-CB 4.04Å; F70-C110 HydrophobicContact CB-CB 3.98Å; F70-C110 HydrophobicContact CD2-CB 3.98Å; F70-C110 HydrophobicContact CG-CB 4.49Å; F70-L111 HydrophobicContact CD2-CD2 4.4Å; F70-L111 HydrophobicContact CD2-CG 4.17Å; F70-L111 HydrophobicContact CE2-CD1 3.88Å; F70-L111 HydrophobicContact CE2-CD2 3.85Å; F70-L111 HydrophobicContact CE2-CG 3.63Å; F70-L111 HydrophobicContact CZ-CD2 4.44Å; F70-F257 HydrophobicContact CE1-CB 3.73Å; F70-F257 HydrophobicContact CE1-CD2 4.45Å; F70-F257 HydrophobicContact CE1-CG 4.19Å; F70-F257 HydrophobicContact CE2-CD2 4.34Å; F70-F257 HydrophobicContact CE2-CG 4.34Å; F70-F257 HydrophobicContact CZ-CB 3.51Å; F70-F257 HydrophobicContact CZ-CD1 4Å; F70-F257 AromaticContact CZ-CD2 3.77Å; F70-F257 HydrophobicContact CZ-CD2 3.77Å; F70-F257 HydrophobicContact CZ-CE2 4.49Å; F70-F257 AromaticContact CZ-CG 3.49Å; F70-F257 HydrophobicContact CZ-CG 3.49Å; F70-F257 VanDerWaalsContact CZ-CG 3.49Å; F70-Y261 HydrophobicContact CB-CE1 4.46Å; F70-Y261 AromaticContact CD1-CD1 3.87Å; F70-Y261 HydrophobicContact CD1-CD1 3.87Å; F70-Y261 AromaticContact CD1-CE1 3.79Å; F70-Y261 HydrophobicContact CD1-CE1 3.79Å; F70-Y261 HydrophobicContact CD2-CD1 4.23Å; F70-Y261 AromaticContact CD2-CE1 3.81Å; F70-Y261 HydrophobicContact CD2-CE1 3.81Å; F70-Y261 AromaticContact CE1-CD1 3.45Å; F70-Y261 HydrophobicContact CE1-CD1 3.45Å; F70-Y261 VanDerWaalsContact CE1-CD1 3.45Å; F70-Y261 AromaticContact CE1-CE1 3.86Å; F70-Y261 HydrophobicContact CE1-CE1 3.86Å; F70-Y261 AromaticContact CE2-CD1 3.88Å; F70-Y261 HydrophobicContact CE2-CD1 3.88Å; F70-Y261 AromaticContact CE2-CE1 3.9Å; F70-Y261 HydrophobicContact CE2-CE1 3.9Å; F70-Y261 HydrophobicContact CG-CD1 4.21Å; F70-Y261 AromaticContact CG-CE1 3.74Å; F70-Y261 HydrophobicContact CG-CE1 3.74Å; F70-Y261 AromaticContact CZ-CD1 3.43Å; F70-Y261 HydrophobicContact CZ-CD1 3.43Å; F70-Y261 VanDerWaalsContact CZ-CD1 3.43Å; F70-Y261 AromaticContact CZ-CE1 3.89Å; F70-Y261 HydrophobicContact CZ-CE1 3.89Å; F70-Y261 HydrophobicContact CZ-CG 4.44Å; F70-I262 HydrophobicContact CD1-CD1 3.48Å; F70-I262 VanDerWaalsContact CD1-CD1 3.48Å; F70-I262 HydrophobicContact CD1-CG1 3.59Å; F70-I262 HydrophobicContact CE1-CD1 3.95Å; F70-I262 HydrophobicContact CE1-CG1 3.58Å; F70-I262 HydrophobicContact CG-CD1 4.3Å
71	L	95.9	Very high	91.5	Very high	0 Å²	0	24.9 Å²	24.9	0%	0	13%	0.132	C	C	.	.	H	α-helix	trans	-63.5	-38.4	175.6	-80.5	168.6	0	0	0	111.5	T41 L44 I45 L48 Y67 F68 T74 L75 L258 I262	T41-L71 HydrophobicContact CG2-CB 4.36Å; T41-L71 HydrophobicContact CG2-CD2 3.76Å; T41-L71 WeakPolarHBondContact CG2-O 3.47Å; L44-L71 HydrophobicContact CB-CD1 4.2Å; L44-L71 HydrophobicContact CB-CD2 3.98Å; L44-L71 HydrophobicContact CD1-CD2 4.3Å; I45-L71 HydrophobicContact CD1-CB 4.14Å; I45-L71 HydrophobicContact CG1-CB 3.67Å; I45-L71 HydrophobicContact CG1-CD1 3.92Å; I45-L71 HydrophobicContact CG1-CG 4.28Å; L48-L71 HydrophobicContact CD1-CD1 4.37Å; Y67-L71 VanDerWaalsContact O-CB 3.27Å; Y67-L71 WeakPolarHBondContact O-CB 3.44Å; Y67-L71 VanDerWaalsContact O-CG 3.28Å; Y67-L71 WeakPolarHBondContact O-CG 3.21Å; Y67-L71 PolarHBondContact O-N 3.24Å; F68-L71 PolarHBondContact O-N 2.87Å; L71-T74 PolarHBondContact O-N 3.29Å; L71-L75 VanDerWaalsContact O-CB 3.29Å; L71-L75 WeakPolarHBondContact O-CB 3.41Å; L71-L75 PolarHBondContact O-N 3.26Å; L71-L258 HydrophobicContact CD2-CD2 4.14Å; L71-I262 HydrophobicContact CD2-CG1 4.24Å; L71-I262 HydrophobicContact CD2-CG2 4.08Å; L71-I262 HydrophobicContact CG-CD1 4.24Å; L71-I262 HydrophobicContact CG-CG1 4.5Å
72	L	95.7	Very high	91.5	Very high	85 Å²	85	22 Å²	22	45%	0.445	12%	0.122	S	C	.	.	H	α-helix	trans	-64	-42.9	174.7	-174.4	63.7	0	0	0	111.8	F68 F69 F70 L75 G76	F68-L72 WeakPolarHBondContact O-CB 3.3Å; F68-L72 PolarHBondContact O-N 2.69Å; F69-L72 PolarHBondContact O-N 2.87Å; F70-L72 VanDerWaalsContact C-N 3.32Å; F70-L72 PolarHBondContact O-N 3.45Å; L72-L75 PolarHBondContact O-N 2.9Å; L72-G76 PolarHBondContact O-N 3.27Å
73	G	95.4	Very high	91.2	Very high	2 Å²	2	20.6 Å²	20.6	2%	0.021	12%	0.119	C	C	.	.	H	α-helix	trans	-61.7	-43.1	173.1	0	0	0	0	0	112.2	F69 F70 G76 I77 C107	F69-G73 PolarHBondContact O-N 3Å; F70-G73 PolarHBondContact O-N 2.71Å; G73-G76 CarbonylContact O-C 3.59Å; G73-G76 PolarHBondContact O-N 3.31Å; G73-I77 WeakPolarHBondContact O-CG1 3.2Å; G73-I77 PolarHBondContact O-N 3.41Å; G73-C107 VanDerWaalsContact C-SG 3.58Å
74	T	95.4	Very high	90.5	Very high	0 Å²	0	20.1 Å²	20.1	0%	0	12%	0.117	C	C	.	.	H	α-helix	trans	-67.7	-39.3	178.7	-53.8	0	0	0	0	112	F70 L71 G76 I77 F78 F257 L258	F70-T74 WeakPolarHBondContact CE1-OG1 3.29Å; F70-T74 WeakPolarHBondContact O-CB 2.81Å; F70-T74 PolarHBondContact O-N 3.17Å; F70-T74 PolarHBondContact O-OG1 2.9Å; L71-T74 PolarHBondContact O-N 3.29Å; T74-G76 VanDerWaalsContact C-N 3.29Å; T74-G76 PolarHBondContact O-N 2.6Å; T74-I77 WeakPolarHBondContact O-CB 3.4Å; T74-I77 PolarHBondContact O-N 3.48Å; T74-I77 VanDerWaalsContact O-N 3.13Å; T74-F78 HydrophobicContact CG2-CD2 4.03Å; T74-F78 HydrophobicContact CG2-CE2 3.64Å; T74-F78 VanDerWaalsContact O-CD2 3.27Å; T74-F78 WeakPolarHBondContact O-CD2 3.48Å; T74-F78 PolarHBondContact O-N 2.92Å; T74-F257 HydrophobicContact CG2-CB 4.34Å; T74-L258 HydrophobicContact CG2-CD2 3.98Å; T74-L258 HydrophobicContact CG2-CG 4.15Å
75	L	96	Very high	89.5	Confident	43 Å²	43	19.8 Å²	19.8	23%	0.225	12%	0.115	C	C	.	.	H	α-helix	trans	-59.2	-44.2	171.9	-179.9	64.7	0	0	0	110.3	V38 T41 I42 I45 L71 L72 I77 F78 G79	V38-L75 HydrophobicContact CB-CD1 4.38Å; V38-L75 HydrophobicContact CG1-CD1 3.92Å; V38-L75 HydrophobicContact CG2-CD1 4.36Å; T41-L75 HydrophobicContact CG2-CB 3.83Å; T41-L75 HydrophobicContact CG2-CD1 4.43Å; I42-L75 HydrophobicContact CG1-CD1 4.11Å; I45-L75 HydrophobicContact CD1-CD2 4.23Å; L71-L75 VanDerWaalsContact O-CB 3.29Å; L71-L75 WeakPolarHBondContact O-CB 3.41Å; L71-L75 PolarHBondContact O-N 3.26Å; L72-L75 PolarHBondContact O-N 2.9Å; L75-I77 VanDerWaalsContact C-N 3.34Å; L75-I77 PolarHBondContact O-N 3.41Å; L75-F78 PolarHBondContact O-N 2.9Å; L75-G79 PolarHBondContact O-N 3.34Å
76	G	93.9	Very high	88.4	Confident	22 Å²	22	20.9 Å²	20.9	23%	0.227	12%	0.119	C	C	.	.	H	α-helix	trans	-62.8	-37.5	174.1	0	0	0	0	0	112.8	L72 G73 T74 G79 L80 L103	L72-G76 PolarHBondContact O-N 3.27Å; G73-G76 CarbonylContact O-C 3.59Å; G73-G76 PolarHBondContact O-N 3.31Å; T74-G76 VanDerWaalsContact C-N 3.29Å; T74-G76 PolarHBondContact O-N 2.6Å; G76-G79 CarbonylContact O-C 3.58Å; G76-G79 PolarHBondContact O-N 3.22Å; G76-L80 VanDerWaalsContact O-CB 3.27Å; G76-L80 WeakPolarHBondContact O-CB 3.29Å; G76-L80 PolarHBondContact O-N 3.49Å; G76-L103 WeakPolarHBondContact O-CD1 3.37Å
77	I	94.4	Very high	86.8	Confident	0 Å²	0	25.7 Å²	25.7	0%	0	14%	0.139	C	C	.	.	H	α-helix	trans	-61.5	-48.5	175.9	-72.9	168	0	0	0	110.6	G73 T74 L75 G79 L80 T81 L103 F104 L250 F257	G73-I77 WeakPolarHBondContact O-CG1 3.2Å; G73-I77 PolarHBondContact O-N 3.41Å; T74-I77 WeakPolarHBondContact O-CB 3.4Å; T74-I77 PolarHBondContact O-N 3.48Å; T74-I77 VanDerWaalsContact O-N 3.13Å; L75-I77 VanDerWaalsContact C-N 3.34Å; L75-I77 PolarHBondContact O-N 3.41Å; I77-G79 VanDerWaalsContact C-N 3.3Å; I77-G79 PolarHBondContact O-N 3.14Å; I77-L80 PolarHBondContact O-N 3.21Å; I77-T81 PolarHBondContact O-N 2.88Å; I77-L103 HydrophobicContact CG1-CB 4.09Å; I77-F104 HydrophobicContact CD1-CD1 3.85Å; I77-F104 HydrophobicContact CD1-CE1 3.64Å; I77-F104 HydrophobicContact CD1-CG 4.45Å; I77-F104 HydrophobicContact CD1-CZ 4.12Å; I77-F104 HydrophobicContact CG1-CE1 4.43Å; I77-F104 HydrophobicContact CG1-CZ 4.46Å; I77-L250 HydrophobicContact CG2-CB 4.18Å; I77-L250 HydrophobicContact CG2-CD2 3.87Å; I77-L250 WeakPolarHBondContact CG2-O 3.33Å; I77-F257 HydrophobicContact CD1-CD2 4.15Å; I77-F257 HydrophobicContact CD1-CE2 3.86Å
78	F	93.4	Very high	85.1	Confident	0 Å²	0	29 Å²	29	0%	0	16%	0.157	C	C	.	.	H	α-helix	trans	-69	-26.3	174.4	-66.9	-61.5	0	0	0	113.1	V38 T74 L75 T81 F82 W255 L258	V38-F78 HydrophobicContact CG2-CB 3.7Å; T74-F78 HydrophobicContact CG2-CD2 4.03Å; T74-F78 HydrophobicContact CG2-CE2 3.64Å; T74-F78 VanDerWaalsContact O-CD2 3.27Å; T74-F78 WeakPolarHBondContact O-CD2 3.48Å; T74-F78 PolarHBondContact O-N 2.92Å; L75-F78 PolarHBondContact O-N 2.9Å; F78-T81 PolarHBondContact O-OG1 3.06Å; F78-F82 VanDerWaalsContact O-CD2 3.32Å; F78-F82 WeakPolarHBondContact O-CD2 3.45Å; F78-F82 WeakPolarHBondContact O-CE2 3.44Å; F78-W255 AromaticContact CE1-CD1 3.85Å; F78-W255 HydrophobicContact CE1-CG 4.37Å; F78-W255 AromaticContact CE1-NE1 3.87Å; F78-W255 HydrophobicContact CZ-CD2 4.45Å; F78-W255 HydrophobicContact CZ-CG 4.29Å; F78-L258 HydrophobicContact CE2-CD1 3.59Å; F78-L258 HydrophobicContact CE2-CG 4.06Å; F78-L258 HydrophobicContact CZ-CD1 3.89Å; F78-L258 HydrophobicContact CZ-CG 4.41Å
79	G	90.1	Very high	83.6	Confident	35 Å²	35	29.7 Å²	29.7	36%	0.361	16%	0.163	S	C	.	.	H	α-helix	trans	-70.5	-39.5	170.7	0	0	0	0	0	111.9	L75 G76 I77 T81 F82	L75-G79 PolarHBondContact O-N 3.34Å; G76-G79 CarbonylContact O-C 3.58Å; G76-G79 PolarHBondContact O-N 3.22Å; I77-G79 VanDerWaalsContact C-N 3.3Å; I77-G79 PolarHBondContact O-N 3.14Å; G79-T81 VanDerWaalsContact C-N 3.27Å; G79-T81 PolarHBondContact O-N 3.25Å; G79-F82 PolarHBondContact O-N 3.19Å
80	L	89.1	Confident	82.1	Confident	5 Å²	5	30.5 Å²	30.5	3%	0.026	17%	0.171	C	C	.	.	H	α-helix	trans	-67.1	-28	-177.3	-171.3	65.3	0	0	0	112.1	G76 I77 F82 A83 F84 L99 F100 L103 L250	G76-L80 VanDerWaalsContact O-CB 3.27Å; G76-L80 WeakPolarHBondContact O-CB 3.29Å; G76-L80 PolarHBondContact O-N 3.49Å; I77-L80 PolarHBondContact O-N 3.21Å; L80-F82 PolarHBondContact O-N 2.9Å; L80-A83 HydrophobicContact CD1-CB 4.08Å; L80-A83 WeakPolarHBondContact O-CA 3.44Å; L80-A83 VanDerWaalsContact O-CB 3.31Å; L80-A83 WeakPolarHBondContact O-CB 3.44Å; L80-A83 PolarHBondContact O-N 3.41Å; L80-F84 HydrophobicContact CD1-CE2 4.29Å; L80-F84 HydrophobicContact CD2-CE2 3.88Å; L80-F84 HydrophobicContact CG-CD2 4.01Å; L80-F84 HydrophobicContact CG-CE2 3.74Å; L80-F84 WeakPolarHBondContact O-CD2 3.33Å; L80-F84 PolarHBondContact O-N 3.07Å; L80-F84 VanDerWaalsContact O-N 3.15Å; L80-L99 HydrophobicContact CD1-CB 3.74Å; L80-L99 HydrophobicContact CD1-CD1 4.09Å; L80-L99 HydrophobicContact CD2-CB 4.29Å; L80-F100 VanDerWaalsContact CD2-CA 3.48Å; L80-F100 HydrophobicContact CD2-CB 3.8Å; L80-F100 HydrophobicContact CD2-CD2 3.97Å; L80-F100 HydrophobicContact CD2-CG 4.27Å; L80-L103 HydrophobicContact CB-CD1 4.16Å; L80-L103 HydrophobicContact CD2-CD1 4.14Å; L80-L250 HydrophobicContact CB-CD1 4.48Å; L80-L250 HydrophobicContact CD2-CD1 4.23Å; L80-L250 HydrophobicContact CD2-CD2 4.19Å; L80-L250 HydrophobicContact CG-CD1 4.25Å
81	T	86.4	Confident	80.7	Confident	0 Å²	0	34.8 Å²	34.8	0%	0	20%	0.201	C	C	.	.	H	α-helix	trans	-58.6	-37.1	175.6	56.5	0	0	0	0	111.7	A34 I77 F78 G79 A83 F84 I85 L250 V251	A34-T81 WeakPolarHBondContact CB-OG1 3.36Å; I77-T81 PolarHBondContact O-N 2.88Å; F78-T81 PolarHBondContact O-OG1 3.06Å; G79-T81 VanDerWaalsContact C-N 3.27Å; G79-T81 PolarHBondContact O-N 3.25Å; T81-A83 VanDerWaalsContact C-N 3.29Å; T81-A83 PolarHBondContact O-N 3.11Å; T81-F84 PolarHBondContact O-N 3.32Å; T81-F84 VanDerWaalsContact O-N 3.11Å; T81-I85 WeakPolarHBondContact O-CG1 3.3Å; T81-I85 PolarHBondContact O-N 3.24Å; T81-L250 HydrophobicContact CG2-CB 3.45Å; T81-L250 VanDerWaalsContact CG2-CB 3.45Å; T81-L250 HydrophobicContact CG2-CD1 4.08Å; T81-L250 HydrophobicContact CG2-CG 4.4Å; T81-V251 HydrophobicContact CG2-CG2 3.49Å; T81-V251 VanDerWaalsContact CG2-CG2 3.49Å
82	F	80.5	Confident	79.5	Confident	55 Å²	55	36.1 Å²	36.1	24%	0.241	21%	0.208	C	C	.	.	H	α-helix	trans	-64.1	-35.6	174.1	-65.2	-83.1	0	0	0	111.9	L19 E31 A34 A35 V38 F78 G79 L80 F84 I85 I86	L19-F82 HydrophobicContact CD2-CD1 4.33Å; E31-F82 HydrophobicContact CG-CD1 4.41Å; E31-F82 HydrophobicContact CG-CE1 3.72Å; A34-F82 HydrophobicContact CB-CE2 4.01Å; A34-F82 HydrophobicContact CB-CZ 4.13Å; A35-F82 HydrophobicContact CB-CZ 4.23Å; V38-F82 HydrophobicContact CG2-CE2 4.38Å; F78-F82 VanDerWaalsContact O-CD2 3.32Å; F78-F82 WeakPolarHBondContact O-CD2 3.45Å; F78-F82 WeakPolarHBondContact O-CE2 3.44Å; G79-F82 PolarHBondContact O-N 3.19Å; L80-F82 PolarHBondContact O-N 2.9Å; F82-F84 VanDerWaalsContact C-N 3.25Å; F82-F84 PolarHBondContact O-N 2.82Å; F82-I85 PolarHBondContact O-N 3.19Å; F82-I86 WeakPolarHBondContact O-CD1 3.45Å; F82-I86 VanDerWaalsContact O-CG1 3.29Å; F82-I86 WeakPolarHBondContact O-CG1 3.49Å; F82-I86 PolarHBondContact O-N 3.5Å
83	A	75.8	Confident	78.5	Confident	19 Å²	19	34.3 Å²	34.3	16%	0.157	20%	0.196	C	C	.	.	H	α-helix	trans	-67.5	-26	175.1	0	0	0	0	0	112.7	L80 T81 T92 R96	L80-A83 HydrophobicContact CD1-CB 4.08Å; L80-A83 WeakPolarHBondContact O-CA 3.44Å; L80-A83 VanDerWaalsContact O-CB 3.31Å; L80-A83 WeakPolarHBondContact O-CB 3.44Å; L80-A83 PolarHBondContact O-N 3.41Å; T81-A83 VanDerWaalsContact C-N 3.29Å; T81-A83 PolarHBondContact O-N 3.11Å; A83-T92 HydrophobicContact CB-CG2 4.43Å; A83-T92 WeakPolarHBondContact O-CG2 3.31Å; A83-R96 PolarHBondContact O-NE 3.09Å; A83-R96 PolarHBondContact O-NH2 2.99Å
84	F	71.6	Confident	77.7	Confident	7 Å²	7	35.3 Å²	35.3	3%	0.031	20%	0.202	C	C	.	.	H	α-helix	trans	-82.6	-26.9	171.3	-79	-80.9	0	0	0	113.2	L80 T81 F82 R96 F100 L246 A247 L250	L80-F84 HydrophobicContact CD1-CE2 4.29Å; L80-F84 HydrophobicContact CD2-CE2 3.88Å; L80-F84 HydrophobicContact CG-CD2 4.01Å; L80-F84 HydrophobicContact CG-CE2 3.74Å; L80-F84 WeakPolarHBondContact O-CD2 3.33Å; L80-F84 PolarHBondContact O-N 3.07Å; L80-F84 VanDerWaalsContact O-N 3.15Å; T81-F84 PolarHBondContact O-N 3.32Å; T81-F84 VanDerWaalsContact O-N 3.11Å; F82-F84 VanDerWaalsContact C-N 3.25Å; F82-F84 PolarHBondContact O-N 2.82Å; F84-R96 HydrophobicContact CD1-CG 4.32Å; F84-R96 HydrophobicContact CD2-CG 4.41Å; F84-R96 HydrophobicContact CE1-CB 4.22Å; F84-R96 HydrophobicContact CE1-CG 3.97Å; F84-R96 HydrophobicContact CE2-CB 4.34Å; F84-R96 HydrophobicContact CE2-CG 4.07Å; F84-R96 HydrophobicContact CZ-CB 3.84Å; F84-R96 HydrophobicContact CZ-CG 3.85Å; F84-F100 AromaticContact CE2-CD2 3.92Å; F84-F100 HydrophobicContact CE2-CD2 3.92Å; F84-F100 HydrophobicContact CZ-CD2 4.01Å; F84-L246 HydrophobicContact CD1-CB 4.01Å; F84-L246 HydrophobicContact CD1-CD1 4.16Å; F84-L246 HydrophobicContact CE1-CB 3.92Å; F84-L246 HydrophobicContact CE1-CD1 3.47Å; F84-L246 VanDerWaalsContact CE1-CD1 3.47Å; F84-L246 HydrophobicContact CE1-CG 4.33Å; F84-L246 HydrophobicContact CZ-CB 4.35Å; F84-L246 HydrophobicContact CZ-CD1 4.12Å; F84-A247 HydrophobicContact CB-CB 4.26Å; F84-L250 HydrophobicContact CD2-CD1 3.45Å; F84-L250 VanDerWaalsContact CD2-CD1 3.45Å; F84-L250 HydrophobicContact CE2-CD1 3.64Å; F84-L250 HydrophobicContact CG-CD1 4.4Å
85	I	67.3	Low	77	Confident	2 Å²	2	38.1 Å²	38.1	1%	0.01	22%	0.22	C	C	.	.	H	α-helix	trans	-75.6	-40.3	174.7	-67.4	162.1	0	0	0	111.5	L18 L19 E31 T81 F82	L18-I85 WeakPolarHBondContact CB-O 3.35Å; L19-I85 HydrophobicContact CD2-CG2 3.76Å; L19-I85 HydrophobicContact CG-CG2 4.08Å; E31-I85 HydrophobicContact CB-CD1 4.23Å; T81-I85 WeakPolarHBondContact O-CG1 3.3Å; T81-I85 PolarHBondContact O-N 3.24Å; F82-I85 PolarHBondContact O-N 3.19Å
86	I	64.9	Low	76.5	Confident	36 Å²	36	36.4 Å²	36.4	19%	0.185	21%	0.21	C	C	.	.	S	Bend	trans	-66	141.1	175.8	-65.8	159.5	0	0	0	109.7	Y16 L19 F82 R96	Y16-I86 HydrophobicContact CD1-CD1 4.27Å; Y16-I86 HydrophobicContact CD1-CG1 4.09Å; Y16-I86 HydrophobicContact CD1-CG2 4.09Å; Y16-I86 HydrophobicContact CE1-CD1 4.08Å; Y16-I86 HydrophobicContact CE1-CG1 4.33Å; Y16-I86 HydrophobicContact CE1-CG2 4.08Å; L19-I86 HydrophobicContact CD1-CD1 4.22Å; L19-I86 HydrophobicContact CD1-CG1 3.56Å; L19-I86 HydrophobicContact CG-CG1 4.19Å; F82-I86 WeakPolarHBondContact O-CD1 3.45Å; F82-I86 VanDerWaalsContact O-CG1 3.29Å; F82-I86 WeakPolarHBondContact O-CG1 3.49Å; F82-I86 PolarHBondContact O-N 3.5Å; I86-R96 PolarHBondContact O-NH2 3.27Å
87	K	59	Low	76	Confident	103 Å²	103	36.4 Å²	36.4	45%	0.448	20%	0.204	S	C	.	.			trans	-58	143.5	179.4	-157	179.7	-175.2	-179.7	0	111.2	D15 L18 N89	D15-K87 HydrophobicContact CB-CB 4.17Å; D15-K87 WeakPolarHBondContact O-CB 2.9Å; D15-K87 PolarHBondContact O-N 2.89Å; L18-K87 HydrophobicContact CD1-CB 4.14Å; L18-K87 HydrophobicContact CD1-CG 4.38Å; K87-N89 PolarHBondContact O-N 3.41Å; K87-N89 VanDerWaalsContact O-N 3.15Å
88	L	56.6	Low	75.7	Confident	73 Å²	73	39 Å²	39	38%	0.382	22%	0.216	S	C	.	.			trans	-61.7	114.7	-177.5	-166.3	76.8	0	0	0	111.1	R93 R96	L88-R93 HydrophobicContact CD1-CB 3.89Å; L88-R93 HydrophobicContact CD1-CG 4.26Å; L88-R93 HydrophobicContact CG-CB 4.36Å; L88-R96 VanDerWaalsContact CD1-NH1 3.33Å
89	N	63.1	Low	75.6	Confident	75 Å²	75	41.9 Å²	41.9	40%	0.401	23%	0.23	S	C	.	.			trans	-113.4	164.5	167.5	-157.4	-23.8	0	0	0	108.9	D15 K87 S91 T92 R93	D15-N89 PolarHBondContact OD2-ND2 2.91Å; K87-N89 PolarHBondContact O-N 3.41Å; K87-N89 VanDerWaalsContact O-N 3.15Å; N89-S91 VanDerWaalsContact C-N 3.28Å; N89-S91 PolarHBondContact O-N 3.43Å; N89-T92 WeakPolarHBondContact CB-OG1 3.28Å; N89-T92 PolarHBondContact N-OG1 3.47Å; N89-T92 WeakPolarHBondContact O-CB 3.3Å; N89-T92 PolarHBondContact O-N 3.45Å; N89-R93 PolarHBondContact O-N 3.12Å
90	D	63.5	Low	75.7	Confident	79 Å²	79	40.2 Å²	40.2	42%	0.422	21%	0.213	S	C	.	.	H	α-helix	trans	-57	-41.1	-174.3	-75.8	-6.6	0	0	0	112.1	L164	D90-L164 HydrophobicContact CB-CD2 4.47Å; D90-L164 WeakPolarHBondContact OD1-CD2 3.27Å
91	S	66.3	Low	75.9	Confident	90 Å²	90	40 Å²	40	63%	0.629	21%	0.212	S	C	*	.	H	α-helix	trans	-67.9	-41.9	174	-57.4	0	0	0	0	111.9	N89 R93 S94 T95	N89-S91 VanDerWaalsContact C-N 3.28Å; N89-S91 PolarHBondContact O-N 3.43Å; S91-R93 VanDerWaalsContact C-N 3.32Å; S91-R93 PolarHBondContact O-N 2.97Å; S91-S94 PolarHBondContact O-N 3.45Å; S91-T95 PolarHBondContact O-N 2.93Å; S91-T95 PolarHBondContact O-OG1 2.82Å
92	T	71.4	Confident	76.3	Confident	27 Å²	27	40.9 Å²	40.9	17%	0.166	22%	0.217	C	C	.	.	H	α-helix	trans	-64.5	-36.5	-178.3	-34	0	0	0	0	111.7	A83 N89 T95 R96	A83-T92 HydrophobicContact CB-CG2 4.43Å; A83-T92 WeakPolarHBondContact O-CG2 3.31Å; N89-T92 WeakPolarHBondContact CB-OG1 3.28Å; N89-T92 PolarHBondContact N-OG1 3.47Å; N89-T92 WeakPolarHBondContact O-CB 3.3Å; N89-T92 PolarHBondContact O-N 3.45Å; T92-T95 PolarHBondContact O-N 3.46Å; T92-R96 WeakPolarHBondContact O-CB 3.37Å; T92-R96 WeakPolarHBondContact O-CG 3.18Å; T92-R96 PolarHBondContact O-N 2.85Å
93	R	74.8	Confident	77	Confident	47 Å²	47	39.3 Å²	39.3	18%	0.177	21%	0.212	C	C	.	.	H	α-helix	trans	-60.9	-49.1	177.1	-171	-177.1	-61.8	-170.3	3.2	111.7	L88 N89 S91 R96 F97 F163 L164	L88-R93 HydrophobicContact CD1-CB 3.89Å; L88-R93 HydrophobicContact CD1-CG 4.26Å; L88-R93 HydrophobicContact CG-CB 4.36Å; N89-R93 PolarHBondContact O-N 3.12Å; S91-R93 VanDerWaalsContact C-N 3.32Å; S91-R93 PolarHBondContact O-N 2.97Å; R93-R96 PolarHBondContact O-N 3.3Å; R93-F97 WeakPolarHBondContact O-CD2 2.85Å; R93-F97 PolarHBondContact O-N 3.48Å; R93-F163 HydrophobicContact CG-CE1 4.24Å; R93-F163 HydrophobicContact CG-CZ 4.12Å; R93-F163 PolarHBondContact NH1-O 3.31Å; R93-L164 VanDerWaalsContact NH1-C 3.33Å; R93-L164 VanDerWaalsContact NH1-CA 3.34Å; R93-L164 PolarHBondContact NH1-O 3.29Å
94	S	78.6	Confident	78	Confident	23 Å²	23	38.5 Å²	38.5	16%	0.161	20%	0.204	C	C	.	.	H	α-helix	trans	-62.4	-46	178.3	-178.4	0	0	0	0	111.5	S91 R96 F97 F98 L152	S91-S94 PolarHBondContact O-N 3.45Å; S94-R96 VanDerWaalsContact C-N 3.35Å; S94-R96 PolarHBondContact O-N 3.04Å; S94-F97 PolarHBondContact O-N 3.01Å; S94-F98 PolarHBondContact O-N 3.27Å; S94-F98 VanDerWaalsContact O-N 3.13Å; S94-L152 WeakPolarHBondContact OG-CD1 3.5Å; S94-L152 WeakPolarHBondContact OG-CD2 3.47Å
95	T	81.1	Confident	79.2	Confident	59 Å²	59	38.2 Å²	38.2	36%	0.362	20%	0.203	S	C	.	.	H	α-helix	trans	-60.9	-40.2	179.1	-58.9	0	0	0	0	112.6	S91 T92 L99	S91-T95 PolarHBondContact O-N 2.93Å; S91-T95 PolarHBondContact O-OG1 2.82Å; T92-T95 PolarHBondContact O-N 3.46Å; T95-L99 HydrophobicContact CG2-CD1 3.39Å; T95-L99 HydrophobicContact CG2-CG 4.06Å; T95-L99 VanDerWaalsContact O-CB 3.29Å; T95-L99 WeakPolarHBondContact O-CB 3.47Å; T95-L99 PolarHBondContact O-N 2.9Å
96	R	85.1	Confident	80.6	Confident	7 Å²	7	39.3 Å²	39.3	3%	0.026	21%	0.21	C	C	.	.	H	α-helix	trans	-60.8	-49.5	177.2	-75.5	170.8	-172.1	-166.6	7.1	112	A83 F84 I86 L88 T92 R93 S94 F98 F100 D243	A83-R96 PolarHBondContact O-NE 3.09Å; A83-R96 PolarHBondContact O-NH2 2.99Å; F84-R96 HydrophobicContact CD1-CG 4.32Å; F84-R96 HydrophobicContact CD2-CG 4.41Å; F84-R96 HydrophobicContact CE1-CB 4.22Å; F84-R96 HydrophobicContact CE1-CG 3.97Å; F84-R96 HydrophobicContact CE2-CB 4.34Å; F84-R96 HydrophobicContact CE2-CG 4.07Å; F84-R96 HydrophobicContact CZ-CB 3.84Å; F84-R96 HydrophobicContact CZ-CG 3.85Å; I86-R96 PolarHBondContact O-NH2 3.27Å; L88-R96 VanDerWaalsContact CD1-NH1 3.33Å; T92-R96 WeakPolarHBondContact O-CB 3.37Å; T92-R96 WeakPolarHBondContact O-CG 3.18Å; T92-R96 PolarHBondContact O-N 2.85Å; R93-R96 PolarHBondContact O-N 3.3Å; S94-R96 VanDerWaalsContact C-N 3.35Å; S94-R96 PolarHBondContact O-N 3.04Å; R96-F98 VanDerWaalsContact C-N 3.35Å; R96-F98 PolarHBondContact O-N 3.06Å; R96-F100 WeakPolarHBondContact O-CB 3.29Å; R96-F100 PolarHBondContact O-N 2.93Å; R96-F100 VanDerWaalsContact O-N 3.13Å; R96-D243 IonicContact CZ-OD1 3.94Å; R96-D243 IonicContact CZ-OD2 3.84Å; R96-D243 IonicContact NH1-OD1 2.81Å; R96-D243 PolarHBondContact NH1-OD1 2.93Å; R96-D243 IonicContact NH1-OD2 2.9Å; R96-D243 PolarHBondContact NH1-OD2 3.42Å; R96-D243 IonicContact NH2-OD2 3.88Å
97	F	83.5	Confident	82.1	Confident	23 Å²	23	37.6 Å²	37.6	10%	0.101	20%	0.201	C	C	.	.	H	α-helix	trans	-62.4	-43.1	-178.7	-86.9	-111.2	0	0	0	112	R93 S94 Y151 T171 F175 L178	R93-F97 WeakPolarHBondContact O-CD2 2.85Å; R93-F97 PolarHBondContact O-N 3.48Å; S94-F97 PolarHBondContact O-N 3.01Å; F97-Y151 HydrophobicContact CD1-CE1 4.06Å; F97-T171 HydrophobicContact CE2-CG2 4.08Å; F97-T171 HydrophobicContact CZ-CG2 3.5Å; F97-T171 VanDerWaalsContact CZ-CG2 3.5Å; F97-F175 HydrophobicContact CD1-CB 4.49Å; F97-F175 AromaticContact CD1-CD2 3.81Å; F97-F175 HydrophobicContact CD1-CD2 3.81Å; F97-F175 HydrophobicContact CD2-CD2 4.25Å; F97-F175 HydrophobicContact CE1-CB 3.65Å; F97-F175 AromaticContact CE1-CD2 3.7Å; F97-F175 HydrophobicContact CE1-CD2 3.7Å; F97-F175 HydrophobicContact CE1-CG 4.17Å; F97-F175 HydrophobicContact CE2-CD2 4.15Å; F97-F175 HydrophobicContact CG-CD2 4.07Å; F97-F175 HydrophobicContact CZ-CB 3.81Å; F97-F175 AromaticContact CZ-CD2 3.85Å; F97-F175 HydrophobicContact CZ-CD2 3.85Å; F97-F175 HydrophobicContact CZ-CG 4.22Å; F97-L178 HydrophobicContact CD1-CD1 3.7Å; F97-L178 HydrophobicContact CE1-CD1 4.3Å
