A0A093HU13_STRCA Loading...

Antizyme inhibitor 1

Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding. Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production.

AlphaFold DB , UniProt , Accession A0A093HU13, Species STRCA (Struthio camelus australis), Gene n/a, Length 449 aa.

Structure Viewer
Loading PAE data...
(Predicted Aligned Error values between residue pairs)
Error loading PAE data: please refresh the page.

Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M28.7Very low46.5Very low245 Ų245123.2 Ų123.2100%1.20765%0.654SS**  0115.50-79.5167.4-152.300107G3M1-G3 PolarHBondContact O-N 2.94Å
2K28.7Very low49.5Very low189 Ų189113.1 Ų113.182%0.82260%0.6SS**  trans-72106.1166-77.5179.8171.8-173.70105.6F4K2-F4 PolarHBondContact O-N 2.89Å
3G25.5Very low52.1Low73 Ų73105.9 Ų105.975%0.75357%0.57SS**  trans-70.1105.4159.300000105.1M1 L5M1-G3 PolarHBondContact O-N 2.94Å; G3-L5 PolarHBondContact O-N 3.2Å
4F29Very low54.5Low182 Ų18299.8 Ų99.880%0.79854%0.537SS*.  trans-60124.8163.7-77.3-96.9000105.6K2 E6K2-F4 PolarHBondContact O-N 2.89Å; F4-E6 VanDerWaalsContact C-N 3.34Å; F4-E6 PolarHBondContact O-N 3.33Å
5L38.6Very low56.6Low107 Ų10793.5 Ų93.556%0.5650%0.503SS*.  trans-51.2112.7150-79.2148.5000104G3 D7 D100G3-L5 PolarHBondContact O-N 3.2Å; L5-D7 PolarHBondContact O-N 3.26Å; L5-D100 HydrophobicContact CD1-CB 4.47Å
6E38.6Very low58.1Low176 Ų17693.7 Ų93.782%0.82250%0.504SS*.  trans-47.7135.3161.2-75.4178.6150.500106.2F4 A8F4-E6 VanDerWaalsContact C-N 3.34Å; F4-E6 PolarHBondContact O-N 3.33Å; E6-A8 WeakPolarHBondContact O-CA 3.49Å; E6-A8 PolarHBondContact O-N 3.45Å
7D39.5Very low58.9Low145 Ų14599.1 Ų99.178%0.77553%0.525SS*.  trans-52.693.2177-71.7-43.5000108L5 N9L5-D7 PolarHBondContact O-N 3.26Å; D7-N9 PolarHBondContact O-N 2.96Å
8A56.1Low59.7Low35 Ų3597.2 Ų97.229%0.28953%0.534SS..  trans-82.881.3-169.100000106.4E6 Y10E6-A8 WeakPolarHBondContact O-CA 3.49Å; E6-A8 PolarHBondContact O-N 3.45Å; A8-Y10 HydrophobicContact CB-CE1 3.8Å; A8-Y10 VanDerWaalsContact CB-OH 3.27Å; A8-Y10 WeakPolarHBondContact CB-OH 3.27Å; A8-Y10 WeakPolarHBondContact O-CD2 3.29Å; A8-Y10 VanDerWaalsContact O-CE2 3.22Å; A8-Y10 WeakPolarHBondContact O-CE2 3.3Å; A8-Y10 PolarHBondContact O-N 3.36Å
9N69.3Low60.9Low95 Ų9593.4 Ų93.451%0.50852%0.516SS..  trans-68.3114.5172.5-68.4-16.8000108D7 N429 F431D7-N9 PolarHBondContact O-N 2.96Å; N9-N429 CarbonylContact C-O 3.49Å; N9-N429 WeakPolarHBondContact CA-O 3.47Å; N9-F431 HydrophobicContact CB-CD2 3.58Å; N9-F431 HydrophobicContact CB-CE2 3.41Å; N9-F431 VanDerWaalsContact CB-CE2 3.41Å; N9-F431 HydrophobicContact CB-CZ 4.35Å; N9-F431 WeakPolarHBondContact OD1-CE2 3.49Å
10Y77Confident62.2Low31 Ų3192.2 Ų92.212%0.12251%0.511CS..EExtended strand (participates in β ladder)trans-88110.7178-50.6-63.7000109A8 I12 P74 E78 Y406 N429 F430 F431A8-Y10 HydrophobicContact CB-CE1 3.8Å; A8-Y10 VanDerWaalsContact CB-OH 3.27Å; A8-Y10 WeakPolarHBondContact CB-OH 3.27Å; A8-Y10 WeakPolarHBondContact O-CD2 3.29Å; A8-Y10 VanDerWaalsContact O-CE2 3.22Å; A8-Y10 WeakPolarHBondContact O-CE2 3.3Å; A8-Y10 PolarHBondContact O-N 3.36Å; Y10-I12 PolarHBondContact O-N 2.95Å; Y10-P74 HydrophobicContact CE1-CB 4.22Å; Y10-P74 HydrophobicContact CE2-CB 4.26Å; Y10-P74 WeakPolarHBondContact OH-CB 3.36Å; Y10-E78 WeakPolarHBondContact CE2-OE2 3.31Å; Y10-Y406 HydrophobicContact CD1-CE2 4.3Å; Y10-N429 HydrophobicContact CD2-CB 3.94Å; Y10-N429 HydrophobicContact CE2-CB 3.82Å; Y10-N429 PolarHBondContact N-O 2.78Å; Y10-F430 HydrophobicContact CD2-CD1 4.02Å; Y10-F430 AromaticContact CD2-CE1 3.89Å; Y10-F430 HydrophobicContact CD2-CE1 3.89Å; Y10-F430 HydrophobicContact CD2-CZ 4.39Å; Y10-F430 HydrophobicContact CG-CD1 4.39Å; Y10-F430 HydrophobicContact CG-CE1 4.35Å; Y10-F431 PolarHBondContact O-N 2.75Å
11S80.7Confident63.4Low77 Ų7789.6 Ų89.654%0.53850%0.497SS..EExtended strand (participates in β ladder)trans-73.1117.1168-171.90000108.7F431S11-F431 WeakPolarHBondContact CA-O 3.48Å
12I81.9Confident66.3Low2 Ų280.4 Ų80.41%0.0146%0.46CS..EExtended strand (participates in β ladder)trans-105.2123.7172.8-60.5176.1000108.2Y10 L14 L45 I408 F430 F431 F432 V433Y10-I12 PolarHBondContact O-N 2.95Å; I12-L14 PolarHBondContact O-N 3.26Å; I12-L45 HydrophobicContact CD1-CD1 3.49Å; I12-L45 VanDerWaalsContact CD1-CD1 3.49Å; I12-L45 HydrophobicContact CG1-CD1 3.96Å; I12-I408 HydrophobicContact CG2-CB 4.15Å; I12-I408 HydrophobicContact CG2-CG2 3.69Å; I12-F430 HydrophobicContact CD1-CB 4Å; I12-F430 HydrophobicContact CD1-CD1 3.14Å; I12-F430 HydrophobicContact CD1-CE1 3.78Å; I12-F430 HydrophobicContact CD1-CG 3.83Å; I12-F430 HydrophobicContact CG1-CD1 3.93Å; I12-F431 PolarHBondContact N-O 3.46Å; I12-F432 HydrophobicContact CB-CD1 3.86Å; I12-F432 HydrophobicContact CB-CE1 3.91Å; I12-F432 HydrophobicContact CD1-CD1 4.21Å; I12-F432 HydrophobicContact CD1-CE1 3.41Å; I12-F432 VanDerWaalsContact CD1-CE1 3.41Å; I12-F432 HydrophobicContact CD1-CE2 4.38Å; I12-F432 HydrophobicContact CD1-CZ 3.49Å; I12-F432 VanDerWaalsContact CD1-CZ 3.49Å; I12-F432 HydrophobicContact CG1-CE1 4.24Å; I12-F432 HydrophobicContact CG2-CD1 3.9Å; I12-F432 HydrophobicContact CG2-CE1 3.84Å; I12-V433 PolarHBondContact O-N 3.19Å
13G83.8Confident69.3Low20 Ų2073.4 Ų73.421%0.20643%0.431CS..EExtended strand (participates in β ladder)trans-72.4116.2168.900000110.6Y406 M407 I408G13-Y406 PolarHBondContact N-O 3.08Å; G13-M407 VanDerWaalsContact O-CA 3.3Å; G13-M407 WeakPolarHBondContact O-CA 3.26Å; G13-I408 PolarHBondContact O-N 2.72Å
14L85.6Confident72.4Confident20 Ų2070.8 Ų70.811%0.10540%0.401CS..EExtended strand (participates in β ladder)trans-84.7113.9171.1-174.666.1000108.7I12 I408 F410 W413 V433 S435I12-L14 PolarHBondContact O-N 3.26Å; L14-I408 HydrophobicContact CD1-CG2 3.74Å; L14-F410 HydrophobicContact CD1-CD2 4.48Å; L14-F410 HydrophobicContact CD2-CD2 3.94Å; L14-F410 HydrophobicContact CD2-CE2 4.43Å; L14-F410 HydrophobicContact CG-CD2 4.3Å; L14-W413 HydrophobicContact CD1-CB 3.59Å; L14-W413 HydrophobicContact CD1-CG 3.69Å; L14-V433 PolarHBondContact N-O 3.13Å; L14-S435 WeakPolarHBondContact O-CB 3.5Å; L14-S435 PolarHBondContact O-N 2.82Å; L14-S435 PolarHBondContact O-OG 3.28Å
15L86.1Confident75.5Confident6 Ų662.8 Ų62.83%0.03137%0.366CS..EExtended strand (participates in β ladder)trans-83.8127.7-177.5-56.2-173.6000111.3A19 V24 M407 I408 F410 S435 I437L15-A19 HydrophobicContact CB-CB 4.18Å; L15-V24 HydrophobicContact CD1-CG2 3.91Å; L15-V24 HydrophobicContact CD2-CG2 3.47Å; L15-V24 VanDerWaalsContact CD2-CG2 3.47Å; L15-V24 HydrophobicContact CG-CG2 4.33Å; L15-M407 HydrophobicContact CD1-CB 4.42Å; L15-M407 HydrophobicContact CD1-CE 3.66Å; L15-M407 HydrophobicContact CD1-SD 3.53Å; L15-M407 VanDerWaalsContact CD1-SD 3.53Å; L15-M407 HydrophobicContact CG-CB 4.36Å; L15-M407 HydrophobicContact CG-CE 4.29Å; L15-M407 HydrophobicContact CG-SD 4.43Å; L15-I408 PolarHBondContact N-O 3.38Å; L15-F410 WeakPolarHBondContact O-CB 3.48Å; L15-F410 PolarHBondContact O-N 3.32Å; L15-S435 WeakPolarHBondContact CD2-OG 3.29Å; L15-I437 HydrophobicContact CD2-CD1 3.94Å
16D80.8Confident78.1Confident96 Ų9661.3 Ų61.351%0.51336%0.359SS..  trans-64.8160.3174.3-68-27.4000112G18 A19D16-G18 PolarHBondContact O-N 3.03Å; D16-A19 PolarHBondContact O-N 3.29Å; D16-A19 VanDerWaalsContact O-N 3.08Å
17E70.9Confident80.6Confident185 Ų18555.9 Ų55.986%0.86434%0.335SS*.THydrogen-bonded Turntrans-58.9102.2175-71.1-171.6167.400111.1
18G73.8Confident83.2Confident66 Ų6649.2 Ų49.268%0.6830%0.3SS*.THydrogen-bonded Turntrans121.4-16.2178.500000114.7D16D16-G18 PolarHBondContact O-N 3.03Å
19A82.1Confident84.9Confident24 Ų2448 Ų4820%0.19829%0.289CS..  trans-78.1139.9170.500000110.6L15 D16 I437L15-A19 HydrophobicContact CB-CB 4.18Å; D16-A19 PolarHBondContact O-N 3.29Å; D16-A19 VanDerWaalsContact O-N 3.08Å; A19-I437 HydrophobicContact CB-CD1 4.32Å
20T86.9Confident86.1Confident69 Ų6950.9 Ų50.942%0.42329%0.293SS..  trans-118.2166.5-175.369.10000111.7A22 D23 V24T20-A22 PolarHBondContact O-N 3Å; T20-A22 PolarHBondContact OG1-N 3.19Å; T20-D23 WeakPolarHBondContact CA-OD2 3.09Å; T20-D23 WeakPolarHBondContact CB-OD2 3.5Å; T20-D23 PolarHBondContact N-OD2 2.99Å; T20-D23 PolarHBondContact O-N 3.29Å; T20-D23 VanDerWaalsContact O-N 3.09Å; T20-D23 PolarHBondContact OG1-N 3.05Å; T20-D23 PolarHBondContact OG1-OD2 3.48Å; T20-V24 PolarHBondContact O-N 2.96Å
21L88.6Confident86.7Confident39 Ų3953.6 Ų53.620%0.20431%0.307CS..Hα-helixtrans-54.3-37.7171.1176.361.9000111.9V24 I25 V42 M407L21-V24 PolarHBondContact O-N 3.26Å; L21-I25 HydrophobicContact CD1-CD1 4.2Å; L21-I25 HydrophobicContact CD1-CG1 4.42Å; L21-I25 HydrophobicContact CG-CD1 3.93Å; L21-I25 WeakPolarHBondContact O-CG1 3.41Å; L21-I25 PolarHBondContact O-N 3.11Å; L21-V42 HydrophobicContact CD1-CB 3.94Å; L21-V42 HydrophobicContact CD1-CG1 3.42Å; L21-V42 VanDerWaalsContact CD1-CG1 3.42Å; L21-M407 HydrophobicContact CD1-SD 4.06Å
22A89.8Confident87.2Confident52 Ų5250.3 Ų50.343%0.4328%0.283SS..Hα-helixtrans-62.8-42.1177.400000111.5T20 V24 I25 D26T20-A22 PolarHBondContact O-N 3Å; T20-A22 PolarHBondContact OG1-N 3.19Å; A22-V24 VanDerWaalsContact C-N 3.28Å; A22-V24 PolarHBondContact O-N 2.9Å; A22-I25 PolarHBondContact O-N 3.49Å; A22-D26 WeakPolarHBondContact O-CB 3.49Å; A22-D26 VanDerWaalsContact O-CG 3.27Å; A22-D26 PolarHBondContact O-N 3.48Å
23D90.6Very high87.6Confident41 Ų4153 Ų5322%0.21930%0.3CS..Hα-helixtrans-62.9-36.2178-56.6-60.3000112T20 N27T20-D23 WeakPolarHBondContact CA-OD2 3.09Å; T20-D23 WeakPolarHBondContact CB-OD2 3.5Å; T20-D23 PolarHBondContact N-OD2 2.99Å; T20-D23 PolarHBondContact O-N 3.29Å; T20-D23 VanDerWaalsContact O-N 3.09Å; T20-D23 PolarHBondContact OG1-N 3.05Å; T20-D23 PolarHBondContact OG1-OD2 3.48Å; D23-N27 WeakPolarHBondContact O-CB 3.39Å; D23-N27 PolarHBondContact O-N 3.37Å
24V91.5Very high87.8Confident19 Ų1958.2 Ų58.212%0.11532%0.319CS..Hα-helixtrans-66.4-46.1174.5-178.80000110.9L15 T20 L21 A22 D26 N27 C28 V42 I437L15-V24 HydrophobicContact CD1-CG2 3.91Å; L15-V24 HydrophobicContact CD2-CG2 3.47Å; L15-V24 VanDerWaalsContact CD2-CG2 3.47Å; L15-V24 HydrophobicContact CG-CG2 4.33Å; T20-V24 PolarHBondContact O-N 2.96Å; L21-V24 PolarHBondContact O-N 3.26Å; A22-V24 VanDerWaalsContact C-N 3.28Å; A22-V24 PolarHBondContact O-N 2.9Å; V24-D26 VanDerWaalsContact C-N 3.34Å; V24-D26 PolarHBondContact O-N 3.31Å; V24-N27 PolarHBondContact O-N 2.86Å; V24-C28 WeakPolarHBondContact O-CB 3.39Å; V24-C28 PolarHBondContact O-N 2.99Å; V24-C28 PolarHBondContact O-SG 2.91Å; V24-C28 VanDerWaalsContact O-SG 3.35Å; V24-V42 HydrophobicContact CB-CG1 4.45Å; V24-V42 HydrophobicContact CG1-CG1 3.84Å; V24-V42 HydrophobicContact CG1-CG2 4.29Å; V24-I437 HydrophobicContact CG2-CD1 4.01Å
25I93.6Very high87.7Confident13 Ų1362.5 Ų62.57%0.06735%0.346CS..Hα-helixtrans-60.6-45.5177.8-70168000110.3L21 A22 N27 C28 I29 V42 T282 I381L21-I25 HydrophobicContact CD1-CD1 4.2Å; L21-I25 HydrophobicContact CD1-CG1 4.42Å; L21-I25 HydrophobicContact CG-CD1 3.93Å; L21-I25 WeakPolarHBondContact O-CG1 3.41Å; L21-I25 PolarHBondContact O-N 3.11Å; A22-I25 PolarHBondContact O-N 3.49Å; I25-N27 PolarHBondContact O-N 3.48Å; I25-C28 PolarHBondContact O-N 2.79Å; I25-I29 HydrophobicContact CG2-CD1 3.88Å; I25-I29 WeakPolarHBondContact O-CB 3.35Å; I25-I29 PolarHBondContact O-N 3.49Å; I25-V42 HydrophobicContact CG1-CB 4.27Å; I25-V42 HydrophobicContact CG1-CG2 3.75Å; I25-T282 HydrophobicContact CD1-CG2 3.68Å; I25-I381 HydrophobicContact CD1-CG2 4.49Å; I25-I381 HydrophobicContact CG2-CD1 3.71Å
26D93.3Very high87.6Confident76 Ų7664.8 Ų64.841%0.40637%0.371SS..Hα-helixtrans-60-45.7178.3-734.2000111A22 V24 I29 Y30 H340A22-D26 WeakPolarHBondContact O-CB 3.49Å; A22-D26 VanDerWaalsContact O-CG 3.27Å; A22-D26 PolarHBondContact O-N 3.48Å; V24-D26 VanDerWaalsContact C-N 3.34Å; V24-D26 PolarHBondContact O-N 3.31Å; D26-I29 PolarHBondContact O-N 2.86Å; D26-Y30 PolarHBondContact O-N 2.9Å; D26-H340 IonicContact OD1-CD2 3.45Å; D26-H340 PolarHBondContact OD1-CD2 3.13Å; D26-H340 IonicContact OD1-NE2 3.43Å; D26-H340 PolarHBondContact OD1-NE2 3.18Å
27N91.3Very high88Confident62 Ų6263.4 Ų63.433%0.33236%0.36SS..Hα-helixtrans-63.6-45.2176.6-17570.1000112D23 V24 I25 I29 Y30 E31D23-N27 WeakPolarHBondContact O-CB 3.39Å; D23-N27 PolarHBondContact O-N 3.37Å; V24-N27 PolarHBondContact O-N 2.86Å; I25-N27 PolarHBondContact O-N 3.48Å; N27-I29 VanDerWaalsContact C-N 3.34Å; N27-I29 PolarHBondContact O-N 3.01Å; N27-Y30 WeakPolarHBondContact O-CB 3.46Å; N27-Y30 PolarHBondContact O-N 2.91Å; N27-E31 PolarHBondContact ND2-OE1 3.08Å; N27-E31 PolarHBondContact O-N 3.14Å
28C92.7Very high89Confident5 Ų559.1 Ų59.13%0.03434%0.336CS..Hα-helixtrans-61.8-41.8175.8-71.80000111.4V24 I25 Y30 E31 H32 F40V24-C28 WeakPolarHBondContact O-CB 3.39Å; V24-C28 PolarHBondContact O-N 2.99Å; V24-C28 PolarHBondContact O-SG 2.91Å; V24-C28 VanDerWaalsContact O-SG 3.35Å; I25-C28 PolarHBondContact O-N 2.79Å; C28-Y30 VanDerWaalsContact C-N 3.31Å; C28-Y30 PolarHBondContact O-N 3.12Å; C28-E31 PolarHBondContact O-N 3.46Å; C28-H32 WeakPolarHBondContact O-CB 3.48Å; C28-H32 PolarHBondContact O-CD2 3.01Å; C28-H32 PolarHBondContact O-N 3.35Å; C28-F40 HydrophobicContact CB-CD2 4.03Å; C28-F40 HydrophobicContact CB-CE1 4.01Å; C28-F40 HydrophobicContact CB-CE2 3.31Å; C28-F40 HydrophobicContact CB-CZ 3.3Å
29I93.7Very high90Very high10 Ų1056.4 Ų56.45%0.05131%0.307CS..Hα-helixtrans-60.6-42174.8-83.4169.3000111.2I25 D26 N27 H32 T33 F40 H340 W379 I381I25-I29 HydrophobicContact CG2-CD1 3.88Å; I25-I29 WeakPolarHBondContact O-CB 3.35Å; I25-I29 PolarHBondContact O-N 3.49Å; D26-I29 PolarHBondContact O-N 2.86Å; N27-I29 VanDerWaalsContact C-N 3.34Å; N27-I29 PolarHBondContact O-N 3.01Å; I29-H32 PolarHBondContact O-N 3.4Å; I29-T33 VanDerWaalsContact O-CB 3.24Å; I29-T33 WeakPolarHBondContact O-CB 3.45Å; I29-T33 PolarHBondContact O-N 2.8Å; I29-T33 PolarHBondContact O-OG1 3.3Å; I29-F40 HydrophobicContact CG1-CE1 3.93Å; I29-F40 HydrophobicContact CG1-CZ 3.83Å; I29-H340 HydrophobicContact CD1-CB 4.21Å; I29-H340 WeakPolarHBondContact CD1-CD2 3.12Å; I29-W379 HydrophobicContact CD1-CB 3.81Å; I29-W379 HydrophobicContact CD1-CD2 4.13Å; I29-W379 HydrophobicContact CD1-CE3 4.44Å; I29-W379 HydrophobicContact CD1-CG 3.86Å; I29-W379 HydrophobicContact CG1-CB 4.43Å; I29-W379 HydrophobicContact CG1-CD2 3.78Å; I29-W379 HydrophobicContact CG1-CE3 4.1Å; I29-W379 HydrophobicContact CG1-CG 3.93Å; I29-W379 HydrophobicContact CG2-CD2 4.48Å; I29-W379 HydrophobicContact CG2-CG 4.15Å; I29-I381 HydrophobicContact CD1-CD1 3.89Å
30Y92.8Very high90.6Very high155 Ų15555.3 Ų55.361%0.60830%0.298SS*.Hα-helixtrans-59.1-50.7175.7177.6-94.4000111.3D26 N27 C28 T33 H34D26-Y30 PolarHBondContact O-N 2.9Å; N27-Y30 WeakPolarHBondContact O-CB 3.46Å; N27-Y30 PolarHBondContact O-N 2.91Å; C28-Y30 VanDerWaalsContact C-N 3.31Å; C28-Y30 PolarHBondContact O-N 3.12Å; Y30-T33 PolarHBondContact O-N 2.61Å; Y30-H34 AromaticContact CE2-CE1 3.7Å; Y30-H34 AromaticContact CZ-CE1 3.86Å; Y30-H34 PolarHBondContact O-ND1 3.44Å
31E90.8Very high91.1Very high89 Ų8952 Ų5242%0.41628%0.278SS..Hα-helixtrans-62.5-45.6178.2-70.5-178.6-173.400112.5N27 C28 T33 H34 T35N27-E31 PolarHBondContact ND2-OE1 3.08Å; N27-E31 PolarHBondContact O-N 3.14Å; C28-E31 PolarHBondContact O-N 3.46Å; E31-T33 VanDerWaalsContact C-N 3.3Å; E31-T33 PolarHBondContact O-N 3.06Å; E31-H34 PolarHBondContact O-N 3.47Å; E31-H34 VanDerWaalsContact O-N 3.13Å; E31-T35 WeakPolarHBondContact O-CG2 3.44Å; E31-T35 PolarHBondContact O-N 3.09Å; E31-T35 PolarHBondContact O-OG1 3.38Å
32H91.6Very high91.4Very high8 Ų850.2 Ų50.24%0.03727%0.269CS..Hα-helixtrans-66.4-32.6-179.9-84.6-70.7000112.5C28 I29 H34 T35 G36 K37 F40 W379 Y405C28-H32 WeakPolarHBondContact O-CB 3.48Å; C28-H32 PolarHBondContact O-CD2 3.01Å; C28-H32 PolarHBondContact O-N 3.35Å; I29-H32 PolarHBondContact O-N 3.4Å; H32-H34 PolarHBondContact O-N 2.95Å; H32-T35 WeakPolarHBondContact CA-OG1 3.32Å; H32-T35 PolarHBondContact O-N 2.82Å; H32-G36 PolarHBondContact O-N 3.41Å; H32-G36 VanDerWaalsContact O-N 3.11Å; H32-K37 WeakPolarHBondContact O-CA 3.24Å; H32-K37 PolarHBondContact O-N 3.25Å; H32-F40 AromaticContact CD2-CD1 3.53Å; H32-F40 AromaticContact CD2-CE1 3.86Å; H32-W379 HydrophobicContact CB-CH2 3.82Å; H32-W379 HydrophobicContact CB-CZ2 3.84Å; H32-Y405 AromaticContact NE2-CE2 3.56Å; H32-Y405 AromaticContact NE2-CZ 3.6Å; H32-Y405 PolarHBondContact NE2-OH 3.02Å
33T90.1Very high91.6Very high58 Ų5847.7 Ų47.736%0.35625%0.248SC..Hα-helixtrans-59.7-27.8175.1-64.70000112.2I29 Y30 E31 W379I29-T33 VanDerWaalsContact O-CB 3.24Å; I29-T33 WeakPolarHBondContact O-CB 3.45Å; I29-T33 PolarHBondContact O-N 2.8Å; I29-T33 PolarHBondContact O-OG1 3.3Å; Y30-T33 PolarHBondContact O-N 2.61Å; E31-T33 VanDerWaalsContact C-N 3.3Å; E31-T33 PolarHBondContact O-N 3.06Å; T33-W379 PolarHBondContact OG1-NE1 2.92Å
34H87.1Confident91.8Very high130 Ų13046.6 Ų46.660%0.60224%0.242SC*.Hα-helixtrans-97.3-11.1179.5-62.488.4000114.4Y30 E31 H32Y30-H34 AromaticContact CE2-CE1 3.7Å; Y30-H34 AromaticContact CZ-CE1 3.86Å; Y30-H34 PolarHBondContact O-ND1 3.44Å; E31-H34 PolarHBondContact O-N 3.47Å; E31-H34 VanDerWaalsContact O-N 3.13Å; H32-H34 PolarHBondContact O-N 2.95Å
35T83.3Confident91.8Very high109 Ų10945.7 Ų45.767%0.66924%0.237SC*.Hα-helixtrans-121-7.9-169.954.10000115.1E31 H32E31-T35 WeakPolarHBondContact O-CG2 3.44Å; E31-T35 PolarHBondContact O-N 3.09Å; E31-T35 PolarHBondContact O-OG1 3.38Å; H32-T35 WeakPolarHBondContact CA-OG1 3.32Å; H32-T35 PolarHBondContact O-N 2.82Å
36G84.1Confident91.8Very high55 Ų5545.1 Ų45.157%0.56723%0.234SC*.THydrogen-bonded Turntrans144.94.4171.500000116.5H32 R38H32-G36 PolarHBondContact O-N 3.41Å; H32-G36 VanDerWaalsContact O-N 3.11Å; G36-R38 VanDerWaalsContact C-N 3.27Å; G36-R38 PolarHBondContact O-N 3.32Å
37K90.3Very high91.8Very high67 Ų6744.4 Ų44.429%0.29123%0.227SC..  trans52.242.1177.1-62.6-176.2177.7-165.80113.4H32 N286 N318 G377 W379H32-K37 WeakPolarHBondContact O-CA 3.24Å; H32-K37 PolarHBondContact O-N 3.25Å; K37-N286 HydrophobicContact CB-CB 4.28Å; K37-N318 PolarHBondContact O-ND2 2.85Å; K37-G377 VanDerWaalsContact NZ-CA 3.34Å; K37-G377 PolarHBondContact NZ-O 3.5Å; K37-W379 HydrophobicContact CB-CH2 4.4Å; K37-W379 HydrophobicContact CB-CZ2 4Å; K37-W379 HydrophobicContact CG-CZ2 4.15Å
38R92Very high92Very high94 Ų9441.5 Ų41.536%0.35521%0.211SC..  trans-74.7143.2177.5-67.4-178.961.5177.4-2.9109.8G36 W379G36-R38 VanDerWaalsContact C-N 3.27Å; G36-R38 PolarHBondContact O-N 3.32Å; R38-W379 WeakPolarHBondContact O-CH2 3.27Å
39A94.4Very high92Very high9 Ų941.4 Ų41.47%0.07421%0.211CC..  trans-59.8146.5170.100000110.3A284 V285 N318 D319 P402 L403A39-A284 VanDerWaalsContact CA-O 3.26Å; A39-A284 WeakPolarHBondContact CA-O 3.5Å; A39-V285 HydrophobicContact CB-CG1 4.27Å; A39-N318 PolarHBondContact N-ND2 3.04Å; A39-N318 VanDerWaalsContact N-ND2 3.14Å; A39-D319 HydrophobicContact CB-CB 4.34Å; A39-P402 HydrophobicContact CB-CB 4.25Å; A39-P402 HydrophobicContact CB-CG 4.02Å; A39-P402 WeakPolarHBondContact O-CA 3.47Å; A39-P402 WeakPolarHBondContact O-CB 3.25Å; A39-L403 PolarHBondContact O-N 2.98Å
40F94.9Very high92Very high1 Ų145.4 Ų45.40%0.00423%0.228CC..EExtended strand (participates in β ladder)trans-150.3154.7179.668.1-92.6000112C28 I29 H32 V42 A284 W379 L403 Y405C28-F40 HydrophobicContact CB-CD2 4.03Å; C28-F40 HydrophobicContact CB-CE1 4.01Å; C28-F40 HydrophobicContact CB-CE2 3.31Å; C28-F40 HydrophobicContact CB-CZ 3.3Å; I29-F40 HydrophobicContact CG1-CE1 3.93Å; I29-F40 HydrophobicContact CG1-CZ 3.83Å; H32-F40 AromaticContact CD2-CD1 3.53Å; H32-F40 AromaticContact CD2-CE1 3.86Å; F40-V42 HydrophobicContact CD2-CG2 4.06Å; F40-V42 HydrophobicContact CE2-CG2 3.77Å; F40-A284 HydrophobicContact CD1-CB 4.13Å; F40-A284 HydrophobicContact CD2-CB 4.33Å; F40-A284 HydrophobicContact CE1-CB 3.65Å; F40-A284 HydrophobicContact CE2-CB 3.88Å; F40-A284 HydrophobicContact CG-CB 4.44Å; F40-A284 HydrophobicContact CZ-CB 3.52Å; F40-A284 PolarHBondContact N-O 3.14Å; F40-A284 VanDerWaalsContact N-O 3.08Å; F40-A284 PolarHBondContact O-N 3.07Å; F40-W379 HydrophobicContact CD1-CH2 4.2Å; F40-W379 HydrophobicContact CD1-CZ3 4.04Å; F40-W379 HydrophobicContact CE1-CE3 4.42Å; F40-W379 AromaticContact CE1-CH2 3.99Å; F40-W379 HydrophobicContact CE1-CH2 3.99Å; F40-W379 AromaticContact CE1-CZ3 3.79Å; F40-W379 HydrophobicContact CE1-CZ3 3.79Å; F40-L403 CarbonylContact C-O 3.46Å; F40-L403 WeakPolarHBondContact CA-O 3.44Å; F40-L403 HydrophobicContact CB-CB 4.37Å; F40-Y405 HydrophobicContact CB-CD2 4.13Å; F40-Y405 HydrophobicContact CB-CE2 3.83Å; F40-Y405 AromaticContact CD2-CD2 3.89Å; F40-Y405 HydrophobicContact CD2-CD2 3.89Å; F40-Y405 HydrophobicContact CD2-CE2 4.12Å; F40-Y405 HydrophobicContact CG-CD2 4.27Å; F40-Y405 HydrophobicContact CG-CE2 4.07Å
41Y95.8Very high92.1Very high0 Ų039.4 Ų39.40%021%0.205CC..EExtended strand (participates in β ladder)trans-100.4145.7171.5-81.1-80.6000111.2F281 T282 L283 S324 M385 T389 L390 P402 L403 I404 Y405Y41-F281 HydrophobicContact CD1-CB 4.03Å; Y41-F281 HydrophobicContact CD1-CD1 4.23Å; Y41-F281 HydrophobicContact CE1-CB 4.37Å; Y41-T282 CarbonylContact C-O 3.57Å; Y41-T282 VanDerWaalsContact CA-O 3.32Å; Y41-T282 WeakPolarHBondContact CA-O 3.39Å; Y41-L283 HydrophobicContact CD1-CB 4.04Å; Y41-L283 HydrophobicContact CD1-CD1 4.36Å; Y41-L283 HydrophobicContact CD2-CD1 4.02Å; Y41-L283 HydrophobicContact CE1-CB 3.63Å; Y41-L283 HydrophobicContact CE1-CD1 4.1Å; Y41-L283 HydrophobicContact CE1-CG 4.32Å; Y41-L283 HydrophobicContact CE2-CD1 3.72Å; Y41-L283 HydrophobicContact CG-CD1 4.33Å; Y41-S324 WeakPolarHBondContact OH-CB 3.42Å; Y41-S324 PolarHBondContact OH-OG 2.98Å; Y41-M385 HydrophobicContact CE1-CB 3.78Å; Y41-M385 VanDerWaalsContact CE1-O 3.23Å; Y41-M385 WeakPolarHBondContact CE1-O 3.49Å; Y41-T389 VanDerWaalsContact OH-CB 3.27Å; Y41-T389 WeakPolarHBondContact OH-CB 3.46Å; Y41-T389 PolarHBondContact OH-OG1 3.49Å; Y41-L390 HydrophobicContact CD2-CD2 3.62Å; Y41-L390 HydrophobicContact CD2-CG 4.44Å; Y41-L390 HydrophobicContact CE2-CD2 3.41Å; Y41-L390 VanDerWaalsContact CE2-CD2 3.41Å; Y41-L390 HydrophobicContact CE2-CG 4.03Å; Y41-L390 HydrophobicContact CG-CD2 4.41Å; Y41-P402 HydrophobicContact CD2-CB 3.82Å; Y41-P402 HydrophobicContact CD2-CG 4.47Å; Y41-P402 HydrophobicContact CE2-CB 4.03Å; Y41-P402 HydrophobicContact CE2-CG 4.18Å; Y41-L403 PolarHBondContact N-O 3.34Å; Y41-I404 HydrophobicContact CD2-CG1 4.48Å; Y41-Y405 PolarHBondContact O-N 3.3Å
42V95.7Very high92.4Very high1 Ų135.5 Ų35.51%0.00619%0.187CC..EExtended strand (participates in β ladder)trans-113.2121158.1-172.90000108.2L21 V24 I25 F40 F281 T282 Y405 M407L21-V42 HydrophobicContact CD1-CB 3.94Å; L21-V42 HydrophobicContact CD1-CG1 3.42Å; L21-V42 VanDerWaalsContact CD1-CG1 3.42Å; V24-V42 HydrophobicContact CB-CG1 4.45Å; V24-V42 HydrophobicContact CG1-CG1 3.84Å; V24-V42 HydrophobicContact CG1-CG2 4.29Å; I25-V42 HydrophobicContact CG1-CB 4.27Å; I25-V42 HydrophobicContact CG1-CG2 3.75Å; F40-V42 HydrophobicContact CD2-CG2 4.06Å; F40-V42 HydrophobicContact CE2-CG2 3.77Å; V42-F281 WeakPolarHBondContact O-CA 3.49Å; V42-T282 PolarHBondContact N-O 3.29Å; V42-T282 PolarHBondContact O-N 3.22Å; V42-Y405 CarbonylContact C-O 3.6Å; V42-Y405 WeakPolarHBondContact CA-O 3.49Å; V42-M407 HydrophobicContact CG1-CG 3.9Å
43G95.1Very high92.5Very high0 Ų038 Ų380%020%0.199CC..EExtended strand (participates in β ladder)trans-108.8114.8179.700000111.5L45 A280 Y405 Y406 M407G43-L45 PolarHBondContact O-N 3.05Å; G43-A280 CarbonylContact C-O 3.55Å; G43-A280 WeakPolarHBondContact CA-O 3.03Å; G43-Y405 PolarHBondContact N-O 3.26Å; G43-Y406 WeakPolarHBondContact O-CA 3.42Å; G43-M407 PolarHBondContact O-N 3.09Å
44D94.4Very high92.7Very high17 Ų1736.3 Ų36.39%0.09119%0.187CC..EExtended strand (participates in β ladder)trans-86.2103.4173.9179.3-8.1000109.9G46 K47 A280 M407D44-G46 VanDerWaalsContact C-N 3.33Å; D44-G46 WeakPolarHBondContact OD1-CA 3.47Å; D44-G46 PolarHBondContact OD1-N 2.94Å; D44-K47 HydrophobicContact CB-CD 4.07Å; D44-K47 HydrophobicContact CB-CG 4.32Å; D44-K47 PolarHBondContact O-N 3.32Å; D44-K47 PolarHBondContact OD1-N 2.95Å; D44-K47 WeakPolarHBondContact OD2-CE 3.5Å; D44-K47 WeakPolarHBondContact OD2-CG 3.41Å; D44-A280 PolarHBondContact N-O 3.44Å; D44-M407 HydrophobicContact CB-CE 4Å; D44-M407 HydrophobicContact CB-CG 4.37Å; D44-M407 HydrophobicContact CB-SD 4.04Å; D44-M407 WeakPolarHBondContact OD1-CE 3.28Å
45L91.8Very high93.2Very high1 Ų130.2 Ų30.21%0.00516%0.159CC..Hα-helixtrans-75-24.2-177.5-63.1-179.2000112.4I12 G43 K47 L48 I79 Y406 M407 F430I12-L45 HydrophobicContact CD1-CD1 3.49Å; I12-L45 VanDerWaalsContact CD1-CD1 3.49Å; I12-L45 HydrophobicContact CG1-CD1 3.96Å; G43-L45 PolarHBondContact O-N 3.05Å; L45-K47 VanDerWaalsContact C-N 3.27Å; L45-K47 PolarHBondContact O-N 3.16Å; L45-L48 HydrophobicContact CD2-CD1 3.88Å; L45-L48 WeakPolarHBondContact O-CB 3.43Å; L45-L48 PolarHBondContact O-N 3.26Å; L45-L48 VanDerWaalsContact O-N 3.14Å; L45-I79 HydrophobicContact CB-CD1 3.64Å; L45-I79 HydrophobicContact CD1-CD1 3.66Å; L45-I79 HydrophobicContact CD2-CD1 3.96Å; L45-I79 HydrophobicContact CG-CD1 3.93Å; L45-Y406 HydrophobicContact CD1-CD1 3.95Å; L45-Y406 HydrophobicContact CD1-CG 3.98Å; L45-Y406 HydrophobicContact CD2-CD1 3.62Å; L45-Y406 HydrophobicContact CD2-CE1 3.94Å; L45-Y406 HydrophobicContact CD2-CG 4.48Å; L45-Y406 HydrophobicContact CG-CD1 3.87Å; L45-Y406 HydrophobicContact CG-CG 4.35Å; L45-M407 PolarHBondContact N-O 2.92Å; L45-F430 HydrophobicContact CD1-CE1 4.24Å
46G92.1Very high93.8Very high0 Ų030 Ų300%015%0.15CC..Hα-helixtrans-64.4-33.4175.500000112D44 L48 V49 K50D44-G46 VanDerWaalsContact C-N 3.33Å; D44-G46 WeakPolarHBondContact OD1-CA 3.47Å; D44-G46 PolarHBondContact OD1-N 2.94Å; G46-L48 VanDerWaalsContact C-N 3.29Å; G46-L48 PolarHBondContact O-N 3.4Å; G46-V49 PolarHBondContact O-N 2.79Å; G46-K50 PolarHBondContact O-N 2.76Å
47K94.1Very high94.3Very high62 Ų6233.9 Ų33.927%0.2716%0.158SC..Hα-helixtrans-60.4-34.2172.7-79.4176.4-178.6173.90113.4D44 L45 V49 K50 K51 S279 A280D44-K47 HydrophobicContact CB-CD 4.07Å; D44-K47 HydrophobicContact CB-CG 4.32Å; D44-K47 PolarHBondContact O-N 3.32Å; D44-K47 PolarHBondContact OD1-N 2.95Å; D44-K47 WeakPolarHBondContact OD2-CE 3.5Å; D44-K47 WeakPolarHBondContact OD2-CG 3.41Å; L45-K47 VanDerWaalsContact C-N 3.27Å; L45-K47 PolarHBondContact O-N 3.16Å; K47-V49 VanDerWaalsContact C-N 3.33Å; K47-V49 PolarHBondContact O-N 2.81Å; K47-K50 PolarHBondContact O-N 2.84Å; K47-K51 WeakPolarHBondContact O-CB 3.47Å; K47-K51 VanDerWaalsContact O-CG 3.26Å; K47-K51 WeakPolarHBondContact O-CG 3.43Å; K47-K51 PolarHBondContact O-N 3.06Å; K47-S279 VanDerWaalsContact CD-O 3.29Å; K47-S279 WeakPolarHBondContact CD-O 3.39Å; K47-S279 PolarHBondContact NZ-O 3.37Å; K47-A280 HydrophobicContact CB-CB 4.18Å
48L94.8Very high94.6Very high0 Ų031.6 Ų31.60%015%0.15CC..Hα-helixtrans-63.3-42.8177.4-56.4179.8000111L45 G46 K51 N52 V76 I79 L80 Y276 V277 A280L45-L48 HydrophobicContact CD2-CD1 3.88Å; L45-L48 WeakPolarHBondContact O-CB 3.43Å; L45-L48 PolarHBondContact O-N 3.26Å; L45-L48 VanDerWaalsContact O-N 3.14Å; G46-L48 VanDerWaalsContact C-N 3.29Å; G46-L48 PolarHBondContact O-N 3.4Å; L48-K51 PolarHBondContact O-N 2.96Å; L48-N52 PolarHBondContact O-N 3.28Å; L48-V76 HydrophobicContact CD1-CB 4.43Å; L48-V76 HydrophobicContact CD1-CG1 4.32Å; L48-V76 HydrophobicContact CD1-CG2 4.14Å; L48-I79 HydrophobicContact CB-CG2 4.25Å; L48-I79 HydrophobicContact CD1-CG2 4.25Å; L48-L80 HydrophobicContact CB-CD2 4.44Å; L48-Y276 VanDerWaalsContact CD2-O 3.23Å; L48-Y276 WeakPolarHBondContact CD2-O 3.39Å; L48-V277 HydrophobicContact CD2-CG1 3.96Å; L48-A280 HydrophobicContact CD2-CB 3.86Å
49V93Very high94.7Very high4 Ų427.1 Ų27.12%0.02413%0.133CC..Hα-helixtrans-65.5-47.8178.1-179.60000110.5G46 K47 K51 N52 M53 I79 L83 M416G46-V49 PolarHBondContact O-N 2.79Å; K47-V49 VanDerWaalsContact C-N 3.33Å; K47-V49 PolarHBondContact O-N 2.81Å; V49-K51 VanDerWaalsContact C-N 3.29Å; V49-K51 PolarHBondContact O-N 3.4Å; V49-N52 WeakPolarHBondContact O-CB 3.38Å; V49-N52 PolarHBondContact O-N 3Å; V49-M53 HydrophobicContact CG1-CE 3.85Å; V49-M53 WeakPolarHBondContact O-CG 3.41Å; V49-M53 PolarHBondContact O-N 3.43Å; V49-I79 HydrophobicContact CG2-CG2 4.31Å; V49-L83 HydrophobicContact CG2-CD1 4.35Å; V49-M416 HydrophobicContact CG1-CG 4.16Å; V49-M416 HydrophobicContact CG2-CE 4.07Å; V49-M416 HydrophobicContact CG2-CG 3.88Å; V49-M416 HydrophobicContact CG2-SD 3.72Å
50K93.8Very high94.4Very high93 Ų9330.2 Ų30.240%0.40416%0.158SC..Hα-helixtrans-56.8-42.1174.9-75.2171.1170.4152.90112.3G46 K47 N52 M53 Q54 D412G46-K50 PolarHBondContact O-N 2.76Å; K47-K50 PolarHBondContact O-N 2.84Å; K50-N52 VanDerWaalsContact C-N 3.33Å; K50-N52 PolarHBondContact O-N 3.15Å; K50-M53 PolarHBondContact O-N 3.47Å; K50-Q54 VanDerWaalsContact O-CB 3.31Å; K50-Q54 WeakPolarHBondContact O-CB 3.38Å; K50-Q54 PolarHBondContact O-N 3.19Å; K50-D412 WeakPolarHBondContact CE-OD1 3.29Å; K50-D412 IonicContact NZ-OD1 3.03Å; K50-D412 PolarHBondContact NZ-OD1 3.35Å; K50-D412 IonicContact NZ-OD2 2.62Å; K50-D412 PolarHBondContact NZ-OD2 3.45Å
51K95.9Very high94.1Very high30 Ų3032.9 Ų32.913%0.1318%0.176CC..Hα-helixtrans-62.8-39.8174.7-73.4-69.7163.7-152.30112K47 L48 V49 Q54 W55 G240 Y275 Y276K47-K51 WeakPolarHBondContact O-CB 3.47Å; K47-K51 VanDerWaalsContact O-CG 3.26Å; K47-K51 WeakPolarHBondContact O-CG 3.43Å; K47-K51 PolarHBondContact O-N 3.06Å; L48-K51 PolarHBondContact O-N 2.96Å; V49-K51 VanDerWaalsContact C-N 3.29Å; V49-K51 PolarHBondContact O-N 3.4Å; K51-Q54 PolarHBondContact O-N 3.21Å; K51-W55 WeakPolarHBondContact O-CB 3.39Å; K51-W55 PolarHBondContact O-N 2.9Å; K51-G240 PolarHBondContact NZ-O 3.32Å; K51-Y275 HydrophobicContact CB-CD1 4.49Å; K51-Y275 HydrophobicContact CB-CE1 3.89Å; K51-Y275 HydrophobicContact CD-CE1 4.14Å; K51-Y275 HydrophobicContact CD-CE2 4.24Å; K51-Y275 WeakPolarHBondContact CD-O 3.37Å; K51-Y275 WeakPolarHBondContact O-CE1 3.37Å; K51-Y275 PolarHBondContact O-OH 3.26Å; K51-Y276 HydrophobicContact CB-CD1 3.74Å; K51-Y276 HydrophobicContact CB-CE1 4.02Å
52N95.6Very high94.2Very high6 Ų633.1 Ų33.13%0.03218%0.177CC..Hα-helixtrans-67.1-42.6176-175.958.8000112L48 V49 K50 Q54 W55 Q56 L83 I85 Y276L48-N52 PolarHBondContact O-N 3.28Å; V49-N52 WeakPolarHBondContact O-CB 3.38Å; V49-N52 PolarHBondContact O-N 3Å; K50-N52 VanDerWaalsContact C-N 3.33Å; K50-N52 PolarHBondContact O-N 3.15Å; N52-Q54 VanDerWaalsContact C-N 3.32Å; N52-Q54 PolarHBondContact O-N 3.21Å; N52-W55 WeakPolarHBondContact O-CB 3.33Å; N52-W55 PolarHBondContact O-N 3.41Å; N52-Q56 PolarHBondContact ND2-NE2 3.04Å; N52-Q56 WeakPolarHBondContact O-CG 3.41Å; N52-Q56 PolarHBondContact O-N 2.86Å; N52-L83 HydrophobicContact CB-CD1 3.86Å; N52-I85 HydrophobicContact CB-CD1 4.39Å; N52-Y276 HydrophobicContact CB-CE1 3.88Å; N52-Y276 PolarHBondContact OD1-OH 3.3Å
53M93.7Very high94.2Very high60 Ų6036.9 Ų36.930%0.29619%0.193SC..Hα-helixtrans-59.8-44.7175-69.3177.7175.800111.3V49 K50 W55 Q56 N57V49-M53 HydrophobicContact CG1-CE 3.85Å; V49-M53 WeakPolarHBondContact O-CG 3.41Å; V49-M53 PolarHBondContact O-N 3.43Å; K50-M53 PolarHBondContact O-N 3.47Å; M53-W55 PolarHBondContact O-N 3.48Å; M53-Q56 PolarHBondContact O-N 3.14Å; M53-N57 PolarHBondContact O-N 3.41Å; M53-N57 PolarHBondContact O-ND2 2.87Å
54Q95.6Very high94.4Very high23 Ų2337.5 Ų37.511%0.10720%0.197CC..Hα-helixtrans-59.8-44.9175-172.3-170.1-5.800111.7K50 K51 N52 Q56 N57 V58 L245K50-Q54 VanDerWaalsContact O-CB 3.31Å; K50-Q54 WeakPolarHBondContact O-CB 3.38Å; K50-Q54 PolarHBondContact O-N 3.19Å; K51-Q54 PolarHBondContact O-N 3.21Å; N52-Q54 VanDerWaalsContact C-N 3.32Å; N52-Q54 PolarHBondContact O-N 3.21Å; Q54-Q56 PolarHBondContact O-N 3.34Å; Q54-N57 PolarHBondContact O-N 3.25Å; Q54-V58 PolarHBondContact O-N 2.99Å; Q54-L245 HydrophobicContact CG-CD2 4.34Å
55W97.3Very high94.6Very high3 Ų337 Ų371%0.01119%0.194CC..Hα-helixtrans-58.8-47.1174.4-177.5-83.9000111.5K51 N52 M53 N57 V58 M59 I62 P64 F238 L245 A270 P272 Y275K51-W55 WeakPolarHBondContact O-CB 3.39Å; K51-W55 PolarHBondContact O-N 2.9Å; N52-W55 WeakPolarHBondContact O-CB 3.33Å; N52-W55 PolarHBondContact O-N 3.41Å; M53-W55 PolarHBondContact O-N 3.48Å; W55-N57 VanDerWaalsContact C-N 3.28Å; W55-N57 PolarHBondContact O-N 3.33Å; W55-V58 PolarHBondContact O-N 2.93Å; W55-M59 HydrophobicContact CD2-CB 3.94Å; W55-M59 HydrophobicContact CD2-CG 4.16Å; W55-M59 HydrophobicContact CE3-CB 4.5Å; W55-M59 HydrophobicContact CE3-CG 4.21Å; W55-M59 HydrophobicContact CG-CB 4.26Å; W55-M59 HydrophobicContact CH2-CB 4.48Å; W55-M59 HydrophobicContact CH2-CE 4.32Å; W55-M59 HydrophobicContact CH2-CG 4.21Å; W55-M59 HydrophobicContact CZ2-CB 3.92Å; W55-M59 HydrophobicContact CZ2-CG 4.14Å; W55-M59 HydrophobicContact CZ3-CG 4.24Å; W55-M59 CarbonylContact O-C 3.57Å; W55-M59 VanDerWaalsContact O-CA 3.3Å; W55-M59 WeakPolarHBondContact O-CA 3.39Å; W55-M59 WeakPolarHBondContact O-CB 3.08Å; W55-M59 PolarHBondContact O-N 3.24Å; W55-I62 HydrophobicContact CZ2-CB 4.3Å; W55-I62 HydrophobicContact CZ2-CG2 3.94Å; W55-I62 PolarHBondContact NE1-O 3.43Å; W55-P64 HydrophobicContact CZ2-CB 4.43Å; W55-F238 HydrophobicContact CH2-CD2 4.07Å; W55-F238 HydrophobicContact CH2-CE1 4.3Å; W55-F238 AromaticContact CH2-CE2 3.75Å; W55-F238 HydrophobicContact CH2-CE2 3.75Å; W55-F238 HydrophobicContact CH2-CG 4.49Å; W55-F238 AromaticContact CH2-CZ 3.86Å; W55-F238 HydrophobicContact CH2-CZ 3.86Å; W55-F238 HydrophobicContact CZ3-CD1 4.18Å; W55-F238 AromaticContact CZ3-CD2 3.95Å; W55-F238 HydrophobicContact CZ3-CD2 3.95Å; W55-F238 HydrophobicContact CZ3-CE1 4.29Å; W55-F238 HydrophobicContact CZ3-CE2 4.08Å; W55-F238 HydrophobicContact CZ3-CG 4Å; W55-F238 HydrophobicContact CZ3-CZ 4.24Å; W55-L245 HydrophobicContact CE3-CD1 3.88Å; W55-L245 HydrophobicContact CZ3-CD1 3.75Å; W55-A270 HydrophobicContact CH2-CB 3.59Å; W55-A270 HydrophobicContact CZ2-CB 3.65Å; W55-P272 HydrophobicContact CE3-CB 4.33Å; W55-P272 HydrophobicContact CE3-CG 4.27Å; W55-P272 HydrophobicContact CH2-CB 4.24Å; W55-P272 HydrophobicContact CH2-CG 4Å; W55-P272 HydrophobicContact CZ2-CG 4.39Å; W55-P272 HydrophobicContact CZ3-CB 3.83Å; W55-P272 HydrophobicContact CZ3-CG 3.93Å; W55-Y275 HydrophobicContact CB-CE1 4.11Å; W55-Y275 HydrophobicContact CE3-CD1 4.24Å; W55-Y275 AromaticContact CE3-CE1 3.91Å; W55-Y275 HydrophobicContact CE3-CE1 3.91Å; W55-Y275 PolarHBondContact N-OH 3.2Å
