A0A093H6B3_STRCA Loading...

Zinc transporter ZIP9

Transports zinc ions across cell and organelle membranes into the cytoplasm and regulates intracellular zinc homeostasis. Participates in the zinc ions efflux out of the secretory compartments. Also functions as membrane androgen receptor that mediates, through a G protein, the non-classical androgen signaling pathway, characterized by the activation of MAPK3/MAPK1 (Erk1/2) and transcription factors CREB1 or ATF1. Moreover, has dual functions as membrane-bound androgen receptor and as an androgen-dependent zinc transporter both of which are mediated through an inhibitory G protein (Gi) that mediates both MAP kinase and zinc signaling leading to the androgen-dependent apoptotic process.

AlphaFold DB , UniProt , Accession A0A093H6B3, Species STRCA (Struthio camelus australis), Gene n/a, Length 305 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	54.6	Low	86.5	Confident	171 Å²	171	65.7 Å²	65.7	84%	0.842	34%	0.338	S	S	*	.				0	135.6	0	-83.3	158.3	63.5	0	0	106.1	D3 L9	M1-D3 PolarHBondContact O-N 3.12Å; M1-L9 HydrophobicContact CE-CD1 3.37Å
2	D	80.5	Confident	87.3	Confident	113 Å²	113	68.5 Å²	68.5	60%	0.604	35%	0.353	S	S	*	.			trans	-60.3	138.9	174.3	-52	-36.6	0	0	0	108.7	F4 H5 S6	D2-F4 PolarHBondContact O-N 3.49Å; D2-H5 WeakPolarHBondContact O-CA 3.35Å; D2-H5 WeakPolarHBondContact O-CB 3.22Å; D2-H5 PolarHBondContact O-N 3.19Å; D2-H5 IonicContact OD2-CD2 3.94Å; D2-H5 PolarHBondContact OD2-CD2 3.49Å; D2-H5 IonicContact OD2-NE2 3.91Å; D2-S6 PolarHBondContact O-N 3.36Å; D2-S6 VanDerWaalsContact O-N 3.1Å
3	D	80.9	Confident	87.9	Confident	62 Å²	62	66.5 Å²	66.5	33%	0.332	35%	0.354	S	S	.	.	H	α-helix	trans	-52.9	-33.3	-176.7	-64.7	-31.6	0	0	0	111.8	M1 S6 I7 Y224	M1-D3 PolarHBondContact O-N 3.12Å; D3-S6 WeakPolarHBondContact O-CB 3.49Å; D3-S6 PolarHBondContact O-N 2.81Å; D3-I7 WeakPolarHBondContact O-CG2 3.34Å; D3-I7 PolarHBondContact O-N 3.31Å; D3-Y224 HydrophobicContact CB-CE2 4.21Å; D3-Y224 VanDerWaalsContact CB-OH 3.32Å; D3-Y224 WeakPolarHBondContact CB-OH 3.41Å
4	F	88.2	Confident	88.3	Confident	90 Å²	90	61.8 Å²	61.8	40%	0.395	33%	0.328	S	S	.	.	H	α-helix	trans	-61.3	-42.9	172.4	-177.4	-103.7	0	0	0	113.5	D2 I7 C8 M221 Y224 L225	D2-F4 PolarHBondContact O-N 3.49Å; F4-I7 VanDerWaalsContact O-CG2 3.27Å; F4-I7 WeakPolarHBondContact O-CG2 3.4Å; F4-C8 WeakPolarHBondContact O-CB 3.38Å; F4-C8 PolarHBondContact O-N 3.5Å; F4-C8 PolarHBondContact O-SG 3.19Å; F4-M221 HydrophobicContact CD2-SD 4.3Å; F4-M221 HydrophobicContact CE2-CE 4.46Å; F4-M221 HydrophobicContact CE2-SD 3.68Å; F4-Y224 HydrophobicContact CB-CE1 4.23Å; F4-Y224 HydrophobicContact CD2-CD1 4.42Å; F4-Y224 AromaticContact CD2-CE1 3.93Å; F4-Y224 HydrophobicContact CD2-CE1 3.93Å; F4-Y224 PolarHBondContact N-OH 3.42Å; F4-L225 HydrophobicContact CD2-CD2 4.41Å; F4-L225 HydrophobicContact CE2-CD2 4.2Å
5	H	90.6	Very high	88.8	Confident	103 Å²	103	60.3 Å²	60.3	48%	0.477	32%	0.32	S	S	.	.	H	α-helix	trans	-67.2	-38	175.3	-78.5	-62.6	0	0	0	111.7	D2 C8 L9	D2-H5 WeakPolarHBondContact O-CA 3.35Å; D2-H5 WeakPolarHBondContact O-CB 3.22Å; D2-H5 PolarHBondContact O-N 3.19Å; D2-H5 IonicContact OD2-CD2 3.94Å; D2-H5 PolarHBondContact OD2-CD2 3.49Å; D2-H5 IonicContact OD2-NE2 3.91Å; H5-C8 PolarHBondContact O-N 3.47Å; H5-L9 WeakPolarHBondContact O-CG 3.42Å; H5-L9 PolarHBondContact O-N 2.99Å; H5-L9 VanDerWaalsContact O-N 3.07Å
6	S	90	Very high	89.2	Confident	16 Å²	16	61.5 Å²	61.5	11%	0.112	33%	0.33	C	S	.	.	H	α-helix	trans	-59.7	-54.4	175.2	-175.1	0	0	0	0	111	D2 D3 C8 L9 L10 Q173	D2-S6 PolarHBondContact O-N 3.36Å; D2-S6 VanDerWaalsContact O-N 3.1Å; D3-S6 WeakPolarHBondContact O-CB 3.49Å; D3-S6 PolarHBondContact O-N 2.81Å; S6-C8 VanDerWaalsContact C-N 3.31Å; S6-C8 PolarHBondContact O-N 3.31Å; S6-L9 PolarHBondContact O-N 2.71Å; S6-L9 VanDerWaalsContact O-N 3.12Å; S6-L10 WeakPolarHBondContact O-CG 3.49Å; S6-L10 PolarHBondContact O-N 3.15Å; S6-Q173 PolarHBondContact OG-OE1 2.9Å
7	I	91.1	Very high	89.5	Confident	0 Å²	0	60.4 Å²	60.4	0%	0	33%	0.332	C	S	.	.	H	α-helix	trans	-65.2	-33.4	-178.9	-165.8	178.1	0	0	0	112.7	D3 F4 S11 A165 S220 M221 Y224	D3-I7 WeakPolarHBondContact O-CG2 3.34Å; D3-I7 PolarHBondContact O-N 3.31Å; F4-I7 VanDerWaalsContact O-CG2 3.27Å; F4-I7 WeakPolarHBondContact O-CG2 3.4Å; I7-S11 WeakPolarHBondContact O-CB 3.39Å; I7-S11 PolarHBondContact O-N 2.98Å; I7-S11 PolarHBondContact O-OG 3.42Å; I7-A165 HydrophobicContact CB-CB 4.31Å; I7-A165 HydrophobicContact CD1-CB 3.72Å; I7-A165 HydrophobicContact CG1-CB 4.16Å; I7-S220 WeakPolarHBondContact CD1-OG 3.29Å; I7-M221 HydrophobicContact CG2-CE 4.05Å; I7-M221 HydrophobicContact CG2-SD 4.46Å; I7-Y224 HydrophobicContact CD1-CD1 4.37Å; I7-Y224 HydrophobicContact CD1-CD2 4.01Å; I7-Y224 HydrophobicContact CD1-CG 3.64Å; I7-Y224 HydrophobicContact CG2-CD1 4.05Å; I7-Y224 HydrophobicContact CG2-CE1 4.27Å; I7-Y224 HydrophobicContact CG2-CG 4.2Å
8	C	94.1	Very high	89.7	Confident	43 Å²	43	57.1 Å²	57.1	29%	0.291	31%	0.313	S	S	.	.	H	α-helix	trans	-60.8	-46	172.4	-74.5	0	0	0	0	111.8	F4 H5 S6 S11 L12 M221	F4-C8 WeakPolarHBondContact O-CB 3.38Å; F4-C8 PolarHBondContact O-N 3.5Å; F4-C8 PolarHBondContact O-SG 3.19Å; H5-C8 PolarHBondContact O-N 3.47Å; S6-C8 VanDerWaalsContact C-N 3.31Å; S6-C8 PolarHBondContact O-N 3.31Å; C8-S11 PolarHBondContact O-N 3.16Å; C8-L12 WeakPolarHBondContact O-CB 3.31Å; C8-L12 PolarHBondContact O-N 3.15Å; C8-M221 HydrophobicContact CB-CE 4.43Å; C8-M221 WeakPolarHBondContact SG-CE 3.41Å
9	L	94	Very high	90	Very high	97 Å²	97	58 Å²	58	51%	0.508	31%	0.312	S	S	.	.	H	α-helix	trans	-67	-44.4	179.4	-75.2	167.7	0	0	0	111.8	M1 H5 S6 S11 L12 A13	M1-L9 HydrophobicContact CE-CD1 3.37Å; H5-L9 WeakPolarHBondContact O-CG 3.42Å; H5-L9 PolarHBondContact O-N 2.99Å; H5-L9 VanDerWaalsContact O-N 3.07Å; S6-L9 PolarHBondContact O-N 2.71Å; S6-L9 VanDerWaalsContact O-N 3.12Å; L9-S11 VanDerWaalsContact C-N 3.34Å; L9-S11 PolarHBondContact O-N 3.45Å; L9-L12 PolarHBondContact O-N 3.4Å; L9-A13 WeakPolarHBondContact O-CB 3.29Å; L9-A13 PolarHBondContact O-N 3.44Å
10	L	93.1	Very high	90.2	Very high	19 Å²	19	59.4 Å²	59.4	10%	0.099	32%	0.323	C	S	.	.	H	α-helix	trans	-62.8	-42.1	176.1	-65.2	-178.4	0	0	0	111.3	S6 L12 A13 M14 Q173 L174 F177	S6-L10 WeakPolarHBondContact O-CG 3.49Å; S6-L10 PolarHBondContact O-N 3.15Å; L10-L12 PolarHBondContact O-N 2.89Å; L10-A13 PolarHBondContact O-N 3Å; L10-M14 VanDerWaalsContact O-CB 3.29Å; L10-M14 WeakPolarHBondContact O-CB 3.32Å; L10-M14 PolarHBondContact O-N 3.18Å; L10-Q173 HydrophobicContact CD1-CG 3.84Å; L10-L174 HydrophobicContact CD1-CD2 4.4Å; L10-L174 HydrophobicContact CD2-CD2 4.17Å; L10-F177 HydrophobicContact CB-CD2 3.84Å; L10-F177 HydrophobicContact CB-CE2 3.94Å; L10-F177 HydrophobicContact CB-CG 4.47Å; L10-F177 HydrophobicContact CD1-CB 4.29Å; L10-F177 HydrophobicContact CD1-CD2 4.42Å; L10-F177 HydrophobicContact CD1-CG 4.31Å; L10-F177 HydrophobicContact CD2-CD1 3.8Å; L10-F177 HydrophobicContact CD2-CD2 3.94Å; L10-F177 HydrophobicContact CD2-CE1 3.87Å; L10-F177 HydrophobicContact CD2-CE2 4.01Å; L10-F177 HydrophobicContact CD2-CG 3.82Å; L10-F177 HydrophobicContact CD2-CZ 3.98Å; L10-F177 HydrophobicContact CG-CD2 4.28Å; L10-F177 HydrophobicContact CG-CG 4.42Å; L10-F177 VanDerWaalsContact O-CE2 3.31Å; L10-F177 WeakPolarHBondContact O-CE2 3.33Å
11	S	94.8	Very high	90.3	Very high	9 Å²	9	57.2 Å²	57.2	6%	0.063	31%	0.313	C	S	.	.	H	α-helix	trans	-61.6	-42.1	175.9	-66.3	0	0	0	0	112.1	I7 C8 L9 M14 L15 P217	I7-S11 WeakPolarHBondContact O-CB 3.39Å; I7-S11 PolarHBondContact O-N 2.98Å; I7-S11 PolarHBondContact O-OG 3.42Å; C8-S11 PolarHBondContact O-N 3.16Å; L9-S11 VanDerWaalsContact C-N 3.34Å; L9-S11 PolarHBondContact O-N 3.45Å; S11-M14 PolarHBondContact O-N 3.48Å; S11-L15 WeakPolarHBondContact O-CB 3.42Å; S11-L15 PolarHBondContact O-N 2.9Å; S11-P217 WeakPolarHBondContact O-CG 3.48Å
12	L	95.7	Very high	92.1	Very high	99 Å²	99	49.1 Å²	49.1	52%	0.518	27%	0.273	S	S	.	.	H	α-helix	trans	-67.3	-45.7	176.4	-179.6	63.5	0	0	0	111.7	C8 L9 L10 M14 L15 V16	C8-L12 WeakPolarHBondContact O-CB 3.31Å; C8-L12 PolarHBondContact O-N 3.15Å; L9-L12 PolarHBondContact O-N 3.4Å; L10-L12 PolarHBondContact O-N 2.89Å; L12-M14 VanDerWaalsContact C-N 3.28Å; L12-M14 PolarHBondContact O-N 3.43Å; L12-L15 WeakPolarHBondContact O-CB 3.19Å; L12-L15 PolarHBondContact O-N 2.81Å; L12-V16 HydrophobicContact CD1-CG2 4.29Å; L12-V16 WeakPolarHBondContact O-CG2 3.24Å; L12-V16 PolarHBondContact O-N 3.22Å
13	A	94.6	Very high	92.8	Very high	43 Å²	43	46 Å²	46	36%	0.355	26%	0.256	S	S	.	.	H	α-helix	trans	-58.8	-43.2	176.6	0	0	0	0	0	110.8	L9 L10 V16 A17 F177	L9-A13 WeakPolarHBondContact O-CB 3.29Å; L9-A13 PolarHBondContact O-N 3.44Å; L10-A13 PolarHBondContact O-N 3Å; A13-V16 PolarHBondContact O-N 2.92Å; A13-A17 VanDerWaalsContact O-CB 3.24Å; A13-A17 WeakPolarHBondContact O-CB 3.29Å; A13-A17 PolarHBondContact O-N 2.84Å; A13-F177 HydrophobicContact CB-CZ 4.01Å
14	M	94.1	Very high	93.3	Very high	0 Å²	0	47.5 Å²	47.5	0%	0	26%	0.263	C	S	.	.	H	α-helix	trans	-61.3	-46.4	176.8	-166	-170.6	-55.6	0	0	112.6	L10 S11 L12 C18 L161 F177 I180 M181 K184 A216	L10-M14 VanDerWaalsContact O-CB 3.29Å; L10-M14 WeakPolarHBondContact O-CB 3.32Å; L10-M14 PolarHBondContact O-N 3.18Å; S11-M14 PolarHBondContact O-N 3.48Å; L12-M14 VanDerWaalsContact C-N 3.28Å; L12-M14 PolarHBondContact O-N 3.43Å; M14-C18 WeakPolarHBondContact O-CB 3.29Å; M14-C18 PolarHBondContact O-N 2.79Å; M14-L161 HydrophobicContact CE-CD2 3.2Å; M14-F177 HydrophobicContact CB-CE2 4.14Å; M14-F177 HydrophobicContact CE-CD2 4.16Å; M14-F177 HydrophobicContact CE-CE2 4.36Å; M14-I180 HydrophobicContact CE-CG2 4.09Å; M14-I180 HydrophobicContact SD-CG2 4.11Å; M14-M181 HydrophobicContact CB-CE 4.35Å; M14-M181 HydrophobicContact CB-SD 4.15Å; M14-M181 HydrophobicContact CG-CE 3.61Å; M14-M181 HydrophobicContact CG-SD 3.99Å; M14-K184 HydrophobicContact CG-CD 3.7Å; M14-K184 HydrophobicContact SD-CD 3.89Å; M14-A216 HydrophobicContact SD-CB 3.43Å; M14-A216 WeakPolarHBondContact SD-CB 3.45Å
15	L	96	Very high	93.3	Very high	40 Å²	40	43.2 Å²	43.2	21%	0.209	24%	0.244	C	C	.	.	H	α-helix	trans	-57.3	-51.9	176.8	176.7	60.6	0	0	0	111	S11 L12 Y19 A213 L214 P217	S11-L15 WeakPolarHBondContact O-CB 3.42Å; S11-L15 PolarHBondContact O-N 2.9Å; L12-L15 WeakPolarHBondContact O-CB 3.19Å; L12-L15 PolarHBondContact O-N 2.81Å; L15-Y19 VanDerWaalsContact O-CB 3.26Å; L15-Y19 WeakPolarHBondContact O-CB 3.21Å; L15-Y19 PolarHBondContact O-N 2.85Å; L15-A213 HydrophobicContact CD1-CB 3.79Å; L15-A213 WeakPolarHBondContact CD1-O 3.24Å; L15-L214 HydrophobicContact CD1-CD2 3.69Å; L15-L214 HydrophobicContact CD1-CG 3.92Å; L15-L214 HydrophobicContact CD2-CD2 3.91Å; L15-L214 HydrophobicContact CG-CD2 4.47Å; L15-P217 HydrophobicContact CB-CG 3.94Å
16	V	95.6	Very high	93.2	Very high	79 Å²	79	38.6 Å²	38.6	48%	0.479	22%	0.223	S	C	.	.	H	α-helix	trans	-65.3	-50.1	-176.4	173.9	0	0	0	0	110.8	L12 A13 C18 Y19 V20	L12-V16 HydrophobicContact CD1-CG2 4.29Å; L12-V16 WeakPolarHBondContact O-CG2 3.24Å; L12-V16 PolarHBondContact O-N 3.22Å; A13-V16 PolarHBondContact O-N 2.92Å; V16-C18 PolarHBondContact O-N 2.73Å; V16-Y19 PolarHBondContact O-N 3.5Å; V16-V20 HydrophobicContact CG1-CG2 4.21Å; V16-V20 WeakPolarHBondContact O-CB 3.5Å; V16-V20 VanDerWaalsContact O-CG2 3.25Å; V16-V20 WeakPolarHBondContact O-CG2 3.38Å; V16-V20 PolarHBondContact O-N 2.87Å
17	A	93.3	Very high	93.1	Very high	43 Å²	43	41.5 Å²	41.5	36%	0.355	25%	0.248	S	C	.	.	H	α-helix	trans	-61.4	-46	-178.6	0	0	0	0	0	111.7	A13 Y19 V20 A21 M181	A13-A17 VanDerWaalsContact O-CB 3.24Å; A13-A17 WeakPolarHBondContact O-CB 3.29Å; A13-A17 PolarHBondContact O-N 2.84Å; A17-Y19 PolarHBondContact O-N 3.06Å; A17-V20 PolarHBondContact O-N 3.31Å; A17-A21 VanDerWaalsContact O-CB 3.31Å; A17-A21 WeakPolarHBondContact O-CB 3.3Å; A17-A21 PolarHBondContact O-N 3.4Å; A17-M181 HydrophobicContact CB-CE 4.27Å; A17-M181 HydrophobicContact CB-SD 3.82Å
18	C	94.4	Very high	93	Very high	0 Å²	0	44.6 Å²	44.6	0%	0	27%	0.266	C	S	.	.	H	α-helix	trans	-61	-45.8	176.9	-179.4	0	0	0	0	111.9	M14 V16 G22 K184 A188 F212 A213	M14-C18 WeakPolarHBondContact O-CB 3.29Å; M14-C18 PolarHBondContact O-N 2.79Å; V16-C18 PolarHBondContact O-N 2.73Å; C18-G22 PolarHBondContact O-N 2.91Å; C18-K184 HydrophobicContact CB-CD 4.05Å; C18-K184 HydrophobicContact CB-CG 4Å; C18-A188 WeakPolarHBondContact O-CB 3.04Å; C18-F212 WeakPolarHBondContact SG-CE1 2.95Å; C18-A213 HydrophobicContact CB-CB 4.15Å
19	Y	95.3	Very high	92.5	Very high	75 Å²	75	48.8 Å²	48.8	29%	0.294	29%	0.286	S	S	.	.	H	α-helix	trans	-66.2	-45.6	-179.4	-170.3	-96.4	0	0	0	111.3	L15 V16 A17 A21 G22 I23 L209 L210	L15-Y19 VanDerWaalsContact O-CB 3.26Å; L15-Y19 WeakPolarHBondContact O-CB 3.21Å; L15-Y19 PolarHBondContact O-N 2.85Å; V16-Y19 PolarHBondContact O-N 3.5Å; A17-Y19 PolarHBondContact O-N 3.06Å; Y19-A21 PolarHBondContact O-N 3.33Å; Y19-G22 PolarHBondContact O-N 3.2Å; Y19-I23 HydrophobicContact CD1-CG1 3.99Å; Y19-I23 HydrophobicContact CE1-CD1 4.02Å; Y19-I23 HydrophobicContact CE1-CG1 3.67Å; Y19-I23 WeakPolarHBondContact O-CG1 3.47Å; Y19-I23 PolarHBondContact O-N 2.78Å; Y19-L209 HydrophobicContact CD2-CD2 3.97Å; Y19-L209 HydrophobicContact CD2-CG 3.88Å; Y19-L209 HydrophobicContact CE2-CD2 4Å; Y19-L209 HydrophobicContact CE2-CG 4.1Å; Y19-L210 HydrophobicContact CD2-CD1 4.4Å; Y19-L210 HydrophobicContact CE2-CB 4.21Å; Y19-L210 HydrophobicContact CE2-CD1 4.34Å
20	V	94.3	Very high	92	Very high	86 Å²	86	47.1 Å²	47.1	52%	0.521	28%	0.275	S	S	.	.	H	α-helix	trans	-60.3	-47.5	177.7	170.5	0	0	0	0	110.8	V16 A17 G22 I23 I24	V16-V20 HydrophobicContact CG1-CG2 4.21Å; V16-V20 WeakPolarHBondContact O-CB 3.5Å; V16-V20 VanDerWaalsContact O-CG2 3.25Å; V16-V20 WeakPolarHBondContact O-CG2 3.38Å; V16-V20 PolarHBondContact O-N 2.87Å; A17-V20 PolarHBondContact O-N 3.31Å; V20-G22 VanDerWaalsContact C-N 3.32Å; V20-G22 PolarHBondContact O-N 2.65Å; V20-I23 PolarHBondContact O-N 3.34Å; V20-I23 VanDerWaalsContact O-N 3.1Å; V20-I24 PolarHBondContact O-N 3.22Å
21	A	92.3	Very high	91.8	Very high	14 Å²	14	49 Å²	49	12%	0.116	29%	0.289	C	S	.	.	H	α-helix	trans	-58.3	-43.2	177.4	0	0	0	0	0	112.2	A17 Y19 I23 I24 A185	A17-A21 VanDerWaalsContact O-CB 3.31Å; A17-A21 WeakPolarHBondContact O-CB 3.3Å; A17-A21 PolarHBondContact O-N 3.4Å; Y19-A21 PolarHBondContact O-N 3.33Å; A21-I23 VanDerWaalsContact C-N 3.32Å; A21-I23 PolarHBondContact O-N 3.28Å; A21-I24 WeakPolarHBondContact O-CB 3.31Å; A21-I24 PolarHBondContact O-N 2.93Å; A21-A185 HydrophobicContact CB-CB 3.68Å
22	G	92	Very high	91.2	Very high	0 Å²	0	56.8 Å²	56.8	0%	0	33%	0.325	C	S	.	.	H	α-helix	trans	-70	-22.1	177	0	0	0	0	0	114.5	C18 Y19 V20 I24 P25 V192	C18-G22 PolarHBondContact O-N 2.91Å; Y19-G22 PolarHBondContact O-N 3.2Å; V20-G22 VanDerWaalsContact C-N 3.32Å; V20-G22 PolarHBondContact O-N 2.65Å; G22-I24 VanDerWaalsContact C-N 3.31Å; G22-P25 WeakPolarHBondContact O-CD 3.27Å; G22-V192 WeakPolarHBondContact O-CB 3.08Å; G22-V192 WeakPolarHBondContact O-CG1 3.18Å; G22-V192 VanDerWaalsContact O-CG2 3.32Å; G22-V192 WeakPolarHBondContact O-CG2 3.34Å
23	I	94.1	Very high	90.6	Very high	48 Å²	48	59.6 Å²	59.6	25%	0.246	34%	0.335	C	S	.	.	H	α-helix	trans	-76.1	-20.9	174.7	-70.1	-65.5	0	0	0	111.9	Y19 V20 A21 L26 A27 R206 L209	Y19-I23 HydrophobicContact CD1-CG1 3.99Å; Y19-I23 HydrophobicContact CE1-CD1 4.02Å; Y19-I23 HydrophobicContact CE1-CG1 3.67Å; Y19-I23 WeakPolarHBondContact O-CG1 3.47Å; Y19-I23 PolarHBondContact O-N 2.78Å; V20-I23 PolarHBondContact O-N 3.34Å; V20-I23 VanDerWaalsContact O-N 3.1Å; A21-I23 VanDerWaalsContact C-N 3.32Å; A21-I23 PolarHBondContact O-N 3.28Å; I23-L26 HydrophobicContact CD1-CD1 4.01Å; I23-L26 WeakPolarHBondContact O-CB 3.2Å; I23-L26 PolarHBondContact O-N 3.5Å; I23-A27 PolarHBondContact O-N 3.26Å; I23-R206 HydrophobicContact CD1-CG 4.27Å; I23-L209 HydrophobicContact CD1-CD2 3.84Å; I23-L209 HydrophobicContact CG1-CD2 3.94Å
24	I	92	Very high	90.3	Very high	93 Å²	93	65.3 Å²	65.3	48%	0.477	35%	0.348	S	S	.	.	H	α-helix	trans	-54.9	-52.3	-176.8	-63	170.4	0	0	0	112.4	V20 A21 G22 L26 A27	V20-I24 PolarHBondContact O-N 3.22Å; A21-I24 WeakPolarHBondContact O-CB 3.31Å; A21-I24 PolarHBondContact O-N 2.93Å; G22-I24 VanDerWaalsContact C-N 3.31Å; I24-L26 VanDerWaalsContact C-N 3.27Å; I24-L26 PolarHBondContact O-N 2.89Å; I24-A27 PolarHBondContact O-N 2.94Å
25	P	88.1	Confident	89.9	Confident	1 Å²	1	66.6 Å²	66.6	1%	0.006	35%	0.354	C	S	.	.	H	α-helix	trans	-61	-34.9	177.1	-18.8	28.3	0	0	0	113.2	G22 A27 V28 F30 F189 V192 M196	G22-P25 WeakPolarHBondContact O-CD 3.27Å; P25-A27 VanDerWaalsContact C-N 3.33Å; P25-A27 PolarHBondContact O-N 3.49Å; P25-V28 PolarHBondContact O-N 3.44Å; P25-F30 WeakPolarHBondContact O-CE2 3.33Å; P25-F189 HydrophobicContact CB-CE2 4.49Å; P25-F189 HydrophobicContact CG-CD2 3.46Å; P25-F189 VanDerWaalsContact CG-CD2 3.46Å; P25-F189 HydrophobicContact CG-CE2 3.65Å; P25-F189 HydrophobicContact CG-CG 3.97Å; P25-F189 HydrophobicContact CG-CZ 4.29Å; P25-V192 HydrophobicContact CB-CG1 3.95Å; P25-V192 HydrophobicContact CG-CB 4.25Å; P25-V192 HydrophobicContact CG-CG1 4.11Å; P25-M196 VanDerWaalsContact C-SD 3.57Å; P25-M196 HydrophobicContact CB-SD 3.91Å; P25-M196 WeakPolarHBondContact O-CE 3.42Å
26	L	88.7	Confident	89.4	Confident	6 Å²	6	66.9 Å²	66.9	3%	0.031	35%	0.354	C	S	.	.	H	α-helix	trans	-69.7	-29.2	179.1	-80.2	163.5	0	0	0	113	I23 I24 V28 V192 M196 R202 I205 R206	I23-L26 HydrophobicContact CD1-CD1 4.01Å; I23-L26 WeakPolarHBondContact O-CB 3.2Å; I23-L26 PolarHBondContact O-N 3.5Å; I24-L26 VanDerWaalsContact C-N 3.27Å; I24-L26 PolarHBondContact O-N 2.89Å; L26-V28 VanDerWaalsContact C-N 3.27Å; L26-V28 PolarHBondContact O-N 3.38Å; L26-V192 HydrophobicContact CD1-CG1 3.82Å; L26-V192 HydrophobicContact CD2-CG1 4.4Å; L26-V192 HydrophobicContact CG-CG1 3.54Å; L26-M196 HydrophobicContact CD2-CG 3.99Å; L26-M196 HydrophobicContact CD2-SD 3.91Å; L26-M196 HydrophobicContact CG-SD 4.06Å; L26-R202 HydrophobicContact CD2-CB 4.45Å; L26-R202 HydrophobicContact CD2-CG 4.19Å; L26-R202 PolarHBondContact O-NH1 3.48Å; L26-I205 HydrophobicContact CD1-CB 4.41Å; L26-I205 HydrophobicContact CD1-CG2 3.82Å; L26-I205 HydrophobicContact CD2-CB 4.3Å; L26-I205 HydrophobicContact CD2-CD1 4.1Å; L26-I205 HydrophobicContact CD2-CG2 4.11Å; L26-I205 HydrophobicContact CG-CG2 4.27Å; L26-R206 HydrophobicContact CD1-CG 4.3Å
27	A	88.4	Confident	89	Confident	76 Å²	76	65.4 Å²	65.4	63%	0.628	34%	0.343	S	S	*	.	H	α-helix	trans	-74.6	-19.6	-179.4	0	0	0	0	0	112.7	I23 I24 P25	I23-A27 PolarHBondContact O-N 3.26Å; I24-A27 PolarHBondContact O-N 2.94Å; P25-A27 VanDerWaalsContact C-N 3.33Å; P25-A27 PolarHBondContact O-N 3.49Å
28	V	88	Confident	88.9	Confident	65 Å²	65	64.3 Å²	64.3	39%	0.394	33%	0.332	S	S	.	.	S	Bend	trans	-98.6	138.2	-177.8	-176.4	0	0	0	0	110.5	P25 L26 F30	P25-V28 PolarHBondContact O-N 3.44Å; L26-V28 VanDerWaalsContact C-N 3.27Å; L26-V28 PolarHBondContact O-N 3.38Å; V28-F30 HydrophobicContact CB-CD2 4.34Å; V28-F30 HydrophobicContact CB-CE1 4.26Å; V28-F30 HydrophobicContact CB-CE2 3.65Å; V28-F30 HydrophobicContact CB-CZ 3.6Å; V28-F30 HydrophobicContact CG1-CD1 4.11Å; V28-F30 HydrophobicContact CG1-CD2 4.33Å; V28-F30 HydrophobicContact CG1-CE1 3.61Å; V28-F30 HydrophobicContact CG1-CE2 3.87Å; V28-F30 HydrophobicContact CG1-CG 4.46Å; V28-F30 HydrophobicContact CG1-CZ 3.48Å; V28-F30 VanDerWaalsContact CG1-CZ 3.48Å; V28-F30 HydrophobicContact CG2-CZ 4.36Å
29	N	84.7	Confident	88.5	Confident	132 Å²	132	64.4 Å²	64.4	71%	0.706	33%	0.332	S	S	*	.			trans	-91	111.2	174.1	-68.1	-40	0	0	0	109.7	R202	N29-R202 PolarHBondContact OD1-NH2 3.27Å
30	F	83.6	Confident	88.2	Confident	62 Å²	62	60.8 Å²	60.8	27%	0.272	32%	0.318	S	S	.	.			trans	-101.3	144.4	178.5	-62.1	-73.5	0	0	0	111.4	P25 V28 R34 L35 V38 M196	P25-F30 WeakPolarHBondContact O-CE2 3.33Å; V28-F30 HydrophobicContact CB-CD2 4.34Å; V28-F30 HydrophobicContact CB-CE1 4.26Å; V28-F30 HydrophobicContact CB-CE2 3.65Å; V28-F30 HydrophobicContact CB-CZ 3.6Å; V28-F30 HydrophobicContact CG1-CD1 4.11Å; V28-F30 HydrophobicContact CG1-CD2 4.33Å; V28-F30 HydrophobicContact CG1-CE1 3.61Å; V28-F30 HydrophobicContact CG1-CE2 3.87Å; V28-F30 HydrophobicContact CG1-CG 4.46Å; V28-F30 HydrophobicContact CG1-CZ 3.48Å; V28-F30 VanDerWaalsContact CG1-CZ 3.48Å; V28-F30 HydrophobicContact CG2-CZ 4.36Å; F30-R34 HydrophobicContact CB-CB 4.29Å; F30-R34 HydrophobicContact CD1-CB 4.1Å; F30-L35 HydrophobicContact CB-CB 4Å; F30-L35 HydrophobicContact CD2-CD1 4.38Å; F30-V38 HydrophobicContact CD1-CG2 4.17Å; F30-V38 HydrophobicContact CE1-CG2 3.79Å; F30-V38 HydrophobicContact CZ-CG1 4.48Å; F30-V38 HydrophobicContact CZ-CG2 4.11Å; F30-M196 HydrophobicContact CD2-CE 4.05Å
31	S	87.7	Confident	88	Confident	58 Å²	58	58.4 Å²	58.4	41%	0.406	30%	0.303	S	S	.	.			trans	-72.7	163.3	160.4	61.4	0	0	0	0	110	E33 R34 L35	S31-E33 VanDerWaalsContact C-N 3.31Å; S31-E33 PolarHBondContact O-N 3.04Å; S31-R34 PolarHBondContact O-N 2.99Å; S31-R34 VanDerWaalsContact O-N 3.15Å; S31-R34 WeakPolarHBondContact OG-CG 3.32Å; S31-R34 PolarHBondContact OG-N 3.42Å; S31-L35 WeakPolarHBondContact O-CB 3.46Å; S31-L35 PolarHBondContact O-N 3.07Å
32	E	82.4	Confident	87.9	Confident	172 Å²	172	57.8 Å²	57.8	80%	0.804	30%	0.298	S	S	*	.	H	α-helix	trans	-56.3	-42.8	180	-66.5	-173	171.3	0	0	112.9	L35 K36	E32-L35 PolarHBondContact O-N 2.87Å; E32-K36 WeakPolarHBondContact O-CB 3.25Å; E32-K36 PolarHBondContact O-N 3.1Å
33	E	83.6	Confident	87.6	Confident	158 Å²	158	58 Å²	58	74%	0.738	30%	0.299	S	S	*	.	H	α-helix	trans	-62.9	-43.3	177	-63.9	-177.3	165.4	0	0	112.5	S31 K36 L37	S31-E33 VanDerWaalsContact C-N 3.31Å; S31-E33 PolarHBondContact O-N 3.04Å; E33-K36 PolarHBondContact O-N 3.05Å; E33-L37 PolarHBondContact O-N 3.12Å; E33-L37 VanDerWaalsContact O-N 3.12Å
34	R	86.9	Confident	87.5	Confident	163 Å²	163	55.7 Å²	55.7	62%	0.615	29%	0.287	S	S	*	.	H	α-helix	trans	-69.4	-38.9	178	-69.9	177.8	-177.1	-177	1.4	111.1	F30 S31 K36 L37 V38	F30-R34 HydrophobicContact CB-CB 4.29Å; F30-R34 HydrophobicContact CD1-CB 4.1Å; S31-R34 PolarHBondContact O-N 2.99Å; S31-R34 VanDerWaalsContact O-N 3.15Å; S31-R34 WeakPolarHBondContact OG-CG 3.32Å; S31-R34 PolarHBondContact OG-N 3.42Å; R34-K36 VanDerWaalsContact C-N 3.3Å; R34-K36 PolarHBondContact O-N 3.46Å; R34-L37 PolarHBondContact O-N 3.17Å; R34-V38 WeakPolarHBondContact O-CB 3.38Å; R34-V38 VanDerWaalsContact O-CG2 3.22Å; R34-V38 WeakPolarHBondContact O-CG2 3.37Å; R34-V38 PolarHBondContact O-N 3.39Å
