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Nociceptin receptor

G-protein coupled opioid receptor that functions as a receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.

AlphaFold DB , UniProt , Accession A0A093H0N6, Species STRCA (Struthio camelus australis), Gene n/a, Length 368 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	39.5	Very low	36.4	Very low	243 Å²	243	158.2 Å²	158.2	100%	1.197	85%	0.845	S	S	*	*				0	93.8	0	-84.9	178.8	176	0	0	105.8
2	D	31.6	Very low	36.7	Very low	151 Å²	151	153.8 Å²	153.8	81%	0.807	82%	0.822	S	S	*	*			trans	-72.3	145.2	-179.3	-58.3	-58.3	0	0	0	110.8
3	P	34.2	Very low	37.2	Very low	128 Å²	128	149.7 Å²	149.7	83%	0.831	81%	0.809	S	S	*	*			trans	-77.2	121.1	164.5	-2.1	19	0	0	0	110	F5	P3-F5 PolarHBondContact O-N 3.21Å
4	L	33.4	Very low	37.5	Very low	155 Å²	155	146.9 Å²	146.9	81%	0.812	79%	0.793	S	S	*	*			trans	-77.1	108.3	169.1	-139.3	89.2	0	0	0	108.1
5	F	33.9	Very low	37.6	Very low	184 Å²	184	144.9 Å²	144.9	81%	0.807	78%	0.781	S	S	*	*			trans	154	113.7	143	-87.3	-69.3	0	0	0	110.1	P3	P3-F5 PolarHBondContact O-N 3.21Å
6	P	35.3	Very low	37.8	Very low	117 Å²	117	148.8 Å²	148.8	76%	0.76	78%	0.781	S	S	*	*			trans	-80.2	135.2	-177.1	29.7	-31.2	0	0	0	112.4	H8	P6-H8 PolarHBondContact O-N 3.18Å
7	A	41.3	Very low	37.8	Very low	100 Å²	100	148.6 Å²	148.6	83%	0.826	77%	0.772	S	S	*	*			trans	-68.6	92.1	165.5	0	0	0	0	0	109.7
8	H	39.3	Very low	37.8	Very low	155 Å²	155	147.6 Å²	147.6	72%	0.718	77%	0.768	S	S	*	*			trans	-155.9	62.6	168.1	-113.3	-63.1	0	0	0	110.9	P6	P6-H8 PolarHBondContact O-N 3.18Å
9	I	35.7	Very low	38	Very low	167 Å²	167	146.5 Å²	146.5	86%	0.856	76%	0.762	S	S	*	*			trans	-143.5	67.2	161.2	-49.9	177.9	0	0	0	107.5
10	L	35.2	Very low	37.9	Very low	171 Å²	171	146.3 Å²	146.3	90%	0.895	76%	0.762	S	S	*	*	S	Bend	trans	-155.1	31.8	171.3	-121	136.4	0	0	0	113.6
11	E	41.6	Very low	37.7	Very low	169 Å²	169	145.5 Å²	145.5	79%	0.79	76%	0.759	S	S	*	*			trans	-139	47.5	171.4	-72.6	-169.9	147	0	0	111.2	P13	E11-P13 WeakPolarHBondContact O-CD 3.44Å
12	D	39	Very low	37.4	Very low	106 Å²	106	138.6 Å²	138.6	57%	0.567	74%	0.735	S	S	*	*			trans	-97.9	107.7	167.9	-161	-26.8	0	0	0	110.2	D14 L15	D12-D14 PolarHBondContact O-N 3.25Å; D12-D14 PolarHBondContact OD1-N 3.08Å; D12-L15 PolarHBondContact O-N 3.2Å
13	P	43.5	Very low	37.5	Very low	100 Å²	100	136 Å²	136	65%	0.649	73%	0.728	S	S	*	*	H	α-helix	trans	-68	-16.2	-177.9	25.4	-31.9	0	0	0	114.1	E11	E11-P13 WeakPolarHBondContact O-CD 3.44Å
14	D	40.9	Very low	37.2	Very low	110 Å²	110	138 Å²	138	59%	0.588	73%	0.729	S	S	*	*	H	α-helix	trans	-79.8	-27.6	179.9	-78.4	-34.5	0	0	0	112.9	D12 K17 L18	D12-D14 PolarHBondContact O-N 3.25Å; D12-D14 PolarHBondContact OD1-N 3.08Å; D14-K17 PolarHBondContact O-N 3.09Å; D14-L18 PolarHBondContact O-N 2.76Å
15	L	39.7	Very low	37.2	Very low	117 Å²	117	138.3 Å²	138.3	61%	0.613	73%	0.73	S	S	*	*	H	α-helix	trans	-72	-31	175.8	-163.3	71.1	0	0	0	112.1	D12 K17 L18 L19	D12-L15 PolarHBondContact O-N 3.2Å; L15-K17 VanDerWaalsContact C-N 3.29Å; L15-K17 PolarHBondContact O-N 3.47Å; L15-L18 PolarHBondContact O-N 3.01Å; L15-L19 PolarHBondContact O-N 2.9Å
16	R	40.1	Very low	36.7	Very low	208 Å²	208	136.3 Å²	136.3	79%	0.785	73%	0.728	S	S	*	*	H	α-helix	trans	-69.7	-28.7	175.2	-133.4	177.8	-162.3	-104.4	3.2	112.1	N20	R16-N20 PolarHBondContact O-N 3.3Å
17	K	37.6	Very low	36.4	Very low	145 Å²	145	137 Å²	137	63%	0.63	73%	0.725	S	S	*	*	H	α-helix	trans	-76	-37	177.9	-150.8	176.5	-176.9	-177.4	0	111.8	D14 L15 L19 N20 D21	D14-K17 PolarHBondContact O-N 3.09Å; L15-K17 VanDerWaalsContact C-N 3.29Å; L15-K17 PolarHBondContact O-N 3.47Å; K17-L19 PolarHBondContact O-N 3.21Å; K17-N20 PolarHBondContact O-N 2.94Å; K17-D21 PolarHBondContact O-N 3.49Å
18	L	39.1	Very low	35.8	Very low	131 Å²	131	136.8 Å²	136.8	69%	0.686	72%	0.717	S	S	*	*	H	α-helix	trans	-66.9	-31.3	174.8	-83.7	158.7	0	0	0	113.7	D14 L15	D14-L18 PolarHBondContact O-N 2.76Å; L15-L18 PolarHBondContact O-N 3.01Å
19	L	41	Very low	35.2	Very low	126 Å²	126	138.5 Å²	138.5	66%	0.66	72%	0.723	S	S	*	*	H	α-helix	trans	-73.1	-33.2	174.6	-75.5	166.4	0	0	0	112.5	L15 K17 S22	L15-L19 PolarHBondContact O-N 2.9Å; K17-L19 PolarHBondContact O-N 3.21Å; L19-S22 PolarHBondContact O-OG 3.5Å
20	N	37	Very low	34.7	Very low	143 Å²	143	136.4 Å²	136.4	77%	0.765	71%	0.712	S	S	*	*	H	α-helix	trans	-76.1	-20.2	-178.9	-107.6	14.8	0	0	0	114.4	R16 K17 S22	R16-N20 PolarHBondContact O-N 3.3Å; K17-N20 PolarHBondContact O-N 2.94Å; N20-S22 VanDerWaalsContact C-N 3.34Å
21	D	32.9	Very low	34.3	Very low	129 Å²	129	132.5 Å²	132.5	69%	0.69	70%	0.697	S	S	*	*	T	Hydrogen-bonded Turn	trans	-84.8	-1.3	-179	-94.7	-16.7	0	0	0	114.3	K17 S23	K17-D21 PolarHBondContact O-N 3.49Å; D21-S23 PolarHBondContact O-N 2.87Å
22	S	33.3	Very low	33.7	Very low	99 Å²	99	129 Å²	129	69%	0.692	69%	0.691	S	S	*	*			trans	-82	53.7	174.5	57.5	0	0	0	0	113	L19 N20 M24	L19-S22 PolarHBondContact O-OG 3.5Å; N20-S22 VanDerWaalsContact C-N 3.34Å; S22-M24 VanDerWaalsContact C-N 3.3Å; S22-M24 PolarHBondContact O-N 2.93Å; S22-M24 VanDerWaalsContact O-N 3.11Å
23	S	33	Very low	33.1	Very low	96 Å²	96	130.5 Å²	130.5	67%	0.671	70%	0.699	S	S	*	*			trans	-82.3	52.9	178.6	57.4	0	0	0	0	113.8	D21	D21-S23 PolarHBondContact O-N 2.87Å
24	M	28.9	Very low	32.5	Very low	171 Å²	171	134 Å²	134	84%	0.842	70%	0.7	S	S	*	*			trans	-118	22.3	179.1	-83.1	-113.1	73.9	0	0	115.3	S22	S22-M24 VanDerWaalsContact C-N 3.3Å; S22-M24 PolarHBondContact O-N 2.93Å; S22-M24 VanDerWaalsContact O-N 3.11Å
25	L	32.4	Very low	32.1	Very low	161 Å²	161	137.3 Å²	137.3	84%	0.843	71%	0.709	S	S	*	*			trans	-137.6	70.9	165.4	-73.9	171.2	0	0	0	110.6	L27	L25-L27 PolarHBondContact O-N 2.83Å
26	N	23.9	Very low	31.7	Very low	142 Å²	142	138.3 Å²	138.3	76%	0.759	72%	0.715	S	S	*	*			trans	-66.2	95.2	164.6	-98.9	-29.6	0	0	0	109.1	S28	N26-S28 PolarHBondContact O-N 3.25Å
27	L	28.8	Very low	31.3	Very low	132 Å²	132	136.6 Å²	136.6	69%	0.691	72%	0.721	S	S	*	*			trans	-86.2	39.3	173	-144.4	82.4	0	0	0	111.6	L25 F29 L30	L25-L27 PolarHBondContact O-N 2.83Å; L27-F29 PolarHBondContact O-N 3.46Å; L27-L30 HydrophobicContact CD2-CD1 3.68Å; L27-L30 HydrophobicContact CG-CD1 4.26Å
28	S	27.8	Very low	30.9	Very low	94 Å²	94	133.4 Å²	133.4	66%	0.657	73%	0.73	S	S	*	*	T	Hydrogen-bonded Turn	trans	-79	11.2	178.5	51.7	0	0	0	0	114	N26	N26-S28 PolarHBondContact O-N 3.25Å
29	F	26.8	Very low	30.7	Very low	192 Å²	192	134.2 Å²	134.2	84%	0.842	74%	0.74	S	S	*	*	T	Hydrogen-bonded Turn	trans	-97.2	1.4	179.5	-87.4	-83.1	0	0	0	114.7	L27	L27-F29 PolarHBondContact O-N 3.46Å
30	L	26.6	Very low	30.7	Very low	123 Å²	123	131.2 Å²	131.2	64%	0.644	74%	0.74	S	S	*	*	S	Bend	trans	-96.6	127.4	176.8	-68.4	175.3	0	0	0	110.9	L27 S32	L27-L30 HydrophobicContact CD2-CD1 3.68Å; L27-L30 HydrophobicContact CG-CD1 4.26Å; L30-S32 PolarHBondContact O-N 2.95Å
31	P	25.7	Very low	31.1	Very low	88 Å²	88	132.2 Å²	132.2	57%	0.571	75%	0.745	S	S	*	*			trans	-59	129.5	179.5	-19.6	30	0	0	0	111.1	N33	P31-N33 PolarHBondContact O-N 2.95Å
32	S	29.8	Very low	31.7	Very low	95 Å²	95	130.1 Å²	130.1	66%	0.664	74%	0.741	S	S	*	*	G	3₁₀ helix	trans	-61.8	3.7	-178.5	51	0	0	0	0	115.7	L30	L30-S32 PolarHBondContact O-N 2.95Å
33	N	25.9	Very low	33	Very low	138 Å²	138	131 Å²	131	74%	0.738	73%	0.732	S	S	*	*	G	3₁₀ helix	trans	-93.2	3.6	-174.1	-61.5	-4	0	0	0	113.2	P31	P31-N33 PolarHBondContact O-N 2.95Å
34	W	30.9	Very low	34.8	Very low	175 Å²	175	127.3 Å²	127.3	66%	0.663	71%	0.705	S	S	*	*	G	3₁₀ helix	trans	-92.9	-6.1	175.8	-84.2	46.3	0	0	0	114	I50	W34-I50 HydrophobicContact CH2-CD1 3.94Å; W34-I50 HydrophobicContact CZ3-CD1 4.21Å
35	F	33.6	Very low	37.4	Very low	178 Å²	178	121.8 Å²	121.8	78%	0.781	68%	0.682	S	S	*	*	S	Bend	trans	-104.7	-5.7	-171.7	-85.6	-79.1	0	0	0	115.7
36	N	30.4	Very low	39.8	Very low	139 Å²	139	118.8 Å²	118.8	74%	0.743	67%	0.666	S	S	*	*	S	Bend	trans	-131.9	93.4	-176.7	-79.9	-23.4	0	0	0	112.7
37	N	31.8	Very low	42.8	Very low	171 Å²	171	113.3 Å²	113.3	91%	0.914	64%	0.644	S	S	*	*				161	112.3	127.3	-91.5	-8.6	0	0	0	110
38	G	28.6	Very low	45.4	Very low	78 Å²	78	109.8 Å²	109.8	80%	0.804	63%	0.625	S	S	*	*			trans	170.9	88.5	173.1	0	0	0	0	0	110.5
39	T	35.9	Very low	48.2	Very low	148 Å²	148	106.5 Å²	106.5	91%	0.908	60%	0.598	S	S	*	*			trans	-60.1	130.5	169.7	44.5	0	0	0	0	111.4
40	G	40.9	Very low	51.2	Low	63 Å²	63	100.3 Å²	100.3	65%	0.649	57%	0.574	S	S	*	*	S	Bend	trans	88.9	117.7	160.1	0	0	0	0	0	116
41	D	44.3	Very low	54.2	Low	164 Å²	164	98.6 Å²	98.6	88%	0.877	57%	0.569	S	S	*	*			trans	57.9	67.2	151.3	-53.4	-20.6	0	0	0	119.1
42	S	46.9	Very low	57.1	Low	86 Å²	86	95 Å²	95	60%	0.601	54%	0.544	S	S	*	.			trans	-146.1	106.4	156.9	65.3	0	0	0	0	112.4	L44	S42-L44 PolarHBondContact O-N 3.25Å
43	F	60.6	Low	60	Low	116 Å²	116	92.4 Å²	92.4	51%	0.509	52%	0.524	S	S	.	.	S	Bend	trans	-66.4	4.9	-173.5	-143.6	-97.8	0	0	0	115.7	E291 L296	F43-E291 VanDerWaalsContact CZ-O 3.26Å; F43-E291 WeakPolarHBondContact CZ-O 3.32Å; F43-L296 HydrophobicContact CB-CD2 4.2Å; F43-L296 HydrophobicContact CD1-CD2 3.64Å; F43-L296 HydrophobicContact CG-CD2 4.37Å
44	L	70.6	Confident	63.1	Low	20 Å²	20	89.4 Å²	89.4	11%	0.105	51%	0.511	C	S	.	.	S	Bend	trans	-139	125.9	-177.5	-88.8	156.1	0	0	0	111	S42 I48 K49 L296 A297	S42-L44 PolarHBondContact O-N 3.25Å; L44-I48 HydrophobicContact CD2-CB 4.25Å; L44-I48 HydrophobicContact CD2-CG2 3.75Å; L44-K49 HydrophobicContact CB-CG 4.05Å; L44-L296 HydrophobicContact CD1-CD2 3.49Å; L44-L296 VanDerWaalsContact CD1-CD2 3.49Å; L44-L296 HydrophobicContact CD1-CG 3.86Å; L44-L296 HydrophobicContact CD2-CD2 4.39Å; L44-L296 HydrophobicContact CD2-CG 4.37Å; L44-L296 HydrophobicContact CG-CD2 3.63Å; L44-L296 HydrophobicContact CG-CG 4.1Å; L44-A297 HydrophobicContact CD2-CB 4.43Å
45	P	82.4	Confident	66	Low	54 Å²	54	83.8 Å²	83.8	35%	0.351	50%	0.495	S	S	.	.			trans	-54.5	139.4	172	-24.7	31.2	0	0	0	112.4	G47 I48 K49	P45-G47 PolarHBondContact O-N 3.48Å; P45-G47 VanDerWaalsContact O-N 3.11Å; P45-I48 HydrophobicContact CB-CD1 4.44Å; P45-I48 HydrophobicContact CB-CG1 4.3Å; P45-I48 HydrophobicContact CG-CD1 4.07Å; P45-I48 HydrophobicContact CG-CG1 4.47Å; P45-I48 PolarHBondContact O-N 3.4Å; P45-K49 PolarHBondContact O-N 3.46Å
46	L	84.1	Confident	68.8	Low	98 Å²	98	75.8 Å²	75.8	51%	0.513	46%	0.46	S	S	.	.	H	α-helix	trans	-53.1	-37.5	-179.2	-178.5	64	0	0	0	112.9	I48 K49 I50 F110	L46-I48 VanDerWaalsContact C-N 3.31Å; L46-I48 PolarHBondContact O-N 3.3Å; L46-K49 PolarHBondContact O-N 2.96Å; L46-I50 HydrophobicContact CD1-CD1 4.25Å; L46-I50 HydrophobicContact CD1-CG1 4.38Å; L46-I50 HydrophobicContact CD2-CD1 4.46Å; L46-I50 HydrophobicContact CG-CD1 3.89Å; L46-I50 HydrophobicContact CG-CG1 4.43Å; L46-I50 WeakPolarHBondContact O-CG1 3.44Å; L46-I50 PolarHBondContact O-N 3.39Å; L46-F110 HydrophobicContact CD1-CE2 4.28Å
47	G	85.8	Confident	71.8	Confident	28 Å²	28	72 Å²	72	29%	0.289	45%	0.445	S	S	.	.	H	α-helix	trans	-62.2	-35	177.3	0	0	0	0	0	113.9	P45 T51	P45-G47 PolarHBondContact O-N 3.48Å; P45-G47 VanDerWaalsContact O-N 3.11Å; G47-T51 WeakPolarHBondContact O-CB 3.36Å; G47-T51 PolarHBondContact O-N 2.92Å; G47-T51 VanDerWaalsContact O-N 3.08Å; G47-T51 PolarHBondContact O-OG1 2.92Å
48	I	84.6	Confident	74.7	Confident	57 Å²	57	68.6 Å²	68.6	29%	0.292	43%	0.425	S	S	.	.	H	α-helix	trans	-72	-45.3	176.9	-59.9	-175.1	0	0	0	109.6	L44 P45 L46 I50 T51 I52 A297	L44-I48 HydrophobicContact CD2-CB 4.25Å; L44-I48 HydrophobicContact CD2-CG2 3.75Å; P45-I48 HydrophobicContact CB-CD1 4.44Å; P45-I48 HydrophobicContact CB-CG1 4.3Å; P45-I48 HydrophobicContact CG-CD1 4.07Å; P45-I48 HydrophobicContact CG-CG1 4.47Å; P45-I48 PolarHBondContact O-N 3.4Å; L46-I48 VanDerWaalsContact C-N 3.31Å; L46-I48 PolarHBondContact O-N 3.3Å; I48-I50 PolarHBondContact O-N 3.33Å; I48-T51 WeakPolarHBondContact O-CB 3.3Å; I48-T51 PolarHBondContact O-N 3.04Å; I48-T51 VanDerWaalsContact O-N 3.14Å; I48-I52 HydrophobicContact CG2-CD1 3.79Å; I48-I52 HydrophobicContact CG2-CG1 4.4Å; I48-I52 WeakPolarHBondContact O-CG1 3.33Å; I48-I52 PolarHBondContact O-N 3.08Å; I48-A297 HydrophobicContact CD1-CB 3.94Å; I48-A297 HydrophobicContact CG2-CB 4.2Å
49	K	86.3	Confident	77.7	Confident	25 Å²	25	65.4 Å²	65.4	11%	0.109	39%	0.39	C	S	.	.	H	α-helix	trans	-55.8	-49.2	175.5	-65	-173.9	172.3	-166.9	0	112	L44 P45 L46 T51 I52 V53 F110	L44-K49 HydrophobicContact CB-CG 4.05Å; P45-K49 PolarHBondContact O-N 3.46Å; L46-K49 PolarHBondContact O-N 2.96Å; K49-T51 VanDerWaalsContact C-N 3.3Å; K49-T51 PolarHBondContact O-N 3.3Å; K49-I52 PolarHBondContact O-N 3.36Å; K49-V53 WeakPolarHBondContact O-CG2 3.35Å; K49-V53 PolarHBondContact O-N 3.43Å; K49-F110 HydrophobicContact CB-CD2 4.38Å; K49-F110 PolarHBondContact NZ-O 3.02Å
50	I	89.3	Confident	80.5	Confident	63 Å²	63	59 Å²	59	32%	0.323	35%	0.351	S	S	.	.	H	α-helix	trans	-59.3	-44.4	177.3	-68.7	168.8	0	0	0	110.5	W34 L46 I48 I52 V53 V54 F110	W34-I50 HydrophobicContact CH2-CD1 3.94Å; W34-I50 HydrophobicContact CZ3-CD1 4.21Å; L46-I50 HydrophobicContact CD1-CD1 4.25Å; L46-I50 HydrophobicContact CD1-CG1 4.38Å; L46-I50 HydrophobicContact CD2-CD1 4.46Å; L46-I50 HydrophobicContact CG-CD1 3.89Å; L46-I50 HydrophobicContact CG-CG1 4.43Å; L46-I50 WeakPolarHBondContact O-CG1 3.44Å; L46-I50 PolarHBondContact O-N 3.39Å; I48-I50 PolarHBondContact O-N 3.33Å; I50-I52 PolarHBondContact O-N 3.36Å; I50-V53 PolarHBondContact O-N 3.01Å; I50-V54 HydrophobicContact CG2-CG2 4.33Å; I50-V54 VanDerWaalsContact O-CG2 3.27Å; I50-V54 WeakPolarHBondContact O-CG2 3.24Å; I50-V54 PolarHBondContact O-N 2.86Å; I50-F110 HydrophobicContact CG1-CE2 4.26Å
51	T	89.4	Confident	82.9	Confident	87 Å²	87	61.2 Å²	61.2	53%	0.534	35%	0.347	S	S	.	.	H	α-helix	trans	-60.7	-45.8	179.9	-61.3	0	0	0	0	111.5	G47 I48 K49 V54 V55	G47-T51 WeakPolarHBondContact O-CB 3.36Å; G47-T51 PolarHBondContact O-N 2.92Å; G47-T51 VanDerWaalsContact O-N 3.08Å; G47-T51 PolarHBondContact O-OG1 2.92Å; I48-T51 WeakPolarHBondContact O-CB 3.3Å; I48-T51 PolarHBondContact O-N 3.04Å; I48-T51 VanDerWaalsContact O-N 3.14Å; K49-T51 VanDerWaalsContact C-N 3.3Å; K49-T51 PolarHBondContact O-N 3.3Å; T51-V54 PolarHBondContact O-N 3.35Å; T51-V55 VanDerWaalsContact O-CG2 3.32Å; T51-V55 WeakPolarHBondContact O-CG2 3.44Å; T51-V55 PolarHBondContact O-N 3.01Å
52	I	86.6	Confident	85.2	Confident	13 Å²	13	56.9 Å²	56.9	7%	0.067	33%	0.326	C	S	.	.	H	α-helix	trans	-61.2	-47.3	178.4	-65.3	158.7	0	0	0	110.8	I48 K49 I50 V54 V55 Y56 T109 C300	I48-I52 HydrophobicContact CG2-CD1 3.79Å; I48-I52 HydrophobicContact CG2-CG1 4.4Å; I48-I52 WeakPolarHBondContact O-CG1 3.33Å; I48-I52 PolarHBondContact O-N 3.08Å; K49-I52 PolarHBondContact O-N 3.36Å; I50-I52 PolarHBondContact O-N 3.36Å; I52-V54 VanDerWaalsContact C-N 3.32Å; I52-V54 PolarHBondContact O-N 3.4Å; I52-V55 PolarHBondContact O-N 3.14Å; I52-V55 VanDerWaalsContact O-N 3.16Å; I52-Y56 HydrophobicContact CG2-CD1 4.14Å; I52-Y56 HydrophobicContact CG2-CD2 4.3Å; I52-Y56 HydrophobicContact CG2-CE1 3.83Å; I52-Y56 HydrophobicContact CG2-CE2 3.98Å; I52-Y56 HydrophobicContact CG2-CG 4.37Å; I52-Y56 PolarHBondContact O-N 3.4Å; I52-T109 HydrophobicContact CB-CG2 4.43Å; I52-T109 HydrophobicContact CD1-CG2 4.09Å; I52-T109 HydrophobicContact CG2-CG2 4.03Å; I52-C300 HydrophobicContact CD1-CB 3.4Å; I52-C300 VanDerWaalsContact CD1-CB 3.4Å; I52-C300 HydrophobicContact CG1-CB 4.04Å
53	V	90.4	Very high	87.3	Confident	39 Å²	39	52.8 Å²	52.8	24%	0.236	30%	0.298	C	S	.	.	H	α-helix	trans	-60.7	-41.7	179.1	173.7	0	0	0	0	111.7	K49 I50 Y56 S57 G106 F110	K49-V53 WeakPolarHBondContact O-CG2 3.35Å; K49-V53 PolarHBondContact O-N 3.43Å; I50-V53 PolarHBondContact O-N 3.01Å; V53-Y56 PolarHBondContact O-N 3.2Å; V53-S57 WeakPolarHBondContact O-CB 3.46Å; V53-S57 PolarHBondContact O-N 3.12Å; V53-S57 PolarHBondContact O-OG 3.4Å; V53-G106 WeakPolarHBondContact CG2-O 3.44Å; V53-F110 HydrophobicContact CG2-CB 3.92Å; V53-F110 HydrophobicContact CG2-CD2 4.23Å; V53-F110 HydrophobicContact CG2-CG 4.46Å
54	V	92.2	Very high	88.9	Confident	76 Å²	76	49 Å²	49	46%	0.461	28%	0.283	S	S	.	.	H	α-helix	trans	-62.7	-45.3	176	169.8	0	0	0	0	110.6	I50 T51 I52 S57 I58	I50-V54 HydrophobicContact CG2-CG2 4.33Å; I50-V54 VanDerWaalsContact O-CG2 3.27Å; I50-V54 WeakPolarHBondContact O-CG2 3.24Å; I50-V54 PolarHBondContact O-N 2.86Å; T51-V54 PolarHBondContact O-N 3.35Å; I52-V54 VanDerWaalsContact C-N 3.32Å; I52-V54 PolarHBondContact O-N 3.4Å; V54-S57 PolarHBondContact O-N 3.39Å; V54-I58 HydrophobicContact CG1-CD1 3.92Å; V54-I58 WeakPolarHBondContact O-CG1 3.27Å; V54-I58 PolarHBondContact O-N 3.18Å
55	V	91.2	Very high	89.9	Confident	56 Å²	56	52.5 Å²	52.5	34%	0.339	31%	0.305	S	S	.	.	H	α-helix	trans	-61.8	-47	177	171.8	0	0	0	0	111.1	T51 I52 S57 I58 V59 A304	T51-V55 VanDerWaalsContact O-CG2 3.32Å; T51-V55 WeakPolarHBondContact O-CG2 3.44Å; T51-V55 PolarHBondContact O-N 3.01Å; I52-V55 PolarHBondContact O-N 3.14Å; I52-V55 VanDerWaalsContact O-N 3.16Å; V55-S57 VanDerWaalsContact C-N 3.3Å; V55-S57 PolarHBondContact O-N 3.23Å; V55-I58 PolarHBondContact O-N 3.25Å; V55-V59 HydrophobicContact CG1-CG2 4.32Å; V55-V59 WeakPolarHBondContact O-CB 3.32Å; V55-V59 WeakPolarHBondContact O-CG2 3.29Å; V55-V59 PolarHBondContact O-N 2.93Å; V55-A304 HydrophobicContact CG1-CB 4.04Å
56	Y	92.1	Very high	90.3	Very high	11 Å²	11	50.7 Å²	50.7	4%	0.043	30%	0.296	C	S	.	.	H	α-helix	trans	-60	-41.2	177.2	-77	10.3	0	0	0	111.6	I52 V53 V59 C60 L102 Q105 A304 Y307	I52-Y56 HydrophobicContact CG2-CD1 4.14Å; I52-Y56 HydrophobicContact CG2-CD2 4.3Å; I52-Y56 HydrophobicContact CG2-CE1 3.83Å; I52-Y56 HydrophobicContact CG2-CE2 3.98Å; I52-Y56 HydrophobicContact CG2-CG 4.37Å; I52-Y56 PolarHBondContact O-N 3.4Å; V53-Y56 PolarHBondContact O-N 3.2Å; Y56-V59 PolarHBondContact O-N 3.36Å; Y56-C60 WeakPolarHBondContact O-CB 3.46Å; Y56-C60 PolarHBondContact O-N 2.77Å; Y56-L102 HydrophobicContact CD2-CD2 4.41Å; Y56-L102 HydrophobicContact CG-CD2 4.47Å; Y56-Q105 HydrophobicContact CE2-CB 4.27Å; Y56-A304 HydrophobicContact CD1-CB 4.26Å; Y56-A304 HydrophobicContact CE1-CB 3.69Å; Y56-Y307 HydrophobicContact CE1-CD2 4.1Å
57	S	93.3	Very high	90.7	Very high	59 Å²	59	46 Å²	46	41%	0.413	27%	0.272	S	S	.	.	H	α-helix	trans	-62.8	-44	177.3	-59.8	0	0	0	0	111.9	V53 V54 V55 C60 I61	V53-S57 WeakPolarHBondContact O-CB 3.46Å; V53-S57 PolarHBondContact O-N 3.12Å; V53-S57 PolarHBondContact O-OG 3.4Å; V54-S57 PolarHBondContact O-N 3.39Å; V55-S57 VanDerWaalsContact C-N 3.3Å; V55-S57 PolarHBondContact O-N 3.23Å; S57-C60 PolarHBondContact O-N 3.42Å; S57-I61 VanDerWaalsContact O-CG1 3.28Å; S57-I61 WeakPolarHBondContact O-CG1 3.34Å; S57-I61 PolarHBondContact O-N 3.43Å
58	I	92.5	Very high	91	Very high	99 Å²	99	47.4 Å²	47.4	51%	0.508	28%	0.276	S	S	.	.	H	α-helix	trans	-63.9	-48.5	176.8	-67.7	166.3	0	0	0	110.6	V54 V55 C60 I61 V62	V54-I58 HydrophobicContact CG1-CD1 3.92Å; V54-I58 WeakPolarHBondContact O-CG1 3.27Å; V54-I58 PolarHBondContact O-N 3.18Å; V55-I58 PolarHBondContact O-N 3.25Å; I58-C60 VanDerWaalsContact C-N 3.33Å; I58-C60 PolarHBondContact O-N 3.24Å; I58-I61 PolarHBondContact O-N 3.39Å; I58-V62 HydrophobicContact CG2-CG2 4.27Å; I58-V62 WeakPolarHBondContact O-CB 3.39Å; I58-V62 VanDerWaalsContact O-CG2 3.3Å; I58-V62 WeakPolarHBondContact O-CG2 3.5Å; I58-V62 PolarHBondContact O-N 2.79Å
59	V	92.2	Very high	91.2	Very high	12 Å²	12	45.6 Å²	45.6	7%	0.073	27%	0.269	C	S	.	.	H	α-helix	trans	-60.2	-43.9	179.2	169.8	0	0	0	0	110.9	V55 Y56 G63 L99 L102 Y307 A308	V55-V59 HydrophobicContact CG1-CG2 4.32Å; V55-V59 WeakPolarHBondContact O-CB 3.32Å; V55-V59 WeakPolarHBondContact O-CG2 3.29Å; V55-V59 PolarHBondContact O-N 2.93Å; Y56-V59 PolarHBondContact O-N 3.36Å; V59-G63 WeakPolarHBondContact O-CA 3.49Å; V59-G63 PolarHBondContact O-N 3.05Å; V59-L99 HydrophobicContact CG1-CD2 3.81Å; V59-L102 HydrophobicContact CB-CD1 4.36Å; V59-L102 HydrophobicContact CG1-CD1 3.9Å; V59-Y307 WeakPolarHBondContact CG1-O 3.44Å; V59-A308 HydrophobicContact CG2-CB 4.31Å
60	C	93.9	Very high	91.4	Very high	13 Å²	13	44.4 Å²	44.4	9%	0.088	26%	0.263	C	S	.	.	H	α-helix	trans	-58.9	-54.9	176.2	-178	0	0	0	0	111.3	Y56 S57 I58 G63 L64 L99 L102	Y56-C60 WeakPolarHBondContact O-CB 3.46Å; Y56-C60 PolarHBondContact O-N 2.77Å; S57-C60 PolarHBondContact O-N 3.42Å; I58-C60 VanDerWaalsContact C-N 3.33Å; I58-C60 PolarHBondContact O-N 3.24Å; C60-G63 PolarHBondContact O-N 2.98Å; C60-L64 VanDerWaalsContact O-CB 3.28Å; C60-L64 WeakPolarHBondContact O-CB 3.48Å; C60-L64 WeakPolarHBondContact O-CG 3.38Å; C60-L64 PolarHBondContact O-N 2.93Å; C60-L64 VanDerWaalsContact SG-CD1 3.57Å; C60-L99 PolarHBondContact SG-O 3.19Å; C60-L102 HydrophobicContact CB-CB 4.2Å; C60-L102 HydrophobicContact CB-CD1 3.99Å
61	I	93.1	Very high	91.5	Very high	110 Å²	110	43.1 Å²	43.1	56%	0.564	26%	0.256	S	S	*	.	H	α-helix	trans	-62	-51.2	-177.5	-67.2	166.2	0	0	0	111.2	S57 I58 G63 V65	S57-I61 VanDerWaalsContact O-CG1 3.28Å; S57-I61 WeakPolarHBondContact O-CG1 3.34Å; S57-I61 PolarHBondContact O-N 3.43Å; I58-I61 PolarHBondContact O-N 3.39Å; I61-G63 VanDerWaalsContact C-N 3.34Å; I61-G63 PolarHBondContact O-N 3.15Å; I61-V65 WeakPolarHBondContact O-CB 3.31Å; I61-V65 VanDerWaalsContact O-CG2 3.28Å; I61-V65 WeakPolarHBondContact O-CG2 3.48Å; I61-V65 PolarHBondContact O-N 3.04Å; I61-V65 VanDerWaalsContact O-N 3.07Å
62	V	91.3	Very high	91.5	Very high	72 Å²	72	44.5 Å²	44.5	44%	0.436	25%	0.253	S	S	.	.	H	α-helix	trans	-62	-45.7	-178.4	172.9	0	0	0	0	110.4	I58 G66	I58-V62 HydrophobicContact CG2-CG2 4.27Å; I58-V62 WeakPolarHBondContact O-CB 3.39Å; I58-V62 VanDerWaalsContact O-CG2 3.3Å; I58-V62 WeakPolarHBondContact O-CG2 3.5Å; I58-V62 PolarHBondContact O-N 2.79Å; V62-G66 PolarHBondContact O-N 3.18Å
63	G	91.9	Very high	91.5	Very high	0 Å²	0	43.9 Å²	43.9	0%	0	25%	0.25	C	C	.	.	H	α-helix	trans	-68.3	-43.1	-178	0	0	0	0	0	112.9	V59 C60 I61 G66 N67 L99	V59-G63 WeakPolarHBondContact O-CA 3.49Å; V59-G63 PolarHBondContact O-N 3.05Å; C60-G63 PolarHBondContact O-N 2.98Å; I61-G63 VanDerWaalsContact C-N 3.34Å; I61-G63 PolarHBondContact O-N 3.15Å; G63-G66 PolarHBondContact O-N 3.34Å; G63-N67 VanDerWaalsContact O-CB 3.26Å; G63-N67 WeakPolarHBondContact O-CB 3.4Å; G63-N67 PolarHBondContact O-N 2.99Å; G63-N67 PolarHBondContact O-ND2 3.43Å; G63-L99 VanDerWaalsContact CA-CD1 3.42Å
64	L	93.7	Very high	91.4	Very high	37 Å²	37	42.5 Å²	42.5	19%	0.194	24%	0.24	C	C	.	.	H	α-helix	trans	-65.1	-46.6	178.7	-72.6	177.4	0	0	0	111.2	C60 G66 C68 T96 L99 M100	C60-L64 VanDerWaalsContact O-CB 3.28Å; C60-L64 WeakPolarHBondContact O-CB 3.48Å; C60-L64 WeakPolarHBondContact O-CG 3.38Å; C60-L64 PolarHBondContact O-N 2.93Å; C60-L64 VanDerWaalsContact SG-CD1 3.57Å; L64-G66 PolarHBondContact O-N 3.34Å; L64-C68 WeakPolarHBondContact O-CB 3.44Å; L64-C68 PolarHBondContact O-N 3.33Å; L64-C68 PolarHBondContact O-SG 3.48Å; L64-T96 HydrophobicContact CD2-CG2 3.85Å; L64-L99 HydrophobicContact CD2-CB 3.76Å; L64-L99 HydrophobicContact CG-CB 3.98Å; L64-M100 HydrophobicContact CD1-SD 3.86Å; L64-M100 HydrophobicContact CD2-CG 3.91Å; L64-M100 HydrophobicContact CD2-SD 3.84Å
65	V	91.3	Very high	91.3	Very high	94 Å²	94	43.1 Å²	43.1	57%	0.57	24%	0.244	S	C	*	.	H	α-helix	trans	-61.9	-45.9	177.4	172.9	0	0	0	0	110.6	I61 S69	I61-V65 WeakPolarHBondContact O-CB 3.31Å; I61-V65 VanDerWaalsContact O-CG2 3.28Å; I61-V65 WeakPolarHBondContact O-CG2 3.48Å; I61-V65 PolarHBondContact O-N 3.04Å; I61-V65 VanDerWaalsContact O-N 3.07Å; V65-S69 VanDerWaalsContact O-CB 3.3Å; V65-S69 WeakPolarHBondContact O-CB 3.43Å; V65-S69 PolarHBondContact O-N 3.29Å; V65-S69 VanDerWaalsContact O-N 3.1Å; V65-S69 PolarHBondContact O-OG 3.48Å
66	G	90.4	Very high	91	Very high	16 Å²	16	47.8 Å²	47.8	17%	0.165	26%	0.256	C	S	.	.	H	α-helix	trans	-63.9	-53.5	-179.5	0	0	0	0	0	112.9	V62 G63 L64 S69 V70 P314	V62-G66 PolarHBondContact O-N 3.18Å; G63-G66 PolarHBondContact O-N 3.34Å; L64-G66 PolarHBondContact O-N 3.34Å; G66-S69 WeakPolarHBondContact O-CB 3.42Å; G66-S69 PolarHBondContact O-N 3.48Å; G66-V70 WeakPolarHBondContact O-CG2 3.46Å; G66-V70 PolarHBondContact O-N 2.87Å; G66-P314 VanDerWaalsContact C-CG 3.43Å
67	N	93.6	Very high	90.5	Very high	0 Å²	0	50 Å²	50	0%	0	27%	0.266	C	S	.	.	H	α-helix	trans	-69.2	-39.6	-176	-73.8	-60.8	0	0	0	112.1	G63 S69 V70 M71 A92 T96 S310 P314	G63-N67 VanDerWaalsContact O-CB 3.26Å; G63-N67 WeakPolarHBondContact O-CB 3.4Å; G63-N67 PolarHBondContact O-N 2.99Å; G63-N67 PolarHBondContact O-ND2 3.43Å; N67-S69 VanDerWaalsContact C-N 3.31Å; N67-S69 PolarHBondContact O-N 2.99Å; N67-V70 WeakPolarHBondContact O-CB 3.34Å; N67-V70 PolarHBondContact O-N 3.27Å; N67-M71 WeakPolarHBondContact O-CG 3.45Å; N67-M71 PolarHBondContact O-N 2.87Å; N67-A92 HydrophobicContact CB-CB 4.11Å; N67-A92 WeakPolarHBondContact OD1-CA 3.39Å; N67-T96 WeakPolarHBondContact CB-OG1 3.26Å; N67-S310 PolarHBondContact ND2-O 2.9Å; N67-P314 HydrophobicContact CB-CG 4.38Å; N67-P314 VanDerWaalsContact OD1-CG 3.31Å; N67-P314 WeakPolarHBondContact OD1-CG 3.38Å
68	C	92.6	Very high	89.8	Confident	56 Å²	56	52.5 Å²	52.5	38%	0.378	28%	0.279	S	S	.	.	H	α-helix	trans	-60.6	-40.9	172.3	-72.3	0	0	0	0	111.9	L64 M71 Y72	L64-C68 WeakPolarHBondContact O-CB 3.44Å; L64-C68 PolarHBondContact O-N 3.33Å; L64-C68 PolarHBondContact O-SG 3.48Å; C68-M71 PolarHBondContact O-N 3.25Å; C68-Y72 WeakPolarHBondContact O-CB 3.38Å; C68-Y72 PolarHBondContact O-N 3.27Å
69	S	88.8	Confident	89	Confident	20 Å²	20	57 Å²	57	14%	0.14	30%	0.295	C	S	.	.	H	α-helix	trans	-62.8	-42.8	175.7	-61.9	0	0	0	0	111.9	V65 G66 N67 Y72 V73	V65-S69 VanDerWaalsContact O-CB 3.3Å; V65-S69 WeakPolarHBondContact O-CB 3.43Å; V65-S69 PolarHBondContact O-N 3.29Å; V65-S69 VanDerWaalsContact O-N 3.1Å; V65-S69 PolarHBondContact O-OG 3.48Å; G66-S69 WeakPolarHBondContact O-CB 3.42Å; G66-S69 PolarHBondContact O-N 3.48Å; N67-S69 VanDerWaalsContact C-N 3.31Å; N67-S69 PolarHBondContact O-N 2.99Å; S69-Y72 PolarHBondContact O-N 2.97Å; S69-V73 WeakPolarHBondContact O-CB 3.46Å; S69-V73 VanDerWaalsContact O-CG2 3.3Å; S69-V73 WeakPolarHBondContact O-CG2 3.35Å; S69-V73 PolarHBondContact O-N 2.72Å
70	V	89.7	Confident	88.4	Confident	0 Å²	0	56.8 Å²	56.8	0%	0	29%	0.293	C	S	.	.	H	α-helix	trans	-58.3	-51.4	175.2	170.4	0	0	0	0	110.6	G66 N67 Y72 V73 I74 I88 A92 P314 Y317 F324	G66-V70 WeakPolarHBondContact O-CG2 3.46Å; G66-V70 PolarHBondContact O-N 2.87Å; N67-V70 WeakPolarHBondContact O-CB 3.34Å; N67-V70 PolarHBondContact O-N 3.27Å; V70-Y72 PolarHBondContact O-N 3.43Å; V70-V73 PolarHBondContact O-N 3.4Å; V70-I74 HydrophobicContact CG1-CD1 3.72Å; V70-I74 WeakPolarHBondContact O-CD1 3.46Å; V70-I74 VanDerWaalsContact O-CG1 3.31Å; V70-I74 WeakPolarHBondContact O-CG1 3.43Å; V70-I74 PolarHBondContact O-N 3.34Å; V70-I74 VanDerWaalsContact O-N 3.14Å; V70-I88 HydrophobicContact CG1-CG2 3.55Å; V70-A92 HydrophobicContact CB-CB 4.29Å; V70-A92 HydrophobicContact CG1-CB 4Å; V70-P314 HydrophobicContact CG2-CB 4.01Å; V70-P314 HydrophobicContact CG2-CG 4.27Å; V70-Y317 HydrophobicContact CG2-CD2 4.42Å; V70-F324 HydrophobicContact CB-CE2 4.26Å; V70-F324 HydrophobicContact CB-CZ 4.21Å; V70-F324 HydrophobicContact CG1-CE2 4.28Å; V70-F324 HydrophobicContact CG2-CE1 4.42Å; V70-F324 HydrophobicContact CG2-CE2 3.89Å; V70-F324 HydrophobicContact CG2-CZ 3.46Å; V70-F324 VanDerWaalsContact CG2-CZ 3.46Å
71	M	91.9	Very high	87.8	Confident	36 Å²	36	61 Å²	61	18%	0.177	31%	0.31	C	S	.	.	H	α-helix	trans	-58.7	-47.2	178.5	-68.6	-163.8	-47.5	0	0	111.6	N67 C68 V73 I74 V75 F89 A92 L93	N67-M71 WeakPolarHBondContact O-CG 3.45Å; N67-M71 PolarHBondContact O-N 2.87Å; C68-M71 PolarHBondContact O-N 3.25Å; M71-V73 PolarHBondContact O-N 2.89Å; M71-I74 PolarHBondContact O-N 3.27Å; M71-V75 WeakPolarHBondContact O-CG2 3.38Å; M71-V75 PolarHBondContact O-N 2.97Å; M71-F89 HydrophobicContact CB-CD2 4.06Å; M71-F89 HydrophobicContact CB-CE2 3.72Å; M71-F89 HydrophobicContact CG-CD2 4.02Å; M71-F89 HydrophobicContact CG-CE2 3.86Å; M71-F89 HydrophobicContact CG-CZ 4.44Å; M71-F89 HydrophobicContact SD-CE2 4.22Å; M71-F89 HydrophobicContact SD-CZ 4.22Å; M71-A92 HydrophobicContact CG-CB 3.72Å; M71-L93 HydrophobicContact SD-CB 4.12Å; M71-L93 HydrophobicContact SD-CD1 4.31Å
