A0A093HVA8_STRCA Loading...

Calpain-5

AlphaFold DB , UniProt , Accession A0A093HVA8, Species STRCA (Struthio camelus australis), Gene n/a, Length 644 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M29.5Very low79Confident244 Ų24495.7 Ų95.7100%1.20253%0.529SS*.  0114.90-69.5175.5-177.400106.1S3M1-S3 PolarHBondContact O-N 3.12Å; M1-S3 VanDerWaalsContact O-N 3.14Å
2S36.2Very low80.5Confident126 Ų12695.4 Ų95.488%0.88152%0.518SS*.  trans-62.4113.7173.2-172.40000106.8S4S2-S4 PolarHBondContact O-N 3.36Å
3S55.3Low81.7Confident71 Ų7188.3 Ų88.350%0.49748%0.479SS..PPolyproline II helixtrans-61.5123.2171.150.90000107.3M1 V5M1-S3 PolarHBondContact O-N 3.12Å; M1-S3 VanDerWaalsContact O-N 3.14Å; S3-V5 PolarHBondContact O-N 3.44Å
4S80.3Confident82.7Confident97 Ų9789.6 Ų89.668%0.67848%0.481SS*.PPolyproline II helixtrans-53.4130.4171.548.70000109.4S2S2-S4 PolarHBondContact O-N 3.36Å
5V90.2Very high83.7Confident53 Ų5390.6 Ų90.632%0.32148%0.481SS..PPolyproline II helixtrans-72.6128173.71800000107.7S3 R124 W131 E133S3-V5 PolarHBondContact O-N 3.44Å; V5-R124 HydrophobicContact CG1-CG 4.49Å; V5-W131 CarbonylContact C-O 3.52Å; V5-W131 WeakPolarHBondContact CA-O 3.44Å; V5-W131 HydrophobicContact CG1-CB 4.45Å; V5-W131 HydrophobicContact CG2-CB 4.32Å; V5-E133 HydrophobicContact CG1-CB 3.71Å
6Q94.9Very high84.6Confident86 Ų8687.2 Ų87.240%0.40246%0.463SS..EExtended strand (participates in β ladder)trans-74.4146.7173.8-72.2-169.2-17.100110.3E130 W131 T132 E133Q6-E130 VanDerWaalsContact CD-OE2 3.28Å; Q6-E130 VanDerWaalsContact NE2-CD 3.32Å; Q6-E130 PolarHBondContact NE2-OE2 2.86Å; Q6-W131 PolarHBondContact N-O 2.91Å; Q6-T132 CarbonylContact O-C 3.59Å; Q6-T132 VanDerWaalsContact O-CA 3.31Å; Q6-T132 WeakPolarHBondContact O-CA 3.34Å; Q6-E133 PolarHBondContact O-N 2.88Å
7L96.4Very high85.3Confident60 Ų6083.6 Ų83.631%0.31444%0.442SS..EExtended strand (participates in β ladder)trans-100.1120.8177.5-57.5177.1000108.7K9 D10 K12 E133L7-K9 PolarHBondContact O-N 2.74Å; L7-D10 PolarHBondContact O-N 3.33Å; L7-K12 HydrophobicContact CD1-CD 4.43Å; L7-K12 HydrophobicContact CD1-CG 3.43Å; L7-K12 VanDerWaalsContact CD1-CG 3.43Å; L7-E133 HydrophobicContact CD2-CB 4.24Å
8F96.6Very high86Confident44 Ų4481 Ų8119%0.19344%0.439CS..G310 helixtrans-67.1123.9173.8-174-108.4000109.2D10 Q11 T132 E133 V134 K169 L170F8-D10 PolarHBondContact O-N 3.23Å; F8-Q11 PolarHBondContact O-N 3.38Å; F8-T132 HydrophobicContact CB-CG2 3.88Å; F8-E133 WeakPolarHBondContact CB-O 3.31Å; F8-E133 PolarHBondContact N-O 2.72Å; F8-V134 HydrophobicContact CB-CG2 4Å; F8-V134 HydrophobicContact CD1-CG1 4.32Å; F8-V134 HydrophobicContact CG-CG2 4.37Å; F8-K169 HydrophobicContact CD1-CD 4.44Å; F8-K169 HydrophobicContact CD1-CG 4.36Å; F8-K169 HydrophobicContact CE1-CD 4.24Å; F8-K169 HydrophobicContact CE1-CG 3.76Å; F8-L170 HydrophobicContact CD1-CD2 4.46Å; F8-L170 HydrophobicContact CD2-CD2 3.51Å; F8-L170 HydrophobicContact CE2-CD2 3.68Å; F8-L170 HydrophobicContact CG-CD2 3.93Å; F8-L170 HydrophobicContact CZ-CD2 4.22Å
9K95.8Very high86.6Confident113 Ų11381.1 Ų81.149%0.49144%0.436SS..G310 helixtrans56.329.9-179.1-57.5-65-159.2117.20113.6L7 Q11 E31L7-K9 PolarHBondContact O-N 2.74Å; K9-Q11 HydrophobicContact CB-CG 4.48Å; K9-Q11 PolarHBondContact O-N 3.26Å; K9-E31 HydrophobicContact CB-CB 4.48Å; K9-E31 HydrophobicContact CB-CG 3.72Å; K9-E31 VanDerWaalsContact CD-OE2 3.27Å; K9-E31 WeakPolarHBondContact CD-OE2 3.4Å; K9-E31 VanDerWaalsContact CE-OE2 3.27Å; K9-E31 WeakPolarHBondContact CE-OE2 3.08Å; K9-E31 HydrophobicContact CG-CB 4.3Å; K9-E31 HydrophobicContact CG-CG 3.96Å; K9-E31 VanDerWaalsContact CG-OE2 3.31Å; K9-E31 WeakPolarHBondContact CG-OE2 3.27Å; K9-E31 IonicContact NZ-OE2 2.55Å; K9-E31 PolarHBondContact NZ-OE2 3.22Å
10D96Very high87.1Confident142 Ų14277.1 Ų77.176%0.75942%0.415SS*.G310 helixtrans56.816.7-179.8-56.9-54.8000114.5L7 F8 K12L7-D10 PolarHBondContact O-N 3.33Å; F8-D10 PolarHBondContact O-N 3.23Å; D10-K12 PolarHBondContact O-N 3.09Å
11Q97.3Very high87.6Confident17 Ų1776.5 Ų76.58%0.07941%0.411CS..  trans-75.5124178-71.3-179.4-43.800110.5F8 K9 L16 D29 V135F8-Q11 PolarHBondContact O-N 3.38Å; K9-Q11 HydrophobicContact CB-CG 4.48Å; K9-Q11 PolarHBondContact O-N 3.26Å; Q11-L16 HydrophobicContact CB-CD1 3.86Å; Q11-L16 HydrophobicContact CG-CD1 4.16Å; Q11-D29 PolarHBondContact NE2-OD1 2.81Å; Q11-V135 HydrophobicContact CB-CB 4.28Å; Q11-V135 HydrophobicContact CB-CG2 4.11Å
12K96.8Very high90.8Very high92 Ų9272.5 Ų72.540%0.439%0.389SS..  trans-105111.2177.1-67.7171.3-179.6174.20110.3L7 D10 Q14 E15 L16L7-K12 HydrophobicContact CD1-CD 4.43Å; L7-K12 HydrophobicContact CD1-CG 3.43Å; L7-K12 VanDerWaalsContact CD1-CG 3.43Å; D10-K12 PolarHBondContact O-N 3.09Å; K12-Q14 PolarHBondContact O-N 3.49Å; K12-E15 HydrophobicContact CB-CB 4.13Å; K12-E15 HydrophobicContact CB-CG 4.24Å; K12-E15 HydrophobicContact CD-CG 4.15Å; K12-E15 WeakPolarHBondContact CD-OE1 3.15Å; K12-E15 VanDerWaalsContact CD-OE2 3.25Å; K12-E15 WeakPolarHBondContact CD-OE2 3.48Å; K12-E15 IonicContact NZ-OE1 3.56Å; K12-E15 PolarHBondContact NZ-OE1 3.3Å; K12-E15 IonicContact NZ-OE2 2.69Å; K12-E15 PolarHBondContact NZ-OE2 3.29Å; K12-E15 PolarHBondContact O-N 2.99Å; K12-L16 WeakPolarHBondContact O-CG 3.35Å; K12-L16 PolarHBondContact O-N 2.82Å