98	F	88.5	Confident	83.9	Confident	55 Å²	55	32.7 Å²	32.7	24%	0.241	18%	0.18	C	C	.	.	H	α-helix	trans	-71.5	-56	-179.7	178.9	-102.8	0	0	0	113.2	S94 R96 F100 V102 I149 L152	S94-F98 PolarHBondContact O-N 3.27Å; S94-F98 VanDerWaalsContact O-N 3.13Å; R96-F98 VanDerWaalsContact C-N 3.35Å; R96-F98 PolarHBondContact O-N 3.06Å; F98-F100 VanDerWaalsContact C-N 3.34Å; F98-F100 PolarHBondContact O-N 2.62Å; F98-V102 HydrophobicContact CD2-CG2 4.27Å; F98-V102 HydrophobicContact CE1-CG2 4.38Å; F98-V102 HydrophobicContact CE2-CG2 3.95Å; F98-V102 HydrophobicContact CZ-CG2 4.01Å; F98-V102 VanDerWaalsContact O-CG2 3.31Å; F98-V102 WeakPolarHBondContact O-CG2 3.33Å; F98-V102 PolarHBondContact O-N 2.91Å; F98-I149 HydrophobicContact CE2-CG1 3.89Å; F98-L152 HydrophobicContact CB-CD1 3.63Å; F98-L152 HydrophobicContact CD2-CD1 4.06Å; F98-L152 HydrophobicContact CG-CD1 4.11Å
99	L	90.4	Very high	85.9	Confident	59 Å²	59	29.2 Å²	29.2	31%	0.309	16%	0.162	S	C	.	.	H	α-helix	trans	-67.2	-35.4	-173	-74.9	178.3	0	0	0	112	L80 T95 G101 V102 L103	L80-L99 HydrophobicContact CD1-CB 3.74Å; L80-L99 HydrophobicContact CD1-CD1 4.09Å; L80-L99 HydrophobicContact CD2-CB 4.29Å; T95-L99 HydrophobicContact CG2-CD1 3.39Å; T95-L99 HydrophobicContact CG2-CG 4.06Å; T95-L99 VanDerWaalsContact O-CB 3.29Å; T95-L99 WeakPolarHBondContact O-CB 3.47Å; T95-L99 PolarHBondContact O-N 2.9Å; L99-G101 PolarHBondContact O-N 3.22Å; L99-V102 PolarHBondContact O-N 3.5Å; L99-L103 HydrophobicContact CB-CD1 4.09Å; L99-L103 VanDerWaalsContact O-CB 3.23Å; L99-L103 WeakPolarHBondContact O-CB 3.39Å; L99-L103 WeakPolarHBondContact O-CD1 3.2Å; L99-L103 WeakPolarHBondContact O-CG 3.32Å; L99-L103 PolarHBondContact O-N 2.84Å
100	F	92.2	Very high	87.4	Confident	1 Å²	1	25.7 Å²	25.7	0%	0.004	14%	0.143	C	C	.	.	H	α-helix	trans	-57.9	-52.9	-179.2	-167.8	-78.4	0	0	0	111.3	L80 F84 R96 F98 F104 F175 L179 W222 W225 L246 L250	L80-F100 VanDerWaalsContact CD2-CA 3.48Å; L80-F100 HydrophobicContact CD2-CB 3.8Å; L80-F100 HydrophobicContact CD2-CD2 3.97Å; L80-F100 HydrophobicContact CD2-CG 4.27Å; F84-F100 AromaticContact CE2-CD2 3.92Å; F84-F100 HydrophobicContact CE2-CD2 3.92Å; F84-F100 HydrophobicContact CZ-CD2 4.01Å; R96-F100 WeakPolarHBondContact O-CB 3.29Å; R96-F100 PolarHBondContact O-N 2.93Å; R96-F100 VanDerWaalsContact O-N 3.13Å; F98-F100 VanDerWaalsContact C-N 3.34Å; F98-F100 PolarHBondContact O-N 2.62Å; F100-F104 AromaticContact CD1-CD2 3.83Å; F100-F104 HydrophobicContact CD1-CD2 3.83Å; F100-F104 HydrophobicContact CD1-CE2 4.08Å; F100-F104 HydrophobicContact CD2-CE2 4.36Å; F100-F104 AromaticContact CE1-CD2 3.68Å; F100-F104 HydrophobicContact CE1-CD2 3.68Å; F100-F104 AromaticContact CE1-CE2 3.63Å; F100-F104 HydrophobicContact CE1-CE2 3.63Å; F100-F104 AromaticContact CE2-CE2 3.97Å; F100-F104 HydrophobicContact CE2-CE2 3.97Å; F100-F104 HydrophobicContact CG-CD2 4.38Å; F100-F104 HydrophobicContact CG-CE2 4.43Å; F100-F104 HydrophobicContact CZ-CD2 4.14Å; F100-F104 AromaticContact CZ-CE2 3.59Å; F100-F104 HydrophobicContact CZ-CE2 3.59Å; F100-F104 VanDerWaalsContact O-CD2 3.28Å; F100-F104 WeakPolarHBondContact O-CD2 3.49Å; F100-F104 PolarHBondContact O-N 3.2Å; F100-F175 HydrophobicContact CB-CE2 4.1Å; F100-F175 HydrophobicContact CB-CZ 4.01Å; F100-F175 HydrophobicContact CD1-CE1 4.36Å; F100-F175 HydrophobicContact CD1-CE2 4.34Å; F100-F175 AromaticContact CD1-CZ 3.62Å; F100-F175 HydrophobicContact CD1-CZ 3.62Å; F100-F175 AromaticContact CD2-CZ 3.83Å; F100-F175 HydrophobicContact CD2-CZ 3.83Å; F100-F175 HydrophobicContact CE1-CE1 4.26Å; F100-F175 AromaticContact CE1-CZ 3.94Å; F100-F175 HydrophobicContact CE1-CZ 3.94Å; F100-F175 HydrophobicContact CE2-CZ 4.12Å; F100-F175 HydrophobicContact CG-CE2 4.16Å; F100-F175 AromaticContact CG-CZ 3.55Å; F100-F175 HydrophobicContact CG-CZ 3.55Å; F100-F175 HydrophobicContact CZ-CE1 4.38Å; F100-F175 HydrophobicContact CZ-CZ 4.17Å; F100-L179 HydrophobicContact CD1-CD1 3.78Å; F100-L179 HydrophobicContact CD1-CD2 3.74Å; F100-L179 HydrophobicContact CD1-CG 4.42Å; F100-L179 HydrophobicContact CE1-CD1 3.59Å; F100-L179 HydrophobicContact CE1-CD2 4.24Å; F100-W222 HydrophobicContact CE1-CH2 4.02Å; F100-W222 HydrophobicContact CE1-CZ2 4.25Å; F100-W225 HydrophobicContact CE1-CH2 4.15Å; F100-W225 AromaticContact CE1-CZ2 3.89Å; F100-W225 HydrophobicContact CE1-CZ2 3.89Å; F100-W225 HydrophobicContact CZ-CH2 4.15Å; F100-W225 AromaticContact CZ-CZ2 3.87Å; F100-W225 HydrophobicContact CZ-CZ2 3.87Å; F100-L246 HydrophobicContact CE2-CD2 4.26Å; F100-L246 HydrophobicContact CZ-CD2 4.39Å; F100-L250 HydrophobicContact CD2-CD1 4.19Å; F100-L250 HydrophobicContact CD2-CD2 3.81Å; F100-L250 HydrophobicContact CD2-CG 4.21Å; F100-L250 HydrophobicContact CE2-CD1 4.1Å; F100-L250 HydrophobicContact CE2-CD2 3.62Å; F100-L250 HydrophobicContact CE2-CG 3.76Å; F100-L250 HydrophobicContact CZ-CD2 4.42Å
101	G	92.9	Very high	89	Confident	0 Å²	0	21.9 Å²	21.9	0%	0	12%	0.123	C	C	.	.	H	α-helix	trans	-63.8	-48.1	179.2	0	0	0	0	0	112.5	L99 L103 F104 A105 L179	L99-G101 PolarHBondContact O-N 3.22Å; G101-L103 PolarHBondContact O-N 2.86Å; G101-F104 PolarHBondContact O-N 3.47Å; G101-A105 WeakPolarHBondContact O-CB 3.18Å; G101-A105 PolarHBondContact O-N 3.2Å; G101-L179 VanDerWaalsContact CA-CD2 3.44Å
102	V	95.6	Very high	90.4	Very high	18 Å²	18	17.9 Å²	17.9	11%	0.109	9%	0.094	C	C	.	.	H	α-helix	trans	-63.7	-44.9	-175.6	173.3	0	0	0	0	112	F98 L99 A105 V106 I145	F98-V102 HydrophobicContact CD2-CG2 4.27Å; F98-V102 HydrophobicContact CE1-CG2 4.38Å; F98-V102 HydrophobicContact CE2-CG2 3.95Å; F98-V102 HydrophobicContact CZ-CG2 4.01Å; F98-V102 VanDerWaalsContact O-CG2 3.31Å; F98-V102 WeakPolarHBondContact O-CG2 3.33Å; F98-V102 PolarHBondContact O-N 2.91Å; L99-V102 PolarHBondContact O-N 3.5Å; V102-A105 PolarHBondContact O-N 3.49Å; V102-V106 WeakPolarHBondContact O-CG2 3.45Å; V102-V106 PolarHBondContact O-N 2.87Å; V102-I145 HydrophobicContact CG1-CD1 4.41Å; V102-I145 HydrophobicContact CG1-CG1 3.88Å; V102-I145 HydrophobicContact CG2-CG1 3.98Å
103	L	95.8	Very high	91.5	Very high	23 Å²	23	16.6 Å²	16.6	12%	0.12	9%	0.086	C	C	.	.	H	α-helix	trans	-63.9	-44.6	-178.9	-70.1	169	0	0	0	112	G76 I77 L80 L99 G101 V106 C107	G76-L103 WeakPolarHBondContact O-CD1 3.37Å; I77-L103 HydrophobicContact CG1-CB 4.09Å; L80-L103 HydrophobicContact CB-CD1 4.16Å; L80-L103 HydrophobicContact CD2-CD1 4.14Å; L99-L103 HydrophobicContact CB-CD1 4.09Å; L99-L103 VanDerWaalsContact O-CB 3.23Å; L99-L103 WeakPolarHBondContact O-CB 3.39Å; L99-L103 WeakPolarHBondContact O-CD1 3.2Å; L99-L103 WeakPolarHBondContact O-CG 3.32Å; L99-L103 PolarHBondContact O-N 2.84Å; G101-L103 PolarHBondContact O-N 2.86Å; L103-V106 PolarHBondContact O-N 3.46Å; L103-C107 PolarHBondContact O-N 3.32Å; L103-C107 PolarHBondContact O-SG 3.07Å
104	F	95.7	Very high	92.4	Very high	2 Å²	2	14.6 Å²	14.6	1%	0.009	8%	0.079	C	C	.	.	H	α-helix	trans	-67.2	-37.5	175.2	-81.8	-64.7	0	0	0	112.4	I77 F100 G101 V106 C107 F108 V182 W222 L250 N253 F257	I77-F104 HydrophobicContact CD1-CD1 3.85Å; I77-F104 HydrophobicContact CD1-CE1 3.64Å; I77-F104 HydrophobicContact CD1-CG 4.45Å; I77-F104 HydrophobicContact CD1-CZ 4.12Å; I77-F104 HydrophobicContact CG1-CE1 4.43Å; I77-F104 HydrophobicContact CG1-CZ 4.46Å; F100-F104 AromaticContact CD1-CD2 3.83Å; F100-F104 HydrophobicContact CD1-CD2 3.83Å; F100-F104 HydrophobicContact CD1-CE2 4.08Å; F100-F104 HydrophobicContact CD2-CE2 4.36Å; F100-F104 AromaticContact CE1-CD2 3.68Å; F100-F104 HydrophobicContact CE1-CD2 3.68Å; F100-F104 AromaticContact CE1-CE2 3.63Å; F100-F104 HydrophobicContact CE1-CE2 3.63Å; F100-F104 AromaticContact CE2-CE2 3.97Å; F100-F104 HydrophobicContact CE2-CE2 3.97Å; F100-F104 HydrophobicContact CG-CD2 4.38Å; F100-F104 HydrophobicContact CG-CE2 4.43Å; F100-F104 HydrophobicContact CZ-CD2 4.14Å; F100-F104 AromaticContact CZ-CE2 3.59Å; F100-F104 HydrophobicContact CZ-CE2 3.59Å; F100-F104 VanDerWaalsContact O-CD2 3.28Å; F100-F104 WeakPolarHBondContact O-CD2 3.49Å; F100-F104 PolarHBondContact O-N 3.2Å; G101-F104 PolarHBondContact O-N 3.47Å; F104-V106 VanDerWaalsContact C-N 3.35Å; F104-V106 PolarHBondContact O-N 3.29Å; F104-C107 PolarHBondContact O-N 2.99Å; F104-F108 HydrophobicContact CB-CD2 4.27Å; F104-F108 HydrophobicContact CB-CE2 4.05Å; F104-F108 AromaticContact CD1-CE2 3.9Å; F104-F108 HydrophobicContact CD1-CE2 3.9Å; F104-F108 HydrophobicContact CD1-CZ 4.26Å; F104-F108 HydrophobicContact CG-CE2 4.34Å; F104-F108 WeakPolarHBondContact O-CD2 3.2Å; F104-F108 PolarHBondContact O-N 2.69Å; F104-V182 HydrophobicContact CB-CG1 3.65Å; F104-W222 HydrophobicContact CB-CZ2 4.03Å; F104-W222 HydrophobicContact CD1-CZ2 4Å; F104-W222 HydrophobicContact CD2-CH2 4.38Å; F104-W222 AromaticContact CD2-CZ2 3.68Å; F104-W222 HydrophobicContact CD2-CZ2 3.68Å; F104-W222 HydrophobicContact CE1-CZ2 4.4Å; F104-W222 HydrophobicContact CE2-CZ2 4.08Å; F104-W222 AromaticContact CG-CZ2 3.65Å; F104-W222 HydrophobicContact CG-CZ2 3.65Å; F104-W222 HydrophobicContact CZ-CZ2 4.42Å; F104-L250 HydrophobicContact CE2-CD2 3.55Å; F104-L250 HydrophobicContact CZ-CD2 3.84Å; F104-N253 HydrophobicContact CE1-CB 4.24Å; F104-N253 VanDerWaalsContact CE1-ND2 3.28Å; F104-N253 WeakPolarHBondContact CE1-ND2 3.45Å; F104-N253 HydrophobicContact CZ-CB 4.4Å; F104-F257 HydrophobicContact CD1-CE2 4.25Å; F104-F257 HydrophobicContact CD1-CZ 4.43Å; F104-F257 HydrophobicContact CE1-CE2 4.13Å; F104-F257 HydrophobicContact CE1-CZ 4.37Å
105	A	96.8	Very high	93.1	Very high	0 Å²	0	13.5 Å²	13.5	0%	0	7%	0.071	C	C	.	.	H	α-helix	trans	-61.3	-42.8	174.3	0	0	0	0	0	111.8	G101 V102 C107 S109 Q144 V182 L185	G101-A105 WeakPolarHBondContact O-CB 3.18Å; G101-A105 PolarHBondContact O-N 3.2Å; V102-A105 PolarHBondContact O-N 3.49Å; A105-C107 PolarHBondContact O-N 2.79Å; A105-S109 WeakPolarHBondContact O-CB 3.4Å; A105-S109 PolarHBondContact O-N 3.36Å; A105-S109 PolarHBondContact O-OG 3.26Å; A105-Q144 HydrophobicContact CB-CB 3.39Å; A105-Q144 HydrophobicContact CB-CG 3.61Å; A105-V182 HydrophobicContact CB-CG2 4.34Å; A105-L185 HydrophobicContact CB-CD1 4.25Å
106	V	97.1	Very high	93.7	Very high	26 Å²	26	16.7 Å²	16.7	16%	0.158	8%	0.077	C	C	.	.	H	α-helix	trans	-59.5	-47.1	173.7	171.7	0	0	0	0	110.7	V102 L103 F104 S109 C110	V102-V106 WeakPolarHBondContact O-CG2 3.45Å; V102-V106 PolarHBondContact O-N 2.87Å; L103-V106 PolarHBondContact O-N 3.46Å; F104-V106 VanDerWaalsContact C-N 3.35Å; F104-V106 PolarHBondContact O-N 3.29Å; V106-S109 PolarHBondContact O-N 3.47Å; V106-C110 PolarHBondContact O-N 3.43Å; V106-C110 PolarHBondContact O-SG 3.46Å
107	C	96.9	Very high	94	Very high	0 Å²	0	16.4 Å²	16.4	0%	0	8%	0.077	C	C	.	.	H	α-helix	trans	-61.4	-50.6	179.9	-64.2	0	0	0	0	112.4	F70 G73 L103 F104 A105 C110 L111 F257	F70-C107 HydrophobicContact CD2-CB 4.24Å; F70-C107 HydrophobicContact CE2-CB 4.04Å; G73-C107 VanDerWaalsContact C-SG 3.58Å; L103-C107 PolarHBondContact O-N 3.32Å; L103-C107 PolarHBondContact O-SG 3.07Å; F104-C107 PolarHBondContact O-N 2.99Å; A105-C107 PolarHBondContact O-N 2.79Å; C107-C110 WeakPolarHBondContact O-CB 3.5Å; C107-C110 PolarHBondContact O-N 3.42Å; C107-L111 PolarHBondContact O-N 2.93Å; C107-F257 HydrophobicContact CB-CD2 4.41Å; C107-F257 HydrophobicContact CB-CE2 3.77Å; C107-F257 HydrophobicContact CB-CZ 4.38Å
108	F	96.8	Very high	94.3	Very high	0 Å²	0	15.4 Å²	15.4	0%	0	7%	0.072	C	C	.	.	H	α-helix	trans	-70.4	-31.3	179	-65.5	-55	0	0	0	112.8	F104 C110 L111 L112 V182 L185 M186 I215 S218 W222 F257	F104-F108 HydrophobicContact CB-CD2 4.27Å; F104-F108 HydrophobicContact CB-CE2 4.05Å; F104-F108 AromaticContact CD1-CE2 3.9Å; F104-F108 HydrophobicContact CD1-CE2 3.9Å; F104-F108 HydrophobicContact CD1-CZ 4.26Å; F104-F108 HydrophobicContact CG-CE2 4.34Å; F104-F108 WeakPolarHBondContact O-CD2 3.2Å; F104-F108 PolarHBondContact O-N 2.69Å; F108-C110 VanDerWaalsContact C-N 3.29Å; F108-C110 PolarHBondContact O-N 3Å; F108-L111 HydrophobicContact CD1-CD1 3.99Å; F108-L111 HydrophobicContact CE1-CD1 4.39Å; F108-L111 PolarHBondContact O-N 3.27Å; F108-L112 WeakPolarHBondContact O-CB 3.36Å; F108-L112 PolarHBondContact O-N 3.01Å; F108-V182 HydrophobicContact CD2-CG1 3.59Å; F108-V182 HydrophobicContact CE2-CG1 3.71Å; F108-L185 HydrophobicContact CB-CB 4.07Å; F108-M186 HydrophobicContact CD1-CB 4.42Å; F108-M186 HydrophobicContact CD1-CG 4.21Å; F108-M186 HydrophobicContact CD2-CB 4.41Å; F108-M186 HydrophobicContact CD2-CE 4.47Å; F108-M186 HydrophobicContact CE1-CB 4.42Å; F108-M186 HydrophobicContact CE1-CE 4.46Å; F108-M186 HydrophobicContact CE1-CG 3.82Å; F108-M186 HydrophobicContact CE2-CB 4.39Å; F108-M186 HydrophobicContact CE2-CE 3.58Å; F108-M186 HydrophobicContact CE2-CG 4.35Å; F108-M186 HydrophobicContact CG-CB 4.45Å; F108-M186 HydrophobicContact CZ-CB 4.41Å; F108-M186 HydrophobicContact CZ-CE 3.59Å; F108-M186 HydrophobicContact CZ-CG 3.9Å; F108-M186 HydrophobicContact CZ-SD 4.12Å; F108-I215 HydrophobicContact CD1-CD1 3.63Å; F108-I215 HydrophobicContact CE1-CD1 3.5Å; F108-S218 VanDerWaalsContact CZ-OG 3.27Å; F108-S218 WeakPolarHBondContact CZ-OG 3.44Å; F108-W222 HydrophobicContact CE2-CZ2 4.16Å; F108-F257 HydrophobicContact CE1-CE1 4.25Å; F108-F257 AromaticContact CE1-CZ 3.85Å; F108-F257 HydrophobicContact CE1-CZ 3.85Å; F108-F257 AromaticContact CZ-CZ 3.98Å; F108-F257 HydrophobicContact CZ-CZ 3.98Å
109	S	97.3	Very high	94.3	Very high	0 Å²	0	13.5 Å²	13.5	0%	0	7%	0.065	C	C	.	.	H	α-helix	trans	-61.2	-40.7	172.1	-62.5	0	0	0	0	111.4	A105 V106 T113 F140 S141	A105-S109 WeakPolarHBondContact O-CB 3.4Å; A105-S109 PolarHBondContact O-N 3.36Å; A105-S109 PolarHBondContact O-OG 3.26Å; V106-S109 PolarHBondContact O-N 3.47Å; S109-T113 VanDerWaalsContact O-CB 3.28Å; S109-T113 WeakPolarHBondContact O-CB 3.15Å; S109-T113 PolarHBondContact O-N 3.06Å; S109-T113 PolarHBondContact O-OG1 3.48Å; S109-F140 WeakPolarHBondContact OG-CB 3.34Å; S109-S141 PolarHBondContact OG-N 3.28Å
110	C	96.1	Very high	94.1	Very high	0 Å²	0	13.1 Å²	13.1	0%	0	6%	0.06	C	C	.	.	H	α-helix	trans	-65.4	-47	175	-66.4	0	0	0	0	111.7	I66 F70 V106 C107 F108 L112 T113 H114	I66-C110 HydrophobicContact CG2-CB 3.91Å; F70-C110 HydrophobicContact CB-CB 3.98Å; F70-C110 HydrophobicContact CD2-CB 3.98Å; F70-C110 HydrophobicContact CG-CB 4.49Å; V106-C110 PolarHBondContact O-N 3.43Å; V106-C110 PolarHBondContact O-SG 3.46Å; C107-C110 WeakPolarHBondContact O-CB 3.5Å; C107-C110 PolarHBondContact O-N 3.42Å; F108-C110 VanDerWaalsContact C-N 3.29Å; F108-C110 PolarHBondContact O-N 3Å; C110-L112 PolarHBondContact O-N 3.28Å; C110-T113 PolarHBondContact O-N 3.03Å; C110-H114 WeakPolarHBondContact O-CB 3.49Å; C110-H114 PolarHBondContact O-N 3.46Å
111	L	95.4	Very high	93.8	Very high	0 Å²	0	13.4 Å²	13.4	0%	0	6%	0.062	C	C	.	.	H	α-helix	trans	-62	-43.2	177.3	-69.2	171.9	0	0	0	112.1	F70 C107 F108 H114 A115 T189 I211 F257 Y261	F70-L111 HydrophobicContact CD2-CD2 4.4Å; F70-L111 HydrophobicContact CD2-CG 4.17Å; F70-L111 HydrophobicContact CE2-CD1 3.88Å; F70-L111 HydrophobicContact CE2-CD2 3.85Å; F70-L111 HydrophobicContact CE2-CG 3.63Å; F70-L111 HydrophobicContact CZ-CD2 4.44Å; C107-L111 PolarHBondContact O-N 2.93Å; F108-L111 HydrophobicContact CD1-CD1 3.99Å; F108-L111 HydrophobicContact CE1-CD1 4.39Å; F108-L111 PolarHBondContact O-N 3.27Å; L111-H114 PolarHBondContact O-N 2.74Å; L111-A115 WeakPolarHBondContact O-CB 3.24Å; L111-A115 PolarHBondContact O-N 2.96Å; L111-T189 HydrophobicContact CB-CG2 3.84Å; L111-I211 HydrophobicContact CD2-CG2 4.41Å; L111-F257 HydrophobicContact CD1-CE1 4.36Å; L111-Y261 HydrophobicContact CD2-CD1 3.76Å; L111-Y261 HydrophobicContact CD2-CD2 3.8Å; L111-Y261 HydrophobicContact CD2-CE1 3.65Å; L111-Y261 HydrophobicContact CD2-CE2 3.7Å; L111-Y261 HydrophobicContact CD2-CG 3.82Å
112	L	96	Very high	93.4	Very high	6 Å²	6	13.5 Å²	13.5	3%	0.031	6%	0.062	C	C	.	.	H	α-helix	trans	-62.3	-47.6	177.4	179.7	57.5	0	0	0	111.5	F108 C110 H114 A115 Y116 F140 L185 L188 T189 V192	F108-L112 WeakPolarHBondContact O-CB 3.36Å; F108-L112 PolarHBondContact O-N 3.01Å; C110-L112 PolarHBondContact O-N 3.28Å; L112-H114 VanDerWaalsContact C-N 3.29Å; L112-H114 PolarHBondContact O-N 3.12Å; L112-A115 PolarHBondContact O-N 3.46Å; L112-Y116 WeakPolarHBondContact O-CB 3.41Å; L112-Y116 PolarHBondContact O-N 3.44Å; L112-F140 HydrophobicContact CD2-CD2 3.96Å; L112-F140 HydrophobicContact CD2-CE2 3.72Å; L112-F140 HydrophobicContact CD2-CG 4.48Å; L112-F140 HydrophobicContact CD2-CZ 4.05Å; L112-F140 HydrophobicContact CG-CE2 4.16Å; L112-L185 HydrophobicContact CD2-CD2 3.97Å; L112-L188 HydrophobicContact CD1-CD2 4.21Å; L112-L188 HydrophobicContact CD1-CG 3.87Å; L112-L188 HydrophobicContact CD2-CD2 3.65Å; L112-L188 HydrophobicContact CD2-CG 4.16Å; L112-T189 WeakPolarHBondContact CB-OG1 3.34Å; L112-V192 HydrophobicContact CD1-CB 4.08Å; L112-V192 HydrophobicContact CD1-CG1 4.37Å; L112-V192 HydrophobicContact CD1-CG2 3.87Å
113	T	95.6	Very high	92.8	Very high	0 Å²	0	19 Å²	19	0%	0	9%	0.085	C	C	.	.	H	α-helix	trans	-61.5	-41.3	178.3	-60	0	0	0	0	110.8	I66 S109 C110 Y116 N117 L133 L136 I137	I66-T113 HydrophobicContact CD1-CG2 4.29Å; S109-T113 VanDerWaalsContact O-CB 3.28Å; S109-T113 WeakPolarHBondContact O-CB 3.15Å; S109-T113 PolarHBondContact O-N 3.06Å; S109-T113 PolarHBondContact O-OG1 3.48Å; C110-T113 PolarHBondContact O-N 3.03Å; T113-Y116 PolarHBondContact O-N 3.24Å; T113-N117 PolarHBondContact O-N 3.44Å; T113-L133 HydrophobicContact CG2-CB 4.12Å; T113-L133 HydrophobicContact CG2-CD2 3.6Å; T113-L133 HydrophobicContact CG2-CG 4.49Å; T113-L136 HydrophobicContact CG2-CB 3.95Å; T113-L136 HydrophobicContact CG2-CD1 4.14Å; T113-I137 HydrophobicContact CG2-CG1 4.16Å
114	H	93.6	Very high	91.9	Very high	5 Å²	5	19.1 Å²	19.1	2%	0.023	9%	0.092	C	C	.	.	H	α-helix	trans	-65.3	-46.8	175.4	-168.3	-176.5	0	0	0	111.7	I66 C110 L111 L112 Y116 N117 L118 I211 Y261 E265	I66-H114 HydrophobicContact CD1-CB 4.46Å; I66-H114 HydrophobicContact CG2-CB 4.31Å; C110-H114 WeakPolarHBondContact O-CB 3.49Å; C110-H114 PolarHBondContact O-N 3.46Å; L111-H114 PolarHBondContact O-N 2.74Å; L112-H114 VanDerWaalsContact C-N 3.29Å; L112-H114 PolarHBondContact O-N 3.12Å; H114-Y116 VanDerWaalsContact C-N 3.27Å; H114-Y116 PolarHBondContact O-N 3.07Å; H114-N117 PolarHBondContact O-N 3.35Å; H114-N117 VanDerWaalsContact O-N 3.14Å; H114-L118 WeakPolarHBondContact O-CG 3.49Å; H114-L118 PolarHBondContact O-N 3.18Å; H114-I211 HydrophobicContact CB-CD1 4.05Å; H114-Y261 AromaticContact ND1-CE2 3.52Å; H114-Y261 AromaticContact ND1-CZ 3.67Å; H114-Y261 PolarHBondContact ND1-OH 3.47Å; H114-E265 IonicContact CE1-OE2 3.42Å; H114-E265 PolarHBondContact CE1-OE2 3.45Å
115	A	93.7	Very high	91.3	Very high	0 Å²	0	27 Å²	27	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-59.3	-38.6	176.6	0	0	0	0	0	112.1	L111 L112 L118 N119 V192 I211	L111-A115 WeakPolarHBondContact O-CB 3.24Å; L111-A115 PolarHBondContact O-N 2.96Å; L112-A115 PolarHBondContact O-N 3.46Å; A115-L118 PolarHBondContact O-N 3.24Å; A115-N119 PolarHBondContact O-N 3.05Å; A115-V192 HydrophobicContact CB-CB 4.43Å; A115-V192 HydrophobicContact CB-CG1 3.74Å; A115-I211 HydrophobicContact CB-CG2 4.49Å
116	Y	92.9	Very high	90.6	Very high	125 Å²	125	33.5 Å²	33.5	49%	0.49	15%	0.15	S	C	.	.	H	α-helix	trans	-66.1	-42.1	175.7	-169.8	-111.6	0	0	0	112.3	L112 T113 H114 N119 K120 F128 L136	L112-Y116 WeakPolarHBondContact O-CB 3.41Å; L112-Y116 PolarHBondContact O-N 3.44Å; T113-Y116 PolarHBondContact O-N 3.24Å; H114-Y116 VanDerWaalsContact C-N 3.27Å; H114-Y116 PolarHBondContact O-N 3.07Å; Y116-N119 PolarHBondContact O-N 3.49Å; Y116-K120 PolarHBondContact O-N 2.81Å; Y116-F128 HydrophobicContact CD1-CD2 4.18Å; Y116-F128 AromaticContact CD1-CE2 3.33Å; Y116-F128 HydrophobicContact CD1-CE2 3.33Å; Y116-F128 AromaticContact CD1-CZ 3.78Å; Y116-F128 HydrophobicContact CD1-CZ 3.78Å; Y116-F128 HydrophobicContact CE1-CD2 4.41Å; Y116-F128 HydrophobicContact CE1-CE1 4.26Å; Y116-F128 AromaticContact CE1-CE2 3.3Å; Y116-F128 HydrophobicContact CE1-CE2 3.3Å; Y116-F128 AromaticContact CE1-CZ 3.2Å; Y116-F128 HydrophobicContact CE1-CZ 3.2Å; Y116-F128 HydrophobicContact CG-CE2 4.43Å; Y116-L136 HydrophobicContact CD1-CD1 4.37Å
117	N	91.4	Very high	90	Very high	2 Å²	2	34.3 Å²	34.3	1%	0.011	16%	0.156	C	C	.	.	H	α-helix	trans	-63.6	-43.5	174	-172.5	59.6	0	0	0	111.7	M63 T113 H114 N119 K120 L121 F128 L133	M63-N117 WeakPolarHBondContact CE-ND2 3.31Å; M63-N117 PolarHBondContact SD-ND2 3.43Å; T113-N117 PolarHBondContact O-N 3.44Å; H114-N117 PolarHBondContact O-N 3.35Å; H114-N117 VanDerWaalsContact O-N 3.14Å; N117-N119 PolarHBondContact O-N 2.97Å; N117-K120 WeakPolarHBondContact O-CB 3.39Å; N117-K120 PolarHBondContact O-N 3.27Å; N117-K120 VanDerWaalsContact O-N 3.14Å; N117-L121 WeakPolarHBondContact O-CG 3.46Å; N117-L121 PolarHBondContact O-N 3.41Å; N117-L121 VanDerWaalsContact O-N 3.09Å; N117-F128 HydrophobicContact CB-CD2 4.29Å; N117-F128 PolarHBondContact OD1-N 3.42Å; N117-L133 HydrophobicContact CB-CD2 4.03Å
118	L	88.8	Confident	89.3	Confident	1 Å²	1	36.1 Å²	36.1	1%	0.005	16%	0.163	C	C	.	.	H	α-helix	trans	-61.6	-41.6	176.3	-73.5	174.9	0	0	0	112.1	H114 A115 K120 L121 V122 T196 W204 H207 I211	H114-L118 WeakPolarHBondContact O-CG 3.49Å; H114-L118 PolarHBondContact O-N 3.18Å; A115-L118 PolarHBondContact O-N 3.24Å; L118-K120 PolarHBondContact O-N 3.02Å; L118-L121 HydrophobicContact CD2-CD1 4.34Å; L118-L121 PolarHBondContact O-N 3.27Å; L118-L121 VanDerWaalsContact O-N 3.07Å; L118-V122 WeakPolarHBondContact O-CB 3.5Å; L118-V122 WeakPolarHBondContact O-CG2 3.28Å; L118-V122 PolarHBondContact O-N 3.06Å; L118-T196 HydrophobicContact CB-CG2 4.22Å; L118-W204 HydrophobicContact CD2-CE3 3.71Å; L118-W204 HydrophobicContact CD2-CZ3 4.32Å; L118-H207 HydrophobicContact CD1-CB 4.05Å; L118-H207 HydrophobicContact CD2-CB 3.98Å; L118-I211 HydrophobicContact CD1-CD1 3.5Å; L118-I211 VanDerWaalsContact CD1-CD1 3.5Å; L118-I211 HydrophobicContact CD1-CG1 4.46Å
