A0A093HNF4_STRCA Loading...

5-hydroxytryptamine receptor 2A

G-protein coupled receptor for 5-hydroxytryptamine (serotonin).

AlphaFold DB , UniProt , Accession A0A093HNF4, Species STRCA (Struthio camelus australis), Gene n/a, Length 471 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	32.4	Very low	26.2	Very low	223 Å²	223	152.5 Å²	152.5	100%	1.099	84%	0.838	S	S	*	*				0	60.7	0	-75.1	175.3	177.4	0	0	106.4
2	D	24.3	Very low	26.3	Very low	143 Å²	143	152.6 Å²	152.6	77%	0.765	84%	0.837	S	S	*	*				61.7	121.2	78.4	-51.6	-51.3	0	0	0	108.2
3	I	28.7	Very low	27.2	Very low	166 Å²	166	148.5 Å²	148.5	85%	0.851	82%	0.823	S	S	*	*				-160.3	143.6	68.2	-81.4	160.8	0	0	0	110.4
4	L	25.7	Very low	27	Very low	133 Å²	133	148.4 Å²	148.4	70%	0.696	83%	0.828	S	S	*	*			trans	-61.9	157.9	169.5	-137.8	85.4	0	0	0	112.5
5	C	26.8	Very low	27.2	Very low	131 Å²	131	144.6 Å²	144.6	89%	0.885	82%	0.823	S	S	*	*				-167.1	107	128.3	-98.7	0	0	0	0	109.7
6	D	24.6	Very low	28	Very low	133 Å²	133	145.6 Å²	145.6	71%	0.711	83%	0.826	S	S	*	*			trans	-65.3	153.5	160	-68.7	-55.5	0	0	0	111.2
7	E	26.8	Very low	28.3	Very low	201 Å²	201	143.4 Å²	143.4	94%	0.939	82%	0.821	S	S	*	*				-153.4	121.9	129.9	-123.6	177	-170.9	0	0	111.3
8	E	24.9	Very low	28.5	Very low	185 Å²	185	144.2 Å²	144.2	86%	0.864	82%	0.822	S	S	*	*			trans	-94.2	137.3	178.7	-151.8	178.4	-160.5	0	0	108.1
9	S	25	Very low	28.8	Very low	126 Å²	126	145.1 Å²	145.1	88%	0.881	82%	0.822	S	S	*	*			trans	-146.8	122	151.7	63.5	0	0	0	0	111.8
10	S	23.6	Very low	29	Very low	105 Å²	105	147.1 Å²	147.1	73%	0.734	82%	0.824	S	S	*	*			trans	-87.1	160.8	-176.7	53.9	0	0	0	0	113.6
11	V	25.9	Very low	29.1	Very low	131 Å²	131	147.6 Å²	147.6	79%	0.794	82%	0.824	S	S	*	*			trans	138.9	92	141.6	172.4	0	0	0	0	109.5
12	N	26.5	Very low	29	Very low	154 Å²	154	143.7 Å²	143.7	82%	0.824	81%	0.808	S	S	*	*				98.3	158.6	83.9	-111.5	8.6	0	0	0	113.5
13	P	38.2	Very low	29.2	Very low	100 Å²	100	145.9 Å²	145.9	65%	0.649	81%	0.813	S	S	*	*				-125.4	142	-123.7	34.3	-15.4	0	0	0	113.7
14	T	25.2	Very low	29.3	Very low	147 Å²	147	147.2 Å²	147.2	90%	0.902	82%	0.815	S	S	*	*			trans	-158.8	142	159.1	33.3	0	0	0	0	112.5
15	A	29.6	Very low	29.5	Very low	91 Å²	91	151.3 Å²	151.3	75%	0.752	82%	0.822	S	S	*	*			trans	87.4	75.3	158	0	0	0	0	0	117.8	S17	A15-S17 PolarHBondContact O-N 3.25Å; A15-S17 VanDerWaalsContact O-N 3.17Å
16	N	39.8	Very low	29.7	Very low	161 Å²	161	156.6 Å²	156.6	86%	0.861	82%	0.823	S	S	*	*			trans	-23.6	106.1	132.9	-75.9	-25.7	0	0	0	113.6
17	S	33.4	Very low	29.9	Very low	108 Å²	108	158 Å²	158	76%	0.755	83%	0.83	S	S	*	*			trans	-177.6	34.4	146.8	61.6	0	0	0	0	114.9	A15	A15-S17 PolarHBondContact O-N 3.25Å; A15-S17 VanDerWaalsContact O-N 3.17Å
18	L	30.8	Very low	29.9	Very low	158 Å²	158	160 Å²	160	83%	0.827	83%	0.83	S	S	*	*			trans	-141.6	23	177	-99.8	158.7	0	0	0	114.2	Q20	L18-Q20 VanDerWaalsContact C-N 3.32Å; L18-Q20 PolarHBondContact O-N 3.42Å
19	I	34.4	Very low	30	Very low	161 Å²	161	160.2 Å²	160.2	83%	0.826	83%	0.829	S	S	*	*			trans	-88.9	69.7	166.4	-54.1	175.2	0	0	0	108
20	Q	32.8	Very low	30	Very low	184 Å²	184	160.6 Å²	160.6	86%	0.86	82%	0.821	S	S	*	*	S	Bend	trans	-165.6	32.2	161.3	-133	171.2	-12	0	0	116.7	L18	L18-Q20 VanDerWaalsContact C-N 3.32Å; L18-Q20 PolarHBondContact O-N 3.42Å
21	L	31.4	Very low	30.2	Very low	159 Å²	159	162.7 Å²	162.7	83%	0.832	83%	0.829	S	S	*	*	S	Bend	trans	-147.8	17.4	175.2	-106.4	146.5	0	0	0	115.5
22	N	29.7	Very low	30.3	Very low	141 Å²	141	163.9 Å²	163.9	75%	0.754	83%	0.831	S	S	*	*			trans	-113.1	17.5	-174.1	-114.1	0.2	0	0	0	115.6
23	H	29.3	Very low	30.3	Very low	189 Å²	189	159.9 Å²	159.9	88%	0.875	83%	0.826	S	S	*	*	S	Bend	trans	-92.1	-7.4	178.5	-147	-58.5	0	0	0	114.7
24	E	31.5	Very low	30	Very low	193 Å²	193	161.4 Å²	161.4	90%	0.902	84%	0.836	S	S	*	*	S	Bend	trans	-112.4	44.7	178.4	-71.1	-156.1	146.4	0	0	113.7
25	R	29.9	Very low	30.3	Very low	219 Å²	219	158.7 Å²	158.7	83%	0.826	83%	0.829	S	S	*	*			trans	-139.4	31	172.4	-134	-173.6	-70.8	-175.7	-1	115.4
26	R	30	Very low	30.5	Very low	242 Å²	242	162.4 Å²	162.4	91%	0.913	84%	0.836	S	S	*	*			trans	-118.9	78.7	166.4	-79.4	-167.1	-169.7	178.3	5	111
27	L	30	Very low	30.2	Very low	164 Å²	164	162.3 Å²	162.3	86%	0.859	83%	0.833	S	S	*	*	S	Bend	trans	-173.7	84.5	149.1	-105.1	145.7	0	0	0	107.1
28	Y	25.3	Very low	29.9	Very low	242 Å²	242	164.8 Å²	164.8	95%	0.949	84%	0.838	S	S	*	*			trans	178.8	82.4	142.8	-101.6	-74.2	0	0	0	106.2
29	K	27	Very low	29.9	Very low	190 Å²	190	165.1 Å²	165.1	83%	0.826	84%	0.84	S	S	*	*			trans	-99.3	135.8	163.4	-126.2	-178.8	-177.3	-176.9	0	106.6
30	N	26.7	Very low	29.8	Very low	134 Å²	134	162.1 Å²	162.1	72%	0.717	83%	0.833	S	S	*	*			trans	93.7	82.8	163.5	-56.3	-4.8	0	0	0	117.3
31	V	27.3	Very low	29.9	Very low	149 Å²	149	162 Å²	162	90%	0.903	83%	0.832	S	S	*	*			trans	-127.9	116.7	131.8	179.9	0	0	0	0	106.9
32	N	27.5	Very low	29.9	Very low	155 Å²	155	161 Å²	161	83%	0.829	83%	0.827	S	S	*	*			trans	-80.3	133.5	176.4	-73	-20.3	0	0	0	109.7
33	G	26.6	Very low	30.2	Very low	71 Å²	71	161.7 Å²	161.7	73%	0.732	82%	0.824	S	S	*	*			trans	174.9	133.5	167	0	0	0	0	0	112
34	P	32.8	Very low	29.9	Very low	132 Å²	132	160.8 Å²	160.8	86%	0.857	83%	0.825	S	S	*	*			trans	-92.7	135.4	-167.5	35.7	-30.3	0	0	0	111.8
35	A	30.2	Very low	29.9	Very low	90 Å²	90	157.7 Å²	157.7	74%	0.744	81%	0.814	S	S	*	*			trans	174.4	122.8	144	0	0	0	0	0	109.7
36	D	34.4	Very low	29.8	Very low	169 Å²	169	153.9 Å²	153.9	90%	0.904	82%	0.815	S	S	*	*			trans	-59.1	129.4	172.2	-57.9	-58.5	0	0	0	111.6
37	I	34	Very low	29.8	Very low	158 Å²	158	148.5 Å²	148.5	81%	0.81	81%	0.809	S	S	*	*			trans	-132.7	114.6	164.3	-56.1	179.9	0	0	0	109.2	L39	I37-L39 PolarHBondContact O-N 3.26Å
38	N	25.9	Very low	29.7	Very low	160 Å²	160	148.4 Å²	148.4	86%	0.856	81%	0.81	S	S	*	*			trans	-59.6	124.1	176.8	-101.4	-35.6	0	0	0	111.8	S40	N38-S40 PolarHBondContact O-N 2.88Å
39	L	31.9	Very low	30.3	Very low	166 Å²	166	141.6 Å²	141.6	87%	0.869	80%	0.797	S	S	*	*			trans	-98.1	70.9	-176.2	-159.3	80.4	0	0	0	110.9	I37	I37-L39 PolarHBondContact O-N 3.26Å
40	S	32.5	Very low	30.9	Very low	97 Å²	97	141 Å²	141	68%	0.678	80%	0.798	S	S	*	*			trans	-136.8	10.4	176.3	67.3	0	0	0	0	115.3	N38	N38-S40 PolarHBondContact O-N 2.88Å
41	H	34.8	Very low	31.1	Very low	181 Å²	181	142.1 Å²	142.1	84%	0.838	80%	0.803	S	S	*	*	S	Bend	trans	-122.8	11.1	-179.8	-90.8	-72	0	0	0	116
42	L	30.4	Very low	31.8	Very low	139 Å²	139	143.2 Å²	143.2	73%	0.728	80%	0.803	S	S	*	*			trans	-104.8	114	175	-95.9	99.6	0	0	0	112.7
43	F	35.6	Very low	32.2	Very low	156 Å²	156	141.6 Å²	141.6	68%	0.684	80%	0.799	S	S	*	*			trans	97.7	94.4	159.7	-65.4	-75.5	0	0	0	119	L45	F43-L45 HydrophobicContact CD1-CD1 3.38Å; F43-L45 HydrophobicContact CD1-CG 3.96Å; F43-L45 HydrophobicContact CE1-CD1 3.79Å; F43-L45 HydrophobicContact CG-CD1 4.2Å
44	N	24.7	Very low	32.5	Very low	169 Å²	169	145.5 Å²	145.5	90%	0.904	80%	0.803	S	S	*	*			trans	-94.6	107.7	138.4	-98.8	-6.1	0	0	0	107.4
45	L	31.1	Very low	32.6	Very low	129 Å²	129	147 Å²	147	68%	0.675	80%	0.803	S	S	*	*			trans	-108.4	102.3	173	-107.5	152.9	0	0	0	108.2	F43	F43-L45 HydrophobicContact CD1-CD1 3.38Å; F43-L45 HydrophobicContact CD1-CG 3.96Å; F43-L45 HydrophobicContact CE1-CD1 3.79Å; F43-L45 HydrophobicContact CG-CD1 4.2Å
46	T	26.6	Very low	32.6	Very low	138 Å²	138	148.3 Å²	148.3	85%	0.847	81%	0.807	S	S	*	*			trans	-87.8	115.6	162.9	46.5	0	0	0	0	107.9
47	V	31.1	Very low	32.7	Very low	129 Å²	129	145.9 Å²	145.9	78%	0.782	80%	0.802	S	S	*	*			trans	-86.8	109.4	176.4	177.6	0	0	0	0	107.7
48	D	27	Very low	32.7	Very low	163 Å²	163	147.8 Å²	147.8	87%	0.872	81%	0.807	S	S	*	*			trans	-96.9	119.6	166.3	-126	-11.8	0	0	0	108.6	E50	D48-E50 PolarHBondContact O-N 3.47Å
49	S	39.2	Very low	33.4	Very low	99 Å²	99	144.4 Å²	144.4	69%	0.692	80%	0.802	S	S	*	*			trans	-87.3	93	-179.6	64.4	0	0	0	0	109.4
50	E	38.1	Very low	33.8	Very low	178 Å²	178	144.1 Å²	144.1	83%	0.832	80%	0.801	S	S	*	*	S	Bend	trans	169.6	132.8	149.6	-94.1	161.6	-161.4	0	0	109	D48	D48-E50 PolarHBondContact O-N 3.47Å
51	N	31.5	Very low	34	Very low	156 Å²	156	148.5 Å²	148.5	83%	0.834	81%	0.813	S	S	*	*			trans	83.3	75.3	179.7	-60.7	-23	0	0	0	118.5	T53	N51-T53 PolarHBondContact O-N 3.21Å
52	L	42.1	Very low	34.2	Very low	173 Å²	173	145.4 Å²	145.4	91%	0.906	81%	0.812	S	S	*	*			trans	-87.1	74.4	167.3	-163.2	85	0	0	0	111.8
53	T	36.6	Very low	34.6	Very low	121 Å²	121	144.1 Å²	144.1	74%	0.742	81%	0.812	S	S	*	*			trans	-143.6	-6.8	169.4	43.7	0	0	0	0	118	N51	N51-T53 PolarHBondContact O-N 3.21Å
54	N	32.1	Very low	34.8	Very low	152 Å²	152	142.3 Å²	142.3	81%	0.813	82%	0.816	S	S	*	*			trans	-127.5	94.7	-179.8	-73.1	-22.2	0	0	0	112.3
55	L	35.1	Very low	35.4	Very low	164 Å²	164	140.1 Å²	140.1	86%	0.859	81%	0.812	S	S	*	*			trans	-110.1	102.2	157	-105.4	81.6	0	0	0	108.5
56	S	29.8	Very low	35.6	Very low	117 Å²	117	143.8 Å²	143.8	82%	0.818	82%	0.819	S	S	*	*			trans	-89.5	118.9	165.4	51.8	0	0	0	0	108.9
57	C	37.8	Very low	36.1	Very low	119 Å²	119	142.9 Å²	142.9	80%	0.804	82%	0.818	S	S	*	*			trans	-90	109.6	169.4	-63.3	0	0	0	0	108.7	A59	C57-A59 PolarHBondContact O-N 3.14Å
58	E	32.9	Very low	36.5	Very low	197 Å²	197	140.4 Å²	140.4	92%	0.921	81%	0.806	S	S	*	*			trans	-70.8	115.8	165.2	-103.5	174.9	160.4	0	0	108.7	N60	E58-N60 PolarHBondContact O-N 3.48Å
59	A	40.9	Very low	37.1	Very low	89 Å²	89	140.2 Å²	140.2	74%	0.736	81%	0.805	S	S	*	*			trans	-71.2	119.9	178.2	0	0	0	0	0	109.6	C57	C57-A59 PolarHBondContact O-N 3.14Å
60	N	40.7	Very low	37.1	Very low	160 Å²	160	144.7 Å²	144.7	86%	0.856	81%	0.812	S	S	*	*	S	Bend	trans	-161.9	115.3	140	-88.3	-28.5	0	0	0	109.2	E58	E58-N60 PolarHBondContact O-N 3.48Å
61	M	36.8	Very low	37.1	Very low	189 Å²	189	145 Å²	145	93%	0.931	81%	0.813	S	S	*	*	S	Bend	trans	77.8	113.7	-179.2	-68.1	159	67.8	0	0	116.6
62	S	38.9	Very low	37.6	Very low	117 Å²	117	144.2 Å²	144.2	82%	0.818	81%	0.809	S	S	*	*			trans	-67.4	141.6	175.9	37.5	0	0	0	0	112.7
63	P	39.1	Very low	38	Very low	112 Å²	112	141.4 Å²	141.4	73%	0.727	80%	0.803	S	S	*	*				-126.3	166.4	95	34.8	-25.7	0	0	0	111.4	C65	P63-C65 PolarHBondContact O-N 3.02Å
64	P	39.1	Very low	39.2	Very low	117 Å²	117	143.6 Å²	143.6	76%	0.76	81%	0.805	S	S	*	*			trans	-68.8	111	-179.4	28.3	-31.1	0	0	0	108.9	Y66	P64-Y66 PolarHBondContact O-N 3.41Å
65	C	37.4	Very low	40.8	Very low	124 Å²	124	143.9 Å²	143.9	84%	0.838	80%	0.799	S	S	*	*			trans	-58	111.9	161.7	-105.7	0	0	0	0	107.4	P63 S67	P63-C65 PolarHBondContact O-N 3.02Å; C65-S67 VanDerWaalsContact C-N 3.3Å; C65-S67 PolarHBondContact O-N 3.49Å
66	Y	34.3	Very low	42.8	Very low	206 Å²	206	140.7 Å²	140.7	81%	0.808	78%	0.783	S	S	*	*			trans	-58.5	95.5	168.6	-115.4	-99.5	0	0	0	107.9	P64 S68	P64-Y66 PolarHBondContact O-N 3.41Å; Y66-S68 WeakPolarHBondContact CD1-OG 3.44Å; Y66-S68 PolarHBondContact O-N 2.98Å
67	S	37.3	Very low	45.4	Very low	118 Å²	118	142.9 Å²	142.9	83%	0.825	77%	0.773	S	S	*	*			trans	-69.3	59.1	168.2	44	0	0	0	0	110.3	C65	C65-S67 VanDerWaalsContact C-N 3.3Å; C65-S67 PolarHBondContact O-N 3.49Å
68	S	39.7	Very low	47.5	Very low	78 Å²	78	140.9 Å²	140.9	55%	0.545	76%	0.759	S	S	.	*			trans	-117	21.9	-174.1	60.9	0	0	0	0	113.9	Y66	Y66-S68 WeakPolarHBondContact CD1-OG 3.44Å; Y66-S68 PolarHBondContact O-N 2.98Å
69	L	39.2	Very low	49.9	Very low	159 Å²	159	132 Å²	132	83%	0.832	72%	0.719	S	S	*	*	S	Bend	trans	-112.8	-2.6	-178.7	-97.8	163	0	0	0	116.4
70	F	38.7	Very low	52.1	Low	192 Å²	192	132.1 Å²	132.1	84%	0.842	71%	0.707	S	S	*	*			trans	-162.9	68.1	164.6	-119.8	-86.2	0	0	0	109.3	L72	F70-L72 VanDerWaalsContact C-N 3.26Å; F70-L72 PolarHBondContact O-N 3.06Å
71	Q	38.3	Very low	54.5	Low	184 Å²	184	129.9 Å²	129.9	86%	0.86	69%	0.694	S	S	*	*			trans	-66.6	99.6	160.1	-151.5	171.5	7.6	0	0	104.7	S73	Q71-S73 PolarHBondContact O-N 3.34Å; Q71-S73 VanDerWaalsContact O-N 3.11Å
72	L	43.6	Very low	57.2	Low	141 Å²	141	121.2 Å²	121.2	74%	0.738	65%	0.652	S	S	*	*			trans	-44	125.7	172.9	-90.8	93.5	0	0	0	107.2	F70 E74	F70-L72 VanDerWaalsContact C-N 3.26Å; F70-L72 PolarHBondContact O-N 3.06Å; L72-E74 VanDerWaalsContact C-N 3.29Å; L72-E74 PolarHBondContact O-N 2.91Å
73	S	49.9	Very low	59.8	Low	113 Å²	113	118.7 Å²	118.7	79%	0.79	63%	0.632	S	S	*	*			trans	-50.3	95.1	172.1	175.5	0	0	0	0	108.8	Q71 K75	Q71-S73 PolarHBondContact O-N 3.34Å; Q71-S73 VanDerWaalsContact O-N 3.11Å; S73-K75 PolarHBondContact O-N 3.31Å
74	E	60.6	Low	62.5	Low	167 Å²	167	117.5 Å²	117.5	78%	0.78	62%	0.618	S	S	*	*			trans	-58.4	127.1	168	-74	-156.6	163	0	0	106.8	L72 N76	L72-E74 VanDerWaalsContact C-N 3.29Å; L72-E74 PolarHBondContact O-N 2.91Å; E74-N76 PolarHBondContact O-N 3.09Å
75	K	65.8	Low	65.2	Low	159 Å²	159	113 Å²	113	69%	0.691	59%	0.588	S	S	*	*			trans	-68.5	108.8	-178.9	-67.9	-179.5	-178.8	176.2	0	107.7	S73 W77	S73-K75 PolarHBondContact O-N 3.31Å; K75-W77 HydrophobicContact CD-CZ2 4.08Å; K75-W77 PolarHBondContact O-N 3.23Å
76	N	77.3	Confident	68.1	Low	97 Å²	97	108 Å²	108	52%	0.519	55%	0.553	S	S	.	*			trans	-73.1	68.5	175.3	-74.1	-28	0	0	0	111.4	E74 P78 A79 L80	E74-N76 PolarHBondContact O-N 3.09Å; N76-P78 VanDerWaalsContact C-N 3.29Å; N76-A79 HydrophobicContact CB-CB 3.97Å; N76-A79 WeakPolarHBondContact O-CB 3.5Å; N76-A79 PolarHBondContact O-N 3.39Å; N76-L80 PolarHBondContact O-N 2.87Å; N76-L80 VanDerWaalsContact O-N 3.15Å
77	W	84.6	Confident	71.1	Confident	163 Å²	163	102.3 Å²	102.3	62%	0.617	54%	0.54	S	S	*	.	H	α-helix	trans	-51.8	-38.4	174.1	-68.5	111.1	0	0	0	114	K75 A79 L80 L81	K75-W77 HydrophobicContact CD-CZ2 4.08Å; K75-W77 PolarHBondContact O-N 3.23Å; W77-A79 PolarHBondContact O-N 3.02Å; W77-L80 HydrophobicContact CE3-CD2 3.92Å; W77-L80 HydrophobicContact CZ3-CD2 3.81Å; W77-L80 PolarHBondContact O-N 3.33Å; W77-L81 PolarHBondContact O-N 3.49Å; W77-L81 VanDerWaalsContact O-N 3.07Å
78	P	81.6	Confident	73.9	Confident	77 Å²	77	101.5 Å²	101.5	50%	0.5	53%	0.526	S	S	.	.	H	α-helix	trans	-58.9	-45.2	174	-24.9	35.6	0	0	0	112.1	N76 L80 L81 T82	N76-P78 VanDerWaalsContact C-N 3.29Å; P78-L80 VanDerWaalsContact C-N 3.32Å; P78-L80 PolarHBondContact O-N 2.94Å; P78-L81 PolarHBondContact O-N 3Å; P78-T82 WeakPolarHBondContact O-CG2 3.28Å; P78-T82 PolarHBondContact O-N 2.88Å; P78-T82 PolarHBondContact O-OG1 2.88Å
79	A	83.8	Confident	76.7	Confident	11 Å²	11	97.8 Å²	97.8	9%	0.091	50%	0.5	C	S	.	.	H	α-helix	trans	-64.8	-34.5	178.7	0	0	0	0	0	112.6	N76 W77 T82 V83 L137	N76-A79 HydrophobicContact CB-CB 3.97Å; N76-A79 WeakPolarHBondContact O-CB 3.5Å; N76-A79 PolarHBondContact O-N 3.39Å; W77-A79 PolarHBondContact O-N 3.02Å; A79-T82 WeakPolarHBondContact CA-OG1 3.35Å; A79-T82 PolarHBondContact O-N 2.86Å; A79-T82 PolarHBondContact O-OG1 3.02Å; A79-V83 WeakPolarHBondContact O-CG2 3.25Å; A79-V83 PolarHBondContact O-N 2.97Å; A79-L137 HydrophobicContact CB-CD2 3.72Å
80	L	88.1	Confident	79.5	Confident	90 Å²	90	92 Å²	92	47%	0.471	47%	0.469	S	S	.	.	H	α-helix	trans	-65.8	-43.8	174.3	-179.4	63.4	0	0	0	111.8	N76 W77 P78 T82 V83 I84	N76-L80 PolarHBondContact O-N 2.87Å; N76-L80 VanDerWaalsContact O-N 3.15Å; W77-L80 HydrophobicContact CE3-CD2 3.92Å; W77-L80 HydrophobicContact CZ3-CD2 3.81Å; W77-L80 PolarHBondContact O-N 3.33Å; P78-L80 VanDerWaalsContact C-N 3.32Å; P78-L80 PolarHBondContact O-N 2.94Å; L80-T82 VanDerWaalsContact C-N 3.32Å; L80-T82 PolarHBondContact O-N 2.9Å; L80-V83 PolarHBondContact O-N 3Å; L80-I84 WeakPolarHBondContact O-CG1 3.25Å; L80-I84 PolarHBondContact O-N 3.32Å
81	L	91.1	Very high	82.3	Confident	114 Å²	114	85.2 Å²	85.2	60%	0.597	45%	0.448	S	S	*	.	H	α-helix	trans	-61.7	-41	177.5	-79.9	168.4	0	0	0	111.6	W77 P78 I84 V85	W77-L81 PolarHBondContact O-N 3.49Å; W77-L81 VanDerWaalsContact O-N 3.07Å; P78-L81 PolarHBondContact O-N 3Å; L81-I84 PolarHBondContact O-N 2.96Å; L81-V85 WeakPolarHBondContact O-CG2 3.47Å; L81-V85 PolarHBondContact O-N 3.3Å; L81-V85 VanDerWaalsContact O-N 3.09Å
82	T	92.3	Very high	85.2	Confident	7 Å²	7	77 Å²	77	4%	0.043	41%	0.413	C	S	.	.	H	α-helix	trans	-66.1	-38.3	179.2	57.2	0	0	0	0	112.5	P78 A79 L80 I84 V85 I86 M133 I136 W367	P78-T82 WeakPolarHBondContact O-CG2 3.28Å; P78-T82 PolarHBondContact O-N 2.88Å; P78-T82 PolarHBondContact O-OG1 2.88Å; A79-T82 WeakPolarHBondContact CA-OG1 3.35Å; A79-T82 PolarHBondContact O-N 2.86Å; A79-T82 PolarHBondContact O-OG1 3.02Å; L80-T82 VanDerWaalsContact C-N 3.32Å; L80-T82 PolarHBondContact O-N 2.9Å; T82-I84 VanDerWaalsContact C-N 3.32Å; T82-I84 PolarHBondContact O-N 2.95Å; T82-V85 PolarHBondContact O-N 3.28Å; T82-I86 VanDerWaalsContact O-CG1 3.26Å; T82-I86 WeakPolarHBondContact O-CG1 3.28Å; T82-I86 PolarHBondContact O-N 2.97Å; T82-M133 WeakPolarHBondContact OG1-CG 3.48Å; T82-I136 HydrophobicContact CG2-CD1 4.15Å; T82-W367 VanDerWaalsContact CB-CZ3 3.49Å; T82-W367 HydrophobicContact CG2-CD2 3.48Å; T82-W367 VanDerWaalsContact CG2-CD2 3.48Å; T82-W367 HydrophobicContact CG2-CE3 3.59Å; T82-W367 HydrophobicContact CG2-CG 4.26Å; T82-W367 HydrophobicContact CG2-CH2 3.49Å; T82-W367 VanDerWaalsContact CG2-CH2 3.49Å; T82-W367 HydrophobicContact CG2-CZ2 3.35Å; T82-W367 HydrophobicContact CG2-CZ3 3.58Å
83	V	94.9	Very high	87.8	Confident	64 Å²	64	70.3 Å²	70.3	39%	0.388	38%	0.378	S	S	.	.	H	α-helix	trans	-58.1	-44.1	172.4	172.1	0	0	0	0	111.5	A79 L80 V85 I86 V87 M133	A79-V83 WeakPolarHBondContact O-CG2 3.25Å; A79-V83 PolarHBondContact O-N 2.97Å; L80-V83 PolarHBondContact O-N 3Å; V83-V85 VanDerWaalsContact C-N 3.34Å; V83-V85 PolarHBondContact O-N 3.47Å; V83-I86 PolarHBondContact O-N 3.5Å; V83-V87 HydrophobicContact CG1-CG2 4.46Å; V83-V87 WeakPolarHBondContact O-CG2 3.49Å; V83-V87 PolarHBondContact O-N 3.48Å; V83-M133 HydrophobicContact CG2-SD 3.42Å; V83-M133 WeakPolarHBondContact CG2-SD 3.3Å
84	I	95.1	Very high	90	Very high	86 Å²	86	68.2 Å²	68.2	44%	0.441	36%	0.357	S	S	.	.	H	α-helix	trans	-61.2	-45.4	178.1	-65.5	167.6	0	0	0	110.3	L80 L81 T82 I86 V87 L88	L80-I84 WeakPolarHBondContact O-CG1 3.25Å; L80-I84 PolarHBondContact O-N 3.32Å; L81-I84 PolarHBondContact O-N 2.96Å; T82-I84 VanDerWaalsContact C-N 3.32Å; T82-I84 PolarHBondContact O-N 2.95Å; I84-I86 PolarHBondContact O-N 3.47Å; I84-V87 PolarHBondContact O-N 3.49Å; I84-L88 HydrophobicContact CG2-CD1 3.88Å; I84-L88 HydrophobicContact CG2-CG 4.34Å; I84-L88 WeakPolarHBondContact O-CB 3.45Å; I84-L88 VanDerWaalsContact O-CG 3.3Å; I84-L88 WeakPolarHBondContact O-CG 3.4Å; I84-L88 PolarHBondContact O-N 3.21Å
85	V	96.3	Very high	91.8	Very high	23 Å²	23	61.7 Å²	61.7	14%	0.139	33%	0.328	C	S	.	.	H	α-helix	trans	-61.4	-43.3	177.7	175.8	0	0	0	0	111.3	L81 T82 V83 L88 T89 M129 L371	L81-V85 WeakPolarHBondContact O-CG2 3.47Å; L81-V85 PolarHBondContact O-N 3.3Å; L81-V85 VanDerWaalsContact O-N 3.09Å; T82-V85 PolarHBondContact O-N 3.28Å; V83-V85 VanDerWaalsContact C-N 3.34Å; V83-V85 PolarHBondContact O-N 3.47Å; V85-L88 PolarHBondContact O-N 3.32Å; V85-T89 WeakPolarHBondContact O-CB 3.45Å; V85-T89 PolarHBondContact O-N 3.09Å; V85-T89 PolarHBondContact O-OG1 3.26Å; V85-M129 HydrophobicContact CG1-SD 4.42Å; V85-L371 HydrophobicContact CG1-CD1 4.25Å; V85-L371 HydrophobicContact CG2-CD1 4.05Å
86	I	97.9	Very high	93.3	Very high	18 Å²	18	54.1 Å²	54.1	9%	0.092	30%	0.295	C	S	.	.	H	α-helix	trans	-58.8	-50.6	177.1	-70.6	163.6	0	0	0	110.6	T82 V83 I84 L88 T89 I90 M129 P130 M133 W367	T82-I86 VanDerWaalsContact O-CG1 3.26Å; T82-I86 WeakPolarHBondContact O-CG1 3.28Å; T82-I86 PolarHBondContact O-N 2.97Å; V83-I86 PolarHBondContact O-N 3.5Å; I84-I86 PolarHBondContact O-N 3.47Å; I86-L88 PolarHBondContact O-N 3.41Å; I86-T89 PolarHBondContact O-N 3.49Å; I86-I90 HydrophobicContact CG2-CD1 3.73Å; I86-I90 WeakPolarHBondContact O-CG1 3.33Å; I86-I90 PolarHBondContact O-N 2.79Å; I86-M129 HydrophobicContact CD1-CB 4.1Å; I86-M129 HydrophobicContact CG1-CB 3.6Å; I86-M129 HydrophobicContact CG1-SD 4.28Å; I86-P130 HydrophobicContact CD1-CG 4.31Å; I86-P130 HydrophobicContact CG2-CG 4.42Å; I86-M133 HydrophobicContact CD1-CB 4.35Å; I86-M133 HydrophobicContact CD1-SD 4.25Å; I86-W367 HydrophobicContact CD1-CH2 4.38Å
87	V	97.6	Very high	94.3	Very high	88 Å²	88	51.1 Å²	51.1	53%	0.533	28%	0.278	S	S	.	.	H	α-helix	trans	-62.2	-45.8	-178.6	172.2	0	0	0	0	111.1	V83 I84 T89 I90 A91	V83-V87 HydrophobicContact CG1-CG2 4.46Å; V83-V87 WeakPolarHBondContact O-CG2 3.49Å; V83-V87 PolarHBondContact O-N 3.48Å; I84-V87 PolarHBondContact O-N 3.49Å; V87-T89 VanDerWaalsContact C-N 3.33Å; V87-T89 PolarHBondContact O-N 3.14Å; V87-I90 PolarHBondContact O-N 2.87Å; V87-A91 WeakPolarHBondContact O-CB 3.42Å; V87-A91 PolarHBondContact O-N 3.23Å
88	L	96.7	Very high	94.8	Very high	101 Å²	101	46 Å²	46	53%	0.529	26%	0.262	S	S	.	.	H	α-helix	trans	-62.5	-40.9	177.6	-70.6	175.6	0	0	0	112	I84 V85 I86 G92 A374	I84-L88 HydrophobicContact CG2-CD1 3.88Å; I84-L88 HydrophobicContact CG2-CG 4.34Å; I84-L88 WeakPolarHBondContact O-CB 3.45Å; I84-L88 VanDerWaalsContact O-CG 3.3Å; I84-L88 WeakPolarHBondContact O-CG 3.4Å; I84-L88 PolarHBondContact O-N 3.21Å; V85-L88 PolarHBondContact O-N 3.32Å; I86-L88 PolarHBondContact O-N 3.41Å; L88-G92 WeakPolarHBondContact O-CA 3.44Å; L88-G92 PolarHBondContact O-N 3.32Å; L88-A374 HydrophobicContact CB-CB 4.4Å
89	T	97.8	Very high	95.5	Very high	0 Å²	0	42.3 Å²	42.3	0%	0	24%	0.238	C	C	.	.	H	α-helix	trans	-62.5	-51.5	178.3	-56.5	0	0	0	0	111.1	V85 I86 V87 N93 D121 M129 A374	V85-T89 WeakPolarHBondContact O-CB 3.45Å; V85-T89 PolarHBondContact O-N 3.09Å; V85-T89 PolarHBondContact O-OG1 3.26Å; I86-T89 PolarHBondContact O-N 3.49Å; V87-T89 VanDerWaalsContact C-N 3.33Å; V87-T89 PolarHBondContact O-N 3.14Å; T89-N93 WeakPolarHBondContact O-CB 3.33Å; T89-N93 PolarHBondContact O-N 2.72Å; T89-N93 VanDerWaalsContact O-N 3.15Å; T89-N93 PolarHBondContact O-ND2 3.04Å; T89-D121 WeakPolarHBondContact CG2-O 3.49Å; T89-M129 HydrophobicContact CG2-CE 3.91Å; T89-M129 HydrophobicContact CG2-SD 4.49Å; T89-A374 WeakPolarHBondContact OG1-CB 3.45Å
90	I	98.4	Very high	96	Very high	38 Å²	38	41.9 Å²	41.9	20%	0.195	23%	0.234	C	C	.	.	H	α-helix	trans	-66.2	-52.9	-177.9	-64.7	169	0	0	0	110.2	I86 V87 G92 N93 I94 F126	I86-I90 HydrophobicContact CG2-CD1 3.73Å; I86-I90 WeakPolarHBondContact O-CG1 3.33Å; I86-I90 PolarHBondContact O-N 2.79Å; V87-I90 PolarHBondContact O-N 2.87Å; I90-G92 PolarHBondContact O-N 3.44Å; I90-N93 PolarHBondContact O-N 3.04Å; I90-I94 HydrophobicContact CG2-CD1 3.62Å; I90-I94 HydrophobicContact CG2-CG1 4.43Å; I90-I94 WeakPolarHBondContact O-CB 3.46Å; I90-I94 VanDerWaalsContact O-CG1 3.23Å; I90-I94 WeakPolarHBondContact O-CG1 3.06Å; I90-I94 PolarHBondContact O-N 3.39Å; I90-F126 HydrophobicContact CD1-CB 4.36Å; I90-F126 HydrophobicContact CD1-CD2 4.24Å
91	A	97.8	Very high	96.3	Very high	48 Å²	48	40.5 Å²	40.5	40%	0.397	23%	0.232	S	C	.	.	H	α-helix	trans	-63.3	-44.4	-176.2	0	0	0	0	0	112.1	V87 I94 L95	V87-A91 WeakPolarHBondContact O-CB 3.42Å; V87-A91 PolarHBondContact O-N 3.23Å; A91-I94 PolarHBondContact O-N 3.46Å; A91-L95 WeakPolarHBondContact O-CG 3.32Å; A91-L95 PolarHBondContact O-N 3.45Å; A91-L95 VanDerWaalsContact O-N 3.08Å
92	G	97.4	Very high	96.3	Very high	12 Å²	12	39.9 Å²	39.9	12%	0.124	23%	0.229	C	C	.	.	H	α-helix	trans	-61.9	-45.2	179.5	0	0	0	0	0	112.2	L88 I90 L95 V96 P377	L88-G92 WeakPolarHBondContact O-CA 3.44Å; L88-G92 PolarHBondContact O-N 3.32Å; I90-G92 PolarHBondContact O-N 3.44Å; G92-L95 WeakPolarHBondContact O-CB 3.49Å; G92-L95 PolarHBondContact O-N 3.25Å; G92-V96 PolarHBondContact O-N 3.39Å; G92-V96 VanDerWaalsContact O-N 3.16Å; G92-P377 WeakPolarHBondContact O-CG 3.32Å
93	N	98.1	Very high	96.3	Very high	0 Å²	0	40.1 Å²	40.1	0%	0	23%	0.23	C	C	.	.	H	α-helix	trans	-73	-32.4	-179.5	-75	-63.4	0	0	0	112.8	T89 I90 L95 V96 I97 A118 M122 S373	T89-N93 WeakPolarHBondContact O-CB 3.33Å; T89-N93 PolarHBondContact O-N 2.72Å; T89-N93 VanDerWaalsContact O-N 3.15Å; T89-N93 PolarHBondContact O-ND2 3.04Å; I90-N93 PolarHBondContact O-N 3.04Å; N93-L95 VanDerWaalsContact C-N 3.31Å; N93-L95 PolarHBondContact O-N 3.43Å; N93-V96 WeakPolarHBondContact O-CB 3.48Å; N93-V96 PolarHBondContact O-N 3.27Å; N93-I97 VanDerWaalsContact O-CG1 3.31Å; N93-I97 WeakPolarHBondContact O-CG1 3.4Å; N93-I97 PolarHBondContact O-N 3.38Å; N93-A118 HydrophobicContact CB-CB 4.05Å; N93-A118 WeakPolarHBondContact CB-O 3.49Å; N93-A118 WeakPolarHBondContact OD1-CA 3.5Å; N93-A118 WeakPolarHBondContact OD1-CB 3.22Å; N93-M122 HydrophobicContact CB-CB 4.06Å; N93-S373 PolarHBondContact ND2-O 2.95Å
94	I	98.1	Very high	96	Very high	69 Å²	69	45.5 Å²	45.5	35%	0.354	25%	0.248	S	C	.	.	H	α-helix	trans	-59.2	-42.5	168.7	-70.6	168.4	0	0	0	110.9	I90 A91 V96 I97 M98 M122	I90-I94 HydrophobicContact CG2-CD1 3.62Å; I90-I94 HydrophobicContact CG2-CG1 4.43Å; I90-I94 WeakPolarHBondContact O-CB 3.46Å; I90-I94 VanDerWaalsContact O-CG1 3.23Å; I90-I94 WeakPolarHBondContact O-CG1 3.06Å; I90-I94 PolarHBondContact O-N 3.39Å; A91-I94 PolarHBondContact O-N 3.46Å; I94-V96 VanDerWaalsContact C-N 3.33Å; I94-V96 PolarHBondContact O-N 3.31Å; I94-I97 PolarHBondContact O-N 3.14Å; I94-M98 HydrophobicContact CG2-CE 4.07Å; I94-M98 HydrophobicContact CG2-CG 4.41Å; I94-M98 HydrophobicContact CG2-SD 4.42Å; I94-M98 WeakPolarHBondContact O-CG 3.41Å; I94-M98 PolarHBondContact O-N 3.07Å; I94-M122 HydrophobicContact CD1-SD 4.41Å; I94-M122 HydrophobicContact CG1-CG 4.46Å; I94-M122 HydrophobicContact CG1-SD 3.69Å
95	L	97.1	Very high	95.6	Very high	30 Å²	30	49.3 Å²	49.3	16%	0.157	26%	0.261	C	S	.	.	H	α-helix	trans	-60.8	-40.6	175.7	-70.2	168.5	0	0	0	112	A91 G92 N93 M98 A99 F391 Y394	A91-L95 WeakPolarHBondContact O-CG 3.32Å; A91-L95 PolarHBondContact O-N 3.45Å; A91-L95 VanDerWaalsContact O-N 3.08Å; G92-L95 WeakPolarHBondContact O-CB 3.49Å; G92-L95 PolarHBondContact O-N 3.25Å; N93-L95 VanDerWaalsContact C-N 3.31Å; N93-L95 PolarHBondContact O-N 3.43Å; L95-M98 HydrophobicContact CD2-CE 3.69Å; L95-M98 HydrophobicContact CG-CE 4.45Å; L95-M98 PolarHBondContact O-N 3.43Å; L95-A99 WeakPolarHBondContact O-CB 3.41Å; L95-A99 PolarHBondContact O-N 3.48Å; L95-F391 VanDerWaalsContact C-CE1 3.44Å; L95-F391 HydrophobicContact CB-CD1 4Å; L95-F391 HydrophobicContact CB-CD2 4.09Å; L95-F391 HydrophobicContact CB-CE1 3.79Å; L95-F391 HydrophobicContact CB-CE2 3.92Å; L95-F391 HydrophobicContact CB-CG 4.17Å; L95-F391 HydrophobicContact CB-CZ 3.77Å; L95-F391 HydrophobicContact CD1-CD2 4.12Å; L95-F391 HydrophobicContact CD1-CG 4.43Å; L95-F391 VanDerWaalsContact O-CE1 3.22Å; L95-F391 WeakPolarHBondContact O-CE1 3.28Å; L95-Y394 HydrophobicContact CD2-CD2 4.25Å
96	V	97.1	Very high	95.2	Very high	0 Å²	0	48.5 Å²	48.5	0%	0	26%	0.256	C	S	.	.	H	α-helix	trans	-61.1	-48.8	174.7	178.1	0	0	0	0	110.7	G92 N93 I94 M98 A99 V100 A118 P377 Y380 Y387 F391	G92-V96 PolarHBondContact O-N 3.39Å; G92-V96 VanDerWaalsContact O-N 3.16Å; N93-V96 WeakPolarHBondContact O-CB 3.48Å; N93-V96 PolarHBondContact O-N 3.27Å; I94-V96 VanDerWaalsContact C-N 3.33Å; I94-V96 PolarHBondContact O-N 3.31Å; V96-M98 VanDerWaalsContact C-N 3.35Å; V96-M98 PolarHBondContact O-N 3.23Å; V96-A99 PolarHBondContact O-N 2.87Å; V96-V100 PolarHBondContact O-N 3.16Å; V96-A118 HydrophobicContact CB-CB 3.85Å; V96-A118 HydrophobicContact CG1-CB 3.74Å; V96-P377 HydrophobicContact CG2-CB 3.95Å; V96-P377 HydrophobicContact CG2-CG 3.84Å; V96-Y380 HydrophobicContact CG1-CD2 4.33Å; V96-Y380 HydrophobicContact CG1-CE2 4.19Å; V96-Y380 HydrophobicContact CG2-CD2 3.8Å; V96-Y380 HydrophobicContact CG2-CE2 4.06Å; V96-Y387 HydrophobicContact CG1-CE1 4.31Å; V96-F391 HydrophobicContact CB-CZ 4.46Å; V96-F391 HydrophobicContact CG2-CZ 3.76Å
97	I	97.9	Very high	94.7	Very high	35 Å²	35	51.5 Å²	51.5	18%	0.179	27%	0.27	C	S	.	.	H	α-helix	trans	-59.2	-46.6	179.6	-65.8	163.3	0	0	0	110.5	N93 I94 A99 S101 M115 A118 I119 M122	N93-I97 VanDerWaalsContact O-CG1 3.31Å; N93-I97 WeakPolarHBondContact O-CG1 3.4Å; N93-I97 PolarHBondContact O-N 3.38Å; I94-I97 PolarHBondContact O-N 3.14Å; I97-A99 PolarHBondContact O-N 2.89Å; I97-S101 VanDerWaalsContact O-CB 3.25Å; I97-S101 WeakPolarHBondContact O-CB 3.05Å; I97-S101 PolarHBondContact O-N 2.88Å; I97-S101 PolarHBondContact O-OG 3.26Å; I97-M115 HydrophobicContact CG1-CG 4.33Å; I97-M115 HydrophobicContact CG2-CG 4.47Å; I97-A118 HydrophobicContact CG1-CB 4Å; I97-I119 HydrophobicContact CD1-CG1 3.73Å; I97-I119 HydrophobicContact CG1-CG1 4.1Å; I97-M122 HydrophobicContact CD1-CE 4.39Å; I97-M122 HydrophobicContact CD1-SD 3.96Å
98	M	95.8	Very high	94.2	Very high	55 Å²	55	50.5 Å²	50.5	27%	0.271	26%	0.261	S	S	.	.	H	α-helix	trans	-62.2	-43	176.3	-71.9	-167.3	-60.4	0	0	112.1	I94 L95 V96 S101 L102 Y394	I94-M98 HydrophobicContact CG2-CE 4.07Å; I94-M98 HydrophobicContact CG2-CG 4.41Å; I94-M98 HydrophobicContact CG2-SD 4.42Å; I94-M98 WeakPolarHBondContact O-CG 3.41Å; I94-M98 PolarHBondContact O-N 3.07Å; L95-M98 HydrophobicContact CD2-CE 3.69Å; L95-M98 HydrophobicContact CG-CE 4.45Å; L95-M98 PolarHBondContact O-N 3.43Å; V96-M98 VanDerWaalsContact C-N 3.35Å; V96-M98 PolarHBondContact O-N 3.23Å; M98-S101 PolarHBondContact O-N 3.49Å; M98-L102 HydrophobicContact CB-CD1 4.44Å; M98-L102 VanDerWaalsContact O-CB 3.31Å; M98-L102 WeakPolarHBondContact O-CB 2.99Å; M98-L102 VanDerWaalsContact O-CG 3.3Å; M98-L102 WeakPolarHBondContact O-CG 3.34Å; M98-L102 PolarHBondContact O-N 3.1Å; M98-Y394 HydrophobicContact CB-CD2 4.23Å; M98-Y394 HydrophobicContact CB-CE2 4.01Å; M98-Y394 HydrophobicContact CE-CD2 4.22Å; M98-Y394 HydrophobicContact CE-CG 4.42Å
99	A	95.3	Very high	93.6	Very high	0 Å²	0	46.2 Å²	46.2	0%	0	24%	0.24	C	C	.	.	H	α-helix	trans	-62.1	-47.7	179.8	0	0	0	0	0	112.2	L95 V96 I97 S101 E103 L106 Y387 A390 F391 Y394	L95-A99 WeakPolarHBondContact O-CB 3.41Å; L95-A99 PolarHBondContact O-N 3.48Å; V96-A99 PolarHBondContact O-N 2.87Å; I97-A99 PolarHBondContact O-N 2.89Å; A99-S101 VanDerWaalsContact C-N 3.31Å; A99-S101 PolarHBondContact O-N 3.26Å; A99-E103 WeakPolarHBondContact O-CB 3.26Å; A99-E103 VanDerWaalsContact O-CG 3.22Å; A99-E103 WeakPolarHBondContact O-CG 3.45Å; A99-E103 PolarHBondContact O-N 3.29Å; A99-L106 HydrophobicContact CB-CD1 4.06Å; A99-Y387 HydrophobicContact CB-CD1 3.73Å; A99-Y387 HydrophobicContact CB-CE1 3.8Å; A99-A390 HydrophobicContact CB-CB 4.17Å; A99-F391 HydrophobicContact CB-CD1 4.22Å; A99-F391 HydrophobicContact CB-CE1 3.71Å; A99-Y394 HydrophobicContact CB-CE2 4.04Å
100	V	95.3	Very high	93	Very high	1 Å²	1	47.1 Å²	47.1	1%	0.006	25%	0.246	C	C	.	.	H	α-helix	trans	-67.7	-35.1	179	-179.3	0	0	0	0	111.7	V96 Q107 N111 Y112 M115 Y387	V96-V100 PolarHBondContact O-N 3.16Å; V100-Q107 WeakPolarHBondContact O-CG 3.34Å; V100-N111 HydrophobicContact CG1-CB 4.17Å; V100-N111 HydrophobicContact CG2-CB 4.2Å; V100-Y112 HydrophobicContact CG1-CD1 4.15Å; V100-Y112 HydrophobicContact CG1-CE1 4.43Å; V100-M115 HydrophobicContact CB-CB 4.03Å; V100-M115 HydrophobicContact CB-CG 4.3Å; V100-M115 HydrophobicContact CB-SD 4.05Å; V100-M115 HydrophobicContact CG1-CB 3.97Å; V100-M115 HydrophobicContact CG1-CG 4.44Å; V100-M115 HydrophobicContact CG1-SD 3.91Å; V100-M115 HydrophobicContact CG2-CB 4.18Å; V100-Y387 HydrophobicContact CG2-CE1 4.1Å; V100-Y387 WeakPolarHBondContact CG2-OH 3.21Å
101	S	93.8	Very high	92.7	Very high	61 Å²	61	45.8 Å²	45.8	43%	0.427	24%	0.239	S	C	.	.	H	α-helix	trans	-70.9	-42	-179	-60	0	0	0	0	112.8	I97 M98 A99 Q107	I97-S101 VanDerWaalsContact O-CB 3.25Å; I97-S101 WeakPolarHBondContact O-CB 3.05Å; I97-S101 PolarHBondContact O-N 2.88Å; I97-S101 PolarHBondContact O-OG 3.26Å; M98-S101 PolarHBondContact O-N 3.49Å; A99-S101 VanDerWaalsContact C-N 3.31Å; A99-S101 PolarHBondContact O-N 3.26Å; S101-Q107 PolarHBondContact O-NE2 3.2Å; S101-Q107 VanDerWaalsContact O-NE2 3.13Å