72	Y	88.6	Confident	87.6	Confident	116 Å²	116	58.6 Å²	58.6	46%	0.455	30%	0.3	S	S	.	.	H	α-helix	trans	-58.7	-49.4	179.8	174.8	-99.9	0	0	0	112.3	C68 S69 V70 I74 V75 R76 F331	C68-Y72 WeakPolarHBondContact O-CB 3.38Å; C68-Y72 PolarHBondContact O-N 3.27Å; S69-Y72 PolarHBondContact O-N 2.97Å; V70-Y72 PolarHBondContact O-N 3.43Å; Y72-I74 VanDerWaalsContact C-N 3.32Å; Y72-I74 PolarHBondContact O-N 3.47Å; Y72-V75 PolarHBondContact O-N 2.98Å; Y72-R76 WeakPolarHBondContact O-CB 3.27Å; Y72-R76 PolarHBondContact O-N 3.44Å; Y72-F331 HydrophobicContact CD1-CD2 4.13Å; Y72-F331 AromaticContact CD1-CE2 3.94Å; Y72-F331 HydrophobicContact CD1-CE2 3.94Å; Y72-F331 AromaticContact CE1-CD2 3.6Å; Y72-F331 HydrophobicContact CE1-CD2 3.6Å; Y72-F331 AromaticContact CE1-CE2 3.51Å; Y72-F331 HydrophobicContact CE1-CE2 3.51Å; Y72-F331 HydrophobicContact CE1-CZ 4.48Å
73	V	87	Confident	87.4	Confident	0 Å²	0	55.5 Å²	55.5	0%	0	28%	0.282	C	S	.	.	H	α-helix	trans	-58.8	-44.1	179.1	167.5	0	0	0	0	110.9	S69 V70 M71 R76 F77 M80 F324 C327	S69-V73 WeakPolarHBondContact O-CB 3.46Å; S69-V73 VanDerWaalsContact O-CG2 3.3Å; S69-V73 WeakPolarHBondContact O-CG2 3.35Å; S69-V73 PolarHBondContact O-N 2.72Å; V70-V73 PolarHBondContact O-N 3.4Å; M71-V73 PolarHBondContact O-N 2.89Å; V73-R76 PolarHBondContact O-N 3.21Å; V73-F77 HydrophobicContact CB-CD2 4.46Å; V73-F77 HydrophobicContact CG1-CD2 3.88Å; V73-F77 HydrophobicContact CG1-CE2 4.32Å; V73-F77 VanDerWaalsContact O-CD2 3.27Å; V73-F77 WeakPolarHBondContact O-CD2 3.46Å; V73-F77 PolarHBondContact O-N 2.85Å; V73-F77 VanDerWaalsContact O-N 3.08Å; V73-M80 HydrophobicContact CG1-CE 4.31Å; V73-M80 HydrophobicContact CG1-CG 4.42Å; V73-F324 HydrophobicContact CB-CE2 4.49Å; V73-F324 HydrophobicContact CG1-CE2 4.33Å; V73-C327 HydrophobicContact CG1-CB 3.81Å
74	I	88.1	Confident	87.1	Confident	9 Å²	9	55.7 Å²	55.7	5%	0.046	28%	0.284	C	S	.	.	H	α-helix	trans	-66.6	-41.6	-178.7	-66.7	164.8	0	0	0	111.5	V70 M71 Y72 N85 I88 F89	V70-I74 HydrophobicContact CG1-CD1 3.72Å; V70-I74 WeakPolarHBondContact O-CD1 3.46Å; V70-I74 VanDerWaalsContact O-CG1 3.31Å; V70-I74 WeakPolarHBondContact O-CG1 3.43Å; V70-I74 PolarHBondContact O-N 3.34Å; V70-I74 VanDerWaalsContact O-N 3.14Å; M71-I74 PolarHBondContact O-N 3.27Å; Y72-I74 VanDerWaalsContact C-N 3.32Å; Y72-I74 PolarHBondContact O-N 3.47Å; I74-N85 HydrophobicContact CD1-CB 4.46Å; I74-N85 HydrophobicContact CG1-CB 4.46Å; I74-I88 HydrophobicContact CD1-CB 4.36Å; I74-I88 HydrophobicContact CD1-CG2 3.96Å; I74-F89 HydrophobicContact CB-CD2 4.39Å; I74-F89 HydrophobicContact CD1-CB 4.11Å; I74-F89 HydrophobicContact CG2-CB 4.38Å; I74-F89 HydrophobicContact CG2-CD2 4.29Å
75	V	89.3	Confident	86.9	Confident	90 Å²	90	54.6 Å²	54.6	55%	0.545	28%	0.278	S	S	.	.	H	α-helix	trans	-66.8	-43.2	178.2	171.8	0	0	0	0	111	M71 Y72 K81 F89	M71-V75 WeakPolarHBondContact O-CG2 3.38Å; M71-V75 PolarHBondContact O-N 2.97Å; Y72-V75 PolarHBondContact O-N 2.98Å; V75-K81 WeakPolarHBondContact O-CE 3.43Å; V75-F89 HydrophobicContact CG2-CD2 4.37Å; V75-F89 HydrophobicContact CG2-CE2 3.67Å; V75-F89 HydrophobicContact CG2-CZ 4.44Å
76	R	85.8	Confident	86.9	Confident	153 Å²	153	50.9 Å²	50.9	58%	0.577	26%	0.255	S	S	*	.	H	α-helix	trans	-74	-36.7	-172.3	-178.5	60.4	-174.3	85.6	-4.9	114.1	Y72 V73	Y72-R76 WeakPolarHBondContact O-CB 3.27Å; Y72-R76 PolarHBondContact O-N 3.44Å; V73-R76 PolarHBondContact O-N 3.21Å
77	F	82.3	Confident	87	Confident	58 Å²	58	50.8 Å²	50.8	25%	0.254	25%	0.249	S	C	.	.			trans	-103.4	111.9	-175.1	-65	-71.7	0	0	0	111.2	V73 K79 M80 C327	V73-F77 HydrophobicContact CB-CD2 4.46Å; V73-F77 HydrophobicContact CG1-CD2 3.88Å; V73-F77 HydrophobicContact CG1-CE2 4.32Å; V73-F77 VanDerWaalsContact O-CD2 3.27Å; V73-F77 WeakPolarHBondContact O-CD2 3.46Å; V73-F77 PolarHBondContact O-N 2.85Å; V73-F77 VanDerWaalsContact O-N 3.08Å; F77-K79 PolarHBondContact O-N 3.31Å; F77-M80 HydrophobicContact CB-CB 4.24Å; F77-M80 HydrophobicContact CB-CG 3.74Å; F77-M80 WeakPolarHBondContact O-CA 3.49Å; F77-M80 WeakPolarHBondContact O-CB 3.35Å; F77-M80 PolarHBondContact O-N 2.84Å; F77-C327 HydrophobicContact CD2-CB 4.18Å; F77-C327 HydrophobicContact CE2-CB 4.13Å
78	T	78	Confident	86.9	Confident	112 Å²	112	51.4 Å²	51.4	69%	0.687	25%	0.252	S	S	*	.	G	3₁₀ helix	trans	-56.6	-35.4	177.8	37.4	0	0	0	0	113.3	M80 K81	T78-M80 PolarHBondContact O-N 3.27Å; T78-M80 VanDerWaalsContact O-N 3.16Å; T78-K81 WeakPolarHBondContact O-CB 3.07Å; T78-K81 PolarHBondContact O-N 3.46Å; T78-K81 VanDerWaalsContact O-N 3.09Å
79	K	76.3	Confident	86.9	Confident	192 Å²	192	51.8 Å²	51.8	84%	0.835	25%	0.248	S	C	*	.	G	3₁₀ helix	trans	-61	-20.8	174.4	-65.5	-170.6	178.6	-174.2	0	113.5	F77	F77-K79 PolarHBondContact O-N 3.31Å
80	M	78.4	Confident	87.2	Confident	9 Å²	9	51.1 Å²	51.1	4%	0.044	24%	0.243	C	C	.	.	G	3₁₀ helix	trans	-89.7	-1.7	179.1	-61.2	-63.9	-76.4	0	0	112.8	V73 F77 T78 T82 N85 N323 F324	V73-M80 HydrophobicContact CG1-CE 4.31Å; V73-M80 HydrophobicContact CG1-CG 4.42Å; F77-M80 HydrophobicContact CB-CB 4.24Å; F77-M80 HydrophobicContact CB-CG 3.74Å; F77-M80 WeakPolarHBondContact O-CA 3.49Å; F77-M80 WeakPolarHBondContact O-CB 3.35Å; F77-M80 PolarHBondContact O-N 2.84Å; T78-M80 PolarHBondContact O-N 3.27Å; T78-M80 VanDerWaalsContact O-N 3.16Å; M80-T82 PolarHBondContact O-N 3.33Å; M80-N85 WeakPolarHBondContact O-CB 3.3Å; M80-N85 PolarHBondContact O-ND2 3.42Å; M80-N323 HydrophobicContact SD-CB 4.43Å; M80-F324 HydrophobicContact CE-CD2 4.06Å
81	K	82.8	Confident	87.3	Confident	102 Å²	102	51.1 Å²	51.1	44%	0.443	24%	0.243	S	C	.	.			trans	-83.3	51.6	-178.9	-61.9	-178.1	-179.5	177.9	0	112.6	V75 T78 P162	V75-K81 WeakPolarHBondContact O-CE 3.43Å; T78-K81 WeakPolarHBondContact O-CB 3.07Å; T78-K81 PolarHBondContact O-N 3.46Å; T78-K81 VanDerWaalsContact O-N 3.09Å; K81-P162 VanDerWaalsContact O-CG 3.26Å; K81-P162 WeakPolarHBondContact O-CG 3.21Å
82	T	87.7	Confident	87.4	Confident	59 Å²	59	49.4 Å²	49.4	36%	0.362	23%	0.234	S	C	.	.			trans	-89.4	162.2	176.4	68.6	0	0	0	0	111.1	M80 T84 N85 I86	M80-T82 PolarHBondContact O-N 3.33Å; T82-T84 VanDerWaalsContact C-N 3.34Å; T82-T84 PolarHBondContact O-N 3.34Å; T82-N85 PolarHBondContact O-N 3.27Å; T82-N85 WeakPolarHBondContact OG1-CB 3.47Å; T82-N85 PolarHBondContact OG1-N 2.71Å; T82-N85 PolarHBondContact OG1-ND2 2.87Å; T82-I86 WeakPolarHBondContact O-CG1 3.23Å; T82-I86 PolarHBondContact O-N 2.69Å
83	A	86.9	Confident	87.7	Confident	6 Å²	6	46.6 Å²	46.6	5%	0.05	23%	0.227	C	C	.	.	H	α-helix	trans	-56.4	-45.2	177	0	0	0	0	0	112.5	N85 I86 Y87 R160 A165	A83-N85 VanDerWaalsContact C-N 3.35Å; A83-N85 PolarHBondContact O-N 3.47Å; A83-I86 WeakPolarHBondContact O-CB 3.48Å; A83-I86 PolarHBondContact O-N 3.5Å; A83-Y87 WeakPolarHBondContact O-CD2 3.46Å; A83-Y87 PolarHBondContact O-N 3.36Å; A83-R160 HydrophobicContact CB-CB 4.28Å; A83-R160 WeakPolarHBondContact CB-O 3.35Å; A83-A165 HydrophobicContact CB-CB 3.96Å
84	T	86.5	Confident	88.1	Confident	5 Å²	5	46.7 Å²	46.7	3%	0.031	23%	0.228	C	C	.	.	H	α-helix	trans	-62.5	-41.5	177	-50.1	0	0	0	0	112.2	T82 I86 Y87 I88 M142 D145 R160	T82-T84 VanDerWaalsContact C-N 3.34Å; T82-T84 PolarHBondContact O-N 3.34Å; T84-I86 PolarHBondContact O-N 2.69Å; T84-Y87 WeakPolarHBondContact O-CB 3.46Å; T84-Y87 PolarHBondContact O-N 2.91Å; T84-Y87 VanDerWaalsContact O-N 3.13Å; T84-I88 HydrophobicContact CG2-CD1 4.32Å; T84-I88 WeakPolarHBondContact O-CG1 3.25Å; T84-I88 PolarHBondContact O-N 3.36Å; T84-M142 HydrophobicContact CG2-CE 4.43Å; T84-D145 PolarHBondContact OG1-OD2 3.31Å; T84-R160 PolarHBondContact OG1-NH2 3.02Å
85	N	88.4	Confident	88.5	Confident	13 Å²	13	46.3 Å²	46.3	7%	0.07	23%	0.225	C	C	.	.	H	α-helix	trans	-70.4	-22.8	-179.8	-68.4	-6.6	0	0	0	112.5	I74 M80 T82 A83 I88 F89	I74-N85 HydrophobicContact CD1-CB 4.46Å; I74-N85 HydrophobicContact CG1-CB 4.46Å; M80-N85 WeakPolarHBondContact O-CB 3.3Å; M80-N85 PolarHBondContact O-ND2 3.42Å; T82-N85 PolarHBondContact O-N 3.27Å; T82-N85 WeakPolarHBondContact OG1-CB 3.47Å; T82-N85 PolarHBondContact OG1-N 2.71Å; T82-N85 PolarHBondContact OG1-ND2 2.87Å; A83-N85 VanDerWaalsContact C-N 3.35Å; A83-N85 PolarHBondContact O-N 3.47Å; N85-I88 PolarHBondContact O-N 2.95Å; N85-F89 WeakPolarHBondContact O-CB 3.49Å; N85-F89 PolarHBondContact O-N 3.18Å
86	I	92.6	Very high	88.7	Confident	17 Å²	17	43 Å²	43	9%	0.087	21%	0.205	C	C	.	.	H	α-helix	trans	-69.6	-35.8	170.8	-75.2	163	0	0	0	111.5	T82 A83 T84 N90 P162 A165 K166 N169	T82-I86 WeakPolarHBondContact O-CG1 3.23Å; T82-I86 PolarHBondContact O-N 2.69Å; A83-I86 WeakPolarHBondContact O-CB 3.48Å; A83-I86 PolarHBondContact O-N 3.5Å; T84-I86 PolarHBondContact O-N 2.69Å; I86-N90 PolarHBondContact O-N 3.47Å; I86-N90 VanDerWaalsContact O-N 3.11Å; I86-P162 VanDerWaalsContact CD1-CA 3.49Å; I86-P162 HydrophobicContact CD1-CB 3.48Å; I86-P162 VanDerWaalsContact CD1-CB 3.48Å; I86-P162 WeakPolarHBondContact CD1-O 3.2Å; I86-A165 HydrophobicContact CB-CB 4.06Å; I86-A165 HydrophobicContact CD1-CB 4.44Å; I86-A165 HydrophobicContact CG2-CB 3.8Å; I86-K166 HydrophobicContact CD1-CG 4.22Å; I86-K166 HydrophobicContact CG2-CG 4.03Å; I86-N169 WeakPolarHBondContact CG2-ND2 3.34Å; I86-N169 PolarHBondContact O-ND2 2.94Å; I86-N169 VanDerWaalsContact O-ND2 3.1Å
87	Y	91.8	Very high	89.2	Confident	14 Å²	14	39.1 Å²	39.1	6%	0.055	20%	0.196	C	C	.	.	H	α-helix	trans	-67.4	-42.3	170.2	-63.1	-55.8	0	0	0	111.6	A83 T84 F89 N90 L91 T138 M141 M142 D145 A165 V168 N169	A83-Y87 WeakPolarHBondContact O-CD2 3.46Å; A83-Y87 PolarHBondContact O-N 3.36Å; T84-Y87 WeakPolarHBondContact O-CB 3.46Å; T84-Y87 PolarHBondContact O-N 2.91Å; T84-Y87 VanDerWaalsContact O-N 3.13Å; Y87-F89 VanDerWaalsContact C-N 3.29Å; Y87-F89 PolarHBondContact O-N 3.47Å; Y87-N90 WeakPolarHBondContact O-CB 3.18Å; Y87-N90 PolarHBondContact O-N 3.07Å; Y87-N90 VanDerWaalsContact O-N 3.11Å; Y87-L91 PolarHBondContact O-N 3.09Å; Y87-T138 WeakPolarHBondContact O-CG2 3.37Å; Y87-M141 HydrophobicContact CD1-CG 4.25Å; Y87-M141 HydrophobicContact CE1-CB 4.4Å; Y87-M141 HydrophobicContact CE1-CG 3.58Å; Y87-M141 HydrophobicContact CE2-CG 4.25Å; Y87-M142 HydrophobicContact CD2-CG 4.34Å; Y87-M142 HydrophobicContact CG-CG 4.12Å; Y87-D145 HydrophobicContact CE2-CB 4.14Å; Y87-A165 HydrophobicContact CE1-CB 4.32Å; Y87-A165 HydrophobicContact CE2-CB 4.21Å; Y87-V168 HydrophobicContact CE1-CB 4.11Å; Y87-V168 HydrophobicContact CE1-CG1 3.85Å; Y87-N169 WeakPolarHBondContact CD1-OD1 3.48Å
88	I	90.8	Very high	89.8	Confident	12 Å²	12	36.4 Å²	36.4	6%	0.062	18%	0.184	C	C	.	.	H	α-helix	trans	-60.1	-41.1	175.6	-67.2	172.5	0	0	0	111.2	V70 I74 T84 N85 N90 L91 A92 M142 Y317	V70-I88 HydrophobicContact CG1-CG2 3.55Å; I74-I88 HydrophobicContact CD1-CB 4.36Å; I74-I88 HydrophobicContact CD1-CG2 3.96Å; T84-I88 HydrophobicContact CG2-CD1 4.32Å; T84-I88 WeakPolarHBondContact O-CG1 3.25Å; T84-I88 PolarHBondContact O-N 3.36Å; N85-I88 PolarHBondContact O-N 2.95Å; I88-N90 VanDerWaalsContact C-N 3.33Å; I88-N90 PolarHBondContact O-N 3.24Å; I88-L91 PolarHBondContact O-N 3.47Å; I88-A92 WeakPolarHBondContact O-CB 3.44Å; I88-A92 PolarHBondContact O-N 3.25Å; I88-M142 HydrophobicContact CD1-CE 4.32Å; I88-M142 HydrophobicContact CG1-CE 3.66Å; I88-M142 HydrophobicContact CG1-SD 4.42Å; I88-Y317 HydrophobicContact CB-CE2 4.49Å; I88-Y317 HydrophobicContact CD1-CD1 4.26Å; I88-Y317 HydrophobicContact CD1-CE1 4.1Å; I88-Y317 HydrophobicContact CG1-CE1 4.1Å; I88-Y317 HydrophobicContact CG1-CE2 4.38Å; I88-Y317 HydrophobicContact CG2-CD2 3.89Å; I88-Y317 HydrophobicContact CG2-CE2 3.57Å
89	F	93.3	Very high	90.6	Very high	64 Å²	64	31.1 Å²	31.1	28%	0.281	15%	0.152	S	C	.	.	H	α-helix	trans	-60.9	-42.7	174.5	-177.8	-84.4	0	0	0	111.7	M71 I74 V75 N85 Y87 A92 L93	M71-F89 HydrophobicContact CB-CD2 4.06Å; M71-F89 HydrophobicContact CB-CE2 3.72Å; M71-F89 HydrophobicContact CG-CD2 4.02Å; M71-F89 HydrophobicContact CG-CE2 3.86Å; M71-F89 HydrophobicContact CG-CZ 4.44Å; M71-F89 HydrophobicContact SD-CE2 4.22Å; M71-F89 HydrophobicContact SD-CZ 4.22Å; I74-F89 HydrophobicContact CB-CD2 4.39Å; I74-F89 HydrophobicContact CD1-CB 4.11Å; I74-F89 HydrophobicContact CG2-CB 4.38Å; I74-F89 HydrophobicContact CG2-CD2 4.29Å; V75-F89 HydrophobicContact CG2-CD2 4.37Å; V75-F89 HydrophobicContact CG2-CE2 3.67Å; V75-F89 HydrophobicContact CG2-CZ 4.44Å; N85-F89 WeakPolarHBondContact O-CB 3.49Å; N85-F89 PolarHBondContact O-N 3.18Å; Y87-F89 VanDerWaalsContact C-N 3.29Å; Y87-F89 PolarHBondContact O-N 3.47Å; F89-A92 PolarHBondContact O-N 3.31Å; F89-L93 WeakPolarHBondContact O-CB 3.23Å; F89-L93 PolarHBondContact O-N 3.19Å
90	N	94.7	Very high	91.4	Very high	6 Å²	6	27.3 Å²	27.3	3%	0.032	14%	0.138	C	C	.	.	H	α-helix	trans	-61.2	-44.4	177.4	-164.3	63.2	0	0	0	112.2	I86 Y87 I88 L93 A94 T138 N169 W173	I86-N90 PolarHBondContact O-N 3.47Å; I86-N90 VanDerWaalsContact O-N 3.11Å; Y87-N90 WeakPolarHBondContact O-CB 3.18Å; Y87-N90 PolarHBondContact O-N 3.07Å; Y87-N90 VanDerWaalsContact O-N 3.11Å; I88-N90 VanDerWaalsContact C-N 3.33Å; I88-N90 PolarHBondContact O-N 3.24Å; N90-L93 PolarHBondContact O-N 3.48Å; N90-A94 PolarHBondContact O-N 3.38Å; N90-T138 HydrophobicContact CB-CG2 4.41Å; N90-T138 PolarHBondContact ND2-OG1 3.4Å; N90-N169 WeakPolarHBondContact CB-ND2 3.34Å; N90-W173 PolarHBondContact OD1-NE1 3.03Å
91	L	92.3	Very high	92.1	Very high	0 Å²	0	27.1 Å²	27.1	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-62.7	-47.3	176.7	-170.4	67.2	0	0	0	111	Y87 I88 L93 A94 D95 S135 T138 L139 N313 Y317	Y87-L91 PolarHBondContact O-N 3.09Å; I88-L91 PolarHBondContact O-N 3.47Å; L91-L93 VanDerWaalsContact C-N 3.27Å; L91-L93 PolarHBondContact O-N 3.19Å; L91-A94 PolarHBondContact O-N 3.27Å; L91-D95 WeakPolarHBondContact O-CB 3.47Å; L91-D95 PolarHBondContact O-N 3Å; L91-S135 VanDerWaalsContact CD1-CA 3.5Å; L91-S135 WeakPolarHBondContact CD1-OG 3.39Å; L91-T138 HydrophobicContact CB-CG2 4.16Å; L91-L139 HydrophobicContact CD2-CD2 4.23Å; L91-N313 HydrophobicContact CD2-CB 4.29Å; L91-Y317 WeakPolarHBondContact CD2-OH 3.32Å
92	A	94.1	Very high	92.5	Very high	0 Å²	0	22.3 Å²	22.3	0%	0	12%	0.117	C	C	.	.	H	α-helix	trans	-61.2	-35.3	177.8	0	0	0	0	0	112.7	N67 V70 M71 I88 F89 T96	N67-A92 HydrophobicContact CB-CB 4.11Å; N67-A92 WeakPolarHBondContact OD1-CA 3.39Å; V70-A92 HydrophobicContact CB-CB 4.29Å; V70-A92 HydrophobicContact CG1-CB 4Å; M71-A92 HydrophobicContact CG-CB 3.72Å; I88-A92 WeakPolarHBondContact O-CB 3.44Å; I88-A92 PolarHBondContact O-N 3.25Å; F89-A92 PolarHBondContact O-N 3.31Å; A92-T96 VanDerWaalsContact O-CB 3.3Å; A92-T96 WeakPolarHBondContact O-CB 3.42Å; A92-T96 PolarHBondContact O-N 3.1Å; A92-T96 PolarHBondContact O-OG1 3.21Å
93	L	95.6	Very high	92.8	Very high	58 Å²	58	22.8 Å²	22.8	30%	0.304	12%	0.121	S	C	.	.	H	α-helix	trans	-65.8	-50.6	174	177.4	63.3	0	0	0	111.3	M71 F89 N90 L91 D95 T96 L97 W173	M71-L93 HydrophobicContact SD-CB 4.12Å; M71-L93 HydrophobicContact SD-CD1 4.31Å; F89-L93 WeakPolarHBondContact O-CB 3.23Å; F89-L93 PolarHBondContact O-N 3.19Å; N90-L93 PolarHBondContact O-N 3.48Å; L91-L93 VanDerWaalsContact C-N 3.27Å; L91-L93 PolarHBondContact O-N 3.19Å; L93-D95 VanDerWaalsContact C-N 3.33Å; L93-D95 PolarHBondContact O-N 3.02Å; L93-T96 PolarHBondContact O-N 3.21Å; L93-L97 HydrophobicContact CD1-CD1 4.46Å; L93-L97 HydrophobicContact CG-CD1 4.41Å; L93-L97 WeakPolarHBondContact O-CG 3.37Å; L93-L97 PolarHBondContact O-N 3.26Å; L93-W173 HydrophobicContact CD2-CZ2 4.22Å; L93-W173 HydrophobicContact CG-CZ2 4.48Å
94	A	95.3	Very high	93	Very high	2 Å²	2	25.9 Å²	25.9	2%	0.017	13%	0.133	C	C	.	.	H	α-helix	trans	-60	-42.9	178.4	0	0	0	0	0	112	N90 L91 L97 C98 N131 T134	N90-A94 PolarHBondContact O-N 3.38Å; L91-A94 PolarHBondContact O-N 3.27Å; A94-L97 PolarHBondContact O-N 2.85Å; A94-C98 PolarHBondContact O-N 3.35Å; A94-C98 VanDerWaalsContact O-N 3.16Å; A94-N131 PolarHBondContact O-ND2 2.87Å; A94-T134 VanDerWaalsContact CB-OG1 3.25Å; A94-T134 WeakPolarHBondContact CB-OG1 3.27Å
95	D	94.9	Very high	93.1	Very high	0 Å²	0	27 Å²	27	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-65.2	-43.3	176.6	-73.8	-23.4	0	0	0	111.6	L91 L93 L97 C98 L99 N131 S135 S310 N313	L91-D95 WeakPolarHBondContact O-CB 3.47Å; L91-D95 PolarHBondContact O-N 3Å; L93-D95 VanDerWaalsContact C-N 3.33Å; L93-D95 PolarHBondContact O-N 3.02Å; D95-L97 VanDerWaalsContact C-N 3.32Å; D95-L97 PolarHBondContact O-N 3.43Å; D95-C98 PolarHBondContact O-N 3.29Å; D95-L99 WeakPolarHBondContact O-CB 3.37Å; D95-L99 WeakPolarHBondContact O-CD1 3.49Å; D95-L99 WeakPolarHBondContact O-CG 3.44Å; D95-L99 PolarHBondContact O-N 3.03Å; D95-N131 WeakPolarHBondContact CA-ND2 3.49Å; D95-N131 PolarHBondContact N-ND2 3.06Å; D95-N131 PolarHBondContact OD1-ND2 2.79Å; D95-N131 VanDerWaalsContact OD1-ND2 3.13Å; D95-S135 PolarHBondContact OD1-OG 3.11Å; D95-S310 VanDerWaalsContact CG-CB 3.47Å; D95-S310 WeakPolarHBondContact OD1-CB 3.48Å; D95-S310 PolarHBondContact OD1-OG 3.06Å; D95-N313 PolarHBondContact OD2-ND2 2.89Å
96	T	95.3	Very high	93.1	Very high	20 Å²	20	26.6 Å²	26.6	12%	0.123	14%	0.137	C	C	.	.	H	α-helix	trans	-60	-43.6	177.2	-58.6	0	0	0	0	111.2	L64 N67 A92 L93 L99 M100	L64-T96 HydrophobicContact CD2-CG2 3.85Å; N67-T96 WeakPolarHBondContact CB-OG1 3.26Å; A92-T96 VanDerWaalsContact O-CB 3.3Å; A92-T96 WeakPolarHBondContact O-CB 3.42Å; A92-T96 PolarHBondContact O-N 3.1Å; A92-T96 PolarHBondContact O-OG1 3.21Å; L93-T96 PolarHBondContact O-N 3.21Å; T96-L99 PolarHBondContact O-N 2.97Å; T96-M100 VanDerWaalsContact O-CG 3.24Å; T96-M100 WeakPolarHBondContact O-CG 3.38Å; T96-M100 PolarHBondContact O-N 3.33Å
97	L	95.2	Very high	93	Very high	73 Å²	73	28.2 Å²	28.2	38%	0.382	15%	0.148	S	C	.	.	H	α-helix	trans	-61.7	-45.4	178.6	-68.7	170.6	0	0	0	111.7	L93 A94 D95 M100 I127 W173	L93-L97 HydrophobicContact CD1-CD1 4.46Å; L93-L97 HydrophobicContact CG-CD1 4.41Å; L93-L97 WeakPolarHBondContact O-CG 3.37Å; L93-L97 PolarHBondContact O-N 3.26Å; A94-L97 PolarHBondContact O-N 2.85Å; D95-L97 VanDerWaalsContact C-N 3.32Å; D95-L97 PolarHBondContact O-N 3.43Å; L97-M100 PolarHBondContact O-N 3.29Å; L97-I127 HydrophobicContact CB-CG2 4.11Å; L97-I127 WeakPolarHBondContact O-CG2 3.22Å; L97-W173 HydrophobicContact CD1-CH2 4.01Å
98	C	94.4	Very high	92.7	Very high	1 Å²	1	29 Å²	29	1%	0.007	15%	0.153	C	C	.	.	H	α-helix	trans	-61.8	-46.8	175.6	-174.5	0	0	0	0	112.4	A94 D95 M100 T101 N131	A94-C98 PolarHBondContact O-N 3.35Å; A94-C98 VanDerWaalsContact O-N 3.16Å; D95-C98 PolarHBondContact O-N 3.29Å; C98-M100 PolarHBondContact O-N 2.94Å; C98-M100 VanDerWaalsContact O-N 3.14Å; C98-T101 PolarHBondContact O-N 3.35Å; C98-T101 PolarHBondContact O-OG1 2.89Å; C98-N131 HydrophobicContact CB-CB 3.63Å; C98-N131 VanDerWaalsContact CB-CG 3.47Å; C98-N131 WeakPolarHBondContact CB-ND2 3.35Å
99	L	94.8	Very high	92.4	Very high	0 Å²	0	29.7 Å²	29.7	0%	0	16%	0.158	C	C	.	.	H	α-helix	trans	-65.7	-23.4	-177.8	-65.8	165.9	0	0	0	113	V59 C60 G63 L64 D95 T96 T101 L102	V59-L99 HydrophobicContact CG1-CD2 3.81Å; C60-L99 PolarHBondContact SG-O 3.19Å; G63-L99 VanDerWaalsContact CA-CD1 3.42Å; L64-L99 HydrophobicContact CD2-CB 3.76Å; L64-L99 HydrophobicContact CG-CB 3.98Å; D95-L99 WeakPolarHBondContact O-CB 3.37Å; D95-L99 WeakPolarHBondContact O-CD1 3.49Å; D95-L99 WeakPolarHBondContact O-CG 3.44Å; D95-L99 PolarHBondContact O-N 3.03Å; T96-L99 PolarHBondContact O-N 2.97Å; L99-T101 VanDerWaalsContact C-N 3.28Å; L99-L102 HydrophobicContact CD2-CD1 3.61Å; L99-L102 PolarHBondContact O-N 3.4Å
100	M	94.2	Very high	92.1	Very high	112 Å²	112	31.1 Å²	31.1	55%	0.552	16%	0.164	S	C	*	.	T	Hydrogen-bonded Turn	trans	-70.8	-20.2	172	-68.6	-69.4	-70.9	0	0	113	L64 T96 L97 C98 P103	L64-M100 HydrophobicContact CD1-SD 3.86Å; L64-M100 HydrophobicContact CD2-CG 3.91Å; L64-M100 HydrophobicContact CD2-SD 3.84Å; T96-M100 VanDerWaalsContact O-CG 3.24Å; T96-M100 WeakPolarHBondContact O-CG 3.38Å; T96-M100 PolarHBondContact O-N 3.33Å; L97-M100 PolarHBondContact O-N 3.29Å; C98-M100 PolarHBondContact O-N 2.94Å; C98-M100 VanDerWaalsContact O-N 3.14Å; M100-P103 WeakPolarHBondContact O-CD 3.25Å
101	T	92.8	Very high	91.6	Very high	6 Å²	6	34.3 Å²	34.3	4%	0.037	18%	0.181	C	C	.	.	T	Hydrogen-bonded Turn	trans	-82.1	-24	176.5	71.3	0	0	0	0	112.2	C98 L99 P103 F104 Q105 I127 D128	C98-T101 PolarHBondContact O-N 3.35Å; C98-T101 PolarHBondContact O-OG1 2.89Å; L99-T101 VanDerWaalsContact C-N 3.28Å; T101-P103 VanDerWaalsContact C-CD 3.47Å; T101-F104 WeakPolarHBondContact O-CB 3.23Å; T101-F104 PolarHBondContact O-N 2.88Å; T101-Q105 PolarHBondContact O-N 3.44Å; T101-Q105 VanDerWaalsContact O-N 3.11Å; T101-I127 HydrophobicContact CG2-CB 3.91Å; T101-I127 HydrophobicContact CG2-CD1 3.94Å; T101-I127 HydrophobicContact CG2-CG2 3.61Å; T101-D128 PolarHBondContact OG1-OD1 3.4Å; T101-D128 VanDerWaalsContact OG1-OD1 3.04Å
102	L	91.9	Very high	91	Very high	1 Å²	1	36.5 Å²	36.5	1%	0.005	20%	0.203	C	C	.	.	H	α-helix	trans	-54.3	-38.2	-175.2	-71.8	-176.4	0	0	0	116.3	Y56 V59 C60 L99 F104 Q105 G106 Y307	Y56-L102 HydrophobicContact CD2-CD2 4.41Å; Y56-L102 HydrophobicContact CG-CD2 4.47Å; V59-L102 HydrophobicContact CB-CD1 4.36Å; V59-L102 HydrophobicContact CG1-CD1 3.9Å; C60-L102 HydrophobicContact CB-CB 4.2Å; C60-L102 HydrophobicContact CB-CD1 3.99Å; L99-L102 HydrophobicContact CD2-CD1 3.61Å; L99-L102 PolarHBondContact O-N 3.4Å; L102-F104 VanDerWaalsContact C-N 3.27Å; L102-F104 PolarHBondContact O-N 3.2Å; L102-Q105 PolarHBondContact O-N 3.43Å; L102-G106 PolarHBondContact O-N 2.8Å; L102-Y307 HydrophobicContact CD2-CD1 3.87Å; L102-Y307 HydrophobicContact CD2-CD2 3.47Å; L102-Y307 VanDerWaalsContact CD2-CD2 3.47Å; L102-Y307 HydrophobicContact CD2-CE1 4.04Å; L102-Y307 HydrophobicContact CD2-CE2 3.62Å; L102-Y307 HydrophobicContact CD2-CG 3.6Å
103	P	92.9	Very high	90.5	Very high	68 Å²	68	40.6 Å²	40.6	44%	0.442	22%	0.221	S	C	.	.	H	α-helix	trans	-62.2	-35.6	175.7	-24.6	35.8	0	0	0	112.9	M100 T101 T107	M100-P103 WeakPolarHBondContact O-CD 3.25Å; T101-P103 VanDerWaalsContact C-CD 3.47Å; P103-T107 PolarHBondContact O-N 2.89Å; P103-T107 PolarHBondContact O-OG1 2.8Å
104	F	91.3	Very high	90.1	Very high	71 Å²	71	37.9 Å²	37.9	31%	0.311	21%	0.207	S	C	.	.	H	α-helix	trans	-71.2	-46.1	177	-53.9	-77.6	0	0	0	110.5	T101 L102 G106 T107 D108 W114 F116 L120	T101-F104 WeakPolarHBondContact O-CB 3.23Å; T101-F104 PolarHBondContact O-N 2.88Å; L102-F104 VanDerWaalsContact C-N 3.27Å; L102-F104 PolarHBondContact O-N 3.2Å; F104-G106 VanDerWaalsContact C-N 3.31Å; F104-G106 PolarHBondContact O-N 2.93Å; F104-T107 WeakPolarHBondContact O-CB 3.28Å; F104-T107 PolarHBondContact O-N 2.94Å; F104-T107 VanDerWaalsContact O-N 3.14Å; F104-D108 PolarHBondContact O-N 3.01Å; F104-W114 HydrophobicContact CB-CH2 3.8Å; F104-W114 HydrophobicContact CB-CZ3 4.18Å; F104-F116 HydrophobicContact CB-CD2 4.15Å; F104-F116 HydrophobicContact CB-CE2 3.86Å; F104-F116 HydrophobicContact CB-CZ 4.39Å; F104-F116 AromaticContact CD1-CD1 3.92Å; F104-F116 HydrophobicContact CD1-CD1 3.92Å; F104-F116 HydrophobicContact CD1-CD2 4.03Å; F104-F116 AromaticContact CD1-CE1 3.75Å; F104-F116 HydrophobicContact CD1-CE1 3.75Å; F104-F116 AromaticContact CD1-CE2 3.87Å; F104-F116 HydrophobicContact CD1-CE2 3.87Å; F104-F116 HydrophobicContact CD1-CG 4.05Å; F104-F116 AromaticContact CD1-CZ 3.72Å; F104-F116 HydrophobicContact CD1-CZ 3.72Å; F104-F116 HydrophobicContact CE1-CD1 4.33Å; F104-F116 HydrophobicContact CE1-CE1 4.24Å; F104-F116 HydrophobicContact CG-CE2 4.38Å; F104-L120 HydrophobicContact CD1-CD2 3.48Å; F104-L120 VanDerWaalsContact CD1-CD2 3.48Å; F104-L120 HydrophobicContact CE1-CD2 3.59Å; F104-L120 HydrophobicContact CG-CD2 3.98Å; F104-L120 HydrophobicContact CZ-CD2 4.15Å
105	Q	88.6	Confident	89.8	Confident	29 Å²	29	40.6 Å²	40.6	14%	0.136	23%	0.225	C	C	.	.	H	α-helix	trans	-60.2	-39.4	175.1	-62.1	-67.7	12.7	0	0	112.4	Y56 T101 L102 D108 T109 D128	Y56-Q105 HydrophobicContact CE2-CB 4.27Å; T101-Q105 PolarHBondContact O-N 3.44Å; T101-Q105 VanDerWaalsContact O-N 3.11Å; L102-Q105 PolarHBondContact O-N 3.43Å; Q105-D108 PolarHBondContact O-N 3.25Å; Q105-T109 PolarHBondContact O-N 3.32Å; Q105-T109 PolarHBondContact O-OG1 2.77Å; Q105-D128 PolarHBondContact NE2-OD2 3.13Å
106	G	88.8	Confident	89.6	Confident	5 Å²	5	44.1 Å²	44.1	5%	0.052	24%	0.24	C	C	.	.	H	α-helix	trans	-66.5	-37.4	175.5	0	0	0	0	0	112.6	V53 L102 F104 F110	V53-G106 WeakPolarHBondContact CG2-O 3.44Å; L102-G106 PolarHBondContact O-N 2.8Å; F104-G106 VanDerWaalsContact C-N 3.31Å; F104-G106 PolarHBondContact O-N 2.93Å; G106-F110 WeakPolarHBondContact O-CB 3.36Å; G106-F110 PolarHBondContact O-N 3.27Å
107	T	89.4	Confident	89.3	Confident	51 Å²	51	44.9 Å²	44.9	31%	0.313	25%	0.251	S	S	.	.	H	α-helix	trans	-67.2	-43.3	175.7	-55.9	0	0	0	0	111.2	P103 F104 F110 L111 P115 F116	P103-T107 PolarHBondContact O-N 2.89Å; P103-T107 PolarHBondContact O-OG1 2.8Å; F104-T107 WeakPolarHBondContact O-CB 3.28Å; F104-T107 PolarHBondContact O-N 2.94Å; F104-T107 VanDerWaalsContact O-N 3.14Å; T107-F110 PolarHBondContact O-N 3.36Å; T107-L111 HydrophobicContact CG2-CD1 3.65Å; T107-L111 HydrophobicContact CG2-CG 4.12Å; T107-L111 WeakPolarHBondContact O-CB 3.38Å; T107-L111 WeakPolarHBondContact O-CG 3.39Å; T107-L111 PolarHBondContact O-N 3.1Å; T107-P115 HydrophobicContact CG2-CG 4.26Å; T107-F116 HydrophobicContact CG2-CE2 4.09Å; T107-F116 HydrophobicContact CG2-CZ 3.69Å
108	D	85.8	Confident	89.1	Confident	31 Å²	31	43.7 Å²	43.7	17%	0.166	25%	0.245	C	C	.	.	H	α-helix	trans	-56.7	-50.7	173.8	177.1	75.1	0	0	0	111.7	F104 Q105 F110 L111 G112 F113 W114	F104-D108 PolarHBondContact O-N 3.01Å; Q105-D108 PolarHBondContact O-N 3.25Å; D108-F110 VanDerWaalsContact C-N 3.29Å; D108-F110 PolarHBondContact O-N 2.85Å; D108-L111 PolarHBondContact O-N 3.47Å; D108-G112 WeakPolarHBondContact O-CA 3.37Å; D108-G112 PolarHBondContact O-N 2.84Å; D108-F113 PolarHBondContact O-N 2.93Å; D108-F113 VanDerWaalsContact OD1-C 3.24Å; D108-W114 HydrophobicContact CB-CE3 3.78Å; D108-W114 HydrophobicContact CB-CZ3 4.22Å; D108-W114 WeakPolarHBondContact OD1-CA 3.17Å; D108-W114 WeakPolarHBondContact OD1-CB 3.49Å; D108-W114 PolarHBondContact OD1-N 2.98Å
109	T	84.2	Confident	89	Confident	25 Å²	25	48.9 Å²	48.9	15%	0.153	28%	0.277	C	S	.	.	H	α-helix	trans	-61.5	-35.8	176.5	-58.5	0	0	0	0	112.8	I52 Q105	I52-T109 HydrophobicContact CB-CG2 4.43Å; I52-T109 HydrophobicContact CD1-CG2 4.09Å; I52-T109 HydrophobicContact CG2-CG2 4.03Å; Q105-T109 PolarHBondContact O-N 3.32Å; Q105-T109 PolarHBondContact O-OG1 2.77Å
110	F	87	Confident	88.8	Confident	94 Å²	94	51.2 Å²	51.2	41%	0.412	29%	0.289	S	S	.	.	H	α-helix	trans	-72	-49.8	-179.7	-174.6	-102.9	0	0	0	112	L46 K49 I50 V53 G106 T107 D108 G112	L46-F110 HydrophobicContact CD1-CE2 4.28Å; K49-F110 HydrophobicContact CB-CD2 4.38Å; K49-F110 PolarHBondContact NZ-O 3.02Å; I50-F110 HydrophobicContact CG1-CE2 4.26Å; V53-F110 HydrophobicContact CG2-CB 3.92Å; V53-F110 HydrophobicContact CG2-CD2 4.23Å; V53-F110 HydrophobicContact CG2-CG 4.46Å; G106-F110 WeakPolarHBondContact O-CB 3.36Å; G106-F110 PolarHBondContact O-N 3.27Å; T107-F110 PolarHBondContact O-N 3.36Å; D108-F110 VanDerWaalsContact C-N 3.29Å; D108-F110 PolarHBondContact O-N 2.85Å; F110-G112 VanDerWaalsContact C-N 3.34Å
111	L	85.8	Confident	88.7	Confident	73 Å²	73	45.9 Å²	45.9	38%	0.382	26%	0.263	S	S	.	.	H	α-helix	trans	-73.3	-27.7	-179	-66.4	179.6	0	0	0	112.3	T107 D108 F113 P115	T107-L111 HydrophobicContact CG2-CD1 3.65Å; T107-L111 HydrophobicContact CG2-CG 4.12Å; T107-L111 WeakPolarHBondContact O-CB 3.38Å; T107-L111 WeakPolarHBondContact O-CG 3.39Å; T107-L111 PolarHBondContact O-N 3.1Å; D108-L111 PolarHBondContact O-N 3.47Å; L111-F113 VanDerWaalsContact C-N 3.28Å; L111-F113 HydrophobicContact CB-CD1 3.85Å; L111-F113 HydrophobicContact CB-CE1 3.75Å; L111-F113 HydrophobicContact CB-CG 4.44Å; L111-F113 HydrophobicContact CB-CZ 4.25Å; L111-F113 HydrophobicContact CD1-CE1 4.35Å; L111-F113 HydrophobicContact CD1-CE2 4.37Å; L111-F113 HydrophobicContact CD1-CZ 4.02Å; L111-F113 HydrophobicContact CG-CE1 4.44Å; L111-P115 HydrophobicContact CD1-CB 4.4Å; L111-P115 HydrophobicContact CD1-CG 3.92Å