119	N	89.4	Confident	88.9	Confident	16 Å²	16	39.1 Å²	39.1	9%	0.086	19%	0.185	C	C	.	.	H	α-helix	trans	-58.2	-32.6	175.8	-84	-23.5	0	0	0	113.5	A115 Y116 N117 K123 V192 F195 T196	A115-N119 PolarHBondContact O-N 3.05Å; Y116-N119 PolarHBondContact O-N 3.49Å; N117-N119 PolarHBondContact O-N 2.97Å; N119-K123 WeakPolarHBondContact O-CD 3.3Å; N119-K123 VanDerWaalsContact O-CG 3.28Å; N119-K123 WeakPolarHBondContact O-CG 3.42Å; N119-K123 PolarHBondContact O-N 3.44Å; N119-V192 WeakPolarHBondContact ND2-CG1 3.34Å; N119-V192 PolarHBondContact ND2-O 2.76Å; N119-F195 PolarHBondContact OD1-O 2.92Å; N119-T196 WeakPolarHBondContact OD1-CA 3.25Å; N119-T196 WeakPolarHBondContact OD1-CG2 3.14Å; N119-T196 PolarHBondContact OD1-N 2.98Å
120	K	85.9	Confident	88.3	Confident	51 Å²	51	44.3 Å²	44.3	22%	0.222	20%	0.204	C	C	.	.	H	α-helix	trans	-72.5	-44.4	175.4	-167	172.5	-178.3	-152.8	0	110.8	Y116 N117 L118 K123 G124 R125 K126 F128	Y116-K120 PolarHBondContact O-N 2.81Å; N117-K120 WeakPolarHBondContact O-CB 3.39Å; N117-K120 PolarHBondContact O-N 3.27Å; N117-K120 VanDerWaalsContact O-N 3.14Å; L118-K120 PolarHBondContact O-N 3.02Å; K120-K123 PolarHBondContact O-N 3.42Å; K120-G124 PolarHBondContact O-N 3.49Å; K120-R125 HydrophobicContact CD-CB 4.28Å; K120-R125 HydrophobicContact CG-CB 3.35Å; K120-R125 HydrophobicContact CG-CG 4.37Å; K120-R125 WeakPolarHBondContact O-CB 3.13Å; K120-R125 PolarHBondContact O-N 2.8Å; K120-K126 WeakPolarHBondContact CD-O 3.23Å; K120-K126 WeakPolarHBondContact CE-O 3.21Å; K120-K126 PolarHBondContact NZ-O 2.91Å; K120-F128 HydrophobicContact CB-CE2 4.41Å; K120-F128 HydrophobicContact CD-CD2 4.14Å; K120-F128 HydrophobicContact CD-CE1 4.17Å; K120-F128 HydrophobicContact CD-CE2 3.62Å; K120-F128 HydrophobicContact CD-CZ 3.63Å
121	L	85.5	Confident	88.1	Confident	7 Å²	7	49.8 Å²	49.8	4%	0.037	23%	0.233	C	C	.	.	H	α-helix	trans	-63.6	-44.5	178.1	-68.9	171.4	0	0	0	112.7	N117 L118 K123 G124 P127 W204	N117-L121 WeakPolarHBondContact O-CG 3.46Å; N117-L121 PolarHBondContact O-N 3.41Å; N117-L121 VanDerWaalsContact O-N 3.09Å; L118-L121 HydrophobicContact CD2-CD1 4.34Å; L118-L121 PolarHBondContact O-N 3.27Å; L118-L121 VanDerWaalsContact O-N 3.07Å; L121-K123 PolarHBondContact O-N 3.41Å; L121-G124 PolarHBondContact O-N 2.99Å; L121-P127 HydrophobicContact CD2-CB 4.02Å; L121-P127 HydrophobicContact CD2-CG 4.37Å; L121-W204 HydrophobicContact CB-CD2 4.12Å; L121-W204 HydrophobicContact CB-CG 4.23Å; L121-W204 HydrophobicContact CD1-CD2 4.23Å; L121-W204 HydrophobicContact CD1-CE3 3.93Å; L121-W204 HydrophobicContact CD1-CH2 4.04Å; L121-W204 HydrophobicContact CD1-CZ2 4.33Å; L121-W204 HydrophobicContact CD1-CZ3 3.83Å
122	V	84.6	Confident	88	Confident	1 Å²	1	52.6 Å²	52.6	1%	0.006	25%	0.25	C	C	.	.	H	α-helix	trans	-64.4	-24	178.6	177.9	0	0	0	0	111.8	L118 T196 S200 W204 K205	L118-V122 WeakPolarHBondContact O-CB 3.5Å; L118-V122 WeakPolarHBondContact O-CG2 3.28Å; L118-V122 PolarHBondContact O-N 3.06Å; V122-T196 WeakPolarHBondContact CG1-O 3.4Å; V122-S200 PolarHBondContact O-N 3.04Å; V122-S200 VanDerWaalsContact O-N 3.14Å; V122-W204 HydrophobicContact CG2-CB 3.47Å; V122-W204 VanDerWaalsContact CG2-CB 3.47Å; V122-K205 HydrophobicContact CG1-CG 4.3Å
123	K	83.4	Confident	87.8	Confident	133 Å²	133	52.3 Å²	52.3	58%	0.578	25%	0.249	S	C	*	.	T	Hydrogen-bonded Turn	trans	-88.9	5.3	172.6	-67.3	176.3	-175.4	-179.6	0	113.7	N119 K120 L121 R125	N119-K123 WeakPolarHBondContact O-CD 3.3Å; N119-K123 VanDerWaalsContact O-CG 3.28Å; N119-K123 WeakPolarHBondContact O-CG 3.42Å; N119-K123 PolarHBondContact O-N 3.44Å; K120-K123 PolarHBondContact O-N 3.42Å; L121-K123 PolarHBondContact O-N 3.41Å; K123-R125 VanDerWaalsContact C-N 3.3Å; K123-R125 PolarHBondContact O-N 2.98Å
124	G	77.9	Confident	87.7	Confident	27 Å²	27	54.1 Å²	54.1	28%	0.278	26%	0.258	S	S	.	.	T	Hydrogen-bonded Turn	trans	73.2	16.4	179.8	0	0	0	0	0	114.7	K120 L121	K120-G124 PolarHBondContact O-N 3.49Å; L121-G124 PolarHBondContact O-N 2.99Å
125	R	81.9	Confident	87.8	Confident	166 Å²	166	59.4 Å²	59.4	63%	0.626	29%	0.286	S	S	*	.	P	Polyproline II helix	trans	-90.8	152.2	176.6	-68.2	-179.4	-178.3	-171.4	-0.3	110.1	K120 K123	K120-R125 HydrophobicContact CD-CB 4.28Å; K120-R125 HydrophobicContact CG-CB 3.35Å; K120-R125 HydrophobicContact CG-CG 4.37Å; K120-R125 WeakPolarHBondContact O-CB 3.13Å; K120-R125 PolarHBondContact O-N 2.8Å; K123-R125 VanDerWaalsContact C-N 3.3Å; K123-R125 PolarHBondContact O-N 2.98Å
126	K	81.7	Confident	87.9	Confident	138 Å²	138	61.4 Å²	61.4	60%	0.6	30%	0.296	S	S	*	.	P	Polyproline II helix	trans	-57.9	142.6	178.3	-62.1	-169.5	178.4	-165.2	0	111.7	K120	K120-K126 WeakPolarHBondContact CD-O 3.23Å; K120-K126 WeakPolarHBondContact CE-O 3.21Å; K120-K126 PolarHBondContact NZ-O 2.91Å
127	P	84.2	Confident	88	Confident	42 Å²	42	55.7 Å²	55.7	27%	0.273	27%	0.274	S	S	.	.	P	Polyproline II helix	trans	-59.6	164.6	176.5	24.1	-32.5	0	0	0	112	L121	L121-P127 HydrophobicContact CD2-CB 4.02Å; L121-P127 HydrophobicContact CD2-CG 4.37Å
128	F	84.1	Confident	88.2	Confident	38 Å²	38	59.6 Å²	59.6	17%	0.167	29%	0.294	C	S	.	.	P	Polyproline II helix	trans	-71.9	151	170.3	-72.5	-71.7	0	0	0	111.7	Y116 N117 K120 V132 L133	Y116-F128 HydrophobicContact CD1-CD2 4.18Å; Y116-F128 AromaticContact CD1-CE2 3.33Å; Y116-F128 HydrophobicContact CD1-CE2 3.33Å; Y116-F128 AromaticContact CD1-CZ 3.78Å; Y116-F128 HydrophobicContact CD1-CZ 3.78Å; Y116-F128 HydrophobicContact CE1-CD2 4.41Å; Y116-F128 HydrophobicContact CE1-CE1 4.26Å; Y116-F128 AromaticContact CE1-CE2 3.3Å; Y116-F128 HydrophobicContact CE1-CE2 3.3Å; Y116-F128 AromaticContact CE1-CZ 3.2Å; Y116-F128 HydrophobicContact CE1-CZ 3.2Å; Y116-F128 HydrophobicContact CG-CE2 4.43Å; N117-F128 HydrophobicContact CB-CD2 4.29Å; N117-F128 PolarHBondContact OD1-N 3.42Å; K120-F128 HydrophobicContact CB-CE2 4.41Å; K120-F128 HydrophobicContact CD-CD2 4.14Å; K120-F128 HydrophobicContact CD-CE1 4.17Å; K120-F128 HydrophobicContact CD-CE2 3.62Å; K120-F128 HydrophobicContact CD-CZ 3.63Å; F128-V132 HydrophobicContact CB-CB 4.38Å; F128-V132 HydrophobicContact CB-CG1 4.41Å; F128-V132 HydrophobicContact CD1-CB 4.48Å; F128-V132 HydrophobicContact CD1-CG1 3.86Å; F128-V132 HydrophobicContact CG-CG1 4.32Å; F128-L133 HydrophobicContact CB-CD1 4.44Å; F128-L133 HydrophobicContact CB-CD2 3.83Å; F128-L133 HydrophobicContact CB-CG 3.88Å; F128-L133 HydrophobicContact CD2-CD2 4.4Å; F128-L133 HydrophobicContact CG-CD2 4.49Å
129	S	87.4	Confident	88.6	Confident	64 Å²	64	61.7 Å²	61.7	45%	0.448	31%	0.312	S	S	.	.	P	Polyproline II helix	trans	-63.4	147.2	167.8	176.9	0	0	0	0	109.6	L131 V132 L133	S129-L131 PolarHBondContact O-N 3.3Å; S129-V132 WeakPolarHBondContact O-CB 3.16Å; S129-V132 PolarHBondContact O-N 2.94Å; S129-L133 PolarHBondContact O-N 3.45Å; S129-L133 VanDerWaalsContact O-N 3.16Å
130	W	85.9	Confident	89	Confident	109 Å²	109	63.7 Å²	63.7	41%	0.413	32%	0.32	S	S	.	.	H	α-helix	trans	-52.4	-40.1	177.6	179.6	57.1	0	0	0	113.3	H62 A65 V132 L133 L134	H62-W130 HydrophobicContact CB-CB 4.08Å; H62-W130 VanDerWaalsContact O-CD1 3.25Å; A65-W130 HydrophobicContact CB-CZ2 4.13Å; W130-V132 VanDerWaalsContact C-N 3.31Å; W130-V132 PolarHBondContact O-N 3.31Å; W130-L133 PolarHBondContact O-N 2.9Å; W130-L134 PolarHBondContact O-N 2.95Å
131	L	91.3	Very high	89.4	Confident	114 Å²	114	61.9 Å²	61.9	60%	0.597	31%	0.314	S	S	*	.	H	α-helix	trans	-62.8	-37.4	177.7	-64.7	177.8	0	0	0	112.5	S129 L135	S129-L131 PolarHBondContact O-N 3.3Å; L131-L135 VanDerWaalsContact O-CB 3.32Å; L131-L135 WeakPolarHBondContact O-CB 3.27Å; L131-L135 PolarHBondContact O-N 3.41Å
132	V	92.6	Very high	90	Very high	59 Å²	59	66 Å²	66	36%	0.358	34%	0.335	S	S	.	.	H	α-helix	trans	-70.3	-40	178.9	177.7	0	0	0	0	110.4	F128 S129 W130 L135 L136	F128-V132 HydrophobicContact CB-CB 4.38Å; F128-V132 HydrophobicContact CB-CG1 4.41Å; F128-V132 HydrophobicContact CD1-CB 4.48Å; F128-V132 HydrophobicContact CD1-CG1 3.86Å; F128-V132 HydrophobicContact CG-CG1 4.32Å; S129-V132 WeakPolarHBondContact O-CB 3.16Å; S129-V132 PolarHBondContact O-N 2.94Å; W130-V132 VanDerWaalsContact C-N 3.31Å; W130-V132 PolarHBondContact O-N 3.31Å; V132-L135 PolarHBondContact O-N 3.15Å; V132-L136 HydrophobicContact CG1-CD1 4.39Å; V132-L136 WeakPolarHBondContact O-CG 3.44Å; V132-L136 PolarHBondContact O-N 3.2Å
133	L	92.4	Very high	90.5	Very high	1 Å²	1	68.9 Å²	68.9	1%	0.005	35%	0.353	C	S	.	.	H	α-helix	trans	-63.6	-44.5	176.1	-62.8	165.1	0	0	0	111	M63 I66 T113 N117 F128 S129 W130 L136 I137	M63-L133 HydrophobicContact CE-CD1 3.31Å; I66-L133 HydrophobicContact CD1-CB 4.36Å; I66-L133 HydrophobicContact CD1-CD1 4.23Å; I66-L133 HydrophobicContact CD1-CD2 4.16Å; I66-L133 HydrophobicContact CD1-CG 4.48Å; T113-L133 HydrophobicContact CG2-CB 4.12Å; T113-L133 HydrophobicContact CG2-CD2 3.6Å; T113-L133 HydrophobicContact CG2-CG 4.49Å; N117-L133 HydrophobicContact CB-CD2 4.03Å; F128-L133 HydrophobicContact CB-CD1 4.44Å; F128-L133 HydrophobicContact CB-CD2 3.83Å; F128-L133 HydrophobicContact CB-CG 3.88Å; F128-L133 HydrophobicContact CD2-CD2 4.4Å; F128-L133 HydrophobicContact CG-CD2 4.49Å; S129-L133 PolarHBondContact O-N 3.45Å; S129-L133 VanDerWaalsContact O-N 3.16Å; W130-L133 PolarHBondContact O-N 2.9Å; L133-L136 PolarHBondContact O-N 3.21Å; L133-I137 WeakPolarHBondContact O-CG1 3.39Å; L133-I137 PolarHBondContact O-N 3.04Å; L133-I137 VanDerWaalsContact O-N 3.09Å
134	L	93.6	Very high	91.2	Very high	38 Å²	38	62.5 Å²	62.5	20%	0.199	33%	0.325	C	S	.	.	H	α-helix	trans	-60.4	-46.3	175.5	-176.2	69.5	0	0	0	111.4	F69 W130 L136 I137 I138	F69-L134 HydrophobicContact CD2-CD1 4.2Å; F69-L134 HydrophobicContact CE2-CD1 3.32Å; F69-L134 HydrophobicContact CZ-CD1 3.81Å; W130-L134 PolarHBondContact O-N 2.95Å; L134-L136 VanDerWaalsContact C-N 3.32Å; L134-L136 PolarHBondContact O-N 3.29Å; L134-I137 PolarHBondContact O-N 2.83Å; L134-I138 HydrophobicContact CD1-CD1 4.17Å; L134-I138 HydrophobicContact CD2-CD1 4.45Å; L134-I138 HydrophobicContact CG-CD1 3.87Å; L134-I138 WeakPolarHBondContact O-CG1 3.38Å; L134-I138 PolarHBondContact O-N 3.43Å
135	L	95.5	Very high	92	Very high	116 Å²	116	63.5 Å²	63.5	61%	0.607	32%	0.323	S	S	*	.	H	α-helix	trans	-59.1	-42.2	177.7	-178.1	66.9	0	0	0	111.7	L131 V132 I138 A139	L131-L135 VanDerWaalsContact O-CB 3.32Å; L131-L135 WeakPolarHBondContact O-CB 3.27Å; L131-L135 PolarHBondContact O-N 3.41Å; V132-L135 PolarHBondContact O-N 3.15Å; L135-I138 PolarHBondContact O-N 3.05Å; L135-A139 WeakPolarHBondContact O-CB 3.37Å; L135-A139 PolarHBondContact O-N 3.49Å
136	L	95.6	Very high	92.7	Very high	42 Å²	42	59.2 Å²	59.2	22%	0.22	32%	0.316	C	S	.	.	H	α-helix	trans	-63.6	-44.6	177.3	-74.5	172.1	0	0	0	112.2	T113 Y116 V132 L133 L134 I138 A139 F140	T113-L136 HydrophobicContact CG2-CB 3.95Å; T113-L136 HydrophobicContact CG2-CD1 4.14Å; Y116-L136 HydrophobicContact CD1-CD1 4.37Å; V132-L136 HydrophobicContact CG1-CD1 4.39Å; V132-L136 WeakPolarHBondContact O-CG 3.44Å; V132-L136 PolarHBondContact O-N 3.2Å; L133-L136 PolarHBondContact O-N 3.21Å; L134-L136 VanDerWaalsContact C-N 3.32Å; L134-L136 PolarHBondContact O-N 3.29Å; L136-I138 PolarHBondContact O-N 2.84Å; L136-A139 PolarHBondContact O-N 3.41Å; L136-F140 HydrophobicContact CB-CE2 4.18Å; L136-F140 HydrophobicContact CD2-CE2 4.11Å; L136-F140 HydrophobicContact CD2-CZ 4.07Å; L136-F140 WeakPolarHBondContact O-CD2 3.42Å; L136-F140 WeakPolarHBondContact O-CG 3.12Å; L136-F140 PolarHBondContact O-N 3.39Å
137	I	95.8	Very high	93.3	Very high	4 Å²	4	55.3 Å²	55.3	2%	0.021	30%	0.3	C	S	.	.	H	α-helix	trans	-60.4	-47.8	177.2	-67.4	166.6	0	0	0	110.5	I66 T113 L133 L134 S141	I66-I137 HydrophobicContact CB-CD1 4.35Å; I66-I137 HydrophobicContact CG1-CD1 4.01Å; I66-I137 HydrophobicContact CG2-CD1 4.36Å; T113-I137 HydrophobicContact CG2-CG1 4.16Å; L133-I137 WeakPolarHBondContact O-CG1 3.39Å; L133-I137 PolarHBondContact O-N 3.04Å; L133-I137 VanDerWaalsContact O-N 3.09Å; L134-I137 PolarHBondContact O-N 2.83Å; I137-S141 WeakPolarHBondContact O-CB 3.32Å; I137-S141 PolarHBondContact O-N 2.86Å; I137-S141 PolarHBondContact O-OG 3.32Å
138	I	95.9	Very high	93.8	Very high	84 Å²	84	53.5 Å²	53.5	43%	0.431	29%	0.289	S	S	.	.	H	α-helix	trans	-64	-46.9	179.1	-65.9	171	0	0	0	110.1	L134 L135 L136 F140 S141 L142	L134-I138 HydrophobicContact CD1-CD1 4.17Å; L134-I138 HydrophobicContact CD2-CD1 4.45Å; L134-I138 HydrophobicContact CG-CD1 3.87Å; L134-I138 WeakPolarHBondContact O-CG1 3.38Å; L134-I138 PolarHBondContact O-N 3.43Å; L135-I138 PolarHBondContact O-N 3.05Å; L136-I138 PolarHBondContact O-N 2.84Å; I138-F140 PolarHBondContact O-N 2.92Å; I138-S141 PolarHBondContact O-N 3.14Å; I138-S141 PolarHBondContact O-OG 3.32Å; I138-S141 VanDerWaalsContact O-OG 3.07Å; I138-L142 WeakPolarHBondContact O-CB 3.44Å; I138-L142 PolarHBondContact O-N 3.36Å
139	A	96.5	Very high	94.2	Very high	46 Å²	46	55.7 Å²	55.7	38%	0.38	30%	0.301	S	S	.	.	H	α-helix	trans	-60	-46.1	-178.3	0	0	0	0	0	112.4	L135 L136	L135-A139 WeakPolarHBondContact O-CB 3.37Å; L135-A139 PolarHBondContact O-N 3.49Å; L136-A139 PolarHBondContact O-N 3.41Å
140	F	96.6	Very high	94.5	Very high	58 Å²	58	58.6 Å²	58.6	25%	0.254	31%	0.308	S	S	.	.	H	α-helix	trans	-69.9	-41.7	178.5	-63.7	-40	0	0	0	112.3	S109 L112 L136 I138 L142 Y181 L185	S109-F140 WeakPolarHBondContact OG-CB 3.34Å; L112-F140 HydrophobicContact CD2-CD2 3.96Å; L112-F140 HydrophobicContact CD2-CE2 3.72Å; L112-F140 HydrophobicContact CD2-CG 4.48Å; L112-F140 HydrophobicContact CD2-CZ 4.05Å; L112-F140 HydrophobicContact CG-CE2 4.16Å; L136-F140 HydrophobicContact CB-CE2 4.18Å; L136-F140 HydrophobicContact CD2-CE2 4.11Å; L136-F140 HydrophobicContact CD2-CZ 4.07Å; L136-F140 WeakPolarHBondContact O-CD2 3.42Å; L136-F140 WeakPolarHBondContact O-CG 3.12Å; L136-F140 PolarHBondContact O-N 3.39Å; I138-F140 PolarHBondContact O-N 2.92Å; F140-L142 PolarHBondContact O-N 2.83Å; F140-Y181 VanDerWaalsContact O-CE1 3.29Å; F140-Y181 WeakPolarHBondContact O-CE1 3.29Å; F140-Y181 PolarHBondContact O-OH 2.85Å; F140-L185 HydrophobicContact CB-CD2 4.22Å; F140-L185 HydrophobicContact CG-CD2 4.38Å
141	S	95.6	Very high	94.7	Very high	13 Å²	13	55 Å²	55	9%	0.091	30%	0.295	C	S	.	.	H	α-helix	trans	-67.9	-34.5	178.5	62.2	0	0	0	0	113.1	S109 I137 I138 V143 Q144 I145	S109-S141 PolarHBondContact OG-N 3.28Å; I137-S141 WeakPolarHBondContact O-CB 3.32Å; I137-S141 PolarHBondContact O-N 2.86Å; I137-S141 PolarHBondContact O-OG 3.32Å; I138-S141 PolarHBondContact O-N 3.14Å; I138-S141 PolarHBondContact O-OG 3.32Å; I138-S141 VanDerWaalsContact O-OG 3.07Å; S141-V143 VanDerWaalsContact C-N 3.28Å; S141-V143 PolarHBondContact O-N 3.03Å; S141-Q144 PolarHBondContact O-N 3.14Å; S141-I145 WeakPolarHBondContact O-CG1 3.29Å; S141-I145 PolarHBondContact O-N 2.84Å; S141-I145 VanDerWaalsContact O-N 3.12Å
142	L	96.7	Very high	94.6	Very high	92 Å²	92	50.8 Å²	50.8	48%	0.482	27%	0.272	S	S	.	.	H	α-helix	trans	-59.6	-37.6	-178.8	-175.8	66.1	0	0	0	112.3	I138 F140 Q144 I145 V146	I138-L142 WeakPolarHBondContact O-CB 3.44Å; I138-L142 PolarHBondContact O-N 3.36Å; F140-L142 PolarHBondContact O-N 2.83Å; L142-Q144 VanDerWaalsContact C-N 3.34Å; L142-Q144 PolarHBondContact O-N 3.36Å; L142-I145 WeakPolarHBondContact O-CB 3.45Å; L142-I145 PolarHBondContact O-N 3.49Å; L142-I145 VanDerWaalsContact O-N 3.16Å; L142-V146 HydrophobicContact CD1-CG2 4.49Å; L142-V146 HydrophobicContact CG-CG2 4.41Å; L142-V146 WeakPolarHBondContact O-CG2 3.25Å; L142-V146 PolarHBondContact O-N 3.43Å
143	V	97.1	Very high	94.5	Very high	62 Å²	62	51.8 Å²	51.8	38%	0.376	28%	0.278	S	S	.	.	H	α-helix	trans	-60.2	-45.4	178.7	177.8	0	0	0	0	110.8	S141 I145 V146 I147 Y181	S141-V143 VanDerWaalsContact C-N 3.28Å; S141-V143 PolarHBondContact O-N 3.03Å; V143-I145 VanDerWaalsContact C-N 3.33Å; V143-I145 PolarHBondContact O-N 3.13Å; V143-V146 PolarHBondContact O-N 3.43Å; V143-I147 HydrophobicContact CG1-CD1 3.96Å; V143-I147 VanDerWaalsContact O-CG1 3.31Å; V143-I147 WeakPolarHBondContact O-CG1 3.3Å; V143-I147 PolarHBondContact O-N 3.32Å; V143-Y181 HydrophobicContact CB-CD1 4.46Å; V143-Y181 HydrophobicContact CB-CE1 3.8Å; V143-Y181 HydrophobicContact CB-CE2 3.98Å; V143-Y181 HydrophobicContact CG1-CD1 4.24Å; V143-Y181 HydrophobicContact CG1-CD2 3.8Å; V143-Y181 HydrophobicContact CG1-CE1 3.99Å; V143-Y181 HydrophobicContact CG1-CE2 3.55Å; V143-Y181 HydrophobicContact CG1-CG 4.14Å
144	Q	96.5	Very high	94.3	Very high	0 Å²	0	54.6 Å²	54.6	0%	0	30%	0.296	C	S	.	.	H	α-helix	trans	-65.7	-38	176.2	-174	63.8	34.6	0	0	111.9	A105 S141 L142 V146 I147 S148 L178 Y181 V182	A105-Q144 HydrophobicContact CB-CB 3.39Å; A105-Q144 HydrophobicContact CB-CG 3.61Å; S141-Q144 PolarHBondContact O-N 3.14Å; L142-Q144 VanDerWaalsContact C-N 3.34Å; L142-Q144 PolarHBondContact O-N 3.36Å; Q144-V146 VanDerWaalsContact C-N 3.35Å; Q144-I147 PolarHBondContact O-N 2.89Å; Q144-S148 PolarHBondContact NE2-OG 3.22Å; Q144-S148 VanDerWaalsContact O-CB 3.32Å; Q144-S148 WeakPolarHBondContact O-CB 3.36Å; Q144-S148 PolarHBondContact O-N 3.45Å; Q144-S148 PolarHBondContact O-OG 3.49Å; Q144-L178 PolarHBondContact NE2-O 2.99Å; Q144-Y181 HydrophobicContact CB-CD1 3.85Å; Q144-Y181 HydrophobicContact CB-CE1 4.14Å; Q144-V182 HydrophobicContact CG-CG2 4.22Å
145	I	95.8	Very high	94	Very high	47 Å²	47	53.8 Å²	53.8	24%	0.241	29%	0.291	C	S	.	.	H	α-helix	trans	-61.1	-47.1	178.2	-67.4	167	0	0	0	109.8	V102 S141 L142 V143 S148 I149	V102-I145 HydrophobicContact CG1-CD1 4.41Å; V102-I145 HydrophobicContact CG1-CG1 3.88Å; V102-I145 HydrophobicContact CG2-CG1 3.98Å; S141-I145 WeakPolarHBondContact O-CG1 3.29Å; S141-I145 PolarHBondContact O-N 2.84Å; S141-I145 VanDerWaalsContact O-N 3.12Å; L142-I145 WeakPolarHBondContact O-CB 3.45Å; L142-I145 PolarHBondContact O-N 3.49Å; L142-I145 VanDerWaalsContact O-N 3.16Å; V143-I145 VanDerWaalsContact C-N 3.33Å; V143-I145 PolarHBondContact O-N 3.13Å; I145-S148 PolarHBondContact O-N 3.3Å; I145-I149 HydrophobicContact CG2-CD1 3.63Å; I145-I149 HydrophobicContact CG2-CG1 4.3Å; I145-I149 WeakPolarHBondContact O-CB 3.41Å; I145-I149 VanDerWaalsContact O-CG1 3.26Å; I145-I149 WeakPolarHBondContact O-CG1 3.17Å; I145-I149 PolarHBondContact O-N 3.38Å
146	V	96.1	Very high	93.5	Very high	77 Å²	77	52.2 Å²	52.2	47%	0.467	28%	0.283	S	S	.	.	H	α-helix	trans	-60	-50	177.8	172.9	0	0	0	0	111	L142 V143 Q144 S148 I149 E150	L142-V146 HydrophobicContact CD1-CG2 4.49Å; L142-V146 HydrophobicContact CG-CG2 4.41Å; L142-V146 WeakPolarHBondContact O-CG2 3.25Å; L142-V146 PolarHBondContact O-N 3.43Å; V143-V146 PolarHBondContact O-N 3.43Å; Q144-V146 VanDerWaalsContact C-N 3.35Å; V146-S148 VanDerWaalsContact C-N 3.28Å; V146-S148 PolarHBondContact O-N 2.94Å; V146-I149 PolarHBondContact O-N 3.46Å; V146-E150 WeakPolarHBondContact O-CB 3.17Å; V146-E150 PolarHBondContact O-N 2.78Å
147	I	94.8	Very high	93.1	Very high	55 Å²	55	55.9 Å²	55.9	28%	0.282	31%	0.307	S	S	.	.	H	α-helix	trans	-56.5	-44.2	177.7	-68.1	166.8	0	0	0	111	V143 Q144 Y151 L178 Y181	V143-I147 HydrophobicContact CG1-CD1 3.96Å; V143-I147 VanDerWaalsContact O-CG1 3.31Å; V143-I147 WeakPolarHBondContact O-CG1 3.3Å; V143-I147 PolarHBondContact O-N 3.32Å; Q144-I147 PolarHBondContact O-N 2.89Å; I147-Y151 WeakPolarHBondContact O-CB 3.49Å; I147-Y151 PolarHBondContact O-N 2.87Å; I147-Y151 VanDerWaalsContact O-N 3.09Å; I147-L178 HydrophobicContact CG2-CD2 4.2Å; I147-Y181 HydrophobicContact CD1-CG 4.23Å
148	S	93.5	Very high	92.5	Very high	4 Å²	4	61.6 Å²	61.6	3%	0.028	34%	0.338	C	S	.	.	H	α-helix	trans	-70.3	-38.5	-177.1	-51.6	0	0	0	0	112	Q144 I145 V146 L152	Q144-S148 PolarHBondContact NE2-OG 3.22Å; Q144-S148 VanDerWaalsContact O-CB 3.32Å; Q144-S148 WeakPolarHBondContact O-CB 3.36Å; Q144-S148 PolarHBondContact O-N 3.45Å; Q144-S148 PolarHBondContact O-OG 3.49Å; I145-S148 PolarHBondContact O-N 3.3Å; V146-S148 VanDerWaalsContact C-N 3.28Å; V146-S148 PolarHBondContact O-N 2.94Å; S148-L152 WeakPolarHBondContact O-CB 3.38Å; S148-L152 WeakPolarHBondContact O-CG 3.36Å; S148-L152 PolarHBondContact O-N 2.9Å; S148-L152 VanDerWaalsContact O-N 3.11Å
149	I	92.6	Very high	92	Very high	84 Å²	84	61 Å²	61	43%	0.431	33%	0.333	S	S	.	.	H	α-helix	trans	-66.8	-48.4	175.4	-69.8	172.7	0	0	0	110.3	F98 I145 V146 Y151 L152 V153	F98-I149 HydrophobicContact CE2-CG1 3.89Å; I145-I149 HydrophobicContact CG2-CD1 3.63Å; I145-I149 HydrophobicContact CG2-CG1 4.3Å; I145-I149 WeakPolarHBondContact O-CB 3.41Å; I145-I149 VanDerWaalsContact O-CG1 3.26Å; I145-I149 WeakPolarHBondContact O-CG1 3.17Å; I145-I149 PolarHBondContact O-N 3.38Å; V146-I149 PolarHBondContact O-N 3.46Å; I149-Y151 VanDerWaalsContact C-N 3.33Å; I149-Y151 PolarHBondContact O-N 2.95Å; I149-L152 PolarHBondContact O-N 3.48Å; I149-V153 HydrophobicContact CG2-CG2 3.97Å; I149-V153 WeakPolarHBondContact O-CB 3.26Å; I149-V153 VanDerWaalsContact O-CG2 3.27Å; I149-V153 WeakPolarHBondContact O-CG2 3.44Å; I149-V153 PolarHBondContact O-N 2.94Å
150	E	93.2	Very high	91.3	Very high	125 Å²	125	65.6 Å²	65.6	58%	0.584	34%	0.34	S	S	*	.	H	α-helix	trans	-58.4	-46.2	-178.6	-174	-177.2	168.7	0	0	111.2	V146 T154	V146-E150 WeakPolarHBondContact O-CB 3.17Å; V146-E150 PolarHBondContact O-N 2.78Å; E150-T154 VanDerWaalsContact O-CB 3.28Å; E150-T154 WeakPolarHBondContact O-CB 3.45Å; E150-T154 PolarHBondContact O-N 3.31Å; E150-T154 PolarHBondContact O-OG1 3.44Å
151	Y	91.1	Very high	90.5	Very high	35 Å²	35	68.6 Å²	68.6	14%	0.137	36%	0.359	C	S	.	.	H	α-helix	trans	-60.4	-49.3	175.3	178.9	-93.7	0	0	0	112.4	F97 I147 I149 T154 M155 F163 L178	F97-Y151 HydrophobicContact CD1-CE1 4.06Å; I147-Y151 WeakPolarHBondContact O-CB 3.49Å; I147-Y151 PolarHBondContact O-N 2.87Å; I147-Y151 VanDerWaalsContact O-N 3.09Å; I149-Y151 VanDerWaalsContact C-N 3.33Å; I149-Y151 PolarHBondContact O-N 2.95Å; Y151-T154 PolarHBondContact O-N 3.49Å; Y151-M155 HydrophobicContact CD1-CG 4.24Å; Y151-M155 HydrophobicContact CD2-CE 4.47Å; Y151-M155 HydrophobicContact CD2-CG 4.3Å; Y151-M155 HydrophobicContact CE1-CG 3.84Å; Y151-M155 HydrophobicContact CE2-CE 3.83Å; Y151-M155 HydrophobicContact CE2-CG 3.94Å; Y151-M155 HydrophobicContact CG-CG 4.46Å; Y151-M155 WeakPolarHBondContact O-CB 3.1Å; Y151-M155 WeakPolarHBondContact O-CG 3.4Å; Y151-M155 PolarHBondContact O-N 3.28Å; Y151-F163 HydrophobicContact CE1-CE2 4.26Å; Y151-L178 VanDerWaalsContact CB-CD2 3.46Å; Y151-L178 HydrophobicContact CD1-CD1 3.51Å; Y151-L178 HydrophobicContact CD1-CD2 4.01Å; Y151-L178 HydrophobicContact CD1-CG 4.33Å; Y151-L178 HydrophobicContact CD2-CD1 4.06Å; Y151-L178 HydrophobicContact CD2-CD2 3.68Å; Y151-L178 HydrophobicContact CD2-CG 4.16Å; Y151-L178 HydrophobicContact CE1-CD1 3.53Å; Y151-L178 HydrophobicContact CE2-CD1 4.06Å; Y151-L178 HydrophobicContact CE2-CD2 4.4Å; Y151-L178 HydrophobicContact CE2-CG 4.41Å; Y151-L178 HydrophobicContact CG-CD1 3.78Å; Y151-L178 HydrophobicContact CG-CD2 3.43Å; Y151-L178 VanDerWaalsContact CG-CD2 3.43Å; Y151-L178 HydrophobicContact CG-CG 4.11Å