35	L	85.9	Confident	87.4	Confident	27 Å²	27	51.9 Å²	51.9	14%	0.141	27%	0.268	C	S	.	.	H	α-helix	trans	-63.3	-40.4	176.7	-175.7	59.4	0	0	0	110.6	F30 S31 E32 V38 T39 M196 H197	F30-L35 HydrophobicContact CB-CB 4Å; F30-L35 HydrophobicContact CD2-CD1 4.38Å; S31-L35 WeakPolarHBondContact O-CB 3.46Å; S31-L35 PolarHBondContact O-N 3.07Å; E32-L35 PolarHBondContact O-N 2.87Å; L35-V38 PolarHBondContact O-N 3Å; L35-T39 WeakPolarHBondContact O-CB 3.38Å; L35-T39 PolarHBondContact O-N 3.26Å; L35-T39 PolarHBondContact O-OG1 3.09Å; L35-M196 HydrophobicContact CD1-CB 3.87Å; L35-M196 HydrophobicContact CD1-CE 4.24Å; L35-M196 HydrophobicContact CD2-CB 4.46Å; L35-H197 HydrophobicContact CD2-CB 4.35Å; L35-H197 HydrophobicContact CG-CB 4.1Å
36	K	85.8	Confident	87.3	Confident	46 Å²	46	51.9 Å²	51.9	20%	0.2	27%	0.267	C	S	.	.	H	α-helix	trans	-58.9	-50.5	173.1	-165.7	179.6	-171.7	-158.5	0	111.3	E32 E33 R34 V38 T39 V40 E285	E32-K36 WeakPolarHBondContact O-CB 3.25Å; E32-K36 PolarHBondContact O-N 3.1Å; E33-K36 PolarHBondContact O-N 3.05Å; R34-K36 VanDerWaalsContact C-N 3.3Å; R34-K36 PolarHBondContact O-N 3.46Å; K36-V38 VanDerWaalsContact C-N 3.34Å; K36-V38 PolarHBondContact O-N 3.11Å; K36-T39 PolarHBondContact O-N 3.31Å; K36-V40 WeakPolarHBondContact O-CG2 3.39Å; K36-V40 PolarHBondContact O-N 3Å; K36-E285 WeakPolarHBondContact CD-OE1 3.24Å; K36-E285 WeakPolarHBondContact CE-OE1 3.11Å; K36-E285 IonicContact NZ-OE1 3.38Å; K36-E285 PolarHBondContact NZ-OE1 2.93Å
37	L	88.4	Confident	87.3	Confident	48 Å²	48	53.1 Å²	53.1	25%	0.251	28%	0.277	S	S	.	.	H	α-helix	trans	-60.5	-40.7	177.3	-71.2	170.9	0	0	0	113	E33 R34 T39 V40 L41 L284 E285 A288	E33-L37 PolarHBondContact O-N 3.12Å; E33-L37 VanDerWaalsContact O-N 3.12Å; R34-L37 PolarHBondContact O-N 3.17Å; L37-T39 VanDerWaalsContact C-N 3.33Å; L37-V40 PolarHBondContact O-N 3.08Å; L37-L41 VanDerWaalsContact O-CB 3.29Å; L37-L41 WeakPolarHBondContact O-CB 3.3Å; L37-L41 PolarHBondContact O-N 3.49Å; L37-L284 HydrophobicContact CD1-CD2 3.65Å; L37-L284 HydrophobicContact CD1-CG 4.23Å; L37-L284 HydrophobicContact CD2-CB 4.39Å; L37-L284 HydrophobicContact CD2-CD2 3.93Å; L37-L284 HydrophobicContact CD2-CG 3.75Å; L37-L284 HydrophobicContact CG-CD2 4.39Å; L37-E285 HydrophobicContact CD2-CG 4.03Å; L37-A288 HydrophobicContact CD2-CB 4.23Å
38	V	89.5	Confident	87.4	Confident	21 Å²	21	49.8 Å²	49.8	13%	0.127	25%	0.25	C	C	.	.	H	α-helix	trans	-66.3	-36	177.7	168.9	0	0	0	0	111.3	F30 R34 L35 K36 G42 F189 S193	F30-V38 HydrophobicContact CD1-CG2 4.17Å; F30-V38 HydrophobicContact CE1-CG2 3.79Å; F30-V38 HydrophobicContact CZ-CG1 4.48Å; F30-V38 HydrophobicContact CZ-CG2 4.11Å; R34-V38 WeakPolarHBondContact O-CB 3.38Å; R34-V38 VanDerWaalsContact O-CG2 3.22Å; R34-V38 WeakPolarHBondContact O-CG2 3.37Å; R34-V38 PolarHBondContact O-N 3.39Å; L35-V38 PolarHBondContact O-N 3Å; K36-V38 VanDerWaalsContact C-N 3.34Å; K36-V38 PolarHBondContact O-N 3.11Å; V38-G42 PolarHBondContact O-N 3.39Å; V38-F189 HydrophobicContact CG1-CE1 4.04Å; V38-F189 HydrophobicContact CG1-CZ 3.86Å; V38-S193 WeakPolarHBondContact CG1-OG 3.35Å
39	T	86.9	Confident	87.4	Confident	1 Å²	1	46.7 Å²	46.7	1%	0.006	23%	0.231	C	C	.	.	H	α-helix	trans	-69.7	-40.5	173.3	-58.1	0	0	0	0	112.1	L35 K36 L37 L41 G42 A43 S193 F194 H197 V264	L35-T39 WeakPolarHBondContact O-CB 3.38Å; L35-T39 PolarHBondContact O-N 3.26Å; L35-T39 PolarHBondContact O-OG1 3.09Å; K36-T39 PolarHBondContact O-N 3.31Å; L37-T39 VanDerWaalsContact C-N 3.33Å; T39-L41 VanDerWaalsContact C-N 3.35Å; T39-G42 CarbonylContact O-C 3.56Å; T39-G42 WeakPolarHBondContact O-CA 3.26Å; T39-G42 PolarHBondContact O-N 2.98Å; T39-A43 PolarHBondContact O-N 3.46Å; T39-S193 PolarHBondContact OG1-O 3.29Å; T39-F194 HydrophobicContact CG2-CB 4.37Å; T39-F194 HydrophobicContact CG2-CD2 4.38Å; T39-H197 HydrophobicContact CG2-CB 4.14Å; T39-H197 WeakPolarHBondContact OG1-CB 3.34Å; T39-V264 HydrophobicContact CG2-CG2 3.68Å
40	V	88.9	Confident	87.6	Confident	0 Å²	0	40.4 Å²	40.4	0%	0	20%	0.197	C	C	.	.	H	α-helix	trans	-62.3	-45.1	174.6	-174	0	0	0	0	110.5	K36 L37 G42 A43 G44 V264 E285 A288 L289	K36-V40 WeakPolarHBondContact O-CG2 3.39Å; K36-V40 PolarHBondContact O-N 3Å; L37-V40 PolarHBondContact O-N 3.08Å; V40-G42 VanDerWaalsContact C-N 3.3Å; V40-G42 PolarHBondContact O-N 2.9Å; V40-A43 WeakPolarHBondContact O-CB 3.39Å; V40-A43 PolarHBondContact O-N 3.16Å; V40-G44 PolarHBondContact O-N 3.2Å; V40-V264 HydrophobicContact CB-CG1 4Å; V40-V264 HydrophobicContact CG1-CG1 4.27Å; V40-V264 HydrophobicContact CG2-CG1 3.15Å; V40-E285 HydrophobicContact CG1-CB 4.23Å; V40-E285 WeakPolarHBondContact CG1-O 3.44Å; V40-E285 HydrophobicContact CG2-CB 4.15Å; V40-E285 HydrophobicContact CG2-CG 3.98Å; V40-A288 HydrophobicContact CB-CB 4.44Å; V40-A288 HydrophobicContact CG1-CB 4.4Å; V40-L289 HydrophobicContact CG1-CB 3.74Å; V40-L289 HydrophobicContact CG1-CD1 4.25Å
41	L	90.6	Very high	88	Confident	36 Å²	36	42 Å²	42	19%	0.188	21%	0.208	C	C	.	.	H	α-helix	trans	-58	-45.7	172.8	-179.1	75.2	0	0	0	110.4	L37 T39 A43 G44 L45 A288 L291 I295	L37-L41 VanDerWaalsContact O-CB 3.29Å; L37-L41 WeakPolarHBondContact O-CB 3.3Å; L37-L41 PolarHBondContact O-N 3.49Å; T39-L41 VanDerWaalsContact C-N 3.35Å; L41-A43 PolarHBondContact O-N 3.14Å; L41-G44 CarbonylContact O-C 3.56Å; L41-G44 PolarHBondContact O-N 3.5Å; L41-L45 HydrophobicContact CG-CD1 4.4Å; L41-L45 WeakPolarHBondContact O-CG 3.4Å; L41-L45 PolarHBondContact O-N 3.35Å; L41-A288 WeakPolarHBondContact CD1-O 3.49Å; L41-L291 HydrophobicContact CD1-CB 4.23Å; L41-L291 HydrophobicContact CD1-CD2 4.19Å; L41-L291 HydrophobicContact CD1-CG 4.27Å; L41-I295 HydrophobicContact CD1-CD1 4.26Å
42	G	88.9	Confident	88.1	Confident	1 Å²	1	39.9 Å²	39.9	1%	0.01	19%	0.194	C	C	.	.	H	α-helix	trans	-55.3	-47.6	174.2	0	0	0	0	0	112.5	V38 T39 V40 G44 L45 L46	V38-G42 PolarHBondContact O-N 3.39Å; T39-G42 CarbonylContact O-C 3.56Å; T39-G42 WeakPolarHBondContact O-CA 3.26Å; T39-G42 PolarHBondContact O-N 2.98Å; V40-G42 VanDerWaalsContact C-N 3.3Å; V40-G42 PolarHBondContact O-N 2.9Å; G42-G44 VanDerWaalsContact C-N 3.31Å; G42-G44 PolarHBondContact O-N 2.89Å; G42-L45 WeakPolarHBondContact O-CB 3.44Å; G42-L45 PolarHBondContact O-N 3.21Å; G42-L45 VanDerWaalsContact O-N 3.13Å; G42-L46 WeakPolarHBondContact O-CG 3.46Å; G42-L46 PolarHBondContact O-N 3.29Å
43	A	87.1	Confident	88.3	Confident	3 Å²	3	31.8 Å²	31.8	3%	0.025	16%	0.156	C	C	.	.	H	α-helix	trans	-58	-43.8	175.8	0	0	0	0	0	112	T39 V40 L41 L46 C47 V260 L289	T39-A43 PolarHBondContact O-N 3.46Å; V40-A43 WeakPolarHBondContact O-CB 3.39Å; V40-A43 PolarHBondContact O-N 3.16Å; L41-A43 PolarHBondContact O-N 3.14Å; A43-L46 PolarHBondContact O-N 3.47Å; A43-C47 PolarHBondContact O-N 2.91Å; A43-C47 VanDerWaalsContact O-N 3.08Å; A43-V260 HydrophobicContact CB-CB 4.32Å; A43-V260 HydrophobicContact CB-CG1 3.46Å; A43-V260 VanDerWaalsContact CB-CG1 3.46Å; A43-L289 HydrophobicContact CB-CD1 4.14Å
44	G	90.4	Very high	88.5	Confident	0 Å²	0	24.3 Å²	24.3	0%	0	12%	0.121	C	C	.	.	H	α-helix	trans	-62.8	-43.3	174.8	0	0	0	0	0	111.9	V40 L41 G42 L46 C47 G48 G292 C293	V40-G44 PolarHBondContact O-N 3.2Å; L41-G44 CarbonylContact O-C 3.56Å; L41-G44 PolarHBondContact O-N 3.5Å; G42-G44 VanDerWaalsContact C-N 3.31Å; G42-G44 PolarHBondContact O-N 2.89Å; G44-L46 VanDerWaalsContact C-N 3.34Å; G44-L46 PolarHBondContact O-N 3.28Å; G44-C47 PolarHBondContact O-N 3.11Å; G44-G48 PolarHBondContact O-N 3.25Å; G44-G292 CarbonylContact C-O 3.42Å; G44-G292 CarbonylContact O-C 3.6Å; G44-C293 WeakPolarHBondContact O-CA 3.37Å; G44-C293 PolarHBondContact O-N 3.17Å; G44-C293 PolarHBondContact O-SG 3.03Å
45	L	90	Very high	88.8	Confident	13 Å²	13	17.9 Å²	17.9	7%	0.068	10%	0.1	C	C	.	.	H	α-helix	trans	-58.3	-45.2	175	-71.8	170	0	0	0	110.9	L41 G42 T49 P186 F189 G292 I295 P296	L41-L45 HydrophobicContact CG-CD1 4.4Å; L41-L45 WeakPolarHBondContact O-CG 3.4Å; L41-L45 PolarHBondContact O-N 3.35Å; G42-L45 WeakPolarHBondContact O-CB 3.44Å; G42-L45 PolarHBondContact O-N 3.21Å; G42-L45 VanDerWaalsContact O-N 3.13Å; L45-T49 WeakPolarHBondContact O-CB 3.35Å; L45-T49 PolarHBondContact O-N 2.8Å; L45-T49 PolarHBondContact O-OG1 3.44Å; L45-P186 HydrophobicContact CB-CB 4.31Å; L45-P186 HydrophobicContact CD2-CB 4.46Å; L45-F189 HydrophobicContact CD1-CD1 3.66Å; L45-F189 HydrophobicContact CD1-CE1 4.05Å; L45-F189 HydrophobicContact CD1-CG 4.49Å; L45-G292 WeakPolarHBondContact CA-O 3.31Å; L45-G292 WeakPolarHBondContact CD2-O 3.48Å; L45-G292 PolarHBondContact N-O 3.23Å; L45-I295 HydrophobicContact CD2-CB 3.83Å; L45-I295 HydrophobicContact CD2-CD1 4.15Å; L45-I295 HydrophobicContact CD2-CG2 3.79Å; L45-P296 HydrophobicContact CD2-CG 4.08Å
46	L	87.1	Confident	89	Confident	1 Å²	1	19.1 Å²	19.1	1%	0.005	11%	0.11	C	C	.	.	H	α-helix	trans	-60.5	-48.3	177.3	-55.8	-179.8	0	0	0	111.4	G42 A43 G44 A50 A187 F252 A256 V260	G42-L46 WeakPolarHBondContact O-CG 3.46Å; G42-L46 PolarHBondContact O-N 3.29Å; A43-L46 PolarHBondContact O-N 3.47Å; G44-L46 VanDerWaalsContact C-N 3.34Å; G44-L46 PolarHBondContact O-N 3.28Å; L46-A50 PolarHBondContact O-N 3.25Å; L46-A187 HydrophobicContact CD2-CB 4.33Å; L46-F252 HydrophobicContact CB-CE1 4.09Å; L46-F252 HydrophobicContact CB-CE2 4.38Å; L46-F252 HydrophobicContact CB-CZ 3.85Å; L46-F252 HydrophobicContact CD2-CE1 4.28Å; L46-F252 HydrophobicContact CD2-CE2 3.69Å; L46-F252 HydrophobicContact CD2-CZ 3.29Å; L46-F252 HydrophobicContact CG-CE2 4.46Å; L46-F252 HydrophobicContact CG-CZ 4.1Å; L46-F252 WeakPolarHBondContact O-CD1 3.01Å; L46-F252 WeakPolarHBondContact O-CE1 3.36Å; L46-A256 HydrophobicContact CB-CB 3.94Å; L46-V260 HydrophobicContact CD1-CB 4.34Å; L46-V260 HydrophobicContact CD1-CG1 4.36Å; L46-V260 HydrophobicContact CD1-CG2 3.77Å
47	C	89.2	Confident	89	Confident	33 Å²	33	18.8 Å²	18.8	22%	0.223	11%	0.109	C	C	.	.	H	α-helix	trans	-64.6	-50.7	-179.3	-174.7	0	0	0	0	112.5	A43 G44 T49 A50 L51 A256	A43-C47 PolarHBondContact O-N 2.91Å; A43-C47 VanDerWaalsContact O-N 3.08Å; G44-C47 PolarHBondContact O-N 3.11Å; C47-T49 VanDerWaalsContact C-N 3.29Å; C47-T49 PolarHBondContact O-N 3.39Å; C47-A50 PolarHBondContact O-N 3.38Å; C47-L51 PolarHBondContact O-N 3.39Å; C47-A256 HydrophobicContact CB-CB 4.36Å
48	G	89.9	Confident	89	Confident	6 Å²	6	16.5 Å²	16.5	6%	0.062	10%	0.097	C	C	.	.	H	α-helix	trans	-62	-39	179	0	0	0	0	0	112	G44 L51 A52	G44-G48 PolarHBondContact O-N 3.25Å; G48-L51 PolarHBondContact O-N 3.48Å; G48-A52 WeakPolarHBondContact O-CA 3.5Å; G48-A52 WeakPolarHBondContact O-CB 3.44Å; G48-A52 PolarHBondContact O-N 3.4Å
49	T	88.4	Confident	89	Confident	0 Å²	0	17 Å²	17	0%	0	10%	0.1	C	C	.	.	H	α-helix	trans	-63.6	-46.2	177.1	-66.5	0	0	0	0	111.7	L45 C47 L51 V53 I54 H183 F252 P296	L45-T49 WeakPolarHBondContact O-CB 3.35Å; L45-T49 PolarHBondContact O-N 2.8Å; L45-T49 PolarHBondContact O-OG1 3.44Å; C47-T49 VanDerWaalsContact C-N 3.29Å; C47-T49 PolarHBondContact O-N 3.39Å; T49-L51 VanDerWaalsContact C-N 3.32Å; T49-L51 PolarHBondContact O-N 2.82Å; T49-V53 HydrophobicContact CG2-CB 4.49Å; T49-V53 WeakPolarHBondContact O-CA 3.41Å; T49-V53 WeakPolarHBondContact O-CB 3.46Å; T49-V53 PolarHBondContact O-N 3.18Å; T49-I54 HydrophobicContact CG2-CD1 4.4Å; T49-I54 HydrophobicContact CG2-CG1 4.39Å; T49-I54 PolarHBondContact O-N 3.28Å; T49-I54 VanDerWaalsContact O-N 3.15Å; T49-H183 VanDerWaalsContact CG2-CA 3.45Å; T49-H183 HydrophobicContact CG2-CB 3.02Å; T49-F252 HydrophobicContact CG2-CE1 3.95Å; T49-P296 WeakPolarHBondContact OG1-CG 3.02Å
50	A	89.1	Confident	89	Confident	0 Å²	0	21.3 Å²	21.3	0%	0	12%	0.12	C	C	.	.	I	π-helix	trans	-55.5	-48.9	176.5	0	0	0	0	0	111.5	L46 C47 I54 V55 F252 L253	L46-A50 PolarHBondContact O-N 3.25Å; C47-A50 PolarHBondContact O-N 3.38Å; A50-I54 PolarHBondContact O-N 3.13Å; A50-V55 WeakPolarHBondContact O-CG2 3.46Å; A50-V55 PolarHBondContact O-N 2.94Å; A50-F252 HydrophobicContact CB-CB 4.49Å; A50-F252 HydrophobicContact CB-CD1 3.79Å; A50-L253 HydrophobicContact CB-CD1 4.28Å; A50-L253 HydrophobicContact CB-CG 3.85Å
51	L	90.9	Very high	88.7	Confident	96 Å²	96	21.6 Å²	21.6	50%	0.503	12%	0.122	S	C	.	.	I	π-helix	trans	-81	-33.4	-172	-66.8	175	0	0	0	114.3	C47 G48 T49 P56 L253	C47-L51 PolarHBondContact O-N 3.39Å; G48-L51 PolarHBondContact O-N 3.48Å; T49-L51 VanDerWaalsContact C-N 3.32Å; T49-L51 PolarHBondContact O-N 2.82Å; L51-P56 WeakPolarHBondContact O-CD 3.19Å; L51-L253 HydrophobicContact CD2-CD1 4.22Å; L51-L253 HydrophobicContact CD2-CD2 4.07Å; L51-L253 HydrophobicContact CG-CD2 4.33Å
52	A	89.4	Confident	88.4	Confident	12 Å²	12	19.9 Å²	19.9	10%	0.099	11%	0.113	C	C	.	.	I	π-helix	trans	-103.9	-11.9	-173	0	0	0	0	0	114.3	G48 L297 S300	G48-A52 WeakPolarHBondContact O-CA 3.5Å; G48-A52 WeakPolarHBondContact O-CB 3.44Å; G48-A52 PolarHBondContact O-N 3.4Å; A52-L297 HydrophobicContact CB-CB 4.01Å; A52-L297 HydrophobicContact CB-CD1 3.85Å; A52-S300 WeakPolarHBondContact O-CB 3.36Å; A52-S300 PolarHBondContact O-OG 3.35Å
53	V	87.4	Confident	88.1	Confident	2 Å²	2	22.9 Å²	22.9	1%	0.012	13%	0.125	C	C	.	.	I	π-helix	trans	-133.4	-25.7	-175.5	-169.9	0	0	0	0	113.9	T49 E57 L182 H183 P296	T49-V53 HydrophobicContact CG2-CB 4.49Å; T49-V53 WeakPolarHBondContact O-CA 3.41Å; T49-V53 WeakPolarHBondContact O-CB 3.46Å; T49-V53 PolarHBondContact O-N 3.18Å; V53-E57 VanDerWaalsContact C-CD 3.49Å; V53-E57 VanDerWaalsContact CA-OE2 3.23Å; V53-E57 WeakPolarHBondContact CA-OE2 3.28Å; V53-E57 WeakPolarHBondContact O-CB 3.36Å; V53-E57 WeakPolarHBondContact O-CG 3.37Å; V53-L182 HydrophobicContact CG1-CB 4.03Å; V53-H183 HydrophobicContact CB-CB 4.3Å; V53-H183 HydrophobicContact CG1-CB 3.97Å; V53-P296 HydrophobicContact CG2-CB 3.87Å
54	I	88.8	Confident	87.6	Confident	1 Å²	1	25.3 Å²	25.3	1%	0.005	14%	0.136	C	C	.	.	I	π-helix	trans	-99.5	-46	-179.4	-46.2	-175.7	0	0	0	110.5	T49 A50 G58 H183 M245 A249 F252	T49-I54 HydrophobicContact CG2-CD1 4.4Å; T49-I54 HydrophobicContact CG2-CG1 4.39Å; T49-I54 PolarHBondContact O-N 3.28Å; T49-I54 VanDerWaalsContact O-N 3.15Å; A50-I54 PolarHBondContact O-N 3.13Å; I54-G58 PolarHBondContact O-N 3.03Å; I54-H183 HydrophobicContact CD1-CB 4.23Å; I54-H183 HydrophobicContact CG1-CB 4Å; I54-M245 WeakPolarHBondContact CG2-O 2.99Å; I54-A249 HydrophobicContact CB-CB 3.88Å; I54-A249 HydrophobicContact CG2-CB 3.63Å; I54-F252 HydrophobicContact CD1-CD1 3.86Å; I54-F252 HydrophobicContact CD1-CE1 4.38Å; I54-F252 HydrophobicContact CD1-CG 4.48Å
55	V	92	Very high	86.5	Confident	28 Å²	28	27.3 Å²	27.3	17%	0.17	15%	0.146	C	C	.	.	H	α-helix	trans	-61.6	-54.2	177.2	173.5	0	0	0	0	111.5	A50 E57 G58 V59 L110 L246 A249	A50-V55 WeakPolarHBondContact O-CG2 3.46Å; A50-V55 PolarHBondContact O-N 2.94Å; V55-E57 VanDerWaalsContact C-N 3.31Å; V55-E57 PolarHBondContact O-N 3.47Å; V55-G58 PolarHBondContact O-N 2.81Å; V55-V59 HydrophobicContact CG1-CG2 4.31Å; V55-V59 WeakPolarHBondContact O-CB 3.35Å; V55-V59 VanDerWaalsContact O-CG2 3.25Å; V55-V59 WeakPolarHBondContact O-CG2 3.22Å; V55-V59 PolarHBondContact O-N 3.25Å; V55-L110 HydrophobicContact CG2-CD1 4.49Å; V55-L110 HydrophobicContact CG2-CD2 3.83Å; V55-L246 HydrophobicContact CG1-CD2 4.47Å; V55-A249 HydrophobicContact CG2-CB 3.77Å
56	P	89.3	Confident	85.5	Confident	54 Å²	54	29.2 Å²	29.2	35%	0.351	16%	0.156	S	C	.	.	H	α-helix	trans	-62	-40.1	-174.9	-19.8	33.3	0	0	0	112.4	L51 V59 H60	L51-P56 WeakPolarHBondContact O-CD 3.19Å; P56-V59 WeakPolarHBondContact O-CB 3.23Å; P56-V59 PolarHBondContact O-N 3.47Å; P56-H60 WeakPolarHBondContact O-CB 3.34Å; P56-H60 PolarHBondContact O-N 3.18Å
57	E	85.8	Confident	84.4	Confident	39 Å²	39	34.3 Å²	34.3	18%	0.182	18%	0.183	C	C	.	.	H	α-helix	trans	-72.7	-39.5	-179.6	-73.5	82.4	157.2	0	0	111.5	V53 V55 V59 H60 A61 A179	V53-E57 VanDerWaalsContact C-CD 3.49Å; V53-E57 VanDerWaalsContact CA-OE2 3.23Å; V53-E57 WeakPolarHBondContact CA-OE2 3.28Å; V53-E57 WeakPolarHBondContact O-CB 3.36Å; V53-E57 WeakPolarHBondContact O-CG 3.37Å; V55-E57 VanDerWaalsContact C-N 3.31Å; V55-E57 PolarHBondContact O-N 3.47Å; E57-V59 VanDerWaalsContact C-N 3.31Å; E57-V59 PolarHBondContact O-N 2.83Å; E57-H60 PolarHBondContact O-N 3.17Å; E57-A61 PolarHBondContact O-N 2.88Å; E57-A179 HydrophobicContact CB-CB 4.15Å; E57-A179 HydrophobicContact CG-CB 3.81Å
58	G	88.5	Confident	83.1	Confident	0 Å²	0	36.6 Å²	36.6	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-60	-41	170.4	0	0	0	0	0	112.5	I54 V55 L62 G242	I54-G58 PolarHBondContact O-N 3.03Å; V55-G58 PolarHBondContact O-N 2.81Å; G58-L62 WeakPolarHBondContact O-CB 3.4Å; G58-L62 PolarHBondContact O-N 3.4Å; G58-L62 VanDerWaalsContact O-N 3.15Å; G58-G242 WeakPolarHBondContact O-CA 3.03Å
59	V	90.1	Very high	81.4	Confident	32 Å²	32	38.6 Å²	38.6	19%	0.194	21%	0.211	C	C	.	.	H	α-helix	trans	-64.3	-48.7	172.2	173	0	0	0	0	110.3	V55 P56 E57 A61 L62 Y63 I106 L246	V55-V59 HydrophobicContact CG1-CG2 4.31Å; V55-V59 WeakPolarHBondContact O-CB 3.35Å; V55-V59 VanDerWaalsContact O-CG2 3.25Å; V55-V59 WeakPolarHBondContact O-CG2 3.22Å; V55-V59 PolarHBondContact O-N 3.25Å; P56-V59 WeakPolarHBondContact O-CB 3.23Å; P56-V59 PolarHBondContact O-N 3.47Å; E57-V59 VanDerWaalsContact C-N 3.31Å; E57-V59 PolarHBondContact O-N 2.83Å; V59-A61 PolarHBondContact O-N 3.48Å; V59-L62 WeakPolarHBondContact O-CA 3.44Å; V59-L62 VanDerWaalsContact O-CB 3.3Å; V59-L62 WeakPolarHBondContact O-CB 3.39Å; V59-L62 PolarHBondContact O-N 3.35Å; V59-L62 VanDerWaalsContact O-N 3.08Å; V59-Y63 HydrophobicContact CG1-CD2 3.57Å; V59-Y63 HydrophobicContact CG1-CE2 3.49Å; V59-Y63 VanDerWaalsContact CG1-CE2 3.49Å; V59-Y63 VanDerWaalsContact O-CD2 3.31Å; V59-Y63 WeakPolarHBondContact O-CD2 3.47Å; V59-Y63 PolarHBondContact O-N 2.93Å; V59-I106 HydrophobicContact CB-CD1 4.38Å; V59-I106 HydrophobicContact CG1-CD1 3.88Å; V59-I106 HydrophobicContact CG2-CD1 3.7Å; V59-I106 HydrophobicContact CG2-CG1 3.96Å; V59-I106 HydrophobicContact CG2-CG2 3.89Å; V59-L246 HydrophobicContact CG2-CD2 4.03Å
60	H	86.6	Confident	79.6	Confident	91 Å²	91	43.5 Å²	43.5	42%	0.421	23%	0.232	S	C	.	.	H	α-helix	trans	-57.8	-49.6	-178.6	-177.8	56.4	0	0	0	112.2	P56 E57 L62 Y63 E64	P56-H60 WeakPolarHBondContact O-CB 3.34Å; P56-H60 PolarHBondContact O-N 3.18Å; E57-H60 PolarHBondContact O-N 3.17Å; H60-L62 PolarHBondContact O-N 3.41Å; H60-Y63 PolarHBondContact O-N 3.11Å; H60-E64 IonicContact CE1-OE1 3.63Å; H60-E64 PolarHBondContact CE1-OE1 3.35Å; H60-E64 VanDerWaalsContact CE1-OE1 3.28Å; H60-E64 IonicContact NE2-OE1 3.21Å; H60-E64 PolarHBondContact NE2-OE1 2.91Å; H60-E64 VanDerWaalsContact NE2-OE1 3.14Å; H60-E64 IonicContact NE2-OE2 3.45Å; H60-E64 PolarHBondContact O-N 3.02Å
61	A	82.7	Confident	77.4	Confident	6 Å²	6	50.8 Å²	50.8	5%	0.05	27%	0.266	C	S	.	.	H	α-helix	trans	-61.6	-33.1	176.1	0	0	0	0	0	112.8	E57 V59 Y63 D65 T241 M245	E57-A61 PolarHBondContact O-N 2.88Å; V59-A61 PolarHBondContact O-N 3.48Å; A61-Y63 VanDerWaalsContact C-N 3.34Å; A61-D65 PolarHBondContact O-N 3.41Å; A61-T241 HydrophobicContact CB-CG2 4.41Å; A61-M245 HydrophobicContact CB-CE 3.21Å
62	L	84.3	Confident	75	Confident	0 Å²	0	54.2 Å²	54.2	0%	0	28%	0.279	C	S	.	.	H	α-helix	trans	-66.9	-35.1	174.5	-168.9	77.7	0	0	0	112.1	G58 V59 H60 L102 I106 N239 V243 L246	G58-L62 WeakPolarHBondContact O-CB 3.4Å; G58-L62 PolarHBondContact O-N 3.4Å; G58-L62 VanDerWaalsContact O-N 3.15Å; V59-L62 WeakPolarHBondContact O-CA 3.44Å; V59-L62 VanDerWaalsContact O-CB 3.3Å; V59-L62 WeakPolarHBondContact O-CB 3.39Å; V59-L62 PolarHBondContact O-N 3.35Å; V59-L62 VanDerWaalsContact O-N 3.08Å; H60-L62 PolarHBondContact O-N 3.41Å; L62-L102 HydrophobicContact CD2-CD1 4.17Å; L62-L102 HydrophobicContact CD2-CD2 4.32Å; L62-L102 HydrophobicContact CD2-CG 3.84Å; L62-L102 HydrophobicContact CG-CD1 4.15Å; L62-L102 HydrophobicContact CG-CG 4.29Å; L62-I106 HydrophobicContact CD2-CD1 4.41Å; L62-I106 HydrophobicContact CD2-CG1 3.64Å; L62-N239 HydrophobicContact CD1-CB 3.45Å; L62-N239 VanDerWaalsContact CD1-CB 3.45Å; L62-N239 VanDerWaalsContact CD1-ND2 3.31Å; L62-N239 WeakPolarHBondContact CD1-ND2 3.41Å; L62-N239 PolarHBondContact O-ND2 3.48Å; L62-V243 HydrophobicContact CD1-CG2 3.95Å; L62-L246 HydrophobicContact CD2-CD1 4.14Å
63	Y	83	Confident	72.7	Confident	64 Å²	64	58.4 Å²	58.4	25%	0.251	31%	0.305	S	S	.	.	H	α-helix	trans	-77.6	-39.5	177	-86.7	-89.4	0	0	0	112.2	V59 H60 A61 I66 L67 H99 L102 H103 I106	V59-Y63 HydrophobicContact CG1-CD2 3.57Å; V59-Y63 HydrophobicContact CG1-CE2 3.49Å; V59-Y63 VanDerWaalsContact CG1-CE2 3.49Å; V59-Y63 VanDerWaalsContact O-CD2 3.31Å; V59-Y63 WeakPolarHBondContact O-CD2 3.47Å; V59-Y63 PolarHBondContact O-N 2.93Å; H60-Y63 PolarHBondContact O-N 3.11Å; A61-Y63 VanDerWaalsContact C-N 3.34Å; Y63-I66 PolarHBondContact O-N 3.04Å; Y63-L67 WeakPolarHBondContact O-CG 3.21Å; Y63-L67 PolarHBondContact O-N 3.48Å; Y63-L67 VanDerWaalsContact O-N 3.14Å; Y63-H99 AromaticContact CE1-ND1 4Å; Y63-L102 HydrophobicContact CD1-CD2 3.43Å; Y63-L102 VanDerWaalsContact CD1-CD2 3.43Å; Y63-L102 HydrophobicContact CD2-CD2 3.36Å; Y63-L102 HydrophobicContact CE1-CD2 3.24Å; Y63-L102 HydrophobicContact CE2-CD2 3.17Å; Y63-L102 HydrophobicContact CE2-CG 4.49Å; Y63-L102 HydrophobicContact CG-CD2 3.49Å; Y63-L102 VanDerWaalsContact CG-CD2 3.49Å; Y63-H103 PolarHBondContact OH-CE1 3.01Å; Y63-I106 HydrophobicContact CE2-CD1 4.37Å
64	E	76.3	Confident	70.3	Confident	54 Å²	54	62.6 Å²	62.6	25%	0.252	34%	0.34	S	S	.	.	H	α-helix	trans	-62.2	-48.6	180	-73.7	-166	143.8	0	0	112.2	H60 I66 L67 E68	H60-E64 IonicContact CE1-OE1 3.63Å; H60-E64 PolarHBondContact CE1-OE1 3.35Å; H60-E64 VanDerWaalsContact CE1-OE1 3.28Å; H60-E64 IonicContact NE2-OE1 3.21Å; H60-E64 PolarHBondContact NE2-OE1 2.91Å; H60-E64 VanDerWaalsContact NE2-OE1 3.14Å; H60-E64 IonicContact NE2-OE2 3.45Å; H60-E64 PolarHBondContact O-N 3.02Å; E64-I66 PolarHBondContact O-N 3.33Å; E64-I66 VanDerWaalsContact O-N 3.07Å; E64-L67 PolarHBondContact O-N 3.47Å; E64-L67 VanDerWaalsContact O-N 3.11Å; E64-E68 WeakPolarHBondContact O-CG 3.4Å; E64-E68 PolarHBondContact O-N 2.98Å
65	D	68.4	Low	67.7	Low	42 Å²	42	67.5 Å²	67.5	23%	0.225	38%	0.375	C	S	.	.	H	α-helix	trans	-54.5	-33.2	179.3	-84.2	-1.6	0	0	0	112.5	A61 G69 N239	A61-D65 PolarHBondContact O-N 3.41Å; D65-G69 PolarHBondContact O-N 2.92Å; D65-N239 HydrophobicContact CB-CB 4.25Å; D65-N239 WeakPolarHBondContact OD2-CA 3.46Å
66	I	67.3	Low	65.1	Low	52 Å²	52	75.5 Å²	75.5	27%	0.267	41%	0.41	S	S	.	.	H	α-helix	trans	-83.6	-36.5	-179.6	-74.5	163.7	0	0	0	112.8	Y63 E64 E68 G69 K70 L102 N239	Y63-I66 PolarHBondContact O-N 3.04Å; E64-I66 PolarHBondContact O-N 3.33Å; E64-I66 VanDerWaalsContact O-N 3.07Å; I66-E68 PolarHBondContact O-N 3.29Å; I66-G69 PolarHBondContact O-N 3.45Å; I66-K70 WeakPolarHBondContact O-CG 3.24Å; I66-K70 PolarHBondContact O-N 3.3Å; I66-L102 HydrophobicContact CD1-CD1 3.03Å; I66-L102 HydrophobicContact CG1-CD1 4.49Å; I66-N239 WeakPolarHBondContact CD1-ND2 3.2Å; I66-N239 WeakPolarHBondContact CG1-ND2 3.44Å
