A0A093HIW4_STRCA Loading...

Histamine N-methyltransferase

AlphaFold DB , UniProt , Accession A0A093HIW4, Species STRCA (Struthio camelus australis), Gene n/a, Length 292 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M44.9Very low81.5Confident244 Ų24476.7 Ų76.7100%1.20245%0.447SS*.  0125.20-68.9-160.1-86.200106.8S3M1-S3 PolarHBondContact O-N 2.84Å
2A55.2Low82Confident81 Ų8178.3 Ų78.367%0.66945%0.446SS*.PPolyproline II helixtrans-60.3135.4173.300000108.5
3S67.8Low82.7Confident73 Ų7375.3 Ų75.351%0.5144%0.443SS..PPolyproline II helixtrans-59.9142.1171.3174.50000108.7M1 M5M1-S3 PolarHBondContact O-N 2.84Å; S3-M5 PolarHBondContact O-N 3.3Å
4A86.8Confident83.5Confident77 Ų7773.4 Ų73.464%0.63643%0.425SS*.PPolyproline II helixtrans-58.1139.4172.800000110.3
5M93.9Very high84.1Confident44 Ų4470.7 Ų70.722%0.21741%0.405CS..PPolyproline II helixtrans-60.3142.4171.7-65.5-171.4-64.600109.8S3 H189 P191 T247 F250 A254 L258S3-M5 PolarHBondContact O-N 3.3Å; M5-H189 WeakPolarHBondContact CE-O 3.45Å; M5-P191 HydrophobicContact CB-CB 4.18Å; M5-P191 HydrophobicContact CB-CG 3.89Å; M5-T247 HydrophobicContact CB-CG2 3.87Å; M5-T247 HydrophobicContact CG-CG2 4.13Å; M5-T247 HydrophobicContact SD-CG2 4.31Å; M5-F250 HydrophobicContact SD-CD2 4.47Å; M5-F250 HydrophobicContact SD-CE2 4.49Å; M5-A254 HydrophobicContact SD-CB 3.9Å; M5-L258 HydrophobicContact CE-CD2 3.83Å; M5-L258 HydrophobicContact SD-CD2 4.14Å
6K93.4Very high84.5Confident124 Ų12469.5 Ų69.554%0.53940%0.399SS..  trans-131.2141.5179.5-63.8179.7-176.4176.10109.7L8 P191 T247 C248K6-L8 PolarHBondContact O-N 2.98Å; K6-P191 VanDerWaalsContact C-CG 3.46Å; K6-T247 CarbonylContact O-C 3.35Å; K6-T247 WeakPolarHBondContact O-CA 3.48Å; K6-C248 PolarHBondContact O-N 3.07Å
7S92.8Very high85.1Confident6 Ų671.1 Ų71.14%0.04240%0.403CS..BIsolated β-bridgetrans-55.3136.6175.5178.40000111.6I9 T10 P191 N193 E246S7-I9 VanDerWaalsContact C-N 3.26Å; S7-I9 PolarHBondContact O-N 3.41Å; S7-I9 WeakPolarHBondContact OG-CG2 3.19Å; S7-T10 PolarHBondContact O-N 3.16Å; S7-T10 VanDerWaalsContact O-N 3.15Å; S7-T10 PolarHBondContact O-OG1 3.14Å; S7-P191 VanDerWaalsContact CB-O 3.27Å; S7-P191 WeakPolarHBondContact CB-O 3.35Å; S7-N193 VanDerWaalsContact CB-ND2 3.28Å; S7-N193 WeakPolarHBondContact CB-ND2 3.32Å; S7-N193 PolarHBondContact OG-ND2 2.99Å; S7-E246 CarbonylContact C-O 3.6Å; S7-E246 WeakPolarHBondContact CA-O 3.49Å
8L92.6Very high85.7Confident0 Ų067.2 Ų67.20%038%0.38CS..G310 helixtrans-55.8-40.9178.5-177.159.6000112K6 T10 N11 R14 Y15 D242 F243 E246K6-L8 PolarHBondContact O-N 2.98Å; L8-T10 PolarHBondContact O-N 2.99Å; L8-N11 CarbonylContact O-C 3.55Å; L8-N11 PolarHBondContact O-N 2.8Å; L8-R14 HydrophobicContact CD1-CB 4.3Å; L8-R14 HydrophobicContact CD1-CG 4.02Å; L8-Y15 HydrophobicContact CD2-CD2 4.05Å; L8-Y15 HydrophobicContact CG-CD2 4.04Å; L8-D242 HydrophobicContact CD1-CB 4.34Å; L8-F243 HydrophobicContact CD2-CD2 4.3Å; L8-E246 PolarHBondContact N-O 3.23Å
9I88.3Confident86.1Confident40 Ų4066.9 Ų66.921%0.20538%0.375CS..G310 helixtrans-62.3-20.6-177.9-155.965.2000113.4S7 N11 Y15 Y147 L195S7-I9 VanDerWaalsContact C-N 3.26Å; S7-I9 PolarHBondContact O-N 3.41Å; S7-I9 WeakPolarHBondContact OG-CG2 3.19Å; I9-N11 PolarHBondContact O-N 3.47Å; I9-Y15 HydrophobicContact CD1-CD1 4.34Å; I9-Y15 HydrophobicContact CD1-CD2 3.88Å; I9-Y15 HydrophobicContact CD1-CE1 4.33Å; I9-Y15 HydrophobicContact CD1-CE2 3.86Å; I9-Y15 HydrophobicContact CD1-CG 4.11Å; I9-Y147 HydrophobicContact CD1-CD1 4.43Å; I9-Y147 HydrophobicContact CD1-CE1 3.99Å; I9-L195 HydrophobicContact CG2-CB 3.82Å; I9-L195 HydrophobicContact CG2-CD1 3.93Å
10T89.7Confident86.4Confident80 Ų8071.8 Ų71.849%0.49139%0.387SS..G310 helixtrans-74.1-13.9176.8660000113.1S7 L8 N193S7-T10 PolarHBondContact O-N 3.16Å; S7-T10 VanDerWaalsContact O-N 3.15Å; S7-T10 PolarHBondContact O-OG1 3.14Å; L8-T10 PolarHBondContact O-N 2.99Å; T10-N193 WeakPolarHBondContact CG2-ND2 3.24Å
11N91.1Very high87Confident75 Ų7568.6 Ų68.640%0.40137%0.37SS..SBendtrans-118.889.7172.9-174-21000109.7L8 I9 G13 R14 Y15 C248L8-N11 CarbonylContact O-C 3.55Å; L8-N11 PolarHBondContact O-N 2.8Å; I9-N11 PolarHBondContact O-N 3.47Å; N11-G13 VanDerWaalsContact C-N 3.34Å; N11-G13 PolarHBondContact O-N 2.92Å; N11-R14 HydrophobicContact CB-CB 4.11Å; N11-R14 PolarHBondContact O-N 3.28Å; N11-R14 PolarHBondContact OD1-N 3.1Å; N11-Y15 WeakPolarHBondContact O-CB 3.42Å; N11-Y15 PolarHBondContact O-N 2.99Å; N11-C248 VanDerWaalsContact CB-SG 3.54Å
12H87.4Confident89.5Confident95 Ų9557.3 Ų57.344%0.4431%0.314SS..Hα-helixtrans-55.2-44.4-174.9-174.163.5000113.7R14 Y15 V16 E93H12-R14 PolarHBondContact O-N 3.26Å; H12-Y15 PolarHBondContact O-N 3.2Å; H12-V16 WeakPolarHBondContact O-CG2 3.47Å; H12-V16 PolarHBondContact O-N 3.24Å; H12-E93 IonicContact NE2-OE2 2.63Å
13G90.8Very high91.3Very high40 Ų4055.5 Ų55.541%0.41229%0.293SS..Hα-helixtrans-62.4-43.8-179.700000112.2N11 V16 E17N11-G13 VanDerWaalsContact C-N 3.34Å; N11-G13 PolarHBondContact O-N 2.92Å; G13-V16 PolarHBondContact O-N 3.45Å; G13-E17 WeakPolarHBondContact O-CG 3.31Å; G13-E17 PolarHBondContact O-N 3.34Å
14R94.4Very high92.7Very high48 Ų4859.3 Ų59.318%0.18130%0.3CS..Hα-helixtrans-69.2-39178-166.6167.2-175.288.18112.3L8 N11 H12 V16 E17 S18 D242 E249L8-R14 HydrophobicContact CD1-CB 4.3Å; L8-R14 HydrophobicContact CD1-CG 4.02Å; N11-R14 HydrophobicContact CB-CB 4.11Å; N11-R14 PolarHBondContact O-N 3.28Å; N11-R14 PolarHBondContact OD1-N 3.1Å; H12-R14 PolarHBondContact O-N 3.26Å; R14-V16 PolarHBondContact O-N 2.9Å; R14-E17 PolarHBondContact O-N 3.02Å; R14-S18 WeakPolarHBondContact O-CB 3.48Å; R14-S18 PolarHBondContact O-N 2.98Å; R14-S18 PolarHBondContact O-OG 2.8Å; R14-D242 IonicContact CZ-OD2 3.93Å; R14-D242 IonicContact NE-OD2 3.81Å; R14-D242 PolarHBondContact NE-OD2 3.05Å; R14-D242 IonicContact NH2-OD2 2.75Å; R14-D242 PolarHBondContact NH2-OD2 3.2Å; R14-E249 VanDerWaalsContact CZ-CG 3.45Å
15Y92.2Very high93.2Very high33 Ų3357.6 Ų57.613%0.12928%0.28CS..Hα-helixtrans-56.8-48.6172.5171.2-94.6000111.5L8 I9 N11 H12 E17 S18 F19 Y147L8-Y15 HydrophobicContact CD2-CD2 4.05Å; L8-Y15 HydrophobicContact CG-CD2 4.04Å; I9-Y15 HydrophobicContact CD1-CD1 4.34Å; I9-Y15 HydrophobicContact CD1-CD2 3.88Å; I9-Y15 HydrophobicContact CD1-CE1 4.33Å; I9-Y15 HydrophobicContact CD1-CE2 3.86Å; I9-Y15 HydrophobicContact CD1-CG 4.11Å; N11-Y15 WeakPolarHBondContact O-CB 3.42Å; N11-Y15 PolarHBondContact O-N 2.99Å; H12-Y15 PolarHBondContact O-N 3.2Å; Y15-E17 PolarHBondContact O-N 3.45Å; Y15-S18 PolarHBondContact O-N 2.99Å; Y15-F19 VanDerWaalsContact O-CB 3.27Å; Y15-F19 WeakPolarHBondContact O-CB 3.45Å; Y15-F19 PolarHBondContact O-N 3.4Å; Y15-Y147 PolarHBondContact OH-OH 3.3Å
16V90.4Very high93.4Very high52 Ų5256.4 Ų56.432%0.31528%0.276SS..Hα-helixtrans-62.2-42.1178.6170.60000111.4H12 G13 R14 R20H12-V16 WeakPolarHBondContact O-CG2 3.47Å; H12-V16 PolarHBondContact O-N 3.24Å; G13-V16 PolarHBondContact O-N 3.45Å; R14-V16 PolarHBondContact O-N 2.9Å; V16-R20 WeakPolarHBondContact O-CB 3.37Å; V16-R20 PolarHBondContact O-N 3.42Å
17E94.4Very high93.6Very high97 Ų9751.4 Ų51.445%0.45326%0.256SS..Hα-helixtrans-61.3-50.8175.5-74.7178.8172.600112G13 R14 Y15 R20 I21 L239G13-E17 WeakPolarHBondContact O-CG 3.31Å; G13-E17 PolarHBondContact O-N 3.34Å; R14-E17 PolarHBondContact O-N 3.02Å; Y15-E17 PolarHBondContact O-N 3.45Å; E17-R20 PolarHBondContact O-N 2.96Å; E17-I21 WeakPolarHBondContact O-CG1 3.47Å; E17-I21 PolarHBondContact O-N 2.93Å; E17-I21 VanDerWaalsContact O-N 3.07Å; E17-L239 HydrophobicContact CB-CD1 4.47Å; E17-L239 HydrophobicContact CB-CD2 4.18Å
18S96.3Very high93.7Very high0 Ų051.4 Ų51.40%026%0.255CS..Hα-helixtrans-58.8-46.8177.1-77.60000112.2R14 Y15 R20 I21 F22 L239R14-S18 WeakPolarHBondContact O-CB 3.48Å; R14-S18 PolarHBondContact O-N 2.98Å; R14-S18 PolarHBondContact O-OG 2.8Å; Y15-S18 PolarHBondContact O-N 2.99Å; S18-R20 VanDerWaalsContact C-N 3.33Å; S18-R20 PolarHBondContact O-N 3.45Å; S18-I21 PolarHBondContact O-N 3.33Å; S18-F22 PolarHBondContact O-N 3.4Å; S18-L239 WeakPolarHBondContact CB-O 3.23Å; S18-L239 PolarHBondContact OG-O 2.74Å
19F93.3Very high93.8Very high63 Ų6354.2 Ų54.228%0.27627%0.269SS..Hα-helixtrans-60.2-41.3177.5179.1-112.7000112.1Y15 I21 F22 L23 F243Y15-F19 VanDerWaalsContact O-CB 3.27Å; Y15-F19 WeakPolarHBondContact O-CB 3.45Å; Y15-F19 PolarHBondContact O-N 3.4Å; F19-I21 PolarHBondContact O-N 3.42Å; F19-F22 AromaticContact CD2-CD1 3.89Å; F19-F22 HydrophobicContact CD2-CD1 3.89Å; F19-F22 HydrophobicContact CD2-CE1 4.44Å; F19-F22 AromaticContact CE2-CD1 3.99Å; F19-F22 HydrophobicContact CE2-CD1 3.99Å; F19-F22 HydrophobicContact CE2-CE1 4.13Å; F19-F22 WeakPolarHBondContact O-CB 3.14Å; F19-F22 PolarHBondContact O-N 2.83Å; F19-L23 HydrophobicContact CD1-CD1 4.09Å; F19-L23 HydrophobicContact CE1-CD1 3.46Å; F19-L23 VanDerWaalsContact CE1-CD1 3.46Å; F19-L23 HydrophobicContact CE1-CG 4.13Å; F19-L23 HydrophobicContact CE2-CD1 4.3Å; F19-L23 HydrophobicContact CE2-CD2 4.18Å; F19-L23 HydrophobicContact CE2-CG 4.12Å; F19-L23 HydrophobicContact CZ-CD1 3.58Å; F19-L23 HydrophobicContact CZ-CD2 4.05Å; F19-L23 HydrophobicContact CZ-CG 3.9Å; F19-L23 WeakPolarHBondContact O-CG 3.48Å; F19-L23 PolarHBondContact O-N 3.2Å; F19-F243 HydrophobicContact CB-CE2 4.39Å; F19-F243 HydrophobicContact CD2-CE2 4.04Å; F19-F243 HydrophobicContact CD2-CZ 4.22Å
20R93.1Very high94.2Very high163 Ų16357.4 Ų57.462%0.61528%0.282SS*.Hα-helixtrans-63.9-41.3176-173-174.467.2163.7-1.1112.1V16 E17 S18 F22 K24V16-R20 WeakPolarHBondContact O-CB 3.37Å; V16-R20 PolarHBondContact O-N 3.42Å; E17-R20 PolarHBondContact O-N 2.96Å; S18-R20 VanDerWaalsContact C-N 3.33Å; S18-R20 PolarHBondContact O-N 3.45Å; R20-F22 VanDerWaalsContact C-N 3.35Å; R20-K24 WeakPolarHBondContact O-CB 3.44Å; R20-K24 PolarHBondContact O-N 3.22Å; R20-K24 VanDerWaalsContact O-N 3.1Å
21I97.4Very high94.5Very high6 Ų653.8 Ų53.83%0.03126%0.261CS..Hα-helixtrans-67.8-38.4176.1-59.3-53.4000110.4E17 S18 F19 K24 N25 D236 L239 L240E17-I21 WeakPolarHBondContact O-CG1 3.47Å; E17-I21 PolarHBondContact O-N 2.93Å; E17-I21 VanDerWaalsContact O-N 3.07Å; S18-I21 PolarHBondContact O-N 3.33Å; F19-I21 PolarHBondContact O-N 3.42Å; I21-K24 PolarHBondContact O-N 2.91Å; I21-N25 WeakPolarHBondContact CG2-ND2 3.32Å; I21-N25 WeakPolarHBondContact O-CB 3.32Å; I21-N25 PolarHBondContact O-N 2.87Å; I21-N25 PolarHBondContact O-ND2 3.25Å; I21-D236 HydrophobicContact CG2-CB 3.89Å; I21-L239 HydrophobicContact CB-CB 4.49Å; I21-L239 HydrophobicContact CG1-CB 4.27Å; I21-L239 HydrophobicContact CG1-CD1 3.72Å; I21-L240 HydrophobicContact CB-CD2 4.27Å; I21-L240 HydrophobicContact CG2-CD1 4.28Å; I21-L240 HydrophobicContact CG2-CD2 3.71Å; I21-L240 HydrophobicContact CG2-CG 3.75Å
22F97.4Very high94.8Very high6 Ų650.3 Ų50.33%0.02624%0.242CC..Hα-helixtrans-55-56.4172.1156.4-107.3000111.2S18 F19 R20 K24 N25 S26 E28 M224 L240 F243S18-F22 PolarHBondContact O-N 3.4Å; F19-F22 AromaticContact CD2-CD1 3.89Å; F19-F22 HydrophobicContact CD2-CD1 3.89Å; F19-F22 HydrophobicContact CD2-CE1 4.44Å; F19-F22 AromaticContact CE2-CD1 3.99Å; F19-F22 HydrophobicContact CE2-CD1 3.99Å; F19-F22 HydrophobicContact CE2-CE1 4.13Å; F19-F22 WeakPolarHBondContact O-CB 3.14Å; F19-F22 PolarHBondContact O-N 2.83Å; R20-F22 VanDerWaalsContact C-N 3.35Å; F22-K24 VanDerWaalsContact C-N 3.26Å; F22-K24 PolarHBondContact O-N 2.85Å; F22-N25 CarbonylContact O-C 3.59Å; F22-N25 PolarHBondContact O-N 3.35Å; F22-S26 WeakPolarHBondContact O-CB 3.49Å; F22-S26 PolarHBondContact O-N 3.33Å; F22-S26 PolarHBondContact O-OG 3.35Å; F22-E28 HydrophobicContact CE1-CB 4.15Å; F22-E28 HydrophobicContact CE1-CG 3.85Å; F22-E28 HydrophobicContact CZ-CB 3.86Å; F22-E28 HydrophobicContact CZ-CG 3.79Å; F22-E28 WeakPolarHBondContact CZ-OE2 3.48Å; F22-M224 HydrophobicContact CB-CE 4.44Å; F22-M224 HydrophobicContact CD2-CE 4.02Å; F22-M224 HydrophobicContact CD2-CG 4.19Å; F22-M224 HydrophobicContact CD2-SD 3.82Å; F22-M224 HydrophobicContact CE2-SD 4.28Å; F22-L240 HydrophobicContact CB-CD2 4.33Å; F22-F243 HydrophobicContact CB-CD1 3.8Å; F22-F243 HydrophobicContact CB-CE1 3.8Å; F22-F243 HydrophobicContact CB-CG 4.18Å; F22-F243 HydrophobicContact CB-CZ 4.18Å; F22-F243 AromaticContact CD1-CE1 3.78Å; F22-F243 HydrophobicContact CD1-CE1 3.78Å; F22-F243 AromaticContact CD1-CZ 3.72Å; F22-F243 HydrophobicContact CD1-CZ 3.72Å; F22-F243 AromaticContact CD2-CD1 3.97Å; F22-F243 HydrophobicContact CD2-CD1 3.97Å; F22-F243 AromaticContact CD2-CE1 3.52Å; F22-F243 HydrophobicContact CD2-CE1 3.52Å; F22-F243 HydrophobicContact CD2-CZ 4.32Å; F22-F243 HydrophobicContact CE1-CE1 4.21Å; F22-F243 HydrophobicContact CE1-CZ 4.15Å; F22-F243 AromaticContact CE2-CE1 3.97Å; F22-F243 HydrophobicContact CE2-CE1 3.97Å; F22-F243 AromaticContact CG-CD1 3.88Å; F22-F243 HydrophobicContact CG-CD1 3.88Å; F22-F243 AromaticContact CG-CE1 3.4Å; F22-F243 HydrophobicContact CG-CE1 3.4Å; F22-F243 AromaticContact CG-CZ 3.8Å; F22-F243 HydrophobicContact CG-CZ 3.8Å; F22-F243 HydrophobicContact CZ-CE1 4.28Å
23L94.4Very high95.3Very high44 Ų4449.7 Ų49.723%0.2324%0.239CC..Hα-helixtrans-58.9-37.1-179.3-69.3-179.7000112.8F19 N25 E28F19-L23 HydrophobicContact CD1-CD1 4.09Å; F19-L23 HydrophobicContact CE1-CD1 3.46Å; F19-L23 VanDerWaalsContact CE1-CD1 3.46Å; F19-L23 HydrophobicContact CE1-CG 4.13Å; F19-L23 HydrophobicContact CE2-CD1 4.3Å; F19-L23 HydrophobicContact CE2-CD2 4.18Å; F19-L23 HydrophobicContact CE2-CG 4.12Å; F19-L23 HydrophobicContact CZ-CD1 3.58Å; F19-L23 HydrophobicContact CZ-CD2 4.05Å; F19-L23 HydrophobicContact CZ-CG 3.9Å; F19-L23 WeakPolarHBondContact O-CG 3.48Å; F19-L23 PolarHBondContact O-N 3.2Å; L23-N25 VanDerWaalsContact C-N 3.29Å; L23-N25 PolarHBondContact O-N 2.94Å; L23-E28 HydrophobicContact CD2-CB 4.01Å; L23-E28 HydrophobicContact CD2-CG 3.82Å
24K96.3Very high95.6Very high152 Ų15251.8 Ų51.866%0.66124%0.238SC*.Hα-helixtrans-68-29.7177.7-178.3-174.9169.1-159.10112.6R20 I21 F22R20-K24 WeakPolarHBondContact O-CB 3.44Å; R20-K24 PolarHBondContact O-N 3.22Å; R20-K24 VanDerWaalsContact O-N 3.1Å; I21-K24 PolarHBondContact O-N 2.91Å; F22-K24 VanDerWaalsContact C-N 3.26Å; F22-K24 PolarHBondContact O-N 2.85Å
25N97.4Very high95.8Very high42 Ų4249.9 Ų49.923%0.22523%0.231CC..Hα-helixtrans-107.49.2-174.7-68.6-83.1000112.9I21 F22 L23 M224 D225 L240I21-N25 WeakPolarHBondContact CG2-ND2 3.32Å; I21-N25 WeakPolarHBondContact O-CB 3.32Å; I21-N25 PolarHBondContact O-N 2.87Å; I21-N25 PolarHBondContact O-ND2 3.25Å; F22-N25 CarbonylContact O-C 3.59Å; F22-N25 PolarHBondContact O-N 3.35Å; L23-N25 VanDerWaalsContact C-N 3.29Å; L23-N25 PolarHBondContact O-N 2.94Å; N25-M224 CarbonylContact O-C 3.28Å; N25-M224 WeakPolarHBondContact O-CA 3.47Å; N25-D225 PolarHBondContact O-N 3.27Å; N25-L240 HydrophobicContact CB-CD1 4.4Å
26S97.8Very high96.1Very high19 Ų1948.5 Ų48.513%0.13323%0.226CC..BIsolated β-bridgetrans-127162.6179.272.80000112.3F22 E28 H223F22-S26 WeakPolarHBondContact O-CB 3.49Å; F22-S26 PolarHBondContact O-N 3.33Å; F22-S26 PolarHBondContact O-OG 3.35Å; S26-E28 PolarHBondContact O-N 3.34Å; S26-E28 VanDerWaalsContact OG-CB 3.24Å; S26-E28 WeakPolarHBondContact OG-CB 3.48Å; S26-E28 PolarHBondContact OG-N 3.42Å; S26-H223 CarbonylContact C-O 3.56Å; S26-H223 WeakPolarHBondContact CA-O 3.43Å; S26-H223 WeakPolarHBondContact CB-O 3.39Å
27T97.4Very high96.4Very high18 Ų1850.3 Ų50.311%0.1123%0.231CC..SBendtrans-89.523170.656.10000112.6Q30 C31 S222 H223T27-Q30 PolarHBondContact O-N 2.8Å; T27-C31 PolarHBondContact O-N 3.02Å; T27-S222 VanDerWaalsContact OG1-CA 3.3Å; T27-S222 WeakPolarHBondContact OG1-CA 3.48Å; T27-S222 PolarHBondContact OG1-OG 2.92Å; T27-H223 WeakPolarHBondContact CG2-CE1 3.45Å; T27-H223 PolarHBondContact N-O 3.38Å; T27-H223 PolarHBondContact OG1-N 3.35Å; T27-H223 PolarHBondContact OG1-O 3.03Å
28E95.9Very high96.6Very high6 Ų652.1 Ų52.13%0.02824%0.24CC..Hα-helixtrans-51.8-61.6-175.5-178.770.3-174.400112.8F22 L23 S26 Q30 C31 M32 Q143 N283F22-E28 HydrophobicContact CE1-CB 4.15Å; F22-E28 HydrophobicContact CE1-CG 3.85Å; F22-E28 HydrophobicContact CZ-CB 3.86Å; F22-E28 HydrophobicContact CZ-CG 3.79Å; F22-E28 WeakPolarHBondContact CZ-OE2 3.48Å; L23-E28 HydrophobicContact CD2-CB 4.01Å; L23-E28 HydrophobicContact CD2-CG 3.82Å; S26-E28 PolarHBondContact O-N 3.34Å; S26-E28 VanDerWaalsContact OG-CB 3.24Å; S26-E28 WeakPolarHBondContact OG-CB 3.48Å; S26-E28 PolarHBondContact OG-N 3.42Å; E28-Q30 VanDerWaalsContact C-N 3.29Å; E28-Q30 PolarHBondContact O-N 2.84Å; E28-C31 PolarHBondContact O-SG 2.78Å; E28-M32 HydrophobicContact CG-CE 3.99Å; E28-M32 WeakPolarHBondContact O-CG 3.27Å; E28-M32 PolarHBondContact O-N 2.84Å; E28-M32 WeakPolarHBondContact OE1-CE 3.46Å; E28-Q143 WeakPolarHBondContact OE1-CG 2.95Å; E28-Q143 PolarHBondContact OE1-NE2 3.19Å; E28-N283 PolarHBondContact OE2-ND2 3.31Å
29H93.8Very high96.6Very high60 Ų6056 Ų5628%0.27826%0.258SS..Hα-helixtrans-71.5-27.2180-70.8177.9000112.2Q33 E65H29-Q33 VanDerWaalsContact O-CB 3.28Å; H29-Q33 WeakPolarHBondContact O-CB 3.35Å; H29-Q33 PolarHBondContact O-N 2.79Å; H29-E65 IonicContact CE1-OE2 3.78Å; H29-E65 PolarHBondContact CE1-OE2 2.6Å; H29-E65 IonicContact ND1-OE2 3.84Å; H29-E65 PolarHBondContact ND1-OE2 2.8Å
30Q96.4Very high96.9Very high106 Ų10653 Ų5350%0.49525%0.245SC..Hα-helixtrans-64.7-50.5177.4-177.3-171.8-21.800111T27 E28 M32 Q33 E34T27-Q30 PolarHBondContact O-N 2.8Å; E28-Q30 VanDerWaalsContact C-N 3.29Å; E28-Q30 PolarHBondContact O-N 2.84Å; Q30-M32 VanDerWaalsContact C-N 3.32Å; Q30-M32 PolarHBondContact O-N 2.85Å; Q30-Q33 WeakPolarHBondContact O-CB 3.38Å; Q30-Q33 PolarHBondContact O-N 3.46Å; Q30-Q33 VanDerWaalsContact O-N 3.16Å; Q30-E34 PolarHBondContact NE2-OE1 3.02Å; Q30-E34 WeakPolarHBondContact O-CG 3.22Å; Q30-E34 PolarHBondContact O-N 3.42Å
31C97Very high97.1Very high5 Ų547.6 Ų47.63%0.03423%0.23CC..Hα-helixtrans-66.8-35.5-178.3730000111.6T27 E28 E34 F35 L220 P221 L285T27-C31 PolarHBondContact O-N 3.02Å; E28-C31 PolarHBondContact O-SG 2.78Å; C31-E34 PolarHBondContact O-N 2.72Å; C31-F35 PolarHBondContact O-N 2.9Å; C31-F35 VanDerWaalsContact O-N 3.09Å; C31-L220 HydrophobicContact CB-CB 4.25Å; C31-P221 WeakPolarHBondContact CB-O 3.3Å; C31-L285 VanDerWaalsContact SG-CD1 3.54Å
32M97.2Very high97.2Very high2 Ų249.7 Ų49.71%0.0125%0.254CS..Hα-helixtrans-62.7-44171.7-68.3-174.9-162.300111.6E28 Q30 E34 F35 I36 I66 V142 Q143 I171 L285E28-M32 HydrophobicContact CG-CE 3.99Å; E28-M32 WeakPolarHBondContact O-CG 3.27Å; E28-M32 PolarHBondContact O-N 2.84Å; E28-M32 WeakPolarHBondContact OE1-CE 3.46Å; Q30-M32 VanDerWaalsContact C-N 3.32Å; Q30-M32 PolarHBondContact O-N 2.85Å; M32-E34 VanDerWaalsContact C-N 3.35Å; M32-E34 PolarHBondContact O-N 2.75Å; M32-F35 PolarHBondContact O-N 2.93Å; M32-I36 WeakPolarHBondContact O-CB 3.34Å; M32-I36 WeakPolarHBondContact O-CD1 3.49Å; M32-I36 WeakPolarHBondContact O-CG1 3.19Å; M32-I36 PolarHBondContact O-N 2.6Å; M32-I66 HydrophobicContact CB-CD1 3.95Å; M32-I66 HydrophobicContact SD-CD1 3.8Å; M32-I66 HydrophobicContact SD-CG1 3.87Å; M32-V142 HydrophobicContact CE-CG1 4.09Å; M32-V142 HydrophobicContact SD-CG1 3.89Å; M32-Q143 HydrophobicContact CE-CG 3.62Å; M32-I171 HydrophobicContact CE-CG2 4.12Å; M32-I171 HydrophobicContact CG-CD1 4.38Å; M32-I171 HydrophobicContact SD-CD1 4.48Å; M32-L285 HydrophobicContact CE-CD1 3.52Å; M32-L285 HydrophobicContact CG-CD1 4.06Å
33Q97.3Very high97.2Very high81 Ų8149.9 Ų49.938%0.37926%0.256SS..Hα-helixtrans-60.9-44177.1-178.9178.6-2000111.4H29 Q30 F35 I36 E37 L69H29-Q33 VanDerWaalsContact O-CB 3.28Å; H29-Q33 WeakPolarHBondContact O-CB 3.35Å; H29-Q33 PolarHBondContact O-N 2.79Å; Q30-Q33 WeakPolarHBondContact O-CB 3.38Å; Q30-Q33 PolarHBondContact O-N 3.46Å; Q30-Q33 VanDerWaalsContact O-N 3.16Å; Q33-F35 VanDerWaalsContact C-N 3.35Å; Q33-F35 PolarHBondContact O-N 2.88Å; Q33-I36 PolarHBondContact O-N 2.95Å; Q33-I36 VanDerWaalsContact O-N 3.15Å; Q33-E37 HydrophobicContact CG-CG 4.34Å; Q33-E37 WeakPolarHBondContact CG-OE1 3.46Å; Q33-E37 PolarHBondContact NE2-OE1 2.91Å; Q33-E37 WeakPolarHBondContact O-CB 3.13Å; Q33-E37 WeakPolarHBondContact O-CG 3.35Å; Q33-E37 PolarHBondContact O-N 3.09Å; Q33-L69 HydrophobicContact CB-CD1 4.29Å; Q33-L69 HydrophobicContact CG-CD1 4.29Å
34E97.9Very high97.4Very high84 Ų8447.8 Ų47.839%0.39325%0.245SC..Hα-helixtrans-58.8-44.7176.6-72.7173.9-164.800111.6Q30 C31 M32 E37 Q38Q30-E34 PolarHBondContact NE2-OE1 3.02Å; Q30-E34 WeakPolarHBondContact O-CG 3.22Å; Q30-E34 PolarHBondContact O-N 3.42Å; C31-E34 PolarHBondContact O-N 2.72Å; M32-E34 VanDerWaalsContact C-N 3.35Å; M32-E34 PolarHBondContact O-N 2.75Å; E34-E37 PolarHBondContact O-N 3.31Å; E34-Q38 WeakPolarHBondContact O-CB 3.17Å; E34-Q38 WeakPolarHBondContact O-CG 3.43Å; E34-Q38 PolarHBondContact O-N 3.37Å
35F98.4Very high97.4Very high9 Ų942.9 Ų42.94%0.03923%0.23CC..Hα-helixtrans-60.9-45.4173.4172.6-89.8000112.1C31 M32 Q33 E37 Q38 Q39 L40 V43 L169 Y218 L220 V287C31-F35 PolarHBondContact O-N 2.9Å; C31-F35 VanDerWaalsContact O-N 3.09Å; M32-F35 PolarHBondContact O-N 2.93Å; Q33-F35 VanDerWaalsContact C-N 3.35Å; Q33-F35 PolarHBondContact O-N 2.88Å; F35-E37 VanDerWaalsContact C-N 3.27Å; F35-E37 PolarHBondContact O-N 2.87Å; F35-Q38 PolarHBondContact O-N 3.27Å; F35-Q39 HydrophobicContact CD2-CB 3.61Å; F35-Q39 HydrophobicContact CD2-CG 3.91Å; F35-Q39 HydrophobicContact CE2-CB 3.5Å; F35-Q39 HydrophobicContact CE2-CG 4.17Å; F35-Q39 HydrophobicContact CG-CB 4.31Å; F35-Q39 HydrophobicContact CZ-CB 4.11Å; F35-Q39 WeakPolarHBondContact O-CA 3.29Å; F35-Q39 WeakPolarHBondContact O-CB 3.49Å; F35-Q39 PolarHBondContact O-N 2.84Å; F35-L40 HydrophobicContact CE1-CB 4.13Å; F35-L40 HydrophobicContact CE1-CD1 4.24Å; F35-L40 PolarHBondContact O-N 3.45Å; F35-V43 HydrophobicContact CZ-CG2 4.39Å; F35-L169 HydrophobicContact CE1-CD1 3.86Å; F35-L169 HydrophobicContact CZ-CD1 4.22Å; F35-Y218 HydrophobicContact CD2-CG 4.44Å; F35-Y218 HydrophobicContact CE2-CD1 4.09Å; F35-Y218 AromaticContact CE2-CD2 3.9Å; F35-Y218 HydrophobicContact CE2-CD2 3.9Å; F35-Y218 HydrophobicContact CE2-CE1 4.5Å; F35-Y218 HydrophobicContact CE2-CE2 4.34Å; F35-Y218 AromaticContact CE2-CG 3.76Å; F35-Y218 HydrophobicContact CE2-CG 3.76Å; F35-Y218 HydrophobicContact CZ-CD2 4.5Å; F35-L220 HydrophobicContact CB-CD2 3.78Å; F35-L220 HydrophobicContact CB-CG 4.2Å; F35-L220 HydrophobicContact CD2-CD1 4.2Å; F35-L220 HydrophobicContact CG-CD2 4.35Å; F35-V287 HydrophobicContact CD1-CG2 3.99Å; F35-V287 HydrophobicContact CD2-CB 4.29Å; F35-V287 HydrophobicContact CD2-CG2 3.92Å; F35-V287 HydrophobicContact CE1-CB 4.43Å; F35-V287 HydrophobicContact CE1-CG1 3.84Å; F35-V287 HydrophobicContact CE1-CG2 4.14Å; F35-V287 HydrophobicContact CE2-CB 3.95Å; F35-V287 HydrophobicContact CE2-CG1 3.93Å; F35-V287 HydrophobicContact CE2-CG2 4.05Å; F35-V287 HydrophobicContact CG-CG2 3.9Å; F35-V287 HydrophobicContact CZ-CB 4.04Å; F35-V287 HydrophobicContact CZ-CG1 3.51Å; F35-V287 HydrophobicContact CZ-CG2 4.17Å
36I98.4Very high97.4Very high3 Ų342.2 Ų42.22%0.01523%0.228CC..Hα-helixtrans-63.8-34.6-179.7-69.4163.8000111.3M32 Q33 L40 P41 I66 L69 M70 K73M32-I36 WeakPolarHBondContact O-CB 3.34Å; M32-I36 WeakPolarHBondContact O-CD1 3.49Å; M32-I36 WeakPolarHBondContact O-CG1 3.19Å; M32-I36 PolarHBondContact O-N 2.6Å; Q33-I36 PolarHBondContact O-N 2.95Å; Q33-I36 VanDerWaalsContact O-N 3.15Å; I36-L40 HydrophobicContact CB-CD2 4.39Å; I36-L40 HydrophobicContact CG1-CD2 4.26Å; I36-L40 HydrophobicContact CG2-CD2 3.89Å; I36-P41 WeakPolarHBondContact O-CD 3.37Å; I36-I66 HydrophobicContact CD1-CG2 3.86Å; I36-L69 HydrophobicContact CD1-CB 4.04Å; I36-L69 HydrophobicContact CD1-CD1 4.42Å; I36-L69 HydrophobicContact CG2-CB 4.06Å; I36-M70 HydrophobicContact CD1-CG 3.9Å; I36-M70 HydrophobicContact CG1-CG 4.05Å; I36-K73 HydrophobicContact CG2-CD 4.46Å; I36-K73 HydrophobicContact CG2-CG 3.69Å; I36-K73 WeakPolarHBondContact O-CE 3.33Å; I36-K73 WeakPolarHBondContact O-CG 3.21Å
37E97.6Very high97.4Very high91 Ų9141.3 Ų41.343%0.42522%0.222SC..Hα-helixtrans-76-41.8178.2-73.4178-178.800112.7Q33 E34 F35Q33-E37 HydrophobicContact CG-CG 4.34Å; Q33-E37 WeakPolarHBondContact CG-OE1 3.46Å; Q33-E37 PolarHBondContact NE2-OE1 2.91Å; Q33-E37 WeakPolarHBondContact O-CB 3.13Å; Q33-E37 WeakPolarHBondContact O-CG 3.35Å; Q33-E37 PolarHBondContact O-N 3.09Å; E34-E37 PolarHBondContact O-N 3.31Å; F35-E37 VanDerWaalsContact C-N 3.27Å; F35-E37 PolarHBondContact O-N 2.87Å
38Q97.1Very high97.4Very high134 Ų13440.6 Ų40.663%0.62622%0.218SC*.Hα-helixtrans-98.4-37.5-167.7-61.2178.818.500113.8E34 F35E34-Q38 WeakPolarHBondContact O-CB 3.17Å; E34-Q38 WeakPolarHBondContact O-CG 3.43Å; E34-Q38 PolarHBondContact O-N 3.37Å; F35-Q38 PolarHBondContact O-N 3.27Å
39Q98.1Very high97.3Very high82 Ų8243.9 Ų43.938%0.38324%0.236SC..THydrogen-bonded Turntrans-110.8-40.9-168.6-56.8-58.6-31.400112.6F35 P41 G42 V43 Y218F35-Q39 HydrophobicContact CD2-CB 3.61Å; F35-Q39 HydrophobicContact CD2-CG 3.91Å; F35-Q39 HydrophobicContact CE2-CB 3.5Å; F35-Q39 HydrophobicContact CE2-CG 4.17Å; F35-Q39 HydrophobicContact CG-CB 4.31Å; F35-Q39 HydrophobicContact CZ-CB 4.11Å; F35-Q39 WeakPolarHBondContact O-CA 3.29Å; F35-Q39 WeakPolarHBondContact O-CB 3.49Å; F35-Q39 PolarHBondContact O-N 2.84Å; Q39-P41 VanDerWaalsContact C-N 3.34Å; Q39-G42 PolarHBondContact O-N 3.09Å; Q39-V43 PolarHBondContact O-N 3.41Å; Q39-Y218 HydrophobicContact CB-CE1 4.49Å; Q39-Y218 HydrophobicContact CG-CD1 4.48Å