112	G	79.6	Confident	88.7	Confident	46 Å²	46	48.2 Å²	48.2	47%	0.474	27%	0.273	S	S	.	.	T	Hydrogen-bonded Turn	trans	74.8	18.1	-171.4	0	0	0	0	0	113.3	D108 F110	D108-G112 WeakPolarHBondContact O-CA 3.37Å; D108-G112 PolarHBondContact O-N 2.84Å; F110-G112 VanDerWaalsContact C-N 3.34Å
113	F	83.9	Confident	88.7	Confident	87 Å²	87	51.6 Å²	51.6	38%	0.382	29%	0.29	S	S	.	.	S	Bend	trans	-160.1	160.8	173.4	69	-91.1	0	0	0	109.8	D108 L111 P115 I196	D108-F113 PolarHBondContact O-N 2.93Å; D108-F113 VanDerWaalsContact OD1-C 3.24Å; L111-F113 VanDerWaalsContact C-N 3.28Å; L111-F113 HydrophobicContact CB-CD1 3.85Å; L111-F113 HydrophobicContact CB-CE1 3.75Å; L111-F113 HydrophobicContact CB-CG 4.44Å; L111-F113 HydrophobicContact CB-CZ 4.25Å; L111-F113 HydrophobicContact CD1-CE1 4.35Å; L111-F113 HydrophobicContact CD1-CE2 4.37Å; L111-F113 HydrophobicContact CD1-CZ 4.02Å; L111-F113 HydrophobicContact CG-CE1 4.44Å; F113-P115 HydrophobicContact CD2-CB 4.47Å; F113-P115 HydrophobicContact CE2-CB 3.94Å; F113-P115 WeakPolarHBondContact O-CD 3.25Å; F113-I196 CarbonylContact C-O 3.22Å; F113-I196 WeakPolarHBondContact CA-O 3.45Å; F113-I196 WeakPolarHBondContact CB-O 3.26Å
114	W	87.3	Confident	88.6	Confident	1 Å²	1	48.5 Å²	48.5	0%	0.004	27%	0.27	C	S	.	.			trans	-93.6	104.2	-178	-177.6	-94.7	0	0	0	112.8	F104 D108 F116 G117 L120 C121 A124 A189 I196 C198	F104-W114 HydrophobicContact CB-CH2 3.8Å; F104-W114 HydrophobicContact CB-CZ3 4.18Å; D108-W114 HydrophobicContact CB-CE3 3.78Å; D108-W114 HydrophobicContact CB-CZ3 4.22Å; D108-W114 WeakPolarHBondContact OD1-CA 3.17Å; D108-W114 WeakPolarHBondContact OD1-CB 3.49Å; D108-W114 PolarHBondContact OD1-N 2.98Å; W114-F116 HydrophobicContact CD2-CD2 4Å; W114-F116 AromaticContact CE2-CD2 3.81Å; W114-F116 HydrophobicContact CE3-CD2 4.16Å; W114-F116 AromaticContact CH2-CD2 3.95Å; W114-F116 HydrophobicContact CH2-CD2 3.95Å; W114-F116 HydrophobicContact CZ2-CB 3.87Å; W114-F116 AromaticContact CZ2-CD2 3.78Å; W114-F116 HydrophobicContact CZ2-CD2 3.78Å; W114-F116 HydrophobicContact CZ2-CG 4.26Å; W114-F116 HydrophobicContact CZ3-CD2 4.14Å; W114-G117 PolarHBondContact NE1-O 3.42Å; W114-L120 HydrophobicContact CZ2-CB 4.03Å; W114-L120 HydrophobicContact CZ2-CD2 4.15Å; W114-L120 HydrophobicContact CZ2-CG 3.98Å; W114-C121 HydrophobicContact CD2-CB 4.5Å; W114-C121 HydrophobicContact CZ2-CB 4.22Å; W114-A124 HydrophobicContact CH2-CB 3.97Å; W114-A189 HydrophobicContact CG-CB 4.3Å; W114-I196 HydrophobicContact CB-CG2 4.25Å; W114-I196 PolarHBondContact N-O 2.92Å; W114-I196 VanDerWaalsContact O-CG2 3.26Å; W114-I196 WeakPolarHBondContact O-CG2 3.44Å; W114-C198 HydrophobicContact CB-CB 3.89Å; W114-C198 HydrophobicContact CD2-CB 3.56Å; W114-C198 HydrophobicContact CE3-CB 3.66Å; W114-C198 HydrophobicContact CG-CB 3.66Å; W114-C198 HydrophobicContact CZ3-CB 4.41Å
115	P	88.5	Confident	88.6	Confident	59 Å²	59	45.8 Å²	45.8	38%	0.383	26%	0.258	S	S	.	.	T	Hydrogen-bonded Turn	trans	-85.5	-8.3	-175.3	35.3	-38.8	0	0	0	114.3	T107 L111 F113 G117	T107-P115 HydrophobicContact CG2-CG 4.26Å; L111-P115 HydrophobicContact CD1-CB 4.4Å; L111-P115 HydrophobicContact CD1-CG 3.92Å; F113-P115 HydrophobicContact CD2-CB 4.47Å; F113-P115 HydrophobicContact CE2-CB 3.94Å; F113-P115 WeakPolarHBondContact O-CD 3.25Å; P115-G117 PolarHBondContact O-N 3.47Å
116	F	89.4	Confident	88.8	Confident	74 Å²	74	44.5 Å²	44.5	33%	0.325	25%	0.253	S	S	.	.	T	Hydrogen-bonded Turn	trans	-92.4	3.3	-165.2	-50.4	-75.1	0	0	0	114.7	F104 T107 W114 L120	F104-F116 HydrophobicContact CB-CD2 4.15Å; F104-F116 HydrophobicContact CB-CE2 3.86Å; F104-F116 HydrophobicContact CB-CZ 4.39Å; F104-F116 AromaticContact CD1-CD1 3.92Å; F104-F116 HydrophobicContact CD1-CD1 3.92Å; F104-F116 HydrophobicContact CD1-CD2 4.03Å; F104-F116 AromaticContact CD1-CE1 3.75Å; F104-F116 HydrophobicContact CD1-CE1 3.75Å; F104-F116 AromaticContact CD1-CE2 3.87Å; F104-F116 HydrophobicContact CD1-CE2 3.87Å; F104-F116 HydrophobicContact CD1-CG 4.05Å; F104-F116 AromaticContact CD1-CZ 3.72Å; F104-F116 HydrophobicContact CD1-CZ 3.72Å; F104-F116 HydrophobicContact CE1-CD1 4.33Å; F104-F116 HydrophobicContact CE1-CE1 4.24Å; F104-F116 HydrophobicContact CG-CE2 4.38Å; T107-F116 HydrophobicContact CG2-CE2 4.09Å; T107-F116 HydrophobicContact CG2-CZ 3.69Å; W114-F116 HydrophobicContact CD2-CD2 4Å; W114-F116 AromaticContact CE2-CD2 3.81Å; W114-F116 HydrophobicContact CE3-CD2 4.16Å; W114-F116 AromaticContact CH2-CD2 3.95Å; W114-F116 HydrophobicContact CH2-CD2 3.95Å; W114-F116 HydrophobicContact CZ2-CB 3.87Å; W114-F116 AromaticContact CZ2-CD2 3.78Å; W114-F116 HydrophobicContact CZ2-CD2 3.78Å; W114-F116 HydrophobicContact CZ2-CG 4.26Å; W114-F116 HydrophobicContact CZ3-CD2 4.14Å; F116-L120 HydrophobicContact CB-CB 4.02Å; F116-L120 HydrophobicContact CB-CD2 3.42Å; F116-L120 VanDerWaalsContact CB-CD2 3.42Å; F116-L120 HydrophobicContact CB-CG 4.27Å; F116-L120 HydrophobicContact CD1-CD2 4.24Å; F116-L120 HydrophobicContact CD2-CD2 4.39Å; F116-L120 HydrophobicContact CG-CD2 3.78Å
117	G	90.3	Very high	89.1	Confident	35 Å²	35	46.2 Å²	46.2	36%	0.361	26%	0.26	S	S	.	.	H	α-helix	trans	76	171.8	179	0	0	0	0	0	114.9	W114 P115 V119 L120 C121	W114-G117 PolarHBondContact NE1-O 3.42Å; P115-G117 PolarHBondContact O-N 3.47Å; G117-V119 PolarHBondContact O-N 3.02Å; G117-L120 PolarHBondContact O-N 2.76Å; G117-C121 PolarHBondContact O-N 2.88Å
118	N	89.9	Confident	89.1	Confident	48 Å²	48	45.1 Å²	45.1	26%	0.257	25%	0.252	S	S	.	.	H	α-helix	trans	-65.4	-36.5	-168.8	-164.3	20.9	0	0	0	114	C121 K122 S188 A189	N118-C121 PolarHBondContact O-N 2.89Å; N118-K122 WeakPolarHBondContact O-CG 3.43Å; N118-K122 PolarHBondContact O-N 2.92Å; N118-S188 WeakPolarHBondContact OD1-CA 3.47Å; N118-A189 PolarHBondContact OD1-N 3.4Å; N118-A189 VanDerWaalsContact OD1-N 3.08Å
119	V	92.1	Very high	89.4	Confident	111 Å²	111	45.7 Å²	45.7	67%	0.673	25%	0.253	S	S	*	.	H	α-helix	trans	-63.3	-47.3	-178.9	176.6	0	0	0	0	111	G117 C121 K122 I123	G117-V119 PolarHBondContact O-N 3.02Å; V119-C121 VanDerWaalsContact C-N 3.33Å; V119-K122 PolarHBondContact O-N 2.69Å; V119-I123 HydrophobicContact CG1-CD1 3.93Å; V119-I123 VanDerWaalsContact O-CG1 3.31Å; V119-I123 WeakPolarHBondContact O-CG1 3.47Å; V119-I123 PolarHBondContact O-N 2.88Å; V119-I123 VanDerWaalsContact O-N 3.13Å
120	L	91.8	Very high	89.9	Confident	49 Å²	49	46.5 Å²	46.5	26%	0.257	25%	0.253	S	S	.	.	H	α-helix	trans	-70	-33.7	180	-165.1	67.1	0	0	0	111.5	F104 W114 F116 G117 I123 A124	F104-L120 HydrophobicContact CD1-CD2 3.48Å; F104-L120 VanDerWaalsContact CD1-CD2 3.48Å; F104-L120 HydrophobicContact CE1-CD2 3.59Å; F104-L120 HydrophobicContact CG-CD2 3.98Å; F104-L120 HydrophobicContact CZ-CD2 4.15Å; W114-L120 HydrophobicContact CZ2-CB 4.03Å; W114-L120 HydrophobicContact CZ2-CD2 4.15Å; W114-L120 HydrophobicContact CZ2-CG 3.98Å; F116-L120 HydrophobicContact CB-CB 4.02Å; F116-L120 HydrophobicContact CB-CD2 3.42Å; F116-L120 VanDerWaalsContact CB-CD2 3.42Å; F116-L120 HydrophobicContact CB-CG 4.27Å; F116-L120 HydrophobicContact CD1-CD2 4.24Å; F116-L120 HydrophobicContact CD2-CD2 4.39Å; F116-L120 HydrophobicContact CG-CD2 3.78Å; G117-L120 PolarHBondContact O-N 2.76Å; L120-I123 PolarHBondContact O-N 3.38Å; L120-A124 VanDerWaalsContact O-CB 3.32Å; L120-A124 WeakPolarHBondContact O-CB 3.34Å; L120-A124 PolarHBondContact O-N 2.91Å
121	C	91.6	Very high	90.2	Very high	0 Å²	0	42.3 Å²	42.3	0%	0	24%	0.235	C	C	.	.	H	α-helix	trans	-58.8	-51.9	173.8	174.3	0	0	0	0	111.6	W114 G117 N118 V119 I123 A124 I125 A189 C198	W114-C121 HydrophobicContact CD2-CB 4.5Å; W114-C121 HydrophobicContact CZ2-CB 4.22Å; G117-C121 PolarHBondContact O-N 2.88Å; N118-C121 PolarHBondContact O-N 2.89Å; V119-C121 VanDerWaalsContact C-N 3.33Å; C121-I123 VanDerWaalsContact C-N 3.27Å; C121-I123 PolarHBondContact O-N 3.47Å; C121-A124 PolarHBondContact O-N 3.37Å; C121-I125 WeakPolarHBondContact O-CB 3.24Å; C121-I125 WeakPolarHBondContact O-CG1 3.34Å; C121-I125 PolarHBondContact O-N 3Å; C121-A189 HydrophobicContact CB-CB 3.66Å; C121-C198 WeakPolarHBondContact CA-SG 3.45Å; C121-C198 HydrophobicContact CB-CB 3.87Å; C121-C198 WeakPolarHBondContact CB-SG 3.22Å; C121-C198 WeakPolarHBondContact SG-CA 3.25Å; C121-C198 WeakPolarHBondContact SG-CB 3.47Å; C121-C198 CovalentContact SG-SG 2.03Å; C121-C198 PolarHBondContact SG-SG 3.29Å
122	K	92.6	Very high	90.4	Very high	55 Å²	55	39.6 Å²	39.6	24%	0.239	22%	0.221	C	C	.	.	H	α-helix	trans	-56.8	-41.1	176.8	-73.3	178.4	178.8	-68.3	0	112.4	N118 V119 S126 M184 V185 G187	N118-K122 WeakPolarHBondContact O-CG 3.43Å; N118-K122 PolarHBondContact O-N 2.92Å; V119-K122 PolarHBondContact O-N 2.69Å; K122-S126 VanDerWaalsContact O-CB 3.26Å; K122-S126 WeakPolarHBondContact O-CB 3.39Å; K122-S126 PolarHBondContact O-N 2.86Å; K122-M184 HydrophobicContact CB-CG 4.27Å; K122-M184 WeakPolarHBondContact CG-O 3.36Å; K122-V185 PolarHBondContact NZ-O 2.89Å; K122-G187 WeakPolarHBondContact CE-O 3.38Å; K122-G187 WeakPolarHBondContact CG-O 3.4Å; K122-G187 PolarHBondContact NZ-O 3.08Å
123	I	92.7	Very high	91	Very high	72 Å²	72	37.4 Å²	37.4	37%	0.369	20%	0.198	S	C	.	.	H	α-helix	trans	-67.3	-47.4	177.6	-68.6	168.6	0	0	0	110.9	V119 L120 C121 S126 I127	V119-I123 HydrophobicContact CG1-CD1 3.93Å; V119-I123 VanDerWaalsContact O-CG1 3.31Å; V119-I123 WeakPolarHBondContact O-CG1 3.47Å; V119-I123 PolarHBondContact O-N 2.88Å; V119-I123 VanDerWaalsContact O-N 3.13Å; L120-I123 PolarHBondContact O-N 3.38Å; C121-I123 VanDerWaalsContact C-N 3.27Å; C121-I123 PolarHBondContact O-N 3.47Å; I123-S126 PolarHBondContact O-N 2.78Å; I123-I127 HydrophobicContact CG2-CD1 3.67Å; I123-I127 HydrophobicContact CG2-CG1 4.34Å; I123-I127 WeakPolarHBondContact O-CB 3.46Å; I123-I127 VanDerWaalsContact O-CG1 3.31Å; I123-I127 WeakPolarHBondContact O-CG1 3.37Å; I123-I127 PolarHBondContact O-N 3.03Å
124	A	91	Very high	91.5	Very high	3 Å²	3	33.3 Å²	33.3	3%	0.025	18%	0.18	C	C	.	.	H	α-helix	trans	-61	-51.3	-179.6	0	0	0	0	0	111.2	W114 L120 C121 S126 I127 D128	W114-A124 HydrophobicContact CH2-CB 3.97Å; L120-A124 VanDerWaalsContact O-CB 3.32Å; L120-A124 WeakPolarHBondContact O-CB 3.34Å; L120-A124 PolarHBondContact O-N 2.91Å; C121-A124 PolarHBondContact O-N 3.37Å; A124-S126 VanDerWaalsContact C-N 3.3Å; A124-S126 PolarHBondContact O-N 2.92Å; A124-I127 PolarHBondContact O-N 3.11Å; A124-D128 PolarHBondContact O-N 3.22Å
125	I	90.7	Very high	91.7	Very high	13 Å²	13	33.2 Å²	33.2	7%	0.067	18%	0.18	C	C	.	.	H	α-helix	trans	-55.1	-47.2	174.8	-71.5	174.8	0	0	0	110.6	C121 I127 D128 Y129 A183 I200	C121-I125 WeakPolarHBondContact O-CB 3.24Å; C121-I125 WeakPolarHBondContact O-CG1 3.34Å; C121-I125 PolarHBondContact O-N 3Å; I125-I127 PolarHBondContact O-N 3.27Å; I125-D128 PolarHBondContact O-N 3.32Å; I125-Y129 HydrophobicContact CG2-CD2 4.18Å; I125-Y129 HydrophobicContact CG2-CE2 4.36Å; I125-Y129 VanDerWaalsContact O-CD2 3.28Å; I125-Y129 WeakPolarHBondContact O-CD2 3.18Å; I125-Y129 PolarHBondContact O-N 3.02Å; I125-Y129 VanDerWaalsContact O-N 3.08Å; I125-A183 HydrophobicContact CG2-CB 4.17Å; I125-I200 HydrophobicContact CD1-CG1 4.32Å; I125-I200 HydrophobicContact CG2-CD1 4.04Å; I125-I200 HydrophobicContact CG2-CG1 3.87Å
126	S	93.1	Very high	91.9	Very high	2 Å²	2	30.4 Å²	30.4	1%	0.014	16%	0.162	C	C	.	.	H	α-helix	trans	-62.6	-44.6	-179.6	-169	0	0	0	0	112.1	K122 I123 A124 D128 Y129 Y130 G180 M184	K122-S126 VanDerWaalsContact O-CB 3.26Å; K122-S126 WeakPolarHBondContact O-CB 3.39Å; K122-S126 PolarHBondContact O-N 2.86Å; I123-S126 PolarHBondContact O-N 2.78Å; A124-S126 VanDerWaalsContact C-N 3.3Å; A124-S126 PolarHBondContact O-N 2.92Å; S126-D128 VanDerWaalsContact C-N 3.34Å; S126-D128 PolarHBondContact O-N 3.34Å; S126-Y129 PolarHBondContact O-N 3.37Å; S126-Y130 WeakPolarHBondContact O-CB 3.29Å; S126-Y130 VanDerWaalsContact O-CD2 3.22Å; S126-Y130 WeakPolarHBondContact O-CD2 3.3Å; S126-Y130 PolarHBondContact O-N 3.12Å; S126-Y130 WeakPolarHBondContact OG-CD2 3.48Å; S126-Y130 WeakPolarHBondContact OG-CE2 3.18Å; S126-G180 PolarHBondContact OG-O 3.42Å; S126-G180 VanDerWaalsContact OG-O 3.04Å; S126-M184 WeakPolarHBondContact OG-CE 3.3Å
127	I	93.7	Very high	92.1	Very high	42 Å²	42	28.3 Å²	28.3	22%	0.215	15%	0.152	C	C	.	.	H	α-helix	trans	-61.1	-43	178.6	-72.4	170.7	0	0	0	111	L97 T101 I123 A124 I125 Y129 Y130 N131	L97-I127 HydrophobicContact CB-CG2 4.11Å; L97-I127 WeakPolarHBondContact O-CG2 3.22Å; T101-I127 HydrophobicContact CG2-CB 3.91Å; T101-I127 HydrophobicContact CG2-CD1 3.94Å; T101-I127 HydrophobicContact CG2-CG2 3.61Å; I123-I127 HydrophobicContact CG2-CD1 3.67Å; I123-I127 HydrophobicContact CG2-CG1 4.34Å; I123-I127 WeakPolarHBondContact O-CB 3.46Å; I123-I127 VanDerWaalsContact O-CG1 3.31Å; I123-I127 WeakPolarHBondContact O-CG1 3.37Å; I123-I127 PolarHBondContact O-N 3.03Å; A124-I127 PolarHBondContact O-N 3.11Å; I125-I127 PolarHBondContact O-N 3.27Å; I127-Y129 VanDerWaalsContact C-N 3.33Å; I127-Y129 PolarHBondContact O-N 3.06Å; I127-Y130 PolarHBondContact O-N 3.35Å; I127-N131 WeakPolarHBondContact O-CB 3.18Å; I127-N131 PolarHBondContact O-N 3.2Å
128	D	91.1	Very high	92.2	Very high	27 Å²	27	26.6 Å²	26.6	14%	0.144	14%	0.135	C	C	.	.	H	α-helix	trans	-63.1	-42.1	179.6	-67.5	-12.5	0	0	0	110.7	T101 Q105 A124 I125 S126 N131 M132 Y307	T101-D128 PolarHBondContact OG1-OD1 3.4Å; T101-D128 VanDerWaalsContact OG1-OD1 3.04Å; Q105-D128 PolarHBondContact NE2-OD2 3.13Å; A124-D128 PolarHBondContact O-N 3.22Å; I125-D128 PolarHBondContact O-N 3.32Å; S126-D128 VanDerWaalsContact C-N 3.34Å; S126-D128 PolarHBondContact O-N 3.34Å; D128-N131 PolarHBondContact O-N 3.4Å; D128-M132 WeakPolarHBondContact O-CB 3.3Å; D128-M132 PolarHBondContact O-N 3.09Å; D128-Y307 PolarHBondContact OD2-OH 3.44Å
129	Y	91.5	Very high	92.1	Very high	44 Å²	44	24.7 Å²	24.7	17%	0.173	13%	0.125	C	C	.	.	H	α-helix	trans	-65.7	-44.5	173.9	-88	-105.7	0	0	0	112.5	I125 S126 I127 N131 M132 F133 A183 I200 F213 V217	I125-Y129 HydrophobicContact CG2-CD2 4.18Å; I125-Y129 HydrophobicContact CG2-CE2 4.36Å; I125-Y129 VanDerWaalsContact O-CD2 3.28Å; I125-Y129 WeakPolarHBondContact O-CD2 3.18Å; I125-Y129 PolarHBondContact O-N 3.02Å; I125-Y129 VanDerWaalsContact O-N 3.08Å; S126-Y129 PolarHBondContact O-N 3.37Å; I127-Y129 VanDerWaalsContact C-N 3.33Å; I127-Y129 PolarHBondContact O-N 3.06Å; Y129-N131 VanDerWaalsContact C-N 3.31Å; Y129-N131 PolarHBondContact O-N 3.33Å; Y129-M132 HydrophobicContact CD1-CE 3.99Å; Y129-M132 HydrophobicContact CE1-CE 4.04Å; Y129-M132 PolarHBondContact O-N 3.4Å; Y129-F133 HydrophobicContact CD1-CE2 4.03Å; Y129-F133 VanDerWaalsContact O-CD2 3.29Å; Y129-F133 WeakPolarHBondContact O-CD2 3.27Å; Y129-F133 PolarHBondContact O-N 3.16Å; Y129-A183 HydrophobicContact CD1-CB 3.83Å; Y129-A183 HydrophobicContact CD2-CB 3.98Å; Y129-A183 HydrophobicContact CE1-CB 4.36Å; Y129-A183 HydrophobicContact CE2-CB 4.48Å; Y129-A183 HydrophobicContact CG-CB 3.64Å; Y129-I200 HydrophobicContact CD2-CD1 4.38Å; Y129-I200 HydrophobicContact CE1-CD1 4.31Å; Y129-I200 HydrophobicContact CE2-CD1 3.43Å; Y129-I200 VanDerWaalsContact CE2-CD1 3.43Å; Y129-I200 WeakPolarHBondContact OH-CD1 3.28Å; Y129-F213 HydrophobicContact CE1-CE1 4.18Å; Y129-F213 AromaticContact CE1-CZ 3.56Å; Y129-F213 HydrophobicContact CE1-CZ 3.56Å; Y129-F213 AromaticContact CZ-CZ 3.78Å; Y129-F213 WeakPolarHBondContact OH-CE1 3.21Å; Y129-F213 WeakPolarHBondContact OH-CZ 3.47Å; Y129-V217 HydrophobicContact CE1-CG2 4.04Å
130	Y	94.2	Very high	92.1	Very high	41 Å²	41	20.1 Å²	20.1	16%	0.161	10%	0.097	C	C	.	.	H	α-helix	trans	-58.9	-44.9	175.1	-92.3	-71	0	0	0	110.9	S126 I127 T134 W173 A176 S177	S126-Y130 WeakPolarHBondContact O-CB 3.29Å; S126-Y130 VanDerWaalsContact O-CD2 3.22Å; S126-Y130 WeakPolarHBondContact O-CD2 3.3Å; S126-Y130 PolarHBondContact O-N 3.12Å; S126-Y130 WeakPolarHBondContact OG-CD2 3.48Å; S126-Y130 WeakPolarHBondContact OG-CE2 3.18Å; I127-Y130 PolarHBondContact O-N 3.35Å; Y130-T134 HydrophobicContact CD1-CG2 4.33Å; Y130-T134 WeakPolarHBondContact O-CB 3.37Å; Y130-T134 WeakPolarHBondContact O-CG2 3.13Å; Y130-T134 PolarHBondContact O-N 3.05Å; Y130-T134 PolarHBondContact O-OG1 3.45Å; Y130-W173 AromaticContact CD1-CE3 3.82Å; Y130-W173 HydrophobicContact CD1-CE3 3.82Å; Y130-W173 AromaticContact CD1-CZ3 3.8Å; Y130-W173 HydrophobicContact CD1-CZ3 3.8Å; Y130-W173 HydrophobicContact CE1-CE3 4.1Å; Y130-W173 HydrophobicContact CE1-CZ3 4.42Å; Y130-W173 HydrophobicContact CG-CZ3 4.26Å; Y130-A176 HydrophobicContact CD1-CB 3.92Å; Y130-A176 HydrophobicContact CE1-CB 4.21Å; Y130-S177 WeakPolarHBondContact CE1-OG 3.3Å; Y130-S177 WeakPolarHBondContact OH-CA 3.41Å; Y130-S177 VanDerWaalsContact OH-CB 3.23Å; Y130-S177 WeakPolarHBondContact OH-CB 3.34Å; Y130-S177 PolarHBondContact OH-OG 2.93Å
131	N	92.9	Very high	92.1	Very high	6 Å²	6	20.6 Å²	20.6	3%	0.032	10%	0.099	C	C	.	.	H	α-helix	trans	-59.6	-51.2	176.4	178.5	-89.6	0	0	0	111.1	A94 D95 C98 I127 D128 Y129 F133 T134 S135	A94-N131 PolarHBondContact O-ND2 2.87Å; D95-N131 WeakPolarHBondContact CA-ND2 3.49Å; D95-N131 PolarHBondContact N-ND2 3.06Å; D95-N131 PolarHBondContact OD1-ND2 2.79Å; D95-N131 VanDerWaalsContact OD1-ND2 3.13Å; C98-N131 HydrophobicContact CB-CB 3.63Å; C98-N131 VanDerWaalsContact CB-CG 3.47Å; C98-N131 WeakPolarHBondContact CB-ND2 3.35Å; I127-N131 WeakPolarHBondContact O-CB 3.18Å; I127-N131 PolarHBondContact O-N 3.2Å; D128-N131 PolarHBondContact O-N 3.4Å; Y129-N131 VanDerWaalsContact C-N 3.31Å; Y129-N131 PolarHBondContact O-N 3.33Å; N131-F133 PolarHBondContact O-N 3.09Å; N131-T134 PolarHBondContact O-N 3.39Å; N131-T134 PolarHBondContact O-OG1 3.21Å; N131-S135 PolarHBondContact ND2-OG 3.47Å; N131-S135 WeakPolarHBondContact O-CB 3.48Å; N131-S135 PolarHBondContact O-N 3.04Å; N131-S135 PolarHBondContact O-OG 3.49Å
132	M	90.5	Very high	91.9	Very high	17 Å²	17	21.7 Å²	21.7	8%	0.084	10%	0.104	C	C	.	.	H	α-helix	trans	-52.8	-50.5	179.8	178.4	174.4	70.1	0	0	112.3	D128 Y129 T136 V217 W274	D128-M132 WeakPolarHBondContact O-CB 3.3Å; D128-M132 PolarHBondContact O-N 3.09Å; Y129-M132 HydrophobicContact CD1-CE 3.99Å; Y129-M132 HydrophobicContact CE1-CE 4.04Å; Y129-M132 PolarHBondContact O-N 3.4Å; M132-T136 VanDerWaalsContact O-CB 3.31Å; M132-T136 WeakPolarHBondContact O-CB 3.5Å; M132-T136 PolarHBondContact O-N 2.77Å; M132-T136 PolarHBondContact O-OG1 3.21Å; M132-V217 HydrophobicContact CE-CG1 3.51Å; M132-V217 HydrophobicContact SD-CG1 4.03Å; M132-W274 HydrophobicContact CB-CH2 3.79Å; M132-W274 HydrophobicContact CB-CZ3 4.13Å; M132-W274 HydrophobicContact CG-CH2 3.76Å; M132-W274 HydrophobicContact CG-CZ3 3.63Å; M132-W274 HydrophobicContact SD-CZ3 4Å
133	F	93.1	Very high	91.7	Very high	0 Å²	0	19.3 Å²	19.3	0%	0	9%	0.094	C	C	.	.	H	α-helix	trans	-75.8	-46.8	-178.3	-76.1	-73.6	0	0	0	113.1	Y129 N131 S135 T136 F137 A176 F179 F220	Y129-F133 HydrophobicContact CD1-CE2 4.03Å; Y129-F133 VanDerWaalsContact O-CD2 3.29Å; Y129-F133 WeakPolarHBondContact O-CD2 3.27Å; Y129-F133 PolarHBondContact O-N 3.16Å; N131-F133 PolarHBondContact O-N 3.09Å; F133-S135 PolarHBondContact O-N 2.89Å; F133-T136 PolarHBondContact O-N 2.92Å; F133-F137 HydrophobicContact CB-CD2 4.34Å; F133-F137 HydrophobicContact CB-CE2 3.98Å; F133-F137 HydrophobicContact CD1-CE1 4.41Å; F133-F137 AromaticContact CD1-CE2 3.92Å; F133-F137 HydrophobicContact CD1-CE2 3.92Å; F133-F137 AromaticContact CD1-CZ 3.66Å; F133-F137 HydrophobicContact CD1-CZ 3.66Å; F133-F137 HydrophobicContact CE1-CZ 4.43Å; F133-F137 HydrophobicContact CG-CE2 4.39Å; F133-F137 WeakPolarHBondContact O-CB 3.19Å; F133-F137 VanDerWaalsContact O-CD2 3.24Å; F133-F137 WeakPolarHBondContact O-CD2 3.15Å; F133-F137 WeakPolarHBondContact O-CG 3.25Å; F133-F137 PolarHBondContact O-N 3.26Å; F133-A176 HydrophobicContact CB-CB 3.78Å; F133-F179 AromaticContact CD1-CD2 3.88Å; F133-F179 HydrophobicContact CD1-CD2 3.88Å; F133-F179 HydrophobicContact CD1-CE2 4.21Å; F133-F179 HydrophobicContact CD1-CG 4.35Å; F133-F179 HydrophobicContact CD2-CB 3.6Å; F133-F179 HydrophobicContact CD2-CD2 4.16Å; F133-F179 AromaticContact CD2-CG 3.99Å; F133-F179 HydrophobicContact CD2-CG 3.99Å; F133-F179 HydrophobicContact CE1-CB 4.5Å; F133-F179 HydrophobicContact CE1-CD1 4.18Å; F133-F179 AromaticContact CE1-CD2 3.66Å; F133-F179 HydrophobicContact CE1-CD2 3.66Å; F133-F179 HydrophobicContact CE1-CE1 4.31Å; F133-F179 AromaticContact CE1-CE2 3.82Å; F133-F179 HydrophobicContact CE1-CE2 3.82Å; F133-F179 AromaticContact CE1-CG 3.85Å; F133-F179 HydrophobicContact CE1-CG 3.85Å; F133-F179 HydrophobicContact CE1-CZ 4.14Å; F133-F179 HydrophobicContact CE2-CB 3.27Å; F133-F179 AromaticContact CE2-CD1 3.97Å; F133-F179 HydrophobicContact CE2-CD1 3.97Å; F133-F179 AromaticContact CE2-CD2 3.99Å; F133-F179 HydrophobicContact CE2-CD2 3.99Å; F133-F179 AromaticContact CE2-CG 3.48Å; F133-F179 HydrophobicContact CE2-CG 3.48Å; F133-F179 VanDerWaalsContact CE2-CG 3.48Å; F133-F179 HydrophobicContact CG-CB 4.37Å; F133-F179 HydrophobicContact CG-CD2 4.12Å; F133-F179 HydrophobicContact CG-CG 4.41Å; F133-F179 HydrophobicContact CZ-CB 3.77Å; F133-F179 AromaticContact CZ-CD1 3.56Å; F133-F179 HydrophobicContact CZ-CD1 3.56Å; F133-F179 AromaticContact CZ-CD2 3.73Å; F133-F179 HydrophobicContact CZ-CD2 3.73Å; F133-F179 HydrophobicContact CZ-CE1 4.03Å; F133-F179 HydrophobicContact CZ-CE2 4.18Å; F133-F179 AromaticContact CZ-CG 3.39Å; F133-F179 HydrophobicContact CZ-CG 3.39Å; F133-F179 HydrophobicContact CZ-CZ 4.32Å; F133-F220 HydrophobicContact CE1-CB 3.88Å
134	T	94.4	Very high	91.6	Very high	0 Å²	0	17.7 Å²	17.7	0%	0	9%	0.088	C	C	.	.	H	α-helix	trans	-65.5	-41.3	-177.8	58.8	0	0	0	0	111.8	A94 Y130 N131 T138 I172 W173 A176	A94-T134 VanDerWaalsContact CB-OG1 3.25Å; A94-T134 WeakPolarHBondContact CB-OG1 3.27Å; Y130-T134 HydrophobicContact CD1-CG2 4.33Å; Y130-T134 WeakPolarHBondContact O-CB 3.37Å; Y130-T134 WeakPolarHBondContact O-CG2 3.13Å; Y130-T134 PolarHBondContact O-N 3.05Å; Y130-T134 PolarHBondContact O-OG1 3.45Å; N131-T134 PolarHBondContact O-N 3.39Å; N131-T134 PolarHBondContact O-OG1 3.21Å; T134-T138 WeakPolarHBondContact O-CB 3.26Å; T134-T138 PolarHBondContact O-N 3.1Å; T134-T138 PolarHBondContact O-OG1 3.5Å; T134-I172 HydrophobicContact CG2-CG2 4.26Å; T134-W173 HydrophobicContact CG2-CD2 3.91Å; T134-W173 HydrophobicContact CG2-CE3 3.83Å; T134-W173 HydrophobicContact CG2-CG 4.5Å; T134-W173 HydrophobicContact CG2-CH2 4.28Å; T134-W173 HydrophobicContact CG2-CZ2 4.36Å; T134-W173 HydrophobicContact CG2-CZ3 4.03Å; T134-A176 HydrophobicContact CG2-CB 3.44Å; T134-A176 VanDerWaalsContact CG2-CB 3.44Å
135	S	91.5	Very high	91.5	Very high	0 Å²	0	18 Å²	18	0%	0	9%	0.089	C	C	.	.	H	α-helix	trans	-63.1	-47.2	177.6	-67	0	0	0	0	111	L91 D95 N131 F133 T138 L139	L91-S135 VanDerWaalsContact CD1-CA 3.5Å; L91-S135 WeakPolarHBondContact CD1-OG 3.39Å; D95-S135 PolarHBondContact OD1-OG 3.11Å; N131-S135 PolarHBondContact ND2-OG 3.47Å; N131-S135 WeakPolarHBondContact O-CB 3.48Å; N131-S135 PolarHBondContact O-N 3.04Å; N131-S135 PolarHBondContact O-OG 3.49Å; F133-S135 PolarHBondContact O-N 2.89Å; S135-T138 PolarHBondContact O-N 2.87Å; S135-L139 WeakPolarHBondContact O-CG 3.26Å; S135-L139 PolarHBondContact O-N 3.46Å
136	T	91.1	Very high	91.2	Very high	0 Å²	0	20.5 Å²	20.5	0%	0	10%	0.098	C	C	.	.	H	α-helix	trans	-66.1	-45.5	179.5	-64.2	0	0	0	0	113.1	M132 F133 T138 L139 T140 S221 P225 F270	M132-T136 VanDerWaalsContact O-CB 3.31Å; M132-T136 WeakPolarHBondContact O-CB 3.5Å; M132-T136 PolarHBondContact O-N 2.77Å; M132-T136 PolarHBondContact O-OG1 3.21Å; F133-T136 PolarHBondContact O-N 2.92Å; T136-T138 VanDerWaalsContact C-N 3.3Å; T136-T138 PolarHBondContact O-N 3.35Å; T136-L139 PolarHBondContact O-N 2.92Å; T136-T140 WeakPolarHBondContact O-CB 3.24Å; T136-T140 PolarHBondContact O-N 2.93Å; T136-T140 PolarHBondContact O-OG1 3.37Å; T136-S221 WeakPolarHBondContact CG2-O 3.38Å; T136-S221 PolarHBondContact OG1-O 2.99Å; T136-P225 HydrophobicContact CG2-CB 3.17Å; T136-P225 HydrophobicContact CG2-CG 3.27Å; T136-F270 HydrophobicContact CG2-CE2 4.42Å; T136-F270 HydrophobicContact CG2-CZ 3.79Å; T136-F270 WeakPolarHBondContact OG1-CE2 3.33Å; T136-F270 WeakPolarHBondContact OG1-CZ 3.5Å
137	F	94.2	Very high	90.9	Very high	29 Å²	29	23 Å²	23	13%	0.127	11%	0.107	C	C	.	.	H	α-helix	trans	-65.3	-36.1	176.6	-64.6	-25	0	0	0	111.7	F133 T140 M141 I172 L175	F133-F137 HydrophobicContact CB-CD2 4.34Å; F133-F137 HydrophobicContact CB-CE2 3.98Å; F133-F137 HydrophobicContact CD1-CE1 4.41Å; F133-F137 AromaticContact CD1-CE2 3.92Å; F133-F137 HydrophobicContact CD1-CE2 3.92Å; F133-F137 AromaticContact CD1-CZ 3.66Å; F133-F137 HydrophobicContact CD1-CZ 3.66Å; F133-F137 HydrophobicContact CE1-CZ 4.43Å; F133-F137 HydrophobicContact CG-CE2 4.39Å; F133-F137 WeakPolarHBondContact O-CB 3.19Å; F133-F137 VanDerWaalsContact O-CD2 3.24Å; F133-F137 WeakPolarHBondContact O-CD2 3.15Å; F133-F137 WeakPolarHBondContact O-CG 3.25Å; F133-F137 PolarHBondContact O-N 3.26Å; F137-T140 PolarHBondContact O-N 2.96Å; F137-M141 WeakPolarHBondContact O-CB 3.32Å; F137-M141 PolarHBondContact O-N 3.42Å; F137-I172 HydrophobicContact CB-CG1 4.2Å; F137-I172 HydrophobicContact CB-CG2 3.87Å; F137-I172 HydrophobicContact CD2-CG2 4.49Å; F137-L175 HydrophobicContact CD2-CB 4.44Å; F137-L175 HydrophobicContact CD2-CD2 3.84Å; F137-L175 HydrophobicContact CD2-CG 4.15Å; F137-L175 HydrophobicContact CE1-CD2 4.43Å; F137-L175 HydrophobicContact CE2-CB 4.22Å; F137-L175 HydrophobicContact CE2-CD2 3.54Å; F137-L175 HydrophobicContact CE2-CG 3.57Å; F137-L175 HydrophobicContact CG-CD2 4.42Å; F137-L175 HydrophobicContact CZ-CD2 3.86Å; F137-L175 HydrophobicContact CZ-CG 4.12Å
138	T	92.8	Very high	90.7	Very high	0 Å²	0	22.4 Å²	22.4	0%	0	10%	0.104	C	C	.	.	H	α-helix	trans	-64.8	-45.4	174.4	-58.4	0	0	0	0	111.1	Y87 N90 L91 T134 S135 T136 T140 M141 M142	Y87-T138 WeakPolarHBondContact O-CG2 3.37Å; N90-T138 HydrophobicContact CB-CG2 4.41Å; N90-T138 PolarHBondContact ND2-OG1 3.4Å; L91-T138 HydrophobicContact CB-CG2 4.16Å; T134-T138 WeakPolarHBondContact O-CB 3.26Å; T134-T138 PolarHBondContact O-N 3.1Å; T134-T138 PolarHBondContact O-OG1 3.5Å; S135-T138 PolarHBondContact O-N 2.87Å; T136-T138 VanDerWaalsContact C-N 3.3Å; T136-T138 PolarHBondContact O-N 3.35Å; T138-T140 VanDerWaalsContact C-N 3.32Å; T138-T140 PolarHBondContact O-N 3.03Å; T138-M141 PolarHBondContact O-N 2.84Å; T138-M142 HydrophobicContact CG2-CG 4.43Å; T138-M142 HydrophobicContact CG2-SD 4.29Å; T138-M142 WeakPolarHBondContact O-CB 3.21Å; T138-M142 VanDerWaalsContact O-CG 3.29Å; T138-M142 WeakPolarHBondContact O-CG 3.26Å; T138-M142 PolarHBondContact O-N 2.61Å
139	L	87.6	Confident	90.4	Very high	8 Å²	8	22.3 Å²	22.3	4%	0.042	11%	0.107	C	C	.	.	H	α-helix	trans	-61.9	-39.8	175.7	-74.4	172.3	0	0	0	112.3	L91 S135 T136 M142 S143 V266 F270	L91-L139 HydrophobicContact CD2-CD2 4.23Å; S135-L139 WeakPolarHBondContact O-CG 3.26Å; S135-L139 PolarHBondContact O-N 3.46Å; T136-L139 PolarHBondContact O-N 2.92Å; L139-M142 PolarHBondContact O-N 3.49Å; L139-S143 WeakPolarHBondContact O-CB 3.12Å; L139-S143 PolarHBondContact O-N 2.87Å; L139-S143 PolarHBondContact O-OG 2.83Å; L139-V266 HydrophobicContact CD2-CG1 4.03Å; L139-F270 HydrophobicContact CD1-CB 4.42Å; L139-F270 HydrophobicContact CD1-CD2 3.38Å; L139-F270 HydrophobicContact CD1-CE2 3.87Å; L139-F270 HydrophobicContact CD1-CG 4.06Å
140	T	91.9	Very high	89.9	Confident	15 Å²	15	22.2 Å²	22.2	9%	0.092	11%	0.109	C	C	.	.	H	α-helix	trans	-60.9	-48	174	-56	0	0	0	0	110.4	T136 F137 T138 M142 S143 V144 I228 I229	T136-T140 WeakPolarHBondContact O-CB 3.24Å; T136-T140 PolarHBondContact O-N 2.93Å; T136-T140 PolarHBondContact O-OG1 3.37Å; F137-T140 PolarHBondContact O-N 2.96Å; T138-T140 VanDerWaalsContact C-N 3.32Å; T138-T140 PolarHBondContact O-N 3.03Å; T140-M142 PolarHBondContact O-N 3.11Å; T140-S143 WeakPolarHBondContact O-CA 3.49Å; T140-S143 VanDerWaalsContact O-CB 3.3Å; T140-S143 WeakPolarHBondContact O-CB 3.35Å; T140-S143 PolarHBondContact O-N 3.39Å; T140-S143 VanDerWaalsContact O-N 3.1Å; T140-V144 WeakPolarHBondContact O-CG2 3.34Å; T140-V144 PolarHBondContact O-N 3.43Å; T140-I228 HydrophobicContact CG2-CB 3.92Å; T140-I228 HydrophobicContact CG2-CD1 4.25Å; T140-I228 HydrophobicContact CG2-CG2 3.52Å; T140-I229 HydrophobicContact CG2-CG1 4.43Å
