A0A093H9H0_STRCA Loading...

Dual specificity protein phosphatase 10

Protein phosphatase involved in the inactivation of MAP kinases. Has a specificity for the MAPK11/MAPK12/MAPK13/MAPK14 subfamily. It preferably dephosphorylates p38.

AlphaFold DB , UniProt , Accession A0A093H9H0, Species STRCA (Struthio camelus australis), Gene n/a, Length 481 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	33.2	Very low	38.7	Very low	237 Å²	237	147.7 Å²	147.7	100%	1.167	82%	0.824	S	S	*	*				0	138.1	0	-78.7	-175	132.7	0	0	107.9
2	P	27.8	Very low	39.4	Very low	113 Å²	113	142.9 Å²	142.9	73%	0.734	80%	0.801	S	S	*	*	P	Polyproline II helix	trans	-70.9	155	174.2	32.6	-31.7	0	0	0	110
3	P	32.8	Very low	39.6	Very low	131 Å²	131	139.5 Å²	139.5	85%	0.851	80%	0.802	S	S	*	*	P	Polyproline II helix	trans	-70.8	137.9	179.9	29.2	-31.9	0	0	0	110.7
4	S	30.4	Very low	40.2	Very low	114 Å²	114	135.5 Å²	135.5	80%	0.797	78%	0.776	S	S	*	*	P	Polyproline II helix	trans	-79.3	149.4	173.6	-61.2	0	0	0	0	110.7
5	P	42.2	Very low	40.4	Very low	126 Å²	126	135 Å²	135	82%	0.818	78%	0.784	S	S	*	*	P	Polyproline II helix	trans	-77.2	149.7	-167.2	32	-32.9	0	0	0	112.6
6	L	37.6	Very low	41.1	Very low	155 Å²	155	138.7 Å²	138.7	81%	0.812	78%	0.781	S	S	*	*	P	Polyproline II helix	trans	-54.7	131	179.8	-65.7	152.5	0	0	0	111.9	D8	L6-D8 PolarHBondContact O-N 3.02Å
7	D	38.8	Very low	41.6	Very low	125 Å²	125	138.8 Å²	138.8	67%	0.668	79%	0.788	S	S	*	*			trans	-73.7	94.3	164.3	-106.8	-47.8	0	0	0	108.1	R9	D7-R9 HydrophobicContact CB-CG 4.5Å; D7-R9 PolarHBondContact O-N 3.09Å; D7-R9 IonicContact OD1-CZ 3.83Å; D7-R9 IonicContact OD1-NE 3.66Å; D7-R9 PolarHBondContact OD1-NE 3.36Å; D7-R9 IonicContact OD1-NH2 3.07Å; D7-R9 PolarHBondContact OD1-NH2 2.59Å
8	D	43	Very low	42.5	Very low	153 Å²	153	133.6 Å²	133.6	82%	0.818	76%	0.76	S	S	*	*			trans	-74.6	57.5	173.9	-75.4	-27.4	0	0	0	111.7	L6	L6-D8 PolarHBondContact O-N 3.02Å
9	R	47.3	Very low	43.3	Very low	198 Å²	198	131.2 Å²	131.2	75%	0.747	74%	0.737	S	S	*	*			trans	-103.7	113.1	178.6	-59.4	-174.7	-166.4	-146.6	-0.4	110.7	D7	D7-R9 HydrophobicContact CB-CG 4.5Å; D7-R9 PolarHBondContact O-N 3.09Å; D7-R9 IonicContact OD1-CZ 3.83Å; D7-R9 IonicContact OD1-NE 3.66Å; D7-R9 PolarHBondContact OD1-NE 3.36Å; D7-R9 IonicContact OD1-NH2 3.07Å; D7-R9 PolarHBondContact OD1-NH2 2.59Å
10	V	44.9	Very low	43.9	Very low	136 Å²	136	130.4 Å²	130.4	82%	0.824	74%	0.738	S	S	*	*			trans	-89.3	118.5	172	-178.1	0	0	0	0	109.2	V12	V10-V12 HydrophobicContact CG1-CG2 4.12Å
11	V	48.2	Very low	44.5	Very low	137 Å²	137	131 Å²	131	83%	0.83	74%	0.735	S	S	*	*			trans	-103.1	119.4	176.8	-177.6	0	0	0	0	109
12	V	46.8	Very low	45.4	Very low	90 Å²	90	121.9 Å²	121.9	55%	0.545	69%	0.691	S	S	.	*			trans	-111.3	121.1	178	-176.5	0	0	0	0	109.3	V10 L53	V10-V12 HydrophobicContact CG1-CG2 4.12Å; V12-L53 HydrophobicContact CG1-CD1 4.06Å
13	A	41.9	Very low	46.7	Very low	99 Å²	99	119 Å²	119	82%	0.818	67%	0.669	S	S	*	*			trans	-77.1	125.1	175.2	0	0	0	0	0	110.4
14	L	47.5	Very low	47.7	Very low	83 Å²	83	118 Å²	118	44%	0.435	66%	0.656	S	S	.	*			trans	-89.4	139.1	172.8	-60.8	177.1	0	0	0	109.6	R16 V18 L23 L53	L14-R16 PolarHBondContact O-N 3.22Å; L14-V18 HydrophobicContact CD1-CB 4.48Å; L14-V18 HydrophobicContact CD1-CG2 4.37Å; L14-L23 HydrophobicContact CD1-CD1 3.78Å; L14-L53 HydrophobicContact CD2-CD1 4.46Å
15	S	44.3	Very low	48.7	Very low	128 Å²	128	118.6 Å²	118.6	90%	0.895	65%	0.65	S	S	*	*	S	Bend	trans	-69.1	-12	-179.6	46.9	0	0	0	0	113.8
16	R	51	Low	49.1	Very low	194 Å²	194	115.1 Å²	115.1	73%	0.732	63%	0.628	S	S	*	*	S	Bend	trans	-147.1	152.5	176.6	-62.1	-175	-178.4	171.3	0.8	111.5	L14 V18	L14-R16 PolarHBondContact O-N 3.22Å; R16-V18 PolarHBondContact O-N 3.1Å
17	P	50.1	Low	49.7	Very low	140 Å²	140	114.7 Å²	114.7	91%	0.909	63%	0.626	S	S	*	*			trans	-64.9	126	173.9	-15.5	29	0	0	0	110.7
18	V	57.3	Low	50.1	Low	46 Å²	46	111.5 Å²	111.5	28%	0.279	61%	0.609	S	S	.	*			trans	-124.1	141.5	176.4	-174.5	0	0	0	0	108.4	L14 R16 D22 L23	L14-V18 HydrophobicContact CD1-CB 4.48Å; L14-V18 HydrophobicContact CD1-CG2 4.37Å; R16-V18 PolarHBondContact O-N 3.1Å; V18-D22 HydrophobicContact CG1-CB 4.07Å; V18-L23 HydrophobicContact CB-CD1 4.06Å; V18-L23 HydrophobicContact CG1-CD1 3.91Å
19	R	57.1	Low	50.5	Low	87 Å²	87	108.1 Å²	108.1	33%	0.328	60%	0.597	S	S	.	*			trans	-69.5	140.2	176.1	-68.9	-178.2	-78.2	-134.4	-1.9	109.7	Q21 D22 T59	R19-Q21 HydrophobicContact CB-CG 4.21Å; R19-Q21 PolarHBondContact O-N 3.43Å; R19-Q21 VanDerWaalsContact O-N 3.13Å; R19-D22 WeakPolarHBondContact CB-OD2 3.26Å; R19-D22 IonicContact CZ-OD2 3.1Å; R19-D22 IonicContact NE-OD2 2.67Å; R19-D22 PolarHBondContact NE-OD2 2.94Å; R19-D22 IonicContact NH2-OD2 3.25Å; R19-D22 PolarHBondContact O-N 3.07Å; R19-T59 PolarHBondContact NH2-OG1 3.42Å; R19-T59 VanDerWaalsContact NH2-OG1 3.09Å
20	P	55.4	Low	50.7	Low	115 Å²	115	102.6 Å²	102.6	75%	0.747	59%	0.589	S	S	*	*	G	3₁₀ helix	trans	-54.9	-35.1	-178.4	-27.5	35	0	0	0	114	D22 L23	P20-D22 VanDerWaalsContact C-N 3.25Å; P20-D22 PolarHBondContact O-N 3.35Å; P20-L23 PolarHBondContact O-N 3.06Å
21	Q	56.5	Low	50.8	Low	144 Å²	144	104.5 Å²	104.5	67%	0.673	58%	0.582	S	S	*	*	G	3₁₀ helix	trans	-69.9	-16.5	178	63.6	-113	36.7	0	0	115.2	R19	R19-Q21 HydrophobicContact CB-CG 4.21Å; R19-Q21 PolarHBondContact O-N 3.43Å; R19-Q21 VanDerWaalsContact O-N 3.13Å
22	D	51.8	Low	50.8	Low	45 Å²	45	105 Å²	105	24%	0.241	58%	0.58	C	S	.	*	G	3₁₀ helix	trans	-96	1.7	-178.4	-58.7	-27.5	0	0	0	111	V18 R19 P20	V18-D22 HydrophobicContact CG1-CB 4.07Å; R19-D22 WeakPolarHBondContact CB-OD2 3.26Å; R19-D22 IonicContact CZ-OD2 3.1Å; R19-D22 IonicContact NE-OD2 2.67Å; R19-D22 PolarHBondContact NE-OD2 2.94Å; R19-D22 IonicContact NH2-OD2 3.25Å; R19-D22 PolarHBondContact O-N 3.07Å; P20-D22 VanDerWaalsContact C-N 3.25Å; P20-D22 PolarHBondContact O-N 3.35Å
23	L	55.6	Low	50.8	Low	53 Å²	53	110 Å²	110	28%	0.277	60%	0.597	S	S	.	*	E	Extended strand (participates in β ladder)	trans	-94.9	110.8	179.7	-133.6	98.2	0	0	0	110.6	L14 V18 P20 L25 L53	L14-L23 HydrophobicContact CD1-CD1 3.78Å; V18-L23 HydrophobicContact CB-CD1 4.06Å; V18-L23 HydrophobicContact CG1-CD1 3.91Å; P20-L23 PolarHBondContact O-N 3.06Å; L23-L25 HydrophobicContact CD2-CD2 4.16Å; L23-L25 HydrophobicContact CD2-CG 4.38Å; L23-L53 HydrophobicContact CD2-CD2 4.15Å
24	N	53.7	Low	51	Low	110 Å²	110	110.3 Å²	110.3	59%	0.588	59%	0.593	S	S	*	*	E	Extended strand (participates in β ladder)	trans	-102.2	113.9	170.5	-82.2	-40.4	0	0	0	110
25	L	52.3	Low	50.8	Low	127 Å²	127	113.1 Å²	113.1	67%	0.665	61%	0.613	S	S	*	*	E	Extended strand (participates in β ladder)	trans	-91.5	119.5	174.8	-65.1	168.9	0	0	0	108.9	L23 L53	L23-L25 HydrophobicContact CD2-CD2 4.16Å; L23-L25 HydrophobicContact CD2-CG 4.38Å; L25-L53 HydrophobicContact CD2-CD2 3.36Å; L25-L53 HydrophobicContact CD2-CG 4.37Å
26	C	50.6	Low	50.7	Low	53 Å²	53	112.3 Å²	112.3	36%	0.358	61%	0.608	S	S	.	*	E	Extended strand (participates in β ladder)	trans	-119.9	134.8	171	52.6	0	0	0	0	110	D28 S52	C26-D28 PolarHBondContact O-N 3.37Å; C26-S52 PolarHBondContact SG-O 3.13Å; C26-S52 VanDerWaalsContact SG-O 3.36Å
27	L	48.9	Very low	50.2	Low	145 Å²	145	108.7 Å²	108.7	76%	0.759	61%	0.612	S	S	*	*	E	Extended strand (participates in β ladder)	trans	-74.7	124.1	170.3	-68.2	169.1	0	0	0	108.1	V51	L27-V51 HydrophobicContact CD2-CG2 4.21Å
28	D	47.6	Very low	49.6	Very low	58 Å²	58	106.4 Å²	106.4	31%	0.31	61%	0.605	S	S	.	*			trans	-96.7	97.5	178.8	-166.1	-11.8	0	0	0	109	C26 S30	C26-D28 PolarHBondContact O-N 3.37Å; D28-S30 VanDerWaalsContact C-N 3.32Å; D28-S30 VanDerWaalsContact OD1-CB 3.26Å; D28-S30 WeakPolarHBondContact OD1-CB 3.49Å; D28-S30 PolarHBondContact OD1-N 3.49Å; D28-S30 PolarHBondContact OD1-OG 3.2Å
29	S	52.2	Low	48.8	Very low	82 Å²	82	109.8 Å²	109.8	57%	0.573	63%	0.631	S	S	*	*			trans	-90.7	8.6	-179.8	53.3	0	0	0	0	113.3	Y31 L32	S29-Y31 PolarHBondContact O-N 3.15Å; S29-L32 PolarHBondContact O-N 3.45Å; S29-L32 VanDerWaalsContact O-N 3.1Å
30	S	50.4	Low	48.2	Very low	82 Å²	82	115.1 Å²	115.1	57%	0.573	66%	0.66	S	S	*	*	T	Hydrogen-bonded Turn	trans	-61.1	-17.4	-178.5	58.1	0	0	0	0	114.2	D28	D28-S30 VanDerWaalsContact C-N 3.32Å; D28-S30 VanDerWaalsContact OD1-CB 3.26Å; D28-S30 WeakPolarHBondContact OD1-CB 3.49Å; D28-S30 PolarHBondContact OD1-N 3.49Å; D28-S30 PolarHBondContact OD1-OG 3.2Å
31	Y	46.8	Very low	47.4	Very low	177 Å²	177	114.6 Å²	114.6	69%	0.694	66%	0.659	S	S	*	*	T	Hydrogen-bonded Turn	trans	-86	-6.4	177.7	-79.6	-92.2	0	0	0	115	S29	S29-Y31 PolarHBondContact O-N 3.15Å
32	L	50	Low	46.8	Very low	148 Å²	148	117.8 Å²	117.8	78%	0.775	67%	0.673	S	S	*	*	S	Bend	trans	-88.2	-7.9	-173.6	-82.1	165.8	0	0	0	115.2	S29 S34	S29-L32 PolarHBondContact O-N 3.45Å; S29-L32 VanDerWaalsContact O-N 3.1Å; L32-S34 PolarHBondContact O-N 3.38Å
33	E	44.8	Very low	46.1	Very low	194 Å²	194	119.9 Å²	119.9	91%	0.907	69%	0.691	S	S	*	*	T	Hydrogen-bonded Turn	trans	-85	2.6	-173.2	-83.1	-173	165.9	0	0	116
34	S	47	Very low	45.2	Very low	106 Å²	106	123.1 Å²	123.1	74%	0.741	72%	0.718	S	S	*	*	T	Hydrogen-bonded Turn	trans	-110.1	20.7	-172.8	74	0	0	0	0	117.2	L32	L32-S34 PolarHBondContact O-N 3.38Å
35	V	43.6	Very low	44.4	Very low	141 Å²	141	125.4 Å²	125.4	86%	0.855	73%	0.73	S	S	*	*			trans	-130	78.8	173.3	-166.2	0	0	0	0	111
36	S	41	Very low	43.6	Very low	112 Å²	112	127.3 Å²	127.3	78%	0.783	74%	0.74	S	S	*	*			trans	-112.4	138.3	161.6	-173.7	0	0	0	0	109.9
37	S	41.1	Very low	43.2	Very low	117 Å²	117	128.2 Å²	128.2	82%	0.818	76%	0.758	S	S	*	*			trans	79.7	96.3	175.6	76.6	0	0	0	0	117.9
38	A	38.2	Very low	42.6	Very low	93 Å²	93	127.5 Å²	127.5	77%	0.769	76%	0.76	S	S	*	*				165.5	124.6	107.1	0	0	0	0	0	112.7
39	S	39.5	Very low	42.3	Very low	117 Å²	117	128.7 Å²	128.7	82%	0.818	78%	0.778	S	S	*	*			trans	55.3	126.8	152.5	61.4	0	0	0	0	121.9
40	E	46.2	Very low	41.7	Very low	199 Å²	199	128.1 Å²	128.1	93%	0.93	77%	0.771	S	S	*	*			trans	-45.7	121.3	172.8	-64.5	167.9	151.5	0	0	115.2
41	S	37.3	Very low	41.4	Very low	104 Å²	104	128 Å²	128	73%	0.727	77%	0.766	S	S	*	*			trans	-157.7	136	139.6	54.8	0	0	0	0	108.6	S43	S41-S43 PolarHBondContact O-N 3.33Å
42	H	45.3	Very low	41.2	Very low	210 Å²	210	121.3 Å²	121.3	97%	0.972	75%	0.745	S	S	*	*			trans	-60.7	101.9	-178.5	-82.1	-84.5	0	0	0	110.9
43	S	36.7	Very low	40.9	Very low	89 Å²	89	117.6 Å²	117.6	62%	0.622	73%	0.726	S	S	*	*			trans	-126	128.3	157.2	70.1	0	0	0	0	108	S41 L45	S41-S43 PolarHBondContact O-N 3.33Å; S43-L45 VanDerWaalsContact C-N 3.34Å; S43-L45 PolarHBondContact O-N 3.29Å
44	S	35.2	Very low	40.8	Very low	121 Å²	121	115.3 Å²	115.3	85%	0.846	71%	0.713	S	S	*	*			trans	-68.3	93.4	172.4	50	0	0	0	0	108.7	L46	S44-L46 PolarHBondContact O-N 3Å; S44-L46 VanDerWaalsContact O-N 3.14Å
45	L	37.2	Very low	40.7	Very low	159 Å²	159	114 Å²	114	83%	0.832	70%	0.701	S	S	*	*			trans	-63.2	107.9	170.7	-90.7	149.9	0	0	0	109.3	S43 G47	S43-L45 VanDerWaalsContact C-N 3.34Å; S43-L45 PolarHBondContact O-N 3.29Å; L45-G47 VanDerWaalsContact C-N 3.32Å; L45-G47 PolarHBondContact O-N 3.14Å
46	L	36.2	Very low	40.6	Very low	166 Å²	166	110.2 Å²	110.2	87%	0.869	68%	0.684	S	S	*	*			trans	-66.1	93.1	161	-84.2	158.3	0	0	0	107.9	S44 T48	S44-L46 PolarHBondContact O-N 3Å; S44-L46 VanDerWaalsContact O-N 3.14Å; L46-T48 PolarHBondContact O-N 2.95Å
47	G	41.5	Very low	40.5	Very low	72 Å²	72	111.8 Å²	111.8	74%	0.742	68%	0.684	S	S	*	*			trans	-64.7	118.5	173.8	0	0	0	0	0	110.5	L45 A49	L45-G47 VanDerWaalsContact C-N 3.32Å; L45-G47 PolarHBondContact O-N 3.14Å; G47-A49 PolarHBondContact O-N 2.93Å
48	T	37.6	Very low	40.4	Very low	130 Å²	130	112.9 Å²	112.9	80%	0.798	68%	0.68	S	S	*	*			trans	-79.1	106.8	171.7	-57.3	0	0	0	0	108.3	L46 V50	L46-T48 PolarHBondContact O-N 2.95Å; T48-V50 HydrophobicContact CG2-CG2 4.47Å
49	A	40.1	Very low	40.3	Very low	84 Å²	84	113 Å²	113	69%	0.694	67%	0.671	S	S	*	*			trans	-82.9	115.3	171.9	0	0	0	0	0	109.5	G47	G47-A49 PolarHBondContact O-N 2.93Å
50	V	40	Very low	40.2	Very low	69 Å²	69	116.2 Å²	116.2	42%	0.418	67%	0.667	S	S	.	*	P	Polyproline II helix	trans	-89.9	116.7	174	-178.6	0	0	0	0	108.4	T48	T48-V50 HydrophobicContact CG2-CG2 4.47Å
51	V	44.7	Very low	39.6	Very low	80 Å²	80	113.3 Å²	113.3	49%	0.485	65%	0.654	S	S	.	*	E	Extended strand (participates in β ladder)	trans	-99.4	117.6	176	-176.4	0	0	0	0	108.6	L27	L27-V51 HydrophobicContact CD2-CG2 4.21Å
52	S	42.5	Very low	39.4	Very low	36 Å²	36	112.5 Å²	112.5	25%	0.252	65%	0.647	S	S	.	*	E	Extended strand (participates in β ladder)	trans	-95.6	121.3	178	-170.4	0	0	0	0	110.2	C26	C26-S52 PolarHBondContact SG-O 3.13Å; C26-S52 VanDerWaalsContact SG-O 3.36Å
53	L	44	Very low	38.9	Very low	70 Å²	70	107.9 Å²	107.9	37%	0.366	64%	0.638	S	S	.	*	E	Extended strand (participates in β ladder)	trans	-90	108.4	177.4	-78.2	153.6	0	0	0	109.5	V12 L14 L23 L25	V12-L53 HydrophobicContact CG1-CD1 4.06Å; L14-L53 HydrophobicContact CD2-CD1 4.46Å; L23-L53 HydrophobicContact CD2-CD2 4.15Å; L25-L53 HydrophobicContact CD2-CD2 3.36Å; L25-L53 HydrophobicContact CD2-CG 4.37Å
54	K	43	Very low	38.7	Very low	146 Å²	146	109.1 Å²	109.1	64%	0.635	65%	0.647	S	S	*	*	E	Extended strand (participates in β ladder)	trans	-104.6	116.5	170.1	-77.1	-178.6	179.1	172.6	0	109.7
55	T	44.5	Very low	38.9	Very low	79 Å²	79	111.3 Å²	111.3	49%	0.485	65%	0.649	S	S	.	*	E	Extended strand (participates in β ladder)	trans	-92.3	130.1	170.9	52.6	0	0	0	0	109
56	A	40.1	Very low	39	Very low	61 Å²	61	107.3 Å²	107.3	50%	0.504	65%	0.646	S	S	.	*			trans	-118	138.4	173.2	0	0	0	0	0	109.2
57	N	40.5	Very low	38.9	Very low	146 Å²	146	104.7 Å²	104.7	78%	0.781	64%	0.642	S	S	*	*			trans	57.8	74.4	177.2	-65.4	-24.3	0	0	0	115.3	T59	N57-T59 PolarHBondContact O-N 3.21Å
58	L	39	Very low	38.4	Very low	140 Å²	140	106.2 Å²	106.2	73%	0.733	65%	0.647	S	S	*	*			trans	-63.8	101.6	167.8	-69.8	164.9	0	0	0	110.3
59	T	35.8	Very low	37.9	Very low	94 Å²	94	111 Å²	111	58%	0.577	65%	0.651	S	S	*	*			trans	-92.6	109.3	161.4	8	0	0	0	0	109.5	R19 N57	R19-T59 PolarHBondContact NH2-OG1 3.42Å; R19-T59 VanDerWaalsContact NH2-OG1 3.09Å; N57-T59 PolarHBondContact O-N 3.21Å
60	Y	37	Very low	37.5	Very low	186 Å²	186	112 Å²	112	73%	0.729	65%	0.653	S	S	*	*			trans	-60.4	134.8	175.8	176.8	-109	0	0	0	111.5	P62	Y60-P62 HydrophobicContact CD1-CB 4.27Å; Y60-P62 HydrophobicContact CD1-CG 3.87Å; Y60-P62 VanDerWaalsContact CE1-CA 3.43Å; Y60-P62 HydrophobicContact CE1-CB 3.68Å; Y60-P62 HydrophobicContact CE1-CG 3.8Å; Y60-P62 WeakPolarHBondContact O-CD 3.48Å
61	M	33.8	Very low	36.9	Very low	137 Å²	137	117.3 Å²	117.3	68%	0.675	68%	0.678	S	S	*	*			trans	-94	112.5	161.8	-79.8	-162.8	75.4	0	0	108.6	S63	M61-S63 PolarHBondContact O-N 2.88Å
62	P	32.6	Very low	36.3	Very low	88 Å²	88	118.4 Å²	118.4	57%	0.571	69%	0.689	S	S	*	*			trans	-69.6	128.7	164.9	-3.9	19.8	0	0	0	108.3	Y60 S64	Y60-P62 HydrophobicContact CD1-CB 4.27Å; Y60-P62 HydrophobicContact CD1-CG 3.87Å; Y60-P62 VanDerWaalsContact CE1-CA 3.43Å; Y60-P62 HydrophobicContact CE1-CB 3.68Å; Y60-P62 HydrophobicContact CE1-CG 3.8Å; Y60-P62 WeakPolarHBondContact O-CD 3.48Å; P62-S64 PolarHBondContact O-N 2.89Å; P62-S64 VanDerWaalsContact O-N 3.15Å
63	S	34.9	Very low	35.6	Very low	113 Å²	113	122.3 Å²	122.3	79%	0.79	72%	0.715	S	S	*	*			trans	-68.6	106.2	168.1	54.9	0	0	0	0	109.2	M61	M61-S63 PolarHBondContact O-N 2.88Å
64	S	32.5	Very low	35.2	Very low	115 Å²	115	122.5 Å²	122.5	80%	0.804	73%	0.734	S	S	*	*			trans	-76	129	164.8	53.7	0	0	0	0	109.6	P62	P62-S64 PolarHBondContact O-N 2.89Å; P62-S64 VanDerWaalsContact O-N 3.15Å
65	N	38.9	Very low	34.4	Very low	167 Å²	167	120.7 Å²	120.7	89%	0.893	74%	0.739	S	S	*	*	S	Bend	trans	-38.5	132.5	176.3	-78	-23.1	0	0	0	114.5
66	G	40.4	Very low	34	Very low	74 Å²	74	123.3 Å²	123.3	76%	0.763	76%	0.76	S	S	*	*	S	Bend	trans	83.3	115.7	151.6	0	0	0	0	0	116.6
67	S	33.7	Very low	33.5	Very low	112 Å²	112	125.2 Å²	125.2	78%	0.783	77%	0.77	S	S	*	*			trans	81	89.9	165.5	-148.9	0	0	0	0	116.7
68	A	30.5	Very low	33.3	Very low	104 Å²	104	123.5 Å²	123.5	86%	0.86	78%	0.776	S	S	*	*			trans	-88.7	95.4	151.8	0	0	0	0	0	108.3	S70	A68-S70 PolarHBondContact O-N 3.17Å
69	R	28.2	Very low	33.1	Very low	230 Å²	230	122.2 Å²	122.2	87%	0.868	78%	0.779	S	S	*	*			trans	-62.6	111.6	156.3	-78.3	-178.2	174.8	175.8	-1.1	106.7	L71	R69-L71 PolarHBondContact O-N 3.39Å
70	S	31.7	Very low	32.9	Very low	106 Å²	106	123.5 Å²	123.5	74%	0.741	79%	0.79	S	S	*	*			trans	-70.3	127.4	168	78.2	0	0	0	0	108.3	A68 S72	A68-S70 PolarHBondContact O-N 3.17Å; S70-S72 PolarHBondContact O-N 3.1Å; S70-S72 VanDerWaalsContact O-N 3.1Å
71	L	27.4	Very low	32.4	Very low	179 Å²	179	120.8 Å²	120.8	94%	0.937	80%	0.797	S	S	*	*			trans	-71.2	98.5	165.2	-74.8	163.1	0	0	0	106.6	R69 C73	R69-L71 PolarHBondContact O-N 3.39Å; L71-C73 PolarHBondContact O-N 3.11Å
72	S	30.7	Very low	32	Very low	103 Å²	103	120.9 Å²	120.9	72%	0.72	81%	0.805	S	S	*	*			trans	-75.7	111.9	174	56.1	0	0	0	0	110.2	S70	S70-S72 PolarHBondContact O-N 3.1Å; S70-S72 VanDerWaalsContact O-N 3.1Å
73	C	27.7	Very low	31.7	Very low	118 Å²	118	123 Å²	123	80%	0.797	82%	0.816	S	S	*	*			trans	-82.6	103.9	150.3	171.1	0	0	0	0	106.8	L71 C75	L71-C73 PolarHBondContact O-N 3.11Å; C73-C75 PolarHBondContact O-N 2.94Å
74	G	35.2	Very low	31.2	Very low	74 Å²	74	121.2 Å²	121.2	76%	0.763	81%	0.808	S	S	*	*			trans	-88.2	90.9	179.9	0	0	0	0	0	111.5
75	C	28	Very low	30.9	Very low	109 Å²	109	122 Å²	122	74%	0.736	81%	0.808	S	S	*	*			trans	-140	98.1	165	-63.9	0	0	0	0	109.4	C73	C73-C75 PolarHBondContact O-N 2.94Å
76	S	34.7	Very low	30.3	Very low	133 Å²	133	124.6 Å²	124.6	93%	0.93	81%	0.807	S	S	*	*			trans	-102.1	86.5	162.2	-61.7	0	0	0	0	108.1
77	S	30.2	Very low	29.8	Very low	102 Å²	102	128.5 Å²	128.5	71%	0.713	81%	0.811	S	S	*	*			trans	-146.4	112.7	163.5	-60.9	0	0	0	0	106.2	S79	S77-S79 PolarHBondContact O-N 2.87Å
78	A	35.8	Very low	29.4	Very low	109 Å²	109	132.7 Å²	132.7	90%	0.901	82%	0.815	S	S	*	*	S	Bend	trans	-62.7	123	166.3	0	0	0	0	0	107.1
79	S	35.8	Very low	29.3	Very low	114 Å²	114	135.5 Å²	135.5	80%	0.797	82%	0.815	S	S	*	*	S	Bend	trans	100.1	79.8	-177.3	-153.6	0	0	0	0	114.2	S77	S77-S79 PolarHBondContact O-N 2.87Å
80	C	31.1	Very low	29.5	Very low	121 Å²	121	130.4 Å²	130.4	82%	0.818	81%	0.81	S	S	*	*			trans	173.3	82.3	148.6	-88.8	0	0	0	0	108
81	C	25.8	Very low	29.3	Very low	128 Å²	128	134.7 Å²	134.7	87%	0.865	82%	0.818	S	S	*	*			trans	-164.5	70.4	157.9	-93.5	0	0	0	0	107.6
82	T	26.7	Very low	29.3	Very low	140 Å²	140	130.3 Å²	130.3	86%	0.859	81%	0.807	S	S	*	*			trans	-79.3	110.8	158.6	-17.8	0	0	0	0	106
83	V	25.2	Very low	29.1	Very low	133 Å²	133	133.6 Å²	133.6	81%	0.806	81%	0.812	S	S	*	*			trans	-112.5	93.7	159.3	-178.8	0	0	0	0	105.9
84	A	25.4	Very low	29	Very low	74 Å²	74	133.6 Å²	133.6	61%	0.612	81%	0.808	S	S	*	*			trans	-68.2	129.8	161.5	0	0	0	0	0	107.8
85	T	26.8	Very low	28.6	Very low	133 Å²	133	138.5 Å²	138.5	82%	0.816	81%	0.811	S	S	*	*			trans	-64.6	128.5	164.2	45.4	0	0	0	0	108.8
86	Y	25.9	Very low	28.4	Very low	220 Å²	220	137.4 Å²	137.4	86%	0.863	81%	0.81	S	S	*	*			trans	-129.4	136	158.8	-98.7	-82.4	0	0	0	109.8
87	D	28.7	Very low	28	Very low	157 Å²	157	136 Å²	136	84%	0.84	80%	0.8	S	S	*	*			trans	-61.5	151.8	-169.6	-76.4	-58	0	0	0	114.6
88	K	26.8	Very low	27.7	Very low	200 Å²	200	137.2 Å²	137.2	87%	0.87	80%	0.803	S	S	*	*			trans	-94.8	95.7	172.9	-161.8	-176.5	-170.1	-177.3	0	107.7
89	D	28.3	Very low	27.2	Very low	162 Å²	162	137 Å²	137	87%	0.866	80%	0.795	S	S	*	*			trans	-83.2	138.7	165.5	-99.2	-31.7	0	0	0	111.3
90	T	31.2	Very low	26.7	Very low	123 Å²	123	136.9 Å²	136.9	76%	0.755	79%	0.794	S	S	*	*			trans	-90.3	132.9	-172.9	-50	0	0	0	0	109
91	Q	28.1	Very low	26.5	Very low	197 Å²	197	135.5 Å²	135.5	92%	0.921	79%	0.792	S	S	*	*			trans	-160	130.8	146.8	-111.1	164.9	48	0	0	112
92	A	27.7	Very low	26.5	Very low	86 Å²	86	137.7 Å²	137.7	71%	0.711	79%	0.789	S	S	*	*			trans	-78.3	154.7	177.9	0	0	0	0	0	112
93	Q	26.5	Very low	26.5	Very low	173 Å²	173	137.9 Å²	137.9	81%	0.808	79%	0.79	S	S	*	*				156.9	137.4	121.1	-89	178.8	-8.2	0	0	112.8
94	T	25.2	Very low	26.5	Very low	118 Å²	118	134.9 Å²	134.9	72%	0.724	79%	0.786	S	S	*	*			trans	62.7	140	149.1	44.5	0	0	0	0	117.8
95	Q	26.1	Very low	26.5	Very low	176 Å²	176	136.1 Å²	136.1	82%	0.822	80%	0.796	S	S	*	*			cis	-168.1	147.6	25.9	-127.3	166.7	19.5	0	0	109.1
96	A	24.7	Very low	26.4	Very low	87 Å²	87	134.3 Å²	134.3	72%	0.719	79%	0.789	S	S	*	*			trans	16	138.8	149.2	0	0	0	0	0	123.8
97	S	25.2	Very low	26.4	Very low	102 Å²	102	130.3 Å²	130.3	71%	0.713	79%	0.788	S	S	*	*				115.4	117	120.4	70.4	0	0	0	0	119.5
98	T	24.2	Very low	26.2	Very low	128 Å²	128	127.3 Å²	127.3	79%	0.785	79%	0.785	S	S	*	*			trans	59.2	135	131.3	57.7	0	0	0	0	118.6
99	S	25.4	Very low	26	Very low	104 Å²	104	123.5 Å²	123.5	73%	0.727	78%	0.782	S	S	*	*			cis	-176.9	153.8	28.2	40.4	0	0	0	0	110
100	S	25.6	Very low	26.4	Very low	112 Å²	112	121.5 Å²	121.5	78%	0.783	78%	0.778	S	S	*	*			trans	17.7	151.4	139.5	72.1	0	0	0	0	120.3
101	A	26.2	Very low	26.2	Very low	93 Å²	93	119.6 Å²	119.6	77%	0.769	78%	0.775	S	S	*	*			cis	-168	164.5	27.4	0	0	0	0	0	111.7
102	H	26.1	Very low	26.1	Very low	174 Å²	174	117.6 Å²	117.6	81%	0.806	77%	0.77	S	S	*	*			trans	-41.1	162.9	166.2	-75.9	-82.2	0	0	0	120.7
103	T	26.3	Very low	25.9	Very low	144 Å²	144	122.6 Å²	122.6	88%	0.883	78%	0.779	S	S	*	*			trans	131.8	132.4	130.7	55.9	0	0	0	0	110.6
104	G	25.8	Very low	25.8	Very low	69 Å²	69	122.9 Å²	122.9	71%	0.711	78%	0.782	S	S	*	*			cis	174.2	150.2	-0.6	0	0	0	0	0	108.9
105	A	25.8	Very low	25.7	Very low	100 Å²	100	124.1 Å²	124.1	83%	0.826	79%	0.79	S	S	*	*			trans	48.6	140.6	143.5	0	0	0	0	0	120
106	S	25.6	Very low	25.6	Very low	96 Å²	96	122.9 Å²	122.9	67%	0.671	79%	0.788	S	S	*	*			cis	176.5	147.3	19.3	34.9	0	0	0	0	110.8
107	T	24.7	Very low	25.6	Very low	135 Å²	135	124.4 Å²	124.4	83%	0.828	79%	0.794	S	S	*	*			trans	49.2	144.8	138.1	56.4	0	0	0	0	121.1
108	A	24.5	Very low	25.6	Very low	94 Å²	94	125.8 Å²	125.8	78%	0.777	79%	0.793	S	S	*	*			cis	-169.1	161.4	4	0	0	0	0	0	109.2
109	C	22.1	Very low	25.6	Very low	121 Å²	121	127.7 Å²	127.7	82%	0.818	79%	0.793	S	S	*	*			trans	-59.8	-176	167.9	-58	0	0	0	0	113.1
110	P	38.5	Very low	25.7	Very low	120 Å²	120	130.7 Å²	130.7	78%	0.779	80%	0.801	S	S	*	*			cis	-151.9	174.9	17.7	42.2	-19.3	0	0	0	120.4
111	A	25.6	Very low	25.7	Very low	83 Å²	83	129.9 Å²	129.9	69%	0.686	80%	0.802	S	S	*	*			trans	66.1	122.1	135.5	0	0	0	0	0	124.8
112	N	26	Very low	25.7	Very low	154 Å²	154	129.2 Å²	129.2	82%	0.824	80%	0.804	S	S	*	*				48.8	127.8	129.9	-68	-7.9	0	0	0	122.3
113	Q	24.3	Very low	25.7	Very low	191 Å²	191	126.5 Å²	126.5	89%	0.893	80%	0.804	S	S	*	*				-174.1	144.6	108.5	-104.3	177.7	7.5	0	0	113.8
114	M	23.7	Very low	25.7	Very low	180 Å²	180	127.6 Å²	127.6	89%	0.887	80%	0.804	S	S	*	*			trans	-82.3	146.9	171.3	-64.5	163.4	67.6	0	0	111
115	V	24.4	Very low	25.8	Very low	144 Å²	144	129.5 Å²	129.5	87%	0.873	81%	0.806	S	S	*	*			trans	-148.1	131.8	149.7	-172.2	0	0	0	0	110.9
116	N	23.7	Very low	26.5	Very low	149 Å²	149	130.3 Å²	130.3	80%	0.797	80%	0.803	S	S	*	*			trans	-71.5	156.8	170.7	-120.1	4.6	0	0	0	112
117	S	23.3	Very low	26.6	Very low	120 Å²	120	134.5 Å²	134.5	84%	0.839	82%	0.817	S	S	*	*			trans	172.9	125.6	130.1	-75.9	0	0	0	0	114.4
118	N	25	Very low	26.7	Very low	131 Å²	131	132 Å²	132	70%	0.701	82%	0.819	S	S	*	*			trans	1.4	145.9	147.5	-92.3	17.9	0	0	0	124.9
119	E	25.6	Very low	26.8	Very low	167 Å²	167	131.2 Å²	131.2	78%	0.78	82%	0.819	S	S	*	*			trans	65.8	120.9	133.9	-65.6	171.7	145.5	0	0	120.5
120	N	26.3	Very low	27.2	Very low	167 Å²	167	132.8 Å²	132.8	89%	0.893	83%	0.825	S	S	*	*				-173.3	153.3	103.2	-143	-8.1	0	0	0	113.4
121	A	26.6	Very low	26.7	Very low	96 Å²	96	130.5 Å²	130.5	79%	0.793	82%	0.823	S	S	*	*			trans	-76.8	155.5	178.1	0	0	0	0	0	113.5
122	G	25.8	Very low	27	Very low	79 Å²	79	132.2 Å²	132.2	81%	0.814	83%	0.83	S	S	*	*			trans	-176.9	95.8	170.8	0	0	0	0	0	113.3
123	S	26.6	Very low	27.5	Very low	117 Å²	117	130 Å²	130	82%	0.818	82%	0.824	S	S	*	*			trans	-60.6	138.6	163.6	174.2	0	0	0	0	110.7
124	L	26.4	Very low	27.9	Very low	167 Å²	167	128.6 Å²	128.6	87%	0.874	83%	0.828	S	S	*	*			trans	178.5	129	145.3	-93.9	157.7	0	0	0	110.4
125	S	26.7	Very low	28.2	Very low	109 Å²	109	124.6 Å²	124.6	76%	0.762	82%	0.818	S	S	*	*			trans	-116.5	173.3	166.6	-46.5	0	0	0	0	108.1
126	P	41.7	Very low	28.5	Very low	116 Å²	116	121.3 Å²	121.3	75%	0.753	81%	0.813	S	S	*	*			cis	-129.2	163.6	-41.9	33.6	-17.6	0	0	0	111.5
127	L	27.5	Very low	28.9	Very low	184 Å²	184	119.5 Å²	119.5	96%	0.963	81%	0.807	S	S	*	*			trans	-155.6	134.8	154.5	-105.2	142.8	0	0	0	110
128	G	26.8	Very low	29.6	Very low	84 Å²	84	119.7 Å²	119.7	87%	0.866	80%	0.804	S	S	*	*			trans	-81.5	165.6	-161.2	0	0	0	0	0	116.5
129	G	26.8	Very low	30.8	Very low	77 Å²	77	122.4 Å²	122.4	79%	0.794	81%	0.809	S	S	*	*			trans	177.1	80.9	175.9	0	0	0	0	0	112.6
130	V	30.6	Very low	32.2	Very low	154 Å²	154	121.5 Å²	121.5	93%	0.933	81%	0.805	S	S	*	*			trans	-2.5	131.3	159.8	-169.8	0	0	0	0	119
131	G	28.2	Very low	33.8	Very low	71 Å²	71	115.1 Å²	115.1	73%	0.732	77%	0.771	S	S	*	*			trans	177.8	38.2	167.9	0	0	0	0	0	119.8
132	S	31	Very low	35.4	Very low	119 Å²	119	114.2 Å²	114.2	83%	0.832	76%	0.763	S	S	*	*			trans	58.2	153.8	155.2	-73.8	0	0	0	0	123.3
133	P	36.5	Very low	37.5	Very low	108 Å²	108	115.6 Å²	115.6	70%	0.701	76%	0.76	S	S	*	*			trans	-117.8	151.7	-138.9	38.7	-26.4	0	0	0	115.2
134	V	32.2	Very low	40.2	Very low	161 Å²	161	111.3 Å²	111.3	98%	0.976	73%	0.728	S	S	*	*			trans	-128.1	79.2	149.1	-177.9	0	0	0	0	107
135	S	31	Very low	43.2	Very low	97 Å²	97	108.5 Å²	108.5	68%	0.678	71%	0.709	S	S	*	*			trans	-108	101.7	170.2	179.7	0	0	0	0	107.9	T137	S135-T137 PolarHBondContact O-N 3.45Å
136	G	29.3	Very low	46.4	Very low	74 Å²	74	106.5 Å²	106.5	76%	0.763	69%	0.688	S	S	*	*			trans	-65.2	98.6	165.3	0	0	0	0	0	108.7	T138	G136-T138 PolarHBondContact O-N 3.4Å
137	T	32.1	Very low	48.9	Very low	111 Å²	111	101.3 Å²	101.3	68%	0.681	66%	0.655	S	S	*	*			trans	-59.1	119.5	171.2	48.3	0	0	0	0	109.3	S135 K139	S135-T137 PolarHBondContact O-N 3.45Å; T137-K139 PolarHBondContact O-N 3.48Å
138	T	39.9	Very low	52.1	Low	125 Å²	125	98 Å²	98	77%	0.767	63%	0.63	S	S	*	*			trans	-56.3	102.9	161.7	35.6	0	0	0	0	108.1	G136 Q140	G136-T138 PolarHBondContact O-N 3.4Å; T138-Q140 PolarHBondContact O-N 2.81Å
139	K	48.9	Very low	55.3	Low	187 Å²	187	94.6 Å²	94.6	81%	0.813	59%	0.593	S	S	*	*			trans	-64.8	103.5	170.8	-86.8	-175.9	175.9	179	0	107.6	T137 L141	T137-K139 PolarHBondContact O-N 3.48Å; K139-L141 PolarHBondContact O-N 3.07Å
140	Q	55.4	Low	58.5	Low	149 Å²	149	94.9 Å²	94.9	70%	0.696	58%	0.576	S	S	*	*	P	Polyproline II helix	trans	-59.8	130.2	170.2	-161.9	168.7	12.5	0	0	108	T138 A142 S241	T138-Q140 PolarHBondContact O-N 2.81Å; Q140-A142 PolarHBondContact O-N 2.86Å; Q140-S241 PolarHBondContact NE2-O 2.64Å
141	L	59.5	Low	61.4	Low	33 Å²	33	90.8 Å²	90.8	17%	0.173	55%	0.549	C	S	.	.	P	Polyproline II helix	trans	-60.1	124.1	-176.5	-144.5	78.2	0	0	0	108.3	K139 I144 L253 K257	K139-L141 PolarHBondContact O-N 3.07Å; L141-I144 HydrophobicContact CB-CD1 4.12Å; L141-I144 HydrophobicContact CB-CG1 4.4Å; L141-I144 HydrophobicContact CD2-CD1 3.79Å; L141-I144 HydrophobicContact CD2-CG1 3.9Å; L141-L253 HydrophobicContact CD2-CB 3.88Å; L141-L253 HydrophobicContact CD2-CD1 4.32Å; L141-K257 HydrophobicContact CD1-CD 4.39Å; L141-K257 HydrophobicContact CD2-CD 3.99Å; L141-K257 HydrophobicContact CG-CD 4.03Å
142	A	61.4	Low	64.5	Low	76 Å²	76	87.4 Å²	87.4	63%	0.628	51%	0.514	S	S	*	.	S	Bend	trans	-50.7	155.3	176.8	0	0	0	0	0	111.7	Q140 I144 K257	Q140-A142 PolarHBondContact O-N 2.86Å; A142-I144 PolarHBondContact O-N 2.97Å; A142-K257 PolarHBondContact O-NZ 3.17Å
143	S	69.6	Low	67.3	Low	108 Å²	108	82 Å²	82	76%	0.755	48%	0.476	S	S	*	.			trans	-29.1	106.6	-170.6	62.4	0	0	0	0	113.7
144	I	82.6	Confident	69.9	Low	28 Å²	28	82.1 Å²	82.1	14%	0.144	47%	0.466	C	S	.	.			trans	-82.8	124.7	178.5	-62.8	164.8	0	0	0	108	L141 A142 P240 L253 V265	L141-I144 HydrophobicContact CB-CD1 4.12Å; L141-I144 HydrophobicContact CB-CG1 4.4Å; L141-I144 HydrophobicContact CD2-CD1 3.79Å; L141-I144 HydrophobicContact CD2-CG1 3.9Å; A142-I144 PolarHBondContact O-N 2.97Å; I144-P240 HydrophobicContact CB-CB 4.06Å; I144-P240 VanDerWaalsContact CD1-C 3.46Å; I144-P240 HydrophobicContact CD1-CB 3.75Å; I144-P240 WeakPolarHBondContact CD1-O 3.48Å; I144-P240 HydrophobicContact CG2-CB 3.64Å; I144-P240 HydrophobicContact CG2-CG 4.36Å; I144-L253 HydrophobicContact CD1-CD1 4.43Å; I144-V265 HydrophobicContact CG2-CB 4.07Å; I144-V265 HydrophobicContact CG2-CG2 3.46Å; I144-V265 VanDerWaalsContact CG2-CG2 3.46Å
145	K	90.1	Very high	72.5	Confident	108 Å²	108	78 Å²	78	47%	0.47	44%	0.435	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-77.3	141.1	175.6	-62.9	175.4	-176.9	156.8	0	109.4	E262 L264 V265	K145-E262 IonicContact NZ-OE2 3.24Å; K145-E262 PolarHBondContact NZ-OE2 3.23Å; K145-L264 HydrophobicContact CB-CD2 3.48Å; K145-L264 VanDerWaalsContact CB-CD2 3.48Å; K145-L264 WeakPolarHBondContact O-CA 3.37Å; K145-V265 PolarHBondContact O-N 3.4Å
146	I	93.5	Very high	75.1	Confident	66 Å²	66	74.8 Å²	74.8	34%	0.338	41%	0.41	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-116.6	141.6	-174	-59.2	179.6	0	0	0	109	P240 V265 K267	I146-P240 HydrophobicContact CD1-CG 4.13Å; I146-P240 HydrophobicContact CG1-CG 4.12Å; I146-V265 CarbonylContact C-O 3.46Å; I146-V265 WeakPolarHBondContact CA-O 3.37Å; I146-K267 HydrophobicContact CG2-CB 3.6Å; I146-K267 HydrophobicContact CG2-CD 4.32Å; I146-K267 HydrophobicContact CG2-CG 4.16Å
147	I	94.4	Very high	77.5	Confident	8 Å²	8	74.4 Å²	74.4	4%	0.041	39%	0.392	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-115.4	139.5	166.3	-170.7	169.7	0	0	0	109.9	D151 L152 K155 I231 L264 V265 L266 K267	I147-D151 HydrophobicContact CD1-CB 4.35Å; I147-D151 HydrophobicContact CG1-CB 3.96Å; I147-L152 HydrophobicContact CD1-CB 3.94Å; I147-L152 HydrophobicContact CG1-CB 4.34Å; I147-K155 HydrophobicContact CD1-CD 3.82Å; I147-I231 HydrophobicContact CD1-CD1 3.92Å; I147-I231 HydrophobicContact CG2-CG2 3.86Å; I147-L264 HydrophobicContact CB-CB 4.31Å; I147-L264 HydrophobicContact CG2-CB 4.14Å; I147-V265 PolarHBondContact N-O 3.12Å; I147-L266 HydrophobicContact CG2-CB 4.35Å; I147-L266 HydrophobicContact CG2-CD1 4.2Å; I147-L266 WeakPolarHBondContact O-CA 3.5Å; I147-K267 PolarHBondContact O-N 3.45Å
148	Y	94.8	Very high	79.1	Confident	114 Å²	114	76.5 Å²	76.5	45%	0.447	39%	0.392	S	S	.	.			trans	-89.2	151	176.5	-68.8	-91.1	0	0	0	110.9	N150 D151 L152 K267	Y148-N150 VanDerWaalsContact C-N 3.29Å; Y148-N150 PolarHBondContact O-N 2.87Å; Y148-D151 PolarHBondContact O-N 2.62Å; Y148-L152 PolarHBondContact O-N 3.06Å; Y148-K267 HydrophobicContact CD1-CB 4.42Å; Y148-K267 HydrophobicContact CD1-CD 3.86Å; Y148-K267 HydrophobicContact CE1-CD 3.33Å
149	P	93.5	Very high	79.8	Confident	13 Å²	13	72.9 Å²	72.9	8%	0.084	37%	0.371	C	S	.	.	H	α-helix	trans	-48.5	-45.8	-180	-33.8	37.6	0	0	0	115.4	D151 L152 A153 L266 F273	P149-D151 VanDerWaalsContact C-N 3.28Å; P149-D151 PolarHBondContact O-N 2.92Å; P149-L152 PolarHBondContact O-N 2.71Å; P149-A153 WeakPolarHBondContact O-CB 3.45Å; P149-A153 PolarHBondContact O-N 3.29Å; P149-L266 HydrophobicContact CG-CD1 4.23Å; P149-F273 HydrophobicContact CB-CB 4.47Å; P149-F273 HydrophobicContact CB-CD2 3.92Å
