A0A093HN86_STRCA Loading...

Platelet glycoprotein 4

AlphaFold DB , UniProt , Accession A0A093HN86, Species STRCA (Struthio camelus australis), Gene n/a, Length 471 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M41.4Very low72.9Confident252 Ų25292.5 Ų92.5100%1.24154%0.542SS*.  087.30-75.3168.8170.600108.6
2G46.4Very low74.3Confident79 Ų7985.8 Ų85.881%0.81451%0.506SS*.  trans-90.6112.9-18000000110N4G2-N4 PolarHBondContact O-N 3.27Å; G2-N4 VanDerWaalsContact O-N 3.08Å
3C51.1Low75.6Confident117 Ų11779.5 Ų79.579%0.79147%0.47SS*.  trans-62.9111.6171.2-163.10000108.2R5C3-R5 PolarHBondContact O-N 3.43Å; C3-R5 VanDerWaalsContact O-N 3.09Å
4N75.9Confident76.8Confident104 Ų10480.8 Ų80.856%0.55647%0.472SS*.  trans-62.5113179.9-170.3-7.1000108G2 N6 C7 G8G2-N4 PolarHBondContact O-N 3.27Å; G2-N4 VanDerWaalsContact O-N 3.08Å; N4-N6 PolarHBondContact O-N 2.7Å; N4-C7 HydrophobicContact CB-CB 4.11Å; N4-C7 WeakPolarHBondContact O-CA 3.1Å; N4-C7 WeakPolarHBondContact O-CB 3.41Å; N4-C7 PolarHBondContact O-N 3.11Å; N4-G8 PolarHBondContact O-N 3.31Å
5R76.4Confident77.9Confident153 Ų15381.5 Ų81.558%0.57747%0.472SS*.Hα-helixtrans-48.9-36.4-173.7-172.1178.573.1-175.92.1113.4C3 C7 G8 L9C3-R5 PolarHBondContact O-N 3.43Å; C3-R5 VanDerWaalsContact O-N 3.09Å; R5-C7 VanDerWaalsContact C-N 3.33Å; R5-G8 PolarHBondContact O-N 3.48Å; R5-L9 WeakPolarHBondContact O-CG 3.13Å; R5-L9 PolarHBondContact O-N 2.97Å; R5-L9 VanDerWaalsContact O-N 3.11Å
6N80Confident78.8Confident35 Ų3576.4 Ų76.419%0.18744%0.443CS..Hα-helixtrans-66.3-34.5176.5-72.5-0.8000112.7N4 L10 Y462N4-N6 PolarHBondContact O-N 2.7Å; N6-L10 WeakPolarHBondContact O-CB 3.5Å; N6-L10 PolarHBondContact O-N 3Å; N6-L10 VanDerWaalsContact O-N 3.07Å; N6-Y462 HydrophobicContact CB-CE2 4.14Å
7C81.8Confident79.6Confident71 Ų7173.7 Ų73.748%0.4843%0.431SS..Hα-helixtrans-66.8-44.2175.1-154.70000110.3N4 R5 L9 L10 T11N4-C7 HydrophobicContact CB-CB 4.11Å; N4-C7 WeakPolarHBondContact O-CA 3.1Å; N4-C7 WeakPolarHBondContact O-CB 3.41Å; N4-C7 PolarHBondContact O-N 3.11Å; R5-C7 VanDerWaalsContact C-N 3.33Å; C7-L9 PolarHBondContact O-N 3.24Å; C7-L10 PolarHBondContact O-N 3.25Å; C7-T11 WeakPolarHBondContact O-CB 3.18Å; C7-T11 PolarHBondContact O-N 2.97Å; C7-T11 PolarHBondContact O-OG1 3.2Å
8G83.6Confident80.4Confident33 Ų3374.4 Ų74.434%0.3444%0.436SS..Hα-helixtrans-61.3-41.9175.700000113.7N4 R5 T11 G12N4-G8 PolarHBondContact O-N 3.31Å; R5-G8 PolarHBondContact O-N 3.48Å; G8-T11 PolarHBondContact O-N 3.37Å; G8-G12 PolarHBondContact O-N 3.43Å
9L87.5Confident81.1Confident25 Ų2573.6 Ų73.613%0.13143%0.43CS..Hα-helixtrans-65.8-40.3176.2-68.6172.3000112.1R5 C7 G12 A13 F458 Y462 C465R5-L9 WeakPolarHBondContact O-CG 3.13Å; R5-L9 PolarHBondContact O-N 2.97Å; R5-L9 VanDerWaalsContact O-N 3.11Å; C7-L9 PolarHBondContact O-N 3.24Å; L9-G12 PolarHBondContact O-N 3.12Å; L9-A13 PolarHBondContact O-N 3.13Å; L9-A13 VanDerWaalsContact O-N 3.09Å; L9-F458 HydrophobicContact CD2-CD1 3.76Å; L9-F458 HydrophobicContact CD2-CE1 4.19Å; L9-Y462 HydrophobicContact CB-CD2 4.25Å; L9-C465 HydrophobicContact CD1-CB 4.17Å
10L88.4Confident81.6Confident78 Ų7871.1 Ų71.141%0.40842%0.418SS..Hα-helixtrans-67.2-41.5176.9-16175.9000111.4N6 C7 G12 A13 I14 Y462N6-L10 WeakPolarHBondContact O-CB 3.5Å; N6-L10 PolarHBondContact O-N 3Å; N6-L10 VanDerWaalsContact O-N 3.07Å; C7-L10 PolarHBondContact O-N 3.25Å; L10-G12 VanDerWaalsContact C-N 3.33Å; L10-G12 PolarHBondContact O-N 2.89Å; L10-A13 PolarHBondContact O-N 3.28Å; L10-I14 HydrophobicContact CG-CD1 4.31Å; L10-I14 VanDerWaalsContact O-CG1 3.3Å; L10-I14 WeakPolarHBondContact O-CG1 3.3Å; L10-I14 PolarHBondContact O-N 3.45Å; L10-Y462 HydrophobicContact CD1-CE2 4.47Å
11T89.8Confident82.2Confident71 Ų7172.7 Ų72.744%0.43642%0.424SS..Hα-helixtrans-59.5-43.4174.2-57.50000111.4C7 G8 A13 I14 I15C7-T11 WeakPolarHBondContact O-CB 3.18Å; C7-T11 PolarHBondContact O-N 2.97Å; C7-T11 PolarHBondContact O-OG1 3.2Å; G8-T11 PolarHBondContact O-N 3.37Å; T11-A13 VanDerWaalsContact C-N 3.35Å; T11-A13 PolarHBondContact O-N 3.07Å; T11-I14 PolarHBondContact O-N 3.36Å; T11-I15 HydrophobicContact CG2-CD1 3.98Å; T11-I15 VanDerWaalsContact O-CG1 3.29Å; T11-I15 WeakPolarHBondContact O-CG1 3.43Å; T11-I15 PolarHBondContact O-N 3.21Å
12G89.4Confident84.5Confident11 Ų1166.2 Ų66.211%0.11339%0.388CS..Hα-helixtrans-61.2-40.9175.600000113.1G8 L9 L10 I15 G16G8-G12 PolarHBondContact O-N 3.43Å; L9-G12 PolarHBondContact O-N 3.12Å; L10-G12 VanDerWaalsContact C-N 3.33Å; L10-G12 PolarHBondContact O-N 2.89Å; G12-I15 PolarHBondContact O-N 3.33Å; G12-G16 PolarHBondContact O-N 2.89Å
13A91.2Very high86.6Confident4 Ų462.4 Ų62.43%0.03335%0.35CS..Hα-helixtrans-64.4-44.7174.200000111.7L9 L10 T11 I15 G16 A17 F455 F458 M459L9-A13 PolarHBondContact O-N 3.13Å; L9-A13 VanDerWaalsContact O-N 3.09Å; L10-A13 PolarHBondContact O-N 3.28Å; T11-A13 VanDerWaalsContact C-N 3.35Å; T11-A13 PolarHBondContact O-N 3.07Å; A13-I15 VanDerWaalsContact C-N 3.34Å; A13-I15 PolarHBondContact O-N 3.09Å; A13-G16 PolarHBondContact O-N 3.4Å; A13-A17 PolarHBondContact O-N 3.11Å; A13-F455 HydrophobicContact CB-CD2 4.23Å; A13-F455 WeakPolarHBondContact O-CD2 3.22Å; A13-F458 HydrophobicContact CB-CB 3.99Å; A13-M459 HydrophobicContact CB-CG 3.83Å; A13-M459 HydrophobicContact CB-SD 3.74Å
14I92.6Very high88.4Confident98 Ų9858.4 Ų58.450%0.50333%0.328SS..Hα-helixtrans-59.8-44.9177.5-68.3164.3000110.7L10 T11 G16 A17 V18L10-I14 HydrophobicContact CG-CD1 4.31Å; L10-I14 VanDerWaalsContact O-CG1 3.3Å; L10-I14 WeakPolarHBondContact O-CG1 3.3Å; L10-I14 PolarHBondContact O-N 3.45Å; T11-I14 PolarHBondContact O-N 3.36Å; I14-G16 VanDerWaalsContact C-N 3.34Å; I14-G16 PolarHBondContact O-N 3.02Å; I14-A17 PolarHBondContact O-N 2.87Å; I14-V18 HydrophobicContact CG2-CG2 4.31Å; I14-V18 WeakPolarHBondContact O-CB 3.39Å; I14-V18 VanDerWaalsContact O-CG2 3.29Å; I14-V18 WeakPolarHBondContact O-CG2 3.45Å; I14-V18 PolarHBondContact O-N 2.94Å
15I92.8Very high89.1Confident92 Ų9257.9 Ų57.947%0.47232%0.324SS..Hα-helixtrans-59.7-46.2176.5-68.1165.8000110.6T11 G12 A13 A17 V18 L19T11-I15 HydrophobicContact CG2-CD1 3.98Å; T11-I15 VanDerWaalsContact O-CG1 3.29Å; T11-I15 WeakPolarHBondContact O-CG1 3.43Å; T11-I15 PolarHBondContact O-N 3.21Å; G12-I15 PolarHBondContact O-N 3.33Å; A13-I15 VanDerWaalsContact C-N 3.34Å; A13-I15 PolarHBondContact O-N 3.09Å; I15-A17 PolarHBondContact O-N 3.32Å; I15-V18 PolarHBondContact O-N 3.46Å; I15-L19 HydrophobicContact CG2-CD1 4.07Å; I15-L19 HydrophobicContact CG2-CG 4.49Å; I15-L19 WeakPolarHBondContact O-CG 3.38Å; I15-L19 PolarHBondContact O-N 3.29Å
16G93.3Very high89.6Confident0 Ų051.9 Ų51.90%030%0.303CS..Hα-helixtrans-59-45.4176.300000112.9G12 A13 I14 L19 A20 G451G12-G16 PolarHBondContact O-N 2.89Å; A13-G16 PolarHBondContact O-N 3.4Å; I14-G16 VanDerWaalsContact C-N 3.34Å; I14-G16 PolarHBondContact O-N 3.02Å; G16-L19 PolarHBondContact O-N 3.27Å; G16-A20 PolarHBondContact O-N 2.92Å; G16-G451 CarbonylContact C-O 3.33Å; G16-G451 WeakPolarHBondContact CA-O 3.41Å; G16-G451 CarbonylContact O-C 3.53Å; G16-G451 VanDerWaalsContact O-CA 3.25Å; G16-G451 WeakPolarHBondContact O-CA 3.39Å; G16-G451 VanDerWaalsContact O-O 3.14Å
17A92.3Very high89.9Confident30 Ų3053.3 Ų53.325%0.24831%0.31CS..Hα-helixtrans-62.4-44.517700000112.1A13 I14 I15 L19 A20 I21 F455A13-A17 PolarHBondContact O-N 3.11Å; I14-A17 PolarHBondContact O-N 2.87Å; I15-A17 PolarHBondContact O-N 3.32Å; A17-L19 PolarHBondContact O-N 3.48Å; A17-A20 PolarHBondContact O-N 2.91Å; A17-I21 WeakPolarHBondContact O-CB 3.35Å; A17-I21 WeakPolarHBondContact O-CD1 3.22Å; A17-I21 WeakPolarHBondContact O-CG1 3.49Å; A17-I21 PolarHBondContact O-N 3.46Å; A17-F455 HydrophobicContact CB-CD2 3.81Å; A17-F455 HydrophobicContact CB-CE2 4.18Å
18V93.8Very high90.2Very high86 Ų8653.8 Ų53.852%0.52131%0.313SS..Hα-helixtrans-62.6-42.1177.6170.60000111.2I14 I15 I21 F22I14-V18 HydrophobicContact CG2-CG2 4.31Å; I14-V18 WeakPolarHBondContact O-CB 3.39Å; I14-V18 VanDerWaalsContact O-CG2 3.29Å; I14-V18 WeakPolarHBondContact O-CG2 3.45Å; I14-V18 PolarHBondContact O-N 2.94Å; I15-V18 PolarHBondContact O-N 3.46Å; V18-I21 PolarHBondContact O-N 3.45Å; V18-F22 VanDerWaalsContact O-CB 3.26Å; V18-F22 WeakPolarHBondContact O-CB 3.42Å; V18-F22 PolarHBondContact O-N 3.45Å
19L92.8Very high90.3Very high59 Ų5955.5 Ų55.531%0.30932%0.316SS..Hα-helixtrans-62.9-43176.4-72.8172000112.2I15 G16 A17 F22 G23 L447 L454I15-L19 HydrophobicContact CG2-CD1 4.07Å; I15-L19 HydrophobicContact CG2-CG 4.49Å; I15-L19 WeakPolarHBondContact O-CG 3.38Å; I15-L19 PolarHBondContact O-N 3.29Å; G16-L19 PolarHBondContact O-N 3.27Å; A17-L19 PolarHBondContact O-N 3.48Å; L19-F22 PolarHBondContact O-N 2.88Å; L19-G23 PolarHBondContact O-N 3.24Å; L19-L447 HydrophobicContact CD2-CD2 4.08Å; L19-L454 HydrophobicContact CD1-CD1 4.09Å
20A92.6Very high90.1Very high23 Ų2354.3 Ų54.319%0.1931%0.311CS..Hα-helixtrans-65.7-43.3177.300000111.9G16 A17 G23 G24G16-A20 PolarHBondContact O-N 2.92Å; A17-A20 PolarHBondContact O-N 2.91Å; A20-G23 PolarHBondContact O-N 2.75Å; A20-G24 PolarHBondContact O-N 3.08Å
21I92.5Very high89.8Confident106 Ų10654.1 Ų54.154%0.54431%0.31SS..Hα-helixtrans-61.8-45175.1-69.2165.4000110.4A17 V18 G24 I25A17-I21 WeakPolarHBondContact O-CB 3.35Å; A17-I21 WeakPolarHBondContact O-CD1 3.22Å; A17-I21 WeakPolarHBondContact O-CG1 3.49Å; A17-I21 PolarHBondContact O-N 3.46Å; V18-I21 PolarHBondContact O-N 3.45Å; I21-G24 PolarHBondContact O-N 3.02Å; I21-I25 HydrophobicContact CG2-CD1 3.76Å; I21-I25 HydrophobicContact CG2-CG1 4.39Å; I21-I25 WeakPolarHBondContact O-CG1 3.44Å; I21-I25 PolarHBondContact O-N 2.93Å
22F90.9Very high89.7Confident115 Ų11554.6 Ų54.650%0.50431%0.31SS..Hα-helixtrans-63.2-44178.4-174.2-107.6000111.8V18 L19 G24 I25 L26 L447V18-F22 VanDerWaalsContact O-CB 3.26Å; V18-F22 WeakPolarHBondContact O-CB 3.42Å; V18-F22 PolarHBondContact O-N 3.45Å; L19-F22 PolarHBondContact O-N 2.88Å; F22-G24 VanDerWaalsContact C-N 3.3Å; F22-G24 PolarHBondContact O-N 2.96Å; F22-I25 PolarHBondContact O-N 3.42Å; F22-L26 WeakPolarHBondContact O-CB 3.29Å; F22-L26 PolarHBondContact O-N 3.45Å; F22-L447 HydrophobicContact CD1-CD1 3.92Å; F22-L447 HydrophobicContact CE1-CD1 4.2Å
23G89.9Confident89.5Confident0 Ų059 Ų590%033%0.33CS..Hα-helixtrans-58.6-41.1172.600000112.5L19 A20 L26 I27L19-G23 PolarHBondContact O-N 3.24Å; A20-G23 PolarHBondContact O-N 2.75Å; G23-L26 PolarHBondContact O-N 3.09Å; G23-I27 PolarHBondContact O-N 3.37Å
24G89.1Confident89.1Confident33 Ų3359.8 Ų59.834%0.3433%0.333SS..Hα-helixtrans-64.5-42174.700000113.8A20 I21 F22 L26 I27 P28A20-G24 PolarHBondContact O-N 3.08Å; I21-G24 PolarHBondContact O-N 3.02Å; F22-G24 VanDerWaalsContact C-N 3.3Å; F22-G24 PolarHBondContact O-N 2.96Å; G24-L26 VanDerWaalsContact C-N 3.33Å; G24-I27 PolarHBondContact O-N 3.43Å; G24-P28 VanDerWaalsContact O-CD 3.22Å; G24-P28 WeakPolarHBondContact O-CD 3.29Å
25I89.6Confident88.9Confident92 Ų9257.8 Ų57.847%0.47232%0.324SS..Hα-helixtrans-67.7-34.4175.5-68.1168000111.3I21 F22 I27 P28 V29I21-I25 HydrophobicContact CG2-CD1 3.76Å; I21-I25 HydrophobicContact CG2-CG1 4.39Å; I21-I25 WeakPolarHBondContact O-CG1 3.44Å; I21-I25 PolarHBondContact O-N 2.93Å; F22-I25 PolarHBondContact O-N 3.42Å; I25-I27 PolarHBondContact O-N 3.43Å; I25-P28 WeakPolarHBondContact O-CD 3.49Å; I25-P28 WeakPolarHBondContact O-CG 3.3Å; I25-V29 HydrophobicContact CG2-CG2 4.04Å; I25-V29 WeakPolarHBondContact O-CG2 3.32Å; I25-V29 PolarHBondContact O-N 3.03Å
26L88.7Confident88.6Confident27 Ų2759.8 Ų59.814%0.14133%0.329CS..Hα-helixtrans-67.5-18.3-179.8-166.267.1000112.7F22 G23 G24 G30 L443 Q444 L447F22-L26 WeakPolarHBondContact O-CB 3.29Å; F22-L26 PolarHBondContact O-N 3.45Å; G23-L26 PolarHBondContact O-N 3.09Å; G24-L26 VanDerWaalsContact C-N 3.33Å; L26-G30 VanDerWaalsContact O-CA 3.28Å; L26-G30 WeakPolarHBondContact O-CA 3.25Å; L26-G30 PolarHBondContact O-N 3.23Å; L26-L443 HydrophobicContact CD2-CD2 4.02Å; L26-L443 HydrophobicContact CD2-CG 4.2Å; L26-Q444 HydrophobicContact CB-CG 4.12Å; L26-Q444 HydrophobicContact CD2-CG 4Å; L26-Q444 HydrophobicContact CG-CG 4.01Å; L26-Q444 PolarHBondContact O-NE2 2.88Å; L26-L447 HydrophobicContact CD2-CD1 4.02Å
27I85.1Confident88.3Confident65 Ų6561.8 Ų61.833%0.33335%0.345SS..Hα-helixtrans-61.7-68.8173.3-64169.1000110.4G23 G24 I25 V29 G30 D31 Q444 I448G23-I27 PolarHBondContact O-N 3.37Å; G24-I27 PolarHBondContact O-N 3.43Å; I25-I27 PolarHBondContact O-N 3.43Å; I27-V29 VanDerWaalsContact C-N 3.27Å; I27-V29 PolarHBondContact O-N 2.98Å; I27-G30 PolarHBondContact O-N 3.46Å; I27-D31 WeakPolarHBondContact O-CB 3.5Å; I27-D31 PolarHBondContact O-N 3.48Å; I27-Q444 HydrophobicContact CG1-CB 4.25Å; I27-Q444 HydrophobicContact CG1-CG 4.14Å; I27-I448 HydrophobicContact CD1-CD1 3.73Å
28P87.6Confident88.1Confident81 Ų8160.9 Ų60.953%0.52634%0.336SS..Hα-helixtrans-64.5-30.7-177.926.4-35.9000113.1G24 I25 N32G24-P28 VanDerWaalsContact O-CD 3.22Å; G24-P28 WeakPolarHBondContact O-CD 3.29Å; I25-P28 WeakPolarHBondContact O-CD 3.49Å; I25-P28 WeakPolarHBondContact O-CG 3.3Å; P28-N32 WeakPolarHBondContact O-CB 3.29Å; P28-N32 PolarHBondContact O-N 3.24Å
29V86.6Confident87.9Confident69 Ų6961.3 Ų61.342%0.41833%0.331SS..Hα-helixtrans-72.4-45.6177.5175.10000111.2I25 I27 N32 I33I25-V29 HydrophobicContact CG2-CG2 4.04Å; I25-V29 WeakPolarHBondContact O-CG2 3.32Å; I25-V29 PolarHBondContact O-N 3.03Å; I27-V29 VanDerWaalsContact C-N 3.27Å; I27-V29 PolarHBondContact O-N 2.98Å; V29-N32 PolarHBondContact O-N 3.46Å; V29-I33 HydrophobicContact CG1-CD1 3.96Å; V29-I33 VanDerWaalsContact O-CG1 3.31Å; V29-I33 WeakPolarHBondContact O-CG1 3.34Å; V29-I33 PolarHBondContact O-N 3.38Å
30G83.4Confident87.7Confident1 Ų165.9 Ų65.91%0.0135%0.349CS..Hα-helixtrans-62.6-45.8178.300000111.6L26 I27 N32 I33 I34L26-G30 VanDerWaalsContact O-CA 3.28Å; L26-G30 WeakPolarHBondContact O-CA 3.25Å; L26-G30 PolarHBondContact O-N 3.23Å; I27-G30 PolarHBondContact O-N 3.46Å; G30-N32 VanDerWaalsContact C-N 3.34Å; G30-N32 PolarHBondContact O-N 2.9Å; G30-I33 PolarHBondContact O-N 2.95Å; G30-I33 VanDerWaalsContact O-N 3.15Å; G30-I34 WeakPolarHBondContact O-CG1 3.48Å; G30-I34 PolarHBondContact O-N 2.87Å
31D82.3Confident87.5Confident74 Ų7467.5 Ų67.540%0.39635%0.354SS..Hα-helixtrans-59.4-44.7177-66.8-12.3000111.1I27 I33 I34 D35I27-D31 WeakPolarHBondContact O-CB 3.5Å; I27-D31 PolarHBondContact O-N 3.48Å; D31-I33 VanDerWaalsContact C-N 3.33Å; D31-I33 PolarHBondContact O-N 2.76Å; D31-I34 PolarHBondContact O-N 2.98Å; D31-D35 WeakPolarHBondContact O-CB 3.28Å; D31-D35 PolarHBondContact O-N 3.42Å
32N86.6Confident87.4Confident81 Ų8162.6 Ų62.643%0.43333%0.329SS..Hα-helixtrans-65.2-34.2177.1-167.49.1000113P28 V29 G30 K36P28-N32 WeakPolarHBondContact O-CB 3.29Å; P28-N32 PolarHBondContact O-N 3.24Å; V29-N32 PolarHBondContact O-N 3.46Å; G30-N32 VanDerWaalsContact C-N 3.34Å; G30-N32 PolarHBondContact O-N 2.9Å; N32-K36 WeakPolarHBondContact O-CB 3.29Å; N32-K36 VanDerWaalsContact O-CG 3.26Å; N32-K36 WeakPolarHBondContact O-CG 3.34Å; N32-K36 PolarHBondContact O-N 3.01Å; N32-K36 WeakPolarHBondContact OD1-CE 3.28Å
33I85.4Confident87.6Confident103 Ų10358 Ų5853%0.52831%0.31SS..Hα-helixtrans-68.4-46175.1-69.8167000110.5V29 G30 D31 K36 A37V29-I33 HydrophobicContact CG1-CD1 3.96Å; V29-I33 VanDerWaalsContact O-CG1 3.31Å; V29-I33 WeakPolarHBondContact O-CG1 3.34Å; V29-I33 PolarHBondContact O-N 3.38Å; G30-I33 PolarHBondContact O-N 2.95Å; G30-I33 VanDerWaalsContact O-N 3.15Å; D31-I33 VanDerWaalsContact C-N 3.33Å; D31-I33 PolarHBondContact O-N 2.76Å; I33-K36 PolarHBondContact O-N 3.47Å; I33-A37 WeakPolarHBondContact O-CB 3.26Å; I33-A37 PolarHBondContact O-N 3.24Å
34I83.9Confident87.9Confident20 Ų2058.1 Ų58.110%0.10331%0.311CS..Hα-helixtrans-60-50.8176.2-67.8165.8000109.2G30 D31 K36 A37 I38 V437 L440G30-I34 WeakPolarHBondContact O-CG1 3.48Å; G30-I34 PolarHBondContact O-N 2.87Å; D31-I34 PolarHBondContact O-N 2.98Å; I34-K36 VanDerWaalsContact C-N 3.29Å; I34-K36 PolarHBondContact O-N 3.23Å; I34-A37 WeakPolarHBondContact O-CB 3.32Å; I34-A37 PolarHBondContact O-N 2.95Å; I34-I38 HydrophobicContact CG2-CG1 3.99Å; I34-I38 VanDerWaalsContact O-CG1 3.32Å; I34-I38 WeakPolarHBondContact O-CG1 3.38Å; I34-I38 PolarHBondContact O-N 3.26Å; I34-V437 HydrophobicContact CD1-CB 4.5Å; I34-V437 HydrophobicContact CD1-CG1 4.35Å; I34-V437 HydrophobicContact CD1-CG2 4.27Å; I34-V437 HydrophobicContact CG2-CG2 3.9Å; I34-L440 HydrophobicContact CD1-CB 4.37Å; I34-L440 HydrophobicContact CD1-CD1 3.63Å; I34-L440 HydrophobicContact CG1-CD1 3.64Å
35D86.6Confident88.1Confident57 Ų5757.9 Ų57.931%0.30530%0.304SS..Hα-helixtrans-55.4-45.4-180-82.14.5000111.6D31 K39 F256D31-D35 WeakPolarHBondContact O-CB 3.28Å; D31-D35 PolarHBondContact O-N 3.42Å; D35-K39 VanDerWaalsContact O-CB 3.24Å; D35-K39 WeakPolarHBondContact O-CB 3.22Å; D35-K39 WeakPolarHBondContact O-CG 3.44Å; D35-K39 PolarHBondContact O-N 3.42Å; D35-F256 HydrophobicContact CB-CZ 4.27Å; D35-F256 WeakPolarHBondContact OD1-CE1 3.37Å
36K88.1Confident88.1Confident133 Ų13359.4 Ų59.458%0.57831%0.313SS*.Hα-helixtrans-64.4-40.6176.4-76.2175.9-178.4179.20112.7N32 I33 I34 K40N32-K36 WeakPolarHBondContact O-CB 3.29Å; N32-K36 VanDerWaalsContact O-CG 3.26Å; N32-K36 WeakPolarHBondContact O-CG 3.34Å; N32-K36 PolarHBondContact O-N 3.01Å; N32-K36 WeakPolarHBondContact OD1-CE 3.28Å; I33-K36 PolarHBondContact O-N 3.47Å; I34-K36 VanDerWaalsContact C-N 3.29Å; I34-K36 PolarHBondContact O-N 3.23Å; K36-K40 WeakPolarHBondContact O-CB 3.33Å; K36-K40 PolarHBondContact O-N 3.27Å; K36-K40 VanDerWaalsContact O-N 3.08Å
37A86.8Confident87.9Confident43 Ų4361.2 Ų61.236%0.35534%0.338SS..Hα-helixtrans-65.5-47.117800000111.2I33 I34 K40 D41I33-A37 WeakPolarHBondContact O-CB 3.26Å; I33-A37 PolarHBondContact O-N 3.24Å; I34-A37 WeakPolarHBondContact O-CB 3.32Å; I34-A37 PolarHBondContact O-N 2.95Å; A37-K40 WeakPolarHBondContact O-CB 3.34Å; A37-K40 PolarHBondContact O-N 2.93Å; A37-K40 VanDerWaalsContact O-N 3.14Å; A37-D41 PolarHBondContact O-N 3.4Å
38I88Confident88.1Confident11 Ų1159 Ų596%0.05633%0.327CS..Hα-helixtrans-62.4-47.9177.3-63.9-62.2000110.5I34 K40 D41 T42 P255 F256 I375 T376 V433I34-I38 HydrophobicContact CG2-CG1 3.99Å; I34-I38 VanDerWaalsContact O-CG1 3.32Å; I34-I38 WeakPolarHBondContact O-CG1 3.38Å; I34-I38 PolarHBondContact O-N 3.26Å; I38-K40 PolarHBondContact O-N 3.41Å; I38-K40 VanDerWaalsContact O-N 3.16Å; I38-D41 PolarHBondContact O-N 3.46Å; I38-T42 HydrophobicContact CG2-CG2 3.91Å; I38-T42 WeakPolarHBondContact O-CB 3.46Å; I38-T42 VanDerWaalsContact O-CG2 3.32Å; I38-T42 WeakPolarHBondContact O-CG2 3.22Å; I38-T42 PolarHBondContact O-N 3.27Å; I38-T42 PolarHBondContact O-OG1 3.41Å; I38-P255 HydrophobicContact CG2-CB 4.14Å; I38-F256 HydrophobicContact CB-CZ 4.1Å; I38-F256 HydrophobicContact CG2-CE1 4.27Å; I38-F256 HydrophobicContact CG2-CE2 4.47Å; I38-F256 HydrophobicContact CG2-CZ 3.87Å; I38-I375 HydrophobicContact CB-CG2 4.47Å; I38-I375 HydrophobicContact CD1-CG2 3.8Å; I38-I375 HydrophobicContact CG1-CG2 3.69Å; I38-I375 HydrophobicContact CG2-CG2 4.07Å; I38-T376 HydrophobicContact CD1-CG2 4.33Å; I38-V433 HydrophobicContact CD1-CG1 4.1Å
39K90.1Very high87.9Confident95 Ų9556.4 Ų56.441%0.41331%0.309SS..Hα-helixtrans-60.6-24.1176.5-72.2176.3-178.3173.40113D35 V43 I220 F256D35-K39 VanDerWaalsContact O-CB 3.24Å; D35-K39 WeakPolarHBondContact O-CB 3.22Å; D35-K39 WeakPolarHBondContact O-CG 3.44Å; D35-K39 PolarHBondContact O-N 3.42Å; K39-V43 VanDerWaalsContact O-CG2 3.26Å; K39-V43 WeakPolarHBondContact O-CG2 3.43Å; K39-I220 HydrophobicContact CB-CG1 4.41Å; K39-I220 HydrophobicContact CD-CG2 4.15Å; K39-I220 HydrophobicContact CG-CB 4.44Å; K39-I220 HydrophobicContact CG-CG1 4.24Å; K39-I220 HydrophobicContact CG-CG2 3.97Å; K39-I220 WeakPolarHBondContact O-CD1 3.25Å; K39-F256 HydrophobicContact CD-CE2 4.46Å; K39-F256 HydrophobicContact CG-CE2 3.89Å; K39-F256 HydrophobicContact CG-CZ 4.24Å
40K88.8Confident88Confident155 Ų15553.4 Ų53.467%0.67429%0.292SS*.Hα-helixtrans-82.3-45174-176.2-179.2174.8-176.40111.9K36 A37 I38 T42K36-K40 WeakPolarHBondContact O-CB 3.33Å; K36-K40 PolarHBondContact O-N 3.27Å; K36-K40 VanDerWaalsContact O-N 3.08Å; A37-K40 WeakPolarHBondContact O-CB 3.34Å; A37-K40 PolarHBondContact O-N 2.93Å; A37-K40 VanDerWaalsContact O-N 3.14Å; I38-K40 PolarHBondContact O-N 3.41Å; I38-K40 VanDerWaalsContact O-N 3.16Å; K40-T42 VanDerWaalsContact C-N 3.33Å; K40-T42 PolarHBondContact O-N 3.37Å
41D87.9Confident88.5Confident56 Ų5654.6 Ų54.630%0.29930%0.297SS..Hα-helixtrans-78.2-17.6-173.9-72.3-10.2000113.6A37 I38 I49 A50A37-D41 PolarHBondContact O-N 3.4Å; I38-D41 PolarHBondContact O-N 3.46Å; D41-I49 HydrophobicContact CB-CD1 4.5Å; D41-A50 PolarHBondContact O-N 2.89Å
42T90.9Very high88.7Confident4 Ų455.7 Ų55.73%0.02530%0.299CS..THydrogen-bonded Turntrans-90.4-8.5178.352.70000114.2I38 K40 A50 I220 T223 P255 T376 F378I38-T42 HydrophobicContact CG2-CG2 3.91Å; I38-T42 WeakPolarHBondContact O-CB 3.46Å; I38-T42 VanDerWaalsContact O-CG2 3.32Å; I38-T42 WeakPolarHBondContact O-CG2 3.22Å; I38-T42 PolarHBondContact O-N 3.27Å; I38-T42 PolarHBondContact O-OG1 3.41Å; K40-T42 VanDerWaalsContact C-N 3.33Å; K40-T42 PolarHBondContact O-N 3.37Å; T42-A50 VanDerWaalsContact O-CB 3.24Å; T42-A50 WeakPolarHBondContact O-CB 3.35Å; T42-I220 WeakPolarHBondContact OG1-CD1 3.03Å; T42-T223 VanDerWaalsContact O-CG2 3.31Å; T42-T223 WeakPolarHBondContact O-CG2 3.35Å; T42-P255 HydrophobicContact CG2-CB 4.42Å; T42-T376 HydrophobicContact CG2-CG2 4.4Å; T42-F378 HydrophobicContact CG2-CE1 4.33Å; T42-F378 HydrophobicContact CG2-CZ 4.16Å
43V95.3Very high88.7Confident18 Ų1854.3 Ų54.311%0.10929%0.292CS..SBendtrans-68135.3174.3172.60000110.2K39 S45 T48 T215 K217 I220K39-V43 VanDerWaalsContact O-CG2 3.26Å; K39-V43 WeakPolarHBondContact O-CG2 3.43Å; V43-S45 VanDerWaalsContact C-N 3.33Å; V43-S45 PolarHBondContact O-N 2.83Å; V43-T48 WeakPolarHBondContact O-CB 3.26Å; V43-T48 WeakPolarHBondContact O-CG2 3.25Å; V43-T48 PolarHBondContact O-OG1 3.42Å; V43-T215 WeakPolarHBondContact CA-O 3.28Å; V43-K217 HydrophobicContact CG1-CB 4.34Å; V43-K217 HydrophobicContact CG1-CG 3.44Å; V43-K217 VanDerWaalsContact CG1-CG 3.44Å; V43-I220 HydrophobicContact CG2-CD1 3.76Å
44I95.1Very high89Confident2 Ų250.1 Ų50.11%0.0127%0.269CS..  trans-77.586173.8-54.3170000108.7F51 W54 I111 V213 T215 T223 A224I44-F51 HydrophobicContact CG2-CD2 3.88Å; I44-W54 HydrophobicContact CD1-CG 4.39Å; I44-W54 HydrophobicContact CG2-CB 4.48Å; I44-W54 HydrophobicContact CG2-CD2 3.83Å; I44-W54 HydrophobicContact CG2-CE3 4.03Å; I44-W54 HydrophobicContact CG2-CG 4.04Å; I44-I111 HydrophobicContact CG2-CD1 4.33Å; I44-I111 HydrophobicContact CG2-CG2 4.12Å; I44-V213 HydrophobicContact CD1-CG2 4.4Å; I44-T215 PolarHBondContact N-O 2.77Å; I44-T215 WeakPolarHBondContact O-CB 3.29Å; I44-T215 WeakPolarHBondContact O-CG2 3.27Å; I44-T223 HydrophobicContact CD1-CG2 4.27Å; I44-T223 HydrophobicContact CG1-CG2 4.1Å; I44-A224 HydrophobicContact CD1-CB 4.01Å
45S93Very high89.4Confident28 Ų2851.7 Ų51.720%0.19628%0.277CS..SBendtrans-145148.1176.9-1740000110.5V43 G47 T48 F51 K217V43-S45 VanDerWaalsContact C-N 3.33Å; V43-S45 PolarHBondContact O-N 2.83Å; S45-G47 PolarHBondContact O-N 3.03Å; S45-T48 WeakPolarHBondContact O-CB 3.28Å; S45-T48 WeakPolarHBondContact O-CG2 3.32Å; S45-T48 PolarHBondContact O-N 3.36Å; S45-T48 VanDerWaalsContact O-N 3.09Å; S45-T48 PolarHBondContact O-OG1 2.96Å; S45-F51 WeakPolarHBondContact O-CB 3.35Å; S45-K217 VanDerWaalsContact OG-CE 3.28Å; S45-K217 WeakPolarHBondContact OG-CE 3.38Å; S45-K217 PolarHBondContact OG-NZ 3.49Å
46N89.1Confident89.4Confident125 Ų12551.5 Ų51.567%0.66828%0.278SS*.THydrogen-bonded Turntrans-51.5134.4179.4-164.7-0.2000111.9
47G84.7Confident89.1Confident64 Ų6447.6 Ų47.666%0.6627%0.267SS*.THydrogen-bonded Turntrans86.3-2.9-176.400000116.3S45S45-G47 PolarHBondContact O-N 3.03Å
48T88.9Confident88.6Confident18 Ų1847 Ų4711%0.1127%0.265CS..SBendtrans-91.5156.8174.464.40000112.1V43 S45 A50 F51 E52V43-T48 WeakPolarHBondContact O-CB 3.26Å; V43-T48 WeakPolarHBondContact O-CG2 3.25Å; V43-T48 PolarHBondContact O-OG1 3.42Å; S45-T48 WeakPolarHBondContact O-CB 3.28Å; S45-T48 WeakPolarHBondContact O-CG2 3.32Å; S45-T48 PolarHBondContact O-N 3.36Å; S45-T48 VanDerWaalsContact O-N 3.09Å; S45-T48 PolarHBondContact O-OG1 2.96Å; T48-A50 VanDerWaalsContact C-N 3.28Å; T48-A50 PolarHBondContact O-N 3.47Å; T48-F51 PolarHBondContact O-N 3.03Å; T48-F51 VanDerWaalsContact OG1-CB 3.26Å; T48-F51 WeakPolarHBondContact OG1-CB 3.28Å; T48-F51 PolarHBondContact OG1-N 3.04Å; T48-E52 PolarHBondContact O-N 2.65Å
49I84.5Confident88.6Confident28 Ų2847.6 Ų47.614%0.14427%0.27CS..Hα-helixtrans-64.3-37.1174.4-60.1172.1000110.6D41 N53 F378 K432D41-I49 HydrophobicContact CB-CD1 4.5Å; I49-N53 PolarHBondContact O-N 2.93Å; I49-N53 PolarHBondContact O-ND2 3.39Å; I49-N53 VanDerWaalsContact O-ND2 3.11Å; I49-F378 HydrophobicContact CG2-CE2 4.16Å; I49-K432 HydrophobicContact CD1-CB 4.49Å; I49-K432 HydrophobicContact CD1-CD 3.75Å
50A89.4Confident88.8Confident6 Ų646.3 Ų46.35%0.0527%0.27CS..Hα-helixtrans-61.6-44.5175.800000112.3D41 T42 T48 N53 W54 F378D41-A50 PolarHBondContact O-N 2.89Å; T42-A50 VanDerWaalsContact O-CB 3.24Å; T42-A50 WeakPolarHBondContact O-CB 3.35Å; T48-A50 VanDerWaalsContact C-N 3.28Å; T48-A50 PolarHBondContact O-N 3.47Å; A50-N53 PolarHBondContact O-N 3.19Å; A50-W54 WeakPolarHBondContact O-CA 3.31Å; A50-W54 WeakPolarHBondContact O-CB 3.35Å; A50-W54 PolarHBondContact O-N 2.8Å; A50-F378 HydrophobicContact CB-CE1 4.16Å; A50-F378 HydrophobicContact CB-CZ 3.91Å
51F92.3Very high89.1Confident26 Ų2639.2 Ų39.211%0.11424%0.239CC..Hα-helixtrans-65.8-42.6-179.5-175.4-93.4000112.9I44 S45 T48 N53 W54 L55 I111I44-F51 HydrophobicContact CG2-CD2 3.88Å; S45-F51 WeakPolarHBondContact O-CB 3.35Å; T48-F51 PolarHBondContact O-N 3.03Å; T48-F51 VanDerWaalsContact OG1-CB 3.26Å; T48-F51 WeakPolarHBondContact OG1-CB 3.28Å; T48-F51 PolarHBondContact OG1-N 3.04Å; F51-N53 PolarHBondContact O-N 3.43Å; F51-W54 HydrophobicContact CD2-CE3 4.05Å; F51-W54 HydrophobicContact CD2-CZ3 4.23Å; F51-W54 HydrophobicContact CE2-CE3 4.06Å; F51-W54 AromaticContact CE2-CZ3 3.79Å; F51-W54 HydrophobicContact CE2-CZ3 3.79Å; F51-W54 HydrophobicContact CZ-CZ3 4.41Å; F51-W54 PolarHBondContact O-N 3.04Å; F51-L55 HydrophobicContact CE1-CD2 4.38Å; F51-L55 WeakPolarHBondContact O-CB 3.49Å; F51-L55 PolarHBondContact O-N 3.3Å; F51-I111 HydrophobicContact CE2-CD1 3.95Å
52E87.4Confident89.6Confident97 Ų9739.6 Ų39.645%0.45324%0.237SC..Hα-helixtrans-59-48.5177.1-71.3-180-172.400111.7T48 L55 V56T48-E52 PolarHBondContact O-N 2.65Å; E52-L55 PolarHBondContact O-N 2.92Å; E52-V56 PolarHBondContact O-N 2.89Å
53N87.2Confident90Very high51 Ų5139.7 Ų39.727%0.27324%0.237SC..Hα-helixtrans-73-28.5178.7-71.4-47.4000112.9I49 A50 F51 V56I49-N53 PolarHBondContact O-N 2.93Å; I49-N53 PolarHBondContact O-ND2 3.39Å; I49-N53 VanDerWaalsContact O-ND2 3.11Å; A50-N53 PolarHBondContact O-N 3.19Å; F51-N53 PolarHBondContact O-N 3.43Å; N53-V56 CarbonylContact C-O 3.56Å; N53-V56 CarbonylContact O-C 3.53Å
54W92.1Very high90.2Very high15 Ų1540.6 Ų40.66%0.05724%0.24CC..Hα-helixtrans-70.5-40.9175.4171.690.5000110.9I44 A50 F51 K100 I103 I111 Y113I44-W54 HydrophobicContact CD1-CG 4.39Å; I44-W54 HydrophobicContact CG2-CB 4.48Å; I44-W54 HydrophobicContact CG2-CD2 3.83Å; I44-W54 HydrophobicContact CG2-CE3 4.03Å; I44-W54 HydrophobicContact CG2-CG 4.04Å; A50-W54 WeakPolarHBondContact O-CA 3.31Å; A50-W54 WeakPolarHBondContact O-CB 3.35Å; A50-W54 PolarHBondContact O-N 2.8Å; F51-W54 HydrophobicContact CD2-CE3 4.05Å; F51-W54 HydrophobicContact CD2-CZ3 4.23Å; F51-W54 HydrophobicContact CE2-CE3 4.06Å; F51-W54 AromaticContact CE2-CZ3 3.79Å; F51-W54 HydrophobicContact CE2-CZ3 3.79Å; F51-W54 HydrophobicContact CZ-CZ3 4.41Å; F51-W54 PolarHBondContact O-N 3.04Å; W54-K100 HydrophobicContact CD2-CD 3.95Å; W54-K100 HydrophobicContact CE3-CD 4.28Å; W54-K100 HydrophobicContact CH2-CD 4.2Å; W54-K100 HydrophobicContact CZ2-CD 3.88Å; W54-K100 HydrophobicContact CZ3-CD 4.4Å; W54-K100 VanDerWaalsContact NE1-NZ 3.17Å; W54-K100 VanDerWaalsContact O-CD 3.25Å; W54-K100 WeakPolarHBondContact O-CD 3.41Å; W54-K100 VanDerWaalsContact O-CE 3.23Å; W54-K100 WeakPolarHBondContact O-CE 3.4Å; W54-K100 PolarHBondContact O-NZ 3.21Å; W54-I103 HydrophobicContact CH2-CD1 4.16Å; W54-I103 HydrophobicContact CH2-CG1 4.11Å; W54-I103 HydrophobicContact CH2-CG2 4.15Å; W54-I103 HydrophobicContact CZ3-CD1 3.86Å; W54-I103 HydrophobicContact CZ3-CG1 4.33Å; W54-I103 HydrophobicContact CZ3-CG2 4.38Å; W54-I111 HydrophobicContact CH2-CD1 3.58Å; W54-I111 HydrophobicContact CH2-CG1 3.95Å; W54-I111 HydrophobicContact CH2-CG2 4.36Å; W54-I111 HydrophobicContact CZ2-CD1 4.27Å; W54-I111 HydrophobicContact CZ2-CG1 4.39Å; W54-I111 HydrophobicContact CZ2-CG2 4.01Å; W54-I111 HydrophobicContact CZ3-CD1 3.87Å; W54-Y113 HydrophobicContact CH2-CD1 4.19Å; W54-Y113 HydrophobicContact CH2-CG 4.22Å; W54-Y113 AromaticContact CZ2-CD1 3.36Å; W54-Y113 HydrophobicContact CZ2-CD1 3.36Å; W54-Y113 AromaticContact CZ2-CE1 3.85Å; W54-Y113 HydrophobicContact CZ2-CE1 3.85Å; W54-Y113 AromaticContact CZ2-CG 3.76Å; W54-Y113 HydrophobicContact CZ2-CG 3.76Å
55L91.3Very high90.4Very high53 Ų5340.5 Ų40.528%0.27724%0.24SC..Hα-helixtrans-64.9-51-177.8-179.862.3000111.8F51 E52 P99 K100 I103F51-L55 HydrophobicContact CE1-CD2 4.38Å; F51-L55 WeakPolarHBondContact O-CB 3.49Å; F51-L55 PolarHBondContact O-N 3.3Å; E52-L55 PolarHBondContact O-N 2.92Å; L55-P99 HydrophobicContact CD1-CB 4.04Å; L55-P99 HydrophobicContact CG-CB 4.11Å; L55-P99 WeakPolarHBondContact O-CA 3.25Å; L55-K100 HydrophobicContact CD1-CB 4.32Å; L55-K100 PolarHBondContact O-N 3.07Å; L55-I103 HydrophobicContact CD1-CD1 3.3Å
56V86.8Confident90.6Very high53 Ų5340.6 Ų40.632%0.32124%0.236SC..SBendtrans-134126172.5179.70000107.3E52 N53 G58 P99E52-V56 PolarHBondContact O-N 2.89Å; N53-V56 CarbonylContact C-O 3.56Å; N53-V56 CarbonylContact O-C 3.53Å; V56-G58 PolarHBondContact O-N 2.7Å; V56-P99 VanDerWaalsContact CG2-CA 3.48Å; V56-P99 HydrophobicContact CG2-CB 3.57Å; V56-P99 HydrophobicContact CG2-CG 4.48Å
57P81.9Confident91.1Very high52 Ų5234.6 Ų34.634%0.33820%0.204SC..  trans-53.5129.6174.5-2534.1000111S59 V61P57-S59 PolarHBondContact O-N 3.44Å; P57-S59 VanDerWaalsContact O-N 3.1Å; P57-V61 HydrophobicContact CB-CG2 4.44Å
58G75.8Confident91.8Very high30 Ų3031.6 Ų31.631%0.30917%0.173SC..SBendtrans-67.5-6.4175.700000114.1V56V56-G58 PolarHBondContact O-N 2.7Å
59S88.1Confident92.2Very high23 Ų2331.6 Ų31.616%0.16117%0.172CC..SBendtrans-110.6139.7179.3-51.40000110P57 V61 V420 I421P57-S59 PolarHBondContact O-N 3.44Å; P57-S59 VanDerWaalsContact O-N 3.1Å; S59-V61 PolarHBondContact O-N 3.29Å; S59-V420 WeakPolarHBondContact CB-O 3.26Å; S59-I421 VanDerWaalsContact OG-CA 3.25Å; S59-I421 WeakPolarHBondContact OG-CA 3.4Å; S59-I421 PolarHBondContact OG-N 2.96Å
60T94.1Very high92.9Very high69 Ų6930.4 Ų30.442%0.42317%0.166SC..  trans-68.4123.9169.5-51.10000109.3Y62 R94T60-Y62 HydrophobicContact CG2-CD2 4.27Å; T60-Y62 HydrophobicContact CG2-CE1 4.02Å; T60-Y62 HydrophobicContact CG2-CE2 3.6Å; T60-Y62 VanDerWaalsContact CG2-CZ 3.46Å; T60-R94 HydrophobicContact CG2-CG 3.74Å
61V96.2Very high93.3Very high5 Ų534.6 Ų34.63%0.0318%0.184CC..EExtended strand (participates in β ladder)trans-97.6126.4177.1-169.90000109P57 S59 V95 R96 F382 E417 A419P57-V61 HydrophobicContact CB-CG2 4.44Å; S59-V61 PolarHBondContact O-N 3.29Å; V61-V95 HydrophobicContact CB-CG2 4.12Å; V61-V95 HydrophobicContact CG1-CG2 3.75Å; V61-V95 PolarHBondContact O-N 2.91Å; V61-R96 HydrophobicContact CB-CB 4.21Å; V61-R96 HydrophobicContact CG2-CB 4.08Å; V61-F382 HydrophobicContact CG1-CZ 3.99Å; V61-E417 HydrophobicContact CG1-CG 3.68Å; V61-A419 HydrophobicContact CB-CB 4.41Å; V61-A419 HydrophobicContact CG1-CB 4.49Å; V61-A419 HydrophobicContact CG2-CB 3.99Å
62Y98.3Very high93.6Very high65 Ų6533.9 Ų33.926%0.25518%0.182SC..EExtended strand (participates in β ladder)trans-111.4139.8173.6-63.4-78.9000109.7T60 T92 Y93 R94 E122 M125 E417 S418T60-Y62 HydrophobicContact CG2-CD2 4.27Å; T60-Y62 HydrophobicContact CG2-CE1 4.02Å; T60-Y62 HydrophobicContact CG2-CE2 3.6Å; T60-Y62 VanDerWaalsContact CG2-CZ 3.46Å; Y62-T92 HydrophobicContact CD1-CG2 3.86Å; Y62-T92 HydrophobicContact CG-CG2 4.37Å; Y62-Y93 CarbonylContact C-O 3.4Å; Y62-Y93 WeakPolarHBondContact CA-O 3.41Å; Y62-R94 HydrophobicContact CD1-CB 4.32Å; Y62-R94 HydrophobicContact CE1-CB 4.26Å; Y62-R94 HydrophobicContact CE1-CG 4.32Å; Y62-E122 HydrophobicContact CD1-CG 4.39Å; Y62-E122 HydrophobicContact CE1-CG 4.09Å; Y62-M125 HydrophobicContact CD1-CE 4.28Å; Y62-M125 HydrophobicContact CD1-SD 4.21Å; Y62-M125 HydrophobicContact CD2-CE 4.38Å; Y62-M125 HydrophobicContact CE1-CE 4.15Å; Y62-M125 HydrophobicContact CE1-SD 3.66Å; Y62-M125 HydrophobicContact CE2-CE 4.26Å; Y62-M125 HydrophobicContact CG-CE 4.38Å; Y62-E417 CarbonylContact O-C 3.56Å; Y62-E417 VanDerWaalsContact O-CA 3.29Å; Y62-E417 WeakPolarHBondContact O-CA 3.35Å; Y62-S418 PolarHBondContact N-O 3.06Å; Y62-S418 PolarHBondContact O-N 3.06Å
63R98.6Very high94.1Very high6 Ų631 Ų312%0.02317%0.172CC..EExtended strand (participates in β ladder)trans-115.3115.1167.7-169.7-179.7-65.8158.62108.4F65 Y93 V95 Y203 L415 N416 E417R63-F65 HydrophobicContact CG-CE1 4Å; R63-F65 HydrophobicContact CG-CE2 4.18Å; R63-F65 HydrophobicContact CG-CZ 3.73Å; R63-Y93 PolarHBondContact N-O 3.4Å; R63-Y93 PolarHBondContact O-N 3.3Å; R63-V95 HydrophobicContact CB-CG1 3.93Å; R63-V95 HydrophobicContact CB-CG2 3.97Å; R63-Y203 VanDerWaalsContact NH1-CZ 3.27Å; R63-Y203 PolarHBondContact NH1-OH 3.05Å; R63-Y203 PolarHBondContact NH2-OH 3.08Å; R63-Y203 VanDerWaalsContact NH2-OH 3.11Å; R63-L415 HydrophobicContact CG-CB 4.4Å; R63-L415 HydrophobicContact CG-CD1 4.37Å; R63-N416 WeakPolarHBondContact CA-O 3.2Å; R63-E417 HydrophobicContact CG-CB 4.33Å; R63-E417 IonicContact CZ-OE2 3.31Å; R63-E417 IonicContact NE-OE2 3.45Å; R63-E417 PolarHBondContact NE-OE2 3.39Å; R63-E417 IonicContact NH2-OE2 2.73Å; R63-E417 PolarHBondContact NH2-OE2 2.86Å
64Q98.8Very high94.6Very high37 Ų3732.4 Ų32.417%0.17319%0.185CC..EExtended strand (participates in β ladder)trans-104.3137.7-180-58.3-178.4-65.100109.1W66 P90 Y91 T92 L415 N416Q64-W66 HydrophobicContact CB-CE3 4.32Å; Q64-W66 HydrophobicContact CB-CH2 3.67Å; Q64-W66 HydrophobicContact CB-CZ3 3.42Å; Q64-W66 VanDerWaalsContact CB-CZ3 3.42Å; Q64-W66 HydrophobicContact CG-CH2 4.5Å; Q64-P90 HydrophobicContact CB-CB 3.86Å; Q64-P90 HydrophobicContact CG-CB 4.28Å; Q64-Y91 WeakPolarHBondContact CA-O 3.19Å; Q64-T92 HydrophobicContact CG-CG2 4.03Å; Q64-T92 PolarHBondContact NE2-OG1 2.66Å; Q64-L415 CarbonylContact O-C 3.5Å; Q64-L415 WeakPolarHBondContact O-CA 3.46Å; Q64-L415 WeakPolarHBondContact O-CB 3.49Å; Q64-N416 HydrophobicContact CB-CB 4.47Å; Q64-N416 PolarHBondContact N-O 3.12Å; Q64-N416 PolarHBondContact O-N 3.05Å; Q64-N416 PolarHBondContact OE1-ND2 3.28Å
65F98.9Very high94.8Very high0 Ų036.1 Ų36.10%020%0.203CC..EExtended strand (participates in β ladder)trans-116.6136.8179.7-60.2-75.2000111.7R63 P90 Y91 Y93 L178 W179 F200 L413 L415R63-F65 HydrophobicContact CG-CE1 4Å; R63-F65 HydrophobicContact CG-CE2 4.18Å; R63-F65 HydrophobicContact CG-CZ 3.73Å; F65-P90 CarbonylContact O-C 3.25Å; F65-P90 WeakPolarHBondContact O-CA 3.36Å; F65-Y91 PolarHBondContact N-O 2.88Å; F65-Y91 PolarHBondContact O-N 3.21Å; F65-Y93 AromaticContact CD2-CD2 3.69Å; F65-Y93 HydrophobicContact CD2-CD2 3.69Å; F65-Y93 AromaticContact CD2-CE2 3.82Å; F65-Y93 HydrophobicContact CD2-CE2 3.82Å; F65-Y93 AromaticContact CE2-CD2 3.61Å; F65-Y93 HydrophobicContact CE2-CD2 3.61Å; F65-Y93 AromaticContact CE2-CE2 3.96Å; F65-Y93 HydrophobicContact CE2-CE2 3.96Å; F65-Y93 HydrophobicContact CE2-CG 4.37Å; F65-L178 HydrophobicContact CB-CD2 4.46Å; F65-L178 HydrophobicContact CD1-CD2 3.97Å; F65-L178 HydrophobicContact CD2-CD1 3.72Å; F65-L178 HydrophobicContact CD2-CD2 4.2Å; F65-L178 HydrophobicContact CE1-CD2 4.2Å; F65-L178 HydrophobicContact CE2-CD1 4.06Å; F65-L178 HydrophobicContact CE2-CD2 4.4Å; F65-L178 HydrophobicContact CG-CD1 4.16Å; F65-L178 HydrophobicContact CG-CD2 3.96Å; F65-L178 HydrophobicContact CZ-CD2 4.37Å; F65-W179 HydrophobicContact CE2-CH2 4.18Å; F65-W179 HydrophobicContact CE2-CZ2 4.11Å; F65-W179 HydrophobicContact CZ-CH2 4.2Å; F65-F200 HydrophobicContact CD1-CE2 4.06Å; F65-F200 HydrophobicContact CD1-CZ 4.4Å; F65-F200 HydrophobicContact CE1-CD2 4.16Å; F65-F200 HydrophobicContact CE1-CE1 4.45Å; F65-F200 AromaticContact CE1-CE2 3.3Å; F65-F200 HydrophobicContact CE1-CE2 3.3Å; F65-F200 AromaticContact CE1-CZ 3.5Å; F65-F200 HydrophobicContact CE1-CZ 3.5Å; F65-F200 HydrophobicContact CZ-CD2 4.24Å; F65-F200 AromaticContact CZ-CE2 3.82Å; F65-F200 HydrophobicContact CZ-CE2 3.82Å; F65-F200 HydrophobicContact CZ-CZ 4.19Å; F65-L413 HydrophobicContact CD1-CD1 4.19Å; F65-L415 HydrophobicContact CD1-CB 3.69Å; F65-L415 HydrophobicContact CE1-CB 3.85Å; F65-L415 HydrophobicContact CE1-CD2 4.07Å
66W98.8Very high95.1Very high29 Ų2933.9 Ų33.911%0.1119%0.192CC..EExtended strand (participates in β ladder)trans-118.9119.8166.4-71.7-104.7000108.1Q64 Q87 R88 P90 L413 W414 N416Q64-W66 HydrophobicContact CB-CE3 4.32Å; Q64-W66 HydrophobicContact CB-CH2 3.67Å; Q64-W66 HydrophobicContact CB-CZ3 3.42Å; Q64-W66 VanDerWaalsContact CB-CZ3 3.42Å; Q64-W66 HydrophobicContact CG-CH2 4.5Å; W66-Q87 HydrophobicContact CB-CB 4.45Å; W66-R88 WeakPolarHBondContact CA-O 3.24Å; W66-P90 HydrophobicContact CD2-CB 4.42Å; W66-P90 HydrophobicContact CH2-CB 3.84Å; W66-P90 HydrophobicContact CZ2-CB 3.59Å; W66-P90 HydrophobicContact CZ2-CG 4.01Å; W66-P90 HydrophobicContact CZ3-CB 4.35Å; W66-L413 CarbonylContact O-C 3.56Å; W66-L413 WeakPolarHBondContact O-CA 3.49Å; W66-L413 VanDerWaalsContact O-CB 3.26Å; W66-L413 WeakPolarHBondContact O-CB 3.31Å; W66-W414 HydrophobicContact CB-CD2 4.1Å; W66-W414 HydrophobicContact CB-CG 4.2Å; W66-W414 HydrophobicContact CB-CZ2 4.03Å; W66-W414 VanDerWaalsContact CB-NE1 3.28Å; W66-W414 HydrophobicContact CD2-CD2 4.3Å; W66-W414 AromaticContact CD2-CE2 3.67Å; W66-W414 AromaticContact CD2-CH2 3.57Å; W66-W414 HydrophobicContact CD2-CH2 3.57Å; W66-W414 AromaticContact CD2-CZ2 3.26Å; W66-W414 HydrophobicContact CD2-CZ2 3.26Å; W66-W414 HydrophobicContact CD2-CZ3 4.21Å; W66-W414 AromaticContact CE2-CH2 3.84Å; W66-W414 AromaticContact CE2-CZ2 3.66Å; W66-W414 AromaticContact CE3-CD2 3.93Å; W66-W414 HydrophobicContact CE3-CD2 3.93Å; W66-W414 AromaticContact CE3-CE2 3.76Å; W66-W414 AromaticContact CE3-CE3 3.79Å; W66-W414 HydrophobicContact CE3-CE3 3.79Å; W66-W414 AromaticContact CE3-CH2 3.31Å; W66-W414 HydrophobicContact CE3-CH2 3.31Å; W66-W414 AromaticContact CE3-CZ2 3.46Å; W66-W414 HydrophobicContact CE3-CZ2 3.46Å; W66-W414 VanDerWaalsContact CE3-CZ2 3.46Å; W66-W414 AromaticContact CE3-CZ3 3.5Å; W66-W414 HydrophobicContact CE3-CZ3 3.5Å; W66-W414 HydrophobicContact CG-CD2 4.41Å; W66-W414 AromaticContact CG-CE2 3.6Å; W66-W414 HydrophobicContact CG-CH2 4.32Å; W66-W414 AromaticContact CG-CZ2 3.54Å; W66-W414 HydrophobicContact CG-CZ2 3.54Å; W66-W414 AromaticContact CG-NE1 3.76Å; W66-W414 AromaticContact CH2-CH2 3.69Å; W66-W414 HydrophobicContact CH2-CH2 3.69Å; W66-W414 HydrophobicContact CH2-CZ2 4.35Å; W66-W414 HydrophobicContact CH2-CZ3 4.16Å; W66-W414 AromaticContact CZ2-CH2 3.91Å; W66-W414 HydrophobicContact CZ2-CH2 3.91Å; W66-W414 HydrophobicContact CZ2-CZ2 4.2Å; W66-W414 HydrophobicContact CZ3-CE3 4.15Å; W66-W414 AromaticContact CZ3-CH2 3.38Å; W66-W414 HydrophobicContact CZ3-CH2 3.38Å; W66-W414 HydrophobicContact CZ3-CZ2 4.01Å; W66-W414 AromaticContact CZ3-CZ3 3.47Å; W66-W414 HydrophobicContact CZ3-CZ3 3.47Å; W66-W414 VanDerWaalsContact CZ3-CZ3 3.47Å; W66-W414 PolarHBondContact N-O 3.23Å; W66-W414 PolarHBondContact O-N 2.88Å; W66-N416 HydrophobicContact CH2-CB 4.29Å; W66-N416 HydrophobicContact CZ3-CB 3.81Å