13Y96.9Very high93.7Very high3 Ų371.8 Ų71.81%0.01237%0.372CS..Hα-helixtrans-51.6-51.3-175.7170.2-113.9000113.5E15 L16 K17 I120 H122Y13-E15 PolarHBondContact O-N 2.8Å; Y13-L16 PolarHBondContact O-N 2.86Å; Y13-K17 HydrophobicContact CE1-CD 4.31Å; Y13-K17 HydrophobicContact CE2-CD 4.11Å; Y13-K17 VanDerWaalsContact O-CB 3.26Å; Y13-K17 WeakPolarHBondContact O-CB 3.2Å; Y13-K17 PolarHBondContact O-N 2.88Å; Y13-K17 WeakPolarHBondContact OH-CD 3.13Å; Y13-K17 PolarHBondContact OH-NZ 2.89Å; Y13-I120 HydrophobicContact CD2-CD1 4.15Å; Y13-I120 HydrophobicContact CD2-CG1 4.01Å; Y13-I120 HydrophobicContact CE2-CG1 4.1Å; Y13-I120 HydrophobicContact CE2-CG2 4.11Å; Y13-H122 AromaticContact CD1-CD2 3.51Å; Y13-H122 AromaticContact CD1-CE1 3.79Å; Y13-H122 AromaticContact CD1-CG 3.83Å; Y13-H122 AromaticContact CD1-ND1 3.98Å; Y13-H122 AromaticContact CD1-NE2 3.51Å; Y13-H122 HydrophobicContact CD2-CB 3.89Å; Y13-H122 AromaticContact CD2-CD2 3.88Å; Y13-H122 AromaticContact CD2-CG 3.96Å; Y13-H122 AromaticContact CE1-CD2 3.54Å; Y13-H122 AromaticContact CE1-NE2 3.51Å; Y13-H122 AromaticContact CE2-CD2 3.92Å; Y13-H122 HydrophobicContact CG-CB 3.92Å; Y13-H122 AromaticContact CG-CD2 3.68Å; Y13-H122 AromaticContact CG-CG 3.63Å; Y13-H122 AromaticContact CZ-CD2 3.75Å
14Q95.6Very high95.6Very high107 Ų10779.7 Ų79.750%0.539%0.391SS..Hα-helixtrans-67.1-38.5-174.9-65.6-66.5-1500113K12 G18K12-Q14 PolarHBondContact O-N 3.49Å; Q14-G18 PolarHBondContact O-N 3.03Å
15E97.1Very high96.4Very high104 Ų10480.6 Ų80.649%0.48638%0.379SS..Hα-helixtrans-68-46177.2-67.9-179.8-163.100110.8K12 Y13 G18 Q19K12-E15 HydrophobicContact CB-CB 4.13Å; K12-E15 HydrophobicContact CB-CG 4.24Å; K12-E15 HydrophobicContact CD-CG 4.15Å; K12-E15 WeakPolarHBondContact CD-OE1 3.15Å; K12-E15 VanDerWaalsContact CD-OE2 3.25Å; K12-E15 WeakPolarHBondContact CD-OE2 3.48Å; K12-E15 IonicContact NZ-OE1 3.56Å; K12-E15 PolarHBondContact NZ-OE1 3.3Å; K12-E15 IonicContact NZ-OE2 2.69Å; K12-E15 PolarHBondContact NZ-OE2 3.29Å; K12-E15 PolarHBondContact O-N 2.99Å; Y13-E15 PolarHBondContact O-N 2.8Å; E15-G18 PolarHBondContact O-N 2.78Å; E15-Q19 VanDerWaalsContact O-CG 3.29Å; E15-Q19 WeakPolarHBondContact O-CG 3.49Å; E15-Q19 PolarHBondContact O-N 3.33Å
16L97.9Very high96.8Very high36 Ų3681.3 Ų81.319%0.18838%0.381CS..Hα-helixtrans-63.5-44.4178.1-68.7171.6000111.8Q11 K12 Y13 Q19 C20 F27 I120 V135Q11-L16 HydrophobicContact CB-CD1 3.86Å; Q11-L16 HydrophobicContact CG-CD1 4.16Å; K12-L16 WeakPolarHBondContact O-CG 3.35Å; K12-L16 PolarHBondContact O-N 2.82Å; Y13-L16 PolarHBondContact O-N 2.86Å; L16-Q19 PolarHBondContact O-N 3.09Å; L16-C20 PolarHBondContact O-N 3.08Å; L16-C20 PolarHBondContact O-SG 3.03Å; L16-C20 VanDerWaalsContact O-SG 3.39Å; L16-F27 HydrophobicContact CB-CE2 4.42Å; L16-F27 HydrophobicContact CD1-CE2 4.1Å; L16-F27 HydrophobicContact CD1-CZ 4.09Å; L16-F27 HydrophobicContact CD2-CE2 4.21Å; L16-F27 HydrophobicContact CG-CE2 4.48Å; L16-I120 HydrophobicContact CB-CD1 3.62Å; L16-V135 HydrophobicContact CD1-CG1 4.28Å
17K97.2Very high96.9Very high26 Ų2677.6 Ų77.611%0.11336%0.364CS..Hα-helixtrans-60.8-46.3175.7-177171.3-176.3171.20111.3Y13 Q19 C20 I21 E106 K116 A118 I120Y13-K17 HydrophobicContact CE1-CD 4.31Å; Y13-K17 HydrophobicContact CE2-CD 4.11Å; Y13-K17 VanDerWaalsContact O-CB 3.26Å; Y13-K17 WeakPolarHBondContact O-CB 3.2Å; Y13-K17 PolarHBondContact O-N 2.88Å; Y13-K17 WeakPolarHBondContact OH-CD 3.13Å; Y13-K17 PolarHBondContact OH-NZ 2.89Å; K17-Q19 PolarHBondContact O-N 3.39Å; K17-C20 PolarHBondContact O-N 3.01Å; K17-I21 HydrophobicContact CG-CD1 3.9Å; K17-I21 VanDerWaalsContact O-CG1 3.3Å; K17-I21 WeakPolarHBondContact O-CG1 3.33Å; K17-I21 PolarHBondContact O-N 2.71Å; K17-E106 PolarHBondContact NZ-O 3.18Å; K17-K116 WeakPolarHBondContact CE-O 3.12Å; K17-A118 HydrophobicContact CG-CB 4.39Å; K17-I120 HydrophobicContact CB-CD1 4.48Å; K17-I120 HydrophobicContact CB-CG2 3.83Å; K17-I120 HydrophobicContact CD-CG2 4.2Å; K17-I120 HydrophobicContact CG-CG2 3.85Å
18G97.3Very high97Very high37 Ų3781.2 Ų81.238%0.38138%0.379SS..Hα-helixtrans-58.5-46.6177.200000112.6Q14 E15 C20 I21 E22Q14-G18 PolarHBondContact O-N 3.03Å; E15-G18 PolarHBondContact O-N 2.78Å; G18-C20 PolarHBondContact O-N 2.85Å; G18-I21 PolarHBondContact O-N 2.97Å; G18-E22 WeakPolarHBondContact O-CB 3.3Å; G18-E22 PolarHBondContact O-N 3.15Å
19Q97.6Very high97.1Very high83 Ų8379.3 Ų79.339%0.38837%0.37SS..Hα-helixtrans-61.4-43.7177.2-72.5172.88.400112.5E15 L16 K17 E22 Q23E15-Q19 VanDerWaalsContact O-CG 3.29Å; E15-Q19 WeakPolarHBondContact O-CG 3.49Å; E15-Q19 PolarHBondContact O-N 3.33Å; L16-Q19 PolarHBondContact O-N 3.09Å; K17-Q19 PolarHBondContact O-N 3.39Å; Q19-E22 PolarHBondContact O-N 3.3Å; Q19-Q23 VanDerWaalsContact O-CB 3.3Å; Q19-Q23 WeakPolarHBondContact O-CB 3.49Å; Q19-Q23 VanDerWaalsContact O-CG 3.28Å; Q19-Q23 WeakPolarHBondContact O-CG 3.4Å; Q19-Q23 PolarHBondContact O-N 2.53Å
20C97.8Very high97.1Very high1 Ų178.4 Ų78.41%0.00738%0.376CS..Hα-helixtrans-63.9-41.5178-73.80000112.1L16 K17 G18 Q23 R24 R25 A118L16-C20 PolarHBondContact O-N 3.08Å; L16-C20 PolarHBondContact O-SG 3.03Å; L16-C20 VanDerWaalsContact O-SG 3.39Å; K17-C20 PolarHBondContact O-N 3.01Å; G18-C20 PolarHBondContact O-N 2.85Å; C20-Q23 PolarHBondContact O-N 2.9Å; C20-R24 PolarHBondContact O-N 2.96Å; C20-R25 HydrophobicContact CB-CG 4.49Å; C20-R25 WeakPolarHBondContact CB-O 3.19Å; C20-R25 PolarHBondContact O-N 3.05Å; C20-A118 HydrophobicContact CB-CB 3.75Å
21I96.8Very high97.2Very high65 Ų6575.3 Ų75.333%0.33336%0.357SS..Hα-helixtrans-63-48.2175.7-68.1169.7000110.7K17 G18 Q23 R24 A118K17-I21 HydrophobicContact CG-CD1 3.9Å; K17-I21 VanDerWaalsContact O-CG1 3.3Å; K17-I21 WeakPolarHBondContact O-CG1 3.33Å; K17-I21 PolarHBondContact O-N 2.71Å; G18-I21 PolarHBondContact O-N 2.97Å; I21-Q23 VanDerWaalsContact C-N 3.32Å; I21-Q23 PolarHBondContact O-N 2.8Å; I21-R24 PolarHBondContact O-N 3.15Å; I21-R24 VanDerWaalsContact O-N 3.16Å; I21-A118 HydrophobicContact CG1-CB 4.01Å