40L98.4Very high97.2Very high0 Ų045.6 Ų45.60%027%0.269CS..Hα-helixtrans-54.4-39.9-177.3-174.271.7000113.8F35 I36 G42 V43 I44 M70 K73 F138 L169F35-L40 HydrophobicContact CE1-CB 4.13Å; F35-L40 HydrophobicContact CE1-CD1 4.24Å; F35-L40 PolarHBondContact O-N 3.45Å; I36-L40 HydrophobicContact CB-CD2 4.39Å; I36-L40 HydrophobicContact CG1-CD2 4.26Å; I36-L40 HydrophobicContact CG2-CD2 3.89Å; L40-G42 PolarHBondContact O-N 3.09Å; L40-G42 VanDerWaalsContact O-N 3.15Å; L40-V43 HydrophobicContact CD1-CB 4.34Å; L40-V43 HydrophobicContact CD1-CG1 4.41Å; L40-V43 WeakPolarHBondContact O-CA 3.28Å; L40-V43 WeakPolarHBondContact O-CB 3.48Å; L40-V43 PolarHBondContact O-N 3.09Å; L40-I44 HydrophobicContact CD1-CG2 3.73Å; L40-I44 HydrophobicContact CG-CD1 4.32Å; L40-I44 HydrophobicContact CG-CG2 4.01Å; L40-I44 WeakPolarHBondContact O-CG1 3.19Å; L40-I44 PolarHBondContact O-N 3.36Å; L40-M70 HydrophobicContact CD2-CB 3.92Å; L40-M70 HydrophobicContact CD2-CG 3.67Å; L40-K73 HydrophobicContact CD2-CB 4.18Å; L40-K73 HydrophobicContact CD2-CG 4.21Å; L40-F138 HydrophobicContact CD1-CZ 4.15Å; L40-L169 HydrophobicContact CD1-CD1 3.94Å
41P98.3Very high97.2Very high49 Ų4943.1 Ų43.132%0.31826%0.257SS..Hα-helixtrans-56.4-32.4178.2-27.236.7000114I36 Q39 S45I36-P41 WeakPolarHBondContact O-CD 3.37Å; Q39-P41 VanDerWaalsContact C-N 3.34Å; P41-S45 WeakPolarHBondContact O-CB 3.33Å; P41-S45 PolarHBondContact O-N 2.97Å
42G98.1Very high97.1Very high51 Ų5147.7 Ų47.753%0.52629%0.289SS..Hα-helixtrans-71.7-44.7173.200000112.2Q39 L40 I44 S45Q39-G42 PolarHBondContact O-N 3.09Å; L40-G42 PolarHBondContact O-N 3.09Å; L40-G42 VanDerWaalsContact O-N 3.15Å; G42-I44 PolarHBondContact O-N 3.36Å; G42-S45 WeakPolarHBondContact O-CB 3.42Å; G42-S45 PolarHBondContact O-N 2.99Å; G42-S45 PolarHBondContact O-OG 2.98Å
43V98.1Very high97.2Very high10 Ų1049.6 Ų49.66%0.06130%0.3CS..Hα-helixtrans-58.4-47.1178.4172.70000111.7F35 Q39 L40 S45 K167 V289F35-V43 HydrophobicContact CZ-CG2 4.39Å; Q39-V43 PolarHBondContact O-N 3.41Å; L40-V43 HydrophobicContact CD1-CB 4.34Å; L40-V43 HydrophobicContact CD1-CG1 4.41Å; L40-V43 WeakPolarHBondContact O-CA 3.28Å; L40-V43 WeakPolarHBondContact O-CB 3.48Å; L40-V43 PolarHBondContact O-N 3.09Å; V43-S45 VanDerWaalsContact C-N 3.27Å; V43-S45 PolarHBondContact O-N 2.67Å; V43-K167 HydrophobicContact CG1-CB 4.4Å; V43-K167 HydrophobicContact CG1-CG 4.09Å; V43-V289 HydrophobicContact CG1-CG1 3.7Å; V43-V289 HydrophobicContact CG1-CG2 3.97Å; V43-V289 HydrophobicContact CG2-CG2 4.01Å
44I98.2Very high97.2Very high0 Ų045.7 Ų45.70%028%0.282CS..THydrogen-bonded Turntrans-87.48.9-177.469.9-178.3000113L40 G42 S46 I47 K73 V74 Y78 F138L40-I44 HydrophobicContact CD1-CG2 3.73Å; L40-I44 HydrophobicContact CG-CD1 4.32Å; L40-I44 HydrophobicContact CG-CG2 4.01Å; L40-I44 WeakPolarHBondContact O-CG1 3.19Å; L40-I44 PolarHBondContact O-N 3.36Å; G42-I44 PolarHBondContact O-N 3.36Å; I44-S46 PolarHBondContact O-N 3.1Å; I44-S46 VanDerWaalsContact O-N 3.09Å; I44-I47 HydrophobicContact CB-CD1 3.88Å; I44-I47 HydrophobicContact CB-CG1 4.2Å; I44-I47 HydrophobicContact CB-CG2 4.46Å; I44-I47 HydrophobicContact CG2-CD1 4.17Å; I44-I47 WeakPolarHBondContact O-CG1 3.43Å; I44-I47 PolarHBondContact O-N 3.37Å; I44-K73 HydrophobicContact CD1-CB 3.88Å; I44-V74 HydrophobicContact CD1-CB 4.36Å; I44-V74 HydrophobicContact CD1-CG2 3.73Å; I44-Y78 WeakPolarHBondContact O-CE2 3.48Å; I44-Y78 PolarHBondContact O-OH 3.33Å; I44-F138 HydrophobicContact CG2-CD2 4.48Å; I44-F138 HydrophobicContact CG2-CE2 4.35Å
45S97.6Very high97.3Very high49 Ų4943.3 Ų43.334%0.34327%0.272SS..THydrogen-bonded Turntrans-64-20.9-168.763.30000114.6P41 G42 V43 R77 Y78P41-S45 WeakPolarHBondContact O-CB 3.33Å; P41-S45 PolarHBondContact O-N 2.97Å; G42-S45 WeakPolarHBondContact O-CB 3.42Å; G42-S45 PolarHBondContact O-N 2.99Å; G42-S45 PolarHBondContact O-OG 2.98Å; V43-S45 VanDerWaalsContact C-N 3.27Å; V43-S45 PolarHBondContact O-N 2.67Å; S45-R77 PolarHBondContact O-NE 3.01Å; S45-R77 PolarHBondContact O-NH2 3.41Å; S45-Y78 PolarHBondContact O-OH 2.65Å
46S96.7Very high97.3Very high27 Ų2743 Ų4319%0.18927%0.271CS..THydrogen-bonded Turntrans-113.4-11.2-177.560.10000115.6I44 G48 N49 Y78 Q165I44-S46 PolarHBondContact O-N 3.1Å; I44-S46 VanDerWaalsContact O-N 3.09Å; S46-G48 PolarHBondContact O-N 3.28Å; S46-G48 VanDerWaalsContact O-N 3.12Å; S46-N49 PolarHBondContact O-N 3.45Å; S46-Y78 VanDerWaalsContact C-OH 3.22Å; S46-Y78 WeakPolarHBondContact CA-OH 3.09Å; S46-Y78 PolarHBondContact N-OH 2.98Å; S46-Q165 PolarHBondContact O-OE1 3.45Å
47I97.9Very high97.3Very high0 Ų042.8 Ų42.80%027%0.27CS..THydrogen-bonded Turntrans-61.4-29.9-16768.1171.6000113.4I44 I54 V74 Y78 D137 F138 K167I44-I47 HydrophobicContact CB-CD1 3.88Å; I44-I47 HydrophobicContact CB-CG1 4.2Å; I44-I47 HydrophobicContact CB-CG2 4.46Å; I44-I47 HydrophobicContact CG2-CD1 4.17Å; I44-I47 WeakPolarHBondContact O-CG1 3.43Å; I44-I47 PolarHBondContact O-N 3.37Å; I47-I54 HydrophobicContact CD1-CG2 4.15Å; I47-V74 HydrophobicContact CD1-CG2 4.37Å; I47-Y78 HydrophobicContact CG1-CE2 3.8Å; I47-Y78 PolarHBondContact N-OH 3.2Å; I47-D137 HydrophobicContact CB-CB 4.39Å; I47-D137 WeakPolarHBondContact CB-O 3.33Å; I47-D137 WeakPolarHBondContact CG2-O 3.27Å; I47-F138 HydrophobicContact CD1-CB 3.9Å; I47-F138 HydrophobicContact CD1-CG 4.46Å; I47-K167 HydrophobicContact CG2-CG 4.04Å
48G96.3Very high97.4Very high3 Ų338.5 Ų38.53%0.03125%0.25CC..THydrogen-bonded Turntrans-106.39.3-176.800000115.2S46 G50 K51 Y78S46-G48 PolarHBondContact O-N 3.28Å; S46-G48 VanDerWaalsContact O-N 3.12Å; G48-G50 PolarHBondContact O-N 3.35Å; G48-G50 VanDerWaalsContact O-N 3.15Å; G48-K51 PolarHBondContact O-N 3.4Å; G48-K51 VanDerWaalsContact O-N 3.07Å; G48-Y78 VanDerWaalsContact N-CZ 3.32Å; G48-Y78 PolarHBondContact N-OH 2.99Å; G48-Y78 VanDerWaalsContact N-OH 3.09Å
49N94Very high97.5Very high76 Ų7632.1 Ų32.141%0.40622%0.22SC..THydrogen-bonded Turntrans-60.6120.5-174.8-76.5-9.8000111.7S46 K51S46-N49 PolarHBondContact O-N 3.45Å; N49-K51 PolarHBondContact O-N 3.1Å
50G91.8Very high97.5Very high95 Ų9529 Ų2998%0.97921%0.211SC*.THydrogen-bonded Turntrans72.38-179.900000115G48G48-G50 PolarHBondContact O-N 3.35Å; G48-G50 VanDerWaalsContact O-N 3.15Å
51K96.2Very high97.4Very high55 Ų5529.4 Ų29.424%0.23921%0.214CC..  trans-97.5138.1-178.5-61.8-175.2176.6170.90111.4G48 N49 T53 D137G48-K51 PolarHBondContact O-N 3.4Å; G48-K51 VanDerWaalsContact O-N 3.07Å; N49-K51 PolarHBondContact O-N 3.1Å; K51-T53 VanDerWaalsContact C-N 3.33Å; K51-T53 WeakPolarHBondContact CB-O 3.48Å; K51-D137 IonicContact NZ-OD1 2.76Å; K51-D137 PolarHBondContact NZ-OD1 3.07Å
52S96.4Very high97.2Very high100 Ų10027.5 Ų27.570%0.69920%0.204SC*.SBendtrans-83.8-13.3169.555.40000112.6T82S52-T82 PolarHBondContact O-N 3.14Å
53T98.1Very high97.1Very high42 Ų4226 Ų2626%0.25819%0.186SC..EExtended strand (participates in β ladder)trans-144.6136.6178.8-60.40000110K51 T82 N84K51-T53 VanDerWaalsContact C-N 3.33Å; K51-T53 WeakPolarHBondContact CB-O 3.48Å; T53-T82 CarbonylContact C-O 3.54Å; T53-T82 VanDerWaalsContact CA-O 3.22Å; T53-T82 WeakPolarHBondContact CA-O 3.45Å; T53-T82 HydrophobicContact CG2-CG2 4.41Å; T53-N84 VanDerWaalsContact CG2-ND2 3.27Å; T53-N84 WeakPolarHBondContact CG2-ND2 3.43Å
54I98.7Very high97.1Very high0 Ų025.6 Ų25.60%018%0.184CC..EExtended strand (participates in β ladder)trans-109.9122.5174.3-64167.6000108.1I47 I56 V74 Y78 V81 T82 I83 N84 D137I47-I54 HydrophobicContact CD1-CG2 4.15Å; I54-I56 HydrophobicContact CG2-CD1 4.23Å; I54-I56 HydrophobicContact CG2-CG1 3.92Å; I54-V74 HydrophobicContact CD1-CG1 3.88Å; I54-V74 HydrophobicContact CG2-CG1 4.23Å; I54-Y78 HydrophobicContact CD1-CD1 4.33Å; I54-Y78 HydrophobicContact CD1-CD2 3.39Å; I54-Y78 HydrophobicContact CD1-CE2 4.01Å; I54-Y78 HydrophobicContact CD1-CG 3.57Å; I54-V81 HydrophobicContact CD1-CB 4.5Å; I54-V81 HydrophobicContact CD1-CG1 3.89Å; I54-V81 HydrophobicContact CG1-CG1 3.82Å; I54-T82 PolarHBondContact N-O 2.98Å; I54-I83 CarbonylContact O-C 3.51Å; I54-I83 WeakPolarHBondContact O-CA 3.46Å; I54-N84 PolarHBondContact O-N 3.36Å; I54-D137 VanDerWaalsContact CA-OD2 3.3Å; I54-D137 WeakPolarHBondContact CA-OD2 3.29Å; I54-D137 HydrophobicContact CG2-CB 3.9Å
55N98.7Very high97Very high33 Ų3329.1 Ų29.118%0.17620%0.2CC..EExtended strand (participates in β ladder)trans-98.3121.3177.3-57.9-70.7000109.8N84 W136 D137 F138N55-N84 WeakPolarHBondContact CA-O 3.34Å; N55-N84 WeakPolarHBondContact OD1-CB 3.49Å; N55-N84 PolarHBondContact OD1-ND2 2.81Å; N55-W136 HydrophobicContact CB-CD2 4.49Å; N55-W136 HydrophobicContact CB-CE3 3.69Å; N55-W136 HydrophobicContact CB-CZ3 4.12Å; N55-D137 PolarHBondContact N-OD2 2.61Å; N55-D137 WeakPolarHBondContact O-CB 3.19Å; N55-D137 PolarHBondContact O-N 2.93Å; N55-F138 PolarHBondContact O-N 3.05Å
56I98.9Very high97Very high2 Ų227.3 Ų27.31%0.0119%0.187CC..EExtended strand (participates in β ladder)trans-118.8131.4-179.1-56.4-177.3000109.4I54 L71 V74 I83 N84 N85 E86 W136 F138I54-I56 HydrophobicContact CG2-CD1 4.23Å; I54-I56 HydrophobicContact CG2-CG1 3.92Å; I56-L71 HydrophobicContact CD1-CD2 3.64Å; I56-V74 HydrophobicContact CD1-CB 4.36Å; I56-V74 HydrophobicContact CD1-CG1 4.15Å; I56-V74 HydrophobicContact CD1-CG2 3.88Å; I56-I83 HydrophobicContact CD1-CG2 3.73Å; I56-I83 HydrophobicContact CG1-CG2 4.14Å; I56-N84 PolarHBondContact N-O 3.22Å; I56-N85 WeakPolarHBondContact O-CA 3.43Å; I56-E86 PolarHBondContact O-N 3.06Å; I56-W136 VanDerWaalsContact C-CE3 3.42Å; I56-W136 WeakPolarHBondContact O-CZ3 3.42Å; I56-F138 CarbonylContact C-O 3.57Å; I56-F138 VanDerWaalsContact CA-O 3.27Å; I56-F138 WeakPolarHBondContact CA-O 3.47Å; I56-F138 HydrophobicContact CG1-CB 4.18Å; I56-F138 HydrophobicContact CG2-CB 4.41Å; I56-F138 HydrophobicContact CG2-CD1 3.89Å
57L98.9Very high97.1Very high0 Ų026.3 Ų26.30%018%0.179CC..EExtended strand (participates in β ladder)trans-114115.1174-171.661000110.5V59 E86 I88 Y123 W136 F138 I139 H140 F158L57-V59 HydrophobicContact CD2-CG2 4.47Å; L57-V59 HydrophobicContact CG-CG2 4.24Å; L57-E86 WeakPolarHBondContact CA-O 3.41Å; L57-E86 HydrophobicContact CD1-CB 4.01Å; L57-I88 HydrophobicContact CD1-CD1 3.9Å; L57-I88 HydrophobicContact CD1-CG1 4.06Å; L57-I88 HydrophobicContact CD2-CD1 4.19Å; L57-I88 HydrophobicContact CG-CD1 4.23Å; L57-Y123 HydrophobicContact CD2-CE1 4.28Å; L57-W136 HydrophobicContact CB-CD2 3.63Å; L57-W136 HydrophobicContact CB-CE3 3.64Å; L57-W136 HydrophobicContact CB-CG 4.07Å; L57-W136 HydrophobicContact CB-CH2 4.22Å; L57-W136 HydrophobicContact CB-CZ2 4.27Å; L57-W136 HydrophobicContact CB-CZ3 3.95Å; L57-W136 HydrophobicContact CD1-CH2 3.85Å; L57-W136 HydrophobicContact CD1-CZ2 3.89Å; L57-W136 HydrophobicContact CD1-CZ3 4.34Å; L57-W136 HydrophobicContact CD2-CD2 4.28Å; L57-W136 HydrophobicContact CD2-CG 4.5Å; L57-W136 HydrophobicContact CD2-CZ2 4.15Å; L57-W136 HydrophobicContact CG-CD2 4.45Å; L57-W136 HydrophobicContact CG-CZ2 4.34Å; L57-F138 PolarHBondContact N-O 3.44Å; L57-I139 HydrophobicContact CB-CG1 4.14Å; L57-I139 HydrophobicContact CB-CG2 4.28Å; L57-I139 HydrophobicContact CD2-CG2 4.47Å; L57-I139 VanDerWaalsContact O-CA 3.31Å; L57-I139 WeakPolarHBondContact O-CA 3.25Å; L57-H140 PolarHBondContact O-N 3.47Å; L57-F158 HydrophobicContact CD2-CD1 3.82Å; L57-F158 HydrophobicContact CD2-CE1 3.63Å
58S98.9Very high97.1Very high0 Ų027.3 Ų27.30%018%0.184CC..EExtended strand (participates in β ladder)trans-93.5114172174.60000109.3G61 D67 E86 V87 I88 H140S58-G61 WeakPolarHBondContact OG-CA 3.4Å; S58-D67 WeakPolarHBondContact CB-OD1 3.13Å; S58-D67 PolarHBondContact OG-OD1 3.5Å; S58-D67 PolarHBondContact OG-OD2 3.32Å; S58-E86 PolarHBondContact N-O 3.38Å; S58-V87 CarbonylContact O-C 3.45Å; S58-V87 WeakPolarHBondContact O-CA 3.46Å; S58-I88 PolarHBondContact O-N 2.83Å; S58-H140 VanDerWaalsContact CA-CE1 3.48Å; S58-H140 WeakPolarHBondContact CA-CE1 3.2Å; S58-H140 WeakPolarHBondContact CB-CE1 3.4Å; S58-H140 WeakPolarHBondContact CB-NE2 3.27Å; S58-H140 PolarHBondContact OG-CE1 3.35Å
59V98.8Very high97.2Very high0 Ų029.7 Ų29.70%020%0.196CC..EExtended strand (participates in β ladder)trans-102.8119.3175.4-159.20000107.9L57 I88 A120 I139 H140 M141 M144 F158L57-V59 HydrophobicContact CD2-CG2 4.47Å; L57-V59 HydrophobicContact CG-CG2 4.24Å; V59-I88 HydrophobicContact CG1-CB 4.34Å; V59-I88 HydrophobicContact CG1-CD1 4.21Å; V59-I88 HydrophobicContact CG2-CD1 4.29Å; V59-A120 HydrophobicContact CG1-CB 3.8Å; V59-I139 HydrophobicContact CG2-CG2 4Å; V59-H140 PolarHBondContact N-O 2.83Å; V59-M141 HydrophobicContact CB-CG 4.02Å; V59-M141 HydrophobicContact CG2-CE 4.3Å; V59-M141 HydrophobicContact CG2-CG 4.15Å; V59-M144 HydrophobicContact CB-CE 4.15Å; V59-M144 HydrophobicContact CG1-CE 3.44Å; V59-M144 VanDerWaalsContact CG1-CE 3.44Å; V59-M144 HydrophobicContact CG1-SD 4.34Å; V59-M144 WeakPolarHBondContact O-CG 3.48Å; V59-F158 HydrophobicContact CG1-CE2 4.24Å; V59-F158 HydrophobicContact CG1-CZ 3.91Å; V59-F158 HydrophobicContact CG2-CD1 4.06Å; V59-F158 HydrophobicContact CG2-CE1 3.72Å; V59-F158 HydrophobicContact CG2-CE2 4.46Å; V59-F158 HydrophobicContact CG2-CZ 3.94Å
60G97.7Very high97.4Very high18 Ų1826.3 Ų26.319%0.18618%0.178CC..SBendtrans7142.3-172.200000113G62 I88G60-G62 PolarHBondContact O-N 3.17Å; G60-G62 VanDerWaalsContact O-N 3.1Å; G60-I88 WeakPolarHBondContact CA-O 3.5Å; G60-I88 PolarHBondContact N-O 3.24Å
61G97.1Very high97.7Very high7 Ų721.9 Ų21.97%0.07213%0.132CC..  trans-65.7-10.3-173.600000115.7S58 A63 G64S58-G61 WeakPolarHBondContact OG-CA 3.4Å; G61-A63 PolarHBondContact O-N 2.94Å; G61-G64 PolarHBondContact O-N 3.36Å
62G95.4Very high97.8Very high10 Ų1021.4 Ų21.410%0.10314%0.135CC..THydrogen-bonded Turntrans54.7-132.8175.400000112.8G60 G64 E89 Q94 Y98G60-G62 PolarHBondContact O-N 3.17Å; G60-G62 VanDerWaalsContact O-N 3.1Å; G62-G64 VanDerWaalsContact C-N 3.3Å; G62-E89 WeakPolarHBondContact CA-OE2 3.42Å; G62-E89 PolarHBondContact N-OE2 2.86Å; G62-Q94 CarbonylContact O-C 3.54Å; G62-Y98 WeakPolarHBondContact O-CD1 3.44Å
63A95.9Very high97.9Very high19 Ų1919.1 Ų19.116%0.15711%0.113CC..THydrogen-bonded Turntrans-87.18.8179.100000114.2G61 E65 Y98 R101G61-A63 PolarHBondContact O-N 2.94Å; A63-E65 PolarHBondContact O-N 2.97Å; A63-Y98 WeakPolarHBondContact O-CA 3.26Å; A63-R101 PolarHBondContact O-NE 3.15Å; A63-R101 VanDerWaalsContact O-NE 3.1Å
64G97.4Very high97.9Very high1 Ų117.1 Ų17.11%0.0110%0.101CC..SBendtrans76.111.6170.500000117.1G61 G62 L68 Y98G61-G64 PolarHBondContact O-N 3.36Å; G62-G64 VanDerWaalsContact C-N 3.3Å; G64-L68 WeakPolarHBondContact O-CB 3.36Å; G64-L68 VanDerWaalsContact O-CG 3.29Å; G64-L68 WeakPolarHBondContact O-CG 3.35Å; G64-L68 PolarHBondContact O-N 3.1Å; G64-L68 VanDerWaalsContact O-N 3.1Å; G64-Y98 VanDerWaalsContact CA-CD1 3.4Å
65E95.6Very high97.9Very high74 Ų7418.8 Ų18.835%0.34611%0.109SC..Hα-helixtrans-62.1-54.4179.6-75.2176.215300111.9H29 A63 L69 R101H29-E65 IonicContact CE1-OE2 3.78Å; H29-E65 PolarHBondContact CE1-OE2 2.6Å; H29-E65 IonicContact ND1-OE2 3.84Å; H29-E65 PolarHBondContact ND1-OE2 2.8Å; A63-E65 PolarHBondContact O-N 2.97Å; E65-L69 WeakPolarHBondContact O-CG 3.3Å; E65-L69 PolarHBondContact O-N 3.36Å; E65-R101 VanDerWaalsContact CD-NH2 3.27Å; E65-R101 IonicContact OE1-CZ 2.6Å; E65-R101 VanDerWaalsContact OE1-CZ 3.26Å; E65-R101 IonicContact OE1-NH1 3.34Å; E65-R101 PolarHBondContact OE1-NH1 2.96Å; E65-R101 IonicContact OE1-NH2 3.09Å; E65-R101 PolarHBondContact OE1-NH2 3.05Å
66I97Very high97.8Very high12 Ų1221.1 Ų21.16%0.06213%0.132CC..Hα-helixtrans-70.6-39.9-178.6-59.9-56.3000110.9M32 I36 L68 L69 M70 V142M32-I66 HydrophobicContact CB-CD1 3.95Å; M32-I66 HydrophobicContact SD-CD1 3.8Å; M32-I66 HydrophobicContact SD-CG1 3.87Å; I36-I66 HydrophobicContact CD1-CG2 3.86Å; I66-L68 PolarHBondContact O-N 3.07Å; I66-L69 HydrophobicContact CD1-CD1 4.34Å; I66-L69 WeakPolarHBondContact O-CB 3.06Å; I66-L69 PolarHBondContact O-N 3.15Å; I66-M70 HydrophobicContact CG2-CE 3.91Å; I66-M70 HydrophobicContact CG2-SD 4.47Å; I66-M70 WeakPolarHBondContact O-CG 3.4Å; I66-M70 PolarHBondContact O-N 2.82Å; I66-V142 HydrophobicContact CG2-CG1 4.37Å; I66-V142 HydrophobicContact CG2-CG2 4.22Å
67D98.6Very high97.7Very high5 Ų525.9 Ų25.93%0.02715%0.15CC..Hα-helixtrans-54.5-51.1174.8-69.7-138.4000112.7S58 L69 M70 L71 Y98 H140S58-D67 WeakPolarHBondContact CB-OD1 3.13Å; S58-D67 PolarHBondContact OG-OD1 3.5Å; S58-D67 PolarHBondContact OG-OD2 3.32Å; D67-L69 VanDerWaalsContact C-N 3.27Å; D67-L69 PolarHBondContact O-N 3.28Å; D67-M70 PolarHBondContact O-N 2.78Å; D67-M70 VanDerWaalsContact O-N 3.14Å; D67-L71 WeakPolarHBondContact O-CB 3.47Å; D67-L71 VanDerWaalsContact O-CG 3.25Å; D67-L71 WeakPolarHBondContact O-CG 3.27Å; D67-L71 PolarHBondContact O-N 3.08Å; D67-Y98 HydrophobicContact CB-CE1 4.14Å; D67-Y98 WeakPolarHBondContact CB-OH 3.38Å; D67-Y98 VanDerWaalsContact CG-OH 3.23Å; D67-Y98 WeakPolarHBondContact OD1-CE1 3.48Å; D67-Y98 PolarHBondContact OD1-OH 3.2Å; D67-H140 IonicContact OD1-CE1 2.68Å; D67-H140 IonicContact OD1-NE2 2.61Å; D67-H140 IonicContact OD2-CE1 3.4Å
68L98.4Very high97.7Very high21 Ų2126.6 Ų26.611%0.1115%0.153CC..Hα-helixtrans-64.8-33.4-178.6-70.7179.9000111.9G64 I66 L71 S72 Y98 R101 V102 T105 L108 F113G64-L68 WeakPolarHBondContact O-CB 3.36Å; G64-L68 VanDerWaalsContact O-CG 3.29Å; G64-L68 WeakPolarHBondContact O-CG 3.35Å; G64-L68 PolarHBondContact O-N 3.1Å; G64-L68 VanDerWaalsContact O-N 3.1Å; I66-L68 PolarHBondContact O-N 3.07Å; L68-L71 HydrophobicContact CD2-CD1 4.07Å; L68-S72 WeakPolarHBondContact O-CB 2.95Å; L68-S72 PolarHBondContact O-N 3.32Å; L68-Y98 HydrophobicContact CG-CE2 4.48Å; L68-R101 HydrophobicContact CD1-CB 4.44Å; L68-R101 HydrophobicContact CD1-CG 3.59Å; L68-V102 HydrophobicContact CD2-CG2 4.36Å; L68-T105 HydrophobicContact CD1-CG2 4.48Å; L68-L108 HydrophobicContact CD2-CD1 4.04Å; L68-L108 HydrophobicContact CD2-CD2 4.19Å; L68-F113 HydrophobicContact CD2-CE1 4.27Å; L68-F113 HydrophobicContact CD2-CZ 3.89Å
69L97.9Very high97.5Very high54 Ų5431.8 Ų31.828%0.28319%0.187SC..Hα-helixtrans-63.3-46.8172.1-68.7176.2000111.1Q33 I36 E65 I66 D67 S72 K73Q33-L69 HydrophobicContact CB-CD1 4.29Å; Q33-L69 HydrophobicContact CG-CD1 4.29Å; I36-L69 HydrophobicContact CD1-CB 4.04Å; I36-L69 HydrophobicContact CD1-CD1 4.42Å; I36-L69 HydrophobicContact CG2-CB 4.06Å; E65-L69 WeakPolarHBondContact O-CG 3.3Å; E65-L69 PolarHBondContact O-N 3.36Å; I66-L69 HydrophobicContact CD1-CD1 4.34Å; I66-L69 WeakPolarHBondContact O-CB 3.06Å; I66-L69 PolarHBondContact O-N 3.15Å; D67-L69 VanDerWaalsContact C-N 3.27Å; D67-L69 PolarHBondContact O-N 3.28Å; L69-S72 PolarHBondContact O-N 2.74Å; L69-S72 PolarHBondContact O-OG 3.29Å; L69-K73 PolarHBondContact O-N 2.53Å
70M98.6Very high97.3Very high4 Ų435.5 Ų35.52%0.0223%0.225CC..Hα-helixtrans-63.9-44.8177.1-67.2-171.4-70.500112I36 L40 I66 D67 S72 K73 V74 F138 H140 V142I36-M70 HydrophobicContact CD1-CG 3.9Å; I36-M70 HydrophobicContact CG1-CG 4.05Å; L40-M70 HydrophobicContact CD2-CB 3.92Å; L40-M70 HydrophobicContact CD2-CG 3.67Å; I66-M70 HydrophobicContact CG2-CE 3.91Å; I66-M70 HydrophobicContact CG2-SD 4.47Å; I66-M70 WeakPolarHBondContact O-CG 3.4Å; I66-M70 PolarHBondContact O-N 2.82Å; D67-M70 PolarHBondContact O-N 2.78Å; D67-M70 VanDerWaalsContact O-N 3.14Å; M70-S72 VanDerWaalsContact C-N 3.26Å; M70-S72 PolarHBondContact O-N 2.86Å; M70-K73 WeakPolarHBondContact O-CB 3.46Å; M70-K73 PolarHBondContact O-N 2.76Å; M70-V74 WeakPolarHBondContact O-CG2 3.2Å; M70-V74 PolarHBondContact O-N 2.8Å; M70-F138 HydrophobicContact SD-CE1 3.99Å; M70-F138 HydrophobicContact SD-CZ 4.17Å; M70-H140 HydrophobicContact CE-CB 4.27Å; M70-H140 WeakPolarHBondContact CE-CE1 3.42Å; M70-H140 WeakPolarHBondContact CE-ND1 3.49Å; M70-H140 WeakPolarHBondContact CE-NE2 3.49Å; M70-H140 HydrophobicContact SD-CB 4.48Å; M70-V142 HydrophobicContact CE-CG2 4.44Å
71L98.7Very high97.2Very high2 Ų235.8 Ų35.81%0.0122%0.223CC..Hα-helixtrans-58-39.4177.2-72.7168.1000111.6I56 D67 L68 K73 V74 Q75 I83 N85 I111 F113I56-L71 HydrophobicContact CD1-CD2 3.64Å; D67-L71 WeakPolarHBondContact O-CB 3.47Å; D67-L71 VanDerWaalsContact O-CG 3.25Å; D67-L71 WeakPolarHBondContact O-CG 3.27Å; D67-L71 PolarHBondContact O-N 3.08Å; L68-L71 HydrophobicContact CD2-CD1 4.07Å; L71-K73 VanDerWaalsContact C-N 3.27Å; L71-K73 PolarHBondContact O-N 2.85Å; L71-V74 PolarHBondContact O-N 2.81Å; L71-Q75 WeakPolarHBondContact O-CG 3.48Å; L71-Q75 PolarHBondContact O-N 2.9Å; L71-I83 HydrophobicContact CD2-CG2 3.82Å; L71-N85 HydrophobicContact CD1-CB 4.33Å; L71-N85 HydrophobicContact CD2-CB 4.11Å; L71-I111 HydrophobicContact CB-CD1 3.98Å; L71-I111 HydrophobicContact CD1-CD1 4.32Å; L71-I111 HydrophobicContact CD2-CD1 4.24Å; L71-I111 HydrophobicContact CG-CD1 4.42Å; L71-F113 HydrophobicContact CD1-CE1 3.73Å; L71-F113 HydrophobicContact CD1-CZ 3.86Å
72S98.2Very high97.3Very high45 Ų4537.7 Ų37.732%0.31523%0.233SC..Hα-helixtrans-59.8-37175.4820000112.6L68 L69 M70 A76L68-S72 WeakPolarHBondContact O-CB 2.95Å; L68-S72 PolarHBondContact O-N 3.32Å; L69-S72 PolarHBondContact O-N 2.74Å; L69-S72 PolarHBondContact O-OG 3.29Å; M70-S72 VanDerWaalsContact C-N 3.26Å; M70-S72 PolarHBondContact O-N 2.86Å; S72-A76 WeakPolarHBondContact O-CB 3.49Å; S72-A76 PolarHBondContact O-N 2.97Å
73K98.5Very high97.5Very high53 Ų5337.3 Ų37.323%0.2323%0.229CC..Hα-helixtrans-72.4-37.7176.8-55.1-53.6176.5-177.60111.6I36 L40 I44 L69 M70 L71 A76 R77I36-K73 HydrophobicContact CG2-CD 4.46Å; I36-K73 HydrophobicContact CG2-CG 3.69Å; I36-K73 WeakPolarHBondContact O-CE 3.33Å; I36-K73 WeakPolarHBondContact O-CG 3.21Å; L40-K73 HydrophobicContact CD2-CB 4.18Å; L40-K73 HydrophobicContact CD2-CG 4.21Å; I44-K73 HydrophobicContact CD1-CB 3.88Å; L69-K73 PolarHBondContact O-N 2.53Å; M70-K73 WeakPolarHBondContact O-CB 3.46Å; M70-K73 PolarHBondContact O-N 2.76Å; L71-K73 VanDerWaalsContact C-N 3.27Å; L71-K73 PolarHBondContact O-N 2.85Å; K73-A76 PolarHBondContact O-N 3.33Å; K73-R77 WeakPolarHBondContact O-CB 3.24Å; K73-R77 PolarHBondContact O-N 2.9Å
74V98.4Very high97.6Very high0 Ų038.1 Ų38.10%023%0.231CC..Hα-helixtrans-62.4-48.3173.5-179.50000110.4I44 I47 I54 I56 M70 L71 A76 R77 Y78 I83I44-V74 HydrophobicContact CD1-CB 4.36Å; I44-V74 HydrophobicContact CD1-CG2 3.73Å; I47-V74 HydrophobicContact CD1-CG2 4.37Å; I54-V74 HydrophobicContact CD1-CG1 3.88Å; I54-V74 HydrophobicContact CG2-CG1 4.23Å; I56-V74 HydrophobicContact CD1-CB 4.36Å; I56-V74 HydrophobicContact CD1-CG1 4.15Å; I56-V74 HydrophobicContact CD1-CG2 3.88Å; M70-V74 WeakPolarHBondContact O-CG2 3.2Å; M70-V74 PolarHBondContact O-N 2.8Å; L71-V74 PolarHBondContact O-N 2.81Å; V74-A76 PolarHBondContact O-N 2.67Å; V74-R77 PolarHBondContact O-N 3.15Å; V74-Y78 HydrophobicContact CG1-CD2 4.08Å; V74-Y78 WeakPolarHBondContact O-CD2 3.16Å; V74-Y78 PolarHBondContact O-N 3.27Å; V74-I83 HydrophobicContact CB-CD1 4.14Å; V74-I83 HydrophobicContact CG1-CD1 3.72Å; V74-I83 HydrophobicContact CG1-CG1 4.34Å
75Q97.4Very high97.7Very high35 Ų3538.1 Ų38.116%0.16423%0.23CC..Hα-helixtrans-59.1-45.7176.7-72.5177.5-64.900112.1L71 R77 Y78 I83 N107 N110 I111L71-Q75 WeakPolarHBondContact O-CG 3.48Å; L71-Q75 PolarHBondContact O-N 2.9Å; Q75-R77 VanDerWaalsContact C-N 3.27Å; Q75-R77 PolarHBondContact O-N 3.2Å; Q75-Y78 CarbonylContact O-C 3.48Å; Q75-Y78 VanDerWaalsContact O-C 3.28Å; Q75-Y78 PolarHBondContact O-N 3.23Å; Q75-I83 HydrophobicContact CB-CD1 4.47Å; Q75-I83 HydrophobicContact CG-CD1 3.5Å; Q75-N107 PolarHBondContact NE2-O 2.87Å; Q75-N110 PolarHBondContact NE2-OD1 3.26Å; Q75-I111 HydrophobicContact CG-CD1 4.04Å; Q75-I111 HydrophobicContact CG-CG1 4.42Å
76A97.3Very high97.8Very high81 Ų8136 Ų3667%0.66922%0.22SC*.Hα-helixtrans-62-36.3178.500000112.2S72 K73 V74S72-A76 WeakPolarHBondContact O-CB 3.49Å; S72-A76 PolarHBondContact O-N 2.97Å; K73-A76 PolarHBondContact O-N 3.33Å; V74-A76 PolarHBondContact O-N 2.67Å
77R97.7Very high97.9Very high102 Ų10235.5 Ų35.539%0.38522%0.218SC..Hα-helixtrans-75.1-31.5178.7-178.861.3-171.988.72.9113S45 K73 V74 Q75S45-R77 PolarHBondContact O-NE 3.01Å; S45-R77 PolarHBondContact O-NH2 3.41Å; K73-R77 WeakPolarHBondContact O-CB 3.24Å; K73-R77 PolarHBondContact O-N 2.9Å; V74-R77 PolarHBondContact O-N 3.15Å; Q75-R77 VanDerWaalsContact C-N 3.27Å; Q75-R77 PolarHBondContact O-N 3.2Å
78Y97.3Very high97.9Very high16 Ų1635.3 Ų35.36%0.06322%0.217CC..SBendtrans-129.466.9-173.6-58.8-72.6000111.7I44 S45 S46 I47 G48 I54 V74 Q75 G80 V81I44-Y78 WeakPolarHBondContact O-CE2 3.48Å; I44-Y78 PolarHBondContact O-OH 3.33Å; S45-Y78 PolarHBondContact O-OH 2.65Å; S46-Y78 VanDerWaalsContact C-OH 3.22Å; S46-Y78 WeakPolarHBondContact CA-OH 3.09Å; S46-Y78 PolarHBondContact N-OH 2.98Å; I47-Y78 HydrophobicContact CG1-CE2 3.8Å; I47-Y78 PolarHBondContact N-OH 3.2Å; G48-Y78 VanDerWaalsContact N-CZ 3.32Å; G48-Y78 PolarHBondContact N-OH 2.99Å; G48-Y78 VanDerWaalsContact N-OH 3.09Å; I54-Y78 HydrophobicContact CD1-CD1 4.33Å; I54-Y78 HydrophobicContact CD1-CD2 3.39Å; I54-Y78 HydrophobicContact CD1-CE2 4.01Å; I54-Y78 HydrophobicContact CD1-CG 3.57Å; V74-Y78 HydrophobicContact CG1-CD2 4.08Å; V74-Y78 WeakPolarHBondContact O-CD2 3.16Å; V74-Y78 PolarHBondContact O-N 3.27Å; Q75-Y78 CarbonylContact O-C 3.48Å; Q75-Y78 VanDerWaalsContact O-C 3.28Å; Q75-Y78 PolarHBondContact O-N 3.23Å; Y78-G80 PolarHBondContact O-N 3.39Å; Y78-V81 WeakPolarHBondContact O-CB 3.36Å; Y78-V81 PolarHBondContact O-N 3.35Å
79P95.6Very high97.9Very high109 Ų10935.1 Ų35.171%0.70822%0.215SC*.THydrogen-bonded Turntrans-62133.8-176.526.3-34.9000111.3V81P79-V81 VanDerWaalsContact C-N 3.25Å; P79-V81 PolarHBondContact O-N 3Å