56Q95.1Very high94.9Very high104 Ų10436.9 Ų36.949%0.48619%0.194SC..Hα-helixtrans-62.1-36.1178.5-72.1178.1-11.700112.3N52 M53 Q54 A60N52-Q56 PolarHBondContact ND2-NE2 3.04Å; N52-Q56 WeakPolarHBondContact O-CG 3.41Å; N52-Q56 PolarHBondContact O-N 2.86Å; M53-Q56 PolarHBondContact O-N 3.14Å; Q54-Q56 PolarHBondContact O-N 3.34Å; Q56-A60 VanDerWaalsContact O-CA 3.27Å; Q56-A60 WeakPolarHBondContact O-CA 3.22Å; Q56-A60 WeakPolarHBondContact O-CB 3.48Å; Q56-A60 PolarHBondContact O-N 3.26Å
57N95.3Very high95.1Very high136 Ų13637.4 Ų37.473%0.72720%0.197SC*.Hα-helixtrans-69.9-42.2178.6-70.8-23.5000112.6M53 Q54 W55M53-N57 PolarHBondContact O-N 3.41Å; M53-N57 PolarHBondContact O-ND2 2.87Å; Q54-N57 PolarHBondContact O-N 3.25Å; W55-N57 VanDerWaalsContact C-N 3.28Å; W55-N57 PolarHBondContact O-N 3.33Å
58V96.5Very high95.2Very high20 Ų2034.4 Ų34.412%0.12118%0.184CC..Hα-helixtrans-90.8-43.4-174.3-179.20000111.9Q54 W55 L245 E246 N249Q54-V58 PolarHBondContact O-N 2.99Å; W55-V58 PolarHBondContact O-N 2.93Å; V58-L245 HydrophobicContact CB-CD2 3.78Å; V58-L245 HydrophobicContact CB-CG 4.21Å; V58-L245 HydrophobicContact CG1-CD2 4.05Å; V58-L245 HydrophobicContact CG1-CG 3.9Å; V58-L245 HydrophobicContact CG2-CD2 4.05Å; V58-E246 HydrophobicContact CG1-CG 4.4Å; V58-E246 HydrophobicContact CG2-CG 4.37Å; V58-N249 HydrophobicContact CG1-CB 3.7Å; V58-N249 PolarHBondContact O-ND2 3.34Å; V58-N249 PolarHBondContact O-OD1 3.45Å
59M94Very high95.1Very high0 Ų041.5 Ų41.50%022%0.215CC..Hα-helixtrans-111.526.9-170.5-61.5-65.2-131.900112.9W55 P61 I62 F238 L245 V248 N249 I252W55-M59 HydrophobicContact CD2-CB 3.94Å; W55-M59 HydrophobicContact CD2-CG 4.16Å; W55-M59 HydrophobicContact CE3-CB 4.5Å; W55-M59 HydrophobicContact CE3-CG 4.21Å; W55-M59 HydrophobicContact CG-CB 4.26Å; W55-M59 HydrophobicContact CH2-CB 4.48Å; W55-M59 HydrophobicContact CH2-CE 4.32Å; W55-M59 HydrophobicContact CH2-CG 4.21Å; W55-M59 HydrophobicContact CZ2-CB 3.92Å; W55-M59 HydrophobicContact CZ2-CG 4.14Å; W55-M59 HydrophobicContact CZ3-CG 4.24Å; W55-M59 CarbonylContact O-C 3.57Å; W55-M59 VanDerWaalsContact O-CA 3.3Å; W55-M59 WeakPolarHBondContact O-CA 3.39Å; W55-M59 WeakPolarHBondContact O-CB 3.08Å; W55-M59 PolarHBondContact O-N 3.24Å; M59-P61 VanDerWaalsContact C-N 3.34Å; M59-P61 VanDerWaalsContact O-CD 3.3Å; M59-P61 WeakPolarHBondContact O-CD 3.18Å; M59-I62 HydrophobicContact CB-CB 4.39Å; M59-I62 HydrophobicContact CE-CD1 4.43Å; M59-I62 WeakPolarHBondContact O-CA 3.46Å; M59-I62 WeakPolarHBondContact O-CB 3.45Å; M59-I62 PolarHBondContact O-N 3.47Å; M59-I62 HydrophobicContact SD-CD1 3.99Å; M59-F238 HydrophobicContact CE-CD1 4.33Å; M59-F238 HydrophobicContact CE-CE1 3.41Å; M59-F238 VanDerWaalsContact CE-CE1 3.41Å; M59-F238 HydrophobicContact CE-CZ 3.87Å; M59-L245 HydrophobicContact CE-CD1 3.87Å; M59-L245 HydrophobicContact CG-CD1 3.85Å; M59-L245 HydrophobicContact CG-CD2 4.47Å; M59-L245 HydrophobicContact CG-CG 4.2Å; M59-V248 HydrophobicContact CE-CG1 4.34Å; M59-N249 HydrophobicContact CE-CB 4.47Å; M59-N249 HydrophobicContact SD-CB 3.74Å; M59-I252 HydrophobicContact CE-CD1 3.73Å; M59-I252 HydrophobicContact SD-CD1 4.18Å
60A87.1Confident95.1Very high74 Ų7442.1 Ų42.161%0.61222%0.219SC*.THydrogen-bonded Turntrans-38.1-44.5-173.700000117.5Q56 I62Q56-A60 VanDerWaalsContact O-CA 3.27Å; Q56-A60 WeakPolarHBondContact O-CA 3.22Å; Q56-A60 WeakPolarHBondContact O-CB 3.48Å; Q56-A60 PolarHBondContact O-N 3.26Å; A60-I62 VanDerWaalsContact C-N 3.26Å; A60-I62 PolarHBondContact O-N 2.84Å
61P89.8Confident95.1Very high56 Ų5637.8 Ų37.836%0.36420%0.201SC..THydrogen-bonded Turntrans-79.2-5-179.132.6-35.1000114.3M59M59-P61 VanDerWaalsContact C-N 3.34Å; M59-P61 VanDerWaalsContact O-CD 3.3Å; M59-P61 WeakPolarHBondContact O-CD 3.18Å
62I96.6Very high94.9Very high6 Ų638 Ų383%0.03121%0.206CC..EExtended strand (participates in β ladder)trans-106.8115.4-173.2-52.4179.1000109.1W55 M59 A60 I234 I252 L256 V268 A270W55-I62 HydrophobicContact CZ2-CB 4.3Å; W55-I62 HydrophobicContact CZ2-CG2 3.94Å; W55-I62 PolarHBondContact NE1-O 3.43Å; M59-I62 HydrophobicContact CB-CB 4.39Å; M59-I62 HydrophobicContact CE-CD1 4.43Å; M59-I62 WeakPolarHBondContact O-CA 3.46Å; M59-I62 WeakPolarHBondContact O-CB 3.45Å; M59-I62 PolarHBondContact O-N 3.47Å; M59-I62 HydrophobicContact SD-CD1 3.99Å; A60-I62 VanDerWaalsContact C-N 3.26Å; A60-I62 PolarHBondContact O-N 2.84Å; I62-I234 HydrophobicContact CD1-CD1 3.91Å; I62-I234 HydrophobicContact CG2-CD1 4.34Å; I62-I252 HydrophobicContact CD1-CD1 3.74Å; I62-L256 HydrophobicContact CD1-CD1 3.93Å; I62-L256 HydrophobicContact CG1-CD1 4.45Å; I62-V268 WeakPolarHBondContact CA-O 3.48Å; I62-V268 HydrophobicContact CD1-CG1 4.42Å; I62-V268 HydrophobicContact CG1-CB 4.36Å; I62-V268 HydrophobicContact CG1-CG1 4.08Å; I62-V268 HydrophobicContact CG2-CG1 4.19Å; I62-A270 HydrophobicContact CG2-CB 3.72Å
63K97.1Very high94.7Very high79 Ų7937.8 Ų37.834%0.34321%0.205SC..EExtended strand (participates in β ladder)trans-79.4125.6178.6-177.8173.3175.8177.30110.8F65 N107 V268 I269 A270K63-F65 HydrophobicContact CD-CE2 3.87Å; K63-F65 HydrophobicContact CD-CZ 4.48Å; K63-F65 HydrophobicContact CG-CD2 4.36Å; K63-F65 HydrophobicContact CG-CE2 3.96Å; K63-N107 PolarHBondContact NZ-OD1 3.35Å; K63-V268 PolarHBondContact N-O 2.86Å; K63-I269 HydrophobicContact CB-CG2 4.33Å; K63-I269 CarbonylContact O-C 3.6Å; K63-I269 WeakPolarHBondContact O-CA 3.41Å; K63-I269 WeakPolarHBondContact O-CB 3.14Å; K63-A270 PolarHBondContact O-N 3.4Å
64P98.3Very high94.4Very high13 Ų1336.5 Ų36.58%0.08420%0.201CC..EExtended strand (participates in β ladder)trans-77.6140.9176.131.4-33.7000111.9W55 I85 G86 A270 P272 Y276W55-P64 HydrophobicContact CZ2-CB 4.43Å; P64-I85 HydrophobicContact CB-CG2 4.12Å; P64-I85 HydrophobicContact CG-CB 4.46Å; P64-I85 HydrophobicContact CG-CG1 4Å; P64-I85 HydrophobicContact CG-CG2 4.07Å; P64-I85 WeakPolarHBondContact O-CG2 3.45Å; P64-G86 PolarHBondContact O-N 2.66Å; P64-A270 CarbonylContact C-O 3.5Å; P64-P272 HydrophobicContact CB-CG 3.66Å; P64-Y276 HydrophobicContact CB-CE2 4.24Å
65F98.6Very high94Very high6 Ų635.4 Ų35.43%0.02620%0.195CC..EExtended strand (participates in β ladder)trans-123.6102.6169.5-82.1-109.3000109.2K63 P67 G86 N107 I109 I269 A270 E271K63-F65 HydrophobicContact CD-CE2 3.87Å; K63-F65 HydrophobicContact CD-CZ 4.48Å; K63-F65 HydrophobicContact CG-CD2 4.36Å; K63-F65 HydrophobicContact CG-CE2 3.96Å; F65-P67 VanDerWaalsContact O-CD 3.27Å; F65-P67 WeakPolarHBondContact O-CD 3.43Å; F65-G86 CarbonylContact C-O 3.59Å; F65-G86 VanDerWaalsContact CA-O 3.28Å; F65-G86 WeakPolarHBondContact CA-O 2.93Å; F65-N107 WeakPolarHBondContact CE1-O 3.45Å; F65-I109 HydrophobicContact CD1-CD1 3.54Å; F65-I109 HydrophobicContact CD1-CG1 3.72Å; F65-I109 HydrophobicContact CD2-CD1 4.36Å; F65-I109 HydrophobicContact CE1-CD1 3.63Å; F65-I109 HydrophobicContact CE1-CG1 3.67Å; F65-I109 HydrophobicContact CE2-CD1 4.44Å; F65-I109 HydrophobicContact CG-CD1 3.93Å; F65-I109 HydrophobicContact CZ-CD1 4.1Å; F65-I109 HydrophobicContact CZ-CG1 4.48Å; F65-I269 HydrophobicContact CD2-CB 3.97Å; F65-I269 HydrophobicContact CD2-CD1 4.14Å; F65-I269 HydrophobicContact CD2-CG2 4.13Å; F65-I269 HydrophobicContact CE2-CB 4.13Å; F65-I269 HydrophobicContact CE2-CD1 4.3Å; F65-I269 HydrophobicContact CE2-CG2 3.76Å; F65-A270 PolarHBondContact N-O 3.38Å; F65-E271 VanDerWaalsContact O-CA 3.25Å; F65-E271 WeakPolarHBondContact O-CA 3.39Å
66Y98.4Very high93.8Very high0 Ų035.2 Ų35.20%020%0.195CC..EExtended strand (participates in β ladder)trans-66.7122-174.5177.8-107.1000112.5V68 C70 N71 V76 L77 L80 G86 F87 A88 Y276 V277Y66-V68 PolarHBondContact O-N 2.79Å; Y66-C70 HydrophobicContact CE2-CB 4.33Å; Y66-N71 WeakPolarHBondContact CE1-O 3.35Å; Y66-N71 WeakPolarHBondContact OH-CA 3.47Å; Y66-N71 WeakPolarHBondContact OH-CB 3.23Å; Y66-N71 PolarHBondContact OH-N 3.22Å; Y66-N71 PolarHBondContact OH-O 3.14Å; Y66-V76 HydrophobicContact CE1-CG1 4.41Å; Y66-L77 HydrophobicContact CD1-CD2 3.96Å; Y66-L77 HydrophobicContact CE1-CD2 3.81Å; Y66-L80 HydrophobicContact CD1-CD1 3.69Å; Y66-L80 HydrophobicContact CD2-CD1 3.61Å; Y66-L80 HydrophobicContact CE1-CD1 4.04Å; Y66-L80 HydrophobicContact CE2-CD1 3.96Å; Y66-L80 HydrophobicContact CG-CD1 3.46Å; Y66-L80 VanDerWaalsContact CG-CD1 3.46Å; Y66-G86 PolarHBondContact N-O 3.32Å; Y66-F87 HydrophobicContact CD1-CD1 4.05Å; Y66-F87 HydrophobicContact CD1-CE1 4.06Å; Y66-F87 WeakPolarHBondContact O-CA 3.38Å; Y66-A88 PolarHBondContact O-N 2.94Å; Y66-Y276 HydrophobicContact CD2-CD2 4.1Å; Y66-V277 HydrophobicContact CE2-CG1 3.97Å; Y66-V277 HydrophobicContact CE2-CG2 4.39Å; Y66-V277 WeakPolarHBondContact OH-CG1 3.43Å
67P97Very high93.8Very high10 Ų1030.3 Ų30.37%0.06517%0.172CC..EExtended strand (participates in β ladder)trans-67.5108.7170.8-20.434.1000111.8F65 K69 C70 A88 E271 P272F65-P67 VanDerWaalsContact O-CD 3.27Å; F65-P67 WeakPolarHBondContact O-CD 3.43Å; P67-K69 HydrophobicContact CB-CG 4.2Å; P67-K69 PolarHBondContact O-N 2.88Å; P67-K69 VanDerWaalsContact O-N 3.13Å; P67-C70 WeakPolarHBondContact O-CB 3.37Å; P67-C70 PolarHBondContact O-N 3.3Å; P67-A88 WeakPolarHBondContact CA-O 3.32Å; P67-A88 HydrophobicContact CB-CB 4.46Å; P67-A88 HydrophobicContact CG-CB 4.42Å; P67-E271 HydrophobicContact CG-CB 3.99Å; P67-E271 VanDerWaalsContact CG-O 3.24Å; P67-E271 WeakPolarHBondContact CG-O 3.47Å; P67-P272 WeakPolarHBondContact CD-O 3.5Å
68V96.3Very high93.7Very high0 Ų024 Ų240%014%0.138CC..G310 helixtrans-59.9-31.1-175.2-177.80000112.1Y66 C70 N71 S72 L77 F87 A88 E94 V98Y66-V68 PolarHBondContact O-N 2.79Å; V68-C70 PolarHBondContact O-N 3.42Å; V68-C70 VanDerWaalsContact O-N 3.11Å; V68-N71 CarbonylContact O-C 3.6Å; V68-N71 VanDerWaalsContact O-C 3.28Å; V68-N71 PolarHBondContact O-N 3.47Å; V68-S72 PolarHBondContact O-N 2.98Å; V68-L77 HydrophobicContact CG1-CD1 4.19Å; V68-L77 HydrophobicContact CG1-CD2 4.19Å; V68-L77 HydrophobicContact CG2-CD2 4.4Å; V68-F87 HydrophobicContact CG2-CB 4.1Å; V68-F87 HydrophobicContact CG2-CD1 3.83Å; V68-F87 HydrophobicContact CG2-CG 4.39Å; V68-A88 PolarHBondContact N-O 2.6Å; V68-E94 HydrophobicContact CB-CB 4.09Å; V68-E94 HydrophobicContact CB-CG 3.96Å; V68-E94 HydrophobicContact CG1-CB 3.93Å; V68-E94 HydrophobicContact CG1-CG 3.66Å; V68-V98 HydrophobicContact CG2-CG2 3.65Å
69K92.4Very high93.5Very high148 Ų14823.2 Ų23.264%0.64313%0.133SC*.G310 helixtrans-57-23.4176.167.7171.4-175.7170.40114.5P67P67-K69 HydrophobicContact CB-CG 4.2Å; P67-K69 PolarHBondContact O-N 2.88Å; P67-K69 VanDerWaalsContact O-N 3.13Å
70C92.1Very high93.6Very high18 Ų1823.2 Ų23.212%0.12213%0.133CC..G310 helixtrans-70.7-44.1-178.9-72.70000111Y66 P67 V68 V277 S387 G388Y66-C70 HydrophobicContact CE2-CB 4.33Å; P67-C70 WeakPolarHBondContact O-CB 3.37Å; P67-C70 PolarHBondContact O-N 3.3Å; V68-C70 PolarHBondContact O-N 3.42Å; V68-C70 VanDerWaalsContact O-N 3.11Å; C70-V277 HydrophobicContact CB-CG2 4.32Å; C70-S387 CarbonylContact O-C 3.51Å; C70-S387 WeakPolarHBondContact O-CA 3.33Å; C70-G388 PolarHBondContact O-N 2.87Å
71N93.7Very high93.9Very high2 Ų220.1 Ų20.11%0.01111%0.108CC..  trans-160.9106.3174.4-171.2-32.7000108.6Y66 V68 T73 V277 F281 G386 L390Y66-N71 WeakPolarHBondContact CE1-O 3.35Å; Y66-N71 WeakPolarHBondContact OH-CA 3.47Å; Y66-N71 WeakPolarHBondContact OH-CB 3.23Å; Y66-N71 PolarHBondContact OH-N 3.22Å; Y66-N71 PolarHBondContact OH-O 3.14Å; V68-N71 CarbonylContact O-C 3.6Å; V68-N71 VanDerWaalsContact O-C 3.28Å; V68-N71 PolarHBondContact O-N 3.47Å; N71-T73 VanDerWaalsContact C-N 3.29Å; N71-T73 PolarHBondContact O-N 2.93Å; N71-T73 VanDerWaalsContact OD1-CB 3.3Å; N71-T73 WeakPolarHBondContact OD1-CB 3.43Å; N71-T73 WeakPolarHBondContact OD1-CG2 3.25Å; N71-T73 PolarHBondContact OD1-N 3.1Å; N71-T73 PolarHBondContact OD1-OG1 3.39Å; N71-V277 HydrophobicContact CB-CB 4.24Å; N71-V277 HydrophobicContact CB-CG1 4.14Å; N71-V277 HydrophobicContact CB-CG2 4.02Å; N71-F281 WeakPolarHBondContact ND2-CE2 3.44Å; N71-G386 WeakPolarHBondContact CB-O 3.24Å; N71-G386 PolarHBondContact ND2-O 3.47Å; N71-L390 VanDerWaalsContact ND2-CD1 3.31Å; N71-L390 WeakPolarHBondContact ND2-CD1 3.19Å
72S93.3Very high94.1Very high34 Ų3418.3 Ų18.324%0.23810%0.096CC..  trans-92.415.9-178.259.30000112.9V68 L97V68-S72 PolarHBondContact O-N 2.98Å; S72-L97 WeakPolarHBondContact O-CD2 3.32Å
73T90.7Very high93.9Very high2 Ų219.2 Ų19.21%0.01210%0.101CC..  trans-65.7130.5178.459.10000110.1N71 G75 V76 L77 L390 I404 Y406N71-T73 VanDerWaalsContact C-N 3.29Å; N71-T73 PolarHBondContact O-N 2.93Å; N71-T73 VanDerWaalsContact OD1-CB 3.3Å; N71-T73 WeakPolarHBondContact OD1-CB 3.43Å; N71-T73 WeakPolarHBondContact OD1-CG2 3.25Å; N71-T73 PolarHBondContact OD1-N 3.1Å; N71-T73 PolarHBondContact OD1-OG1 3.39Å; T73-G75 VanDerWaalsContact C-N 3.3Å; T73-G75 PolarHBondContact O-N 3.4Å; T73-V76 WeakPolarHBondContact O-CB 3.06Å; T73-V76 PolarHBondContact O-N 3.19Å; T73-V76 VanDerWaalsContact OG1-CG2 3.27Å; T73-V76 WeakPolarHBondContact OG1-CG2 3.37Å; T73-L77 PolarHBondContact O-N 2.84Å; T73-L390 HydrophobicContact CG2-CB 4.34Å; T73-L390 HydrophobicContact CG2-CD1 3.99Å; T73-I404 HydrophobicContact CG2-CD1 3.57Å; T73-Y406 WeakPolarHBondContact CB-OH 3.45Å; T73-Y406 PolarHBondContact OG1-OH 3.27Å
74P86.9Confident93.7Very high32 Ų3217.6 Ų17.621%0.20811%0.107CC..Hα-helixtrans-54.2-40.3-174.2-32.737.7000114.7Y10 V76 L77 E78Y10-P74 HydrophobicContact CE1-CB 4.22Å; Y10-P74 HydrophobicContact CE2-CB 4.26Å; Y10-P74 WeakPolarHBondContact OH-CB 3.36Å; P74-V76 VanDerWaalsContact C-N 3.26Å; P74-V76 PolarHBondContact O-N 2.94Å; P74-L77 PolarHBondContact O-N 3.28Å; P74-E78 WeakPolarHBondContact O-CG 3.47Å; P74-E78 PolarHBondContact O-N 2.96Å
75G88.3Confident93.6Very high0 Ų017.2 Ų17.20%010%0.104CC..Hα-helixtrans-60.5-33.217900000113.7T73 I79T73-G75 VanDerWaalsContact C-N 3.3Å; T73-G75 PolarHBondContact O-N 3.4Å; G75-I79 PolarHBondContact O-N 3.19Å
76V93.6Very high93.6Very high0 Ų016.9 Ų16.90%010%0.103CC..Hα-helixtrans-69.1-48.6172.1171.20000110.1L48 Y66 T73 P74 E78 I79 L80 V277 F281L48-V76 HydrophobicContact CD1-CB 4.43Å; L48-V76 HydrophobicContact CD1-CG1 4.32Å; L48-V76 HydrophobicContact CD1-CG2 4.14Å; Y66-V76 HydrophobicContact CE1-CG1 4.41Å; T73-V76 WeakPolarHBondContact O-CB 3.06Å; T73-V76 PolarHBondContact O-N 3.19Å; T73-V76 VanDerWaalsContact OG1-CG2 3.27Å; T73-V76 WeakPolarHBondContact OG1-CG2 3.37Å; P74-V76 VanDerWaalsContact C-N 3.26Å; P74-V76 PolarHBondContact O-N 2.94Å; V76-E78 PolarHBondContact O-N 2.97Å; V76-I79 PolarHBondContact O-N 2.81Å; V76-L80 HydrophobicContact CG1-CD1 3.66Å; V76-L80 HydrophobicContact CG1-CG 4.19Å; V76-L80 WeakPolarHBondContact O-CB 3.38Å; V76-L80 VanDerWaalsContact O-CG 3.27Å; V76-L80 WeakPolarHBondContact O-CG 3.41Å; V76-L80 PolarHBondContact O-N 3.08Å; V76-V277 HydrophobicContact CG1-CG1 3.69Å; V76-V277 HydrophobicContact CG2-CG1 4.48Å; V76-F281 HydrophobicContact CG2-CE2 3.82Å; V76-F281 HydrophobicContact CG2-CZ 3.61Å
77L94.6Very high93.6Very high0 Ų016.9 Ų16.90%010%0.103CC..Hα-helixtrans-65.1-38.3-176.3-57.8-178.3000112.2Y66 V68 T73 P74 G81 F87 L97 L101Y66-L77 HydrophobicContact CD1-CD2 3.96Å; Y66-L77 HydrophobicContact CE1-CD2 3.81Å; V68-L77 HydrophobicContact CG1-CD1 4.19Å; V68-L77 HydrophobicContact CG1-CD2 4.19Å; V68-L77 HydrophobicContact CG2-CD2 4.4Å; T73-L77 PolarHBondContact O-N 2.84Å; P74-L77 PolarHBondContact O-N 3.28Å; L77-G81 PolarHBondContact O-N 2.92Å; L77-F87 HydrophobicContact CB-CE1 4.22Å; L77-F87 HydrophobicContact CB-CZ 4.48Å; L77-F87 HydrophobicContact CD2-CD1 4.08Å; L77-F87 HydrophobicContact CD2-CE1 3.6Å; L77-F87 HydrophobicContact CG-CE1 4.48Å; L77-F87 WeakPolarHBondContact O-CZ 3.47Å; L77-L97 HydrophobicContact CD1-CD2 3.36Å; L77-L97 HydrophobicContact CD1-CG 3.71Å; L77-L101 HydrophobicContact CB-CD1 3.42Å; L77-L101 VanDerWaalsContact CB-CD1 3.42Å; L77-L101 HydrophobicContact CD1-CD1 4.21Å; L77-L101 HydrophobicContact CG-CD1 4.48Å
78E92.3Very high93.7Very high5 Ų516.5 Ų16.52%0.02310%0.101CC..Hα-helixtrans-64.7-45.1176.4-74-179.9-175.800111.9Y10 P74 V76 G81 T82 L101 N429 F430Y10-E78 WeakPolarHBondContact CE2-OE2 3.31Å; P74-E78 WeakPolarHBondContact O-CG 3.47Å; P74-E78 PolarHBondContact O-N 2.96Å; V76-E78 PolarHBondContact O-N 2.97Å; E78-G81 PolarHBondContact O-N 3.4Å; E78-T82 WeakPolarHBondContact O-CB 3.37Å; E78-T82 PolarHBondContact O-N 2.96Å; E78-T82 PolarHBondContact O-OG1 3.13Å; E78-L101 HydrophobicContact CG-CD1 4.32Å; E78-L101 HydrophobicContact CG-CD2 3.66Å; E78-N429 PolarHBondContact OE1-ND2 3.14Å; E78-F430 HydrophobicContact CB-CE2 3.68Å; E78-F430 HydrophobicContact CB-CZ 3.81Å; E78-F430 VanDerWaalsContact OE2-CE2 3.24Å; E78-F430 WeakPolarHBondContact OE2-CE2 3.48Å
79I92.8Very high93.7Very high2 Ų216.5 Ų16.51%0.0110%0.101CC..Hα-helixtrans-64.7-49.5176.8-75.1175.1000111.1L45 L48 V49 G75 V76 G81 T82 L83 M427 F430L45-I79 HydrophobicContact CB-CD1 3.64Å; L45-I79 HydrophobicContact CD1-CD1 3.66Å; L45-I79 HydrophobicContact CD2-CD1 3.96Å; L45-I79 HydrophobicContact CG-CD1 3.93Å; L48-I79 HydrophobicContact CB-CG2 4.25Å; L48-I79 HydrophobicContact CD1-CG2 4.25Å; V49-I79 HydrophobicContact CG2-CG2 4.31Å; G75-I79 PolarHBondContact O-N 3.19Å; V76-I79 PolarHBondContact O-N 2.81Å; I79-G81 VanDerWaalsContact C-N 3.28Å; I79-G81 PolarHBondContact O-N 3.37Å; I79-T82 WeakPolarHBondContact O-CB 3.26Å; I79-T82 PolarHBondContact O-N 2.8Å; I79-T82 VanDerWaalsContact O-N 3.16Å; I79-L83 HydrophobicContact CG2-CD1 3.91Å; I79-L83 HydrophobicContact CG2-CG 4.46Å; I79-L83 VanDerWaalsContact O-CG 3.28Å; I79-L83 WeakPolarHBondContact O-CG 3.32Å; I79-L83 PolarHBondContact O-N 2.85Å; I79-M427 HydrophobicContact CG1-CE 4.42Å; I79-M427 HydrophobicContact CG1-SD 4.17Å; I79-F430 HydrophobicContact CD1-CE1 4.38Å; I79-F430 HydrophobicContact CD1-CZ 4.1Å; I79-F430 HydrophobicContact CG1-CE2 4.11Å; I79-F430 HydrophobicContact CG1-CZ 3.76Å
80L95.6Very high93.9Very high0 Ų010.6 Ų10.60%08%0.078CC..Hα-helixtrans-62.8-38179.9-63.1178.9000111.4L48 Y66 V76 L83 G84 I85 F87 Y276L48-L80 HydrophobicContact CB-CD2 4.44Å; Y66-L80 HydrophobicContact CD1-CD1 3.69Å; Y66-L80 HydrophobicContact CD2-CD1 3.61Å; Y66-L80 HydrophobicContact CE1-CD1 4.04Å; Y66-L80 HydrophobicContact CE2-CD1 3.96Å; Y66-L80 HydrophobicContact CG-CD1 3.46Å; Y66-L80 VanDerWaalsContact CG-CD1 3.46Å; V76-L80 HydrophobicContact CG1-CD1 3.66Å; V76-L80 HydrophobicContact CG1-CG 4.19Å; V76-L80 WeakPolarHBondContact O-CB 3.38Å; V76-L80 VanDerWaalsContact O-CG 3.27Å; V76-L80 WeakPolarHBondContact O-CG 3.41Å; V76-L80 PolarHBondContact O-N 3.08Å; L80-L83 HydrophobicContact CD2-CD1 4.41Å; L80-L83 PolarHBondContact O-N 3.22Å; L80-G84 PolarHBondContact O-N 2.66Å; L80-I85 HydrophobicContact CB-CB 4.34Å; L80-I85 HydrophobicContact CB-CD1 4.07Å; L80-I85 HydrophobicContact CD2-CD1 3.54Å; L80-I85 HydrophobicContact CG-CD1 4.35Å; L80-I85 VanDerWaalsContact O-CB 3.27Å; L80-I85 WeakPolarHBondContact O-CB 3.17Å; L80-I85 PolarHBondContact O-N 2.9Å; L80-I85 VanDerWaalsContact O-N 3.11Å; L80-F87 HydrophobicContact CB-CE1 4.45Å; L80-F87 HydrophobicContact CB-CZ 4.28Å; L80-Y276 HydrophobicContact CD2-CD1 3.78Å; L80-Y276 HydrophobicContact CD2-CE1 4.15Å; L80-Y276 HydrophobicContact CD2-CG 4.05Å
81G94.8Very high94Very high9 Ų911.8 Ų11.89%0.0938%0.083CC..Hα-helixtrans-62.2-43.1173.900000112.5L77 E78 I79 L83 G84L77-G81 PolarHBondContact O-N 2.92Å; E78-G81 PolarHBondContact O-N 3.4Å; I79-G81 VanDerWaalsContact C-N 3.28Å; I79-G81 PolarHBondContact O-N 3.37Å; G81-L83 VanDerWaalsContact C-N 3.27Å; G81-L83 PolarHBondContact O-N 2.88Å; G81-G84 PolarHBondContact O-N 3.19Å
82T91.9Very high94.1Very high18 Ų1816.6 Ų16.611%0.1110%0.104CC..Hα-helixtrans-63.2-34.6175.3-53.50000111.9E78 I79 G84 I421 D424 L426 M427E78-T82 WeakPolarHBondContact O-CB 3.37Å; E78-T82 PolarHBondContact O-N 2.96Å; E78-T82 PolarHBondContact O-OG1 3.13Å; I79-T82 WeakPolarHBondContact O-CB 3.26Å; I79-T82 PolarHBondContact O-N 2.8Å; I79-T82 VanDerWaalsContact O-N 3.16Å; T82-G84 PolarHBondContact O-N 3.49Å; T82-I421 HydrophobicContact CG2-CB 4.36Å; T82-I421 HydrophobicContact CG2-CG2 3.49Å; T82-I421 VanDerWaalsContact CG2-CG2 3.49Å; T82-I421 WeakPolarHBondContact CG2-O 3.27Å; T82-D424 HydrophobicContact CG2-CB 3.49Å; T82-D424 VanDerWaalsContact CG2-CB 3.49Å; T82-L426 WeakPolarHBondContact OG1-CB 3.38Å; T82-M427 HydrophobicContact CG2-CG 3.93Å; T82-M427 HydrophobicContact CG2-SD 4.35Å
83L92.6Very high94.2Very high25 Ų2518.4 Ų18.413%0.13112%0.117CC..THydrogen-bonded Turntrans-72.50.5174.1-65.5170.2000113.5V49 N52 I79 L80 G81 I85 I421V49-L83 HydrophobicContact CG2-CD1 4.35Å; N52-L83 HydrophobicContact CB-CD1 3.86Å; I79-L83 HydrophobicContact CG2-CD1 3.91Å; I79-L83 HydrophobicContact CG2-CG 4.46Å; I79-L83 VanDerWaalsContact O-CG 3.28Å; I79-L83 WeakPolarHBondContact O-CG 3.32Å; I79-L83 PolarHBondContact O-N 2.85Å; L80-L83 HydrophobicContact CD2-CD1 4.41Å; L80-L83 PolarHBondContact O-N 3.22Å; G81-L83 VanDerWaalsContact C-N 3.27Å; G81-L83 PolarHBondContact O-N 2.88Å; L83-I85 VanDerWaalsContact C-N 3.31Å; L83-I85 HydrophobicContact CB-CD1 4.01Å; L83-I85 HydrophobicContact CB-CG1 4.1Å; L83-I85 HydrophobicContact CD1-CD1 4.33Å; L83-I85 PolarHBondContact O-N 2.83Å; L83-I421 HydrophobicContact CD2-CD1 3.57Å; L83-I421 HydrophobicContact CD2-CG1 4.4Å
84G93.3Very high94.5Very high46 Ų4619.2 Ų19.247%0.47412%0.12SC..THydrogen-bonded Turntrans77.314.3178.700000114.5L80 G81 T82L80-G84 PolarHBondContact O-N 2.66Å; G81-G84 PolarHBondContact O-N 3.19Å; T82-G84 PolarHBondContact O-N 3.49Å
85I96.9Very high94.9Very high4 Ų417.7 Ų17.72%0.02111%0.11CC..  trans-74.5136.7179.2-57.9171.2000108.6N52 P64 L80 L83 Y276N52-I85 HydrophobicContact CB-CD1 4.39Å; P64-I85 HydrophobicContact CB-CG2 4.12Å; P64-I85 HydrophobicContact CG-CB 4.46Å; P64-I85 HydrophobicContact CG-CG1 4Å; P64-I85 HydrophobicContact CG-CG2 4.07Å; P64-I85 WeakPolarHBondContact O-CG2 3.45Å; L80-I85 HydrophobicContact CB-CB 4.34Å; L80-I85 HydrophobicContact CB-CD1 4.07Å; L80-I85 HydrophobicContact CD2-CD1 3.54Å; L80-I85 HydrophobicContact CG-CD1 4.35Å; L80-I85 VanDerWaalsContact O-CB 3.27Å; L80-I85 WeakPolarHBondContact O-CB 3.17Å; L80-I85 PolarHBondContact O-N 2.9Å; L80-I85 VanDerWaalsContact O-N 3.11Å; L83-I85 VanDerWaalsContact C-N 3.31Å; L83-I85 HydrophobicContact CB-CD1 4.01Å; L83-I85 HydrophobicContact CB-CG1 4.1Å; L83-I85 HydrophobicContact CD1-CD1 4.33Å; L83-I85 PolarHBondContact O-N 2.83Å; I85-Y276 HydrophobicContact CD1-CE1 3.84Å; I85-Y276 HydrophobicContact CD1-CE2 4.12Å; I85-Y276 WeakPolarHBondContact CD1-OH 3.3Å
86G98.2Very high95.3Very high0 Ų018.7 Ų18.70%012%0.119CC..EExtended strand (participates in β ladder)trans-76.1176.6173.700000111.8P64 F65 Y66 N107P64-G86 PolarHBondContact O-N 2.66Å; F65-G86 CarbonylContact C-O 3.59Å; F65-G86 VanDerWaalsContact CA-O 3.28Å; F65-G86 WeakPolarHBondContact CA-O 2.93Å; Y66-G86 PolarHBondContact N-O 3.32Å; G86-N107 CarbonylContact C-O 3.59Å; G86-N107 VanDerWaalsContact CA-O 3.3Å; G86-N107 WeakPolarHBondContact CA-O 3.46Å
87F98.5Very high95.3Very high0 Ų020.4 Ų20.40%013%0.127CC..EExtended strand (participates in β ladder)trans-128.5129.9178.7-66.4-86.8000112.3Y66 V68 L77 L80 V98 I103 N107 I108 I109Y66-F87 HydrophobicContact CD1-CD1 4.05Å; Y66-F87 HydrophobicContact CD1-CE1 4.06Å; Y66-F87 WeakPolarHBondContact O-CA 3.38Å; V68-F87 HydrophobicContact CG2-CB 4.1Å; V68-F87 HydrophobicContact CG2-CD1 3.83Å; V68-F87 HydrophobicContact CG2-CG 4.39Å; L77-F87 HydrophobicContact CB-CE1 4.22Å; L77-F87 HydrophobicContact CB-CZ 4.48Å; L77-F87 HydrophobicContact CD2-CD1 4.08Å; L77-F87 HydrophobicContact CD2-CE1 3.6Å; L77-F87 HydrophobicContact CG-CE1 4.48Å; L77-F87 WeakPolarHBondContact O-CZ 3.47Å; L80-F87 HydrophobicContact CB-CE1 4.45Å; L80-F87 HydrophobicContact CB-CZ 4.28Å; F87-V98 HydrophobicContact CB-CG1 3.87Å; F87-V98 HydrophobicContact CB-CG2 3.98Å; F87-V98 HydrophobicContact CD1-CG2 4.01Å; F87-V98 HydrophobicContact CD2-CG1 3.63Å; F87-V98 HydrophobicContact CD2-CG2 4.47Å; F87-V98 HydrophobicContact CE2-CG1 4.33Å; F87-V98 HydrophobicContact CG-CG1 3.77Å; F87-V98 HydrophobicContact CG-CG2 3.88Å; F87-I103 HydrophobicContact CD2-CG1 4.16Å; F87-I103 HydrophobicContact CD2-CG2 3.92Å; F87-I103 HydrophobicContact CE2-CD1 3.92Å; F87-I103 HydrophobicContact CE2-CG1 3.76Å; F87-I103 HydrophobicContact CE2-CG2 4.21Å; F87-N107 PolarHBondContact N-O 3.35Å; F87-I108 WeakPolarHBondContact O-CA 3.38Å; F87-I109 PolarHBondContact O-N 3.29Å
88A98.2Very high95.3Very high2 Ų220.4 Ų20.42%0.01713%0.127CC..EExtended strand (participates in β ladder)trans-95.4109.1169.800000108.8Y66 P67 V68 T111 E271Y66-A88 PolarHBondContact O-N 2.94Å; P67-A88 WeakPolarHBondContact CA-O 3.32Å; P67-A88 HydrophobicContact CB-CB 4.46Å; P67-A88 HydrophobicContact CG-CB 4.42Å; V68-A88 PolarHBondContact N-O 2.6Å; A88-T111 HydrophobicContact CB-CG2 3.82Å; A88-E271 HydrophobicContact CB-CG 4.18Å
89C97.9Very high95.4Very high0 Ų023 Ų230%014%0.14CC..EExtended strand (participates in β ladder)trans-100.7144179.7-64.50000110.8E94 M95 I108 I109 Y110 T111C89-E94 WeakPolarHBondContact CA-OE2 3.34Å; C89-E94 HydrophobicContact CB-CB 4.05Å; C89-M95 HydrophobicContact CB-CG 3.53Å; C89-I108 HydrophobicContact CB-CG2 4.35Å; C89-I109 PolarHBondContact N-O 3.08Å; C89-Y110 CarbonylContact O-C 3.42Å; C89-Y110 WeakPolarHBondContact O-CA 3.47Å; C89-Y110 WeakPolarHBondContact O-CD2 3.42Å; C89-T111 PolarHBondContact O-N 2.92Å; C89-T111 PolarHBondContact O-OG1 2.92Å
90S95.3Very high95.4Very high24 Ų2428.3 Ų28.317%0.16817%0.168CC..  trans-113.2-13.7-178.574.40000113.2E94 N112S90-E94 PolarHBondContact N-OE2 3.26Å; S90-E94 VanDerWaalsContact OG-CD 3.29Å; S90-E94 PolarHBondContact OG-OE1 3.47Å; S90-E94 PolarHBondContact OG-OE2 3.35Å; S90-N112 WeakPolarHBondContact O-CB 3.37Å; S90-N112 PolarHBondContact O-ND2 3.34Å
91N95.3Very high95.1Very high42 Ų4229.7 Ų29.723%0.22518%0.175CC..SBendtrans-151.2174.7-179.663.965.1000111.7S93 E94 M95N91-S93 WeakPolarHBondContact OD1-CA 3.39Å; N91-S93 WeakPolarHBondContact OD1-CB 3.34Å; N91-S93 PolarHBondContact OD1-N 2.94Å; N91-E94 PolarHBondContact ND2-OE1 2.94Å; N91-E94 PolarHBondContact OD1-N 3.07Å; N91-M95 WeakPolarHBondContact O-CG 3.19Å; N91-M95 PolarHBondContact O-N 3.26Å
92K96.1Very high95Very high104 Ų10432.2 Ų32.245%0.45220%0.202SC..Hα-helixtrans-63.7-38.8-179.2175.5-178.2172.3-162.60113.2M95 A96 Q119 Y122K92-M95 PolarHBondContact O-N 2.94Å; K92-A96 WeakPolarHBondContact O-CB 3.4Å; K92-A96 PolarHBondContact O-N 3.24Å; K92-Q119 HydrophobicContact CB-CG 4.13Å; K92-Y122 HydrophobicContact CB-CD1 4.47Å; K92-Y122 HydrophobicContact CD-CD1 4.41Å; K92-Y122 HydrophobicContact CD-CD2 4.2Å; K92-Y122 HydrophobicContact CD-CG 4.09Å; K92-Y122 HydrophobicContact CG-CD1 3.73Å; K92-Y122 HydrophobicContact CG-CD2 4.3Å; K92-Y122 HydrophobicContact CG-CE1 3.91Å; K92-Y122 HydrophobicContact CG-CE2 4.46Å; K92-Y122 HydrophobicContact CG-CG 3.92Å
93S94.7Very high95.1Very high72 Ų7232.3 Ų32.350%0.50320%0.201SC..Hα-helixtrans-65-43.6-177.9-55.70000110.6N91 A96 L97N91-S93 WeakPolarHBondContact OD1-CA 3.39Å; N91-S93 WeakPolarHBondContact OD1-CB 3.34Å; N91-S93 PolarHBondContact OD1-N 2.94Å; S93-A96 PolarHBondContact O-N 3.39Å; S93-L97 WeakPolarHBondContact O-CB 3.4Å; S93-L97 PolarHBondContact O-N 3.5Å
94E96.1Very high95.2Very high18 Ų1833.2 Ų33.28%0.08421%0.21CC..Hα-helixtrans-62.4-45174.9-67.7174.4-167.500112V68 C89 S90 N91 A96 L97 V98V68-E94 HydrophobicContact CB-CB 4.09Å; V68-E94 HydrophobicContact CB-CG 3.96Å; V68-E94 HydrophobicContact CG1-CB 3.93Å; V68-E94 HydrophobicContact CG1-CG 3.66Å; C89-E94 WeakPolarHBondContact CA-OE2 3.34Å; C89-E94 HydrophobicContact CB-CB 4.05Å; S90-E94 PolarHBondContact N-OE2 3.26Å; S90-E94 VanDerWaalsContact OG-CD 3.29Å; S90-E94 PolarHBondContact OG-OE1 3.47Å; S90-E94 PolarHBondContact OG-OE2 3.35Å; N91-E94 PolarHBondContact ND2-OE1 2.94Å; N91-E94 PolarHBondContact OD1-N 3.07Å; E94-A96 VanDerWaalsContact C-N 3.3Å; E94-A96 PolarHBondContact O-N 3.24Å; E94-L97 PolarHBondContact O-N 3.44Å; E94-V98 WeakPolarHBondContact O-CG2 3.26Å; E94-V98 PolarHBondContact O-N 2.91Å
95M97Very high95.3Very high0 Ų032.7 Ų32.70%020%0.198CC..Hα-helixtrans-61.6-38.8176.2-72.9-172.5-75.100112.4C89 N91 K92 Q99 Y110 Y122 A123 I126 I128C89-M95 HydrophobicContact CB-CG 3.53Å; N91-M95 WeakPolarHBondContact O-CG 3.19Å; N91-M95 PolarHBondContact O-N 3.26Å; K92-M95 PolarHBondContact O-N 2.94Å; M95-Q99 VanDerWaalsContact O-CB 3.25Å; M95-Q99 WeakPolarHBondContact O-CB 3.49Å; M95-Q99 PolarHBondContact O-N 3.38Å; M95-Q99 VanDerWaalsContact O-N 3.14Å; M95-Y110 HydrophobicContact CE-CD1 4.34Å; M95-Y110 HydrophobicContact CE-CD2 4.19Å; M95-Y110 HydrophobicContact CE-CE1 4.25Å; M95-Y110 HydrophobicContact CE-CE2 4.13Å; M95-Y110 HydrophobicContact CE-CG 4.33Å; M95-Y110 HydrophobicContact SD-CD1 4.37Å; M95-Y110 HydrophobicContact SD-CD2 4.21Å; M95-Y110 HydrophobicContact SD-CG 4.05Å; M95-Y122 HydrophobicContact CB-CE1 4.08Å; M95-Y122 HydrophobicContact CE-CD1 4.11Å; M95-A123 HydrophobicContact CE-CB 4.33Å; M95-A123 HydrophobicContact SD-CB 3.91Å; M95-I126 HydrophobicContact CB-CD1 4.15Å; M95-I128 HydrophobicContact CB-CD1 3.95Å; M95-I128 HydrophobicContact CG-CD1 3.74Å; M95-I128 HydrophobicContact SD-CD1 3.67Å
96A95.9Very high95.3Very high22 Ų2238.1 Ų38.118%0.18222%0.223CC..Hα-helixtrans-67-46.9176.200000111.2K92 S93 E94 V98 Q99 D100 Y122K92-A96 WeakPolarHBondContact O-CB 3.4Å; K92-A96 PolarHBondContact O-N 3.24Å; S93-A96 PolarHBondContact O-N 3.39Å; E94-A96 VanDerWaalsContact C-N 3.3Å; E94-A96 PolarHBondContact O-N 3.24Å; A96-V98 PolarHBondContact O-N 2.98Å; A96-Q99 PolarHBondContact O-N 3.38Å; A96-D100 WeakPolarHBondContact O-CB 3.44Å; A96-D100 VanDerWaalsContact O-CG 3.23Å; A96-D100 PolarHBondContact O-N 3.09Å; A96-Y122 WeakPolarHBondContact CB-OH 3.34Å
97L93.4Very high95.2Very high35 Ų3540.3 Ų40.318%0.18324%0.235CC..Hα-helixtrans-57.4-51179.2179.163000111.8S72 L77 S93 E94 Q99 D100 L101S72-L97 WeakPolarHBondContact O-CD2 3.32Å; L77-L97 HydrophobicContact CD1-CD2 3.36Å; L77-L97 HydrophobicContact CD1-CG 3.71Å; S93-L97 WeakPolarHBondContact O-CB 3.4Å; S93-L97 PolarHBondContact O-N 3.5Å; E94-L97 PolarHBondContact O-N 3.44Å; L97-Q99 VanDerWaalsContact C-N 3.31Å; L97-Q99 PolarHBondContact O-N 3.21Å; L97-D100 PolarHBondContact O-N 3.33Å; L97-L101 WeakPolarHBondContact O-CG 3.29Å; L97-L101 PolarHBondContact O-N 2.87Å
98V95.2Very high95.2Very high0 Ų040.4 Ų40.40%024%0.235CC..Hα-helixtrans-64.2-37.5179.2172.80000111.6V68 F87 E94 A96 L101 I103 I108V68-V98 HydrophobicContact CG2-CG2 3.65Å; F87-V98 HydrophobicContact CB-CG1 3.87Å; F87-V98 HydrophobicContact CB-CG2 3.98Å; F87-V98 HydrophobicContact CD1-CG2 4.01Å; F87-V98 HydrophobicContact CD2-CG1 3.63Å; F87-V98 HydrophobicContact CD2-CG2 4.47Å; F87-V98 HydrophobicContact CE2-CG1 4.33Å; F87-V98 HydrophobicContact CG-CG1 3.77Å; F87-V98 HydrophobicContact CG-CG2 3.88Å; E94-V98 WeakPolarHBondContact O-CG2 3.26Å; E94-V98 PolarHBondContact O-N 2.91Å; A96-V98 PolarHBondContact O-N 2.98Å; V98-L101 PolarHBondContact O-N 3.35Å; V98-I103 HydrophobicContact CG1-CB 3.63Å; V98-I103 HydrophobicContact CG1-CG1 3.85Å; V98-I103 HydrophobicContact CG1-CG2 3.85Å; V98-I103 WeakPolarHBondContact O-CB 3.45Å; V98-I103 WeakPolarHBondContact O-CG1 3.47Å; V98-I103 PolarHBondContact O-N 3.45Å; V98-I108 HydrophobicContact CB-CD1 4.34Å; V98-I108 HydrophobicContact CG1-CD1 3.61Å; V98-I108 HydrophobicContact CG1-CG1 3.86Å
99Q93.4Very high95.3Very high61 Ų6140.3 Ų40.329%0.28523%0.234SC..Hα-helixtrans-67.5-39.5175.8174.8167.463.200112.6M95 A96 L97 L101 G102 I126M95-Q99 VanDerWaalsContact O-CB 3.25Å; M95-Q99 WeakPolarHBondContact O-CB 3.49Å; M95-Q99 PolarHBondContact O-N 3.38Å; M95-Q99 VanDerWaalsContact O-N 3.14Å; A96-Q99 PolarHBondContact O-N 3.38Å; L97-Q99 VanDerWaalsContact C-N 3.31Å; L97-Q99 PolarHBondContact O-N 3.21Å; Q99-L101 PolarHBondContact O-N 2.65Å; Q99-G102 WeakPolarHBondContact O-CA 2.89Å; Q99-G102 PolarHBondContact O-N 2.75Å; Q99-I126 VanDerWaalsContact OE1-CG2 3.26Å
100D92.4Very high95.3Very high112 Ų11240.3 Ų40.360%0.59923%0.234SC*.Hα-helixtrans-65.9-26.3180-73.2-20.7000111.7L5 A96 L97 G102L5-D100 HydrophobicContact CD1-CB 4.47Å; A96-D100 WeakPolarHBondContact O-CB 3.44Å; A96-D100 VanDerWaalsContact O-CG 3.23Å; A96-D100 PolarHBondContact O-N 3.09Å; L97-D100 PolarHBondContact O-N 3.33Å; D100-G102 PolarHBondContact O-N 3.32Å
101L90.4Very high95.3Very high29 Ų2940.1 Ų40.115%0.15223%0.233CC..THydrogen-bonded Turntrans-70.4-9.5169.1-63177.9000113.2L77 E78 L97 V98 Q99 I103 L426L77-L101 HydrophobicContact CB-CD1 3.42Å; L77-L101 VanDerWaalsContact CB-CD1 3.42Å; L77-L101 HydrophobicContact CD1-CD1 4.21Å; L77-L101 HydrophobicContact CG-CD1 4.48Å; E78-L101 HydrophobicContact CG-CD1 4.32Å; E78-L101 HydrophobicContact CG-CD2 3.66Å; L97-L101 WeakPolarHBondContact O-CG 3.29Å; L97-L101 PolarHBondContact O-N 2.87Å; V98-L101 PolarHBondContact O-N 3.35Å; Q99-L101 PolarHBondContact O-N 2.65Å; L101-I103 HydrophobicContact CB-CG1 4.3Å; L101-L426 WeakPolarHBondContact O-CD2 3.5Å
102G91.5Very high95.2Very high63 Ų6340 Ų4065%0.64923%0.232SC*.THydrogen-bonded Turntrans87.212.6-17900000114.2Q99 D100 S104Q99-G102 WeakPolarHBondContact O-CA 2.89Å; Q99-G102 PolarHBondContact O-N 2.75Å; D100-G102 PolarHBondContact O-N 3.32Å; G102-S104 PolarHBondContact O-N 3.48Å
103I94.1Very high94.8Very high19 Ų1936.6 Ų36.610%0.09722%0.22CC..  trans-68.7131.7175.2-56.4-59.2000110.1F87 V98 L101 N107 I108 L426F87-I103 HydrophobicContact CD2-CG1 4.16Å; F87-I103 HydrophobicContact CD2-CG2 3.92Å; F87-I103 HydrophobicContact CE2-CD1 3.92Å; F87-I103 HydrophobicContact CE2-CG1 3.76Å; F87-I103 HydrophobicContact CE2-CG2 4.21Å; V98-I103 HydrophobicContact CG1-CB 3.63Å; V98-I103 HydrophobicContact CG1-CG1 3.85Å; V98-I103 HydrophobicContact CG1-CG2 3.85Å; V98-I103 WeakPolarHBondContact O-CB 3.45Å; V98-I103 WeakPolarHBondContact O-CG1 3.47Å; V98-I103 PolarHBondContact O-N 3.45Å; L101-I103 HydrophobicContact CB-CG1 4.3Å; I103-N107 HydrophobicContact CG2-CB 4.11Å; I103-I108 HydrophobicContact CG2-CD1 4.44Å; I103-I108 HydrophobicContact CG2-CG1 4.13Å; I103-L426 HydrophobicContact CD1-CD1 4.01Å