141	M	92.2	Very high	89.5	Confident	58 Å²	58	20.9 Å²	20.9	29%	0.286	11%	0.105	S	C	.	.	H	α-helix	trans	-65.9	-38.3	179	-168.4	57.9	55.8	0	0	112.8	Y87 F137 T138 S143 V144 D145 V168 I172	Y87-M141 HydrophobicContact CD1-CG 4.25Å; Y87-M141 HydrophobicContact CE1-CB 4.4Å; Y87-M141 HydrophobicContact CE1-CG 3.58Å; Y87-M141 HydrophobicContact CE2-CG 4.25Å; F137-M141 WeakPolarHBondContact O-CB 3.32Å; F137-M141 PolarHBondContact O-N 3.42Å; T138-M141 PolarHBondContact O-N 2.84Å; M141-S143 PolarHBondContact O-N 2.98Å; M141-V144 PolarHBondContact O-N 2.79Å; M141-V144 HydrophobicContact SD-CB 4.43Å; M141-D145 WeakPolarHBondContact O-CB 3.43Å; M141-D145 PolarHBondContact O-N 3.11Å; M141-V168 HydrophobicContact CE-CG1 3.81Å; M141-V168 HydrophobicContact CG-CG1 3.64Å; M141-V168 HydrophobicContact SD-CG1 3.88Å; M141-I172 HydrophobicContact CB-CD1 4.25Å
142	M	88.2	Confident	89.2	Confident	23 Å²	23	23.9 Å²	23.9	11%	0.113	12%	0.119	C	C	.	.	H	α-helix	trans	-60.2	-38.1	172	-74	179.4	70.5	0	0	111.2	T84 Y87 I88 T138 L139 T140 D145 R146 Y317	T84-M142 HydrophobicContact CG2-CE 4.43Å; Y87-M142 HydrophobicContact CD2-CG 4.34Å; Y87-M142 HydrophobicContact CG-CG 4.12Å; I88-M142 HydrophobicContact CD1-CE 4.32Å; I88-M142 HydrophobicContact CG1-CE 3.66Å; I88-M142 HydrophobicContact CG1-SD 4.42Å; T138-M142 HydrophobicContact CG2-CG 4.43Å; T138-M142 HydrophobicContact CG2-SD 4.29Å; T138-M142 WeakPolarHBondContact O-CB 3.21Å; T138-M142 VanDerWaalsContact O-CG 3.29Å; T138-M142 WeakPolarHBondContact O-CG 3.26Å; T138-M142 PolarHBondContact O-N 2.61Å; L139-M142 PolarHBondContact O-N 3.49Å; T140-M142 PolarHBondContact O-N 3.11Å; M142-D145 PolarHBondContact O-N 3.47Å; M142-R146 VanDerWaalsContact O-CG 3.27Å; M142-R146 WeakPolarHBondContact O-CG 3.34Å; M142-R146 PolarHBondContact O-N 2.95Å; M142-Y317 HydrophobicContact CE-CE1 4.42Å
143	S	86.5	Confident	88.9	Confident	5 Å²	5	26.9 Å²	26.9	4%	0.035	14%	0.14	C	C	.	.	H	α-helix	trans	-66.3	-41.8	176.4	-54.3	0	0	0	0	111.6	L139 T140 M141 R146 Y147 Y233	L139-S143 WeakPolarHBondContact O-CB 3.12Å; L139-S143 PolarHBondContact O-N 2.87Å; L139-S143 PolarHBondContact O-OG 2.83Å; T140-S143 WeakPolarHBondContact O-CA 3.49Å; T140-S143 VanDerWaalsContact O-CB 3.3Å; T140-S143 WeakPolarHBondContact O-CB 3.35Å; T140-S143 PolarHBondContact O-N 3.39Å; T140-S143 VanDerWaalsContact O-N 3.1Å; M141-S143 PolarHBondContact O-N 2.98Å; S143-R146 PolarHBondContact O-N 3.13Å; S143-Y147 WeakPolarHBondContact O-CB 3.44Å; S143-Y147 PolarHBondContact O-N 3.35Å; S143-Y233 WeakPolarHBondContact CA-OH 3.48Å; S143-Y233 WeakPolarHBondContact CB-OH 3.24Å; S143-Y233 WeakPolarHBondContact OG-CE2 3.26Å; S143-Y233 PolarHBondContact OG-OH 3.46Å
144	V	90.5	Very high	88.7	Confident	38 Å²	38	33.4 Å²	33.4	23%	0.23	17%	0.173	C	C	.	.	H	α-helix	trans	-64.5	-44.8	173.3	175	0	0	0	0	111.6	T140 M141 R146 Y147 I148 I228	T140-V144 WeakPolarHBondContact O-CG2 3.34Å; T140-V144 PolarHBondContact O-N 3.43Å; M141-V144 PolarHBondContact O-N 2.79Å; M141-V144 HydrophobicContact SD-CB 4.43Å; V144-R146 VanDerWaalsContact C-N 3.29Å; V144-R146 PolarHBondContact O-N 3.33Å; V144-Y147 WeakPolarHBondContact O-CB 3.5Å; V144-Y147 PolarHBondContact O-N 2.86Å; V144-I148 HydrophobicContact CG1-CD1 3.79Å; V144-I148 HydrophobicContact CG1-CG1 4.33Å; V144-I148 WeakPolarHBondContact O-CG1 3.37Å; V144-I148 PolarHBondContact O-N 3Å; V144-I228 HydrophobicContact CG2-CG2 4.42Å
145	D	88.9	Confident	88.4	Confident	9 Å²	9	39.6 Å²	39.6	5%	0.048	20%	0.2	C	C	.	.	H	α-helix	trans	-55.5	-44.4	176.2	176.7	68.2	0	0	0	111.3	T84 Y87 M141 M142 I148 A149 R160	T84-D145 PolarHBondContact OG1-OD2 3.31Å; Y87-D145 HydrophobicContact CE2-CB 4.14Å; M141-D145 WeakPolarHBondContact O-CB 3.43Å; M141-D145 PolarHBondContact O-N 3.11Å; M142-D145 PolarHBondContact O-N 3.47Å; D145-I148 PolarHBondContact O-N 3.21Å; D145-A149 WeakPolarHBondContact O-CB 3.38Å; D145-A149 PolarHBondContact O-N 3.43Å; D145-R160 WeakPolarHBondContact OD1-CG 3.36Å; D145-R160 IonicContact OD1-CZ 2.71Å; D145-R160 IonicContact OD1-NE 3.98Å; D145-R160 PolarHBondContact OD1-NE 3.49Å; D145-R160 IonicContact OD1-NH2 2.69Å; D145-R160 IonicContact OD2-CZ 3.63Å; D145-R160 IonicContact OD2-NE 3.63Å; D145-R160 PolarHBondContact OD2-NE 2.59Å; D145-R160 IonicContact OD2-NH2 2.64Å; D145-R160 PolarHBondContact OD2-NH2 3.05Å
146	R	84.4	Confident	88.2	Confident	67 Å²	67	40.1 Å²	40.1	25%	0.253	20%	0.204	S	C	.	.	H	α-helix	trans	-69.1	-41.4	176.9	-66.9	-62.9	175.7	-178.6	0.3	112.6	M142 S143 V144 I148 A149 I150	M142-R146 VanDerWaalsContact O-CG 3.27Å; M142-R146 WeakPolarHBondContact O-CG 3.34Å; M142-R146 PolarHBondContact O-N 2.95Å; S143-R146 PolarHBondContact O-N 3.13Å; V144-R146 VanDerWaalsContact C-N 3.29Å; V144-R146 PolarHBondContact O-N 3.33Å; R146-I148 PolarHBondContact O-N 3.42Å; R146-A149 PolarHBondContact O-N 2.63Å; R146-I150 PolarHBondContact O-N 2.9Å; R146-I150 VanDerWaalsContact O-N 3.15Å
147	Y	87.3	Confident	88	Confident	53 Å²	53	46.7 Å²	46.7	21%	0.208	24%	0.239	C	C	.	.	H	α-helix	trans	-57.4	-48.3	173.6	166.4	-100.8	0	0	0	111.3	S143 V144 A149 I150 C151 H152 L235	S143-Y147 WeakPolarHBondContact O-CB 3.44Å; S143-Y147 PolarHBondContact O-N 3.35Å; V144-Y147 WeakPolarHBondContact O-CB 3.5Å; V144-Y147 PolarHBondContact O-N 2.86Å; Y147-A149 PolarHBondContact O-N 3.1Å; Y147-I150 PolarHBondContact O-N 3.26Å; Y147-C151 HydrophobicContact CD2-CB 4.07Å; Y147-C151 WeakPolarHBondContact CD2-SG 3.45Å; Y147-C151 HydrophobicContact CE2-CB 3.67Å; Y147-C151 WeakPolarHBondContact CE2-SG 3.48Å; Y147-C151 VanDerWaalsContact O-CB 3.27Å; Y147-C151 WeakPolarHBondContact O-CB 3.43Å; Y147-C151 PolarHBondContact O-N 3.02Å; Y147-H152 AromaticContact CE1-CD2 3.84Å; Y147-H152 AromaticContact CE1-NE2 3.89Å; Y147-H152 AromaticContact CZ-CD2 3.96Å; Y147-H152 AromaticContact CZ-NE2 3.67Å; Y147-H152 PolarHBondContact OH-NE2 3.37Å; Y147-H152 VanDerWaalsContact OH-NE2 3.08Å; Y147-L235 HydrophobicContact CD2-CB 4.15Å; Y147-L235 HydrophobicContact CE2-CB 3.65Å; Y147-L235 HydrophobicContact CE2-CD1 4.16Å
148	I	89.1	Confident	87.8	Confident	31 Å²	31	50.6 Å²	50.6	16%	0.159	26%	0.261	C	S	.	.	H	α-helix	trans	-61.8	-45.7	178.6	-67.5	169	0	0	0	110.5	V144 D145 R146 I150 H152 A156 I159	V144-I148 HydrophobicContact CG1-CD1 3.79Å; V144-I148 HydrophobicContact CG1-CG1 4.33Å; V144-I148 WeakPolarHBondContact O-CG1 3.37Å; V144-I148 PolarHBondContact O-N 3Å; D145-I148 PolarHBondContact O-N 3.21Å; R146-I148 PolarHBondContact O-N 3.42Å; I148-I150 VanDerWaalsContact C-N 3.26Å; I148-I150 PolarHBondContact O-N 2.9Å; I148-H152 CarbonylContact O-C 3.51Å; I148-H152 WeakPolarHBondContact O-CA 3.49Å; I148-H152 PolarHBondContact O-N 3.46Å; I148-A156 HydrophobicContact CG2-CB 4.03Å; I148-I159 HydrophobicContact CD1-CG2 4.47Å
149	A	85.1	Confident	87.7	Confident	24 Å²	24	54.2 Å²	54.2	20%	0.198	28%	0.279	C	S	.	.	H	α-helix	trans	-56.7	-38.1	179.6	0	0	0	0	0	113.8	D145 R146 Y147	D145-A149 WeakPolarHBondContact O-CB 3.38Å; D145-A149 PolarHBondContact O-N 3.43Å; R146-A149 PolarHBondContact O-N 2.63Å; Y147-A149 PolarHBondContact O-N 3.1Å
150	I	82	Confident	87.8	Confident	42 Å²	42	57.2 Å²	57.2	22%	0.215	29%	0.29	C	S	.	.	H	α-helix	trans	-92.8	-43.3	-173.7	-71.1	165.3	0	0	0	111.6	R146 Y147 I148 M236 L240 I259	R146-I150 PolarHBondContact O-N 2.9Å; R146-I150 VanDerWaalsContact O-N 3.15Å; Y147-I150 PolarHBondContact O-N 3.26Å; I148-I150 VanDerWaalsContact C-N 3.26Å; I148-I150 PolarHBondContact O-N 2.9Å; I150-M236 HydrophobicContact CB-CG 4.25Å; I150-M236 HydrophobicContact CD1-CG 3.86Å; I150-M236 HydrophobicContact CD1-SD 3.47Å; I150-M236 WeakPolarHBondContact CD1-SD 3.32Å; I150-M236 HydrophobicContact CG2-CG 4.02Å; I150-L240 HydrophobicContact CG2-CD2 3.63Å; I150-L240 HydrophobicContact CG2-CG 3.94Å; I150-I259 HydrophobicContact CD1-CG2 4.38Å
151	C	85.1	Confident	87.9	Confident	13 Å²	13	58.7 Å²	58.7	9%	0.088	30%	0.299	C	S	.	.	H	α-helix	trans	-86.6	-27.3	-173.7	-60.3	0	0	0	0	112.8	Y147 R239	Y147-C151 HydrophobicContact CD2-CB 4.07Å; Y147-C151 WeakPolarHBondContact CD2-SG 3.45Å; Y147-C151 HydrophobicContact CE2-CB 3.67Å; Y147-C151 WeakPolarHBondContact CE2-SG 3.48Å; Y147-C151 VanDerWaalsContact O-CB 3.27Å; Y147-C151 WeakPolarHBondContact O-CB 3.43Å; Y147-C151 PolarHBondContact O-N 3.02Å; C151-R239 HydrophobicContact CB-CG 4.41Å
152	H	86.6	Confident	87.8	Confident	69 Å²	69	58.5 Å²	58.5	32%	0.319	30%	0.303	S	S	.	.			trans	-134.3	63	-173.7	-59.2	-75.8	0	0	0	111.8	Y147 I148 I154 K155 A156	Y147-H152 AromaticContact CE1-CD2 3.84Å; Y147-H152 AromaticContact CE1-NE2 3.89Å; Y147-H152 AromaticContact CZ-CD2 3.96Å; Y147-H152 AromaticContact CZ-NE2 3.67Å; Y147-H152 PolarHBondContact OH-NE2 3.37Å; Y147-H152 VanDerWaalsContact OH-NE2 3.08Å; I148-H152 CarbonylContact O-C 3.51Å; I148-H152 WeakPolarHBondContact O-CA 3.49Å; I148-H152 PolarHBondContact O-N 3.46Å; H152-I154 VanDerWaalsContact C-N 3.29Å; H152-I154 PolarHBondContact O-N 2.87Å; H152-K155 HydrophobicContact CB-CB 4.18Å; H152-K155 HydrophobicContact CB-CD 4.34Å; H152-K155 HydrophobicContact CB-CG 4.49Å; H152-K155 PolarHBondContact O-N 3.45Å; H152-A156 WeakPolarHBondContact O-CB 3.42Å; H152-A156 PolarHBondContact O-N 2.89Å
153	P	84.5	Confident	88	Confident	80 Å²	80	64 Å²	64	52%	0.519	33%	0.327	S	S	.	.	H	α-helix	trans	-61.4	-31.8	-170.1	24.5	-35.1	0	0	0	114.2	A156	P153-A156 WeakPolarHBondContact O-CB 3.36Å
154	I	88.3	Confident	88.4	Confident	138 Å²	138	68.4 Å²	68.4	71%	0.708	35%	0.346	S	S	*	.	H	α-helix	trans	-69.2	-50.8	177.7	-58.4	174.4	0	0	0	109.9	H152 A156 L157	H152-I154 VanDerWaalsContact C-N 3.29Å; H152-I154 PolarHBondContact O-N 2.87Å; I154-A156 PolarHBondContact O-N 2.93Å; I154-L157 WeakPolarHBondContact O-CB 3.34Å; I154-L157 PolarHBondContact O-N 3.48Å
155	K	89.1	Confident	88.6	Confident	130 Å²	130	66.7 Å²	66.7	57%	0.565	34%	0.336	S	S	*	.	H	α-helix	trans	-62.2	-30.1	176.5	-62.8	-175.9	178.4	179.6	0	112.4	H152 L157 D158 I159	H152-K155 HydrophobicContact CB-CB 4.18Å; H152-K155 HydrophobicContact CB-CD 4.34Å; H152-K155 HydrophobicContact CB-CG 4.49Å; H152-K155 PolarHBondContact O-N 3.45Å; K155-L157 PolarHBondContact O-N 3.33Å; K155-D158 PolarHBondContact O-N 3.5Å; K155-I159 HydrophobicContact CB-CD1 4.12Å; K155-I159 WeakPolarHBondContact O-CG1 3.42Å; K155-I159 PolarHBondContact O-N 3.35Å; K155-I159 VanDerWaalsContact O-N 3.09Å
156	A	87.7	Confident	88.8	Confident	10 Å²	10	72.6 Å²	72.6	8%	0.083	36%	0.361	C	S	.	.	H	α-helix	trans	-60.9	-30.4	178.8	0	0	0	0	0	112.8	I148 H152 P153 I154 D158 R160	I148-A156 HydrophobicContact CG2-CB 4.03Å; H152-A156 WeakPolarHBondContact O-CB 3.42Å; H152-A156 PolarHBondContact O-N 2.89Å; P153-A156 WeakPolarHBondContact O-CB 3.36Å; I154-A156 PolarHBondContact O-N 2.93Å; A156-D158 VanDerWaalsContact C-N 3.31Å; A156-D158 PolarHBondContact O-N 2.89Å; A156-R160 HydrophobicContact CB-CG 4.25Å; A156-R160 VanDerWaalsContact O-CB 3.24Å; A156-R160 WeakPolarHBondContact O-CB 3.29Å; A156-R160 WeakPolarHBondContact O-CG 3.4Å; A156-R160 PolarHBondContact O-N 3.14Å
157	L	86.3	Confident	89.4	Confident	138 Å²	138	73 Å²	73	72%	0.723	37%	0.371	S	S	*	.	H	α-helix	trans	-62.8	-38.6	177.2	-64.5	171.9	0	0	0	111.8	I154 K155	I154-L157 WeakPolarHBondContact O-CB 3.34Å; I154-L157 PolarHBondContact O-N 3.48Å; K155-L157 PolarHBondContact O-N 3.33Å
158	D	89.8	Confident	89.8	Confident	111 Å²	111	72.3 Å²	72.3	59%	0.594	37%	0.372	S	S	*	.	H	α-helix	trans	-84.4	-33.4	-178.4	-59.8	-33	0	0	0	112.6	K155 A156 K164	K155-D158 PolarHBondContact O-N 3.5Å; A156-D158 VanDerWaalsContact C-N 3.31Å; A156-D158 PolarHBondContact O-N 2.89Å; D158-K164 PolarHBondContact O-NZ 3.12Å
159	I	89.9	Confident	90.1	Very high	76 Å²	76	71.5 Å²	71.5	39%	0.39	37%	0.368	S	S	.	.	H	α-helix	trans	-88.2	-39.9	-171.5	-61.9	170.1	0	0	0	111.8	I148 K155 T161 K164	I148-I159 HydrophobicContact CD1-CG2 4.47Å; K155-I159 HydrophobicContact CB-CD1 4.12Å; K155-I159 WeakPolarHBondContact O-CG1 3.42Å; K155-I159 PolarHBondContact O-N 3.35Å; K155-I159 VanDerWaalsContact O-N 3.09Å; I159-T161 PolarHBondContact O-N 3.41Å; I159-K164 WeakPolarHBondContact O-CD 2.97Å
160	R	91.1	Very high	90.7	Very high	72 Å²	72	75.2 Å²	75.2	27%	0.272	39%	0.388	S	S	.	.			trans	-84.7	48.4	-170.6	-57.2	-178.6	71.7	-150.2	3	112.7	A83 T84 D145 A156	A83-R160 HydrophobicContact CB-CB 4.28Å; A83-R160 WeakPolarHBondContact CB-O 3.35Å; T84-R160 PolarHBondContact OG1-NH2 3.02Å; D145-R160 WeakPolarHBondContact OD1-CG 3.36Å; D145-R160 IonicContact OD1-CZ 2.71Å; D145-R160 IonicContact OD1-NE 3.98Å; D145-R160 PolarHBondContact OD1-NE 3.49Å; D145-R160 IonicContact OD1-NH2 2.69Å; D145-R160 IonicContact OD2-CZ 3.63Å; D145-R160 IonicContact OD2-NE 3.63Å; D145-R160 PolarHBondContact OD2-NE 2.59Å; D145-R160 IonicContact OD2-NH2 2.64Å; D145-R160 PolarHBondContact OD2-NH2 3.05Å; A156-R160 HydrophobicContact CB-CG 4.25Å; A156-R160 VanDerWaalsContact O-CB 3.24Å; A156-R160 WeakPolarHBondContact O-CB 3.29Å; A156-R160 WeakPolarHBondContact O-CG 3.4Å; A156-R160 PolarHBondContact O-N 3.14Å
161	T	92.4	Very high	91.4	Very high	46 Å²	46	76.8 Å²	76.8	28%	0.282	40%	0.402	S	S	.	.			trans	-91.9	146.8	176.6	64.2	0	0	0	0	111	I159 H163 K164 A165	I159-T161 PolarHBondContact O-N 3.41Å; T161-H163 PolarHBondContact O-N 3.43Å; T161-K164 PolarHBondContact O-N 3.1Å; T161-K164 WeakPolarHBondContact OG1-CB 3.25Å; T161-K164 VanDerWaalsContact OG1-CG 3.3Å; T161-K164 WeakPolarHBondContact OG1-CG 3.4Å; T161-K164 PolarHBondContact OG1-N 2.87Å; T161-A165 PolarHBondContact O-N 3.44Å
162	P	90.6	Very high	92	Very high	54 Å²	54	76.6 Å²	76.6	35%	0.351	40%	0.4	S	S	.	.	H	α-helix	trans	-55.6	-37	176.3	-29.9	38	0	0	0	113.6	K81 I86 A165 K166	K81-P162 VanDerWaalsContact O-CG 3.26Å; K81-P162 WeakPolarHBondContact O-CG 3.21Å; I86-P162 VanDerWaalsContact CD1-CA 3.49Å; I86-P162 HydrophobicContact CD1-CB 3.48Å; I86-P162 VanDerWaalsContact CD1-CB 3.48Å; I86-P162 WeakPolarHBondContact CD1-O 3.2Å; P162-A165 PolarHBondContact O-N 3.37Å; P162-K166 WeakPolarHBondContact O-CG 3.29Å; P162-K166 PolarHBondContact O-N 3.48Å; P162-K166 VanDerWaalsContact O-N 3.09Å
163	H	92.9	Very high	92.5	Very high	137 Å²	137	76.3 Å²	76.3	63%	0.634	40%	0.396	S	S	*	.	H	α-helix	trans	-63.3	-50.3	178	-177.7	-85.3	0	0	0	111.6	T161 A165 K166 V167	T161-H163 PolarHBondContact O-N 3.43Å; H163-A165 VanDerWaalsContact C-N 3.32Å; H163-A165 PolarHBondContact O-N 3.15Å; H163-K166 WeakPolarHBondContact O-CB 3.34Å; H163-K166 PolarHBondContact O-N 3.31Å; H163-V167 PolarHBondContact O-N 3.18Å; H163-V167 VanDerWaalsContact O-N 3.12Å
164	K	94.5	Very high	93	Very high	99 Å²	99	75.3 Å²	75.3	43%	0.43	39%	0.394	S	S	.	.	H	α-helix	trans	-61.4	-40.3	178	-71.7	179.2	179.3	177.5	0	111.7	D158 I159 T161 K166 V167 V168	D158-K164 PolarHBondContact O-NZ 3.12Å; I159-K164 WeakPolarHBondContact O-CD 2.97Å; T161-K164 PolarHBondContact O-N 3.1Å; T161-K164 WeakPolarHBondContact OG1-CB 3.25Å; T161-K164 VanDerWaalsContact OG1-CG 3.3Å; T161-K164 WeakPolarHBondContact OG1-CG 3.4Å; T161-K164 PolarHBondContact OG1-N 2.87Å; K164-K166 VanDerWaalsContact C-N 3.33Å; K164-K166 PolarHBondContact O-N 3.49Å; K164-V167 PolarHBondContact O-N 3.33Å; K164-V168 WeakPolarHBondContact O-CG2 3.16Å; K164-V168 PolarHBondContact O-N 3.49Å
165	A	94.1	Very high	93.4	Very high	1 Å²	1	73 Å²	73	1%	0.008	38%	0.383	C	S	.	.	H	α-helix	trans	-60.7	-39.6	175.8	0	0	0	0	0	112.8	A83 I86 Y87 T161 P162 H163 V168 N169	A83-A165 HydrophobicContact CB-CB 3.96Å; I86-A165 HydrophobicContact CB-CB 4.06Å; I86-A165 HydrophobicContact CD1-CB 4.44Å; I86-A165 HydrophobicContact CG2-CB 3.8Å; Y87-A165 HydrophobicContact CE1-CB 4.32Å; Y87-A165 HydrophobicContact CE2-CB 4.21Å; T161-A165 PolarHBondContact O-N 3.44Å; P162-A165 PolarHBondContact O-N 3.37Å; H163-A165 VanDerWaalsContact C-N 3.32Å; H163-A165 PolarHBondContact O-N 3.15Å; A165-V168 PolarHBondContact O-N 2.96Å; A165-N169 PolarHBondContact O-N 3.48Å
166	K	94.1	Very high	93.7	Very high	134 Å²	134	66.8 Å²	66.8	58%	0.583	36%	0.356	S	S	*	.	H	α-helix	trans	-63.1	-43.9	174.1	-72.1	177.8	-179.7	-174	0	112.2	I86 P162 H163 K164 V168 N169 V170	I86-K166 HydrophobicContact CD1-CG 4.22Å; I86-K166 HydrophobicContact CG2-CG 4.03Å; P162-K166 WeakPolarHBondContact O-CG 3.29Å; P162-K166 PolarHBondContact O-N 3.48Å; P162-K166 VanDerWaalsContact O-N 3.09Å; H163-K166 WeakPolarHBondContact O-CB 3.34Å; H163-K166 PolarHBondContact O-N 3.31Å; K164-K166 VanDerWaalsContact C-N 3.33Å; K164-K166 PolarHBondContact O-N 3.49Å; K166-V168 VanDerWaalsContact C-N 3.32Å; K166-V168 PolarHBondContact O-N 3.01Å; K166-N169 WeakPolarHBondContact O-CB 3.41Å; K166-N169 PolarHBondContact O-N 3.17Å; K166-V170 WeakPolarHBondContact O-CG2 3.31Å; K166-V170 PolarHBondContact O-N 3.33Å
167	V	96.6	Very high	94.1	Very high	75 Å²	75	67.6 Å²	67.6	46%	0.455	36%	0.361	S	S	.	.	H	α-helix	trans	-60	-45.4	176.4	175.1	0	0	0	0	110.3	H163 K164 N169 V170 C171	H163-V167 PolarHBondContact O-N 3.18Å; H163-V167 VanDerWaalsContact O-N 3.12Å; K164-V167 PolarHBondContact O-N 3.33Å; V167-N169 VanDerWaalsContact C-N 3.32Å; V167-N169 PolarHBondContact O-N 3.32Å; V167-V170 WeakPolarHBondContact O-CB 3.31Å; V167-V170 PolarHBondContact O-N 3.37Å; V167-V170 VanDerWaalsContact O-N 3.14Å; V167-C171 PolarHBondContact O-N 3.44Å; V167-C171 PolarHBondContact O-SG 2.89Å; V167-C171 VanDerWaalsContact O-SG 3.35Å
168	V	96.3	Very high	94.4	Very high	39 Å²	39	65.3 Å²	65.3	24%	0.236	35%	0.353	C	S	.	.	H	α-helix	trans	-60.8	-40.4	177	174.9	0	0	0	0	111.7	Y87 M141 K164 A165 K166 V170 C171 I172	Y87-V168 HydrophobicContact CE1-CB 4.11Å; Y87-V168 HydrophobicContact CE1-CG1 3.85Å; M141-V168 HydrophobicContact CE-CG1 3.81Å; M141-V168 HydrophobicContact CG-CG1 3.64Å; M141-V168 HydrophobicContact SD-CG1 3.88Å; K164-V168 WeakPolarHBondContact O-CG2 3.16Å; K164-V168 PolarHBondContact O-N 3.49Å; A165-V168 PolarHBondContact O-N 2.96Å; K166-V168 VanDerWaalsContact C-N 3.32Å; K166-V168 PolarHBondContact O-N 3.01Å; V168-V170 PolarHBondContact O-N 3.11Å; V168-C171 WeakPolarHBondContact O-CB 3.17Å; V168-C171 PolarHBondContact O-N 2.92Å; V168-I172 HydrophobicContact CG1-CD1 4.11Å; V168-I172 HydrophobicContact CG1-CG1 4.49Å; V168-I172 WeakPolarHBondContact O-CG1 3.15Å; V168-I172 PolarHBondContact O-N 3.43Å
169	N	95.9	Very high	94.4	Very high	14 Å²	14	61.8 Å²	61.8	8%	0.075	33%	0.332	C	S	.	.	H	α-helix	trans	-60.1	-44.6	174.1	-73.9	-12.3	0	0	0	111.9	I86 Y87 N90 A165 K166 V167 C171 I172 W173	I86-N169 WeakPolarHBondContact CG2-ND2 3.34Å; I86-N169 PolarHBondContact O-ND2 2.94Å; I86-N169 VanDerWaalsContact O-ND2 3.1Å; Y87-N169 WeakPolarHBondContact CD1-OD1 3.48Å; N90-N169 WeakPolarHBondContact CB-ND2 3.34Å; A165-N169 PolarHBondContact O-N 3.48Å; K166-N169 WeakPolarHBondContact O-CB 3.41Å; K166-N169 PolarHBondContact O-N 3.17Å; V167-N169 VanDerWaalsContact C-N 3.32Å; V167-N169 PolarHBondContact O-N 3.32Å; N169-C171 VanDerWaalsContact C-N 3.27Å; N169-C171 PolarHBondContact O-N 3.41Å; N169-I172 WeakPolarHBondContact O-CB 3.42Å; N169-I172 PolarHBondContact O-N 2.94Å; N169-W173 PolarHBondContact O-N 3.12Å
170	V	96.7	Very high	94.4	Very high	102 Å²	102	58.1 Å²	58.1	62%	0.618	31%	0.313	S	S	*	.	H	α-helix	trans	-58.9	-41.6	175.7	175.1	0	0	0	0	110.8	K166 V167 V168 I172 W173 A174	K166-V170 WeakPolarHBondContact O-CG2 3.31Å; K166-V170 PolarHBondContact O-N 3.33Å; V167-V170 WeakPolarHBondContact O-CB 3.31Å; V167-V170 PolarHBondContact O-N 3.37Å; V167-V170 VanDerWaalsContact O-N 3.14Å; V168-V170 PolarHBondContact O-N 3.11Å; V170-I172 VanDerWaalsContact C-N 3.34Å; V170-I172 PolarHBondContact O-N 3.34Å; V170-W173 PolarHBondContact O-N 3Å; V170-A174 PolarHBondContact O-N 2.92Å
171	C	97.1	Very high	94.5	Very high	75 Å²	75	59.2 Å²	59.2	51%	0.507	32%	0.323	S	S	.	.	H	α-helix	trans	-62.9	-38.1	173.9	-62.1	0	0	0	0	112.8	V167 V168 N169 A174 L175	V167-C171 PolarHBondContact O-N 3.44Å; V167-C171 PolarHBondContact O-SG 2.89Å; V167-C171 VanDerWaalsContact O-SG 3.35Å; V168-C171 WeakPolarHBondContact O-CB 3.17Å; V168-C171 PolarHBondContact O-N 2.92Å; N169-C171 VanDerWaalsContact C-N 3.27Å; N169-C171 PolarHBondContact O-N 3.41Å; C171-A174 PolarHBondContact O-N 3.45Å; C171-L175 WeakPolarHBondContact O-CB 3.48Å; C171-L175 PolarHBondContact O-N 3.32Å
172	I	96.9	Very high	94.4	Very high	8 Å²	8	59.6 Å²	59.6	4%	0.041	33%	0.327	C	S	.	.	H	α-helix	trans	-61.7	-45	175.7	-72.4	166.7	0	0	0	110.7	T134 F137 M141 V168 N169 V170 L175 A176	T134-I172 HydrophobicContact CG2-CG2 4.26Å; F137-I172 HydrophobicContact CB-CG1 4.2Å; F137-I172 HydrophobicContact CB-CG2 3.87Å; F137-I172 HydrophobicContact CD2-CG2 4.49Å; M141-I172 HydrophobicContact CB-CD1 4.25Å; V168-I172 HydrophobicContact CG1-CD1 4.11Å; V168-I172 HydrophobicContact CG1-CG1 4.49Å; V168-I172 WeakPolarHBondContact O-CG1 3.15Å; V168-I172 PolarHBondContact O-N 3.43Å; N169-I172 WeakPolarHBondContact O-CB 3.42Å; N169-I172 PolarHBondContact O-N 2.94Å; V170-I172 VanDerWaalsContact C-N 3.34Å; V170-I172 PolarHBondContact O-N 3.34Å; I172-L175 PolarHBondContact O-N 3.08Å; I172-A176 WeakPolarHBondContact O-CB 3.38Å; I172-A176 PolarHBondContact O-N 3.05Å
173	W	96.8	Very high	94.3	Very high	64 Å²	64	57 Å²	57	24%	0.242	31%	0.31	C	S	.	.	H	α-helix	trans	-65.2	-40.7	176.5	-77.3	98.6	0	0	0	112.4	N90 L93 L97 Y130 T134 N169 V170 L175 A176 S177	N90-W173 PolarHBondContact OD1-NE1 3.03Å; L93-W173 HydrophobicContact CD2-CZ2 4.22Å; L93-W173 HydrophobicContact CG-CZ2 4.48Å; L97-W173 HydrophobicContact CD1-CH2 4.01Å; Y130-W173 AromaticContact CD1-CE3 3.82Å; Y130-W173 HydrophobicContact CD1-CE3 3.82Å; Y130-W173 AromaticContact CD1-CZ3 3.8Å; Y130-W173 HydrophobicContact CD1-CZ3 3.8Å; Y130-W173 HydrophobicContact CE1-CE3 4.1Å; Y130-W173 HydrophobicContact CE1-CZ3 4.42Å; Y130-W173 HydrophobicContact CG-CZ3 4.26Å; T134-W173 HydrophobicContact CG2-CD2 3.91Å; T134-W173 HydrophobicContact CG2-CE3 3.83Å; T134-W173 HydrophobicContact CG2-CG 4.5Å; T134-W173 HydrophobicContact CG2-CH2 4.28Å; T134-W173 HydrophobicContact CG2-CZ2 4.36Å; T134-W173 HydrophobicContact CG2-CZ3 4.03Å; N169-W173 PolarHBondContact O-N 3.12Å; V170-W173 PolarHBondContact O-N 3Å; W173-L175 VanDerWaalsContact C-N 3.35Å; W173-A176 PolarHBondContact O-N 3.04Å; W173-S177 WeakPolarHBondContact O-CB 3.34Å; W173-S177 PolarHBondContact O-N 3.49Å; W173-S177 PolarHBondContact O-OG 3.32Å
174	A	96.9	Very high	94.2	Very high	59 Å²	59	54.2 Å²	54.2	49%	0.488	30%	0.298	S	S	.	.	H	α-helix	trans	-61.6	-44	174.7	0	0	0	0	0	111.4	V170 C171 S177	V170-A174 PolarHBondContact O-N 2.92Å; C171-A174 PolarHBondContact O-N 3.45Å; A174-S177 WeakPolarHBondContact O-CB 3.39Å; A174-S177 PolarHBondContact O-N 3.19Å
175	L	95.4	Very high	94.1	Very high	88 Å²	88	54.5 Å²	54.5	46%	0.461	31%	0.308	S	S	.	.	H	α-helix	trans	-67	-41.7	177.3	-174.8	62.1	0	0	0	112.1	F137 C171 I172 W173 S177 V178	F137-L175 HydrophobicContact CD2-CB 4.44Å; F137-L175 HydrophobicContact CD2-CD2 3.84Å; F137-L175 HydrophobicContact CD2-CG 4.15Å; F137-L175 HydrophobicContact CE1-CD2 4.43Å; F137-L175 HydrophobicContact CE2-CB 4.22Å; F137-L175 HydrophobicContact CE2-CD2 3.54Å; F137-L175 HydrophobicContact CE2-CG 3.57Å; F137-L175 HydrophobicContact CG-CD2 4.42Å; F137-L175 HydrophobicContact CZ-CD2 3.86Å; F137-L175 HydrophobicContact CZ-CG 4.12Å; C171-L175 WeakPolarHBondContact O-CB 3.48Å; C171-L175 PolarHBondContact O-N 3.32Å; I172-L175 PolarHBondContact O-N 3.08Å; W173-L175 VanDerWaalsContact C-N 3.35Å; L175-S177 PolarHBondContact O-N 3.4Å; L175-V178 VanDerWaalsContact O-CB 3.28Å; L175-V178 WeakPolarHBondContact O-CB 3.28Å; L175-V178 WeakPolarHBondContact O-CG2 3.29Å; L175-V178 PolarHBondContact O-N 3.42Å
176	A	95.7	Very high	93.7	Very high	0 Å²	0	56.4 Å²	56.4	0%	0	32%	0.317	C	S	.	.	H	α-helix	trans	-63.7	-32	174.7	0	0	0	0	0	112	Y130 F133 T134 I172 W173 V178 F179 G180	Y130-A176 HydrophobicContact CD1-CB 3.92Å; Y130-A176 HydrophobicContact CE1-CB 4.21Å; F133-A176 HydrophobicContact CB-CB 3.78Å; T134-A176 HydrophobicContact CG2-CB 3.44Å; T134-A176 VanDerWaalsContact CG2-CB 3.44Å; I172-A176 WeakPolarHBondContact O-CB 3.38Å; I172-A176 PolarHBondContact O-N 3.05Å; W173-A176 PolarHBondContact O-N 3.04Å; A176-V178 PolarHBondContact O-N 3.33Å; A176-F179 PolarHBondContact O-N 2.91Å; A176-G180 PolarHBondContact O-N 2.97Å
177	S	95.5	Very high	93.4	Very high	27 Å²	27	50 Å²	50	19%	0.189	29%	0.29	C	S	.	.	H	α-helix	trans	-63.8	-24.9	177.1	-58.3	0	0	0	0	113.2	Y130 W173 A174 L175 F179 I181	Y130-S177 WeakPolarHBondContact CE1-OG 3.3Å; Y130-S177 WeakPolarHBondContact OH-CA 3.41Å; Y130-S177 VanDerWaalsContact OH-CB 3.23Å; Y130-S177 WeakPolarHBondContact OH-CB 3.34Å; Y130-S177 PolarHBondContact OH-OG 2.93Å; W173-S177 WeakPolarHBondContact O-CB 3.34Å; W173-S177 PolarHBondContact O-N 3.49Å; W173-S177 PolarHBondContact O-OG 3.32Å; A174-S177 WeakPolarHBondContact O-CB 3.39Å; A174-S177 PolarHBondContact O-N 3.19Å; L175-S177 PolarHBondContact O-N 3.4Å; S177-F179 PolarHBondContact O-N 3.26Å; S177-I181 WeakPolarHBondContact O-CB 3.43Å; S177-I181 WeakPolarHBondContact O-CG1 3.24Å; S177-I181 PolarHBondContact O-N 2.9Å
178	V	93.8	Very high	92.9	Very high	91 Å²	91	47.2 Å²	47.2	55%	0.552	27%	0.273	S	S	*	.	H	α-helix	trans	-57.8	-28.8	172.6	180	0	0	0	0	111.3	L175 A176 P182	L175-V178 VanDerWaalsContact O-CB 3.28Å; L175-V178 WeakPolarHBondContact O-CB 3.28Å; L175-V178 WeakPolarHBondContact O-CG2 3.29Å; L175-V178 PolarHBondContact O-N 3.42Å; A176-V178 PolarHBondContact O-N 3.33Å; V178-P182 VanDerWaalsContact O-CD 3.25Å; V178-P182 WeakPolarHBondContact O-CD 3.35Å; V178-P182 VanDerWaalsContact O-CG 3.23Å; V178-P182 WeakPolarHBondContact O-CG 3.29Å
179	F	90	Very high	92.2	Very high	36 Å²	36	46 Å²	46	16%	0.158	27%	0.267	C	S	.	.	H	α-helix	trans	-105.2	-39.4	177.4	-59.3	-85	0	0	0	112.5	F133 A176 S177 I181 P182 A183 F220	F133-F179 AromaticContact CD1-CD2 3.88Å; F133-F179 HydrophobicContact CD1-CD2 3.88Å; F133-F179 HydrophobicContact CD1-CE2 4.21Å; F133-F179 HydrophobicContact CD1-CG 4.35Å; F133-F179 HydrophobicContact CD2-CB 3.6Å; F133-F179 HydrophobicContact CD2-CD2 4.16Å; F133-F179 AromaticContact CD2-CG 3.99Å; F133-F179 HydrophobicContact CD2-CG 3.99Å; F133-F179 HydrophobicContact CE1-CB 4.5Å; F133-F179 HydrophobicContact CE1-CD1 4.18Å; F133-F179 AromaticContact CE1-CD2 3.66Å; F133-F179 HydrophobicContact CE1-CD2 3.66Å; F133-F179 HydrophobicContact CE1-CE1 4.31Å; F133-F179 AromaticContact CE1-CE2 3.82Å; F133-F179 HydrophobicContact CE1-CE2 3.82Å; F133-F179 AromaticContact CE1-CG 3.85Å; F133-F179 HydrophobicContact CE1-CG 3.85Å; F133-F179 HydrophobicContact CE1-CZ 4.14Å; F133-F179 HydrophobicContact CE2-CB 3.27Å; F133-F179 AromaticContact CE2-CD1 3.97Å; F133-F179 HydrophobicContact CE2-CD1 3.97Å; F133-F179 AromaticContact CE2-CD2 3.99Å; F133-F179 HydrophobicContact CE2-CD2 3.99Å; F133-F179 AromaticContact CE2-CG 3.48Å; F133-F179 HydrophobicContact CE2-CG 3.48Å; F133-F179 VanDerWaalsContact CE2-CG 3.48Å; F133-F179 HydrophobicContact CG-CB 4.37Å; F133-F179 HydrophobicContact CG-CD2 4.12Å; F133-F179 HydrophobicContact CG-CG 4.41Å; F133-F179 HydrophobicContact CZ-CB 3.77Å; F133-F179 AromaticContact CZ-CD1 3.56Å; F133-F179 HydrophobicContact CZ-CD1 3.56Å; F133-F179 AromaticContact CZ-CD2 3.73Å; F133-F179 HydrophobicContact CZ-CD2 3.73Å; F133-F179 HydrophobicContact CZ-CE1 4.03Å; F133-F179 HydrophobicContact CZ-CE2 4.18Å; F133-F179 AromaticContact CZ-CG 3.39Å; F133-F179 HydrophobicContact CZ-CG 3.39Å; F133-F179 HydrophobicContact CZ-CZ 4.32Å; A176-F179 PolarHBondContact O-N 2.91Å; S177-F179 PolarHBondContact O-N 3.26Å; F179-I181 PolarHBondContact O-N 3.25Å; F179-P182 WeakPolarHBondContact O-CD 3.19Å; F179-A183 WeakPolarHBondContact O-CB 3.33Å; F179-A183 PolarHBondContact O-N 3.27Å; F179-F220 HydrophobicContact CE1-CB 4.45Å; F179-F220 HydrophobicContact CE1-CD2 4.09Å; F179-F220 HydrophobicContact CE1-CG 4.46Å; F179-F220 HydrophobicContact CE2-CB 4.4Å; F179-F220 HydrophobicContact CZ-CB 3.85Å; F179-F220 HydrophobicContact CZ-CD1 4.44Å; F179-F220 AromaticContact CZ-CD2 3.75Å; F179-F220 HydrophobicContact CZ-CD2 3.75Å; F179-F220 HydrophobicContact CZ-CE2 4.43Å; F179-F220 AromaticContact CZ-CG 3.77Å; F179-F220 HydrophobicContact CZ-CG 3.77Å