102	L	91.8	Very high	92.5	Very high	102 Å²	102	44.2 Å²	44.2	53%	0.534	22%	0.223	S	C	.	.	H	α-helix	trans	-93.7	-34.2	-172.2	-61.1	175	0	0	0	113.4	M98 K104 Y394	M98-L102 HydrophobicContact CB-CD1 4.44Å; M98-L102 VanDerWaalsContact O-CB 3.31Å; M98-L102 WeakPolarHBondContact O-CB 2.99Å; M98-L102 VanDerWaalsContact O-CG 3.3Å; M98-L102 WeakPolarHBondContact O-CG 3.34Å; M98-L102 PolarHBondContact O-N 3.1Å; L102-K104 PolarHBondContact O-N 2.75Å; L102-Y394 WeakPolarHBondContact CB-OH 3.48Å; L102-Y394 HydrophobicContact CD1-CE1 4.03Å
103	E	91.7	Very high	92.4	Very high	12 Å²	12	43.7 Å²	43.7	6%	0.056	22%	0.217	C	C	.	.			trans	-85.3	106.4	-175.5	-58.8	-72.2	178.6	0	0	111	A99 K105 L106 A390 R393 Y394	A99-E103 WeakPolarHBondContact O-CB 3.26Å; A99-E103 VanDerWaalsContact O-CG 3.22Å; A99-E103 WeakPolarHBondContact O-CG 3.45Å; A99-E103 PolarHBondContact O-N 3.29Å; E103-K105 PolarHBondContact O-N 3.46Å; E103-K105 VanDerWaalsContact O-N 3.08Å; E103-L106 HydrophobicContact CB-CB 4.1Å; E103-L106 HydrophobicContact CB-CD1 3.88Å; E103-L106 HydrophobicContact CB-CG 3.93Å; E103-L106 HydrophobicContact CG-CD1 4.09Å; E103-L106 PolarHBondContact O-N 3.13Å; E103-A390 HydrophobicContact CG-CB 3.99Å; E103-A390 VanDerWaalsContact OE1-CB 3.27Å; E103-A390 WeakPolarHBondContact OE1-CB 3.34Å; E103-R393 IonicContact OE1-CZ 2.64Å; E103-R393 IonicContact OE1-NH2 2.58Å; E103-R393 PolarHBondContact OE1-NH2 3.37Å; E103-R393 IonicContact OE2-NH2 3.52Å; E103-Y394 PolarHBondContact OE1-OH 3.13Å
104	K	88.2	Confident	92.1	Very high	177 Å²	177	44.2 Å²	44.2	77%	0.77	22%	0.22	S	C	*	.	G	3₁₀ helix	trans	-55.2	-31.7	177	-65.3	-177.1	-179.2	179.8	0	113.1	L102 L106 Q107	L102-K104 PolarHBondContact O-N 2.75Å; K104-L106 PolarHBondContact O-N 3.27Å; K104-Q107 PolarHBondContact O-N 3.31Å
105	K	86.9	Confident	92.1	Very high	166 Å²	166	42.4 Å²	42.4	72%	0.722	21%	0.21	S	C	*	.	G	3₁₀ helix	trans	-66.3	-21.9	177	-68.6	179.1	-177.9	168.3	0	113.4	E103 T386	E103-K105 PolarHBondContact O-N 3.46Å; E103-K105 VanDerWaalsContact O-N 3.08Å; K105-T386 HydrophobicContact CB-CG2 4.35Å
106	L	88.1	Confident	92.1	Very high	5 Å²	5	41.3 Å²	41.3	3%	0.026	21%	0.205	C	C	.	.	G	3₁₀ helix	trans	-97.5	-2.4	179.2	-63.6	178	0	0	0	112.5	A99 E103 K104 N108 N111 T386 Y387	A99-L106 HydrophobicContact CB-CD1 4.06Å; E103-L106 HydrophobicContact CB-CB 4.1Å; E103-L106 HydrophobicContact CB-CD1 3.88Å; E103-L106 HydrophobicContact CB-CG 3.93Å; E103-L106 HydrophobicContact CG-CD1 4.09Å; E103-L106 PolarHBondContact O-N 3.13Å; K104-L106 PolarHBondContact O-N 3.27Å; L106-N108 VanDerWaalsContact C-N 3.25Å; L106-N108 PolarHBondContact O-N 2.91Å; L106-N111 WeakPolarHBondContact CA-ND2 3.29Å; L106-N111 WeakPolarHBondContact O-CB 3.43Å; L106-N111 VanDerWaalsContact O-CG 3.28Å; L106-N111 PolarHBondContact O-ND2 3.01Å; L106-T386 HydrophobicContact CD1-CG2 4.09Å; L106-T386 HydrophobicContact CD2-CG2 3.84Å; L106-T386 HydrophobicContact CG-CG2 3.8Å; L106-Y387 HydrophobicContact CD1-CD1 3.98Å; L106-Y387 HydrophobicContact CD1-CD2 4.34Å; L106-Y387 HydrophobicContact CD1-CE1 3.84Å; L106-Y387 HydrophobicContact CD1-CE2 4.2Å; L106-Y387 HydrophobicContact CD1-CG 4.23Å; L106-Y387 HydrophobicContact CD2-CD2 4.27Å; L106-Y387 HydrophobicContact CD2-CE2 3.98Å
107	Q	88.5	Confident	92.1	Very high	82 Å²	82	41.3 Å²	41.3	38%	0.383	21%	0.205	S	C	.	.			trans	-80.7	66.3	-178.6	-67.9	179.6	-5.7	0	0	112.5	V100 S101 K104	V100-Q107 WeakPolarHBondContact O-CG 3.34Å; S101-Q107 PolarHBondContact O-NE2 3.2Å; S101-Q107 VanDerWaalsContact O-NE2 3.13Å; K104-Q107 PolarHBondContact O-N 3.31Å
108	N	85.6	Confident	92.1	Very high	67 Å²	67	39.7 Å²	39.7	36%	0.358	20%	0.197	S	C	.	.	S	Bend	trans	-119.7	165.8	173.7	68.1	31.8	0	0	0	110.9	L106 T110 N111 Y112	L106-N108 VanDerWaalsContact C-N 3.25Å; L106-N108 PolarHBondContact O-N 2.91Å; N108-T110 VanDerWaalsContact C-N 3.35Å; N108-T110 PolarHBondContact O-N 3.43Å; N108-T110 PolarHBondContact OD1-N 3.04Å; N108-N111 PolarHBondContact ND2-ND2 3.46Å; N108-N111 VanDerWaalsContact ND2-ND2 3.17Å; N108-N111 PolarHBondContact O-N 3.11Å; N108-N111 VanDerWaalsContact OD1-CB 3.25Å; N108-N111 WeakPolarHBondContact OD1-CB 3.47Å; N108-N111 VanDerWaalsContact OD1-CG 3.26Å; N108-N111 PolarHBondContact OD1-N 3.28Å; N108-N111 PolarHBondContact OD1-ND2 3.46Å; N108-N111 VanDerWaalsContact OD1-ND2 3.09Å; N108-Y112 VanDerWaalsContact O-CD2 3.25Å; N108-Y112 WeakPolarHBondContact O-CD2 3.24Å; N108-Y112 PolarHBondContact O-N 3.38Å; N108-Y112 VanDerWaalsContact O-N 3.08Å
109	A	85.1	Confident	92.2	Very high	10 Å²	10	39.9 Å²	39.9	8%	0.083	20%	0.199	C	C	.	.	H	α-helix	trans	-53.6	-48.1	-177.3	0	0	0	0	0	112.8	N111 Y112 F113 N188 A193	A109-N111 PolarHBondContact O-N 3.25Å; A109-Y112 WeakPolarHBondContact O-CB 3.49Å; A109-Y112 PolarHBondContact O-N 2.98Å; A109-Y112 VanDerWaalsContact O-N 3.16Å; A109-F113 VanDerWaalsContact O-CD2 3.29Å; A109-F113 WeakPolarHBondContact O-CD2 3.25Å; A109-F113 PolarHBondContact O-N 3.03Å; A109-N188 VanDerWaalsContact CB-OD1 3.29Å; A109-N188 WeakPolarHBondContact CB-OD1 3.35Å; A109-A193 HydrophobicContact CB-CB 3.97Å
110	T	86.1	Confident	92.3	Very high	19 Å²	19	39.9 Å²	39.9	12%	0.117	20%	0.199	C	C	.	.	H	α-helix	trans	-60.6	-43.4	-179.3	-50.4	0	0	0	0	112.5	N108 Y112 F113 L114 I170 R174	N108-T110 VanDerWaalsContact C-N 3.35Å; N108-T110 PolarHBondContact O-N 3.43Å; N108-T110 PolarHBondContact OD1-N 3.04Å; T110-Y112 VanDerWaalsContact C-N 3.31Å; T110-Y112 PolarHBondContact O-N 3.16Å; T110-F113 WeakPolarHBondContact O-CB 3.48Å; T110-F113 PolarHBondContact O-N 3.07Å; T110-F113 VanDerWaalsContact O-N 3.14Å; T110-L114 WeakPolarHBondContact O-CG 3.31Å; T110-L114 PolarHBondContact O-N 3.25Å; T110-I170 HydrophobicContact CG2-CG2 4.28Å; T110-R174 PolarHBondContact OG1-NE 3.43Å; T110-R174 PolarHBondContact OG1-NH2 3.33Å
111	N	91.1	Very high	92.5	Very high	11 Å²	11	40 Å²	40	6%	0.059	20%	0.199	C	C	.	.	H	α-helix	trans	-70.1	-27.1	178.6	-74.6	-38.9	0	0	0	112.4	V100 L106 N108 A109 F113 L114 M115 Y387	V100-N111 HydrophobicContact CG1-CB 4.17Å; V100-N111 HydrophobicContact CG2-CB 4.2Å; L106-N111 WeakPolarHBondContact CA-ND2 3.29Å; L106-N111 WeakPolarHBondContact O-CB 3.43Å; L106-N111 VanDerWaalsContact O-CG 3.28Å; L106-N111 PolarHBondContact O-ND2 3.01Å; N108-N111 PolarHBondContact ND2-ND2 3.46Å; N108-N111 VanDerWaalsContact ND2-ND2 3.17Å; N108-N111 PolarHBondContact O-N 3.11Å; N108-N111 VanDerWaalsContact OD1-CB 3.25Å; N108-N111 WeakPolarHBondContact OD1-CB 3.47Å; N108-N111 VanDerWaalsContact OD1-CG 3.26Å; N108-N111 PolarHBondContact OD1-N 3.28Å; N108-N111 PolarHBondContact OD1-ND2 3.46Å; N108-N111 VanDerWaalsContact OD1-ND2 3.09Å; A109-N111 PolarHBondContact O-N 3.25Å; N111-F113 VanDerWaalsContact C-N 3.32Å; N111-L114 PolarHBondContact O-N 3.05Å; N111-M115 WeakPolarHBondContact O-CB 3.49Å; N111-M115 PolarHBondContact O-N 2.85Å; N111-Y387 PolarHBondContact OD1-OH 2.9Å; N111-Y387 VanDerWaalsContact OD1-OH 3.09Å
112	Y	93.8	Very high	92.7	Very high	15 Å²	15	39.3 Å²	39.3	6%	0.059	19%	0.19	C	C	.	.	H	α-helix	trans	-65.1	-36.6	169.1	-68.1	-50.3	0	0	0	112	V100 N108 A109 T110 M115 S116 R190 F194	V100-Y112 HydrophobicContact CG1-CD1 4.15Å; V100-Y112 HydrophobicContact CG1-CE1 4.43Å; N108-Y112 VanDerWaalsContact O-CD2 3.25Å; N108-Y112 WeakPolarHBondContact O-CD2 3.24Å; N108-Y112 PolarHBondContact O-N 3.38Å; N108-Y112 VanDerWaalsContact O-N 3.08Å; A109-Y112 WeakPolarHBondContact O-CB 3.49Å; A109-Y112 PolarHBondContact O-N 2.98Å; A109-Y112 VanDerWaalsContact O-N 3.16Å; T110-Y112 VanDerWaalsContact C-N 3.31Å; T110-Y112 PolarHBondContact O-N 3.16Å; Y112-M115 HydrophobicContact CD1-CE 4.13Å; Y112-M115 PolarHBondContact O-N 3.42Å; Y112-S116 PolarHBondContact O-N 3Å; Y112-R190 HydrophobicContact CE2-CG 3.89Å; Y112-F194 HydrophobicContact CD1-CZ 4.41Å
113	F	94.3	Very high	93	Very high	1 Å²	1	36.7 Å²	36.7	0%	0.004	18%	0.176	C	C	.	.	H	α-helix	trans	-64.5	-42.3	169.9	-77	-86.6	0	0	0	111.9	A109 T110 N111 M115 S116 L117 A169 I170 K196 I197	A109-F113 VanDerWaalsContact O-CD2 3.29Å; A109-F113 WeakPolarHBondContact O-CD2 3.25Å; A109-F113 PolarHBondContact O-N 3.03Å; T110-F113 WeakPolarHBondContact O-CB 3.48Å; T110-F113 PolarHBondContact O-N 3.07Å; T110-F113 VanDerWaalsContact O-N 3.14Å; N111-F113 VanDerWaalsContact C-N 3.32Å; F113-M115 VanDerWaalsContact C-N 3.3Å; F113-M115 PolarHBondContact O-N 3.38Å; F113-S116 PolarHBondContact O-N 3.32Å; F113-L117 WeakPolarHBondContact O-CB 3.33Å; F113-L117 PolarHBondContact O-N 2.92Å; F113-A169 HydrophobicContact CD1-CB 4.31Å; F113-A169 HydrophobicContact CE1-CB 3.89Å; F113-I170 HydrophobicContact CB-CD1 3.87Å; F113-I170 HydrophobicContact CB-CG1 3.56Å; F113-I170 HydrophobicContact CD1-CG1 4.49Å; F113-I170 HydrophobicContact CG-CG1 4.1Å; F113-K196 HydrophobicContact CE1-CB 4.14Å; F113-K196 HydrophobicContact CE2-CD 4.29Å; F113-K196 HydrophobicContact CZ-CB 3.52Å; F113-K196 HydrophobicContact CZ-CD 3.78Å; F113-K196 HydrophobicContact CZ-CG 4.34Å; F113-I197 HydrophobicContact CD1-CG1 3.86Å; F113-I197 HydrophobicContact CE1-CG1 3.88Å; F113-I197 HydrophobicContact CG-CG1 4.27Å; F113-I197 HydrophobicContact CZ-CG1 4.32Å
114	L	93.6	Very high	93.3	Very high	11 Å²	11	36.1 Å²	36.1	6%	0.058	17%	0.174	C	C	.	.	H	α-helix	trans	-63	-36.3	175.8	-61.2	179.1	0	0	0	112.2	T110 N111 A118 I170 Y380	T110-L114 WeakPolarHBondContact O-CG 3.31Å; T110-L114 PolarHBondContact O-N 3.25Å; N111-L114 PolarHBondContact O-N 3.05Å; L114-A118 WeakPolarHBondContact O-CB 3.3Å; L114-A118 PolarHBondContact O-N 2.92Å; L114-I170 HydrophobicContact CD2-CD1 3.68Å; L114-Y380 HydrophobicContact CD1-CE1 4.48Å; L114-Y380 HydrophobicContact CD2-CE1 4.25Å; L114-Y380 WeakPolarHBondContact CD2-OH 3.21Å
115	M	96.5	Very high	93.8	Very high	30 Å²	30	27.7 Å²	27.7	15%	0.148	14%	0.137	C	C	.	.	H	α-helix	trans	-66.4	-42.7	173.9	-176	179.3	77.5	0	0	111.7	I97 V100 N111 Y112 F113 A118 I119	I97-M115 HydrophobicContact CG1-CG 4.33Å; I97-M115 HydrophobicContact CG2-CG 4.47Å; V100-M115 HydrophobicContact CB-CB 4.03Å; V100-M115 HydrophobicContact CB-CG 4.3Å; V100-M115 HydrophobicContact CB-SD 4.05Å; V100-M115 HydrophobicContact CG1-CB 3.97Å; V100-M115 HydrophobicContact CG1-CG 4.44Å; V100-M115 HydrophobicContact CG1-SD 3.91Å; V100-M115 HydrophobicContact CG2-CB 4.18Å; N111-M115 WeakPolarHBondContact O-CB 3.49Å; N111-M115 PolarHBondContact O-N 2.85Å; Y112-M115 HydrophobicContact CD1-CE 4.13Å; Y112-M115 PolarHBondContact O-N 3.42Å; F113-M115 VanDerWaalsContact C-N 3.3Å; F113-M115 PolarHBondContact O-N 3.38Å; M115-A118 PolarHBondContact O-N 3.05Å; M115-I119 WeakPolarHBondContact O-CG1 3.25Å; M115-I119 PolarHBondContact O-N 2.74Å
116	S	97.9	Very high	94.3	Very high	7 Å²	7	26.3 Å²	26.3	5%	0.049	13%	0.131	C	C	.	.	H	α-helix	trans	-65.9	-38.7	175.9	-172.6	0	0	0	0	112.2	Y112 F113 I119 A120 H166 I197 W201	Y112-S116 PolarHBondContact O-N 3Å; F113-S116 PolarHBondContact O-N 3.32Å; S116-I119 WeakPolarHBondContact O-CB 3.13Å; S116-I119 PolarHBondContact O-N 2.74Å; S116-A120 PolarHBondContact O-N 3.35Å; S116-H166 VanDerWaalsContact CB-NE2 3.33Å; S116-H166 WeakPolarHBondContact CB-NE2 3.48Å; S116-H166 PolarHBondContact OG-CE1 2.73Å; S116-H166 PolarHBondContact OG-NE2 3.45Å; S116-I197 VanDerWaalsContact OG-CG2 3.28Å; S116-I197 WeakPolarHBondContact OG-CG2 3.25Å; S116-W201 PolarHBondContact OG-NE1 3.42Å
117	L	96.7	Very high	94.8	Very high	1 Å²	1	29.1 Å²	29.1	1%	0.005	15%	0.146	C	C	.	.	H	α-helix	trans	-59	-46.6	170.5	175	62.5	0	0	0	111.2	F113 I119 A120 D121 H166 L167	F113-L117 WeakPolarHBondContact O-CB 3.33Å; F113-L117 PolarHBondContact O-N 2.92Å; L117-I119 VanDerWaalsContact C-N 3.26Å; L117-I119 PolarHBondContact O-N 3.16Å; L117-A120 WeakPolarHBondContact O-CB 3.25Å; L117-A120 PolarHBondContact O-N 2.89Å; L117-A120 VanDerWaalsContact O-N 3.11Å; L117-D121 PolarHBondContact O-N 3.49Å; L117-H166 HydrophobicContact CB-CB 4.16Å; L117-H166 HydrophobicContact CD1-CB 4.21Å; L117-L167 HydrophobicContact CD2-CD2 3.74Å; L117-L167 HydrophobicContact CD2-CG 4.39Å
118	A	97.9	Very high	95.3	Very high	1 Å²	1	25.2 Å²	25.2	1%	0.008	13%	0.128	C	C	.	.	H	α-helix	trans	-62.3	-32.5	176.4	0	0	0	0	0	112.8	N93 V96 I97 L114 M115 M122	N93-A118 HydrophobicContact CB-CB 4.05Å; N93-A118 WeakPolarHBondContact CB-O 3.49Å; N93-A118 WeakPolarHBondContact OD1-CA 3.5Å; N93-A118 WeakPolarHBondContact OD1-CB 3.22Å; V96-A118 HydrophobicContact CB-CB 3.85Å; V96-A118 HydrophobicContact CG1-CB 3.74Å; I97-A118 HydrophobicContact CG1-CB 4Å; L114-A118 WeakPolarHBondContact O-CB 3.3Å; L114-A118 PolarHBondContact O-N 2.92Å; M115-A118 PolarHBondContact O-N 3.05Å; A118-M122 WeakPolarHBondContact O-CB 3.41Å; A118-M122 PolarHBondContact O-N 2.93Å
119	I	98.5	Very high	95.8	Very high	59 Å²	59	22 Å²	22	30%	0.303	11%	0.111	S	C	.	.	H	α-helix	trans	-65.8	-45.4	172.6	-68.5	165.6	0	0	0	110.5	I97 M115 S116 L117 M122 L123	I97-I119 HydrophobicContact CD1-CG1 3.73Å; I97-I119 HydrophobicContact CG1-CG1 4.1Å; M115-I119 WeakPolarHBondContact O-CG1 3.25Å; M115-I119 PolarHBondContact O-N 2.74Å; S116-I119 WeakPolarHBondContact O-CB 3.13Å; S116-I119 PolarHBondContact O-N 2.74Å; L117-I119 VanDerWaalsContact C-N 3.26Å; L117-I119 PolarHBondContact O-N 3.16Å; I119-M122 PolarHBondContact O-N 3.36Å; I119-L123 HydrophobicContact CG2-CD1 3.89Å; I119-L123 HydrophobicContact CG2-CG 4.38Å; I119-L123 WeakPolarHBondContact O-CB 3.38Å; I119-L123 VanDerWaalsContact O-CG 3.25Å; I119-L123 WeakPolarHBondContact O-CG 3.48Å; I119-L123 PolarHBondContact O-N 3.02Å
120	A	98.2	Very high	96.4	Very high	0 Å²	0	23.6 Å²	23.6	0%	0	12%	0.12	C	C	.	.	H	α-helix	trans	-60.4	-47.8	176.3	0	0	0	0	0	111.7	S116 L117 M122 L123 L124 A162 W201	S116-A120 PolarHBondContact O-N 3.35Å; L117-A120 WeakPolarHBondContact O-CB 3.25Å; L117-A120 PolarHBondContact O-N 2.89Å; L117-A120 VanDerWaalsContact O-N 3.11Å; A120-M122 PolarHBondContact O-N 3.34Å; A120-L123 PolarHBondContact O-N 3.46Å; A120-L124 WeakPolarHBondContact O-CB 2.93Å; A120-L124 PolarHBondContact O-N 3Å; A120-A162 HydrophobicContact CB-CB 4.12Å; A120-W201 HydrophobicContact CB-CH2 3.91Å; A120-W201 HydrophobicContact CB-CZ2 4.03Å
121	D	98.1	Very high	96.9	Very high	2 Å²	2	24.2 Å²	24.2	1%	0.011	12%	0.124	C	C	.	.	H	α-helix	trans	-64	-37.8	178.2	-73.9	-23.6	0	0	0	112.5	T89 L117 G125 S163 S373 N376	T89-D121 WeakPolarHBondContact CG2-O 3.49Å; L117-D121 PolarHBondContact O-N 3.49Å; D121-G125 PolarHBondContact O-N 3.08Å; D121-S163 PolarHBondContact OD1-OG 3.28Å; D121-S373 WeakPolarHBondContact OD1-CB 3.33Å; D121-S373 PolarHBondContact OD1-OG 3.33Å; D121-N376 PolarHBondContact OD2-ND2 3.28Å
122	M	98.3	Very high	97.1	Very high	47 Å²	47	24 Å²	24	23%	0.232	12%	0.123	C	C	.	.	H	α-helix	trans	-66.3	-42.7	174.4	-176.8	-169.7	73.2	0	0	111.6	N93 I94 I97 A118 I119 A120 G125 F126	N93-M122 HydrophobicContact CB-CB 4.06Å; I94-M122 HydrophobicContact CD1-SD 4.41Å; I94-M122 HydrophobicContact CG1-CG 4.46Å; I94-M122 HydrophobicContact CG1-SD 3.69Å; I97-M122 HydrophobicContact CD1-CE 4.39Å; I97-M122 HydrophobicContact CD1-SD 3.96Å; A118-M122 WeakPolarHBondContact O-CB 3.41Å; A118-M122 PolarHBondContact O-N 2.93Å; I119-M122 PolarHBondContact O-N 3.36Å; A120-M122 PolarHBondContact O-N 3.34Å; M122-G125 PolarHBondContact O-N 2.58Å; M122-F126 WeakPolarHBondContact O-CB 3.28Å; M122-F126 PolarHBondContact O-N 2.74Å
123	L	98.4	Very high	97.1	Very high	48 Å²	48	25.2 Å²	25.2	25%	0.251	13%	0.13	S	C	.	.	H	α-helix	trans	-66.1	-38.6	177	-70.9	171.6	0	0	0	111.6	I119 A120 F126 L127 F159 W201	I119-L123 HydrophobicContact CG2-CD1 3.89Å; I119-L123 HydrophobicContact CG2-CG 4.38Å; I119-L123 WeakPolarHBondContact O-CB 3.38Å; I119-L123 VanDerWaalsContact O-CG 3.25Å; I119-L123 WeakPolarHBondContact O-CG 3.48Å; I119-L123 PolarHBondContact O-N 3.02Å; A120-L123 PolarHBondContact O-N 3.46Å; L123-F126 PolarHBondContact O-N 2.97Å; L123-L127 HydrophobicContact CD2-CD1 4.16Å; L123-L127 VanDerWaalsContact O-CB 3.31Å; L123-L127 WeakPolarHBondContact O-CB 3.47Å; L123-L127 PolarHBondContact O-N 3.09Å; L123-F159 HydrophobicContact CB-CD1 3.96Å; L123-F159 HydrophobicContact CB-CD2 4.11Å; L123-F159 HydrophobicContact CB-CE1 3.69Å; L123-F159 HydrophobicContact CB-CE2 3.83Å; L123-F159 HydrophobicContact CB-CG 4.19Å; L123-F159 HydrophobicContact CB-CZ 3.62Å; L123-F159 HydrophobicContact CD1-CD1 4.26Å; L123-F159 HydrophobicContact CD1-CE1 3.53Å; L123-F159 HydrophobicContact CD1-CZ 3.92Å; L123-F159 HydrophobicContact CG-CE1 4.23Å; L123-F159 HydrophobicContact CG-CZ 4.28Å; L123-W201 HydrophobicContact CD1-CH2 4.4Å
124	L	98.3	Very high	97.1	Very high	0 Å²	0	27.6 Å²	27.6	0%	0	14%	0.142	C	C	.	.	I	π-helix	trans	-58.3	-49.7	170.6	-174	74.5	0	0	0	110.8	A120 F126 V128 M129 F159 Y370 S373	A120-L124 WeakPolarHBondContact O-CB 2.93Å; A120-L124 PolarHBondContact O-N 3Å; L124-F126 VanDerWaalsContact C-N 3.29Å; L124-F126 PolarHBondContact O-N 2.81Å; L124-V128 HydrophobicContact CD1-CB 3.81Å; L124-V128 HydrophobicContact CD1-CG1 3.92Å; L124-V128 HydrophobicContact CD1-CG2 3.97Å; L124-V128 HydrophobicContact CG-CB 4.45Å; L124-V128 WeakPolarHBondContact O-CA 3.29Å; L124-V128 WeakPolarHBondContact O-CB 3.44Å; L124-V128 PolarHBondContact O-N 3.17Å; L124-M129 HydrophobicContact CD2-CE 3.8Å; L124-M129 HydrophobicContact CG-CE 3.99Å; L124-M129 PolarHBondContact O-N 2.87Å; L124-F159 HydrophobicContact CB-CB 4.03Å; L124-F159 HydrophobicContact CD1-CB 4.08Å; L124-Y370 HydrophobicContact CD1-CE1 4.2Å; L124-Y370 HydrophobicContact CD2-CD1 4.05Å; L124-Y370 HydrophobicContact CD2-CE1 4.47Å; L124-Y370 HydrophobicContact CG-CD1 4.49Å; L124-S373 WeakPolarHBondContact CD2-OG 3.01Å
125	G	98	Very high	97	Very high	0 Å²	0	27.7 Å²	27.7	0%	0	14%	0.143	C	C	.	.	I	π-helix	trans	-64.1	-29.5	178.5	0	0	0	0	0	114.5	D121 M122 P130	D121-G125 PolarHBondContact O-N 3.08Å; M122-G125 PolarHBondContact O-N 2.58Å; G125-P130 VanDerWaalsContact O-CD 3.26Å; G125-P130 WeakPolarHBondContact O-CD 3.22Å; G125-P130 WeakPolarHBondContact O-CG 3.33Å
126	F	98.1	Very high	96.7	Very high	136 Å²	136	27.6 Å²	27.6	60%	0.596	14%	0.143	S	C	*	.	I	π-helix	trans	-91.8	-36.9	-177.5	-172.6	-103.2	0	0	0	113.7	I90 M122 L123 L124 P130	I90-F126 HydrophobicContact CD1-CB 4.36Å; I90-F126 HydrophobicContact CD1-CD2 4.24Å; M122-F126 WeakPolarHBondContact O-CB 3.28Å; M122-F126 PolarHBondContact O-N 2.74Å; L123-F126 PolarHBondContact O-N 2.97Å; L124-F126 VanDerWaalsContact C-N 3.29Å; L124-F126 PolarHBondContact O-N 2.81Å; F126-P130 WeakPolarHBondContact O-CG 3.39Å
127	L	98	Very high	96.4	Very high	65 Å²	65	31.2 Å²	31.2	34%	0.34	16%	0.161	S	C	.	.	I	π-helix	trans	-103.1	-32.7	-172.9	-60.7	175.4	0	0	0	113.3	L123 V131 L155 F159	L123-L127 HydrophobicContact CD2-CD1 4.16Å; L123-L127 VanDerWaalsContact O-CB 3.31Å; L123-L127 WeakPolarHBondContact O-CB 3.47Å; L123-L127 PolarHBondContact O-N 3.09Å; L127-V131 WeakPolarHBondContact O-CG2 3.44Å; L127-L155 HydrophobicContact CB-CD1 4.48Å; L127-L155 HydrophobicContact CD1-CD1 4.5Å; L127-F159 HydrophobicContact CB-CE2 4.45Å; L127-F159 HydrophobicContact CD1-CE2 3.84Å; L127-F159 HydrophobicContact CD1-CZ 4Å
128	V	98.3	Very high	96.1	Very high	0 Å²	0	37.6 Å²	37.6	0%	0	19%	0.186	C	C	.	.	I	π-helix	trans	-102.4	-52.8	-169.8	176.5	0	0	0	0	111.1	L124 V131 S132 W152 L155 D156 F159 Y370	L124-V128 HydrophobicContact CD1-CB 3.81Å; L124-V128 HydrophobicContact CD1-CG1 3.92Å; L124-V128 HydrophobicContact CD1-CG2 3.97Å; L124-V128 HydrophobicContact CG-CB 4.45Å; L124-V128 WeakPolarHBondContact O-CA 3.29Å; L124-V128 WeakPolarHBondContact O-CB 3.44Å; L124-V128 PolarHBondContact O-N 3.17Å; V128-V131 PolarHBondContact O-N 3.08Å; V128-S132 PolarHBondContact O-N 3.42Å; V128-W152 PolarHBondContact O-NE1 2.87Å; V128-W152 VanDerWaalsContact O-NE1 3.16Å; V128-L155 HydrophobicContact CG2-CB 4Å; V128-D156 HydrophobicContact CG1-CB 3.62Å; V128-D156 HydrophobicContact CG2-CB 4.27Å; V128-F159 HydrophobicContact CG2-CD2 4.11Å; V128-Y370 HydrophobicContact CG1-CE1 4.38Å; V128-Y370 WeakPolarHBondContact CG1-OH 3.48Å
129	M	97.5	Very high	95.6	Very high	0 Å²	0	40 Å²	40	0%	0	21%	0.212	C	C	.	.	H	α-helix	trans	-60.4	-39.3	-176.7	-61.7	-174.7	-166.7	0	0	113.8	V85 I86 T89 L124 V131 S132 M133 W367 Y370	V85-M129 HydrophobicContact CG1-SD 4.42Å; I86-M129 HydrophobicContact CD1-CB 4.1Å; I86-M129 HydrophobicContact CG1-CB 3.6Å; I86-M129 HydrophobicContact CG1-SD 4.28Å; T89-M129 HydrophobicContact CG2-CE 3.91Å; T89-M129 HydrophobicContact CG2-SD 4.49Å; L124-M129 HydrophobicContact CD2-CE 3.8Å; L124-M129 HydrophobicContact CG-CE 3.99Å; L124-M129 PolarHBondContact O-N 2.87Å; M129-V131 VanDerWaalsContact C-N 3.34Å; M129-V131 PolarHBondContact O-N 3.44Å; M129-S132 WeakPolarHBondContact O-CB 3.49Å; M129-S132 PolarHBondContact O-N 3.25Å; M129-M133 PolarHBondContact O-N 3.24Å; M129-W367 HydrophobicContact CB-CH2 4.18Å; M129-W367 HydrophobicContact CB-CZ3 4.32Å; M129-Y370 HydrophobicContact CE-CD1 4.33Å; M129-Y370 HydrophobicContact CE-CG 4.01Å; M129-Y370 WeakPolarHBondContact CE-O 3.34Å; M129-Y370 HydrophobicContact CG-CD2 3.93Å; M129-Y370 HydrophobicContact CG-CE2 4.36Å; M129-Y370 HydrophobicContact CG-CG 4.06Å; M129-Y370 HydrophobicContact SD-CG 4.43Å
130	P	97.1	Very high	95.2	Very high	43 Å²	43	41.5 Å²	41.5	28%	0.279	21%	0.214	S	C	.	.	H	α-helix	trans	-68.4	-34.3	178.6	-23	37.3	0	0	0	112.6	I86 G125 F126 M133 L134	I86-P130 HydrophobicContact CD1-CG 4.31Å; I86-P130 HydrophobicContact CG2-CG 4.42Å; G125-P130 VanDerWaalsContact O-CD 3.26Å; G125-P130 WeakPolarHBondContact O-CD 3.22Å; G125-P130 WeakPolarHBondContact O-CG 3.33Å; F126-P130 WeakPolarHBondContact O-CG 3.39Å; P130-M133 PolarHBondContact O-N 3.14Å; P130-L134 PolarHBondContact O-N 3.16Å
131	V	96.4	Very high	94.9	Very high	32 Å²	32	44.7 Å²	44.7	19%	0.194	23%	0.234	C	C	.	.	H	α-helix	trans	-70	-38.8	174.2	178.9	0	0	0	0	110.3	L127 V128 M129 M133 L134 T135 W142 L144 W152	L127-V131 WeakPolarHBondContact O-CG2 3.44Å; V128-V131 PolarHBondContact O-N 3.08Å; M129-V131 VanDerWaalsContact C-N 3.34Å; M129-V131 PolarHBondContact O-N 3.44Å; V131-M133 VanDerWaalsContact C-N 3.35Å; V131-M133 PolarHBondContact O-N 3.37Å; V131-L134 WeakPolarHBondContact O-CB 3.47Å; V131-L134 PolarHBondContact O-N 2.86Å; V131-T135 PolarHBondContact O-N 3.15Å; V131-W142 HydrophobicContact CG1-CH2 3.68Å; V131-W142 HydrophobicContact CG1-CZ3 3.73Å; V131-L144 HydrophobicContact CG1-CD1 4.17Å; V131-W152 HydrophobicContact CB-CG 4.36Å; V131-W152 HydrophobicContact CG1-CB 4.5Å; V131-W152 VanDerWaalsContact CG1-CD1 3.45Å; V131-W152 HydrophobicContact CG1-CD2 4.18Å; V131-W152 HydrophobicContact CG1-CG 3.79Å
132	S	95	Very high	94.8	Very high	7 Å²	7	45.9 Å²	45.9	5%	0.049	24%	0.238	C	C	.	.	H	α-helix	trans	-62.5	-39.6	171.5	-174.1	0	0	0	0	112.4	V128 M129 L134 T135 I136	V128-S132 PolarHBondContact O-N 3.42Å; M129-S132 WeakPolarHBondContact O-CB 3.49Å; M129-S132 PolarHBondContact O-N 3.25Å; S132-L134 VanDerWaalsContact C-N 3.33Å; S132-L134 PolarHBondContact O-N 3.46Å; S132-T135 PolarHBondContact O-N 2.99Å; S132-T135 PolarHBondContact O-OG1 2.82Å; S132-I136 WeakPolarHBondContact O-CG1 3.21Å; S132-I136 PolarHBondContact O-N 3.33Å
133	M	94.8	Very high	94.6	Very high	40 Å²	40	46 Å²	46	20%	0.197	24%	0.243	C	C	.	.	H	α-helix	trans	-63.7	-40.5	172.7	178.8	-168.5	77.8	0	0	111.3	T82 V83 I86 M129 P130 V131 T135 I136 L137 W367	T82-M133 WeakPolarHBondContact OG1-CG 3.48Å; V83-M133 HydrophobicContact CG2-SD 3.42Å; V83-M133 WeakPolarHBondContact CG2-SD 3.3Å; I86-M133 HydrophobicContact CD1-CB 4.35Å; I86-M133 HydrophobicContact CD1-SD 4.25Å; M129-M133 PolarHBondContact O-N 3.24Å; P130-M133 PolarHBondContact O-N 3.14Å; V131-M133 VanDerWaalsContact C-N 3.35Å; V131-M133 PolarHBondContact O-N 3.37Å; M133-T135 VanDerWaalsContact C-N 3.33Å; M133-T135 PolarHBondContact O-N 3.39Å; M133-I136 WeakPolarHBondContact O-CB 3.39Å; M133-I136 PolarHBondContact O-N 3Å; M133-L137 WeakPolarHBondContact O-CG 3.4Å; M133-L137 PolarHBondContact O-N 3.36Å; M133-L137 VanDerWaalsContact O-N 3.11Å; M133-W367 HydrophobicContact CB-CH2 4.35Å; M133-W367 HydrophobicContact CB-CZ2 4.38Å
134	L	93.4	Very high	94.4	Very high	50 Å²	50	46.6 Å²	46.6	26%	0.262	25%	0.246	S	C	.	.	H	α-helix	trans	-60.1	-42.4	176.2	-177.3	66.6	0	0	0	111.4	P130 V131 S132 I136 L137 Y138 P143 L144	P130-L134 PolarHBondContact O-N 3.16Å; V131-L134 WeakPolarHBondContact O-CB 3.47Å; V131-L134 PolarHBondContact O-N 2.86Å; S132-L134 VanDerWaalsContact C-N 3.33Å; S132-L134 PolarHBondContact O-N 3.46Å; L134-I136 VanDerWaalsContact C-N 3.33Å; L134-I136 PolarHBondContact O-N 2.95Å; L134-L137 PolarHBondContact O-N 3.19Å; L134-Y138 HydrophobicContact CD1-CD2 3.88Å; L134-Y138 HydrophobicContact CD1-CE2 3.59Å; L134-Y138 HydrophobicContact CG-CD2 4.3Å; L134-Y138 HydrophobicContact CG-CE2 4.38Å; L134-Y138 WeakPolarHBondContact O-CD2 3.47Å; L134-Y138 PolarHBondContact O-N 3.38Å; L134-P143 HydrophobicContact CD2-CG 3.97Å; L134-P143 HydrophobicContact CG-CG 3.98Å; L134-L144 HydrophobicContact CD2-CD1 4.21Å; L134-L144 HydrophobicContact CD2-CD2 4.31Å; L134-L144 HydrophobicContact CD2-CG 4.19Å
135	T	91.4	Very high	94.3	Very high	14 Å²	14	50.7 Å²	50.7	9%	0.086	27%	0.272	C	S	.	.	H	α-helix	trans	-64.6	-36.7	177.1	60.6	0	0	0	0	112	V131 S132 M133 L137 Y138 G139 Y140 W142	V131-T135 PolarHBondContact O-N 3.15Å; S132-T135 PolarHBondContact O-N 2.99Å; S132-T135 PolarHBondContact O-OG1 2.82Å; M133-T135 VanDerWaalsContact C-N 3.33Å; M133-T135 PolarHBondContact O-N 3.39Å; T135-L137 VanDerWaalsContact C-N 3.33Å; T135-L137 PolarHBondContact O-N 3.31Å; T135-Y138 CarbonylContact O-C 3.53Å; T135-Y138 PolarHBondContact O-N 3.03Å; T135-G139 PolarHBondContact O-N 3.18Å; T135-Y140 VanDerWaalsContact O-CA 3.25Å; T135-Y140 WeakPolarHBondContact O-CA 3.46Å; T135-Y140 PolarHBondContact O-N 2.93Å; T135-W142 HydrophobicContact CG2-CE3 3.7Å; T135-W142 HydrophobicContact CG2-CZ3 3.91Å
136	I	90.6	Very high	94	Very high	28 Å²	28	54.1 Å²	54.1	14%	0.144	29%	0.293	C	S	.	.	H	α-helix	trans	-60.3	-42.9	173.3	-64.1	163.4	0	0	0	111.3	T82 S132 M133 L134 Y138 G139 Y140 W367	T82-I136 HydrophobicContact CG2-CD1 4.15Å; S132-I136 WeakPolarHBondContact O-CG1 3.21Å; S132-I136 PolarHBondContact O-N 3.33Å; M133-I136 WeakPolarHBondContact O-CB 3.39Å; M133-I136 PolarHBondContact O-N 3Å; L134-I136 VanDerWaalsContact C-N 3.33Å; L134-I136 PolarHBondContact O-N 2.95Å; I136-Y138 PolarHBondContact O-N 2.98Å; I136-G139 PolarHBondContact O-N 3.47Å; I136-G139 VanDerWaalsContact O-N 3.13Å; I136-Y140 HydrophobicContact CG1-CE1 3.74Å; I136-W367 HydrophobicContact CD1-CZ2 3.78Å
137	L	90.5	Very high	93.8	Very high	82 Å²	82	51.9 Å²	51.9	43%	0.429	28%	0.283	S	S	.	.	H	α-helix	trans	-64.5	-28.8	179.7	-69.4	174.6	0	0	0	113	A79 M133 L134 T135 G139	A79-L137 HydrophobicContact CB-CD2 3.72Å; M133-L137 WeakPolarHBondContact O-CG 3.4Å; M133-L137 PolarHBondContact O-N 3.36Å; M133-L137 VanDerWaalsContact O-N 3.11Å; L134-L137 PolarHBondContact O-N 3.19Å; T135-L137 VanDerWaalsContact C-N 3.33Å; T135-L137 PolarHBondContact O-N 3.31Å; L137-G139 VanDerWaalsContact C-N 3.33Å
138	Y	90.7	Very high	93.7	Very high	135 Å²	135	52.6 Å²	52.6	53%	0.529	29%	0.287	S	S	.	.	T	Hydrogen-bonded Turn	trans	-95	20.7	176.4	-78.9	-99.1	0	0	0	112.8	L134 T135 I136 Y140 T141 P143	L134-Y138 HydrophobicContact CD1-CD2 3.88Å; L134-Y138 HydrophobicContact CD1-CE2 3.59Å; L134-Y138 HydrophobicContact CG-CD2 4.3Å; L134-Y138 HydrophobicContact CG-CE2 4.38Å; L134-Y138 WeakPolarHBondContact O-CD2 3.47Å; L134-Y138 PolarHBondContact O-N 3.38Å; T135-Y138 CarbonylContact O-C 3.53Å; T135-Y138 PolarHBondContact O-N 3.03Å; I136-Y138 PolarHBondContact O-N 2.98Å; Y138-Y140 VanDerWaalsContact C-N 3.32Å; Y138-Y140 PolarHBondContact O-N 3.14Å; Y138-T141 PolarHBondContact O-N 3.38Å; Y138-T141 PolarHBondContact O-OG1 3.05Å; Y138-P143 HydrophobicContact CD1-CB 3.77Å; Y138-P143 HydrophobicContact CD1-CG 4.4Å; Y138-P143 HydrophobicContact CD2-CB 4.15Å; Y138-P143 HydrophobicContact CD2-CG 3.94Å; Y138-P143 HydrophobicContact CE1-CB 3.9Å; Y138-P143 HydrophobicContact CE2-CB 4.27Å; Y138-P143 HydrophobicContact CE2-CG 4.28Å; Y138-P143 HydrophobicContact CG-CB 3.89Å; Y138-P143 HydrophobicContact CG-CG 4Å
139	G	88.4	Confident	93.6	Very high	53 Å²	53	52.6 Å²	52.6	55%	0.546	29%	0.287	S	S	.	.	T	Hydrogen-bonded Turn	trans	63.8	35.9	177.5	0	0	0	0	0	113.5	T135 I136 L137 T141	T135-G139 PolarHBondContact O-N 3.18Å; I136-G139 PolarHBondContact O-N 3.47Å; I136-G139 VanDerWaalsContact O-N 3.13Å; L137-G139 VanDerWaalsContact C-N 3.33Å; G139-T141 PolarHBondContact O-N 3.19Å
140	Y	89.8	Confident	93.5	Very high	89 Å²	89	52.7 Å²	52.7	35%	0.349	29%	0.287	S	S	.	.	T	Hydrogen-bonded Turn	trans	63.6	11.5	-176.2	-55.3	-82.6	0	0	0	115.7	T135 I136 Y138 S227 N363	T135-Y140 VanDerWaalsContact O-CA 3.25Å; T135-Y140 WeakPolarHBondContact O-CA 3.46Å; T135-Y140 PolarHBondContact O-N 2.93Å; I136-Y140 HydrophobicContact CG1-CE1 3.74Å; Y138-Y140 VanDerWaalsContact C-N 3.32Å; Y138-Y140 PolarHBondContact O-N 3.14Å; Y140-S227 WeakPolarHBondContact O-CA 3.32Å; Y140-S227 WeakPolarHBondContact O-CB 2.99Å; Y140-S227 PolarHBondContact O-OG 2.92Å; Y140-N363 HydrophobicContact CE1-CB 4.06Å; Y140-N363 VanDerWaalsContact CE1-CG 3.4Å; Y140-N363 WeakPolarHBondContact CE1-ND2 3.32Å; Y140-N363 WeakPolarHBondContact CE1-OD1 3.46Å; Y140-N363 VanDerWaalsContact CZ-ND2 3.32Å
141	T	92	Very high	93.4	Very high	67 Å²	67	53.4 Å²	53.4	41%	0.411	29%	0.291	S	S	.	.			trans	-80.6	143	166.1	66	0	0	0	0	109.8	Y138 G139 P143	Y138-T141 PolarHBondContact O-N 3.38Å; Y138-T141 PolarHBondContact O-OG1 3.05Å; G139-T141 PolarHBondContact O-N 3.19Å; T141-P143 VanDerWaalsContact O-CD 3.23Å; T141-P143 WeakPolarHBondContact O-CD 3.37Å
142	W	95.1	Very high	93.5	Very high	27 Å²	27	53.3 Å²	53.3	10%	0.102	29%	0.287	C	S	.	.			trans	-82.7	111.2	-179.4	-177.5	-104.3	0	0	0	111.2	V131 T135 L144 P145 L148 C149 W152 F223 D226 C228	V131-W142 HydrophobicContact CG1-CH2 3.68Å; V131-W142 HydrophobicContact CG1-CZ3 3.73Å; T135-W142 HydrophobicContact CG2-CE3 3.7Å; T135-W142 HydrophobicContact CG2-CZ3 3.91Å; W142-L144 HydrophobicContact CD2-CB 4.48Å; W142-L144 HydrophobicContact CH2-CD1 3.99Å; W142-L144 HydrophobicContact CZ2-CB 3.66Å; W142-L144 HydrophobicContact CZ2-CD1 3.91Å; W142-L144 HydrophobicContact CZ2-CG 4.34Å; W142-L144 PolarHBondContact NE1-O 2.91Å; W142-P145 PolarHBondContact NE1-O 3.23Å; W142-L148 VanDerWaalsContact CZ2-C 3.45Å; W142-L148 HydrophobicContact CZ2-CB 3.91Å; W142-C149 HydrophobicContact CD2-CB 4.15Å; W142-C149 VanDerWaalsContact CZ2-CA 3.43Å; W142-C149 HydrophobicContact CZ2-CB 3.94Å; W142-C149 VanDerWaalsContact CZ2-N 3.28Å; W142-W152 HydrophobicContact CH2-CB 3.82Å; W142-W152 HydrophobicContact CH2-CD2 4.29Å; W142-W152 HydrophobicContact CH2-CE3 4.36Å; W142-W152 HydrophobicContact CH2-CG 4.08Å; W142-W152 HydrophobicContact CZ3-CB 4.49Å; W142-W152 HydrophobicContact CZ3-CD2 4.09Å; W142-W152 AromaticContact CZ3-CE3 3.95Å; W142-W152 HydrophobicContact CZ3-CE3 3.95Å; W142-W152 HydrophobicContact CZ3-CG 4.34Å; W142-F223 HydrophobicContact CB-CE1 3.79Å; W142-F223 AromaticContact CD1-CE1 3.79Å; W142-F223 AromaticContact CD1-CZ 3.74Å; W142-F223 AromaticContact CG-CE1 3.83Å; W142-F223 HydrophobicContact CG-CE1 3.83Å; W142-F223 HydrophobicContact CG-CZ 4.18Å; W142-D226 PolarHBondContact N-O 2.76Å; W142-C228 HydrophobicContact CB-CB 4.01Å; W142-C228 HydrophobicContact CD2-CB 3.56Å; W142-C228 HydrophobicContact CE3-CB 3.25Å; W142-C228 HydrophobicContact CG-CB 3.9Å; W142-C228 HydrophobicContact CZ3-CB 3.92Å