104S95.3Very high94.7Very high45 Ų4537.2 Ų37.232%0.31522%0.224SC..  trans-70.3139.9-176.9-1560000112.5G102 E106 N107G102-S104 PolarHBondContact O-N 3.48Å; S104-E106 VanDerWaalsContact CB-CD 3.42Å; S104-E106 WeakPolarHBondContact CB-OE1 3.27Å; S104-E106 PolarHBondContact O-N 2.73Å; S104-E106 VanDerWaalsContact O-N 3.1Å; S104-E106 PolarHBondContact OG-OE1 2.84Å; S104-E106 PolarHBondContact OG-OE2 2.83Å; S104-N107 PolarHBondContact O-N 2.81Å
105P96.3Very high94.7Very high34 Ų3436.4 Ų36.422%0.22122%0.22CC..G310 helixtrans-58.3-25.2-175.7-26.735.2000115.8N107 I108 G127 I128P105-N107 PolarHBondContact O-N 3.44Å; P105-I108 PolarHBondContact O-N 3.19Å; P105-G127 WeakPolarHBondContact CB-O 3.29Å; P105-I128 HydrophobicContact CB-CG1 4.16Å
106E95.9Very high94.7Very high119 Ų11942.2 Ų42.256%0.55625%0.247SC*.G310 helixtrans-68.3-19.317462.1-85.9-170.800114S104 I108S104-E106 VanDerWaalsContact CB-CD 3.42Å; S104-E106 WeakPolarHBondContact CB-OE1 3.27Å; S104-E106 PolarHBondContact O-N 2.73Å; S104-E106 VanDerWaalsContact O-N 3.1Å; S104-E106 PolarHBondContact OG-OE1 2.84Å; S104-E106 PolarHBondContact OG-OE2 2.83Å; E106-I108 VanDerWaalsContact C-N 3.32Å
107N97.3Very high94.7Very high46 Ų4643.2 Ų43.225%0.24626%0.255CS..G310 helixtrans-95.614.9174.3-68.6-42000111.9K63 F65 G86 F87 I103 S104 P105K63-N107 PolarHBondContact NZ-OD1 3.35Å; F65-N107 WeakPolarHBondContact CE1-O 3.45Å; G86-N107 CarbonylContact C-O 3.59Å; G86-N107 VanDerWaalsContact CA-O 3.3Å; G86-N107 WeakPolarHBondContact CA-O 3.46Å; F87-N107 PolarHBondContact N-O 3.35Å; I103-N107 HydrophobicContact CG2-CB 4.11Å; S104-N107 PolarHBondContact O-N 2.81Å; P105-N107 PolarHBondContact O-N 3.44Å
108I98.4Very high94.9Very high1 Ų145 Ų451%0.00527%0.271CS..EExtended strand (participates in β ladder)trans-122132.3178-50.3174.2000110.3F87 C89 V98 I103 P105 E106 I128F87-I108 WeakPolarHBondContact O-CA 3.38Å; C89-I108 HydrophobicContact CB-CG2 4.35Å; V98-I108 HydrophobicContact CB-CD1 4.34Å; V98-I108 HydrophobicContact CG1-CD1 3.61Å; V98-I108 HydrophobicContact CG1-CG1 3.86Å; I103-I108 HydrophobicContact CG2-CD1 4.44Å; I103-I108 HydrophobicContact CG2-CG1 4.13Å; P105-I108 PolarHBondContact O-N 3.19Å; E106-I108 VanDerWaalsContact C-N 3.32Å; I108-I128 HydrophobicContact CB-CD1 4.08Å; I108-I128 HydrophobicContact CB-CG1 4.17Å; I108-I128 HydrophobicContact CB-CG2 4.44Å; I108-I128 HydrophobicContact CD1-CD1 3.98Å; I108-I128 HydrophobicContact CD1-CG1 4.29Å; I108-I128 HydrophobicContact CG2-CD1 3.67Å; I108-I128 HydrophobicContact CG2-CG1 4.27Å; I108-I128 HydrophobicContact CG2-CG2 4.31Å
109I98.4Very high95.1Very high0 Ų046.5 Ų46.50%028%0.278CS..EExtended strand (participates in β ladder)trans-119131.9174.9-56.4174000108.7F65 F87 C89 T111 I130 L152 I269F65-I109 HydrophobicContact CD1-CD1 3.54Å; F65-I109 HydrophobicContact CD1-CG1 3.72Å; F65-I109 HydrophobicContact CD2-CD1 4.36Å; F65-I109 HydrophobicContact CE1-CD1 3.63Å; F65-I109 HydrophobicContact CE1-CG1 3.67Å; F65-I109 HydrophobicContact CE2-CD1 4.44Å; F65-I109 HydrophobicContact CG-CD1 3.93Å; F65-I109 HydrophobicContact CZ-CD1 4.1Å; F65-I109 HydrophobicContact CZ-CG1 4.48Å; F87-I109 PolarHBondContact O-N 3.29Å; C89-I109 PolarHBondContact N-O 3.08Å; I109-T111 HydrophobicContact CB-CG2 4.13Å; I109-T111 HydrophobicContact CG2-CG2 3.63Å; I109-I130 HydrophobicContact CB-CG2 4.5Å; I109-I130 HydrophobicContact CD1-CG2 4.45Å; I109-I130 HydrophobicContact CG1-CB 4.21Å; I109-I130 HydrophobicContact CG1-CG2 3.99Å; I109-I130 HydrophobicContact CG2-CG2 4Å; I109-L152 HydrophobicContact CG2-CD1 4.46Å; I109-I269 HydrophobicContact CD1-CD1 3.15Å
110Y98.3Very high95.3Very high0 Ų043.6 Ų43.60%026%0.264CS..EExtended strand (participates in β ladder)trans-95.3102.6176-176.9-152.1000111.3C89 M95 N112 K115 Q119 I120 A123 I130 M131 T132C89-Y110 CarbonylContact O-C 3.42Å; C89-Y110 WeakPolarHBondContact O-CA 3.47Å; C89-Y110 WeakPolarHBondContact O-CD2 3.42Å; M95-Y110 HydrophobicContact CE-CD1 4.34Å; M95-Y110 HydrophobicContact CE-CD2 4.19Å; M95-Y110 HydrophobicContact CE-CE1 4.25Å; M95-Y110 HydrophobicContact CE-CE2 4.13Å; M95-Y110 HydrophobicContact CE-CG 4.33Å; M95-Y110 HydrophobicContact SD-CD1 4.37Å; M95-Y110 HydrophobicContact SD-CD2 4.21Å; M95-Y110 HydrophobicContact SD-CG 4.05Å; Y110-N112 HydrophobicContact CD2-CB 4.43Å; Y110-N112 HydrophobicContact CE2-CB 3.76Å; Y110-K115 HydrophobicContact CD1-CD 3.42Å; Y110-K115 VanDerWaalsContact CD1-CD 3.42Å; Y110-K115 HydrophobicContact CD1-CG 4.28Å; Y110-K115 HydrophobicContact CE1-CB 3.81Å; Y110-K115 HydrophobicContact CE1-CD 3.13Å; Y110-K115 HydrophobicContact CE1-CG 3.56Å; Y110-K115 HydrophobicContact CE2-CD 4.37Å; Y110-K115 HydrophobicContact CE2-CG 4.32Å; Y110-K115 HydrophobicContact CG-CD 4.15Å; Y110-K115 WeakPolarHBondContact OH-CB 3.3Å; Y110-Q119 HydrophobicContact CE1-CB 4.44Å; Y110-Q119 WeakPolarHBondContact OH-CB 3.22Å; Y110-Q119 PolarHBondContact OH-OE1 3.34Å; Y110-I120 HydrophobicContact CE1-CG1 4.48Å; Y110-A123 HydrophobicContact CD1-CB 4.33Å; Y110-I130 PolarHBondContact N-O 2.82Å; Y110-M131 VanDerWaalsContact O-CA 3.26Å; Y110-M131 WeakPolarHBondContact O-CA 3.36Å; Y110-M131 WeakPolarHBondContact O-CB 3.46Å; Y110-T132 PolarHBondContact O-N 3.02Å; Y110-T132 VanDerWaalsContact O-N 3.08Å
111T95.9Very high95.6Very high21 Ų2144.4 Ų44.413%0.12926%0.262CS..  trans-102.8-7.3-159.860.60000115.2A88 C89 I109 T132 E271A88-T111 HydrophobicContact CB-CG2 3.82Å; C89-T111 PolarHBondContact O-N 2.92Å; C89-T111 PolarHBondContact O-OG1 2.92Å; I109-T111 HydrophobicContact CB-CG2 4.13Å; I109-T111 HydrophobicContact CG2-CG2 3.63Å; T111-T132 VanDerWaalsContact C-OG1 3.22Å; T111-T132 WeakPolarHBondContact CA-OG1 3.32Å; T111-T132 HydrophobicContact CG2-CG2 4.33Å; T111-T132 PolarHBondContact O-OG1 2.69Å; T111-E271 WeakPolarHBondContact CG2-OE1 3.43Å
112N93.2Very high96Very high39 Ų3945 Ų4521%0.20926%0.263CS..  trans-60.1127.3-176.2-175.3-28.6000111.9S90 Y110 C114 K115S90-N112 WeakPolarHBondContact O-CB 3.37Å; S90-N112 PolarHBondContact O-ND2 3.34Å; Y110-N112 HydrophobicContact CD2-CB 4.43Å; Y110-N112 HydrophobicContact CE2-CB 3.76Å; N112-C114 VanDerWaalsContact C-N 3.27Å; N112-C114 PolarHBondContact O-N 2.66Å; N112-C114 PolarHBondContact OD1-N 3.18Å; N112-C114 PolarHBondContact OD1-O 3.36Å; N112-K115 HydrophobicContact CB-CG 4.25Å; N112-K115 VanDerWaalsContact O-CG 3.22Å; N112-K115 WeakPolarHBondContact O-CG 3.04Å; N112-K115 PolarHBondContact O-NZ 3.06Å
113P87.3Confident96.3Very high32 Ų3242 Ų4221%0.20823%0.232CC..SBendtrans-63.8-29.9-179.824.6-33.7000113.5F170P113-F170 HydrophobicContact CB-CD1 3.55Å; P113-F170 HydrophobicContact CB-CE1 3.8Å; P113-F170 HydrophobicContact CB-CG 4.28Å; P113-F170 HydrophobicContact CG-CD1 3.59Å; P113-F170 HydrophobicContact CG-CE1 3.37Å; P113-F170 HydrophobicContact CG-CE2 4.47Å; P113-F170 HydrophobicContact CG-CG 4.25Å; P113-F170 HydrophobicContact CG-CZ 3.86Å
114C92.4Very high96.5Very high85 Ų8542.6 Ų42.657%0.57424%0.24SC*.SBendtrans-122.780.5-172.6-66.80000111.2N112N112-C114 VanDerWaalsContact C-N 3.27Å; N112-C114 PolarHBondContact O-N 2.66Å; N112-C114 PolarHBondContact OD1-N 3.18Å; N112-C114 PolarHBondContact OD1-O 3.36Å
115K96.2Very high96.6Very high2 Ų249 Ų491%0.00926%0.262CS..  trans-85.8136.4-172.1-47.1175.6-118.4-710111.3Y110 N112 I120 T132 E138 K141Y110-K115 HydrophobicContact CD1-CD 3.42Å; Y110-K115 VanDerWaalsContact CD1-CD 3.42Å; Y110-K115 HydrophobicContact CD1-CG 4.28Å; Y110-K115 HydrophobicContact CE1-CB 3.81Å; Y110-K115 HydrophobicContact CE1-CD 3.13Å; Y110-K115 HydrophobicContact CE1-CG 3.56Å; Y110-K115 HydrophobicContact CE2-CD 4.37Å; Y110-K115 HydrophobicContact CE2-CG 4.32Å; Y110-K115 HydrophobicContact CG-CD 4.15Å; Y110-K115 WeakPolarHBondContact OH-CB 3.3Å; N112-K115 HydrophobicContact CB-CG 4.25Å; N112-K115 VanDerWaalsContact O-CG 3.22Å; N112-K115 WeakPolarHBondContact O-CG 3.04Å; N112-K115 PolarHBondContact O-NZ 3.06Å; K115-I120 HydrophobicContact CB-CD1 3.97Å; K115-I120 HydrophobicContact CB-CG1 3.72Å; K115-I120 HydrophobicContact CD-CG1 4.32Å; K115-T132 WeakPolarHBondContact CE-O 3.4Å; K115-T132 PolarHBondContact NZ-O 2.83Å; K115-T132 PolarHBondContact NZ-OG1 3.47Å; K115-E138 WeakPolarHBondContact CA-OE1 3.47Å; K115-E138 WeakPolarHBondContact CB-OE1 3.48Å; K115-E138 WeakPolarHBondContact CG-OE1 3.34Å; K115-E138 PolarHBondContact N-OE1 3.42Å; K115-K141 PolarHBondContact O-NZ 3.25Å
116Q96.9Very high96.6Very high121 Ų12148.3 Ų48.357%0.56526%0.256SS*.  trans-76.6141.4170.5-63-175.614.700109.9S118 Q119 I120Q116-S118 PolarHBondContact O-N 3.46Å; Q116-S118 VanDerWaalsContact O-N 3.14Å; Q116-Q119 HydrophobicContact CB-CG 4.11Å; Q116-Q119 WeakPolarHBondContact O-CA 3.37Å; Q116-Q119 WeakPolarHBondContact O-CB 3.37Å; Q116-Q119 PolarHBondContact O-N 2.97Å; Q116-I120 PolarHBondContact O-N 3.14Å
117A97.1Very high96.7Very high43 Ų4344 Ų4436%0.35524%0.244SC..Hα-helixtrans-58-32.6-179.500000112.9Q119 I120 K121A117-Q119 VanDerWaalsContact C-N 3.35Å; A117-I120 PolarHBondContact O-N 2.93Å; A117-K121 WeakPolarHBondContact O-CB 3.3Å; A117-K121 VanDerWaalsContact O-CG 3.29Å; A117-K121 WeakPolarHBondContact O-CG 3.44Å; A117-K121 PolarHBondContact O-N 2.81Å
118S97.6Very high96.7Very high74 Ų7441.8 Ų41.852%0.51723%0.232SC..Hα-helixtrans-62.4-38.9173.254.20000112.7Q116 Y122Q116-S118 PolarHBondContact O-N 3.46Å; Q116-S118 VanDerWaalsContact O-N 3.14Å; S118-Y122 PolarHBondContact O-N 3.33Å
119Q98.1Very high96.7Very high30 Ų3044.4 Ų44.414%0.1425%0.246CC..Hα-helixtrans-75-37.6178.1-60.1-175.613.300111.4K92 Y110 Q116 A117 Y122 A123K92-Q119 HydrophobicContact CB-CG 4.13Å; Y110-Q119 HydrophobicContact CE1-CB 4.44Å; Y110-Q119 WeakPolarHBondContact OH-CB 3.22Å; Y110-Q119 PolarHBondContact OH-OE1 3.34Å; Q116-Q119 HydrophobicContact CB-CG 4.11Å; Q116-Q119 WeakPolarHBondContact O-CA 3.37Å; Q116-Q119 WeakPolarHBondContact O-CB 3.37Å; Q116-Q119 PolarHBondContact O-N 2.97Å; A117-Q119 VanDerWaalsContact C-N 3.35Å; Q119-Y122 WeakPolarHBondContact O-CB 3.29Å; Q119-Y122 PolarHBondContact O-N 3.18Å; Q119-A123 PolarHBondContact O-N 2.83Å
120I98.4Very high96.7Very high0 Ų045.3 Ų45.30%025%0.251CS..Hα-helixtrans-61.5-46.1172.6-59.2169000110.6Y110 K115 Q116 A117 Y122 A123 A124 K141 I142 H146Y110-I120 HydrophobicContact CE1-CG1 4.48Å; K115-I120 HydrophobicContact CB-CD1 3.97Å; K115-I120 HydrophobicContact CB-CG1 3.72Å; K115-I120 HydrophobicContact CD-CG1 4.32Å; Q116-I120 PolarHBondContact O-N 3.14Å; A117-I120 PolarHBondContact O-N 2.93Å; I120-Y122 VanDerWaalsContact C-N 3.25Å; I120-Y122 PolarHBondContact O-N 3.46Å; I120-A123 PolarHBondContact O-N 3Å; I120-A124 PolarHBondContact O-N 3.21Å; I120-K141 HydrophobicContact CD1-CB 3.98Å; I120-I142 HydrophobicContact CD1-CG1 3.94Å; I120-H146 HydrophobicContact CG2-CB 3.74Å
121K98.3Very high96.7Very high129 Ų12945.3 Ų45.356%0.56125%0.251SS*.Hα-helixtrans-61.5-35.5175.3-73.5177.1-177.9-177.60112.2A117 K125A117-K121 WeakPolarHBondContact O-CB 3.3Å; A117-K121 VanDerWaalsContact O-CG 3.29Å; A117-K121 WeakPolarHBondContact O-CG 3.44Å; A117-K121 PolarHBondContact O-N 2.81Å; K121-K125 WeakPolarHBondContact O-CB 3.25Å; K121-K125 PolarHBondContact O-N 3.08Å
122Y98.3Very high96.8Very high41 Ų4144.4 Ų44.416%0.16125%0.245CC..Hα-helixtrans-64.5-51.3174.2-179.5-97.2000111.1K92 M95 A96 S118 Q119 I120 A124 K125 I126K92-Y122 HydrophobicContact CB-CD1 4.47Å; K92-Y122 HydrophobicContact CD-CD1 4.41Å; K92-Y122 HydrophobicContact CD-CD2 4.2Å; K92-Y122 HydrophobicContact CD-CG 4.09Å; K92-Y122 HydrophobicContact CG-CD1 3.73Å; K92-Y122 HydrophobicContact CG-CD2 4.3Å; K92-Y122 HydrophobicContact CG-CE1 3.91Å; K92-Y122 HydrophobicContact CG-CE2 4.46Å; K92-Y122 HydrophobicContact CG-CG 3.92Å; M95-Y122 HydrophobicContact CB-CE1 4.08Å; M95-Y122 HydrophobicContact CE-CD1 4.11Å; A96-Y122 WeakPolarHBondContact CB-OH 3.34Å; S118-Y122 PolarHBondContact O-N 3.33Å; Q119-Y122 WeakPolarHBondContact O-CB 3.29Å; Q119-Y122 PolarHBondContact O-N 3.18Å; I120-Y122 VanDerWaalsContact C-N 3.25Å; I120-Y122 PolarHBondContact O-N 3.46Å; Y122-A124 VanDerWaalsContact C-N 3.26Å; Y122-A124 PolarHBondContact O-N 2.66Å; Y122-K125 WeakPolarHBondContact O-CA 3.35Å; Y122-K125 WeakPolarHBondContact O-CB 3.46Å; Y122-K125 PolarHBondContact O-N 2.89Å; Y122-I126 HydrophobicContact CD1-CD1 4.02Å; Y122-I126 HydrophobicContact CD1-CG1 4.34Å; Y122-I126 HydrophobicContact CE1-CD1 3.44Å; Y122-I126 VanDerWaalsContact CE1-CD1 3.44Å; Y122-I126 HydrophobicContact CE1-CG1 4.13Å; Y122-I126 HydrophobicContact CE1-CG2 4.2Å; Y122-I126 HydrophobicContact CE2-CG2 4.03Å; Y122-I126 WeakPolarHBondContact O-CG1 3.14Å; Y122-I126 PolarHBondContact O-N 2.96Å
123A98.2Very high97Very high0 Ų042.7 Ų42.70%024%0.236CC..Hα-helixtrans-53.1-44.5175.600000111.7M95 Y110 Q119 I120 K125 I126 G127 I128M95-A123 HydrophobicContact CE-CB 4.33Å; M95-A123 HydrophobicContact SD-CB 3.91Å; Y110-A123 HydrophobicContact CD1-CB 4.33Å; Q119-A123 PolarHBondContact O-N 2.83Å; I120-A123 PolarHBondContact O-N 3Å; A123-K125 PolarHBondContact O-N 3.02Å; A123-I126 WeakPolarHBondContact O-CG1 3.41Å; A123-I126 PolarHBondContact O-N 3.19Å; A123-G127 PolarHBondContact O-N 2.83Å; A123-I128 HydrophobicContact CB-CB 4.24Å; A123-I128 PolarHBondContact O-N 3.14Å
124A98.1Very high97.4Very high32 Ų3242.1 Ų42.126%0.26423%0.231SC..Hα-helixtrans-59.5-45.6174.300000113I120 Y122 I126 G127 H146I120-A124 PolarHBondContact O-N 3.21Å; Y122-A124 VanDerWaalsContact C-N 3.26Å; Y122-A124 PolarHBondContact O-N 2.66Å; A124-I126 VanDerWaalsContact C-N 3.28Å; A124-I126 PolarHBondContact O-N 3.18Å; A124-G127 PolarHBondContact O-N 3.04Å; A124-H146 WeakPolarHBondContact CA-NE2 3.33Å; A124-H146 HydrophobicContact CB-CB 3.82Å; A124-H146 VanDerWaalsContact CB-CG 3.44Å
125K97.7Very high97.5Very high179 Ų17940.2 Ų40.278%0.77822%0.215SC*.Hα-helixtrans-61-37.5179.6-178.5-174.1175.8-171.40112.1K121 Y122 A123K121-K125 WeakPolarHBondContact O-CB 3.25Å; K121-K125 PolarHBondContact O-N 3.08Å; Y122-K125 WeakPolarHBondContact O-CA 3.35Å; Y122-K125 WeakPolarHBondContact O-CB 3.46Å; Y122-K125 PolarHBondContact O-N 2.89Å; A123-K125 PolarHBondContact O-N 3.02Å
126I96.8Very high97.5Very high21 Ų2142.6 Ų42.611%0.10823%0.228CC..Hα-helixtrans-94.42.7-176.867.5162.2000113.5M95 Q99 Y122 A123 A124 I128M95-I126 HydrophobicContact CB-CD1 4.15Å; Q99-I126 VanDerWaalsContact OE1-CG2 3.26Å; Y122-I126 HydrophobicContact CD1-CD1 4.02Å; Y122-I126 HydrophobicContact CD1-CG1 4.34Å; Y122-I126 HydrophobicContact CE1-CD1 3.44Å; Y122-I126 VanDerWaalsContact CE1-CD1 3.44Å; Y122-I126 HydrophobicContact CE1-CG1 4.13Å; Y122-I126 HydrophobicContact CE1-CG2 4.2Å; Y122-I126 HydrophobicContact CE2-CG2 4.03Å; Y122-I126 WeakPolarHBondContact O-CG1 3.14Å; Y122-I126 PolarHBondContact O-N 2.96Å; A123-I126 WeakPolarHBondContact O-CG1 3.41Å; A123-I126 PolarHBondContact O-N 3.19Å; A124-I126 VanDerWaalsContact C-N 3.28Å; A124-I126 PolarHBondContact O-N 3.18Å; I126-I128 HydrophobicContact CD1-CD1 3.37Å; I126-I128 HydrophobicContact CD1-CG1 3.93Å; I126-I128 HydrophobicContact CG1-CD1 3.97Å; I126-I128 HydrophobicContact CG1-CG1 4.01Å
127G97.3Very high97.4Very high28 Ų2840.6 Ų40.629%0.28922%0.224SC..THydrogen-bonded Turntrans83.110.6173.800000115.5P105 A123 A124 N129P105-G127 WeakPolarHBondContact CB-O 3.29Å; A123-G127 PolarHBondContact O-N 2.83Å; A124-G127 PolarHBondContact O-N 3.04Å; G127-N129 PolarHBondContact O-N 3.26Å; G127-N129 PolarHBondContact O-ND2 3.42Å; G127-N129 VanDerWaalsContact O-ND2 3.16Å
128I98.1Very high97.4Very high0 Ų038.7 Ų38.70%021%0.208CC..  trans-76.1111173.7-63.2173.4000108.1M95 P105 I108 A123 I126 H146M95-I128 HydrophobicContact CB-CD1 3.95Å; M95-I128 HydrophobicContact CG-CD1 3.74Å; M95-I128 HydrophobicContact SD-CD1 3.67Å; P105-I128 HydrophobicContact CB-CG1 4.16Å; I108-I128 HydrophobicContact CB-CD1 4.08Å; I108-I128 HydrophobicContact CB-CG1 4.17Å; I108-I128 HydrophobicContact CB-CG2 4.44Å; I108-I128 HydrophobicContact CD1-CD1 3.98Å; I108-I128 HydrophobicContact CD1-CG1 4.29Å; I108-I128 HydrophobicContact CG2-CD1 3.67Å; I108-I128 HydrophobicContact CG2-CG1 4.27Å; I108-I128 HydrophobicContact CG2-CG2 4.31Å; A123-I128 HydrophobicContact CB-CB 4.24Å; A123-I128 PolarHBondContact O-N 3.14Å; I126-I128 HydrophobicContact CD1-CD1 3.37Å; I126-I128 HydrophobicContact CD1-CG1 3.93Å; I126-I128 HydrophobicContact CG1-CD1 3.97Å; I126-I128 HydrophobicContact CG1-CG1 4.01Å; I128-H146 PolarHBondContact O-CD2 3.11Å; I128-H146 PolarHBondContact O-NE2 2.74Å
129N98.3Very high97.3Very high55 Ų5535.3 Ų35.329%0.29418%0.184SC..  trans-102.8-30.6-173.1-61.3-47000113.1G127 H146 A149 K150G127-N129 PolarHBondContact O-N 3.26Å; G127-N129 PolarHBondContact O-ND2 3.42Å; G127-N129 VanDerWaalsContact O-ND2 3.16Å; N129-H146 PolarHBondContact OD1-CE1 3.18Å; N129-H146 PolarHBondContact OD1-NE2 2.79Å; N129-A149 CarbonylContact O-C 3.59Å; N129-A149 WeakPolarHBondContact O-CA 3.42Å; N129-K150 PolarHBondContact O-N 3.1Å
130I98.4Very high97.3Very high20 Ų2037.5 Ų37.510%0.10319%0.193CC..EExtended strand (participates in β ladder)trans-82.9124.1-175.6-50174.7000109.1I109 Y110 K150 L152 M231I109-I130 HydrophobicContact CB-CG2 4.5Å; I109-I130 HydrophobicContact CD1-CG2 4.45Å; I109-I130 HydrophobicContact CG1-CB 4.21Å; I109-I130 HydrophobicContact CG1-CG2 3.99Å; I109-I130 HydrophobicContact CG2-CG2 4Å; Y110-I130 PolarHBondContact N-O 2.82Å; I130-K150 WeakPolarHBondContact CA-O 3.2Å; I130-L152 HydrophobicContact CG2-CD1 4.09Å; I130-L152 HydrophobicContact CG2-CG 4.12Å; I130-M231 HydrophobicContact CD1-CE 4.02Å; I130-M231 HydrophobicContact CD1-SD 4.31Å; I130-M231 HydrophobicContact CG2-SD 4.13Å
131M98.3Very high97.2Very high0 Ų040.4 Ų40.40%021%0.206CC..EExtended strand (participates in β ladder)trans-150.1156.6177.564.3-175.77200112.5Y110 I142 H146 A149 K150 L151 L152Y110-M131 VanDerWaalsContact O-CA 3.26Å; Y110-M131 WeakPolarHBondContact O-CA 3.36Å; Y110-M131 WeakPolarHBondContact O-CB 3.46Å; M131-I142 HydrophobicContact CG-CD1 4.29Å; M131-I142 HydrophobicContact SD-CB 4.37Å; M131-I142 HydrophobicContact SD-CD1 3.66Å; M131-I142 HydrophobicContact SD-CG1 3.73Å; M131-I142 HydrophobicContact SD-CG2 3.7Å; M131-H146 HydrophobicContact CE-CB 4.45Å; M131-H146 WeakPolarHBondContact CE-CD2 3.46Å; M131-A149 HydrophobicContact CE-CB 3.74Å; M131-A149 HydrophobicContact CG-CB 4.39Å; M131-A149 HydrophobicContact SD-CB 3.99Å; M131-K150 PolarHBondContact N-O 2.94Å; M131-L151 HydrophobicContact CG-CD2 3.42Å; M131-L151 VanDerWaalsContact CG-CD2 3.42Å; M131-L151 CarbonylContact O-C 3.56Å; M131-L151 WeakPolarHBondContact O-CA 3.47Å; M131-L151 HydrophobicContact SD-CD2 4.13Å; M131-L152 PolarHBondContact O-N 2.72Å
132T97.9Very high97.2Very high2 Ų234.3 Ų34.31%0.01218%0.179CC..EExtended strand (participates in β ladder)trans-84.7156.8179.358.70000112Y110 T111 K115 L152 K195Y110-T132 PolarHBondContact O-N 3.02Å; Y110-T132 VanDerWaalsContact O-N 3.08Å; T111-T132 VanDerWaalsContact C-OG1 3.22Å; T111-T132 WeakPolarHBondContact CA-OG1 3.32Å; T111-T132 HydrophobicContact CG2-CG2 4.33Å; T111-T132 PolarHBondContact O-OG1 2.69Å; K115-T132 WeakPolarHBondContact CE-O 3.4Å; K115-T132 PolarHBondContact NZ-O 2.83Å; K115-T132 PolarHBondContact NZ-OG1 3.47Å; T132-L152 CarbonylContact C-O 3.52Å; T132-L152 VanDerWaalsContact CA-O 3.32Å; T132-L152 WeakPolarHBondContact CA-O 3.44Å; T132-K195 HydrophobicContact CG2-CD 3.43Å; T132-K195 VanDerWaalsContact CG2-CD 3.43Å
133C97.2Very high97.1Very high3 Ų333.3 Ų33.32%0.0218%0.179CC..EExtended strand (participates in β ladder)trans-155.3135.4172.3-175.20000110.4N135 I142 L151 L152 L153 H154C133-N135 PolarHBondContact SG-O 3.05Å; C133-I142 HydrophobicContact CB-CD1 4.33Å; C133-L151 HydrophobicContact CB-CD1 4.15Å; C133-L151 HydrophobicContact CB-CD2 4.47Å; C133-L152 PolarHBondContact N-O 3.2Å; C133-L153 WeakPolarHBondContact O-CA 3.46Å; C133-H154 PolarHBondContact O-N 3.13Å
134D96Very high97.1Very high20 Ų2043.3 Ų43.311%0.10722%0.217CC..  trans-128.3-2.6177.358.97.7000114.3H154 G171 T172D134-H154 HydrophobicContact CB-CB 4.18Å; D134-G171 PolarHBondContact OD2-N 3.27Å; D134-T172 HydrophobicContact CB-CG2 4.46Å; D134-T172 VanDerWaalsContact O-CB 3.32Å; D134-T172 WeakPolarHBondContact O-CB 3.44Å
135N95.1Very high97.1Very high45 Ų4542.8 Ų42.824%0.24121%0.212CC..SBendtrans-145.8160.3-177.36981.7000113.5C133 T137 E138 L139 L180C133-N135 PolarHBondContact SG-O 3.05Å; N135-T137 VanDerWaalsContact C-N 3.3Å; N135-T137 PolarHBondContact O-N 2.83Å; N135-T137 WeakPolarHBondContact OD1-CB 3.48Å; N135-T137 PolarHBondContact OD1-N 2.91Å; N135-E138 PolarHBondContact O-N 3.45Å; N135-E138 WeakPolarHBondContact OD1-CB 3.22Å; N135-E138 PolarHBondContact OD1-N 3.45Å; N135-L139 PolarHBondContact O-N 3.41Å; N135-L139 VanDerWaalsContact O-N 3.09Å; N135-L180 VanDerWaalsContact C-CD2 3.49Å
136D94.8Very high97.1Very high52 Ų5234.5 Ų34.528%0.27818%0.176SC..Hα-helixtrans-66.7-33.7-174.576.3-66000112.1L139 K140 L180D136-L139 PolarHBondContact O-N 3.37Å; D136-K140 WeakPolarHBondContact O-CB 3.39Å; D136-K140 WeakPolarHBondContact O-CD 3.43Å; D136-K140 VanDerWaalsContact O-CG 3.26Å; D136-K140 WeakPolarHBondContact O-CG 3.47Å; D136-K140 PolarHBondContact O-N 3.11Å; D136-K140 IonicContact OD2-NZ 2.72Å; D136-K140 PolarHBondContact OD2-NZ 3.05Å; D136-L180 HydrophobicContact CB-CD2 4.3Å
137T95.7Very high97Very high78 Ų7837.6 Ų37.648%0.47920%0.197SC..Hα-helixtrans-69.2-40.8-179.1-64.30000110.4N135 K140 K141N135-T137 VanDerWaalsContact C-N 3.3Å; N135-T137 PolarHBondContact O-N 2.83Å; N135-T137 WeakPolarHBondContact OD1-CB 3.48Å; N135-T137 PolarHBondContact OD1-N 2.91Å; T137-K140 PolarHBondContact O-N 3.23Å; T137-K141 WeakPolarHBondContact O-CG 3.46Å; T137-K141 PolarHBondContact O-N 2.75Å
138E96.4Very high97Very high4 Ų442.1 Ų42.12%0.01922%0.215CC..Hα-helixtrans-63-48173.6-157.164-145.700111.1K115 N135 K140 K141 I142K115-E138 WeakPolarHBondContact CA-OE1 3.47Å; K115-E138 WeakPolarHBondContact CB-OE1 3.48Å; K115-E138 WeakPolarHBondContact CG-OE1 3.34Å; K115-E138 PolarHBondContact N-OE1 3.42Å; N135-E138 PolarHBondContact O-N 3.45Å; N135-E138 WeakPolarHBondContact OD1-CB 3.22Å; N135-E138 PolarHBondContact OD1-N 3.45Å; E138-K140 VanDerWaalsContact C-N 3.33Å; E138-K140 PolarHBondContact O-N 2.87Å; E138-K141 WeakPolarHBondContact O-CB 2.95Å; E138-K141 PolarHBondContact O-N 3Å; E138-K141 VanDerWaalsContact O-N 3.08Å; E138-K141 IonicContact OE1-NZ 2.89Å; E138-K141 PolarHBondContact OE1-NZ 3.16Å; E138-K141 WeakPolarHBondContact OE2-CE 3.46Å; E138-K141 IonicContact OE2-NZ 2.61Å; E138-K141 PolarHBondContact OE2-NZ 2.99Å; E138-I142 HydrophobicContact CG-CD1 4.09Å; E138-I142 WeakPolarHBondContact O-CG1 3.37Å; E138-I142 PolarHBondContact O-N 3.2Å
139L96.8Very high96.9Very high2 Ų242.1 Ų42.11%0.0122%0.215CC..Hα-helixtrans-56.2-45.6176.5179.261.5000112N135 D136 K141 I142 A143 L151 L180 C183 A184 F187 I189N135-L139 PolarHBondContact O-N 3.41Å; N135-L139 VanDerWaalsContact O-N 3.09Å; D136-L139 PolarHBondContact O-N 3.37Å; L139-K141 PolarHBondContact O-N 3.25Å; L139-I142 PolarHBondContact O-N 2.77Å; L139-A143 WeakPolarHBondContact O-CB 3.27Å; L139-A143 PolarHBondContact O-N 3.49Å; L139-L151 HydrophobicContact CD1-CD1 3.44Å; L139-L151 VanDerWaalsContact CD1-CD1 3.44Å; L139-L180 HydrophobicContact CD2-CD2 4.41Å; L139-L180 WeakPolarHBondContact CD2-O 3.41Å; L139-C183 HydrophobicContact CD2-CB 3.56Å; L139-A184 HydrophobicContact CD1-CB 4.17Å; L139-A184 HydrophobicContact CD2-CB 4.19Å; L139-F187 HydrophobicContact CD2-CD2 4.32Å; L139-F187 HydrophobicContact CD2-CE2 4.49Å; L139-F187 HydrophobicContact CG-CD2 4.11Å; L139-F187 HydrophobicContact CG-CE2 4.43Å; L139-I189 HydrophobicContact CD1-CB 4.5Å; L139-I189 HydrophobicContact CD1-CG2 4.34Å
140K96.8Very high97Very high77 Ų7743.6 Ų43.634%0.33522%0.219SC..Hα-helixtrans-62.3-39.6175.9-73.7164.1-175.1160.10112.4D136 T137 E138 R144 F187D136-K140 WeakPolarHBondContact O-CB 3.39Å; D136-K140 WeakPolarHBondContact O-CD 3.43Å; D136-K140 VanDerWaalsContact O-CG 3.26Å; D136-K140 WeakPolarHBondContact O-CG 3.47Å; D136-K140 PolarHBondContact O-N 3.11Å; D136-K140 IonicContact OD2-NZ 2.72Å; D136-K140 PolarHBondContact OD2-NZ 3.05Å; T137-K140 PolarHBondContact O-N 3.23Å; E138-K140 VanDerWaalsContact C-N 3.33Å; E138-K140 PolarHBondContact O-N 2.87Å; K140-R144 VanDerWaalsContact O-CG 3.3Å; K140-R144 WeakPolarHBondContact O-CG 3.37Å; K140-R144 PolarHBondContact O-N 3.04Å; K140-F187 HydrophobicContact CG-CE2 3.72Å; K140-F187 HydrophobicContact CG-CZ 3.82Å
141K97.1Very high96.9Very high61 Ų6142.7 Ų42.727%0.26521%0.214SC..Hα-helixtrans-64.8-43.7176-75.8-176.8-62.4175.40111.3K115 I120 T137 E138 L139 S145K115-K141 PolarHBondContact O-NZ 3.25Å; I120-K141 HydrophobicContact CD1-CB 3.98Å; T137-K141 WeakPolarHBondContact O-CG 3.46Å; T137-K141 PolarHBondContact O-N 2.75Å; E138-K141 WeakPolarHBondContact O-CB 2.95Å; E138-K141 PolarHBondContact O-N 3Å; E138-K141 VanDerWaalsContact O-N 3.08Å; E138-K141 IonicContact OE1-NZ 2.89Å; E138-K141 PolarHBondContact OE1-NZ 3.16Å; E138-K141 WeakPolarHBondContact OE2-CE 3.46Å; E138-K141 IonicContact OE2-NZ 2.61Å; E138-K141 PolarHBondContact OE2-NZ 2.99Å; L139-K141 PolarHBondContact O-N 3.25Å; K141-S145 VanDerWaalsContact O-CB 3.27Å; K141-S145 WeakPolarHBondContact O-CB 3.3Å; K141-S145 PolarHBondContact O-N 3.28Å; K141-S145 PolarHBondContact O-OG 3.27Å
142I97.7Very high97Very high0 Ų042.7 Ų42.70%021%0.214CC..Hα-helixtrans-65.2-49.7179.1-64.5164000110.2I120 M131 C133 E138 L139 R144 S145 H146 A149 L151I120-I142 HydrophobicContact CD1-CG1 3.94Å; M131-I142 HydrophobicContact CG-CD1 4.29Å; M131-I142 HydrophobicContact SD-CB 4.37Å; M131-I142 HydrophobicContact SD-CD1 3.66Å; M131-I142 HydrophobicContact SD-CG1 3.73Å; M131-I142 HydrophobicContact SD-CG2 3.7Å; C133-I142 HydrophobicContact CB-CD1 4.33Å; E138-I142 HydrophobicContact CG-CD1 4.09Å; E138-I142 WeakPolarHBondContact O-CG1 3.37Å; E138-I142 PolarHBondContact O-N 3.2Å; L139-I142 PolarHBondContact O-N 2.77Å; I142-R144 PolarHBondContact O-N 2.73Å; I142-R144 VanDerWaalsContact O-N 3.12Å; I142-S145 PolarHBondContact O-N 3.16Å; I142-H146 CarbonylContact O-C 2.99Å; I142-H146 PolarHBondContact O-N 2.91Å; I142-A149 HydrophobicContact CG2-CB 3.53Å; I142-L151 HydrophobicContact CD1-CD2 3.89Å; I142-L151 HydrophobicContact CG2-CD2 4.16Å
143A97.2Very high97Very high20 Ų2042.7 Ų42.717%0.16521%0.214CC..Hα-helixtrans-52.7-38.9179.300000113.4L139 F187 I189L139-A143 WeakPolarHBondContact O-CB 3.27Å; L139-A143 PolarHBondContact O-N 3.49Å; A143-F187 HydrophobicContact CB-CB 3.81Å; A143-F187 HydrophobicContact CB-CD2 4.2Å; A143-F187 HydrophobicContact CB-CG 4.03Å; A143-I189 HydrophobicContact CB-CD1 4.24Å; A143-I189 HydrophobicContact CB-CG1 3.84Å
144R97Very high97Very high210 Ų21043.6 Ų43.679%0.79222%0.218SC*.Hα-helixtrans-77.5-27.1178.8-67.9172-177.1175.41.2114K140 I142K140-R144 VanDerWaalsContact O-CG 3.3Å; K140-R144 WeakPolarHBondContact O-CG 3.37Å; K140-R144 PolarHBondContact O-N 3.04Å; I142-R144 PolarHBondContact O-N 2.73Å; I142-R144 VanDerWaalsContact O-N 3.12Å
145S97.8Very high97Very high22 Ų2242.7 Ų42.715%0.15421%0.213CC..Hα-helixtrans-111-25.8-165.5-55.70000113.9K141 I142K141-S145 VanDerWaalsContact O-CB 3.27Å; K141-S145 WeakPolarHBondContact O-CB 3.3Å; K141-S145 PolarHBondContact O-N 3.28Å; K141-S145 PolarHBondContact O-OG 3.27Å; I142-S145 PolarHBondContact O-N 3.16Å
146H98Very high97Very high4 Ų442.4 Ų42.42%0.01922%0.217CC..  trans-147.680.8-179.3-168.6-3.6000111I120 A124 I128 N129 M131 I142 N148 A149I120-H146 HydrophobicContact CG2-CB 3.74Å; A124-H146 WeakPolarHBondContact CA-NE2 3.33Å; A124-H146 HydrophobicContact CB-CB 3.82Å; A124-H146 VanDerWaalsContact CB-CG 3.44Å; I128-H146 PolarHBondContact O-CD2 3.11Å; I128-H146 PolarHBondContact O-NE2 2.74Å; N129-H146 PolarHBondContact OD1-CE1 3.18Å; N129-H146 PolarHBondContact OD1-NE2 2.79Å; M131-H146 HydrophobicContact CE-CB 4.45Å; M131-H146 WeakPolarHBondContact CE-CD2 3.46Å; I142-H146 CarbonylContact O-C 2.99Å; I142-H146 PolarHBondContact O-N 2.91Å; H146-N148 PolarHBondContact ND1-N 3.04Å; H146-N148 PolarHBondContact O-N 3.05Å; H146-A149 HydrophobicContact CB-CB 4.28Å; H146-A149 VanDerWaalsContact O-CB 3.24Å; H146-A149 WeakPolarHBondContact O-CB 3.28Å; H146-A149 PolarHBondContact O-N 3.03Å; H146-A149 VanDerWaalsContact O-N 3.13Å
147P95.1Very high96.6Very high86 Ų8641.3 Ų41.356%0.55821%0.212SC*.THydrogen-bonded Turntrans-63.9-19.6-177.4-2435.3000114.8A149P147-A149 VanDerWaalsContact C-N 3.33Å
148N96.6Very high95.4Very high123 Ų12344.3 Ų44.366%0.65822%0.221SC*.THydrogen-bonded Turntrans-92.66.9179.4-62.5-31.1000112.7H146H146-N148 PolarHBondContact ND1-N 3.04Å; H146-N148 PolarHBondContact O-N 3.05Å
149A97.9Very high93.8Very high0 Ų045.3 Ų45.30%023%0.226CC..  trans-60.9142.5178.500000111.6N129 M131 I142 H146 P147 L151N129-A149 CarbonylContact O-C 3.59Å; N129-A149 WeakPolarHBondContact O-CA 3.42Å; M131-A149 HydrophobicContact CE-CB 3.74Å; M131-A149 HydrophobicContact CG-CB 4.39Å; M131-A149 HydrophobicContact SD-CB 3.99Å; I142-A149 HydrophobicContact CG2-CB 3.53Å; H146-A149 HydrophobicContact CB-CB 4.28Å; H146-A149 VanDerWaalsContact O-CB 3.24Å; H146-A149 WeakPolarHBondContact O-CB 3.28Å; H146-A149 PolarHBondContact O-N 3.03Å; H146-A149 VanDerWaalsContact O-N 3.13Å; P147-A149 VanDerWaalsContact C-N 3.33Å; A149-L151 HydrophobicContact CB-CD2 4.21Å
150K98.4Very high91.6Very high87 Ų8750.3 Ų50.338%0.37825%0.252SS..EExtended strand (participates in β ladder)trans-113.8112.6173.5-68.5-179.6178.8179.80107.7N129 I130 M131 V192N129-K150 PolarHBondContact O-N 3.1Å; I130-K150 WeakPolarHBondContact CA-O 3.2Å; M131-K150 PolarHBondContact N-O 2.94Å; K150-V192 HydrophobicContact CB-CB 4.47Å; K150-V192 HydrophobicContact CB-CG1 3.78Å; K150-V192 HydrophobicContact CB-CG2 3.82Å; K150-V192 HydrophobicContact CD-CG1 4.19Å; K150-V192 HydrophobicContact CG-CG1 3.94Å
151L98.3Very high89.3Confident0 Ų048.1 Ų48.10%025%0.246CC..EExtended strand (participates in β ladder)trans-93.4135.7-170-58.5-172.1000112.8M131 C133 L139 I142 A149 I189 Q190 I191 V192 G193M131-L151 HydrophobicContact CG-CD2 3.42Å; M131-L151 VanDerWaalsContact CG-CD2 3.42Å; M131-L151 CarbonylContact O-C 3.56Å; M131-L151 WeakPolarHBondContact O-CA 3.47Å; M131-L151 HydrophobicContact SD-CD2 4.13Å; C133-L151 HydrophobicContact CB-CD1 4.15Å; C133-L151 HydrophobicContact CB-CD2 4.47Å; L139-L151 HydrophobicContact CD1-CD1 3.44Å; L139-L151 VanDerWaalsContact CD1-CD1 3.44Å; I142-L151 HydrophobicContact CD1-CD2 3.89Å; I142-L151 HydrophobicContact CG2-CD2 4.16Å; A149-L151 HydrophobicContact CB-CD2 4.21Å; L151-I189 HydrophobicContact CD1-CG2 3.55Å; L151-I189 HydrophobicContact CG-CG2 3.74Å; L151-Q190 PolarHBondContact N-O 2.69Å; L151-I191 HydrophobicContact CB-CG1 4.38Å; L151-V192 PolarHBondContact O-N 2.6Å; L151-G193 PolarHBondContact O-N 3.3Å
152L98.6Very high86.7Confident0 Ų050.4 Ų50.40%028%0.276CS..EExtended strand (participates in β ladder)trans-98117.3159.5-55.4-179000108.2I109 I130 M131 T132 C133 H154 V192 G193 K195 M231 D233I109-L152 HydrophobicContact CG2-CD1 4.46Å; I130-L152 HydrophobicContact CG2-CD1 4.09Å; I130-L152 HydrophobicContact CG2-CG 4.12Å; M131-L152 PolarHBondContact O-N 2.72Å; T132-L152 CarbonylContact C-O 3.52Å; T132-L152 VanDerWaalsContact CA-O 3.32Å; T132-L152 WeakPolarHBondContact CA-O 3.44Å; C133-L152 PolarHBondContact N-O 3.2Å; L152-H154 PolarHBondContact O-N 3.14Å; L152-V192 HydrophobicContact CD2-CG2 3.92Å; L152-G193 WeakPolarHBondContact CA-O 3.22Å; L152-K195 HydrophobicContact CB-CB 4.26Å; L152-M231 HydrophobicContact CD1-CG 4.44Å; L152-M231 HydrophobicContact CD1-SD 4.03Å; L152-M231 HydrophobicContact CD2-CB 3.91Å; L152-M231 HydrophobicContact CD2-CG 3.85Å; L152-M231 HydrophobicContact CD2-SD 3.92Å; L152-M231 HydrophobicContact CG-SD 4.49Å; L152-D233 HydrophobicContact CD1-CB 4.23Å
153L98.2Very high84.2Confident2 Ų254.6 Ų54.61%0.0130%0.299CS..EExtended strand (participates in β ladder)trans-72119.4173.8-67.1-174.7000109.2C133 I155 C177 L180 M181 I191 G193 V194 K195 V218C133-L153 WeakPolarHBondContact O-CA 3.46Å; L153-I155 PolarHBondContact O-N 3.06Å; L153-C177 HydrophobicContact CD1-CB 4.33Å; L153-L180 HydrophobicContact CD2-CB 4.26Å; L153-L180 HydrophobicContact CD2-CD1 4.15Å; L153-M181 HydrophobicContact CD1-CE 3.64Å; L153-M181 HydrophobicContact CD1-CG 4.1Å; L153-I191 HydrophobicContact CD1-CD1 4.18Å; L153-I191 HydrophobicContact CD1-CG2 4.22Å; L153-I191 HydrophobicContact CD2-CD1 4.24Å; L153-I191 HydrophobicContact CG-CD1 4.34Å; L153-I191 HydrophobicContact CG-CG2 3.9Å; L153-G193 PolarHBondContact N-O 2.87Å; L153-V194 CarbonylContact O-C 3.34Å; L153-V194 WeakPolarHBondContact O-CA 3.41Å; L153-K195 PolarHBondContact O-N 3.48Å; L153-V218 HydrophobicContact CD1-CG1 4.2Å
154H97.7Very high81.6Confident22 Ų2259.4 Ų59.410%0.10232%0.318CS..EExtended strand (participates in β ladder)trans-87.2108.5179.5-179.7-159.6000109.6C133 D134 L152 G171 T172 K195C133-H154 PolarHBondContact O-N 3.13Å; D134-H154 HydrophobicContact CB-CB 4.18Å; L152-H154 PolarHBondContact O-N 3.14Å; H154-G171 CarbonylContact O-C 3.5Å; H154-G171 WeakPolarHBondContact O-CA 3.2Å; H154-T172 WeakPolarHBondContact O-CG2 3.41Å; H154-T172 PolarHBondContact O-N 3.04Å; H154-K195 CarbonylContact C-O 3.54Å; H154-K195 VanDerWaalsContact CA-O 3.29Å; H154-K195 WeakPolarHBondContact CA-O 3.37Å; H154-K195 HydrophobicContact CB-CB 4.37Å; H154-K195 PolarHBondContact CD2-O 2.75Å
155I96.8Very high79Confident2 Ų258.8 Ų58.81%0.0132%0.324CS..BIsolated β-bridgetrans-88.5146.7178.961.9172.7000111.1L153 T172 V194 K195 F196 D214 A215 V218L153-I155 PolarHBondContact O-N 3.06Å; I155-T172 WeakPolarHBondContact CA-O 3.27Å; I155-V194 HydrophobicContact CD1-CG1 3.89Å; I155-V194 HydrophobicContact CG1-CG1 3.91Å; I155-V194 HydrophobicContact CG2-CG1 3.97Å; I155-K195 WeakPolarHBondContact CG1-O 3.42Å; I155-K195 PolarHBondContact N-O 3.02Å; I155-F196 HydrophobicContact CD1-CB 4.32Å; I155-F196 HydrophobicContact CG1-CB 3.77Å; I155-D214 HydrophobicContact CD1-CB 3.81Å; I155-A215 HydrophobicContact CD1-CB 4.18Å; I155-V218 HydrophobicContact CG2-CG2 4.04Å
156A93.4Very high76.3Confident39 Ų3966.3 Ų66.332%0.32236%0.359SS..  trans-72.1145.7175.700000110.7T172A156-T172 PolarHBondContact N-O 3.37Å