180	G	90.2	Very high	91.2	Very high	0 Å²	0	50.6 Å²	50.6	0%	0	29%	0.288	C	S	.	.	H	α-helix	trans	-67	-34.9	-177.2	0	0	0	0	0	114.3	S126 A176 M184	S126-G180 PolarHBondContact OG-O 3.42Å; S126-G180 VanDerWaalsContact OG-O 3.04Å; A176-G180 PolarHBondContact O-N 2.97Å; G180-M184 PolarHBondContact O-N 3.47Å
181	I	93	Very high	89.6	Confident	94 Å²	94	51.1 Å²	51.1	48%	0.482	29%	0.287	S	S	.	.	H	α-helix	trans	-70.5	-51	176.7	-65	172.3	0	0	0	110.7	S177 F179 A183 M184 V185	S177-I181 WeakPolarHBondContact O-CB 3.43Å; S177-I181 WeakPolarHBondContact O-CG1 3.24Å; S177-I181 PolarHBondContact O-N 2.9Å; F179-I181 PolarHBondContact O-N 3.25Å; I181-A183 VanDerWaalsContact C-N 3.29Å; I181-A183 PolarHBondContact O-N 2.85Å; I181-M184 WeakPolarHBondContact O-CB 3.35Å; I181-M184 PolarHBondContact O-N 3.45Å; I181-M184 VanDerWaalsContact O-N 3.12Å; I181-V185 PolarHBondContact O-N 2.87Å
182	P	90.6	Very high	87.6	Confident	54 Å²	54	53.1 Å²	53.1	35%	0.351	29%	0.289	S	S	.	.	H	α-helix	trans	-55.4	-43.3	172.8	-29.5	37.2	0	0	0	113	V178 F179 M184 V185 M186	V178-P182 VanDerWaalsContact O-CD 3.25Å; V178-P182 WeakPolarHBondContact O-CD 3.35Å; V178-P182 VanDerWaalsContact O-CG 3.23Å; V178-P182 WeakPolarHBondContact O-CG 3.29Å; F179-P182 WeakPolarHBondContact O-CD 3.19Å; P182-M184 VanDerWaalsContact C-N 3.29Å; P182-M184 PolarHBondContact O-N 3.04Å; P182-V185 PolarHBondContact O-N 3.19Å; P182-V185 VanDerWaalsContact O-N 3.12Å; P182-M186 HydrophobicContact CB-CE 4.02Å; P182-M186 WeakPolarHBondContact O-CB 3.33Å; P182-M186 VanDerWaalsContact O-CG 3.29Å; P182-M186 WeakPolarHBondContact O-CG 3.3Å; P182-M186 PolarHBondContact O-N 2.82Å
183	A	87.9	Confident	85.7	Confident	0 Å²	0	60.1 Å²	60.1	0%	0	33%	0.327	C	S	.	.	H	α-helix	trans	-59.5	-38.9	176.9	0	0	0	0	0	112.3	I125 Y129 F179 I181 G187	I125-A183 HydrophobicContact CG2-CB 4.17Å; Y129-A183 HydrophobicContact CD1-CB 3.83Å; Y129-A183 HydrophobicContact CD2-CB 3.98Å; Y129-A183 HydrophobicContact CE1-CB 4.36Å; Y129-A183 HydrophobicContact CE2-CB 4.48Å; Y129-A183 HydrophobicContact CG-CB 3.64Å; F179-A183 WeakPolarHBondContact O-CB 3.33Å; F179-A183 PolarHBondContact O-N 3.27Å; I181-A183 VanDerWaalsContact C-N 3.29Å; I181-A183 PolarHBondContact O-N 2.85Å; A183-G187 PolarHBondContact O-N 3.36Å
184	M	90.3	Very high	83.8	Confident	78 Å²	78	64.9 Å²	64.9	38%	0.384	36%	0.357	S	S	.	.	H	α-helix	trans	-64.2	-40.6	174.3	-169.4	-175.9	-69.6	0	0	112.7	K122 S126 G180 I181 P182	K122-M184 HydrophobicContact CB-CG 4.27Å; K122-M184 WeakPolarHBondContact CG-O 3.36Å; S126-M184 WeakPolarHBondContact OG-CE 3.3Å; G180-M184 PolarHBondContact O-N 3.47Å; I181-M184 WeakPolarHBondContact O-CB 3.35Å; I181-M184 PolarHBondContact O-N 3.45Å; I181-M184 VanDerWaalsContact O-N 3.12Å; P182-M184 VanDerWaalsContact C-N 3.29Å; P182-M184 PolarHBondContact O-N 3.04Å
185	V	91.5	Very high	82.1	Confident	105 Å²	105	67.7 Å²	67.7	64%	0.636	36%	0.36	S	S	*	.	H	α-helix	trans	-69.4	-44	179.5	174.8	0	0	0	0	110.5	K122 I181 P182	K122-V185 PolarHBondContact NZ-O 2.89Å; I181-V185 PolarHBondContact O-N 2.87Å; P182-V185 PolarHBondContact O-N 3.19Å; P182-V185 VanDerWaalsContact O-N 3.12Å
186	M	87.1	Confident	81.2	Confident	42 Å²	42	66.1 Å²	66.1	21%	0.207	35%	0.351	C	S	.	.	H	α-helix	trans	-78.4	-23.5	-177.3	-64.5	-175.8	-58.1	0	0	113.8	P182 S188 I200 K201 L202 F213	P182-M186 HydrophobicContact CB-CE 4.02Å; P182-M186 WeakPolarHBondContact O-CB 3.33Å; P182-M186 VanDerWaalsContact O-CG 3.29Å; P182-M186 WeakPolarHBondContact O-CG 3.3Å; P182-M186 PolarHBondContact O-N 2.82Å; M186-S188 PolarHBondContact O-N 3.46Å; M186-I200 HydrophobicContact CB-CG2 3.89Å; M186-I200 HydrophobicContact CE-CG2 4.23Å; M186-K201 PolarHBondContact O-N 3.31Å; M186-L202 HydrophobicContact SD-CD2 4.08Å; M186-F213 HydrophobicContact CE-CD2 4.28Å; M186-F213 HydrophobicContact CE-CE2 3.71Å; M186-F213 HydrophobicContact CE-CZ 4.2Å
187	G	86.8	Confident	80.3	Confident	0 Å²	0	69 Å²	69	0%	0	37%	0.367	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-60.8	133.4	175.6	0	0	0	0	0	111.4	K122 A183 L199	K122-G187 WeakPolarHBondContact CE-O 3.38Å; K122-G187 WeakPolarHBondContact CG-O 3.4Å; K122-G187 PolarHBondContact NZ-O 3.08Å; A183-G187 PolarHBondContact O-N 3.36Å; G187-L199 WeakPolarHBondContact CA-O 3.46Å
188	S	85.6	Confident	79.8	Confident	16 Å²	16	68.6 Å²	68.6	11%	0.112	36%	0.364	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-145.7	143.8	-179.8	-161.6	0	0	0	0	111	N118 M186 E190 L199	N118-S188 WeakPolarHBondContact OD1-CA 3.47Å; M186-S188 PolarHBondContact O-N 3.46Å; S188-E190 WeakPolarHBondContact OG-CG 3.2Å; S188-L199 PolarHBondContact N-O 3.02Å; S188-L199 PolarHBondContact O-N 2.81Å; S188-L199 VanDerWaalsContact O-N 3.09Å
189	A	82.7	Confident	79.3	Confident	12 Å²	12	69.4 Å²	69.4	10%	0.099	37%	0.365	C	S	.	.			trans	-124	58.5	167.6	0	0	0	0	0	110.2	W114 N118 C121 I196 D197 C198	W114-A189 HydrophobicContact CG-CB 4.3Å; N118-A189 PolarHBondContact OD1-N 3.4Å; N118-A189 VanDerWaalsContact OD1-N 3.08Å; C121-A189 HydrophobicContact CB-CB 3.66Å; A189-I196 HydrophobicContact CB-CG2 4.27Å; A189-D197 WeakPolarHBondContact CA-O 3.42Å; A189-C198 HydrophobicContact CB-CB 4.48Å
190	E	74.6	Confident	79.1	Confident	112 Å²	112	69.8 Å²	69.8	52%	0.523	37%	0.368	S	S	.	.			trans	-97.2	148.2	179	-75.4	174.6	-176.7	0	0	110.9	S188 E192	S188-E190 WeakPolarHBondContact OG-CG 3.2Å; E190-E192 PolarHBondContact O-N 3.46Å
191	N	63.2	Low	78.8	Confident	113 Å²	113	74.6 Å²	74.6	60%	0.604	39%	0.389	S	S	*	.			trans	-67.9	89.6	176.1	-84.5	-40.9	0	0	0	110.6	I196	N191-I196 WeakPolarHBondContact OD1-CG1 3.34Å
192	E	56	Low	78.4	Confident	116 Å²	116	71.2 Å²	71.2	54%	0.542	37%	0.371	S	S	.	.	B	Isolated β-bridge	trans	-96.9	117.7	158.6	-74.5	-173.4	178.1	0	0	107.5	E190 K201	E190-E192 PolarHBondContact O-N 3.46Å; E192-K201 IonicContact OE1-NZ 3.11Å; E192-K201 PolarHBondContact OE1-NZ 3.21Å
193	N	56.5	Low	78.2	Confident	155 Å²	155	71.8 Å²	71.8	83%	0.829	38%	0.375	S	S	*	.	T	Hydrogen-bonded Turn	trans	65.1	36.9	173.8	-51	-34.1	0	0	0	117.5	E195	N193-E195 PolarHBondContact O-N 3.45Å
194	N	55.8	Low	78	Confident	164 Å²	164	76.9 Å²	76.9	88%	0.877	41%	0.411	S	S	*	.	T	Hydrogen-bonded Turn	trans	70.3	6.8	175.8	-114.2	33.7	0	0	0	115.3
195	E	61.5	Low	77.9	Confident	119 Å²	119	77.1 Å²	77.1	56%	0.556	42%	0.418	S	S	*	.	B	Isolated β-bridge	trans	-112.7	134.5	171.2	-68.6	178.5	157.4	0	0	109.1	N193	N193-E195 PolarHBondContact O-N 3.45Å
196	I	76.1	Confident	77.5	Confident	54 Å²	54	75.6 Å²	75.6	28%	0.277	41%	0.409	S	S	.	.			trans	-104.9	97.2	176.4	-59.3	169.8	0	0	0	106.7	F113 W114 A189 N191	F113-I196 CarbonylContact C-O 3.22Å; F113-I196 WeakPolarHBondContact CA-O 3.45Å; F113-I196 WeakPolarHBondContact CB-O 3.26Å; W114-I196 HydrophobicContact CB-CG2 4.25Å; W114-I196 PolarHBondContact N-O 2.92Å; W114-I196 VanDerWaalsContact O-CG2 3.26Å; W114-I196 WeakPolarHBondContact O-CG2 3.44Å; A189-I196 HydrophobicContact CB-CG2 4.27Å; N191-I196 WeakPolarHBondContact OD1-CG1 3.34Å
197	D	77.4	Confident	77.3	Confident	61 Å²	61	80.9 Å²	80.9	33%	0.326	44%	0.438	S	S	.	.			trans	-109	143.3	175.3	-69.4	-25.6	0	0	0	111.1	A189 L199	A189-D197 WeakPolarHBondContact CA-O 3.42Å; D197-L199 HydrophobicContact CB-CD1 3.61Å; D197-L199 HydrophobicContact CB-CG 3.89Å; D197-L199 PolarHBondContact O-N 3.16Å
198	C	85.1	Confident	77.3	Confident	18 Å²	18	87.5 Å²	87.5	12%	0.122	46%	0.464	C	S	.	.			trans	-92.3	97.6	173.9	178.8	0	0	0	0	110.6	W114 C121 A189	W114-C198 HydrophobicContact CB-CB 3.89Å; W114-C198 HydrophobicContact CD2-CB 3.56Å; W114-C198 HydrophobicContact CE3-CB 3.66Å; W114-C198 HydrophobicContact CG-CB 3.66Å; W114-C198 HydrophobicContact CZ3-CB 4.41Å; C121-C198 WeakPolarHBondContact CA-SG 3.45Å; C121-C198 HydrophobicContact CB-CB 3.87Å; C121-C198 WeakPolarHBondContact CB-SG 3.22Å; C121-C198 WeakPolarHBondContact SG-CA 3.25Å; C121-C198 WeakPolarHBondContact SG-CB 3.47Å; C121-C198 CovalentContact SG-SG 2.03Å; C121-C198 PolarHBondContact SG-SG 3.29Å; A189-C198 HydrophobicContact CB-CB 4.48Å
199	L	83.8	Confident	77.4	Confident	109 Å²	109	91.7 Å²	91.7	57%	0.571	48%	0.477	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-134.2	165.1	-172.4	-61.7	166	0	0	0	111.7	G187 S188 D197	G187-L199 WeakPolarHBondContact CA-O 3.46Å; S188-L199 PolarHBondContact N-O 3.02Å; S188-L199 PolarHBondContact O-N 2.81Å; S188-L199 VanDerWaalsContact O-N 3.09Å; D197-L199 HydrophobicContact CB-CD1 3.61Å; D197-L199 HydrophobicContact CB-CG 3.89Å; D197-L199 PolarHBondContact O-N 3.16Å
200	I	84.8	Confident	77.3	Confident	43 Å²	43	93.8 Å²	93.8	22%	0.221	49%	0.487	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-82.3	118.1	169.8	-67.9	-177	0	0	0	108.7	I125 Y129 M186 L202 F213	I125-I200 HydrophobicContact CD1-CG1 4.32Å; I125-I200 HydrophobicContact CG2-CD1 4.04Å; I125-I200 HydrophobicContact CG2-CG1 3.87Å; Y129-I200 HydrophobicContact CD2-CD1 4.38Å; Y129-I200 HydrophobicContact CE1-CD1 4.31Å; Y129-I200 HydrophobicContact CE2-CD1 3.43Å; Y129-I200 VanDerWaalsContact CE2-CD1 3.43Å; Y129-I200 WeakPolarHBondContact OH-CD1 3.28Å; M186-I200 HydrophobicContact CB-CG2 3.89Å; M186-I200 HydrophobicContact CE-CG2 4.23Å; I200-L202 HydrophobicContact CG2-CD2 4.28Å; I200-L202 HydrophobicContact CG2-CG 4.25Å; I200-F213 HydrophobicContact CD1-CE1 3.94Å; I200-F213 HydrophobicContact CD1-CZ 3.89Å; I200-F213 HydrophobicContact CG2-CE1 4.46Å
201	K	85.4	Confident	77.8	Confident	102 Å²	102	89.9 Å²	89.9	44%	0.443	47%	0.471	S	S	.	.			trans	-92	107.5	174.3	-172.2	166.5	177.9	165.8	0	109.9	M186 E192	M186-K201 PolarHBondContact O-N 3.31Å; E192-K201 IonicContact OE1-NZ 3.11Å; E192-K201 PolarHBondContact OE1-NZ 3.21Å
202	L	84	Confident	79	Confident	22 Å²	22	86.6 Å²	86.6	12%	0.115	46%	0.455	C	S	.	.	P	Polyproline II helix	trans	-81.4	151.2	178.5	-71.3	166.5	0	0	0	111.8	M186 I200 W209 D210 F213	M186-L202 HydrophobicContact SD-CD2 4.08Å; I200-L202 HydrophobicContact CG2-CD2 4.28Å; I200-L202 HydrophobicContact CG2-CG 4.25Å; L202-W209 HydrophobicContact CB-CB 4.31Å; L202-D210 HydrophobicContact CD1-CB 3.76Å; L202-D210 WeakPolarHBondContact CD1-OD1 3.44Å; L202-F213 HydrophobicContact CD1-CB 4.37Å; L202-F213 HydrophobicContact CD2-CB 3.96Å; L202-F213 HydrophobicContact CD2-CD1 4.35Å; L202-F213 HydrophobicContact CD2-CD2 4.31Å; L202-F213 HydrophobicContact CD2-CG 3.96Å
203	P	86.3	Confident	80.5	Confident	66 Å²	66	83.1 Å²	83.1	43%	0.429	44%	0.438	S	S	.	.	P	Polyproline II helix	trans	-66.8	151	177.6	27.3	-32.8	0	0	0	111.6	P205 W209	P203-P205 CarbonylContact O-C 3.48Å; P203-W209 HydrophobicContact CG-CB 4.38Å; P203-W209 HydrophobicContact CG-CD2 4.09Å; P203-W209 HydrophobicContact CG-CG 3.85Å
204	S	84	Confident	81.9	Confident	108 Å²	108	75.9 Å²	75.9	76%	0.755	40%	0.4	S	S	*	.	S	Bend	trans	-70.7	140.2	172.7	-52.1	0	0	0	0	111
205	P	88.4	Confident	83.4	Confident	82 Å²	82	71.4 Å²	71.4	53%	0.532	38%	0.376	S	S	.	.	S	Bend	cis	-80.8	127.7	0.3	30.2	-31.4	0	0	0	113.2	P203 D207 Y208 W209	P203-P205 CarbonylContact O-C 3.48Å; P205-D207 PolarHBondContact O-N 3.35Å; P205-Y208 PolarHBondContact O-N 2.94Å; P205-W209 VanDerWaalsContact O-CD1 3.31Å; P205-W209 PolarHBondContact O-N 3.06Å
206	V	82.1	Confident	84.8	Confident	74 Å²	74	68 Å²	68	45%	0.448	36%	0.364	S	S	.	.	H	α-helix	trans	-63.7	-40.2	-174.3	179.8	0	0	0	0	111.7	Y208 W209 D210	V206-Y208 PolarHBondContact O-N 3.31Å; V206-W209 PolarHBondContact O-N 3.29Å; V206-W209 VanDerWaalsContact O-N 3.1Å; V206-D210 HydrophobicContact CG1-CB 4.31Å; V206-D210 VanDerWaalsContact O-CB 3.31Å; V206-D210 WeakPolarHBondContact O-CB 3.47Å; V206-D210 PolarHBondContact O-N 3.45Å
207	D	83.8	Confident	85.4	Confident	152 Å²	152	65.7 Å²	65.7	81%	0.813	35%	0.353	S	S	*	.	H	α-helix	trans	-57.2	-23	179.1	-57.1	-32.8	0	0	0	113.8	P205 P211	P205-D207 PolarHBondContact O-N 3.35Å; D207-P211 VanDerWaalsContact O-CD 3.3Å; D207-P211 WeakPolarHBondContact O-CD 3.5Å; D207-P211 VanDerWaalsContact O-CG 3.28Å; D207-P211 WeakPolarHBondContact O-CG 3.42Å
208	Y	86.7	Confident	86	Confident	140 Å²	140	64.3 Å²	64.3	55%	0.549	34%	0.344	S	S	.	.	H	α-helix	trans	-91.6	-46.6	174.8	179.7	-98.4	0	0	0	112	P205 V206 P211 V212	P205-Y208 PolarHBondContact O-N 2.94Å; V206-Y208 PolarHBondContact O-N 3.31Å; Y208-P211 WeakPolarHBondContact O-CG 3.45Å; Y208-V212 HydrophobicContact CD1-CG2 4.44Å; Y208-V212 HydrophobicContact CE1-CG2 4.09Å; Y208-V212 HydrophobicContact CE2-CG2 4.39Å; Y208-V212 WeakPolarHBondContact O-CG2 3.37Å; Y208-V212 PolarHBondContact O-N 3.42Å
209	W	87	Confident	86.3	Confident	103 Å²	103	66.9 Å²	66.9	39%	0.39	36%	0.356	S	S	.	.	H	α-helix	trans	-76.3	-27.2	-172.4	-74	109.2	0	0	0	113.7	L202 P203 P205 V206 V212 F213	L202-W209 HydrophobicContact CB-CB 4.31Å; P203-W209 HydrophobicContact CG-CB 4.38Å; P203-W209 HydrophobicContact CG-CD2 4.09Å; P203-W209 HydrophobicContact CG-CG 3.85Å; P205-W209 VanDerWaalsContact O-CD1 3.31Å; P205-W209 PolarHBondContact O-N 3.06Å; V206-W209 PolarHBondContact O-N 3.29Å; V206-W209 VanDerWaalsContact O-N 3.1Å; W209-V212 HydrophobicContact CE3-CG1 4.31Å; W209-V212 HydrophobicContact CZ3-CG1 4.41Å; W209-F213 WeakPolarHBondContact O-CB 3.31Å; W209-F213 PolarHBondContact O-N 3.37Å
210	D	81.4	Confident	86.6	Confident	56 Å²	56	65.9 Å²	65.9	30%	0.299	35%	0.348	S	S	.	.	H	α-helix	trans	-64.7	-54.6	178.2	-166.9	50.1	0	0	0	113.4	L202 V206 V212 F213 G214 C285	L202-D210 HydrophobicContact CD1-CB 3.76Å; L202-D210 WeakPolarHBondContact CD1-OD1 3.44Å; V206-D210 HydrophobicContact CG1-CB 4.31Å; V206-D210 VanDerWaalsContact O-CB 3.31Å; V206-D210 WeakPolarHBondContact O-CB 3.47Å; V206-D210 PolarHBondContact O-N 3.45Å; D210-V212 VanDerWaalsContact C-N 3.32Å; D210-V212 PolarHBondContact O-N 3.14Å; D210-F213 PolarHBondContact O-N 2.97Å; D210-G214 PolarHBondContact O-N 3.43Å; D210-C285 WeakPolarHBondContact OD2-CA 3.27Å
211	P	85.4	Confident	86.8	Confident	30 Å²	30	63.9 Å²	63.9	20%	0.195	34%	0.337	C	S	.	.	H	α-helix	trans	-61.3	-39.6	173.5	19.9	-30.4	0	0	0	112.4	D207 Y208 F213 G214 I215 C285 L286	D207-P211 VanDerWaalsContact O-CD 3.3Å; D207-P211 WeakPolarHBondContact O-CD 3.5Å; D207-P211 VanDerWaalsContact O-CG 3.28Å; D207-P211 WeakPolarHBondContact O-CG 3.42Å; Y208-P211 WeakPolarHBondContact O-CG 3.45Å; P211-F213 PolarHBondContact O-N 3.38Å; P211-G214 PolarHBondContact O-N 2.96Å; P211-I215 VanDerWaalsContact O-CB 3.27Å; P211-I215 WeakPolarHBondContact O-CB 3.06Å; P211-I215 WeakPolarHBondContact O-CD1 3.42Å; P211-I215 WeakPolarHBondContact O-CG1 3.47Å; P211-I215 PolarHBondContact O-N 3.39Å; P211-C285 WeakPolarHBondContact CA-O 2.71Å; P211-C285 VanDerWaalsContact CB-O 3.29Å; P211-C285 WeakPolarHBondContact CB-O 3.43Å; P211-L286 HydrophobicContact CB-CD2 4.47Å
212	V	88.6	Confident	86.9	Confident	45 Å²	45	59.5 Å²	59.5	27%	0.273	32%	0.318	S	S	.	.	H	α-helix	trans	-61.4	-47.7	179.1	169.7	0	0	0	0	110.6	Y208 W209 D210 C216	Y208-V212 HydrophobicContact CD1-CG2 4.44Å; Y208-V212 HydrophobicContact CE1-CG2 4.09Å; Y208-V212 HydrophobicContact CE2-CG2 4.39Å; Y208-V212 WeakPolarHBondContact O-CG2 3.37Å; Y208-V212 PolarHBondContact O-N 3.42Å; W209-V212 HydrophobicContact CE3-CG1 4.31Å; W209-V212 HydrophobicContact CZ3-CG1 4.41Å; D210-V212 VanDerWaalsContact C-N 3.32Å; D210-V212 PolarHBondContact O-N 3.14Å; V212-C216 WeakPolarHBondContact O-CB 3.36Å; V212-C216 PolarHBondContact O-N 3.21Å; V212-C216 PolarHBondContact O-SG 3.13Å
213	F	86.2	Confident	87.2	Confident	42 Å²	42	61.4 Å²	61.4	18%	0.184	33%	0.327	C	S	.	.	H	α-helix	trans	-64.5	-47.8	179.3	-178	-103.5	0	0	0	111.5	Y129 M186 I200 L202 W209 D210 P211 I215 C216 V217	Y129-F213 HydrophobicContact CE1-CE1 4.18Å; Y129-F213 AromaticContact CE1-CZ 3.56Å; Y129-F213 HydrophobicContact CE1-CZ 3.56Å; Y129-F213 AromaticContact CZ-CZ 3.78Å; Y129-F213 WeakPolarHBondContact OH-CE1 3.21Å; Y129-F213 WeakPolarHBondContact OH-CZ 3.47Å; M186-F213 HydrophobicContact CE-CD2 4.28Å; M186-F213 HydrophobicContact CE-CE2 3.71Å; M186-F213 HydrophobicContact CE-CZ 4.2Å; I200-F213 HydrophobicContact CD1-CE1 3.94Å; I200-F213 HydrophobicContact CD1-CZ 3.89Å; I200-F213 HydrophobicContact CG2-CE1 4.46Å; L202-F213 HydrophobicContact CD1-CB 4.37Å; L202-F213 HydrophobicContact CD2-CB 3.96Å; L202-F213 HydrophobicContact CD2-CD1 4.35Å; L202-F213 HydrophobicContact CD2-CD2 4.31Å; L202-F213 HydrophobicContact CD2-CG 3.96Å; W209-F213 WeakPolarHBondContact O-CB 3.31Å; W209-F213 PolarHBondContact O-N 3.37Å; D210-F213 PolarHBondContact O-N 2.97Å; P211-F213 PolarHBondContact O-N 3.38Å; F213-I215 PolarHBondContact O-N 2.91Å; F213-C216 PolarHBondContact O-N 3Å; F213-V217 HydrophobicContact CD1-CG2 4.37Å; F213-V217 HydrophobicContact CE1-CG2 4.05Å; F213-V217 HydrophobicContact CE2-CG2 4.28Å; F213-V217 HydrophobicContact CZ-CG2 4Å; F213-V217 WeakPolarHBondContact O-CG2 3.18Å; F213-V217 PolarHBondContact O-N 3.32Å
214	G	85.5	Confident	87.6	Confident	3 Å²	3	61.6 Å²	61.6	3%	0.031	32%	0.324	C	S	.	.	H	α-helix	trans	-58.5	-45	176.5	0	0	0	0	0	113.2	D210 P211 V217 F218	D210-G214 PolarHBondContact O-N 3.43Å; P211-G214 PolarHBondContact O-N 2.96Å; G214-V217 PolarHBondContact O-N 3.4Å; G214-F218 WeakPolarHBondContact O-CB 3.41Å; G214-F218 PolarHBondContact O-N 2.63Å
215	I	88.7	Confident	87.9	Confident	70 Å²	70	56.6 Å²	56.6	36%	0.359	29%	0.289	S	S	.	.	H	α-helix	trans	-64	-44.5	176.4	-69.7	165	0	0	0	110.8	P211 F213 F218 L219 L282 L286	P211-I215 VanDerWaalsContact O-CB 3.27Å; P211-I215 WeakPolarHBondContact O-CB 3.06Å; P211-I215 WeakPolarHBondContact O-CD1 3.42Å; P211-I215 WeakPolarHBondContact O-CG1 3.47Å; P211-I215 PolarHBondContact O-N 3.39Å; F213-I215 PolarHBondContact O-N 2.91Å; I215-F218 PolarHBondContact O-N 2.86Å; I215-L219 HydrophobicContact CG2-CD1 3.77Å; I215-L219 HydrophobicContact CG2-CG 4.2Å; I215-L219 WeakPolarHBondContact O-CB 3.38Å; I215-L219 VanDerWaalsContact O-CG 3.26Å; I215-L219 WeakPolarHBondContact O-CG 3.1Å; I215-L219 PolarHBondContact O-N 2.94Å; I215-L282 HydrophobicContact CG1-CD1 3.87Å; I215-L286 HydrophobicContact CD1-CD2 4.36Å
216	C	90.6	Very high	87.9	Confident	47 Å²	47	53.6 Å²	53.6	32%	0.318	27%	0.269	S	S	.	.	H	α-helix	trans	-60.3	-47.4	177	-76.3	0	0	0	0	111.4	V212 F213 L219 F220	V212-C216 WeakPolarHBondContact O-CB 3.36Å; V212-C216 PolarHBondContact O-N 3.21Å; V212-C216 PolarHBondContact O-SG 3.13Å; F213-C216 PolarHBondContact O-N 3Å; C216-L219 PolarHBondContact O-N 3.41Å; C216-F220 VanDerWaalsContact O-CD2 3.22Å; C216-F220 WeakPolarHBondContact O-CD2 3.31Å; C216-F220 PolarHBondContact O-N 3.49Å
217	V	88.2	Confident	88.4	Confident	7 Å²	7	55 Å²	55	4%	0.042	27%	0.273	C	S	.	.	H	α-helix	trans	-58.4	-50.7	176.1	169.1	0	0	0	0	110.3	Y129 M132 F213 G214 L219 F220 S221	Y129-V217 HydrophobicContact CE1-CG2 4.04Å; M132-V217 HydrophobicContact CE-CG1 3.51Å; M132-V217 HydrophobicContact SD-CG1 4.03Å; F213-V217 HydrophobicContact CD1-CG2 4.37Å; F213-V217 HydrophobicContact CE1-CG2 4.05Å; F213-V217 HydrophobicContact CE2-CG2 4.28Å; F213-V217 HydrophobicContact CZ-CG2 4Å; F213-V217 WeakPolarHBondContact O-CG2 3.18Å; F213-V217 PolarHBondContact O-N 3.32Å; G214-V217 PolarHBondContact O-N 3.4Å; V217-L219 VanDerWaalsContact C-N 3.35Å; V217-L219 PolarHBondContact O-N 2.76Å; V217-F220 PolarHBondContact O-N 3.19Å; V217-S221 WeakPolarHBondContact O-CA 3.46Å; V217-S221 WeakPolarHBondContact O-CB 3.48Å; V217-S221 PolarHBondContact O-N 3.33Å; V217-S221 PolarHBondContact O-OG 3.44Å
218	F	89.2	Confident	88.7	Confident	32 Å²	32	50.9 Å²	50.9	14%	0.14	25%	0.251	C	S	.	.	H	α-helix	trans	-57.5	-44.4	178.9	179	-102.3	0	0	0	112.8	G214 I215 F222 M223 Q278 L282	G214-F218 WeakPolarHBondContact O-CB 3.41Å; G214-F218 PolarHBondContact O-N 2.63Å; I215-F218 PolarHBondContact O-N 2.86Å; F218-F222 HydrophobicContact CD2-CD1 4.31Å; F218-F222 AromaticContact CE2-CD1 3.74Å; F218-F222 HydrophobicContact CE2-CD1 3.74Å; F218-F222 HydrophobicContact CE2-CE1 4.33Å; F218-F222 HydrophobicContact CZ-CD1 4.16Å; F218-F222 WeakPolarHBondContact O-CA 3.22Å; F218-F222 WeakPolarHBondContact O-CB 3.13Å; F218-F222 PolarHBondContact O-N 3.26Å; F218-F222 VanDerWaalsContact O-N 3.14Å; F218-M223 HydrophobicContact CD1-CG 3.76Å; F218-M223 HydrophobicContact CE1-CE 4.33Å; F218-M223 HydrophobicContact CE1-CG 3.19Å; F218-M223 HydrophobicContact CE1-SD 3.99Å; F218-M223 HydrophobicContact CZ-CE 3.82Å; F218-M223 HydrophobicContact CZ-CG 3.65Å; F218-M223 HydrophobicContact CZ-SD 4.07Å; F218-M223 PolarHBondContact O-N 3.04Å; F218-Q278 HydrophobicContact CD2-CB 4.02Å; F218-Q278 HydrophobicContact CE2-CB 4.2Å; F218-L282 HydrophobicContact CB-CD1 4.49Å; F218-L282 HydrophobicContact CD1-CD2 4.05Å; F218-L282 HydrophobicContact CD2-CB 4.48Å; F218-L282 HydrophobicContact CD2-CD2 4.14Å; F218-L282 HydrophobicContact CE1-CD2 4.06Å; F218-L282 HydrophobicContact CE2-CD2 4.18Å; F218-L282 HydrophobicContact CG-CD2 4.09Å; F218-L282 HydrophobicContact CZ-CD2 4.13Å
219	L	92.3	Very high	88.8	Confident	71 Å²	71	44.5 Å²	44.5	37%	0.372	23%	0.226	S	C	.	.	I	π-helix	trans	-66.2	-51.3	-179	-72.9	175.7	0	0	0	112.4	I215 C216 V217 M223 I224	I215-L219 HydrophobicContact CG2-CD1 3.77Å; I215-L219 HydrophobicContact CG2-CG 4.2Å; I215-L219 WeakPolarHBondContact O-CB 3.38Å; I215-L219 VanDerWaalsContact O-CG 3.26Å; I215-L219 WeakPolarHBondContact O-CG 3.1Å; I215-L219 PolarHBondContact O-N 2.94Å; C216-L219 PolarHBondContact O-N 3.41Å; V217-L219 VanDerWaalsContact C-N 3.35Å; V217-L219 PolarHBondContact O-N 2.76Å; L219-M223 HydrophobicContact CD2-CB 4.22Å; L219-M223 HydrophobicContact CD2-CG 4.41Å; L219-M223 PolarHBondContact O-N 3.41Å; L219-I224 WeakPolarHBondContact O-CB 3.36Å; L219-I224 WeakPolarHBondContact O-CG1 3.25Å; L219-I224 PolarHBondContact O-N 3.34Å
220	F	90.4	Very high	88.8	Confident	89 Å²	89	42.6 Å²	42.6	39%	0.39	23%	0.226	S	C	.	.	I	π-helix	trans	-82.1	-33.1	-172.4	-72	-70.9	0	0	0	113.4	F133 F179 C216 V217 I224 P225	F133-F220 HydrophobicContact CE1-CB 3.88Å; F179-F220 HydrophobicContact CE1-CB 4.45Å; F179-F220 HydrophobicContact CE1-CD2 4.09Å; F179-F220 HydrophobicContact CE1-CG 4.46Å; F179-F220 HydrophobicContact CE2-CB 4.4Å; F179-F220 HydrophobicContact CZ-CB 3.85Å; F179-F220 HydrophobicContact CZ-CD1 4.44Å; F179-F220 AromaticContact CZ-CD2 3.75Å; F179-F220 HydrophobicContact CZ-CD2 3.75Å; F179-F220 HydrophobicContact CZ-CE2 4.43Å; F179-F220 AromaticContact CZ-CG 3.77Å; F179-F220 HydrophobicContact CZ-CG 3.77Å; C216-F220 VanDerWaalsContact O-CD2 3.22Å; C216-F220 WeakPolarHBondContact O-CD2 3.31Å; C216-F220 PolarHBondContact O-N 3.49Å; V217-F220 PolarHBondContact O-N 3.19Å; F220-I224 HydrophobicContact CD1-CD1 3.85Å; F220-I224 HydrophobicContact CE1-CD1 3.92Å; F220-P225 VanDerWaalsContact O-CD 3.3Å; F220-P225 WeakPolarHBondContact O-CD 3.46Å; F220-P225 WeakPolarHBondContact O-CG 3.33Å
221	S	88	Confident	89.2	Confident	0 Å²	0	44.7 Å²	44.7	0%	0	24%	0.236	C	C	.	.	I	π-helix	trans	-88.7	-16.5	-179.8	76.2	0	0	0	0	113.8	T136 V217 Q278	T136-S221 WeakPolarHBondContact CG2-O 3.38Å; T136-S221 PolarHBondContact OG1-O 2.99Å; V217-S221 WeakPolarHBondContact O-CA 3.46Å; V217-S221 WeakPolarHBondContact O-CB 3.48Å; V217-S221 PolarHBondContact O-N 3.33Å; V217-S221 PolarHBondContact O-OG 3.44Å; S221-Q278 PolarHBondContact OG-NE2 3.11Å
222	F	88.3	Confident	89.3	Confident	10 Å²	10	44 Å²	44	4%	0.044	23%	0.232	C	C	.	.	I	π-helix	trans	-133.8	-65.7	-175.5	-173.4	-110.2	0	0	0	113.4	F218 P225 V226 F270 W274 T275 Q278	F218-F222 HydrophobicContact CD2-CD1 4.31Å; F218-F222 AromaticContact CE2-CD1 3.74Å; F218-F222 HydrophobicContact CE2-CD1 3.74Å; F218-F222 HydrophobicContact CE2-CE1 4.33Å; F218-F222 HydrophobicContact CZ-CD1 4.16Å; F218-F222 WeakPolarHBondContact O-CA 3.22Å; F218-F222 WeakPolarHBondContact O-CB 3.13Å; F218-F222 PolarHBondContact O-N 3.26Å; F218-F222 VanDerWaalsContact O-N 3.14Å; F222-P225 WeakPolarHBondContact O-CD 3.37Å; F222-V226 HydrophobicContact CD2-CG2 4.01Å; F222-V226 HydrophobicContact CE2-CG2 3.83Å; F222-V226 HydrophobicContact CG-CG2 4.48Å; F222-V226 HydrophobicContact CZ-CG2 4.16Å; F222-V226 WeakPolarHBondContact O-CB 3.27Å; F222-V226 WeakPolarHBondContact O-CG2 3.19Å; F222-V226 PolarHBondContact O-N 3.36Å; F222-F270 HydrophobicContact CD2-CE1 4.23Å; F222-F270 HydrophobicContact CE2-CE1 4.4Å; F222-W274 HydrophobicContact CD2-CB 4.17Å; F222-W274 HydrophobicContact CE2-CB 4.17Å; F222-T275 HydrophobicContact CZ-CG2 4.38Å; F222-T275 WeakPolarHBondContact CZ-OG1 3.34Å; F222-Q278 HydrophobicContact CB-CG 4.01Å; F222-Q278 HydrophobicContact CD1-CB 4.38Å; F222-Q278 HydrophobicContact CD2-CG 4.18Å; F222-Q278 HydrophobicContact CG-CB 4.31Å; F222-Q278 HydrophobicContact CG-CG 4.02Å
223	M	91.2	Very high	88.9	Confident	62 Å²	62	42.7 Å²	42.7	31%	0.305	22%	0.222	S	C	.	.	I	π-helix	trans	-61.2	-55.6	-171.1	-77.3	-74.8	104.9	0	0	114.2	F218 L219 V226 L227	F218-M223 HydrophobicContact CD1-CG 3.76Å; F218-M223 HydrophobicContact CE1-CE 4.33Å; F218-M223 HydrophobicContact CE1-CG 3.19Å; F218-M223 HydrophobicContact CE1-SD 3.99Å; F218-M223 HydrophobicContact CZ-CE 3.82Å; F218-M223 HydrophobicContact CZ-CG 3.65Å; F218-M223 HydrophobicContact CZ-SD 4.07Å; F218-M223 PolarHBondContact O-N 3.04Å; L219-M223 HydrophobicContact CD2-CB 4.22Å; L219-M223 HydrophobicContact CD2-CG 4.41Å; L219-M223 PolarHBondContact O-N 3.41Å; M223-V226 PolarHBondContact O-N 3.32Å; M223-L227 WeakPolarHBondContact O-CB 3.03Å; M223-L227 VanDerWaalsContact O-CG 3.25Å; M223-L227 WeakPolarHBondContact O-CG 3.15Å; M223-L227 PolarHBondContact O-N 2.92Å
224	I	92.8	Very high	88.8	Confident	71 Å²	71	43 Å²	43	36%	0.364	23%	0.23	S	C	.	.	H	α-helix	trans	-59.9	-48.9	-178.4	-67.8	167	0	0	0	110.8	L219 F220 V226 L227 I228	L219-I224 WeakPolarHBondContact O-CB 3.36Å; L219-I224 WeakPolarHBondContact O-CG1 3.25Å; L219-I224 PolarHBondContact O-N 3.34Å; F220-I224 HydrophobicContact CD1-CD1 3.85Å; F220-I224 HydrophobicContact CE1-CD1 3.92Å; I224-V226 PolarHBondContact O-N 3.23Å; I224-L227 PolarHBondContact O-N 3.34Å; I224-I228 HydrophobicContact CG2-CD1 3.82Å; I224-I228 HydrophobicContact CG2-CG1 4.48Å; I224-I228 WeakPolarHBondContact O-CG1 3.3Å; I224-I228 PolarHBondContact O-N 2.97Å
225	P	91.3	Very high	88.9	Confident	2 Å²	2	46.2 Å²	46.2	1%	0.013	25%	0.245	C	C	.	.	H	α-helix	trans	-54.8	-49.4	173.2	-30.2	37.3	0	0	0	114	T136 F220 F222 L227 I228 I229	T136-P225 HydrophobicContact CG2-CB 3.17Å; T136-P225 HydrophobicContact CG2-CG 3.27Å; F220-P225 VanDerWaalsContact O-CD 3.3Å; F220-P225 WeakPolarHBondContact O-CD 3.46Å; F220-P225 WeakPolarHBondContact O-CG 3.33Å; F222-P225 WeakPolarHBondContact O-CD 3.37Å; P225-L227 VanDerWaalsContact C-N 3.3Å; P225-L227 PolarHBondContact O-N 2.92Å; P225-I228 PolarHBondContact O-N 3.39Å; P225-I229 VanDerWaalsContact O-CB 3.26Å; P225-I229 WeakPolarHBondContact O-CB 3.48Å; P225-I229 WeakPolarHBondContact O-CG1 3.17Å; P225-I229 PolarHBondContact O-N 2.92Å
226	V	89.2	Confident	88.5	Confident	20 Å²	20	42.9 Å²	42.9	12%	0.121	23%	0.229	C	C	.	.	H	α-helix	trans	-60.9	-40.2	179.5	169.1	0	0	0	0	111.1	F222 M223 I224 T230 F270 I271	F222-V226 HydrophobicContact CD2-CG2 4.01Å; F222-V226 HydrophobicContact CE2-CG2 3.83Å; F222-V226 HydrophobicContact CG-CG2 4.48Å; F222-V226 HydrophobicContact CZ-CG2 4.16Å; F222-V226 WeakPolarHBondContact O-CB 3.27Å; F222-V226 WeakPolarHBondContact O-CG2 3.19Å; F222-V226 PolarHBondContact O-N 3.36Å; M223-V226 PolarHBondContact O-N 3.32Å; I224-V226 PolarHBondContact O-N 3.23Å; V226-T230 WeakPolarHBondContact O-CB 3.46Å; V226-T230 PolarHBondContact O-N 2.83Å; V226-T230 PolarHBondContact O-OG1 3.44Å; V226-F270 HydrophobicContact CG2-CD1 4.32Å; V226-F270 HydrophobicContact CG2-CE1 3.88Å; V226-I271 HydrophobicContact CG1-CD1 4.28Å; V226-I271 HydrophobicContact CG2-CG1 4.36Å