80G93.4Very high97.8Very high78 Ų7835.7 Ų35.780%0.80422%0.222SC*.THydrogen-bonded Turntrans79.7-4.7178.700000115.5Y78Y78-G80 PolarHBondContact O-N 3.39Å
81V97.4Very high97.5Very high24 Ų2436.7 Ų36.715%0.14523%0.23CC..  trans-78.5139.2174.9-179.40000109.8I54 Y78 P79 N110I54-V81 HydrophobicContact CD1-CB 4.5Å; I54-V81 HydrophobicContact CD1-CG1 3.89Å; I54-V81 HydrophobicContact CG1-CG1 3.82Å; Y78-V81 WeakPolarHBondContact O-CB 3.36Å; Y78-V81 PolarHBondContact O-N 3.35Å; P79-V81 VanDerWaalsContact C-N 3.25Å; P79-V81 PolarHBondContact O-N 3Å; V81-N110 PolarHBondContact O-ND2 3.08Å
82T98.3Very high97.3Very high47 Ų4739.1 Ų39.129%0.28825%0.25SC..EExtended strand (participates in β ladder)trans-73.4136.7174.8-61.40000109.7S52 T53 I54S52-T82 PolarHBondContact O-N 3.14Å; T53-T82 CarbonylContact C-O 3.54Å; T53-T82 VanDerWaalsContact CA-O 3.22Å; T53-T82 WeakPolarHBondContact CA-O 3.45Å; T53-T82 HydrophobicContact CG2-CG2 4.41Å; I54-T82 PolarHBondContact N-O 2.98Å
83I98.8Very high97.1Very high1 Ų142 Ų421%0.00526%0.258CS..EExtended strand (participates in β ladder)trans-112.6125.6174.8-57.2174.3000108.5I54 I56 L71 V74 Q75 N110 I111 K112I54-I83 CarbonylContact O-C 3.51Å; I54-I83 WeakPolarHBondContact O-CA 3.46Å; I56-I83 HydrophobicContact CD1-CG2 3.73Å; I56-I83 HydrophobicContact CG1-CG2 4.14Å; L71-I83 HydrophobicContact CD2-CG2 3.82Å; V74-I83 HydrophobicContact CB-CD1 4.14Å; V74-I83 HydrophobicContact CG1-CD1 3.72Å; V74-I83 HydrophobicContact CG1-CG1 4.34Å; Q75-I83 HydrophobicContact CB-CD1 4.47Å; Q75-I83 HydrophobicContact CG-CD1 3.5Å; I83-N110 PolarHBondContact N-O 3.35Å; I83-I111 HydrophobicContact CB-CB 4.45Å; I83-I111 HydrophobicContact CB-CG1 4.16Å; I83-I111 HydrophobicContact CB-CG2 4.17Å; I83-I111 HydrophobicContact CD1-CD1 4.24Å; I83-I111 HydrophobicContact CD1-CG1 4.27Å; I83-I111 HydrophobicContact CG2-CG2 4.16Å; I83-I111 CarbonylContact O-C 3.53Å; I83-I111 WeakPolarHBondContact O-CA 3.33Å; I83-K112 PolarHBondContact O-N 2.83Å
84N98.7Very high96.9Very high37 Ų3742.3 Ų42.320%0.19826%0.26CS..EExtended strand (participates in β ladder)trans-100.5108.6167.4-64.7-29000107.6T53 I54 N55 I56T53-N84 VanDerWaalsContact CG2-ND2 3.27Å; T53-N84 WeakPolarHBondContact CG2-ND2 3.43Å; I54-N84 PolarHBondContact O-N 3.36Å; N55-N84 WeakPolarHBondContact CA-O 3.34Å; N55-N84 WeakPolarHBondContact OD1-CB 3.49Å; N55-N84 PolarHBondContact OD1-ND2 2.81Å; I56-N84 PolarHBondContact N-O 3.22Å
85N98.8Very high96.9Very high0 Ų042.9 Ų42.90%026%0.264CS..EExtended strand (participates in β ladder)trans-104.9110177.8-17477.1000109.9I56 L71 V87 Y98 I111 K112 F113 T114I56-N85 WeakPolarHBondContact O-CA 3.43Å; L71-N85 HydrophobicContact CD1-CB 4.33Å; L71-N85 HydrophobicContact CD2-CB 4.11Å; N85-V87 WeakPolarHBondContact ND2-CG2 3.47Å; N85-Y98 PolarHBondContact ND2-OH 3.09Å; N85-I111 HydrophobicContact CB-CG2 4Å; N85-K112 PolarHBondContact N-O 3.24Å; N85-F113 HydrophobicContact CB-CD1 4.12Å; N85-F113 HydrophobicContact CB-CE1 4.18Å; N85-F113 WeakPolarHBondContact ND2-CD1 3.23Å; N85-F113 VanDerWaalsContact O-CA 3.32Å; N85-F113 WeakPolarHBondContact O-CA 3.12Å; N85-T114 PolarHBondContact O-N 3.1Å
86E98.8Very high96.9Very high30 Ų3047.2 Ų47.214%0.1428%0.282CS..EExtended strand (participates in β ladder)trans-104.1140.8172.9-54.6-160.5-167.700110.7I56 L57 S58 T114 H116 K134 W136I56-E86 PolarHBondContact O-N 3.06Å; L57-E86 WeakPolarHBondContact CA-O 3.41Å; L57-E86 HydrophobicContact CD1-CB 4.01Å; S58-E86 PolarHBondContact N-O 3.38Å; E86-T114 CarbonylContact C-O 3.59Å; E86-T114 WeakPolarHBondContact CA-O 3.43Å; E86-H116 IonicContact OE2-CD2 3.47Å; E86-H116 IonicContact OE2-CE1 2.84Å; E86-H116 IonicContact OE2-NE2 3.14Å; E86-H116 PolarHBondContact OE2-NE2 3.15Å; E86-K134 VanDerWaalsContact CD-NZ 3.35Å; E86-K134 IonicContact OE1-NZ 3.16Å; E86-K134 PolarHBondContact OE1-NZ 2.87Å; E86-W136 HydrophobicContact CB-CH2 3.62Å; E86-W136 HydrophobicContact CB-CZ3 4.05Å; E86-W136 VanDerWaalsContact CD-CH2 3.48Å; E86-W136 HydrophobicContact CG-CH2 3.53Å; E86-W136 HydrophobicContact CG-CZ3 3.94Å
87V98.9Very high96.8Very high1 Ų145.2 Ų45.21%0.00626%0.263CS..EExtended strand (participates in β ladder)trans-123.7126.6-174-173.80000109.4S58 N85 E89 Y98 T114 H116S58-V87 CarbonylContact O-C 3.45Å; S58-V87 WeakPolarHBondContact O-CA 3.46Å; N85-V87 WeakPolarHBondContact ND2-CG2 3.47Å; V87-E89 HydrophobicContact CG1-CB 4.2Å; V87-Y98 HydrophobicContact CB-CE1 4.47Å; V87-Y98 HydrophobicContact CG1-CD1 4.26Å; V87-Y98 HydrophobicContact CG1-CE1 3.97Å; V87-Y98 HydrophobicContact CG2-CD1 4.46Å; V87-Y98 HydrophobicContact CG2-CE1 3.7Å; V87-T114 PolarHBondContact N-O 3.34Å; V87-H116 PolarHBondContact O-N 3.47Å
88I98.7Very high96.9Very high1 Ų140.4 Ų40.41%0.00525%0.245CC..EExtended strand (participates in β ladder)trans-101113170.1-56.6165.9000107L57 S58 V59 G60 E118 Y123 F158L57-I88 HydrophobicContact CD1-CD1 3.9Å; L57-I88 HydrophobicContact CD1-CG1 4.06Å; L57-I88 HydrophobicContact CD2-CD1 4.19Å; L57-I88 HydrophobicContact CG-CD1 4.23Å; S58-I88 PolarHBondContact O-N 2.83Å; V59-I88 HydrophobicContact CG1-CB 4.34Å; V59-I88 HydrophobicContact CG1-CD1 4.21Å; V59-I88 HydrophobicContact CG2-CD1 4.29Å; G60-I88 WeakPolarHBondContact CA-O 3.5Å; G60-I88 PolarHBondContact N-O 3.24Å; I88-E118 HydrophobicContact CG2-CG 4.24Å; I88-E118 VanDerWaalsContact CG2-O 3.24Å; I88-E118 WeakPolarHBondContact CG2-O 3.08Å; I88-Y123 HydrophobicContact CD1-CD1 3.52Å; I88-Y123 HydrophobicContact CD1-CD2 3.41Å; I88-Y123 VanDerWaalsContact CD1-CD2 3.41Å; I88-Y123 HydrophobicContact CD1-CE1 3.84Å; I88-Y123 HydrophobicContact CD1-CE2 3.77Å; I88-Y123 HydrophobicContact CD1-CG 3.29Å; I88-Y123 HydrophobicContact CG1-CD1 4.49Å; I88-Y123 HydrophobicContact CG1-CD2 3.48Å; I88-Y123 VanDerWaalsContact CG1-CD2 3.48Å; I88-Y123 HydrophobicContact CG1-CE2 3.87Å; I88-Y123 HydrophobicContact CG1-CG 3.85Å; I88-F158 HydrophobicContact CD1-CE1 3.92Å; I88-F158 HydrophobicContact CD1-CZ 3.98Å
89E98.2Very high96.9Very high18 Ų1844.2 Ų44.28%0.08426%0.262CS..  trans-148.9115.8-178.717253-117.500110.3G62 V87 S91 Q94 I95 H116 K117 E118G62-E89 WeakPolarHBondContact CA-OE2 3.42Å; G62-E89 PolarHBondContact N-OE2 2.86Å; V87-E89 HydrophobicContact CG1-CB 4.2Å; E89-S91 VanDerWaalsContact C-N 3.33Å; E89-S91 PolarHBondContact O-N 3.18Å; E89-S91 WeakPolarHBondContact OE1-CB 3.48Å; E89-S91 PolarHBondContact OE1-N 3.44Å; E89-Q94 HydrophobicContact CG-CB 3.83Å; E89-I95 HydrophobicContact CB-CD1 4.15Å; E89-I95 HydrophobicContact CB-CG1 3.82Å; E89-I95 HydrophobicContact CG-CD1 4.31Å; E89-I95 HydrophobicContact CG-CG1 3.75Å; E89-I95 WeakPolarHBondContact O-CD1 3.42Å; E89-H116 PolarHBondContact N-O 2.91Å; E89-K117 WeakPolarHBondContact O-CA 3.33Å; E89-E118 CarbonylContact C-O 3.52Å
90P95.6Very high97.1Very high65 Ų6542.7 Ų42.742%0.42225%0.245SC..SBendtrans-70.7-26.3-178.127.3-35.6000113.7A92 K117 T119P90-A92 PolarHBondContact O-N 3.04Å; P90-K117 WeakPolarHBondContact O-CE 3.23Å; P90-T119 HydrophobicContact CB-CG2 3.96Å; P90-T119 HydrophobicContact CG-CG2 4.32Å
91S93.2Very high97.3Very high26 Ų2643 Ų4318%0.18222%0.222CC..  trans-80.9118.2-177.3178.10000112.4E89 E93 Q94 I95E89-S91 VanDerWaalsContact C-N 3.33Å; E89-S91 PolarHBondContact O-N 3.18Å; E89-S91 WeakPolarHBondContact OE1-CB 3.48Å; E89-S91 PolarHBondContact OE1-N 3.44Å; S91-E93 VanDerWaalsContact C-N 3.27Å; S91-E93 PolarHBondContact O-N 3.45Å; S91-E93 PolarHBondContact OG-N 3.32Å; S91-Q94 PolarHBondContact O-N 3.5Å; S91-Q94 PolarHBondContact OG-N 3.34Å; S91-I95 PolarHBondContact O-N 2.9Å
92A94.9Very high97.3Very high52 Ų5243.1 Ų43.143%0.4322%0.223SC..Hα-helixtrans-64-33.1174.800000112.7P90 F96 K117P90-A92 PolarHBondContact O-N 3.04Å; A92-F96 VanDerWaalsContact O-CB 3.32Å; A92-F96 WeakPolarHBondContact O-CB 3.42Å; A92-F96 PolarHBondContact O-N 3.4Å; A92-K117 HydrophobicContact CB-CD 4.21Å
93E92.9Very high97.3Very high105 Ų10545.1 Ų45.149%0.49124%0.244SC..Hα-helixtrans-68-41.3178-177.1176.6177.400111.3H12 S91 F96 S97H12-E93 IonicContact NE2-OE2 2.63Å; S91-E93 VanDerWaalsContact C-N 3.27Å; S91-E93 PolarHBondContact O-N 3.45Å; S91-E93 PolarHBondContact OG-N 3.32Å; E93-F96 PolarHBondContact O-N 2.95Å; E93-S97 WeakPolarHBondContact O-CB 3.3Å; E93-S97 PolarHBondContact O-N 2.92Å; E93-S97 PolarHBondContact O-OG 2.92Å
94Q94.2Very high97.3Very high60 Ų6052.4 Ų52.428%0.2828%0.276SS..Hα-helixtrans-65.7-46.7175.5-67.5-69.975.500111.1G62 E89 S91 F96 S97 Y98G62-Q94 CarbonylContact O-C 3.54Å; E89-Q94 HydrophobicContact CG-CB 3.83Å; S91-Q94 PolarHBondContact O-N 3.5Å; S91-Q94 PolarHBondContact OG-N 3.34Å; Q94-F96 VanDerWaalsContact C-N 3.29Å; Q94-F96 PolarHBondContact O-N 3.09Å; Q94-S97 PolarHBondContact O-N 3.27Å; Q94-Y98 WeakPolarHBondContact O-CB 3.33Å; Q94-Y98 PolarHBondContact O-N 3.12Å
95I98Very high97.2Very high13 Ų1353.5 Ų53.57%0.06728%0.284CS..Hα-helixtrans-58-42.7174.2-71.5166.2000111.3E89 S91 Y98 K99 W115 K117E89-I95 HydrophobicContact CB-CD1 4.15Å; E89-I95 HydrophobicContact CB-CG1 3.82Å; E89-I95 HydrophobicContact CG-CD1 4.31Å; E89-I95 HydrophobicContact CG-CG1 3.75Å; E89-I95 WeakPolarHBondContact O-CD1 3.42Å; S91-I95 PolarHBondContact O-N 2.9Å; I95-Y98 PolarHBondContact O-N 3.43Å; I95-K99 HydrophobicContact CG2-CD 4.03Å; I95-K99 HydrophobicContact CG2-CG 4.43Å; I95-K99 WeakPolarHBondContact O-CB 3.38Å; I95-K99 WeakPolarHBondContact O-CG 3.48Å; I95-K99 PolarHBondContact O-N 2.92Å; I95-W115 HydrophobicContact CG2-CB 4.06Å; I95-W115 HydrophobicContact CG2-CG 4.07Å; I95-K117 HydrophobicContact CD1-CB 3.72Å; I95-K117 HydrophobicContact CD1-CG 3.94Å
96F97.6Very high97Very high126 Ų12657.6 Ų57.655%0.55331%0.313SS*.Hα-helixtrans-60.8-48.5177.7177.8-95.3000111A92 E93 Q94 Y98 K99 E100A92-F96 VanDerWaalsContact O-CB 3.32Å; A92-F96 WeakPolarHBondContact O-CB 3.42Å; A92-F96 PolarHBondContact O-N 3.4Å; E93-F96 PolarHBondContact O-N 2.95Å; Q94-F96 VanDerWaalsContact C-N 3.29Å; Q94-F96 PolarHBondContact O-N 3.09Å; F96-Y98 VanDerWaalsContact C-N 3.33Å; F96-Y98 PolarHBondContact O-N 3.24Å; F96-K99 PolarHBondContact O-N 3.06Å; F96-E100 HydrophobicContact CD1-CG 4.38Å; F96-E100 HydrophobicContact CE1-CG 3.9Å; F96-E100 WeakPolarHBondContact CE1-OE2 3.46Å; F96-E100 HydrophobicContact CZ-CG 4.02Å; F96-E100 PolarHBondContact O-N 2.97Å
97S96.7Very high96.8Very high39 Ų3961.5 Ų61.527%0.27333%0.334SS..Hα-helixtrans-61.4-39.5177.5-59.70000112.4E93 Q94 E100 R101E93-S97 WeakPolarHBondContact O-CB 3.3Å; E93-S97 PolarHBondContact O-N 2.92Å; E93-S97 PolarHBondContact O-OG 2.92Å; Q94-S97 PolarHBondContact O-N 3.27Å; S97-E100 PolarHBondContact O-N 2.95Å; S97-R101 WeakPolarHBondContact O-CB 3.49Å; S97-R101 PolarHBondContact O-N 2.96Å
98Y98.4Very high96.7Very high0 Ų062.6 Ų62.60%034%0.34CS..Hα-helixtrans-62.4-50.5174.1-161.8153.5000110.3G62 A63 G64 D67 L68 N85 V87 Q94 I95 F96 E100 R101 V102 F113 W115G62-Y98 WeakPolarHBondContact O-CD1 3.44Å; A63-Y98 WeakPolarHBondContact O-CA 3.26Å; G64-Y98 VanDerWaalsContact CA-CD1 3.4Å; D67-Y98 HydrophobicContact CB-CE1 4.14Å; D67-Y98 WeakPolarHBondContact CB-OH 3.38Å; D67-Y98 VanDerWaalsContact CG-OH 3.23Å; D67-Y98 WeakPolarHBondContact OD1-CE1 3.48Å; D67-Y98 PolarHBondContact OD1-OH 3.2Å; L68-Y98 HydrophobicContact CG-CE2 4.48Å; N85-Y98 PolarHBondContact ND2-OH 3.09Å; V87-Y98 HydrophobicContact CB-CE1 4.47Å; V87-Y98 HydrophobicContact CG1-CD1 4.26Å; V87-Y98 HydrophobicContact CG1-CE1 3.97Å; V87-Y98 HydrophobicContact CG2-CD1 4.46Å; V87-Y98 HydrophobicContact CG2-CE1 3.7Å; Q94-Y98 WeakPolarHBondContact O-CB 3.33Å; Q94-Y98 PolarHBondContact O-N 3.12Å; I95-Y98 PolarHBondContact O-N 3.43Å; F96-Y98 VanDerWaalsContact C-N 3.33Å; F96-Y98 PolarHBondContact O-N 3.24Å; Y98-E100 VanDerWaalsContact C-N 3.31Å; Y98-E100 PolarHBondContact O-N 2.82Å; Y98-R101 WeakPolarHBondContact O-CA 3.42Å; Y98-R101 WeakPolarHBondContact O-CB 3.4Å; Y98-R101 PolarHBondContact O-N 3.38Å; Y98-V102 HydrophobicContact CD2-CG2 3.74Å; Y98-V102 HydrophobicContact CE2-CG2 3.73Å; Y98-V102 PolarHBondContact O-N 2.99Å; Y98-F113 HydrophobicContact CE2-CD1 4.38Å; Y98-F113 HydrophobicContact CE2-CE1 4.06Å; Y98-W115 AromaticContact CG-NE1 3.92Å
99K98.6Very high96.5Very high96 Ų9670.1 Ų70.142%0.41738%0.375SS..Hα-helixtrans-57.3-43.2177.4-75.7174.9177.1-179.60112.5I95 F96 R101 V102 A103 W115I95-K99 HydrophobicContact CG2-CD 4.03Å; I95-K99 HydrophobicContact CG2-CG 4.43Å; I95-K99 WeakPolarHBondContact O-CB 3.38Å; I95-K99 WeakPolarHBondContact O-CG 3.48Å; I95-K99 PolarHBondContact O-N 2.92Å; F96-K99 PolarHBondContact O-N 3.06Å; K99-R101 VanDerWaalsContact C-N 3.3Å; K99-R101 PolarHBondContact O-N 2.66Å; K99-V102 PolarHBondContact O-N 2.75Å; K99-A103 WeakPolarHBondContact O-CB 3.2Å; K99-A103 PolarHBondContact O-N 3.11Å; K99-W115 HydrophobicContact CB-CZ2 4.49Å; K99-W115 HydrophobicContact CD-CD2 4.39Å; K99-W115 HydrophobicContact CD-CE3 4.34Å; K99-W115 HydrophobicContact CD-CZ3 4.42Å; K99-W115 VanDerWaalsContact CE-CD2 3.42Å; K99-W115 HydrophobicContact CG-CD2 4Å; K99-W115 HydrophobicContact CG-CE3 4.2Å; K99-W115 HydrophobicContact CG-CH2 3.76Å; K99-W115 HydrophobicContact CG-CZ2 3.54Å; K99-W115 HydrophobicContact CG-CZ3 4.08Å
100E98.4Very high96.4Very high77 Ų7771.3 Ų71.336%0.3638%0.382SS..Hα-helixtrans-60.3-40.5174.3-80.6-154.585.100112.5F96 S97 Y98 A103 K104F96-E100 HydrophobicContact CD1-CG 4.38Å; F96-E100 HydrophobicContact CE1-CG 3.9Å; F96-E100 WeakPolarHBondContact CE1-OE2 3.46Å; F96-E100 HydrophobicContact CZ-CG 4.02Å; F96-E100 PolarHBondContact O-N 2.97Å; S97-E100 PolarHBondContact O-N 2.95Å; Y98-E100 VanDerWaalsContact C-N 3.31Å; Y98-E100 PolarHBondContact O-N 2.82Å; E100-A103 PolarHBondContact O-N 2.79Å; E100-K104 WeakPolarHBondContact O-CD 3.44Å; E100-K104 VanDerWaalsContact O-CG 3.31Å; E100-K104 WeakPolarHBondContact O-CG 3.31Å; E100-K104 PolarHBondContact O-N 3.4Å; E100-K104 IonicContact OE1-NZ 3Å; E100-K104 PolarHBondContact OE1-NZ 3.32Å
101R98.1Very high96.5Very high86 Ų8668.8 Ų68.833%0.32537%0.365SS..Hα-helixtrans-64.6-49.3177.5-170.3179-62.4-86.1-5111.2A63 E65 L68 S97 Y98 K99 A103 K104 T105A63-R101 PolarHBondContact O-NE 3.15Å; A63-R101 VanDerWaalsContact O-NE 3.1Å; E65-R101 VanDerWaalsContact CD-NH2 3.27Å; E65-R101 IonicContact OE1-CZ 2.6Å; E65-R101 VanDerWaalsContact OE1-CZ 3.26Å; E65-R101 IonicContact OE1-NH1 3.34Å; E65-R101 PolarHBondContact OE1-NH1 2.96Å; E65-R101 IonicContact OE1-NH2 3.09Å; E65-R101 PolarHBondContact OE1-NH2 3.05Å; L68-R101 HydrophobicContact CD1-CB 4.44Å; L68-R101 HydrophobicContact CD1-CG 3.59Å; S97-R101 WeakPolarHBondContact O-CB 3.49Å; S97-R101 PolarHBondContact O-N 2.96Å; Y98-R101 WeakPolarHBondContact O-CA 3.42Å; Y98-R101 WeakPolarHBondContact O-CB 3.4Å; Y98-R101 PolarHBondContact O-N 3.38Å; K99-R101 VanDerWaalsContact C-N 3.3Å; K99-R101 PolarHBondContact O-N 2.66Å; R101-A103 VanDerWaalsContact C-N 3.26Å; R101-A103 PolarHBondContact O-N 3.42Å; R101-K104 CarbonylContact O-C 3.58Å; R101-K104 PolarHBondContact O-N 3.03Å; R101-T105 PolarHBondContact O-N 3.25Å; R101-T105 PolarHBondContact O-OG1 3.49Å
102V98.4Very high96.7Very high25 Ų2573.9 Ų73.915%0.15238%0.384CS..Hα-helixtrans-54.6-44.4175172.70000110.7L68 Y98 K99 K104 T105 L108 F113 W115L68-V102 HydrophobicContact CD2-CG2 4.36Å; Y98-V102 HydrophobicContact CD2-CG2 3.74Å; Y98-V102 HydrophobicContact CE2-CG2 3.73Å; Y98-V102 PolarHBondContact O-N 2.99Å; K99-V102 PolarHBondContact O-N 2.75Å; V102-K104 PolarHBondContact O-N 3.41Å; V102-T105 PolarHBondContact O-N 3.15Å; V102-L108 HydrophobicContact CB-CD1 4.44Å; V102-L108 HydrophobicContact CG1-CD1 3.93Å; V102-F113 HydrophobicContact CG1-CD2 3.96Å; V102-F113 HydrophobicContact CG1-CE2 3.86Å; V102-F113 HydrophobicContact CG1-CZ 4.41Å; V102-F113 HydrophobicContact CG2-CD1 4.24Å; V102-F113 HydrophobicContact CG2-CD2 4.47Å; V102-F113 HydrophobicContact CG2-CE1 3.98Å; V102-F113 HydrophobicContact CG2-CE2 4.22Å; V102-F113 HydrophobicContact CG2-CG 4.48Å; V102-F113 HydrophobicContact CG2-CZ 3.97Å; V102-W115 HydrophobicContact CG2-CZ2 4.32Å
103A97.8Very high96.9Very high89 Ų8973 Ų7374%0.73637%0.371SS*.Hα-helixtrans-64-24.7179.400000113.9K99 E100 R101K99-A103 WeakPolarHBondContact O-CB 3.2Å; K99-A103 PolarHBondContact O-N 3.11Å; E100-A103 PolarHBondContact O-N 2.79Å; R101-A103 VanDerWaalsContact C-N 3.26Å; R101-A103 PolarHBondContact O-N 3.42Å
104K97.6Very high97.2Very high155 Ų15570.9 Ų70.967%0.67436%0.364SS*.Hα-helixtrans-95.6-9.7179.5-67.4166.3-169161.50112.8E100 R101 V102E100-K104 WeakPolarHBondContact O-CD 3.44Å; E100-K104 VanDerWaalsContact O-CG 3.31Å; E100-K104 WeakPolarHBondContact O-CG 3.31Å; E100-K104 PolarHBondContact O-N 3.4Å; E100-K104 IonicContact OE1-NZ 3Å; E100-K104 PolarHBondContact OE1-NZ 3.32Å; R101-K104 CarbonylContact O-C 3.58Å; R101-K104 PolarHBondContact O-N 3.03Å; V102-K104 PolarHBondContact O-N 3.41Å
105T97.3Very high97.4Very high59 Ų5971.2 Ų71.236%0.36236%0.363SS..  trans-97.4124.2-177-61.50000111L68 R101 V102 L108L68-T105 HydrophobicContact CD1-CG2 4.48Å; R101-T105 PolarHBondContact O-N 3.25Å; R101-T105 PolarHBondContact O-OG1 3.49Å; V102-T105 PolarHBondContact O-N 3.15Å; T105-L108 HydrophobicContact CG2-CD1 3.74Å; T105-L108 HydrophobicContact CG2-CD2 4.19Å; T105-L108 HydrophobicContact CG2-CG 3.93Å
106S95.8Very high97.4Very high87 Ų8772.2 Ų72.261%0.60837%0.368SS*.SBendtrans-77.5167.4172.555.10000112.3
107N94.4Very high97.5Very high111 Ų11173.1 Ų73.159%0.59437%0.371SS*.SBendtrans66.535.6176.2-51.4-34.4000114.1Q75 E109Q75-N107 PolarHBondContact NE2-O 2.87Å; N107-E109 VanDerWaalsContact C-OE2 3.29Å; N107-E109 VanDerWaalsContact CA-OE2 3.23Å; N107-E109 WeakPolarHBondContact CA-OE2 3.43Å
108L96.6Very high97.5Very high24 Ų2472.4 Ų72.413%0.12636%0.364CS..  trans-112.913.4177.8-58.7-178.1000112.8L68 V102 T105 N110 I111 F113L68-L108 HydrophobicContact CD2-CD1 4.04Å; L68-L108 HydrophobicContact CD2-CD2 4.19Å; V102-L108 HydrophobicContact CB-CD1 4.44Å; V102-L108 HydrophobicContact CG1-CD1 3.93Å; T105-L108 HydrophobicContact CG2-CD1 3.74Å; T105-L108 HydrophobicContact CG2-CD2 4.19Å; T105-L108 HydrophobicContact CG2-CG 3.93Å; L108-N110 VanDerWaalsContact C-N 3.26Å; L108-N110 PolarHBondContact O-N 3.03Å; L108-I111 HydrophobicContact CD2-CD1 3.86Å; L108-I111 PolarHBondContact O-N 3.49Å; L108-F113 HydrophobicContact CD1-CE2 4.26Å; L108-F113 HydrophobicContact CD1-CZ 4.36Å
109E94.1Very high97.4Very high160 Ų16074.9 Ų74.975%0.74838%0.379SS*.THydrogen-bonded Turntrans-64.5-29-170.3-58.379.1-172.700113.2N107 I111N107-E109 VanDerWaalsContact C-OE2 3.29Å; N107-E109 VanDerWaalsContact CA-OE2 3.23Å; N107-E109 WeakPolarHBondContact CA-OE2 3.43Å; E109-I111 VanDerWaalsContact C-N 3.35Å
110N95.1Very high97.3Very high43 Ų4370.7 Ų70.723%0.2336%0.362CS..THydrogen-bonded Turntrans-89.94.1176.469.2-45.5000113.5Q75 V81 I83 L108Q75-N110 PolarHBondContact NE2-OD1 3.26Å; V81-N110 PolarHBondContact O-ND2 3.08Å; I83-N110 PolarHBondContact N-O 3.35Å; L108-N110 VanDerWaalsContact C-N 3.26Å; L108-N110 PolarHBondContact O-N 3.03Å
111I98.4Very high97.2Very high12 Ų1275.1 Ų75.16%0.06238%0.377CS..EExtended strand (participates in β ladder)trans-108.1125.1179.7-45-167.7000110.5L71 Q75 I83 N85 L108 E109 F113L71-I111 HydrophobicContact CB-CD1 3.98Å; L71-I111 HydrophobicContact CD1-CD1 4.32Å; L71-I111 HydrophobicContact CD2-CD1 4.24Å; L71-I111 HydrophobicContact CG-CD1 4.42Å; Q75-I111 HydrophobicContact CG-CD1 4.04Å; Q75-I111 HydrophobicContact CG-CG1 4.42Å; I83-I111 HydrophobicContact CB-CB 4.45Å; I83-I111 HydrophobicContact CB-CG1 4.16Å; I83-I111 HydrophobicContact CB-CG2 4.17Å; I83-I111 HydrophobicContact CD1-CD1 4.24Å; I83-I111 HydrophobicContact CD1-CG1 4.27Å; I83-I111 HydrophobicContact CG2-CG2 4.16Å; I83-I111 CarbonylContact O-C 3.53Å; I83-I111 WeakPolarHBondContact O-CA 3.33Å; N85-I111 HydrophobicContact CB-CG2 4Å; L108-I111 HydrophobicContact CD2-CD1 3.86Å; L108-I111 PolarHBondContact O-N 3.49Å; E109-I111 VanDerWaalsContact C-N 3.35Å; I111-F113 HydrophobicContact CB-CD2 4.43Å; I111-F113 HydrophobicContact CB-CE2 3.77Å; I111-F113 HydrophobicContact CB-CZ 4.23Å; I111-F113 HydrophobicContact CG2-CD2 3.98Å; I111-F113 HydrophobicContact CG2-CE1 4.23Å; I111-F113 HydrophobicContact CG2-CE2 3.47Å; I111-F113 VanDerWaalsContact CG2-CE2 3.47Å; I111-F113 HydrophobicContact CG2-CZ 3.61Å
112K98.5Very high97.2Very high133 Ų13375.7 Ų75.758%0.57838%0.383SS*.EExtended strand (participates in β ladder)trans-100.1123.8171.4-64.3-179.3-176.3173.50109.2I83 N85I83-K112 PolarHBondContact O-N 2.83Å; N85-K112 PolarHBondContact N-O 3.24Å
113F98.8Very high97.1Very high34 Ų3474.5 Ų74.515%0.14938%0.376CS..EExtended strand (participates in β ladder)trans-102.3133.3178.7-68.4-93000111.6L68 L71 N85 Y98 V102 L108 I111 W115L68-F113 HydrophobicContact CD2-CE1 4.27Å; L68-F113 HydrophobicContact CD2-CZ 3.89Å; L71-F113 HydrophobicContact CD1-CE1 3.73Å; L71-F113 HydrophobicContact CD1-CZ 3.86Å; N85-F113 HydrophobicContact CB-CD1 4.12Å; N85-F113 HydrophobicContact CB-CE1 4.18Å; N85-F113 WeakPolarHBondContact ND2-CD1 3.23Å; N85-F113 VanDerWaalsContact O-CA 3.32Å; N85-F113 WeakPolarHBondContact O-CA 3.12Å; Y98-F113 HydrophobicContact CE2-CD1 4.38Å; Y98-F113 HydrophobicContact CE2-CE1 4.06Å; V102-F113 HydrophobicContact CG1-CD2 3.96Å; V102-F113 HydrophobicContact CG1-CE2 3.86Å; V102-F113 HydrophobicContact CG1-CZ 4.41Å; V102-F113 HydrophobicContact CG2-CD1 4.24Å; V102-F113 HydrophobicContact CG2-CD2 4.47Å; V102-F113 HydrophobicContact CG2-CE1 3.98Å; V102-F113 HydrophobicContact CG2-CE2 4.22Å; V102-F113 HydrophobicContact CG2-CG 4.48Å; V102-F113 HydrophobicContact CG2-CZ 3.97Å; L108-F113 HydrophobicContact CD1-CE2 4.26Å; L108-F113 HydrophobicContact CD1-CZ 4.36Å; I111-F113 HydrophobicContact CB-CD2 4.43Å; I111-F113 HydrophobicContact CB-CE2 3.77Å; I111-F113 HydrophobicContact CB-CZ 4.23Å; I111-F113 HydrophobicContact CG2-CD2 3.98Å; I111-F113 HydrophobicContact CG2-CE1 4.23Å; I111-F113 HydrophobicContact CG2-CE2 3.47Å; I111-F113 VanDerWaalsContact CG2-CE2 3.47Å; I111-F113 HydrophobicContact CG2-CZ 3.61Å; F113-W115 HydrophobicContact CB-CE3 4.43Å; F113-W115 HydrophobicContact CB-CH2 3.45Å; F113-W115 VanDerWaalsContact CB-CH2 3.45Å; F113-W115 HydrophobicContact CB-CZ2 3.56Å; F113-W115 HydrophobicContact CB-CZ3 3.91Å; F113-W115 HydrophobicContact CD1-CZ2 4.27Å; F113-W115 HydrophobicContact CG-CH2 4.25Å; F113-W115 HydrophobicContact CG-CZ2 4.07Å
114T98.7Very high97Very high59 Ų5971.9 Ų71.936%0.36235%0.348SS..EExtended strand (participates in β ladder)trans-125.6134.7168.5-52.10000108.5N85 E86 V87N85-T114 PolarHBondContact O-N 3.1Å; E86-T114 CarbonylContact C-O 3.59Å; E86-T114 WeakPolarHBondContact CA-O 3.43Å; V87-T114 PolarHBondContact N-O 3.34Å
115W98.7Very high96.9Very high68 Ų6867.6 Ų67.626%0.25834%0.338SS..EExtended strand (participates in β ladder)trans-119127.1178.6-60.5-89.3000110.3I95 Y98 K99 V102 F113I95-W115 HydrophobicContact CG2-CB 4.06Å; I95-W115 HydrophobicContact CG2-CG 4.07Å; Y98-W115 AromaticContact CG-NE1 3.92Å; K99-W115 HydrophobicContact CB-CZ2 4.49Å; K99-W115 HydrophobicContact CD-CD2 4.39Å; K99-W115 HydrophobicContact CD-CE3 4.34Å; K99-W115 HydrophobicContact CD-CZ3 4.42Å; K99-W115 VanDerWaalsContact CE-CD2 3.42Å; K99-W115 HydrophobicContact CG-CD2 4Å; K99-W115 HydrophobicContact CG-CE3 4.2Å; K99-W115 HydrophobicContact CG-CH2 3.76Å; K99-W115 HydrophobicContact CG-CZ2 3.54Å; K99-W115 HydrophobicContact CG-CZ3 4.08Å; V102-W115 HydrophobicContact CG2-CZ2 4.32Å; F113-W115 HydrophobicContact CB-CE3 4.43Å; F113-W115 HydrophobicContact CB-CH2 3.45Å; F113-W115 VanDerWaalsContact CB-CH2 3.45Å; F113-W115 HydrophobicContact CB-CZ2 3.56Å; F113-W115 HydrophobicContact CB-CZ3 3.91Å; F113-W115 HydrophobicContact CD1-CZ2 4.27Å; F113-W115 HydrophobicContact CG-CH2 4.25Å; F113-W115 HydrophobicContact CG-CZ2 4.07Å
116H98.3Very high96.9Very high34 Ų3468 Ų6816%0.15733%0.333CS..EExtended strand (participates in β ladder)trans-109.3111176.5-54.6-67.9000108.4E86 V87 E89 E118 Y123E86-H116 IonicContact OE2-CD2 3.47Å; E86-H116 IonicContact OE2-CE1 2.84Å; E86-H116 IonicContact OE2-NE2 3.14Å; E86-H116 PolarHBondContact OE2-NE2 3.15Å; V87-H116 PolarHBondContact O-N 3.47Å; E89-H116 PolarHBondContact N-O 2.91Å; H116-E118 VanDerWaalsContact C-N 3.26Å; H116-E118 HydrophobicContact CB-CG 3.99Å; H116-E118 WeakPolarHBondContact CB-OE1 3.23Å; H116-E118 IonicContact CG-OE1 2.67Å; H116-E118 PolarHBondContact O-N 3.44Å; H116-Y123 AromaticContact CD2-CE2 3.93Å
117K98.3Very high96.8Very high145 Ų14564.3 Ų64.363%0.6331%0.306SS*.  trans-81.876.1177.2-170.8-164.8169.3-1740110.1E89 P90 A92 I95E89-K117 WeakPolarHBondContact O-CA 3.33Å; P90-K117 WeakPolarHBondContact O-CE 3.23Å; A92-K117 HydrophobicContact CB-CD 4.21Å; I95-K117 HydrophobicContact CD1-CB 3.72Å; I95-K117 HydrophobicContact CD1-CG 3.94Å
118E97.7Very high96.8Very high24 Ų2463.1 Ų63.111%0.11230%0.3CS..SBendtrans-156.8163.5-178.164.8-168.9162.100110.2I88 E89 H116 E122 Y123 R126I88-E118 HydrophobicContact CG2-CG 4.24Å; I88-E118 VanDerWaalsContact CG2-O 3.24Å; I88-E118 WeakPolarHBondContact CG2-O 3.08Å; E89-E118 CarbonylContact C-O 3.52Å; H116-E118 VanDerWaalsContact C-N 3.26Å; H116-E118 HydrophobicContact CB-CG 3.99Å; H116-E118 WeakPolarHBondContact CB-OE1 3.23Å; H116-E118 IonicContact CG-OE1 2.67Å; H116-E118 PolarHBondContact O-N 3.44Å; E118-E122 HydrophobicContact CB-CB 3.86Å; E118-E122 HydrophobicContact CG-CB 4.5Å; E118-Y123 WeakPolarHBondContact OE1-CD2 3.27Å; E118-R126 IonicContact OE1-CZ 2.72Å; E118-R126 IonicContact OE1-NE 3.87Å; E118-R126 PolarHBondContact OE1-NE 2.86Å; E118-R126 VanDerWaalsContact OE1-NE 3.09Å; E118-R126 IonicContact OE1-NH2 3.06Å; E118-R126 PolarHBondContact OE1-NH2 3.35Å; E118-R126 IonicContact OE2-NE 3.62Å; E118-R126 PolarHBondContact OE2-NE 2.67Å; E118-R126 VanDerWaalsContact OE2-NE 3.16Å