143	P	94.3	Very high	93.6	Very high	51 Å²	51	53.5 Å²	53.5	33%	0.331	29%	0.287	S	S	.	.			trans	-90.2	-9.3	-173.9	35.8	-33.5	0	0	0	113.5	L134 Y138 T141	L134-P143 HydrophobicContact CD2-CG 3.97Å; L134-P143 HydrophobicContact CG-CG 3.98Å; Y138-P143 HydrophobicContact CD1-CB 3.77Å; Y138-P143 HydrophobicContact CD1-CG 4.4Å; Y138-P143 HydrophobicContact CD2-CB 4.15Å; Y138-P143 HydrophobicContact CD2-CG 3.94Å; Y138-P143 HydrophobicContact CE1-CB 3.9Å; Y138-P143 HydrophobicContact CE2-CB 4.27Å; Y138-P143 HydrophobicContact CE2-CG 4.28Å; Y138-P143 HydrophobicContact CG-CB 3.89Å; Y138-P143 HydrophobicContact CG-CG 4Å; T141-P143 VanDerWaalsContact O-CD 3.23Å; T141-P143 WeakPolarHBondContact O-CD 3.37Å
144	L	95.4	Very high	93.7	Very high	60 Å²	60	53.6 Å²	53.6	31%	0.314	29%	0.286	S	S	.	.	S	Bend	trans	-93.8	167.8	-175.1	-66.3	175.3	0	0	0	111.3	V131 L134 W142 L148	V131-L144 HydrophobicContact CG1-CD1 4.17Å; L134-L144 HydrophobicContact CD2-CD1 4.21Å; L134-L144 HydrophobicContact CD2-CD2 4.31Å; L134-L144 HydrophobicContact CD2-CG 4.19Å; W142-L144 HydrophobicContact CD2-CB 4.48Å; W142-L144 HydrophobicContact CH2-CD1 3.99Å; W142-L144 HydrophobicContact CZ2-CB 3.66Å; W142-L144 HydrophobicContact CZ2-CD1 3.91Å; W142-L144 HydrophobicContact CZ2-CG 4.34Å; W142-L144 PolarHBondContact NE1-O 2.91Å; L144-L148 HydrophobicContact CB-CD1 4.36Å
145	P	95.4	Very high	93.9	Very high	85 Å²	85	53.1 Å²	53.1	55%	0.552	28%	0.283	S	S	*	.			trans	-49.7	143.6	171.2	-29.8	32.8	0	0	0	113.4	W142 K147 L148	W142-P145 PolarHBondContact NE1-O 3.23Å; P145-K147 VanDerWaalsContact C-N 3.29Å; P145-K147 PolarHBondContact O-N 3.49Å; P145-L148 HydrophobicContact CB-CD1 4.45Å; P145-L148 HydrophobicContact CB-CG 4.35Å; P145-L148 HydrophobicContact CG-CD1 4.23Å; P145-L148 WeakPolarHBondContact O-CB 3.37Å; P145-L148 PolarHBondContact O-N 3.45Å
146	T	92.4	Very high	94.2	Very high	72 Å²	72	53.7 Å²	53.7	44%	0.442	29%	0.286	S	S	.	.	H	α-helix	trans	-56.5	-41	-174.8	53.7	0	0	0	0	112.9	L148 C149 F223	T146-L148 PolarHBondContact O-N 3Å; T146-C149 VanDerWaalsContact O-CB 3.3Å; T146-C149 WeakPolarHBondContact O-CB 3.4Å; T146-C149 PolarHBondContact O-N 3.36Å; T146-C149 VanDerWaalsContact O-N 3.08Å; T146-F223 HydrophobicContact CG2-CE2 4.38Å; T146-F223 HydrophobicContact CG2-CZ 4.4Å
147	K	93	Very high	94.5	Very high	90 Å²	90	54.1 Å²	54.1	39%	0.391	29%	0.29	S	S	.	.	H	α-helix	trans	-65.5	-24.8	179.3	-57.9	-55.9	174.6	-165.8	0	113.7	P145 C149 V151 L216 D219	P145-K147 VanDerWaalsContact C-N 3.29Å; P145-K147 PolarHBondContact O-N 3.49Å; K147-C149 VanDerWaalsContact C-N 3.27Å; K147-C149 PolarHBondContact O-N 2.67Å; K147-V151 WeakPolarHBondContact O-CG2 3.35Å; K147-L216 HydrophobicContact CB-CD2 4Å; K147-L216 HydrophobicContact CD-CD2 3.76Å; K147-L216 HydrophobicContact CG-CD2 4.41Å; K147-L216 PolarHBondContact NZ-O 3.11Å; K147-D219 IonicContact NZ-OD1 3.9Å; K147-D219 PolarHBondContact NZ-OD1 2.95Å; K147-D219 IonicContact NZ-OD2 2.76Å
148	L	95.5	Very high	94.8	Very high	80 Å²	80	50.8 Å²	50.8	42%	0.419	27%	0.272	S	S	.	.	H	α-helix	trans	-72.8	-20.2	175.6	-67.5	-176.9	0	0	0	112.7	W142 L144 P145 T146 V151 W152	W142-L148 VanDerWaalsContact CZ2-C 3.45Å; W142-L148 HydrophobicContact CZ2-CB 3.91Å; L144-L148 HydrophobicContact CB-CD1 4.36Å; P145-L148 HydrophobicContact CB-CD1 4.45Å; P145-L148 HydrophobicContact CB-CG 4.35Å; P145-L148 HydrophobicContact CG-CD1 4.23Å; P145-L148 WeakPolarHBondContact O-CB 3.37Å; P145-L148 PolarHBondContact O-N 3.45Å; T146-L148 PolarHBondContact O-N 3Å; L148-V151 PolarHBondContact O-N 3.49Å; L148-W152 VanDerWaalsContact O-CB 3.31Å; L148-W152 WeakPolarHBondContact O-CB 3.31Å; L148-W152 PolarHBondContact O-N 3.45Å
149	C	96.1	Very high	95.2	Very high	0 Å²	0	44.9 Å²	44.9	0%	0	25%	0.249	C	C	.	.	H	α-helix	trans	-63.6	-51.9	176	171.8	0	0	0	0	111	W142 T146 K147 V151 W152 I153 V222 F223 C228	W142-C149 HydrophobicContact CD2-CB 4.15Å; W142-C149 VanDerWaalsContact CZ2-CA 3.43Å; W142-C149 HydrophobicContact CZ2-CB 3.94Å; W142-C149 VanDerWaalsContact CZ2-N 3.28Å; T146-C149 VanDerWaalsContact O-CB 3.3Å; T146-C149 WeakPolarHBondContact O-CB 3.4Å; T146-C149 PolarHBondContact O-N 3.36Å; T146-C149 VanDerWaalsContact O-N 3.08Å; K147-C149 VanDerWaalsContact C-N 3.27Å; K147-C149 PolarHBondContact O-N 2.67Å; C149-V151 VanDerWaalsContact C-N 3.27Å; C149-V151 PolarHBondContact O-N 3.01Å; C149-W152 PolarHBondContact O-N 2.96Å; C149-W152 VanDerWaalsContact O-N 3.13Å; C149-I153 WeakPolarHBondContact O-CG1 3.27Å; C149-I153 PolarHBondContact O-N 2.99Å; C149-V222 PolarHBondContact SG-O 3.43Å; C149-F223 HydrophobicContact CB-CE1 4.1Å; C149-F223 HydrophobicContact CB-CE2 3.83Å; C149-F223 HydrophobicContact CB-CZ 3.4Å; C149-F223 VanDerWaalsContact CB-CZ 3.4Å; C149-C228 WeakPolarHBondContact CA-SG 3.42Å; C149-C228 HydrophobicContact CB-CB 3.91Å; C149-C228 WeakPolarHBondContact CB-SG 3.34Å; C149-C228 VanDerWaalsContact SG-CA 3.5Å; C149-C228 WeakPolarHBondContact SG-CB 3.45Å; C149-C228 CovalentContact SG-SG 2.02Å; C149-C228 PolarHBondContact SG-SG 3.45Å
150	A	95.6	Very high	95.5	Very high	1 Å²	1	43.3 Å²	43.3	1%	0.008	23%	0.23	C	C	.	.	H	α-helix	trans	-59.9	-37.8	177.1	0	0	0	0	0	112.3	Y154 L216 V222	A150-Y154 VanDerWaalsContact O-CB 3.25Å; A150-Y154 WeakPolarHBondContact O-CB 3.36Å; A150-Y154 PolarHBondContact O-N 3.19Å; A150-L216 HydrophobicContact CB-CD2 3.9Å; A150-L216 HydrophobicContact CB-CG 4.17Å; A150-V222 HydrophobicContact CB-CG1 4.25Å
151	V	96.6	Very high	95.8	Very high	58 Å²	58	39.2 Å²	39.2	35%	0.352	21%	0.214	S	C	.	.	H	α-helix	trans	-66.9	-42.1	175.5	176.1	0	0	0	0	111.4	K147 L148 C149 Y154 L155	K147-V151 WeakPolarHBondContact O-CG2 3.35Å; L148-V151 PolarHBondContact O-N 3.49Å; C149-V151 VanDerWaalsContact C-N 3.27Å; C149-V151 PolarHBondContact O-N 3.01Å; V151-Y154 WeakPolarHBondContact O-CB 3.37Å; V151-Y154 PolarHBondContact O-N 3.48Å; V151-L155 HydrophobicContact CG1-CD1 4.18Å; V151-L155 HydrophobicContact CG1-CG 4.46Å; V151-L155 VanDerWaalsContact O-CG 3.31Å; V151-L155 WeakPolarHBondContact O-CG 3.38Å; V151-L155 PolarHBondContact O-N 3.42Å
152	W	97.8	Very high	96.1	Very high	31 Å²	31	36 Å²	36	12%	0.117	20%	0.195	C	C	.	.	H	α-helix	trans	-65.4	-46.7	178.3	172.3	72.5	0	0	0	111.8	V128 V131 W142 L148 C149 Y154 L155 D156 C228	V128-W152 PolarHBondContact O-NE1 2.87Å; V128-W152 VanDerWaalsContact O-NE1 3.16Å; V131-W152 HydrophobicContact CB-CG 4.36Å; V131-W152 HydrophobicContact CG1-CB 4.5Å; V131-W152 VanDerWaalsContact CG1-CD1 3.45Å; V131-W152 HydrophobicContact CG1-CD2 4.18Å; V131-W152 HydrophobicContact CG1-CG 3.79Å; W142-W152 HydrophobicContact CH2-CB 3.82Å; W142-W152 HydrophobicContact CH2-CD2 4.29Å; W142-W152 HydrophobicContact CH2-CE3 4.36Å; W142-W152 HydrophobicContact CH2-CG 4.08Å; W142-W152 HydrophobicContact CZ3-CB 4.49Å; W142-W152 HydrophobicContact CZ3-CD2 4.09Å; W142-W152 AromaticContact CZ3-CE3 3.95Å; W142-W152 HydrophobicContact CZ3-CE3 3.95Å; W142-W152 HydrophobicContact CZ3-CG 4.34Å; L148-W152 VanDerWaalsContact O-CB 3.31Å; L148-W152 WeakPolarHBondContact O-CB 3.31Å; L148-W152 PolarHBondContact O-N 3.45Å; C149-W152 PolarHBondContact O-N 2.96Å; C149-W152 VanDerWaalsContact O-N 3.13Å; W152-Y154 VanDerWaalsContact C-N 3.3Å; W152-Y154 PolarHBondContact O-N 3.19Å; W152-L155 PolarHBondContact O-N 2.83Å; W152-D156 PolarHBondContact O-N 3.43Å; W152-C228 VanDerWaalsContact CE3-SG 3.52Å; W152-C228 HydrophobicContact CZ3-CB 4.44Å
153	I	96.5	Very high	96.1	Very high	10 Å²	10	35 Å²	35	5%	0.051	19%	0.191	C	C	.	.	H	α-helix	trans	-60.4	-42.2	174.9	-60.9	171.8	0	0	0	110.3	C149 L155 D156 V157 I211 V222 L230	C149-I153 WeakPolarHBondContact O-CG1 3.27Å; C149-I153 PolarHBondContact O-N 2.99Å; I153-L155 PolarHBondContact O-N 3.43Å; I153-D156 PolarHBondContact O-N 2.9Å; I153-V157 HydrophobicContact CG2-CG2 4.34Å; I153-V157 WeakPolarHBondContact O-CG2 3.22Å; I153-V157 PolarHBondContact O-N 3.26Å; I153-I211 HydrophobicContact CB-CG2 4.11Å; I153-I211 HydrophobicContact CG2-CD1 4.45Å; I153-I211 HydrophobicContact CG2-CG2 3.77Å; I153-V222 HydrophobicContact CD1-CB 3.94Å; I153-V222 HydrophobicContact CD1-CG1 4.06Å; I153-L230 HydrophobicContact CG2-CB 4.41Å; I153-L230 HydrophobicContact CG2-CD1 4.46Å
154	Y	97.3	Very high	96.1	Very high	43 Å²	43	32.7 Å²	32.7	17%	0.169	18%	0.176	C	C	.	.	H	α-helix	trans	-57.2	-48.5	175.1	167.3	-107.2	0	0	0	112.3	A150 V151 W152 V157 L158 S208 P212	A150-Y154 VanDerWaalsContact O-CB 3.25Å; A150-Y154 WeakPolarHBondContact O-CB 3.36Å; A150-Y154 PolarHBondContact O-N 3.19Å; V151-Y154 WeakPolarHBondContact O-CB 3.37Å; V151-Y154 PolarHBondContact O-N 3.48Å; W152-Y154 VanDerWaalsContact C-N 3.3Å; W152-Y154 PolarHBondContact O-N 3.19Å; Y154-V157 PolarHBondContact O-N 3.34Å; Y154-L158 HydrophobicContact CE1-CD2 4.04Å; Y154-L158 WeakPolarHBondContact O-CB 3.44Å; Y154-L158 PolarHBondContact O-N 3.43Å; Y154-S208 WeakPolarHBondContact CD2-O 3.36Å; Y154-P212 HydrophobicContact CD2-CG 3.67Å; Y154-P212 HydrophobicContact CE2-CG 4.2Å; Y154-P212 HydrophobicContact CG-CG 3.96Å
155	L	98.1	Very high	96.1	Very high	39 Å²	39	31.3 Å²	31.3	20%	0.204	17%	0.169	C	C	.	.	H	α-helix	trans	-66	-40.1	-179.9	-70.2	176.3	0	0	0	112	L127 V128 V151 W152 I153 L158 F159	L127-L155 HydrophobicContact CB-CD1 4.48Å; L127-L155 HydrophobicContact CD1-CD1 4.5Å; V128-L155 HydrophobicContact CG2-CB 4Å; V151-L155 HydrophobicContact CG1-CD1 4.18Å; V151-L155 HydrophobicContact CG1-CG 4.46Å; V151-L155 VanDerWaalsContact O-CG 3.31Å; V151-L155 WeakPolarHBondContact O-CG 3.38Å; V151-L155 PolarHBondContact O-N 3.42Å; W152-L155 PolarHBondContact O-N 2.83Å; I153-L155 PolarHBondContact O-N 3.43Å; L155-L158 PolarHBondContact O-N 2.95Å; L155-F159 HydrophobicContact CB-CD2 4.34Å; L155-F159 HydrophobicContact CB-CE2 3.99Å; L155-F159 HydrophobicContact CD2-CE2 3.89Å; L155-F159 HydrophobicContact CD2-CZ 3.99Å; L155-F159 HydrophobicContact CG-CE2 4.42Å; L155-F159 WeakPolarHBondContact O-CD2 3.14Å; L155-F159 WeakPolarHBondContact O-CG 3.43Å; L155-F159 PolarHBondContact O-N 2.91Å
156	D	97.4	Very high	96.1	Very high	26 Å²	26	27.2 Å²	27.2	14%	0.139	14%	0.142	C	C	.	.	H	α-helix	trans	-58.9	-53.6	175	-171.5	5.9	0	0	0	111	V128 W152 I153 L158 F159 S160 Y370	V128-D156 HydrophobicContact CG1-CB 3.62Å; V128-D156 HydrophobicContact CG2-CB 4.27Å; W152-D156 PolarHBondContact O-N 3.43Å; I153-D156 PolarHBondContact O-N 2.9Å; D156-L158 VanDerWaalsContact C-N 3.31Å; D156-L158 PolarHBondContact O-N 3.18Å; D156-F159 PolarHBondContact O-N 3.44Å; D156-S160 WeakPolarHBondContact O-CB 3.45Å; D156-S160 PolarHBondContact O-N 2.97Å; D156-S160 PolarHBondContact O-OG 3.25Å; D156-S160 PolarHBondContact OD1-OG 3.44Å; D156-Y370 PolarHBondContact OD2-OH 2.81Å
157	V	96.1	Very high	96.1	Very high	37 Å²	37	23.9 Å²	23.9	22%	0.224	12%	0.122	C	C	.	.	H	α-helix	trans	-64.4	-38.5	179.5	-179.9	0	0	0	0	110.8	I153 Y154 T161 I211	I153-V157 HydrophobicContact CG2-CG2 4.34Å; I153-V157 WeakPolarHBondContact O-CG2 3.22Å; I153-V157 PolarHBondContact O-N 3.26Å; Y154-V157 PolarHBondContact O-N 3.34Å; V157-T161 WeakPolarHBondContact O-CB 3.35Å; V157-T161 PolarHBondContact O-N 3.39Å; V157-T161 PolarHBondContact O-OG1 3.49Å; V157-I211 HydrophobicContact CB-CD1 3.68Å; V157-I211 HydrophobicContact CG1-CD1 3.81Å; V157-I211 HydrophobicContact CG2-CD1 3.62Å
158	L	97.8	Very high	96.1	Very high	12 Å²	12	19.9 Å²	19.9	6%	0.063	11%	0.105	C	C	.	.	H	α-helix	trans	-61.2	-54.6	178.7	172.3	61.3	0	0	0	112	Y154 L155 D156 T161 A162 V205 S208	Y154-L158 HydrophobicContact CE1-CD2 4.04Å; Y154-L158 WeakPolarHBondContact O-CB 3.44Å; Y154-L158 PolarHBondContact O-N 3.43Å; L155-L158 PolarHBondContact O-N 2.95Å; D156-L158 VanDerWaalsContact C-N 3.31Å; D156-L158 PolarHBondContact O-N 3.18Å; L158-T161 PolarHBondContact O-N 3.49Å; L158-A162 VanDerWaalsContact O-CB 3.3Å; L158-A162 WeakPolarHBondContact O-CB 3.46Å; L158-A162 PolarHBondContact O-N 3.19Å; L158-V205 HydrophobicContact CD1-CB 4.35Å; L158-V205 HydrophobicContact CD1-CG2 3.66Å; L158-V205 HydrophobicContact CD2-CG2 4.46Å; L158-S208 VanDerWaalsContact CA-OG 3.25Å; L158-S208 WeakPolarHBondContact CA-OG 3.47Å; L158-S208 PolarHBondContact N-OG 3.02Å
159	F	98.3	Very high	96	Very high	11 Å²	11	17 Å²	17	5%	0.048	9%	0.093	C	C	.	.	H	α-helix	trans	-70.8	-37.9	-175.7	-61.7	-47.4	0	0	0	111.6	L123 L124 L127 V128 L155 D156 A162 S163 W201	L123-F159 HydrophobicContact CB-CD1 3.96Å; L123-F159 HydrophobicContact CB-CD2 4.11Å; L123-F159 HydrophobicContact CB-CE1 3.69Å; L123-F159 HydrophobicContact CB-CE2 3.83Å; L123-F159 HydrophobicContact CB-CG 4.19Å; L123-F159 HydrophobicContact CB-CZ 3.62Å; L123-F159 HydrophobicContact CD1-CD1 4.26Å; L123-F159 HydrophobicContact CD1-CE1 3.53Å; L123-F159 HydrophobicContact CD1-CZ 3.92Å; L123-F159 HydrophobicContact CG-CE1 4.23Å; L123-F159 HydrophobicContact CG-CZ 4.28Å; L124-F159 HydrophobicContact CB-CB 4.03Å; L124-F159 HydrophobicContact CD1-CB 4.08Å; L127-F159 HydrophobicContact CB-CE2 4.45Å; L127-F159 HydrophobicContact CD1-CE2 3.84Å; L127-F159 HydrophobicContact CD1-CZ 4Å; V128-F159 HydrophobicContact CG2-CD2 4.11Å; L155-F159 HydrophobicContact CB-CD2 4.34Å; L155-F159 HydrophobicContact CB-CE2 3.99Å; L155-F159 HydrophobicContact CD2-CE2 3.89Å; L155-F159 HydrophobicContact CD2-CZ 3.99Å; L155-F159 HydrophobicContact CG-CE2 4.42Å; L155-F159 WeakPolarHBondContact O-CD2 3.14Å; L155-F159 WeakPolarHBondContact O-CG 3.43Å; L155-F159 PolarHBondContact O-N 2.91Å; D156-F159 PolarHBondContact O-N 3.44Å; F159-A162 PolarHBondContact O-N 3.48Å; F159-S163 PolarHBondContact O-N 3.22Å; F159-S163 PolarHBondContact O-OG 3.32Å; F159-W201 AromaticContact CD1-CH2 3.98Å; F159-W201 HydrophobicContact CD1-CH2 3.98Å; F159-W201 AromaticContact CD1-CZ3 3.99Å; F159-W201 HydrophobicContact CD1-CZ3 3.99Å; F159-W201 HydrophobicContact CE1-CH2 4.12Å; F159-W201 HydrophobicContact CE1-CZ3 4.04Å
160	S	95.7	Very high	95.7	Very high	20 Å²	20	17.1 Å²	17.1	14%	0.14	9%	0.093	C	C	.	.	H	α-helix	trans	-63.5	-43.5	173.9	-63.1	0	0	0	0	112	D156 S163 I164	D156-S160 WeakPolarHBondContact O-CB 3.45Å; D156-S160 PolarHBondContact O-N 2.97Å; D156-S160 PolarHBondContact O-OG 3.25Å; D156-S160 PolarHBondContact OD1-OG 3.44Å; S160-S163 PolarHBondContact O-N 2.95Å; S160-I164 PolarHBondContact O-N 2.99Å
161	T	95.9	Very high	95.4	Very high	4 Å²	4	17.1 Å²	17.1	3%	0.025	9%	0.093	C	C	.	.	H	α-helix	trans	-65.4	-40.1	174.6	-56.6	0	0	0	0	111.1	V157 L158 S163 I164 M165 I207 A243	V157-T161 WeakPolarHBondContact O-CB 3.35Å; V157-T161 PolarHBondContact O-N 3.39Å; V157-T161 PolarHBondContact O-OG1 3.49Å; L158-T161 PolarHBondContact O-N 3.49Å; T161-S163 VanDerWaalsContact C-N 3.35Å; T161-S163 PolarHBondContact O-N 3.21Å; T161-I164 VanDerWaalsContact O-CG2 3.32Å; T161-I164 WeakPolarHBondContact O-CG2 3.33Å; T161-M165 HydrophobicContact CG2-CG 4.08Å; T161-M165 VanDerWaalsContact O-CB 3.24Å; T161-M165 WeakPolarHBondContact O-CB 3.48Å; T161-M165 WeakPolarHBondContact O-CG 3.45Å; T161-M165 PolarHBondContact O-N 3.24Å; T161-I207 HydrophobicContact CG2-CB 4.29Å; T161-I207 HydrophobicContact CG2-CD1 3.92Å; T161-I207 HydrophobicContact CG2-CG2 4.18Å; T161-A243 HydrophobicContact CG2-CB 4.29Å
162	A	97.4	Very high	95	Very high	0 Å²	0	17.4 Å²	17.4	0%	0	9%	0.093	C	C	.	.	H	α-helix	trans	-60.5	-44.9	174.7	0	0	0	0	0	110.9	A120 L158 F159 M165 H166 W201 S204	A120-A162 HydrophobicContact CB-CB 4.12Å; L158-A162 VanDerWaalsContact O-CB 3.3Å; L158-A162 WeakPolarHBondContact O-CB 3.46Å; L158-A162 PolarHBondContact O-N 3.19Å; F159-A162 PolarHBondContact O-N 3.48Å; A162-M165 PolarHBondContact O-N 2.98Å; A162-H166 PolarHBondContact O-N 3.41Å; A162-H166 PolarHBondContact O-ND1 3.02Å; A162-W201 HydrophobicContact CB-CE3 4.25Å; A162-W201 HydrophobicContact CB-CH2 4.19Å; A162-W201 HydrophobicContact CB-CZ3 4Å; A162-S204 VanDerWaalsContact CA-OG 3.25Å; A162-S204 WeakPolarHBondContact CA-OG 3.47Å; A162-S204 PolarHBondContact N-OG 3.41Å
163	S	95.4	Very high	94.4	Very high	4 Å²	4	16.3 Å²	16.3	3%	0.028	9%	0.089	C	C	.	.	H	α-helix	trans	-60.9	-49.6	-179.3	-69.4	0	0	0	0	112.5	D121 F159 S160 T161 M165 H166 L167	D121-S163 PolarHBondContact OD1-OG 3.28Å; F159-S163 PolarHBondContact O-N 3.22Å; F159-S163 PolarHBondContact O-OG 3.32Å; S160-S163 PolarHBondContact O-N 2.95Å; T161-S163 VanDerWaalsContact C-N 3.35Å; T161-S163 PolarHBondContact O-N 3.21Å; S163-M165 PolarHBondContact O-N 3.28Å; S163-H166 PolarHBondContact O-N 2.84Å; S163-L167 WeakPolarHBondContact O-CG 3.47Å; S163-L167 PolarHBondContact O-N 2.73Å; S163-L167 VanDerWaalsContact O-N 3.12Å
164	I	94.7	Very high	93.8	Very high	3 Å²	3	18.4 Å²	18.4	2%	0.015	10%	0.096	C	C	.	.	H	α-helix	trans	-66.5	-37.6	177.4	-168.5	176.5	0	0	0	112.7	S160 T161 H166 L167 C168 A243 F244 P247 F332	S160-I164 PolarHBondContact O-N 2.99Å; T161-I164 VanDerWaalsContact O-CG2 3.32Å; T161-I164 WeakPolarHBondContact O-CG2 3.33Å; I164-H166 VanDerWaalsContact C-N 3.33Å; I164-H166 PolarHBondContact O-N 2.93Å; I164-L167 PolarHBondContact O-N 2.85Å; I164-C168 WeakPolarHBondContact O-CB 3.41Å; I164-C168 PolarHBondContact O-N 3.05Å; I164-A243 VanDerWaalsContact CG2-O 3.3Å; I164-A243 WeakPolarHBondContact CG2-O 3.38Å; I164-F244 HydrophobicContact CD1-CD2 3.79Å; I164-F244 HydrophobicContact CD1-CE2 4.32Å; I164-P247 HydrophobicContact CD1-CB 3.85Å; I164-P247 HydrophobicContact CG1-CB 3.96Å; I164-P247 HydrophobicContact CG2-CB 4.49Å; I164-F332 HydrophobicContact CB-CE1 3.93Å; I164-F332 HydrophobicContact CB-CZ 3.68Å; I164-F332 HydrophobicContact CD1-CE1 3.7Å; I164-F332 HydrophobicContact CD1-CZ 4.23Å; I164-F332 HydrophobicContact CG1-CE1 3.71Å; I164-F332 HydrophobicContact CG1-CZ 4.03Å
165	M	95.3	Very high	93.3	Very high	31 Å²	31	18.5 Å²	18.5	15%	0.153	10%	0.097	C	C	.	.	H	α-helix	trans	-67	-34.1	177.6	-71.1	-63.1	-65.3	0	0	112.1	T161 A162 S163 A169 V200 I203 P247	T161-M165 HydrophobicContact CG2-CG 4.08Å; T161-M165 VanDerWaalsContact O-CB 3.24Å; T161-M165 WeakPolarHBondContact O-CB 3.48Å; T161-M165 WeakPolarHBondContact O-CG 3.45Å; T161-M165 PolarHBondContact O-N 3.24Å; A162-M165 PolarHBondContact O-N 2.98Å; S163-M165 PolarHBondContact O-N 3.28Å; M165-A169 VanDerWaalsContact O-CB 3.31Å; M165-A169 WeakPolarHBondContact O-CB 3.43Å; M165-A169 PolarHBondContact O-N 3.43Å; M165-V200 HydrophobicContact CB-CG1 3.72Å; M165-I203 HydrophobicContact CE-CD1 4.46Å; M165-I203 HydrophobicContact CE-CG2 3.83Å; M165-P247 HydrophobicContact SD-CB 4Å; M165-P247 HydrophobicContact SD-CG 3.65Å
166	H	95.5	Very high	92.7	Very high	0 Å²	0	20.4 Å²	20.4	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-65.2	-44	170.7	-78.4	88.2	0	0	0	111.7	S116 L117 A162 S163 I164 C168 A169 I170 V200 W201	S116-H166 VanDerWaalsContact CB-NE2 3.33Å; S116-H166 WeakPolarHBondContact CB-NE2 3.48Å; S116-H166 PolarHBondContact OG-CE1 2.73Å; S116-H166 PolarHBondContact OG-NE2 3.45Å; L117-H166 HydrophobicContact CB-CB 4.16Å; L117-H166 HydrophobicContact CD1-CB 4.21Å; A162-H166 PolarHBondContact O-N 3.41Å; A162-H166 PolarHBondContact O-ND1 3.02Å; S163-H166 PolarHBondContact O-N 2.84Å; I164-H166 VanDerWaalsContact C-N 3.33Å; I164-H166 PolarHBondContact O-N 2.93Å; H166-C168 VanDerWaalsContact C-N 3.34Å; H166-C168 PolarHBondContact O-N 3.27Å; H166-A169 PolarHBondContact O-N 3.09Å; H166-I170 WeakPolarHBondContact O-CD1 3.31Å; H166-I170 WeakPolarHBondContact O-CG1 3.31Å; H166-I170 PolarHBondContact O-N 3.35Å; H166-V200 VanDerWaalsContact CE1-CG1 3.45Å; H166-V200 WeakPolarHBondContact CE1-CG1 3.22Å; H166-V200 WeakPolarHBondContact ND1-CG1 3.44Å; H166-W201 AromaticContact CE1-CE2 3.98Å; H166-W201 AromaticContact CE1-NE1 3.59Å; H166-W201 AromaticContact NE2-NE1 3.8Å
167	L	92	Very high	91.9	Very high	2 Å²	2	19.7 Å²	19.7	1%	0.01	10%	0.104	C	C	.	.	H	α-helix	trans	-60.7	-43.7	175.8	-66.5	176.2	0	0	0	111.7	L117 S163 I164 I170 S171 M251 V328 F329 F332	L117-L167 HydrophobicContact CD2-CD2 3.74Å; L117-L167 HydrophobicContact CD2-CG 4.39Å; S163-L167 WeakPolarHBondContact O-CG 3.47Å; S163-L167 PolarHBondContact O-N 2.73Å; S163-L167 VanDerWaalsContact O-N 3.12Å; I164-L167 PolarHBondContact O-N 2.85Å; L167-I170 PolarHBondContact O-N 2.94Å; L167-S171 PolarHBondContact O-N 3.02Å; L167-M251 HydrophobicContact CB-SD 4.04Å; L167-V328 HydrophobicContact CD2-CG1 3.8Å; L167-F329 HydrophobicContact CB-CD1 4.15Å; L167-F329 HydrophobicContact CB-CE1 3.99Å; L167-F329 HydrophobicContact CD2-CD1 4.02Å; L167-F329 HydrophobicContact CD2-CE1 3.86Å; L167-F329 HydrophobicContact CG-CD1 4.49Å; L167-F329 HydrophobicContact CG-CE1 4.49Å; L167-F332 HydrophobicContact CD1-CB 3.94Å; L167-F332 HydrophobicContact CD1-CD1 4.21Å; L167-F332 HydrophobicContact CD1-CD2 3.65Å; L167-F332 HydrophobicContact CD1-CE2 4.23Å; L167-F332 HydrophobicContact CD1-CG 3.65Å
168	C	93.1	Very high	91.1	Very high	6 Å²	6	18.4 Å²	18.4	4%	0.041	10%	0.096	C	C	.	.	H	α-helix	trans	-60.7	-47.1	175.1	-176.6	0	0	0	0	111.7	I164 H166 I170 S171 L172 I250	I164-C168 WeakPolarHBondContact O-CB 3.41Å; I164-C168 PolarHBondContact O-N 3.05Å; H166-C168 VanDerWaalsContact C-N 3.34Å; H166-C168 PolarHBondContact O-N 3.27Å; C168-I170 VanDerWaalsContact C-N 3.34Å; C168-I170 PolarHBondContact O-N 3.45Å; C168-S171 PolarHBondContact O-N 3.25Å; C168-L172 PolarHBondContact O-N 3.08Å; C168-I250 WeakPolarHBondContact SG-CG2 3.42Å
169	A	92.5	Very high	90.3	Very high	20 Å²	20	25.3 Å²	25.3	17%	0.165	12%	0.121	C	C	.	.	H	α-helix	trans	-62.1	-39.9	176.9	0	0	0	0	0	112.3	F113 M165 H166 D173 V200	F113-A169 HydrophobicContact CD1-CB 4.31Å; F113-A169 HydrophobicContact CE1-CB 3.89Å; M165-A169 VanDerWaalsContact O-CB 3.31Å; M165-A169 WeakPolarHBondContact O-CB 3.43Å; M165-A169 PolarHBondContact O-N 3.43Å; H166-A169 PolarHBondContact O-N 3.09Å; A169-D173 WeakPolarHBondContact O-CB 3.47Å; A169-D173 PolarHBondContact O-N 3.48Å; A169-V200 HydrophobicContact CB-CG2 3.93Å
170	I	90.5	Very high	89.4	Confident	1 Å²	1	28.4 Å²	28.4	1%	0.005	14%	0.138	C	C	.	.	H	α-helix	trans	-62.6	-46.8	174.5	-68.6	160.4	0	0	0	110.3	T110 F113 L114 H166 L167 C168 L172 D173 R174 L325 F329	T110-I170 HydrophobicContact CG2-CG2 4.28Å; F113-I170 HydrophobicContact CB-CD1 3.87Å; F113-I170 HydrophobicContact CB-CG1 3.56Å; F113-I170 HydrophobicContact CD1-CG1 4.49Å; F113-I170 HydrophobicContact CG-CG1 4.1Å; L114-I170 HydrophobicContact CD2-CD1 3.68Å; H166-I170 WeakPolarHBondContact O-CD1 3.31Å; H166-I170 WeakPolarHBondContact O-CG1 3.31Å; H166-I170 PolarHBondContact O-N 3.35Å; L167-I170 PolarHBondContact O-N 2.94Å; C168-I170 VanDerWaalsContact C-N 3.34Å; C168-I170 PolarHBondContact O-N 3.45Å; I170-L172 PolarHBondContact O-N 3.44Å; I170-D173 PolarHBondContact O-N 2.88Å; I170-R174 HydrophobicContact CG2-CG 4.39Å; I170-R174 VanDerWaalsContact O-CG 3.29Å; I170-R174 WeakPolarHBondContact O-CG 3.32Å; I170-R174 PolarHBondContact O-N 2.96Å; I170-L325 HydrophobicContact CG2-CD1 4.02Å; I170-L325 HydrophobicContact CG2-CD2 3.84Å; I170-F329 HydrophobicContact CG2-CZ 4.35Å
171	S	88.7	Confident	88.3	Confident	2 Å²	2	31.3 Å²	31.3	1%	0.014	16%	0.156	C	C	.	.	H	α-helix	trans	-59.6	-46.7	178.8	-169.7	0	0	0	0	111.9	L167 C168 R174 Y175 T254	L167-S171 PolarHBondContact O-N 3.02Å; C168-S171 PolarHBondContact O-N 3.25Å; S171-R174 PolarHBondContact O-N 3.45Å; S171-Y175 WeakPolarHBondContact O-CB 3.49Å; S171-Y175 PolarHBondContact O-N 3.19Å; S171-T254 WeakPolarHBondContact CB-OG1 3.27Å; S171-T254 PolarHBondContact OG-OG1 3.28Å
172	L	88.8	Confident	86.9	Confident	64 Å²	64	38.2 Å²	38.2	34%	0.335	19%	0.192	S	C	.	.	H	α-helix	trans	-62.5	-45.2	175.9	-80.4	166.7	0	0	0	112.5	C168 I170 R174 Y175 I176 I250 T254	C168-L172 PolarHBondContact O-N 3.08Å; I170-L172 PolarHBondContact O-N 3.44Å; L172-R174 VanDerWaalsContact C-N 3.32Å; L172-R174 PolarHBondContact O-N 3.27Å; L172-Y175 PolarHBondContact O-N 2.89Å; L172-I176 VanDerWaalsContact O-CG1 3.27Å; L172-I176 WeakPolarHBondContact O-CG1 3.29Å; L172-I176 PolarHBondContact O-N 3.49Å; L172-I250 HydrophobicContact CD1-CG2 3.99Å; L172-I250 HydrophobicContact CD2-CG2 4.33Å; L172-I250 HydrophobicContact CG-CG2 4.19Å; L172-T254 HydrophobicContact CD2-CG2 3.41Å; L172-T254 VanDerWaalsContact CD2-CG2 3.41Å; L172-T254 HydrophobicContact CG-CG2 3.96Å
173	D	86.4	Confident	85.4	Confident	7 Å²	7	42.7 Å²	42.7	4%	0.037	21%	0.212	C	C	.	.	H	α-helix	trans	-60.2	-43.5	178.1	-175.8	85	0	0	0	111.2	A169 I170 I176 A177 H184 K196	A169-D173 WeakPolarHBondContact O-CB 3.47Å; A169-D173 PolarHBondContact O-N 3.48Å; I170-D173 PolarHBondContact O-N 2.88Å; D173-I176 PolarHBondContact O-N 3.27Å; D173-A177 VanDerWaalsContact O-CB 3.3Å; D173-A177 WeakPolarHBondContact O-CB 3.43Å; D173-A177 PolarHBondContact O-N 3.43Å; D173-H184 IonicContact OD1-NE2 2.79Å; D173-H184 IonicContact OD2-NE2 3.92Å; D173-K196 IonicContact OD1-NZ 3.76Å; D173-K196 PolarHBondContact OD1-NZ 3.32Å
174	R	83.5	Confident	83.9	Confident	54 Å²	54	44 Å²	44	20%	0.204	22%	0.218	C	C	.	.	H	α-helix	trans	-63.7	-45.8	175.3	-69	-57.1	82.4	-163.6	-2.3	112.6	T110 I170 S171 L172 I176 A177 I178 L325	T110-R174 PolarHBondContact OG1-NE 3.43Å; T110-R174 PolarHBondContact OG1-NH2 3.33Å; I170-R174 HydrophobicContact CG2-CG 4.39Å; I170-R174 VanDerWaalsContact O-CG 3.29Å; I170-R174 WeakPolarHBondContact O-CG 3.32Å; I170-R174 PolarHBondContact O-N 2.96Å; S171-R174 PolarHBondContact O-N 3.45Å; L172-R174 VanDerWaalsContact C-N 3.32Å; L172-R174 PolarHBondContact O-N 3.27Å; R174-I176 VanDerWaalsContact C-N 3.33Å; R174-I176 PolarHBondContact O-N 3.07Å; R174-A177 WeakPolarHBondContact O-CB 3.38Å; R174-A177 PolarHBondContact O-N 3.47Å; R174-I178 WeakPolarHBondContact O-CD1 3.4Å; R174-I178 WeakPolarHBondContact O-CG1 3.43Å; R174-I178 PolarHBondContact O-N 2.88Å; R174-L325 HydrophobicContact CG-CD1 3.56Å
175	Y	85.9	Confident	82.5	Confident	46 Å²	46	48.3 Å²	48.3	18%	0.18	25%	0.249	C	C	.	.	H	α-helix	trans	-57.8	-46.8	177.2	173.9	-113.4	0	0	0	111.8	S171 L172 A177 I178 R179 L257 T258	S171-Y175 WeakPolarHBondContact O-CB 3.49Å; S171-Y175 PolarHBondContact O-N 3.19Å; L172-Y175 PolarHBondContact O-N 2.89Å; Y175-A177 VanDerWaalsContact C-N 3.34Å; Y175-A177 PolarHBondContact O-N 3.3Å; Y175-I178 PolarHBondContact O-N 2.9Å; Y175-R179 WeakPolarHBondContact O-CB 3.34Å; Y175-R179 PolarHBondContact O-N 3.22Å; Y175-L257 HydrophobicContact CD2-CB 3.85Å; Y175-L257 HydrophobicContact CE2-CB 3.55Å; Y175-L257 HydrophobicContact CE2-CD1 4.43Å; Y175-T258 WeakPolarHBondContact CB-OG1 3.3Å
176	I	85.4	Confident	80.8	Confident	78 Å²	78	55.9 Å²	55.9	40%	0.4	28%	0.275	S	S	.	.	H	α-helix	trans	-65.5	-39.1	178.8	-66.3	166	0	0	0	111	L172 D173 R174 I178 R179 N180	L172-I176 VanDerWaalsContact O-CG1 3.27Å; L172-I176 WeakPolarHBondContact O-CG1 3.29Å; L172-I176 PolarHBondContact O-N 3.49Å; D173-I176 PolarHBondContact O-N 3.27Å; R174-I176 VanDerWaalsContact C-N 3.33Å; R174-I176 PolarHBondContact O-N 3.07Å; I176-I178 VanDerWaalsContact C-N 3.34Å; I176-I178 PolarHBondContact O-N 2.93Å; I176-R179 PolarHBondContact O-N 3.37Å; I176-N180 PolarHBondContact O-N 2.98Å
177	A	80.9	Confident	79.1	Confident	12 Å²	12	59.6 Å²	59.6	10%	0.099	29%	0.292	C	S	.	.	H	α-helix	trans	-59.9	-43.8	178.2	0	0	0	0	0	112.6	D173 R174 Y175 P181 H184	D173-A177 VanDerWaalsContact O-CB 3.3Å; D173-A177 WeakPolarHBondContact O-CB 3.43Å; D173-A177 PolarHBondContact O-N 3.43Å; R174-A177 WeakPolarHBondContact O-CB 3.38Å; R174-A177 PolarHBondContact O-N 3.47Å; Y175-A177 VanDerWaalsContact C-N 3.34Å; Y175-A177 PolarHBondContact O-N 3.3Å; A177-P181 WeakPolarHBondContact O-CA 3.33Å; A177-H184 VanDerWaalsContact CA-CD2 3.48Å; A177-H184 WeakPolarHBondContact CA-CD2 3.3Å; A177-H184 HydrophobicContact CB-CB 4.33Å; A177-H184 WeakPolarHBondContact CB-CD2 3.23Å
178	I	79.1	Confident	77.8	Confident	9 Å²	9	63.4 Å²	63.4	5%	0.046	31%	0.312	C	S	.	.	H	α-helix	trans	-72.8	-44.8	-179.5	-67.3	158.4	0	0	0	110.3	R174 Y175 I176 N180 T258 L262	R174-I178 WeakPolarHBondContact O-CD1 3.4Å; R174-I178 WeakPolarHBondContact O-CG1 3.43Å; R174-I178 PolarHBondContact O-N 2.88Å; Y175-I178 PolarHBondContact O-N 2.9Å; I176-I178 VanDerWaalsContact C-N 3.34Å; I176-I178 PolarHBondContact O-N 2.93Å; I178-N180 PolarHBondContact O-N 3.16Å; I178-T258 HydrophobicContact CD1-CG2 3.56Å; I178-L262 HydrophobicContact CD1-CD1 4.02Å; I178-L262 HydrophobicContact CD1-CD2 3.78Å; I178-L262 HydrophobicContact CD1-CG 3.88Å; I178-L262 HydrophobicContact CG1-CD2 4.13Å; I178-L262 HydrophobicContact CG2-CD2 4.08Å; I178-L262 HydrophobicContact CG2-CG 4.34Å
179	R	81.7	Confident	77.1	Confident	158 Å²	158	65.8 Å²	65.8	60%	0.596	33%	0.329	S	S	*	.	H	α-helix	trans	-66	-38.7	-178.5	-169.3	-172.4	-178	-166.8	1.3	112.8	Y175 I176	Y175-R179 WeakPolarHBondContact O-CB 3.34Å; Y175-R179 PolarHBondContact O-N 3.22Å; I176-R179 PolarHBondContact O-N 3.37Å
180	N	78.7	Confident	76.5	Confident	76 Å²	76	72 Å²	72	41%	0.406	35%	0.348	S	S	.	.			trans	-131	69.5	-170.9	-67.7	-29.6	0	0	0	111.8	I176 I178 I182 H183 H184	I176-N180 PolarHBondContact O-N 2.98Å; I178-N180 PolarHBondContact O-N 3.16Å; N180-I182 PolarHBondContact O-N 3.39Å; N180-H183 HydrophobicContact CB-CB 4.22Å; N180-H183 PolarHBondContact O-N 3Å; N180-H184 WeakPolarHBondContact O-CB 3.24Å; N180-H184 PolarHBondContact O-N 3.37Å
181	P	72.7	Confident	76.3	Confident	80 Å²	80	77.1 Å²	77.1	52%	0.519	38%	0.38	S	S	.	.	H	α-helix	trans	-64	-37.8	-171.1	23.4	-33.8	0	0	0	113.7	A177 H184 S185	A177-P181 WeakPolarHBondContact O-CA 3.33Å; P181-H184 PolarHBondContact O-N 2.92Å; P181-S185 WeakPolarHBondContact O-CB 3.48Å; P181-S185 PolarHBondContact O-N 3.22Å
182	I	66.9	Low	76.2	Confident	150 Å²	150	81.1 Å²	81.1	77%	0.769	40%	0.397	S	S	*	.	H	α-helix	trans	-67.1	-44.1	-179.7	-59.4	173.2	0	0	0	110.8	N180 R186	N180-I182 PolarHBondContact O-N 3.39Å; I182-R186 PolarHBondContact O-N 2.94Å
183	H	65.4	Low	76.1	Confident	94 Å²	94	78.3 Å²	78.3	44%	0.435	38%	0.383	S	S	.	.	H	α-helix	trans	-69.9	-42	176.6	-164.6	-88.6	0	0	0	110.3	N180 S185 R186 F187	N180-H183 HydrophobicContact CB-CB 4.22Å; N180-H183 PolarHBondContact O-N 3Å; H183-S185 VanDerWaalsContact C-N 3.34Å; H183-S185 PolarHBondContact O-N 3.46Å; H183-R186 PolarHBondContact O-N 3.45Å; H183-F187 AromaticContact CD2-CE2 3.65Å; H183-F187 AromaticContact CE1-CD2 3.41Å; H183-F187 VanDerWaalsContact CE1-CD2 3.41Å; H183-F187 WeakPolarHBondContact CE1-CD2 3.42Å; H183-F187 AromaticContact CE1-CE1 3.8Å; H183-F187 AromaticContact CE1-CE2 2.99Å; H183-F187 WeakPolarHBondContact CE1-CE2 3.32Å; H183-F187 AromaticContact CE1-CG 3.93Å; H183-F187 AromaticContact CE1-CZ 3.21Å; H183-F187 WeakPolarHBondContact CE1-CZ 3.46Å; H183-F187 AromaticContact CG-CD2 3.98Å; H183-F187 AromaticContact CG-CE2 3.89Å; H183-F187 AromaticContact ND1-CD2 3.46Å; H183-F187 WeakPolarHBondContact ND1-CD2 3.48Å; H183-F187 AromaticContact ND1-CE2 3.51Å; H183-F187 AromaticContact ND1-CG 4Å; H183-F187 AromaticContact NE2-CD2 3.85Å; H183-F187 AromaticContact NE2-CE2 3.05Å; H183-F187 WeakPolarHBondContact NE2-CE2 3.16Å; H183-F187 AromaticContact NE2-CZ 3.34Å; H183-F187 VanDerWaalsContact NE2-CZ 3.34Å; H183-F187 WeakPolarHBondContact NE2-CZ 3.35Å; H183-F187 WeakPolarHBondContact O-CB 3.48Å; H183-F187 WeakPolarHBondContact O-CD2 3.41Å; H183-F187 PolarHBondContact O-N 2.93Å; H183-F187 VanDerWaalsContact O-N 3.14Å