150	N	93.3	Very high	79.9	Confident	83 Å²	83	68.9 Å²	68.9	44%	0.444	37%	0.367	S	S	.	.	H	α-helix	trans	-63.8	-33.5	179.8	-66.5	-22.8	0	0	0	112.8	Y148 K154 H277	Y148-N150 VanDerWaalsContact C-N 3.29Å; Y148-N150 PolarHBondContact O-N 2.87Å; N150-K154 WeakPolarHBondContact O-CB 3.41Å; N150-K154 WeakPolarHBondContact O-CD 3.28Å; N150-K154 VanDerWaalsContact O-CG 3.22Å; N150-K154 WeakPolarHBondContact O-CG 3.36Å; N150-K154 PolarHBondContact O-N 3.2Å; N150-K154 VanDerWaalsContact O-N 3.11Å; N150-H277 PolarHBondContact OD1-NE2 3.44Å
151	D	93.1	Very high	79.5	Confident	68 Å²	68	71.1 Å²	71.1	36%	0.364	37%	0.374	S	S	.	.	H	α-helix	trans	-77.6	-36.5	179.9	-61.8	-38.8	0	0	0	111.3	I147 Y148 P149 K154 K155	I147-D151 HydrophobicContact CD1-CB 4.35Å; I147-D151 HydrophobicContact CG1-CB 3.96Å; Y148-D151 PolarHBondContact O-N 2.62Å; P149-D151 VanDerWaalsContact C-N 3.28Å; P149-D151 PolarHBondContact O-N 2.92Å; D151-K154 PolarHBondContact O-N 3.27Å; D151-K154 IonicContact OD1-NZ 3.99Å; D151-K155 WeakPolarHBondContact O-CG 3.39Å; D151-K155 PolarHBondContact O-N 2.93Å
152	L	92.8	Very high	78.7	Confident	0 Å²	0	72.7 Å²	72.7	0%	0	39%	0.388	C	S	.	.	H	α-helix	trans	-61.6	-50	171	175.6	53.7	0	0	0	110.9	I147 Y148 P149 K154 K155 M156 I171 I185 I231 L266 F273	I147-L152 HydrophobicContact CD1-CB 3.94Å; I147-L152 HydrophobicContact CG1-CB 4.34Å; Y148-L152 PolarHBondContact O-N 3.06Å; P149-L152 PolarHBondContact O-N 2.71Å; L152-K154 VanDerWaalsContact C-N 3.31Å; L152-K154 PolarHBondContact O-N 3.45Å; L152-K155 WeakPolarHBondContact O-CA 2.95Å; L152-K155 WeakPolarHBondContact O-CB 3.46Å; L152-K155 PolarHBondContact O-N 3.1Å; L152-M156 HydrophobicContact CD1-CG 4.08Å; L152-M156 HydrophobicContact CD1-SD 4.14Å; L152-M156 HydrophobicContact CG-CG 4.5Å; L152-M156 HydrophobicContact CG-SD 4.06Å; L152-M156 WeakPolarHBondContact O-CG 3.5Å; L152-M156 PolarHBondContact O-N 3.29Å; L152-I171 HydrophobicContact CD1-CD1 4.18Å; L152-I185 HydrophobicContact CD2-CD1 3.87Å; L152-I231 HydrophobicContact CD1-CD1 3.49Å; L152-I231 VanDerWaalsContact CD1-CD1 3.49Å; L152-I231 HydrophobicContact CD1-CG2 4.49Å; L152-I231 HydrophobicContact CD2-CG2 4.35Å; L152-L266 HydrophobicContact CB-CD1 4.32Å; L152-L266 HydrophobicContact CD2-CD1 3.81Å; L152-L266 HydrophobicContact CD2-CD2 3.8Å; L152-L266 HydrophobicContact CD2-CG 4.35Å; L152-F273 HydrophobicContact CB-CE2 4Å; L152-F273 HydrophobicContact CD2-CD2 3.99Å; L152-F273 HydrophobicContact CD2-CE2 3.75Å; L152-F273 HydrophobicContact CD2-CZ 4.48Å; L152-F273 HydrophobicContact CG-CD2 4.41Å; L152-F273 HydrophobicContact CG-CE2 3.75Å; L152-F273 HydrophobicContact CG-CZ 4.43Å
153	A	89.9	Confident	77.9	Confident	5 Å²	5	78.9 Å²	78.9	4%	0.041	40%	0.403	C	S	.	.	H	α-helix	trans	-59	-40.6	178.6	0	0	0	0	0	112.6	P149 K155 M156 T157 F273 H277 L280	P149-A153 WeakPolarHBondContact O-CB 3.45Å; P149-A153 PolarHBondContact O-N 3.29Å; A153-K155 PolarHBondContact O-N 2.88Å; A153-M156 PolarHBondContact O-N 3.17Å; A153-T157 WeakPolarHBondContact O-CG2 3.33Å; A153-T157 PolarHBondContact O-N 2.97Å; A153-T157 PolarHBondContact O-OG1 2.91Å; A153-F273 HydrophobicContact CB-CE2 4.24Å; A153-F273 HydrophobicContact CB-CZ 4.41Å; A153-H277 HydrophobicContact CB-CB 4.5Å; A153-H277 VanDerWaalsContact CB-CE1 3.4Å; A153-H277 WeakPolarHBondContact CB-CE1 3.38Å; A153-H277 WeakPolarHBondContact CB-ND1 3.35Å; A153-L280 HydrophobicContact CB-CD1 3.66Å
154	K	89.6	Confident	76.7	Confident	110 Å²	110	80.3 Å²	80.3	48%	0.478	40%	0.398	S	S	.	.	H	α-helix	trans	-62.1	-40.7	172.7	-75.4	169.4	-171.3	169.9	0	112.2	N150 D151 L152 T157 K158	N150-K154 WeakPolarHBondContact O-CB 3.41Å; N150-K154 WeakPolarHBondContact O-CD 3.28Å; N150-K154 VanDerWaalsContact O-CG 3.22Å; N150-K154 WeakPolarHBondContact O-CG 3.36Å; N150-K154 PolarHBondContact O-N 3.2Å; N150-K154 VanDerWaalsContact O-N 3.11Å; D151-K154 PolarHBondContact O-N 3.27Å; D151-K154 IonicContact OD1-NZ 3.99Å; L152-K154 VanDerWaalsContact C-N 3.31Å; L152-K154 PolarHBondContact O-N 3.45Å; K154-T157 PolarHBondContact O-OG1 3.47Å; K154-K158 VanDerWaalsContact O-CB 3.32Å; K154-K158 WeakPolarHBondContact O-CB 3.15Å; K154-K158 WeakPolarHBondContact O-CG 3.17Å; K154-K158 PolarHBondContact O-N 3.41Å
155	K	87.4	Confident	74.9	Confident	74 Å²	74	88.2 Å²	88.2	32%	0.322	44%	0.435	S	S	.	.	H	α-helix	trans	-66.7	-39	177.2	-76.4	173.2	179.9	-102.2	0	111.7	I147 D151 L152 A153 E229	I147-K155 HydrophobicContact CD1-CD 3.82Å; D151-K155 WeakPolarHBondContact O-CG 3.39Å; D151-K155 PolarHBondContact O-N 2.93Å; L152-K155 WeakPolarHBondContact O-CA 2.95Å; L152-K155 WeakPolarHBondContact O-CB 3.46Å; L152-K155 PolarHBondContact O-N 3.1Å; A153-K155 PolarHBondContact O-N 2.88Å; K155-E229 WeakPolarHBondContact CE-OE2 3.2Å; K155-E229 IonicContact NZ-OE1 2.95Å; K155-E229 PolarHBondContact NZ-OE1 3.3Å; K155-E229 IonicContact NZ-OE2 2.69Å; K155-E229 PolarHBondContact NZ-OE2 3.05Å
156	M	85.4	Confident	73.1	Confident	31 Å²	31	88 Å²	88	15%	0.153	44%	0.438	C	S	.	.	H	α-helix	trans	-64.7	-43.9	176.2	-67.6	175	72.8	0	0	112	L152 A153 I171 I185 Q186 F273 L280	L152-M156 HydrophobicContact CD1-CG 4.08Å; L152-M156 HydrophobicContact CD1-SD 4.14Å; L152-M156 HydrophobicContact CG-CG 4.5Å; L152-M156 HydrophobicContact CG-SD 4.06Å; L152-M156 WeakPolarHBondContact O-CG 3.5Å; L152-M156 PolarHBondContact O-N 3.29Å; A153-M156 PolarHBondContact O-N 3.17Å; M156-I171 HydrophobicContact CE-CD1 4.08Å; M156-I171 HydrophobicContact CG-CD1 4.15Å; M156-I171 HydrophobicContact SD-CD1 3.91Å; M156-I185 HydrophobicContact CE-CG2 3.56Å; M156-I185 HydrophobicContact SD-CG2 3.72Å; M156-Q186 HydrophobicContact CE-CB 4.1Å; M156-F273 HydrophobicContact SD-CZ 3.97Å; M156-L280 HydrophobicContact CE-CB 4.32Å
157	T	79.9	Confident	71.5	Confident	65 Å²	65	92 Å²	92	40%	0.399	46%	0.456	S	S	.	.	H	α-helix	trans	-80.5	-28.6	-175.4	51.3	0	0	0	0	114.5	A153 K154 C159 S160 L280	A153-T157 WeakPolarHBondContact O-CG2 3.33Å; A153-T157 PolarHBondContact O-N 2.97Å; A153-T157 PolarHBondContact O-OG1 2.91Å; K154-T157 PolarHBondContact O-OG1 3.47Å; T157-C159 VanDerWaalsContact C-N 3.28Å; T157-C159 PolarHBondContact O-N 3.34Å; T157-S160 PolarHBondContact O-N 2.87Å; T157-L280 HydrophobicContact CG2-CD1 4.32Å; T157-L280 HydrophobicContact CG2-CD2 4.36Å
158	K	66.4	Low	70.4	Confident	156 Å²	156	92.5 Å²	92.5	68%	0.678	46%	0.463	S	S	*	.	H	α-helix	trans	-65	-29.6	176.6	-81.2	176	-179.8	-175.4	0	113.1	K154 S160	K154-K158 VanDerWaalsContact O-CB 3.32Å; K154-K158 WeakPolarHBondContact O-CB 3.15Å; K154-K158 WeakPolarHBondContact O-CG 3.17Å; K154-K158 PolarHBondContact O-N 3.41Å; K158-S160 VanDerWaalsContact C-N 3.26Å; K158-S160 PolarHBondContact O-N 3.13Å
159	C	54.8	Low	70	Confident	48 Å²	48	88.2 Å²	88.2	32%	0.324	45%	0.449	S	S	.	.	T	Hydrogen-bonded Turn	trans	-73.2	-14	178.5	-67.8	0	0	0	0	113.9	T157	T157-C159 VanDerWaalsContact C-N 3.28Å; T157-C159 PolarHBondContact O-N 3.34Å
160	S	50.5	Low	69.7	Low	103 Å²	103	88.3 Å²	88.3	72%	0.72	45%	0.449	S	S	*	.	T	Hydrogen-bonded Turn	trans	-83.9	-15.8	-177.9	-51.3	0	0	0	0	114.2	T157 K158	T157-S160 PolarHBondContact O-N 2.87Å; K158-S160 VanDerWaalsContact C-N 3.26Å; K158-S160 PolarHBondContact O-N 3.13Å
161	K	46.8	Very low	69.6	Low	196 Å²	196	84.8 Å²	84.8	85%	0.852	43%	0.43	S	S	*	.	S	Bend	trans	-98.7	-9.7	-171.9	-68.2	-171.6	178.4	-176.1	0	115.5
162	S	42.8	Very low	69.6	Low	66 Å²	66	81.5 Å²	81.5	46%	0.462	41%	0.413	S	S	.	.	S	Bend	trans	-105.5	130.4	175.2	53.7	0	0	0	0	110.1	Q164	S162-Q164 PolarHBondContact O-N 3.33Å
163	H	44.8	Very low	69.5	Low	206 Å²	206	81.5 Å²	81.5	95%	0.954	41%	0.413	S	S	*	.	S	Bend	trans	-62.6	25.5	174.4	-85.5	10.3	0	0	0	115.4
164	Q	43.4	Very low	69.6	Low	139 Å²	139	81.3 Å²	81.3	65%	0.65	41%	0.411	S	S	*	.			trans	-102.8	100	163.8	-75.3	-176.8	-17.7	0	0	108.2	S162 N166	S162-Q164 PolarHBondContact O-N 3.33Å; Q164-N166 PolarHBondContact O-N 2.99Å
165	Q	46.2	Very low	69.6	Low	194 Å²	194	76.5 Å²	76.5	91%	0.907	39%	0.39	S	S	*	.			trans	-55	125.1	170.5	-83	174.2	-14.6	0	0	109.7
166	N	51.5	Low	69.2	Low	103 Å²	103	75.3 Å²	75.3	55%	0.551	39%	0.39	S	S	*	.			trans	91.8	42.8	146.6	-136.8	-2.4	0	0	0	120.2	Q164 K228	Q164-N166 PolarHBondContact O-N 2.99Å; N166-K228 VanDerWaalsContact O-CE 3.28Å; N166-K228 WeakPolarHBondContact O-CE 3.03Å; N166-K228 PolarHBondContact O-NZ 3.29Å
167	Q	59.8	Low	68.7	Low	149 Å²	149	75.2 Å²	75.2	70%	0.696	39%	0.389	S	S	*	.			trans	-109.5	23.8	169.8	-65.3	-140.4	37.2	0	0	115.3
168	G	72	Confident	68.2	Low	19 Å²	19	74.4 Å²	74.4	20%	0.196	38%	0.381	C	S	.	.	P	Polyproline II helix	trans	-68.9	158.9	173.4	0	0	0	0	0	113.2	K228	G168-K228 WeakPolarHBondContact O-CD 3.42Å
169	P	85.3	Confident	68.8	Low	25 Å²	25	70.1 Å²	70.1	16%	0.162	36%	0.363	C	S	.	.	P	Polyproline II helix	trans	-62.7	152.4	173.8	29.3	-35	0	0	0	110.9	E229 I231	P169-E229 CarbonylContact C-O 3.58Å; P169-E229 VanDerWaalsContact CA-O 3.31Å; P169-E229 WeakPolarHBondContact CA-O 3.29Å; P169-E229 HydrophobicContact CB-CB 4.35Å; P169-E229 WeakPolarHBondContact CB-O 3.5Å; P169-I231 HydrophobicContact CB-CD1 3.66Å; P169-I231 HydrophobicContact CB-CG1 4.14Å; P169-I231 HydrophobicContact CG-CD1 3.83Å
170	V	87.8	Confident	70	Confident	14 Å²	14	69.4 Å²	69.4	9%	0.085	35%	0.354	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-82.6	117.9	171	177.7	0	0	0	0	107.9	I172 I213 I225 K228 E229 I230 I231	V170-I172 HydrophobicContact CG1-CG1 4.28Å; V170-I213 HydrophobicContact CG1-CD1 4.41Å; V170-I225 HydrophobicContact CG2-CG2 4.46Å; V170-K228 HydrophobicContact CG2-CB 3.91Å; V170-K228 HydrophobicContact CG2-CD 3.87Å; V170-E229 PolarHBondContact N-O 3.01Å; V170-I230 HydrophobicContact CB-CG1 4.49Å; V170-I230 WeakPolarHBondContact O-CA 3.36Å; V170-I231 PolarHBondContact O-N 3.38Å
171	I	91.6	Very high	71.1	Confident	9 Å²	9	65.6 Å²	65.6	5%	0.046	33%	0.326	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-100.9	128.8	-178.9	-50.5	177	0	0	0	108.4	L152 M156 I185 A188 V189 I231 Y233	L152-I171 HydrophobicContact CD1-CD1 4.18Å; M156-I171 HydrophobicContact CE-CD1 4.08Å; M156-I171 HydrophobicContact CG-CD1 4.15Å; M156-I171 HydrophobicContact SD-CD1 3.91Å; I171-I185 HydrophobicContact CD1-CG2 3.95Å; I171-A188 HydrophobicContact CB-CB 4.19Å; I171-A188 HydrophobicContact CG2-CB 3.89Å; I171-A188 CarbonylContact O-C 3.57Å; I171-A188 WeakPolarHBondContact O-CA 3.24Å; I171-V189 PolarHBondContact O-N 2.84Å; I171-I231 CarbonylContact C-O 3.5Å; I171-I231 WeakPolarHBondContact CA-O 3.43Å; I171-Y233 HydrophobicContact CG2-CD1 3.86Å; I171-Y233 HydrophobicContact CG2-CE1 3.6Å
172	I	92.1	Very high	72.6	Confident	0 Å²	0	60.7 Å²	60.7	0%	0	31%	0.305	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-119	123.1	-177.5	-59.9	176.4	0	0	0	109.4	V170 V189 I191 V209 I213 I230 I231 V232 Y233 V252 L256	V170-I172 HydrophobicContact CG1-CG1 4.28Å; I172-V189 WeakPolarHBondContact CA-O 3.29Å; I172-I191 HydrophobicContact CG2-CB 4.27Å; I172-I191 HydrophobicContact CG2-CG1 3.68Å; I172-V209 HydrophobicContact CD1-CG1 3.86Å; I172-I213 HydrophobicContact CD1-CD1 3.77Å; I172-I213 HydrophobicContact CG1-CD1 4.27Å; I172-I230 HydrophobicContact CD1-CG2 3.54Å; I172-I230 HydrophobicContact CG1-CG2 4.25Å; I172-I231 PolarHBondContact N-O 2.66Å; I172-V232 HydrophobicContact CB-CG1 4.42Å; I172-V232 HydrophobicContact CB-CG2 4.26Å; I172-V232 HydrophobicContact CD1-CG2 4.36Å; I172-V232 HydrophobicContact CG2-CG1 4.35Å; I172-V232 WeakPolarHBondContact O-CA 3.22Å; I172-Y233 WeakPolarHBondContact O-CD1 3.24Å; I172-Y233 PolarHBondContact O-N 3.36Å; I172-V252 HydrophobicContact CG2-CG1 4.14Å; I172-L256 HydrophobicContact CD1-CD1 4.07Å
173	D	91.5	Very high	74.5	Confident	0 Å²	0	57.9 Å²	57.9	0%	0	29%	0.285	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-97.2	120.5	170.8	-169.4	-33.9	0	0	0	109.5	R175 Y180 A188 V189 I191 Y233	D173-R175 WeakPolarHBondContact OD1-CB 3.49Å; D173-R175 WeakPolarHBondContact OD1-CG 3.23Å; D173-R175 PolarHBondContact OD1-N 3.36Å; D173-R175 IonicContact OD1-NE 3Å; D173-R175 PolarHBondContact OD1-NE 3.45Å; D173-R175 IonicContact OD2-CZ 2.62Å; D173-R175 IonicContact OD2-NE 3.75Å; D173-R175 PolarHBondContact OD2-NE 2.85Å; D173-R175 VanDerWaalsContact OD2-NE 3.1Å; D173-R175 IonicContact OD2-NH2 3.54Å; D173-R175 PolarHBondContact OD2-NH2 3.03Å; D173-Y180 HydrophobicContact CB-CD2 3.72Å; D173-Y180 HydrophobicContact CB-CE2 4.17Å; D173-Y180 WeakPolarHBondContact OD2-CD2 3.47Å; D173-A188 HydrophobicContact CB-CB 4.41Å; D173-V189 PolarHBondContact N-O 3.18Å; D173-I191 PolarHBondContact O-N 2.86Å; D173-Y233 HydrophobicContact CB-CE1 3.81Å; D173-Y233 HydrophobicContact CB-CE2 4.23Å; D173-Y233 WeakPolarHBondContact OD2-CE2 3.3Å; D173-Y233 PolarHBondContact OD2-OH 3.02Å
174	C	91.2	Very high	76.7	Confident	1 Å²	1	49.5 Å²	49.5	1%	0.007	25%	0.246	C	C	.	.			trans	-105.4	6.5	179.2	70.3	0	0	0	0	114.2	V232 Y233 P248 L249 V252	C174-V232 HydrophobicContact CB-CG1 4.5Å; C174-Y233 PolarHBondContact N-O 3.27Å; C174-Y233 VanDerWaalsContact N-O 3.12Å; C174-Y233 PolarHBondContact SG-O 3.22Å; C174-P248 HydrophobicContact CB-CB 4.26Å; C174-P248 WeakPolarHBondContact O-CB 3.5Å; C174-L249 VanDerWaalsContact SG-CA 3.56Å; C174-V252 HydrophobicContact CB-CB 4.47Å; C174-V252 HydrophobicContact CB-CG2 3.84Å
175	R	90.1	Very high	79	Confident	9 Å²	9	42.9 Å²	42.9	3%	0.034	22%	0.215	C	C	.	.	S	Bend	trans	-67.9	165	177.2	-62.5	-179.1	-64.7	148.9	7.4	111.2	D173 E179 S183 H190 D234 E235 L270	D173-R175 WeakPolarHBondContact OD1-CB 3.49Å; D173-R175 WeakPolarHBondContact OD1-CG 3.23Å; D173-R175 PolarHBondContact OD1-N 3.36Å; D173-R175 IonicContact OD1-NE 3Å; D173-R175 PolarHBondContact OD1-NE 3.45Å; D173-R175 IonicContact OD2-CZ 2.62Å; D173-R175 IonicContact OD2-NE 3.75Å; D173-R175 PolarHBondContact OD2-NE 2.85Å; D173-R175 VanDerWaalsContact OD2-NE 3.1Å; D173-R175 IonicContact OD2-NH2 3.54Å; D173-R175 PolarHBondContact OD2-NH2 3.03Å; R175-E179 HydrophobicContact CB-CB 4.06Å; R175-E179 PolarHBondContact NH2-O 3.4Å; R175-S183 PolarHBondContact NH2-O 2.93Å; R175-H190 PolarHBondContact O-NE2 2.67Å; R175-D234 HydrophobicContact CG-CB 4.35Å; R175-E235 WeakPolarHBondContact CD-OE2 3.33Å; R175-E235 HydrophobicContact CG-CB 4.42Å; R175-E235 IonicContact CZ-OE2 3.56Å; R175-E235 IonicContact NE-OE2 2.82Å; R175-E235 IonicContact NH1-OE2 3.01Å; R175-E235 PolarHBondContact NH1-OE2 3.49Å; R175-L270 VanDerWaalsContact CZ-CD2 3.43Å
176	P	80.1	Confident	80.9	Confident	48 Å²	48	37 Å²	37	31%	0.312	19%	0.188	S	C	.	.			trans	-50.9	143.6	169.8	-26.8	35.9	0	0	0	111.9	M178 E179 Y180	P176-M178 PolarHBondContact O-N 3.28Å; P176-E179 PolarHBondContact O-N 3.04Å; P176-Y180 PolarHBondContact O-N 2.51Å
177	F	75	Confident	82.2	Confident	30 Å²	30	35.3 Å²	35.3	13%	0.132	19%	0.194	C	C	.	.	H	α-helix	trans	-52.4	-34.1	-178	179.6	-116.3	0	0	0	112.5	Y180 N181 H190 Y434	F177-Y180 PolarHBondContact O-N 2.82Å; F177-N181 WeakPolarHBondContact CD2-ND2 3.27Å; F177-N181 VanDerWaalsContact CE1-ND2 3.27Å; F177-N181 WeakPolarHBondContact CE1-ND2 3.45Å; F177-N181 WeakPolarHBondContact CE2-ND2 3.35Å; F177-N181 WeakPolarHBondContact CZ-ND2 3.42Å; F177-N181 PolarHBondContact O-N 3.38Å; F177-N181 VanDerWaalsContact O-N 3.09Å; F177-N181 PolarHBondContact O-ND2 3.33Å; F177-H190 VanDerWaalsContact CA-CE1 3.48Å; F177-H190 WeakPolarHBondContact CA-CE1 3.4Å; F177-H190 AromaticContact CD2-CE1 3.83Å; F177-H190 AromaticContact CD2-ND1 3.64Å; F177-Y434 HydrophobicContact CE1-CD1 4.11Å; F177-Y434 HydrophobicContact CE1-CE1 4.18Å; F177-Y434 AromaticContact CZ-CD1 3.94Å; F177-Y434 HydrophobicContact CZ-CD1 3.94Å; F177-Y434 AromaticContact CZ-CE1 3.94Å; F177-Y434 HydrophobicContact CZ-CE1 3.94Å
178	M	68.6	Low	83.5	Confident	48 Å²	48	28.4 Å²	28.4	24%	0.236	16%	0.163	C	C	.	.	H	α-helix	trans	-64.6	-38.7	176.9	-64.7	-62.3	97.9	0	0	113.3	P176 K182 L448 M451	P176-M178 PolarHBondContact O-N 3.28Å; M178-K182 WeakPolarHBondContact O-CG 3.34Å; M178-K182 PolarHBondContact O-N 3.03Å; M178-L448 HydrophobicContact CB-CD2 3.92Å; M178-L448 HydrophobicContact CG-CD2 4.07Å; M178-L448 HydrophobicContact SD-CD2 4.09Å; M178-M451 HydrophobicContact CE-CE 3.65Å; M178-M451 HydrophobicContact CE-CG 4.32Å; M178-M451 HydrophobicContact CE-SD 4.4Å; M178-M451 HydrophobicContact SD-CB 3.71Å; M178-M451 HydrophobicContact SD-CE 4.09Å; M178-M451 HydrophobicContact SD-CG 3.57Å; M178-M451 VanDerWaalsContact SD-CG 3.57Å; M178-M451 HydrophobicContact SD-SD 4.4Å
179	E	78.6	Confident	84	Confident	66 Å²	66	28.6 Å²	28.6	31%	0.308	16%	0.16	S	C	.	.	H	α-helix	trans	-73.3	-38.5	179	-71.7	173.4	-154.6	0	0	111.5	R175 P176 N181 K182 S183	R175-E179 HydrophobicContact CB-CB 4.06Å; R175-E179 PolarHBondContact NH2-O 3.4Å; P176-E179 PolarHBondContact O-N 3.04Å; E179-N181 PolarHBondContact O-N 3.23Å; E179-K182 PolarHBondContact O-N 3.01Å; E179-S183 PolarHBondContact O-N 3.36Å
180	Y	80.4	Confident	84	Confident	32 Å²	32	27.8 Å²	27.8	13%	0.125	15%	0.154	C	C	.	.	H	α-helix	trans	-57.5	-47	171.9	174.5	-98.1	0	0	0	112.1	D173 P176 F177 K182 S183 H184 A188 H190	D173-Y180 HydrophobicContact CB-CD2 3.72Å; D173-Y180 HydrophobicContact CB-CE2 4.17Å; D173-Y180 WeakPolarHBondContact OD2-CD2 3.47Å; P176-Y180 PolarHBondContact O-N 2.51Å; F177-Y180 PolarHBondContact O-N 2.82Å; Y180-K182 VanDerWaalsContact C-N 3.35Å; Y180-K182 PolarHBondContact O-N 3.36Å; Y180-S183 CarbonylContact O-C 3.54Å; Y180-S183 VanDerWaalsContact O-C 3.31Å; Y180-S183 PolarHBondContact O-N 3.4Å; Y180-H184 HydrophobicContact CD2-CB 3.47Å; Y180-H184 VanDerWaalsContact CD2-CB 3.47Å; Y180-H184 AromaticContact CD2-CG 3.62Å; Y180-H184 AromaticContact CD2-ND1 3.96Å; Y180-H184 HydrophobicContact CE2-CB 3.64Å; Y180-H184 AromaticContact CE2-CD2 3.45Å; Y180-H184 VanDerWaalsContact CE2-CD2 3.45Å; Y180-H184 WeakPolarHBondContact CE2-CD2 3.39Å; Y180-H184 AromaticContact CE2-CG 3.37Å; Y180-H184 AromaticContact CE2-ND1 3.82Å; Y180-H184 AromaticContact CE2-NE2 3.94Å; Y180-H184 HydrophobicContact CG-CB 4.32Å; Y180-H184 AromaticContact CZ-CD2 3.75Å; Y180-H184 AromaticContact CZ-CE1 3.86Å; Y180-H184 AromaticContact CZ-CG 3.88Å; Y180-H184 AromaticContact CZ-ND1 3.94Å; Y180-H184 AromaticContact CZ-NE2 3.72Å; Y180-H184 PolarHBondContact O-ND1 2.95Å; Y180-A188 HydrophobicContact CE2-CB 4.44Å; Y180-A188 WeakPolarHBondContact CE2-O 3.34Å; Y180-A188 PolarHBondContact OH-O 3.22Å; Y180-H190 VanDerWaalsContact CB-CD2 3.46Å; Y180-H190 WeakPolarHBondContact CB-CD2 3.38Å; Y180-H190 HydrophobicContact CD1-CB 3.72Å; Y180-H190 AromaticContact CD1-CG 3.92Å; Y180-H190 HydrophobicContact CD2-CB 3.71Å; Y180-H190 AromaticContact CD2-CD2 3.89Å; Y180-H190 HydrophobicContact CE1-CB 3.71Å; Y180-H190 HydrophobicContact CE2-CB 3.7Å; Y180-H190 HydrophobicContact CG-CB 3.71Å; Y180-H190 AromaticContact CG-CD2 3.59Å; Y180-H190 AromaticContact CG-CG 3.72Å
181	N	73.7	Confident	83.8	Confident	24 Å²	24	27.3 Å²	27.3	13%	0.128	15%	0.151	C	C	.	.	H	α-helix	trans	-69.5	-29.4	-179.6	-78	-79.7	0	0	0	113.5	F177 E179 S284 Y434	F177-N181 WeakPolarHBondContact CD2-ND2 3.27Å; F177-N181 VanDerWaalsContact CE1-ND2 3.27Å; F177-N181 WeakPolarHBondContact CE1-ND2 3.45Å; F177-N181 WeakPolarHBondContact CE2-ND2 3.35Å; F177-N181 WeakPolarHBondContact CZ-ND2 3.42Å; F177-N181 PolarHBondContact O-N 3.38Å; F177-N181 VanDerWaalsContact O-N 3.09Å; F177-N181 PolarHBondContact O-ND2 3.33Å; E179-N181 PolarHBondContact O-N 3.23Å; N181-S284 WeakPolarHBondContact O-CB 3.49Å; N181-Y434 PolarHBondContact OD1-OH 3.47Å
182	K	77.2	Confident	82.9	Confident	93 Å²	93	29.3 Å²	29.3	40%	0.404	16%	0.162	S	C	.	.	H	α-helix	trans	-63.1	-49.5	173.7	-76.3	174.5	179	-175.9	0	110.6	M178 E179 Y180 S284 L285	M178-K182 WeakPolarHBondContact O-CG 3.34Å; M178-K182 PolarHBondContact O-N 3.03Å; E179-K182 PolarHBondContact O-N 3.01Å; Y180-K182 VanDerWaalsContact C-N 3.35Å; Y180-K182 PolarHBondContact O-N 3.36Å; K182-S284 PolarHBondContact O-N 3.38Å; K182-S284 VanDerWaalsContact O-N 3.12Å; K182-L285 HydrophobicContact CG-CD1 4.27Å
183	S	84.3	Confident	82.1	Confident	6 Å²	6	29.3 Å²	29.3	4%	0.042	16%	0.162	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-168.9	147.8	172.9	175	0	0	0	0	111.4	R175 E179 Y180 L270 K274 D282 N283	R175-S183 PolarHBondContact NH2-O 2.93Å; E179-S183 PolarHBondContact O-N 3.36Å; Y180-S183 CarbonylContact O-C 3.54Å; Y180-S183 VanDerWaalsContact O-C 3.31Å; Y180-S183 PolarHBondContact O-N 3.4Å; S183-L270 WeakPolarHBondContact O-CD2 3.3Å; S183-K274 WeakPolarHBondContact OG-CE 3.44Å; S183-K274 PolarHBondContact OG-NZ 3.27Å; S183-D282 CarbonylContact C-O 3.52Å; S183-D282 WeakPolarHBondContact CA-O 3.4Å; S183-D282 VanDerWaalsContact CB-O 3.25Å; S183-D282 WeakPolarHBondContact CB-O 3.47Å; S183-D282 PolarHBondContact OG-O 3.1Å; S183-N283 VanDerWaalsContact CB-OD1 3.22Å; S183-N283 WeakPolarHBondContact CB-OD1 3.25Å; S183-N283 PolarHBondContact OG-OD1 3.34Å
184	H	91.1	Very high	80.9	Confident	30 Å²	30	32 Å²	32	14%	0.139	18%	0.18	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-149.7	166.1	176.6	54.4	-83.3	0	0	0	110.5	Y180 Y233 C281 D282	Y180-H184 HydrophobicContact CD2-CB 3.47Å; Y180-H184 VanDerWaalsContact CD2-CB 3.47Å; Y180-H184 AromaticContact CD2-CG 3.62Å; Y180-H184 AromaticContact CD2-ND1 3.96Å; Y180-H184 HydrophobicContact CE2-CB 3.64Å; Y180-H184 AromaticContact CE2-CD2 3.45Å; Y180-H184 VanDerWaalsContact CE2-CD2 3.45Å; Y180-H184 WeakPolarHBondContact CE2-CD2 3.39Å; Y180-H184 AromaticContact CE2-CG 3.37Å; Y180-H184 AromaticContact CE2-ND1 3.82Å; Y180-H184 AromaticContact CE2-NE2 3.94Å; Y180-H184 HydrophobicContact CG-CB 4.32Å; Y180-H184 AromaticContact CZ-CD2 3.75Å; Y180-H184 AromaticContact CZ-CE1 3.86Å; Y180-H184 AromaticContact CZ-CG 3.88Å; Y180-H184 AromaticContact CZ-ND1 3.94Å; Y180-H184 AromaticContact CZ-NE2 3.72Å; Y180-H184 PolarHBondContact O-ND1 2.95Å; H184-Y233 WeakPolarHBondContact CB-OH 3.32Å; H184-C281 CarbonylContact O-C 3.59Å; H184-C281 VanDerWaalsContact O-CA 3.25Å; H184-C281 WeakPolarHBondContact O-CA 3.48Å; H184-D282 PolarHBondContact N-O 3Å; H184-D282 VanDerWaalsContact N-O 3.1Å; H184-D282 IonicContact NE2-OD2 3.57Å; H184-D282 PolarHBondContact O-N 3.38Å
185	I	91.9	Very high	79.6	Confident	0 Å²	0	34.2 Å²	34.2	0%	0	19%	0.192	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-65.3	135.4	172.3	-57.6	179.9	0	0	0	109.1	L152 M156 I171 G187 A188 Y233 L266 L270 F273	L152-I185 HydrophobicContact CD2-CD1 3.87Å; M156-I185 HydrophobicContact CE-CG2 3.56Å; M156-I185 HydrophobicContact SD-CG2 3.72Å; I171-I185 HydrophobicContact CD1-CG2 3.95Å; I185-G187 PolarHBondContact O-N 3.38Å; I185-A188 HydrophobicContact CB-CB 4.48Å; I185-A188 WeakPolarHBondContact O-CB 3.28Å; I185-A188 PolarHBondContact O-N 3.37Å; I185-Y233 HydrophobicContact CB-CE1 4.25Å; I185-Y233 HydrophobicContact CD1-CD1 4.08Å; I185-Y233 HydrophobicContact CD1-CD2 4.36Å; I185-Y233 HydrophobicContact CD1-CE1 3.92Å; I185-Y233 HydrophobicContact CD1-CE2 4.21Å; I185-Y233 HydrophobicContact CD1-CG 4.29Å; I185-Y233 HydrophobicContact CG1-CE1 4.14Å; I185-Y233 HydrophobicContact CG1-CE2 4.17Å; I185-Y233 PolarHBondContact N-OH 3.09Å; I185-L266 HydrophobicContact CD1-CD2 3.52Å; I185-L270 HydrophobicContact CD1-CD1 4.42Å; I185-L270 HydrophobicContact CG1-CD1 3.6Å; I185-F273 HydrophobicContact CD1-CB 4.37Å; I185-F273 HydrophobicContact CD1-CD1 3.84Å; I185-F273 HydrophobicContact CD1-CD2 4.2Å; I185-F273 HydrophobicContact CD1-CE1 4.13Å; I185-F273 HydrophobicContact CD1-CG 3.87Å; I185-F273 HydrophobicContact CD1-CZ 4.46Å; I185-F273 HydrophobicContact CG1-CD1 3.78Å; I185-F273 HydrophobicContact CG1-CE1 3.97Å; I185-F273 HydrophobicContact CG1-CG 4.32Å; I185-F273 HydrophobicContact CG2-CE1 4.05Å; I185-F273 HydrophobicContact CG2-CZ 4.25Å
186	Q	84.7	Confident	78.5	Confident	72 Å²	72	42.2 Å²	42.2	34%	0.336	23%	0.227	S	C	.	.	T	Hydrogen-bonded Turn	trans	-51.4	131.6	-179.3	-82.3	170	0.7	0	0	112.5	M156 A188 N279 L280 D282	M156-Q186 HydrophobicContact CE-CB 4.1Å; Q186-A188 PolarHBondContact O-N 3.01Å; Q186-N279 PolarHBondContact NE2-O 3.18Å; Q186-L280 WeakPolarHBondContact CB-O 3.39Å; Q186-L280 WeakPolarHBondContact CG-O 3.48Å; Q186-L280 PolarHBondContact N-O 2.94Å; Q186-D282 WeakPolarHBondContact CG-OD1 3.24Å; Q186-D282 PolarHBondContact NE2-OD1 2.94Å
187	G	79.3	Confident	77.9	Confident	67 Å²	67	45.7 Å²	45.7	69%	0.691	24%	0.242	S	C	*	.	T	Hydrogen-bonded Turn	trans	72.6	9	-179.8	0	0	0	0	0	115	I185	I185-G187 PolarHBondContact O-N 3.38Å
188	A	86.3	Confident	77.6	Confident	4 Å²	4	46.2 Å²	46.2	3%	0.033	25%	0.249	C	C	.	.	P	Polyproline II helix	trans	-70.8	134.6	175.7	0	0	0	0	0	112.3	I171 D173 Y180 I185 Q186 Y233	I171-A188 HydrophobicContact CB-CB 4.19Å; I171-A188 HydrophobicContact CG2-CB 3.89Å; I171-A188 CarbonylContact O-C 3.57Å; I171-A188 WeakPolarHBondContact O-CA 3.24Å; D173-A188 HydrophobicContact CB-CB 4.41Å; Y180-A188 HydrophobicContact CE2-CB 4.44Å; Y180-A188 WeakPolarHBondContact CE2-O 3.34Å; Y180-A188 PolarHBondContact OH-O 3.22Å; I185-A188 HydrophobicContact CB-CB 4.48Å; I185-A188 WeakPolarHBondContact O-CB 3.28Å; I185-A188 PolarHBondContact O-N 3.37Å; Q186-A188 PolarHBondContact O-N 3.01Å; A188-Y233 HydrophobicContact CB-CE1 3.93Å
189	V	83.4	Confident	78	Confident	22 Å²	22	46.4 Å²	46.4	13%	0.133	25%	0.247	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-87.4	120.7	172.7	-176.3	0	0	0	0	109.4	I171 I172 D173 I191 I213	I171-V189 PolarHBondContact O-N 2.84Å; I172-V189 WeakPolarHBondContact CA-O 3.29Å; D173-V189 PolarHBondContact N-O 3.18Å; V189-I191 HydrophobicContact CG1-CD1 4.47Å; V189-I213 HydrophobicContact CG1-CG1 4.16Å
190	H	85.9	Confident	77.7	Confident	8 Å²	8	51.3 Å²	51.3	4%	0.037	26%	0.263	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-79.1	129.1	175.7	-175.9	-106.7	0	0	0	112.5	R175 F177 Y180 R216	R175-H190 PolarHBondContact O-NE2 2.67Å; F177-H190 VanDerWaalsContact CA-CE1 3.48Å; F177-H190 WeakPolarHBondContact CA-CE1 3.4Å; F177-H190 AromaticContact CD2-CE1 3.83Å; F177-H190 AromaticContact CD2-ND1 3.64Å; Y180-H190 VanDerWaalsContact CB-CD2 3.46Å; Y180-H190 WeakPolarHBondContact CB-CD2 3.38Å; Y180-H190 HydrophobicContact CD1-CB 3.72Å; Y180-H190 AromaticContact CD1-CG 3.92Å; Y180-H190 HydrophobicContact CD2-CB 3.71Å; Y180-H190 AromaticContact CD2-CD2 3.89Å; Y180-H190 HydrophobicContact CE1-CB 3.71Å; Y180-H190 HydrophobicContact CE2-CB 3.7Å; Y180-H190 HydrophobicContact CG-CB 3.71Å; Y180-H190 AromaticContact CG-CD2 3.59Å; Y180-H190 AromaticContact CG-CG 3.72Å; H190-R216 PolarHBondContact O-NH2 3.45Å
191	I	82.3	Confident	77.5	Confident	4 Å²	4	55.4 Å²	55.4	2%	0.021	28%	0.278	C	S	.	.			trans	-115.9	114.6	172.4	-60	-65.6	0	0	0	109.1	I172 D173 V189 C193 L202 V209 L212 I213 V252	I172-I191 HydrophobicContact CG2-CB 4.27Å; I172-I191 HydrophobicContact CG2-CG1 3.68Å; D173-I191 PolarHBondContact O-N 2.86Å; V189-I191 HydrophobicContact CG1-CD1 4.47Å; I191-C193 PolarHBondContact O-N 3Å; I191-L202 HydrophobicContact CG2-CD1 4.48Å; I191-V209 HydrophobicContact CD1-CG1 4.33Å; I191-V209 HydrophobicContact CG1-CG1 4.27Å; I191-L212 HydrophobicContact CD1-CB 3.84Å; I191-L212 HydrophobicContact CD1-CD1 4.19Å; I191-L212 HydrophobicContact CG2-CD1 4.21Å; I191-I213 HydrophobicContact CD1-CG1 4.27Å; I191-V252 HydrophobicContact CG2-CG2 4.11Å
192	N	72.8	Confident	77.8	Confident	52 Å²	52	54.3 Å²	54.3	28%	0.278	27%	0.272	S	S	.	.			trans	-79.6	111.8	178.9	-172.4	10.2	0	0	0	111.2	S194 D195	N192-S194 WeakPolarHBondContact OD1-CB 3.3Å; N192-S194 PolarHBondContact OD1-N 3Å; N192-D195 PolarHBondContact ND2-OD1 2.91Å
193	C	75.1	Confident	78.1	Confident	0 Å²	0	53.5 Å²	53.5	0%	0	27%	0.27	C	S	.	.			trans	-112.9	9.5	169.5	-56.7	0	0	0	0	112.7	I191 R199 P248 V252	I191-C193 PolarHBondContact O-N 3Å; C193-R199 PolarHBondContact O-NE 3.35Å; C193-R199 PolarHBondContact O-NH2 2.98Å; C193-P248 HydrophobicContact CB-CB 3.9Å; C193-P248 HydrophobicContact CB-CG 4.39Å; C193-V252 VanDerWaalsContact SG-CG2 3.57Å
194	S	66.3	Low	78	Confident	55 Å²	55	58.4 Å²	58.4	39%	0.385	29%	0.292	S	S	.	.	S	Bend	trans	-77.9	-32.7	-177	-57.6	0	0	0	0	111.8	N192	N192-S194 WeakPolarHBondContact OD1-CB 3.3Å; N192-S194 PolarHBondContact OD1-N 3Å
195	D	64.8	Low	77.5	Confident	49 Å²	49	58.7 Å²	58.7	26%	0.262	30%	0.303	S	S	.	.	S	Bend	trans	-79.2	144.3	178.9	78.4	-89.1	0	0	0	112.1	N192 I197 S198 R199	N192-D195 PolarHBondContact ND2-OD1 2.91Å; D195-I197 PolarHBondContact O-N 2.97Å; D195-I197 PolarHBondContact OD2-N 3.42Å; D195-I197 VanDerWaalsContact OD2-N 3.1Å; D195-S198 WeakPolarHBondContact OD1-CB 3.49Å; D195-S198 PolarHBondContact OD1-OG 3.13Å; D195-S198 WeakPolarHBondContact OD2-CB 3.28Å; D195-S198 PolarHBondContact OD2-N 3.29Å; D195-S198 PolarHBondContact OD2-OG 3.41Å; D195-R199 WeakPolarHBondContact O-CB 3.17Å; D195-R199 PolarHBondContact O-N 2.87Å
196	K	66.4	Low	76.7	Confident	176 Å²	176	65.6 Å²	65.6	77%	0.765	33%	0.333	S	S	*	.	H	α-helix	trans	-65.2	-25.7	-175.4	-71	179.6	-179	171.3	0	112.9	R200	K196-R200 WeakPolarHBondContact O-CB 3.31Å; K196-R200 WeakPolarHBondContact O-CG 3.48Å; K196-R200 PolarHBondContact O-N 3.5Å
197	I	67.7	Low	76.4	Confident	122 Å²	122	63.7 Å²	63.7	63%	0.626	33%	0.325	S	S	*	.	H	α-helix	trans	-81	-57.3	-172.7	-61.8	174.4	0	0	0	109.9	D195 R199 R200 R201	D195-I197 PolarHBondContact O-N 2.97Å; D195-I197 PolarHBondContact OD2-N 3.42Å; D195-I197 VanDerWaalsContact OD2-N 3.1Å; I197-R199 VanDerWaalsContact C-N 3.27Å; I197-R199 PolarHBondContact O-N 3.16Å; I197-R200 PolarHBondContact O-N 3.26Å; I197-R201 WeakPolarHBondContact O-CG 3.46Å; I197-R201 PolarHBondContact O-N 2.92Å
198	S	68.2	Low	76.5	Confident	40 Å²	40	61.6 Å²	61.6	28%	0.28	30%	0.299	S	S	.	.	H	α-helix	trans	-57.5	-42.6	176.3	-52.7	0	0	0	0	110.8	D195 R200 R201 L202	D195-S198 WeakPolarHBondContact OD1-CB 3.49Å; D195-S198 PolarHBondContact OD1-OG 3.13Å; D195-S198 WeakPolarHBondContact OD2-CB 3.28Å; D195-S198 PolarHBondContact OD2-N 3.29Å; D195-S198 PolarHBondContact OD2-OG 3.41Å; S198-R200 PolarHBondContact O-N 3.08Å; S198-R201 PolarHBondContact O-N 2.97Å; S198-L202 WeakPolarHBondContact O-CB 3.39Å; S198-L202 WeakPolarHBondContact O-CG 3.41Å; S198-L202 PolarHBondContact O-N 3.17Å
199	R	76.9	Confident	76.2	Confident	53 Å²	53	61.4 Å²	61.4	20%	0.2	30%	0.297	C	S	.	.	H	α-helix	trans	-55.1	-53.2	173.9	-176.9	-177.3	-69.7	-113	0.3	112.4	C193 D195 I197 R201 L202 Q203 S246 I251	C193-R199 PolarHBondContact O-NE 3.35Å; C193-R199 PolarHBondContact O-NH2 2.98Å; D195-R199 WeakPolarHBondContact O-CB 3.17Å; D195-R199 PolarHBondContact O-N 2.87Å; I197-R199 VanDerWaalsContact C-N 3.27Å; I197-R199 PolarHBondContact O-N 3.16Å; R199-R201 VanDerWaalsContact C-N 3.32Å; R199-R201 PolarHBondContact O-N 3.43Å; R199-L202 PolarHBondContact O-N 3.42Å; R199-Q203 WeakPolarHBondContact O-CB 3.32Å; R199-Q203 VanDerWaalsContact O-CG 3.28Å; R199-Q203 WeakPolarHBondContact O-CG 3.33Å; R199-Q203 PolarHBondContact O-N 3.38Å; R199-S246 PolarHBondContact NH1-O 3.36Å; R199-I251 HydrophobicContact CG-CD1 3.58Å