67I98.7Very high95.5Very high0 Ų033.9 Ų33.90%019%0.19CC..EExtended strand (participates in β ladder)trans-104.6136.4-175.8-57.3165.6000108.1D69 R88 Y91 I134 V174 I177 L413I67-D69 PolarHBondContact O-N 2.68Å; I67-R88 PolarHBondContact N-O 2.93Å; I67-R88 PolarHBondContact O-N 3.39Å; I67-Y91 HydrophobicContact CD1-CD2 4.47Å; I67-I134 HydrophobicContact CB-CD1 3.69Å; I67-I134 HydrophobicContact CD1-CD1 3.78Å; I67-I134 HydrophobicContact CG1-CD1 4.32Å; I67-I134 HydrophobicContact CG2-CD1 3.82Å; I67-I134 HydrophobicContact CG2-CG2 3.94Å; I67-V174 HydrophobicContact CD1-CB 4.35Å; I67-V174 HydrophobicContact CD1-CG1 4.02Å; I67-V174 HydrophobicContact CD1-CG2 4.06Å; I67-I177 HydrophobicContact CD1-CG2 3.87Å; I67-L413 HydrophobicContact CB-CB 4.35Å; I67-L413 HydrophobicContact CG1-CB 3.98Å; I67-L413 HydrophobicContact CG1-CD2 4.31Å
68F98.7Very high96.1Very high1 Ų136.9 Ų36.90%0.00420%0.203CC..EExtended strand (participates in β ladder)trans-82.1110.8178.7-68.5-70.5000110.5L85 Q87 H344 L359 Q387 P411 I412 W414F68-L85 HydrophobicContact CB-CB 4.28Å; F68-L85 HydrophobicContact CB-CD1 4.18Å; F68-L85 HydrophobicContact CB-CD2 4.36Å; F68-L85 HydrophobicContact CD1-CB 4.13Å; F68-L85 HydrophobicContact CD1-CD1 4.42Å; F68-L85 HydrophobicContact CG-CD1 4.32Å; F68-Q87 HydrophobicContact CD1-CB 4.18Å; F68-Q87 HydrophobicContact CE1-CB 4.06Å; F68-H344 AromaticContact CE1-CE1 3.71Å; F68-H344 AromaticContact CE1-NE2 3.97Å; F68-H344 AromaticContact CZ-NE2 3.96Å; F68-L359 HydrophobicContact CD1-CD2 4.17Å; F68-L359 HydrophobicContact CE1-CD2 3.54Å; F68-L359 HydrophobicContact CZ-CD2 3.81Å; F68-Q387 HydrophobicContact CE2-CG 4.34Å; F68-P411 HydrophobicContact CD2-CB 3.71Å; F68-P411 HydrophobicContact CD2-CG 4.14Å; F68-P411 HydrophobicContact CE2-CB 3.78Å; F68-P411 HydrophobicContact CE2-CG 4.42Å; F68-P411 HydrophobicContact CG-CG 4.48Å; F68-I412 PolarHBondContact N-O 3.07Å; F68-W414 AromaticContact CE2-CD1 3.96Å; F68-W414 AromaticContact CZ-CD1 3.7Å
69D98.6Very high96.9Very high17 Ų1739 Ų399%0.09121%0.213CC..EExtended strand (participates in β ladder)trans-89.7126.1178.1-162.86.8000110.6I67 Q71 L85 E86 R88 I134 T135I67-D69 PolarHBondContact O-N 2.68Å; D69-Q71 PolarHBondContact O-N 3.2Å; D69-Q71 PolarHBondContact O-NE2 3.3Å; D69-L85 WeakPolarHBondContact O-CA 3.11Å; D69-E86 WeakPolarHBondContact CB-O 3.21Å; D69-E86 PolarHBondContact N-O 3.29Å; D69-E86 PolarHBondContact O-N 3.38Å; D69-R88 HydrophobicContact CB-CG 4.16Å; D69-R88 VanDerWaalsContact OD2-CD 3.23Å; D69-R88 WeakPolarHBondContact OD2-CD 3.36Å; D69-R88 IonicContact OD2-NH1 3.76Å; D69-R88 PolarHBondContact OD2-NH1 3.42Å; D69-I134 HydrophobicContact CB-CG2 3.74Å; D69-I134 WeakPolarHBondContact OD1-CG2 3.27Å; D69-T135 WeakPolarHBondContact OD1-CA 3.47Å; D69-T135 WeakPolarHBondContact OD1-CB 3.28Å; D69-T135 PolarHBondContact OD1-N 3.36Å
70V98.7Very high97.2Very high3 Ų339.1 Ų39.12%0.01822%0.218CC..EExtended strand (participates in β ladder)trans-81.4118.9-177.9-177.70000110.7P73 V76 L85 T135 L169 F410V70-P73 HydrophobicContact CG1-CB 4.4Å; V70-V76 HydrophobicContact CG1-CG2 4.42Å; V70-L85 HydrophobicContact CG2-CD2 3.82Å; V70-T135 HydrophobicContact CB-CG2 4.1Å; V70-T135 WeakPolarHBondContact CG2-O 3.49Å; V70-T135 PolarHBondContact N-O 3.34Å; V70-L169 HydrophobicContact CB-CD1 4.49Å; V70-L169 HydrophobicContact CG1-CD1 3.94Å; V70-L169 HydrophobicContact CG2-CD2 4.29Å; V70-F410 HydrophobicContact CG2-CZ 3.72Å
71Q98.6Very high97.2Very high94 Ų9437.2 Ų37.244%0.43921%0.21SC..SBendtrans-88.2-22.4-175.1-56.9-51.9-5000113.7D69 P73 K84 E86D69-Q71 PolarHBondContact O-N 3.2Å; D69-Q71 PolarHBondContact O-NE2 3.3Å; Q71-P73 WeakPolarHBondContact O-CD 3.4Å; Q71-K84 HydrophobicContact CB-CB 4.24Å; Q71-K84 PolarHBondContact N-O 3.45Å; Q71-E86 HydrophobicContact CG-CB 3.95Å
72N98.1Very high97.2Very high11 Ų1140.9 Ų40.96%0.05923%0.226CC..  trans-121.450.5-17967.5-27.7000113.8S74 E75 V76 H82 K84N72-S74 VanDerWaalsContact C-N 3.3Å; N72-S74 PolarHBondContact O-N 2.91Å; N72-E75 HydrophobicContact CB-CB 4.24Å; N72-E75 HydrophobicContact CB-CG 4.33Å; N72-E75 PolarHBondContact ND2-OE2 3.44Å; N72-E75 VanDerWaalsContact ND2-OE2 3.09Å; N72-E75 PolarHBondContact O-N 2.68Å; N72-E75 VanDerWaalsContact O-N 3.09Å; N72-V76 WeakPolarHBondContact O-CG2 3.44Å; N72-V76 PolarHBondContact O-N 2.93Å; N72-V76 VanDerWaalsContact O-N 3.14Å; N72-H82 PolarHBondContact ND2-O 3.37Å; N72-K84 HydrophobicContact CB-CD 4.29Å; N72-K84 PolarHBondContact OD1-N 2.91Å
73P97.8Very high97.2Very high37 Ų3737.9 Ų37.924%0.2421%0.214CC..Hα-helixtrans-59.9-37.2-171.824.7-34.3000113.3V70 Q71 E75 V76 L77 T135 L169V70-P73 HydrophobicContact CG1-CB 4.4Å; Q71-P73 WeakPolarHBondContact O-CD 3.4Å; P73-E75 PolarHBondContact O-N 2.9Å; P73-V76 PolarHBondContact O-N 3.33Å; P73-L77 WeakPolarHBondContact O-CB 3.18Å; P73-L77 VanDerWaalsContact O-CG 3.24Å; P73-L77 WeakPolarHBondContact O-CG 3.27Å; P73-L77 PolarHBondContact O-N 2.93Å; P73-T135 HydrophobicContact CB-CG2 3.97Å; P73-T135 HydrophobicContact CG-CG2 4.31Å; P73-L169 HydrophobicContact CB-CD1 3.76Å
74S97.4Very high97.1Very high81 Ų8141.4 Ų41.457%0.56623%0.23SC*.Hα-helixtrans-63.6-38.8178.1-58.60000112.7N72 N78N72-S74 VanDerWaalsContact C-N 3.3Å; N72-S74 PolarHBondContact O-N 2.91Å; S74-N78 WeakPolarHBondContact O-CB 3.45Å; S74-N78 PolarHBondContact O-N 2.85Å; S74-N78 PolarHBondContact O-ND2 3.38Å; S74-N78 VanDerWaalsContact O-ND2 3.07Å
75E97.4Very high97.1Very high92 Ų9240.2 Ų40.243%0.4323%0.225SC..Hα-helixtrans-69.4-45.7177.7-63.9171.4-162.600110.2N72 P73 L77 N78 S79 G80 A81N72-E75 HydrophobicContact CB-CB 4.24Å; N72-E75 HydrophobicContact CB-CG 4.33Å; N72-E75 PolarHBondContact ND2-OE2 3.44Å; N72-E75 VanDerWaalsContact ND2-OE2 3.09Å; N72-E75 PolarHBondContact O-N 2.68Å; N72-E75 VanDerWaalsContact O-N 3.09Å; P73-E75 PolarHBondContact O-N 2.9Å; E75-L77 VanDerWaalsContact C-N 3.34Å; E75-L77 PolarHBondContact O-N 3.48Å; E75-N78 PolarHBondContact O-N 2.93Å; E75-S79 PolarHBondContact O-N 3.47Å; E75-S79 PolarHBondContact O-OG 3.27Å; E75-G80 PolarHBondContact O-N 3Å; E75-A81 HydrophobicContact CB-CB 3.78Å; E75-A81 PolarHBondContact O-N 3.06Å
76V96.4Very high97.1Very high6 Ų645.4 Ų45.44%0.03625%0.249CC..Hα-helixtrans-57.7-47.8176.9177.90000110.9V70 N72 P73 G80 P83 L169V70-V76 HydrophobicContact CG1-CG2 4.42Å; N72-V76 WeakPolarHBondContact O-CG2 3.44Å; N72-V76 PolarHBondContact O-N 2.93Å; N72-V76 VanDerWaalsContact O-N 3.14Å; P73-V76 PolarHBondContact O-N 3.33Å; V76-G80 VanDerWaalsContact O-CA 3.31Å; V76-G80 WeakPolarHBondContact O-CA 3.42Å; V76-G80 PolarHBondContact O-N 3.45Å; V76-P83 HydrophobicContact CG1-CG 4.4Å; V76-P83 HydrophobicContact CG2-CB 4.11Å; V76-P83 HydrophobicContact CG2-CG 4.11Å; V76-L169 HydrophobicContact CB-CD1 4.01Å; V76-L169 HydrophobicContact CG1-CD1 3.99Å
77L95.3Very high97Very high53 Ų5347 Ų4728%0.27726%0.258SS..Hα-helixtrans-73.8-34-176.4-68.2174.1000113.9P73 E75 V167 M168 L169 K403P73-L77 WeakPolarHBondContact O-CB 3.18Å; P73-L77 VanDerWaalsContact O-CG 3.24Å; P73-L77 WeakPolarHBondContact O-CG 3.27Å; P73-L77 PolarHBondContact O-N 2.93Å; E75-L77 VanDerWaalsContact C-N 3.34Å; E75-L77 PolarHBondContact O-N 3.48Å; L77-V167 HydrophobicContact CD1-CG2 4.18Å; L77-V167 HydrophobicContact CD2-CB 4.4Å; L77-V167 HydrophobicContact CD2-CG2 4.35Å; L77-M168 HydrophobicContact CD2-CB 3.91Å; L77-L169 HydrophobicContact CD1-CB 4.39Å; L77-L169 HydrophobicContact CD2-CB 4.26Å; L77-L169 HydrophobicContact CD2-CD1 4.48Å; L77-L169 HydrophobicContact CD2-CG 4.11Å; L77-L169 HydrophobicContact CG-CB 4.49Å; L77-L169 HydrophobicContact CG-CD1 4.21Å; L77-L169 HydrophobicContact CG-CG 4.35Å; L77-K403 WeakPolarHBondContact O-CG 3.49Å
78N94.5Very high97Very high115 Ų11550.6 Ų50.662%0.61527%0.271SS*.Hα-helixtrans-93.5-42-172.7-65.4-29.3000113.2S74 E75 K403S74-N78 WeakPolarHBondContact O-CB 3.45Å; S74-N78 PolarHBondContact O-N 2.85Å; S74-N78 PolarHBondContact O-ND2 3.38Å; S74-N78 VanDerWaalsContact O-ND2 3.07Å; E75-N78 PolarHBondContact O-N 2.93Å; N78-K403 WeakPolarHBondContact O-CE 3.42Å; N78-K403 PolarHBondContact O-NZ 3.07Å
79S93.6Very high97Very high75 Ų7551.4 Ų51.452%0.52428%0.28SS..Hα-helixtrans-110.7-11.6-175.559.40000113.8E75 A81E75-S79 PolarHBondContact O-N 3.47Å; E75-S79 PolarHBondContact O-OG 3.27Å; S79-A81 VanDerWaalsContact C-N 3.33Å
80G92.9Very high97Very high26 Ų2652.2 Ų52.227%0.26829%0.286SS..  trans73.428.3-173.600000112.4E75 V76E75-G80 PolarHBondContact O-N 3Å; V76-G80 VanDerWaalsContact O-CA 3.31Å; V76-G80 WeakPolarHBondContact O-CA 3.42Å; V76-G80 PolarHBondContact O-N 3.45Å
81A95.7Very high97Very high29 Ų2952 Ų5224%0.2429%0.285CS..PPolyproline II helixtrans-61.3158.7174.800000111.6E75 S79E75-A81 HydrophobicContact CB-CB 3.78Å; E75-A81 PolarHBondContact O-N 3.06Å; S79-A81 VanDerWaalsContact C-N 3.33Å
82H95.5Very high97Very high82 Ų8247.6 Ų47.638%0.3826%0.264SS..PPolyproline II helixtrans-64.3134.9174.4-67.1-171.3000110N72 K84 H354N72-H82 PolarHBondContact ND2-O 3.37Å; H82-K84 PolarHBondContact O-N 3.45Å; H82-H354 PolarHBondContact CE1-O 2.77Å; H82-H354 PolarHBondContact ND1-O 2.94Å
83P97.1Very high97Very high1 Ų147.2 Ų47.21%0.00626%0.262CS..PPolyproline II helixtrans-64.4127175.3-19.831.5000111.3V76 L85 V356 E357 Y408 F410V76-P83 HydrophobicContact CG1-CG 4.4Å; V76-P83 HydrophobicContact CG2-CB 4.11Å; V76-P83 HydrophobicContact CG2-CG 4.11Å; P83-L85 HydrophobicContact CB-CD2 3.98Å; P83-L85 HydrophobicContact CB-CG 4.44Å; P83-V356 HydrophobicContact CG-CG1 4.38Å; P83-E357 PolarHBondContact O-N 3.24Å; P83-Y408 HydrophobicContact CG-CE2 4.36Å; P83-F410 HydrophobicContact CB-CE2 3.83Å; P83-F410 HydrophobicContact CB-CZ 4.37Å; P83-F410 HydrophobicContact CG-CD2 4.06Å; P83-F410 HydrophobicContact CG-CE2 3.57Å
84K98.4Very high97Very high81 Ų8149.8 Ų49.835%0.35227%0.267SS..BIsolated β-bridgetrans-90.2118.7167.6-68.9173.1-179.2167.50108.5Q71 N72 H82 E357Q71-K84 HydrophobicContact CB-CB 4.24Å; Q71-K84 PolarHBondContact N-O 3.45Å; N72-K84 HydrophobicContact CB-CD 4.29Å; N72-K84 PolarHBondContact OD1-N 2.91Å; H82-K84 PolarHBondContact O-N 3.45Å; K84-E357 HydrophobicContact CB-CB 4.49Å; K84-E357 WeakPolarHBondContact CE-OE2 3.3Å; K84-E357 HydrophobicContact CG-CB 3.9Å; K84-E357 HydrophobicContact CG-CG 4.46Å
85L98.4Very high97Very high11 Ų1146 Ų466%0.05824%0.24CC..EExtended strand (participates in β ladder)trans-111.5138.5-172-55.8179.5000110.7F68 D69 V70 P83 V356 E357 L359 F410 P411F68-L85 HydrophobicContact CB-CB 4.28Å; F68-L85 HydrophobicContact CB-CD1 4.18Å; F68-L85 HydrophobicContact CB-CD2 4.36Å; F68-L85 HydrophobicContact CD1-CB 4.13Å; F68-L85 HydrophobicContact CD1-CD1 4.42Å; F68-L85 HydrophobicContact CG-CD1 4.32Å; D69-L85 WeakPolarHBondContact O-CA 3.11Å; V70-L85 HydrophobicContact CG2-CD2 3.82Å; P83-L85 HydrophobicContact CB-CD2 3.98Å; P83-L85 HydrophobicContact CB-CG 4.44Å; L85-V356 HydrophobicContact CD1-CB 4.04Å; L85-V356 HydrophobicContact CD1-CG1 4.23Å; L85-V356 HydrophobicContact CD1-CG2 4.36Å; L85-E357 PolarHBondContact N-O 3.01Å; L85-L359 HydrophobicContact CD1-CD2 4.43Å; L85-F410 HydrophobicContact CD2-CE1 4.47Å; L85-F410 HydrophobicContact CD2-CZ 4.02Å; L85-P411 HydrophobicContact CD1-CG 3.36Å
86E98.3Very high96.8Very high110 Ų11044.8 Ų44.851%0.51423%0.232SC..EExtended strand (participates in β ladder)trans-121.7127.8168-172.3178.4166.600108.5D69 Q71D69-E86 WeakPolarHBondContact CB-O 3.21Å; D69-E86 PolarHBondContact N-O 3.29Å; D69-E86 PolarHBondContact O-N 3.38Å; Q71-E86 HydrophobicContact CG-CB 3.95Å
87Q97.7Very high96.7Very high63 Ų6347.8 Ų47.829%0.29424%0.243SC..EExtended strand (participates in β ladder)trans-75.6133.7176.568.6167.715.600110.9W66 F68 H344W66-Q87 HydrophobicContact CB-CB 4.45Å; F68-Q87 HydrophobicContact CD1-CB 4.18Å; F68-Q87 HydrophobicContact CE1-CB 4.06Å; Q87-H344 PolarHBondContact OE1-NE2 2.83Å
88R98.3Very high96.7Very high74 Ų7448.5 Ų48.528%0.27925%0.247SC..EExtended strand (participates in β ladder)trans-119.9118.2174.4-67.2-173.463.5-165.6-6.2110.5W66 I67 D69 D132 T133 I134W66-R88 WeakPolarHBondContact CA-O 3.24Å; I67-R88 PolarHBondContact N-O 2.93Å; I67-R88 PolarHBondContact O-N 3.39Å; D69-R88 HydrophobicContact CB-CG 4.16Å; D69-R88 VanDerWaalsContact OD2-CD 3.23Å; D69-R88 WeakPolarHBondContact OD2-CD 3.36Å; D69-R88 IonicContact OD2-NH1 3.76Å; D69-R88 PolarHBondContact OD2-NH1 3.42Å; R88-D132 IonicContact NH2-OD2 3.05Å; R88-T133 PolarHBondContact NH1-O 3.09Å; R88-I134 HydrophobicContact CB-CD1 4.42Å
89G97.7Very high96.7Very high18 Ų1845.6 Ų45.619%0.18623%0.234CC..EExtended strand (participates in β ladder)trans169.9-176.3-178.900000112.4
90P98.5Very high96.8Very high34 Ų3442.9 Ų42.922%0.22121%0.213CC..EExtended strand (participates in β ladder)cis-76.2144.3-0.228.1-32.5000113Q64 F65 W66 S126 V127Q64-P90 HydrophobicContact CB-CB 3.86Å; Q64-P90 HydrophobicContact CG-CB 4.28Å; F65-P90 CarbonylContact O-C 3.25Å; F65-P90 WeakPolarHBondContact O-CA 3.36Å; W66-P90 HydrophobicContact CD2-CB 4.42Å; W66-P90 HydrophobicContact CH2-CB 3.84Å; W66-P90 HydrophobicContact CZ2-CB 3.59Å; W66-P90 HydrophobicContact CZ2-CG 4.01Å; W66-P90 HydrophobicContact CZ3-CB 4.35Å; P90-S126 CarbonylContact O-C 3.55Å; P90-S126 VanDerWaalsContact O-CA 3.27Å; P90-S126 WeakPolarHBondContact O-CA 3.07Å; P90-V127 PolarHBondContact O-N 2.95Å
91Y98.8Very high97Very high0 Ų044.8 Ų44.80%022%0.215CC..EExtended strand (participates in β ladder)trans-100.4111155.7-63.5-83000108.1Q64 F65 I67 F121 V127 T129 D132 I134 V174Q64-Y91 WeakPolarHBondContact CA-O 3.19Å; F65-Y91 PolarHBondContact N-O 2.88Å; F65-Y91 PolarHBondContact O-N 3.21Å; I67-Y91 HydrophobicContact CD1-CD2 4.47Å; Y91-F121 HydrophobicContact CD1-CE2 4.44Å; Y91-V127 HydrophobicContact CE1-CG1 4.29Å; Y91-V127 HydrophobicContact CE2-CG1 4.33Å; Y91-T129 WeakPolarHBondContact CE1-O 3.49Å; Y91-D132 HydrophobicContact CE1-CB 4.22Å; Y91-D132 WeakPolarHBondContact CE1-OD2 3.4Å; Y91-D132 VanDerWaalsContact OH-CB 3.29Å; Y91-D132 WeakPolarHBondContact OH-CB 3.21Å; Y91-D132 PolarHBondContact OH-OD2 3.02Å; Y91-I134 HydrophobicContact CE2-CD1 4.42Å; Y91-V174 HydrophobicContact CD1-CB 4.49Å; Y91-V174 HydrophobicContact CD1-CG1 3.95Å; Y91-V174 HydrophobicContact CD1-CG2 4.1Å; Y91-V174 HydrophobicContact CD2-CG1 4.03Å; Y91-V174 HydrophobicContact CD2-CG2 4.02Å; Y91-V174 HydrophobicContact CE1-CB 4.47Å; Y91-V174 HydrophobicContact CE1-CG1 4.4Å; Y91-V174 HydrophobicContact CE1-CG2 3.7Å; Y91-V174 HydrophobicContact CE2-CG1 4.46Å; Y91-V174 HydrophobicContact CE2-CG2 3.59Å; Y91-V174 HydrophobicContact CG-CG1 3.76Å; Y91-V174 HydrophobicContact CG-CG2 4.26Å; Y91-V174 VanDerWaalsContact CZ-CG2 3.43Å
92T98.9Very high97Very high0 Ų048.9 Ų48.90%023%0.232CC..EExtended strand (participates in β ladder)trans-99.4131.9-166.4-60.50000111.4Y62 Q64 F121 E122 M125 S126Y62-T92 HydrophobicContact CD1-CG2 3.86Å; Y62-T92 HydrophobicContact CG-CG2 4.37Å; Q64-T92 HydrophobicContact CG-CG2 4.03Å; Q64-T92 PolarHBondContact NE2-OG1 2.66Å; T92-F121 VanDerWaalsContact O-CD2 3.32Å; T92-F121 WeakPolarHBondContact O-CD2 3.44Å; T92-E122 HydrophobicContact CG2-CB 4.14Å; T92-E122 PolarHBondContact O-N 2.81Å; T92-M125 WeakPolarHBondContact CB-O 3.31Å; T92-M125 HydrophobicContact CG2-CB 3.83Å; T92-M125 HydrophobicContact CG2-CE 4.27Å; T92-M125 HydrophobicContact CG2-SD 4.37Å; T92-M125 PolarHBondContact OG1-O 2.93Å; T92-S126 PolarHBondContact N-OG 3.19Å
93Y98.7Very high97.1Very high3 Ų347.9 Ų47.91%0.01223%0.229CC..EExtended strand (participates in β ladder)trans-126.6135173.6-66.2-103.9000110.5Y62 R63 F65 A119 H120 F121 E130 L178 W179Y62-Y93 CarbonylContact C-O 3.4Å; Y62-Y93 WeakPolarHBondContact CA-O 3.41Å; R63-Y93 PolarHBondContact N-O 3.4Å; R63-Y93 PolarHBondContact O-N 3.3Å; F65-Y93 AromaticContact CD2-CD2 3.69Å; F65-Y93 HydrophobicContact CD2-CD2 3.69Å; F65-Y93 AromaticContact CD2-CE2 3.82Å; F65-Y93 HydrophobicContact CD2-CE2 3.82Å; F65-Y93 AromaticContact CE2-CD2 3.61Å; F65-Y93 HydrophobicContact CE2-CD2 3.61Å; F65-Y93 AromaticContact CE2-CE2 3.96Å; F65-Y93 HydrophobicContact CE2-CE2 3.96Å; F65-Y93 HydrophobicContact CE2-CG 4.37Å; Y93-A119 HydrophobicContact CD1-CB 3.92Å; Y93-A119 HydrophobicContact CG-CB 4.34Å; Y93-H120 CarbonylContact C-O 3.53Å; Y93-H120 WeakPolarHBondContact CA-O 3.5Å; Y93-F121 HydrophobicContact CD1-CB 3.9Å; Y93-F121 HydrophobicContact CD1-CD2 4.2Å; Y93-F121 HydrophobicContact CD2-CD2 4.18Å; Y93-F121 HydrophobicContact CE1-CB 3.66Å; Y93-F121 AromaticContact CE1-CD2 3.79Å; Y93-F121 HydrophobicContact CE1-CD2 3.79Å; Y93-F121 HydrophobicContact CE1-CG 4.16Å; Y93-F121 AromaticContact CE2-CD2 3.75Å; Y93-F121 HydrophobicContact CE2-CD2 3.75Å; Y93-F121 HydrophobicContact CE2-CE2 4.28Å; Y93-F121 HydrophobicContact CG-CD2 4.39Å; Y93-F121 AromaticContact CZ-CD2 3.55Å; Y93-E130 WeakPolarHBondContact OH-CG 3.34Å; Y93-E130 PolarHBondContact OH-OE1 3.2Å; Y93-L178 HydrophobicContact CE2-CD1 3.87Å; Y93-W179 AromaticContact CD1-CZ2 3.74Å; Y93-W179 HydrophobicContact CD1-CZ2 3.74Å; Y93-W179 HydrophobicContact CD2-CZ2 4.2Å; Y93-W179 AromaticContact CE1-CE2 3.72Å; Y93-W179 AromaticContact CE1-CZ2 3.55Å; Y93-W179 HydrophobicContact CE1-CZ2 3.55Å; Y93-W179 AromaticContact CE1-NE1 3.36Å; Y93-W179 HydrophobicContact CE2-CZ2 4.06Å; Y93-W179 HydrophobicContact CG-CZ2 4.05Å; Y93-W179 AromaticContact CZ-CE2 3.83Å; Y93-W179 AromaticContact CZ-CZ2 3.72Å; Y93-W179 AromaticContact CZ-NE1 3.33Å; Y93-W179 VanDerWaalsContact CZ-NE1 3.33Å; Y93-W179 PolarHBondContact OH-NE1 3.22Å
94R98.1Very high97Very high91 Ų9151.5 Ų51.534%0.34325%0.252SS..EExtended strand (participates in β ladder)trans-75.2127.3164.9-164.8-179.8102.4176.96.3109.3T60 Y62 Y97 A119 H120 E122T60-R94 HydrophobicContact CG2-CG 3.74Å; Y62-R94 HydrophobicContact CD1-CB 4.32Å; Y62-R94 HydrophobicContact CE1-CB 4.26Å; Y62-R94 HydrophobicContact CE1-CG 4.32Å; R94-Y97 HydrophobicContact CB-CD1 4.39Å; R94-Y97 HydrophobicContact CG-CD1 3.95Å; R94-Y97 VanDerWaalsContact NH2-CD2 3.32Å; R94-Y97 WeakPolarHBondContact O-CE1 3.36Å; R94-A119 WeakPolarHBondContact O-CA 3.32Å; R94-H120 HydrophobicContact CB-CB 4.44Å; R94-H120 PolarHBondContact N-O 3.27Å; R94-H120 PolarHBondContact O-N 3.39Å; R94-E122 HydrophobicContact CB-CG 4.12Å; R94-E122 WeakPolarHBondContact CB-OE1 3.5Å
95V96.9Very high96.9Very high1 Ų152.2 Ų52.21%0.00626%0.256CS..EExtended strand (participates in β ladder)trans-129.5171-178.1-620000110.5V61 R63 Y97 A119V61-V95 HydrophobicContact CB-CG2 4.12Å; V61-V95 HydrophobicContact CG1-CG2 3.75Å; V61-V95 PolarHBondContact O-N 2.91Å; R63-V95 HydrophobicContact CB-CG1 3.93Å; R63-V95 HydrophobicContact CB-CG2 3.97Å; V95-Y97 PolarHBondContact O-N 3.15Å; V95-A119 HydrophobicContact CG1-CB 4.05Å
96R93.7Very high96.8Very high67 Ų6753.5 Ų53.525%0.25326%0.263SS..SBendtrans52.928174.5-57.8-174.4-179.9-94.8-6.6115.4V61 E417V61-R96 HydrophobicContact CB-CB 4.21Å; V61-R96 HydrophobicContact CG2-CB 4.08Å; R96-E417 IonicContact CZ-OE1 3.25Å; R96-E417 IonicContact NE-OE1 2.64Å; R96-E417 PolarHBondContact NE-OE1 3.04Å; R96-E417 IonicContact NH2-OE1 2.75Å; R96-E417 PolarHBondContact NH2-OE1 2.84Å
97Y93.5Very high96.5Very high70 Ų7054.8 Ų54.828%0.27528%0.281SS..  trans-93.9-1.3179.863-98.2000113.6R94 V95 V118 H120R94-Y97 HydrophobicContact CB-CD1 4.39Å; R94-Y97 HydrophobicContact CG-CD1 3.95Å; R94-Y97 VanDerWaalsContact NH2-CD2 3.32Å; R94-Y97 WeakPolarHBondContact O-CE1 3.36Å; V95-Y97 PolarHBondContact O-N 3.15Å; Y97-V118 HydrophobicContact CD1-CG1 4.06Å; Y97-V118 HydrophobicContact CE1-CB 4.5Å; Y97-V118 HydrophobicContact CE1-CG1 3.61Å; Y97-V118 HydrophobicContact CE1-CG2 4.19Å; Y97-V118 HydrophobicContact CE2-CG1 4.11Å; Y97-V118 WeakPolarHBondContact OH-CG2 3.41Å; Y97-H120 HydrophobicContact CE1-CB 3.96Å
98L95.1Very high96.3Very high68 Ų6854.9 Ų54.936%0.35628%0.283SS..SBendtrans-94.9146.6172.4-69.1178.2000110.4P116 V118L98-P116 HydrophobicContact CB-CB 4.43Å; L98-P116 HydrophobicContact CB-CG 3.72Å; L98-P116 HydrophobicContact CD1-CB 4.35Å; L98-V118 HydrophobicContact CB-CG1 4.42Å; L98-V118 HydrophobicContact CD1-CB 3.97Å; L98-V118 HydrophobicContact CD1-CG1 3.7Å; L98-V118 HydrophobicContact CD1-CG2 4.37Å; L98-V118 HydrophobicContact CG-CG1 3.83Å
99P95.5Very high96.1Very high53 Ų5352 Ų5234%0.34428%0.276SS..PPolyproline II helixtrans-64.6151.9176.527.8-34.5000111.9L55 V56 P116L55-P99 HydrophobicContact CD1-CB 4.04Å; L55-P99 HydrophobicContact CG-CB 4.11Å; L55-P99 WeakPolarHBondContact O-CA 3.25Å; V56-P99 VanDerWaalsContact CG2-CA 3.48Å; V56-P99 HydrophobicContact CG2-CB 3.57Å; V56-P99 HydrophobicContact CG2-CG 4.48Å; P99-P116 WeakPolarHBondContact O-CD 3.32Å; P99-P116 VanDerWaalsContact O-CG 3.26Å; P99-P116 WeakPolarHBondContact O-CG 3.38Å
100K96Very high96.1Very high18 Ų1851.1 Ų51.18%0.07827%0.268CS..PPolyproline II helixtrans-56.3140.7164.7-70.6169.9176.7154.60109.9W54 L55 I103 Y113 L115 D249W54-K100 HydrophobicContact CD2-CD 3.95Å; W54-K100 HydrophobicContact CE3-CD 4.28Å; W54-K100 HydrophobicContact CH2-CD 4.2Å; W54-K100 HydrophobicContact CZ2-CD 3.88Å; W54-K100 HydrophobicContact CZ3-CD 4.4Å; W54-K100 VanDerWaalsContact NE1-NZ 3.17Å; W54-K100 VanDerWaalsContact O-CD 3.25Å; W54-K100 WeakPolarHBondContact O-CD 3.41Å; W54-K100 VanDerWaalsContact O-CE 3.23Å; W54-K100 WeakPolarHBondContact O-CE 3.4Å; W54-K100 PolarHBondContact O-NZ 3.21Å; L55-K100 HydrophobicContact CD1-CB 4.32Å; L55-K100 PolarHBondContact O-N 3.07Å; K100-I103 HydrophobicContact CB-CD1 4.23Å; K100-I103 HydrophobicContact CB-CG1 4.47Å; K100-I103 WeakPolarHBondContact O-CD1 3.32Å; K100-Y113 HydrophobicContact CB-CD2 3.92Å; K100-Y113 HydrophobicContact CB-CG 4.36Å; K100-Y113 HydrophobicContact CD-CD1 4.48Å; K100-Y113 HydrophobicContact CD-CD2 3.42Å; K100-Y113 VanDerWaalsContact CD-CD2 3.42Å; K100-Y113 HydrophobicContact CD-CE2 3.54Å; K100-Y113 HydrophobicContact CD-CG 3.92Å; K100-Y113 HydrophobicContact CG-CD2 3.55Å; K100-Y113 HydrophobicContact CG-CE2 3.9Å; K100-Y113 HydrophobicContact CG-CG 4.32Å; K100-L115 HydrophobicContact CG-CD1 4.17Å; K100-D249 IonicContact NZ-OD2 3.55Å
101E96.2Very high96Very high66 Ų6649.5 Ų49.531%0.30826%0.257SS..EExtended strand (participates in β ladder)trans-118.4171.3-175.9-66.1-167.3-177.200112I103 M114 Y207E101-I103 PolarHBondContact O-N 3.38Å; E101-M114 PolarHBondContact N-O 3.13Å; E101-M114 PolarHBondContact O-N 3.27Å; E101-Y207 HydrophobicContact CB-CE1 4.35Å; E101-Y207 HydrophobicContact CG-CE1 4.47Å; E101-Y207 VanDerWaalsContact OE2-CE1 3.31Å; E101-Y207 WeakPolarHBondContact OE2-CE1 3.47Å; E101-Y207 PolarHBondContact OE2-OH 2.8Å
102N95.8Very high96Very high115 Ų11549.9 Ų49.962%0.61526%0.26SS*.EExtended strand (participates in β ladder)trans51.142.6-178.4-63.5-8.6000112.9T104 M114N102-T104 PolarHBondContact O-N 2.92Å; N102-M114 HydrophobicContact CB-CG 4.02Å
103I96.8Very high95.9Very high61 Ų6150.1 Ų50.131%0.31326%0.261SS..EExtended strand (participates in β ladder)trans-73.6126.4-175.4-63.1167.6000110W54 L55 K100 E101 I111 S112W54-I103 HydrophobicContact CH2-CD1 4.16Å; W54-I103 HydrophobicContact CH2-CG1 4.11Å; W54-I103 HydrophobicContact CH2-CG2 4.15Å; W54-I103 HydrophobicContact CZ3-CD1 3.86Å; W54-I103 HydrophobicContact CZ3-CG1 4.33Å; W54-I103 HydrophobicContact CZ3-CG2 4.38Å; L55-I103 HydrophobicContact CD1-CD1 3.3Å; K100-I103 HydrophobicContact CB-CD1 4.23Å; K100-I103 HydrophobicContact CB-CG1 4.47Å; K100-I103 WeakPolarHBondContact O-CD1 3.32Å; E101-I103 PolarHBondContact O-N 3.38Å; I103-I111 HydrophobicContact CG2-CD1 3.67Å; I103-I111 HydrophobicContact CG2-CG1 3.87Å; I103-S112 CarbonylContact C-O 3.58Å; I103-S112 VanDerWaalsContact CA-O 3.24Å; I103-S112 WeakPolarHBondContact CA-O 3.12Å
104T96.7Very high95.8Very high78 Ų7851.5 Ų51.548%0.47927%0.268SS..EExtended strand (participates in β ladder)trans-134.8119.1177.1-57.50000110.1N102 N106 I111 S112N102-T104 PolarHBondContact O-N 2.92Å; T104-N106 PolarHBondContact O-ND2 3.31Å; T104-I111 WeakPolarHBondContact O-CA 3.34Å; T104-S112 PolarHBondContact N-O 3.08Å; T104-S112 PolarHBondContact O-N 2.97Å
105E95.7Very high95.8Very high96 Ų9648.1 Ų48.145%0.44926%0.256SS..EExtended strand (participates in β ladder)trans-78.3136.4168.9-69.1-167.7-152.900110I111 K217E105-I111 HydrophobicContact CG-CD1 4.1Å; E105-I111 HydrophobicContact CG-CG1 4.27Å; E105-K217 IonicContact OE2-NZ 3.89Å; E105-K217 PolarHBondContact OE2-NZ 2.93Å
106N95.3Very high95.8Very high38 Ų3848.5 Ų48.520%0.20326%0.259CS..  trans-110.9152.2-178-58.5-89000110.9T104 D108 G109 T110 S112 R212T104-N106 PolarHBondContact O-ND2 3.31Å; N106-D108 WeakPolarHBondContact CB-OD1 3.19Å; N106-D108 PolarHBondContact O-N 3.32Å; N106-G109 PolarHBondContact O-N 3.19Å; N106-T110 WeakPolarHBondContact CB-O 3.19Å; N106-T110 VanDerWaalsContact CB-OG1 3.32Å; N106-T110 WeakPolarHBondContact CB-OG1 3.48Å; N106-T110 PolarHBondContact N-O 2.87Å; N106-T110 PolarHBondContact ND2-O 2.82Å; N106-T110 PolarHBondContact ND2-OG1 3.04Å; N106-S112 PolarHBondContact ND2-OG 2.97Å; N106-R212 PolarHBondContact ND2-NH1 2.84Å; N106-R212 PolarHBondContact OD1-NH1 3.24Å
107P92.9Very high95.9Very high136 Ų13646.7 Ų46.788%0.88325%0.254SS*.THydrogen-bonded Turntrans-62.7-23-179.1-24.434.6000115.3G109P107-G109 PolarHBondContact O-N 3.16Å
108D92.9Very high96Very high65 Ų6544.2 Ų44.235%0.34825%0.247SC..THydrogen-bonded Turntrans-87.223.2-178.571-23.8000113.3N106 T110 R212N106-D108 WeakPolarHBondContact CB-OD1 3.19Å; N106-D108 PolarHBondContact O-N 3.32Å; D108-T110 VanDerWaalsContact C-N 3.27Å; D108-T110 PolarHBondContact O-N 2.95Å; D108-T110 PolarHBondContact OD1-N 2.63Å; D108-T110 PolarHBondContact OD1-OG1 2.93Å; D108-R212 IonicContact OD1-CZ 2.8Å; D108-R212 IonicContact OD1-NH2 2.88Å; D108-R212 PolarHBondContact OD1-NH2 3.5Å; D108-R212 IonicContact OD2-CZ 3.62Å; D108-R212 IonicContact OD2-NE 3.64Å; D108-R212 IonicContact OD2-NH2 2.66Å; D108-R212 PolarHBondContact OD2-NH2 2.87Å
109G93.8Very high96.1Very high13 Ų1341.5 Ų41.513%0.13423%0.234CC..SBendtrans70.918178.600000114.5N106 P107 T215N106-G109 PolarHBondContact O-N 3.19Å; P107-G109 PolarHBondContact O-N 3.16Å; G109-T215 WeakPolarHBondContact O-CB 3.42Å; G109-T215 WeakPolarHBondContact O-CG2 3.14Å; G109-T215 PolarHBondContact O-N 3.39Å; G109-T215 PolarHBondContact O-OG1 2.67Å
110T97.4Very high96.2Very high1 Ų143.5 Ų43.51%0.00624%0.238CC..EExtended strand (participates in β ladder)trans-105.9157.2174.2670000112.8N106 D108 R212 V213 F214N106-T110 WeakPolarHBondContact CB-O 3.19Å; N106-T110 VanDerWaalsContact CB-OG1 3.32Å; N106-T110 WeakPolarHBondContact CB-OG1 3.48Å; N106-T110 PolarHBondContact N-O 2.87Å; N106-T110 PolarHBondContact ND2-O 2.82Å; N106-T110 PolarHBondContact ND2-OG1 3.04Å; D108-T110 VanDerWaalsContact C-N 3.27Å; D108-T110 PolarHBondContact O-N 2.95Å; D108-T110 PolarHBondContact OD1-N 2.63Å; D108-T110 PolarHBondContact OD1-OG1 2.93Å; T110-R212 HydrophobicContact CG2-CG 4.38Å; T110-R212 PolarHBondContact OG1-NE 2.98Å; T110-R212 VanDerWaalsContact OG1-NE 3.13Å; T110-R212 PolarHBondContact OG1-NH2 3.26Å; T110-R212 VanDerWaalsContact OG1-NH2 3.08Å; T110-V213 CarbonylContact C-O 3.34Å; T110-V213 WeakPolarHBondContact CA-O 3.35Å; T110-V213 WeakPolarHBondContact CB-O 3.43Å; T110-F214 HydrophobicContact CG2-CD1 3.64Å; T110-F214 HydrophobicContact CG2-CE1 3.82Å; T110-F214 HydrophobicContact CG2-CG 4.32Å
111I97.4Very high96.3Very high0 Ų044.2 Ų44.20%024%0.241CC..EExtended strand (participates in β ladder)trans-127.4132.6174.6-170.6168.9000109.3I44 F51 W54 I103 T104 E105 V213 T215I44-I111 HydrophobicContact CG2-CD1 4.33Å; I44-I111 HydrophobicContact CG2-CG2 4.12Å; F51-I111 HydrophobicContact CE2-CD1 3.95Å; W54-I111 HydrophobicContact CH2-CD1 3.58Å; W54-I111 HydrophobicContact CH2-CG1 3.95Å; W54-I111 HydrophobicContact CH2-CG2 4.36Å; W54-I111 HydrophobicContact CZ2-CD1 4.27Å; W54-I111 HydrophobicContact CZ2-CG1 4.39Å; W54-I111 HydrophobicContact CZ2-CG2 4.01Å; W54-I111 HydrophobicContact CZ3-CD1 3.87Å; I103-I111 HydrophobicContact CG2-CD1 3.67Å; I103-I111 HydrophobicContact CG2-CG1 3.87Å; T104-I111 WeakPolarHBondContact O-CA 3.34Å; E105-I111 HydrophobicContact CG-CD1 4.1Å; E105-I111 HydrophobicContact CG-CG1 4.27Å; I111-V213 HydrophobicContact CG2-CG2 3.51Å; I111-V213 PolarHBondContact N-O 2.95Å; I111-V213 PolarHBondContact O-N 3.49Å; I111-T215 HydrophobicContact CB-CG2 3.79Å; I111-T215 HydrophobicContact CG2-CG2 3.81Å
112S98.1Very high96.5Very high8 Ų842.9 Ų42.96%0.05624%0.235CC..EExtended strand (participates in β ladder)trans-106.3145.4-179.7-55.40000111.2I103 T104 N106 Y211I103-S112 CarbonylContact C-O 3.58Å; I103-S112 VanDerWaalsContact CA-O 3.24Å; I103-S112 WeakPolarHBondContact CA-O 3.12Å; T104-S112 PolarHBondContact N-O 3.08Å; T104-S112 PolarHBondContact O-N 2.97Å; N106-S112 PolarHBondContact ND2-OG 2.97Å; S112-Y211 CarbonylContact C-O 3.58Å; S112-Y211 WeakPolarHBondContact CA-O 3.28Å
113Y97.6Very high96.6Very high4 Ų441 Ų412%0.01623%0.229CC..EExtended strand (participates in β ladder)trans-158.7160.6-179.273.1-83.9000113.2W54 K100 L115 Y211 V213 D249W54-Y113 HydrophobicContact CH2-CD1 4.19Å; W54-Y113 HydrophobicContact CH2-CG 4.22Å; W54-Y113 AromaticContact CZ2-CD1 3.36Å; W54-Y113 HydrophobicContact CZ2-CD1 3.36Å; W54-Y113 AromaticContact CZ2-CE1 3.85Å; W54-Y113 HydrophobicContact CZ2-CE1 3.85Å; W54-Y113 AromaticContact CZ2-CG 3.76Å; W54-Y113 HydrophobicContact CZ2-CG 3.76Å; K100-Y113 HydrophobicContact CB-CD2 3.92Å; K100-Y113 HydrophobicContact CB-CG 4.36Å; K100-Y113 HydrophobicContact CD-CD1 4.48Å; K100-Y113 HydrophobicContact CD-CD2 3.42Å; K100-Y113 VanDerWaalsContact CD-CD2 3.42Å; K100-Y113 HydrophobicContact CD-CE2 3.54Å; K100-Y113 HydrophobicContact CD-CG 3.92Å; K100-Y113 HydrophobicContact CG-CD2 3.55Å; K100-Y113 HydrophobicContact CG-CE2 3.9Å; K100-Y113 HydrophobicContact CG-CG 4.32Å; Y113-L115 HydrophobicContact CE2-CB 4.39Å; Y113-Y211 HydrophobicContact CE1-CG 4.11Å; Y113-Y211 AromaticContact CE2-CD2 3.97Å; Y113-Y211 HydrophobicContact CE2-CD2 3.97Å; Y113-Y211 HydrophobicContact CE2-CG 4.16Å; Y113-Y211 AromaticContact CZ-CG 3.77Å; Y113-Y211 PolarHBondContact N-O 3.06Å; Y113-Y211 PolarHBondContact O-N 3.33Å; Y113-V213 HydrophobicContact CE1-CG1 3.98Å; Y113-V213 HydrophobicContact CE1-CG2 4.28Å; Y113-D249 PolarHBondContact OH-OD2 3.38Å
114M97.5Very high96.6Very high33 Ų3345.7 Ų45.716%0.16326%0.255CS..EExtended strand (participates in β ladder)trans-112.1142.9168.1-61.2-68.9-64.200109.4E101 N102 Y207 G209 L210E101-M114 PolarHBondContact N-O 3.13Å; E101-M114 PolarHBondContact O-N 3.27Å; N102-M114 HydrophobicContact CB-CG 4.02Å; M114-Y207 HydrophobicContact CB-CD1 4.04Å; M114-Y207 HydrophobicContact CB-CG 4.44Å; M114-Y207 VanDerWaalsContact CE-CB 3.45Å; M114-Y207 HydrophobicContact CE-CG 4.36Å; M114-G209 VanDerWaalsContact SD-C 3.59Å; M114-L210 HydrophobicContact CG-CD1 4.23Å; M114-L210 WeakPolarHBondContact SD-CA 3.35Å; M114-L210 HydrophobicContact SD-CB 3.87Å; M114-L210 HydrophobicContact SD-CD1 3.92Å; M114-L210 PolarHBondContact SD-N 3.24Å; M114-L210 VanDerWaalsContact SD-N 3.39Å
115L96.1Very high96.7Very high19 Ų1945.8 Ų45.810%0.09925%0.251CS..EExtended strand (participates in β ladder)trans-102.1113.3176.8-175.575000109.8K100 Y113 Y207 D208K100-L115 HydrophobicContact CG-CD1 4.17Å; Y113-L115 HydrophobicContact CE2-CB 4.39Å; L115-Y207 CarbonylContact O-C 3.54Å; L115-Y207 VanDerWaalsContact O-CA 3.26Å; L115-Y207 WeakPolarHBondContact O-CA 3.24Å; L115-D208 HydrophobicContact CB-CB 4.4Å; L115-D208 PolarHBondContact N-O 3.49Å; L115-D208 PolarHBondContact O-N 3.49Å
116P96.8Very high96.8Very high9 Ų942.2 Ų42.26%0.05824%0.237CC..EExtended strand (participates in β ladder)trans-69.1133.7176.826.4-32.9000111.7L98 P99 Y207L98-P116 HydrophobicContact CB-CB 4.43Å; L98-P116 HydrophobicContact CB-CG 3.72Å; L98-P116 HydrophobicContact CD1-CB 4.35Å; P99-P116 WeakPolarHBondContact O-CD 3.32Å; P99-P116 VanDerWaalsContact O-CG 3.26Å; P99-P116 WeakPolarHBondContact O-CG 3.38Å; P116-Y207 HydrophobicContact CB-CD1 3.96Å; P116-Y207 HydrophobicContact CB-CE1 3.79Å
117N96.3Very high97Very high30 Ų3045 Ų4516%0.1626%0.255CS..EExtended strand (participates in β ladder)trans-91.5116.7174.1-67.3-41.3000109.7Y203 N204 G205 T206N117-Y203 HydrophobicContact CB-CD1 4.3Å; N117-Y203 HydrophobicContact CB-CD2 4.1Å; N117-Y203 HydrophobicContact CB-CE1 4.14Å; N117-Y203 HydrophobicContact CB-CE2 3.93Å; N117-Y203 HydrophobicContact CB-CG 4.27Å; N117-Y203 VanDerWaalsContact CB-O 3.31Å; N117-Y203 WeakPolarHBondContact CB-O 3.34Å; N117-N204 WeakPolarHBondContact O-CA 3.29Å; N117-G205 PolarHBondContact O-N 3.39Å; N117-T206 WeakPolarHBondContact CB-OG1 3.45Å; N117-T206 PolarHBondContact N-O 2.72Å; N117-T206 PolarHBondContact ND2-OG1 2.8Å
118V96Very high97.2Very high18 Ų1839.6 Ų39.611%0.10922%0.223CC..  trans-144.4141.8175.669.50000110.5Y97 L98 N204Y97-V118 HydrophobicContact CD1-CG1 4.06Å; Y97-V118 HydrophobicContact CE1-CB 4.5Å; Y97-V118 HydrophobicContact CE1-CG1 3.61Å; Y97-V118 HydrophobicContact CE1-CG2 4.19Å; Y97-V118 HydrophobicContact CE2-CG1 4.11Å; Y97-V118 WeakPolarHBondContact OH-CG2 3.41Å; L98-V118 HydrophobicContact CB-CG1 4.42Å; L98-V118 HydrophobicContact CD1-CB 3.97Å; L98-V118 HydrophobicContact CD1-CG1 3.7Å; L98-V118 HydrophobicContact CD1-CG2 4.37Å; L98-V118 HydrophobicContact CG-CG1 3.83Å; V118-N204 WeakPolarHBondContact CA-OD1 3.41Å
119A97.6Very high97.5Very high10 Ų1039.8 Ų39.88%0.08323%0.227CC..EExtended strand (participates in β ladder)trans-133.4129.6172.700000109.9Y93 R94 V95 W179 Y203 N204Y93-A119 HydrophobicContact CD1-CB 3.92Å; Y93-A119 HydrophobicContact CG-CB 4.34Å; R94-A119 WeakPolarHBondContact O-CA 3.32Å; V95-A119 HydrophobicContact CG1-CB 4.05Å; A119-W179 HydrophobicContact CB-CH2 3.61Å; A119-W179 HydrophobicContact CB-CZ2 3.82Å; A119-W179 HydrophobicContact CB-CZ3 4.35Å; A119-Y203 HydrophobicContact CB-CD1 4.09Å; A119-Y203 HydrophobicContact CB-CE1 3.91Å; A119-N204 PolarHBondContact N-OD1 2.81Å; A119-N204 PolarHBondContact O-ND2 3.31Å
120H97.8Very high97.7Very high95 Ų9541 Ų4144%0.4423%0.229SC..EExtended strand (participates in β ladder)trans-116.7123.5174.2179.2-92.6000109.1Y93 R94 Y97 E122Y93-H120 CarbonylContact C-O 3.53Å; Y93-H120 WeakPolarHBondContact CA-O 3.5Å; R94-H120 HydrophobicContact CB-CB 4.44Å; R94-H120 PolarHBondContact N-O 3.27Å; R94-H120 PolarHBondContact O-N 3.39Å; Y97-H120 HydrophobicContact CE1-CB 3.96Å; H120-E122 IonicContact CE1-OE1 2.62Å; H120-E122 IonicContact ND1-OE1 3.91Å; H120-E122 PolarHBondContact ND1-OE1 3.25Å; H120-E122 VanDerWaalsContact ND1-OE1 3.09Å
121F98.6Very high97.7Very high34 Ų3446.4 Ų46.415%0.14926%0.258CS..EExtended strand (participates in β ladder)trans-71.5136.6-177-176.5-116.4000111.5Y91 T92 Y93 P123 S126 G128 E130Y91-F121 HydrophobicContact CD1-CE2 4.44Å; T92-F121 VanDerWaalsContact O-CD2 3.32Å; T92-F121 WeakPolarHBondContact O-CD2 3.44Å; Y93-F121 HydrophobicContact CD1-CB 3.9Å; Y93-F121 HydrophobicContact CD1-CD2 4.2Å; Y93-F121 HydrophobicContact CD2-CD2 4.18Å; Y93-F121 HydrophobicContact CE1-CB 3.66Å; Y93-F121 AromaticContact CE1-CD2 3.79Å; Y93-F121 HydrophobicContact CE1-CD2 3.79Å; Y93-F121 HydrophobicContact CE1-CG 4.16Å; Y93-F121 AromaticContact CE2-CD2 3.75Å; Y93-F121 HydrophobicContact CE2-CD2 3.75Å; Y93-F121 HydrophobicContact CE2-CE2 4.28Å; Y93-F121 HydrophobicContact CG-CD2 4.39Å; Y93-F121 AromaticContact CZ-CD2 3.55Å; F121-P123 HydrophobicContact CD1-CB 4.38Å; F121-P123 HydrophobicContact CE1-CB 3.92Å; F121-P123 WeakPolarHBondContact O-CD 3.36Å; F121-S126 VanDerWaalsContact CE2-OG 3.25Å; F121-S126 WeakPolarHBondContact CE2-OG 3.36Å; F121-S126 WeakPolarHBondContact CZ-OG 3.21Å; F121-G128 WeakPolarHBondContact CZ-O 3.46Å; F121-E130 HydrophobicContact CB-CG 4.32Å; F121-E130 HydrophobicContact CD1-CG 3.87Å; F121-E130 HydrophobicContact CD2-CG 3.88Å; F121-E130 HydrophobicContact CE1-CG 4.11Å; F121-E130 HydrophobicContact CE2-CG 4.13Å; F121-E130 HydrophobicContact CG-CG 3.74Å; F121-E130 HydrophobicContact CZ-CG 4.23Å
122E98.5Very high97.8Very high38 Ų3848.1 Ų48.118%0.17827%0.267CS..  trans-11491.7-179.6-61.1-65160.200109.1Y62 T92 R94 H120 D124 M125 S126Y62-E122 HydrophobicContact CD1-CG 4.39Å; Y62-E122 HydrophobicContact CE1-CG 4.09Å; T92-E122 HydrophobicContact CG2-CB 4.14Å; T92-E122 PolarHBondContact O-N 2.81Å; R94-E122 HydrophobicContact CB-CG 4.12Å; R94-E122 WeakPolarHBondContact CB-OE1 3.5Å; H120-E122 IonicContact CE1-OE1 2.62Å; H120-E122 IonicContact ND1-OE1 3.91Å; H120-E122 PolarHBondContact ND1-OE1 3.25Å; H120-E122 VanDerWaalsContact ND1-OE1 3.09Å; E122-D124 VanDerWaalsContact C-N 3.34Å; E122-D124 PolarHBondContact O-N 2.67Å; E122-M125 HydrophobicContact CB-CB 4.23Å; E122-M125 HydrophobicContact CB-CG 4.5Å; E122-M125 HydrophobicContact CB-SD 4.48Å; E122-M125 PolarHBondContact O-N 2.87Å; E122-S126 PolarHBondContact O-N 3.49Å; E122-S126 PolarHBondContact O-OG 2.91Å
123P97.8Very high97.8Very high76 Ų7651.4 Ų51.449%0.49429%0.287SS..G310 helixtrans-63.3-38.6-173.924.2-33.2000112.4F121 M125 S126F121-P123 HydrophobicContact CD1-CB 4.38Å; F121-P123 HydrophobicContact CE1-CB 3.92Å; F121-P123 WeakPolarHBondContact O-CD 3.36Å; P123-M125 PolarHBondContact O-N 2.84Å; P123-M125 VanDerWaalsContact O-N 3.16Å; P123-S126 PolarHBondContact O-N 3.14Å