152	L	88.9	Confident	89.8	Confident	24 Å²	24	72 Å²	72	13%	0.126	38%	0.375	C	S	.	.	H	α-helix	trans	-63.6	-44.6	-179.4	-82.7	-169.4	0	0	0	112.3	S94 F98 S148 I149 T154 M155 L156	S94-L152 WeakPolarHBondContact OG-CD1 3.5Å; S94-L152 WeakPolarHBondContact OG-CD2 3.47Å; F98-L152 HydrophobicContact CB-CD1 3.63Å; F98-L152 HydrophobicContact CD2-CD1 4.06Å; F98-L152 HydrophobicContact CG-CD1 4.11Å; S148-L152 WeakPolarHBondContact O-CB 3.38Å; S148-L152 WeakPolarHBondContact O-CG 3.36Å; S148-L152 PolarHBondContact O-N 2.9Å; S148-L152 VanDerWaalsContact O-N 3.11Å; I149-L152 PolarHBondContact O-N 3.48Å; L152-T154 VanDerWaalsContact C-N 3.31Å; L152-T154 PolarHBondContact O-N 3.04Å; L152-M155 PolarHBondContact O-N 3.16Å; L152-L156 WeakPolarHBondContact O-CB 3.33Å; L152-L156 PolarHBondContact O-N 3.22Å
153	V	90.6	Very high	89	Confident	80 Å²	80	68 Å²	68	49%	0.485	35%	0.354	S	S	.	.	H	α-helix	trans	-60.9	-45.1	177.8	170.3	0	0	0	0	109.7	I149 M155 V157	I149-V153 HydrophobicContact CG2-CG2 3.97Å; I149-V153 WeakPolarHBondContact O-CB 3.26Å; I149-V153 VanDerWaalsContact O-CG2 3.27Å; I149-V153 WeakPolarHBondContact O-CG2 3.44Å; I149-V153 PolarHBondContact O-N 2.94Å; V153-M155 PolarHBondContact O-N 2.99Å; V153-V157 HydrophobicContact CG1-CG2 4.13Å; V153-V157 WeakPolarHBondContact O-CB 3.44Å; V153-V157 VanDerWaalsContact O-CG2 3.3Å; V153-V157 WeakPolarHBondContact O-CG2 3.33Å; V153-V157 PolarHBondContact O-N 2.96Å
154	T	88.6	Confident	88.1	Confident	60 Å²	60	66.9 Å²	66.9	37%	0.368	35%	0.346	S	S	.	.	I	π-helix	trans	-61.5	-48.1	178.7	-57.6	0	0	0	0	111.1	E150 Y151 L152 N158 Q159	E150-T154 VanDerWaalsContact O-CB 3.28Å; E150-T154 WeakPolarHBondContact O-CB 3.45Å; E150-T154 PolarHBondContact O-N 3.31Å; E150-T154 PolarHBondContact O-OG1 3.44Å; Y151-T154 PolarHBondContact O-N 3.49Å; L152-T154 VanDerWaalsContact C-N 3.31Å; L152-T154 PolarHBondContact O-N 3.04Å; T154-N158 WeakPolarHBondContact O-CB 3.47Å; T154-N158 PolarHBondContact O-N 3.4Å; T154-Q159 PolarHBondContact O-N 3.04Å
155	M	86.6	Confident	87.2	Confident	22 Å²	22	73.1 Å²	73.1	11%	0.108	38%	0.379	C	S	.	.	I	π-helix	trans	-70.9	-38.4	-177.7	-72.1	-64.7	159.4	0	0	112.9	Y151 L152 V153 Q159 R160 F163	Y151-M155 HydrophobicContact CD1-CG 4.24Å; Y151-M155 HydrophobicContact CD2-CE 4.47Å; Y151-M155 HydrophobicContact CD2-CG 4.3Å; Y151-M155 HydrophobicContact CE1-CG 3.84Å; Y151-M155 HydrophobicContact CE2-CE 3.83Å; Y151-M155 HydrophobicContact CE2-CG 3.94Å; Y151-M155 HydrophobicContact CG-CG 4.46Å; Y151-M155 WeakPolarHBondContact O-CB 3.1Å; Y151-M155 WeakPolarHBondContact O-CG 3.4Å; Y151-M155 PolarHBondContact O-N 3.28Å; L152-M155 PolarHBondContact O-N 3.16Å; V153-M155 PolarHBondContact O-N 2.99Å; M155-Q159 CarbonylContact O-C 3Å; M155-Q159 PolarHBondContact O-N 3.41Å; M155-Q159 HydrophobicContact SD-CB 4.48Å; M155-R160 WeakPolarHBondContact O-CA 3.36Å; M155-R160 PolarHBondContact O-N 3.43Å; M155-R160 VanDerWaalsContact O-N 3.07Å; M155-F163 HydrophobicContact CB-CB 4.22Å; M155-F163 HydrophobicContact CB-CD2 3.67Å; M155-F163 HydrophobicContact CB-CE2 4.22Å; M155-F163 HydrophobicContact CB-CG 3.99Å; M155-F163 HydrophobicContact CG-CD2 3.98Å; M155-F163 HydrophobicContact CG-CE2 4.5Å; M155-F163 HydrophobicContact SD-CD2 4.3Å
156	L	85.7	Confident	86.4	Confident	83 Å²	83	71.9 Å²	71.9	44%	0.435	37%	0.373	S	S	.	.	I	π-helix	trans	-83.9	-33.9	-174.5	-153.7	74.2	0	0	0	113	L152	L152-L156 WeakPolarHBondContact O-CB 3.33Å; L152-L156 PolarHBondContact O-N 3.22Å
157	V	86.8	Confident	85.7	Confident	119 Å²	119	72.3 Å²	72.3	72%	0.721	38%	0.377	S	S	*	.	I	π-helix	trans	-88.3	-46.6	-179.5	-179.5	0	0	0	0	111.1	V153	V153-V157 HydrophobicContact CG1-CG2 4.13Å; V153-V157 WeakPolarHBondContact O-CB 3.44Å; V153-V157 VanDerWaalsContact O-CG2 3.3Å; V153-V157 WeakPolarHBondContact O-CG2 3.33Å; V153-V157 PolarHBondContact O-N 2.96Å
158	N	84.1	Confident	84.8	Confident	124 Å²	124	72.3 Å²	72.3	66%	0.663	39%	0.385	S	S	*	.	I	π-helix	trans	-93.9	-30.8	-170.5	-165.4	46.8	0	0	0	113.2	T154	T154-N158 WeakPolarHBondContact O-CB 3.47Å; T154-N158 PolarHBondContact O-N 3.4Å
159	Q	84.3	Confident	84.1	Confident	70 Å²	70	78 Å²	78	33%	0.327	41%	0.411	S	S	.	.			trans	-135.1	37.5	-168.3	-66.6	-166.9	-36.6	0	0	113.4	T154 M155 D161 I162 F163	T154-Q159 PolarHBondContact O-N 3.04Å; M155-Q159 CarbonylContact O-C 3Å; M155-Q159 PolarHBondContact O-N 3.41Å; M155-Q159 HydrophobicContact SD-CB 4.48Å; Q159-D161 PolarHBondContact O-N 3.03Å; Q159-I162 HydrophobicContact CB-CB 4.24Å; Q159-I162 HydrophobicContact CB-CD1 4.22Å; Q159-I162 HydrophobicContact CG-CD1 4.18Å; Q159-I162 WeakPolarHBondContact O-CB 3.27Å; Q159-I162 PolarHBondContact O-N 3.4Å; Q159-I162 VanDerWaalsContact O-N 3.07Å; Q159-F163 PolarHBondContact O-N 2.91Å
160	R	82.2	Confident	83.7	Confident	143 Å²	143	78.9 Å²	78.9	54%	0.54	41%	0.412	S	S	.	.	H	α-helix	trans	-54.4	-48.4	-172.6	-169.8	179.4	178.5	-174.5	-1.2	113.3	M155 I162 F163 L164	M155-R160 WeakPolarHBondContact O-CA 3.36Å; M155-R160 PolarHBondContact O-N 3.43Å; M155-R160 VanDerWaalsContact O-N 3.07Å; R160-I162 VanDerWaalsContact C-N 3.28Å; R160-I162 PolarHBondContact O-N 3.28Å; R160-F163 PolarHBondContact O-N 3.17Å; R160-L164 HydrophobicContact CG-CD1 4.14Å; R160-L164 WeakPolarHBondContact O-CG 3.28Å; R160-L164 PolarHBondContact O-N 3.46Å
161	D	80.4	Confident	83.2	Confident	122 Å²	122	74.1 Å²	74.1	65%	0.652	39%	0.392	S	S	*	.	H	α-helix	trans	-66.2	-33.1	-178.2	-62.8	-44.6	0	0	0	112.3	Q159 N165	Q159-D161 PolarHBondContact O-N 3.03Å; D161-N165 WeakPolarHBondContact O-CB 3.27Å; D161-N165 PolarHBondContact O-N 2.89Å; D161-N165 VanDerWaalsContact O-N 3.13Å; D161-N165 PolarHBondContact O-ND2 3.25Å
162	I	80.5	Confident	82.9	Confident	84 Å²	84	73.4 Å²	73.4	43%	0.431	39%	0.39	S	S	.	.	H	α-helix	trans	-71.4	-40.9	175.9	-58.9	173.4	0	0	0	109.8	Q159 R160 M166	Q159-I162 HydrophobicContact CB-CB 4.24Å; Q159-I162 HydrophobicContact CB-CD1 4.22Å; Q159-I162 HydrophobicContact CG-CD1 4.18Å; Q159-I162 WeakPolarHBondContact O-CB 3.27Å; Q159-I162 PolarHBondContact O-N 3.4Å; Q159-I162 VanDerWaalsContact O-N 3.07Å; R160-I162 VanDerWaalsContact C-N 3.28Å; R160-I162 PolarHBondContact O-N 3.28Å; I162-M166 HydrophobicContact CG2-CE 4.2Å; I162-M166 WeakPolarHBondContact O-CA 3.44Å; I162-M166 WeakPolarHBondContact O-CB 3.36Å; I162-M166 PolarHBondContact O-N 3Å
163	F	79.6	Confident	82.8	Confident	8 Å²	8	77.1 Å²	77.1	4%	0.035	41%	0.405	C	S	.	.	H	α-helix	trans	-66.1	-38.5	178.7	-178.1	-106.7	0	0	0	112.5	R93 Y151 M155 Q159 R160	R93-F163 HydrophobicContact CG-CE1 4.24Å; R93-F163 HydrophobicContact CG-CZ 4.12Å; R93-F163 PolarHBondContact NH1-O 3.31Å; Y151-F163 HydrophobicContact CE1-CE2 4.26Å; M155-F163 HydrophobicContact CB-CB 4.22Å; M155-F163 HydrophobicContact CB-CD2 3.67Å; M155-F163 HydrophobicContact CB-CE2 4.22Å; M155-F163 HydrophobicContact CB-CG 3.99Å; M155-F163 HydrophobicContact CG-CD2 3.98Å; M155-F163 HydrophobicContact CG-CE2 4.5Å; M155-F163 HydrophobicContact SD-CD2 4.3Å; Q159-F163 PolarHBondContact O-N 2.91Å; R160-F163 PolarHBondContact O-N 3.17Å
164	L	77.3	Confident	82.7	Confident	39 Å²	39	74.5 Å²	74.5	20%	0.204	39%	0.388	C	S	.	.	H	α-helix	trans	-74.2	-36	178.6	-67.6	179.2	0	0	0	112.7	D90 R93 R160	D90-L164 HydrophobicContact CB-CD2 4.47Å; D90-L164 WeakPolarHBondContact OD1-CD2 3.27Å; R93-L164 VanDerWaalsContact NH1-C 3.33Å; R93-L164 VanDerWaalsContact NH1-CA 3.34Å; R93-L164 PolarHBondContact NH1-O 3.29Å; R160-L164 HydrophobicContact CG-CD1 4.14Å; R160-L164 WeakPolarHBondContact O-CG 3.28Å; R160-L164 PolarHBondContact O-N 3.46Å
165	N	79.4	Confident	82.7	Confident	131 Å²	131	71.9 Å²	71.9	70%	0.701	37%	0.372	S	S	*	.	T	Hydrogen-bonded Turn	trans	-101.2	15.5	-176.8	-60.2	-55.6	0	0	0	114.1	D161	D161-N165 WeakPolarHBondContact O-CB 3.27Å; D161-N165 PolarHBondContact O-N 2.89Å; D161-N165 VanDerWaalsContact O-N 3.13Å; D161-N165 PolarHBondContact O-ND2 3.25Å
166	M	78.8	Confident	82.9	Confident	21 Å²	21	72 Å²	72	10%	0.103	37%	0.374	C	S	.	.			trans	-66.7	135.6	-177	-165.9	170.9	-76.5	0	0	111.5	I162 K170 T171	I162-M166 HydrophobicContact CG2-CE 4.2Å; I162-M166 WeakPolarHBondContact O-CA 3.44Å; I162-M166 WeakPolarHBondContact O-CB 3.36Å; I162-M166 PolarHBondContact O-N 3Å; M166-K170 HydrophobicContact CE-CD 4.07Å; M166-K170 HydrophobicContact CE-CG 4.42Å; M166-K170 HydrophobicContact CG-CB 3.87Å; M166-K170 HydrophobicContact CG-CD 4.02Å; M166-K170 HydrophobicContact CG-CG 4.08Å; M166-K170 HydrophobicContact SD-CB 4Å; M166-K170 HydrophobicContact SD-CD 3.9Å; M166-K170 HydrophobicContact SD-CG 3.68Å; M166-T171 WeakPolarHBondContact CB-OG1 3.36Å; M166-T171 WeakPolarHBondContact CG-OG1 3.14Å
167	P	81.1	Confident	83.2	Confident	86 Å²	86	74.4 Å²	74.4	56%	0.558	38%	0.384	S	S	*	.			trans	-65.3	141.2	172.9	25.3	-33.2	0	0	0	111.1	E169 K170 T171	P167-E169 PolarHBondContact O-N 3.29Å; P167-E169 VanDerWaalsContact O-N 3.1Å; P167-K170 HydrophobicContact CG-CB 4.07Å; P167-K170 PolarHBondContact O-N 3.3Å; P167-T171 PolarHBondContact O-N 3.46Å; P167-T171 VanDerWaalsContact O-N 3.11Å; P167-T171 PolarHBondContact O-OG1 3.44Å
168	A	75.4	Confident	83.4	Confident	55 Å²	55	69.6 Å²	69.6	46%	0.455	36%	0.355	S	S	.	.	H	α-helix	trans	-51.8	-38.4	-175	0	0	0	0	0	113.6	K170 T171 N172	A168-K170 VanDerWaalsContact C-N 3.34Å; A168-K170 PolarHBondContact O-N 2.8Å; A168-T171 PolarHBondContact O-N 2.84Å; A168-N172 WeakPolarHBondContact O-CB 3.32Å; A168-N172 PolarHBondContact O-N 2.84Å; A168-N172 PolarHBondContact O-OD1 3.25Å
169	E	79.8	Confident	83.9	Confident	122 Å²	122	63.9 Å²	63.9	57%	0.57	32%	0.324	S	S	*	.	H	α-helix	trans	-61	-41.3	178	-171.8	-172.4	159.8	0	0	112.6	P167 K173	P167-E169 PolarHBondContact O-N 3.29Å; P167-E169 VanDerWaalsContact O-N 3.1Å; E169-K173 WeakPolarHBondContact O-CG 3.23Å; E169-K173 PolarHBondContact O-N 3.47Å; E169-K173 WeakPolarHBondContact OE1-CE 3.36Å; E169-K173 IonicContact OE1-NZ 2.66Å; E169-K173 PolarHBondContact OE1-NZ 2.94Å
170	K	82.4	Confident	84.4	Confident	104 Å²	104	65.9 Å²	65.9	45%	0.452	34%	0.336	S	S	.	.	H	α-helix	trans	-72.2	-42	178.9	-172.6	177.4	176.8	178.9	0	110.4	M166 P167 A168 N172 K173 D174	M166-K170 HydrophobicContact CE-CD 4.07Å; M166-K170 HydrophobicContact CE-CG 4.42Å; M166-K170 HydrophobicContact CG-CB 3.87Å; M166-K170 HydrophobicContact CG-CD 4.02Å; M166-K170 HydrophobicContact CG-CG 4.08Å; M166-K170 HydrophobicContact SD-CB 4Å; M166-K170 HydrophobicContact SD-CD 3.9Å; M166-K170 HydrophobicContact SD-CG 3.68Å; P167-K170 HydrophobicContact CG-CB 4.07Å; P167-K170 PolarHBondContact O-N 3.3Å; A168-K170 VanDerWaalsContact C-N 3.34Å; A168-K170 PolarHBondContact O-N 2.8Å; K170-N172 VanDerWaalsContact C-N 3.31Å; K170-N172 PolarHBondContact O-N 2.95Å; K170-K173 PolarHBondContact O-N 3.47Å; K170-D174 PolarHBondContact O-N 3.06Å
171	T	83.1	Confident	85.1	Confident	25 Å²	25	60.8 Å²	60.8	15%	0.153	32%	0.317	C	S	.	.	H	α-helix	trans	-56.5	-43.5	174.5	-58	0	0	0	0	112.1	F97 M166 P167 A168 D174 F175	F97-T171 HydrophobicContact CE2-CG2 4.08Å; F97-T171 HydrophobicContact CZ-CG2 3.5Å; F97-T171 VanDerWaalsContact CZ-CG2 3.5Å; M166-T171 WeakPolarHBondContact CB-OG1 3.36Å; M166-T171 WeakPolarHBondContact CG-OG1 3.14Å; P167-T171 PolarHBondContact O-N 3.46Å; P167-T171 VanDerWaalsContact O-N 3.11Å; P167-T171 PolarHBondContact O-OG1 3.44Å; A168-T171 PolarHBondContact O-N 2.84Å; T171-D174 PolarHBondContact O-N 3.48Å; T171-F175 VanDerWaalsContact O-CB 3.26Å; T171-F175 WeakPolarHBondContact O-CB 3.4Å; T171-F175 PolarHBondContact O-N 3.25Å
172	N	85.3	Confident	85.9	Confident	20 Å²	20	55 Å²	55	11%	0.107	29%	0.286	C	S	.	.	H	α-helix	trans	-67.3	-37.8	178.9	-69.9	-6.2	0	0	0	112.3	A168 K170 V176 L229 D242	A168-N172 WeakPolarHBondContact O-CB 3.32Å; A168-N172 PolarHBondContact O-N 2.84Å; A168-N172 PolarHBondContact O-OD1 3.25Å; K170-N172 VanDerWaalsContact C-N 3.31Å; K170-N172 PolarHBondContact O-N 2.95Å; N172-V176 WeakPolarHBondContact O-CG2 3.28Å; N172-V176 PolarHBondContact O-N 3.32Å; N172-V176 VanDerWaalsContact O-N 3.09Å; N172-L229 HydrophobicContact CB-CD2 4.01Å; N172-L229 HydrophobicContact CB-CG 3.94Å; N172-L229 PolarHBondContact ND2-O 2.97Å; N172-D242 PolarHBondContact ND2-OD1 3.27Å; N172-D242 PolarHBondContact ND2-OD2 3.19Å
173	K	86.8	Confident	86.6	Confident	101 Å²	101	53.3 Å²	53.3	44%	0.439	28%	0.277	S	S	.	.	H	α-helix	trans	-66.8	-46.5	175	-72.4	173.3	-171.2	164.2	0	111.7	E169 K170 F175 V176 M177	E169-K173 WeakPolarHBondContact O-CG 3.23Å; E169-K173 PolarHBondContact O-N 3.47Å; E169-K173 WeakPolarHBondContact OE1-CE 3.36Å; E169-K173 IonicContact OE1-NZ 2.66Å; E169-K173 PolarHBondContact OE1-NZ 2.94Å; K170-K173 PolarHBondContact O-N 3.47Å; K173-F175 VanDerWaalsContact C-N 3.28Å; K173-F175 PolarHBondContact O-N 3.09Å; K173-V176 PolarHBondContact O-N 2.86Å; K173-M177 WeakPolarHBondContact O-CB 3.21Å; K173-M177 PolarHBondContact O-N 2.97Å
174	D	88.2	Confident	87.5	Confident	25 Å²	25	58.5 Å²	58.5	13%	0.134	30%	0.3	C	S	.	.	H	α-helix	trans	-63.1	-38.6	177.6	-73.1	2.6	0	0	0	110.7	K170 T171 M177 L178	K170-D174 PolarHBondContact O-N 3.06Å; T171-D174 PolarHBondContact O-N 3.48Å; D174-M177 WeakPolarHBondContact O-CB 3.46Å; D174-M177 PolarHBondContact O-N 3.33Å; D174-L178 WeakPolarHBondContact O-CG 3.44Å; D174-L178 PolarHBondContact O-N 3.34Å
175	F	88.6	Confident	88.4	Confident	6 Å²	6	56.7 Å²	56.7	3%	0.026	29%	0.291	C	S	.	.	H	α-helix	trans	-59.5	-48.8	174.2	-176.3	-109.1	0	0	0	112.2	F97 F100 T171 K173 M177 L178 L179 W225 L229 L246	F97-F175 HydrophobicContact CD1-CB 4.49Å; F97-F175 AromaticContact CD1-CD2 3.81Å; F97-F175 HydrophobicContact CD1-CD2 3.81Å; F97-F175 HydrophobicContact CD2-CD2 4.25Å; F97-F175 HydrophobicContact CE1-CB 3.65Å; F97-F175 AromaticContact CE1-CD2 3.7Å; F97-F175 HydrophobicContact CE1-CD2 3.7Å; F97-F175 HydrophobicContact CE1-CG 4.17Å; F97-F175 HydrophobicContact CE2-CD2 4.15Å; F97-F175 HydrophobicContact CG-CD2 4.07Å; F97-F175 HydrophobicContact CZ-CB 3.81Å; F97-F175 AromaticContact CZ-CD2 3.85Å; F97-F175 HydrophobicContact CZ-CD2 3.85Å; F97-F175 HydrophobicContact CZ-CG 4.22Å; F100-F175 HydrophobicContact CB-CE2 4.1Å; F100-F175 HydrophobicContact CB-CZ 4.01Å; F100-F175 HydrophobicContact CD1-CE1 4.36Å; F100-F175 HydrophobicContact CD1-CE2 4.34Å; F100-F175 AromaticContact CD1-CZ 3.62Å; F100-F175 HydrophobicContact CD1-CZ 3.62Å; F100-F175 AromaticContact CD2-CZ 3.83Å; F100-F175 HydrophobicContact CD2-CZ 3.83Å; F100-F175 HydrophobicContact CE1-CE1 4.26Å; F100-F175 AromaticContact CE1-CZ 3.94Å; F100-F175 HydrophobicContact CE1-CZ 3.94Å; F100-F175 HydrophobicContact CE2-CZ 4.12Å; F100-F175 HydrophobicContact CG-CE2 4.16Å; F100-F175 AromaticContact CG-CZ 3.55Å; F100-F175 HydrophobicContact CG-CZ 3.55Å; F100-F175 HydrophobicContact CZ-CE1 4.38Å; F100-F175 HydrophobicContact CZ-CZ 4.17Å; T171-F175 VanDerWaalsContact O-CB 3.26Å; T171-F175 WeakPolarHBondContact O-CB 3.4Å; T171-F175 PolarHBondContact O-N 3.25Å; K173-F175 VanDerWaalsContact C-N 3.28Å; K173-F175 PolarHBondContact O-N 3.09Å; F175-M177 VanDerWaalsContact C-N 3.33Å; F175-M177 PolarHBondContact O-N 3.45Å; F175-L178 PolarHBondContact O-N 2.93Å; F175-L179 HydrophobicContact CD1-CD1 4.13Å; F175-L179 HydrophobicContact CE1-CD1 3.77Å; F175-L179 HydrophobicContact CZ-CD1 4.03Å; F175-L179 WeakPolarHBondContact O-CG 3.28Å; F175-W225 HydrophobicContact CD1-CH2 4.13Å; F175-W225 HydrophobicContact CD1-CZ3 4.14Å; F175-W225 AromaticContact CE1-CH2 3.63Å; F175-W225 HydrophobicContact CE1-CH2 3.63Å; F175-W225 AromaticContact CE1-CZ3 3.77Å; F175-W225 HydrophobicContact CE1-CZ3 3.77Å; F175-L229 HydrophobicContact CD1-CD2 3.87Å; F175-L229 HydrophobicContact CE1-CD2 4.49Å; F175-L246 HydrophobicContact CE1-CD1 4.3Å; F175-L246 HydrophobicContact CE1-CD2 3.78Å; F175-L246 HydrophobicContact CZ-CD2 4.41Å
176	V	91.3	Very high	89.2	Confident	23 Å²	23	50.7 Å²	50.7	14%	0.139	26%	0.259	C	S	.	.	H	α-helix	trans	-66.2	-37	177.5	175	0	0	0	0	111.4	N172 K173 L178 L179 W225 I226 L229 I230	N172-V176 WeakPolarHBondContact O-CG2 3.28Å; N172-V176 PolarHBondContact O-N 3.32Å; N172-V176 VanDerWaalsContact O-N 3.09Å; K173-V176 PolarHBondContact O-N 2.86Å; V176-L178 VanDerWaalsContact C-N 3.29Å; V176-L178 PolarHBondContact O-N 3.35Å; V176-L179 PolarHBondContact O-N 3.28Å; V176-W225 HydrophobicContact CG2-CZ3 4.46Å; V176-I226 HydrophobicContact CG1-CD1 4.35Å; V176-I226 HydrophobicContact CG1-CG2 4.15Å; V176-I226 HydrophobicContact CG2-CG1 4.41Å; V176-I226 HydrophobicContact CG2-CG2 4.34Å; V176-L229 HydrophobicContact CG2-CD2 4.08Å; V176-I230 HydrophobicContact CG1-CD1 4.39Å; V176-I230 HydrophobicContact CG2-CD1 4.22Å; V176-I230 HydrophobicContact CG2-CG1 4.35Å
177	M	91	Very high	90	Very high	134 Å²	134	51.9 Å²	51.9	66%	0.66	27%	0.272	S	S	*	.	H	α-helix	trans	-58.9	-41.2	176.8	-171	-173.3	-60.8	0	0	111.7	K173 D174 F175 L179 I180	K173-M177 WeakPolarHBondContact O-CB 3.21Å; K173-M177 PolarHBondContact O-N 2.97Å; D174-M177 WeakPolarHBondContact O-CB 3.46Å; D174-M177 PolarHBondContact O-N 3.33Å; F175-M177 VanDerWaalsContact C-N 3.33Å; F175-M177 PolarHBondContact O-N 3.45Å; M177-L179 PolarHBondContact O-N 3.23Å; M177-I180 WeakPolarHBondContact O-CB 3.38Å; M177-I180 VanDerWaalsContact O-CG2 3.27Å; M177-I180 WeakPolarHBondContact O-CG2 3.46Å; M177-I180 PolarHBondContact O-N 3.07Å
178	L	92.3	Very high	90.8	Very high	19 Å²	19	50.4 Å²	50.4	10%	0.099	26%	0.259	C	S	.	.	H	α-helix	trans	-64.3	-19.5	177	-73.2	163.5	0	0	0	114.2	F97 Q144 I147 Y151 D174 F175 V176	F97-L178 HydrophobicContact CD1-CD1 3.7Å; F97-L178 HydrophobicContact CE1-CD1 4.3Å; Q144-L178 PolarHBondContact NE2-O 2.99Å; I147-L178 HydrophobicContact CG2-CD2 4.2Å; Y151-L178 VanDerWaalsContact CB-CD2 3.46Å; Y151-L178 HydrophobicContact CD1-CD1 3.51Å; Y151-L178 HydrophobicContact CD1-CD2 4.01Å; Y151-L178 HydrophobicContact CD1-CG 4.33Å; Y151-L178 HydrophobicContact CD2-CD1 4.06Å; Y151-L178 HydrophobicContact CD2-CD2 3.68Å; Y151-L178 HydrophobicContact CD2-CG 4.16Å; Y151-L178 HydrophobicContact CE1-CD1 3.53Å; Y151-L178 HydrophobicContact CE2-CD1 4.06Å; Y151-L178 HydrophobicContact CE2-CD2 4.4Å; Y151-L178 HydrophobicContact CE2-CG 4.41Å; Y151-L178 HydrophobicContact CG-CD1 3.78Å; Y151-L178 HydrophobicContact CG-CD2 3.43Å; Y151-L178 VanDerWaalsContact CG-CD2 3.43Å; Y151-L178 HydrophobicContact CG-CG 4.11Å; D174-L178 WeakPolarHBondContact O-CG 3.44Å; D174-L178 PolarHBondContact O-N 3.34Å; F175-L178 PolarHBondContact O-N 2.93Å; V176-L178 VanDerWaalsContact C-N 3.29Å; V176-L178 PolarHBondContact O-N 3.35Å
179	L	94.3	Very high	91.7	Very high	3 Å²	3	47.8 Å²	47.8	2%	0.016	24%	0.237	C	C	.	.	T	Hydrogen-bonded Turn	trans	-97	5.1	-178.3	-57.3	171.6	0	0	0	112.6	F100 G101 F175 V176 M177 Y181 V182 L183 W222 W225	F100-L179 HydrophobicContact CD1-CD1 3.78Å; F100-L179 HydrophobicContact CD1-CD2 3.74Å; F100-L179 HydrophobicContact CD1-CG 4.42Å; F100-L179 HydrophobicContact CE1-CD1 3.59Å; F100-L179 HydrophobicContact CE1-CD2 4.24Å; G101-L179 VanDerWaalsContact CA-CD2 3.44Å; F175-L179 HydrophobicContact CD1-CD1 4.13Å; F175-L179 HydrophobicContact CE1-CD1 3.77Å; F175-L179 HydrophobicContact CZ-CD1 4.03Å; F175-L179 WeakPolarHBondContact O-CG 3.28Å; V176-L179 PolarHBondContact O-N 3.28Å; M177-L179 PolarHBondContact O-N 3.23Å; L179-Y181 PolarHBondContact O-N 2.7Å; L179-V182 HydrophobicContact CD2-CG2 4.14Å; L179-V182 WeakPolarHBondContact O-CA 3.33Å; L179-V182 WeakPolarHBondContact O-CB 3.44Å; L179-V182 PolarHBondContact O-N 3Å; L179-L183 WeakPolarHBondContact O-CG 3.23Å; L179-L183 PolarHBondContact O-N 3.19Å; L179-W222 HydrophobicContact CB-CH2 4.16Å; L179-W222 HydrophobicContact CB-CZ3 3.9Å; L179-W222 HydrophobicContact CD1-CH2 4.06Å; L179-W222 HydrophobicContact CD1-CZ3 3.96Å; L179-W222 HydrophobicContact CD2-CH2 4.33Å; L179-W222 HydrophobicContact CG-CH2 4.41Å; L179-W222 HydrophobicContact CG-CZ3 4.44Å; L179-W225 HydrophobicContact CD1-CH2 3.55Å; L179-W225 HydrophobicContact CD1-CZ2 3.91Å
180	I	94.9	Very high	92.5	Very high	113 Å²	113	44.7 Å²	44.7	58%	0.579	22%	0.222	S	C	*	.	H	α-helix	trans	-58.7	-38.1	-179.9	-164.3	63.6	0	0	0	112.3	M177 L183 F184	M177-I180 WeakPolarHBondContact O-CB 3.38Å; M177-I180 VanDerWaalsContact O-CG2 3.27Å; M177-I180 WeakPolarHBondContact O-CG2 3.46Å; M177-I180 PolarHBondContact O-N 3.07Å; I180-L183 HydrophobicContact CD1-CD1 4.38Å; I180-L183 WeakPolarHBondContact O-CB 3.27Å; I180-L183 PolarHBondContact O-N 3.01Å; I180-F184 PolarHBondContact O-N 2.71Å
181	Y	96.8	Very high	93.1	Very high	35 Å²	35	44 Å²	44	14%	0.137	22%	0.223	C	C	.	.	H	α-helix	trans	-70	-37	177	177.4	-100.4	0	0	0	111.7	F140 V143 Q144 I147 L179 F184 L185	F140-Y181 VanDerWaalsContact O-CE1 3.29Å; F140-Y181 WeakPolarHBondContact O-CE1 3.29Å; F140-Y181 PolarHBondContact O-OH 2.85Å; V143-Y181 HydrophobicContact CB-CD1 4.46Å; V143-Y181 HydrophobicContact CB-CE1 3.8Å; V143-Y181 HydrophobicContact CB-CE2 3.98Å; V143-Y181 HydrophobicContact CG1-CD1 4.24Å; V143-Y181 HydrophobicContact CG1-CD2 3.8Å; V143-Y181 HydrophobicContact CG1-CE1 3.99Å; V143-Y181 HydrophobicContact CG1-CE2 3.55Å; V143-Y181 HydrophobicContact CG1-CG 4.14Å; Q144-Y181 HydrophobicContact CB-CD1 3.85Å; Q144-Y181 HydrophobicContact CB-CE1 4.14Å; I147-Y181 HydrophobicContact CD1-CG 4.23Å; L179-Y181 PolarHBondContact O-N 2.7Å; Y181-F184 HydrophobicContact CD2-CD1 4.44Å; Y181-F184 HydrophobicContact CE2-CD1 4.35Å; Y181-F184 WeakPolarHBondContact O-CB 3.39Å; Y181-F184 PolarHBondContact O-N 3.11Å; Y181-L185 HydrophobicContact CD1-CD1 4.05Å; Y181-L185 HydrophobicContact CD1-CG 4.29Å; Y181-L185 HydrophobicContact CE1-CD1 3.43Å; Y181-L185 VanDerWaalsContact CE1-CD1 3.43Å; Y181-L185 HydrophobicContact CE1-CD2 4.31Å; Y181-L185 HydrophobicContact CE1-CG 3.77Å; Y181-L185 HydrophobicContact CE2-CG 4.45Å; Y181-L185 PolarHBondContact O-N 2.94Å