184	H	65.1	Low	76.4	Confident	30 Å²	30	81.5 Å²	81.5	14%	0.139	40%	0.397	C	S	.	.	H	α-helix	trans	-61.6	-39.8	178.1	-172.6	-87.6	0	0	0	112.6	D173 A177 N180 P181 R186 F187 N188	D173-H184 IonicContact OD1-NE2 2.79Å; D173-H184 IonicContact OD2-NE2 3.92Å; A177-H184 VanDerWaalsContact CA-CD2 3.48Å; A177-H184 WeakPolarHBondContact CA-CD2 3.3Å; A177-H184 HydrophobicContact CB-CB 4.33Å; A177-H184 WeakPolarHBondContact CB-CD2 3.23Å; N180-H184 WeakPolarHBondContact O-CB 3.24Å; N180-H184 PolarHBondContact O-N 3.37Å; P181-H184 PolarHBondContact O-N 2.92Å; H184-R186 PolarHBondContact O-N 3.39Å; H184-F187 CarbonylContact O-C 3.51Å; H184-F187 PolarHBondContact O-N 3.32Å; H184-F187 VanDerWaalsContact O-N 3.07Å; H184-N188 WeakPolarHBondContact O-CB 3.42Å; H184-N188 PolarHBondContact O-N 2.96Å
185	S	64.5	Low	76.8	Confident	95 Å²	95	81.7 Å²	81.7	66%	0.664	41%	0.41	S	S	*	.	H	α-helix	trans	-58.5	-44.3	175.2	-177	0	0	0	0	112.6	P181 H183 F187	P181-S185 WeakPolarHBondContact O-CB 3.48Å; P181-S185 PolarHBondContact O-N 3.22Å; H183-S185 VanDerWaalsContact C-N 3.34Å; H183-S185 PolarHBondContact O-N 3.46Å; S185-F187 PolarHBondContact O-N 2.87Å
186	R	59.5	Low	77.1	Confident	189 Å²	189	84 Å²	84	71%	0.713	42%	0.421	S	S	*	.	H	α-helix	trans	-70.4	-17.5	176.6	-163.2	172.5	78	154.7	1.9	113.4	I182 H183 H184	I182-R186 PolarHBondContact O-N 2.94Å; H183-R186 PolarHBondContact O-N 3.45Å; H184-R186 PolarHBondContact O-N 3.39Å
187	F	59.3	Low	77.6	Confident	79 Å²	79	81 Å²	81	35%	0.346	41%	0.405	S	S	.	.	H	α-helix	trans	-106.8	0.6	-176.5	-78.7	-106	0	0	0	114.2	H183 H184 S185 S189 K192	H183-F187 AromaticContact CD2-CE2 3.65Å; H183-F187 AromaticContact CE1-CD2 3.41Å; H183-F187 VanDerWaalsContact CE1-CD2 3.41Å; H183-F187 WeakPolarHBondContact CE1-CD2 3.42Å; H183-F187 AromaticContact CE1-CE1 3.8Å; H183-F187 AromaticContact CE1-CE2 2.99Å; H183-F187 WeakPolarHBondContact CE1-CE2 3.32Å; H183-F187 AromaticContact CE1-CG 3.93Å; H183-F187 AromaticContact CE1-CZ 3.21Å; H183-F187 WeakPolarHBondContact CE1-CZ 3.46Å; H183-F187 AromaticContact CG-CD2 3.98Å; H183-F187 AromaticContact CG-CE2 3.89Å; H183-F187 AromaticContact ND1-CD2 3.46Å; H183-F187 WeakPolarHBondContact ND1-CD2 3.48Å; H183-F187 AromaticContact ND1-CE2 3.51Å; H183-F187 AromaticContact ND1-CG 4Å; H183-F187 AromaticContact NE2-CD2 3.85Å; H183-F187 AromaticContact NE2-CE2 3.05Å; H183-F187 WeakPolarHBondContact NE2-CE2 3.16Å; H183-F187 AromaticContact NE2-CZ 3.34Å; H183-F187 VanDerWaalsContact NE2-CZ 3.34Å; H183-F187 WeakPolarHBondContact NE2-CZ 3.35Å; H183-F187 WeakPolarHBondContact O-CB 3.48Å; H183-F187 WeakPolarHBondContact O-CD2 3.41Å; H183-F187 PolarHBondContact O-N 2.93Å; H183-F187 VanDerWaalsContact O-N 3.14Å; H184-F187 CarbonylContact O-C 3.51Å; H184-F187 PolarHBondContact O-N 3.32Å; H184-F187 VanDerWaalsContact O-N 3.07Å; S185-F187 PolarHBondContact O-N 2.87Å; F187-S189 PolarHBondContact O-N 3.31Å; F187-K192 HydrophobicContact CD1-CD 4.12Å; F187-K192 WeakPolarHBondContact O-CD 3.38Å
188	N	65.1	Low	78.4	Confident	81 Å²	81	85.5 Å²	85.5	43%	0.433	43%	0.426	S	S	.	.			trans	-79.1	34	-178.3	-163.2	23.4	0	0	0	114.1	A109 H184	A109-N188 VanDerWaalsContact CB-OD1 3.29Å; A109-N188 WeakPolarHBondContact CB-OD1 3.35Å; H184-N188 WeakPolarHBondContact O-CB 3.42Å; H184-N188 PolarHBondContact O-N 2.96Å
189	S	77.9	Confident	79.2	Confident	57 Å²	57	87.3 Å²	87.3	40%	0.399	44%	0.443	S	S	.	.			trans	-79	139.6	177.7	175	0	0	0	0	110.9	F187 T191 K192 A193	F187-S189 PolarHBondContact O-N 3.31Å; S189-T191 VanDerWaalsContact C-N 3.26Å; S189-T191 PolarHBondContact O-N 3.43Å; S189-K192 PolarHBondContact O-N 3.07Å; S189-A193 PolarHBondContact O-N 2.87Å; S189-A193 VanDerWaalsContact O-N 3.16Å
190	R	81.6	Confident	79.9	Confident	149 Å²	149	80.3 Å²	80.3	56%	0.562	42%	0.418	S	S	*	.	H	α-helix	trans	-50.1	-47.1	175.3	-176.3	173.8	175.5	173.7	2.1	111.3	Y112 K192 A193 F194	Y112-R190 HydrophobicContact CE2-CG 3.89Å; R190-K192 VanDerWaalsContact C-N 3.28Å; R190-K192 PolarHBondContact O-N 3.48Å; R190-A193 WeakPolarHBondContact O-CB 3.28Å; R190-A193 PolarHBondContact O-N 2.95Å; R190-A193 VanDerWaalsContact O-N 3.11Å; R190-F194 HydrophobicContact CG-CD2 3.76Å; R190-F194 HydrophobicContact CG-CE2 3.54Å; R190-F194 VanDerWaalsContact O-CD2 3.26Å; R190-F194 WeakPolarHBondContact O-CD2 3.46Å; R190-F194 PolarHBondContact O-N 3.45Å
191	T	85.5	Confident	80.8	Confident	110 Å²	110	79.5 Å²	79.5	68%	0.675	41%	0.409	S	S	*	.	H	α-helix	trans	-58.5	-38.8	-179.8	-47.3	0	0	0	0	112.6	S189 F194 A195	S189-T191 VanDerWaalsContact C-N 3.26Å; S189-T191 PolarHBondContact O-N 3.43Å; T191-F194 PolarHBondContact O-N 2.94Å; T191-A195 PolarHBondContact O-N 3.24Å
192	K	85.4	Confident	82.1	Confident	85 Å²	85	80 Å²	80	37%	0.37	41%	0.41	S	S	.	.	H	α-helix	trans	-70.8	-36.6	178.6	-66	179.1	178.9	177.2	0	111.6	F187 S189 R190 A195 K196	F187-K192 HydrophobicContact CD1-CD 4.12Å; F187-K192 WeakPolarHBondContact O-CD 3.38Å; S189-K192 PolarHBondContact O-N 3.07Å; R190-K192 VanDerWaalsContact C-N 3.28Å; R190-K192 PolarHBondContact O-N 3.48Å; K192-A195 PolarHBondContact O-N 3.01Å; K192-K196 WeakPolarHBondContact O-CG 3.42Å; K192-K196 PolarHBondContact O-N 3.09Å
193	A	88.4	Confident	83.5	Confident	5 Å²	5	76.7 Å²	76.7	4%	0.041	39%	0.394	C	S	.	.	H	α-helix	trans	-62.7	-45.1	173.5	0	0	0	0	0	111.4	A109 S189 R190 A195 K196 I197	A109-A193 HydrophobicContact CB-CB 3.97Å; S189-A193 PolarHBondContact O-N 2.87Å; S189-A193 VanDerWaalsContact O-N 3.16Å; R190-A193 WeakPolarHBondContact O-CB 3.28Å; R190-A193 PolarHBondContact O-N 2.95Å; R190-A193 VanDerWaalsContact O-N 3.11Å; A193-A195 PolarHBondContact O-N 3.41Å; A193-K196 PolarHBondContact O-N 3.47Å; A193-I197 WeakPolarHBondContact O-CG1 3.47Å; A193-I197 PolarHBondContact O-N 3.5Å
194	F	91.3	Very high	85	Confident	75 Å²	75	72.2 Å²	72.2	33%	0.329	37%	0.373	S	S	.	.	H	α-helix	trans	-61.2	-41.4	174.5	-81.7	-79	0	0	0	112.5	Y112 R190 T191 K196 I197 I198	Y112-F194 HydrophobicContact CD1-CZ 4.41Å; R190-F194 HydrophobicContact CG-CD2 3.76Å; R190-F194 HydrophobicContact CG-CE2 3.54Å; R190-F194 VanDerWaalsContact O-CD2 3.26Å; R190-F194 WeakPolarHBondContact O-CD2 3.46Å; R190-F194 PolarHBondContact O-N 3.45Å; T191-F194 PolarHBondContact O-N 2.94Å; F194-K196 VanDerWaalsContact C-N 3.34Å; F194-K196 PolarHBondContact O-N 3.28Å; F194-I197 PolarHBondContact O-N 3.05Å; F194-I198 WeakPolarHBondContact O-CG1 3.44Å; F194-I198 PolarHBondContact O-N 3.45Å
195	A	92.2	Very high	86.6	Confident	58 Å²	58	73.5 Å²	73.5	48%	0.479	38%	0.383	S	S	.	.	H	α-helix	trans	-60.2	-42.5	175.4	0	0	0	0	0	112.4	T191 K192 A193 I198 A199	T191-A195 PolarHBondContact O-N 3.24Å; K192-A195 PolarHBondContact O-N 3.01Å; A193-A195 PolarHBondContact O-N 3.41Å; A195-I198 PolarHBondContact O-N 3.01Å; A195-A199 PolarHBondContact O-N 3.5Å
196	K	92.1	Very high	88.1	Confident	95 Å²	95	71.2 Å²	71.2	41%	0.413	37%	0.374	S	S	.	.	H	α-helix	trans	-63.8	-41	174.4	-67.8	178.9	-175.6	-175.1	0	112.1	F113 D173 K192 A193 F194 A199 V200	F113-K196 HydrophobicContact CE1-CB 4.14Å; F113-K196 HydrophobicContact CE2-CD 4.29Å; F113-K196 HydrophobicContact CZ-CB 3.52Å; F113-K196 HydrophobicContact CZ-CD 3.78Å; F113-K196 HydrophobicContact CZ-CG 4.34Å; D173-K196 IonicContact OD1-NZ 3.76Å; D173-K196 PolarHBondContact OD1-NZ 3.32Å; K192-K196 WeakPolarHBondContact O-CG 3.42Å; K192-K196 PolarHBondContact O-N 3.09Å; A193-K196 PolarHBondContact O-N 3.47Å; F194-K196 VanDerWaalsContact C-N 3.34Å; F194-K196 PolarHBondContact O-N 3.28Å; K196-A199 WeakPolarHBondContact O-CB 3.48Å; K196-A199 PolarHBondContact O-N 3.41Å; K196-V200 WeakPolarHBondContact O-CG2 3.31Å; K196-V200 PolarHBondContact O-N 2.98Å
197	I	96.4	Very high	89.8	Confident	14 Å²	14	64.1 Å²	64.1	7%	0.072	35%	0.35	C	S	.	.	H	α-helix	trans	-62.2	-46.9	177.1	-70.9	165.8	0	0	0	110.6	F113 S116 A193 F194 A199 V200 W201	F113-I197 HydrophobicContact CD1-CG1 3.86Å; F113-I197 HydrophobicContact CE1-CG1 3.88Å; F113-I197 HydrophobicContact CG-CG1 4.27Å; F113-I197 HydrophobicContact CZ-CG1 4.32Å; S116-I197 VanDerWaalsContact OG-CG2 3.28Å; S116-I197 WeakPolarHBondContact OG-CG2 3.25Å; A193-I197 WeakPolarHBondContact O-CG1 3.47Å; A193-I197 PolarHBondContact O-N 3.5Å; F194-I197 PolarHBondContact O-N 3.05Å; I197-A199 VanDerWaalsContact C-N 3.29Å; I197-A199 PolarHBondContact O-N 3.5Å; I197-V200 WeakPolarHBondContact O-CB 3.09Å; I197-V200 PolarHBondContact O-N 3.15Å; I197-V200 VanDerWaalsContact O-N 3.15Å; I197-W201 VanDerWaalsContact O-CD1 3.3Å; I197-W201 PolarHBondContact O-N 3.31Å
198	I	96.9	Very high	91.5	Very high	106 Å²	106	60.4 Å²	60.4	54%	0.544	33%	0.334	S	S	.	.	H	α-helix	trans	-58	-45.3	176.2	-68	165.5	0	0	0	110	F194 A195 V200 W201 T202	F194-I198 WeakPolarHBondContact O-CG1 3.44Å; F194-I198 PolarHBondContact O-N 3.45Å; A195-I198 PolarHBondContact O-N 3.01Å; I198-V200 VanDerWaalsContact C-N 3.32Å; I198-V200 PolarHBondContact O-N 2.97Å; I198-W201 PolarHBondContact O-N 2.99Å; I198-T202 PolarHBondContact O-N 2.94Å; I198-T202 PolarHBondContact O-OG1 3.23Å
199	A	96.2	Very high	93	Very high	48 Å²	48	60.9 Å²	60.9	40%	0.397	33%	0.334	S	S	.	.	H	α-helix	trans	-59.2	-41.7	177	0	0	0	0	0	112.5	A195 K196 I197 T202 I203	A195-A199 PolarHBondContact O-N 3.5Å; K196-A199 WeakPolarHBondContact O-CB 3.48Å; K196-A199 PolarHBondContact O-N 3.41Å; I197-A199 VanDerWaalsContact C-N 3.29Å; I197-A199 PolarHBondContact O-N 3.5Å; A199-T202 PolarHBondContact O-N 3.15Å; A199-I203 WeakPolarHBondContact O-CD1 3.46Å; A199-I203 VanDerWaalsContact O-CG1 3.22Å; A199-I203 WeakPolarHBondContact O-CG1 3.5Å; A199-I203 PolarHBondContact O-N 2.88Å
200	V	97.1	Very high	93.7	Very high	11 Å²	11	60.5 Å²	60.5	7%	0.067	33%	0.331	C	S	.	.	H	α-helix	trans	-59	-49.3	174.8	168.6	0	0	0	0	110.9	M165 H166 A169 K196 I197 I198 T202 I203 S204	M165-V200 HydrophobicContact CB-CG1 3.72Å; H166-V200 VanDerWaalsContact CE1-CG1 3.45Å; H166-V200 WeakPolarHBondContact CE1-CG1 3.22Å; H166-V200 WeakPolarHBondContact ND1-CG1 3.44Å; A169-V200 HydrophobicContact CB-CG2 3.93Å; K196-V200 WeakPolarHBondContact O-CG2 3.31Å; K196-V200 PolarHBondContact O-N 2.98Å; I197-V200 WeakPolarHBondContact O-CB 3.09Å; I197-V200 PolarHBondContact O-N 3.15Å; I197-V200 VanDerWaalsContact O-N 3.15Å; I198-V200 VanDerWaalsContact C-N 3.32Å; I198-V200 PolarHBondContact O-N 2.97Å; V200-T202 PolarHBondContact O-N 2.94Å; V200-I203 PolarHBondContact O-N 3.3Å; V200-S204 PolarHBondContact O-N 3.08Å; V200-S204 PolarHBondContact O-OG 3.3Å; V200-S204 VanDerWaalsContact O-OG 3.07Å
201	W	98.4	Very high	94.3	Very high	59 Å²	59	54 Å²	54	22%	0.223	31%	0.307	C	S	.	.	H	α-helix	trans	-61.2	-43	177.2	-81.1	102.3	0	0	0	112.7	S116 A120 L123 F159 A162 H166 I197 I198 I203 S204 V205	S116-W201 PolarHBondContact OG-NE1 3.42Å; A120-W201 HydrophobicContact CB-CH2 3.91Å; A120-W201 HydrophobicContact CB-CZ2 4.03Å; L123-W201 HydrophobicContact CD1-CH2 4.4Å; F159-W201 AromaticContact CD1-CH2 3.98Å; F159-W201 HydrophobicContact CD1-CH2 3.98Å; F159-W201 AromaticContact CD1-CZ3 3.99Å; F159-W201 HydrophobicContact CD1-CZ3 3.99Å; F159-W201 HydrophobicContact CE1-CH2 4.12Å; F159-W201 HydrophobicContact CE1-CZ3 4.04Å; A162-W201 HydrophobicContact CB-CE3 4.25Å; A162-W201 HydrophobicContact CB-CH2 4.19Å; A162-W201 HydrophobicContact CB-CZ3 4Å; H166-W201 AromaticContact CE1-CE2 3.98Å; H166-W201 AromaticContact CE1-NE1 3.59Å; H166-W201 AromaticContact NE2-NE1 3.8Å; I197-W201 VanDerWaalsContact O-CD1 3.3Å; I197-W201 PolarHBondContact O-N 3.31Å; I198-W201 PolarHBondContact O-N 2.99Å; W201-I203 VanDerWaalsContact C-N 3.33Å; W201-I203 PolarHBondContact O-N 3.1Å; W201-S204 PolarHBondContact O-N 3.45Å; W201-V205 WeakPolarHBondContact O-CG2 3.46Å; W201-V205 PolarHBondContact O-N 3.26Å
202	T	97.9	Very high	94.7	Very high	89 Å²	89	49.5 Å²	49.5	55%	0.546	28%	0.279	S	S	.	.	H	α-helix	trans	-61.1	-42.4	177	-56.5	0	0	0	0	111.6	I198 A199 V200 V205 G206	I198-T202 PolarHBondContact O-N 2.94Å; I198-T202 PolarHBondContact O-OG1 3.23Å; A199-T202 PolarHBondContact O-N 3.15Å; V200-T202 PolarHBondContact O-N 2.94Å; T202-V205 PolarHBondContact O-N 3.43Å; T202-G206 PolarHBondContact O-N 3.3Å
203	I	96.4	Very high	95.2	Very high	82 Å²	82	48.1 Å²	48.1	42%	0.421	28%	0.278	S	S	.	.	H	α-helix	trans	-63.8	-45.9	176.3	-67	162.4	0	0	0	110.3	M165 A199 V200 W201 V205 G206 I207	M165-I203 HydrophobicContact CE-CD1 4.46Å; M165-I203 HydrophobicContact CE-CG2 3.83Å; A199-I203 WeakPolarHBondContact O-CD1 3.46Å; A199-I203 VanDerWaalsContact O-CG1 3.22Å; A199-I203 WeakPolarHBondContact O-CG1 3.5Å; A199-I203 PolarHBondContact O-N 2.88Å; V200-I203 PolarHBondContact O-N 3.3Å; W201-I203 VanDerWaalsContact C-N 3.33Å; W201-I203 PolarHBondContact O-N 3.1Å; I203-V205 PolarHBondContact O-N 3.08Å; I203-G206 PolarHBondContact O-N 2.9Å; I203-I207 HydrophobicContact CG2-CD1 3.71Å; I203-I207 HydrophobicContact CG2-CG1 4.34Å; I203-I207 VanDerWaalsContact O-CG1 3.32Å; I203-I207 WeakPolarHBondContact O-CG1 3.42Å; I203-I207 PolarHBondContact O-N 3.43Å
204	S	97.9	Very high	95.4	Very high	0 Å²	0	52.4 Å²	52.4	0%	0	30%	0.296	C	S	.	.	H	α-helix	trans	-61.4	-44.4	178.2	-58	0	0	0	0	112.3	A162 V200 W201 G206 I207 S208	A162-S204 VanDerWaalsContact CA-OG 3.25Å; A162-S204 WeakPolarHBondContact CA-OG 3.47Å; A162-S204 PolarHBondContact N-OG 3.41Å; V200-S204 PolarHBondContact O-N 3.08Å; V200-S204 PolarHBondContact O-OG 3.3Å; V200-S204 VanDerWaalsContact O-OG 3.07Å; W201-S204 PolarHBondContact O-N 3.45Å; S204-G206 VanDerWaalsContact C-N 3.33Å; S204-G206 PolarHBondContact O-N 3.18Å; S204-I207 PolarHBondContact O-N 2.98Å; S204-S208 PolarHBondContact O-N 3.15Å; S204-S208 PolarHBondContact O-OG 3.38Å; S204-S208 VanDerWaalsContact O-OG 3.08Å
205	V	97.9	Very high	95.4	Very high	56 Å²	56	48.9 Å²	48.9	34%	0.339	28%	0.281	S	S	.	.	H	α-helix	trans	-59	-45.8	173.4	170.2	0	0	0	0	110.9	L158 W201 T202 I203 I207 S208 M209	L158-V205 HydrophobicContact CD1-CB 4.35Å; L158-V205 HydrophobicContact CD1-CG2 3.66Å; L158-V205 HydrophobicContact CD2-CG2 4.46Å; W201-V205 WeakPolarHBondContact O-CG2 3.46Å; W201-V205 PolarHBondContact O-N 3.26Å; T202-V205 PolarHBondContact O-N 3.43Å; I203-V205 PolarHBondContact O-N 3.08Å; V205-I207 VanDerWaalsContact C-N 3.35Å; V205-I207 PolarHBondContact O-N 2.86Å; V205-S208 PolarHBondContact O-N 3.25Å; V205-M209 VanDerWaalsContact O-CB 3.31Å; V205-M209 WeakPolarHBondContact O-CB 3.26Å; V205-M209 PolarHBondContact O-N 2.93Å
206	G	96.5	Very high	95.4	Very high	47 Å²	47	49.6 Å²	49.6	49%	0.485	28%	0.276	S	S	.	.	H	α-helix	trans	-60.3	-41.6	178.4	0	0	0	0	0	113.3	T202 I203 S204	T202-G206 PolarHBondContact O-N 3.3Å; I203-G206 PolarHBondContact O-N 2.9Å; S204-G206 VanDerWaalsContact C-N 3.33Å; S204-G206 PolarHBondContact O-N 3.18Å
207	I	94.9	Very high	95.4	Very high	41 Å²	41	52.4 Å²	52.4	21%	0.21	29%	0.291	C	S	.	.	H	α-helix	trans	-66.4	-39.5	177.8	-67.9	168	0	0	0	111.2	T161 I203 S204 V205 P210 V242 A243	T161-I207 HydrophobicContact CG2-CB 4.29Å; T161-I207 HydrophobicContact CG2-CD1 3.92Å; T161-I207 HydrophobicContact CG2-CG2 4.18Å; I203-I207 HydrophobicContact CG2-CD1 3.71Å; I203-I207 HydrophobicContact CG2-CG1 4.34Å; I203-I207 VanDerWaalsContact O-CG1 3.32Å; I203-I207 WeakPolarHBondContact O-CG1 3.42Å; I203-I207 PolarHBondContact O-N 3.43Å; S204-I207 PolarHBondContact O-N 2.98Å; V205-I207 VanDerWaalsContact C-N 3.35Å; V205-I207 PolarHBondContact O-N 2.86Å; I207-P210 WeakPolarHBondContact O-CD 3.41Å; I207-V242 HydrophobicContact CD1-CG1 3.89Å; I207-V242 HydrophobicContact CG1-CG1 3.78Å; I207-V242 HydrophobicContact CG2-CG1 3.96Å; I207-A243 HydrophobicContact CG2-CB 4.08Å
208	S	95.8	Very high	95.2	Very high	0 Å²	0	54.8 Å²	54.8	0%	0	30%	0.304	C	S	.	.	H	α-helix	trans	-85.1	-19.1	-176.6	-51.1	0	0	0	0	113.9	Y154 L158 S204 V205 I211 P212	Y154-S208 WeakPolarHBondContact CD2-O 3.36Å; L158-S208 VanDerWaalsContact CA-OG 3.25Å; L158-S208 WeakPolarHBondContact CA-OG 3.47Å; L158-S208 PolarHBondContact N-OG 3.02Å; S204-S208 PolarHBondContact O-N 3.15Å; S204-S208 PolarHBondContact O-OG 3.38Å; S204-S208 VanDerWaalsContact O-OG 3.08Å; V205-S208 PolarHBondContact O-N 3.25Å; S208-I211 WeakPolarHBondContact O-CB 3.48Å; S208-I211 PolarHBondContact O-N 3.16Å; S208-P212 WeakPolarHBondContact O-CD 3.31Å
209	M	95.6	Very high	95	Very high	92 Å²	92	52.7 Å²	52.7	45%	0.453	29%	0.294	S	S	.	.	T	Hydrogen-bonded Turn	trans	-58.8	-31	-174.4	-168.4	58	-173.3	0	0	116.3	V205 I211 P212 V213	V205-M209 VanDerWaalsContact O-CB 3.31Å; V205-M209 WeakPolarHBondContact O-CB 3.26Å; V205-M209 PolarHBondContact O-N 2.93Å; M209-I211 PolarHBondContact O-N 2.96Å; M209-P212 WeakPolarHBondContact O-CD 3.41Å; M209-P212 VanDerWaalsContact O-CG 3.31Å; M209-P212 WeakPolarHBondContact O-CG 3.19Å; M209-P212 HydrophobicContact SD-CG 4.05Å; M209-V213 HydrophobicContact CE-CG2 3.83Å; M209-V213 HydrophobicContact CG-CG2 4.3Å; M209-V213 WeakPolarHBondContact O-CG2 3.15Å; M209-V213 PolarHBondContact O-N 3.45Å
210	P	94.3	Very high	94.7	Very high	49 Å²	49	53.9 Å²	53.9	32%	0.318	30%	0.299	S	S	.	.	H	α-helix	trans	-57.9	-34.4	175.3	-27.9	37.2	0	0	0	113.5	I207 V213 F214 F235	I207-P210 WeakPolarHBondContact O-CD 3.41Å; P210-V213 PolarHBondContact O-N 3.39Å; P210-F214 HydrophobicContact CB-CD2 4.07Å; P210-F214 HydrophobicContact CB-CE2 4.17Å; P210-F214 WeakPolarHBondContact O-CD2 3.46Å; P210-F214 PolarHBondContact O-N 2.88Å; P210-F235 HydrophobicContact CB-CE1 4.09Å
211	I	93.3	Very high	94.4	Very high	12 Å²	12	56.3 Å²	56.3	6%	0.062	31%	0.308	C	S	.	.	H	α-helix	trans	-57.6	-55.2	-176.4	-63.8	160.6	0	0	0	112.3	I153 V157 S208 M209 G215	I153-I211 HydrophobicContact CB-CG2 4.11Å; I153-I211 HydrophobicContact CG2-CD1 4.45Å; I153-I211 HydrophobicContact CG2-CG2 3.77Å; V157-I211 HydrophobicContact CB-CD1 3.68Å; V157-I211 HydrophobicContact CG1-CD1 3.81Å; V157-I211 HydrophobicContact CG2-CD1 3.62Å; S208-I211 WeakPolarHBondContact O-CB 3.48Å; S208-I211 PolarHBondContact O-N 3.16Å; M209-I211 PolarHBondContact O-N 2.96Å; I211-G215 VanDerWaalsContact O-CA 3.29Å; I211-G215 WeakPolarHBondContact O-CA 3.25Å; I211-G215 PolarHBondContact O-N 2.92Å
212	P	94.4	Very high	94.2	Very high	15 Å²	15	53.6 Å²	53.6	10%	0.097	30%	0.298	C	S	.	.	H	α-helix	trans	-69.8	-32	178.1	26.8	-35.2	0	0	0	112.4	Y154 S208 M209 L216	Y154-P212 HydrophobicContact CD2-CG 3.67Å; Y154-P212 HydrophobicContact CE2-CG 4.2Å; Y154-P212 HydrophobicContact CG-CG 3.96Å; S208-P212 WeakPolarHBondContact O-CD 3.31Å; M209-P212 WeakPolarHBondContact O-CD 3.41Å; M209-P212 VanDerWaalsContact O-CG 3.31Å; M209-P212 WeakPolarHBondContact O-CG 3.19Å; M209-P212 HydrophobicContact SD-CG 4.05Å; P212-L216 HydrophobicContact CB-CD1 4.32Å; P212-L216 WeakPolarHBondContact O-CB 3.12Å; P212-L216 WeakPolarHBondContact O-CD1 3.47Å; P212-L216 WeakPolarHBondContact O-CG 3.3Å; P212-L216 PolarHBondContact O-N 2.96Å
213	V	94.7	Very high	94	Very high	57 Å²	57	51.3 Å²	51.3	35%	0.345	28%	0.281	S	S	.	.	H	α-helix	trans	-61.7	-50.5	178.6	172.1	0	0	0	0	110.9	M209 P210 Q217	M209-V213 HydrophobicContact CE-CG2 3.83Å; M209-V213 HydrophobicContact CG-CG2 4.3Å; M209-V213 WeakPolarHBondContact O-CG2 3.15Å; M209-V213 PolarHBondContact O-N 3.45Å; P210-V213 PolarHBondContact O-N 3.39Å; V213-Q217 VanDerWaalsContact O-CG 3.28Å; V213-Q217 WeakPolarHBondContact O-CG 3.36Å
214	F	92.9	Very high	93.6	Very high	95 Å²	95	51.6 Å²	51.6	42%	0.417	28%	0.279	S	S	.	.	H	α-helix	trans	-83.5	-37.2	-178.6	-66.2	-71.4	0	0	0	112.3	P210 L216 Q217 D218 F235	P210-F214 HydrophobicContact CB-CD2 4.07Å; P210-F214 HydrophobicContact CB-CE2 4.17Å; P210-F214 WeakPolarHBondContact O-CD2 3.46Å; P210-F214 PolarHBondContact O-N 2.88Å; F214-L216 PolarHBondContact O-N 2.9Å; F214-Q217 PolarHBondContact O-N 2.92Å; F214-D218 PolarHBondContact O-N 3.05Å; F214-F235 HydrophobicContact CB-CE2 3.86Å; F214-F235 HydrophobicContact CB-CZ 3.73Å; F214-F235 HydrophobicContact CD1-CZ 4.46Å; F214-F235 AromaticContact CD2-CE1 3.81Å; F214-F235 HydrophobicContact CD2-CE1 3.81Å; F214-F235 HydrophobicContact CD2-CE2 4.26Å; F214-F235 AromaticContact CD2-CZ 3.28Å; F214-F235 HydrophobicContact CD2-CZ 3.28Å; F214-F235 HydrophobicContact CE2-CE1 4.26Å; F214-F235 AromaticContact CE2-CZ 3.98Å; F214-F235 HydrophobicContact CE2-CZ 3.98Å; F214-F235 HydrophobicContact CG-CE2 4.19Å; F214-F235 AromaticContact CG-CZ 3.57Å; F214-F235 HydrophobicContact CG-CZ 3.57Å
215	G	91.6	Very high	93	Very high	1 Å²	1	59.4 Å²	59.4	1%	0.01	31%	0.313	C	S	.	.	H	α-helix	trans	-73.6	-21.2	-178.3	0	0	0	0	0	115.1	I211	I211-G215 VanDerWaalsContact O-CA 3.29Å; I211-G215 WeakPolarHBondContact O-CA 3.25Å; I211-G215 PolarHBondContact O-N 2.92Å
216	L	92.3	Very high	92.5	Very high	72 Å²	72	62.8 Å²	62.8	38%	0.377	33%	0.329	S	S	.	.	H	α-helix	trans	-84.5	-24.1	171.1	-65.7	173.1	0	0	0	112.6	K147 A150 P212 F214	K147-L216 HydrophobicContact CB-CD2 4Å; K147-L216 HydrophobicContact CD-CD2 3.76Å; K147-L216 HydrophobicContact CG-CD2 4.41Å; K147-L216 PolarHBondContact NZ-O 3.11Å; A150-L216 HydrophobicContact CB-CD2 3.9Å; A150-L216 HydrophobicContact CB-CG 4.17Å; P212-L216 HydrophobicContact CB-CD1 4.32Å; P212-L216 WeakPolarHBondContact O-CB 3.12Å; P212-L216 WeakPolarHBondContact O-CD1 3.47Å; P212-L216 WeakPolarHBondContact O-CG 3.3Å; P212-L216 PolarHBondContact O-N 2.96Å; F214-L216 PolarHBondContact O-N 2.9Å
217	Q	92.6	Very high	92.2	Very high	155 Å²	155	62 Å²	62	72%	0.724	32%	0.317	S	S	*	.	H	α-helix	trans	-83.5	-42.2	176.7	-71.6	179.6	8.7	0	0	111.9	V213 F214	V213-Q217 VanDerWaalsContact O-CG 3.28Å; V213-Q217 WeakPolarHBondContact O-CG 3.36Å; F214-Q217 PolarHBondContact O-N 2.92Å
218	D	92.4	Very high	92.2	Very high	64 Å²	64	60.8 Å²	60.8	34%	0.342	31%	0.312	S	S	.	.			trans	-126.8	100.4	-176.7	-176	-0.6	0	0	0	110	F214 S220 K221	F214-D218 PolarHBondContact O-N 3.05Å; D218-S220 PolarHBondContact O-N 3.25Å; D218-S220 VanDerWaalsContact OD1-CB 3.27Å; D218-S220 WeakPolarHBondContact OD1-CB 3.34Å; D218-S220 PolarHBondContact OD1-N 2.89Å; D218-S220 PolarHBondContact OD1-OG 3.31Å; D218-S220 PolarHBondContact OD2-OG 3.49Å; D218-K221 HydrophobicContact CB-CG 3.92Å; D218-K221 WeakPolarHBondContact O-CB 3.28Å; D218-K221 PolarHBondContact O-N 3.49Å; D218-K221 VanDerWaalsContact OD2-CE 3.29Å; D218-K221 WeakPolarHBondContact OD2-CE 3.13Å
219	D	91	Very high	92	Very high	62 Å²	62	64.1 Å²	64.1	33%	0.332	33%	0.329	S	S	.	.	G	3₁₀ helix	trans	-63.9	-21.6	-178.5	-63.2	-20.2	0	0	0	111.3	K147 K221 V222 F223	K147-D219 IonicContact NZ-OD1 3.9Å; K147-D219 PolarHBondContact NZ-OD1 2.95Å; K147-D219 IonicContact NZ-OD2 2.76Å; D219-K221 PolarHBondContact O-N 2.97Å; D219-V222 WeakPolarHBondContact O-CG2 3.33Å; D219-V222 PolarHBondContact O-N 3.43Å; D219-F223 HydrophobicContact CB-CD2 4.31Å; D219-F223 WeakPolarHBondContact O-CD2 3.45Å; D219-F223 PolarHBondContact O-N 2.82Å; D219-F223 VanDerWaalsContact O-N 3.14Å
220	S	91.2	Very high	91.8	Very high	73 Å²	73	61.7 Å²	61.7	51%	0.51	32%	0.318	S	S	.	.	G	3₁₀ helix	trans	-67.2	-18.7	177.9	76.1	0	0	0	0	113.7	D218	D218-S220 PolarHBondContact O-N 3.25Å; D218-S220 VanDerWaalsContact OD1-CB 3.27Å; D218-S220 WeakPolarHBondContact OD1-CB 3.34Å; D218-S220 PolarHBondContact OD1-N 2.89Å; D218-S220 PolarHBondContact OD1-OG 3.31Å; D218-S220 PolarHBondContact OD2-OG 3.49Å
221	K	91.3	Very high	91.5	Very high	61 Å²	61	61.1 Å²	61.1	27%	0.265	32%	0.317	S	S	.	.	G	3₁₀ helix	trans	-78.8	-20.7	178.5	-58.2	-66.5	177.2	-174.2	0	113.1	D218 D219 A231 D232	D218-K221 HydrophobicContact CB-CG 3.92Å; D218-K221 WeakPolarHBondContact O-CB 3.28Å; D218-K221 PolarHBondContact O-N 3.49Å; D218-K221 VanDerWaalsContact OD2-CE 3.29Å; D218-K221 WeakPolarHBondContact OD2-CE 3.13Å; D219-K221 PolarHBondContact O-N 2.97Å; K221-A231 PolarHBondContact O-N 3.29Å; K221-D232 HydrophobicContact CD-CB 3.75Å; K221-D232 VanDerWaalsContact CD-OD2 3.3Å; K221-D232 WeakPolarHBondContact CD-OD2 3.37Å; K221-D232 WeakPolarHBondContact CE-OD2 3.25Å; K221-D232 IonicContact NZ-OD2 3.7Å; K221-D232 PolarHBondContact NZ-OD2 3.25Å
222	V	93.1	Very high	91.4	Very high	2 Å²	2	61.5 Å²	61.5	1%	0.012	32%	0.319	C	S	.	.	T	Hydrogen-bonded Turn	trans	-118.9	-4.2	-174.4	-64.6	0	0	0	0	113.6	C149 A150 I153 D219 L229	C149-V222 PolarHBondContact SG-O 3.43Å; A150-V222 HydrophobicContact CB-CG1 4.25Å; I153-V222 HydrophobicContact CD1-CB 3.94Å; I153-V222 HydrophobicContact CD1-CG1 4.06Å; D219-V222 WeakPolarHBondContact O-CG2 3.33Å; D219-V222 PolarHBondContact O-N 3.43Å; V222-L229 CarbonylContact C-O 3.04Å; V222-L229 WeakPolarHBondContact CA-O 3.1Å; V222-L229 PolarHBondContact O-N 3.45Å
223	F	93.7	Very high	91.2	Very high	41 Å²	41	64.6 Å²	64.6	18%	0.18	33%	0.332	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-123.3	132.4	176.6	-75.8	-76.3	0	0	0	112.2	W142 T146 C149 D219 S227 C228	W142-F223 HydrophobicContact CB-CE1 3.79Å; W142-F223 AromaticContact CD1-CE1 3.79Å; W142-F223 AromaticContact CD1-CZ 3.74Å; W142-F223 AromaticContact CG-CE1 3.83Å; W142-F223 HydrophobicContact CG-CE1 3.83Å; W142-F223 HydrophobicContact CG-CZ 4.18Å; T146-F223 HydrophobicContact CG2-CE2 4.38Å; T146-F223 HydrophobicContact CG2-CZ 4.4Å; C149-F223 HydrophobicContact CB-CE1 4.1Å; C149-F223 HydrophobicContact CB-CE2 3.83Å; C149-F223 HydrophobicContact CB-CZ 3.4Å; C149-F223 VanDerWaalsContact CB-CZ 3.4Å; D219-F223 HydrophobicContact CB-CD2 4.31Å; D219-F223 WeakPolarHBondContact O-CD2 3.45Å; D219-F223 PolarHBondContact O-N 2.82Å; D219-F223 VanDerWaalsContact O-N 3.14Å; F223-S227 WeakPolarHBondContact CA-O 3.12Å; F223-C228 HydrophobicContact CE1-CB 4.17Å
224	K	88.8	Confident	91.1	Very high	89 Å²	89	66.9 Å²	66.9	39%	0.387	34%	0.343	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-129.1	115.3	167.3	-174.8	177.9	-178.4	-179.9	0	108.5	D226 S227 L229 A231 E355	K224-D226 PolarHBondContact O-N 3.18Å; K224-S227 PolarHBondContact N-O 3.31Å; K224-S227 WeakPolarHBondContact O-CB 3.24Å; K224-S227 PolarHBondContact O-N 3.08Å; K224-L229 HydrophobicContact CB-CD1 3.76Å; K224-L229 HydrophobicContact CB-CD2 4.15Å; K224-L229 HydrophobicContact CB-CG 4.01Å; K224-L229 HydrophobicContact CD-CD1 4.3Å; K224-A231 HydrophobicContact CB-CB 4.28Å; K224-E355 IonicContact NZ-OE1 2.86Å; K224-E355 PolarHBondContact NZ-OE1 3.26Å; K224-E355 IonicContact NZ-OE2 3.76Å
225	K	85	Confident	91	Very high	163 Å²	163	64.4 Å²	64.4	71%	0.709	33%	0.332	S	S	*	.	T	Hydrogen-bonded Turn	trans	49.4	50.9	179.6	-59	175.8	-179.4	168.9	0	112.7	S227 E355	K225-S227 PolarHBondContact O-N 3.04Å; K225-E355 IonicContact NZ-OE2 2.7Å
226	D	87.4	Confident	91	Very high	127 Å²	127	64.7 Å²	64.7	68%	0.679	33%	0.333	S	S	*	.	T	Hydrogen-bonded Turn	trans	63.4	3	-177.5	-54.2	-44.9	0	0	0	116.8	W142 K224	W142-D226 PolarHBondContact N-O 2.76Å; K224-D226 PolarHBondContact O-N 3.18Å
227	S	90.8	Very high	91.1	Very high	32 Å²	32	63.7 Å²	63.7	22%	0.224	33%	0.328	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-87.9	135.8	167.6	-61.5	0	0	0	0	111.1	Y140 F223 K224 K225 L229	Y140-S227 WeakPolarHBondContact O-CA 3.32Å; Y140-S227 WeakPolarHBondContact O-CB 2.99Å; Y140-S227 PolarHBondContact O-OG 2.92Å; F223-S227 WeakPolarHBondContact CA-O 3.12Å; K224-S227 PolarHBondContact N-O 3.31Å; K224-S227 WeakPolarHBondContact O-CB 3.24Å; K224-S227 PolarHBondContact O-N 3.08Å; K225-S227 PolarHBondContact O-N 3.04Å; S227-L229 PolarHBondContact O-N 3.39Å
228	C	94.1	Very high	91.1	Very high	15 Å²	15	61.5 Å²	61.5	10%	0.101	32%	0.32	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-80.7	103.9	173.6	178.3	0	0	0	0	110.1	W142 C149 W152 F223	W142-C228 HydrophobicContact CB-CB 4.01Å; W142-C228 HydrophobicContact CD2-CB 3.56Å; W142-C228 HydrophobicContact CE3-CB 3.25Å; W142-C228 HydrophobicContact CG-CB 3.9Å; W142-C228 HydrophobicContact CZ3-CB 3.92Å; C149-C228 WeakPolarHBondContact CA-SG 3.42Å; C149-C228 HydrophobicContact CB-CB 3.91Å; C149-C228 WeakPolarHBondContact CB-SG 3.34Å; C149-C228 VanDerWaalsContact SG-CA 3.5Å; C149-C228 WeakPolarHBondContact SG-CB 3.45Å; C149-C228 CovalentContact SG-SG 2.02Å; C149-C228 PolarHBondContact SG-SG 3.45Å; W152-C228 VanDerWaalsContact CE3-SG 3.52Å; W152-C228 HydrophobicContact CZ3-CB 4.44Å; F223-C228 HydrophobicContact CE1-CB 4.17Å
229	L	91.6	Very high	91	Very high	69 Å²	69	59.8 Å²	59.8	36%	0.361	32%	0.318	S	S	.	.	S	Bend	trans	-154.9	154.9	178.4	63.3	85.9	0	0	0	110.4	V222 K224 S227 A231	V222-L229 CarbonylContact C-O 3.04Å; V222-L229 WeakPolarHBondContact CA-O 3.1Å; V222-L229 PolarHBondContact O-N 3.45Å; K224-L229 HydrophobicContact CB-CD1 3.76Å; K224-L229 HydrophobicContact CB-CD2 4.15Å; K224-L229 HydrophobicContact CB-CG 4.01Å; K224-L229 HydrophobicContact CD-CD1 4.3Å; S227-L229 PolarHBondContact O-N 3.39Å; L229-A231 HydrophobicContact CD1-CB 4.08Å; L229-A231 PolarHBondContact O-N 3.34Å
230	L	91.7	Very high	91.2	Very high	41 Å²	41	57 Å²	57	22%	0.215	30%	0.304	C	S	.	.			trans	-71.2	100.8	177.3	-168.6	67.9	0	0	0	109.5	I153 F235 V236	I153-L230 HydrophobicContact CG2-CB 4.41Å; I153-L230 HydrophobicContact CG2-CD1 4.46Å; L230-F235 HydrophobicContact CD1-CB 4.04Å; L230-F235 HydrophobicContact CD1-CD2 4.49Å; L230-F235 HydrophobicContact CD2-CB 3.93Å; L230-F235 HydrophobicContact CG-CB 4.1Å; L230-V236 HydrophobicContact CB-CG2 4.35Å; L230-V236 HydrophobicContact CD2-CG2 4.06Å; L230-V236 HydrophobicContact CG-CG2 4.1Å; L230-V236 WeakPolarHBondContact O-CG2 3.41Å
231	A	88.1	Confident	91.2	Very high	38 Å²	38	58.8 Å²	58.8	31%	0.314	30%	0.302	S	S	.	.			trans	-90.2	-21.4	-169.9	0	0	0	0	0	113.4	K221 K224 L229 E233	K221-A231 PolarHBondContact O-N 3.29Å; K224-A231 HydrophobicContact CB-CB 4.28Å; L229-A231 HydrophobicContact CD1-CB 4.08Å; L229-A231 PolarHBondContact O-N 3.34Å; A231-E233 PolarHBondContact O-N 3.35Å
232	D	91	Very high	91.3	Very high	20 Å²	20	58.6 Å²	58.6	11%	0.107	31%	0.306	C	S	.	.			trans	-75.2	123.7	-178.6	-171.9	-89.5	0	0	0	112.3	K221 N234 F235 V236	K221-D232 HydrophobicContact CD-CB 3.75Å; K221-D232 VanDerWaalsContact CD-OD2 3.3Å; K221-D232 WeakPolarHBondContact CD-OD2 3.37Å; K221-D232 WeakPolarHBondContact CE-OD2 3.25Å; K221-D232 IonicContact NZ-OD2 3.7Å; K221-D232 PolarHBondContact NZ-OD2 3.25Å; D232-N234 VanDerWaalsContact C-N 3.32Å; D232-N234 PolarHBondContact O-N 3Å; D232-N234 WeakPolarHBondContact OD1-CA 3.41Å; D232-N234 VanDerWaalsContact OD1-CB 3.31Å; D232-N234 WeakPolarHBondContact OD1-CB 3.32Å; D232-N234 PolarHBondContact OD1-N 3.48Å; D232-F235 HydrophobicContact CB-CB 4.18Å; D232-F235 HydrophobicContact CB-CD2 3.5Å; D232-F235 HydrophobicContact CB-CE2 4.28Å; D232-F235 HydrophobicContact CB-CG 4.23Å; D232-F235 PolarHBondContact O-N 3.12Å; D232-F235 PolarHBondContact OD1-N 3.21Å; D232-V236 WeakPolarHBondContact O-CG2 3.41Å; D232-V236 PolarHBondContact O-N 2.89Å
233	E	91.1	Very high	91.2	Very high	79 Å²	79	58.9 Å²	58.9	37%	0.369	31%	0.309	S	S	.	.	H	α-helix	trans	-61.9	-37.7	-177.1	-61.3	178.7	-174.4	0	0	112.8	A231 V236 L237 V347 K350	A231-E233 PolarHBondContact O-N 3.35Å; E233-V236 PolarHBondContact O-N 3.44Å; E233-L237 WeakPolarHBondContact O-CB 3.39Å; E233-L237 VanDerWaalsContact O-CG 3.31Å; E233-L237 WeakPolarHBondContact O-CG 3.43Å; E233-L237 PolarHBondContact O-N 2.92Å; E233-V347 HydrophobicContact CB-CG1 3.7Å; E233-V347 HydrophobicContact CG-CG1 3.86Å; E233-K350 VanDerWaalsContact CD-CE 3.5Å; E233-K350 WeakPolarHBondContact OE1-CE 3.45Å; E233-K350 IonicContact OE1-NZ 2.68Å; E233-K350 PolarHBondContact OE1-NZ 3.23Å; E233-K350 VanDerWaalsContact OE2-CE 3.31Å; E233-K350 WeakPolarHBondContact OE2-CE 3.46Å; E233-K350 IonicContact OE2-NZ 3.62Å; E233-K350 PolarHBondContact OE2-NZ 2.94Å