124D98.1Very high97.8Very high159 Ų15951.2 Ų51.285%0.8529%0.286SS*.G310 helixtrans-68.5-15-177.9-59.3-31000113.4E122E122-D124 VanDerWaalsContact C-N 3.34Å; E122-D124 PolarHBondContact O-N 2.67Å
125M98.1Very high97.8Very high80 Ų8051 Ų5139%0.39429%0.287SS..G310 helixtrans-108.711.5176.9-61.1-178.868.200112.1Y62 T92 E122 P123Y62-M125 HydrophobicContact CD1-CE 4.28Å; Y62-M125 HydrophobicContact CD1-SD 4.21Å; Y62-M125 HydrophobicContact CD2-CE 4.38Å; Y62-M125 HydrophobicContact CE1-CE 4.15Å; Y62-M125 HydrophobicContact CE1-SD 3.66Å; Y62-M125 HydrophobicContact CE2-CE 4.26Å; Y62-M125 HydrophobicContact CG-CE 4.38Å; T92-M125 WeakPolarHBondContact CB-O 3.31Å; T92-M125 HydrophobicContact CG2-CB 3.83Å; T92-M125 HydrophobicContact CG2-CE 4.27Å; T92-M125 HydrophobicContact CG2-SD 4.37Å; T92-M125 PolarHBondContact OG1-O 2.93Å; E122-M125 HydrophobicContact CB-CB 4.23Å; E122-M125 HydrophobicContact CB-CG 4.5Å; E122-M125 HydrophobicContact CB-SD 4.48Å; E122-M125 PolarHBondContact O-N 2.87Å; P123-M125 PolarHBondContact O-N 2.84Å; P123-M125 VanDerWaalsContact O-N 3.16Å
126S98.7Very high97.9Very high21 Ų2150.2 Ų50.215%0.14728%0.283CS..SBendtrans-117.4148-175.3-61.30000111.4P90 T92 F121 E122 P123 G128P90-S126 CarbonylContact O-C 3.55Å; P90-S126 VanDerWaalsContact O-CA 3.27Å; P90-S126 WeakPolarHBondContact O-CA 3.07Å; T92-S126 PolarHBondContact N-OG 3.19Å; F121-S126 VanDerWaalsContact CE2-OG 3.25Å; F121-S126 WeakPolarHBondContact CE2-OG 3.36Å; F121-S126 WeakPolarHBondContact CZ-OG 3.21Å; E122-S126 PolarHBondContact O-N 3.49Å; E122-S126 PolarHBondContact O-OG 2.91Å; P123-S126 PolarHBondContact O-N 3.14Å; S126-G128 WeakPolarHBondContact CB-O 3.35Å; S126-G128 PolarHBondContact O-N 3.29Å
127V98.4Very high97.9Very high97 Ų9749.8 Ų49.859%0.58828%0.28SS*.SBendtrans-68.9-22.7177.670.20000112.9P90 Y91P90-V127 PolarHBondContact O-N 2.95Å; Y91-V127 HydrophobicContact CE1-CG1 4.29Å; Y91-V127 HydrophobicContact CE2-CG1 4.33Å
128G97.7Very high98Very high21 Ų2148.6 Ų48.622%0.21627%0.274CS..SBendtrans-165.2-160.3-177.400000111.5F121 S126 D132F121-G128 WeakPolarHBondContact CZ-O 3.46Å; S126-G128 WeakPolarHBondContact CB-O 3.35Å; S126-G128 PolarHBondContact O-N 3.29Å; G128-D132 WeakPolarHBondContact CA-OD2 3.32Å
129T98.3Very high98.1Very high70 Ų7048.7 Ų48.743%0.42927%0.273SS..  trans-100.1163-172.971.50000112.6Y91 N131 D132Y91-T129 WeakPolarHBondContact CE1-O 3.49Å; T129-N131 PolarHBondContact O-N 3.29Å; T129-N131 PolarHBondContact OG1-N 2.86Å; T129-D132 VanDerWaalsContact N-CG 3.35Å; T129-D132 PolarHBondContact N-OD1 3.18Å; T129-D132 PolarHBondContact N-OD2 2.82Å; T129-D132 WeakPolarHBondContact O-CB 3.46Å; T129-D132 PolarHBondContact O-N 3.47Å; T129-D132 VanDerWaalsContact O-N 3.09Å; T129-D132 PolarHBondContact OG1-N 2.88Å; T129-D132 PolarHBondContact OG1-OD1 3.32Å
130E98.1Very high98.1Very high38 Ų3848.4 Ų48.418%0.17827%0.271CS..THydrogen-bonded Turntrans-57.7-18.1168.7-74.2-164.1112.200113.7Y93 F121 T173 V174 K175Y93-E130 WeakPolarHBondContact OH-CG 3.34Å; Y93-E130 PolarHBondContact OH-OE1 3.2Å; F121-E130 HydrophobicContact CB-CG 4.32Å; F121-E130 HydrophobicContact CD1-CG 3.87Å; F121-E130 HydrophobicContact CD2-CG 3.88Å; F121-E130 HydrophobicContact CE1-CG 4.11Å; F121-E130 HydrophobicContact CE2-CG 4.13Å; F121-E130 HydrophobicContact CG-CG 3.74Å; F121-E130 HydrophobicContact CZ-CG 4.23Å; E130-T173 WeakPolarHBondContact O-CB 3.4Å; E130-V174 PolarHBondContact O-N 3.28Å; E130-K175 HydrophobicContact CB-CB 4.09Å; E130-K175 HydrophobicContact CB-CD 4.49Å; E130-K175 WeakPolarHBondContact O-CB 3.32Å; E130-K175 PolarHBondContact O-N 2.98Å; E130-K175 IonicContact OE2-NZ 3.02Å; E130-K175 PolarHBondContact OE2-NZ 3.48Å
131N98.4Very high98.1Very high115 Ų11543.9 Ų43.962%0.61525%0.25SS*.THydrogen-bonded Turntrans-90.9-4.4-179.8-66.2-28.9000113.5T129 T133T129-N131 PolarHBondContact O-N 3.29Å; T129-N131 PolarHBondContact OG1-N 2.86Å; N131-T133 PolarHBondContact O-N 3.08Å
132D98.5Very high98Very high35 Ų3542.5 Ų42.519%0.18725%0.245CC..  trans-57.2131.2176.1-68.710.2000109.5R88 Y91 G128 T129 T173 V174R88-D132 IonicContact NH2-OD2 3.05Å; Y91-D132 HydrophobicContact CE1-CB 4.22Å; Y91-D132 WeakPolarHBondContact CE1-OD2 3.4Å; Y91-D132 VanDerWaalsContact OH-CB 3.29Å; Y91-D132 WeakPolarHBondContact OH-CB 3.21Å; Y91-D132 PolarHBondContact OH-OD2 3.02Å; G128-D132 WeakPolarHBondContact CA-OD2 3.32Å; T129-D132 VanDerWaalsContact N-CG 3.35Å; T129-D132 PolarHBondContact N-OD1 3.18Å; T129-D132 PolarHBondContact N-OD2 2.82Å; T129-D132 WeakPolarHBondContact O-CB 3.46Å; T129-D132 PolarHBondContact O-N 3.47Å; T129-D132 VanDerWaalsContact O-N 3.09Å; T129-D132 PolarHBondContact OG1-N 2.88Å; T129-D132 PolarHBondContact OG1-OD1 3.32Å; D132-T173 CarbonylContact O-C 3.52Å; D132-T173 WeakPolarHBondContact O-CA 3.46Å; D132-V174 HydrophobicContact CB-CG2 4.05Å; D132-V174 PolarHBondContact O-N 2.98Å
133T98.3Very high97.9Very high77 Ų7741.2 Ų41.247%0.47224%0.241SC..EExtended strand (participates in β ladder)trans-93.2138.5-178.2-570000110.4R88 N131 N171 R172R88-T133 PolarHBondContact NH1-O 3.09Å; N131-T133 PolarHBondContact O-N 3.08Å; T133-N171 HydrophobicContact CG2-CB 3.85Å; T133-R172 WeakPolarHBondContact CA-O 3.22Å
134I97.9Very high97.8Very high1 Ų138 Ų381%0.00522%0.22CC..EExtended strand (participates in β ladder)trans-132.8139.2-178.4-60-178.5000108.7I67 D69 R88 Y91 C136 N171 R172 V174I67-I134 HydrophobicContact CB-CD1 3.69Å; I67-I134 HydrophobicContact CD1-CD1 3.78Å; I67-I134 HydrophobicContact CG1-CD1 4.32Å; I67-I134 HydrophobicContact CG2-CD1 3.82Å; I67-I134 HydrophobicContact CG2-CG2 3.94Å; D69-I134 HydrophobicContact CB-CG2 3.74Å; D69-I134 WeakPolarHBondContact OD1-CG2 3.27Å; R88-I134 HydrophobicContact CB-CD1 4.42Å; Y91-I134 HydrophobicContact CE2-CD1 4.42Å; I134-C136 HydrophobicContact CG2-CB 4.47Å; I134-N171 WeakPolarHBondContact O-CA 3.47Å; I134-R172 PolarHBondContact N-O 3.4Å; I134-R172 PolarHBondContact O-N 2.02Å; I134-V174 HydrophobicContact CD1-CG2 3.83Å; I134-V174 HydrophobicContact CG1-CG2 4.48Å
135T98.6Very high97.6Very high28 Ų2830.9 Ų30.917%0.17218%0.183CC..EExtended strand (participates in β ladder)trans-84.9110.2170.8-49.90000108.4D69 V70 P73 Q170 N171D69-T135 WeakPolarHBondContact OD1-CA 3.47Å; D69-T135 WeakPolarHBondContact OD1-CB 3.28Å; D69-T135 PolarHBondContact OD1-N 3.36Å; V70-T135 HydrophobicContact CB-CG2 4.1Å; V70-T135 WeakPolarHBondContact CG2-O 3.49Å; V70-T135 PolarHBondContact N-O 3.34Å; P73-T135 HydrophobicContact CB-CG2 3.97Å; P73-T135 HydrophobicContact CG-CG2 4.31Å; T135-Q170 WeakPolarHBondContact CA-O 3.46Å; T135-N171 PolarHBondContact OG1-OD1 3.46Å
136C97.6Very high97.3Very high2 Ų228.7 Ų28.71%0.01418%0.177CC..EExtended strand (participates in β ladder)trans-133.7173.3-173.864.20000112I134 L169 Q170I134-C136 HydrophobicContact CG2-CB 4.47Å; C136-L169 CarbonylContact O-C 3.58Å; C136-L169 WeakPolarHBondContact O-CA 3.2Å; C136-Q170 PolarHBondContact N-O 3.46Å; C136-Q170 PolarHBondContact O-N 3.09Å
137L97.8Very high96.9Very high1 Ų130.9 Ų30.91%0.00519%0.187CC..EExtended strand (participates in β ladder)trans-64.7137.5176.8-164.169.7000111.3L139 V142 M168 L169 Q170 L390 V392 F410 I412L137-L139 PolarHBondContact O-N 3.39Å; L137-L139 VanDerWaalsContact O-N 3.08Å; L137-V142 HydrophobicContact CD1-CG2 3.85Å; L137-V142 HydrophobicContact CD2-CB 4.35Å; L137-V142 HydrophobicContact CD2-CG1 4.36Å; L137-V142 HydrophobicContact CD2-CG2 3.93Å; L137-V142 HydrophobicContact CG-CG2 3.81Å; L137-M168 HydrophobicContact CD1-CE 3.8Å; L137-M168 HydrophobicContact CD1-CG 3.92Å; L137-L169 HydrophobicContact CD1-CD2 4.16Å; L137-Q170 PolarHBondContact O-NE2 3.01Å; L137-L390 HydrophobicContact CD2-CB 3.92Å; L137-L390 HydrophobicContact CD2-CD2 3.84Å; L137-L390 HydrophobicContact CD2-CG 4.44Å; L137-V392 HydrophobicContact CD1-CG2 4.27Å; L137-V392 HydrophobicContact CD2-CG2 4.03Å; L137-F410 HydrophobicContact CB-CD1 4.07Å; L137-F410 HydrophobicContact CB-CE1 4.04Å; L137-F410 HydrophobicContact CB-CZ 4.46Å; L137-F410 HydrophobicContact CD1-CD2 4.05Å; L137-F410 HydrophobicContact CD1-CE2 4.24Å; L137-F410 HydrophobicContact CD1-CG 4.24Å; L137-F410 HydrophobicContact CD2-CB 4.02Å; L137-F410 HydrophobicContact CD2-CD1 4.1Å; L137-F410 HydrophobicContact CD2-CG 4Å; L137-F410 HydrophobicContact CG-CD1 4.5Å; L137-I412 HydrophobicContact CB-CD1 3.66Å; L137-I412 HydrophobicContact CD2-CD1 3.8Å; L137-I412 HydrophobicContact CG-CD1 4.41Å
138N98.4Very high96.6Very high4 Ų432.2 Ų32.22%0.02118%0.182CC..  trans-75.598.1169.4-171-36.9000110.4A140 V141 V142 V167 M168 Q170N138-A140 VanDerWaalsContact C-N 3.29Å; N138-A140 PolarHBondContact O-N 3.33Å; N138-A140 PolarHBondContact OD1-N 3.26Å; N138-V141 HydrophobicContact CB-CB 3.91Å; N138-V141 HydrophobicContact CB-CG2 4.05Å; N138-V141 WeakPolarHBondContact ND2-CG2 3.49Å; N138-V141 PolarHBondContact O-N 3.31Å; N138-V141 WeakPolarHBondContact OD1-CG2 3.39Å; N138-V141 PolarHBondContact OD1-N 3.23Å; N138-V142 PolarHBondContact O-N 3.33Å; N138-V142 VanDerWaalsContact O-N 3.07Å; N138-V167 WeakPolarHBondContact CB-O 3.26Å; N138-V167 PolarHBondContact ND2-O 3.08Å; N138-M168 WeakPolarHBondContact CB-O 3.19Å; N138-M168 PolarHBondContact N-O 3.35Å; N138-Q170 HydrophobicContact CB-CB 4.41Å; N138-Q170 HydrophobicContact CB-CG 4.05Å
139L98Very high96.2Very high20 Ų2036.8 Ų36.811%0.10521%0.206CC..Hα-helixtrans-57.5-39.3-175.2-53.7-177.5000112.5L137 A143 I177 L197 V199 L390 I412L137-L139 PolarHBondContact O-N 3.39Å; L137-L139 VanDerWaalsContact O-N 3.08Å; L139-A143 WeakPolarHBondContact O-CB 3.5Å; L139-A143 PolarHBondContact O-N 3.15Å; L139-I177 HydrophobicContact CD1-CD1 3.74Å; L139-I177 HydrophobicContact CG-CD1 4.1Å; L139-L197 HydrophobicContact CB-CD1 3.58Å; L139-L197 HydrophobicContact CD1-CD1 3.65Å; L139-L197 HydrophobicContact CG-CD1 4.1Å; L139-V199 HydrophobicContact CD1-CG2 4.25Å; L139-L390 HydrophobicContact CD2-CD2 4.09Å; L139-I412 HydrophobicContact CD2-CD1 3.96Å; L139-I412 HydrophobicContact CD2-CG1 4.38Å
140A97.3Very high95.9Very high5 Ų537.9 Ų37.94%0.04121%0.21CC..Hα-helixtrans-71.3-44.6179.500000112.1N138 V142 A143 A144 D183 F185 L186 L197N138-A140 VanDerWaalsContact C-N 3.29Å; N138-A140 PolarHBondContact O-N 3.33Å; N138-A140 PolarHBondContact OD1-N 3.26Å; A140-V142 PolarHBondContact O-N 2.82Å; A140-A143 PolarHBondContact O-N 3.48Å; A140-A144 WeakPolarHBondContact O-CB 3.32Å; A140-A144 PolarHBondContact O-N 2.87Å; A140-D183 HydrophobicContact CB-CB 4.37Å; A140-F185 HydrophobicContact CB-CD1 3.67Å; A140-F185 HydrophobicContact CB-CE1 3.97Å; A140-L186 HydrophobicContact CB-CD1 4.18Å; A140-L186 HydrophobicContact CB-CD2 3.97Å; A140-L186 HydrophobicContact CB-CG 3.84Å; A140-L197 HydrophobicContact CB-CD2 3.67Å
141V97.2Very high95.6Very high0 Ų038.6 Ų38.60%022%0.222CC..Hα-helixtrans-60.7-34.2179.4169.60000111.3N138 P145 M161 F185 A400 L401N138-V141 HydrophobicContact CB-CB 3.91Å; N138-V141 HydrophobicContact CB-CG2 4.05Å; N138-V141 WeakPolarHBondContact ND2-CG2 3.49Å; N138-V141 PolarHBondContact O-N 3.31Å; N138-V141 WeakPolarHBondContact OD1-CG2 3.39Å; N138-V141 PolarHBondContact OD1-N 3.23Å; V141-P145 WeakPolarHBondContact O-CD 3.04Å; V141-P145 WeakPolarHBondContact O-CG 3.44Å; V141-M161 HydrophobicContact CB-CE 4.37Å; V141-M161 HydrophobicContact CB-SD 4.49Å; V141-M161 HydrophobicContact CG1-CE 4.34Å; V141-M161 HydrophobicContact CG1-SD 4.06Å; V141-M161 HydrophobicContact CG2-CE 4.36Å; V141-M161 HydrophobicContact CG2-CG 4.35Å; V141-M161 HydrophobicContact CG2-SD 4.21Å; V141-F185 HydrophobicContact CG2-CD1 4.41Å; V141-A400 HydrophobicContact CG1-CB 3.81Å; V141-L401 HydrophobicContact CG1-CD2 4.23Å; V141-L401 HydrophobicContact CG1-CG 4.26Å
142V96.5Very high95.3Very high5 Ų539.5 Ų39.53%0.0322%0.22CC..Hα-helixtrans-85.3-41.8178175.30000112.8L137 N138 A140 P145 L390 V392 L401L137-V142 HydrophobicContact CD1-CG2 3.85Å; L137-V142 HydrophobicContact CD2-CB 4.35Å; L137-V142 HydrophobicContact CD2-CG1 4.36Å; L137-V142 HydrophobicContact CD2-CG2 3.93Å; L137-V142 HydrophobicContact CG-CG2 3.81Å; N138-V142 PolarHBondContact O-N 3.33Å; N138-V142 VanDerWaalsContact O-N 3.07Å; A140-V142 PolarHBondContact O-N 2.82Å; V142-P145 WeakPolarHBondContact O-CD 3.28Å; V142-L390 HydrophobicContact CB-CD2 3.76Å; V142-L390 HydrophobicContact CG1-CD2 3.59Å; V142-L390 HydrophobicContact CG1-CG 4.06Å; V142-V392 HydrophobicContact CG1-CB 4.49Å; V142-V392 HydrophobicContact CG1-CG2 4.12Å; V142-V392 HydrophobicContact CG2-CG2 4.46Å; V142-L401 HydrophobicContact CG2-CD2 4.2Å
143A96.3Very high95Very high11 Ų1140.2 Ų40.29%0.09122%0.224CC..Hα-helixtrans-75.8-38.8-174.500000113.4L139 A140 A146 L147 R336L139-A143 WeakPolarHBondContact O-CB 3.5Å; L139-A143 PolarHBondContact O-N 3.15Å; A140-A143 PolarHBondContact O-N 3.48Å; A143-A146 PolarHBondContact O-N 3.47Å; A143-L147 WeakPolarHBondContact O-CG 3.13Å; A143-L147 PolarHBondContact O-N 2.82Å; A143-L147 VanDerWaalsContact O-N 3.09Å; A143-R336 HydrophobicContact CB-CG 4.42Å
144A95.2Very high94.8Very high7 Ų737.4 Ų37.46%0.05821%0.205CC..Hα-helixtrans-62.3-43.6-175.800000113.1A140 A146 L147 Y148 L157 F185A140-A144 WeakPolarHBondContact O-CB 3.32Å; A140-A144 PolarHBondContact O-N 2.87Å; A144-A146 VanDerWaalsContact C-N 3.28Å; A144-A146 PolarHBondContact O-N 3.48Å; A144-L147 PolarHBondContact O-N 2.84Å; A144-Y148 VanDerWaalsContact O-CD2 3.26Å; A144-Y148 WeakPolarHBondContact O-CD2 3.42Å; A144-Y148 PolarHBondContact O-N 3.41Å; A144-L157 HydrophobicContact CB-CD1 4.45Å; A144-L157 HydrophobicContact CB-CD2 4.29Å; A144-F185 HydrophobicContact CB-CE1 3.83Å; A144-F185 HydrophobicContact CB-CZ 3.84Å
145P93.7Very high94.7Very high10 Ų1041.9 Ų41.97%0.06523%0.229CC..Hα-helixtrans-66.5-29.1176.9-24.638.7000113.6V141 V142 Q154 M161 A395 I398 L401V141-P145 WeakPolarHBondContact O-CD 3.04Å; V141-P145 WeakPolarHBondContact O-CG 3.44Å; V142-P145 WeakPolarHBondContact O-CD 3.28Å; P145-Q154 PolarHBondContact O-NE2 2.84Å; P145-M161 HydrophobicContact CG-CE 4.06Å; P145-A395 HydrophobicContact CB-CB 4.41Å; P145-I398 HydrophobicContact CB-CD1 3.59Å; P145-I398 HydrophobicContact CG-CD1 3.2Å; P145-L401 HydrophobicContact CB-CD1 4.41Å; P145-L401 HydrophobicContact CG-CD1 4Å
146A91.6Very high94.5Very high34 Ų3442.7 Ų42.728%0.28123%0.232SC..Hα-helixtrans-70.3-34.8174.900000112.1A143 A144 P337A143-A146 PolarHBondContact O-N 3.47Å; A144-A146 VanDerWaalsContact C-N 3.28Å; A144-A146 PolarHBondContact O-N 3.48Å; A146-P337 HydrophobicContact CB-CB 4.18Å; A146-P337 HydrophobicContact CB-CG 3.77Å
147L91.9Very high94.4Very high68 Ų6842.8 Ų42.836%0.35623%0.232SC..Hα-helixtrans-76.5-38.1176.2-72.9170.3000112.8A143 A144 G335 R336A143-L147 WeakPolarHBondContact O-CG 3.13Å; A143-L147 PolarHBondContact O-N 2.82Å; A143-L147 VanDerWaalsContact O-N 3.09Å; A144-L147 PolarHBondContact O-N 2.84Å; L147-G335 VanDerWaalsContact CD2-O 3.29Å; L147-G335 WeakPolarHBondContact CD2-O 3.07Å; L147-R336 HydrophobicContact CD1-CG 4.11Å
148Y91.3Very high94.4Very high125 Ų12543.6 Ų43.649%0.4924%0.236SC..  trans-116.782.7-172.6-57.7-72000111.2A144 N150 I153 Q154A144-Y148 VanDerWaalsContact O-CD2 3.26Å; A144-Y148 WeakPolarHBondContact O-CD2 3.42Å; A144-Y148 PolarHBondContact O-N 3.41Å; Y148-N150 VanDerWaalsContact C-N 3.32Å; Y148-N150 PolarHBondContact O-N 2.78Å; Y148-I153 HydrophobicContact CG-CG2 4.13Å; Y148-Q154 PolarHBondContact O-NE2 2.74Å
149T89.2Confident94.3Very high117 Ų11746.9 Ų46.972%0.71826%0.257SS*.  trans-79.1-12.4-176.256.80000114.1A151T149-A151 PolarHBondContact O-N 3.49Å
150N92.5Very high94.2Very high93 Ų9347.9 Ų47.950%0.49726%0.259SS..  trans-58.5129.6179.4179.1-71.5000111.5Y148 F152 I153 Q154Y148-N150 VanDerWaalsContact C-N 3.32Å; Y148-N150 PolarHBondContact O-N 2.78Å; N150-F152 VanDerWaalsContact C-N 3.32Å; N150-F152 PolarHBondContact O-N 2.93Å; N150-F152 WeakPolarHBondContact OD1-CB 3.41Å; N150-F152 PolarHBondContact OD1-N 2.86Å; N150-I153 HydrophobicContact CB-CB 4.22Å; N150-I153 HydrophobicContact CB-CG1 3.97Å; N150-I153 PolarHBondContact O-N 3.31Å; N150-I153 VanDerWaalsContact O-N 3.13Å; N150-I153 PolarHBondContact OD1-N 2.84Å; N150-Q154 VanDerWaalsContact O-CG 3.27Å; N150-Q154 WeakPolarHBondContact O-CG 3.38Å; N150-Q154 PolarHBondContact O-N 3.01Å
151A91.4Very high94.2Very high52 Ų5247.8 Ų47.843%0.4326%0.258SS..Hα-helixtrans-55.3-39.2-175.800000115T149 L155T149-A151 PolarHBondContact O-N 3.49Å; A151-L155 PolarHBondContact O-N 3.04Å
152F92.9Very high94.2Very high134 Ų13453 Ų5359%0.58828%0.28SS*.Hα-helixtrans-73-42.3178.8176.5-104.7000110.8N150 Q154 L155 L156N150-F152 VanDerWaalsContact C-N 3.32Å; N150-F152 PolarHBondContact O-N 2.93Å; N150-F152 WeakPolarHBondContact OD1-CB 3.41Å; N150-F152 PolarHBondContact OD1-N 2.86Å; F152-Q154 VanDerWaalsContact C-N 3.33Å; F152-Q154 PolarHBondContact O-N 2.81Å; F152-L155 WeakPolarHBondContact O-CB 3.3Å; F152-L155 PolarHBondContact O-N 2.84Å; F152-L156 HydrophobicContact CD1-CD1 4.16Å; F152-L156 HydrophobicContact CE1-CD1 3.62Å; F152-L156 HydrophobicContact CE1-CG 4.26Å; F152-L156 HydrophobicContact CZ-CD1 4.06Å; F152-L156 HydrophobicContact CZ-CD2 4.44Å; F152-L156 HydrophobicContact CZ-CG 4.36Å; F152-L156 PolarHBondContact O-N 3.37Å
153I92.1Very high94.2Very high50 Ų5056.3 Ų56.326%0.25630%0.304SS..Hα-helixtrans-62.2-41.8175.6-58.3-60.1000110.9Y148 N150 L155 L156 L157Y148-I153 HydrophobicContact CG-CG2 4.13Å; N150-I153 HydrophobicContact CB-CB 4.22Å; N150-I153 HydrophobicContact CB-CG1 3.97Å; N150-I153 PolarHBondContact O-N 3.31Å; N150-I153 VanDerWaalsContact O-N 3.13Å; N150-I153 PolarHBondContact OD1-N 2.84Å; I153-L155 VanDerWaalsContact C-N 3.27Å; I153-L155 PolarHBondContact O-N 3.02Å; I153-L156 HydrophobicContact CD1-CD1 4.41Å; I153-L156 WeakPolarHBondContact O-CB 3.37Å; I153-L156 PolarHBondContact O-N 3.27Å; I153-L157 HydrophobicContact CG2-CD1 4.11Å; I153-L157 HydrophobicContact CG2-CG 4.06Å; I153-L157 VanDerWaalsContact O-CG 3.3Å; I153-L157 WeakPolarHBondContact O-CG 3.08Å; I153-L157 PolarHBondContact O-N 3.03Å
154Q94.1Very high94.2Very high18 Ų1856.8 Ų56.88%0.08431%0.307CS..Hα-helixtrans-56.1-39175.3-70.9-86.6-22.600112.9P145 Y148 N150 F152 L157 N158 K397P145-Q154 PolarHBondContact O-NE2 2.84Å; Y148-Q154 PolarHBondContact O-NE2 2.74Å; N150-Q154 VanDerWaalsContact O-CG 3.27Å; N150-Q154 WeakPolarHBondContact O-CG 3.38Å; N150-Q154 PolarHBondContact O-N 3.01Å; F152-Q154 VanDerWaalsContact C-N 3.33Å; F152-Q154 PolarHBondContact O-N 2.81Å; Q154-L157 PolarHBondContact O-N 3.3Å; Q154-N158 WeakPolarHBondContact O-CB 3.24Å; Q154-N158 PolarHBondContact O-N 3.07Å; Q154-K397 HydrophobicContact CB-CB 4.33Å; Q154-K397 HydrophobicContact CB-CD 4.4Å
155L94.6Very high94.3Very high96 Ų9665.2 Ų65.250%0.50334%0.342SS..Hα-helixtrans-67.2-39.9175.7-176.365.7000112.1A151 F152 I153 T159A151-L155 PolarHBondContact O-N 3.04Å; F152-L155 WeakPolarHBondContact O-CB 3.3Å; F152-L155 PolarHBondContact O-N 2.84Å; I153-L155 VanDerWaalsContact C-N 3.27Å; I153-L155 PolarHBondContact O-N 3.02Å; L155-T159 PolarHBondContact O-N 3.19Å; L155-T159 PolarHBondContact O-OG1 2.88Å
156L95.2Very high94.5Very high45 Ų4565.3 Ų65.324%0.23634%0.343CS..Hα-helixtrans-65.8-45174.1-64.9-179.7000111.7F152 I153 N158 T159 W160F152-L156 HydrophobicContact CD1-CD1 4.16Å; F152-L156 HydrophobicContact CE1-CD1 3.62Å; F152-L156 HydrophobicContact CE1-CG 4.26Å; F152-L156 HydrophobicContact CZ-CD1 4.06Å; F152-L156 HydrophobicContact CZ-CD2 4.44Å; F152-L156 HydrophobicContact CZ-CG 4.36Å; F152-L156 PolarHBondContact O-N 3.37Å; I153-L156 HydrophobicContact CD1-CD1 4.41Å; I153-L156 WeakPolarHBondContact O-CB 3.37Å; I153-L156 PolarHBondContact O-N 3.27Å; L156-N158 VanDerWaalsContact C-N 3.33Å; L156-N158 PolarHBondContact O-N 3.42Å; L156-T159 WeakPolarHBondContact O-CB 3.37Å; L156-T159 PolarHBondContact O-N 3.33Å; L156-W160 HydrophobicContact CB-CE3 4.3Å; L156-W160 HydrophobicContact CB-CH2 3.7Å; L156-W160 HydrophobicContact CB-CZ2 3.95Å; L156-W160 HydrophobicContact CB-CZ3 3.88Å; L156-W160 HydrophobicContact CD1-CH2 4.06Å; L156-W160 HydrophobicContact CD1-CZ2 4.31Å; L156-W160 HydrophobicContact CG-CH2 4.47Å; L156-W160 VanDerWaalsContact O-CD2 3.3Å; L156-W160 PolarHBondContact O-N 3.04Å
157L95.6Very high94.7Very high3 Ų366.9 Ų66.92%0.01635%0.349CS..Hα-helixtrans-56-48.6175.5-66.4174.9000110.8A144 I153 Q154 T159 W160 M161 F185 I398A144-L157 HydrophobicContact CB-CD1 4.45Å; A144-L157 HydrophobicContact CB-CD2 4.29Å; I153-L157 HydrophobicContact CG2-CD1 4.11Å; I153-L157 HydrophobicContact CG2-CG 4.06Å; I153-L157 VanDerWaalsContact O-CG 3.3Å; I153-L157 WeakPolarHBondContact O-CG 3.08Å; I153-L157 PolarHBondContact O-N 3.03Å; Q154-L157 PolarHBondContact O-N 3.3Å; L157-T159 VanDerWaalsContact C-N 3.29Å; L157-T159 PolarHBondContact O-N 2.89Å; L157-W160 HydrophobicContact CD2-CE3 4.07Å; L157-W160 HydrophobicContact CD2-CZ3 4.05Å; L157-W160 PolarHBondContact O-N 3.22Å; L157-M161 HydrophobicContact CB-CE 4.32Å; L157-M161 WeakPolarHBondContact O-CB 3.16Å; L157-M161 VanDerWaalsContact O-CG 3.24Å; L157-M161 WeakPolarHBondContact O-CG 3.45Å; L157-M161 PolarHBondContact O-N 3.07Å; L157-F185 HydrophobicContact CD2-CE2 4.03Å; L157-F185 HydrophobicContact CD2-CZ 3.74Å; L157-I398 HydrophobicContact CB-CD1 4.36Å
158N96.8Very high95Very high18 Ų1864 Ų6410%0.09633%0.334CS..Hα-helixtrans-56.8-42.2175.1-17345.3000112.1Q154 L156 M161 K162 K397 I398 E399Q154-N158 WeakPolarHBondContact O-CB 3.24Å; Q154-N158 PolarHBondContact O-N 3.07Å; L156-N158 VanDerWaalsContact C-N 3.33Å; L156-N158 PolarHBondContact O-N 3.42Å; N158-M161 PolarHBondContact O-N 3.49Å; N158-K162 WeakPolarHBondContact ND2-CE 3.22Å; N158-K162 WeakPolarHBondContact O-CB 3.48Å; N158-K162 VanDerWaalsContact O-CG 3.29Å; N158-K162 WeakPolarHBondContact O-CG 3.49Å; N158-K162 PolarHBondContact O-N 3.17Å; N158-K397 WeakPolarHBondContact CB-O 3.23Å; N158-K397 PolarHBondContact ND2-O 3.02Å; N158-I398 HydrophobicContact CB-CG1 4.19Å; N158-I398 WeakPolarHBondContact OD1-CA 3.39Å; N158-E399 PolarHBondContact OD1-N 3.36Å
159T96.6Very high95.3Very high74 Ų7458.5 Ų58.545%0.45431%0.313SS..Hα-helixtrans-64.3-44.3179-57.90000111.7L155 L156 L157 K162 S163L155-T159 PolarHBondContact O-N 3.19Å; L155-T159 PolarHBondContact O-OG1 2.88Å; L156-T159 WeakPolarHBondContact O-CB 3.37Å; L156-T159 PolarHBondContact O-N 3.33Å; L157-T159 VanDerWaalsContact C-N 3.29Å; L157-T159 PolarHBondContact O-N 2.89Å; T159-K162 PolarHBondContact O-N 2.87Å; T159-S163 WeakPolarHBondContact O-CB 3.28Å; T159-S163 PolarHBondContact O-N 2.94Å
160W96.8Very high95.7Very high41 Ų4153.9 Ų53.916%0.15528%0.283CS..Hα-helixtrans-67.8-40.7177.2-61.9-40.1000112.5L156 L157 K162 S163 S164 F185 K188 I189 P190 F191L156-W160 HydrophobicContact CB-CE3 4.3Å; L156-W160 HydrophobicContact CB-CH2 3.7Å; L156-W160 HydrophobicContact CB-CZ2 3.95Å; L156-W160 HydrophobicContact CB-CZ3 3.88Å; L156-W160 HydrophobicContact CD1-CH2 4.06Å; L156-W160 HydrophobicContact CD1-CZ2 4.31Å; L156-W160 HydrophobicContact CG-CH2 4.47Å; L156-W160 VanDerWaalsContact O-CD2 3.3Å; L156-W160 PolarHBondContact O-N 3.04Å; L157-W160 HydrophobicContact CD2-CE3 4.07Å; L157-W160 HydrophobicContact CD2-CZ3 4.05Å; L157-W160 PolarHBondContact O-N 3.22Å; W160-K162 PolarHBondContact O-N 2.9Å; W160-S163 PolarHBondContact O-N 3.21Å; W160-S164 PolarHBondContact O-N 3.28Å; W160-S164 PolarHBondContact O-OG 2.91Å; W160-S164 VanDerWaalsContact O-OG 3.1Å; W160-F185 HydrophobicContact CB-CD2 3.97Å; W160-F185 HydrophobicContact CB-CE2 4.1Å; W160-K188 HydrophobicContact CB-CB 4.07Å; W160-K188 HydrophobicContact CG-CB 4.32Å; W160-I189 HydrophobicContact CD2-CG1 4.25Å; W160-I189 HydrophobicContact CE3-CD1 4.35Å; W160-I189 HydrophobicContact CE3-CG1 3.73Å; W160-I189 HydrophobicContact CH2-CG2 4.38Å; W160-I189 HydrophobicContact CZ3-CG1 4.08Å; W160-I189 HydrophobicContact CZ3-CG2 4.18Å; W160-P190 HydrophobicContact CH2-CG 4.46Å; W160-P190 HydrophobicContact CZ2-CG 3.8Å; W160-F191 HydrophobicContact CH2-CE2 4.12Å
161M97.6Very high96Very high2 Ų254.5 Ų54.51%0.0129%0.286CS..Hα-helixtrans-60.6-42.5174.4-70.3175.7-171.200111.9V141 P145 L157 N158 S164 K165 S166 F185 I398V141-M161 HydrophobicContact CB-CE 4.37Å; V141-M161 HydrophobicContact CB-SD 4.49Å; V141-M161 HydrophobicContact CG1-CE 4.34Å; V141-M161 HydrophobicContact CG1-SD 4.06Å; V141-M161 HydrophobicContact CG2-CE 4.36Å; V141-M161 HydrophobicContact CG2-CG 4.35Å; V141-M161 HydrophobicContact CG2-SD 4.21Å; P145-M161 HydrophobicContact CG-CE 4.06Å; L157-M161 HydrophobicContact CB-CE 4.32Å; L157-M161 WeakPolarHBondContact O-CB 3.16Å; L157-M161 VanDerWaalsContact O-CG 3.24Å; L157-M161 WeakPolarHBondContact O-CG 3.45Å; L157-M161 PolarHBondContact O-N 3.07Å; N158-M161 PolarHBondContact O-N 3.49Å; M161-S164 PolarHBondContact O-N 3.42Å; M161-S164 PolarHBondContact O-OG 3.04Å; M161-S164 VanDerWaalsContact O-OG 3.09Å; M161-K165 PolarHBondContact O-N 2.87Å; M161-S166 PolarHBondContact O-N 2.76Å; M161-F185 HydrophobicContact CB-CD2 4.43Å; M161-F185 HydrophobicContact CE-CD1 4.17Å; M161-F185 HydrophobicContact CE-CD2 4.46Å; M161-F185 HydrophobicContact CE-CE1 3.6Å; M161-F185 HydrophobicContact CE-CE2 3.94Å; M161-F185 HydrophobicContact CE-CZ 3.49Å; M161-F185 VanDerWaalsContact CE-CZ 3.49Å; M161-F185 HydrophobicContact CG-CB 4.41Å; M161-F185 HydrophobicContact CG-CD1 4.24Å; M161-F185 HydrophobicContact CG-CD2 3.52Å; M161-F185 HydrophobicContact CG-CE1 4.45Å; M161-F185 HydrophobicContact CG-CE2 3.77Å; M161-F185 HydrophobicContact CG-CG 3.79Å; M161-F185 HydrophobicContact CG-CZ 4.24Å; M161-I398 HydrophobicContact CE-CD1 4.36Å; M161-I398 HydrophobicContact SD-CG2 3.59Å; M161-I398 VanDerWaalsContact SD-CG2 3.59Å
162K96.8Very high96.3Very high109 Ų10953.7 Ų53.747%0.47427%0.272SS..Hα-helixtrans-62-45.1173.7-74.3178.4-178.2-1510111.9N158 T159 W160 S164 K165 E399N158-K162 WeakPolarHBondContact ND2-CE 3.22Å; N158-K162 WeakPolarHBondContact O-CB 3.48Å; N158-K162 VanDerWaalsContact O-CG 3.29Å; N158-K162 WeakPolarHBondContact O-CG 3.49Å; N158-K162 PolarHBondContact O-N 3.17Å; T159-K162 PolarHBondContact O-N 2.87Å; W160-K162 PolarHBondContact O-N 2.9Å; K162-S164 VanDerWaalsContact C-N 3.3Å; K162-S164 PolarHBondContact O-N 2.8Å; K162-K165 PolarHBondContact O-N 2.96Å; K162-K165 VanDerWaalsContact O-N 3.12Å; K162-E399 WeakPolarHBondContact CE-OE2 3.45Å; K162-E399 IonicContact NZ-OE2 3.39Å; K162-E399 PolarHBondContact NZ-OE2 2.86Å
163S96.4Very high96.6Very high75 Ų7548.6 Ų48.652%0.52425%0.252SS..Hα-helixtrans-62-36.8179-1760000112.7T159 W160 K165T159-S163 WeakPolarHBondContact O-CB 3.28Å; T159-S163 PolarHBondContact O-N 2.94Å; W160-S163 PolarHBondContact O-N 3.21Å; S163-K165 VanDerWaalsContact C-N 3.35Å
164S96.8Very high96.9Very high21 Ų2146.2 Ų46.215%0.14724%0.24CC..Hα-helixtrans-86.4-2.9176.3630000114.1W160 M161 K162 S166 P184 F185W160-S164 PolarHBondContact O-N 3.28Å; W160-S164 PolarHBondContact O-OG 2.91Å; W160-S164 VanDerWaalsContact O-OG 3.1Å; M161-S164 PolarHBondContact O-N 3.42Å; M161-S164 PolarHBondContact O-OG 3.04Å; M161-S164 VanDerWaalsContact O-OG 3.09Å; K162-S164 VanDerWaalsContact C-N 3.3Å; K162-S164 PolarHBondContact O-N 2.8Å; S164-S166 PolarHBondContact O-N 2.82Å; S164-S166 WeakPolarHBondContact OG-CB 3.35Å; S164-S166 PolarHBondContact OG-OG 3.24Å; S164-P184 WeakPolarHBondContact CB-O 3.44Å; S164-F185 WeakPolarHBondContact OG-CA 3.11Å; S164-F185 WeakPolarHBondContact OG-CB 3.41Å
165K96.7Very high97.1Very high184 Ų18450.2 Ų50.280%0.826%0.257SS*.THydrogen-bonded Turntrans55.433.3-172.4-54.1178.8-179.8-179.90112.8M161 K162 S163M161-K165 PolarHBondContact O-N 2.87Å; K162-K165 PolarHBondContact O-N 2.96Å; K162-K165 VanDerWaalsContact O-N 3.12Å; S163-K165 VanDerWaalsContact C-N 3.35Å
166S97.4Very high97.3Very high13 Ų1348.3 Ų48.39%0.09125%0.245CC..  trans-83.1125.9179.7-62.60000110.4M161 S164 F185M161-S166 PolarHBondContact O-N 2.76Å; S164-S166 PolarHBondContact O-N 2.82Å; S164-S166 WeakPolarHBondContact OG-CB 3.35Å; S164-S166 PolarHBondContact OG-OG 3.24Å; S166-F185 WeakPolarHBondContact OG-CB 3.35Å
167V96.8Very high97.4Very high67 Ų6746.2 Ų46.241%0.40624%0.235SC..  trans-117.8174.4175.7-57.20000110.5L77 N138 L169L77-V167 HydrophobicContact CD1-CG2 4.18Å; L77-V167 HydrophobicContact CD2-CB 4.4Å; L77-V167 HydrophobicContact CD2-CG2 4.35Å; N138-V167 WeakPolarHBondContact CB-O 3.26Å; N138-V167 PolarHBondContact ND2-O 3.08Å; V167-L169 VanDerWaalsContact C-N 3.29Å; V167-L169 WeakPolarHBondContact CG2-O 3.35Å; V167-L169 PolarHBondContact O-N 2.64Å
168M96.8Very high97.6Very high7 Ų746 Ų463%0.03423%0.234CC..SBendtrans-62.5-31.4-174.3175.7174.7176.300114.2L77 L137 N138 V392 A400 L401 V404 Y408L77-M168 HydrophobicContact CD2-CB 3.91Å; L137-M168 HydrophobicContact CD1-CE 3.8Å; L137-M168 HydrophobicContact CD1-CG 3.92Å; N138-M168 WeakPolarHBondContact CB-O 3.19Å; N138-M168 PolarHBondContact N-O 3.35Å; M168-V392 HydrophobicContact CE-CB 4.41Å; M168-V392 HydrophobicContact CE-CG1 3.54Å; M168-V392 HydrophobicContact CE-CG2 4.06Å; M168-A400 WeakPolarHBondContact CB-O 3.41Å; M168-L401 HydrophobicContact CB-CD2 4.07Å; M168-L401 HydrophobicContact CG-CD2 3.92Å; M168-L401 HydrophobicContact SD-CD2 3.86Å; M168-V404 HydrophobicContact CE-CG2 4.02Å; M168-V404 HydrophobicContact SD-CG2 3.72Å; M168-Y408 WeakPolarHBondContact CE-OH 3.34Å
169L98.1Very high97.6Very high10 Ų1047.2 Ų47.25%0.05224%0.237CC..EExtended strand (participates in β ladder)trans-110.7151.2175.6-59.4-179.2000110V70 P73 V76 L77 C136 L137 V167V70-L169 HydrophobicContact CB-CD1 4.49Å; V70-L169 HydrophobicContact CG1-CD1 3.94Å; V70-L169 HydrophobicContact CG2-CD2 4.29Å; P73-L169 HydrophobicContact CB-CD1 3.76Å; V76-L169 HydrophobicContact CB-CD1 4.01Å; V76-L169 HydrophobicContact CG1-CD1 3.99Å; L77-L169 HydrophobicContact CD1-CB 4.39Å; L77-L169 HydrophobicContact CD2-CB 4.26Å; L77-L169 HydrophobicContact CD2-CD1 4.48Å; L77-L169 HydrophobicContact CD2-CG 4.11Å; L77-L169 HydrophobicContact CG-CB 4.49Å; L77-L169 HydrophobicContact CG-CD1 4.21Å; L77-L169 HydrophobicContact CG-CG 4.35Å; C136-L169 CarbonylContact O-C 3.58Å; C136-L169 WeakPolarHBondContact O-CA 3.2Å; L137-L169 HydrophobicContact CD1-CD2 4.16Å; V167-L169 VanDerWaalsContact C-N 3.29Å; V167-L169 WeakPolarHBondContact CG2-O 3.35Å; V167-L169 PolarHBondContact O-N 2.64Å
170Q97.8Very high97.7Very high20 Ų2044.8 Ų44.89%0.09323%0.227CC..EExtended strand (participates in β ladder)trans-148.1158.1-179.560.4173.8-15.800111.1T135 C136 L137 N138 R172 Y181T135-Q170 WeakPolarHBondContact CA-O 3.46Å; C136-Q170 PolarHBondContact N-O 3.46Å; C136-Q170 PolarHBondContact O-N 3.09Å; L137-Q170 PolarHBondContact O-NE2 3.01Å; N138-Q170 HydrophobicContact CB-CB 4.41Å; N138-Q170 HydrophobicContact CB-CG 4.05Å; Q170-R172 HydrophobicContact CG-CG 4.03Å; Q170-Y181 PolarHBondContact NE2-OH 3.08Å
171N98.3Very high97.8Very high105 Ų10543.3 Ų43.356%0.56122%0.221SC*.EExtended strand (participates in β ladder)trans-96.3125.9171.2-65-1.5000108.6T133 I134 T135T133-N171 HydrophobicContact CG2-CB 3.85Å; I134-N171 WeakPolarHBondContact O-CA 3.47Å; T135-N171 PolarHBondContact OG1-OD1 3.46Å
172R98.3Very high97.8Very high35 Ų3549.9 Ų49.913%0.13225%0.249CC..EExtended strand (participates in β ladder)trans-137.8152176.9-69.4-64175.1-176.4-2.8110.4T133 I134 Q170 E176 I177 Y181T133-R172 WeakPolarHBondContact CA-O 3.22Å; I134-R172 PolarHBondContact N-O 3.4Å; I134-R172 PolarHBondContact O-N 2.02Å; Q170-R172 HydrophobicContact CG-CG 4.03Å; R172-E176 WeakPolarHBondContact CA-OE2 3.48Å; R172-E176 HydrophobicContact CB-CB 4.25Å; R172-E176 VanDerWaalsContact CD-OE2 3.24Å; R172-E176 WeakPolarHBondContact CD-OE2 3.11Å; R172-E176 IonicContact NH1-OE1 3.79Å; R172-E176 PolarHBondContact NH1-OE1 2.84Å; R172-E176 IonicContact NH1-OE2 2.79Å; R172-I177 HydrophobicContact CB-CB 4.42Å; R172-Y181 HydrophobicContact CG-CE1 4.37Å; R172-Y181 VanDerWaalsContact CZ-CE2 3.41Å; R172-Y181 VanDerWaalsContact NH2-CD2 3.31Å; R172-Y181 VanDerWaalsContact NH2-CE2 3.29Å
173T98.7Very high97.8Very high28 Ų2844.7 Ų44.717%0.17223%0.227CC..EExtended strand (participates in β ladder)trans-73.4158.4168.872.90000110.8E130 D132 K175 E176 I177E130-T173 WeakPolarHBondContact O-CB 3.4Å; D132-T173 CarbonylContact O-C 3.52Å; D132-T173 WeakPolarHBondContact O-CA 3.46Å; T173-K175 PolarHBondContact O-N 3.14Å; T173-E176 PolarHBondContact N-OE2 3.1Å; T173-E176 PolarHBondContact O-N 3.11Å; T173-E176 VanDerWaalsContact O-N 3.16Å; T173-E176 WeakPolarHBondContact OG1-CG 3.44Å; T173-E176 PolarHBondContact OG1-N 2.82Å; T173-I177 WeakPolarHBondContact O-CG2 3.27Å; T173-I177 PolarHBondContact O-N 2.89Å
174V98.6Very high97.9Very high0 Ų043.7 Ų43.70%022%0.219CC..Hα-helixtrans-52.7-42.8171.9173.10000111I67 Y91 E130 D132 I134 I177 L178I67-V174 HydrophobicContact CD1-CB 4.35Å; I67-V174 HydrophobicContact CD1-CG1 4.02Å; I67-V174 HydrophobicContact CD1-CG2 4.06Å; Y91-V174 HydrophobicContact CD1-CB 4.49Å; Y91-V174 HydrophobicContact CD1-CG1 3.95Å; Y91-V174 HydrophobicContact CD1-CG2 4.1Å; Y91-V174 HydrophobicContact CD2-CG1 4.03Å; Y91-V174 HydrophobicContact CD2-CG2 4.02Å; Y91-V174 HydrophobicContact CE1-CB 4.47Å; Y91-V174 HydrophobicContact CE1-CG1 4.4Å; Y91-V174 HydrophobicContact CE1-CG2 3.7Å; Y91-V174 HydrophobicContact CE2-CG1 4.46Å; Y91-V174 HydrophobicContact CE2-CG2 3.59Å; Y91-V174 HydrophobicContact CG-CG1 3.76Å; Y91-V174 HydrophobicContact CG-CG2 4.26Å; Y91-V174 VanDerWaalsContact CZ-CG2 3.43Å; E130-V174 PolarHBondContact O-N 3.28Å; D132-V174 HydrophobicContact CB-CG2 4.05Å; D132-V174 PolarHBondContact O-N 2.98Å; I134-V174 HydrophobicContact CD1-CG2 3.83Å; I134-V174 HydrophobicContact CG1-CG2 4.48Å; V174-I177 WeakPolarHBondContact O-CG2 3.31Å; V174-L178 HydrophobicContact CG1-CD1 3.7Å; V174-L178 HydrophobicContact CG1-CG 4.39Å; V174-L178 WeakPolarHBondContact O-CB 3.41Å; V174-L178 VanDerWaalsContact O-CG 3.27Å; V174-L178 WeakPolarHBondContact O-CG 3.25Å; V174-L178 PolarHBondContact O-N 2.78Å; V174-L178 VanDerWaalsContact O-N 3.11Å
175K98.4Very high97.9Very high101 Ų10142.7 Ų42.744%0.43921%0.212SC..Hα-helixtrans-60-48.3177.4-161.5171.1-174.1149.90112.5E130 T173 W179E130-K175 HydrophobicContact CB-CB 4.09Å; E130-K175 HydrophobicContact CB-CD 4.49Å; E130-K175 WeakPolarHBondContact O-CB 3.32Å; E130-K175 PolarHBondContact O-N 2.98Å; E130-K175 IonicContact OE2-NZ 3.02Å; E130-K175 PolarHBondContact OE2-NZ 3.48Å; T173-K175 PolarHBondContact O-N 3.14Å; K175-W179 WeakPolarHBondContact O-CB 3.4Å; K175-W179 PolarHBondContact O-N 2.88Å
176E98.6Very high97.8Very high56 Ų5635 Ų3526%0.26218%0.179SC..Hα-helixtrans-61.5-51.6-178.2-77.4-177.4124.300110.5R172 T173 L178 G180 Y181R172-E176 WeakPolarHBondContact CA-OE2 3.48Å; R172-E176 HydrophobicContact CB-CB 4.25Å; R172-E176 VanDerWaalsContact CD-OE2 3.24Å; R172-E176 WeakPolarHBondContact CD-OE2 3.11Å; R172-E176 IonicContact NH1-OE1 3.79Å; R172-E176 PolarHBondContact NH1-OE1 2.84Å; R172-E176 IonicContact NH1-OE2 2.79Å; T173-E176 PolarHBondContact N-OE2 3.1Å; T173-E176 PolarHBondContact O-N 3.11Å; T173-E176 VanDerWaalsContact O-N 3.16Å; T173-E176 WeakPolarHBondContact OG1-CG 3.44Å; T173-E176 PolarHBondContact OG1-N 2.82Å; E176-L178 PolarHBondContact O-N 2.92Å; E176-G180 CarbonylContact O-C 3.39Å; E176-G180 VanDerWaalsContact O-C 3.25Å; E176-G180 VanDerWaalsContact O-CA 3.3Å; E176-G180 WeakPolarHBondContact O-CA 3.44Å; E176-G180 PolarHBondContact O-N 2.83Å; E176-Y181 HydrophobicContact CB-CD1 4.07Å; E176-Y181 HydrophobicContact CB-CG 4.29Å; E176-Y181 WeakPolarHBondContact O-CD1 3.31Å
177I98.3Very high97.7Very high1 Ų136.9 Ų36.91%0.00519%0.192CC..Hα-helixtrans-67.3-35.9-174.9-167.559.9000112.4I67 L139 R172 T173 V174 G198 V199I67-I177 HydrophobicContact CD1-CG2 3.87Å; L139-I177 HydrophobicContact CD1-CD1 3.74Å; L139-I177 HydrophobicContact CG-CD1 4.1Å; R172-I177 HydrophobicContact CB-CB 4.42Å; T173-I177 WeakPolarHBondContact O-CG2 3.27Å; T173-I177 PolarHBondContact O-N 2.89Å; V174-I177 WeakPolarHBondContact O-CG2 3.31Å; I177-G198 WeakPolarHBondContact O-CA 3.16Å; I177-V199 HydrophobicContact CD1-CG2 4.47Å; I177-V199 HydrophobicContact CG1-CG2 4.3Å; I177-V199 PolarHBondContact O-N 3.21Å
178L98.5Very high97.6Very high0 Ų038.7 Ų38.70%020%0.195CC..Hα-helixtrans-75.2-54.7178.2-67.4177.2000112F65 Y93 V174 E176 F200 L413F65-L178 HydrophobicContact CB-CD2 4.46Å; F65-L178 HydrophobicContact CD1-CD2 3.97Å; F65-L178 HydrophobicContact CD2-CD1 3.72Å; F65-L178 HydrophobicContact CD2-CD2 4.2Å; F65-L178 HydrophobicContact CE1-CD2 4.2Å; F65-L178 HydrophobicContact CE2-CD1 4.06Å; F65-L178 HydrophobicContact CE2-CD2 4.4Å; F65-L178 HydrophobicContact CG-CD1 4.16Å; F65-L178 HydrophobicContact CG-CD2 3.96Å; F65-L178 HydrophobicContact CZ-CD2 4.37Å; Y93-L178 HydrophobicContact CE2-CD1 3.87Å; V174-L178 HydrophobicContact CG1-CD1 3.7Å; V174-L178 HydrophobicContact CG1-CG 4.39Å; V174-L178 WeakPolarHBondContact O-CB 3.41Å; V174-L178 VanDerWaalsContact O-CG 3.27Å; V174-L178 WeakPolarHBondContact O-CG 3.25Å; V174-L178 PolarHBondContact O-N 2.78Å; V174-L178 VanDerWaalsContact O-N 3.11Å; E176-L178 PolarHBondContact O-N 2.92Å; L178-F200 HydrophobicContact CD2-CD2 3.94Å; L178-F200 HydrophobicContact CD2-CE2 3.8Å; L178-F200 WeakPolarHBondContact O-CA 3.23Å; L178-F200 WeakPolarHBondContact O-CB 3.21Å; L178-F200 PolarHBondContact O-N 3.24Å; L178-L413 HydrophobicContact CD2-CD2 3.49Å; L178-L413 VanDerWaalsContact CD2-CD2 3.49Å
179W98.2Very high97.4Very high43 Ų4340 Ų4016%0.16320%0.201CC..Hα-helixtrans-105.8-12.6-162.9-51122.1000114.5F65 Y93 A119 K175 F200 Y201 Y203F65-W179 HydrophobicContact CE2-CH2 4.18Å; F65-W179 HydrophobicContact CE2-CZ2 4.11Å; F65-W179 HydrophobicContact CZ-CH2 4.2Å; Y93-W179 AromaticContact CD1-CZ2 3.74Å; Y93-W179 HydrophobicContact CD1-CZ2 3.74Å; Y93-W179 HydrophobicContact CD2-CZ2 4.2Å; Y93-W179 AromaticContact CE1-CE2 3.72Å; Y93-W179 AromaticContact CE1-CZ2 3.55Å; Y93-W179 HydrophobicContact CE1-CZ2 3.55Å; Y93-W179 AromaticContact CE1-NE1 3.36Å; Y93-W179 HydrophobicContact CE2-CZ2 4.06Å; Y93-W179 HydrophobicContact CG-CZ2 4.05Å; Y93-W179 AromaticContact CZ-CE2 3.83Å; Y93-W179 AromaticContact CZ-CZ2 3.72Å; Y93-W179 AromaticContact CZ-NE1 3.33Å; Y93-W179 VanDerWaalsContact CZ-NE1 3.33Å; Y93-W179 PolarHBondContact OH-NE1 3.22Å; A119-W179 HydrophobicContact CB-CH2 3.61Å; A119-W179 HydrophobicContact CB-CZ2 3.82Å; A119-W179 HydrophobicContact CB-CZ3 4.35Å; K175-W179 WeakPolarHBondContact O-CB 3.4Å; K175-W179 PolarHBondContact O-N 2.88Å; W179-F200 HydrophobicContact CE3-CB 3.98Å; W179-F200 HydrophobicContact CZ3-CB 3.74Å; W179-F200 HydrophobicContact CZ3-CD2 4.47Å; W179-F200 HydrophobicContact CZ3-CG 4.26Å; W179-Y201 VanDerWaalsContact O-CD2 3.24Å; W179-Y201 WeakPolarHBondContact O-CD2 3.5Å; W179-Y203 HydrophobicContact CE3-CD1 4.35Å; W179-Y203 HydrophobicContact CE3-CG 4.26Å; W179-Y203 HydrophobicContact CH2-CD1 4.16Å; W179-Y203 AromaticContact CZ3-CD1 3.58Å; W179-Y203 HydrophobicContact CZ3-CD1 3.58Å; W179-Y203 HydrophobicContact CZ3-CD2 4.41Å; W179-Y203 HydrophobicContact CZ3-CE1 4.29Å; W179-Y203 AromaticContact CZ3-CG 3.65Å; W179-Y203 HydrophobicContact CZ3-CG 3.65Å