227	L	91.4	Very high	88	Confident	102 Å²	102	43 Å²	43	53%	0.534	23%	0.225	S	C	.	.	H	α-helix	trans	-62.6	-49.3	175.8	-71.9	170.8	0	0	0	111.7	M223 I224 P225 I229 T230 I231	M223-L227 WeakPolarHBondContact O-CB 3.03Å; M223-L227 VanDerWaalsContact O-CG 3.25Å; M223-L227 WeakPolarHBondContact O-CG 3.15Å; M223-L227 PolarHBondContact O-N 2.92Å; I224-L227 PolarHBondContact O-N 3.34Å; P225-L227 VanDerWaalsContact C-N 3.3Å; P225-L227 PolarHBondContact O-N 2.92Å; L227-I229 PolarHBondContact O-N 3.5Å; L227-T230 PolarHBondContact O-N 3.33Å; L227-I231 WeakPolarHBondContact O-CB 3.1Å; L227-I231 VanDerWaalsContact O-CG1 3.27Å; L227-I231 WeakPolarHBondContact O-CG1 3.17Å; L227-I231 PolarHBondContact O-N 2.95Å
228	I	91.4	Very high	87.7	Confident	66 Å²	66	50.7 Å²	50.7	34%	0.338	25%	0.254	S	S	.	.	H	α-helix	trans	-60.3	-48.9	178.6	-65.6	167.1	0	0	0	110.2	T140 V144 I224 P225 T230 I231 C232	T140-I228 HydrophobicContact CG2-CB 3.92Å; T140-I228 HydrophobicContact CG2-CD1 4.25Å; T140-I228 HydrophobicContact CG2-CG2 3.52Å; V144-I228 HydrophobicContact CG2-CG2 4.42Å; I224-I228 HydrophobicContact CG2-CD1 3.82Å; I224-I228 HydrophobicContact CG2-CG1 4.48Å; I224-I228 WeakPolarHBondContact O-CG1 3.3Å; I224-I228 PolarHBondContact O-N 2.97Å; P225-I228 PolarHBondContact O-N 3.39Å; I228-T230 VanDerWaalsContact C-N 3.32Å; I228-T230 PolarHBondContact O-N 3.27Å; I228-I231 PolarHBondContact O-N 3.43Å; I228-C232 WeakPolarHBondContact O-CB 3.37Å; I228-C232 PolarHBondContact O-N 3.14Å; I228-C232 PolarHBondContact O-SG 3.29Å; I228-C232 VanDerWaalsContact O-SG 3.34Å
229	I	88.3	Confident	87.3	Confident	6 Å²	6	55.1 Å²	55.1	3%	0.031	27%	0.269	C	S	.	.	H	α-helix	trans	-54.5	-49.9	176.9	-74.3	172.4	0	0	0	110.2	T140 P225 L227 I231 C232 Y233 V267	T140-I229 HydrophobicContact CG2-CG1 4.43Å; P225-I229 VanDerWaalsContact O-CB 3.26Å; P225-I229 WeakPolarHBondContact O-CB 3.48Å; P225-I229 WeakPolarHBondContact O-CG1 3.17Å; P225-I229 PolarHBondContact O-N 2.92Å; L227-I229 PolarHBondContact O-N 3.5Å; I229-I231 PolarHBondContact O-N 3.28Å; I229-C232 PolarHBondContact O-N 3.48Å; I229-Y233 HydrophobicContact CG2-CD2 3.58Å; I229-Y233 HydrophobicContact CG2-CE2 3.61Å; I229-Y233 WeakPolarHBondContact O-CB 3.34Å; I229-Y233 WeakPolarHBondContact O-CD2 3.35Å; I229-Y233 PolarHBondContact O-N 3.34Å; I229-V267 HydrophobicContact CG2-CB 4.46Å; I229-V267 HydrophobicContact CG2-CG1 4.03Å; I229-V267 HydrophobicContact CG2-CG2 3.59Å
230	T	86.6	Confident	86.5	Confident	64 Å²	64	52.6 Å²	52.6	39%	0.393	26%	0.256	S	S	.	.	H	α-helix	trans	-63.2	-42.4	-178.9	-59.8	0	0	0	0	111.8	V226 L227 I228 S234	V226-T230 WeakPolarHBondContact O-CB 3.46Å; V226-T230 PolarHBondContact O-N 2.83Å; V226-T230 PolarHBondContact O-OG1 3.44Å; L227-T230 PolarHBondContact O-N 3.33Å; I228-T230 VanDerWaalsContact C-N 3.32Å; I228-T230 PolarHBondContact O-N 3.27Å; T230-S234 VanDerWaalsContact O-CB 3.23Å; T230-S234 WeakPolarHBondContact O-CB 3.35Å; T230-S234 PolarHBondContact O-N 3.34Å; T230-S234 PolarHBondContact O-OG 3.45Å
231	I	89.4	Confident	85.6	Confident	99 Å²	99	55.1 Å²	55.1	51%	0.508	27%	0.267	S	S	.	.	H	α-helix	trans	-65.2	-52	177.3	-69.3	165.8	0	0	0	110.4	L227 I228 I229 Y233 S234 L235	L227-I231 WeakPolarHBondContact O-CB 3.1Å; L227-I231 VanDerWaalsContact O-CG1 3.27Å; L227-I231 WeakPolarHBondContact O-CG1 3.17Å; L227-I231 PolarHBondContact O-N 2.95Å; I228-I231 PolarHBondContact O-N 3.43Å; I229-I231 PolarHBondContact O-N 3.28Å; I231-Y233 PolarHBondContact O-N 3.44Å; I231-S234 PolarHBondContact O-N 3.34Å; I231-L235 HydrophobicContact CG2-CD1 3.99Å; I231-L235 HydrophobicContact CG2-CG 4.41Å; I231-L235 VanDerWaalsContact O-CG 3.32Å; I231-L235 WeakPolarHBondContact O-CG 3.31Å; I231-L235 PolarHBondContact O-N 3.34Å
232	C	87.5	Confident	84.9	Confident	16 Å²	16	60.2 Å²	60.2	11%	0.108	29%	0.294	C	S	.	.	H	α-helix	trans	-54.3	-44.5	179.2	-74.9	0	0	0	0	111.2	I228 I229 M236	I228-C232 WeakPolarHBondContact O-CB 3.37Å; I228-C232 PolarHBondContact O-N 3.14Å; I228-C232 PolarHBondContact O-SG 3.29Å; I228-C232 VanDerWaalsContact O-SG 3.34Å; I229-C232 PolarHBondContact O-N 3.48Å; C232-M236 WeakPolarHBondContact O-CB 3.13Å; C232-M236 PolarHBondContact O-N 3.06Å
233	Y	80.9	Confident	84	Confident	18 Å²	18	62.3 Å²	62.3	7%	0.071	31%	0.308	C	S	.	.	H	α-helix	trans	-76	-34.6	-179.7	-70.5	-48.7	0	0	0	113.9	S143 I229 I231 L235 M236 I237 V263 V267	S143-Y233 WeakPolarHBondContact CA-OH 3.48Å; S143-Y233 WeakPolarHBondContact CB-OH 3.24Å; S143-Y233 WeakPolarHBondContact OG-CE2 3.26Å; S143-Y233 PolarHBondContact OG-OH 3.46Å; I229-Y233 HydrophobicContact CG2-CD2 3.58Å; I229-Y233 HydrophobicContact CG2-CE2 3.61Å; I229-Y233 WeakPolarHBondContact O-CB 3.34Å; I229-Y233 WeakPolarHBondContact O-CD2 3.35Å; I229-Y233 PolarHBondContact O-N 3.34Å; I231-Y233 PolarHBondContact O-N 3.44Å; Y233-L235 VanDerWaalsContact C-N 3.33Å; Y233-L235 PolarHBondContact O-N 2.95Å; Y233-M236 HydrophobicContact CD1-CE 3.6Å; Y233-M236 HydrophobicContact CD1-SD 3.94Å; Y233-M236 HydrophobicContact CE1-CE 4.08Å; Y233-M236 HydrophobicContact CE1-SD 4.18Å; Y233-M236 WeakPolarHBondContact O-CB 3.4Å; Y233-M236 PolarHBondContact O-N 3.45Å; Y233-I237 WeakPolarHBondContact O-CB 3.36Å; Y233-I237 VanDerWaalsContact O-CG1 3.25Å; Y233-I237 WeakPolarHBondContact O-CG1 3.13Å; Y233-I237 PolarHBondContact O-N 3Å; Y233-V263 HydrophobicContact CD1-CG1 3.31Å; Y233-V263 HydrophobicContact CD2-CG1 4.1Å; Y233-V263 HydrophobicContact CE1-CB 4.16Å; Y233-V263 HydrophobicContact CE1-CG1 3.03Å; Y233-V263 HydrophobicContact CE1-CG2 4.07Å; Y233-V263 HydrophobicContact CE2-CG1 3.82Å; Y233-V263 HydrophobicContact CG-CG1 3.86Å; Y233-V267 HydrophobicContact CD2-CG2 3.58Å; Y233-V267 HydrophobicContact CE2-CG2 3.35Å
234	S	84.3	Confident	82.5	Confident	49 Å²	49	66.3 Å²	66.3	34%	0.343	32%	0.32	S	S	.	.	H	α-helix	trans	-60.1	-45.1	172.3	-64.8	0	0	0	0	111.3	T230 I231 I237 R238	T230-S234 VanDerWaalsContact O-CB 3.23Å; T230-S234 WeakPolarHBondContact O-CB 3.35Å; T230-S234 PolarHBondContact O-N 3.34Å; T230-S234 PolarHBondContact O-OG 3.45Å; I231-S234 PolarHBondContact O-N 3.34Å; S234-I237 PolarHBondContact O-N 2.86Å; S234-R238 WeakPolarHBondContact O-CB 3.2Å; S234-R238 VanDerWaalsContact O-CG 3.3Å; S234-R238 WeakPolarHBondContact O-CG 3.42Å; S234-R238 PolarHBondContact O-N 3.36Å
235	L	86.3	Confident	80.8	Confident	69 Å²	69	69 Å²	69	36%	0.361	34%	0.339	S	S	.	.	H	α-helix	trans	-65.1	-41.6	176	-65.3	175.9	0	0	0	111.9	Y147 I231 Y233 R238 R239	Y147-L235 HydrophobicContact CD2-CB 4.15Å; Y147-L235 HydrophobicContact CE2-CB 3.65Å; Y147-L235 HydrophobicContact CE2-CD1 4.16Å; I231-L235 HydrophobicContact CG2-CD1 3.99Å; I231-L235 HydrophobicContact CG2-CG 4.41Å; I231-L235 VanDerWaalsContact O-CG 3.32Å; I231-L235 WeakPolarHBondContact O-CG 3.31Å; I231-L235 PolarHBondContact O-N 3.34Å; Y233-L235 VanDerWaalsContact C-N 3.33Å; Y233-L235 PolarHBondContact O-N 2.95Å; L235-R238 PolarHBondContact O-N 2.84Å; L235-R239 WeakPolarHBondContact O-CB 3.45Å; L235-R239 PolarHBondContact O-N 2.67Å
236	M	82	Confident	79.3	Confident	1 Å²	1	76.2 Å²	76.2	1%	0.005	38%	0.377	C	S	.	.	H	α-helix	trans	-59.3	-49.1	174.9	-171.4	-174.4	78.7	0	0	111.4	I150 C232 Y233 R238 R239 L240 V263	I150-M236 HydrophobicContact CB-CG 4.25Å; I150-M236 HydrophobicContact CD1-CG 3.86Å; I150-M236 HydrophobicContact CD1-SD 3.47Å; I150-M236 WeakPolarHBondContact CD1-SD 3.32Å; I150-M236 HydrophobicContact CG2-CG 4.02Å; C232-M236 WeakPolarHBondContact O-CB 3.13Å; C232-M236 PolarHBondContact O-N 3.06Å; Y233-M236 HydrophobicContact CD1-CE 3.6Å; Y233-M236 HydrophobicContact CD1-SD 3.94Å; Y233-M236 HydrophobicContact CE1-CE 4.08Å; Y233-M236 HydrophobicContact CE1-SD 4.18Å; Y233-M236 WeakPolarHBondContact O-CB 3.4Å; Y233-M236 PolarHBondContact O-N 3.45Å; M236-R238 PolarHBondContact O-N 2.78Å; M236-R239 PolarHBondContact O-N 3.3Å; M236-L240 HydrophobicContact CE-CD1 4.31Å; M236-L240 HydrophobicContact CG-CD1 3.98Å; M236-L240 WeakPolarHBondContact O-CB 3.38Å; M236-L240 WeakPolarHBondContact O-CG 3.21Å; M236-L240 PolarHBondContact O-N 3.02Å; M236-V263 HydrophobicContact CE-CB 4.49Å; M236-V263 HydrophobicContact CE-CG1 4.02Å
237	I	78.6	Confident	77.8	Confident	49 Å²	49	78 Å²	78	25%	0.251	39%	0.39	S	S	.	.	H	α-helix	trans	-62.2	-43.5	179.2	-68.9	165.3	0	0	0	110.9	Y233 S234 R239 L240 K241 T260 L264	Y233-I237 WeakPolarHBondContact O-CB 3.36Å; Y233-I237 VanDerWaalsContact O-CG1 3.25Å; Y233-I237 WeakPolarHBondContact O-CG1 3.13Å; Y233-I237 PolarHBondContact O-N 3Å; S234-I237 PolarHBondContact O-N 2.86Å; I237-R239 PolarHBondContact O-N 3.08Å; I237-L240 PolarHBondContact O-N 2.97Å; I237-K241 HydrophobicContact CG2-CD 4.33Å; I237-K241 HydrophobicContact CG2-CG 4.49Å; I237-K241 WeakPolarHBondContact O-CG 3.29Å; I237-K241 PolarHBondContact O-N 3.36Å; I237-T260 HydrophobicContact CG1-CG2 4.14Å; I237-L264 HydrophobicContact CD1-CD2 4.37Å
238	R	81.9	Confident	76.2	Confident	168 Å²	168	77.2 Å²	77.2	63%	0.634	41%	0.407	S	S	*	.	H	α-helix	trans	-58.7	-46.7	175.5	-75.4	175.9	-179.3	175.5	1.3	111.3	S234 L235 M236 L240 K241 N242	S234-R238 WeakPolarHBondContact O-CB 3.2Å; S234-R238 VanDerWaalsContact O-CG 3.3Å; S234-R238 WeakPolarHBondContact O-CG 3.42Å; S234-R238 PolarHBondContact O-N 3.36Å; L235-R238 PolarHBondContact O-N 2.84Å; M236-R238 PolarHBondContact O-N 2.78Å; R238-L240 PolarHBondContact O-N 2.55Å; R238-K241 PolarHBondContact O-N 2.84Å; R238-N242 VanDerWaalsContact O-CG 3.23Å; R238-N242 PolarHBondContact O-N 3.06Å; R238-N242 PolarHBondContact O-OD1 2.69Å
239	R	81.9	Confident	74.8	Confident	125 Å²	125	77 Å²	77	47%	0.472	41%	0.411	S	S	.	.	H	α-helix	trans	-61.1	-44.2	177.1	-177.7	61.2	173	-178.6	0.5	111.8	C151 L235 M236 I237 N242 V243	C151-R239 HydrophobicContact CB-CG 4.41Å; L235-R239 WeakPolarHBondContact O-CB 3.45Å; L235-R239 PolarHBondContact O-N 2.67Å; M236-R239 PolarHBondContact O-N 3.3Å; I237-R239 PolarHBondContact O-N 3.08Å; R239-N242 PolarHBondContact O-N 3.39Å; R239-V243 HydrophobicContact CG-CG2 4.39Å; R239-V243 VanDerWaalsContact O-CG2 3.29Å; R239-V243 WeakPolarHBondContact O-CG2 3.33Å; R239-V243 PolarHBondContact O-N 2.92Å
240	L	74.6	Confident	73.5	Confident	19 Å²	19	85.4 Å²	85.4	10%	0.099	45%	0.447	C	S	.	.	H	α-helix	trans	-63.3	-42.1	179.1	-69.5	169.3	0	0	0	112.1	I150 M236 I237 R238 R244 L256 T260	I150-L240 HydrophobicContact CG2-CD2 3.63Å; I150-L240 HydrophobicContact CG2-CG 3.94Å; M236-L240 HydrophobicContact CE-CD1 4.31Å; M236-L240 HydrophobicContact CG-CD1 3.98Å; M236-L240 WeakPolarHBondContact O-CB 3.38Å; M236-L240 WeakPolarHBondContact O-CG 3.21Å; M236-L240 PolarHBondContact O-N 3.02Å; I237-L240 PolarHBondContact O-N 2.97Å; R238-L240 PolarHBondContact O-N 2.55Å; L240-R244 VanDerWaalsContact O-CB 3.31Å; L240-R244 WeakPolarHBondContact O-CB 3.31Å; L240-R244 PolarHBondContact O-N 2.88Å; L240-L256 HydrophobicContact CD2-CB 4.25Å; L240-L256 HydrophobicContact CD2-CD2 3.16Å; L240-L256 HydrophobicContact CD2-CG 3.46Å; L240-L256 VanDerWaalsContact CD2-CG 3.46Å; L240-T260 WeakPolarHBondContact CD1-OG1 3.3Å
241	K	72.4	Confident	72.2	Confident	141 Å²	141	90 Å²	90	61%	0.613	46%	0.464	S	S	*	.	H	α-helix	trans	-61.7	-44.9	174.1	-74.7	-177	178.3	-174.7	0	111.6	I237 R238 R244 V245	I237-K241 HydrophobicContact CG2-CD 4.33Å; I237-K241 HydrophobicContact CG2-CG 4.49Å; I237-K241 WeakPolarHBondContact O-CG 3.29Å; I237-K241 PolarHBondContact O-N 3.36Å; R238-K241 PolarHBondContact O-N 2.84Å; K241-R244 WeakPolarHBondContact O-CB 3.46Å; K241-R244 PolarHBondContact O-N 3.41Å; K241-V245 PolarHBondContact O-N 2.89Å
242	N	73.5	Confident	70.7	Confident	107 Å²	107	91.7 Å²	91.7	57%	0.572	47%	0.468	S	S	*	.	H	α-helix	trans	-67.9	-39.1	-178.4	-66.7	-2.5	0	0	0	112.5	R238 R239 R244 V245	R238-N242 VanDerWaalsContact O-CG 3.23Å; R238-N242 PolarHBondContact O-N 3.06Å; R238-N242 PolarHBondContact O-OD1 2.69Å; R239-N242 PolarHBondContact O-N 3.39Å; N242-R244 VanDerWaalsContact C-N 3.34Å; N242-V245 PolarHBondContact O-N 3.13Å
243	V	68.6	Low	69.5	Low	55 Å²	55	92.5 Å²	92.5	33%	0.333	47%	0.471	S	S	.	.	H	α-helix	trans	-71	-31.1	176.9	175.7	0	0	0	0	111.6	R239 V245 L246 S247	R239-V243 HydrophobicContact CG-CG2 4.39Å; R239-V243 VanDerWaalsContact O-CG2 3.29Å; R239-V243 WeakPolarHBondContact O-CG2 3.33Å; R239-V243 PolarHBondContact O-N 2.92Å; V243-V245 VanDerWaalsContact C-N 3.27Å; V243-V245 PolarHBondContact O-N 3.32Å; V243-L246 PolarHBondContact O-N 3.3Å; V243-L246 VanDerWaalsContact O-N 3.08Å; V243-S247 PolarHBondContact O-N 3.08Å
244	R	59.5	Low	68.8	Low	146 Å²	146	100.5 Å²	100.5	55%	0.551	50%	0.501	S	S	*	.	H	α-helix	trans	-63.9	-30.7	175.9	-173.5	177.2	-179.7	-158.4	-4.8	112.9	L240 K241 N242 L246 D253	L240-R244 VanDerWaalsContact O-CB 3.31Å; L240-R244 WeakPolarHBondContact O-CB 3.31Å; L240-R244 PolarHBondContact O-N 2.88Å; K241-R244 WeakPolarHBondContact O-CB 3.46Å; K241-R244 PolarHBondContact O-N 3.41Å; N242-R244 VanDerWaalsContact C-N 3.34Å; R244-L246 VanDerWaalsContact C-N 3.28Å; R244-D253 IonicContact CZ-OD2 2.77Å; R244-D253 IonicContact NE-OD1 3.16Å; R244-D253 IonicContact NE-OD2 3.58Å; R244-D253 PolarHBondContact NE-OD2 3.39Å
245	V	57.1	Low	67.8	Low	126 Å²	126	102.6 Å²	102.6	76%	0.764	51%	0.509	S	S	*	.	H	α-helix	trans	-69.6	-28	174	178.6	0	0	0	0	111.4	K241 N242 V243	K241-V245 PolarHBondContact O-N 2.89Å; N242-V245 PolarHBondContact O-N 3.13Å; V243-V245 VanDerWaalsContact C-N 3.27Å; V243-V245 PolarHBondContact O-N 3.32Å
246	L	59	Low	66.8	Low	155 Å²	155	101.6 Å²	101.6	81%	0.812	50%	0.503	S	S	*	.	H	α-helix	trans	-95.1	-25.8	-176.3	-101.6	76.8	0	0	0	115.2	V243 R244	V243-L246 PolarHBondContact O-N 3.3Å; V243-L246 VanDerWaalsContact O-N 3.08Å; R244-L246 VanDerWaalsContact C-N 3.28Å
247	S	58.5	Low	66	Low	58 Å²	58	106.7 Å²	106.7	41%	0.406	52%	0.522	S	S	.	.			trans	-123.1	88.6	-166.6	-155.8	0	0	0	0	111.2	V243 S249	V243-S247 PolarHBondContact O-N 3.08Å; S247-S249 PolarHBondContact O-N 3.04Å
248	G	57.7	Low	65.5	Low	85 Å²	85	107.9 Å²	107.9	88%	0.876	52%	0.524	S	S	*	.			trans	-66.4	20.5	-175.4	0	0	0	0	0	117.5	K250	G248-K250 PolarHBondContact O-N 3Å
249	S	63.2	Low	64.7	Low	61 Å²	61	102.7 Å²	102.7	43%	0.427	51%	0.508	S	S	.	.			trans	-84.4	110.5	179	179.1	0	0	0	0	112	S247 E251 D253	S247-S249 PolarHBondContact O-N 3.04Å; S249-E251 VanDerWaalsContact C-N 3.33Å; S249-E251 PolarHBondContact O-N 3.46Å; S249-D253 WeakPolarHBondContact O-CB 3.26Å; S249-D253 PolarHBondContact O-N 2.9Å
250	K	59.6	Low	63.9	Low	183 Å²	183	98 Å²	98	80%	0.796	49%	0.493	S	S	*	.	H	α-helix	trans	-63.1	-30.3	-175.9	-67.7	-178.1	178.9	177.3	0	114.4	G248 R254	G248-K250 PolarHBondContact O-N 3Å; K250-R254 PolarHBondContact O-N 2.95Å
251	E	59.3	Low	63.6	Low	159 Å²	159	105 Å²	105	74%	0.743	52%	0.518	S	S	*	.	H	α-helix	trans	-79	-45.4	-175.6	-170.5	175.5	-177.9	0	0	112.4	S249 D253 R254 N255	S249-E251 VanDerWaalsContact C-N 3.33Å; S249-E251 PolarHBondContact O-N 3.46Å; E251-D253 PolarHBondContact O-N 3.45Å; E251-R254 PolarHBondContact O-N 3.35Å; E251-N255 PolarHBondContact O-N 3.44Å
252	K	59.1	Low	63.4	Low	135 Å²	135	100.1 Å²	100.1	59%	0.587	50%	0.498	S	S	*	.	H	α-helix	trans	-60.4	-36.5	173.5	-166.8	172.6	-178.3	175.7	0	111.2	L256	K252-L256 HydrophobicContact CG-CD1 4.45Å; K252-L256 WeakPolarHBondContact O-CD1 3.46Å; K252-L256 PolarHBondContact O-N 3.34Å; K252-L256 VanDerWaalsContact O-N 3.11Å
253	D	61.5	Low	62.9	Low	33 Å²	33	95.5 Å²	95.5	18%	0.176	47%	0.474	C	S	.	.	H	α-helix	trans	-68.4	-35	178.2	-164.6	24.5	0	0	0	112.8	R244 S249 E251 R257	R244-D253 IonicContact CZ-OD2 2.77Å; R244-D253 IonicContact NE-OD1 3.16Å; R244-D253 IonicContact NE-OD2 3.58Å; R244-D253 PolarHBondContact NE-OD2 3.39Å; S249-D253 WeakPolarHBondContact O-CB 3.26Å; S249-D253 PolarHBondContact O-N 2.9Å; E251-D253 PolarHBondContact O-N 3.45Å; D253-R257 VanDerWaalsContact CG-CZ 3.44Å; D253-R257 PolarHBondContact O-N 2.91Å; D253-R257 IonicContact OD1-CZ 2.78Å; D253-R257 IonicContact OD1-NH1 2.67Å; D253-R257 PolarHBondContact OD1-NH1 3.4Å; D253-R257 IonicContact OD1-NH2 3.94Å; D253-R257 IonicContact OD2-CZ 3.58Å; D253-R257 IonicContact OD2-NH1 2.87Å; D253-R257 PolarHBondContact OD2-NH1 3.37Å; D253-R257 IonicContact OD2-NH2 3.79Å; D253-R257 PolarHBondContact OD2-NH2 2.96Å
254	R	66.6	Low	63	Low	186 Å²	186	97.4 Å²	97.4	70%	0.702	48%	0.482	S	S	*	.	H	α-helix	trans	-67.8	-43.7	175	-178.5	176.9	161.1	-174.8	-6.2	112.2	K250 E251 R257 R258	K250-R254 PolarHBondContact O-N 2.95Å; E251-R254 PolarHBondContact O-N 3.35Å; R254-R257 PolarHBondContact O-N 3.2Å; R254-R258 PolarHBondContact O-N 3.39Å
255	N	63.2	Low	63.6	Low	94 Å²	94	93.2 Å²	93.2	50%	0.503	47%	0.472	S	S	.	.	H	α-helix	trans	-65.1	-40.7	176.1	-89.2	2.8	0	0	0	111.9	E251 R258 I259	E251-N255 PolarHBondContact O-N 3.44Å; N255-R258 PolarHBondContact O-N 2.64Å; N255-I259 WeakPolarHBondContact O-CD1 3.31Å; N255-I259 VanDerWaalsContact O-CG1 3.26Å; N255-I259 WeakPolarHBondContact O-CG1 3.49Å; N255-I259 PolarHBondContact O-N 2.88Å
256	L	64.4	Low	64.3	Low	48 Å²	48	88.6 Å²	88.6	25%	0.251	44%	0.444	S	S	.	.	H	α-helix	trans	-61.5	-43.5	174.7	-102.3	63	0	0	0	112.8	L240 K252 I259 T260	L240-L256 HydrophobicContact CD2-CB 4.25Å; L240-L256 HydrophobicContact CD2-CD2 3.16Å; L240-L256 HydrophobicContact CD2-CG 3.46Å; L240-L256 VanDerWaalsContact CD2-CG 3.46Å; K252-L256 HydrophobicContact CG-CD1 4.45Å; K252-L256 WeakPolarHBondContact O-CD1 3.46Å; K252-L256 PolarHBondContact O-N 3.34Å; K252-L256 VanDerWaalsContact O-N 3.11Å; L256-I259 PolarHBondContact O-N 3.29Å; L256-T260 WeakPolarHBondContact O-CB 3.49Å; L256-T260 PolarHBondContact O-N 3.17Å; L256-T260 PolarHBondContact O-OG1 2.65Å
257	R	65.6	Low	64.8	Low	107 Å²	107	82.3 Å²	82.3	40%	0.404	41%	0.412	S	S	.	.	H	α-helix	trans	-61.9	-42.5	175	-86.8	-170.1	-81.7	-78.4	3.3	112.5	D253 R254 T260 R261	D253-R257 VanDerWaalsContact CG-CZ 3.44Å; D253-R257 PolarHBondContact O-N 2.91Å; D253-R257 IonicContact OD1-CZ 2.78Å; D253-R257 IonicContact OD1-NH1 2.67Å; D253-R257 PolarHBondContact OD1-NH1 3.4Å; D253-R257 IonicContact OD1-NH2 3.94Å; D253-R257 IonicContact OD2-CZ 3.58Å; D253-R257 IonicContact OD2-NH1 2.87Å; D253-R257 PolarHBondContact OD2-NH1 3.37Å; D253-R257 IonicContact OD2-NH2 3.79Å; D253-R257 PolarHBondContact OD2-NH2 2.96Å; R254-R257 PolarHBondContact O-N 3.2Å; R257-T260 PolarHBondContact O-N 2.93Å; R257-R261 WeakPolarHBondContact O-CB 3.44Å; R257-R261 PolarHBondContact O-N 2.99Å
258	R	68.1	Low	65.8	Low	74 Å²	74	81.7 Å²	81.7	28%	0.279	41%	0.411	S	S	.	.	H	α-helix	trans	-60.4	-45.8	176.8	-176.8	-176.2	-178.4	155	5.5	111.4	R254 N255 R261 M262 E322	R254-R258 PolarHBondContact O-N 3.39Å; N255-R258 PolarHBondContact O-N 2.64Å; R258-R261 PolarHBondContact O-N 3.38Å; R258-M262 WeakPolarHBondContact O-CB 3.3Å; R258-M262 PolarHBondContact O-N 2.95Å; R258-E322 IonicContact CZ-OE1 2.77Å; R258-E322 VanDerWaalsContact NH1-CD 3.25Å; R258-E322 IonicContact NH1-OE1 3.27Å; R258-E322 PolarHBondContact NH1-OE1 2.98Å; R258-E322 IonicContact NH1-OE2 3.42Å; R258-E322 IonicContact NH2-OE1 3.5Å; R258-E322 PolarHBondContact NH2-OE1 3.3Å
259	I	64.9	Low	66.9	Low	59 Å²	59	79 Å²	79	30%	0.303	38%	0.377	S	S	.	.	H	α-helix	trans	-63.3	-44.5	177.5	-65.9	164	0	0	0	110.5	I150 N255 L256 R261 M262 V263	I150-I259 HydrophobicContact CD1-CG2 4.38Å; N255-I259 WeakPolarHBondContact O-CD1 3.31Å; N255-I259 VanDerWaalsContact O-CG1 3.26Å; N255-I259 WeakPolarHBondContact O-CG1 3.49Å; N255-I259 PolarHBondContact O-N 2.88Å; L256-I259 PolarHBondContact O-N 3.29Å; I259-R261 PolarHBondContact O-N 3.39Å; I259-M262 WeakPolarHBondContact O-CB 3.46Å; I259-M262 PolarHBondContact O-N 3.4Å; I259-V263 WeakPolarHBondContact O-CB 3.37Å; I259-V263 VanDerWaalsContact O-CG2 3.24Å; I259-V263 WeakPolarHBondContact O-CG2 3.41Å; I259-V263 PolarHBondContact O-N 3.4Å
260	T	65.4	Low	67.6	Low	26 Å²	26	76.3 Å²	76.3	16%	0.16	36%	0.358	C	S	.	.	H	α-helix	trans	-62.3	-42.9	178	-51.3	0	0	0	0	111.9	I237 L240 L256 R257 V263 L264	I237-T260 HydrophobicContact CG1-CG2 4.14Å; L240-T260 WeakPolarHBondContact CD1-OG1 3.3Å; L256-T260 WeakPolarHBondContact O-CB 3.49Å; L256-T260 PolarHBondContact O-N 3.17Å; L256-T260 PolarHBondContact O-OG1 2.65Å; R257-T260 PolarHBondContact O-N 2.93Å; T260-V263 PolarHBondContact O-N 2.98Å; T260-L264 HydrophobicContact CG2-CD1 4.42Å; T260-L264 WeakPolarHBondContact O-CG 3.3Å; T260-L264 PolarHBondContact O-N 3.27Å
261	R	68.9	Low	68.8	Low	167 Å²	167	70.2 Å²	70.2	63%	0.63	33%	0.333	S	S	*	.	H	α-helix	trans	-66.1	-45.4	177.2	-173.2	-179.3	68.4	-166.7	3.3	111.8	R257 R258 I259 V263 L264 V265	R257-R261 WeakPolarHBondContact O-CB 3.44Å; R257-R261 PolarHBondContact O-N 2.99Å; R258-R261 PolarHBondContact O-N 3.38Å; I259-R261 PolarHBondContact O-N 3.39Å; R261-V263 PolarHBondContact O-N 3.4Å; R261-L264 PolarHBondContact O-N 2.98Å; R261-V265 VanDerWaalsContact O-CG2 3.3Å; R261-V265 WeakPolarHBondContact O-CG2 3.24Å; R261-V265 PolarHBondContact O-N 3.09Å; R261-V265 VanDerWaalsContact O-N 3.11Å
262	M	67.6	Low	70.1	Confident	38 Å²	38	67.9 Å²	67.9	19%	0.187	33%	0.325	C	S	.	.	H	α-helix	trans	-52.9	-45.6	174.4	168.3	177.9	-174.3	0	0	110.9	R258 I259 V265 V266 L320	R258-M262 WeakPolarHBondContact O-CB 3.3Å; R258-M262 PolarHBondContact O-N 2.95Å; I259-M262 WeakPolarHBondContact O-CB 3.46Å; I259-M262 PolarHBondContact O-N 3.4Å; M262-V265 PolarHBondContact O-N 3.21Å; M262-V266 WeakPolarHBondContact O-CG2 3.48Å; M262-V266 PolarHBondContact O-N 3.26Å; M262-L320 HydrophobicContact CB-CB 4.27Å; M262-L320 HydrophobicContact CB-CD1 4.27Å; M262-L320 HydrophobicContact CB-CD2 3.96Å; M262-L320 HydrophobicContact CB-CG 4.37Å; M262-L320 HydrophobicContact CE-CB 3.61Å; M262-L320 HydrophobicContact CE-CD1 4.32Å; M262-L320 HydrophobicContact CG-CB 3.62Å; M262-L320 HydrophobicContact CG-CD1 3.61Å; M262-L320 HydrophobicContact CG-CD2 4.1Å; M262-L320 HydrophobicContact CG-CG 3.94Å; M262-L320 HydrophobicContact SD-CB 3.52Å; M262-L320 VanDerWaalsContact SD-CB 3.52Å; M262-L320 HydrophobicContact SD-CG 4.48Å
263	V	63.5	Low	71.4	Confident	10 Å²	10	61.7 Å²	61.7	6%	0.061	30%	0.298	C	S	.	.	H	α-helix	trans	-66.3	-46.8	-178.9	157.4	0	0	0	0	112.8	Y233 M236 I259 T260 R261 V265 V266 V267	Y233-V263 HydrophobicContact CD1-CG1 3.31Å; Y233-V263 HydrophobicContact CD2-CG1 4.1Å; Y233-V263 HydrophobicContact CE1-CB 4.16Å; Y233-V263 HydrophobicContact CE1-CG1 3.03Å; Y233-V263 HydrophobicContact CE1-CG2 4.07Å; Y233-V263 HydrophobicContact CE2-CG1 3.82Å; Y233-V263 HydrophobicContact CG-CG1 3.86Å; M236-V263 HydrophobicContact CE-CB 4.49Å; M236-V263 HydrophobicContact CE-CG1 4.02Å; I259-V263 WeakPolarHBondContact O-CB 3.37Å; I259-V263 VanDerWaalsContact O-CG2 3.24Å; I259-V263 WeakPolarHBondContact O-CG2 3.41Å; I259-V263 PolarHBondContact O-N 3.4Å; T260-V263 PolarHBondContact O-N 2.98Å; R261-V263 PolarHBondContact O-N 3.4Å; V263-V265 PolarHBondContact O-N 3.1Å; V263-V266 PolarHBondContact O-N 2.95Å; V263-V266 VanDerWaalsContact O-N 3.17Å; V263-V267 PolarHBondContact O-N 2.88Å; V263-V267 VanDerWaalsContact O-N 3.12Å
264	L	69.4	Low	72.5	Confident	95 Å²	95	61.2 Å²	61.2	50%	0.497	29%	0.294	S	S	.	.	H	α-helix	trans	-60.4	-36.9	177.8	-74.2	172.2	0	0	0	111.7	I237 T260 R261 V267 A268	I237-L264 HydrophobicContact CD1-CD2 4.37Å; T260-L264 HydrophobicContact CG2-CD1 4.42Å; T260-L264 WeakPolarHBondContact O-CG 3.3Å; T260-L264 PolarHBondContact O-N 3.27Å; R261-L264 PolarHBondContact O-N 2.98Å; L264-V267 PolarHBondContact O-N 3.31Å; L264-A268 VanDerWaalsContact O-CB 3.3Å; L264-A268 WeakPolarHBondContact O-CB 3.46Å; L264-A268 PolarHBondContact O-N 2.92Å
265	V	73.6	Confident	73.5	Confident	59 Å²	59	54 Å²	54	36%	0.358	27%	0.27	S	S	.	.	H	α-helix	trans	-63.8	-44.8	175.7	172.2	0	0	0	0	111	R261 M262 V263 V267 A268 V269 L316	R261-V265 VanDerWaalsContact O-CG2 3.3Å; R261-V265 WeakPolarHBondContact O-CG2 3.24Å; R261-V265 PolarHBondContact O-N 3.09Å; R261-V265 VanDerWaalsContact O-N 3.11Å; M262-V265 PolarHBondContact O-N 3.21Å; V263-V265 PolarHBondContact O-N 3.1Å; V265-V267 PolarHBondContact O-N 2.83Å; V265-A268 PolarHBondContact O-N 2.84Å; V265-V269 HydrophobicContact CG1-CG2 4.27Å; V265-V269 WeakPolarHBondContact O-CB 3.42Å; V265-V269 VanDerWaalsContact O-CG2 3.24Å; V265-V269 WeakPolarHBondContact O-CG2 3.3Å; V265-V269 PolarHBondContact O-N 3.47Å; V265-L316 HydrophobicContact CG1-CD2 3.79Å
266	V	70.1	Confident	74.6	Confident	29 Å²	29	51.5 Å²	51.5	18%	0.176	26%	0.26	C	S	.	.	H	α-helix	trans	-62.1	-42.5	178.9	173.6	0	0	0	0	111.6	L139 M262 V263 V269 F270 L316	L139-V266 HydrophobicContact CD2-CG1 4.03Å; M262-V266 WeakPolarHBondContact O-CG2 3.48Å; M262-V266 PolarHBondContact O-N 3.26Å; V263-V266 PolarHBondContact O-N 2.95Å; V263-V266 VanDerWaalsContact O-N 3.17Å; V266-V269 PolarHBondContact O-N 3.32Å; V266-F270 PolarHBondContact O-N 2.85Å; V266-L316 HydrophobicContact CG2-CD1 4.35Å
267	V	71.4	Confident	75.6	Confident	23 Å²	23	50.3 Å²	50.3	14%	0.139	25%	0.254	C	S	.	.	H	α-helix	trans	-65.9	-44.7	177.1	177.8	0	0	0	0	111.4	I229 Y233 V263 L264 V265 V269 F270 I271	I229-V267 HydrophobicContact CG2-CB 4.46Å; I229-V267 HydrophobicContact CG2-CG1 4.03Å; I229-V267 HydrophobicContact CG2-CG2 3.59Å; Y233-V267 HydrophobicContact CD2-CG2 3.58Å; Y233-V267 HydrophobicContact CE2-CG2 3.35Å; V263-V267 PolarHBondContact O-N 2.88Å; V263-V267 VanDerWaalsContact O-N 3.12Å; L264-V267 PolarHBondContact O-N 3.31Å; V265-V267 PolarHBondContact O-N 2.83Å; V267-V269 VanDerWaalsContact C-N 3.34Å; V267-V269 PolarHBondContact O-N 2.88Å; V267-F270 PolarHBondContact O-N 2.85Å; V267-I271 HydrophobicContact CG1-CD1 3.75Å; V267-I271 HydrophobicContact CG1-CG1 4.38Å; V267-I271 WeakPolarHBondContact O-CG1 3.34Å; V267-I271 PolarHBondContact O-N 2.9Å
268	A	78.6	Confident	76.5	Confident	45 Å²	45	45.7 Å²	45.7	37%	0.372	24%	0.236	S	C	.	.	H	α-helix	trans	-61.3	-44.5	178.4	0	0	0	0	0	111.1	L264 V265 I271 I272	L264-A268 VanDerWaalsContact O-CB 3.3Å; L264-A268 WeakPolarHBondContact O-CB 3.46Å; L264-A268 PolarHBondContact O-N 2.92Å; V265-A268 PolarHBondContact O-N 2.84Å; A268-I271 PolarHBondContact O-N 3.04Å; A268-I272 HydrophobicContact CB-CD1 4.42Å; A268-I272 VanDerWaalsContact O-CB 3.26Å; A268-I272 WeakPolarHBondContact O-CB 3.42Å; A268-I272 WeakPolarHBondContact O-CD1 3.41Å; A268-I272 WeakPolarHBondContact O-CG1 3.12Å; A268-I272 PolarHBondContact O-N 3.13Å
269	V	81	Confident	77.4	Confident	28 Å²	28	46.3 Å²	46.3	17%	0.17	24%	0.244	C	C	.	.	H	α-helix	trans	-61.3	-47.2	176.8	171.5	0	0	0	0	110.8	V265 V266 V267 I271 I272 C273 L312 L316	V265-V269 HydrophobicContact CG1-CG2 4.27Å; V265-V269 WeakPolarHBondContact O-CB 3.42Å; V265-V269 VanDerWaalsContact O-CG2 3.24Å; V265-V269 WeakPolarHBondContact O-CG2 3.3Å; V265-V269 PolarHBondContact O-N 3.47Å; V266-V269 PolarHBondContact O-N 3.32Å; V267-V269 VanDerWaalsContact C-N 3.34Å; V267-V269 PolarHBondContact O-N 2.88Å; V269-I271 PolarHBondContact O-N 2.79Å; V269-I272 PolarHBondContact O-N 3.26Å; V269-C273 VanDerWaalsContact O-CB 3.27Å; V269-C273 WeakPolarHBondContact O-CB 3.48Å; V269-C273 PolarHBondContact O-N 3.34Å; V269-C273 PolarHBondContact O-SG 2.88Å; V269-C273 VanDerWaalsContact O-SG 3.34Å; V269-L312 HydrophobicContact CG1-CD1 3.98Å; V269-L316 HydrophobicContact CB-CD1 4.45Å; V269-L316 HydrophobicContact CG1-CD1 4.3Å; V269-L316 HydrophobicContact CG2-CD1 4.4Å
270	F	78.3	Confident	78.3	Confident	4 Å²	4	45.2 Å²	45.2	2%	0.018	24%	0.238	C	C	.	.	H	α-helix	trans	-58.6	-48.7	177.7	178.4	-98.7	0	0	0	112.2	T136 L139 F222 V226 V266 V267 C273 W274	T136-F270 HydrophobicContact CG2-CE2 4.42Å; T136-F270 HydrophobicContact CG2-CZ 3.79Å; T136-F270 WeakPolarHBondContact OG1-CE2 3.33Å; T136-F270 WeakPolarHBondContact OG1-CZ 3.5Å; L139-F270 HydrophobicContact CD1-CB 4.42Å; L139-F270 HydrophobicContact CD1-CD2 3.38Å; L139-F270 HydrophobicContact CD1-CE2 3.87Å; L139-F270 HydrophobicContact CD1-CG 4.06Å; F222-F270 HydrophobicContact CD2-CE1 4.23Å; F222-F270 HydrophobicContact CE2-CE1 4.4Å; V226-F270 HydrophobicContact CG2-CD1 4.32Å; V226-F270 HydrophobicContact CG2-CE1 3.88Å; V266-F270 PolarHBondContact O-N 2.85Å; V267-F270 PolarHBondContact O-N 2.85Å; F270-C273 PolarHBondContact O-N 3.17Å; F270-W274 AromaticContact CD2-CD1 3.43Å; F270-W274 VanDerWaalsContact CD2-CD1 3.43Å; F270-W274 HydrophobicContact CD2-CG 4.32Å; F270-W274 AromaticContact CD2-NE1 3.75Å; F270-W274 AromaticContact CE2-CD1 3.43Å; F270-W274 VanDerWaalsContact CE2-CD1 3.43Å; F270-W274 HydrophobicContact CE2-CD2 4.49Å; F270-W274 AromaticContact CE2-CG 3.99Å; F270-W274 HydrophobicContact CE2-CG 3.99Å; F270-W274 AromaticContact CE2-NE1 3.61Å; F270-W274 HydrophobicContact CZ-CG 4.32Å; F270-W274 WeakPolarHBondContact O-CB 3.31Å; F270-W274 PolarHBondContact O-N 3.39Å