182	V	96.8	Very high	93.6	Very high	0 Å²	0	43.8 Å²	43.8	0%	0	22%	0.222	C	C	.	.	H	α-helix	trans	-62.4	-43.5	172.8	-173.4	0	0	0	0	111	F104 A105 F108 Q144 L179 F184 L185 M186 W222	F104-V182 HydrophobicContact CB-CG1 3.65Å; A105-V182 HydrophobicContact CB-CG2 4.34Å; F108-V182 HydrophobicContact CD2-CG1 3.59Å; F108-V182 HydrophobicContact CE2-CG1 3.71Å; Q144-V182 HydrophobicContact CG-CG2 4.22Å; L179-V182 HydrophobicContact CD2-CG2 4.14Å; L179-V182 WeakPolarHBondContact O-CA 3.33Å; L179-V182 WeakPolarHBondContact O-CB 3.44Å; L179-V182 PolarHBondContact O-N 3Å; V182-F184 VanDerWaalsContact C-N 3.31Å; V182-F184 PolarHBondContact O-N 2.81Å; V182-L185 PolarHBondContact O-N 3.06Å; V182-M186 WeakPolarHBondContact O-CB 3.39Å; V182-M186 PolarHBondContact O-N 3.45Å; V182-W222 HydrophobicContact CB-CH2 4.08Å; V182-W222 HydrophobicContact CG1-CH2 3.59Å; V182-W222 HydrophobicContact CG1-CZ2 3.81Å; V182-W222 HydrophobicContact CG1-CZ3 4.46Å
183	L	96.1	Very high	93.9	Very high	49 Å²	49	42.9 Å²	42.9	26%	0.257	22%	0.217	S	C	.	.	H	α-helix	trans	-60.5	-41.1	173.7	-70.2	174.4	0	0	0	111.6	L179 I180 M186 A187 W222 I226	L179-L183 WeakPolarHBondContact O-CG 3.23Å; L179-L183 PolarHBondContact O-N 3.19Å; I180-L183 HydrophobicContact CD1-CD1 4.38Å; I180-L183 WeakPolarHBondContact O-CB 3.27Å; I180-L183 PolarHBondContact O-N 3.01Å; L183-M186 HydrophobicContact CD2-CE 4.07Å; L183-M186 WeakPolarHBondContact O-CB 3.35Å; L183-M186 PolarHBondContact O-N 3.31Å; L183-A187 WeakPolarHBondContact O-CB 3.39Å; L183-A187 PolarHBondContact O-N 3.18Å; L183-W222 HydrophobicContact CD2-CD2 4.31Å; L183-W222 HydrophobicContact CD2-CE3 3.49Å; L183-W222 VanDerWaalsContact CD2-CE3 3.49Å; L183-W222 HydrophobicContact CD2-CZ3 3.92Å; L183-W222 HydrophobicContact CG-CE3 4.27Å; L183-W222 HydrophobicContact CG-CZ3 4.21Å; L183-I226 HydrophobicContact CD1-CD1 4.13Å; L183-I226 HydrophobicContact CD2-CD1 4.06Å
184	F	97.2	Very high	94	Very high	118 Å²	118	42.3 Å²	42.3	52%	0.518	22%	0.217	S	C	.	.	H	α-helix	trans	-62.5	-47	174.8	173.7	-98	0	0	0	112.1	I180 Y181 V182 M186 A187 L188	I180-F184 PolarHBondContact O-N 2.71Å; Y181-F184 HydrophobicContact CD2-CD1 4.44Å; Y181-F184 HydrophobicContact CE2-CD1 4.35Å; Y181-F184 WeakPolarHBondContact O-CB 3.39Å; Y181-F184 PolarHBondContact O-N 3.11Å; V182-F184 VanDerWaalsContact C-N 3.31Å; V182-F184 PolarHBondContact O-N 2.81Å; F184-M186 VanDerWaalsContact C-N 3.26Å; F184-M186 PolarHBondContact O-N 3.47Å; F184-A187 PolarHBondContact O-N 3.48Å; F184-L188 HydrophobicContact CE1-CD2 4.17Å; F184-L188 HydrophobicContact CZ-CD2 4.36Å; F184-L188 VanDerWaalsContact O-CB 3.32Å; F184-L188 WeakPolarHBondContact O-CB 3.36Å; F184-L188 PolarHBondContact O-N 3.42Å
185	L	96.8	Very high	94	Very high	1 Å²	1	46.2 Å²	46.2	1%	0.005	23%	0.233	C	C	.	.	H	α-helix	trans	-58.4	-40.6	175	-75.6	-180	0	0	0	111.8	A105 F108 L112 F140 Y181 V182 L188 T189	A105-L185 HydrophobicContact CB-CD1 4.25Å; F108-L185 HydrophobicContact CB-CB 4.07Å; L112-L185 HydrophobicContact CD2-CD2 3.97Å; F140-L185 HydrophobicContact CB-CD2 4.22Å; F140-L185 HydrophobicContact CG-CD2 4.38Å; Y181-L185 HydrophobicContact CD1-CD1 4.05Å; Y181-L185 HydrophobicContact CD1-CG 4.29Å; Y181-L185 HydrophobicContact CE1-CD1 3.43Å; Y181-L185 VanDerWaalsContact CE1-CD1 3.43Å; Y181-L185 HydrophobicContact CE1-CD2 4.31Å; Y181-L185 HydrophobicContact CE1-CG 3.77Å; Y181-L185 HydrophobicContact CE2-CG 4.45Å; Y181-L185 PolarHBondContact O-N 2.94Å; V182-L185 PolarHBondContact O-N 3.06Å; L185-L188 PolarHBondContact O-N 3.34Å; L185-T189 WeakPolarHBondContact O-CB 3.37Å; L185-T189 PolarHBondContact O-N 2.81Å; L185-T189 PolarHBondContact O-OG1 2.74Å
186	M	95.9	Very high	93.9	Very high	4 Å²	4	46 Å²	46	2%	0.02	23%	0.232	C	C	.	.	H	α-helix	trans	-65.8	-46.2	178.7	-164.8	-168.6	-44.7	0	0	111.8	F108 V182 L183 F184 T189 F190 I215 I219 W222	F108-M186 HydrophobicContact CD1-CB 4.42Å; F108-M186 HydrophobicContact CD1-CG 4.21Å; F108-M186 HydrophobicContact CD2-CB 4.41Å; F108-M186 HydrophobicContact CD2-CE 4.47Å; F108-M186 HydrophobicContact CE1-CB 4.42Å; F108-M186 HydrophobicContact CE1-CE 4.46Å; F108-M186 HydrophobicContact CE1-CG 3.82Å; F108-M186 HydrophobicContact CE2-CB 4.39Å; F108-M186 HydrophobicContact CE2-CE 3.58Å; F108-M186 HydrophobicContact CE2-CG 4.35Å; F108-M186 HydrophobicContact CG-CB 4.45Å; F108-M186 HydrophobicContact CZ-CB 4.41Å; F108-M186 HydrophobicContact CZ-CE 3.59Å; F108-M186 HydrophobicContact CZ-CG 3.9Å; F108-M186 HydrophobicContact CZ-SD 4.12Å; V182-M186 WeakPolarHBondContact O-CB 3.39Å; V182-M186 PolarHBondContact O-N 3.45Å; L183-M186 HydrophobicContact CD2-CE 4.07Å; L183-M186 WeakPolarHBondContact O-CB 3.35Å; L183-M186 PolarHBondContact O-N 3.31Å; F184-M186 VanDerWaalsContact C-N 3.26Å; F184-M186 PolarHBondContact O-N 3.47Å; M186-T189 WeakPolarHBondContact O-CB 3.32Å; M186-T189 PolarHBondContact O-N 3.26Å; M186-F190 PolarHBondContact O-N 2.88Å; M186-I215 HydrophobicContact CB-CD1 4.28Å; M186-I215 HydrophobicContact CG-CD1 3.35Å; M186-I215 HydrophobicContact CG-CG1 4.12Å; M186-I219 HydrophobicContact CG-CD1 4.47Å; M186-I219 HydrophobicContact CG-CG1 3.77Å; M186-I219 HydrophobicContact SD-CB 4.23Å; M186-I219 HydrophobicContact SD-CG1 3.44Å; M186-I219 WeakPolarHBondContact SD-CG1 3.09Å; M186-W222 HydrophobicContact CE-CB 4.05Å; M186-W222 HydrophobicContact CE-CD2 3.32Å; M186-W222 VanDerWaalsContact CE-CE2 3.44Å; M186-W222 HydrophobicContact CE-CE3 3.88Å; M186-W222 HydrophobicContact CE-CG 3.4Å; M186-W222 HydrophobicContact CE-CZ2 4.07Å; M186-W222 HydrophobicContact CE-CZ3 4.44Å; M186-W222 HydrophobicContact SD-CB 4.27Å; M186-W222 HydrophobicContact SD-CG 4.11Å
187	A	96.6	Very high	93.6	Very high	47 Å²	47	48.8 Å²	48.8	39%	0.388	24%	0.242	S	C	.	.	H	α-helix	trans	-62.7	-43.1	175.3	0	0	0	0	0	111.7	L183 F184 T189 F190 L191	L183-A187 WeakPolarHBondContact O-CB 3.39Å; L183-A187 PolarHBondContact O-N 3.18Å; F184-A187 PolarHBondContact O-N 3.48Å; A187-T189 VanDerWaalsContact C-N 3.34Å; A187-T189 PolarHBondContact O-N 3.25Å; A187-F190 WeakPolarHBondContact O-CB 3.11Å; A187-F190 PolarHBondContact O-N 2.96Å; A187-L191 WeakPolarHBondContact O-CG 3.41Å; A187-L191 PolarHBondContact O-N 3.4Å
188	L	96.6	Very high	93.1	Very high	54 Å²	54	47.1 Å²	47.1	28%	0.283	24%	0.243	S	C	.	.	H	α-helix	trans	-63	-41.8	176	-175	61.7	0	0	0	111.2	L112 F184 L185 F190 L191 V192	L112-L188 HydrophobicContact CD1-CD2 4.21Å; L112-L188 HydrophobicContact CD1-CG 3.87Å; L112-L188 HydrophobicContact CD2-CD2 3.65Å; L112-L188 HydrophobicContact CD2-CG 4.16Å; F184-L188 HydrophobicContact CE1-CD2 4.17Å; F184-L188 HydrophobicContact CZ-CD2 4.36Å; F184-L188 VanDerWaalsContact O-CB 3.32Å; F184-L188 WeakPolarHBondContact O-CB 3.36Å; F184-L188 PolarHBondContact O-N 3.42Å; L185-L188 PolarHBondContact O-N 3.34Å; L188-F190 VanDerWaalsContact C-N 3.33Å; L188-F190 PolarHBondContact O-N 2.84Å; L188-L191 PolarHBondContact O-N 3.44Å; L188-V192 HydrophobicContact CD1-CG2 4.15Å; L188-V192 HydrophobicContact CG-CG2 4.32Å; L188-V192 WeakPolarHBondContact O-CB 3.33Å; L188-V192 VanDerWaalsContact O-CG2 3.23Å; L188-V192 WeakPolarHBondContact O-CG2 3.21Å; L188-V192 PolarHBondContact O-N 3.27Å
189	T	95.5	Very high	92.3	Very high	0 Å²	0	47 Å²	47	0%	0	25%	0.246	C	C	.	.	H	α-helix	trans	-60.1	-44.4	174.7	-57.1	0	0	0	0	111	L111 L112 L185 M186 A187 V192 S193 I211 I215	L111-T189 HydrophobicContact CB-CG2 3.84Å; L112-T189 WeakPolarHBondContact CB-OG1 3.34Å; L185-T189 WeakPolarHBondContact O-CB 3.37Å; L185-T189 PolarHBondContact O-N 2.81Å; L185-T189 PolarHBondContact O-OG1 2.74Å; M186-T189 WeakPolarHBondContact O-CB 3.32Å; M186-T189 PolarHBondContact O-N 3.26Å; A187-T189 VanDerWaalsContact C-N 3.34Å; A187-T189 PolarHBondContact O-N 3.25Å; T189-V192 PolarHBondContact O-N 2.85Å; T189-S193 WeakPolarHBondContact O-CB 3.24Å; T189-S193 PolarHBondContact O-N 3.21Å; T189-S193 PolarHBondContact O-OG 3.38Å; T189-S193 VanDerWaalsContact O-OG 3.12Å; T189-I211 HydrophobicContact CG2-CG2 4.5Å; T189-I215 HydrophobicContact CG2-CB 4.45Å; T189-I215 HydrophobicContact CG2-CD1 4.08Å; T189-I215 HydrophobicContact CG2-CG1 4.08Å
190	F	95.5	Very high	91.4	Very high	58 Å²	58	52 Å²	52	25%	0.254	28%	0.281	S	S	.	.	H	α-helix	trans	-58.7	-50.6	175.7	177.1	-99.1	0	0	0	111.6	M186 A187 L188 V192 S193 M194 F212 I215 L216 I219	M186-F190 PolarHBondContact O-N 2.88Å; A187-F190 WeakPolarHBondContact O-CB 3.11Å; A187-F190 PolarHBondContact O-N 2.96Å; L188-F190 VanDerWaalsContact C-N 3.33Å; L188-F190 PolarHBondContact O-N 2.84Å; F190-V192 PolarHBondContact O-N 3.23Å; F190-S193 WeakPolarHBondContact CA-OG 3.44Å; F190-S193 PolarHBondContact O-N 2.9Å; F190-S193 PolarHBondContact O-OG 3.28Å; F190-M194 PolarHBondContact O-N 3.09Å; F190-F212 HydrophobicContact CD2-CD2 4.36Å; F190-F212 AromaticContact CD2-CE2 3.94Å; F190-F212 HydrophobicContact CD2-CE2 3.94Å; F190-F212 HydrophobicContact CE2-CD2 4.19Å; F190-F212 AromaticContact CE2-CE2 3.35Å; F190-F212 HydrophobicContact CE2-CE2 3.35Å; F190-F212 AromaticContact CE2-CZ 3.75Å; F190-F212 HydrophobicContact CE2-CZ 3.75Å; F190-F212 AromaticContact CZ-CE2 3.9Å; F190-F212 HydrophobicContact CZ-CE2 3.9Å; F190-F212 HydrophobicContact CZ-CZ 4.24Å; F190-I215 HydrophobicContact CB-CG1 4.24Å; F190-I215 HydrophobicContact CB-CG2 4.29Å; F190-I215 HydrophobicContact CD2-CG2 4.07Å; F190-L216 HydrophobicContact CE2-CD1 4.21Å; F190-I219 HydrophobicContact CB-CD1 3.84Å; F190-I219 HydrophobicContact CD2-CD1 3.95Å; F190-I219 HydrophobicContact CG-CD1 3.97Å
191	L	94.9	Very high	90.4	Very high	88 Å²	88	49.8 Å²	49.8	46%	0.461	27%	0.266	S	S	.	.	H	α-helix	trans	-60.8	-47.4	178.1	-67.1	174	0	0	0	112.2	A187 L188 S193 M194 F195	A187-L191 WeakPolarHBondContact O-CG 3.41Å; A187-L191 PolarHBondContact O-N 3.4Å; L188-L191 PolarHBondContact O-N 3.44Å; L191-S193 VanDerWaalsContact C-N 3.33Å; L191-S193 PolarHBondContact O-N 3.06Å; L191-M194 WeakPolarHBondContact O-CB 3.35Å; L191-M194 PolarHBondContact O-N 3.4Å; L191-F195 WeakPolarHBondContact O-CD2 3.34Å; L191-F195 PolarHBondContact O-N 2.97Å
192	V	93.6	Very high	89.3	Confident	22 Å²	22	56.8 Å²	56.8	13%	0.133	30%	0.297	C	S	.	.	H	α-helix	trans	-63.5	-40.5	178.8	174.2	0	0	0	0	110.7	L112 A115 N119 L188 T189 F190 M194 F195	L112-V192 HydrophobicContact CD1-CB 4.08Å; L112-V192 HydrophobicContact CD1-CG1 4.37Å; L112-V192 HydrophobicContact CD1-CG2 3.87Å; A115-V192 HydrophobicContact CB-CB 4.43Å; A115-V192 HydrophobicContact CB-CG1 3.74Å; N119-V192 WeakPolarHBondContact ND2-CG1 3.34Å; N119-V192 PolarHBondContact ND2-O 2.76Å; L188-V192 HydrophobicContact CD1-CG2 4.15Å; L188-V192 HydrophobicContact CG-CG2 4.32Å; L188-V192 WeakPolarHBondContact O-CB 3.33Å; L188-V192 VanDerWaalsContact O-CG2 3.23Å; L188-V192 WeakPolarHBondContact O-CG2 3.21Å; L188-V192 PolarHBondContact O-N 3.27Å; T189-V192 PolarHBondContact O-N 2.85Å; F190-V192 PolarHBondContact O-N 3.23Å; V192-M194 VanDerWaalsContact C-N 3.31Å; V192-M194 PolarHBondContact O-N 3.31Å; V192-F195 PolarHBondContact O-N 3.37Å
193	S	92.1	Very high	88.3	Confident	0 Å²	0	58.4 Å²	58.4	0%	0	31%	0.309	C	S	.	.	H	α-helix	trans	-65.4	-33.1	177.1	71.7	0	0	0	0	112.4	T189 F190 L191 F195 T196 F212	T189-S193 WeakPolarHBondContact O-CB 3.24Å; T189-S193 PolarHBondContact O-N 3.21Å; T189-S193 PolarHBondContact O-OG 3.38Å; T189-S193 VanDerWaalsContact O-OG 3.12Å; F190-S193 WeakPolarHBondContact CA-OG 3.44Å; F190-S193 PolarHBondContact O-N 2.9Å; F190-S193 PolarHBondContact O-OG 3.28Å; L191-S193 VanDerWaalsContact C-N 3.33Å; L191-S193 PolarHBondContact O-N 3.06Å; S193-F195 VanDerWaalsContact C-N 3.28Å; S193-F195 PolarHBondContact O-N 3.16Å; S193-T196 VanDerWaalsContact O-CB 3.3Å; S193-T196 WeakPolarHBondContact O-CB 3.45Å; S193-T196 WeakPolarHBondContact O-CG2 3.29Å; S193-T196 PolarHBondContact O-N 3.04Å; S193-T196 PolarHBondContact O-OG1 2.91Å; S193-F212 WeakPolarHBondContact OG-CD2 3.09Å
194	M	89.8	Confident	87.4	Confident	90 Å²	90	57 Å²	57	44%	0.443	30%	0.3	S	S	.	.	H	α-helix	trans	-61.4	-36.9	174.9	-168.5	-174.7	74.1	0	0	112.1	F190 L191 V192 T196 F197	F190-M194 PolarHBondContact O-N 3.09Å; L191-M194 WeakPolarHBondContact O-CB 3.35Å; L191-M194 PolarHBondContact O-N 3.4Å; V192-M194 VanDerWaalsContact C-N 3.31Å; V192-M194 PolarHBondContact O-N 3.31Å; M194-T196 PolarHBondContact O-N 2.88Å; M194-F197 WeakPolarHBondContact O-CD2 3.11Å; M194-F197 PolarHBondContact O-N 2.98Å
195	F	88.3	Confident	86.7	Confident	107 Å²	107	54 Å²	54	47%	0.469	29%	0.287	S	S	.	.	G	3₁₀ helix	trans	-66.5	-15.4	177	-70.3	-69	0	0	0	113.8	N119 L191 V192 S193 F197 C198	N119-F195 PolarHBondContact OD1-O 2.92Å; L191-F195 WeakPolarHBondContact O-CD2 3.34Å; L191-F195 PolarHBondContact O-N 2.97Å; V192-F195 PolarHBondContact O-N 3.37Å; S193-F195 VanDerWaalsContact C-N 3.28Å; S193-F195 PolarHBondContact O-N 3.16Å; F195-F197 PolarHBondContact O-N 3.5Å; F195-C198 PolarHBondContact O-N 3.21Å
196	T	85.8	Confident	86	Confident	1 Å²	1	62.6 Å²	62.6	1%	0.006	32%	0.319	C	S	.	.	G	3₁₀ helix	trans	-66.6	-24.1	178.8	68.1	0	0	0	0	111.7	L118 N119 V122 S193 M194 C198 G208	L118-T196 HydrophobicContact CB-CG2 4.22Å; N119-T196 WeakPolarHBondContact OD1-CA 3.25Å; N119-T196 WeakPolarHBondContact OD1-CG2 3.14Å; N119-T196 PolarHBondContact OD1-N 2.98Å; V122-T196 WeakPolarHBondContact CG1-O 3.4Å; S193-T196 VanDerWaalsContact O-CB 3.3Å; S193-T196 WeakPolarHBondContact O-CB 3.45Å; S193-T196 WeakPolarHBondContact O-CG2 3.29Å; S193-T196 PolarHBondContact O-N 3.04Å; S193-T196 PolarHBondContact O-OG1 2.91Å; M194-T196 PolarHBondContact O-N 2.88Å; T196-C198 VanDerWaalsContact C-N 3.29Å; T196-C198 PolarHBondContact O-N 2.77Å; T196-G208 WeakPolarHBondContact OG1-CA 3.48Å
197	F	85.6	Confident	85.3	Confident	82 Å²	82	63.3 Å²	63.3	36%	0.36	32%	0.323	S	S	.	.	G	3₁₀ helix	trans	-75.4	-16.6	178.9	-61.8	-67.1	0	0	0	113.7	M194 F195 K205 A209 F212	M194-F197 WeakPolarHBondContact O-CD2 3.11Å; M194-F197 PolarHBondContact O-N 2.98Å; F195-F197 PolarHBondContact O-N 3.5Å; F197-K205 VanDerWaalsContact O-CE 3.32Å; F197-K205 WeakPolarHBondContact O-CE 3.32Å; F197-K205 PolarHBondContact O-NZ 2.96Å; F197-A209 HydrophobicContact CE1-CB 3.91Å; F197-A209 HydrophobicContact CZ-CB 4.11Å; F197-F212 HydrophobicContact CE2-CB 4.07Å; F197-F212 HydrophobicContact CE2-CD1 4.23Å; F197-F212 HydrophobicContact CE2-CD2 4.01Å; F197-F212 AromaticContact CE2-CG 3.83Å; F197-F212 HydrophobicContact CE2-CG 3.83Å; F197-F212 HydrophobicContact CZ-CB 4.04Å; F197-F212 HydrophobicContact CZ-CD1 4.25Å; F197-F212 HydrophobicContact CZ-CG 4.08Å
198	C	80.2	Confident	84.7	Confident	99 Å²	99	61.1 Å²	61.1	67%	0.669	30%	0.304	S	S	*	.	G	3₁₀ helix	trans	-85.4	-2.8	-170.8	-60.2	0	0	0	0	115.9	F195 T196	F195-C198 PolarHBondContact O-N 3.21Å; T196-C198 VanDerWaalsContact C-N 3.29Å; T196-C198 PolarHBondContact O-N 2.77Å
199	G	75.2	Confident	84.3	Confident	17 Å²	17	59.9 Å²	59.9	18%	0.175	30%	0.302	C	S	.	.	S	Bend	trans	-98	-171.8	-177	0	0	0	0	0	115.4	K205	G199-K205 WeakPolarHBondContact O-CE 3.31Å; G199-K205 PolarHBondContact O-NZ 3.43Å
200	S	74.3	Confident	84	Confident	107 Å²	107	62.4 Å²	62.4	75%	0.748	31%	0.313	S	S	*	.	S	Bend	trans	-90.1	-33.4	-168.4	-156.7	0	0	0	0	113.1	V122	V122-S200 PolarHBondContact O-N 3.04Å; V122-S200 VanDerWaalsContact O-N 3.14Å
201	Y	74.5	Confident	83.8	Confident	66 Å²	66	59.7 Å²	59.7	26%	0.259	30%	0.302	S	S	.	.			trans	-84.7	117.4	-171.7	-66	-89.8	0	0	0	112.9	K205	Y201-K205 WeakPolarHBondContact O-CG 3.37Å
202	K	74.1	Confident	83.8	Confident	182 Å²	182	57.6 Å²	57.6	79%	0.791	29%	0.289	S	S	*	.	H	α-helix	trans	-72.9	-30.6	-173.9	-72.4	-176.2	-179.5	177.4	0	114.7	K205	K202-K205 PolarHBondContact O-N 3.47Å
203	S	75.3	Confident	83.8	Confident	35 Å²	35	59.3 Å²	59.3	25%	0.245	30%	0.299	C	S	.	.	H	α-helix	trans	-67	-48.6	-179.3	48.6	0	0	0	0	112	K205 R206 H207 D277	S203-K205 VanDerWaalsContact C-N 3.25Å; S203-K205 PolarHBondContact O-N 3.02Å; S203-R206 WeakPolarHBondContact O-CB 3.44Å; S203-R206 PolarHBondContact O-N 3.31Å; S203-R206 VanDerWaalsContact O-N 3.08Å; S203-H207 PolarHBondContact O-CD2 3.45Å; S203-D277 WeakPolarHBondContact CB-OD1 3.48Å; S203-D277 PolarHBondContact OG-OD1 2.88Å
204	W	78.6	Confident	83.9	Confident	18 Å²	18	59.3 Å²	59.3	7%	0.068	30%	0.299	C	S	.	.	H	α-helix	trans	-62.9	-27.1	175.9	-62.1	111.7	0	0	0	114	L118 L121 V122 R206 H207 G208 D277 Y278	L118-W204 HydrophobicContact CD2-CE3 3.71Å; L118-W204 HydrophobicContact CD2-CZ3 4.32Å; L121-W204 HydrophobicContact CB-CD2 4.12Å; L121-W204 HydrophobicContact CB-CG 4.23Å; L121-W204 HydrophobicContact CD1-CD2 4.23Å; L121-W204 HydrophobicContact CD1-CE3 3.93Å; L121-W204 HydrophobicContact CD1-CH2 4.04Å; L121-W204 HydrophobicContact CD1-CZ2 4.33Å; L121-W204 HydrophobicContact CD1-CZ3 3.83Å; V122-W204 HydrophobicContact CG2-CB 3.47Å; V122-W204 VanDerWaalsContact CG2-CB 3.47Å; W204-R206 VanDerWaalsContact C-N 3.28Å; W204-R206 PolarHBondContact O-N 3.02Å; W204-H207 WeakPolarHBondContact O-CB 3.28Å; W204-H207 PolarHBondContact O-N 2.94Å; W204-G208 PolarHBondContact O-N 3.46Å; W204-D277 PolarHBondContact NE1-O 3.39Å; W204-Y278 HydrophobicContact CH2-CE1 4.23Å; W204-Y278 HydrophobicContact CZ2-CD1 4.28Å; W204-Y278 AromaticContact CZ2-CE1 3.83Å; W204-Y278 HydrophobicContact CZ2-CE1 3.83Å; W204-Y278 AromaticContact CZ2-CZ 3.98Å
205	K	81.6	Confident	84.2	Confident	57 Å²	57	55 Å²	55	25%	0.248	28%	0.278	C	S	.	.	H	α-helix	trans	-63.3	-33.9	173.5	-71.4	-177	-172.2	-159.4	0	112.6	V122 F197 G199 Y201 K202 S203 H207 G208 A209	V122-K205 HydrophobicContact CG1-CG 4.3Å; F197-K205 VanDerWaalsContact O-CE 3.32Å; F197-K205 WeakPolarHBondContact O-CE 3.32Å; F197-K205 PolarHBondContact O-NZ 2.96Å; G199-K205 WeakPolarHBondContact O-CE 3.31Å; G199-K205 PolarHBondContact O-NZ 3.43Å; Y201-K205 WeakPolarHBondContact O-CG 3.37Å; K202-K205 PolarHBondContact O-N 3.47Å; S203-K205 VanDerWaalsContact C-N 3.25Å; S203-K205 PolarHBondContact O-N 3.02Å; K205-H207 VanDerWaalsContact C-N 3.33Å; K205-G208 PolarHBondContact O-N 3.48Å; K205-A209 PolarHBondContact O-N 3.36Å
206	R	82.4	Confident	84.5	Confident	180 Å²	180	53.8 Å²	53.8	68%	0.679	28%	0.276	S	S	*	.	H	α-helix	trans	-65.2	-39.4	177.2	-172	179.5	173.1	-179.7	-0.5	111.1	S203 W204 A209 H210	S203-R206 WeakPolarHBondContact O-CB 3.44Å; S203-R206 PolarHBondContact O-N 3.31Å; S203-R206 VanDerWaalsContact O-N 3.08Å; W204-R206 VanDerWaalsContact C-N 3.28Å; W204-R206 PolarHBondContact O-N 3.02Å; R206-A209 WeakPolarHBondContact O-CB 3.16Å; R206-A209 PolarHBondContact O-N 3.31Å; R206-H210 PolarHBondContact O-CD2 3.48Å; R206-H210 PolarHBondContact O-N 2.91Å
207	H	81.4	Confident	85	Confident	20 Å²	20	58.3 Å²	58.3	9%	0.093	30%	0.296	C	S	.	.	H	α-helix	trans	-63.4	-46.4	173.1	-69.1	-77.5	0	0	0	111.9	L118 S203 W204 K205 A209 H210 I211 E265 F268	L118-H207 HydrophobicContact CD1-CB 4.05Å; L118-H207 HydrophobicContact CD2-CB 3.98Å; S203-H207 PolarHBondContact O-CD2 3.45Å; W204-H207 WeakPolarHBondContact O-CB 3.28Å; W204-H207 PolarHBondContact O-N 2.94Å; K205-H207 VanDerWaalsContact C-N 3.33Å; H207-A209 PolarHBondContact O-N 3.33Å; H207-H210 PolarHBondContact O-N 2.85Å; H207-H210 VanDerWaalsContact O-N 3.17Å; H207-I211 PolarHBondContact O-N 2.91Å; H207-E265 IonicContact CE1-OE1 3.94Å; H207-E265 IonicContact CG-OE1 3.81Å; H207-E265 IonicContact ND1-OE1 2.92Å; H207-E265 PolarHBondContact ND1-OE1 3.06Å; H207-E265 IonicContact ND1-OE2 3.77Å; H207-F268 AromaticContact CE1-CD1 3.68Å; H207-F268 AromaticContact CE1-CD2 3.48Å; H207-F268 VanDerWaalsContact CE1-CD2 3.48Å; H207-F268 WeakPolarHBondContact CE1-CD2 3.17Å; H207-F268 AromaticContact CE1-CE2 3.95Å; H207-F268 AromaticContact CE1-CG 3.32Å; H207-F268 WeakPolarHBondContact CE1-CG 3.13Å; H207-F268 AromaticContact NE2-CD2 3.44Å; H207-F268 WeakPolarHBondContact NE2-CD2 3.13Å; H207-F268 AromaticContact NE2-CE2 3.52Å; H207-F268 AromaticContact NE2-CG 3.77Å; H207-F268 AromaticContact NE2-CZ 3.92Å
208	G	83.9	Confident	85.4	Confident	0 Å²	0	54.4 Å²	54.4	0%	0	28%	0.279	C	S	.	.	H	α-helix	trans	-56	-37.2	172.9	0	0	0	0	0	112.8	T196 W204 K205 I211 F212	T196-G208 WeakPolarHBondContact OG1-CA 3.48Å; W204-G208 PolarHBondContact O-N 3.46Å; K205-G208 PolarHBondContact O-N 3.48Å; G208-I211 PolarHBondContact O-N 2.94Å; G208-F212 WeakPolarHBondContact O-CB 3.33Å; G208-F212 PolarHBondContact O-N 3.3Å
209	A	88.3	Confident	86.2	Confident	29 Å²	29	52 Å²	52	24%	0.24	26%	0.259	C	S	.	.	H	α-helix	trans	-65.3	-42	177	0	0	0	0	0	113	F197 K205 R206 H207 I211 F212 V213	F197-A209 HydrophobicContact CE1-CB 3.91Å; F197-A209 HydrophobicContact CZ-CB 4.11Å; K205-A209 PolarHBondContact O-N 3.36Å; R206-A209 WeakPolarHBondContact O-CB 3.16Å; R206-A209 PolarHBondContact O-N 3.31Å; H207-A209 PolarHBondContact O-N 3.33Å; A209-I211 VanDerWaalsContact C-N 3.34Å; A209-I211 PolarHBondContact O-N 3.47Å; A209-F212 PolarHBondContact O-N 2.88Å; A209-V213 WeakPolarHBondContact O-CB 3.43Å; A209-V213 VanDerWaalsContact O-CG2 3.29Å; A209-V213 WeakPolarHBondContact O-CG2 3.29Å; A209-V213 PolarHBondContact O-N 3.2Å
210	H	89.8	Confident	87.1	Confident	52 Å²	52	53.7 Å²	53.7	24%	0.241	27%	0.271	C	S	.	.	H	α-helix	trans	-61.4	-43.4	176.2	-76.9	-72	0	0	0	111.6	R206 H207 T214	R206-H210 PolarHBondContact O-CD2 3.48Å; R206-H210 PolarHBondContact O-N 2.91Å; H207-H210 PolarHBondContact O-N 2.85Å; H207-H210 VanDerWaalsContact O-N 3.17Å; H210-T214 WeakPolarHBondContact O-CB 3.14Å; H210-T214 PolarHBondContact O-N 3.19Å; H210-T214 PolarHBondContact O-OG1 2.67Å