22E97.2Very high97.3Very high159 Ų15974.8 Ų74.874%0.74336%0.355SS*.Hα-helixtrans-60-43.1179.5-175.9178.6-169.500111.8G18 Q19 R24G18-E22 WeakPolarHBondContact O-CB 3.3Å; G18-E22 PolarHBondContact O-N 3.15Å; Q19-E22 PolarHBondContact O-N 3.3Å; E22-R24 VanDerWaalsContact C-N 3.28Å; E22-R24 PolarHBondContact O-N 3.31Å
23Q96.8Very high97.3Very high112 Ų11273 Ų7352%0.52335%0.352SS..THydrogen-bonded Turntrans-82.8-1.8-179.6-65.4173.1-2.600113.5Q19 C20 I21 R25Q19-Q23 VanDerWaalsContact O-CB 3.3Å; Q19-Q23 WeakPolarHBondContact O-CB 3.49Å; Q19-Q23 VanDerWaalsContact O-CG 3.28Å; Q19-Q23 WeakPolarHBondContact O-CG 3.4Å; Q19-Q23 PolarHBondContact O-N 2.53Å; C20-Q23 PolarHBondContact O-N 2.9Å; I21-Q23 VanDerWaalsContact C-N 3.32Å; I21-Q23 PolarHBondContact O-N 2.8Å; Q23-R25 HydrophobicContact CB-CG 4.09Å; Q23-R25 PolarHBondContact O-N 2.97Å
24R95.3Very high97.3Very high236 Ų23675 Ų7589%0.89137%0.369SS*.THydrogen-bonded Turntrans51.341.1-176.6-57.7-177.7179-178.6-0.7113.4C20 I21 E22C20-R24 PolarHBondContact O-N 2.96Å; I21-R24 PolarHBondContact O-N 3.15Å; I21-R24 VanDerWaalsContact O-N 3.16Å; E22-R24 VanDerWaalsContact C-N 3.28Å; E22-R24 PolarHBondContact O-N 3.31Å
25R96.5Very high97.3Very high117 Ų11771.6 Ų71.644%0.44236%0.358SS..  trans-121.3157.2176.568.7178.1178.6121.2-0.8111C20 Q23C20-R25 HydrophobicContact CB-CG 4.49Å; C20-R25 WeakPolarHBondContact CB-O 3.19Å; C20-R25 PolarHBondContact O-N 3.05Å; Q23-R25 HydrophobicContact CB-CG 4.09Å; Q23-R25 PolarHBondContact O-N 2.97Å
26L97.9Very high97.2Very high67 Ų6771.4 Ų71.435%0.35136%0.36SS..  trans-83.6145.5169.5-58.7179.5000109.4Y117L26-Y117 HydrophobicContact CD1-CE1 4.4Å; L26-Y117 HydrophobicContact CD2-CD1 3.91Å; L26-Y117 HydrophobicContact CD2-CE1 3.47Å; L26-Y117 VanDerWaalsContact CD2-CE1 3.47Å
27F98.4Very high97.1Very high9 Ų976.3 Ų76.34%0.03938%0.382CS..  trans-66.4134.5175.2-175.7-119.2000109.7L16 D29 R53 A118 I120 V135 D137L16-F27 HydrophobicContact CB-CE2 4.42Å; L16-F27 HydrophobicContact CD1-CE2 4.1Å; L16-F27 HydrophobicContact CD1-CZ 4.09Å; L16-F27 HydrophobicContact CD2-CE2 4.21Å; L16-F27 HydrophobicContact CG-CE2 4.48Å; F27-D29 HydrophobicContact CE1-CB 3.77Å; F27-D29 HydrophobicContact CZ-CB 4.17Å; F27-R53 PolarHBondContact O-NH1 3.07Å; F27-R53 PolarHBondContact O-NH2 3.04Å; F27-A118 WeakPolarHBondContact CB-O 3.32Å; F27-A118 PolarHBondContact N-O 2.82Å; F27-I120 HydrophobicContact CB-CB 3.72Å; F27-I120 HydrophobicContact CB-CD1 4.29Å; F27-I120 HydrophobicContact CB-CG1 4.25Å; F27-I120 HydrophobicContact CD1-CB 3.89Å; F27-I120 HydrophobicContact CD1-CD1 3.77Å; F27-I120 HydrophobicContact CD1-CG1 3.56Å; F27-I120 HydrophobicContact CD2-CD1 4.12Å; F27-I120 HydrophobicContact CE1-CD1 4.1Å; F27-I120 HydrophobicContact CE1-CG1 4.09Å; F27-I120 HydrophobicContact CE2-CD1 4.42Å; F27-I120 HydrophobicContact CG-CB 4Å; F27-I120 HydrophobicContact CG-CD1 3.8Å; F27-I120 HydrophobicContact CG-CG1 3.95Å; F27-I120 HydrophobicContact CZ-CD1 4.42Å; F27-V135 HydrophobicContact CE1-CG1 3.89Å; F27-V135 HydrophobicContact CZ-CG1 4.27Å; F27-D137 HydrophobicContact CB-CB 4.49Å; F27-D137 HydrophobicContact CD1-CB 3.68Å; F27-D137 HydrophobicContact CE1-CB 4.36Å; F27-D137 HydrophobicContact CG-CB 4.44Å; F27-D137 WeakPolarHBondContact O-CB 3.42Å
28E98.1Very high97Very high135 Ų13575.2 Ų75.263%0.63138%0.378SS*.  trans-123.5123168.3-70178.4-169.500105.6P30E28-P30 WeakPolarHBondContact O-CD 3.31Å
29D98.2Very high97Very high4 Ų473.5 Ų73.52%0.02136%0.36CS..  trans-81.7109.1-168.4-171.8-1.1000111.2Q11 F27 E31 F32 D137 K169Q11-D29 PolarHBondContact NE2-OD1 2.81Å; F27-D29 HydrophobicContact CE1-CB 3.77Å; F27-D29 HydrophobicContact CZ-CB 4.17Å; D29-E31 PolarHBondContact O-N 3.32Å; D29-E31 PolarHBondContact OD1-N 3.47Å; D29-E31 VanDerWaalsContact OD1-N 3.17Å; D29-F32 CarbonylContact O-C 3.58Å; D29-F32 PolarHBondContact O-N 3.01Å; D29-D137 HydrophobicContact CB-CB 4.39Å; D29-D137 VanDerWaalsContact CB-OD2 3.29Å; D29-D137 WeakPolarHBondContact CB-OD2 3.48Å; D29-D137 PolarHBondContact N-OD2 3.29Å; D29-K169 IonicContact OD1-NZ 2.66Å; D29-K169 PolarHBondContact OD1-NZ 3.28Å; D29-K169 WeakPolarHBondContact OD2-CE 3.41Å; D29-K169 IonicContact OD2-NZ 3.77Å; D29-K169 PolarHBondContact OD2-NZ 2.82Å
30P97.3Very high96.8Very high95 Ų9571.5 Ų71.562%0.61735%0.35SS*.THydrogen-bonded Turntrans-69.4-21.4-17830.1-36.1000112.7E28E28-P30 WeakPolarHBondContact O-CD 3.31Å
31E97.6Very high96.5Very high77 Ų7774.5 Ų74.536%0.3636%0.362SS..THydrogen-bonded Turntrans-90.2-7.6-178.7-65.8-66.1140.700112.7K9 D29K9-E31 HydrophobicContact CB-CB 4.48Å; K9-E31 HydrophobicContact CB-CG 3.72Å; K9-E31 VanDerWaalsContact CD-OE2 3.27Å; K9-E31 WeakPolarHBondContact CD-OE2 3.4Å; K9-E31 VanDerWaalsContact CE-OE2 3.27Å; K9-E31 WeakPolarHBondContact CE-OE2 3.08Å; K9-E31 HydrophobicContact CG-CB 4.3Å; K9-E31 HydrophobicContact CG-CG 3.96Å; K9-E31 VanDerWaalsContact CG-OE2 3.31Å; K9-E31 WeakPolarHBondContact CG-OE2 3.27Å; K9-E31 IonicContact NZ-OE2 2.55Å; K9-E31 PolarHBondContact NZ-OE2 3.22Å; D29-E31 PolarHBondContact O-N 3.32Å; D29-E31 PolarHBondContact OD1-N 3.47Å; D29-E31 VanDerWaalsContact OD1-N 3.17Å