67	L	65	Low	62.7	Low	109 Å²	109	78.6 Å²	78.6	57%	0.571	43%	0.427	S	S	*	.	H	α-helix	trans	-65.1	-34	174.9	-70.1	174.9	0	0	0	111	Y63 E64 H71	Y63-L67 WeakPolarHBondContact O-CG 3.21Å; Y63-L67 PolarHBondContact O-N 3.48Å; Y63-L67 VanDerWaalsContact O-N 3.14Å; E64-L67 PolarHBondContact O-N 3.47Å; E64-L67 VanDerWaalsContact O-N 3.11Å; L67-H71 PolarHBondContact O-ND1 2.97Å
68	E	62.3	Low	60.3	Low	80 Å²	80	85.4 Å²	85.4	37%	0.374	46%	0.46	S	S	.	.	H	α-helix	trans	-73.6	-41.6	173.1	-66	-166	146.1	0	0	112.3	E64 I66 K70 H71 Q169	E64-E68 WeakPolarHBondContact O-CG 3.4Å; E64-E68 PolarHBondContact O-N 2.98Å; I66-E68 PolarHBondContact O-N 3.29Å; E68-K70 PolarHBondContact O-N 2.99Å; E68-H71 PolarHBondContact O-N 3.47Å; E68-H71 VanDerWaalsContact O-N 3.08Å; E68-Q169 PolarHBondContact OE1-NE2 3.42Å; E68-Q169 PolarHBondContact OE1-OE1 3.27Å; E68-Q169 PolarHBondContact OE2-NE2 3.3Å; E68-Q169 PolarHBondContact OE2-OE1 3.01Å
69	G	54.3	Low	57.8	Low	49 Å²	49	97.1 Å²	97.1	51%	0.505	50%	0.504	S	S	.	.	H	α-helix	trans	-59.1	-28.9	173.5	0	0	0	0	0	114.1	D65 I66	D65-G69 PolarHBondContact O-N 2.92Å; I66-G69 PolarHBondContact O-N 3.45Å
70	K	49.1	Very low	55.2	Low	102 Å²	102	101.6 Å²	101.6	44%	0.443	53%	0.531	S	S	.	.	T	Hydrogen-bonded Turn	trans	-77.8	-13.4	175.8	-78.7	-175.7	176.9	-178.3	0	115.2	I66 E68 H72 P73 D98	I66-K70 WeakPolarHBondContact O-CG 3.24Å; I66-K70 PolarHBondContact O-N 3.3Å; E68-K70 PolarHBondContact O-N 2.99Å; K70-H72 VanDerWaalsContact C-N 3.32Å; K70-P73 WeakPolarHBondContact O-CD 3.47Å; K70-D98 WeakPolarHBondContact CE-OD2 3.45Å; K70-D98 IonicContact NZ-OD2 3.71Å; K70-D98 PolarHBondContact NZ-OD2 3.47Å
71	H	43.7	Very low	52.8	Low	154 Å²	154	105.7 Å²	105.7	71%	0.713	55%	0.552	S	S	*	*	T	Hydrogen-bonded Turn	trans	-84.7	-6.1	173.6	-79.3	89.1	0	0	0	113.3	L67 E68	L67-H71 PolarHBondContact O-ND1 2.97Å; E68-H71 PolarHBondContact O-N 3.47Å; E68-H71 VanDerWaalsContact O-N 3.08Å
72	H	41	Very low	50.7	Low	168 Å²	168	115.1 Å²	115.1	78%	0.778	60%	0.595	S	S	*	*	S	Bend	trans	-113.5	44.9	177	-73.3	-70.6	0	0	0	115.5	K70	K70-H72 VanDerWaalsContact C-N 3.32Å
73	P	40	Very low	48.5	Very low	100 Å²	100	119.5 Å²	119.5	65%	0.649	63%	0.626	S	S	*	*	S	Bend	trans	-128.7	26.3	151.3	39.3	-26.9	0	0	0	113.2	K70	K70-P73 WeakPolarHBondContact O-CD 3.47Å
74	A	37.1	Very low	46.1	Very low	89 Å²	89	125.6 Å²	125.6	74%	0.736	66%	0.656	S	S	*	*	S	Bend	trans	-118.3	13	179.9	0	0	0	0	0	115
75	S	35.6	Very low	44.4	Very low	105 Å²	105	132 Å²	132	73%	0.734	68%	0.684	S	S	*	*	S	Bend	trans	-117.3	-2.1	-179.9	-173	0	0	0	0	115.5
76	E	37.2	Very low	43	Very low	195 Å²	195	136.5 Å²	136.5	91%	0.911	71%	0.712	S	S	*	*	S	Bend	trans	-122.2	11.6	-178	-95.2	-170.1	148.3	0	0	116.1
77	V	39.1	Very low	41.3	Very low	119 Å²	119	138.1 Å²	138.1	72%	0.721	73%	0.733	S	S	*	*	S	Bend	trans	-113	-12.1	170.4	-179.1	0	0	0	0	112.7	R79	V77-R79 PolarHBondContact O-N 2.92Å
78	Q	33.8	Very low	40.2	Very low	183 Å²	183	142.6 Å²	142.6	86%	0.855	75%	0.751	S	S	*	*	T	Hydrogen-bonded Turn	trans	-84.6	42.7	177.9	-158.6	72.5	18.5	0	0	113.3
79	R	36.3	Very low	39	Very low	246 Å²	246	145.7 Å²	145.7	93%	0.928	77%	0.769	S	S	*	*	T	Hydrogen-bonded Turn	trans	-140.1	9.1	166.2	-84.3	-153.9	-177.5	-158.5	2.7	115.6	V77	V77-R79 PolarHBondContact O-N 2.92Å
80	V	37	Very low	38.2	Very low	125 Å²	125	148.6 Å²	148.6	76%	0.758	78%	0.779	S	S	*	*	S	Bend	trans	-138.8	81.4	167.4	-172	0	0	0	0	108.2
81	M	34.8	Very low	37.7	Very low	178 Å²	178	150.1 Å²	150.1	88%	0.877	80%	0.796	S	S	*	*			trans	-175.8	59.1	155.4	-101.4	169.2	125.4	0	0	110.6	S83	M81-S83 VanDerWaalsContact C-N 3.35Å
82	E	39.3	Very low	37.3	Very low	204 Å²	204	148.7 Å²	148.7	95%	0.953	80%	0.798	S	S	*	*			trans	-87.4	85.6	141.7	-89.8	-173.9	158.8	0	0	106.7
83	S	37.2	Very low	37.3	Very low	91 Å²	91	147.8 Å²	147.8	64%	0.636	79%	0.794	S	S	*	*	S	Bend	trans	-180	132.5	140.6	-167.3	0	0	0	0	110.3	M81	M81-S83 VanDerWaalsContact C-N 3.35Å
84	E	34	Very low	37.3	Very low	192 Å²	192	150.5 Å²	150.5	90%	0.897	80%	0.798	S	S	*	*			trans	86.3	143.9	158.7	-108.4	172	127.7	0	0	120.7
85	K	39.2	Very low	37.8	Very low	190 Å²	190	153.5 Å²	153.5	83%	0.826	79%	0.791	S	S	*	*			trans	-105.5	148.5	-152.3	-113.3	-178.6	177.5	-179.2	0	110.9
86	V	39.9	Very low	38.3	Very low	136 Å²	136	151.4 Å²	151.4	82%	0.824	79%	0.786	S	S	*	*			trans	72.3	107.4	148.9	-177	0	0	0	0	117.9
87	A	32.2	Very low	39	Very low	85 Å²	85	148.6 Å²	148.6	70%	0.702	77%	0.772	S	S	*	*				-169.4	124.2	123.5	0	0	0	0	0	109.5
88	E	41.5	Very low	40	Very low	204 Å²	204	146.2 Å²	146.2	95%	0.953	76%	0.756	S	S	*	*			trans	-63.8	128.2	170	-71.5	175.2	154.7	0	0	110.2
89	I	37.1	Very low	41.6	Very low	144 Å²	144	141.8 Å²	141.8	74%	0.738	74%	0.735	S	S	*	*			trans	-131.9	131.1	167.4	-58.3	179.9	0	0	0	106.7	V91	I89-V91 PolarHBondContact O-N 3.09Å
90	P	38.2	Very low	43.3	Very low	110 Å²	110	134 Å²	134	71%	0.714	72%	0.718	S	S	*	*			trans	-70.5	129.3	-172.6	29.3	-33.1	0	0	0	110.3	V92	P90-V92 PolarHBondContact O-N 2.91Å
91	V	37	Very low	45	Very low	134 Å²	134	135.7 Å²	135.7	81%	0.812	71%	0.711	S	S	*	*			trans	-67.6	98.8	171.1	-177.6	0	0	0	0	108	I89 H93	I89-V91 PolarHBondContact O-N 3.09Å; V91-H93 PolarHBondContact O-N 3.39Å
92	V	35.3	Very low	47	Very low	124 Å²	124	127.7 Å²	127.7	75%	0.752	67%	0.671	S	S	*	*			trans	-77.4	111.6	168.3	179.5	0	0	0	0	107.2	P90 E94	P90-V92 PolarHBondContact O-N 2.91Å; V92-E94 PolarHBondContact O-N 3.34Å
93	H	41.8	Very low	49.1	Very low	150 Å²	150	123.2 Å²	123.2	69%	0.694	65%	0.65	S	S	*	*			trans	-52.7	105.9	172.5	-97.2	-93.8	0	0	0	111.5	V91 Y95	V91-H93 PolarHBondContact O-N 3.39Å; H93-Y95 VanDerWaalsContact C-N 3.27Å; H93-Y95 AromaticContact ND1-CD2 3.35Å; H93-Y95 WeakPolarHBondContact ND1-CD2 3.07Å; H93-Y95 AromaticContact ND1-CE2 3.77Å; H93-Y95 PolarHBondContact O-N 3.26Å
94	E	39	Very low	51.4	Low	157 Å²	157	121.4 Å²	121.4	73%	0.734	64%	0.641	S	S	*	*			trans	-90	52.1	172	-153.2	-174.6	168.3	0	0	111.2	V92	V92-E94 PolarHBondContact O-N 3.34Å
95	Y	48	Very low	53.9	Low	152 Å²	152	117.6 Å²	117.6	60%	0.596	62%	0.619	S	S	*	*			trans	-89.9	-8.5	-179.5	-99.3	-96.5	0	0	0	113.9	H93 H99	H93-Y95 VanDerWaalsContact C-N 3.27Å; H93-Y95 AromaticContact ND1-CD2 3.35Å; H93-Y95 WeakPolarHBondContact ND1-CD2 3.07Å; H93-Y95 AromaticContact ND1-CE2 3.77Å; H93-Y95 PolarHBondContact O-N 3.26Å; Y95-H99 PolarHBondContact O-CD2 2.94Å
96	G	46.7	Very low	56.4	Low	60 Å²	60	109.7 Å²	109.7	62%	0.619	59%	0.585	S	S	*	*	H	α-helix	trans	-84.2	-24.6	-172.6	0	0	0	0	0	115.8
97	H	52.6	Low	58.9	Low	136 Å²	136	104.9 Å²	104.9	63%	0.63	56%	0.563	S	S	*	*	H	α-helix	trans	-85.7	-31.4	-170.4	-81.3	-66.3	0	0	0	114.4	R101	H97-R101 PolarHBondContact O-N 3.35Å
98	D	59.2	Low	61.8	Low	69 Å²	69	104.7 Å²	104.7	37%	0.369	55%	0.553	S	S	.	*	H	α-helix	trans	-72.2	-39.5	-178	-89.1	-20.8	0	0	0	113.5	K70 S100 R101 L102	K70-D98 WeakPolarHBondContact CE-OD2 3.45Å; K70-D98 IonicContact NZ-OD2 3.71Å; K70-D98 PolarHBondContact NZ-OD2 3.47Å; D98-S100 VanDerWaalsContact C-N 3.29Å; D98-S100 PolarHBondContact O-N 3.43Å; D98-R101 PolarHBondContact O-N 2.82Å; D98-L102 PolarHBondContact O-N 2.85Å
99	H	66.7	Low	64.2	Low	91 Å²	91	95.3 Å²	95.3	42%	0.421	51%	0.51	S	S	.	.	H	α-helix	trans	-64.2	-35.9	179.6	-69.5	-59.2	0	0	0	112.2	Y63 Y95 L102 H103	Y63-H99 AromaticContact CE1-ND1 4Å; Y95-H99 PolarHBondContact O-CD2 2.94Å; H99-L102 PolarHBondContact O-N 3.36Å; H99-H103 PolarHBondContact O-CD2 3.28Å; H99-H103 PolarHBondContact O-N 2.88Å; H99-H103 VanDerWaalsContact O-N 3.07Å
100	S	71.8	Confident	67	Low	81 Å²	81	90.2 Å²	90.2	57%	0.566	48%	0.484	S	S	*	.	H	α-helix	trans	-64.8	-43.3	177	-175.6	0	0	0	0	112.3	D98 L102 A104	D98-S100 VanDerWaalsContact C-N 3.29Å; D98-S100 PolarHBondContact O-N 3.43Å; S100-L102 VanDerWaalsContact C-N 3.28Å; S100-L102 PolarHBondContact O-N 3.31Å; S100-A104 PolarHBondContact O-N 3.41Å
101	R	73.4	Confident	69.7	Low	161 Å²	161	89.2 Å²	89.2	61%	0.608	48%	0.476	S	S	*	.	H	α-helix	trans	-64.5	-36.2	175.3	-64	-175	83.4	178.7	3.4	111.3	H97 D98 A104 Y105	H97-R101 PolarHBondContact O-N 3.35Å; D98-R101 PolarHBondContact O-N 2.82Å; R101-A104 WeakPolarHBondContact O-CB 3.38Å; R101-A104 PolarHBondContact O-N 3.49Å; R101-Y105 WeakPolarHBondContact O-CD2 3.49Å; R101-Y105 PolarHBondContact O-N 3.16Å
102	L	77.8	Confident	72.4	Confident	10 Å²	10	87.6 Å²	87.6	5%	0.052	46%	0.463	C	S	.	.	H	α-helix	trans	-66.3	-46.2	179.7	-147.1	85.8	0	0	0	113.3	L62 Y63 I66 D98 H99 S100 A104 Y105 I106	L62-L102 HydrophobicContact CD2-CD1 4.17Å; L62-L102 HydrophobicContact CD2-CD2 4.32Å; L62-L102 HydrophobicContact CD2-CG 3.84Å; L62-L102 HydrophobicContact CG-CD1 4.15Å; L62-L102 HydrophobicContact CG-CG 4.29Å; Y63-L102 HydrophobicContact CD1-CD2 3.43Å; Y63-L102 VanDerWaalsContact CD1-CD2 3.43Å; Y63-L102 HydrophobicContact CD2-CD2 3.36Å; Y63-L102 HydrophobicContact CE1-CD2 3.24Å; Y63-L102 HydrophobicContact CE2-CD2 3.17Å; Y63-L102 HydrophobicContact CE2-CG 4.49Å; Y63-L102 HydrophobicContact CG-CD2 3.49Å; Y63-L102 VanDerWaalsContact CG-CD2 3.49Å; I66-L102 HydrophobicContact CD1-CD1 3.03Å; I66-L102 HydrophobicContact CG1-CD1 4.49Å; D98-L102 PolarHBondContact O-N 2.85Å; H99-L102 PolarHBondContact O-N 3.36Å; S100-L102 VanDerWaalsContact C-N 3.28Å; S100-L102 PolarHBondContact O-N 3.31Å; L102-A104 PolarHBondContact O-N 2.85Å; L102-Y105 PolarHBondContact O-N 3.5Å; L102-Y105 VanDerWaalsContact O-N 3.1Å; L102-I106 WeakPolarHBondContact O-CG1 3.36Å; L102-I106 PolarHBondContact O-N 3.19Å; L102-I106 VanDerWaalsContact O-N 3.07Å
103	H	83.6	Confident	75.2	Confident	111 Å²	111	81.7 Å²	81.7	51%	0.514	43%	0.427	S	S	.	.	H	α-helix	trans	-60	-33.7	174.4	-65.4	-50.9	0	0	0	111.7	Y63 H99 I106 G107	Y63-H103 PolarHBondContact OH-CE1 3.01Å; H99-H103 PolarHBondContact O-CD2 3.28Å; H99-H103 PolarHBondContact O-N 2.88Å; H99-H103 VanDerWaalsContact O-N 3.07Å; H103-I106 PolarHBondContact O-N 3.4Å; H103-G107 PolarHBondContact O-N 3Å
104	A	84.9	Confident	77.6	Confident	53 Å²	53	77.8 Å²	77.8	44%	0.438	41%	0.408	S	S	.	.	H	α-helix	trans	-65	-44.2	173.1	0	0	0	0	0	112.4	S100 R101 L102 I106 G107 V108	S100-A104 PolarHBondContact O-N 3.41Å; R101-A104 WeakPolarHBondContact O-CB 3.38Å; R101-A104 PolarHBondContact O-N 3.49Å; L102-A104 PolarHBondContact O-N 2.85Å; A104-I106 VanDerWaalsContact C-N 3.3Å; A104-I106 PolarHBondContact O-N 3.3Å; A104-G107 PolarHBondContact O-N 3.46Å; A104-V108 VanDerWaalsContact O-CB 3.3Å; A104-V108 WeakPolarHBondContact O-CB 3.38Å; A104-V108 WeakPolarHBondContact O-CG2 3.32Å; A104-V108 PolarHBondContact O-N 2.97Å
105	Y	86.4	Confident	80.2	Confident	112 Å²	112	73.3 Å²	73.3	44%	0.439	39%	0.391	S	S	.	.	H	α-helix	trans	-60.4	-38.8	175.4	-77.9	-71.7	0	0	0	112.5	R101 L102 S109	R101-Y105 WeakPolarHBondContact O-CD2 3.49Å; R101-Y105 PolarHBondContact O-N 3.16Å; L102-Y105 PolarHBondContact O-N 3.5Å; L102-Y105 VanDerWaalsContact O-N 3.1Å; Y105-S109 VanDerWaalsContact O-CB 3.26Å; Y105-S109 WeakPolarHBondContact O-CB 3.5Å; Y105-S109 PolarHBondContact O-N 2.88Å; Y105-S109 PolarHBondContact O-OG 3.47Å
106	I	91.4	Very high	82.3	Confident	23 Å²	23	70.3 Å²	70.3	12%	0.118	38%	0.381	C	S	.	.	H	α-helix	trans	-59.9	-54.8	177	-61.9	166.2	0	0	0	110.5	V59 L62 Y63 L102 H103 A104 L110 L246	V59-I106 HydrophobicContact CB-CD1 4.38Å; V59-I106 HydrophobicContact CG1-CD1 3.88Å; V59-I106 HydrophobicContact CG2-CD1 3.7Å; V59-I106 HydrophobicContact CG2-CG1 3.96Å; V59-I106 HydrophobicContact CG2-CG2 3.89Å; L62-I106 HydrophobicContact CD2-CD1 4.41Å; L62-I106 HydrophobicContact CD2-CG1 3.64Å; Y63-I106 HydrophobicContact CE2-CD1 4.37Å; L102-I106 WeakPolarHBondContact O-CG1 3.36Å; L102-I106 PolarHBondContact O-N 3.19Å; L102-I106 VanDerWaalsContact O-N 3.07Å; H103-I106 PolarHBondContact O-N 3.4Å; A104-I106 VanDerWaalsContact C-N 3.3Å; A104-I106 PolarHBondContact O-N 3.3Å; I106-L110 HydrophobicContact CG2-CD1 3.99Å; I106-L110 WeakPolarHBondContact O-CD1 3.49Å; I106-L110 WeakPolarHBondContact O-CG 3.38Å; I106-L110 PolarHBondContact O-N 3.19Å; I106-L246 HydrophobicContact CB-CD1 4.42Å; I106-L246 HydrophobicContact CG1-CD1 4.13Å; I106-L246 HydrophobicContact CG2-CD1 4.49Å; I106-L246 HydrophobicContact CG2-CD2 4.14Å
107	G	91.6	Very high	84.2	Confident	35 Å²	35	67.5 Å²	67.5	36%	0.361	35%	0.352	S	S	.	.	H	α-helix	trans	-63.2	-45.2	-179.2	0	0	0	0	0	112.9	H103 A104 L110 V111	H103-G107 PolarHBondContact O-N 3Å; A104-G107 PolarHBondContact O-N 3.46Å; G107-L110 PolarHBondContact O-N 2.93Å; G107-V111 WeakPolarHBondContact O-CB 3.36Å; G107-V111 VanDerWaalsContact O-CG2 3.3Å; G107-V111 WeakPolarHBondContact O-CG2 3.41Å; G107-V111 PolarHBondContact O-N 3.22Å
108	V	93	Very high	85.9	Confident	81 Å²	81	63.9 Å²	63.9	49%	0.491	34%	0.337	S	S	.	.	H	α-helix	trans	-63.7	-46	-178.8	170.1	0	0	0	0	111.1	A104 L110 V111 L112	A104-V108 VanDerWaalsContact O-CB 3.3Å; A104-V108 WeakPolarHBondContact O-CB 3.38Å; A104-V108 WeakPolarHBondContact O-CG2 3.32Å; A104-V108 PolarHBondContact O-N 2.97Å; V108-L110 PolarHBondContact O-N 3.22Å; V108-V111 PolarHBondContact O-N 3.04Å; V108-L112 HydrophobicContact CG1-CD1 3.68Å; V108-L112 HydrophobicContact CG1-CG 4.17Å; V108-L112 VanDerWaalsContact O-CB 3.3Å; V108-L112 WeakPolarHBondContact O-CB 3.43Å; V108-L112 VanDerWaalsContact O-CG 3.26Å; V108-L112 WeakPolarHBondContact O-CG 3.46Å; V108-L112 PolarHBondContact O-N 2.94Å
109	S	93.4	Very high	87.2	Confident	7 Å²	7	65 Å²	65	5%	0.049	34%	0.342	C	S	.	.	H	α-helix	trans	-62.4	-43.6	179	-62.8	0	0	0	0	112.1	Y105 L112 G113 F247	Y105-S109 VanDerWaalsContact O-CB 3.26Å; Y105-S109 WeakPolarHBondContact O-CB 3.5Å; Y105-S109 PolarHBondContact O-N 2.88Å; Y105-S109 PolarHBondContact O-OG 3.47Å; S109-L112 PolarHBondContact O-N 2.92Å; S109-G113 PolarHBondContact O-N 2.95Å; S109-F247 WeakPolarHBondContact O-CA 3.34Å
110	L	94.7	Very high	88	Confident	37 Å²	37	61.9 Å²	61.9	19%	0.194	33%	0.33	C	S	.	.	H	α-helix	trans	-61.6	-47.7	176.6	-74.1	167.3	0	0	0	112	V55 I106 G107 V108 G113 F114 L246 A249 G250	V55-L110 HydrophobicContact CG2-CD1 4.49Å; V55-L110 HydrophobicContact CG2-CD2 3.83Å; I106-L110 HydrophobicContact CG2-CD1 3.99Å; I106-L110 WeakPolarHBondContact O-CD1 3.49Å; I106-L110 WeakPolarHBondContact O-CG 3.38Å; I106-L110 PolarHBondContact O-N 3.19Å; G107-L110 PolarHBondContact O-N 2.93Å; V108-L110 PolarHBondContact O-N 3.22Å; L110-G113 PolarHBondContact O-N 3.05Å; L110-F114 PolarHBondContact O-N 3.38Å; L110-L246 HydrophobicContact CD1-CD2 4.48Å; L110-L246 HydrophobicContact CD2-CD2 4.34Å; L110-L246 VanDerWaalsContact CD2-O 3.26Å; L110-L246 WeakPolarHBondContact CD2-O 3.45Å; L110-L246 HydrophobicContact CG-CD2 4.27Å; L110-A249 HydrophobicContact CD2-CB 3.6Å; L110-G250 VanDerWaalsContact O-CA 3.31Å; L110-G250 WeakPolarHBondContact O-CA 3.48Å
111	V	95.4	Very high	88.4	Confident	90 Å²	90	58.9 Å²	58.9	55%	0.545	31%	0.307	S	S	.	.	H	α-helix	trans	-65.7	-42	179.6	172.2	0	0	0	0	110.9	G107 V108 G113 F114 V115	G107-V111 WeakPolarHBondContact O-CB 3.36Å; G107-V111 VanDerWaalsContact O-CG2 3.3Å; G107-V111 WeakPolarHBondContact O-CG2 3.41Å; G107-V111 PolarHBondContact O-N 3.22Å; V108-V111 PolarHBondContact O-N 3.04Å; V111-G113 VanDerWaalsContact C-N 3.33Å; V111-G113 PolarHBondContact O-N 2.74Å; V111-F114 PolarHBondContact O-N 2.99Å; V111-V115 HydrophobicContact CG1-CG2 4.07Å; V111-V115 WeakPolarHBondContact O-CB 3.47Å; V111-V115 VanDerWaalsContact O-CG2 3.31Å; V111-V115 WeakPolarHBondContact O-CG2 3.26Å; V111-V115 PolarHBondContact O-N 3Å
112	L	94.4	Very high	88.7	Confident	100 Å²	100	55.8 Å²	55.8	52%	0.524	30%	0.3	S	S	.	.	H	α-helix	trans	-61.8	-41.5	176.6	-76.6	175.7	0	0	0	111.7	V108 S109 F116 F247	V108-L112 HydrophobicContact CG1-CD1 3.68Å; V108-L112 HydrophobicContact CG1-CG 4.17Å; V108-L112 VanDerWaalsContact O-CB 3.3Å; V108-L112 WeakPolarHBondContact O-CB 3.43Å; V108-L112 VanDerWaalsContact O-CG 3.26Å; V108-L112 WeakPolarHBondContact O-CG 3.46Å; V108-L112 PolarHBondContact O-N 2.94Å; S109-L112 PolarHBondContact O-N 2.92Å; L112-F116 WeakPolarHBondContact O-CB 3.43Å; L112-F116 PolarHBondContact O-N 3.29Å; L112-F247 HydrophobicContact CB-CD2 4.31Å; L112-F247 HydrophobicContact CB-CE2 4.5Å
113	G	92.8	Very high	88.7	Confident	0 Å²	0	60.8 Å²	60.8	0%	0	33%	0.326	C	S	.	.	H	α-helix	trans	-60.9	-46.1	173.5	0	0	0	0	0	112.6	S109 L110 V111 F116 M117 F247 T251	S109-G113 PolarHBondContact O-N 2.95Å; L110-G113 PolarHBondContact O-N 3.05Å; V111-G113 VanDerWaalsContact C-N 3.33Å; V111-G113 PolarHBondContact O-N 2.74Å; G113-F116 PolarHBondContact O-N 3.4Å; G113-M117 PolarHBondContact O-N 3.4Å; G113-F247 VanDerWaalsContact CA-CD2 3.45Å; G113-F247 WeakPolarHBondContact CA-O 3.31Å; G113-T251 WeakPolarHBondContact O-CG2 3.37Å
114	F	93.3	Very high	87.9	Confident	67 Å²	67	56.9 Å²	56.9	29%	0.294	32%	0.315	S	S	.	.	H	α-helix	trans	-62.4	-49.1	178.2	-172.6	-82.3	0	0	0	112	L110 V111 M117 L118 G250 L253 Y254 V258	L110-F114 PolarHBondContact O-N 3.38Å; V111-F114 PolarHBondContact O-N 2.99Å; F114-M117 PolarHBondContact O-N 2.92Å; F114-L118 PolarHBondContact O-N 2.8Å; F114-G250 WeakPolarHBondContact CA-O 3.48Å; F114-L253 HydrophobicContact CD2-CB 4.45Å; F114-Y254 HydrophobicContact CD1-CD2 4.01Å; F114-Y254 HydrophobicContact CD2-CD2 4.21Å; F114-Y254 HydrophobicContact CD2-CG 4.5Å; F114-Y254 AromaticContact CE1-CD2 3.65Å; F114-Y254 HydrophobicContact CE1-CD2 3.65Å; F114-Y254 HydrophobicContact CE1-CE2 4.25Å; F114-Y254 AromaticContact CE2-CD2 3.87Å; F114-Y254 HydrophobicContact CE2-CD2 3.87Å; F114-Y254 HydrophobicContact CE2-CG 4.36Å; F114-Y254 HydrophobicContact CG-CD2 4.27Å; F114-Y254 AromaticContact CZ-CD2 3.58Å; F114-Y254 HydrophobicContact CZ-CD2 3.58Å; F114-Y254 HydrophobicContact CZ-CE2 4.34Å; F114-Y254 HydrophobicContact CZ-CG 4.49Å; F114-V258 HydrophobicContact CZ-CG2 4.29Å
115	V	93.2	Very high	86.9	Confident	63 Å²	63	56.7 Å²	56.7	38%	0.382	31%	0.311	S	S	.	.	H	α-helix	trans	-65.9	-39.7	179	172.1	0	0	0	0	111	V111 M117 L118 L119	V111-V115 HydrophobicContact CG1-CG2 4.07Å; V111-V115 WeakPolarHBondContact O-CB 3.47Å; V111-V115 VanDerWaalsContact O-CG2 3.31Å; V111-V115 WeakPolarHBondContact O-CG2 3.26Å; V111-V115 PolarHBondContact O-N 3Å; V115-M117 VanDerWaalsContact C-N 3.31Å; V115-M117 PolarHBondContact O-N 3.38Å; V115-L118 WeakPolarHBondContact O-CB 3.43Å; V115-L118 PolarHBondContact O-N 3.39Å; V115-L119 HydrophobicContact CG1-CD1 4.27Å; V115-L119 HydrophobicContact CG1-CG 4.38Å; V115-L119 WeakPolarHBondContact O-CG 3.33Å; V115-L119 PolarHBondContact O-N 3.17Å
116	F	91.6	Very high	85.4	Confident	89 Å²	89	55.4 Å²	55.4	39%	0.39	32%	0.318	S	S	.	.	H	α-helix	trans	-57.7	-47.4	175.2	-179.9	-97.8	0	0	0	110.7	L112 G113 L118 L119 V120 V152 F247	L112-F116 WeakPolarHBondContact O-CB 3.43Å; L112-F116 PolarHBondContact O-N 3.29Å; G113-F116 PolarHBondContact O-N 3.4Å; F116-L118 VanDerWaalsContact C-N 3.33Å; F116-L118 PolarHBondContact O-N 3.46Å; F116-L119 PolarHBondContact O-N 3.22Å; F116-V120 HydrophobicContact CD1-CG2 3.97Å; F116-V120 HydrophobicContact CE1-CG2 3.54Å; F116-V120 HydrophobicContact CE2-CG2 4.37Å; F116-V120 HydrophobicContact CZ-CG2 3.77Å; F116-V120 WeakPolarHBondContact O-CG2 3.23Å; F116-V120 PolarHBondContact O-N 3.26Å; F116-V152 HydrophobicContact CD1-CG1 3.93Å; F116-V152 HydrophobicContact CE1-CG1 3.47Å; F116-V152 VanDerWaalsContact CE1-CG1 3.47Å; F116-V152 HydrophobicContact CE1-CG2 4.45Å; F116-F247 HydrophobicContact CB-CE2 3.91Å; F116-F247 HydrophobicContact CB-CZ 3.77Å; F116-F247 HydrophobicContact CD1-CE1 4.37Å; F116-F247 AromaticContact CD1-CZ 3.69Å; F116-F247 HydrophobicContact CD1-CZ 3.69Å; F116-F247 HydrophobicContact CD2-CZ 4.37Å; F116-F247 HydrophobicContact CE1-CZ 4.39Å; F116-F247 HydrophobicContact CG-CE2 4.25Å; F116-F247 AromaticContact CG-CZ 3.67Å; F116-F247 HydrophobicContact CG-CZ 3.67Å
117	M	87.9	Confident	83.4	Confident	2 Å²	2	62.2 Å²	62.2	1%	0.01	35%	0.349	C	S	.	.	H	α-helix	trans	-65.1	-36.5	176.5	-90.7	-47.6	-50.2	0	0	113.5	G113 F114 V115 L119 V120 D121 G149 V152 T251 Y254 V255	G113-M117 PolarHBondContact O-N 3.4Å; F114-M117 PolarHBondContact O-N 2.92Å; V115-M117 VanDerWaalsContact C-N 3.31Å; V115-M117 PolarHBondContact O-N 3.38Å; M117-L119 VanDerWaalsContact C-N 3.33Å; M117-L119 PolarHBondContact O-N 3.34Å; M117-V120 HydrophobicContact CE-CB 4.26Å; M117-V120 HydrophobicContact CE-CG1 4.16Å; M117-V120 PolarHBondContact O-N 2.81Å; M117-V120 HydrophobicContact SD-CB 4.26Å; M117-V120 HydrophobicContact SD-CG1 4.35Å; M117-D121 WeakPolarHBondContact O-CB 3.47Å; M117-D121 PolarHBondContact O-N 3.32Å; M117-G149 WeakPolarHBondContact SD-CA 3.36Å; M117-V152 HydrophobicContact SD-CB 3.95Å; M117-V152 HydrophobicContact SD-CG1 3.77Å; M117-V152 HydrophobicContact SD-CG2 4.49Å; M117-T251 HydrophobicContact CG-CG2 3.74Å; M117-Y254 HydrophobicContact CB-CD1 3.7Å; M117-Y254 HydrophobicContact CB-CE1 4.45Å; M117-Y254 HydrophobicContact CB-CG 3.85Å; M117-Y254 HydrophobicContact CE-CD1 4.5Å; M117-V255 HydrophobicContact CE-CG2 4.4Å
118	L	87.5	Confident	81.3	Confident	60 Å²	60	64.9 Å²	64.9	31%	0.314	36%	0.358	S	S	.	.	H	α-helix	trans	-57	-48.3	170.6	-171.7	159.7	0	0	0	111.1	F114 V115 F116 D121 Q122 Y254	F114-L118 PolarHBondContact O-N 2.8Å; V115-L118 WeakPolarHBondContact O-CB 3.43Å; V115-L118 PolarHBondContact O-N 3.39Å; F116-L118 VanDerWaalsContact C-N 3.33Å; F116-L118 PolarHBondContact O-N 3.46Å; L118-D121 WeakPolarHBondContact O-CB 3.14Å; L118-D121 PolarHBondContact O-N 2.91Å; L118-Q122 HydrophobicContact CD2-CG 3.86Å; L118-Q122 VanDerWaalsContact O-CG 3.31Å; L118-Q122 WeakPolarHBondContact O-CG 3.44Å; L118-Q122 PolarHBondContact O-N 3.07Å; L118-Y254 VanDerWaalsContact CA-CZ 3.5Å; L118-Y254 HydrophobicContact CB-CD2 4.06Å; L118-Y254 HydrophobicContact CB-CE2 3.5Å; L118-Y254 VanDerWaalsContact CB-CE2 3.5Å; L118-Y254 HydrophobicContact CD1-CE2 4.09Å; L118-Y254 HydrophobicContact CG-CE2 3.82Å
119	L	86.8	Confident	78.9	Confident	92 Å²	92	69.6 Å²	69.6	48%	0.482	37%	0.374	S	S	.	.	H	α-helix	trans	-65.5	-42.9	180	-67.3	176.8	0	0	0	112.5	V115 F116 M117 D121 Q122 I123	V115-L119 HydrophobicContact CG1-CD1 4.27Å; V115-L119 HydrophobicContact CG1-CG 4.38Å; V115-L119 WeakPolarHBondContact O-CG 3.33Å; V115-L119 PolarHBondContact O-N 3.17Å; F116-L119 PolarHBondContact O-N 3.22Å; M117-L119 VanDerWaalsContact C-N 3.33Å; M117-L119 PolarHBondContact O-N 3.34Å; L119-D121 PolarHBondContact O-N 3.08Å; L119-Q122 PolarHBondContact O-N 2.59Å; L119-I123 WeakPolarHBondContact O-CB 3.14Å; L119-I123 WeakPolarHBondContact O-CD1 3.21Å; L119-I123 VanDerWaalsContact O-CG1 3.24Å; L119-I123 WeakPolarHBondContact O-CG1 3.08Å; L119-I123 PolarHBondContact O-N 3.15Å