211	I	91.4	Very high	88.1	Confident	1 Å²	1	50.1 Å²	50.1	1%	0.005	24%	0.243	C	C	.	.	H	α-helix	trans	-63.3	-46.3	174.9	-60.1	-176.2	0	0	0	110.9	L111 H114 A115 L118 T189 H207 G208 A209 V213 T214 I215 Y261	L111-I211 HydrophobicContact CD2-CG2 4.41Å; H114-I211 HydrophobicContact CB-CD1 4.05Å; A115-I211 HydrophobicContact CB-CG2 4.49Å; L118-I211 HydrophobicContact CD1-CD1 3.5Å; L118-I211 VanDerWaalsContact CD1-CD1 3.5Å; L118-I211 HydrophobicContact CD1-CG1 4.46Å; T189-I211 HydrophobicContact CG2-CG2 4.5Å; H207-I211 PolarHBondContact O-N 2.91Å; G208-I211 PolarHBondContact O-N 2.94Å; A209-I211 VanDerWaalsContact C-N 3.34Å; A209-I211 PolarHBondContact O-N 3.47Å; I211-V213 PolarHBondContact O-N 3.15Å; I211-T214 PolarHBondContact O-N 3.38Å; I211-I215 WeakPolarHBondContact O-CG2 3.38Å; I211-I215 PolarHBondContact O-N 2.97Å; I211-Y261 HydrophobicContact CD1-CE2 4.15Å; I211-Y261 HydrophobicContact CG1-CD2 3.99Å; I211-Y261 HydrophobicContact CG1-CE2 3.85Å
212	F	93.5	Very high	89	Confident	45 Å²	45	47.1 Å²	47.1	20%	0.197	23%	0.231	C	C	.	.	H	α-helix	trans	-59.1	-45	179.3	177.5	-94.6	0	0	0	112.4	F190 S193 F197 G208 A209 I215 L216	F190-F212 HydrophobicContact CD2-CD2 4.36Å; F190-F212 AromaticContact CD2-CE2 3.94Å; F190-F212 HydrophobicContact CD2-CE2 3.94Å; F190-F212 HydrophobicContact CE2-CD2 4.19Å; F190-F212 AromaticContact CE2-CE2 3.35Å; F190-F212 HydrophobicContact CE2-CE2 3.35Å; F190-F212 AromaticContact CE2-CZ 3.75Å; F190-F212 HydrophobicContact CE2-CZ 3.75Å; F190-F212 AromaticContact CZ-CE2 3.9Å; F190-F212 HydrophobicContact CZ-CE2 3.9Å; F190-F212 HydrophobicContact CZ-CZ 4.24Å; S193-F212 WeakPolarHBondContact OG-CD2 3.09Å; F197-F212 HydrophobicContact CE2-CB 4.07Å; F197-F212 HydrophobicContact CE2-CD1 4.23Å; F197-F212 HydrophobicContact CE2-CD2 4.01Å; F197-F212 AromaticContact CE2-CG 3.83Å; F197-F212 HydrophobicContact CE2-CG 3.83Å; F197-F212 HydrophobicContact CZ-CB 4.04Å; F197-F212 HydrophobicContact CZ-CD1 4.25Å; F197-F212 HydrophobicContact CZ-CG 4.08Å; G208-F212 WeakPolarHBondContact O-CB 3.33Å; G208-F212 PolarHBondContact O-N 3.3Å; A209-F212 PolarHBondContact O-N 2.88Å; F212-I215 WeakPolarHBondContact O-CG2 3.32Å; F212-L216 WeakPolarHBondContact O-CB 3.17Å; F212-L216 PolarHBondContact O-N 3.36Å
213	V	93.8	Very high	89.9	Confident	57 Å²	57	42.5 Å²	42.5	35%	0.345	22%	0.218	S	C	.	.	H	α-helix	trans	-65.9	-43.8	177.7	172.4	0	0	0	0	110.6	A209 I211 I215 L216 F217 M260	A209-V213 WeakPolarHBondContact O-CB 3.43Å; A209-V213 VanDerWaalsContact O-CG2 3.29Å; A209-V213 WeakPolarHBondContact O-CG2 3.29Å; A209-V213 PolarHBondContact O-N 3.2Å; I211-V213 PolarHBondContact O-N 3.15Å; V213-I215 PolarHBondContact O-N 3.3Å; V213-L216 PolarHBondContact O-N 3.48Å; V213-F217 HydrophobicContact CG1-CD2 3.71Å; V213-F217 HydrophobicContact CG1-CE2 3.67Å; V213-F217 WeakPolarHBondContact O-CD2 3.13Å; V213-F217 PolarHBondContact O-N 2.9Å; V213-M260 HydrophobicContact CG1-SD 3.99Å
214	T	94.4	Very high	90.7	Very high	0 Å²	0	45.2 Å²	45.2	0%	0	23%	0.233	C	C	.	.	H	α-helix	trans	-59.2	-47.6	178.3	-56.4	0	0	0	0	111.5	H210 I211 L216 F217 S218 I256 F257 M260	H210-T214 WeakPolarHBondContact O-CB 3.14Å; H210-T214 PolarHBondContact O-N 3.19Å; H210-T214 PolarHBondContact O-OG1 2.67Å; I211-T214 PolarHBondContact O-N 3.38Å; T214-L216 VanDerWaalsContact C-N 3.34Å; T214-L216 PolarHBondContact O-N 3.5Å; T214-F217 PolarHBondContact O-N 3.28Å; T214-S218 WeakPolarHBondContact O-CB 3.13Å; T214-S218 PolarHBondContact O-N 3.5Å; T214-I256 HydrophobicContact CG2-CG2 3.91Å; T214-F257 HydrophobicContact CG2-CD1 3.81Å; T214-F257 HydrophobicContact CG2-CE1 4.27Å; T214-M260 VanDerWaalsContact OG1-CB 3.32Å; T214-M260 WeakPolarHBondContact OG1-CB 3.45Å
215	I	95.5	Very high	91.1	Very high	0 Å²	0	44.7 Å²	44.7	0%	0	23%	0.231	C	C	.	.	H	α-helix	trans	-68.2	-34.8	-179.6	-166.1	65.7	0	0	0	111.7	F108 M186 T189 F190 I211 F212 V213 S218 I219	F108-I215 HydrophobicContact CD1-CD1 3.63Å; F108-I215 HydrophobicContact CE1-CD1 3.5Å; M186-I215 HydrophobicContact CB-CD1 4.28Å; M186-I215 HydrophobicContact CG-CD1 3.35Å; M186-I215 HydrophobicContact CG-CG1 4.12Å; T189-I215 HydrophobicContact CG2-CB 4.45Å; T189-I215 HydrophobicContact CG2-CD1 4.08Å; T189-I215 HydrophobicContact CG2-CG1 4.08Å; F190-I215 HydrophobicContact CB-CG1 4.24Å; F190-I215 HydrophobicContact CB-CG2 4.29Å; F190-I215 HydrophobicContact CD2-CG2 4.07Å; I211-I215 WeakPolarHBondContact O-CG2 3.38Å; I211-I215 PolarHBondContact O-N 2.97Å; F212-I215 WeakPolarHBondContact O-CG2 3.32Å; V213-I215 PolarHBondContact O-N 3.3Å; I215-S218 PolarHBondContact O-N 2.94Å; I215-I219 HydrophobicContact CG1-CD1 4.21Å; I215-I219 VanDerWaalsContact O-CG1 3.26Å; I215-I219 WeakPolarHBondContact O-CG1 3.49Å; I215-I219 PolarHBondContact O-N 2.93Å
216	L	95.4	Very high	91.5	Very high	81 Å²	81	43.2 Å²	43.2	42%	0.424	23%	0.226	S	C	.	.	H	α-helix	trans	-62.4	-48.5	176.2	-178.9	68.7	0	0	0	111.8	F190 F212 V213 T214 S218 I219 A220	F190-L216 HydrophobicContact CE2-CD1 4.21Å; F212-L216 WeakPolarHBondContact O-CB 3.17Å; F212-L216 PolarHBondContact O-N 3.36Å; V213-L216 PolarHBondContact O-N 3.48Å; T214-L216 VanDerWaalsContact C-N 3.34Å; T214-L216 PolarHBondContact O-N 3.5Å; L216-S218 VanDerWaalsContact C-N 3.34Å; L216-I219 PolarHBondContact O-N 2.61Å; L216-A220 PolarHBondContact O-N 3.44Å
217	F	95.6	Very high	91.8	Very high	97 Å²	97	38.1 Å²	38.1	43%	0.425	21%	0.214	S	C	.	.	H	α-helix	trans	-64.5	-39	176	-82.9	-73.1	0	0	0	112	V213 T214 A220 I221 I256 M260	V213-F217 HydrophobicContact CG1-CD2 3.71Å; V213-F217 HydrophobicContact CG1-CE2 3.67Å; V213-F217 WeakPolarHBondContact O-CD2 3.13Å; V213-F217 PolarHBondContact O-N 2.9Å; T214-F217 PolarHBondContact O-N 3.28Å; F217-A220 PolarHBondContact O-N 3.2Å; F217-I221 WeakPolarHBondContact O-CG1 3.38Å; F217-I221 PolarHBondContact O-N 3.47Å; F217-I256 HydrophobicContact CB-CD1 3.95Å; F217-I256 HydrophobicContact CB-CG1 4.44Å; F217-I256 HydrophobicContact CB-CG2 4.14Å; F217-M260 HydrophobicContact CB-SD 4.39Å; F217-M260 HydrophobicContact CD2-CE 3.57Å; F217-M260 HydrophobicContact CD2-SD 3.39Å; F217-M260 WeakPolarHBondContact CD2-SD 3.36Å; F217-M260 HydrophobicContact CE2-CE 3.59Å; F217-M260 HydrophobicContact CE2-SD 3.89Å; F217-M260 HydrophobicContact CG-CE 4.09Å; F217-M260 HydrophobicContact CG-SD 4.08Å; F217-M260 HydrophobicContact CZ-CE 4.13Å
218	S	95.4	Very high	92	Very high	0 Å²	0	40 Å²	40	0%	0	22%	0.224	C	C	.	.	H	α-helix	trans	-61.2	-44.8	173.4	178.6	0	0	0	0	111.7	F108 T214 I215 L216 A220 I221 W222 N253	F108-S218 VanDerWaalsContact CZ-OG 3.27Å; F108-S218 WeakPolarHBondContact CZ-OG 3.44Å; T214-S218 WeakPolarHBondContact O-CB 3.13Å; T214-S218 PolarHBondContact O-N 3.5Å; I215-S218 PolarHBondContact O-N 2.94Å; L216-S218 VanDerWaalsContact C-N 3.34Å; S218-A220 VanDerWaalsContact C-N 3.3Å; S218-A220 PolarHBondContact O-N 2.93Å; S218-I221 PolarHBondContact O-N 2.84Å; S218-W222 WeakPolarHBondContact O-CB 3.17Å; S218-W222 PolarHBondContact O-N 2.99Å; S218-N253 WeakPolarHBondContact CB-OD1 3.17Å; S218-N253 PolarHBondContact OG-ND2 3.13Å; S218-N253 VanDerWaalsContact OG-ND2 3.07Å; S218-N253 PolarHBondContact OG-OD1 2.68Å
219	I	95.4	Very high	92	Very high	48 Å²	48	40.1 Å²	40.1	25%	0.246	23%	0.225	C	C	.	.	H	α-helix	trans	-58.1	-45.1	176.1	-72.3	164.9	0	0	0	110.4	M186 F190 I215 L216 I221 W222 V223	M186-I219 HydrophobicContact CG-CD1 4.47Å; M186-I219 HydrophobicContact CG-CG1 3.77Å; M186-I219 HydrophobicContact SD-CB 4.23Å; M186-I219 HydrophobicContact SD-CG1 3.44Å; M186-I219 WeakPolarHBondContact SD-CG1 3.09Å; F190-I219 HydrophobicContact CB-CD1 3.84Å; F190-I219 HydrophobicContact CD2-CD1 3.95Å; F190-I219 HydrophobicContact CG-CD1 3.97Å; I215-I219 HydrophobicContact CG1-CD1 4.21Å; I215-I219 VanDerWaalsContact O-CG1 3.26Å; I215-I219 WeakPolarHBondContact O-CG1 3.49Å; I215-I219 PolarHBondContact O-N 2.93Å; L216-I219 PolarHBondContact O-N 2.61Å; I219-I221 PolarHBondContact O-N 2.82Å; I219-W222 PolarHBondContact O-N 3.4Å; I219-V223 HydrophobicContact CG2-CG2 4.36Å; I219-V223 WeakPolarHBondContact O-CG2 3.32Å; I219-V223 PolarHBondContact O-N 2.91Å
220	A	95.6	Very high	91.7	Very high	52 Å²	52	42.2 Å²	42.2	43%	0.43	23%	0.231	S	C	.	.	H	α-helix	trans	-59.6	-46.1	178.1	0	0	0	0	0	111.9	L216 F217 S218 W222 V223 V224	L216-A220 PolarHBondContact O-N 3.44Å; F217-A220 PolarHBondContact O-N 3.2Å; S218-A220 VanDerWaalsContact C-N 3.3Å; S218-A220 PolarHBondContact O-N 2.93Å; A220-W222 VanDerWaalsContact C-N 3.32Å; A220-W222 PolarHBondContact O-N 3Å; A220-V223 PolarHBondContact O-N 3.38Å; A220-V224 VanDerWaalsContact O-CG2 3.3Å; A220-V224 WeakPolarHBondContact O-CG2 3.38Å; A220-V224 PolarHBondContact O-N 3.36Å
221	I	94.1	Very high	91.1	Very high	32 Å²	32	48 Å²	48	16%	0.164	25%	0.251	C	S	.	.	H	α-helix	trans	-58.9	-45.7	174.7	-72.2	175.2	0	0	0	110.8	F217 S218 I219 V223 V224 W225 A249 N253 I256	F217-I221 WeakPolarHBondContact O-CG1 3.38Å; F217-I221 PolarHBondContact O-N 3.47Å; S218-I221 PolarHBondContact O-N 2.84Å; I219-I221 PolarHBondContact O-N 2.82Å; I221-V223 PolarHBondContact O-N 3.43Å; I221-V224 PolarHBondContact O-N 3.49Å; I221-W225 PolarHBondContact O-N 2.82Å; I221-A249 HydrophobicContact CG2-CB 4.22Å; I221-N253 HydrophobicContact CD1-CB 4.36Å; I221-I256 HydrophobicContact CD1-CD1 3.15Å; I221-I256 HydrophobicContact CG1-CD1 4.31Å
222	W	94.1	Very high	90	Very high	3 Å²	3	48.4 Å²	48.4	1%	0.011	26%	0.255	C	S	.	.	H	α-helix	trans	-61.4	-43.4	-179.2	-86.6	75.2	0	0	0	113.6	F100 F104 F108 L179 V182 L183 M186 S218 I219 A220 W225 I226 N253	F100-W222 HydrophobicContact CE1-CH2 4.02Å; F100-W222 HydrophobicContact CE1-CZ2 4.25Å; F104-W222 HydrophobicContact CB-CZ2 4.03Å; F104-W222 HydrophobicContact CD1-CZ2 4Å; F104-W222 HydrophobicContact CD2-CH2 4.38Å; F104-W222 AromaticContact CD2-CZ2 3.68Å; F104-W222 HydrophobicContact CD2-CZ2 3.68Å; F104-W222 HydrophobicContact CE1-CZ2 4.4Å; F104-W222 HydrophobicContact CE2-CZ2 4.08Å; F104-W222 AromaticContact CG-CZ2 3.65Å; F104-W222 HydrophobicContact CG-CZ2 3.65Å; F104-W222 HydrophobicContact CZ-CZ2 4.42Å; F108-W222 HydrophobicContact CE2-CZ2 4.16Å; L179-W222 HydrophobicContact CB-CH2 4.16Å; L179-W222 HydrophobicContact CB-CZ3 3.9Å; L179-W222 HydrophobicContact CD1-CH2 4.06Å; L179-W222 HydrophobicContact CD1-CZ3 3.96Å; L179-W222 HydrophobicContact CD2-CH2 4.33Å; L179-W222 HydrophobicContact CG-CH2 4.41Å; L179-W222 HydrophobicContact CG-CZ3 4.44Å; V182-W222 HydrophobicContact CB-CH2 4.08Å; V182-W222 HydrophobicContact CG1-CH2 3.59Å; V182-W222 HydrophobicContact CG1-CZ2 3.81Å; V182-W222 HydrophobicContact CG1-CZ3 4.46Å; L183-W222 HydrophobicContact CD2-CD2 4.31Å; L183-W222 HydrophobicContact CD2-CE3 3.49Å; L183-W222 VanDerWaalsContact CD2-CE3 3.49Å; L183-W222 HydrophobicContact CD2-CZ3 3.92Å; L183-W222 HydrophobicContact CG-CE3 4.27Å; L183-W222 HydrophobicContact CG-CZ3 4.21Å; M186-W222 HydrophobicContact CE-CB 4.05Å; M186-W222 HydrophobicContact CE-CD2 3.32Å; M186-W222 VanDerWaalsContact CE-CE2 3.44Å; M186-W222 HydrophobicContact CE-CE3 3.88Å; M186-W222 HydrophobicContact CE-CG 3.4Å; M186-W222 HydrophobicContact CE-CZ2 4.07Å; M186-W222 HydrophobicContact CE-CZ3 4.44Å; M186-W222 HydrophobicContact SD-CB 4.27Å; M186-W222 HydrophobicContact SD-CG 4.11Å; S218-W222 WeakPolarHBondContact O-CB 3.17Å; S218-W222 PolarHBondContact O-N 2.99Å; I219-W222 PolarHBondContact O-N 3.4Å; A220-W222 VanDerWaalsContact C-N 3.32Å; A220-W222 PolarHBondContact O-N 3Å; W222-W225 AromaticContact CD1-NE1 3.99Å; W222-W225 HydrophobicContact CD2-CZ2 4.09Å; W222-W225 AromaticContact CD2-NE1 3.45Å; W222-W225 AromaticContact CE3-CE2 3.91Å; W222-W225 AromaticContact CE3-CZ2 3.54Å; W222-W225 HydrophobicContact CE3-CZ2 3.54Å; W222-W225 AromaticContact CE3-NE1 3.75Å; W222-W225 AromaticContact CG-NE1 3.52Å; W222-W225 HydrophobicContact CH2-CZ2 4.16Å; W222-W225 AromaticContact CZ3-CZ2 3.6Å; W222-W225 HydrophobicContact CZ3-CZ2 3.6Å; W222-I226 HydrophobicContact CE3-CD1 3.89Å; W222-I226 HydrophobicContact CZ3-CD1 4.5Å; W222-I226 VanDerWaalsContact O-CB 3.29Å; W222-I226 WeakPolarHBondContact O-CB 3.34Å; W222-I226 VanDerWaalsContact O-CG1 3.24Å; W222-I226 WeakPolarHBondContact O-CG1 3.28Å; W222-I226 PolarHBondContact O-N 3.08Å; W222-N253 PolarHBondContact NE1-ND2 3.35Å
223	V	93.1	Very high	88.7	Confident	86 Å²	86	47.3 Å²	47.3	52%	0.521	25%	0.252	S	S	.	.	H	α-helix	trans	-62.1	-45.5	174.2	172.9	0	0	0	0	110.8	I219 A220 I221 T227	I219-V223 HydrophobicContact CG2-CG2 4.36Å; I219-V223 WeakPolarHBondContact O-CG2 3.32Å; I219-V223 PolarHBondContact O-N 2.91Å; A220-V223 PolarHBondContact O-N 3.38Å; I221-V223 PolarHBondContact O-N 3.43Å; V223-T227 HydrophobicContact CG1-CG2 4.45Å; V223-T227 WeakPolarHBondContact O-CB 3.4Å; V223-T227 WeakPolarHBondContact O-CG2 3.46Å; V223-T227 PolarHBondContact O-N 3.38Å; V223-T227 PolarHBondContact O-OG1 3.48Å
224	V	90.9	Very high	87.2	Confident	92 Å²	92	54.1 Å²	54.1	56%	0.558	27%	0.271	S	S	*	.	H	α-helix	trans	-63.2	-49	-179.2	171.7	0	0	0	0	111.4	A220 I221 T227 M228	A220-V224 VanDerWaalsContact O-CG2 3.3Å; A220-V224 WeakPolarHBondContact O-CG2 3.38Å; A220-V224 PolarHBondContact O-N 3.36Å; I221-V224 PolarHBondContact O-N 3.49Å; V224-T227 PolarHBondContact O-N 3.07Å; V224-T227 PolarHBondContact O-OG1 3.08Å; V224-M228 WeakPolarHBondContact O-CB 3.38Å; V224-M228 PolarHBondContact O-N 3.45Å
225	W	88.3	Confident	85.7	Confident	7 Å²	7	60 Å²	60	3%	0.027	30%	0.301	C	S	.	.	H	α-helix	trans	-73.7	-36.2	-176.5	82	-106.3	0	0	0	112.5	F100 F175 V176 L179 I221 W222 T227 M228 L229 V245 L246 A249	F100-W225 HydrophobicContact CE1-CH2 4.15Å; F100-W225 AromaticContact CE1-CZ2 3.89Å; F100-W225 HydrophobicContact CE1-CZ2 3.89Å; F100-W225 HydrophobicContact CZ-CH2 4.15Å; F100-W225 AromaticContact CZ-CZ2 3.87Å; F100-W225 HydrophobicContact CZ-CZ2 3.87Å; F175-W225 HydrophobicContact CD1-CH2 4.13Å; F175-W225 HydrophobicContact CD1-CZ3 4.14Å; F175-W225 AromaticContact CE1-CH2 3.63Å; F175-W225 HydrophobicContact CE1-CH2 3.63Å; F175-W225 AromaticContact CE1-CZ3 3.77Å; F175-W225 HydrophobicContact CE1-CZ3 3.77Å; V176-W225 HydrophobicContact CG2-CZ3 4.46Å; L179-W225 HydrophobicContact CD1-CH2 3.55Å; L179-W225 HydrophobicContact CD1-CZ2 3.91Å; I221-W225 PolarHBondContact O-N 2.82Å; W222-W225 AromaticContact CD1-NE1 3.99Å; W222-W225 HydrophobicContact CD2-CZ2 4.09Å; W222-W225 AromaticContact CD2-NE1 3.45Å; W222-W225 AromaticContact CE3-CE2 3.91Å; W222-W225 AromaticContact CE3-CZ2 3.54Å; W222-W225 HydrophobicContact CE3-CZ2 3.54Å; W222-W225 AromaticContact CE3-NE1 3.75Å; W222-W225 AromaticContact CG-NE1 3.52Å; W222-W225 HydrophobicContact CH2-CZ2 4.16Å; W222-W225 AromaticContact CZ3-CZ2 3.6Å; W222-W225 HydrophobicContact CZ3-CZ2 3.6Å; W225-T227 PolarHBondContact O-N 2.89Å; W225-M228 PolarHBondContact O-N 3.32Å; W225-L229 HydrophobicContact CE3-CB 4.23Å; W225-L229 HydrophobicContact CE3-CD2 4.3Å; W225-L229 HydrophobicContact CZ3-CB 4.42Å; W225-L229 HydrophobicContact CZ3-CD2 3.7Å; W225-L229 VanDerWaalsContact O-CB 3.28Å; W225-L229 WeakPolarHBondContact O-CB 3.47Å; W225-L229 PolarHBondContact O-N 3.43Å; W225-V245 HydrophobicContact CB-CG1 4.15Å; W225-L246 HydrophobicContact CD2-CD2 4.3Å; W225-L246 HydrophobicContact CE3-CD2 3.49Å; W225-L246 VanDerWaalsContact CE3-CD2 3.49Å; W225-L246 HydrophobicContact CH2-CD2 4.23Å; W225-L246 HydrophobicContact CZ3-CD2 3.46Å; W225-L246 VanDerWaalsContact CZ3-CD2 3.46Å; W225-A249 HydrophobicContact CB-CB 3.77Å; W225-A249 HydrophobicContact CG-CB 3.79Å
226	I	89.9	Confident	84	Confident	26 Å²	26	65.1 Å²	65.1	13%	0.133	33%	0.328	C	S	.	.	H	α-helix	trans	-62.8	-44.4	175.1	-72.2	173.5	0	0	0	110.4	V176 L183 W222 M228 L229 I230	V176-I226 HydrophobicContact CG1-CD1 4.35Å; V176-I226 HydrophobicContact CG1-CG2 4.15Å; V176-I226 HydrophobicContact CG2-CG1 4.41Å; V176-I226 HydrophobicContact CG2-CG2 4.34Å; L183-I226 HydrophobicContact CD1-CD1 4.13Å; L183-I226 HydrophobicContact CD2-CD1 4.06Å; W222-I226 HydrophobicContact CE3-CD1 3.89Å; W222-I226 HydrophobicContact CZ3-CD1 4.5Å; W222-I226 VanDerWaalsContact O-CB 3.29Å; W222-I226 WeakPolarHBondContact O-CB 3.34Å; W222-I226 VanDerWaalsContact O-CG1 3.24Å; W222-I226 WeakPolarHBondContact O-CG1 3.28Å; W222-I226 PolarHBondContact O-N 3.08Å; I226-M228 VanDerWaalsContact C-N 3.33Å; I226-M228 PolarHBondContact O-N 2.82Å; I226-L229 PolarHBondContact O-N 3.14Å; I226-I230 HydrophobicContact CG2-CD1 3.67Å; I226-I230 HydrophobicContact CG2-CG1 4.4Å; I226-I230 WeakPolarHBondContact O-CB 3.48Å; I226-I230 WeakPolarHBondContact O-CG1 3.49Å; I226-I230 PolarHBondContact O-N 3.49Å
227	T	88.4	Confident	82.2	Confident	72 Å²	72	67.8 Å²	67.8	44%	0.442	34%	0.343	S	S	.	.	H	α-helix	trans	-64.9	-39.7	178.3	52.8	0	0	0	0	111.4	V223 V224 W225 R231 G232	V223-T227 HydrophobicContact CG1-CG2 4.45Å; V223-T227 WeakPolarHBondContact O-CB 3.4Å; V223-T227 WeakPolarHBondContact O-CG2 3.46Å; V223-T227 PolarHBondContact O-N 3.38Å; V223-T227 PolarHBondContact O-OG1 3.48Å; V224-T227 PolarHBondContact O-N 3.07Å; V224-T227 PolarHBondContact O-OG1 3.08Å; W225-T227 PolarHBondContact O-N 2.89Å; T227-R231 WeakPolarHBondContact O-CB 3.29Å; T227-R231 PolarHBondContact O-N 3.49Å; T227-G232 PolarHBondContact O-N 3.49Å
228	M	85.3	Confident	80.5	Confident	60 Å²	60	69 Å²	69	30%	0.296	35%	0.348	S	S	.	.	I	π-helix	trans	-65.8	-40.7	174.8	-167.9	168.6	-176.2	0	0	112.3	V224 W225 I226 G232 W241 V245	V224-M228 WeakPolarHBondContact O-CB 3.38Å; V224-M228 PolarHBondContact O-N 3.45Å; W225-M228 PolarHBondContact O-N 3.32Å; I226-M228 VanDerWaalsContact C-N 3.33Å; I226-M228 PolarHBondContact O-N 2.82Å; M228-G232 WeakPolarHBondContact O-CA 3.47Å; M228-G232 PolarHBondContact O-N 3.33Å; M228-W241 HydrophobicContact CE-CE3 4.45Å; M228-V245 HydrophobicContact CB-CG1 4.12Å; M228-V245 HydrophobicContact CE-CG2 3.34Å; M228-V245 HydrophobicContact CG-CG1 4.03Å; M228-V245 HydrophobicContact CG-CG2 3.92Å; M228-V245 HydrophobicContact SD-CB 4.3Å; M228-V245 HydrophobicContact SD-CG1 3.86Å; M228-V245 HydrophobicContact SD-CG2 3.39Å; M228-V245 WeakPolarHBondContact SD-CG2 3.41Å
229	L	83.1	Confident	78.8	Confident	3 Å²	3	73.8 Å²	73.8	2%	0.016	38%	0.379	C	S	.	.	I	π-helix	trans	-68.6	-39.4	179.8	-168.3	76.7	0	0	0	112.5	N172 F175 V176 W225 I226 D242 L246	N172-L229 HydrophobicContact CB-CD2 4.01Å; N172-L229 HydrophobicContact CB-CG 3.94Å; N172-L229 PolarHBondContact ND2-O 2.97Å; F175-L229 HydrophobicContact CD1-CD2 3.87Å; F175-L229 HydrophobicContact CE1-CD2 4.49Å; V176-L229 HydrophobicContact CG2-CD2 4.08Å; W225-L229 HydrophobicContact CE3-CB 4.23Å; W225-L229 HydrophobicContact CE3-CD2 4.3Å; W225-L229 HydrophobicContact CZ3-CB 4.42Å; W225-L229 HydrophobicContact CZ3-CD2 3.7Å; W225-L229 VanDerWaalsContact O-CB 3.28Å; W225-L229 WeakPolarHBondContact O-CB 3.47Å; W225-L229 PolarHBondContact O-N 3.43Å; I226-L229 PolarHBondContact O-N 3.14Å; L229-D242 HydrophobicContact CD1-CB 4.04Å; L229-D242 WeakPolarHBondContact CD1-OD1 3.37Å; L229-L246 HydrophobicContact CD1-CD1 4.36Å; L229-L246 HydrophobicContact CD1-CG 4.37Å
230	I	82.5	Confident	77.1	Confident	73 Å²	73	75.9 Å²	75.9	37%	0.374	40%	0.398	S	S	.	.	I	π-helix	trans	-83.6	-39.8	-177.7	-63.5	174.5	0	0	0	112	V176 I226	V176-I230 HydrophobicContact CG1-CD1 4.39Å; V176-I230 HydrophobicContact CG2-CD1 4.22Å; V176-I230 HydrophobicContact CG2-CG1 4.35Å; I226-I230 HydrophobicContact CG2-CD1 3.67Å; I226-I230 HydrophobicContact CG2-CG1 4.4Å; I226-I230 WeakPolarHBondContact O-CB 3.48Å; I226-I230 WeakPolarHBondContact O-CG1 3.49Å; I226-I230 PolarHBondContact O-N 3.49Å
231	R	78.1	Confident	75.3	Confident	172 Å²	172	78.4 Å²	78.4	65%	0.649	40%	0.397	S	S	*	.	I	π-helix	trans	-113	-33.5	-172.5	-62.8	-176.6	178.6	-175.7	0.1	113.8	T227 N233 R234 I235	T227-R231 WeakPolarHBondContact O-CB 3.29Å; T227-R231 PolarHBondContact O-N 3.49Å; R231-N233 PolarHBondContact O-N 3.32Å; R231-R234 PolarHBondContact O-N 2.91Å; R231-I235 HydrophobicContact CB-CD1 4.17Å; R231-I235 WeakPolarHBondContact O-CG1 3.48Å; R231-I235 PolarHBondContact O-N 2.62Å
232	G	67.3	Low	74.1	Confident	10 Å²	10	77.9 Å²	77.9	10%	0.103	39%	0.394	C	S	.	.	I	π-helix	trans	-57.4	-48	-171.3	0	0	0	0	0	112.8	T227 M228 R234 I235 L236	T227-G232 PolarHBondContact O-N 3.49Å; M228-G232 WeakPolarHBondContact O-CA 3.47Å; M228-G232 PolarHBondContact O-N 3.33Å; G232-R234 VanDerWaalsContact C-N 3.3Å; G232-R234 PolarHBondContact O-N 3.15Å; G232-I235 PolarHBondContact O-N 3.44Å; G232-L236 VanDerWaalsContact O-CB 3.32Å; G232-L236 WeakPolarHBondContact O-CB 3.21Å; G232-L236 WeakPolarHBondContact O-CG 3.32Å; G232-L236 PolarHBondContact O-N 2.8Å
233	N	65.9	Low	73	Confident	23 Å²	23	80.3 Å²	80.3	12%	0.123	41%	0.407	C	S	.	.	H	α-helix	trans	-64.7	-32.4	-179.7	-77	6.3	0	0	0	113.8	R231 N237 K238 D242	R231-N233 PolarHBondContact O-N 3.32Å; N233-N237 PolarHBondContact O-N 3.05Å; N233-N237 VanDerWaalsContact O-N 3.14Å; N233-K238 PolarHBondContact OD1-O 3.18Å; N233-D242 PolarHBondContact ND2-OD1 2.96Å; N233-D242 PolarHBondContact ND2-OD2 3.21Å; N233-D242 VanDerWaalsContact ND2-OD2 3.15Å
234	R	63.8	Low	72.3	Confident	200 Å²	200	76.6 Å²	76.6	76%	0.755	39%	0.385	S	S	*	.	H	α-helix	trans	-72.3	-32.2	178.1	-160.1	-179.5	78.8	135.9	4	112.2	R231 G232	R231-R234 PolarHBondContact O-N 2.91Å; G232-R234 VanDerWaalsContact C-N 3.3Å; G232-R234 PolarHBondContact O-N 3.15Å
235	I	61.6	Low	71.9	Confident	123 Å²	123	72.6 Å²	72.6	63%	0.631	36%	0.361	S	S	*	.	H	α-helix	trans	-85.6	-37.4	-178.2	-63.1	167.8	0	0	0	110.7	R231 G232	R231-I235 HydrophobicContact CB-CD1 4.17Å; R231-I235 WeakPolarHBondContact O-CG1 3.48Å; R231-I235 PolarHBondContact O-N 2.62Å; G232-I235 PolarHBondContact O-N 3.44Å
236	L	60.3	Low	71.8	Confident	107 Å²	107	72.7 Å²	72.7	56%	0.56	36%	0.362	S	S	*	.	H	α-helix	trans	-89.4	-5.4	-176.1	-66	164.4	0	0	0	113.5	G232 K238	G232-L236 VanDerWaalsContact O-CB 3.32Å; G232-L236 WeakPolarHBondContact O-CB 3.21Å; G232-L236 WeakPolarHBondContact O-CG 3.32Å; G232-L236 PolarHBondContact O-N 2.8Å; L236-K238 PolarHBondContact O-N 2.81Å; L236-K238 VanDerWaalsContact O-N 3.08Å
237	N	58.6	Low	71.6	Confident	138 Å²	138	71.4 Å²	71.4	74%	0.738	36%	0.355	S	S	*	.	T	Hydrogen-bonded Turn	trans	50	30.3	-178.4	-77.5	-30.5	0	0	0	114.3	N233	N233-N237 PolarHBondContact O-N 3.05Å; N233-N237 VanDerWaalsContact O-N 3.14Å
238	K	59.4	Low	71.6	Confident	121 Å²	121	71.5 Å²	71.5	53%	0.526	35%	0.352	S	S	.	.			trans	-126	86.3	178.7	-69.4	-173.2	-179.5	178.8	0	110.5	N233 L236 S240 W241	N233-K238 PolarHBondContact OD1-O 3.18Å; L236-K238 PolarHBondContact O-N 2.81Å; L236-K238 VanDerWaalsContact O-N 3.08Å; K238-S240 PolarHBondContact O-N 2.9Å; K238-S240 VanDerWaalsContact O-N 3.08Å; K238-W241 VanDerWaalsContact CB-CD1 3.48Å; K238-W241 PolarHBondContact O-N 3.38Å