32F98Very high96.2Very high5 Ų576.7 Ų76.72%0.02238%0.378CS..SBendtrans-151.469.5176.7-159.6-109.2000110.7D29 S38 W51 K165 A168 K169 Y174D29-F32 CarbonylContact O-C 3.58Å; D29-F32 PolarHBondContact O-N 3.01Å; F32-S38 WeakPolarHBondContact CD2-OG 3.38Å; F32-S38 WeakPolarHBondContact CE2-OG 3.27Å; F32-S38 WeakPolarHBondContact CZ-O 3.25Å; F32-W51 HydrophobicContact CE1-CH2 4.46Å; F32-K165 HydrophobicContact CD1-CG 4.32Å; F32-K165 HydrophobicContact CE1-CG 4.13Å; F32-A168 HydrophobicContact CZ-CB 4.05Å; F32-K169 HydrophobicContact CB-CB 4.16Å; F32-K169 HydrophobicContact CB-CD 3.66Å; F32-K169 HydrophobicContact CB-CG 3.8Å; F32-K169 HydrophobicContact CD1-CB 4.15Å; F32-K169 HydrophobicContact CD2-CB 3.76Å; F32-K169 HydrophobicContact CD2-CG 3.95Å; F32-K169 HydrophobicContact CE1-CB 4.48Å; F32-K169 HydrophobicContact CE2-CB 4.14Å; F32-K169 HydrophobicContact CG-CB 3.75Å; F32-K169 HydrophobicContact CG-CD 4.21Å; F32-K169 HydrophobicContact CG-CG 3.92Å; F32-K169 HydrophobicContact CZ-CB 4.48Å; F32-Y174 HydrophobicContact CE1-CD2 4.34Å; F32-Y174 HydrophobicContact CE1-CE2 4.01Å; F32-Y174 HydrophobicContact CZ-CD2 4.18Å; F32-Y174 HydrophobicContact CZ-CE2 4.3Å
33P97.6Very high95.5Very high54 Ų5479 Ų7935%0.35138%0.38SS..  trans-66.8149.3-169.827.3-35.1000112.4S35 S38P33-S35 PolarHBondContact O-N 2.88Å; P33-S35 PolarHBondContact O-OG 3Å; P33-S38 VanDerWaalsContact O-CB 3.28Å; P33-S38 WeakPolarHBondContact O-CB 3.46Å; P33-S38 PolarHBondContact O-OG 3.31Å
34A97.5Very high95Very high45 Ų4576.4 Ų76.437%0.37238%0.378SS..SBendtrans-67.870.1173.600000112.2W51 L139A34-W51 HydrophobicContact CB-CB 3.88Å; A34-W51 HydrophobicContact CB-CD2 3.58Å; A34-W51 HydrophobicContact CB-CE3 3.97Å; A34-W51 HydrophobicContact CB-CG 3.55Å; A34-L139 HydrophobicContact CB-CD1 3.96Å
35S95.9Very high94.6Very high37 Ų3766.5 Ų66.526%0.25934%0.344SS..SBendtrans-145.9170-171.2720000111.5P33 E37 S38P33-S35 PolarHBondContact O-N 2.88Å; P33-S35 PolarHBondContact O-OG 3Å; S35-E37 PolarHBondContact O-N 3.37Å; S35-S38 PolarHBondContact O-N 2.67Å
36D94.9Very high93.9Very high99 Ų9966.3 Ų66.353%0.52936%0.358SS..Hα-helixtrans-59.9-31.3178.5-71.4-10.6000112.6S38 L39 F40D36-S38 PolarHBondContact O-N 2.75Å; D36-L39 PolarHBondContact O-N 3.21Å; D36-F40 HydrophobicContact CB-CE1 3.71Å; D36-F40 HydrophobicContact CB-CZ 3.71Å; D36-F40 PolarHBondContact O-N 2.97Å; D36-F40 VanDerWaalsContact O-O 3.1Å
37E94.3Very high93.4Very high139 Ų13970.9 Ų70.965%0.6537%0.371SS*.Hα-helixtrans-63.4-30-179.9-60.3-170.116600113.2S35 L39S35-E37 PolarHBondContact O-N 3.37Å; E37-L39 VanDerWaalsContact C-N 3.34Å
38S96.9Very high93Very high4 Ų480.8 Ų80.83%0.02841%0.408CS..Hα-helixtrans-79.7-18.2174.7-77.90000112.7F32 P33 S35 D36 S173 Y174F32-S38 WeakPolarHBondContact CD2-OG 3.38Å; F32-S38 WeakPolarHBondContact CE2-OG 3.27Å; F32-S38 WeakPolarHBondContact CZ-O 3.25Å; P33-S38 VanDerWaalsContact O-CB 3.28Å; P33-S38 WeakPolarHBondContact O-CB 3.46Å; P33-S38 PolarHBondContact O-OG 3.31Å; S35-S38 PolarHBondContact O-N 2.67Å; D36-S38 PolarHBondContact O-N 2.75Å; S38-S173 CarbonylContact O-C 3.52Å; S38-S173 VanDerWaalsContact O-CA 3.27Å; S38-S173 WeakPolarHBondContact O-CA 3.45Å; S38-S173 WeakPolarHBondContact O-CB 3.44Å; S38-Y174 WeakPolarHBondContact O-CD2 3.41Å; S38-Y174 PolarHBondContact O-N 3.34Å
39L95.6Very high92.9Very high1 Ų175.3 Ų75.31%0.00538%0.384CS..Hα-helixtrans-92.5-52.7-178.3-63174.5000111.5D36 E37 V49 W51 P141 Y149 Y174 E175D36-L39 PolarHBondContact O-N 3.21Å; E37-L39 VanDerWaalsContact C-N 3.34Å; L39-V49 HydrophobicContact CD1-CB 3.84Å; L39-V49 HydrophobicContact CD1-CG1 3.78Å; L39-V49 HydrophobicContact CD1-CG2 4.03Å; L39-W51 HydrophobicContact CD1-CZ2 4.33Å; L39-W51 HydrophobicContact CD2-CH2 4.16Å; L39-W51 HydrophobicContact CD2-CZ2 3.62Å; L39-W51 HydrophobicContact CG-CZ2 3.79Å; L39-P141 HydrophobicContact CD2-CB 3.87Å; L39-P141 HydrophobicContact CD2-CG 3.61Å; L39-Y149 HydrophobicContact CD2-CE2 3.85Å; L39-Y174 HydrophobicContact CD2-CD2 4.04Å; L39-E175 WeakPolarHBondContact O-CB 3.31Å; L39-E175 PolarHBondContact O-N 2.82Å
40F94Very high92.9Very high41 Ų4179.2 Ų79.218%0.1840%0.402CS..  trans-152.2160.2-170.564.2-87.4000112.7D36 R43 A44 P45 E175D36-F40 HydrophobicContact CB-CE1 3.71Å; D36-F40 HydrophobicContact CB-CZ 3.71Å; D36-F40 PolarHBondContact O-N 2.97Å; D36-F40 VanDerWaalsContact O-O 3.1Å; F40-R43 VanDerWaalsContact CB-O 3.3Å; F40-R43 WeakPolarHBondContact CB-O 3.46Å; F40-R43 WeakPolarHBondContact CG-O 3.42Å; F40-A44 HydrophobicContact CD2-CB 4.25Å; F40-A44 HydrophobicContact CE1-CB 4.18Å; F40-A44 HydrophobicContact CE2-CB 3.71Å; F40-A44 HydrophobicContact CZ-CB 3.67Å; F40-P45 HydrophobicContact CD1-CG 4.22Å; F40-P45 VanDerWaalsContact CE1-CD 3.43Å; F40-P45 HydrophobicContact CE1-CG 4.43Å; F40-E175 VanDerWaalsContact CA-OE2 3.22Å; F40-E175 WeakPolarHBondContact CA-OE2 3.22Å; F40-E175 HydrophobicContact CB-CB 4.24Å; F40-E175 VanDerWaalsContact CB-OE2 3.27Å; F40-E175 WeakPolarHBondContact CB-OE2 3.29Å
41Y92Very high92.9Very high63 Ų6376.6 Ų76.625%0.24738%0.379CS..SBendtrans-132.6-13.217254-90.5000112.5S173 E175 A176 K414 K415Y41-S173 WeakPolarHBondContact CD1-OG 3.33Å; Y41-S173 WeakPolarHBondContact CE1-OG 3.42Å; Y41-E175 HydrophobicContact CD1-CB 4.28Å; Y41-E175 HydrophobicContact CE1-CB 3.84Å; Y41-E175 HydrophobicContact CE1-CG 3.94Å; Y41-E175 PolarHBondContact N-OE2 3.4Å; Y41-A176 HydrophobicContact CE1-CB 4.39Å; Y41-K414 HydrophobicContact CE2-CB 4.44Å; Y41-K414 WeakPolarHBondContact OH-CB 3.39Å; Y41-K415 HydrophobicContact CD1-CB 4.23Å; Y41-K415 HydrophobicContact CD2-CB 4Å; Y41-K415 HydrophobicContact CD2-CG 4.28Å; Y41-K415 HydrophobicContact CG-CB 3.86Å; Y41-K415 HydrophobicContact CG-CD 4.47Å; Y41-K415 HydrophobicContact CG-CG 4.01Å
42T89.7Confident92.9Very high111 Ų11175.2 Ų75.268%0.68137%0.372SS*.SBendtrans-121-54.2172.739.90000113.6E175T42-E175 PolarHBondContact N-OE2 2.91Å; T42-E175 PolarHBondContact OG1-OE1 3.16Å; T42-E175 PolarHBondContact OG1-OE2 3.38Å