119T96.8Very high96.7Very high51 Ų5165.9 Ų65.931%0.31333%0.326SS..  trans-78.1165.6171.660.70000111.2P90 Y121 E122 Y123P90-T119 HydrophobicContact CB-CG2 3.96Å; P90-T119 HydrophobicContact CG-CG2 4.32Å; T119-Y121 PolarHBondContact O-N 3.18Å; T119-E122 WeakPolarHBondContact CG2-OE2 3.03Å; T119-E122 PolarHBondContact N-OE2 3.37Å; T119-E122 PolarHBondContact O-N 3.07Å; T119-E122 WeakPolarHBondContact OG1-CB 3.27Å; T119-E122 VanDerWaalsContact OG1-CG 3.28Å; T119-E122 WeakPolarHBondContact OG1-CG 3.22Å; T119-E122 PolarHBondContact OG1-N 2.86Å; T119-E122 PolarHBondContact OG1-OE2 3.28Å; T119-Y123 WeakPolarHBondContact O-CB 3.32Å; T119-Y123 PolarHBondContact O-N 2.95Å
120A96.7Very high96.7Very high8 Ų863.5 Ų63.57%0.06632%0.315CS..Hα-helixtrans-58.5-35.3175.400000112.5V59 E124 M144 T154 F158V59-A120 HydrophobicContact CG1-CB 3.8Å; A120-E124 WeakPolarHBondContact O-CB 3.29Å; A120-E124 PolarHBondContact O-N 3.28Å; A120-M144 HydrophobicContact CB-CE 4.32Å; A120-T154 HydrophobicContact CB-CG2 4.44Å; A120-F158 HydrophobicContact CB-CE2 3.93Å; A120-F158 HydrophobicContact CB-CZ 4.1Å
121Y95.3Very high96.4Very high170 Ų17070.1 Ų70.167%0.66734%0.341SS*.Hα-helixtrans-68.9-45.4176.6175.6-99.2000112.6T119 Y123 E124 S125T119-Y121 PolarHBondContact O-N 3.18Å; Y121-Y123 VanDerWaalsContact C-N 3.33Å; Y121-E124 PolarHBondContact O-N 2.99Å; Y121-S125 WeakPolarHBondContact O-CB 3.45Å; Y121-S125 PolarHBondContact O-N 2.93Å
122E97.1Very high95.8Very high99 Ų9973 Ų7346%0.46336%0.357SS..Hα-helixtrans-63.2-42.2176.6-73.7164.414900111E118 T119 S125 R126E118-E122 HydrophobicContact CB-CB 3.86Å; E118-E122 HydrophobicContact CG-CB 4.5Å; T119-E122 WeakPolarHBondContact CG2-OE2 3.03Å; T119-E122 PolarHBondContact N-OE2 3.37Å; T119-E122 PolarHBondContact O-N 3.07Å; T119-E122 WeakPolarHBondContact OG1-CB 3.27Å; T119-E122 VanDerWaalsContact OG1-CG 3.28Å; T119-E122 WeakPolarHBondContact OG1-CG 3.22Å; T119-E122 PolarHBondContact OG1-N 2.86Å; T119-E122 PolarHBondContact OG1-OE2 3.28Å; E122-S125 PolarHBondContact O-N 3.49Å; E122-R126 WeakPolarHBondContact O-CB 3.23Å; E122-R126 PolarHBondContact O-N 3.4Å
123Y97.3Very high95.1Very high0 Ų071.4 Ų71.40%036%0.362CS..Hα-helixtrans-57.8-51.7172.6-177.4-86.9000111.4L57 I88 H116 E118 T119 Y121 S125 R126 M127 W136 Y157 F158L57-Y123 HydrophobicContact CD2-CE1 4.28Å; I88-Y123 HydrophobicContact CD1-CD1 3.52Å; I88-Y123 HydrophobicContact CD1-CD2 3.41Å; I88-Y123 VanDerWaalsContact CD1-CD2 3.41Å; I88-Y123 HydrophobicContact CD1-CE1 3.84Å; I88-Y123 HydrophobicContact CD1-CE2 3.77Å; I88-Y123 HydrophobicContact CD1-CG 3.29Å; I88-Y123 HydrophobicContact CG1-CD1 4.49Å; I88-Y123 HydrophobicContact CG1-CD2 3.48Å; I88-Y123 VanDerWaalsContact CG1-CD2 3.48Å; I88-Y123 HydrophobicContact CG1-CE2 3.87Å; I88-Y123 HydrophobicContact CG1-CG 3.85Å; H116-Y123 AromaticContact CD2-CE2 3.93Å; E118-Y123 WeakPolarHBondContact OE1-CD2 3.27Å; T119-Y123 WeakPolarHBondContact O-CB 3.32Å; T119-Y123 PolarHBondContact O-N 2.95Å; Y121-Y123 VanDerWaalsContact C-N 3.33Å; Y123-S125 VanDerWaalsContact C-N 3.32Å; Y123-S125 PolarHBondContact O-N 3.4Å; Y123-R126 PolarHBondContact O-N 3.15Å; Y123-M127 HydrophobicContact CD1-CG 3.8Å; Y123-M127 HydrophobicContact CD2-CG 4.34Å; Y123-M127 HydrophobicContact CE1-CG 3.5Å; Y123-M127 HydrophobicContact CE1-SD 4.44Å; Y123-M127 HydrophobicContact CE2-CG 4.08Å; Y123-M127 HydrophobicContact CE2-SD 4.2Å; Y123-M127 HydrophobicContact CG-CG 4.21Å; Y123-M127 WeakPolarHBondContact O-CB 3.45Å; Y123-M127 WeakPolarHBondContact O-CG 3.28Å; Y123-M127 PolarHBondContact O-N 2.63Å; Y123-W136 WeakPolarHBondContact OH-CZ2 3.27Å; Y123-Y157 HydrophobicContact CD1-CE1 4.2Å; Y123-Y157 HydrophobicContact CE1-CE1 4.36Å; Y123-F158 HydrophobicContact CD1-CE1 4.25Å; Y123-F158 HydrophobicContact CD1-CZ 4.36Å; Y123-F158 HydrophobicContact CE1-CE1 4.32Å
124E95.8Very high94.9Very high34 Ų3472.1 Ų72.116%0.15937%0.365CS..Hα-helixtrans-55.1-48.6176.5165.7166.8-15900111.4A120 Y121 R126 N128 Y157 R160A120-E124 WeakPolarHBondContact O-CB 3.29Å; A120-E124 PolarHBondContact O-N 3.28Å; Y121-E124 PolarHBondContact O-N 2.99Å; E124-R126 PolarHBondContact O-N 2.72Å; E124-N128 WeakPolarHBondContact CG-ND2 3.35Å; E124-N128 VanDerWaalsContact O-CB 3.27Å; E124-N128 WeakPolarHBondContact O-CB 3.47Å; E124-N128 PolarHBondContact O-N 2.88Å; E124-N128 PolarHBondContact O-ND2 2.85Å; E124-N128 VanDerWaalsContact O-ND2 3.15Å; E124-Y157 HydrophobicContact CB-CD1 3.94Å; E124-Y157 HydrophobicContact CB-CD2 3.98Å; E124-Y157 HydrophobicContact CB-CE1 3.81Å; E124-Y157 HydrophobicContact CB-CE2 3.91Å; E124-Y157 HydrophobicContact CB-CG 4.04Å; E124-Y157 HydrophobicContact CG-CD1 4.22Å; E124-Y157 HydrophobicContact CG-CD2 3.37Å; E124-Y157 HydrophobicContact CG-CE1 4.29Å; E124-Y157 HydrophobicContact CG-CE2 3.52Å; E124-Y157 HydrophobicContact CG-CG 3.79Å; E124-Y157 WeakPolarHBondContact OE1-CD2 3.4Å; E124-R160 IonicContact OE1-NH2 2.66Å
125S95.4Very high94.8Very high64 Ų6473.2 Ų73.245%0.44837%0.365SS..Hα-helixtrans-60.5-44.9-179.6-175.90000111.9Y121 E122 Y123 A129Y121-S125 WeakPolarHBondContact O-CB 3.45Å; Y121-S125 PolarHBondContact O-N 2.93Å; E122-S125 PolarHBondContact O-N 3.49Å; Y123-S125 VanDerWaalsContact C-N 3.32Å; Y123-S125 PolarHBondContact O-N 3.4Å; S125-A129 WeakPolarHBondContact O-CB 3.48Å; S125-A129 PolarHBondContact O-N 2.9Å; S125-A129 VanDerWaalsContact O-N 3.09Å
126R96.3Very high94.8Very high68 Ų6870 Ų7026%0.25735%0.353SS..Hα-helixtrans-65-51179.7-178.3176.562.672.51.3111.4E118 E122 Y123 E124 N128 A129 E130E118-R126 IonicContact OE1-CZ 2.72Å; E118-R126 IonicContact OE1-NE 3.87Å; E118-R126 PolarHBondContact OE1-NE 2.86Å; E118-R126 VanDerWaalsContact OE1-NE 3.09Å; E118-R126 IonicContact OE1-NH2 3.06Å; E118-R126 PolarHBondContact OE1-NH2 3.35Å; E118-R126 IonicContact OE2-NE 3.62Å; E118-R126 PolarHBondContact OE2-NE 2.67Å; E118-R126 VanDerWaalsContact OE2-NE 3.16Å; E122-R126 WeakPolarHBondContact O-CB 3.23Å; E122-R126 PolarHBondContact O-N 3.4Å; Y123-R126 PolarHBondContact O-N 3.15Å; E124-R126 PolarHBondContact O-N 2.72Å; R126-N128 VanDerWaalsContact C-N 3.31Å; R126-N128 PolarHBondContact O-N 3.36Å; R126-A129 WeakPolarHBondContact O-CB 3.44Å; R126-A129 PolarHBondContact O-N 2.83Å; R126-A129 VanDerWaalsContact O-N 3.09Å; R126-E130 WeakPolarHBondContact CG-OE1 3.48Å; R126-E130 IonicContact NH1-OE1 3.52Å; R126-E130 PolarHBondContact NH1-OE1 3.23Å; R126-E130 IonicContact NH1-OE2 3.39Å; R126-E130 PolarHBondContact NH1-OE2 3.37Å; R126-E130 VanDerWaalsContact NH1-OE2 3.14Å; R126-E130 WeakPolarHBondContact O-CG 3.47Å; R126-E130 PolarHBondContact O-N 3.47Å
127M95.6Very high94.8Very high9 Ų968.5 Ų68.54%0.04435%0.346CS..Hα-helixtrans-62.9-37.6-178.9-63.8-61.4-78.100112Y123 E130 K131 D132 Y157Y123-M127 HydrophobicContact CD1-CG 3.8Å; Y123-M127 HydrophobicContact CD2-CG 4.34Å; Y123-M127 HydrophobicContact CE1-CG 3.5Å; Y123-M127 HydrophobicContact CE1-SD 4.44Å; Y123-M127 HydrophobicContact CE2-CG 4.08Å; Y123-M127 HydrophobicContact CE2-SD 4.2Å; Y123-M127 HydrophobicContact CG-CG 4.21Å; Y123-M127 WeakPolarHBondContact O-CB 3.45Å; Y123-M127 WeakPolarHBondContact O-CG 3.28Å; Y123-M127 PolarHBondContact O-N 2.63Å; M127-E130 PolarHBondContact O-N 3.39Å; M127-K131 PolarHBondContact O-N 2.84Å; M127-K131 VanDerWaalsContact O-N 3.1Å; M127-D132 HydrophobicContact CE-CB 3.63Å; M127-D132 VanDerWaalsContact CE-CG 3.49Å; M127-D132 VanDerWaalsContact CE-OD2 3.24Å; M127-D132 WeakPolarHBondContact CE-OD2 3.43Å; M127-D132 PolarHBondContact O-N 3.07Å; M127-D132 VanDerWaalsContact O-N 3.09Å; M127-D132 HydrophobicContact SD-CB 4.3Å; M127-Y157 WeakPolarHBondContact CB-OH 3.42Å
128N93.4Very high94.8Very high87 Ų8761.7 Ų61.747%0.46532%0.317SS..Hα-helixtrans-64.4-40.5173.7-74.8-25.9000112.1E124 R126 K131E124-N128 WeakPolarHBondContact CG-ND2 3.35Å; E124-N128 VanDerWaalsContact O-CB 3.27Å; E124-N128 WeakPolarHBondContact O-CB 3.47Å; E124-N128 PolarHBondContact O-N 2.88Å; E124-N128 PolarHBondContact O-ND2 2.85Å; E124-N128 VanDerWaalsContact O-ND2 3.15Å; R126-N128 VanDerWaalsContact C-N 3.31Å; R126-N128 PolarHBondContact O-N 3.36Å; N128-K131 PolarHBondContact O-N 2.97Å
129A94.4Very high94.9Very high82 Ų8260.5 Ų60.568%0.67831%0.311SS*.Hα-helixtrans-68.1-38.6177.600000112.2S125 R126 K131S125-A129 WeakPolarHBondContact O-CB 3.48Å; S125-A129 PolarHBondContact O-N 2.9Å; S125-A129 VanDerWaalsContact O-N 3.09Å; R126-A129 WeakPolarHBondContact O-CB 3.44Å; R126-A129 PolarHBondContact O-N 2.83Å; R126-A129 VanDerWaalsContact O-N 3.09Å; A129-K131 PolarHBondContact O-N 3.35Å
130E93.5Very high95Very high109 Ų10958.2 Ų58.251%0.50930%0.297SS..Hα-helixtrans-72.5-11.6176.1-70.4171-172.300112.6R126 M127 D132R126-E130 WeakPolarHBondContact CG-OE1 3.48Å; R126-E130 IonicContact NH1-OE1 3.52Å; R126-E130 PolarHBondContact NH1-OE1 3.23Å; R126-E130 IonicContact NH1-OE2 3.39Å; R126-E130 PolarHBondContact NH1-OE2 3.37Å; R126-E130 VanDerWaalsContact NH1-OE2 3.14Å; R126-E130 WeakPolarHBondContact O-CG 3.47Å; R126-E130 PolarHBondContact O-N 3.47Å; M127-E130 PolarHBondContact O-N 3.39Å; E130-D132 HydrophobicContact CB-CB 4.44Å; E130-D132 PolarHBondContact O-N 2.77Å
131K90.1Very high95.1Very high182 Ų18257.9 Ų57.979%0.79129%0.294SS*.THydrogen-bonded Turntrans53.632-171-56.8179.1-178.8176.70111.9M127 N128 A129 S133M127-K131 PolarHBondContact O-N 2.84Å; M127-K131 VanDerWaalsContact O-N 3.1Å; N128-K131 PolarHBondContact O-N 2.97Å; A129-K131 PolarHBondContact O-N 3.35Å; K131-S133 PolarHBondContact O-N 3.07Å
132D85.7Confident95.2Very high74 Ų7450.7 Ų50.740%0.39627%0.268SS..  trans-73.3125.9175.9-167.6-14.1000108.6M127 E130 K134M127-D132 HydrophobicContact CE-CB 3.63Å; M127-D132 VanDerWaalsContact CE-CG 3.49Å; M127-D132 VanDerWaalsContact CE-OD2 3.24Å; M127-D132 WeakPolarHBondContact CE-OD2 3.43Å; M127-D132 PolarHBondContact O-N 3.07Å; M127-D132 VanDerWaalsContact O-N 3.09Å; M127-D132 HydrophobicContact SD-CB 4.3Å; E130-D132 HydrophobicContact CB-CB 4.44Å; E130-D132 PolarHBondContact O-N 2.77Å; D132-K134 VanDerWaalsContact OD1-CB 3.29Å; D132-K134 WeakPolarHBondContact OD1-CB 3.48Å; D132-K134 PolarHBondContact OD1-N 2.76Å
133S83.5Confident95.2Very high98 Ų9847.8 Ų47.869%0.68525%0.254SS*.  trans-108.919.1-178.755.10000112K131 K135K131-S133 PolarHBondContact O-N 3.07Å; S133-K135 PolarHBondContact O-N 2.85Å
134K93.9Very high95.1Very high49 Ų4948.8 Ų48.821%0.21326%0.259CS..  trans-50.7127.6178-173.3174.9-176.3-166.90111E86 D132 W136E86-K134 VanDerWaalsContact CD-NZ 3.35Å; E86-K134 IonicContact OE1-NZ 3.16Å; E86-K134 PolarHBondContact OE1-NZ 2.87Å; D132-K134 VanDerWaalsContact OD1-CB 3.29Å; D132-K134 WeakPolarHBondContact OD1-CB 3.48Å; D132-K134 PolarHBondContact OD1-N 2.76Å; K134-W136 HydrophobicContact CD-CH2 3.99Å; K134-W136 HydrophobicContact CD-CZ2 3.65Å; K134-W136 HydrophobicContact CG-CZ2 4.2Å
135K96.7Very high95.2Very high83 Ų8347.3 Ų47.336%0.36125%0.252SS..  trans-102.1156.4176-62-66.3-168.7153.30111.1S133 R160 L161 E163S133-K135 PolarHBondContact O-N 2.85Å; K135-R160 PolarHBondContact NZ-O 2.83Å; K135-L161 CarbonylContact C-O 3.56Å; K135-L161 WeakPolarHBondContact CA-O 3.44Å; K135-L161 WeakPolarHBondContact CD-O 3.35Å; K135-E163 HydrophobicContact CB-CG 3.67Å; K135-E163 WeakPolarHBondContact CB-OE1 3.38Å
136W98.6Very high95.1Very high0 Ų045.2 Ų45.20%023%0.234CC..EExtended strand (participates in β ladder)trans-126.3145.7-174.2-5790.3000111.2N55 I56 L57 E86 Y123 K134 I139 L161 E163 A166N55-W136 HydrophobicContact CB-CD2 4.49Å; N55-W136 HydrophobicContact CB-CE3 3.69Å; N55-W136 HydrophobicContact CB-CZ3 4.12Å; I56-W136 VanDerWaalsContact C-CE3 3.42Å; I56-W136 WeakPolarHBondContact O-CZ3 3.42Å; L57-W136 HydrophobicContact CB-CD2 3.63Å; L57-W136 HydrophobicContact CB-CE3 3.64Å; L57-W136 HydrophobicContact CB-CG 4.07Å; L57-W136 HydrophobicContact CB-CH2 4.22Å; L57-W136 HydrophobicContact CB-CZ2 4.27Å; L57-W136 HydrophobicContact CB-CZ3 3.95Å; L57-W136 HydrophobicContact CD1-CH2 3.85Å; L57-W136 HydrophobicContact CD1-CZ2 3.89Å; L57-W136 HydrophobicContact CD1-CZ3 4.34Å; L57-W136 HydrophobicContact CD2-CD2 4.28Å; L57-W136 HydrophobicContact CD2-CG 4.5Å; L57-W136 HydrophobicContact CD2-CZ2 4.15Å; L57-W136 HydrophobicContact CG-CD2 4.45Å; L57-W136 HydrophobicContact CG-CZ2 4.34Å; E86-W136 HydrophobicContact CB-CH2 3.62Å; E86-W136 HydrophobicContact CB-CZ3 4.05Å; E86-W136 VanDerWaalsContact CD-CH2 3.48Å; E86-W136 HydrophobicContact CG-CH2 3.53Å; E86-W136 HydrophobicContact CG-CZ3 3.94Å; Y123-W136 WeakPolarHBondContact OH-CZ2 3.27Å; K134-W136 HydrophobicContact CD-CH2 3.99Å; K134-W136 HydrophobicContact CD-CZ2 3.65Å; K134-W136 HydrophobicContact CG-CZ2 4.2Å; W136-I139 HydrophobicContact CB-CD1 3.94Å; W136-I139 HydrophobicContact CB-CG1 3.6Å; W136-I139 HydrophobicContact CG-CD1 4.17Å; W136-I139 HydrophobicContact CG-CG1 4.08Å; W136-L161 PolarHBondContact N-O 2.89Å; W136-E163 PolarHBondContact O-N 3.16Å; W136-A166 WeakPolarHBondContact O-CB 3.36Å
137D98.8Very high94.9Very high3 Ų346.2 Ų46.22%0.01624%0.239CC..EExtended strand (participates in β ladder)trans-90.8-25.8179.4-56.3-45.4000111I47 K51 I54 N55 A166 K167I47-D137 HydrophobicContact CB-CB 4.39Å; I47-D137 WeakPolarHBondContact CB-O 3.33Å; I47-D137 WeakPolarHBondContact CG2-O 3.27Å; K51-D137 IonicContact NZ-OD1 2.76Å; K51-D137 PolarHBondContact NZ-OD1 3.07Å; I54-D137 VanDerWaalsContact CA-OD2 3.3Å; I54-D137 WeakPolarHBondContact CA-OD2 3.29Å; I54-D137 HydrophobicContact CG2-CB 3.9Å; N55-D137 PolarHBondContact N-OD2 2.61Å; N55-D137 WeakPolarHBondContact O-CB 3.19Å; N55-D137 PolarHBondContact O-N 2.93Å; D137-A166 WeakPolarHBondContact O-CA 3.32Å; D137-A166 VanDerWaalsContact O-CB 3.23Å; D137-A166 WeakPolarHBondContact O-CB 3.48Å; D137-K167 PolarHBondContact O-N 2.78Å
138F98.9Very high94.8Very high1 Ų146.4 Ų46.40%0.00424%0.241CC..EExtended strand (participates in β ladder)trans-149.9130173.3-174.2-129.8000109.5L40 I44 I47 N55 I56 L57 M70 H140 K167 L169L40-F138 HydrophobicContact CD1-CZ 4.15Å; I44-F138 HydrophobicContact CG2-CD2 4.48Å; I44-F138 HydrophobicContact CG2-CE2 4.35Å; I47-F138 HydrophobicContact CD1-CB 3.9Å; I47-F138 HydrophobicContact CD1-CG 4.46Å; N55-F138 PolarHBondContact O-N 3.05Å; I56-F138 CarbonylContact C-O 3.57Å; I56-F138 VanDerWaalsContact CA-O 3.27Å; I56-F138 WeakPolarHBondContact CA-O 3.47Å; I56-F138 HydrophobicContact CG1-CB 4.18Å; I56-F138 HydrophobicContact CG2-CB 4.41Å; I56-F138 HydrophobicContact CG2-CD1 3.89Å; L57-F138 PolarHBondContact N-O 3.44Å; M70-F138 HydrophobicContact SD-CE1 3.99Å; M70-F138 HydrophobicContact SD-CZ 4.17Å; F138-H140 HydrophobicContact CE1-CB 4.18Å; F138-H140 AromaticContact CE1-CD2 3.71Å; F138-H140 HydrophobicContact CZ-CB 4.11Å; F138-K167 WeakPolarHBondContact CA-O 3.3Å; F138-K167 HydrophobicContact CD2-CB 4.06Å; F138-K167 WeakPolarHBondContact CD2-O 3.24Å; F138-K167 HydrophobicContact CE2-CB 4.34Å; F138-L169 HydrophobicContact CE2-CB 3.71Å; F138-L169 HydrophobicContact CE2-CD1 4.37Å; F138-L169 HydrophobicContact CZ-CB 3.88Å; F138-L169 HydrophobicContact CZ-CD1 4.11Å; F138-L169 HydrophobicContact CZ-CG 4.49Å
139I98.9Very high94.6Very high0 Ų050.2 Ų50.20%025%0.253CS..EExtended strand (participates in β ladder)trans-121.3137.2171.5-53.9179.5000106.8L57 V59 W136 F158 L161 L162 K167 L168 L169L57-I139 HydrophobicContact CB-CG1 4.14Å; L57-I139 HydrophobicContact CB-CG2 4.28Å; L57-I139 HydrophobicContact CD2-CG2 4.47Å; L57-I139 VanDerWaalsContact O-CA 3.31Å; L57-I139 WeakPolarHBondContact O-CA 3.25Å; V59-I139 HydrophobicContact CG2-CG2 4Å; W136-I139 HydrophobicContact CB-CD1 3.94Å; W136-I139 HydrophobicContact CB-CG1 3.6Å; W136-I139 HydrophobicContact CG-CD1 4.17Å; W136-I139 HydrophobicContact CG-CG1 4.08Å; I139-F158 HydrophobicContact CD1-CB 4.32Å; I139-F158 HydrophobicContact CD1-CD1 4.49Å; I139-F158 VanDerWaalsContact CD1-O 3.23Å; I139-F158 WeakPolarHBondContact CD1-O 3.49Å; I139-F158 HydrophobicContact CG2-CB 4.4Å; I139-F158 HydrophobicContact CG2-CD1 4.22Å; I139-L161 HydrophobicContact CD1-CB 4.09Å; I139-L162 HydrophobicContact CB-CD2 4.41Å; I139-L162 HydrophobicContact CD1-CD2 3.79Å; I139-L162 HydrophobicContact CD1-CG 4.43Å; I139-L162 HydrophobicContact CG1-CD2 3.89Å; I139-K167 PolarHBondContact N-O 3.21Å; I139-L168 HydrophobicContact CB-CD1 3.73Å; I139-L168 HydrophobicContact CG2-CD1 3.59Å; I139-L168 CarbonylContact O-C 3.51Å; I139-L168 WeakPolarHBondContact O-CA 3.36Å; I139-L169 PolarHBondContact O-N 2.68Å
140H98.9Very high94.6Very high3 Ų350.3 Ų50.31%0.01424%0.242CC..EExtended strand (participates in β ladder)trans-134.1143.9173.163.683.5000113.2L57 S58 V59 D67 M70 F138 L169L57-H140 PolarHBondContact O-N 3.47Å; S58-H140 VanDerWaalsContact CA-CE1 3.48Å; S58-H140 WeakPolarHBondContact CA-CE1 3.2Å; S58-H140 WeakPolarHBondContact CB-CE1 3.4Å; S58-H140 WeakPolarHBondContact CB-NE2 3.27Å; S58-H140 PolarHBondContact OG-CE1 3.35Å; V59-H140 PolarHBondContact N-O 2.83Å; D67-H140 IonicContact OD1-CE1 2.68Å; D67-H140 IonicContact OD1-NE2 2.61Å; D67-H140 IonicContact OD2-CE1 3.4Å; M70-H140 HydrophobicContact CE-CB 4.27Å; M70-H140 WeakPolarHBondContact CE-CE1 3.42Å; M70-H140 WeakPolarHBondContact CE-ND1 3.49Å; M70-H140 WeakPolarHBondContact CE-NE2 3.49Å; M70-H140 HydrophobicContact SD-CB 4.48Å; F138-H140 HydrophobicContact CE1-CB 4.18Å; F138-H140 AromaticContact CE1-CD2 3.71Å; F138-H140 HydrophobicContact CZ-CB 4.11Å; H140-L169 CarbonylContact C-O 3.57Å; H140-L169 WeakPolarHBondContact CA-O 3.41Å; H140-L169 HydrophobicContact CB-CB 4.25Å; H140-L169 HydrophobicContact CB-CD2 4.12Å
141M98.8Very high94.7Very high0 Ų045.9 Ų45.90%022%0.222CC..EExtended strand (participates in β ladder)trans-128.395.5178.7-60.7176.5-178.800108.3V59 M144 L145 T154 F158 L168 L169 I170 I171V59-M141 HydrophobicContact CB-CG 4.02Å; V59-M141 HydrophobicContact CG2-CE 4.3Å; V59-M141 HydrophobicContact CG2-CG 4.15Å; M141-M144 HydrophobicContact CB-CG 4.07Å; M141-M144 HydrophobicContact CB-SD 3.89Å; M141-M144 HydrophobicContact CG-SD 4.14Å; M141-L145 HydrophobicContact SD-CD2 3.84Å; M141-L145 HydrophobicContact SD-CG 4.38Å; M141-T154 HydrophobicContact CE-CG2 4.48Å; M141-F158 HydrophobicContact CE-CB 3.4Å; M141-F158 HydrophobicContact CE-CD1 4.23Å; M141-F158 HydrophobicContact CE-CD2 3.1Å; M141-F158 HydrophobicContact CE-CE2 3.9Å; M141-F158 HydrophobicContact CE-CG 3.3Å; M141-L168 HydrophobicContact CE-CD1 4.02Å; M141-L168 HydrophobicContact CG-CD1 4.35Å; M141-L168 HydrophobicContact SD-CD1 4.33Å; M141-L169 PolarHBondContact N-O 2.96Å; M141-I170 HydrophobicContact CB-CG1 4.32Å; M141-I170 WeakPolarHBondContact O-CA 3.38Å; M141-I170 HydrophobicContact SD-CD1 4.47Å; M141-I170 HydrophobicContact SD-CG1 4.31Å; M141-I171 PolarHBondContact O-N 3.32Å
142V98.3Very high95Very high19 Ų1939.3 Ų39.312%0.11520%0.198CC..EExtended strand (participates in β ladder)trans-103117.1-175179.80000109.2M32 I66 M70 M144 I171M32-V142 HydrophobicContact CE-CG1 4.09Å; M32-V142 HydrophobicContact SD-CG1 3.89Å; I66-V142 HydrophobicContact CG2-CG1 4.37Å; I66-V142 HydrophobicContact CG2-CG2 4.22Å; M70-V142 HydrophobicContact CE-CG2 4.44Å; V142-M144 PolarHBondContact O-N 3.09Å; V142-M144 VanDerWaalsContact O-N 3.07Å; V142-I171 HydrophobicContact CG1-CB 4.19Å; V142-I171 HydrophobicContact CG1-CD1 4.28Å; V142-I171 HydrophobicContact CG2-CB 4.49Å; V142-I171 HydrophobicContact CG2-CD1 4.05Å; V142-I171 HydrophobicContact CG2-CG1 4.11Å
143Q96.3Very high95.6Very high38 Ų3836.8 Ų36.818%0.17819%0.187CC..SBendtrans51.333.8173.7-62.5-69.435.600115.5E28 M32 Y146 I171 L285E28-Q143 WeakPolarHBondContact OE1-CG 2.95Å; E28-Q143 PolarHBondContact OE1-NE2 3.19Å; M32-Q143 HydrophobicContact CE-CG 3.62Å; Q143-Y146 HydrophobicContact CB-CE2 4.25Å; Q143-Y146 WeakPolarHBondContact O-CD2 3.41Å; Q143-Y146 VanDerWaalsContact OE1-CZ 3.29Å; Q143-Y146 PolarHBondContact OE1-OH 2.84Å; Q143-I171 PolarHBondContact N-O 3.43Å; Q143-L285 VanDerWaalsContact NE2-CD2 3.33Å
144M95.9Very high96.2Very high21 Ų2132.6 Ų32.610%0.10316%0.157CC..  trans-124.4-15.2-171.665.580.26200115.1V59 A120 M141 V142 Y146 Y147 V148V59-M144 HydrophobicContact CB-CE 4.15Å; V59-M144 HydrophobicContact CG1-CE 3.44Å; V59-M144 VanDerWaalsContact CG1-CE 3.44Å; V59-M144 HydrophobicContact CG1-SD 4.34Å; V59-M144 WeakPolarHBondContact O-CG 3.48Å; A120-M144 HydrophobicContact CB-CE 4.32Å; M141-M144 HydrophobicContact CB-CG 4.07Å; M141-M144 HydrophobicContact CB-SD 3.89Å; M141-M144 HydrophobicContact CG-SD 4.14Å; V142-M144 PolarHBondContact O-N 3.09Å; V142-M144 VanDerWaalsContact O-N 3.07Å; M144-Y146 PolarHBondContact O-N 3.18Å; M144-Y147 WeakPolarHBondContact O-CD2 3.33Å; M144-Y147 PolarHBondContact O-N 3.49Å; M144-Y147 VanDerWaalsContact O-N 3.09Å; M144-V148 HydrophobicContact CE-CG2 4.23Å; M144-V148 HydrophobicContact SD-CG2 4.41Å
145L96.9Very high96.4Very high3 Ų330.3 Ų30.32%0.01615%0.147CC..G310 helixtrans-67.1-18.1-177.4-74.5-179.4000113.3M141 Y147 V148 I151 T154 I155 I170 I199 I204M141-L145 HydrophobicContact SD-CD2 3.84Å; M141-L145 HydrophobicContact SD-CG 4.38Å; L145-Y147 PolarHBondContact O-N 3.02Å; L145-V148 HydrophobicContact CD2-CG2 4.17Å; L145-V148 PolarHBondContact O-N 2.84Å; L145-I151 HydrophobicContact CD1-CG2 4.4Å; L145-T154 HydrophobicContact CD2-CG2 4.5Å; L145-I155 HydrophobicContact CD1-CD1 4.33Å; L145-I170 HydrophobicContact CD1-CD1 4.14Å; L145-I170 HydrophobicContact CD1-CG2 3.51Å; L145-I170 HydrophobicContact CG-CG2 4.43Å; L145-I199 HydrophobicContact CB-CD1 3.61Å; L145-I204 HydrophobicContact CD1-CD1 3.99Å
146Y94Very high96.5Very high20 Ų2032.3 Ų32.38%0.07815%0.153CC..G310 helixtrans-57.1-28.9171.8-44.2-69000112.4Q143 M144 L172 V173 W183 C196 F197 I199Q143-Y146 HydrophobicContact CB-CE2 4.25Å; Q143-Y146 WeakPolarHBondContact O-CD2 3.41Å; Q143-Y146 VanDerWaalsContact OE1-CZ 3.29Å; Q143-Y146 PolarHBondContact OE1-OH 2.84Å; M144-Y146 PolarHBondContact O-N 3.18Å; Y146-L172 WeakPolarHBondContact OH-CA 3.27Å; Y146-L172 WeakPolarHBondContact OH-CB 3.28Å; Y146-V173 HydrophobicContact CE1-CG2 4.27Å; Y146-V173 PolarHBondContact OH-N 3.35Å; Y146-W183 HydrophobicContact CE1-CH2 4.13Å; Y146-C196 CarbonylContact O-C 3.54Å; Y146-C196 VanDerWaalsContact O-CA 3.29Å; Y146-C196 WeakPolarHBondContact O-CA 3.28Å; Y146-F197 WeakPolarHBondContact O-CD2 3.37Å; Y146-F197 PolarHBondContact O-N 3.22Å; Y146-I199 HydrophobicContact CD1-CD1 4.33Å; Y146-I199 HydrophobicContact CD1-CG1 3.69Å; Y146-I199 HydrophobicContact CE1-CG1 3.98Å; Y146-I199 WeakPolarHBondContact CE1-O 3.41Å
147Y92.4Very high96.4Very high90 Ų9032.6 Ų32.635%0.35315%0.154SC..G310 helixtrans-99.515.2-174.4-46.1-65.8000112.8I9 Y15 M144 L145I9-Y147 HydrophobicContact CD1-CD1 4.43Å; I9-Y147 HydrophobicContact CD1-CE1 3.99Å; Y15-Y147 PolarHBondContact OH-OH 3.3Å; M144-Y147 WeakPolarHBondContact O-CD2 3.33Å; M144-Y147 PolarHBondContact O-N 3.49Å; M144-Y147 VanDerWaalsContact O-N 3.09Å; L145-Y147 PolarHBondContact O-N 3.02Å
148V92.6Very high96.4Very high13 Ų1332.4 Ų32.48%0.07915%0.153CC..  trans-109.4127.9-177.8174.30000109.9M144 L145 I151 T154 F197M144-V148 HydrophobicContact CE-CG2 4.23Å; M144-V148 HydrophobicContact SD-CG2 4.41Å; L145-V148 HydrophobicContact CD2-CG2 4.17Å; L145-V148 PolarHBondContact O-N 2.84Å; V148-I151 HydrophobicContact CB-CG1 4.26Å; V148-I151 HydrophobicContact CG1-CG1 4.29Å; V148-T154 HydrophobicContact CG1-CG2 3.98Å; V148-T154 WeakPolarHBondContact CG1-OG1 3.45Å; V148-F197 WeakPolarHBondContact O-CD2 3.39Å; V148-F197 WeakPolarHBondContact O-CE2 3.44Å
149K89.2Confident96.4Very high167 Ų16733.5 Ų33.573%0.72616%0.158SC*.SBendtrans-71.6-42.9-176.5-171.8173.3-176.3170.30114.2
150D94.3Very high96.3Very high84 Ų8440.1 Ų40.145%0.44918%0.183SC..  trans-120.485.6178.1-170.2-24.4000109.1P152 A153 T154D150-P152 WeakPolarHBondContact OD1-CD 3.35Å; D150-A153 HydrophobicContact CB-CB 3.96Å; D150-A153 PolarHBondContact O-N 2.9Å; D150-A153 VanDerWaalsContact OD1-CB 3.23Å; D150-A153 WeakPolarHBondContact OD1-CB 3.29Å; D150-A153 PolarHBondContact OD1-N 3.06Å; D150-A153 WeakPolarHBondContact OD2-CB 3.47Å; D150-T154 WeakPolarHBondContact O-CB 3.47Å; D150-T154 PolarHBondContact O-N 2.91Å; D150-T154 PolarHBondContact O-OG1 3.13Å
151I96Very high96.2Very high16 Ų1640.9 Ų40.98%0.08219%0.187CC..Hα-helixtrans-61.7-47.8-178-62.2153.2000111.2L145 V148 A153 T154 I155 I199 I204 I207L145-I151 HydrophobicContact CD1-CG2 4.4Å; V148-I151 HydrophobicContact CB-CG1 4.26Å; V148-I151 HydrophobicContact CG1-CG1 4.29Å; I151-A153 PolarHBondContact O-N 3.31Å; I151-T154 PolarHBondContact O-N 3.23Å; I151-I155 HydrophobicContact CG2-CD1 3.78Å; I151-I155 HydrophobicContact CG2-CG1 4.34Å; I151-I155 WeakPolarHBondContact O-CG1 3.35Å; I151-I155 PolarHBondContact O-N 3.05Å; I151-I199 HydrophobicContact CD1-CD1 3.51Å; I151-I199 HydrophobicContact CD1-CG1 4.44Å; I151-I199 HydrophobicContact CD1-CG2 3.66Å; I151-I199 HydrophobicContact CG1-CD1 4.28Å; I151-I204 HydrophobicContact CG2-CD1 3.6Å; I151-I207 HydrophobicContact CG2-CD1 4.02Å