239	P	58.5	Low	71.9	Confident	101 Å²	101	69 Å²	69	66%	0.656	34%	0.341	S	S	*	.	G	3₁₀ helix	trans	-67.5	-5.2	-176.9	25.2	-32.5	0	0	0	114.8	W241	P239-W241 VanDerWaalsContact C-N 3.34Å
240	S	60.3	Low	72.3	Confident	93 Å²	93	68.9 Å²	68.9	65%	0.65	34%	0.34	S	S	*	.	G	3₁₀ helix	trans	-84.9	2.4	179.2	64.2	0	0	0	0	114.8	K238	K238-S240 PolarHBondContact O-N 2.9Å; K238-S240 VanDerWaalsContact O-N 3.08Å
241	W	58.7	Low	72.8	Confident	105 Å²	105	65.5 Å²	65.5	40%	0.398	32%	0.323	S	S	.	.	G	3₁₀ helix	trans	-90.5	-5.2	-174.1	-80.1	74.5	0	0	0	115.1	M228 K238 P239 P244 V245	M228-W241 HydrophobicContact CE-CE3 4.45Å; K238-W241 VanDerWaalsContact CB-CD1 3.48Å; K238-W241 PolarHBondContact O-N 3.38Å; P239-W241 VanDerWaalsContact C-N 3.34Å; W241-P244 HydrophobicContact CE3-CB 4.44Å; W241-P244 WeakPolarHBondContact O-CD 3.31Å; W241-V245 HydrophobicContact CB-CG2 4.46Å; W241-V245 WeakPolarHBondContact O-CB 3.42Å; W241-V245 WeakPolarHBondContact O-CG2 3.49Å; W241-V245 PolarHBondContact O-N 3.06Å
242	D	68.9	Low	73.6	Confident	21 Å²	21	59.5 Å²	59.5	11%	0.112	31%	0.307	C	S	.	.	H	α-helix	trans	-61.2	-50.3	-176	-73.3	-23.8	0	0	0	113.1	N172 L229 N233 V245 L246	N172-D242 PolarHBondContact ND2-OD1 3.27Å; N172-D242 PolarHBondContact ND2-OD2 3.19Å; L229-D242 HydrophobicContact CD1-CB 4.04Å; L229-D242 WeakPolarHBondContact CD1-OD1 3.37Å; N233-D242 PolarHBondContact ND2-OD1 2.96Å; N233-D242 PolarHBondContact ND2-OD2 3.21Å; N233-D242 VanDerWaalsContact ND2-OD2 3.15Å; D242-V245 PolarHBondContact O-N 2.78Å; D242-L246 WeakPolarHBondContact O-CG 3.41Å; D242-L246 PolarHBondContact O-N 3.47Å
243	D	71.4	Confident	75	Confident	53 Å²	53	59.1 Å²	59.1	28%	0.283	30%	0.303	S	S	.	.	H	α-helix	trans	-63.1	-46.3	179.5	-75.3	-15	0	0	0	112.7	R96 V245 L246 A247	R96-D243 IonicContact CZ-OD1 3.94Å; R96-D243 IonicContact CZ-OD2 3.84Å; R96-D243 IonicContact NH1-OD1 2.81Å; R96-D243 PolarHBondContact NH1-OD1 2.93Å; R96-D243 IonicContact NH1-OD2 2.9Å; R96-D243 PolarHBondContact NH1-OD2 3.42Å; R96-D243 IonicContact NH2-OD2 3.88Å; D243-V245 PolarHBondContact O-N 2.83Å; D243-L246 PolarHBondContact O-N 2.97Å; D243-A247 WeakPolarHBondContact O-CB 3.26Å; D243-A247 PolarHBondContact O-N 3.26Å
244	P	77.8	Confident	76.4	Confident	8 Å²	8	58 Å²	58	5%	0.052	30%	0.297	C	S	.	.	H	α-helix	trans	-56.6	-43.7	171.6	-23.8	26.6	0	0	0	114	W26 W241 A247 I248	W26-P244 HydrophobicContact CD2-CB 4.21Å; W26-P244 HydrophobicContact CD2-CG 4.3Å; W26-P244 HydrophobicContact CE3-CB 3.84Å; W26-P244 HydrophobicContact CE3-CG 4.22Å; W26-P244 HydrophobicContact CH2-CB 4.05Å; W26-P244 HydrophobicContact CH2-CG 3.62Å; W26-P244 HydrophobicContact CZ2-CB 4.38Å; W26-P244 HydrophobicContact CZ2-CG 3.69Å; W26-P244 HydrophobicContact CZ3-CB 3.76Å; W26-P244 HydrophobicContact CZ3-CG 3.89Å; W241-P244 HydrophobicContact CE3-CB 4.44Å; W241-P244 WeakPolarHBondContact O-CD 3.31Å; P244-A247 PolarHBondContact O-N 2.9Å; P244-I248 WeakPolarHBondContact O-CB 3.46Å; P244-I248 WeakPolarHBondContact O-CD1 3.4Å; P244-I248 WeakPolarHBondContact O-CG1 3.44Å; P244-I248 PolarHBondContact O-N 3.46Å
245	V	82.3	Confident	77.9	Confident	8 Å²	8	51.4 Å²	51.4	5%	0.048	27%	0.272	C	S	.	.	H	α-helix	trans	-65.1	-44	-177.5	170.1	0	0	0	0	111	W225 M228 W241 D242 D243 I248 A249	W225-V245 HydrophobicContact CB-CG1 4.15Å; M228-V245 HydrophobicContact CB-CG1 4.12Å; M228-V245 HydrophobicContact CE-CG2 3.34Å; M228-V245 HydrophobicContact CG-CG1 4.03Å; M228-V245 HydrophobicContact CG-CG2 3.92Å; M228-V245 HydrophobicContact SD-CB 4.3Å; M228-V245 HydrophobicContact SD-CG1 3.86Å; M228-V245 HydrophobicContact SD-CG2 3.39Å; M228-V245 WeakPolarHBondContact SD-CG2 3.41Å; W241-V245 HydrophobicContact CB-CG2 4.46Å; W241-V245 WeakPolarHBondContact O-CB 3.42Å; W241-V245 WeakPolarHBondContact O-CG2 3.49Å; W241-V245 PolarHBondContact O-N 3.06Å; D242-V245 PolarHBondContact O-N 2.78Å; D243-V245 PolarHBondContact O-N 2.83Å; V245-I248 PolarHBondContact O-N 3.46Å; V245-A249 WeakPolarHBondContact O-CB 3.27Å; V245-A249 PolarHBondContact O-N 3.13Å
246	L	85.9	Confident	79.6	Confident	9 Å²	9	46.8 Å²	46.8	5%	0.047	25%	0.248	C	C	.	.	H	α-helix	trans	-66.2	-40.7	176.5	-67.3	172.6	0	0	0	111.5	F84 F100 F175 W225 L229 D242 D243 A249 L250	F84-L246 HydrophobicContact CD1-CB 4.01Å; F84-L246 HydrophobicContact CD1-CD1 4.16Å; F84-L246 HydrophobicContact CE1-CB 3.92Å; F84-L246 HydrophobicContact CE1-CD1 3.47Å; F84-L246 VanDerWaalsContact CE1-CD1 3.47Å; F84-L246 HydrophobicContact CE1-CG 4.33Å; F84-L246 HydrophobicContact CZ-CB 4.35Å; F84-L246 HydrophobicContact CZ-CD1 4.12Å; F100-L246 HydrophobicContact CE2-CD2 4.26Å; F100-L246 HydrophobicContact CZ-CD2 4.39Å; F175-L246 HydrophobicContact CE1-CD1 4.3Å; F175-L246 HydrophobicContact CE1-CD2 3.78Å; F175-L246 HydrophobicContact CZ-CD2 4.41Å; W225-L246 HydrophobicContact CD2-CD2 4.3Å; W225-L246 HydrophobicContact CE3-CD2 3.49Å; W225-L246 VanDerWaalsContact CE3-CD2 3.49Å; W225-L246 HydrophobicContact CH2-CD2 4.23Å; W225-L246 HydrophobicContact CZ3-CD2 3.46Å; W225-L246 VanDerWaalsContact CZ3-CD2 3.46Å; L229-L246 HydrophobicContact CD1-CD1 4.36Å; L229-L246 HydrophobicContact CD1-CG 4.37Å; D242-L246 WeakPolarHBondContact O-CG 3.41Å; D242-L246 PolarHBondContact O-N 3.47Å; D243-L246 PolarHBondContact O-N 2.97Å; L246-A249 PolarHBondContact O-N 3.42Å; L246-L250 WeakPolarHBondContact O-CB 3.4Å; L246-L250 VanDerWaalsContact O-CG 3.25Å; L246-L250 WeakPolarHBondContact O-CG 3.38Å; L246-L250 PolarHBondContact O-N 2.94Å
247	A	85.8	Confident	81.3	Confident	0 Å²	0	41.7 Å²	41.7	0%	0	22%	0.222	C	C	.	.	H	α-helix	trans	-63.7	-45	175.6	0	0	0	0	0	112.2	L30 F84 D243 P244 A249 L250 V251	L30-A247 HydrophobicContact CD1-CB 3.82Å; F84-A247 HydrophobicContact CB-CB 4.26Å; D243-A247 WeakPolarHBondContact O-CB 3.26Å; D243-A247 PolarHBondContact O-N 3.26Å; P244-A247 PolarHBondContact O-N 2.9Å; A247-A249 VanDerWaalsContact C-N 3.32Å; A247-A249 PolarHBondContact O-N 2.94Å; A247-L250 PolarHBondContact O-N 3.21Å; A247-V251 WeakPolarHBondContact O-CG2 3.43Å; A247-V251 PolarHBondContact O-N 3.15Å
248	I	88.3	Confident	83	Confident	74 Å²	74	35.2 Å²	35.2	38%	0.379	19%	0.187	S	C	.	.	H	α-helix	trans	-59.8	-44.8	174.9	-67.5	161.2	0	0	0	110.3	L30 P244 V245 S252	L30-I248 HydrophobicContact CD1-CG1 3.69Å; L30-I248 HydrophobicContact CD2-CB 4.46Å; L30-I248 HydrophobicContact CD2-CG1 3.87Å; L30-I248 HydrophobicContact CG-CG1 4.3Å; P244-I248 WeakPolarHBondContact O-CB 3.46Å; P244-I248 WeakPolarHBondContact O-CD1 3.4Å; P244-I248 WeakPolarHBondContact O-CG1 3.44Å; P244-I248 PolarHBondContact O-N 3.46Å; V245-I248 PolarHBondContact O-N 3.46Å; I248-S252 WeakPolarHBondContact O-CB 3.46Å; I248-S252 PolarHBondContact O-N 3.43Å; I248-S252 PolarHBondContact O-OG 3.34Å
249	A	90.9	Very high	84.7	Confident	6 Å²	6	34.3 Å²	34.3	5%	0.05	19%	0.187	C	C	.	.	H	α-helix	trans	-62.2	-44.4	179.1	0	0	0	0	0	112	I221 W225 V245 L246 A247 N253	I221-A249 HydrophobicContact CG2-CB 4.22Å; W225-A249 HydrophobicContact CB-CB 3.77Å; W225-A249 HydrophobicContact CG-CB 3.79Å; V245-A249 WeakPolarHBondContact O-CB 3.27Å; V245-A249 PolarHBondContact O-N 3.13Å; L246-A249 PolarHBondContact O-N 3.42Å; A247-A249 VanDerWaalsContact C-N 3.32Å; A247-A249 PolarHBondContact O-N 2.94Å; A249-N253 VanDerWaalsContact O-CB 3.27Å; A249-N253 WeakPolarHBondContact O-CB 3.38Å; A249-N253 PolarHBondContact O-N 3.39Å
250	L	92.4	Very high	86.3	Confident	1 Å²	1	32 Å²	32	1%	0.005	17%	0.168	C	C	.	.	H	α-helix	trans	-61.1	-53	177	-75.5	166.1	0	0	0	111.8	I77 L80 T81 F84 F100 F104 L246 A247 S252 N253 G254	I77-L250 HydrophobicContact CG2-CB 4.18Å; I77-L250 HydrophobicContact CG2-CD2 3.87Å; I77-L250 WeakPolarHBondContact CG2-O 3.33Å; L80-L250 HydrophobicContact CB-CD1 4.48Å; L80-L250 HydrophobicContact CD2-CD1 4.23Å; L80-L250 HydrophobicContact CD2-CD2 4.19Å; L80-L250 HydrophobicContact CG-CD1 4.25Å; T81-L250 HydrophobicContact CG2-CB 3.45Å; T81-L250 VanDerWaalsContact CG2-CB 3.45Å; T81-L250 HydrophobicContact CG2-CD1 4.08Å; T81-L250 HydrophobicContact CG2-CG 4.4Å; F84-L250 HydrophobicContact CD2-CD1 3.45Å; F84-L250 VanDerWaalsContact CD2-CD1 3.45Å; F84-L250 HydrophobicContact CE2-CD1 3.64Å; F84-L250 HydrophobicContact CG-CD1 4.4Å; F100-L250 HydrophobicContact CD2-CD1 4.19Å; F100-L250 HydrophobicContact CD2-CD2 3.81Å; F100-L250 HydrophobicContact CD2-CG 4.21Å; F100-L250 HydrophobicContact CE2-CD1 4.1Å; F100-L250 HydrophobicContact CE2-CD2 3.62Å; F100-L250 HydrophobicContact CE2-CG 3.76Å; F100-L250 HydrophobicContact CZ-CD2 4.42Å; F104-L250 HydrophobicContact CE2-CD2 3.55Å; F104-L250 HydrophobicContact CZ-CD2 3.84Å; L246-L250 WeakPolarHBondContact O-CB 3.4Å; L246-L250 VanDerWaalsContact O-CG 3.25Å; L246-L250 WeakPolarHBondContact O-CG 3.38Å; L246-L250 PolarHBondContact O-N 2.94Å; A247-L250 PolarHBondContact O-N 3.21Å; L250-S252 PolarHBondContact O-N 3.07Å; L250-N253 PolarHBondContact O-N 2.93Å; L250-G254 PolarHBondContact O-N 3.47Å
251	V	93.8	Very high	87.8	Confident	3 Å²	3	27.6 Å²	27.6	2%	0.018	14%	0.137	C	C	.	.	H	α-helix	trans	-60.2	-48.8	179.9	172.9	0	0	0	0	110.4	L30 L33 A34 T81 A247 N253 G254 W255	L30-V251 HydrophobicContact CD2-CB 4.22Å; L30-V251 HydrophobicContact CD2-CG1 4.47Å; L30-V251 HydrophobicContact CD2-CG2 4.07Å; L33-V251 HydrophobicContact CB-CG1 3.69Å; L33-V251 HydrophobicContact CD1-CG1 4.26Å; A34-V251 HydrophobicContact CB-CG2 4.21Å; T81-V251 HydrophobicContact CG2-CG2 3.49Å; T81-V251 VanDerWaalsContact CG2-CG2 3.49Å; A247-V251 WeakPolarHBondContact O-CG2 3.43Å; A247-V251 PolarHBondContact O-N 3.15Å; V251-N253 PolarHBondContact O-N 2.9Å; V251-G254 PolarHBondContact O-N 3.39Å; V251-W255 PolarHBondContact O-N 3.16Å
252	S	94.4	Very high	89.4	Confident	46 Å²	46	22.6 Å²	22.6	32%	0.322	12%	0.118	S	C	.	.	H	α-helix	trans	-60.4	-45.2	-178.3	-57.5	0	0	0	0	111.6	I248 L250 W255 I256	I248-S252 WeakPolarHBondContact O-CB 3.46Å; I248-S252 PolarHBondContact O-N 3.43Å; I248-S252 PolarHBondContact O-OG 3.34Å; L250-S252 PolarHBondContact O-N 3.07Å; S252-W255 PolarHBondContact O-N 3.12Å; S252-I256 PolarHBondContact O-N 3.43Å; S252-I256 VanDerWaalsContact O-N 3.11Å
253	N	95.4	Very high	90.4	Very high	1 Å²	1	24.8 Å²	24.8	1%	0.005	13%	0.132	C	C	.	.	H	α-helix	trans	-70.2	-38.2	-179.7	-149	6.6	0	0	0	111.9	F104 S218 I221 W222 A249 L250 V251 W255 I256 F257	F104-N253 HydrophobicContact CE1-CB 4.24Å; F104-N253 VanDerWaalsContact CE1-ND2 3.28Å; F104-N253 WeakPolarHBondContact CE1-ND2 3.45Å; F104-N253 HydrophobicContact CZ-CB 4.4Å; S218-N253 WeakPolarHBondContact CB-OD1 3.17Å; S218-N253 PolarHBondContact OG-ND2 3.13Å; S218-N253 VanDerWaalsContact OG-ND2 3.07Å; S218-N253 PolarHBondContact OG-OD1 2.68Å; I221-N253 HydrophobicContact CD1-CB 4.36Å; W222-N253 PolarHBondContact NE1-ND2 3.35Å; A249-N253 VanDerWaalsContact O-CB 3.27Å; A249-N253 WeakPolarHBondContact O-CB 3.38Å; A249-N253 PolarHBondContact O-N 3.39Å; L250-N253 PolarHBondContact O-N 2.93Å; V251-N253 PolarHBondContact O-N 2.9Å; N253-W255 VanDerWaalsContact C-N 3.35Å; N253-W255 PolarHBondContact O-N 2.9Å; N253-I256 PolarHBondContact O-N 3.3Å; N253-F257 WeakPolarHBondContact O-CB 3.46Å; N253-F257 VanDerWaalsContact O-CG 3.31Å; N253-F257 WeakPolarHBondContact O-CG 3.47Å; N253-F257 PolarHBondContact O-N 2.99Å; N253-F257 WeakPolarHBondContact OD1-CE1 3.38Å
254	G	95.6	Very high	91.2	Very high	0 Å²	0	23.8 Å²	23.8	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-58.4	-43.8	173.3	0	0	0	0	0	112.5	L250 V251 F257 L258	L250-G254 PolarHBondContact O-N 3.47Å; V251-G254 PolarHBondContact O-N 3.39Å; G254-F257 WeakPolarHBondContact O-CB 3.31Å; G254-F257 PolarHBondContact O-N 2.91Å; G254-L258 WeakPolarHBondContact O-CG 3.46Å; G254-L258 PolarHBondContact O-N 3.2Å
255	W	96.7	Very high	91.6	Very high	62 Å²	62	23.5 Å²	23.5	24%	0.235	13%	0.127	C	C	.	.	H	α-helix	trans	-66.9	-37.7	176.3	-80.8	106.3	0	0	0	113	L33 A36 V40 F78 V251 S252 N253 F257 L258 I259	L33-W255 PolarHBondContact O-NE1 3.18Å; A36-W255 HydrophobicContact CB-CH2 4.34Å; A36-W255 HydrophobicContact CB-CZ2 3.96Å; V40-W255 HydrophobicContact CG2-CH2 4.44Å; F78-W255 AromaticContact CE1-CD1 3.85Å; F78-W255 HydrophobicContact CE1-CG 4.37Å; F78-W255 AromaticContact CE1-NE1 3.87Å; F78-W255 HydrophobicContact CZ-CD2 4.45Å; F78-W255 HydrophobicContact CZ-CG 4.29Å; V251-W255 PolarHBondContact O-N 3.16Å; S252-W255 PolarHBondContact O-N 3.12Å; N253-W255 VanDerWaalsContact C-N 3.35Å; N253-W255 PolarHBondContact O-N 2.9Å; W255-F257 VanDerWaalsContact C-N 3.34Å; W255-L258 PolarHBondContact O-N 3.43Å; W255-I259 HydrophobicContact CE3-CD1 3.92Å; W255-I259 HydrophobicContact CE3-CG1 4.25Å; W255-I259 WeakPolarHBondContact O-CB 3.26Å; W255-I259 WeakPolarHBondContact O-CG1 3.47Å; W255-I259 PolarHBondContact O-N 3.41Å
256	I	96.2	Very high	91.8	Very high	25 Å²	25	23.8 Å²	23.8	13%	0.128	13%	0.128	C	C	.	.	H	α-helix	trans	-60.9	-44.9	172.7	-78.2	155.3	0	0	0	111	T214 F217 I221 S252 N253 L258 I259 M260	T214-I256 HydrophobicContact CG2-CG2 3.91Å; F217-I256 HydrophobicContact CB-CD1 3.95Å; F217-I256 HydrophobicContact CB-CG1 4.44Å; F217-I256 HydrophobicContact CB-CG2 4.14Å; I221-I256 HydrophobicContact CD1-CD1 3.15Å; I221-I256 HydrophobicContact CG1-CD1 4.31Å; S252-I256 PolarHBondContact O-N 3.43Å; S252-I256 VanDerWaalsContact O-N 3.11Å; N253-I256 PolarHBondContact O-N 3.3Å; I256-L258 VanDerWaalsContact C-N 3.32Å; I256-L258 PolarHBondContact O-N 2.86Å; I256-I259 PolarHBondContact O-N 3.19Å; I256-M260 HydrophobicContact CG1-CE 4.44Å; I256-M260 HydrophobicContact CG1-SD 4.46Å; I256-M260 HydrophobicContact CG2-CG 4.41Å; I256-M260 HydrophobicContact CG2-SD 3.99Å; I256-M260 VanDerWaalsContact O-CB 3.3Å; I256-M260 WeakPolarHBondContact O-CB 3.41Å; I256-M260 PolarHBondContact O-N 3.04Å
257	F	95.9	Very high	91.6	Very high	0 Å²	0	26.9 Å²	26.9	0%	0	15%	0.15	C	C	.	.	I	π-helix	trans	-59.1	-41.1	176.3	-74.5	-3.6	0	0	0	112.7	F70 T74 I77 F104 C107 F108 L111 T214 N253 G254 W255 Y261 I262	F70-F257 HydrophobicContact CE1-CB 3.73Å; F70-F257 HydrophobicContact CE1-CD2 4.45Å; F70-F257 HydrophobicContact CE1-CG 4.19Å; F70-F257 HydrophobicContact CE2-CD2 4.34Å; F70-F257 HydrophobicContact CE2-CG 4.34Å; F70-F257 HydrophobicContact CZ-CB 3.51Å; F70-F257 HydrophobicContact CZ-CD1 4Å; F70-F257 AromaticContact CZ-CD2 3.77Å; F70-F257 HydrophobicContact CZ-CD2 3.77Å; F70-F257 HydrophobicContact CZ-CE2 4.49Å; F70-F257 AromaticContact CZ-CG 3.49Å; F70-F257 HydrophobicContact CZ-CG 3.49Å; F70-F257 VanDerWaalsContact CZ-CG 3.49Å; T74-F257 HydrophobicContact CG2-CB 4.34Å; I77-F257 HydrophobicContact CD1-CD2 4.15Å; I77-F257 HydrophobicContact CD1-CE2 3.86Å; F104-F257 HydrophobicContact CD1-CE2 4.25Å; F104-F257 HydrophobicContact CD1-CZ 4.43Å; F104-F257 HydrophobicContact CE1-CE2 4.13Å; F104-F257 HydrophobicContact CE1-CZ 4.37Å; C107-F257 HydrophobicContact CB-CD2 4.41Å; C107-F257 HydrophobicContact CB-CE2 3.77Å; C107-F257 HydrophobicContact CB-CZ 4.38Å; F108-F257 HydrophobicContact CE1-CE1 4.25Å; F108-F257 AromaticContact CE1-CZ 3.85Å; F108-F257 HydrophobicContact CE1-CZ 3.85Å; F108-F257 AromaticContact CZ-CZ 3.98Å; F108-F257 HydrophobicContact CZ-CZ 3.98Å; L111-F257 HydrophobicContact CD1-CE1 4.36Å; T214-F257 HydrophobicContact CG2-CD1 3.81Å; T214-F257 HydrophobicContact CG2-CE1 4.27Å; N253-F257 WeakPolarHBondContact O-CB 3.46Å; N253-F257 VanDerWaalsContact O-CG 3.31Å; N253-F257 WeakPolarHBondContact O-CG 3.47Å; N253-F257 PolarHBondContact O-N 2.99Å; N253-F257 WeakPolarHBondContact OD1-CE1 3.38Å; G254-F257 WeakPolarHBondContact O-CB 3.31Å; G254-F257 PolarHBondContact O-N 2.91Å; W255-F257 VanDerWaalsContact C-N 3.34Å; F257-Y261 WeakPolarHBondContact O-CB 3.4Å; F257-I262 PolarHBondContact O-N 3.2Å
258	L	94.6	Very high	91.2	Very high	3 Å²	3	28.8 Å²	28.8	2%	0.016	16%	0.158	C	C	.	.	I	π-helix	trans	-69.7	-54.1	176.3	-68.2	-174.3	0	0	0	112.3	V40 L44 L71 T74 F78 G254 W255 I256 I262 V263	V40-L258 HydrophobicContact CB-CD1 4.36Å; V40-L258 HydrophobicContact CG1-CD1 3.94Å; L44-L258 HydrophobicContact CD1-CD2 3.87Å; L71-L258 HydrophobicContact CD2-CD2 4.14Å; T74-L258 HydrophobicContact CG2-CD2 3.98Å; T74-L258 HydrophobicContact CG2-CG 4.15Å; F78-L258 HydrophobicContact CE2-CD1 3.59Å; F78-L258 HydrophobicContact CE2-CG 4.06Å; F78-L258 HydrophobicContact CZ-CD1 3.89Å; F78-L258 HydrophobicContact CZ-CG 4.41Å; G254-L258 WeakPolarHBondContact O-CG 3.46Å; G254-L258 PolarHBondContact O-N 3.2Å; W255-L258 PolarHBondContact O-N 3.43Å; I256-L258 VanDerWaalsContact C-N 3.32Å; I256-L258 PolarHBondContact O-N 2.86Å; L258-I262 PolarHBondContact O-N 3.18Å; L258-V263 WeakPolarHBondContact O-CG2 3.33Å; L258-V263 PolarHBondContact O-N 2.88Å
259	I	94.5	Very high	90.6	Very high	101 Å²	101	25.8 Å²	25.8	52%	0.518	14%	0.142	S	C	.	.	I	π-helix	trans	-75.1	-45.7	-169.1	-63	168.9	0	0	0	111.6	W255 I256 P264	W255-I259 HydrophobicContact CE3-CD1 3.92Å; W255-I259 HydrophobicContact CE3-CG1 4.25Å; W255-I259 WeakPolarHBondContact O-CB 3.26Å; W255-I259 WeakPolarHBondContact O-CG1 3.47Å; W255-I259 PolarHBondContact O-N 3.41Å; I256-I259 PolarHBondContact O-N 3.19Å; I259-P264 VanDerWaalsContact O-CD 3.28Å; I259-P264 WeakPolarHBondContact O-CD 3.47Å
260	M	91.8	Very high	89.8	Confident	53 Å²	53	29.3 Å²	29.3	26%	0.261	16%	0.163	S	C	.	.	I	π-helix	trans	-87.6	-25.3	-171.3	-61	-169.9	176.7	0	0	113.3	V213 T214 F217 I256	V213-M260 HydrophobicContact CG1-SD 3.99Å; T214-M260 VanDerWaalsContact OG1-CB 3.32Å; T214-M260 WeakPolarHBondContact OG1-CB 3.45Å; F217-M260 HydrophobicContact CB-SD 4.39Å; F217-M260 HydrophobicContact CD2-CE 3.57Å; F217-M260 HydrophobicContact CD2-SD 3.39Å; F217-M260 WeakPolarHBondContact CD2-SD 3.36Å; F217-M260 HydrophobicContact CE2-CE 3.59Å; F217-M260 HydrophobicContact CE2-SD 3.89Å; F217-M260 HydrophobicContact CG-CE 4.09Å; F217-M260 HydrophobicContact CG-SD 4.08Å; F217-M260 HydrophobicContact CZ-CE 4.13Å; I256-M260 HydrophobicContact CG1-CE 4.44Å; I256-M260 HydrophobicContact CG1-SD 4.46Å; I256-M260 HydrophobicContact CG2-CG 4.41Å; I256-M260 HydrophobicContact CG2-SD 3.99Å; I256-M260 VanDerWaalsContact O-CB 3.3Å; I256-M260 WeakPolarHBondContact O-CB 3.41Å; I256-M260 PolarHBondContact O-N 3.04Å
261	Y	92.7	Very high	88.8	Confident	0 Å²	0	31.1 Å²	31.1	0%	0	18%	0.179	C	C	.	.	I	π-helix	trans	-112	-62.7	-178.3	174.5	-115.6	0	0	0	112.9	F70 L111 H114 I211 F257 P264 E265	F70-Y261 HydrophobicContact CB-CE1 4.46Å; F70-Y261 AromaticContact CD1-CD1 3.87Å; F70-Y261 HydrophobicContact CD1-CD1 3.87Å; F70-Y261 AromaticContact CD1-CE1 3.79Å; F70-Y261 HydrophobicContact CD1-CE1 3.79Å; F70-Y261 HydrophobicContact CD2-CD1 4.23Å; F70-Y261 AromaticContact CD2-CE1 3.81Å; F70-Y261 HydrophobicContact CD2-CE1 3.81Å; F70-Y261 AromaticContact CE1-CD1 3.45Å; F70-Y261 HydrophobicContact CE1-CD1 3.45Å; F70-Y261 VanDerWaalsContact CE1-CD1 3.45Å; F70-Y261 AromaticContact CE1-CE1 3.86Å; F70-Y261 HydrophobicContact CE1-CE1 3.86Å; F70-Y261 AromaticContact CE2-CD1 3.88Å; F70-Y261 HydrophobicContact CE2-CD1 3.88Å; F70-Y261 AromaticContact CE2-CE1 3.9Å; F70-Y261 HydrophobicContact CE2-CE1 3.9Å; F70-Y261 HydrophobicContact CG-CD1 4.21Å; F70-Y261 AromaticContact CG-CE1 3.74Å; F70-Y261 HydrophobicContact CG-CE1 3.74Å; F70-Y261 AromaticContact CZ-CD1 3.43Å; F70-Y261 HydrophobicContact CZ-CD1 3.43Å; F70-Y261 VanDerWaalsContact CZ-CD1 3.43Å; F70-Y261 AromaticContact CZ-CE1 3.89Å; F70-Y261 HydrophobicContact CZ-CE1 3.89Å; F70-Y261 HydrophobicContact CZ-CG 4.44Å; L111-Y261 HydrophobicContact CD2-CD1 3.76Å; L111-Y261 HydrophobicContact CD2-CD2 3.8Å; L111-Y261 HydrophobicContact CD2-CE1 3.65Å; L111-Y261 HydrophobicContact CD2-CE2 3.7Å; L111-Y261 HydrophobicContact CD2-CG 3.82Å; H114-Y261 AromaticContact ND1-CE2 3.52Å; H114-Y261 AromaticContact ND1-CZ 3.67Å; H114-Y261 PolarHBondContact ND1-OH 3.47Å; I211-Y261 HydrophobicContact CD1-CE2 4.15Å; I211-Y261 HydrophobicContact CG1-CD2 3.99Å; I211-Y261 HydrophobicContact CG1-CE2 3.85Å; F257-Y261 WeakPolarHBondContact O-CB 3.4Å; Y261-P264 WeakPolarHBondContact O-CD 3.4Å; Y261-E265 HydrophobicContact CD2-CG 4.05Å; Y261-E265 HydrophobicContact CE2-CG 3.92Å; Y261-E265 WeakPolarHBondContact O-CB 3.36Å; Y261-E265 WeakPolarHBondContact O-CG 3.41Å; Y261-E265 PolarHBondContact O-N 2.87Å
262	I	92.4	Very high	87.4	Confident	0 Å²	0	36.1 Å²	36.1	0%	0	21%	0.211	C	C	.	.	I	π-helix	trans	-68	-44.4	-170.5	-69.4	-64.5	0	0	0	113.5	L44 Y67 F70 L71 F257 L258 E265 I266	L44-I262 HydrophobicContact CD1-CG2 3.94Å; Y67-I262 HydrophobicContact CD1-CD1 4.33Å; F70-I262 HydrophobicContact CD1-CD1 3.48Å; F70-I262 VanDerWaalsContact CD1-CD1 3.48Å; F70-I262 HydrophobicContact CD1-CG1 3.59Å; F70-I262 HydrophobicContact CE1-CD1 3.95Å; F70-I262 HydrophobicContact CE1-CG1 3.58Å; F70-I262 HydrophobicContact CG-CD1 4.3Å; L71-I262 HydrophobicContact CD2-CG1 4.24Å; L71-I262 HydrophobicContact CD2-CG2 4.08Å; L71-I262 HydrophobicContact CG-CD1 4.24Å; L71-I262 HydrophobicContact CG-CG1 4.5Å; F257-I262 PolarHBondContact O-N 3.2Å; L258-I262 PolarHBondContact O-N 3.18Å; I262-E265 PolarHBondContact O-N 3.22Å; I262-I266 HydrophobicContact CG2-CD1 3.41Å; I262-I266 VanDerWaalsContact CG2-CD1 3.41Å; I262-I266 HydrophobicContact CG2-CG1 4.04Å; I262-I266 WeakPolarHBondContact O-CG1 3.48Å; I262-I266 PolarHBondContact O-N 3.38Å
263	V	89.3	Confident	85.9	Confident	67 Å²	67	38.5 Å²	38.5	41%	0.406	22%	0.22	S	C	.	.	H	α-helix	trans	-59.7	-51.5	-178.3	167.4	0	0	0	0	111.6	L258 E265 I266 C267	L258-V263 WeakPolarHBondContact O-CG2 3.33Å; L258-V263 PolarHBondContact O-N 2.88Å; V263-E265 VanDerWaalsContact C-N 3.29Å; V263-E265 PolarHBondContact O-N 3.38Å; V263-I266 PolarHBondContact O-N 3.32Å; V263-C267 PolarHBondContact O-N 3.39Å; V263-C267 PolarHBondContact O-SG 3.29Å
264	P	87.9	Confident	84.3	Confident	33 Å²	33	45 Å²	45	21%	0.214	25%	0.248	C	C	.	.	H	α-helix	trans	-56.8	-40.4	175.3	-28	35.5	0	0	0	113.8	I259 Y261 F268	I259-P264 VanDerWaalsContact O-CD 3.28Å; I259-P264 WeakPolarHBondContact O-CD 3.47Å; Y261-P264 WeakPolarHBondContact O-CD 3.4Å; P264-F268 PolarHBondContact O-N 2.92Å; P264-F268 VanDerWaalsContact O-N 3.07Å