200	R	73.8	Confident	76	Confident	168 Å²	168	60.4 Å²	60.4	63%	0.634	29%	0.291	S	S	*	.	H	α-helix	trans	-62.1	-40.4	178.3	-84.7	-178.1	176.2	-179.3	-0.3	111.6	K196 I197 S198 Q203 Q204	K196-R200 WeakPolarHBondContact O-CB 3.31Å; K196-R200 WeakPolarHBondContact O-CG 3.48Å; K196-R200 PolarHBondContact O-N 3.5Å; I197-R200 PolarHBondContact O-N 3.26Å; S198-R200 PolarHBondContact O-N 3.08Å; R200-Q203 PolarHBondContact O-N 2.79Å; R200-Q204 VanDerWaalsContact O-CB 3.22Å; R200-Q204 WeakPolarHBondContact O-CB 3.28Å; R200-Q204 WeakPolarHBondContact O-CG 3.32Å; R200-Q204 PolarHBondContact O-N 3.27Å
201	R	75.8	Confident	75.3	Confident	119 Å²	119	63.2 Å²	63.2	45%	0.449	31%	0.306	S	S	.	.	H	α-helix	trans	-65.8	-41.4	-179.8	-68.7	176.8	68.5	179.1	1.4	112.1	I197 S198 R199 G205 K206 I207	I197-R201 WeakPolarHBondContact O-CG 3.46Å; I197-R201 PolarHBondContact O-N 2.92Å; S198-R201 PolarHBondContact O-N 2.97Å; R199-R201 VanDerWaalsContact C-N 3.32Å; R199-R201 PolarHBondContact O-N 3.43Å; R201-G205 PolarHBondContact O-N 3.23Å; R201-G205 VanDerWaalsContact O-N 3.13Å; R201-K206 HydrophobicContact CB-CB 4.39Å; R201-K206 PolarHBondContact O-N 3.21Å; R201-I207 HydrophobicContact CB-CG2 3.57Å; R201-I207 PolarHBondContact O-N 3.42Å
202	L	80.6	Confident	74.7	Confident	1 Å²	1	65.5 Å²	65.5	1%	0.005	32%	0.319	C	S	.	.	H	α-helix	trans	-66.5	-44.3	175.1	-76.2	166.1	0	0	0	112.1	I191 S198 R199 Q204 G205 I207 V209 L212 I251 R258	I191-L202 HydrophobicContact CG2-CD1 4.48Å; S198-L202 WeakPolarHBondContact O-CB 3.39Å; S198-L202 WeakPolarHBondContact O-CG 3.41Å; S198-L202 PolarHBondContact O-N 3.17Å; R199-L202 PolarHBondContact O-N 3.42Å; L202-Q204 VanDerWaalsContact C-N 3.33Å; L202-Q204 PolarHBondContact O-N 3.04Å; L202-G205 PolarHBondContact O-N 2.81Å; L202-G205 VanDerWaalsContact O-N 3.16Å; L202-I207 HydrophobicContact CD2-CG2 4.09Å; L202-I207 HydrophobicContact CG-CG2 4.05Å; L202-V209 HydrophobicContact CD2-CG2 3.98Å; L202-L212 HydrophobicContact CD2-CD1 4.18Å; L202-I251 HydrophobicContact CB-CG2 4.03Å; L202-R258 PolarHBondContact O-NH1 3.45Å
203	Q	82.3	Confident	74.6	Confident	76 Å²	76	63.1 Å²	63.1	36%	0.355	31%	0.306	S	S	.	.	H	α-helix	trans	-63.4	-39.5	176.7	-73.7	177	-36.7	0	0	112	R199 R200 G205 I251 R258	R199-Q203 WeakPolarHBondContact O-CB 3.32Å; R199-Q203 VanDerWaalsContact O-CG 3.28Å; R199-Q203 WeakPolarHBondContact O-CG 3.33Å; R199-Q203 PolarHBondContact O-N 3.38Å; R200-Q203 PolarHBondContact O-N 2.79Å; Q203-G205 VanDerWaalsContact C-N 3.25Å; Q203-G205 PolarHBondContact O-N 2.83Å; Q203-I251 HydrophobicContact CG-CD1 4.34Å; Q203-I251 HydrophobicContact CG-CG1 4.35Å; Q203-I251 HydrophobicContact CG-CG2 3.99Å; Q203-R258 PolarHBondContact O-NH2 2.5Å
204	Q	82.6	Confident	74.1	Confident	108 Å²	108	63.8 Å²	63.8	51%	0.505	31%	0.31	S	S	.	.	T	Hydrogen-bonded Turn	trans	-77.8	-6.3	177.1	-69	171.9	6.9	0	0	113.5	R200 L202 K206	R200-Q204 VanDerWaalsContact O-CB 3.22Å; R200-Q204 WeakPolarHBondContact O-CB 3.28Å; R200-Q204 WeakPolarHBondContact O-CG 3.32Å; R200-Q204 PolarHBondContact O-N 3.27Å; L202-Q204 VanDerWaalsContact C-N 3.33Å; L202-Q204 PolarHBondContact O-N 3.04Å; Q204-K206 HydrophobicContact CB-CD 4.32Å; Q204-K206 HydrophobicContact CB-CG 4.06Å; Q204-K206 PolarHBondContact O-N 3Å
205	G	80.9	Confident	73.4	Confident	36 Å²	36	66.7 Å²	66.7	37%	0.371	33%	0.329	S	S	.	.	T	Hydrogen-bonded Turn	trans	66	20.3	-175.3	0	0	0	0	0	114.2	R201 L202 Q203 I207	R201-G205 PolarHBondContact O-N 3.23Å; R201-G205 VanDerWaalsContact O-N 3.13Å; L202-G205 PolarHBondContact O-N 2.81Å; L202-G205 VanDerWaalsContact O-N 3.16Å; Q203-G205 VanDerWaalsContact C-N 3.25Å; Q203-G205 PolarHBondContact O-N 2.83Å; G205-I207 VanDerWaalsContact C-N 3.3Å
206	K	75.8	Confident	72.9	Confident	146 Å²	146	71 Å²	71	64%	0.635	34%	0.342	S	S	*	.	S	Bend	trans	-78	-17.9	176	-71.6	-178.4	175.7	166.3	0	113.1	R201 Q204	R201-K206 HydrophobicContact CB-CB 4.39Å; R201-K206 PolarHBondContact O-N 3.21Å; Q204-K206 HydrophobicContact CB-CD 4.32Å; Q204-K206 HydrophobicContact CB-CG 4.06Å; Q204-K206 PolarHBondContact O-N 3Å
207	I	76.8	Confident	72.1	Confident	31 Å²	31	67 Å²	67	16%	0.159	33%	0.326	C	S	.	.	S	Bend	trans	-145.4	144.2	170.5	-168	167.7	0	0	0	106.3	R201 L202 G205 D211 L212	R201-I207 HydrophobicContact CB-CG2 3.57Å; R201-I207 PolarHBondContact O-N 3.42Å; L202-I207 HydrophobicContact CD2-CG2 4.09Å; L202-I207 HydrophobicContact CG-CG2 4.05Å; G205-I207 VanDerWaalsContact C-N 3.3Å; I207-D211 HydrophobicContact CG1-CB 4.21Å; I207-L212 HydrophobicContact CD1-CD2 3.54Å; I207-L212 HydrophobicContact CD1-CG 3.98Å; I207-L212 HydrophobicContact CG1-CD2 4.34Å; I207-L212 HydrophobicContact CG1-CG 4.25Å
208	T	81.6	Confident	71.1	Confident	24 Å²	24	63.2 Å²	63.2	15%	0.147	32%	0.317	C	S	.	.			trans	-109.1	165.3	178.2	83.6	0	0	0	0	112.4	L210 D211 L212 E259	T208-L210 VanDerWaalsContact C-N 3.28Å; T208-L210 PolarHBondContact OG1-N 2.97Å; T208-D211 PolarHBondContact N-OD2 3.18Å; T208-D211 PolarHBondContact O-N 3.28Å; T208-D211 VanDerWaalsContact OG1-CG 3.29Å; T208-D211 PolarHBondContact OG1-N 3.05Å; T208-D211 VanDerWaalsContact OG1-N 3.08Å; T208-D211 PolarHBondContact OG1-OD2 3.28Å; T208-L212 WeakPolarHBondContact O-CG 3.3Å; T208-L212 PolarHBondContact O-N 2.71Å; T208-E259 WeakPolarHBondContact CB-OE1 3.34Å; T208-E259 VanDerWaalsContact CB-OE2 3.29Å; T208-E259 WeakPolarHBondContact CB-OE2 3.24Å; T208-E259 HydrophobicContact CG2-CG 4.24Å; T208-E259 WeakPolarHBondContact CG2-OE1 3.36Å; T208-E259 VanDerWaalsContact OG1-CD 3.28Å; T208-E259 PolarHBondContact OG1-OE1 3.42Å; T208-E259 PolarHBondContact OG1-OE2 3.28Å
209	V	80.4	Confident	69.9	Low	0 Å²	0	70.9 Å²	70.9	0%	0	35%	0.345	C	S	.	.	H	α-helix	trans	-65.2	-37.1	174.1	172.3	0	0	0	0	110.1	I172 I191 L202 L212 I213 V252 S255 L256	I172-V209 HydrophobicContact CD1-CG1 3.86Å; I191-V209 HydrophobicContact CD1-CG1 4.33Å; I191-V209 HydrophobicContact CG1-CG1 4.27Å; L202-V209 HydrophobicContact CD2-CG2 3.98Å; V209-L212 PolarHBondContact O-N 3.46Å; V209-I213 HydrophobicContact CG1-CD1 3.8Å; V209-I213 HydrophobicContact CG1-CG1 4.46Å; V209-I213 VanDerWaalsContact O-CG1 3.27Å; V209-I213 WeakPolarHBondContact O-CG1 3.33Å; V209-I213 PolarHBondContact O-N 2.94Å; V209-I213 VanDerWaalsContact O-N 3.08Å; V209-V252 HydrophobicContact CG2-CG1 4.18Å; V209-S255 PolarHBondContact N-OG 2.82Å; V209-L256 HydrophobicContact CB-CD2 3.92Å; V209-L256 HydrophobicContact CB-CG 4.19Å; V209-L256 HydrophobicContact CG1-CD2 3.82Å; V209-L256 HydrophobicContact CG1-CG 4.19Å; V209-L256 HydrophobicContact CG2-CG 4.46Å
210	L	78.9	Confident	68.5	Low	0 Å²	0	75.3 Å²	75.3	0%	0	37%	0.373	C	S	.	.	H	α-helix	trans	-67.6	-35.4	177.5	-62.5	179.4	0	0	0	112.3	T208 L212 I213 S214 I225 F226 I230 L256 E259 K261	T208-L210 VanDerWaalsContact C-N 3.28Å; T208-L210 PolarHBondContact OG1-N 2.97Å; L210-L212 VanDerWaalsContact C-N 3.34Å; L210-I213 HydrophobicContact CD2-CD1 4.46Å; L210-I213 PolarHBondContact O-N 2.57Å; L210-S214 WeakPolarHBondContact O-CB 3.46Å; L210-S214 PolarHBondContact O-N 3.3Å; L210-S214 PolarHBondContact O-OG 2.92Å; L210-I225 HydrophobicContact CD2-CG2 4.04Å; L210-F226 HydrophobicContact CB-CZ 4.47Å; L210-F226 HydrophobicContact CD1-CD1 4.38Å; L210-F226 HydrophobicContact CD1-CE1 3.68Å; L210-F226 HydrophobicContact CD1-CE2 4.06Å; L210-F226 HydrophobicContact CD1-CZ 3.52Å; L210-I230 HydrophobicContact CD2-CD1 4.19Å; L210-L256 HydrophobicContact CD2-CD2 4.24Å; L210-L256 HydrophobicContact CG-CD2 4.41Å; L210-E259 HydrophobicContact CD1-CB 4.19Å; L210-E259 WeakPolarHBondContact CG-OE2 3.37Å; L210-K261 HydrophobicContact CD1-CG 4.21Å
211	D	71.4	Confident	67.5	Low	67 Å²	67	68.5 Å²	68.5	36%	0.358	35%	0.351	S	S	.	.	H	α-helix	trans	-59.4	-46.4	172.5	-66.2	-30.9	0	0	0	111	I207 T208 I213 S214 C215	I207-D211 HydrophobicContact CG1-CB 4.21Å; T208-D211 PolarHBondContact N-OD2 3.18Å; T208-D211 PolarHBondContact O-N 3.28Å; T208-D211 VanDerWaalsContact OG1-CG 3.29Å; T208-D211 PolarHBondContact OG1-N 3.05Å; T208-D211 VanDerWaalsContact OG1-N 3.08Å; T208-D211 PolarHBondContact OG1-OD2 3.28Å; D211-I213 VanDerWaalsContact C-N 3.32Å; D211-I213 PolarHBondContact O-N 2.74Å; D211-S214 PolarHBondContact O-N 3.42Å; D211-C215 PolarHBondContact O-N 2.92Å; D211-C215 PolarHBondContact O-SG 3.24Å
212	L	70.8	Confident	66.3	Low	53 Å²	53	66.9 Å²	66.9	28%	0.277	35%	0.347	S	S	.	.	H	α-helix	trans	-64.1	-35.3	-179.8	-70.4	172.9	0	0	0	113	I191 L202 I207 T208 V209 L210	I191-L212 HydrophobicContact CD1-CB 3.84Å; I191-L212 HydrophobicContact CD1-CD1 4.19Å; I191-L212 HydrophobicContact CG2-CD1 4.21Å; L202-L212 HydrophobicContact CD2-CD1 4.18Å; I207-L212 HydrophobicContact CD1-CD2 3.54Å; I207-L212 HydrophobicContact CD1-CG 3.98Å; I207-L212 HydrophobicContact CG1-CD2 4.34Å; I207-L212 HydrophobicContact CG1-CG 4.25Å; T208-L212 WeakPolarHBondContact O-CG 3.3Å; T208-L212 PolarHBondContact O-N 2.71Å; V209-L212 PolarHBondContact O-N 3.46Å; L210-L212 VanDerWaalsContact C-N 3.34Å
213	I	69.8	Low	65	Low	1 Å²	1	75.4 Å²	75.4	1%	0.005	38%	0.384	C	S	.	.	H	α-helix	trans	-73.4	-43.9	175.5	-63.5	164.9	0	0	0	109.9	V170 I172 V189 I191 V209 L210 D211 C215 R216 I225	V170-I213 HydrophobicContact CG1-CD1 4.41Å; I172-I213 HydrophobicContact CD1-CD1 3.77Å; I172-I213 HydrophobicContact CG1-CD1 4.27Å; V189-I213 HydrophobicContact CG1-CG1 4.16Å; I191-I213 HydrophobicContact CD1-CG1 4.27Å; V209-I213 HydrophobicContact CG1-CD1 3.8Å; V209-I213 HydrophobicContact CG1-CG1 4.46Å; V209-I213 VanDerWaalsContact O-CG1 3.27Å; V209-I213 WeakPolarHBondContact O-CG1 3.33Å; V209-I213 PolarHBondContact O-N 2.94Å; V209-I213 VanDerWaalsContact O-N 3.08Å; L210-I213 HydrophobicContact CD2-CD1 4.46Å; L210-I213 PolarHBondContact O-N 2.57Å; D211-I213 VanDerWaalsContact C-N 3.32Å; D211-I213 PolarHBondContact O-N 2.74Å; I213-C215 PolarHBondContact O-N 3.37Å; I213-R216 WeakPolarHBondContact O-CB 3.44Å; I213-R216 PolarHBondContact O-N 3.41Å; I213-I225 HydrophobicContact CG2-CD1 3.84Å; I213-I225 HydrophobicContact CG2-CG1 4.49Å
214	S	63.6	Low	64	Low	14 Å²	14	77.9 Å²	77.9	10%	0.098	39%	0.391	C	S	.	.	H	α-helix	trans	-68.2	-33.9	-174.9	-64.3	0	0	0	0	113.9	L210 D211 R216 E217 G218 F222	L210-S214 WeakPolarHBondContact O-CB 3.46Å; L210-S214 PolarHBondContact O-N 3.3Å; L210-S214 PolarHBondContact O-OG 2.92Å; D211-S214 PolarHBondContact O-N 3.42Å; S214-R216 PolarHBondContact O-N 3.16Å; S214-R216 VanDerWaalsContact O-N 3.14Å; S214-E217 PolarHBondContact O-N 2.84Å; S214-G218 PolarHBondContact O-N 2.84Å; S214-F222 VanDerWaalsContact CB-CD2 3.44Å; S214-F222 WeakPolarHBondContact OG-CD2 3.47Å; S214-F222 WeakPolarHBondContact OG-CE2 3.32Å
215	C	51.8	Low	63.1	Low	116 Å²	116	72.8 Å²	72.8	78%	0.784	37%	0.367	S	S	*	.	H	α-helix	trans	-57.6	-23	171.6	-74.1	0	0	0	0	112.8	D211 I213	D211-C215 PolarHBondContact O-N 2.92Å; D211-C215 PolarHBondContact O-SG 3.24Å; I213-C215 PolarHBondContact O-N 3.37Å
216	R	54.8	Low	62.4	Low	141 Å²	141	74.7 Å²	74.7	53%	0.532	37%	0.365	S	S	.	.	H	α-helix	trans	-90.2	-26.9	179.5	-62.4	-171.1	-177.6	-169.1	7.6	114.1	H190 I213 S214	H190-R216 PolarHBondContact O-NH2 3.45Å; I213-R216 WeakPolarHBondContact O-CB 3.44Å; I213-R216 PolarHBondContact O-N 3.41Å; S214-R216 PolarHBondContact O-N 3.16Å; S214-R216 VanDerWaalsContact O-N 3.14Å
217	E	49.8	Very low	62	Low	92 Å²	92	73 Å²	73	43%	0.43	37%	0.372	S	S	.	.	H	α-helix	trans	-109.6	-3.7	-169.9	-61.6	-164.7	157.5	0	0	115.3	S214 S221 I225	S214-E217 PolarHBondContact O-N 2.84Å; E217-S221 VanDerWaalsContact CB-CB 3.46Å; E217-S221 VanDerWaalsContact O-CB 3.27Å; E217-S221 WeakPolarHBondContact O-CB 3.26Å; E217-S221 PolarHBondContact O-OG 3.28Å; E217-I225 WeakPolarHBondContact OE2-CD1 3.44Å
218	G	46.2	Very low	61.9	Low	42 Å²	42	73.5 Å²	73.5	43%	0.433	37%	0.373	S	S	.	.			trans	79.3	169.3	177.2	0	0	0	0	0	115.2	S214 D220 S221	S214-G218 PolarHBondContact O-N 2.84Å; G218-D220 PolarHBondContact O-N 3.1Å; G218-S221 PolarHBondContact O-N 3.31Å
219	K	43.2	Very low	62.2	Low	200 Å²	200	76 Å²	76	87%	0.87	38%	0.383	S	S	*	.	H	α-helix	trans	-62.5	-31.8	-168.5	-72.8	-177.2	177.6	176.8	0	115.1	F222	K219-F222 WeakPolarHBondContact O-CB 3.13Å
220	D	46.9	Very low	62.7	Low	146 Å²	146	76.4 Å²	76.4	78%	0.781	39%	0.385	S	S	*	.	H	α-helix	trans	-80	-21.6	-179.1	-68.4	-37.4	0	0	0	113.5	G218	G218-D220 PolarHBondContact O-N 3.1Å
221	S	52.8	Low	63.4	Low	26 Å²	26	76.4 Å²	76.4	18%	0.182	39%	0.385	C	S	.	.	H	α-helix	trans	-79.3	-22.3	175.2	-56.9	0	0	0	0	112.3	E217 G218 K223 R224 I225	E217-S221 VanDerWaalsContact CB-CB 3.46Å; E217-S221 VanDerWaalsContact O-CB 3.27Å; E217-S221 WeakPolarHBondContact O-CB 3.26Å; E217-S221 PolarHBondContact O-OG 3.28Å; G218-S221 PolarHBondContact O-N 3.31Å; S221-K223 PolarHBondContact O-N 3.3Å; S221-R224 WeakPolarHBondContact O-CB 3.1Å; S221-R224 PolarHBondContact O-N 3.48Å; S221-I225 WeakPolarHBondContact O-CG1 3.32Å; S221-I225 PolarHBondContact O-N 3.02Å
222	F	51.5	Low	64.6	Low	84 Å²	84	73.2 Å²	73.2	37%	0.368	37%	0.368	S	S	.	.	H	α-helix	trans	-53.2	-53.3	-179.3	-163.7	-91.2	0	0	0	112.1	S214 K219 R224 I225 F226	S214-F222 VanDerWaalsContact CB-CD2 3.44Å; S214-F222 WeakPolarHBondContact OG-CD2 3.47Å; S214-F222 WeakPolarHBondContact OG-CE2 3.32Å; K219-F222 WeakPolarHBondContact O-CB 3.13Å; F222-R224 PolarHBondContact O-N 3Å; F222-I225 PolarHBondContact O-N 3.17Å; F222-F226 HydrophobicContact CD1-CD2 4.32Å; F222-F226 AromaticContact CD1-CE2 3.83Å; F222-F226 HydrophobicContact CD1-CE2 3.83Å; F222-F226 HydrophobicContact CE1-CD2 4.23Å; F222-F226 AromaticContact CE1-CE2 3.37Å; F222-F226 HydrophobicContact CE1-CE2 3.37Å; F222-F226 AromaticContact CE1-CZ 3.8Å; F222-F226 HydrophobicContact CE1-CZ 3.8Å; F222-F226 HydrophobicContact CE2-CE2 4.18Å; F222-F226 HydrophobicContact CG-CE2 4.41Å; F222-F226 AromaticContact CZ-CE2 3.57Å; F222-F226 HydrophobicContact CZ-CE2 3.57Å; F222-F226 AromaticContact CZ-CZ 3.85Å; F222-F226 HydrophobicContact CZ-CZ 3.85Å; F222-F226 WeakPolarHBondContact O-CD2 3.34Å
223	K	54.3	Low	65.8	Low	180 Å²	180	70.7 Å²	70.7	78%	0.783	35%	0.354	S	S	*	.	H	α-helix	trans	-65.7	-24.9	179.9	-69.3	-177.1	179.9	177.7	0	113.1	S221	S221-K223 PolarHBondContact O-N 3.3Å
224	R	60.3	Low	66.9	Low	128 Å²	128	71.5 Å²	71.5	48%	0.483	36%	0.359	S	S	.	.	H	α-helix	trans	-80.3	-36.5	-177.2	-162.3	-178.2	-60.7	165.1	3.5	112.1	S221 F222 F226 S227 K228	S221-R224 WeakPolarHBondContact O-CB 3.1Å; S221-R224 PolarHBondContact O-N 3.48Å; F222-R224 PolarHBondContact O-N 3Å; R224-F226 VanDerWaalsContact C-N 3.28Å; R224-F226 PolarHBondContact O-N 3.11Å; R224-S227 PolarHBondContact O-N 2.79Å; R224-K228 WeakPolarHBondContact O-CG 3.46Å
225	I	63.9	Low	68.3	Low	1 Å²	1	73.4 Å²	73.4	1%	0.005	37%	0.366	C	S	.	.	H	α-helix	trans	-61.8	-37.8	176.4	-65.9	157.7	0	0	0	110.7	V170 L210 I213 E217 S221 F222 S227 K228	V170-I225 HydrophobicContact CG2-CG2 4.46Å; L210-I225 HydrophobicContact CD2-CG2 4.04Å; I213-I225 HydrophobicContact CG2-CD1 3.84Å; I213-I225 HydrophobicContact CG2-CG1 4.49Å; E217-I225 WeakPolarHBondContact OE2-CD1 3.44Å; S221-I225 WeakPolarHBondContact O-CG1 3.32Å; S221-I225 PolarHBondContact O-N 3.02Å; F222-I225 PolarHBondContact O-N 3.17Å; I225-S227 PolarHBondContact O-N 2.79Å; I225-K228 PolarHBondContact O-N 2.94Å; I225-K228 VanDerWaalsContact O-N 3.16Å
226	F	65	Low	70.2	Confident	77 Å²	77	72.5 Å²	72.5	34%	0.338	35%	0.354	S	S	.	.	T	Hydrogen-bonded Turn	trans	-66.2	-22.5	-177.7	-81.8	-108.8	0	0	0	113.8	L210 F222 R224 K261	L210-F226 HydrophobicContact CB-CZ 4.47Å; L210-F226 HydrophobicContact CD1-CD1 4.38Å; L210-F226 HydrophobicContact CD1-CE1 3.68Å; L210-F226 HydrophobicContact CD1-CE2 4.06Å; L210-F226 HydrophobicContact CD1-CZ 3.52Å; F222-F226 HydrophobicContact CD1-CD2 4.32Å; F222-F226 AromaticContact CD1-CE2 3.83Å; F222-F226 HydrophobicContact CD1-CE2 3.83Å; F222-F226 HydrophobicContact CE1-CD2 4.23Å; F222-F226 AromaticContact CE1-CE2 3.37Å; F222-F226 HydrophobicContact CE1-CE2 3.37Å; F222-F226 AromaticContact CE1-CZ 3.8Å; F222-F226 HydrophobicContact CE1-CZ 3.8Å; F222-F226 HydrophobicContact CE2-CE2 4.18Å; F222-F226 HydrophobicContact CG-CE2 4.41Å; F222-F226 AromaticContact CZ-CE2 3.57Å; F222-F226 HydrophobicContact CZ-CE2 3.57Å; F222-F226 AromaticContact CZ-CZ 3.85Å; F222-F226 HydrophobicContact CZ-CZ 3.85Å; F222-F226 WeakPolarHBondContact O-CD2 3.34Å; R224-F226 VanDerWaalsContact C-N 3.28Å; R224-F226 PolarHBondContact O-N 3.11Å; F226-K261 VanDerWaalsContact CA-NZ 3.32Å; F226-K261 PolarHBondContact O-NZ 2.98Å
227	S	67.6	Low	72	Confident	111 Å²	111	66.6 Å²	66.6	78%	0.776	33%	0.333	S	S	*	.	T	Hydrogen-bonded Turn	trans	-95	-6.7	178.7	-55.5	0	0	0	0	113.5	R224 I225	R224-S227 PolarHBondContact O-N 2.79Å; I225-S227 PolarHBondContact O-N 2.79Å
228	K	76.3	Confident	73.9	Confident	41 Å²	41	66.9 Å²	66.9	18%	0.178	34%	0.338	C	S	.	.	S	Bend	trans	-89.2	146.6	-179.1	-74.6	178.4	172	-168	0	111.2	N166 G168 V170 R224 I225	N166-K228 VanDerWaalsContact O-CE 3.28Å; N166-K228 WeakPolarHBondContact O-CE 3.03Å; N166-K228 PolarHBondContact O-NZ 3.29Å; G168-K228 WeakPolarHBondContact O-CD 3.42Å; V170-K228 HydrophobicContact CG2-CB 3.91Å; V170-K228 HydrophobicContact CG2-CD 3.87Å; R224-K228 WeakPolarHBondContact O-CG 3.46Å; I225-K228 PolarHBondContact O-N 2.94Å; I225-K228 VanDerWaalsContact O-N 3.16Å
229	E	87.6	Confident	75.8	Confident	77 Å²	77	68.9 Å²	68.9	36%	0.36	34%	0.336	S	S	.	.			trans	-66.3	134	169.7	-171.1	-178.5	-115.1	0	0	109.4	K155 P169 V170 L264	K155-E229 WeakPolarHBondContact CE-OE2 3.2Å; K155-E229 IonicContact NZ-OE1 2.95Å; K155-E229 PolarHBondContact NZ-OE1 3.3Å; K155-E229 IonicContact NZ-OE2 2.69Å; K155-E229 PolarHBondContact NZ-OE2 3.05Å; P169-E229 CarbonylContact C-O 3.58Å; P169-E229 VanDerWaalsContact CA-O 3.31Å; P169-E229 WeakPolarHBondContact CA-O 3.29Å; P169-E229 HydrophobicContact CB-CB 4.35Å; P169-E229 WeakPolarHBondContact CB-O 3.5Å; V170-E229 PolarHBondContact N-O 3.01Å; E229-L264 HydrophobicContact CG-CD1 3.65Å; E229-L264 WeakPolarHBondContact OE1-CD1 3.33Å
230	I	91.1	Very high	77.8	Confident	7 Å²	7	59.5 Å²	59.5	4%	0.036	30%	0.295	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-107.5	129.8	-177.6	-58.2	175.8	0	0	0	109.2	V170 I172 L210 V232 L256 K261 P263 L264	V170-I230 HydrophobicContact CB-CG1 4.49Å; V170-I230 WeakPolarHBondContact O-CA 3.36Å; I172-I230 HydrophobicContact CD1-CG2 3.54Å; I172-I230 HydrophobicContact CG1-CG2 4.25Å; L210-I230 HydrophobicContact CD2-CD1 4.19Å; I230-V232 HydrophobicContact CG2-CG2 4.2Å; I230-L256 HydrophobicContact CD1-CD2 4.06Å; I230-L256 HydrophobicContact CG2-CD1 4.01Å; I230-K261 HydrophobicContact CD1-CB 4.24Å; I230-K261 HydrophobicContact CD1-CD 4.29Å; I230-K261 HydrophobicContact CD1-CG 4.03Å; I230-P263 HydrophobicContact CG2-CB 4.4Å; I230-P263 WeakPolarHBondContact O-CA 3.25Å; I230-L264 PolarHBondContact O-N 2.82Å
231	I	93.8	Very high	79.5	Confident	0 Å²	0	55.1 Å²	55.1	0%	0	28%	0.276	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-121.9	127.1	-179.1	-56.7	179.2	0	0	0	108	I147 L152 P169 V170 I171 I172 L264	I147-I231 HydrophobicContact CD1-CD1 3.92Å; I147-I231 HydrophobicContact CG2-CG2 3.86Å; L152-I231 HydrophobicContact CD1-CD1 3.49Å; L152-I231 VanDerWaalsContact CD1-CD1 3.49Å; L152-I231 HydrophobicContact CD1-CG2 4.49Å; L152-I231 HydrophobicContact CD2-CG2 4.35Å; P169-I231 HydrophobicContact CB-CD1 3.66Å; P169-I231 HydrophobicContact CB-CG1 4.14Å; P169-I231 HydrophobicContact CG-CD1 3.83Å; V170-I231 PolarHBondContact O-N 3.38Å; I171-I231 CarbonylContact C-O 3.5Å; I171-I231 WeakPolarHBondContact CA-O 3.43Å; I172-I231 PolarHBondContact N-O 2.66Å; I231-L264 CarbonylContact C-O 3.55Å; I231-L264 WeakPolarHBondContact CA-O 3.27Å; I231-L264 HydrophobicContact CG1-CB 4.32Å; I231-L264 HydrophobicContact CG1-CD1 4.41Å
232	V	95.3	Very high	81	Confident	0 Å²	0	61.9 Å²	61.9	0%	0	30%	0.298	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-119.6	137	-178.2	-169.3	0	0	0	0	109.2	I172 C174 I230 L249 V252 L253 L256 P263 L264 V265 L266	I172-V232 HydrophobicContact CB-CG1 4.42Å; I172-V232 HydrophobicContact CB-CG2 4.26Å; I172-V232 HydrophobicContact CD1-CG2 4.36Å; I172-V232 HydrophobicContact CG2-CG1 4.35Å; I172-V232 WeakPolarHBondContact O-CA 3.22Å; C174-V232 HydrophobicContact CB-CG1 4.5Å; I230-V232 HydrophobicContact CG2-CG2 4.2Å; V232-L249 HydrophobicContact CB-CD1 4.33Å; V232-L249 HydrophobicContact CG1-CD1 3.67Å; V232-V252 HydrophobicContact CG1-CB 4.4Å; V232-V252 HydrophobicContact CG1-CG1 3.78Å; V232-V252 HydrophobicContact CG2-CG1 4.25Å; V232-L253 HydrophobicContact CB-CD2 4.23Å; V232-L253 HydrophobicContact CG2-CD2 4.16Å; V232-L256 HydrophobicContact CG2-CD1 3.73Å; V232-P263 HydrophobicContact CG2-CB 3.91Å; V232-L264 PolarHBondContact N-O 2.68Å; V232-V265 WeakPolarHBondContact O-CA 3.48Å; V232-L266 PolarHBondContact O-N 3.15Å
233	Y	95.4	Very high	82.7	Confident	0 Å²	0	58.5 Å²	58.5	0%	0	28%	0.284	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-141.7	154.2	177.3	74	-83	0	0	0	112.5	I171 I172 D173 C174 H184 I185 A188 L266 L270	I171-Y233 HydrophobicContact CG2-CD1 3.86Å; I171-Y233 HydrophobicContact CG2-CE1 3.6Å; I172-Y233 WeakPolarHBondContact O-CD1 3.24Å; I172-Y233 PolarHBondContact O-N 3.36Å; D173-Y233 HydrophobicContact CB-CE1 3.81Å; D173-Y233 HydrophobicContact CB-CE2 4.23Å; D173-Y233 WeakPolarHBondContact OD2-CE2 3.3Å; D173-Y233 PolarHBondContact OD2-OH 3.02Å; C174-Y233 PolarHBondContact N-O 3.27Å; C174-Y233 VanDerWaalsContact N-O 3.12Å; C174-Y233 PolarHBondContact SG-O 3.22Å; H184-Y233 WeakPolarHBondContact CB-OH 3.32Å; I185-Y233 HydrophobicContact CB-CE1 4.25Å; I185-Y233 HydrophobicContact CD1-CD1 4.08Å; I185-Y233 HydrophobicContact CD1-CD2 4.36Å; I185-Y233 HydrophobicContact CD1-CE1 3.92Å; I185-Y233 HydrophobicContact CD1-CE2 4.21Å; I185-Y233 HydrophobicContact CD1-CG 4.29Å; I185-Y233 HydrophobicContact CG1-CE1 4.14Å; I185-Y233 HydrophobicContact CG1-CE2 4.17Å; I185-Y233 PolarHBondContact N-OH 3.09Å; A188-Y233 HydrophobicContact CB-CE1 3.93Å; Y233-L266 HydrophobicContact CG-CD2 4.15Å; Y233-L270 HydrophobicContact CD2-CB 4.09Å; Y233-L270 HydrophobicContact CE2-CB 3.9Å; Y233-L270 HydrophobicContact CE2-CD1 4.15Å
234	D	93.6	Very high	84.2	Confident	18 Å²	18	55 Å²	55	10%	0.096	27%	0.271	C	S	.	.			trans	-119.3	-159	169.3	72	-11.2	0	0	0	110.2	R175 N236 T237 L249 G269 L270	R175-D234 HydrophobicContact CG-CB 4.35Å; D234-N236 PolarHBondContact OD1-N 3.08Å; D234-T237 WeakPolarHBondContact OD1-CB 3.33Å; D234-T237 PolarHBondContact OD1-N 3.35Å; D234-T237 PolarHBondContact OD1-OG1 2.91Å; D234-T237 VanDerWaalsContact OD2-CB 3.23Å; D234-T237 WeakPolarHBondContact OD2-CB 3.45Å; D234-T237 PolarHBondContact OD2-OG1 2.74Å; D234-L249 HydrophobicContact CB-CB 4.41Å; D234-L249 HydrophobicContact CB-CD2 4.37Å; D234-G269 CarbonylContact O-C 3.58Å; D234-G269 WeakPolarHBondContact O-CA 3.47Å; D234-L270 PolarHBondContact O-N 3.27Å
235	E	92.5	Very high	85.4	Confident	54 Å²	54	51.8 Å²	51.8	25%	0.252	27%	0.268	S	S	.	.	S	Bend	trans	-70.3	-48	-176.8	-171.2	54.3	-127.7	0	0	112.4	R175 G269 L270 S271	R175-E235 WeakPolarHBondContact CD-OE2 3.33Å; R175-E235 HydrophobicContact CG-CB 4.42Å; R175-E235 IonicContact CZ-OE2 3.56Å; R175-E235 IonicContact NE-OE2 2.82Å; R175-E235 IonicContact NH1-OE2 3.01Å; R175-E235 PolarHBondContact NH1-OE2 3.49Å; E235-G269 CarbonylContact O-C 3.51Å; E235-L270 PolarHBondContact O-N 3.15Å; E235-L270 VanDerWaalsContact O-N 3.13Å; E235-S271 VanDerWaalsContact O-CB 3.3Å; E235-S271 WeakPolarHBondContact O-CB 3.36Å; E235-S271 PolarHBondContact O-N 3.39Å; E235-S271 PolarHBondContact O-OG 3.21Å; E235-S271 PolarHBondContact OE1-OG 3.27Å
236	N	93.5	Very high	86.2	Confident	98 Å²	98	55.6 Å²	55.6	52%	0.524	29%	0.294	S	S	.	.	S	Bend	trans	-156.3	20.8	-167.1	61.8	12.7	0	0	0	115.9	D234 N238 G268	D234-N236 PolarHBondContact OD1-N 3.08Å; N236-N238 PolarHBondContact O-N 3.48Å; N236-N238 PolarHBondContact O-ND2 3.32Å; N236-G268 WeakPolarHBondContact CA-O 3.45Å
237	T	92.4	Very high	87.2	Confident	17 Å²	17	55.4 Å²	55.4	10%	0.104	29%	0.294	C	S	.	.			trans	-67.5	117.8	-179.9	-75.9	0	0	0	0	111.8	D234 P240 V243 L249 G268	D234-T237 WeakPolarHBondContact OD1-CB 3.33Å; D234-T237 PolarHBondContact OD1-N 3.35Å; D234-T237 PolarHBondContact OD1-OG1 2.91Å; D234-T237 VanDerWaalsContact OD2-CB 3.23Å; D234-T237 WeakPolarHBondContact OD2-CB 3.45Å; D234-T237 PolarHBondContact OD2-OG1 2.74Å; T237-P240 HydrophobicContact CG2-CG 4.33Å; T237-V243 HydrophobicContact CG2-CG2 3.66Å; T237-L249 HydrophobicContact CG2-CD2 3.85Å; T237-G268 WeakPolarHBondContact O-CA 3.21Å; T237-G268 PolarHBondContact O-N 2.93Å
238	N	88.2	Confident	88.3	Confident	97 Å²	97	51.6 Å²	51.6	52%	0.519	27%	0.267	S	S	.	.	S	Bend	trans	-95.8	-25.8	177.3	-78.3	-68	0	0	0	114	N236 G268	N236-N238 PolarHBondContact O-N 3.48Å; N236-N238 PolarHBondContact O-ND2 3.32Å; N238-G268 VanDerWaalsContact OD1-CA 3.29Å; N238-G268 WeakPolarHBondContact OD1-CA 3.46Å; N238-G268 PolarHBondContact OD1-N 3.23Å
239	E	87.5	Confident	89	Confident	84 Å²	84	49.7 Å²	49.7	39%	0.393	26%	0.259	S	S	.	.			trans	-128.4	86.5	-175.9	-166.2	172.8	-172	0	0	110.4	S241 R242	E239-S241 WeakPolarHBondContact CG-OG 3.35Å; E239-S241 PolarHBondContact O-N 2.9Å; E239-S241 VanDerWaalsContact O-N 3.11Å; E239-R242 VanDerWaalsContact CD-CZ 3.46Å; E239-R242 HydrophobicContact CG-CG 4.06Å; E239-R242 PolarHBondContact O-N 3.2Å; E239-R242 VanDerWaalsContact O-N 3.1Å; E239-R242 IonicContact OE1-CZ 3.63Å; E239-R242 IonicContact OE1-NE 3.34Å; E239-R242 PolarHBondContact OE1-NE 3.27Å; E239-R242 IonicContact OE1-NH2 2.99Å; E239-R242 PolarHBondContact OE1-NH2 3.36Å; E239-R242 WeakPolarHBondContact OE2-CD 3.45Å; E239-R242 IonicContact OE2-CZ 3.93Å; E239-R242 IonicContact OE2-NE 2.72Å; E239-R242 PolarHBondContact OE2-NE 3.13Å; E239-R242 IonicContact OE2-NH1 3.81Å; E239-R242 IonicContact OE2-NH2 3.67Å; E239-R242 PolarHBondContact OE2-NH2 2.87Å
240	P	84.3	Confident	89.2	Confident	4 Å²	4	46.8 Å²	46.8	3%	0.026	25%	0.245	C	C	.	.	G	3₁₀ helix	trans	-60.2	-24.8	-174.5	-27.8	37.8	0	0	0	114.3	I144 I146 T237 R242 V243 V265	I144-P240 HydrophobicContact CB-CB 4.06Å; I144-P240 VanDerWaalsContact CD1-C 3.46Å; I144-P240 HydrophobicContact CD1-CB 3.75Å; I144-P240 WeakPolarHBondContact CD1-O 3.48Å; I144-P240 HydrophobicContact CG2-CB 3.64Å; I144-P240 HydrophobicContact CG2-CG 4.36Å; I146-P240 HydrophobicContact CD1-CG 4.13Å; I146-P240 HydrophobicContact CG1-CG 4.12Å; T237-P240 HydrophobicContact CG2-CG 4.33Å; P240-R242 PolarHBondContact O-N 3.2Å; P240-V243 VanDerWaalsContact O-CG2 3.26Å; P240-V243 WeakPolarHBondContact O-CG2 3.49Å; P240-V243 PolarHBondContact O-N 3.47Å; P240-V265 HydrophobicContact CB-CB 4.16Å; P240-V265 HydrophobicContact CB-CG1 4.09Å; P240-V265 HydrophobicContact CB-CG2 4.21Å; P240-V265 HydrophobicContact CG-CB 3.77Å; P240-V265 HydrophobicContact CG-CG1 3.54Å; P240-V265 HydrophobicContact CG-CG2 4.37Å
241	S	83.1	Confident	89.2	Confident	54 Å²	54	46.6 Å²	46.6	38%	0.378	24%	0.244	S	C	.	.	G	3₁₀ helix	trans	-67.2	-15.3	178.3	53.9	0	0	0	0	114.2	Q140 E239	Q140-S241 PolarHBondContact NE2-O 2.64Å; E239-S241 WeakPolarHBondContact CG-OG 3.35Å; E239-S241 PolarHBondContact O-N 2.9Å; E239-S241 VanDerWaalsContact O-N 3.11Å
242	R	84.4	Confident	89.1	Confident	167 Å²	167	46.6 Å²	46.6	63%	0.63	24%	0.244	S	C	*	.	G	3₁₀ helix	trans	-104.3	4.7	178.7	-61.6	-169.4	-170.4	174.5	19.2	113.8	E239 P240 M244	E239-R242 VanDerWaalsContact CD-CZ 3.46Å; E239-R242 HydrophobicContact CG-CG 4.06Å; E239-R242 PolarHBondContact O-N 3.2Å; E239-R242 VanDerWaalsContact O-N 3.1Å; E239-R242 IonicContact OE1-CZ 3.63Å; E239-R242 IonicContact OE1-NE 3.34Å; E239-R242 PolarHBondContact OE1-NE 3.27Å; E239-R242 IonicContact OE1-NH2 2.99Å; E239-R242 PolarHBondContact OE1-NH2 3.36Å; E239-R242 WeakPolarHBondContact OE2-CD 3.45Å; E239-R242 IonicContact OE2-CZ 3.93Å; E239-R242 IonicContact OE2-NE 2.72Å; E239-R242 PolarHBondContact OE2-NE 3.13Å; E239-R242 IonicContact OE2-NH1 3.81Å; E239-R242 IonicContact OE2-NH2 3.67Å; E239-R242 PolarHBondContact OE2-NH2 2.87Å; P240-R242 PolarHBondContact O-N 3.2Å; R242-M244 WeakPolarHBondContact O-CE 3.45Å; R242-M244 PolarHBondContact O-N 3.48Å
243	V	86.8	Confident	88.9	Confident	13 Å²	13	46.7 Å²	46.7	8%	0.079	24%	0.244	C	C	.	.			trans	-69	127.2	-177.9	-178.7	0	0	0	0	109.8	T237 P240 Q247 L249 H250	T237-V243 HydrophobicContact CG2-CG2 3.66Å; P240-V243 VanDerWaalsContact O-CG2 3.26Å; P240-V243 WeakPolarHBondContact O-CG2 3.49Å; P240-V243 PolarHBondContact O-N 3.47Å; V243-Q247 HydrophobicContact CG1-CB 3.84Å; V243-Q247 VanDerWaalsContact CG1-OE1 3.24Å; V243-L249 HydrophobicContact CG1-CB 4.06Å; V243-L249 HydrophobicContact CG1-CD2 4.32Å; V243-L249 HydrophobicContact CG1-CG 4.29Å; V243-L249 HydrophobicContact CG2-CD2 3.87Å; V243-H250 HydrophobicContact CG1-CB 3.83Å; V243-H250 PolarHBondContact O-ND1 2.76Å
244	M	85.6	Confident	88.7	Confident	106 Å²	106	50.2 Å²	50.2	52%	0.522	26%	0.261	S	S	.	.			trans	-75	149.1	-176.4	-67.4	-66.4	108.6	0	0	111.9	R242 S246 Q247 H250	R242-M244 WeakPolarHBondContact O-CE 3.45Å; R242-M244 PolarHBondContact O-N 3.48Å; M244-S246 PolarHBondContact O-N 2.99Å; M244-Q247 HydrophobicContact CB-CG 4.27Å; M244-Q247 WeakPolarHBondContact O-CB 3.38Å; M244-Q247 PolarHBondContact O-N 3.31Å; M244-H250 WeakPolarHBondContact O-CB 3.46Å
245	P	84.9	Confident	88.5	Confident	62 Å²	62	49.4 Å²	49.4	40%	0.403	26%	0.257	S	S	.	.	T	Hydrogen-bonded Turn	trans	-58.1	-20.4	176.5	-26.2	35.2	0	0	0	115.5
246	S	81.3	Confident	88.4	Confident	80 Å²	80	46.8 Å²	46.8	56%	0.559	25%	0.245	S	C	*	.	T	Hydrogen-bonded Turn	trans	-82.1	-9.6	175.4	58.7	0	0	0	0	113.7	R199 M244	R199-S246 PolarHBondContact NH1-O 3.36Å; M244-S246 PolarHBondContact O-N 2.99Å
247	Q	86.6	Confident	88.2	Confident	74 Å²	74	44.6 Å²	44.6	35%	0.346	23%	0.23	S	C	.	.	S	Bend	trans	-86.5	141	-178.8	-70.2	178.5	-60.6	0	0	111.2	V243 M244 L249 H250 I251	V243-Q247 HydrophobicContact CG1-CB 3.84Å; V243-Q247 VanDerWaalsContact CG1-OE1 3.24Å; M244-Q247 HydrophobicContact CB-CG 4.27Å; M244-Q247 WeakPolarHBondContact O-CB 3.38Å; M244-Q247 PolarHBondContact O-N 3.31Å; Q247-L249 PolarHBondContact O-N 3.41Å; Q247-H250 PolarHBondContact O-N 2.93Å; Q247-I251 PolarHBondContact O-N 3.07Å
248	P	89.7	Confident	87.9	Confident	31 Å²	31	49.4 Å²	49.4	20%	0.201	25%	0.246	C	C	.	.	H	α-helix	trans	-48.1	-43.9	176	-32.5	38.6	0	0	0	113.8	C174 C193 H250 I251 V252	C174-P248 HydrophobicContact CB-CB 4.26Å; C174-P248 WeakPolarHBondContact O-CB 3.5Å; C193-P248 HydrophobicContact CB-CB 3.9Å; C193-P248 HydrophobicContact CB-CG 4.39Å; P248-H250 VanDerWaalsContact C-N 3.34Å; P248-H250 PolarHBondContact O-N 3.42Å; P248-I251 PolarHBondContact O-N 3.19Å; P248-I251 VanDerWaalsContact O-N 3.15Å; P248-V252 WeakPolarHBondContact O-CG2 3.37Å; P248-V252 PolarHBondContact O-N 2.99Å