120	V	83.9	Confident	76.4	Confident	25 Å²	25	74.6 Å²	74.6	15%	0.152	41%	0.409	C	S	.	.	H	α-helix	trans	-56	-42.8	174.3	168.3	0	0	0	0	110.3	F116 M117 G124 L148	F116-V120 HydrophobicContact CD1-CG2 3.97Å; F116-V120 HydrophobicContact CE1-CG2 3.54Å; F116-V120 HydrophobicContact CE2-CG2 4.37Å; F116-V120 HydrophobicContact CZ-CG2 3.77Å; F116-V120 WeakPolarHBondContact O-CG2 3.23Å; F116-V120 PolarHBondContact O-N 3.26Å; M117-V120 HydrophobicContact CE-CB 4.26Å; M117-V120 HydrophobicContact CE-CG1 4.16Å; M117-V120 PolarHBondContact O-N 2.81Å; M117-V120 HydrophobicContact SD-CB 4.26Å; M117-V120 HydrophobicContact SD-CG1 4.35Å; V120-G124 PolarHBondContact O-N 3.36Å; V120-L148 HydrophobicContact CG1-CD2 3.68Å; V120-L148 HydrophobicContact CG1-CG 3.93Å
121	D	78.9	Confident	74	Confident	19 Å²	19	78 Å²	78	10%	0.102	43%	0.432	C	S	.	.	H	α-helix	trans	-65.9	-48.5	178.8	173.4	39.8	0	0	0	112.4	M117 L118 L119 I123 G124 S125 T145 Y254 H259	M117-D121 WeakPolarHBondContact O-CB 3.47Å; M117-D121 PolarHBondContact O-N 3.32Å; L118-D121 WeakPolarHBondContact O-CB 3.14Å; L118-D121 PolarHBondContact O-N 2.91Å; L119-D121 PolarHBondContact O-N 3.08Å; D121-I123 PolarHBondContact O-N 3.37Å; D121-G124 PolarHBondContact O-N 3.33Å; D121-S125 PolarHBondContact O-N 3Å; D121-S125 PolarHBondContact O-OG 3.15Å; D121-T145 HydrophobicContact CB-CG2 3.65Å; D121-T145 WeakPolarHBondContact OD1-CG2 3.25Å; D121-Y254 HydrophobicContact CB-CE1 3.97Å; D121-Y254 PolarHBondContact OD2-OH 3.48Å; D121-H259 VanDerWaalsContact CG-CE1 3.44Å; D121-H259 IonicContact OD1-CE1 3.88Å; D121-H259 IonicContact OD1-NE2 3.63Å; D121-H259 PolarHBondContact OD1-NE2 3.05Å; D121-H259 IonicContact OD2-CE1 3.79Å; D121-H259 PolarHBondContact OD2-CE1 3.31Å; D121-H259 IonicContact OD2-NE2 3.66Å
122	Q	80.8	Confident	71.7	Confident	96 Å²	96	82.3 Å²	82.3	45%	0.449	45%	0.452	S	S	.	.	H	α-helix	trans	-60.9	-41.1	177.6	-65.8	-56.6	-44.6	0	0	113	L118 L119 S125 S126	L118-Q122 HydrophobicContact CD2-CG 3.86Å; L118-Q122 VanDerWaalsContact O-CG 3.31Å; L118-Q122 WeakPolarHBondContact O-CG 3.44Å; L118-Q122 PolarHBondContact O-N 3.07Å; L119-Q122 PolarHBondContact O-N 2.59Å; Q122-S125 PolarHBondContact O-OG 2.91Å; Q122-S126 WeakPolarHBondContact O-CB 3.49Å; Q122-S126 PolarHBondContact O-N 3.34Å; Q122-S126 PolarHBondContact O-OG 3.32Å
123	I	77.4	Confident	69.6	Low	115 Å²	115	81.9 Å²	81.9	59%	0.59	45%	0.45	S	S	*	.	H	α-helix	trans	-69.4	-42.9	178.5	-64.9	165	0	0	0	110	L119 D121 S125 S126 H127	L119-I123 WeakPolarHBondContact O-CB 3.14Å; L119-I123 WeakPolarHBondContact O-CD1 3.21Å; L119-I123 VanDerWaalsContact O-CG1 3.24Å; L119-I123 WeakPolarHBondContact O-CG1 3.08Å; L119-I123 PolarHBondContact O-N 3.15Å; D121-I123 PolarHBondContact O-N 3.37Å; I123-S125 VanDerWaalsContact C-N 3.32Å; I123-S125 PolarHBondContact O-N 2.86Å; I123-S126 PolarHBondContact O-N 2.94Å; I123-H127 PolarHBondContact O-N 3.34Å
124	G	67.3	Low	67.7	Low	28 Å²	28	86.4 Å²	86.4	29%	0.289	48%	0.479	S	S	.	.	H	α-helix	trans	-60.7	-38.4	177.2	0	0	0	0	0	113	V120 D121	V120-G124 PolarHBondContact O-N 3.36Å; D121-G124 PolarHBondContact O-N 3.33Å
125	S	63	Low	65.5	Low	50 Å²	50	91.2 Å²	91.2	35%	0.35	50%	0.503	S	S	.	.	H	α-helix	trans	-73.9	-25.7	176.2	62.7	0	0	0	0	113.8	D121 Q122 I123	D121-S125 PolarHBondContact O-N 3Å; D121-S125 PolarHBondContact O-OG 3.15Å; Q122-S125 PolarHBondContact O-OG 2.91Å; I123-S125 VanDerWaalsContact C-N 3.32Å; I123-S125 PolarHBondContact O-N 2.86Å
126	S	55.3	Low	63.1	Low	84 Å²	84	91.3 Å²	91.3	59%	0.587	51%	0.51	S	S	*	.	H	α-helix	trans	-82.7	-24.5	-173.3	-61.3	0	0	0	0	114.3	Q122 I123	Q122-S126 WeakPolarHBondContact O-CB 3.49Å; Q122-S126 PolarHBondContact O-N 3.34Å; Q122-S126 PolarHBondContact O-OG 3.32Å; I123-S126 PolarHBondContact O-N 2.94Å
127	H	49.3	Very low	60.9	Low	166 Å²	166	88.4 Å²	88.4	77%	0.769	50%	0.502	S	S	*	.	S	Bend	trans	-91	5.4	-169.6	-147	-61.7	0	0	0	115.1	I123	I123-H127 PolarHBondContact O-N 3.34Å
128	V	47.1	Very low	59	Low	91 Å²	91	98 Å²	98	55%	0.552	54%	0.539	S	S	*	.			trans	-125.4	65.4	179.5	-167.8	0	0	0	0	109.8
129	H	42.1	Very low	57	Low	180 Å²	180	97.3 Å²	97.3	83%	0.833	54%	0.539	S	S	*	.			trans	-107.6	78	172.6	-136.1	-35.7	0	0	0	108.9
130	S	42.2	Very low	55.2	Low	113 Å²	113	94.4 Å²	94.4	79%	0.79	53%	0.531	S	S	*	.			trans	-166.4	60.1	170	-72.6	0	0	0	0	112
131	T	44.5	Very low	53.8	Low	109 Å²	109	95.1 Å²	95.1	67%	0.669	53%	0.534	S	S	*	.			trans	-156.2	136.2	157.6	47.5	0	0	0	0	110.5	D133	T131-D133 VanDerWaalsContact C-N 3.25Å; T131-D133 PolarHBondContact O-N 2.93Å
132	D	46	Very low	52.7	Low	179 Å²	179	95.7 Å²	95.7	96%	0.957	54%	0.54	S	S	*	.	S	Bend	trans	-73.1	32.1	-168.7	-69.8	-43.8	0	0	0	116.7
133	D	51.8	Low	51.9	Low	92 Å²	92	93.1 Å²	93.1	49%	0.492	53%	0.527	S	S	.	.			trans	-141.2	101.9	175.5	-158.5	-17.1	0	0	0	113	T131 E135 A137	T131-D133 VanDerWaalsContact C-N 3.25Å; T131-D133 PolarHBondContact O-N 2.93Å; D133-E135 PolarHBondContact O-N 3.13Å; D133-A137 VanDerWaalsContact O-CB 3.29Å; D133-A137 WeakPolarHBondContact O-CB 3.3Å; D133-A137 PolarHBondContact O-N 2.86Å
134	P	52.5	Low	51.3	Low	95 Å²	95	92 Å²	92	62%	0.617	52%	0.521	S	S	*	.	H	α-helix	trans	-72.8	-19.2	-170.2	26.6	-33	0	0	0	114.9	R138	P134-R138 WeakPolarHBondContact O-CD 3.39Å; P134-R138 VanDerWaalsContact O-CG 3.25Å; P134-R138 WeakPolarHBondContact O-CG 3.38Å
135	E	46.4	Very low	51.4	Low	167 Å²	167	91 Å²	91	78%	0.78	51%	0.509	S	S	*	.	H	α-helix	trans	-88	-40.5	-177.6	-126.4	175.5	174.9	0	0	111.9	D133	D133-E135 PolarHBondContact O-N 3.13Å
136	A	43.8	Very low	51.6	Low	65 Å²	65	88.7 Å²	88.7	54%	0.537	49%	0.493	S	S	.	.	H	α-helix	trans	-73.1	-35.9	175.6	0	0	0	0	0	112.8	G140	A136-G140 PolarHBondContact O-N 3.48Å; A136-G140 VanDerWaalsContact O-N 3.11Å
137	A	44	Very low	52.4	Low	28 Å²	28	85.1 Å²	85.1	23%	0.231	47%	0.468	C	S	.	.	H	α-helix	trans	-67.2	-37.4	177.6	0	0	0	0	0	112.6	D133 G140 N141	D133-A137 VanDerWaalsContact O-CB 3.29Å; D133-A137 WeakPolarHBondContact O-CB 3.3Å; D133-A137 PolarHBondContact O-N 2.86Å; A137-G140 PolarHBondContact O-N 3.38Å; A137-N141 VanDerWaalsContact O-CB 3.3Å; A137-N141 WeakPolarHBondContact O-CB 2.98Å; A137-N141 PolarHBondContact O-N 2.89Å; A137-N141 PolarHBondContact O-OD1 3.3Å
138	R	47.9	Very low	53.8	Low	204 Å²	204	80.8 Å²	80.8	77%	0.77	45%	0.45	S	S	*	.	H	α-helix	trans	-63.9	-41.8	177.2	-80.7	177.3	170.4	178.6	-2.1	112.9	P134 S142	P134-R138 WeakPolarHBondContact O-CD 3.39Å; P134-R138 VanDerWaalsContact O-CG 3.25Å; P134-R138 WeakPolarHBondContact O-CG 3.38Å; R138-S142 PolarHBondContact O-N 3.1Å
139	S	47	Very low	55.3	Low	45 Å²	45	76.5 Å²	76.5	32%	0.315	42%	0.424	S	S	.	.	H	α-helix	trans	-71.3	-37.3	177.4	-168.5	0	0	0	0	112.2	S142 K143	S139-S142 PolarHBondContact O-OG 3.39Å; S139-K143 WeakPolarHBondContact O-CD 3.12Å; S139-K143 WeakPolarHBondContact O-CE 3.33Å; S139-K143 WeakPolarHBondContact O-CG 3.44Å; S139-K143 WeakPolarHBondContact OG-CE 3.29Å; S139-K143 PolarHBondContact OG-NZ 3.33Å
140	G	48.7	Very low	57	Low	31 Å²	31	68 Å²	68	32%	0.32	38%	0.384	S	S	.	.	H	α-helix	trans	-65.8	-39.1	175	0	0	0	0	0	113.4	A136 A137	A136-G140 PolarHBondContact O-N 3.48Å; A136-G140 VanDerWaalsContact O-N 3.11Å; A137-G140 PolarHBondContact O-N 3.38Å
141	N	54.1	Low	59.2	Low	41 Å²	41	64 Å²	64	22%	0.219	36%	0.355	C	S	.	.	H	α-helix	trans	-73.3	-42.5	-176	-72.2	21.5	0	0	0	112.4	A137 K143 I144 T145	A137-N141 VanDerWaalsContact O-CB 3.3Å; A137-N141 WeakPolarHBondContact O-CB 2.98Å; A137-N141 PolarHBondContact O-N 2.89Å; A137-N141 PolarHBondContact O-OD1 3.3Å; N141-K143 PolarHBondContact O-N 3.12Å; N141-I144 PolarHBondContact O-N 3.49Å; N141-T145 PolarHBondContact O-N 3.05Å; N141-T145 VanDerWaalsContact O-N 3.08Å; N141-T145 PolarHBondContact O-OG1 2.88Å
142	S	56.3	Low	61.1	Low	31 Å²	31	60.3 Å²	60.3	22%	0.217	33%	0.332	C	S	.	.	H	α-helix	trans	-60.2	-31.8	178.3	68.7	0	0	0	0	113.1	R138 S139 T146	R138-S142 PolarHBondContact O-N 3.1Å; S139-S142 PolarHBondContact O-OG 3.39Å; S142-T146 WeakPolarHBondContact O-CB 3.41Å; S142-T146 PolarHBondContact O-N 3.1Å; S142-T146 PolarHBondContact O-OG1 2.97Å
143	K	63.8	Low	63.1	Low	41 Å²	41	51.8 Å²	51.8	18%	0.178	29%	0.287	C	S	.	.	H	α-helix	trans	-72.2	-39.4	-178.7	-65.5	165.4	-166	-174	0	112.6	S139 N141 T147 A198 L200	S139-K143 WeakPolarHBondContact O-CD 3.12Å; S139-K143 WeakPolarHBondContact O-CE 3.33Å; S139-K143 WeakPolarHBondContact O-CG 3.44Å; S139-K143 WeakPolarHBondContact OG-CE 3.29Å; S139-K143 PolarHBondContact OG-NZ 3.33Å; N141-K143 PolarHBondContact O-N 3.12Å; K143-T147 PolarHBondContact O-N 3.07Å; K143-T147 PolarHBondContact O-OG1 2.76Å; K143-A198 HydrophobicContact CD-CB 4.13Å; K143-A198 HydrophobicContact CG-CB 4.14Å; K143-A198 PolarHBondContact NZ-O 3.08Å; K143-L200 HydrophobicContact CB-CD1 4.37Å; K143-L200 HydrophobicContact CD-CD1 3.75Å; K143-L200 HydrophobicContact CG-CD1 4.17Å
144	I	63.9	Low	65	Low	92 Å²	92	47.4 Å²	47.4	47%	0.472	26%	0.263	S	S	.	.	H	α-helix	trans	-72.3	-42.6	177	-63.2	170.5	0	0	0	109.5	N141 T146 T147 L148	N141-I144 PolarHBondContact O-N 3.49Å; I144-T146 PolarHBondContact O-N 3.46Å; I144-T147 PolarHBondContact O-N 3.47Å; I144-L148 WeakPolarHBondContact O-CB 3.47Å; I144-L148 PolarHBondContact O-N 2.95Å
145	T	69.3	Low	66.9	Low	7 Å²	7	44 Å²	44	4%	0.043	24%	0.244	C	C	.	.	H	α-helix	trans	-64.9	-39.1	-179.9	-51.5	0	0	0	0	112.9	D121 N141 T147 L148 G149	D121-T145 HydrophobicContact CB-CG2 3.65Å; D121-T145 WeakPolarHBondContact OD1-CG2 3.25Å; N141-T145 PolarHBondContact O-N 3.05Å; N141-T145 VanDerWaalsContact O-N 3.08Å; N141-T145 PolarHBondContact O-OG1 2.88Å; T145-T147 VanDerWaalsContact C-N 3.3Å; T145-T147 PolarHBondContact O-N 2.93Å; T145-L148 PolarHBondContact O-N 3.29Å; T145-G149 PolarHBondContact O-N 3.48Å
146	T	67.6	Low	69	Low	2 Å²	2	36.5 Å²	36.5	1%	0.012	21%	0.21	C	C	.	.	H	α-helix	trans	-59.2	-42.6	174.1	-58.1	0	0	0	0	111.4	S142 I144 L150 F194 V255 H259	S142-T146 WeakPolarHBondContact O-CB 3.41Å; S142-T146 PolarHBondContact O-N 3.1Å; S142-T146 PolarHBondContact O-OG1 2.97Å; I144-T146 PolarHBondContact O-N 3.46Å; T146-L150 HydrophobicContact CG2-CD1 4.14Å; T146-L150 WeakPolarHBondContact O-CG 3.4Å; T146-L150 PolarHBondContact O-N 3.33Å; T146-L150 VanDerWaalsContact O-N 3.1Å; T146-F194 HydrophobicContact CG2-CD1 4.03Å; T146-F194 HydrophobicContact CG2-CE1 3.75Å; T146-F194 HydrophobicContact CG2-CZ 4.38Å; T146-V255 HydrophobicContact CG2-CG1 4.2Å; T146-H259 PolarHBondContact OG1-CD2 2.86Å
147	T	72.6	Confident	71.2	Confident	8 Å²	8	33.5 Å²	33.5	5%	0.049	19%	0.185	C	C	.	.	H	α-helix	trans	-71.3	-42.6	177.4	-53.5	0	0	0	0	111.7	K143 I144 T145 G149 L150 V151 H208	K143-T147 PolarHBondContact O-N 3.07Å; K143-T147 PolarHBondContact O-OG1 2.76Å; I144-T147 PolarHBondContact O-N 3.47Å; T145-T147 VanDerWaalsContact C-N 3.3Å; T145-T147 PolarHBondContact O-N 2.93Å; T147-G149 PolarHBondContact O-N 3.36Å; T147-L150 PolarHBondContact O-N 3.48Å; T147-L150 VanDerWaalsContact O-N 3.16Å; T147-V151 HydrophobicContact CG2-CG2 4.1Å; T147-V151 WeakPolarHBondContact O-CB 3.28Å; T147-V151 VanDerWaalsContact O-CG2 3.26Å; T147-V151 WeakPolarHBondContact O-CG2 3.12Å; T147-V151 PolarHBondContact O-N 3.4Å; T147-H208 HydrophobicContact CG2-CB 3.82Å; T147-H208 PolarHBondContact OG1-CD2 3.18Å
148	L	79.2	Confident	73.5	Confident	76 Å²	76	32.1 Å²	32.1	40%	0.398	17%	0.174	S	C	.	.	H	α-helix	trans	-55.9	-43.2	176.5	-179.2	62.6	0	0	0	110.5	V120 I144 T145 V151 V152	V120-L148 HydrophobicContact CG1-CD2 3.68Å; V120-L148 HydrophobicContact CG1-CG 3.93Å; I144-L148 WeakPolarHBondContact O-CB 3.47Å; I144-L148 PolarHBondContact O-N 2.95Å; T145-L148 PolarHBondContact O-N 3.29Å; L148-V151 PolarHBondContact O-N 2.96Å; L148-V152 WeakPolarHBondContact O-CG2 3.31Å; L148-V152 PolarHBondContact O-N 3.37Å
149	G	77.6	Confident	75.6	Confident	0 Å²	0	24.7 Å²	24.7	0%	0	15%	0.151	C	C	.	.	H	α-helix	trans	-64.2	-41.3	176.7	0	0	0	0	0	114.6	M117 T145 T147 V151 V152 H153	M117-G149 WeakPolarHBondContact SD-CA 3.36Å; T145-G149 PolarHBondContact O-N 3.48Å; T147-G149 PolarHBondContact O-N 3.36Å; G149-V151 VanDerWaalsContact C-N 3.31Å; G149-V151 PolarHBondContact O-N 3.07Å; G149-V152 PolarHBondContact O-N 3.49Å; G149-H153 WeakPolarHBondContact O-CB 3.41Å; G149-H153 PolarHBondContact O-N 2.86Å
150	L	77.8	Confident	77.7	Confident	1 Å²	1	22.5 Å²	22.5	1%	0.005	14%	0.136	C	C	.	.	H	α-helix	trans	-69.7	-30	175.7	-71.6	168.2	0	0	0	112.7	T146 T147 A154 L191 F212 F252 V255	T146-L150 HydrophobicContact CG2-CD1 4.14Å; T146-L150 WeakPolarHBondContact O-CG 3.4Å; T146-L150 PolarHBondContact O-N 3.33Å; T146-L150 VanDerWaalsContact O-N 3.1Å; T147-L150 PolarHBondContact O-N 3.48Å; T147-L150 VanDerWaalsContact O-N 3.16Å; L150-A154 WeakPolarHBondContact O-CB 3.29Å; L150-A154 PolarHBondContact O-N 3.01Å; L150-L191 HydrophobicContact CD1-CB 3.89Å; L150-L191 HydrophobicContact CD1-CD1 3.32Å; L150-L191 HydrophobicContact CD1-CD2 4.32Å; L150-L191 HydrophobicContact CD1-CG 3.99Å; L150-F212 HydrophobicContact CB-CD2 3.86Å; L150-F212 HydrophobicContact CB-CE2 3.97Å; L150-F212 VanDerWaalsContact O-CD2 3.3Å; L150-F212 WeakPolarHBondContact O-CD2 3.46Å; L150-F212 VanDerWaalsContact O-CE2 3.29Å; L150-F212 WeakPolarHBondContact O-CE2 3.3Å; L150-F252 HydrophobicContact CD2-CD2 3.8Å; L150-F252 HydrophobicContact CD2-CE2 3.54Å; L150-V255 HydrophobicContact CD1-CG1 4.29Å; L150-V255 HydrophobicContact CD2-CG1 3.99Å; L150-V255 HydrophobicContact CG-CG1 3.99Å
151	V	87.6	Confident	79.7	Confident	30 Å²	30	21 Å²	21	18%	0.182	12%	0.121	C	C	.	.	H	α-helix	trans	-69.2	-44	173.2	168.9	0	0	0	0	110.9	T147 L148 G149 H153 A154 A155 V211 A215	T147-V151 HydrophobicContact CG2-CG2 4.1Å; T147-V151 WeakPolarHBondContact O-CB 3.28Å; T147-V151 VanDerWaalsContact O-CG2 3.26Å; T147-V151 WeakPolarHBondContact O-CG2 3.12Å; T147-V151 PolarHBondContact O-N 3.4Å; L148-V151 PolarHBondContact O-N 2.96Å; G149-V151 VanDerWaalsContact C-N 3.31Å; G149-V151 PolarHBondContact O-N 3.07Å; V151-H153 VanDerWaalsContact C-N 3.35Å; V151-A154 PolarHBondContact O-N 3.45Å; V151-A155 WeakPolarHBondContact O-CB 3.25Å; V151-A155 PolarHBondContact O-N 3.28Å; V151-V211 HydrophobicContact CG1-CG1 4.25Å; V151-V211 HydrophobicContact CG2-CB 4.46Å; V151-V211 HydrophobicContact CG2-CG1 3.7Å; V151-A215 HydrophobicContact CG1-CB 4.07Å
152	V	86.3	Confident	81.4	Confident	31 Å²	31	19.1 Å²	19.1	19%	0.188	11%	0.11	C	C	.	.	H	α-helix	trans	-59	-46.5	173	162.4	0	0	0	0	111.1	F116 M117 L148 G149 A155 A156 T251	F116-V152 HydrophobicContact CD1-CG1 3.93Å; F116-V152 HydrophobicContact CE1-CG1 3.47Å; F116-V152 VanDerWaalsContact CE1-CG1 3.47Å; F116-V152 HydrophobicContact CE1-CG2 4.45Å; M117-V152 HydrophobicContact SD-CB 3.95Å; M117-V152 HydrophobicContact SD-CG1 3.77Å; M117-V152 HydrophobicContact SD-CG2 4.49Å; L148-V152 WeakPolarHBondContact O-CG2 3.31Å; L148-V152 PolarHBondContact O-N 3.37Å; G149-V152 PolarHBondContact O-N 3.49Å; V152-A155 WeakPolarHBondContact O-CB 3.28Å; V152-A155 PolarHBondContact O-N 3.34Å; V152-A156 PolarHBondContact O-N 3.34Å; V152-T251 HydrophobicContact CG1-CG2 4.44Å
153	H	88	Confident	82.9	Confident	0 Å²	0	17.9 Å²	17.9	0%	0	10%	0.102	C	C	.	.	H	α-helix	trans	-56.6	-52.6	174.9	164.5	58.4	0	0	0	111.3	G149 V151 A155 A156 D157 S248 T251 F252	G149-H153 WeakPolarHBondContact O-CB 3.41Å; G149-H153 PolarHBondContact O-N 2.86Å; V151-H153 VanDerWaalsContact C-N 3.35Å; H153-A155 PolarHBondContact O-N 2.82Å; H153-A156 WeakPolarHBondContact O-CA 3.43Å; H153-A156 WeakPolarHBondContact O-CB 3.29Å; H153-A156 PolarHBondContact O-N 3.47Å; H153-D157 IonicContact CE1-OD1 2.67Å; H153-D157 IonicContact CE1-OD2 3.53Å; H153-D157 IonicContact NE2-OD2 3.75Å; H153-D157 PolarHBondContact O-N 3.15Å; H153-D157 VanDerWaalsContact O-N 3.12Å; H153-S248 PolarHBondContact CE1-OG 3.01Å; H153-S248 PolarHBondContact ND1-O 3.32Å; H153-S248 PolarHBondContact ND1-OG 3.03Å; H153-S248 PolarHBondContact O-OG 3.36Å; H153-T251 WeakPolarHBondContact CA-OG1 3.33Å; H153-T251 WeakPolarHBondContact CB-OG1 3.49Å; H153-T251 PolarHBondContact ND1-OG1 3.43Å; H153-F252 AromaticContact CD2-CD2 3.44Å; H153-F252 VanDerWaalsContact CD2-CD2 3.44Å; H153-F252 WeakPolarHBondContact CD2-CD2 3.36Å; H153-F252 AromaticContact CD2-CE2 3.8Å; H153-F252 AromaticContact CE1-CD2 3.87Å; H153-F252 AromaticContact CE1-CG 3.77Å; H153-F252 AromaticContact CG-CD2 3.83Å; H153-F252 AromaticContact NE2-CD2 3.45Å; H153-F252 WeakPolarHBondContact NE2-CD2 3.3Å; H153-F252 AromaticContact NE2-CE2 3.71Å; H153-F252 AromaticContact NE2-CG 3.77Å
154	A	91.4	Very high	83.9	Confident	0 Å²	0	15.9 Å²	15.9	0%	0	9%	0.093	C	C	.	.	H	α-helix	trans	-60.6	-34.4	177.1	0	0	0	0	0	112.5	L150 V151 A156 D157 G158 F212 A215 A216	L150-A154 WeakPolarHBondContact O-CB 3.29Å; L150-A154 PolarHBondContact O-N 3.01Å; V151-A154 PolarHBondContact O-N 3.45Å; A154-A156 VanDerWaalsContact C-N 3.35Å; A154-D157 PolarHBondContact O-N 3.01Å; A154-G158 PolarHBondContact O-N 3.4Å; A154-G158 VanDerWaalsContact O-N 3.09Å; A154-F212 HydrophobicContact CB-CD2 3.95Å; A154-F212 HydrophobicContact CB-CE2 3.82Å; A154-F212 HydrophobicContact CB-CZ 4.49Å; A154-A215 HydrophobicContact CB-CB 3.76Å; A154-A216 HydrophobicContact CB-CB 4.49Å; A154-A216 WeakPolarHBondContact O-CA 3.3Å; A154-A216 WeakPolarHBondContact O-CB 3.3Å; A154-A216 PolarHBondContact O-N 3.14Å
155	A	92.3	Very high	85	Confident	24 Å²	24	11.7 Å²	11.7	20%	0.198	7%	0.072	C	C	.	.	H	α-helix	trans	-63.4	-40.2	173.7	0	0	0	0	0	111.8	V151 V152 H153 G158 V159 M219	V151-A155 WeakPolarHBondContact O-CB 3.25Å; V151-A155 PolarHBondContact O-N 3.28Å; V152-A155 WeakPolarHBondContact O-CB 3.28Å; V152-A155 PolarHBondContact O-N 3.34Å; H153-A155 PolarHBondContact O-N 2.82Å; A155-G158 WeakPolarHBondContact O-CA 3.4Å; A155-G158 PolarHBondContact O-N 2.88Å; A155-G158 VanDerWaalsContact O-N 3.16Å; A155-V159 WeakPolarHBondContact O-CG2 3.43Å; A155-V159 PolarHBondContact O-N 2.98Å; A155-M219 HydrophobicContact CB-CB 4.5Å; A155-M219 HydrophobicContact CB-CG 3.77Å; A155-M219 WeakPolarHBondContact O-CB 3.43Å
156	A	90.3	Very high	85.6	Confident	10 Å²	10	13.4 Å²	13.4	8%	0.083	8%	0.084	C	C	.	.	H	α-helix	trans	-63.2	-39.4	175	0	0	0	0	0	112.3	V152 H153 A154 G158 V159 A160 F247	V152-A156 PolarHBondContact O-N 3.34Å; H153-A156 WeakPolarHBondContact O-CA 3.43Å; H153-A156 WeakPolarHBondContact O-CB 3.29Å; H153-A156 PolarHBondContact O-N 3.47Å; A154-A156 VanDerWaalsContact C-N 3.35Å; A156-G158 VanDerWaalsContact C-N 3.28Å; A156-G158 PolarHBondContact O-N 3.49Å; A156-V159 WeakPolarHBondContact O-CB 3.48Å; A156-V159 PolarHBondContact O-N 3.48Å; A156-A160 PolarHBondContact O-N 2.91Å; A156-F247 HydrophobicContact CB-CD1 4.04Å; A156-F247 HydrophobicContact CB-CE1 4.42Å
157	D	90.4	Very high	86	Confident	1 Å²	1	15.7 Å²	15.7	1%	0.005	10%	0.099	C	C	.	.	H	α-helix	trans	-60.3	-40.7	172.2	-53.9	-22.8	0	0	0	111.4	H153 A154 A160 L161 I180 H183 K184 A216 S248	H153-D157 IonicContact CE1-OD1 2.67Å; H153-D157 IonicContact CE1-OD2 3.53Å; H153-D157 IonicContact NE2-OD2 3.75Å; H153-D157 PolarHBondContact O-N 3.15Å; H153-D157 VanDerWaalsContact O-N 3.12Å; A154-D157 PolarHBondContact O-N 3.01Å; D157-A160 PolarHBondContact O-N 2.98Å; D157-L161 PolarHBondContact O-N 3.37Å; D157-I180 HydrophobicContact CB-CD1 4.26Å; D157-I180 HydrophobicContact CB-CG1 4.36Å; D157-I180 HydrophobicContact CB-CG2 4.08Å; D157-I180 WeakPolarHBondContact O-CD1 3.25Å; D157-H183 IonicContact OD1-NE2 3.14Å; D157-H183 IonicContact OD2-NE2 3.28Å; D157-K184 IonicContact OD2-NZ 2.65Å; D157-A216 HydrophobicContact CB-CB 4.36Å; D157-S248 WeakPolarHBondContact OD1-CB 3.15Å; D157-S248 PolarHBondContact OD1-OG 3.47Å
158	G	92.6	Very high	85.8	Confident	0 Å²	0	19.6 Å²	19.6	0%	0	13%	0.126	C	C	.	.	H	α-helix	trans	-59.5	-45.7	174.7	0	0	0	0	0	111.9	A154 A155 A156 A160 L161 G162 A216 S220	A154-G158 PolarHBondContact O-N 3.4Å; A154-G158 VanDerWaalsContact O-N 3.09Å; A155-G158 WeakPolarHBondContact O-CA 3.4Å; A155-G158 PolarHBondContact O-N 2.88Å; A155-G158 VanDerWaalsContact O-N 3.16Å; A156-G158 VanDerWaalsContact C-N 3.28Å; A156-G158 PolarHBondContact O-N 3.49Å; G158-A160 VanDerWaalsContact C-N 3.34Å; G158-A160 PolarHBondContact O-N 3.43Å; G158-L161 PolarHBondContact O-N 3.49Å; G158-G162 PolarHBondContact O-N 3.48Å; G158-A216 WeakPolarHBondContact CA-O 3.28Å; G158-S220 WeakPolarHBondContact O-CA 3.04Å; G158-S220 WeakPolarHBondContact O-CB 3.35Å; G158-S220 PolarHBondContact O-N 2.66Å
159	V	91.8	Very high	85.7	Confident	47 Å²	47	19.3 Å²	19.3	29%	0.285	12%	0.123	S	C	.	.	H	α-helix	trans	-58.4	-46.1	175.1	174.6	0	0	0	0	111.2	A155 A156 G162 A163 M219 T223 A244	A155-V159 WeakPolarHBondContact O-CG2 3.43Å; A155-V159 PolarHBondContact O-N 2.98Å; A156-V159 WeakPolarHBondContact O-CB 3.48Å; A156-V159 PolarHBondContact O-N 3.48Å; V159-G162 PolarHBondContact O-N 3.35Å; V159-A163 VanDerWaalsContact O-CB 3.31Å; V159-A163 WeakPolarHBondContact O-CB 3.28Å; V159-A163 PolarHBondContact O-N 3.19Å; V159-M219 HydrophobicContact CG2-CE 3.58Å; V159-T223 HydrophobicContact CG1-CG2 4.37Å; V159-A244 HydrophobicContact CG1-CB 4.13Å
160	A	89.4	Confident	85.8	Confident	0 Å²	0	22.6 Å²	22.6	0%	0	14%	0.143	C	C	.	.	H	α-helix	trans	-59.3	-49.9	177.9	0	0	0	0	0	112.3	A156 D157 G158 G162 A163 A164 A244 M245	A156-A160 PolarHBondContact O-N 2.91Å; D157-A160 PolarHBondContact O-N 2.98Å; G158-A160 VanDerWaalsContact C-N 3.34Å; G158-A160 PolarHBondContact O-N 3.43Å; A160-G162 PolarHBondContact O-N 3.26Å; A160-A163 PolarHBondContact O-N 2.93Å; A160-A164 WeakPolarHBondContact O-CB 3.04Å; A160-A164 PolarHBondContact O-N 2.86Å; A160-A244 HydrophobicContact CB-CB 3.96Å; A160-M245 HydrophobicContact CB-CG 3.52Å
161	L	90.8	Very high	85.9	Confident	0 Å²	0	26.7 Å²	26.7	0%	0	17%	0.172	C	C	.	.	H	α-helix	trans	-65.1	-39.9	178.6	-178.4	62.7	0	0	0	112.4	M14 D157 G158 A164 A165 Q173 V176 F177 I180	M14-L161 HydrophobicContact CE-CD2 3.2Å; D157-L161 PolarHBondContact O-N 3.37Å; G158-L161 PolarHBondContact O-N 3.49Å; L161-A164 PolarHBondContact O-N 3.35Å; L161-A165 VanDerWaalsContact O-CB 3.3Å; L161-A165 WeakPolarHBondContact O-CB 3.17Å; L161-A165 PolarHBondContact O-N 3.46Å; L161-Q173 HydrophobicContact CD1-CG 4.17Å; L161-V176 HydrophobicContact CD1-CG1 4.37Å; L161-F177 HydrophobicContact CD1-CB 3.93Å; L161-F177 HydrophobicContact CD2-CD2 4.12Å; L161-I180 HydrophobicContact CB-CD1 3.88Å