157T86.7Confident74Confident29 Ų2970.4 Ų70.418%0.17838%0.381CS..  trans-111.5147.5171.3580000110.3D159 F196 H197 V198 A211T157-D159 WeakPolarHBondContact CB-OD1 3.25Å; T157-D159 PolarHBondContact O-N 3.01Å; T157-D159 VanDerWaalsContact O-N 3.08Å; T157-D159 PolarHBondContact OG1-OD1 3.13Å; T157-F196 HydrophobicContact CG2-CB 3.83Å; T157-F196 HydrophobicContact CG2-CD2 4.33Å; T157-F196 HydrophobicContact CG2-CG 4.45Å; T157-H197 PolarHBondContact OG1-O 2.9Å; T157-V198 HydrophobicContact CG2-CG2 4.26Å; T157-A211 HydrophobicContact CG2-CB 3.92Å
158E71.9Confident72.3Confident141 Ų14173.9 Ų73.966%0.65939%0.392SS*.  trans-82.573.1170-65.1-177.3171.100109I160 T207E158-I160 PolarHBondContact O-N 2.91Å; E158-I160 VanDerWaalsContact O-N 3.12Å; E158-T207 WeakPolarHBondContact O-CG2 3.24Å; E158-T207 PolarHBondContact O-OG1 2.68Å
159D61.4Low71Confident25 Ų2574.4 Ų74.413%0.13439%0.388CS..  trans-74.898.2170.5-77.721.7000107.9T157 S161 S199 T207T157-D159 WeakPolarHBondContact CB-OD1 3.25Å; T157-D159 PolarHBondContact O-N 3.01Å; T157-D159 VanDerWaalsContact O-N 3.08Å; T157-D159 PolarHBondContact OG1-OD1 3.13Å; D159-S161 PolarHBondContact O-N 2.77Å; D159-S199 WeakPolarHBondContact OD2-CB 3.42Å; D159-S199 PolarHBondContact OD2-N 3.29Å; D159-T207 WeakPolarHBondContact OD1-CG2 3.17Å
160I50.7Low70.4Confident107 Ų10778.9 Ų78.955%0.54941%0.408SS..  trans-78.468.6171.9-50.6176000107.8E158E158-I160 PolarHBondContact O-N 2.91Å; E158-I160 VanDerWaalsContact O-N 3.12Å
161S48.9Very low70Confident31 Ų3175.9 Ų75.922%0.21740%0.401CS..  trans-87131.3167.966.70000109.1D159 D163 E164D159-S161 PolarHBondContact O-N 2.77Å; S161-D163 PolarHBondContact O-N 3Å; S161-E164 VanDerWaalsContact O-CG 3.3Å; S161-E164 WeakPolarHBondContact O-CG 3.44Å; S161-E164 PolarHBondContact O-N 2.85Å
162A41.9Very low69.8Low109 Ų10976.2 Ų76.290%0.90140%0.404SS*.SBendtrans-60.2-6.6-178.200000115.6
163D46.2Very low69.6Low87 Ų8780.5 Ų80.547%0.46543%0.43SS..  trans-109.559.8175.1-71-42.2000110.5S161 E165 K332S161-D163 PolarHBondContact O-N 3Å; D163-E165 PolarHBondContact O-N 2.85Å; D163-E165 VanDerWaalsContact O-N 3.17Å; D163-K332 IonicContact OD1-NZ 3.14Å; D163-K332 PolarHBondContact OD1-NZ 3.45Å; D163-K332 IonicContact OD2-NZ 3.6Å; D163-K332 PolarHBondContact OD2-NZ 3.22Å
164E43.3Very low69.4Low122 Ų12283 Ų8357%0.5744%0.443SS*.THydrogen-bonded Turntrans-65.5-12.6-178-69.1-155.4114.700114.6S161 K169S161-E164 VanDerWaalsContact O-CG 3.3Å; S161-E164 WeakPolarHBondContact O-CG 3.44Å; S161-E164 PolarHBondContact O-N 2.85Å; E164-K169 IonicContact OE1-NZ 3.38Å; E164-K169 PolarHBondContact OE1-NZ 2.96Å
165E41.8Very low69.2Low196 Ų19690.8 Ų90.892%0.91648%0.476SS*.THydrogen-bonded Turntrans-82.6-13.7-170.8-73-174158.100115.2D163D163-E165 PolarHBondContact O-N 2.85Å; D163-E165 VanDerWaalsContact O-N 3.17Å
166M40.6Very low69.2Low181 Ų18193.3 Ų93.389%0.89249%0.49SS*.THydrogen-bonded Turntrans-124.1-8.5-174.6-76.4-162172.300116.8
167N50.1Low69.3Low90 Ų9091.5 Ų91.548%0.48148%0.475SS..  trans-91.3118.4-177.8-73.5-31.7000112K169N167-K169 PolarHBondContact O-N 2.95Å; N167-K169 VanDerWaalsContact O-N 3.08Å
168M59.7Low69.8Low159 Ų15995.7 Ų95.778%0.78349%0.487SS*.  trans-61.8110.1168-85.2-171.6156.900109.7F170M168-F170 HydrophobicContact CB-CE2 4.01Å; M168-F170 HydrophobicContact CB-CZ 3.99Å; M168-F170 HydrophobicContact SD-CZ 4.19Å
169K69.3Low71Confident134 Ų13492.7 Ų92.758%0.58347%0.473SS*.  trans-79.6124.4173.3-62.6-173.3-178.7-177.10109E164 N167E164-K169 IonicContact OE1-NZ 3.38Å; E164-K169 PolarHBondContact OE1-NZ 2.96Å; N167-K169 PolarHBondContact O-N 2.95Å; N167-K169 VanDerWaalsContact O-N 3.08Å
170F84.5Confident72.7Confident93 Ų9391.5 Ų91.541%0.40847%0.467SS..  trans-106.3165.9174.4-64.3-73000110.5P113 M168P113-F170 HydrophobicContact CB-CD1 3.55Å; P113-F170 HydrophobicContact CB-CE1 3.8Å; P113-F170 HydrophobicContact CB-CG 4.28Å; P113-F170 HydrophobicContact CG-CD1 3.59Å; P113-F170 HydrophobicContact CG-CE1 3.37Å; P113-F170 HydrophobicContact CG-CE2 4.47Å; P113-F170 HydrophobicContact CG-CG 4.25Å; P113-F170 HydrophobicContact CG-CZ 3.86Å; M168-F170 HydrophobicContact CB-CE2 4.01Å; M168-F170 HydrophobicContact CB-CZ 3.99Å; M168-F170 HydrophobicContact SD-CZ 4.19Å
171G89.8Confident74.9Confident24 Ų2486.4 Ų86.425%0.24744%0.441CS..  trans101.4165.417600000114.1D134 H154D134-G171 PolarHBondContact OD2-N 3.27Å; H154-G171 CarbonylContact O-C 3.5Å; H154-G171 WeakPolarHBondContact O-CA 3.2Å
172T93.8Very high77.2Confident8 Ų888.8 Ų88.85%0.04945%0.448CS..BIsolated β-bridgetrans-109.9150.9-176.6176.40000112.2D134 H154 I155 A156 N176 C177 L180D134-T172 HydrophobicContact CB-CG2 4.46Å; D134-T172 VanDerWaalsContact O-CB 3.32Å; D134-T172 WeakPolarHBondContact O-CB 3.44Å; H154-T172 WeakPolarHBondContact O-CG2 3.41Å; H154-T172 PolarHBondContact O-N 3.04Å; I155-T172 WeakPolarHBondContact CA-O 3.27Å; A156-T172 PolarHBondContact N-O 3.37Å; T172-N176 VanDerWaalsContact OG1-CB 3.26Å; T172-N176 WeakPolarHBondContact OG1-CB 3.34Å; T172-N176 PolarHBondContact OG1-ND2 3.4Å; T172-C177 WeakPolarHBondContact CG2-SG 3.36Å; T172-L180 HydrophobicContact CG2-CD1 3.92Å
173T95.3Very high79.8Confident90 Ų9084.1 Ų84.155%0.55241%0.409SS*.  trans-69.6156.8170.564.70000111.3K175 N176 C177T173-K175 VanDerWaalsContact C-N 3.28Å; T173-K175 PolarHBondContact O-N 3.32Å; T173-N176 PolarHBondContact O-N 3.17Å; T173-N176 VanDerWaalsContact O-N 3.09Å; T173-N176 WeakPolarHBondContact OG1-CB 3.43Å; T173-N176 PolarHBondContact OG1-N 3.02Å; T173-C177 PolarHBondContact O-N 3.39Å; T173-C177 PolarHBondContact O-SG 2.98Å
174L94.4Very high82.2Confident54 Ų5480 Ų8028%0.28339%0.387SS..Hα-helixtrans-54.5-42.4174.4-67.7-179.8000112.7N176 C177 R178 D214 V218L174-N176 VanDerWaalsContact C-N 3.31Å; L174-N176 PolarHBondContact O-N 2.98Å; L174-C177 WeakPolarHBondContact O-CB 3.23Å; L174-C177 PolarHBondContact O-N 3.32Å; L174-R178 PolarHBondContact O-N 2.81Å; L174-D214 HydrophobicContact CD1-CB 4.46Å; L174-D214 HydrophobicContact CD2-CB 3.96Å; L174-V218 HydrophobicContact CD2-CG2 3.47Å; L174-V218 VanDerWaalsContact CD2-CG2 3.47Å
175K93.4Very high84.7Confident185 Ų18580 Ų8080%0.80439%0.385SS*.Hα-helixtrans-58.5-44.3177-178.6-178.1175.8-1760111.5T173 R178T173-K175 VanDerWaalsContact C-N 3.28Å; T173-K175 PolarHBondContact O-N 3.32Å; K175-R178 PolarHBondContact O-N 2.91Å
176N95.3Very high87.3Confident56 Ų5677.9 Ų77.930%0.29938%0.375SS..Hα-helixtrans-76.9-24.7-179.2-173.666.8000112.3T172 T173 L174 R178 H179 L180T172-N176 VanDerWaalsContact OG1-CB 3.26Å; T172-N176 WeakPolarHBondContact OG1-CB 3.34Å; T172-N176 PolarHBondContact OG1-ND2 3.4Å; T173-N176 PolarHBondContact O-N 3.17Å; T173-N176 VanDerWaalsContact O-N 3.09Å; T173-N176 WeakPolarHBondContact OG1-CB 3.43Å; T173-N176 PolarHBondContact OG1-N 3.02Å; L174-N176 VanDerWaalsContact C-N 3.31Å; L174-N176 PolarHBondContact O-N 2.98Å; N176-R178 VanDerWaalsContact C-N 3.28Å; N176-R178 PolarHBondContact O-N 3.18Å; N176-H179 WeakPolarHBondContact O-CB 3.24Å; N176-H179 PolarHBondContact O-N 2.83Å; N176-H179 VanDerWaalsContact O-N 3.14Å; N176-L180 WeakPolarHBondContact O-CG 3.45Å; N176-L180 PolarHBondContact O-N 3.39Å
177C96.9Very high89.9Confident0 Ų073.4 Ų73.40%035%0.351CS..Hα-helixtrans-55.7-42.9170.1-66.80000112.1L153 T172 T173 L174 H179 L180 M181 V218 M221L153-C177 HydrophobicContact CD1-CB 4.33Å; T172-C177 WeakPolarHBondContact CG2-SG 3.36Å; T173-C177 PolarHBondContact O-N 3.39Å; T173-C177 PolarHBondContact O-SG 2.98Å; L174-C177 WeakPolarHBondContact O-CB 3.23Å; L174-C177 PolarHBondContact O-N 3.32Å; C177-H179 VanDerWaalsContact C-N 3.32Å; C177-H179 PolarHBondContact O-N 3.2Å; C177-L180 PolarHBondContact O-N 3.22Å; C177-M181 WeakPolarHBondContact O-CG 3.26Å; C177-M181 PolarHBondContact O-N 3.13Å; C177-V218 HydrophobicContact CB-CG1 4.46Å; C177-V218 HydrophobicContact CB-CG2 4.27Å; C177-M221 HydrophobicContact CB-CE 4.37Å
178R96.2Very high92.1Very high118 Ų11872 Ų7245%0.44536%0.358SS..Hα-helixtrans-58.8-45.3176.3-166.4177.3-142.7-160.66.5111.8L174 K175 N176 L180 M181 E182 M221 E224 F225L174-R178 PolarHBondContact O-N 2.81Å; K175-R178 PolarHBondContact O-N 2.91Å; N176-R178 VanDerWaalsContact C-N 3.28Å; N176-R178 PolarHBondContact O-N 3.18Å; R178-L180 PolarHBondContact O-N 3.06Å; R178-M181 WeakPolarHBondContact O-CB 3.46Å; R178-M181 PolarHBondContact O-N 3.39Å; R178-E182 WeakPolarHBondContact O-CG 3.39Å; R178-E182 PolarHBondContact O-N 3.08Å; R178-E182 VanDerWaalsContact O-N 3.07Å; R178-M221 HydrophobicContact CB-SD 4.21Å; R178-E224 IonicContact NH2-OE2 3.85Å; R178-E224 PolarHBondContact NH2-OE2 2.96Å; R178-F225 HydrophobicContact CG-CE2 3.93Å; R178-F225 HydrophobicContact CG-CZ 4.01Å
179H96.7Very high93.8Very high78 Ų7864.7 Ų64.736%0.36132%0.322SS..Hα-helixtrans-62.2-41.7176.5179.455.4000112.2N176 C177 M181 E182 C183N176-H179 WeakPolarHBondContact O-CB 3.24Å; N176-H179 PolarHBondContact O-N 2.83Å; N176-H179 VanDerWaalsContact O-N 3.14Å; C177-H179 VanDerWaalsContact C-N 3.32Å; C177-H179 PolarHBondContact O-N 3.2Å; H179-M181 VanDerWaalsContact C-N 3.3Å; H179-M181 PolarHBondContact O-N 2.83Å; H179-E182 IonicContact ND1-OE2 3.84Å; H179-E182 WeakPolarHBondContact O-CB 3.34Å; H179-E182 PolarHBondContact O-N 2.88Å; H179-C183 VanDerWaalsContact CE1-SG 3.54Å; H179-C183 PolarHBondContact O-N 3.19Å
180L97.4Very high95.2Very high0 Ų063.6 Ų63.60%032%0.319CS..Hα-helixtrans-62.8-37176.2-66.3176.4000112.3N135 D136 L139 L153 T172 N176 C177 R178 C183 A184N135-L180 VanDerWaalsContact C-CD2 3.49Å; D136-L180 HydrophobicContact CB-CD2 4.3Å; L139-L180 HydrophobicContact CD2-CD2 4.41Å; L139-L180 WeakPolarHBondContact CD2-O 3.41Å; L153-L180 HydrophobicContact CD2-CB 4.26Å; L153-L180 HydrophobicContact CD2-CD1 4.15Å; T172-L180 HydrophobicContact CG2-CD1 3.92Å; N176-L180 WeakPolarHBondContact O-CG 3.45Å; N176-L180 PolarHBondContact O-N 3.39Å; C177-L180 PolarHBondContact O-N 3.22Å; R178-L180 PolarHBondContact O-N 3.06Å; L180-C183 PolarHBondContact O-N 3.3Å; L180-A184 VanDerWaalsContact O-CB 3.27Å; L180-A184 WeakPolarHBondContact O-CB 3.42Å; L180-A184 PolarHBondContact O-N 3.38Å
181M97.5Very high95.8Very high0 Ų059.2 Ų59.20%030%0.3CS..Hα-helixtrans-66-42.3175.3-70.7175-167.100112.5L153 C177 R178 H179 A184 K185 I191 V218 M221 A222 F225 F227L153-M181 HydrophobicContact CD1-CE 3.64Å; L153-M181 HydrophobicContact CD1-CG 4.1Å; C177-M181 WeakPolarHBondContact O-CG 3.26Å; C177-M181 PolarHBondContact O-N 3.13Å; R178-M181 WeakPolarHBondContact O-CB 3.46Å; R178-M181 PolarHBondContact O-N 3.39Å; H179-M181 VanDerWaalsContact C-N 3.3Å; H179-M181 PolarHBondContact O-N 2.83Å; M181-A184 PolarHBondContact O-N 2.76Å; M181-K185 WeakPolarHBondContact O-CB 3.21Å; M181-K185 PolarHBondContact O-N 3.33Å; M181-I191 HydrophobicContact CB-CD1 4.24Å; M181-I191 HydrophobicContact CG-CD1 3.71Å; M181-V218 HydrophobicContact CE-CB 4.46Å; M181-V218 HydrophobicContact CE-CG1 3.39Å; M181-V218 WeakPolarHBondContact CE-O 3.41Å; M181-M221 HydrophobicContact CE-CB 4.26Å; M181-M221 HydrophobicContact SD-CB 4Å; M181-A222 HydrophobicContact CE-CB 3.81Å; M181-A222 HydrophobicContact SD-CB 3.99Å; M181-F225 HydrophobicContact CB-CD2 3.85Å; M181-F225 HydrophobicContact CB-CE2 4.07Å; M181-F225 HydrophobicContact CB-CG 4.15Å; M181-F225 HydrophobicContact SD-CD2 3.91Å; M181-F225 HydrophobicContact SD-CE2 4.3Å; M181-F227 HydrophobicContact CB-CE2 3.95Å; M181-F227 HydrophobicContact CG-CE2 4.24Å
182E96.4Very high96.2Very high80 Ų8058.5 Ų58.537%0.37429%0.291SS..Hα-helixtrans-56.5-53173.4-70.8166.2178.800110.4R178 H179 A184 K185 E186 F225R178-E182 WeakPolarHBondContact O-CG 3.39Å; R178-E182 PolarHBondContact O-N 3.08Å; R178-E182 VanDerWaalsContact O-N 3.07Å; H179-E182 IonicContact ND1-OE2 3.84Å; H179-E182 WeakPolarHBondContact O-CB 3.34Å; H179-E182 PolarHBondContact O-N 2.88Å; E182-A184 VanDerWaalsContact C-N 3.35Å; E182-A184 PolarHBondContact O-N 3.05Å; E182-K185 WeakPolarHBondContact O-CB 3.35Å; E182-K185 PolarHBondContact O-N 2.85Å; E182-E186 WeakPolarHBondContact O-CG 3.39Å; E182-E186 PolarHBondContact O-N 3.35Å; E182-E186 VanDerWaalsContact O-N 3.08Å; E182-F225 HydrophobicContact CB-CE1 4.4Å; E182-F225 HydrophobicContact CG-CE1 3.47Å; E182-F225 VanDerWaalsContact CG-CE1 3.47Å; E182-F225 HydrophobicContact CG-CZ 3.56Å
183C96.6Very high96.5Very high12 Ų1258.1 Ų58.18%0.08129%0.288CS..Hα-helixtrans-62.1-39.8177.8-69.60000112.7L139 H179 L180 K185 E186 F187L139-C183 HydrophobicContact CD2-CB 3.56Å; H179-C183 VanDerWaalsContact CE1-SG 3.54Å; H179-C183 PolarHBondContact O-N 3.19Å; L180-C183 PolarHBondContact O-N 3.3Å; C183-K185 VanDerWaalsContact C-N 3.28Å; C183-K185 PolarHBondContact O-N 2.86Å; C183-E186 PolarHBondContact O-N 3.17Å; C183-F187 HydrophobicContact CB-CD2 4.38Å; C183-F187 HydrophobicContact CB-CE2 4.02Å; C183-F187 WeakPolarHBondContact O-CD2 3.24Å; C183-F187 VanDerWaalsContact O-CG 3.31Å; C183-F187 WeakPolarHBondContact O-CG 3.38Å; C183-F187 PolarHBondContact O-N 3.35Å
184A96.9Very high96.6Very high0 Ų053.9 Ų53.90%026%0.262CS..Hα-helixtrans-63.7-37.6179.700000111.3L139 L180 M181 E182 F187 G188 I189 I191 F227L139-A184 HydrophobicContact CD1-CB 4.17Å; L139-A184 HydrophobicContact CD2-CB 4.19Å; L180-A184 VanDerWaalsContact O-CB 3.27Å; L180-A184 WeakPolarHBondContact O-CB 3.42Å; L180-A184 PolarHBondContact O-N 3.38Å; M181-A184 PolarHBondContact O-N 2.76Å; E182-A184 VanDerWaalsContact C-N 3.35Å; E182-A184 PolarHBondContact O-N 3.05Å; A184-F187 CarbonylContact O-C 3.59Å; A184-F187 PolarHBondContact O-N 2.95Å; A184-G188 PolarHBondContact O-N 3.38Å; A184-I189 PolarHBondContact O-N 3.33Å; A184-I191 HydrophobicContact CB-CD1 3.53Å; A184-I191 HydrophobicContact CB-CG1 3.89Å; A184-F227 HydrophobicContact CB-CZ 4.03Å
185K96.1Very high96.8Very high122 Ų12251.8 Ų51.853%0.5325%0.251SS..Hα-helixtrans-66-42.7175.1-169.9167.3-176.4164.90111.9M181 E182 C183 F187 G188 F225 F227M181-K185 WeakPolarHBondContact O-CB 3.21Å; M181-K185 PolarHBondContact O-N 3.33Å; E182-K185 WeakPolarHBondContact O-CB 3.35Å; E182-K185 PolarHBondContact O-N 2.85Å; C183-K185 VanDerWaalsContact C-N 3.28Å; C183-K185 PolarHBondContact O-N 2.86Å; K185-F187 VanDerWaalsContact C-N 3.3Å; K185-F187 PolarHBondContact O-N 2.96Å; K185-G188 PolarHBondContact O-N 3.49Å; K185-F225 HydrophobicContact CD-CD1 4.2Å; K185-F225 PolarHBondContact NZ-O 3.06Å; K185-F227 HydrophobicContact CB-CZ 4.15Å
186E95.8Very high96.9Very high152 Ų15243 Ų4371%0.7121%0.213SC*.Hα-helixtrans-61.2-38.7174.2-70.3178.7174.400112.5E182 C183E182-E186 WeakPolarHBondContact O-CG 3.39Å; E182-E186 PolarHBondContact O-N 3.35Å; E182-E186 VanDerWaalsContact O-N 3.08Å; C183-E186 PolarHBondContact O-N 3.17Å
187F95.6Very high96.9Very high86 Ų8644 Ų4438%0.37722%0.215SC..Hα-helixtrans-84.6-6.2179-60.3-37.7000114.4L139 K140 A143 C183 A184 K185 I189L139-F187 HydrophobicContact CD2-CD2 4.32Å; L139-F187 HydrophobicContact CD2-CE2 4.49Å; L139-F187 HydrophobicContact CG-CD2 4.11Å; L139-F187 HydrophobicContact CG-CE2 4.43Å; K140-F187 HydrophobicContact CG-CE2 3.72Å; K140-F187 HydrophobicContact CG-CZ 3.82Å; A143-F187 HydrophobicContact CB-CB 3.81Å; A143-F187 HydrophobicContact CB-CD2 4.2Å; A143-F187 HydrophobicContact CB-CG 4.03Å; C183-F187 HydrophobicContact CB-CD2 4.38Å; C183-F187 HydrophobicContact CB-CE2 4.02Å; C183-F187 WeakPolarHBondContact O-CD2 3.24Å; C183-F187 VanDerWaalsContact O-CG 3.31Å; C183-F187 WeakPolarHBondContact O-CG 3.38Å; C183-F187 PolarHBondContact O-N 3.35Å; A184-F187 CarbonylContact O-C 3.59Å; A184-F187 PolarHBondContact O-N 2.95Å; K185-F187 VanDerWaalsContact C-N 3.3Å; K185-F187 PolarHBondContact O-N 2.96Å; F187-I189 VanDerWaalsContact C-N 3.31Å; F187-I189 HydrophobicContact CB-CG1 4.18Å; F187-I189 PolarHBondContact O-N 3.3Å
188G95.6Very high96.6Very high61 Ų6144 Ų4463%0.62922%0.216SC*.THydrogen-bonded Turntrans68.925.3-177.600000114.4A184 K185A184-G188 PolarHBondContact O-N 3.38Å; K185-G188 PolarHBondContact O-N 3.49Å
189I96.8Very high96.1Very high5 Ų540 Ų403%0.02621%0.206CC..PPolyproline II helixtrans-93139.4179.7-64-67.4000110.5L139 A143 L151 A184 F187 F227L139-I189 HydrophobicContact CD1-CB 4.5Å; L139-I189 HydrophobicContact CD1-CG2 4.34Å; A143-I189 HydrophobicContact CB-CD1 4.24Å; A143-I189 HydrophobicContact CB-CG1 3.84Å; L151-I189 HydrophobicContact CD1-CG2 3.55Å; L151-I189 HydrophobicContact CG-CG2 3.74Å; A184-I189 PolarHBondContact O-N 3.33Å; F187-I189 VanDerWaalsContact C-N 3.31Å; F187-I189 HydrophobicContact CB-CG1 4.18Å; F187-I189 PolarHBondContact O-N 3.3Å; I189-F227 WeakPolarHBondContact O-CE1 3.32Å
190Q97.5Very high95.3Very high111 Ų11137.8 Ų37.852%0.51920%0.199SC..EExtended strand (participates in β ladder)trans-81.8127.2179.3-63.7-17616.500110.8L151 V192L151-Q190 PolarHBondContact N-O 2.69Å; Q190-V192 HydrophobicContact CB-CG1 4.28Å
191I98.3Very high94.4Very high2 Ų242.9 Ų42.91%0.0123%0.226CC..EExtended strand (participates in β ladder)trans-98.9127.1161.6-58.9171.9000106.7L151 L153 M181 A184 F227 M229L151-I191 HydrophobicContact CB-CG1 4.38Å; L153-I191 HydrophobicContact CD1-CD1 4.18Å; L153-I191 HydrophobicContact CD1-CG2 4.22Å; L153-I191 HydrophobicContact CD2-CD1 4.24Å; L153-I191 HydrophobicContact CG-CD1 4.34Å; L153-I191 HydrophobicContact CG-CG2 3.9Å; M181-I191 HydrophobicContact CB-CD1 4.24Å; M181-I191 HydrophobicContact CG-CD1 3.71Å; A184-I191 HydrophobicContact CB-CD1 3.53Å; A184-I191 HydrophobicContact CB-CG1 3.89Å; I191-F227 HydrophobicContact CB-CD1 4.14Å; I191-F227 HydrophobicContact CB-CD2 4.44Å; I191-F227 HydrophobicContact CB-CE1 4.36Å; I191-F227 HydrophobicContact CB-CG 4.19Å; I191-F227 HydrophobicContact CD1-CD2 4.44Å; I191-F227 HydrophobicContact CD1-CE2 3.99Å; I191-F227 HydrophobicContact CD1-CZ 4.05Å; I191-F227 HydrophobicContact CG1-CE1 4.36Å; I191-F227 HydrophobicContact CG1-CZ 4.33Å; I191-M229 HydrophobicContact CG2-CE 4.16Å; I191-M229 HydrophobicContact CG2-SD 3.79Å
192V98.4Very high93.5Very high9 Ų944 Ų446%0.05523%0.233CC..EExtended strand (participates in β ladder)trans-120.6-7.3-174.6-57.90000112.9K150 L151 L152 Q190 M229 N230 M231K150-V192 HydrophobicContact CB-CB 4.47Å; K150-V192 HydrophobicContact CB-CG1 3.78Å; K150-V192 HydrophobicContact CB-CG2 3.82Å; K150-V192 HydrophobicContact CD-CG1 4.19Å; K150-V192 HydrophobicContact CG-CG1 3.94Å; L151-V192 PolarHBondContact O-N 2.6Å; L152-V192 HydrophobicContact CD2-CG2 3.92Å; Q190-V192 HydrophobicContact CB-CG1 4.28Å; V192-M229 CarbonylContact O-C 3.59Å; V192-M229 WeakPolarHBondContact O-CA 3.18Å; V192-N230 PolarHBondContact O-N 3.39Å; V192-N230 PolarHBondContact O-OD1 3.17Å; V192-M231 PolarHBondContact O-N 3.3Å; V192-M231 VanDerWaalsContact O-N 3.13Å
193G98.4Very high92.7Very high0 Ų049.8 Ų49.80%026%0.257CS..EExtended strand (participates in β ladder)trans-177.6-175.4-174.200000115.5L151 L152 L153 M229 M231L151-G193 PolarHBondContact O-N 3.3Å; L152-G193 WeakPolarHBondContact CA-O 3.22Å; L153-G193 PolarHBondContact N-O 2.87Å; G193-M229 VanDerWaalsContact C-CE 3.48Å; G193-M229 VanDerWaalsContact CA-CE 3.45Å; G193-M229 PolarHBondContact N-SD 3.4Å; G193-M231 CarbonylContact C-O 3.6Å; G193-M231 WeakPolarHBondContact CA-O 3.49Å
194V98.6Very high92.2Very high0 Ų053.6 Ų53.60%027%0.274CS..EExtended strand (participates in β ladder)trans-126.8146.3178.81800000108.9L153 I155 A215 V218 F219 M229 M231 L232 D233L153-V194 CarbonylContact O-C 3.34Å; L153-V194 WeakPolarHBondContact O-CA 3.41Å; I155-V194 HydrophobicContact CD1-CG1 3.89Å; I155-V194 HydrophobicContact CG1-CG1 3.91Å; I155-V194 HydrophobicContact CG2-CG1 3.97Å; V194-A215 HydrophobicContact CB-CB 4.24Å; V194-A215 HydrophobicContact CG1-CB 3.83Å; V194-V218 HydrophobicContact CG2-CB 3.8Å; V194-V218 HydrophobicContact CG2-CG1 3.41Å; V194-V218 VanDerWaalsContact CG2-CG1 3.41Å; V194-F219 HydrophobicContact CB-CD2 4.3Å; V194-F219 HydrophobicContact CB-CE2 3.87Å; V194-F219 HydrophobicContact CG2-CD2 3.6Å; V194-F219 HydrophobicContact CG2-CE2 3.61Å; V194-M229 HydrophobicContact CG2-CE 3.81Å; V194-M231 PolarHBondContact N-O 3.48Å; V194-L232 HydrophobicContact CB-CD1 4.24Å; V194-D233 PolarHBondContact O-N 2.93Å
195K98.3Very high91.7Very high11 Ų1155.7 Ų55.75%0.04829%0.285CS..EExtended strand (participates in β ladder)trans-123144.3170.3173175-174.3158.20109.6T132 L152 L153 H154 I155 D233 E271T132-K195 HydrophobicContact CG2-CD 3.43Å; T132-K195 VanDerWaalsContact CG2-CD 3.43Å; L152-K195 HydrophobicContact CB-CB 4.26Å; L153-K195 PolarHBondContact O-N 3.48Å; H154-K195 CarbonylContact C-O 3.54Å; H154-K195 VanDerWaalsContact CA-O 3.29Å; H154-K195 WeakPolarHBondContact CA-O 3.37Å; H154-K195 HydrophobicContact CB-CB 4.37Å; H154-K195 PolarHBondContact CD2-O 2.75Å; I155-K195 WeakPolarHBondContact CG1-O 3.42Å; I155-K195 PolarHBondContact N-O 3.02Å; K195-D233 CarbonylContact C-O 3.58Å; K195-D233 WeakPolarHBondContact CA-O 3.45Å; K195-D233 HydrophobicContact CB-CB 3.97Å; K195-D233 VanDerWaalsContact CD-OD2 3.22Å; K195-D233 WeakPolarHBondContact CD-OD2 3.49Å; K195-D233 WeakPolarHBondContact CE-OD2 3.38Å; K195-D233 HydrophobicContact CG-CB 4.06Å; K195-D233 WeakPolarHBondContact CG-OD2 3.43Å; K195-D233 IonicContact NZ-OD2 2.88Å; K195-E271 IonicContact NZ-OE1 2.68Å; K195-E271 PolarHBondContact NZ-OE1 3.34Å; K195-E271 IonicContact NZ-OE2 2.68Å; K195-E271 PolarHBondContact NZ-OE2 3.23Å
196F96.3Very high91.4Very high0 Ų055 Ų550%028%0.284CS..  trans-138.3170.216060.5-98.6000110.1I155 T157 V198 Y208 A211 I212 A215 L232 D233 I234 G235I155-F196 HydrophobicContact CD1-CB 4.32Å; I155-F196 HydrophobicContact CG1-CB 3.77Å; T157-F196 HydrophobicContact CG2-CB 3.83Å; T157-F196 HydrophobicContact CG2-CD2 4.33Å; T157-F196 HydrophobicContact CG2-CG 4.45Å; F196-V198 HydrophobicContact CD2-CG2 4.21Å; F196-V198 HydrophobicContact CE2-CG2 4.34Å; F196-Y208 HydrophobicContact CE2-CD1 4.05Å; F196-Y208 HydrophobicContact CE2-CE1 4.31Å; F196-A211 HydrophobicContact CB-CB 4.34Å; F196-A211 HydrophobicContact CD1-CB 4.04Å; F196-A211 HydrophobicContact CD2-CB 3.62Å; F196-A211 HydrophobicContact CE1-CB 4.2Å; F196-A211 HydrophobicContact CE2-CB 3.8Å; F196-A211 HydrophobicContact CG-CB 3.75Å; F196-A211 HydrophobicContact CZ-CB 4.08Å; F196-I212 HydrophobicContact CE1-CG1 4.04Å; F196-I212 HydrophobicContact CZ-CG1 3.69Å; F196-A215 HydrophobicContact CD1-CB 4.46Å; F196-L232 HydrophobicContact CE1-CD1 4.16Å; F196-D233 PolarHBondContact N-O 2.9Å; F196-I234 HydrophobicContact CE1-CB 4.37Å; F196-I234 HydrophobicContact CE1-CG2 4.1Å; F196-I234 HydrophobicContact CE2-CB 3.96Å; F196-I234 HydrophobicContact CE2-CG2 4.47Å; F196-I234 WeakPolarHBondContact CE2-O 3.09Å; F196-I234 HydrophobicContact CZ-CB 3.66Å; F196-I234 HydrophobicContact CZ-CG2 3.68Å; F196-I234 CarbonylContact O-C 3.56Å; F196-G235 WeakPolarHBondContact O-CA 3.37Å; F196-G235 PolarHBondContact O-N 2.89Å; F196-G235 VanDerWaalsContact O-N 3.17Å
197H93.6Very high91.2Very high77 Ų7748.1 Ų48.136%0.35625%0.252SS..  trans-141.1122.4174.2-178.788.7000109.7T157 G236T157-H197 PolarHBondContact OG1-O 2.9Å; H197-G236 PolarHBondContact ND1-N 2.8Å
198V90.6Very high91.1Very high1 Ų144.3 Ų44.31%0.00624%0.235CC..  trans-103.9129.2168.5-177.50000107.4T157 F196 C202 T207 Y208 G237T157-V198 HydrophobicContact CG2-CG2 4.26Å; F196-V198 HydrophobicContact CD2-CG2 4.21Å; F196-V198 HydrophobicContact CE2-CG2 4.34Å; V198-C202 HydrophobicContact CG1-CB 3.73Å; V198-T207 HydrophobicContact CG1-CG2 4.08Å; V198-T207 HydrophobicContact CG2-CG2 3.93Å; V198-Y208 HydrophobicContact CB-CD1 4.44Å; V198-Y208 HydrophobicContact CB-CD2 4.32Å; V198-Y208 HydrophobicContact CB-CE1 3.97Å; V198-Y208 HydrophobicContact CB-CE2 3.83Å; V198-Y208 HydrophobicContact CG1-CD2 4.1Å; V198-Y208 HydrophobicContact CG1-CE2 3.69Å; V198-Y208 HydrophobicContact CG2-CD1 3.96Å; V198-Y208 HydrophobicContact CG2-CD2 4.28Å; V198-Y208 HydrophobicContact CG2-CE1 3.93Å; V198-Y208 HydrophobicContact CG2-CE2 4.25Å; V198-Y208 HydrophobicContact CG2-CG 4.14Å; V198-G237 WeakPolarHBondContact O-CA 3.03Å; V198-G237 PolarHBondContact O-N 3.31Å
199S85.9Confident91Very high34 Ų3443.7 Ų43.724%0.23822%0.217CC..  trans-59.9144.5179.8-1790000112D159 N201 C202D159-S199 WeakPolarHBondContact OD2-CB 3.42Å; D159-S199 PolarHBondContact OD2-N 3.29Å; S199-N201 PolarHBondContact O-N 3.42Å; S199-N201 VanDerWaalsContact O-N 3.16Å; S199-N201 PolarHBondContact OG-N 3.02Å; S199-C202 VanDerWaalsContact O-CB 3.22Å; S199-C202 WeakPolarHBondContact O-CB 3.47Å; S199-C202 PolarHBondContact O-N 2.57Å
200S81.3Confident90.9Very high30 Ų3048 Ų4821%0.2124%0.236CC..THydrogen-bonded Turntrans-62.8-18.3170.657.30000113.1
201N78.1Confident90.8Very high107 Ų10742.9 Ų42.957%0.57221%0.213SC*.THydrogen-bonded Turntrans-87.5-7176.3-62.7-26.4000112.5S199 K203S199-N201 PolarHBondContact O-N 3.42Å; S199-N201 VanDerWaalsContact O-N 3.16Å; S199-N201 PolarHBondContact OG-N 3.02Å; N201-K203 PolarHBondContact O-N 2.78Å
202C79.2Confident90.8Very high24 Ų2442.8 Ų42.816%0.16221%0.213CC..  trans-71.3120.3175.5-1720000109.9V198 S199V198-C202 HydrophobicContact CG1-CB 3.73Å; S199-C202 VanDerWaalsContact O-CB 3.22Å; S199-C202 WeakPolarHBondContact O-CB 3.47Å; S199-C202 PolarHBondContact O-N 2.57Å
203K79.2Confident90.7Very high201 Ų20144.6 Ų44.687%0.87423%0.226SC*.  trans-88.9-15.9177.3-61.6-173.7-175.3-177.90112.7N201 L205N201-K203 PolarHBondContact O-N 2.78Å; K203-L205 PolarHBondContact O-N 3.19Å
204E85.9Confident90.6Very high93 Ų9347.1 Ų47.144%0.43524%0.239SC..  trans-90.498.7-176.4-65.4-170.2-178.200110.6Q206 T207E204-Q206 PolarHBondContact O-N 2.83Å; E204-T207 PolarHBondContact O-N 3.44Å; E204-T207 VanDerWaalsContact O-N 3.12Å; E204-T207 PolarHBondContact O-OG1 2.57Å
205L87.2Confident90.6Very high43 Ų4347.1 Ų47.123%0.22524%0.239CC..THydrogen-bonded Turntrans-62.6-15.8177.1-61.3175.7000113.2K203 T207 Y208 E247 V248 V251K203-L205 PolarHBondContact O-N 3.19Å; L205-T207 PolarHBondContact O-N 3.36Å; L205-Y208 PolarHBondContact O-N 3.27Å; L205-E247 HydrophobicContact CD1-CB 4.32Å; L205-V248 HydrophobicContact CD2-CG2 4.05Å; L205-V251 HydrophobicContact CB-CG1 4.43Å; L205-V251 HydrophobicContact CB-CG2 3.98Å; L205-V251 HydrophobicContact CD1-CG2 3.78Å; L205-V251 HydrophobicContact CG-CG2 4.43Å
206Q89.8Confident90.6Very high109 Ų10948.9 Ų48.951%0.50925%0.246SC..Hα-helixtrans-61.1-28.6174.5-64.4-58.9-50.400112.5E204 Y208 I209 H210E204-Q206 PolarHBondContact O-N 2.83Å; Q206-Y208 VanDerWaalsContact C-N 3.27Å; Q206-Y208 PolarHBondContact O-N 3.26Å; Q206-I209 WeakPolarHBondContact O-CA 3.48Å; Q206-I209 WeakPolarHBondContact O-CB 3.4Å; Q206-I209 PolarHBondContact O-N 2.88Å; Q206-H210 PolarHBondContact O-N 3.24Å; Q206-H210 VanDerWaalsContact O-N 3.08Å
207T91.6Very high90.7Very high6 Ų651.3 Ų51.34%0.03726%0.262CS..Hα-helixtrans-60.2-37.8177.1-52.70000111.9E158 D159 V198 E204 L205 I209 H210 A211E158-T207 WeakPolarHBondContact O-CG2 3.24Å; E158-T207 PolarHBondContact O-OG1 2.68Å; D159-T207 WeakPolarHBondContact OD1-CG2 3.17Å; V198-T207 HydrophobicContact CG1-CG2 4.08Å; V198-T207 HydrophobicContact CG2-CG2 3.93Å; E204-T207 PolarHBondContact O-N 3.44Å; E204-T207 VanDerWaalsContact O-N 3.12Å; E204-T207 PolarHBondContact O-OG1 2.57Å; L205-T207 PolarHBondContact O-N 3.36Å; T207-I209 VanDerWaalsContact C-N 3.3Å; T207-I209 PolarHBondContact O-N 3.11Å; T207-H210 PolarHBondContact O-N 3.13Å; T207-A211 VanDerWaalsContact O-CB 3.31Å; T207-A211 WeakPolarHBondContact O-CB 3.28Å; T207-A211 PolarHBondContact O-N 2.96Å
208Y92.8Very high90.9Very high7 Ų747.6 Ų47.63%0.02725%0.245CC..Hα-helixtrans-64.4-35.6173.3-80.3-80.4000112.2F196 V198 L205 Q206 A211 I212 V248 I252F196-Y208 HydrophobicContact CE2-CD1 4.05Å; F196-Y208 HydrophobicContact CE2-CE1 4.31Å; V198-Y208 HydrophobicContact CB-CD1 4.44Å; V198-Y208 HydrophobicContact CB-CD2 4.32Å; V198-Y208 HydrophobicContact CB-CE1 3.97Å; V198-Y208 HydrophobicContact CB-CE2 3.83Å; V198-Y208 HydrophobicContact CG1-CD2 4.1Å; V198-Y208 HydrophobicContact CG1-CE2 3.69Å; V198-Y208 HydrophobicContact CG2-CD1 3.96Å; V198-Y208 HydrophobicContact CG2-CD2 4.28Å; V198-Y208 HydrophobicContact CG2-CE1 3.93Å; V198-Y208 HydrophobicContact CG2-CE2 4.25Å; V198-Y208 HydrophobicContact CG2-CG 4.14Å; L205-Y208 PolarHBondContact O-N 3.27Å; Q206-Y208 VanDerWaalsContact C-N 3.27Å; Q206-Y208 PolarHBondContact O-N 3.26Å; Y208-A211 PolarHBondContact O-N 2.99Å; Y208-I212 WeakPolarHBondContact O-CB 3.27Å; Y208-I212 VanDerWaalsContact O-CG1 3.23Å; Y208-I212 WeakPolarHBondContact O-CG1 3.27Å; Y208-I212 PolarHBondContact O-N 3.34Å; Y208-V248 HydrophobicContact CE1-CG1 4.26Å; Y208-V248 HydrophobicContact CE2-CG1 4.14Å; Y208-V248 HydrophobicContact CE2-CG2 4.16Å; Y208-I252 HydrophobicContact CD1-CG2 3.81Å; Y208-I252 HydrophobicContact CG-CG2 3.99Å
209I93.9Very high91.3Very high47 Ų4747.9 Ų47.924%0.24125%0.246CC..Hα-helixtrans-64.7-49.2179.3-51.2-165.6000110.3Q206 T207 S213 V251 L255Q206-I209 WeakPolarHBondContact O-CA 3.48Å; Q206-I209 WeakPolarHBondContact O-CB 3.4Å; Q206-I209 PolarHBondContact O-N 2.88Å; T207-I209 VanDerWaalsContact C-N 3.3Å; T207-I209 PolarHBondContact O-N 3.11Å; I209-S213 WeakPolarHBondContact O-CB 3.42Å; I209-S213 PolarHBondContact O-N 3.43Å; I209-V251 HydrophobicContact CD1-CG1 3.91Å; I209-V251 HydrophobicContact CG1-CG1 3.61Å; I209-L255 HydrophobicContact CB-CD1 3.98Å; I209-L255 HydrophobicContact CG1-CD1 3.82Å; I209-L255 HydrophobicContact CG2-CD1 3.9Å; I209-L255 HydrophobicContact CG2-CD2 4.3Å
210H94.3Very high91.9Very high95 Ų9549.6 Ų49.644%0.4425%0.253SS..Hα-helixtrans-61.8-46.5177.2-63170.4000111.1Q206 T207 I212 S213 D214Q206-H210 PolarHBondContact O-N 3.24Å; Q206-H210 VanDerWaalsContact O-N 3.08Å; T207-H210 PolarHBondContact O-N 3.13Å; H210-I212 PolarHBondContact O-N 3.27Å; H210-S213 PolarHBondContact O-N 3.3Å; H210-D214 WeakPolarHBondContact O-CB 3.49Å; H210-D214 PolarHBondContact O-N 3.31Å
211A95.6Very high92.7Very high4 Ų449.4 Ų49.43%0.03325%0.249CC..Hα-helixtrans-61.4-41.2-179.100000113.4T157 F196 T207 Y208 A215T157-A211 HydrophobicContact CG2-CB 3.92Å; F196-A211 HydrophobicContact CB-CB 4.34Å; F196-A211 HydrophobicContact CD1-CB 4.04Å; F196-A211 HydrophobicContact CD2-CB 3.62Å; F196-A211 HydrophobicContact CE1-CB 4.2Å; F196-A211 HydrophobicContact CE2-CB 3.8Å; F196-A211 HydrophobicContact CG-CB 3.75Å; F196-A211 HydrophobicContact CZ-CB 4.08Å; T207-A211 VanDerWaalsContact O-CB 3.31Å; T207-A211 WeakPolarHBondContact O-CB 3.28Å; T207-A211 PolarHBondContact O-N 2.96Å; Y208-A211 PolarHBondContact O-N 2.99Å; A211-A215 WeakPolarHBondContact O-CB 3.33Å; A211-A215 PolarHBondContact O-N 2.75Å
212I97.1Very high93.6Very high0 Ų044.3 Ų44.30%022%0.222CC..Hα-helixtrans-69.7-39.5177.4-65.3169.8000110.8F196 Y208 H210 A215 R216 I252 L255 L256 Y259 F260F196-I212 HydrophobicContact CE1-CG1 4.04Å; F196-I212 HydrophobicContact CZ-CG1 3.69Å; Y208-I212 WeakPolarHBondContact O-CB 3.27Å; Y208-I212 VanDerWaalsContact O-CG1 3.23Å; Y208-I212 WeakPolarHBondContact O-CG1 3.27Å; Y208-I212 PolarHBondContact O-N 3.34Å; H210-I212 PolarHBondContact O-N 3.27Å; I212-A215 PolarHBondContact O-N 2.93Å; I212-R216 PolarHBondContact O-N 3.35Å; I212-I252 HydrophobicContact CD1-CB 3.8Å; I212-I252 HydrophobicContact CD1-CG2 3.8Å; I212-L255 HydrophobicContact CD1-CB 4.23Å; I212-L255 HydrophobicContact CD1-CD1 4.13Å; I212-L255 HydrophobicContact CG2-CB 4.06Å; I212-L256 HydrophobicContact CD1-CD2 4.43Å; I212-L256 HydrophobicContact CG2-CD2 4.42Å; I212-Y259 HydrophobicContact CG2-CD2 3.83Å; I212-F260 HydrophobicContact CG2-CD2 4.29Å; I212-F260 HydrophobicContact CG2-CE2 3.9Å
213S96.7Very high94.4Very high47 Ų4750 Ų5033%0.32925%0.246SC..Hα-helixtrans-63.1-43.91751780000111.7I209 H210 R216 C217I209-S213 WeakPolarHBondContact O-CB 3.42Å; I209-S213 PolarHBondContact O-N 3.43Å; H210-S213 PolarHBondContact O-N 3.3Å; S213-R216 WeakPolarHBondContact O-CB 3.32Å; S213-R216 PolarHBondContact O-N 3.4Å; S213-C217 PolarHBondContact O-N 2.76Å
214D97.6Very high95.2Very high53 Ų5346.7 Ų46.728%0.28323%0.234SC..Hα-helixtrans-64.1-41.6176.4-78.62.1000111.2I155 L174 H210 R216 C217 V218I155-D214 HydrophobicContact CD1-CB 3.81Å; L174-D214 HydrophobicContact CD1-CB 4.46Å; L174-D214 HydrophobicContact CD2-CB 3.96Å; H210-D214 WeakPolarHBondContact O-CB 3.49Å; H210-D214 PolarHBondContact O-N 3.31Å; D214-R216 VanDerWaalsContact C-N 3.3Å; D214-R216 PolarHBondContact O-N 2.94Å; D214-C217 WeakPolarHBondContact O-CB 3.49Å; D214-C217 PolarHBondContact O-N 3.15Å; D214-V218 VanDerWaalsContact O-CG2 3.29Å; D214-V218 WeakPolarHBondContact O-CG2 3.31Å; D214-V218 PolarHBondContact O-N 3.26Å
215A98.3Very high95.7Very high0 Ų043.9 Ų43.90%022%0.22CC..Hα-helixtrans-59-42.2172.900000111.5I155 V194 F196 A211 I212 C217 V218 F219 L232 F260I155-A215 HydrophobicContact CD1-CB 4.18Å; V194-A215 HydrophobicContact CB-CB 4.24Å; V194-A215 HydrophobicContact CG1-CB 3.83Å; F196-A215 HydrophobicContact CD1-CB 4.46Å; A211-A215 WeakPolarHBondContact O-CB 3.33Å; A211-A215 PolarHBondContact O-N 2.75Å; I212-A215 PolarHBondContact O-N 2.93Å; A215-C217 PolarHBondContact O-N 3.46Å; A215-V218 PolarHBondContact O-N 2.83Å; A215-F219 VanDerWaalsContact O-CD2 3.25Å; A215-F219 WeakPolarHBondContact O-CD2 3.21Å; A215-F219 PolarHBondContact O-N 3.07Å; A215-L232 HydrophobicContact CB-CD1 3.71Å; A215-F260 HydrophobicContact CB-CZ 4.24Å
216R98.3Very high96.2Very high48 Ų4844.8 Ų44.818%0.18124%0.24CC..Hα-helixtrans-59.7-45.5175.3-178.464.6-97.2175.9-7.2111.7I212 S213 D214 V218 F219 D220 Y259 F260I212-R216 PolarHBondContact O-N 3.35Å; S213-R216 WeakPolarHBondContact O-CB 3.32Å; S213-R216 PolarHBondContact O-N 3.4Å; D214-R216 VanDerWaalsContact C-N 3.3Å; D214-R216 PolarHBondContact O-N 2.94Å; R216-V218 VanDerWaalsContact C-N 3.27Å; R216-V218 PolarHBondContact O-N 2.55Å; R216-F219 VanDerWaalsContact NH2-CB 3.3Å; R216-F219 WeakPolarHBondContact O-CB 3.4Å; R216-F219 PolarHBondContact O-N 3.32Å; R216-F219 VanDerWaalsContact O-N 3.14Å; R216-D220 IonicContact CZ-OD1 3.98Å; R216-D220 IonicContact NE-OD1 3.3Å; R216-D220 PolarHBondContact NE-OD1 3.2Å; R216-D220 IonicContact NE-OD2 3.43Å; R216-D220 IonicContact NH2-OD1 3.02Å; R216-D220 PolarHBondContact NH2-OD1 3.22Å; R216-D220 VanDerWaalsContact O-CG 3.27Å; R216-D220 PolarHBondContact O-N 2.94Å; R216-Y259 HydrophobicContact CB-CD1 4.2Å; R216-Y259 HydrophobicContact CB-CG 4.15Å; R216-Y259 WeakPolarHBondContact CD-O 3.42Å; R216-Y259 HydrophobicContact CG-CD1 3.74Å; R216-Y259 HydrophobicContact CG-CE1 4.4Å; R216-Y259 HydrophobicContact CG-CG 4.1Å; R216-Y259 PolarHBondContact NH1-O 3.5Å; R216-F260 HydrophobicContact CB-CE2 4.38Å; R216-F260 HydrophobicContact CB-CZ 4.07Å