152P97.1Very high96.2Very high43 Ų4341.4 Ų41.428%0.27919%0.19SC..Hα-helixtrans-57.9-43.2175.8-24.833.9000113.5D150 R156 I207D150-P152 WeakPolarHBondContact OD1-CD 3.35Å; P152-R156 WeakPolarHBondContact O-CB 3.48Å; P152-R156 VanDerWaalsContact O-CG 3.31Å; P152-R156 WeakPolarHBondContact O-CG 3.42Å; P152-R156 PolarHBondContact O-N 2.87Å; P152-I207 HydrophobicContact CB-CG2 4.06Å; P152-I207 HydrophobicContact CG-CD1 3.92Å; P152-I207 HydrophobicContact CG-CG1 4.15Å; P152-I207 HydrophobicContact CG-CG2 4.25Å
153A96.9Very high96.2Very high22 Ų2244.1 Ų44.118%0.18220%0.201CC..Hα-helixtrans-65.6-41.7177.300000111.9D150 I151 R156 Y157D150-A153 HydrophobicContact CB-CB 3.96Å; D150-A153 PolarHBondContact O-N 2.9Å; D150-A153 VanDerWaalsContact OD1-CB 3.23Å; D150-A153 WeakPolarHBondContact OD1-CB 3.29Å; D150-A153 PolarHBondContact OD1-N 3.06Å; D150-A153 WeakPolarHBondContact OD2-CB 3.47Å; I151-A153 PolarHBondContact O-N 3.31Å; A153-R156 VanDerWaalsContact CA-NH2 3.34Å; A153-R156 PolarHBondContact O-N 3.4Å; A153-Y157 WeakPolarHBondContact O-CB 3.12Å; A153-Y157 PolarHBondContact O-N 3.11Å
154T97.6Very high96.1Very high9 Ų946.4 Ų46.46%0.05523%0.227CC..Hα-helixtrans-62.4-49.6179.1-600000111.2A120 M141 L145 V148 D150 I151 R156 Y157 F158A120-T154 HydrophobicContact CB-CG2 4.44Å; M141-T154 HydrophobicContact CE-CG2 4.48Å; L145-T154 HydrophobicContact CD2-CG2 4.5Å; V148-T154 HydrophobicContact CG1-CG2 3.98Å; V148-T154 WeakPolarHBondContact CG1-OG1 3.45Å; D150-T154 WeakPolarHBondContact O-CB 3.47Å; D150-T154 PolarHBondContact O-N 2.91Å; D150-T154 PolarHBondContact O-OG1 3.13Å; I151-T154 PolarHBondContact O-N 3.23Å; T154-R156 VanDerWaalsContact C-N 3.33Å; T154-R156 PolarHBondContact O-N 2.93Å; T154-Y157 PolarHBondContact O-N 3.4Å; T154-Y157 VanDerWaalsContact O-N 3.11Å; T154-F158 HydrophobicContact CG2-CD2 3.77Å; T154-F158 HydrophobicContact CG2-CE2 3.72Å; T154-F158 VanDerWaalsContact O-CD2 3.27Å; T154-F158 WeakPolarHBondContact O-CD2 3.36Å; T154-F158 PolarHBondContact O-N 3.39Å
155I98.1Very high96.1Very high1 Ų149.4 Ų49.41%0.00524%0.24CC..Hα-helixtrans-58.8-46176.4-68.8173.6000110.4L145 I151 Y157 F158 H159 I170 I204 L208 I290L145-I155 HydrophobicContact CD1-CD1 4.33Å; I151-I155 HydrophobicContact CG2-CD1 3.78Å; I151-I155 HydrophobicContact CG2-CG1 4.34Å; I151-I155 WeakPolarHBondContact O-CG1 3.35Å; I151-I155 PolarHBondContact O-N 3.05Å; I155-Y157 VanDerWaalsContact C-N 3.32Å; I155-Y157 PolarHBondContact O-N 3.03Å; I155-F158 PolarHBondContact O-N 3.37Å; I155-H159 WeakPolarHBondContact O-CB 3.23Å; I155-H159 PolarHBondContact O-N 2.81Å; I155-I170 HydrophobicContact CD1-CD1 4.05Å; I155-I170 HydrophobicContact CG1-CD1 4.13Å; I155-I204 HydrophobicContact CD1-CD1 4.06Å; I155-I204 HydrophobicContact CD1-CG2 4Å; I155-L208 HydrophobicContact CG2-CD2 3.76Å; I155-I290 HydrophobicContact CG2-CD1 4.44Å
156R97.6Very high96.1Very high126 Ų12649.2 Ų49.248%0.47524%0.24SC..Hα-helixtrans-60.6-40.6175.6-76.1-169.9-53.7-93.4-0.7112.3P152 A153 T154 R160P152-R156 WeakPolarHBondContact O-CB 3.48Å; P152-R156 VanDerWaalsContact O-CG 3.31Å; P152-R156 WeakPolarHBondContact O-CG 3.42Å; P152-R156 PolarHBondContact O-N 2.87Å; A153-R156 VanDerWaalsContact CA-NH2 3.34Å; A153-R156 PolarHBondContact O-N 3.4Å; T154-R156 VanDerWaalsContact C-N 3.33Å; T154-R156 PolarHBondContact O-N 2.93Å; R156-R160 VanDerWaalsContact O-CG 3.23Å; R156-R160 WeakPolarHBondContact O-CG 3.44Å; R156-R160 PolarHBondContact O-N 3Å; R156-R160 VanDerWaalsContact O-N 3.15Å; R156-R160 PolarHBondContact O-NE 3.3Å
157Y97.5Very high96.4Very high5 Ų549.3 Ų49.32%0.0224%0.24CC..Hα-helixtrans-60.5-56.3179.5171.9-96.4000110.5Y123 E124 M127 A153 T154 I155 H159 R160 L161Y123-Y157 HydrophobicContact CD1-CE1 4.2Å; Y123-Y157 HydrophobicContact CE1-CE1 4.36Å; E124-Y157 HydrophobicContact CB-CD1 3.94Å; E124-Y157 HydrophobicContact CB-CD2 3.98Å; E124-Y157 HydrophobicContact CB-CE1 3.81Å; E124-Y157 HydrophobicContact CB-CE2 3.91Å; E124-Y157 HydrophobicContact CB-CG 4.04Å; E124-Y157 HydrophobicContact CG-CD1 4.22Å; E124-Y157 HydrophobicContact CG-CD2 3.37Å; E124-Y157 HydrophobicContact CG-CE1 4.29Å; E124-Y157 HydrophobicContact CG-CE2 3.52Å; E124-Y157 HydrophobicContact CG-CG 3.79Å; E124-Y157 WeakPolarHBondContact OE1-CD2 3.4Å; M127-Y157 WeakPolarHBondContact CB-OH 3.42Å; A153-Y157 WeakPolarHBondContact O-CB 3.12Å; A153-Y157 PolarHBondContact O-N 3.11Å; T154-Y157 PolarHBondContact O-N 3.4Å; T154-Y157 VanDerWaalsContact O-N 3.11Å; I155-Y157 VanDerWaalsContact C-N 3.32Å; I155-Y157 PolarHBondContact O-N 3.03Å; Y157-H159 PolarHBondContact O-N 2.97Å; Y157-R160 PolarHBondContact O-N 3.06Å; Y157-L161 HydrophobicContact CD1-CD1 4.32Å; Y157-L161 HydrophobicContact CE1-CD1 3.63Å; Y157-L161 HydrophobicContact CE1-CG 4.41Å
158F98.2Very high96.7Very high0 Ų045 Ų450%022%0.224CC..Hα-helixtrans-69-34.5-177.2-73-75.4000112.8L57 V59 I88 A120 Y123 I139 M141 T154 I155 R160 L161L57-F158 HydrophobicContact CD2-CD1 3.82Å; L57-F158 HydrophobicContact CD2-CE1 3.63Å; V59-F158 HydrophobicContact CG1-CE2 4.24Å; V59-F158 HydrophobicContact CG1-CZ 3.91Å; V59-F158 HydrophobicContact CG2-CD1 4.06Å; V59-F158 HydrophobicContact CG2-CE1 3.72Å; V59-F158 HydrophobicContact CG2-CE2 4.46Å; V59-F158 HydrophobicContact CG2-CZ 3.94Å; I88-F158 HydrophobicContact CD1-CE1 3.92Å; I88-F158 HydrophobicContact CD1-CZ 3.98Å; A120-F158 HydrophobicContact CB-CE2 3.93Å; A120-F158 HydrophobicContact CB-CZ 4.1Å; Y123-F158 HydrophobicContact CD1-CE1 4.25Å; Y123-F158 HydrophobicContact CD1-CZ 4.36Å; Y123-F158 HydrophobicContact CE1-CE1 4.32Å; I139-F158 HydrophobicContact CD1-CB 4.32Å; I139-F158 HydrophobicContact CD1-CD1 4.49Å; I139-F158 VanDerWaalsContact CD1-O 3.23Å; I139-F158 WeakPolarHBondContact CD1-O 3.49Å; I139-F158 HydrophobicContact CG2-CB 4.4Å; I139-F158 HydrophobicContact CG2-CD1 4.22Å; M141-F158 HydrophobicContact CE-CB 3.4Å; M141-F158 HydrophobicContact CE-CD1 4.23Å; M141-F158 HydrophobicContact CE-CD2 3.1Å; M141-F158 HydrophobicContact CE-CE2 3.9Å; M141-F158 HydrophobicContact CE-CG 3.3Å; T154-F158 HydrophobicContact CG2-CD2 3.77Å; T154-F158 HydrophobicContact CG2-CE2 3.72Å; T154-F158 VanDerWaalsContact O-CD2 3.27Å; T154-F158 WeakPolarHBondContact O-CD2 3.36Å; T154-F158 PolarHBondContact O-N 3.39Å; I155-F158 PolarHBondContact O-N 3.37Å; F158-R160 VanDerWaalsContact C-N 3.32Å; F158-R160 PolarHBondContact O-N 2.91Å; F158-L161 HydrophobicContact CD1-CD1 4.13Å; F158-L161 WeakPolarHBondContact O-CB 3.31Å; F158-L161 PolarHBondContact O-N 2.94Å
159H98.3Very high97Very high23 Ų2344.4 Ų44.411%0.10622%0.22CC..Hα-helixtrans-57-44.1172.2177.1-91.7000111.9I155 Y157 L161 L162 L168 E291 P292I155-H159 WeakPolarHBondContact O-CB 3.23Å; I155-H159 PolarHBondContact O-N 2.81Å; Y157-H159 PolarHBondContact O-N 2.97Å; H159-L161 PolarHBondContact O-N 3.45Å; H159-L161 VanDerWaalsContact O-N 3.08Å; H159-L162 VanDerWaalsContact O-CB 3.29Å; H159-L162 WeakPolarHBondContact O-CB 3.45Å; H159-L162 VanDerWaalsContact O-CG 3.27Å; H159-L162 WeakPolarHBondContact O-CG 3.17Å; H159-L162 PolarHBondContact O-N 3.42Å; H159-L168 HydrophobicContact CB-CD2 4.44Å; H159-E291 PolarHBondContact CD2-O 2.68Å; H159-E291 PolarHBondContact NE2-O 2.88Å; H159-P292 PolarHBondContact CE1-OXT 3.34Å; H159-P292 PolarHBondContact NE2-OXT 2.85Å; H159-P292 VanDerWaalsContact NE2-OXT 3.13Å
160R97.1Very high97.4Very high139 Ų13936.5 Ų36.553%0.52519%0.185SC..THydrogen-bonded Turntrans-63.4-16.7176.7-69.1175-50.4178.45.7113.7E124 K135 R156 Y157 F158 L162E124-R160 IonicContact OE1-NH2 2.66Å; K135-R160 PolarHBondContact NZ-O 2.83Å; R156-R160 VanDerWaalsContact O-CG 3.23Å; R156-R160 WeakPolarHBondContact O-CG 3.44Å; R156-R160 PolarHBondContact O-N 3Å; R156-R160 VanDerWaalsContact O-N 3.15Å; R156-R160 PolarHBondContact O-NE 3.3Å; Y157-R160 PolarHBondContact O-N 3.06Å; F158-R160 VanDerWaalsContact C-N 3.32Å; F158-R160 PolarHBondContact O-N 2.91Å; R160-L162 VanDerWaalsContact C-N 3.32Å
161L97.9Very high97.6Very high20 Ų2032.6 Ų32.611%0.10517%0.165CC..THydrogen-bonded Turntrans-87.4-1.6177.9-51.4-179.7000112.9K135 W136 I139 Y157 F158 H159K135-L161 CarbonylContact C-O 3.56Å; K135-L161 WeakPolarHBondContact CA-O 3.44Å; K135-L161 WeakPolarHBondContact CD-O 3.35Å; W136-L161 PolarHBondContact N-O 2.89Å; I139-L161 HydrophobicContact CD1-CB 4.09Å; Y157-L161 HydrophobicContact CD1-CD1 4.32Å; Y157-L161 HydrophobicContact CE1-CD1 3.63Å; Y157-L161 HydrophobicContact CE1-CG 4.41Å; F158-L161 HydrophobicContact CD1-CD1 4.13Å; F158-L161 WeakPolarHBondContact O-CB 3.31Å; F158-L161 PolarHBondContact O-N 2.94Å; H159-L161 PolarHBondContact O-N 3.45Å; H159-L161 VanDerWaalsContact O-N 3.08Å
162L98.4Very high97.7Very high11 Ų1132 Ų326%0.05816%0.161CC..EExtended strand (participates in β ladder)trans-70.7140.2179.2-65.6176.6000112.3I139 H159 R160 A166 L168 P292I139-L162 HydrophobicContact CB-CD2 4.41Å; I139-L162 HydrophobicContact CD1-CD2 3.79Å; I139-L162 HydrophobicContact CD1-CG 4.43Å; I139-L162 HydrophobicContact CG1-CD2 3.89Å; H159-L162 VanDerWaalsContact O-CB 3.29Å; H159-L162 WeakPolarHBondContact O-CB 3.45Å; H159-L162 VanDerWaalsContact O-CG 3.27Å; H159-L162 WeakPolarHBondContact O-CG 3.17Å; H159-L162 PolarHBondContact O-N 3.42Å; R160-L162 VanDerWaalsContact C-N 3.32Å; L162-A166 HydrophobicContact CB-CB 3.98Å; L162-A166 HydrophobicContact CD2-CB 3.77Å; L162-A166 HydrophobicContact CG-CB 4.44Å; L162-L168 HydrophobicContact CD1-CB 3.87Å; L162-L168 HydrophobicContact CD2-CB 4.14Å; L162-L168 HydrophobicContact CG-CB 4.47Å; L162-P292 HydrophobicContact CB-CB 3.88Å; L162-P292 HydrophobicContact CD1-CB 4.33Å
163E97.4Very high97.8Very high75 Ų7530.2 Ų30.235%0.3515%0.15SC..EExtended strand (participates in β ladder)trans-74.8164.9163.1-84.9-60.616600112K135 W136 Q165 A166 P292K135-E163 HydrophobicContact CB-CG 3.67Å; K135-E163 WeakPolarHBondContact CB-OE1 3.38Å; W136-E163 PolarHBondContact O-N 3.16Å; E163-Q165 PolarHBondContact O-N 2.94Å; E163-A166 HydrophobicContact CB-CB 4.05Å; E163-A166 VanDerWaalsContact O-CB 3.23Å; E163-A166 WeakPolarHBondContact O-CB 3.35Å; E163-A166 PolarHBondContact O-N 3.42Å; E163-P292 VanDerWaalsContact O-CB 3.27Å; E163-P292 WeakPolarHBondContact O-CB 3.45Å
164A94.4Very high97.8Very high86 Ų8629.2 Ų29.271%0.71114%0.141SC*.EExtended strand (participates in β ladder)trans-58.7-20.5-174.300000116.3P292A164-P292 WeakPolarHBondContact O-CG 3.16Å
165Q95.6Very high97.8Very high84 Ų8429.9 Ų29.939%0.39315%0.15SC..EExtended strand (participates in β ladder)trans-119.69.9177.1-66.5-175.2-3500112.7S46 E163S46-Q165 PolarHBondContact O-OE1 3.45Å; E163-Q165 PolarHBondContact O-N 2.94Å
166A98.3Very high97.7Very high0 Ų033.1 Ų33.10%018%0.177CC..EExtended strand (participates in β ladder)trans-74.1171.9-17600000111.9W136 D137 L162 E163 P292W136-A166 WeakPolarHBondContact O-CB 3.36Å; D137-A166 WeakPolarHBondContact O-CA 3.32Å; D137-A166 VanDerWaalsContact O-CB 3.23Å; D137-A166 WeakPolarHBondContact O-CB 3.48Å; L162-A166 HydrophobicContact CB-CB 3.98Å; L162-A166 HydrophobicContact CD2-CB 3.77Å; L162-A166 HydrophobicContact CG-CB 4.44Å; E163-A166 HydrophobicContact CB-CB 4.05Å; E163-A166 VanDerWaalsContact O-CB 3.23Å; E163-A166 WeakPolarHBondContact O-CB 3.35Å; E163-A166 PolarHBondContact O-N 3.42Å; A166-P292 WeakPolarHBondContact O-CD 3.39Å
167K98.6Very high97.7Very high22 Ų2227.2 Ų27.210%0.09616%0.155CC..EExtended strand (participates in β ladder)trans-133.3142.5171.3-54.8-68.2173.7-174.30109.6V43 I47 D137 F138 I139 V289 E291V43-K167 HydrophobicContact CG1-CB 4.4Å; V43-K167 HydrophobicContact CG1-CG 4.09Å; I47-K167 HydrophobicContact CG2-CG 4.04Å; D137-K167 PolarHBondContact O-N 2.78Å; F138-K167 WeakPolarHBondContact CA-O 3.3Å; F138-K167 HydrophobicContact CD2-CB 4.06Å; F138-K167 WeakPolarHBondContact CD2-O 3.24Å; F138-K167 HydrophobicContact CE2-CB 4.34Å; I139-K167 PolarHBondContact N-O 3.21Å; K167-V289 HydrophobicContact CB-CG1 4.33Å; K167-V289 HydrophobicContact CD-CG1 4.02Å; K167-V289 HydrophobicContact CG-CG1 4.43Å; K167-E291 IonicContact NZ-OE1 2.67Å; K167-E291 PolarHBondContact NZ-OE1 3.48Å; K167-E291 IonicContact NZ-OE2 3.26Å; K167-E291 PolarHBondContact NZ-OE2 3.4Å
168L98.8Very high97.8Very high0 Ų027 Ų270%015%0.154CC..EExtended strand (participates in β ladder)trans-103.5124.2161.2168.364.1000108.2I139 M141 H159 L162 I170 I290I139-L168 HydrophobicContact CB-CD1 3.73Å; I139-L168 HydrophobicContact CG2-CD1 3.59Å; I139-L168 CarbonylContact O-C 3.51Å; I139-L168 WeakPolarHBondContact O-CA 3.36Å; M141-L168 HydrophobicContact CE-CD1 4.02Å; M141-L168 HydrophobicContact CG-CD1 4.35Å; M141-L168 HydrophobicContact SD-CD1 4.33Å; H159-L168 HydrophobicContact CB-CD2 4.44Å; L162-L168 HydrophobicContact CD1-CB 3.87Å; L162-L168 HydrophobicContact CD2-CB 4.14Å; L162-L168 HydrophobicContact CG-CB 4.47Å; L168-I170 HydrophobicContact CG-CG1 4.36Å; L168-I290 HydrophobicContact CB-CB 4.18Å; L168-I290 HydrophobicContact CD2-CD1 3.71Å; L168-I290 HydrophobicContact CG-CD1 4Å; L168-I290 PolarHBondContact N-O 2.97Å; L168-I290 VanDerWaalsContact N-O 3.07Å; L168-I290 PolarHBondContact O-N 3.4Å
169L98.9Very high97.8Very high0 Ų027.2 Ų27.20%016%0.155CC..EExtended strand (participates in β ladder)trans-112130.1179.1-179.6148000110.1F35 L40 F138 I139 H140 M141 I171 V287 I288 V289F35-L169 HydrophobicContact CE1-CD1 3.86Å; F35-L169 HydrophobicContact CZ-CD1 4.22Å; L40-L169 HydrophobicContact CD1-CD1 3.94Å; F138-L169 HydrophobicContact CE2-CB 3.71Å; F138-L169 HydrophobicContact CE2-CD1 4.37Å; F138-L169 HydrophobicContact CZ-CB 3.88Å; F138-L169 HydrophobicContact CZ-CD1 4.11Å; F138-L169 HydrophobicContact CZ-CG 4.49Å; I139-L169 PolarHBondContact O-N 2.68Å; H140-L169 CarbonylContact C-O 3.57Å; H140-L169 WeakPolarHBondContact CA-O 3.41Å; H140-L169 HydrophobicContact CB-CB 4.25Å; H140-L169 HydrophobicContact CB-CD2 4.12Å; M141-L169 PolarHBondContact N-O 2.96Å; L169-I171 HydrophobicContact CD2-CD1 3.94Å; L169-I171 HydrophobicContact CD2-CG1 3.54Å; L169-V287 HydrophobicContact CD1-CG1 3.75Å; L169-V287 HydrophobicContact CD2-CG1 4.24Å; L169-V287 HydrophobicContact CG-CG1 3.76Å; L169-I288 CarbonylContact C-O 3.43Å; L169-I288 WeakPolarHBondContact CA-O 3.33Å; L169-V289 HydrophobicContact CD1-CG2 4.38Å
170I98.8Very high97.7Very high0 Ų027.2 Ų27.20%016%0.155CC..EExtended strand (participates in β ladder)trans-122.2131.7176.5-55.8175.7000107.8M141 L145 I155 L168 L172 I204 V287 I288 I290M141-I170 HydrophobicContact CB-CG1 4.32Å; M141-I170 WeakPolarHBondContact O-CA 3.38Å; M141-I170 HydrophobicContact SD-CD1 4.47Å; M141-I170 HydrophobicContact SD-CG1 4.31Å; L145-I170 HydrophobicContact CD1-CD1 4.14Å; L145-I170 HydrophobicContact CD1-CG2 3.51Å; L145-I170 HydrophobicContact CG-CG2 4.43Å; I155-I170 HydrophobicContact CD1-CD1 4.05Å; I155-I170 HydrophobicContact CG1-CD1 4.13Å; L168-I170 HydrophobicContact CG-CG1 4.36Å; I170-L172 HydrophobicContact CG2-CD2 3.98Å; I170-I204 HydrophobicContact CD1-CG2 4.22Å; I170-V287 CarbonylContact O-C 3.53Å; I170-V287 WeakPolarHBondContact O-CA 3.49Å; I170-I288 HydrophobicContact CB-CB 4.42Å; I170-I288 PolarHBondContact N-O 3.15Å; I170-I288 PolarHBondContact O-N 2.91Å; I170-I290 HydrophobicContact CD1-CD1 3.64Å; I170-I290 HydrophobicContact CG1-CD1 4.29Å
171I98.6Very high97.7Very high3 Ų322.5 Ų22.52%0.01514%0.142CC..EExtended strand (participates in β ladder)trans-117.8128.7170.6-48.7-169.1000108.7M32 M141 V142 Q143 L169 L285 S286 V287M32-I171 HydrophobicContact CE-CG2 4.12Å; M32-I171 HydrophobicContact CG-CD1 4.38Å; M32-I171 HydrophobicContact SD-CD1 4.48Å; M141-I171 PolarHBondContact O-N 3.32Å; V142-I171 HydrophobicContact CG1-CB 4.19Å; V142-I171 HydrophobicContact CG1-CD1 4.28Å; V142-I171 HydrophobicContact CG2-CB 4.49Å; V142-I171 HydrophobicContact CG2-CD1 4.05Å; V142-I171 HydrophobicContact CG2-CG1 4.11Å; Q143-I171 PolarHBondContact N-O 3.43Å; L169-I171 HydrophobicContact CD2-CD1 3.94Å; L169-I171 HydrophobicContact CD2-CG1 3.54Å; I171-L285 HydrophobicContact CG2-CB 4.45Å; I171-L285 HydrophobicContact CG2-CD1 4.23Å; I171-S286 WeakPolarHBondContact CA-O 3.49Å; I171-V287 HydrophobicContact CD1-CG2 3.97Å; I171-V287 HydrophobicContact CG1-CG1 4.4Å; I171-V287 HydrophobicContact CG1-CG2 3.94Å; I171-V287 HydrophobicContact CG2-CG2 4.44Å
172L97.7Very high97.6Very high2 Ų221.5 Ų21.51%0.0114%0.137CC..EExtended strand (participates in β ladder)trans-151.9174.3175.671.1168.3000111.2Y146 I170 T200 I204 L285 S286 I288Y146-L172 WeakPolarHBondContact OH-CA 3.27Å; Y146-L172 WeakPolarHBondContact OH-CB 3.28Å; I170-L172 HydrophobicContact CG2-CD2 3.98Å; L172-T200 WeakPolarHBondContact CD1-O 3.43Å; L172-I204 HydrophobicContact CD1-CB 4.48Å; L172-I204 HydrophobicContact CD1-CD1 4.39Å; L172-I204 HydrophobicContact CD1-CG1 3.43Å; L172-I204 VanDerWaalsContact CD1-CG1 3.43Å; L172-I204 HydrophobicContact CD2-CG1 4.32Å; L172-L285 CarbonylContact O-C 3.51Å; L172-L285 WeakPolarHBondContact O-CA 3.37Å; L172-S286 PolarHBondContact N-O 3.34Å; L172-S286 PolarHBondContact O-N 3.5Å; L172-I288 HydrophobicContact CD2-CD1 3.86Å; L172-I288 HydrophobicContact CD2-CG1 4.45Å
173V98.3Very high97.5Very high6 Ų622.1 Ų22.14%0.03614%0.138CC..EExtended strand (participates in β ladder)trans-63.7143.6173.1-62.50000111.2Y146 W179 W183 T200 S201 L285Y146-V173 HydrophobicContact CE1-CG2 4.27Å; Y146-V173 PolarHBondContact OH-N 3.35Å; V173-W179 HydrophobicContact CB-CB 4.36Å; V173-W179 HydrophobicContact CB-CG 4.2Å; V173-W179 HydrophobicContact CG1-CG 3.99Å; V173-W179 HydrophobicContact CG2-CB 4.11Å; V173-W179 HydrophobicContact CG2-CG 4.33Å; V173-W183 HydrophobicContact CG2-CH2 3.51Å; V173-W183 HydrophobicContact CG2-CZ3 3.53Å; V173-T200 HydrophobicContact CG2-CG2 4.02Å; V173-T200 WeakPolarHBondContact O-CA 3.48Å; V173-S201 PolarHBondContact O-N 2.91Å; V173-L285 HydrophobicContact CG1-CD2 4.01Å
174S98.5Very high97.4Very high1 Ų126.2 Ų26.21%0.00716%0.155CC..  trans-71.8145.9-176.9175.60000112A176 S177 S201 E219 N284 S286S174-A176 PolarHBondContact O-N 3.5Å; S174-A176 VanDerWaalsContact O-N 3.16Å; S174-A176 PolarHBondContact OG-N 3.14Å; S174-S177 WeakPolarHBondContact O-CB 3.19Å; S174-S177 PolarHBondContact O-N 3.46Å; S174-S177 PolarHBondContact O-OG 3.42Å; S174-S201 WeakPolarHBondContact CA-OG 3.08Å; S174-E219 VanDerWaalsContact CB-OE2 3.23Å; S174-E219 WeakPolarHBondContact CB-OE2 3.18Å; S174-E219 VanDerWaalsContact OG-CD 3.3Å; S174-E219 PolarHBondContact OG-OE1 3.24Å; S174-E219 PolarHBondContact OG-OE2 3.16Å; S174-N284 VanDerWaalsContact CB-O 3.31Å; S174-N284 WeakPolarHBondContact CB-O 3.3Å; S174-N284 PolarHBondContact N-O 2.86Å; S174-S286 VanDerWaalsContact CA-OG 3.32Å; S174-S286 WeakPolarHBondContact CA-OG 3.48Å; S174-S286 WeakPolarHBondContact CB-OG 3.26Å; S174-S286 PolarHBondContact OG-OG 2.94Å
175G97.4Very high97.5Very high24 Ų2426.4 Ų26.425%0.24714%0.14CC..THydrogen-bonded Turntrans-64.4-8.816700000113.8E180 T200 S201G175-E180 WeakPolarHBondContact O-CG 3.34Å; G175-T200 WeakPolarHBondContact CA-OG1 2.83Å; G175-S201 PolarHBondContact N-OG 2.98Å
176A96.2Very high97.5Very high68 Ų6822.9 Ų22.956%0.56212%0.123SC*.THydrogen-bonded Turntrans-106.113.4171.300000113S174 N282S174-A176 PolarHBondContact O-N 3.5Å; S174-A176 VanDerWaalsContact O-N 3.16Å; S174-A176 PolarHBondContact OG-N 3.14Å; A176-N282 PolarHBondContact O-ND2 3.17Å
177S98.1Very high97.2Very high2 Ų223.4 Ų23.41%0.01413%0.128CC..SBendtrans-83.8167177.970.50000112.5S174 W179 E180 N284S174-S177 WeakPolarHBondContact O-CB 3.19Å; S174-S177 PolarHBondContact O-N 3.46Å; S174-S177 PolarHBondContact O-OG 3.42Å; S177-W179 PolarHBondContact O-N 2.93Å; S177-W179 WeakPolarHBondContact OG-CB 3.21Å; S177-W179 PolarHBondContact OG-N 3.02Å; S177-E180 PolarHBondContact O-N 3.2Å; S177-N284 WeakPolarHBondContact CB-O 3.34Å
178G98.1Very high96.9Very high0 Ų027.4 Ų27.40%016%0.159CC..Hα-helixtrans-64.1-24170.600000112.5T181 L182 N282G178-T181 PolarHBondContact O-N 3.09Å; G178-L182 WeakPolarHBondContact O-CB 3.47Å; G178-L182 PolarHBondContact O-N 3.04Å; G178-N282 PolarHBondContact N-O 2.58Å
179W97.9Very high96.7Very high6 Ų632.3 Ų32.32%0.02318%0.181CC..Hα-helixtrans-61.3-45.2176.1-63.1107.8000111.6V173 S177 T181 L182 W183 M224 F243 L244 F281 N283V173-W179 HydrophobicContact CB-CB 4.36Å; V173-W179 HydrophobicContact CB-CG 4.2Å; V173-W179 HydrophobicContact CG1-CG 3.99Å; V173-W179 HydrophobicContact CG2-CB 4.11Å; V173-W179 HydrophobicContact CG2-CG 4.33Å; S177-W179 PolarHBondContact O-N 2.93Å; S177-W179 WeakPolarHBondContact OG-CB 3.21Å; S177-W179 PolarHBondContact OG-N 3.02Å; W179-T181 VanDerWaalsContact C-N 3.31Å; W179-T181 PolarHBondContact O-N 2.92Å; W179-L182 PolarHBondContact O-N 2.85Å; W179-W183 HydrophobicContact CB-CD2 4.15Å; W179-W183 HydrophobicContact CB-CE3 4.11Å; W179-W183 HydrophobicContact CB-CH2 3.98Å; W179-W183 HydrophobicContact CB-CZ2 3.99Å; W179-W183 HydrophobicContact CB-CZ3 4.02Å; W179-W183 AromaticContact CD2-CZ2 3.97Å; W179-W183 HydrophobicContact CD2-CZ2 3.97Å; W179-W183 AromaticContact CE3-CE2 3.66Å; W179-W183 HydrophobicContact CE3-CH2 4.46Å; W179-W183 AromaticContact CE3-CZ2 3.52Å; W179-W183 HydrophobicContact CE3-CZ2 3.52Å; W179-W183 AromaticContact CE3-NE1 3.62Å; W179-W183 HydrophobicContact CG-CH2 4.37Å; W179-W183 HydrophobicContact CG-CZ2 4.22Å; W179-W183 HydrophobicContact CZ3-CZ2 4.22Å; W179-W183 VanDerWaalsContact O-CB 3.3Å; W179-W183 WeakPolarHBondContact O-CB 3.37Å; W179-W183 PolarHBondContact O-N 3.42Å; W179-M224 HydrophobicContact CZ2-SD 4.49Å; W179-F243 AromaticContact CH2-CD1 3.77Å; W179-F243 HydrophobicContact CH2-CD1 3.77Å; W179-F243 AromaticContact CH2-CE1 3.76Å; W179-F243 HydrophobicContact CH2-CE1 3.76Å; W179-F243 HydrophobicContact CZ2-CD1 4.29Å; W179-F243 AromaticContact CZ2-CE1 3.95Å; W179-F243 HydrophobicContact CZ2-CE1 3.95Å; W179-L244 HydrophobicContact CH2-CD2 3.89Å; W179-L244 HydrophobicContact CZ2-CD2 4.39Å; W179-L244 HydrophobicContact CZ3-CD2 4.1Å; W179-F281 AromaticContact CD1-CE1 3.83Å; W179-F281 AromaticContact CD2-CE1 3.69Å; W179-F281 HydrophobicContact CD2-CE1 3.69Å; W179-F281 HydrophobicContact CD2-CZ 4.03Å; W179-F281 AromaticContact CE2-CE1 3.57Å; W179-F281 HydrophobicContact CE3-CE1 4.3Å; W179-F281 HydrophobicContact CE3-CZ 4.32Å; W179-F281 AromaticContact CG-CE1 3.89Å; W179-F281 HydrophobicContact CG-CE1 3.89Å; W179-F281 HydrophobicContact CG-CZ 4.18Å; W179-F281 HydrophobicContact CZ2-CE1 4.09Å; W179-F281 AromaticContact NE1-CE1 3.65Å; W179-N283 PolarHBondContact NE1-OD1 3.34Å
180E97Very high96.3Very high22 Ų2232.9 Ų32.910%0.10318%0.184CC..Hα-helixtrans-55.1-48.2176.917972.1167.400111.3G175 S177 K184 T200G175-E180 WeakPolarHBondContact O-CG 3.34Å; S177-E180 PolarHBondContact O-N 3.2Å; E180-K184 HydrophobicContact CG-CD 4.09Å; E180-K184 VanDerWaalsContact O-CB 3.26Å; E180-K184 WeakPolarHBondContact O-CB 3.35Å; E180-K184 WeakPolarHBondContact O-CG 3.47Å; E180-K184 PolarHBondContact O-N 3.33Å; E180-K184 WeakPolarHBondContact OE1-CE 3.4Å; E180-K184 IonicContact OE1-NZ 2.58Å; E180-K184 PolarHBondContact OE1-NZ 3.31Å; E180-T200 HydrophobicContact CB-CG2 4.12Å; E180-T200 WeakPolarHBondContact OE2-CG2 3.1Å; E180-T200 PolarHBondContact OE2-OG1 3.01Å
181T96.6Very high95.8Very high40 Ų4034.2 Ų34.225%0.24519%0.193CC..Hα-helixtrans-62.4-49.4178.9-59.30000111.3G178 W179 K185 E270G178-T181 PolarHBondContact O-N 3.09Å; W179-T181 VanDerWaalsContact C-N 3.31Å; W179-T181 PolarHBondContact O-N 2.92Å; T181-K185 WeakPolarHBondContact O-CB 3.39Å; T181-K185 PolarHBondContact O-N 2.61Å; T181-E270 HydrophobicContact CG2-CB 3.87Å; T181-E270 PolarHBondContact OG1-O 3.36Å; T181-E270 VanDerWaalsContact OG1-O 3.12Å
182L96.8Very high94.8Very high0 Ų037.5 Ų37.50%021%0.211CC..Hα-helixtrans-61-48.3-178.4-176.467.9000111.2G178 W179 K185 Y186 L244 I262 L266G178-L182 WeakPolarHBondContact O-CB 3.47Å; G178-L182 PolarHBondContact O-N 3.04Å; W179-L182 PolarHBondContact O-N 2.85Å; L182-K185 PolarHBondContact O-N 3.04Å; L182-Y186 HydrophobicContact CD1-CD2 3.9Å; L182-Y186 PolarHBondContact O-N 3.15Å; L182-L244 HydrophobicContact CD2-CB 4.32Å; L182-L244 WeakPolarHBondContact CD2-O 3.24Å; L182-I262 HydrophobicContact CD1-CG2 4.27Å; L182-L266 HydrophobicContact CD1-CD2 4.34Å; L182-L266 HydrophobicContact CD2-CD2 4.44Å
183W95.9Very high93.8Very high23 Ų2339.3 Ų39.39%0.08722%0.22CC..Hα-helixtrans-70.3-42.5-177.1-64-21.1000112.8Y146 V173 W179 K185 G187 Y198 I199 T200Y146-W183 HydrophobicContact CE1-CH2 4.13Å; V173-W183 HydrophobicContact CG2-CH2 3.51Å; V173-W183 HydrophobicContact CG2-CZ3 3.53Å; W179-W183 HydrophobicContact CB-CD2 4.15Å; W179-W183 HydrophobicContact CB-CE3 4.11Å; W179-W183 HydrophobicContact CB-CH2 3.98Å; W179-W183 HydrophobicContact CB-CZ2 3.99Å; W179-W183 HydrophobicContact CB-CZ3 4.02Å; W179-W183 AromaticContact CD2-CZ2 3.97Å; W179-W183 HydrophobicContact CD2-CZ2 3.97Å; W179-W183 AromaticContact CE3-CE2 3.66Å; W179-W183 HydrophobicContact CE3-CH2 4.46Å; W179-W183 AromaticContact CE3-CZ2 3.52Å; W179-W183 HydrophobicContact CE3-CZ2 3.52Å; W179-W183 AromaticContact CE3-NE1 3.62Å; W179-W183 HydrophobicContact CG-CH2 4.37Å; W179-W183 HydrophobicContact CG-CZ2 4.22Å; W179-W183 HydrophobicContact CZ3-CZ2 4.22Å; W179-W183 VanDerWaalsContact O-CB 3.3Å; W179-W183 WeakPolarHBondContact O-CB 3.37Å; W179-W183 PolarHBondContact O-N 3.42Å; W183-K185 PolarHBondContact O-N 2.78Å; W183-G187 VanDerWaalsContact O-CA 3.24Å; W183-G187 WeakPolarHBondContact O-CA 3.46Å; W183-G187 PolarHBondContact O-N 3.45Å; W183-Y198 HydrophobicContact CB-CD2 3.78Å; W183-Y198 HydrophobicContact CB-CG 3.87Å; W183-Y198 AromaticContact CD1-CD1 3.7Å; W183-Y198 AromaticContact CD1-CD2 3.78Å; W183-Y198 AromaticContact CD1-CE1 3.81Å; W183-Y198 AromaticContact CD1-CE2 3.89Å; W183-Y198 AromaticContact CD1-CG 3.69Å; W183-Y198 AromaticContact CD1-CZ 3.91Å; W183-Y198 AromaticContact CD2-CD1 3.7Å; W183-Y198 HydrophobicContact CD2-CD1 3.7Å; W183-Y198 HydrophobicContact CD2-CD2 4.37Å; W183-Y198 HydrophobicContact CD2-CE1 4.49Å; W183-Y198 AromaticContact CD2-CG 3.63Å; W183-Y198 HydrophobicContact CD2-CG 3.63Å; W183-Y198 AromaticContact CE2-CD1 3.48Å; W183-Y198 VanDerWaalsContact CE2-CD1 3.48Å; W183-Y198 AromaticContact CE2-CE1 3.98Å; W183-Y198 AromaticContact CE2-CG 3.94Å; W183-Y198 HydrophobicContact CE3-CD1 4.38Å; W183-Y198 HydrophobicContact CE3-CG 4.21Å; W183-Y198 AromaticContact CG-CD1 3.82Å; W183-Y198 HydrophobicContact CG-CD1 3.82Å; W183-Y198 AromaticContact CG-CD2 3.71Å; W183-Y198 HydrophobicContact CG-CD2 3.71Å; W183-Y198 HydrophobicContact CG-CE1 4.38Å; W183-Y198 HydrophobicContact CG-CE2 4.28Å; W183-Y198 AromaticContact CG-CG 3.46Å; W183-Y198 HydrophobicContact CG-CG 3.46Å; W183-Y198 VanDerWaalsContact CG-CG 3.46Å; W183-Y198 AromaticContact CZ2-CD1 4Å; W183-Y198 HydrophobicContact CZ2-CD1 4Å; W183-Y198 AromaticContact NE1-CD1 3.49Å; W183-Y198 AromaticContact NE1-CE1 3.55Å; W183-Y198 AromaticContact NE1-CG 3.97Å; W183-I199 VanDerWaalsContact CZ3-O 3.32Å; W183-I199 WeakPolarHBondContact CZ3-O 3.42Å; W183-T200 HydrophobicContact CE3-CG2 3.97Å; W183-T200 HydrophobicContact CZ3-CG2 3.81Å