180G97.8Very high96.9Very high23 Ų2343.9 Ų43.924%0.23723%0.228CC..  trans127.3143.3171.400000113.9E176 L197E176-G180 CarbonylContact O-C 3.39Å; E176-G180 VanDerWaalsContact O-C 3.25Å; E176-G180 VanDerWaalsContact O-CA 3.3Å; E176-G180 WeakPolarHBondContact O-CA 3.44Å; E176-G180 PolarHBondContact O-N 2.83Å; G180-L197 CarbonylContact C-O 3.55Å; G180-L197 VanDerWaalsContact CA-O 3.23Å; G180-L197 WeakPolarHBondContact CA-O 3.39Å
181Y98.3Very high96.3Very high9 Ų949.3 Ų49.34%0.03525%0.251CS..EExtended strand (participates in β ladder)trans-138.8155.5168.263.1-83.6000109.8Q170 R172 E176 D183 V196 L197Q170-Y181 PolarHBondContact NE2-OH 3.08Å; R172-Y181 HydrophobicContact CG-CE1 4.37Å; R172-Y181 VanDerWaalsContact CZ-CE2 3.41Å; R172-Y181 VanDerWaalsContact NH2-CD2 3.31Å; R172-Y181 VanDerWaalsContact NH2-CE2 3.29Å; E176-Y181 HydrophobicContact CB-CD1 4.07Å; E176-Y181 HydrophobicContact CB-CG 4.29Å; E176-Y181 WeakPolarHBondContact O-CD1 3.31Å; Y181-D183 HydrophobicContact CD2-CB 4.41Å; Y181-D183 HydrophobicContact CE2-CB 3.89Å; Y181-D183 PolarHBondContact O-N 2.96Å; Y181-V196 VanDerWaalsContact O-CA 3.29Å; Y181-V196 WeakPolarHBondContact O-CA 3.08Å; Y181-L197 WeakPolarHBondContact CD1-O 3.14Å; Y181-L197 HydrophobicContact CE1-CD1 3.8Å; Y181-L197 HydrophobicContact CE1-CG 4.3Å; Y181-L197 HydrophobicContact CE2-CG 4.47Å; Y181-L197 PolarHBondContact N-O 3.35Å; Y181-L197 PolarHBondContact O-N 2.94Å; Y181-L197 WeakPolarHBondContact OH-CD1 3.41Å
182K97.9Very high95.8Very high140 Ų14051.1 Ų51.161%0.60927%0.268SS*.EExtended strand (participates in β ladder)trans-77.2112.3172.5-175.6172.3-178.71770109.2S187 P195 V196K182-S187 WeakPolarHBondContact CE-OG 3.35Å; K182-S187 WeakPolarHBondContact CG-OG 3.26Å; K182-P195 HydrophobicContact CD-CG 4.36Å; K182-P195 HydrophobicContact CG-CB 4.14Å; K182-P195 HydrophobicContact CG-CG 4.01Å; K182-V196 HydrophobicContact CB-CG2 4.46Å
183D98Very high95.3Very high0 Ų053.3 Ų53.30%028%0.282CS..  trans-75.5128.3-178.8-179-99000111.5A140 Y181 F185 L186 S187 P195 L197A140-D183 HydrophobicContact CB-CB 4.37Å; Y181-D183 HydrophobicContact CD2-CB 4.41Å; Y181-D183 HydrophobicContact CE2-CB 3.89Å; Y181-D183 PolarHBondContact O-N 2.96Å; D183-F185 VanDerWaalsContact C-N 3.31Å; D183-F185 PolarHBondContact O-N 2.82Å; D183-F185 VanDerWaalsContact OD1-CA 3.31Å; D183-F185 WeakPolarHBondContact OD1-CA 3.24Å; D183-F185 WeakPolarHBondContact OD1-CB 3.24Å; D183-F185 PolarHBondContact OD1-N 2.82Å; D183-L186 HydrophobicContact CB-CB 4.12Å; D183-L186 HydrophobicContact CB-CD1 4.26Å; D183-L186 HydrophobicContact CB-CG 3.98Å; D183-L186 PolarHBondContact OD1-N 2.8Å; D183-S187 WeakPolarHBondContact O-CB 3.03Å; D183-S187 PolarHBondContact O-N 3.37Å; D183-S187 PolarHBondContact O-OG 3.41Å; D183-P195 PolarHBondContact N-O 2.58Å; D183-L197 HydrophobicContact CB-CD2 3.62Å; D183-L197 HydrophobicContact CB-CG 4.5Å
184P96.8Very high95Very high54 Ų5456 Ų5635%0.35130%0.295SS..THydrogen-bonded Turntrans-61.9-34.2179.3-2635.4000114.1S164 K188S164-P184 WeakPolarHBondContact CB-O 3.44Å; P184-K188 WeakPolarHBondContact O-CG 3.37Å
185F96.6Very high94.9Very high0 Ų057.2 Ų57.20%030%0.303CS..THydrogen-bonded Turntrans-73.9-48.9179.6146.1-119.2000110.7A140 V141 A144 L157 W160 M161 S164 S166 D183 S187 K188 I189A140-F185 HydrophobicContact CB-CD1 3.67Å; A140-F185 HydrophobicContact CB-CE1 3.97Å; V141-F185 HydrophobicContact CG2-CD1 4.41Å; A144-F185 HydrophobicContact CB-CE1 3.83Å; A144-F185 HydrophobicContact CB-CZ 3.84Å; L157-F185 HydrophobicContact CD2-CE2 4.03Å; L157-F185 HydrophobicContact CD2-CZ 3.74Å; W160-F185 HydrophobicContact CB-CD2 3.97Å; W160-F185 HydrophobicContact CB-CE2 4.1Å; M161-F185 HydrophobicContact CB-CD2 4.43Å; M161-F185 HydrophobicContact CE-CD1 4.17Å; M161-F185 HydrophobicContact CE-CD2 4.46Å; M161-F185 HydrophobicContact CE-CE1 3.6Å; M161-F185 HydrophobicContact CE-CE2 3.94Å; M161-F185 HydrophobicContact CE-CZ 3.49Å; M161-F185 VanDerWaalsContact CE-CZ 3.49Å; M161-F185 HydrophobicContact CG-CB 4.41Å; M161-F185 HydrophobicContact CG-CD1 4.24Å; M161-F185 HydrophobicContact CG-CD2 3.52Å; M161-F185 HydrophobicContact CG-CE1 4.45Å; M161-F185 HydrophobicContact CG-CE2 3.77Å; M161-F185 HydrophobicContact CG-CG 3.79Å; M161-F185 HydrophobicContact CG-CZ 4.24Å; S164-F185 WeakPolarHBondContact OG-CA 3.11Å; S164-F185 WeakPolarHBondContact OG-CB 3.41Å; S166-F185 WeakPolarHBondContact OG-CB 3.35Å; D183-F185 VanDerWaalsContact C-N 3.31Å; D183-F185 PolarHBondContact O-N 2.82Å; D183-F185 VanDerWaalsContact OD1-CA 3.31Å; D183-F185 WeakPolarHBondContact OD1-CA 3.24Å; D183-F185 WeakPolarHBondContact OD1-CB 3.24Å; D183-F185 PolarHBondContact OD1-N 2.82Å; F185-S187 PolarHBondContact O-N 2.7Å; F185-K188 WeakPolarHBondContact O-CB 3.45Å; F185-K188 PolarHBondContact O-N 3.13Å; F185-I189 HydrophobicContact CE2-CD1 4.05Å; F185-I189 HydrophobicContact CE2-CG1 4.35Å; F185-I189 HydrophobicContact CZ-CD1 4.06Å
186L95.9Very high94.8Very high24 Ų2454.4 Ų54.413%0.12630%0.295CS..G310 helixtrans-60.4-32.8176.7-62.7-168.2000112A140 D183 K188 I189 L193 P195 L197A140-L186 HydrophobicContact CB-CD1 4.18Å; A140-L186 HydrophobicContact CB-CD2 3.97Å; A140-L186 HydrophobicContact CB-CG 3.84Å; D183-L186 HydrophobicContact CB-CB 4.12Å; D183-L186 HydrophobicContact CB-CD1 4.26Å; D183-L186 HydrophobicContact CB-CG 3.98Å; D183-L186 PolarHBondContact OD1-N 2.8Å; L186-K188 PolarHBondContact O-N 2.92Å; L186-I189 HydrophobicContact CD2-CD1 3.86Å; L186-I189 WeakPolarHBondContact O-CB 3.4Å; L186-I189 PolarHBondContact O-N 2.61Å; L186-I189 VanDerWaalsContact O-N 3.17Å; L186-L193 HydrophobicContact CB-CD2 3.91Å; L186-L193 HydrophobicContact CD2-CD2 4.08Å; L186-L193 HydrophobicContact CG-CD2 4.38Å; L186-P195 HydrophobicContact CB-CB 3.98Å; L186-L197 HydrophobicContact CD1-CD2 3.52Å; L186-L197 HydrophobicContact CG-CD2 4.33Å
187S95.3Very high94.7Very high52 Ų5253 Ų5336%0.36429%0.289SS..G310 helixtrans-66.6-14.3176.1-60.80000114.3K182 D183 F185 P195K182-S187 WeakPolarHBondContact CE-OG 3.35Å; K182-S187 WeakPolarHBondContact CG-OG 3.26Å; D183-S187 WeakPolarHBondContact O-CB 3.03Å; D183-S187 PolarHBondContact O-N 3.37Å; D183-S187 PolarHBondContact O-OG 3.41Å; F185-S187 PolarHBondContact O-N 2.7Å; S187-P195 WeakPolarHBondContact OG-CB 3.42Å
188K94.1Very high94.7Very high105 Ų10553.6 Ų53.646%0.45730%0.296SS..G310 helixtrans-90.9-9.9175.9-66.4-66.9-175.8177.60113.2W160 P184 F185 L186W160-K188 HydrophobicContact CB-CB 4.07Å; W160-K188 HydrophobicContact CG-CB 4.32Å; P184-K188 WeakPolarHBondContact O-CG 3.37Å; F185-K188 WeakPolarHBondContact O-CB 3.45Å; F185-K188 PolarHBondContact O-N 3.13Å; L186-K188 PolarHBondContact O-N 2.92Å
189I91.9Very high94.6Very high33 Ų3355.3 Ų55.317%0.16931%0.306CS..  trans-74.2124.2-177.8-59.9-178.1000108.7W160 F185 L186 F191 L193W160-I189 HydrophobicContact CD2-CG1 4.25Å; W160-I189 HydrophobicContact CE3-CD1 4.35Å; W160-I189 HydrophobicContact CE3-CG1 3.73Å; W160-I189 HydrophobicContact CH2-CG2 4.38Å; W160-I189 HydrophobicContact CZ3-CG1 4.08Å; W160-I189 HydrophobicContact CZ3-CG2 4.18Å; F185-I189 HydrophobicContact CE2-CD1 4.05Å; F185-I189 HydrophobicContact CE2-CG1 4.35Å; F185-I189 HydrophobicContact CZ-CD1 4.06Å; L186-I189 HydrophobicContact CD2-CD1 3.86Å; L186-I189 WeakPolarHBondContact O-CB 3.4Å; L186-I189 PolarHBondContact O-N 2.61Å; L186-I189 VanDerWaalsContact O-N 3.17Å; I189-F191 HydrophobicContact CG2-CD2 4.01Å; I189-F191 PolarHBondContact O-N 3.43Å; I189-L193 HydrophobicContact CB-CD2 4.02Å; I189-L193 HydrophobicContact CD1-CD2 3.66Å; I189-L193 HydrophobicContact CG1-CD2 4.28Å; I189-L193 HydrophobicContact CG2-CD2 4.3Å
190P88.1Confident94.6Very high93 Ų9355 Ų5560%0.60431%0.306SS*.SBendtrans-80.93.7-170.832.9-36.7000114.3W160W160-P190 HydrophobicContact CH2-CG 4.46Å; W160-P190 HydrophobicContact CZ2-CG 3.8Å
191F85.9Confident94.6Very high134 Ų13458 Ų5859%0.58831%0.311SS*.SBendtrans-107.6156.1-179.6-50.3-74000111W160 I189 L193W160-F191 HydrophobicContact CH2-CE2 4.12Å; I189-F191 HydrophobicContact CG2-CD2 4.01Å; I189-F191 PolarHBondContact O-N 3.43Å; F191-L193 PolarHBondContact O-N 2.93Å
192P86.9Confident94.5Very high142 Ų14261.5 Ų61.592%0.92233%0.334SS*.SBendtrans-58.2110.3-179.6-2434.3000112.4
193L89.4Confident94.4Very high81 Ų8156 Ų5642%0.42431%0.309SS..  trans-149.1141.8-177.7157.771.4000108L186 I189 F191 P195L186-L193 HydrophobicContact CB-CD2 3.91Å; L186-L193 HydrophobicContact CD2-CD2 4.08Å; L186-L193 HydrophobicContact CG-CD2 4.38Å; I189-L193 HydrophobicContact CB-CD2 4.02Å; I189-L193 HydrophobicContact CD1-CD2 3.66Å; I189-L193 HydrophobicContact CG1-CD2 4.28Å; I189-L193 HydrophobicContact CG2-CD2 4.3Å; F191-L193 PolarHBondContact O-N 2.93Å; L193-P195 VanDerWaalsContact O-CD 3.28Å; L193-P195 WeakPolarHBondContact O-CD 3.5Å
194N92.4Very high94.2Very high84 Ų8460.4 Ų60.445%0.44933%0.333SS..  trans-78.3115.4166.1-175-2.6000109.2V196 Y201N194-V196 PolarHBondContact O-N 2.83Å; N194-V196 WeakPolarHBondContact OD1-CB 3.2Å; N194-V196 PolarHBondContact OD1-N 3.24Å; N194-Y201 PolarHBondContact ND2-OH 3.34Å
195P95.6Very high94Very high26 Ų2661.1 Ų61.117%0.16935%0.351CS..  trans-79-2.8-18034.3-36.9000113.2K182 D183 L186 S187 L193K182-P195 HydrophobicContact CD-CG 4.36Å; K182-P195 HydrophobicContact CG-CB 4.14Å; K182-P195 HydrophobicContact CG-CG 4.01Å; D183-P195 PolarHBondContact N-O 2.58Å; L186-P195 HydrophobicContact CB-CB 3.98Å; S187-P195 WeakPolarHBondContact OG-CB 3.42Å; L193-P195 VanDerWaalsContact O-CD 3.28Å; L193-P195 WeakPolarHBondContact O-CD 3.5Å
196V97Very high94Very high42 Ų4263 Ų6326%0.25536%0.362SS..EExtended strand (participates in β ladder)trans-86.9131.2179.6-174.40000110.5Y181 K182 N194 Y201Y181-V196 VanDerWaalsContact O-CA 3.29Å; Y181-V196 WeakPolarHBondContact O-CA 3.08Å; K182-V196 HydrophobicContact CB-CG2 4.46Å; N194-V196 PolarHBondContact O-N 2.83Å; N194-V196 WeakPolarHBondContact OD1-CB 3.2Å; N194-V196 PolarHBondContact OD1-N 3.24Å; V196-Y201 HydrophobicContact CB-CD1 4.45Å; V196-Y201 HydrophobicContact CB-CE1 3.76Å; V196-Y201 HydrophobicContact CB-CE2 4.35Å; V196-Y201 HydrophobicContact CG1-CD1 4.03Å; V196-Y201 HydrophobicContact CG1-CD2 3.95Å; V196-Y201 HydrophobicContact CG1-CE1 3.68Å; V196-Y201 HydrophobicContact CG1-CE2 3.59Å; V196-Y201 HydrophobicContact CG1-CG 4.15Å; V196-Y201 VanDerWaalsContact CG1-CZ 3.44Å; V196-Y201 WeakPolarHBondContact O-CD1 3.44Å; V196-Y201 VanDerWaalsContact O-CE1 3.28Å; V196-Y201 WeakPolarHBondContact O-CE1 3.38Å
197L96.1Very high94.1Very high27 Ų2767 Ų6714%0.14138%0.376CS..EExtended strand (participates in β ladder)trans-149.2154.2177.872.597.4000111.5L139 A140 G180 Y181 D183 L186L139-L197 HydrophobicContact CB-CD1 3.58Å; L139-L197 HydrophobicContact CD1-CD1 3.65Å; L139-L197 HydrophobicContact CG-CD1 4.1Å; A140-L197 HydrophobicContact CB-CD2 3.67Å; G180-L197 CarbonylContact C-O 3.55Å; G180-L197 VanDerWaalsContact CA-O 3.23Å; G180-L197 WeakPolarHBondContact CA-O 3.39Å; Y181-L197 WeakPolarHBondContact CD1-O 3.14Å; Y181-L197 HydrophobicContact CE1-CD1 3.8Å; Y181-L197 HydrophobicContact CE1-CG 4.3Å; Y181-L197 HydrophobicContact CE2-CG 4.47Å; Y181-L197 PolarHBondContact N-O 3.35Å; Y181-L197 PolarHBondContact O-N 2.94Å; Y181-L197 WeakPolarHBondContact OH-CD1 3.41Å; D183-L197 HydrophobicContact CB-CD2 3.62Å; D183-L197 HydrophobicContact CB-CG 4.5Å; L186-L197 HydrophobicContact CD1-CD2 3.52Å; L186-L197 HydrophobicContact CG-CD2 4.33Å
198G97.3Very high94.1Very high14 Ų1465.5 Ų65.514%0.14436%0.364CS..  trans-170.2167.6176.600000108.8I177 F200 Y201I177-G198 WeakPolarHBondContact O-CA 3.16Å; G198-F200 VanDerWaalsContact C-N 3.27Å; G198-F200 PolarHBondContact O-N 2.85Å; G198-Y201 PolarHBondContact O-N 2.77Å
199V97.9Very high94.2Very high35 Ų3560.9 Ų60.921%0.21235%0.346CS..THydrogen-bonded Turntrans-61.3-38.9-177177.80000111.4L139 I177 V388 I412 L413L139-V199 HydrophobicContact CD1-CG2 4.25Å; I177-V199 HydrophobicContact CD1-CG2 4.47Å; I177-V199 HydrophobicContact CG1-CG2 4.3Å; I177-V199 PolarHBondContact O-N 3.21Å; V199-V388 HydrophobicContact CG1-CB 4.29Å; V199-V388 HydrophobicContact CG1-CG1 4Å; V199-V388 HydrophobicContact CG1-CG2 4.19Å; V199-I412 HydrophobicContact CG2-CG2 3.93Å; V199-L413 HydrophobicContact CB-CD2 4.22Å; V199-L413 HydrophobicContact CG1-CD2 4.09Å; V199-L413 HydrophobicContact CG1-CG 4.47Å; V199-L413 HydrophobicContact CG2-CD2 3.99Å
200F97.6Very high94.4Very high38 Ų3861.7 Ų61.717%0.16735%0.351CS..THydrogen-bonded Turntrans-112.212.7178.9-58.3-80.4000112.8F65 L178 W179 G198 P202 Y203 L413 L415F65-F200 HydrophobicContact CD1-CE2 4.06Å; F65-F200 HydrophobicContact CD1-CZ 4.4Å; F65-F200 HydrophobicContact CE1-CD2 4.16Å; F65-F200 HydrophobicContact CE1-CE1 4.45Å; F65-F200 AromaticContact CE1-CE2 3.3Å; F65-F200 HydrophobicContact CE1-CE2 3.3Å; F65-F200 AromaticContact CE1-CZ 3.5Å; F65-F200 HydrophobicContact CE1-CZ 3.5Å; F65-F200 HydrophobicContact CZ-CD2 4.24Å; F65-F200 AromaticContact CZ-CE2 3.82Å; F65-F200 HydrophobicContact CZ-CE2 3.82Å; F65-F200 HydrophobicContact CZ-CZ 4.19Å; L178-F200 HydrophobicContact CD2-CD2 3.94Å; L178-F200 HydrophobicContact CD2-CE2 3.8Å; L178-F200 WeakPolarHBondContact O-CA 3.23Å; L178-F200 WeakPolarHBondContact O-CB 3.21Å; L178-F200 PolarHBondContact O-N 3.24Å; W179-F200 HydrophobicContact CE3-CB 3.98Å; W179-F200 HydrophobicContact CZ3-CB 3.74Å; W179-F200 HydrophobicContact CZ3-CD2 4.47Å; W179-F200 HydrophobicContact CZ3-CG 4.26Å; G198-F200 VanDerWaalsContact C-N 3.27Å; G198-F200 PolarHBondContact O-N 2.85Å; F200-P202 CarbonylContact O-C 3.57Å; F200-Y203 HydrophobicContact CB-CD2 4.33Å; F200-Y203 VanDerWaalsContact O-CB 3.3Å; F200-Y203 WeakPolarHBondContact O-CB 3.28Å; F200-Y203 PolarHBondContact O-N 3.48Å; F200-L413 HydrophobicContact CE2-CD1 4.19Å; F200-L413 HydrophobicContact CE2-CD2 4.22Å; F200-L413 HydrophobicContact CZ-CD1 4.22Å; F200-L415 HydrophobicContact CE1-CD2 4.11Å; F200-L415 HydrophobicContact CZ-CD2 3.68Å
201Y96.9Very high94.9Very high86 Ų8657.7 Ų57.734%0.33732%0.324SS..  trans-79.4134.7-179.1175.8-99.6000112.4W179 N194 V196 G198W179-Y201 VanDerWaalsContact O-CD2 3.24Å; W179-Y201 WeakPolarHBondContact O-CD2 3.5Å; N194-Y201 PolarHBondContact ND2-OH 3.34Å; V196-Y201 HydrophobicContact CB-CD1 4.45Å; V196-Y201 HydrophobicContact CB-CE1 3.76Å; V196-Y201 HydrophobicContact CB-CE2 4.35Å; V196-Y201 HydrophobicContact CG1-CD1 4.03Å; V196-Y201 HydrophobicContact CG1-CD2 3.95Å; V196-Y201 HydrophobicContact CG1-CE1 3.68Å; V196-Y201 HydrophobicContact CG1-CE2 3.59Å; V196-Y201 HydrophobicContact CG1-CG 4.15Å; V196-Y201 VanDerWaalsContact CG1-CZ 3.44Å; V196-Y201 WeakPolarHBondContact O-CD1 3.44Å; V196-Y201 VanDerWaalsContact O-CE1 3.28Å; V196-Y201 WeakPolarHBondContact O-CE1 3.38Å; G198-Y201 PolarHBondContact O-N 2.77Å
202P96.3Very high95.5Very high81 Ų8153.8 Ų53.853%0.52631%0.305SS..SBendcis-76.1151.2-15.532.5-34.7000111.9F200 T206F200-P202 CarbonylContact O-C 3.57Å; P202-T206 HydrophobicContact CB-CG2 3.84Å; P202-T206 HydrophobicContact CG-CG2 3.95Å
203Y96.5Very high96.1Very high24 Ų2447.1 Ų47.19%0.09426%0.262CS..  trans-124.8-74.1176.5-162.2-108.1000112.1R63 N117 A119 W179 F200 G205 T206R63-Y203 VanDerWaalsContact NH1-CZ 3.27Å; R63-Y203 PolarHBondContact NH1-OH 3.05Å; R63-Y203 PolarHBondContact NH2-OH 3.08Å; R63-Y203 VanDerWaalsContact NH2-OH 3.11Å; N117-Y203 HydrophobicContact CB-CD1 4.3Å; N117-Y203 HydrophobicContact CB-CD2 4.1Å; N117-Y203 HydrophobicContact CB-CE1 4.14Å; N117-Y203 HydrophobicContact CB-CE2 3.93Å; N117-Y203 HydrophobicContact CB-CG 4.27Å; N117-Y203 VanDerWaalsContact CB-O 3.31Å; N117-Y203 WeakPolarHBondContact CB-O 3.34Å; A119-Y203 HydrophobicContact CB-CD1 4.09Å; A119-Y203 HydrophobicContact CB-CE1 3.91Å; W179-Y203 HydrophobicContact CE3-CD1 4.35Å; W179-Y203 HydrophobicContact CE3-CG 4.26Å; W179-Y203 HydrophobicContact CH2-CD1 4.16Å; W179-Y203 AromaticContact CZ3-CD1 3.58Å; W179-Y203 HydrophobicContact CZ3-CD1 3.58Å; W179-Y203 HydrophobicContact CZ3-CD2 4.41Å; W179-Y203 HydrophobicContact CZ3-CE1 4.29Å; W179-Y203 AromaticContact CZ3-CG 3.65Å; W179-Y203 HydrophobicContact CZ3-CG 3.65Å; F200-Y203 HydrophobicContact CB-CD2 4.33Å; F200-Y203 VanDerWaalsContact O-CB 3.3Å; F200-Y203 WeakPolarHBondContact O-CB 3.28Å; F200-Y203 PolarHBondContact O-N 3.48Å; Y203-G205 PolarHBondContact O-N 3.38Å; Y203-T206 WeakPolarHBondContact O-CB 3.23Å; Y203-T206 WeakPolarHBondContact O-CG2 3.12Å; Y203-T206 PolarHBondContact O-N 2.91Å; Y203-T206 VanDerWaalsContact O-N 3.09Å; Y203-T206 PolarHBondContact O-OG1 3.29Å
204N94.7Very high96.5Very high94 Ų9445.5 Ų45.550%0.50325%0.251SS..THydrogen-bonded Turntrans-59.2131.4-177-76.71.7000111.3N117 V118 A119 T206N117-N204 WeakPolarHBondContact O-CA 3.29Å; V118-N204 WeakPolarHBondContact CA-OD1 3.41Å; A119-N204 PolarHBondContact N-OD1 2.81Å; A119-N204 PolarHBondContact O-ND2 3.31Å; N204-T206 VanDerWaalsContact C-N 3.31Å
205G91.9Very high96.7Very high69 Ų6941.6 Ų41.671%0.71123%0.231SC*.THydrogen-bonded Turntrans81.86.3-179.200000114.5N117 Y203N117-G205 PolarHBondContact O-N 3.39Å; Y203-G205 PolarHBondContact O-N 3.38Å
206T96.6Very high96.7Very high40 Ų4040.7 Ų40.725%0.24523%0.226CC..EExtended strand (participates in β ladder)trans-100.1171.3171.472.40000111.1N117 P202 Y203 N204N117-T206 WeakPolarHBondContact CB-OG1 3.45Å; N117-T206 PolarHBondContact N-O 2.72Å; N117-T206 PolarHBondContact ND2-OG1 2.8Å; P202-T206 HydrophobicContact CB-CG2 3.84Å; P202-T206 HydrophobicContact CG-CG2 3.95Å; Y203-T206 WeakPolarHBondContact O-CB 3.23Å; Y203-T206 WeakPolarHBondContact O-CG2 3.12Å; Y203-T206 PolarHBondContact O-N 2.91Å; Y203-T206 VanDerWaalsContact O-N 3.09Å; Y203-T206 PolarHBondContact O-OG1 3.29Å; N204-T206 VanDerWaalsContact C-N 3.31Å
207Y96.9Very high96.6Very high108 Ų10843.5 Ų43.542%0.42423%0.234SC..EExtended strand (participates in β ladder)trans-131.9144.4177.5-58.8-96.3000110.8E101 M114 L115 P116E101-Y207 HydrophobicContact CB-CE1 4.35Å; E101-Y207 HydrophobicContact CG-CE1 4.47Å; E101-Y207 VanDerWaalsContact OE2-CE1 3.31Å; E101-Y207 WeakPolarHBondContact OE2-CE1 3.47Å; E101-Y207 PolarHBondContact OE2-OH 2.8Å; M114-Y207 HydrophobicContact CB-CD1 4.04Å; M114-Y207 HydrophobicContact CB-CG 4.44Å; M114-Y207 VanDerWaalsContact CE-CB 3.45Å; M114-Y207 HydrophobicContact CE-CG 4.36Å; L115-Y207 CarbonylContact O-C 3.54Å; L115-Y207 VanDerWaalsContact O-CA 3.26Å; L115-Y207 WeakPolarHBondContact O-CA 3.24Å; P116-Y207 HydrophobicContact CB-CD1 3.96Å; P116-Y207 HydrophobicContact CB-CE1 3.79Å
208D96.8Very high96.4Very high19 Ų1949.4 Ų49.410%0.10226%0.261CS..EExtended strand (participates in β ladder)trans-98.4140.2165.1-173.428.6000110.7L115 Y211 Y229 S268L115-D208 HydrophobicContact CB-CB 4.4Å; L115-D208 PolarHBondContact N-O 3.49Å; L115-D208 PolarHBondContact O-N 3.49Å; D208-Y211 HydrophobicContact CB-CE2 4.34Å; D208-Y211 WeakPolarHBondContact OD2-CE2 3.33Å; D208-Y211 PolarHBondContact OD2-OH 3.11Å; D208-Y229 WeakPolarHBondContact OD1-CE2 3.29Å; D208-Y229 PolarHBondContact OD1-OH 3.4Å; D208-S268 VanDerWaalsContact OD2-CB 3.26Å; D208-S268 WeakPolarHBondContact OD2-CB 3.41Å; D208-S268 PolarHBondContact OD2-OG 3.28Å
209G94.9Very high96.2Very high8 Ų851.7 Ų51.78%0.08227%0.27CS..EExtended strand (participates in β ladder)trans122.1-169.6-171.400000112.8M114 K230M114-G209 VanDerWaalsContact SD-C 3.59Å; G209-K230 WeakPolarHBondContact O-CE 3.36Å; G209-K230 VanDerWaalsContact O-CG 3.31Å; G209-K230 WeakPolarHBondContact O-CG 3.37Å
210L97.6Very high96.1Very high51 Ų5151.3 Ų51.327%0.26727%0.267SS..EExtended strand (participates in β ladder)cis-67.8132.49.2-173.569.4000113.7M114 Y229 K230M114-L210 HydrophobicContact CG-CD1 4.23Å; M114-L210 WeakPolarHBondContact SD-CA 3.35Å; M114-L210 HydrophobicContact SD-CB 3.87Å; M114-L210 HydrophobicContact SD-CD1 3.92Å; M114-L210 PolarHBondContact SD-N 3.24Å; M114-L210 VanDerWaalsContact SD-N 3.39Å; L210-Y229 CarbonylContact O-C 3.39Å; L210-K230 PolarHBondContact O-N 3.11Å
211Y98.4Very high96Very high9 Ų952.8 Ų52.84%0.03528%0.282CS..EExtended strand (participates in β ladder)trans-96.5137.9167.3-73.4-91.7000109.6S112 Y113 D208 I226 Y229 F266 S268S112-Y211 CarbonylContact C-O 3.58Å; S112-Y211 WeakPolarHBondContact CA-O 3.28Å; Y113-Y211 HydrophobicContact CE1-CG 4.11Å; Y113-Y211 AromaticContact CE2-CD2 3.97Å; Y113-Y211 HydrophobicContact CE2-CD2 3.97Å; Y113-Y211 HydrophobicContact CE2-CG 4.16Å; Y113-Y211 AromaticContact CZ-CG 3.77Å; Y113-Y211 PolarHBondContact N-O 3.06Å; Y113-Y211 PolarHBondContact O-N 3.33Å; D208-Y211 HydrophobicContact CB-CE2 4.34Å; D208-Y211 WeakPolarHBondContact OD2-CE2 3.33Å; D208-Y211 PolarHBondContact OD2-OH 3.11Å; Y211-I226 HydrophobicContact CD1-CD1 4.17Å; Y211-I226 HydrophobicContact CD1-CG1 4.34Å; Y211-I226 HydrophobicContact CE1-CD1 4.12Å; Y211-Y229 AromaticContact CD1-CD2 3.93Å; Y211-Y229 HydrophobicContact CD1-CD2 3.93Å; Y211-Y229 HydrophobicContact CD2-CD2 4.31Å; Y211-Y229 HydrophobicContact CD2-CE2 4.41Å; Y211-Y229 AromaticContact CE1-CD2 3.58Å; Y211-Y229 HydrophobicContact CE1-CD2 3.58Å; Y211-Y229 HydrophobicContact CE1-CE2 4.02Å; Y211-Y229 AromaticContact CE2-CD2 3.98Å; Y211-Y229 HydrophobicContact CE2-CD2 3.98Å; Y211-Y229 AromaticContact CE2-CE2 3.75Å; Y211-Y229 HydrophobicContact CE2-CE2 3.75Å; Y211-Y229 HydrophobicContact CG-CD2 4.28Å; Y211-Y229 AromaticContact CZ-CD2 3.6Å; Y211-Y229 AromaticContact CZ-CE2 3.52Å; Y211-F266 HydrophobicContact CE1-CD1 4.06Å; Y211-F266 HydrophobicContact CE1-CE1 4.13Å; Y211-S268 PolarHBondContact OH-OG 3.46Å
212R98.3Very high96Very high51 Ų5153.2 Ų53.219%0.19229%0.285CS..EExtended strand (participates in β ladder)trans-122.7118.6166.2-178.7-175.2-178.693.3-4.4107.9N106 D108 T110 D227 T228N106-R212 PolarHBondContact ND2-NH1 2.84Å; N106-R212 PolarHBondContact OD1-NH1 3.24Å; D108-R212 IonicContact OD1-CZ 2.8Å; D108-R212 IonicContact OD1-NH2 2.88Å; D108-R212 PolarHBondContact OD1-NH2 3.5Å; D108-R212 IonicContact OD2-CZ 3.62Å; D108-R212 IonicContact OD2-NE 3.64Å; D108-R212 IonicContact OD2-NH2 2.66Å; D108-R212 PolarHBondContact OD2-NH2 2.87Å; T110-R212 HydrophobicContact CG2-CG 4.38Å; T110-R212 PolarHBondContact OG1-NE 2.98Å; T110-R212 VanDerWaalsContact OG1-NE 3.13Å; T110-R212 PolarHBondContact OG1-NH2 3.26Å; T110-R212 VanDerWaalsContact OG1-NH2 3.08Å; R212-D227 VanDerWaalsContact CD-OD2 3.31Å; R212-D227 WeakPolarHBondContact CD-OD2 3.2Å; R212-D227 HydrophobicContact CG-CB 4.31Å; R212-D227 IonicContact NE-OD2 3.6Å; R212-D227 PolarHBondContact NE-OD2 2.84Å; R212-D227 PolarHBondContact O-N 3.02Å; R212-T228 WeakPolarHBondContact CB-OG1 3.39Å; R212-T228 PolarHBondContact N-O 2.68Å; R212-T228 PolarHBondContact O-N 3.39Å
213V98.3Very high96Very high3 Ų349.6 Ų49.62%0.01826%0.262CS..EExtended strand (participates in β ladder)trans-123.6149.9-176.3-56.80000110.9I44 T110 I111 Y113 I225 I226I44-V213 HydrophobicContact CD1-CG2 4.4Å; T110-V213 CarbonylContact C-O 3.34Å; T110-V213 WeakPolarHBondContact CA-O 3.35Å; T110-V213 WeakPolarHBondContact CB-O 3.43Å; I111-V213 HydrophobicContact CG2-CG2 3.51Å; I111-V213 PolarHBondContact N-O 2.95Å; I111-V213 PolarHBondContact O-N 3.49Å; Y113-V213 HydrophobicContact CE1-CG1 3.98Å; Y113-V213 HydrophobicContact CE1-CG2 4.28Å; V213-I225 CarbonylContact C-O 3.35Å; V213-I225 VanDerWaalsContact CA-O 3.25Å; V213-I225 WeakPolarHBondContact CA-O 3.32Å; V213-I226 HydrophobicContact CG1-CB 4.45Å; V213-I226 HydrophobicContact CG1-CG1 3.87Å
214F98.3Very high96.1Very high47 Ų4748.6 Ų48.621%0.20626%0.258CS..EExtended strand (participates in β ladder)trans-70.7134.9172.9-65.1-78.4000110.6T110 K222 A224 I225 D227T110-F214 HydrophobicContact CG2-CD1 3.64Å; T110-F214 HydrophobicContact CG2-CE1 3.82Å; T110-F214 HydrophobicContact CG2-CG 4.32Å; F214-K222 HydrophobicContact CB-CB 3.93Å; F214-K222 WeakPolarHBondContact CB-O 3.35Å; F214-K222 HydrophobicContact CD2-CB 4.24Å; F214-K222 HydrophobicContact CG-CB 4.06Å; F214-A224 PolarHBondContact O-N 3.31Å; F214-I225 HydrophobicContact CD2-CB 4.22Å; F214-I225 HydrophobicContact CD2-CG2 4.44Å; F214-I225 WeakPolarHBondContact CD2-O 3.32Å; F214-I225 PolarHBondContact N-O 3.28Å; F214-D227 HydrophobicContact CD2-CB 4.26Å; F214-D227 HydrophobicContact CE2-CB 3.66Å; F214-D227 HydrophobicContact CZ-CB 3.8Å
215T97.1Very high96.2Very high2 Ų246.4 Ų46.41%0.01225%0.246CC..  trans-76.8-24.1-179.359.90000113.3V43 I44 G109 I111 K217V43-T215 WeakPolarHBondContact CA-O 3.28Å; I44-T215 PolarHBondContact N-O 2.77Å; I44-T215 WeakPolarHBondContact O-CB 3.29Å; I44-T215 WeakPolarHBondContact O-CG2 3.27Å; G109-T215 WeakPolarHBondContact O-CB 3.42Å; G109-T215 WeakPolarHBondContact O-CG2 3.14Å; G109-T215 PolarHBondContact O-N 3.39Å; G109-T215 PolarHBondContact O-OG1 2.67Å; I111-T215 HydrophobicContact CB-CG2 3.79Å; I111-T215 HydrophobicContact CG2-CG2 3.81Å; T215-K217 WeakPolarHBondContact OG1-CG 3.31Å; T215-K217 PolarHBondContact OG1-N 3.44Å
216G96.1Very high96.6Very high6 Ų643.4 Ų43.46%0.06221%0.214CC..SBendtrans87.6-1.3-170.800000115.3E218 D219 I220 T223G216-E218 VanDerWaalsContact C-N 3.33Å; G216-E218 PolarHBondContact O-N 2.94Å; G216-D219 WeakPolarHBondContact CA-O 3.23Å; G216-D219 CarbonylContact O-C 3.57Å; G216-I220 PolarHBondContact O-N 3.05Å; G216-T223 WeakPolarHBondContact CA-OG1 3.33Å
217K93.2Very high96.6Very high101 Ų10142.3 Ų42.344%0.43921%0.206SC..SBendtrans-58.2-43.3179.5-76.7178.7-178174.30112.3V43 S45 E105 T215V43-K217 HydrophobicContact CG1-CB 4.34Å; V43-K217 HydrophobicContact CG1-CG 3.44Å; V43-K217 VanDerWaalsContact CG1-CG 3.44Å; S45-K217 VanDerWaalsContact OG-CE 3.28Å; S45-K217 WeakPolarHBondContact OG-CE 3.38Å; S45-K217 PolarHBondContact OG-NZ 3.49Å; E105-K217 IonicContact OE2-NZ 3.89Å; E105-K217 PolarHBondContact OE2-NZ 2.93Å; T215-K217 WeakPolarHBondContact OG1-CG 3.31Å; T215-K217 PolarHBondContact OG1-N 3.44Å
218E92.2Very high96.7Very high152 Ų15238 Ų3871%0.7119%0.191SC*.SBendtrans-86.5-43.7-179.9-61.9-178.3178.400112.3G216G216-E218 VanDerWaalsContact C-N 3.33Å; G216-E218 PolarHBondContact O-N 2.94Å
219D94.8Very high96.8Very high62 Ų6237.9 Ų37.933%0.33219%0.19SC..  trans-142.7106.4-177.9-179.80.2000109.7G216 S221 K222G216-D219 WeakPolarHBondContact CA-O 3.23Å; G216-D219 CarbonylContact O-C 3.57Å; D219-S221 PolarHBondContact O-N 2.03Å; D219-S221 VanDerWaalsContact OD1-CB 3.28Å; D219-S221 WeakPolarHBondContact OD1-CB 3.49Å; D219-S221 PolarHBondContact OD1-N 3.11Å; D219-S221 PolarHBondContact OD1-OG 2.58Å; D219-S221 PolarHBondContact OD2-OG 2.79Å; D219-S221 VanDerWaalsContact OD2-OG 3.04Å; D219-K222 HydrophobicContact CB-CD 4.32Å; D219-K222 HydrophobicContact CB-CG 4.39Å; D219-K222 PolarHBondContact O-N 3.24Å; D219-K222 WeakPolarHBondContact OD2-CE 3.33Å
220I95.1Very high96.9Very high27 Ų2742.6 Ų42.614%0.13821%0.208CC..G310 helixtrans-64.3-21.1-178.5-161.970.1000112.9K39 T42 V43 G216 K222 T223 P255K39-I220 HydrophobicContact CB-CG1 4.41Å; K39-I220 HydrophobicContact CD-CG2 4.15Å; K39-I220 HydrophobicContact CG-CB 4.44Å; K39-I220 HydrophobicContact CG-CG1 4.24Å; K39-I220 HydrophobicContact CG-CG2 3.97Å; K39-I220 WeakPolarHBondContact O-CD1 3.25Å; T42-I220 WeakPolarHBondContact OG1-CD1 3.03Å; V43-I220 HydrophobicContact CG2-CD1 3.76Å; G216-I220 PolarHBondContact O-N 3.05Å; I220-K222 PolarHBondContact O-N 3.05Å; I220-T223 WeakPolarHBondContact CD1-OG1 3.46Å; I220-T223 PolarHBondContact O-N 3.38Å; I220-T223 PolarHBondContact O-OG1 3.12Å; I220-P255 HydrophobicContact CD1-CG 4.46Å; I220-P255 HydrophobicContact CG1-CG 3.55Å
221S95.7Very high96.9Very high68 Ų6846 Ų4648%0.47623%0.226SC..G310 helixtrans-69-12.2175.476.10000112.7D219 P254D219-S221 PolarHBondContact O-N 2.03Å; D219-S221 VanDerWaalsContact OD1-CB 3.28Å; D219-S221 WeakPolarHBondContact OD1-CB 3.49Å; D219-S221 PolarHBondContact OD1-N 3.11Å; D219-S221 PolarHBondContact OD1-OG 2.58Å; D219-S221 PolarHBondContact OD2-OG 2.79Å; D219-S221 VanDerWaalsContact OD2-OG 3.04Å; S221-P254 WeakPolarHBondContact O-CB 3.43Å; S221-P254 WeakPolarHBondContact O-CG 3.41Å
222K96.9Very high96.8Very high95 Ų9550.9 Ų50.941%0.41325%0.248SC..G310 helixtrans-103.3-6177.9-63.2-178.1-176.71740114.2F214 D219 I220 A224 I225F214-K222 HydrophobicContact CB-CB 3.93Å; F214-K222 WeakPolarHBondContact CB-O 3.35Å; F214-K222 HydrophobicContact CD2-CB 4.24Å; F214-K222 HydrophobicContact CG-CB 4.06Å; D219-K222 HydrophobicContact CB-CD 4.32Å; D219-K222 HydrophobicContact CB-CG 4.39Å; D219-K222 PolarHBondContact O-N 3.24Å; D219-K222 WeakPolarHBondContact OD2-CE 3.33Å; I220-K222 PolarHBondContact O-N 3.05Å; K222-A224 PolarHBondContact O-N 3.41Å; K222-I225 VanDerWaalsContact O-CB 3.24Å; K222-I225 WeakPolarHBondContact O-CB 3.05Å; K222-I225 WeakPolarHBondContact O-CG1 3.3Å; K222-I225 PolarHBondContact O-N 2.82Å
223T96.8Very high96.7Very high6 Ų655.9 Ų55.94%0.03727%0.267CS..THydrogen-bonded Turntrans-47.6132.6-177.3-55.40000112T42 I44 G216 I220 I225T42-T223 VanDerWaalsContact O-CG2 3.31Å; T42-T223 WeakPolarHBondContact O-CG2 3.35Å; I44-T223 HydrophobicContact CD1-CG2 4.27Å; I44-T223 HydrophobicContact CG1-CG2 4.1Å; G216-T223 WeakPolarHBondContact CA-OG1 3.33Å; I220-T223 WeakPolarHBondContact CD1-OG1 3.46Å; I220-T223 PolarHBondContact O-N 3.38Å; I220-T223 PolarHBondContact O-OG1 3.12Å; T223-I225 PolarHBondContact O-N 2.94Å
224A97.3Very high96.7Very high2 Ų259 Ų592%0.01728%0.283CS..THydrogen-bonded Turntrans64.3-4.2-17900000116.2I44 F214 K222 I226 T248 S252I44-A224 HydrophobicContact CD1-CB 4.01Å; F214-A224 PolarHBondContact O-N 3.31Å; K222-A224 PolarHBondContact O-N 3.41Å; A224-I226 PolarHBondContact O-N 3.14Å; A224-T248 HydrophobicContact CB-CG2 4.04Å; A224-T248 WeakPolarHBondContact O-CA 3.32Å; A224-T248 WeakPolarHBondContact O-CB 3.42Å; A224-S252 WeakPolarHBondContact CB-OG 3.32Å
225I98.3Very high96.5Very high48 Ų4857.3 Ų57.325%0.24628%0.276CS..  trans-64.4133.8173.7-61-176.4000108.7V213 F214 K222 T223 D227 G247 T248 P254V213-I225 CarbonylContact C-O 3.35Å; V213-I225 VanDerWaalsContact CA-O 3.25Å; V213-I225 WeakPolarHBondContact CA-O 3.32Å; F214-I225 HydrophobicContact CD2-CB 4.22Å; F214-I225 HydrophobicContact CD2-CG2 4.44Å; F214-I225 WeakPolarHBondContact CD2-O 3.32Å; F214-I225 PolarHBondContact N-O 3.28Å; K222-I225 VanDerWaalsContact O-CB 3.24Å; K222-I225 WeakPolarHBondContact O-CB 3.05Å; K222-I225 WeakPolarHBondContact O-CG1 3.3Å; K222-I225 PolarHBondContact O-N 2.82Å; T223-I225 PolarHBondContact O-N 2.94Å; I225-D227 PolarHBondContact O-N 3.16Å; I225-G247 WeakPolarHBondContact CA-O 2.96Å; I225-T248 HydrophobicContact CG1-CG2 4.07Å; I225-P254 HydrophobicContact CD1-CG 4.19Å; I225-P254 HydrophobicContact CG1-CG 4.27Å
226I98.6Very high96.5Very high7 Ų760.8 Ų60.84%0.03630%0.301CS..EExtended strand (participates in β ladder)trans-74.4118.8178.6-60.4161000108.4Y211 V213 A224 T228 V245 G247 F266Y211-I226 HydrophobicContact CD1-CD1 4.17Å; Y211-I226 HydrophobicContact CD1-CG1 4.34Å; Y211-I226 HydrophobicContact CE1-CD1 4.12Å; V213-I226 HydrophobicContact CG1-CB 4.45Å; V213-I226 HydrophobicContact CG1-CG1 3.87Å; A224-I226 PolarHBondContact O-N 3.14Å; I226-T228 WeakPolarHBondContact CG2-O 3.16Å; I226-V245 HydrophobicContact CB-CG1 4.07Å; I226-V245 HydrophobicContact CD1-CG1 4.36Å; I226-V245 HydrophobicContact CG2-CG1 3.62Å; I226-G247 PolarHBondContact N-O 2.83Å; I226-F266 HydrophobicContact CD1-CB 3.76Å; I226-F266 HydrophobicContact CD1-CD1 3.97Å; I226-F266 HydrophobicContact CD1-CG 4.34Å
227D97.9Very high96.4Very high16 Ų1664.2 Ų64.29%0.08631%0.312CS..EExtended strand (participates in β ladder)trans-78.5-49.7169.6176.641.5000109.9R212 F214 I225 R233R212-D227 VanDerWaalsContact CD-OD2 3.31Å; R212-D227 WeakPolarHBondContact CD-OD2 3.2Å; R212-D227 HydrophobicContact CG-CB 4.31Å; R212-D227 IonicContact NE-OD2 3.6Å; R212-D227 PolarHBondContact NE-OD2 2.84Å; R212-D227 PolarHBondContact O-N 3.02Å; F214-D227 HydrophobicContact CD2-CB 4.26Å; F214-D227 HydrophobicContact CE2-CB 3.66Å; F214-D227 HydrophobicContact CZ-CB 3.8Å; I225-D227 PolarHBondContact O-N 3.16Å; D227-R233 WeakPolarHBondContact O-CG 3.22Å; D227-R233 IonicContact OD1-CZ 3.26Å; D227-R233 VanDerWaalsContact OD1-CZ 3.26Å; D227-R233 IonicContact OD1-NE 3.65Å; D227-R233 PolarHBondContact OD1-NE 2.84Å; D227-R233 VanDerWaalsContact OD1-NE 3.07Å; D227-R233 IonicContact OD1-NH2 2.7Å; D227-R233 PolarHBondContact OD1-NH2 2.88Å
228T98.3Very high96.6Very high17 Ų1760.2 Ų60.210%0.10429%0.294CS..EExtended strand (participates in β ladder)trans-142.5148.1175.461.90000112.3R212 I226 K232 R233R212-T228 WeakPolarHBondContact CB-OG1 3.39Å; R212-T228 PolarHBondContact N-O 2.68Å; R212-T228 PolarHBondContact O-N 3.39Å; I226-T228 WeakPolarHBondContact CG2-O 3.16Å; T228-K232 CarbonylContact C-O 3.49Å; T228-K232 VanDerWaalsContact CA-O 3.31Å; T228-K232 WeakPolarHBondContact CA-O 3.39Å; T228-K232 WeakPolarHBondContact CB-O 3.03Å; T228-R233 HydrophobicContact CG2-CG 3.91Å
229Y98.3Very high96.7Very high18 Ų1859.9 Ų59.97%0.07129%0.293CS..EExtended strand (participates in β ladder)trans-117.4126.1166.5174.4-107.3000108.2D208 L210 Y211 N231 K232 L235 F266D208-Y229 WeakPolarHBondContact OD1-CE2 3.29Å; D208-Y229 PolarHBondContact OD1-OH 3.4Å; L210-Y229 CarbonylContact O-C 3.39Å; Y211-Y229 AromaticContact CD1-CD2 3.93Å; Y211-Y229 HydrophobicContact CD1-CD2 3.93Å; Y211-Y229 HydrophobicContact CD2-CD2 4.31Å; Y211-Y229 HydrophobicContact CD2-CE2 4.41Å; Y211-Y229 AromaticContact CE1-CD2 3.58Å; Y211-Y229 HydrophobicContact CE1-CD2 3.58Å; Y211-Y229 HydrophobicContact CE1-CE2 4.02Å; Y211-Y229 AromaticContact CE2-CD2 3.98Å; Y211-Y229 HydrophobicContact CE2-CD2 3.98Å; Y211-Y229 AromaticContact CE2-CE2 3.75Å; Y211-Y229 HydrophobicContact CE2-CE2 3.75Å; Y211-Y229 HydrophobicContact CG-CD2 4.28Å; Y211-Y229 AromaticContact CZ-CD2 3.6Å; Y211-Y229 AromaticContact CZ-CE2 3.52Å; Y229-N231 PolarHBondContact O-N 3.45Å; Y229-K232 PolarHBondContact N-O 2.82Å; Y229-K232 PolarHBondContact O-N 2.96Å; Y229-K232 VanDerWaalsContact O-O 3.07Å; Y229-L235 HydrophobicContact CD1-CD2 3.92Å; Y229-L235 HydrophobicContact CE1-CD2 4.42Å; Y229-F266 AromaticContact CD1-CE1 3.94Å; Y229-F266 HydrophobicContact CD1-CE1 3.94Å; Y229-F266 AromaticContact CD1-CZ 3.89Å; Y229-F266 HydrophobicContact CD1-CZ 3.89Å; Y229-F266 AromaticContact CD2-CE1 3.83Å; Y229-F266 HydrophobicContact CD2-CE1 3.83Å; Y229-F266 HydrophobicContact CE1-CE1 4.19Å; Y229-F266 AromaticContact CE1-CZ 4Å; Y229-F266 HydrophobicContact CE1-CZ 4Å; Y229-F266 HydrophobicContact CE2-CE1 4.08Å; Y229-F266 AromaticContact CG-CE1 3.75Å; Y229-F266 HydrophobicContact CG-CE1 3.75Å; Y229-F266 HydrophobicContact CG-CZ 4.18Å
230K97.1Very high96.7Very high106 Ų10659.3 Ų59.346%0.46130%0.302SS..THydrogen-bonded Turntrans50.844.1-173.5-66.2177.5174167.90112.4G209 L210 K232G209-K230 WeakPolarHBondContact O-CE 3.36Å; G209-K230 VanDerWaalsContact O-CG 3.31Å; G209-K230 WeakPolarHBondContact O-CG 3.37Å; L210-K230 PolarHBondContact O-N 3.11Å; K230-K232 PolarHBondContact O-N 2.82Å
231N97.1Very high96.7Very high124 Ų12461.9 Ų61.966%0.66331%0.313SS*.THydrogen-bonded Turntrans61.417.7-178.8-54.6-43000115Y229Y229-N231 PolarHBondContact O-N 3.45Å
232K97Very high96.8Very high111 Ų11158.9 Ų58.948%0.48329%0.292SS..BIsolated β-bridgetrans-126148.6176.1-63.8-178.3173.2-176.50111.1T228 Y229 K230 N234 S236T228-K232 CarbonylContact C-O 3.49Å; T228-K232 VanDerWaalsContact CA-O 3.31Å; T228-K232 WeakPolarHBondContact CA-O 3.39Å; T228-K232 WeakPolarHBondContact CB-O 3.03Å; Y229-K232 PolarHBondContact N-O 2.82Å; Y229-K232 PolarHBondContact O-N 2.96Å; Y229-K232 VanDerWaalsContact O-O 3.07Å; K230-K232 PolarHBondContact O-N 2.82Å; K232-N234 VanDerWaalsContact C-N 3.35Å; K232-N234 WeakPolarHBondContact CB-O 3.17Å; K232-S236 PolarHBondContact NZ-OG 3.19Å
233R96.8Very high96.8Very high156 Ų15655 Ų5559%0.58928%0.275SS*.SBendtrans-84.5-15.3169.2-62.2-157.3167.31550.4113D227 T228 V245D227-R233 WeakPolarHBondContact O-CG 3.22Å; D227-R233 IonicContact OD1-CZ 3.26Å; D227-R233 VanDerWaalsContact OD1-CZ 3.26Å; D227-R233 IonicContact OD1-NE 3.65Å; D227-R233 PolarHBondContact OD1-NE 2.84Å; D227-R233 VanDerWaalsContact OD1-NE 3.07Å; D227-R233 IonicContact OD1-NH2 2.7Å; D227-R233 PolarHBondContact OD1-NH2 2.88Å; T228-R233 HydrophobicContact CG2-CG 3.91Å; R233-V245 WeakPolarHBondContact O-CB 3.29Å; R233-V245 PolarHBondContact O-N 3.11Å
234N97.2Very high96.8Very high67 Ų6757.6 Ų57.636%0.35829%0.289SS..BIsolated β-bridgetrans-125.3147.4-178.5-65.433.5000109.7K232 D243 L244K232-N234 VanDerWaalsContact C-N 3.35Å; K232-N234 WeakPolarHBondContact CB-O 3.17Å; N234-D243 CarbonylContact C-O 3.48Å; N234-D243 WeakPolarHBondContact CA-O 3.48Å; N234-D243 HydrophobicContact CB-CB 4.49Å; N234-D243 WeakPolarHBondContact CB-OD2 3.47Å; N234-L244 WeakPolarHBondContact OD1-CD2 2.99Å
235L95.6Very high96.9Very high13 Ų1358.1 Ų58.17%0.06829%0.292CS..  trans-79.9-21.4-171.7-63.2168.7000113.6Y229 Y237 D243 V245 F266 C271Y229-L235 HydrophobicContact CD1-CD2 3.92Å; Y229-L235 HydrophobicContact CE1-CD2 4.42Å; L235-Y237 HydrophobicContact CB-CD2 3.57Å; L235-Y237 HydrophobicContact CB-CE2 4.04Å; L235-Y237 HydrophobicContact CB-CG 4.14Å; L235-Y237 HydrophobicContact CD1-CD2 4.41Å; L235-Y237 HydrophobicContact CG-CD2 4.43Å; L235-D243 WeakPolarHBondContact CB-OD1 3.08Å; L235-D243 PolarHBondContact N-O 2.85Å; L235-D243 PolarHBondContact N-OD1 3.35Å; L235-D243 PolarHBondContact N-OD2 3.18Å; L235-V245 HydrophobicContact CD2-CG2 3.6Å; L235-V245 HydrophobicContact CG-CG2 3.8Å; L235-F266 HydrophobicContact CD1-CD2 4.46Å; L235-F266 HydrophobicContact CD1-CE2 3.81Å; L235-F266 HydrophobicContact CD2-CE2 3.59Å; L235-F266 HydrophobicContact CD2-CZ 3.69Å; L235-F266 HydrophobicContact CG-CE2 4.3Å; L235-C271 VanDerWaalsContact CD1-O 3.29Å; L235-C271 WeakPolarHBondContact CD1-O 3.5Å