217C98.1Very high96.5Very high51 Ų5141.1 Ų41.135%0.34522%0.222SC..Hα-helixtrans-57.6-41175.8-178.10000111.9S213 D214 A215 D220 M221S213-C217 PolarHBondContact O-N 2.76Å; D214-C217 WeakPolarHBondContact O-CB 3.49Å; D214-C217 PolarHBondContact O-N 3.15Å; A215-C217 PolarHBondContact O-N 3.46Å; C217-D220 PolarHBondContact O-N 2.84Å; C217-M221 WeakPolarHBondContact O-CG 3.35Å; C217-M221 PolarHBondContact O-N 3.17Å
218V98.4Very high96.8Very high0 Ų049.7 Ų49.70%026%0.259CS..Hα-helixtrans-68-38.2177.2177.80000111.8L153 I155 L174 C177 M181 V194 D214 A215 R216 M221 A222L153-V218 HydrophobicContact CD1-CG1 4.2Å; I155-V218 HydrophobicContact CG2-CG2 4.04Å; L174-V218 HydrophobicContact CD2-CG2 3.47Å; L174-V218 VanDerWaalsContact CD2-CG2 3.47Å; C177-V218 HydrophobicContact CB-CG1 4.46Å; C177-V218 HydrophobicContact CB-CG2 4.27Å; M181-V218 HydrophobicContact CE-CB 4.46Å; M181-V218 HydrophobicContact CE-CG1 3.39Å; M181-V218 WeakPolarHBondContact CE-O 3.41Å; V194-V218 HydrophobicContact CG2-CB 3.8Å; V194-V218 HydrophobicContact CG2-CG1 3.41Å; V194-V218 VanDerWaalsContact CG2-CG1 3.41Å; D214-V218 VanDerWaalsContact O-CG2 3.29Å; D214-V218 WeakPolarHBondContact O-CG2 3.31Å; D214-V218 PolarHBondContact O-N 3.26Å; A215-V218 PolarHBondContact O-N 2.83Å; R216-V218 VanDerWaalsContact C-N 3.27Å; R216-V218 PolarHBondContact O-N 2.55Å; V218-M221 HydrophobicContact CB-CE 4.3Å; V218-M221 HydrophobicContact CG2-CE 3.87Å; V218-M221 PolarHBondContact O-N 3.25Å; V218-A222 WeakPolarHBondContact O-CB 3.19Å; V218-A222 PolarHBondContact O-N 2.94Å
219F98.5Very high97Very high6 Ų650.5 Ų50.53%0.02626%0.263CS..Hα-helixtrans-62.1-42.9172.7-89.3-117.4000111.9V194 A215 R216 A222 E223 M229 M231 L232 F260 V266V194-F219 HydrophobicContact CB-CD2 4.3Å; V194-F219 HydrophobicContact CB-CE2 3.87Å; V194-F219 HydrophobicContact CG2-CD2 3.6Å; V194-F219 HydrophobicContact CG2-CE2 3.61Å; A215-F219 VanDerWaalsContact O-CD2 3.25Å; A215-F219 WeakPolarHBondContact O-CD2 3.21Å; A215-F219 PolarHBondContact O-N 3.07Å; R216-F219 VanDerWaalsContact NH2-CB 3.3Å; R216-F219 WeakPolarHBondContact O-CB 3.4Å; R216-F219 PolarHBondContact O-N 3.32Å; R216-F219 VanDerWaalsContact O-N 3.14Å; F219-A222 PolarHBondContact O-N 3.24Å; F219-E223 PolarHBondContact O-N 3.1Å; F219-E223 VanDerWaalsContact O-N 3.07Å; F219-M229 HydrophobicContact CD1-CB 3.34Å; F219-M229 HydrophobicContact CD1-CG 4.09Å; F219-M229 HydrophobicContact CD2-CE 3.94Å; F219-M229 HydrophobicContact CE1-CB 3.43Å; F219-M229 VanDerWaalsContact CE1-CB 3.43Å; F219-M229 HydrophobicContact CE1-CG 4.48Å; F219-M229 HydrophobicContact CE2-CE 4.12Å; F219-M229 HydrophobicContact CG-CB 4.06Å; F219-M229 HydrophobicContact CG-CE 4.19Å; F219-M229 HydrophobicContact CG-CG 4.35Å; F219-M229 HydrophobicContact CZ-CB 4.22Å; F219-M229 HydrophobicContact CZ-CE 4.5Å; F219-M231 VanDerWaalsContact CZ-O 3.3Å; F219-M231 WeakPolarHBondContact CZ-O 3.5Å; F219-L232 HydrophobicContact CE2-CD1 4.34Å; F219-L232 HydrophobicContact CZ-CB 4.28Å; F219-F260 HydrophobicContact CB-CE1 4.42Å; F219-F260 HydrophobicContact CD1-CD1 4.45Å; F219-F260 AromaticContact CD1-CE1 3.84Å; F219-F260 HydrophobicContact CD1-CE1 3.84Å; F219-F260 AromaticContact CD2-CE1 3.76Å; F219-F260 HydrophobicContact CD2-CE1 3.76Å; F219-F260 HydrophobicContact CD2-CZ 4.16Å; F219-F260 HydrophobicContact CE1-CD1 4.28Å; F219-F260 AromaticContact CE1-CE1 3.9Å; F219-F260 HydrophobicContact CE1-CE1 3.9Å; F219-F260 AromaticContact CE2-CE1 3.79Å; F219-F260 HydrophobicContact CE2-CE1 3.79Å; F219-F260 HydrophobicContact CE2-CZ 4.25Å; F219-F260 AromaticContact CG-CE1 3.76Å; F219-F260 HydrophobicContact CG-CE1 3.76Å; F219-F260 HydrophobicContact CG-CZ 4.48Å; F219-F260 HydrophobicContact CZ-CD1 4.41Å; F219-F260 AromaticContact CZ-CE1 3.86Å; F219-F260 HydrophobicContact CZ-CE1 3.86Å; F219-V266 HydrophobicContact CD1-CG2 4.39Å; F219-V266 HydrophobicContact CE1-CG1 3.97Å; F219-V266 HydrophobicContact CE1-CG2 3.67Å; F219-V266 HydrophobicContact CZ-CG1 3.98Å; F219-V266 HydrophobicContact CZ-CG2 4.5Å
220D98Very high97.2Very high71 Ų7151.6 Ų51.638%0.3827%0.27SS..Hα-helixtrans-62.6-46.4177.9-60.9-20.4000110.9R216 C217 A222 E223 E224R216-D220 IonicContact CZ-OD1 3.98Å; R216-D220 IonicContact NE-OD1 3.3Å; R216-D220 PolarHBondContact NE-OD1 3.2Å; R216-D220 IonicContact NE-OD2 3.43Å; R216-D220 IonicContact NH2-OD1 3.02Å; R216-D220 PolarHBondContact NH2-OD1 3.22Å; R216-D220 VanDerWaalsContact O-CG 3.27Å; R216-D220 PolarHBondContact O-N 2.94Å; C217-D220 PolarHBondContact O-N 2.84Å; D220-A222 VanDerWaalsContact C-N 3.31Å; D220-A222 PolarHBondContact O-N 3.32Å; D220-E223 PolarHBondContact O-N 3.44Å; D220-E224 PolarHBondContact O-N 3.49Å
221M97.9Very high97.4Very high26 Ų2648 Ų4813%0.12825%0.253CS..Hα-helixtrans-57.7-44.7174.1-72.6-171.3-71.800111.5C177 R178 M181 C217 V218 E223 E224 F225C177-M221 HydrophobicContact CB-CE 4.37Å; R178-M221 HydrophobicContact CB-SD 4.21Å; M181-M221 HydrophobicContact CE-CB 4.26Å; M181-M221 HydrophobicContact SD-CB 4Å; C217-M221 WeakPolarHBondContact O-CG 3.35Å; C217-M221 PolarHBondContact O-N 3.17Å; V218-M221 HydrophobicContact CB-CE 4.3Å; V218-M221 HydrophobicContact CG2-CE 3.87Å; V218-M221 PolarHBondContact O-N 3.25Å; M221-E223 VanDerWaalsContact C-N 3.28Å; M221-E223 PolarHBondContact O-N 3Å; M221-E224 WeakPolarHBondContact O-CB 3.44Å; M221-E224 PolarHBondContact O-N 3.08Å; M221-E224 VanDerWaalsContact O-N 3.15Å; M221-F225 VanDerWaalsContact O-CD2 3.23Å; M221-F225 WeakPolarHBondContact O-CD2 3.42Å; M221-F225 PolarHBondContact O-N 3.15Å
222A97.5Very high97.6Very high0 Ų047.9 Ų47.90%025%0.252CS..Hα-helixtrans-63.2-34.8-178.400000112.6M181 V218 F219 D220 F225 G226 F227 M229M181-A222 HydrophobicContact CE-CB 3.81Å; M181-A222 HydrophobicContact SD-CB 3.99Å; V218-A222 WeakPolarHBondContact O-CB 3.19Å; V218-A222 PolarHBondContact O-N 2.94Å; F219-A222 PolarHBondContact O-N 3.24Å; D220-A222 VanDerWaalsContact C-N 3.31Å; D220-A222 PolarHBondContact O-N 3.32Å; A222-F225 PolarHBondContact O-N 2.96Å; A222-G226 PolarHBondContact O-N 3.48Å; A222-F227 HydrophobicContact CB-CB 4.15Å; A222-F227 HydrophobicContact CB-CD2 4.37Å; A222-F227 WeakPolarHBondContact O-CB 3.45Å; A222-F227 PolarHBondContact O-N 2.95Å; A222-M229 HydrophobicContact CB-CE 3.97Å; A222-M229 HydrophobicContact CB-CG 3.5Å; A222-M229 VanDerWaalsContact CB-CG 3.5Å; A222-M229 HydrophobicContact CB-SD 3.6Å
223E95.6Very high97.6Very high143 Ų14347.9 Ų47.967%0.66825%0.252SS*.Hα-helixtrans-63.8-40.2174-172172.1-171.100111.7F219 D220 M221 F225 G226F219-E223 PolarHBondContact O-N 3.1Å; F219-E223 VanDerWaalsContact O-N 3.07Å; D220-E223 PolarHBondContact O-N 3.44Å; M221-E223 VanDerWaalsContact C-N 3.28Å; M221-E223 PolarHBondContact O-N 3Å; E223-F225 PolarHBondContact O-N 3.35Å; E223-G226 WeakPolarHBondContact O-CA 3.41Å; E223-G226 PolarHBondContact O-N 3.12Å
224E96.7Very high97.7Very high132 Ų13245.6 Ų45.662%0.61724%0.236SC*.Hα-helixtrans-58.2-34.7173.3-60.8178.4177.300112.2R178 D220 M221 G226R178-E224 IonicContact NH2-OE2 3.85Å; R178-E224 PolarHBondContact NH2-OE2 2.96Å; D220-E224 PolarHBondContact O-N 3.49Å; M221-E224 WeakPolarHBondContact O-CB 3.44Å; M221-E224 PolarHBondContact O-N 3.08Å; M221-E224 VanDerWaalsContact O-N 3.15Å; E224-G226 VanDerWaalsContact C-N 3.29Å
225F96.2Very high97.5Very high34 Ų3443.1 Ų43.115%0.14922%0.223CC..Hα-helixtrans-79.1-11.5175.6-75.9-82.3000113.5R178 M181 E182 K185 M221 A222 E223 F227R178-F225 HydrophobicContact CG-CE2 3.93Å; R178-F225 HydrophobicContact CG-CZ 4.01Å; M181-F225 HydrophobicContact CB-CD2 3.85Å; M181-F225 HydrophobicContact CB-CE2 4.07Å; M181-F225 HydrophobicContact CB-CG 4.15Å; M181-F225 HydrophobicContact SD-CD2 3.91Å; M181-F225 HydrophobicContact SD-CE2 4.3Å; E182-F225 HydrophobicContact CB-CE1 4.4Å; E182-F225 HydrophobicContact CG-CE1 3.47Å; E182-F225 VanDerWaalsContact CG-CE1 3.47Å; E182-F225 HydrophobicContact CG-CZ 3.56Å; K185-F225 HydrophobicContact CD-CD1 4.2Å; K185-F225 PolarHBondContact NZ-O 3.06Å; M221-F225 VanDerWaalsContact O-CD2 3.23Å; M221-F225 WeakPolarHBondContact O-CD2 3.42Å; M221-F225 PolarHBondContact O-N 3.15Å; A222-F225 PolarHBondContact O-N 2.96Å; E223-F225 PolarHBondContact O-N 3.35Å; F225-F227 HydrophobicContact CB-CD2 3.62Å; F225-F227 HydrophobicContact CB-CE2 3.65Å; F225-F227 HydrophobicContact CG-CE2 4.35Å
226G96.7Very high97.2Very high62 Ų6243.6 Ų43.664%0.63923%0.227SC*.THydrogen-bonded Turntrans85.717.9-177.900000114.3A222 E223 E224A222-G226 PolarHBondContact O-N 3.48Å; E223-G226 WeakPolarHBondContact O-CA 3.41Å; E223-G226 PolarHBondContact O-N 3.12Å; E224-G226 VanDerWaalsContact C-N 3.29Å
227F97.9Very high96.6Very high31 Ų3141.3 Ų41.314%0.13622%0.219CC..  trans-76.3145.3172.7-67.1-66.3000110.9M181 A184 K185 I189 I191 A222 F225 M229M181-F227 HydrophobicContact CB-CE2 3.95Å; M181-F227 HydrophobicContact CG-CE2 4.24Å; A184-F227 HydrophobicContact CB-CZ 4.03Å; K185-F227 HydrophobicContact CB-CZ 4.15Å; I189-F227 WeakPolarHBondContact O-CE1 3.32Å; I191-F227 HydrophobicContact CB-CD1 4.14Å; I191-F227 HydrophobicContact CB-CD2 4.44Å; I191-F227 HydrophobicContact CB-CE1 4.36Å; I191-F227 HydrophobicContact CB-CG 4.19Å; I191-F227 HydrophobicContact CD1-CD2 4.44Å; I191-F227 HydrophobicContact CD1-CE2 3.99Å; I191-F227 HydrophobicContact CD1-CZ 4.05Å; I191-F227 HydrophobicContact CG1-CE1 4.36Å; I191-F227 HydrophobicContact CG1-CZ 4.33Å; A222-F227 HydrophobicContact CB-CB 4.15Å; A222-F227 HydrophobicContact CB-CD2 4.37Å; A222-F227 WeakPolarHBondContact O-CB 3.45Å; A222-F227 PolarHBondContact O-N 2.95Å; F225-F227 HydrophobicContact CB-CD2 3.62Å; F225-F227 HydrophobicContact CB-CE2 3.65Å; F225-F227 HydrophobicContact CG-CE2 4.35Å; F227-M229 HydrophobicContact CB-SD 4.45Å
228K96.7Very high96.4Very high186 Ų18638.9 Ų38.981%0.80920%0.203SC*.  trans-98.791.9175.4-67.3-174.6178.6-175.60109.1
229M97.9Very high96Very high25 Ų2541.5 Ų41.512%0.12322%0.219CC..  trans-80130.3179.2-56.2-68.7-84.400110.4I191 V192 G193 V194 F219 A222 F227I191-M229 HydrophobicContact CG2-CE 4.16Å; I191-M229 HydrophobicContact CG2-SD 3.79Å; V192-M229 CarbonylContact O-C 3.59Å; V192-M229 WeakPolarHBondContact O-CA 3.18Å; G193-M229 VanDerWaalsContact C-CE 3.48Å; G193-M229 VanDerWaalsContact CA-CE 3.45Å; G193-M229 PolarHBondContact N-SD 3.4Å; V194-M229 HydrophobicContact CG2-CE 3.81Å; F219-M229 HydrophobicContact CD1-CB 3.34Å; F219-M229 HydrophobicContact CD1-CG 4.09Å; F219-M229 HydrophobicContact CD2-CE 3.94Å; F219-M229 HydrophobicContact CE1-CB 3.43Å; F219-M229 VanDerWaalsContact CE1-CB 3.43Å; F219-M229 HydrophobicContact CE1-CG 4.48Å; F219-M229 HydrophobicContact CE2-CE 4.12Å; F219-M229 HydrophobicContact CG-CB 4.06Å; F219-M229 HydrophobicContact CG-CE 4.19Å; F219-M229 HydrophobicContact CG-CG 4.35Å; F219-M229 HydrophobicContact CZ-CB 4.22Å; F219-M229 HydrophobicContact CZ-CE 4.5Å; A222-M229 HydrophobicContact CB-CE 3.97Å; A222-M229 HydrophobicContact CB-CG 3.5Å; A222-M229 VanDerWaalsContact CB-CG 3.5Å; A222-M229 HydrophobicContact CB-SD 3.6Å; F227-M229 HydrophobicContact CB-SD 4.45Å
230N97.8Very high95.5Very high70 Ų7041.7 Ų41.737%0.37422%0.223SC..  trans-147.410.1-17768.92.2000114.2V192 N267V192-N230 PolarHBondContact O-N 3.39Å; V192-N230 PolarHBondContact O-OD1 3.17Å; N230-N267 PolarHBondContact O-N 3.08Å
231M98.4Very high95.2Very high20 Ų2040.8 Ų40.810%0.09922%0.222CC..EExtended strand (participates in β ladder)trans-141.1130-178.1-173.8167.7-78.100111.7I130 L152 V192 G193 V194 F219 N267 I269I130-M231 HydrophobicContact CD1-CE 4.02Å; I130-M231 HydrophobicContact CD1-SD 4.31Å; I130-M231 HydrophobicContact CG2-SD 4.13Å; L152-M231 HydrophobicContact CD1-CG 4.44Å; L152-M231 HydrophobicContact CD1-SD 4.03Å; L152-M231 HydrophobicContact CD2-CB 3.91Å; L152-M231 HydrophobicContact CD2-CG 3.85Å; L152-M231 HydrophobicContact CD2-SD 3.92Å; L152-M231 HydrophobicContact CG-SD 4.49Å; V192-M231 PolarHBondContact O-N 3.3Å; V192-M231 VanDerWaalsContact O-N 3.13Å; G193-M231 CarbonylContact C-O 3.6Å; G193-M231 WeakPolarHBondContact CA-O 3.49Å; V194-M231 PolarHBondContact N-O 3.48Å; F219-M231 VanDerWaalsContact CZ-O 3.3Å; F219-M231 WeakPolarHBondContact CZ-O 3.5Å; M231-N267 WeakPolarHBondContact CA-O 3.15Å; M231-I269 HydrophobicContact CG-CD1 4.25Å; M231-I269 HydrophobicContact CG-CG1 4.5Å; M231-I269 HydrophobicContact SD-CD1 3.97Å
232L98.6Very high94.9Very high0 Ų044.6 Ų44.60%024%0.239CC..EExtended strand (participates in β ladder)trans-123121.5172.217665000108.8V194 F196 A215 F219 I234 L256 F260 V266 N267 V268 I269V194-L232 HydrophobicContact CB-CD1 4.24Å; F196-L232 HydrophobicContact CE1-CD1 4.16Å; A215-L232 HydrophobicContact CB-CD1 3.71Å; F219-L232 HydrophobicContact CE2-CD1 4.34Å; F219-L232 HydrophobicContact CZ-CB 4.28Å; L232-I234 HydrophobicContact CD2-CG2 4.31Å; L232-I234 HydrophobicContact CG-CG2 4.22Å; L232-L256 HydrophobicContact CD2-CD2 3.74Å; L232-F260 HydrophobicContact CD2-CD1 4.49Å; L232-F260 HydrophobicContact CD2-CD2 3.62Å; L232-F260 HydrophobicContact CD2-CE1 4.46Å; L232-F260 HydrophobicContact CD2-CE2 3.58Å; L232-F260 HydrophobicContact CD2-CG 4.09Å; L232-F260 HydrophobicContact CD2-CZ 4.01Å; L232-V266 HydrophobicContact CB-CG1 4.05Å; L232-N267 PolarHBondContact N-O 3.14Å; L232-V268 HydrophobicContact CD2-CG1 4.46Å; L232-V268 CarbonylContact O-C 3.55Å; L232-V268 WeakPolarHBondContact O-CA 3.07Å; L232-I269 PolarHBondContact O-N 3.08Å
233D98.6Very high94.7Very high0 Ų050.3 Ų50.30%027%0.269CS..EExtended strand (participates in β ladder)trans-104.6115.9174.4178.36.2000110.2L152 V194 K195 F196 G235 I269L152-D233 HydrophobicContact CD1-CB 4.23Å; V194-D233 PolarHBondContact O-N 2.93Å; K195-D233 CarbonylContact C-O 3.58Å; K195-D233 WeakPolarHBondContact CA-O 3.45Å; K195-D233 HydrophobicContact CB-CB 3.97Å; K195-D233 VanDerWaalsContact CD-OD2 3.22Å; K195-D233 WeakPolarHBondContact CD-OD2 3.49Å; K195-D233 WeakPolarHBondContact CE-OD2 3.38Å; K195-D233 HydrophobicContact CG-CB 4.06Å; K195-D233 WeakPolarHBondContact CG-OD2 3.43Å; K195-D233 IonicContact NZ-OD2 2.88Å; F196-D233 PolarHBondContact N-O 2.9Å; D233-G235 VanDerWaalsContact C-N 3.32Å; D233-G235 PolarHBondContact OD1-N 3.43Å; D233-I269 WeakPolarHBondContact CA-O 3.45Å; D233-I269 HydrophobicContact CB-CD1 3.91Å; D233-I269 HydrophobicContact CB-CG1 3.62Å
234I97.2Very high94.7Very high0 Ų044.9 Ų44.90%024%0.244CC..  trans-89.23.6-177.969169000113.6I62 F196 L232 F238 I252 V268 I269 A270I62-I234 HydrophobicContact CD1-CD1 3.91Å; I62-I234 HydrophobicContact CG2-CD1 4.34Å; F196-I234 HydrophobicContact CE1-CB 4.37Å; F196-I234 HydrophobicContact CE1-CG2 4.1Å; F196-I234 HydrophobicContact CE2-CB 3.96Å; F196-I234 HydrophobicContact CE2-CG2 4.47Å; F196-I234 WeakPolarHBondContact CE2-O 3.09Å; F196-I234 HydrophobicContact CZ-CB 3.66Å; F196-I234 HydrophobicContact CZ-CG2 3.68Å; F196-I234 CarbonylContact O-C 3.56Å; L232-I234 HydrophobicContact CD2-CG2 4.31Å; L232-I234 HydrophobicContact CG-CG2 4.22Å; I234-F238 HydrophobicContact CD1-CZ 3.98Å; I234-I252 HydrophobicContact CD1-CD1 3.65Å; I234-V268 HydrophobicContact CG2-CG1 3.94Å; I234-I269 WeakPolarHBondContact CG1-O 3.31Å; I234-I269 PolarHBondContact N-O 3.33Å; I234-A270 HydrophobicContact CD1-CB 4.1Å; I234-A270 HydrophobicContact CG1-CB 3.68Å
235G95.1Very high94.6Very high0 Ų038.6 Ų38.60%022%0.215CC..  trans76.2-159.1178.200000113.3F196 D233 F238 E271F196-G235 WeakPolarHBondContact O-CA 3.37Å; F196-G235 PolarHBondContact O-N 2.89Å; F196-G235 VanDerWaalsContact O-N 3.17Å; D233-G235 VanDerWaalsContact C-N 3.32Å; D233-G235 PolarHBondContact OD1-N 3.43Å; G235-F238 WeakPolarHBondContact O-CE2 3.17Å; G235-E271 PolarHBondContact O-N 2.92Å
236G90.4Very high94.6Very high10 Ų1041.4 Ų41.410%0.10323%0.228CC..  trans-129.713.4-157.200000116.4H197 F238 E271H197-G236 PolarHBondContact ND1-N 2.8Å; G236-F238 PolarHBondContact O-N 3.38Å; G236-E271 WeakPolarHBondContact CA-O 3.47Å
237G87.3Confident94.5Very high1 Ų143.2 Ų43.21%0.0122%0.22CC..  trans-69.750.1-173.700000115.6V198 Q244V198-G237 WeakPolarHBondContact O-CA 3.03Å; V198-G237 PolarHBondContact O-N 3.31Å; G237-Q244 PolarHBondContact O-NE2 2.97Å
238F92.9Very high94.3Very high0 Ų041.9 Ų41.90%021%0.214CC..  trans-117.1117-176.1-55-75.5000109.9W55 M59 I234 G235 G236 G240 L245 V248 A270 P272 C274 Y275W55-F238 HydrophobicContact CH2-CD2 4.07Å; W55-F238 HydrophobicContact CH2-CE1 4.3Å; W55-F238 AromaticContact CH2-CE2 3.75Å; W55-F238 HydrophobicContact CH2-CE2 3.75Å; W55-F238 HydrophobicContact CH2-CG 4.49Å; W55-F238 AromaticContact CH2-CZ 3.86Å; W55-F238 HydrophobicContact CH2-CZ 3.86Å; W55-F238 HydrophobicContact CZ3-CD1 4.18Å; W55-F238 AromaticContact CZ3-CD2 3.95Å; W55-F238 HydrophobicContact CZ3-CD2 3.95Å; W55-F238 HydrophobicContact CZ3-CE1 4.29Å; W55-F238 HydrophobicContact CZ3-CE2 4.08Å; W55-F238 HydrophobicContact CZ3-CG 4Å; W55-F238 HydrophobicContact CZ3-CZ 4.24Å; M59-F238 HydrophobicContact CE-CD1 4.33Å; M59-F238 HydrophobicContact CE-CE1 3.41Å; M59-F238 VanDerWaalsContact CE-CE1 3.41Å; M59-F238 HydrophobicContact CE-CZ 3.87Å; I234-F238 HydrophobicContact CD1-CZ 3.98Å; G235-F238 WeakPolarHBondContact O-CE2 3.17Å; G236-F238 PolarHBondContact O-N 3.38Å; F238-G240 VanDerWaalsContact C-N 3.32Å; F238-G240 PolarHBondContact O-N 3.36Å; F238-L245 HydrophobicContact CD1-CD1 3.74Å; F238-L245 HydrophobicContact CE1-CD1 4.17Å; F238-L245 HydrophobicContact CG-CD1 4.47Å; F238-V248 HydrophobicContact CE1-CB 4.46Å; F238-V248 HydrophobicContact CE1-CG1 3.88Å; F238-A270 HydrophobicContact CE2-CB 3.99Å; F238-A270 HydrophobicContact CZ-CB 4.45Å; F238-P272 HydrophobicContact CD2-CB 3.97Å; F238-C274 PolarHBondContact O-SG 2.88Å; F238-Y275 HydrophobicContact CB-CD2 4.02Å; F238-Y275 HydrophobicContact CB-CG 4.23Å; F238-Y275 PolarHBondContact O-N 3.47Å
239T90.2Very high94.3Very high54 Ų5434.4 Ų34.433%0.33118%0.183SC..  trans-75.9-20-171.358.40000113.8S241 Q244T239-S241 WeakPolarHBondContact OG1-CB 3.36Å; T239-S241 PolarHBondContact OG1-N 3.03Å; T239-Q244 HydrophobicContact CG2-CG 4.3Å; T239-Q244 PolarHBondContact OG1-OE1 2.98Å
240G88.9Confident94.2Very high11 Ų1141.8 Ų41.811%0.11321%0.21CC..SBendtrans99.8-11.1-167.200000113.2K51 F238K51-G240 PolarHBondContact NZ-O 3.32Å; F238-G240 VanDerWaalsContact C-N 3.32Å; F238-G240 PolarHBondContact O-N 3.36Å
241S91.1Very high94Very high51 Ų5139.7 Ų39.736%0.35720%0.199SC..  trans-73.5137.2173.5174.80000111.5T239 L243 Q244 L245T239-S241 WeakPolarHBondContact OG1-CB 3.36Å; T239-S241 PolarHBondContact OG1-N 3.03Å; S241-L243 PolarHBondContact OG-N 2.96Å; S241-Q244 PolarHBondContact O-N 2.9Å; S241-L245 PolarHBondContact O-N 3.04Å; S241-L245 VanDerWaalsContact O-N 3.09Å
242E91.9Very high93.9Very high107 Ų10738.7 Ų38.750%0.520%0.195SC..Hα-helixtrans-64.1-46.9174.2-174.8161.3-150.200112.7Q244 L245 E246E242-Q244 VanDerWaalsContact C-N 3.25Å; E242-Q244 PolarHBondContact O-N 3.38Å; E242-L245 WeakPolarHBondContact O-CB 3.37Å; E242-L245 PolarHBondContact O-N 3.45Å; E242-L245 VanDerWaalsContact O-N 3.11Å; E242-E246 HydrophobicContact CG-CG 4.5Å; E242-E246 WeakPolarHBondContact O-CG 3.42Å; E242-E246 PolarHBondContact O-N 2.96Å
243L93.4Very high93.7Very high120 Ų12042.4 Ų42.463%0.62821%0.208SC*.Hα-helixtrans-56-44.3177.3-64.6173.3000111.1S241 E246 E247S241-L243 PolarHBondContact OG-N 2.96Å; L243-E246 PolarHBondContact O-N 3.41Å; L243-E247 WeakPolarHBondContact O-CB 3.22Å; L243-E247 VanDerWaalsContact O-CG 3.26Å; L243-E247 WeakPolarHBondContact O-CG 3.27Å; L243-E247 PolarHBondContact O-N 3.34Å
244Q93.9Very high93.6Very high29 Ų2945.9 Ų45.914%0.13623%0.231CC..Hα-helixtrans-66.6-40.1179.8-170.2-106.8-0.500111.9G237 T239 S241 E242 E247 V248G237-Q244 PolarHBondContact O-NE2 2.97Å; T239-Q244 HydrophobicContact CG2-CG 4.3Å; T239-Q244 PolarHBondContact OG1-OE1 2.98Å; S241-Q244 PolarHBondContact O-N 2.9Å; E242-Q244 VanDerWaalsContact C-N 3.25Å; E242-Q244 PolarHBondContact O-N 3.38Å; Q244-E247 PolarHBondContact O-N 3.03Å; Q244-V248 VanDerWaalsContact O-CG2 3.29Å; Q244-V248 WeakPolarHBondContact O-CG2 3.3Å; Q244-V248 PolarHBondContact O-N 2.91Å
245L95.4Very high93.6Very high0 Ų047.3 Ų47.30%024%0.239CC..Hα-helixtrans-63-44.3176.5-170.372000111.5Q54 W55 V58 M59 F238 S241 E242 N249 Y275Q54-L245 HydrophobicContact CG-CD2 4.34Å; W55-L245 HydrophobicContact CE3-CD1 3.88Å; W55-L245 HydrophobicContact CZ3-CD1 3.75Å; V58-L245 HydrophobicContact CB-CD2 3.78Å; V58-L245 HydrophobicContact CB-CG 4.21Å; V58-L245 HydrophobicContact CG1-CD2 4.05Å; V58-L245 HydrophobicContact CG1-CG 3.9Å; V58-L245 HydrophobicContact CG2-CD2 4.05Å; M59-L245 HydrophobicContact CE-CD1 3.87Å; M59-L245 HydrophobicContact CG-CD1 3.85Å; M59-L245 HydrophobicContact CG-CD2 4.47Å; M59-L245 HydrophobicContact CG-CG 4.2Å; F238-L245 HydrophobicContact CD1-CD1 3.74Å; F238-L245 HydrophobicContact CE1-CD1 4.17Å; F238-L245 HydrophobicContact CG-CD1 4.47Å; S241-L245 PolarHBondContact O-N 3.04Å; S241-L245 VanDerWaalsContact O-N 3.09Å; E242-L245 WeakPolarHBondContact O-CB 3.37Å; E242-L245 PolarHBondContact O-N 3.45Å; E242-L245 VanDerWaalsContact O-N 3.11Å; L245-N249 VanDerWaalsContact O-CB 3.28Å; L245-N249 WeakPolarHBondContact O-CB 3.42Å; L245-N249 PolarHBondContact O-N 3.26Å; L245-Y275 HydrophobicContact CD1-CE2 4.14Å; L245-Y275 HydrophobicContact CD2-CE2 3.93Å; L245-Y275 HydrophobicContact CG-CE2 4.47Å
246E95.6Very high93.6Very high93 Ų9347.8 Ų47.844%0.43524%0.241SC..Hα-helixtrans-65.2-43.3177.4-70.4-178.6162.500112.4V58 E242 L243 N249 R250V58-E246 HydrophobicContact CG1-CG 4.4Å; V58-E246 HydrophobicContact CG2-CG 4.37Å; E242-E246 HydrophobicContact CG-CG 4.5Å; E242-E246 WeakPolarHBondContact O-CG 3.42Å; E242-E246 PolarHBondContact O-N 2.96Å; L243-E246 PolarHBondContact O-N 3.41Å; E246-N249 PolarHBondContact O-N 2.87Å; E246-R250 WeakPolarHBondContact O-CB 3.2Å; E246-R250 PolarHBondContact O-N 3.14Å
247E94.9Very high93.9Very high100 Ų10051.2 Ų51.247%0.46726%0.257SS..Hα-helixtrans-60.8-45.7177-78.3179.2156.400111.9L205 L243 Q244 R250 V251L205-E247 HydrophobicContact CD1-CB 4.32Å; L243-E247 WeakPolarHBondContact O-CB 3.22Å; L243-E247 VanDerWaalsContact O-CG 3.26Å; L243-E247 WeakPolarHBondContact O-CG 3.27Å; L243-E247 PolarHBondContact O-N 3.34Å; Q244-E247 PolarHBondContact O-N 3.03Å; E247-R250 PolarHBondContact O-N 2.87Å; E247-V251 PolarHBondContact O-N 2.91Å
248V94.8Very high94.3Very high2 Ų256.2 Ų56.21%0.01229%0.287CS..Hα-helixtrans-63.6-48.8175.5173.80000110M59 L205 Y208 F238 Q244 R250 V251 I252M59-V248 HydrophobicContact CE-CG1 4.34Å; L205-V248 HydrophobicContact CD2-CG2 4.05Å; Y208-V248 HydrophobicContact CE1-CG1 4.26Å; Y208-V248 HydrophobicContact CE2-CG1 4.14Å; Y208-V248 HydrophobicContact CE2-CG2 4.16Å; F238-V248 HydrophobicContact CE1-CB 4.46Å; F238-V248 HydrophobicContact CE1-CG1 3.88Å; Q244-V248 VanDerWaalsContact O-CG2 3.29Å; Q244-V248 WeakPolarHBondContact O-CG2 3.3Å; Q244-V248 PolarHBondContact O-N 2.91Å; V248-R250 VanDerWaalsContact C-N 3.3Å; V248-R250 PolarHBondContact O-N 2.91Å; V248-V251 PolarHBondContact O-N 3.11Å; V248-I252 HydrophobicContact CG1-CD1 4.25Å; V248-I252 HydrophobicContact CG1-CG2 4.04Å; V248-I252 WeakPolarHBondContact O-CG1 3.06Å; V248-I252 PolarHBondContact O-N 3.18Å
249N95.6Very high94.6Very high30 Ų3059.8 Ų59.816%0.1630%0.301CS..Hα-helixtrans-57-42.3179.3-173.342.2000112.4V58 M59 L245 E246 V251 I252 R253V58-N249 HydrophobicContact CG1-CB 3.7Å; V58-N249 PolarHBondContact O-ND2 3.34Å; V58-N249 PolarHBondContact O-OD1 3.45Å; M59-N249 HydrophobicContact CE-CB 4.47Å; M59-N249 HydrophobicContact SD-CB 3.74Å; L245-N249 VanDerWaalsContact O-CB 3.28Å; L245-N249 WeakPolarHBondContact O-CB 3.42Å; L245-N249 PolarHBondContact O-N 3.26Å; E246-N249 PolarHBondContact O-N 2.87Å; N249-V251 PolarHBondContact O-N 2.85Å; N249-I252 PolarHBondContact O-N 3.16Å; N249-R253 WeakPolarHBondContact O-CB 3.46Å; N249-R253 PolarHBondContact O-N 2.99Å
250R95.8Very high94.9Very high179 Ų17957.7 Ų57.768%0.67529%0.287SS*.Hα-helixtrans-57.7-31.8177.6-171.9179.970.4174.6-1.5112.6E246 E247 V248 P254E246-R250 WeakPolarHBondContact O-CB 3.2Å; E246-R250 PolarHBondContact O-N 3.14Å; E247-R250 PolarHBondContact O-N 2.87Å; V248-R250 VanDerWaalsContact C-N 3.3Å; V248-R250 PolarHBondContact O-N 2.91Å; R250-P254 WeakPolarHBondContact O-CD 3.4Å
251V94.9Very high95.2Very high26 Ų2659.1 Ų59.116%0.15830%0.295CS..Hα-helixtrans-87.3-46.9179.4174.30000111.8L205 I209 E247 V248 N249 L255L205-V251 HydrophobicContact CB-CG1 4.43Å; L205-V251 HydrophobicContact CB-CG2 3.98Å; L205-V251 HydrophobicContact CD1-CG2 3.78Å; L205-V251 HydrophobicContact CG-CG2 4.43Å; I209-V251 HydrophobicContact CD1-CG1 3.91Å; I209-V251 HydrophobicContact CG1-CG1 3.61Å; E247-V251 PolarHBondContact O-N 2.91Å; V248-V251 PolarHBondContact O-N 3.11Å; N249-V251 PolarHBondContact O-N 2.85Å; V251-L255 WeakPolarHBondContact O-CD1 3.36Å
252I95.5Very high95.2Very high0 Ų064.4 Ų64.40%031%0.312CS..Hα-helixtrans-75.7-34.2-174.468.7172.8000112.5M59 I62 Y208 I212 I234 V248 N249 L255 L256M59-I252 HydrophobicContact CE-CD1 3.73Å; M59-I252 HydrophobicContact SD-CD1 4.18Å; I62-I252 HydrophobicContact CD1-CD1 3.74Å; Y208-I252 HydrophobicContact CD1-CG2 3.81Å; Y208-I252 HydrophobicContact CG-CG2 3.99Å; I212-I252 HydrophobicContact CD1-CB 3.8Å; I212-I252 HydrophobicContact CD1-CG2 3.8Å; I234-I252 HydrophobicContact CD1-CD1 3.65Å; V248-I252 HydrophobicContact CG1-CD1 4.25Å; V248-I252 HydrophobicContact CG1-CG2 4.04Å; V248-I252 WeakPolarHBondContact O-CG1 3.06Å; V248-I252 PolarHBondContact O-N 3.18Å; N249-I252 PolarHBondContact O-N 3.16Å; I252-L255 WeakPolarHBondContact O-CB 3.48Å; I252-L255 PolarHBondContact O-N 2.82Å; I252-L255 VanDerWaalsContact O-N 3.14Å; I252-L256 HydrophobicContact CD1-CD1 4.33Å; I252-L256 HydrophobicContact CG1-CD1 4.38Å; I252-L256 WeakPolarHBondContact O-CG 3.42Å; I252-L256 PolarHBondContact O-N 3.03Å
253R95.3Very high95.3Very high77 Ų7767.4 Ų67.429%0.29133%0.325SS..Hα-helixtrans-62.6-48.6-170.4-179.957.6178.5-88.2-5.6113.3N249 L255 L256 D257N249-R253 WeakPolarHBondContact O-CB 3.46Å; N249-R253 PolarHBondContact O-N 2.99Å; R253-L255 PolarHBondContact O-N 2.8Å; R253-L256 PolarHBondContact O-N 3.49Å; R253-D257 IonicContact CZ-OD1 3.38Å; R253-D257 IonicContact NE-OD1 2.8Å; R253-D257 PolarHBondContact NE-OD1 2.87Å; R253-D257 IonicContact NE-OD2 2.66Å; R253-D257 PolarHBondContact NE-OD2 3.48Å; R253-D257 PolarHBondContact O-N 2.93Å
254P96.1Very high95.3Very high74 Ų7464.1 Ų64.148%0.48131%0.313SS..Hα-helixtrans-59.5-34.1175.9-23.534.8000113R250 V258R250-P254 WeakPolarHBondContact O-CD 3.4Å; P254-V258 VanDerWaalsContact O-CG2 3.31Å; P254-V258 WeakPolarHBondContact O-CG2 3.34Å; P254-V258 PolarHBondContact O-N 3.38Å
255L96.1Very high95.3Very high30 Ų3065 Ų6516%0.15733%0.329CS..Hα-helixtrans-72.7-41.8179.2-60.8171.6000111.8I209 I212 V251 I252 R253 D257 V258 Y259I209-L255 HydrophobicContact CB-CD1 3.98Å; I209-L255 HydrophobicContact CG1-CD1 3.82Å; I209-L255 HydrophobicContact CG2-CD1 3.9Å; I209-L255 HydrophobicContact CG2-CD2 4.3Å; I212-L255 HydrophobicContact CD1-CB 4.23Å; I212-L255 HydrophobicContact CD1-CD1 4.13Å; I212-L255 HydrophobicContact CG2-CB 4.06Å; V251-L255 WeakPolarHBondContact O-CD1 3.36Å; I252-L255 WeakPolarHBondContact O-CB 3.48Å; I252-L255 PolarHBondContact O-N 2.82Å; I252-L255 VanDerWaalsContact O-N 3.14Å; R253-L255 PolarHBondContact O-N 2.8Å; L255-D257 VanDerWaalsContact C-N 3.35Å; L255-V258 PolarHBondContact O-N 2.86Å; L255-Y259 HydrophobicContact CB-CD2 4.27Å; L255-Y259 HydrophobicContact CD2-CE2 4.08Å; L255-Y259 WeakPolarHBondContact O-CB 3.48Å; L255-Y259 WeakPolarHBondContact O-CD2 3.07Å; L255-Y259 PolarHBondContact O-N 3.5Å
256L96.6Very high95.4Very high9 Ų965.9 Ų65.95%0.04733%0.334CS..Hα-helixtrans-62.8-42.9174.7-67.6177.6000110.9I62 I212 L232 I252 R253 V258 F260 V268I62-L256 HydrophobicContact CD1-CD1 3.93Å; I62-L256 HydrophobicContact CG1-CD1 4.45Å; I212-L256 HydrophobicContact CD1-CD2 4.43Å; I212-L256 HydrophobicContact CG2-CD2 4.42Å; L232-L256 HydrophobicContact CD2-CD2 3.74Å; I252-L256 HydrophobicContact CD1-CD1 4.33Å; I252-L256 HydrophobicContact CG1-CD1 4.38Å; I252-L256 WeakPolarHBondContact O-CG 3.42Å; I252-L256 PolarHBondContact O-N 3.03Å; R253-L256 PolarHBondContact O-N 3.49Å; L256-V258 PolarHBondContact O-N 3.43Å; L256-F260 HydrophobicContact CD2-CD2 4.08Å; L256-F260 CarbonylContact O-C 3.55Å; L256-F260 VanDerWaalsContact O-CA 3.26Å; L256-F260 WeakPolarHBondContact O-CA 3.13Å; L256-F260 PolarHBondContact O-N 3.24Å; L256-F260 VanDerWaalsContact O-O 3.13Å; L256-V268 HydrophobicContact CD1-CG1 4.13Å; L256-V268 HydrophobicContact CD2-CG1 4.28Å; L256-V268 HydrophobicContact CD2-CG2 4.28Å
257D95.4Very high95.5Very high82 Ų8266 Ų6644%0.43934%0.338SS..Hα-helixtrans-62.8-29.2178-69.3-21000112.1R253 L255 P261R253-D257 IonicContact CZ-OD1 3.38Å; R253-D257 IonicContact NE-OD1 2.8Å; R253-D257 PolarHBondContact NE-OD1 2.87Å; R253-D257 IonicContact NE-OD2 2.66Å; R253-D257 PolarHBondContact NE-OD2 3.48Å; R253-D257 PolarHBondContact O-N 2.93Å; L255-D257 VanDerWaalsContact C-N 3.35Å; D257-P261 WeakPolarHBondContact O-CB 3.4Å
258V96.9Very high95.6Very high106 Ų10662 Ų6264%0.64232%0.32SS*.Hα-helixtrans-86.5-49.5178.2171.60000112.6P254 L255 L256P254-V258 VanDerWaalsContact O-CG2 3.31Å; P254-V258 WeakPolarHBondContact O-CG2 3.34Å; P254-V258 PolarHBondContact O-N 3.38Å; L255-V258 PolarHBondContact O-N 2.86Å; L256-V258 PolarHBondContact O-N 3.43Å
259Y97.5Very high95.8Very high76 Ų7662 Ų6230%0.29832%0.321SS..Hα-helixtrans-88.4-26.1-172-67.2-46.2000114I212 R216 L255I212-Y259 HydrophobicContact CG2-CD2 3.83Å; R216-Y259 HydrophobicContact CB-CD1 4.2Å; R216-Y259 HydrophobicContact CB-CG 4.15Å; R216-Y259 WeakPolarHBondContact CD-O 3.42Å; R216-Y259 HydrophobicContact CG-CD1 3.74Å; R216-Y259 HydrophobicContact CG-CE1 4.4Å; R216-Y259 HydrophobicContact CG-CG 4.1Å; R216-Y259 PolarHBondContact NH1-O 3.5Å; L255-Y259 HydrophobicContact CB-CD2 4.27Å; L255-Y259 HydrophobicContact CD2-CE2 4.08Å; L255-Y259 WeakPolarHBondContact O-CB 3.48Å; L255-Y259 WeakPolarHBondContact O-CD2 3.07Å; L255-Y259 PolarHBondContact O-N 3.5Å
260F96.8Very high95.9Very high9 Ų960.6 Ų60.64%0.03931%0.313CS..SBendtrans-137.555.8-176.2-56.6-76.6000110.9I212 A215 R216 F219 L232 L256 V266I212-F260 HydrophobicContact CG2-CD2 4.29Å; I212-F260 HydrophobicContact CG2-CE2 3.9Å; A215-F260 HydrophobicContact CB-CZ 4.24Å; R216-F260 HydrophobicContact CB-CE2 4.38Å; R216-F260 HydrophobicContact CB-CZ 4.07Å; F219-F260 HydrophobicContact CB-CE1 4.42Å; F219-F260 HydrophobicContact CD1-CD1 4.45Å; F219-F260 AromaticContact CD1-CE1 3.84Å; F219-F260 HydrophobicContact CD1-CE1 3.84Å; F219-F260 AromaticContact CD2-CE1 3.76Å; F219-F260 HydrophobicContact CD2-CE1 3.76Å; F219-F260 HydrophobicContact CD2-CZ 4.16Å; F219-F260 HydrophobicContact CE1-CD1 4.28Å; F219-F260 AromaticContact CE1-CE1 3.9Å; F219-F260 HydrophobicContact CE1-CE1 3.9Å; F219-F260 AromaticContact CE2-CE1 3.79Å; F219-F260 HydrophobicContact CE2-CE1 3.79Å; F219-F260 HydrophobicContact CE2-CZ 4.25Å; F219-F260 AromaticContact CG-CE1 3.76Å; F219-F260 HydrophobicContact CG-CE1 3.76Å; F219-F260 HydrophobicContact CG-CZ 4.48Å; F219-F260 HydrophobicContact CZ-CD1 4.41Å; F219-F260 AromaticContact CZ-CE1 3.86Å; F219-F260 HydrophobicContact CZ-CE1 3.86Å; L232-F260 HydrophobicContact CD2-CD1 4.49Å; L232-F260 HydrophobicContact CD2-CD2 3.62Å; L232-F260 HydrophobicContact CD2-CE1 4.46Å; L232-F260 HydrophobicContact CD2-CE2 3.58Å; L232-F260 HydrophobicContact CD2-CG 4.09Å; L232-F260 HydrophobicContact CD2-CZ 4.01Å; L256-F260 HydrophobicContact CD2-CD2 4.08Å; L256-F260 CarbonylContact O-C 3.55Å; L256-F260 VanDerWaalsContact O-CA 3.26Å; L256-F260 WeakPolarHBondContact O-CA 3.13Å; L256-F260 PolarHBondContact O-N 3.24Å; L256-F260 VanDerWaalsContact O-O 3.13Å; F260-V266 HydrophobicContact CD1-CB 4.38Å; F260-V266 HydrophobicContact CD1-CG1 4.07Å; F260-V266 HydrophobicContact CD1-CG2 4.24Å
261P95.6Very high96Very high42 Ų4252.8 Ų52.827%0.27328%0.284SS..  trans-61.6155.9-177.929.6-37.5000110.8D257 E263 S264D257-P261 WeakPolarHBondContact O-CB 3.4Å; P261-E263 WeakPolarHBondContact CB-OE2 3.23Å; P261-E263 PolarHBondContact O-N 3.21Å; P261-S264 VanDerWaalsContact O-CB 3.23Å; P261-S264 WeakPolarHBondContact O-CB 3.47Å; P261-S264 PolarHBondContact O-N 3.47Å; P261-S264 PolarHBondContact O-OG 3.35Å
262K91.6Very high96.1Very high162 Ų16251.6 Ų51.670%0.70428%0.277SS*.G310 helixtrans-55.3-32.9-175.3-71.1-175177.3-177.40113.1S264 G265K262-S264 PolarHBondContact O-N 3.28Å; K262-G265 PolarHBondContact O-N 3.45Å
263E93.2Very high96Very high169 Ų16951.7 Ų51.779%0.7928%0.278SS*.G310 helixtrans-66.6-20.5179-59.473.8-161.100112.8P261 G265P261-E263 WeakPolarHBondContact CB-OE2 3.23Å; P261-E263 PolarHBondContact O-N 3.21Å; E263-G265 PolarHBondContact O-N 3.33Å
264S93.4Very high95.9Very high52 Ų5249.4 Ų49.436%0.36427%0.273SS..G310 helixtrans-69.4-17.1175.270.90000113.1P261 K262 V266P261-S264 VanDerWaalsContact O-CB 3.23Å; P261-S264 WeakPolarHBondContact O-CB 3.47Å; P261-S264 PolarHBondContact O-N 3.47Å; P261-S264 PolarHBondContact O-OG 3.35Å; K262-S264 PolarHBondContact O-N 3.28Å; S264-V266 PolarHBondContact O-N 3.25Å; S264-V266 WeakPolarHBondContact OG-CG2 3.44Å; S264-V266 PolarHBondContact OG-N 2.84Å
265G94.8Very high95.9Very high46 Ų4645.9 Ų45.947%0.47425%0.25SS..THydrogen-bonded Turntrans70.513.8-17700000114.3K262 E263K262-G265 PolarHBondContact O-N 3.45Å; E263-G265 PolarHBondContact O-N 3.33Å
266V97.6Very high95.9Very high19 Ų1944.4 Ų44.412%0.11524%0.243CC..PPolyproline II helixtrans-79.6123.2176.4179.30000110.1F219 L232 F260 S264F219-V266 HydrophobicContact CD1-CG2 4.39Å; F219-V266 HydrophobicContact CE1-CG1 3.97Å; F219-V266 HydrophobicContact CE1-CG2 3.67Å; F219-V266 HydrophobicContact CZ-CG1 3.98Å; F219-V266 HydrophobicContact CZ-CG2 4.5Å; L232-V266 HydrophobicContact CB-CG1 4.05Å; F260-V266 HydrophobicContact CD1-CB 4.38Å; F260-V266 HydrophobicContact CD1-CG1 4.07Å; F260-V266 HydrophobicContact CD1-CG2 4.24Å; S264-V266 PolarHBondContact O-N 3.25Å; S264-V266 WeakPolarHBondContact OG-CG2 3.44Å; S264-V266 PolarHBondContact OG-N 2.84Å