271	I	83.2	Confident	79	Confident	56 Å²	56	46.5 Å²	46.5	29%	0.287	25%	0.245	S	C	.	.	H	α-helix	trans	-62.8	-49.2	178.8	-67.3	173	0	0	0	110.1	V226 V267 A268 V269 C273 W274 T275	V226-I271 HydrophobicContact CG1-CD1 4.28Å; V226-I271 HydrophobicContact CG2-CG1 4.36Å; V267-I271 HydrophobicContact CG1-CD1 3.75Å; V267-I271 HydrophobicContact CG1-CG1 4.38Å; V267-I271 WeakPolarHBondContact O-CG1 3.34Å; V267-I271 PolarHBondContact O-N 2.9Å; A268-I271 PolarHBondContact O-N 3.04Å; V269-I271 PolarHBondContact O-N 2.79Å; I271-C273 VanDerWaalsContact C-N 3.3Å; I271-C273 PolarHBondContact O-N 3.33Å; I271-W274 PolarHBondContact O-N 3.33Å; I271-T275 WeakPolarHBondContact CG2-OG1 3.39Å; I271-T275 WeakPolarHBondContact O-CB 3.26Å; I271-T275 PolarHBondContact O-N 3.1Å; I271-T275 PolarHBondContact O-OG1 3.28Å
272	I	87.4	Confident	79.6	Confident	110 Å²	110	40.1 Å²	40.1	56%	0.564	22%	0.223	S	C	*	.	H	α-helix	trans	-62	-40.3	-177.7	-69.9	165.2	0	0	0	111	A268 V269 P276 L305	A268-I272 HydrophobicContact CB-CD1 4.42Å; A268-I272 VanDerWaalsContact O-CB 3.26Å; A268-I272 WeakPolarHBondContact O-CB 3.42Å; A268-I272 WeakPolarHBondContact O-CD1 3.41Å; A268-I272 WeakPolarHBondContact O-CG1 3.12Å; A268-I272 PolarHBondContact O-N 3.13Å; V269-I272 PolarHBondContact O-N 3.26Å; I272-P276 WeakPolarHBondContact O-CD 3.19Å; I272-L305 WeakPolarHBondContact O-CD2 3.4Å
273	C	85.8	Confident	80.4	Confident	4 Å²	4	41.7 Å²	41.7	3%	0.027	24%	0.235	C	C	.	.	H	α-helix	trans	-74.1	-39.3	-178.1	-72	0	0	0	0	113.5	V269 F270 I271 L305 N309	V269-C273 VanDerWaalsContact O-CB 3.27Å; V269-C273 WeakPolarHBondContact O-CB 3.48Å; V269-C273 PolarHBondContact O-N 3.34Å; V269-C273 PolarHBondContact O-SG 2.88Å; V269-C273 VanDerWaalsContact O-SG 3.34Å; F270-C273 PolarHBondContact O-N 3.17Å; I271-C273 VanDerWaalsContact C-N 3.3Å; I271-C273 PolarHBondContact O-N 3.33Å; C273-L305 HydrophobicContact CB-CG 4.41Å; C273-L305 WeakPolarHBondContact CB-O 3.13Å; C273-N309 HydrophobicContact CB-CB 3.84Å
274	W	85.3	Confident	81.2	Confident	23 Å²	23	45 Å²	45	9%	0.087	25%	0.25	C	C	.	.	H	α-helix	trans	-94.2	-29.5	-173.4	-75.4	90.7	0	0	0	114.4	M132 F222 F270 I271 P276 I277 Q278 N309	M132-W274 HydrophobicContact CB-CH2 3.79Å; M132-W274 HydrophobicContact CB-CZ3 4.13Å; M132-W274 HydrophobicContact CG-CH2 3.76Å; M132-W274 HydrophobicContact CG-CZ3 3.63Å; M132-W274 HydrophobicContact SD-CZ3 4Å; F222-W274 HydrophobicContact CD2-CB 4.17Å; F222-W274 HydrophobicContact CE2-CB 4.17Å; F270-W274 AromaticContact CD2-CD1 3.43Å; F270-W274 VanDerWaalsContact CD2-CD1 3.43Å; F270-W274 HydrophobicContact CD2-CG 4.32Å; F270-W274 AromaticContact CD2-NE1 3.75Å; F270-W274 AromaticContact CE2-CD1 3.43Å; F270-W274 VanDerWaalsContact CE2-CD1 3.43Å; F270-W274 HydrophobicContact CE2-CD2 4.49Å; F270-W274 AromaticContact CE2-CG 3.99Å; F270-W274 HydrophobicContact CE2-CG 3.99Å; F270-W274 AromaticContact CE2-NE1 3.61Å; F270-W274 HydrophobicContact CZ-CG 4.32Å; F270-W274 WeakPolarHBondContact O-CB 3.31Å; F270-W274 PolarHBondContact O-N 3.39Å; I271-W274 PolarHBondContact O-N 3.33Å; W274-P276 VanDerWaalsContact C-CD 3.5Å; W274-I277 HydrophobicContact CE3-CG2 4.28Å; W274-I277 VanDerWaalsContact O-CG2 3.25Å; W274-I277 WeakPolarHBondContact O-CG2 3.35Å; W274-I277 PolarHBondContact O-N 3.1Å; W274-Q278 HydrophobicContact CB-CG 4.49Å; W274-Q278 HydrophobicContact CE3-CG 4.48Å; W274-Q278 WeakPolarHBondContact O-CB 3.35Å; W274-Q278 WeakPolarHBondContact O-CG 3.13Å; W274-Q278 PolarHBondContact O-N 3.23Å; W274-N309 PolarHBondContact NE1-ND2 3.43Å; W274-N309 VanDerWaalsContact NE1-ND2 3.11Å
275	T	87.4	Confident	81.6	Confident	34 Å²	34	41.1 Å²	41.1	21%	0.209	23%	0.231	C	C	.	.	H	α-helix	trans	-55.8	-46.6	-176.5	-57.4	0	0	0	0	113	F222 I271 I277 Q278 I279	F222-T275 HydrophobicContact CZ-CG2 4.38Å; F222-T275 WeakPolarHBondContact CZ-OG1 3.34Å; I271-T275 WeakPolarHBondContact CG2-OG1 3.39Å; I271-T275 WeakPolarHBondContact O-CB 3.26Å; I271-T275 PolarHBondContact O-N 3.1Å; I271-T275 PolarHBondContact O-OG1 3.28Å; T275-I277 PolarHBondContact O-N 3.07Å; T275-Q278 PolarHBondContact O-N 3.38Å; T275-I279 HydrophobicContact CG2-CD1 3.45Å; T275-I279 VanDerWaalsContact CG2-CD1 3.45Å; T275-I279 HydrophobicContact CG2-CG1 4.05Å; T275-I279 WeakPolarHBondContact O-CG1 3.35Å; T275-I279 PolarHBondContact O-N 2.99Å
276	P	87.4	Confident	81.9	Confident	43 Å²	43	43.6 Å²	43.6	28%	0.279	24%	0.241	S	C	.	.	H	α-helix	trans	-60.7	-47.1	-174.9	-25.4	37.3	0	0	0	112.3	I272 W274 F280 C302 L305	I272-P276 WeakPolarHBondContact O-CD 3.19Å; W274-P276 VanDerWaalsContact C-CD 3.5Å; P276-F280 WeakPolarHBondContact O-CB 3.34Å; P276-F280 PolarHBondContact O-N 2.96Å; P276-C302 HydrophobicContact CB-CB 4Å; P276-C302 WeakPolarHBondContact CB-SG 3.38Å; P276-L305 HydrophobicContact CG-CD2 4.07Å
277	I	83.6	Confident	82.1	Confident	23 Å²	23	45.2 Å²	45.2	12%	0.118	26%	0.264	C	S	.	.	H	α-helix	trans	-69.6	-38.6	-179.8	-171.5	57.6	0	0	0	112	W274 T275 I279 F280 V281 C302 T303	W274-I277 HydrophobicContact CE3-CG2 4.28Å; W274-I277 VanDerWaalsContact O-CG2 3.25Å; W274-I277 WeakPolarHBondContact O-CG2 3.35Å; W274-I277 PolarHBondContact O-N 3.1Å; T275-I277 PolarHBondContact O-N 3.07Å; I277-I279 PolarHBondContact O-N 3.4Å; I277-F280 PolarHBondContact O-N 3.39Å; I277-V281 HydrophobicContact CD1-CG2 4.03Å; I277-V281 HydrophobicContact CG1-CG2 4.27Å; I277-V281 WeakPolarHBondContact O-CG2 3.49Å; I277-V281 PolarHBondContact O-N 2.9Å; I277-C302 HydrophobicContact CB-CB 4.08Å; I277-C302 HydrophobicContact CD1-CB 4.23Å; I277-T303 VanDerWaalsContact CD1-OG1 3.25Å; I277-T303 WeakPolarHBondContact CD1-OG1 3.33Å
278	Q	86.3	Confident	82.3	Confident	9 Å²	9	46.5 Å²	46.5	4%	0.042	28%	0.277	C	S	.	.	H	α-helix	trans	-65.8	-39.1	179.5	-70.4	-70	-5	0	0	112.2	F218 S221 F222 W274 T275 L282	F218-Q278 HydrophobicContact CD2-CB 4.02Å; F218-Q278 HydrophobicContact CE2-CB 4.2Å; S221-Q278 PolarHBondContact OG-NE2 3.11Å; F222-Q278 HydrophobicContact CB-CG 4.01Å; F222-Q278 HydrophobicContact CD1-CB 4.38Å; F222-Q278 HydrophobicContact CD2-CG 4.18Å; F222-Q278 HydrophobicContact CG-CB 4.31Å; F222-Q278 HydrophobicContact CG-CG 4.02Å; W274-Q278 HydrophobicContact CB-CG 4.49Å; W274-Q278 HydrophobicContact CE3-CG 4.48Å; W274-Q278 WeakPolarHBondContact O-CB 3.35Å; W274-Q278 WeakPolarHBondContact O-CG 3.13Å; W274-Q278 PolarHBondContact O-N 3.23Å; T275-Q278 PolarHBondContact O-N 3.38Å; Q278-L282 VanDerWaalsContact O-CB 3.29Å; Q278-L282 WeakPolarHBondContact O-CB 3.36Å; Q278-L282 PolarHBondContact O-N 2.9Å; Q278-L282 VanDerWaalsContact O-N 3.14Å
279	I	86.3	Confident	81.7	Confident	88 Å²	88	52.2 Å²	52.2	45%	0.451	29%	0.293	S	S	.	.	H	α-helix	trans	-68.1	-44.5	173.8	-66.9	176.3	0	0	0	110.2	T275 I277 V281 L282 V283	T275-I279 HydrophobicContact CG2-CD1 3.45Å; T275-I279 VanDerWaalsContact CG2-CD1 3.45Å; T275-I279 HydrophobicContact CG2-CG1 4.05Å; T275-I279 WeakPolarHBondContact O-CG1 3.35Å; T275-I279 PolarHBondContact O-N 2.99Å; I277-I279 PolarHBondContact O-N 3.4Å; I279-V281 PolarHBondContact O-N 3.32Å; I279-L282 PolarHBondContact O-N 3.24Å; I279-V283 HydrophobicContact CG2-CG2 4.22Å; I279-V283 WeakPolarHBondContact O-CB 3.37Å; I279-V283 VanDerWaalsContact O-CG2 3.3Å; I279-V283 WeakPolarHBondContact O-CG2 3.19Å; I279-V283 PolarHBondContact O-N 3.09Å
280	F	83.3	Confident	80.9	Confident	36 Å²	36	52.3 Å²	52.3	16%	0.158	30%	0.297	C	S	.	.	H	α-helix	trans	-61.4	-46.9	-178.1	-166.6	-91.9	0	0	0	112.2	P276 I277 V283 Q284 A290 E295 S299	P276-F280 WeakPolarHBondContact O-CB 3.34Å; P276-F280 PolarHBondContact O-N 2.96Å; I277-F280 PolarHBondContact O-N 3.39Å; F280-V283 PolarHBondContact O-N 3.42Å; F280-Q284 HydrophobicContact CD1-CG 4.44Å; F280-Q284 HydrophobicContact CE1-CG 4.14Å; F280-Q284 PolarHBondContact O-N 2.9Å; F280-Q284 VanDerWaalsContact O-N 3.08Å; F280-A290 HydrophobicContact CZ-CB 4.22Å; F280-E295 WeakPolarHBondContact CZ-O 3.49Å; F280-S299 VanDerWaalsContact CD1-OG 3.32Å; F280-S299 WeakPolarHBondContact CD1-OG 3.48Å; F280-S299 WeakPolarHBondContact CE1-OG 3.22Å
281	V	80.1	Confident	80.3	Confident	53 Å²	53	58.9 Å²	58.9	32%	0.321	33%	0.328	S	S	.	.	H	α-helix	trans	-62.5	-44	176.1	172.1	0	0	0	0	110.9	I277 I279 V283 Q284 C285	I277-V281 HydrophobicContact CD1-CG2 4.03Å; I277-V281 HydrophobicContact CG1-CG2 4.27Å; I277-V281 WeakPolarHBondContact O-CG2 3.49Å; I277-V281 PolarHBondContact O-N 2.9Å; I279-V281 PolarHBondContact O-N 3.32Å; V281-V283 VanDerWaalsContact C-N 3.35Å; V281-V283 PolarHBondContact O-N 2.92Å; V281-Q284 PolarHBondContact O-N 3.12Å; V281-C285 PolarHBondContact O-N 3.31Å; V281-C285 PolarHBondContact O-SG 3.42Å; V281-C285 VanDerWaalsContact O-SG 3.33Å
282	L	82.6	Confident	80	Confident	33 Å²	33	58.8 Å²	58.8	17%	0.173	33%	0.332	C	S	.	.	H	α-helix	trans	-60.8	-44	178.3	179.9	64	0	0	0	112	I215 F218 Q278 I279 Q284 C285 L286	I215-L282 HydrophobicContact CG1-CD1 3.87Å; F218-L282 HydrophobicContact CB-CD1 4.49Å; F218-L282 HydrophobicContact CD1-CD2 4.05Å; F218-L282 HydrophobicContact CD2-CB 4.48Å; F218-L282 HydrophobicContact CD2-CD2 4.14Å; F218-L282 HydrophobicContact CE1-CD2 4.06Å; F218-L282 HydrophobicContact CE2-CD2 4.18Å; F218-L282 HydrophobicContact CG-CD2 4.09Å; F218-L282 HydrophobicContact CZ-CD2 4.13Å; Q278-L282 VanDerWaalsContact O-CB 3.29Å; Q278-L282 WeakPolarHBondContact O-CB 3.36Å; Q278-L282 PolarHBondContact O-N 2.9Å; Q278-L282 VanDerWaalsContact O-N 3.14Å; I279-L282 PolarHBondContact O-N 3.24Å; L282-Q284 VanDerWaalsContact C-N 3.33Å; L282-Q284 PolarHBondContact O-N 2.82Å; L282-C285 PolarHBondContact O-N 3.02Å; L282-L286 HydrophobicContact CD1-CD1 4.24Å; L282-L286 HydrophobicContact CD1-CG 4.4Å; L282-L286 HydrophobicContact CG-CD1 4.1Å; L282-L286 VanDerWaalsContact O-CG 3.24Å; L282-L286 WeakPolarHBondContact O-CG 2.94Å; L282-L286 PolarHBondContact O-N 3.29Å; L282-L286 VanDerWaalsContact O-N 3.1Å
283	V	84	Confident	79.3	Confident	71 Å²	71	58.9 Å²	58.9	43%	0.43	33%	0.33	S	S	.	.	H	α-helix	trans	-62.6	-41.4	178.8	167.2	0	0	0	0	110.9	I279 F280 V281 L286 A288	I279-V283 HydrophobicContact CG2-CG2 4.22Å; I279-V283 WeakPolarHBondContact O-CB 3.37Å; I279-V283 VanDerWaalsContact O-CG2 3.3Å; I279-V283 WeakPolarHBondContact O-CG2 3.19Å; I279-V283 PolarHBondContact O-N 3.09Å; F280-V283 PolarHBondContact O-N 3.42Å; V281-V283 VanDerWaalsContact C-N 3.35Å; V281-V283 PolarHBondContact O-N 2.92Å; V283-L286 PolarHBondContact O-N 3.21Å; V283-A288 HydrophobicContact CG1-CB 3.52Å; V283-A288 WeakPolarHBondContact O-CB 3.01Å; V283-A288 PolarHBondContact O-N 3.35Å
284	Q	79.2	Confident	78.8	Confident	78 Å²	78	64.1 Å²	64.1	36%	0.364	36%	0.357	S	S	.	.	H	α-helix	trans	-63.7	-47.7	175.3	-76.3	-173.3	92.1	0	0	112.7	F280 V281 L282 L286 G287 A288	F280-Q284 HydrophobicContact CD1-CG 4.44Å; F280-Q284 HydrophobicContact CE1-CG 4.14Å; F280-Q284 PolarHBondContact O-N 2.9Å; F280-Q284 VanDerWaalsContact O-N 3.08Å; V281-Q284 PolarHBondContact O-N 3.12Å; L282-Q284 VanDerWaalsContact C-N 3.33Å; L282-Q284 PolarHBondContact O-N 2.82Å; Q284-L286 PolarHBondContact O-N 3.4Å; Q284-L286 VanDerWaalsContact O-N 3.15Å; Q284-G287 PolarHBondContact O-N 3.47Å; Q284-A288 WeakPolarHBondContact CA-O 3.22Å
285	C	78.3	Confident	78.3	Confident	15 Å²	15	66.8 Å²	66.8	10%	0.101	37%	0.37	C	S	.	.	H	α-helix	trans	-63.7	-20.8	178.7	-66.5	0	0	0	0	113.1	D210 P211 V281 L282 G287	D210-C285 WeakPolarHBondContact OD2-CA 3.27Å; P211-C285 WeakPolarHBondContact CA-O 2.71Å; P211-C285 VanDerWaalsContact CB-O 3.29Å; P211-C285 WeakPolarHBondContact CB-O 3.43Å; V281-C285 PolarHBondContact O-N 3.31Å; V281-C285 PolarHBondContact O-SG 3.42Å; V281-C285 VanDerWaalsContact O-SG 3.33Å; L282-C285 PolarHBondContact O-N 3.02Å; C285-G287 VanDerWaalsContact C-N 3.26Å
286	L	81.2	Confident	77.7	Confident	111 Å²	111	67.7 Å²	67.7	58%	0.581	37%	0.374	S	S	*	.	T	Hydrogen-bonded Turn	trans	-84.5	4.2	174.1	-68.5	173.4	0	0	0	113.4	P211 I215 L282 V283 Q284	P211-L286 HydrophobicContact CB-CD2 4.47Å; I215-L286 HydrophobicContact CD1-CD2 4.36Å; L282-L286 HydrophobicContact CD1-CD1 4.24Å; L282-L286 HydrophobicContact CD1-CG 4.4Å; L282-L286 HydrophobicContact CG-CD1 4.1Å; L282-L286 VanDerWaalsContact O-CG 3.24Å; L282-L286 WeakPolarHBondContact O-CG 2.94Å; L282-L286 PolarHBondContact O-N 3.29Å; L282-L286 VanDerWaalsContact O-N 3.1Å; V283-L286 PolarHBondContact O-N 3.21Å; Q284-L286 PolarHBondContact O-N 3.4Å; Q284-L286 VanDerWaalsContact O-N 3.15Å
287	G	73.3	Confident	77.2	Confident	63 Å²	63	66.6 Å²	66.6	65%	0.649	37%	0.369	S	S	*	.	T	Hydrogen-bonded Turn	trans	102.5	7.2	172.3	0	0	0	0	0	115.3	Q284 C285	Q284-G287 PolarHBondContact O-N 3.47Å; C285-G287 VanDerWaalsContact C-N 3.26Å
288	A	74.8	Confident	77	Confident	49 Å²	49	69.3 Å²	69.3	41%	0.405	38%	0.382	S	S	.	.			trans	-79.4	123.8	171	0	0	0	0	0	110.1	V283 Q284	V283-A288 HydrophobicContact CG1-CB 3.52Å; V283-A288 WeakPolarHBondContact O-CB 3.01Å; V283-A288 PolarHBondContact O-N 3.35Å; Q284-A288 WeakPolarHBondContact CA-O 3.22Å
289	K	67.2	Low	76.6	Confident	165 Å²	165	69.8 Å²	69.8	72%	0.717	39%	0.387	S	S	*	.			trans	-91.7	133.4	175.8	-65.5	-176.4	-179.9	-178.4	0	109.8	E291	K289-E291 HydrophobicContact CB-CG 3.85Å; K289-E291 PolarHBondContact O-N 2.9Å
290	A	63.5	Low	76.2	Confident	30 Å²	30	66.4 Å²	66.4	25%	0.248	37%	0.371	C	S	.	.			trans	-79.5	99.9	167	0	0	0	0	0	108.1	F280 E295	F280-A290 HydrophobicContact CZ-CB 4.22Å; A290-E295 WeakPolarHBondContact CA-OE2 3.49Å; A290-E295 HydrophobicContact CB-CB 3.86Å
291	E	66.6	Low	76.1	Confident	143 Å²	143	71.3 Å²	71.3	67%	0.668	39%	0.392	S	S	*	.			trans	-105.4	-11	-177.3	-64.2	-173.8	174.6	0	0	111.9	F43 K289 E295	F43-E291 VanDerWaalsContact CZ-O 3.26Å; F43-E291 WeakPolarHBondContact CZ-O 3.32Å; K289-E291 HydrophobicContact CB-CG 3.85Å; K289-E291 PolarHBondContact O-N 2.9Å; E291-E295 PolarHBondContact N-OE2 3.22Å
292	S	76.3	Confident	76.4	Confident	53 Å²	53	69.3 Å²	69.3	37%	0.371	38%	0.38	S	S	.	.	S	Bend	trans	-97.3	142.2	177.9	-177	0	0	0	0	112.6	L294 E295 L296	S292-L294 PolarHBondContact O-N 2.83Å; S292-L294 VanDerWaalsContact O-N 3.15Å; S292-L294 PolarHBondContact OG-N 3.04Å; S292-E295 PolarHBondContact N-OE2 3.46Å; S292-E295 VanDerWaalsContact N-OE2 3.09Å; S292-E295 WeakPolarHBondContact O-CB 3.5Å; S292-E295 PolarHBondContact O-N 2.96Å; S292-L296 PolarHBondContact O-N 3.48Å; S292-L296 VanDerWaalsContact O-N 3.17Å
293	E	73	Confident	76.4	Confident	112 Å²	112	69.4 Å²	69.4	52%	0.523	38%	0.382	S	S	.	.	H	α-helix	trans	-51.4	-35.1	167.8	-62.4	-177.1	179.2	0	0	112.2	A297	E293-A297 WeakPolarHBondContact O-CB 3.45Å; E293-A297 PolarHBondContact O-N 3.11Å
294	L	75.6	Confident	76.5	Confident	115 Å²	115	66.4 Å²	66.4	60%	0.602	37%	0.365	S	S	*	.	H	α-helix	trans	-66.7	-40	178.1	-179.4	63.6	0	0	0	111.6	S292 A297 I298	S292-L294 PolarHBondContact O-N 2.83Å; S292-L294 VanDerWaalsContact O-N 3.15Å; S292-L294 PolarHBondContact OG-N 3.04Å; L294-A297 PolarHBondContact O-N 3.39Å; L294-I298 HydrophobicContact CD1-CD1 4.16Å; L294-I298 HydrophobicContact CD1-CG1 4.45Å; L294-I298 HydrophobicContact CG-CD1 3.91Å; L294-I298 WeakPolarHBondContact O-CB 3.43Å; L294-I298 WeakPolarHBondContact O-CD1 3.46Å; L294-I298 WeakPolarHBondContact O-CG1 3.25Å; L294-I298 PolarHBondContact O-N 2.77Å
295	E	74.7	Confident	76.8	Confident	78 Å²	78	64.9 Å²	64.9	36%	0.364	36%	0.359	S	S	.	.	H	α-helix	trans	-68.6	-40.1	-179.8	-68.8	169.8	157.3	0	0	111.1	F280 A290 E291 S292 I298 S299	F280-E295 WeakPolarHBondContact CZ-O 3.49Å; A290-E295 WeakPolarHBondContact CA-OE2 3.49Å; A290-E295 HydrophobicContact CB-CB 3.86Å; E291-E295 PolarHBondContact N-OE2 3.22Å; S292-E295 PolarHBondContact N-OE2 3.46Å; S292-E295 VanDerWaalsContact N-OE2 3.09Å; S292-E295 WeakPolarHBondContact O-CB 3.5Å; S292-E295 PolarHBondContact O-N 2.96Å; E295-I298 PolarHBondContact O-N 3.04Å; E295-S299 PolarHBondContact O-N 2.9Å
296	L	74	Confident	77.2	Confident	53 Å²	53	64.5 Å²	64.5	28%	0.277	36%	0.358	S	S	.	.	H	α-helix	trans	-66.8	-42.2	175.4	-170.3	61.3	0	0	0	111.6	F43 L44 S292 I298 S299 C300	F43-L296 HydrophobicContact CB-CD2 4.2Å; F43-L296 HydrophobicContact CD1-CD2 3.64Å; F43-L296 HydrophobicContact CG-CD2 4.37Å; L44-L296 HydrophobicContact CD1-CD2 3.49Å; L44-L296 VanDerWaalsContact CD1-CD2 3.49Å; L44-L296 HydrophobicContact CD1-CG 3.86Å; L44-L296 HydrophobicContact CD2-CD2 4.39Å; L44-L296 HydrophobicContact CD2-CG 4.37Å; L44-L296 HydrophobicContact CG-CD2 3.63Å; L44-L296 HydrophobicContact CG-CG 4.1Å; S292-L296 PolarHBondContact O-N 3.48Å; S292-L296 VanDerWaalsContact O-N 3.17Å; L296-I298 PolarHBondContact O-N 3.09Å; L296-S299 VanDerWaalsContact O-CB 3.32Å; L296-S299 WeakPolarHBondContact O-CB 3.49Å; L296-S299 PolarHBondContact O-N 2.03Å; L296-C300 PolarHBondContact O-N 3.14Å; L296-C300 PolarHBondContact O-SG 2.99Å; L296-C300 VanDerWaalsContact O-SG 3.33Å
297	A	77.2	Confident	77.5	Confident	21 Å²	21	60.7 Å²	60.7	17%	0.174	34%	0.336	C	S	.	.	H	α-helix	trans	-62.4	-41.2	174.9	0	0	0	0	0	112.5	L44 I48 E293 L294 S299 C300 F301	L44-A297 HydrophobicContact CD2-CB 4.43Å; I48-A297 HydrophobicContact CD1-CB 3.94Å; I48-A297 HydrophobicContact CG2-CB 4.2Å; E293-A297 WeakPolarHBondContact O-CB 3.45Å; E293-A297 PolarHBondContact O-N 3.11Å; L294-A297 PolarHBondContact O-N 3.39Å; A297-S299 VanDerWaalsContact C-N 3.35Å; A297-C300 PolarHBondContact O-N 3.49Å; A297-F301 WeakPolarHBondContact O-CB 3.37Å; A297-F301 PolarHBondContact O-N 3.21Å
298	I	80.3	Confident	78.1	Confident	79 Å²	79	58.5 Å²	58.5	41%	0.405	31%	0.312	S	S	.	.	H	α-helix	trans	-62	-44.3	173.9	-72.1	166.3	0	0	0	110.2	L294 E295 L296 C300 F301 C302	L294-I298 HydrophobicContact CD1-CD1 4.16Å; L294-I298 HydrophobicContact CD1-CG1 4.45Å; L294-I298 HydrophobicContact CG-CD1 3.91Å; L294-I298 WeakPolarHBondContact O-CB 3.43Å; L294-I298 WeakPolarHBondContact O-CD1 3.46Å; L294-I298 WeakPolarHBondContact O-CG1 3.25Å; L294-I298 PolarHBondContact O-N 2.77Å; E295-I298 PolarHBondContact O-N 3.04Å; L296-I298 PolarHBondContact O-N 3.09Å; I298-C300 PolarHBondContact O-N 3.18Å; I298-F301 PolarHBondContact O-N 3.48Å; I298-C302 WeakPolarHBondContact O-CB 3.04Å; I298-C302 PolarHBondContact O-N 2.86Å; I298-C302 PolarHBondContact O-SG 3.22Å
299	S	77.8	Confident	78.7	Confident	19 Å²	19	56.3 Å²	56.3	13%	0.133	29%	0.293	C	S	.	.	H	α-helix	trans	-56.2	-51.7	176.9	-166.6	0	0	0	0	112.1	F280 E295 L296 A297 F301 C302 T303	F280-S299 VanDerWaalsContact CD1-OG 3.32Å; F280-S299 WeakPolarHBondContact CD1-OG 3.48Å; F280-S299 WeakPolarHBondContact CE1-OG 3.22Å; E295-S299 PolarHBondContact O-N 2.9Å; L296-S299 VanDerWaalsContact O-CB 3.32Å; L296-S299 WeakPolarHBondContact O-CB 3.49Å; L296-S299 PolarHBondContact O-N 2.03Å; A297-S299 VanDerWaalsContact C-N 3.35Å; S299-F301 VanDerWaalsContact C-N 3.28Å; S299-F301 PolarHBondContact O-N 2.7Å; S299-C302 WeakPolarHBondContact O-CB 3.39Å; S299-C302 PolarHBondContact O-N 3.48Å; S299-C302 VanDerWaalsContact O-N 3.16Å; S299-T303 PolarHBondContact O-N 3.27Å; S299-T303 PolarHBondContact O-OG1 3.47Å; S299-T303 VanDerWaalsContact O-OG1 3.09Å
300	C	78.4	Confident	79.6	Confident	18 Å²	18	48.4 Å²	48.4	12%	0.122	26%	0.259	C	S	.	.	H	α-helix	trans	-60.3	-39.5	178.5	-64.1	0	0	0	0	112	I52 L296 A297 I298 T303 A304	I52-C300 HydrophobicContact CD1-CB 3.4Å; I52-C300 VanDerWaalsContact CD1-CB 3.4Å; I52-C300 HydrophobicContact CG1-CB 4.04Å; L296-C300 PolarHBondContact O-N 3.14Å; L296-C300 PolarHBondContact O-SG 2.99Å; L296-C300 VanDerWaalsContact O-SG 3.33Å; A297-C300 PolarHBondContact O-N 3.49Å; I298-C300 PolarHBondContact O-N 3.18Å; C300-T303 PolarHBondContact O-N 3.44Å; C300-A304 WeakPolarHBondContact O-CB 3.32Å; C300-A304 PolarHBondContact O-N 3.13Å
301	F	80.9	Confident	80.7	Confident	138 Å²	138	47.6 Å²	47.6	61%	0.605	25%	0.251	S	S	*	.	H	α-helix	trans	-65.8	-42.7	175.8	-179	-96.7	0	0	0	112.2	A297 I298 S299 T303 A304 L305	A297-F301 WeakPolarHBondContact O-CB 3.37Å; A297-F301 PolarHBondContact O-N 3.21Å; I298-F301 PolarHBondContact O-N 3.48Å; S299-F301 VanDerWaalsContact C-N 3.28Å; S299-F301 PolarHBondContact O-N 2.7Å; F301-T303 VanDerWaalsContact C-N 3.32Å; F301-T303 PolarHBondContact O-N 3.42Å; F301-A304 WeakPolarHBondContact O-CB 3.4Å; F301-A304 PolarHBondContact O-N 3.46Å; F301-L305 WeakPolarHBondContact O-CB 3.22Å; F301-L305 PolarHBondContact O-N 2.91Å
302	C	84.9	Confident	81.5	Confident	11 Å²	11	44 Å²	44	7%	0.074	24%	0.236	C	C	.	.	H	α-helix	trans	-61.1	-41.9	174.9	-68.5	0	0	0	0	111.6	P276 I277 I298 S299 L305 G306	P276-C302 HydrophobicContact CB-CB 4Å; P276-C302 WeakPolarHBondContact CB-SG 3.38Å; I277-C302 HydrophobicContact CB-CB 4.08Å; I277-C302 HydrophobicContact CD1-CB 4.23Å; I298-C302 WeakPolarHBondContact O-CB 3.04Å; I298-C302 PolarHBondContact O-N 2.86Å; I298-C302 PolarHBondContact O-SG 3.22Å; S299-C302 WeakPolarHBondContact O-CB 3.39Å; S299-C302 PolarHBondContact O-N 3.48Å; S299-C302 VanDerWaalsContact O-N 3.16Å; C302-L305 PolarHBondContact O-N 3.04Å; C302-G306 PolarHBondContact O-N 3.39Å
303	T	83.2	Confident	81.8	Confident	35 Å²	35	41.6 Å²	41.6	22%	0.215	22%	0.219	C	C	.	.	H	α-helix	trans	-62.3	-45.7	174.1	-60.5	0	0	0	0	111.5	I277 S299 C300 F301 L305 G306 Y307	I277-T303 VanDerWaalsContact CD1-OG1 3.25Å; I277-T303 WeakPolarHBondContact CD1-OG1 3.33Å; S299-T303 PolarHBondContact O-N 3.27Å; S299-T303 PolarHBondContact O-OG1 3.47Å; S299-T303 VanDerWaalsContact O-OG1 3.09Å; C300-T303 PolarHBondContact O-N 3.44Å; F301-T303 VanDerWaalsContact C-N 3.32Å; F301-T303 PolarHBondContact O-N 3.42Å; T303-L305 VanDerWaalsContact C-N 3.27Å; T303-L305 PolarHBondContact O-N 3.4Å; T303-G306 WeakPolarHBondContact O-CA 3.4Å; T303-G306 PolarHBondContact O-N 3.4Å; T303-G306 VanDerWaalsContact O-N 3.1Å; T303-Y307 HydrophobicContact CG2-CD2 3.98Å; T303-Y307 HydrophobicContact CG2-CE2 3.46Å; T303-Y307 VanDerWaalsContact CG2-CE2 3.46Å; T303-Y307 WeakPolarHBondContact O-CD2 2.99Å; T303-Y307 PolarHBondContact O-N 2.88Å
304	A	85.5	Confident	82	Confident	8 Å²	8	36.8 Å²	36.8	7%	0.066	20%	0.197	C	C	.	.	H	α-helix	trans	-58.2	-40.3	175.4	0	0	0	0	0	112.4	V55 Y56 C300 F301 G306 Y307 A308	V55-A304 HydrophobicContact CG1-CB 4.04Å; Y56-A304 HydrophobicContact CD1-CB 4.26Å; Y56-A304 HydrophobicContact CE1-CB 3.69Å; C300-A304 WeakPolarHBondContact O-CB 3.32Å; C300-A304 PolarHBondContact O-N 3.13Å; F301-A304 WeakPolarHBondContact O-CB 3.4Å; F301-A304 PolarHBondContact O-N 3.46Å; A304-G306 VanDerWaalsContact C-N 3.34Å; A304-Y307 PolarHBondContact O-N 3.07Å; A304-A308 WeakPolarHBondContact O-CB 3.48Å; A304-A308 PolarHBondContact O-N 3.46Å
305	L	86.4	Confident	81.9	Confident	47 Å²	47	34 Å²	34	25%	0.246	19%	0.185	C	C	.	.	H	α-helix	trans	-67.2	-35.9	177.2	-170.2	69.1	0	0	0	112.1	I272 C273 P276 F301 C302 T303 A308 N309	I272-L305 WeakPolarHBondContact O-CD2 3.4Å; C273-L305 HydrophobicContact CB-CG 4.41Å; C273-L305 WeakPolarHBondContact CB-O 3.13Å; P276-L305 HydrophobicContact CG-CD2 4.07Å; F301-L305 WeakPolarHBondContact O-CB 3.22Å; F301-L305 PolarHBondContact O-N 2.91Å; C302-L305 PolarHBondContact O-N 3.04Å; T303-L305 VanDerWaalsContact C-N 3.27Å; T303-L305 PolarHBondContact O-N 3.4Å; L305-A308 WeakPolarHBondContact O-CB 3.28Å; L305-A308 PolarHBondContact O-N 2.94Å; L305-N309 PolarHBondContact O-N 3Å
306	G	85.9	Confident	81.8	Confident	6 Å²	6	31.4 Å²	31.4	6%	0.062	17%	0.173	C	C	.	.	H	α-helix	trans	-58.3	-50.2	170.1	0	0	0	0	0	111.7	C302 T303 A304 A308 N309	C302-G306 PolarHBondContact O-N 3.39Å; T303-G306 WeakPolarHBondContact O-CA 3.4Å; T303-G306 PolarHBondContact O-N 3.4Å; T303-G306 VanDerWaalsContact O-N 3.1Å; A304-G306 VanDerWaalsContact C-N 3.34Å; G306-A308 VanDerWaalsContact C-N 3.31Å; G306-A308 PolarHBondContact O-N 2.84Å; G306-N309 WeakPolarHBondContact O-CB 3.3Å; G306-N309 PolarHBondContact O-N 3.43Å; G306-N309 VanDerWaalsContact O-N 3.13Å
307	Y	87.6	Confident	81.6	Confident	32 Å²	32	29.4 Å²	29.4	13%	0.125	16%	0.162	C	C	.	.	H	α-helix	trans	-65.4	-31.8	176.3	-66.3	-52.3	0	0	0	113.5	Y56 V59 L102 D128 T303 A304 N309 S310	Y56-Y307 HydrophobicContact CE1-CD2 4.1Å; V59-Y307 WeakPolarHBondContact CG1-O 3.44Å; L102-Y307 HydrophobicContact CD2-CD1 3.87Å; L102-Y307 HydrophobicContact CD2-CD2 3.47Å; L102-Y307 VanDerWaalsContact CD2-CD2 3.47Å; L102-Y307 HydrophobicContact CD2-CE1 4.04Å; L102-Y307 HydrophobicContact CD2-CE2 3.62Å; L102-Y307 HydrophobicContact CD2-CG 3.6Å; D128-Y307 PolarHBondContact OD2-OH 3.44Å; T303-Y307 HydrophobicContact CG2-CD2 3.98Å; T303-Y307 HydrophobicContact CG2-CE2 3.46Å; T303-Y307 VanDerWaalsContact CG2-CE2 3.46Å; T303-Y307 WeakPolarHBondContact O-CD2 2.99Å; T303-Y307 PolarHBondContact O-N 2.88Å; A304-Y307 PolarHBondContact O-N 3.07Å; Y307-N309 PolarHBondContact O-N 3.48Å; Y307-S310 WeakPolarHBondContact O-CB 3.42Å; Y307-S310 PolarHBondContact O-N 3.21Å; Y307-S310 VanDerWaalsContact O-N 3.07Å
308	A	86.7	Confident	81.1	Confident	17 Å²	17	29.8 Å²	29.8	14%	0.14	17%	0.165	C	C	.	.	H	α-helix	trans	-60.9	-26.9	174.8	0	0	0	0	0	112.3	V59 A304 L305 G306 S310 S311 L312	V59-A308 HydrophobicContact CG2-CB 4.31Å; A304-A308 WeakPolarHBondContact O-CB 3.48Å; A304-A308 PolarHBondContact O-N 3.46Å; L305-A308 WeakPolarHBondContact O-CB 3.28Å; L305-A308 PolarHBondContact O-N 2.94Å; G306-A308 VanDerWaalsContact C-N 3.31Å; G306-A308 PolarHBondContact O-N 2.84Å; A308-S310 PolarHBondContact O-N 3.47Å; A308-S311 PolarHBondContact O-N 3.27Å; A308-S311 VanDerWaalsContact O-N 3.1Å; A308-S311 PolarHBondContact O-OG 3.38Å; A308-L312 WeakPolarHBondContact O-CB 3.4Å; A308-L312 VanDerWaalsContact O-CG 3.22Å; A308-L312 WeakPolarHBondContact O-CG 3.49Å; A308-L312 PolarHBondContact O-N 2.9Å
309	N	86.7	Confident	80.3	Confident	2 Å²	2	32.7 Å²	32.7	1%	0.011	18%	0.176	C	C	.	.	H	α-helix	trans	-55.1	-41.5	173	-176.3	67.7	0	0	0	111.9	C273 W274 L305 G306 Y307 S311 L312 N313	C273-N309 HydrophobicContact CB-CB 3.84Å; W274-N309 PolarHBondContact NE1-ND2 3.43Å; W274-N309 VanDerWaalsContact NE1-ND2 3.11Å; L305-N309 PolarHBondContact O-N 3Å; G306-N309 WeakPolarHBondContact O-CB 3.3Å; G306-N309 PolarHBondContact O-N 3.43Å; G306-N309 VanDerWaalsContact O-N 3.13Å; Y307-N309 PolarHBondContact O-N 3.48Å; N309-S311 VanDerWaalsContact C-N 3.32Å; N309-S311 PolarHBondContact O-N 3.16Å; N309-L312 PolarHBondContact O-N 3.48Å; N309-N313 PolarHBondContact O-N 3.33Å; N309-N313 PolarHBondContact O-ND2 2.94Å
310	S	87.4	Confident	79.4	Confident	0 Å²	0	33.4 Å²	33.4	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-67.9	-28.3	179.1	-66.4	0	0	0	0	113.4	N67 D95 Y307 A308	N67-S310 PolarHBondContact ND2-O 2.9Å; D95-S310 VanDerWaalsContact CG-CB 3.47Å; D95-S310 WeakPolarHBondContact OD1-CB 3.48Å; D95-S310 PolarHBondContact OD1-OG 3.06Å; Y307-S310 WeakPolarHBondContact O-CB 3.42Å; Y307-S310 PolarHBondContact O-N 3.21Å; Y307-S310 VanDerWaalsContact O-N 3.07Å; A308-S310 PolarHBondContact O-N 3.47Å
311	S	86.1	Confident	78.8	Confident	12 Å²	12	34.1 Å²	34.1	8%	0.084	18%	0.18	C	C	.	.	H	α-helix	trans	-87.7	-23.9	176.7	68.3	0	0	0	0	113.4	A308 N309	A308-S311 PolarHBondContact O-N 3.27Å; A308-S311 VanDerWaalsContact O-N 3.1Å; A308-S311 PolarHBondContact O-OG 3.38Å; N309-S311 VanDerWaalsContact C-N 3.32Å; N309-S311 PolarHBondContact O-N 3.16Å
312	L	84	Confident	78	Confident	67 Å²	67	32.9 Å²	32.9	35%	0.351	18%	0.176	S	C	.	.	H	α-helix	trans	-75.6	-25.1	177.6	-70.9	171.1	0	0	0	113.1	V269 A308 N309 V315 L316	V269-L312 HydrophobicContact CG1-CD1 3.98Å; A308-L312 WeakPolarHBondContact O-CB 3.4Å; A308-L312 VanDerWaalsContact O-CG 3.22Å; A308-L312 WeakPolarHBondContact O-CG 3.49Å; A308-L312 PolarHBondContact O-N 2.9Å; N309-L312 PolarHBondContact O-N 3.48Å; L312-V315 WeakPolarHBondContact O-CB 3.45Å; L312-V315 PolarHBondContact O-N 2.85Å; L312-V315 VanDerWaalsContact O-N 3.12Å; L312-L316 WeakPolarHBondContact O-CG 3.31Å; L312-L316 PolarHBondContact O-N 3.33Å