236S95.6Very high96.8Very high75 Ų7558.7 Ų58.752%0.52430%0.295SS..SBendtrans62.229.8-170.2-41.40000113K232 D243K232-S236 PolarHBondContact NZ-OG 3.19Å; S236-D243 WeakPolarHBondContact CA-OD2 3.48Å; S236-D243 VanDerWaalsContact N-CG 3.28Å; S236-D243 PolarHBondContact N-OD1 3Å; S236-D243 PolarHBondContact N-OD2 2Å
237Y95.3Very high96.7Very high77 Ų7759 Ų5930%0.30230%0.3SS..SBendtrans-115.1-30.4178.2-59.2-37000113.1L235 D243 C271 A331 C332L235-Y237 HydrophobicContact CB-CD2 3.57Å; L235-Y237 HydrophobicContact CB-CE2 4.04Å; L235-Y237 HydrophobicContact CB-CG 4.14Å; L235-Y237 HydrophobicContact CD1-CD2 4.41Å; L235-Y237 HydrophobicContact CG-CD2 4.43Å; Y237-D243 PolarHBondContact N-OD1 3.28Å; Y237-C271 HydrophobicContact CD2-CB 4.06Å; Y237-C271 HydrophobicContact CE2-CB 4.24Å; Y237-A331 HydrophobicContact CD1-CB 4.17Å; Y237-A331 HydrophobicContact CG-CB 4.38Å; Y237-C332 HydrophobicContact CD1-CB 4.21Å; Y237-C332 HydrophobicContact CD2-CB 3.79Å; Y237-C332 HydrophobicContact CE1-CB 3.88Å; Y237-C332 HydrophobicContact CE2-CB 3.45Å; Y237-C332 VanDerWaalsContact CE2-CB 3.45Å; Y237-C332 HydrophobicContact CG-CB 4.18Å
238W96.7Very high96.7Very high18 Ų1858.2 Ų58.27%0.06830%0.296CS..SBendtrans-121.1165.4-174-47.6103.4000111.2C242 D243 C271 F311 T313 L327 D328W238-C242 HydrophobicContact CB-CB 3.63Å; W238-C242 HydrophobicContact CG-CB 4.18Å; W238-D243 HydrophobicContact CB-CB 4.06Å; W238-D243 PolarHBondContact N-OD1 2.77Å; W238-D243 VanDerWaalsContact O-CB 3.3Å; W238-D243 WeakPolarHBondContact O-CB 3.3Å; W238-D243 VanDerWaalsContact O-CG 3.27Å; W238-C271 PolarHBondContact NE1-O 2.88Å; W238-F311 AromaticContact CD2-CD1 3.56Å; W238-F311 HydrophobicContact CD2-CD1 3.56Å; W238-F311 AromaticContact CD2-CE1 3.81Å; W238-F311 HydrophobicContact CD2-CE1 3.81Å; W238-F311 AromaticContact CE2-CD1 3.76Å; W238-F311 AromaticContact CE2-CE1 3.83Å; W238-F311 AromaticContact CE3-CD1 3.61Å; W238-F311 HydrophobicContact CE3-CD1 3.61Å; W238-F311 HydrophobicContact CE3-CE1 4.33Å; W238-F311 HydrophobicContact CG-CD1 4.11Å; W238-F311 AromaticContact CG-CE1 3.93Å; W238-F311 HydrophobicContact CG-CE1 3.93Å; W238-F311 AromaticContact CH2-CD1 3.98Å; W238-F311 HydrophobicContact CH2-CD1 3.98Å; W238-F311 AromaticContact CZ2-CD1 3.98Å; W238-F311 HydrophobicContact CZ2-CD1 3.98Å; W238-F311 HydrophobicContact CZ2-CE1 4.34Å; W238-F311 HydrophobicContact CZ3-CB 4.3Å; W238-F311 AromaticContact CZ3-CD1 3.82Å; W238-F311 HydrophobicContact CZ3-CD1 3.82Å; W238-F311 AromaticContact NE1-CE1 3.99Å; W238-T313 HydrophobicContact CE3-CG2 4.41Å; W238-T313 HydrophobicContact CZ3-CG2 3.84Å; W238-L327 HydrophobicContact CH2-CD1 3.57Å; W238-L327 HydrophobicContact CH2-CD2 4.47Å; W238-L327 HydrophobicContact CH2-CG 3.99Å; W238-L327 HydrophobicContact CZ2-CD1 4.15Å; W238-L327 HydrophobicContact CZ2-CD2 4.39Å; W238-L327 HydrophobicContact CZ2-CG 4.39Å; W238-L327 HydrophobicContact CZ3-CD1 4.25Å; W238-D328 WeakPolarHBondContact CH2-O 3.36Å
239E94.3Very high96.6Very high145 Ų14559.6 Ų59.668%0.67830%0.303SS*.SBendtrans-89.8158.6172.5-63.4-173.7171.400111.5C242 C310E239-C242 WeakPolarHBondContact O-CB 3.49Å; E239-C242 PolarHBondContact O-N 2.81Å; E239-C310 HydrophobicContact CB-CB 4.14Å; E239-C310 WeakPolarHBondContact O-CB 3.43Å; E239-C310 PolarHBondContact O-SG 3.43Å; E239-C310 VanDerWaalsContact O-SG 3.4Å
240G94.5Very high96.5Very high50 Ų5059.1 Ų59.152%0.51530%0.303SS..G310 helixtrans56.7-137.817100000114.5C242G240-C242 VanDerWaalsContact C-N 3.29Å; G240-C242 PolarHBondContact O-N 2.99Å
241H95.4Very high96.3Very high81 Ų8156.8 Ų56.838%0.37530%0.304SS..G310 helixtrans-75.3-16.4-177.263.4-86000113.7D243 L244 D307 Y309 C310H241-D243 PolarHBondContact O-N 3.2Å; H241-L244 HydrophobicContact CB-CD1 4.22Å; H241-L244 WeakPolarHBondContact O-CB 3.46Å; H241-L244 WeakPolarHBondContact O-CG 3.42Å; H241-L244 PolarHBondContact O-N 3.15Å; H241-D307 PolarHBondContact CE1-O 2.87Å; H241-D307 VanDerWaalsContact CE1-O 3.32Å; H241-D307 PolarHBondContact NE2-O 3.12Å; H241-Y309 AromaticContact CE1-CE1 3.65Å; H241-C310 VanDerWaalsContact CE1-SG 3.52Å
242C96.9Very high96.2Very high5 Ų551.7 Ų51.73%0.03428%0.278CS..G310 helixtrans-63.6-23.8178.1-70.10000112.5W238 E239 G240 L244 C310 F311W238-C242 HydrophobicContact CB-CB 3.63Å; W238-C242 HydrophobicContact CG-CB 4.18Å; E239-C242 WeakPolarHBondContact O-CB 3.49Å; E239-C242 PolarHBondContact O-N 2.81Å; G240-C242 VanDerWaalsContact C-N 3.29Å; G240-C242 PolarHBondContact O-N 2.99Å; C242-L244 VanDerWaalsContact C-N 3.33Å; C242-C310 HydrophobicContact CB-CB 3.66Å; C242-C310 WeakPolarHBondContact CB-SG 3.31Å; C242-C310 VanDerWaalsContact SG-C 3.54Å; C242-C310 VanDerWaalsContact SG-CA 3.6Å; C242-C310 WeakPolarHBondContact SG-CB 3.46Å; C242-C310 CovalentContact SG-SG 2.02Å; C242-C310 PolarHBondContact SG-SG 2.82Å; C242-F311 HydrophobicContact CB-CD1 3.98Å; C242-F311 HydrophobicContact CB-CD2 4.26Å; C242-F311 HydrophobicContact CB-CE1 3.49Å; C242-F311 VanDerWaalsContact CB-CE1 3.49Å; C242-F311 HydrophobicContact CB-CE2 3.78Å; C242-F311 HydrophobicContact CB-CG 4.33Å; C242-F311 HydrophobicContact CB-CZ 3.37Å; C242-F311 WeakPolarHBondContact SG-CD2 3.5Å; C242-F311 WeakPolarHBondContact SG-CE2 3.45Å; C242-F311 VanDerWaalsContact SG-CZ 3.52Å
243D97.4Very high96.3Very high13 Ų1346.7 Ų46.77%0.0726%0.256CS..G310 helixtrans-83.3-9-176.2-152.441.4000113.8N234 L235 S236 Y237 W238 H241N234-D243 CarbonylContact C-O 3.48Å; N234-D243 WeakPolarHBondContact CA-O 3.48Å; N234-D243 HydrophobicContact CB-CB 4.49Å; N234-D243 WeakPolarHBondContact CB-OD2 3.47Å; L235-D243 WeakPolarHBondContact CB-OD1 3.08Å; L235-D243 PolarHBondContact N-O 2.85Å; L235-D243 PolarHBondContact N-OD1 3.35Å; L235-D243 PolarHBondContact N-OD2 3.18Å; S236-D243 WeakPolarHBondContact CA-OD2 3.48Å; S236-D243 VanDerWaalsContact N-CG 3.28Å; S236-D243 PolarHBondContact N-OD1 3Å; S236-D243 PolarHBondContact N-OD2 2Å; Y237-D243 PolarHBondContact N-OD1 3.28Å; W238-D243 HydrophobicContact CB-CB 4.06Å; W238-D243 PolarHBondContact N-OD1 2.77Å; W238-D243 VanDerWaalsContact O-CB 3.3Å; W238-D243 WeakPolarHBondContact O-CB 3.3Å; W238-D243 VanDerWaalsContact O-CG 3.27Å; H241-D243 PolarHBondContact O-N 3.2Å
244L97.7Very high96.3Very high61 Ų6140.1 Ų40.132%0.31923%0.234SC..BIsolated β-bridgetrans-72.3134.1-175.4-63.8174.7000112N234 H241 C242 N246 S273N234-L244 WeakPolarHBondContact OD1-CD2 2.99Å; H241-L244 HydrophobicContact CB-CD1 4.22Å; H241-L244 WeakPolarHBondContact O-CB 3.46Å; H241-L244 WeakPolarHBondContact O-CG 3.42Å; H241-L244 PolarHBondContact O-N 3.15Å; C242-L244 VanDerWaalsContact C-N 3.33Å; L244-N246 WeakPolarHBondContact CB-ND2 3.42Å; L244-N246 PolarHBondContact O-N 3.44Å; L244-S273 PolarHBondContact O-OG 3.22Å
245V97.8Very high96.2Very high12 Ų1237.7 Ų37.77%0.07322%0.221CC..  trans-82.794167.6-176.60000108.4I226 R233 L235 F266I226-V245 HydrophobicContact CB-CG1 4.07Å; I226-V245 HydrophobicContact CD1-CG1 4.36Å; I226-V245 HydrophobicContact CG2-CG1 3.62Å; R233-V245 WeakPolarHBondContact O-CB 3.29Å; R233-V245 PolarHBondContact O-N 3.11Å; L235-V245 HydrophobicContact CD2-CG2 3.6Å; L235-V245 HydrophobicContact CG-CG2 3.8Å; V245-F266 HydrophobicContact CG1-CB 4Å; V245-F266 HydrophobicContact CG1-CD1 4.12Å; V245-F266 HydrophobicContact CG1-CD2 4.32Å; V245-F266 HydrophobicContact CG1-CG 3.88Å
246N97.1Very high96.2Very high60 Ų6040.1 Ų40.132%0.32123%0.232SC..  trans-104.4140-178.7-71.8-43.1000112.4L244 R264 F265 F266 S273L244-N246 WeakPolarHBondContact CB-ND2 3.42Å; L244-N246 PolarHBondContact O-N 3.44Å; N246-R264 HydrophobicContact CB-CB 4.33Å; N246-F265 CarbonylContact O-C 3.39Å; N246-F266 PolarHBondContact O-N 3.28Å; N246-S273 PolarHBondContact N-OG 3.33Å; N246-S273 PolarHBondContact O-OG 3.3Å; N246-S273 VanDerWaalsContact O-OG 3.07Å
247G97.6Very high96.3Very high13 Ų1336.9 Ų36.913%0.13421%0.209CC..SBendtrans85.4-157.2168.900000114.4I225 I226 R264I225-G247 WeakPolarHBondContact CA-O 2.96Å; I226-G247 PolarHBondContact N-O 2.83Å; G247-R264 WeakPolarHBondContact CA-O 3.31Å
248T97.9Very high96.3Very high1 Ų139.5 Ų39.51%0.00622%0.221CC..BIsolated β-bridgetrans-95.4-169.3-179.971.70000111.4A224 I225 G250 S252 F253 R264 F265 F266A224-T248 HydrophobicContact CB-CG2 4.04Å; A224-T248 WeakPolarHBondContact O-CA 3.32Å; A224-T248 WeakPolarHBondContact O-CB 3.42Å; I225-T248 HydrophobicContact CG1-CG2 4.07Å; T248-G250 VanDerWaalsContact C-N 3.29Å; T248-G250 PolarHBondContact OG1-N 3.18Å; T248-G250 VanDerWaalsContact OG1-N 3.13Å; T248-S252 WeakPolarHBondContact CB-O 3.27Å; T248-S252 WeakPolarHBondContact CG2-O 3.26Å; T248-S252 PolarHBondContact OG1-O 3.44Å; T248-F253 HydrophobicContact CG2-CD1 4.22Å; T248-R264 PolarHBondContact N-O 2.6Å; T248-F265 CarbonylContact O-C 3.54Å; T248-F265 VanDerWaalsContact O-CA 3.23Å; T248-F265 WeakPolarHBondContact O-CA 3.37Å; T248-F265 WeakPolarHBondContact O-CB 3.4Å; T248-F266 PolarHBondContact O-N 3.43Å
249D95.5Very high96.4Very high46 Ų4642.8 Ų42.825%0.24624%0.236CC..  trans-85.82170.265.41000113.4K100 Y113 A251K100-D249 IonicContact NZ-OD2 3.55Å; Y113-D249 PolarHBondContact OH-OD2 3.38Å; D249-A251 VanDerWaalsContact C-N 3.33Å; D249-A251 VanDerWaalsContact OD1-CB 3.29Å; D249-A251 WeakPolarHBondContact OD1-CB 3.42Å; D249-A251 PolarHBondContact OD1-N 2.83Å
250G94.9Very high96.5Very high8 Ų842.4 Ų42.48%0.08224%0.239CC..SBendtrans84.6-8.1-177.100000115.3T248 T379T248-G250 VanDerWaalsContact C-N 3.29Å; T248-G250 PolarHBondContact OG1-N 3.18Å; T248-G250 VanDerWaalsContact OG1-N 3.13Å; G250-T379 PolarHBondContact O-OG1 2.95Å
251A94.1Very high96.6Very high57 Ų5743.4 Ų43.447%0.47123%0.23SC..SBendtrans-77.1-31.2177.600000112.3D249 T379D249-A251 VanDerWaalsContact C-N 3.33Å; D249-A251 VanDerWaalsContact OD1-CB 3.29Å; D249-A251 WeakPolarHBondContact OD1-CB 3.42Å; D249-A251 PolarHBondContact OD1-N 2.83Å; A251-T379 VanDerWaalsContact O-CB 3.32Å; A251-T379 WeakPolarHBondContact O-CB 3.17Å; A251-T379 PolarHBondContact O-N 3.18Å; A251-T379 PolarHBondContact O-OG1 3.19Å
252S95.3Very high96.7Very high17 Ų1742.4 Ų42.412%0.11923%0.23CC..BIsolated β-bridgetrans-149.7162.5171.7600000111.1A224 T248 G377A224-S252 WeakPolarHBondContact CB-OG 3.32Å; T248-S252 WeakPolarHBondContact CB-O 3.27Å; T248-S252 WeakPolarHBondContact CG2-O 3.26Å; T248-S252 PolarHBondContact OG1-O 3.44Å; S252-G377 CarbonylContact C-O 3.44Å; S252-G377 WeakPolarHBondContact CA-O 3.4Å
253F97.7Very high96.7Very high6 Ų642.3 Ų42.33%0.02623%0.229CC..  trans-130.5163.6177-64.3-86.3000109.3T248 V257 L263 F265 L370 I372 G377T248-F253 HydrophobicContact CG2-CD1 4.22Å; F253-V257 HydrophobicContact CB-CG2 4.41Å; F253-L263 HydrophobicContact CD1-CB 4.08Å; F253-L263 HydrophobicContact CD1-CD1 4.26Å; F253-L263 HydrophobicContact CD1-CD2 4.11Å; F253-L263 HydrophobicContact CD1-CG 4.4Å; F253-L263 HydrophobicContact CD2-CD1 4.27Å; F253-L263 HydrophobicContact CE1-CB 3.78Å; F253-L263 HydrophobicContact CE1-CD1 4.39Å; F253-L263 HydrophobicContact CE2-CD1 4.4Å; F253-L263 HydrophobicContact CG-CD1 4.19Å; F253-L263 HydrophobicContact CG-CD2 4.42Å; F253-L263 HydrophobicContact CZ-CB 4.27Å; F253-L263 HydrophobicContact CZ-CD1 4.45Å; F253-F265 HydrophobicContact CE1-CB 4.27Å; F253-F265 HydrophobicContact CE1-CD1 4.26Å; F253-F265 HydrophobicContact CZ-CB 4.37Å; F253-F265 HydrophobicContact CZ-CD1 4.02Å; F253-F265 HydrophobicContact CZ-CG 4.48Å; F253-L370 HydrophobicContact CE2-CD1 4.37Å; F253-L370 HydrophobicContact CZ-CD1 4.14Å; F253-I372 HydrophobicContact CD2-CD1 3.51Å; F253-I372 HydrophobicContact CD2-CG1 4.16Å; F253-I372 HydrophobicContact CD2-CG2 4.47Å; F253-I372 HydrophobicContact CE2-CD1 3.41Å; F253-I372 VanDerWaalsContact CE2-CD1 3.41Å; F253-I372 HydrophobicContact CE2-CG1 4.16Å; F253-I372 HydrophobicContact CG-CD1 4.43Å; F253-I372 HydrophobicContact CZ-CD1 4.28Å; F253-G377 PolarHBondContact N-O 2.88Å
254P97.3Very high96.8Very high18 Ų1848.2 Ų48.212%0.11725%0.25CS..  trans-52.5143.4169.5-26.835.5000111.8S221 I225 V257S221-P254 WeakPolarHBondContact O-CB 3.43Å; S221-P254 WeakPolarHBondContact O-CG 3.41Å; I225-P254 HydrophobicContact CD1-CG 4.19Å; I225-P254 HydrophobicContact CG1-CG 4.27Å; P254-V257 WeakPolarHBondContact O-CG2 3.26Å
255P95.5Very high96.8Very high15 Ų1546.2 Ų46.210%0.09724%0.239CC..SBendtrans-66.4167.9-176.327.7-35000112.6I38 T42 I220 I375I38-P255 HydrophobicContact CG2-CB 4.14Å; T42-P255 HydrophobicContact CG2-CB 4.42Å; I220-P255 HydrophobicContact CD1-CG 4.46Å; I220-P255 HydrophobicContact CG1-CG 3.55Å; P255-I375 WeakPolarHBondContact CA-O 2.97Å; P255-I375 WeakPolarHBondContact CB-O 3.21Å
256F95.1Very high96.8Very high65 Ų6545.9 Ų45.929%0.28524%0.236SC..SBendtrans6345.5-178.7-42.2-75.6000113.7D35 I38 K39 K258 P374 I375D35-F256 HydrophobicContact CB-CZ 4.27Å; D35-F256 WeakPolarHBondContact OD1-CE1 3.37Å; I38-F256 HydrophobicContact CB-CZ 4.1Å; I38-F256 HydrophobicContact CG2-CE1 4.27Å; I38-F256 HydrophobicContact CG2-CE2 4.47Å; I38-F256 HydrophobicContact CG2-CZ 3.87Å; K39-F256 HydrophobicContact CD-CE2 4.46Å; K39-F256 HydrophobicContact CG-CE2 3.89Å; K39-F256 HydrophobicContact CG-CZ 4.24Å; F256-K258 PolarHBondContact O-N 3.41Å; F256-P374 CarbonylContact C-O 3.56Å; F256-P374 WeakPolarHBondContact CA-O 3.28Å; F256-P374 PolarHBondContact N-O 2.89Å; F256-P374 VanDerWaalsContact N-O 3.15Å; F256-I375 HydrophobicContact CE1-CG2 4.46Å; F256-I375 PolarHBondContact N-O 3.15Å
257V97.4Very high96.8Very high7 Ų743.7 Ų43.74%0.04223%0.226CC..  trans-62130.8179.2177.20000110.8F253 P254 L263 F292 I372 P374F253-V257 HydrophobicContact CB-CG2 4.41Å; P254-V257 WeakPolarHBondContact O-CG2 3.26Å; V257-L263 HydrophobicContact CG1-CD1 4.05Å; V257-L263 HydrophobicContact CG1-CD2 4.25Å; V257-F292 HydrophobicContact CG1-CE2 3.81Å; V257-F292 HydrophobicContact CG1-CZ 3.69Å; V257-I372 HydrophobicContact CG2-CG2 4.19Å; V257-P374 PolarHBondContact N-O 2.83Å
258K97.1Very high96.8Very high131 Ų13144 Ų4457%0.5723%0.226SC*.  trans-104.3157.8177.4-55.4179.4-178.9175.50111.5F256 D260 Q261F256-K258 PolarHBondContact O-N 3.41Å; K258-D260 WeakPolarHBondContact CB-OD1 3.45Å; K258-Q261 HydrophobicContact CB-CB 4.36Å; K258-Q261 WeakPolarHBondContact O-CB 3.44Å; K258-Q261 PolarHBondContact O-N 2.89Å
259K97.5Very high96.6Very high87 Ų8746.7 Ų46.738%0.37824%0.24SC..THydrogen-bonded Turntrans-73.1-28.2-179.2-61.5-177.8-177.51750113.7Q261 F278 K281 Y290K259-Q261 VanDerWaalsContact C-N 3.27Å; K259-F278 HydrophobicContact CB-CB 4.28Å; K259-F278 HydrophobicContact CB-CD1 4.02Å; K259-F278 HydrophobicContact CB-CD2 4.11Å; K259-F278 HydrophobicContact CB-CE1 4.44Å; K259-F278 HydrophobicContact CB-CG 3.85Å; K259-F278 HydrophobicContact CD-CD1 4.26Å; K259-F278 HydrophobicContact CD-CD2 4.44Å; K259-F278 HydrophobicContact CD-CE1 3.85Å; K259-F278 HydrophobicContact CD-CE2 4.04Å; K259-F278 HydrophobicContact CD-CZ 3.73Å; K259-F278 HydrophobicContact CG-CD1 4.29Å; K259-F278 HydrophobicContact CG-CD2 3.87Å; K259-F278 HydrophobicContact CG-CE1 4.27Å; K259-F278 HydrophobicContact CG-CE2 3.85Å; K259-F278 HydrophobicContact CG-CG 4.1Å; K259-F278 HydrophobicContact CG-CZ 4.06Å; K259-F278 WeakPolarHBondContact O-CB 3.37Å; K259-K281 VanDerWaalsContact NZ-CE 3.29Å; K259-Y290 HydrophobicContact CG-CD2 4.09Å; K259-Y290 HydrophobicContact CG-CE1 4.41Å; K259-Y290 HydrophobicContact CG-CE2 3.7Å
260D97.1Very high96.6Very high137 Ų13744.9 Ų44.973%0.73323%0.23SC*.THydrogen-bonded Turntrans-84-3.6177.561-31.6000112.7K258K258-D260 WeakPolarHBondContact CB-OD1 3.45Å
261Q95.8Very high96.7Very high72 Ų7244.9 Ų44.934%0.33623%0.229SC..  trans-80.2138.9180-170.8176.9-800111.2K258 K259 L263 F292K258-Q261 HydrophobicContact CB-CB 4.36Å; K258-Q261 WeakPolarHBondContact O-CB 3.44Å; K258-Q261 PolarHBondContact O-N 2.89Å; K259-Q261 VanDerWaalsContact C-N 3.27Å; Q261-L263 HydrophobicContact CG-CD2 3.97Å; Q261-F292 WeakPolarHBondContact O-CE1 3.26Å
262V97.8Very high96.9Very high60 Ų6042.8 Ų42.836%0.36421%0.209SC..  trans-90.6120.31671770000109Y275V262-Y275 HydrophobicContact CG1-CD2 3.63Å; V262-Y275 HydrophobicContact CG1-CG 3.9Å
263L98.2Very high97Very high3 Ų342.6 Ų42.62%0.01621%0.207CC..EExtended strand (participates in β ladder)trans-94.7108.8-178.9-63.9-175.1000110.3F253 V257 Q261 Y275 G276 F292 I372F253-L263 HydrophobicContact CD1-CB 4.08Å; F253-L263 HydrophobicContact CD1-CD1 4.26Å; F253-L263 HydrophobicContact CD1-CD2 4.11Å; F253-L263 HydrophobicContact CD1-CG 4.4Å; F253-L263 HydrophobicContact CD2-CD1 4.27Å; F253-L263 HydrophobicContact CE1-CB 3.78Å; F253-L263 HydrophobicContact CE1-CD1 4.39Å; F253-L263 HydrophobicContact CE2-CD1 4.4Å; F253-L263 HydrophobicContact CG-CD1 4.19Å; F253-L263 HydrophobicContact CG-CD2 4.42Å; F253-L263 HydrophobicContact CZ-CB 4.27Å; F253-L263 HydrophobicContact CZ-CD1 4.45Å; V257-L263 HydrophobicContact CG1-CD1 4.05Å; V257-L263 HydrophobicContact CG1-CD2 4.25Å; Q261-L263 HydrophobicContact CG-CD2 3.97Å; L263-Y275 CarbonylContact O-C 3.5Å; L263-Y275 WeakPolarHBondContact O-CA 3.19Å; L263-G276 PolarHBondContact N-O 2.62Å; L263-G276 VanDerWaalsContact N-O 3.08Å; L263-G276 PolarHBondContact O-N 2.92Å; L263-F292 HydrophobicContact CB-CD1 4.4Å; L263-F292 HydrophobicContact CD1-CD1 3.73Å; L263-F292 HydrophobicContact CD1-CD2 3.8Å; L263-F292 HydrophobicContact CD1-CE1 3.71Å; L263-F292 HydrophobicContact CD1-CE2 3.76Å; L263-F292 HydrophobicContact CD1-CG 3.79Å; L263-F292 HydrophobicContact CD1-CZ 3.72Å; L263-F292 HydrophobicContact CG-CD1 3.93Å; L263-F292 HydrophobicContact CG-CE1 3.74Å; L263-F292 HydrophobicContact CG-CG 4.47Å; L263-F292 HydrophobicContact CG-CZ 4.1Å; L263-I372 HydrophobicContact CD1-CD1 3.21Å
264R98.3Very high97Very high137 Ų13742.7 Ų42.752%0.51721%0.208SC..EExtended strand (participates in β ladder)trans-87.3142.4176.7-65.9-177177.981.7-0.5110.5N246 G247 T248 I274N246-R264 HydrophobicContact CB-CB 4.33Å; G247-R264 WeakPolarHBondContact CA-O 3.31Å; T248-R264 PolarHBondContact N-O 2.6Å; R264-I274 WeakPolarHBondContact CA-O 3.38Å
265F98.1Very high97Very high19 Ų1944.6 Ų44.68%0.08321%0.213CC..EExtended strand (participates in β ladder)trans-150.4149.4172.554.3-86000110.7N246 T248 F253 S273 I274 V294 L370N246-F265 CarbonylContact O-C 3.39Å; T248-F265 CarbonylContact O-C 3.54Å; T248-F265 VanDerWaalsContact O-CA 3.23Å; T248-F265 WeakPolarHBondContact O-CA 3.37Å; T248-F265 WeakPolarHBondContact O-CB 3.4Å; F253-F265 HydrophobicContact CE1-CB 4.27Å; F253-F265 HydrophobicContact CE1-CD1 4.26Å; F253-F265 HydrophobicContact CZ-CB 4.37Å; F253-F265 HydrophobicContact CZ-CD1 4.02Å; F253-F265 HydrophobicContact CZ-CG 4.48Å; F265-S273 WeakPolarHBondContact O-CA 3.35Å; F265-I274 HydrophobicContact CD2-CG2 3.75Å; F265-I274 HydrophobicContact CE1-CG2 4.18Å; F265-I274 HydrophobicContact CE2-CG2 3.22Å; F265-I274 HydrophobicContact CG-CG2 4.42Å; F265-I274 HydrophobicContact CZ-CG2 3.48Å; F265-I274 VanDerWaalsContact CZ-CG2 3.48Å; F265-I274 PolarHBondContact N-O 3.39Å; F265-I274 PolarHBondContact O-N 3Å; F265-I274 VanDerWaalsContact O-O 3.12Å; F265-V294 HydrophobicContact CZ-CG2 3.91Å; F265-L370 HydrophobicContact CD1-CD1 4.11Å; F265-L370 HydrophobicContact CE1-CD1 3.59Å; F265-L370 HydrophobicContact CZ-CD1 3.84Å
266F98.4Very high97.2Very high5 Ų543.9 Ų43.92%0.02221%0.209CC..EExtended strand (participates in β ladder)trans-95.5136175.9170.8-113.9000110.1Y211 I226 Y229 L235 V245 N246 T248 R272Y211-F266 HydrophobicContact CE1-CD1 4.06Å; Y211-F266 HydrophobicContact CE1-CE1 4.13Å; I226-F266 HydrophobicContact CD1-CB 3.76Å; I226-F266 HydrophobicContact CD1-CD1 3.97Å; I226-F266 HydrophobicContact CD1-CG 4.34Å; Y229-F266 AromaticContact CD1-CE1 3.94Å; Y229-F266 HydrophobicContact CD1-CE1 3.94Å; Y229-F266 AromaticContact CD1-CZ 3.89Å; Y229-F266 HydrophobicContact CD1-CZ 3.89Å; Y229-F266 AromaticContact CD2-CE1 3.83Å; Y229-F266 HydrophobicContact CD2-CE1 3.83Å; Y229-F266 HydrophobicContact CE1-CE1 4.19Å; Y229-F266 AromaticContact CE1-CZ 4Å; Y229-F266 HydrophobicContact CE1-CZ 4Å; Y229-F266 HydrophobicContact CE2-CE1 4.08Å; Y229-F266 AromaticContact CG-CE1 3.75Å; Y229-F266 HydrophobicContact CG-CE1 3.75Å; Y229-F266 HydrophobicContact CG-CZ 4.18Å; L235-F266 HydrophobicContact CD1-CD2 4.46Å; L235-F266 HydrophobicContact CD1-CE2 3.81Å; L235-F266 HydrophobicContact CD2-CE2 3.59Å; L235-F266 HydrophobicContact CD2-CZ 3.69Å; L235-F266 HydrophobicContact CG-CE2 4.3Å; V245-F266 HydrophobicContact CG1-CB 4Å; V245-F266 HydrophobicContact CG1-CD1 4.12Å; V245-F266 HydrophobicContact CG1-CD2 4.32Å; V245-F266 HydrophobicContact CG1-CG 3.88Å; N246-F266 PolarHBondContact O-N 3.28Å; T248-F266 PolarHBondContact O-N 3.43Å; F266-R272 WeakPolarHBondContact CD2-O 3.27Å
267S97.1Very high97.3Very high14 Ų1443 Ų4310%0.09821%0.209CC..EExtended strand (participates in β ladder)trans-126.1112.9169-175.30000110.7D269 I270 C271 R272 K384S267-D269 PolarHBondContact O-N 3.33Å; S267-I270 PolarHBondContact O-N 3.1Å; S267-C271 PolarHBondContact O-N 2.84Å; S267-C271 VanDerWaalsContact O-N 3.11Å; S267-R272 PolarHBondContact N-O 3.36Å; S267-K384 PolarHBondContact OG-NZ 2.94Å
268S96.3Very high97.4Very high19 Ų1945.4 Ų45.413%0.13322%0.219CC..G310 helixtrans-59.2-31.6176.654.10000113D208 Y211 I270 C271D208-S268 VanDerWaalsContact OD2-CB 3.26Å; D208-S268 WeakPolarHBondContact OD2-CB 3.41Å; D208-S268 PolarHBondContact OD2-OG 3.28Å; Y211-S268 PolarHBondContact OH-OG 3.46Å; S268-I270 VanDerWaalsContact C-N 3.29Å; S268-I270 PolarHBondContact O-N 2.89Å; S268-C271 PolarHBondContact O-N 3.25Å; S268-C271 PolarHBondContact O-SG 2.83Å
269D94.3Very high97.4Very high58 Ų5843.5 Ų43.531%0.3121%0.212SC..G310 helixtrans-60.7-34.9179.3-62.6-33.3000113.4S267 K384S267-D269 PolarHBondContact O-N 3.33Å; D269-K384 IonicContact OD2-NZ 3.95Å; D269-K384 PolarHBondContact OD2-NZ 3.43Å
270I96.5Very high97.4Very high7 Ų741 Ų414%0.03621%0.205CC..G310 helixtrans-106.94.1178.969171.9000112.8S267 S268 R272 I274 I329 I340 L386S267-I270 PolarHBondContact O-N 3.1Å; S268-I270 VanDerWaalsContact C-N 3.29Å; S268-I270 PolarHBondContact O-N 2.89Å; I270-R272 VanDerWaalsContact C-N 3.27Å; I270-R272 HydrophobicContact CD1-CG 3.96Å; I270-R272 HydrophobicContact CG1-CG 4.01Å; I270-R272 PolarHBondContact O-N 2.83Å; I270-I274 HydrophobicContact CD1-CD1 4.37Å; I270-I329 WeakPolarHBondContact O-CG2 3.22Å; I270-I340 HydrophobicContact CG2-CG1 4.39Å; I270-I340 HydrophobicContact CG2-CG2 3.85Å; I270-L386 HydrophobicContact CG2-CD1 3.84Å; I270-L386 HydrophobicContact CG2-CD2 3.78Å; I270-L386 HydrophobicContact CG2-CG 4.47Å
271C96.9Very high97.5Very high8 Ų841.1 Ų41.15%0.05420%0.2CC..THydrogen-bonded Turntrans5831.3172.7-51.50000115.1L235 Y237 W238 S267 S268 C332L235-C271 VanDerWaalsContact CD1-O 3.29Å; L235-C271 WeakPolarHBondContact CD1-O 3.5Å; Y237-C271 HydrophobicContact CD2-CB 4.06Å; Y237-C271 HydrophobicContact CE2-CB 4.24Å; W238-C271 PolarHBondContact NE1-O 2.88Å; S267-C271 PolarHBondContact O-N 2.84Å; S267-C271 VanDerWaalsContact O-N 3.11Å; S268-C271 PolarHBondContact O-N 3.25Å; S268-C271 PolarHBondContact O-SG 2.83Å; C271-C332 HydrophobicContact CB-CB 3.56Å; C271-C332 WeakPolarHBondContact CB-SG 3.39Å; C271-C332 WeakPolarHBondContact SG-CB 3.28Å; C271-C332 CovalentContact SG-SG 2Å; C271-C332 PolarHBondContact SG-SG 2.89Å
272R97.6Very high97.5Very high13 Ų1340.3 Ų40.35%0.04920%0.196CC..EExtended strand (participates in β ladder)trans-155.1164.7173.663.1171.6-75.1-174.4-4111.9F266 S267 I270 A298 F311 L327F266-R272 WeakPolarHBondContact CD2-O 3.27Å; S267-R272 PolarHBondContact N-O 3.36Å; I270-R272 VanDerWaalsContact C-N 3.27Å; I270-R272 HydrophobicContact CD1-CG 3.96Å; I270-R272 HydrophobicContact CG1-CG 4.01Å; I270-R272 PolarHBondContact O-N 2.83Å; R272-A298 PolarHBondContact NH1-O 3.44Å; R272-F311 HydrophobicContact CB-CE1 3.82Å; R272-F311 HydrophobicContact CB-CZ 4.28Å; R272-F311 HydrophobicContact CG-CE1 4.38Å; R272-F311 VanDerWaalsContact NH1-CE2 3.26Å; R272-L327 HydrophobicContact CG-CD2 4.01Å
273S98.1Very high97.5Very high13 Ų1342.6 Ų42.69%0.09121%0.21CC..EExtended strand (participates in β ladder)trans-80.7146.6161.1-73.50000111.7L244 N246 F265L244-S273 PolarHBondContact O-OG 3.22Å; N246-S273 PolarHBondContact N-OG 3.33Å; N246-S273 PolarHBondContact O-OG 3.3Å; N246-S273 VanDerWaalsContact O-OG 3.07Å; F265-S273 WeakPolarHBondContact O-CA 3.35Å
274I97Very high97.4Very high8 Ų843.1 Ų43.14%0.04121%0.213CC..EExtended strand (participates in β ladder)trans-138.2-178.9178-159.8160.6000109R264 F265 I270 V294 A298 F299R264-I274 WeakPolarHBondContact CA-O 3.38Å; F265-I274 HydrophobicContact CD2-CG2 3.75Å; F265-I274 HydrophobicContact CE1-CG2 4.18Å; F265-I274 HydrophobicContact CE2-CG2 3.22Å; F265-I274 HydrophobicContact CG-CG2 4.42Å; F265-I274 HydrophobicContact CZ-CG2 3.48Å; F265-I274 VanDerWaalsContact CZ-CG2 3.48Å; F265-I274 PolarHBondContact N-O 3.39Å; F265-I274 PolarHBondContact O-N 3Å; F265-I274 VanDerWaalsContact O-O 3.12Å; I270-I274 HydrophobicContact CD1-CD1 4.37Å; I274-V294 HydrophobicContact CD1-CG1 3.45Å; I274-V294 VanDerWaalsContact CD1-CG1 3.45Å; I274-V294 HydrophobicContact CG1-CG1 3.91Å; I274-A298 HydrophobicContact CD1-CB 3.95Å; I274-A298 HydrophobicContact CG1-CB 3.9Å; I274-F299 HydrophobicContact CD1-CE1 4.22Å; I274-F299 HydrophobicContact CD1-CE2 4.2Å; I274-F299 HydrophobicContact CD1-CZ 3.75Å
275Y98.1Very high97.2Very high58 Ų5840 Ų4023%0.22720%0.203CC..EExtended strand (participates in β ladder)trans-143.5153.4-177.564.3-82.5000112.2V262 L263 V277 P295 A298V262-Y275 HydrophobicContact CG1-CD2 3.63Å; V262-Y275 HydrophobicContact CG1-CG 3.9Å; L263-Y275 CarbonylContact O-C 3.5Å; L263-Y275 WeakPolarHBondContact O-CA 3.19Å; Y275-V277 HydrophobicContact CD2-CG1 3.99Å; Y275-V277 HydrophobicContact CE2-CG1 4.01Å; Y275-P295 HydrophobicContact CD2-CG 4.04Å; Y275-P295 HydrophobicContact CE2-CG 3.33Å; Y275-P295 WeakPolarHBondContact O-CD 3.14Å; Y275-A298 HydrophobicContact CE1-CB 3.93Å
276G97.9Very high97Very high1 Ų141.4 Ų41.41%0.0122%0.223CC..EExtended strand (participates in β ladder)trans-111.6148.3170.300000111.6L263 T293L263-G276 PolarHBondContact N-O 2.62Å; L263-G276 VanDerWaalsContact N-O 3.08Å; L263-G276 PolarHBondContact O-N 2.92Å; G276-T293 CarbonylContact C-O 3.52Å; G276-T293 VanDerWaalsContact CA-O 3.23Å; G276-T293 WeakPolarHBondContact CA-O 3.36Å
277V98.4Very high96.8Very high46 Ų4641.1 Ų41.128%0.27922%0.222SC..EExtended strand (participates in β ladder)trans-121.8146.3175.2-62.20000110.3Y275 Q279 F292 T293 P295Y275-V277 HydrophobicContact CD2-CG1 3.99Å; Y275-V277 HydrophobicContact CE2-CG1 4.01Å; V277-Q279 PolarHBondContact O-N 3.37Å; V277-F292 VanDerWaalsContact C-CD1 3.41Å; V277-F292 CarbonylContact O-C 3.51Å; V277-F292 VanDerWaalsContact O-CA 3.22Å; V277-F292 WeakPolarHBondContact O-CA 3.37Å; V277-T293 PolarHBondContact N-O 2.99Å; V277-T293 PolarHBondContact O-N 2.95Å; V277-P295 HydrophobicContact CG1-CG 4.15Å; V277-P295 HydrophobicContact CG2-CB 3.86Å; V277-P295 HydrophobicContact CG2-CG 4.04Å
278F98.6Very high96.7Very high57 Ų5743.5 Ų43.525%0.2524%0.237CC..EExtended strand (participates in β ladder)trans-63.2130.4-179.6176.3-94.8000111.1K259 S280 K281 Y290 F292K259-F278 HydrophobicContact CB-CB 4.28Å; K259-F278 HydrophobicContact CB-CD1 4.02Å; K259-F278 HydrophobicContact CB-CD2 4.11Å; K259-F278 HydrophobicContact CB-CE1 4.44Å; K259-F278 HydrophobicContact CB-CG 3.85Å; K259-F278 HydrophobicContact CD-CD1 4.26Å; K259-F278 HydrophobicContact CD-CD2 4.44Å; K259-F278 HydrophobicContact CD-CE1 3.85Å; K259-F278 HydrophobicContact CD-CE2 4.04Å; K259-F278 HydrophobicContact CD-CZ 3.73Å; K259-F278 HydrophobicContact CG-CD1 4.29Å; K259-F278 HydrophobicContact CG-CD2 3.87Å; K259-F278 HydrophobicContact CG-CE1 4.27Å; K259-F278 HydrophobicContact CG-CE2 3.85Å; K259-F278 HydrophobicContact CG-CG 4.1Å; K259-F278 HydrophobicContact CG-CZ 4.06Å; K259-F278 WeakPolarHBondContact O-CB 3.37Å; F278-S280 WeakPolarHBondContact CE2-O 3.08Å; F278-S280 VanDerWaalsContact CZ-C 3.46Å; F278-K281 HydrophobicContact CZ-CG 4.24Å; F278-Y290 HydrophobicContact CD2-CD2 4.48Å; F278-Y290 HydrophobicContact CD2-CG 4.09Å; F278-Y290 AromaticContact CE2-CD1 3.81Å; F278-Y290 HydrophobicContact CE2-CD1 3.81Å; F278-Y290 HydrophobicContact CE2-CD2 4.45Å; F278-Y290 HydrophobicContact CE2-CE1 4.49Å; F278-Y290 AromaticContact CE2-CG 3.78Å; F278-Y290 HydrophobicContact CE2-CG 3.78Å; F278-F292 HydrophobicContact CB-CD1 4.42Å; F278-F292 HydrophobicContact CB-CE1 4Å; F278-F292 HydrophobicContact CB-CZ 4.19Å; F278-F292 HydrophobicContact CD2-CE2 4.48Å
279Q97.6Very high96.8Very high91 Ų9142.7 Ų42.743%0.42523%0.232SC..EExtended strand (participates in β ladder)trans-112.5-52.7177.1-171.3-167.149.500110.9V277 R291 T293 E367V277-Q279 PolarHBondContact O-N 3.37Å; Q279-R291 HydrophobicContact CB-CG 4.46Å; Q279-R291 PolarHBondContact N-O 3.16Å; Q279-R291 VanDerWaalsContact OE1-CD 3.25Å; Q279-T293 HydrophobicContact CB-CG2 4.07Å; Q279-T293 HydrophobicContact CG-CG2 4.35Å; Q279-E367 PolarHBondContact NE2-OE2 3.35Å
280S97.9Very high97Very high34 Ų3442.4 Ų42.424%0.23823%0.226CC..EExtended strand (participates in β ladder)trans-156166.8-17260.20000113.3F278 Q282 R291F278-S280 WeakPolarHBondContact CE2-O 3.08Å; F278-S280 VanDerWaalsContact CZ-C 3.46Å; S280-Q282 PolarHBondContact OG-NE2 3.1Å; S280-R291 WeakPolarHBondContact O-CB 3.38Å; S280-R291 PolarHBondContact O-N 2.8Å
281K98.2Very high97.1Very high141 Ų14143.9 Ų43.961%0.61323%0.231SC*.EExtended strand (participates in β ladder)trans-89.1138.8168.5-67.2-174.3-179.8-177.30109.3K259 F278 L289 Y290K259-K281 VanDerWaalsContact NZ-CE 3.29Å; F278-K281 HydrophobicContact CZ-CG 4.24Å; K281-L289 WeakPolarHBondContact CA-O 3.14Å; K281-Y290 HydrophobicContact CG-CD1 4.26Å; K281-Y290 HydrophobicContact CG-CE1 4.21Å
282Q97.5Very high97.2Very high55 Ų5543.5 Ų43.526%0.25723%0.229SC..EExtended strand (participates in β ladder)trans-123.1157.3176.8-61.8-59.9-35.800110.2S280 L289 R291S280-Q282 PolarHBondContact OG-NE2 3.1Å; Q282-L289 HydrophobicContact CB-CB 4.37Å; Q282-L289 PolarHBondContact N-O 3.33Å; Q282-L289 PolarHBondContact O-N 2.79Å; Q282-R291 HydrophobicContact CG-CB 3.82Å
283T96.9Very high97.2Very high107 Ų10743.5 Ų43.566%0.65623%0.231SC*.EExtended strand (participates in β ladder)trans-128.2115170.2-58.80000108.5I287T283-I287 WeakPolarHBondContact CA-O 3.36Å
284V95.4Very high97.2Very high15 Ų1543.6 Ų43.69%0.09123%0.231CC..EExtended strand (participates in β ladder)trans-120119.3-177.9179.20000108.1G286 I287 L289 V420 I421V284-G286 PolarHBondContact O-N 2.92Å; V284-G286 VanDerWaalsContact O-N 3.12Å; V284-I287 PolarHBondContact N-O 3.3Å; V284-I287 WeakPolarHBondContact O-CB 3.22Å; V284-I287 PolarHBondContact O-N 2.93Å; V284-L289 HydrophobicContact CB-CD1 3.78Å; V284-L289 HydrophobicContact CG2-CD1 3.63Å; V284-V420 HydrophobicContact CG1-CG1 3.89Å; V284-I421 HydrophobicContact CG1-CG2 4.35Å
285K94.5Very high97.2Very high70 Ų7044 Ų4430%0.30423%0.234SC..THydrogen-bonded Turntrans50.240.3-179.1-56.6-172.1176.2-163.30112.6I287 I421 D423 A426 R430K285-I287 VanDerWaalsContact C-N 3.3Å; K285-I287 PolarHBondContact O-N 3.27Å; K285-I421 HydrophobicContact CD-CG2 4.3Å; K285-I421 VanDerWaalsContact CD-O 3.24Å; K285-I421 WeakPolarHBondContact CD-O 3.38Å; K285-I421 WeakPolarHBondContact CE-O 3.43Å; K285-I421 PolarHBondContact NZ-O 3.46Å; K285-D423 VanDerWaalsContact CD-OD1 3.27Å; K285-D423 WeakPolarHBondContact CD-OD1 3.32Å; K285-D423 WeakPolarHBondContact CE-OD1 3.4Å; K285-D423 IonicContact NZ-OD1 3.49Å; K285-D423 PolarHBondContact NZ-OD1 3.06Å; K285-D423 IonicContact NZ-OD2 3.09Å; K285-D423 PolarHBondContact NZ-OD2 3.25Å; K285-A426 HydrophobicContact CB-CB 3.84Å; K285-A426 HydrophobicContact CD-CB 3.88Å; K285-R430 PolarHBondContact O-NH1 2.81Å
286G93.4Very high97.1Very high49 Ų4946.1 Ų46.151%0.50524%0.241SC..THydrogen-bonded Turntrans74.610.2-179.400000115.5V284V284-G286 PolarHBondContact O-N 2.92Å; V284-G286 VanDerWaalsContact O-N 3.12Å
287I94.9Very high97.1Very high0 Ų050.9 Ų50.90%026%0.263CS..EExtended strand (participates in β ladder)trans-104.5124.4176.8-54.9165.6000108.5T283 V284 K285 L289 E373 L380 I421 A426 F429 R430T283-I287 WeakPolarHBondContact CA-O 3.36Å; V284-I287 PolarHBondContact N-O 3.3Å; V284-I287 WeakPolarHBondContact O-CB 3.22Å; V284-I287 PolarHBondContact O-N 2.93Å; K285-I287 VanDerWaalsContact C-N 3.3Å; K285-I287 PolarHBondContact O-N 3.27Å; I287-L289 HydrophobicContact CG2-CD2 3.82Å; I287-E373 HydrophobicContact CG2-CG 3.92Å; I287-L380 HydrophobicContact CD1-CD1 3.98Å; I287-L380 HydrophobicContact CG2-CD1 4.03Å; I287-I421 HydrophobicContact CD1-CD1 4.37Å; I287-A426 HydrophobicContact CD1-CB 4.08Å; I287-F429 HydrophobicContact CD1-CB 4.18Å; I287-F429 HydrophobicContact CD1-CD1 3.67Å; I287-F429 HydrophobicContact CD1-CE1 4.47Å; I287-F429 HydrophobicContact CD1-CG 4.18Å; I287-F429 HydrophobicContact CG1-CD1 4.16Å; I287-F429 HydrophobicContact CG2-CD1 4.1Å; I287-F429 HydrophobicContact CG2-CE1 3.87Å; I287-R430 HydrophobicContact CD1-CG 4.31Å; I287-R430 HydrophobicContact CG1-CG 3.69Å
288P95.9Very high97Very high64 Ų6448.7 Ų48.742%0.41625%0.25SC..EExtended strand (participates in β ladder)trans-75.4128.4176.629.9-33000110.9
289L97.6Very high96.8Very high2 Ų246.9 Ų46.91%0.0124%0.242CC..EExtended strand (participates in β ladder)trans-127.3159.5-177.1-51.7179.5000111.4K281 Q282 V284 I287 D371 I372 E373 L380K281-L289 WeakPolarHBondContact CA-O 3.14Å; Q282-L289 HydrophobicContact CB-CB 4.37Å; Q282-L289 PolarHBondContact N-O 3.33Å; Q282-L289 PolarHBondContact O-N 2.79Å; V284-L289 HydrophobicContact CB-CD1 3.78Å; V284-L289 HydrophobicContact CG2-CD1 3.63Å; I287-L289 HydrophobicContact CG2-CD2 3.82Å; L289-D371 HydrophobicContact CB-CB 4.12Å; L289-D371 HydrophobicContact CD1-CB 3.67Å; L289-I372 CarbonylContact C-O 3.55Å; L289-I372 WeakPolarHBondContact CA-O 3.18Å; L289-E373 HydrophobicContact CD2-CB 3.59Å; L289-E373 HydrophobicContact CD2-CG 4.04Å; L289-L380 HydrophobicContact CD1-CB 4.1Å; L289-L380 HydrophobicContact CD2-CB 4.26Å; L289-L380 HydrophobicContact CD2-CD1 3.93Å; L289-L380 HydrophobicContact CD2-CG 4.2Å
290Y98.6Very high96.8Very high51 Ų5142.9 Ų42.920%0.222%0.224CC..EExtended strand (participates in β ladder)trans-104.8122.3168.2-70.2-10.5000109.6K259 F278 K281 F292 D371 I372 P374K259-Y290 HydrophobicContact CG-CD2 4.09Å; K259-Y290 HydrophobicContact CG-CE1 4.41Å; K259-Y290 HydrophobicContact CG-CE2 3.7Å; F278-Y290 HydrophobicContact CD2-CD2 4.48Å; F278-Y290 HydrophobicContact CD2-CG 4.09Å; F278-Y290 AromaticContact CE2-CD1 3.81Å; F278-Y290 HydrophobicContact CE2-CD1 3.81Å; F278-Y290 HydrophobicContact CE2-CD2 4.45Å; F278-Y290 HydrophobicContact CE2-CE1 4.49Å; F278-Y290 AromaticContact CE2-CG 3.78Å; F278-Y290 HydrophobicContact CE2-CG 3.78Å; K281-Y290 HydrophobicContact CG-CD1 4.26Å; K281-Y290 HydrophobicContact CG-CE1 4.21Å; Y290-F292 HydrophobicContact CD2-CE2 4.43Å; Y290-D371 WeakPolarHBondContact O-CA 3.22Å; Y290-I372 PolarHBondContact N-O 3.38Å; Y290-I372 PolarHBondContact O-N 2.9Å; Y290-P374 HydrophobicContact CD2-CB 3.8Å; Y290-P374 HydrophobicContact CD2-CG 4.48Å; Y290-P374 HydrophobicContact CE1-CG 4.44Å; Y290-P374 HydrophobicContact CE2-CB 3.58Å; Y290-P374 HydrophobicContact CE2-CG 4.24Å; Y290-P374 HydrophobicContact CG-CB 4.41Å
291R98.6Very high96.7Very high38 Ų3841.4 Ų41.414%0.14321%0.214CC..EExtended strand (participates in β ladder)trans-80.5118.9172.8180157.6-68.1-179.11.8109.7Q279 S280 Q282 T293 F369 D371Q279-R291 HydrophobicContact CB-CG 4.46Å; Q279-R291 PolarHBondContact N-O 3.16Å; Q279-R291 VanDerWaalsContact OE1-CD 3.25Å; S280-R291 WeakPolarHBondContact O-CB 3.38Å; S280-R291 PolarHBondContact O-N 2.8Å; Q282-R291 HydrophobicContact CG-CB 3.82Å; R291-T293 HydrophobicContact CG-CG2 4.06Å; R291-F369 HydrophobicContact CG-CB 4.15Å; R291-D371 VanDerWaalsContact CA-OD1 3.3Å; R291-D371 WeakPolarHBondContact CA-OD1 3.27Å; R291-D371 WeakPolarHBondContact CB-OD1 3.31Å; R291-D371 WeakPolarHBondContact CG-OD1 3.41Å; R291-D371 IonicContact CZ-OD1 3.8Å; R291-D371 IonicContact CZ-OD2 3.07Å; R291-D371 IonicContact NE-OD1 3.27Å; R291-D371 PolarHBondContact NE-OD1 2.94Å; R291-D371 IonicContact NE-OD2 2.86Å; R291-D371 IonicContact NH2-OD1 2.82Å; R291-D371 IonicContact NH2-OD2 3.42Å; R291-D371 PolarHBondContact NH2-OD2 3.39Å
292F98.6Very high96.6Very high1 Ų136.1 Ų36.10%0.00419%0.194CC..EExtended strand (participates in β ladder)trans-106.8127.8168.5-74.5-100.1000109.3V257 Q261 L263 V277 F278 Y290 F369 L370 I372V257-F292 HydrophobicContact CG1-CE2 3.81Å; V257-F292 HydrophobicContact CG1-CZ 3.69Å; Q261-F292 WeakPolarHBondContact O-CE1 3.26Å; L263-F292 HydrophobicContact CB-CD1 4.4Å; L263-F292 HydrophobicContact CD1-CD1 3.73Å; L263-F292 HydrophobicContact CD1-CD2 3.8Å; L263-F292 HydrophobicContact CD1-CE1 3.71Å; L263-F292 HydrophobicContact CD1-CE2 3.76Å; L263-F292 HydrophobicContact CD1-CG 3.79Å; L263-F292 HydrophobicContact CD1-CZ 3.72Å; L263-F292 HydrophobicContact CG-CD1 3.93Å; L263-F292 HydrophobicContact CG-CE1 3.74Å; L263-F292 HydrophobicContact CG-CG 4.47Å; L263-F292 HydrophobicContact CG-CZ 4.1Å; V277-F292 VanDerWaalsContact C-CD1 3.41Å; V277-F292 CarbonylContact O-C 3.51Å; V277-F292 VanDerWaalsContact O-CA 3.22Å; V277-F292 WeakPolarHBondContact O-CA 3.37Å; F278-F292 HydrophobicContact CB-CD1 4.42Å; F278-F292 HydrophobicContact CB-CE1 4Å; F278-F292 HydrophobicContact CB-CZ 4.19Å; F278-F292 HydrophobicContact CD2-CE2 4.48Å; Y290-F292 HydrophobicContact CD2-CE2 4.43Å; F292-F369 CarbonylContact O-C 3.58Å; F292-F369 VanDerWaalsContact O-CA 3.29Å; F292-F369 WeakPolarHBondContact O-CA 3.35Å; F292-L370 PolarHBondContact N-O 2.75Å; F292-L370 PolarHBondContact O-N 2.88Å; F292-I372 HydrophobicContact CB-CD1 4.44Å; F292-I372 HydrophobicContact CD2-CD1 3.76Å; F292-I372 HydrophobicContact CD2-CG1 4.47Å; F292-I372 HydrophobicContact CE2-CD1 4.32Å; F292-I372 HydrophobicContact CG-CD1 4.25Å
293T98Very high96.5Very high13 Ų1337 Ų378%0.0821%0.211CC..EExtended strand (participates in β ladder)trans-111.6150.6176.457.90000110.6G276 V277 Q279 R291 P295 T368 F369G276-T293 CarbonylContact C-O 3.52Å; G276-T293 VanDerWaalsContact CA-O 3.23Å; G276-T293 WeakPolarHBondContact CA-O 3.36Å; V277-T293 PolarHBondContact N-O 2.99Å; V277-T293 PolarHBondContact O-N 2.95Å; Q279-T293 HydrophobicContact CB-CG2 4.07Å; Q279-T293 HydrophobicContact CG-CG2 4.35Å; R291-T293 HydrophobicContact CG-CG2 4.06Å; T293-P295 WeakPolarHBondContact O-CD 3.46Å; T293-T368 WeakPolarHBondContact CA-O 3.29Å; T293-F369 HydrophobicContact CG2-CB 3.9Å