43R82.9Confident92.9Very high208 Ų20875.8 Ų75.879%0.78537%0.374SS*.  trans-113.9111.1-172.4-172.2177.8-179.6-179.30112.1F40 E175F40-R43 VanDerWaalsContact CB-O 3.3Å; F40-R43 WeakPolarHBondContact CB-O 3.46Å; F40-R43 WeakPolarHBondContact CG-O 3.42Å; R43-E175 WeakPolarHBondContact CB-OE1 3.36Å; R43-E175 PolarHBondContact N-OE1 3.28Å
44A87.2Confident92.9Very high58 Ų5873.2 Ų73.248%0.47936%0.358SS..  trans-64.2143.6172.300000111.6F40F40-A44 HydrophobicContact CD2-CB 4.25Å; F40-A44 HydrophobicContact CE1-CB 4.18Å; F40-A44 HydrophobicContact CE2-CB 3.71Å; F40-A44 HydrophobicContact CZ-CB 3.67Å
45P85.5Confident92.8Very high27 Ų2776 Ų7618%0.17536%0.361CS..  trans-55.7154.1169.8-26.735000112.3F40 R47 V49F40-P45 HydrophobicContact CD1-CG 4.22Å; F40-P45 VanDerWaalsContact CE1-CD 3.43Å; F40-P45 HydrophobicContact CE1-CG 4.43Å; P45-R47 PolarHBondContact O-N 2.77Å; P45-R47 VanDerWaalsContact O-N 3.17Å; P45-V49 HydrophobicContact CB-CG2 3.84Å; P45-V49 HydrophobicContact CG-CG2 3.75Å
46P81.9Confident92.9Very high114 Ų11479.9 Ų79.974%0.7438%0.376SS*.SBendtrans-67.7-17.6-17427.8-35.9000114.1M143P46-M143 HydrophobicContact CG-CE 4.4Å; P46-M143 HydrophobicContact CG-SD 4.36Å
47R87.8Confident92.9Very high163 Ų16377.6 Ų77.662%0.61536%0.363SS*.SBendtrans-138.4166.6176.3-58.1-178.6177.5-178.9-2.3109.6P45 V49 M143 D144P45-R47 PolarHBondContact O-N 2.77Å; P45-R47 VanDerWaalsContact O-N 3.17Å; R47-V49 PolarHBondContact O-N 3.27Å; R47-M143 HydrophobicContact CB-CG 4.4Å; R47-M143 HydrophobicContact CB-SD 3.72Å; R47-M143 HydrophobicContact CG-SD 4.44Å; R47-D144 IonicContact CZ-OD2 3.67Å; R47-D144 IonicContact NH1-OD2 3.84Å; R47-D144 PolarHBondContact NH1-OD2 2.87Å
48R90.8Very high92.9Very high216 Ų21672.3 Ų72.382%0.81534%0.341SS*.  trans-59.6128.3175.4-173.8179.7-177-165.80.3110
49V96Very high92.7Very high21 Ų2181.7 Ų81.713%0.12738%0.384CS..  trans-88.9134175.2176.90000109.7L39 P45 R47 P141 T142 M143 I148L39-V49 HydrophobicContact CD1-CB 3.84Å; L39-V49 HydrophobicContact CD1-CG1 3.78Å; L39-V49 HydrophobicContact CD1-CG2 4.03Å; P45-V49 HydrophobicContact CB-CG2 3.84Å; P45-V49 HydrophobicContact CG-CG2 3.75Å; R47-V49 PolarHBondContact O-N 3.27Å; V49-P141 HydrophobicContact CG1-CB 3.81Å; V49-T142 WeakPolarHBondContact CA-O 3.45Å; V49-M143 HydrophobicContact CG2-CG 4.28Å; V49-I148 HydrophobicContact CG1-CD1 4.29Å; V49-I148 HydrophobicContact CG2-CD1 3.81Å
50E96.9Very high92.6Very high85 Ų8585.7 Ų85.740%0.39741%0.406SS..EExtended strand (participates in β ladder)trans-110.7129.8171.2-65179.4173.200108.7K52 T142E50-K52 WeakPolarHBondContact OE2-CE 3.24Å; E50-K52 IonicContact OE2-NZ 3.19Å; E50-K52 PolarHBondContact OE2-NZ 3.42Å; E50-T142 PolarHBondContact N-O 3.43Å; E50-T142 WeakPolarHBondContact O-CA 3.46Å; E50-T142 WeakPolarHBondContact O-CB 3.5Å; E50-T142 PolarHBondContact O-N 3.04Å; E50-T142 PolarHBondContact O-OG1 3.46Å
51W98.1Very high92.7Very high40 Ų4084 Ų8415%0.15240%0.399CS..EExtended strand (participates in β ladder)trans-88.4120.1174.8-7083.8000109.2F32 A34 L39 L139 L140 P141 Y174F32-W51 HydrophobicContact CE1-CH2 4.46Å; A34-W51 HydrophobicContact CB-CB 3.88Å; A34-W51 HydrophobicContact CB-CD2 3.58Å; A34-W51 HydrophobicContact CB-CE3 3.97Å; A34-W51 HydrophobicContact CB-CG 3.55Å; L39-W51 HydrophobicContact CD1-CZ2 4.33Å; L39-W51 HydrophobicContact CD2-CH2 4.16Å; L39-W51 HydrophobicContact CD2-CZ2 3.62Å; L39-W51 HydrophobicContact CG-CZ2 3.79Å; W51-L139 HydrophobicContact CB-CB 4.31Å; W51-L139 HydrophobicContact CB-CD2 4.39Å; W51-L139 HydrophobicContact CE3-CB 3.95Å; W51-L139 VanDerWaalsContact CE3-O 3.26Å; W51-L139 WeakPolarHBondContact CZ3-O 3.15Å; W51-L140 WeakPolarHBondContact CA-O 3.35Å; W51-P141 HydrophobicContact CD2-CG 4.36Å; W51-P141 HydrophobicContact CE3-CG 4.02Å; W51-P141 HydrophobicContact CH2-CG 3.79Å; W51-P141 HydrophobicContact CZ2-CG 4.12Å; W51-P141 HydrophobicContact CZ3-CG 3.73Å; W51-Y174 HydrophobicContact CH2-CE2 4.2Å
52K98.2Very high92.8Very high48 Ų4883 Ų8321%0.20940%0.396CS..EExtended strand (participates in β ladder)trans-130.2142.6-177.5-68.5-172.2-179.6169.90110.8E50 E56 L57 L140 T142E50-K52 WeakPolarHBondContact OE2-CE 3.24Å; E50-K52 IonicContact OE2-NZ 3.19Å; E50-K52 PolarHBondContact OE2-NZ 3.42Å; K52-E56 HydrophobicContact CB-CB 4.27Å; K52-L57 HydrophobicContact CB-CD1 4.48Å; K52-L57 HydrophobicContact CB-CD2 3.92Å; K52-L57 HydrophobicContact CB-CG 4.14Å; K52-L57 HydrophobicContact CD-CD2 3.86Å; K52-L57 HydrophobicContact CG-CD2 4.5Å; K52-L140 PolarHBondContact N-O 2.86Å; K52-L140 PolarHBondContact O-N 2.86Å; K52-T142 HydrophobicContact CB-CG2 4.23Å
53R98.1Very high93Very high17 Ų1777.7 Ų77.76%0.06436%0.364CS..  trans-79.9156.4172.3-59.3-173.1-176.6-99.81.3110.6F27 K55 E56 L57 G119 D138 L139F27-R53 PolarHBondContact O-NH1 3.07Å; F27-R53 PolarHBondContact O-NH2 3.04Å; R53-K55 PolarHBondContact O-N 3.14Å; R53-K55 VanDerWaalsContact O-N 3.14Å; R53-E56 WeakPolarHBondContact CB-OE2 3.5Å; R53-E56 PolarHBondContact N-OE2 3.07Å; R53-E56 WeakPolarHBondContact O-CB 3.33Å; R53-E56 PolarHBondContact O-N 3.23Å; R53-L57 PolarHBondContact O-N 2.76Å; R53-G119 PolarHBondContact NH1-O 2.85Å; R53-D138 WeakPolarHBondContact CA-O 3.23Å; R53-D138 VanDerWaalsContact CD-OD1 3.26Å; R53-D138 WeakPolarHBondContact CD-OD1 3.48Å; R53-D138 WeakPolarHBondContact CG-OD1 3.4Å; R53-D138 IonicContact CZ-OD1 2.82Å; R53-D138 IonicContact NE-OD1 2.8Å; R53-D138 IonicContact NH1-OD1 2.94Å; R53-D138 PolarHBondContact NH1-OD1 2.83Å; R53-L139 HydrophobicContact CG-CD2 3.6Å; R53-L139 HydrophobicContact CG-CG 4.06Å