162	G	90.4	Very high	85.5	Confident	0 Å²	0	25.9 Å²	25.9	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-66	-37.5	178.2	0	0	0	0	0	112.7	G158 V159 A160 S166 S220	G158-G162 PolarHBondContact O-N 3.48Å; V159-G162 PolarHBondContact O-N 3.35Å; A160-G162 PolarHBondContact O-N 3.26Å; G162-S166 PolarHBondContact O-N 3.21Å; G162-S220 WeakPolarHBondContact CA-O 3.12Å; G162-S220 PolarHBondContact N-OG 3.2Å
163	A	87.4	Confident	85.4	Confident	5 Å²	5	24.5 Å²	24.5	4%	0.041	16%	0.158	C	C	.	.	H	α-helix	trans	-65.4	-48.7	172.8	0	0	0	0	0	110.9	V159 A160 A165 S166 T167 T223 L227 A240	V159-A163 VanDerWaalsContact O-CB 3.31Å; V159-A163 WeakPolarHBondContact O-CB 3.28Å; V159-A163 PolarHBondContact O-N 3.19Å; A160-A163 PolarHBondContact O-N 2.93Å; A163-A165 VanDerWaalsContact C-N 3.32Å; A163-A165 PolarHBondContact O-N 3.48Å; A163-S166 WeakPolarHBondContact O-CB 3.02Å; A163-S166 PolarHBondContact O-N 3.31Å; A163-S166 PolarHBondContact O-OG 2.97Å; A163-T167 PolarHBondContact O-N 2.61Å; A163-T223 HydrophobicContact CB-CG2 4.42Å; A163-L227 HydrophobicContact CB-CD1 4.31Å; A163-A240 HydrophobicContact CB-CB 4.39Å
164	A	85.6	Confident	85.4	Confident	0 Å²	0	28.4 Å²	28.4	0%	0	18%	0.179	C	C	.	.	H	α-helix	trans	-57.4	-43.4	176.2	0	0	0	0	0	112.2	A160 L161 S166 T167 V172 V176 T241	A160-A164 WeakPolarHBondContact O-CB 3.04Å; A160-A164 PolarHBondContact O-N 2.86Å; L161-A164 PolarHBondContact O-N 3.35Å; A164-S166 PolarHBondContact O-N 2.93Å; A164-T167 PolarHBondContact O-N 3.31Å; A164-T167 VanDerWaalsContact O-N 3.15Å; A164-T167 VanDerWaalsContact O-O 3.13Å; A164-T167 PolarHBondContact O-OG1 3.13Å; A164-V172 HydrophobicContact CB-CG1 4.5Å; A164-V176 HydrophobicContact CB-CB 4.32Å; A164-V176 HydrophobicContact CB-CG1 4.38Å; A164-V176 HydrophobicContact CB-CG2 4.21Å; A164-T241 HydrophobicContact CB-CG2 4.02Å; A164-T241 PolarHBondContact N-OG1 3.44Å
165	A	87.1	Confident	85	Confident	3 Å²	3	32.4 Å²	32.4	3%	0.025	20%	0.199	C	C	.	.	H	α-helix	trans	-66.5	-19	177.7	0	0	0	0	0	114.2	I7 L161 A163 Q173 Y224	I7-A165 HydrophobicContact CB-CB 4.31Å; I7-A165 HydrophobicContact CD1-CB 3.72Å; I7-A165 HydrophobicContact CG1-CB 4.16Å; L161-A165 VanDerWaalsContact O-CB 3.3Å; L161-A165 WeakPolarHBondContact O-CB 3.17Å; L161-A165 PolarHBondContact O-N 3.46Å; A163-A165 VanDerWaalsContact C-N 3.32Å; A163-A165 PolarHBondContact O-N 3.48Å; A165-Q173 HydrophobicContact CB-CG 4.09Å; A165-Q173 VanDerWaalsContact CB-NE2 3.33Å; A165-Y224 HydrophobicContact CB-CD2 3.93Å; A165-Y224 HydrophobicContact CB-CE2 4.5Å; A165-Y224 WeakPolarHBondContact O-CE2 3.4Å
166	S	82.3	Confident	84.5	Confident	43 Å²	43	31.5 Å²	31.5	30%	0.301	19%	0.191	S	C	.	.	H	α-helix	trans	-82.9	-19.8	176	77.1	0	0	0	0	112.9	G162 A163 A164 L227	G162-S166 PolarHBondContact O-N 3.21Å; A163-S166 WeakPolarHBondContact O-CB 3.02Å; A163-S166 PolarHBondContact O-N 3.31Å; A163-S166 PolarHBondContact O-OG 2.97Å; A164-S166 PolarHBondContact O-N 2.93Å; S166-L227 WeakPolarHBondContact OG-CD1 3.3Å
167	T	74.9	Confident	84.5	Confident	51 Å²	51	32.3 Å²	32.3	31%	0.313	19%	0.193	S	C	.	.	S	Bend	trans	-78.5	127.4	166	77.9	0	0	0	0	106.6	A163 A164 Q169	A163-T167 PolarHBondContact O-N 2.61Å; A164-T167 PolarHBondContact O-N 3.31Å; A164-T167 VanDerWaalsContact O-N 3.15Å; A164-T167 VanDerWaalsContact O-O 3.13Å; A164-T167 PolarHBondContact O-OG1 3.13Å; T167-Q169 PolarHBondContact O-N 2.77Å
168	S	68.6	Low	84.4	Confident	90 Å²	90	35 Å²	35	63%	0.629	21%	0.209	S	C	*	.	S	Bend	trans	-68.6	23.8	-176.3	-57.4	0	0	0	0	113.9
169	Q	77.3	Confident	83.9	Confident	70 Å²	70	35.3 Å²	35.3	33%	0.327	21%	0.212	S	C	.	.			trans	-102.3	93.9	179.3	-62.1	-167.2	5.2	0	0	110.5	E68 T167 S171 V172 Q173	E68-Q169 PolarHBondContact OE1-NE2 3.42Å; E68-Q169 PolarHBondContact OE1-OE1 3.27Å; E68-Q169 PolarHBondContact OE2-NE2 3.3Å; E68-Q169 PolarHBondContact OE2-OE1 3.01Å; T167-Q169 PolarHBondContact O-N 2.77Å; Q169-S171 PolarHBondContact O-N 3.13Å; Q169-V172 HydrophobicContact CB-CB 4.31Å; Q169-V172 HydrophobicContact CB-CG2 4.23Å; Q169-V172 PolarHBondContact O-N 3.4Å; Q169-Q173 PolarHBondContact O-N 2.98Å
170	T	80.6	Confident	83.7	Confident	68 Å²	68	33 Å²	33	42%	0.417	20%	0.198	S	C	.	.	H	α-helix	trans	-61.1	-28.4	178.9	-43.5	0	0	0	0	112.7	Q173 L174	T170-Q173 PolarHBondContact O-N 3.28Å; T170-L174 HydrophobicContact CG2-CD1 4.23Å; T170-L174 HydrophobicContact CG2-CG 4.37Å; T170-L174 WeakPolarHBondContact O-CB 3.38Å; T170-L174 VanDerWaalsContact O-CG 3.29Å; T170-L174 WeakPolarHBondContact O-CG 3.37Å; T170-L174 PolarHBondContact O-N 3.41Å
171	S	79.9	Confident	83.6	Confident	87 Å²	87	34.4 Å²	34.4	61%	0.608	21%	0.205	S	C	*	.	H	α-helix	trans	-63.1	-50.7	177.5	-56.4	0	0	0	0	111.9	Q169 Q173 L174 I175	Q169-S171 PolarHBondContact O-N 3.13Å; S171-Q173 VanDerWaalsContact C-N 3.33Å; S171-Q173 PolarHBondContact O-N 3.09Å; S171-L174 PolarHBondContact O-N 3.16Å; S171-I175 VanDerWaalsContact O-CG1 3.3Å; S171-I175 WeakPolarHBondContact O-CG1 3.45Å; S171-I175 PolarHBondContact O-N 2.84Å
172	V	77.6	Confident	83.3	Confident	13 Å²	13	36.2 Å²	36.2	8%	0.079	21%	0.214	C	C	.	.	H	α-helix	trans	-62.8	-42.6	177.6	176.3	0	0	0	0	110.4	A164 Q169 L174 I175 V176	A164-V172 HydrophobicContact CB-CG1 4.5Å; Q169-V172 HydrophobicContact CB-CB 4.31Å; Q169-V172 HydrophobicContact CB-CG2 4.23Å; Q169-V172 PolarHBondContact O-N 3.4Å; V172-L174 VanDerWaalsContact C-N 3.32Å; V172-L174 PolarHBondContact O-N 3.2Å; V172-I175 PolarHBondContact O-N 3.26Å; V172-V176 HydrophobicContact CG1-CG2 4.22Å; V172-V176 WeakPolarHBondContact O-CB 3.39Å; V172-V176 VanDerWaalsContact O-CG2 3.25Å; V172-V176 WeakPolarHBondContact O-CG2 3.34Å; V172-V176 PolarHBondContact O-N 3.36Å
173	Q	85.4	Confident	83	Confident	3 Å²	3	36.3 Å²	36.3	1%	0.014	22%	0.215	C	C	.	.	H	α-helix	trans	-55.3	-45	174.4	-175.1	-172.4	19	0	0	112.4	S6 L10 L161 A165 Q169 T170 S171 F177	S6-Q173 PolarHBondContact OG-OE1 2.9Å; L10-Q173 HydrophobicContact CD1-CG 3.84Å; L161-Q173 HydrophobicContact CD1-CG 4.17Å; A165-Q173 HydrophobicContact CB-CG 4.09Å; A165-Q173 VanDerWaalsContact CB-NE2 3.33Å; Q169-Q173 PolarHBondContact O-N 2.98Å; T170-Q173 PolarHBondContact O-N 3.28Å; S171-Q173 VanDerWaalsContact C-N 3.33Å; S171-Q173 PolarHBondContact O-N 3.09Å; Q173-F177 VanDerWaalsContact O-CB 3.25Å; Q173-F177 WeakPolarHBondContact O-CB 3.45Å; Q173-F177 PolarHBondContact O-N 3.12Å
174	L	86.6	Confident	83.1	Confident	81 Å²	81	36.1 Å²	36.1	42%	0.424	21%	0.213	S	C	.	.	H	α-helix	trans	-71.8	-39.7	-179.8	-72.2	175.4	0	0	0	112.6	L10 T170 S171 V172 F177 V178	L10-L174 HydrophobicContact CD1-CD2 4.4Å; L10-L174 HydrophobicContact CD2-CD2 4.17Å; T170-L174 HydrophobicContact CG2-CD1 4.23Å; T170-L174 HydrophobicContact CG2-CG 4.37Å; T170-L174 WeakPolarHBondContact O-CB 3.38Å; T170-L174 VanDerWaalsContact O-CG 3.29Å; T170-L174 WeakPolarHBondContact O-CG 3.37Å; T170-L174 PolarHBondContact O-N 3.41Å; S171-L174 PolarHBondContact O-N 3.16Å; V172-L174 VanDerWaalsContact C-N 3.32Å; V172-L174 PolarHBondContact O-N 3.2Å; L174-F177 PolarHBondContact O-N 3Å; L174-V178 WeakPolarHBondContact O-CG2 3.46Å; L174-V178 PolarHBondContact O-N 3.48Å
175	I	83.1	Confident	83.1	Confident	84 Å²	84	37.7 Å²	37.7	43%	0.431	23%	0.226	S	C	.	.	H	α-helix	trans	-60.2	-51.1	175.4	-69.1	164.9	0	0	0	109.8	S171 V172 F177 V178 A179	S171-I175 VanDerWaalsContact O-CG1 3.3Å; S171-I175 WeakPolarHBondContact O-CG1 3.45Å; S171-I175 PolarHBondContact O-N 2.84Å; V172-I175 PolarHBondContact O-N 3.26Å; I175-F177 VanDerWaalsContact C-N 3.32Å; I175-F177 PolarHBondContact O-N 3.37Å; I175-V178 PolarHBondContact O-N 3.5Å; I175-A179 WeakPolarHBondContact O-CB 3.42Å; I175-A179 PolarHBondContact O-N 2.92Å
176	V	83.3	Confident	83	Confident	5 Å²	5	38.4 Å²	38.4	3%	0.03	23%	0.23	C	C	.	.	H	α-helix	trans	-60.9	-41.7	177.5	173.1	0	0	0	0	111	L161 A164 V172 A179 I180 T241 M245	L161-V176 HydrophobicContact CD1-CG1 4.37Å; A164-V176 HydrophobicContact CB-CB 4.32Å; A164-V176 HydrophobicContact CB-CG1 4.38Å; A164-V176 HydrophobicContact CB-CG2 4.21Å; V172-V176 HydrophobicContact CG1-CG2 4.22Å; V172-V176 WeakPolarHBondContact O-CB 3.39Å; V172-V176 VanDerWaalsContact O-CG2 3.25Å; V172-V176 WeakPolarHBondContact O-CG2 3.34Å; V172-V176 PolarHBondContact O-N 3.36Å; V176-A179 PolarHBondContact O-N 3.27Å; V176-I180 HydrophobicContact CG1-CD1 3.67Å; V176-I180 HydrophobicContact CG1-CG1 4.39Å; V176-I180 WeakPolarHBondContact O-CB 3.26Å; V176-I180 VanDerWaalsContact O-CG1 3.23Å; V176-I180 WeakPolarHBondContact O-CG1 3.43Å; V176-I180 PolarHBondContact O-N 3.38Å; V176-T241 HydrophobicContact CG1-CG2 4.35Å; V176-T241 HydrophobicContact CG2-CG2 3.85Å; V176-M245 HydrophobicContact CG1-SD 4.1Å; V176-M245 HydrophobicContact CG2-CE 4.25Å
177	F	89.9	Confident	83.2	Confident	28 Å²	28	36.3 Å²	36.3	12%	0.123	22%	0.216	C	C	.	.	H	α-helix	trans	-61	-47.2	176.1	171	-100.1	0	0	0	112.8	L10 A13 M14 L161 Q173 L174 I175 I180 M181	L10-F177 HydrophobicContact CB-CD2 3.84Å; L10-F177 HydrophobicContact CB-CE2 3.94Å; L10-F177 HydrophobicContact CB-CG 4.47Å; L10-F177 HydrophobicContact CD1-CB 4.29Å; L10-F177 HydrophobicContact CD1-CD2 4.42Å; L10-F177 HydrophobicContact CD1-CG 4.31Å; L10-F177 HydrophobicContact CD2-CD1 3.8Å; L10-F177 HydrophobicContact CD2-CD2 3.94Å; L10-F177 HydrophobicContact CD2-CE1 3.87Å; L10-F177 HydrophobicContact CD2-CE2 4.01Å; L10-F177 HydrophobicContact CD2-CG 3.82Å; L10-F177 HydrophobicContact CD2-CZ 3.98Å; L10-F177 HydrophobicContact CG-CD2 4.28Å; L10-F177 HydrophobicContact CG-CG 4.42Å; L10-F177 VanDerWaalsContact O-CE2 3.31Å; L10-F177 WeakPolarHBondContact O-CE2 3.33Å; A13-F177 HydrophobicContact CB-CZ 4.01Å; M14-F177 HydrophobicContact CB-CE2 4.14Å; M14-F177 HydrophobicContact CE-CD2 4.16Å; M14-F177 HydrophobicContact CE-CE2 4.36Å; L161-F177 HydrophobicContact CD1-CB 3.93Å; L161-F177 HydrophobicContact CD2-CD2 4.12Å; Q173-F177 VanDerWaalsContact O-CB 3.25Å; Q173-F177 WeakPolarHBondContact O-CB 3.45Å; Q173-F177 PolarHBondContact O-N 3.12Å; L174-F177 PolarHBondContact O-N 3Å; I175-F177 VanDerWaalsContact C-N 3.32Å; I175-F177 PolarHBondContact O-N 3.37Å; F177-I180 PolarHBondContact O-N 3.32Å; F177-M181 HydrophobicContact CD1-CG 4.41Å; F177-M181 HydrophobicContact CD2-CG 4.19Å; F177-M181 HydrophobicContact CE1-CG 3.97Å; F177-M181 HydrophobicContact CE2-CG 3.72Å; F177-M181 HydrophobicContact CE2-SD 4.21Å; F177-M181 HydrophobicContact CZ-CG 3.61Å; F177-M181 HydrophobicContact CZ-SD 4.08Å; F177-M181 WeakPolarHBondContact O-CB 3.41Å; F177-M181 VanDerWaalsContact O-CG 3.28Å; F177-M181 WeakPolarHBondContact O-CG 3.46Å; F177-M181 PolarHBondContact O-N 3.39Å
178	V	87.1	Confident	84	Confident	56 Å²	56	33.9 Å²	33.9	34%	0.339	20%	0.201	S	C	.	.	H	α-helix	trans	-64.8	-43.6	179.3	170.4	0	0	0	0	110.5	L174 I175 I180 M181 L182 H303	L174-V178 WeakPolarHBondContact O-CG2 3.46Å; L174-V178 PolarHBondContact O-N 3.48Å; I175-V178 PolarHBondContact O-N 3.5Å; V178-I180 PolarHBondContact O-N 2.85Å; V178-M181 PolarHBondContact O-N 2.76Å; V178-M181 VanDerWaalsContact O-N 3.13Å; V178-L182 HydrophobicContact CG1-CG 4.48Å; V178-L182 WeakPolarHBondContact O-CG 3.45Å; V178-L182 PolarHBondContact O-N 3.38Å; V178-H303 VanDerWaalsContact CG1-CE1 3.44Å; V178-H303 WeakPolarHBondContact CG1-CE1 3.26Å
179	A	82.4	Confident	85	Confident	7 Å²	7	31.6 Å²	31.6	6%	0.058	18%	0.18	C	C	.	.	H	α-helix	trans	-57.1	-49.1	174.8	0	0	0	0	0	111.5	E57 I175 V176 M181 L182 H183	E57-A179 HydrophobicContact CB-CB 4.15Å; E57-A179 HydrophobicContact CG-CB 3.81Å; I175-A179 WeakPolarHBondContact O-CB 3.42Å; I175-A179 PolarHBondContact O-N 2.92Å; V176-A179 PolarHBondContact O-N 3.27Å; A179-M181 VanDerWaalsContact C-N 3.28Å; A179-M181 PolarHBondContact O-N 2.85Å; A179-L182 PolarHBondContact O-N 3.1Å; A179-H183 PolarHBondContact O-N 3.16Å; A179-H183 PolarHBondContact O-ND1 2.92Å
180	I	87.5	Confident	85.4	Confident	0 Å²	0	28.4 Å²	28.4	0%	0	17%	0.165	C	C	.	.	H	α-helix	trans	-57.4	-44.1	174.4	-69	166.6	0	0	0	111	M14 D157 L161 V176 F177 V178 L182 H183 K184	M14-I180 HydrophobicContact CE-CG2 4.09Å; M14-I180 HydrophobicContact SD-CG2 4.11Å; D157-I180 HydrophobicContact CB-CD1 4.26Å; D157-I180 HydrophobicContact CB-CG1 4.36Å; D157-I180 HydrophobicContact CB-CG2 4.08Å; D157-I180 WeakPolarHBondContact O-CD1 3.25Å; L161-I180 HydrophobicContact CB-CD1 3.88Å; V176-I180 HydrophobicContact CG1-CD1 3.67Å; V176-I180 HydrophobicContact CG1-CG1 4.39Å; V176-I180 WeakPolarHBondContact O-CB 3.26Å; V176-I180 VanDerWaalsContact O-CG1 3.23Å; V176-I180 WeakPolarHBondContact O-CG1 3.43Å; V176-I180 PolarHBondContact O-N 3.38Å; F177-I180 PolarHBondContact O-N 3.32Å; V178-I180 PolarHBondContact O-N 2.85Å; I180-L182 PolarHBondContact O-N 3.27Å; I180-H183 WeakPolarHBondContact CA-CE1 3.36Å; I180-H183 WeakPolarHBondContact CA-ND1 3.32Å; I180-H183 PolarHBondContact O-N 3.38Å; I180-K184 HydrophobicContact CG2-CD 4.35Å; I180-K184 WeakPolarHBondContact O-CB 3.33Å; I180-K184 PolarHBondContact O-N 3.28Å
181	M	88	Confident	85.7	Confident	29 Å²	29	25.2 Å²	25.2	14%	0.143	15%	0.146	C	C	.	.	H	α-helix	trans	-67.2	-38.9	-177.8	-76.3	-82.8	65.4	0	0	113.9	M14 A17 F177 V178 A179 H183 K184 A185	M14-M181 HydrophobicContact CB-CE 4.35Å; M14-M181 HydrophobicContact CB-SD 4.15Å; M14-M181 HydrophobicContact CG-CE 3.61Å; M14-M181 HydrophobicContact CG-SD 3.99Å; A17-M181 HydrophobicContact CB-CE 4.27Å; A17-M181 HydrophobicContact CB-SD 3.82Å; F177-M181 HydrophobicContact CD1-CG 4.41Å; F177-M181 HydrophobicContact CD2-CG 4.19Å; F177-M181 HydrophobicContact CE1-CG 3.97Å; F177-M181 HydrophobicContact CE2-CG 3.72Å; F177-M181 HydrophobicContact CE2-SD 4.21Å; F177-M181 HydrophobicContact CZ-CG 3.61Å; F177-M181 HydrophobicContact CZ-SD 4.08Å; F177-M181 WeakPolarHBondContact O-CB 3.41Å; F177-M181 VanDerWaalsContact O-CG 3.28Å; F177-M181 WeakPolarHBondContact O-CG 3.46Å; F177-M181 PolarHBondContact O-N 3.39Å; V178-M181 PolarHBondContact O-N 2.76Å; V178-M181 VanDerWaalsContact O-N 3.13Å; A179-M181 VanDerWaalsContact C-N 3.28Å; A179-M181 PolarHBondContact O-N 2.85Å; M181-H183 PolarHBondContact O-N 3.46Å; M181-K184 HydrophobicContact CE-CB 3.72Å; M181-K184 HydrophobicContact CE-CD 3.8Å; M181-K184 HydrophobicContact CE-CG 4.08Å; M181-K184 PolarHBondContact O-N 3.04Å; M181-A185 PolarHBondContact O-N 3.48Å
182	L	84.3	Confident	86.2	Confident	37 Å²	37	21 Å²	21	19%	0.194	12%	0.117	C	C	.	.	H	α-helix	trans	-60.6	-34.8	176.2	-79.4	-178	0	0	0	112.6	V53 V178 A179 I180 P186 H303	V53-L182 HydrophobicContact CG1-CB 4.03Å; V178-L182 HydrophobicContact CG1-CG 4.48Å; V178-L182 WeakPolarHBondContact O-CG 3.45Å; V178-L182 PolarHBondContact O-N 3.38Å; A179-L182 PolarHBondContact O-N 3.1Å; I180-L182 PolarHBondContact O-N 3.27Å; L182-P186 WeakPolarHBondContact O-CD 3.23Å; L182-P186 VanDerWaalsContact O-CG 3.23Å; L182-P186 WeakPolarHBondContact O-CG 3.42Å; L182-H303 VanDerWaalsContact CD1-CE1 3.41Å; L182-H303 WeakPolarHBondContact CD1-CE1 3.3Å; L182-H303 VanDerWaalsContact CD1-ND1 3.28Å; L182-H303 WeakPolarHBondContact CD1-ND1 3.3Å
183	H	84.8	Confident	86.7	Confident	2 Å²	2	20.5 Å²	20.5	1%	0.009	11%	0.113	C	C	.	.	H	α-helix	trans	-91	-25.7	178.7	64.5	-115.1	0	0	0	114.6	T49 V53 I54 D157 A179 I180 M181 P186 A187	T49-H183 VanDerWaalsContact CG2-CA 3.45Å; T49-H183 HydrophobicContact CG2-CB 3.02Å; V53-H183 HydrophobicContact CB-CB 4.3Å; V53-H183 HydrophobicContact CG1-CB 3.97Å; I54-H183 HydrophobicContact CD1-CB 4.23Å; I54-H183 HydrophobicContact CG1-CB 4Å; D157-H183 IonicContact OD1-NE2 3.14Å; D157-H183 IonicContact OD2-NE2 3.28Å; A179-H183 PolarHBondContact O-N 3.16Å; A179-H183 PolarHBondContact O-ND1 2.92Å; I180-H183 WeakPolarHBondContact CA-CE1 3.36Å; I180-H183 WeakPolarHBondContact CA-ND1 3.32Å; I180-H183 PolarHBondContact O-N 3.38Å; M181-H183 PolarHBondContact O-N 3.46Å; H183-P186 WeakPolarHBondContact O-CD 3.44Å; H183-A187 VanDerWaalsContact O-CB 3.25Å; H183-A187 WeakPolarHBondContact O-CB 3.45Å; H183-A187 PolarHBondContact O-N 3.12Å
184	K	88.4	Confident	86.7	Confident	1 Å²	1	20.6 Å²	20.6	0%	0.004	11%	0.114	C	C	.	.	H	α-helix	trans	-74.7	-32.9	-175.7	-167.1	167.9	-163.3	67.5	0	113.4	M14 C18 D157 I180 M181 A187 A188 F212	M14-K184 HydrophobicContact CG-CD 3.7Å; M14-K184 HydrophobicContact SD-CD 3.89Å; C18-K184 HydrophobicContact CB-CD 4.05Å; C18-K184 HydrophobicContact CB-CG 4Å; D157-K184 IonicContact OD2-NZ 2.65Å; I180-K184 HydrophobicContact CG2-CD 4.35Å; I180-K184 WeakPolarHBondContact O-CB 3.33Å; I180-K184 PolarHBondContact O-N 3.28Å; M181-K184 HydrophobicContact CE-CB 3.72Å; M181-K184 HydrophobicContact CE-CD 3.8Å; M181-K184 HydrophobicContact CE-CG 4.08Å; M181-K184 PolarHBondContact O-N 3.04Å; K184-A187 PolarHBondContact O-N 3.31Å; K184-A188 WeakPolarHBondContact O-CB 3.29Å; K184-A188 PolarHBondContact O-N 3.38Å; K184-F212 HydrophobicContact CG-CE1 4.35Å
185	A	86.8	Confident	86.6	Confident	34 Å²	34	16.7 Å²	16.7	28%	0.281	9%	0.093	S	C	.	.	H	α-helix	trans	-67.2	-50.1	174.9	0	0	0	0	0	112.5	A21 M181 A187 A188 F189	A21-A185 HydrophobicContact CB-CB 3.68Å; M181-A185 PolarHBondContact O-N 3.48Å; A185-A187 VanDerWaalsContact C-N 3.3Å; A185-A187 PolarHBondContact O-N 3.48Å; A185-A188 PolarHBondContact O-N 2.79Å; A185-F189 PolarHBondContact O-N 3.04Å
186	P	84.9	Confident	86.8	Confident	17 Å²	17	14.1 Å²	14.1	11%	0.11	8%	0.08	C	C	.	.	H	α-helix	trans	-57.1	-39.7	169.7	-26.3	34.8	0	0	0	113.4	L45 L182 H183 F189 G190	L45-P186 HydrophobicContact CB-CB 4.31Å; L45-P186 HydrophobicContact CD2-CB 4.46Å; L182-P186 WeakPolarHBondContact O-CD 3.23Å; L182-P186 VanDerWaalsContact O-CG 3.23Å; L182-P186 WeakPolarHBondContact O-CG 3.42Å; H183-P186 WeakPolarHBondContact O-CD 3.44Å; P186-F189 PolarHBondContact O-N 2.98Å; P186-G190 PolarHBondContact O-N 3.28Å
187	A	86.3	Confident	86.7	Confident	0 Å²	0	16 Å²	16	0%	0	9%	0.088	C	C	.	.	H	α-helix	trans	-61.7	-47	176.7	0	0	0	0	0	112.6	L46 H183 K184 A185 F189 G190 L191 F212 F252	L46-A187 HydrophobicContact CD2-CB 4.33Å; H183-A187 VanDerWaalsContact O-CB 3.25Å; H183-A187 WeakPolarHBondContact O-CB 3.45Å; H183-A187 PolarHBondContact O-N 3.12Å; K184-A187 PolarHBondContact O-N 3.31Å; A185-A187 VanDerWaalsContact C-N 3.3Å; A185-A187 PolarHBondContact O-N 3.48Å; A187-F189 VanDerWaalsContact C-N 3.32Å; A187-F189 PolarHBondContact O-N 2.83Å; A187-G190 PolarHBondContact O-N 2.85Å; A187-L191 WeakPolarHBondContact O-CB 3.4Å; A187-L191 PolarHBondContact O-N 3.39Å; A187-F212 HydrophobicContact CB-CZ 3.98Å; A187-F252 HydrophobicContact CB-CE2 3.93Å; A187-F252 HydrophobicContact CB-CZ 3.52Å
188	A	91.1	Very high	86.2	Confident	0 Å²	0	15.6 Å²	15.6	0%	0	9%	0.09	C	C	.	.	H	α-helix	trans	-61.8	-41	176.7	0	0	0	0	0	111.9	C18 K184 A185 V192 L209 F212	C18-A188 WeakPolarHBondContact O-CB 3.04Å; K184-A188 WeakPolarHBondContact O-CB 3.29Å; K184-A188 PolarHBondContact O-N 3.38Å; A185-A188 PolarHBondContact O-N 2.79Å; A188-V192 WeakPolarHBondContact O-CG2 3.36Å; A188-V192 PolarHBondContact O-N 3.21Å; A188-V192 VanDerWaalsContact O-N 3.09Å; A188-L209 HydrophobicContact CB-CD1 4.2Å; A188-F212 HydrophobicContact CB-CD1 4.46Å; A188-F212 HydrophobicContact CB-CE1 3.99Å
189	F	89.6	Confident	85.9	Confident	42 Å²	42	16 Å²	16	18%	0.184	11%	0.105	C	C	.	.	H	α-helix	trans	-61.5	-47.2	175	-179.6	-81	0	0	0	111.8	P25 V38 L45 A185 P186 A187 V192 S193	P25-F189 HydrophobicContact CB-CE2 4.49Å; P25-F189 HydrophobicContact CG-CD2 3.46Å; P25-F189 VanDerWaalsContact CG-CD2 3.46Å; P25-F189 HydrophobicContact CG-CE2 3.65Å; P25-F189 HydrophobicContact CG-CG 3.97Å; P25-F189 HydrophobicContact CG-CZ 4.29Å; V38-F189 HydrophobicContact CG1-CE1 4.04Å; V38-F189 HydrophobicContact CG1-CZ 3.86Å; L45-F189 HydrophobicContact CD1-CD1 3.66Å; L45-F189 HydrophobicContact CD1-CE1 4.05Å; L45-F189 HydrophobicContact CD1-CG 4.49Å; A185-F189 PolarHBondContact O-N 3.04Å; P186-F189 PolarHBondContact O-N 2.98Å; A187-F189 VanDerWaalsContact C-N 3.32Å; A187-F189 PolarHBondContact O-N 2.83Å; F189-V192 PolarHBondContact O-N 3.37Å; F189-S193 WeakPolarHBondContact CE1-OG 3.45Å; F189-S193 VanDerWaalsContact O-CB 3.3Å; F189-S193 WeakPolarHBondContact O-CB 3.5Å; F189-S193 PolarHBondContact O-N 2.99Å; F189-S193 PolarHBondContact O-OG 3.24Å
190	G	85.8	Confident	86	Confident	2 Å²	2	16.8 Å²	16.8	2%	0.021	11%	0.108	C	C	.	.	H	α-helix	trans	-63.1	-45.3	178.8	0	0	0	0	0	112.5	P186 A187 V192 S193 F194	P186-G190 PolarHBondContact O-N 3.28Å; A187-G190 PolarHBondContact O-N 2.85Å; G190-V192 PolarHBondContact O-N 3.19Å; G190-S193 PolarHBondContact O-N 3.08Å; G190-F194 WeakPolarHBondContact O-CB 3.19Å; G190-F194 PolarHBondContact O-N 3.29Å
191	L	86.8	Confident	86.1	Confident	1 Å²	1	22.5 Å²	22.5	1%	0.005	14%	0.135	C	C	.	.	H	α-helix	trans	-56.2	-51.4	175.7	170.3	61.6	0	0	0	111.6	L150 A187 F194 L195 F212	L150-L191 HydrophobicContact CD1-CB 3.89Å; L150-L191 HydrophobicContact CD1-CD1 3.32Å; L150-L191 HydrophobicContact CD1-CD2 4.32Å; L150-L191 HydrophobicContact CD1-CG 3.99Å; A187-L191 WeakPolarHBondContact O-CB 3.4Å; A187-L191 PolarHBondContact O-N 3.39Å; L191-F194 PolarHBondContact O-N 2.99Å; L191-L195 HydrophobicContact CD1-CD1 3.85Å; L191-L195 HydrophobicContact CD1-CG 3.98Å; L191-L195 HydrophobicContact CG-CD1 4.21Å; L191-L195 WeakPolarHBondContact O-CG 3.47Å; L191-L195 PolarHBondContact O-N 2.99Å; L191-F212 HydrophobicContact CD2-CB 3.87Å; L191-F212 HydrophobicContact CD2-CD1 4.18Å; L191-F212 HydrophobicContact CD2-CD2 4.2Å; L191-F212 HydrophobicContact CD2-CG 3.81Å
192	V	90.8	Very high	86.1	Confident	0 Å²	0	26.6 Å²	26.6	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-69.8	-40.5	-174.8	171.1	0	0	0	0	111.3	G22 P25 L26 A188 F189 G190 F194 L195 M196 I205 L209	G22-V192 WeakPolarHBondContact O-CB 3.08Å; G22-V192 WeakPolarHBondContact O-CG1 3.18Å; G22-V192 VanDerWaalsContact O-CG2 3.32Å; G22-V192 WeakPolarHBondContact O-CG2 3.34Å; P25-V192 HydrophobicContact CB-CG1 3.95Å; P25-V192 HydrophobicContact CG-CB 4.25Å; P25-V192 HydrophobicContact CG-CG1 4.11Å; L26-V192 HydrophobicContact CD1-CG1 3.82Å; L26-V192 HydrophobicContact CD2-CG1 4.4Å; L26-V192 HydrophobicContact CG-CG1 3.54Å; A188-V192 WeakPolarHBondContact O-CG2 3.36Å; A188-V192 PolarHBondContact O-N 3.21Å; A188-V192 VanDerWaalsContact O-N 3.09Å; F189-V192 PolarHBondContact O-N 3.37Å; G190-V192 PolarHBondContact O-N 3.19Å; V192-F194 VanDerWaalsContact C-N 3.31Å; V192-F194 PolarHBondContact O-N 3.02Å; V192-L195 PolarHBondContact O-N 3.42Å; V192-M196 HydrophobicContact CG1-CG 4.35Å; V192-M196 HydrophobicContact CG1-SD 4.03Å; V192-M196 WeakPolarHBondContact O-CB 3.46Å; V192-M196 VanDerWaalsContact O-CG 3.27Å; V192-M196 WeakPolarHBondContact O-CG 3.4Å; V192-M196 PolarHBondContact O-N 3.11Å; V192-I205 HydrophobicContact CB-CG2 4.44Å; V192-I205 HydrophobicContact CG1-CG2 3.91Å; V192-I205 HydrophobicContact CG2-CG2 4.19Å; V192-L209 HydrophobicContact CG2-CB 4.24Å; V192-L209 HydrophobicContact CG2-CD1 4.05Å; V192-L209 HydrophobicContact CG2-CD2 4.17Å; V192-L209 HydrophobicContact CG2-CG 4.38Å