249	L	91.9	Very high	87.8	Confident	1 Å²	1	47.3 Å²	47.3	1%	0.005	23%	0.234	C	C	.	.	H	α-helix	trans	-56.4	-45.5	178.7	-178.4	58.9	0	0	0	112	C174 V232 D234 T237 V243 Q247 I251 L253 V265	C174-L249 VanDerWaalsContact SG-CA 3.56Å; V232-L249 HydrophobicContact CB-CD1 4.33Å; V232-L249 HydrophobicContact CG1-CD1 3.67Å; D234-L249 HydrophobicContact CB-CB 4.41Å; D234-L249 HydrophobicContact CB-CD2 4.37Å; T237-L249 HydrophobicContact CG2-CD2 3.85Å; V243-L249 HydrophobicContact CG1-CB 4.06Å; V243-L249 HydrophobicContact CG1-CD2 4.32Å; V243-L249 HydrophobicContact CG1-CG 4.29Å; V243-L249 HydrophobicContact CG2-CD2 3.87Å; Q247-L249 PolarHBondContact O-N 3.41Å; L249-I251 VanDerWaalsContact C-N 3.35Å; L249-I251 PolarHBondContact O-N 3.27Å; L249-L253 HydrophobicContact CD1-CD1 3.96Å; L249-L253 HydrophobicContact CD1-CG 4.16Å; L249-L253 HydrophobicContact CG-CD1 3.92Å; L249-L253 WeakPolarHBondContact O-CB 3.42Å; L249-L253 WeakPolarHBondContact O-CD1 3.18Å; L249-L253 WeakPolarHBondContact O-CG 3.48Å; L249-L253 PolarHBondContact O-N 3Å; L249-V265 HydrophobicContact CD1-CG1 4.39Å; L249-V265 HydrophobicContact CD2-CG1 4.21Å
250	H	92	Very high	87.8	Confident	16 Å²	16	46.4 Å²	46.4	7%	0.074	25%	0.247	C	C	.	.	H	α-helix	trans	-62.3	-43.7	178.1	-172.6	101.4	0	0	0	111.9	V243 M244 Q247 P248 V252 L253 E254	V243-H250 HydrophobicContact CG1-CB 3.83Å; V243-H250 PolarHBondContact O-ND1 2.76Å; M244-H250 WeakPolarHBondContact O-CB 3.46Å; Q247-H250 PolarHBondContact O-N 2.93Å; P248-H250 VanDerWaalsContact C-N 3.34Å; P248-H250 PolarHBondContact O-N 3.42Å; H250-V252 PolarHBondContact O-N 3.32Å; H250-L253 PolarHBondContact O-N 2.8Å; H250-E254 VanDerWaalsContact O-CB 3.31Å; H250-E254 WeakPolarHBondContact O-CB 3.39Å; H250-E254 PolarHBondContact O-N 3.39Å
251	I	90.8	Very high	87.9	Confident	2 Å²	2	47.8 Å²	47.8	1%	0.01	25%	0.253	C	S	.	.	H	α-helix	trans	-65.3	-43.1	-175.7	-60.6	177.4	0	0	0	110.6	R199 L202 Q203 Q247 P248 L249 S255	R199-I251 HydrophobicContact CG-CD1 3.58Å; L202-I251 HydrophobicContact CB-CG2 4.03Å; Q203-I251 HydrophobicContact CG-CD1 4.34Å; Q203-I251 HydrophobicContact CG-CG1 4.35Å; Q203-I251 HydrophobicContact CG-CG2 3.99Å; Q247-I251 PolarHBondContact O-N 3.07Å; P248-I251 PolarHBondContact O-N 3.19Å; P248-I251 VanDerWaalsContact O-N 3.15Å; L249-I251 VanDerWaalsContact C-N 3.35Å; L249-I251 PolarHBondContact O-N 3.27Å; I251-S255 WeakPolarHBondContact O-CB 3.39Å; I251-S255 PolarHBondContact O-N 2.89Å
252	V	90.9	Very high	88.2	Confident	0 Å²	0	50.6 Å²	50.6	0%	0	26%	0.26	C	S	.	.	H	α-helix	trans	-64.2	-45.6	175.5	174.2	0	0	0	0	110.7	I172 C174 I191 C193 V209 V232 P248 H250 S255 L256	I172-V252 HydrophobicContact CG2-CG1 4.14Å; C174-V252 HydrophobicContact CB-CB 4.47Å; C174-V252 HydrophobicContact CB-CG2 3.84Å; I191-V252 HydrophobicContact CG2-CG2 4.11Å; C193-V252 VanDerWaalsContact SG-CG2 3.57Å; V209-V252 HydrophobicContact CG2-CG1 4.18Å; V232-V252 HydrophobicContact CG1-CB 4.4Å; V232-V252 HydrophobicContact CG1-CG1 3.78Å; V232-V252 HydrophobicContact CG2-CG1 4.25Å; P248-V252 WeakPolarHBondContact O-CG2 3.37Å; P248-V252 PolarHBondContact O-N 2.99Å; H250-V252 PolarHBondContact O-N 3.32Å; V252-S255 PolarHBondContact O-N 3.09Å; V252-L256 HydrophobicContact CG1-CD1 3.91Å; V252-L256 WeakPolarHBondContact O-CG 3.39Å; V252-L256 PolarHBondContact O-N 3.06Å
253	L	91.9	Very high	88.6	Confident	2 Å²	2	42.8 Å²	42.8	1%	0.01	23%	0.231	C	C	.	.	H	α-helix	trans	-63.6	-42.8	178.7	-68.4	171.7	0	0	0	112.5	L141 I144 V232 L249 H250 L256 K257 P263 V265	L141-L253 HydrophobicContact CD2-CB 3.88Å; L141-L253 HydrophobicContact CD2-CD1 4.32Å; I144-L253 HydrophobicContact CD1-CD1 4.43Å; V232-L253 HydrophobicContact CB-CD2 4.23Å; V232-L253 HydrophobicContact CG2-CD2 4.16Å; L249-L253 HydrophobicContact CD1-CD1 3.96Å; L249-L253 HydrophobicContact CD1-CG 4.16Å; L249-L253 HydrophobicContact CG-CD1 3.92Å; L249-L253 WeakPolarHBondContact O-CB 3.42Å; L249-L253 WeakPolarHBondContact O-CD1 3.18Å; L249-L253 WeakPolarHBondContact O-CG 3.48Å; L249-L253 PolarHBondContact O-N 3Å; H250-L253 PolarHBondContact O-N 2.8Å; L253-L256 PolarHBondContact O-N 2.86Å; L253-K257 WeakPolarHBondContact O-CB 3.48Å; L253-K257 WeakPolarHBondContact O-CG 3.47Å; L253-K257 PolarHBondContact O-N 2.97Å; L253-P263 HydrophobicContact CD2-CB 3.91Å; L253-P263 HydrophobicContact CD2-CG 3.52Å; L253-V265 HydrophobicContact CD1-CG2 3.69Å; L253-V265 HydrophobicContact CD2-CG2 3.64Å; L253-V265 HydrophobicContact CG-CG2 4.27Å
254	E	90.6	Very high	88.9	Confident	74 Å²	74	43.3 Å²	43.3	35%	0.346	23%	0.233	S	C	.	.	H	α-helix	trans	-64.9	-43.1	177.8	-169.7	-173.9	-170.8	0	0	111.1	H250 L256 K257 R258	H250-E254 VanDerWaalsContact O-CB 3.31Å; H250-E254 WeakPolarHBondContact O-CB 3.39Å; H250-E254 PolarHBondContact O-N 3.39Å; E254-L256 PolarHBondContact O-N 2.85Å; E254-K257 PolarHBondContact O-N 3.18Å; E254-R258 WeakPolarHBondContact O-CB 3.14Å; E254-R258 PolarHBondContact O-N 3.11Å; E254-R258 IonicContact OE1-NH2 3.34Å; E254-R258 IonicContact OE2-NH2 2.71Å
255	S	90.2	Very high	89.4	Confident	1 Å²	1	38.2 Å²	38.2	1%	0.007	21%	0.208	C	C	.	.	H	α-helix	trans	-59.1	-47.2	175.3	-174.7	0	0	0	0	111.5	V209 I251 V252 R258 E259	V209-S255 PolarHBondContact N-OG 2.82Å; I251-S255 WeakPolarHBondContact O-CB 3.39Å; I251-S255 PolarHBondContact O-N 2.89Å; V252-S255 PolarHBondContact O-N 3.09Å; S255-R258 WeakPolarHBondContact O-CB 3.42Å; S255-R258 PolarHBondContact O-N 3Å; S255-E259 PolarHBondContact O-N 3.3Å
256	L	89.4	Confident	89.9	Confident	0 Å²	0	35.3 Å²	35.3	0%	0	19%	0.189	C	C	.	.	H	α-helix	trans	-65.5	-40.3	179.7	-72.1	168.7	0	0	0	112.1	I172 V209 L210 I230 V232 V252 L253 E254 R258 E259 G260 K261 P263	I172-L256 HydrophobicContact CD1-CD1 4.07Å; V209-L256 HydrophobicContact CB-CD2 3.92Å; V209-L256 HydrophobicContact CB-CG 4.19Å; V209-L256 HydrophobicContact CG1-CD2 3.82Å; V209-L256 HydrophobicContact CG1-CG 4.19Å; V209-L256 HydrophobicContact CG2-CG 4.46Å; L210-L256 HydrophobicContact CD2-CD2 4.24Å; L210-L256 HydrophobicContact CG-CD2 4.41Å; I230-L256 HydrophobicContact CD1-CD2 4.06Å; I230-L256 HydrophobicContact CG2-CD1 4.01Å; V232-L256 HydrophobicContact CG2-CD1 3.73Å; V252-L256 HydrophobicContact CG1-CD1 3.91Å; V252-L256 WeakPolarHBondContact O-CG 3.39Å; V252-L256 PolarHBondContact O-N 3.06Å; L253-L256 PolarHBondContact O-N 2.86Å; E254-L256 PolarHBondContact O-N 2.85Å; L256-R258 VanDerWaalsContact C-N 3.34Å; L256-R258 PolarHBondContact O-N 2.97Å; L256-E259 CarbonylContact O-C 3.53Å; L256-E259 PolarHBondContact O-N 3.39Å; L256-E259 VanDerWaalsContact O-N 3.16Å; L256-G260 PolarHBondContact O-N 3.21Å; L256-K261 HydrophobicContact CB-CB 4.28Å; L256-K261 WeakPolarHBondContact O-CB 3.27Å; L256-K261 PolarHBondContact O-N 2.96Å; L256-P263 HydrophobicContact CB-CG 4.1Å; L256-P263 HydrophobicContact CD1-CB 3.98Å; L256-P263 HydrophobicContact CD1-CG 4.19Å
257	K	89.2	Confident	90.6	Very high	52 Å²	52	34.7 Å²	34.7	23%	0.226	18%	0.176	C	C	.	.	H	α-helix	trans	-64.6	-37.1	175.9	-77.2	-177	175.1	-170.1	0	112.5	L141 A142 L253 E254 E259 G260	L141-K257 HydrophobicContact CD1-CD 4.39Å; L141-K257 HydrophobicContact CD2-CD 3.99Å; L141-K257 HydrophobicContact CG-CD 4.03Å; A142-K257 PolarHBondContact O-NZ 3.17Å; L253-K257 WeakPolarHBondContact O-CB 3.48Å; L253-K257 WeakPolarHBondContact O-CG 3.47Å; L253-K257 PolarHBondContact O-N 2.97Å; E254-K257 PolarHBondContact O-N 3.18Å; K257-E259 PolarHBondContact O-N 3.35Å; K257-G260 PolarHBondContact O-N 3.03Å
258	R	87.8	Confident	90.8	Very high	117 Å²	117	31.2 Å²	31.2	44%	0.442	16%	0.16	S	C	.	.	H	α-helix	trans	-61.2	-30	174.7	-165.1	-178.7	-56.7	126.7	1.2	112.1	L202 Q203 E254 S255 L256 G260	L202-R258 PolarHBondContact O-NH1 3.45Å; Q203-R258 PolarHBondContact O-NH2 2.5Å; E254-R258 WeakPolarHBondContact O-CB 3.14Å; E254-R258 PolarHBondContact O-N 3.11Å; E254-R258 IonicContact OE1-NH2 3.34Å; E254-R258 IonicContact OE2-NH2 2.71Å; S255-R258 WeakPolarHBondContact O-CB 3.42Å; S255-R258 PolarHBondContact O-N 3Å; L256-R258 VanDerWaalsContact C-N 3.34Å; L256-R258 PolarHBondContact O-N 2.97Å; R258-G260 VanDerWaalsContact C-N 3.26Å; R258-G260 PolarHBondContact O-N 3.43Å
259	E	85.7	Confident	91	Very high	54 Å²	54	29.8 Å²	29.8	25%	0.252	15%	0.151	S	C	.	.	T	Hydrogen-bonded Turn	trans	-86.6	11.1	174.8	-63	-175	102.5	0	0	113.5	T208 L210 S255 L256 K257 K261	T208-E259 WeakPolarHBondContact CB-OE1 3.34Å; T208-E259 VanDerWaalsContact CB-OE2 3.29Å; T208-E259 WeakPolarHBondContact CB-OE2 3.24Å; T208-E259 HydrophobicContact CG2-CG 4.24Å; T208-E259 WeakPolarHBondContact CG2-OE1 3.36Å; T208-E259 VanDerWaalsContact OG1-CD 3.28Å; T208-E259 PolarHBondContact OG1-OE1 3.42Å; T208-E259 PolarHBondContact OG1-OE2 3.28Å; L210-E259 HydrophobicContact CD1-CB 4.19Å; L210-E259 WeakPolarHBondContact CG-OE2 3.37Å; S255-E259 PolarHBondContact O-N 3.3Å; L256-E259 CarbonylContact O-C 3.53Å; L256-E259 PolarHBondContact O-N 3.39Å; L256-E259 VanDerWaalsContact O-N 3.16Å; K257-E259 PolarHBondContact O-N 3.35Å; E259-K261 VanDerWaalsContact C-N 3.27Å; E259-K261 PolarHBondContact O-N 3.42Å
260	G	85.9	Confident	91.2	Very high	65 Å²	65	29.8 Å²	29.8	67%	0.67	15%	0.151	S	C	*	.	T	Hydrogen-bonded Turn	trans	71	20.2	179.4	0	0	0	0	0	114	L256 K257 R258	L256-G260 PolarHBondContact O-N 3.21Å; K257-G260 PolarHBondContact O-N 3.03Å; R258-G260 VanDerWaalsContact C-N 3.26Å; R258-G260 PolarHBondContact O-N 3.43Å
261	K	87.9	Confident	91.2	Very high	33 Å²	33	31.8 Å²	31.8	14%	0.143	17%	0.167	C	C	.	.			trans	-92.4	149.8	174.3	-58.2	-59.2	-176	-173.3	0	111.4	L210 F226 I230 L256 E259 P263	L210-K261 HydrophobicContact CD1-CG 4.21Å; F226-K261 VanDerWaalsContact CA-NZ 3.32Å; F226-K261 PolarHBondContact O-NZ 2.98Å; I230-K261 HydrophobicContact CD1-CB 4.24Å; I230-K261 HydrophobicContact CD1-CD 4.29Å; I230-K261 HydrophobicContact CD1-CG 4.03Å; L256-K261 HydrophobicContact CB-CB 4.28Å; L256-K261 WeakPolarHBondContact O-CB 3.27Å; L256-K261 PolarHBondContact O-N 2.96Å; E259-K261 VanDerWaalsContact C-N 3.27Å; E259-K261 PolarHBondContact O-N 3.42Å; K261-P263 VanDerWaalsContact C-CD 3.43Å; K261-P263 WeakPolarHBondContact O-CD 3.11Å
262	E	89.1	Confident	91.3	Very high	112 Å²	112	33.5 Å²	33.5	52%	0.523	18%	0.179	S	C	.	.			trans	-113.7	76	179.4	-72.7	-73.4	122.9	0	0	109.6	K145	K145-E262 IonicContact NZ-OE2 3.24Å; K145-E262 PolarHBondContact NZ-OE2 3.23Å
263	P	91.9	Very high	91.5	Very high	4 Å²	4	33.5 Å²	33.5	3%	0.026	18%	0.179	C	C	.	.	P	Polyproline II helix	trans	-68.7	144	-177.5	28.4	-35.3	0	0	0	112.2	I230 V232 L253 L256 K261	I230-P263 HydrophobicContact CG2-CB 4.4Å; I230-P263 WeakPolarHBondContact O-CA 3.25Å; V232-P263 HydrophobicContact CG2-CB 3.91Å; L253-P263 HydrophobicContact CD2-CB 3.91Å; L253-P263 HydrophobicContact CD2-CG 3.52Å; L256-P263 HydrophobicContact CB-CG 4.1Å; L256-P263 HydrophobicContact CD1-CB 3.98Å; L256-P263 HydrophobicContact CD1-CG 4.19Å; K261-P263 VanDerWaalsContact C-CD 3.43Å; K261-P263 WeakPolarHBondContact O-CD 3.11Å
264	L	94.4	Very high	91.5	Very high	23 Å²	23	35.9 Å²	35.9	12%	0.12	19%	0.189	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-90	136.4	167.9	-69.4	160.9	0	0	0	109.6	K145 I147 E229 I230 I231 V232	K145-L264 HydrophobicContact CB-CD2 3.48Å; K145-L264 VanDerWaalsContact CB-CD2 3.48Å; K145-L264 WeakPolarHBondContact O-CA 3.37Å; I147-L264 HydrophobicContact CB-CB 4.31Å; I147-L264 HydrophobicContact CG2-CB 4.14Å; E229-L264 HydrophobicContact CG-CD1 3.65Å; E229-L264 WeakPolarHBondContact OE1-CD1 3.33Å; I230-L264 PolarHBondContact O-N 2.82Å; I231-L264 CarbonylContact C-O 3.55Å; I231-L264 WeakPolarHBondContact CA-O 3.27Å; I231-L264 HydrophobicContact CG1-CB 4.32Å; I231-L264 HydrophobicContact CG1-CD1 4.41Å; V232-L264 PolarHBondContact N-O 2.68Å
265	V	95.7	Very high	91.4	Very high	0 Å²	0	39.6 Å²	39.6	0%	0	21%	0.206	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-98.2	130.1	172.9	-179.6	0	0	0	0	110.4	I144 K145 I146 I147 V232 P240 L249 L253 K267	I144-V265 HydrophobicContact CG2-CB 4.07Å; I144-V265 HydrophobicContact CG2-CG2 3.46Å; I144-V265 VanDerWaalsContact CG2-CG2 3.46Å; K145-V265 PolarHBondContact O-N 3.4Å; I146-V265 CarbonylContact C-O 3.46Å; I146-V265 WeakPolarHBondContact CA-O 3.37Å; I147-V265 PolarHBondContact N-O 3.12Å; V232-V265 WeakPolarHBondContact O-CA 3.48Å; P240-V265 HydrophobicContact CB-CB 4.16Å; P240-V265 HydrophobicContact CB-CG1 4.09Å; P240-V265 HydrophobicContact CB-CG2 4.21Å; P240-V265 HydrophobicContact CG-CB 3.77Å; P240-V265 HydrophobicContact CG-CG1 3.54Å; P240-V265 HydrophobicContact CG-CG2 4.37Å; L249-V265 HydrophobicContact CD1-CG1 4.39Å; L249-V265 HydrophobicContact CD2-CG1 4.21Å; L253-V265 HydrophobicContact CD1-CG2 3.69Å; L253-V265 HydrophobicContact CD2-CG2 3.64Å; L253-V265 HydrophobicContact CG-CG2 4.27Å; V265-K267 PolarHBondContact O-N 2.94Å
266	L	96	Very high	91.3	Very high	0 Å²	0	44.4 Å²	44.4	0%	0	23%	0.232	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-71.4	117.1	174.5	-178.8	59.4	0	0	0	110.4	I147 P149 L152 I185 V232 Y233 G268 G269 F273	I147-L266 HydrophobicContact CG2-CB 4.35Å; I147-L266 HydrophobicContact CG2-CD1 4.2Å; I147-L266 WeakPolarHBondContact O-CA 3.5Å; P149-L266 HydrophobicContact CG-CD1 4.23Å; L152-L266 HydrophobicContact CB-CD1 4.32Å; L152-L266 HydrophobicContact CD2-CD1 3.81Å; L152-L266 HydrophobicContact CD2-CD2 3.8Å; L152-L266 HydrophobicContact CD2-CG 4.35Å; I185-L266 HydrophobicContact CD1-CD2 3.52Å; V232-L266 PolarHBondContact O-N 3.15Å; Y233-L266 HydrophobicContact CG-CD2 4.15Å; L266-G268 PolarHBondContact O-N 3.46Å; L266-G269 PolarHBondContact O-N 3.19Å; L266-F273 HydrophobicContact CD1-CD2 4.4Å; L266-F273 HydrophobicContact CD2-CB 4.05Å; L266-F273 HydrophobicContact CD2-CD2 4.23Å; L266-F273 HydrophobicContact CD2-CG 4.34Å
267	K	94.4	Very high	91.4	Very high	67 Å²	67	45.8 Å²	45.8	29%	0.291	24%	0.238	S	C	.	.	T	Hydrogen-bonded Turn	trans	-66	127.2	178.9	-160.7	-179.6	-176.7	177.2	0	110.9	I146 I147 Y148 V265 G269	I146-K267 HydrophobicContact CG2-CB 3.6Å; I146-K267 HydrophobicContact CG2-CD 4.32Å; I146-K267 HydrophobicContact CG2-CG 4.16Å; I147-K267 PolarHBondContact O-N 3.45Å; Y148-K267 HydrophobicContact CD1-CB 4.42Å; Y148-K267 HydrophobicContact CD1-CD 3.86Å; Y148-K267 HydrophobicContact CE1-CD 3.33Å; V265-K267 PolarHBondContact O-N 2.94Å; K267-G269 PolarHBondContact O-N 3.4Å
268	G	91.9	Very high	91.3	Very high	2 Å²	2	47.9 Å²	47.9	2%	0.021	25%	0.249	C	C	.	.	T	Hydrogen-bonded Turn	trans	76	11.8	178.4	0	0	0	0	0	113.8	N236 T237 N238 L266 S272	N236-G268 WeakPolarHBondContact CA-O 3.45Å; T237-G268 WeakPolarHBondContact O-CA 3.21Å; T237-G268 PolarHBondContact O-N 2.93Å; N238-G268 VanDerWaalsContact OD1-CA 3.29Å; N238-G268 WeakPolarHBondContact OD1-CA 3.46Å; N238-G268 PolarHBondContact OD1-N 3.23Å; L266-G268 PolarHBondContact O-N 3.46Å; G268-S272 VanDerWaalsContact O-CB 3.25Å; G268-S272 WeakPolarHBondContact O-CB 3.4Å; G268-S272 PolarHBondContact O-N 2.91Å
269	G	94.5	Very high	91.2	Very high	0 Å²	0	48 Å²	48	0%	0	26%	0.259	C	S	.	.	H	α-helix	trans	58.2	-154.9	173.5	0	0	0	0	0	114.6	D234 E235 L266 K267 S271 F273	D234-G269 CarbonylContact O-C 3.58Å; D234-G269 WeakPolarHBondContact O-CA 3.47Å; E235-G269 CarbonylContact O-C 3.51Å; L266-G269 PolarHBondContact O-N 3.19Å; K267-G269 PolarHBondContact O-N 3.4Å; G269-S271 VanDerWaalsContact C-N 3.34Å; G269-F273 PolarHBondContact O-N 3.26Å
270	L	94.3	Very high	91.4	Very high	2 Å²	2	46.4 Å²	46.4	1%	0.01	25%	0.251	C	S	.	.	H	α-helix	trans	-63.2	-41.1	175.2	-175.5	68.4	0	0	0	111.7	R175 S183 I185 Y233 D234 E235 S272 F273 K274	R175-L270 VanDerWaalsContact CZ-CD2 3.43Å; S183-L270 WeakPolarHBondContact O-CD2 3.3Å; I185-L270 HydrophobicContact CD1-CD1 4.42Å; I185-L270 HydrophobicContact CG1-CD1 3.6Å; Y233-L270 HydrophobicContact CD2-CB 4.09Å; Y233-L270 HydrophobicContact CE2-CB 3.9Å; Y233-L270 HydrophobicContact CE2-CD1 4.15Å; D234-L270 PolarHBondContact O-N 3.27Å; E235-L270 PolarHBondContact O-N 3.15Å; E235-L270 VanDerWaalsContact O-N 3.13Å; L270-S272 VanDerWaalsContact C-N 3.34Å; L270-S272 PolarHBondContact O-N 2.99Å; L270-F273 PolarHBondContact O-N 3.16Å; L270-K274 HydrophobicContact CD1-CD 4.33Å; L270-K274 HydrophobicContact CD1-CG 4Å; L270-K274 HydrophobicContact CD2-CD 4.06Å; L270-K274 HydrophobicContact CG-CD 3.9Å; L270-K274 HydrophobicContact CG-CG 3.96Å; L270-K274 WeakPolarHBondContact O-CB 3.17Å; L270-K274 PolarHBondContact O-N 2.84Å
271	S	92.6	Very high	91.5	Very high	57 Å²	57	43.7 Å²	43.7	40%	0.399	22%	0.222	S	C	.	.	H	α-helix	trans	-54.1	-48.8	-177.4	-79.3	0	0	0	0	111.9	E235 G269 F273	E235-S271 VanDerWaalsContact O-CB 3.3Å; E235-S271 WeakPolarHBondContact O-CB 3.36Å; E235-S271 PolarHBondContact O-N 3.39Å; E235-S271 PolarHBondContact O-OG 3.21Å; E235-S271 PolarHBondContact OE1-OG 3.27Å; G269-S271 VanDerWaalsContact C-N 3.34Å; S271-F273 VanDerWaalsContact C-N 3.35Å
272	S	93.6	Very high	91.1	Very high	38 Å²	38	45.4 Å²	45.4	27%	0.266	23%	0.233	S	C	.	.	H	α-helix	trans	-71.8	-29.2	177.8	-175.1	0	0	0	0	113.1	G268 L270	G268-S272 VanDerWaalsContact O-CB 3.25Å; G268-S272 WeakPolarHBondContact O-CB 3.4Å; G268-S272 PolarHBondContact O-N 2.91Å; L270-S272 VanDerWaalsContact C-N 3.34Å; L270-S272 PolarHBondContact O-N 2.99Å
273	F	94.3	Very high	90.4	Very high	0 Å²	0	42.3 Å²	42.3	0%	0	22%	0.22	C	C	.	.	H	α-helix	trans	-70.3	-47.2	178.3	-173.5	-93.2	0	0	0	111.7	P149 L152 A153 M156 I185 L266 G269 L270 S271 Q275 N276 H277 L280	P149-F273 HydrophobicContact CB-CB 4.47Å; P149-F273 HydrophobicContact CB-CD2 3.92Å; L152-F273 HydrophobicContact CB-CE2 4Å; L152-F273 HydrophobicContact CD2-CD2 3.99Å; L152-F273 HydrophobicContact CD2-CE2 3.75Å; L152-F273 HydrophobicContact CD2-CZ 4.48Å; L152-F273 HydrophobicContact CG-CD2 4.41Å; L152-F273 HydrophobicContact CG-CE2 3.75Å; L152-F273 HydrophobicContact CG-CZ 4.43Å; A153-F273 HydrophobicContact CB-CE2 4.24Å; A153-F273 HydrophobicContact CB-CZ 4.41Å; M156-F273 HydrophobicContact SD-CZ 3.97Å; I185-F273 HydrophobicContact CD1-CB 4.37Å; I185-F273 HydrophobicContact CD1-CD1 3.84Å; I185-F273 HydrophobicContact CD1-CD2 4.2Å; I185-F273 HydrophobicContact CD1-CE1 4.13Å; I185-F273 HydrophobicContact CD1-CG 3.87Å; I185-F273 HydrophobicContact CD1-CZ 4.46Å; I185-F273 HydrophobicContact CG1-CD1 3.78Å; I185-F273 HydrophobicContact CG1-CE1 3.97Å; I185-F273 HydrophobicContact CG1-CG 4.32Å; I185-F273 HydrophobicContact CG2-CE1 4.05Å; I185-F273 HydrophobicContact CG2-CZ 4.25Å; L266-F273 HydrophobicContact CD1-CD2 4.4Å; L266-F273 HydrophobicContact CD2-CB 4.05Å; L266-F273 HydrophobicContact CD2-CD2 4.23Å; L266-F273 HydrophobicContact CD2-CG 4.34Å; G269-F273 PolarHBondContact O-N 3.26Å; L270-F273 PolarHBondContact O-N 3.16Å; S271-F273 VanDerWaalsContact C-N 3.35Å; F273-Q275 VanDerWaalsContact C-N 3.25Å; F273-Q275 PolarHBondContact O-N 3.03Å; F273-N276 PolarHBondContact O-N 3.01Å; F273-H277 HydrophobicContact CD1-CB 4.06Å; F273-H277 HydrophobicContact CE1-CB 3.7Å; F273-H277 HydrophobicContact CE2-CB 4.19Å; F273-H277 HydrophobicContact CG-CB 4.47Å; F273-H277 HydrophobicContact CZ-CB 3.76Å; F273-H277 WeakPolarHBondContact O-CB 3.44Å; F273-H277 PolarHBondContact O-N 2.92Å; F273-L280 HydrophobicContact CE1-CB 3.95Å; F273-L280 HydrophobicContact CZ-CB 4.05Å; F273-L280 HydrophobicContact CZ-CD1 4.24Å
274	K	91.4	Very high	88.9	Confident	52 Å²	52	44.4 Å²	44.4	23%	0.226	24%	0.235	C	C	.	.	H	α-helix	trans	-56.9	-35.7	178.9	-84.5	-172.4	155.6	-151.9	0	114.1	S183 L270 N276 H277 E278 C281 N283	S183-K274 WeakPolarHBondContact OG-CE 3.44Å; S183-K274 PolarHBondContact OG-NZ 3.27Å; L270-K274 HydrophobicContact CD1-CD 4.33Å; L270-K274 HydrophobicContact CD1-CG 4Å; L270-K274 HydrophobicContact CD2-CD 4.06Å; L270-K274 HydrophobicContact CG-CD 3.9Å; L270-K274 HydrophobicContact CG-CG 3.96Å; L270-K274 WeakPolarHBondContact O-CB 3.17Å; L270-K274 PolarHBondContact O-N 2.84Å; K274-N276 PolarHBondContact O-N 2.97Å; K274-N276 VanDerWaalsContact O-N 3.09Å; K274-H277 PolarHBondContact O-N 3.44Å; K274-E278 PolarHBondContact O-N 3.35Å; K274-C281 HydrophobicContact CG-CB 4.38Å; K274-C281 VanDerWaalsContact CG-SG 3.56Å; K274-N283 PolarHBondContact NZ-OD1 3.47Å
275	Q	90.2	Very high	86.4	Confident	152 Å²	152	48.2 Å²	48.2	71%	0.71	26%	0.255	S	S	*	.	H	α-helix	trans	-54.2	-34.3	-176.5	-171	175.8	25.8	0	0	113.7	F273	F273-Q275 VanDerWaalsContact C-N 3.25Å; F273-Q275 PolarHBondContact O-N 3.03Å
276	N	87.9	Confident	83.8	Confident	102 Å²	102	54.5 Å²	54.5	55%	0.545	28%	0.284	S	S	.	.	H	α-helix	trans	-122.9	-6.7	-177.3	-61.1	-55.3	0	0	0	113.6	F273 K274	F273-N276 PolarHBondContact O-N 3.01Å; K274-N276 PolarHBondContact O-N 2.97Å; K274-N276 VanDerWaalsContact O-N 3.09Å
277	H	90.4	Very high	81	Confident	29 Å²	29	60.4 Å²	60.4	13%	0.134	32%	0.315	C	S	.	.	H	α-helix	trans	-138.5	38.4	-173.5	-56	-74.6	0	0	0	111.9	N150 A153 F273 K274 N279 L280	N150-H277 PolarHBondContact OD1-NE2 3.44Å; A153-H277 HydrophobicContact CB-CB 4.5Å; A153-H277 VanDerWaalsContact CB-CE1 3.4Å; A153-H277 WeakPolarHBondContact CB-CE1 3.38Å; A153-H277 WeakPolarHBondContact CB-ND1 3.35Å; F273-H277 HydrophobicContact CD1-CB 4.06Å; F273-H277 HydrophobicContact CE1-CB 3.7Å; F273-H277 HydrophobicContact CE2-CB 4.19Å; F273-H277 HydrophobicContact CG-CB 4.47Å; F273-H277 HydrophobicContact CZ-CB 3.76Å; F273-H277 WeakPolarHBondContact O-CB 3.44Å; F273-H277 PolarHBondContact O-N 2.92Å; K274-H277 PolarHBondContact O-N 3.44Å; H277-N279 PolarHBondContact O-N 3.25Å; H277-L280 HydrophobicContact CB-CB 4.48Å; H277-L280 HydrophobicContact CB-CD1 4.34Å; H277-L280 PolarHBondContact O-N 3.22Å
278	E	87.4	Confident	78	Confident	96 Å²	96	65.5 Å²	65.5	45%	0.449	34%	0.34	S	S	.	.	G	3₁₀ helix	trans	-57.6	-34.8	179.3	-171.5	171	-164.5	0	0	112.3	K274 L280 C281 N283	K274-E278 PolarHBondContact O-N 3.35Å; E278-L280 PolarHBondContact O-N 3.49Å; E278-L280 VanDerWaalsContact O-N 3.13Å; E278-C281 WeakPolarHBondContact O-CB 3.11Å; E278-C281 PolarHBondContact O-N 3.37Å; E278-N283 PolarHBondContact OE1-ND2 2.71Å
279	N	86.6	Confident	75	Confident	120 Å²	120	74.3 Å²	74.3	64%	0.642	38%	0.38	S	S	*	.	G	3₁₀ helix	trans	-65.8	-12.2	177.3	69.5	-71.7	0	0	0	114.5	Q186 H277	Q186-N279 PolarHBondContact NE2-O 3.18Å; H277-N279 PolarHBondContact O-N 3.25Å
280	L	89.4	Confident	71.7	Confident	20 Å²	20	79.4 Å²	79.4	11%	0.105	42%	0.415	C	S	.	.	G	3₁₀ helix	trans	-103.3	11.4	174.3	-61.8	179.1	0	0	0	112	A153 M156 T157 Q186 F273 H277 E278	A153-L280 HydrophobicContact CB-CD1 3.66Å; M156-L280 HydrophobicContact CE-CB 4.32Å; T157-L280 HydrophobicContact CG2-CD1 4.32Å; T157-L280 HydrophobicContact CG2-CD2 4.36Å; Q186-L280 WeakPolarHBondContact CB-O 3.39Å; Q186-L280 WeakPolarHBondContact CG-O 3.48Å; Q186-L280 PolarHBondContact N-O 2.94Å; F273-L280 HydrophobicContact CE1-CB 3.95Å; F273-L280 HydrophobicContact CZ-CB 4.05Å; F273-L280 HydrophobicContact CZ-CD1 4.24Å; H277-L280 HydrophobicContact CB-CB 4.48Å; H277-L280 HydrophobicContact CB-CD1 4.34Å; H277-L280 PolarHBondContact O-N 3.22Å; E278-L280 PolarHBondContact O-N 3.49Å; E278-L280 VanDerWaalsContact O-N 3.13Å
281	C	88.4	Confident	68.9	Low	9 Å²	9	85.4 Å²	85.4	6%	0.061	45%	0.454	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-110.7	140.7	173.6	-58.6	0	0	0	0	109.5	H184 K274 E278	H184-C281 CarbonylContact O-C 3.59Å; H184-C281 VanDerWaalsContact O-CA 3.25Å; H184-C281 WeakPolarHBondContact O-CA 3.48Å; K274-C281 HydrophobicContact CG-CB 4.38Å; K274-C281 VanDerWaalsContact CG-SG 3.56Å; E278-C281 WeakPolarHBondContact O-CB 3.11Å; E278-C281 PolarHBondContact O-N 3.37Å
282	D	79.6	Confident	66	Low	69 Å²	69	92.1 Å²	92.1	37%	0.369	48%	0.479	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-82.9	124.4	166	-69.4	-32.7	0	0	0	108	S183 H184 Q186	S183-D282 CarbonylContact C-O 3.52Å; S183-D282 WeakPolarHBondContact CA-O 3.4Å; S183-D282 VanDerWaalsContact CB-O 3.25Å; S183-D282 WeakPolarHBondContact CB-O 3.47Å; S183-D282 PolarHBondContact OG-O 3.1Å; H184-D282 PolarHBondContact N-O 3Å; H184-D282 VanDerWaalsContact N-O 3.1Å; H184-D282 IonicContact NE2-OD2 3.57Å; H184-D282 PolarHBondContact O-N 3.38Å; Q186-D282 WeakPolarHBondContact CG-OD1 3.24Å; Q186-D282 PolarHBondContact NE2-OD1 2.94Å
283	N	74.3	Confident	63.1	Low	46 Å²	46	94.3 Å²	94.3	25%	0.246	51%	0.508	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-111.9	115.1	175.1	-75.8	-31.2	0	0	0	107.6	S183 K274 E278 L285 Q286	S183-N283 VanDerWaalsContact CB-OD1 3.22Å; S183-N283 WeakPolarHBondContact CB-OD1 3.25Å; S183-N283 PolarHBondContact OG-OD1 3.34Å; K274-N283 PolarHBondContact NZ-OD1 3.47Å; E278-N283 PolarHBondContact OE1-ND2 2.71Å; N283-L285 PolarHBondContact O-N 3.04Å; N283-Q286 PolarHBondContact ND2-OE1 2.7Å
284	S	58.8	Low	60	Low	48 Å²	48	98.3 Å²	98.3	34%	0.336	55%	0.549	S	S	.	.	T	Hydrogen-bonded Turn	trans	-84.5	5.8	-179.7	-139.3	0	0	0	0	112.8	N181 K182 K438	N181-S284 WeakPolarHBondContact O-CB 3.49Å; K182-S284 PolarHBondContact O-N 3.38Å; K182-S284 VanDerWaalsContact O-N 3.12Å; S284-K438 PolarHBondContact OG-NZ 2.86Å
285	L	43.7	Very low	57.1	Low	104 Å²	104	100 Å²	100	55%	0.545	58%	0.581	S	S	.	*	T	Hydrogen-bonded Turn	trans	-134.4	14.1	-169	-71.1	177	0	0	0	116	K182 N283 L287	K182-L285 HydrophobicContact CG-CD1 4.27Å; N283-L285 PolarHBondContact O-N 3.04Å; L285-L287 VanDerWaalsContact C-N 3.27Å; L285-L287 PolarHBondContact O-N 3.48Å
286	Q	39.3	Very low	54.1	Low	132 Å²	132	96.7 Å²	96.7	62%	0.617	59%	0.588	S	S	*	*			trans	-82.1	77.6	176.3	-131.4	154.8	7.4	0	0	110	N283 Q288	N283-Q286 PolarHBondContact ND2-OE1 2.7Å; Q286-Q288 PolarHBondContact O-N 2.9Å
287	L	37	Very low	51.3	Low	124 Å²	124	96.1 Å²	96.1	65%	0.649	61%	0.606	S	S	*	*			trans	-66.5	112.8	150.8	-77.1	161.6	0	0	0	105.7	L285 E289 I316	L285-L287 VanDerWaalsContact C-N 3.27Å; L285-L287 PolarHBondContact O-N 3.48Å; L287-E289 PolarHBondContact O-N 3.48Å; L287-E289 VanDerWaalsContact O-N 3.14Å; L287-I316 HydrophobicContact CD2-CD1 3.88Å; L287-I316 HydrophobicContact CD2-CG2 4.44Å; L287-I316 HydrophobicContact CG-CD1 4.11Å
288	Q	31.9	Very low	48.4	Very low	174 Å²	174	98.7 Å²	98.7	81%	0.813	64%	0.641	S	S	*	*			trans	-68.2	108.9	177.7	-170.7	164.5	-1	0	0	108.2	Q286 C290	Q286-Q288 PolarHBondContact O-N 2.9Å; Q288-C290 PolarHBondContact O-N 3.49Å
289	E	28.9	Very low	45.8	Very low	186 Å²	186	98.7 Å²	98.7	87%	0.869	66%	0.657	S	S	*	*			trans	-62	104.2	165	-73.5	179.3	158.8	0	0	107.9	L287 P291	L287-E289 PolarHBondContact O-N 3.48Å; L287-E289 VanDerWaalsContact O-N 3.14Å; E289-P291 WeakPolarHBondContact O-CD 3.1Å
290	C	26.5	Very low	43.2	Very low	108 Å²	108	98.8 Å²	98.8	73%	0.73	67%	0.667	S	S	*	*	P	Polyproline II helix	trans	-68.4	124.2	167.8	-72.1	0	0	0	0	109	Q288 E292	Q288-C290 PolarHBondContact O-N 3.49Å; C290-E292 PolarHBondContact O-N 3.36Å
291	P	34.7	Very low	40.4	Very low	128 Å²	128	102.6 Å²	102.6	83%	0.831	70%	0.701	S	S	*	*	P	Polyproline II helix	trans	-73.2	116.5	167.7	-8	24.5	0	0	0	108.9	E289	E289-P291 WeakPolarHBondContact O-CD 3.1Å
292	E	32.4	Very low	38	Very low	197 Å²	197	108.7 Å²	108.7	92%	0.921	74%	0.738	S	S	*	*	P	Polyproline II helix	trans	-68.9	134	165	-68.9	-171	146.6	0	0	110.8	C290	C290-E292 PolarHBondContact O-N 3.36Å
293	G	32.3	Very low	36.3	Very low	85 Å²	85	110.7 Å²	110.7	88%	0.876	76%	0.755	S	S	*	*			trans	114.8	114.5	141.6	0	0	0	0	0	117.8
294	G	29.2	Very low	34.9	Very low	83 Å²	83	113.9 Å²	113.9	86%	0.856	78%	0.778	S	S	*	*			trans	148.2	105.9	158.3	0	0	0	0	0	113.3
295	G	29.5	Very low	34	Very low	88 Å²	88	118.2 Å²	118.2	91%	0.907	80%	0.803	S	S	*	*			trans	-93.8	-172.5	-168.2	0	0	0	0	0	116.7
296	G	28.8	Very low	33.3	Very low	83 Å²	83	121.2 Å²	121.2	86%	0.856	82%	0.818	S	S	*	*			trans	138.1	114.1	173.7	0	0	0	0	0	111.8
297	G	28.5	Very low	33.6	Very low	89 Å²	89	120.5 Å²	120.5	92%	0.918	83%	0.825	S	S	*	*			trans	-75.2	172	-173.5	0	0	0	0	0	115.7
298	G	29.8	Very low	33.3	Very low	84 Å²	84	123.1 Å²	123.1	87%	0.866	83%	0.834	S	S	*	*			trans	157.1	127.6	171.1	0	0	0	0	0	112.2
299	A	33.2	Very low	33.5	Very low	96 Å²	96	120.7 Å²	120.7	79%	0.793	84%	0.837	S	S	*	*			trans	-76.2	167.5	-168.5	0	0	0	0	0	116.1
300	S	31.5	Very low	33.6	Very low	122 Å²	122	118.3 Å²	118.3	85%	0.853	83%	0.828	S	S	*	*			trans	74.6	112.2	156.8	-72.8	0	0	0	0	119.3
301	A	30.8	Very low	33.8	Very low	99 Å²	99	119.1 Å²	119.1	82%	0.818	83%	0.832	S	S	*	*				162	125.2	98	0	0	0	0	0	111.5
302	V	38.3	Very low	33.5	Very low	138 Å²	138	118.9 Å²	118.9	84%	0.836	83%	0.829	S	S	*	*			trans	-82.2	137.8	161.5	174.8	0	0	0	0	106.7
303	P	42.5	Very low	33.8	Very low	110 Å²	110	115 Å²	115	71%	0.714	82%	0.819	S	S	*	*				-161.2	-162.7	82.5	40.8	-17.2	0	0	0	115.4
304	P	45.3	Very low	34.3	Very low	113 Å²	113	114.7 Å²	114.7	73%	0.734	80%	0.801	S	S	*	*				-118.9	167.9	-52.5	30	-12.5	0	0	0	112.9
305	T	39.3	Very low	35.5	Very low	139 Å²	139	114.3 Å²	114.3	85%	0.853	78%	0.779	S	S	*	*			trans	-46.3	135.3	169.7	29.5	0	0	0	0	116.4
306	L	30.4	Very low	36.9	Very low	167 Å²	167	112.2 Å²	112.2	87%	0.874	75%	0.747	S	S	*	*			trans	-137.2	135.7	148.5	-94.6	163.3	0	0	0	109.2
307	P	45.4	Very low	37.9	Very low	117 Å²	117	115.1 Å²	115.1	76%	0.76	74%	0.738	S	S	*	*			trans	-94.4	109.3	-173.7	33.8	-26.8	0	0	0	110.6
308	Q	29.9	Very low	39.4	Very low	179 Å²	179	116.6 Å²	116.6	84%	0.836	73%	0.725	S	S	*	*			trans	-140.4	105.4	161	-72.2	-168.3	-22.9	0	0	109.7	I310	Q308-I310 PolarHBondContact O-N 3.05Å
309	S	36.9	Very low	41.6	Very low	124 Å²	124	113.3 Å²	113.3	87%	0.867	69%	0.69	S	S	*	*			trans	-52.1	98.3	166.4	49.7	0	0	0	0	110.5
310	I	30.5	Very low	44.2	Very low	135 Å²	135	116 Å²	116	69%	0.692	69%	0.686	S	S	*	*			trans	-76.3	130.5	158.4	-57.3	166.6	0	0	0	105.3	Q308 T312	Q308-I310 PolarHBondContact O-N 3.05Å; I310-T312 PolarHBondContact O-N 2.97Å
311	P	30.4	Very low	47.3	Very low	125 Å²	125	110.8 Å²	110.8	81%	0.812	65%	0.649	S	S	*	*			trans	-68.1	93.1	168.7	-6.1	21.7	0	0	0	106.8	T313	P311-T313 PolarHBondContact O-N 3.35Å
312	T	28.8	Very low	50.4	Low	124 Å²	124	106.8 Å²	106.8	76%	0.761	61%	0.614	S	S	*	*			trans	-59.9	127.9	171.2	11	0	0	0	0	107.7	I310	I310-T312 PolarHBondContact O-N 2.97Å
313	T	37.6	Very low	53.2	Low	116 Å²	116	103.6 Å²	103.6	71%	0.712	60%	0.596	S	S	*	*			trans	-44	137.9	163.8	44.8	0	0	0	0	109.2	P311 D315	P311-T313 PolarHBondContact O-N 3.35Å; T313-D315 PolarHBondContact O-N 2.89Å
314	P	43.1	Very low	55.7	Low	77 Å²	77	98.3 Å²	98.3	50%	0.5	56%	0.562	S	S	.	*			trans	-58.5	107.6	-178.9	21.7	-29.2	0	0	0	108.1	I316 P442 I443	P314-I316 PolarHBondContact O-N 3.05Å; P314-P442 HydrophobicContact CG-CB 3.94Å; P314-I443 HydrophobicContact CB-CG2 4Å; P314-I443 HydrophobicContact CG-CG2 4.1Å; P314-I443 WeakPolarHBondContact O-CG2 3.43Å
315	D	55.9	Low	58	Low	76 Å²	76	93.2 Å²	93.2	41%	0.406	53%	0.528	S	S	.	.			trans	-64.6	122.4	-174.6	-178.4	-4.1	0	0	0	108.2	T313 E317 N318 A319	T313-D315 PolarHBondContact O-N 2.89Å; D315-E317 PolarHBondContact O-N 3.38Å; D315-E317 VanDerWaalsContact O-N 3.15Å; D315-E317 PolarHBondContact OD1-N 3.45Å; D315-E317 VanDerWaalsContact OD1-N 3.16Å; D315-N318 HydrophobicContact CB-CB 4.11Å; D315-N318 CarbonylContact O-C 3.52Å; D315-N318 PolarHBondContact O-N 2.85Å; D315-N318 PolarHBondContact OD2-ND2 3.26Å; D315-A319 PolarHBondContact O-N 3.4Å; D315-A319 VanDerWaalsContact O-N 3.09Å
316	I	57.1	Low	60.6	Low	44 Å²	44	92.5 Å²	92.5	23%	0.226	53%	0.526	C	S	.	.	T	Hydrogen-bonded Turn	trans	-56	-32.4	-176.9	-65.4	169.9	0	0	0	110	L287 P314 A409 V411 I443	L287-I316 HydrophobicContact CD2-CD1 3.88Å; L287-I316 HydrophobicContact CD2-CG2 4.44Å; L287-I316 HydrophobicContact CG-CD1 4.11Å; P314-I316 PolarHBondContact O-N 3.05Å; I316-A409 HydrophobicContact CG2-CB 4.13Å; I316-V411 HydrophobicContact CG2-CG2 4.12Å; I316-I443 HydrophobicContact CG1-CB 4.45Å; I316-I443 HydrophobicContact CG1-CG2 4.34Å; I316-I443 HydrophobicContact CG2-CD1 4.34Å