54P97.4Very high93.4Very high0 Ų068.9 Ų68.90%033%0.331CS..Hα-helixtrans-49.4-39.4175.9-35.339.6000114.8E56 L57 C58 P61 W109 D138 L140 F158P54-E56 PolarHBondContact O-N 3.32Å; P54-L57 PolarHBondContact O-N 3.29Å; P54-C58 PolarHBondContact O-N 3.16Å; P54-P61 HydrophobicContact CB-CB 3.56Å; P54-P61 HydrophobicContact CB-CG 4.22Å; P54-W109 HydrophobicContact CB-CH2 4.17Å; P54-W109 HydrophobicContact CB-CZ2 3.8Å; P54-W109 HydrophobicContact CG-CH2 3.85Å; P54-W109 HydrophobicContact CG-CZ2 3.66Å; P54-D138 WeakPolarHBondContact CD-O 3.36Å; P54-D138 HydrophobicContact CG-CB 4.34Å; P54-L140 HydrophobicContact CG-CD1 4.34Å; P54-F158 HydrophobicContact CB-CD1 4.05Å; P54-F158 HydrophobicContact CB-CD2 3.79Å; P54-F158 HydrophobicContact CB-CE1 3.97Å; P54-F158 HydrophobicContact CB-CE2 3.72Å; P54-F158 HydrophobicContact CB-CG 3.96Å; P54-F158 HydrophobicContact CB-CZ 3.81Å; P54-F158 HydrophobicContact CG-CB 4.34Å; P54-F158 HydrophobicContact CG-CD1 3.8Å; P54-F158 HydrophobicContact CG-CD2 4.18Å; P54-F158 HydrophobicContact CG-CE1 4.12Å; P54-F158 HydrophobicContact CG-CE2 4.47Å; P54-F158 HydrophobicContact CG-CG 3.83Å; P54-F158 HydrophobicContact CG-CZ 4.45Å
55K95.6Very high93.5Very high104 Ų10467.8 Ų67.845%0.45232%0.318SS..Hα-helixtrans-65.1-18.3176.7-71.6-174.2175.2179.30114.6R53 P61 Y117R53-K55 PolarHBondContact O-N 3.14Å; R53-K55 VanDerWaalsContact O-N 3.14Å; K55-P61 HydrophobicContact CG-CG 3.74Å; K55-Y117 HydrophobicContact CD-CE1 4.08Å
56E96.8Very high93.4Very high119 Ų11974.7 Ų74.756%0.55635%0.354SS*.Hα-helixtrans-89.6-12.3174.2-59.7172.77900112K52 R53 P54K52-E56 HydrophobicContact CB-CB 4.27Å; R53-E56 WeakPolarHBondContact CB-OE2 3.5Å; R53-E56 PolarHBondContact N-OE2 3.07Å; R53-E56 WeakPolarHBondContact O-CB 3.33Å; R53-E56 PolarHBondContact O-N 3.23Å; P54-E56 PolarHBondContact O-N 3.32Å
57L95.8Very high93.4Very high51 Ų5171 Ų7127%0.26734%0.336SS..Hα-helixtrans-104.2-31.1-177-59.9176000112.5K52 R53 P54 T142 L147 F158K52-L57 HydrophobicContact CB-CD1 4.48Å; K52-L57 HydrophobicContact CB-CD2 3.92Å; K52-L57 HydrophobicContact CB-CG 4.14Å; K52-L57 HydrophobicContact CD-CD2 3.86Å; K52-L57 HydrophobicContact CG-CD2 4.5Å; R53-L57 PolarHBondContact O-N 2.76Å; P54-L57 PolarHBondContact O-N 3.29Å; L57-T142 HydrophobicContact CD1-CG2 4.1Å; L57-T142 HydrophobicContact CD2-CG2 4.03Å; L57-L147 HydrophobicContact CD1-CD2 4.01Å; L57-L147 HydrophobicContact CD1-CG 4.35Å; L57-F158 HydrophobicContact CB-CZ 4.49Å; L57-F158 HydrophobicContact CD1-CE1 4.17Å
58C94.4Very high93.1Very high27 Ų2764.6 Ų64.618%0.18231%0.314CS..  trans-149.6158.5175.868.60000112.2P54 N156 F158P54-C58 PolarHBondContact O-N 3.16Å; C58-N156 HydrophobicContact CB-CB 4.36Å; C58-F158 VanDerWaalsContact SG-CE2 3.55Å
59E91.5Very high92.8Very high202 Ų20256.2 Ų56.294%0.94429%0.289SS*.SBendtrans-71-34.5-177.2-63.8-175.3166.700113.9
60D94.2Very high92Very high84 Ų8455.7 Ų55.745%0.44929%0.286SS..SBendtrans-13070.9-172.2-176.440.4000111.2H62 N156D60-H62 PolarHBondContact O-CD2 3.43Å; D60-H62 IonicContact OD1-CE1 2.76Å; D60-H62 IonicContact OD1-NE2 2.63Å; D60-H62 PolarHBondContact OD1-NE2 2.78Å; D60-H62 IonicContact OD2-CD2 3.3Å; D60-H62 IonicContact OD2-CE1 2.57Å; D60-H62 IonicContact OD2-NE2 2.97Å; D60-H62 PolarHBondContact OD2-NE2 2.89Å; D60-N156 VanDerWaalsContact O-CB 3.25Å; D60-N156 WeakPolarHBondContact O-CB 3.33Å; D60-N156 PolarHBondContact O-ND2 2.96Å
61P95.7Very high91.2Very high6 Ų654.6 Ų54.64%0.03928%0.281CS..  trans-71.3138.1-178.629.7-34.2000111.6P54 K55 W109 F158P54-P61 HydrophobicContact CB-CB 3.56Å; P54-P61 HydrophobicContact CB-CG 4.22Å; K55-P61 HydrophobicContact CG-CG 3.74Å; P61-W109 HydrophobicContact CB-CD2 4.21Å; P61-W109 HydrophobicContact CB-CZ2 4.46Å; P61-W109 HydrophobicContact CG-CD2 4.23Å; P61-W109 HydrophobicContact CG-CG 4.18Å; P61-W109 VanDerWaalsContact O-CB 3.26Å; P61-W109 WeakPolarHBondContact O-CB 3.49Å; P61-F158 HydrophobicContact CB-CD2 3.99Å; P61-F158 HydrophobicContact CB-CE2 3.71Å
62H95.3Very high90.4Very high42 Ų4253.2 Ų53.219%0.19428%0.276CS..BIsolated β-bridgetrans-126.2151173.2-66.1-88.4000110.2D60 V65 E108 W109 N156 E157 F158D60-H62 PolarHBondContact O-CD2 3.43Å; D60-H62 IonicContact OD1-CE1 2.76Å; D60-H62 IonicContact OD1-NE2 2.63Å; D60-H62 PolarHBondContact OD1-NE2 2.78Å; D60-H62 IonicContact OD2-CD2 3.3Å; D60-H62 IonicContact OD2-CE1 2.57Å; D60-H62 IonicContact OD2-NE2 2.97Å; D60-H62 PolarHBondContact OD2-NE2 2.89Å; H62-V65 HydrophobicContact CB-CG2 3.91Å; H62-E108 WeakPolarHBondContact CA-OE1 3.02Å; H62-W109 VanDerWaalsContact C-CE3 3.43Å; H62-W109 VanDerWaalsContact C-CZ3 3.41Å; H62-N156 PolarHBondContact CD2-ND2 3.39Å; H62-N156 PolarHBondContact N-O 3.38Å; H62-E157 WeakPolarHBondContact O-CA 3.29Å; H62-F158 PolarHBondContact O-N 2.87Å
63L93Very high89.8Confident0 Ų051 Ų510%027%0.266CS..SBendtrans-72.3-44.9169.1-165.260.4000107.9Q107 E108 W109 F121 W159 L162L63-Q107 HydrophobicContact CD2-CB 3.81Å; L63-E108 WeakPolarHBondContact CB-OE2 3.49Å; L63-E108 VanDerWaalsContact N-CD 3.34Å; L63-E108 PolarHBondContact N-OE1 3.05Å; L63-E108 PolarHBondContact N-OE2 3.47Å; L63-W109 HydrophobicContact CB-CE3 4.23Å; L63-W109 HydrophobicContact CB-CZ3 3.94Å; L63-W109 HydrophobicContact CD1-CZ3 4.22Å; L63-W109 VanDerWaalsContact N-CE3 3.31Å; L63-W109 VanDerWaalsContact N-CZ3 3.31Å; L63-F121 HydrophobicContact CD1-CD1 4.05Å; L63-F121 HydrophobicContact CD1-CE1 3.91Å; L63-F121 HydrophobicContact CD2-CD1 4.26Å; L63-F121 HydrophobicContact CD2-CE1 4.2Å; L63-W159 HydrophobicContact CD1-CB 3.95Å; L63-W159 HydrophobicContact CG-CB 4.11Å; L63-W159 WeakPolarHBondContact O-CB 3.32Å; L63-W159 VanDerWaalsContact O-CD1 3.23Å; L63-W159 PolarHBondContact O-N 2.9Å; L63-W159 VanDerWaalsContact O-N 3.13Å; L63-L162 HydrophobicContact CD1-CD1 3.76Å