294V97.3Very high96.5Very high15 Ų1536.9 Ų36.99%0.09120%0.203CC..  trans-74.9115.7169.2177.50000107.6F265 I274 A298 F299 T368F265-V294 HydrophobicContact CZ-CG2 3.91Å; I274-V294 HydrophobicContact CD1-CG1 3.45Å; I274-V294 VanDerWaalsContact CD1-CG1 3.45Å; I274-V294 HydrophobicContact CG1-CG1 3.91Å; V294-A298 HydrophobicContact CG1-CB 3.83Å; V294-F299 HydrophobicContact CG1-CD2 4.37Å; V294-F299 HydrophobicContact CG1-CE2 3.53Å; V294-F299 HydrophobicContact CG1-CZ 4.13Å; V294-T368 HydrophobicContact CG2-CG2 3.84Å; V294-T368 PolarHBondContact N-O 3.33Å; V294-T368 VanDerWaalsContact N-O 3.11Å
295P96.8Very high96.5Very high16 Ų1637.8 Ų37.810%0.10421%0.208CC..  trans-77158.2-173.232.9-35000111.6Y275 V277 T293 E297 A298Y275-P295 HydrophobicContact CD2-CG 4.04Å; Y275-P295 HydrophobicContact CE2-CG 3.33Å; Y275-P295 WeakPolarHBondContact O-CD 3.14Å; V277-P295 HydrophobicContact CG1-CG 4.15Å; V277-P295 HydrophobicContact CG2-CB 3.86Å; V277-P295 HydrophobicContact CG2-CG 4.04Å; T293-P295 WeakPolarHBondContact O-CD 3.46Å; P295-E297 WeakPolarHBondContact CB-OE2 3.19Å; P295-E297 PolarHBondContact O-N 2.84Å; P295-E297 VanDerWaalsContact O-N 3.16Å; P295-A298 VanDerWaalsContact O-CB 3.29Å; P295-A298 WeakPolarHBondContact O-CB 3.4Å; P295-A298 PolarHBondContact O-N 3.11Å
296R96.4Very high96.6Very high103 Ų10342.6 Ų42.639%0.38923%0.229SC..G310 helixtrans-53.1-37.6177.3164.6177156.2124.46.9111.8A298 F299 A300 E304 H347R296-A298 PolarHBondContact O-N 2.92Å; R296-A298 VanDerWaalsContact O-N 3.14Å; R296-F299 CarbonylContact O-C 3.51Å; R296-F299 PolarHBondContact O-N 3.01Å; R296-A300 PolarHBondContact O-N 2.81Å; R296-A300 VanDerWaalsContact O-N 3.12Å; R296-E304 IonicContact CZ-OE2 2.81Å; R296-E304 IonicContact NE-OE2 3.12Å; R296-E304 VanDerWaalsContact NH2-CD 3.3Å; R296-E304 IonicContact NH2-OE1 2.63Å; R296-E304 PolarHBondContact NH2-OE1 3.26Å; R296-E304 IonicContact NH2-OE2 2.63Å; R296-E304 PolarHBondContact NH2-OE2 3.33Å; R296-H347 HydrophobicContact CB-CB 4.34Å; R296-H347 HydrophobicContact CG-CB 3.96Å
297E97.3Very high96.8Very high100 Ų10045.6 Ų45.647%0.46723%0.234SC..G310 helixtrans-57.4-26.6179.9-68.883170.500112.8P295 F299 A300 V305 N308P295-E297 WeakPolarHBondContact CB-OE2 3.19Å; P295-E297 PolarHBondContact O-N 2.84Å; P295-E297 VanDerWaalsContact O-N 3.16Å; E297-F299 PolarHBondContact O-N 3.02Å; E297-A300 PolarHBondContact O-N 3.28Å; E297-V305 HydrophobicContact CB-CG2 4.06Å; E297-V305 HydrophobicContact CG-CG2 4.18Å; E297-N308 PolarHBondContact O-ND2 2.82Å
298A96.4Very high96.9Very high0 Ų046.3 Ų46.30%024%0.238CC..G310 helixtrans-66.7-22.7175.600000113.2R272 I274 Y275 V294 P295 R296R272-A298 PolarHBondContact NH1-O 3.44Å; I274-A298 HydrophobicContact CD1-CB 3.95Å; I274-A298 HydrophobicContact CG1-CB 3.9Å; Y275-A298 HydrophobicContact CE1-CB 3.93Å; V294-A298 HydrophobicContact CG1-CB 3.83Å; P295-A298 VanDerWaalsContact O-CB 3.29Å; P295-A298 WeakPolarHBondContact O-CB 3.4Å; P295-A298 PolarHBondContact O-N 3.11Å; R296-A298 PolarHBondContact O-N 2.92Å; R296-A298 VanDerWaalsContact O-N 3.14Å
299F95.6Very high96.9Very high19 Ų1948.8 Ų48.88%0.08324%0.24CC..G310 helixtrans-114.84.4178-56.3-79.9000113.2I274 V294 R296 E297 G325 L342I274-F299 HydrophobicContact CD1-CE1 4.22Å; I274-F299 HydrophobicContact CD1-CE2 4.2Å; I274-F299 HydrophobicContact CD1-CZ 3.75Å; V294-F299 HydrophobicContact CG1-CD2 4.37Å; V294-F299 HydrophobicContact CG1-CE2 3.53Å; V294-F299 HydrophobicContact CG1-CZ 4.13Å; R296-F299 CarbonylContact O-C 3.51Å; R296-F299 PolarHBondContact O-N 3.01Å; E297-F299 PolarHBondContact O-N 3.02Å; F299-G325 PolarHBondContact O-N 3.33Å; F299-L342 HydrophobicContact CD2-CD1 4.25Å; F299-L342 HydrophobicContact CD2-CG 4.38Å; F299-L342 HydrophobicContact CE2-CD1 4.06Å; F299-L342 HydrophobicContact CE2-CD2 3.95Å; F299-L342 HydrophobicContact CE2-CG 3.98Å; F299-L342 HydrophobicContact CZ-CD2 4.04Å; F299-L342 HydrophobicContact CZ-CG 4.31Å
300A97.1Very high96.8Very high7 Ų749.1 Ų49.16%0.05824%0.242CC..  trans-69.5154.2179.900000111.8R296 E297 E304 V305 N308R296-A300 PolarHBondContact O-N 2.81Å; R296-A300 VanDerWaalsContact O-N 3.12Å; E297-A300 PolarHBondContact O-N 3.28Å; A300-E304 HydrophobicContact CB-CB 4.09Å; A300-V305 HydrophobicContact CB-CB 4.22Å; A300-V305 HydrophobicContact CB-CG2 3.71Å; A300-N308 PolarHBondContact O-ND2 3.31Å
301S96.9Very high96.7Very high4 Ų447.8 Ų47.83%0.02824%0.237CC..  trans-72.2159.3178.370.60000111.6A303 E304 V305 T322 L323S301-A303 PolarHBondContact O-N 3.3Å; S301-A303 VanDerWaalsContact O-N 3.1Å; S301-E304 PolarHBondContact O-N 3.27Å; S301-V305 PolarHBondContact O-N 3.26Å; S301-T322 WeakPolarHBondContact CB-O 3.45Å; S301-T322 PolarHBondContact OG-O 3.13Å; S301-T322 VanDerWaalsContact OG-O 3.11Å; S301-L323 VanDerWaalsContact CB-O 3.3Å; S301-L323 WeakPolarHBondContact CB-O 3.27Å
302P95.6Very high96.6Very high29 Ų2947.3 Ų47.319%0.18824%0.239CC..THydrogen-bonded Turntrans-55.8-22.9172.5-29.937.2000115.1E304 V305 K306 C312 C321P302-E304 VanDerWaalsContact C-N 3.34Å; P302-V305 WeakPolarHBondContact CA-O 3.25Å; P302-K306 WeakPolarHBondContact O-CA 3.43Å; P302-C312 HydrophobicContact CG-CB 4.29Å; P302-C321 HydrophobicContact CB-CB 4.4Å; P302-C321 WeakPolarHBondContact CD-O 3.48Å; P302-C321 HydrophobicContact CG-CB 3.98Å
303A95.1Very high96.3Very high74 Ų7450.6 Ų50.661%0.61226%0.26SS*.THydrogen-bonded Turntrans-68.4-32.8173.600000112.6S301 T322S301-A303 PolarHBondContact O-N 3.3Å; S301-A303 VanDerWaalsContact O-N 3.1Å; A303-T322 HydrophobicContact CB-CG2 4.44Å
304E95.7Very high96Very high104 Ų10452.5 Ų52.549%0.48627%0.269SS..THydrogen-bonded Turntrans-91-47.6176.4-66.4-179.6-156.800111.5R296 A300 S301 P302R296-E304 IonicContact CZ-OE2 2.81Å; R296-E304 IonicContact NE-OE2 3.12Å; R296-E304 VanDerWaalsContact NH2-CD 3.3Å; R296-E304 IonicContact NH2-OE1 2.63Å; R296-E304 PolarHBondContact NH2-OE1 3.26Å; R296-E304 IonicContact NH2-OE2 2.63Å; R296-E304 PolarHBondContact NH2-OE2 3.33Å; A300-E304 HydrophobicContact CB-CB 4.09Å; S301-E304 PolarHBondContact O-N 3.27Å; P302-E304 VanDerWaalsContact C-N 3.34Å
305V97.3Very high95.8Very high34 Ų3458.8 Ų58.821%0.20629%0.292CS..  trans-125.697.7-177.6179.10000109.1E297 A300 S301 P302 D307 N308E297-V305 HydrophobicContact CB-CG2 4.06Å; E297-V305 HydrophobicContact CG-CG2 4.18Å; A300-V305 HydrophobicContact CB-CB 4.22Å; A300-V305 HydrophobicContact CB-CG2 3.71Å; S301-V305 PolarHBondContact O-N 3.26Å; P302-V305 WeakPolarHBondContact CA-O 3.25Å; V305-D307 HydrophobicContact CG1-CB 4.4Å; V305-D307 PolarHBondContact O-N 2.63Å; V305-D307 VanDerWaalsContact O-N 3.08Å; V305-N308 WeakPolarHBondContact O-CB 3.22Å; V305-N308 PolarHBondContact O-N 2.77Å
306K96.7Very high95.6Very high172 Ų17264 Ų6475%0.74832%0.323SS*.G310 helixtrans-53-35.9-175.1-67.4-175.5-179.2179.30113.4P302 N308 Y309P302-K306 WeakPolarHBondContact O-CA 3.43Å; K306-N308 PolarHBondContact O-N 3.07Å; K306-N308 VanDerWaalsContact O-N 3.09Å; K306-Y309 WeakPolarHBondContact O-CB 3.05Å; K306-Y309 VanDerWaalsContact O-CD1 3.32Å; K306-Y309 WeakPolarHBondContact O-CD1 3.25Å; K306-Y309 PolarHBondContact O-N 3.22Å; K306-Y309 VanDerWaalsContact O-N 3.08Å
307D96.3Very high95.4Very high112 Ų11260.4 Ų60.460%0.59931%0.312SS*.G310 helixtrans-62.6-16.2-178.8-70.9-10.8000114H241 V305 Y309H241-D307 PolarHBondContact CE1-O 2.87Å; H241-D307 VanDerWaalsContact CE1-O 3.32Å; H241-D307 PolarHBondContact NE2-O 3.12Å; V305-D307 HydrophobicContact CG1-CB 4.4Å; V305-D307 PolarHBondContact O-N 2.63Å; V305-D307 VanDerWaalsContact O-N 3.08Å; D307-Y309 VanDerWaalsContact C-N 3.28Å; D307-Y309 PolarHBondContact O-N 2.73Å
308N97.2Very high95.2Very high15 Ų1556.5 Ų56.58%0.0830%0.296CS..G310 helixtrans-83.32.1176.6-70.4-20.2000113.4E297 A300 V305 K306 C310 F311E297-N308 PolarHBondContact O-ND2 2.82Å; A300-N308 PolarHBondContact O-ND2 3.31Å; V305-N308 WeakPolarHBondContact O-CB 3.22Å; V305-N308 PolarHBondContact O-N 2.77Å; K306-N308 PolarHBondContact O-N 3.07Å; K306-N308 VanDerWaalsContact O-N 3.09Å; N308-C310 PolarHBondContact O-N 2.77Å; N308-C310 VanDerWaalsContact O-N 3.14Å; N308-F311 HydrophobicContact CB-CD2 4.4Å; N308-F311 PolarHBondContact O-N 2.63Å
309Y96.1Very high95Very high116 Ų11661.8 Ų61.846%0.45532%0.32SS..G310 helixtrans-51.1-40.6-176.877.8-91.4000113.3H241 K306 D307 F311 C312H241-Y309 AromaticContact CE1-CE1 3.65Å; K306-Y309 WeakPolarHBondContact O-CB 3.05Å; K306-Y309 VanDerWaalsContact O-CD1 3.32Å; K306-Y309 WeakPolarHBondContact O-CD1 3.25Å; K306-Y309 PolarHBondContact O-N 3.22Å; K306-Y309 VanDerWaalsContact O-N 3.08Å; D307-Y309 VanDerWaalsContact C-N 3.28Å; D307-Y309 PolarHBondContact O-N 2.73Å; Y309-F311 PolarHBondContact O-N 2.73Å; Y309-C312 WeakPolarHBondContact O-CB 3.24Å; Y309-C312 PolarHBondContact O-N 3.29Å; Y309-C312 VanDerWaalsContact O-N 3.11Å
310C96.5Very high95Very high9 Ų966.5 Ų66.56%0.06135%0.346CS..G310 helixtrans-78.2-1.1-176.840.80000114.6E239 H241 C242 N308E239-C310 HydrophobicContact CB-CB 4.14Å; E239-C310 WeakPolarHBondContact O-CB 3.43Å; E239-C310 PolarHBondContact O-SG 3.43Å; E239-C310 VanDerWaalsContact O-SG 3.4Å; H241-C310 VanDerWaalsContact CE1-SG 3.52Å; C242-C310 HydrophobicContact CB-CB 3.66Å; C242-C310 WeakPolarHBondContact CB-SG 3.31Å; C242-C310 VanDerWaalsContact SG-C 3.54Å; C242-C310 VanDerWaalsContact SG-CA 3.6Å; C242-C310 WeakPolarHBondContact SG-CB 3.46Å; C242-C310 CovalentContact SG-SG 2.02Å; C242-C310 PolarHBondContact SG-SG 2.82Å; N308-C310 PolarHBondContact O-N 2.77Å; N308-C310 VanDerWaalsContact O-N 3.14Å
311F96.6Very high94.9Very high23 Ų2366.7 Ų66.710%0.10135%0.347CS..G310 helixtrans-93.5-7.2167.1-64.9-62.8000112.9W238 C242 R272 N308 Y309 T313 L327W238-F311 AromaticContact CD2-CD1 3.56Å; W238-F311 HydrophobicContact CD2-CD1 3.56Å; W238-F311 AromaticContact CD2-CE1 3.81Å; W238-F311 HydrophobicContact CD2-CE1 3.81Å; W238-F311 AromaticContact CE2-CD1 3.76Å; W238-F311 AromaticContact CE2-CE1 3.83Å; W238-F311 AromaticContact CE3-CD1 3.61Å; W238-F311 HydrophobicContact CE3-CD1 3.61Å; W238-F311 HydrophobicContact CE3-CE1 4.33Å; W238-F311 HydrophobicContact CG-CD1 4.11Å; W238-F311 AromaticContact CG-CE1 3.93Å; W238-F311 HydrophobicContact CG-CE1 3.93Å; W238-F311 AromaticContact CH2-CD1 3.98Å; W238-F311 HydrophobicContact CH2-CD1 3.98Å; W238-F311 AromaticContact CZ2-CD1 3.98Å; W238-F311 HydrophobicContact CZ2-CD1 3.98Å; W238-F311 HydrophobicContact CZ2-CE1 4.34Å; W238-F311 HydrophobicContact CZ3-CB 4.3Å; W238-F311 AromaticContact CZ3-CD1 3.82Å; W238-F311 HydrophobicContact CZ3-CD1 3.82Å; W238-F311 AromaticContact NE1-CE1 3.99Å; C242-F311 HydrophobicContact CB-CD1 3.98Å; C242-F311 HydrophobicContact CB-CD2 4.26Å; C242-F311 HydrophobicContact CB-CE1 3.49Å; C242-F311 VanDerWaalsContact CB-CE1 3.49Å; C242-F311 HydrophobicContact CB-CE2 3.78Å; C242-F311 HydrophobicContact CB-CG 4.33Å; C242-F311 HydrophobicContact CB-CZ 3.37Å; C242-F311 WeakPolarHBondContact SG-CD2 3.5Å; C242-F311 WeakPolarHBondContact SG-CE2 3.45Å; C242-F311 VanDerWaalsContact SG-CZ 3.52Å; R272-F311 HydrophobicContact CB-CE1 3.82Å; R272-F311 HydrophobicContact CB-CZ 4.28Å; R272-F311 HydrophobicContact CG-CE1 4.38Å; R272-F311 VanDerWaalsContact NH1-CE2 3.26Å; N308-F311 HydrophobicContact CB-CD2 4.4Å; N308-F311 PolarHBondContact O-N 2.63Å; Y309-F311 PolarHBondContact O-N 2.73Å; F311-T313 PolarHBondContact O-N 3.22Å; F311-L327 HydrophobicContact CB-CD1 3.94Å; F311-L327 HydrophobicContact CD1-CD1 4.05Å; F311-L327 HydrophobicContact CG-CD1 4.19Å
312C95.3Very high94.8Very high27 Ų2769.4 Ų69.418%0.18236%0.364CS..  trans-84.9108.5175.3-173.70000110.6P302 Y309 S318 C321P302-C312 HydrophobicContact CG-CB 4.29Å; Y309-C312 WeakPolarHBondContact O-CB 3.24Å; Y309-C312 PolarHBondContact O-N 3.29Å; Y309-C312 VanDerWaalsContact O-N 3.11Å; C312-S318 PolarHBondContact SG-OG 3.1Å; C312-C321 HydrophobicContact CB-CB 3.8Å; C312-C321 WeakPolarHBondContact CB-SG 3.17Å; C312-C321 VanDerWaalsContact SG-CA 3.57Å; C312-C321 WeakPolarHBondContact SG-CB 3.43Å; C312-C321 CovalentContact SG-SG 2.03Å; C312-C321 PolarHBondContact SG-SG 3.26Å
313T92.6Very high94.8Very high71 Ų7169.4 Ų69.444%0.43636%0.362SS..  trans-95.1-26.4-174.153.50000114.1W238 F311 D328W238-T313 HydrophobicContact CE3-CG2 4.41Å; W238-T313 HydrophobicContact CZ3-CG2 3.84Å; F311-T313 PolarHBondContact O-N 3.22Å; T313-D328 HydrophobicContact CG2-CB 4.47Å; T313-D328 WeakPolarHBondContact OG1-CB 3.38Å; T313-D328 PolarHBondContact OG1-OD2 3.16Å
314D92.4Very high94.8Very high52 Ų5266 Ų6628%0.27833%0.334SS..  trans-140.9113.2-173.9-174.6-44000110.6V316 I317 S318D314-V316 VanDerWaalsContact C-N 3.3Å; D314-V316 PolarHBondContact O-N 3.39Å; D314-V316 WeakPolarHBondContact OD1-CA 3.25Å; D314-V316 WeakPolarHBondContact OD1-CB 3.48Å; D314-V316 PolarHBondContact OD1-N 3.33Å; D314-I317 HydrophobicContact CB-CB 4.28Å; D314-I317 HydrophobicContact CB-CG1 4.36Å; D314-I317 PolarHBondContact OD1-N 2.66Å; D314-S318 WeakPolarHBondContact O-CB 3.39Å; D314-S318 PolarHBondContact O-N 2.87Å; D314-S318 PolarHBondContact O-OG 3.39Å
315Y93Very high94.8Very high148 Ų14861.1 Ų61.158%0.5831%0.311SS*.THydrogen-bonded Turntrans-70.8-21-178.3-77.6-100.4000113.8Q319 N320 C321Y315-Q319 PolarHBondContact O-N 2.96Å; Y315-N320 WeakPolarHBondContact CD1-OD1 3.22Å; Y315-N320 PolarHBondContact O-N 3.09Å; Y315-C321 VanDerWaalsContact CE1-SG 3.57Å
316V92.3Very high94.8Very high124 Ų12461 Ų6175%0.75231%0.311SS*.THydrogen-bonded Turntrans-81.6-50.3179.3179.80000109.5D314 Q319D314-V316 VanDerWaalsContact C-N 3.3Å; D314-V316 PolarHBondContact O-N 3.39Å; D314-V316 WeakPolarHBondContact OD1-CA 3.25Å; D314-V316 WeakPolarHBondContact OD1-CB 3.48Å; D314-V316 PolarHBondContact OD1-N 3.33Å; V316-Q319 PolarHBondContact O-N 3.09Å
317I92.4Very high94.9Very high28 Ų2853.2 Ų53.214%0.14428%0.277CS..THydrogen-bonded Turntrans-66.9-40.8-179.7-59.2-59.8000110.9D314 Q319 L323 F339 L391 P407D314-I317 HydrophobicContact CB-CB 4.28Å; D314-I317 HydrophobicContact CB-CG1 4.36Å; D314-I317 PolarHBondContact OD1-N 2.66Å; I317-Q319 PolarHBondContact O-N 2.86Å; I317-L323 VanDerWaalsContact O-CD1 3.22Å; I317-L323 WeakPolarHBondContact O-CD1 3.46Å; I317-F339 HydrophobicContact CG2-CZ 4.3Å; I317-L391 HydrophobicContact CD1-CD1 4.4Å; I317-L391 HydrophobicContact CD1-CD2 4.07Å; I317-L391 HydrophobicContact CG1-CD2 4Å; I317-L391 HydrophobicContact CG2-CD1 4.14Å; I317-L391 HydrophobicContact CG2-CD2 4.01Å; I317-P407 HydrophobicContact CD1-CB 3.7Å; I317-P407 HydrophobicContact CD1-CG 3.98Å
318S92Very high94.9Very high19 Ų1948.9 Ų48.913%0.13325%0.254CS..THydrogen-bonded Turntrans-80.53.5-179.868.30000114.8C312 D314 C321 T322 L323C312-S318 PolarHBondContact SG-OG 3.1Å; D314-S318 WeakPolarHBondContact O-CB 3.39Å; D314-S318 PolarHBondContact O-N 2.87Å; D314-S318 PolarHBondContact O-OG 3.39Å; S318-C321 PolarHBondContact O-N 3.45Å; S318-C321 WeakPolarHBondContact OG-CA 3.29Å; S318-C321 PolarHBondContact OG-N 3.3Å; S318-T322 PolarHBondContact O-N 3.37Å; S318-L323 PolarHBondContact O-N 3.02Å; S318-L323 VanDerWaalsContact O-N 3.1Å
319Q92.9Very high95Very high110 Ų11048.3 Ų48.351%0.51425%0.251SS..THydrogen-bonded Turntrans52.260.5-176.1-57.3-179.122.400112.1Y315 V316 I317 C321 T322 L323Y315-Q319 PolarHBondContact O-N 2.96Å; V316-Q319 PolarHBondContact O-N 3.09Å; I317-Q319 PolarHBondContact O-N 2.86Å; Q319-C321 VanDerWaalsContact C-N 3.34Å; Q319-C321 PolarHBondContact O-N 2.94Å; Q319-T322 WeakPolarHBondContact O-CB 3.5Å; Q319-T322 WeakPolarHBondContact O-CG2 3.19Å; Q319-T322 PolarHBondContact O-N 3.18Å; Q319-T322 PolarHBondContact O-OG1 2.94Å; Q319-L323 HydrophobicContact CB-CG 4.33Å; Q319-L323 HydrophobicContact CG-CD1 4.27Å; Q319-L323 HydrophobicContact CG-CD2 4.44Å; Q319-L323 HydrophobicContact CG-CG 4.19Å
320N94.6Very high95Very high118 Ų11844 Ų4463%0.63124%0.237SC*.THydrogen-bonded Turntrans58.742.8-174.7-162.542.1000112.8Y315 T322Y315-N320 WeakPolarHBondContact CD1-OD1 3.22Å; Y315-N320 PolarHBondContact O-N 3.09Å; N320-T322 VanDerWaalsContact C-N 3.33Å; N320-T322 PolarHBondContact O-N 3.11Å
321C94.7Very high94.9Very high11 Ų1146 Ų467%0.07426%0.255CS..THydrogen-bonded Turntrans57.140.1-178.7-53.40000114P302 C312 Y315 S318 Q319P302-C321 HydrophobicContact CB-CB 4.4Å; P302-C321 WeakPolarHBondContact CD-O 3.48Å; P302-C321 HydrophobicContact CG-CB 3.98Å; C312-C321 HydrophobicContact CB-CB 3.8Å; C312-C321 WeakPolarHBondContact CB-SG 3.17Å; C312-C321 VanDerWaalsContact SG-CA 3.57Å; C312-C321 WeakPolarHBondContact SG-CB 3.43Å; C312-C321 CovalentContact SG-SG 2.03Å; C312-C321 PolarHBondContact SG-SG 3.26Å; Y315-C321 VanDerWaalsContact CE1-SG 3.57Å; S318-C321 PolarHBondContact O-N 3.45Å; S318-C321 WeakPolarHBondContact OG-CA 3.29Å; S318-C321 PolarHBondContact OG-N 3.3Å; Q319-C321 VanDerWaalsContact C-N 3.34Å; Q319-C321 PolarHBondContact O-N 2.94Å
322T95.4Very high94.9Very high62 Ų6246 Ų4638%0.3826%0.258SS..THydrogen-bonded Turntrans-105.8-20177.561.40000113.2S301 A303 S318 Q319 N320S301-T322 WeakPolarHBondContact CB-O 3.45Å; S301-T322 PolarHBondContact OG-O 3.13Å; S301-T322 VanDerWaalsContact OG-O 3.11Å; A303-T322 HydrophobicContact CB-CG2 4.44Å; S318-T322 PolarHBondContact O-N 3.37Å; Q319-T322 WeakPolarHBondContact O-CB 3.5Å; Q319-T322 WeakPolarHBondContact O-CG2 3.19Å; Q319-T322 PolarHBondContact O-N 3.18Å; Q319-T322 PolarHBondContact O-OG1 2.94Å; N320-T322 VanDerWaalsContact C-N 3.33Å; N320-T322 PolarHBondContact O-N 3.11Å
323L94.9Very high95Very high29 Ų2948 Ų4815%0.15226%0.263CS..  trans-69.3136.9175.2-65.1-173.1000112.3S301 I317 S318 Q319 S351S301-L323 VanDerWaalsContact CB-O 3.3Å; S301-L323 WeakPolarHBondContact CB-O 3.27Å; I317-L323 VanDerWaalsContact O-CD1 3.22Å; I317-L323 WeakPolarHBondContact O-CD1 3.46Å; S318-L323 PolarHBondContact O-N 3.02Å; S318-L323 VanDerWaalsContact O-N 3.1Å; Q319-L323 HydrophobicContact CB-CG 4.33Å; Q319-L323 HydrophobicContact CG-CD1 4.27Å; Q319-L323 HydrophobicContact CG-CD2 4.44Å; Q319-L323 HydrophobicContact CG-CG 4.19Å; L323-S351 WeakPolarHBondContact CD2-OG 3.27Å
324A96.2Very high95Very high3 Ų348 Ų483%0.02527%0.271CS..  trans-120163.1-178.900000111.8A348 S349A324-A348 VanDerWaalsContact O-CA 3.27Å; A324-A348 WeakPolarHBondContact O-CA 3.47Å; A324-A348 WeakPolarHBondContact O-CB 3.49Å; A324-S349 PolarHBondContact N-OG 2.86Å; A324-S349 PolarHBondContact O-N 3.09Å; A324-S349 VanDerWaalsContact O-N 3.11Å
325G96.3Very high95.1Very high1 Ų147.3 Ų47.31%0.0128%0.275CS..SBendtrans81.45.6172.900000116F299 S341F299-G325 PolarHBondContact O-N 3.33Å; G325-S341 WeakPolarHBondContact O-CB 3.25Å
326V97.1Very high95.3Very high31 Ų3145.5 Ų45.519%0.18827%0.268CS..EExtended strand (participates in β ladder)trans-134.4146177.1-63.90000110.8F339 I340 F345 I352 I409V326-F339 HydrophobicContact CB-CD1 4.23Å; V326-F339 HydrophobicContact CG2-CD1 4.34Å; V326-I340 CarbonylContact C-O 3.57Å; V326-I340 WeakPolarHBondContact CA-O 3.29Å; V326-F345 HydrophobicContact CG1-CD1 4.15Å; V326-F345 HydrophobicContact CG1-CE1 4.18Å; V326-I352 HydrophobicContact CB-CD1 4.46Å; V326-I352 HydrophobicContact CG1-CD1 3.76Å; V326-I352 HydrophobicContact CG2-CD1 3.81Å; V326-I409 HydrophobicContact CB-CD1 4.1Å; V326-I409 HydrophobicContact CG1-CD1 3.92Å; V326-I409 HydrophobicContact CG2-CD1 3.83Å
327L97.7Very high95.5Very high9 Ų940 Ų405%0.04724%0.235CC..EExtended strand (participates in β ladder)trans-128117.8-179.4-178.170.8000110W238 R272 F311 I329 F339 I340W238-L327 HydrophobicContact CH2-CD1 3.57Å; W238-L327 HydrophobicContact CH2-CD2 4.47Å; W238-L327 HydrophobicContact CH2-CG 3.99Å; W238-L327 HydrophobicContact CZ2-CD1 4.15Å; W238-L327 HydrophobicContact CZ2-CD2 4.39Å; W238-L327 HydrophobicContact CZ2-CG 4.39Å; W238-L327 HydrophobicContact CZ3-CD1 4.25Å; R272-L327 HydrophobicContact CG-CD2 4.01Å; F311-L327 HydrophobicContact CB-CD1 3.94Å; F311-L327 HydrophobicContact CD1-CD1 4.05Å; F311-L327 HydrophobicContact CG-CD1 4.19Å; L327-I329 HydrophobicContact CD2-CG2 3.77Å; L327-I329 HydrophobicContact CG-CG2 3.87Å; L327-I329 PolarHBondContact O-N 2.99Å; L327-F339 CarbonylContact O-C 3.51Å; L327-F339 VanDerWaalsContact O-CA 3.27Å; L327-F339 WeakPolarHBondContact O-CA 3.46Å; L327-I340 PolarHBondContact N-O 2.97Å; L327-I340 PolarHBondContact O-N 2.99Å
328D97.7Very high95.8Very high21 Ų2139.6 Ų39.611%0.11223%0.233CC..EExtended strand (participates in β ladder)trans-73.4111.3172.7177.95.7000110.3W238 T313 S330 F339W238-D328 WeakPolarHBondContact CH2-O 3.36Å; T313-D328 HydrophobicContact CG2-CB 4.47Å; T313-D328 WeakPolarHBondContact OG1-CB 3.38Å; T313-D328 PolarHBondContact OG1-OD2 3.16Å; D328-S330 WeakPolarHBondContact OD1-CB 3.46Å; D328-S330 PolarHBondContact OD1-N 3.04Å; D328-S330 PolarHBondContact OD1-OG 2.77Å; D328-S330 PolarHBondContact OD2-OG 3.39Å; D328-F339 HydrophobicContact CB-CD1 4.13Å; D328-F339 HydrophobicContact CB-CE1 3.6Å; D328-F339 HydrophobicContact CB-CE2 4.19Å; D328-F339 HydrophobicContact CB-CZ 3.62Å
329I97.7Very high96.1Very high2 Ų239.4 Ų39.41%0.0123%0.23CC..  trans-107.122.2179.164.3159.5000112.5I270 L327 A331 C332 K333 V338 I340I270-I329 WeakPolarHBondContact O-CG2 3.22Å; L327-I329 HydrophobicContact CD2-CG2 3.77Å; L327-I329 HydrophobicContact CG-CG2 3.87Å; L327-I329 PolarHBondContact O-N 2.99Å; I329-A331 PolarHBondContact O-N 2.83Å; I329-C332 PolarHBondContact O-N 3.05Å; I329-C332 VanDerWaalsContact O-N 3.15Å; I329-C332 PolarHBondContact O-SG 3.39Å; I329-K333 HydrophobicContact CD1-CD 4.4Å; I329-K333 HydrophobicContact CD1-CG 3.92Å; I329-K333 HydrophobicContact CG1-CG 4.12Å; I329-K333 WeakPolarHBondContact O-CG 3.47Å; I329-K333 PolarHBondContact O-N 3.2Å; I329-V338 HydrophobicContact CD1-CB 4.5Å; I329-V338 HydrophobicContact CD1-CG1 3.89Å; I329-V338 HydrophobicContact CG1-CB 4.02Å; I329-V338 HydrophobicContact CG1-CG1 3.83Å; I329-V338 WeakPolarHBondContact CG1-O 3.1Å; I329-V338 PolarHBondContact N-O 2.81Å; I329-I340 HydrophobicContact CD1-CD1 3.83Å; I329-I340 HydrophobicContact CD1-CG1 3.48Å; I329-I340 VanDerWaalsContact CD1-CG1 3.48Å; I329-I340 HydrophobicContact CG1-CG1 3.93Å; I329-I340 HydrophobicContact CG2-CG1 4.11Å
330S96.8Very high96.3Very high25 Ų2534.6 Ų34.618%0.17521%0.208CC..G310 helixtrans-55.9-35.5-178.8590000113.2D328 C332 K333 A334 G335 R336D328-S330 WeakPolarHBondContact OD1-CB 3.46Å; D328-S330 PolarHBondContact OD1-N 3.04Å; D328-S330 PolarHBondContact OD1-OG 2.77Å; D328-S330 PolarHBondContact OD2-OG 3.39Å; S330-C332 VanDerWaalsContact C-N 3.3Å; S330-C332 PolarHBondContact O-N 3.35Å; S330-K333 CarbonylContact O-C 3.48Å; S330-K333 PolarHBondContact O-N 3.05Å; S330-A334 PolarHBondContact O-N 3.11Å; S330-G335 WeakPolarHBondContact O-CA 3.23Å; S330-G335 PolarHBondContact O-N 2.8Å; S330-R336 WeakPolarHBondContact CA-O 3.46Å; S330-R336 WeakPolarHBondContact CB-O 3.4Å
331A95.4Very high96.5Very high51 Ų5129 Ų2942%0.42118%0.178SC..G310 helixtrans-55.3-40.7177.500000113Y237 I329Y237-A331 HydrophobicContact CD1-CB 4.17Å; Y237-A331 HydrophobicContact CG-CB 4.38Å; I329-A331 PolarHBondContact O-N 2.83Å
332C95.8Very high96.7Very high25 Ų2528.6 Ų28.617%0.16918%0.175CC..G310 helixtrans-93.4-1.617874.30000113.8Y237 C271 I329 S330Y237-C332 HydrophobicContact CD1-CB 4.21Å; Y237-C332 HydrophobicContact CD2-CB 3.79Å; Y237-C332 HydrophobicContact CE1-CB 3.88Å; Y237-C332 HydrophobicContact CE2-CB 3.45Å; Y237-C332 VanDerWaalsContact CE2-CB 3.45Å; Y237-C332 HydrophobicContact CG-CB 4.18Å; C271-C332 HydrophobicContact CB-CB 3.56Å; C271-C332 WeakPolarHBondContact CB-SG 3.39Å; C271-C332 WeakPolarHBondContact SG-CB 3.28Å; C271-C332 CovalentContact SG-SG 2Å; C271-C332 PolarHBondContact SG-SG 2.89Å; I329-C332 PolarHBondContact O-N 3.05Å; I329-C332 VanDerWaalsContact O-N 3.15Å; I329-C332 PolarHBondContact O-SG 3.39Å; S330-C332 VanDerWaalsContact C-N 3.3Å; S330-C332 PolarHBondContact O-N 3.35Å
333K96.3Very high96.8Very high67 Ų6725.7 Ų25.729%0.29116%0.157SC..G310 helixtrans-112.231.5176.6-59-59.9177.2-177.90111.9I329 S330 G335 R336 V338I329-K333 HydrophobicContact CD1-CD 4.4Å; I329-K333 HydrophobicContact CD1-CG 3.92Å; I329-K333 HydrophobicContact CG1-CG 4.12Å; I329-K333 WeakPolarHBondContact O-CG 3.47Å; I329-K333 PolarHBondContact O-N 3.2Å; S330-K333 CarbonylContact O-C 3.48Å; S330-K333 PolarHBondContact O-N 3.05Å; K333-G335 VanDerWaalsContact C-N 3.27Å; K333-G335 PolarHBondContact O-N 3.34Å; K333-R336 HydrophobicContact CB-CB 4.42Å; K333-R336 WeakPolarHBondContact O-CB 3.26Å; K333-R336 PolarHBondContact O-N 2.91Å; K333-R336 VanDerWaalsContact O-N 3.13Å; K333-R336 PolarHBondContact O-NE 3.36Å; K333-R336 PolarHBondContact O-NH1 2.89Å; K333-R336 PolarHBondContact O-NH2 3.25Å; K333-V338 HydrophobicContact CB-CB 4.48Å; K333-V338 HydrophobicContact CB-CG2 4.17Å; K333-V338 HydrophobicContact CG-CB 4.18Å; K333-V338 HydrophobicContact CG-CG2 4.2Å
334A93.4Very high97Very high73 Ų7324.7 Ų24.760%0.60315%0.152SC*.THydrogen-bonded Turntrans51.844.2178.100000112.8S330 R336S330-A334 PolarHBondContact O-N 3.11Å; A334-R336 VanDerWaalsContact C-N 3.25Å; A334-R336 PolarHBondContact O-N 3.13Å
335G94.8Very high97.1Very high36 Ų3624.6 Ų24.637%0.37115%0.151SC..THydrogen-bonded Turntrans78.8-5.5177.900000115.3L147 S330 K333L147-G335 VanDerWaalsContact CD2-O 3.29Å; L147-G335 WeakPolarHBondContact CD2-O 3.07Å; S330-G335 WeakPolarHBondContact O-CA 3.23Å; S330-G335 PolarHBondContact O-N 2.8Å; K333-G335 VanDerWaalsContact C-N 3.27Å; K333-G335 PolarHBondContact O-N 3.34Å
336R96.3Very high97.2Very high111 Ų11125 Ų2542%0.41915%0.153SC..  trans-62.5138.9177.1-69.5-178.3-68.2-80.62.5109.5A143 L147 S330 K333 A334 V338A143-R336 HydrophobicContact CB-CG 4.42Å; L147-R336 HydrophobicContact CD1-CG 4.11Å; S330-R336 WeakPolarHBondContact CA-O 3.46Å; S330-R336 WeakPolarHBondContact CB-O 3.4Å; K333-R336 HydrophobicContact CB-CB 4.42Å; K333-R336 WeakPolarHBondContact O-CB 3.26Å; K333-R336 PolarHBondContact O-N 2.91Å; K333-R336 VanDerWaalsContact O-N 3.13Å; K333-R336 PolarHBondContact O-NE 3.36Å; K333-R336 PolarHBondContact O-NH1 2.89Å; K333-R336 PolarHBondContact O-NH2 3.25Å; A334-R336 VanDerWaalsContact C-N 3.25Å; A334-R336 PolarHBondContact O-N 3.13Å; R336-V338 HydrophobicContact CB-CG2 4.1Å; R336-V338 PolarHBondContact O-N 3.45Å
337P96.9Very high97.1Very high9 Ų925.7 Ų25.76%0.05815%0.154CC..  trans-79.357.4-16935.4-39.8000112.5A146 L390 L391A146-P337 HydrophobicContact CB-CB 4.18Å; A146-P337 HydrophobicContact CB-CG 3.77Å; P337-L390 HydrophobicContact CG-CD1 4.07Å; P337-L390 HydrophobicContact CG-CG 4.25Å; P337-L390 WeakPolarHBondContact O-CD1 3.29Å; P337-L391 HydrophobicContact CB-CB 4.17Å; P337-L391 PolarHBondContact O-N 3.37Å
338V98.4Very high97.1Very high19 Ų1926 Ų2612%0.11516%0.158CC..EExtended strand (participates in β ladder)trans-89128.3-175.4-178.30000110.1I329 K333 R336 V388 N389 L390I329-V338 HydrophobicContact CD1-CB 4.5Å; I329-V338 HydrophobicContact CD1-CG1 3.89Å; I329-V338 HydrophobicContact CG1-CB 4.02Å; I329-V338 HydrophobicContact CG1-CG1 3.83Å; I329-V338 WeakPolarHBondContact CG1-O 3.1Å; I329-V338 PolarHBondContact N-O 2.81Å; K333-V338 HydrophobicContact CB-CB 4.48Å; K333-V338 HydrophobicContact CB-CG2 4.17Å; K333-V338 HydrophobicContact CG-CB 4.18Å; K333-V338 HydrophobicContact CG-CG2 4.2Å; R336-V338 HydrophobicContact CB-CG2 4.1Å; R336-V338 PolarHBondContact O-N 3.45Å; V338-V388 HydrophobicContact CG1-CG1 4.11Å; V338-N389 WeakPolarHBondContact CA-O 3.47Å; V338-L390 HydrophobicContact CG2-CD1 4Å
339F98.3Very high97Very high15 Ų1526.4 Ų26.47%0.06616%0.162CC..EExtended strand (participates in β ladder)trans-117.4135.3176.6-78.5-108.5000110.3I317 V326 L327 D328 N389 L391 I409I317-F339 HydrophobicContact CG2-CZ 4.3Å; V326-F339 HydrophobicContact CB-CD1 4.23Å; V326-F339 HydrophobicContact CG2-CD1 4.34Å; L327-F339 CarbonylContact O-C 3.51Å; L327-F339 VanDerWaalsContact O-CA 3.27Å; L327-F339 WeakPolarHBondContact O-CA 3.46Å; D328-F339 HydrophobicContact CB-CD1 4.13Å; D328-F339 HydrophobicContact CB-CE1 3.6Å; D328-F339 HydrophobicContact CB-CE2 4.19Å; D328-F339 HydrophobicContact CB-CZ 3.62Å; F339-N389 HydrophobicContact CB-CB 4.13Å; F339-N389 PolarHBondContact N-O 2.91Å; F339-N389 WeakPolarHBondContact O-CA 3.32Å; F339-N389 WeakPolarHBondContact O-CB 3.39Å; F339-N389 PolarHBondContact O-N 2.91Å; F339-N389 PolarHBondContact O-ND2 2.93Å; F339-L391 HydrophobicContact CD2-CB 3.76Å; F339-L391 HydrophobicContact CE2-CB 3.51Å; F339-L391 HydrophobicContact CE2-CD2 3.71Å; F339-L391 HydrophobicContact CE2-CG 4.21Å; F339-L391 HydrophobicContact CZ-CB 4.42Å; F339-L391 HydrophobicContact CZ-CD2 4.01Å; F339-I409 HydrophobicContact CB-CG2 4.24Å; F339-I409 HydrophobicContact CD1-CD1 3.92Å; F339-I409 HydrophobicContact CE1-CD1 4.29Å; F339-I409 HydrophobicContact CG-CD1 4.33Å
340I98.3Very high96.8Very high8 Ų830.1 Ų30.14%0.04119%0.188CC..EExtended strand (participates in β ladder)trans-101.5141.3172.3-59.8-59.2000109.8I270 V326 L327 I329 L386 Q387 V388I270-I340 HydrophobicContact CG2-CG1 4.39Å; I270-I340 HydrophobicContact CG2-CG2 3.85Å; V326-I340 CarbonylContact C-O 3.57Å; V326-I340 WeakPolarHBondContact CA-O 3.29Å; L327-I340 PolarHBondContact N-O 2.97Å; L327-I340 PolarHBondContact O-N 2.99Å; I329-I340 HydrophobicContact CD1-CD1 3.83Å; I329-I340 HydrophobicContact CD1-CG1 3.48Å; I329-I340 VanDerWaalsContact CD1-CG1 3.48Å; I329-I340 HydrophobicContact CG1-CG1 3.93Å; I329-I340 HydrophobicContact CG2-CG1 4.11Å; I340-L386 HydrophobicContact CG2-CD2 4.17Å; I340-Q387 WeakPolarHBondContact CA-O 3.48Å; I340-V388 HydrophobicContact CD1-CG2 4.12Å
341S98.3Very high96.5Very high0 Ų030.8 Ų30.80%019%0.193CC..EExtended strand (participates in β ladder)trans-141.5179.5170.464.40000110.3G325 F345 Q387 N389G325-S341 WeakPolarHBondContact O-CB 3.25Å; S341-F345 VanDerWaalsContact OG-CD1 3.29Å; S341-F345 WeakPolarHBondContact OG-CD1 3.49Å; S341-F345 WeakPolarHBondContact OG-CE1 3.36Å; S341-Q387 PolarHBondContact N-O 3.23Å; S341-Q387 PolarHBondContact O-N 3.37Å; S341-Q387 WeakPolarHBondContact OG-CB 3.4Å; S341-Q387 PolarHBondContact OG-NE2 2.94Å; S341-N389 PolarHBondContact OG-ND2 3.4Å
342L98.3Very high96.5Very high4 Ų428.8 Ų28.82%0.02118%0.175CC..SBendtrans-75.5157.8159.9-63.6178.7000110.1F299 F345 L346F299-L342 HydrophobicContact CD2-CD1 4.25Å; F299-L342 HydrophobicContact CD2-CG 4.38Å; F299-L342 HydrophobicContact CE2-CD1 4.06Å; F299-L342 HydrophobicContact CE2-CD2 3.95Å; F299-L342 HydrophobicContact CE2-CG 3.98Å; F299-L342 HydrophobicContact CZ-CD2 4.04Å; F299-L342 HydrophobicContact CZ-CG 4.31Å; L342-F345 WeakPolarHBondContact O-CA 3.47Å; L342-F345 PolarHBondContact O-N 2.93Å; L342-F345 VanDerWaalsContact O-N 3.11Å; L342-L346 HydrophobicContact CB-CB 3.83Å; L342-L346 HydrophobicContact CD1-CB 4.34Å; L342-L346 HydrophobicContact CD1-CD2 4.08Å; L342-L346 HydrophobicContact CD1-CG 4.27Å
343P98.7Very high96.3Very high0 Ų029.7 Ų29.70%018%0.178CC..G310 helixtrans-54.4141.9177.8-2129000113.3F345 L346 H366 R385 W414P343-F345 PolarHBondContact O-N 2.84Å; P343-F345 VanDerWaalsContact O-N 3.1Å; P343-L346 WeakPolarHBondContact O-CB 3.27Å; P343-L346 PolarHBondContact O-N 2.82Å; P343-H366 HydrophobicContact CB-CB 3.79Å; P343-H366 WeakPolarHBondContact CD-O 3.41Å; P343-H366 HydrophobicContact CG-CB 3.99Å; P343-H366 PolarHBondContact O-ND1 2.76Å; P343-R385 HydrophobicContact CG-CB 3.86Å; P343-W414 HydrophobicContact CB-CB 3.89Å; P343-W414 HydrophobicContact CB-CD2 3.76Å; P343-W414 HydrophobicContact CB-CE3 3.91Å; P343-W414 HydrophobicContact CB-CG 3.77Å; P343-W414 HydrophobicContact CG-CB 4.12Å; P343-W414 HydrophobicContact CG-CD2 4.05Å; P343-W414 HydrophobicContact CG-CE3 3.7Å; P343-W414 HydrophobicContact CG-CG 4.26Å; P343-W414 HydrophobicContact CG-CZ3 4.38Å
344H98.4Very high96.2Very high9 Ų932.4 Ų32.44%0.04219%0.191CC..G310 helixtrans52.727-174.1-67-101.3000114.1F68 Q87 L346 L359 S360 P361 H366 W414F68-H344 AromaticContact CE1-CE1 3.71Å; F68-H344 AromaticContact CE1-NE2 3.97Å; F68-H344 AromaticContact CZ-NE2 3.96Å; Q87-H344 PolarHBondContact OE1-NE2 2.83Å; H344-L346 VanDerWaalsContact C-N 3.26Å; H344-L346 PolarHBondContact O-N 3.12Å; H344-L359 HydrophobicContact CB-CB 4.38Å; H344-L359 WeakPolarHBondContact ND1-CA 3.47Å; H344-S360 PolarHBondContact ND1-N 3.24Å; H344-P361 HydrophobicContact CB-CB 4.24Å; H344-H366 AromaticContact CD2-CE1 3.15Å; H344-H366 PolarHBondContact CD2-CE1 3.06Å; H344-H366 AromaticContact CD2-ND1 3.91Å; H344-H366 AromaticContact CD2-NE2 3.37Å; H344-H366 PolarHBondContact CD2-NE2 3.07Å; H344-H366 AromaticContact CG-CE1 3.55Å; H344-W414 AromaticContact CD2-NE1 3.94Å; H344-W414 AromaticContact NE2-NE1 3.56Å
345F98.3Very high96.1Very high1 Ų130 Ų300%0.00417%0.168CC..G310 helixtrans55.937.8-174-61-58.1000113.4V326 S341 L342 P343 H347 A348 I352 L353 V356 L359 Q387 N389 I409 P411V326-F345 HydrophobicContact CG1-CD1 4.15Å; V326-F345 HydrophobicContact CG1-CE1 4.18Å; S341-F345 VanDerWaalsContact OG-CD1 3.29Å; S341-F345 WeakPolarHBondContact OG-CD1 3.49Å; S341-F345 WeakPolarHBondContact OG-CE1 3.36Å; L342-F345 WeakPolarHBondContact O-CA 3.47Å; L342-F345 PolarHBondContact O-N 2.93Å; L342-F345 VanDerWaalsContact O-N 3.11Å; P343-F345 PolarHBondContact O-N 2.84Å; P343-F345 VanDerWaalsContact O-N 3.1Å; F345-H347 PolarHBondContact O-N 3.29Å; F345-A348 HydrophobicContact CB-CB 3.71Å; F345-A348 VanDerWaalsContact O-CB 3.25Å; F345-A348 WeakPolarHBondContact O-CB 3.28Å; F345-A348 PolarHBondContact O-N 2.93Å; F345-I352 HydrophobicContact CD1-CG2 3.93Å; F345-I352 HydrophobicContact CD2-CG2 3.84Å; F345-I352 HydrophobicContact CE1-CG2 3.96Å; F345-I352 HydrophobicContact CE2-CG2 3.89Å; F345-I352 HydrophobicContact CG-CG2 3.89Å; F345-I352 HydrophobicContact CZ-CG2 3.96Å; F345-L353 HydrophobicContact CB-CD1 4.37Å; F345-L353 HydrophobicContact CB-CG 4.29Å; F345-V356 HydrophobicContact CE2-CG2 4.45Å; F345-L359 HydrophobicContact CD2-CD1 3.27Å; F345-L359 HydrophobicContact CE2-CD1 3.59Å; F345-L359 HydrophobicContact CG-CD1 4.39Å; F345-Q387 VanDerWaalsContact CE1-NE2 3.34Å; F345-N389 WeakPolarHBondContact CE1-OD1 3.19Å; F345-N389 VanDerWaalsContact CZ-OD1 3.28Å; F345-N389 WeakPolarHBondContact CZ-OD1 3.49Å; F345-I409 HydrophobicContact CE1-CG2 3.97Å; F345-I409 HydrophobicContact CZ-CB 4.43Å; F345-I409 HydrophobicContact CZ-CG2 3.87Å; F345-P411 HydrophobicContact CE2-CB 4.24Å; F345-P411 HydrophobicContact CE2-CG 4.19Å; F345-P411 HydrophobicContact CZ-CB 4.06Å; F345-P411 HydrophobicContact CZ-CG 4.39Å
346L97.9Very high96.1Very high10 Ų1028.6 Ų28.65%0.05215%0.153CC..THydrogen-bonded Turntrans-51.1130.3171.9178.368.7000110.2L342 P343 H344 A348 P361 E363 H366L342-L346 HydrophobicContact CB-CB 3.83Å; L342-L346 HydrophobicContact CD1-CB 4.34Å; L342-L346 HydrophobicContact CD1-CD2 4.08Å; L342-L346 HydrophobicContact CD1-CG 4.27Å; P343-L346 WeakPolarHBondContact O-CB 3.27Å; P343-L346 PolarHBondContact O-N 2.82Å; H344-L346 VanDerWaalsContact C-N 3.26Å; H344-L346 PolarHBondContact O-N 3.12Å; L346-A348 PolarHBondContact O-N 3.22Å; L346-P361 HydrophobicContact CB-CB 4.21Å; L346-P361 HydrophobicContact CD1-CB 4.1Å; L346-E363 HydrophobicContact CD1-CG 3.9Å; L346-E363 HydrophobicContact CD2-CG 4.43Å; L346-H366 HydrophobicContact CB-CB 4.15Å; L346-H366 HydrophobicContact CD2-CB 3.85Å
347H95.9Very high96.2Very high45 Ų4527.8 Ų27.821%0.20815%0.153CC..THydrogen-bonded Turntrans65.38.8-175.2-52.2-42000117.1R296 F345 E363R296-H347 HydrophobicContact CB-CB 4.34Å; R296-H347 HydrophobicContact CG-CB 3.96Å; F345-H347 PolarHBondContact O-N 3.29Å; H347-E363 IonicContact CE1-OE1 3.89Å; H347-E363 PolarHBondContact CE1-OE1 3.28Å
348A96.8Very high96.1Very high16 Ų1630 Ų3013%0.13218%0.178CC..  trans-78.9159.8174.900000113.7A324 F345 L346 I352 L353A324-A348 VanDerWaalsContact O-CA 3.27Å; A324-A348 WeakPolarHBondContact O-CA 3.47Å; A324-A348 WeakPolarHBondContact O-CB 3.49Å; F345-A348 HydrophobicContact CB-CB 3.71Å; F345-A348 VanDerWaalsContact O-CB 3.25Å; F345-A348 WeakPolarHBondContact O-CB 3.28Å; F345-A348 PolarHBondContact O-N 2.93Å; L346-A348 PolarHBondContact O-N 3.22Å; A348-I352 HydrophobicContact CB-CD1 4.2Å; A348-L353 HydrophobicContact CB-CD1 4.5Å
349S95.9Very high96.1Very high28 Ų2830.4 Ų30.420%0.19618%0.18CC..  trans-59.1138172.9-60.90000111A324 S351 I352A324-S349 PolarHBondContact N-OG 2.86Å; A324-S349 PolarHBondContact O-N 3.09Å; A324-S349 VanDerWaalsContact O-N 3.11Å; S349-S351 PolarHBondContact O-N 2.86Å; S349-S351 VanDerWaalsContact O-N 3.09Å; S349-I352 WeakPolarHBondContact O-CB 3.47Å; S349-I352 PolarHBondContact O-N 2.88Å
350S92.9Very high96Very high81 Ų8133.7 Ų33.757%0.56620%0.204SC*.Hα-helixtrans-55-33-176.653.30000113.9I352 L353 H354S350-I352 PolarHBondContact O-N 2.91Å; S350-L353 PolarHBondContact O-N 3.35Å; S350-H354 PolarHBondContact O-CD2 3.25Å; S350-H354 PolarHBondContact O-N 2.91Å
351S91.8Very high96Very high39 Ų3936 Ų3627%0.27322%0.219SC..Hα-helixtrans-57.3-3017658.40000113.6L323 S349L323-S351 WeakPolarHBondContact CD2-OG 3.27Å; S349-S351 PolarHBondContact O-N 2.86Å; S349-S351 VanDerWaalsContact O-N 3.09Å
352I93.8Very high95.9Very high9 Ų939.3 Ų39.35%0.04624%0.238CC..Hα-helixtrans-72.5-37.4178.3-62174.3000110.4V326 F345 A348 S349 S350 H354 I409V326-I352 HydrophobicContact CB-CD1 4.46Å; V326-I352 HydrophobicContact CG1-CD1 3.76Å; V326-I352 HydrophobicContact CG2-CD1 3.81Å; F345-I352 HydrophobicContact CD1-CG2 3.93Å; F345-I352 HydrophobicContact CD2-CG2 3.84Å; F345-I352 HydrophobicContact CE1-CG2 3.96Å; F345-I352 HydrophobicContact CE2-CG2 3.89Å; F345-I352 HydrophobicContact CG-CG2 3.89Å; F345-I352 HydrophobicContact CZ-CG2 3.96Å; A348-I352 HydrophobicContact CB-CD1 4.2Å; S349-I352 WeakPolarHBondContact O-CB 3.47Å; S349-I352 PolarHBondContact O-N 2.88Å; S350-I352 PolarHBondContact O-N 2.91Å; I352-H354 VanDerWaalsContact C-N 3.29Å; I352-H354 PolarHBondContact O-N 3.11Å; I352-I409 HydrophobicContact CD1-CD1 4.47Å
353L93.5Very high95.8Very high43 Ų4345 Ų4523%0.22526%0.264CS..Hα-helixtrans-71.3-24.3178.3-69.797.3000112.6F345 A348 S350 D355 P361F345-L353 HydrophobicContact CB-CD1 4.37Å; F345-L353 HydrophobicContact CB-CG 4.29Å; A348-L353 HydrophobicContact CB-CD1 4.5Å; S350-L353 PolarHBondContact O-N 3.35Å; L353-D355 VanDerWaalsContact C-N 3.29Å; L353-D355 PolarHBondContact O-N 2.75Å; L353-P361 HydrophobicContact CD2-CG 4.01Å
354H92.9Very high95.5Very high125 Ų12552.6 Ų52.658%0.57930%0.299SS*.THydrogen-bonded Turntrans-77.4-13-176.3-66.2-175.7000114H82 S350 I352H82-H354 PolarHBondContact CE1-O 2.77Å; H82-H354 PolarHBondContact ND1-O 2.94Å; S350-H354 PolarHBondContact O-CD2 3.25Å; S350-H354 PolarHBondContact O-N 2.91Å; I352-H354 VanDerWaalsContact C-N 3.29Å; I352-H354 PolarHBondContact O-N 3.11Å