234	N	91.6	Very high	91.2	Very high	105 Å²	105	57.1 Å²	57.1	56%	0.561	30%	0.301	S	S	*	.	H	α-helix	trans	-70.6	-41.8	-179.8	-61.4	-51.3	0	0	0	110.5	D232 L237 I238	D232-N234 VanDerWaalsContact C-N 3.32Å; D232-N234 PolarHBondContact O-N 3Å; D232-N234 WeakPolarHBondContact OD1-CA 3.41Å; D232-N234 VanDerWaalsContact OD1-CB 3.31Å; D232-N234 WeakPolarHBondContact OD1-CB 3.32Å; D232-N234 PolarHBondContact OD1-N 3.48Å; N234-L237 PolarHBondContact O-N 3.47Å; N234-I238 HydrophobicContact CB-CD1 4.42Å; N234-I238 VanDerWaalsContact O-CB 3.26Å; N234-I238 WeakPolarHBondContact O-CB 3.28Å; N234-I238 VanDerWaalsContact O-CG1 3.28Å; N234-I238 WeakPolarHBondContact O-CG1 3.34Å; N234-I238 PolarHBondContact O-N 3.22Å
235	F	90.7	Very high	91.5	Very high	44 Å²	44	55.3 Å²	55.3	19%	0.193	29%	0.293	C	S	.	.	H	α-helix	trans	-63.9	-41.4	174.6	-70.5	-49.4	0	0	0	112	P210 F214 L230 D232 G239	P210-F235 HydrophobicContact CB-CE1 4.09Å; F214-F235 HydrophobicContact CB-CE2 3.86Å; F214-F235 HydrophobicContact CB-CZ 3.73Å; F214-F235 HydrophobicContact CD1-CZ 4.46Å; F214-F235 AromaticContact CD2-CE1 3.81Å; F214-F235 HydrophobicContact CD2-CE1 3.81Å; F214-F235 HydrophobicContact CD2-CE2 4.26Å; F214-F235 AromaticContact CD2-CZ 3.28Å; F214-F235 HydrophobicContact CD2-CZ 3.28Å; F214-F235 HydrophobicContact CE2-CE1 4.26Å; F214-F235 AromaticContact CE2-CZ 3.98Å; F214-F235 HydrophobicContact CE2-CZ 3.98Å; F214-F235 HydrophobicContact CG-CE2 4.19Å; F214-F235 AromaticContact CG-CZ 3.57Å; F214-F235 HydrophobicContact CG-CZ 3.57Å; L230-F235 HydrophobicContact CD1-CB 4.04Å; L230-F235 HydrophobicContact CD1-CD2 4.49Å; L230-F235 HydrophobicContact CD2-CB 3.93Å; L230-F235 HydrophobicContact CG-CB 4.1Å; D232-F235 HydrophobicContact CB-CB 4.18Å; D232-F235 HydrophobicContact CB-CD2 3.5Å; D232-F235 HydrophobicContact CB-CE2 4.28Å; D232-F235 HydrophobicContact CB-CG 4.23Å; D232-F235 PolarHBondContact O-N 3.12Å; D232-F235 PolarHBondContact OD1-N 3.21Å; F235-G239 VanDerWaalsContact O-CA 3.24Å; F235-G239 WeakPolarHBondContact O-CA 3.33Å; F235-G239 PolarHBondContact O-N 3.47Å
236	V	92	Very high	91.9	Very high	6 Å²	6	51.8 Å²	51.8	4%	0.036	28%	0.281	C	S	.	.	H	α-helix	trans	-62.6	-47.7	176.8	171.4	0	0	0	0	111.2	L230 D232 E233 S240 N343 V347	L230-V236 HydrophobicContact CB-CG2 4.35Å; L230-V236 HydrophobicContact CD2-CG2 4.06Å; L230-V236 HydrophobicContact CG-CG2 4.1Å; L230-V236 WeakPolarHBondContact O-CG2 3.41Å; D232-V236 WeakPolarHBondContact O-CG2 3.41Å; D232-V236 PolarHBondContact O-N 2.89Å; E233-V236 PolarHBondContact O-N 3.44Å; V236-S240 WeakPolarHBondContact O-CB 3.36Å; V236-S240 PolarHBondContact O-N 3.14Å; V236-S240 PolarHBondContact O-OG 3.12Å; V236-N343 WeakPolarHBondContact CG1-ND2 3.5Å; V236-V347 HydrophobicContact CB-CG2 4.01Å; V236-V347 HydrophobicContact CG1-CG2 3.63Å
237	L	92.9	Very high	92.2	Very high	52 Å²	52	45.9 Å²	45.9	27%	0.272	25%	0.25	S	C	.	.	H	α-helix	trans	-67.5	-59.3	-179.4	-70.9	172.4	0	0	0	111.7	E233 N234 G239 S240 F241 V344 V347	E233-L237 WeakPolarHBondContact O-CB 3.39Å; E233-L237 VanDerWaalsContact O-CG 3.31Å; E233-L237 WeakPolarHBondContact O-CG 3.43Å; E233-L237 PolarHBondContact O-N 2.92Å; N234-L237 PolarHBondContact O-N 3.47Å; L237-G239 VanDerWaalsContact C-N 3.29Å; L237-G239 PolarHBondContact O-N 2.86Å; L237-S240 PolarHBondContact O-N 3.1Å; L237-S240 VanDerWaalsContact O-N 3.16Å; L237-F241 VanDerWaalsContact O-CD2 3.27Å; L237-F241 WeakPolarHBondContact O-CD2 3.15Å; L237-F241 PolarHBondContact O-N 3.27Å; L237-V344 HydrophobicContact CD2-CG1 4.12Å; L237-V347 HydrophobicContact CD1-CG1 3.96Å; L237-V347 HydrophobicContact CD2-CG1 4.33Å; L237-V347 HydrophobicContact CG-CG1 4.01Å
238	I	92.9	Very high	92.2	Very high	108 Å²	108	45.4 Å²	45.4	55%	0.554	24%	0.244	S	C	*	.	H	α-helix	trans	-60.6	-43.1	-177.3	-62.1	170.1	0	0	0	110	N234 S240 F241 V242	N234-I238 HydrophobicContact CB-CD1 4.42Å; N234-I238 VanDerWaalsContact O-CB 3.26Å; N234-I238 WeakPolarHBondContact O-CB 3.28Å; N234-I238 VanDerWaalsContact O-CG1 3.28Å; N234-I238 WeakPolarHBondContact O-CG1 3.34Å; N234-I238 PolarHBondContact O-N 3.22Å; I238-S240 PolarHBondContact O-N 3.45Å; I238-F241 PolarHBondContact O-N 2.92Å; I238-V242 HydrophobicContact CG2-CG2 4.18Å; I238-V242 WeakPolarHBondContact O-CB 3.27Å; I238-V242 WeakPolarHBondContact O-CG2 3.35Å; I238-V242 PolarHBondContact O-N 3.48Å
239	G	91.9	Very high	92.2	Very high	29 Å²	29	48.7 Å²	48.7	30%	0.299	26%	0.264	S	S	.	.	H	α-helix	trans	-58.6	-47.2	175.9	0	0	0	0	0	112.1	F235 L237 F241 V242 A243	F235-G239 VanDerWaalsContact O-CA 3.24Å; F235-G239 WeakPolarHBondContact O-CA 3.33Å; F235-G239 PolarHBondContact O-N 3.47Å; L237-G239 VanDerWaalsContact C-N 3.29Å; L237-G239 PolarHBondContact O-N 2.86Å; G239-F241 VanDerWaalsContact C-N 3.34Å; G239-F241 PolarHBondContact O-N 3.23Å; G239-V242 PolarHBondContact O-N 3.27Å; G239-A243 WeakPolarHBondContact O-CA 3.29Å; G239-A243 WeakPolarHBondContact O-CB 3.4Å; G239-A243 PolarHBondContact O-N 2.73Å
240	S	93.4	Very high	92.2	Very high	4 Å²	4	48.6 Å²	48.6	3%	0.028	26%	0.264	C	S	.	.	H	α-helix	trans	-61.1	-40.1	177.7	-62.2	0	0	0	0	112.5	V236 L237 I238 F244 F245	V236-S240 WeakPolarHBondContact O-CB 3.36Å; V236-S240 PolarHBondContact O-N 3.14Å; V236-S240 PolarHBondContact O-OG 3.12Å; L237-S240 PolarHBondContact O-N 3.1Å; L237-S240 VanDerWaalsContact O-N 3.16Å; I238-S240 PolarHBondContact O-N 3.45Å; S240-F244 WeakPolarHBondContact O-CA 3.2Å; S240-F244 VanDerWaalsContact O-CB 3.32Å; S240-F244 WeakPolarHBondContact O-CB 3.44Å; S240-F244 PolarHBondContact O-N 3.48Å; S240-F244 VanDerWaalsContact O-N 3.11Å; S240-F245 WeakPolarHBondContact O-CD2 3.35Å; S240-F245 PolarHBondContact O-N 3.47Å
241	F	93.1	Very high	92.2	Very high	110 Å²	110	46.8 Å²	46.8	48%	0.482	25%	0.254	S	S	.	.	I	π-helix	trans	-68.3	-49	177.4	-82.6	-81.4	0	0	0	112.8	L237 I238 G239 F245 I246	L237-F241 VanDerWaalsContact O-CD2 3.27Å; L237-F241 WeakPolarHBondContact O-CD2 3.15Å; L237-F241 PolarHBondContact O-N 3.27Å; I238-F241 PolarHBondContact O-N 2.92Å; G239-F241 VanDerWaalsContact C-N 3.34Å; G239-F241 PolarHBondContact O-N 3.23Å; F241-F245 HydrophobicContact CD1-CB 4.17Å; F241-F245 HydrophobicContact CD1-CD2 4.09Å; F241-F245 HydrophobicContact CE1-CD2 4.31Å; F241-F245 HydrophobicContact CG-CD2 4.25Å; F241-F245 PolarHBondContact O-N 3.47Å; F241-I246 WeakPolarHBondContact O-CB 3.5Å; F241-I246 WeakPolarHBondContact O-CG1 3.31Å; F241-I246 PolarHBondContact O-N 3.06Å
242	V	93	Very high	92.3	Very high	57 Å²	57	47.8 Å²	47.8	35%	0.345	26%	0.256	S	S	.	.	I	π-helix	trans	-74.6	-42.9	-174.2	176.5	0	0	0	0	111.8	I207 I238 G239 P247	I207-V242 HydrophobicContact CD1-CG1 3.89Å; I207-V242 HydrophobicContact CG1-CG1 3.78Å; I207-V242 HydrophobicContact CG2-CG1 3.96Å; I238-V242 HydrophobicContact CG2-CG2 4.18Å; I238-V242 WeakPolarHBondContact O-CB 3.27Å; I238-V242 WeakPolarHBondContact O-CG2 3.35Å; I238-V242 PolarHBondContact O-N 3.48Å; G239-V242 PolarHBondContact O-N 3.27Å; V242-P247 WeakPolarHBondContact O-CD 3.41Å
243	A	90.9	Very high	92.3	Very high	8 Å²	8	50.4 Å²	50.4	7%	0.066	27%	0.272	C	S	.	.	I	π-helix	trans	-83.5	-27.5	-176.3	0	0	0	0	0	113.2	T161 I164 I207 G239	T161-A243 HydrophobicContact CG2-CB 4.29Å; I164-A243 VanDerWaalsContact CG2-O 3.3Å; I164-A243 WeakPolarHBondContact CG2-O 3.38Å; I207-A243 HydrophobicContact CG2-CB 4.08Å; G239-A243 WeakPolarHBondContact O-CA 3.29Å; G239-A243 WeakPolarHBondContact O-CB 3.4Å; G239-A243 PolarHBondContact O-N 2.73Å
244	F	93.1	Very high	92.2	Very high	3 Å²	3	47 Å²	47	1%	0.013	26%	0.257	C	S	.	.	I	π-helix	trans	-121.8	-63.2	-174.2	-176.3	-104.6	0	0	0	114.2	I164 S240 I246 P247 L248 F332 W336 F340	I164-F244 HydrophobicContact CD1-CD2 3.79Å; I164-F244 HydrophobicContact CD1-CE2 4.32Å; S240-F244 WeakPolarHBondContact O-CA 3.2Å; S240-F244 VanDerWaalsContact O-CB 3.32Å; S240-F244 WeakPolarHBondContact O-CB 3.44Å; S240-F244 PolarHBondContact O-N 3.48Å; S240-F244 VanDerWaalsContact O-N 3.11Å; F244-I246 PolarHBondContact O-N 3.22Å; F244-P247 WeakPolarHBondContact O-CD 3.26Å; F244-L248 HydrophobicContact CD1-CD2 4.42Å; F244-L248 HydrophobicContact CE1-CD2 3.76Å; F244-L248 HydrophobicContact CZ-CD2 3.95Å; F244-L248 WeakPolarHBondContact O-CB 3.44Å; F244-L248 PolarHBondContact O-N 3.48Å; F244-F332 HydrophobicContact CD2-CE1 4.44Å; F244-F332 AromaticContact CE2-CE1 3.99Å; F244-F332 HydrophobicContact CE2-CE1 3.99Å; F244-W336 HydrophobicContact CE2-CB 3.58Å; F244-W336 HydrophobicContact CE2-CG 4.48Å; F244-W336 HydrophobicContact CZ-CB 4.03Å; F244-F340 HydrophobicContact CB-CD1 3.83Å; F244-F340 HydrophobicContact CB-CD2 4.05Å; F244-F340 HydrophobicContact CB-CE1 3.55Å; F244-F340 HydrophobicContact CB-CE2 3.79Å; F244-F340 HydrophobicContact CB-CG 4.08Å; F244-F340 HydrophobicContact CB-CZ 3.53Å; F244-F340 HydrophobicContact CD1-CB 3.79Å; F244-F340 HydrophobicContact CD1-CD1 4.01Å; F244-F340 AromaticContact CD1-CD2 3.53Å; F244-F340 HydrophobicContact CD1-CD2 3.53Å; F244-F340 HydrophobicContact CD1-CE2 4.11Å; F244-F340 AromaticContact CD1-CG 3.48Å; F244-F340 HydrophobicContact CD1-CG 3.48Å; F244-F340 VanDerWaalsContact CD1-CG 3.48Å; F244-F340 AromaticContact CD2-CD2 3.44Å; F244-F340 HydrophobicContact CD2-CD2 3.44Å; F244-F340 VanDerWaalsContact CD2-CD2 3.44Å; F244-F340 AromaticContact CD2-CE2 3.26Å; F244-F340 HydrophobicContact CD2-CE2 3.26Å; F244-F340 HydrophobicContact CD2-CG 4.2Å; F244-F340 AromaticContact CD2-CZ 3.91Å; F244-F340 HydrophobicContact CD2-CZ 3.91Å; F244-F340 HydrophobicContact CE1-CB 3.84Å; F244-F340 AromaticContact CE1-CD2 3.71Å; F244-F340 HydrophobicContact CE1-CD2 3.71Å; F244-F340 AromaticContact CE1-CG 3.88Å; F244-F340 HydrophobicContact CE1-CG 3.88Å; F244-F340 AromaticContact CE2-CD2 3.63Å; F244-F340 HydrophobicContact CE2-CD2 3.63Å; F244-F340 AromaticContact CE2-CE2 3.78Å; F244-F340 HydrophobicContact CE2-CE2 3.78Å; F244-F340 HydrophobicContact CG-CB 4.46Å; F244-F340 AromaticContact CG-CD1 3.96Å; F244-F340 HydrophobicContact CG-CD1 3.96Å; F244-F340 AromaticContact CG-CD2 3.39Å; F244-F340 HydrophobicContact CG-CD2 3.39Å; F244-F340 HydrophobicContact CG-CE1 4.01Å; F244-F340 AromaticContact CG-CE2 3.45Å; F244-F340 HydrophobicContact CG-CE2 3.45Å; F244-F340 VanDerWaalsContact CG-CE2 3.45Å; F244-F340 AromaticContact CG-CG 3.66Å; F244-F340 HydrophobicContact CG-CG 3.66Å; F244-F340 AromaticContact CG-CZ 3.78Å; F244-F340 HydrophobicContact CG-CZ 3.78Å; F244-F340 AromaticContact CZ-CD2 3.76Å; F244-F340 HydrophobicContact CZ-CD2 3.76Å; F244-F340 HydrophobicContact CZ-CE2 4.38Å; F244-F340 HydrophobicContact CZ-CG 4.39Å
245	F	94.2	Very high	92	Very high	52 Å²	52	45 Å²	45	23%	0.228	24%	0.242	C	C	.	.	I	π-helix	trans	-66.9	-38.4	-169.2	-66.9	-64.2	0	0	0	114.3	S240 F241 L248 T249 F340 V344	S240-F245 WeakPolarHBondContact O-CD2 3.35Å; S240-F245 PolarHBondContact O-N 3.47Å; F241-F245 HydrophobicContact CD1-CB 4.17Å; F241-F245 HydrophobicContact CD1-CD2 4.09Å; F241-F245 HydrophobicContact CE1-CD2 4.31Å; F241-F245 HydrophobicContact CG-CD2 4.25Å; F241-F245 PolarHBondContact O-N 3.47Å; F245-L248 HydrophobicContact CD1-CD2 4.48Å; F245-T249 WeakPolarHBondContact O-CB 3.41Å; F245-T249 PolarHBondContact O-N 2.67Å; F245-T249 PolarHBondContact O-OG1 2.89Å; F245-F340 HydrophobicContact CZ-CB 4.22Å; F245-V344 HydrophobicContact CE2-CG2 4.08Å
246	I	94.2	Very high	91.9	Very high	89 Å²	89	49.3 Å²	49.3	46%	0.456	26%	0.261	S	S	.	.	H	α-helix	trans	-66.2	-54.7	177.1	-69.9	169.3	0	0	0	110.6	F241 F244 L248 T249 I250	F241-I246 WeakPolarHBondContact O-CB 3.5Å; F241-I246 WeakPolarHBondContact O-CG1 3.31Å; F241-I246 PolarHBondContact O-N 3.06Å; F244-I246 PolarHBondContact O-N 3.22Å; I246-L248 VanDerWaalsContact C-N 3.28Å; I246-L248 PolarHBondContact O-N 3.29Å; I246-T249 PolarHBondContact O-N 3.39Å; I246-I250 HydrophobicContact CG2-CD1 4.06Å; I246-I250 WeakPolarHBondContact O-CG1 3.39Å; I246-I250 PolarHBondContact O-N 3.32Å; I246-I250 VanDerWaalsContact O-N 3.07Å
247	P	92.9	Very high	91.8	Very high	3 Å²	3	52.4 Å²	52.4	2%	0.019	28%	0.277	C	S	.	.	H	α-helix	trans	-58.7	-38.4	175.9	-25.2	33.9	0	0	0	113.2	I164 M165 V242 F244 I250 M251	I164-P247 HydrophobicContact CD1-CB 3.85Å; I164-P247 HydrophobicContact CG1-CB 3.96Å; I164-P247 HydrophobicContact CG2-CB 4.49Å; M165-P247 HydrophobicContact SD-CB 4Å; M165-P247 HydrophobicContact SD-CG 3.65Å; V242-P247 WeakPolarHBondContact O-CD 3.41Å; F244-P247 WeakPolarHBondContact O-CD 3.26Å; P247-I250 PolarHBondContact O-N 2.94Å; P247-M251 WeakPolarHBondContact O-CB 3.31Å; P247-M251 PolarHBondContact O-N 3.02Å
248	L	92.5	Very high	91.5	Very high	21 Å²	21	50.2 Å²	50.2	11%	0.11	27%	0.266	C	S	.	.	H	α-helix	trans	-58.6	-48.6	175.1	174.7	62.6	0	0	0	111.6	F244 F245 I246 I250 M251 V252 V333	F244-L248 HydrophobicContact CD1-CD2 4.42Å; F244-L248 HydrophobicContact CE1-CD2 3.76Å; F244-L248 HydrophobicContact CZ-CD2 3.95Å; F244-L248 WeakPolarHBondContact O-CB 3.44Å; F244-L248 PolarHBondContact O-N 3.48Å; F245-L248 HydrophobicContact CD1-CD2 4.48Å; I246-L248 VanDerWaalsContact C-N 3.28Å; I246-L248 PolarHBondContact O-N 3.29Å; L248-I250 VanDerWaalsContact C-N 3.33Å; L248-I250 PolarHBondContact O-N 3.13Å; L248-M251 HydrophobicContact CD1-CE 3.82Å; L248-M251 PolarHBondContact O-N 3.49Å; L248-V252 HydrophobicContact CD1-CG2 4.09Å; L248-V252 VanDerWaalsContact O-CG2 3.32Å; L248-V252 WeakPolarHBondContact O-CG2 3.35Å; L248-V252 PolarHBondContact O-N 2.97Å; L248-V333 HydrophobicContact CD1-CB 4.32Å; L248-V333 HydrophobicContact CD1-CG1 4.16Å; L248-V333 HydrophobicContact CD1-CG2 3.3Å
249	T	92.9	Very high	91.2	Very high	85 Å²	85	47.5 Å²	47.5	52%	0.521	25%	0.252	S	S	.	.	H	α-helix	trans	-60.7	-44.5	179.3	-57.9	0	0	0	0	110.9	F245 I246 M251 V252 V253	F245-T249 WeakPolarHBondContact O-CB 3.41Å; F245-T249 PolarHBondContact O-N 2.67Å; F245-T249 PolarHBondContact O-OG1 2.89Å; I246-T249 PolarHBondContact O-N 3.39Å; T249-M251 PolarHBondContact O-N 2.99Å; T249-V252 PolarHBondContact O-N 2.72Å; T249-V253 HydrophobicContact CG2-CG2 4.37Å; T249-V253 WeakPolarHBondContact O-CB 3.48Å; T249-V253 VanDerWaalsContact O-CG2 3.29Å; T249-V253 WeakPolarHBondContact O-CG2 3.41Å; T249-V253 PolarHBondContact O-N 3.42Å
250	I	92.3	Very high	90.9	Very high	67 Å²	67	53.2 Å²	53.2	34%	0.344	27%	0.269	S	S	.	.	H	α-helix	trans	-60.7	-47	176.4	-62.9	167.1	0	0	0	110.4	C168 L172 I246 P247 L248 V252 V253 T254	C168-I250 WeakPolarHBondContact SG-CG2 3.42Å; L172-I250 HydrophobicContact CD1-CG2 3.99Å; L172-I250 HydrophobicContact CD2-CG2 4.33Å; L172-I250 HydrophobicContact CG-CG2 4.19Å; I246-I250 HydrophobicContact CG2-CD1 4.06Å; I246-I250 WeakPolarHBondContact O-CG1 3.39Å; I246-I250 PolarHBondContact O-N 3.32Å; I246-I250 VanDerWaalsContact O-N 3.07Å; P247-I250 PolarHBondContact O-N 2.94Å; L248-I250 VanDerWaalsContact C-N 3.33Å; L248-I250 PolarHBondContact O-N 3.13Å; I250-V252 PolarHBondContact O-N 2.89Å; I250-V253 PolarHBondContact O-N 2.94Å; I250-T254 HydrophobicContact CG2-CG2 4.04Å; I250-T254 VanDerWaalsContact O-CB 3.28Å; I250-T254 WeakPolarHBondContact O-CB 3.34Å; I250-T254 WeakPolarHBondContact O-CG2 3.47Å; I250-T254 PolarHBondContact O-N 3.5Å; I250-T254 PolarHBondContact O-OG1 3.44Å
251	M	90.7	Very high	90.5	Very high	2 Å²	2	54.2 Å²	54.2	1%	0.01	28%	0.276	C	S	.	.	H	α-helix	trans	-59.5	-46.7	179.1	-175.3	-179.7	63.5	0	0	111.6	L167 P247 L248 T249 T254 Y255 F329 V333	L167-M251 HydrophobicContact CB-SD 4.04Å; P247-M251 WeakPolarHBondContact O-CB 3.31Å; P247-M251 PolarHBondContact O-N 3.02Å; L248-M251 HydrophobicContact CD1-CE 3.82Å; L248-M251 PolarHBondContact O-N 3.49Å; T249-M251 PolarHBondContact O-N 2.99Å; M251-T254 WeakPolarHBondContact CA-OG1 3.48Å; M251-T254 PolarHBondContact O-OG1 3.44Å; M251-Y255 VanDerWaalsContact O-CB 3.22Å; M251-Y255 WeakPolarHBondContact O-CB 3.4Å; M251-Y255 PolarHBondContact O-N 3.39Å; M251-F329 HydrophobicContact CE-CB 4.08Å; M251-F329 HydrophobicContact CG-CB 4.33Å; M251-F329 HydrophobicContact CG-CD1 4.32Å; M251-F329 HydrophobicContact CG-CD2 4.1Å; M251-F329 HydrophobicContact CG-CG 4Å; M251-F329 HydrophobicContact SD-CB 3.7Å; M251-F329 HydrophobicContact SD-CD1 3.59Å; M251-F329 VanDerWaalsContact SD-CD1 3.59Å; M251-F329 HydrophobicContact SD-CD2 4.31Å; M251-F329 HydrophobicContact SD-CE1 4.29Å; M251-F329 HydrophobicContact SD-CG 3.61Å; M251-V333 HydrophobicContact CE-CG2 3.71Å
252	V	90.6	Very high	89.9	Confident	59 Å²	59	49.3 Å²	49.3	36%	0.358	26%	0.255	S	S	.	.	H	α-helix	trans	-63.2	-50.7	179.3	171.8	0	0	0	0	111.1	L248 T249 I250 T254 Y255 F256	L248-V252 HydrophobicContact CD1-CG2 4.09Å; L248-V252 VanDerWaalsContact O-CG2 3.32Å; L248-V252 WeakPolarHBondContact O-CG2 3.35Å; L248-V252 PolarHBondContact O-N 2.97Å; T249-V252 PolarHBondContact O-N 2.72Å; I250-V252 PolarHBondContact O-N 2.89Å; V252-T254 PolarHBondContact O-N 2.96Å; V252-Y255 PolarHBondContact O-N 2.87Å; V252-F256 HydrophobicContact CG1-CD2 3.72Å; V252-F256 HydrophobicContact CG1-CE2 3.47Å; V252-F256 VanDerWaalsContact CG1-CE2 3.47Å; V252-F256 WeakPolarHBondContact O-CD2 3.42Å; V252-F256 PolarHBondContact O-N 3.38Å
253	V	91.9	Very high	89.4	Confident	75 Å²	75	52.2 Å²	52.2	46%	0.455	26%	0.264	S	S	.	.	H	α-helix	trans	-60.6	-48.3	179.7	171.1	0	0	0	0	110.9	T249 I250 Y255 F256 L257	T249-V253 HydrophobicContact CG2-CG2 4.37Å; T249-V253 WeakPolarHBondContact O-CB 3.48Å; T249-V253 VanDerWaalsContact O-CG2 3.29Å; T249-V253 WeakPolarHBondContact O-CG2 3.41Å; T249-V253 PolarHBondContact O-N 3.42Å; I250-V253 PolarHBondContact O-N 2.94Å; V253-Y255 VanDerWaalsContact C-N 3.3Å; V253-Y255 PolarHBondContact O-N 3.27Å; V253-F256 PolarHBondContact O-N 2.94Å; V253-L257 HydrophobicContact CG1-CD1 3.95Å; V253-L257 HydrophobicContact CG1-CG 4.37Å; V253-L257 VanDerWaalsContact O-CG 3.27Å; V253-L257 WeakPolarHBondContact O-CG 3.49Å; V253-L257 PolarHBondContact O-N 3.23Å
254	T	89.5	Confident	89.1	Confident	9 Å²	9	58.8 Å²	58.8	6%	0.055	29%	0.291	C	S	.	.	H	α-helix	trans	-65	-34.3	-179.2	53.8	0	0	0	0	112.4	S171 L172 I250 M251 V252 L257 T258	S171-T254 WeakPolarHBondContact CB-OG1 3.27Å; S171-T254 PolarHBondContact OG-OG1 3.28Å; L172-T254 HydrophobicContact CD2-CG2 3.41Å; L172-T254 VanDerWaalsContact CD2-CG2 3.41Å; L172-T254 HydrophobicContact CG-CG2 3.96Å; I250-T254 HydrophobicContact CG2-CG2 4.04Å; I250-T254 VanDerWaalsContact O-CB 3.28Å; I250-T254 WeakPolarHBondContact O-CB 3.34Å; I250-T254 WeakPolarHBondContact O-CG2 3.47Å; I250-T254 PolarHBondContact O-N 3.5Å; I250-T254 PolarHBondContact O-OG1 3.44Å; M251-T254 WeakPolarHBondContact CA-OG1 3.48Å; M251-T254 PolarHBondContact O-OG1 3.44Å; V252-T254 PolarHBondContact O-N 2.96Å; T254-L257 PolarHBondContact O-N 3.47Å; T254-T258 WeakPolarHBondContact O-CB 3.34Å; T254-T258 PolarHBondContact O-N 3.47Å; T254-T258 PolarHBondContact O-OG1 3.35Å
255	Y	86.9	Confident	88.3	Confident	62 Å²	62	61.3 Å²	61.3	24%	0.243	30%	0.303	C	S	.	.	H	α-helix	trans	-65.6	-46.7	174	179.1	-109.9	0	0	0	112.3	M251 V252 V253 L257 T258 I259 F329	M251-Y255 VanDerWaalsContact O-CB 3.22Å; M251-Y255 WeakPolarHBondContact O-CB 3.4Å; M251-Y255 PolarHBondContact O-N 3.39Å; V252-Y255 PolarHBondContact O-N 2.87Å; V253-Y255 VanDerWaalsContact C-N 3.3Å; V253-Y255 PolarHBondContact O-N 3.27Å; Y255-L257 VanDerWaalsContact C-N 3.33Å; Y255-L257 PolarHBondContact O-N 3.38Å; Y255-T258 WeakPolarHBondContact O-CB 3.47Å; Y255-T258 PolarHBondContact O-N 3.48Å; Y255-T258 VanDerWaalsContact O-N 3.13Å; Y255-I259 HydrophobicContact CD1-CD1 3.83Å; Y255-I259 HydrophobicContact CE1-CD1 3.26Å; Y255-I259 HydrophobicContact CE1-CG1 4.31Å; Y255-I259 HydrophobicContact CE2-CD1 4.02Å; Y255-I259 HydrophobicContact CE2-CG1 4.27Å; Y255-I259 HydrophobicContact CG-CD1 4.45Å; Y255-I259 PolarHBondContact O-N 3.46Å; Y255-F329 HydrophobicContact CD2-CD2 4.09Å; Y255-F329 HydrophobicContact CD2-CE2 4.39Å
256	F	88.6	Confident	87.5	Confident	135 Å²	135	59.9 Å²	59.9	59%	0.592	30%	0.301	S	S	*	.	H	α-helix	trans	-60.7	-43	175.2	-79.5	-64.6	0	0	0	112.2	V252 V253 T258 I259 K260	V252-F256 HydrophobicContact CG1-CD2 3.72Å; V252-F256 HydrophobicContact CG1-CE2 3.47Å; V252-F256 VanDerWaalsContact CG1-CE2 3.47Å; V252-F256 WeakPolarHBondContact O-CD2 3.42Å; V252-F256 PolarHBondContact O-N 3.38Å; V253-F256 PolarHBondContact O-N 2.94Å; F256-T258 VanDerWaalsContact C-N 3.28Å; F256-T258 PolarHBondContact O-N 2.99Å; F256-I259 PolarHBondContact O-N 3.07Å; F256-K260 WeakPolarHBondContact O-CB 3.49Å; F256-K260 PolarHBondContact O-N 2.93Å
257	L	89.6	Confident	86.8	Confident	71 Å²	71	59.3 Å²	59.3	37%	0.372	30%	0.302	S	S	.	.	H	α-helix	trans	-62.3	-37.4	175.2	-67.9	176.4	0	0	0	111.9	Y175 V253 T254 Y255 K260 S261	Y175-L257 HydrophobicContact CD2-CB 3.85Å; Y175-L257 HydrophobicContact CE2-CB 3.55Å; Y175-L257 HydrophobicContact CE2-CD1 4.43Å; V253-L257 HydrophobicContact CG1-CD1 3.95Å; V253-L257 HydrophobicContact CG1-CG 4.37Å; V253-L257 VanDerWaalsContact O-CG 3.27Å; V253-L257 WeakPolarHBondContact O-CG 3.49Å; V253-L257 PolarHBondContact O-N 3.23Å; T254-L257 PolarHBondContact O-N 3.47Å; Y255-L257 VanDerWaalsContact C-N 3.33Å; Y255-L257 PolarHBondContact O-N 3.38Å; L257-K260 PolarHBondContact O-N 3.02Å; L257-S261 WeakPolarHBondContact O-CB 3.25Å; L257-S261 PolarHBondContact O-N 2.92Å
258	T	86.3	Confident	86	Confident	6 Å²	6	64.2 Å²	64.2	4%	0.037	33%	0.327	C	S	.	.	H	α-helix	trans	-63.6	-49.5	176	-63.2	0	0	0	0	111.5	Y175 I178 T254 Y255 F256 K260 S261 L262	Y175-T258 WeakPolarHBondContact CB-OG1 3.3Å; I178-T258 HydrophobicContact CD1-CG2 3.56Å; T254-T258 WeakPolarHBondContact O-CB 3.34Å; T254-T258 PolarHBondContact O-N 3.47Å; T254-T258 PolarHBondContact O-OG1 3.35Å; Y255-T258 WeakPolarHBondContact O-CB 3.47Å; Y255-T258 PolarHBondContact O-N 3.48Å; Y255-T258 VanDerWaalsContact O-N 3.13Å; F256-T258 VanDerWaalsContact C-N 3.28Å; F256-T258 PolarHBondContact O-N 2.99Å; T258-K260 VanDerWaalsContact C-N 3.35Å; T258-K260 PolarHBondContact O-N 2.97Å; T258-S261 PolarHBondContact O-N 2.84Å; T258-L262 HydrophobicContact CG2-CD1 3.98Å; T258-L262 WeakPolarHBondContact O-CG 3.19Å; T258-L262 PolarHBondContact O-N 3.49Å
259	I	85.6	Confident	84.8	Confident	51 Å²	51	65.5 Å²	65.5	26%	0.262	34%	0.337	S	S	.	.	H	α-helix	trans	-59.3	-47.2	176.9	-68	165.9	0	0	0	110.7	Y255 F256 S261 L262 Q263	Y255-I259 HydrophobicContact CD1-CD1 3.83Å; Y255-I259 HydrophobicContact CE1-CD1 3.26Å; Y255-I259 HydrophobicContact CE1-CG1 4.31Å; Y255-I259 HydrophobicContact CE2-CD1 4.02Å; Y255-I259 HydrophobicContact CE2-CG1 4.27Å; Y255-I259 HydrophobicContact CG-CD1 4.45Å; Y255-I259 PolarHBondContact O-N 3.46Å; F256-I259 PolarHBondContact O-N 3.07Å; I259-S261 VanDerWaalsContact C-N 3.3Å; I259-S261 PolarHBondContact O-N 3.34Å; I259-L262 PolarHBondContact O-N 3.26Å; I259-Q263 HydrophobicContact CG2-CG 4.23Å; I259-Q263 WeakPolarHBondContact O-CB 3.3Å; I259-Q263 WeakPolarHBondContact O-CG 3.34Å; I259-Q263 PolarHBondContact O-N 3.03Å
260	K	86.9	Confident	83.7	Confident	148 Å²	148	66.2 Å²	66.2	64%	0.643	34%	0.341	S	S	*	.	H	α-helix	trans	-60.8	-40.5	179.8	-174.3	178.4	179.4	177.5	0	111.7	F256 L257 T258 Q263 K264	F256-K260 WeakPolarHBondContact O-CB 3.49Å; F256-K260 PolarHBondContact O-N 2.93Å; L257-K260 PolarHBondContact O-N 3.02Å; T258-K260 VanDerWaalsContact C-N 3.35Å; T258-K260 PolarHBondContact O-N 2.97Å; K260-Q263 PolarHBondContact O-N 3.45Å; K260-K264 WeakPolarHBondContact O-CB 3.48Å; K260-K264 PolarHBondContact O-N 2.83Å
261	S	84.1	Confident	82.2	Confident	25 Å²	25	68.2 Å²	68.2	18%	0.175	35%	0.353	C	S	.	.	H	α-helix	trans	-64	-45.7	176.3	-159.6	0	0	0	0	111.5	L257 T258 I259 Q263 K264 E265	L257-S261 WeakPolarHBondContact O-CB 3.25Å; L257-S261 PolarHBondContact O-N 2.92Å; T258-S261 PolarHBondContact O-N 2.84Å; I259-S261 VanDerWaalsContact C-N 3.3Å; I259-S261 PolarHBondContact O-N 3.34Å; S261-Q263 VanDerWaalsContact C-N 3.35Å; S261-Q263 PolarHBondContact O-N 3.05Å; S261-K264 PolarHBondContact O-N 2.92Å; S261-E265 PolarHBondContact O-N 2.76Å
262	L	80.3	Confident	80.3	Confident	8 Å²	8	73.6 Å²	73.6	4%	0.042	38%	0.382	C	S	.	.	H	α-helix	trans	-64.7	-36.5	177.8	-72.1	168.7	0	0	0	112.9	I178 T258 I259 A266 E318 Q319 S322	I178-L262 HydrophobicContact CD1-CD1 4.02Å; I178-L262 HydrophobicContact CD1-CD2 3.78Å; I178-L262 HydrophobicContact CD1-CG 3.88Å; I178-L262 HydrophobicContact CG1-CD2 4.13Å; I178-L262 HydrophobicContact CG2-CD2 4.08Å; I178-L262 HydrophobicContact CG2-CG 4.34Å; T258-L262 HydrophobicContact CG2-CD1 3.98Å; T258-L262 WeakPolarHBondContact O-CG 3.19Å; T258-L262 PolarHBondContact O-N 3.49Å; I259-L262 PolarHBondContact O-N 3.26Å; L262-A266 WeakPolarHBondContact O-CB 3.34Å; L262-A266 PolarHBondContact O-N 2.92Å; L262-E318 HydrophobicContact CD2-CB 4.47Å; L262-Q319 HydrophobicContact CB-CG 4.39Å; L262-Q319 HydrophobicContact CD2-CG 4.47Å; L262-S322 WeakPolarHBondContact CD1-OG 3.26Å
263	Q	83.4	Confident	78.1	Confident	118 Å²	118	75 Å²	75	55%	0.551	39%	0.392	S	S	*	.	H	α-helix	trans	-65.1	-44.9	174	-75.4	175.7	-17.1	0	0	110.8	I259 K260 S261 E265 A266 T267	I259-Q263 HydrophobicContact CG2-CG 4.23Å; I259-Q263 WeakPolarHBondContact O-CB 3.3Å; I259-Q263 WeakPolarHBondContact O-CG 3.34Å; I259-Q263 PolarHBondContact O-N 3.03Å; K260-Q263 PolarHBondContact O-N 3.45Å; S261-Q263 VanDerWaalsContact C-N 3.35Å; S261-Q263 PolarHBondContact O-N 3.05Å; Q263-E265 PolarHBondContact O-N 2.84Å; Q263-A266 PolarHBondContact O-N 3.21Å; Q263-T267 PolarHBondContact O-N 3.13Å; Q263-T267 PolarHBondContact O-OG1 3.38Å; Q263-T267 VanDerWaalsContact O-OG1 3.07Å
264	K	83.5	Confident	76	Confident	145 Å²	145	73.6 Å²	73.6	63%	0.63	39%	0.393	S	S	*	.	H	α-helix	trans	-60.1	-45.1	177.8	-173.5	179.9	179.3	-177.1	0	111.9	K260 S261 T267 L268	K260-K264 WeakPolarHBondContact O-CB 3.48Å; K260-K264 PolarHBondContact O-N 2.83Å; S261-K264 PolarHBondContact O-N 2.92Å; K264-T267 PolarHBondContact O-N 2.76Å; K264-L268 HydrophobicContact CG-CD1 4.3Å; K264-L268 WeakPolarHBondContact O-CG 3.47Å; K264-L268 PolarHBondContact O-N 2.95Å
265	E	78.1	Confident	73.7	Confident	56 Å²	56	78.9 Å²	78.9	26%	0.262	43%	0.427	S	S	.	.	H	α-helix	trans	-64.3	-41.3	176.8	-73.1	-173.6	175	0	0	112.5	S261 Q263 T267 L268 C269	S261-E265 PolarHBondContact O-N 2.76Å; Q263-E265 PolarHBondContact O-N 2.84Å; E265-T267 PolarHBondContact O-N 3.42Å; E265-L268 PolarHBondContact O-N 3.31Å; E265-C269 PolarHBondContact O-N 3.1Å; E265-C269 PolarHBondContact O-SG 3.42Å
266	A	77.1	Confident	71.4	Confident	22 Å²	22	84.3 Å²	84.3	18%	0.182	45%	0.452	C	S	.	.	H	α-helix	trans	-62.5	-42.1	175.7	0	0	0	0	0	112	L262 Q263 C269 V270	L262-A266 WeakPolarHBondContact O-CB 3.34Å; L262-A266 PolarHBondContact O-N 2.92Å; Q263-A266 PolarHBondContact O-N 3.21Å; A266-C269 PolarHBondContact O-N 3.16Å; A266-V270 WeakPolarHBondContact O-CG2 3.29Å; A266-V270 PolarHBondContact O-N 3.4Å; A266-V270 VanDerWaalsContact O-N 3.09Å
267	T	78.7	Confident	69.1	Low	77 Å²	77	83.5 Å²	83.5	47%	0.472	46%	0.459	S	S	.	.	H	α-helix	trans	-65.5	-40.5	176.1	-57.5	0	0	0	0	112	Q263 K264 E265 C269 V270 N271	Q263-T267 PolarHBondContact O-N 3.13Å; Q263-T267 PolarHBondContact O-OG1 3.38Å; Q263-T267 VanDerWaalsContact O-OG1 3.07Å; K264-T267 PolarHBondContact O-N 2.76Å; E265-T267 PolarHBondContact O-N 3.42Å; T267-C269 PolarHBondContact O-N 3Å; T267-V270 PolarHBondContact O-N 3.22Å; T267-N271 VanDerWaalsContact CG2-ND2 3.35Å; T267-N271 WeakPolarHBondContact CG2-ND2 3.3Å; T267-N271 VanDerWaalsContact O-CB 3.24Å; T267-N271 WeakPolarHBondContact O-CB 3.17Å; T267-N271 VanDerWaalsContact O-CG 3.24Å; T267-N271 PolarHBondContact O-N 2.83Å; T267-N271 PolarHBondContact O-ND2 2.81Å
268	L	76.3	Confident	66.5	Low	107 Å²	107	89.9 Å²	89.9	56%	0.56	48%	0.483	S	S	*	.	H	α-helix	trans	-63.2	-40.2	175.8	-73.3	171.3	0	0	0	112	K264 E265 V270 N271 D272	K264-L268 HydrophobicContact CG-CD1 4.3Å; K264-L268 WeakPolarHBondContact O-CG 3.47Å; K264-L268 PolarHBondContact O-N 2.95Å; E265-L268 PolarHBondContact O-N 3.31Å; L268-V270 VanDerWaalsContact C-N 3.35Å; L268-V270 PolarHBondContact O-N 2.99Å; L268-N271 PolarHBondContact O-N 3.27Å; L268-D272 PolarHBondContact O-N 3.06Å
269	C	67.3	Low	64.1	Low	47 Å²	47	98.1 Å²	98.1	32%	0.318	52%	0.519	S	S	.	.	H	α-helix	trans	-70.5	-27.4	176.7	-70.5	0	0	0	0	114.2	E265 A266 T267 I315	E265-C269 PolarHBondContact O-N 3.1Å; E265-C269 PolarHBondContact O-SG 3.42Å; A266-C269 PolarHBondContact O-N 3.16Å; T267-C269 PolarHBondContact O-N 3Å; C269-I315 HydrophobicContact CB-CD1 4.26Å; C269-I315 WeakPolarHBondContact SG-CD1 3.08Å
270	V	69.9	Low	61.6	Low	100 Å²	100	99.3 Å²	99.3	61%	0.606	54%	0.536	S	S	*	.	H	α-helix	trans	-79.9	-35	174.1	172.3	0	0	0	0	111.2	A266 T267 L268 M312	A266-V270 WeakPolarHBondContact O-CG2 3.29Å; A266-V270 PolarHBondContact O-N 3.4Å; A266-V270 VanDerWaalsContact O-N 3.09Å; T267-V270 PolarHBondContact O-N 3.22Å; L268-V270 VanDerWaalsContact C-N 3.35Å; L268-V270 PolarHBondContact O-N 2.99Å; V270-M312 HydrophobicContact CG2-CE 4.07Å
271	N	61.7	Low	59.4	Low	110 Å²	110	98.1 Å²	98.1	59%	0.588	55%	0.546	S	S	*	.	H	α-helix	trans	-84.6	-10.6	-178.5	-71.3	-12.3	0	0	0	113.9	T267 L268 P273	T267-N271 VanDerWaalsContact CG2-ND2 3.35Å; T267-N271 WeakPolarHBondContact CG2-ND2 3.3Å; T267-N271 VanDerWaalsContact O-CB 3.24Å; T267-N271 WeakPolarHBondContact O-CB 3.17Å; T267-N271 VanDerWaalsContact O-CG 3.24Å; T267-N271 PolarHBondContact O-N 2.83Å; T267-N271 PolarHBondContact O-ND2 2.81Å; L268-N271 PolarHBondContact O-N 3.27Å; N271-P273 WeakPolarHBondContact O-CD 3.38Å
272	D	49.7	Very low	57	Low	115 Å²	115	106.3 Å²	106.3	62%	0.615	58%	0.579	S	S	*	*			trans	-72.4	98.2	169.8	-169.8	11	0	0	0	108.8	L268 G274	L268-D272 PolarHBondContact O-N 3.06Å; D272-G274 VanDerWaalsContact C-N 3.28Å; D272-G274 PolarHBondContact O-N 3.37Å
273	P	44.9	Very low	55.1	Low	88 Å²	88	110.1 Å²	110.1	57%	0.571	61%	0.607	S	S	*	*			trans	-77.6	94.1	173.1	15.2	6.8	0	0	0	103.7	N271	N271-P273 WeakPolarHBondContact O-CD 3.38Å
274	G	47.2	Very low	52.9	Low	46 Å²	46	113.6 Å²	113.6	47%	0.474	62%	0.62	S	S	.	*	T	Hydrogen-bonded Turn	trans	-39.2	141.8	177.9	0	0	0	0	0	110.5	D272 K276	D272-G274 VanDerWaalsContact C-N 3.28Å; D272-G274 PolarHBondContact O-N 3.37Å; G274-K276 PolarHBondContact O-N 3.28Å
275	P	41.6	Very low	50.4	Low	120 Å²	120	114.8 Å²	114.8	78%	0.779	63%	0.633	S	S	*	*	T	Hydrogen-bonded Turn	trans	-48.4	98.9	-152.6	19	-32.2	0	0	0	110.6	T277	P275-T277 VanDerWaalsContact C-N 3.26Å; P275-T277 PolarHBondContact O-N 3.16Å
276	K	39.1	Very low	48.5	Very low	175 Å²	175	117.9 Å²	117.9	76%	0.761	66%	0.658	S	S	*	*			trans	-68.3	100.7	164.8	-74.2	-173	-179.9	178.7	0	103.8	G274 K278	G274-K276 PolarHBondContact O-N 3.28Å; K276-K278 PolarHBondContact O-N 3.32Å
277	T	38.8	Very low	46.9	Very low	119 Å²	119	126.4 Å²	126.4	73%	0.73	69%	0.694	S	S	*	*			trans	-46.8	95.2	163.2	17.9	0	0	0	0	107.5	P275 F279	P275-T277 VanDerWaalsContact C-N 3.26Å; P275-T277 PolarHBondContact O-N 3.16Å; T277-F279 HydrophobicContact CG2-CD2 4.44Å; T277-F279 PolarHBondContact O-N 2.87Å