313	N	81.6	Confident	77	Confident	4 Å²	4	37.6 Å²	37.6	2%	0.021	20%	0.201	C	C	.	.	H	α-helix	trans	-55.3	-52.5	-177.6	-72.3	-32	0	0	0	113.7	L91 D95 N309 V315 L316 Y317	L91-N313 HydrophobicContact CD2-CB 4.29Å; D95-N313 PolarHBondContact OD2-ND2 2.89Å; N309-N313 PolarHBondContact O-N 3.33Å; N309-N313 PolarHBondContact O-ND2 2.94Å; N313-V315 VanDerWaalsContact C-N 3.3Å; N313-V315 PolarHBondContact O-N 3.04Å; N313-L316 PolarHBondContact O-N 3.21Å; N313-Y317 HydrophobicContact CB-CE2 4.14Å; N313-Y317 WeakPolarHBondContact O-CD2 3.48Å; N313-Y317 PolarHBondContact O-N 3.41Å
314	P	77.2	Confident	76	Confident	10 Å²	10	36.4 Å²	36.4	7%	0.065	19%	0.193	C	C	.	.	H	α-helix	trans	-58.4	-37.5	174.2	-26.1	34.3	0	0	0	114.1	G66 N67 V70 Y317 A318	G66-P314 VanDerWaalsContact C-CG 3.43Å; N67-P314 HydrophobicContact CB-CG 4.38Å; N67-P314 VanDerWaalsContact OD1-CG 3.31Å; N67-P314 WeakPolarHBondContact OD1-CG 3.38Å; V70-P314 HydrophobicContact CG2-CB 4.01Å; V70-P314 HydrophobicContact CG2-CG 4.27Å; P314-Y317 PolarHBondContact O-N 2.93Å; P314-A318 VanDerWaalsContact O-CB 3.22Å; P314-A318 WeakPolarHBondContact O-CB 3.33Å; P314-A318 PolarHBondContact O-N 3.09Å
315	V	73.8	Confident	75.2	Confident	57 Å²	57	39.4 Å²	39.4	35%	0.345	20%	0.204	S	C	.	.	H	α-helix	trans	-63.3	-47.4	178.1	178.9	0	0	0	0	109.4	L312 N313 Y317 A318 F319	L312-V315 WeakPolarHBondContact O-CB 3.45Å; L312-V315 PolarHBondContact O-N 2.85Å; L312-V315 VanDerWaalsContact O-N 3.12Å; N313-V315 VanDerWaalsContact C-N 3.3Å; N313-V315 PolarHBondContact O-N 3.04Å; V315-Y317 VanDerWaalsContact C-N 3.35Å; V315-Y317 PolarHBondContact O-N 3.45Å; V315-A318 PolarHBondContact O-N 2.89Å; V315-F319 HydrophobicContact CG1-CD2 3.62Å; V315-F319 HydrophobicContact CG1-CE2 3.66Å; V315-F319 WeakPolarHBondContact O-CD2 3.5Å; V315-F319 PolarHBondContact O-N 3.17Å
316	L	72.6	Confident	74.2	Confident	23 Å²	23	39.3 Å²	39.3	12%	0.12	21%	0.21	C	C	.	.	H	α-helix	trans	-58.8	-45.2	176	-67.1	171.8	0	0	0	111.3	V265 V266 V269 L312 N313 F319 L320	V265-L316 HydrophobicContact CG1-CD2 3.79Å; V266-L316 HydrophobicContact CG2-CD1 4.35Å; V269-L316 HydrophobicContact CB-CD1 4.45Å; V269-L316 HydrophobicContact CG1-CD1 4.3Å; V269-L316 HydrophobicContact CG2-CD1 4.4Å; L312-L316 WeakPolarHBondContact O-CG 3.31Å; L312-L316 PolarHBondContact O-N 3.33Å; N313-L316 PolarHBondContact O-N 3.21Å; L316-F319 PolarHBondContact O-N 2.99Å; L316-L320 HydrophobicContact CB-CD1 3.97Å; L316-L320 HydrophobicContact CD2-CD1 4.07Å; L316-L320 WeakPolarHBondContact O-CB 3.32Å; L316-L320 WeakPolarHBondContact O-CD1 3.42Å; L316-L320 WeakPolarHBondContact O-CG 3.43Å; L316-L320 PolarHBondContact O-N 2.91Å
317	Y	69.3	Low	73.2	Confident	11 Å²	11	39.9 Å²	39.9	4%	0.043	21%	0.213	C	C	.	.	H	α-helix	trans	-64.7	-43.2	176.6	-56.8	-40.4	0	0	0	112.7	V70 I88 L91 M142 N313 P314 V315 F319 L320 D321	V70-Y317 HydrophobicContact CG2-CD2 4.42Å; I88-Y317 HydrophobicContact CB-CE2 4.49Å; I88-Y317 HydrophobicContact CD1-CD1 4.26Å; I88-Y317 HydrophobicContact CD1-CE1 4.1Å; I88-Y317 HydrophobicContact CG1-CE1 4.1Å; I88-Y317 HydrophobicContact CG1-CE2 4.38Å; I88-Y317 HydrophobicContact CG2-CD2 3.89Å; I88-Y317 HydrophobicContact CG2-CE2 3.57Å; L91-Y317 WeakPolarHBondContact CD2-OH 3.32Å; M142-Y317 HydrophobicContact CE-CE1 4.42Å; N313-Y317 HydrophobicContact CB-CE2 4.14Å; N313-Y317 WeakPolarHBondContact O-CD2 3.48Å; N313-Y317 PolarHBondContact O-N 3.41Å; P314-Y317 PolarHBondContact O-N 2.93Å; V315-Y317 VanDerWaalsContact C-N 3.35Å; V315-Y317 PolarHBondContact O-N 3.45Å; Y317-F319 VanDerWaalsContact C-N 3.28Å; Y317-F319 PolarHBondContact O-N 3.49Å; Y317-L320 PolarHBondContact O-N 3.3Å; Y317-D321 PolarHBondContact O-N 3.49Å
318	A	67	Low	72.3	Confident	29 Å²	29	41.8 Å²	41.8	24%	0.24	22%	0.222	C	C	.	.	H	α-helix	trans	-63.5	-30.6	177.5	0	0	0	0	0	112.7	P314 V315 F324 K325	P314-A318 VanDerWaalsContact O-CB 3.22Å; P314-A318 WeakPolarHBondContact O-CB 3.33Å; P314-A318 PolarHBondContact O-N 3.09Å; V315-A318 PolarHBondContact O-N 2.89Å; A318-F324 HydrophobicContact CB-CD1 4.35Å; A318-F324 HydrophobicContact CB-CE1 4.29Å; A318-K325 WeakPolarHBondContact O-CD 3.45Å; A318-K325 WeakPolarHBondContact O-CE 3.21Å; A318-K325 WeakPolarHBondContact O-CG 3.5Å
319	F	63.3	Low	71.3	Confident	141 Å²	141	47.7 Å²	47.7	62%	0.618	25%	0.245	S	C	*	.	H	α-helix	trans	-87.4	-27.7	176.2	-80.2	-73.9	0	0	0	113.6	V315 L316 Y317 K325	V315-F319 HydrophobicContact CG1-CD2 3.62Å; V315-F319 HydrophobicContact CG1-CE2 3.66Å; V315-F319 WeakPolarHBondContact O-CD2 3.5Å; V315-F319 PolarHBondContact O-N 3.17Å; L316-F319 PolarHBondContact O-N 2.99Å; Y317-F319 VanDerWaalsContact C-N 3.28Å; Y317-F319 PolarHBondContact O-N 3.49Å; F319-K325 VanDerWaalsContact C-CE 3.49Å; F319-K325 WeakPolarHBondContact O-CE 3.48Å; F319-K325 PolarHBondContact O-NZ 3.17Å
320	L	59.5	Low	70.2	Confident	33 Å²	33	51.8 Å²	51.8	17%	0.173	26%	0.262	C	S	.	.	H	α-helix	trans	-104.9	-30.3	-165.7	-58.2	163.7	0	0	0	114	M262 L316 Y317	M262-L320 HydrophobicContact CB-CB 4.27Å; M262-L320 HydrophobicContact CB-CD1 4.27Å; M262-L320 HydrophobicContact CB-CD2 3.96Å; M262-L320 HydrophobicContact CB-CG 4.37Å; M262-L320 HydrophobicContact CE-CB 3.61Å; M262-L320 HydrophobicContact CE-CD1 4.32Å; M262-L320 HydrophobicContact CG-CB 3.62Å; M262-L320 HydrophobicContact CG-CD1 3.61Å; M262-L320 HydrophobicContact CG-CD2 4.1Å; M262-L320 HydrophobicContact CG-CG 3.94Å; M262-L320 HydrophobicContact SD-CB 3.52Å; M262-L320 VanDerWaalsContact SD-CB 3.52Å; M262-L320 HydrophobicContact SD-CG 4.48Å; L316-L320 HydrophobicContact CB-CD1 3.97Å; L316-L320 HydrophobicContact CD2-CD1 4.07Å; L316-L320 WeakPolarHBondContact O-CB 3.32Å; L316-L320 WeakPolarHBondContact O-CD1 3.42Å; L316-L320 WeakPolarHBondContact O-CG 3.43Å; L316-L320 PolarHBondContact O-N 2.91Å; Y317-L320 PolarHBondContact O-N 3.3Å
321	D	65.1	Low	69.2	Low	33 Å²	33	56 Å²	56	18%	0.176	28%	0.281	C	S	.	.			trans	-101.9	115.6	179.3	-170.7	-26.9	0	0	0	112.2	Y317 N323 F324 K325	Y317-D321 PolarHBondContact O-N 3.49Å; D321-N323 WeakPolarHBondContact OD1-CA 3.18Å; D321-N323 WeakPolarHBondContact OD1-CB 3.48Å; D321-N323 PolarHBondContact OD1-N 3.4Å; D321-F324 HydrophobicContact CB-CB 3.74Å; D321-F324 PolarHBondContact O-N 3.14Å; D321-F324 PolarHBondContact OD1-N 3.27Å; D321-K325 WeakPolarHBondContact O-CG 3.45Å; D321-K325 PolarHBondContact O-N 2.72Å
322	E	64.9	Low	68.3	Low	112 Å²	112	58.2 Å²	58.2	52%	0.523	30%	0.295	S	S	.	.	H	α-helix	trans	-70.6	-30	179.8	-60.5	-152	158.1	0	0	113.8	R258 F324 K325 A326	R258-E322 IonicContact CZ-OE1 2.77Å; R258-E322 VanDerWaalsContact NH1-CD 3.25Å; R258-E322 IonicContact NH1-OE1 3.27Å; R258-E322 PolarHBondContact NH1-OE1 2.98Å; R258-E322 IonicContact NH1-OE2 3.42Å; R258-E322 IonicContact NH2-OE1 3.5Å; R258-E322 PolarHBondContact NH2-OE1 3.3Å; E322-F324 VanDerWaalsContact C-N 3.31Å; E322-K325 PolarHBondContact O-N 3.22Å; E322-A326 VanDerWaalsContact O-CB 3.31Å; E322-A326 WeakPolarHBondContact O-CB 3.26Å; E322-A326 PolarHBondContact O-N 3.44Å
323	N	62.3	Low	67.5	Low	111 Å²	111	61.3 Å²	61.3	59%	0.594	31%	0.306	S	S	*	.	H	α-helix	trans	-69.2	-38	174.5	-63.8	-48.8	0	0	0	110	M80 D321 A326 C327	M80-N323 HydrophobicContact SD-CB 4.43Å; D321-N323 WeakPolarHBondContact OD1-CA 3.18Å; D321-N323 WeakPolarHBondContact OD1-CB 3.48Å; D321-N323 PolarHBondContact OD1-N 3.4Å; N323-A326 PolarHBondContact O-N 2.81Å; N323-C327 WeakPolarHBondContact O-CB 3.42Å; N323-C327 PolarHBondContact O-N 3.07Å; N323-C327 PolarHBondContact O-SG 3.14Å
324	F	63.8	Low	66.3	Low	9 Å²	9	65.2 Å²	65.2	4%	0.039	33%	0.332	C	S	.	.	H	α-helix	trans	-64.7	-47.9	172.9	-165.9	-91	0	0	0	111	V70 V73 M80 A318 D321 E322 A326 C327 F328	V70-F324 HydrophobicContact CB-CE2 4.26Å; V70-F324 HydrophobicContact CB-CZ 4.21Å; V70-F324 HydrophobicContact CG1-CE2 4.28Å; V70-F324 HydrophobicContact CG2-CE1 4.42Å; V70-F324 HydrophobicContact CG2-CE2 3.89Å; V70-F324 HydrophobicContact CG2-CZ 3.46Å; V70-F324 VanDerWaalsContact CG2-CZ 3.46Å; V73-F324 HydrophobicContact CB-CE2 4.49Å; V73-F324 HydrophobicContact CG1-CE2 4.33Å; M80-F324 HydrophobicContact CE-CD2 4.06Å; A318-F324 HydrophobicContact CB-CD1 4.35Å; A318-F324 HydrophobicContact CB-CE1 4.29Å; D321-F324 HydrophobicContact CB-CB 3.74Å; D321-F324 PolarHBondContact O-N 3.14Å; D321-F324 PolarHBondContact OD1-N 3.27Å; E322-F324 VanDerWaalsContact C-N 3.31Å; F324-A326 VanDerWaalsContact C-N 3.32Å; F324-A326 PolarHBondContact O-N 3.29Å; F324-C327 PolarHBondContact O-N 2.79Å; F324-F328 HydrophobicContact CD1-CB 4.47Å; F324-F328 HydrophobicContact CE1-CB 4.38Å; F324-F328 HydrophobicContact CE1-CD2 4.23Å; F324-F328 WeakPolarHBondContact O-CB 3.46Å; F324-F328 PolarHBondContact O-N 3.4Å
325	K	68.2	Low	65.1	Low	72 Å²	72	70.2 Å²	70.2	31%	0.313	36%	0.362	S	S	.	.	H	α-helix	trans	-54.3	-45.8	173.1	-75.7	-178.9	-176.9	177.5	0	112.6	A318 F319 D321 E322 F328 K329	A318-K325 WeakPolarHBondContact O-CD 3.45Å; A318-K325 WeakPolarHBondContact O-CE 3.21Å; A318-K325 WeakPolarHBondContact O-CG 3.5Å; F319-K325 VanDerWaalsContact C-CE 3.49Å; F319-K325 WeakPolarHBondContact O-CE 3.48Å; F319-K325 PolarHBondContact O-NZ 3.17Å; D321-K325 WeakPolarHBondContact O-CG 3.45Å; D321-K325 PolarHBondContact O-N 2.72Å; E322-K325 PolarHBondContact O-N 3.22Å; K325-F328 PolarHBondContact O-N 2.81Å; K325-K329 WeakPolarHBondContact O-CB 3.36Å; K325-K329 WeakPolarHBondContact O-CG 2.88Å; K325-K329 PolarHBondContact O-N 2.98Å
326	A	65.3	Low	64.1	Low	45 Å²	45	70.4 Å²	70.4	37%	0.372	37%	0.37	S	S	.	.	H	α-helix	trans	-66	-42	-178.6	0	0	0	0	0	111.8	E322 N323 F324 K330	E322-A326 VanDerWaalsContact O-CB 3.31Å; E322-A326 WeakPolarHBondContact O-CB 3.26Å; E322-A326 PolarHBondContact O-N 3.44Å; N323-A326 PolarHBondContact O-N 2.81Å; F324-A326 VanDerWaalsContact C-N 3.32Å; F324-A326 PolarHBondContact O-N 3.29Å; A326-K330 VanDerWaalsContact O-CG 3.3Å; A326-K330 WeakPolarHBondContact O-CG 3.22Å; A326-K330 PolarHBondContact O-N 3.48Å
327	C	65.4	Low	62.9	Low	18 Å²	18	72.9 Å²	72.9	12%	0.122	38%	0.38	C	S	.	.	H	α-helix	trans	-71.3	-37.8	176.5	-63.2	0	0	0	0	112.1	V73 F77 N323 F324 K330 F331	V73-C327 HydrophobicContact CG1-CB 3.81Å; F77-C327 HydrophobicContact CD2-CB 4.18Å; F77-C327 HydrophobicContact CE2-CB 4.13Å; N323-C327 WeakPolarHBondContact O-CB 3.42Å; N323-C327 PolarHBondContact O-N 3.07Å; N323-C327 PolarHBondContact O-SG 3.14Å; F324-C327 PolarHBondContact O-N 2.79Å; C327-K330 WeakPolarHBondContact O-CB 3.33Å; C327-K330 PolarHBondContact O-N 3.46Å; C327-F331 PolarHBondContact O-N 2.94Å; C327-F331 VanDerWaalsContact O-N 3.09Å
328	F	67.3	Low	62	Low	71 Å²	71	81.6 Å²	81.6	31%	0.311	41%	0.413	S	S	.	.	H	α-helix	trans	-66.9	-41.6	176.5	-168.6	-98.2	0	0	0	111.6	F324 K325 K330 F331 C332	F324-F328 HydrophobicContact CD1-CB 4.47Å; F324-F328 HydrophobicContact CE1-CB 4.38Å; F324-F328 HydrophobicContact CE1-CD2 4.23Å; F324-F328 WeakPolarHBondContact O-CB 3.46Å; F324-F328 PolarHBondContact O-N 3.4Å; K325-F328 PolarHBondContact O-N 2.81Å; F328-K330 VanDerWaalsContact C-N 3.3Å; F328-K330 PolarHBondContact O-N 3.02Å; F328-F331 WeakPolarHBondContact O-CA 3.38Å; F328-F331 WeakPolarHBondContact O-CB 3.13Å; F328-F331 PolarHBondContact O-N 2.99Å; F328-C332 WeakPolarHBondContact CE1-SG 3.38Å; F328-C332 VanDerWaalsContact CZ-SG 3.57Å; F328-C332 PolarHBondContact O-N 3.44Å
329	K	66.6	Low	61.2	Low	142 Å²	142	84 Å²	84	62%	0.617	42%	0.424	S	S	*	.	H	α-helix	trans	-59.3	-39.5	171	-80.5	-175.7	177.8	-172.5	0	112.3	K325 F331 F333	K325-K329 WeakPolarHBondContact O-CB 3.36Å; K325-K329 WeakPolarHBondContact O-CG 2.88Å; K325-K329 PolarHBondContact O-N 2.98Å; K329-F331 PolarHBondContact O-N 3.38Å; K329-F333 PolarHBondContact O-N 3.39Å
330	K	64.3	Low	60.8	Low	88 Å²	88	83.7 Å²	83.7	38%	0.383	43%	0.425	S	S	.	.	H	α-helix	trans	-64.6	-28.9	174.6	-73	173	-176.8	-177.9	0	112.9	A326 C327 F328 F337	A326-K330 VanDerWaalsContact O-CG 3.3Å; A326-K330 WeakPolarHBondContact O-CG 3.22Å; A326-K330 PolarHBondContact O-N 3.48Å; C327-K330 WeakPolarHBondContact O-CB 3.33Å; C327-K330 PolarHBondContact O-N 3.46Å; F328-K330 VanDerWaalsContact C-N 3.3Å; F328-K330 PolarHBondContact O-N 3.02Å; K330-F337 HydrophobicContact CD-CD2 3.91Å; K330-F337 HydrophobicContact CD-CE2 3.92Å; K330-F337 HydrophobicContact CG-CD2 3.87Å; K330-F337 HydrophobicContact CG-CE2 4.4Å; K330-F337 HydrophobicContact CG-CG 4.31Å
331	F	64.9	Low	60.6	Low	89 Å²	89	86.1 Å²	86.1	39%	0.39	44%	0.438	S	S	.	.	H	α-helix	trans	-78.4	-49.3	175.2	176.9	-107	0	0	0	112.1	Y72 C327 F328 K329 F333	Y72-F331 HydrophobicContact CD1-CD2 4.13Å; Y72-F331 AromaticContact CD1-CE2 3.94Å; Y72-F331 HydrophobicContact CD1-CE2 3.94Å; Y72-F331 AromaticContact CE1-CD2 3.6Å; Y72-F331 HydrophobicContact CE1-CD2 3.6Å; Y72-F331 AromaticContact CE1-CE2 3.51Å; Y72-F331 HydrophobicContact CE1-CE2 3.51Å; Y72-F331 HydrophobicContact CE1-CZ 4.48Å; C327-F331 PolarHBondContact O-N 2.94Å; C327-F331 VanDerWaalsContact O-N 3.09Å; F328-F331 WeakPolarHBondContact O-CA 3.38Å; F328-F331 WeakPolarHBondContact O-CB 3.13Å; F328-F331 PolarHBondContact O-N 2.99Å; K329-F331 PolarHBondContact O-N 3.38Å; F331-F333 PolarHBondContact O-N 3.49Å
332	C	68	Low	60	Low	57 Å²	57	90 Å²	90	39%	0.385	46%	0.455	S	S	.	.	H	α-helix	trans	-72.7	-25.5	-178.3	-63.7	0	0	0	0	113.7	F328	F328-C332 WeakPolarHBondContact CE1-SG 3.38Å; F328-C332 VanDerWaalsContact CZ-SG 3.57Å; F328-C332 PolarHBondContact O-N 3.44Å
333	F	66.9	Low	59.4	Low	133 Å²	133	90.4 Å²	90.4	58%	0.583	46%	0.458	S	S	*	.			trans	-129.6	74.7	-179.9	-57.5	-79.9	0	0	0	111.6	K329 F331 T335	K329-F333 PolarHBondContact O-N 3.39Å; F331-F333 PolarHBondContact O-N 3.49Å; F333-T335 PolarHBondContact O-N 2.84Å
334	P	56.6	Low	59.6	Low	85 Å²	85	88.5 Å²	88.5	55%	0.552	45%	0.453	S	S	*	.	H	α-helix	trans	-60.6	-30.5	-179.4	-20.1	31.3	0	0	0	113.2	F337 R338	P334-F337 PolarHBondContact O-N 3.39Å; P334-R338 PolarHBondContact O-N 2.96Å
335	T	52.7	Low	59.4	Low	115 Å²	115	92.9 Å²	92.9	71%	0.706	48%	0.477	S	S	*	.	H	α-helix	trans	-70.4	-37.8	-172.9	-21	0	0	0	0	112.8	F333 F337 R338 T339	F333-T335 PolarHBondContact O-N 2.84Å; T335-F337 VanDerWaalsContact C-N 3.32Å; T335-F337 PolarHBondContact O-N 2.84Å; T335-R338 PolarHBondContact O-N 3.39Å; T335-T339 PolarHBondContact O-OG1 2.96Å; T335-T339 VanDerWaalsContact O-OG1 3.14Å
336	A	51.3	Low	59.4	Low	62 Å²	62	97.9 Å²	97.9	51%	0.512	49%	0.494	S	S	.	.	H	α-helix	trans	-68.1	-33	177.3	0	0	0	0	0	112.1	T339 E340	A336-T339 PolarHBondContact O-N 2.9Å; A336-E340 PolarHBondContact O-N 3.31Å; A336-E340 VanDerWaalsContact O-N 3.13Å
337	F	48.1	Very low	59.4	Low	75 Å²	75	101.9 Å²	101.9	33%	0.329	51%	0.507	S	S	.	.	H	α-helix	trans	-72.3	-34.5	178.3	-177.3	-107.3	0	0	0	112.8	K330 P334 T335 T339 E340 L341	K330-F337 HydrophobicContact CD-CD2 3.91Å; K330-F337 HydrophobicContact CD-CE2 3.92Å; K330-F337 HydrophobicContact CG-CD2 3.87Å; K330-F337 HydrophobicContact CG-CE2 4.4Å; K330-F337 HydrophobicContact CG-CG 4.31Å; P334-F337 PolarHBondContact O-N 3.39Å; T335-F337 VanDerWaalsContact C-N 3.32Å; T335-F337 PolarHBondContact O-N 2.84Å; F337-T339 VanDerWaalsContact C-N 3.25Å; F337-T339 PolarHBondContact O-N 3.43Å; F337-E340 PolarHBondContact O-N 3.16Å; F337-L341 HydrophobicContact CE1-CD2 4.32Å; F337-L341 HydrophobicContact CZ-CD1 4.16Å; F337-L341 WeakPolarHBondContact O-CB 3.28Å; F337-L341 PolarHBondContact O-N 2.99Å
338	R	49.4	Very low	59.7	Low	194 Å²	194	104.6 Å²	104.6	73%	0.732	53%	0.525	S	S	*	.	H	α-helix	trans	-62.1	-37.7	175.5	-149.4	179.8	-166.5	-153	3.9	111.1	P334 T335 Q342	P334-R338 PolarHBondContact O-N 2.96Å; T335-R338 PolarHBondContact O-N 3.39Å; R338-Q342 WeakPolarHBondContact O-CB 3.3Å; R338-Q342 PolarHBondContact O-N 3.25Å
339	T	51.6	Low	59.9	Low	78 Å²	78	104.2 Å²	104.2	48%	0.479	53%	0.531	S	S	.	.	H	α-helix	trans	-71.6	-44.4	177.4	-40.1	0	0	0	0	112.3	T335 A336 F337 Q342 M343	T335-T339 PolarHBondContact O-OG1 2.96Å; T335-T339 VanDerWaalsContact O-OG1 3.14Å; A336-T339 PolarHBondContact O-N 2.9Å; F337-T339 VanDerWaalsContact C-N 3.25Å; F337-T339 PolarHBondContact O-N 3.43Å; T339-Q342 PolarHBondContact O-N 3Å; T339-M343 WeakPolarHBondContact O-CG 3.28Å; T339-M343 PolarHBondContact O-N 3.41Å
340	E	55.1	Low	60.5	Low	136 Å²	136	102.4 Å²	102.4	64%	0.636	53%	0.527	S	S	*	.	H	α-helix	trans	-64.2	-41	175.5	-85.1	-166.5	165.9	0	0	112.8	A336 F337 M343 S344	A336-E340 PolarHBondContact O-N 3.31Å; A336-E340 VanDerWaalsContact O-N 3.13Å; F337-E340 PolarHBondContact O-N 3.16Å; E340-M343 PolarHBondContact O-N 2.92Å; E340-S344 WeakPolarHBondContact O-CB 3.35Å; E340-S344 PolarHBondContact O-N 3.24Å
341	L	55	Low	61	Low	83 Å²	83	101.1 Å²	101.1	44%	0.435	53%	0.533	S	S	.	.	H	α-helix	trans	-69	-36.6	178.1	-160.6	75.4	0	0	0	111.4	F337 N345	F337-L341 HydrophobicContact CE1-CD2 4.32Å; F337-L341 HydrophobicContact CZ-CD1 4.16Å; F337-L341 WeakPolarHBondContact O-CB 3.28Å; F337-L341 PolarHBondContact O-N 2.99Å; L341-N345 VanDerWaalsContact O-CB 3.29Å; L341-N345 WeakPolarHBondContact O-CB 3.42Å; L341-N345 VanDerWaalsContact O-CG 3.28Å; L341-N345 PolarHBondContact O-N 3.15Å; L341-N345 PolarHBondContact O-ND2 3.33Å
342	Q	51.7	Low	61.5	Low	114 Å²	114	103.4 Å²	103.4	53%	0.533	54%	0.543	S	S	.	.	H	α-helix	trans	-64.2	-42.4	170.6	-93.6	-178.6	-46.6	0	0	112.2	R338 T339 R346	R338-Q342 WeakPolarHBondContact O-CB 3.3Å; R338-Q342 PolarHBondContact O-N 3.25Å; T339-Q342 PolarHBondContact O-N 3Å; Q342-R346 VanDerWaalsContact O-CB 3.31Å; Q342-R346 WeakPolarHBondContact O-CB 3.32Å; Q342-R346 VanDerWaalsContact O-CG 3.3Å; Q342-R346 WeakPolarHBondContact O-CG 3.39Å; Q342-R346 PolarHBondContact O-N 3.36Å
343	M	53.9	Low	62	Low	122 Å²	122	105.2 Å²	105.2	60%	0.601	55%	0.548	S	S	*	.	H	α-helix	trans	-67	-42.1	177.1	-74.4	-166.9	81.2	0	0	112	T339 E340 R346 M347	T339-M343 WeakPolarHBondContact O-CG 3.28Å; T339-M343 PolarHBondContact O-N 3.41Å; E340-M343 PolarHBondContact O-N 2.92Å; M343-R346 PolarHBondContact O-N 3.5Å; M343-M347 WeakPolarHBondContact O-CG 3.36Å; M343-M347 PolarHBondContact O-N 3.49Å
344	S	65.6	Low	62.6	Low	70 Å²	70	102.7 Å²	102.7	49%	0.49	54%	0.544	S	S	.	.	H	α-helix	trans	-65.5	-42.6	177.7	-175.3	0	0	0	0	112.3	E340 M347 C348	E340-S344 WeakPolarHBondContact O-CB 3.35Å; E340-S344 PolarHBondContact O-N 3.24Å; S344-M347 PolarHBondContact O-N 2.99Å; S344-C348 WeakPolarHBondContact O-CB 3.48Å; S344-C348 PolarHBondContact O-N 2.88Å
345	N	60.3	Low	63.4	Low	102 Å²	102	101.4 Å²	101.4	55%	0.545	54%	0.541	S	S	.	.	H	α-helix	trans	-66.6	-37.8	174.7	-75.5	-19.6	0	0	0	112.2	L341 C348 S349	L341-N345 VanDerWaalsContact O-CB 3.29Å; L341-N345 WeakPolarHBondContact O-CB 3.42Å; L341-N345 VanDerWaalsContact O-CG 3.28Å; L341-N345 PolarHBondContact O-N 3.15Å; L341-N345 PolarHBondContact O-ND2 3.33Å; N345-C348 PolarHBondContact O-N 3.5Å; N345-S349 PolarHBondContact O-N 3.23Å
346	R	66.6	Low	64.3	Low	177 Å²	177	103.7 Å²	103.7	67%	0.668	54%	0.537	S	S	*	.	H	α-helix	trans	-63	-45.3	173	-82.5	-180	171.2	-174.4	-2.3	111.8	Q342 M343 C348 S349 I350	Q342-R346 VanDerWaalsContact O-CB 3.31Å; Q342-R346 WeakPolarHBondContact O-CB 3.32Å; Q342-R346 VanDerWaalsContact O-CG 3.3Å; Q342-R346 WeakPolarHBondContact O-CG 3.39Å; Q342-R346 PolarHBondContact O-N 3.36Å; M343-R346 PolarHBondContact O-N 3.5Å; R346-C348 VanDerWaalsContact C-N 3.32Å; R346-C348 PolarHBondContact O-N 3.29Å; R346-S349 WeakPolarHBondContact O-CB 3.38Å; R346-S349 PolarHBondContact O-N 2.98Å; R346-I350 VanDerWaalsContact O-CG1 3.26Å; R346-I350 WeakPolarHBondContact O-CG1 3.26Å; R346-I350 PolarHBondContact O-N 3.07Å
347	M	67.1	Low	65.4	Low	129 Å²	129	103.7 Å²	103.7	64%	0.635	54%	0.537	S	S	*	.	H	α-helix	trans	-61.7	-39.7	175.8	-77.3	173.6	48.2	0	0	112.4	M343 S344 I350 A351	M343-M347 WeakPolarHBondContact O-CG 3.36Å; M343-M347 PolarHBondContact O-N 3.49Å; S344-M347 PolarHBondContact O-N 2.99Å; M347-I350 PolarHBondContact O-N 3.36Å; M347-A351 WeakPolarHBondContact O-CB 3.43Å; M347-A351 PolarHBondContact O-N 3.3Å
348	C	70.1	Confident	66.4	Low	74 Å²	74	103.7 Å²	103.7	50%	0.5	55%	0.546	S	S	.	.	H	α-helix	trans	-69.3	-33.7	178	-153.6	0	0	0	0	112.2	S344 N345 R346 K352	S344-C348 WeakPolarHBondContact O-CB 3.48Å; S344-C348 PolarHBondContact O-N 2.88Å; N345-C348 PolarHBondContact O-N 3.5Å; R346-C348 VanDerWaalsContact C-N 3.32Å; R346-C348 PolarHBondContact O-N 3.29Å; C348-K352 WeakPolarHBondContact O-CG 3.35Å; C348-K352 PolarHBondContact O-N 3.4Å
349	S	72.4	Confident	67.5	Low	63 Å²	63	101.8 Å²	101.8	44%	0.441	54%	0.543	S	S	.	.	H	α-helix	trans	-64.6	-50.7	170.5	-166.5	0	0	0	0	111.2	N345 R346 A351 K352 D353	N345-S349 PolarHBondContact O-N 3.23Å; R346-S349 WeakPolarHBondContact O-CB 3.38Å; R346-S349 PolarHBondContact O-N 2.98Å; S349-A351 VanDerWaalsContact C-N 3.3Å; S349-A351 PolarHBondContact O-N 2.76Å; S349-K352 WeakPolarHBondContact O-CB 3.35Å; S349-K352 PolarHBondContact O-N 2.97Å; S349-D353 VanDerWaalsContact O-CG 3.25Å; S349-D353 PolarHBondContact O-N 3.41Å
350	I	78.1	Confident	68.1	Low	105 Å²	105	103.5 Å²	103.5	54%	0.538	55%	0.549	S	S	.	.	H	α-helix	trans	-59.4	-42.4	179.5	-67.3	164.1	0	0	0	110.8	R346 M347 K352 D353 V354	R346-I350 VanDerWaalsContact O-CG1 3.26Å; R346-I350 WeakPolarHBondContact O-CG1 3.26Å; R346-I350 PolarHBondContact O-N 3.07Å; M347-I350 PolarHBondContact O-N 3.36Å; I350-K352 VanDerWaalsContact C-N 3.3Å; I350-K352 PolarHBondContact O-N 3.34Å; I350-D353 PolarHBondContact O-N 2.98Å; I350-V354 HydrophobicContact CG2-CG2 4.31Å; I350-V354 WeakPolarHBondContact O-CB 3.39Å; I350-V354 VanDerWaalsContact O-CG2 3.25Å; I350-V354 WeakPolarHBondContact O-CG2 3.32Å; I350-V354 PolarHBondContact O-N 3.11Å
351	A	75.1	Confident	68.3	Low	61 Å²	61	100.9 Å²	100.9	50%	0.504	55%	0.546	S	S	.	.	H	α-helix	trans	-62.9	-36	177	0	0	0	0	0	112.7	M347 S349 A355	M347-A351 WeakPolarHBondContact O-CB 3.43Å; M347-A351 PolarHBondContact O-N 3.3Å; S349-A351 VanDerWaalsContact C-N 3.3Å; S349-A351 PolarHBondContact O-N 2.76Å; A351-A355 WeakPolarHBondContact O-CB 3.27Å; A351-A355 PolarHBondContact O-N 2.93Å
352	K	76.2	Confident	68.4	Low	136 Å²	136	104.7 Å²	104.7	59%	0.591	56%	0.562	S	S	*	*	H	α-helix	trans	-68.5	-44	173.6	-77	178.5	178.7	-179.6	0	111.5	C348 S349 I350 V354 A355 Y356	C348-K352 WeakPolarHBondContact O-CG 3.35Å; C348-K352 PolarHBondContact O-N 3.4Å; S349-K352 WeakPolarHBondContact O-CB 3.35Å; S349-K352 PolarHBondContact O-N 2.97Å; I350-K352 VanDerWaalsContact C-N 3.3Å; I350-K352 PolarHBondContact O-N 3.34Å; K352-V354 VanDerWaalsContact C-N 3.33Å; K352-V354 PolarHBondContact O-N 3.47Å; K352-A355 PolarHBondContact O-N 2.93Å; K352-Y356 WeakPolarHBondContact O-CD2 3.33Å; K352-Y356 PolarHBondContact O-N 3.14Å
353	D	78	Confident	68.6	Low	95 Å²	95	102.6 Å²	102.6	51%	0.508	57%	0.57	S	S	.	*	H	α-helix	trans	-63.7	-40.4	179.9	-62.3	-29	0	0	0	111.2	S349 I350 Y356 A357	S349-D353 VanDerWaalsContact O-CG 3.25Å; S349-D353 PolarHBondContact O-N 3.41Å; I350-D353 PolarHBondContact O-N 2.98Å; D353-Y356 PolarHBondContact O-N 3.08Å; D353-A357 WeakPolarHBondContact O-CB 3.44Å; D353-A357 PolarHBondContact O-N 3.4Å
354	V	79.1	Confident	68.6	Low	80 Å²	80	102 Å²	102	49%	0.485	57%	0.574	S	S	.	*	H	α-helix	trans	-64.5	-43	173.4	172.7	0	0	0	0	111.4	I350 K352 Y356 A357 C358	I350-V354 HydrophobicContact CG2-CG2 4.31Å; I350-V354 WeakPolarHBondContact O-CB 3.39Å; I350-V354 VanDerWaalsContact O-CG2 3.25Å; I350-V354 WeakPolarHBondContact O-CG2 3.32Å; I350-V354 PolarHBondContact O-N 3.11Å; K352-V354 VanDerWaalsContact C-N 3.33Å; K352-V354 PolarHBondContact O-N 3.47Å; V354-Y356 VanDerWaalsContact C-N 3.34Å; V354-Y356 PolarHBondContact O-N 3.42Å; V354-A357 PolarHBondContact O-N 2.74Å; V354-C358 PolarHBondContact O-N 3.32Å; V354-C358 PolarHBondContact O-SG 3.25Å
355	A	73.9	Confident	67.8	Low	59 Å²	59	104.9 Å²	104.9	49%	0.488	58%	0.584	S	S	.	*	H	α-helix	trans	-63.9	-37.8	177.1	0	0	0	0	0	112.5	A351 K352 K359	A351-A355 WeakPolarHBondContact O-CB 3.27Å; A351-A355 PolarHBondContact O-N 2.93Å; K352-A355 PolarHBondContact O-N 2.93Å; A355-K359 WeakPolarHBondContact O-CB 3.38Å; A355-K359 PolarHBondContact O-N 3.11Å; A355-K359 VanDerWaalsContact O-N 3.11Å
356	Y	72.4	Confident	67.4	Low	162 Å²	162	107.6 Å²	107.6	64%	0.635	60%	0.598	S	S	*	*	H	α-helix	trans	-66.4	-41.2	173.3	-92.8	-77.9	0	0	0	112.2	K352 D353 V354 K359 N360	K352-Y356 WeakPolarHBondContact O-CD2 3.33Å; K352-Y356 PolarHBondContact O-N 3.14Å; D353-Y356 PolarHBondContact O-N 3.08Å; V354-Y356 VanDerWaalsContact C-N 3.34Å; V354-Y356 PolarHBondContact O-N 3.42Å; Y356-K359 PolarHBondContact O-N 2.96Å; Y356-N360 PolarHBondContact O-N 3.32Å; Y356-N360 VanDerWaalsContact O-N 3.09Å
357	A	73.3	Confident	66.6	Low	62 Å²	62	105 Å²	105	51%	0.512	60%	0.604	S	S	.	*	H	α-helix	trans	-65.4	-43.3	177.3	0	0	0	0	0	112.4	D353 V354 K359 N360 S361	D353-A357 WeakPolarHBondContact O-CB 3.44Å; D353-A357 PolarHBondContact O-N 3.4Å; V354-A357 PolarHBondContact O-N 2.74Å; A357-K359 VanDerWaalsContact C-N 3.34Å; A357-K359 PolarHBondContact O-N 2.93Å; A357-N360 PolarHBondContact O-N 3.4Å; A357-S361 PolarHBondContact O-N 3.33Å; A357-S361 VanDerWaalsContact O-N 3.1Å
358	C	70	Confident	65.6	Low	76 Å²	76	107.3 Å²	107.3	51%	0.514	64%	0.644	S	S	.	*	H	α-helix	trans	-61.4	-42.2	174.8	-72.4	0	0	0	0	111.8	V354 N360 S361 E362	V354-C358 PolarHBondContact O-N 3.32Å; V354-C358 PolarHBondContact O-SG 3.25Å; C358-N360 VanDerWaalsContact C-N 3.32Å; C358-N360 PolarHBondContact O-N 2.98Å; C358-S361 PolarHBondContact O-N 3.47Å; C358-E362 PolarHBondContact O-N 3.23Å
359	K	72.3	Confident	65.3	Low	153 Å²	153	109 Å²	109	67%	0.665	65%	0.651	S	S	*	*	H	α-helix	trans	-64.9	-34	178.9	-167.6	175.6	-177.6	-179.4	0	113	A355 Y356 A357	A355-K359 WeakPolarHBondContact O-CB 3.38Å; A355-K359 PolarHBondContact O-N 3.11Å; A355-K359 VanDerWaalsContact O-N 3.11Å; Y356-K359 PolarHBondContact O-N 2.96Å; A357-K359 VanDerWaalsContact C-N 3.34Å; A357-K359 PolarHBondContact O-N 2.93Å
360	N	63.9	Low	65	Low	115 Å²	115	111.4 Å²	111.4	62%	0.615	66%	0.662	S	S	*	*	H	α-helix	trans	-77.4	-24.6	176.2	-73.4	-6.9	0	0	0	112.9	Y356 A357 C358 T364	Y356-N360 PolarHBondContact O-N 3.32Å; Y356-N360 VanDerWaalsContact O-N 3.09Å; A357-N360 PolarHBondContact O-N 3.4Å; C358-N360 VanDerWaalsContact C-N 3.32Å; C358-N360 PolarHBondContact O-N 2.98Å; N360-T364 PolarHBondContact O-OG1 3.22Å; N360-T364 VanDerWaalsContact O-OG1 3.13Å
361	S	60	Low	64.2	Low	80 Å²	80	111.7 Å²	111.7	56%	0.559	67%	0.669	S	S	*	*	H	α-helix	trans	-77.2	-26	176.1	-171.4	0	0	0	0	113.4	A357 C358	A357-S361 PolarHBondContact O-N 3.33Å; A357-S361 VanDerWaalsContact O-N 3.1Å; C358-S361 PolarHBondContact O-N 3.47Å
362	E	56.9	Low	63.6	Low	164 Å²	164	114.7 Å²	114.7	77%	0.766	68%	0.678	S	S	*	*	H	α-helix	trans	-79.1	-20	175	-74.9	-179.3	160.1	0	0	112.8	C358 T364	C358-E362 PolarHBondContact O-N 3.23Å; E362-T364 VanDerWaalsContact C-N 3.35Å; E362-T364 PolarHBondContact O-N 2.86Å
363	G	55	Low	62.8	Low	69 Å²	69	113.4 Å²	113.4	71%	0.711	68%	0.684	S	S	*	*	T	Hydrogen-bonded Turn	trans	-78.6	-10.7	179.2	0	0	0	0	0	115.3
364	T	54.7	Low	61.8	Low	110 Å²	110	114.6 Å²	114.6	68%	0.675	70%	0.695	S	S	*	*	T	Hydrogen-bonded Turn	trans	-103.4	0.2	-171.7	-7.3	0	0	0	0	114.7	N360 E362	N360-T364 PolarHBondContact O-OG1 3.22Å; N360-T364 VanDerWaalsContact O-OG1 3.13Å; E362-T364 VanDerWaalsContact C-N 3.35Å; E362-T364 PolarHBondContact O-N 2.86Å
365	N	48.9	Very low	60.5	Low	131 Å²	131	117.1 Å²	117.1	70%	0.701	71%	0.71	S	S	*	*			trans	-108.4	42.7	-176.5	-77.6	-10.1	0	0	0	113.8	P367	N365-P367 WeakPolarHBondContact O-CD 3.32Å
366	N	50.6	Low	59.5	Low	158 Å²	158	121.5 Å²	121.5	85%	0.845	73%	0.728	S	S	*	*			trans	-103.6	99.6	160.5	-92.2	-6.1	0	0	0	109
367	P	51.1	Low	58.4	Low	124 Å²	124	118.2 Å²	118.2	81%	0.805	74%	0.735	S	S	*	*			trans	-71.1	130.1	165.9	21.3	-14.5	0	0	0	109	N365	N365-P367 WeakPolarHBondContact O-CD 3.32Å
368	A	44.8	Very low	57.1	Low	176 Å²	176	123.3 Å²	123.3	100%	1.455	76%	0.756	S	S	*	*			trans	-68.5	0	171.7	0	0	0	0	0	112.3

Retrieved 368 of 368 residues in 171.3 ms (Link to these results)

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