317	E	51.3	Low	63.6	Low	143 Å²	143	85.4 Å²	85.4	67%	0.668	49%	0.488	S	S	*	.	T	Hydrogen-bonded Turn	trans	-76.1	-29.2	180	-60.6	-168.6	164.3	0	0	112.6	D315	D315-E317 PolarHBondContact O-N 3.38Å; D315-E317 VanDerWaalsContact O-N 3.15Å; D315-E317 PolarHBondContact OD1-N 3.45Å; D315-E317 VanDerWaalsContact OD1-N 3.16Å
318	N	60.1	Low	66.2	Low	120 Å²	120	79.8 Å²	79.8	64%	0.642	45%	0.452	S	S	*	.	T	Hydrogen-bonded Turn	trans	-103.8	9.5	-176.9	-67.7	-55	0	0	0	114	D315 E320	D315-N318 HydrophobicContact CB-CB 4.11Å; D315-N318 CarbonylContact O-C 3.52Å; D315-N318 PolarHBondContact O-N 2.85Å; D315-N318 PolarHBondContact OD2-ND2 3.26Å; N318-E320 PolarHBondContact O-N 2.96Å
319	A	75.1	Confident	69.4	Low	16 Å²	16	72 Å²	72	13%	0.132	42%	0.416	C	S	.	.			trans	-71.4	104.7	-177	0	0	0	0	0	112.2	D315 N332 R441 I443	D315-A319 PolarHBondContact O-N 3.4Å; D315-A319 VanDerWaalsContact O-N 3.09Å; A319-N332 PolarHBondContact O-ND2 3.39Å; A319-R441 PolarHBondContact O-NH1 3.06Å; A319-R441 PolarHBondContact O-NH2 2.93Å; A319-I443 HydrophobicContact CB-CD1 3.39Å; A319-I443 HydrophobicContact CB-CG1 4.04Å; A319-I443 HydrophobicContact CB-CG2 4.43Å
320	E	88.6	Confident	72.4	Confident	152 Å²	152	66.1 Å²	66.1	71%	0.71	37%	0.374	S	S	*	.			trans	-57.1	149.4	-180	-57.7	-176.3	-180	0	0	113.7	N318 T322 R441	N318-E320 PolarHBondContact O-N 2.96Å; E320-T322 PolarHBondContact O-N 2.97Å; E320-T322 VanDerWaalsContact O-N 3.15Å; E320-T322 PolarHBondContact O-OG1 2.81Å; E320-T322 VanDerWaalsContact O-OG1 3.06Å; E320-R441 PolarHBondContact O-NH1 2.8Å
321	L	95.4	Very high	75.5	Confident	13 Å²	13	59.7 Å²	59.7	7%	0.068	34%	0.341	C	S	.	.			trans	-40.5	119.2	166.3	-174.1	54.6	0	0	0	112.8	F329 D335 K341 L345 I347 L404	L321-F329 HydrophobicContact CD1-CB 3.67Å; L321-F329 HydrophobicContact CD2-CB 4.29Å; L321-F329 HydrophobicContact CD2-CD1 4.43Å; L321-F329 HydrophobicContact CG-CB 4.01Å; L321-F329 HydrophobicContact CG-CD1 4.33Å; L321-D335 WeakPolarHBondContact CA-OD2 3.19Å; L321-D335 HydrophobicContact CB-CB 4.19Å; L321-D335 VanDerWaalsContact CB-OD1 3.29Å; L321-D335 WeakPolarHBondContact CB-OD1 3.36Å; L321-D335 HydrophobicContact CD1-CB 4.17Å; L321-D335 PolarHBondContact N-OD1 3.44Å; L321-D335 PolarHBondContact N-OD2 3.28Å; L321-K341 HydrophobicContact CB-CD 4.48Å; L321-L345 HydrophobicContact CD2-CD1 3.41Å; L321-L345 VanDerWaalsContact CD2-CD1 3.41Å; L321-L345 HydrophobicContact CG-CD1 4.39Å; L321-I347 HydrophobicContact CD2-CD1 4.15Å; L321-L404 HydrophobicContact CD1-CD1 3.38Å
322	T	96.8	Very high	78.5	Confident	14 Å²	14	54.1 Å²	54.1	9%	0.086	30%	0.304	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-103.6	121.7	-171.7	-47.6	0	0	0	0	111.9	E320 I324 F329 L330 K440 R441	E320-T322 PolarHBondContact O-N 2.97Å; E320-T322 VanDerWaalsContact O-N 3.15Å; E320-T322 PolarHBondContact O-OG1 2.81Å; E320-T322 VanDerWaalsContact O-OG1 3.06Å; T322-I324 HydrophobicContact CG2-CD1 4.04Å; T322-I324 PolarHBondContact O-N 2.67Å; T322-F329 CarbonylContact O-C 3.56Å; T322-F329 WeakPolarHBondContact O-CA 3.07Å; T322-L330 PolarHBondContact N-O 3.49Å; T322-L330 PolarHBondContact O-N 3.35Å; T322-K440 HydrophobicContact CG2-CB 3.81Å; T322-K440 VanDerWaalsContact CG2-O 3.28Å; T322-K440 WeakPolarHBondContact CG2-O 3.44Å; T322-R441 HydrophobicContact CG2-CB 3.92Å; T322-R441 PolarHBondContact OG1-NH1 2.83Å
323	P	96.3	Very high	81.7	Confident	71 Å²	71	50.1 Å²	50.1	46%	0.461	28%	0.277	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-76	106.8	174.1	29.5	-32.9	0	0	0	111.7	F329 K440	P323-F329 HydrophobicContact CB-CD1 3.92Å; P323-F329 HydrophobicContact CB-CE1 3.86Å; P323-K440 WeakPolarHBondContact O-CD 3.22Å; P323-K440 PolarHBondContact O-NZ 2.72Å
324	I	96.2	Very high	84.4	Confident	0 Å²	0	49.8 Å²	49.8	0%	0	27%	0.267	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-82.5	-46.7	178.1	-54.8	-55.4	0	0	0	110.7	T322 L328 L330 V418 L422 F436 V437 K440	T322-I324 HydrophobicContact CG2-CD1 4.04Å; T322-I324 PolarHBondContact O-N 2.67Å; I324-L328 WeakPolarHBondContact CA-O 3.32Å; I324-L328 PolarHBondContact N-O 2.91Å; I324-L330 HydrophobicContact CD1-CB 4.07Å; I324-L330 HydrophobicContact CD1-CD2 4.36Å; I324-L330 HydrophobicContact CG1-CB 3.71Å; I324-V418 HydrophobicContact CB-CG1 4.33Å; I324-V418 HydrophobicContact CG1-CG1 4.1Å; I324-V418 HydrophobicContact CG2-CG1 3.73Å; I324-L422 HydrophobicContact CG2-CD1 4.18Å; I324-F436 HydrophobicContact CG2-CD1 4.4Å; I324-F436 HydrophobicContact CG2-CE1 3.85Å; I324-V437 HydrophobicContact CD1-CG1 3.9Å; I324-V437 HydrophobicContact CG2-CG2 4.37Å; I324-K440 HydrophobicContact CD1-CB 4.2Å; I324-K440 HydrophobicContact CD1-CD 4.33Å; I324-K440 PolarHBondContact O-NZ 3Å
325	L	93.6	Very high	86.9	Confident	5 Å²	5	46.5 Å²	46.5	3%	0.026	25%	0.246	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-128.4	167.2	169.7	-60.5	172.8	0	0	0	108.4	F327 L328 Y421 L422 L474 V477	L325-F327 HydrophobicContact CB-CD1 4.19Å; L325-F327 HydrophobicContact CB-CE1 4.01Å; L325-F327 HydrophobicContact CD1-CE1 3.91Å; L325-F327 HydrophobicContact CD1-CZ 3.91Å; L325-F327 PolarHBondContact O-N 3.1Å; L325-L328 HydrophobicContact CB-CB 3.93Å; L325-L328 HydrophobicContact CD1-CB 4.37Å; L325-L328 HydrophobicContact CD1-CD2 4.27Å; L325-L328 HydrophobicContact CG-CB 4.38Å; L325-L328 PolarHBondContact N-O 3.45Å; L325-L328 VanDerWaalsContact N-O 3.09Å; L325-L328 PolarHBondContact O-N 3.4Å; L325-Y421 HydrophobicContact CD1-CE1 3.83Å; L325-L422 HydrophobicContact CD1-CD2 4.13Å; L325-L422 HydrophobicContact CD2-CD2 4.3Å; L325-L422 HydrophobicContact CG-CD2 4.37Å; L325-L474 HydrophobicContact CD1-CD2 4.08Å; L325-V477 HydrophobicContact CD2-CG1 4.45Å; L325-V477 HydrophobicContact CD2-CG2 3.67Å
326	P	92.3	Very high	88.9	Confident	125 Å²	125	43 Å²	43	81%	0.812	23%	0.227	S	C	*	.	T	Hydrogen-bonded Turn	trans	-52.8	-26	178.7	-29.1	36.9	0	0	0	114.6
327	F	95.4	Very high	90.8	Very high	17 Å²	17	44.9 Å²	44.9	8%	0.075	24%	0.235	C	C	.	.	T	Hydrogen-bonded Turn	trans	-115.7	-2.1	179.2	69.8	-84.1	0	0	0	113.8	L325 I393 H397 G402 L403 Y421 L474	L325-F327 HydrophobicContact CB-CD1 4.19Å; L325-F327 HydrophobicContact CB-CE1 4.01Å; L325-F327 HydrophobicContact CD1-CE1 3.91Å; L325-F327 HydrophobicContact CD1-CZ 3.91Å; L325-F327 PolarHBondContact O-N 3.1Å; F327-I393 HydrophobicContact CE2-CG2 3.74Å; F327-H397 AromaticContact CD1-CE1 3.72Å; F327-H397 AromaticContact CD1-ND1 3.26Å; F327-H397 VanDerWaalsContact CD1-ND1 3.26Å; F327-H397 WeakPolarHBondContact CD1-ND1 3.42Å; F327-H397 HydrophobicContact CD2-CB 3.74Å; F327-H397 AromaticContact CD2-ND1 3.84Å; F327-H397 AromaticContact CE1-CE1 3.72Å; F327-H397 AromaticContact CE1-CG 3.87Å; F327-H397 AromaticContact CE1-ND1 3.44Å; F327-H397 WeakPolarHBondContact CE1-ND1 3.32Å; F327-H397 HydrophobicContact CE2-CB 3.57Å; F327-H397 AromaticContact CE2-CG 3.84Å; F327-H397 AromaticContact CE2-ND1 3.99Å; F327-H397 HydrophobicContact CG-CB 4.28Å; F327-H397 AromaticContact CG-ND1 3.47Å; F327-H397 WeakPolarHBondContact CG-ND1 3.43Å; F327-H397 HydrophobicContact CZ-CB 3.99Å; F327-H397 AromaticContact CZ-CG 3.75Å; F327-H397 AromaticContact CZ-ND1 3.8Å; F327-G402 CarbonylContact O-C 3.48Å; F327-G402 WeakPolarHBondContact O-CA 3.4Å; F327-L403 PolarHBondContact O-N 2.98Å; F327-Y421 WeakPolarHBondContact CZ-OH 3.38Å; F327-L474 HydrophobicContact CE1-CD2 3.79Å; F327-L474 HydrophobicContact CZ-CD2 4.18Å
328	L	98.1	Very high	92.9	Very high	0 Å²	0	41.1 Å²	41.1	0%	0	22%	0.219	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-121.8	118.8	-174.7	-177.9	62.8	0	0	0	110.7	I324 L325 I393 L403 I405 V418 Y421	I324-L328 WeakPolarHBondContact CA-O 3.32Å; I324-L328 PolarHBondContact N-O 2.91Å; L325-L328 HydrophobicContact CB-CB 3.93Å; L325-L328 HydrophobicContact CD1-CB 4.37Å; L325-L328 HydrophobicContact CD1-CD2 4.27Å; L325-L328 HydrophobicContact CG-CB 4.38Å; L325-L328 PolarHBondContact N-O 3.45Å; L325-L328 VanDerWaalsContact N-O 3.09Å; L325-L328 PolarHBondContact O-N 3.4Å; L328-I393 HydrophobicContact CD1-CD1 4.41Å; L328-I393 HydrophobicContact CD1-CG1 4.32Å; L328-I393 HydrophobicContact CD1-CG2 4.32Å; L328-L403 HydrophobicContact CD1-CB 4.41Å; L328-L403 HydrophobicContact CD1-CD2 3.62Å; L328-I405 HydrophobicContact CD1-CG2 4.1Å; L328-V418 HydrophobicContact CD2-CG1 4.37Å; L328-Y421 HydrophobicContact CD2-CD1 3.82Å; L328-Y421 HydrophobicContact CD2-CE1 4.03Å
329	F	98.6	Very high	94.7	Very high	16 Å²	16	37 Å²	37	7%	0.07	20%	0.197	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-118.9	134.2	-176.5	-55.3	-96.1	0	0	0	111.2	L321 T322 P323 L345 I347 L403 I405	L321-F329 HydrophobicContact CD1-CB 3.67Å; L321-F329 HydrophobicContact CD2-CB 4.29Å; L321-F329 HydrophobicContact CD2-CD1 4.43Å; L321-F329 HydrophobicContact CG-CB 4.01Å; L321-F329 HydrophobicContact CG-CD1 4.33Å; T322-F329 CarbonylContact O-C 3.56Å; T322-F329 WeakPolarHBondContact O-CA 3.07Å; P323-F329 HydrophobicContact CB-CD1 3.92Å; P323-F329 HydrophobicContact CB-CE1 3.86Å; F329-L345 HydrophobicContact CD1-CD1 4.11Å; F329-L345 HydrophobicContact CE1-CB 4.38Å; F329-L345 HydrophobicContact CE1-CD1 3.93Å; F329-L345 HydrophobicContact CE1-CD2 4Å; F329-L345 HydrophobicContact CE1-CG 4.33Å; F329-L345 HydrophobicContact CE2-CB 4.49Å; F329-L345 HydrophobicContact CZ-CB 4.09Å; F329-L345 HydrophobicContact CZ-CD1 4.45Å; F329-L345 HydrophobicContact CZ-CD2 4.25Å; F329-I347 HydrophobicContact CD2-CD1 4.15Å; F329-I347 HydrophobicContact CD2-CG1 4.09Å; F329-I347 HydrophobicContact CE2-CG1 4.28Å; F329-I347 HydrophobicContact CG-CD1 4.44Å; F329-L403 PolarHBondContact N-O 3.38Å; F329-I405 WeakPolarHBondContact O-CG2 3.06Å; F329-I405 PolarHBondContact O-N 2.9Å
330	L	98.6	Very high	95.7	Very high	0 Å²	0	43.7 Å²	43.7	0%	0	23%	0.226	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-108.3	120.8	177.7	173.9	60.2	0	0	0	109.9	T322 I324 I405 S414 A415 V418 V437 I444	T322-L330 PolarHBondContact N-O 3.49Å; T322-L330 PolarHBondContact O-N 3.35Å; I324-L330 HydrophobicContact CD1-CB 4.07Å; I324-L330 HydrophobicContact CD1-CD2 4.36Å; I324-L330 HydrophobicContact CG1-CB 3.71Å; L330-I405 WeakPolarHBondContact CA-O 3.25Å; L330-I405 HydrophobicContact CD1-CG2 4.39Å; L330-S414 VanDerWaalsContact CD1-OG 3.25Å; L330-S414 WeakPolarHBondContact CD1-OG 3.42Å; L330-A415 HydrophobicContact CD2-CB 4.15Å; L330-V418 HydrophobicContact CD1-CG2 4.31Å; L330-V437 HydrophobicContact CD2-CG1 3.75Å; L330-I444 HydrophobicContact CD2-CG2 3.88Å
331	G	96.6	Very high	96.1	Very high	0 Å²	0	38 Å²	38	0%	0	20%	0.199	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-139.4	-177.9	-175	0	0	0	0	0	115.3	D335 I405 H406 G410	G331-D335 VanDerWaalsContact CA-OD2 3.22Å; G331-D335 WeakPolarHBondContact CA-OD2 3.25Å; G331-I405 PolarHBondContact N-O 3.1Å; G331-H406 WeakPolarHBondContact O-CA 3.31Å; G331-H406 WeakPolarHBondContact O-CB 3.49Å; G331-G410 WeakPolarHBondContact O-CA 3.41Å
332	N	93.8	Very high	96.2	Very high	7 Å²	7	37.4 Å²	37.4	4%	0.037	20%	0.196	C	C	.	.			trans	-103.8	-173.9	173.7	65.5	24.7	0	0	0	111.4	A319 H334 D335 A336 Q408	A319-N332 PolarHBondContact O-ND2 3.39Å; N332-H334 VanDerWaalsContact C-N 3.32Å; N332-H334 WeakPolarHBondContact OD1-CA 3.27Å; N332-H334 WeakPolarHBondContact OD1-CB 3.44Å; N332-H334 PolarHBondContact OD1-N 3.03Å; N332-D335 PolarHBondContact N-OD2 3Å; N332-D335 PolarHBondContact O-N 3.23Å; N332-D335 PolarHBondContact OD1-N 2.88Å; N332-D335 PolarHBondContact OD1-OD2 3Å; N332-A336 PolarHBondContact O-N 2.99Å; N332-Q408 CarbonylContact C-O 3.31Å; N332-Q408 VanDerWaalsContact CA-O 3.26Å; N332-Q408 WeakPolarHBondContact CA-O 3.13Å; N332-Q408 VanDerWaalsContact CB-O 3.23Å; N332-Q408 WeakPolarHBondContact CB-O 3.41Å
333	E	94.9	Very high	96.1	Very high	40 Å²	40	41.9 Å²	41.9	19%	0.187	22%	0.216	C	C	.	.	H	α-helix	trans	-67	-31	178.5	69.9	-179.3	121.2	0	0	113.4	A336 Q337 L357 Q408	E333-A336 PolarHBondContact O-N 2.65Å; E333-Q337 WeakPolarHBondContact O-CG 3.35Å; E333-Q337 PolarHBondContact O-N 2.8Å; E333-Q337 VanDerWaalsContact O-N 3.16Å; E333-L357 HydrophobicContact CB-CD1 3.73Å; E333-L357 WeakPolarHBondContact OE2-CD2 3.27Å; E333-Q408 PolarHBondContact N-O 3.03Å; E333-Q408 VanDerWaalsContact OE1-CG 3.3Å; E333-Q408 WeakPolarHBondContact OE1-CG 3.42Å; E333-Q408 PolarHBondContact OE1-NE2 2.8Å
334	H	94.2	Very high	96.2	Very high	110 Å²	110	47.8 Å²	47.8	51%	0.509	23%	0.229	S	C	.	.	H	α-helix	trans	-67.8	-41.9	176.4	-58.5	-64.8	0	0	0	111.2	N332 A336 Q337 D338	N332-H334 VanDerWaalsContact C-N 3.32Å; N332-H334 WeakPolarHBondContact OD1-CA 3.27Å; N332-H334 WeakPolarHBondContact OD1-CB 3.44Å; N332-H334 PolarHBondContact OD1-N 3.03Å; H334-A336 PolarHBondContact O-N 2.92Å; H334-Q337 WeakPolarHBondContact O-CB 3.26Å; H334-Q337 PolarHBondContact O-N 3.33Å; H334-D338 PolarHBondContact O-N 2.78Å
335	D	96.4	Very high	96.2	Very high	8 Å²	8	50.5 Å²	50.5	4%	0.043	24%	0.243	C	C	.	.	H	α-helix	trans	-61.3	-30.7	174.4	-63.5	-55.3	0	0	0	112	L321 G331 N332 Q337 K341	L321-D335 WeakPolarHBondContact CA-OD2 3.19Å; L321-D335 HydrophobicContact CB-CB 4.19Å; L321-D335 VanDerWaalsContact CB-OD1 3.29Å; L321-D335 WeakPolarHBondContact CB-OD1 3.36Å; L321-D335 HydrophobicContact CD1-CB 4.17Å; L321-D335 PolarHBondContact N-OD1 3.44Å; L321-D335 PolarHBondContact N-OD2 3.28Å; G331-D335 VanDerWaalsContact CA-OD2 3.22Å; G331-D335 WeakPolarHBondContact CA-OD2 3.25Å; N332-D335 PolarHBondContact N-OD2 3Å; N332-D335 PolarHBondContact O-N 3.23Å; N332-D335 PolarHBondContact OD1-N 2.88Å; N332-D335 PolarHBondContact OD1-OD2 3Å; D335-Q337 VanDerWaalsContact C-N 3.34Å; D335-K341 IonicContact OD1-NZ 2.64Å; D335-K341 PolarHBondContact OD1-NZ 2.9Å
336	A	97.2	Very high	96.3	Very high	3 Å²	3	53.9 Å²	53.9	3%	0.025	26%	0.261	C	S	.	.	H	α-helix	trans	-77	-20	175.4	0	0	0	0	0	113.4	N332 E333 H334 Y360 L404	N332-A336 PolarHBondContact O-N 2.99Å; E333-A336 PolarHBondContact O-N 2.65Å; H334-A336 PolarHBondContact O-N 2.92Å; A336-Y360 HydrophobicContact CB-CD2 3.96Å; A336-Y360 HydrophobicContact CB-CE2 4.48Å; A336-Y360 WeakPolarHBondContact O-CB 3.35Å; A336-L404 HydrophobicContact CB-CD2 4Å
337	Q	96.7	Very high	96.6	Very high	82 Å²	82	48.3 Å²	48.3	38%	0.383	22%	0.224	S	C	.	.	H	α-helix	trans	-86.9	-23.6	173.6	-69.1	173.7	33.6	0	0	112.2	E333 H334 D335 L339 Y360 H361	E333-Q337 WeakPolarHBondContact O-CG 3.35Å; E333-Q337 PolarHBondContact O-N 2.8Å; E333-Q337 VanDerWaalsContact O-N 3.16Å; H334-Q337 WeakPolarHBondContact O-CB 3.26Å; H334-Q337 PolarHBondContact O-N 3.33Å; D335-Q337 VanDerWaalsContact C-N 3.34Å; Q337-L339 PolarHBondContact O-N 3.41Å; Q337-Y360 HydrophobicContact CG-CD1 3.56Å; Q337-Y360 HydrophobicContact CG-CD2 3.85Å; Q337-Y360 HydrophobicContact CG-CE1 3.54Å; Q337-Y360 HydrophobicContact CG-CE2 3.86Å; Q337-Y360 HydrophobicContact CG-CG 3.7Å; Q337-Y360 VanDerWaalsContact NE2-CZ 3.26Å; Q337-Y360 PolarHBondContact NE2-OH 3.31Å; Q337-Y360 VanDerWaalsContact NE2-OH 3.12Å; Q337-H361 PolarHBondContact O-CE1 2.89Å; Q337-H361 PolarHBondContact O-NE2 3.16Å
338	D	96.9	Very high	96.7	Very high	64 Å²	64	48 Å²	48	34%	0.342	23%	0.225	S	C	.	.			trans	-77.3	84.4	-178.2	-170.8	-17.1	0	0	0	112.3	H334 E340 K341 M342	H334-D338 PolarHBondContact O-N 2.78Å; D338-E340 VanDerWaalsContact C-N 3.34Å; D338-E340 PolarHBondContact O-N 3.09Å; D338-E340 PolarHBondContact OD1-N 2.74Å; D338-K341 HydrophobicContact CB-CB 4.06Å; D338-K341 PolarHBondContact O-N 3.13Å; D338-K341 VanDerWaalsContact OD1-CB 3.26Å; D338-K341 WeakPolarHBondContact OD1-CB 3.49Å; D338-K341 PolarHBondContact OD1-N 3.49Å; D338-K341 WeakPolarHBondContact OD2-CB 3.29Å; D338-K341 WeakPolarHBondContact OD2-CD 3.42Å; D338-M342 VanDerWaalsContact O-CG 3.25Å; D338-M342 WeakPolarHBondContact O-CG 3.38Å; D338-M342 PolarHBondContact O-N 3.4Å
339	L	96.9	Very high	96.8	Very high	33 Å²	33	48.6 Å²	48.6	17%	0.173	23%	0.228	C	C	.	.	H	α-helix	trans	-58.4	-42.9	-179.2	177	57.3	0	0	0	113	Q337 M342 Q343 K364 I366 F367	Q337-L339 PolarHBondContact O-N 3.41Å; L339-M342 PolarHBondContact O-N 3.35Å; L339-Q343 HydrophobicContact CD1-CG 4.09Å; L339-Q343 WeakPolarHBondContact O-CG 3.33Å; L339-Q343 PolarHBondContact O-N 3.37Å; L339-K364 HydrophobicContact CD2-CD 4.05Å; L339-K364 VanDerWaalsContact CD2-NZ 3.29Å; L339-I366 HydrophobicContact CD1-CD1 3.21Å; L339-F367 HydrophobicContact CD1-CE2 3.78Å; L339-F367 HydrophobicContact CD1-CZ 3.75Å
340	E	96.8	Very high	96.8	Very high	158 Å²	158	48 Å²	48	74%	0.738	23%	0.225	S	C	*	.	H	α-helix	trans	-66.5	-44.4	-176	-67.3	-176	-176.5	0	0	110.8	D338 Q343 R344	D338-E340 VanDerWaalsContact C-N 3.34Å; D338-E340 PolarHBondContact O-N 3.09Å; D338-E340 PolarHBondContact OD1-N 2.74Å; E340-Q343 PolarHBondContact O-N 2.88Å; E340-R344 WeakPolarHBondContact O-CB 3.39Å; E340-R344 PolarHBondContact O-N 3.18Å
341	K	95.9	Very high	96.8	Very high	31 Å²	31	48 Å²	48	14%	0.135	23%	0.225	C	C	.	.	H	α-helix	trans	-64.1	-41.4	176.4	-172.9	178.8	-174.6	-173.6	0	111.5	L321 D335 D338 R344 L345	L321-K341 HydrophobicContact CB-CD 4.48Å; D335-K341 IonicContact OD1-NZ 2.64Å; D335-K341 PolarHBondContact OD1-NZ 2.9Å; D338-K341 HydrophobicContact CB-CB 4.06Å; D338-K341 PolarHBondContact O-N 3.13Å; D338-K341 VanDerWaalsContact OD1-CB 3.26Å; D338-K341 WeakPolarHBondContact OD1-CB 3.49Å; D338-K341 PolarHBondContact OD1-N 3.49Å; D338-K341 WeakPolarHBondContact OD2-CB 3.29Å; D338-K341 WeakPolarHBondContact OD2-CD 3.42Å; K341-R344 PolarHBondContact O-N 3.28Å; K341-L345 HydrophobicContact CG-CD1 4.23Å; K341-L345 WeakPolarHBondContact O-CG 3.33Å; K341-L345 PolarHBondContact O-N 2.88Å; K341-L345 VanDerWaalsContact O-N 3.1Å
342	M	97.8	Very high	96.9	Very high	2 Å²	2	48 Å²	48	1%	0.01	23%	0.225	C	C	.	.	H	α-helix	trans	-60.6	-46.5	176	-71.6	174.5	71.4	0	0	111.9	D338 L339 L345 N346 I347 V350 F367 L404	D338-M342 VanDerWaalsContact O-CG 3.25Å; D338-M342 WeakPolarHBondContact O-CG 3.38Å; D338-M342 PolarHBondContact O-N 3.4Å; L339-M342 PolarHBondContact O-N 3.35Å; M342-L345 PolarHBondContact O-N 3.02Å; M342-N346 PolarHBondContact O-N 3.42Å; M342-I347 HydrophobicContact CB-CB 4.31Å; M342-I347 HydrophobicContact CB-CD1 4.32Å; M342-I347 HydrophobicContact CE-CG2 4Å; M342-I347 HydrophobicContact CG-CD1 4.21Å; M342-I347 WeakPolarHBondContact O-CB 3.46Å; M342-I347 PolarHBondContact O-N 2.91Å; M342-V350 HydrophobicContact CE-CG2 3.38Å; M342-F367 HydrophobicContact CB-CE1 4.17Å; M342-F367 HydrophobicContact CB-CZ 3.71Å; M342-F367 HydrophobicContact CE-CD1 4.29Å; M342-F367 HydrophobicContact CE-CD2 3.82Å; M342-F367 HydrophobicContact CE-CE1 4.03Å; M342-F367 HydrophobicContact CE-CE2 3.51Å; M342-F367 HydrophobicContact CE-CG 4.2Å; M342-F367 HydrophobicContact CE-CZ 3.63Å; M342-F367 HydrophobicContact SD-CE2 4.14Å; M342-F367 HydrophobicContact SD-CZ 4.21Å; M342-L404 HydrophobicContact CE-CD2 3.96Å; M342-L404 HydrophobicContact CG-CD2 4.37Å; M342-L404 HydrophobicContact SD-CD2 4.09Å
343	Q	96.1	Very high	97.1	Very high	108 Å²	108	47.6 Å²	47.6	51%	0.505	22%	0.223	S	C	.	.	H	α-helix	trans	-64.9	-42.4	177.5	-72.8	-179.3	-34.7	0	0	112.3	L339 E340 L345 N346 F367	L339-Q343 HydrophobicContact CD1-CG 4.09Å; L339-Q343 WeakPolarHBondContact O-CG 3.33Å; L339-Q343 PolarHBondContact O-N 3.37Å; E340-Q343 PolarHBondContact O-N 2.88Å; Q343-L345 PolarHBondContact O-N 3.48Å; Q343-N346 PolarHBondContact O-N 3.49Å; Q343-F367 HydrophobicContact CG-CZ 4.43Å
344	R	97.2	Very high	97	Very high	195 Å²	195	45.7 Å²	45.7	74%	0.736	21%	0.214	S	C	*	.	H	α-helix	trans	-59.9	-34.4	177.6	-176.7	175.7	64.2	-166.3	-2.2	112.6	E340 K341 N346	E340-R344 WeakPolarHBondContact O-CB 3.39Å; E340-R344 PolarHBondContact O-N 3.18Å; K341-R344 PolarHBondContact O-N 3.28Å; R344-N346 PolarHBondContact O-N 2.98Å
345	L	96.2	Very high	96.8	Very high	57 Å²	57	43.5 Å²	43.5	30%	0.298	21%	0.209	S	C	.	.	T	Hydrogen-bonded Turn	trans	-85.8	9.3	177	-65.7	172.3	0	0	0	113.2	L321 F329 K341 M342 Q343 I347	L321-L345 HydrophobicContact CD2-CD1 3.41Å; L321-L345 VanDerWaalsContact CD2-CD1 3.41Å; L321-L345 HydrophobicContact CG-CD1 4.39Å; F329-L345 HydrophobicContact CD1-CD1 4.11Å; F329-L345 HydrophobicContact CE1-CB 4.38Å; F329-L345 HydrophobicContact CE1-CD1 3.93Å; F329-L345 HydrophobicContact CE1-CD2 4Å; F329-L345 HydrophobicContact CE1-CG 4.33Å; F329-L345 HydrophobicContact CE2-CB 4.49Å; F329-L345 HydrophobicContact CZ-CB 4.09Å; F329-L345 HydrophobicContact CZ-CD1 4.45Å; F329-L345 HydrophobicContact CZ-CD2 4.25Å; K341-L345 HydrophobicContact CG-CD1 4.23Å; K341-L345 WeakPolarHBondContact O-CG 3.33Å; K341-L345 PolarHBondContact O-N 2.88Å; K341-L345 VanDerWaalsContact O-N 3.1Å; M342-L345 PolarHBondContact O-N 3.02Å; Q343-L345 PolarHBondContact O-N 3.48Å; L345-I347 HydrophobicContact CB-CD1 4.08Å; L345-I347 HydrophobicContact CB-CG1 4.16Å; L345-I347 HydrophobicContact CD1-CD1 4.36Å; L345-I347 PolarHBondContact O-N 3.41Å
346	N	96.7	Very high	96.4	Very high	76 Å²	76	48.3 Å²	48.3	41%	0.406	23%	0.231	S	C	.	.	T	Hydrogen-bonded Turn	trans	51.9	35.8	-176.4	-176.8	46	0	0	0	112.1	M342 Q343 R344 G348 G400 K401 G402	M342-N346 PolarHBondContact O-N 3.42Å; Q343-N346 PolarHBondContact O-N 3.49Å; R344-N346 PolarHBondContact O-N 2.98Å; N346-G348 PolarHBondContact O-N 3.42Å; N346-G400 PolarHBondContact ND2-O 3.13Å; N346-G400 VanDerWaalsContact ND2-O 3.16Å; N346-K401 PolarHBondContact OD1-NZ 2.79Å; N346-G402 PolarHBondContact O-N 2.77Å
347	I	98.4	Very high	96.2	Very high	8 Å²	8	48.7 Å²	48.7	4%	0.041	23%	0.232	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-68.1	126.9	173.6	-71.3	163.2	0	0	0	107.9	L321 F329 M342 L345 Y349 V350 F367 G402 L404	L321-I347 HydrophobicContact CD2-CD1 4.15Å; F329-I347 HydrophobicContact CD2-CD1 4.15Å; F329-I347 HydrophobicContact CD2-CG1 4.09Å; F329-I347 HydrophobicContact CE2-CG1 4.28Å; F329-I347 HydrophobicContact CG-CD1 4.44Å; M342-I347 HydrophobicContact CB-CB 4.31Å; M342-I347 HydrophobicContact CB-CD1 4.32Å; M342-I347 HydrophobicContact CE-CG2 4Å; M342-I347 HydrophobicContact CG-CD1 4.21Å; M342-I347 WeakPolarHBondContact O-CB 3.46Å; M342-I347 PolarHBondContact O-N 2.91Å; L345-I347 HydrophobicContact CB-CD1 4.08Å; L345-I347 HydrophobicContact CB-CG1 4.16Å; L345-I347 HydrophobicContact CD1-CD1 4.36Å; L345-I347 PolarHBondContact O-N 3.41Å; I347-Y349 WeakPolarHBondContact CG2-O 3.23Å; I347-V350 HydrophobicContact CG2-CG2 4.36Å; I347-F367 HydrophobicContact CG2-CD1 4.34Å; I347-F367 HydrophobicContact CG2-CE1 4.4Å; I347-F367 VanDerWaalsContact O-CD1 3.24Å; I347-F367 WeakPolarHBondContact O-CD1 3.28Å; I347-F367 WeakPolarHBondContact O-CE1 3.42Å; I347-G402 CarbonylContact C-O 3.59Å; I347-G402 VanDerWaalsContact CA-O 3.32Å; I347-G402 WeakPolarHBondContact CA-O 3.34Å; I347-L404 HydrophobicContact CD1-CB 4Å; I347-L404 HydrophobicContact CG2-CB 4.07Å
348	G	97.8	Very high	96.1	Very high	9 Å²	9	47.9 Å²	47.9	9%	0.093	23%	0.234	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-118.5	-11.8	174.3	0	0	0	0	0	112.9	N346 F367 N368 G402	N346-G348 PolarHBondContact O-N 3.42Å; G348-F367 CarbonylContact O-C 3.54Å; G348-F367 WeakPolarHBondContact O-CA 3.47Å; G348-N368 PolarHBondContact O-N 3.31Å; G348-G402 PolarHBondContact N-O 3.37Å
349	Y	98.8	Very high	96.1	Very high	14 Å²	14	46.7 Å²	46.7	6%	0.055	23%	0.228	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-132.9	141.4	-174	-69.7	-104.8	0	0	0	110.8	I347 N368 F392 E395 A396 C399 K401 G402 L403 L404	I347-Y349 WeakPolarHBondContact CG2-O 3.23Å; Y349-N368 CarbonylContact C-O 3.43Å; Y349-N368 VanDerWaalsContact CA-O 3.31Å; Y349-N368 WeakPolarHBondContact CA-O 3.22Å; Y349-N368 HydrophobicContact CD1-CB 3.65Å; Y349-N368 HydrophobicContact CE1-CB 3.7Å; Y349-N368 HydrophobicContact CG-CB 4.24Å; Y349-F392 HydrophobicContact CD1-CD1 4.34Å; Y349-F392 HydrophobicContact CD1-CD2 4.25Å; Y349-F392 AromaticContact CD1-CE1 3.84Å; Y349-F392 HydrophobicContact CD1-CE1 3.84Å; Y349-F392 AromaticContact CD1-CE2 3.73Å; Y349-F392 HydrophobicContact CD1-CE2 3.73Å; Y349-F392 AromaticContact CD1-CZ 3.53Å; Y349-F392 HydrophobicContact CD1-CZ 3.53Å; Y349-F392 HydrophobicContact CE1-CE2 4.08Å; Y349-F392 HydrophobicContact CE1-CZ 4.28Å; Y349-F392 HydrophobicContact CG-CE1 4.48Å; Y349-F392 HydrophobicContact CG-CZ 4.47Å; Y349-E395 HydrophobicContact CE1-CB 4.46Å; Y349-E395 HydrophobicContact CE1-CG 3.93Å; Y349-E395 PolarHBondContact OH-OE1 3.03Å; Y349-A396 HydrophobicContact CD1-CB 4.07Å; Y349-A396 HydrophobicContact CD2-CB 3.38Å; Y349-A396 HydrophobicContact CE2-CB 3.98Å; Y349-A396 HydrophobicContact CG-CB 3.46Å; Y349-A396 VanDerWaalsContact CG-CB 3.46Å; Y349-C399 HydrophobicContact CE2-CB 4.31Å; Y349-C399 PolarHBondContact OH-SG 3.44Å; Y349-K401 HydrophobicContact CD2-CB 3.86Å; Y349-K401 HydrophobicContact CE2-CB 3.95Å; Y349-K401 HydrophobicContact CE2-CG 4.22Å; Y349-G402 PolarHBondContact N-O 2.9Å; Y349-L403 WeakPolarHBondContact O-CA 3.36Å; Y349-L404 PolarHBondContact O-N 3.27Å
350	V	98.8	Very high	96	Very high	2 Å²	2	47.2 Å²	47.2	1%	0.012	23%	0.228	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-134.3	123	-179.4	-175	0	0	0	0	110.8	M342 I347 F367 N368 Y369 K370 L404	M342-V350 HydrophobicContact CE-CG2 3.38Å; I347-V350 HydrophobicContact CG2-CG2 4.36Å; V350-F367 HydrophobicContact CG2-CB 4.02Å; V350-F367 HydrophobicContact CG2-CD2 4.47Å; V350-F367 HydrophobicContact CG2-CG 4.2Å; V350-N368 PolarHBondContact N-O 3.19Å; V350-Y369 HydrophobicContact CB-CD1 3.67Å; V350-Y369 HydrophobicContact CB-CE1 3.84Å; V350-Y369 HydrophobicContact CB-CG 4.43Å; V350-Y369 HydrophobicContact CG1-CD1 4.01Å; V350-Y369 HydrophobicContact CG1-CE1 4.08Å; V350-Y369 HydrophobicContact CG2-CD1 4.31Å; V350-Y369 HydrophobicContact CG2-CE1 4.01Å; V350-Y369 CarbonylContact O-C 3.58Å; V350-Y369 WeakPolarHBondContact O-CA 3.12Å; V350-K370 PolarHBondContact O-N 2.89Å; V350-L404 CarbonylContact C-O 3.56Å; V350-L404 VanDerWaalsContact CA-O 3.28Å; V350-L404 WeakPolarHBondContact CA-O 3.26Å; V350-L404 HydrophobicContact CG1-CD2 4.36Å
351	I	98.9	Very high	96.1	Very high	0 Å²	0	41.1 Å²	41.1	0%	0	20%	0.199	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-101.3	118	168.1	-62.7	177.4	0	0	0	109.2	V353 K370 L372 A389 F392 I393 L403 L404 I405 H406	I351-V353 HydrophobicContact CG2-CG2 3.81Å; I351-K370 CarbonylContact C-O 3.54Å; I351-K370 VanDerWaalsContact CA-O 3.3Å; I351-K370 WeakPolarHBondContact CA-O 3.27Å; I351-K370 HydrophobicContact CG1-CB 4.42Å; I351-L372 HydrophobicContact CG2-CD1 3.63Å; I351-L372 HydrophobicContact CG2-CG 3.91Å; I351-A389 HydrophobicContact CD1-CB 4.36Å; I351-F392 HydrophobicContact CD1-CB 4.45Å; I351-F392 HydrophobicContact CD1-CD1 3.93Å; I351-F392 HydrophobicContact CG1-CD1 3.52Å; I351-F392 HydrophobicContact CG1-CE1 4.02Å; I351-I393 HydrophobicContact CD1-CD1 4.31Å; I351-I393 HydrophobicContact CD1-CG1 3.89Å; I351-L403 HydrophobicContact CD1-CD1 3.98Å; I351-L403 HydrophobicContact CD1-CD2 4.04Å; I351-L403 HydrophobicContact CG1-CD1 4.09Å; I351-L403 HydrophobicContact CG1-CD2 4.14Å; I351-L404 PolarHBondContact N-O 2.85Å; I351-I405 HydrophobicContact CB-CB 4.07Å; I351-I405 HydrophobicContact CB-CD1 4.11Å; I351-I405 HydrophobicContact CB-CG1 3.82Å; I351-I405 HydrophobicContact CD1-CD1 4.26Å; I351-I405 HydrophobicContact CG2-CD1 3.81Å; I351-I405 HydrophobicContact CG2-CG1 3.83Å; I351-I405 WeakPolarHBondContact O-CA 3.22Å; I351-H406 PolarHBondContact O-CD2 3.46Å; I351-H406 PolarHBondContact O-N 3.25Å
352	N	98.6	Very high	96	Very high	0 Å²	0	46.7 Å²	46.7	0%	0	22%	0.22	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-102.7	108.4	172.8	178.9	-15.5	0	0	0	109.6	T354 L357 P358 L359 K370 R371 L372	N352-T354 VanDerWaalsContact C-N 3.25Å; N352-T354 PolarHBondContact O-N 2.8Å; N352-T354 WeakPolarHBondContact OD1-CB 3.46Å; N352-T354 WeakPolarHBondContact OD1-CG2 3.05Å; N352-T354 PolarHBondContact OD1-N 3.34Å; N352-T354 PolarHBondContact OD1-OG1 3.16Å; N352-L357 PolarHBondContact ND2-O 3.06Å; N352-L357 VanDerWaalsContact ND2-O 3.09Å; N352-P358 PolarHBondContact ND2-O 3.45Å; N352-L359 HydrophobicContact CB-CD2 3.83Å; N352-K370 PolarHBondContact N-O 3.49Å; N352-R371 WeakPolarHBondContact O-CA 3.28Å; N352-L372 PolarHBondContact O-N 3.48Å
353	V	98.3	Very high	95.9	Very high	0 Å²	0	53.4 Å²	53.4	0%	0	25%	0.251	C	S	.	.			trans	-91.9	47.8	-179.4	-159.5	0	0	0	0	111.2	I351 L372 A374 L382 I405 H406 C407 R413 I417	I351-V353 HydrophobicContact CG2-CG2 3.81Å; V353-L372 CarbonylContact C-O 3.59Å; V353-L372 WeakPolarHBondContact CA-O 3.39Å; V353-L372 HydrophobicContact CG1-CB 4.18Å; V353-L372 HydrophobicContact CG2-CD1 4.27Å; V353-A374 HydrophobicContact CG1-CB 4.15Å; V353-L382 HydrophobicContact CG1-CD2 4.01Å; V353-I405 HydrophobicContact CG2-CD1 4Å; V353-I405 HydrophobicContact CG2-CG1 3.91Å; V353-H406 PolarHBondContact N-O 3.1Å; V353-C407 HydrophobicContact CB-CB 4.28Å; V353-R413 HydrophobicContact CB-CB 4.2Å; V353-R413 HydrophobicContact CG1-CB 3.79Å; V353-R413 WeakPolarHBondContact O-CD 3.47Å; V353-R413 PolarHBondContact O-NH1 3.02Å; V353-I417 HydrophobicContact CG2-CG1 4.41Å
354	T	92.4	Very high	95.7	Very high	0 Å²	0	53.5 Å²	53.5	0%	0	25%	0.25	C	S	.	.			trans	-137.8	160.6	177.4	78.4	0	0	0	0	111.7	N352 L357 R371 L372 C407	N352-T354 VanDerWaalsContact C-N 3.25Å; N352-T354 PolarHBondContact O-N 2.8Å; N352-T354 WeakPolarHBondContact OD1-CB 3.46Å; N352-T354 WeakPolarHBondContact OD1-CG2 3.05Å; N352-T354 PolarHBondContact OD1-N 3.34Å; N352-T354 PolarHBondContact OD1-OG1 3.16Å; T354-L357 HydrophobicContact CG2-CD1 3.81Å; T354-L357 HydrophobicContact CG2-CG 4.17Å; T354-L357 WeakPolarHBondContact OG1-CB 3.1Å; T354-L357 PolarHBondContact OG1-N 2.78Å; T354-R371 WeakPolarHBondContact O-CD 3.36Å; T354-R371 WeakPolarHBondContact O-CG 3.29Å; T354-L372 PolarHBondContact N-O 3.22Å; T354-C407 HydrophobicContact CG2-CB 4.06Å
355	T	90.6	Very high	95.6	Very high	64 Å²	64	47.5 Å²	47.5	39%	0.393	25%	0.25	S	C	.	.	S	Bend	trans	-88.9	-33.4	174.2	51.6	0	0	0	0	113	P373 T375	T355-P373 HydrophobicContact CG2-CB 4.04Å; T355-T375 HydrophobicContact CG2-CG2 4.25Å
356	H	87.9	Confident	95.5	Very high	108 Å²	108	48 Å²	48	50%	0.5	25%	0.252	S	S	.	.	S	Bend	trans	-109	-28.2	-164.2	59.2	-86.2	0	0	0	114.3
357	L	92	Very high	95.5	Very high	11 Å²	11	45 Å²	45	6%	0.058	24%	0.235	C	C	.	.	S	Bend	trans	-71.6	137.4	-179.2	-61.3	179.7	0	0	0	110	E333 N352 T354 R371 Q408	E333-L357 HydrophobicContact CB-CD1 3.73Å; E333-L357 WeakPolarHBondContact OE2-CD2 3.27Å; N352-L357 PolarHBondContact ND2-O 3.06Å; N352-L357 VanDerWaalsContact ND2-O 3.09Å; T354-L357 HydrophobicContact CG2-CD1 3.81Å; T354-L357 HydrophobicContact CG2-CG 4.17Å; T354-L357 WeakPolarHBondContact OG1-CB 3.1Å; T354-L357 PolarHBondContact OG1-N 2.78Å; L357-R371 PolarHBondContact O-NH2 3.49Å; L357-Q408 HydrophobicContact CD1-CB 4.4Å
358	P	94.9	Very high	95.5	Very high	65 Å²	65	48.6 Å²	48.6	42%	0.422	25%	0.254	S	S	.	.			trans	-64.3	163.8	177.7	30.7	-36.9	0	0	0	111.5	N352 Y360	N352-P358 PolarHBondContact ND2-O 3.45Å; P358-Y360 VanDerWaalsContact C-N 3.34Å; P358-Y360 HydrophobicContact CG-CD1 3.76Å; P358-Y360 HydrophobicContact CG-CE1 3.36Å; P358-Y360 HydrophobicContact CG-CE2 4.25Å; P358-Y360 HydrophobicContact CG-CG 4.37Å; P358-Y360 PolarHBondContact O-N 2.97Å