64F91.4Very high89.2Confident22 Ų2250.8 Ų50.810%0.09627%0.266CS..  trans-130.5138.7178-53.3-77.8000112.8I68 W97 I101 F104 E108 W159F64-I68 HydrophobicContact CD1-CD1 3.99Å; F64-I68 HydrophobicContact CD1-CG1 3.38Å; F64-I68 HydrophobicContact CE1-CD1 3.36Å; F64-I68 HydrophobicContact CE1-CG1 3.32Å; F64-I68 HydrophobicContact CZ-CD1 4.18Å; F64-I68 HydrophobicContact CZ-CG1 4.44Å; F64-W97 HydrophobicContact CE1-CZ3 4.45Å; F64-W97 HydrophobicContact CZ-CZ3 4.05Å; F64-I101 HydrophobicContact CE1-CD1 3.97Å; F64-I101 HydrophobicContact CZ-CD1 3.74Å; F64-I101 HydrophobicContact CZ-CG2 4.1Å; F64-F104 HydrophobicContact CD2-CD2 4.12Å; F64-F104 HydrophobicContact CE2-CB 3.78Å; F64-F104 AromaticContact CE2-CD2 3.91Å; F64-F104 HydrophobicContact CE2-CD2 3.91Å; F64-F104 HydrophobicContact CE2-CG 4.23Å; F64-F104 HydrophobicContact CZ-CB 4.29Å; F64-E108 PolarHBondContact N-OE2 2.94Å; F64-E108 VanDerWaalsContact N-OE2 3.17Å; F64-W159 HydrophobicContact CD1-CB 3.95Å; F64-W159 AromaticContact CD1-CD1 3.54Å; F64-W159 HydrophobicContact CD1-CD2 4.5Å; F64-W159 AromaticContact CD1-CG 3.73Å; F64-W159 HydrophobicContact CD1-CG 3.73Å; F64-W159 HydrophobicContact CE1-CB 3.44Å; F64-W159 VanDerWaalsContact CE1-CB 3.44Å; F64-W159 AromaticContact CE1-CD1 3.79Å; F64-W159 HydrophobicContact CE1-CD2 4.05Å; F64-W159 AromaticContact CE1-CG 3.47Å; F64-W159 HydrophobicContact CE1-CG 3.47Å; F64-W159 VanDerWaalsContact CE1-CG 3.47Å; F64-W159 HydrophobicContact CZ-CB 3.93Å; F64-W159 HydrophobicContact CZ-CG 4.42Å
65V88.8Confident88.7Confident35 Ų3552 Ų5221%0.21227%0.272CS..SBendtrans-118108.9172-179.90000109.2H62 G67 V154 E157H62-V65 HydrophobicContact CB-CG2 3.91Å; V65-G67 VanDerWaalsContact C-N 3.29Å; V65-G67 PolarHBondContact O-N 2.86Å; V65-V154 HydrophobicContact CB-CG1 4Å; V65-V154 HydrophobicContact CG1-CG1 4.01Å; V65-V154 HydrophobicContact CG2-CG1 3.95Å; V65-E157 HydrophobicContact CB-CB 4.36Å; V65-E157 HydrophobicContact CG2-CB 3.86Å; V65-E157 HydrophobicContact CG2-CG 4.31Å; V65-E157 PolarHBondContact N-OE1 2.94Å
66N83.1Confident88.5Confident173 Ų17348 Ų4893%0.92526%0.26SS*.SBendtrans64.225.7-175.2-53.2-53.5000115.1
67G82.8Confident88.1Confident35 Ų3546.9 Ų46.936%0.36126%0.257SS..SBendtrans101-157178.300000112V65V65-G67 VanDerWaalsContact C-N 3.29Å; V65-G67 PolarHBondContact O-N 2.86Å
68I81.9Confident87.7Confident29 Ų2945.3 Ų45.315%0.14925%0.249CC..  trans-106.4130.7173.1-68.7-173.6000108.6F64 A91 W97 I101 W159F64-I68 HydrophobicContact CD1-CD1 3.99Å; F64-I68 HydrophobicContact CD1-CG1 3.38Å; F64-I68 HydrophobicContact CE1-CD1 3.36Å; F64-I68 HydrophobicContact CE1-CG1 3.32Å; F64-I68 HydrophobicContact CZ-CD1 4.18Å; F64-I68 HydrophobicContact CZ-CG1 4.44Å; I68-A91 HydrophobicContact CG2-CB 3.55Å; I68-W97 HydrophobicContact CD1-CB 4.16Å; I68-W97 HydrophobicContact CD1-CD2 3.27Å; I68-W97 HydrophobicContact CD1-CE3 3.34Å; I68-W97 HydrophobicContact CD1-CG 3.64Å; I68-W97 HydrophobicContact CD1-CH2 4.21Å; I68-W97 HydrophobicContact CD1-CZ2 4.16Å; I68-W97 HydrophobicContact CD1-CZ3 3.82Å; I68-W97 HydrophobicContact CG1-CD2 4.29Å; I68-W97 HydrophobicContact CG1-CE3 4.49Å; I68-W97 HydrophobicContact CG1-CZ2 4.42Å; I68-I101 HydrophobicContact CD1-CD1 4.19Å; I68-W159 HydrophobicContact CD1-CD2 4.5Å; I68-W159 HydrophobicContact CG2-CH2 3.9Å; I68-W159 HydrophobicContact CG2-CZ2 3.63Å
69S84.4Confident87.4Confident41 Ų4145.1 Ų45.129%0.28725%0.252SS..  trans-125.5150.8172.9-177.10000110.4H71 D72S69-H71 PolarHBondContact O-N 2.9Å; S69-H71 WeakPolarHBondContact OG-CB 3.33Å; S69-H71 PolarHBondContact OG-N 2.97Å; S69-H71 VanDerWaalsContact OG-N 3.13Å; S69-H71 PolarHBondContact OG-ND1 3.49Å; S69-H71 VanDerWaalsContact OG-ND1 3.1Å; S69-D72 WeakPolarHBondContact CB-OD1 3.35Å; S69-D72 PolarHBondContact N-OD2 2.87Å; S69-D72 PolarHBondContact O-N 2.88Å
70S79.5Confident87.2Confident9 Ų935.5 Ų35.56%0.06321%0.207CC..G310 helixtrans-59.6-26.9166.8500000111.1D72 L73 R283S70-D72 PolarHBondContact O-N 3.01Å; S70-L73 WeakPolarHBondContact O-CB 3.29Å; S70-L73 PolarHBondContact O-N 3.02Å; S70-R283 PolarHBondContact O-NE 2.86Å; S70-R283 PolarHBondContact O-NH1 2.77Å; S70-R283 PolarHBondContact O-NH2 2.83Å
71H80.1Confident87Confident63 Ų6332 Ų3229%0.29219%0.189SC..G310 helixtrans-69.2-11.6178.8-61.581.1000114S69 L73 H74 D320S69-H71 PolarHBondContact O-N 2.9Å; S69-H71 WeakPolarHBondContact OG-CB 3.33Å; S69-H71 PolarHBondContact OG-N 2.97Å; S69-H71 VanDerWaalsContact OG-N 3.13Å; S69-H71 PolarHBondContact OG-ND1 3.49Å; S69-H71 VanDerWaalsContact OG-ND1 3.1Å; H71-L73 PolarHBondContact O-N 3.01Å; H71-H74 PolarHBondContact O-CE1 2.83Å; H71-D320 IonicContact NE2-OD2 2.76Å; H71-D320 PolarHBondContact NE2-OD2 2.71Å
72D80.7Confident86.8Confident11 Ų1132.1 Ų32.16%0.05919%0.189CC..G310 helixtrans-83.93.6178.4-44.7-23.7000111.8S69 S70 H151 S152 E157 W159 S160S69-D72 WeakPolarHBondContact CB-OD1 3.35Å; S69-D72 PolarHBondContact N-OD2 2.87Å; S69-D72 PolarHBondContact O-N 2.88Å; S70-D72 PolarHBondContact O-N 3.01Å; D72-H151 CarbonylContact O-C 3.5Å; D72-S152 WeakPolarHBondContact O-CA 3.37Å; D72-S152 PolarHBondContact O-N 2.93Å; D72-E157 VanDerWaalsContact CB-OE2 3.26Å; D72-E157 WeakPolarHBondContact CB-OE2 3.49Å; D72-W159 HydrophobicContact CB-CZ2 3.88Å; D72-W159 PolarHBondContact OD2-NE1 2.77Å; D72-S160 PolarHBondContact O-OG 3.08Å; D72-S160 VanDerWaalsContact O-OG 3.07Å