278	K	36.3	Very low	44.8	Very low	205 Å²	205	127.9 Å²	127.9	89%	0.891	71%	0.707	S	S	*	*			trans	-69.3	79.8	155.8	-74.8	-172.6	178.9	-179.5	0	105.1	K276 A280	K276-K278 PolarHBondContact O-N 3.32Å; K278-A280 PolarHBondContact O-N 3.02Å
279	F	34.7	Very low	42.8	Very low	179 Å²	179	128 Å²	128	79%	0.785	72%	0.717	S	S	*	*			trans	-64.7	101	151.4	-106.2	-88.8	0	0	0	104.6	T277 S281	T277-F279 HydrophobicContact CG2-CD2 4.44Å; T277-F279 PolarHBondContact O-N 2.87Å; F279-S281 PolarHBondContact O-N 2.86Å; F279-S281 VanDerWaalsContact O-N 3.16Å
280	A	34.5	Very low	41.5	Very low	76 Å²	76	133.4 Å²	133.4	63%	0.628	74%	0.742	S	S	*	*			trans	-50.6	120.9	166.7	0	0	0	0	0	107.2	K278 F282	K278-A280 PolarHBondContact O-N 3.02Å; A280-F282 PolarHBondContact O-N 3.46Å
281	S	40.1	Very low	40.3	Very low	122 Å²	122	134.2 Å²	134.2	85%	0.853	75%	0.752	S	S	*	*			trans	-63.1	90.7	160.5	-75.3	0	0	0	0	107.4	F279	F279-S281 PolarHBondContact O-N 2.86Å; F279-S281 VanDerWaalsContact O-N 3.16Å
282	F	33.4	Very low	39.4	Very low	197 Å²	197	133.4 Å²	133.4	86%	0.864	76%	0.755	S	S	*	*			trans	-123.9	117.7	149.4	-98.1	-86.8	0	0	0	107	A280	A280-F282 PolarHBondContact O-N 3.46Å
283	S	39.9	Very low	39.1	Very low	88 Å²	88	135.3 Å²	135.3	62%	0.615	76%	0.76	S	S	*	*			trans	-68.9	170.3	-175.6	40.9	0	0	0	0	113.1
284	F	37.8	Very low	39.1	Very low	191 Å²	191	140 Å²	140	84%	0.838	77%	0.771	S	S	*	*			trans	95.2	96.2	165.9	-57.6	-77.6	0	0	0	115.7
285	L	32.3	Very low	39	Very low	171 Å²	171	144.1 Å²	144.1	90%	0.895	78%	0.782	S	S	*	*				-173.3	143.8	126.6	-92.5	166.4	0	0	0	110
286	P	37	Very low	39	Very low	121 Å²	121	145.1 Å²	145.1	79%	0.786	77%	0.774	S	S	*	*			trans	-79.9	147.2	-174.4	31.3	-30.6	0	0	0	112.7
287	Q	43.9	Very low	39.1	Very low	200 Å²	200	141.9 Å²	141.9	94%	0.935	76%	0.762	S	S	*	*			trans	-70.9	125.7	-172	-171.2	165.2	-10.7	0	0	112.8
288	S	33.6	Very low	39.3	Very low	108 Å²	108	145.8 Å²	145.8	76%	0.755	76%	0.763	S	S	*	*			trans	-154.1	134.6	153.5	61.2	0	0	0	0	113.5
289	S	35.2	Very low	39.5	Very low	109 Å²	109	139 Å²	139	76%	0.762	74%	0.741	S	S	*	*			trans	90.3	108.1	162.5	77.5	0	0	0	0	121.5
290	L	40.5	Very low	40.1	Very low	161 Å²	161	135 Å²	135	84%	0.843	73%	0.728	S	S	*	*			trans	56.8	99.4	133.9	-83.9	85.1	0	0	0	122.8	S292	L290-S292 PolarHBondContact O-N 2.97Å
291	S	43.5	Very low	40.4	Very low	117 Å²	117	137 Å²	137	82%	0.818	73%	0.728	S	S	*	*	S	Bend		64.3	3.2	113.2	-150.1	0	0	0	0	122.9
292	S	42.5	Very low	40.5	Very low	93 Å²	93	140.1 Å²	140.1	65%	0.65	72%	0.721	S	S	*	*	S	Bend	trans	-111	-24.1	174.8	-115.1	0	0	0	0	115.6	L290 K294 L295 F296	L290-S292 PolarHBondContact O-N 2.97Å; S292-K294 PolarHBondContact O-N 3.39Å; S292-L295 PolarHBondContact O-N 2.82Å; S292-F296 PolarHBondContact O-N 2.97Å
293	E	44.1	Very low	41	Very low	156 Å²	156	135.8 Å²	135.8	73%	0.729	71%	0.707	S	S	*	*	H	α-helix	trans	-68.7	-34.7	-177.7	-87	-177.1	126.4	0	0	113.4	L295 F296 Q297	E293-L295 PolarHBondContact O-N 3.28Å; E293-F296 PolarHBondContact O-N 3.39Å; E293-Q297 WeakPolarHBondContact O-CB 3.11Å; E293-Q297 PolarHBondContact O-N 2.99Å
294	K	44.3	Very low	41.3	Very low	186 Å²	186	135.8 Å²	135.8	81%	0.809	70%	0.704	S	S	*	*	H	α-helix	trans	-67.7	-20.8	-178.3	-78.2	-174.9	179.2	176.7	0	113.9	S292 R298	S292-K294 PolarHBondContact O-N 3.39Å; K294-R298 VanDerWaalsContact O-CB 3.28Å; K294-R298 WeakPolarHBondContact O-CB 3.32Å
295	L	45.3	Very low	41.8	Very low	133 Å²	133	129.1 Å²	129.1	70%	0.696	69%	0.689	S	S	*	*	H	α-helix	trans	-86.7	-37.9	173.8	-96.6	160.9	0	0	0	111.7	S292 E293 R298 S299	S292-L295 PolarHBondContact O-N 2.82Å; E293-L295 PolarHBondContact O-N 3.28Å; L295-R298 PolarHBondContact O-N 3.38Å; L295-S299 PolarHBondContact O-N 3.49Å
296	F	41.1	Very low	42.6	Very low	141 Å²	141	124 Å²	124	62%	0.618	66%	0.664	S	S	*	*	H	α-helix	trans	-68.2	-43.2	176	-165.8	-104.3	0	0	0	112.1	S292 E293 R298 S299 L300	S292-F296 PolarHBondContact O-N 2.97Å; E293-F296 PolarHBondContact O-N 3.39Å; F296-R298 VanDerWaalsContact C-N 3.27Å; F296-R298 PolarHBondContact O-N 3.47Å; F296-S299 PolarHBondContact O-N 2.96Å; F296-L300 HydrophobicContact CD1-CD1 3.89Å; F296-L300 HydrophobicContact CE1-CD1 3.54Å; F296-L300 HydrophobicContact CE1-CG 4.41Å; F296-L300 HydrophobicContact CZ-CD1 4.17Å; F296-L300 PolarHBondContact O-N 3.31Å; F296-L300 VanDerWaalsContact O-N 3.09Å
297	Q	42.9	Very low	43.3	Very low	107 Å²	107	121.6 Å²	121.6	50%	0.5	65%	0.651	S	S	.	*	H	α-helix	trans	-62.4	-33.5	174.9	-145.9	102.5	-14.2	0	0	112.3	E293 N301	E293-Q297 WeakPolarHBondContact O-CB 3.11Å; E293-Q297 PolarHBondContact O-N 2.99Å; Q297-N301 WeakPolarHBondContact O-CB 3.37Å; Q297-N301 PolarHBondContact O-N 3.28Å; Q297-N301 VanDerWaalsContact O-N 3.1Å
298	R	42.6	Very low	43.7	Very low	200 Å²	200	114 Å²	114	76%	0.755	63%	0.626	S	S	*	*	H	α-helix	trans	-80.6	-23.6	180	-156.6	172.3	-170	168.2	2	112.5	K294 L295 F296	K294-R298 VanDerWaalsContact O-CB 3.28Å; K294-R298 WeakPolarHBondContact O-CB 3.32Å; L295-R298 PolarHBondContact O-N 3.38Å; F296-R298 VanDerWaalsContact C-N 3.27Å; F296-R298 PolarHBondContact O-N 3.47Å
299	S	41.1	Very low	44.7	Very low	62 Å²	62	118.7 Å²	118.7	43%	0.434	63%	0.627	S	S	.	*	H	α-helix	trans	-72.3	-46.2	169.3	-164.4	0	0	0	0	111.1	L295 F296 N301 R302	L295-S299 PolarHBondContact O-N 3.49Å; F296-S299 PolarHBondContact O-N 2.96Å; S299-N301 PolarHBondContact O-N 2.76Å; S299-R302 PolarHBondContact O-N 2.95Å
300	L	46	Very low	45.7	Very low	96 Å²	96	122.2 Å²	122.2	50%	0.503	62%	0.624	S	S	.	*	H	α-helix	trans	-68.2	-34.2	179.3	-70	172.6	0	0	0	113.4	F296 R302 T304	F296-L300 HydrophobicContact CD1-CD1 3.89Å; F296-L300 HydrophobicContact CE1-CD1 3.54Å; F296-L300 HydrophobicContact CE1-CG 4.41Å; F296-L300 HydrophobicContact CZ-CD1 4.17Å; F296-L300 PolarHBondContact O-N 3.31Å; F296-L300 VanDerWaalsContact O-N 3.09Å; L300-R302 VanDerWaalsContact C-N 3.29Å; L300-R302 PolarHBondContact O-N 2.62Å; L300-T304 PolarHBondContact O-OG1 2.85Å
301	N	41.1	Very low	46.9	Very low	119 Å²	119	117.6 Å²	117.6	64%	0.636	60%	0.603	S	S	*	*	H	α-helix	trans	-73.9	-15	174.8	-87.3	-9.7	0	0	0	114.4	Q297 S299	Q297-N301 WeakPolarHBondContact O-CB 3.37Å; Q297-N301 PolarHBondContact O-N 3.28Å; Q297-N301 VanDerWaalsContact O-N 3.1Å; S299-N301 PolarHBondContact O-N 2.76Å
302	R	42.8	Very low	47.7	Very low	187 Å²	187	116.5 Å²	116.5	71%	0.706	59%	0.585	S	S	*	*	H	α-helix	trans	-85.4	-26.7	179.4	-161	165.6	72.5	178.5	2.7	112.5	S299 L300	S299-R302 PolarHBondContact O-N 2.95Å; L300-R302 VanDerWaalsContact C-N 3.29Å; L300-R302 PolarHBondContact O-N 2.62Å
303	D	42.6	Very low	48.9	Very low	105 Å²	105	116.9 Å²	116.9	56%	0.561	58%	0.577	S	S	*	*	H	α-helix	trans	-86.2	-27.9	-178.8	-71.3	-28.3	0	0	0	113.5	T306	D303-T306 PolarHBondContact O-OG1 3.44Å
304	T	47.8	Very low	50.1	Low	89 Å²	89	112 Å²	112	55%	0.546	56%	0.561	S	S	.	*	H	α-helix	trans	-72.2	-36	178.9	48.5	0	0	0	0	113.5	L300	L300-T304 PolarHBondContact O-OG1 2.85Å
305	G	47.6	Very low	51.2	Low	51 Å²	51	104 Å²	104	53%	0.526	53%	0.526	S	S	.	.	H	α-helix	trans	-74.4	-25.2	179.9	0	0	0	0	0	115.1	R309	G305-R309 WeakPolarHBondContact O-CB 3.38Å
306	T	49.6	Very low	52.3	Low	62 Å²	62	99.5 Å²	99.5	38%	0.38	51%	0.506	S	S	.	.	H	α-helix	trans	-83.4	-33.7	179.7	58.3	0	0	0	0	112.1	D303 R310	D303-T306 PolarHBondContact O-OG1 3.44Å; T306-R310 WeakPolarHBondContact O-CB 3.12Å; T306-R310 VanDerWaalsContact O-CG 3.24Å; T306-R310 WeakPolarHBondContact O-CG 3.5Å; T306-R310 PolarHBondContact O-N 2.86Å; T306-R310 VanDerWaalsContact O-N 3.07Å
307	S	50.3	Low	53.8	Low	72 Å²	72	96.8 Å²	96.8	50%	0.503	50%	0.498	S	S	.	.	H	α-helix	trans	-67.8	-49.4	178.5	-155.6	0	0	0	0	111.8	R309 R310 T311	S307-R309 PolarHBondContact O-N 3.46Å; S307-R310 PolarHBondContact O-N 3.2Å; S307-T311 PolarHBondContact O-N 2.93Å; S307-T311 PolarHBondContact O-OG1 3.06Å; S307-T311 VanDerWaalsContact O-OG1 3.05Å
308	G	53.1	Low	55.2	Low	41 Å²	41	95.8 Å²	95.8	42%	0.423	49%	0.493	S	S	.	.	H	α-helix	trans	-62.7	-36.8	176.8	0	0	0	0	0	113.9	T311 M312	G308-T311 PolarHBondContact O-N 3.41Å; G308-M312 PolarHBondContact O-N 3.04Å
309	R	55	Low	56.6	Low	206 Å²	206	89.8 Å²	89.8	78%	0.777	47%	0.474	S	S	*	.	H	α-helix	trans	-68.8	-34.8	175.7	-166.9	173.6	-179.4	170.9	0.8	112.5	G305 S307 Q313	G305-R309 WeakPolarHBondContact O-CB 3.38Å; S307-R309 PolarHBondContact O-N 3.46Å; R309-Q313 WeakPolarHBondContact O-CB 3.24Å; R309-Q313 PolarHBondContact O-N 3.42Å
310	R	56.6	Low	58.2	Low	183 Å²	183	92.8 Å²	92.8	69%	0.691	48%	0.479	S	S	*	.	H	α-helix	trans	-68.2	-40.5	172.8	-75.3	173.4	-174	168.3	3.9	111.4	T306 S307 Q313 S314	T306-R310 WeakPolarHBondContact O-CB 3.12Å; T306-R310 VanDerWaalsContact O-CG 3.24Å; T306-R310 WeakPolarHBondContact O-CG 3.5Å; T306-R310 PolarHBondContact O-N 2.86Å; T306-R310 VanDerWaalsContact O-N 3.07Å; S307-R310 PolarHBondContact O-N 3.2Å; R310-Q313 PolarHBondContact O-N 3.1Å; R310-S314 PolarHBondContact O-N 3.41Å
311	T	64.6	Low	59.5	Low	64 Å²	64	90.7 Å²	90.7	39%	0.393	48%	0.476	S	S	.	.	H	α-helix	trans	-64.3	-48.1	176	-50.7	0	0	0	0	111.5	S307 G308 Q313 S314 I315	S307-T311 PolarHBondContact O-N 2.93Å; S307-T311 PolarHBondContact O-OG1 3.06Å; S307-T311 VanDerWaalsContact O-OG1 3.05Å; G308-T311 PolarHBondContact O-N 3.41Å; T311-Q313 VanDerWaalsContact C-N 3.33Å; T311-Q313 PolarHBondContact O-N 2.94Å; T311-S314 PolarHBondContact O-N 3.34Å; T311-S314 VanDerWaalsContact O-N 3.14Å; T311-S314 PolarHBondContact O-OG 3.35Å; T311-I315 HydrophobicContact CG2-CD1 4.16Å; T311-I315 WeakPolarHBondContact O-CG1 3.32Å; T311-I315 PolarHBondContact O-N 3.16Å
312	M	61.6	Low	61.1	Low	93 Å²	93	85.6 Å²	85.6	46%	0.458	45%	0.449	S	S	.	.	H	α-helix	trans	-61.5	-38.1	174.9	-78.3	-144.9	93	0	0	113.1	V270 G308 S314 I315 S316	V270-M312 HydrophobicContact CG2-CE 4.07Å; G308-M312 PolarHBondContact O-N 3.04Å; M312-S314 VanDerWaalsContact C-N 3.34Å; M312-I315 PolarHBondContact O-N 3.11Å; M312-S316 WeakPolarHBondContact O-CB 3.47Å; M312-S316 PolarHBondContact O-N 3.39Å
313	Q	67.4	Low	62.8	Low	101 Å²	101	83.4 Å²	83.4	47%	0.472	45%	0.445	S	S	.	.	H	α-helix	trans	-66.1	-37.9	175.8	-171.3	64.2	52	0	0	111.6	R309 R310 T311 N317	R309-Q313 WeakPolarHBondContact O-CB 3.24Å; R309-Q313 PolarHBondContact O-N 3.42Å; R310-Q313 PolarHBondContact O-N 3.1Å; T311-Q313 VanDerWaalsContact C-N 3.33Å; T311-Q313 PolarHBondContact O-N 2.94Å; Q313-N317 PolarHBondContact NE2-OD1 2.89Å; Q313-N317 VanDerWaalsContact NE2-OD1 3.08Å; Q313-N317 WeakPolarHBondContact O-CB 3.39Å; Q313-N317 PolarHBondContact O-N 3.43Å; Q313-N317 PolarHBondContact O-ND2 3.42Å; Q313-N317 PolarHBondContact O-OD1 3.35Å
314	S	68.1	Low	64.5	Low	55 Å²	55	79.6 Å²	79.6	39%	0.385	43%	0.425	S	S	.	.	H	α-helix	trans	-64	-45.7	175.2	73.1	0	0	0	0	111.7	R310 T311 M312 S316 N317 E318	R310-S314 PolarHBondContact O-N 3.41Å; T311-S314 PolarHBondContact O-N 3.34Å; T311-S314 VanDerWaalsContact O-N 3.14Å; T311-S314 PolarHBondContact O-OG 3.35Å; M312-S314 VanDerWaalsContact C-N 3.34Å; S314-S316 PolarHBondContact O-N 2.86Å; S314-N317 WeakPolarHBondContact O-CB 3.46Å; S314-N317 PolarHBondContact O-N 2.89Å; S314-N317 VanDerWaalsContact O-N 3.16Å; S314-E318 WeakPolarHBondContact O-CG 3.28Å; S314-E318 PolarHBondContact O-N 3.29Å
315	I	68.4	Low	65.9	Low	17 Å²	17	76.3 Å²	76.3	9%	0.087	40%	0.404	C	S	.	.	H	α-helix	trans	-62.2	-44.2	176.6	-65.3	166.5	0	0	0	111	C269 T311 M312 N317 E318 Q319	C269-I315 HydrophobicContact CB-CD1 4.26Å; C269-I315 WeakPolarHBondContact SG-CD1 3.08Å; T311-I315 HydrophobicContact CG2-CD1 4.16Å; T311-I315 WeakPolarHBondContact O-CG1 3.32Å; T311-I315 PolarHBondContact O-N 3.16Å; M312-I315 PolarHBondContact O-N 3.11Å; I315-N317 VanDerWaalsContact C-N 3.3Å; I315-N317 PolarHBondContact O-N 3.33Å; I315-E318 PolarHBondContact O-N 2.95Å; I315-Q319 WeakPolarHBondContact O-CG 3.38Å; I315-Q319 PolarHBondContact O-N 2.83Å
316	S	68.9	Low	67.5	Low	39 Å²	39	74.1 Å²	74.1	27%	0.273	38%	0.382	S	S	.	.	H	α-helix	trans	-62.8	-36.9	176.4	-176.3	0	0	0	0	112.4	M312 S314 K320	M312-S316 WeakPolarHBondContact O-CB 3.47Å; M312-S316 PolarHBondContact O-N 3.39Å; S314-S316 PolarHBondContact O-N 2.86Å; S316-K320 WeakPolarHBondContact O-CG 3.48Å; S316-K320 PolarHBondContact O-N 3.19Å
317	N	71.6	Confident	69.2	Low	83 Å²	83	73.4 Å²	73.4	44%	0.444	38%	0.375	S	S	.	.	H	α-helix	trans	-68.2	-39.3	175.8	-67.8	-15.7	0	0	0	111.4	Q313 S314 I315 K320 A321	Q313-N317 PolarHBondContact NE2-OD1 2.89Å; Q313-N317 VanDerWaalsContact NE2-OD1 3.08Å; Q313-N317 WeakPolarHBondContact O-CB 3.39Å; Q313-N317 PolarHBondContact O-N 3.43Å; Q313-N317 PolarHBondContact O-ND2 3.42Å; Q313-N317 PolarHBondContact O-OD1 3.35Å; S314-N317 WeakPolarHBondContact O-CB 3.46Å; S314-N317 PolarHBondContact O-N 2.89Å; S314-N317 VanDerWaalsContact O-N 3.16Å; I315-N317 VanDerWaalsContact C-N 3.3Å; I315-N317 PolarHBondContact O-N 3.33Å; N317-K320 PolarHBondContact O-N 3.02Å; N317-A321 PolarHBondContact O-N 3.39Å
318	E	71.6	Confident	70.8	Confident	87 Å²	87	70.1 Å²	70.1	41%	0.407	35%	0.352	S	S	.	.	H	α-helix	trans	-67.3	-39.5	175	-71	-166.2	176.3	0	0	112.6	L262 S314 I315 K320 A321 S322	L262-E318 HydrophobicContact CD2-CB 4.47Å; S314-E318 WeakPolarHBondContact O-CG 3.28Å; S314-E318 PolarHBondContact O-N 3.29Å; I315-E318 PolarHBondContact O-N 2.95Å; E318-K320 VanDerWaalsContact C-N 3.33Å; E318-K320 PolarHBondContact O-N 2.91Å; E318-A321 PolarHBondContact O-N 2.95Å; E318-S322 WeakPolarHBondContact O-CB 3.22Å; E318-S322 PolarHBondContact O-N 2.95Å; E318-S322 PolarHBondContact O-OG 3.07Å; E318-S322 VanDerWaalsContact O-OG 3.1Å
319	Q	73.6	Confident	72.4	Confident	74 Å²	74	68.7 Å²	68.7	35%	0.346	33%	0.334	S	S	.	.	H	α-helix	trans	-60.5	-42.2	172	-75.2	179.4	-17.5	0	0	112	L262 I315 S322 K323	L262-Q319 HydrophobicContact CB-CG 4.39Å; L262-Q319 HydrophobicContact CD2-CG 4.47Å; I315-Q319 WeakPolarHBondContact O-CG 3.38Å; I315-Q319 PolarHBondContact O-N 2.83Å; Q319-S322 PolarHBondContact O-N 3.39Å; Q319-K323 WeakPolarHBondContact O-CB 3.38Å; Q319-K323 PolarHBondContact O-N 3.17Å
320	K	74.4	Confident	74	Confident	124 Å²	124	65.3 Å²	65.3	54%	0.539	33%	0.325	S	S	.	.	H	α-helix	trans	-62.3	-47.2	174.9	-73.6	170.1	-173.1	171.3	0	110.9	S316 N317 E318 S322 K323 V324	S316-K320 WeakPolarHBondContact O-CG 3.48Å; S316-K320 PolarHBondContact O-N 3.19Å; N317-K320 PolarHBondContact O-N 3.02Å; E318-K320 VanDerWaalsContact C-N 3.33Å; E318-K320 PolarHBondContact O-N 2.91Å; K320-S322 PolarHBondContact O-N 2.9Å; K320-K323 PolarHBondContact O-N 3.27Å; K320-V324 WeakPolarHBondContact O-CG2 3.43Å; K320-V324 PolarHBondContact O-N 2.76Å; K320-V324 VanDerWaalsContact O-N 3.14Å
321	A	72.1	Confident	75.7	Confident	53 Å²	53	59 Å²	59	44%	0.438	31%	0.305	S	S	.	.	H	α-helix	trans	-60.7	-44.4	178.2	0	0	0	0	0	112.2	N317 E318 K323 V324 L325	N317-A321 PolarHBondContact O-N 3.39Å; E318-A321 PolarHBondContact O-N 2.95Å; A321-K323 VanDerWaalsContact C-N 3.34Å; A321-K323 PolarHBondContact O-N 2.99Å; A321-V324 PolarHBondContact O-N 3.43Å; A321-L325 PolarHBondContact O-N 3.36Å; A321-L325 VanDerWaalsContact O-N 3.12Å
322	S	76	Confident	76.9	Confident	11 Å²	11	56.6 Å²	56.6	8%	0.077	29%	0.289	C	S	.	.	H	α-helix	trans	-65.3	-35	177	-64.6	0	0	0	0	112.7	L262 E318 Q319 K320 L325 G326	L262-S322 WeakPolarHBondContact CD1-OG 3.26Å; E318-S322 WeakPolarHBondContact O-CB 3.22Å; E318-S322 PolarHBondContact O-N 2.95Å; E318-S322 PolarHBondContact O-OG 3.07Å; E318-S322 VanDerWaalsContact O-OG 3.1Å; Q319-S322 PolarHBondContact O-N 3.39Å; K320-S322 PolarHBondContact O-N 2.9Å; S322-L325 PolarHBondContact O-N 3.26Å; S322-G326 PolarHBondContact O-N 3.05Å
323	K	78.7	Confident	78.2	Confident	141 Å²	141	53.7 Å²	53.7	61%	0.613	28%	0.277	S	S	*	.	H	α-helix	trans	-62.8	-41.2	173	-176.1	176	179.7	175.5	0	111.9	Q319 K320 A321 G326 I327	Q319-K323 WeakPolarHBondContact O-CB 3.38Å; Q319-K323 PolarHBondContact O-N 3.17Å; K320-K323 PolarHBondContact O-N 3.27Å; A321-K323 VanDerWaalsContact C-N 3.34Å; A321-K323 PolarHBondContact O-N 2.99Å; K323-G326 PolarHBondContact O-N 2.97Å; K323-I327 HydrophobicContact CG-CD1 4.44Å; K323-I327 WeakPolarHBondContact O-CG1 3.34Å; K323-I327 PolarHBondContact O-N 3.46Å
324	V	77.9	Confident	79.5	Confident	26 Å²	26	52.5 Å²	52.5	16%	0.158	28%	0.276	C	S	.	.	H	α-helix	trans	-63.1	-47.6	177.5	178.8	0	0	0	0	110.8	K320 A321 G326 I327 V328 V379 F383	K320-V324 WeakPolarHBondContact O-CG2 3.43Å; K320-V324 PolarHBondContact O-N 2.76Å; K320-V324 VanDerWaalsContact O-N 3.14Å; A321-V324 PolarHBondContact O-N 3.43Å; V324-G326 VanDerWaalsContact C-N 3.29Å; V324-G326 PolarHBondContact O-N 3.47Å; V324-I327 PolarHBondContact O-N 2.97Å; V324-I327 VanDerWaalsContact O-N 3.16Å; V324-V328 WeakPolarHBondContact O-CG2 3.32Å; V324-V328 PolarHBondContact O-N 3.47Å; V324-V328 VanDerWaalsContact O-N 3.1Å; V324-V379 HydrophobicContact CG1-CG1 4.08Å; V324-F383 HydrophobicContact CB-CB 4.2Å; V324-F383 HydrophobicContact CG1-CB 3.84Å; V324-F383 HydrophobicContact CG1-CD2 4.25Å; V324-F383 HydrophobicContact CG1-CG 4.31Å; V324-F383 HydrophobicContact CG2-CB 3.23Å; V324-F383 HydrophobicContact CG2-CD1 4.24Å; V324-F383 HydrophobicContact CG2-CD2 4.39Å; V324-F383 HydrophobicContact CG2-CG 3.74Å
325	L	77.6	Confident	80.8	Confident	19 Å²	19	51.2 Å²	51.2	10%	0.099	26%	0.264	C	S	.	.	H	α-helix	trans	-60.7	-40.1	176.5	-68.6	172.7	0	0	0	111.7	I170 R174 A321 S322 I327 V328 F329	I170-L325 HydrophobicContact CG2-CD1 4.02Å; I170-L325 HydrophobicContact CG2-CD2 3.84Å; R174-L325 HydrophobicContact CG-CD1 3.56Å; A321-L325 PolarHBondContact O-N 3.36Å; A321-L325 VanDerWaalsContact O-N 3.12Å; S322-L325 PolarHBondContact O-N 3.26Å; L325-I327 VanDerWaalsContact C-N 3.33Å; L325-I327 PolarHBondContact O-N 3.44Å; L325-V328 WeakPolarHBondContact O-CB 3.44Å; L325-V328 PolarHBondContact O-N 3.05Å; L325-F329 HydrophobicContact CB-CE2 4.13Å; L325-F329 HydrophobicContact CB-CZ 4.05Å; L325-F329 WeakPolarHBondContact O-CD1 3.48Å; L325-F329 WeakPolarHBondContact O-CD2 3.41Å; L325-F329 WeakPolarHBondContact O-CG 3.42Å; L325-F329 PolarHBondContact O-N 2.92Å
326	G	81.6	Confident	82.1	Confident	5 Å²	5	50.9 Å²	50.9	5%	0.052	26%	0.262	C	S	.	.	H	α-helix	trans	-59.6	-38.7	173.8	0	0	0	0	0	114.2	S322 K323 V324 F329 F330	S322-G326 PolarHBondContact O-N 3.05Å; K323-G326 PolarHBondContact O-N 2.97Å; V324-G326 VanDerWaalsContact C-N 3.29Å; V324-G326 PolarHBondContact O-N 3.47Å; G326-F329 PolarHBondContact O-N 2.94Å; G326-F330 WeakPolarHBondContact O-CB 3.29Å; G326-F330 PolarHBondContact O-N 3.3Å
327	I	83.9	Confident	83.3	Confident	48 Å²	48	50.2 Å²	50.2	25%	0.246	26%	0.257	C	S	.	.	H	α-helix	trans	-65.3	-45.2	174.6	-67.8	166.9	0	0	0	110.5	K323 V324 L325 F329 F330 L331 V379 F383	K323-I327 HydrophobicContact CG-CD1 4.44Å; K323-I327 WeakPolarHBondContact O-CG1 3.34Å; K323-I327 PolarHBondContact O-N 3.46Å; V324-I327 PolarHBondContact O-N 2.97Å; V324-I327 VanDerWaalsContact O-N 3.16Å; L325-I327 VanDerWaalsContact C-N 3.33Å; L325-I327 PolarHBondContact O-N 3.44Å; I327-F329 VanDerWaalsContact C-N 3.32Å; I327-F329 PolarHBondContact O-N 3.28Å; I327-F330 PolarHBondContact O-N 3.23Å; I327-L331 HydrophobicContact CG2-CD1 3.77Å; I327-L331 HydrophobicContact CG2-CG 4.31Å; I327-L331 WeakPolarHBondContact O-CB 3.3Å; I327-L331 VanDerWaalsContact O-CG 3.29Å; I327-L331 WeakPolarHBondContact O-CG 3.47Å; I327-L331 PolarHBondContact O-N 2.93Å; I327-V379 HydrophobicContact CG2-CG1 4.42Å; I327-F383 HydrophobicContact CD1-CE1 4.04Å; I327-F383 HydrophobicContact CD1-CE2 3.86Å; I327-F383 HydrophobicContact CD1-CZ 3.54Å; I327-F383 HydrophobicContact CG2-CE2 4.41Å
328	V	85.1	Confident	84.5	Confident	2 Å²	2	48 Å²	48	1%	0.012	25%	0.247	C	C	.	.	H	α-helix	trans	-57.3	-47.8	176.2	177.5	0	0	0	0	110.5	L167 V324 L325 L331 F332 V379 Y380	L167-V328 HydrophobicContact CD2-CG1 3.8Å; V324-V328 WeakPolarHBondContact O-CG2 3.32Å; V324-V328 PolarHBondContact O-N 3.47Å; V324-V328 VanDerWaalsContact O-N 3.1Å; L325-V328 WeakPolarHBondContact O-CB 3.44Å; L325-V328 PolarHBondContact O-N 3.05Å; V328-L331 PolarHBondContact O-N 3Å; V328-F332 PolarHBondContact O-N 3.24Å; V328-V379 HydrophobicContact CG2-CB 4.12Å; V328-V379 HydrophobicContact CG2-CG1 3.53Å; V328-Y380 HydrophobicContact CG2-CE1 4.12Å
329	F	86.4	Confident	85.7	Confident	11 Å²	11	45.8 Å²	45.8	5%	0.048	24%	0.236	C	C	.	.	H	α-helix	trans	-61.3	-48.8	179.3	-58.4	-22.1	0	0	0	111.5	L167 I170 M251 Y255 L325 G326 I327 L331 F332 V333	L167-F329 HydrophobicContact CB-CD1 4.15Å; L167-F329 HydrophobicContact CB-CE1 3.99Å; L167-F329 HydrophobicContact CD2-CD1 4.02Å; L167-F329 HydrophobicContact CD2-CE1 3.86Å; L167-F329 HydrophobicContact CG-CD1 4.49Å; L167-F329 HydrophobicContact CG-CE1 4.49Å; I170-F329 HydrophobicContact CG2-CZ 4.35Å; M251-F329 HydrophobicContact CE-CB 4.08Å; M251-F329 HydrophobicContact CG-CB 4.33Å; M251-F329 HydrophobicContact CG-CD1 4.32Å; M251-F329 HydrophobicContact CG-CD2 4.1Å; M251-F329 HydrophobicContact CG-CG 4Å; M251-F329 HydrophobicContact SD-CB 3.7Å; M251-F329 HydrophobicContact SD-CD1 3.59Å; M251-F329 VanDerWaalsContact SD-CD1 3.59Å; M251-F329 HydrophobicContact SD-CD2 4.31Å; M251-F329 HydrophobicContact SD-CE1 4.29Å; M251-F329 HydrophobicContact SD-CG 3.61Å; Y255-F329 HydrophobicContact CD2-CD2 4.09Å; Y255-F329 HydrophobicContact CD2-CE2 4.39Å; L325-F329 HydrophobicContact CB-CE2 4.13Å; L325-F329 HydrophobicContact CB-CZ 4.05Å; L325-F329 WeakPolarHBondContact O-CD1 3.48Å; L325-F329 WeakPolarHBondContact O-CD2 3.41Å; L325-F329 WeakPolarHBondContact O-CG 3.42Å; L325-F329 PolarHBondContact O-N 2.92Å; G326-F329 PolarHBondContact O-N 2.94Å; I327-F329 VanDerWaalsContact C-N 3.32Å; I327-F329 PolarHBondContact O-N 3.28Å; F329-L331 PolarHBondContact O-N 3.39Å; F329-F332 WeakPolarHBondContact O-CB 3.46Å; F329-F332 PolarHBondContact O-N 2.91Å; F329-V333 WeakPolarHBondContact O-CG2 3.15Å; F329-V333 PolarHBondContact O-N 2.02Å
330	F	88.5	Confident	86.7	Confident	136 Å²	136	43.5 Å²	43.5	60%	0.596	23%	0.225	S	C	*	.	H	α-helix	trans	-59.9	-44.2	179.4	177.9	-101	0	0	0	112.5	G326 I327 F332 V333 V334	G326-F330 WeakPolarHBondContact O-CB 3.29Å; G326-F330 PolarHBondContact O-N 3.3Å; I327-F330 PolarHBondContact O-N 3.23Å; F330-F332 VanDerWaalsContact C-N 3.33Å; F330-F332 PolarHBondContact O-N 2.7Å; F330-V333 PolarHBondContact O-N 2.94Å; F330-V334 HydrophobicContact CD1-CG2 4.24Å; F330-V334 HydrophobicContact CD2-CG2 4.33Å; F330-V334 HydrophobicContact CE1-CG2 3.78Å; F330-V334 HydrophobicContact CE2-CG2 3.88Å; F330-V334 HydrophobicContact CZ-CG2 3.58Å; F330-V334 WeakPolarHBondContact O-CG2 3.38Å; F330-V334 PolarHBondContact O-N 3.47Å
331	L	91.4	Very high	87.7	Confident	50 Å²	50	42.4 Å²	42.4	26%	0.262	22%	0.224	S	C	.	.	H	α-helix	trans	-61.9	-41.5	177.5	-71.1	170.5	0	0	0	111.7	I327 V328 F329 V333 V334 M335 V375 V379	I327-L331 HydrophobicContact CG2-CD1 3.77Å; I327-L331 HydrophobicContact CG2-CG 4.31Å; I327-L331 WeakPolarHBondContact O-CB 3.3Å; I327-L331 VanDerWaalsContact O-CG 3.29Å; I327-L331 WeakPolarHBondContact O-CG 3.47Å; I327-L331 PolarHBondContact O-N 2.93Å; V328-L331 PolarHBondContact O-N 3Å; F329-L331 PolarHBondContact O-N 3.39Å; L331-V333 PolarHBondContact O-N 2.83Å; L331-V334 PolarHBondContact O-N 3.16Å; L331-M335 HydrophobicContact CD2-CE 4.36Å; L331-M335 WeakPolarHBondContact O-CB 3.44Å; L331-M335 VanDerWaalsContact O-CG 3.26Å; L331-M335 WeakPolarHBondContact O-CG 3.3Å; L331-M335 PolarHBondContact O-N 2.86Å; L331-V375 HydrophobicContact CD1-CG1 3.85Å; L331-V379 HydrophobicContact CD1-CG2 3.79Å
332	F	89.4	Confident	88.8	Confident	13 Å²	13	40.3 Å²	40.3	6%	0.057	21%	0.206	C	C	.	.	H	α-helix	trans	-59.2	-47	175.3	-177.2	-87.2	0	0	0	111.9	I164 L167 F244 V328 F329 F330 M335 W336	I164-F332 HydrophobicContact CB-CE1 3.93Å; I164-F332 HydrophobicContact CB-CZ 3.68Å; I164-F332 HydrophobicContact CD1-CE1 3.7Å; I164-F332 HydrophobicContact CD1-CZ 4.23Å; I164-F332 HydrophobicContact CG1-CE1 3.71Å; I164-F332 HydrophobicContact CG1-CZ 4.03Å; L167-F332 HydrophobicContact CD1-CB 3.94Å; L167-F332 HydrophobicContact CD1-CD1 4.21Å; L167-F332 HydrophobicContact CD1-CD2 3.65Å; L167-F332 HydrophobicContact CD1-CE2 4.23Å; L167-F332 HydrophobicContact CD1-CG 3.65Å; F244-F332 HydrophobicContact CD2-CE1 4.44Å; F244-F332 AromaticContact CE2-CE1 3.99Å; F244-F332 HydrophobicContact CE2-CE1 3.99Å; V328-F332 PolarHBondContact O-N 3.24Å; F329-F332 WeakPolarHBondContact O-CB 3.46Å; F329-F332 PolarHBondContact O-N 2.91Å; F330-F332 VanDerWaalsContact C-N 3.33Å; F330-F332 PolarHBondContact O-N 2.7Å; F332-M335 PolarHBondContact O-N 2.9Å; F332-W336 AromaticContact CD2-CD1 3.59Å; F332-W336 AromaticContact CD2-NE1 3.84Å; F332-W336 HydrophobicContact CE1-CB 4.44Å; F332-W336 AromaticContact CE1-CD1 3.86Å; F332-W336 HydrophobicContact CE1-CG 4.29Å; F332-W336 AromaticContact CE2-CD1 3.27Å; F332-W336 HydrophobicContact CE2-CG 4.26Å; F332-W336 AromaticContact CE2-NE1 3.3Å; F332-W336 VanDerWaalsContact CE2-NE1 3.3Å; F332-W336 AromaticContact CZ-CD1 3.4Å; F332-W336 VanDerWaalsContact CZ-CD1 3.4Å; F332-W336 AromaticContact CZ-CG 3.99Å; F332-W336 HydrophobicContact CZ-CG 3.99Å; F332-W336 AromaticContact CZ-NE1 3.71Å; F332-W336 PolarHBondContact O-N 3.08Å
333	V	90	Very high	89.6	Confident	33 Å²	33	41.3 Å²	41.3	20%	0.2	21%	0.21	C	C	.	.	H	α-helix	trans	-59.8	-50.1	177.8	179.6	0	0	0	0	111.1	L248 M251 F329 F330 L331 M335 W336 C337	L248-V333 HydrophobicContact CD1-CB 4.32Å; L248-V333 HydrophobicContact CD1-CG1 4.16Å; L248-V333 HydrophobicContact CD1-CG2 3.3Å; M251-V333 HydrophobicContact CE-CG2 3.71Å; F329-V333 WeakPolarHBondContact O-CG2 3.15Å; F329-V333 PolarHBondContact O-N 2.02Å; F330-V333 PolarHBondContact O-N 2.94Å; L331-V333 PolarHBondContact O-N 2.83Å; V333-M335 PolarHBondContact O-N 3.33Å; V333-W336 PolarHBondContact O-N 3.31Å; V333-C337 WeakPolarHBondContact CG1-SG 3.44Å; V333-C337 WeakPolarHBondContact O-CB 3.26Å; V333-C337 PolarHBondContact O-N 3.18Å; V333-C337 PolarHBondContact O-SG 2.9Å
334	V	94.4	Very high	90.3	Very high	76 Å²	76	35.6 Å²	35.6	46%	0.461	19%	0.188	S	C	.	.	H	α-helix	trans	-62.1	-35.3	-177.3	170.6	0	0	0	0	111.7	F330 L331 P338	F330-V334 HydrophobicContact CD1-CG2 4.24Å; F330-V334 HydrophobicContact CD2-CG2 4.33Å; F330-V334 HydrophobicContact CE1-CG2 3.78Å; F330-V334 HydrophobicContact CE2-CG2 3.88Å; F330-V334 HydrophobicContact CZ-CG2 3.58Å; F330-V334 WeakPolarHBondContact O-CG2 3.38Å; F330-V334 PolarHBondContact O-N 3.47Å; L331-V334 PolarHBondContact O-N 3.16Å; V334-P338 WeakPolarHBondContact O-CD 3.35Å
335	M	95.8	Very high	91	Very high	27 Å²	27	38 Å²	38	13%	0.133	20%	0.198	C	C	.	.	H	α-helix	trans	-80.3	-34	-177.8	-71	173	-179.1	0	0	113.4	L331 F332 V333 I368 S372 V375	L331-M335 HydrophobicContact CD2-CE 4.36Å; L331-M335 WeakPolarHBondContact O-CB 3.44Å; L331-M335 VanDerWaalsContact O-CG 3.26Å; L331-M335 WeakPolarHBondContact O-CG 3.3Å; L331-M335 PolarHBondContact O-N 2.86Å; F332-M335 PolarHBondContact O-N 2.9Å; V333-M335 PolarHBondContact O-N 3.33Å; M335-I368 HydrophobicContact CB-CG2 4.1Å; M335-I368 HydrophobicContact CG-CG2 4.18Å; M335-S372 WeakPolarHBondContact SD-CA 3.4Å; M335-V375 HydrophobicContact CE-CG2 3.99Å; M335-V375 HydrophobicContact SD-CG2 4.35Å
336	W	95.6	Very high	91.6	Very high	11 Å²	11	38.6 Å²	38.6	4%	0.042	21%	0.206	C	C	.	.	H	α-helix	trans	-94.9	-29.1	-177.7	-79.8	100.9	0	0	0	114.9	F244 F332 V333 P338 F339 F340 G369 Y370 S372	F244-W336 HydrophobicContact CE2-CB 3.58Å; F244-W336 HydrophobicContact CE2-CG 4.48Å; F244-W336 HydrophobicContact CZ-CB 4.03Å; F332-W336 AromaticContact CD2-CD1 3.59Å; F332-W336 AromaticContact CD2-NE1 3.84Å; F332-W336 HydrophobicContact CE1-CB 4.44Å; F332-W336 AromaticContact CE1-CD1 3.86Å; F332-W336 HydrophobicContact CE1-CG 4.29Å; F332-W336 AromaticContact CE2-CD1 3.27Å; F332-W336 HydrophobicContact CE2-CG 4.26Å; F332-W336 AromaticContact CE2-NE1 3.3Å; F332-W336 VanDerWaalsContact CE2-NE1 3.3Å; F332-W336 AromaticContact CZ-CD1 3.4Å; F332-W336 VanDerWaalsContact CZ-CD1 3.4Å; F332-W336 AromaticContact CZ-CG 3.99Å; F332-W336 HydrophobicContact CZ-CG 3.99Å; F332-W336 AromaticContact CZ-NE1 3.71Å; F332-W336 PolarHBondContact O-N 3.08Å; V333-W336 PolarHBondContact O-N 3.31Å; W336-P338 VanDerWaalsContact C-CD 3.46Å; W336-F339 HydrophobicContact CE3-CD1 4.32Å; W336-F339 HydrophobicContact CZ3-CD1 4.31Å; W336-F339 PolarHBondContact O-N 3.06Å; W336-F340 HydrophobicContact CB-CD2 4.26Å; W336-F340 HydrophobicContact CB-CE2 4.34Å; W336-F340 HydrophobicContact CD2-CE2 4.32Å; W336-F340 HydrophobicContact CE3-CD2 4.27Å; W336-F340 AromaticContact CE3-CE2 3.67Å; W336-F340 HydrophobicContact CE3-CE2 3.67Å; W336-F340 HydrophobicContact CZ3-CE2 4.36Å; W336-F340 WeakPolarHBondContact O-CD2 3.33Å; W336-F340 PolarHBondContact O-N 3.26Å; W336-G369 PolarHBondContact NE1-O 3.18Å; W336-Y370 HydrophobicContact CH2-CD1 4.18Å; W336-Y370 HydrophobicContact CH2-CE1 4.29Å; W336-Y370 HydrophobicContact CZ2-CD1 4.47Å; W336-S372 PolarHBondContact NE1-OG 3.15Å
337	C	94.6	Very high	92	Very high	25 Å²	25	39.3 Å²	39.3	17%	0.169	21%	0.209	C	C	.	.	H	α-helix	trans	-54.4	-43.4	-179.4	-83.9	0	0	0	0	114.1	V333 F339 F340 I341	V333-C337 WeakPolarHBondContact CG1-SG 3.44Å; V333-C337 WeakPolarHBondContact O-CB 3.26Å; V333-C337 PolarHBondContact O-N 3.18Å; V333-C337 PolarHBondContact O-SG 2.9Å; C337-F339 VanDerWaalsContact C-N 3.3Å; C337-F339 PolarHBondContact O-N 3.29Å; C337-F340 PolarHBondContact O-N 3.14Å; C337-I341 HydrophobicContact CB-CD1 4.25Å; C337-I341 WeakPolarHBondContact O-CB 3Å; C337-I341 WeakPolarHBondContact O-CG1 3.46Å; C337-I341 PolarHBondContact O-N 3.22Å
338	P	96.9	Very high	92.3	Very high	37 Å²	37	43 Å²	43	24%	0.24	23%	0.228	C	C	.	.	H	α-helix	trans	-56.1	-45.1	179.1	-26.1	35.5	0	0	0	112.3	V334 W336 T342 F365	V334-P338 WeakPolarHBondContact O-CD 3.35Å; W336-P338 VanDerWaalsContact C-CD 3.46Å; P338-T342 WeakPolarHBondContact O-CB 3.41Å; P338-T342 PolarHBondContact O-N 3.42Å; P338-T342 PolarHBondContact O-OG1 3.27Å; P338-F365 HydrophobicContact CB-CB 4.32Å; P338-F365 HydrophobicContact CB-CD1 3.91Å; P338-F365 HydrophobicContact CB-CD2 3.66Å; P338-F365 HydrophobicContact CB-CE1 4.05Å; P338-F365 HydrophobicContact CB-CE2 3.81Å; P338-F365 HydrophobicContact CB-CG 3.71Å; P338-F365 HydrophobicContact CB-CZ 4Å; P338-F365 WeakPolarHBondContact O-CD2 3.27Å
339	F	95.9	Very high	92.4	Very high	39 Å²	39	44 Å²	44	17%	0.171	23%	0.234	C	C	.	.	H	α-helix	trans	-61.1	-53.9	177.5	175.8	-97.5	0	0	0	111.6	W336 C337 I341 T342 N343 L362 F365 V366	W336-F339 HydrophobicContact CE3-CD1 4.32Å; W336-F339 HydrophobicContact CZ3-CD1 4.31Å; W336-F339 PolarHBondContact O-N 3.06Å; C337-F339 VanDerWaalsContact C-N 3.3Å; C337-F339 PolarHBondContact O-N 3.29Å; F339-I341 VanDerWaalsContact C-N 3.35Å; F339-I341 PolarHBondContact O-N 3.23Å; F339-T342 PolarHBondContact O-N 3.46Å; F339-N343 WeakPolarHBondContact O-CB 3.4Å; F339-N343 PolarHBondContact O-N 3.02Å; F339-L362 HydrophobicContact CD2-CD2 3.86Å; F339-L362 HydrophobicContact CE2-CD2 3.9Å; F339-F365 HydrophobicContact CB-CB 3.88Å; F339-F365 HydrophobicContact CD2-CB 4.48Å; F339-V366 HydrophobicContact CD2-CB 4.01Å; F339-V366 HydrophobicContact CE2-CB 4.01Å; F339-V366 HydrophobicContact CE2-CG2 4.31Å