267N96.9Very high95.9Very high96 Ų9644 Ų4451%0.51324%0.241SC..EExtended strand (participates in β ladder)trans-84.5117.3172-62.8-56.8000109.3N230 M231 L232N230-N267 PolarHBondContact O-N 3.08Å; M231-N267 WeakPolarHBondContact CA-O 3.15Å; L232-N267 PolarHBondContact N-O 3.14Å
268V98.1Very high95.7Very high15 Ų1541.4 Ų41.49%0.09123%0.229CC..EExtended strand (participates in β ladder)trans-89.3128.4174-168.90000108.7I62 K63 L232 I234 L256I62-V268 WeakPolarHBondContact CA-O 3.48Å; I62-V268 HydrophobicContact CD1-CG1 4.42Å; I62-V268 HydrophobicContact CG1-CB 4.36Å; I62-V268 HydrophobicContact CG1-CG1 4.08Å; I62-V268 HydrophobicContact CG2-CG1 4.19Å; K63-V268 PolarHBondContact N-O 2.86Å; L232-V268 HydrophobicContact CD2-CG1 4.46Å; L232-V268 CarbonylContact O-C 3.55Å; L232-V268 WeakPolarHBondContact O-CA 3.07Å; I234-V268 HydrophobicContact CG2-CG1 3.94Å; L256-V268 HydrophobicContact CD1-CG1 4.13Å; L256-V268 HydrophobicContact CD2-CG1 4.28Å; L256-V268 HydrophobicContact CD2-CG2 4.28Å
269I98.5Very high95.6Very high4 Ų437.9 Ų37.92%0.02121%0.209CC..EExtended strand (participates in β ladder)trans-124.5161.6177.271.7171.9000109.8K63 F65 I109 M231 L232 D233 I234K63-I269 HydrophobicContact CB-CG2 4.33Å; K63-I269 CarbonylContact O-C 3.6Å; K63-I269 WeakPolarHBondContact O-CA 3.41Å; K63-I269 WeakPolarHBondContact O-CB 3.14Å; F65-I269 HydrophobicContact CD2-CB 3.97Å; F65-I269 HydrophobicContact CD2-CD1 4.14Å; F65-I269 HydrophobicContact CD2-CG2 4.13Å; F65-I269 HydrophobicContact CE2-CB 4.13Å; F65-I269 HydrophobicContact CE2-CD1 4.3Å; F65-I269 HydrophobicContact CE2-CG2 3.76Å; I109-I269 HydrophobicContact CD1-CD1 3.15Å; M231-I269 HydrophobicContact CG-CD1 4.25Å; M231-I269 HydrophobicContact CG-CG1 4.5Å; M231-I269 HydrophobicContact SD-CD1 3.97Å; L232-I269 PolarHBondContact O-N 3.08Å; D233-I269 WeakPolarHBondContact CA-O 3.45Å; D233-I269 HydrophobicContact CB-CD1 3.91Å; D233-I269 HydrophobicContact CB-CG1 3.62Å; I234-I269 WeakPolarHBondContact CG1-O 3.31Å; I234-I269 PolarHBondContact N-O 3.33Å
270A98.1Very high95.5Very high0 Ų034.3 Ų34.30%020%0.195CC..EExtended strand (participates in β ladder)trans-137.8163.2172.700000110.2W55 I62 K63 P64 F65 I234 F238 P272W55-A270 HydrophobicContact CH2-CB 3.59Å; W55-A270 HydrophobicContact CZ2-CB 3.65Å; I62-A270 HydrophobicContact CG2-CB 3.72Å; K63-A270 PolarHBondContact O-N 3.4Å; P64-A270 CarbonylContact C-O 3.5Å; F65-A270 PolarHBondContact N-O 3.38Å; I234-A270 HydrophobicContact CD1-CB 4.1Å; I234-A270 HydrophobicContact CG1-CB 3.68Å; F238-A270 HydrophobicContact CE2-CB 3.99Å; F238-A270 HydrophobicContact CZ-CB 4.45Å; A270-P272 WeakPolarHBondContact O-CD 3.4Å
271E97.8Very high95.5Very high15 Ų1534 Ų347%0.0719%0.194CC..  trans-11554.5-179.8-67.8-175.3172.800113.6F65 P67 A88 T111 K195 G235 G236 G273F65-E271 VanDerWaalsContact O-CA 3.25Å; F65-E271 WeakPolarHBondContact O-CA 3.39Å; P67-E271 HydrophobicContact CG-CB 3.99Å; P67-E271 VanDerWaalsContact CG-O 3.24Å; P67-E271 WeakPolarHBondContact CG-O 3.47Å; A88-E271 HydrophobicContact CB-CG 4.18Å; T111-E271 WeakPolarHBondContact CG2-OE1 3.43Å; K195-E271 IonicContact NZ-OE1 2.68Å; K195-E271 PolarHBondContact NZ-OE1 3.34Å; K195-E271 IonicContact NZ-OE2 2.68Å; K195-E271 PolarHBondContact NZ-OE2 3.23Å; G235-E271 PolarHBondContact O-N 2.92Å; G236-E271 WeakPolarHBondContact CA-O 3.47Å; E271-G273 PolarHBondContact O-N 3.06Å; E271-G273 VanDerWaalsContact O-N 3.13Å
272P96.6Very high95.5Very high0 Ų032.1 Ų32.10%018%0.182CC..  trans-68.2110.9-177.929.5-35.6000111.4W55 P64 P67 F238 A270 Y275 Y276W55-P272 HydrophobicContact CE3-CB 4.33Å; W55-P272 HydrophobicContact CE3-CG 4.27Å; W55-P272 HydrophobicContact CH2-CB 4.24Å; W55-P272 HydrophobicContact CH2-CG 4Å; W55-P272 HydrophobicContact CZ2-CG 4.39Å; W55-P272 HydrophobicContact CZ3-CB 3.83Å; W55-P272 HydrophobicContact CZ3-CG 3.93Å; P64-P272 HydrophobicContact CB-CG 3.66Å; P67-P272 WeakPolarHBondContact CD-O 3.5Å; F238-P272 HydrophobicContact CD2-CB 3.97Å; A270-P272 WeakPolarHBondContact O-CD 3.4Å; P272-Y275 HydrophobicContact CB-CD1 4.09Å; P272-Y275 HydrophobicContact CB-CG 4.15Å; P272-Y276 HydrophobicContact CB-CD2 4.34Å; P272-Y276 HydrophobicContact CB-CE2 4.21Å; P272-Y276 HydrophobicContact CG-CD2 4.22Å; P272-Y276 HydrophobicContact CG-CE2 3.7Å; P272-Y276 WeakPolarHBondContact O-CD2 3.42Å
273G93.8Very high95.8Very high3 Ų324.4 Ų24.43%0.03115%0.148CC..SBendtrans-100.3-80.8178.600000112.9E271 Y275 Y276E271-G273 PolarHBondContact O-N 3.06Å; E271-G273 VanDerWaalsContact O-N 3.13Å; G273-Y275 PolarHBondContact O-N 2.74Å; G273-Y275 VanDerWaalsContact O-N 3.11Å; G273-Y276 PolarHBondContact O-N 3.37Å
274C91.6Very high95.9Very high28 Ų2816.5 Ų16.519%0.18911%0.112CC..Hα-helixtrans-55.1-30.5179.356.60000112.6F238 Y276 V277 S278 S387F238-C274 PolarHBondContact O-SG 2.88Å; C274-Y276 VanDerWaalsContact C-N 3.28Å; C274-Y276 PolarHBondContact O-N 3.02Å; C274-V277 PolarHBondContact O-N 2.91Å; C274-S278 WeakPolarHBondContact O-CB 3.4Å; C274-S278 PolarHBondContact O-N 3.39Å; C274-S387 WeakPolarHBondContact CB-OG 3.47Å
275Y96.3Very high96.1Very high0 Ų014 Ų140%09%0.094CC..Hα-helixtrans-44.6-47.8171.3176.6-95.9000114.3K51 W55 F238 L245 P272 G273K51-Y275 HydrophobicContact CB-CD1 4.49Å; K51-Y275 HydrophobicContact CB-CE1 3.89Å; K51-Y275 HydrophobicContact CD-CE1 4.14Å; K51-Y275 HydrophobicContact CD-CE2 4.24Å; K51-Y275 WeakPolarHBondContact CD-O 3.37Å; K51-Y275 WeakPolarHBondContact O-CE1 3.37Å; K51-Y275 PolarHBondContact O-OH 3.26Å; W55-Y275 HydrophobicContact CB-CE1 4.11Å; W55-Y275 HydrophobicContact CE3-CD1 4.24Å; W55-Y275 AromaticContact CE3-CE1 3.91Å; W55-Y275 HydrophobicContact CE3-CE1 3.91Å; W55-Y275 PolarHBondContact N-OH 3.2Å; F238-Y275 HydrophobicContact CB-CD2 4.02Å; F238-Y275 HydrophobicContact CB-CG 4.23Å; F238-Y275 PolarHBondContact O-N 3.47Å; L245-Y275 HydrophobicContact CD1-CE2 4.14Å; L245-Y275 HydrophobicContact CD2-CE2 3.93Å; L245-Y275 HydrophobicContact CG-CE2 4.47Å; P272-Y275 HydrophobicContact CB-CD1 4.09Å; P272-Y275 HydrophobicContact CB-CG 4.15Å; G273-Y275 PolarHBondContact O-N 2.74Å; G273-Y275 VanDerWaalsContact O-N 3.11Å
276Y96.9Very high96.2Very high0 Ų012.1 Ų12.10%07%0.073CC..Hα-helixtrans-78-46.6-176.4-83.9-69000112.1L48 K51 N52 P64 Y66 L80 I85 P272 G273 C274L48-Y276 VanDerWaalsContact CD2-O 3.23Å; L48-Y276 WeakPolarHBondContact CD2-O 3.39Å; K51-Y276 HydrophobicContact CB-CD1 3.74Å; K51-Y276 HydrophobicContact CB-CE1 4.02Å; N52-Y276 HydrophobicContact CB-CE1 3.88Å; N52-Y276 PolarHBondContact OD1-OH 3.3Å; P64-Y276 HydrophobicContact CB-CE2 4.24Å; Y66-Y276 HydrophobicContact CD2-CD2 4.1Å; L80-Y276 HydrophobicContact CD2-CD1 3.78Å; L80-Y276 HydrophobicContact CD2-CE1 4.15Å; L80-Y276 HydrophobicContact CD2-CG 4.05Å; I85-Y276 HydrophobicContact CD1-CE1 3.84Å; I85-Y276 HydrophobicContact CD1-CE2 4.12Å; I85-Y276 WeakPolarHBondContact CD1-OH 3.3Å; P272-Y276 HydrophobicContact CB-CD2 4.34Å; P272-Y276 HydrophobicContact CB-CE2 4.21Å; P272-Y276 HydrophobicContact CG-CD2 4.22Å; P272-Y276 HydrophobicContact CG-CE2 3.7Å; P272-Y276 WeakPolarHBondContact O-CD2 3.42Å; G273-Y276 PolarHBondContact O-N 3.37Å; C274-Y276 VanDerWaalsContact C-N 3.28Å; C274-Y276 PolarHBondContact O-N 3.02Å
277V95.8Very high96.1Very high0 Ų011.2 Ų11.20%07%0.068CC..Hα-helixtrans-105.2-22.8-160.6-64.50000114.2L48 Y66 C70 N71 V76 C274 S279 A280 G386L48-V277 HydrophobicContact CD2-CG1 3.96Å; Y66-V277 HydrophobicContact CE2-CG1 3.97Å; Y66-V277 HydrophobicContact CE2-CG2 4.39Å; Y66-V277 WeakPolarHBondContact OH-CG1 3.43Å; C70-V277 HydrophobicContact CB-CG2 4.32Å; N71-V277 HydrophobicContact CB-CB 4.24Å; N71-V277 HydrophobicContact CB-CG1 4.14Å; N71-V277 HydrophobicContact CB-CG2 4.02Å; V76-V277 HydrophobicContact CG1-CG1 3.69Å; V76-V277 HydrophobicContact CG2-CG1 4.48Å; C274-V277 PolarHBondContact O-N 2.91Å; V277-S279 PolarHBondContact O-N 3.45Å; V277-A280 WeakPolarHBondContact O-CB 3.45Å; V277-A280 PolarHBondContact O-N 3.48Å; V277-A280 VanDerWaalsContact O-N 3.08Å; V277-G386 WeakPolarHBondContact CG2-O 3.4Å; V277-G386 WeakPolarHBondContact O-CA 3.42Å
278S93.1Very high96.1Very high28 Ų2810.3 Ų10.320%0.1966%0.062CC..G310 helixtrans-52.4-60.4-169.6-176.20000111.8C274 A280 N384 M385 G386C274-S278 WeakPolarHBondContact O-CB 3.4Å; C274-S278 PolarHBondContact O-N 3.39Å; S278-A280 VanDerWaalsContact C-N 3.27Å; S278-A280 PolarHBondContact O-N 3.09Å; S278-N384 CarbonylContact O-C 3.6Å; S278-N384 WeakPolarHBondContact O-CA 3.32Å; S278-N384 PolarHBondContact OG-O 3.29Å; S278-M385 PolarHBondContact O-N 2.94Å; S278-G386 PolarHBondContact O-N 2.92Å; S278-G386 VanDerWaalsContact O-N 3.09Å
279S94.4Very high96Very high31 Ų3111.5 Ų11.522%0.2177%0.073CC..G310 helixtrans-80.70.1-178.764.10000115.1K47 V277 N384K47-S279 VanDerWaalsContact CD-O 3.29Å; K47-S279 WeakPolarHBondContact CD-O 3.39Å; K47-S279 PolarHBondContact NZ-O 3.37Å; V277-S279 PolarHBondContact O-N 3.45Å; S279-N384 VanDerWaalsContact CA-OD1 3.3Å; S279-N384 WeakPolarHBondContact CA-OD1 3.29Å; S279-N384 WeakPolarHBondContact CB-OD1 3.34Å
280A95.7Very high95.9Very high2 Ų213.9 Ų13.92%0.0178%0.084CC..G310 helixtrans-82.6-16.1178.600000112.5G43 D44 K47 L48 V277 S278G43-A280 CarbonylContact C-O 3.55Å; G43-A280 WeakPolarHBondContact CA-O 3.03Å; D44-A280 PolarHBondContact N-O 3.44Å; K47-A280 HydrophobicContact CB-CB 4.18Å; L48-A280 HydrophobicContact CD2-CB 3.86Å; V277-A280 WeakPolarHBondContact O-CB 3.45Å; V277-A280 PolarHBondContact O-N 3.48Å; V277-A280 VanDerWaalsContact O-N 3.08Å; S278-A280 VanDerWaalsContact C-N 3.27Å; S278-A280 PolarHBondContact O-N 3.09Å
281F95.8Very high95.6Very high1 Ų119.3 Ų19.30%0.00411%0.107CC..EExtended strand (participates in β ladder)trans-124136.1-178-67.6-101.3000112Y41 V42 N71 V76 N384 M385 L390 I404 Y406Y41-F281 HydrophobicContact CD1-CB 4.03Å; Y41-F281 HydrophobicContact CD1-CD1 4.23Å; Y41-F281 HydrophobicContact CE1-CB 4.37Å; V42-F281 WeakPolarHBondContact O-CA 3.49Å; N71-F281 WeakPolarHBondContact ND2-CE2 3.44Å; V76-F281 HydrophobicContact CG2-CE2 3.82Å; V76-F281 HydrophobicContact CG2-CZ 3.61Å; F281-N384 PolarHBondContact O-N 3.08Å; F281-M385 PolarHBondContact O-N 3.29Å; F281-L390 HydrophobicContact CD1-CD1 4.13Å; F281-L390 HydrophobicContact CE1-CD1 4.11Å; F281-I404 HydrophobicContact CE1-CG2 4.01Å; F281-Y406 AromaticContact CE1-CE1 3.93Å; F281-Y406 HydrophobicContact CE1-CE1 3.93Å; F281-Y406 HydrophobicContact CZ-CE1 4.02Å
282T96.4Very high95.2Very high4 Ų422.5 Ų22.53%0.02513%0.128CC..EExtended strand (participates in β ladder)trans-118.2134.3171.8-62.90000108.6I25 Y41 V42 I381 F382 D383I25-T282 HydrophobicContact CD1-CG2 3.68Å; Y41-T282 CarbonylContact C-O 3.57Å; Y41-T282 VanDerWaalsContact CA-O 3.32Å; Y41-T282 WeakPolarHBondContact CA-O 3.39Å; V42-T282 PolarHBondContact N-O 3.29Å; V42-T282 PolarHBondContact O-N 3.22Å; T282-I381 HydrophobicContact CG2-CG2 3.29Å; T282-F382 WeakPolarHBondContact CA-O 3.4Å; T282-D383 WeakPolarHBondContact CG2-OD1 3.46Å; T282-D383 PolarHBondContact OG1-OD1 3.41Å
283L96.4Very high94.3Very high0 Ų024.6 Ų24.60%014%0.14CC..EExtended strand (participates in β ladder)trans-104.6128.4179.3174.765.3000109.9Y41 V285 F325 I381 F382 M385 P402Y41-L283 HydrophobicContact CD1-CB 4.04Å; Y41-L283 HydrophobicContact CD1-CD1 4.36Å; Y41-L283 HydrophobicContact CD2-CD1 4.02Å; Y41-L283 HydrophobicContact CE1-CB 3.63Å; Y41-L283 HydrophobicContact CE1-CD1 4.1Å; Y41-L283 HydrophobicContact CE1-CG 4.32Å; Y41-L283 HydrophobicContact CE2-CD1 3.72Å; Y41-L283 HydrophobicContact CG-CD1 4.33Å; L283-V285 HydrophobicContact CD1-CG1 4.17Å; L283-V285 HydrophobicContact CD2-CG1 3.79Å; L283-V285 HydrophobicContact CG-CG1 3.74Å; L283-F325 HydrophobicContact CD2-CE2 3.72Å; L283-F325 HydrophobicContact CD2-CZ 3.69Å; L283-I381 CarbonylContact O-C 3.54Å; L283-I381 WeakPolarHBondContact O-CA 2.91Å; L283-F382 HydrophobicContact CB-CB 4.32Å; L283-F382 PolarHBondContact N-O 2.9Å; L283-F382 PolarHBondContact O-N 3.11Å; L283-M385 HydrophobicContact CB-CB 3.92Å; L283-M385 HydrophobicContact CB-CG 3.98Å; L283-M385 HydrophobicContact CD2-CE 3.73Å; L283-P402 HydrophobicContact CD1-CB 4.38Å; L283-P402 HydrophobicContact CD1-CG 4.31Å
284A97Very high92.9Very high2 Ų230.4 Ų30.42%0.01717%0.167CC..EExtended strand (participates in β ladder)trans-105.3127.1169.200000109.9A39 F40 W379 I381A39-A284 VanDerWaalsContact CA-O 3.26Å; A39-A284 WeakPolarHBondContact CA-O 3.5Å; F40-A284 HydrophobicContact CD1-CB 4.13Å; F40-A284 HydrophobicContact CD2-CB 4.33Å; F40-A284 HydrophobicContact CE1-CB 3.65Å; F40-A284 HydrophobicContact CE2-CB 3.88Å; F40-A284 HydrophobicContact CG-CB 4.44Å; F40-A284 HydrophobicContact CZ-CB 3.52Å; F40-A284 PolarHBondContact N-O 3.14Å; F40-A284 VanDerWaalsContact N-O 3.08Å; F40-A284 PolarHBondContact O-N 3.07Å; A284-W379 HydrophobicContact CB-CE3 4.11Å; A284-W379 HydrophobicContact CB-CZ3 4.29Å; A284-I381 HydrophobicContact CB-CD1 3.71Å
285V96.3Very high91.1Very high0 Ų035 Ų350%018%0.181CC..EExtended strand (participates in β ladder)trans-124.9154.3179-57.10000111A39 L283 I317 D319 F325 W379 L380 F382A39-V285 HydrophobicContact CB-CG1 4.27Å; L283-V285 HydrophobicContact CD1-CG1 4.17Å; L283-V285 HydrophobicContact CD2-CG1 3.79Å; L283-V285 HydrophobicContact CG-CG1 3.74Å; V285-I317 HydrophobicContact CB-CB 4.35Å; V285-I317 HydrophobicContact CB-CD1 4.04Å; V285-I317 HydrophobicContact CG1-CD1 4.17Å; V285-I317 HydrophobicContact CG2-CB 4.1Å; V285-I317 HydrophobicContact CG2-CD1 3.62Å; V285-I317 HydrophobicContact CG2-CG2 3.99Å; V285-D319 HydrophobicContact CG1-CB 3.91Å; V285-F325 HydrophobicContact CG1-CE2 4.4Å; V285-W379 VanDerWaalsContact C-CE3 3.49Å; V285-W379 WeakPolarHBondContact O-CA 3.37Å; V285-W379 VanDerWaalsContact O-CE3 3.3Å; V285-L380 HydrophobicContact CG2-CB 3.87Å; V285-L380 PolarHBondContact N-O 3.09Å; V285-L380 PolarHBondContact O-N 3.19Å; V285-F382 HydrophobicContact CG2-CD2 3.99Å; V285-F382 HydrophobicContact CG2-CE2 3.55Å
286N96.8Very high88.9Confident7 Ų741 Ų414%0.03721%0.213CC..EExtended strand (participates in β ladder)trans-109.4139.1-178.8-164.8-108.9000111.3K37 I288 I317 N318 G377 D378 W379K37-N286 HydrophobicContact CB-CB 4.28Å; N286-I288 PolarHBondContact O-N 3.4Å; N286-I317 VanDerWaalsContact O-CA 3.25Å; N286-I317 WeakPolarHBondContact O-CA 3.34Å; N286-N318 PolarHBondContact N-OD1 3.32Å; N286-N318 PolarHBondContact O-N 3.27Å; N286-N318 PolarHBondContact O-OD1 3.08Å; N286-G377 VanDerWaalsContact ND2-C 3.25Å; N286-G377 PolarHBondContact ND2-O 3.32Å; N286-G377 WeakPolarHBondContact OD1-CA 3.39Å; N286-D378 PolarHBondContact ND2-O 2.88Å; N286-W379 HydrophobicContact CB-CD2 4.31Å; N286-W379 HydrophobicContact CB-CE3 4.16Å; N286-W379 HydrophobicContact CB-CH2 4.29Å; N286-W379 HydrophobicContact CB-CZ2 4.43Å; N286-W379 HydrophobicContact CB-CZ3 4.15Å; N286-W379 PolarHBondContact ND2-NE1 2.8Å
287I96.6Very high86.6Confident0 Ų048.7 Ų48.70%025%0.247CC..EExtended strand (participates in β ladder)trans-74.3117171.7-62.2179000109Y315 Y316 I317 L374 G377 D378 L380I287-Y315 HydrophobicContact CD1-CD1 4.01Å; I287-Y315 HydrophobicContact CD1-CG 4.2Å; I287-Y315 HydrophobicContact CG2-CD1 4.06Å; I287-Y316 CarbonylContact C-O 3.28Å; I287-I317 HydrophobicContact CG1-CG2 4.14Å; I287-L374 HydrophobicContact CD1-CB 3.64Å; I287-L374 HydrophobicContact CD1-CD1 3.56Å; I287-L374 HydrophobicContact CD1-CG 4.23Å; I287-G377 PolarHBondContact O-N 2.69Å; I287-D378 HydrophobicContact CD1-CB 4.28Å; I287-D378 PolarHBondContact N-O 3.18Å; I287-L380 HydrophobicContact CD1-CD1 4.35Å; I287-L380 HydrophobicContact CD1-CG 4.42Å; I287-L380 HydrophobicContact CG1-CD1 4.34Å; I287-L380 HydrophobicContact CG1-CG 4.48Å
288I95.9Very high84.3Confident77 Ų7754.8 Ų54.840%0.39528%0.279SS..EExtended strand (participates in β ladder)trans-101.3-23.5-178.857.5169.5000113.2N286 Y316 N318 P357N286-I288 PolarHBondContact O-N 3.4Å; I288-Y316 VanDerWaalsContact CG1-O 3.24Å; I288-Y316 WeakPolarHBondContact CG1-O 3.38Å; I288-Y316 PolarHBondContact N-O 3.3Å; I288-N318 HydrophobicContact CG2-CB 3.77Å; I288-P357 HydrophobicContact CD1-CB 3.97Å
289A95.8Very high82Confident39 Ų3958.2 Ų58.232%0.32229%0.294SS..EExtended strand (participates in β ladder)trans-149.6155.7172.700000111.7Y316A289-Y316 HydrophobicContact CB-CD2 3.97Å; A289-Y316 HydrophobicContact CB-CG 4.31Å; A289-Y316 PolarHBondContact N-O 2.87Å; A289-Y316 PolarHBondContact O-N 2.9Å
290K95.9Very high79.5Confident54 Ų5461.7 Ų61.724%0.23532%0.316CS..EExtended strand (participates in β ladder)trans-134.1137.2176.6176.6-174.8-176.8175.50108.9F313 T314 Y315 E373 L374 V376K290-F313 VanDerWaalsContact CE-CE1 3.43Å; K290-T314 CarbonylContact C-O 3.57Å; K290-T314 WeakPolarHBondContact CA-O 3.39Å; K290-Y315 HydrophobicContact CB-CD1 4.05Å; K290-Y315 HydrophobicContact CB-CE1 4.25Å; K290-Y315 HydrophobicContact CD-CD1 4.39Å; K290-Y315 HydrophobicContact CD-CE1 3.75Å; K290-Y315 HydrophobicContact CG-CD1 3.89Å; K290-Y315 HydrophobicContact CG-CE1 3.66Å; K290-E373 VanDerWaalsContact NZ-CD 3.33Å; K290-E373 IonicContact NZ-OE1 2.66Å; K290-E373 PolarHBondContact NZ-OE1 3.31Å; K290-L374 WeakPolarHBondContact CD-O 3.42Å; K290-L374 WeakPolarHBondContact CE-O 3.37Å; K290-L374 PolarHBondContact NZ-O 2.88Å; K290-V376 HydrophobicContact CB-CG2 4.33Å
291K92.6Very high76.9Confident115 Ų11568.1 Ų68.150%0.536%0.361SS..EExtended strand (participates in β ladder)trans-122.3137.6167-64.6178.3-176.1165.90108.8T314 Y316K291-T314 PolarHBondContact N-O 2.79Å; K291-T314 PolarHBondContact O-N 3.03Å; K291-Y316 HydrophobicContact CD-CE2 3.82Å; K291-Y316 HydrophobicContact CG-CE2 4.08Å; K291-Y316 PolarHBondContact NZ-OH 2.92Å
292T90.5Very high74.6Confident81 Ų8171.9 Ų71.950%0.49740%0.4SS..EExtended strand (participates in β ladder)trans-103.9122.5170.4-51.10000107.2P311 F313T292-P311 HydrophobicContact CG2-CB 4.02Å; T292-F313 HydrophobicContact CG2-CD1 4.1Å; T292-F313 HydrophobicContact CG2-CE1 3.73Å; T292-F313 WeakPolarHBondContact OG1-CE1 3.23Å
293V77.5Confident72.1Confident44 Ų4476.5 Ų76.527%0.26743%0.428SS..EExtended strand (participates in β ladder)trans-102113.2173.6-174.40000107.6Y295 L298 V312V293-Y295 PolarHBondContact O-N 2.8Å; V293-L298 HydrophobicContact CG1-CD1 3.7Å; V293-L298 HydrophobicContact CG1-CG 4.05Å; V293-V312 PolarHBondContact N-O 3.12Å; V293-V312 PolarHBondContact O-N 2.91Å
294E64.1Low69.6Low125 Ų12584.9 Ų84.958%0.58447%0.467SS*.  trans-70.1123.6166.8-68.5172.1162.500108D296 K297E294-D296 PolarHBondContact O-N 3.17Å; E294-K297 PolarHBondContact O-N 2.77Å; E294-K297 IonicContact OE2-NZ 3.41Å; E294-K297 PolarHBondContact OE2-NZ 2.9Å
295Y53.2Low67.2Low124 Ų12492.8 Ų92.849%0.48650%0.503SS..G310 helixtrans-53.8-28-173.8-124.8-83.8000113.4V293 K297 L298 V312V293-Y295 PolarHBondContact O-N 2.8Å; Y295-K297 PolarHBondContact O-N 3.11Å; Y295-L298 PolarHBondContact O-N 3Å; Y295-V312 HydrophobicContact CD2-CG2 3.66Å; Y295-V312 HydrophobicContact CE2-CG2 3.36Å
296D49.8Very low64.9Low127 Ų12798.4 Ų98.468%0.67954%0.538SS*.G310 helixtrans-62.1-12.7-177.4-95.5-16.2000115.6E294E294-D296 PolarHBondContact O-N 3.17Å
297K48.5Very low62.6Low162 Ų162109.1 Ų109.170%0.70458%0.578SS**G310 helixtrans-103.8-2.5-176-70.7175.4-175.5149.40115.3E294 Y295E294-K297 PolarHBondContact O-N 2.77Å; E294-K297 IonicContact OE2-NZ 3.41Å; E294-K297 PolarHBondContact OE2-NZ 2.9Å; Y295-K297 PolarHBondContact O-N 3.11Å
298L49Very low60.4Low128 Ų128114.3 Ų114.367%0.6761%0.606SS**SBendtrans-101.8-7.1-176.2-70.6173.7000114.6V293 Y295V293-L298 HydrophobicContact CG1-CD1 3.7Å; V293-L298 HydrophobicContact CG1-CG 4.05Å; Y295-L298 PolarHBondContact O-N 3Å
299L43.2Very low58.9Low99 Ų99118.3 Ų118.352%0.51863%0.628SS.*SBendtrans-96.3133.4179.4-70.4168.5000111.5S301L299-S301 PolarHBondContact O-N 3.36Å
300P43Very low57.9Low105 Ų105121.4 Ų121.468%0.68264%0.636SS**  trans-55.8133.2162.5-17.929.1000109.3G302P300-G302 PolarHBondContact O-N 3.16Å
301S40.3Very low57.3Low136 Ų136120.9 Ų120.995%0.95164%0.638SS**THydrogen-bonded Turntrans-49.4110.1-177.4-48.80000111.9L299L299-S301 PolarHBondContact O-N 3.36Å
302G48Very low57.1Low80 Ų80117.1 Ų117.183%0.82562%0.624SS**THydrogen-bonded Turntrans13111.2167.400000118.8P300P300-G302 PolarHBondContact O-N 3.16Å
303V44.6Very low57.3Low101 Ų101113.4 Ų113.461%0.61260%0.601SS**  trans-99.1127173.5-1700000110.3
304E42.8Very low58.1Low177 Ų177112.1 Ų112.183%0.82759%0.593SS**  trans-57134.9-177.9-73.9-177.215500113.2T306E304-T306 PolarHBondContact O-N 3.06Å
305Q46Very low59.6Low167 Ų167106.1 Ų106.178%0.7857%0.566SS**  trans-64.995.1179.9-74.6159.2-1200111.4
306T49Very low61.7Low118 Ų118102.1 Ų102.172%0.72455%0.55SS*.  trans-14082.716652.40000110.9E304E304-T306 PolarHBondContact O-N 3.06Å
307R48.3Very low63.8Low233 Ų23396 Ų9688%0.87952%0.517SS*.SBendtrans158.7118.7143.8-86.5162.9-177.1-158.40.2111.7
308N51.3Low66Low108 Ų10889.9 Ų89.958%0.57849%0.492SS*.  trans40.8111.8169.2-71.515.1000120.2E310N308-E310 HydrophobicContact CB-CB 4.43Å; N308-E310 HydrophobicContact CB-CG 4.33Å; N308-E310 PolarHBondContact ND2-OE2 3.26Å; N308-E310 PolarHBondContact O-N 3.31Å
309D63.6Low68.1Low161 Ų16183.8 Ų83.886%0.86146%0.46SS*.  trans-69.420.3166.4-63.8-35.4000113.9
310E74.5Confident70.4Confident104 Ų10479.1 Ų79.149%0.48644%0.436SS..PPolyproline II helixtrans-79.8137.3-175.9-70.9174.6155.100110.7N308N308-E310 HydrophobicContact CB-CB 4.43Å; N308-E310 HydrophobicContact CB-CG 4.33Å; N308-E310 PolarHBondContact ND2-OE2 3.26Å; N308-E310 PolarHBondContact O-N 3.31Å
311P83.3Confident72.6Confident44 Ų4474.2 Ų74.229%0.28640%0.404SS..PPolyproline II helixtrans-64.8140.9-179.526.8-33.9000111.3T292 F313 F350T292-P311 HydrophobicContact CG2-CB 4.02Å; P311-F313 HydrophobicContact CB-CE1 4.39Å; P311-F313 HydrophobicContact CB-CE2 4.42Å; P311-F313 HydrophobicContact CB-CZ 4.04Å; P311-F313 HydrophobicContact CG-CE2 4.17Å; P311-F313 HydrophobicContact CG-CZ 3.96Å; P311-F350 HydrophobicContact CG-CD1 3.72Å; P311-F350 HydrophobicContact CG-CE1 3.65Å
312V89Confident74.9Confident35 Ų3570.8 Ų70.821%0.21237%0.371CS..EExtended strand (participates in β ladder)trans-101.8133170.6179.20000108.9V293 Y295 A351V293-V312 PolarHBondContact N-O 3.12Å; V293-V312 PolarHBondContact O-N 2.91Å; Y295-V312 HydrophobicContact CD2-CG2 3.66Å; Y295-V312 HydrophobicContact CE2-CG2 3.36Å; V312-A351 WeakPolarHBondContact CA-O 3.48Å; V312-A351 WeakPolarHBondContact CG1-O 3.22Å; V312-A351 HydrophobicContact CG2-CB 4.4Å
313F93.7Very high76.9Confident3 Ų367.5 Ų67.51%0.01334%0.337CS..EExtended strand (participates in β ladder)trans-107.9140-179.7-61.9-65.9000112.4K290 T292 P311 Y315 F350 A351 S352 S353 E373K290-F313 VanDerWaalsContact CE-CE1 3.43Å; T292-F313 HydrophobicContact CG2-CD1 4.1Å; T292-F313 HydrophobicContact CG2-CE1 3.73Å; T292-F313 WeakPolarHBondContact OG1-CE1 3.23Å; P311-F313 HydrophobicContact CB-CE1 4.39Å; P311-F313 HydrophobicContact CB-CE2 4.42Å; P311-F313 HydrophobicContact CB-CZ 4.04Å; P311-F313 HydrophobicContact CG-CE2 4.17Å; P311-F313 HydrophobicContact CG-CZ 3.96Å; F313-Y315 HydrophobicContact CB-CD2 4.38Å; F313-Y315 HydrophobicContact CB-CE1 4.31Å; F313-Y315 HydrophobicContact CB-CE2 3.64Å; F313-Y315 HydrophobicContact CG-CE2 4.48Å; F313-F350 HydrophobicContact CD2-CB 3.68Å; F313-F350 HydrophobicContact CD2-CD2 4.27Å; F313-F350 HydrophobicContact CD2-CG 4Å; F313-F350 HydrophobicContact CE2-CB 3.79Å; F313-F350 HydrophobicContact CE2-CD1 4.05Å; F313-F350 AromaticContact CE2-CD2 3.67Å; F313-F350 HydrophobicContact CE2-CD2 3.67Å; F313-F350 HydrophobicContact CE2-CE2 4.22Å; F313-F350 AromaticContact CE2-CG 3.56Å; F313-F350 HydrophobicContact CE2-CG 3.56Å; F313-A351 PolarHBondContact N-O 2.93Å; F313-A351 VanDerWaalsContact N-O 3.1Å; F313-S352 CarbonylContact O-C 3.56Å; F313-S352 WeakPolarHBondContact O-CA 3.42Å; F313-S353 PolarHBondContact O-N 3.41Å; F313-E373 HydrophobicContact CE1-CG 4.28Å; F313-E373 HydrophobicContact CE2-CB 4.09Å; F313-E373 HydrophobicContact CE2-CG 3.92Å; F313-E373 HydrophobicContact CZ-CB 4.29Å; F313-E373 HydrophobicContact CZ-CG 3.69Å
314T94.7Very high79.1Confident17 Ų1762.8 Ų62.810%0.10431%0.309CS..EExtended strand (participates in β ladder)trans-117.1117.8168.4-58.70000108.1K290 K291 Y316 S353 W355K290-T314 CarbonylContact C-O 3.57Å; K290-T314 WeakPolarHBondContact CA-O 3.39Å; K291-T314 PolarHBondContact N-O 2.79Å; K291-T314 PolarHBondContact O-N 3.03Å; T314-Y316 HydrophobicContact CG2-CD2 4.48Å; T314-Y316 HydrophobicContact CG2-CE2 3.82Å; T314-S353 PolarHBondContact OG1-OG 2.68Å; T314-W355 HydrophobicContact CG2-CG 4.24Å
315Y96.3Very high81.4Confident0 Ų054.3 Ų54.30%027%0.269CS..EExtended strand (participates in β ladder)trans-106134.9176.4-55.6-74.7000110.2I287 K290 F313 S353 L354 W355 L371 L374I287-Y315 HydrophobicContact CD1-CD1 4.01Å; I287-Y315 HydrophobicContact CD1-CG 4.2Å; I287-Y315 HydrophobicContact CG2-CD1 4.06Å; K290-Y315 HydrophobicContact CB-CD1 4.05Å; K290-Y315 HydrophobicContact CB-CE1 4.25Å; K290-Y315 HydrophobicContact CD-CD1 4.39Å; K290-Y315 HydrophobicContact CD-CE1 3.75Å; K290-Y315 HydrophobicContact CG-CD1 3.89Å; K290-Y315 HydrophobicContact CG-CE1 3.66Å; F313-Y315 HydrophobicContact CB-CD2 4.38Å; F313-Y315 HydrophobicContact CB-CE1 4.31Å; F313-Y315 HydrophobicContact CB-CE2 3.64Å; F313-Y315 HydrophobicContact CG-CE2 4.48Å; Y315-S353 PolarHBondContact N-O 3.38Å; Y315-L354 HydrophobicContact CD2-CD2 4Å; Y315-L354 HydrophobicContact CG-CD2 4.34Å; Y315-L354 WeakPolarHBondContact O-CA 3.45Å; Y315-W355 PolarHBondContact O-N 3.44Å; Y315-L371 HydrophobicContact CD2-CD1 4.36Å; Y315-L371 HydrophobicContact CE2-CD1 4.34Å; Y315-L374 HydrophobicContact CD1-CB 4.42Å; Y315-L374 HydrophobicContact CE1-CB 3.74Å; Y315-L374 HydrophobicContact CE2-CD1 4.46Å; Y315-L374 PolarHBondContact OH-N 2.92Å
316Y95.9Very high83.3Confident39 Ų3948.3 Ų48.315%0.15325%0.248CC..EExtended strand (participates in β ladder)trans-104.6129171.3-62.2-95.9000108.2I287 I288 A289 K291 T314 W355I287-Y316 CarbonylContact C-O 3.28Å; I288-Y316 VanDerWaalsContact CG1-O 3.24Å; I288-Y316 WeakPolarHBondContact CG1-O 3.38Å; I288-Y316 PolarHBondContact N-O 3.3Å; A289-Y316 HydrophobicContact CB-CD2 3.97Å; A289-Y316 HydrophobicContact CB-CG 4.31Å; A289-Y316 PolarHBondContact N-O 2.87Å; A289-Y316 PolarHBondContact O-N 2.9Å; K291-Y316 HydrophobicContact CD-CE2 3.82Å; K291-Y316 HydrophobicContact CG-CE2 4.08Å; K291-Y316 PolarHBondContact NZ-OH 2.92Å; T314-Y316 HydrophobicContact CG2-CD2 4.48Å; T314-Y316 HydrophobicContact CG2-CE2 3.82Å; Y316-W355 CarbonylContact C-O 3.6Å; Y316-W355 WeakPolarHBondContact CA-O 3.34Å; Y316-W355 HydrophobicContact CD1-CB 3.63Å; Y316-W355 HydrophobicContact CD1-CG 4.48Å; Y316-W355 HydrophobicContact CE1-CB 3.77Å; Y316-W355 HydrophobicContact CE1-CG 4.18Å; Y316-W355 HydrophobicContact CG-CB 4.34Å
317I95.4Very high84.9Confident0 Ų043.1 Ų43.10%022%0.216CC..EExtended strand (participates in β ladder)trans-108.7164.3178.455.8155.9000111.3V285 N286 I287 D319 F325 W355 P357 I365 L380V285-I317 HydrophobicContact CB-CB 4.35Å; V285-I317 HydrophobicContact CB-CD1 4.04Å; V285-I317 HydrophobicContact CG1-CD1 4.17Å; V285-I317 HydrophobicContact CG2-CB 4.1Å; V285-I317 HydrophobicContact CG2-CD1 3.62Å; V285-I317 HydrophobicContact CG2-CG2 3.99Å; N286-I317 VanDerWaalsContact O-CA 3.25Å; N286-I317 WeakPolarHBondContact O-CA 3.34Å; I287-I317 HydrophobicContact CG1-CG2 4.14Å; I317-D319 VanDerWaalsContact CD1-O 3.25Å; I317-D319 WeakPolarHBondContact CD1-O 3.19Å; I317-D319 WeakPolarHBondContact CG1-O 3.27Å; I317-D319 PolarHBondContact O-N 3.19Å; I317-F325 HydrophobicContact CD1-CE2 3.97Å; I317-F325 HydrophobicContact CD1-CZ 4.33Å; I317-W355 VanDerWaalsContact CG1-O 3.3Å; I317-W355 WeakPolarHBondContact CG1-O 3.43Å; I317-W355 PolarHBondContact N-O 2.89Å; I317-P357 WeakPolarHBondContact O-CD 3.44Å; I317-I365 HydrophobicContact CD1-CD1 3.47Å; I317-I365 VanDerWaalsContact CD1-CD1 3.47Å; I317-I365 HydrophobicContact CG1-CD1 3.8Å; I317-L380 HydrophobicContact CG2-CD1 4.2Å
318N93.3Very high86.6Confident32 Ų3235.7 Ų35.717%0.17119%0.19CC..SBendtrans-81.310.7-17763.1-11.1000115.2K37 A39 N286 I288K37-N318 PolarHBondContact O-ND2 2.85Å; A39-N318 PolarHBondContact N-ND2 3.04Å; A39-N318 VanDerWaalsContact N-ND2 3.14Å; N286-N318 PolarHBondContact N-OD1 3.32Å; N286-N318 PolarHBondContact O-N 3.27Å; N286-N318 PolarHBondContact O-OD1 3.08Å; I288-N318 HydrophobicContact CG2-CB 3.77Å
319D93.1Very high87.9Confident0 Ų036 Ų360%019%0.192CC..  trans-143.1155.2175-164.1-17000108.7A39 V285 I317 S324 F325 G356 I365 Y399 P402A39-D319 HydrophobicContact CB-CB 4.34Å; V285-D319 HydrophobicContact CG1-CB 3.91Å; I317-D319 VanDerWaalsContact CD1-O 3.25Å; I317-D319 WeakPolarHBondContact CD1-O 3.19Å; I317-D319 WeakPolarHBondContact CG1-O 3.27Å; I317-D319 PolarHBondContact O-N 3.19Å; D319-S324 PolarHBondContact OD1-N 2.99Å; D319-S324 WeakPolarHBondContact OD2-CB 3.3Å; D319-S324 PolarHBondContact OD2-OG 3.26Å; D319-F325 HydrophobicContact CB-CE2 4.24Å; D319-G356 WeakPolarHBondContact O-CA 3.26Å; D319-I365 WeakPolarHBondContact O-CD1 3.33Å; D319-Y399 HydrophobicContact CB-CE2 4.42Å; D319-Y399 WeakPolarHBondContact OD1-CE2 3.21Å; D319-Y399 PolarHBondContact OD1-OH 3.38Å; D319-Y399 PolarHBondContact OD2-OH 3.19Å; D319-P402 WeakPolarHBondContact OD2-CG 3.33Å
320G91.4Very high87.9Confident2 Ų232.2 Ų32.22%0.02118%0.178CC..  trans-159.3-168.1-169.600000114.8Y322 G323 S324 F325 D363G320-Y322 PolarHBondContact O-N 2.91Å; G320-G323 CarbonylContact O-C 3.09Å; G320-G323 WeakPolarHBondContact O-CA 3.41Å; G320-G323 PolarHBondContact O-N 2.92Å; G320-S324 PolarHBondContact O-N 3.34Å; G320-F325 WeakPolarHBondContact O-CB 3.23Å; G320-F325 PolarHBondContact O-N 3.4Å; G320-D363 WeakPolarHBondContact CA-OD1 3.32Å
321V90.4Very high87.6Confident1 Ų132.5 Ų32.51%0.00618%0.179CC..THydrogen-bonded Turntrans-63.6-29.5-177.21780000111.6G323 A326 K328 L329 D363 I365V321-G323 PolarHBondContact O-N 2.9Å; V321-A326 WeakPolarHBondContact O-CA 3.33Å; V321-A326 WeakPolarHBondContact O-CB 3.3Å; V321-A326 PolarHBondContact O-N 3.01Å; V321-K328 HydrophobicContact CG2-CB 4.49Å; V321-L329 HydrophobicContact CG1-CD1 3.68Å; V321-L329 HydrophobicContact CG1-CD2 3.66Å; V321-L329 HydrophobicContact CG1-CG 3.39Å; V321-D363 PolarHBondContact N-OD1 3.36Å; V321-I365 HydrophobicContact CG2-CG1 4.24Å
322Y88.7Confident86.6Confident64 Ų6437.7 Ų37.725%0.25120%0.197SC..THydrogen-bonded Turntrans-821.8174.6-57.7-77000114.2G320 D360 D363 S394 F396G320-Y322 PolarHBondContact O-N 2.91Å; Y322-D360 HydrophobicContact CE2-CB 3.9Å; Y322-D360 PolarHBondContact OH-OD1 3.45Å; Y322-D360 PolarHBondContact OH-OD2 3.29Å; Y322-D360 VanDerWaalsContact OH-OD2 3.13Å; Y322-D363 HydrophobicContact CD2-CB 4.4Å; Y322-D363 HydrophobicContact CE2-CB 4.03Å; Y322-S394 PolarHBondContact O-OG 3.45Å; Y322-S394 VanDerWaalsContact O-OG 3.06Å; Y322-F396 AromaticContact CD1-CD1 3.75Å; Y322-F396 HydrophobicContact CD1-CD1 3.75Å; Y322-F396 AromaticContact CD1-CE1 3.88Å; Y322-F396 HydrophobicContact CD1-CE1 3.88Å; Y322-F396 HydrophobicContact CD1-CG 4.26Å; Y322-F396 AromaticContact CD2-CD1 3.65Å; Y322-F396 HydrophobicContact CD2-CD1 3.65Å; Y322-F396 AromaticContact CD2-CE1 3.4Å; Y322-F396 HydrophobicContact CD2-CE1 3.4Å; Y322-F396 VanDerWaalsContact CD2-CE1 3.4Å; Y322-F396 HydrophobicContact CD2-CZ 4.44Å; Y322-F396 HydrophobicContact CE1-CD1 4.22Å; Y322-F396 AromaticContact CE1-CE1 3.91Å; Y322-F396 HydrophobicContact CE1-CE1 3.91Å; Y322-F396 HydrophobicContact CE1-CZ 4.17Å; Y322-F396 HydrophobicContact CE2-CD1 4.14Å; Y322-F396 AromaticContact CE2-CE1 3.43Å; Y322-F396 HydrophobicContact CE2-CE1 3.43Å; Y322-F396 VanDerWaalsContact CE2-CE1 3.43Å; Y322-F396 HydrophobicContact CE2-CZ 4.11Å; Y322-F396 AromaticContact CG-CD1 3.42Å; Y322-F396 HydrophobicContact CG-CD1 3.42Å; Y322-F396 VanDerWaalsContact CG-CD1 3.42Å; Y322-F396 AromaticContact CG-CE1 3.62Å; Y322-F396 HydrophobicContact CG-CE1 3.62Å; Y322-F396 HydrophobicContact CG-CG 4.29Å; Y322-F396 AromaticContact CZ-CE1 3.69Å; Y322-F396 AromaticContact CZ-CZ 3.95Å
323G89.3Confident85.4Confident11 Ų1137.6 Ų37.611%0.11320%0.195CC..THydrogen-bonded Turntrans-126.8-119.3178.500000110.8G320 V321 F325 A326 Y399G320-G323 CarbonylContact O-C 3.09Å; G320-G323 WeakPolarHBondContact O-CA 3.41Å; G320-G323 PolarHBondContact O-N 2.92Å; V321-G323 PolarHBondContact O-N 2.9Å; G323-F325 VanDerWaalsContact C-N 3.25Å; G323-F325 PolarHBondContact O-N 3.32Å; G323-A326 PolarHBondContact O-N 3.2Å; G323-Y399 VanDerWaalsContact CA-CZ 3.47Å
324S91.3Very high84Confident2 Ų244.6 Ų44.61%0.01423%0.233CC..THydrogen-bonded Turntrans-71.4-17-172.8-59.70000114.8Y41 D319 G320 M385 T389 Y399Y41-S324 WeakPolarHBondContact OH-CB 3.42Å; Y41-S324 PolarHBondContact OH-OG 2.98Å; D319-S324 PolarHBondContact OD1-N 2.99Å; D319-S324 WeakPolarHBondContact OD2-CB 3.3Å; D319-S324 PolarHBondContact OD2-OG 3.26Å; G320-S324 PolarHBondContact O-N 3.34Å; S324-M385 WeakPolarHBondContact O-CE 3.49Å; S324-T389 WeakPolarHBondContact CA-O 3.32Å; S324-T389 VanDerWaalsContact O-CA 3.3Å; S324-T389 WeakPolarHBondContact O-CA 3.35Å; S324-T389 WeakPolarHBondContact O-CB 3.29Å; S324-T389 VanDerWaalsContact O-CG2 3.22Å; S324-T389 WeakPolarHBondContact O-CG2 3.26Å; S324-Y399 PolarHBondContact N-OH 2.9Å; S324-Y399 PolarHBondContact OG-OH 2.82Å