359	L	96.8	Very high	95.5	Very high	39 Å²	39	50 Å²	50	20%	0.204	26%	0.257	C	S	.	.			trans	-82.3	87.5	165.1	-58.9	179.3	0	0	0	106.5	N352 H361 Y362 Y369 R371	N352-L359 HydrophobicContact CB-CD2 3.83Å; L359-H361 PolarHBondContact O-N 3.15Å; L359-Y362 HydrophobicContact CB-CD2 4.07Å; L359-Y362 HydrophobicContact CB-CG 4.29Å; L359-Y362 HydrophobicContact CD1-CD2 3.81Å; L359-Y362 HydrophobicContact CD1-CE2 4.08Å; L359-Y362 WeakPolarHBondContact O-CB 3.48Å; L359-Y362 PolarHBondContact O-N 2.99Å; L359-Y362 VanDerWaalsContact O-N 3.16Å; L359-Y369 HydrophobicContact CB-CD1 3.83Å; L359-Y369 HydrophobicContact CB-CE1 4.06Å; L359-Y369 HydrophobicContact CB-CG 4.27Å; L359-Y369 HydrophobicContact CD1-CD1 4.46Å; L359-Y369 HydrophobicContact CD1-CG 4.25Å; L359-Y369 HydrophobicContact CD2-CD1 3.93Å; L359-Y369 HydrophobicContact CD2-CG 4.44Å; L359-Y369 HydrophobicContact CG-CD1 4.27Å; L359-R371 HydrophobicContact CD2-CB 4.37Å
360	Y	96.2	Very high	95.5	Very high	45 Å²	45	51.5 Å²	51.5	18%	0.176	26%	0.264	C	S	.	.	T	Hydrogen-bonded Turn	trans	-56.4	134.5	-177.1	-60.9	-74	0	0	0	111	A336 Q337 P358 Y362 Y369	A336-Y360 HydrophobicContact CB-CD2 3.96Å; A336-Y360 HydrophobicContact CB-CE2 4.48Å; A336-Y360 WeakPolarHBondContact O-CB 3.35Å; Q337-Y360 HydrophobicContact CG-CD1 3.56Å; Q337-Y360 HydrophobicContact CG-CD2 3.85Å; Q337-Y360 HydrophobicContact CG-CE1 3.54Å; Q337-Y360 HydrophobicContact CG-CE2 3.86Å; Q337-Y360 HydrophobicContact CG-CG 3.7Å; Q337-Y360 VanDerWaalsContact NE2-CZ 3.26Å; Q337-Y360 PolarHBondContact NE2-OH 3.31Å; Q337-Y360 VanDerWaalsContact NE2-OH 3.12Å; P358-Y360 VanDerWaalsContact C-N 3.34Å; P358-Y360 HydrophobicContact CG-CD1 3.76Å; P358-Y360 HydrophobicContact CG-CE1 3.36Å; P358-Y360 HydrophobicContact CG-CE2 4.25Å; P358-Y360 HydrophobicContact CG-CG 4.37Å; P358-Y360 PolarHBondContact O-N 2.97Å; Y360-Y362 VanDerWaalsContact C-N 3.26Å; Y360-Y362 PolarHBondContact O-N 3.13Å; Y360-Y369 WeakPolarHBondContact O-CE1 3.43Å; Y360-Y369 VanDerWaalsContact O-CZ 3.31Å; Y360-Y369 PolarHBondContact O-OH 3.19Å
361	H	96.9	Very high	95.5	Very high	29 Å²	29	55.9 Å²	55.9	13%	0.134	28%	0.28	C	S	.	.	T	Hydrogen-bonded Turn	trans	68.8	12.3	-178.1	-44.3	-66.9	0	0	0	115.8	Q337 L359 E363 K364 I366 F367 Y369	Q337-H361 PolarHBondContact O-CE1 2.89Å; Q337-H361 PolarHBondContact O-NE2 3.16Å; L359-H361 PolarHBondContact O-N 3.15Å; H361-E363 PolarHBondContact O-N 2.94Å; H361-K364 HydrophobicContact CB-CD 4.19Å; H361-K364 HydrophobicContact CB-CG 4.42Å; H361-K364 WeakPolarHBondContact O-CB 3.38Å; H361-K364 PolarHBondContact O-N 2.91Å; H361-I366 HydrophobicContact CB-CD1 4.42Å; H361-F367 HydrophobicContact CB-CE2 4.37Å; H361-Y369 VanDerWaalsContact C-OH 3.3Å
362	Y	95.4	Very high	95.5	Very high	149 Å²	149	55.9 Å²	55.9	58%	0.584	28%	0.28	S	S	*	.	G	3₁₀ helix	trans	-57.5	-38.9	179.5	-174.5	-93.6	0	0	0	112.4	L359 Y360 K364 G365 Y369	L359-Y362 HydrophobicContact CB-CD2 4.07Å; L359-Y362 HydrophobicContact CB-CG 4.29Å; L359-Y362 HydrophobicContact CD1-CD2 3.81Å; L359-Y362 HydrophobicContact CD1-CE2 4.08Å; L359-Y362 WeakPolarHBondContact O-CB 3.48Å; L359-Y362 PolarHBondContact O-N 2.99Å; L359-Y362 VanDerWaalsContact O-N 3.16Å; Y360-Y362 VanDerWaalsContact C-N 3.26Å; Y360-Y362 PolarHBondContact O-N 3.13Å; Y362-K364 PolarHBondContact O-N 3.48Å; Y362-K364 VanDerWaalsContact O-N 3.13Å; Y362-G365 PolarHBondContact O-N 3.37Å; Y362-G365 VanDerWaalsContact O-N 3.17Å; Y362-Y369 AromaticContact CD2-CD2 3.49Å; Y362-Y369 HydrophobicContact CD2-CD2 3.49Å; Y362-Y369 VanDerWaalsContact CD2-CD2 3.49Å; Y362-Y369 AromaticContact CD2-CE2 3.88Å; Y362-Y369 HydrophobicContact CD2-CE2 3.88Å; Y362-Y369 AromaticContact CD2-CG 3.98Å; Y362-Y369 HydrophobicContact CD2-CG 3.98Å; Y362-Y369 HydrophobicContact CE2-CD2 4.07Å; Y362-Y369 PolarHBondContact N-OH 3.46Å
363	E	94.4	Very high	95.3	Very high	142 Å²	142	58.7 Å²	58.7	66%	0.664	30%	0.298	S	S	*	.	G	3₁₀ helix	trans	-62.1	-19.1	178.2	72.4	-69.2	163.8	0	0	113.8	H361	H361-E363 PolarHBondContact O-N 2.94Å
364	K	93.4	Very high	95	Very high	110 Å²	110	58.7 Å²	58.7	48%	0.478	30%	0.298	S	S	.	.	G	3₁₀ helix	trans	-83.7	-14.5	-179.8	-56.5	-170.5	-176.8	-167.4	0	113.1	L339 H361 Y362 I366	L339-K364 HydrophobicContact CD2-CD 4.05Å; L339-K364 VanDerWaalsContact CD2-NZ 3.29Å; H361-K364 HydrophobicContact CB-CD 4.19Å; H361-K364 HydrophobicContact CB-CG 4.42Å; H361-K364 WeakPolarHBondContact O-CB 3.38Å; H361-K364 PolarHBondContact O-N 2.91Å; Y362-K364 PolarHBondContact O-N 3.48Å; Y362-K364 VanDerWaalsContact O-N 3.13Å; K364-I366 HydrophobicContact CB-CD1 4.14Å; K364-I366 HydrophobicContact CB-CG1 3.98Å; K364-I366 HydrophobicContact CB-CG2 4.33Å; K364-I366 HydrophobicContact CD-CD1 4.42Å; K364-I366 PolarHBondContact O-N 3.05Å
365	G	93.5	Very high	94.6	Very high	70 Å²	70	61.3 Å²	61.3	72%	0.722	32%	0.315	S	S	*	.	T	Hydrogen-bonded Turn	trans	63.9	22.4	176.4	0	0	0	0	0	115.3	Y362	Y362-G365 PolarHBondContact O-N 3.37Å; Y362-G365 VanDerWaalsContact O-N 3.17Å
366	I	94.5	Very high	94.1	Very high	68 Å²	68	62 Å²	62	35%	0.349	32%	0.316	S	S	.	.			trans	-95.7	-21.2	-173.6	51.4	173.1	0	0	0	114.2	L339 H361 K364	L339-I366 HydrophobicContact CD1-CD1 3.21Å; H361-I366 HydrophobicContact CB-CD1 4.42Å; K364-I366 HydrophobicContact CB-CD1 4.14Å; K364-I366 HydrophobicContact CB-CG1 3.98Å; K364-I366 HydrophobicContact CB-CG2 4.33Å; K364-I366 HydrophobicContact CD-CD1 4.42Å; K364-I366 PolarHBondContact O-N 3.05Å
367	F	97.6	Very high	93.2	Very high	13 Å²	13	58.6 Å²	58.6	6%	0.057	31%	0.305	C	S	.	.	S	Bend	trans	-126.1	148.9	-179.9	-48.5	-65.5	0	0	0	110	L339 M342 Q343 I347 G348 V350 H361 Y369	L339-F367 HydrophobicContact CD1-CE2 3.78Å; L339-F367 HydrophobicContact CD1-CZ 3.75Å; M342-F367 HydrophobicContact CB-CE1 4.17Å; M342-F367 HydrophobicContact CB-CZ 3.71Å; M342-F367 HydrophobicContact CE-CD1 4.29Å; M342-F367 HydrophobicContact CE-CD2 3.82Å; M342-F367 HydrophobicContact CE-CE1 4.03Å; M342-F367 HydrophobicContact CE-CE2 3.51Å; M342-F367 HydrophobicContact CE-CG 4.2Å; M342-F367 HydrophobicContact CE-CZ 3.63Å; M342-F367 HydrophobicContact SD-CE2 4.14Å; M342-F367 HydrophobicContact SD-CZ 4.21Å; Q343-F367 HydrophobicContact CG-CZ 4.43Å; I347-F367 HydrophobicContact CG2-CD1 4.34Å; I347-F367 HydrophobicContact CG2-CE1 4.4Å; I347-F367 VanDerWaalsContact O-CD1 3.24Å; I347-F367 WeakPolarHBondContact O-CD1 3.28Å; I347-F367 WeakPolarHBondContact O-CE1 3.42Å; G348-F367 CarbonylContact O-C 3.54Å; G348-F367 WeakPolarHBondContact O-CA 3.47Å; V350-F367 HydrophobicContact CG2-CB 4.02Å; V350-F367 HydrophobicContact CG2-CD2 4.47Å; V350-F367 HydrophobicContact CG2-CG 4.2Å; H361-F367 HydrophobicContact CB-CE2 4.37Å; F367-Y369 HydrophobicContact CB-CD2 4.35Å; F367-Y369 HydrophobicContact CB-CE2 3.72Å; F367-Y369 HydrophobicContact CD2-CE2 4.47Å; F367-Y369 WeakPolarHBondContact CD2-OH 3.45Å; F367-Y369 WeakPolarHBondContact O-CD2 3.46Å; F367-Y369 VanDerWaalsContact O-CE2 3.24Å; F367-Y369 WeakPolarHBondContact O-CE2 3.37Å
368	N	98	Very high	92	Very high	83 Å²	83	63.9 Å²	63.9	44%	0.444	33%	0.333	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-86.3	130.7	167.1	-65.4	-54.1	0	0	0	109.1	G348 Y349 V350 F392	G348-N368 PolarHBondContact O-N 3.31Å; Y349-N368 CarbonylContact C-O 3.43Å; Y349-N368 VanDerWaalsContact CA-O 3.31Å; Y349-N368 WeakPolarHBondContact CA-O 3.22Å; Y349-N368 HydrophobicContact CD1-CB 3.65Å; Y349-N368 HydrophobicContact CE1-CB 3.7Å; Y349-N368 HydrophobicContact CG-CB 4.24Å; V350-N368 PolarHBondContact N-O 3.19Å; N368-F392 HydrophobicContact CB-CE2 4.42Å; N368-F392 HydrophobicContact CB-CZ 4.02Å; N368-F392 WeakPolarHBondContact O-CZ 3.46Å
369	Y	98.5	Very high	90.8	Very high	37 Å²	37	69.5 Å²	69.5	15%	0.145	35%	0.35	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-113	144.7	-176.8	-66	-99.5	0	0	0	112.1	V350 L359 Y360 H361 Y362 F367	V350-Y369 HydrophobicContact CB-CD1 3.67Å; V350-Y369 HydrophobicContact CB-CE1 3.84Å; V350-Y369 HydrophobicContact CB-CG 4.43Å; V350-Y369 HydrophobicContact CG1-CD1 4.01Å; V350-Y369 HydrophobicContact CG1-CE1 4.08Å; V350-Y369 HydrophobicContact CG2-CD1 4.31Å; V350-Y369 HydrophobicContact CG2-CE1 4.01Å; V350-Y369 CarbonylContact O-C 3.58Å; V350-Y369 WeakPolarHBondContact O-CA 3.12Å; L359-Y369 HydrophobicContact CB-CD1 3.83Å; L359-Y369 HydrophobicContact CB-CE1 4.06Å; L359-Y369 HydrophobicContact CB-CG 4.27Å; L359-Y369 HydrophobicContact CD1-CD1 4.46Å; L359-Y369 HydrophobicContact CD1-CG 4.25Å; L359-Y369 HydrophobicContact CD2-CD1 3.93Å; L359-Y369 HydrophobicContact CD2-CG 4.44Å; L359-Y369 HydrophobicContact CG-CD1 4.27Å; Y360-Y369 WeakPolarHBondContact O-CE1 3.43Å; Y360-Y369 VanDerWaalsContact O-CZ 3.31Å; Y360-Y369 PolarHBondContact O-OH 3.19Å; H361-Y369 VanDerWaalsContact C-OH 3.3Å; Y362-Y369 AromaticContact CD2-CD2 3.49Å; Y362-Y369 HydrophobicContact CD2-CD2 3.49Å; Y362-Y369 VanDerWaalsContact CD2-CD2 3.49Å; Y362-Y369 AromaticContact CD2-CE2 3.88Å; Y362-Y369 HydrophobicContact CD2-CE2 3.88Å; Y362-Y369 AromaticContact CD2-CG 3.98Å; Y362-Y369 HydrophobicContact CD2-CG 3.98Å; Y362-Y369 HydrophobicContact CE2-CD2 4.07Å; Y362-Y369 PolarHBondContact N-OH 3.46Å; F367-Y369 HydrophobicContact CB-CD2 4.35Å; F367-Y369 HydrophobicContact CB-CE2 3.72Å; F367-Y369 HydrophobicContact CD2-CE2 4.47Å; F367-Y369 WeakPolarHBondContact CD2-OH 3.45Å; F367-Y369 WeakPolarHBondContact O-CD2 3.46Å; F367-Y369 VanDerWaalsContact O-CE2 3.24Å; F367-Y369 WeakPolarHBondContact O-CE2 3.37Å
370	K	98.6	Very high	90.2	Very high	47 Å²	47	69.1 Å²	69.1	20%	0.204	35%	0.348	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-131.2	123.3	164	-178.5	170.4	-72.8	-63.5	0	109.3	V350 I351 N352 L372 E388 F392	V350-K370 PolarHBondContact O-N 2.89Å; I351-K370 CarbonylContact C-O 3.54Å; I351-K370 VanDerWaalsContact CA-O 3.3Å; I351-K370 WeakPolarHBondContact CA-O 3.27Å; I351-K370 HydrophobicContact CG1-CB 4.42Å; N352-K370 PolarHBondContact N-O 3.49Å; K370-L372 HydrophobicContact CD-CD2 4.1Å; K370-L372 HydrophobicContact CG-CD2 3.98Å; K370-E388 HydrophobicContact CD-CG 3.94Å; K370-E388 WeakPolarHBondContact CD-OE1 3.38Å; K370-E388 IonicContact NZ-OE1 2.95Å; K370-E388 PolarHBondContact NZ-OE1 3.31Å; K370-F392 HydrophobicContact CB-CD1 3.67Å; K370-F392 HydrophobicContact CB-CD2 4.26Å; K370-F392 HydrophobicContact CB-CE1 3.55Å; K370-F392 HydrophobicContact CB-CE2 4.16Å; K370-F392 HydrophobicContact CB-CG 4.01Å; K370-F392 HydrophobicContact CB-CZ 3.79Å; K370-F392 HydrophobicContact CD-CB 3.82Å; K370-F392 HydrophobicContact CD-CD1 4.22Å; K370-F392 HydrophobicContact CD-CD2 4.28Å; K370-F392 HydrophobicContact CD-CG 3.87Å
371	R	98.5	Very high	90	Very high	93 Å²	93	70.5 Å²	70.5	35%	0.351	36%	0.358	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-95.6	127.8	171.4	-178.8	174.2	-76.6	157.4	-2.1	109.1	N352 T354 L357 L359 P373	N352-R371 WeakPolarHBondContact O-CA 3.28Å; T354-R371 WeakPolarHBondContact O-CD 3.36Å; T354-R371 WeakPolarHBondContact O-CG 3.29Å; L357-R371 PolarHBondContact O-NH2 3.49Å; L359-R371 HydrophobicContact CD2-CB 4.37Å; R371-P373 WeakPolarHBondContact O-CD 3.13Å
372	L	98.1	Very high	89.9	Confident	0 Å²	0	69.1 Å²	69.1	0%	0	35%	0.352	C	S	.	.			trans	-105.5	95.4	168.6	-53.3	179.2	0	0	0	107.1	I351 N352 V353 T354 K370 A374 Y385 A389 I417	I351-L372 HydrophobicContact CG2-CD1 3.63Å; I351-L372 HydrophobicContact CG2-CG 3.91Å; N352-L372 PolarHBondContact O-N 3.48Å; V353-L372 CarbonylContact C-O 3.59Å; V353-L372 WeakPolarHBondContact CA-O 3.39Å; V353-L372 HydrophobicContact CG1-CB 4.18Å; V353-L372 HydrophobicContact CG2-CD1 4.27Å; T354-L372 PolarHBondContact N-O 3.22Å; K370-L372 HydrophobicContact CD-CD2 4.1Å; K370-L372 HydrophobicContact CG-CD2 3.98Å; L372-A374 PolarHBondContact O-N 3.32Å; L372-Y385 HydrophobicContact CB-CD1 4.39Å; L372-Y385 HydrophobicContact CB-CD2 4.32Å; L372-Y385 HydrophobicContact CB-CG 4.13Å; L372-Y385 HydrophobicContact CD2-CD1 4.04Å; L372-Y385 HydrophobicContact CD2-CG 4.21Å; L372-A389 HydrophobicContact CD1-CB 3.79Å; L372-I417 HydrophobicContact CD1-CD1 4.32Å; L372-I417 HydrophobicContact CD1-CG1 4.42Å
373	P	95.1	Very high	89.9	Confident	59 Å²	59	64.8 Å²	64.8	38%	0.383	33%	0.334	S	S	.	.			trans	-70.5	95	-171.6	26.2	-30.5	0	0	0	110.2	T355 R371 Y385	T355-P373 HydrophobicContact CG2-CB 4.04Å; R371-P373 WeakPolarHBondContact O-CD 3.13Å; P373-Y385 WeakPolarHBondContact CG-OH 3.38Å; P373-Y385 PolarHBondContact O-OH 2.99Å
374	A	91.8	Very high	90	Very high	0 Å²	0	63.4 Å²	63.4	0%	0	33%	0.328	C	S	.	.			trans	-138	136	-176.4	0	0	0	0	0	112.4	V353 L372 Q380 L382 Y385 R413	V353-A374 HydrophobicContact CG1-CB 4.15Å; L372-A374 PolarHBondContact O-N 3.32Å; A374-Q380 HydrophobicContact CB-CG 3.95Å; A374-L382 HydrophobicContact CB-CD2 3.46Å; A374-L382 VanDerWaalsContact CB-CD2 3.46Å; A374-Y385 HydrophobicContact CB-CE2 4.16Å; A374-R413 WeakPolarHBondContact O-CD 3.44Å; A374-R413 PolarHBondContact O-NH1 3.19Å
375	T	84.1	Confident	90.2	Very high	56 Å²	56	59.5 Å²	59.5	34%	0.344	31%	0.31	S	S	.	.			trans	-91	154	170.6	62.9	0	0	0	0	110.6	T355 S377 Q380	T355-T375 HydrophobicContact CG2-CG2 4.25Å; T375-S377 PolarHBondContact O-N 3.16Å; T375-S377 PolarHBondContact OG1-OG 3.15Å; T375-Q380 WeakPolarHBondContact O-CB 3.37Å; T375-Q380 VanDerWaalsContact O-CG 3.3Å; T375-Q380 WeakPolarHBondContact O-CG 3.18Å; T375-Q380 PolarHBondContact OG1-OE1 3.44Å
376	D	79.8	Confident	90.4	Very high	78 Å²	78	56.4 Å²	56.4	42%	0.417	28%	0.277	S	S	.	.	S	Bend	trans	-85	54.9	174.7	-161.4	7.6	0	0	0	110.9	S412 R413 N447 F450	D376-S412 WeakPolarHBondContact OD1-CB 3.15Å; D376-S412 PolarHBondContact OD1-OG 3.45Å; D376-S412 WeakPolarHBondContact OD2-CB 3.47Å; D376-S412 PolarHBondContact OD2-OG 3.36Å; D376-R413 HydrophobicContact CB-CG 4.11Å; D376-N447 PolarHBondContact OD1-ND2 2.85Å; D376-F450 VanDerWaalsContact OD1-CE2 3.29Å; D376-F450 WeakPolarHBondContact OD1-CE2 3.4Å
377	S	70.1	Confident	90.5	Very high	37 Å²	37	57 Å²	57	26%	0.259	28%	0.278	S	S	.	.	S	Bend	trans	-107.2	157.3	-176.3	70.1	0	0	0	0	111.9	T375 K379 Q380 N449	T375-S377 PolarHBondContact O-N 3.16Å; T375-S377 PolarHBondContact OG1-OG 3.15Å; S377-K379 PolarHBondContact O-N 3.3Å; S377-K379 VanDerWaalsContact O-N 3.1Å; S377-Q380 PolarHBondContact O-N 3.01Å; S377-Q380 PolarHBondContact OG-N 3.5Å; S377-N449 PolarHBondContact O-ND2 3.16Å
378	N	64.9	Low	90.4	Very high	122 Å²	122	59.9 Å²	59.9	65%	0.652	29%	0.292	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.2	-0.1	175.3	64.4	-7.6	0	0	0	114.4	N449	N378-N449 HydrophobicContact CB-CB 4.45Å; N378-N449 VanDerWaalsContact O-CB 3.32Å; N378-N449 WeakPolarHBondContact O-CB 3.18Å
379	K	71.3	Confident	90.4	Very high	182 Å²	182	56 Å²	56	79%	0.791	27%	0.271	S	S	*	.	T	Hydrogen-bonded Turn	trans	-117.4	-8.8	178	-65.9	177.4	-176.3	179.8	0	113.1	S377 N381	S377-K379 PolarHBondContact O-N 3.3Å; S377-K379 VanDerWaalsContact O-N 3.1Å; K379-N381 PolarHBondContact O-N 2.95Å
380	Q	83.9	Confident	90.4	Very high	31 Å²	31	54.3 Å²	54.3	15%	0.145	27%	0.265	C	S	.	.			trans	-68.3	127.2	-176.3	-178.1	71.3	50.3	0	0	110.3	A374 T375 S377 N449 F450 Q453	A374-Q380 HydrophobicContact CB-CG 3.95Å; T375-Q380 WeakPolarHBondContact O-CB 3.37Å; T375-Q380 VanDerWaalsContact O-CG 3.3Å; T375-Q380 WeakPolarHBondContact O-CG 3.18Å; T375-Q380 PolarHBondContact OG1-OE1 3.44Å; S377-Q380 PolarHBondContact O-N 3.01Å; S377-Q380 PolarHBondContact OG-N 3.5Å; Q380-N449 PolarHBondContact N-ND2 3.15Å; Q380-N449 PolarHBondContact O-ND2 3.21Å; Q380-F450 HydrophobicContact CB-CE1 3.85Å; Q380-F450 HydrophobicContact CB-CZ 4.06Å; Q380-F450 HydrophobicContact CG-CE1 4.13Å; Q380-F450 HydrophobicContact CG-CZ 4.24Å; Q380-F450 WeakPolarHBondContact O-CE1 3.4Å; Q380-Q453 PolarHBondContact O-NE2 3.21Å
381	N	91.9	Very high	90.3	Very high	74 Å²	74	57.8 Å²	57.8	40%	0.396	28%	0.281	S	S	.	.			trans	-85	112	167.6	-179.4	-3	0	0	0	108.8	K379 R383 Q384	K379-N381 PolarHBondContact O-N 2.95Å; N381-R383 WeakPolarHBondContact OD1-CB 3.45Å; N381-R383 PolarHBondContact OD1-N 3.37Å; N381-Q384 PolarHBondContact O-NE2 3.39Å; N381-Q384 PolarHBondContact OD1-N 2.77Å
382	L	95.1	Very high	90.3	Very high	0 Å²	0	54.1 Å²	54.1	0%	0	27%	0.268	C	S	.	.			trans	-94.1	-24	171.5	-85.3	-176.3	0	0	0	112.6	V353 A374 Q384 Y385 F386 R413 T416 I417 F450	V353-L382 HydrophobicContact CG1-CD2 4.01Å; A374-L382 HydrophobicContact CB-CD2 3.46Å; A374-L382 VanDerWaalsContact CB-CD2 3.46Å; L382-Q384 PolarHBondContact O-N 2.69Å; L382-Y385 HydrophobicContact CD2-CD2 4.02Å; L382-Y385 PolarHBondContact O-N 3.03Å; L382-F386 HydrophobicContact CB-CE1 4.22Å; L382-F386 VanDerWaalsContact O-CD1 3.29Å; L382-F386 WeakPolarHBondContact O-CD1 3.08Å; L382-R413 HydrophobicContact CD1-CB 4.39Å; L382-R413 HydrophobicContact CD1-CG 4.42Å; L382-T416 HydrophobicContact CD1-CG2 3.9Å; L382-I417 HydrophobicContact CD2-CD1 4.47Å; L382-F450 HydrophobicContact CB-CD1 4.24Å; L382-F450 HydrophobicContact CB-CE1 4.19Å; L382-F450 HydrophobicContact CD1-CD1 3.67Å; L382-F450 HydrophobicContact CD1-CD2 3.75Å; L382-F450 HydrophobicContact CD1-CE1 3.5Å; L382-F450 HydrophobicContact CD1-CE2 3.59Å; L382-F450 HydrophobicContact CD1-CG 3.81Å; L382-F450 HydrophobicContact CD1-CZ 3.48Å; L382-F450 VanDerWaalsContact CD1-CZ 3.48Å; L382-F450 HydrophobicContact CG-CD1 3.96Å; L382-F450 HydrophobicContact CG-CE1 3.52Å; L382-F450 HydrophobicContact CG-CE2 4.41Å; L382-F450 HydrophobicContact CG-CZ 3.79Å
383	R	95.3	Very high	90.3	Very high	59 Å²	59	54.1 Å²	54.1	22%	0.223	27%	0.268	C	S	.	.	G	3₁₀ helix	trans	-55.5	-34.7	178.4	-63.3	-171.7	63.7	-172.3	-4.6	112.7	N381 Y385 F386 Q453 E456 D460	N381-R383 WeakPolarHBondContact OD1-CB 3.45Å; N381-R383 PolarHBondContact OD1-N 3.37Å; R383-Y385 PolarHBondContact O-N 3.09Å; R383-F386 HydrophobicContact CB-CD2 4.46Å; R383-F386 HydrophobicContact CB-CE2 4.41Å; R383-F386 HydrophobicContact CG-CD2 4.48Å; R383-F386 HydrophobicContact CG-CE2 3.98Å; R383-F386 HydrophobicContact CG-CZ 4.16Å; R383-F386 WeakPolarHBondContact O-CB 3.46Å; R383-F386 PolarHBondContact O-N 2.8Å; R383-Q453 HydrophobicContact CG-CB 3.62Å; R383-Q453 HydrophobicContact CG-CG 3.85Å; R383-Q453 VanDerWaalsContact N-OE1 3.14Å; R383-E456 IonicContact NH1-OE2 2.89Å; R383-E456 PolarHBondContact NH1-OE2 3.03Å; R383-D460 IonicContact CZ-OD2 2.87Å; R383-D460 IonicContact NH1-OD2 3.48Å; R383-D460 IonicContact NH2-OD2 3.6Å; R383-D460 PolarHBondContact NH2-OD2 2.8Å
384	Q	96.3	Very high	90.3	Very high	112 Å²	112	53.3 Å²	53.3	52%	0.523	26%	0.259	S	S	.	.	G	3₁₀ helix	trans	-57	-23	177.5	73.3	-175.8	-59.7	0	0	113.6	N381 L382	N381-Q384 PolarHBondContact O-NE2 3.39Å; N381-Q384 PolarHBondContact OD1-N 2.77Å; L382-Q384 PolarHBondContact O-N 2.69Å
385	Y	98.1	Very high	90.5	Very high	29 Å²	29	57.8 Å²	57.8	11%	0.114	28%	0.28	C	S	.	.	G	3₁₀ helix	trans	-100.3	-2.4	-179	-59.2	-58.9	0	0	0	113.8	L372 P373 A374 L382 R383 A389	L372-Y385 HydrophobicContact CB-CD1 4.39Å; L372-Y385 HydrophobicContact CB-CD2 4.32Å; L372-Y385 HydrophobicContact CB-CG 4.13Å; L372-Y385 HydrophobicContact CD2-CD1 4.04Å; L372-Y385 HydrophobicContact CD2-CG 4.21Å; P373-Y385 WeakPolarHBondContact CG-OH 3.38Å; P373-Y385 PolarHBondContact O-OH 2.99Å; A374-Y385 HydrophobicContact CB-CE2 4.16Å; L382-Y385 HydrophobicContact CD2-CD2 4.02Å; L382-Y385 PolarHBondContact O-N 3.03Å; R383-Y385 PolarHBondContact O-N 3.09Å; Y385-A389 WeakPolarHBondContact O-CB 3.06Å; Y385-A389 PolarHBondContact O-N 3.42Å
386	F	97.4	Very high	91	Very high	5 Å²	5	55.1 Å²	55.1	2%	0.022	26%	0.264	C	S	.	.	H	α-helix	trans	-60.8	-52.7	-173.4	-78.1	6.4	0	0	0	111.4	L382 R383 E388 A389 F390 T416 I417 A420 L454 F457	L382-F386 HydrophobicContact CB-CE1 4.22Å; L382-F386 VanDerWaalsContact O-CD1 3.29Å; L382-F386 WeakPolarHBondContact O-CD1 3.08Å; R383-F386 HydrophobicContact CB-CD2 4.46Å; R383-F386 HydrophobicContact CB-CE2 4.41Å; R383-F386 HydrophobicContact CG-CD2 4.48Å; R383-F386 HydrophobicContact CG-CE2 3.98Å; R383-F386 HydrophobicContact CG-CZ 4.16Å; R383-F386 WeakPolarHBondContact O-CB 3.46Å; R383-F386 PolarHBondContact O-N 2.8Å; F386-E388 PolarHBondContact O-N 3.06Å; F386-A389 PolarHBondContact O-N 2.98Å; F386-F390 HydrophobicContact CB-CD2 4.46Å; F386-F390 HydrophobicContact CB-CE1 4.33Å; F386-F390 HydrophobicContact CB-CE2 3.7Å; F386-F390 HydrophobicContact CB-CZ 3.63Å; F386-F390 HydrophobicContact CD2-CZ 4.22Å; F386-F390 HydrophobicContact CG-CE2 4.41Å; F386-F390 AromaticContact CG-CZ 3.92Å; F386-F390 HydrophobicContact CG-CZ 3.92Å; F386-F390 WeakPolarHBondContact O-CB 3.39Å; F386-F390 WeakPolarHBondContact O-CD1 3.29Å; F386-F390 WeakPolarHBondContact O-CD2 3.09Å; F386-F390 WeakPolarHBondContact O-CG 3.26Å; F386-F390 PolarHBondContact O-N 3.31Å; F386-T416 HydrophobicContact CE1-CG2 4.39Å; F386-T416 HydrophobicContact CZ-CG2 4.33Å; F386-I417 HydrophobicContact CD1-CD1 3.7Å; F386-I417 HydrophobicContact CE1-CD1 3.79Å; F386-A420 HydrophobicContact CD1-CB 4.23Å; F386-A420 HydrophobicContact CD2-CB 3.82Å; F386-A420 HydrophobicContact CE1-CB 3.94Å; F386-A420 HydrophobicContact CE2-CB 3.49Å; F386-A420 VanDerWaalsContact CE2-CB 3.49Å; F386-A420 HydrophobicContact CG-CB 4.18Å; F386-A420 HydrophobicContact CZ-CB 3.56Å; F386-L454 HydrophobicContact CE2-CD2 4.5Å; F386-L454 HydrophobicContact CZ-CD2 4.16Å; F386-F457 AromaticContact CD2-CD1 3.99Å; F386-F457 HydrophobicContact CD2-CD1 3.99Å; F386-F457 AromaticContact CD2-CD2 3.82Å; F386-F457 HydrophobicContact CD2-CD2 3.82Å; F386-F457 HydrophobicContact CD2-CE1 4.08Å; F386-F457 AromaticContact CD2-CE2 3.9Å; F386-F457 HydrophobicContact CD2-CE2 3.9Å; F386-F457 AromaticContact CD2-CG 3.87Å; F386-F457 HydrophobicContact CD2-CG 3.87Å; F386-F457 HydrophobicContact CD2-CZ 4.04Å; F386-F457 HydrophobicContact CE2-CB 3.99Å; F386-F457 AromaticContact CE2-CD1 3.85Å; F386-F457 HydrophobicContact CE2-CD1 3.85Å; F386-F457 HydrophobicContact CE2-CD2 4.12Å; F386-F457 HydrophobicContact CE2-CE1 4.35Å; F386-F457 AromaticContact CE2-CG 3.72Å; F386-F457 HydrophobicContact CE2-CG 3.72Å
387	E	95.5	Very high	91.7	Very high	81 Å²	81	53.7 Å²	53.7	38%	0.379	25%	0.254	S	S	.	.	H	α-helix	trans	-61.5	-47.8	-178.6	-154.9	66	-170.9	0	0	111.8	A389 F390 E391 K424	E387-A389 VanDerWaalsContact C-N 3.28Å; E387-A389 PolarHBondContact O-N 3.08Å; E387-F390 PolarHBondContact O-N 3.36Å; E387-F390 VanDerWaalsContact O-N 3.1Å; E387-E391 WeakPolarHBondContact O-CG 3.45Å; E387-E391 PolarHBondContact O-N 2.96Å; E387-K424 IonicContact OE1-NZ 3.81Å; E387-K424 PolarHBondContact OE1-NZ 3.47Å; E387-K424 IonicContact OE2-NZ 3.06Å; E387-K424 PolarHBondContact OE2-NZ 3.06Å
388	E	96.8	Very high	92.8	Very high	73 Å²	73	58.1 Å²	58.1	34%	0.341	27%	0.271	S	S	.	.	H	α-helix	trans	-60.3	-37.8	179.6	-163.2	-160.6	153.5	0	0	112.4	K370 F386 F392	K370-E388 HydrophobicContact CD-CG 3.94Å; K370-E388 WeakPolarHBondContact CD-OE1 3.38Å; K370-E388 IonicContact NZ-OE1 2.95Å; K370-E388 PolarHBondContact NZ-OE1 3.31Å; F386-E388 PolarHBondContact O-N 3.06Å; E388-F392 PolarHBondContact O-N 3.28Å
389	A	98.4	Very high	94.1	Very high	0 Å²	0	55.8 Å²	55.8	0%	0	26%	0.263	C	S	.	.	H	α-helix	trans	-69.9	-41.8	176	0	0	0	0	0	111.6	I351 L372 Y385 F386 E387 F392 I393 I417	I351-A389 HydrophobicContact CD1-CB 4.36Å; L372-A389 HydrophobicContact CD1-CB 3.79Å; Y385-A389 WeakPolarHBondContact O-CB 3.06Å; Y385-A389 PolarHBondContact O-N 3.42Å; F386-A389 PolarHBondContact O-N 2.98Å; E387-A389 VanDerWaalsContact C-N 3.28Å; E387-A389 PolarHBondContact O-N 3.08Å; A389-F392 PolarHBondContact O-N 3.37Å; A389-I393 WeakPolarHBondContact O-CD1 3.23Å; A389-I393 VanDerWaalsContact O-CG1 3.23Å; A389-I393 WeakPolarHBondContact O-CG1 3.45Å; A389-I393 PolarHBondContact O-N 3.4Å; A389-I417 HydrophobicContact CB-CG2 3.63Å
390	F	97.6	Very high	95.1	Very high	3 Å²	3	49.7 Å²	49.7	1%	0.013	25%	0.253	C	S	.	.	H	α-helix	trans	-66.8	-44.2	-178.2	-60.3	-15.9	0	0	0	111.8	F386 E387 F392 I393 E394 A420 Y421 K424 H425 F457	F386-F390 HydrophobicContact CB-CD2 4.46Å; F386-F390 HydrophobicContact CB-CE1 4.33Å; F386-F390 HydrophobicContact CB-CE2 3.7Å; F386-F390 HydrophobicContact CB-CZ 3.63Å; F386-F390 HydrophobicContact CD2-CZ 4.22Å; F386-F390 HydrophobicContact CG-CE2 4.41Å; F386-F390 AromaticContact CG-CZ 3.92Å; F386-F390 HydrophobicContact CG-CZ 3.92Å; F386-F390 WeakPolarHBondContact O-CB 3.39Å; F386-F390 WeakPolarHBondContact O-CD1 3.29Å; F386-F390 WeakPolarHBondContact O-CD2 3.09Å; F386-F390 WeakPolarHBondContact O-CG 3.26Å; F386-F390 PolarHBondContact O-N 3.31Å; E387-F390 PolarHBondContact O-N 3.36Å; E387-F390 VanDerWaalsContact O-N 3.1Å; F390-F392 PolarHBondContact O-N 3.3Å; F390-I393 PolarHBondContact O-N 2.69Å; F390-I393 VanDerWaalsContact O-N 3.13Å; F390-E394 WeakPolarHBondContact O-CG 3.2Å; F390-E394 PolarHBondContact O-N 3.08Å; F390-A420 HydrophobicContact CE1-CB 4.14Å; F390-A420 HydrophobicContact CZ-CB 3.72Å; F390-Y421 HydrophobicContact CB-CD2 4.29Å; F390-Y421 AromaticContact CD1-CD2 3.68Å; F390-Y421 HydrophobicContact CD1-CD2 3.68Å; F390-Y421 HydrophobicContact CD1-CG 4.17Å; F390-Y421 HydrophobicContact CE1-CD2 4.38Å; F390-Y421 HydrophobicContact CE1-CG 4.48Å; F390-Y421 VanDerWaalsContact CE1-N 3.29Å; F390-Y421 HydrophobicContact CG-CD2 4.12Å; F390-K424 HydrophobicContact CD2-CB 4.43Å; F390-K424 HydrophobicContact CD2-CD 3.77Å; F390-K424 HydrophobicContact CD2-CG 4.44Å; F390-K424 HydrophobicContact CE2-CB 4.04Å; F390-K424 HydrophobicContact CE2-CD 3.75Å; F390-K424 HydrophobicContact CE2-CG 4.4Å; F390-H425 AromaticContact CG-CE1 3.88Å; F390-F457 HydrophobicContact CE2-CE1 4.34Å; F390-F457 AromaticContact CE2-CZ 3.85Å; F390-F457 HydrophobicContact CE2-CZ 3.85Å; F390-F457 HydrophobicContact CZ-CE1 4.31Å; F390-F457 HydrophobicContact CZ-CZ 4.23Å
391	E	96.6	Very high	95.7	Very high	119 Å²	119	52.3 Å²	52.3	56%	0.556	26%	0.263	S	S	*	.	H	α-helix	trans	-56	-43.1	175.1	-72.2	173.7	-177.9	0	0	111.2	E387 E394 E395	E387-E391 WeakPolarHBondContact O-CG 3.45Å; E387-E391 PolarHBondContact O-N 2.96Å; E391-E394 PolarHBondContact O-N 3.26Å; E391-E395 WeakPolarHBondContact O-CB 3.26Å; E391-E395 PolarHBondContact O-N 3.29Å
392	F	98.3	Very high	96	Very high	16 Å²	16	48.9 Å²	48.9	7%	0.07	25%	0.246	C	C	.	.	H	α-helix	trans	-71	-32.1	179	-159.6	-113.9	0	0	0	113.3	Y349 I351 N368 K370 E388 A389 F390 A396 L403	Y349-F392 HydrophobicContact CD1-CD1 4.34Å; Y349-F392 HydrophobicContact CD1-CD2 4.25Å; Y349-F392 AromaticContact CD1-CE1 3.84Å; Y349-F392 HydrophobicContact CD1-CE1 3.84Å; Y349-F392 AromaticContact CD1-CE2 3.73Å; Y349-F392 HydrophobicContact CD1-CE2 3.73Å; Y349-F392 AromaticContact CD1-CZ 3.53Å; Y349-F392 HydrophobicContact CD1-CZ 3.53Å; Y349-F392 HydrophobicContact CE1-CE2 4.08Å; Y349-F392 HydrophobicContact CE1-CZ 4.28Å; Y349-F392 HydrophobicContact CG-CE1 4.48Å; Y349-F392 HydrophobicContact CG-CZ 4.47Å; I351-F392 HydrophobicContact CD1-CB 4.45Å; I351-F392 HydrophobicContact CD1-CD1 3.93Å; I351-F392 HydrophobicContact CG1-CD1 3.52Å; I351-F392 HydrophobicContact CG1-CE1 4.02Å; N368-F392 HydrophobicContact CB-CE2 4.42Å; N368-F392 HydrophobicContact CB-CZ 4.02Å; N368-F392 WeakPolarHBondContact O-CZ 3.46Å; K370-F392 HydrophobicContact CB-CD1 3.67Å; K370-F392 HydrophobicContact CB-CD2 4.26Å; K370-F392 HydrophobicContact CB-CE1 3.55Å; K370-F392 HydrophobicContact CB-CE2 4.16Å; K370-F392 HydrophobicContact CB-CG 4.01Å; K370-F392 HydrophobicContact CB-CZ 3.79Å; K370-F392 HydrophobicContact CD-CB 3.82Å; K370-F392 HydrophobicContact CD-CD1 4.22Å; K370-F392 HydrophobicContact CD-CD2 4.28Å; K370-F392 HydrophobicContact CD-CG 3.87Å; E388-F392 PolarHBondContact O-N 3.28Å; A389-F392 PolarHBondContact O-N 3.37Å; F390-F392 PolarHBondContact O-N 3.3Å; F392-A396 PolarHBondContact O-N 2.97Å; F392-L403 HydrophobicContact CD1-CD1 3.84Å; F392-L403 HydrophobicContact CE1-CD1 4.35Å
393	I	97.8	Very high	96.1	Very high	0 Å²	0	48.9 Å²	48.9	0%	0	25%	0.246	C	C	.	.	H	α-helix	trans	-67.1	-44.8	172	-67.6	163.4	0	0	0	110.9	F327 L328 I351 A389 F390 A396 H397 L403 Y421	F327-I393 HydrophobicContact CE2-CG2 3.74Å; L328-I393 HydrophobicContact CD1-CD1 4.41Å; L328-I393 HydrophobicContact CD1-CG1 4.32Å; L328-I393 HydrophobicContact CD1-CG2 4.32Å; I351-I393 HydrophobicContact CD1-CD1 4.31Å; I351-I393 HydrophobicContact CD1-CG1 3.89Å; A389-I393 WeakPolarHBondContact O-CD1 3.23Å; A389-I393 VanDerWaalsContact O-CG1 3.23Å; A389-I393 WeakPolarHBondContact O-CG1 3.45Å; A389-I393 PolarHBondContact O-N 3.4Å; F390-I393 PolarHBondContact O-N 2.69Å; F390-I393 VanDerWaalsContact O-N 3.13Å; I393-A396 PolarHBondContact O-N 3.3Å; I393-H397 PolarHBondContact O-N 2.86Å; I393-L403 HydrophobicContact CB-CD1 4.42Å; I393-L403 HydrophobicContact CG1-CD1 3.92Å; I393-L403 HydrophobicContact CG1-CD2 4.16Å; I393-Y421 HydrophobicContact CB-CD2 4.2Å; I393-Y421 HydrophobicContact CB-CE2 3.95Å; I393-Y421 HydrophobicContact CD1-CD2 3.83Å; I393-Y421 HydrophobicContact CD1-CE2 4.42Å; I393-Y421 HydrophobicContact CD1-CG 3.95Å; I393-Y421 HydrophobicContact CG2-CD1 4.46Å; I393-Y421 HydrophobicContact CG2-CD2 3.97Å; I393-Y421 HydrophobicContact CG2-CE1 3.99Å; I393-Y421 HydrophobicContact CG2-CE2 3.44Å; I393-Y421 VanDerWaalsContact CG2-CE2 3.44Å; I393-Y421 HydrophobicContact CG2-CG 4.45Å; I393-Y421 VanDerWaalsContact CG2-CZ 3.46Å
394	E	95.3	Very high	96.3	Very high	43 Å²	43	46.1 Å²	46.1	20%	0.201	24%	0.235	C	C	.	.	H	α-helix	trans	-67.2	-36.5	177.4	-70.2	-57.8	115	0	0	112	F390 E391 H397 Q398 Y421 H425	F390-E394 WeakPolarHBondContact O-CG 3.2Å; F390-E394 PolarHBondContact O-N 3.08Å; E391-E394 PolarHBondContact O-N 3.26Å; E394-H397 WeakPolarHBondContact O-CB 3.13Å; E394-H397 PolarHBondContact O-N 3.36Å; E394-Q398 VanDerWaalsContact O-CB 3.27Å; E394-Q398 WeakPolarHBondContact O-CB 3.19Å; E394-Q398 PolarHBondContact O-N 3.14Å; E394-Y421 WeakPolarHBondContact OE1-CE2 3.3Å; E394-Y421 VanDerWaalsContact OE1-CZ 3.31Å; E394-Y421 PolarHBondContact OE1-OH 3.06Å; E394-H425 IonicContact OE1-CD2 2.88Å
395	E	95.6	Very high	96.4	Very high	93 Å²	93	40.8 Å²	40.8	44%	0.435	21%	0.211	S	C	.	.	H	α-helix	trans	-58.6	-49.7	173.5	-173.9	-175.4	171	0	0	111	Y349 E391 H397 Q398 C399	Y349-E395 HydrophobicContact CE1-CB 4.46Å; Y349-E395 HydrophobicContact CE1-CG 3.93Å; Y349-E395 PolarHBondContact OH-OE1 3.03Å; E391-E395 WeakPolarHBondContact O-CB 3.26Å; E391-E395 PolarHBondContact O-N 3.29Å; E395-H397 VanDerWaalsContact C-N 3.31Å; E395-H397 PolarHBondContact O-N 2.76Å; E395-Q398 PolarHBondContact O-N 3.45Å; E395-C399 PolarHBondContact O-N 3.3Å; E395-C399 PolarHBondContact O-SG 3.14Å; E395-C399 VanDerWaalsContact O-SG 3.36Å