340	F	95	Very high	92.1	Very high	27 Å²	27	48.5 Å²	48.5	12%	0.118	25%	0.254	C	S	.	.	H	α-helix	trans	-64.9	-37.2	-176.8	-79.8	-77.5	0	0	0	112.9	F244 F245 W336 C337 N343 V344	F244-F340 HydrophobicContact CB-CD1 3.83Å; F244-F340 HydrophobicContact CB-CD2 4.05Å; F244-F340 HydrophobicContact CB-CE1 3.55Å; F244-F340 HydrophobicContact CB-CE2 3.79Å; F244-F340 HydrophobicContact CB-CG 4.08Å; F244-F340 HydrophobicContact CB-CZ 3.53Å; F244-F340 HydrophobicContact CD1-CB 3.79Å; F244-F340 HydrophobicContact CD1-CD1 4.01Å; F244-F340 AromaticContact CD1-CD2 3.53Å; F244-F340 HydrophobicContact CD1-CD2 3.53Å; F244-F340 HydrophobicContact CD1-CE2 4.11Å; F244-F340 AromaticContact CD1-CG 3.48Å; F244-F340 HydrophobicContact CD1-CG 3.48Å; F244-F340 VanDerWaalsContact CD1-CG 3.48Å; F244-F340 AromaticContact CD2-CD2 3.44Å; F244-F340 HydrophobicContact CD2-CD2 3.44Å; F244-F340 VanDerWaalsContact CD2-CD2 3.44Å; F244-F340 AromaticContact CD2-CE2 3.26Å; F244-F340 HydrophobicContact CD2-CE2 3.26Å; F244-F340 HydrophobicContact CD2-CG 4.2Å; F244-F340 AromaticContact CD2-CZ 3.91Å; F244-F340 HydrophobicContact CD2-CZ 3.91Å; F244-F340 HydrophobicContact CE1-CB 3.84Å; F244-F340 AromaticContact CE1-CD2 3.71Å; F244-F340 HydrophobicContact CE1-CD2 3.71Å; F244-F340 AromaticContact CE1-CG 3.88Å; F244-F340 HydrophobicContact CE1-CG 3.88Å; F244-F340 AromaticContact CE2-CD2 3.63Å; F244-F340 HydrophobicContact CE2-CD2 3.63Å; F244-F340 AromaticContact CE2-CE2 3.78Å; F244-F340 HydrophobicContact CE2-CE2 3.78Å; F244-F340 HydrophobicContact CG-CB 4.46Å; F244-F340 AromaticContact CG-CD1 3.96Å; F244-F340 HydrophobicContact CG-CD1 3.96Å; F244-F340 AromaticContact CG-CD2 3.39Å; F244-F340 HydrophobicContact CG-CD2 3.39Å; F244-F340 HydrophobicContact CG-CE1 4.01Å; F244-F340 AromaticContact CG-CE2 3.45Å; F244-F340 HydrophobicContact CG-CE2 3.45Å; F244-F340 VanDerWaalsContact CG-CE2 3.45Å; F244-F340 AromaticContact CG-CG 3.66Å; F244-F340 HydrophobicContact CG-CG 3.66Å; F244-F340 AromaticContact CG-CZ 3.78Å; F244-F340 HydrophobicContact CG-CZ 3.78Å; F244-F340 AromaticContact CZ-CD2 3.76Å; F244-F340 HydrophobicContact CZ-CD2 3.76Å; F244-F340 HydrophobicContact CZ-CE2 4.38Å; F244-F340 HydrophobicContact CZ-CG 4.39Å; F245-F340 HydrophobicContact CZ-CB 4.22Å; W336-F340 HydrophobicContact CB-CD2 4.26Å; W336-F340 HydrophobicContact CB-CE2 4.34Å; W336-F340 HydrophobicContact CD2-CE2 4.32Å; W336-F340 HydrophobicContact CE3-CD2 4.27Å; W336-F340 AromaticContact CE3-CE2 3.67Å; W336-F340 HydrophobicContact CE3-CE2 3.67Å; W336-F340 HydrophobicContact CZ3-CE2 4.36Å; W336-F340 WeakPolarHBondContact O-CD2 3.33Å; W336-F340 PolarHBondContact O-N 3.26Å; C337-F340 PolarHBondContact O-N 3.14Å; F340-N343 PolarHBondContact O-N 3.24Å; F340-V344 WeakPolarHBondContact O-CB 3.44Å; F340-V344 WeakPolarHBondContact O-CG2 3.46Å; F340-V344 PolarHBondContact O-N 2.87Å
341	I	94.8	Very high	91.7	Very high	100 Å²	100	51.2 Å²	51.2	51%	0.513	27%	0.269	S	S	.	.	H	α-helix	trans	-64.2	-49.5	175.5	-68.9	167.8	0	0	0	109.9	C337 F339 N343 V344 M345	C337-I341 HydrophobicContact CB-CD1 4.25Å; C337-I341 WeakPolarHBondContact O-CB 3Å; C337-I341 WeakPolarHBondContact O-CG1 3.46Å; C337-I341 PolarHBondContact O-N 3.22Å; F339-I341 VanDerWaalsContact C-N 3.35Å; F339-I341 PolarHBondContact O-N 3.23Å; I341-N343 VanDerWaalsContact C-N 3.31Å; I341-N343 PolarHBondContact O-N 2.85Å; I341-V344 PolarHBondContact O-N 3.18Å; I341-M345 VanDerWaalsContact O-CB 3.22Å; I341-M345 WeakPolarHBondContact O-CB 3.29Å; I341-M345 PolarHBondContact O-N 2.59Å
342	T	94.8	Very high	91.5	Very high	10 Å²	10	54.6 Å²	54.6	6%	0.061	30%	0.296	C	S	.	.	H	α-helix	trans	-64.6	-36.7	178.7	-59.4	0	0	0	0	111.9	P338 F339 M345 A346 I358 L361 L362 F365	P338-T342 WeakPolarHBondContact O-CB 3.41Å; P338-T342 PolarHBondContact O-N 3.42Å; P338-T342 PolarHBondContact O-OG1 3.27Å; F339-T342 PolarHBondContact O-N 3.46Å; T342-M345 PolarHBondContact O-N 3.04Å; T342-A346 WeakPolarHBondContact O-CB 3.48Å; T342-A346 PolarHBondContact O-N 2.97Å; T342-I358 HydrophobicContact CG2-CG2 4.07Å; T342-L361 HydrophobicContact CG2-CB 4.14Å; T342-L362 HydrophobicContact CG2-CD2 3.74Å; T342-L362 HydrophobicContact CG2-CG 3.84Å; T342-F365 WeakPolarHBondContact OG1-CE2 3.33Å
343	N	93	Very high	91.5	Very high	31 Å²	31	55.7 Å²	55.7	17%	0.166	31%	0.305	C	S	.	.	H	α-helix	trans	-67.3	-44.1	-180	-163.9	30.5	0	0	0	111.6	V236 F339 F340 I341 A346 V347 L362	V236-N343 WeakPolarHBondContact CG1-ND2 3.5Å; F339-N343 WeakPolarHBondContact O-CB 3.4Å; F339-N343 PolarHBondContact O-N 3.02Å; F340-N343 PolarHBondContact O-N 3.24Å; I341-N343 VanDerWaalsContact C-N 3.31Å; I341-N343 PolarHBondContact O-N 2.85Å; N343-A346 WeakPolarHBondContact O-CB 3.18Å; N343-A346 PolarHBondContact O-N 3.31Å; N343-V347 PolarHBondContact O-N 2.57Å; N343-L362 HydrophobicContact CB-CD2 3.96Å
344	V	93.7	Very high	91.6	Very high	22 Å²	22	58.5 Å²	58.5	13%	0.133	32%	0.319	C	S	.	.	H	α-helix	trans	-66.8	-41	173.4	171.3	0	0	0	0	111.1	L237 F245 F340 I341 A346 V347 I348	L237-V344 HydrophobicContact CD2-CG1 4.12Å; F245-V344 HydrophobicContact CE2-CG2 4.08Å; F340-V344 WeakPolarHBondContact O-CB 3.44Å; F340-V344 WeakPolarHBondContact O-CG2 3.46Å; F340-V344 PolarHBondContact O-N 2.87Å; I341-V344 PolarHBondContact O-N 3.18Å; V344-A346 VanDerWaalsContact C-N 3.33Å; V344-A346 PolarHBondContact O-N 3.49Å; V344-V347 PolarHBondContact O-N 3.28Å; V344-I348 HydrophobicContact CG1-CD1 3.61Å; V344-I348 HydrophobicContact CG1-CG1 4.33Å; V344-I348 WeakPolarHBondContact O-CG1 3.29Å; V344-I348 PolarHBondContact O-N 3.03Å; V344-I348 VanDerWaalsContact O-N 3.1Å
345	M	92	Very high	91.2	Very high	77 Å²	77	59.4 Å²	59.4	38%	0.379	32%	0.318	S	S	.	.	H	α-helix	trans	-59.8	-43.7	177	-171.7	178	76.3	0	0	111.2	I341 T342 V347 I348 C349 I358	I341-M345 VanDerWaalsContact O-CB 3.22Å; I341-M345 WeakPolarHBondContact O-CB 3.29Å; I341-M345 PolarHBondContact O-N 2.59Å; T342-M345 PolarHBondContact O-N 3.04Å; M345-V347 PolarHBondContact O-N 3.07Å; M345-I348 PolarHBondContact O-N 3.36Å; M345-C349 PolarHBondContact O-N 3.19Å; M345-C349 PolarHBondContact O-SG 3.18Å; M345-I358 HydrophobicContact CE-CD1 3.96Å; M345-I358 HydrophobicContact CE-CG1 4.16Å
346	A	90.7	Very high	90.9	Very high	31 Å²	31	65.7 Å²	65.7	26%	0.256	35%	0.347	S	S	.	.	H	α-helix	trans	-54.4	-37.8	177.5	0	0	0	0	0	112.9	T342 N343 V344 I358	T342-A346 WeakPolarHBondContact O-CB 3.48Å; T342-A346 PolarHBondContact O-N 2.97Å; N343-A346 WeakPolarHBondContact O-CB 3.18Å; N343-A346 PolarHBondContact O-N 3.31Å; V344-A346 VanDerWaalsContact C-N 3.33Å; V344-A346 PolarHBondContact O-N 3.49Å; A346-I358 HydrophobicContact CB-CD1 4.41Å; A346-I358 HydrophobicContact CB-CG2 3.55Å
347	V	91.1	Very high	90.7	Very high	19 Å²	19	69.2 Å²	69.2	12%	0.115	37%	0.37	C	S	.	.	H	α-helix	trans	-75.9	-38.3	177.9	176.3	0	0	0	0	111.9	E233 V236 L237 N343 V344 M345 K350	E233-V347 HydrophobicContact CB-CG1 3.7Å; E233-V347 HydrophobicContact CG-CG1 3.86Å; V236-V347 HydrophobicContact CB-CG2 4.01Å; V236-V347 HydrophobicContact CG1-CG2 3.63Å; L237-V347 HydrophobicContact CD1-CG1 3.96Å; L237-V347 HydrophobicContact CD2-CG1 4.33Å; L237-V347 HydrophobicContact CG-CG1 4.01Å; N343-V347 PolarHBondContact O-N 2.57Å; V344-V347 PolarHBondContact O-N 3.28Å; M345-V347 PolarHBondContact O-N 3.07Å; V347-K350 WeakPolarHBondContact O-CG 3.42Å
348	I	90.3	Very high	90.6	Very high	126 Å²	126	68.7 Å²	68.7	65%	0.646	37%	0.365	S	S	*	.	H	α-helix	trans	-73.7	-43.9	-176.9	-66.3	170.9	0	0	0	111.6	V344 M345	V344-I348 HydrophobicContact CG1-CD1 3.61Å; V344-I348 HydrophobicContact CG1-CG1 4.33Å; V344-I348 WeakPolarHBondContact O-CG1 3.29Å; V344-I348 PolarHBondContact O-N 3.03Å; V344-I348 VanDerWaalsContact O-N 3.1Å; M345-I348 PolarHBondContact O-N 3.36Å
349	C	87.2	Confident	90.2	Very high	22 Å²	22	68.2 Å²	68.2	15%	0.149	37%	0.367	C	S	.	.	S	Bend	trans	-97.1	7.3	-168.8	66.4	0	0	0	0	115.3	M345 E351 S352 C353	M345-C349 PolarHBondContact O-N 3.19Å; M345-C349 PolarHBondContact O-SG 3.18Å; C349-E351 PolarHBondContact O-N 3.03Å; C349-S352 WeakPolarHBondContact O-CA 3.27Å; C349-S352 WeakPolarHBondContact O-CB 3.48Å; C349-S352 PolarHBondContact O-N 3.45Å; C349-C353 HydrophobicContact CB-CB 3.96Å; C349-C353 WeakPolarHBondContact CB-SG 3.38Å; C349-C353 PolarHBondContact O-N 3.4Å; C349-C353 VanDerWaalsContact O-N 3.16Å; C349-C353 WeakPolarHBondContact SG-CB 3.46Å; C349-C353 CovalentContact SG-SG 2.01Å; C349-C353 PolarHBondContact SG-SG 3.43Å
350	K	79	Confident	90	Very high	106 Å²	106	68 Å²	68	46%	0.461	38%	0.376	S	S	.	.	T	Hydrogen-bonded Turn	trans	14.7	-87.7	174	-55.5	-167.4	-171.1	-162.5	0	115.5	E233 V347	E233-K350 VanDerWaalsContact CD-CE 3.5Å; E233-K350 WeakPolarHBondContact OE1-CE 3.45Å; E233-K350 IonicContact OE1-NZ 2.68Å; E233-K350 PolarHBondContact OE1-NZ 3.23Å; E233-K350 VanDerWaalsContact OE2-CE 3.31Å; E233-K350 WeakPolarHBondContact OE2-CE 3.46Å; E233-K350 IonicContact OE2-NZ 3.62Å; E233-K350 PolarHBondContact OE2-NZ 2.94Å; V347-K350 WeakPolarHBondContact O-CG 3.42Å
351	E	79.9	Confident	90	Very high	194 Å²	194	69.9 Å²	69.9	91%	0.907	39%	0.387	S	S	*	.	T	Hydrogen-bonded Turn	trans	-90.7	-18.1	-176.1	-61.3	-179	177.5	0	0	114.5	C349 C353	C349-E351 PolarHBondContact O-N 3.03Å; E351-C353 VanDerWaalsContact C-N 3.34Å
352	S	88.4	Confident	89.9	Confident	120 Å²	120	66.6 Å²	66.6	84%	0.839	37%	0.37	S	S	*	.	T	Hydrogen-bonded Turn	trans	-78	-19.7	179.2	-57.2	0	0	0	0	113.1	C349	C349-S352 WeakPolarHBondContact O-CA 3.27Å; C349-S352 WeakPolarHBondContact O-CB 3.48Å; C349-S352 PolarHBondContact O-N 3.45Å
353	C	89.7	Confident	89.7	Confident	37 Å²	37	68.6 Å²	68.6	25%	0.25	38%	0.38	C	S	.	.	S	Bend	trans	-106.1	149.8	177.9	-72.1	0	0	0	0	112	C349 E351 E355 I358	C349-C353 HydrophobicContact CB-CB 3.96Å; C349-C353 WeakPolarHBondContact CB-SG 3.38Å; C349-C353 PolarHBondContact O-N 3.4Å; C349-C353 VanDerWaalsContact O-N 3.16Å; C349-C353 WeakPolarHBondContact SG-CB 3.46Å; C349-C353 CovalentContact SG-SG 2.01Å; C349-C353 PolarHBondContact SG-SG 3.43Å; E351-C353 VanDerWaalsContact C-N 3.34Å; C353-E355 PolarHBondContact O-N 2.96Å; C353-I358 HydrophobicContact CB-CD1 3.43Å; C353-I358 VanDerWaalsContact CB-CD1 3.43Å; C353-I358 HydrophobicContact CB-CG1 4.45Å
354	N	91.1	Very high	89.7	Confident	92 Å²	92	71.2 Å²	71.2	49%	0.492	40%	0.397	S	S	.	.			trans	-73.3	109.1	171.3	-172.8	-21.7	0	0	0	110.4	E356 V357 I358	N354-E356 PolarHBondContact O-N 3Å; N354-E356 WeakPolarHBondContact OD1-CB 3.35Å; N354-E356 PolarHBondContact OD1-N 3.35Å; N354-V357 HydrophobicContact CB-CB 4.26Å; N354-V357 HydrophobicContact CB-CG2 4.09Å; N354-V357 PolarHBondContact O-N 2.98Å; N354-I358 PolarHBondContact O-N 2.95Å; N354-I358 VanDerWaalsContact O-N 3.1Å
355	E	86.9	Confident	89.9	Confident	94 Å²	94	72.1 Å²	72.1	44%	0.439	40%	0.399	S	S	.	.	H	α-helix	trans	-57.5	-34.8	178.7	-71.5	-156.8	134.3	0	0	112.9	K224 K225 C353 I358 G359	K224-E355 IonicContact NZ-OE1 2.86Å; K224-E355 PolarHBondContact NZ-OE1 3.26Å; K224-E355 IonicContact NZ-OE2 3.76Å; K225-E355 IonicContact NZ-OE2 2.7Å; C353-E355 PolarHBondContact O-N 2.96Å; E355-I358 PolarHBondContact O-N 2.97Å; E355-G359 PolarHBondContact O-N 3.45Å
356	E	88.1	Confident	90	Very high	160 Å²	160	69.3 Å²	69.3	75%	0.748	39%	0.387	S	S	*	.	H	α-helix	trans	-67.8	-45.2	-177.8	-170.8	-178	179.3	0	0	111	N354 G359 G360	N354-E356 PolarHBondContact O-N 3Å; N354-E356 WeakPolarHBondContact OD1-CB 3.35Å; N354-E356 PolarHBondContact OD1-N 3.35Å; E356-G359 PolarHBondContact O-N 2.68Å; E356-G360 PolarHBondContact O-N 3.16Å
357	V	91.7	Very high	90.3	Very high	84 Å²	84	69.4 Å²	69.4	51%	0.509	38%	0.38	S	S	.	.	H	α-helix	trans	-65.3	-44.2	177.2	177	0	0	0	0	110.5	N354 G360 L361	N354-V357 HydrophobicContact CB-CB 4.26Å; N354-V357 HydrophobicContact CB-CG2 4.09Å; N354-V357 PolarHBondContact O-N 2.98Å; V357-G360 PolarHBondContact O-N 3.5Å; V357-L361 HydrophobicContact CG1-CD1 4.14Å; V357-L361 HydrophobicContact CG1-CG 4.44Å; V357-L361 WeakPolarHBondContact O-CB 3.48Å; V357-L361 VanDerWaalsContact O-CG 3.3Å; V357-L361 WeakPolarHBondContact O-CG 3.37Å; V357-L361 PolarHBondContact O-N 3.47Å
358	I	92.1	Very high	90.5	Very high	15 Å²	15	71.4 Å²	71.4	8%	0.077	39%	0.39	C	S	.	.	H	α-helix	trans	-61.8	-45.5	177.4	-73.9	-174.8	0	0	0	111.1	T342 M345 A346 C353 N354 E355 G360 L361 L362	T342-I358 HydrophobicContact CG2-CG2 4.07Å; M345-I358 HydrophobicContact CE-CD1 3.96Å; M345-I358 HydrophobicContact CE-CG1 4.16Å; A346-I358 HydrophobicContact CB-CD1 4.41Å; A346-I358 HydrophobicContact CB-CG2 3.55Å; C353-I358 HydrophobicContact CB-CD1 3.43Å; C353-I358 VanDerWaalsContact CB-CD1 3.43Å; C353-I358 HydrophobicContact CB-CG1 4.45Å; N354-I358 PolarHBondContact O-N 2.95Å; N354-I358 VanDerWaalsContact O-N 3.1Å; E355-I358 PolarHBondContact O-N 2.97Å; I358-G360 PolarHBondContact O-N 2.95Å; I358-L361 PolarHBondContact O-N 2.67Å; I358-L362 HydrophobicContact CG2-CD1 4.02Å; I358-L362 HydrophobicContact CG2-CG 4.4Å; I358-L362 WeakPolarHBondContact O-CG 3.21Å; I358-L362 PolarHBondContact O-N 3.06Å
359	G	89.5	Confident	90.8	Very high	27 Å²	27	65.4 Å²	65.4	28%	0.278	36%	0.359	S	S	.	.	H	α-helix	trans	-59.6	-45.8	176.8	0	0	0	0	0	112	E355 E356 L361 L362 N363	E355-G359 PolarHBondContact O-N 3.45Å; E356-G359 PolarHBondContact O-N 2.68Å; G359-L361 PolarHBondContact O-N 3.28Å; G359-L362 PolarHBondContact O-N 3.36Å; G359-N363 VanDerWaalsContact O-CG 3.24Å; G359-N363 PolarHBondContact O-N 2.97Å; G359-N363 PolarHBondContact O-ND2 3.25Å
360	G	91	Very high	91.3	Very high	35 Å²	35	64.4 Å²	64.4	36%	0.361	35%	0.352	S	S	.	.	H	α-helix	trans	-59.1	-43.5	174.3	0	0	0	0	0	113.1	E356 V357 I358 N363 V364	E356-G360 PolarHBondContact O-N 3.16Å; V357-G360 PolarHBondContact O-N 3.5Å; I358-G360 PolarHBondContact O-N 2.95Å; G360-N363 PolarHBondContact O-N 3.49Å; G360-V364 WeakPolarHBondContact O-CG2 3.45Å; G360-V364 PolarHBondContact O-N 3.41Å; G360-V364 VanDerWaalsContact O-N 3.15Å
361	L	94.3	Very high	92.1	Very high	66 Å²	66	62.5 Å²	62.5	35%	0.346	35%	0.347	S	S	.	.	H	α-helix	trans	-64.7	-43.1	176.3	-72	174.9	0	0	0	112.3	T342 V357 I358 G359 N363 V364 F365	T342-L361 HydrophobicContact CG2-CB 4.14Å; V357-L361 HydrophobicContact CG1-CD1 4.14Å; V357-L361 HydrophobicContact CG1-CG 4.44Å; V357-L361 WeakPolarHBondContact O-CB 3.48Å; V357-L361 VanDerWaalsContact O-CG 3.3Å; V357-L361 WeakPolarHBondContact O-CG 3.37Å; V357-L361 PolarHBondContact O-N 3.47Å; I358-L361 PolarHBondContact O-N 2.67Å; G359-L361 PolarHBondContact O-N 3.28Å; L361-N363 VanDerWaalsContact C-N 3.33Å; L361-N363 PolarHBondContact O-N 3.17Å; L361-V364 PolarHBondContact O-N 3.24Å; L361-F365 HydrophobicContact CB-CD2 4.27Å; L361-F365 HydrophobicContact CB-CE2 4.02Å; L361-F365 HydrophobicContact CD2-CE1 4.5Å; L361-F365 HydrophobicContact CD2-CE2 4.24Å; L361-F365 HydrophobicContact CD2-CZ 3.93Å; L361-F365 VanDerWaalsContact O-CB 3.32Å; L361-F365 WeakPolarHBondContact O-CB 3.3Å; L361-F365 WeakPolarHBondContact O-CD2 3.44Å; L361-F365 WeakPolarHBondContact O-CG 3.31Å; L361-F365 PolarHBondContact O-N 2.88Å
362	L	92.9	Very high	92.8	Very high	30 Å²	30	53.5 Å²	53.5	16%	0.157	31%	0.305	C	S	.	.	H	α-helix	trans	-61.7	-42.3	176.7	-72.7	174.2	0	0	0	111.6	F339 T342 N343 I358 G359 V364 F365 V366	F339-L362 HydrophobicContact CD2-CD2 3.86Å; F339-L362 HydrophobicContact CE2-CD2 3.9Å; T342-L362 HydrophobicContact CG2-CD2 3.74Å; T342-L362 HydrophobicContact CG2-CG 3.84Å; N343-L362 HydrophobicContact CB-CD2 3.96Å; I358-L362 HydrophobicContact CG2-CD1 4.02Å; I358-L362 HydrophobicContact CG2-CG 4.4Å; I358-L362 WeakPolarHBondContact O-CG 3.21Å; I358-L362 PolarHBondContact O-N 3.06Å; G359-L362 PolarHBondContact O-N 3.36Å; L362-V364 VanDerWaalsContact C-N 3.28Å; L362-V364 PolarHBondContact O-N 3.38Å; L362-F365 PolarHBondContact O-N 2.82Å; L362-V366 WeakPolarHBondContact O-CB 3.42Å; L362-V366 WeakPolarHBondContact O-CG1 3.38Å; L362-V366 PolarHBondContact O-N 3.47Å
363	N	91.4	Very high	93.1	Very high	52 Å²	52	47.9 Å²	47.9	28%	0.278	27%	0.266	S	S	.	.	H	α-helix	trans	-61.4	-34.8	175.7	-71.1	-23.6	0	0	0	112.3	Y140 G359 G360 L361 V366 W367	Y140-N363 HydrophobicContact CE1-CB 4.06Å; Y140-N363 VanDerWaalsContact CE1-CG 3.4Å; Y140-N363 WeakPolarHBondContact CE1-ND2 3.32Å; Y140-N363 WeakPolarHBondContact CE1-OD1 3.46Å; Y140-N363 VanDerWaalsContact CZ-ND2 3.32Å; G359-N363 VanDerWaalsContact O-CG 3.24Å; G359-N363 PolarHBondContact O-N 2.97Å; G359-N363 PolarHBondContact O-ND2 3.25Å; G360-N363 PolarHBondContact O-N 3.49Å; L361-N363 VanDerWaalsContact C-N 3.33Å; L361-N363 PolarHBondContact O-N 3.17Å; N363-V366 WeakPolarHBondContact O-CG1 3.36Å; N363-W367 VanDerWaalsContact O-CD1 3.29Å
364	V	93.8	Very high	93.4	Very high	86 Å²	86	46.8 Å²	46.8	52%	0.521	26%	0.26	S	S	.	.	H	α-helix	trans	-77.2	-47.3	174.5	174.3	0	0	0	0	111.1	G360 L361 L362 V366 W367 I368	G360-V364 WeakPolarHBondContact O-CG2 3.45Å; G360-V364 PolarHBondContact O-N 3.41Å; G360-V364 VanDerWaalsContact O-N 3.15Å; L361-V364 PolarHBondContact O-N 3.24Å; L362-V364 VanDerWaalsContact C-N 3.28Å; L362-V364 PolarHBondContact O-N 3.38Å; V364-V366 VanDerWaalsContact C-N 3.33Å; V364-V366 PolarHBondContact O-N 3.04Å; V364-W367 PolarHBondContact O-N 3.2Å; V364-W367 VanDerWaalsContact O-N 3.17Å; V364-I368 HydrophobicContact CG1-CD1 4.22Å; V364-I368 PolarHBondContact O-N 3.46Å; V364-I368 VanDerWaalsContact O-N 3.15Å
365	F	96.6	Very high	93.6	Very high	41 Å²	41	43.6 Å²	43.6	18%	0.18	24%	0.243	C	C	.	.	H	α-helix	trans	-68.7	-29.6	-173.5	-65.8	-19.2	0	0	0	113.3	P338 F339 T342 L361 L362 W367 I368 G369	P338-F365 HydrophobicContact CB-CB 4.32Å; P338-F365 HydrophobicContact CB-CD1 3.91Å; P338-F365 HydrophobicContact CB-CD2 3.66Å; P338-F365 HydrophobicContact CB-CE1 4.05Å; P338-F365 HydrophobicContact CB-CE2 3.81Å; P338-F365 HydrophobicContact CB-CG 3.71Å; P338-F365 HydrophobicContact CB-CZ 4Å; P338-F365 WeakPolarHBondContact O-CD2 3.27Å; F339-F365 HydrophobicContact CB-CB 3.88Å; F339-F365 HydrophobicContact CD2-CB 4.48Å; T342-F365 WeakPolarHBondContact OG1-CE2 3.33Å; L361-F365 HydrophobicContact CB-CD2 4.27Å; L361-F365 HydrophobicContact CB-CE2 4.02Å; L361-F365 HydrophobicContact CD2-CE1 4.5Å; L361-F365 HydrophobicContact CD2-CE2 4.24Å; L361-F365 HydrophobicContact CD2-CZ 3.93Å; L361-F365 VanDerWaalsContact O-CB 3.32Å; L361-F365 WeakPolarHBondContact O-CB 3.3Å; L361-F365 WeakPolarHBondContact O-CD2 3.44Å; L361-F365 WeakPolarHBondContact O-CG 3.31Å; L361-F365 PolarHBondContact O-N 2.88Å; L362-F365 PolarHBondContact O-N 2.82Å; F365-W367 VanDerWaalsContact C-N 3.31Å; F365-W367 PolarHBondContact O-N 3.19Å; F365-I368 HydrophobicContact CD1-CD1 3.89Å; F365-I368 HydrophobicContact CE1-CD1 4.39Å; F365-I368 PolarHBondContact O-N 3.36Å; F365-G369 PolarHBondContact O-N 3Å
366	V	95.1	Very high	93.9	Very high	18 Å²	18	39.6 Å²	39.6	11%	0.109	23%	0.225	C	C	.	.	H	α-helix	trans	-62	-40.3	172.5	71.5	0	0	0	0	111.2	F339 L362 N363 V364 G369 Y370	F339-V366 HydrophobicContact CD2-CB 4.01Å; F339-V366 HydrophobicContact CE2-CB 4.01Å; F339-V366 HydrophobicContact CE2-CG2 4.31Å; L362-V366 WeakPolarHBondContact O-CB 3.42Å; L362-V366 WeakPolarHBondContact O-CG1 3.38Å; L362-V366 PolarHBondContact O-N 3.47Å; N363-V366 WeakPolarHBondContact O-CG1 3.36Å; V364-V366 VanDerWaalsContact C-N 3.33Å; V364-V366 PolarHBondContact O-N 3.04Å; V366-G369 CarbonylContact O-C 3.58Å; V366-G369 WeakPolarHBondContact O-CA 3.42Å; V366-G369 PolarHBondContact O-N 3.5Å; V366-Y370 HydrophobicContact CG2-CD2 4.46Å; V366-Y370 HydrophobicContact CG2-CE1 4.05Å; V366-Y370 HydrophobicContact CG2-CE2 3.87Å; V366-Y370 PolarHBondContact O-N 3.24Å
367	W	96.1	Very high	94.2	Very high	33 Å²	33	32.3 Å²	32.3	13%	0.125	19%	0.191	C	C	.	.	H	α-helix	trans	-71.4	-31.5	176	-78.4	100.4	0	0	0	113.2	T82 I86 M129 M133 I136 N363 V364 F365 G369 Y370 L371	T82-W367 VanDerWaalsContact CB-CZ3 3.49Å; T82-W367 HydrophobicContact CG2-CD2 3.48Å; T82-W367 VanDerWaalsContact CG2-CD2 3.48Å; T82-W367 HydrophobicContact CG2-CE3 3.59Å; T82-W367 HydrophobicContact CG2-CG 4.26Å; T82-W367 HydrophobicContact CG2-CH2 3.49Å; T82-W367 VanDerWaalsContact CG2-CH2 3.49Å; T82-W367 HydrophobicContact CG2-CZ2 3.35Å; T82-W367 HydrophobicContact CG2-CZ3 3.58Å; I86-W367 HydrophobicContact CD1-CH2 4.38Å; M129-W367 HydrophobicContact CB-CH2 4.18Å; M129-W367 HydrophobicContact CB-CZ3 4.32Å; M133-W367 HydrophobicContact CB-CH2 4.35Å; M133-W367 HydrophobicContact CB-CZ2 4.38Å; I136-W367 HydrophobicContact CD1-CZ2 3.78Å; N363-W367 VanDerWaalsContact O-CD1 3.29Å; V364-W367 PolarHBondContact O-N 3.2Å; V364-W367 VanDerWaalsContact O-N 3.17Å; F365-W367 VanDerWaalsContact C-N 3.31Å; F365-W367 PolarHBondContact O-N 3.19Å; W367-G369 VanDerWaalsContact C-N 3.32Å; W367-Y370 HydrophobicContact CD2-CD2 4.02Å; W367-Y370 AromaticContact CE3-CD2 3.89Å; W367-Y370 HydrophobicContact CE3-CD2 3.89Å; W367-Y370 HydrophobicContact CH2-CD2 4.47Å; W367-Y370 HydrophobicContact CZ3-CD2 4.14Å; W367-Y370 PolarHBondContact O-N 3.43Å; W367-L371 WeakPolarHBondContact O-CB 3.35Å; W367-L371 PolarHBondContact O-N 3.41Å
368	I	96.6	Very high	94.3	Very high	61 Å²	61	33 Å²	33	31%	0.313	19%	0.192	S	C	.	.	H	α-helix	trans	-63.4	-42.1	169	-61.3	-178.4	0	0	0	110.1	M335 V364 F365 L371 S372	M335-I368 HydrophobicContact CB-CG2 4.1Å; M335-I368 HydrophobicContact CG-CG2 4.18Å; V364-I368 HydrophobicContact CG1-CD1 4.22Å; V364-I368 PolarHBondContact O-N 3.46Å; V364-I368 VanDerWaalsContact O-N 3.15Å; F365-I368 HydrophobicContact CD1-CD1 3.89Å; F365-I368 HydrophobicContact CE1-CD1 4.39Å; F365-I368 PolarHBondContact O-N 3.36Å; I368-L371 WeakPolarHBondContact O-CB 3.23Å; I368-L371 PolarHBondContact O-N 3.22Å; I368-S372 PolarHBondContact O-N 3.39Å
369	G	95.9	Very high	94.3	Very high	0 Å²	0	32.5 Å²	32.5	0%	0	19%	0.19	C	C	.	.	H	α-helix	trans	-58.4	-49.6	172.2	0	0	0	0	0	111.9	W336 F365 V366 W367 L371 S372	W336-G369 PolarHBondContact NE1-O 3.18Å; F365-G369 PolarHBondContact O-N 3Å; V366-G369 CarbonylContact O-C 3.58Å; V366-G369 WeakPolarHBondContact O-CA 3.42Å; V366-G369 PolarHBondContact O-N 3.5Å; W367-G369 VanDerWaalsContact C-N 3.32Å; G369-L371 VanDerWaalsContact C-N 3.3Å; G369-L371 PolarHBondContact O-N 3.03Å; G369-S372 WeakPolarHBondContact O-CB 3.47Å; G369-S372 PolarHBondContact O-N 3.17Å; G369-S372 PolarHBondContact O-OG 3.11Å
370	Y	96.7	Very high	94.3	Very high	1 Å²	1	31.7 Å²	31.7	0%	0.004	18%	0.178	C	C	.	.	H	α-helix	trans	-60.1	-36.1	176.2	-69.7	-16.7	0	0	0	113.3	L124 V128 M129 D156 W336 V366 W367 S372 S373	L124-Y370 HydrophobicContact CD1-CE1 4.2Å; L124-Y370 HydrophobicContact CD2-CD1 4.05Å; L124-Y370 HydrophobicContact CD2-CE1 4.47Å; L124-Y370 HydrophobicContact CG-CD1 4.49Å; V128-Y370 HydrophobicContact CG1-CE1 4.38Å; V128-Y370 WeakPolarHBondContact CG1-OH 3.48Å; M129-Y370 HydrophobicContact CE-CD1 4.33Å; M129-Y370 HydrophobicContact CE-CG 4.01Å; M129-Y370 WeakPolarHBondContact CE-O 3.34Å; M129-Y370 HydrophobicContact CG-CD2 3.93Å; M129-Y370 HydrophobicContact CG-CE2 4.36Å; M129-Y370 HydrophobicContact CG-CG 4.06Å; M129-Y370 HydrophobicContact SD-CG 4.43Å; D156-Y370 PolarHBondContact OD2-OH 2.81Å; W336-Y370 HydrophobicContact CH2-CD1 4.18Å; W336-Y370 HydrophobicContact CH2-CE1 4.29Å; W336-Y370 HydrophobicContact CZ2-CD1 4.47Å; V366-Y370 HydrophobicContact CG2-CD2 4.46Å; V366-Y370 HydrophobicContact CG2-CE1 4.05Å; V366-Y370 HydrophobicContact CG2-CE2 3.87Å; V366-Y370 PolarHBondContact O-N 3.24Å; W367-Y370 HydrophobicContact CD2-CD2 4.02Å; W367-Y370 AromaticContact CE3-CD2 3.89Å; W367-Y370 HydrophobicContact CE3-CD2 3.89Å; W367-Y370 HydrophobicContact CH2-CD2 4.47Å; W367-Y370 HydrophobicContact CZ3-CD2 4.14Å; W367-Y370 PolarHBondContact O-N 3.43Å; Y370-S372 PolarHBondContact O-N 3.49Å; Y370-S373 WeakPolarHBondContact O-CB 3.44Å; Y370-S373 PolarHBondContact O-N 3.21Å; Y370-S373 VanDerWaalsContact O-N 3.15Å
371	L	95.9	Very high	94.4	Very high	66 Å²	66	31.3 Å²	31.3	35%	0.346	17%	0.169	S	C	.	.	H	α-helix	trans	-60.4	-26.6	175.5	-175.7	63.7	0	0	0	112.3	V85 W367 I368 G369 S373 A374 V375	V85-L371 HydrophobicContact CG1-CD1 4.25Å; V85-L371 HydrophobicContact CG2-CD1 4.05Å; W367-L371 WeakPolarHBondContact O-CB 3.35Å; W367-L371 PolarHBondContact O-N 3.41Å; I368-L371 WeakPolarHBondContact O-CB 3.23Å; I368-L371 PolarHBondContact O-N 3.22Å; G369-L371 VanDerWaalsContact C-N 3.3Å; G369-L371 PolarHBondContact O-N 3.03Å; L371-S373 PolarHBondContact O-N 3.01Å; L371-A374 HydrophobicContact CD1-CB 4.25Å; L371-A374 WeakPolarHBondContact O-CB 3.44Å; L371-A374 PolarHBondContact O-N 2.99Å; L371-V375 HydrophobicContact CG-CG2 4.42Å; L371-V375 WeakPolarHBondContact O-CG2 3.46Å; L371-V375 PolarHBondContact O-N 3.09Å
372	S	94.8	Very high	94.2	Very high	5 Å²	5	33.1 Å²	33.1	4%	0.035	18%	0.178	C	C	.	.	H	α-helix	trans	-58.6	-35.8	176.5	75.6	0	0	0	0	113.1	M335 W336 I368 G369 Y370 A374 V375	M335-S372 WeakPolarHBondContact SD-CA 3.4Å; W336-S372 PolarHBondContact NE1-OG 3.15Å; I368-S372 PolarHBondContact O-N 3.39Å; G369-S372 WeakPolarHBondContact O-CB 3.47Å; G369-S372 PolarHBondContact O-N 3.17Å; G369-S372 PolarHBondContact O-OG 3.11Å; Y370-S372 PolarHBondContact O-N 3.49Å; S372-A374 VanDerWaalsContact C-N 3.3Å; S372-A374 PolarHBondContact O-N 3Å; S372-V375 PolarHBondContact O-N 3.47Å
373	S	95.4	Very high	93.9	Very high	3 Å²	3	36.6 Å²	36.6	2%	0.021	19%	0.192	C	C	.	.	H	α-helix	trans	-68	-27.7	177	-66.4	0	0	0	0	112.8	N93 D121 L124 Y370 L371	N93-S373 PolarHBondContact ND2-O 2.95Å; D121-S373 WeakPolarHBondContact OD1-CB 3.33Å; D121-S373 PolarHBondContact OD1-OG 3.33Å; L124-S373 WeakPolarHBondContact CD2-OG 3.01Å; Y370-S373 WeakPolarHBondContact O-CB 3.44Å; Y370-S373 PolarHBondContact O-N 3.21Å; Y370-S373 VanDerWaalsContact O-N 3.15Å; L371-S373 PolarHBondContact O-N 3.01Å
374	A	95.4	Very high	93.7	Very high	14 Å²	14	36.5 Å²	36.5	12%	0.116	19%	0.192	C	C	.	.	H	α-helix	trans	-77.9	-26.6	174.8	0	0	0	0	0	112.9	L88 T89 L371 S372	L88-A374 HydrophobicContact CB-CB 4.4Å; T89-A374 WeakPolarHBondContact OG1-CB 3.45Å; L371-A374 HydrophobicContact CD1-CB 4.25Å; L371-A374 WeakPolarHBondContact O-CB 3.44Å; L371-A374 PolarHBondContact O-N 2.99Å; S372-A374 VanDerWaalsContact C-N 3.3Å; S372-A374 PolarHBondContact O-N 3Å
375	V	95.3	Very high	93.5	Very high	24 Å²	24	40.1 Å²	40.1	15%	0.145	20%	0.2	C	C	.	.	H	α-helix	trans	-77	-26.9	-173.6	169.8	0	0	0	0	112.1	L331 M335 L371 S372 L378 V379	L331-V375 HydrophobicContact CD1-CG1 3.85Å; M335-V375 HydrophobicContact CE-CG2 3.99Å; M335-V375 HydrophobicContact SD-CG2 4.35Å; L371-V375 HydrophobicContact CG-CG2 4.42Å; L371-V375 WeakPolarHBondContact O-CG2 3.46Å; L371-V375 PolarHBondContact O-N 3.09Å; S372-V375 PolarHBondContact O-N 3.47Å; V375-L378 WeakPolarHBondContact O-CB 3.39Å; V375-L378 PolarHBondContact O-N 2.9Å; V375-V379 HydrophobicContact CG1-CG2 3.88Å; V375-V379 WeakPolarHBondContact O-CG2 3.41Å; V375-V379 PolarHBondContact O-N 2.9Å
376	N	92.5	Very high	93.2	Very high	10 Å²	10	40.5 Å²	40.5	5%	0.053	21%	0.206	C	C	.	.	H	α-helix	trans	-52.5	-56.2	-178.5	-74.7	-26.8	0	0	0	113.5	D121 L378 V379 Y380	D121-N376 PolarHBondContact OD2-ND2 3.28Å; N376-L378 VanDerWaalsContact C-N 3.27Å; N376-L378 PolarHBondContact O-N 3.27Å; N376-V379 PolarHBondContact O-N 3.4Å; N376-V379 VanDerWaalsContact O-N 3.16Å; N376-Y380 HydrophobicContact CB-CE2 4.31Å; N376-Y380 WeakPolarHBondContact O-CD1 3.36Å; N376-Y380 WeakPolarHBondContact O-CD2 3.5Å; N376-Y380 PolarHBondContact O-N 3.18Å; N376-Y380 VanDerWaalsContact O-N 3.1Å
377	P	94.8	Very high	93	Very high	7 Å²	7	39.7 Å²	39.7	5%	0.045	20%	0.201	C	C	.	.	H	α-helix	trans	-54.6	-38.9	174.2	-25.2	31.1	0	0	0	114	G92 V96 Y380 T381 F391	G92-P377 WeakPolarHBondContact O-CG 3.32Å; V96-P377 HydrophobicContact CG2-CB 3.95Å; V96-P377 HydrophobicContact CG2-CG 3.84Å; P377-Y380 PolarHBondContact O-N 2.81Å; P377-T381 WeakPolarHBondContact O-CG2 3.2Å; P377-T381 PolarHBondContact O-N 3.2Å; P377-T381 PolarHBondContact O-OG1 3.42Å; P377-F391 HydrophobicContact CB-CE2 4.16Å
378	L	93.7	Very high	92.9	Very high	99 Å²	99	44.3 Å²	44.3	52%	0.518	22%	0.219	S	C	.	.	H	α-helix	trans	-63.1	-45.7	178.3	-178.5	64.5	0	0	0	110.7	V375 N376 Y380 T381 L382	V375-L378 WeakPolarHBondContact O-CB 3.39Å; V375-L378 PolarHBondContact O-N 2.9Å; N376-L378 VanDerWaalsContact C-N 3.27Å; N376-L378 PolarHBondContact O-N 3.27Å; L378-Y380 VanDerWaalsContact C-N 3.3Å; L378-Y380 PolarHBondContact O-N 3.29Å; L378-T381 PolarHBondContact O-N 3.34Å; L378-T381 PolarHBondContact O-OG1 3.31Å; L378-L382 HydrophobicContact CD1-CD1 4.41Å; L378-L382 HydrophobicContact CD1-CG 4.42Å; L378-L382 HydrophobicContact CG-CD1 4.13Å; L378-L382 WeakPolarHBondContact O-CG 3.43Å; L378-L382 PolarHBondContact O-N 3.15Å
379	V	92	Very high	92.7	Very high	5 Å²	5	44.8 Å²	44.8	3%	0.03	23%	0.227	C	C	.	.	H	α-helix	trans	-59.9	-42.7	176.3	-179.3	0	0	0	0	110.8	V324 I327 V328 L331 V375 N376 T381 L382 F383	V324-V379 HydrophobicContact CG1-CG1 4.08Å; I327-V379 HydrophobicContact CG2-CG1 4.42Å; V328-V379 HydrophobicContact CG2-CB 4.12Å; V328-V379 HydrophobicContact CG2-CG1 3.53Å; L331-V379 HydrophobicContact CD1-CG2 3.79Å; V375-V379 HydrophobicContact CG1-CG2 3.88Å; V375-V379 WeakPolarHBondContact O-CG2 3.41Å; V375-V379 PolarHBondContact O-N 2.9Å; N376-V379 PolarHBondContact O-N 3.4Å; N376-V379 VanDerWaalsContact O-N 3.16Å; V379-T381 VanDerWaalsContact C-N 3.35Å; V379-T381 PolarHBondContact O-N 2.91Å; V379-L382 PolarHBondContact O-N 3.31Å; V379-F383 HydrophobicContact CG1-CD2 3.77Å; V379-F383 HydrophobicContact CG1-CE2 4.08Å; V379-F383 VanDerWaalsContact O-CD2 3.3Å; V379-F383 WeakPolarHBondContact O-CD2 3.45Å; V379-F383 PolarHBondContact O-N 3.2Å; V379-F383 VanDerWaalsContact O-N 3.16Å
380	Y	91.2	Very high	92.6	Very high	10 Å²	10	44.8 Å²	44.8	4%	0.039	23%	0.227	C	C	.	.	H	α-helix	trans	-63.9	-39.2	178.7	-53.7	-23.6	0	0	0	112.3	V96 L114 V328 N376 P377 L378 N384	V96-Y380 HydrophobicContact CG1-CD2 4.33Å; V96-Y380 HydrophobicContact CG1-CE2 4.19Å; V96-Y380 HydrophobicContact CG2-CD2 3.8Å; V96-Y380 HydrophobicContact CG2-CE2 4.06Å; L114-Y380 HydrophobicContact CD1-CE1 4.48Å; L114-Y380 HydrophobicContact CD2-CE1 4.25Å; L114-Y380 WeakPolarHBondContact CD2-OH 3.21Å; V328-Y380 HydrophobicContact CG2-CE1 4.12Å; N376-Y380 HydrophobicContact CB-CE2 4.31Å; N376-Y380 WeakPolarHBondContact O-CD1 3.36Å; N376-Y380 WeakPolarHBondContact O-CD2 3.5Å; N376-Y380 PolarHBondContact O-N 3.18Å; N376-Y380 VanDerWaalsContact O-N 3.1Å; P377-Y380 PolarHBondContact O-N 2.81Å; L378-Y380 VanDerWaalsContact C-N 3.3Å; L378-Y380 PolarHBondContact O-N 3.29Å; Y380-N384 WeakPolarHBondContact O-CA 3.26Å; Y380-N384 VanDerWaalsContact O-CB 3.26Å; Y380-N384 WeakPolarHBondContact O-CB 3.39Å; Y380-N384 PolarHBondContact O-N 3.4Å
381	T	92.3	Very high	92.5	Very high	27 Å²	27	45.2 Å²	45.2	17%	0.166	23%	0.229	C	C	.	.	H	α-helix	trans	-67.9	-37.9	176.5	59.7	0	0	0	0	113.4	P377 L378 V379 R388 F391	P377-T381 WeakPolarHBondContact O-CG2 3.2Å; P377-T381 PolarHBondContact O-N 3.2Å; P377-T381 PolarHBondContact O-OG1 3.42Å; L378-T381 PolarHBondContact O-N 3.34Å; L378-T381 PolarHBondContact O-OG1 3.31Å; V379-T381 VanDerWaalsContact C-N 3.35Å; V379-T381 PolarHBondContact O-N 2.91Å; T381-R388 WeakPolarHBondContact O-CB 3.33Å; T381-R388 WeakPolarHBondContact O-CD 3.47Å; T381-F391 HydrophobicContact CG2-CB 4.41Å; T381-F391 HydrophobicContact CG2-CD2 3.1Å; T381-F391 HydrophobicContact CG2-CE2 3.42Å; T381-F391 VanDerWaalsContact CG2-CE2 3.42Å; T381-F391 HydrophobicContact CG2-CG 3.98Å