325F91Very high83Confident0 Ų044.6 Ų44.60%023%0.233CC..THydrogen-bonded Turntrans-100.719.6-179.3-60-89.1000113L283 V285 I317 D319 G320 G323 S327 K328 L333 I365 F382 M385L283-F325 HydrophobicContact CD2-CE2 3.72Å; L283-F325 HydrophobicContact CD2-CZ 3.69Å; V285-F325 HydrophobicContact CG1-CE2 4.4Å; I317-F325 HydrophobicContact CD1-CE2 3.97Å; I317-F325 HydrophobicContact CD1-CZ 4.33Å; D319-F325 HydrophobicContact CB-CE2 4.24Å; G320-F325 WeakPolarHBondContact O-CB 3.23Å; G320-F325 PolarHBondContact O-N 3.4Å; G323-F325 VanDerWaalsContact C-N 3.25Å; G323-F325 PolarHBondContact O-N 3.32Å; F325-S327 PolarHBondContact O-N 3.16Å; F325-S327 VanDerWaalsContact O-N 3.15Å; F325-K328 WeakPolarHBondContact O-CB 3.24Å; F325-K328 PolarHBondContact O-N 3Å; F325-L333 HydrophobicContact CD1-CD2 4.25Å; F325-I365 HydrophobicContact CB-CG1 4.45Å; F325-I365 HydrophobicContact CB-CG2 4.21Å; F325-I365 HydrophobicContact CD1-CG2 3.41Å; F325-I365 VanDerWaalsContact CD1-CG2 3.41Å; F325-I365 HydrophobicContact CD2-CD1 3.87Å; F325-I365 HydrophobicContact CD2-CG1 4.45Å; F325-I365 HydrophobicContact CD2-CG2 4.34Å; F325-I365 HydrophobicContact CE1-CG2 3.73Å; F325-I365 HydrophobicContact CE2-CD1 4.09Å; F325-I365 HydrophobicContact CG-CD1 4.22Å; F325-I365 HydrophobicContact CG-CG1 4.34Å; F325-I365 HydrophobicContact CG-CG2 3.73Å; F325-I365 HydrophobicContact CZ-CG2 4.32Å; F325-F382 AromaticContact CE1-CD1 3.92Å; F325-F382 HydrophobicContact CE1-CD1 3.92Å; F325-F382 HydrophobicContact CE1-CD2 4.41Å; F325-F382 HydrophobicContact CE1-CE1 4Å; F325-F382 HydrophobicContact CE1-CG 4.09Å; F325-F382 HydrophobicContact CE1-CZ 4.28Å; F325-F382 HydrophobicContact CZ-CD1 4.22Å; F325-F382 AromaticContact CZ-CD2 3.88Å; F325-F382 HydrophobicContact CZ-CD2 3.88Å; F325-F382 HydrophobicContact CZ-CE1 4.24Å; F325-F382 AromaticContact CZ-CE2 3.94Å; F325-F382 HydrophobicContact CZ-CE2 3.94Å; F325-F382 HydrophobicContact CZ-CG 4Å; F325-F382 HydrophobicContact CZ-CZ 4.08Å; F325-M385 HydrophobicContact CD1-CE 3.65Å; F325-M385 HydrophobicContact CE1-CE 3.49Å; F325-M385 VanDerWaalsContact CE1-CE 3.49Å; F325-M385 HydrophobicContact CE1-SD 4.25Å; F325-M385 HydrophobicContact CE2-CE 4.44Å; F325-M385 HydrophobicContact CG-CE 4.22Å; F325-M385 HydrophobicContact CZ-CE 3.93Å
326A86.9Confident82.4Confident41 Ų4149.6 Ų49.634%0.33926%0.264SS..THydrogen-bonded Turntrans-56.2-30.4178.300000113.8V321 G323 K328 L329V321-A326 WeakPolarHBondContact O-CA 3.33Å; V321-A326 WeakPolarHBondContact O-CB 3.3Å; V321-A326 PolarHBondContact O-N 3.01Å; G323-A326 PolarHBondContact O-N 3.2Å; A326-K328 PolarHBondContact O-N 3.26Å; A326-K328 VanDerWaalsContact O-N 3.1Å; A326-L329 WeakPolarHBondContact O-CB 3.12Å; A326-L329 PolarHBondContact O-N 3.45Å
327S81.6Confident82.2Confident8 Ų848.4 Ų48.46%0.05626%0.261CS..Hα-helixtrans-58.4-21.2174.455.80000113.4F325 L329 S330 E331 L333F325-S327 PolarHBondContact O-N 3.16Å; F325-S327 VanDerWaalsContact O-N 3.15Å; S327-L329 PolarHBondContact O-N 3.21Å; S327-S330 PolarHBondContact O-N 3Å; S327-S330 PolarHBondContact O-OG 2.8Å; S327-E331 PolarHBondContact O-N 2.9Å; S327-L333 WeakPolarHBondContact OG-CD2 3.45Å
328K83.4Confident82.1Confident77 Ų7753.7 Ų53.734%0.33529%0.285SS..Hα-helixtrans-62.8-28.1174.6-172.859.3174.8-176.80113.4V321 F325 A326 L333 I365V321-K328 HydrophobicContact CG2-CB 4.49Å; F325-K328 WeakPolarHBondContact O-CB 3.24Å; F325-K328 PolarHBondContact O-N 3Å; A326-K328 PolarHBondContact O-N 3.26Å; A326-K328 VanDerWaalsContact O-N 3.1Å; K328-L333 HydrophobicContact CD-CB 4.15Å; K328-I365 WeakPolarHBondContact CE-O 3.43Å
329L78.4Confident82.1Confident116 Ų11653.4 Ų53.461%0.60728%0.284SS*.Hα-helixtrans-74.8-28.4177.9-65.9174000112.7V321 A326 S327V321-L329 HydrophobicContact CG1-CD1 3.68Å; V321-L329 HydrophobicContact CG1-CD2 3.66Å; V321-L329 HydrophobicContact CG1-CG 3.39Å; A326-L329 WeakPolarHBondContact O-CB 3.12Å; A326-L329 PolarHBondContact O-N 3.45Å; S327-L329 PolarHBondContact O-N 3.21Å
330S65.3Low82Confident81 Ų8156 Ų5657%0.56630%0.297SS*.Hα-helixtrans-104.5-27.9-174.555.40000113.5S327S327-S330 PolarHBondContact O-N 3Å; S327-S330 PolarHBondContact O-OG 2.8Å
331E66.6Low81.8Confident109 Ų10961.1 Ų61.151%0.50932%0.318SS..SBendtrans-134.3151.3-172-62.4-179.5-173.400110.6S327 L333S327-E331 PolarHBondContact O-N 2.9Å; E331-L333 PolarHBondContact O-N 3.34Å
332K63Low81.2Confident154 Ų15471.2 Ų71.267%0.6736%0.362SS*.  trans-69.879.6165.6-77.3176.6179.6161.50108.4D163 N334D163-K332 IonicContact OD1-NZ 3.14Å; D163-K332 PolarHBondContact OD1-NZ 3.45Å; D163-K332 IonicContact OD2-NZ 3.6Å; D163-K332 PolarHBondContact OD2-NZ 3.22Å; K332-N334 PolarHBondContact O-N 2.62Å; K332-N334 VanDerWaalsContact O-N 3.11Å
333L64.1Low80.5Confident32 Ų3273.6 Ų73.617%0.16837%0.371CS..  trans-68108.4173.6-166.972.5000108.1F325 S327 K328 E331 T335F325-L333 HydrophobicContact CD1-CD2 4.25Å; S327-L333 WeakPolarHBondContact OG-CD2 3.45Å; K328-L333 HydrophobicContact CD-CB 4.15Å; E331-L333 PolarHBondContact O-N 3.34Å; L333-T335 VanDerWaalsContact C-N 3.25Å; L333-T335 HydrophobicContact CD1-CG2 3.87Å; L333-T335 HydrophobicContact CD2-CG2 3.57Å; L333-T335 WeakPolarHBondContact CD2-OG1 3.07Å; L333-T335 HydrophobicContact CG-CG2 3.51Å; L333-T335 PolarHBondContact O-N 3.01Å
334N65Low79.8Confident150 Ų15080.8 Ų80.880%0.80240%0.399SS*.  trans-91.961.1170.5-71.4-16.7000108.8K332K332-N334 PolarHBondContact O-N 2.62Å; K332-N334 VanDerWaalsContact O-N 3.11Å
335T72.2Confident78.8Confident17 Ų1789.9 Ų89.910%0.10444%0.442CS..  trans-84.1115171.441.20000109.2L333 M385L333-T335 VanDerWaalsContact C-N 3.25Å; L333-T335 HydrophobicContact CD1-CG2 3.87Å; L333-T335 HydrophobicContact CD2-CG2 3.57Å; L333-T335 WeakPolarHBondContact CD2-OG1 3.07Å; L333-T335 HydrophobicContact CG-CG2 3.51Å; L333-T335 PolarHBondContact O-N 3.01Å; T335-M385 HydrophobicContact CG2-SD 3.62Å
336T84.9Confident78.2Confident106 Ų10697.3 Ų97.365%0.6548%0.482SS*.  trans-89.1123.1175.1-54.20000108.8
337P91.9Very high78.1Confident14 Ų1499 Ų999%0.09148%0.483CS..  trans-70.7132.9173.528.7-33.3000110.2L354 L371 L380 F382P337-L354 HydrophobicContact CB-CD1 3.76Å; P337-L354 HydrophobicContact CG-CD1 3.77Å; P337-L371 HydrophobicContact CG-CD2 4.34Å; P337-L380 HydrophobicContact CB-CD1 4.47Å; P337-F382 HydrophobicContact CB-CD1 4.5Å; P337-F382 HydrophobicContact CB-CE1 3.72Å; P337-F382 HydrophobicContact CB-CE2 4.39Å; P337-F382 HydrophobicContact CB-CZ 3.68Å
338E93.1Very high78.4Confident111 Ų111102.6 Ų102.652%0.51951%0.506SS..EExtended strand (participates in β ladder)trans-106.1134.1169.4-64.2-169.6176.900110.2L380 I381E338-L380 CarbonylContact O-C 3.54Å; E338-L380 WeakPolarHBondContact O-CA 3.49Å; E338-I381 HydrophobicContact CB-CB 4.37Å; E338-I381 PolarHBondContact N-O 3.21Å; E338-I381 PolarHBondContact O-N 3.47Å
339V92.9Very high78.7Confident25 Ų25102.9 Ų102.915%0.15251%0.51CS..EExtended strand (participates in β ladder)trans-81.3121.9177.9-178.80000108.7K341 Y343 L371 P372 L374 L380V339-K341 HydrophobicContact CG1-CB 4.32Å; V339-K341 PolarHBondContact O-N 3.18Å; V339-Y343 HydrophobicContact CB-CD1 4.38Å; V339-Y343 HydrophobicContact CB-CE1 4.11Å; V339-Y343 HydrophobicContact CG1-CD1 4.42Å; V339-L371 HydrophobicContact CG2-CD2 3.79Å; V339-P372 HydrophobicContact CG2-CG 4.21Å; V339-L374 HydrophobicContact CG1-CD2 3.73Å; V339-L374 HydrophobicContact CG2-CD1 4.23Å; V339-L374 HydrophobicContact CG2-CD2 4.13Å; V339-L380 HydrophobicContact CG2-CD2 3.94Å
340H91.6Very high79.4Confident55 Ų5598.5 Ų98.526%0.25549%0.486SS..SBendtrans-63.8-40.5179.4166-81.3000112.6D26 I29 K342 W379 I381D26-H340 IonicContact OD1-CD2 3.45Å; D26-H340 PolarHBondContact OD1-CD2 3.13Å; D26-H340 IonicContact OD1-NE2 3.43Å; D26-H340 PolarHBondContact OD1-NE2 3.18Å; I29-H340 HydrophobicContact CD1-CB 4.21Å; I29-H340 WeakPolarHBondContact CD1-CD2 3.12Å; H340-K342 PolarHBondContact O-N 2.76Å; H340-W379 HydrophobicContact CB-CB 4.01Å; H340-W379 PolarHBondContact N-O 2.9Å; H340-I381 HydrophobicContact CB-CD1 4.31Å; H340-I381 HydrophobicContact CB-CG1 4.09Å
341K85.4Confident80.7Confident110 Ų11096.9 Ų96.948%0.47848%0.478SS..SBendtrans-66.9134.9-179.8-72.5-174.1-177.7172.30110.3V339 Y343 D378V339-K341 HydrophobicContact CG1-CB 4.32Å; V339-K341 PolarHBondContact O-N 3.18Å; K341-Y343 WeakPolarHBondContact O-CD1 3.48Å; K341-Y343 PolarHBondContact O-N 3.13Å; K341-D378 WeakPolarHBondContact CE-OD1 3.42Å; K341-D378 VanDerWaalsContact NZ-CG 3.29Å; K341-D378 IonicContact NZ-OD1 2.64Å; K341-D378 PolarHBondContact NZ-OD1 2.89Å; K341-D378 IonicContact NZ-OD2 2.57Å; K341-D378 PolarHBondContact NZ-OD2 3.39Å
342K78.3Confident82Confident212 Ų21291.8 Ų91.892%0.92245%0.454SS*.  trans-68.9111.1169.1-64.2-175.4-179.3177.70109.3H340H340-K342 PolarHBondContact O-N 2.76Å
343Y74.9Confident83.4Confident115 Ų11585 Ų8545%0.45143%0.427SS..  trans-96.6156.8170.153.8-85.9000110.1V339 K341 E347 P372V339-Y343 HydrophobicContact CB-CD1 4.38Å; V339-Y343 HydrophobicContact CB-CE1 4.11Å; V339-Y343 HydrophobicContact CG1-CD1 4.42Å; K341-Y343 WeakPolarHBondContact O-CD1 3.48Å; K341-Y343 PolarHBondContact O-N 3.13Å; Y343-E347 VanDerWaalsContact CB-OE2 3.29Å; Y343-E347 WeakPolarHBondContact CB-OE2 3.34Å; Y343-E347 HydrophobicContact CD2-CB 4.5Å; Y343-P372 HydrophobicContact CD1-CG 4.17Å; Y343-P372 HydrophobicContact CE1-CG 4.45Å; Y343-P372 HydrophobicContact CG-CG 4.28Å
344K74.6Confident84.8Confident161 Ų16183.5 Ų83.570%0.742%0.419SS*.  trans-70.2143.6174-64176.5-178.4173.50109.2D346 E347K344-D346 PolarHBondContact O-N 3.38Å; K344-E347 HydrophobicContact CB-CG 4.26Å; K344-E347 PolarHBondContact N-OE1 3.41Å; K344-E347 WeakPolarHBondContact O-CB 3.46Å; K344-E347 PolarHBondContact O-N 2.89Å
345E70.6Confident86.3Confident194 Ų19478.9 Ų78.991%0.90739%0.39SS*.THydrogen-bonded Turntrans-55-25.3179-72.1-175.4165.500113.2
346D78.5Confident87.3Confident156 Ų15678.1 Ų78.183%0.83439%0.385SS*.THydrogen-bonded Turntrans-90.85.9-179.6-55.5-40.4000114.3K344K344-D346 PolarHBondContact O-N 3.38Å
347E83.1Confident87.6Confident77 Ų7775.6 Ų75.636%0.3637%0.371SS..PPolyproline II helixtrans-69136178-83.4177.8-140.300111.8Y343 K344 L349Y343-E347 VanDerWaalsContact CB-OE2 3.29Å; Y343-E347 WeakPolarHBondContact CB-OE2 3.34Å; Y343-E347 HydrophobicContact CD2-CB 4.5Å; K344-E347 HydrophobicContact CB-CG 4.26Å; K344-E347 PolarHBondContact N-OE1 3.41Å; K344-E347 WeakPolarHBondContact O-CB 3.46Å; K344-E347 PolarHBondContact O-N 2.89Å; E347-L349 PolarHBondContact O-N 2.76Å
348P88.2Confident87.4Confident83 Ų8375.7 Ų75.754%0.53937%0.372SS..PPolyproline II helixtrans-65.8135.2-178.727.1-33.5000110.8F350P348-F350 HydrophobicContact CB-CE2 3.96Å; P348-F350 HydrophobicContact CB-CZ 3.83Å; P348-F350 HydrophobicContact CG-CE2 3.82Å; P348-F350 HydrophobicContact CG-CZ 3.8Å; P348-F350 WeakPolarHBondContact O-CD2 3.24Å; P348-F350 WeakPolarHBondContact O-CE2 3.25Å
349L91Very high86.6Confident82 Ų8275.9 Ų75.943%0.42938%0.384SS..EExtended strand (participates in β ladder)trans-97.9138.9174.4-60.4178.9000110.2E347 L370 P372E347-L349 PolarHBondContact O-N 2.76Å; L349-L370 HydrophobicContact CB-CB 4.29Å; L349-L370 HydrophobicContact CD1-CB 4.37Å; L349-P372 HydrophobicContact CD2-CB 4.4Å
350F91.8Very high86.4Confident24 Ų2477.2 Ų77.211%0.10539%0.39CS..EExtended strand (participates in β ladder)trans-122.1145.3-177.1-58.3-85000111P311 F313 P348 S352 L371 E373P311-F350 HydrophobicContact CG-CD1 3.72Å; P311-F350 HydrophobicContact CG-CE1 3.65Å; F313-F350 HydrophobicContact CD2-CB 3.68Å; F313-F350 HydrophobicContact CD2-CD2 4.27Å; F313-F350 HydrophobicContact CD2-CG 4Å; F313-F350 HydrophobicContact CE2-CB 3.79Å; F313-F350 HydrophobicContact CE2-CD1 4.05Å; F313-F350 AromaticContact CE2-CD2 3.67Å; F313-F350 HydrophobicContact CE2-CD2 3.67Å; F313-F350 HydrophobicContact CE2-CE2 4.22Å; F313-F350 AromaticContact CE2-CG 3.56Å; F313-F350 HydrophobicContact CE2-CG 3.56Å; P348-F350 HydrophobicContact CB-CE2 3.96Å; P348-F350 HydrophobicContact CB-CZ 3.83Å; P348-F350 HydrophobicContact CG-CE2 3.82Å; P348-F350 HydrophobicContact CG-CZ 3.8Å; P348-F350 WeakPolarHBondContact O-CD2 3.24Å; P348-F350 WeakPolarHBondContact O-CE2 3.25Å; F350-S352 PolarHBondContact O-N 3.5Å; F350-S352 PolarHBondContact O-OG 2.68Å; F350-L371 PolarHBondContact N-O 2.73Å; F350-L371 PolarHBondContact O-N 2.86Å; F350-E373 HydrophobicContact CD2-CB 4.25Å; F350-E373 HydrophobicContact CE2-CB 4Å
351A92.9Very high86.2Confident47 Ų4782.4 Ų82.439%0.38842%0.415SS..EExtended strand (participates in β ladder)trans-59.5123.7169.600000109.5V312 F313V312-A351 WeakPolarHBondContact CA-O 3.48Å; V312-A351 WeakPolarHBondContact CG1-O 3.22Å; V312-A351 HydrophobicContact CG2-CB 4.4Å; F313-A351 PolarHBondContact N-O 2.93Å; F313-A351 VanDerWaalsContact N-O 3.1Å
352S93.3Very high86.4Confident2 Ų282 Ų821%0.01442%0.418CS..EExtended strand (participates in β ladder)trans-137.6149.5-171.3-61.10000111.9F313 F350 N368 C369F313-S352 CarbonylContact O-C 3.56Å; F313-S352 WeakPolarHBondContact O-CA 3.42Å; F350-S352 PolarHBondContact O-N 3.5Å; F350-S352 PolarHBondContact O-OG 2.68Å; S352-N368 CarbonylContact O-C 3.55Å; S352-N368 WeakPolarHBondContact O-CA 3.48Å; S352-C369 PolarHBondContact N-O 2.85Å; S352-C369 PolarHBondContact O-N 3.31Å; S352-C369 PolarHBondContact O-SG 3.46Å
353S93.4Very high87Confident13 Ų1372 Ų729%0.09137%0.374CS..EExtended strand (participates in β ladder)trans-122.8144.817254.90000110.8F313 T314 Y315 W355 V366 E367F313-S353 PolarHBondContact O-N 3.41Å; T314-S353 PolarHBondContact OG1-OG 2.68Å; Y315-S353 PolarHBondContact N-O 3.38Å; S353-W355 PolarHBondContact OG-NE1 3.3Å; S353-V366 WeakPolarHBondContact CA-O 3.41Å; S353-E367 VanDerWaalsContact CB-O 3.29Å; S353-E367 WeakPolarHBondContact CB-O 3.3Å
354L94.3Very high87.8Confident0 Ų069.3 Ų69.30%037%0.366CS..EExtended strand (participates in β ladder)trans-114.8130.7177.9-58.3-175.7000111Y315 P337 I365 V366 L371 L380 F382Y315-L354 HydrophobicContact CD2-CD2 4Å; Y315-L354 HydrophobicContact CG-CD2 4.34Å; Y315-L354 WeakPolarHBondContact O-CA 3.45Å; P337-L354 HydrophobicContact CB-CD1 3.76Å; P337-L354 HydrophobicContact CG-CD1 3.77Å; L354-I365 PolarHBondContact O-N 2.82Å; L354-V366 HydrophobicContact CB-CB 3.95Å; L354-V366 HydrophobicContact CB-CG2 4.24Å; L354-V366 HydrophobicContact CD1-CB 4.26Å; L354-V366 HydrophobicContact CD1-CG2 3.97Å; L354-V366 HydrophobicContact CG-CB 4.12Å; L354-V366 HydrophobicContact CG-CG2 4.36Å; L354-V366 PolarHBondContact N-O 3.33Å; L354-V366 PolarHBondContact O-N 3.35Å; L354-L371 HydrophobicContact CD2-CD1 4.15Å; L354-L380 HydrophobicContact CD1-CD1 3.82Å; L354-L380 HydrophobicContact CD2-CD1 3.85Å; L354-F382 HydrophobicContact CD1-CZ 3.81Å
355W94.5Very high88.6Confident52 Ų5261.8 Ų61.820%0.19733%0.333CS..EExtended strand (participates in β ladder)trans-127.6148.4-177.2-66.573.5000110.6T314 Y315 Y316 I317 S353 E361 D363 Q364T314-W355 HydrophobicContact CG2-CG 4.24Å; Y315-W355 PolarHBondContact O-N 3.44Å; Y316-W355 CarbonylContact C-O 3.6Å; Y316-W355 WeakPolarHBondContact CA-O 3.34Å; Y316-W355 HydrophobicContact CD1-CB 3.63Å; Y316-W355 HydrophobicContact CD1-CG 4.48Å; Y316-W355 HydrophobicContact CE1-CB 3.77Å; Y316-W355 HydrophobicContact CE1-CG 4.18Å; Y316-W355 HydrophobicContact CG-CB 4.34Å; I317-W355 VanDerWaalsContact CG1-O 3.3Å; I317-W355 WeakPolarHBondContact CG1-O 3.43Å; I317-W355 PolarHBondContact N-O 2.89Å; S353-W355 PolarHBondContact OG-NE1 3.3Å; W355-E361 WeakPolarHBondContact CZ3-O 3.33Å; W355-D363 CarbonylContact C-O 3.4Å; W355-D363 WeakPolarHBondContact CA-O 3.22Å; W355-Q364 HydrophobicContact CD2-CB 4.09Å; W355-Q364 HydrophobicContact CD2-CG 4.07Å; W355-Q364 HydrophobicContact CE3-CB 3.87Å; W355-Q364 HydrophobicContact CE3-CG 4.35Å; W355-Q364 HydrophobicContact CH2-CB 3.87Å; W355-Q364 HydrophobicContact CH2-CG 4.09Å; W355-Q364 HydrophobicContact CZ2-CB 4.09Å; W355-Q364 HydrophobicContact CZ2-CG 3.79Å; W355-Q364 HydrophobicContact CZ3-CB 3.76Å; W355-Q364 HydrophobicContact CZ3-CG 4.36Å
356G93.6Very high89.5Confident1 Ų153.3 Ų53.31%0.0130%0.295CS..  trans-77.1178.917100000113D319 S358 D363D319-G356 WeakPolarHBondContact O-CA 3.26Å; G356-S358 VanDerWaalsContact C-N 3.32Å; G356-S358 PolarHBondContact O-N 2.92Å; G356-D363 VanDerWaalsContact CA-CG 3.42Å; G356-D363 WeakPolarHBondContact CA-OD2 3.34Å; G356-D363 PolarHBondContact N-O 3.37Å
357P92.1Very high90Very high53 Ų5352 Ų5234%0.34428%0.283SS..THydrogen-bonded Turntrans-80.3-9.3-169.931.3-35.5000114.1I288 I317 C359I288-P357 HydrophobicContact CD1-CB 3.97Å; I317-P357 WeakPolarHBondContact O-CD 3.44Å; P357-C359 VanDerWaalsContact C-N 3.33Å; P357-C359 PolarHBondContact O-N 2.91Å
358S87.4Confident90.2Very high17 Ų1754 Ų5412%0.11930%0.297CS..THydrogen-bonded Turntrans-78.7-12.5-164.669.50000115.6G356 D360 D363 N397G356-S358 VanDerWaalsContact C-N 3.32Å; G356-S358 PolarHBondContact O-N 2.92Å; S358-D360 PolarHBondContact O-N 3.5Å; S358-D360 WeakPolarHBondContact OG-CB 3.48Å; S358-D360 PolarHBondContact OG-N 3.26Å; S358-D363 WeakPolarHBondContact CB-OD2 3.29Å; S358-D363 PolarHBondContact N-OD2 3.35Å; S358-D363 WeakPolarHBondContact OG-CB 3.35Å; S358-D363 PolarHBondContact OG-OD2 3.44Å; S358-N397 VanDerWaalsContact CA-ND2 3.32Å; S358-N397 WeakPolarHBondContact CA-ND2 3.47Å; S358-N397 WeakPolarHBondContact CB-ND2 3.3Å; S358-N397 PolarHBondContact O-ND2 2.85Å
359C76.6Confident90.4Very high114 Ų11451.1 Ų51.177%0.7728%0.278SS*.  trans58.316.2-170.2-55.50000114.7P357P357-C359 VanDerWaalsContact C-N 3.33Å; P357-C359 PolarHBondContact O-N 2.91Å
360D87.6Confident90.4Very high53 Ų5352.9 Ų52.928%0.28329%0.287SS..  trans-81.1146.8170.7-164.6-60.9000110.4Y322 S358 L362 D363Y322-D360 HydrophobicContact CE2-CB 3.9Å; Y322-D360 PolarHBondContact OH-OD1 3.45Å; Y322-D360 PolarHBondContact OH-OD2 3.29Å; Y322-D360 VanDerWaalsContact OH-OD2 3.13Å; S358-D360 PolarHBondContact O-N 3.5Å; S358-D360 WeakPolarHBondContact OG-CB 3.48Å; S358-D360 PolarHBondContact OG-N 3.26Å; D360-L362 PolarHBondContact O-N 3.05Å; D360-L362 WeakPolarHBondContact OD1-CB 3.31Å; D360-L362 PolarHBondContact OD1-N 2.9Å; D360-D363 HydrophobicContact CB-CB 4.26Å; D360-D363 WeakPolarHBondContact O-CB 3.38Å; D360-D363 PolarHBondContact O-N 2.93Å; D360-D363 VanDerWaalsContact O-N 3.15Å
361E87.5Confident90.4Very high164 Ų16452 Ų5277%0.76628%0.284SS*.THydrogen-bonded Turntrans-65.8-24.7177.363.4-176.1179.900113W355 D363W355-E361 WeakPolarHBondContact CZ3-O 3.33Å; E361-D363 VanDerWaalsContact C-N 3.34Å
362L89.5Confident90.4Very high103 Ų10350 Ų5054%0.53927%0.267SS..THydrogen-bonded Turntrans-83.8-9.6176-59.4-179.4000113.1D360 Q364D360-L362 PolarHBondContact O-N 3.05Å; D360-L362 WeakPolarHBondContact OD1-CB 3.31Å; D360-L362 PolarHBondContact OD1-N 2.9Å; L362-Q364 PolarHBondContact O-N 3.27Å
363D91.3Very high90.4Very high2 Ų255.2 Ų55.21%0.01129%0.291CS..  trans-83.934179.5-156.214.7000112.7G320 V321 Y322 W355 G356 S358 D360 E361G320-D363 WeakPolarHBondContact CA-OD1 3.32Å; V321-D363 PolarHBondContact N-OD1 3.36Å; Y322-D363 HydrophobicContact CD2-CB 4.4Å; Y322-D363 HydrophobicContact CE2-CB 4.03Å; W355-D363 CarbonylContact C-O 3.4Å; W355-D363 WeakPolarHBondContact CA-O 3.22Å; G356-D363 VanDerWaalsContact CA-CG 3.42Å; G356-D363 WeakPolarHBondContact CA-OD2 3.34Å; G356-D363 PolarHBondContact N-O 3.37Å; S358-D363 WeakPolarHBondContact CB-OD2 3.29Å; S358-D363 PolarHBondContact N-OD2 3.35Å; S358-D363 WeakPolarHBondContact OG-CB 3.35Å; S358-D363 PolarHBondContact OG-OD2 3.44Å; D360-D363 HydrophobicContact CB-CB 4.26Å; D360-D363 WeakPolarHBondContact O-CB 3.38Å; D360-D363 PolarHBondContact O-N 2.93Å; D360-D363 VanDerWaalsContact O-N 3.15Å; E361-D363 VanDerWaalsContact C-N 3.34Å
364Q91.2Very high90.5Very high58 Ų5855 Ų5527%0.27129%0.288SS..EExtended strand (participates in β ladder)trans-91.9119.4173.5-167.5178.635.500109.4W355 L362W355-Q364 HydrophobicContact CD2-CB 4.09Å; W355-Q364 HydrophobicContact CD2-CG 4.07Å; W355-Q364 HydrophobicContact CE3-CB 3.87Å; W355-Q364 HydrophobicContact CE3-CG 4.35Å; W355-Q364 HydrophobicContact CH2-CB 3.87Å; W355-Q364 HydrophobicContact CH2-CG 4.09Å; W355-Q364 HydrophobicContact CZ2-CB 4.09Å; W355-Q364 HydrophobicContact CZ2-CG 3.79Å; W355-Q364 HydrophobicContact CZ3-CB 3.76Å; W355-Q364 HydrophobicContact CZ3-CG 4.36Å; L362-Q364 PolarHBondContact O-N 3.27Å
365I91.5Very high90.5Very high2 Ų258.1 Ų58.11%0.0131%0.31CS..EExtended strand (participates in β ladder)trans-93.6-51.6-174.2-54.4169.3000109.6I317 D319 V321 F325 K328 L354I317-I365 HydrophobicContact CD1-CD1 3.47Å; I317-I365 VanDerWaalsContact CD1-CD1 3.47Å; I317-I365 HydrophobicContact CG1-CD1 3.8Å; D319-I365 WeakPolarHBondContact O-CD1 3.33Å; V321-I365 HydrophobicContact CG2-CG1 4.24Å; F325-I365 HydrophobicContact CB-CG1 4.45Å; F325-I365 HydrophobicContact CB-CG2 4.21Å; F325-I365 HydrophobicContact CD1-CG2 3.41Å; F325-I365 VanDerWaalsContact CD1-CG2 3.41Å; F325-I365 HydrophobicContact CD2-CD1 3.87Å; F325-I365 HydrophobicContact CD2-CG1 4.45Å; F325-I365 HydrophobicContact CD2-CG2 4.34Å; F325-I365 HydrophobicContact CE1-CG2 3.73Å; F325-I365 HydrophobicContact CE2-CD1 4.09Å; F325-I365 HydrophobicContact CG-CD1 4.22Å; F325-I365 HydrophobicContact CG-CG1 4.34Å; F325-I365 HydrophobicContact CG-CG2 3.73Å; F325-I365 HydrophobicContact CZ-CG2 4.32Å; K328-I365 WeakPolarHBondContact CE-O 3.43Å; L354-I365 PolarHBondContact O-N 2.82Å
366V90.8Very high90.6Very high17 Ų1759.9 Ų59.910%0.10333%0.327CS..EExtended strand (participates in β ladder)trans-125.6114.4178.2-175.80000108.3S353 L354 C369S353-V366 WeakPolarHBondContact CA-O 3.41Å; L354-V366 HydrophobicContact CB-CB 3.95Å; L354-V366 HydrophobicContact CB-CG2 4.24Å; L354-V366 HydrophobicContact CD1-CB 4.26Å; L354-V366 HydrophobicContact CD1-CG2 3.97Å; L354-V366 HydrophobicContact CG-CB 4.12Å; L354-V366 HydrophobicContact CG-CG2 4.36Å; L354-V366 PolarHBondContact N-O 3.33Å; L354-V366 PolarHBondContact O-N 3.35Å; V366-C369 HydrophobicContact CG1-CB 3.76Å
367E89Confident90.7Very high127 Ų12760.3 Ų60.359%0.59333%0.331SS*.EExtended strand (participates in β ladder)trans-68.8-48.9-178.4-167.3-173.4169.100111.3S353S353-E367 VanDerWaalsContact CB-O 3.29Å; S353-E367 WeakPolarHBondContact CB-O 3.3Å
368N87.4Confident90.9Very high120 Ų12058.5 Ų58.564%0.64232%0.319SS*.EExtended strand (participates in β ladder)trans-141.5125.6-178.4-63.8-66.8000110.4S352S352-N368 CarbonylContact O-C 3.55Å; S352-N368 WeakPolarHBondContact O-CA 3.48Å
369C91.3Very high91.4Very high23 Ų2358.2 Ų58.216%0.15532%0.315CS..EExtended strand (participates in β ladder)trans-145.8164.8170.959.60000110.6S352 V366S352-C369 PolarHBondContact N-O 2.85Å; S352-C369 PolarHBondContact O-N 3.31Å; S352-C369 PolarHBondContact O-SG 3.46Å; V366-C369 HydrophobicContact CG1-CB 3.76Å
370L91.7Very high92.3Very high118 Ų11852.8 Ų52.862%0.61828%0.278SS*.EExtended strand (participates in β ladder)trans-104.5119.5173.6-68.3175.3000108.4L349L349-L370 HydrophobicContact CB-CB 4.29Å; L349-L370 HydrophobicContact CD1-CB 4.37Å
371L91.9Very high92.8Very high6 Ų650.9 Ų50.93%0.03127%0.268CS..EExtended strand (participates in β ladder)trans-134.2149.4179.1-67.5173.4000109.5Y315 P337 V339 F350 L354 L374Y315-L371 HydrophobicContact CD2-CD1 4.36Å; Y315-L371 HydrophobicContact CE2-CD1 4.34Å; P337-L371 HydrophobicContact CG-CD2 4.34Å; V339-L371 HydrophobicContact CG2-CD2 3.79Å; F350-L371 PolarHBondContact N-O 2.73Å; F350-L371 PolarHBondContact O-N 2.86Å; L354-L371 HydrophobicContact CD2-CD1 4.15Å; L371-L374 HydrophobicContact CD1-CD1 4.18Å
372P93.1Very high93.2Very high5 Ų543.1 Ų43.13%0.03223%0.232CC..EExtended strand (participates in β ladder)trans-60.6167.8163.929.4-34.6000110V339 Y343 L349 L374V339-P372 HydrophobicContact CG2-CG 4.21Å; Y343-P372 HydrophobicContact CD1-CG 4.17Å; Y343-P372 HydrophobicContact CE1-CG 4.45Å; Y343-P372 HydrophobicContact CG-CG 4.28Å; L349-P372 HydrophobicContact CD2-CB 4.4Å; P372-L374 HydrophobicContact CG-CD2 4.08Å; P372-L374 WeakPolarHBondContact O-CG 3.3Å; P372-L374 PolarHBondContact O-N 3.46Å; P372-L374 VanDerWaalsContact O-N 3.13Å
373E93.5Very high93.4Very high112 Ų11241.3 Ų41.352%0.52322%0.222SC..  trans-67.8114.4174.2-174.6174.1-175.900110.5K290 F313 F350K290-E373 VanDerWaalsContact NZ-CD 3.33Å; K290-E373 IonicContact NZ-OE1 2.66Å; K290-E373 PolarHBondContact NZ-OE1 3.31Å; F313-E373 HydrophobicContact CE1-CG 4.28Å; F313-E373 HydrophobicContact CE2-CB 4.09Å; F313-E373 HydrophobicContact CE2-CG 3.92Å; F313-E373 HydrophobicContact CZ-CB 4.29Å; F313-E373 HydrophobicContact CZ-CG 3.69Å; F350-E373 HydrophobicContact CD2-CB 4.25Å; F350-E373 HydrophobicContact CE2-CB 4Å
374L94.6Very high93.5Very high7 Ų745.5 Ų45.54%0.03725%0.245CC..  trans-100162-179.7-56.1175.9000111.5I287 K290 Y315 V339 L371 P372 L380I287-L374 HydrophobicContact CD1-CB 3.64Å; I287-L374 HydrophobicContact CD1-CD1 3.56Å; I287-L374 HydrophobicContact CD1-CG 4.23Å; K290-L374 WeakPolarHBondContact CD-O 3.42Å; K290-L374 WeakPolarHBondContact CE-O 3.37Å; K290-L374 PolarHBondContact NZ-O 2.88Å; Y315-L374 HydrophobicContact CD1-CB 4.42Å; Y315-L374 HydrophobicContact CE1-CB 3.74Å; Y315-L374 HydrophobicContact CE2-CD1 4.46Å; Y315-L374 PolarHBondContact OH-N 2.92Å; V339-L374 HydrophobicContact CG1-CD2 3.73Å; V339-L374 HydrophobicContact CG2-CD1 4.23Å; V339-L374 HydrophobicContact CG2-CD2 4.13Å; L371-L374 HydrophobicContact CD1-CD1 4.18Å; P372-L374 HydrophobicContact CG-CD2 4.08Å; P372-L374 WeakPolarHBondContact O-CG 3.3Å; P372-L374 PolarHBondContact O-N 3.46Å; P372-L374 VanDerWaalsContact O-N 3.13Å; L374-L380 HydrophobicContact CD1-CD2 3.76Å
375S95.4Very high93.6Very high66 Ų6642.8 Ų42.846%0.46223%0.232SC..  trans-116.7157.7177.6-67.60000112.4G377 D378S375-G377 PolarHBondContact O-N 3.33Å; S375-D378 PolarHBondContact N-OD2 3.07Å; S375-D378 VanDerWaalsContact O-CB 3.27Å; S375-D378 WeakPolarHBondContact O-CB 3.44Å; S375-D378 VanDerWaalsContact O-CG 3.26Å; S375-D378 PolarHBondContact O-N 2.79Å; S375-D378 VanDerWaalsContact O-N 3.09Å
376V96.6Very high93.6Very high90 Ų9042.7 Ų42.755%0.54523%0.232SC..THydrogen-bonded Turntrans-59.3130.8169.91760000109.1K290K290-V376 HydrophobicContact CB-CG2 4.33Å
377G94.9Very high93.6Very high9 Ų943.2 Ų43.29%0.09324%0.236CC..THydrogen-bonded Turntrans96.9-5.8-174.900000114.7K37 N286 I287 S375K37-G377 VanDerWaalsContact NZ-CA 3.34Å; K37-G377 PolarHBondContact NZ-O 3.5Å; N286-G377 VanDerWaalsContact ND2-C 3.25Å; N286-G377 PolarHBondContact ND2-O 3.32Å; N286-G377 WeakPolarHBondContact OD1-CA 3.39Å; I287-G377 PolarHBondContact O-N 2.69Å; S375-G377 PolarHBondContact O-N 3.33Å
378D96.2Very high93.4Very high16 Ų1638.9 Ų38.99%0.08623%0.225CC..  trans-76.8155.3173.7-65.9-9.5000111.5N286 I287 K341 S375N286-D378 PolarHBondContact ND2-O 2.88Å; I287-D378 HydrophobicContact CD1-CB 4.28Å; I287-D378 PolarHBondContact N-O 3.18Å; K341-D378 WeakPolarHBondContact CE-OD1 3.42Å; K341-D378 VanDerWaalsContact NZ-CG 3.29Å; K341-D378 IonicContact NZ-OD1 2.64Å; K341-D378 PolarHBondContact NZ-OD1 2.89Å; K341-D378 IonicContact NZ-OD2 2.57Å; K341-D378 PolarHBondContact NZ-OD2 3.39Å; S375-D378 PolarHBondContact N-OD2 3.07Å; S375-D378 VanDerWaalsContact O-CB 3.27Å; S375-D378 WeakPolarHBondContact O-CB 3.44Å; S375-D378 VanDerWaalsContact O-CG 3.26Å; S375-D378 PolarHBondContact O-N 2.79Å; S375-D378 VanDerWaalsContact O-N 3.09Å
379W97.2Very high93.1Very high10 Ų1033.4 Ų33.44%0.03820%0.196CC..EExtended strand (participates in β ladder)trans-108.3138.1-175.5-67.689.8000111.6I29 H32 T33 K37 R38 F40 A284 V285 N286 H340I29-W379 HydrophobicContact CD1-CB 3.81Å; I29-W379 HydrophobicContact CD1-CD2 4.13Å; I29-W379 HydrophobicContact CD1-CE3 4.44Å; I29-W379 HydrophobicContact CD1-CG 3.86Å; I29-W379 HydrophobicContact CG1-CB 4.43Å; I29-W379 HydrophobicContact CG1-CD2 3.78Å; I29-W379 HydrophobicContact CG1-CE3 4.1Å; I29-W379 HydrophobicContact CG1-CG 3.93Å; I29-W379 HydrophobicContact CG2-CD2 4.48Å; I29-W379 HydrophobicContact CG2-CG 4.15Å; H32-W379 HydrophobicContact CB-CH2 3.82Å; H32-W379 HydrophobicContact CB-CZ2 3.84Å; T33-W379 PolarHBondContact OG1-NE1 2.92Å; K37-W379 HydrophobicContact CB-CH2 4.4Å; K37-W379 HydrophobicContact CB-CZ2 4Å; K37-W379 HydrophobicContact CG-CZ2 4.15Å; R38-W379 WeakPolarHBondContact O-CH2 3.27Å; F40-W379 HydrophobicContact CD1-CH2 4.2Å; F40-W379 HydrophobicContact CD1-CZ3 4.04Å; F40-W379 HydrophobicContact CE1-CE3 4.42Å; F40-W379 AromaticContact CE1-CH2 3.99Å; F40-W379 HydrophobicContact CE1-CH2 3.99Å; F40-W379 AromaticContact CE1-CZ3 3.79Å; F40-W379 HydrophobicContact CE1-CZ3 3.79Å; A284-W379 HydrophobicContact CB-CE3 4.11Å; A284-W379 HydrophobicContact CB-CZ3 4.29Å; V285-W379 VanDerWaalsContact C-CE3 3.49Å; V285-W379 WeakPolarHBondContact O-CA 3.37Å; V285-W379 VanDerWaalsContact O-CE3 3.3Å; N286-W379 HydrophobicContact CB-CD2 4.31Å; N286-W379 HydrophobicContact CB-CE3 4.16Å; N286-W379 HydrophobicContact CB-CH2 4.29Å; N286-W379 HydrophobicContact CB-CZ2 4.43Å; N286-W379 HydrophobicContact CB-CZ3 4.15Å; N286-W379 PolarHBondContact ND2-NE1 2.8Å; H340-W379 HydrophobicContact CB-CB 4.01Å; H340-W379 PolarHBondContact N-O 2.9Å
380L96.9Very high92.4Very high0 Ų032.6 Ų32.60%019%0.19CC..EExtended strand (participates in β ladder)trans-114.7139.6170-64.3175.7000108.9V285 I287 I317 P337 E338 V339 L354 L374 F382V285-L380 HydrophobicContact CG2-CB 3.87Å; V285-L380 PolarHBondContact N-O 3.09Å; V285-L380 PolarHBondContact O-N 3.19Å; I287-L380 HydrophobicContact CD1-CD1 4.35Å; I287-L380 HydrophobicContact CD1-CG 4.42Å; I287-L380 HydrophobicContact CG1-CD1 4.34Å; I287-L380 HydrophobicContact CG1-CG 4.48Å; I317-L380 HydrophobicContact CG2-CD1 4.2Å; P337-L380 HydrophobicContact CB-CD1 4.47Å; E338-L380 CarbonylContact O-C 3.54Å; E338-L380 WeakPolarHBondContact O-CA 3.49Å; V339-L380 HydrophobicContact CG2-CD2 3.94Å; L354-L380 HydrophobicContact CD1-CD1 3.82Å; L354-L380 HydrophobicContact CD2-CD1 3.85Å; L374-L380 HydrophobicContact CD1-CD2 3.76Å; L380-F382 HydrophobicContact CB-CE2 3.92Å
381I96.8Very high91.2Very high14 Ų1429 Ų297%0.07218%0.183CC..EExtended strand (participates in β ladder)trans-110.4135.7-179.7-50.5-56.5000108.6I25 I29 T282 L283 A284 E338 H340I25-I381 HydrophobicContact CD1-CG2 4.49Å; I25-I381 HydrophobicContact CG2-CD1 3.71Å; I29-I381 HydrophobicContact CD1-CD1 3.89Å; T282-I381 HydrophobicContact CG2-CG2 3.29Å; L283-I381 CarbonylContact O-C 3.54Å; L283-I381 WeakPolarHBondContact O-CA 2.91Å; A284-I381 HydrophobicContact CB-CD1 3.71Å; E338-I381 HydrophobicContact CB-CB 4.37Å; E338-I381 PolarHBondContact N-O 3.21Å; E338-I381 PolarHBondContact O-N 3.47Å; H340-I381 HydrophobicContact CB-CD1 4.31Å; H340-I381 HydrophobicContact CB-CG1 4.09Å
382F95.7Very high89.7Confident1 Ų136.2 Ų36.20%0.00422%0.216CC..EExtended strand (participates in β ladder)trans-126.5109.5177.9-69.1-90.7000109.4T282 L283 V285 F325 P337 L354 L380 M385T282-F382 WeakPolarHBondContact CA-O 3.4Å; L283-F382 HydrophobicContact CB-CB 4.32Å; L283-F382 PolarHBondContact N-O 2.9Å; L283-F382 PolarHBondContact O-N 3.11Å; V285-F382 HydrophobicContact CG2-CD2 3.99Å; V285-F382 HydrophobicContact CG2-CE2 3.55Å; F325-F382 AromaticContact CE1-CD1 3.92Å; F325-F382 HydrophobicContact CE1-CD1 3.92Å; F325-F382 HydrophobicContact CE1-CD2 4.41Å; F325-F382 HydrophobicContact CE1-CE1 4Å; F325-F382 HydrophobicContact CE1-CG 4.09Å; F325-F382 HydrophobicContact CE1-CZ 4.28Å; F325-F382 HydrophobicContact CZ-CD1 4.22Å; F325-F382 AromaticContact CZ-CD2 3.88Å; F325-F382 HydrophobicContact CZ-CD2 3.88Å; F325-F382 HydrophobicContact CZ-CE1 4.24Å; F325-F382 AromaticContact CZ-CE2 3.94Å; F325-F382 HydrophobicContact CZ-CE2 3.94Å; F325-F382 HydrophobicContact CZ-CG 4Å; F325-F382 HydrophobicContact CZ-CZ 4.08Å; P337-F382 HydrophobicContact CB-CD1 4.5Å; P337-F382 HydrophobicContact CB-CE1 3.72Å; P337-F382 HydrophobicContact CB-CE2 4.39Å; P337-F382 HydrophobicContact CB-CZ 3.68Å; L354-F382 HydrophobicContact CD1-CZ 3.81Å; L380-F382 HydrophobicContact CB-CE2 3.92Å; F382-M385 HydrophobicContact CB-CG 3.65Å; F382-M385 HydrophobicContact CB-SD 4.38Å; F382-M385 VanDerWaalsContact O-CG 3.24Å; F382-M385 WeakPolarHBondContact O-CG 3.36Å
383D93.9Very high88.1Confident64 Ų6442.4 Ų42.434%0.34225%0.245SC..SBendtrans-78165173.4-80.5-21.2000112.4T282 M385T282-D383 WeakPolarHBondContact CG2-OD1 3.46Å; T282-D383 PolarHBondContact OG1-OD1 3.41Å; D383-M385 VanDerWaalsContact C-N 3.28Å; D383-M385 PolarHBondContact O-N 3.34Å
384N92.9Very high86.6Confident91 Ų9139 Ų3949%0.48723%0.233SC..SBendtrans6134178.3-53.7-60.8000113.8S278 S279 F281 G386S278-N384 CarbonylContact O-C 3.6Å; S278-N384 WeakPolarHBondContact O-CA 3.32Å; S278-N384 PolarHBondContact OG-O 3.29Å; S279-N384 VanDerWaalsContact CA-OD1 3.3Å; S279-N384 WeakPolarHBondContact CA-OD1 3.29Å; S279-N384 WeakPolarHBondContact CB-OD1 3.34Å; F281-N384 PolarHBondContact O-N 3.08Å; N384-G386 PolarHBondContact O-N 2.91Å
385M93.7Very high85Confident0 Ų045.6 Ų45.60%027%0.274CS..  trans-98.630-173.9-71.8-64.3-73.800112.8Y41 S278 F281 L283 S324 F325 T335 F382 D383 T389Y41-M385 HydrophobicContact CE1-CB 3.78Å; Y41-M385 VanDerWaalsContact CE1-O 3.23Å; Y41-M385 WeakPolarHBondContact CE1-O 3.49Å; S278-M385 PolarHBondContact O-N 2.94Å; F281-M385 PolarHBondContact O-N 3.29Å; L283-M385 HydrophobicContact CB-CB 3.92Å; L283-M385 HydrophobicContact CB-CG 3.98Å; L283-M385 HydrophobicContact CD2-CE 3.73Å; S324-M385 WeakPolarHBondContact O-CE 3.49Å; F325-M385 HydrophobicContact CD1-CE 3.65Å; F325-M385 HydrophobicContact CE1-CE 3.49Å; F325-M385 VanDerWaalsContact CE1-CE 3.49Å; F325-M385 HydrophobicContact CE1-SD 4.25Å; F325-M385 HydrophobicContact CE2-CE 4.44Å; F325-M385 HydrophobicContact CG-CE 4.22Å; F325-M385 HydrophobicContact CZ-CE 3.93Å; T335-M385 HydrophobicContact CG2-SD 3.62Å; F382-M385 HydrophobicContact CB-CG 3.65Å; F382-M385 HydrophobicContact CB-SD 4.38Å; F382-M385 VanDerWaalsContact O-CG 3.24Å; F382-M385 WeakPolarHBondContact O-CG 3.36Å; D383-M385 VanDerWaalsContact C-N 3.28Å; D383-M385 PolarHBondContact O-N 3.34Å; M385-T389 HydrophobicContact CB-CG2 4.34Å; M385-T389 HydrophobicContact CE-CG2 3.7Å; M385-T389 WeakPolarHBondContact O-CB 3.39Å; M385-T389 WeakPolarHBondContact O-CG2 3.31Å; M385-T389 PolarHBondContact O-OG1 3.32Å; M385-T389 HydrophobicContact SD-CG2 4.04Å
386G92.5Very high83.5Confident0 Ų046.2 Ų46.20%027%0.268CS..  trans-99.1-8.4-175.600000117N71 V277 S278 N384N71-G386 WeakPolarHBondContact CB-O 3.24Å; N71-G386 PolarHBondContact ND2-O 3.47Å; V277-G386 WeakPolarHBondContact CG2-O 3.4Å; V277-G386 WeakPolarHBondContact O-CA 3.42Å; S278-G386 PolarHBondContact O-N 2.92Å; S278-G386 VanDerWaalsContact O-N 3.09Å; N384-G386 PolarHBondContact O-N 2.91Å
387S90.4Very high81.5Confident28 Ų2846.7 Ų46.720%0.19627%0.268CS..SBendtrans-120.3124.6-178.3-176.80000111.8C70 C274 T389C70-S387 CarbonylContact O-C 3.51Å; C70-S387 WeakPolarHBondContact O-CA 3.33Å; C274-S387 WeakPolarHBondContact CB-OG 3.47Å; S387-T389 PolarHBondContact O-N 3.39Å
388G84.2Confident80.1Confident36 Ų3653.5 Ų53.537%0.37130%0.302SS..SBendtrans73.113176.700000114.3C70C70-G388 PolarHBondContact O-N 2.87Å