396	A	95.9	Very high	96.4	Very high	0 Å²	0	39.5 Å²	39.5	0%	0	21%	0.206	C	C	.	.	H	α-helix	trans	-57.8	-45.2	176	0	0	0	0	0	112	Y349 F392 I393 C399 G400 K401 L403	Y349-A396 HydrophobicContact CD1-CB 4.07Å; Y349-A396 HydrophobicContact CD2-CB 3.38Å; Y349-A396 HydrophobicContact CE2-CB 3.98Å; Y349-A396 HydrophobicContact CG-CB 3.46Å; Y349-A396 VanDerWaalsContact CG-CB 3.46Å; F392-A396 PolarHBondContact O-N 2.97Å; I393-A396 PolarHBondContact O-N 3.3Å; A396-C399 PolarHBondContact O-N 3.39Å; A396-G400 PolarHBondContact O-N 2.52Å; A396-K401 CarbonylContact C-O 3.23Å; A396-K401 PolarHBondContact O-N 3.43Å; A396-K401 VanDerWaalsContact O-O 3.11Å; A396-L403 HydrophobicContact CB-CB 3.86Å; A396-L403 HydrophobicContact CB-CD1 3.96Å; A396-L403 HydrophobicContact CB-CG 4.49Å
397	H	93.6	Very high	96.3	Very high	48 Å²	48	39.4 Å²	39.4	22%	0.222	21%	0.205	C	C	.	.	H	α-helix	trans	-60.7	-45.6	177.5	-172.4	45.7	0	0	0	112	F327 I393 E394 E395 C399 G400	F327-H397 AromaticContact CD1-CE1 3.72Å; F327-H397 AromaticContact CD1-ND1 3.26Å; F327-H397 VanDerWaalsContact CD1-ND1 3.26Å; F327-H397 WeakPolarHBondContact CD1-ND1 3.42Å; F327-H397 HydrophobicContact CD2-CB 3.74Å; F327-H397 AromaticContact CD2-ND1 3.84Å; F327-H397 AromaticContact CE1-CE1 3.72Å; F327-H397 AromaticContact CE1-CG 3.87Å; F327-H397 AromaticContact CE1-ND1 3.44Å; F327-H397 WeakPolarHBondContact CE1-ND1 3.32Å; F327-H397 HydrophobicContact CE2-CB 3.57Å; F327-H397 AromaticContact CE2-CG 3.84Å; F327-H397 AromaticContact CE2-ND1 3.99Å; F327-H397 HydrophobicContact CG-CB 4.28Å; F327-H397 AromaticContact CG-ND1 3.47Å; F327-H397 WeakPolarHBondContact CG-ND1 3.43Å; F327-H397 HydrophobicContact CZ-CB 3.99Å; F327-H397 AromaticContact CZ-CG 3.75Å; F327-H397 AromaticContact CZ-ND1 3.8Å; I393-H397 PolarHBondContact O-N 2.86Å; E394-H397 WeakPolarHBondContact O-CB 3.13Å; E394-H397 PolarHBondContact O-N 3.36Å; E395-H397 VanDerWaalsContact C-N 3.31Å; E395-H397 PolarHBondContact O-N 2.76Å; H397-C399 VanDerWaalsContact C-N 3.28Å; H397-C399 PolarHBondContact O-N 3.34Å; H397-G400 PolarHBondContact O-N 2.72Å
398	Q	92.4	Very high	95.9	Very high	130 Å²	130	39.4 Å²	39.4	61%	0.607	21%	0.205	S	C	*	.	H	α-helix	trans	-69	-26.3	-177.7	-170.9	52	73.1	0	0	112.7	E394 E395 G400	E394-Q398 VanDerWaalsContact O-CB 3.27Å; E394-Q398 WeakPolarHBondContact O-CB 3.19Å; E394-Q398 PolarHBondContact O-N 3.14Å; E395-Q398 PolarHBondContact O-N 3.45Å; Q398-G400 VanDerWaalsContact C-N 3.3Å
399	C	93.4	Very high	95.1	Very high	73 Å²	73	37.6 Å²	37.6	49%	0.493	20%	0.203	S	C	.	.	T	Hydrogen-bonded Turn	trans	-83.2	0.3	171.1	-66.2	0	0	0	0	114	Y349 E395 A396 H397 K401	Y349-C399 HydrophobicContact CE2-CB 4.31Å; Y349-C399 PolarHBondContact OH-SG 3.44Å; E395-C399 PolarHBondContact O-N 3.3Å; E395-C399 PolarHBondContact O-SG 3.14Å; E395-C399 VanDerWaalsContact O-SG 3.36Å; A396-C399 PolarHBondContact O-N 3.39Å; H397-C399 VanDerWaalsContact C-N 3.28Å; H397-C399 PolarHBondContact O-N 3.34Å; C399-K401 HydrophobicContact CB-CG 4.24Å; C399-K401 PolarHBondContact O-N 2.96Å
400	G	92.1	Very high	94.7	Very high	55 Å²	55	37.6 Å²	37.6	57%	0.567	20%	0.203	S	C	*	.	T	Hydrogen-bonded Turn	trans	65	29.1	-176.6	0	0	0	0	0	113.2	N346 A396 H397 Q398	N346-G400 PolarHBondContact ND2-O 3.13Å; N346-G400 VanDerWaalsContact ND2-O 3.16Å; A396-G400 PolarHBondContact O-N 2.52Å; H397-G400 PolarHBondContact O-N 2.72Å; Q398-G400 VanDerWaalsContact C-N 3.3Å
401	K	96.6	Very high	94.1	Very high	85 Å²	85	38.6 Å²	38.6	37%	0.37	21%	0.209	S	C	.	.			trans	-109.6	149.8	180	-68.5	-66.2	178.5	177.6	0	111	N346 Y349 A396 C399	N346-K401 PolarHBondContact OD1-NZ 2.79Å; Y349-K401 HydrophobicContact CD2-CB 3.86Å; Y349-K401 HydrophobicContact CE2-CB 3.95Å; Y349-K401 HydrophobicContact CE2-CG 4.22Å; A396-K401 CarbonylContact C-O 3.23Å; A396-K401 PolarHBondContact O-N 3.43Å; A396-K401 VanDerWaalsContact O-O 3.11Å; C399-K401 HydrophobicContact CB-CG 4.24Å; C399-K401 PolarHBondContact O-N 2.96Å
402	G	97.2	Very high	93.8	Very high	3 Å²	3	33 Å²	33	3%	0.031	18%	0.184	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-72.5	148.3	167.5	0	0	0	0	0	111	F327 N346 I347 G348 Y349	F327-G402 CarbonylContact O-C 3.48Å; F327-G402 WeakPolarHBondContact O-CA 3.4Å; N346-G402 PolarHBondContact O-N 2.77Å; I347-G402 CarbonylContact C-O 3.59Å; I347-G402 VanDerWaalsContact CA-O 3.32Å; I347-G402 WeakPolarHBondContact CA-O 3.34Å; G348-G402 PolarHBondContact N-O 3.37Å; Y349-G402 PolarHBondContact N-O 2.9Å
403	L	98.7	Very high	93.8	Very high	0 Å²	0	32.8 Å²	32.8	0%	0	18%	0.182	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-118.4	127	170.9	-173.3	146	0	0	0	110.2	F327 L328 F329 Y349 I351 F392 I393 A396 I405	F327-L403 PolarHBondContact O-N 2.98Å; L328-L403 HydrophobicContact CD1-CB 4.41Å; L328-L403 HydrophobicContact CD1-CD2 3.62Å; F329-L403 PolarHBondContact N-O 3.38Å; Y349-L403 WeakPolarHBondContact O-CA 3.36Å; I351-L403 HydrophobicContact CD1-CD1 3.98Å; I351-L403 HydrophobicContact CD1-CD2 4.04Å; I351-L403 HydrophobicContact CG1-CD1 4.09Å; I351-L403 HydrophobicContact CG1-CD2 4.14Å; F392-L403 HydrophobicContact CD1-CD1 3.84Å; F392-L403 HydrophobicContact CE1-CD1 4.35Å; I393-L403 HydrophobicContact CB-CD1 4.42Å; I393-L403 HydrophobicContact CG1-CD1 3.92Å; I393-L403 HydrophobicContact CG1-CD2 4.16Å; A396-L403 HydrophobicContact CB-CB 3.86Å; A396-L403 HydrophobicContact CB-CD1 3.96Å; A396-L403 HydrophobicContact CB-CG 4.49Å; L403-I405 HydrophobicContact CD2-CB 3.95Å; L403-I405 HydrophobicContact CD2-CG2 4.44Å
404	L	98.8	Very high	93.8	Very high	0 Å²	0	32.8 Å²	32.8	0%	0	18%	0.182	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-92.3	124.9	165.3	169.4	64.6	0	0	0	109.4	L321 A336 M342 I347 Y349 V350 I351 H406	L321-L404 HydrophobicContact CD1-CD1 3.38Å; A336-L404 HydrophobicContact CB-CD2 4Å; M342-L404 HydrophobicContact CE-CD2 3.96Å; M342-L404 HydrophobicContact CG-CD2 4.37Å; M342-L404 HydrophobicContact SD-CD2 4.09Å; I347-L404 HydrophobicContact CD1-CB 4Å; I347-L404 HydrophobicContact CG2-CB 4.07Å; Y349-L404 PolarHBondContact O-N 3.27Å; V350-L404 CarbonylContact C-O 3.56Å; V350-L404 VanDerWaalsContact CA-O 3.28Å; V350-L404 WeakPolarHBondContact CA-O 3.26Å; V350-L404 HydrophobicContact CG1-CD2 4.36Å; I351-L404 PolarHBondContact N-O 2.85Å; L404-H406 HydrophobicContact CD1-CB 4.38Å; L404-H406 HydrophobicContact CG-CB 4.48Å
405	I	98.9	Very high	93.9	Very high	0 Å²	0	30.8 Å²	30.8	0%	0	17%	0.173	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-112.2	125.5	164	-176.7	165.3	0	0	0	109.6	L328 F329 L330 G331 I351 V353 L403 I417 V418	L328-I405 HydrophobicContact CD1-CG2 4.1Å; F329-I405 WeakPolarHBondContact O-CG2 3.06Å; F329-I405 PolarHBondContact O-N 2.9Å; L330-I405 WeakPolarHBondContact CA-O 3.25Å; L330-I405 HydrophobicContact CD1-CG2 4.39Å; G331-I405 PolarHBondContact N-O 3.1Å; I351-I405 HydrophobicContact CB-CB 4.07Å; I351-I405 HydrophobicContact CB-CD1 4.11Å; I351-I405 HydrophobicContact CB-CG1 3.82Å; I351-I405 HydrophobicContact CD1-CD1 4.26Å; I351-I405 HydrophobicContact CG2-CD1 3.81Å; I351-I405 HydrophobicContact CG2-CG1 3.83Å; I351-I405 WeakPolarHBondContact O-CA 3.22Å; V353-I405 HydrophobicContact CG2-CD1 4Å; V353-I405 HydrophobicContact CG2-CG1 3.91Å; L403-I405 HydrophobicContact CD2-CB 3.95Å; L403-I405 HydrophobicContact CD2-CG2 4.44Å; I405-I417 HydrophobicContact CD1-CB 3.6Å; I405-I417 HydrophobicContact CD1-CG1 4.24Å; I405-I417 HydrophobicContact CD1-CG2 3.42Å; I405-I417 VanDerWaalsContact CD1-CG2 3.42Å; I405-V418 HydrophobicContact CG2-CG2 3.44Å; I405-V418 VanDerWaalsContact CG2-CG2 3.44Å
406	H	98.5	Very high	94.1	Very high	2 Å²	2	26.3 Å²	26.3	1%	0.009	15%	0.152	C	C	.	.	E	Extended strand (participates in β ladder)	trans	-137.2	160.9	-178.5	79.9	96.8	0	0	0	111.9	G331 I351 V353 L404	G331-H406 WeakPolarHBondContact O-CA 3.31Å; G331-H406 WeakPolarHBondContact O-CB 3.49Å; I351-H406 PolarHBondContact O-CD2 3.46Å; I351-H406 PolarHBondContact O-N 3.25Å; V353-H406 PolarHBondContact N-O 3.1Å; L404-H406 HydrophobicContact CD1-CB 4.38Å; L404-H406 HydrophobicContact CG-CB 4.48Å
407	C	95.1	Very high	94.2	Very high	3 Å²	3	26.3 Å²	26.3	2%	0.02	15%	0.152	C	C	.	.			trans	-125.8	-129.8	162.9	60.4	0	0	0	0	108	V353 T354 G410 R413 S414	V353-C407 HydrophobicContact CB-CB 4.28Å; T354-C407 HydrophobicContact CG2-CB 4.06Å; C407-G410 PolarHBondContact SG-N 2.66Å; C407-G410 VanDerWaalsContact SG-N 3.4Å; C407-R413 HydrophobicContact CB-CB 3.94Å; C407-S414 PolarHBondContact SG-OG 2.67Å
408	Q	86.6	Confident	94.4	Very high	81 Å²	81	24 Å²	24	38%	0.379	14%	0.142	S	C	.	.	S	Bend	trans	-85.3	-72.4	171.4	-167.2	162.6	20.1	0	0	110.7	N332 E333 L357	N332-Q408 CarbonylContact C-O 3.31Å; N332-Q408 VanDerWaalsContact CA-O 3.26Å; N332-Q408 WeakPolarHBondContact CA-O 3.13Å; N332-Q408 VanDerWaalsContact CB-O 3.23Å; N332-Q408 WeakPolarHBondContact CB-O 3.41Å; E333-Q408 PolarHBondContact N-O 3.03Å; E333-Q408 VanDerWaalsContact OE1-CG 3.3Å; E333-Q408 WeakPolarHBondContact OE1-CG 3.42Å; E333-Q408 PolarHBondContact OE1-NE2 2.8Å; L357-Q408 HydrophobicContact CD1-CB 4.4Å
409	A	80.3	Confident	94.7	Very high	36 Å²	36	17.9 Å²	17.9	30%	0.298	11%	0.113	S	C	.	.	S	Bend	trans	-86	-9.6	-179.8	0	0	0	0	0	114.9	I316 V411 R441	I316-A409 HydrophobicContact CG2-CB 4.13Å; A409-V411 VanDerWaalsContact C-N 3.28Å; A409-V411 HydrophobicContact CB-CB 4.23Å; A409-V411 HydrophobicContact CB-CG2 3.7Å; A409-V411 PolarHBondContact O-N 3.37Å; A409-R441 PolarHBondContact O-NH2 2.73Å
410	G	90.3	Very high	94.9	Very high	0 Å²	0	14.4 Å²	14.4	0%	0	9%	0.089	C	C	.	.	S	Bend	trans	67.7	28.8	-172.2	0	0	0	0	0	113.6	G331 C407 R441	G331-G410 WeakPolarHBondContact O-CA 3.41Å; C407-G410 PolarHBondContact SG-N 2.66Å; C407-G410 VanDerWaalsContact SG-N 3.4Å; G410-R441 PolarHBondContact O-NE 2.96Å
411	V	84.6	Confident	95.2	Very high	23 Å²	23	11.8 Å²	11.8	14%	0.139	6%	0.062	C	C	.	.	S	Bend	trans	-104.8	-50.9	-172.5	169	0	0	0	0	112.5	I316 A409 A415 I443 I444 S445	I316-V411 HydrophobicContact CG2-CG2 4.12Å; A409-V411 VanDerWaalsContact C-N 3.28Å; A409-V411 HydrophobicContact CB-CB 4.23Å; A409-V411 HydrophobicContact CB-CG2 3.7Å; A409-V411 PolarHBondContact O-N 3.37Å; V411-A415 WeakPolarHBondContact O-CB 3.2Å; V411-I443 WeakPolarHBondContact CG1-O 3.45Å; V411-I443 HydrophobicContact CG2-CD1 3.74Å; V411-I443 HydrophobicContact CG2-CG1 4.24Å; V411-I444 WeakPolarHBondContact O-CA 3.42Å; V411-S445 CarbonylContact O-C 3.56Å; V411-S445 PolarHBondContact O-N 3.12Å
412	S	89.6	Confident	95.2	Very high	2 Å²	2	7.7 Å²	7.7	1%	0.014	5%	0.045	C	C	.	.	S	Bend	trans	-113.7	-70.1	-166.5	172.3	0	0	0	0	113.2	D376 A415 T416 N447 F450	D376-S412 WeakPolarHBondContact OD1-CB 3.15Å; D376-S412 PolarHBondContact OD1-OG 3.45Å; D376-S412 WeakPolarHBondContact OD2-CB 3.47Å; D376-S412 PolarHBondContact OD2-OG 3.36Å; S412-A415 PolarHBondContact O-N 2.73Å; S412-T416 WeakPolarHBondContact O-CB 3.38Å; S412-T416 PolarHBondContact O-N 3.37Å; S412-T416 PolarHBondContact O-OG1 2.94Å; S412-N447 PolarHBondContact OG-N 2.83Å; S412-N447 VanDerWaalsContact OG-N 3.15Å; S412-F450 WeakPolarHBondContact OG-CD2 3.4Å; S412-F450 WeakPolarHBondContact OG-CE2 3.35Å
413	R	98	Very high	95.1	Very high	12 Å²	12	7.6 Å²	7.6	5%	0.045	4%	0.043	C	C	.	.	H	α-helix	trans	-60.4	-56.3	-174.5	-70.4	168.9	-75.8	-179.7	-6	113.9	V353 A374 D376 L382 C407 A415 T416 I417 F450	V353-R413 HydrophobicContact CB-CB 4.2Å; V353-R413 HydrophobicContact CG1-CB 3.79Å; V353-R413 WeakPolarHBondContact O-CD 3.47Å; V353-R413 PolarHBondContact O-NH1 3.02Å; A374-R413 WeakPolarHBondContact O-CD 3.44Å; A374-R413 PolarHBondContact O-NH1 3.19Å; D376-R413 HydrophobicContact CB-CG 4.11Å; L382-R413 HydrophobicContact CD1-CB 4.39Å; L382-R413 HydrophobicContact CD1-CG 4.42Å; C407-R413 HydrophobicContact CB-CB 3.94Å; R413-A415 VanDerWaalsContact C-N 3.34Å; R413-A415 PolarHBondContact O-N 3.19Å; R413-T416 WeakPolarHBondContact O-CB 3.46Å; R413-T416 PolarHBondContact O-N 2.82Å; R413-I417 PolarHBondContact O-N 3.3Å; R413-F450 HydrophobicContact CB-CE2 4.42Å; R413-F450 HydrophobicContact CG-CE2 3.6Å; R413-F450 HydrophobicContact CG-CZ 3.99Å
414	S	98.4	Very high	94.9	Very high	0 Å²	0	7.7 Å²	7.7	0%	0	4%	0.043	C	C	.	.	H	α-helix	trans	-64.8	-39	-179.8	49.1	0	0	0	0	111.9	L330 C407 T416 I417 V418	L330-S414 VanDerWaalsContact CD1-OG 3.25Å; L330-S414 WeakPolarHBondContact CD1-OG 3.42Å; C407-S414 PolarHBondContact SG-OG 2.67Å; S414-T416 VanDerWaalsContact C-N 3.31Å; S414-T416 PolarHBondContact O-N 3.12Å; S414-I417 PolarHBondContact O-N 2.95Å; S414-V418 WeakPolarHBondContact O-CG2 3.34Å; S414-V418 PolarHBondContact O-N 2.94Å; S414-V418 VanDerWaalsContact O-N 3.13Å
415	A	97.9	Very high	94.5	Very high	0 Å²	0	8 Å²	8	0%	0	5%	0.045	C	C	.	.	H	α-helix	trans	-60.8	-39.6	174.6	0	0	0	0	0	112.2	L330 V411 S412 R413 I417 V418 I419 I444 P446	L330-A415 HydrophobicContact CD2-CB 4.15Å; V411-A415 WeakPolarHBondContact O-CB 3.2Å; S412-A415 PolarHBondContact O-N 2.73Å; R413-A415 VanDerWaalsContact C-N 3.34Å; R413-A415 PolarHBondContact O-N 3.19Å; A415-I417 PolarHBondContact O-N 3Å; A415-V418 PolarHBondContact O-N 3.39Å; A415-I419 WeakPolarHBondContact O-CD1 3.21Å; A415-I419 VanDerWaalsContact O-CG1 3.24Å; A415-I419 WeakPolarHBondContact O-CG1 3.33Å; A415-I419 PolarHBondContact O-N 3.12Å; A415-I444 HydrophobicContact CB-CB 3.94Å; A415-I444 HydrophobicContact CB-CG2 3.78Å; A415-P446 HydrophobicContact CB-CG 4.32Å
416	T	98.4	Very high	93.9	Very high	0 Å²	0	8.1 Å²	8.1	0%	0	5%	0.046	C	C	.	.	H	α-helix	trans	-58.6	-47.3	177	-58	0	0	0	0	111.5	L382 F386 S412 R413 S414 V418 I419 A420 F450 L454	L382-T416 HydrophobicContact CD1-CG2 3.9Å; F386-T416 HydrophobicContact CE1-CG2 4.39Å; F386-T416 HydrophobicContact CZ-CG2 4.33Å; S412-T416 WeakPolarHBondContact O-CB 3.38Å; S412-T416 PolarHBondContact O-N 3.37Å; S412-T416 PolarHBondContact O-OG1 2.94Å; R413-T416 WeakPolarHBondContact O-CB 3.46Å; R413-T416 PolarHBondContact O-N 2.82Å; S414-T416 VanDerWaalsContact C-N 3.31Å; S414-T416 PolarHBondContact O-N 3.12Å; T416-V418 VanDerWaalsContact C-N 3.35Å; T416-V418 PolarHBondContact O-N 2.96Å; T416-I419 PolarHBondContact O-N 2.98Å; T416-A420 WeakPolarHBondContact O-CB 3.03Å; T416-A420 PolarHBondContact O-N 2.96Å; T416-F450 HydrophobicContact CG2-CB 3.83Å; T416-F450 HydrophobicContact CG2-CG 4.28Å; T416-F450 WeakPolarHBondContact OG1-CB 3.18Å; T416-L454 HydrophobicContact CG2-CD1 4.09Å; T416-L454 HydrophobicContact CG2-CD2 4.13Å; T416-L454 HydrophobicContact CG2-CG 4.01Å
417	I	98.8	Very high	93.2	Very high	0 Å²	0	16.7 Å²	16.7	0%	0	8%	0.078	C	C	.	.	H	α-helix	trans	-62.7	-43.2	178.5	-60.2	-65.5	0	0	0	110.9	V353 L372 L382 F386 A389 I405 R413 S414 A415 A420 Y421	V353-I417 HydrophobicContact CG2-CG1 4.41Å; L372-I417 HydrophobicContact CD1-CD1 4.32Å; L372-I417 HydrophobicContact CD1-CG1 4.42Å; L382-I417 HydrophobicContact CD2-CD1 4.47Å; F386-I417 HydrophobicContact CD1-CD1 3.7Å; F386-I417 HydrophobicContact CE1-CD1 3.79Å; A389-I417 HydrophobicContact CB-CG2 3.63Å; I405-I417 HydrophobicContact CD1-CB 3.6Å; I405-I417 HydrophobicContact CD1-CG1 4.24Å; I405-I417 HydrophobicContact CD1-CG2 3.42Å; I405-I417 VanDerWaalsContact CD1-CG2 3.42Å; R413-I417 PolarHBondContact O-N 3.3Å; S414-I417 PolarHBondContact O-N 2.95Å; A415-I417 PolarHBondContact O-N 3Å; I417-A420 PolarHBondContact O-N 2.83Å; I417-Y421 WeakPolarHBondContact O-CB 3.38Å; I417-Y421 PolarHBondContact O-N 3.38Å
418	V	98.7	Very high	92.8	Very high	0 Å²	0	17.2 Å²	17.2	0%	0	8%	0.08	C	C	.	.	H	α-helix	trans	-61.8	-45.2	177.7	172.9	0	0	0	0	111.6	I324 L328 L330 I405 S414 A415 T416 Y421 L422 V437	I324-V418 HydrophobicContact CB-CG1 4.33Å; I324-V418 HydrophobicContact CG1-CG1 4.1Å; I324-V418 HydrophobicContact CG2-CG1 3.73Å; L328-V418 HydrophobicContact CD2-CG1 4.37Å; L330-V418 HydrophobicContact CD1-CG2 4.31Å; I405-V418 HydrophobicContact CG2-CG2 3.44Å; I405-V418 VanDerWaalsContact CG2-CG2 3.44Å; S414-V418 WeakPolarHBondContact O-CG2 3.34Å; S414-V418 PolarHBondContact O-N 2.94Å; S414-V418 VanDerWaalsContact O-N 3.13Å; A415-V418 PolarHBondContact O-N 3.39Å; T416-V418 VanDerWaalsContact C-N 3.35Å; T416-V418 PolarHBondContact O-N 2.96Å; V418-Y421 PolarHBondContact O-N 3Å; V418-L422 HydrophobicContact CG1-CD1 4.35Å; V418-L422 WeakPolarHBondContact O-CG 3.27Å; V418-L422 PolarHBondContact O-N 3.16Å; V418-V437 HydrophobicContact CG1-CG1 4.35Å; V418-V437 HydrophobicContact CG1-CG2 3.78Å
419	I	98.4	Very high	92.9	Very high	0 Å²	0	15.9 Å²	15.9	0%	0	8%	0.078	C	C	.	.	H	α-helix	trans	-61.4	-46.9	178.2	-68.1	162.9	0	0	0	110	A415 T416 Y421 L422 M423 A433 Y434 V437 I444 P446 L454	A415-I419 WeakPolarHBondContact O-CD1 3.21Å; A415-I419 VanDerWaalsContact O-CG1 3.24Å; A415-I419 WeakPolarHBondContact O-CG1 3.33Å; A415-I419 PolarHBondContact O-N 3.12Å; T416-I419 PolarHBondContact O-N 2.98Å; I419-Y421 VanDerWaalsContact C-N 3.32Å; I419-Y421 PolarHBondContact O-N 2.79Å; I419-L422 PolarHBondContact O-N 3.49Å; I419-M423 HydrophobicContact CG2-SD 3.94Å; I419-M423 VanDerWaalsContact O-CG 3.27Å; I419-M423 WeakPolarHBondContact O-CG 3.21Å; I419-M423 PolarHBondContact O-N 3.34Å; I419-A433 HydrophobicContact CG2-CB 3.9Å; I419-Y434 HydrophobicContact CD1-CD2 3.83Å; I419-Y434 HydrophobicContact CD1-CG 4.43Å; I419-V437 HydrophobicContact CG1-CB 4.29Å; I419-V437 HydrophobicContact CG1-CG2 3.93Å; I419-I444 HydrophobicContact CD1-CD1 4.35Å; I419-P446 HydrophobicContact CD1-CG 4.02Å; I419-L454 HydrophobicContact CB-CD1 4.26Å; I419-L454 HydrophobicContact CB-CD2 4.38Å; I419-L454 HydrophobicContact CD1-CD1 4.39Å; I419-L454 HydrophobicContact CG2-CD1 3.9Å; I419-L454 HydrophobicContact CG2-CD2 4.05Å
420	A	98.2	Very high	93.5	Very high	0 Å²	0	14.5 Å²	14.5	0%	0	7%	0.065	C	C	.	.	H	α-helix	trans	-61.4	-40.5	177.5	0	0	0	0	0	112.2	F386 F390 T416 I417 M423 K424 L454 F457	F386-A420 HydrophobicContact CD1-CB 4.23Å; F386-A420 HydrophobicContact CD2-CB 3.82Å; F386-A420 HydrophobicContact CE1-CB 3.94Å; F386-A420 HydrophobicContact CE2-CB 3.49Å; F386-A420 VanDerWaalsContact CE2-CB 3.49Å; F386-A420 HydrophobicContact CG-CB 4.18Å; F386-A420 HydrophobicContact CZ-CB 3.56Å; F390-A420 HydrophobicContact CE1-CB 4.14Å; F390-A420 HydrophobicContact CZ-CB 3.72Å; T416-A420 WeakPolarHBondContact O-CB 3.03Å; T416-A420 PolarHBondContact O-N 2.96Å; I417-A420 PolarHBondContact O-N 2.83Å; A420-M423 PolarHBondContact O-N 3.42Å; A420-K424 PolarHBondContact O-N 3.48Å; A420-L454 HydrophobicContact CB-CD2 3.71Å; A420-F457 HydrophobicContact CB-CD1 4.14Å; A420-F457 HydrophobicContact CB-CE1 4.08Å
421	Y	97.8	Very high	93.2	Very high	0 Å²	0	16.2 Å²	16.2	0%	0	8%	0.076	C	C	.	.	H	α-helix	trans	-60.7	-48.5	176.9	171.8	-98.2	0	0	0	111.3	L325 F327 L328 F390 I393 E394 I417 V418 I419 M423 K424 H425	L325-Y421 HydrophobicContact CD1-CE1 3.83Å; F327-Y421 WeakPolarHBondContact CZ-OH 3.38Å; L328-Y421 HydrophobicContact CD2-CD1 3.82Å; L328-Y421 HydrophobicContact CD2-CE1 4.03Å; F390-Y421 HydrophobicContact CB-CD2 4.29Å; F390-Y421 AromaticContact CD1-CD2 3.68Å; F390-Y421 HydrophobicContact CD1-CD2 3.68Å; F390-Y421 HydrophobicContact CD1-CG 4.17Å; F390-Y421 HydrophobicContact CE1-CD2 4.38Å; F390-Y421 HydrophobicContact CE1-CG 4.48Å; F390-Y421 VanDerWaalsContact CE1-N 3.29Å; F390-Y421 HydrophobicContact CG-CD2 4.12Å; I393-Y421 HydrophobicContact CB-CD2 4.2Å; I393-Y421 HydrophobicContact CB-CE2 3.95Å; I393-Y421 HydrophobicContact CD1-CD2 3.83Å; I393-Y421 HydrophobicContact CD1-CE2 4.42Å; I393-Y421 HydrophobicContact CD1-CG 3.95Å; I393-Y421 HydrophobicContact CG2-CD1 4.46Å; I393-Y421 HydrophobicContact CG2-CD2 3.97Å; I393-Y421 HydrophobicContact CG2-CE1 3.99Å; I393-Y421 HydrophobicContact CG2-CE2 3.44Å; I393-Y421 VanDerWaalsContact CG2-CE2 3.44Å; I393-Y421 HydrophobicContact CG2-CG 4.45Å; I393-Y421 VanDerWaalsContact CG2-CZ 3.46Å; E394-Y421 WeakPolarHBondContact OE1-CE2 3.3Å; E394-Y421 VanDerWaalsContact OE1-CZ 3.31Å; E394-Y421 PolarHBondContact OE1-OH 3.06Å; I417-Y421 WeakPolarHBondContact O-CB 3.38Å; I417-Y421 PolarHBondContact O-N 3.38Å; V418-Y421 PolarHBondContact O-N 3Å; I419-Y421 VanDerWaalsContact C-N 3.32Å; I419-Y421 PolarHBondContact O-N 2.79Å; Y421-M423 VanDerWaalsContact C-N 3.32Å; Y421-M423 PolarHBondContact O-N 2.82Å; Y421-K424 PolarHBondContact O-N 3.36Å; Y421-H425 AromaticContact CD2-CE1 3.65Å; Y421-H425 AromaticContact CD2-ND1 3.32Å; Y421-H425 VanDerWaalsContact CD2-ND1 3.32Å; Y421-H425 WeakPolarHBondContact CD2-ND1 3.17Å; Y421-H425 HydrophobicContact CE2-CB 4.33Å; Y421-H425 AromaticContact CE2-CE1 3.6Å; Y421-H425 AromaticContact CE2-CG 3.62Å; Y421-H425 AromaticContact CE2-ND1 3.33Å; Y421-H425 VanDerWaalsContact CE2-ND1 3.33Å; Y421-H425 WeakPolarHBondContact CE2-ND1 3.29Å; Y421-H425 AromaticContact CZ-CG 3.98Å; Y421-H425 PolarHBondContact O-N 3.33Å; Y421-H425 PolarHBondContact O-ND1 3.3Å
422	L	96.1	Very high	93.2	Very high	0 Å²	0	17.4 Å²	17.4	0%	0	8%	0.082	C	C	.	.	H	α-helix	trans	-59.4	-43.2	176.2	-69.1	173.6	0	0	0	111.1	I324 L325 V418 I419 K424 T426 A433 F436 V437	I324-L422 HydrophobicContact CG2-CD1 4.18Å; L325-L422 HydrophobicContact CD1-CD2 4.13Å; L325-L422 HydrophobicContact CD2-CD2 4.3Å; L325-L422 HydrophobicContact CG-CD2 4.37Å; V418-L422 HydrophobicContact CG1-CD1 4.35Å; V418-L422 WeakPolarHBondContact O-CG 3.27Å; V418-L422 PolarHBondContact O-N 3.16Å; I419-L422 PolarHBondContact O-N 3.49Å; L422-K424 VanDerWaalsContact C-N 3.35Å; L422-K424 PolarHBondContact O-N 3.34Å; L422-T426 VanDerWaalsContact O-CB 3.3Å; L422-T426 WeakPolarHBondContact O-CB 3.27Å; L422-T426 PolarHBondContact O-N 2.7Å; L422-T426 PolarHBondContact O-OG1 3.48Å; L422-A433 HydrophobicContact CB-CB 4.05Å; L422-F436 HydrophobicContact CD1-CD1 3.58Å; L422-F436 HydrophobicContact CD1-CE1 4.04Å; L422-V437 HydrophobicContact CD1-CG2 3.53Å
423	M	95.1	Very high	93.3	Very high	0 Å²	0	17.3 Å²	17.3	0%	0	8%	0.081	C	C	.	.	H	α-helix	trans	-61	-40.5	176.5	-67	162.8	57.3	0	0	112.6	I419 A420 Y421 M430 A433 L454 F457 E458 L461 R468	I419-M423 HydrophobicContact CG2-SD 3.94Å; I419-M423 VanDerWaalsContact O-CG 3.27Å; I419-M423 WeakPolarHBondContact O-CG 3.21Å; I419-M423 PolarHBondContact O-N 3.34Å; A420-M423 PolarHBondContact O-N 3.42Å; Y421-M423 VanDerWaalsContact C-N 3.32Å; Y421-M423 PolarHBondContact O-N 2.82Å; M423-M430 HydrophobicContact CE-CB 3.87Å; M423-M430 HydrophobicContact CE-CG 4.34Å; M423-M430 HydrophobicContact SD-CB 3.85Å; M423-M430 HydrophobicContact SD-CG 3.99Å; M423-A433 HydrophobicContact CG-CB 3.81Å; M423-L454 WeakPolarHBondContact CE-O 3.48Å; M423-L454 HydrophobicContact SD-CD2 4.14Å; M423-F457 HydrophobicContact CE-CD1 3.87Å; M423-E458 HydrophobicContact CE-CB 3.55Å; M423-E458 HydrophobicContact CE-CG 4.33Å; M423-L461 HydrophobicContact CB-CD1 3.91Å; M423-L461 HydrophobicContact CE-CD1 4.25Å; M423-R468 PolarHBondContact O-NH1 3.36Å
424	K	94.1	Very high	93	Very high	2 Å²	2	17.1 Å²	17.1	1%	0.009	8%	0.08	C	C	.	.	H	α-helix	trans	-76.7	-35.3	-178	-179.8	152.3	167.4	173.5	0	113.2	E387 F390 A420 Y421 L422 F457 L461 T466 P467 I469	E387-K424 IonicContact OE1-NZ 3.81Å; E387-K424 PolarHBondContact OE1-NZ 3.47Å; E387-K424 IonicContact OE2-NZ 3.06Å; E387-K424 PolarHBondContact OE2-NZ 3.06Å; F390-K424 HydrophobicContact CD2-CB 4.43Å; F390-K424 HydrophobicContact CD2-CD 3.77Å; F390-K424 HydrophobicContact CD2-CG 4.44Å; F390-K424 HydrophobicContact CE2-CB 4.04Å; F390-K424 HydrophobicContact CE2-CD 3.75Å; F390-K424 HydrophobicContact CE2-CG 4.4Å; A420-K424 PolarHBondContact O-N 3.48Å; Y421-K424 PolarHBondContact O-N 3.36Å; L422-K424 VanDerWaalsContact C-N 3.35Å; L422-K424 PolarHBondContact O-N 3.34Å; K424-F457 HydrophobicContact CB-CE1 4.23Å; K424-F457 HydrophobicContact CB-CZ 4.08Å; K424-F457 HydrophobicContact CD-CZ 4.02Å; K424-L461 HydrophobicContact CB-CD2 4.29Å; K424-L461 HydrophobicContact CD-CD2 4.31Å; K424-L461 HydrophobicContact CG-CD2 4.22Å; K424-T466 HydrophobicContact CD-CG2 4.07Å; K424-P467 VanDerWaalsContact CE-O 3.24Å; K424-P467 WeakPolarHBondContact CE-O 3.49Å; K424-I469 PolarHBondContact O-N 2.69Å
425	H	91.9	Very high	92.4	Very high	6 Å²	6	21.5 Å²	21.5	3%	0.028	10%	0.099	C	C	.	.	H	α-helix	trans	-99.1	-2.9	-173.3	-62.8	78.6	0	0	0	114.1	F390 E394 Y421 I469 L474	F390-H425 AromaticContact CG-CE1 3.88Å; E394-H425 IonicContact OE1-CD2 2.88Å; Y421-H425 AromaticContact CD2-CE1 3.65Å; Y421-H425 AromaticContact CD2-ND1 3.32Å; Y421-H425 VanDerWaalsContact CD2-ND1 3.32Å; Y421-H425 WeakPolarHBondContact CD2-ND1 3.17Å; Y421-H425 HydrophobicContact CE2-CB 4.33Å; Y421-H425 AromaticContact CE2-CE1 3.6Å; Y421-H425 AromaticContact CE2-CG 3.62Å; Y421-H425 AromaticContact CE2-ND1 3.33Å; Y421-H425 VanDerWaalsContact CE2-ND1 3.33Å; Y421-H425 WeakPolarHBondContact CE2-ND1 3.29Å; Y421-H425 AromaticContact CZ-CG 3.98Å; Y421-H425 PolarHBondContact O-N 3.33Å; Y421-H425 PolarHBondContact O-ND1 3.3Å; H425-I469 WeakPolarHBondContact CA-O 3.41Å; H425-L474 HydrophobicContact CB-CD1 3.76Å
426	T	85.8	Confident	92	Very high	3 Å²	3	23.6 Å²	23.6	2%	0.018	11%	0.108	C	C	.	.	S	Bend	trans	-132.4	175.1	171.9	77.2	0	0	0	0	109.6	L422 M428 R468 L474	L422-T426 VanDerWaalsContact O-CB 3.3Å; L422-T426 WeakPolarHBondContact O-CB 3.27Å; L422-T426 PolarHBondContact O-N 2.7Å; L422-T426 PolarHBondContact O-OG1 3.48Å; T426-M428 PolarHBondContact O-N 2.87Å; T426-M428 WeakPolarHBondContact OG1-CB 3.44Å; T426-M428 VanDerWaalsContact OG1-CG 3.27Å; T426-M428 WeakPolarHBondContact OG1-CG 3.39Å; T426-M428 PolarHBondContact OG1-N 3.28Å; T426-M428 VanDerWaalsContact OG1-N 3.11Å; T426-R468 PolarHBondContact O-NH1 2.82Å; T426-L474 HydrophobicContact CG2-CD1 4.44Å
427	R	82.4	Confident	91.9	Very high	183 Å²	183	23.6 Å²	23.6	69%	0.691	11%	0.108	S	C	*	.	S	Bend	trans	-85.4	15	169.9	-70.2	-170.2	172.4	164.1	1.9	114.6	L470 E478	R427-L470 HydrophobicContact CG-CD1 3.98Å; R427-L470 HydrophobicContact CG-CD2 3.72Å; R427-L470 VanDerWaalsContact NE-CD1 3.27Å; R427-E478 PolarHBondContact N-OE1 3.39Å
428	M	86.9	Confident	91.4	Very high	14 Å²	14	25.4 Å²	25.4	7%	0.069	12%	0.116	C	C	.	.			trans	-64.4	139.6	178.1	-71.1	179.4	170.9	0	0	111.9	T426 D432 A433 F436 V477 V481	T426-M428 PolarHBondContact O-N 2.87Å; T426-M428 WeakPolarHBondContact OG1-CB 3.44Å; T426-M428 VanDerWaalsContact OG1-CG 3.27Å; T426-M428 WeakPolarHBondContact OG1-CG 3.39Å; T426-M428 PolarHBondContact OG1-N 3.28Å; T426-M428 VanDerWaalsContact OG1-N 3.11Å; M428-D432 HydrophobicContact CB-CB 4.35Å; M428-D432 HydrophobicContact CG-CB 4.48Å; M428-A433 HydrophobicContact CB-CB 4.08Å; M428-A433 HydrophobicContact SD-CB 4.41Å; M428-F436 HydrophobicContact CE-CB 4.44Å; M428-F436 HydrophobicContact CE-CD2 4.05Å; M428-F436 HydrophobicContact CE-CG 4.23Å; M428-F436 HydrophobicContact SD-CB 4.41Å; M428-V477 HydrophobicContact CE-CG1 3.59Å; M428-V481 HydrophobicContact CE-CG2 4.47Å
429	T	88.4	Confident	90.8	Very high	53 Å²	53	28.6 Å²	28.6	33%	0.325	15%	0.149	S	C	.	.			trans	-69.5	162.9	164	69.3	0	0	0	0	109.7	T431 D432 A433 E458	T429-T431 PolarHBondContact O-N 3.26Å; T429-T431 PolarHBondContact OG1-N 2.78Å; T429-D432 PolarHBondContact O-N 3.25Å; T429-D432 WeakPolarHBondContact OG1-CB 3.11Å; T429-D432 PolarHBondContact OG1-N 3.06Å; T429-D432 PolarHBondContact OG1-OD2 3.01Å; T429-A433 WeakPolarHBondContact O-CB 3.44Å; T429-A433 PolarHBondContact O-N 3.3Å; T429-E458 WeakPolarHBondContact CA-OE1 3.5Å; T429-E458 WeakPolarHBondContact CB-OE1 3.47Å
430	M	93.3	Very high	90.4	Very high	6 Å²	6	32.9 Å²	32.9	3%	0.03	17%	0.167	C	C	.	.	H	α-helix	trans	-54	-42.6	172.6	-176.6	-74.7	-74.4	0	0	110.7	M423 Y434 M451 L454 L455 E458	M423-M430 HydrophobicContact CE-CB 3.87Å; M423-M430 HydrophobicContact CE-CG 4.34Å; M423-M430 HydrophobicContact SD-CB 3.85Å; M423-M430 HydrophobicContact SD-CG 3.99Å; M430-Y434 VanDerWaalsContact O-CB 3.25Å; M430-Y434 WeakPolarHBondContact O-CB 3.35Å; M430-Y434 PolarHBondContact O-N 3.1Å; M430-M451 HydrophobicContact CE-CE 3.71Å; M430-M451 HydrophobicContact SD-CE 3.4Å; M430-M451 WeakPolarHBondContact SD-CE 3.47Å; M430-L454 HydrophobicContact CG-CB 3.76Å; M430-L455 HydrophobicContact CE-CD2 3.31Å; M430-L455 HydrophobicContact CE-CG 3.78Å; M430-E458 HydrophobicContact CB-CB 4.23Å; M430-E458 HydrophobicContact CB-CG 4.49Å; M430-E458 WeakPolarHBondContact CB-OE2 3.4Å; M430-E458 PolarHBondContact N-OE1 2.85Å
431	T	84.3	Confident	90.1	Very high	37 Å²	37	33 Å²	33	23%	0.227	17%	0.168	C	C	.	.	H	α-helix	trans	-66.1	-42.2	-179.6	-61.6	0	0	0	0	111.8	T429 K435	T429-T431 PolarHBondContact O-N 3.26Å; T429-T431 PolarHBondContact OG1-N 2.78Å; T431-K435 HydrophobicContact CG2-CD 4.17Å; T431-K435 WeakPolarHBondContact O-CB 3.25Å; T431-K435 VanDerWaalsContact O-CG 3.27Å; T431-K435 WeakPolarHBondContact O-CG 2.85Å; T431-K435 PolarHBondContact O-N 2.95Å
432	D	84.3	Confident	89.4	Confident	48 Å²	48	36.3 Å²	36.3	26%	0.257	19%	0.189	S	C	.	.	H	α-helix	trans	-71.7	-42.3	-179.3	-60.2	-36.2	0	0	0	111.2	M428 T429 Y434 K435 F436	M428-D432 HydrophobicContact CB-CB 4.35Å; M428-D432 HydrophobicContact CG-CB 4.48Å; T429-D432 PolarHBondContact O-N 3.25Å; T429-D432 WeakPolarHBondContact OG1-CB 3.11Å; T429-D432 PolarHBondContact OG1-N 3.06Å; T429-D432 PolarHBondContact OG1-OD2 3.01Å; D432-Y434 PolarHBondContact O-N 3.25Å; D432-K435 PolarHBondContact O-N 3.27Å; D432-F436 VanDerWaalsContact O-CB 3.29Å; D432-F436 WeakPolarHBondContact O-CB 3.4Å; D432-F436 PolarHBondContact O-N 2.82Å
433	A	92.4	Very high	88.7	Confident	0 Å²	0	37 Å²	37	0%	0	19%	0.193	C	C	.	.	H	α-helix	trans	-61.1	-44.3	174	0	0	0	0	0	111.3	I419 L422 M423 M428 T429 K435 F436 V437	I419-A433 HydrophobicContact CG2-CB 3.9Å; L422-A433 HydrophobicContact CB-CB 4.05Å; M423-A433 HydrophobicContact CG-CB 3.81Å; M428-A433 HydrophobicContact CB-CB 4.08Å; M428-A433 HydrophobicContact SD-CB 4.41Å; T429-A433 WeakPolarHBondContact O-CB 3.44Å; T429-A433 PolarHBondContact O-N 3.3Å; A433-K435 PolarHBondContact O-N 3.49Å; A433-F436 PolarHBondContact O-N 3.24Å; A433-V437 WeakPolarHBondContact O-CG2 3.25Å; A433-V437 PolarHBondContact O-N 3.28Å
434	Y	92.4	Very high	88.4	Confident	8 Å²	8	37 Å²	37	3%	0.031	19%	0.193	C	C	.	.	H	α-helix	trans	-57.7	-50.2	173.7	177.8	-82	0	0	0	111.6	F177 N181 I419 M430 D432 F436 V437 K438 P446 M451	F177-Y434 HydrophobicContact CE1-CD1 4.11Å; F177-Y434 HydrophobicContact CE1-CE1 4.18Å; F177-Y434 AromaticContact CZ-CD1 3.94Å; F177-Y434 HydrophobicContact CZ-CD1 3.94Å; F177-Y434 AromaticContact CZ-CE1 3.94Å; F177-Y434 HydrophobicContact CZ-CE1 3.94Å; N181-Y434 PolarHBondContact OD1-OH 3.47Å; I419-Y434 HydrophobicContact CD1-CD2 3.83Å; I419-Y434 HydrophobicContact CD1-CG 4.43Å; M430-Y434 VanDerWaalsContact O-CB 3.25Å; M430-Y434 WeakPolarHBondContact O-CB 3.35Å; M430-Y434 PolarHBondContact O-N 3.1Å; D432-Y434 PolarHBondContact O-N 3.25Å; Y434-F436 VanDerWaalsContact C-N 3.33Å; Y434-F436 PolarHBondContact O-N 3.11Å; Y434-V437 PolarHBondContact O-N 2.8Å; Y434-K438 HydrophobicContact CD1-CB 4.46Å; Y434-K438 HydrophobicContact CE1-CB 4.25Å; Y434-K438 HydrophobicContact CE1-CG 4.36Å; Y434-K438 VanDerWaalsContact O-CB 3.27Å; Y434-K438 WeakPolarHBondContact O-CB 3.34Å; Y434-K438 PolarHBondContact O-N 3.17Å; Y434-P446 HydrophobicContact CE2-CG 4.35Å; Y434-M451 HydrophobicContact CD2-CE 4.31Å; Y434-M451 HydrophobicContact CD2-SD 4.02Å; Y434-M451 HydrophobicContact CE2-SD 4.03Å