184K95.1Very high92.7Very high161 Ų16144.9 Ų44.970%0.725%0.25SC*.Hα-helixtrans-59.8-37.6175.4-82.7-179.6163164.60112.4E180E180-K184 HydrophobicContact CG-CD 4.09Å; E180-K184 VanDerWaalsContact O-CB 3.26Å; E180-K184 WeakPolarHBondContact O-CB 3.35Å; E180-K184 WeakPolarHBondContact O-CG 3.47Å; E180-K184 PolarHBondContact O-N 3.33Å; E180-K184 WeakPolarHBondContact OE1-CE 3.4Å; E180-K184 IonicContact OE1-NZ 2.58Å; E180-K184 PolarHBondContact OE1-NZ 3.31Å
185K96.4Very high91.7Very high91 Ų9149.5 Ų49.540%0.39627%0.274SS..Hα-helixtrans-85.3-43.7-174.9-169.9168.9-176.6174.80113.3T181 L182 W183 E265T181-K185 WeakPolarHBondContact O-CB 3.39Å; T181-K185 PolarHBondContact O-N 2.61Å; L182-K185 PolarHBondContact O-N 3.04Å; W183-K185 PolarHBondContact O-N 2.78Å; K185-E265 HydrophobicContact CD-CG 4.42Å; K185-E265 WeakPolarHBondContact CD-OE1 3.34Å; K185-E265 IonicContact NZ-OE1 2.88Å; K185-E265 PolarHBondContact NZ-OE1 2.96Å; K185-E265 IonicContact NZ-OE2 2.68Å; K185-E265 PolarHBondContact NZ-OE2 3.36Å
186Y95.8Very high91.1Very high10 Ų1048.6 Ų48.64%0.03926%0.264CS..Hα-helixtrans-115.2-6.2-170.5-59.7-75.2000114L182 S188 H189 L190 L258 Q261 I262 E265L182-Y186 HydrophobicContact CD1-CD2 3.9Å; L182-Y186 PolarHBondContact O-N 3.15Å; Y186-S188 VanDerWaalsContact C-N 3.27Å; Y186-S188 PolarHBondContact O-N 3.48Å; Y186-H189 WeakPolarHBondContact O-CA 3.39Å; Y186-H189 WeakPolarHBondContact O-CB 3.39Å; Y186-H189 PolarHBondContact O-N 3.09Å; Y186-L190 PolarHBondContact O-N 2.68Å; Y186-L258 HydrophobicContact CD1-CD1 3.93Å; Y186-Q261 HydrophobicContact CE1-CB 3.85Å; Y186-Q261 PolarHBondContact OH-O 2.65Å; Y186-Q261 VanDerWaalsContact OH-O 3.12Å; Y186-I262 HydrophobicContact CD1-CD1 4.3Å; Y186-I262 HydrophobicContact CD1-CG1 3.75Å; Y186-I262 HydrophobicContact CD2-CG1 3.91Å; Y186-I262 HydrophobicContact CE1-CG1 4.06Å; Y186-I262 HydrophobicContact CE2-CG1 4.16Å; Y186-I262 HydrophobicContact CG-CD1 4.12Å; Y186-I262 HydrophobicContact CG-CG1 3.67Å; Y186-E265 HydrophobicContact CE2-CB 3.66Å; Y186-E265 HydrophobicContact CE2-CG 3.76Å; Y186-E265 PolarHBondContact OH-OE2 3.05Å
187G92.5Very high90.7Very high10 Ų1047.9 Ų47.910%0.10325%0.248CC..G310 helixtrans-58.9-36.4-172.600000114.2W183 H189 L190W183-G187 VanDerWaalsContact O-CA 3.24Å; W183-G187 WeakPolarHBondContact O-CA 3.46Å; W183-G187 PolarHBondContact O-N 3.45Å; G187-H189 PolarHBondContact O-N 3.4Å; G187-L190 PolarHBondContact O-N 3.46Å
188S92.8Very high90.4Very high107 Ų10749.7 Ų49.775%0.74826%0.255SS*.G310 helixtrans-69.6-14.5174.957.60000114.7Y186Y186-S188 VanDerWaalsContact C-N 3.27Å; Y186-S188 PolarHBondContact O-N 3.48Å
189H93Very high90.3Very high102 Ų10250.4 Ų50.447%0.47226%0.259SS..G310 helixtrans-98.1-8.4178.1-56.290.4000112.5M5 Y186 G187 L258M5-H189 WeakPolarHBondContact CE-O 3.45Å; Y186-H189 WeakPolarHBondContact O-CA 3.39Å; Y186-H189 WeakPolarHBondContact O-CB 3.39Å; Y186-H189 PolarHBondContact O-N 3.09Å; G187-H189 PolarHBondContact O-N 3.4Å; H189-L258 HydrophobicContact CB-CD1 3.85Å; H189-L258 HydrophobicContact CB-CD2 4.15Å
190L92.1Very high90.3Very high12 Ų1250.1 Ų50.16%0.06326%0.257CS..SBendtrans-97.6153.3179.2-66.2172.7000110Y186 G187 L192 T245 F250 I262Y186-L190 PolarHBondContact O-N 2.68Å; G187-L190 PolarHBondContact O-N 3.46Å; L190-L192 PolarHBondContact O-N 3.15Å; L190-T245 HydrophobicContact CD2-CG2 4.4Å; L190-F250 HydrophobicContact CD2-CD2 4.42Å; L190-F250 HydrophobicContact CD2-CE2 4.06Å; L190-I262 HydrophobicContact CD2-CD1 4.11Å
191P87.8Confident90.4Very high29 Ų2949.2 Ų49.219%0.18825%0.254CS..  trans-76.356.2-177.736.8-39.8000111.6M5 K6 S7 T247M5-P191 HydrophobicContact CB-CB 4.18Å; M5-P191 HydrophobicContact CB-CG 3.89Å; K6-P191 VanDerWaalsContact C-CG 3.46Å; S7-P191 VanDerWaalsContact CB-O 3.27Å; S7-P191 WeakPolarHBondContact CB-O 3.35Å; P191-T247 WeakPolarHBondContact CD-OG1 3.31Å; P191-T247 HydrophobicContact CG-CG2 3.97Å; P191-T247 WeakPolarHBondContact CG-OG1 3.49Å
192L77.9Confident90.4Very high72 Ų7249.3 Ų49.338%0.37726%0.258SS..  trans-59.7138.3172.1-152.394.3000109.2L190 C196 Y198L190-L192 PolarHBondContact O-N 3.15Å; L192-C196 WeakPolarHBondContact CD2-O 3.43Å; L192-C196 VanDerWaalsContact CG-O 3.26Å; L192-C196 WeakPolarHBondContact CG-O 3.38Å; L192-Y198 HydrophobicContact CD1-CD1 3.69Å; L192-Y198 HydrophobicContact CD1-CD2 3.57Å; L192-Y198 HydrophobicContact CD1-CE1 3.38Å; L192-Y198 HydrophobicContact CD1-CE2 3.25Å; L192-Y198 HydrophobicContact CD1-CG 3.77Å
193N75.1Confident90.5Very high40 Ų4052.5 Ų52.521%0.21428%0.275CS..  trans-126.3175.1174.864.716.2000110S7 T10 L195 C196S7-N193 VanDerWaalsContact CB-ND2 3.28Å; S7-N193 WeakPolarHBondContact CB-ND2 3.32Å; S7-N193 PolarHBondContact OG-ND2 2.99Å; T10-N193 WeakPolarHBondContact CG2-ND2 3.24Å; N193-L195 PolarHBondContact O-N 2.88Å; N193-L195 WeakPolarHBondContact OD1-CA 3.47Å; N193-L195 VanDerWaalsContact OD1-CB 3.22Å; N193-L195 WeakPolarHBondContact OD1-CB 3.38Å; N193-L195 PolarHBondContact OD1-N 2.65Å; N193-C196 PolarHBondContact O-N 3.21Å; N193-C196 PolarHBondContact OD1-N 3.17Å
194D76.4Confident90.6Very high123 Ų12351.4 Ų51.466%0.65827%0.271SS*.THydrogen-bonded Turntrans-66.65.2179.5-64.7-6.7000114.2
195L77.7Confident90.8Very high98 Ų9846.2 Ų46.251%0.51325%0.249SC..THydrogen-bonded Turntrans-101.1-15.5-179.4-53.1173.8000113.1I9 N193I9-L195 HydrophobicContact CG2-CB 3.82Å; I9-L195 HydrophobicContact CG2-CD1 3.93Å; N193-L195 PolarHBondContact O-N 2.88Å; N193-L195 WeakPolarHBondContact OD1-CA 3.47Å; N193-L195 VanDerWaalsContact OD1-CB 3.22Å; N193-L195 WeakPolarHBondContact OD1-CB 3.38Å; N193-L195 PolarHBondContact OD1-N 2.65Å
196C83.6Confident90.8Very high5 Ų544.5 Ų44.53%0.03425%0.252CS..  trans-145.3129.3-178.8-171.60000111Y146 L192 N193Y146-C196 CarbonylContact O-C 3.54Å; Y146-C196 VanDerWaalsContact O-CA 3.29Å; Y146-C196 WeakPolarHBondContact O-CA 3.28Å; L192-C196 WeakPolarHBondContact CD2-O 3.43Å; L192-C196 VanDerWaalsContact CG-O 3.26Å; L192-C196 WeakPolarHBondContact CG-O 3.38Å; N193-C196 PolarHBondContact O-N 3.21Å; N193-C196 PolarHBondContact OD1-N 3.17Å
197F88.6Confident91Very high53 Ų5346 Ų4623%0.23226%0.26CS..  trans-116.4135.4-179.4-60.9-84.8000111.1Y146 V148 I199Y146-F197 WeakPolarHBondContact O-CD2 3.37Å; Y146-F197 PolarHBondContact O-N 3.22Å; V148-F197 WeakPolarHBondContact O-CD2 3.39Å; V148-F197 WeakPolarHBondContact O-CE2 3.44Å; F197-I199 HydrophobicContact CB-CG2 4.14Å; F197-I199 PolarHBondContact O-N 3.04Å
198Y92.6Very high91.2Very high40 Ų4045.5 Ų45.516%0.15726%0.255CS..  trans-7999.3170.6-62.9-26.3000109.3W183 L192 E246W183-Y198 HydrophobicContact CB-CD2 3.78Å; W183-Y198 HydrophobicContact CB-CG 3.87Å; W183-Y198 AromaticContact CD1-CD1 3.7Å; W183-Y198 AromaticContact CD1-CD2 3.78Å; W183-Y198 AromaticContact CD1-CE1 3.81Å; W183-Y198 AromaticContact CD1-CE2 3.89Å; W183-Y198 AromaticContact CD1-CG 3.69Å; W183-Y198 AromaticContact CD1-CZ 3.91Å; W183-Y198 AromaticContact CD2-CD1 3.7Å; W183-Y198 HydrophobicContact CD2-CD1 3.7Å; W183-Y198 HydrophobicContact CD2-CD2 4.37Å; W183-Y198 HydrophobicContact CD2-CE1 4.49Å; W183-Y198 AromaticContact CD2-CG 3.63Å; W183-Y198 HydrophobicContact CD2-CG 3.63Å; W183-Y198 AromaticContact CE2-CD1 3.48Å; W183-Y198 VanDerWaalsContact CE2-CD1 3.48Å; W183-Y198 AromaticContact CE2-CE1 3.98Å; W183-Y198 AromaticContact CE2-CG 3.94Å; W183-Y198 HydrophobicContact CE3-CD1 4.38Å; W183-Y198 HydrophobicContact CE3-CG 4.21Å; W183-Y198 AromaticContact CG-CD1 3.82Å; W183-Y198 HydrophobicContact CG-CD1 3.82Å; W183-Y198 AromaticContact CG-CD2 3.71Å; W183-Y198 HydrophobicContact CG-CD2 3.71Å; W183-Y198 HydrophobicContact CG-CE1 4.38Å; W183-Y198 HydrophobicContact CG-CE2 4.28Å; W183-Y198 AromaticContact CG-CG 3.46Å; W183-Y198 HydrophobicContact CG-CG 3.46Å; W183-Y198 VanDerWaalsContact CG-CG 3.46Å; W183-Y198 AromaticContact CZ2-CD1 4Å; W183-Y198 HydrophobicContact CZ2-CD1 4Å; W183-Y198 AromaticContact NE1-CD1 3.49Å; W183-Y198 AromaticContact NE1-CE1 3.55Å; W183-Y198 AromaticContact NE1-CG 3.97Å; L192-Y198 HydrophobicContact CD1-CD1 3.69Å; L192-Y198 HydrophobicContact CD1-CD2 3.57Å; L192-Y198 HydrophobicContact CD1-CE1 3.38Å; L192-Y198 HydrophobicContact CD1-CE2 3.25Å; L192-Y198 HydrophobicContact CD1-CG 3.77Å; Y198-E246 HydrophobicContact CE1-CB 4.3Å; Y198-E246 HydrophobicContact CE1-CG 3.9Å
199I95.2Very high91.5Very high15 Ų1545.3 Ų45.38%0.07725%0.246CC..  trans-130.3143.1178.661.2172.8000109.9L145 Y146 I151 W183 F197 D203 I204L145-I199 HydrophobicContact CB-CD1 3.61Å; Y146-I199 HydrophobicContact CD1-CD1 4.33Å; Y146-I199 HydrophobicContact CD1-CG1 3.69Å; Y146-I199 HydrophobicContact CE1-CG1 3.98Å; Y146-I199 WeakPolarHBondContact CE1-O 3.41Å; I151-I199 HydrophobicContact CD1-CD1 3.51Å; I151-I199 HydrophobicContact CD1-CG1 4.44Å; I151-I199 HydrophobicContact CD1-CG2 3.66Å; I151-I199 HydrophobicContact CG1-CD1 4.28Å; W183-I199 VanDerWaalsContact CZ3-O 3.32Å; W183-I199 WeakPolarHBondContact CZ3-O 3.42Å; F197-I199 HydrophobicContact CB-CG2 4.14Å; F197-I199 PolarHBondContact O-N 3.04Å; I199-D203 WeakPolarHBondContact CA-OD2 3.36Å; I199-I204 HydrophobicContact CD1-CD1 4.28Å
200T98.2Very high91.7Very high0 Ų045.7 Ų45.70%026%0.26CS..  trans-121.8174.5174.968.80000111.2L172 V173 G175 E180 W183 A202 D203 I204L172-T200 WeakPolarHBondContact CD1-O 3.43Å; V173-T200 HydrophobicContact CG2-CG2 4.02Å; V173-T200 WeakPolarHBondContact O-CA 3.48Å; G175-T200 WeakPolarHBondContact CA-OG1 2.83Å; E180-T200 HydrophobicContact CB-CG2 4.12Å; E180-T200 WeakPolarHBondContact OE2-CG2 3.1Å; E180-T200 PolarHBondContact OE2-OG1 3.01Å; W183-T200 HydrophobicContact CE3-CG2 3.97Å; W183-T200 HydrophobicContact CZ3-CG2 3.81Å; T200-A202 PolarHBondContact O-N 3.46Å; T200-A202 PolarHBondContact OG1-N 3.34Å; T200-D203 PolarHBondContact N-OD2 2.98Å; T200-D203 WeakPolarHBondContact O-CB 3.4Å; T200-D203 PolarHBondContact O-N 3.26Å; T200-I204 PolarHBondContact O-N 3.14Å
201S98.3Very high91.9Very high3 Ų347.7 Ų47.72%0.02128%0.278CS..Hα-helixtrans-56.2-29.9175.861.60000113.2V173 S174 G175 D203 I204 E205 S286V173-S201 PolarHBondContact O-N 2.91Å; S174-S201 WeakPolarHBondContact CA-OG 3.08Å; G175-S201 PolarHBondContact N-OG 2.98Å; S201-D203 PolarHBondContact O-N 3.05Å; S201-I204 PolarHBondContact O-N 2.57Å; S201-E205 WeakPolarHBondContact O-CB 3.4Å; S201-E205 WeakPolarHBondContact O-CG 3.4Å; S201-E205 PolarHBondContact O-N 2.92Å; S201-S286 VanDerWaalsContact CB-CB 3.44Å; S201-S286 VanDerWaalsContact CB-OG 3.23Å; S201-S286 WeakPolarHBondContact CB-OG 3.43Å; S201-S286 PolarHBondContact OG-OG 2.99Å
202A97.9Very high92.3Very high41 Ų4149.5 Ų49.534%0.33930%0.302SS..Hα-helixtrans-62.9-39.8175.200000112.5T200 A206T200-A202 PolarHBondContact O-N 3.46Å; T200-A202 PolarHBondContact OG1-N 3.34Å; A202-A206 WeakPolarHBondContact O-CB 3.33Å; A202-A206 PolarHBondContact O-N 2.83Å
203D98Very high93.3Very high67 Ų6747.5 Ų47.536%0.35829%0.292SS..Hα-helixtrans-66.9-41.6176.2-59.9-58.6000111I199 T200 S201 A206 I207I199-D203 WeakPolarHBondContact CA-OD2 3.36Å; T200-D203 PolarHBondContact N-OD2 2.98Å; T200-D203 WeakPolarHBondContact O-CB 3.4Å; T200-D203 PolarHBondContact O-N 3.26Å; S201-D203 PolarHBondContact O-N 3.05Å; D203-A206 PolarHBondContact O-N 2.97Å; D203-I207 WeakPolarHBondContact O-CG1 3.46Å; D203-I207 PolarHBondContact O-N 3.11Å
204I98.3Very high94.4Very high0 Ų053 Ų530%031%0.313CS..Hα-helixtrans-66.3-45.7178.1-57.4-54.2000110.9L145 I151 I155 I170 L172 I199 T200 S201 A206 I207 L208 I288L145-I204 HydrophobicContact CD1-CD1 3.99Å; I151-I204 HydrophobicContact CG2-CD1 3.6Å; I155-I204 HydrophobicContact CD1-CD1 4.06Å; I155-I204 HydrophobicContact CD1-CG2 4Å; I170-I204 HydrophobicContact CD1-CG2 4.22Å; L172-I204 HydrophobicContact CD1-CB 4.48Å; L172-I204 HydrophobicContact CD1-CD1 4.39Å; L172-I204 HydrophobicContact CD1-CG1 3.43Å; L172-I204 VanDerWaalsContact CD1-CG1 3.43Å; L172-I204 HydrophobicContact CD2-CG1 4.32Å; I199-I204 HydrophobicContact CD1-CD1 4.28Å; T200-I204 PolarHBondContact O-N 3.14Å; S201-I204 PolarHBondContact O-N 2.57Å; I204-A206 VanDerWaalsContact C-N 3.28Å; I204-A206 PolarHBondContact O-N 2.85Å; I204-I207 HydrophobicContact CD1-CD1 4.28Å; I204-I207 WeakPolarHBondContact O-CB 3.26Å; I204-I207 PolarHBondContact O-N 2.78Å; I204-I207 VanDerWaalsContact O-N 3.14Å; I204-L208 HydrophobicContact CG2-CD1 3.95Å; I204-L208 HydrophobicContact CG2-CG 4.21Å; I204-L208 VanDerWaalsContact O-CG 3.26Å; I204-L208 WeakPolarHBondContact O-CG 3.27Å; I204-L208 PolarHBondContact O-N 3.41Å; I204-I288 HydrophobicContact CB-CD1 3.67Å; I204-I288 HydrophobicContact CG2-CD1 3.49Å; I204-I288 VanDerWaalsContact CG2-CD1 3.49Å
205E98.1Very high95.4Very high53 Ų5349.1 Ų49.125%0.24829%0.291CS..Hα-helixtrans-57.7-41.2174.3-78.4-171.1102.600111.6S201 I207 L208 N209 H215 L217 I288S201-E205 WeakPolarHBondContact O-CB 3.4Å; S201-E205 WeakPolarHBondContact O-CG 3.4Å; S201-E205 PolarHBondContact O-N 2.92Å; E205-I207 VanDerWaalsContact C-N 3.35Å; E205-I207 PolarHBondContact O-N 3.22Å; E205-L208 PolarHBondContact O-N 2.98Å; E205-N209 VanDerWaalsContact O-CB 3.24Å; E205-N209 WeakPolarHBondContact O-CB 3.26Å; E205-N209 VanDerWaalsContact O-CG 3.23Å; E205-N209 PolarHBondContact O-N 3.18Å; E205-N209 PolarHBondContact O-ND2 2.81Å; E205-H215 IonicContact OE1-NE2 3.82Å; E205-L217 HydrophobicContact CG-CD1 4.42Å; E205-I288 HydrophobicContact CG-CD1 4.44Å
206A98.2Very high96.4Very high54 Ų5449.3 Ų49.345%0.44629%0.29SS..Hα-helixtrans-61.8-41.417600000112.3A202 D203 I204 S210A202-A206 WeakPolarHBondContact O-CB 3.33Å; A202-A206 PolarHBondContact O-N 2.83Å; D203-A206 PolarHBondContact O-N 2.97Å; I204-A206 VanDerWaalsContact C-N 3.28Å; I204-A206 PolarHBondContact O-N 2.85Å; A206-S210 VanDerWaalsContact O-CB 3.31Å; A206-S210 WeakPolarHBondContact O-CB 3.45Å; A206-S210 PolarHBondContact O-N 3.46Å; A206-S210 PolarHBondContact O-OG 3.48Å
207I98Very high97.1Very high41 Ų4151.7 Ų51.721%0.2130%0.302CS..Hα-helixtrans-62.2-47.6174.9-68.7164.1000110.7I151 P152 D203 I204 E205 S210 A211I151-I207 HydrophobicContact CG2-CD1 4.02Å; P152-I207 HydrophobicContact CB-CG2 4.06Å; P152-I207 HydrophobicContact CG-CD1 3.92Å; P152-I207 HydrophobicContact CG-CG1 4.15Å; P152-I207 HydrophobicContact CG-CG2 4.25Å; D203-I207 WeakPolarHBondContact O-CG1 3.46Å; D203-I207 PolarHBondContact O-N 3.11Å; I204-I207 HydrophobicContact CD1-CD1 4.28Å; I204-I207 WeakPolarHBondContact O-CB 3.26Å; I204-I207 PolarHBondContact O-N 2.78Å; I204-I207 VanDerWaalsContact O-N 3.14Å; E205-I207 VanDerWaalsContact C-N 3.35Å; E205-I207 PolarHBondContact O-N 3.22Å; I207-S210 PolarHBondContact O-N 2.98Å; I207-A211 WeakPolarHBondContact O-CB 3.4Å; I207-A211 PolarHBondContact O-N 2.8Å; I207-A211 VanDerWaalsContact O-N 3.07Å
208L98.3Very high97.6Very high0 Ų051.3 Ų51.30%030%0.299CS..Hα-helixtrans-66.2-44.1-178.2-65.2175.2000112I155 I204 E205 S210 A211 G212 L213 H215 I288 I290I155-L208 HydrophobicContact CG2-CD2 3.76Å; I204-L208 HydrophobicContact CG2-CD1 3.95Å; I204-L208 HydrophobicContact CG2-CG 4.21Å; I204-L208 VanDerWaalsContact O-CG 3.26Å; I204-L208 WeakPolarHBondContact O-CG 3.27Å; I204-L208 PolarHBondContact O-N 3.41Å; E205-L208 PolarHBondContact O-N 2.98Å; L208-S210 VanDerWaalsContact C-N 3.34Å; L208-S210 PolarHBondContact O-N 2.76Å; L208-A211 CarbonylContact O-C 3.59Å; L208-A211 PolarHBondContact O-N 2.95Å; L208-A211 VanDerWaalsContact O-N 3.15Å; L208-G212 PolarHBondContact O-N 3.46Å; L208-L213 HydrophobicContact CB-CB 4.42Å; L208-L213 HydrophobicContact CD2-CB 4.17Å; L208-L213 HydrophobicContact CD2-CD1 3.75Å; L208-L213 PolarHBondContact O-N 2.59Å; L208-H215 HydrophobicContact CD1-CB 4.05Å; L208-I288 HydrophobicContact CD1-CG2 3.59Å; L208-I290 HydrophobicContact CD1-CD1 3.84Å; L208-I290 HydrophobicContact CD1-CG1 3.9Å; L208-I290 HydrophobicContact CD2-CD1 3.6Å; L208-I290 HydrophobicContact CD2-CG1 4.2Å; L208-I290 HydrophobicContact CG-CD1 4.38Å
209N98Very high97.8Very high103 Ų10353.5 Ų53.555%0.55131%0.311SS*.Hα-helixtrans-60.5-44.3175.9-77.8-43000111.4E205 A211 G212 H215E205-N209 VanDerWaalsContact O-CB 3.24Å; E205-N209 WeakPolarHBondContact O-CB 3.26Å; E205-N209 VanDerWaalsContact O-CG 3.23Å; E205-N209 PolarHBondContact O-N 3.18Å; E205-N209 PolarHBondContact O-ND2 2.81Å; N209-A211 PolarHBondContact O-N 3.24Å; N209-G212 PolarHBondContact O-N 3.05Å; N209-H215 PolarHBondContact OD1-CE1 2.96Å; N209-H215 VanDerWaalsContact OD1-CE1 3.32Å
210S97.4Very high98Very high111 Ų11153.2 Ų53.278%0.77631%0.309SS*.Hα-helixtrans-64.1-29.6177.1-600000112.6A206 I207 L208A206-S210 VanDerWaalsContact O-CB 3.31Å; A206-S210 WeakPolarHBondContact O-CB 3.45Å; A206-S210 PolarHBondContact O-N 3.46Å; A206-S210 PolarHBondContact O-OG 3.48Å; I207-S210 PolarHBondContact O-N 2.98Å; L208-S210 VanDerWaalsContact C-N 3.34Å; L208-S210 PolarHBondContact O-N 2.76Å
211A96.3Very high97.9Very high54 Ų5458.1 Ų58.145%0.44634%0.341SS..THydrogen-bonded Turntrans-86.4-4.4175.700000113.8I207 L208 N209 L213I207-A211 WeakPolarHBondContact O-CB 3.4Å; I207-A211 PolarHBondContact O-N 2.8Å; I207-A211 VanDerWaalsContact O-N 3.07Å; L208-A211 CarbonylContact O-C 3.59Å; L208-A211 PolarHBondContact O-N 2.95Å; L208-A211 VanDerWaalsContact O-N 3.15Å; N209-A211 PolarHBondContact O-N 3.24Å; A211-L213 HydrophobicContact CB-CD1 4.15Å; A211-L213 HydrophobicContact CB-CG 3.89Å; A211-L213 PolarHBondContact O-N 2.8Å
212G97.3Very high97.9Very high66 Ų6658.2 Ų58.268%0.6834%0.342SS*.THydrogen-bonded Turntrans67.322.8-17600000114L208 N209L208-G212 PolarHBondContact O-N 3.46Å; N209-G212 PolarHBondContact O-N 3.05Å
213L97.7Very high97.9Very high31 Ų3159 Ų5916%0.16234%0.339CS..  trans-83124.3-178.4-64.3-178.5000110.6L208 A211 H215 I290L208-L213 HydrophobicContact CB-CB 4.42Å; L208-L213 HydrophobicContact CD2-CB 4.17Å; L208-L213 HydrophobicContact CD2-CD1 3.75Å; L208-L213 PolarHBondContact O-N 2.59Å; A211-L213 HydrophobicContact CB-CD1 4.15Å; A211-L213 HydrophobicContact CB-CG 3.89Å; A211-L213 PolarHBondContact O-N 2.8Å; L213-H215 PolarHBondContact O-N 3.42Å; L213-H215 PolarHBondContact O-ND1 2.94Å; L213-I290 HydrophobicContact CB-CG2 4.3Å
214K98.1Very high97.9Very high154 Ų15455.9 Ų55.967%0.6732%0.322SS*.  trans-70.4126.2176.7-178.9178.4172.5-167.90109.7E291K214-E291 HydrophobicContact CB-CB 4.19Å; K214-E291 HydrophobicContact CB-CG 4.23Å; K214-E291 HydrophobicContact CD-CG 3.95Å; K214-E291 HydrophobicContact CG-CB 4.45Å; K214-E291 HydrophobicContact CG-CG 3.93Å; K214-E291 PolarHBondContact O-N 2.73Å
215H98.5Very high97.9Very high42 Ų4257 Ų5719%0.19433%0.328CS..EExtended strand (participates in β ladder)trans-144.4164.9-179.460.7-80000112E205 L208 N209 L213 I288 V289 I290E205-H215 IonicContact OE1-NE2 3.82Å; L208-H215 HydrophobicContact CD1-CB 4.05Å; N209-H215 PolarHBondContact OD1-CE1 2.96Å; N209-H215 VanDerWaalsContact OD1-CE1 3.32Å; L213-H215 PolarHBondContact O-N 3.42Å; L213-H215 PolarHBondContact O-ND1 2.94Å; H215-I288 HydrophobicContact CB-CG2 4.03Å; H215-V289 CarbonylContact C-O 3.55Å; H215-V289 WeakPolarHBondContact CA-O 3.36Å; H215-V289 WeakPolarHBondContact CB-O 3.31Å; H215-I290 HydrophobicContact CB-CG1 4.14Å
216Q98.4Very high98Very high103 Ų10354.5 Ų54.548%0.48132%0.316SS..EExtended strand (participates in β ladder)trans-129.7133.8172.2-178.7171.7100109.4Y218 I288 V289Q216-Y218 HydrophobicContact CB-CE2 4.21Å; Q216-Y218 VanDerWaalsContact CD-CZ 3.41Å; Q216-Y218 HydrophobicContact CG-CD2 4.31Å; Q216-Y218 HydrophobicContact CG-CE2 3.67Å; Q216-Y218 PolarHBondContact NE2-OH 3.5Å; Q216-Y218 PolarHBondContact OE1-OH 3.04Å; Q216-Y218 VanDerWaalsContact OE1-OH 3.1Å; Q216-I288 WeakPolarHBondContact O-CA 3.44Å; Q216-V289 PolarHBondContact N-O 3.35Å; Q216-V289 PolarHBondContact O-N 3.12Å
217L98.3Very high98Very high55 Ų5553.9 Ų53.929%0.28831%0.307SS..EExtended strand (participates in β ladder)trans-100.4138.9176.4-171.877.3000110.3E205 V287 I288E205-L217 HydrophobicContact CG-CD1 4.42Å; L217-V287 CarbonylContact C-O 3.51Å; L217-V287 WeakPolarHBondContact CA-O 3.49Å; L217-I288 HydrophobicContact CD1-CD1 4.22Å; L217-I288 HydrophobicContact CD1-CG1 3.5Å; L217-I288 VanDerWaalsContact CD1-CG1 3.5Å
218Y98.3Very high98Very high44 Ų4452.8 Ų52.817%0.17330%0.303CS..EExtended strand (participates in β ladder)trans-125.4128168.8-56.3-101.5000108.5F35 Q39 Q216 L220 S286 V287 V289F35-Y218 HydrophobicContact CD2-CG 4.44Å; F35-Y218 HydrophobicContact CE2-CD1 4.09Å; F35-Y218 AromaticContact CE2-CD2 3.9Å; F35-Y218 HydrophobicContact CE2-CD2 3.9Å; F35-Y218 HydrophobicContact CE2-CE1 4.5Å; F35-Y218 HydrophobicContact CE2-CE2 4.34Å; F35-Y218 AromaticContact CE2-CG 3.76Å; F35-Y218 HydrophobicContact CE2-CG 3.76Å; F35-Y218 HydrophobicContact CZ-CD2 4.5Å; Q39-Y218 HydrophobicContact CB-CE1 4.49Å; Q39-Y218 HydrophobicContact CG-CD1 4.48Å; Q216-Y218 HydrophobicContact CB-CE2 4.21Å; Q216-Y218 VanDerWaalsContact CD-CZ 3.41Å; Q216-Y218 HydrophobicContact CG-CD2 4.31Å; Q216-Y218 HydrophobicContact CG-CE2 3.67Å; Q216-Y218 PolarHBondContact NE2-OH 3.5Å; Q216-Y218 PolarHBondContact OE1-OH 3.04Å; Q216-Y218 VanDerWaalsContact OE1-OH 3.1Å; Y218-L220 VanDerWaalsContact O-CD1 3.29Å; Y218-L220 WeakPolarHBondContact O-CD1 3.22Å; Y218-S286 CarbonylContact O-C 3.54Å; Y218-S286 VanDerWaalsContact O-CA 3.24Å; Y218-S286 WeakPolarHBondContact O-CA 3.49Å; Y218-V287 HydrophobicContact CD2-CB 4.45Å; Y218-V287 PolarHBondContact N-O 3.31Å; Y218-V287 PolarHBondContact O-N 3.05Å; Y218-V289 HydrophobicContact CD2-CG2 4.28Å; Y218-V289 HydrophobicContact CE2-CB 4.37Å; Y218-V289 HydrophobicContact CE2-CG2 3.74Å
219E97.9Very high98Very high86 Ų8653.3 Ų53.340%0.40231%0.306SS..EExtended strand (participates in β ladder)trans-89.1133.9173.5-73.3-61.9128.800110.6S174 S286S174-E219 VanDerWaalsContact CB-OE2 3.23Å; S174-E219 WeakPolarHBondContact CB-OE2 3.18Å; S174-E219 VanDerWaalsContact OG-CD 3.3Å; S174-E219 PolarHBondContact OG-OE1 3.24Å; S174-E219 PolarHBondContact OG-OE2 3.16Å; E219-S286 WeakPolarHBondContact OE1-CB 3.42Å; E219-S286 PolarHBondContact OE1-OG 3.12Å
220L97.8Very high97.9Very high9 Ų950.6 Ų50.65%0.04729%0.289CS..EExtended strand (participates in β ladder)trans-11999.1-178.1-76.764.9000107.9C31 F35 Y218 S222 N284 L285 V287C31-L220 HydrophobicContact CB-CB 4.25Å; F35-L220 HydrophobicContact CB-CD2 3.78Å; F35-L220 HydrophobicContact CB-CG 4.2Å; F35-L220 HydrophobicContact CD2-CD1 4.2Å; F35-L220 HydrophobicContact CG-CD2 4.35Å; Y218-L220 VanDerWaalsContact O-CD1 3.29Å; Y218-L220 WeakPolarHBondContact O-CD1 3.22Å; L220-S222 PolarHBondContact O-N 2.79Å; L220-N284 WeakPolarHBondContact O-CA 3.5Å; L220-L285 HydrophobicContact CB-CB 4.09Å; L220-L285 PolarHBondContact N-O 2.92Å; L220-L285 PolarHBondContact O-N 3.18Å; L220-V287 HydrophobicContact CD1-CB 4.14Å; L220-V287 HydrophobicContact CD1-CG2 3.5Å; L220-V287 VanDerWaalsContact CD1-CG2 3.5Å; L220-V287 HydrophobicContact CD2-CG2 3.68Å; L220-V287 HydrophobicContact CG-CG2 4.27Å
221P97.4Very high97.9Very high103 Ų10348.9 Ų48.967%0.66928%0.275SS*.  trans-55.7128175.3-2635.5000111.1C31 N284C31-P221 WeakPolarHBondContact CB-O 3.3Å; P221-N284 VanDerWaalsContact CA-OD1 3.29Å; P221-N284 WeakPolarHBondContact CA-OD1 3.18Å
222S98.2Very high97.7Very high5 Ų555.7 Ų55.74%0.03530%0.297CS..  trans-153.5151.1-179.9179.50000110.5T27 L220 N283 N284T27-S222 VanDerWaalsContact OG1-CA 3.3Å; T27-S222 WeakPolarHBondContact OG1-CA 3.48Å; T27-S222 PolarHBondContact OG1-OG 2.92Å; L220-S222 PolarHBondContact O-N 2.79Å; S222-N283 VanDerWaalsContact CB-O 3.26Å; S222-N283 WeakPolarHBondContact CB-O 3.13Å; S222-N283 CarbonylContact O-C 3.57Å; S222-N283 WeakPolarHBondContact O-CA 3.19Å; S222-N283 PolarHBondContact O-N 3.13Å; S222-N283 PolarHBondContact OG-ND2 3.44Å; S222-N283 VanDerWaalsContact OG-ND2 3.13Å; S222-N284 PolarHBondContact N-OD1 2.92Å; S222-N284 PolarHBondContact O-N 2.8Å; S222-N284 PolarHBondContact O-OD1 3.31Å