389T81.5Confident78.5Confident5 Ų554.3 Ų54.33%0.03130%0.304CS..  trans-109-36.3-175.357.20000111.7Y41 S324 M385 S387 G391Y41-T389 VanDerWaalsContact OH-CB 3.27Å; Y41-T389 WeakPolarHBondContact OH-CB 3.46Å; Y41-T389 PolarHBondContact OH-OG1 3.49Å; S324-T389 WeakPolarHBondContact CA-O 3.32Å; S324-T389 VanDerWaalsContact O-CA 3.3Å; S324-T389 WeakPolarHBondContact O-CA 3.35Å; S324-T389 WeakPolarHBondContact O-CB 3.29Å; S324-T389 VanDerWaalsContact O-CG2 3.22Å; S324-T389 WeakPolarHBondContact O-CG2 3.26Å; M385-T389 HydrophobicContact CB-CG2 4.34Å; M385-T389 HydrophobicContact CE-CG2 3.7Å; M385-T389 WeakPolarHBondContact O-CB 3.39Å; M385-T389 WeakPolarHBondContact O-CG2 3.31Å; M385-T389 PolarHBondContact O-OG1 3.32Å; M385-T389 HydrophobicContact SD-CG2 4.04Å; S387-T389 PolarHBondContact O-N 3.39Å; T389-G391 VanDerWaalsContact C-N 3.27Å; T389-G391 PolarHBondContact O-N 3.24Å
390L77.1Confident77.3Confident6 Ų659.4 Ų59.43%0.03133%0.328CS..SBendtrans-89.457-178.3-72161.2000111.4Y41 N71 T73 F281 R401 I404Y41-L390 HydrophobicContact CD2-CD2 3.62Å; Y41-L390 HydrophobicContact CD2-CG 4.44Å; Y41-L390 HydrophobicContact CE2-CD2 3.41Å; Y41-L390 VanDerWaalsContact CE2-CD2 3.41Å; Y41-L390 HydrophobicContact CE2-CG 4.03Å; Y41-L390 HydrophobicContact CG-CD2 4.41Å; N71-L390 VanDerWaalsContact ND2-CD1 3.31Å; N71-L390 WeakPolarHBondContact ND2-CD1 3.19Å; T73-L390 HydrophobicContact CG2-CB 4.34Å; T73-L390 HydrophobicContact CG2-CD1 3.99Å; F281-L390 HydrophobicContact CD1-CD1 4.13Å; F281-L390 HydrophobicContact CE1-CD1 4.11Å; L390-R401 VanDerWaalsContact C-NH2 3.35Å; L390-R401 PolarHBondContact O-NH2 3.08Å; L390-I404 HydrophobicContact CD1-CD1 4.23Å; L390-I404 HydrophobicContact CD2-CD1 3.74Å; L390-I404 HydrophobicContact CD2-CG1 4.31Å
391G65.5Low76.6Confident44 Ų4462.5 Ų62.545%0.45434%0.34SS..PPolyproline II helixtrans-68.8166.6175.100000113.7T389 R401T389-G391 VanDerWaalsContact C-N 3.27Å; T389-G391 PolarHBondContact O-N 3.24Å; G391-R401 PolarHBondContact O-NE 2.78Å; G391-R401 PolarHBondContact O-NH2 2.9Å
392E61.8Low76.2Confident156 Ų15662.2 Ų62.273%0.72934%0.339SS*.PPolyproline II helixtrans-59.8148.9171.1-68.4-176.2174.700110.4S394E392-S394 PolarHBondContact O-N 2.8Å; E392-S394 VanDerWaalsContact O-N 3.08Å
393Q59.1Low76Confident136 Ų13665.4 Ų65.464%0.63636%0.356SS*.PPolyproline II helixtrans-56118.8177.7-87.2178.5-7.700110.1R401Q393-R401 HydrophobicContact CG-CB 3.94Å
394S61.6Low75.9Confident40 Ų4064.4 Ų64.428%0.2835%0.35SS..PPolyproline II helixtrans-79.5141.4167.374.60000108.5Y322 E392 F396Y322-S394 PolarHBondContact O-OG 3.45Å; Y322-S394 VanDerWaalsContact O-OG 3.06Å; E392-S394 PolarHBondContact O-N 2.8Å; E392-S394 VanDerWaalsContact O-N 3.08Å; S394-F396 PolarHBondContact O-N 3.02Å
395T61.2Low75.9Confident145 Ų14563.5 Ų63.589%0.8934%0.34SS*.  trans-77.33172480000112.2N397T395-N397 PolarHBondContact O-N 2.81Å
396F63.2Low75.8Confident79 Ų7964.5 Ų64.535%0.34634%0.344SS..G310 helixtrans-71.1115.2-179.2-165.1-101.9000109.1Y322 S394 D398Y322-F396 AromaticContact CD1-CD1 3.75Å; Y322-F396 HydrophobicContact CD1-CD1 3.75Å; Y322-F396 AromaticContact CD1-CE1 3.88Å; Y322-F396 HydrophobicContact CD1-CE1 3.88Å; Y322-F396 HydrophobicContact CD1-CG 4.26Å; Y322-F396 AromaticContact CD2-CD1 3.65Å; Y322-F396 HydrophobicContact CD2-CD1 3.65Å; Y322-F396 AromaticContact CD2-CE1 3.4Å; Y322-F396 HydrophobicContact CD2-CE1 3.4Å; Y322-F396 VanDerWaalsContact CD2-CE1 3.4Å; Y322-F396 HydrophobicContact CD2-CZ 4.44Å; Y322-F396 HydrophobicContact CE1-CD1 4.22Å; Y322-F396 AromaticContact CE1-CE1 3.91Å; Y322-F396 HydrophobicContact CE1-CE1 3.91Å; Y322-F396 HydrophobicContact CE1-CZ 4.17Å; Y322-F396 HydrophobicContact CE2-CD1 4.14Å; Y322-F396 AromaticContact CE2-CE1 3.43Å; Y322-F396 HydrophobicContact CE2-CE1 3.43Å; Y322-F396 VanDerWaalsContact CE2-CE1 3.43Å; Y322-F396 HydrophobicContact CE2-CZ 4.11Å; Y322-F396 AromaticContact CG-CD1 3.42Å; Y322-F396 HydrophobicContact CG-CD1 3.42Å; Y322-F396 VanDerWaalsContact CG-CD1 3.42Å; Y322-F396 AromaticContact CG-CE1 3.62Å; Y322-F396 HydrophobicContact CG-CE1 3.62Å; Y322-F396 HydrophobicContact CG-CG 4.29Å; Y322-F396 AromaticContact CZ-CE1 3.69Å; Y322-F396 AromaticContact CZ-CZ 3.95Å; S394-F396 PolarHBondContact O-N 3.02Å; F396-D398 PolarHBondContact O-N 2.92Å
397N55.5Low75.8Confident101 Ų10164.9 Ų64.954%0.5435%0.346SS..G310 helixtrans57.634.7177.8-70.1-18.5000117.1S358 T395 Y399S358-N397 VanDerWaalsContact CA-ND2 3.32Å; S358-N397 WeakPolarHBondContact CA-ND2 3.47Å; S358-N397 WeakPolarHBondContact CB-ND2 3.3Å; S358-N397 PolarHBondContact O-ND2 2.85Å; T395-N397 PolarHBondContact O-N 2.81Å; N397-Y399 PolarHBondContact O-N 3.34Å; N397-Y399 VanDerWaalsContact O-N 3.13Å
398D64.5Low75.8Confident151 Ų15163.6 Ų63.681%0.80734%0.337SS*.G310 helixtrans5730.4175-143.814.6000112.6F396 Q400F396-D398 PolarHBondContact O-N 2.92Å; D398-Q400 PolarHBondContact O-N 2.88Å; D398-Q400 VanDerWaalsContact O-N 3.14Å
399Y63.9Low76.1Confident34 Ų3463.5 Ų63.513%0.13333%0.331CS..  trans-61.4115-178.3177.8-100.3000110.8D319 G323 S324 N397 P402D319-Y399 HydrophobicContact CB-CE2 4.42Å; D319-Y399 WeakPolarHBondContact OD1-CE2 3.21Å; D319-Y399 PolarHBondContact OD1-OH 3.38Å; D319-Y399 PolarHBondContact OD2-OH 3.19Å; G323-Y399 VanDerWaalsContact CA-CZ 3.47Å; S324-Y399 PolarHBondContact N-OH 2.9Å; S324-Y399 PolarHBondContact OG-OH 2.82Å; N397-Y399 PolarHBondContact O-N 3.34Å; N397-Y399 VanDerWaalsContact O-N 3.13Å; Y399-P402 WeakPolarHBondContact OH-CD 3.49Å
400Q71.4Confident76.3Confident116 Ų11667.5 Ų67.554%0.54235%0.348SS..PPolyproline II helixtrans-88.5122171.5-67.3-168.1-8.800109.6D398D398-Q400 PolarHBondContact O-N 2.88Å; D398-Q400 VanDerWaalsContact O-N 3.14Å
401R81.6Confident76.8Confident66 Ų6669 Ų6925%0.24936%0.364CS..PPolyproline II helixtrans-49.4132.7172.8-167.5-172.8-121.9-164.1-1.3110.5L390 G391 Q393L390-R401 VanDerWaalsContact C-NH2 3.35Å; L390-R401 PolarHBondContact O-NH2 3.08Å; G391-R401 PolarHBondContact O-NE 2.78Å; G391-R401 PolarHBondContact O-NH2 2.9Å; Q393-R401 HydrophobicContact CG-CB 3.94Å
402P89.6Confident77.9Confident7 Ų767.3 Ų67.35%0.04535%0.345CS..PPolyproline II helixtrans-53.3143.3171.8-29.835.7000111.3A39 Y41 L283 D319 Y399A39-P402 HydrophobicContact CB-CB 4.25Å; A39-P402 HydrophobicContact CB-CG 4.02Å; A39-P402 WeakPolarHBondContact O-CA 3.47Å; A39-P402 WeakPolarHBondContact O-CB 3.25Å; Y41-P402 HydrophobicContact CD2-CB 3.82Å; Y41-P402 HydrophobicContact CD2-CG 4.47Å; Y41-P402 HydrophobicContact CE2-CB 4.03Å; Y41-P402 HydrophobicContact CE2-CG 4.18Å; L283-P402 HydrophobicContact CD1-CB 4.38Å; L283-P402 HydrophobicContact CD1-CG 4.31Å; D319-P402 WeakPolarHBondContact OD2-CG 3.33Å; Y399-P402 WeakPolarHBondContact OH-CD 3.49Å
403L90.6Very high79.1Confident69 Ų6961.4 Ų61.436%0.36132%0.316SS..EExtended strand (participates in β ladder)trans-66.7153.4172.4-67.2170.3000109.6A39 F40 Y41 Y405A39-L403 PolarHBondContact O-N 2.98Å; F40-L403 CarbonylContact C-O 3.46Å; F40-L403 WeakPolarHBondContact CA-O 3.44Å; F40-L403 HydrophobicContact CB-CB 4.37Å; Y41-L403 PolarHBondContact N-O 3.34Å; L403-Y405 HydrophobicContact CB-CE2 4.09Å
404I92.1Very high80.3Confident43 Ų4358.1 Ų58.122%0.22130%0.303CS..EExtended strand (participates in β ladder)trans-120.8119.7178.5-50.3179.1000108.2Y41 T73 F281 L390 Y406Y41-I404 HydrophobicContact CD2-CG1 4.48Å; T73-I404 HydrophobicContact CG2-CD1 3.57Å; F281-I404 HydrophobicContact CE1-CG2 4.01Å; L390-I404 HydrophobicContact CD1-CD1 4.23Å; L390-I404 HydrophobicContact CD2-CD1 3.74Å; L390-I404 HydrophobicContact CD2-CG1 4.31Å; I404-Y406 HydrophobicContact CG2-CD1 4.13Å; I404-Y406 HydrophobicContact CG2-CE1 3.65Å; I404-Y406 HydrophobicContact CG2-CE2 4.08Å
405Y92.4Very high81.5Confident72 Ų7260.5 Ų60.528%0.28231%0.31SS..EExtended strand (participates in β ladder)trans-101.5122.1171.8-62.9-85000108.5H32 F40 Y41 V42 G43 L403H32-Y405 AromaticContact NE2-CE2 3.56Å; H32-Y405 AromaticContact NE2-CZ 3.6Å; H32-Y405 PolarHBondContact NE2-OH 3.02Å; F40-Y405 HydrophobicContact CB-CD2 4.13Å; F40-Y405 HydrophobicContact CB-CE2 3.83Å; F40-Y405 AromaticContact CD2-CD2 3.89Å; F40-Y405 HydrophobicContact CD2-CD2 3.89Å; F40-Y405 HydrophobicContact CD2-CE2 4.12Å; F40-Y405 HydrophobicContact CG-CD2 4.27Å; F40-Y405 HydrophobicContact CG-CE2 4.07Å; Y41-Y405 PolarHBondContact O-N 3.3Å; V42-Y405 CarbonylContact C-O 3.6Å; V42-Y405 WeakPolarHBondContact CA-O 3.49Å; G43-Y405 PolarHBondContact N-O 3.26Å; L403-Y405 HydrophobicContact CB-CE2 4.09Å
406Y92.4Very high82.6Confident21 Ų2153.7 Ų53.78%0.08227%0.268CS..EExtended strand (participates in β ladder)trans-95.4139.3176.7-65.9-65.1000110.8Y10 G13 G43 L45 T73 F281 I404Y10-Y406 HydrophobicContact CD1-CE2 4.3Å; G13-Y406 PolarHBondContact N-O 3.08Å; G43-Y406 WeakPolarHBondContact O-CA 3.42Å; L45-Y406 HydrophobicContact CD1-CD1 3.95Å; L45-Y406 HydrophobicContact CD1-CG 3.98Å; L45-Y406 HydrophobicContact CD2-CD1 3.62Å; L45-Y406 HydrophobicContact CD2-CE1 3.94Å; L45-Y406 HydrophobicContact CD2-CG 4.48Å; L45-Y406 HydrophobicContact CG-CD1 3.87Å; L45-Y406 HydrophobicContact CG-CG 4.35Å; T73-Y406 WeakPolarHBondContact CB-OH 3.45Å; T73-Y406 PolarHBondContact OG1-OH 3.27Å; F281-Y406 AromaticContact CE1-CE1 3.93Å; F281-Y406 HydrophobicContact CE1-CE1 3.93Å; F281-Y406 HydrophobicContact CZ-CE1 4.02Å; I404-Y406 HydrophobicContact CG2-CD1 4.13Å; I404-Y406 HydrophobicContact CG2-CE1 3.65Å; I404-Y406 HydrophobicContact CG2-CE2 4.08Å
407M92.1Very high83.7Confident7 Ų754 Ų543%0.03427%0.27CS..EExtended strand (participates in β ladder)trans-133.2157.1173.760.3124.6-65.300111.1G13 L15 L21 V42 G43 D44 L45G13-M407 VanDerWaalsContact O-CA 3.3Å; G13-M407 WeakPolarHBondContact O-CA 3.26Å; L15-M407 HydrophobicContact CD1-CB 4.42Å; L15-M407 HydrophobicContact CD1-CE 3.66Å; L15-M407 HydrophobicContact CD1-SD 3.53Å; L15-M407 VanDerWaalsContact CD1-SD 3.53Å; L15-M407 HydrophobicContact CG-CB 4.36Å; L15-M407 HydrophobicContact CG-CE 4.29Å; L15-M407 HydrophobicContact CG-SD 4.43Å; L21-M407 HydrophobicContact CD1-SD 4.06Å; V42-M407 HydrophobicContact CG1-CG 3.9Å; G43-M407 PolarHBondContact O-N 3.09Å; D44-M407 HydrophobicContact CB-CE 4Å; D44-M407 HydrophobicContact CB-CG 4.37Å; D44-M407 HydrophobicContact CB-SD 4.04Å; D44-M407 WeakPolarHBondContact OD1-CE 3.28Å; L45-M407 PolarHBondContact N-O 2.92Å
408I90.7Very high85.1Confident2 Ų255.6 Ų55.61%0.0128%0.279CS..EExtended strand (participates in β ladder)trans-144142.7167.3-167.3166.3000109I12 G13 L14 L15 D412 W413 M416 F432I12-I408 HydrophobicContact CG2-CB 4.15Å; I12-I408 HydrophobicContact CG2-CG2 3.69Å; G13-I408 PolarHBondContact O-N 2.72Å; L14-I408 HydrophobicContact CD1-CG2 3.74Å; L15-I408 PolarHBondContact N-O 3.38Å; I408-D412 HydrophobicContact CD1-CB 4.24Å; I408-D412 HydrophobicContact CG1-CB 3.9Å; I408-W413 HydrophobicContact CD1-CB 4.13Å; I408-W413 HydrophobicContact CD1-CE3 4.38Å; I408-W413 HydrophobicContact CG1-CB 4.32Å; I408-W413 HydrophobicContact CG2-CB 4.16Å; I408-M416 HydrophobicContact CD1-SD 3.32Å; I408-M416 WeakPolarHBondContact CD1-SD 3.37Å; I408-F432 HydrophobicContact CG2-CD1 4.02Å; I408-F432 HydrophobicContact CG2-CE1 3.91Å
409S90.1Very high85.8Confident34 Ų3451.5 Ų51.524%0.23827%0.266CS..EExtended strand (participates in β ladder)trans-72.8151.2173730000110.9G411 D412 W413S409-G411 VanDerWaalsContact C-N 3.26Å; S409-G411 PolarHBondContact O-N 3.49Å; S409-D412 PolarHBondContact O-N 3.03Å; S409-D412 WeakPolarHBondContact OG-CB 3.46Å; S409-D412 PolarHBondContact OG-N 3.17Å; S409-D412 VanDerWaalsContact OG-N 3.16Å; S409-D412 PolarHBondContact OG-OD1 3.43Å; S409-D412 PolarHBondContact OG-OD2 2.87Å; S409-W413 WeakPolarHBondContact O-CB 3.41Å; S409-W413 PolarHBondContact O-N 3.43Å
410F86.7Confident86.7Confident88 Ų8851.4 Ų51.439%0.38628%0.276SS..Hα-helixtrans-55.5-42.5175.2-173.1-90000112.3L14 L15 W413 D414L14-F410 HydrophobicContact CD1-CD2 4.48Å; L14-F410 HydrophobicContact CD2-CD2 3.94Å; L14-F410 HydrophobicContact CD2-CE2 4.43Å; L14-F410 HydrophobicContact CG-CD2 4.3Å; L15-F410 WeakPolarHBondContact O-CB 3.48Å; L15-F410 PolarHBondContact O-N 3.32Å; F410-W413 PolarHBondContact O-N 2.57Å; F410-D414 WeakPolarHBondContact O-CB 3.37Å; F410-D414 PolarHBondContact O-N 2.86Å
411G86.6Confident87.2Confident37 Ų3747 Ų4738%0.38126%0.255SS..Hα-helixtrans-61-46.6177.600000112.9S409 W413 D414 E415S409-G411 VanDerWaalsContact C-N 3.26Å; S409-G411 PolarHBondContact O-N 3.49Å; G411-W413 VanDerWaalsContact C-N 3.29Å; G411-W413 PolarHBondContact O-N 3.09Å; G411-D414 PolarHBondContact O-N 2.8Å; G411-E415 WeakPolarHBondContact O-CG 3.4Å; G411-E415 PolarHBondContact O-N 2.84Å
412D88.6Confident87.1Confident10 Ų1045.8 Ų45.85%0.05326%0.255CS..Hα-helixtrans-67.1-34.5179.3-62.3-18.8000111.8K50 I408 S409 M416K50-D412 WeakPolarHBondContact CE-OD1 3.29Å; K50-D412 IonicContact NZ-OD1 3.03Å; K50-D412 PolarHBondContact NZ-OD1 3.35Å; K50-D412 IonicContact NZ-OD2 2.62Å; K50-D412 PolarHBondContact NZ-OD2 3.45Å; I408-D412 HydrophobicContact CD1-CB 4.24Å; I408-D412 HydrophobicContact CG1-CB 3.9Å; S409-D412 PolarHBondContact O-N 3.03Å; S409-D412 WeakPolarHBondContact OG-CB 3.46Å; S409-D412 PolarHBondContact OG-N 3.17Å; S409-D412 VanDerWaalsContact OG-N 3.16Å; S409-D412 PolarHBondContact OG-OD1 3.43Å; S409-D412 PolarHBondContact OG-OD2 2.87Å; D412-M416 VanDerWaalsContact O-CG 3.29Å; D412-M416 WeakPolarHBondContact O-CG 3.5Å; D412-M416 PolarHBondContact O-N 3.01Å
413W86.8Confident86.6Confident31 Ų3150.2 Ų50.212%0.11729%0.287CS..Hα-helixtrans-66.7-43.6175.2173.3-113.6000112.2L14 I408 S409 F410 G411 M416 Q417 T422 F432L14-W413 HydrophobicContact CD1-CB 3.59Å; L14-W413 HydrophobicContact CD1-CG 3.69Å; I408-W413 HydrophobicContact CD1-CB 4.13Å; I408-W413 HydrophobicContact CD1-CE3 4.38Å; I408-W413 HydrophobicContact CG1-CB 4.32Å; I408-W413 HydrophobicContact CG2-CB 4.16Å; S409-W413 WeakPolarHBondContact O-CB 3.41Å; S409-W413 PolarHBondContact O-N 3.43Å; F410-W413 PolarHBondContact O-N 2.57Å; G411-W413 VanDerWaalsContact C-N 3.29Å; G411-W413 PolarHBondContact O-N 3.09Å; W413-M416 HydrophobicContact CE3-SD 4.44Å; W413-M416 WeakPolarHBondContact O-CB 3.48Å; W413-M416 PolarHBondContact O-N 3.24Å; W413-Q417 HydrophobicContact CD2-CG 4.44Å; W413-Q417 HydrophobicContact CZ2-CG 4.22Å; W413-Q417 WeakPolarHBondContact O-CG 3.44Å; W413-Q417 PolarHBondContact O-N 2.89Å; W413-T422 HydrophobicContact CE3-CG2 3.88Å; W413-T422 HydrophobicContact CH2-CG2 3.36Å; W413-T422 HydrophobicContact CZ2-CG2 4.13Å; W413-T422 HydrophobicContact CZ3-CG2 3.2Å; W413-F432 HydrophobicContact CD2-CD1 4.12Å; W413-F432 HydrophobicContact CD2-CE1 4.11Å; W413-F432 AromaticContact CE3-CD1 3.92Å; W413-F432 HydrophobicContact CE3-CD1 3.92Å; W413-F432 AromaticContact CE3-CE1 3.44Å; W413-F432 HydrophobicContact CE3-CE1 3.44Å; W413-F432 VanDerWaalsContact CE3-CE1 3.44Å; W413-F432 HydrophobicContact CE3-CE2 4.15Å; W413-F432 HydrophobicContact CE3-CG 4.45Å; W413-F432 AromaticContact CE3-CZ 3.6Å; W413-F432 HydrophobicContact CE3-CZ 3.6Å; W413-F432 HydrophobicContact CH2-CD1 4.18Å; W413-F432 AromaticContact CH2-CD2 3.35Å; W413-F432 HydrophobicContact CH2-CD2 3.35Å; W413-F432 AromaticContact CH2-CE1 3.96Å; W413-F432 HydrophobicContact CH2-CE1 3.96Å; W413-F432 AromaticContact CH2-CE2 3.11Å; W413-F432 HydrophobicContact CH2-CE2 3.11Å; W413-F432 AromaticContact CH2-CG 3.91Å; W413-F432 HydrophobicContact CH2-CG 3.91Å; W413-F432 AromaticContact CH2-CZ 3.46Å; W413-F432 HydrophobicContact CH2-CZ 3.46Å; W413-F432 VanDerWaalsContact CH2-CZ 3.46Å; W413-F432 HydrophobicContact CZ2-CD1 4.36Å; W413-F432 AromaticContact CZ2-CD2 3.73Å; W413-F432 HydrophobicContact CZ2-CD2 3.73Å; W413-F432 AromaticContact CZ2-CE2 3.98Å; W413-F432 HydrophobicContact CZ2-CE2 3.98Å; W413-F432 AromaticContact CZ2-CG 3.96Å; W413-F432 HydrophobicContact CZ2-CG 3.96Å; W413-F432 HydrophobicContact CZ2-CZ 4.39Å; W413-F432 AromaticContact CZ3-CD1 3.96Å; W413-F432 HydrophobicContact CZ3-CD1 3.96Å; W413-F432 AromaticContact CZ3-CD2 3.82Å; W413-F432 HydrophobicContact CZ3-CD2 3.82Å; W413-F432 AromaticContact CZ3-CE1 3.36Å; W413-F432 HydrophobicContact CZ3-CE1 3.36Å; W413-F432 AromaticContact CZ3-CE2 3.23Å; W413-F432 HydrophobicContact CZ3-CE2 3.23Å; W413-F432 HydrophobicContact CZ3-CG 4.16Å; W413-F432 AromaticContact CZ3-CZ 2.97Å; W413-F432 HydrophobicContact CZ3-CZ 2.97Å
414D85.9Confident86.3Confident68 Ų6849.9 Ų49.936%0.36429%0.285SS..Hα-helixtrans-60.5-45.7175.3-164.759.5000110.7F410 G411 M416 Q417 D418F410-D414 WeakPolarHBondContact O-CB 3.37Å; F410-D414 PolarHBondContact O-N 2.86Å; G411-D414 PolarHBondContact O-N 2.8Å; D414-M416 VanDerWaalsContact C-N 3.3Å; D414-M416 PolarHBondContact O-N 3.45Å; D414-Q417 WeakPolarHBondContact O-CB 3.44Å; D414-Q417 PolarHBondContact O-N 2.64Å; D414-D418 PolarHBondContact O-N 3.04Å
415E85.7Confident85.7Confident90 Ų9053.3 Ų53.342%0.42131%0.308SS..Hα-helixtrans-58.9-39.6173.7-72.9-177.8-168.100112.6G411 Q417 A419G411-E415 WeakPolarHBondContact O-CG 3.4Å; G411-E415 PolarHBondContact O-N 2.84Å; E415-Q417 VanDerWaalsContact C-N 3.35Å; E415-A419 WeakPolarHBondContact O-CB 3.14Å; E415-A419 PolarHBondContact O-N 3.3Å
416M85.3Confident85.1Confident1 Ų151.3 Ų51.31%0.00530%0.302CS..Hα-helixtrans-65-37.8174.3-74.5177.676.700112.4V49 I408 D412 W413 D414 G420 I421 T422 M427V49-M416 HydrophobicContact CG1-CG 4.16Å; V49-M416 HydrophobicContact CG2-CE 4.07Å; V49-M416 HydrophobicContact CG2-CG 3.88Å; V49-M416 HydrophobicContact CG2-SD 3.72Å; I408-M416 HydrophobicContact CD1-SD 3.32Å; I408-M416 WeakPolarHBondContact CD1-SD 3.37Å; D412-M416 VanDerWaalsContact O-CG 3.29Å; D412-M416 WeakPolarHBondContact O-CG 3.5Å; D412-M416 PolarHBondContact O-N 3.01Å; W413-M416 HydrophobicContact CE3-SD 4.44Å; W413-M416 WeakPolarHBondContact O-CB 3.48Å; W413-M416 PolarHBondContact O-N 3.24Å; D414-M416 VanDerWaalsContact C-N 3.3Å; D414-M416 PolarHBondContact O-N 3.45Å; M416-G420 PolarHBondContact O-N 2.94Å; M416-I421 HydrophobicContact CB-CB 4.41Å; M416-I421 HydrophobicContact CE-CG2 3.69Å; M416-I421 HydrophobicContact CG-CD1 4.4Å; M416-I421 WeakPolarHBondContact O-CB 3.46Å; M416-I421 PolarHBondContact O-N 2.84Å; M416-T422 HydrophobicContact CB-CG2 3.92Å; M416-M427 HydrophobicContact CE-CE 3.89Å
417Q85.4Confident84.6Confident86 Ų8650.8 Ų50.840%0.40230%0.301SS..Hα-helixtrans-66.7-46.3176.9-70.6-169.70.600111.3W413 D414 E415 A419 G420 T422W413-Q417 HydrophobicContact CD2-CG 4.44Å; W413-Q417 HydrophobicContact CZ2-CG 4.22Å; W413-Q417 WeakPolarHBondContact O-CG 3.44Å; W413-Q417 PolarHBondContact O-N 2.89Å; D414-Q417 WeakPolarHBondContact O-CB 3.44Å; D414-Q417 PolarHBondContact O-N 2.64Å; E415-Q417 VanDerWaalsContact C-N 3.35Å; Q417-A419 VanDerWaalsContact C-N 3.26Å; Q417-A419 PolarHBondContact O-N 2.87Å; Q417-G420 WeakPolarHBondContact O-CA 3.12Å; Q417-G420 PolarHBondContact O-N 3.1Å; Q417-T422 HydrophobicContact CB-CG2 4.41Å; Q417-T422 HydrophobicContact CG-CG2 3.68Å
418D84.2Confident84Confident135 Ų13557.8 Ų57.872%0.72233%0.331SS*.Hα-helixtrans-62.2-35.3178.6-84.4-4.7000112.2D414 G420D414-D418 PolarHBondContact O-N 3.04Å; D418-G420 PolarHBondContact O-N 2.92Å
419A80.8Confident83.6Confident64 Ų6459.1 Ų59.153%0.52934%0.338SS..THydrogen-bonded Turntrans-74.1-417300000113.8E415 Q417 I421E415-A419 WeakPolarHBondContact O-CB 3.14Å; E415-A419 PolarHBondContact O-N 3.3Å; Q417-A419 VanDerWaalsContact C-N 3.26Å; Q417-A419 PolarHBondContact O-N 2.87Å; A419-I421 HydrophobicContact CB-CD1 3.75Å; A419-I421 HydrophobicContact CB-CG1 3.88Å; A419-I421 PolarHBondContact O-N 3.23Å
420G81.3Confident83.1Confident33 Ų3358.2 Ų58.234%0.3433%0.33SS..THydrogen-bonded Turntrans74.75.3-179.400000114.9M416 Q417 D418 T422 S423M416-G420 PolarHBondContact O-N 2.94Å; Q417-G420 WeakPolarHBondContact O-CA 3.12Å; Q417-G420 PolarHBondContact O-N 3.1Å; D418-G420 PolarHBondContact O-N 2.92Å; G420-T422 VanDerWaalsContact C-N 3.31Å; G420-T422 PolarHBondContact O-N 2.81Å; G420-S423 PolarHBondContact O-N 3.41Å; G420-S423 PolarHBondContact O-OG 3.42Å
421I82.8Confident82.7Confident22 Ų2258.9 Ų58.911%0.11333%0.333CS..G310 helixtrans-62.6-39.5-175-64.9168.9000110.6T82 L83 M416 A419 S423 D424 M427T82-I421 HydrophobicContact CG2-CB 4.36Å; T82-I421 HydrophobicContact CG2-CG2 3.49Å; T82-I421 VanDerWaalsContact CG2-CG2 3.49Å; T82-I421 WeakPolarHBondContact CG2-O 3.27Å; L83-I421 HydrophobicContact CD2-CD1 3.57Å; L83-I421 HydrophobicContact CD2-CG1 4.4Å; M416-I421 HydrophobicContact CB-CB 4.41Å; M416-I421 HydrophobicContact CE-CG2 3.69Å; M416-I421 HydrophobicContact CG-CD1 4.4Å; M416-I421 WeakPolarHBondContact O-CB 3.46Å; M416-I421 PolarHBondContact O-N 2.84Å; A419-I421 HydrophobicContact CB-CD1 3.75Å; A419-I421 HydrophobicContact CB-CG1 3.88Å; A419-I421 PolarHBondContact O-N 3.23Å; I421-S423 PolarHBondContact O-N 3.47Å; I421-D424 WeakPolarHBondContact O-CB 3.39Å; I421-D424 PolarHBondContact O-N 3.41Å; I421-M427 WeakPolarHBondContact O-CG 3.42Å
422T80.2Confident82.3Confident41 Ų4159.6 Ų59.625%0.25233%0.325SS..G310 helixtrans-69.1-16-175.563.10000114W413 M416 Q417 G420W413-T422 HydrophobicContact CE3-CG2 3.88Å; W413-T422 HydrophobicContact CH2-CG2 3.36Å; W413-T422 HydrophobicContact CZ2-CG2 4.13Å; W413-T422 HydrophobicContact CZ3-CG2 3.2Å; M416-T422 HydrophobicContact CB-CG2 3.92Å; Q417-T422 HydrophobicContact CB-CG2 4.41Å; Q417-T422 HydrophobicContact CG-CG2 3.68Å; G420-T422 VanDerWaalsContact C-N 3.31Å; G420-T422 PolarHBondContact O-N 2.81Å
423S78.2Confident81.7Confident101 Ų10162.5 Ų62.571%0.70634%0.343SS*.G310 helixtrans-87.9-5.7178.171.60000113.7G420 I421G420-S423 PolarHBondContact O-N 3.41Å; G420-S423 PolarHBondContact O-OG 3.42Å; I421-S423 PolarHBondContact O-N 3.47Å
424D83.7Confident81Confident62 Ų6265 Ų6533%0.33236%0.364SS..SBendtrans-68.6142.2178.7-162.1-61.5000111.6T82 I421 L426 M427T82-D424 HydrophobicContact CG2-CB 3.49Å; T82-D424 VanDerWaalsContact CG2-CB 3.49Å; I421-D424 WeakPolarHBondContact O-CB 3.39Å; I421-D424 PolarHBondContact O-N 3.41Å; D424-L426 PolarHBondContact O-N 3.29Å; D424-L426 WeakPolarHBondContact OD1-CB 3.45Å; D424-L426 WeakPolarHBondContact OD1-CG 3.36Å; D424-L426 PolarHBondContact OD1-N 2.98Å; D424-M427 HydrophobicContact CB-CG 4.43Å; D424-M427 WeakPolarHBondContact O-CB 3.26Å; D424-M427 PolarHBondContact O-N 3.06Å
425T80.9Confident80Confident115 Ų11562.7 Ų62.771%0.70635%0.353SS*.G310 helixtrans-59.7-24.8175.955.60000114.2M427 K428T425-M427 PolarHBondContact O-N 3.02Å; T425-K428 WeakPolarHBondContact O-CB 3.21Å; T425-K428 WeakPolarHBondContact O-CD 3.47Å; T425-K428 VanDerWaalsContact O-CG 3.29Å; T425-K428 WeakPolarHBondContact O-CG 3.45Å; T425-K428 PolarHBondContact O-N 3.39Å
426L79.8Confident78.2Confident29 Ų2964.2 Ų64.215%0.15237%0.372CS..G310 helixtrans-68.2-22.7174-68.3178.7000112.3T82 L101 I103 D424 K428T82-L426 WeakPolarHBondContact OG1-CB 3.38Å; L101-L426 WeakPolarHBondContact O-CD2 3.5Å; I103-L426 HydrophobicContact CD1-CD1 4.01Å; D424-L426 PolarHBondContact O-N 3.29Å; D424-L426 WeakPolarHBondContact OD1-CB 3.45Å; D424-L426 WeakPolarHBondContact OD1-CG 3.36Å; D424-L426 PolarHBondContact OD1-N 2.98Å; L426-K428 VanDerWaalsContact C-N 3.29Å; L426-K428 PolarHBondContact O-N 3Å
427M81.1Confident76.7Confident11 Ų1166 Ų665%0.05438%0.381CS..G310 helixtrans-84.92.6-179.4-65.9-65.7-67.400114I79 T82 M416 I421 D424 T425 N429 F430 F432I79-M427 HydrophobicContact CG1-CE 4.42Å; I79-M427 HydrophobicContact CG1-SD 4.17Å; T82-M427 HydrophobicContact CG2-CG 3.93Å; T82-M427 HydrophobicContact CG2-SD 4.35Å; M416-M427 HydrophobicContact CE-CE 3.89Å; I421-M427 WeakPolarHBondContact O-CG 3.42Å; D424-M427 HydrophobicContact CB-CG 4.43Å; D424-M427 WeakPolarHBondContact O-CB 3.26Å; D424-M427 PolarHBondContact O-N 3.06Å; T425-M427 PolarHBondContact O-N 3.02Å; M427-N429 PolarHBondContact O-N 2.65Å; M427-N429 VanDerWaalsContact O-N 3.1Å; M427-F430 HydrophobicContact CB-CD2 4.18Å; M427-F430 HydrophobicContact CE-CB 4.48Å; M427-F430 HydrophobicContact CE-CD2 3.45Å; M427-F430 VanDerWaalsContact CE-CD2 3.45Å; M427-F430 HydrophobicContact CE-CE2 3.82Å; M427-F430 HydrophobicContact CE-CG 4.08Å; M427-F430 PolarHBondContact O-N 2.67Å; M427-F430 VanDerWaalsContact O-N 3.14Å; M427-F430 HydrophobicContact SD-CD2 3.58Å; M427-F430 VanDerWaalsContact SD-CD2 3.58Å; M427-F430 HydrophobicContact SD-CE2 3.48Å; M427-F430 WeakPolarHBondContact SD-CE2 3.39Å; M427-F432 HydrophobicContact CE-CZ 4.27Å
428K80.4Confident74.3Confident153 Ų15370.4 Ų70.467%0.66540%0.402SS*.G310 helixtrans-61.6-21.3-173.569.6-177.2179.2179.30115.1T425 L426T425-K428 WeakPolarHBondContact O-CB 3.21Å; T425-K428 WeakPolarHBondContact O-CD 3.47Å; T425-K428 VanDerWaalsContact O-CG 3.29Å; T425-K428 WeakPolarHBondContact O-CG 3.45Å; T425-K428 PolarHBondContact O-N 3.39Å; L426-K428 VanDerWaalsContact C-N 3.29Å; L426-K428 PolarHBondContact O-N 3Å
429N80.7Confident72.1Confident31 Ų3169.6 Ų69.617%0.16640%0.397CS..G310 helixtrans-90-3.7-177.1-65-25.8000112.4N9 Y10 E78 M427 F431N9-N429 CarbonylContact C-O 3.49Å; N9-N429 WeakPolarHBondContact CA-O 3.47Å; Y10-N429 HydrophobicContact CD2-CB 3.94Å; Y10-N429 HydrophobicContact CE2-CB 3.82Å; Y10-N429 PolarHBondContact N-O 2.78Å; E78-N429 PolarHBondContact OE1-ND2 3.14Å; M427-N429 PolarHBondContact O-N 2.65Å; M427-N429 VanDerWaalsContact O-N 3.1Å; N429-F431 WeakPolarHBondContact O-CD2 3.48Å
430F79.2Confident69.8Low15 Ų1568.8 Ų68.87%0.06639%0.387CS..EExtended strand (participates in β ladder)trans-92.7125.2-179.4-65.9-71.7000112.3Y10 I12 L45 E78 I79 M427 F432Y10-F430 HydrophobicContact CD2-CD1 4.02Å; Y10-F430 AromaticContact CD2-CE1 3.89Å; Y10-F430 HydrophobicContact CD2-CE1 3.89Å; Y10-F430 HydrophobicContact CD2-CZ 4.39Å; Y10-F430 HydrophobicContact CG-CD1 4.39Å; Y10-F430 HydrophobicContact CG-CE1 4.35Å; I12-F430 HydrophobicContact CD1-CB 4Å; I12-F430 HydrophobicContact CD1-CD1 3.14Å; I12-F430 HydrophobicContact CD1-CE1 3.78Å; I12-F430 HydrophobicContact CD1-CG 3.83Å; I12-F430 HydrophobicContact CG1-CD1 3.93Å; L45-F430 HydrophobicContact CD1-CE1 4.24Å; E78-F430 HydrophobicContact CB-CE2 3.68Å; E78-F430 HydrophobicContact CB-CZ 3.81Å; E78-F430 VanDerWaalsContact OE2-CE2 3.24Å; E78-F430 WeakPolarHBondContact OE2-CE2 3.48Å; I79-F430 HydrophobicContact CD1-CE1 4.38Å; I79-F430 HydrophobicContact CD1-CZ 4.1Å; I79-F430 HydrophobicContact CG1-CE2 4.11Å; I79-F430 HydrophobicContact CG1-CZ 3.76Å; M427-F430 HydrophobicContact CB-CD2 4.18Å; M427-F430 HydrophobicContact CE-CB 4.48Å; M427-F430 HydrophobicContact CE-CD2 3.45Å; M427-F430 VanDerWaalsContact CE-CD2 3.45Å; M427-F430 HydrophobicContact CE-CE2 3.82Å; M427-F430 HydrophobicContact CE-CG 4.08Å; M427-F430 PolarHBondContact O-N 2.67Å; M427-F430 VanDerWaalsContact O-N 3.14Å; M427-F430 HydrophobicContact SD-CD2 3.58Å; M427-F430 VanDerWaalsContact SD-CD2 3.58Å; M427-F430 HydrophobicContact SD-CE2 3.48Å; M427-F430 WeakPolarHBondContact SD-CE2 3.39Å; F430-F432 HydrophobicContact CB-CD2 4.42Å; F430-F432 HydrophobicContact CB-CE2 3.55Å; F430-F432 HydrophobicContact CB-CZ 3.87Å; F430-F432 HydrophobicContact CG-CZ 4.46Å
431F79.9Confident67.6Low101 Ų10171.8 Ų71.844%0.44340%0.403SS..EExtended strand (participates in β ladder)trans-114.5107175.6-66.9-93.9000108.9N9 Y10 S11 I12 N429 V433N9-F431 HydrophobicContact CB-CD2 3.58Å; N9-F431 HydrophobicContact CB-CE2 3.41Å; N9-F431 VanDerWaalsContact CB-CE2 3.41Å; N9-F431 HydrophobicContact CB-CZ 4.35Å; N9-F431 WeakPolarHBondContact OD1-CE2 3.49Å; Y10-F431 PolarHBondContact O-N 2.75Å; S11-F431 WeakPolarHBondContact CA-O 3.48Å; I12-F431 PolarHBondContact N-O 3.46Å; N429-F431 WeakPolarHBondContact O-CD2 3.48Å; F431-V433 PolarHBondContact O-N 3.48Å
432F77.4Confident65.4Low52 Ų5278.1 Ų78.123%0.22843%0.432CS..EExtended strand (participates in β ladder)trans-82.9115.6178.1-62.2-89.4000109I12 I408 W413 M427 F430I12-F432 HydrophobicContact CB-CD1 3.86Å; I12-F432 HydrophobicContact CB-CE1 3.91Å; I12-F432 HydrophobicContact CD1-CD1 4.21Å; I12-F432 HydrophobicContact CD1-CE1 3.41Å; I12-F432 VanDerWaalsContact CD1-CE1 3.41Å; I12-F432 HydrophobicContact CD1-CE2 4.38Å; I12-F432 HydrophobicContact CD1-CZ 3.49Å; I12-F432 VanDerWaalsContact CD1-CZ 3.49Å; I12-F432 HydrophobicContact CG1-CE1 4.24Å; I12-F432 HydrophobicContact CG2-CD1 3.9Å; I12-F432 HydrophobicContact CG2-CE1 3.84Å; I408-F432 HydrophobicContact CG2-CD1 4.02Å; I408-F432 HydrophobicContact CG2-CE1 3.91Å; W413-F432 HydrophobicContact CD2-CD1 4.12Å; W413-F432 HydrophobicContact CD2-CE1 4.11Å; W413-F432 AromaticContact CE3-CD1 3.92Å; W413-F432 HydrophobicContact CE3-CD1 3.92Å; W413-F432 AromaticContact CE3-CE1 3.44Å; W413-F432 HydrophobicContact CE3-CE1 3.44Å; W413-F432 VanDerWaalsContact CE3-CE1 3.44Å; W413-F432 HydrophobicContact CE3-CE2 4.15Å; W413-F432 HydrophobicContact CE3-CG 4.45Å; W413-F432 AromaticContact CE3-CZ 3.6Å; W413-F432 HydrophobicContact CE3-CZ 3.6Å; W413-F432 HydrophobicContact CH2-CD1 4.18Å; W413-F432 AromaticContact CH2-CD2 3.35Å; W413-F432 HydrophobicContact CH2-CD2 3.35Å; W413-F432 AromaticContact CH2-CE1 3.96Å; W413-F432 HydrophobicContact CH2-CE1 3.96Å; W413-F432 AromaticContact CH2-CE2 3.11Å; W413-F432 HydrophobicContact CH2-CE2 3.11Å; W413-F432 AromaticContact CH2-CG 3.91Å; W413-F432 HydrophobicContact CH2-CG 3.91Å; W413-F432 AromaticContact CH2-CZ 3.46Å; W413-F432 HydrophobicContact CH2-CZ 3.46Å; W413-F432 VanDerWaalsContact CH2-CZ 3.46Å; W413-F432 HydrophobicContact CZ2-CD1 4.36Å; W413-F432 AromaticContact CZ2-CD2 3.73Å; W413-F432 HydrophobicContact CZ2-CD2 3.73Å; W413-F432 AromaticContact CZ2-CE2 3.98Å; W413-F432 HydrophobicContact CZ2-CE2 3.98Å; W413-F432 AromaticContact CZ2-CG 3.96Å; W413-F432 HydrophobicContact CZ2-CG 3.96Å; W413-F432 HydrophobicContact CZ2-CZ 4.39Å; W413-F432 AromaticContact CZ3-CD1 3.96Å; W413-F432 HydrophobicContact CZ3-CD1 3.96Å; W413-F432 AromaticContact CZ3-CD2 3.82Å; W413-F432 HydrophobicContact CZ3-CD2 3.82Å; W413-F432 AromaticContact CZ3-CE1 3.36Å; W413-F432 HydrophobicContact CZ3-CE1 3.36Å; W413-F432 AromaticContact CZ3-CE2 3.23Å; W413-F432 HydrophobicContact CZ3-CE2 3.23Å; W413-F432 HydrophobicContact CZ3-CG 4.16Å; W413-F432 AromaticContact CZ3-CZ 2.97Å; W413-F432 HydrophobicContact CZ3-CZ 2.97Å; M427-F432 HydrophobicContact CE-CZ 4.27Å; F430-F432 HydrophobicContact CB-CD2 4.42Å; F430-F432 HydrophobicContact CB-CE2 3.55Å; F430-F432 HydrophobicContact CB-CZ 3.87Å; F430-F432 HydrophobicContact CG-CZ 4.46Å
433V76.8Confident63.3Low71 Ų7182.9 Ų82.943%0.4346%0.456SS..EExtended strand (participates in β ladder)trans-108.6124.7176.6-171.90000106.7I12 L14 F431 S435I12-V433 PolarHBondContact O-N 3.19Å; L14-V433 PolarHBondContact N-O 3.13Å; F431-V433 PolarHBondContact O-N 3.48Å; V433-S435 PolarHBondContact O-N 3.17Å; V433-S435 VanDerWaalsContact O-N 3.08Å
434P72Confident61.2Low85 Ų8588.4 Ų88.455%0.55246%0.462SS*.EExtended strand (participates in β ladder)trans-51.5121.7169.7-23.933.5000108.3C436P434-C436 PolarHBondContact O-N 2.93Å
435S64Low58.8Low19 Ų1993.6 Ų93.613%0.13348%0.481CS..  trans-70101.6178.280.60000106.7L14 L15 V433 I437L14-S435 WeakPolarHBondContact O-CB 3.5Å; L14-S435 PolarHBondContact O-N 2.82Å; L14-S435 PolarHBondContact O-OG 3.28Å; L15-S435 WeakPolarHBondContact CD2-OG 3.29Å; V433-S435 PolarHBondContact O-N 3.17Å; V433-S435 VanDerWaalsContact O-N 3.08Å; S435-I437 PolarHBondContact O-N 3Å
436C49.3Very low56.3Low121 Ų12192.6 Ų92.682%0.81848%0.479SS*.  trans-71.962.5167.2-71.30000108.8P434 Q438P434-C436 PolarHBondContact O-N 2.93Å; C436-Q438 PolarHBondContact O-N 3.14Å
437I52.3Low54Low38 Ų3898.7 Ų98.720%0.19552%0.518CS..  trans-72.885.6163.3-56.5173.9000104.1L15 A19 V24 S435 L439L15-I437 HydrophobicContact CD2-CD1 3.94Å; A19-I437 HydrophobicContact CB-CD1 4.32Å; V24-I437 HydrophobicContact CG2-CD1 4.01Å; S435-I437 PolarHBondContact O-N 3Å; I437-L439 HydrophobicContact CG2-CD2 4.26Å; I437-L439 HydrophobicContact CG2-CG 4.18Å; I437-L439 PolarHBondContact O-N 3.43Å
438Q36.2Very low51.7Low180 Ų180102.1 Ų102.184%0.84155%0.548SS*.  trans-65.190.6167.3-79.3-171.9-24.700106.5C436 S440C436-Q438 PolarHBondContact O-N 3.14Å; Q438-S440 PolarHBondContact O-N 3.46Å
439L38.3Very low49.5Very low118 Ų118103.5 Ų103.562%0.61859%0.588SS**  trans-64.784.4161.1-70.8170.5000106.4I437 S441I437-L439 HydrophobicContact CG2-CD2 4.26Å; I437-L439 HydrophobicContact CG2-CG 4.18Å; I437-L439 PolarHBondContact O-N 3.43Å; L439-S441 PolarHBondContact O-N 3.35Å; L439-S441 VanDerWaalsContact O-N 3.14Å
440S32Very low47.9Very low47 Ų47107.1 Ų107.133%0.32961%0.609SS.*  trans-64.6116.1163.7102.20000105.1Q438 E442 D443Q438-S440 PolarHBondContact O-N 3.46Å; S440-E442 PolarHBondContact O-N 3.02Å; S440-D443 PolarHBondContact O-N 2.99Å; S440-D443 WeakPolarHBondContact OG-CB 3.45Å; S440-D443 PolarHBondContact OG-N 2.94Å; S440-D443 PolarHBondContact OG-OD2 3.03Å
441S35.3Very low46.2Very low96 Ų96111.9 Ų111.967%0.67164%0.637SS**THydrogen-bonded Turntrans-62.7-2169.848.30000112.3L439L439-S441 PolarHBondContact O-N 3.35Å; L439-S441 VanDerWaalsContact O-N 3.14Å
442E35.1Very low44.4Very low154 Ų154112.6 Ų112.672%0.7265%0.648SS**THydrogen-bonded Turntrans-102.8-15.6-175.2-66.5-170.8156.300113.6S440 R444 F445S440-E442 PolarHBondContact O-N 3.02Å; E442-R444 PolarHBondContact O-N 2.96Å; E442-F445 WeakPolarHBondContact O-CD2 3.33Å
443D36.6Very low42.4Very low142 Ų142116.1 Ų116.176%0.75967%0.673SS**SBendtrans-79.5-1.6171.2-71.3-48.3000113.1S440 F445S440-D443 PolarHBondContact O-N 2.99Å; S440-D443 WeakPolarHBondContact OG-CB 3.45Å; S440-D443 PolarHBondContact OG-N 2.94Å; S440-D443 PolarHBondContact OG-OD2 3.03Å; D443-F445 PolarHBondContact O-N 3Å; D443-F445 VanDerWaalsContact O-N 3.14Å
444R34.6Very low40.3Very low217 Ų217118.9 Ų118.982%0.81969%0.688SS**SBendtrans-80.956.6160.4-66.2-168.6-136.8-160.91.1111.2E442E442-R444 PolarHBondContact O-N 2.96Å
445F32.6Very low38.2Very low170 Ų170121.2 Ų121.275%0.74670%0.697SS**  trans-139.2125.2170.2-82-74.4000115.4E442 D443E442-F445 WeakPolarHBondContact O-CD2 3.33Å; D443-F445 PolarHBondContact O-N 3Å; D443-F445 VanDerWaalsContact O-N 3.14Å
446S28.7Very low36.3Very low95 Ų95128.5 Ų128.566%0.66474%0.738SS**  trans83.480.4136.1-171.90000118.8
447T31.2Very low35.3Very low156 Ų156129.1 Ų129.196%0.95773%0.731SS**  trans-88.483.2138.252.60000109.1
448A33.6Very low33.9Very low83 Ų83136.7 Ų136.769%0.68678%0.776SS**  trans-13989.3162.300000108.7
449A32.9Very low33.7Very low182 Ų182132.7 Ų132.7100%1.50477%0.77SS**  trans-169.40143.300000108.5

Retrieved 449 of 449 residues in 319.9 ms (Link to these results)