435	K	85.1	Confident	87.9	Confident	92 Å²	92	38 Å²	38	40%	0.4	20%	0.2	S	C	.	.	H	α-helix	trans	-62.8	-39.5	179.7	-75.9	172.4	-177.2	169.3	0	112.1	T431 D432 A433 K438 G439	T431-K435 HydrophobicContact CG2-CD 4.17Å; T431-K435 WeakPolarHBondContact O-CB 3.25Å; T431-K435 VanDerWaalsContact O-CG 3.27Å; T431-K435 WeakPolarHBondContact O-CG 2.85Å; T431-K435 PolarHBondContact O-N 2.95Å; D432-K435 PolarHBondContact O-N 3.27Å; A433-K435 PolarHBondContact O-N 3.49Å; K435-K438 PolarHBondContact O-N 2.99Å; K435-G439 PolarHBondContact O-N 3.35Å
436	F	90.1	Very high	87.6	Confident	43 Å²	43	38.1 Å²	38.1	19%	0.189	20%	0.201	C	C	.	.	H	α-helix	trans	-59.6	-49.7	177.1	177.6	-93.8	0	0	0	111	I324 L422 M428 D432 A433 Y434 G439 K440 V477	I324-F436 HydrophobicContact CG2-CD1 4.4Å; I324-F436 HydrophobicContact CG2-CE1 3.85Å; L422-F436 HydrophobicContact CD1-CD1 3.58Å; L422-F436 HydrophobicContact CD1-CE1 4.04Å; M428-F436 HydrophobicContact CE-CB 4.44Å; M428-F436 HydrophobicContact CE-CD2 4.05Å; M428-F436 HydrophobicContact CE-CG 4.23Å; M428-F436 HydrophobicContact SD-CB 4.41Å; D432-F436 VanDerWaalsContact O-CB 3.29Å; D432-F436 WeakPolarHBondContact O-CB 3.4Å; D432-F436 PolarHBondContact O-N 2.82Å; A433-F436 PolarHBondContact O-N 3.24Å; Y434-F436 VanDerWaalsContact C-N 3.33Å; Y434-F436 PolarHBondContact O-N 3.11Å; F436-G439 PolarHBondContact O-N 3.32Å; F436-K440 HydrophobicContact CE1-CD 4.12Å; F436-K440 HydrophobicContact CZ-CD 4.17Å; F436-K440 PolarHBondContact O-N 3.02Å; F436-V477 HydrophobicContact CE2-CG1 4.16Å; F436-V477 HydrophobicContact CZ-CG1 4.09Å
437	V	94.6	Very high	87.2	Confident	0 Å²	0	39.6 Å²	39.6	0%	0	21%	0.209	C	C	.	.	H	α-helix	trans	-67.6	-39.9	178	-173.4	0	0	0	0	110.5	I324 L330 V418 I419 L422 A433 Y434 G439 K440 R441 I444	I324-V437 HydrophobicContact CD1-CG1 3.9Å; I324-V437 HydrophobicContact CG2-CG2 4.37Å; L330-V437 HydrophobicContact CD2-CG1 3.75Å; V418-V437 HydrophobicContact CG1-CG1 4.35Å; V418-V437 HydrophobicContact CG1-CG2 3.78Å; I419-V437 HydrophobicContact CG1-CB 4.29Å; I419-V437 HydrophobicContact CG1-CG2 3.93Å; L422-V437 HydrophobicContact CD1-CG2 3.53Å; A433-V437 WeakPolarHBondContact O-CG2 3.25Å; A433-V437 PolarHBondContact O-N 3.28Å; Y434-V437 PolarHBondContact O-N 2.8Å; V437-G439 VanDerWaalsContact C-N 3.35Å; V437-G439 PolarHBondContact O-N 3.19Å; V437-K440 PolarHBondContact O-N 3.36Å; V437-K440 VanDerWaalsContact O-N 3.16Å; V437-R441 PolarHBondContact O-N 3.35Å; V437-I444 HydrophobicContact CB-CD1 3.64Å; V437-I444 HydrophobicContact CG1-CD1 3.58Å; V437-I444 HydrophobicContact CG1-CG2 4.15Å
438	K	90.1	Very high	86.6	Confident	39 Å²	39	35.4 Å²	35.4	17%	0.17	20%	0.2	C	C	.	.	H	α-helix	trans	-63.9	-38.2	178.2	-172.5	71.9	166.8	-178.9	0	112.1	S284 Y434 K435 K440 R441 P442 I444	S284-K438 PolarHBondContact OG-NZ 2.86Å; Y434-K438 HydrophobicContact CD1-CB 4.46Å; Y434-K438 HydrophobicContact CE1-CB 4.25Å; Y434-K438 HydrophobicContact CE1-CG 4.36Å; Y434-K438 VanDerWaalsContact O-CB 3.27Å; Y434-K438 WeakPolarHBondContact O-CB 3.34Å; Y434-K438 PolarHBondContact O-N 3.17Å; K435-K438 PolarHBondContact O-N 2.99Å; K438-K440 PolarHBondContact O-N 3.05Å; K438-R441 CarbonylContact O-C 3.47Å; K438-R441 VanDerWaalsContact O-C 3.23Å; K438-P442 WeakPolarHBondContact CD-O 3.09Å; K438-P442 WeakPolarHBondContact CE-O 3.46Å; K438-P442 PolarHBondContact NZ-O 3.03Å; K438-P442 VanDerWaalsContact O-CA 3.26Å; K438-P442 WeakPolarHBondContact O-CA 3.2Å; K438-I444 HydrophobicContact CB-CD1 3.86Å; K438-I444 HydrophobicContact CB-CG1 3.98Å; K438-I444 HydrophobicContact CD-CD1 4.36Å; K438-I444 HydrophobicContact CD-CG1 3.53Å; K438-I444 HydrophobicContact CG-CG1 4.36Å; K438-I444 VanDerWaalsContact N-CD1 3.28Å; K438-I444 PolarHBondContact NZ-O 3.36Å
439	G	85.6	Confident	86.2	Confident	66 Å²	66	36.7 Å²	36.7	68%	0.68	21%	0.207	S	C	*	.	H	α-helix	trans	-63.6	-29.2	176	0	0	0	0	0	112.8	K435 F436 V437	K435-G439 PolarHBondContact O-N 3.35Å; F436-G439 PolarHBondContact O-N 3.32Å; V437-G439 VanDerWaalsContact C-N 3.35Å; V437-G439 PolarHBondContact O-N 3.19Å
440	K	90.4	Very high	86.2	Confident	90 Å²	90	34.1 Å²	34.1	39%	0.391	19%	0.191	S	C	.	.	H	α-helix	trans	-89.9	-41.3	176.7	-68.1	-174.8	161.4	-150.5	0	113.3	T322 P323 I324 F436 V437 K438	T322-K440 HydrophobicContact CG2-CB 3.81Å; T322-K440 VanDerWaalsContact CG2-O 3.28Å; T322-K440 WeakPolarHBondContact CG2-O 3.44Å; P323-K440 WeakPolarHBondContact O-CD 3.22Å; P323-K440 PolarHBondContact O-NZ 2.72Å; I324-K440 HydrophobicContact CD1-CB 4.2Å; I324-K440 HydrophobicContact CD1-CD 4.33Å; I324-K440 PolarHBondContact O-NZ 3Å; F436-K440 HydrophobicContact CE1-CD 4.12Å; F436-K440 HydrophobicContact CZ-CD 4.17Å; F436-K440 PolarHBondContact O-N 3.02Å; V437-K440 PolarHBondContact O-N 3.36Å; V437-K440 VanDerWaalsContact O-N 3.16Å; K438-K440 PolarHBondContact O-N 3.05Å
441	R	91.1	Very high	85.9	Confident	4 Å²	4	34.1 Å²	34.1	2%	0.015	19%	0.191	C	C	.	.			trans	-122.3	89.6	176.9	-170.9	172.1	-175.6	80.8	-4	109	A319 E320 T322 A409 G410 V437 K438 I443 I444	A319-R441 PolarHBondContact O-NH1 3.06Å; A319-R441 PolarHBondContact O-NH2 2.93Å; E320-R441 PolarHBondContact O-NH1 2.8Å; T322-R441 HydrophobicContact CG2-CB 3.92Å; T322-R441 PolarHBondContact OG1-NH1 2.83Å; A409-R441 PolarHBondContact O-NH2 2.73Å; G410-R441 PolarHBondContact O-NE 2.96Å; V437-R441 PolarHBondContact O-N 3.35Å; K438-R441 CarbonylContact O-C 3.47Å; K438-R441 VanDerWaalsContact O-C 3.23Å; R441-I443 HydrophobicContact CG-CG1 3.76Å; R441-I443 PolarHBondContact O-N 3.38Å; R441-I444 HydrophobicContact CB-CG2 3.84Å; R441-I444 HydrophobicContact CG-CG2 3.82Å; R441-I444 WeakPolarHBondContact O-CG2 3.14Å; R441-I444 PolarHBondContact O-N 2.79Å; R441-I444 VanDerWaalsContact O-N 3.13Å
442	P	84.1	Confident	85.5	Confident	69 Å²	69	33.7 Å²	33.7	45%	0.448	20%	0.195	S	C	.	.	T	Hydrogen-bonded Turn	trans	-59.3	-21.5	-175.6	-27.9	36.2	0	0	0	114.7	P314 K438 I444	P314-P442 HydrophobicContact CG-CB 3.94Å; K438-P442 WeakPolarHBondContact CD-O 3.09Å; K438-P442 WeakPolarHBondContact CE-O 3.46Å; K438-P442 PolarHBondContact NZ-O 3.03Å; K438-P442 VanDerWaalsContact O-CA 3.26Å; K438-P442 WeakPolarHBondContact O-CA 3.2Å; P442-I444 VanDerWaalsContact C-N 3.33Å; P442-I444 PolarHBondContact O-N 3.45Å
443	I	80.6	Confident	85.9	Confident	15 Å²	15	32 Å²	32	8%	0.077	19%	0.185	C	C	.	.	T	Hydrogen-bonded Turn	trans	-80.7	-7.9	-178.7	68.7	157.1	0	0	0	114.1	P314 I316 A319 V411 R441 S445	P314-I443 HydrophobicContact CB-CG2 4Å; P314-I443 HydrophobicContact CG-CG2 4.1Å; P314-I443 WeakPolarHBondContact O-CG2 3.43Å; I316-I443 HydrophobicContact CG1-CB 4.45Å; I316-I443 HydrophobicContact CG1-CG2 4.34Å; I316-I443 HydrophobicContact CG2-CD1 4.34Å; A319-I443 HydrophobicContact CB-CD1 3.39Å; A319-I443 HydrophobicContact CB-CG1 4.04Å; A319-I443 HydrophobicContact CB-CG2 4.43Å; V411-I443 WeakPolarHBondContact CG1-O 3.45Å; V411-I443 HydrophobicContact CG2-CD1 3.74Å; V411-I443 HydrophobicContact CG2-CG1 4.24Å; R441-I443 HydrophobicContact CG-CG1 3.76Å; R441-I443 PolarHBondContact O-N 3.38Å; I443-S445 PolarHBondContact O-N 2.74Å
444	I	88.4	Confident	86.1	Confident	0 Å²	0	32 Å²	32	0%	0	19%	0.185	C	C	.	.			trans	-61	138.5	-179.2	70.9	172.4	0	0	0	110.8	L330 V411 A415 I419 V437 K438 R441 P442	L330-I444 HydrophobicContact CD2-CG2 3.88Å; V411-I444 WeakPolarHBondContact O-CA 3.42Å; A415-I444 HydrophobicContact CB-CB 3.94Å; A415-I444 HydrophobicContact CB-CG2 3.78Å; I419-I444 HydrophobicContact CD1-CD1 4.35Å; V437-I444 HydrophobicContact CB-CD1 3.64Å; V437-I444 HydrophobicContact CG1-CD1 3.58Å; V437-I444 HydrophobicContact CG1-CG2 4.15Å; K438-I444 HydrophobicContact CB-CD1 3.86Å; K438-I444 HydrophobicContact CB-CG1 3.98Å; K438-I444 HydrophobicContact CD-CD1 4.36Å; K438-I444 HydrophobicContact CD-CG1 3.53Å; K438-I444 HydrophobicContact CG-CG1 4.36Å; K438-I444 VanDerWaalsContact N-CD1 3.28Å; K438-I444 PolarHBondContact NZ-O 3.36Å; R441-I444 HydrophobicContact CB-CG2 3.84Å; R441-I444 HydrophobicContact CG-CG2 3.82Å; R441-I444 WeakPolarHBondContact O-CG2 3.14Å; R441-I444 PolarHBondContact O-N 2.79Å; R441-I444 VanDerWaalsContact O-N 3.13Å; P442-I444 VanDerWaalsContact C-N 3.33Å; P442-I444 PolarHBondContact O-N 3.45Å
445	S	83.7	Confident	86	Confident	21 Å²	21	35.8 Å²	35.8	15%	0.147	21%	0.205	C	C	.	.			trans	-160	73.1	178.8	-163.5	0	0	0	0	108.8	V411 I443 N447	V411-S445 CarbonylContact O-C 3.56Å; V411-S445 PolarHBondContact O-N 3.12Å; I443-S445 PolarHBondContact O-N 2.74Å; S445-N447 PolarHBondContact O-N 3.34Å
446	P	85.6	Confident	86.3	Confident	10 Å²	10	36.2 Å²	36.2	7%	0.065	21%	0.209	C	C	.	.			trans	-47.7	136.5	168.1	-27.2	34.3	0	0	0	112.1	A415 I419 Y434 F450 M451	A415-P446 HydrophobicContact CB-CG 4.32Å; I419-P446 HydrophobicContact CD1-CG 4.02Å; Y434-P446 HydrophobicContact CE2-CG 4.35Å; P446-F450 HydrophobicContact CB-CB 4.33Å; P446-M451 HydrophobicContact CB-CG 4.12Å; P446-M451 HydrophobicContact CB-SD 3.78Å; P446-M451 HydrophobicContact CG-SD 4.17Å
447	N	76.9	Confident	86.6	Confident	33 Å²	33	34.5 Å²	34.5	18%	0.176	20%	0.201	C	C	.	.			trans	-65.2	163.5	176.5	77	47.2	0	0	0	111.6	D376 S412 S445 N449 F450 M451	D376-N447 PolarHBondContact OD1-ND2 2.85Å; S412-N447 PolarHBondContact OG-N 2.83Å; S412-N447 VanDerWaalsContact OG-N 3.15Å; S445-N447 PolarHBondContact O-N 3.34Å; N447-N449 VanDerWaalsContact C-N 3.28Å; N447-N449 PolarHBondContact O-N 2.98Å; N447-N449 WeakPolarHBondContact OD1-CA 3.37Å; N447-N449 WeakPolarHBondContact OD1-CB 3.45Å; N447-N449 PolarHBondContact OD1-N 3.47Å; N447-F450 WeakPolarHBondContact ND2-CD2 3.45Å; N447-F450 WeakPolarHBondContact ND2-CE2 3.5Å; N447-F450 WeakPolarHBondContact ND2-CZ 3.45Å; N447-F450 PolarHBondContact O-N 3.43Å; N447-F450 VanDerWaalsContact O-N 3.11Å; N447-F450 WeakPolarHBondContact OD1-CG 3.44Å; N447-F450 PolarHBondContact OD1-N 3.03Å; N447-M451 WeakPolarHBondContact O-CG 3.4Å; N447-M451 PolarHBondContact O-N 3.01Å
448	L	69.7	Low	86.6	Confident	95 Å²	95	36 Å²	36	50%	0.497	21%	0.208	S	C	.	.	H	α-helix	trans	-60.4	-33.8	-175.1	-69.2	-176.3	0	0	0	114.4	M178 M451 G452	M178-L448 HydrophobicContact CB-CD2 3.92Å; M178-L448 HydrophobicContact CG-CD2 4.07Å; M178-L448 HydrophobicContact SD-CD2 4.09Å; L448-M451 PolarHBondContact O-N 3Å; L448-G452 PolarHBondContact O-N 3.39Å
449	N	79.1	Confident	86.6	Confident	41 Å²	41	39.9 Å²	39.9	22%	0.219	23%	0.227	C	C	.	.	H	α-helix	trans	-67.3	-41.9	177.7	165	54.5	0	0	0	110.7	S377 N378 Q380 N447 G452 Q453	S377-N449 PolarHBondContact O-ND2 3.16Å; N378-N449 HydrophobicContact CB-CB 4.45Å; N378-N449 VanDerWaalsContact O-CB 3.32Å; N378-N449 WeakPolarHBondContact O-CB 3.18Å; Q380-N449 PolarHBondContact N-ND2 3.15Å; Q380-N449 PolarHBondContact O-ND2 3.21Å; N447-N449 VanDerWaalsContact C-N 3.28Å; N447-N449 PolarHBondContact O-N 2.98Å; N447-N449 WeakPolarHBondContact OD1-CA 3.37Å; N447-N449 WeakPolarHBondContact OD1-CB 3.45Å; N447-N449 PolarHBondContact OD1-N 3.47Å; N449-G452 PolarHBondContact O-N 2.76Å; N449-Q453 PolarHBondContact ND2-NE2 2.89Å; N449-Q453 VanDerWaalsContact ND2-NE2 3.17Å; N449-Q453 WeakPolarHBondContact O-CG 3.33Å; N449-Q453 PolarHBondContact O-N 3.42Å; N449-Q453 PolarHBondContact OD1-NE2 3.33Å
450	F	88.9	Confident	87	Confident	0 Å²	0	38.5 Å²	38.5	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-67.5	-36.7	174.2	-62	-20.9	0	0	0	112.7	D376 Q380 L382 S412 R413 T416 P446 N447 G452 Q453 L454	D376-F450 VanDerWaalsContact OD1-CE2 3.29Å; D376-F450 WeakPolarHBondContact OD1-CE2 3.4Å; Q380-F450 HydrophobicContact CB-CE1 3.85Å; Q380-F450 HydrophobicContact CB-CZ 4.06Å; Q380-F450 HydrophobicContact CG-CE1 4.13Å; Q380-F450 HydrophobicContact CG-CZ 4.24Å; Q380-F450 WeakPolarHBondContact O-CE1 3.4Å; L382-F450 HydrophobicContact CB-CD1 4.24Å; L382-F450 HydrophobicContact CB-CE1 4.19Å; L382-F450 HydrophobicContact CD1-CD1 3.67Å; L382-F450 HydrophobicContact CD1-CD2 3.75Å; L382-F450 HydrophobicContact CD1-CE1 3.5Å; L382-F450 HydrophobicContact CD1-CE2 3.59Å; L382-F450 HydrophobicContact CD1-CG 3.81Å; L382-F450 HydrophobicContact CD1-CZ 3.48Å; L382-F450 VanDerWaalsContact CD1-CZ 3.48Å; L382-F450 HydrophobicContact CG-CD1 3.96Å; L382-F450 HydrophobicContact CG-CE1 3.52Å; L382-F450 HydrophobicContact CG-CE2 4.41Å; L382-F450 HydrophobicContact CG-CZ 3.79Å; S412-F450 WeakPolarHBondContact OG-CD2 3.4Å; S412-F450 WeakPolarHBondContact OG-CE2 3.35Å; R413-F450 HydrophobicContact CB-CE2 4.42Å; R413-F450 HydrophobicContact CG-CE2 3.6Å; R413-F450 HydrophobicContact CG-CZ 3.99Å; T416-F450 HydrophobicContact CG2-CB 3.83Å; T416-F450 HydrophobicContact CG2-CG 4.28Å; T416-F450 WeakPolarHBondContact OG1-CB 3.18Å; P446-F450 HydrophobicContact CB-CB 4.33Å; N447-F450 WeakPolarHBondContact ND2-CD2 3.45Å; N447-F450 WeakPolarHBondContact ND2-CE2 3.5Å; N447-F450 WeakPolarHBondContact ND2-CZ 3.45Å; N447-F450 PolarHBondContact O-N 3.43Å; N447-F450 VanDerWaalsContact O-N 3.11Å; N447-F450 WeakPolarHBondContact OD1-CG 3.44Å; N447-F450 PolarHBondContact OD1-N 3.03Å; F450-G452 VanDerWaalsContact C-N 3.34Å; F450-G452 PolarHBondContact O-N 3.45Å; F450-Q453 WeakPolarHBondContact O-CB 3.31Å; F450-Q453 PolarHBondContact O-N 3.36Å; F450-L454 WeakPolarHBondContact O-CG 3.41Å; F450-L454 PolarHBondContact O-N 2.91Å
451	M	87.3	Confident	87	Confident	5 Å²	5	34.6 Å²	34.6	3%	0.025	19%	0.188	C	C	.	.	H	α-helix	trans	-62.2	-41	172.4	-69.6	-59	-40	0	0	112.2	M178 M430 Y434 P446 N447 L448 L454 L455	M178-M451 HydrophobicContact CE-CE 3.65Å; M178-M451 HydrophobicContact CE-CG 4.32Å; M178-M451 HydrophobicContact CE-SD 4.4Å; M178-M451 HydrophobicContact SD-CB 3.71Å; M178-M451 HydrophobicContact SD-CE 4.09Å; M178-M451 HydrophobicContact SD-CG 3.57Å; M178-M451 VanDerWaalsContact SD-CG 3.57Å; M178-M451 HydrophobicContact SD-SD 4.4Å; M430-M451 HydrophobicContact CE-CE 3.71Å; M430-M451 HydrophobicContact SD-CE 3.4Å; M430-M451 WeakPolarHBondContact SD-CE 3.47Å; Y434-M451 HydrophobicContact CD2-CE 4.31Å; Y434-M451 HydrophobicContact CD2-SD 4.02Å; Y434-M451 HydrophobicContact CE2-SD 4.03Å; P446-M451 HydrophobicContact CB-CG 4.12Å; P446-M451 HydrophobicContact CB-SD 3.78Å; P446-M451 HydrophobicContact CG-SD 4.17Å; N447-M451 WeakPolarHBondContact O-CG 3.4Å; N447-M451 PolarHBondContact O-N 3.01Å; L448-M451 PolarHBondContact O-N 3Å; M451-L454 HydrophobicContact CE-CD1 4.47Å; M451-L454 PolarHBondContact O-N 3.38Å; M451-L454 HydrophobicContact SD-CD1 4.16Å; M451-L455 WeakPolarHBondContact O-CG 3.35Å; M451-L455 PolarHBondContact O-N 3.22Å; M451-L455 VanDerWaalsContact O-N 3.08Å
452	G	75.7	Confident	87	Confident	29 Å²	29	39.1 Å²	39.1	30%	0.299	21%	0.212	S	C	.	.	H	α-helix	trans	-60.6	-45.4	172.7	0	0	0	0	0	112.2	L448 N449 F450 L454 L455 E456	L448-G452 PolarHBondContact O-N 3.39Å; N449-G452 PolarHBondContact O-N 2.76Å; F450-G452 VanDerWaalsContact C-N 3.34Å; F450-G452 PolarHBondContact O-N 3.45Å; G452-L454 VanDerWaalsContact C-N 3.32Å; G452-L454 PolarHBondContact O-N 3.02Å; G452-L455 WeakPolarHBondContact O-CB 3.42Å; G452-L455 PolarHBondContact O-N 3.09Å; G452-L455 VanDerWaalsContact O-N 3.15Å; G452-E456 WeakPolarHBondContact O-CG 3.28Å; G452-E456 PolarHBondContact O-N 3.13Å
453	Q	92.2	Very high	87.3	Confident	13 Å²	13	41 Å²	41	6%	0.061	22%	0.218	C	C	.	.	H	α-helix	trans	-61.8	-36.5	176.3	-77.4	175.4	53.9	0	0	113.5	Q380 R383 N449 F450 F457	Q380-Q453 PolarHBondContact O-NE2 3.21Å; R383-Q453 HydrophobicContact CG-CB 3.62Å; R383-Q453 HydrophobicContact CG-CG 3.85Å; R383-Q453 VanDerWaalsContact N-OE1 3.14Å; N449-Q453 PolarHBondContact ND2-NE2 2.89Å; N449-Q453 VanDerWaalsContact ND2-NE2 3.17Å; N449-Q453 WeakPolarHBondContact O-CG 3.33Å; N449-Q453 PolarHBondContact O-N 3.42Å; N449-Q453 PolarHBondContact OD1-NE2 3.33Å; F450-Q453 WeakPolarHBondContact O-CB 3.31Å; F450-Q453 PolarHBondContact O-N 3.36Å; Q453-F457 VanDerWaalsContact O-CB 3.28Å; Q453-F457 WeakPolarHBondContact O-CB 3.41Å; Q453-F457 PolarHBondContact O-N 3.24Å
454	L	95.5	Very high	87.6	Confident	0 Å²	0	42.9 Å²	42.9	0%	0	24%	0.242	C	C	.	.	H	α-helix	trans	-67.8	-37.8	174.1	-73.2	170.9	0	0	0	112	F386 T416 I419 A420 M423 M430 F450 M451 G452 F457 E458	F386-L454 HydrophobicContact CE2-CD2 4.5Å; F386-L454 HydrophobicContact CZ-CD2 4.16Å; T416-L454 HydrophobicContact CG2-CD1 4.09Å; T416-L454 HydrophobicContact CG2-CD2 4.13Å; T416-L454 HydrophobicContact CG2-CG 4.01Å; I419-L454 HydrophobicContact CB-CD1 4.26Å; I419-L454 HydrophobicContact CB-CD2 4.38Å; I419-L454 HydrophobicContact CD1-CD1 4.39Å; I419-L454 HydrophobicContact CG2-CD1 3.9Å; I419-L454 HydrophobicContact CG2-CD2 4.05Å; A420-L454 HydrophobicContact CB-CD2 3.71Å; M423-L454 WeakPolarHBondContact CE-O 3.48Å; M423-L454 HydrophobicContact SD-CD2 4.14Å; M430-L454 HydrophobicContact CG-CB 3.76Å; F450-L454 WeakPolarHBondContact O-CG 3.41Å; F450-L454 PolarHBondContact O-N 2.91Å; M451-L454 HydrophobicContact CE-CD1 4.47Å; M451-L454 PolarHBondContact O-N 3.38Å; M451-L454 HydrophobicContact SD-CD1 4.16Å; G452-L454 VanDerWaalsContact C-N 3.32Å; G452-L454 PolarHBondContact O-N 3.02Å; L454-F457 PolarHBondContact O-N 3.36Å; L454-E458 PolarHBondContact O-N 2.9Å
455	L	90.8	Very high	87.6	Confident	87 Å²	87	47.8 Å²	47.8	46%	0.455	27%	0.271	S	S	.	.	H	α-helix	trans	-65.2	-45.8	175.2	-74.5	168.6	0	0	0	111.9	M430 M451 G452 F457 E458 E459	M430-L455 HydrophobicContact CE-CD2 3.31Å; M430-L455 HydrophobicContact CE-CG 3.78Å; M451-L455 WeakPolarHBondContact O-CG 3.35Å; M451-L455 PolarHBondContact O-N 3.22Å; M451-L455 VanDerWaalsContact O-N 3.08Å; G452-L455 WeakPolarHBondContact O-CB 3.42Å; G452-L455 PolarHBondContact O-N 3.09Å; G452-L455 VanDerWaalsContact O-N 3.15Å; L455-F457 VanDerWaalsContact C-N 3.28Å; L455-F457 PolarHBondContact O-N 3.26Å; L455-E458 WeakPolarHBondContact O-CB 3.22Å; L455-E458 PolarHBondContact O-N 3.24Å; L455-E459 PolarHBondContact O-N 2.98Å; L455-E459 VanDerWaalsContact O-N 3.08Å
456	E	91.3	Very high	87.8	Confident	101 Å²	101	48 Å²	48	47%	0.472	27%	0.272	S	S	.	.	H	α-helix	trans	-62.2	-39.1	174.7	-65.6	173.5	-174.8	0	0	111.4	R383 G452 E459 D460	R383-E456 IonicContact NH1-OE2 2.89Å; R383-E456 PolarHBondContact NH1-OE2 3.03Å; G452-E456 WeakPolarHBondContact O-CG 3.28Å; G452-E456 PolarHBondContact O-N 3.13Å; E456-E459 WeakPolarHBondContact O-CB 3.2Å; E456-E459 PolarHBondContact O-N 2.97Å; E456-D460 PolarHBondContact O-N 3.11Å
457	F	96.8	Very high	87.8	Confident	7 Å²	7	51.7 Å²	51.7	3%	0.031	30%	0.296	C	S	.	.	H	α-helix	trans	-64.8	-39.2	176.6	-174.4	-119	0	0	0	112.3	F386 F390 A420 M423 K424 Q453 L454 L455 E459 D460 L461 T466	F386-F457 AromaticContact CD2-CD1 3.99Å; F386-F457 HydrophobicContact CD2-CD1 3.99Å; F386-F457 AromaticContact CD2-CD2 3.82Å; F386-F457 HydrophobicContact CD2-CD2 3.82Å; F386-F457 HydrophobicContact CD2-CE1 4.08Å; F386-F457 AromaticContact CD2-CE2 3.9Å; F386-F457 HydrophobicContact CD2-CE2 3.9Å; F386-F457 AromaticContact CD2-CG 3.87Å; F386-F457 HydrophobicContact CD2-CG 3.87Å; F386-F457 HydrophobicContact CD2-CZ 4.04Å; F386-F457 HydrophobicContact CE2-CB 3.99Å; F386-F457 AromaticContact CE2-CD1 3.85Å; F386-F457 HydrophobicContact CE2-CD1 3.85Å; F386-F457 HydrophobicContact CE2-CD2 4.12Å; F386-F457 HydrophobicContact CE2-CE1 4.35Å; F386-F457 AromaticContact CE2-CG 3.72Å; F386-F457 HydrophobicContact CE2-CG 3.72Å; F390-F457 HydrophobicContact CE2-CE1 4.34Å; F390-F457 AromaticContact CE2-CZ 3.85Å; F390-F457 HydrophobicContact CE2-CZ 3.85Å; F390-F457 HydrophobicContact CZ-CE1 4.31Å; F390-F457 HydrophobicContact CZ-CZ 4.23Å; A420-F457 HydrophobicContact CB-CD1 4.14Å; A420-F457 HydrophobicContact CB-CE1 4.08Å; M423-F457 HydrophobicContact CE-CD1 3.87Å; K424-F457 HydrophobicContact CB-CE1 4.23Å; K424-F457 HydrophobicContact CB-CZ 4.08Å; K424-F457 HydrophobicContact CD-CZ 4.02Å; Q453-F457 VanDerWaalsContact O-CB 3.28Å; Q453-F457 WeakPolarHBondContact O-CB 3.41Å; Q453-F457 PolarHBondContact O-N 3.24Å; L454-F457 PolarHBondContact O-N 3.36Å; L455-F457 VanDerWaalsContact C-N 3.28Å; L455-F457 PolarHBondContact O-N 3.26Å; F457-E459 VanDerWaalsContact C-N 3.33Å; F457-E459 PolarHBondContact O-N 3.32Å; F457-D460 PolarHBondContact O-N 3.18Å; F457-L461 HydrophobicContact CD1-CD1 3.9Å; F457-L461 HydrophobicContact CD1-CG 4.42Å; F457-L461 HydrophobicContact CE1-CD1 3.59Å; F457-L461 HydrophobicContact CE1-CD2 4.42Å; F457-L461 HydrophobicContact CE1-CG 4.14Å; F457-L461 HydrophobicContact CE2-CD2 4.37Å; F457-L461 HydrophobicContact CE2-CG 4.36Å; F457-L461 HydrophobicContact CZ-CD1 4.02Å; F457-L461 HydrophobicContact CZ-CD2 4.01Å; F457-L461 HydrophobicContact CZ-CG 4.1Å; F457-L461 VanDerWaalsContact O-CG 3.28Å; F457-L461 WeakPolarHBondContact O-CG 3.49Å; F457-L461 PolarHBondContact O-N 2.89Å; F457-T466 HydrophobicContact CE2-CG2 3.93Å; F457-T466 HydrophobicContact CZ-CG2 4.38Å
458	E	94.1	Very high	88.3	Confident	31 Å²	31	53.1 Å²	53.1	15%	0.145	30%	0.299	C	S	.	.	H	α-helix	trans	-59.6	-43.9	172.1	-178.3	169.8	-130.3	0	0	112	M423 T429 M430 L454 L455 L461 N462	M423-E458 HydrophobicContact CE-CB 3.55Å; M423-E458 HydrophobicContact CE-CG 4.33Å; T429-E458 WeakPolarHBondContact CA-OE1 3.5Å; T429-E458 WeakPolarHBondContact CB-OE1 3.47Å; M430-E458 HydrophobicContact CB-CB 4.23Å; M430-E458 HydrophobicContact CB-CG 4.49Å; M430-E458 WeakPolarHBondContact CB-OE2 3.4Å; M430-E458 PolarHBondContact N-OE1 2.85Å; L454-E458 PolarHBondContact O-N 2.9Å; L455-E458 WeakPolarHBondContact O-CB 3.22Å; L455-E458 PolarHBondContact O-N 3.24Å; E458-L461 PolarHBondContact O-N 2.94Å; E458-N462 WeakPolarHBondContact O-CB 3.39Å; E458-N462 PolarHBondContact O-N 3.31Å; E458-N462 PolarHBondContact O-ND2 3.06Å
459	E	91.8	Very high	89	Confident	120 Å²	120	51.9 Å²	51.9	56%	0.561	29%	0.292	S	S	*	.	H	α-helix	trans	-60.5	-45.4	176.6	-177.8	167	-157.7	0	0	111.3	L455 E456 F457 L461 N462 N463	L455-E459 PolarHBondContact O-N 2.98Å; L455-E459 VanDerWaalsContact O-N 3.08Å; E456-E459 WeakPolarHBondContact O-CB 3.2Å; E456-E459 PolarHBondContact O-N 2.97Å; F457-E459 VanDerWaalsContact C-N 3.33Å; F457-E459 PolarHBondContact O-N 3.32Å; E459-L461 PolarHBondContact O-N 2.78Å; E459-N462 PolarHBondContact O-N 3.34Å; E459-N463 VanDerWaalsContact CG-ND2 3.28Å; E459-N463 WeakPolarHBondContact CG-ND2 3.45Å; E459-N463 WeakPolarHBondContact O-CB 3.47Å; E459-N463 VanDerWaalsContact O-CG 3.26Å; E459-N463 PolarHBondContact O-N 2.95Å; E459-N463 PolarHBondContact O-ND2 3.5Å
460	D	92.9	Very high	88.9	Confident	38 Å²	38	53.4 Å²	53.4	20%	0.203	30%	0.299	C	S	.	.	H	α-helix	trans	-63.7	-38.5	177.3	-75	-18.1	0	0	0	113	R383 E456 F457 N462 G464 V465 T466	R383-D460 IonicContact CZ-OD2 2.87Å; R383-D460 IonicContact NH1-OD2 3.48Å; R383-D460 IonicContact NH2-OD2 3.6Å; R383-D460 PolarHBondContact NH2-OD2 2.8Å; E456-D460 PolarHBondContact O-N 3.11Å; F457-D460 PolarHBondContact O-N 3.18Å; D460-N462 VanDerWaalsContact C-N 3.35Å; D460-G464 PolarHBondContact O-N 2.9Å; D460-G464 VanDerWaalsContact O-N 3.17Å; D460-V465 HydrophobicContact CB-CB 4.06Å; D460-V465 HydrophobicContact CB-CG1 4.44Å; D460-V465 PolarHBondContact O-N 3.33Å; D460-T466 PolarHBondContact O-N 3.49Å; D460-T466 VanDerWaalsContact O-N 3.11Å
461	L	91.4	Very high	87.4	Confident	8 Å²	8	55.2 Å²	55.2	4%	0.042	31%	0.311	C	S	.	.	H	α-helix	trans	-66.7	-35.9	174.7	-70.7	173.8	0	0	0	112.3	M423 K424 F457 E458 E459 T466 R468	M423-L461 HydrophobicContact CB-CD1 3.91Å; M423-L461 HydrophobicContact CE-CD1 4.25Å; K424-L461 HydrophobicContact CB-CD2 4.29Å; K424-L461 HydrophobicContact CD-CD2 4.31Å; K424-L461 HydrophobicContact CG-CD2 4.22Å; F457-L461 HydrophobicContact CD1-CD1 3.9Å; F457-L461 HydrophobicContact CD1-CG 4.42Å; F457-L461 HydrophobicContact CE1-CD1 3.59Å; F457-L461 HydrophobicContact CE1-CD2 4.42Å; F457-L461 HydrophobicContact CE1-CG 4.14Å; F457-L461 HydrophobicContact CE2-CD2 4.37Å; F457-L461 HydrophobicContact CE2-CG 4.36Å; F457-L461 HydrophobicContact CZ-CD1 4.02Å; F457-L461 HydrophobicContact CZ-CD2 4.01Å; F457-L461 HydrophobicContact CZ-CG 4.1Å; F457-L461 VanDerWaalsContact O-CG 3.28Å; F457-L461 WeakPolarHBondContact O-CG 3.49Å; F457-L461 PolarHBondContact O-N 2.89Å; E458-L461 PolarHBondContact O-N 2.94Å; E459-L461 PolarHBondContact O-N 2.78Å; L461-T466 HydrophobicContact CD2-CG2 3.69Å; L461-R468 HydrophobicContact CB-CG 4.15Å; L461-R468 HydrophobicContact CD2-CG 3.85Å; L461-R468 HydrophobicContact CG-CG 4.45Å
462	N	89.4	Confident	85.8	Confident	99 Å²	99	59.7 Å²	59.7	53%	0.529	34%	0.34	S	S	.	.	H	α-helix	trans	-78.3	-33.7	-179.2	-68.7	-19.7	0	0	0	112.4	E458 E459 D460 G464 R468	E458-N462 WeakPolarHBondContact O-CB 3.39Å; E458-N462 PolarHBondContact O-N 3.31Å; E458-N462 PolarHBondContact O-ND2 3.06Å; E459-N462 PolarHBondContact O-N 3.34Å; D460-N462 VanDerWaalsContact C-N 3.35Å; N462-G464 VanDerWaalsContact C-N 3.26Å; N462-R468 PolarHBondContact OD1-NH2 3.02Å
463	N	91.3	Very high	84.6	Confident	107 Å²	107	64.3 Å²	64.3	57%	0.572	35%	0.352	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81.7	-5.6	176.6	-67.7	-25.2	0	0	0	112.8	E459 V465	E459-N463 VanDerWaalsContact CG-ND2 3.28Å; E459-N463 WeakPolarHBondContact CG-ND2 3.45Å; E459-N463 WeakPolarHBondContact O-CB 3.47Å; E459-N463 VanDerWaalsContact O-CG 3.26Å; E459-N463 PolarHBondContact O-N 2.95Å; E459-N463 PolarHBondContact O-ND2 3.5Å; N463-V465 HydrophobicContact CB-CG2 4.16Å; N463-V465 PolarHBondContact O-N 3.03Å
464	G	86.7	Confident	83	Confident	56 Å²	56	64.5 Å²	64.5	58%	0.577	35%	0.353	S	S	*	.	T	Hydrogen-bonded Turn	trans	73.4	12.6	-178.9	0	0	0	0	0	114.3	D460 N462 T466	D460-G464 PolarHBondContact O-N 2.9Å; D460-G464 VanDerWaalsContact O-N 3.17Å; N462-G464 VanDerWaalsContact C-N 3.26Å; G464-T466 VanDerWaalsContact C-N 3.32Å
465	V	89.4	Confident	80.5	Confident	103 Å²	103	70.9 Å²	70.9	62%	0.624	39%	0.386	S	S	*	.	S	Bend	trans	-64.8	-43	172.1	177.3	0	0	0	0	109.5	D460 N463	D460-V465 HydrophobicContact CB-CB 4.06Å; D460-V465 HydrophobicContact CB-CG1 4.44Å; D460-V465 PolarHBondContact O-N 3.33Å; N463-V465 HydrophobicContact CB-CG2 4.16Å; N463-V465 PolarHBondContact O-N 3.03Å
466	T	86.5	Confident	78.5	Confident	24 Å²	24	68.9 Å²	68.9	15%	0.147	39%	0.386	C	S	.	.	S	Bend	trans	-105.5	126.3	168.7	-59.1	0	0	0	0	109	K424 F457 D460 L461 G464 R468	K424-T466 HydrophobicContact CD-CG2 4.07Å; F457-T466 HydrophobicContact CE2-CG2 3.93Å; F457-T466 HydrophobicContact CZ-CG2 4.38Å; D460-T466 PolarHBondContact O-N 3.49Å; D460-T466 VanDerWaalsContact O-N 3.11Å; L461-T466 HydrophobicContact CD2-CG2 3.69Å; G464-T466 VanDerWaalsContact C-N 3.32Å; T466-R468 PolarHBondContact O-N 3.01Å
467	P	86.9	Confident	76.6	Confident	88 Å²	88	65.2 Å²	65.2	57%	0.571	37%	0.371	S	S	*	.			trans	-68.8	132.5	177.3	27.5	-33.4	0	0	0	110.9	K424	K424-P467 VanDerWaalsContact CE-O 3.24Å; K424-P467 WeakPolarHBondContact CE-O 3.49Å
468	R	86.9	Confident	74.3	Confident	63 Å²	63	69.9 Å²	69.9	24%	0.238	39%	0.393	C	S	.	.			trans	-75.8	130.5	165.5	-74.1	-176.9	-175.4	-99.1	2.3	109.2	M423 T426 L461 N462 T466 L470	M423-R468 PolarHBondContact O-NH1 3.36Å; T426-R468 PolarHBondContact O-NH1 2.82Å; L461-R468 HydrophobicContact CB-CG 4.15Å; L461-R468 HydrophobicContact CD2-CG 3.85Å; L461-R468 HydrophobicContact CG-CG 4.45Å; N462-R468 PolarHBondContact OD1-NH2 3.02Å; T466-R468 PolarHBondContact O-N 3.01Å; R468-L470 HydrophobicContact CB-CD2 4.38Å; R468-L470 HydrophobicContact CB-CG 4.34Å
469	I	84.2	Confident	71.5	Confident	69 Å²	69	74.1 Å²	74.1	35%	0.354	42%	0.421	S	S	.	.			trans	-102	85	178.2	-57.9	176.9	0	0	0	106.9	K424 H425 T471	K424-I469 PolarHBondContact O-N 2.69Å; H425-I469 WeakPolarHBondContact CA-O 3.41Å; I469-T471 VanDerWaalsContact C-N 3.33Å; I469-T471 HydrophobicContact CG2-CG2 4.03Å; I469-T471 PolarHBondContact O-N 2.95Å
470	L	76.6	Confident	68.7	Low	73 Å²	73	74.1 Å²	74.1	38%	0.382	43%	0.429	S	S	.	.			trans	-82.3	81.8	179.3	-58.1	178.9	0	0	0	109.1	R427 R468	R427-L470 HydrophobicContact CG-CD1 3.98Å; R427-L470 HydrophobicContact CG-CD2 3.72Å; R427-L470 VanDerWaalsContact NE-CD1 3.27Å; R468-L470 HydrophobicContact CB-CD2 4.38Å; R468-L470 HydrophobicContact CB-CG 4.34Å
471	T	57.5	Low	65.7	Low	39 Å²	39	79.8 Å²	79.8	24%	0.239	47%	0.465	C	S	.	.			trans	-74	129.2	175.4	37.2	0	0	0	0	109.9	I469 K473 L474	I469-T471 VanDerWaalsContact C-N 3.33Å; I469-T471 HydrophobicContact CG2-CG2 4.03Å; I469-T471 PolarHBondContact O-N 2.95Å; T471-K473 PolarHBondContact O-N 3.29Å; T471-L474 PolarHBondContact O-N 3.38Å
472	P	54.4	Low	64.5	Low	98 Å²	98	83.4 Å²	83.4	64%	0.636	49%	0.486	S	S	*	.	G	3₁₀ helix	trans	-64.3	-1.5	174.1	25.7	-34.8	0	0	0	113.6	I475	P472-I475 HydrophobicContact CB-CD1 3.72Å; P472-I475 HydrophobicContact CB-CG1 4.48Å; P472-I475 WeakPolarHBondContact O-CD1 3.32Å; P472-I475 WeakPolarHBondContact O-CG1 3.2Å
473	K	51.2	Low	63.1	Low	127 Å²	127	82.6 Å²	82.6	55%	0.552	48%	0.483	S	S	*	.	G	3₁₀ helix	trans	-81.3	-15.5	-179.5	-65	-178.5	-178.9	173.9	0	114.1	T471	T471-K473 PolarHBondContact O-N 3.29Å
474	L	57.8	Low	61.6	Low	17 Å²	17	81.2 Å²	81.2	9%	0.089	48%	0.479	C	S	.	.	G	3₁₀ helix	trans	-99.4	11.1	175.2	-63.8	174.1	0	0	0	113.1	L325 F327 H425 T426 T471 G476 V477	L325-L474 HydrophobicContact CD1-CD2 4.08Å; F327-L474 HydrophobicContact CE1-CD2 3.79Å; F327-L474 HydrophobicContact CZ-CD2 4.18Å; H425-L474 HydrophobicContact CB-CD1 3.76Å; T426-L474 HydrophobicContact CG2-CD1 4.44Å; T471-L474 PolarHBondContact O-N 3.38Å; L474-G476 PolarHBondContact O-N 3.22Å; L474-V477 PolarHBondContact O-N 3.28Å
475	I	43.9	Very low	60.1	Low	133 Å²	133	82.7 Å²	82.7	68%	0.682	47%	0.473	S	S	*	.	T	Hydrogen-bonded Turn	trans	-57.2	121.7	177.5	-69	171.5	0	0	0	109.3	P472	P472-I475 HydrophobicContact CB-CD1 3.72Å; P472-I475 HydrophobicContact CB-CG1 4.48Å; P472-I475 WeakPolarHBondContact O-CD1 3.32Å; P472-I475 WeakPolarHBondContact O-CG1 3.2Å
476	G	47.6	Very low	58.3	Low	45 Å²	45	81.4 Å²	81.4	46%	0.464	46%	0.463	S	S	.	.	T	Hydrogen-bonded Turn	trans	124.9	-20.3	-175.5	0	0	0	0	0	114	L474 T479	L474-G476 PolarHBondContact O-N 3.22Å; G476-T479 PolarHBondContact O-OG1 2.75Å
477	V	50.9	Low	56.4	Low	25 Å²	25	85.3 Å²	85.3	15%	0.152	48%	0.484	C	S	.	.	S	Bend	trans	-80.1	-23.7	171.2	-173.7	0	0	0	0	111.4	L325 M428 F436 L474 T479	L325-V477 HydrophobicContact CD2-CG1 4.45Å; L325-V477 HydrophobicContact CD2-CG2 3.67Å; M428-V477 HydrophobicContact CE-CG1 3.59Å; F436-V477 HydrophobicContact CE2-CG1 4.16Å; F436-V477 HydrophobicContact CZ-CG1 4.09Å; L474-V477 PolarHBondContact O-N 3.28Å; V477-T479 VanDerWaalsContact C-N 3.34Å; V477-T479 PolarHBondContact O-N 3.02Å
478	E	49	Very low	54.2	Low	105 Å²	105	85.1 Å²	85.1	49%	0.491	48%	0.478	S	S	.	.	T	Hydrogen-bonded Turn	trans	-78.5	-10.1	-178.5	-57.9	-168.4	147.8	0	0	114.3	R427	R427-E478 PolarHBondContact N-OE1 3.39Å
479	T	35.9	Very low	51.7	Low	119 Å²	119	86.8 Å²	86.8	73%	0.73	50%	0.497	S	S	*	.	T	Hydrogen-bonded Turn	trans	-105.8	9.9	-171.2	38.6	0	0	0	0	115.9	G476 V477	G476-T479 PolarHBondContact O-OG1 2.75Å; V477-T479 VanDerWaalsContact C-N 3.34Å; V477-T479 PolarHBondContact O-N 3.02Å
480	V	32.9	Very low	49	Very low	120 Å²	120	88.3 Å²	88.3	73%	0.727	51%	0.509	S	S	*	.			trans	-134.9	69.4	174.8	-166.8	0	0	0	0	110.3
481	V	30.4	Very low	46.5	Very low	158 Å²	158	89.6 Å²	89.6	96%	0.958	52%	0.52	S	S	*	.			trans	-138.7	0	156.8	-176.9	0	0	0	0	108.7	M428	M428-V481 HydrophobicContact CE-CG2 4.47Å

Retrieved 481 of 481 residues in 79.4 ms (Link to these results)

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