193	S	87.5	Confident	86.5	Confident	1 Å²	1	29.4 Å²	29.4	1%	0.007	16%	0.164	C	C	.	.	H	α-helix	trans	-56.5	-46.4	173.6	-61.5	0	0	0	0	111.4	V38 T39 F189 G190 M196 H197	V38-S193 WeakPolarHBondContact CG1-OG 3.35Å; T39-S193 PolarHBondContact OG1-O 3.29Å; F189-S193 WeakPolarHBondContact CE1-OG 3.45Å; F189-S193 VanDerWaalsContact O-CB 3.3Å; F189-S193 WeakPolarHBondContact O-CB 3.5Å; F189-S193 PolarHBondContact O-N 2.99Å; F189-S193 PolarHBondContact O-OG 3.24Å; G190-S193 PolarHBondContact O-N 3.08Å; S193-M196 PolarHBondContact O-N 3.26Å; S193-H197 WeakPolarHBondContact O-CB 3.38Å; S193-H197 PolarHBondContact O-N 2.96Å
194	F	84.8	Confident	86.6	Confident	5 Å²	5	34.8 Å²	34.8	2%	0.022	19%	0.185	C	C	.	.	H	α-helix	trans	-60.6	-49.1	175	173.4	-96.5	0	0	0	112.5	T39 T146 G190 L191 V192 M196 H197 A198 V260 E263	T39-F194 HydrophobicContact CG2-CB 4.37Å; T39-F194 HydrophobicContact CG2-CD2 4.38Å; T146-F194 HydrophobicContact CG2-CD1 4.03Å; T146-F194 HydrophobicContact CG2-CE1 3.75Å; T146-F194 HydrophobicContact CG2-CZ 4.38Å; G190-F194 WeakPolarHBondContact O-CB 3.19Å; G190-F194 PolarHBondContact O-N 3.29Å; L191-F194 PolarHBondContact O-N 2.99Å; V192-F194 VanDerWaalsContact C-N 3.31Å; V192-F194 PolarHBondContact O-N 3.02Å; F194-M196 VanDerWaalsContact C-N 3.28Å; F194-M196 PolarHBondContact O-N 3.39Å; F194-H197 PolarHBondContact O-N 2.91Å; F194-H197 VanDerWaalsContact O-N 3.12Å; F194-A198 WeakPolarHBondContact O-CB 3.25Å; F194-A198 PolarHBondContact O-N 3.15Å; F194-V260 HydrophobicContact CD2-CG1 4.23Å; F194-E263 HydrophobicContact CE2-CB 4.23Å; F194-E263 HydrophobicContact CE2-CG 3.99Å
195	L	85.8	Confident	86.8	Confident	0 Å²	0	34.9 Å²	34.9	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-64.8	-32.7	-179.3	-68.4	-179.8	0	0	0	112.9	L191 V192 G199 L200 I205 H208	L191-L195 HydrophobicContact CD1-CD1 3.85Å; L191-L195 HydrophobicContact CD1-CG 3.98Å; L191-L195 HydrophobicContact CG-CD1 4.21Å; L191-L195 WeakPolarHBondContact O-CG 3.47Å; L191-L195 PolarHBondContact O-N 2.99Å; V192-L195 PolarHBondContact O-N 3.42Å; L195-G199 PolarHBondContact O-N 2.92Å; L195-L200 HydrophobicContact CD2-CD1 4.1Å; L195-L200 HydrophobicContact CD2-CD2 4.18Å; L195-L200 PolarHBondContact O-N 3.44Å; L195-I205 HydrophobicContact CB-CD1 4.18Å; L195-I205 HydrophobicContact CB-CG1 3.97Å; L195-I205 HydrophobicContact CB-CG2 4.13Å; L195-I205 HydrophobicContact CD1-CG2 4.12Å; L195-H208 HydrophobicContact CD1-CB 3.7Å
196	M	86.4	Confident	87.1	Confident	30 Å²	30	38.6 Å²	38.6	15%	0.148	19%	0.192	C	C	.	.	H	α-helix	trans	-65.8	-45.2	172	-73	175.8	62.6	0	0	111	P25 L26 F30 L35 V192 S193 F194 A198 G199 I205	P25-M196 VanDerWaalsContact C-SD 3.57Å; P25-M196 HydrophobicContact CB-SD 3.91Å; P25-M196 WeakPolarHBondContact O-CE 3.42Å; L26-M196 HydrophobicContact CD2-CG 3.99Å; L26-M196 HydrophobicContact CD2-SD 3.91Å; L26-M196 HydrophobicContact CG-SD 4.06Å; F30-M196 HydrophobicContact CD2-CE 4.05Å; L35-M196 HydrophobicContact CD1-CB 3.87Å; L35-M196 HydrophobicContact CD1-CE 4.24Å; L35-M196 HydrophobicContact CD2-CB 4.46Å; V192-M196 HydrophobicContact CG1-CG 4.35Å; V192-M196 HydrophobicContact CG1-SD 4.03Å; V192-M196 WeakPolarHBondContact O-CB 3.46Å; V192-M196 VanDerWaalsContact O-CG 3.27Å; V192-M196 WeakPolarHBondContact O-CG 3.4Å; V192-M196 PolarHBondContact O-N 3.11Å; S193-M196 PolarHBondContact O-N 3.26Å; F194-M196 VanDerWaalsContact C-N 3.28Å; F194-M196 PolarHBondContact O-N 3.39Å; M196-A198 VanDerWaalsContact C-N 3.3Å; M196-A198 PolarHBondContact O-N 3.12Å; M196-G199 PolarHBondContact O-N 2.97Å; M196-I205 HydrophobicContact CB-CD1 4.34Å; M196-I205 HydrophobicContact CG-CD1 3.64Å
197	H	82.4	Confident	87.4	Confident	44 Å²	44	44.6 Å²	44.6	20%	0.204	22%	0.216	C	C	.	.	H	α-helix	trans	-65.6	-33.9	177.3	-169.1	65	0	0	0	112.7	L35 T39 S193 F194 G199	L35-H197 HydrophobicContact CD2-CB 4.35Å; L35-H197 HydrophobicContact CG-CB 4.1Å; T39-H197 HydrophobicContact CG2-CB 4.14Å; T39-H197 WeakPolarHBondContact OG1-CB 3.34Å; S193-H197 WeakPolarHBondContact O-CB 3.38Å; S193-H197 PolarHBondContact O-N 2.96Å; F194-H197 PolarHBondContact O-N 2.91Å; F194-H197 VanDerWaalsContact O-N 3.12Å; H197-G199 PolarHBondContact O-N 3.29Å; H197-G199 VanDerWaalsContact O-N 3.16Å
198	A	78	Confident	87.7	Confident	20 Å²	20	46.1 Å²	46.1	17%	0.165	22%	0.223	C	C	.	.	T	Hydrogen-bonded Turn	trans	-69.7	-3.3	173	0	0	0	0	0	114	K143 F194 M196 L200	K143-A198 HydrophobicContact CD-CB 4.13Å; K143-A198 HydrophobicContact CG-CB 4.14Å; K143-A198 PolarHBondContact NZ-O 3.08Å; F194-A198 WeakPolarHBondContact O-CB 3.25Å; F194-A198 PolarHBondContact O-N 3.15Å; M196-A198 VanDerWaalsContact C-N 3.3Å; M196-A198 PolarHBondContact O-N 3.12Å; A198-L200 HydrophobicContact CB-CD1 3.74Å
199	G	82.2	Confident	87.8	Confident	64 Å²	64	46.1 Å²	46.1	66%	0.66	22%	0.223	S	C	*	.	T	Hydrogen-bonded Turn	trans	77.8	19.8	174.5	0	0	0	0	0	115	L195 M196 H197	L195-G199 PolarHBondContact O-N 2.92Å; M196-G199 PolarHBondContact O-N 2.97Å; H197-G199 PolarHBondContact O-N 3.29Å; H197-G199 VanDerWaalsContact O-N 3.16Å
200	L	84.8	Confident	88.1	Confident	23 Å²	23	47.9 Å²	47.9	12%	0.12	23%	0.234	C	C	.	.			trans	-68.5	146.2	176.4	-80.2	82.4	0	0	0	111.4	K143 L195 A198 R204 I205	K143-L200 HydrophobicContact CB-CD1 4.37Å; K143-L200 HydrophobicContact CD-CD1 3.75Å; K143-L200 HydrophobicContact CG-CD1 4.17Å; L195-L200 HydrophobicContact CD2-CD1 4.1Å; L195-L200 HydrophobicContact CD2-CD2 4.18Å; L195-L200 PolarHBondContact O-N 3.44Å; A198-L200 HydrophobicContact CB-CD1 3.74Å; L200-R204 HydrophobicContact CD2-CB 4.28Å; L200-I205 HydrophobicContact CB-CD1 4.08Å; L200-I205 HydrophobicContact CB-CG1 3.65Å; L200-I205 WeakPolarHBondContact O-CD1 3.27Å
201	E	89.4	Confident	88.4	Confident	121 Å²	121	51.5 Å²	51.5	57%	0.565	26%	0.256	S	S	*	.			trans	-63.4	143.5	171.3	62.2	172.6	162.2	0	0	111.7	N203 R204 I205	E201-N203 PolarHBondContact O-N 3Å; E201-N203 VanDerWaalsContact O-N 3.08Å; E201-R204 HydrophobicContact CG-CB 3.75Å; E201-R204 HydrophobicContact CG-CG 3.56Å; E201-R204 PolarHBondContact O-N 3.47Å; E201-R204 WeakPolarHBondContact OE1-CD 3.42Å; E201-R204 WeakPolarHBondContact OE1-CG 3.38Å; E201-I205 WeakPolarHBondContact O-CG1 3.49Å; E201-I205 PolarHBondContact O-N 3.24Å
202	R	88.3	Confident	88.7	Confident	115 Å²	115	51.5 Å²	51.5	43%	0.434	26%	0.256	S	S	.	.	H	α-helix	trans	-53.6	-36.5	-175.4	-66.2	177.3	175	-109.5	4.5	113.3	L26 N29 I205 R206	L26-R202 HydrophobicContact CD2-CB 4.45Å; L26-R202 HydrophobicContact CD2-CG 4.19Å; L26-R202 PolarHBondContact O-NH1 3.48Å; N29-R202 PolarHBondContact OD1-NH2 3.27Å; R202-I205 PolarHBondContact O-N 3.03Å; R202-R206 WeakPolarHBondContact O-CG 3.47Å; R202-R206 PolarHBondContact O-N 3.24Å
203	N	91.4	Very high	88.9	Confident	96 Å²	96	51.5 Å²	51.5	51%	0.513	26%	0.256	S	S	.	.	H	α-helix	trans	-69.5	-36.1	178.5	-81.5	-1.4	0	0	0	112.9	E201 R206 K207	E201-N203 PolarHBondContact O-N 3Å; E201-N203 VanDerWaalsContact O-N 3.08Å; N203-R206 PolarHBondContact OD1-NH1 3.3Å; N203-K207 WeakPolarHBondContact O-CG 3.32Å; N203-K207 PolarHBondContact O-N 3.35Å
204	R	88.3	Confident	89.3	Confident	115 Å²	115	54.6 Å²	54.6	43%	0.434	27%	0.272	S	S	.	.	H	α-helix	trans	-68	-42.9	172.4	-75.6	177.7	79.2	-177	3.3	110.3	L200 E201 R206 K207 H208	L200-R204 HydrophobicContact CD2-CB 4.28Å; E201-R204 HydrophobicContact CG-CB 3.75Å; E201-R204 HydrophobicContact CG-CG 3.56Å; E201-R204 PolarHBondContact O-N 3.47Å; E201-R204 WeakPolarHBondContact OE1-CD 3.42Å; E201-R204 WeakPolarHBondContact OE1-CG 3.38Å; R204-R206 VanDerWaalsContact C-N 3.31Å; R204-R206 PolarHBondContact O-N 2.68Å; R204-K207 WeakPolarHBondContact O-CB 3.24Å; R204-K207 PolarHBondContact O-N 2.93Å; R204-H208 PolarHBondContact O-N 2.89Å; R204-H208 PolarHBondContact O-ND1 3.32Å
205	I	91	Very high	89.9	Confident	2 Å²	2	55 Å²	55	1%	0.01	28%	0.276	C	S	.	.	H	α-helix	trans	-57.9	-45.6	177.5	-57.5	178.6	0	0	0	110.8	L26 V192 L195 M196 L200 E201 R202 K207 H208 L209	L26-I205 HydrophobicContact CD1-CB 4.41Å; L26-I205 HydrophobicContact CD1-CG2 3.82Å; L26-I205 HydrophobicContact CD2-CB 4.3Å; L26-I205 HydrophobicContact CD2-CD1 4.1Å; L26-I205 HydrophobicContact CD2-CG2 4.11Å; L26-I205 HydrophobicContact CG-CG2 4.27Å; V192-I205 HydrophobicContact CB-CG2 4.44Å; V192-I205 HydrophobicContact CG1-CG2 3.91Å; V192-I205 HydrophobicContact CG2-CG2 4.19Å; L195-I205 HydrophobicContact CB-CD1 4.18Å; L195-I205 HydrophobicContact CB-CG1 3.97Å; L195-I205 HydrophobicContact CB-CG2 4.13Å; L195-I205 HydrophobicContact CD1-CG2 4.12Å; M196-I205 HydrophobicContact CB-CD1 4.34Å; M196-I205 HydrophobicContact CG-CD1 3.64Å; L200-I205 HydrophobicContact CB-CD1 4.08Å; L200-I205 HydrophobicContact CB-CG1 3.65Å; L200-I205 WeakPolarHBondContact O-CD1 3.27Å; E201-I205 WeakPolarHBondContact O-CG1 3.49Å; E201-I205 PolarHBondContact O-N 3.24Å; R202-I205 PolarHBondContact O-N 3.03Å; I205-K207 VanDerWaalsContact C-N 3.28Å; I205-K207 PolarHBondContact O-N 3.37Å; I205-H208 PolarHBondContact O-N 2.92Å; I205-L209 WeakPolarHBondContact O-CB 3.4Å; I205-L209 PolarHBondContact O-N 2.82Å
206	R	93.4	Very high	90.3	Very high	112 Å²	112	55 Å²	55	42%	0.423	28%	0.276	S	S	.	.	H	α-helix	trans	-57.6	-37.5	175	-73.5	173.7	-178.1	156.6	-5.6	113.2	I23 L26 R202 N203 R204 L210	I23-R206 HydrophobicContact CD1-CG 4.27Å; L26-R206 HydrophobicContact CD1-CG 4.3Å; R202-R206 WeakPolarHBondContact O-CG 3.47Å; R202-R206 PolarHBondContact O-N 3.24Å; N203-R206 PolarHBondContact OD1-NH1 3.3Å; R204-R206 VanDerWaalsContact C-N 3.31Å; R204-R206 PolarHBondContact O-N 2.68Å; R206-L210 WeakPolarHBondContact O-CB 3.36Å; R206-L210 PolarHBondContact O-N 3.36Å
207	K	92.4	Very high	90.7	Very high	143 Å²	143	54.1 Å²	54.1	62%	0.622	27%	0.272	S	S	*	.	H	α-helix	trans	-67.1	-46.9	175.4	-70.1	176.4	-177.8	-179.3	0	111.7	N203 R204 I205 L209 L210 V211	N203-K207 WeakPolarHBondContact O-CG 3.32Å; N203-K207 PolarHBondContact O-N 3.35Å; R204-K207 WeakPolarHBondContact O-CB 3.24Å; R204-K207 PolarHBondContact O-N 2.93Å; I205-K207 VanDerWaalsContact C-N 3.28Å; I205-K207 PolarHBondContact O-N 3.37Å; K207-L209 VanDerWaalsContact C-N 3.34Å; K207-L209 PolarHBondContact O-N 3.04Å; K207-L210 PolarHBondContact O-N 3.13Å; K207-V211 WeakPolarHBondContact O-CG2 3.49Å; K207-V211 PolarHBondContact O-N 3.25Å
208	H	91.4	Very high	91.4	Very high	33 Å²	33	55.9 Å²	55.9	15%	0.153	29%	0.286	C	S	.	.	H	α-helix	trans	-61.9	-43.1	177.6	-66.4	79.3	0	0	0	110.8	T147 L195 R204 I205 L210 V211 F212	T147-H208 HydrophobicContact CG2-CB 3.82Å; T147-H208 PolarHBondContact OG1-CD2 3.18Å; L195-H208 HydrophobicContact CD1-CB 3.7Å; R204-H208 PolarHBondContact O-N 2.89Å; R204-H208 PolarHBondContact O-ND1 3.32Å; I205-H208 PolarHBondContact O-N 2.92Å; H208-L210 PolarHBondContact O-N 3.29Å; H208-V211 PolarHBondContact O-N 3.4Å; H208-F212 WeakPolarHBondContact O-CB 3.26Å; H208-F212 PolarHBondContact O-N 3.42Å
209	L	93.4	Very high	92.2	Very high	0 Å²	0	57.8 Å²	57.8	0%	0	29%	0.292	C	S	.	.	H	α-helix	trans	-60.5	-42.7	174.1	176.3	61.8	0	0	0	112.3	Y19 I23 A188 V192 I205 K207 F212 A213	Y19-L209 HydrophobicContact CD2-CD2 3.97Å; Y19-L209 HydrophobicContact CD2-CG 3.88Å; Y19-L209 HydrophobicContact CE2-CD2 4Å; Y19-L209 HydrophobicContact CE2-CG 4.1Å; I23-L209 HydrophobicContact CD1-CD2 3.84Å; I23-L209 HydrophobicContact CG1-CD2 3.94Å; A188-L209 HydrophobicContact CB-CD1 4.2Å; V192-L209 HydrophobicContact CG2-CB 4.24Å; V192-L209 HydrophobicContact CG2-CD1 4.05Å; V192-L209 HydrophobicContact CG2-CD2 4.17Å; V192-L209 HydrophobicContact CG2-CG 4.38Å; I205-L209 WeakPolarHBondContact O-CB 3.4Å; I205-L209 PolarHBondContact O-N 2.82Å; K207-L209 VanDerWaalsContact C-N 3.34Å; K207-L209 PolarHBondContact O-N 3.04Å; L209-F212 PolarHBondContact O-N 3.19Å; L209-A213 VanDerWaalsContact O-CB 3.28Å; L209-A213 WeakPolarHBondContact O-CB 3.49Å; L209-A213 PolarHBondContact O-N 3.4Å
210	L	94.9	Very high	92.7	Very high	78 Å²	78	54.7 Å²	54.7	41%	0.408	26%	0.261	S	S	.	.	H	α-helix	trans	-63.6	-44.5	178.5	-179.1	62.5	0	0	0	111.5	Y19 R206 K207 H208 A213 L214	Y19-L210 HydrophobicContact CD2-CD1 4.4Å; Y19-L210 HydrophobicContact CE2-CB 4.21Å; Y19-L210 HydrophobicContact CE2-CD1 4.34Å; R206-L210 WeakPolarHBondContact O-CB 3.36Å; R206-L210 PolarHBondContact O-N 3.36Å; K207-L210 PolarHBondContact O-N 3.13Å; H208-L210 PolarHBondContact O-N 3.29Å; L210-A213 PolarHBondContact O-N 2.72Å; L210-L214 HydrophobicContact CD1-CD1 3.95Å; L210-L214 HydrophobicContact CD1-CG 4.18Å; L210-L214 HydrophobicContact CG-CD1 3.86Å; L210-L214 HydrophobicContact CG-CG 4.48Å; L210-L214 WeakPolarHBondContact O-CB 3.34Å; L210-L214 VanDerWaalsContact O-CG 3.3Å; L210-L214 WeakPolarHBondContact O-CG 3.29Å; L210-L214 PolarHBondContact O-N 3.49Å
211	V	93.6	Very high	93.1	Very high	79 Å²	79	55.5 Å²	55.5	48%	0.479	27%	0.265	S	S	.	.	H	α-helix	trans	-62.9	-44	177.1	178.5	0	0	0	0	110.5	V151 K207 H208 A213 L214 A215	V151-V211 HydrophobicContact CG1-CG1 4.25Å; V151-V211 HydrophobicContact CG2-CB 4.46Å; V151-V211 HydrophobicContact CG2-CG1 3.7Å; K207-V211 WeakPolarHBondContact O-CG2 3.49Å; K207-V211 PolarHBondContact O-N 3.25Å; H208-V211 PolarHBondContact O-N 3.4Å; V211-A213 PolarHBondContact O-N 2.72Å; V211-L214 PolarHBondContact O-N 2.95Å; V211-A215 PolarHBondContact O-N 3.31Å; V211-A215 VanDerWaalsContact O-N 3.07Å
212	F	92.9	Very high	93.3	Very high	1 Å²	1	53.6 Å²	53.6	0%	0.004	26%	0.261	C	S	.	.	H	α-helix	trans	-59.3	-45.3	174.6	174.5	-100.6	0	0	0	112.7	C18 L150 A154 K184 A187 A188 L191 H208 L209 L214 A215	C18-F212 WeakPolarHBondContact SG-CE1 2.95Å; L150-F212 HydrophobicContact CB-CD2 3.86Å; L150-F212 HydrophobicContact CB-CE2 3.97Å; L150-F212 VanDerWaalsContact O-CD2 3.3Å; L150-F212 WeakPolarHBondContact O-CD2 3.46Å; L150-F212 VanDerWaalsContact O-CE2 3.29Å; L150-F212 WeakPolarHBondContact O-CE2 3.3Å; A154-F212 HydrophobicContact CB-CD2 3.95Å; A154-F212 HydrophobicContact CB-CE2 3.82Å; A154-F212 HydrophobicContact CB-CZ 4.49Å; K184-F212 HydrophobicContact CG-CE1 4.35Å; A187-F212 HydrophobicContact CB-CZ 3.98Å; A188-F212 HydrophobicContact CB-CD1 4.46Å; A188-F212 HydrophobicContact CB-CE1 3.99Å; L191-F212 HydrophobicContact CD2-CB 3.87Å; L191-F212 HydrophobicContact CD2-CD1 4.18Å; L191-F212 HydrophobicContact CD2-CD2 4.2Å; L191-F212 HydrophobicContact CD2-CG 3.81Å; H208-F212 WeakPolarHBondContact O-CB 3.26Å; H208-F212 PolarHBondContact O-N 3.42Å; L209-F212 PolarHBondContact O-N 3.19Å; F212-L214 VanDerWaalsContact C-N 3.33Å; F212-L214 PolarHBondContact O-N 3.37Å; F212-A215 PolarHBondContact O-N 3.4Å
213	A	95.3	Very high	93.4	Very high	0 Å²	0	49.1 Å²	49.1	0%	0	25%	0.246	C	C	.	.	H	α-helix	trans	-69.7	-30.1	-178.7	0	0	0	0	0	112.7	L15 C18 L209 L210 V211 P217	L15-A213 HydrophobicContact CD1-CB 3.79Å; L15-A213 WeakPolarHBondContact CD1-O 3.24Å; C18-A213 HydrophobicContact CB-CB 4.15Å; L209-A213 VanDerWaalsContact O-CB 3.28Å; L209-A213 WeakPolarHBondContact O-CB 3.49Å; L209-A213 PolarHBondContact O-N 3.4Å; L210-A213 PolarHBondContact O-N 2.72Å; V211-A213 PolarHBondContact O-N 2.72Å; A213-P217 WeakPolarHBondContact O-CD 3.25Å; A213-P217 VanDerWaalsContact O-CG 3.28Å; A213-P217 WeakPolarHBondContact O-CG 3.49Å
214	L	96	Very high	93.3	Very high	65 Å²	65	45.7 Å²	45.7	34%	0.34	23%	0.226	S	C	.	.	H	α-helix	trans	-80.1	-27.6	177.4	-76.2	169.6	0	0	0	113.9	L15 L210 V211 F212 A216 P217 V218	L15-L214 HydrophobicContact CD1-CD2 3.69Å; L15-L214 HydrophobicContact CD1-CG 3.92Å; L15-L214 HydrophobicContact CD2-CD2 3.91Å; L15-L214 HydrophobicContact CG-CD2 4.47Å; L210-L214 HydrophobicContact CD1-CD1 3.95Å; L210-L214 HydrophobicContact CD1-CG 4.18Å; L210-L214 HydrophobicContact CG-CD1 3.86Å; L210-L214 HydrophobicContact CG-CG 4.48Å; L210-L214 WeakPolarHBondContact O-CB 3.34Å; L210-L214 VanDerWaalsContact O-CG 3.3Å; L210-L214 WeakPolarHBondContact O-CG 3.29Å; L210-L214 PolarHBondContact O-N 3.49Å; V211-L214 PolarHBondContact O-N 2.95Å; F212-L214 VanDerWaalsContact C-N 3.33Å; F212-L214 PolarHBondContact O-N 3.37Å; L214-A216 PolarHBondContact O-N 3.33Å; L214-P217 WeakPolarHBondContact O-CD 3.48Å; L214-V218 WeakPolarHBondContact O-CB 3.5Å; L214-V218 VanDerWaalsContact O-CG2 3.24Å; L214-V218 WeakPolarHBondContact O-CG2 3.33Å; L214-V218 PolarHBondContact O-N 3Å
215	A	95.8	Very high	93.3	Very high	13 Å²	13	43.4 Å²	43.4	11%	0.107	22%	0.222	C	C	.	.	H	α-helix	trans	-56.4	-48.5	-173.7	0	0	0	0	0	113.1	V151 A154 V211 F212 M219	V151-A215 HydrophobicContact CG1-CB 4.07Å; A154-A215 HydrophobicContact CB-CB 3.76Å; V211-A215 PolarHBondContact O-N 3.31Å; V211-A215 VanDerWaalsContact O-N 3.07Å; F212-A215 PolarHBondContact O-N 3.4Å; A215-M219 WeakPolarHBondContact O-CB 3.31Å; A215-M219 PolarHBondContact O-N 3.47Å
216	A	94.1	Very high	93.1	Very high	0 Å²	0	45.1 Å²	45.1	0%	0	24%	0.241	C	C	.	.	H	α-helix	trans	-68.3	-50	-179.8	0	0	0	0	0	113.2	M14 A154 D157 G158 L214 V218 M219 S220	M14-A216 HydrophobicContact SD-CB 3.43Å; M14-A216 WeakPolarHBondContact SD-CB 3.45Å; A154-A216 HydrophobicContact CB-CB 4.49Å; A154-A216 WeakPolarHBondContact O-CA 3.3Å; A154-A216 WeakPolarHBondContact O-CB 3.3Å; A154-A216 PolarHBondContact O-N 3.14Å; D157-A216 HydrophobicContact CB-CB 4.36Å; G158-A216 WeakPolarHBondContact CA-O 3.28Å; L214-A216 PolarHBondContact O-N 3.33Å; A216-V218 VanDerWaalsContact C-N 3.34Å; A216-V218 PolarHBondContact O-N 2.97Å; A216-M219 PolarHBondContact O-N 2.85Å; A216-S220 VanDerWaalsContact O-CB 3.24Å; A216-S220 WeakPolarHBondContact O-CB 3.46Å; A216-S220 PolarHBondContact O-N 2.62Å
217	P	95.8	Very high	92.5	Very high	12 Å²	12	41.8 Å²	41.8	8%	0.078	23%	0.231	C	C	.	.	H	α-helix	trans	-53.8	-45.8	173.4	-29.2	35	0	0	0	114	S11 L15 A213 L214 S220 M221	S11-P217 WeakPolarHBondContact O-CG 3.48Å; L15-P217 HydrophobicContact CB-CG 3.94Å; A213-P217 WeakPolarHBondContact O-CD 3.25Å; A213-P217 VanDerWaalsContact O-CG 3.28Å; A213-P217 WeakPolarHBondContact O-CG 3.49Å; L214-P217 WeakPolarHBondContact O-CD 3.48Å; P217-S220 PolarHBondContact O-N 3.16Å; P217-M221 PolarHBondContact O-N 3.44Å; P217-M221 VanDerWaalsContact O-N 3.12Å
218	V	96.3	Very high	91.6	Very high	81 Å²	81	38.9 Å²	38.9	49%	0.491	23%	0.229	S	C	.	.	H	α-helix	trans	-66.3	-49.1	-178.7	171.4	0	0	0	0	110.2	L214 A216 S220 M221 V222	L214-V218 WeakPolarHBondContact O-CB 3.5Å; L214-V218 VanDerWaalsContact O-CG2 3.24Å; L214-V218 WeakPolarHBondContact O-CG2 3.33Å; L214-V218 PolarHBondContact O-N 3Å; A216-V218 VanDerWaalsContact C-N 3.34Å; A216-V218 PolarHBondContact O-N 2.97Å; V218-S220 VanDerWaalsContact C-N 3.32Å; V218-S220 PolarHBondContact O-N 2.64Å; V218-M221 PolarHBondContact O-N 3.25Å; V218-V222 HydrophobicContact CG1-CG2 4.44Å; V218-V222 WeakPolarHBondContact O-CG2 3.43Å; V218-V222 PolarHBondContact O-N 3.02Å
219	M	94.9	Very high	90.4	Very high	60 Å²	60	45.8 Å²	45.8	30%	0.296	26%	0.258	S	S	.	.	H	α-helix	trans	-66.8	-32.9	178.8	-81.7	-53.5	-60.1	0	0	113.1	A155 V159 A215 A216 V222 T223	A155-M219 HydrophobicContact CB-CB 4.5Å; A155-M219 HydrophobicContact CB-CG 3.77Å; A155-M219 WeakPolarHBondContact O-CB 3.43Å; V159-M219 HydrophobicContact CG2-CE 3.58Å; A215-M219 WeakPolarHBondContact O-CB 3.31Å; A215-M219 PolarHBondContact O-N 3.47Å; A216-M219 PolarHBondContact O-N 2.85Å; M219-V222 PolarHBondContact O-N 3.21Å; M219-V222 HydrophobicContact SD-CB 4.47Å; M219-T223 VanDerWaalsContact O-CB 3.3Å; M219-T223 WeakPolarHBondContact O-CB 3.42Å; M219-T223 PolarHBondContact O-N 3.25Å; M219-T223 PolarHBondContact O-OG1 2.66Å
220	S	93.8	Very high	88.9	Confident	0 Å²	0	49.1 Å²	49.1	0%	0	28%	0.282	C	S	.	.	H	α-helix	trans	-61.1	-45.9	174.1	-171.1	0	0	0	0	111.8	I7 G158 G162 A216 P217 V218 T223 Y224	I7-S220 WeakPolarHBondContact CD1-OG 3.29Å; G158-S220 WeakPolarHBondContact O-CA 3.04Å; G158-S220 WeakPolarHBondContact O-CB 3.35Å; G158-S220 PolarHBondContact O-N 2.66Å; G162-S220 WeakPolarHBondContact CA-O 3.12Å; G162-S220 PolarHBondContact N-OG 3.2Å; A216-S220 VanDerWaalsContact O-CB 3.24Å; A216-S220 WeakPolarHBondContact O-CB 3.46Å; A216-S220 PolarHBondContact O-N 2.62Å; P217-S220 PolarHBondContact O-N 3.16Å; V218-S220 VanDerWaalsContact C-N 3.32Å; V218-S220 PolarHBondContact O-N 2.64Å; S220-T223 PolarHBondContact O-N 3.15Å; S220-Y224 WeakPolarHBondContact O-CB 3.29Å; S220-Y224 PolarHBondContact O-N 2.87Å
221	M	93.2	Very high	86.8	Confident	40 Å²	40	50.1 Å²	50.1	20%	0.197	30%	0.296	C	S	.	.	H	α-helix	trans	-64.3	-45.5	176.3	-169.2	58.6	59.7	0	0	112.3	F4 I7 C8 P217 V218 T223 Y224 L225	F4-M221 HydrophobicContact CD2-SD 4.3Å; F4-M221 HydrophobicContact CE2-CE 4.46Å; F4-M221 HydrophobicContact CE2-SD 3.68Å; I7-M221 HydrophobicContact CG2-CE 4.05Å; I7-M221 HydrophobicContact CG2-SD 4.46Å; C8-M221 HydrophobicContact CB-CE 4.43Å; C8-M221 WeakPolarHBondContact SG-CE 3.41Å; P217-M221 PolarHBondContact O-N 3.44Å; P217-M221 VanDerWaalsContact O-N 3.12Å; V218-M221 PolarHBondContact O-N 3.25Å; M221-T223 PolarHBondContact O-N 3.35Å; M221-Y224 PolarHBondContact O-N 3.29Å; M221-L225 HydrophobicContact CG-CD1 4Å; M221-L225 HydrophobicContact CG-CG 4.47Å; M221-L225 WeakPolarHBondContact O-CB 3.48Å; M221-L225 VanDerWaalsContact O-CG 3.27Å; M221-L225 WeakPolarHBondContact O-CG 3.31Å; M221-L225 PolarHBondContact O-N 2.86Å; M221-L225 HydrophobicContact SD-CD1 4.23Å; M221-L225 HydrophobicContact SD-CG 4.28Å
222	V	93.1	Very high	84.9	Confident	81 Å²	81	54.7 Å²	54.7	49%	0.491	31%	0.309	S	S	.	.	H	α-helix	trans	-60.4	-46.9	178.5	169.1	0	0	0	0	110.8	V218 M219 L225 G226	V218-V222 HydrophobicContact CG1-CG2 4.44Å; V218-V222 WeakPolarHBondContact O-CG2 3.43Å; V218-V222 PolarHBondContact O-N 3.02Å; M219-V222 PolarHBondContact O-N 3.21Å; M219-V222 HydrophobicContact SD-CB 4.47Å; V222-L225 PolarHBondContact O-N 3.38Å; V222-G226 PolarHBondContact O-N 3.46Å
223	T	90.9	Very high	82.7	Confident	21 Å²	21	62.6 Å²	62.6	13%	0.129	35%	0.346	C	S	.	.	H	α-helix	trans	-63.3	-48.2	179.3	-63.1	0	0	0	0	111.2	V159 A163 M219 S220 M221 L225 G226 L227	V159-T223 HydrophobicContact CG1-CG2 4.37Å; A163-T223 HydrophobicContact CB-CG2 4.42Å; M219-T223 VanDerWaalsContact O-CB 3.3Å; M219-T223 WeakPolarHBondContact O-CB 3.42Å; M219-T223 PolarHBondContact O-N 3.25Å; M219-T223 PolarHBondContact O-OG1 2.66Å; S220-T223 PolarHBondContact O-N 3.15Å; M221-T223 PolarHBondContact O-N 3.35Å; T223-L225 PolarHBondContact O-N 2.9Å; T223-G226 PolarHBondContact O-N 3.42Å; T223-L227 HydrophobicContact CG2-CD1 3.8Å; T223-L227 HydrophobicContact CG2-CG 4.31Å; T223-L227 WeakPolarHBondContact O-CB 3.44Å; T223-L227 VanDerWaalsContact O-CG 3.31Å; T223-L227 WeakPolarHBondContact O-CG 3.49Å; T223-L227 PolarHBondContact O-N 2.97Å