265	E	87.4	Confident	82.4	Confident	2 Å²	2	51.8 Å²	51.8	1%	0.009	28%	0.284	C	S	.	.	H	α-helix	trans	-70.5	-40.2	-178	-70	-64.4	140	0	0	112.4	Y67 H114 H207 Y261 I262 V263 F268 L269	Y67-E265 HydrophobicContact CD1-CB 4.47Å; Y67-E265 HydrophobicContact CE1-CB 3.75Å; Y67-E265 HydrophobicContact CE1-CG 3.98Å; Y67-E265 PolarHBondContact OH-OE2 3.09Å; H114-E265 IonicContact CE1-OE2 3.42Å; H114-E265 PolarHBondContact CE1-OE2 3.45Å; H207-E265 IonicContact CE1-OE1 3.94Å; H207-E265 IonicContact CG-OE1 3.81Å; H207-E265 IonicContact ND1-OE1 2.92Å; H207-E265 PolarHBondContact ND1-OE1 3.06Å; H207-E265 IonicContact ND1-OE2 3.77Å; Y261-E265 HydrophobicContact CD2-CG 4.05Å; Y261-E265 HydrophobicContact CE2-CG 3.92Å; Y261-E265 WeakPolarHBondContact O-CB 3.36Å; Y261-E265 WeakPolarHBondContact O-CG 3.41Å; Y261-E265 PolarHBondContact O-N 2.87Å; I262-E265 PolarHBondContact O-N 3.22Å; V263-E265 VanDerWaalsContact C-N 3.29Å; V263-E265 PolarHBondContact O-N 3.38Å; E265-F268 WeakPolarHBondContact O-CB 3.28Å; E265-F268 PolarHBondContact O-N 3.29Å; E265-L269 PolarHBondContact O-N 3.45Å
266	I	85.2	Confident	80.7	Confident	13 Å²	13	57.2 Å²	57.2	7%	0.067	31%	0.312	C	S	.	.	H	α-helix	trans	-67.8	-42	174.7	-69.2	175.4	0	0	0	110.9	L44 F51 I262 V263 F268 L269 T270	L44-I266 HydrophobicContact CB-CD1 4.15Å; L44-I266 HydrophobicContact CD2-CD1 3.72Å; L44-I266 HydrophobicContact CG-CD1 4.42Å; F51-I266 HydrophobicContact CD2-CG2 4.47Å; F51-I266 HydrophobicContact CE2-CG2 3.84Å; I262-I266 HydrophobicContact CG2-CD1 3.41Å; I262-I266 VanDerWaalsContact CG2-CD1 3.41Å; I262-I266 HydrophobicContact CG2-CG1 4.04Å; I262-I266 WeakPolarHBondContact O-CG1 3.48Å; I262-I266 PolarHBondContact O-N 3.38Å; V263-I266 PolarHBondContact O-N 3.32Å; I266-F268 PolarHBondContact O-N 3.27Å; I266-L269 WeakPolarHBondContact O-CB 3.3Å; I266-L269 PolarHBondContact O-N 3.11Å; I266-L269 VanDerWaalsContact O-N 3.1Å; I266-T270 PolarHBondContact O-N 3.32Å; I266-T270 VanDerWaalsContact O-N 3.11Å
267	C	83	Confident	79	Confident	75 Å²	75	57.3 Å²	57.3	51%	0.507	31%	0.313	S	S	.	.	H	α-helix	trans	-57.1	-37.6	173.9	-70.7	0	0	0	0	111.5	V263 T270 A271	V263-C267 PolarHBondContact O-N 3.39Å; V263-C267 PolarHBondContact O-SG 3.29Å; C267-T270 PolarHBondContact O-N 3.34Å; C267-T270 PolarHBondContact O-OG1 3.05Å; C267-A271 PolarHBondContact O-N 3.47Å
268	F	77.3	Confident	77.3	Confident	39 Å²	39	59.7 Å²	59.7	17%	0.171	32%	0.322	C	S	.	.	H	α-helix	trans	-69.4	-39	174.9	174.5	-101.2	0	0	0	113.6	H207 P264 E265 I266 T270 A271	H207-F268 AromaticContact CE1-CD1 3.68Å; H207-F268 AromaticContact CE1-CD2 3.48Å; H207-F268 VanDerWaalsContact CE1-CD2 3.48Å; H207-F268 WeakPolarHBondContact CE1-CD2 3.17Å; H207-F268 AromaticContact CE1-CE2 3.95Å; H207-F268 AromaticContact CE1-CG 3.32Å; H207-F268 WeakPolarHBondContact CE1-CG 3.13Å; H207-F268 AromaticContact NE2-CD2 3.44Å; H207-F268 WeakPolarHBondContact NE2-CD2 3.13Å; H207-F268 AromaticContact NE2-CE2 3.52Å; H207-F268 AromaticContact NE2-CG 3.77Å; H207-F268 AromaticContact NE2-CZ 3.92Å; P264-F268 PolarHBondContact O-N 2.92Å; P264-F268 VanDerWaalsContact O-N 3.07Å; E265-F268 WeakPolarHBondContact O-CB 3.28Å; E265-F268 PolarHBondContact O-N 3.29Å; I266-F268 PolarHBondContact O-N 3.27Å; F268-T270 PolarHBondContact O-N 2.99Å; F268-A271 WeakPolarHBondContact O-CB 3.27Å; F268-A271 PolarHBondContact O-N 3.35Å
269	L	75.2	Confident	75.6	Confident	11 Å²	11	61.4 Å²	61.4	6%	0.058	33%	0.333	C	S	.	.	H	α-helix	trans	-57.4	-34.8	173.2	-73.7	175.7	0	0	0	111.7	K60 Y67 E265 I266	K60-L269 HydrophobicContact CB-CD2 3.96Å; K60-L269 HydrophobicContact CG-CD2 4.35Å; Y67-L269 HydrophobicContact CD2-CD1 3.77Å; Y67-L269 HydrophobicContact CE2-CD1 3.65Å; Y67-L269 HydrophobicContact CE2-CD2 4.16Å; Y67-L269 HydrophobicContact CE2-CG 4.07Å; E265-L269 PolarHBondContact O-N 3.45Å; I266-L269 WeakPolarHBondContact O-CB 3.3Å; I266-L269 PolarHBondContact O-N 3.11Å; I266-L269 VanDerWaalsContact O-N 3.1Å
270	T	73.4	Confident	73.7	Confident	80 Å²	80	61.6 Å²	61.6	49%	0.491	34%	0.341	S	S	.	.	H	α-helix	trans	-79.2	-16.3	176.1	63.2	0	0	0	0	114.8	F51 I266 C267 F268	F51-T270 HydrophobicContact CD1-CG2 4.22Å; F51-T270 HydrophobicContact CE1-CG2 3.42Å; F51-T270 VanDerWaalsContact CE1-CG2 3.42Å; F51-T270 HydrophobicContact CE2-CG2 3.8Å; F51-T270 HydrophobicContact CZ-CG2 3.18Å; I266-T270 PolarHBondContact O-N 3.32Å; I266-T270 VanDerWaalsContact O-N 3.11Å; C267-T270 PolarHBondContact O-N 3.34Å; C267-T270 PolarHBondContact O-OG1 3.05Å; F268-T270 PolarHBondContact O-N 2.99Å
271	A	73.1	Confident	71.7	Confident	40 Å²	40	64.6 Å²	64.6	33%	0.331	35%	0.354	S	S	.	.	S	Bend	trans	-72.4	142.1	-178.9	0	0	0	0	0	111.3	K60 C267 F268	K60-A271 PolarHBondContact NZ-O 3.27Å; C267-A271 PolarHBondContact O-N 3.47Å; F268-A271 WeakPolarHBondContact O-CB 3.27Å; F268-A271 PolarHBondContact O-N 3.35Å
272	P	63	Low	69.5	Low	108 Å²	108	72 Å²	72	70%	0.701	39%	0.394	S	S	*	.	P	Polyproline II helix	trans	-59.9	145.9	179.2	25.3	-33.7	0	0	0	111	K274	P272-K274 PolarHBondContact O-N 3.09Å
273	L	63.4	Low	67.1	Low	95 Å²	95	77.6 Å²	77.6	50%	0.497	42%	0.424	S	S	.	.	P	Polyproline II helix	trans	-59.7	122.3	178.9	-166.7	95.7	0	0	0	109.8	D57 Y278	D57-L273 HydrophobicContact CB-CD1 4.02Å; D57-L273 WeakPolarHBondContact OD2-CD1 3.39Å; L273-Y278 HydrophobicContact CD1-CE2 4.19Å
274	K	62.4	Low	65	Low	137 Å²	137	82.5 Å²	82.5	60%	0.596	44%	0.44	S	S	*	.			trans	-102.9	114	169	-65.9	-175.4	179.4	-177	0	108.1	P272 E276 D277	P272-K274 PolarHBondContact O-N 3.09Å; K274-E276 PolarHBondContact O-N 3.07Å; K274-D277 WeakPolarHBondContact O-CB 3.35Å; K274-D277 PolarHBondContact O-N 2.88Å; K274-D277 VanDerWaalsContact O-N 3.07Å
275	L	55.8	Low	63.1	Low	144 Å²	144	86.9 Å²	86.9	75%	0.754	47%	0.47	S	S	*	.	G	3₁₀ helix	trans	-60.2	-28.4	-177.4	-158.9	78.3	0	0	0	112.1	D277 Y278	L275-D277 PolarHBondContact O-N 3.26Å; L275-Y278 PolarHBondContact O-N 2.66Å
276	E	59.3	Low	60.6	Low	176 Å²	176	93.3 Å²	93.3	82%	0.822	50%	0.5	S	S	*	.	G	3₁₀ helix	trans	-65	-15.1	175.8	-115	134.3	128.2	0	0	115.2	K274 Y278	K274-E276 PolarHBondContact O-N 3.07Å; E276-Y278 VanDerWaalsContact C-N 3.33Å
277	D	60.9	Low	58.3	Low	27 Å²	27	98 Å²	98	14%	0.144	53%	0.531	C	S	.	.	G	3₁₀ helix	trans	-80	-16.7	178.8	-71.5	-30.3	0	0	0	112.3	S203 W204 K274 L275	S203-D277 WeakPolarHBondContact CB-OD1 3.48Å; S203-D277 PolarHBondContact OG-OD1 2.88Å; W204-D277 PolarHBondContact NE1-O 3.39Å; K274-D277 WeakPolarHBondContact O-CB 3.35Å; K274-D277 PolarHBondContact O-N 2.88Å; K274-D277 VanDerWaalsContact O-N 3.07Å; L275-D277 PolarHBondContact O-N 3.26Å
278	Y	60.9	Low	56.5	Low	50 Å²	50	104.7 Å²	104.7	20%	0.196	55%	0.545	C	S	.	.	S	Bend	trans	-104.6	146.2	178.7	-64.6	-88.9	0	0	0	110.3	D57 W204 L273 L275 E276	D57-Y278 PolarHBondContact OD2-OH 3.46Å; W204-Y278 HydrophobicContact CH2-CE1 4.23Å; W204-Y278 HydrophobicContact CZ2-CD1 4.28Å; W204-Y278 AromaticContact CZ2-CE1 3.83Å; W204-Y278 HydrophobicContact CZ2-CE1 3.83Å; W204-Y278 AromaticContact CZ2-CZ 3.98Å; L273-Y278 HydrophobicContact CD1-CE2 4.19Å; L275-Y278 PolarHBondContact O-N 2.66Å; E276-Y278 VanDerWaalsContact C-N 3.33Å
279	P	57.9	Low	55.2	Low	38 Å²	38	110.6 Å²	110.6	25%	0.247	58%	0.578	C	S	.	*			trans	-55	136.9	169.4	24.8	-32.4	0	0	0	108	E281	P279-E281 PolarHBondContact O-N 2.94Å
280	P	54.8	Low	53.7	Low	105 Å²	105	116.6 Å²	116.6	68%	0.682	61%	0.609	S	S	*	*			trans	-55.5	115.9	179.9	21.8	-31.6	0	0	0	108.1	N282	P280-N282 VanDerWaalsContact C-N 3.27Å; P280-N282 PolarHBondContact O-N 3.39Å
281	E	51.5	Low	52.1	Low	116 Å²	116	121 Å²	121	54%	0.542	62%	0.621	S	S	.	*			trans	-65.4	98.5	166.7	-90.2	-172.8	152.6	0	0	106.5	P279 D283 F284	P279-E281 PolarHBondContact O-N 2.94Å; E281-D283 PolarHBondContact O-N 3.3Å; E281-F284 HydrophobicContact CB-CD2 4.18Å; E281-F284 PolarHBondContact O-N 3.1Å; E281-F284 WeakPolarHBondContact OE2-CE2 3.42Å
282	N	45.1	Very low	50.6	Low	156 Å²	156	127.7 Å²	127.7	83%	0.834	65%	0.646	S	S	*	*	T	Hydrogen-bonded Turn	trans	-61.9	5.5	170.5	-116	17.1	0	0	0	112.9	P280	P280-N282 VanDerWaalsContact C-N 3.27Å; P280-N282 PolarHBondContact O-N 3.39Å
283	D	43.3	Very low	49.8	Very low	117 Å²	117	128.1 Å²	128.1	63%	0.626	65%	0.646	S	S	*	*	T	Hydrogen-bonded Turn	trans	-90.5	-10	179.6	-71.3	-27.6	0	0	0	112.9	E281 C285	E281-D283 PolarHBondContact O-N 3.3Å; D283-C285 VanDerWaalsContact C-N 3.32Å; D283-C285 PolarHBondContact O-N 3.11Å
284	F	44.9	Very low	49.1	Very low	171 Å²	171	129.3 Å²	129.3	75%	0.75	66%	0.663	S	S	*	*	T	Hydrogen-bonded Turn	trans	-91.9	60.8	172.1	-75.3	-77.4	0	0	0	112.3	E281	E281-F284 HydrophobicContact CB-CD2 4.18Å; E281-F284 PolarHBondContact O-N 3.1Å; E281-F284 WeakPolarHBondContact OE2-CE2 3.42Å
285	C	46.7	Very low	48.4	Very low	124 Å²	124	125.5 Å²	125.5	84%	0.838	66%	0.662	S	S	*	*	T	Hydrogen-bonded Turn	trans	-173.9	43	150.6	-107.7	0	0	0	0	112.2	D283	D283-C285 VanDerWaalsContact C-N 3.32Å; D283-C285 PolarHBondContact O-N 3.11Å
286	Q	35.1	Very low	48.3	Very low	138 Å²	138	125 Å²	125	65%	0.645	67%	0.665	S	S	*	*			trans	-137.1	112.6	151.5	-82.5	-166.5	-23.9	0	0	108.8	R288	Q286-R288 VanDerWaalsContact C-N 3.29Å; Q286-R288 PolarHBondContact O-N 3.05Å
287	P	37.5	Very low	47.7	Very low	110 Å²	110	122.9 Å²	122.9	71%	0.714	66%	0.659	S	S	*	*			trans	-67	92.9	171.8	27.3	-30.3	0	0	0	108.4	L289 I290	P287-L289 PolarHBondContact O-N 2.92Å; P287-I290 HydrophobicContact CB-CG1 4.45Å
288	R	46	Very low	47.3	Very low	216 Å²	216	129 Å²	129	82%	0.815	69%	0.692	S	S	*	*	T	Hydrogen-bonded Turn	trans	-79.5	112.7	165.4	-69.8	-168.1	-179.3	-158.8	1.5	107.1	Q286	Q286-R288 VanDerWaalsContact C-N 3.29Å; Q286-R288 PolarHBondContact O-N 3.05Å
289	L	48.4	Very low	46.8	Very low	164 Å²	164	135 Å²	135	86%	0.859	72%	0.721	S	S	*	*	T	Hydrogen-bonded Turn	trans	74.7	69.7	-179.3	-102.5	84.2	0	0	0	115.9	P287 K291	P287-L289 PolarHBondContact O-N 2.92Å; L289-K291 VanDerWaalsContact C-N 3.31Å; L289-K291 PolarHBondContact O-N 2.78Å; L289-K291 VanDerWaalsContact O-N 3.16Å
290	I	43.6	Very low	46.4	Very low	136 Å²	136	136.8 Å²	136.8	70%	0.697	74%	0.739	S	S	*	*			trans	-66	106	135.8	-65.7	172.8	0	0	0	104.9	P287 Q292	P287-I290 HydrophobicContact CB-CG1 4.45Å; I290-Q292 VanDerWaalsContact C-N 3.33Å; I290-Q292 PolarHBondContact O-N 2.95Å
291	K	40.1	Very low	46.1	Very low	173 Å²	173	142.2 Å²	142.2	75%	0.752	75%	0.748	S	S	*	*			trans	-56.3	106.5	162.3	-162.7	179.6	-172.6	-177.2	0	104.8	L289 T293	L289-K291 VanDerWaalsContact C-N 3.31Å; L289-K291 PolarHBondContact O-N 2.78Å; L289-K291 VanDerWaalsContact O-N 3.16Å; K291-T293 PolarHBondContact O-N 2.92Å
292	Q	43.2	Very low	45.4	Very low	181 Å²	181	143.2 Å²	143.2	85%	0.846	76%	0.762	S	S	*	*			trans	-64	79.7	178.2	-162.6	175.2	8.2	0	0	107	I290 S294	I290-Q292 VanDerWaalsContact C-N 3.33Å; I290-Q292 PolarHBondContact O-N 2.95Å; Q292-S294 PolarHBondContact O-N 3.5Å
293	T	44.5	Very low	45.3	Very low	116 Å²	116	143.9 Å²	143.9	71%	0.712	76%	0.76	S	S	*	*			trans	-70.5	118.6	162.1	41.5	0	0	0	0	104	K291 G295	K291-T293 PolarHBondContact O-N 2.92Å; T293-G295 PolarHBondContact O-N 3.38Å
294	S	49.1	Very low	45	Very low	121 Å²	121	145.8 Å²	145.8	85%	0.846	77%	0.77	S	S	*	*			trans	-57	86.7	178.9	-44.3	0	0	0	0	109.3	Q292	Q292-S294 PolarHBondContact O-N 3.5Å
295	G	48.3	Very low	44.6	Very low	57 Å²	57	146.4 Å²	146.4	59%	0.588	78%	0.775	S	S	*	*			trans	-74.4	120.9	158.9	0	0	0	0	0	106.4	T293 D297	T293-G295 PolarHBondContact O-N 3.38Å; G295-D297 PolarHBondContact O-N 2.89Å
296	V	53.8	Low	44.2	Very low	133 Å²	133	148.5 Å²	148.5	81%	0.806	78%	0.777	S	S	*	*			trans	-64.9	105.9	168.8	172.2	0	0	0	0	106.5	N298	V296-N298 PolarHBondContact O-N 3.23Å
297	D	47.2	Very low	44.2	Very low	131 Å²	131	150.3 Å²	150.3	70%	0.701	79%	0.79	S	S	*	*			trans	-65.9	122	171.7	-77.8	-36.2	0	0	0	108.8	G295 H299	G295-D297 PolarHBondContact O-N 2.89Å; D297-H299 VanDerWaalsContact C-N 3.34Å; D297-H299 PolarHBondContact O-N 3.4Å
298	N	50.9	Low	43.9	Very low	155 Å²	155	154.5 Å²	154.5	83%	0.829	80%	0.8	S	S	*	*			trans	-71.2	90.7	172.7	-82.2	-31	0	0	0	109.2	V296 A300	V296-N298 PolarHBondContact O-N 3.23Å; N298-A300 PolarHBondContact O-N 3.34Å
299	H	50.6	Low	43.2	Very low	177 Å²	177	148.2 Å²	148.2	82%	0.819	80%	0.802	S	S	*	*	T	Hydrogen-bonded Turn	trans	-71.3	61.9	170.2	-84.5	-96.5	0	0	0	112	D297	D297-H299 VanDerWaalsContact C-N 3.34Å; D297-H299 PolarHBondContact O-N 3.4Å
300	A	49.1	Very low	42.2	Very low	76 Å²	76	144 Å²	144	63%	0.628	80%	0.799	S	S	*	*	T	Hydrogen-bonded Turn	trans	-101.7	-18.6	173.5	0	0	0	0	0	113.6	N298	N298-A300 PolarHBondContact O-N 3.34Å
301	Y	48.9	Very low	41.6	Very low	218 Å²	218	148 Å²	148	86%	0.855	81%	0.811	S	S	*	*	S	Bend	trans	-153	74.7	-173	-83.2	-84.4	0	0	0	112.7
302	T	38.1	Very low	41.1	Very low	137 Å²	137	143.5 Å²	143.5	84%	0.84	81%	0.814	S	S	*	*			trans	-164.4	92.5	148.8	-41	0	0	0	0	109.7
303	Q	41.7	Very low	40.7	Very low	171 Å²	171	142.5 Å²	142.5	80%	0.799	81%	0.814	S	S	*	*			trans	-162.4	100.3	151	-163.8	83.4	8.9	0	0	106.4
304	D	38.5	Very low	40.8	Very low	156 Å²	156	141.5 Å²	141.5	83%	0.834	81%	0.81	S	S	*	*			trans	-171.7	141.5	135.3	-91.2	-23.1	0	0	0	110.8
305	E	36.5	Very low	39.9	Very low	184 Å²	184	147.3 Å²	147.3	86%	0.86	81%	0.813	S	S	*	*			trans	87.9	72.3	166.3	-51.5	-165.7	160.8	0	0	119.7
306	I	37.6	Very low	39.3	Very low	169 Å²	169	152.5 Å²	152.5	87%	0.867	83%	0.827	S	S	*	*			trans	-136.6	97.2	130.7	-53.9	178.3	0	0	0	108.5
307	L	34	Very low	38.2	Very low	176 Å²	176	151.6 Å²	151.6	92%	0.921	83%	0.827	S	S	*	*			trans	-148.9	96.4	153.3	-91.9	175.3	0	0	0	110
308	Q	32.5	Very low	37.7	Very low	197 Å²	197	150.3 Å²	150.3	92%	0.921	83%	0.826	S	S	*	*			trans	-77.3	117.3	160.6	-107.3	179.2	-2	0	0	109.2
309	G	30	Very low	37	Very low	84 Å²	84	154 Å²	154	87%	0.866	83%	0.83	S	S	*	*			trans	76.6	116.3	135.8	0	0	0	0	0	119.7
310	G	28.9	Very low	36.2	Very low	77 Å²	77	150.9 Å²	150.9	79%	0.794	83%	0.828	S	S	*	*			trans	148.4	93	143.3	0	0	0	0	0	118
311	K	30.8	Very low	35.8	Very low	219 Å²	219	152.5 Å²	152.5	95%	0.952	83%	0.833	S	S	*	*			trans	43	120.5	144.4	-92.2	178.4	170.9	176.5	0	120.9
312	G	30	Very low	35.6	Very low	79 Å²	79	150.7 Å²	150.7	81%	0.814	83%	0.832	S	S	*	*			trans	123.1	99.5	132.8	0	0	0	0	0	117.6
313	D	34.2	Very low	35.5	Very low	159 Å²	159	153.6 Å²	153.6	85%	0.85	83%	0.833	S	S	*	*			trans	15.4	162.7	145	-126.9	14.2	0	0	0	123.2
314	P	46.9	Very low	35.6	Very low	95 Å²	95	155 Å²	155	62%	0.617	84%	0.84	S	S	*	*				-116.6	163.7	-109.8	34.3	-14.3	0	0	0	112
315	R	29.6	Very low	35.5	Very low	244 Å²	244	156.6 Å²	156.6	92%	0.921	85%	0.845	S	S	*	*			trans	-163.8	112.3	150.1	-112.8	174.4	-100.4	-161.6	-2.2	112
316	D	34.7	Very low	35.7	Very low	165 Å²	165	157.2 Å²	157.2	88%	0.882	84%	0.844	S	S	*	*			trans	-13.3	135.7	169	-62.6	-51.7	0	0	0	120.2
317	S	31.9	Very low	35.8	Very low	115 Å²	115	153.9 Å²	153.9	80%	0.804	84%	0.842	S	S	*	*			trans	-154.5	139.5	148	165.1	0	0	0	0	109.6
318	P	37.4	Very low	36.3	Very low	104 Å²	104	153.3 Å²	153.3	68%	0.675	84%	0.838	S	S	*	*			trans	-121.6	81.6	-137.4	35.8	-18.6	0	0	0	111.9
319	Y	34.7	Very low	36.8	Very low	231 Å²	231	152.3 Å²	152.3	91%	0.906	83%	0.834	S	S	*	*			trans	-150.4	100.7	164.9	-85.1	-79.7	0	0	0	109.8
320	S	34.6	Very low	37.4	Very low	112 Å²	112	154.6 Å²	154.6	78%	0.783	83%	0.833	S	S	*	*			trans	-118.7	116.9	168.9	-175.2	0	0	0	0	108.5
321	P	39.8	Very low	37.9	Very low	111 Å²	111	159 Å²	159	72%	0.721	83%	0.833	S	S	*	*			trans	-86	116.4	157.6	22	-9.5	0	0	0	108.7	F323	P321-F323 PolarHBondContact O-N 2.72Å
322	Q	45.2	Very low	38.4	Very low	180 Å²	180	153.9 Å²	153.9	84%	0.841	82%	0.816	S	S	*	*			trans	-57.4	116.8	168.8	-70.2	170	-33.8	0	0	110.6
323	F	36.9	Very low	39.2	Very low	197 Å²	197	158 Å²	158	86%	0.864	82%	0.819	S	S	*	*			trans	-136.9	107.1	153.7	-93.2	-82.6	0	0	0	108.7	P321 M325	P321-F323 PolarHBondContact O-N 2.72Å; F323-M325 PolarHBondContact O-N 2.96Å
324	Q	43.1	Very low	39.8	Very low	202 Å²	202	159.3 Å²	159.3	94%	0.944	82%	0.818	S	S	*	*			trans	-75.6	110.1	168.1	-75.9	-174	-7.3	0	0	108.5
325	M	36.7	Very low	40.2	Very low	189 Å²	189	160.1 Å²	160.1	93%	0.931	83%	0.826	S	S	*	*			trans	-91.9	115.9	169.1	-119.1	158.5	-170.8	0	0	109.5	F323	F323-M325 PolarHBondContact O-N 2.96Å
326	K	39.5	Very low	41.2	Very low	196 Å²	196	156 Å²	156	85%	0.852	82%	0.82	S	S	*	*	P	Polyproline II helix	trans	-61.1	127.2	176.9	-165	176	-170.3	-177.1	0	109.5	I328	K326-I328 PolarHBondContact O-N 2.82Å
327	A	41.5	Very low	42.1	Very low	99 Å²	99	153.8 Å²	153.8	82%	0.818	82%	0.815	S	S	*	*	P	Polyproline II helix	trans	-63.7	127.1	175.4	0	0	0	0	0	110.4
328	I	42.8	Very low	43.2	Very low	165 Å²	165	159.4 Å²	159.4	85%	0.846	82%	0.819	S	S	*	*	P	Polyproline II helix	trans	-84	129.7	173.1	-70.2	167	0	0	0	108	K326	K326-I328 PolarHBondContact O-N 2.82Å
329	E	43.8	Very low	43.9	Very low	176 Å²	176	160.6 Å²	160.6	82%	0.822	83%	0.826	S	S	*	*	P	Polyproline II helix	trans	-62.7	145.7	176.4	-82	169.1	142.4	0	0	112.2	Q331	E329-Q331 PolarHBondContact O-N 2.91Å
330	P	43	Very low	44.9	Very low	132 Å²	132	159.4 Å²	159.4	86%	0.857	83%	0.826	S	S	*	*			trans	-80.2	110.3	-177.3	32.3	-29.5	0	0	0	109.1
331	Q	39.8	Very low	45.8	Very low	168 Å²	168	158.8 Å²	158.8	79%	0.785	83%	0.827	S	S	*	*			trans	-130.3	126	166.4	-124.8	-169.7	5.9	0	0	112.6	E329	E329-Q331 PolarHBondContact O-N 2.91Å
332	N	41.3	Very low	46.4	Very low	112 Å²	112	165.3 Å²	165.3	60%	0.599	84%	0.837	S	S	*	*			trans	93.7	102.8	157.7	-54.9	-27.3	0	0	0	117.6	F334	N332-F334 HydrophobicContact CB-CE2 4.07Å; N332-F334 WeakPolarHBondContact O-CD2 3.18Å; N332-F334 PolarHBondContact O-N 3.46Å
333	D	46.7	Very low	47.2	Very low	166 Å²	166	162.5 Å²	162.5	89%	0.888	83%	0.833	S	S	*	*			trans	-51.4	106.6	158.3	-85.7	-36.3	0	0	0	111
334	F	46.7	Very low	48.2	Very low	187 Å²	187	156.6 Å²	156.6	82%	0.82	82%	0.816	S	S	*	*			trans	-98.2	94	162.7	-74.8	-81.4	0	0	0	109.1	N332	N332-F334 HydrophobicContact CB-CE2 4.07Å; N332-F334 WeakPolarHBondContact O-CD2 3.18Å; N332-F334 PolarHBondContact O-N 3.46Å
335	S	55.3	Low	48.9	Very low	111 Å²	111	152.8 Å²	152.8	78%	0.776	81%	0.809	S	S	*	*	P	Polyproline II helix	trans	-81.6	119.3	169.7	44.1	0	0	0	0	110.2
336	I	51	Low	49.8	Very low	158 Å²	158	152.1 Å²	152.1	81%	0.81	80%	0.797	S	S	*	*	P	Polyproline II helix	trans	-69	128.3	174.1	-57	171.3	0	0	0	108.5	R338	I336-R338 PolarHBondContact O-N 2.83Å
337	P	52.4	Low	50.6	Low	119 Å²	119	150 Å²	150	77%	0.773	79%	0.79	S	S	*	*	P	Polyproline II helix	trans	-68.9	121.8	179.6	-12.4	26.2	0	0	0	110.7
338	R	55.7	Low	51.2	Low	233 Å²	233	152.6 Å²	152.6	88%	0.879	79%	0.79	S	S	*	*	P	Polyproline II helix	trans	-72.5	139.7	168.2	-70.1	-166.2	-158.7	-176.4	6.8	110.3	I336 K340	I336-R338 PolarHBondContact O-N 2.83Å; R338-K340 PolarHBondContact O-N 3.13Å
339	P	52	Low	51.7	Low	128 Å²	128	154.1 Å²	154.1	83%	0.831	79%	0.786	S	S	*	*	P	Polyproline II helix	trans	-65.1	129.1	174.5	24.5	-30.3	0	0	0	110.7	A341	P339-A341 PolarHBondContact O-N 2.9Å
340	K	54.8	Low	52.5	Low	207 Å²	207	151.9 Å²	151.9	90%	0.9	79%	0.785	S	S	*	*	P	Polyproline II helix	trans	-69.6	124.6	173	-70.9	-176.6	178	-179.7	0	109.3	R338 R342	R338-K340 PolarHBondContact O-N 3.13Å; K340-R342 PolarHBondContact O-N 3.21Å
341	A	54.1	Low	53	Low	98 Å²	98	148.5 Å²	148.5	81%	0.81	77%	0.774	S	S	*	*	P	Polyproline II helix	trans	-62.1	127.8	170.9	0	0	0	0	0	109.6	P339 T343	P339-A341 PolarHBondContact O-N 2.9Å; A341-T343 PolarHBondContact O-N 2.88Å
342	R	53.1	Low	53.7	Low	248 Å²	248	144.5 Å²	144.5	94%	0.936	78%	0.778	S	S	*	*	P	Polyproline II helix	trans	-64.1	129.6	170.8	-99	-179.7	169.4	174.9	-3.4	109	K340	K340-R342 PolarHBondContact O-N 3.21Å
343	T	61.3	Low	54	Low	121 Å²	121	149 Å²	149	74%	0.742	79%	0.792	S	S	*	*	P	Polyproline II helix	trans	-64.6	138.9	170.3	30.4	0	0	0	0	110.6	A341	A341-T343 PolarHBondContact O-N 2.88Å
344	S	57.5	Low	54	Low	73 Å²	73	144.6 Å²	144.6	51%	0.51	79%	0.786	S	S	.	*	P	Polyproline II helix	trans	-57.9	140.6	178.9	168.8	0	0	0	0	111.7	Y346	S344-Y346 PolarHBondContact O-N 3.38Å
345	P	58.3	Low	54.1	Low	123 Å²	123	141.6 Å²	141.6	80%	0.799	79%	0.786	S	S	*	*	T	Hydrogen-bonded Turn	trans	-67.3	-4.5	-178.1	-16.5	30	0	0	0	115.4
346	Y	55	Low	53.5	Low	174 Å²	174	149.1 Å²	149.1	68%	0.682	81%	0.812	S	S	*	*	T	Hydrogen-bonded Turn	trans	-105.1	15.5	-173.4	-67.6	-78.5	0	0	0	113.9	S344 D348 Y349	S344-Y346 PolarHBondContact O-N 3.38Å; Y346-D348 PolarHBondContact O-N 3.07Å; Y346-D348 VanDerWaalsContact O-N 3.14Å; Y346-Y349 HydrophobicContact CD1-CD2 4.48Å; Y346-Y349 PolarHBondContact O-N 3.07Å
347	H	57.3	Low	53.6	Low	153 Å²	153	148.7 Å²	148.7	71%	0.708	81%	0.812	S	S	*	*	T	Hydrogen-bonded Turn	trans	-66.3	-17.8	-172.4	-138.8	-46.2	0	0	0	114.3
348	D	53.1	Low	53.7	Low	152 Å²	152	150.3 Å²	150.3	81%	0.813	81%	0.814	S	S	*	*	T	Hydrogen-bonded Turn	trans	-110.5	13.5	-178.4	-67.8	-35.3	0	0	0	114.4	Y346 T350	Y346-D348 PolarHBondContact O-N 3.07Å; Y346-D348 VanDerWaalsContact O-N 3.14Å; D348-T350 VanDerWaalsContact C-N 3.32Å; D348-T350 PolarHBondContact O-N 3.29Å
349	Y	53.8	Low	53.6	Low	197 Å²	197	145.7 Å²	145.7	77%	0.773	81%	0.81	S	S	*	*			trans	-77	83.4	177.2	-137	-91.2	0	0	0	110.8	Y346 G351	Y346-Y349 HydrophobicContact CD1-CD2 4.48Å; Y346-Y349 PolarHBondContact O-N 3.07Å; Y349-G351 PolarHBondContact O-N 3.34Å
350	T	59.9	Low	53.7	Low	130 Å²	130	146.7 Å²	146.7	80%	0.798	81%	0.809	S	S	*	*			trans	-77.7	105.5	168.8	45.4	0	0	0	0	108.9	D348 G352	D348-T350 VanDerWaalsContact C-N 3.32Å; D348-T350 PolarHBondContact O-N 3.29Å; T350-G352 PolarHBondContact O-N 3.45Å
351	G	53	Low	53.6	Low	61 Å²	61	142.9 Å²	142.9	63%	0.629	80%	0.804	S	S	*	*			trans	-50.9	133.9	176.3	0	0	0	0	0	111.7	Y349 K353	Y349-G351 PolarHBondContact O-N 3.34Å; G351-K353 PolarHBondContact O-N 3.04Å
352	G	55.4	Low	53.6	Low	84 Å²	84	145.9 Å²	145.9	87%	0.866	80%	0.803	S	S	*	*			trans	-48.2	121.5	-170.6	0	0	0	0	0	114.3	T350	T350-G352 PolarHBondContact O-N 3.45Å
353	K	47.3	Very low	53.6	Low	205 Å²	205	138.6 Å²	138.6	89%	0.891	79%	0.794	S	S	*	*			trans	-115.9	110.7	152.5	-73.4	-175.9	177.3	179.6	0	106.5	G351	G351-K353 PolarHBondContact O-N 3.04Å
354	G	47.2	Very low	53	Low	74 Å²	74	140 Å²	140	76%	0.763	80%	0.798	S	S	*	*			trans	-73.1	175.2	177.8	0	0	0	0	0	112.7
355	P	49.1	Very low	52.6	Low	125 Å²	125	145.6 Å²	145.6	81%	0.812	82%	0.822	S	S	*	*			trans	-108.3	129.6	165.5	32.8	-19.7	0	0	0	112.1
356	M	42.2	Very low	52.1	Low	269 Å²	269	147.6 Å²	147.6	100%	1.325	82%	0.824	S	S	*	*			trans	59	0	155	-66.2	-175	-178	0	0	120.2

Retrieved 356 of 356 residues in 210.3 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).