223H97.6Very high97.4Very high59 Ų5955.5 Ų55.527%0.27330%0.295SS..EExtended strand (participates in β ladder)trans-135.9156.1-179.656.1-80.8000111.7S26 T27 L280 F281S26-H223 CarbonylContact C-O 3.56Å; S26-H223 WeakPolarHBondContact CA-O 3.43Å; S26-H223 WeakPolarHBondContact CB-O 3.39Å; T27-H223 WeakPolarHBondContact CG2-CE1 3.45Å; T27-H223 PolarHBondContact N-O 3.38Å; T27-H223 PolarHBondContact OG1-N 3.35Å; T27-H223 PolarHBondContact OG1-O 3.03Å; H223-L280 HydrophobicContact CB-CB 4.2Å; H223-F281 CarbonylContact C-O 3.55Å; H223-F281 VanDerWaalsContact CA-O 3.24Å; H223-F281 WeakPolarHBondContact CA-O 3.24Å
224M98.6Very high97.4Very high0 Ų056.7 Ų56.70%030%0.302CS..EExtended strand (participates in β ladder)trans-125.4120.3174.3175.5-168.6-178.800108.4F22 N25 W179 I226 L240 F243 L244 L280 F281 N283F22-M224 HydrophobicContact CB-CE 4.44Å; F22-M224 HydrophobicContact CD2-CE 4.02Å; F22-M224 HydrophobicContact CD2-CG 4.19Å; F22-M224 HydrophobicContact CD2-SD 3.82Å; F22-M224 HydrophobicContact CE2-SD 4.28Å; N25-M224 CarbonylContact O-C 3.28Å; N25-M224 WeakPolarHBondContact O-CA 3.47Å; W179-M224 HydrophobicContact CZ2-SD 4.49Å; M224-I226 HydrophobicContact CE-CG2 4.07Å; M224-I226 HydrophobicContact CG-CG2 3.86Å; M224-I226 PolarHBondContact O-N 2.96Å; M224-I226 HydrophobicContact SD-CG2 3.93Å; M224-L240 HydrophobicContact CE-CB 3.98Å; M224-L240 HydrophobicContact CE-CD1 4.39Å; M224-L240 HydrophobicContact CE-CD2 3.16Å; M224-L240 HydrophobicContact CE-CG 4Å; M224-F243 HydrophobicContact CE-CD1 4.25Å; M224-L244 HydrophobicContact CE-CD2 4.45Å; M224-L244 HydrophobicContact CE-CG 4.24Å; M224-L244 HydrophobicContact SD-CD2 4.06Å; M224-L244 HydrophobicContact SD-CG 4.48Å; M224-L280 CarbonylContact O-C 3.47Å; M224-F281 HydrophobicContact CB-CB 4.25Å; M224-F281 HydrophobicContact CB-CD1 4.5Å; M224-F281 PolarHBondContact N-O 2.92Å; M224-F281 PolarHBondContact O-N 3.35Å; M224-F281 HydrophobicContact SD-CD1 4.47Å; M224-N283 HydrophobicContact CB-CB 4.19Å
225D98.6Very high97.3Very high24 Ų2454.3 Ų54.313%0.12830%0.3CS..EExtended strand (participates in β ladder)trans-73.4106.7176.5-171.6-17000109.4N25 T227 K278 L280N25-D225 PolarHBondContact O-N 3.27Å; D225-T227 WeakPolarHBondContact OD1-CB 3.26Å; D225-T227 PolarHBondContact OD1-N 3.1Å; D225-T227 PolarHBondContact OD1-OG1 3Å; D225-K278 WeakPolarHBondContact OD2-CD 3.47Å; D225-K278 WeakPolarHBondContact OD2-CE 3.38Å; D225-K278 IonicContact OD2-NZ 3.36Å; D225-K278 PolarHBondContact OD2-NZ 3.31Å; D225-L280 HydrophobicContact CB-CD2 4.04Å
226I98.6Very high97.3Very high0 Ų054.7 Ų54.70%030%0.303CS..  trans-106.717.3-178.861.8158.7000111.5M224 S228 C229 F230 L244 L266 V279 F281M224-I226 HydrophobicContact CE-CG2 4.07Å; M224-I226 HydrophobicContact CG-CG2 3.86Å; M224-I226 PolarHBondContact O-N 2.96Å; M224-I226 HydrophobicContact SD-CG2 3.93Å; I226-S228 PolarHBondContact O-N 3.27Å; I226-C229 WeakPolarHBondContact O-CB 3.46Å; I226-C229 PolarHBondContact O-N 2.81Å; I226-C229 PolarHBondContact O-SG 2.84Å; I226-F230 HydrophobicContact CD1-CE2 3.99Å; I226-F230 HydrophobicContact CD1-CZ 4.2Å; I226-F230 HydrophobicContact CG1-CE2 4.17Å; I226-F230 WeakPolarHBondContact O-CD2 3.34Å; I226-F230 WeakPolarHBondContact O-CE2 3.49Å; I226-L244 HydrophobicContact CG2-CD1 3.9Å; I226-L266 HydrophobicContact CD1-CB 3.93Å; I226-L266 HydrophobicContact CD1-CD2 4.31Å; I226-L266 HydrophobicContact CD1-CG 4.5Å; I226-V279 HydrophobicContact CD1-CG1 3.87Å; I226-V279 HydrophobicContact CG1-CB 4.04Å; I226-V279 HydrophobicContact CG1-CG1 3.75Å; I226-V279 WeakPolarHBondContact CG1-O 3.43Å; I226-V279 PolarHBondContact N-O 2.88Å; I226-F281 HydrophobicContact CD1-CB 3.98Å; I226-F281 HydrophobicContact CD1-CD2 4.47Å; I226-F281 HydrophobicContact CG1-CB 4.04Å; I226-F281 HydrophobicContact CG2-CB 3.81Å
227T98.4Very high97.3Very high42 Ų4249.8 Ų49.826%0.25828%0.281SS..G310 helixtrans-57.6-38.9-177.8-53.30000111.7D225 C229 F230 K278 V279D225-T227 WeakPolarHBondContact OD1-CB 3.26Å; D225-T227 PolarHBondContact OD1-N 3.1Å; D225-T227 PolarHBondContact OD1-OG1 3Å; T227-C229 PolarHBondContact O-N 2.83Å; T227-F230 PolarHBondContact O-N 3.06Å; T227-F230 VanDerWaalsContact O-N 3.17Å; T227-K278 VanDerWaalsContact OG1-CA 3.28Å; T227-K278 WeakPolarHBondContact OG1-CA 3.3Å; T227-V279 PolarHBondContact OG1-N 2.85Å
228S98.1Very high97.2Very high18 Ų1849.4 Ų49.413%0.12628%0.278CS..G310 helixtrans-63.2-26.717954.60000113.2I226 F230 T231 G237I226-S228 PolarHBondContact O-N 3.27Å; S228-F230 PolarHBondContact O-N 2.8Å; S228-F230 VanDerWaalsContact O-N 3.16Å; S228-T231 PolarHBondContact O-N 2.82Å; S228-G237 WeakPolarHBondContact OG-CA 3.48Å; S228-G237 PolarHBondContact OG-N 2.8Å
229C98.1Very high97.2Very high10 Ų1048 Ų487%0.06827%0.273CS..G310 helixtrans-59.6-26.3176.3-59.80000112.4I226 T227 L240 L241 M263I226-C229 WeakPolarHBondContact O-CB 3.46Å; I226-C229 PolarHBondContact O-N 2.81Å; I226-C229 PolarHBondContact O-SG 2.84Å; T227-C229 PolarHBondContact O-N 2.83Å; C229-L240 VanDerWaalsContact SG-CB 3.6Å; C229-L241 HydrophobicContact CB-CD1 4.28Å; C229-L241 HydrophobicContact CB-CD2 3.88Å; C229-L241 HydrophobicContact CB-CG 3.84Å; C229-M263 WeakPolarHBondContact O-CE 3.36Å
230F97Very high97.3Very high46 Ų4644 Ų4420%0.20225%0.254CS..G310 helixtrans-92.94.2-179.6-55.4-77.2000113.7I226 T227 S228 M263 L266 R267 V279I226-F230 HydrophobicContact CD1-CE2 3.99Å; I226-F230 HydrophobicContact CD1-CZ 4.2Å; I226-F230 HydrophobicContact CG1-CE2 4.17Å; I226-F230 WeakPolarHBondContact O-CD2 3.34Å; I226-F230 WeakPolarHBondContact O-CE2 3.49Å; T227-F230 PolarHBondContact O-N 3.06Å; T227-F230 VanDerWaalsContact O-N 3.17Å; S228-F230 PolarHBondContact O-N 2.8Å; S228-F230 VanDerWaalsContact O-N 3.16Å; F230-M263 HydrophobicContact CD1-CE 3.36Å; F230-M263 HydrophobicContact CE1-CE 3.59Å; F230-M263 WeakPolarHBondContact CE1-O 3.31Å; F230-M263 HydrophobicContact CG-CE 4.16Å; F230-L266 HydrophobicContact CZ-CB 4.04Å; F230-R267 VanDerWaalsContact CB-NH2 3.33Å; F230-R267 HydrophobicContact CD1-CG 4.33Å; F230-R267 HydrophobicContact CE1-CG 3.49Å; F230-R267 VanDerWaalsContact CE1-CG 3.49Å; F230-R267 VanDerWaalsContact CE1-NE 3.27Å; F230-R267 HydrophobicContact CE2-CG 4.17Å; F230-R267 VanDerWaalsContact CG-NH2 3.3Å; F230-R267 HydrophobicContact CZ-CG 3.39Å; F230-V279 HydrophobicContact CD2-CB 4.42Å; F230-V279 HydrophobicContact CD2-CG2 4.06Å; F230-V279 HydrophobicContact CE2-CB 3.9Å; F230-V279 HydrophobicContact CE2-CG1 3.84Å; F230-V279 HydrophobicContact CE2-CG2 3.86Å; F230-V279 HydrophobicContact CZ-CG1 4.38Å
231T96.3Very high97.3Very high76 Ų7643.7 Ų43.747%0.46625%0.252SS..SBendtrans-104.9110.8177-56.40000109.3S228 G233 N234S228-T231 PolarHBondContact O-N 2.82Å; T231-G233 PolarHBondContact O-N 3.1Å; T231-N234 HydrophobicContact CG2-CB 4.14Å; T231-N234 VanDerWaalsContact O-CB 3.27Å; T231-N234 WeakPolarHBondContact O-CB 3.24Å; T231-N234 PolarHBondContact O-N 2.85Å; T231-N234 VanDerWaalsContact O-N 3.11Å
232E91.8Very high97.3Very high197 Ų19738.8 Ų38.892%0.92122%0.221SC*.THydrogen-bonded Turntrans-56.3128.9-178.7-171.7175.9-174.300111.6N234E232-N234 VanDerWaalsContact C-N 3.28Å; E232-N234 PolarHBondContact O-N 2.94Å
233G91.3Very high97.2Very high61 Ų6139.2 Ų39.263%0.62922%0.222SC*.THydrogen-bonded Turntrans78.52.9178.900000115.3T231 T235T231-G233 PolarHBondContact O-N 3.1Å; G233-T235 PolarHBondContact O-N 3.23Å
234N97.5Very high97.2Very high57 Ų5736.4 Ų36.431%0.30521%0.209SC..  trans-71.9116175.7-173.7-63.6000111.2T231 E232 D236 G237 E238T231-N234 HydrophobicContact CG2-CB 4.14Å; T231-N234 VanDerWaalsContact O-CB 3.27Å; T231-N234 WeakPolarHBondContact O-CB 3.24Å; T231-N234 PolarHBondContact O-N 2.85Å; T231-N234 VanDerWaalsContact O-N 3.11Å; E232-N234 VanDerWaalsContact C-N 3.28Å; E232-N234 PolarHBondContact O-N 2.94Å; N234-D236 PolarHBondContact O-N 3.47Å; N234-D236 PolarHBondContact OD1-N 2.86Å; N234-G237 PolarHBondContact O-N 2.81Å; N234-G237 VanDerWaalsContact O-N 3.15Å; N234-G237 PolarHBondContact OD1-N 2.6Å; N234-E238 WeakPolarHBondContact O-CG 3.18Å; N234-E238 PolarHBondContact O-N 2.95Å
235T97Very high97Very high103 Ų10336.4 Ų36.463%0.63221%0.209SC*.Hα-helixtrans-59.9-42-176.1-50.60000113.8G233 G237 E238 L239G233-T235 PolarHBondContact O-N 3.23Å; T235-G237 VanDerWaalsContact C-N 3.35Å; T235-E238 PolarHBondContact O-N 3.27Å; T235-L239 WeakPolarHBondContact O-CG 3.39Å; T235-L239 PolarHBondContact O-N 3.49Å; T235-L239 VanDerWaalsContact O-N 3.14Å
236D97.9Very high96.8Very high50 Ų5036 Ų3627%0.26721%0.206SC..Hα-helixtrans-67-40.6177.8-75.47.1000110I21 N234 E238 L239 L240I21-D236 HydrophobicContact CG2-CB 3.89Å; N234-D236 PolarHBondContact O-N 3.47Å; N234-D236 PolarHBondContact OD1-N 2.86Å; D236-E238 PolarHBondContact O-N 3.04Å; D236-L239 PolarHBondContact O-N 3.18Å; D236-L240 VanDerWaalsContact O-CG 3.3Å; D236-L240 WeakPolarHBondContact O-CG 3.29Å; D236-L240 PolarHBondContact O-N 3.32Å
237G98.1Very high96.7Very high1 Ų136 Ų361%0.0121%0.206CC..Hα-helixtrans-60-42.6175.400000113.2S228 N234 T235 L239 L240 L241S228-G237 WeakPolarHBondContact OG-CA 3.48Å; S228-G237 PolarHBondContact OG-N 2.8Å; N234-G237 PolarHBondContact O-N 2.81Å; N234-G237 VanDerWaalsContact O-N 3.15Å; N234-G237 PolarHBondContact OD1-N 2.6Å; T235-G237 VanDerWaalsContact C-N 3.35Å; G237-L239 PolarHBondContact O-N 3.19Å; G237-L240 PolarHBondContact O-N 2.88Å; G237-L241 WeakPolarHBondContact O-CG 3.13Å; G237-L241 PolarHBondContact O-N 3.26Å
238E97.8Very high96.5Very high47 Ų4734.6 Ų34.622%0.2220%0.198CC..Hα-helixtrans-62.9-41.3175.4-64.8-63.2167.400112N234 T235 D236 L241 D242 S251N234-E238 WeakPolarHBondContact O-CG 3.18Å; N234-E238 PolarHBondContact O-N 2.95Å; T235-E238 PolarHBondContact O-N 3.27Å; D236-E238 PolarHBondContact O-N 3.04Å; E238-L241 PolarHBondContact O-N 3.41Å; E238-D242 PolarHBondContact O-N 3.31Å; E238-D242 VanDerWaalsContact O-N 3.09Å; E238-S251 WeakPolarHBondContact OE2-CB 3.37Å; E238-S251 PolarHBondContact OE2-OG 3.46Å
239L98.3Very high96.3Very high15 Ų1537.1 Ų37.18%0.07921%0.208CC..Hα-helixtrans-68.4-35.3177-73.7171.4000112.7E17 S18 I21 T235 D236 G237 D242 F243E17-L239 HydrophobicContact CB-CD1 4.47Å; E17-L239 HydrophobicContact CB-CD2 4.18Å; S18-L239 WeakPolarHBondContact CB-O 3.23Å; S18-L239 PolarHBondContact OG-O 2.74Å; I21-L239 HydrophobicContact CB-CB 4.49Å; I21-L239 HydrophobicContact CG1-CB 4.27Å; I21-L239 HydrophobicContact CG1-CD1 3.72Å; T235-L239 WeakPolarHBondContact O-CG 3.39Å; T235-L239 PolarHBondContact O-N 3.49Å; T235-L239 VanDerWaalsContact O-N 3.14Å; D236-L239 PolarHBondContact O-N 3.18Å; G237-L239 PolarHBondContact O-N 3.19Å; L239-D242 PolarHBondContact O-N 2.91Å; L239-F243 PolarHBondContact O-N 2.84Å; L239-F243 VanDerWaalsContact O-N 3.15Å
240L98.4Very high96.2Very high0 Ų036.7 Ų36.70%021%0.205CC..Hα-helixtrans-70.9-37.4175.4-69.9176.3000112.1I21 F22 N25 M224 C229 D236 G237 D242 F243 L244I21-L240 HydrophobicContact CB-CD2 4.27Å; I21-L240 HydrophobicContact CG2-CD1 4.28Å; I21-L240 HydrophobicContact CG2-CD2 3.71Å; I21-L240 HydrophobicContact CG2-CG 3.75Å; F22-L240 HydrophobicContact CB-CD2 4.33Å; N25-L240 HydrophobicContact CB-CD1 4.4Å; M224-L240 HydrophobicContact CE-CB 3.98Å; M224-L240 HydrophobicContact CE-CD1 4.39Å; M224-L240 HydrophobicContact CE-CD2 3.16Å; M224-L240 HydrophobicContact CE-CG 4Å; C229-L240 VanDerWaalsContact SG-CB 3.6Å; D236-L240 VanDerWaalsContact O-CG 3.3Å; D236-L240 WeakPolarHBondContact O-CG 3.29Å; D236-L240 PolarHBondContact O-N 3.32Å; G237-L240 PolarHBondContact O-N 2.88Å; L240-D242 VanDerWaalsContact C-N 3.31Å; L240-F243 WeakPolarHBondContact O-CB 3.16Å; L240-F243 PolarHBondContact O-N 3.02Å; L240-L244 WeakPolarHBondContact O-CG 3.23Å; L240-L244 PolarHBondContact O-N 3.04Å
241L97.8Very high96.1Very high3 Ų335.2 Ų35.22%0.01620%0.201CC..Hα-helixtrans-62.3-41.2172.6-76.6174.4000111.7C229 G237 E238 F243 L244 T245 F250 S251 M263 L266C229-L241 HydrophobicContact CB-CD1 4.28Å; C229-L241 HydrophobicContact CB-CD2 3.88Å; C229-L241 HydrophobicContact CB-CG 3.84Å; G237-L241 WeakPolarHBondContact O-CG 3.13Å; G237-L241 PolarHBondContact O-N 3.26Å; E238-L241 PolarHBondContact O-N 3.41Å; L241-F243 VanDerWaalsContact C-N 3.26Å; L241-F243 PolarHBondContact O-N 3.27Å; L241-L244 PolarHBondContact O-N 3.3Å; L241-T245 WeakPolarHBondContact O-CB 3.32Å; L241-T245 WeakPolarHBondContact O-CG2 3.45Å; L241-T245 PolarHBondContact O-N 3.05Å; L241-T245 PolarHBondContact O-OG1 3.33Å; L241-F250 HydrophobicContact CB-CD1 4.35Å; L241-S251 WeakPolarHBondContact CD1-OG 3.24Å; L241-M263 HydrophobicContact CD1-SD 4.02Å; L241-M263 HydrophobicContact CD2-SD 3.56Å; L241-M263 VanDerWaalsContact CD2-SD 3.56Å; L241-M263 HydrophobicContact CG-SD 4.44Å; L241-L266 HydrophobicContact CD2-CD1 3.94Å
242D97.2Very high96Very high0 Ų038.6 Ų38.60%021%0.209CC..Hα-helixtrans-60.6-38.9174.8-74.15.1000112L8 R14 E238 L239 L240 E246 T247 E249 F250L8-D242 HydrophobicContact CD1-CB 4.34Å; R14-D242 IonicContact CZ-OD2 3.93Å; R14-D242 IonicContact NE-OD2 3.81Å; R14-D242 PolarHBondContact NE-OD2 3.05Å; R14-D242 IonicContact NH2-OD2 2.75Å; R14-D242 PolarHBondContact NH2-OD2 3.2Å; E238-D242 PolarHBondContact O-N 3.31Å; E238-D242 VanDerWaalsContact O-N 3.09Å; L239-D242 PolarHBondContact O-N 2.91Å; L240-D242 VanDerWaalsContact C-N 3.31Å; D242-E246 CarbonylContact O-C 3.54Å; D242-E246 VanDerWaalsContact O-CA 3.28Å; D242-E246 WeakPolarHBondContact O-CA 3.32Å; D242-E246 PolarHBondContact O-N 2.94Å; D242-T247 WeakPolarHBondContact CA-O 3.33Å; D242-T247 WeakPolarHBondContact CB-O 3.48Å; D242-T247 PolarHBondContact O-N 3.05Å; D242-E249 VanDerWaalsContact CG-N 3.27Å; D242-E249 WeakPolarHBondContact OD1-CA 3.45Å; D242-E249 PolarHBondContact OD1-N 3.45Å; D242-E249 VanDerWaalsContact OD1-N 3.15Å; D242-E249 PolarHBondContact OD2-N 2.76Å; D242-F250 PolarHBondContact OD1-N 3.14Å
243F96.9Very high96.2Very high15 Ų1529.9 Ų29.97%0.06617%0.169CC..Hα-helixtrans-67.9-51.9176.4-166.6-106.4000112L8 F19 F22 W179 M224 L239 L240 L241 T245 E246L8-F243 HydrophobicContact CD2-CD2 4.3Å; F19-F243 HydrophobicContact CB-CE2 4.39Å; F19-F243 HydrophobicContact CD2-CE2 4.04Å; F19-F243 HydrophobicContact CD2-CZ 4.22Å; F22-F243 HydrophobicContact CB-CD1 3.8Å; F22-F243 HydrophobicContact CB-CE1 3.8Å; F22-F243 HydrophobicContact CB-CG 4.18Å; F22-F243 HydrophobicContact CB-CZ 4.18Å; F22-F243 AromaticContact CD1-CE1 3.78Å; F22-F243 HydrophobicContact CD1-CE1 3.78Å; F22-F243 AromaticContact CD1-CZ 3.72Å; F22-F243 HydrophobicContact CD1-CZ 3.72Å; F22-F243 AromaticContact CD2-CD1 3.97Å; F22-F243 HydrophobicContact CD2-CD1 3.97Å; F22-F243 AromaticContact CD2-CE1 3.52Å; F22-F243 HydrophobicContact CD2-CE1 3.52Å; F22-F243 HydrophobicContact CD2-CZ 4.32Å; F22-F243 HydrophobicContact CE1-CE1 4.21Å; F22-F243 HydrophobicContact CE1-CZ 4.15Å; F22-F243 AromaticContact CE2-CE1 3.97Å; F22-F243 HydrophobicContact CE2-CE1 3.97Å; F22-F243 AromaticContact CG-CD1 3.88Å; F22-F243 HydrophobicContact CG-CD1 3.88Å; F22-F243 AromaticContact CG-CE1 3.4Å; F22-F243 HydrophobicContact CG-CE1 3.4Å; F22-F243 AromaticContact CG-CZ 3.8Å; F22-F243 HydrophobicContact CG-CZ 3.8Å; F22-F243 HydrophobicContact CZ-CE1 4.28Å; W179-F243 AromaticContact CH2-CD1 3.77Å; W179-F243 HydrophobicContact CH2-CD1 3.77Å; W179-F243 AromaticContact CH2-CE1 3.76Å; W179-F243 HydrophobicContact CH2-CE1 3.76Å; W179-F243 HydrophobicContact CZ2-CD1 4.29Å; W179-F243 AromaticContact CZ2-CE1 3.95Å; W179-F243 HydrophobicContact CZ2-CE1 3.95Å; M224-F243 HydrophobicContact CE-CD1 4.25Å; L239-F243 PolarHBondContact O-N 2.84Å; L239-F243 VanDerWaalsContact O-N 3.15Å; L240-F243 WeakPolarHBondContact O-CB 3.16Å; L240-F243 PolarHBondContact O-N 3.02Å; L241-F243 VanDerWaalsContact C-N 3.26Å; L241-F243 PolarHBondContact O-N 3.27Å; F243-T245 PolarHBondContact O-N 3.36Å; F243-T245 VanDerWaalsContact O-N 3.14Å; F243-E246 PolarHBondContact O-N 2.84Å; F243-E246 VanDerWaalsContact O-N 3.11Å
244L96.9Very high96.4Very high0 Ų027.4 Ų27.40%014%0.143CC..Hα-helixtrans-55.8-35.6179.2-74.1162.5000112.6W179 L182 M224 I226 L240 L241 L266 F281W179-L244 HydrophobicContact CH2-CD2 3.89Å; W179-L244 HydrophobicContact CZ2-CD2 4.39Å; W179-L244 HydrophobicContact CZ3-CD2 4.1Å; L182-L244 HydrophobicContact CD2-CB 4.32Å; L182-L244 WeakPolarHBondContact CD2-O 3.24Å; M224-L244 HydrophobicContact CE-CD2 4.45Å; M224-L244 HydrophobicContact CE-CG 4.24Å; M224-L244 HydrophobicContact SD-CD2 4.06Å; M224-L244 HydrophobicContact SD-CG 4.48Å; I226-L244 HydrophobicContact CG2-CD1 3.9Å; L240-L244 WeakPolarHBondContact O-CG 3.23Å; L240-L244 PolarHBondContact O-N 3.04Å; L241-L244 PolarHBondContact O-N 3.3Å; L244-L266 HydrophobicContact CD1-CD1 3.96Å; L244-L266 HydrophobicContact CD1-CD2 4.15Å; L244-L266 HydrophobicContact CD2-CD2 4.34Å; L244-F281 HydrophobicContact CD2-CD1 4.08Å; L244-F281 HydrophobicContact CD2-CD2 4.26Å; L244-F281 HydrophobicContact CD2-CE1 3.99Å; L244-F281 HydrophobicContact CD2-CE2 4.17Å; L244-F281 HydrophobicContact CD2-CG 4.19Å; L244-F281 HydrophobicContact CD2-CZ 4.01Å
245T95.6Very high96.4Very high0 Ų028 Ų280%015%0.149CC..THydrogen-bonded Turntrans-1000.6-175.9630000113.6L190 L241 F243 T247 F250 I262L190-T245 HydrophobicContact CD2-CG2 4.4Å; L241-T245 WeakPolarHBondContact O-CB 3.32Å; L241-T245 WeakPolarHBondContact O-CG2 3.45Å; L241-T245 PolarHBondContact O-N 3.05Å; L241-T245 PolarHBondContact O-OG1 3.33Å; F243-T245 PolarHBondContact O-N 3.36Å; F243-T245 VanDerWaalsContact O-N 3.14Å; T245-T247 PolarHBondContact O-N 3.15Å; T245-T247 PolarHBondContact O-OG1 3.48Å; T245-T247 WeakPolarHBondContact OG1-CB 3.48Å; T245-F250 HydrophobicContact CG2-CD1 3.97Å; T245-F250 HydrophobicContact CG2-CD2 3.77Å; T245-F250 HydrophobicContact CG2-CE1 4.01Å; T245-F250 HydrophobicContact CG2-CE2 3.82Å; T245-F250 HydrophobicContact CG2-CG 3.85Å; T245-F250 HydrophobicContact CG2-CZ 3.96Å; T245-F250 WeakPolarHBondContact OG1-CB 3.48Å; T245-F250 WeakPolarHBondContact OG1-CD2 3.01Å; T245-F250 WeakPolarHBondContact OG1-CG 3.41Å; T245-I262 HydrophobicContact CG2-CD1 4.3Å; T245-I262 HydrophobicContact CG2-CG2 4.19Å
246E94.6Very high96.3Very high15 Ų1528.3 Ų28.37%0.0715%0.154CC..THydrogen-bonded Turntrans42.340.1-170.4-66.1-61.8164.900112.9S7 L8 Y198 D242 F243S7-E246 CarbonylContact C-O 3.6Å; S7-E246 WeakPolarHBondContact CA-O 3.49Å; L8-E246 PolarHBondContact N-O 3.23Å; Y198-E246 HydrophobicContact CE1-CB 4.3Å; Y198-E246 HydrophobicContact CE1-CG 3.9Å; D242-E246 CarbonylContact O-C 3.54Å; D242-E246 VanDerWaalsContact O-CA 3.28Å; D242-E246 WeakPolarHBondContact O-CA 3.32Å; D242-E246 PolarHBondContact O-N 2.94Å; F243-E246 PolarHBondContact O-N 2.84Å; F243-E246 VanDerWaalsContact O-N 3.11Å
247T94.9Very high96.3Very high0 Ų032.3 Ų32.30%017%0.171CC..BIsolated β-bridgetrans-130.1128.2-172.6-60.50000111.2M5 K6 P191 D242 T245 E249 F250M5-T247 HydrophobicContact CB-CG2 3.87Å; M5-T247 HydrophobicContact CG-CG2 4.13Å; M5-T247 HydrophobicContact SD-CG2 4.31Å; K6-T247 CarbonylContact O-C 3.35Å; K6-T247 WeakPolarHBondContact O-CA 3.48Å; P191-T247 WeakPolarHBondContact CD-OG1 3.31Å; P191-T247 HydrophobicContact CG-CG2 3.97Å; P191-T247 WeakPolarHBondContact CG-OG1 3.49Å; D242-T247 WeakPolarHBondContact CA-O 3.33Å; D242-T247 WeakPolarHBondContact CB-O 3.48Å; D242-T247 PolarHBondContact O-N 3.05Å; T245-T247 PolarHBondContact O-N 3.15Å; T245-T247 PolarHBondContact O-OG1 3.48Å; T245-T247 WeakPolarHBondContact OG1-CB 3.48Å; T247-E249 PolarHBondContact O-N 3.42Å; T247-F250 HydrophobicContact CG2-CB 4.21Å; T247-F250 HydrophobicContact CG2-CD2 4.2Å
248C94.5Very high96.3Very high13 Ų1333 Ų339%0.08817%0.174CC..THydrogen-bonded Turntrans-65.6126.3173.3-71.80000111.5K6 N11 F250 T253K6-C248 PolarHBondContact O-N 3.07Å; N11-C248 VanDerWaalsContact CB-SG 3.54Å; C248-F250 VanDerWaalsContact C-N 3.26Å; C248-F250 PolarHBondContact O-N 3.32Å; C248-T253 PolarHBondContact O-OG1 2.93Å
249E95.3Very high96.2Very high71 Ų7133.9 Ų33.933%0.33218%0.177SC..THydrogen-bonded Turntrans52.246.1176.4-58.7-169.9103.900112R14 D242 T247 S251 K252 T253R14-E249 VanDerWaalsContact CZ-CG 3.45Å; D242-E249 VanDerWaalsContact CG-N 3.27Å; D242-E249 WeakPolarHBondContact OD1-CA 3.45Å; D242-E249 PolarHBondContact OD1-N 3.45Å; D242-E249 VanDerWaalsContact OD1-N 3.15Å; D242-E249 PolarHBondContact OD2-N 2.76Å; T247-E249 PolarHBondContact O-N 3.42Å; E249-S251 VanDerWaalsContact C-N 3.3Å; E249-S251 PolarHBondContact O-N 3.07Å; E249-K252 HydrophobicContact CB-CB 4.37Å; E249-K252 HydrophobicContact CB-CD 4.32Å; E249-K252 PolarHBondContact O-N 3.4Å; E249-K252 IonicContact OE1-NZ 2.72Å; E249-K252 PolarHBondContact OE1-NZ 3.04Å; E249-T253 HydrophobicContact CB-CG2 4.32Å; E249-T253 PolarHBondContact O-N 3.17Å; E249-T253 PolarHBondContact O-OG1 2.94Å
250F96.1Very high96.2Very high0 Ų038.8 Ų38.80%020%0.199CC..Hα-helixtrans-49.5-51-174.8173.2-102.3000111.5M5 L190 L241 D242 T245 T247 C248 K252 T253 A254 K259 I262M5-F250 HydrophobicContact SD-CD2 4.47Å; M5-F250 HydrophobicContact SD-CE2 4.49Å; L190-F250 HydrophobicContact CD2-CD2 4.42Å; L190-F250 HydrophobicContact CD2-CE2 4.06Å; L241-F250 HydrophobicContact CB-CD1 4.35Å; D242-F250 PolarHBondContact OD1-N 3.14Å; T245-F250 HydrophobicContact CG2-CD1 3.97Å; T245-F250 HydrophobicContact CG2-CD2 3.77Å; T245-F250 HydrophobicContact CG2-CE1 4.01Å; T245-F250 HydrophobicContact CG2-CE2 3.82Å; T245-F250 HydrophobicContact CG2-CG 3.85Å; T245-F250 HydrophobicContact CG2-CZ 3.96Å; T245-F250 WeakPolarHBondContact OG1-CB 3.48Å; T245-F250 WeakPolarHBondContact OG1-CD2 3.01Å; T245-F250 WeakPolarHBondContact OG1-CG 3.41Å; T247-F250 HydrophobicContact CG2-CB 4.21Å; T247-F250 HydrophobicContact CG2-CD2 4.2Å; C248-F250 VanDerWaalsContact C-N 3.26Å; C248-F250 PolarHBondContact O-N 3.32Å; F250-K252 PolarHBondContact O-N 2.92Å; F250-T253 PolarHBondContact O-N 3.29Å; F250-T253 VanDerWaalsContact O-N 3.17Å; F250-A254 HydrophobicContact CD2-CB 3.72Å; F250-A254 HydrophobicContact CE1-CB 4.33Å; F250-A254 HydrophobicContact CE2-CB 3.43Å; F250-A254 VanDerWaalsContact CE2-CB 3.43Å; F250-A254 HydrophobicContact CG-CB 4.28Å; F250-A254 HydrophobicContact CZ-CB 3.75Å; F250-A254 WeakPolarHBondContact O-CB 3.41Å; F250-A254 PolarHBondContact O-N 2.83Å; F250-K259 HydrophobicContact CE1-CB 4.35Å; F250-K259 HydrophobicContact CE1-CG 4.05Å; F250-K259 HydrophobicContact CZ-CB 4.39Å; F250-I262 HydrophobicContact CE1-CG2 4.49Å; F250-I262 HydrophobicContact CE2-CD1 3.95Å; F250-I262 HydrophobicContact CZ-CB 4.28Å; F250-I262 HydrophobicContact CZ-CD1 3.69Å; F250-I262 HydrophobicContact CZ-CG2 4.37Å
251S94.5Very high96.2Very high16 Ų1642.1 Ų42.111%0.11222%0.215CC..Hα-helixtrans-57.9-23.4-179.2-71.70000115.7E238 L241 E249 K259E238-S251 WeakPolarHBondContact OE2-CB 3.37Å; E238-S251 PolarHBondContact OE2-OG 3.46Å; L241-S251 WeakPolarHBondContact CD1-OG 3.24Å; E249-S251 VanDerWaalsContact C-N 3.3Å; E249-S251 PolarHBondContact O-N 3.07Å; S251-K259 PolarHBondContact O-NZ 3.39Å; S251-K259 VanDerWaalsContact O-NZ 3.1Å
252K94.3Very high96.2Very high146 Ų14642 Ų4264%0.63521%0.214SC*.Hα-helixtrans-97.8-29.3-178.7-59.5-178-170.3167.40112.5E249 F250E249-K252 HydrophobicContact CB-CB 4.37Å; E249-K252 HydrophobicContact CB-CD 4.32Å; E249-K252 PolarHBondContact O-N 3.4Å; E249-K252 IonicContact OE1-NZ 2.72Å; E249-K252 PolarHBondContact OE1-NZ 3.04Å; F250-K252 PolarHBondContact O-N 2.92Å
253T95.5Very high96.2Very high14 Ų1443.6 Ų43.69%0.08622%0.222CC..Hα-helixtrans-104.6-26.3-170.560.20000113.3C248 E249 F250C248-T253 PolarHBondContact O-OG1 2.93Å; E249-T253 HydrophobicContact CB-CG2 4.32Å; E249-T253 PolarHBondContact O-N 3.17Å; E249-T253 PolarHBondContact O-OG1 2.94Å; F250-T253 PolarHBondContact O-N 3.29Å; F250-T253 VanDerWaalsContact O-N 3.17Å
254A96.3Very high96.3Very high10 Ų1047.5 Ų47.58%0.08324%0.241CC..SBendtrans-65.8142.4-179.100000111.9M5 F250 K259M5-A254 HydrophobicContact SD-CB 3.9Å; F250-A254 HydrophobicContact CD2-CB 3.72Å; F250-A254 HydrophobicContact CE1-CB 4.33Å; F250-A254 HydrophobicContact CE2-CB 3.43Å; F250-A254 VanDerWaalsContact CE2-CB 3.43Å; F250-A254 HydrophobicContact CG-CB 4.28Å; F250-A254 HydrophobicContact CZ-CB 3.75Å; F250-A254 WeakPolarHBondContact O-CB 3.41Å; F250-A254 PolarHBondContact O-N 2.83Å; A254-K259 HydrophobicContact CB-CB 4.26Å
255P96.3Very high96.3Very high68 Ų6848 Ų4844%0.44224%0.243SC..  trans-52.6136.9166.8-25.234.5000110.6E257 L258 K259P255-E257 PolarHBondContact O-N 2.66Å; P255-E257 VanDerWaalsContact O-N 3.16Å; P255-L258 HydrophobicContact CB-CB 4.2Å; P255-L258 HydrophobicContact CG-CB 4.45Å; P255-L258 PolarHBondContact O-N 2.82Å; P255-K259 PolarHBondContact O-N 2.6Å
256P96.2Very high96.4Very high111 Ų11148 Ų4872%0.72124%0.243SC*.Hα-helixtrans-54.4-38.9-175.9-29.435.5000113.9K259 Q260P256-K259 PolarHBondContact O-N 3.22Å; P256-Q260 WeakPolarHBondContact O-CB 3.34Å; P256-Q260 PolarHBondContact O-N 2.9Å
257E97.1Very high96.5Very high134 Ų13453 Ų5363%0.62626%0.261SS*.Hα-helixtrans-65.2-45.7177.1-176.2177.7-17300112P255 K259 Q260 Q261P255-E257 PolarHBondContact O-N 2.66Å; P255-E257 VanDerWaalsContact O-N 3.16Å; E257-K259 VanDerWaalsContact C-N 3.35Å; E257-K259 PolarHBondContact O-N 3.3Å; E257-Q260 PolarHBondContact O-N 3.33Å; E257-Q261 WeakPolarHBondContact O-CB 3.35Å; E257-Q261 VanDerWaalsContact O-CG 3.26Å; E257-Q261 WeakPolarHBondContact O-CG 3.28Å; E257-Q261 PolarHBondContact O-N 2.84Å; E257-Q261 PolarHBondContact OE1-NE2 3.47Å