224	Y	89	Confident	80.4	Confident	24 Å²	24	66.5 Å²	66.5	9%	0.094	38%	0.378	C	S	.	.	H	α-helix	trans	-57.8	-47	177.4	174.2	-96.3	0	0	0	112.4	D3 F4 I7 A165 S220 M221 G226 S228	D3-Y224 HydrophobicContact CB-CE2 4.21Å; D3-Y224 VanDerWaalsContact CB-OH 3.32Å; D3-Y224 WeakPolarHBondContact CB-OH 3.41Å; F4-Y224 HydrophobicContact CB-CE1 4.23Å; F4-Y224 HydrophobicContact CD2-CD1 4.42Å; F4-Y224 AromaticContact CD2-CE1 3.93Å; F4-Y224 HydrophobicContact CD2-CE1 3.93Å; F4-Y224 PolarHBondContact N-OH 3.42Å; I7-Y224 HydrophobicContact CD1-CD1 4.37Å; I7-Y224 HydrophobicContact CD1-CD2 4.01Å; I7-Y224 HydrophobicContact CD1-CG 3.64Å; I7-Y224 HydrophobicContact CG2-CD1 4.05Å; I7-Y224 HydrophobicContact CG2-CE1 4.27Å; I7-Y224 HydrophobicContact CG2-CG 4.2Å; A165-Y224 HydrophobicContact CB-CD2 3.93Å; A165-Y224 HydrophobicContact CB-CE2 4.5Å; A165-Y224 WeakPolarHBondContact O-CE2 3.4Å; S220-Y224 WeakPolarHBondContact O-CB 3.29Å; S220-Y224 PolarHBondContact O-N 2.87Å; M221-Y224 PolarHBondContact O-N 3.29Å; Y224-G226 PolarHBondContact O-N 3.35Å; Y224-S228 WeakPolarHBondContact O-CB 3.26Å; Y224-S228 PolarHBondContact O-N 3.01Å
225	L	89.1	Confident	78.1	Confident	66 Å²	66	67.6 Å²	67.6	35%	0.346	38%	0.384	S	S	.	.	H	α-helix	trans	-68.2	-34.7	178.7	-68.3	175.8	0	0	0	112.8	F4 M221 V222 T223 K229	F4-L225 HydrophobicContact CD2-CD2 4.41Å; F4-L225 HydrophobicContact CE2-CD2 4.2Å; M221-L225 HydrophobicContact CG-CD1 4Å; M221-L225 HydrophobicContact CG-CG 4.47Å; M221-L225 WeakPolarHBondContact O-CB 3.48Å; M221-L225 VanDerWaalsContact O-CG 3.27Å; M221-L225 WeakPolarHBondContact O-CG 3.31Å; M221-L225 PolarHBondContact O-N 2.86Å; M221-L225 HydrophobicContact SD-CD1 4.23Å; M221-L225 HydrophobicContact SD-CG 4.28Å; V222-L225 PolarHBondContact O-N 3.38Å; T223-L225 PolarHBondContact O-N 2.9Å; L225-K229 WeakPolarHBondContact O-CG 3.4Å; L225-K229 PolarHBondContact O-N 2.95Å
226	G	85.5	Confident	75.7	Confident	39 Å²	39	72 Å²	72	40%	0.402	41%	0.414	S	S	.	.	H	α-helix	trans	-66.6	-44.9	177	0	0	0	0	0	112.1	V222 T223 Y224 K229 S230	V222-G226 PolarHBondContact O-N 3.46Å; T223-G226 PolarHBondContact O-N 3.42Å; Y224-G226 PolarHBondContact O-N 3.35Å; G226-K229 PolarHBondContact O-N 3Å; G226-S230 PolarHBondContact O-N 3.19Å
227	L	81.5	Confident	73.6	Confident	42 Å²	42	80.6 Å²	80.6	22%	0.22	45%	0.454	C	S	.	.	H	α-helix	trans	-74.1	-29.6	177.9	-62.1	179	0	0	0	112.7	A163 S166 T223 K229 S230 L235	A163-L227 HydrophobicContact CB-CD1 4.31Å; S166-L227 WeakPolarHBondContact OG-CD1 3.3Å; T223-L227 HydrophobicContact CG2-CD1 3.8Å; T223-L227 HydrophobicContact CG2-CG 4.31Å; T223-L227 WeakPolarHBondContact O-CB 3.44Å; T223-L227 VanDerWaalsContact O-CG 3.31Å; T223-L227 WeakPolarHBondContact O-CG 3.49Å; T223-L227 PolarHBondContact O-N 2.97Å; L227-K229 VanDerWaalsContact C-N 3.26Å; L227-K229 PolarHBondContact O-N 3.46Å; L227-S230 VanDerWaalsContact O-O 3.14Å; L227-L235 HydrophobicContact CD1-CD1 4.34Å; L227-L235 HydrophobicContact CD2-CB 4.48Å; L227-L235 HydrophobicContact CD2-CD1 3.39Å; L227-L235 HydrophobicContact CD2-CG 3.93Å; L227-L235 HydrophobicContact CG-CD1 4.48Å
228	S	72.3	Confident	71.5	Confident	82 Å²	82	83.8 Å²	83.8	57%	0.573	47%	0.473	S	S	*	.	H	α-helix	trans	-70.5	-19.8	173.9	-178.3	0	0	0	0	113.4	Y224	Y224-S228 WeakPolarHBondContact O-CB 3.26Å; Y224-S228 PolarHBondContact O-N 3.01Å
229	K	67.6	Low	70.4	Confident	177 Å²	177	81.3 Å²	81.3	77%	0.77	46%	0.457	S	S	*	.	H	α-helix	trans	-99.7	-29.8	-177.7	-75.1	179.2	-179	-179.9	0	114.3	L225 G226 L227	L225-K229 WeakPolarHBondContact O-CG 3.4Å; L225-K229 PolarHBondContact O-N 2.95Å; G226-K229 PolarHBondContact O-N 3Å; L227-K229 VanDerWaalsContact C-N 3.26Å; L227-K229 PolarHBondContact O-N 3.46Å
230	S	61.1	Low	69.7	Low	71 Å²	71	79.7 Å²	79.7	50%	0.497	45%	0.453	S	S	.	.	S	Bend	trans	-78	134.5	168.4	-77	0	0	0	0	109	G226 L227 K232	G226-S230 PolarHBondContact O-N 3.19Å; L227-S230 VanDerWaalsContact O-O 3.14Å; S230-K232 PolarHBondContact O-N 2.96Å
231	S	52.1	Low	69.3	Low	99 Å²	99	79.9 Å²	79.9	69%	0.692	45%	0.454	S	S	*	.			trans	-46.8	131.1	166.1	-65	0	0	0	0	108.7	E233	S231-E233 PolarHBondContact O-N 3.42Å
232	K	51.8	Low	69	Low	174 Å²	174	78 Å²	78	76%	0.757	45%	0.445	S	S	*	.	T	Hydrogen-bonded Turn	trans	-52.6	3.1	-168.5	-64.9	179.2	173.8	-173.4	0	116.6	S230	S230-K232 PolarHBondContact O-N 2.96Å
233	E	48.6	Very low	68.8	Low	167 Å²	167	75.8 Å²	75.8	78%	0.78	43%	0.432	S	S	*	.	T	Hydrogen-bonded Turn	trans	-85.9	-26	-170.6	-66.9	173.9	170.6	0	0	113.7	S231 L235	S231-E233 PolarHBondContact O-N 3.42Å; E233-L235 PolarHBondContact O-N 3.47Å
234	A	45.9	Very low	68.7	Low	83 Å²	83	75.4 Å²	75.4	69%	0.686	43%	0.431	S	S	*	.	S	Bend	trans	-76	-24	-170.9	0	0	0	0	0	115.2
235	L	47.7	Very low	68.8	Low	88 Å²	88	74.4 Å²	74.4	46%	0.461	43%	0.427	S	S	.	.	S	Bend	trans	-118.8	5.3	176.5	-64.6	-161.6	0	0	0	113.9	L227 E233 E237 V238	L227-L235 HydrophobicContact CD1-CD1 4.34Å; L227-L235 HydrophobicContact CD2-CB 4.48Å; L227-L235 HydrophobicContact CD2-CD1 3.39Å; L227-L235 HydrophobicContact CD2-CG 3.93Å; L227-L235 HydrophobicContact CG-CD1 4.48Å; E233-L235 PolarHBondContact O-N 3.47Å; L235-E237 PolarHBondContact O-N 2.96Å; L235-V238 PolarHBondContact O-N 3.45Å
236	S	46.4	Very low	69	Low	104 Å²	104	71.3 Å²	71.3	73%	0.727	41%	0.411	S	S	*	.	T	Hydrogen-bonded Turn	trans	-61.4	-10	174.8	176.6	0	0	0	0	113.3
237	E	49	Very low	69.3	Low	182 Å²	182	71.8 Å²	71.8	85%	0.85	40%	0.402	S	S	*	.	T	Hydrogen-bonded Turn	trans	-104.1	-6.6	-173.7	-148.3	180	-179.8	0	0	113.8	L235	L235-E237 PolarHBondContact O-N 2.96Å
238	V	51.5	Low	69.7	Low	78 Å²	78	69.8 Å²	69.8	47%	0.473	39%	0.391	S	S	.	.	S	Bend	trans	-133.6	126.3	-178	-170.9	0	0	0	0	109.7	L235 A240 V243	L235-V238 PolarHBondContact O-N 3.45Å; V238-A240 PolarHBondContact O-N 2.95Å; V238-V243 HydrophobicContact CG1-CG2 4.39Å
239	N	73.8	Confident	70.6	Confident	29 Å²	29	65.9 Å²	65.9	16%	0.155	36%	0.364	C	S	.	.			trans	-55.6	64.7	170.7	-57.8	4.5	0	0	0	112.1	L62 D65 I66 T241 G242 V243	L62-N239 HydrophobicContact CD1-CB 3.45Å; L62-N239 VanDerWaalsContact CD1-CB 3.45Å; L62-N239 VanDerWaalsContact CD1-ND2 3.31Å; L62-N239 WeakPolarHBondContact CD1-ND2 3.41Å; L62-N239 PolarHBondContact O-ND2 3.48Å; D65-N239 HydrophobicContact CB-CB 4.25Å; D65-N239 WeakPolarHBondContact OD2-CA 3.46Å; I66-N239 WeakPolarHBondContact CD1-ND2 3.2Å; I66-N239 WeakPolarHBondContact CG1-ND2 3.44Å; N239-T241 PolarHBondContact O-N 3.48Å; N239-G242 PolarHBondContact O-N 3.39Å; N239-V243 WeakPolarHBondContact O-CB 3.41Å; N239-V243 WeakPolarHBondContact O-CG2 3.5Å; N239-V243 PolarHBondContact O-N 3.45Å
240	A	79.6	Confident	71.7	Confident	26 Å²	26	57.6 Å²	57.6	22%	0.215	33%	0.328	C	S	.	.	H	α-helix	trans	-64.5	-33.7	-164.4	0	0	0	0	0	111.2	A163 V238 A244	A163-A240 HydrophobicContact CB-CB 4.39Å; V238-A240 PolarHBondContact O-N 2.95Å; A240-A244 WeakPolarHBondContact O-CB 3.41Å; A240-A244 PolarHBondContact O-N 2.98Å
241	T	85.1	Confident	73.1	Confident	4 Å²	4	54.2 Å²	54.2	3%	0.025	31%	0.305	C	S	.	.	H	α-helix	trans	-63.8	-56.4	176.4	-52.9	0	0	0	0	111.2	A61 A164 V176 N239 A244 M245	A61-T241 HydrophobicContact CB-CG2 4.41Å; A164-T241 HydrophobicContact CB-CG2 4.02Å; A164-T241 PolarHBondContact N-OG1 3.44Å; V176-T241 HydrophobicContact CG1-CG2 4.35Å; V176-T241 HydrophobicContact CG2-CG2 3.85Å; N239-T241 PolarHBondContact O-N 3.48Å; T241-A244 PolarHBondContact O-N 2.87Å; T241-M245 HydrophobicContact CG2-CE 3.89Å; T241-M245 WeakPolarHBondContact O-CG 3.3Å; T241-M245 PolarHBondContact O-N 3.49Å
242	G	86.9	Confident	74.7	Confident	0 Å²	0	49.5 Å²	49.5	0%	0	27%	0.272	C	S	.	.	H	α-helix	trans	-62.9	-44	179.6	0	0	0	0	0	112.5	G58 N239 M245 L246	G58-G242 WeakPolarHBondContact O-CA 3.03Å; N239-G242 PolarHBondContact O-N 3.39Å; G242-M245 PolarHBondContact O-N 3.42Å; G242-L246 WeakPolarHBondContact O-CB 3.3Å; G242-L246 WeakPolarHBondContact O-CD1 3.49Å; G242-L246 VanDerWaalsContact O-CG 3.29Å; G242-L246 WeakPolarHBondContact O-CG 3.33Å; G242-L246 PolarHBondContact O-N 2.97Å
243	V	89.5	Confident	76.4	Confident	35 Å²	35	42.9 Å²	42.9	21%	0.212	25%	0.245	C	C	.	.	H	α-helix	trans	-61.4	-44.5	175.7	168.7	0	0	0	0	111.5	L62 V238 N239 L246 F247	L62-V243 HydrophobicContact CD1-CG2 3.95Å; V238-V243 HydrophobicContact CG1-CG2 4.39Å; N239-V243 WeakPolarHBondContact O-CB 3.41Å; N239-V243 WeakPolarHBondContact O-CG2 3.5Å; N239-V243 PolarHBondContact O-N 3.45Å; V243-L246 PolarHBondContact O-N 3Å; V243-F247 VanDerWaalsContact O-CB 3.24Å; V243-F247 WeakPolarHBondContact O-CB 3.44Å; V243-F247 PolarHBondContact O-N 3.08Å
244	A	89.6	Confident	78.3	Confident	13 Å²	13	35.3 Å²	35.3	11%	0.107	21%	0.209	C	C	.	.	H	α-helix	trans	-65.3	-39.5	178.1	0	0	0	0	0	112.2	V159 A160 A240 T241 S248	V159-A244 HydrophobicContact CG1-CB 4.13Å; A160-A244 HydrophobicContact CB-CB 3.96Å; A240-A244 WeakPolarHBondContact O-CB 3.41Å; A240-A244 PolarHBondContact O-N 2.98Å; T241-A244 PolarHBondContact O-N 2.87Å; A244-S248 VanDerWaalsContact O-CB 3.3Å; A244-S248 WeakPolarHBondContact O-CB 3.47Å; A244-S248 PolarHBondContact O-N 3.22Å
245	M	89.8	Confident	80.1	Confident	4 Å²	4	31.4 Å²	31.4	2%	0.02	18%	0.177	C	C	.	.	H	α-helix	trans	-66.1	-43	175	-71.8	-168.7	-68.9	0	0	112.2	I54 A61 A160 V176 T241 G242 S248 A249	I54-M245 WeakPolarHBondContact CG2-O 2.99Å; A61-M245 HydrophobicContact CB-CE 3.21Å; A160-M245 HydrophobicContact CB-CG 3.52Å; V176-M245 HydrophobicContact CG1-SD 4.1Å; V176-M245 HydrophobicContact CG2-CE 4.25Å; T241-M245 HydrophobicContact CG2-CE 3.89Å; T241-M245 WeakPolarHBondContact O-CG 3.3Å; T241-M245 PolarHBondContact O-N 3.49Å; G242-M245 PolarHBondContact O-N 3.42Å; M245-S248 CarbonylContact O-C 3.42Å; M245-S248 WeakPolarHBondContact O-CA 3.49Å; M245-S248 VanDerWaalsContact O-CB 3.29Å; M245-S248 WeakPolarHBondContact O-CB 3.38Å; M245-S248 PolarHBondContact O-N 2.96Å; M245-A249 PolarHBondContact O-N 3.2Å
246	L	93	Very high	81.7	Confident	0 Å²	0	27.3 Å²	27.3	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-67.9	-39.5	177.3	-71.7	164.3	0	0	0	112.3	V55 V59 L62 I106 L110 G242 V243 S248 A249 G250	V55-L246 HydrophobicContact CG1-CD2 4.47Å; V59-L246 HydrophobicContact CG2-CD2 4.03Å; L62-L246 HydrophobicContact CD2-CD1 4.14Å; I106-L246 HydrophobicContact CB-CD1 4.42Å; I106-L246 HydrophobicContact CG1-CD1 4.13Å; I106-L246 HydrophobicContact CG2-CD1 4.49Å; I106-L246 HydrophobicContact CG2-CD2 4.14Å; L110-L246 HydrophobicContact CD1-CD2 4.48Å; L110-L246 HydrophobicContact CD2-CD2 4.34Å; L110-L246 VanDerWaalsContact CD2-O 3.26Å; L110-L246 WeakPolarHBondContact CD2-O 3.45Å; L110-L246 HydrophobicContact CG-CD2 4.27Å; G242-L246 WeakPolarHBondContact O-CB 3.3Å; G242-L246 WeakPolarHBondContact O-CD1 3.49Å; G242-L246 VanDerWaalsContact O-CG 3.29Å; G242-L246 WeakPolarHBondContact O-CG 3.33Å; G242-L246 PolarHBondContact O-N 2.97Å; V243-L246 PolarHBondContact O-N 3Å; L246-S248 VanDerWaalsContact C-N 3.31Å; L246-A249 WeakPolarHBondContact O-CB 3.08Å; L246-A249 PolarHBondContact O-N 3.11Å; L246-G250 PolarHBondContact O-N 3.38Å
247	F	92.9	Very high	83.6	Confident	50 Å²	50	25 Å²	25	22%	0.219	14%	0.137	C	C	.	.	H	α-helix	trans	-57.8	-47	168.9	177.8	-88.7	0	0	0	110.4	S109 L112 G113 F116 A156 V243 A249 G250 T251	S109-F247 WeakPolarHBondContact O-CA 3.34Å; L112-F247 HydrophobicContact CB-CD2 4.31Å; L112-F247 HydrophobicContact CB-CE2 4.5Å; G113-F247 VanDerWaalsContact CA-CD2 3.45Å; G113-F247 WeakPolarHBondContact CA-O 3.31Å; F116-F247 HydrophobicContact CB-CE2 3.91Å; F116-F247 HydrophobicContact CB-CZ 3.77Å; F116-F247 HydrophobicContact CD1-CE1 4.37Å; F116-F247 AromaticContact CD1-CZ 3.69Å; F116-F247 HydrophobicContact CD1-CZ 3.69Å; F116-F247 HydrophobicContact CD2-CZ 4.37Å; F116-F247 HydrophobicContact CE1-CZ 4.39Å; F116-F247 HydrophobicContact CG-CE2 4.25Å; F116-F247 AromaticContact CG-CZ 3.67Å; F116-F247 HydrophobicContact CG-CZ 3.67Å; A156-F247 HydrophobicContact CB-CD1 4.04Å; A156-F247 HydrophobicContact CB-CE1 4.42Å; V243-F247 VanDerWaalsContact O-CB 3.24Å; V243-F247 WeakPolarHBondContact O-CB 3.44Å; V243-F247 PolarHBondContact O-N 3.08Å; F247-A249 PolarHBondContact O-N 3.14Å; F247-G250 PolarHBondContact O-N 2.89Å; F247-G250 VanDerWaalsContact O-N 3.13Å; F247-T251 HydrophobicContact CD1-CG2 4.04Å; F247-T251 HydrophobicContact CE1-CG2 3.7Å; F247-T251 HydrophobicContact CZ-CG2 4.21Å; F247-T251 WeakPolarHBondContact O-CG2 2.9Å; F247-T251 PolarHBondContact O-N 3.39Å
248	S	89.8	Confident	85.1	Confident	0 Å²	0	19.2 Å²	19.2	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-57.7	-44.7	175.8	-166.6	0	0	0	0	112.2	H153 D157 A244 M245 L246 G250 T251 F252	H153-S248 PolarHBondContact CE1-OG 3.01Å; H153-S248 PolarHBondContact ND1-O 3.32Å; H153-S248 PolarHBondContact ND1-OG 3.03Å; H153-S248 PolarHBondContact O-OG 3.36Å; D157-S248 WeakPolarHBondContact OD1-CB 3.15Å; D157-S248 PolarHBondContact OD1-OG 3.47Å; A244-S248 VanDerWaalsContact O-CB 3.3Å; A244-S248 WeakPolarHBondContact O-CB 3.47Å; A244-S248 PolarHBondContact O-N 3.22Å; M245-S248 CarbonylContact O-C 3.42Å; M245-S248 WeakPolarHBondContact O-CA 3.49Å; M245-S248 VanDerWaalsContact O-CB 3.29Å; M245-S248 WeakPolarHBondContact O-CB 3.38Å; M245-S248 PolarHBondContact O-N 2.96Å; L246-S248 VanDerWaalsContact C-N 3.31Å; S248-G250 VanDerWaalsContact C-N 3.31Å; S248-G250 PolarHBondContact O-N 3.36Å; S248-T251 PolarHBondContact O-N 3.07Å; S248-T251 VanDerWaalsContact O-N 3.16Å; S248-T251 PolarHBondContact O-OG1 2.92Å; S248-F252 PolarHBondContact O-N 2.97Å
249	A	90.7	Very high	86.2	Confident	0 Å²	0	16.6 Å²	16.6	0%	0	10%	0.097	C	C	.	.	H	α-helix	trans	-57.6	-43.4	174.7	0	0	0	0	0	112.2	I54 V55 L110 M245 L246 F247 F252 L253	I54-A249 HydrophobicContact CB-CB 3.88Å; I54-A249 HydrophobicContact CG2-CB 3.63Å; V55-A249 HydrophobicContact CG2-CB 3.77Å; L110-A249 HydrophobicContact CD2-CB 3.6Å; M245-A249 PolarHBondContact O-N 3.2Å; L246-A249 WeakPolarHBondContact O-CB 3.08Å; L246-A249 PolarHBondContact O-N 3.11Å; F247-A249 PolarHBondContact O-N 3.14Å; A249-F252 PolarHBondContact O-N 3.07Å; A249-L253 WeakPolarHBondContact O-CB 3.37Å; A249-L253 WeakPolarHBondContact O-CD1 3.4Å; A249-L253 PolarHBondContact O-N 3.25Å
250	G	91.8	Very high	86.2	Confident	2 Å²	2	15.3 Å²	15.3	2%	0.021	9%	0.09	C	C	.	.	H	α-helix	trans	-59.9	-45	175.2	0	0	0	0	0	112.9	L110 F114 L246 F247 S248 F252 L253 Y254	L110-G250 VanDerWaalsContact O-CA 3.31Å; L110-G250 WeakPolarHBondContact O-CA 3.48Å; F114-G250 WeakPolarHBondContact CA-O 3.48Å; L246-G250 PolarHBondContact O-N 3.38Å; F247-G250 PolarHBondContact O-N 2.89Å; F247-G250 VanDerWaalsContact O-N 3.13Å; S248-G250 VanDerWaalsContact C-N 3.31Å; S248-G250 PolarHBondContact O-N 3.36Å; G250-F252 VanDerWaalsContact C-N 3.28Å; G250-F252 PolarHBondContact O-N 3.18Å; G250-L253 PolarHBondContact O-N 2.83Å; G250-Y254 PolarHBondContact O-N 3.36Å
251	T	89.5	Confident	85.9	Confident	0 Å²	0	17.2 Å²	17.2	0%	0	10%	0.096	C	C	.	.	H	α-helix	trans	-59.5	-41.2	175.6	68.2	0	0	0	0	111.7	G113 M117 V152 H153 F247 S248 Y254 V255	G113-T251 WeakPolarHBondContact O-CG2 3.37Å; M117-T251 HydrophobicContact CG-CG2 3.74Å; V152-T251 HydrophobicContact CG1-CG2 4.44Å; H153-T251 WeakPolarHBondContact CA-OG1 3.33Å; H153-T251 WeakPolarHBondContact CB-OG1 3.49Å; H153-T251 PolarHBondContact ND1-OG1 3.43Å; F247-T251 HydrophobicContact CD1-CG2 4.04Å; F247-T251 HydrophobicContact CE1-CG2 3.7Å; F247-T251 HydrophobicContact CZ-CG2 4.21Å; F247-T251 WeakPolarHBondContact O-CG2 2.9Å; F247-T251 PolarHBondContact O-N 3.39Å; S248-T251 PolarHBondContact O-N 3.07Å; S248-T251 VanDerWaalsContact O-N 3.16Å; S248-T251 PolarHBondContact O-OG1 2.92Å; T251-Y254 WeakPolarHBondContact O-CB 3.33Å; T251-Y254 PolarHBondContact O-N 2.99Å; T251-V255 PolarHBondContact O-N 2.96Å
252	F	85.3	Confident	85.3	Confident	0 Å²	0	20.4 Å²	20.4	0%	0	12%	0.117	C	C	.	.	H	α-helix	trans	-74	-38.8	-175.8	-158.7	-133.5	0	0	0	112.4	L46 T49 A50 I54 L150 H153 A187 S248 A249 G250 Y254 V255 A256	L46-F252 HydrophobicContact CB-CE1 4.09Å; L46-F252 HydrophobicContact CB-CE2 4.38Å; L46-F252 HydrophobicContact CB-CZ 3.85Å; L46-F252 HydrophobicContact CD2-CE1 4.28Å; L46-F252 HydrophobicContact CD2-CE2 3.69Å; L46-F252 HydrophobicContact CD2-CZ 3.29Å; L46-F252 HydrophobicContact CG-CE2 4.46Å; L46-F252 HydrophobicContact CG-CZ 4.1Å; L46-F252 WeakPolarHBondContact O-CD1 3.01Å; L46-F252 WeakPolarHBondContact O-CE1 3.36Å; T49-F252 HydrophobicContact CG2-CE1 3.95Å; A50-F252 HydrophobicContact CB-CB 4.49Å; A50-F252 HydrophobicContact CB-CD1 3.79Å; I54-F252 HydrophobicContact CD1-CD1 3.86Å; I54-F252 HydrophobicContact CD1-CE1 4.38Å; I54-F252 HydrophobicContact CD1-CG 4.48Å; L150-F252 HydrophobicContact CD2-CD2 3.8Å; L150-F252 HydrophobicContact CD2-CE2 3.54Å; H153-F252 AromaticContact CD2-CD2 3.44Å; H153-F252 VanDerWaalsContact CD2-CD2 3.44Å; H153-F252 WeakPolarHBondContact CD2-CD2 3.36Å; H153-F252 AromaticContact CD2-CE2 3.8Å; H153-F252 AromaticContact CE1-CD2 3.87Å; H153-F252 AromaticContact CE1-CG 3.77Å; H153-F252 AromaticContact CG-CD2 3.83Å; H153-F252 AromaticContact NE2-CD2 3.45Å; H153-F252 WeakPolarHBondContact NE2-CD2 3.3Å; H153-F252 AromaticContact NE2-CE2 3.71Å; H153-F252 AromaticContact NE2-CG 3.77Å; A187-F252 HydrophobicContact CB-CE2 3.93Å; A187-F252 HydrophobicContact CB-CZ 3.52Å; S248-F252 PolarHBondContact O-N 2.97Å; A249-F252 PolarHBondContact O-N 3.07Å; G250-F252 VanDerWaalsContact C-N 3.28Å; G250-F252 PolarHBondContact O-N 3.18Å; F252-Y254 VanDerWaalsContact C-N 3.31Å; F252-Y254 PolarHBondContact O-N 2.98Å; F252-V255 PolarHBondContact O-N 3.44Å; F252-A256 WeakPolarHBondContact O-CB 3.45Å; F252-A256 PolarHBondContact O-N 2.93Å
253	L	89	Confident	84.3	Confident	36 Å²	36	23.5 Å²	23.5	19%	0.188	13%	0.131	C	C	.	.	H	α-helix	trans	-57.5	-41.7	171.1	-90.4	149.1	0	0	0	111.9	A50 L51 F114 A249 G250 A256 T257	A50-L253 HydrophobicContact CB-CD1 4.28Å; A50-L253 HydrophobicContact CB-CG 3.85Å; L51-L253 HydrophobicContact CD2-CD1 4.22Å; L51-L253 HydrophobicContact CD2-CD2 4.07Å; L51-L253 HydrophobicContact CG-CD2 4.33Å; F114-L253 HydrophobicContact CD2-CB 4.45Å; A249-L253 WeakPolarHBondContact O-CB 3.37Å; A249-L253 WeakPolarHBondContact O-CD1 3.4Å; A249-L253 PolarHBondContact O-N 3.25Å; G250-L253 PolarHBondContact O-N 2.83Å; L253-A256 PolarHBondContact O-N 3.44Å; L253-T257 WeakPolarHBondContact O-CB 3.4Å; L253-T257 VanDerWaalsContact O-CG2 3.32Å; L253-T257 WeakPolarHBondContact O-CG2 3.27Å; L253-T257 PolarHBondContact O-N 2.85Å; L253-T257 PolarHBondContact O-OG1 3.38Å
254	Y	88.3	Confident	83.2	Confident	7 Å²	7	21.9 Å²	21.9	3%	0.027	12%	0.121	C	C	.	.	H	α-helix	trans	-59.7	-51.6	174.4	-178.2	-92.6	0	0	0	111.6	F114 M117 L118 D121 G250 T251 F252 A256 T257 V258 H259	F114-Y254 HydrophobicContact CD1-CD2 4.01Å; F114-Y254 HydrophobicContact CD2-CD2 4.21Å; F114-Y254 HydrophobicContact CD2-CG 4.5Å; F114-Y254 AromaticContact CE1-CD2 3.65Å; F114-Y254 HydrophobicContact CE1-CD2 3.65Å; F114-Y254 HydrophobicContact CE1-CE2 4.25Å; F114-Y254 AromaticContact CE2-CD2 3.87Å; F114-Y254 HydrophobicContact CE2-CD2 3.87Å; F114-Y254 HydrophobicContact CE2-CG 4.36Å; F114-Y254 HydrophobicContact CG-CD2 4.27Å; F114-Y254 AromaticContact CZ-CD2 3.58Å; F114-Y254 HydrophobicContact CZ-CD2 3.58Å; F114-Y254 HydrophobicContact CZ-CE2 4.34Å; F114-Y254 HydrophobicContact CZ-CG 4.49Å; M117-Y254 HydrophobicContact CB-CD1 3.7Å; M117-Y254 HydrophobicContact CB-CE1 4.45Å; M117-Y254 HydrophobicContact CB-CG 3.85Å; M117-Y254 HydrophobicContact CE-CD1 4.5Å; L118-Y254 VanDerWaalsContact CA-CZ 3.5Å; L118-Y254 HydrophobicContact CB-CD2 4.06Å; L118-Y254 HydrophobicContact CB-CE2 3.5Å; L118-Y254 VanDerWaalsContact CB-CE2 3.5Å; L118-Y254 HydrophobicContact CD1-CE2 4.09Å; L118-Y254 HydrophobicContact CG-CE2 3.82Å; D121-Y254 HydrophobicContact CB-CE1 3.97Å; D121-Y254 PolarHBondContact OD2-OH 3.48Å; G250-Y254 PolarHBondContact O-N 3.36Å; T251-Y254 WeakPolarHBondContact O-CB 3.33Å; T251-Y254 PolarHBondContact O-N 2.99Å; F252-Y254 VanDerWaalsContact C-N 3.31Å; F252-Y254 PolarHBondContact O-N 2.98Å; Y254-A256 VanDerWaalsContact C-N 3.34Å; Y254-A256 PolarHBondContact O-N 3.25Å; Y254-T257 PolarHBondContact O-N 2.83Å; Y254-T257 PolarHBondContact O-OG1 2.63Å; Y254-V258 HydrophobicContact CD1-CB 4.49Å; Y254-V258 HydrophobicContact CD2-CB 4.34Å; Y254-V258 HydrophobicContact CD2-CG2 3.73Å; Y254-V258 HydrophobicContact CE1-CB 4.25Å; Y254-V258 HydrophobicContact CE1-CG1 4.32Å; Y254-V258 HydrophobicContact CE2-CB 4.05Å; Y254-V258 HydrophobicContact CE2-CG1 4.13Å; Y254-V258 HydrophobicContact CE2-CG2 3.61Å; Y254-V258 HydrophobicContact CG-CG2 4.27Å; Y254-V258 VanDerWaalsContact O-CB 3.29Å; Y254-V258 WeakPolarHBondContact O-CB 3.4Å; Y254-V258 PolarHBondContact O-N 2.86Å; Y254-H259 AromaticContact CE1-CE1 3.6Å; Y254-H259 AromaticContact CE1-ND1 3.73Å
255	V	82.8	Confident	81.7	Confident	1 Å²	1	22.5 Å²	22.5	1%	0.006	13%	0.129	C	C	.	.	I	π-helix	trans	-58.9	-46.8	180	175.6	0	0	0	0	110.9	M117 T146 L150 T251 F252 T257 H259 V260	M117-V255 HydrophobicContact CE-CG2 4.4Å; T146-V255 HydrophobicContact CG2-CG1 4.2Å; L150-V255 HydrophobicContact CD1-CG1 4.29Å; L150-V255 HydrophobicContact CD2-CG1 3.99Å; L150-V255 HydrophobicContact CG-CG1 3.99Å; T251-V255 PolarHBondContact O-N 2.96Å; F252-V255 PolarHBondContact O-N 3.44Å; V255-T257 PolarHBondContact O-N 3.46Å; V255-H259 WeakPolarHBondContact O-CB 3.35Å; V255-H259 PolarHBondContact O-N 3.43Å; V255-H259 VanDerWaalsContact O-N 3.13Å; V255-V260 HydrophobicContact CG1-CG2 4.14Å; V255-V260 PolarHBondContact O-N 3.46Å; V255-V260 VanDerWaalsContact O-N 3.1Å
256	A	82.2	Confident	80.1	Confident	3 Å²	3	25.3 Å²	25.3	3%	0.025	16%	0.159	C	C	.	.	I	π-helix	trans	-62.5	-44.9	-179.2	0	0	0	0	0	112.4	L46 C47 F252 L253 Y254 L261	L46-A256 HydrophobicContact CB-CB 3.94Å; C47-A256 HydrophobicContact CB-CB 4.36Å; F252-A256 WeakPolarHBondContact O-CB 3.45Å; F252-A256 PolarHBondContact O-N 2.93Å; L253-A256 PolarHBondContact O-N 3.44Å; Y254-A256 VanDerWaalsContact C-N 3.34Å; Y254-A256 PolarHBondContact O-N 3.25Å; A256-L261 WeakPolarHBondContact O-CB 3.4Å; A256-L261 PolarHBondContact O-N 2.81Å