355D92.4Very high95.4Very high21 Ų2156.1 Ų56.111%0.11232%0.316CS..THydrogen-bonded Turntrans-85.6-9-177.7-68.4-26.7000113.4L353 K406 Y408L353-D355 VanDerWaalsContact C-N 3.29Å; L353-D355 PolarHBondContact O-N 2.75Å; D355-K406 WeakPolarHBondContact OD1-CE 3.38Å; D355-K406 IonicContact OD1-NZ 3.71Å; D355-K406 PolarHBondContact OD1-NZ 2.86Å; D355-Y408 HydrophobicContact CB-CD2 4.08Å; D355-Y408 HydrophobicContact CB-CG 4.22Å; D355-Y408 VanDerWaalsContact OD2-CB 3.27Å; D355-Y408 WeakPolarHBondContact OD2-CB 3.49Å
356V95.1Very high95.4Very high8 Ų856.1 Ų56.15%0.04832%0.316CS..SBendtrans-141151.9177.4-64.40000110.5P83 L85 F345 L359 Y408 P411P83-V356 HydrophobicContact CG-CG1 4.38Å; L85-V356 HydrophobicContact CD1-CB 4.04Å; L85-V356 HydrophobicContact CD1-CG1 4.23Å; L85-V356 HydrophobicContact CD1-CG2 4.36Å; F345-V356 HydrophobicContact CE2-CG2 4.45Å; V356-L359 HydrophobicContact CG2-CD1 3.44Å; V356-L359 VanDerWaalsContact CG2-CD1 3.44Å; V356-L359 HydrophobicContact CG2-CG 3.9Å; V356-Y408 HydrophobicContact CG1-CE2 4.5Å; V356-P411 HydrophobicContact CG2-CG 4.5Å
357E96.9Very high95.4Very high93 Ų9357.1 Ų57.144%0.43532%0.32SS..BIsolated β-bridgetrans-107.6150.4176.4-68.7176.5-13700110.5P83 K84 L85P83-E357 PolarHBondContact O-N 3.24Å; K84-E357 HydrophobicContact CB-CB 4.49Å; K84-E357 WeakPolarHBondContact CE-OE2 3.3Å; K84-E357 HydrophobicContact CG-CB 3.9Å; K84-E357 HydrophobicContact CG-CG 4.46Å; L85-E357 PolarHBondContact N-O 3.01Å
358G96.3Very high95.5Very high56 Ų5655.6 Ų55.658%0.57731%0.314SS*.SBendtrans97.67.617500000116
359L97.4Very high95.6Very high28 Ų2855.6 Ų55.615%0.14731%0.311CS..  trans-89.1139.5174.2-57.1-175.2000112.1F68 L85 H344 F345 V356 P411F68-L359 HydrophobicContact CD1-CD2 4.17Å; F68-L359 HydrophobicContact CE1-CD2 3.54Å; F68-L359 HydrophobicContact CZ-CD2 3.81Å; L85-L359 HydrophobicContact CD1-CD2 4.43Å; H344-L359 HydrophobicContact CB-CB 4.38Å; H344-L359 WeakPolarHBondContact ND1-CA 3.47Å; F345-L359 HydrophobicContact CD2-CD1 3.27Å; F345-L359 HydrophobicContact CE2-CD1 3.59Å; F345-L359 HydrophobicContact CG-CD1 4.39Å; V356-L359 HydrophobicContact CG2-CD1 3.44Å; V356-L359 VanDerWaalsContact CG2-CD1 3.44Å; V356-L359 HydrophobicContact CG2-CG 3.9Å; L359-P411 HydrophobicContact CD2-CG 4.46Å
360S96.6Very high95.7Very high84 Ų8455 Ų5559%0.58731%0.306SS*.  trans-138.282.6179.4-179.90000110.4H344 N362 H366H344-S360 PolarHBondContact ND1-N 3.24Å; S360-N362 PolarHBondContact O-N 2.93Å; S360-H366 PolarHBondContact O-CE1 2.91Å; S360-H366 VanDerWaalsContact O-CE1 3.31Å
361P97.1Very high95.9Very high55 Ų5551.1 Ų51.136%0.35728%0.279SS..  trans-63.8132.8179.326.6-34.5000112H344 L346 L353H344-P361 HydrophobicContact CB-CB 4.24Å; L346-P361 HydrophobicContact CB-CB 4.21Å; L346-P361 HydrophobicContact CD1-CB 4.1Å; L353-P361 HydrophobicContact CD2-CG 4.01Å
362N97.2Very high96.2Very high71 Ų7149.2 Ų49.238%0.3827%0.266SS..  trans-136.3129.8177.5179.1-72.8000109.3S360 E364 E365 H366S360-N362 PolarHBondContact O-N 2.93Å; N362-E364 WeakPolarHBondContact OD1-CB 3.28Å; N362-E364 PolarHBondContact OD1-N 2.64Å; N362-E365 HydrophobicContact CB-CB 4.07Å; N362-E365 PolarHBondContact OD1-N 3.06Å; N362-H366 PolarHBondContact N-ND1 3.01Å; N362-H366 VanDerWaalsContact N-ND1 3.17Å; N362-H366 WeakPolarHBondContact O-CB 3.41Å; N362-H366 PolarHBondContact O-N 2.92Å
363E95.4Very high96.3Very high122 Ų12249 Ų4957%0.5726%0.264SS*.Hα-helixtrans-64.2-47.3-177.1-75-176.5178.900112.4L346 H347 E365 H366 E367L346-E363 HydrophobicContact CD1-CG 3.9Å; L346-E363 HydrophobicContact CD2-CG 4.43Å; H347-E363 IonicContact CE1-OE1 3.89Å; H347-E363 PolarHBondContact CE1-OE1 3.28Å; E363-E365 VanDerWaalsContact C-N 3.32Å; E363-E365 PolarHBondContact O-N 3.37Å; E363-H366 PolarHBondContact O-N 3.45Å; E363-E367 WeakPolarHBondContact O-CB 3.13Å; E363-E367 WeakPolarHBondContact O-CG 3.34Å; E363-E367 PolarHBondContact O-N 3.47Å
364E93.7Very high96.5Very high160 Ų16047.9 Ų47.975%0.74826%0.26SS*.Hα-helixtrans-62.6-39-178.2-172.8176.1-175.400112.2N362 R385N362-E364 WeakPolarHBondContact OD1-CB 3.28Å; N362-E364 PolarHBondContact OD1-N 2.64Å; E364-R385 PolarHBondContact O-NH1 2.9Å; E364-R385 PolarHBondContact O-NH2 3.43Å
365E96.7Very high96.5Very high84 Ų8444 Ų4439%0.39324%0.243SC..Hα-helixtrans-81-31.8-179.5-165.2177.8178.400113.2N362 E363 R385N362-E365 HydrophobicContact CB-CB 4.07Å; N362-E365 PolarHBondContact OD1-N 3.06Å; E363-E365 VanDerWaalsContact C-N 3.32Å; E363-E365 PolarHBondContact O-N 3.37Å; E365-R385 VanDerWaalsContact C-CZ 3.5Å; E365-R385 WeakPolarHBondContact O-CD 3.39Å; E365-R385 PolarHBondContact O-NE 3.14Å; E365-R385 PolarHBondContact O-NH1 3.31Å; E365-R385 PolarHBondContact O-NH2 3.25Å
366H98.3Very high96.5Very high1 Ų143.2 Ų43.21%0.00524%0.239CC..Hα-helixtrans-116.1-4.8-167.5-53154.5000114.8P343 H344 L346 S360 N362 E363P343-H366 HydrophobicContact CB-CB 3.79Å; P343-H366 WeakPolarHBondContact CD-O 3.41Å; P343-H366 HydrophobicContact CG-CB 3.99Å; P343-H366 PolarHBondContact O-ND1 2.76Å; H344-H366 AromaticContact CD2-CE1 3.15Å; H344-H366 PolarHBondContact CD2-CE1 3.06Å; H344-H366 AromaticContact CD2-ND1 3.91Å; H344-H366 AromaticContact CD2-NE2 3.37Å; H344-H366 PolarHBondContact CD2-NE2 3.07Å; H344-H366 AromaticContact CG-CE1 3.55Å; L346-H366 HydrophobicContact CB-CB 4.15Å; L346-H366 HydrophobicContact CD2-CB 3.85Å; S360-H366 PolarHBondContact O-CE1 2.91Å; S360-H366 VanDerWaalsContact O-CE1 3.31Å; N362-H366 PolarHBondContact N-ND1 3.01Å; N362-H366 VanDerWaalsContact N-ND1 3.17Å; N362-H366 WeakPolarHBondContact O-CB 3.41Å; N362-H366 PolarHBondContact O-N 2.92Å; E363-H366 PolarHBondContact O-N 3.45Å
367E97.1Very high96.5Very high30 Ų3042.9 Ų42.914%0.1424%0.236CC..  trans-68152.9173.872.7178.1179.900112.4Q279 E363 R385Q279-E367 PolarHBondContact NE2-OE2 3.35Å; E363-E367 WeakPolarHBondContact O-CB 3.13Å; E363-E367 WeakPolarHBondContact O-CG 3.34Å; E363-E367 PolarHBondContact O-N 3.47Å; E367-R385 WeakPolarHBondContact O-CD 3.1Å; E367-R385 PolarHBondContact O-NH1 3.07Å
368T97.7Very high96.5Very high13 Ų1339.5 Ų39.58%0.0822%0.22CC..  trans-100.4130.7168.6-74.20000109.7T293 V294 A383 R385T293-T368 WeakPolarHBondContact CA-O 3.29Å; V294-T368 HydrophobicContact CG2-CG2 3.84Å; V294-T368 PolarHBondContact N-O 3.33Å; V294-T368 VanDerWaalsContact N-O 3.11Å; T368-A383 VanDerWaalsContact CA-O 3.31Å; T368-A383 WeakPolarHBondContact CA-O 3.03Å; T368-R385 PolarHBondContact OG1-N 3.17Å; T368-R385 PolarHBondContact OG1-O 3.31Å; T368-R385 VanDerWaalsContact OG1-O 3.11Å
369F98.1Very high96.5Very high16 Ų1637.7 Ų37.77%0.0720%0.198CC..EExtended strand (participates in β ladder)trans-138.8155.5179.575.8-96.8000113.5R291 F292 T293 D371 Q381 F382 A383R291-F369 HydrophobicContact CG-CB 4.15Å; F292-F369 CarbonylContact O-C 3.58Å; F292-F369 VanDerWaalsContact O-CA 3.29Å; F292-F369 WeakPolarHBondContact O-CA 3.35Å; T293-F369 HydrophobicContact CG2-CB 3.9Å; F369-D371 WeakPolarHBondContact CE2-OD2 3.27Å; F369-Q381 HydrophobicContact CE2-CG 4Å; F369-Q381 HydrophobicContact CZ-CG 4.43Å; F369-F382 WeakPolarHBondContact O-CA 3.46Å; F369-F382 WeakPolarHBondContact O-CB 3.44Å; F369-A383 HydrophobicContact CD1-CB 3.88Å; F369-A383 HydrophobicContact CE1-CB 3.4Å; F369-A383 HydrophobicContact CZ-CB 3.83Å; F369-A383 PolarHBondContact N-O 2.98Å; F369-A383 PolarHBondContact O-N 3.28Å
370L98.3Very high96.4Very high15 Ų1537 Ų378%0.07920%0.195CC..EExtended strand (participates in β ladder)trans-130.3120.2175.3-62.6155.7000107.9F253 F265 F292 I372 T379 F382F253-L370 HydrophobicContact CE2-CD1 4.37Å; F253-L370 HydrophobicContact CZ-CD1 4.14Å; F265-L370 HydrophobicContact CD1-CD1 4.11Å; F265-L370 HydrophobicContact CE1-CD1 3.59Å; F265-L370 HydrophobicContact CZ-CD1 3.84Å; F292-L370 PolarHBondContact N-O 2.75Å; F292-L370 PolarHBondContact O-N 2.88Å; L370-I372 HydrophobicContact CB-CD1 4.17Å; L370-I372 HydrophobicContact CB-CG1 4.18Å; L370-T379 HydrophobicContact CB-CG2 4.35Å; L370-T379 HydrophobicContact CD2-CG2 3.79Å; L370-F382 HydrophobicContact CD2-CB 3.82Å; L370-F382 HydrophobicContact CD2-CG 4.5Å
371D98.3Very high96.4Very high0 Ų035.1 Ų35.10%018%0.176CC..EExtended strand (participates in β ladder)trans-98.9108.6173.9-65.9-26.5000109.2L289 Y290 R291 F369 L380 Q381L289-D371 HydrophobicContact CB-CB 4.12Å; L289-D371 HydrophobicContact CD1-CB 3.67Å; Y290-D371 WeakPolarHBondContact O-CA 3.22Å; R291-D371 VanDerWaalsContact CA-OD1 3.3Å; R291-D371 WeakPolarHBondContact CA-OD1 3.27Å; R291-D371 WeakPolarHBondContact CB-OD1 3.31Å; R291-D371 WeakPolarHBondContact CG-OD1 3.41Å; R291-D371 IonicContact CZ-OD1 3.8Å; R291-D371 IonicContact CZ-OD2 3.07Å; R291-D371 IonicContact NE-OD1 3.27Å; R291-D371 PolarHBondContact NE-OD1 2.94Å; R291-D371 IonicContact NE-OD2 2.86Å; R291-D371 IonicContact NH2-OD1 2.82Å; R291-D371 IonicContact NH2-OD2 3.42Å; R291-D371 PolarHBondContact NH2-OD2 3.39Å; F369-D371 WeakPolarHBondContact CE2-OD2 3.27Å; D371-L380 PolarHBondContact O-N 3.44Å; D371-Q381 HydrophobicContact CB-CB 4.05Å; D371-Q381 PolarHBondContact N-O 2.95Å; D371-Q381 PolarHBondContact O-N 2.92Å; D371-Q381 PolarHBondContact OD2-OE1 2.82Å
372I97.9Very high96.4Very high0 Ų034.4 Ų34.40%017%0.168CC..EExtended strand (participates in β ladder)trans-110.4132.6-167.3-60.1166.8000109.7F253 V257 L263 L289 Y290 F292 L370 F378F253-I372 HydrophobicContact CD2-CD1 3.51Å; F253-I372 HydrophobicContact CD2-CG1 4.16Å; F253-I372 HydrophobicContact CD2-CG2 4.47Å; F253-I372 HydrophobicContact CE2-CD1 3.41Å; F253-I372 VanDerWaalsContact CE2-CD1 3.41Å; F253-I372 HydrophobicContact CE2-CG1 4.16Å; F253-I372 HydrophobicContact CG-CD1 4.43Å; F253-I372 HydrophobicContact CZ-CD1 4.28Å; V257-I372 HydrophobicContact CG2-CG2 4.19Å; L263-I372 HydrophobicContact CD1-CD1 3.21Å; L289-I372 CarbonylContact C-O 3.55Å; L289-I372 WeakPolarHBondContact CA-O 3.18Å; Y290-I372 PolarHBondContact N-O 3.38Å; Y290-I372 PolarHBondContact O-N 2.9Å; F292-I372 HydrophobicContact CB-CD1 4.44Å; F292-I372 HydrophobicContact CD2-CD1 3.76Å; F292-I372 HydrophobicContact CD2-CG1 4.47Å; F292-I372 HydrophobicContact CE2-CD1 4.32Å; F292-I372 HydrophobicContact CG-CD1 4.25Å; L370-I372 HydrophobicContact CB-CD1 4.17Å; L370-I372 HydrophobicContact CB-CG1 4.18Å; I372-F378 WeakPolarHBondContact CA-O 3.44Å
373E96.4Very high96.5Very high4 Ų431.2 Ų31.22%0.01915%0.151CC..  trans-77.6119.7172.7-164.3-76.4131.700109.5I287 L289 I375 T376 G377 F378 L380 F429I287-E373 HydrophobicContact CG2-CG 3.92Å; L289-E373 HydrophobicContact CD2-CB 3.59Å; L289-E373 HydrophobicContact CD2-CG 4.04Å; E373-I375 VanDerWaalsContact C-N 3.34Å; E373-I375 PolarHBondContact O-N 3.1Å; E373-I375 VanDerWaalsContact OE1-CB 3.32Å; E373-I375 WeakPolarHBondContact OE1-CB 3.4Å; E373-I375 WeakPolarHBondContact OE1-CG1 3.48Å; E373-I375 PolarHBondContact OE1-N 3.4Å; E373-I375 PolarHBondContact OE2-N 3.37Å; E373-T376 VanDerWaalsContact OE2-CB 3.28Å; E373-T376 WeakPolarHBondContact OE2-CB 3.36Å; E373-T376 WeakPolarHBondContact OE2-CG2 3.26Å; E373-T376 PolarHBondContact OE2-N 3.46Å; E373-T376 PolarHBondContact OE2-OG1 3.06Å; E373-G377 WeakPolarHBondContact O-CA 3.41Å; E373-G377 PolarHBondContact O-N 3.4Å; E373-F378 PolarHBondContact N-O 2.9Å; E373-L380 HydrophobicContact CB-CD1 4.04Å; E373-L380 HydrophobicContact CB-CG 4.26Å; E373-F429 HydrophobicContact CB-CZ 4.16Å; E373-F429 HydrophobicContact CG-CE1 3.75Å; E373-F429 HydrophobicContact CG-CZ 3.64Å
374P95.8Very high96.6Very high20 Ų2026.8 Ų26.813%0.1313%0.13CC..THydrogen-bonded Turntrans-69.8-26-164.126-35.5000114.5F256 V257 Y290F256-P374 CarbonylContact C-O 3.56Å; F256-P374 WeakPolarHBondContact CA-O 3.28Å; F256-P374 PolarHBondContact N-O 2.89Å; F256-P374 VanDerWaalsContact N-O 3.15Å; V257-P374 PolarHBondContact N-O 2.83Å; Y290-P374 HydrophobicContact CD2-CB 3.8Å; Y290-P374 HydrophobicContact CD2-CG 4.48Å; Y290-P374 HydrophobicContact CE1-CG 4.44Å; Y290-P374 HydrophobicContact CE2-CB 3.58Å; Y290-P374 HydrophobicContact CE2-CG 4.24Å; Y290-P374 HydrophobicContact CG-CB 4.41Å
375I93.3Very high96.8Very high44 Ų4420.7 Ų20.723%0.22610%0.101CC..THydrogen-bonded Turntrans-77.8-48.9-177.4-59.8175000110.1I38 P255 F256 E373 V437I38-I375 HydrophobicContact CB-CG2 4.47Å; I38-I375 HydrophobicContact CD1-CG2 3.8Å; I38-I375 HydrophobicContact CG1-CG2 3.69Å; I38-I375 HydrophobicContact CG2-CG2 4.07Å; P255-I375 WeakPolarHBondContact CA-O 2.97Å; P255-I375 WeakPolarHBondContact CB-O 3.21Å; F256-I375 HydrophobicContact CE1-CG2 4.46Å; F256-I375 PolarHBondContact N-O 3.15Å; E373-I375 VanDerWaalsContact C-N 3.34Å; E373-I375 PolarHBondContact O-N 3.1Å; E373-I375 VanDerWaalsContact OE1-CB 3.32Å; E373-I375 WeakPolarHBondContact OE1-CB 3.4Å; E373-I375 WeakPolarHBondContact OE1-CG1 3.48Å; E373-I375 PolarHBondContact OE1-N 3.4Å; E373-I375 PolarHBondContact OE2-N 3.37Å; I375-V437 HydrophobicContact CD1-CG1 4.14Å; I375-V437 HydrophobicContact CD1-CG2 4.17Å
376T93.6Very high96.9Very high4 Ų417.3 Ų17.33%0.0259%0.085CC..THydrogen-bonded Turntrans-87.6-26.3-175.958.70000113.7I38 T42 E373 F378 F429 V433I38-T376 HydrophobicContact CD1-CG2 4.33Å; T42-T376 HydrophobicContact CG2-CG2 4.4Å; E373-T376 VanDerWaalsContact OE2-CB 3.28Å; E373-T376 WeakPolarHBondContact OE2-CB 3.36Å; E373-T376 WeakPolarHBondContact OE2-CG2 3.26Å; E373-T376 PolarHBondContact OE2-N 3.46Å; E373-T376 PolarHBondContact OE2-OG1 3.06Å; T376-F378 VanDerWaalsContact C-N 3.31Å; T376-F378 HydrophobicContact CG2-CD2 4.48Å; T376-F378 HydrophobicContact CG2-CE2 4.41Å; T376-F378 PolarHBondContact OG1-N 3.41Å; T376-F429 HydrophobicContact CG2-CE2 4.09Å; T376-F429 HydrophobicContact CG2-CZ 3.95Å; T376-V433 HydrophobicContact CG2-CG1 4.03Å; T376-V433 HydrophobicContact CG2-CG2 4.36Å
377G95.4Very high96.9Very high0 Ų017.3 Ų17.30%09%0.085CC..  trans78.99.6-173.200000114.1S252 F253 E373S252-G377 CarbonylContact C-O 3.44Å; S252-G377 WeakPolarHBondContact CA-O 3.4Å; F253-G377 PolarHBondContact N-O 2.88Å; E373-G377 WeakPolarHBondContact O-CA 3.41Å; E373-G377 PolarHBondContact O-N 3.4Å
378F95.4Very high97Very high22 Ų2216.9 Ų16.910%0.0968%0.084CC..BIsolated β-bridgetrans-79135.4179.9-60.9-18.4000112T42 I49 A50 I372 E373 T376 L380 F429T42-F378 HydrophobicContact CG2-CE1 4.33Å; T42-F378 HydrophobicContact CG2-CZ 4.16Å; I49-F378 HydrophobicContact CG2-CE2 4.16Å; A50-F378 HydrophobicContact CB-CE1 4.16Å; A50-F378 HydrophobicContact CB-CZ 3.91Å; I372-F378 WeakPolarHBondContact CA-O 3.44Å; E373-F378 PolarHBondContact N-O 2.9Å; T376-F378 VanDerWaalsContact C-N 3.31Å; T376-F378 HydrophobicContact CG2-CD2 4.48Å; T376-F378 HydrophobicContact CG2-CE2 4.41Å; T376-F378 PolarHBondContact OG1-N 3.41Å; F378-L380 HydrophobicContact CB-CD2 3.75Å; F378-L380 PolarHBondContact O-N 2.86Å; F378-F429 HydrophobicContact CD2-CE2 4.01Å
379T96.3Very high97Very high19 Ų1916.3 Ų16.312%0.1178%0.081CC..EExtended strand (participates in β ladder)trans-78.6110.1170.5-56.90000108.8G250 A251 L370 F382G250-T379 PolarHBondContact O-OG1 2.95Å; A251-T379 VanDerWaalsContact O-CB 3.32Å; A251-T379 WeakPolarHBondContact O-CB 3.17Å; A251-T379 PolarHBondContact O-N 3.18Å; A251-T379 PolarHBondContact O-OG1 3.19Å; L370-T379 HydrophobicContact CB-CG2 4.35Å; L370-T379 HydrophobicContact CD2-CG2 3.79Å; T379-F382 HydrophobicContact CG2-CB 3.91Å; T379-F382 HydrophobicContact CG2-CD1 4.18Å; T379-F382 HydrophobicContact CG2-CG 4.43Å
380L95.6Very high97Very high14 Ų1416 Ų167%0.0738%0.08CC..EExtended strand (participates in β ladder)trans-100.7-18.3-175.4-57.9-164.4000113.3I287 L289 D371 E373 F378 I421 F429I287-L380 HydrophobicContact CD1-CD1 3.98Å; I287-L380 HydrophobicContact CG2-CD1 4.03Å; L289-L380 HydrophobicContact CD1-CB 4.1Å; L289-L380 HydrophobicContact CD2-CB 4.26Å; L289-L380 HydrophobicContact CD2-CD1 3.93Å; L289-L380 HydrophobicContact CD2-CG 4.2Å; D371-L380 PolarHBondContact O-N 3.44Å; E373-L380 HydrophobicContact CB-CD1 4.04Å; E373-L380 HydrophobicContact CB-CG 4.26Å; F378-L380 HydrophobicContact CB-CD2 3.75Å; F378-L380 PolarHBondContact O-N 2.86Å; L380-I421 HydrophobicContact CB-CB 4.34Å; L380-I421 HydrophobicContact CB-CG2 4.21Å; L380-I421 HydrophobicContact CD1-CD1 4.16Å; L380-I421 HydrophobicContact CD2-CD1 4.21Å; L380-I421 PolarHBondContact O-N 3.48Å; L380-F429 HydrophobicContact CD1-CD1 4.4Å; L380-F429 HydrophobicContact CD1-CE1 4.3Å; L380-F429 HydrophobicContact CD1-CE2 4.47Å; L380-F429 HydrophobicContact CD1-CZ 4.33Å
381Q97.3Very high97Very high43 Ų4315.6 Ų15.620%0.2018%0.078CC..EExtended strand (participates in β ladder)trans-145.4143.8168.2170.7176.321.800109F369 D371 A419 V420F369-Q381 HydrophobicContact CE2-CG 4Å; F369-Q381 HydrophobicContact CZ-CG 4.43Å; D371-Q381 HydrophobicContact CB-CB 4.05Å; D371-Q381 PolarHBondContact N-O 2.95Å; D371-Q381 PolarHBondContact O-N 2.92Å; D371-Q381 PolarHBondContact OD2-OE1 2.82Å; Q381-A419 VanDerWaalsContact CA-O 3.27Å; Q381-A419 WeakPolarHBondContact CA-O 3.27Å; Q381-V420 HydrophobicContact CG-CG2 4Å
382F97.6Very high96.9Very high40 Ų4015.6 Ų15.618%0.1758%0.078CC..EExtended strand (participates in β ladder)trans-153.6158.7171.672-86.5000111.5V61 F369 L370 T379 K384 E417 S418 A419V61-F382 HydrophobicContact CG1-CZ 3.99Å; F369-F382 WeakPolarHBondContact O-CA 3.46Å; F369-F382 WeakPolarHBondContact O-CB 3.44Å; L370-F382 HydrophobicContact CD2-CB 3.82Å; L370-F382 HydrophobicContact CD2-CG 4.5Å; T379-F382 HydrophobicContact CG2-CB 3.91Å; T379-F382 HydrophobicContact CG2-CD1 4.18Å; T379-F382 HydrophobicContact CG2-CG 4.43Å; F382-K384 HydrophobicContact CD2-CB 4.25Å; F382-K384 HydrophobicContact CE2-CB 4.33Å; F382-E417 WeakPolarHBondContact CD2-O 3.47Å; F382-E417 HydrophobicContact CE2-CG 4.07Å; F382-E417 WeakPolarHBondContact CE2-O 3.3Å; F382-E417 HydrophobicContact CZ-CG 4.37Å; F382-S418 WeakPolarHBondContact O-CA 3.45Å; F382-S418 VanDerWaalsContact O-CB 3.25Å; F382-S418 WeakPolarHBondContact O-CB 3.43Å; F382-A419 HydrophobicContact CD1-CB 4.03Å; F382-A419 HydrophobicContact CE1-CB 3.45Å; F382-A419 VanDerWaalsContact CE1-CB 3.45Å; F382-A419 HydrophobicContact CZ-CB 4.08Å; F382-A419 PolarHBondContact N-O 3.34Å; F382-A419 PolarHBondContact O-N 3.07Å
383A98.3Very high96.8Very high4 Ų419.4 Ų19.43%0.0339%0.094CC..EExtended strand (participates in β ladder)trans-135.2111.6163.800000108.2T368 F369 R385T368-A383 VanDerWaalsContact CA-O 3.31Å; T368-A383 WeakPolarHBondContact CA-O 3.03Å; F369-A383 HydrophobicContact CD1-CB 3.88Å; F369-A383 HydrophobicContact CE1-CB 3.4Å; F369-A383 HydrophobicContact CZ-CB 3.83Å; F369-A383 PolarHBondContact N-O 2.98Å; F369-A383 PolarHBondContact O-N 3.28Å; A383-R385 HydrophobicContact CB-CG 4.38Å
384K97.9Very high96.6Very high29 Ų2921.5 Ų21.513%0.12611%0.108CC..EExtended strand (participates in β ladder)trans-96110.3173.3174.2-175.1179173.90108S267 D269 F382 L386 E417S267-K384 PolarHBondContact OG-NZ 2.94Å; D269-K384 IonicContact OD2-NZ 3.95Å; D269-K384 PolarHBondContact OD2-NZ 3.43Å; F382-K384 HydrophobicContact CD2-CB 4.25Å; F382-K384 HydrophobicContact CE2-CB 4.33Å; K384-L386 HydrophobicContact CD-CD1 4.39Å; K384-L386 HydrophobicContact CG-CD1 4.31Å; K384-L386 HydrophobicContact CG-CG 4.29Å; K384-E417 HydrophobicContact CB-CB 4.27Å; K384-E417 PolarHBondContact N-O 3Å; K384-E417 PolarHBondContact O-N 2.77Å
385R98.3Very high96.5Very high33 Ų3321 Ų2113%0.12511%0.105CC..EExtended strand (participates in β ladder)trans-116.5120.9-174.7-53.7-171.4-172.3140.3-24.7110.5P343 E364 E365 E367 T368 A383 L415 N416P343-R385 HydrophobicContact CG-CB 3.86Å; E364-R385 PolarHBondContact O-NH1 2.9Å; E364-R385 PolarHBondContact O-NH2 3.43Å; E365-R385 VanDerWaalsContact C-CZ 3.5Å; E365-R385 WeakPolarHBondContact O-CD 3.39Å; E365-R385 PolarHBondContact O-NE 3.14Å; E365-R385 PolarHBondContact O-NH1 3.31Å; E365-R385 PolarHBondContact O-NH2 3.25Å; E367-R385 WeakPolarHBondContact O-CD 3.1Å; E367-R385 PolarHBondContact O-NH1 3.07Å; T368-R385 PolarHBondContact OG1-N 3.17Å; T368-R385 PolarHBondContact OG1-O 3.31Å; T368-R385 VanDerWaalsContact OG1-O 3.11Å; A383-R385 HydrophobicContact CB-CG 4.38Å; R385-L415 VanDerWaalsContact CA-O 3.28Å; R385-L415 WeakPolarHBondContact CA-O 3.46Å; R385-N416 HydrophobicContact CG-CB 4.42Å
386L97.8Very high96.2Very high13 Ų1324.6 Ų24.67%0.06813%0.132CC..EExtended strand (participates in β ladder)trans-139.6148.2-174.5-59.4170.7000109.7I270 I340 K384 W414 L415I270-L386 HydrophobicContact CG2-CD1 3.84Å; I270-L386 HydrophobicContact CG2-CD2 3.78Å; I270-L386 HydrophobicContact CG2-CG 4.47Å; I340-L386 HydrophobicContact CG2-CD2 4.17Å; K384-L386 HydrophobicContact CD-CD1 4.39Å; K384-L386 HydrophobicContact CG-CD1 4.31Å; K384-L386 HydrophobicContact CG-CG 4.29Å; L386-W414 CarbonylContact O-C 3.57Å; L386-W414 VanDerWaalsContact O-CA 3.23Å; L386-W414 WeakPolarHBondContact O-CA 3.33Å; L386-W414 WeakPolarHBondContact O-CB 3.13Å; L386-L415 HydrophobicContact CB-CD1 4.39Å; L386-L415 HydrophobicContact CB-CG 4.27Å; L386-L415 PolarHBondContact N-O 2.91Å; L386-L415 VanDerWaalsContact N-O 3.12Å; L386-L415 PolarHBondContact O-N 3.17Å
387Q98.8Very high96Very high0 Ų029.9 Ų29.90%015%0.154CC..EExtended strand (participates in β ladder)trans-116.9134171.3-178172.4-72.300110.4F68 I340 S341 F345 N389 P411 L413 W414F68-Q387 HydrophobicContact CE2-CG 4.34Å; I340-Q387 WeakPolarHBondContact CA-O 3.48Å; S341-Q387 PolarHBondContact N-O 3.23Å; S341-Q387 PolarHBondContact O-N 3.37Å; S341-Q387 WeakPolarHBondContact OG-CB 3.4Å; S341-Q387 PolarHBondContact OG-NE2 2.94Å; F345-Q387 VanDerWaalsContact CE1-NE2 3.34Å; Q387-N389 WeakPolarHBondContact CG-OD1 3.39Å; Q387-N389 PolarHBondContact NE2-OD1 2.85Å; Q387-N389 PolarHBondContact O-ND2 3.36Å; Q387-P411 HydrophobicContact CG-CB 4.46Å; Q387-L413 WeakPolarHBondContact CA-O 3.46Å; Q387-L413 WeakPolarHBondContact CG-O 3.24Å; Q387-W414 HydrophobicContact CB-CB 3.85Å; Q387-W414 HydrophobicContact CG-CB 4.09Å
388V98.8Very high96Very high21 Ų2129.9 Ų29.913%0.12715%0.154CC..EExtended strand (participates in β ladder)trans-99.8126.2175.2-175.60000108.5V199 V338 I340 I412 L413V199-V388 HydrophobicContact CG1-CB 4.29Å; V199-V388 HydrophobicContact CG1-CG1 4Å; V199-V388 HydrophobicContact CG1-CG2 4.19Å; V338-V388 HydrophobicContact CG1-CG1 4.11Å; I340-V388 HydrophobicContact CD1-CG2 4.12Å; V388-I412 WeakPolarHBondContact O-CB 3.29Å; V388-I412 PolarHBondContact O-N 3.15Å; V388-L413 HydrophobicContact CB-CD1 4.26Å; V388-L413 HydrophobicContact CG2-CD1 4.07Å; V388-L413 PolarHBondContact N-O 3.29Å; V388-L413 PolarHBondContact O-N 2.91Å
389N98.8Very high96Very high1 Ų134.3 Ų34.31%0.00518%0.175CC..EExtended strand (participates in β ladder)trans-127.8159.8-178.2-42.5-84000110.2V338 F339 S341 F345 Q387 I409 F410 P411V338-N389 WeakPolarHBondContact CA-O 3.47Å; F339-N389 HydrophobicContact CB-CB 4.13Å; F339-N389 PolarHBondContact N-O 2.91Å; F339-N389 WeakPolarHBondContact O-CA 3.32Å; F339-N389 WeakPolarHBondContact O-CB 3.39Å; F339-N389 PolarHBondContact O-N 2.91Å; F339-N389 PolarHBondContact O-ND2 2.93Å; S341-N389 PolarHBondContact OG-ND2 3.4Å; F345-N389 WeakPolarHBondContact CE1-OD1 3.19Å; F345-N389 VanDerWaalsContact CZ-OD1 3.28Å; F345-N389 WeakPolarHBondContact CZ-OD1 3.49Å; Q387-N389 WeakPolarHBondContact CG-OD1 3.39Å; Q387-N389 PolarHBondContact NE2-OD1 2.85Å; Q387-N389 PolarHBondContact O-ND2 3.36Å; N389-I409 HydrophobicContact CB-CG2 3.37Å; N389-F410 CarbonylContact C-O 2.97Å; N389-F410 VanDerWaalsContact CA-O 3.25Å; N389-F410 WeakPolarHBondContact CA-O 3.47Å; N389-F410 WeakPolarHBondContact CB-O 3.27Å; N389-P411 VanDerWaalsContact OD1-CA 3.26Å; N389-P411 WeakPolarHBondContact OD1-CA 3.35Å; N389-P411 WeakPolarHBondContact OD1-CB 3.26Å
390L98.2Very high95.9Very high11 Ų1134.4 Ų34.46%0.05818%0.178CC..EExtended strand (participates in β ladder)trans-126.8129.7173.8-155.571.7000109.5L137 L139 V142 P337 V338 V392 F410 I412L137-L390 HydrophobicContact CD2-CB 3.92Å; L137-L390 HydrophobicContact CD2-CD2 3.84Å; L137-L390 HydrophobicContact CD2-CG 4.44Å; L139-L390 HydrophobicContact CD2-CD2 4.09Å; V142-L390 HydrophobicContact CB-CD2 3.76Å; V142-L390 HydrophobicContact CG1-CD2 3.59Å; V142-L390 HydrophobicContact CG1-CG 4.06Å; P337-L390 HydrophobicContact CG-CD1 4.07Å; P337-L390 HydrophobicContact CG-CG 4.25Å; P337-L390 WeakPolarHBondContact O-CD1 3.29Å; V338-L390 HydrophobicContact CG2-CD1 4Å; L390-V392 PolarHBondContact O-N 2.86Å; L390-F410 PolarHBondContact N-O 3.11Å; L390-F410 PolarHBondContact O-N 3.1Å; L390-I412 HydrophobicContact CB-CD1 4.26Å; L390-I412 HydrophobicContact CB-CG1 4.34Å
391L97.8Very high95.9Very high6 Ų634 Ų343%0.03118%0.176CC..EExtended strand (participates in β ladder)trans-76.5118.1175.7170.170.6000109.7I317 P337 F339 K393 P407 I409I317-L391 HydrophobicContact CD1-CD1 4.4Å; I317-L391 HydrophobicContact CD1-CD2 4.07Å; I317-L391 HydrophobicContact CG1-CD2 4Å; I317-L391 HydrophobicContact CG2-CD1 4.14Å; I317-L391 HydrophobicContact CG2-CD2 4.01Å; P337-L391 HydrophobicContact CB-CB 4.17Å; P337-L391 PolarHBondContact O-N 3.37Å; F339-L391 HydrophobicContact CD2-CB 3.76Å; F339-L391 HydrophobicContact CE2-CB 3.51Å; F339-L391 HydrophobicContact CE2-CD2 3.71Å; F339-L391 HydrophobicContact CE2-CG 4.21Å; F339-L391 HydrophobicContact CZ-CB 4.42Å; F339-L391 HydrophobicContact CZ-CD2 4.01Å; L391-K393 HydrophobicContact CD2-CD 4.41Å; L391-K393 HydrophobicContact CD2-CG 4.29Å; L391-K393 HydrophobicContact CG-CG 4.12Å; L391-P407 HydrophobicContact CD1-CB 4.18Å; L391-I409 HydrophobicContact CD1-CG1 4.27Å
392V96.9Very high95.7Very high0 Ų034.8 Ų34.80%019%0.187CC..EExtended strand (participates in β ladder)trans-91.4127173.9-1740000107.7L137 V142 M168 L390 V404 P407 Y408 F410L137-V392 HydrophobicContact CD1-CG2 4.27Å; L137-V392 HydrophobicContact CD2-CG2 4.03Å; V142-V392 HydrophobicContact CG1-CB 4.49Å; V142-V392 HydrophobicContact CG1-CG2 4.12Å; V142-V392 HydrophobicContact CG2-CG2 4.46Å; M168-V392 HydrophobicContact CE-CB 4.41Å; M168-V392 HydrophobicContact CE-CG1 3.54Å; M168-V392 HydrophobicContact CE-CG2 4.06Å; L390-V392 PolarHBondContact O-N 2.86Å; V392-V404 HydrophobicContact CG1-CB 4.44Å; V392-V404 HydrophobicContact CG1-CG1 3.86Å; V392-V404 HydrophobicContact CG1-CG2 3.76Å; V392-P407 WeakPolarHBondContact O-CA 3.49Å; V392-Y408 HydrophobicContact CB-CD1 4.13Å; V392-Y408 HydrophobicContact CB-CE1 3.78Å; V392-Y408 HydrophobicContact CG1-CE1 3.88Å; V392-Y408 HydrophobicContact CG2-CE1 4.32Å; V392-Y408 PolarHBondContact N-O 3.01Å; V392-Y408 PolarHBondContact O-N 3.09Å; V392-F410 HydrophobicContact CG2-CB 3.8Å
393K94.4Very high95.6Very high80 Ų8037.7 Ų37.735%0.34820%0.199SC..  trans-115.9148.5176.4-64.4-172.9179.5-173.90110.6L391 A395 P407L391-K393 HydrophobicContact CD2-CD 4.41Å; L391-K393 HydrophobicContact CD2-CG 4.29Å; L391-K393 HydrophobicContact CG-CG 4.12Å; K393-A395 PolarHBondContact O-N 3.17Å; K393-P407 HydrophobicContact CG-CB 4.47Å
394P93.3Very high95.4Very high48 Ų4838.2 Ų38.231%0.31220%0.202SC..  trans-56.5131.1168.6-24.834.7000111.4V404 Q405P394-V404 WeakPolarHBondContact CB-O 3.24Å; P394-V404 HydrophobicContact CG-CG1 4.17Å; P394-Q405 WeakPolarHBondContact CG-O 3.41Å
395A92.4Very high95.1Very high8 Ų845 Ų457%0.06623%0.234CC..  trans-133.283.1173.500000109.8P145 K393 K397 I398 L401P145-A395 HydrophobicContact CB-CB 4.41Å; K393-A395 PolarHBondContact O-N 3.17Å; A395-K397 PolarHBondContact O-N 3.35Å; A395-I398 HydrophobicContact CB-CB 4.09Å; A395-I398 HydrophobicContact CB-CD1 4.24Å; A395-I398 HydrophobicContact CB-CG1 4.34Å; A395-I398 PolarHBondContact O-N 3.21Å; A395-L401 HydrophobicContact CB-CB 4.06Å; A395-L401 HydrophobicContact CB-CD1 3.89Å
396P86.5Confident94.8Very high120 Ų12048.5 Ų48.578%0.77925%0.25SS*.THydrogen-bonded Turntrans-59-23.2-171.8-26.434.5000115I398P396-I398 VanDerWaalsContact C-N 3.33Å
397K90.9Very high94.7Very high115 Ų11550.6 Ų50.650%0.526%0.264SS..THydrogen-bonded Turntrans-84.2-7.5178.5-64.4-176.4178.7-178.60113.5Q154 N158 A395Q154-K397 HydrophobicContact CB-CB 4.33Å; Q154-K397 HydrophobicContact CB-CD 4.4Å; N158-K397 WeakPolarHBondContact CB-O 3.23Å; N158-K397 PolarHBondContact ND2-O 3.02Å; A395-K397 PolarHBondContact O-N 3.35Å
398I95.1Very high94.5Very high0 Ų051.9 Ų51.90%027%0.269CS..  trans-112.7113.1-178.5-64.6-177.7000108.2P145 L157 N158 M161 A395 P396 A400 L401 S402P145-I398 HydrophobicContact CB-CD1 3.59Å; P145-I398 HydrophobicContact CG-CD1 3.2Å; L157-I398 HydrophobicContact CB-CD1 4.36Å; N158-I398 HydrophobicContact CB-CG1 4.19Å; N158-I398 WeakPolarHBondContact OD1-CA 3.39Å; M161-I398 HydrophobicContact CE-CD1 4.36Å; M161-I398 HydrophobicContact SD-CG2 3.59Å; M161-I398 VanDerWaalsContact SD-CG2 3.59Å; A395-I398 HydrophobicContact CB-CB 4.09Å; A395-I398 HydrophobicContact CB-CD1 4.24Å; A395-I398 HydrophobicContact CB-CG1 4.34Å; A395-I398 PolarHBondContact O-N 3.21Å; P396-I398 VanDerWaalsContact C-N 3.33Å; I398-A400 VanDerWaalsContact C-N 3.26Å; I398-A400 HydrophobicContact CG2-CB 4.08Å; I398-A400 PolarHBondContact O-N 2.97Å; I398-L401 HydrophobicContact CG2-CB 4.35Å; I398-L401 HydrophobicContact CG2-CD1 4.45Å; I398-L401 HydrophobicContact CG2-CG 4.24Å; I398-L401 CarbonylContact O-C 3.57Å; I398-L401 PolarHBondContact O-N 2.93Å; I398-S402 PolarHBondContact O-N 3.09Å; I398-S402 VanDerWaalsContact O-N 3.11Å
399E94.9Very high94.5Very high115 Ų11551.3 Ų51.354%0.53727%0.266SS..G310 helixtrans-58.7-40.7-175.9-173.8174.4145.700111.7N158 K162 L401 S402N158-E399 PolarHBondContact OD1-N 3.36Å; K162-E399 WeakPolarHBondContact CE-OE2 3.45Å; K162-E399 IonicContact NZ-OE2 3.39Å; K162-E399 PolarHBondContact NZ-OE2 2.86Å; E399-L401 PolarHBondContact O-N 2.93Å; E399-L401 VanDerWaalsContact O-N 3.12Å; E399-S402 VanDerWaalsContact O-CB 3.3Å; E399-S402 WeakPolarHBondContact O-CB 3.34Å; E399-S402 PolarHBondContact O-N 3.43Å; E399-S402 VanDerWaalsContact O-N 3.1Å; E399-S402 PolarHBondContact O-OG 3.16Å
400A95.1Very high94.4Very high22 Ų2251.3 Ų51.318%0.18227%0.266CS..G310 helixtrans-59.1-23.8178.600000114V141 M168 I398V141-A400 HydrophobicContact CG1-CB 3.81Å; M168-A400 WeakPolarHBondContact CB-O 3.41Å; I398-A400 VanDerWaalsContact C-N 3.26Å; I398-A400 HydrophobicContact CG2-CB 4.08Å; I398-A400 PolarHBondContact O-N 2.97Å
401L95.5Very high94.5Very high4 Ų450.8 Ų50.82%0.02126%0.263CS..G310 helixtrans-114.98.8-179.7-62.6178000112.6V141 V142 P145 M168 A395 I398 E399 K403 V404V141-L401 HydrophobicContact CG1-CD2 4.23Å; V141-L401 HydrophobicContact CG1-CG 4.26Å; V142-L401 HydrophobicContact CG2-CD2 4.2Å; P145-L401 HydrophobicContact CB-CD1 4.41Å; P145-L401 HydrophobicContact CG-CD1 4Å; M168-L401 HydrophobicContact CB-CD2 4.07Å; M168-L401 HydrophobicContact CG-CD2 3.92Å; M168-L401 HydrophobicContact SD-CD2 3.86Å; A395-L401 HydrophobicContact CB-CB 4.06Å; A395-L401 HydrophobicContact CB-CD1 3.89Å; I398-L401 HydrophobicContact CG2-CB 4.35Å; I398-L401 HydrophobicContact CG2-CD1 4.45Å; I398-L401 HydrophobicContact CG2-CG 4.24Å; I398-L401 CarbonylContact O-C 3.57Å; I398-L401 PolarHBondContact O-N 2.93Å; E399-L401 PolarHBondContact O-N 2.93Å; E399-L401 VanDerWaalsContact O-N 3.12Å; L401-K403 PolarHBondContact O-N 3Å; L401-K403 VanDerWaalsContact O-N 3.15Å; L401-V404 HydrophobicContact CB-CG2 4.44Å; L401-V404 HydrophobicContact CD2-CG2 4.32Å; L401-V404 WeakPolarHBondContact O-CB 3.16Å; L401-V404 PolarHBondContact O-N 2.75Å
402S92.8Very high94.5Very high61 Ų6150.8 Ų50.843%0.42726%0.263SS..THydrogen-bonded Turntrans-64.4-20.5-173.661.50000114.2I398 E399I398-S402 PolarHBondContact O-N 3.09Å; I398-S402 VanDerWaalsContact O-N 3.11Å; E399-S402 VanDerWaalsContact O-CB 3.3Å; E399-S402 WeakPolarHBondContact O-CB 3.34Å; E399-S402 PolarHBondContact O-N 3.43Å; E399-S402 VanDerWaalsContact O-N 3.1Å; E399-S402 PolarHBondContact O-OG 3.16Å
403K94.2Very high94.6Very high100 Ų10050.8 Ų50.844%0.43526%0.263SS..THydrogen-bonded Turntrans-88.2-8.9177.6-56-56.3179.3165.60113.9L77 N78 L401 Q405L77-K403 WeakPolarHBondContact O-CG 3.49Å; N78-K403 WeakPolarHBondContact O-CE 3.42Å; N78-K403 PolarHBondContact O-NZ 3.07Å; L401-K403 PolarHBondContact O-N 3Å; L401-K403 VanDerWaalsContact O-N 3.15Å; K403-Q405 PolarHBondContact O-N 3.26Å
404V94.3Very high94.8Very high16 Ų1647.1 Ų47.110%0.09725%0.247CC..  trans-76.4109.7177.2-178.90000108.8M168 V392 P394 L401 K406 Y408M168-V404 HydrophobicContact CE-CG2 4.02Å; M168-V404 HydrophobicContact SD-CG2 3.72Å; V392-V404 HydrophobicContact CG1-CB 4.44Å; V392-V404 HydrophobicContact CG1-CG1 3.86Å; V392-V404 HydrophobicContact CG1-CG2 3.76Å; P394-V404 WeakPolarHBondContact CB-O 3.24Å; P394-V404 HydrophobicContact CG-CG1 4.17Å; L401-V404 HydrophobicContact CB-CG2 4.44Å; L401-V404 HydrophobicContact CD2-CG2 4.32Å; L401-V404 WeakPolarHBondContact O-CB 3.16Å; L401-V404 PolarHBondContact O-N 2.75Å; V404-K406 WeakPolarHBondContact CG1-O 3.13Å; V404-Y408 HydrophobicContact CG1-CD1 4.5Å; V404-Y408 HydrophobicContact CG1-CE1 4.16Å
405Q91.5Very high95Very high170 Ų17045.2 Ų45.279%0.79423%0.234SC*.  trans-87-39.2-174.9-60.2-177.11900113.1P394 K403P394-Q405 WeakPolarHBondContact CG-O 3.41Å; K403-Q405 PolarHBondContact O-N 3.26Å
406K93.3Very high95.3Very high108 Ų10845.7 Ų45.747%0.4724%0.236SC..SBendtrans-133.6156.5-179.565.3176.3-175.3168.40110.7D355 V404D355-K406 WeakPolarHBondContact OD1-CE 3.38Å; D355-K406 IonicContact OD1-NZ 3.71Å; D355-K406 PolarHBondContact OD1-NZ 2.86Å; V404-K406 WeakPolarHBondContact CG1-O 3.13Å
407P94.7Very high95.9Very high56 Ų5640.2 Ų40.236%0.36420%0.199SC..  trans-64.4139.2171.9-17.831.1000111.4I317 L391 V392 K393I317-P407 HydrophobicContact CD1-CB 3.7Å; I317-P407 HydrophobicContact CD1-CG 3.98Å; L391-P407 HydrophobicContact CD1-CB 4.18Å; V392-P407 WeakPolarHBondContact O-CA 3.49Å; K393-P407 HydrophobicContact CG-CB 4.47Å
408Y95.9Very high96.2Very high27 Ų2736 Ų3611%0.10618%0.184CC..EExtended strand (participates in β ladder)trans-153.6157.6173.771-78000111.7P83 M168 D355 V356 V392 V404 F410P83-Y408 HydrophobicContact CG-CE2 4.36Å; M168-Y408 WeakPolarHBondContact CE-OH 3.34Å; D355-Y408 HydrophobicContact CB-CD2 4.08Å; D355-Y408 HydrophobicContact CB-CG 4.22Å; D355-Y408 VanDerWaalsContact OD2-CB 3.27Å; D355-Y408 WeakPolarHBondContact OD2-CB 3.49Å; V356-Y408 HydrophobicContact CG1-CE2 4.5Å; V392-Y408 HydrophobicContact CB-CD1 4.13Å; V392-Y408 HydrophobicContact CB-CE1 3.78Å; V392-Y408 HydrophobicContact CG1-CE1 3.88Å; V392-Y408 HydrophobicContact CG2-CE1 4.32Å; V392-Y408 PolarHBondContact N-O 3.01Å; V392-Y408 PolarHBondContact O-N 3.09Å; V404-Y408 HydrophobicContact CG1-CD1 4.5Å; V404-Y408 HydrophobicContact CG1-CE1 4.16Å; Y408-F410 HydrophobicContact CE2-CB 4.18Å; Y408-F410 AromaticContact CE2-CD2 3.82Å; Y408-F410 HydrophobicContact CE2-CD2 3.82Å; Y408-F410 HydrophobicContact CE2-CG 4.48Å
409I97.6Very high96.3Very high10 Ų1036.2 Ų36.25%0.05119%0.187CC..EExtended strand (participates in β ladder)trans-94.4110.9-176.3-60.6174.8000108.7V326 F339 F345 I352 N389 L391V326-I409 HydrophobicContact CB-CD1 4.1Å; V326-I409 HydrophobicContact CG1-CD1 3.92Å; V326-I409 HydrophobicContact CG2-CD1 3.83Å; F339-I409 HydrophobicContact CB-CG2 4.24Å; F339-I409 HydrophobicContact CD1-CD1 3.92Å; F339-I409 HydrophobicContact CE1-CD1 4.29Å; F339-I409 HydrophobicContact CG-CD1 4.33Å; F345-I409 HydrophobicContact CE1-CG2 3.97Å; F345-I409 HydrophobicContact CZ-CB 4.43Å; F345-I409 HydrophobicContact CZ-CG2 3.87Å; I352-I409 HydrophobicContact CD1-CD1 4.47Å; N389-I409 HydrophobicContact CB-CG2 3.37Å; L391-I409 HydrophobicContact CD1-CG1 4.27Å
410F98.1Very high96.4Very high1 Ų133.7 Ų33.70%0.00418%0.179CC..EExtended strand (participates in β ladder)trans-91.2119.8-179.6-168.2-68.9000110.2V70 P83 L85 L137 N389 L390 V392 Y408 I412V70-F410 HydrophobicContact CG2-CZ 3.72Å; P83-F410 HydrophobicContact CB-CE2 3.83Å; P83-F410 HydrophobicContact CB-CZ 4.37Å; P83-F410 HydrophobicContact CG-CD2 4.06Å; P83-F410 HydrophobicContact CG-CE2 3.57Å; L85-F410 HydrophobicContact CD2-CE1 4.47Å; L85-F410 HydrophobicContact CD2-CZ 4.02Å; L137-F410 HydrophobicContact CB-CD1 4.07Å; L137-F410 HydrophobicContact CB-CE1 4.04Å; L137-F410 HydrophobicContact CB-CZ 4.46Å; L137-F410 HydrophobicContact CD1-CD2 4.05Å; L137-F410 HydrophobicContact CD1-CE2 4.24Å; L137-F410 HydrophobicContact CD1-CG 4.24Å; L137-F410 HydrophobicContact CD2-CB 4.02Å; L137-F410 HydrophobicContact CD2-CD1 4.1Å; L137-F410 HydrophobicContact CD2-CG 4Å; L137-F410 HydrophobicContact CG-CD1 4.5Å; N389-F410 CarbonylContact C-O 2.97Å; N389-F410 VanDerWaalsContact CA-O 3.25Å; N389-F410 WeakPolarHBondContact CA-O 3.47Å; N389-F410 WeakPolarHBondContact CB-O 3.27Å; L390-F410 PolarHBondContact N-O 3.11Å; L390-F410 PolarHBondContact O-N 3.1Å; V392-F410 HydrophobicContact CG2-CB 3.8Å; Y408-F410 HydrophobicContact CE2-CB 4.18Å; Y408-F410 AromaticContact CE2-CD2 3.82Å; Y408-F410 HydrophobicContact CE2-CD2 3.82Å; Y408-F410 HydrophobicContact CE2-CG 4.48Å; F410-I412 HydrophobicContact CD1-CD1 3.87Å; F410-I412 HydrophobicContact CE1-CD1 4.38Å
411P98.4Very high96.3Very high0 Ų033.1 Ų33.10%017%0.172CC..EExtended strand (participates in β ladder)trans-76.8128.7177.834.2-36.2000111.1F68 L85 F345 V356 L359 Q387 N389F68-P411 HydrophobicContact CD2-CB 3.71Å; F68-P411 HydrophobicContact CD2-CG 4.14Å; F68-P411 HydrophobicContact CE2-CB 3.78Å; F68-P411 HydrophobicContact CE2-CG 4.42Å; F68-P411 HydrophobicContact CG-CG 4.48Å; L85-P411 HydrophobicContact CD1-CG 3.36Å; F345-P411 HydrophobicContact CE2-CB 4.24Å; F345-P411 HydrophobicContact CE2-CG 4.19Å; F345-P411 HydrophobicContact CZ-CB 4.06Å; F345-P411 HydrophobicContact CZ-CG 4.39Å; V356-P411 HydrophobicContact CG2-CG 4.5Å; L359-P411 HydrophobicContact CD2-CG 4.46Å; Q387-P411 HydrophobicContact CG-CB 4.46Å; N389-P411 VanDerWaalsContact OD1-CA 3.26Å; N389-P411 WeakPolarHBondContact OD1-CA 3.35Å; N389-P411 WeakPolarHBondContact OD1-CB 3.26Å
412I98.6Very high96.2Very high5 Ų534.2 Ų34.23%0.02619%0.185CC..EExtended strand (participates in β ladder)trans-94.8-53.8-177.4-54.4-62.1000110.1F68 L137 L139 V199 V388 L390 F410F68-I412 PolarHBondContact N-O 3.07Å; L137-I412 HydrophobicContact CB-CD1 3.66Å; L137-I412 HydrophobicContact CD2-CD1 3.8Å; L137-I412 HydrophobicContact CG-CD1 4.41Å; L139-I412 HydrophobicContact CD2-CD1 3.96Å; L139-I412 HydrophobicContact CD2-CG1 4.38Å; V199-I412 HydrophobicContact CG2-CG2 3.93Å; V388-I412 WeakPolarHBondContact O-CB 3.29Å; V388-I412 PolarHBondContact O-N 3.15Å; L390-I412 HydrophobicContact CB-CD1 4.26Å; L390-I412 HydrophobicContact CB-CG1 4.34Å; F410-I412 HydrophobicContact CD1-CD1 3.87Å; F410-I412 HydrophobicContact CE1-CD1 4.38Å