382	L	90.1	Very high	92.4	Very high	104 Å²	104	45 Å²	45	55%	0.545	23%	0.233	S	C	.	.	H	α-helix	trans	-67.6	-41.4	-178.9	-70.7	174.5	0	0	0	111.7	L378 V379	L378-L382 HydrophobicContact CD1-CD1 4.41Å; L378-L382 HydrophobicContact CD1-CG 4.42Å; L378-L382 HydrophobicContact CG-CD1 4.13Å; L378-L382 WeakPolarHBondContact O-CG 3.43Å; L378-L382 PolarHBondContact O-N 3.15Å; V379-L382 PolarHBondContact O-N 3.31Å
383	F	86.4	Confident	92.3	Very high	102 Å²	102	46.9 Å²	46.9	45%	0.447	24%	0.24	S	C	.	.	H	α-helix	trans	-108.5	-9.6	-170	-59	-76.4	0	0	0	115.7	V324 I327 V379	V324-F383 HydrophobicContact CB-CB 4.2Å; V324-F383 HydrophobicContact CG1-CB 3.84Å; V324-F383 HydrophobicContact CG1-CD2 4.25Å; V324-F383 HydrophobicContact CG1-CG 4.31Å; V324-F383 HydrophobicContact CG2-CB 3.23Å; V324-F383 HydrophobicContact CG2-CD1 4.24Å; V324-F383 HydrophobicContact CG2-CD2 4.39Å; V324-F383 HydrophobicContact CG2-CG 3.74Å; I327-F383 HydrophobicContact CD1-CE1 4.04Å; I327-F383 HydrophobicContact CD1-CE2 3.86Å; I327-F383 HydrophobicContact CD1-CZ 3.54Å; I327-F383 HydrophobicContact CG2-CE2 4.41Å; V379-F383 HydrophobicContact CG1-CD2 3.77Å; V379-F383 HydrophobicContact CG1-CE2 4.08Å; V379-F383 VanDerWaalsContact O-CD2 3.3Å; V379-F383 WeakPolarHBondContact O-CD2 3.45Å; V379-F383 PolarHBondContact O-N 3.2Å; V379-F383 VanDerWaalsContact O-N 3.16Å
384	N	87.9	Confident	92.3	Very high	50 Å²	50	47.2 Å²	47.2	27%	0.267	24%	0.24	S	C	.	.			trans	-121.8	110	177.8	-169.8	-34.8	0	0	0	112	Y380 T386 Y387 R388	Y380-N384 WeakPolarHBondContact O-CA 3.26Å; Y380-N384 VanDerWaalsContact O-CB 3.26Å; Y380-N384 WeakPolarHBondContact O-CB 3.39Å; Y380-N384 PolarHBondContact O-N 3.4Å; N384-T386 PolarHBondContact O-N 3.24Å; N384-T386 WeakPolarHBondContact OD1-CB 3.15Å; N384-T386 PolarHBondContact OD1-N 3.45Å; N384-Y387 HydrophobicContact CB-CD2 3.79Å; N384-Y387 WeakPolarHBondContact ND2-CD2 3.47Å; N384-Y387 PolarHBondContact O-N 3Å; N384-Y387 PolarHBondContact OD1-N 3.47Å; N384-R388 PolarHBondContact O-N 2.7Å
385	K	88.5	Confident	92.2	Very high	162 Å²	162	52.5 Å²	52.5	70%	0.704	27%	0.265	S	S	*	.	H	α-helix	trans	-58.9	-32.9	-179.3	-65.3	-174.9	-179.1	-176.8	0	113.1	S389	K385-S389 WeakPolarHBondContact O-CB 3.21Å; K385-S389 PolarHBondContact O-N 3.06Å
386	T	89.7	Confident	92.2	Very high	49 Å²	49	56.1 Å²	56.1	30%	0.301	28%	0.281	S	S	.	.	H	α-helix	trans	-70	-47.7	179.8	-50.7	0	0	0	0	110.4	K105 L106 N384 R388 S389 A390	K105-T386 HydrophobicContact CB-CG2 4.35Å; L106-T386 HydrophobicContact CD1-CG2 4.09Å; L106-T386 HydrophobicContact CD2-CG2 3.84Å; L106-T386 HydrophobicContact CG-CG2 3.8Å; N384-T386 PolarHBondContact O-N 3.24Å; N384-T386 WeakPolarHBondContact OD1-CB 3.15Å; N384-T386 PolarHBondContact OD1-N 3.45Å; T386-R388 PolarHBondContact O-N 3.48Å; T386-S389 PolarHBondContact O-N 3.46Å; T386-A390 WeakPolarHBondContact O-CB 3.31Å; T386-A390 PolarHBondContact O-N 3.47Å
387	Y	92.2	Very high	92.3	Very high	2 Å²	2	59.8 Å²	59.8	1%	0.008	31%	0.306	C	S	.	.	H	α-helix	trans	-59.8	-46.5	173.2	-83.1	-74	0	0	0	111.4	V96 A99 V100 L106 N111 N384 S389 A390 F391	V96-Y387 HydrophobicContact CG1-CE1 4.31Å; A99-Y387 HydrophobicContact CB-CD1 3.73Å; A99-Y387 HydrophobicContact CB-CE1 3.8Å; V100-Y387 HydrophobicContact CG2-CE1 4.1Å; V100-Y387 WeakPolarHBondContact CG2-OH 3.21Å; L106-Y387 HydrophobicContact CD1-CD1 3.98Å; L106-Y387 HydrophobicContact CD1-CD2 4.34Å; L106-Y387 HydrophobicContact CD1-CE1 3.84Å; L106-Y387 HydrophobicContact CD1-CE2 4.2Å; L106-Y387 HydrophobicContact CD1-CG 4.23Å; L106-Y387 HydrophobicContact CD2-CD2 4.27Å; L106-Y387 HydrophobicContact CD2-CE2 3.98Å; N111-Y387 PolarHBondContact OD1-OH 2.9Å; N111-Y387 VanDerWaalsContact OD1-OH 3.09Å; N384-Y387 HydrophobicContact CB-CD2 3.79Å; N384-Y387 WeakPolarHBondContact ND2-CD2 3.47Å; N384-Y387 PolarHBondContact O-N 3Å; N384-Y387 PolarHBondContact OD1-N 3.47Å; Y387-S389 VanDerWaalsContact C-N 3.35Å; Y387-S389 PolarHBondContact O-N 3.47Å; Y387-A390 PolarHBondContact O-N 3.15Å; Y387-F391 AromaticContact CD1-CE1 3.75Å; Y387-F391 HydrophobicContact CD1-CE1 3.75Å; Y387-F391 HydrophobicContact CD1-CZ 4.03Å; Y387-F391 WeakPolarHBondContact O-CB 3.31Å; Y387-F391 VanDerWaalsContact O-CD1 3.28Å; Y387-F391 WeakPolarHBondContact O-CD1 3.49Å; Y387-F391 WeakPolarHBondContact O-CG 3.47Å; Y387-F391 PolarHBondContact O-N 3.23Å
388	R	94	Very high	92.1	Very high	129 Å²	129	66.5 Å²	66.5	49%	0.487	33%	0.331	S	S	.	.	H	α-helix	trans	-58	-45.6	178.7	-171	169.6	65.9	-159	10	112.9	T381 N384 T386 S392	T381-R388 WeakPolarHBondContact O-CB 3.33Å; T381-R388 WeakPolarHBondContact O-CD 3.47Å; N384-R388 PolarHBondContact O-N 2.7Å; T386-R388 PolarHBondContact O-N 3.48Å; R388-S392 WeakPolarHBondContact O-CB 3.37Å; R388-S392 PolarHBondContact O-N 3.27Å; R388-S392 VanDerWaalsContact O-N 3.08Å
389	S	92.2	Very high	91.7	Very high	71 Å²	71	68 Å²	68	50%	0.497	33%	0.33	S	S	.	.	H	α-helix	trans	-66.4	-39.9	177.7	-170.1	0	0	0	0	111.8	K385 T386 Y387 R393	K385-S389 WeakPolarHBondContact O-CB 3.21Å; K385-S389 PolarHBondContact O-N 3.06Å; T386-S389 PolarHBondContact O-N 3.46Å; Y387-S389 VanDerWaalsContact C-N 3.35Å; Y387-S389 PolarHBondContact O-N 3.47Å; S389-R393 WeakPolarHBondContact O-CG 3.44Å; S389-R393 PolarHBondContact O-N 3.39Å
390	A	93.1	Very high	91	Very high	0 Å²	0	76.8 Å²	76.8	0%	0	37%	0.368	C	S	.	.	H	α-helix	trans	-63.5	-49.4	177.2	0	0	0	0	0	111.1	A99 E103 T386 Y387 S392 R393 Y394	A99-A390 HydrophobicContact CB-CB 4.17Å; E103-A390 HydrophobicContact CG-CB 3.99Å; E103-A390 VanDerWaalsContact OE1-CB 3.27Å; E103-A390 WeakPolarHBondContact OE1-CB 3.34Å; T386-A390 WeakPolarHBondContact O-CB 3.31Å; T386-A390 PolarHBondContact O-N 3.47Å; Y387-A390 PolarHBondContact O-N 3.15Å; A390-S392 PolarHBondContact O-N 3.07Å; A390-R393 WeakPolarHBondContact O-CB 3.25Å; A390-R393 PolarHBondContact O-N 2.69Å; A390-R393 VanDerWaalsContact O-N 3.1Å; A390-Y394 HydrophobicContact CB-CE2 3.87Å; A390-Y394 WeakPolarHBondContact O-CD2 3.33Å; A390-Y394 PolarHBondContact O-N 2.77Å
391	F	94.9	Very high	89.9	Confident	11 Å²	11	82.5 Å²	82.5	5%	0.048	40%	0.395	C	S	.	.	H	α-helix	trans	-63	-44.1	-177.8	-74.2	19.4	0	0	0	111.7	L95 V96 A99 P377 T381 Y387 R393 Y394 I395	L95-F391 VanDerWaalsContact C-CE1 3.44Å; L95-F391 HydrophobicContact CB-CD1 4Å; L95-F391 HydrophobicContact CB-CD2 4.09Å; L95-F391 HydrophobicContact CB-CE1 3.79Å; L95-F391 HydrophobicContact CB-CE2 3.92Å; L95-F391 HydrophobicContact CB-CG 4.17Å; L95-F391 HydrophobicContact CB-CZ 3.77Å; L95-F391 HydrophobicContact CD1-CD2 4.12Å; L95-F391 HydrophobicContact CD1-CG 4.43Å; L95-F391 VanDerWaalsContact O-CE1 3.22Å; L95-F391 WeakPolarHBondContact O-CE1 3.28Å; V96-F391 HydrophobicContact CB-CZ 4.46Å; V96-F391 HydrophobicContact CG2-CZ 3.76Å; A99-F391 HydrophobicContact CB-CD1 4.22Å; A99-F391 HydrophobicContact CB-CE1 3.71Å; P377-F391 HydrophobicContact CB-CE2 4.16Å; T381-F391 HydrophobicContact CG2-CB 4.41Å; T381-F391 HydrophobicContact CG2-CD2 3.1Å; T381-F391 HydrophobicContact CG2-CE2 3.42Å; T381-F391 VanDerWaalsContact CG2-CE2 3.42Å; T381-F391 HydrophobicContact CG2-CG 3.98Å; Y387-F391 AromaticContact CD1-CE1 3.75Å; Y387-F391 HydrophobicContact CD1-CE1 3.75Å; Y387-F391 HydrophobicContact CD1-CZ 4.03Å; Y387-F391 WeakPolarHBondContact O-CB 3.31Å; Y387-F391 VanDerWaalsContact O-CD1 3.28Å; Y387-F391 WeakPolarHBondContact O-CD1 3.49Å; Y387-F391 WeakPolarHBondContact O-CG 3.47Å; Y387-F391 PolarHBondContact O-N 3.23Å; F391-R393 PolarHBondContact O-N 3.22Å; F391-Y394 PolarHBondContact O-N 3.37Å; F391-Y394 VanDerWaalsContact O-N 3.15Å; F391-I395 VanDerWaalsContact O-CG1 3.29Å; F391-I395 WeakPolarHBondContact O-CG1 3.42Å; F391-I395 PolarHBondContact O-N 3.24Å
392	S	93.8	Very high	88.4	Confident	61 Å²	61	89.2 Å²	89.2	43%	0.427	43%	0.425	S	S	.	.	H	α-helix	trans	-58.6	-37.5	175.5	177.5	0	0	0	0	112.2	R388 A390 Q396	R388-S392 WeakPolarHBondContact O-CB 3.37Å; R388-S392 PolarHBondContact O-N 3.27Å; R388-S392 VanDerWaalsContact O-N 3.08Å; A390-S392 PolarHBondContact O-N 3.07Å; S392-Q396 VanDerWaalsContact O-CG 3.3Å; S392-Q396 WeakPolarHBondContact O-CG 3.48Å; S392-Q396 PolarHBondContact O-N 3.33Å
393	R	94	Very high	86.6	Confident	44 Å²	44	93.4 Å²	93.4	17%	0.166	44%	0.439	C	S	.	.	H	α-helix	trans	-69.3	-42.7	174.6	-73.4	-166.3	-56.7	147.4	-8.6	112.5	E103 S389 A390 F391 Q396 C397 R398 K400	E103-R393 IonicContact OE1-CZ 2.64Å; E103-R393 IonicContact OE1-NH2 2.58Å; E103-R393 PolarHBondContact OE1-NH2 3.37Å; E103-R393 IonicContact OE2-NH2 3.52Å; S389-R393 WeakPolarHBondContact O-CG 3.44Å; S389-R393 PolarHBondContact O-N 3.39Å; A390-R393 WeakPolarHBondContact O-CB 3.25Å; A390-R393 PolarHBondContact O-N 2.69Å; A390-R393 VanDerWaalsContact O-N 3.1Å; F391-R393 PolarHBondContact O-N 3.22Å; R393-Q396 CarbonylContact O-C 3.44Å; R393-Q396 PolarHBondContact O-N 3.21Å; R393-C397 PolarHBondContact O-N 3.05Å; R393-C397 VanDerWaalsContact O-N 3.15Å; R393-R398 HydrophobicContact CB-CB 4.32Å; R393-R398 PolarHBondContact O-N 3.29Å; R393-K400 PolarHBondContact NH1-O 2.99Å
394	Y	94.6	Very high	85.1	Confident	10 Å²	10	96.8 Å²	96.8	4%	0.039	45%	0.453	C	S	.	.	H	α-helix	trans	-67.6	-39.2	-178.2	-58.6	-25.6	0	0	0	112.6	L95 M98 A99 L102 E103 A390 F391 Q396 C397 Y399	L95-Y394 HydrophobicContact CD2-CD2 4.25Å; M98-Y394 HydrophobicContact CB-CD2 4.23Å; M98-Y394 HydrophobicContact CB-CE2 4.01Å; M98-Y394 HydrophobicContact CE-CD2 4.22Å; M98-Y394 HydrophobicContact CE-CG 4.42Å; A99-Y394 HydrophobicContact CB-CE2 4.04Å; L102-Y394 WeakPolarHBondContact CB-OH 3.48Å; L102-Y394 HydrophobicContact CD1-CE1 4.03Å; E103-Y394 PolarHBondContact OE1-OH 3.13Å; A390-Y394 HydrophobicContact CB-CE2 3.87Å; A390-Y394 WeakPolarHBondContact O-CD2 3.33Å; A390-Y394 PolarHBondContact O-N 2.77Å; F391-Y394 PolarHBondContact O-N 3.37Å; F391-Y394 VanDerWaalsContact O-N 3.15Å; Y394-Q396 PolarHBondContact O-N 3.44Å; Y394-C397 PolarHBondContact O-N 3.04Å; Y394-Y399 AromaticContact CD1-CD1 3.84Å; Y394-Y399 HydrophobicContact CD1-CD1 3.84Å; Y394-Y399 HydrophobicContact CD1-CE1 4.04Å; Y394-Y399 HydrophobicContact CE1-CD1 4.27Å
395	I	93.5	Very high	82.9	Confident	125 Å²	125	98.9 Å²	98.9	64%	0.641	47%	0.47	S	S	*	.	H	α-helix	trans	-62.9	-29.6	174.3	-65.6	165.2	0	0	0	111.2	F391 C397	F391-I395 VanDerWaalsContact O-CG1 3.29Å; F391-I395 WeakPolarHBondContact O-CG1 3.42Å; F391-I395 PolarHBondContact O-N 3.24Å; I395-C397 VanDerWaalsContact C-N 3.34Å
396	Q	94.9	Very high	81.1	Confident	100 Å²	100	99.9 Å²	99.9	47%	0.467	47%	0.474	S	S	.	.	T	Hydrogen-bonded Turn	trans	-90.5	7.1	174.9	-64.6	172.7	7.9	0	0	113.4	S392 R393 Y394 R398	S392-Q396 VanDerWaalsContact O-CG 3.3Å; S392-Q396 WeakPolarHBondContact O-CG 3.48Å; S392-Q396 PolarHBondContact O-N 3.33Å; R393-Q396 CarbonylContact O-C 3.44Å; R393-Q396 PolarHBondContact O-N 3.21Å; Y394-Q396 PolarHBondContact O-N 3.44Å; Q396-R398 HydrophobicContact CB-CG 4.04Å; Q396-R398 PolarHBondContact O-N 3.36Å
397	C	93.7	Very high	79.2	Confident	87 Å²	87	105.4 Å²	105.4	59%	0.588	50%	0.497	S	S	*	.	T	Hydrogen-bonded Turn	trans	55.6	29.1	-175.4	-58.4	0	0	0	0	114.4	R393 Y394 I395 Y399	R393-C397 PolarHBondContact O-N 3.05Å; R393-C397 VanDerWaalsContact O-N 3.15Å; Y394-C397 PolarHBondContact O-N 3.04Å; I395-C397 VanDerWaalsContact C-N 3.34Å; C397-Y399 HydrophobicContact CB-CE2 3.98Å; C397-Y399 WeakPolarHBondContact O-CD2 3.38Å; C397-Y399 WeakPolarHBondContact O-CE2 3.38Å; C397-Y399 PolarHBondContact O-N 2.77Å
398	R	90.9	Very high	77	Confident	148 Å²	148	111.8 Å²	111.8	56%	0.558	53%	0.53	S	S	*	.			trans	-97.2	74.9	-179.5	-64.4	-176.4	-175.8	-170.7	2.9	112	R393 Q396 K400	R393-R398 HydrophobicContact CB-CB 4.32Å; R393-R398 PolarHBondContact O-N 3.29Å; Q396-R398 HydrophobicContact CB-CG 4.04Å; Q396-R398 PolarHBondContact O-N 3.36Å; R398-K400 PolarHBondContact O-N 3.45Å
399	Y	85.6	Confident	74.7	Confident	130 Å²	130	111.1 Å²	111.1	51%	0.51	54%	0.535	S	S	.	.			trans	-78.4	-17.1	-175.3	-51.2	-75.4	0	0	0	114.9	Y394 C397	Y394-Y399 AromaticContact CD1-CD1 3.84Å; Y394-Y399 HydrophobicContact CD1-CD1 3.84Å; Y394-Y399 HydrophobicContact CD1-CE1 4.04Å; Y394-Y399 HydrophobicContact CE1-CD1 4.27Å; C397-Y399 HydrophobicContact CB-CE2 3.98Å; C397-Y399 WeakPolarHBondContact O-CD2 3.38Å; C397-Y399 WeakPolarHBondContact O-CE2 3.38Å; C397-Y399 PolarHBondContact O-N 2.77Å
400	K	77.5	Confident	72.5	Confident	190 Å²	190	113.4 Å²	113.4	83%	0.826	54%	0.541	S	S	*	.	S	Bend	trans	-78.1	130.5	178.7	-65.8	178	-178.5	176	0	109.8	R393 R398 E402	R393-K400 PolarHBondContact NH1-O 2.99Å; R398-K400 PolarHBondContact O-N 3.45Å; K400-E402 PolarHBondContact O-N 3.31Å
401	E	68.6	Low	70.4	Confident	130 Å²	130	118.6 Å²	118.6	61%	0.607	57%	0.573	S	S	*	*			trans	-64.9	120.1	166.5	-82.1	-174.4	141.8	0	0	108.3	K403	E401-K403 VanDerWaalsContact C-N 3.32Å; E401-K403 PolarHBondContact O-N 3.37Å
402	E	59.5	Low	68	Low	168 Å²	168	125.4 Å²	125.4	79%	0.785	61%	0.61	S	S	*	*			trans	-61.6	102.1	161.9	-74.9	-170.6	-177.8	0	0	106.9	K400 K404	K400-E402 PolarHBondContact O-N 3.31Å; E402-K404 PolarHBondContact O-N 3.19Å
403	K	53	Low	65.9	Low	193 Å²	193	127.9 Å²	127.9	84%	0.839	62%	0.622	S	S	*	*			trans	-56.8	106.7	165.6	-70.1	-176.5	-179.3	-179.5	0	105.3	E401 P405	E401-K403 VanDerWaalsContact C-N 3.32Å; E401-K403 PolarHBondContact O-N 3.37Å; K403-P405 WeakPolarHBondContact O-CD 3.42Å
404	K	54	Low	63.6	Low	172 Å²	172	130 Å²	130	75%	0.748	64%	0.636	S	S	*	*			trans	-49	122.4	167.9	-74.5	-170.5	177.6	-171.6	0	105.8	E402 F406	E402-K404 PolarHBondContact O-N 3.19Å; K404-F406 PolarHBondContact O-N 3.15Å; K404-F406 VanDerWaalsContact O-N 3.16Å
405	P	43.1	Very low	61.2	Low	95 Å²	95	134.1 Å²	134.1	62%	0.617	66%	0.664	S	S	*	*			trans	-54.4	131.1	-179.8	20.5	-30.4	0	0	0	107.3	K403 Q407 L408	K403-P405 WeakPolarHBondContact O-CD 3.42Å; P405-Q407 PolarHBondContact O-N 3.42Å; P405-L408 PolarHBondContact O-N 3.34Å
406	F	50.8	Low	58.9	Low	182 Å²	182	133.1 Å²	133.1	80%	0.798	67%	0.674	S	S	*	*	G	3₁₀ helix	trans	-49.7	-12.9	-178	-109.8	-91.6	0	0	0	113.8	K404 L408 I409	K404-F406 PolarHBondContact O-N 3.15Å; K404-F406 VanDerWaalsContact O-N 3.16Å; F406-L408 PolarHBondContact O-N 2.88Å; F406-I409 PolarHBondContact O-N 3.47Å
407	Q	48.7	Very low	56.5	Low	165 Å²	165	136.2 Å²	136.2	77%	0.771	69%	0.693	S	S	*	*	G	3₁₀ helix	trans	-64	-18.1	179	-61.9	-161.8	-17.6	0	0	115	P405	P405-Q407 PolarHBondContact O-N 3.42Å
408	L	46	Very low	54.1	Low	136 Å²	136	134 Å²	134	71%	0.712	68%	0.681	S	S	*	*	G	3₁₀ helix	trans	-90.4	-9.1	177.8	-140.9	88.5	0	0	0	114.5	P405 F406	P405-L408 PolarHBondContact O-N 3.34Å; F406-L408 PolarHBondContact O-N 2.88Å
409	I	45.8	Very low	51.8	Low	115 Å²	115	134.3 Å²	134.3	59%	0.59	68%	0.683	S	S	*	*	T	Hydrogen-bonded Turn	trans	-91.2	-26.2	-179.7	-65	175.1	0	0	0	111.2	F406 V411 T413	F406-I409 PolarHBondContact O-N 3.47Å; I409-V411 PolarHBondContact O-N 2.81Å; I409-T413 PolarHBondContact O-OG1 2.79Å
410	L	46.1	Very low	49.7	Very low	119 Å²	119	134.6 Å²	134.6	62%	0.623	69%	0.694	S	S	*	*	S	Bend	trans	-79.5	-14.7	-177.1	-139	82.8	0	0	0	114.4	I414	L410-I414 HydrophobicContact CD2-CD1 3.94Å; L410-I414 HydrophobicContact CG-CD1 3.98Å; L410-I414 WeakPolarHBondContact O-CD1 3.32Å; L410-I414 WeakPolarHBondContact O-CG1 3.17Å
411	V	49	Very low	48.1	Very low	110 Å²	110	129 Å²	129	67%	0.667	68%	0.678	S	S	*	*	S	Bend	trans	-82.6	-21.8	-173.9	-174.2	0	0	0	0	112.6	I409	I409-V411 PolarHBondContact O-N 2.81Å
412	N	45.1	Very low	47	Very low	154 Å²	154	125.6 Å²	125.6	82%	0.824	67%	0.669	S	S	*	*	S	Bend	trans	-104.2	6.9	-177.4	-84.4	3.1	0	0	0	114.7
413	T	49.2	Very low	46.4	Very low	112 Å²	112	122.7 Å²	122.7	69%	0.687	66%	0.655	S	S	*	*	S	Bend	trans	-122.3	-0.2	-178.2	-23.9	0	0	0	0	113.9	I409	I409-T413 PolarHBondContact O-OG1 2.79Å
414	I	45.9	Very low	46.1	Very low	90 Å²	90	119.1 Å²	119.1	46%	0.462	65%	0.645	S	S	.	*	S	Bend	trans	-101.3	116.2	178.5	-59.7	177.3	0	0	0	108.7	L410 A418	L410-I414 HydrophobicContact CD2-CD1 3.94Å; L410-I414 HydrophobicContact CG-CD1 3.98Å; L410-I414 WeakPolarHBondContact O-CD1 3.32Å; L410-I414 WeakPolarHBondContact O-CG1 3.17Å; I414-A418 HydrophobicContact CG2-CB 3.66Å
415	P	43.3	Very low	45.6	Very low	96 Å²	96	117.4 Å²	117.4	62%	0.623	64%	0.64	S	S	*	*			trans	-56.5	141.2	168.5	-18.3	29.7	0	0	0	109.6	L417 A418	P415-L417 PolarHBondContact O-N 3.01Å; P415-A418 PolarHBondContact O-N 3Å; P415-A418 VanDerWaalsContact O-N 3.14Å
416	A	46.3	Very low	46	Very low	104 Å²	104	117.2 Å²	117.2	86%	0.86	63%	0.633	S	S	*	*	T	Hydrogen-bonded Turn	trans	-55.3	-1.1	-177.7	0	0	0	0	0	115.9
417	L	44.8	Very low	46.1	Very low	165 Å²	165	111.2 Å²	111.2	86%	0.864	62%	0.617	S	S	*	*	T	Hydrogen-bonded Turn	trans	-86.1	-16.3	177	-76.6	157.8	0	0	0	114.4	P415	P415-L417 PolarHBondContact O-N 3.01Å
418	A	44	Very low	46.1	Very low	40 Å²	40	109 Å²	109	33%	0.331	61%	0.607	S	S	.	*	S	Bend	trans	-94.7	2.3	180	0	0	0	0	0	114.4	I414 P415 N420 S421 S422	I414-A418 HydrophobicContact CG2-CB 3.66Å; P415-A418 PolarHBondContact O-N 3Å; P415-A418 VanDerWaalsContact O-N 3.14Å; A418-N420 VanDerWaalsContact C-N 3.32Å; A418-N420 PolarHBondContact O-N 3.21Å; A418-S421 PolarHBondContact O-OG 3.21Å; A418-S422 PolarHBondContact O-OG 3.43Å
419	Y	40.6	Very low	46.3	Very low	154 Å²	154	109.1 Å²	109.1	60%	0.604	61%	0.605	S	S	*	*	H	α-helix	trans	-71	-27.1	179	-169.8	-104.4	0	0	0	112.6	S422	Y419-S422 PolarHBondContact O-OG 2.86Å
420	N	41.9	Very low	46.7	Very low	137 Å²	137	110.3 Å²	110.3	73%	0.733	61%	0.606	S	S	*	*	H	α-helix	trans	-86.5	-24.2	-177.8	-72.6	-6.7	0	0	0	114	A418	A418-N420 VanDerWaalsContact C-N 3.32Å; A418-N420 PolarHBondContact O-N 3.21Å
421	S	45.2	Very low	46.8	Very low	72 Å²	72	107.4 Å²	107.4	50%	0.503	60%	0.596	S	S	.	*	H	α-helix	trans	-84.4	-31	178	63.7	0	0	0	0	113.1	A418 L424 Q425	A418-S421 PolarHBondContact O-OG 3.21Å; S421-L424 PolarHBondContact O-N 3.36Å; S421-Q425 PolarHBondContact O-N 2.88Å
422	S	45.1	Very low	46.7	Very low	58 Å²	58	107.6 Å²	107.6	41%	0.406	59%	0.592	S	S	.	*	H	α-helix	trans	-75.5	-28.4	-177.8	45.2	0	0	0	0	113.4	A418 Y419 Q425 L426	A418-S422 PolarHBondContact O-OG 3.43Å; Y419-S422 PolarHBondContact O-OG 2.86Å; S422-Q425 PolarHBondContact O-N 3.44Å; S422-L426 WeakPolarHBondContact O-CB 3.36Å; S422-L426 PolarHBondContact O-N 2.64Å
423	Q	47.4	Very low	47	Very low	108 Å²	108	108.2 Å²	108.2	51%	0.505	59%	0.588	S	S	.	*	H	α-helix	trans	-64.7	-38.1	170.8	-79.5	-76.3	11.1	0	0	112.3	L426 A427	Q423-L426 PolarHBondContact O-N 3.07Å; Q423-A427 VanDerWaalsContact O-CB 3.32Å; Q423-A427 WeakPolarHBondContact O-CB 3.34Å; Q423-A427 PolarHBondContact O-N 3.1Å
424	L	44.9	Very low	47.1	Very low	118 Å²	118	110 Å²	110	62%	0.618	59%	0.586	S	S	*	*	H	α-helix	trans	-68	-41.3	178.3	-164.3	70.4	0	0	0	111.4	S421 Q428	S421-L424 PolarHBondContact O-N 3.36Å; L424-Q428 WeakPolarHBondContact O-CB 3.38Å; L424-Q428 PolarHBondContact O-N 2.99Å
425	Q	45.4	Very low	47.3	Very low	136 Å²	136	110.7 Å²	110.7	64%	0.636	59%	0.587	S	S	*	*	H	α-helix	trans	-70.2	-35.5	176.2	-74	-172.5	-35.3	0	0	113	S421 S422 Q428 M429	S421-Q425 PolarHBondContact O-N 2.88Å; S422-Q425 PolarHBondContact O-N 3.44Å; Q425-Q428 PolarHBondContact O-N 2.9Å; Q425-M429 WeakPolarHBondContact O-CB 3.39Å; Q425-M429 PolarHBondContact O-N 2.81Å
426	L	49.8	Very low	47.6	Very low	90 Å²	90	109 Å²	109	47%	0.471	58%	0.581	S	S	.	*	H	α-helix	trans	-72.9	-33.4	177.3	-158.7	75.4	0	0	0	112	S422 Q423 K430	S422-L426 WeakPolarHBondContact O-CB 3.36Å; S422-L426 PolarHBondContact O-N 2.64Å; Q423-L426 PolarHBondContact O-N 3.07Å; L426-K430 WeakPolarHBondContact O-CB 3.22Å; L426-K430 WeakPolarHBondContact O-CG 3.09Å; L426-K430 PolarHBondContact O-N 2.96Å
427	A	54	Low	47.6	Very low	57 Å²	57	112 Å²	112	47%	0.471	58%	0.575	S	S	.	*	H	α-helix	trans	-67	-44.1	171.1	0	0	0	0	0	111.5	Q423 K430 S431	Q423-A427 VanDerWaalsContact O-CB 3.32Å; Q423-A427 WeakPolarHBondContact O-CB 3.34Å; Q423-A427 PolarHBondContact O-N 3.1Å; A427-K430 PolarHBondContact O-N 3.49Å; A427-S431 WeakPolarHBondContact O-CB 3.33Å; A427-S431 PolarHBondContact O-N 3.41Å
428	Q	48.7	Very low	47.8	Very low	118 Å²	118	109.3 Å²	109.3	55%	0.551	56%	0.559	S	S	*	*	H	α-helix	trans	-63	-41.6	173.8	-84.9	176.6	-38.6	0	0	112.6	L424 Q425 K430 S431 L432	L424-Q428 WeakPolarHBondContact O-CB 3.38Å; L424-Q428 PolarHBondContact O-N 2.99Å; Q425-Q428 PolarHBondContact O-N 2.9Å; Q428-K430 PolarHBondContact O-N 3.36Å; Q428-S431 WeakPolarHBondContact O-CB 3.46Å; Q428-S431 PolarHBondContact O-N 3.02Å; Q428-L432 WeakPolarHBondContact O-CB 3.38Å; Q428-L432 PolarHBondContact O-N 2.92Å
429	M	49.3	Very low	47.9	Very low	138 Å²	138	114.2 Å²	114.2	68%	0.68	58%	0.577	S	S	*	*	H	α-helix	trans	-65.1	-37.8	174.9	-102.8	-170.3	169.3	0	0	112.6	Q425 K433	Q425-M429 WeakPolarHBondContact O-CB 3.39Å; Q425-M429 PolarHBondContact O-N 2.81Å; M429-K433 VanDerWaalsContact O-CB 3.25Å; M429-K433 WeakPolarHBondContact O-CB 3.49Å; M429-K433 PolarHBondContact O-N 3.25Å
430	K	54	Low	48.2	Very low	141 Å²	141	110.1 Å²	110.1	61%	0.613	58%	0.575	S	S	*	*	H	α-helix	trans	-69.1	-35.6	174.7	-77.3	177.1	-178.6	178.1	0	111.8	L426 A427 Q428 K434	L426-K430 WeakPolarHBondContact O-CB 3.22Å; L426-K430 WeakPolarHBondContact O-CG 3.09Å; L426-K430 PolarHBondContact O-N 2.96Å; A427-K430 PolarHBondContact O-N 3.49Å; Q428-K430 PolarHBondContact O-N 3.36Å; K430-K434 VanDerWaalsContact O-CB 3.28Å; K430-K434 WeakPolarHBondContact O-CB 3.5Å; K430-K434 PolarHBondContact O-N 3.5Å
431	S	48.8	Very low	48.2	Very low	58 Å²	58	110.5 Å²	110.5	41%	0.406	57%	0.57	S	S	.	*	H	α-helix	trans	-61.6	-53.9	172.6	-172	0	0	0	0	111.2	A427 Q428 K433 K434 E435	A427-S431 WeakPolarHBondContact O-CB 3.33Å; A427-S431 PolarHBondContact O-N 3.41Å; Q428-S431 WeakPolarHBondContact O-CB 3.46Å; Q428-S431 PolarHBondContact O-N 3.02Å; S431-K433 VanDerWaalsContact C-N 3.31Å; S431-K433 PolarHBondContact O-N 2.87Å; S431-K434 CarbonylContact O-C 3.6Å; S431-K434 WeakPolarHBondContact O-CA 3.3Å; S431-K434 WeakPolarHBondContact O-CB 2.94Å; S431-K434 PolarHBondContact O-N 3.1Å; S431-E435 PolarHBondContact O-N 2.01Å
432	L	47.8	Very low	47.9	Very low	114 Å²	114	112 Å²	112	60%	0.597	57%	0.572	S	S	*	*	H	α-helix	trans	-60.2	-38.2	177.6	-92.2	151.3	0	0	0	112.6	Q428 K434 A436	Q428-L432 WeakPolarHBondContact O-CB 3.38Å; Q428-L432 PolarHBondContact O-N 2.92Å; L432-K434 VanDerWaalsContact C-N 3.32Å; L432-A436 VanDerWaalsContact O-CB 3.25Å; L432-A436 WeakPolarHBondContact O-CB 3.41Å; L432-A436 PolarHBondContact O-N 3.11Å
433	K	50	Low	47.6	Very low	166 Å²	166	118.3 Å²	118.3	72%	0.722	59%	0.589	S	S	*	*	H	α-helix	trans	-72.7	-26.6	176.6	-154.2	174.4	-169	177.8	0	112.3	M429 S431 K437	M429-K433 VanDerWaalsContact O-CB 3.25Å; M429-K433 WeakPolarHBondContact O-CB 3.49Å; M429-K433 PolarHBondContact O-N 3.25Å; S431-K433 VanDerWaalsContact C-N 3.31Å; S431-K433 PolarHBondContact O-N 2.87Å; K433-K437 VanDerWaalsContact O-CB 3.28Å; K433-K437 WeakPolarHBondContact O-CB 3.4Å; K433-K437 PolarHBondContact O-N 2.73Å
434	K	52.3	Low	47.1	Very low	151 Å²	151	116.6 Å²	116.6	66%	0.657	59%	0.588	S	S	*	*	H	α-helix	trans	-77.8	-39.7	174.5	-160.5	179.6	-176.6	-172.2	0	110.8	K430 S431 L432 K437 M438	K430-K434 VanDerWaalsContact O-CB 3.28Å; K430-K434 WeakPolarHBondContact O-CB 3.5Å; K430-K434 PolarHBondContact O-N 3.5Å; S431-K434 CarbonylContact O-C 3.6Å; S431-K434 WeakPolarHBondContact O-CA 3.3Å; S431-K434 WeakPolarHBondContact O-CB 2.94Å; S431-K434 PolarHBondContact O-N 3.1Å; L432-K434 VanDerWaalsContact C-N 3.32Å; K434-K437 PolarHBondContact O-N 3.21Å; K434-M438 PolarHBondContact O-N 3.35Å
435	E	49.6	Very low	46.8	Very low	103 Å²	103	118.3 Å²	118.3	48%	0.481	60%	0.595	S	S	.	*	H	α-helix	trans	-65.6	-45.1	172.8	-76.3	174.4	161.9	0	0	112	S431 K437 M438 M439	S431-E435 PolarHBondContact O-N 2.01Å; E435-K437 VanDerWaalsContact C-N 3.26Å; E435-K437 PolarHBondContact O-N 2.92Å; E435-M438 WeakPolarHBondContact O-CB 2.93Å; E435-M438 PolarHBondContact O-N 2.73Å; E435-M438 VanDerWaalsContact O-N 3.09Å; E435-M439 PolarHBondContact O-N 2.98Å
436	A	48.8	Very low	46.5	Very low	60 Å²	60	117.7 Å²	117.7	50%	0.496	60%	0.6	S	S	.	*	H	α-helix	trans	-62.8	-32.8	175.2	0	0	0	0	0	112.7	L432 A440	L432-A436 VanDerWaalsContact O-CB 3.25Å; L432-A436 WeakPolarHBondContact O-CB 3.41Å; L432-A436 PolarHBondContact O-N 3.11Å; A436-A440 WeakPolarHBondContact O-CB 3.34Å; A436-A440 PolarHBondContact O-N 3.3Å
437	K	46.7	Very low	45.9	Very low	168 Å²	168	118.4 Å²	118.4	73%	0.73	61%	0.609	S	S	*	*	H	α-helix	trans	-78.6	-21.7	176.5	-153	175.4	-170.6	-175.7	0	112.8	K433 K434 E435 K441	K433-K437 VanDerWaalsContact O-CB 3.28Å; K433-K437 WeakPolarHBondContact O-CB 3.4Å; K433-K437 PolarHBondContact O-N 2.73Å; K434-K437 PolarHBondContact O-N 3.21Å; E435-K437 VanDerWaalsContact C-N 3.26Å; E435-K437 PolarHBondContact O-N 2.92Å; K437-K441 PolarHBondContact O-N 3.16Å
438	M	50.3	Low	45.1	Very low	108 Å²	108	123.4 Å²	123.4	53%	0.532	63%	0.626	S	S	.	*	H	α-helix	trans	-77.5	-47.1	171.2	-132	178.7	-65.7	0	0	110.3	K434 E435 A440 K441 D442	K434-M438 PolarHBondContact O-N 3.35Å; E435-M438 WeakPolarHBondContact O-CB 2.93Å; E435-M438 PolarHBondContact O-N 2.73Å; E435-M438 VanDerWaalsContact O-N 3.09Å; M438-A440 VanDerWaalsContact C-N 3.32Å; M438-A440 PolarHBondContact O-N 3.19Å; M438-K441 WeakPolarHBondContact O-CB 3.45Å; M438-K441 PolarHBondContact O-N 3.47Å; M438-D442 PolarHBondContact O-N 2.94Å
439	M	45.4	Very low	44.4	Very low	144 Å²	144	120.6 Å²	120.6	71%	0.709	63%	0.628	S	S	*	*	H	α-helix	trans	-61.1	-36.9	175.1	-71.5	-162.8	-168.9	0	0	113.1	E435 K441 D442 Y443	E435-M439 PolarHBondContact O-N 2.98Å; M439-K441 VanDerWaalsContact C-N 3.26Å; M439-K441 PolarHBondContact O-N 2.81Å; M439-D442 PolarHBondContact O-N 3.04Å; M439-Y443 PolarHBondContact O-N 2.85Å; M439-Y443 VanDerWaalsContact O-N 3.14Å
440	A	46.3	Very low	43.6	Very low	67 Å²	67	121.8 Å²	121.8	55%	0.554	64%	0.636	S	S	*	*	H	α-helix	trans	-68.5	-24.8	174.5	0	0	0	0	0	113.2	A436 M438	A436-A440 WeakPolarHBondContact O-CB 3.34Å; A436-A440 PolarHBondContact O-N 3.3Å; M438-A440 VanDerWaalsContact C-N 3.32Å; M438-A440 PolarHBondContact O-N 3.19Å
441	K	41.5	Very low	42.4	Very low	145 Å²	145	126.3 Å²	126.3	63%	0.63	65%	0.649	S	S	*	*	H	α-helix	trans	-81.7	-36.7	177.8	-150.8	176.6	-175.7	-174.2	0	111.1	K437 M438 M439 S444 M445	K437-K441 PolarHBondContact O-N 3.16Å; M438-K441 WeakPolarHBondContact O-CB 3.45Å; M438-K441 PolarHBondContact O-N 3.47Å; M439-K441 VanDerWaalsContact C-N 3.26Å; M439-K441 PolarHBondContact O-N 2.81Å; K441-S444 PolarHBondContact O-N 3.34Å; K441-S444 PolarHBondContact O-OG 3.02Å; K441-M445 PolarHBondContact O-N 3.3Å
442	D	40.2	Very low	41.4	Very low	104 Å²	104	132.2 Å²	132.2	56%	0.556	67%	0.67	S	S	*	*	H	α-helix	trans	-68.2	-33	175.1	-68.2	-23.6	0	0	0	112.3	M438 M439 S444 M445	M438-D442 PolarHBondContact O-N 2.94Å; M439-D442 PolarHBondContact O-N 3.04Å; D442-S444 VanDerWaalsContact C-N 3.33Å; D442-S444 PolarHBondContact O-N 3.4Å; D442-M445 PolarHBondContact O-N 3.38Å
443	Y	37.6	Very low	40.5	Very low	191 Å²	191	135 Å²	135	75%	0.749	69%	0.685	S	S	*	*	H	α-helix	trans	-71.2	-26.2	172.8	-147.7	-95.1	0	0	0	113.1	M439 T447	M439-Y443 PolarHBondContact O-N 2.85Å; M439-Y443 VanDerWaalsContact O-N 3.14Å; Y443-T447 PolarHBondContact O-OG1 3.33Å
444	S	38.6	Very low	39.5	Very low	71 Å²	71	134.9 Å²	134.9	50%	0.497	69%	0.692	S	S	.	*	H	α-helix	trans	-80.7	-18.5	176.3	83.3	0	0	0	0	113.9	K441 D442	K441-S444 PolarHBondContact O-N 3.34Å; K441-S444 PolarHBondContact O-OG 3.02Å; D442-S444 VanDerWaalsContact C-N 3.33Å; D442-S444 PolarHBondContact O-N 3.4Å
445	M	37.4	Very low	38.3	Very low	155 Å²	155	130.4 Å²	130.4	76%	0.764	69%	0.688	S	S	*	*	H	α-helix	trans	-88.7	-10.7	176.4	-103.2	-168.9	-168.3	0	0	114.1	K441 D442	K441-M445 PolarHBondContact O-N 3.3Å; D442-M445 PolarHBondContact O-N 3.38Å
446	V	38.9	Very low	37.3	Very low	122 Å²	122	132.2 Å²	132.2	74%	0.739	71%	0.706	S	S	*	*	S	Bend	trans	-95.6	-8.4	175.4	179.7	0	0	0	0	112.6
447	T	37	Very low	36.2	Very low	106 Å²	106	133.5 Å²	133.5	65%	0.65	71%	0.712	S	S	*	*	S	Bend	trans	-106.2	33.6	-179.5	-36.9	0	0	0	0	112.9	Y443	Y443-T447 PolarHBondContact O-OG1 3.33Å
448	I	38	Very low	35.3	Very low	161 Å²	161	135.4 Å²	135.4	83%	0.826	72%	0.72	S	S	*	*	S	Bend	trans	-124	73.6	163.9	-55.2	178.6	0	0	0	107.1
449	G	34.8	Very low	34.2	Very low	59 Å²	59	133.6 Å²	133.6	61%	0.608	73%	0.729	S	S	*	*			trans	-179.4	115.4	176.5	0	0	0	0	0	109.9
450	I	31.7	Very low	33.2	Very low	164 Å²	164	134.1 Å²	134.1	84%	0.841	74%	0.735	S	S	*	*			trans	101.9	87.9	165.2	-49.3	174.9	0	0	0	116.3
451	R	28.9	Very low	32.4	Very low	236 Å²	236	138 Å²	138	89%	0.891	75%	0.745	S	S	*	*				47.6	122.4	126.8	-67.6	-178.3	-173.9	170.8	2.6	121.7
452	H	27.8	Very low	31.8	Very low	182 Å²	182	138.1 Å²	138.1	84%	0.843	75%	0.752	S	S	*	*			trans	0	123.3	130.2	-89.4	-74.1	0	0	0	116.9
453	L	28.8	Very low	31.7	Very low	173 Å²	173	138.6 Å²	138.6	91%	0.906	76%	0.761	S	S	*	*				-172	136.6	108.1	-99.1	149.7	0	0	0	110.9
454	D	28.2	Very low	31.2	Very low	163 Å²	163	136.1 Å²	136.1	87%	0.872	77%	0.766	S	S	*	*			trans	-70	152.7	179.1	-159.6	1	0	0	0	111.4
455	G	27.2	Very low	30.8	Very low	56 Å²	56	139.8 Å²	139.8	58%	0.577	78%	0.78	S	S	*	*			trans	154.3	91.8	169.3	0	0	0	0	0	118.3
456	T	28.3	Very low	30.4	Very low	141 Å²	141	141.5 Å²	141.5	87%	0.865	79%	0.786	S	S	*	*			trans	80.5	121	138.5	62.3	0	0	0	0	121.9
457	S	25.9	Very low	30	Very low	88 Å²	88	145 Å²	145	62%	0.615	79%	0.791	S	S	*	*				102.3	112.6	121.7	-179	0	0	0	0	120
458	K	28.4	Very low	29.7	Very low	207 Å²	207	146.9 Å²	146.9	90%	0.9	80%	0.802	S	S	*	*			trans	68.5	136.3	145.6	-65.9	170.4	-173	178.6	0	116
459	G	26.2	Very low	29.1	Very low	70 Å²	70	144 Å²	144	72%	0.722	80%	0.796	S	S	*	*			cis	152.5	138.1	9.9	0	0	0	0	0	108.1
460	N	25.1	Very low	28.7	Very low	155 Å²	155	146.4 Å²	146.4	83%	0.829	80%	0.802	S	S	*	*			trans	72	122.5	149.8	-130.4	18.3	0	0	0	119.9
461	I	29.5	Very low	28.9	Very low	150 Å²	150	148.7 Å²	148.7	77%	0.769	82%	0.824	S	S	*	*				156.8	123.2	116	-75.8	153.6	0	0	0	110.5
462	N	30.1	Very low	28.9	Very low	146 Å²	146	144.4 Å²	144.4	78%	0.781	82%	0.82	S	S	*	*			trans	-58	162.7	170.5	-63.6	-35.2	0	0	0	112.2
463	P	36.7	Very low	28.9	Very low	115 Å²	115	142.4 Å²	142.4	75%	0.747	82%	0.819	S	S	*	*				-152.2	145.1	88.6	36.5	-15	0	0	0	114.9
464	V	27.5	Very low	28.9	Very low	139 Å²	139	140.7 Å²	140.7	84%	0.842	82%	0.815	S	S	*	*				76.4	125.1	99.3	-175.2	0	0	0	0	115.6
465	N	29.7	Very low	29	Very low	148 Å²	148	139.4 Å²	139.4	79%	0.791	81%	0.811	S	S	*	*			trans	-44.4	147.5	165.2	-77.7	-28.6	0	0	0	114.1
466	E	28.7	Very low	29.1	Very low	190 Å²	190	144.6 Å²	144.6	89%	0.888	83%	0.826	S	S	*	*				-174	150.8	112	-111.1	-179.5	152.9	0	0	113.6
467	K	32.3	Very low	29.1	Very low	197 Å²	197	144.8 Å²	144.8	86%	0.857	82%	0.823	S	S	*	*			trans	-49.6	158.3	167.4	-67.9	166.1	173.4	171.3	0	111.5
468	V	29.2	Very low	29.3	Very low	144 Å²	144	148.9 Å²	148.9	87%	0.873	84%	0.838	S	S	*	*			trans	-167.3	145.9	130.2	144.5	0	0	0	0	111.1
469	S	26.5	Very low	29.4	Very low	101 Å²	101	144.4 Å²	144.4	71%	0.706	83%	0.833	S	S	*	*			trans	-73.5	-168.7	175.4	-177.7	0	0	0	0	112.7
470	C	25.4	Very low	29.7	Very low	109 Å²	109	150.6 Å²	150.6	74%	0.736	84%	0.843	S	S	*	*			trans	91.6	142.4	159.1	-50	0	0	0	0	114.3
471	V	35.6	Very low	30.1	Very low	213 Å²	213	150.2 Å²	150.2	100%	1.291	84%	0.844	S	S	*	*			cis	-143.7	0	16.4	170.4	0	0	0	0	108.2

Retrieved 471 of 471 residues in 237.8 ms (Link to these results)

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