257	T	85.3	Confident	77.9	Confident	55 Å²	55	29.4 Å²	29.4	34%	0.337	18%	0.18	S	C	.	.	I	π-helix	trans	-85.8	-33.6	-171.9	56.8	0	0	0	0	114.1	L253 Y254 V255 P262	L253-T257 WeakPolarHBondContact O-CB 3.4Å; L253-T257 VanDerWaalsContact O-CG2 3.32Å; L253-T257 WeakPolarHBondContact O-CG2 3.27Å; L253-T257 PolarHBondContact O-N 2.85Å; L253-T257 PolarHBondContact O-OG1 3.38Å; Y254-T257 PolarHBondContact O-N 2.83Å; Y254-T257 PolarHBondContact O-OG1 2.63Å; V255-T257 PolarHBondContact O-N 3.46Å; T257-P262 VanDerWaalsContact O-CD 3.26Å; T257-P262 WeakPolarHBondContact O-CD 3.3Å; T257-P262 WeakPolarHBondContact O-CG 3.26Å
258	V	81.2	Confident	75.6	Confident	60 Å²	60	29.1 Å²	29.1	36%	0.364	19%	0.187	S	C	.	.	I	π-helix	trans	-96.9	-34.7	-174	-178.9	0	0	0	0	112.2	F114 Y254 P262	F114-V258 HydrophobicContact CZ-CG2 4.29Å; Y254-V258 HydrophobicContact CD1-CB 4.49Å; Y254-V258 HydrophobicContact CD2-CB 4.34Å; Y254-V258 HydrophobicContact CD2-CG2 3.73Å; Y254-V258 HydrophobicContact CE1-CB 4.25Å; Y254-V258 HydrophobicContact CE1-CG1 4.32Å; Y254-V258 HydrophobicContact CE2-CB 4.05Å; Y254-V258 HydrophobicContact CE2-CG1 4.13Å; Y254-V258 HydrophobicContact CE2-CG2 3.61Å; Y254-V258 HydrophobicContact CG-CG2 4.27Å; Y254-V258 VanDerWaalsContact O-CB 3.29Å; Y254-V258 WeakPolarHBondContact O-CB 3.4Å; Y254-V258 PolarHBondContact O-N 2.86Å; V258-P262 WeakPolarHBondContact O-CG 3.48Å
259	H	74.8	Confident	73.3	Confident	23 Å²	23	36.7 Å²	36.7	11%	0.106	22%	0.222	C	C	.	.	I	π-helix	trans	-103.9	-48	-175.1	-74.7	74.3	0	0	0	113	D121 T146 Y254 V255 E263	D121-H259 VanDerWaalsContact CG-CE1 3.44Å; D121-H259 IonicContact OD1-CE1 3.88Å; D121-H259 IonicContact OD1-NE2 3.63Å; D121-H259 PolarHBondContact OD1-NE2 3.05Å; D121-H259 IonicContact OD2-CE1 3.79Å; D121-H259 PolarHBondContact OD2-CE1 3.31Å; D121-H259 IonicContact OD2-NE2 3.66Å; T146-H259 PolarHBondContact OG1-CD2 2.86Å; Y254-H259 AromaticContact CE1-CE1 3.6Å; Y254-H259 AromaticContact CE1-ND1 3.73Å; V255-H259 WeakPolarHBondContact O-CB 3.35Å; V255-H259 PolarHBondContact O-N 3.43Å; V255-H259 VanDerWaalsContact O-N 3.13Å; H259-E263 VanDerWaalsContact O-CB 3.28Å; H259-E263 WeakPolarHBondContact O-CB 3.31Å
260	V	73.3	Confident	70.9	Confident	2 Å²	2	42 Å²	42	1%	0.012	26%	0.259	C	S	.	.	I	π-helix	trans	-85.2	-47.3	-168.8	-172	0	0	0	0	111.5	A43 L46 F194 V255 V264	A43-V260 HydrophobicContact CB-CB 4.32Å; A43-V260 HydrophobicContact CB-CG1 3.46Å; A43-V260 VanDerWaalsContact CB-CG1 3.46Å; L46-V260 HydrophobicContact CD1-CB 4.34Å; L46-V260 HydrophobicContact CD1-CG1 4.36Å; L46-V260 HydrophobicContact CD1-CG2 3.77Å; F194-V260 HydrophobicContact CD2-CG1 4.23Å; V255-V260 HydrophobicContact CG1-CG2 4.14Å; V255-V260 PolarHBondContact O-N 3.46Å; V255-V260 VanDerWaalsContact O-N 3.1Å; V260-V264 VanDerWaalsContact O-CG2 3.22Å; V260-V264 WeakPolarHBondContact O-CG2 3.41Å; V260-V264 PolarHBondContact O-N 3.18Å
261	L	73.5	Confident	68.4	Low	67 Å²	67	50.2 Å²	50.2	35%	0.351	30%	0.297	S	S	.	.	H	α-helix	trans	-66.2	-43.2	-176.5	-169.3	64.2	0	0	0	113.9	A256 G265 L289	A256-L261 WeakPolarHBondContact O-CB 3.4Å; A256-L261 PolarHBondContact O-N 2.81Å; L261-G265 PolarHBondContact O-N 2.88Å; L261-L289 HydrophobicContact CD1-CD1 3.72Å; L261-L289 HydrophobicContact CD1-CD2 3.82Å; L261-L289 HydrophobicContact CD1-CG 4.46Å
262	P	71.5	Confident	65.8	Low	70 Å²	70	58.3 Å²	58.3	46%	0.455	33%	0.332	S	S	.	.	H	α-helix	trans	-70.3	-38	179.7	-22	37	0	0	0	113.3	T257 V258 V264 G265 G266	T257-P262 VanDerWaalsContact O-CD 3.26Å; T257-P262 WeakPolarHBondContact O-CD 3.3Å; T257-P262 WeakPolarHBondContact O-CG 3.26Å; V258-P262 WeakPolarHBondContact O-CG 3.48Å; P262-V264 VanDerWaalsContact C-N 3.25Å; P262-V264 PolarHBondContact O-N 2.96Å; P262-G265 PolarHBondContact O-N 3.45Å; P262-G265 VanDerWaalsContact O-N 3.15Å; P262-G266 PolarHBondContact O-N 2.9Å
263	E	67.1	Low	63.8	Low	65 Å²	65	64.9 Å²	64.9	30%	0.304	37%	0.374	S	S	.	.	H	α-helix	trans	-61.1	-37.6	179.1	-168.8	72.8	177.4	0	0	110.9	F194 H259 I267	F194-E263 HydrophobicContact CE2-CB 4.23Å; F194-E263 HydrophobicContact CE2-CG 3.99Å; H259-E263 VanDerWaalsContact O-CB 3.28Å; H259-E263 WeakPolarHBondContact O-CB 3.31Å; E263-I267 HydrophobicContact CG-CD1 3.77Å; E263-I267 WeakPolarHBondContact O-CD1 3.38Å; E263-I267 WeakPolarHBondContact O-CG1 3.34Å
264	V	66.1	Low	61.3	Low	1 Å²	1	70.6 Å²	70.6	1%	0.006	40%	0.4	C	S	.	.	H	α-helix	trans	-71	-32.6	177.9	173.4	0	0	0	0	112.7	T39 V40 V260 P262 L281	T39-V264 HydrophobicContact CG2-CG2 3.68Å; V40-V264 HydrophobicContact CB-CG1 4Å; V40-V264 HydrophobicContact CG1-CG1 4.27Å; V40-V264 HydrophobicContact CG2-CG1 3.15Å; V260-V264 VanDerWaalsContact O-CG2 3.22Å; V260-V264 WeakPolarHBondContact O-CG2 3.41Å; V260-V264 PolarHBondContact O-N 3.18Å; P262-V264 VanDerWaalsContact C-N 3.25Å; P262-V264 PolarHBondContact O-N 2.96Å; V264-L281 HydrophobicContact CG1-CD2 4.05Å
265	G	59	Low	59.3	Low	26 Å²	26	75.2 Å²	75.2	27%	0.268	43%	0.434	S	S	.	.	H	α-helix	trans	-82.8	-28.6	177.2	0	0	0	0	0	114.4	L261 P262	L261-G265 PolarHBondContact O-N 2.88Å; P262-G265 PolarHBondContact O-N 3.45Å; P262-G265 VanDerWaalsContact O-N 3.15Å
266	G	54.2	Low	57.3	Low	63 Å²	63	81.9 Å²	81.9	65%	0.649	47%	0.474	S	S	*	.	H	α-helix	trans	-85.5	-19.7	-172.9	0	0	0	0	0	116.1	P262 A268	P262-G266 PolarHBondContact O-N 2.9Å; G266-A268 PolarHBondContact O-N 3.17Å
267	I	48.7	Very low	55.3	Low	87 Å²	87	85.1 Å²	85.1	45%	0.446	51%	0.508	S	S	.	.			trans	-83.7	16.8	-174.2	-61.1	166.7	0	0	0	112.8	E263 H269	E263-I267 HydrophobicContact CG-CD1 3.77Å; E263-I267 WeakPolarHBondContact O-CD1 3.38Å; E263-I267 WeakPolarHBondContact O-CG1 3.34Å; I267-H269 VanDerWaalsContact C-N 3.33Å; I267-H269 PolarHBondContact O-N 3.34Å
268	A	43	Very low	53.4	Low	43 Å²	43	86.7 Å²	86.7	36%	0.355	54%	0.535	S	S	.	.	S	Bend	trans	-77.2	81.9	172.9	0	0	0	0	0	111.4	G266	G266-A268 PolarHBondContact O-N 3.17Å
269	H	41.4	Very low	52.2	Low	160 Å²	160	91.3 Å²	91.3	74%	0.741	55%	0.55	S	S	*	*			trans	88.2	96.2	164.3	-53.9	-72.5	0	0	0	118.9	I267 H271	I267-H269 VanDerWaalsContact C-N 3.33Å; I267-H269 PolarHBondContact O-N 3.34Å; H269-H271 VanDerWaalsContact C-N 3.27Å; H269-H271 PolarHBondContact O-N 3.24Å
270	S	40	Very low	51.8	Low	112 Å²	112	93.4 Å²	93.4	78%	0.783	58%	0.578	S	S	*	*	S	Bend	trans	-84.8	31	165	72.7	0	0	0	0	114.6
271	H	40.3	Very low	52.1	Low	174 Å²	174	95.5 Å²	95.5	81%	0.806	59%	0.589	S	S	*	*	S	Bend	trans	-144	66.1	170.8	-76.6	-64.5	0	0	0	111.6	H269	H269-H271 VanDerWaalsContact C-N 3.27Å; H269-H271 PolarHBondContact O-N 3.24Å
272	K	35.3	Very low	52.7	Low	170 Å²	170	95 Å²	95	74%	0.739	59%	0.591	S	S	*	*			trans	180	131.2	146.8	-104	172	-178.3	-171.6	0	109.8	E274	K272-E274 PolarHBondContact O-N 2.93Å; K272-E274 VanDerWaalsContact O-N 3.11Å
273	P	42.4	Very low	53.5	Low	137 Å²	137	102.9 Å²	102.9	89%	0.89	61%	0.612	S	S	*	*			trans	-80.9	90.9	169.8	33	-26.4	0	0	0	107.3
274	E	37.7	Very low	54.5	Low	157 Å²	157	105.1 Å²	105.1	73%	0.734	63%	0.625	S	S	*	*			trans	-113.3	115.7	164.6	-87.1	-173.4	170.5	0	0	109.9	K272	K272-E274 PolarHBondContact O-N 2.93Å; K272-E274 VanDerWaalsContact O-N 3.11Å
275	S	45.7	Very low	55.6	Low	104 Å²	104	106 Å²	106	73%	0.727	63%	0.629	S	S	*	*			trans	-52.4	140.9	164.1	49.7	0	0	0	0	111.6
276	T	41	Very low	57.1	Low	140 Å²	140	107.8 Å²	107.8	86%	0.859	64%	0.635	S	S	*	*	S	Bend	trans	95	114.3	165.7	69.2	0	0	0	0	118.4
277	G	39.3	Very low	58.9	Low	71 Å²	71	107.4 Å²	107.4	73%	0.732	63%	0.626	S	S	*	*			trans	84.4	104.8	151.6	0	0	0	0	0	116.7	K279	G277-K279 PolarHBondContact O-N 3.3Å
278	G	47	Very low	61	Low	88 Å²	88	104 Å²	104	91%	0.907	61%	0.611	S	S	*	*			trans	-51.4	119.6	178.6	0	0	0	0	0	113.2	G280	G278-G280 PolarHBondContact O-N 2.95Å
279	K	55	Low	63.2	Low	157 Å²	157	103.5 Å²	103.5	68%	0.683	60%	0.602	S	S	*	*			trans	-78.9	105	172.1	-76.2	176	178.2	164.5	0	108.2	G277	G277-K279 PolarHBondContact O-N 3.3Å
280	G	66.6	Low	65.7	Low	68 Å²	68	99.4 Å²	99.4	70%	0.701	59%	0.588	S	S	*	*			trans	-65.7	-179.4	172	0	0	0	0	0	113	G278	G278-G280 PolarHBondContact O-N 2.95Å
281	L	78.7	Confident	68.2	Low	45 Å²	45	98.7 Å²	98.7	24%	0.236	58%	0.575	C	S	.	*			trans	-57.7	139.4	-179.8	-61.7	176.3	0	0	0	111.9	V264 E285 V286 L289	V264-L281 HydrophobicContact CG1-CD2 4.05Å; L281-E285 HydrophobicContact CB-CB 4Å; L281-E285 HydrophobicContact CD2-CB 4.21Å; L281-V286 HydrophobicContact CB-CG2 3.65Å; L281-L289 HydrophobicContact CD1-CD2 3.93Å
282	S	86.6	Confident	70.7	Confident	57 Å²	57	90.4 Å²	90.4	40%	0.399	54%	0.537	S	S	.	.			trans	-63.4	160.8	169.8	69.8	0	0	0	0	111.2	L284 E285 V286	S282-L284 PolarHBondContact O-N 3.29Å; S282-L284 VanDerWaalsContact O-N 3.16Å; S282-E285 VanDerWaalsContact CB-OE2 3.29Å; S282-E285 WeakPolarHBondContact CB-OE2 3.38Å; S282-E285 PolarHBondContact N-OE2 3.25Å; S282-E285 PolarHBondContact O-N 2.95Å; S282-E285 VanDerWaalsContact OG-CG 3.24Å; S282-E285 WeakPolarHBondContact OG-CG 3.41Å; S282-E285 PolarHBondContact OG-N 3.38Å; S282-E285 PolarHBondContact OG-OE2 2.88Å; S282-V286 WeakPolarHBondContact O-CG2 3.36Å; S282-V286 PolarHBondContact O-N 3.4Å
283	R	88.5	Confident	73.3	Confident	235 Å²	235	84.1 Å²	84.1	89%	0.887	51%	0.514	S	S	*	.	H	α-helix	trans	-56	-35.6	179.1	-65.6	-175.8	-178.6	178.2	0.4	113.1	A287	R283-A287 WeakPolarHBondContact O-CB 3.48Å; R283-A287 PolarHBondContact O-N 3.4Å
284	L	88.1	Confident	75.7	Confident	112 Å²	112	81.6 Å²	81.6	59%	0.586	49%	0.492	S	S	*	.	H	α-helix	trans	-72.3	-38.9	179	-170.2	67.3	0	0	0	111.5	L37 S282 A287 A288	L37-L284 HydrophobicContact CD1-CD2 3.65Å; L37-L284 HydrophobicContact CD1-CG 4.23Å; L37-L284 HydrophobicContact CD2-CB 4.39Å; L37-L284 HydrophobicContact CD2-CD2 3.93Å; L37-L284 HydrophobicContact CD2-CG 3.75Å; L37-L284 HydrophobicContact CG-CD2 4.39Å; S282-L284 PolarHBondContact O-N 3.29Å; S282-L284 VanDerWaalsContact O-N 3.16Å; L284-A287 PolarHBondContact O-N 2.95Å; L284-A288 WeakPolarHBondContact O-CB 3.36Å; L284-A288 PolarHBondContact O-N 3.18Å
285	E	89.1	Confident	78.2	Confident	19 Å²	19	77.1 Å²	77.1	9%	0.089	47%	0.473	C	S	.	.	H	α-helix	trans	-68.1	-41.7	174.6	-69.3	160.9	158.1	0	0	111.3	K36 L37 V40 L281 S282 A287 A288 L289	K36-E285 WeakPolarHBondContact CD-OE1 3.24Å; K36-E285 WeakPolarHBondContact CE-OE1 3.11Å; K36-E285 IonicContact NZ-OE1 3.38Å; K36-E285 PolarHBondContact NZ-OE1 2.93Å; L37-E285 HydrophobicContact CD2-CG 4.03Å; V40-E285 HydrophobicContact CG1-CB 4.23Å; V40-E285 WeakPolarHBondContact CG1-O 3.44Å; V40-E285 HydrophobicContact CG2-CB 4.15Å; V40-E285 HydrophobicContact CG2-CG 3.98Å; L281-E285 HydrophobicContact CB-CB 4Å; L281-E285 HydrophobicContact CD2-CB 4.21Å; S282-E285 VanDerWaalsContact CB-OE2 3.29Å; S282-E285 WeakPolarHBondContact CB-OE2 3.38Å; S282-E285 PolarHBondContact N-OE2 3.25Å; S282-E285 PolarHBondContact O-N 2.95Å; S282-E285 VanDerWaalsContact OG-CG 3.24Å; S282-E285 WeakPolarHBondContact OG-CG 3.41Å; S282-E285 PolarHBondContact OG-N 3.38Å; S282-E285 PolarHBondContact OG-OE2 2.88Å; E285-A287 VanDerWaalsContact C-N 3.32Å; E285-A287 PolarHBondContact O-N 2.65Å; E285-A288 PolarHBondContact O-N 3.41Å; E285-L289 WeakPolarHBondContact O-CB 3.31Å; E285-L289 PolarHBondContact O-N 3.31Å
286	V	90.3	Very high	80.1	Confident	65 Å²	65	72.2 Å²	72.2	39%	0.394	44%	0.438	S	S	.	.	H	α-helix	trans	-59.6	-45	172.8	175	0	0	0	0	110.5	L281 S282 A288 L289 V290	L281-V286 HydrophobicContact CB-CG2 3.65Å; S282-V286 WeakPolarHBondContact O-CG2 3.36Å; S282-V286 PolarHBondContact O-N 3.4Å; V286-A288 VanDerWaalsContact C-N 3.34Å; V286-A288 PolarHBondContact O-N 2.93Å; V286-L289 PolarHBondContact O-N 3.5Å; V286-V290 HydrophobicContact CG1-CG2 4.31Å; V286-V290 WeakPolarHBondContact O-CB 3.24Å; V286-V290 VanDerWaalsContact O-CG2 3.26Å; V286-V290 WeakPolarHBondContact O-CG2 3.47Å; V286-V290 PolarHBondContact O-N 3.22Å
287	A	92.7	Very high	82.3	Confident	55 Å²	55	69 Å²	69	46%	0.455	42%	0.416	S	S	.	.	H	α-helix	trans	-61.6	-41.8	176.3	0	0	0	0	0	112.1	R283 L284 E285 V290 L291	R283-A287 WeakPolarHBondContact O-CB 3.48Å; R283-A287 PolarHBondContact O-N 3.4Å; L284-A287 PolarHBondContact O-N 2.95Å; E285-A287 VanDerWaalsContact C-N 3.32Å; E285-A287 PolarHBondContact O-N 2.65Å; A287-V290 PolarHBondContact O-N 3.17Å; A287-L291 VanDerWaalsContact O-CB 3.29Å; A287-L291 WeakPolarHBondContact O-CB 3.31Å; A287-L291 PolarHBondContact O-N 3.28Å
288	A	91.8	Very high	84.5	Confident	15 Å²	15	70.6 Å²	70.6	12%	0.124	41%	0.411	C	S	.	.	H	α-helix	trans	-64.2	-42.2	175.3	0	0	0	0	0	112.1	L37 V40 L41 L284 E285 V286 L291 G292	L37-A288 HydrophobicContact CD2-CB 4.23Å; V40-A288 HydrophobicContact CB-CB 4.44Å; V40-A288 HydrophobicContact CG1-CB 4.4Å; L41-A288 WeakPolarHBondContact CD1-O 3.49Å; L284-A288 WeakPolarHBondContact O-CB 3.36Å; L284-A288 PolarHBondContact O-N 3.18Å; E285-A288 PolarHBondContact O-N 3.41Å; V286-A288 VanDerWaalsContact C-N 3.34Å; V286-A288 PolarHBondContact O-N 2.93Å; A288-L291 PolarHBondContact O-N 3.04Å; A288-G292 PolarHBondContact O-N 3.2Å
289	L	90.8	Very high	86.1	Confident	32 Å²	32	70.1 Å²	70.1	17%	0.168	39%	0.387	C	S	.	.	H	α-helix	trans	-61.3	-49.7	176.3	-175	71.5	0	0	0	111	V40 A43 L261 L281 E285 V286 L291 G292 C293	V40-L289 HydrophobicContact CG1-CB 3.74Å; V40-L289 HydrophobicContact CG1-CD1 4.25Å; A43-L289 HydrophobicContact CB-CD1 4.14Å; L261-L289 HydrophobicContact CD1-CD1 3.72Å; L261-L289 HydrophobicContact CD1-CD2 3.82Å; L261-L289 HydrophobicContact CD1-CG 4.46Å; L281-L289 HydrophobicContact CD1-CD2 3.93Å; E285-L289 WeakPolarHBondContact O-CB 3.31Å; E285-L289 PolarHBondContact O-N 3.31Å; V286-L289 PolarHBondContact O-N 3.5Å; L289-L291 VanDerWaalsContact C-N 3.35Å; L289-L291 PolarHBondContact O-N 3.43Å; L289-G292 WeakPolarHBondContact O-CA 3.19Å; L289-G292 PolarHBondContact O-N 3.28Å; L289-G292 VanDerWaalsContact O-N 3.15Å; L289-C293 PolarHBondContact O-N 3.43Å; L289-C293 PolarHBondContact O-SG 2.86Å; L289-C293 VanDerWaalsContact O-SG 3.39Å
290	V	92.6	Very high	87	Confident	75 Å²	75	63.3 Å²	63.3	46%	0.455	36%	0.359	S	S	.	.	H	α-helix	trans	-60.4	-46	178.6	170.8	0	0	0	0	110.4	V286 A287 G292 C293 L294	V286-V290 HydrophobicContact CG1-CG2 4.31Å; V286-V290 WeakPolarHBondContact O-CB 3.24Å; V286-V290 VanDerWaalsContact O-CG2 3.26Å; V286-V290 WeakPolarHBondContact O-CG2 3.47Å; V286-V290 PolarHBondContact O-N 3.22Å; A287-V290 PolarHBondContact O-N 3.17Å; V290-G292 VanDerWaalsContact C-N 3.28Å; V290-G292 PolarHBondContact O-N 3.42Å; V290-C293 PolarHBondContact O-N 2.67Å; V290-C293 VanDerWaalsContact O-N 3.14Å; V290-L294 HydrophobicContact CG1-CD1 3.86Å; V290-L294 HydrophobicContact CG1-CG 4.32Å; V290-L294 VanDerWaalsContact O-CG 3.3Å; V290-L294 WeakPolarHBondContact O-CG 3.33Å; V290-L294 PolarHBondContact O-N 3.07Å
291	L	93.5	Very high	87.4	Confident	97 Å²	97	65.4 Å²	65.4	51%	0.508	35%	0.353	S	S	.	.	H	α-helix	trans	-58.8	-43.1	175.9	-174.2	68.9	0	0	0	111.2	L41 A287 A288 L289 C293 L294 I295	L41-L291 HydrophobicContact CD1-CB 4.23Å; L41-L291 HydrophobicContact CD1-CD2 4.19Å; L41-L291 HydrophobicContact CD1-CG 4.27Å; A287-L291 VanDerWaalsContact O-CB 3.29Å; A287-L291 WeakPolarHBondContact O-CB 3.31Å; A287-L291 PolarHBondContact O-N 3.28Å; A288-L291 PolarHBondContact O-N 3.04Å; L289-L291 VanDerWaalsContact C-N 3.35Å; L289-L291 PolarHBondContact O-N 3.43Å; L291-C293 VanDerWaalsContact C-N 3.33Å; L291-C293 PolarHBondContact O-N 3.3Å; L291-L294 PolarHBondContact O-N 3.46Å; L291-I295 HydrophobicContact CG-CD1 4.11Å; L291-I295 HydrophobicContact CG-CG1 4.48Å; L291-I295 VanDerWaalsContact O-CG1 3.31Å; L291-I295 WeakPolarHBondContact O-CG1 3.14Å; L291-I295 PolarHBondContact O-N 3.37Å
292	G	91.4	Very high	86.6	Confident	0 Å²	0	65.8 Å²	65.8	0%	0	37%	0.368	C	S	.	.	H	α-helix	trans	-59.2	-42.5	175.2	0	0	0	0	0	112.3	G44 L45 A288 L289 V290 L294 P296	G44-G292 CarbonylContact C-O 3.42Å; G44-G292 CarbonylContact O-C 3.6Å; L45-G292 WeakPolarHBondContact CA-O 3.31Å; L45-G292 WeakPolarHBondContact CD2-O 3.48Å; L45-G292 PolarHBondContact N-O 3.23Å; A288-G292 PolarHBondContact O-N 3.2Å; L289-G292 WeakPolarHBondContact O-CA 3.19Å; L289-G292 PolarHBondContact O-N 3.28Å; L289-G292 VanDerWaalsContact O-N 3.15Å; V290-G292 VanDerWaalsContact C-N 3.28Å; V290-G292 PolarHBondContact O-N 3.42Å; G292-L294 VanDerWaalsContact C-N 3.33Å; G292-L294 PolarHBondContact O-N 3.04Å; G292-P296 WeakPolarHBondContact O-CD 3.17Å
293	C	91.5	Very high	85.2	Confident	38 Å²	38	68.1 Å²	68.1	26%	0.257	37%	0.373	S	S	.	.	H	α-helix	trans	-67	-33.3	176.5	-66.8	0	0	0	0	113	G44 L289 V290 L291	G44-C293 WeakPolarHBondContact O-CA 3.37Å; G44-C293 PolarHBondContact O-N 3.17Å; G44-C293 PolarHBondContact O-SG 3.03Å; L289-C293 PolarHBondContact O-N 3.43Å; L289-C293 PolarHBondContact O-SG 2.86Å; L289-C293 VanDerWaalsContact O-SG 3.39Å; V290-C293 PolarHBondContact O-N 2.67Å; V290-C293 VanDerWaalsContact O-N 3.14Å; L291-C293 VanDerWaalsContact C-N 3.33Å; L291-C293 PolarHBondContact O-N 3.3Å
294	L	92	Very high	83.2	Confident	84 Å²	84	64.7 Å²	64.7	44%	0.44	37%	0.366	S	S	.	.	H	α-helix	trans	-83.5	-27.6	-175.9	-67.5	177.6	0	0	0	113.7	V290 L291 G292 L297 V298	V290-L294 HydrophobicContact CG1-CD1 3.86Å; V290-L294 HydrophobicContact CG1-CG 4.32Å; V290-L294 VanDerWaalsContact O-CG 3.3Å; V290-L294 WeakPolarHBondContact O-CG 3.33Å; V290-L294 PolarHBondContact O-N 3.07Å; L291-L294 PolarHBondContact O-N 3.46Å; G292-L294 VanDerWaalsContact C-N 3.33Å; G292-L294 PolarHBondContact O-N 3.04Å; L294-L297 HydrophobicContact CD2-CD2 4.01Å; L294-L297 WeakPolarHBondContact O-CB 3.42Å; L294-L297 PolarHBondContact O-N 3.1Å; L294-V298 WeakPolarHBondContact O-CG2 3.09Å; L294-V298 PolarHBondContact O-N 3.02Å
295	I	90	Very high	80.7	Confident	63 Å²	63	71 Å²	71	32%	0.323	39%	0.392	S	S	.	.	H	α-helix	trans	-55.9	-51.7	179.3	-74.8	160.8	0	0	0	111.8	L41 L45 L291 L297 V298 L299	L41-I295 HydrophobicContact CD1-CD1 4.26Å; L45-I295 HydrophobicContact CD2-CB 3.83Å; L45-I295 HydrophobicContact CD2-CD1 4.15Å; L45-I295 HydrophobicContact CD2-CG2 3.79Å; L291-I295 HydrophobicContact CG-CD1 4.11Å; L291-I295 HydrophobicContact CG-CG1 4.48Å; L291-I295 VanDerWaalsContact O-CG1 3.31Å; L291-I295 WeakPolarHBondContact O-CG1 3.14Å; L291-I295 PolarHBondContact O-N 3.37Å; I295-L297 VanDerWaalsContact C-N 3.27Å; I295-L297 PolarHBondContact O-N 3.04Å; I295-V298 PolarHBondContact O-N 3.45Å; I295-L299 HydrophobicContact CG2-CD1 4.14Å; I295-L299 WeakPolarHBondContact O-CG 3.35Å; I295-L299 PolarHBondContact O-N 3.23Å; I295-L299 VanDerWaalsContact O-N 3.11Å
296	P	86.4	Confident	80.3	Confident	1 Å²	1	73.6 Å²	73.6	1%	0.006	41%	0.407	C	S	.	.	H	α-helix	trans	-63.7	-33.4	178.8	-22.4	34.8	0	0	0	112.7	L45 T49 V53 G292 L299 S300	L45-P296 HydrophobicContact CD2-CG 4.08Å; T49-P296 WeakPolarHBondContact OG1-CG 3.02Å; V53-P296 HydrophobicContact CG2-CB 3.87Å; G292-P296 WeakPolarHBondContact O-CD 3.17Å; P296-L299 PolarHBondContact O-N 3.24Å; P296-S300 WeakPolarHBondContact O-CB 3.49Å; P296-S300 PolarHBondContact O-N 3.38Å
297	L	86.2	Confident	79.8	Confident	73 Å²	73	74 Å²	74	38%	0.382	41%	0.408	S	S	.	.	H	α-helix	trans	-62.5	-44.8	176.1	-178.9	68.4	0	0	0	111.7	A52 L294 I295 L299 S300 I301	A52-L297 HydrophobicContact CB-CB 4.01Å; A52-L297 HydrophobicContact CB-CD1 3.85Å; L294-L297 HydrophobicContact CD2-CD2 4.01Å; L294-L297 WeakPolarHBondContact O-CB 3.42Å; L294-L297 PolarHBondContact O-N 3.1Å; I295-L297 VanDerWaalsContact C-N 3.27Å; I295-L297 PolarHBondContact O-N 3.04Å; L297-L299 VanDerWaalsContact C-N 3.32Å; L297-L299 PolarHBondContact O-N 2.87Å; L297-S300 PolarHBondContact O-N 3.37Å; L297-I301 HydrophobicContact CG-CD1 4.24Å; L297-I301 WeakPolarHBondContact O-CG1 3.21Å; L297-I301 PolarHBondContact O-N 3.25Å; L297-I301 VanDerWaalsContact O-N 3.09Å
298	V	86.6	Confident	79	Confident	103 Å²	103	75.1 Å²	75.1	62%	0.624	41%	0.405	S	S	*	.	H	α-helix	trans	-64.6	-39	176.3	175.2	0	0	0	0	111.1	L294 I295 S300 G302	L294-V298 WeakPolarHBondContact O-CG2 3.09Å; L294-V298 PolarHBondContact O-N 3.02Å; I295-V298 PolarHBondContact O-N 3.45Å; V298-S300 VanDerWaalsContact C-N 3.33Å; V298-G302 PolarHBondContact O-N 3.4Å
299	L	78.9	Confident	78.3	Confident	78 Å²	78	78.6 Å²	78.6	41%	0.408	42%	0.422	S	S	.	.	H	α-helix	trans	-64.8	-36.7	176.3	-66.2	174.4	0	0	0	112.2	I295 P296 L297	I295-L299 HydrophobicContact CG2-CD1 4.14Å; I295-L299 WeakPolarHBondContact O-CG 3.35Å; I295-L299 PolarHBondContact O-N 3.23Å; I295-L299 VanDerWaalsContact O-N 3.11Å; P296-L299 PolarHBondContact O-N 3.24Å; L297-L299 VanDerWaalsContact C-N 3.32Å; L297-L299 PolarHBondContact O-N 2.87Å
300	S	75.6	Confident	77.5	Confident	14 Å²	14	81.5 Å²	81.5	10%	0.098	44%	0.438	C	S	.	.	H	α-helix	trans	-68.2	-43.4	177.4	177.6	0	0	0	0	112.8	A52 P296 L297 V298 G302 H303	A52-S300 WeakPolarHBondContact O-CB 3.36Å; A52-S300 PolarHBondContact O-OG 3.35Å; P296-S300 WeakPolarHBondContact O-CB 3.49Å; P296-S300 PolarHBondContact O-N 3.38Å; L297-S300 PolarHBondContact O-N 3.37Å; V298-S300 VanDerWaalsContact C-N 3.33Å; S300-G302 PolarHBondContact O-N 3.02Å; S300-H303 PolarHBondContact O-N 3.05Å; S300-H303 VanDerWaalsContact O-N 3.16Å
301	I	74.8	Confident	76.5	Confident	112 Å²	112	81.9 Å²	81.9	57%	0.574	44%	0.437	S	S	*	.	H	α-helix	trans	-60.3	-33	179.9	-66.8	163.5	0	0	0	111.9	L297 H303	L297-I301 HydrophobicContact CG-CD1 4.24Å; L297-I301 WeakPolarHBondContact O-CG1 3.21Å; L297-I301 PolarHBondContact O-N 3.25Å; L297-I301 VanDerWaalsContact O-N 3.09Å; I301-H303 PolarHBondContact O-N 2.68Å
302	G	61.8	Low	75.3	Confident	54 Å²	54	80.9 Å²	80.9	56%	0.557	43%	0.431	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.6	-12.5	-179	0	0	0	0	0	115.4	V298 S300	V298-G302 PolarHBondContact O-N 3.4Å; S300-G302 PolarHBondContact O-N 3.02Å
303	H	56.1	Low	74.1	Confident	106 Å²	106	87.1 Å²	87.1	49%	0.491	47%	0.465	S	S	.	.	T	Hydrogen-bonded Turn	trans	-104.2	3.1	-173.8	-83.9	-149.3	0	0	0	114.2	V178 L182 S300 I301 H305	V178-H303 VanDerWaalsContact CG1-CE1 3.44Å; V178-H303 WeakPolarHBondContact CG1-CE1 3.26Å; L182-H303 VanDerWaalsContact CD1-CE1 3.41Å; L182-H303 WeakPolarHBondContact CD1-CE1 3.3Å; L182-H303 VanDerWaalsContact CD1-ND1 3.28Å; L182-H303 WeakPolarHBondContact CD1-ND1 3.3Å; S300-H303 PolarHBondContact O-N 3.05Å; S300-H303 VanDerWaalsContact O-N 3.16Å; I301-H303 PolarHBondContact O-N 2.68Å; H303-H305 PolarHBondContact O-N 3Å; H303-H305 VanDerWaalsContact O-N 3.11Å
304	H	46.7	Very low	72.6	Confident	162 Å²	162	91.2 Å²	91.2	75%	0.75	48%	0.482	S	S	*	.			trans	-80.9	26.2	-178.1	-110.4	-73.9	0	0	0	114.9
305	H	36.2	Very low	70.8	Confident	244 Å²	244	91.8 Å²	91.8	100%	1.13	49%	0.486	S	S	*	.			trans	-123	0	-177.3	-74.1	-55.7	0	0	0	113.3	H303	H303-H305 PolarHBondContact O-N 3Å; H303-H305 VanDerWaalsContact O-N 3.11Å

Retrieved 305 of 305 residues in 702.7 ms (Link to these results)

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