413L98.8Very high96.2Very high0 Ų036.7 Ų36.70%019%0.193CC..EExtended strand (participates in β ladder)trans-159.3161.3179.86081.8000109.9F65 W66 I67 L178 V199 F200 Q387 V388F65-L413 HydrophobicContact CD1-CD1 4.19Å; W66-L413 CarbonylContact O-C 3.56Å; W66-L413 WeakPolarHBondContact O-CA 3.49Å; W66-L413 VanDerWaalsContact O-CB 3.26Å; W66-L413 WeakPolarHBondContact O-CB 3.31Å; I67-L413 HydrophobicContact CB-CB 4.35Å; I67-L413 HydrophobicContact CG1-CB 3.98Å; I67-L413 HydrophobicContact CG1-CD2 4.31Å; L178-L413 HydrophobicContact CD2-CD2 3.49Å; L178-L413 VanDerWaalsContact CD2-CD2 3.49Å; V199-L413 HydrophobicContact CB-CD2 4.22Å; V199-L413 HydrophobicContact CG1-CD2 4.09Å; V199-L413 HydrophobicContact CG1-CG 4.47Å; V199-L413 HydrophobicContact CG2-CD2 3.99Å; F200-L413 HydrophobicContact CE2-CD1 4.19Å; F200-L413 HydrophobicContact CE2-CD2 4.22Å; F200-L413 HydrophobicContact CZ-CD1 4.22Å; Q387-L413 WeakPolarHBondContact CA-O 3.46Å; Q387-L413 WeakPolarHBondContact CG-O 3.24Å; V388-L413 HydrophobicContact CB-CD1 4.26Å; V388-L413 HydrophobicContact CG2-CD1 4.07Å; V388-L413 PolarHBondContact N-O 3.29Å; V388-L413 PolarHBondContact O-N 2.91Å
414W98.8Very high96Very high4 Ų435.7 Ų35.72%0.01520%0.204CC..EExtended strand (participates in β ladder)trans-122.9159.5162.472.1-92.5000110.8W66 F68 P343 H344 L386 Q387 N416W66-W414 HydrophobicContact CB-CD2 4.1Å; W66-W414 HydrophobicContact CB-CG 4.2Å; W66-W414 HydrophobicContact CB-CZ2 4.03Å; W66-W414 VanDerWaalsContact CB-NE1 3.28Å; W66-W414 HydrophobicContact CD2-CD2 4.3Å; W66-W414 AromaticContact CD2-CE2 3.67Å; W66-W414 AromaticContact CD2-CH2 3.57Å; W66-W414 HydrophobicContact CD2-CH2 3.57Å; W66-W414 AromaticContact CD2-CZ2 3.26Å; W66-W414 HydrophobicContact CD2-CZ2 3.26Å; W66-W414 HydrophobicContact CD2-CZ3 4.21Å; W66-W414 AromaticContact CE2-CH2 3.84Å; W66-W414 AromaticContact CE2-CZ2 3.66Å; W66-W414 AromaticContact CE3-CD2 3.93Å; W66-W414 HydrophobicContact CE3-CD2 3.93Å; W66-W414 AromaticContact CE3-CE2 3.76Å; W66-W414 AromaticContact CE3-CE3 3.79Å; W66-W414 HydrophobicContact CE3-CE3 3.79Å; W66-W414 AromaticContact CE3-CH2 3.31Å; W66-W414 HydrophobicContact CE3-CH2 3.31Å; W66-W414 AromaticContact CE3-CZ2 3.46Å; W66-W414 HydrophobicContact CE3-CZ2 3.46Å; W66-W414 VanDerWaalsContact CE3-CZ2 3.46Å; W66-W414 AromaticContact CE3-CZ3 3.5Å; W66-W414 HydrophobicContact CE3-CZ3 3.5Å; W66-W414 HydrophobicContact CG-CD2 4.41Å; W66-W414 AromaticContact CG-CE2 3.6Å; W66-W414 HydrophobicContact CG-CH2 4.32Å; W66-W414 AromaticContact CG-CZ2 3.54Å; W66-W414 HydrophobicContact CG-CZ2 3.54Å; W66-W414 AromaticContact CG-NE1 3.76Å; W66-W414 AromaticContact CH2-CH2 3.69Å; W66-W414 HydrophobicContact CH2-CH2 3.69Å; W66-W414 HydrophobicContact CH2-CZ2 4.35Å; W66-W414 HydrophobicContact CH2-CZ3 4.16Å; W66-W414 AromaticContact CZ2-CH2 3.91Å; W66-W414 HydrophobicContact CZ2-CH2 3.91Å; W66-W414 HydrophobicContact CZ2-CZ2 4.2Å; W66-W414 HydrophobicContact CZ3-CE3 4.15Å; W66-W414 AromaticContact CZ3-CH2 3.38Å; W66-W414 HydrophobicContact CZ3-CH2 3.38Å; W66-W414 HydrophobicContact CZ3-CZ2 4.01Å; W66-W414 AromaticContact CZ3-CZ3 3.47Å; W66-W414 HydrophobicContact CZ3-CZ3 3.47Å; W66-W414 VanDerWaalsContact CZ3-CZ3 3.47Å; W66-W414 PolarHBondContact N-O 3.23Å; W66-W414 PolarHBondContact O-N 2.88Å; F68-W414 AromaticContact CE2-CD1 3.96Å; F68-W414 AromaticContact CZ-CD1 3.7Å; P343-W414 HydrophobicContact CB-CB 3.89Å; P343-W414 HydrophobicContact CB-CD2 3.76Å; P343-W414 HydrophobicContact CB-CE3 3.91Å; P343-W414 HydrophobicContact CB-CG 3.77Å; P343-W414 HydrophobicContact CG-CB 4.12Å; P343-W414 HydrophobicContact CG-CD2 4.05Å; P343-W414 HydrophobicContact CG-CE3 3.7Å; P343-W414 HydrophobicContact CG-CG 4.26Å; P343-W414 HydrophobicContact CG-CZ3 4.38Å; H344-W414 AromaticContact CD2-NE1 3.94Å; H344-W414 AromaticContact NE2-NE1 3.56Å; L386-W414 CarbonylContact O-C 3.57Å; L386-W414 VanDerWaalsContact O-CA 3.23Å; L386-W414 WeakPolarHBondContact O-CA 3.33Å; L386-W414 WeakPolarHBondContact O-CB 3.13Å; Q387-W414 HydrophobicContact CB-CB 3.85Å; Q387-W414 HydrophobicContact CG-CB 4.09Å; W414-N416 HydrophobicContact CZ3-CB 4.05Å
415L98.7Very high95.7Very high8 Ų838.6 Ų38.64%0.04222%0.215CC..EExtended strand (participates in β ladder)trans-132.9149.1-177.467.190.7000111.6R63 Q64 F65 F200 R385 L386 E417R63-L415 HydrophobicContact CG-CB 4.4Å; R63-L415 HydrophobicContact CG-CD1 4.37Å; Q64-L415 CarbonylContact O-C 3.5Å; Q64-L415 WeakPolarHBondContact O-CA 3.46Å; Q64-L415 WeakPolarHBondContact O-CB 3.49Å; F65-L415 HydrophobicContact CD1-CB 3.69Å; F65-L415 HydrophobicContact CE1-CB 3.85Å; F65-L415 HydrophobicContact CE1-CD2 4.07Å; F200-L415 HydrophobicContact CE1-CD2 4.11Å; F200-L415 HydrophobicContact CZ-CD2 3.68Å; R385-L415 VanDerWaalsContact CA-O 3.28Å; R385-L415 WeakPolarHBondContact CA-O 3.46Å; L386-L415 HydrophobicContact CB-CD1 4.39Å; L386-L415 HydrophobicContact CB-CG 4.27Å; L386-L415 PolarHBondContact N-O 2.91Å; L386-L415 VanDerWaalsContact N-O 3.12Å; L386-L415 PolarHBondContact O-N 3.17Å; L415-E417 HydrophobicContact CD1-CB 4.33Å
416N98.7Very high95.8Very high18 Ų1830.5 Ų30.510%0.09618%0.177CC..EExtended strand (participates in β ladder)trans-117.8106.6165.9177.923.9000108.5R63 Q64 W66 R385 W414R63-N416 WeakPolarHBondContact CA-O 3.2Å; Q64-N416 HydrophobicContact CB-CB 4.47Å; Q64-N416 PolarHBondContact N-O 3.12Å; Q64-N416 PolarHBondContact O-N 3.05Å; Q64-N416 PolarHBondContact OE1-ND2 3.28Å; W66-N416 HydrophobicContact CH2-CB 4.29Å; W66-N416 HydrophobicContact CZ3-CB 3.81Å; R385-N416 HydrophobicContact CG-CB 4.42Å; W414-N416 HydrophobicContact CZ3-CB 4.05Å
417E98.2Very high95.7Very high4 Ų430.5 Ų30.52%0.01918%0.179CC..EExtended strand (participates in β ladder)trans-92.7113.4165.7-176.3173.1127.100109V61 Y62 R63 R96 F382 K384 L415V61-E417 HydrophobicContact CG1-CG 3.68Å; Y62-E417 CarbonylContact O-C 3.56Å; Y62-E417 VanDerWaalsContact O-CA 3.29Å; Y62-E417 WeakPolarHBondContact O-CA 3.35Å; R63-E417 HydrophobicContact CG-CB 4.33Å; R63-E417 IonicContact CZ-OE2 3.31Å; R63-E417 IonicContact NE-OE2 3.45Å; R63-E417 PolarHBondContact NE-OE2 3.39Å; R63-E417 IonicContact NH2-OE2 2.73Å; R63-E417 PolarHBondContact NH2-OE2 2.86Å; R96-E417 IonicContact CZ-OE1 3.25Å; R96-E417 IonicContact NE-OE1 2.64Å; R96-E417 PolarHBondContact NE-OE1 3.04Å; R96-E417 IonicContact NH2-OE1 2.75Å; R96-E417 PolarHBondContact NH2-OE1 2.84Å; F382-E417 WeakPolarHBondContact CD2-O 3.47Å; F382-E417 HydrophobicContact CE2-CG 4.07Å; F382-E417 WeakPolarHBondContact CE2-O 3.3Å; F382-E417 HydrophobicContact CZ-CG 4.37Å; K384-E417 HydrophobicContact CB-CB 4.27Å; K384-E417 PolarHBondContact N-O 3Å; K384-E417 PolarHBondContact O-N 2.77Å; L415-E417 HydrophobicContact CD1-CB 4.33Å
418S97.7Very high95.4Very high26 Ų2630.7 Ų30.718%0.18218%0.176CC..EExtended strand (participates in β ladder)trans-136.9153.4-174.159.70000112.3Y62 F382Y62-S418 PolarHBondContact N-O 3.06Å; Y62-S418 PolarHBondContact O-N 3.06Å; F382-S418 WeakPolarHBondContact O-CA 3.45Å; F382-S418 VanDerWaalsContact O-CB 3.25Å; F382-S418 WeakPolarHBondContact O-CB 3.43Å
419A96.5Very high95Very high6 Ų630.1 Ų30.15%0.0517%0.174CC..EExtended strand (participates in β ladder)trans-148.8151.4171.700000109.7V61 Q381 F382V61-A419 HydrophobicContact CB-CB 4.41Å; V61-A419 HydrophobicContact CG1-CB 4.49Å; V61-A419 HydrophobicContact CG2-CB 3.99Å; Q381-A419 VanDerWaalsContact CA-O 3.27Å; Q381-A419 WeakPolarHBondContact CA-O 3.27Å; F382-A419 HydrophobicContact CD1-CB 4.03Å; F382-A419 HydrophobicContact CE1-CB 3.45Å; F382-A419 VanDerWaalsContact CE1-CB 3.45Å; F382-A419 HydrophobicContact CZ-CB 4.08Å; F382-A419 PolarHBondContact N-O 3.34Å; F382-A419 PolarHBondContact O-N 3.07Å
420V96.6Very high94.7Very high61 Ų6133 Ų3337%0.3718%0.184SC..EExtended strand (participates in β ladder)trans-132.4137.2170.9-174.20000107.2S59 V284 Q381 G422S59-V420 WeakPolarHBondContact CB-O 3.26Å; V284-V420 HydrophobicContact CG1-CG1 3.89Å; Q381-V420 HydrophobicContact CG-CG2 4Å; V420-G422 PolarHBondContact O-N 3.42Å
421I94Very high94.2Very high10 Ų1036.8 Ų36.85%0.05121%0.205CC..  trans-50.4127.8174.8-173170.4000111.9S59 V284 K285 I287 L380 K425 A426 F429S59-I421 VanDerWaalsContact OG-CA 3.25Å; S59-I421 WeakPolarHBondContact OG-CA 3.4Å; S59-I421 PolarHBondContact OG-N 2.96Å; V284-I421 HydrophobicContact CG1-CG2 4.35Å; K285-I421 HydrophobicContact CD-CG2 4.3Å; K285-I421 VanDerWaalsContact CD-O 3.24Å; K285-I421 WeakPolarHBondContact CD-O 3.38Å; K285-I421 WeakPolarHBondContact CE-O 3.43Å; K285-I421 PolarHBondContact NZ-O 3.46Å; I287-I421 HydrophobicContact CD1-CD1 4.37Å; L380-I421 HydrophobicContact CB-CB 4.34Å; L380-I421 HydrophobicContact CB-CG2 4.21Å; L380-I421 HydrophobicContact CD1-CD1 4.16Å; L380-I421 HydrophobicContact CD2-CD1 4.21Å; L380-I421 PolarHBondContact O-N 3.48Å; I421-K425 HydrophobicContact CD1-CB 4.25Å; I421-K425 HydrophobicContact CG1-CB 3.92Å; I421-A426 HydrophobicContact CD1-CB 4.14Å; I421-A426 HydrophobicContact CG1-CB 4.15Å; I421-A426 HydrophobicContact CG2-CB 4.18Å; I421-F429 HydrophobicContact CD1-CB 4.38Å
422G92.3Very high93.4Very high28 Ų2841 Ų4129%0.28922%0.223SC..  trans-66.2153.9177.100000112.3V420 A424 K425 A426V420-G422 PolarHBondContact O-N 3.42Å; G422-A424 PolarHBondContact O-N 2.89Å; G422-K425 PolarHBondContact O-N 3.25Å; G422-K425 VanDerWaalsContact O-N 3.16Å; G422-A426 WeakPolarHBondContact O-CB 3.31Å; G422-A426 PolarHBondContact O-N 3.08Å
423D92.6Very high92.7Very high112 Ų11241.3 Ų41.360%0.59923%0.225SC*.Hα-helixtrans-60.4-45.2-172.1-62.4-57.8000113.4K285 K425 A426 E427K285-D423 VanDerWaalsContact CD-OD1 3.27Å; K285-D423 WeakPolarHBondContact CD-OD1 3.32Å; K285-D423 WeakPolarHBondContact CE-OD1 3.4Å; K285-D423 IonicContact NZ-OD1 3.49Å; K285-D423 PolarHBondContact NZ-OD1 3.06Å; K285-D423 IonicContact NZ-OD2 3.09Å; K285-D423 PolarHBondContact NZ-OD2 3.25Å; D423-K425 VanDerWaalsContact C-N 3.31Å; D423-K425 PolarHBondContact O-N 2.8Å; D423-A426 PolarHBondContact O-N 3.42Å; D423-E427 WeakPolarHBondContact O-CB 3.21Å; D423-E427 PolarHBondContact O-N 2.88Å
424A90.3Very high91.9Very high79 Ų7941.8 Ų41.865%0.65323%0.228SC*.Hα-helixtrans-61.2-39.6177.200000112.3G422 M428G422-A424 PolarHBondContact O-N 2.89Å; A424-M428 WeakPolarHBondContact O-CB 3.36Å; A424-M428 PolarHBondContact O-N 2.93Å
425K89Confident91.3Very high78 Ų7844.7 Ų44.734%0.33924%0.244SC..Hα-helixtrans-73-36177.1-69.5-68.2-174.4173.60111.6I421 G422 D423 M428 F429I421-K425 HydrophobicContact CD1-CB 4.25Å; I421-K425 HydrophobicContact CG1-CB 3.92Å; G422-K425 PolarHBondContact O-N 3.25Å; G422-K425 VanDerWaalsContact O-N 3.16Å; D423-K425 VanDerWaalsContact C-N 3.31Å; D423-K425 PolarHBondContact O-N 2.8Å; K425-M428 HydrophobicContact CD-SD 4.36Å; K425-M428 PolarHBondContact O-N 3.31Å; K425-F429 VanDerWaalsContact O-CB 3.27Å; K425-F429 WeakPolarHBondContact O-CB 3.44Å; K425-F429 PolarHBondContact O-N 2.98Å
426A92.6Very high90.4Very high0 Ų051.7 Ų51.70%027%0.27CS..Hα-helixtrans-64.8-42.3174.200000111.4K285 I287 I421 G422 D423 F429 R430K285-A426 HydrophobicContact CB-CB 3.84Å; K285-A426 HydrophobicContact CD-CB 3.88Å; I287-A426 HydrophobicContact CD1-CB 4.08Å; I421-A426 HydrophobicContact CD1-CB 4.14Å; I421-A426 HydrophobicContact CG1-CB 4.15Å; I421-A426 HydrophobicContact CG2-CB 4.18Å; G422-A426 WeakPolarHBondContact O-CB 3.31Å; G422-A426 PolarHBondContact O-N 3.08Å; D423-A426 PolarHBondContact O-N 3.42Å; A426-F429 PolarHBondContact O-N 2.95Å; A426-R430 WeakPolarHBondContact O-CG 3.3Å; A426-R430 PolarHBondContact O-N 3.22Å
427E91.9Very high89.7Confident107 Ų10752.2 Ų52.250%0.527%0.273SS..Hα-helixtrans-62.9-47.7174-174.9178.7-178.600112.1D423 F429 R430 N431D423-E427 WeakPolarHBondContact O-CB 3.21Å; D423-E427 PolarHBondContact O-N 2.88Å; E427-F429 VanDerWaalsContact C-N 3.27Å; E427-F429 PolarHBondContact O-N 3.24Å; E427-R430 PolarHBondContact O-N 2.81Å; E427-N431 WeakPolarHBondContact O-CB 3.4Å; E427-N431 VanDerWaalsContact O-CG 3.31Å; E427-N431 PolarHBondContact O-N 3.4Å; E427-N431 PolarHBondContact O-ND2 2.9Å
428M87.6Confident89Confident61 Ų6157 Ų5730%0.330%0.295SS..Hα-helixtrans-56.9-42.9174.1-177.8-175.5175.400111.6A424 K425 N431 K432A424-M428 WeakPolarHBondContact O-CB 3.36Å; A424-M428 PolarHBondContact O-N 2.93Å; K425-M428 HydrophobicContact CD-SD 4.36Å; K425-M428 PolarHBondContact O-N 3.31Å; M428-N431 PolarHBondContact O-N 2.94Å; M428-K432 HydrophobicContact CE-CD 4.06Å; M428-K432 HydrophobicContact CG-CD 4.29Å; M428-K432 WeakPolarHBondContact O-CB 3.49Å; M428-K432 WeakPolarHBondContact O-CG 3.25Å; M428-K432 PolarHBondContact O-N 3.43Å
429F89.3Confident88.3Confident15 Ų1562.3 Ų62.37%0.06632%0.319CS..Hα-helixtrans-63.5-48.3177.9-172-84.5000111.6I287 E373 T376 F378 L380 I421 K425 A426 E427 N431 K432 V433I287-F429 HydrophobicContact CD1-CB 4.18Å; I287-F429 HydrophobicContact CD1-CD1 3.67Å; I287-F429 HydrophobicContact CD1-CE1 4.47Å; I287-F429 HydrophobicContact CD1-CG 4.18Å; I287-F429 HydrophobicContact CG1-CD1 4.16Å; I287-F429 HydrophobicContact CG2-CD1 4.1Å; I287-F429 HydrophobicContact CG2-CE1 3.87Å; E373-F429 HydrophobicContact CB-CZ 4.16Å; E373-F429 HydrophobicContact CG-CE1 3.75Å; E373-F429 HydrophobicContact CG-CZ 3.64Å; T376-F429 HydrophobicContact CG2-CE2 4.09Å; T376-F429 HydrophobicContact CG2-CZ 3.95Å; F378-F429 HydrophobicContact CD2-CE2 4.01Å; L380-F429 HydrophobicContact CD1-CD1 4.4Å; L380-F429 HydrophobicContact CD1-CE1 4.3Å; L380-F429 HydrophobicContact CD1-CE2 4.47Å; L380-F429 HydrophobicContact CD1-CZ 4.33Å; I421-F429 HydrophobicContact CD1-CB 4.38Å; K425-F429 VanDerWaalsContact O-CB 3.27Å; K425-F429 WeakPolarHBondContact O-CB 3.44Å; K425-F429 PolarHBondContact O-N 2.98Å; A426-F429 PolarHBondContact O-N 2.95Å; E427-F429 VanDerWaalsContact C-N 3.27Å; E427-F429 PolarHBondContact O-N 3.24Å; F429-N431 VanDerWaalsContact C-N 3.32Å; F429-N431 PolarHBondContact O-N 3.1Å; F429-K432 PolarHBondContact O-N 2.94Å; F429-V433 HydrophobicContact CD1-CB 4.38Å; F429-V433 HydrophobicContact CD2-CG2 4.35Å; F429-V433 HydrophobicContact CE1-CB 4.02Å; F429-V433 HydrophobicContact CE1-CG1 4.2Å; F429-V433 HydrophobicContact CE1-CG2 4.46Å; F429-V433 HydrophobicContact CE2-CG2 4.09Å; F429-V433 HydrophobicContact CZ-CB 4.09Å; F429-V433 HydrophobicContact CZ-CG1 4.07Å; F429-V433 HydrophobicContact CZ-CG2 4.15Å; F429-V433 WeakPolarHBondContact O-CB 3.4Å; F429-V433 PolarHBondContact O-N 3.11Å
430R90.4Very high87.8Confident69 Ų6964.3 Ų64.326%0.2633%0.329SS..Iπ-helixtrans-57.5-46176.1-71.2-171.6-51.2-89.6-2.4111.2K285 I287 A426 E427 K432 T434 N435K285-R430 PolarHBondContact O-NH1 2.81Å; I287-R430 HydrophobicContact CD1-CG 4.31Å; I287-R430 HydrophobicContact CG1-CG 3.69Å; A426-R430 WeakPolarHBondContact O-CG 3.3Å; A426-R430 PolarHBondContact O-N 3.22Å; E427-R430 PolarHBondContact O-N 2.81Å; R430-K432 PolarHBondContact O-N 2.9Å; R430-T434 PolarHBondContact O-N 2.88Å; R430-N435 VanDerWaalsContact O-CB 3.27Å; R430-N435 WeakPolarHBondContact O-CB 3.33Å; R430-N435 VanDerWaalsContact O-CG 3.24Å; R430-N435 PolarHBondContact O-N 3.16Å
431N86.8Confident87.2Confident82 Ų8263.4 Ų63.444%0.43933%0.325SS..Iπ-helixtrans-66.4-38-178.4-71.3-21.1000113.1E427 M428 F429 N435E427-N431 WeakPolarHBondContact O-CB 3.4Å; E427-N431 VanDerWaalsContact O-CG 3.31Å; E427-N431 PolarHBondContact O-N 3.4Å; E427-N431 PolarHBondContact O-ND2 2.9Å; M428-N431 PolarHBondContact O-N 2.94Å; F429-N431 VanDerWaalsContact C-N 3.32Å; F429-N431 PolarHBondContact O-N 3.1Å; N431-N435 PolarHBondContact OD1-ND2 2.75Å; N431-N435 VanDerWaalsContact OD1-ND2 3.1Å
432K82.5Confident86.9Confident88 Ų8866.8 Ų66.838%0.38335%0.346SS..Iπ-helixtrans-84.5-31.4-177.8-71.9-167.6176.3-169.20113.8I49 M428 F429 R430 R436I49-K432 HydrophobicContact CD1-CB 4.49Å; I49-K432 HydrophobicContact CD1-CD 3.75Å; M428-K432 HydrophobicContact CE-CD 4.06Å; M428-K432 HydrophobicContact CG-CD 4.29Å; M428-K432 WeakPolarHBondContact O-CB 3.49Å; M428-K432 WeakPolarHBondContact O-CG 3.25Å; M428-K432 PolarHBondContact O-N 3.43Å; F429-K432 PolarHBondContact O-N 2.94Å; R430-K432 PolarHBondContact O-N 2.9Å; K432-R436 VanDerWaalsContact O-CD 3.28Å; K432-R436 WeakPolarHBondContact O-CD 3.43Å
433V84.2Confident86.7Confident11 Ų1169.1 Ų69.17%0.06735%0.351CS..Iπ-helixtrans-117.8-72.1-171.6-174.80000110.3I38 T376 F429 N435 R436 V437I38-V433 HydrophobicContact CD1-CG1 4.1Å; T376-V433 HydrophobicContact CG2-CG1 4.03Å; T376-V433 HydrophobicContact CG2-CG2 4.36Å; F429-V433 HydrophobicContact CD1-CB 4.38Å; F429-V433 HydrophobicContact CD2-CG2 4.35Å; F429-V433 HydrophobicContact CE1-CB 4.02Å; F429-V433 HydrophobicContact CE1-CG1 4.2Å; F429-V433 HydrophobicContact CE1-CG2 4.46Å; F429-V433 HydrophobicContact CE2-CG2 4.09Å; F429-V433 HydrophobicContact CZ-CB 4.09Å; F429-V433 HydrophobicContact CZ-CG1 4.07Å; F429-V433 HydrophobicContact CZ-CG2 4.15Å; F429-V433 WeakPolarHBondContact O-CB 3.4Å; F429-V433 PolarHBondContact O-N 3.11Å; V433-N435 PolarHBondContact O-N 3.25Å; V433-R436 PolarHBondContact O-N 3.02Å; V433-V437 WeakPolarHBondContact O-CG2 3.45Å; V433-V437 PolarHBondContact O-N 3.05Å
434T82.1Confident86.5Confident11 Ų1164.5 Ų64.57%0.06733%0.326CS..Iπ-helixtrans-57.9-49.4-168.9-47.40000113.2R430 R436 V437 Q438R430-T434 PolarHBondContact O-N 2.88Å; T434-R436 VanDerWaalsContact C-N 3.34Å; T434-R436 PolarHBondContact O-N 2.74Å; T434-V437 PolarHBondContact O-N 3.35Å; T434-Q438 HydrophobicContact CG2-CG 4.48Å; T434-Q438 WeakPolarHBondContact O-CB 3.47Å; T434-Q438 WeakPolarHBondContact O-CG 3.15Å; T434-Q438 PolarHBondContact O-N 2.67Å
435N84.4Confident86.4Confident65 Ų6565.9 Ų65.935%0.34832%0.321SS..Hα-helixtrans-67.7-34.2-176.1-68.2-5.9000111.8R430 N431 V433 M439R430-N435 VanDerWaalsContact O-CB 3.27Å; R430-N435 WeakPolarHBondContact O-CB 3.33Å; R430-N435 VanDerWaalsContact O-CG 3.24Å; R430-N435 PolarHBondContact O-N 3.16Å; N431-N435 PolarHBondContact OD1-ND2 2.75Å; N431-N435 VanDerWaalsContact OD1-ND2 3.1Å; V433-N435 PolarHBondContact O-N 3.25Å; N435-M439 WeakPolarHBondContact O-CB 3.46Å; N435-M439 PolarHBondContact O-N 3.17Å
436R81.8Confident86.6Confident155 Ų15566.1 Ų66.159%0.58533%0.328SS*.Hα-helixtrans-67.2-44.5177.3-68.1-169.3179.7169.6-7.6111.3K432 V433 T434 L440K432-R436 VanDerWaalsContact O-CD 3.28Å; K432-R436 WeakPolarHBondContact O-CD 3.43Å; V433-R436 PolarHBondContact O-N 3.02Å; T434-R436 VanDerWaalsContact C-N 3.34Å; T434-R436 PolarHBondContact O-N 2.74Å; R436-L440 WeakPolarHBondContact O-CG 3.47Å; R436-L440 PolarHBondContact O-N 2.94Å
437V82.9Confident86.6Confident29 Ų2967.4 Ų67.418%0.17634%0.335CS..Hα-helixtrans-64.7-45.5177.31770000110.6I34 I375 V433 T434 L440 S441I34-V437 HydrophobicContact CD1-CB 4.5Å; I34-V437 HydrophobicContact CD1-CG1 4.35Å; I34-V437 HydrophobicContact CD1-CG2 4.27Å; I34-V437 HydrophobicContact CG2-CG2 3.9Å; I375-V437 HydrophobicContact CD1-CG1 4.14Å; I375-V437 HydrophobicContact CD1-CG2 4.17Å; V433-V437 WeakPolarHBondContact O-CG2 3.45Å; V433-V437 PolarHBondContact O-N 3.05Å; T434-V437 PolarHBondContact O-N 3.35Å; V437-L440 PolarHBondContact O-N 3.49Å; V437-S441 PolarHBondContact O-N 2.86Å; V437-S441 VanDerWaalsContact O-N 3.07Å; V437-S441 PolarHBondContact O-OG 3.27Å
438Q82.8Confident86.7Confident103 Ų10365 Ų6548%0.48133%0.325SS..Hα-helixtrans-65.2-43177.7-74.4-179.8-5.100112.5T434 L440 S441 V442T434-Q438 HydrophobicContact CG2-CG 4.48Å; T434-Q438 WeakPolarHBondContact O-CB 3.47Å; T434-Q438 WeakPolarHBondContact O-CG 3.15Å; T434-Q438 PolarHBondContact O-N 2.67Å; Q438-L440 VanDerWaalsContact C-N 3.34Å; Q438-L440 PolarHBondContact O-N 2.93Å; Q438-S441 PolarHBondContact O-N 3.41Å; Q438-V442 WeakPolarHBondContact O-CB 3.37Å; Q438-V442 VanDerWaalsContact O-CG2 3.28Å; Q438-V442 WeakPolarHBondContact O-CG2 3.14Å; Q438-V442 PolarHBondContact O-N 3.18Å
439M84.8Confident87Confident139 Ų13967.2 Ų67.269%0.68534%0.337SS*.Hα-helixtrans-60-43.5178.8-179.1-175.7174.400111.6N435 V442 L443N435-M439 WeakPolarHBondContact O-CB 3.46Å; N435-M439 PolarHBondContact O-N 3.17Å; M439-V442 PolarHBondContact O-N 3.45Å; M439-L443 VanDerWaalsContact O-CB 3.27Å; M439-L443 WeakPolarHBondContact O-CB 3.31Å; M439-L443 PolarHBondContact O-N 2.86Å
440L84.1Confident87.3Confident48 Ų4868.5 Ų68.525%0.25135%0.351SS..Hα-helixtrans-64-44.5175.9-74.5169.6000111.5I34 R436 V437 Q438 V442 L443 Q444I34-L440 HydrophobicContact CD1-CB 4.37Å; I34-L440 HydrophobicContact CD1-CD1 3.63Å; I34-L440 HydrophobicContact CG1-CD1 3.64Å; R436-L440 WeakPolarHBondContact O-CG 3.47Å; R436-L440 PolarHBondContact O-N 2.94Å; V437-L440 PolarHBondContact O-N 3.49Å; Q438-L440 VanDerWaalsContact C-N 3.34Å; Q438-L440 PolarHBondContact O-N 2.93Å; L440-V442 PolarHBondContact O-N 2.99Å; L440-L443 PolarHBondContact O-N 2.73Å; L440-Q444 WeakPolarHBondContact O-CB 3.3Å; L440-Q444 WeakPolarHBondContact O-CG 3.34Å; L440-Q444 PolarHBondContact O-N 2.93Å
441S84.6Confident87.4Confident42 Ų4265.2 Ų65.229%0.29434%0.338SS..Hα-helixtrans-61.9-42.6177.4-56.50000112.3V437 Q438 M445V437-S441 PolarHBondContact O-N 2.86Å; V437-S441 VanDerWaalsContact O-N 3.07Å; V437-S441 PolarHBondContact O-OG 3.27Å; Q438-S441 PolarHBondContact O-N 3.41Å; S441-M445 WeakPolarHBondContact O-CE 3.48Å; S441-M445 PolarHBondContact O-N 3.33Å
442V87.4Confident87.8Confident81 Ų8163.6 Ų63.649%0.49133%0.333SS..Hα-helixtrans-66.8-44.6176.8170.70000110.7Q438 M439 L440 Q444 M445 V446Q438-V442 WeakPolarHBondContact O-CB 3.37Å; Q438-V442 VanDerWaalsContact O-CG2 3.28Å; Q438-V442 WeakPolarHBondContact O-CG2 3.14Å; Q438-V442 PolarHBondContact O-N 3.18Å; M439-V442 PolarHBondContact O-N 3.45Å; L440-V442 PolarHBondContact O-N 2.99Å; V442-Q444 VanDerWaalsContact C-N 3.34Å; V442-Q444 PolarHBondContact O-N 2.81Å; V442-M445 PolarHBondContact O-N 2.91Å; V442-V446 HydrophobicContact CG1-CG2 4.18Å; V442-V446 WeakPolarHBondContact O-CB 3.32Å; V442-V446 VanDerWaalsContact O-CG2 3.28Å; V442-V446 WeakPolarHBondContact O-CG2 3.43Å; V442-V446 PolarHBondContact O-N 3.38Å
443L88.4Confident88.4Confident76 Ų7663.7 Ų63.740%0.39834%0.341SS..Hα-helixtrans-59.9-44.7177179.362.5000111.3L26 M439 L440 V446 L447L26-L443 HydrophobicContact CD2-CD2 4.02Å; L26-L443 HydrophobicContact CD2-CG 4.2Å; M439-L443 VanDerWaalsContact O-CB 3.27Å; M439-L443 WeakPolarHBondContact O-CB 3.31Å; M439-L443 PolarHBondContact O-N 2.86Å; L440-L443 PolarHBondContact O-N 2.73Å; L443-V446 PolarHBondContact O-N 2.77Å; L443-L447 HydrophobicContact CD1-CD1 4.09Å; L443-L447 HydrophobicContact CD1-CG 4.21Å; L443-L447 HydrophobicContact CG-CD1 3.99Å; L443-L447 WeakPolarHBondContact O-CB 2.86Å; L443-L447 VanDerWaalsContact O-CG 3.25Å; L443-L447 WeakPolarHBondContact O-CG 3.46Å; L443-L447 PolarHBondContact O-N 3.02Å
444Q88.6Confident88.9Confident15 Ų1566.3 Ų66.37%0.0735%0.354CS..Hα-helixtrans-57.7-51.1174.5-71.4162.10.700111L26 I27 L440 V442 V446 L447 I448L26-Q444 HydrophobicContact CB-CG 4.12Å; L26-Q444 HydrophobicContact CD2-CG 4Å; L26-Q444 HydrophobicContact CG-CG 4.01Å; L26-Q444 PolarHBondContact O-NE2 2.88Å; I27-Q444 HydrophobicContact CG1-CB 4.25Å; I27-Q444 HydrophobicContact CG1-CG 4.14Å; L440-Q444 WeakPolarHBondContact O-CB 3.3Å; L440-Q444 WeakPolarHBondContact O-CG 3.34Å; L440-Q444 PolarHBondContact O-N 2.93Å; V442-Q444 VanDerWaalsContact C-N 3.34Å; V442-Q444 PolarHBondContact O-N 2.81Å; Q444-V446 PolarHBondContact O-N 2.82Å; Q444-L447 PolarHBondContact O-N 2.92Å; Q444-I448 VanDerWaalsContact O-CG1 3.31Å; Q444-I448 WeakPolarHBondContact O-CG1 3.45Å; Q444-I448 PolarHBondContact O-N 2.62Å
445M89Confident89.5Confident108 Ų10869.6 Ų69.653%0.53237%0.368SS..Hα-helixtrans-60-44.9178.3-80.2-173.5-83.600112.4S441 V442 I448 I449S441-M445 WeakPolarHBondContact O-CE 3.48Å; S441-M445 PolarHBondContact O-N 3.33Å; V442-M445 PolarHBondContact O-N 2.91Å; M445-I448 PolarHBondContact O-N 3.48Å; M445-I449 WeakPolarHBondContact O-CB 3.49Å; M445-I449 VanDerWaalsContact O-CG1 3.24Å; M445-I449 WeakPolarHBondContact O-CG1 3.49Å; M445-I449 PolarHBondContact O-N 3.09Å
446V92.8Very high90Very high83 Ų8371.5 Ų71.550%0.50338%0.378SS..Hα-helixtrans-62.9-45.4179.3169.20000111V442 L443 Q444 I448 I449 A450V442-V446 HydrophobicContact CG1-CG2 4.18Å; V442-V446 WeakPolarHBondContact O-CB 3.32Å; V442-V446 VanDerWaalsContact O-CG2 3.28Å; V442-V446 WeakPolarHBondContact O-CG2 3.43Å; V442-V446 PolarHBondContact O-N 3.38Å; L443-V446 PolarHBondContact O-N 2.77Å; Q444-V446 PolarHBondContact O-N 2.82Å; V446-I448 VanDerWaalsContact C-N 3.34Å; V446-I448 PolarHBondContact O-N 3.45Å; V446-I449 PolarHBondContact O-N 3.4Å; V446-A450 WeakPolarHBondContact O-CB 3.45Å; V446-A450 PolarHBondContact O-N 3.32Å
447L92.8Very high90.5Very high28 Ų2866.5 Ų66.515%0.14737%0.369CS..Hα-helixtrans-61.6-42.2178.5-73.5169000112L19 F22 L26 L443 Q444 G451L19-L447 HydrophobicContact CD2-CD2 4.08Å; F22-L447 HydrophobicContact CD1-CD1 3.92Å; F22-L447 HydrophobicContact CE1-CD1 4.2Å; L26-L447 HydrophobicContact CD2-CD1 4.02Å; L443-L447 HydrophobicContact CD1-CD1 4.09Å; L443-L447 HydrophobicContact CD1-CG 4.21Å; L443-L447 HydrophobicContact CG-CD1 3.99Å; L443-L447 WeakPolarHBondContact O-CB 2.86Å; L443-L447 VanDerWaalsContact O-CG 3.25Å; L443-L447 WeakPolarHBondContact O-CG 3.46Å; L443-L447 PolarHBondContact O-N 3.02Å; Q444-L447 PolarHBondContact O-N 2.92Å; L447-G451 WeakPolarHBondContact O-CA 3.39Å; L447-G451 PolarHBondContact O-N 2.79Å
448I93.4Very high91Very high55 Ų5568.4 Ų68.428%0.28238%0.375SS..Hα-helixtrans-67.7-49.9178.8-67.5169000110.9I27 Q444 M445 V446 S452I27-I448 HydrophobicContact CD1-CD1 3.73Å; Q444-I448 VanDerWaalsContact O-CG1 3.31Å; Q444-I448 WeakPolarHBondContact O-CG1 3.45Å; Q444-I448 PolarHBondContact O-N 2.62Å; M445-I448 PolarHBondContact O-N 3.48Å; V446-I448 VanDerWaalsContact C-N 3.34Å; V446-I448 PolarHBondContact O-N 3.45Å; I448-S452 WeakPolarHBondContact O-CB 3.48Å; I448-S452 PolarHBondContact O-N 2.99Å; I448-S452 PolarHBondContact O-OG 2.69Å
449I94.2Very high91.4Very high108 Ų10865.7 Ų65.755%0.55436%0.363SS*.Hα-helixtrans-66.1-52.4-177.4-66.6167.8000110.2M445 V446 G451 S452 V453M445-I449 WeakPolarHBondContact O-CB 3.49Å; M445-I449 VanDerWaalsContact O-CG1 3.24Å; M445-I449 WeakPolarHBondContact O-CG1 3.49Å; M445-I449 PolarHBondContact O-N 3.09Å; V446-I449 PolarHBondContact O-N 3.4Å; I449-G451 PolarHBondContact O-N 2.89Å; I449-S452 PolarHBondContact O-N 2.88Å; I449-V453 HydrophobicContact CG2-CG2 4.44Å; I449-V453 WeakPolarHBondContact O-CB 3.29Å; I449-V453 VanDerWaalsContact O-CG2 3.27Å; I449-V453 WeakPolarHBondContact O-CG2 3.45Å; I449-V453 PolarHBondContact O-N 3Å
450A94.5Very high91.7Very high43 Ų4362.9 Ų62.936%0.35535%0.354SS..Hα-helixtrans-63.9-42.7-178.800000111.6V446 V453 L454V446-A450 WeakPolarHBondContact O-CB 3.45Å; V446-A450 PolarHBondContact O-N 3.32Å; A450-V453 PolarHBondContact O-N 3.12Å; A450-L454 WeakPolarHBondContact O-CB 3.15Å; A450-L454 VanDerWaalsContact O-CG 3.28Å; A450-L454 WeakPolarHBondContact O-CG 3.42Å; A450-L454 PolarHBondContact O-N 2.85Å
451G94.5Very high92Very high0 Ų063 Ų630%036%0.359CS..Hα-helixtrans-60.6-45.217600000112.3G16 L447 I449 L454 F455G16-G451 CarbonylContact C-O 3.33Å; G16-G451 WeakPolarHBondContact CA-O 3.41Å; G16-G451 CarbonylContact O-C 3.53Å; G16-G451 VanDerWaalsContact O-CA 3.25Å; G16-G451 WeakPolarHBondContact O-CA 3.39Å; G16-G451 VanDerWaalsContact O-O 3.14Å; L447-G451 WeakPolarHBondContact O-CA 3.39Å; L447-G451 PolarHBondContact O-N 2.79Å; I449-G451 PolarHBondContact O-N 2.89Å; G451-L454 PolarHBondContact O-N 2.84Å; G451-F455 WeakPolarHBondContact O-CB 3.46Å; G451-F455 PolarHBondContact O-N 3.01Å
452S93.8Very high92.2Very high47 Ų4763 Ų6333%0.32935%0.352SS..Hα-helixtrans-65.9-42.8178.7-58.50000112.3I448 I449 F455 L456I448-S452 WeakPolarHBondContact O-CB 3.48Å; I448-S452 PolarHBondContact O-N 2.99Å; I448-S452 PolarHBondContact O-OG 2.69Å; I449-S452 PolarHBondContact O-N 2.88Å; S452-F455 PolarHBondContact O-N 3.4Å; S452-L456 WeakPolarHBondContact O-CB 3.47Å; S452-L456 VanDerWaalsContact O-CG 3.32Å; S452-L456 WeakPolarHBondContact O-CG 3.36Å; S452-L456 PolarHBondContact O-N 2.99Å
453V95.8Very high92.1Very high90 Ų9064.8 Ų64.855%0.54535%0.354SS..Hα-helixtrans-63.9-45.6177.1170.60000110.9I449 A450 L456 A457I449-V453 HydrophobicContact CG2-CG2 4.44Å; I449-V453 WeakPolarHBondContact O-CB 3.29Å; I449-V453 VanDerWaalsContact O-CG2 3.27Å; I449-V453 WeakPolarHBondContact O-CG2 3.45Å; I449-V453 PolarHBondContact O-N 3Å; A450-V453 PolarHBondContact O-N 3.12Å; V453-L456 PolarHBondContact O-N 3.39Å; V453-A457 VanDerWaalsContact O-CB 3.27Å; V453-A457 WeakPolarHBondContact O-CB 3.49Å; V453-A457 PolarHBondContact O-N 3.48Å
454L94.3Very high92.1Very high67 Ų6765.2 Ų65.235%0.35136%0.356SS..Hα-helixtrans-60.4-48.1176.1-76.1166.9000111L19 A450 G451 L456 A457 F458L19-L454 HydrophobicContact CD1-CD1 4.09Å; A450-L454 WeakPolarHBondContact O-CB 3.15Å; A450-L454 VanDerWaalsContact O-CG 3.28Å; A450-L454 WeakPolarHBondContact O-CG 3.42Å; A450-L454 PolarHBondContact O-N 2.85Å; G451-L454 PolarHBondContact O-N 2.84Å; L454-L456 PolarHBondContact O-N 3.16Å; L454-A457 PolarHBondContact O-N 3.07Å; L454-F458 HydrophobicContact CD2-CD2 4.36Å; L454-F458 HydrophobicContact CD2-CE2 3.89Å; L454-F458 WeakPolarHBondContact O-CB 3.24Å; L454-F458 VanDerWaalsContact O-CD2 3.26Å; L454-F458 WeakPolarHBondContact O-CD2 3.45Å; L454-F458 PolarHBondContact O-N 2.75Å
455F94.5Very high91.7Very high79 Ų7965.8 Ų65.835%0.34636%0.361SS..Hα-helixtrans-55.2-52177.8175.7-103.5000111.5A13 A17 G451 S452 M459A13-F455 HydrophobicContact CB-CD2 4.23Å; A13-F455 WeakPolarHBondContact O-CD2 3.22Å; A17-F455 HydrophobicContact CB-CD2 3.81Å; A17-F455 HydrophobicContact CB-CE2 4.18Å; G451-F455 WeakPolarHBondContact O-CB 3.46Å; G451-F455 PolarHBondContact O-N 3.01Å; S452-F455 PolarHBondContact O-N 3.4Å; F455-M459 HydrophobicContact CD1-CG 4.49Å; F455-M459 HydrophobicContact CD2-CG 4.08Å; F455-M459 HydrophobicContact CE1-CG 4.2Å; F455-M459 HydrophobicContact CE2-CG 3.76Å; F455-M459 HydrophobicContact CE2-SD 4.29Å; F455-M459 HydrophobicContact CG-CG 4.45Å; F455-M459 HydrophobicContact CZ-CG 3.83Å; F455-M459 VanDerWaalsContact O-CB 3.28Å; F455-M459 WeakPolarHBondContact O-CB 3.46Å; F455-M459 WeakPolarHBondContact O-CG 3.38Å; F455-M459 PolarHBondContact O-N 3.37Å
456L94.4Very high91.3Very high106 Ų10666.9 Ų66.956%0.55536%0.359SS*.Hα-helixtrans-63.8-45.9-179.3-70172000112.1S452 V453 L454 F458 M459 V460S452-L456 WeakPolarHBondContact O-CB 3.47Å; S452-L456 VanDerWaalsContact O-CG 3.32Å; S452-L456 WeakPolarHBondContact O-CG 3.36Å; S452-L456 PolarHBondContact O-N 2.99Å; V453-L456 PolarHBondContact O-N 3.39Å; L454-L456 PolarHBondContact O-N 3.16Å; L456-F458 PolarHBondContact O-N 3.3Å; L456-M459 PolarHBondContact O-N 2.94Å; L456-V460 WeakPolarHBondContact O-CB 3.38Å; L456-V460 VanDerWaalsContact O-CG2 3.25Å; L456-V460 WeakPolarHBondContact O-CG2 3.47Å; L456-V460 PolarHBondContact O-N 3.09Å
457A93.6Very high90.3Very high50 Ų5067.2 Ų67.241%0.41336%0.362SS..Hα-helixtrans-61.2-45.2-178.900000112.2V453 L454 S461V453-A457 VanDerWaalsContact O-CB 3.27Å; V453-A457 WeakPolarHBondContact O-CB 3.49Å; V453-A457 PolarHBondContact O-N 3.48Å; L454-A457 PolarHBondContact O-N 3.07Å; A457-S461 VanDerWaalsContact O-CB 3.28Å; A457-S461 WeakPolarHBondContact O-CB 3.46Å; A457-S461 PolarHBondContact O-N 3.02Å; A457-S461 PolarHBondContact O-OG 3.36Å
458F93.1Very high89Confident69 Ų6973.7 Ų73.730%0.30339%0.389SS..Hα-helixtrans-71.7-37178.9-82.3-73.9000112.5L9 A13 L454 L456 S461 Y462L9-F458 HydrophobicContact CD2-CD1 3.76Å; L9-F458 HydrophobicContact CD2-CE1 4.19Å; A13-F458 HydrophobicContact CB-CB 3.99Å; L454-F458 HydrophobicContact CD2-CD2 4.36Å; L454-F458 HydrophobicContact CD2-CE2 3.89Å; L454-F458 WeakPolarHBondContact O-CB 3.24Å; L454-F458 VanDerWaalsContact O-CD2 3.26Å; L454-F458 WeakPolarHBondContact O-CD2 3.45Å; L454-F458 PolarHBondContact O-N 2.75Å; L456-F458 PolarHBondContact O-N 3.3Å; F458-S461 PolarHBondContact O-N 3.23Å; F458-Y462 VanDerWaalsContact O-CB 3.3Å; F458-Y462 WeakPolarHBondContact O-CB 3.5Å; F458-Y462 PolarHBondContact O-N 2.98Å
459M91Very high87.3Confident45 Ų4578.2 Ų78.222%0.22241%0.406CS..Hα-helixtrans-66.2-46.4175.3-75.1-62.4-64.900112.2A13 F455 L456 S461 Y462 F463A13-M459 HydrophobicContact CB-CG 3.83Å; A13-M459 HydrophobicContact CB-SD 3.74Å; F455-M459 HydrophobicContact CD1-CG 4.49Å; F455-M459 HydrophobicContact CD2-CG 4.08Å; F455-M459 HydrophobicContact CE1-CG 4.2Å; F455-M459 HydrophobicContact CE2-CG 3.76Å; F455-M459 HydrophobicContact CE2-SD 4.29Å; F455-M459 HydrophobicContact CG-CG 4.45Å; F455-M459 HydrophobicContact CZ-CG 3.83Å; F455-M459 VanDerWaalsContact O-CB 3.28Å; F455-M459 WeakPolarHBondContact O-CB 3.46Å; F455-M459 WeakPolarHBondContact O-CG 3.38Å; F455-M459 PolarHBondContact O-N 3.37Å; L456-M459 PolarHBondContact O-N 2.94Å; M459-S461 VanDerWaalsContact C-N 3.33Å; M459-S461 PolarHBondContact O-N 3.26Å; M459-Y462 WeakPolarHBondContact O-CB 3.14Å; M459-Y462 PolarHBondContact O-N 3.05Å; M459-F463 HydrophobicContact CE-CD2 4.44Å; M459-F463 HydrophobicContact CE-CE2 3.51Å; M459-F463 HydrophobicContact CE-CZ 3.92Å; M459-F463 WeakPolarHBondContact O-CD2 3.17Å; M459-F463 PolarHBondContact O-N 3.4Å
460V91.8Very high85.5Confident80 Ų8080 Ų8049%0.48542%0.416SS..Hα-helixtrans-60.1-46.1175.5170.50000110.2L456 Y462 F463 I464L456-V460 WeakPolarHBondContact O-CB 3.38Å; L456-V460 VanDerWaalsContact O-CG2 3.25Å; L456-V460 WeakPolarHBondContact O-CG2 3.47Å; L456-V460 PolarHBondContact O-N 3.09Å; V460-Y462 VanDerWaalsContact C-N 3.31Å; V460-Y462 PolarHBondContact O-N 3.44Å; V460-F463 PolarHBondContact O-N 3.45Å; V460-I464 HydrophobicContact CG1-CD1 3.63Å; V460-I464 HydrophobicContact CG1-CG1 4.35Å; V460-I464 VanDerWaalsContact O-CG1 3.29Å; V460-I464 WeakPolarHBondContact O-CG1 3.37Å; V460-I464 PolarHBondContact O-N 3.41Å
461S88.8Confident83.1Confident52 Ų5289.5 Ų89.536%0.36445%0.45SS..Hα-helixtrans-61-39177-62.20000112.5A457 F458 M459 C465A457-S461 VanDerWaalsContact O-CB 3.28Å; A457-S461 WeakPolarHBondContact O-CB 3.46Å; A457-S461 PolarHBondContact O-N 3.02Å; A457-S461 PolarHBondContact O-OG 3.36Å; F458-S461 PolarHBondContact O-N 3.23Å; M459-S461 VanDerWaalsContact C-N 3.33Å; M459-S461 PolarHBondContact O-N 3.26Å; S461-C465 VanDerWaalsContact O-CB 3.29Å; S461-C465 WeakPolarHBondContact O-CB 3.33Å; S461-C465 PolarHBondContact O-N 3.47Å; S461-C465 PolarHBondContact O-SG 2.97Å
462Y89Confident82.5Confident40 Ų4094 Ų9416%0.15747%0.472CS..Hα-helixtrans-62.3-48.5174.8176.5-94000111.7N6 L9 L10 F458 M459 V460 C465 R466N6-Y462 HydrophobicContact CB-CE2 4.14Å; L9-Y462 HydrophobicContact CB-CD2 4.25Å; L10-Y462 HydrophobicContact CD1-CE2 4.47Å; F458-Y462 VanDerWaalsContact O-CB 3.3Å; F458-Y462 WeakPolarHBondContact O-CB 3.5Å; F458-Y462 PolarHBondContact O-N 2.98Å; M459-Y462 WeakPolarHBondContact O-CB 3.14Å; M459-Y462 PolarHBondContact O-N 3.05Å; V460-Y462 VanDerWaalsContact C-N 3.31Å; V460-Y462 PolarHBondContact O-N 3.44Å; Y462-C465 PolarHBondContact O-N 2.83Å; Y462-R466 WeakPolarHBondContact O-CB 3.24Å; Y462-R466 PolarHBondContact O-N 3.09Å
463F87Confident81.9Confident119 Ų11996.5 Ų96.552%0.52248%0.48SS..Hα-helixtrans-63.9-42.5178.7-75.4-63.9000112.6M459 V460 R466 T467M459-F463 HydrophobicContact CE-CD2 4.44Å; M459-F463 HydrophobicContact CE-CE2 3.51Å; M459-F463 HydrophobicContact CE-CZ 3.92Å; M459-F463 WeakPolarHBondContact O-CD2 3.17Å; M459-F463 PolarHBondContact O-N 3.4Å; V460-F463 PolarHBondContact O-N 3.45Å; F463-R466 PolarHBondContact O-N 3.09Å; F463-T467 PolarHBondContact O-N 3Å; F463-T467 PolarHBondContact O-OG1 3.07Å
464I86.8Confident81.2Confident86 Ų8696.8 Ų96.844%0.44148%0.476SS..Hα-helixtrans-62.9-44.1176.5-66.6169.3000110.9V460 R466 T467 K468V460-I464 HydrophobicContact CG1-CD1 3.63Å; V460-I464 HydrophobicContact CG1-CG1 4.35Å; V460-I464 VanDerWaalsContact O-CG1 3.29Å; V460-I464 WeakPolarHBondContact O-CG1 3.37Å; V460-I464 PolarHBondContact O-N 3.41Å; I464-R466 VanDerWaalsContact C-N 3.29Å; I464-R466 PolarHBondContact O-N 3.14Å; I464-T467 WeakPolarHBondContact CA-OG1 3.23Å; I464-T467 PolarHBondContact O-OG1 3.2Å; I464-T467 VanDerWaalsContact O-OG1 3.11Å; I464-K468 PolarHBondContact O-N 3.5Å; I464-K468 VanDerWaalsContact O-N 3.13Å
465C81.3Confident80.4Confident26 Ų2698.6 Ų98.618%0.17648%0.483CS..Hα-helixtrans-66.3-31.9178.8-76.60000112.9L9 S461 Y462L9-C465 HydrophobicContact CD1-CB 4.17Å; S461-C465 VanDerWaalsContact O-CB 3.29Å; S461-C465 WeakPolarHBondContact O-CB 3.33Å; S461-C465 PolarHBondContact O-N 3.47Å; S461-C465 PolarHBondContact O-SG 2.97Å; Y462-C465 PolarHBondContact O-N 2.83Å
466R79.1Confident79.5Confident132 Ų13299.8 Ų99.850%0.49849%0.492SS..Hα-helixtrans-77.2-41.1179.1-163.3176.7178.1-177.1-2.9111.8Y462 F463 I464 K469 L470Y462-R466 WeakPolarHBondContact O-CB 3.24Å; Y462-R466 PolarHBondContact O-N 3.09Å; F463-R466 PolarHBondContact O-N 3.09Å; I464-R466 VanDerWaalsContact C-N 3.29Å; I464-R466 PolarHBondContact O-N 3.14Å; R466-K469 WeakPolarHBondContact O-CB 3.41Å; R466-K469 PolarHBondContact O-N 3.3Å; R466-K469 VanDerWaalsContact O-N 3.12Å; R466-L470 PolarHBondContact O-N 2.9Å
467T72.7Confident78.5Confident90 Ų9099.4 Ų99.455%0.55249%0.488SS*.Hα-helixtrans-64.6-37.2175.729.60000112.6F463 I464 K469 L470 K471F463-T467 PolarHBondContact O-N 3Å; F463-T467 PolarHBondContact O-OG1 3.07Å; I464-T467 WeakPolarHBondContact CA-OG1 3.23Å; I464-T467 PolarHBondContact O-OG1 3.2Å; I464-T467 VanDerWaalsContact O-OG1 3.11Å; T467-K469 PolarHBondContact O-N 3.39Å; T467-L470 PolarHBondContact O-N 3.31Å; T467-K471 PolarHBondContact O-N 2.85Å
468K66.1Low77.5Confident164 Ų164102.9 Ų102.971%0.71349%0.493SS*.THydrogen-bonded Turntrans-66.1-14.1172.5-78.8-171.9177.9-176.50114.8I464I464-K468 PolarHBondContact O-N 3.5Å; I464-K468 VanDerWaalsContact O-N 3.13Å
469K57.9Low76.3Confident149 Ų149105.5 Ų105.565%0.64851%0.508SS*.THydrogen-bonded Turntrans-95.9-12.4177.8-120.7-172.2-179.4-170.60113.3R466 T467R466-K469 WeakPolarHBondContact O-CB 3.41Å; R466-K469 PolarHBondContact O-N 3.3Å; R466-K469 VanDerWaalsContact O-N 3.12Å; T467-K469 PolarHBondContact O-N 3.39Å
470L54.9Low75Confident146 Ų146110.6 Ų110.676%0.76453%0.531SS*.THydrogen-bonded Turntrans-98.7-10.8179.8-88.7149.8000112.5R466 T467R466-L470 PolarHBondContact O-N 2.9Å; T467-L470 PolarHBondContact O-N 3.31Å
471K44.9Very low73.5Confident243 Ų243113.4 Ų113.4100%1.05754%0.536SS*.  trans-940158.5-73.6-176175.4-175.40108T467T467-K471 PolarHBondContact O-N 2.85Å

Retrieved 471 of 471 residues in 225 ms (Link to these results)