258L97Very high96.6Very high14 Ų1456.6 Ų56.67%0.07328%0.277CS..Hα-helixtrans-62-44.4176.6178.562.7000111.1M5 Y186 H189 P255 Q260 Q261 I262M5-L258 HydrophobicContact CE-CD2 3.83Å; M5-L258 HydrophobicContact SD-CD2 4.14Å; Y186-L258 HydrophobicContact CD1-CD1 3.93Å; H189-L258 HydrophobicContact CB-CD1 3.85Å; H189-L258 HydrophobicContact CB-CD2 4.15Å; P255-L258 HydrophobicContact CB-CB 4.2Å; P255-L258 HydrophobicContact CG-CB 4.45Å; P255-L258 PolarHBondContact O-N 2.82Å; L258-Q260 VanDerWaalsContact C-N 3.34Å; L258-Q260 PolarHBondContact O-N 2.96Å; L258-Q261 PolarHBondContact O-N 3.03Å; L258-I262 HydrophobicContact CD1-CD1 3.79Å; L258-I262 HydrophobicContact CD1-CG1 4.17Å; L258-I262 HydrophobicContact CG-CD1 4Å; L258-I262 PolarHBondContact O-N 2.91Å
259K97.1Very high96.7Very high67 Ų6761.6 Ų61.629%0.29131%0.309SS..Hα-helixtrans-57.6-49.2175.6-176-178.8-177.4177.60110.5F250 S251 A254 P255 P256 E257 Q261 I262 M263F250-K259 HydrophobicContact CE1-CB 4.35Å; F250-K259 HydrophobicContact CE1-CG 4.05Å; F250-K259 HydrophobicContact CZ-CB 4.39Å; S251-K259 PolarHBondContact O-NZ 3.39Å; S251-K259 VanDerWaalsContact O-NZ 3.1Å; A254-K259 HydrophobicContact CB-CB 4.26Å; P255-K259 PolarHBondContact O-N 2.6Å; P256-K259 PolarHBondContact O-N 3.22Å; E257-K259 VanDerWaalsContact C-N 3.35Å; E257-K259 PolarHBondContact O-N 3.3Å; K259-Q261 PolarHBondContact O-N 2.96Å; K259-I262 PolarHBondContact O-N 3.13Å; K259-M263 HydrophobicContact CG-CG 4.31Å; K259-M263 WeakPolarHBondContact O-CB 3.38Å; K259-M263 WeakPolarHBondContact O-CG 3.32Å; K259-M263 PolarHBondContact O-N 3.47Å
260Q97.7Very high96.7Very high117 Ų11763.2 Ų63.255%0.54732%0.317SS..Hα-helixtrans-58.9-48.5178.5-178.5-179.3-4.100111.6P256 E257 L258 I262 M263 E264P256-Q260 WeakPolarHBondContact O-CB 3.34Å; P256-Q260 PolarHBondContact O-N 2.9Å; E257-Q260 PolarHBondContact O-N 3.33Å; L258-Q260 VanDerWaalsContact C-N 3.34Å; L258-Q260 PolarHBondContact O-N 2.96Å; Q260-I262 PolarHBondContact O-N 2.93Å; Q260-M263 PolarHBondContact O-N 3.47Å; Q260-E264 HydrophobicContact CG-CG 4.47Å; Q260-E264 VanDerWaalsContact CG-OE1 3.31Å; Q260-E264 WeakPolarHBondContact CG-OE1 3.12Å; Q260-E264 PolarHBondContact NE2-OE1 3.48Å; Q260-E264 WeakPolarHBondContact O-CB 3.34Å; Q260-E264 WeakPolarHBondContact O-CG 3.29Å; Q260-E264 PolarHBondContact O-N 2.94Å
261Q98Very high96.8Very high70 Ų7063.2 Ų63.233%0.32732%0.317SS..Hα-helixtrans-61.6-44.4-178.8-72172.70.100112.6Y186 E257 L258 K259 E264 E265Y186-Q261 HydrophobicContact CE1-CB 3.85Å; Y186-Q261 PolarHBondContact OH-O 2.65Å; Y186-Q261 VanDerWaalsContact OH-O 3.12Å; E257-Q261 WeakPolarHBondContact O-CB 3.35Å; E257-Q261 VanDerWaalsContact O-CG 3.26Å; E257-Q261 WeakPolarHBondContact O-CG 3.28Å; E257-Q261 PolarHBondContact O-N 2.84Å; E257-Q261 PolarHBondContact OE1-NE2 3.47Å; L258-Q261 PolarHBondContact O-N 3.03Å; K259-Q261 PolarHBondContact O-N 2.96Å; Q261-E264 PolarHBondContact O-N 3.34Å; Q261-E265 WeakPolarHBondContact O-CB 3.44Å; Q261-E265 PolarHBondContact O-N 3.26Å
262I97.9Very high97Very high0 Ų062.8 Ų62.80%031%0.314CS..Hα-helixtrans-64.7-45.4176.6-73.9175.2000110.4L182 Y186 L190 T245 F250 L258 K259 Q260 E264 E265 L266L182-I262 HydrophobicContact CD1-CG2 4.27Å; Y186-I262 HydrophobicContact CD1-CD1 4.3Å; Y186-I262 HydrophobicContact CD1-CG1 3.75Å; Y186-I262 HydrophobicContact CD2-CG1 3.91Å; Y186-I262 HydrophobicContact CE1-CG1 4.06Å; Y186-I262 HydrophobicContact CE2-CG1 4.16Å; Y186-I262 HydrophobicContact CG-CD1 4.12Å; Y186-I262 HydrophobicContact CG-CG1 3.67Å; L190-I262 HydrophobicContact CD2-CD1 4.11Å; T245-I262 HydrophobicContact CG2-CD1 4.3Å; T245-I262 HydrophobicContact CG2-CG2 4.19Å; F250-I262 HydrophobicContact CE1-CG2 4.49Å; F250-I262 HydrophobicContact CE2-CD1 3.95Å; F250-I262 HydrophobicContact CZ-CB 4.28Å; F250-I262 HydrophobicContact CZ-CD1 3.69Å; F250-I262 HydrophobicContact CZ-CG2 4.37Å; L258-I262 HydrophobicContact CD1-CD1 3.79Å; L258-I262 HydrophobicContact CD1-CG1 4.17Å; L258-I262 HydrophobicContact CG-CD1 4Å; L258-I262 PolarHBondContact O-N 2.91Å; K259-I262 PolarHBondContact O-N 3.13Å; Q260-I262 PolarHBondContact O-N 2.93Å; I262-E264 VanDerWaalsContact C-N 3.32Å; I262-E264 PolarHBondContact O-N 3.27Å; I262-E265 PolarHBondContact O-N 3.48Å; I262-E265 VanDerWaalsContact O-N 3.13Å; I262-L266 HydrophobicContact CG2-CD1 4.01Å; I262-L266 HydrophobicContact CG2-CG 4.24Å; I262-L266 VanDerWaalsContact O-CG 3.3Å; I262-L266 WeakPolarHBondContact O-CG 3.46Å; I262-L266 PolarHBondContact O-N 3.48Å
263M97.9Very high97.1Very high34 Ų3460.3 Ų60.317%0.16730%0.304CS..Hα-helixtrans-60.8-40.4178.1-70.7-60.9-70.500112.4C229 F230 L241 K259 Q260 L266C229-M263 WeakPolarHBondContact O-CE 3.36Å; F230-M263 HydrophobicContact CD1-CE 3.36Å; F230-M263 HydrophobicContact CE1-CE 3.59Å; F230-M263 WeakPolarHBondContact CE1-O 3.31Å; F230-M263 HydrophobicContact CG-CE 4.16Å; L241-M263 HydrophobicContact CD1-SD 4.02Å; L241-M263 HydrophobicContact CD2-SD 3.56Å; L241-M263 VanDerWaalsContact CD2-SD 3.56Å; L241-M263 HydrophobicContact CG-SD 4.44Å; K259-M263 HydrophobicContact CG-CG 4.31Å; K259-M263 WeakPolarHBondContact O-CB 3.38Å; K259-M263 WeakPolarHBondContact O-CG 3.32Å; K259-M263 PolarHBondContact O-N 3.47Å; Q260-M263 PolarHBondContact O-N 3.47Å; M263-L266 HydrophobicContact SD-CD1 4.45Å
264E97.7Very high97.2Very high97 Ų9766 Ų6645%0.45333%0.33SS..Hα-helixtrans-65.4-42.3173.6-73.7173.9-168.200111.5Q260 Q261 I262 R267 K268Q260-E264 HydrophobicContact CG-CG 4.47Å; Q260-E264 VanDerWaalsContact CG-OE1 3.31Å; Q260-E264 WeakPolarHBondContact CG-OE1 3.12Å; Q260-E264 PolarHBondContact NE2-OE1 3.48Å; Q260-E264 WeakPolarHBondContact O-CB 3.34Å; Q260-E264 WeakPolarHBondContact O-CG 3.29Å; Q260-E264 PolarHBondContact O-N 2.94Å; Q261-E264 PolarHBondContact O-N 3.34Å; I262-E264 VanDerWaalsContact C-N 3.32Å; I262-E264 PolarHBondContact O-N 3.27Å; E264-R267 PolarHBondContact O-N 2.96Å; E264-K268 WeakPolarHBondContact O-CG 3.19Å
265E98Very high97.2Very high10 Ų1070.7 Ų70.75%0.04735%0.346CS..Hα-helixtrans-62.8-42.4178.3-157.778176.300112.7K185 Y186 Q261 I262 R267 K268 C271K185-E265 HydrophobicContact CD-CG 4.42Å; K185-E265 WeakPolarHBondContact CD-OE1 3.34Å; K185-E265 IonicContact NZ-OE1 2.88Å; K185-E265 PolarHBondContact NZ-OE1 2.96Å; K185-E265 IonicContact NZ-OE2 2.68Å; K185-E265 PolarHBondContact NZ-OE2 3.36Å; Y186-E265 HydrophobicContact CE2-CB 3.66Å; Y186-E265 HydrophobicContact CE2-CG 3.76Å; Y186-E265 PolarHBondContact OH-OE2 3.05Å; Q261-E265 WeakPolarHBondContact O-CB 3.44Å; Q261-E265 PolarHBondContact O-N 3.26Å; I262-E265 PolarHBondContact O-N 3.48Å; I262-E265 VanDerWaalsContact O-N 3.13Å; E265-R267 PolarHBondContact O-N 2.84Å; E265-K268 WeakPolarHBondContact O-CB 3.35Å; E265-K268 PolarHBondContact O-N 3.33Å; E265-K268 WeakPolarHBondContact OE2-CE 3.36Å; E265-K268 IonicContact OE2-NZ 2.73Å; E265-K268 PolarHBondContact OE2-NZ 3.34Å; E265-C271 WeakPolarHBondContact O-CB 3.3Å
266L98.1Very high97.1Very high0 Ų074.9 Ų74.90%036%0.364CS..THydrogen-bonded Turntrans-60.5-15.6-179.1-73.4174.7000113.2L182 I226 F230 L241 L244 I262 M263 S272 F281L182-L266 HydrophobicContact CD1-CD2 4.34Å; L182-L266 HydrophobicContact CD2-CD2 4.44Å; I226-L266 HydrophobicContact CD1-CB 3.93Å; I226-L266 HydrophobicContact CD1-CD2 4.31Å; I226-L266 HydrophobicContact CD1-CG 4.5Å; F230-L266 HydrophobicContact CZ-CB 4.04Å; L241-L266 HydrophobicContact CD2-CD1 3.94Å; L244-L266 HydrophobicContact CD1-CD1 3.96Å; L244-L266 HydrophobicContact CD1-CD2 4.15Å; L244-L266 HydrophobicContact CD2-CD2 4.34Å; I262-L266 HydrophobicContact CG2-CD1 4.01Å; I262-L266 HydrophobicContact CG2-CG 4.24Å; I262-L266 VanDerWaalsContact O-CG 3.3Å; I262-L266 WeakPolarHBondContact O-CG 3.46Å; I262-L266 PolarHBondContact O-N 3.48Å; M263-L266 HydrophobicContact SD-CD1 4.45Å; L266-S272 WeakPolarHBondContact O-CB 3.23Å; L266-S272 PolarHBondContact O-OG 3.04Å; L266-F281 HydrophobicContact CD2-CD2 3.94Å; L266-F281 HydrophobicContact CD2-CE2 3.86Å
267R96.5Very high97.1Very high121 Ų12173.2 Ų73.246%0.45737%0.367SS..THydrogen-bonded Turntrans-95.4-10.7173.2-68.9-169.1170.2-137.94.2114.2F230 E264 E265 E274F230-R267 VanDerWaalsContact CB-NH2 3.33Å; F230-R267 HydrophobicContact CD1-CG 4.33Å; F230-R267 HydrophobicContact CE1-CG 3.49Å; F230-R267 VanDerWaalsContact CE1-CG 3.49Å; F230-R267 VanDerWaalsContact CE1-NE 3.27Å; F230-R267 HydrophobicContact CE2-CG 4.17Å; F230-R267 VanDerWaalsContact CG-NH2 3.3Å; F230-R267 HydrophobicContact CZ-CG 3.39Å; E264-R267 PolarHBondContact O-N 2.96Å; E265-R267 PolarHBondContact O-N 2.84Å; R267-E274 IonicContact NH1-OE1 3.81Å
268K97.5Very high97.1Very high75 Ų7571.5 Ų71.533%0.32636%0.358SS..SBendtrans-76.4152.2-175.9-61.3-177.5-175.1162.60111.1E264 E265 E270 C271 S272E264-K268 WeakPolarHBondContact O-CG 3.19Å; E265-K268 WeakPolarHBondContact O-CB 3.35Å; E265-K268 PolarHBondContact O-N 3.33Å; E265-K268 WeakPolarHBondContact OE2-CE 3.36Å; E265-K268 IonicContact OE2-NZ 2.73Å; E265-K268 PolarHBondContact OE2-NZ 3.34Å; K268-E270 WeakPolarHBondContact CB-OE2 3.26Å; K268-E270 PolarHBondContact O-N 3.32Å; K268-C271 PolarHBondContact O-N 2.65Å; K268-S272 PolarHBondContact O-N 3.16Å
269P96.4Very high97.1Very high118 Ų11871.1 Ų71.177%0.76636%0.356SS*.THydrogen-bonded Turntrans-55.8-24.4-179.6-26.436000114.8C271 S272P269-C271 VanDerWaalsContact C-N 3.29Å; P269-C271 PolarHBondContact O-N 2.99Å; P269-S272 WeakPolarHBondContact CA-O 3.42Å
270E95.5Very high97.2Very high105 Ų10568.3 Ų68.349%0.49134%0.344SS..THydrogen-bonded Turntrans-73.8-18.9177.8-58.682.2178.500113.4T181 K268T181-E270 HydrophobicContact CG2-CB 3.87Å; T181-E270 PolarHBondContact OG1-O 3.36Å; T181-E270 VanDerWaalsContact OG1-O 3.12Å; K268-E270 WeakPolarHBondContact CB-OE2 3.26Å; K268-E270 PolarHBondContact O-N 3.32Å
271C97.1Very high97.3Very high0 Ų062.7 Ų62.70%032%0.318CS..THydrogen-bonded Turntrans-110.7-39.7177.2-73.60000112.5E265 K268 P269 F281 N282E265-C271 WeakPolarHBondContact O-CB 3.3Å; K268-C271 PolarHBondContact O-N 2.65Å; P269-C271 VanDerWaalsContact C-N 3.29Å; P269-C271 PolarHBondContact O-N 2.99Å; C271-F281 HydrophobicContact CB-CD2 4.16Å; C271-F281 HydrophobicContact CB-CE2 3.98Å; C271-F281 WeakPolarHBondContact O-CD2 2.88Å; C271-N282 WeakPolarHBondContact O-CB 3.21Å; C271-N282 PolarHBondContact O-N 2.97Å
272S98.3Very high97.3Very high7 Ų761.5 Ų61.55%0.04931%0.314CS..EExtended strand (participates in β ladder)trans-146.3161.7-168.6-55.80000112.5L266 K268 P269 L280 F281L266-S272 WeakPolarHBondContact O-CB 3.23Å; L266-S272 PolarHBondContact O-OG 3.04Å; K268-S272 PolarHBondContact O-N 3.16Å; P269-S272 WeakPolarHBondContact CA-O 3.42Å; S272-L280 CarbonylContact C-O 3.49Å; S272-L280 WeakPolarHBondContact CA-O 3.36Å; S272-L280 WeakPolarHBondContact CB-O 3.26Å; S272-F281 VanDerWaalsContact OG-CA 3.32Å; S272-F281 WeakPolarHBondContact OG-CA 3.33Å
273E97.6Very high97.3Very high94 Ų9461.5 Ų61.544%0.43931%0.314SS..EExtended strand (participates in β ladder)trans-114.1149.316564174.3-162.500111.3R275 L280E273-R275 IonicContact OE1-CZ 3.6Å; E273-R275 IonicContact OE1-NE 3.94Å; E273-R275 IonicContact OE1-NH1 2.53Å; E273-R275 PolarHBondContact OE1-NH1 3.28Å; E273-L280 HydrophobicContact CG-CB 3.97Å; E273-L280 PolarHBondContact N-O 3.32Å; E273-L280 PolarHBondContact O-N 3.43Å
274E96.6Very high97.3Very high135 Ų13561.8 Ų61.863%0.63132%0.316SS*.EExtended strand (participates in β ladder)trans-94.7120.2168.1-69.9-167.3176.500109.7R267 K278 V279R267-E274 IonicContact NH1-OE1 3.81Å; E274-K278 VanDerWaalsContact CA-O 3.3Å; E274-K278 WeakPolarHBondContact CA-O 3.39Å; E274-V279 HydrophobicContact CG-CG2 4.43Å
275R96.5Very high97.4Very high107 Ų10757.1 Ų57.140%0.40429%0.294SS..EExtended strand (participates in β ladder)trans-140.9126.2-178.3-169.6171.671.8-154.55.6110.3E273 G277 K278 L280E273-R275 IonicContact OE1-CZ 3.6Å; E273-R275 IonicContact OE1-NE 3.94Å; E273-R275 IonicContact OE1-NH1 2.53Å; E273-R275 PolarHBondContact OE1-NH1 3.28Å; R275-G277 PolarHBondContact O-N 3.16Å; R275-K278 PolarHBondContact N-O 3.18Å; R275-K278 WeakPolarHBondContact O-CB 3.4Å; R275-K278 PolarHBondContact O-N 3.04Å; R275-L280 HydrophobicContact CB-CD1 3.9Å
276D95Very high97.4Very high156 Ų15656.7 Ų56.783%0.83429%0.292SS*.THydrogen-bonded Turntrans51.637.8179.5-56-44.2000114.3K278D276-K278 VanDerWaalsContact C-N 3.26Å; D276-K278 PolarHBondContact O-N 2.84Å
277G94.6Very high97.4Very high76 Ų7656.7 Ų56.778%0.78429%0.292SS*.THydrogen-bonded Turntrans768.8-178.600000114.8R275R275-G277 PolarHBondContact O-N 3.16Å
278K97.6Very high97.6Very high98 Ų9850.9 Ų50.943%0.42627%0.27SS..EExtended strand (participates in β ladder)trans-105.8150.9174.9-61.9174.5163.8-133.90111.2D225 T227 E274 R275 D276 L280D225-K278 WeakPolarHBondContact OD2-CD 3.47Å; D225-K278 WeakPolarHBondContact OD2-CE 3.38Å; D225-K278 IonicContact OD2-NZ 3.36Å; D225-K278 PolarHBondContact OD2-NZ 3.31Å; T227-K278 VanDerWaalsContact OG1-CA 3.28Å; T227-K278 WeakPolarHBondContact OG1-CA 3.3Å; E274-K278 VanDerWaalsContact CA-O 3.3Å; E274-K278 WeakPolarHBondContact CA-O 3.39Å; R275-K278 PolarHBondContact N-O 3.18Å; R275-K278 WeakPolarHBondContact O-CB 3.4Å; R275-K278 PolarHBondContact O-N 3.04Å; D276-K278 VanDerWaalsContact C-N 3.26Å; D276-K278 PolarHBondContact O-N 2.84Å; K278-L280 HydrophobicContact CB-CD2 3.91Å; K278-L280 HydrophobicContact CB-CG 4.33Å; K278-L280 HydrophobicContact CD-CD2 4.39Å
279V98.3Very high97.6Very high7 Ų747.5 Ų47.54%0.04226%0.256CS..EExtended strand (participates in β ladder)trans-99.8111.1169-172.80000108.1I226 T227 F230 E274I226-V279 HydrophobicContact CD1-CG1 3.87Å; I226-V279 HydrophobicContact CG1-CB 4.04Å; I226-V279 HydrophobicContact CG1-CG1 3.75Å; I226-V279 WeakPolarHBondContact CG1-O 3.43Å; I226-V279 PolarHBondContact N-O 2.88Å; T227-V279 PolarHBondContact OG1-N 2.85Å; F230-V279 HydrophobicContact CD2-CB 4.42Å; F230-V279 HydrophobicContact CD2-CG2 4.06Å; F230-V279 HydrophobicContact CE2-CB 3.9Å; F230-V279 HydrophobicContact CE2-CG1 3.84Å; F230-V279 HydrophobicContact CE2-CG2 3.86Å; F230-V279 HydrophobicContact CZ-CG1 4.38Å; E274-V279 HydrophobicContact CG-CG2 4.43Å
280L98.6Very high97.7Very high7 Ų741.9 Ų41.94%0.03722%0.22CC..EExtended strand (participates in β ladder)trans-106.5103-175.7-57.1-175.1000109.3H223 M224 D225 S272 E273 R275 K278H223-L280 HydrophobicContact CB-CB 4.2Å; M224-L280 CarbonylContact O-C 3.47Å; D225-L280 HydrophobicContact CB-CD2 4.04Å; S272-L280 CarbonylContact C-O 3.49Å; S272-L280 WeakPolarHBondContact CA-O 3.36Å; S272-L280 WeakPolarHBondContact CB-O 3.26Å; E273-L280 HydrophobicContact CG-CB 3.97Å; E273-L280 PolarHBondContact N-O 3.32Å; E273-L280 PolarHBondContact O-N 3.43Å; R275-L280 HydrophobicContact CB-CD1 3.9Å; K278-L280 HydrophobicContact CB-CD2 3.91Å; K278-L280 HydrophobicContact CB-CG 4.33Å; K278-L280 HydrophobicContact CD-CD2 4.39Å
281F98.8Very high97.8Very high0 Ų039.4 Ų39.40%021%0.208CC..EExtended strand (participates in β ladder)trans-66.3133.6174.5-177.6-98000110.2W179 H223 M224 I226 L244 L266 C271 S272 N283W179-F281 AromaticContact CD1-CE1 3.83Å; W179-F281 AromaticContact CD2-CE1 3.69Å; W179-F281 HydrophobicContact CD2-CE1 3.69Å; W179-F281 HydrophobicContact CD2-CZ 4.03Å; W179-F281 AromaticContact CE2-CE1 3.57Å; W179-F281 HydrophobicContact CE3-CE1 4.3Å; W179-F281 HydrophobicContact CE3-CZ 4.32Å; W179-F281 AromaticContact CG-CE1 3.89Å; W179-F281 HydrophobicContact CG-CE1 3.89Å; W179-F281 HydrophobicContact CG-CZ 4.18Å; W179-F281 HydrophobicContact CZ2-CE1 4.09Å; W179-F281 AromaticContact NE1-CE1 3.65Å; H223-F281 CarbonylContact C-O 3.55Å; H223-F281 VanDerWaalsContact CA-O 3.24Å; H223-F281 WeakPolarHBondContact CA-O 3.24Å; M224-F281 HydrophobicContact CB-CB 4.25Å; M224-F281 HydrophobicContact CB-CD1 4.5Å; M224-F281 PolarHBondContact N-O 2.92Å; M224-F281 PolarHBondContact O-N 3.35Å; M224-F281 HydrophobicContact SD-CD1 4.47Å; I226-F281 HydrophobicContact CD1-CB 3.98Å; I226-F281 HydrophobicContact CD1-CD2 4.47Å; I226-F281 HydrophobicContact CG1-CB 4.04Å; I226-F281 HydrophobicContact CG2-CB 3.81Å; L244-F281 HydrophobicContact CD2-CD1 4.08Å; L244-F281 HydrophobicContact CD2-CD2 4.26Å; L244-F281 HydrophobicContact CD2-CE1 3.99Å; L244-F281 HydrophobicContact CD2-CE2 4.17Å; L244-F281 HydrophobicContact CD2-CG 4.19Å; L244-F281 HydrophobicContact CD2-CZ 4.01Å; L266-F281 HydrophobicContact CD2-CD2 3.94Å; L266-F281 HydrophobicContact CD2-CE2 3.86Å; C271-F281 HydrophobicContact CB-CD2 4.16Å; C271-F281 HydrophobicContact CB-CE2 3.98Å; C271-F281 WeakPolarHBondContact O-CD2 2.88Å; S272-F281 VanDerWaalsContact OG-CA 3.32Å; S272-F281 WeakPolarHBondContact OG-CA 3.33Å; F281-N283 PolarHBondContact O-N 3.17Å
282N98.6Very high97.7Very high44 Ų4443.2 Ų43.224%0.23523%0.232CC..EExtended strand (participates in β ladder)trans-69.699.7178175-4.5000109.2A176 G178 C271 N284A176-N282 PolarHBondContact O-ND2 3.17Å; G178-N282 PolarHBondContact N-O 2.58Å; C271-N282 WeakPolarHBondContact O-CB 3.21Å; C271-N282 PolarHBondContact O-N 2.97Å; N282-N284 VanDerWaalsContact OD1-CB 3.26Å; N282-N284 WeakPolarHBondContact OD1-CB 3.35Å; N282-N284 PolarHBondContact OD1-N 2.89Å; N282-N284 PolarHBondContact OD1-ND2 2.95Å; N282-N284 PolarHBondContact OD1-OD1 3Å
283N98.4Very high97.6Very high1 Ų145 Ų451%0.00524%0.242CC..  trans-101.126.1178.9-17455.2000111.1E28 W179 S222 M224 F281 L285E28-N283 PolarHBondContact OE2-ND2 3.31Å; W179-N283 PolarHBondContact NE1-OD1 3.34Å; S222-N283 VanDerWaalsContact CB-O 3.26Å; S222-N283 WeakPolarHBondContact CB-O 3.13Å; S222-N283 CarbonylContact O-C 3.57Å; S222-N283 WeakPolarHBondContact O-CA 3.19Å; S222-N283 PolarHBondContact O-N 3.13Å; S222-N283 PolarHBondContact OG-ND2 3.44Å; S222-N283 VanDerWaalsContact OG-ND2 3.13Å; M224-N283 HydrophobicContact CB-CB 4.19Å; F281-N283 PolarHBondContact O-N 3.17Å; N283-L285 WeakPolarHBondContact O-CD2 3.45Å; N283-L285 PolarHBondContact O-N 2.92Å
284N98.5Very high97.6Very high39 Ų3942.4 Ų42.421%0.20923%0.231CC..  trans-49.5134.3-178.8-74.5-3.8000110.7S174 S177 L220 P221 S222 N282S174-N284 VanDerWaalsContact CB-O 3.31Å; S174-N284 WeakPolarHBondContact CB-O 3.3Å; S174-N284 PolarHBondContact N-O 2.86Å; S177-N284 WeakPolarHBondContact CB-O 3.34Å; L220-N284 WeakPolarHBondContact O-CA 3.5Å; P221-N284 VanDerWaalsContact CA-OD1 3.29Å; P221-N284 WeakPolarHBondContact CA-OD1 3.18Å; S222-N284 PolarHBondContact N-OD1 2.92Å; S222-N284 PolarHBondContact O-N 2.8Å; S222-N284 PolarHBondContact O-OD1 3.31Å; N282-N284 VanDerWaalsContact OD1-CB 3.26Å; N282-N284 WeakPolarHBondContact OD1-CB 3.35Å; N282-N284 PolarHBondContact OD1-N 2.89Å; N282-N284 PolarHBondContact OD1-ND2 2.95Å; N282-N284 PolarHBondContact OD1-OD1 3Å
285L98.6Very high97.7Very high0 Ų037.3 Ų37.30%021%0.209CC..EExtended strand (participates in β ladder)trans-105.7160174.5-51.7-175.3000109.1C31 M32 Q143 I171 L172 V173 L220 N283C31-L285 VanDerWaalsContact SG-CD1 3.54Å; M32-L285 HydrophobicContact CE-CD1 3.52Å; M32-L285 HydrophobicContact CG-CD1 4.06Å; Q143-L285 VanDerWaalsContact NE2-CD2 3.33Å; I171-L285 HydrophobicContact CG2-CB 4.45Å; I171-L285 HydrophobicContact CG2-CD1 4.23Å; L172-L285 CarbonylContact O-C 3.51Å; L172-L285 WeakPolarHBondContact O-CA 3.37Å; V173-L285 HydrophobicContact CG1-CD2 4.01Å; L220-L285 HydrophobicContact CB-CB 4.09Å; L220-L285 PolarHBondContact N-O 2.92Å; L220-L285 PolarHBondContact O-N 3.18Å; N283-L285 WeakPolarHBondContact O-CD2 3.45Å; N283-L285 PolarHBondContact O-N 2.92Å
286S98.6Very high97.8Very high0 Ų033.2 Ų33.20%020%0.197CC..EExtended strand (participates in β ladder)trans-122.4143.2164.5-43.80000110.2I171 L172 S174 S201 Y218 E219I171-S286 WeakPolarHBondContact CA-O 3.49Å; L172-S286 PolarHBondContact N-O 3.34Å; L172-S286 PolarHBondContact O-N 3.5Å; S174-S286 VanDerWaalsContact CA-OG 3.32Å; S174-S286 WeakPolarHBondContact CA-OG 3.48Å; S174-S286 WeakPolarHBondContact CB-OG 3.26Å; S174-S286 PolarHBondContact OG-OG 2.94Å; S201-S286 VanDerWaalsContact CB-CB 3.44Å; S201-S286 VanDerWaalsContact CB-OG 3.23Å; S201-S286 WeakPolarHBondContact CB-OG 3.43Å; S201-S286 PolarHBondContact OG-OG 2.99Å; Y218-S286 CarbonylContact O-C 3.54Å; Y218-S286 VanDerWaalsContact O-CA 3.24Å; Y218-S286 WeakPolarHBondContact O-CA 3.49Å; E219-S286 WeakPolarHBondContact OE1-CB 3.42Å; E219-S286 PolarHBondContact OE1-OG 3.12Å
287V98.8Very high97.9Very high0 Ų025.5 Ų25.50%016%0.158CC..EExtended strand (participates in β ladder)trans-104.1124.9165.4-178.50000108.1F35 L169 I170 I171 L217 Y218 L220 V289F35-V287 HydrophobicContact CD1-CG2 3.99Å; F35-V287 HydrophobicContact CD2-CB 4.29Å; F35-V287 HydrophobicContact CD2-CG2 3.92Å; F35-V287 HydrophobicContact CE1-CB 4.43Å; F35-V287 HydrophobicContact CE1-CG1 3.84Å; F35-V287 HydrophobicContact CE1-CG2 4.14Å; F35-V287 HydrophobicContact CE2-CB 3.95Å; F35-V287 HydrophobicContact CE2-CG1 3.93Å; F35-V287 HydrophobicContact CE2-CG2 4.05Å; F35-V287 HydrophobicContact CG-CG2 3.9Å; F35-V287 HydrophobicContact CZ-CB 4.04Å; F35-V287 HydrophobicContact CZ-CG1 3.51Å; F35-V287 HydrophobicContact CZ-CG2 4.17Å; L169-V287 HydrophobicContact CD1-CG1 3.75Å; L169-V287 HydrophobicContact CD2-CG1 4.24Å; L169-V287 HydrophobicContact CG-CG1 3.76Å; I170-V287 CarbonylContact O-C 3.53Å; I170-V287 WeakPolarHBondContact O-CA 3.49Å; I171-V287 HydrophobicContact CD1-CG2 3.97Å; I171-V287 HydrophobicContact CG1-CG1 4.4Å; I171-V287 HydrophobicContact CG1-CG2 3.94Å; I171-V287 HydrophobicContact CG2-CG2 4.44Å; L217-V287 CarbonylContact C-O 3.51Å; L217-V287 WeakPolarHBondContact CA-O 3.49Å; Y218-V287 HydrophobicContact CD2-CB 4.45Å; Y218-V287 PolarHBondContact N-O 3.31Å; Y218-V287 PolarHBondContact O-N 3.05Å; L220-V287 HydrophobicContact CD1-CB 4.14Å; L220-V287 HydrophobicContact CD1-CG2 3.5Å; L220-V287 VanDerWaalsContact CD1-CG2 3.5Å; L220-V287 HydrophobicContact CD2-CG2 3.68Å; L220-V287 HydrophobicContact CG-CG2 4.27Å; V287-V289 HydrophobicContact CG1-CG2 4.2Å
288I98.8Very high98.2Very high0 Ų022.1 Ų22.10%012%0.116CC..EExtended strand (participates in β ladder)trans-109.4120.4174.3-55.9169.1000108.1L169 I170 L172 I204 E205 L208 H215 Q216 L217 I290L169-I288 CarbonylContact C-O 3.43Å; L169-I288 WeakPolarHBondContact CA-O 3.33Å; I170-I288 HydrophobicContact CB-CB 4.42Å; I170-I288 PolarHBondContact N-O 3.15Å; I170-I288 PolarHBondContact O-N 2.91Å; L172-I288 HydrophobicContact CD2-CD1 3.86Å; L172-I288 HydrophobicContact CD2-CG1 4.45Å; I204-I288 HydrophobicContact CB-CD1 3.67Å; I204-I288 HydrophobicContact CG2-CD1 3.49Å; I204-I288 VanDerWaalsContact CG2-CD1 3.49Å; E205-I288 HydrophobicContact CG-CD1 4.44Å; L208-I288 HydrophobicContact CD1-CG2 3.59Å; H215-I288 HydrophobicContact CB-CG2 4.03Å; Q216-I288 WeakPolarHBondContact O-CA 3.44Å; L217-I288 HydrophobicContact CD1-CD1 4.22Å; L217-I288 HydrophobicContact CD1-CG1 3.5Å; L217-I288 VanDerWaalsContact CD1-CG1 3.5Å; I288-I290 HydrophobicContact CG2-CG1 4.03Å
289V98.8Very high98.2Very high4 Ų416.7 Ų16.72%0.0249%0.094CC..EExtended strand (participates in β ladder)trans-105.9121.1175.7179.30000108.6V43 K167 L169 H215 Q216 Y218 V287V43-V289 HydrophobicContact CG1-CG1 3.7Å; V43-V289 HydrophobicContact CG1-CG2 3.97Å; V43-V289 HydrophobicContact CG2-CG2 4.01Å; K167-V289 HydrophobicContact CB-CG1 4.33Å; K167-V289 HydrophobicContact CD-CG1 4.02Å; K167-V289 HydrophobicContact CG-CG1 4.43Å; L169-V289 HydrophobicContact CD1-CG2 4.38Å; H215-V289 CarbonylContact C-O 3.55Å; H215-V289 WeakPolarHBondContact CA-O 3.36Å; H215-V289 WeakPolarHBondContact CB-O 3.31Å; Q216-V289 PolarHBondContact N-O 3.35Å; Q216-V289 PolarHBondContact O-N 3.12Å; Y218-V289 HydrophobicContact CD2-CG2 4.28Å; Y218-V289 HydrophobicContact CE2-CB 4.37Å; Y218-V289 HydrophobicContact CE2-CG2 3.74Å; V287-V289 HydrophobicContact CG1-CG2 4.2Å
290I98.8Very high98.2Very high0 Ų017.5 Ų17.50%010%0.098CC..EExtended strand (participates in β ladder)trans-110.6134-175.7-51.8163.6000109.2I155 L168 I170 L208 L213 H215 I288I155-I290 HydrophobicContact CG2-CD1 4.44Å; L168-I290 HydrophobicContact CB-CB 4.18Å; L168-I290 HydrophobicContact CD2-CD1 3.71Å; L168-I290 HydrophobicContact CG-CD1 4Å; L168-I290 PolarHBondContact N-O 2.97Å; L168-I290 VanDerWaalsContact N-O 3.07Å; L168-I290 PolarHBondContact O-N 3.4Å; I170-I290 HydrophobicContact CD1-CD1 3.64Å; I170-I290 HydrophobicContact CG1-CD1 4.29Å; L208-I290 HydrophobicContact CD1-CD1 3.84Å; L208-I290 HydrophobicContact CD1-CG1 3.9Å; L208-I290 HydrophobicContact CD2-CD1 3.6Å; L208-I290 HydrophobicContact CD2-CG1 4.2Å; L208-I290 HydrophobicContact CG-CD1 4.38Å; L213-I290 HydrophobicContact CB-CG2 4.3Å; H215-I290 HydrophobicContact CB-CG1 4.14Å; I288-I290 HydrophobicContact CG2-CG1 4.03Å
291E98Very high98.2Very high53 Ų5318.3 Ų18.325%0.24810%0.103CC..  trans-80.3154.7175.4-61.8-65159.800111.6H159 K167 K214H159-E291 PolarHBondContact CD2-O 2.68Å; H159-E291 PolarHBondContact NE2-O 2.88Å; K167-E291 IonicContact NZ-OE1 2.67Å; K167-E291 PolarHBondContact NZ-OE1 3.48Å; K167-E291 IonicContact NZ-OE2 3.26Å; K167-E291 PolarHBondContact NZ-OE2 3.4Å; K214-E291 HydrophobicContact CB-CB 4.19Å; K214-E291 HydrophobicContact CB-CG 4.23Å; K214-E291 HydrophobicContact CD-CG 3.95Å; K214-E291 HydrophobicContact CG-CB 4.45Å; K214-E291 HydrophobicContact CG-CG 3.93Å; K214-E291 PolarHBondContact O-N 2.73Å
292P93.4Very high98.1Very high79 Ų7920 Ų2051%0.51311%0.112SC..  trans-65.60178.628.3-33.8000113.7H159 L162 E163 A164 A166H159-P292 PolarHBondContact CE1-OXT 3.34Å; H159-P292 PolarHBondContact NE2-OXT 2.85Å; H159-P292 VanDerWaalsContact NE2-OXT 3.13Å; L162-P292 HydrophobicContact CB-CB 3.88Å; L162-P292 HydrophobicContact CD1-CB 4.33Å; E163-P292 VanDerWaalsContact O-CB 3.27Å; E163-P292 WeakPolarHBondContact O-CB 3.45Å; A164-P292 WeakPolarHBondContact O-CG 3.16Å; A166-P292 WeakPolarHBondContact O-CD 3.39Å

Retrieved 292 of 292 residues in 121.6 ms (Link to these results)