73L84.3Confident86.8Confident0 Ų030.2 Ų30.20%018%0.18CC..  trans-118.2105.1-172.3-66.4163.7000110.2S70 H71 V84 C87 S88 W159 R283S70-L73 WeakPolarHBondContact O-CB 3.29Å; S70-L73 PolarHBondContact O-N 3.02Å; H71-L73 PolarHBondContact O-N 3.01Å; L73-V84 HydrophobicContact CB-CG1 3.86Å; L73-C87 HydrophobicContact CD1-CB 3.51Å; L73-C87 HydrophobicContact CD2-CB 3.64Å; L73-C87 HydrophobicContact CG-CB 4.24Å; L73-S88 VanDerWaalsContact CD1-CA 3.48Å; L73-W159 HydrophobicContact CD1-CH2 3.91Å; L73-W159 HydrophobicContact CD1-CZ2 4.4Å; L73-W159 HydrophobicContact CD2-CH2 3.7Å; L73-W159 HydrophobicContact CD2-CZ2 4.18Å; L73-W159 HydrophobicContact CD2-CZ3 4.23Å; L73-W159 HydrophobicContact CG-CH2 3.84Å; L73-W159 HydrophobicContact CG-CZ2 4.04Å; L73-R283 PolarHBondContact O-NH1 3.24Å; L73-R283 PolarHBondContact O-NH2 3.43Å
74H85.7Confident86.7Confident14 Ų1430.2 Ų30.27%0.06518%0.18CC..BIsolated β-bridgetrans-120.9134.6169.5-61.779.9000109.6H71 C150 H151 N153 W286H71-H74 PolarHBondContact O-CE1 2.83Å; H74-C150 VanDerWaalsContact O-CA 3.28Å; H74-C150 WeakPolarHBondContact O-CA 3.46Å; H74-C150 PolarHBondContact O-SG 3.13Å; H74-H151 WeakPolarHBondContact CB-O 3.46Å; H74-H151 PolarHBondContact N-O 2.72Å; H74-H151 PolarHBondContact ND1-O 2.62Å; H74-H151 PolarHBondContact O-N 3Å; H74-N153 PolarHBondContact CE1-ND2 2.8Å; H74-N153 PolarHBondContact CE1-OD1 3.26Å; H74-N153 VanDerWaalsContact CE1-OD1 3.22Å; H74-N153 PolarHBondContact ND1-OD1 2.82Å; H74-N153 PolarHBondContact NE2-ND2 3.01Å; H74-N153 PolarHBondContact NE2-OD1 2.87Å; H74-W286 PolarHBondContact CD2-O 3.33Å
75Q88.2Confident86.6Confident24 Ų2429.1 Ų29.111%0.11218%0.175CC..  trans-68.1138.4173.3-172.2179.5-14.300110.7L78 V84 P285Q75-L78 PolarHBondContact NE2-O 3.43Å; Q75-V84 HydrophobicContact CB-CG2 4.18Å; Q75-V84 HydrophobicContact CG-CG2 4.44Å; Q75-P285 PolarHBondContact N-O 2.93Å
76G90.2Very high86.8Confident21 Ų2127.5 Ų27.522%0.21617%0.165CC..  trans-87.4-144.6171.400000112.7L78 I148 Y149G76-L78 VanDerWaalsContact C-N 3.29Å; G76-L78 PolarHBondContact O-N 3.49Å; G76-I148 CarbonylContact C-O 3.52Å; G76-I148 VanDerWaalsContact CA-O 3.28Å; G76-I148 WeakPolarHBondContact CA-O 2.92Å; G76-Y149 WeakPolarHBondContact CA-O 3.25Å
77I88.8Confident87.2Confident96 Ų9619.3 Ų19.349%0.49212%0.121SC..SBendtrans-80-6.1-17770.3175000114.4M143 I148 Y149I77-M143 HydrophobicContact CD1-CE 3.75Å; I77-I148 HydrophobicContact CD1-CB 4.18Å; I77-I148 HydrophobicContact CD1-CD1 4.2Å; I77-I148 HydrophobicContact CD1-CG1 4.44Å; I77-I148 HydrophobicContact CG1-CB 4.45Å; I77-I148 WeakPolarHBondContact CG1-O 3.34Å; I77-I148 PolarHBondContact N-O 3.27Å; I77-Y149 HydrophobicContact CG1-CD1 4.38Å; I77-Y149 HydrophobicContact CG1-CE1 4.21Å
78L88.2Confident87.5Confident17 Ų1717.6 Ų17.69%0.08910%0.104CC..SBendtrans-92.8143.5-175.1-171.366.1000110.8Q75 G76 N80 Y149 Y174 L177 D178Q75-L78 PolarHBondContact NE2-O 3.43Å; G76-L78 VanDerWaalsContact C-N 3.29Å; G76-L78 PolarHBondContact O-N 3.49Å; L78-N80 HydrophobicContact CD2-CB 3.99Å; L78-N80 HydrophobicContact CG-CB 4.13Å; L78-N80 PolarHBondContact O-N 3.29Å; L78-N80 PolarHBondContact O-OD1 3.4Å; L78-Y149 HydrophobicContact CB-CD1 3.85Å; L78-Y149 HydrophobicContact CB-CE1 3.98Å; L78-Y149 HydrophobicContact CD2-CD1 4.38Å; L78-Y149 HydrophobicContact CD2-CE1 4.34Å; L78-Y174 VanDerWaalsContact CD2-O 3.25Å; L78-Y174 WeakPolarHBondContact CD2-O 3.45Å; L78-L177 HydrophobicContact CD2-CB 3.95Å; L78-D178 HydrophobicContact CD1-CB 3.84Å
79G86.8Confident87.8Confident24 Ų2416.2 Ų16.225%0.24710%0.097CC..SBendtrans-74.148.6174.800000113.8D178 G179G79-D178 VanDerWaalsContact CA-OD1 3.23Å; G79-D178 WeakPolarHBondContact CA-OD1 3.48Å; G79-D178 PolarHBondContact N-OD1 3.05Å; G79-G179 PolarHBondContact O-N 3.42Å; G79-G179 VanDerWaalsContact O-N 3.08Å
80N88.8Confident88Confident0 Ų014.5 Ų14.50%08%0.084CC..  trans-110.729.1-177.774.5-22.8000113.4L78 W82 F83 V84 E164 L177L78-N80 HydrophobicContact CD2-CB 3.99Å; L78-N80 HydrophobicContact CG-CB 4.13Å; L78-N80 PolarHBondContact O-N 3.29Å; L78-N80 PolarHBondContact O-OD1 3.4Å; N80-W82 PolarHBondContact O-N 2.93Å; N80-F83 HydrophobicContact CB-CB 4.41Å; N80-F83 WeakPolarHBondContact O-CB 3.25Å; N80-F83 PolarHBondContact O-N 2.82Å; N80-V84 PolarHBondContact O-N 2.79Å; N80-E164 PolarHBondContact ND2-OE1 3.18Å; N80-L177 HydrophobicContact CB-CB 4.24Å; N80-L177 WeakPolarHBondContact CB-O 3.36Å
81C88.8Confident88.4Confident11 Ų1114.7 Ų14.77%0.0749%0.087CC..Hα-helixtrans-45-38.7175.155.10000113.6F83 V84 A85 H252C81-F83 VanDerWaalsContact C-N 3.29Å; C81-F83 PolarHBondContact O-N 3.35Å; C81-V84 PolarHBondContact O-N 3.44Å; C81-A85 WeakPolarHBondContact O-CB 3.02Å; C81-A85 PolarHBondContact O-N 2.82Å; C81-H252 WeakPolarHBondContact CB-CE1 3.1Å; C81-H252 WeakPolarHBondContact CB-ND1 3.39Å
82W92.6Very high88.5Confident8 Ų814.5 Ų14.53%0.039%0.087CC..Hα-helixtrans-56.1-38.8176.268.5-91.3000113.4N80 A86 Y167 L177 G180 S181 A182 A185 A253 R411N80-W82 PolarHBondContact O-N 2.93Å; W82-A86 WeakPolarHBondContact O-CB 3.43Å; W82-A86 PolarHBondContact O-N 2.95Å; W82-A86 VanDerWaalsContact O-N 3.1Å; W82-Y167 AromaticContact CH2-CE1 3.61Å; W82-Y167 HydrophobicContact CH2-CE1 3.61Å; W82-Y167 HydrophobicContact CZ2-CE1 4.37Å; W82-Y167 HydrophobicContact CZ3-CE1 4.14Å; W82-L177 HydrophobicContact CZ2-CD2 4.49Å; W82-L177 PolarHBondContact NE1-O 2.94Å; W82-G180 VanDerWaalsContact CD1-N 3.33Å; W82-G180 VanDerWaalsContact CE2-CA 3.5Å; W82-G180 VanDerWaalsContact CG-C 3.49Å; W82-S181 VanDerWaalsContact CE3-C 3.43Å; W82-S181 VanDerWaalsContact CZ3-O 3.3Å; W82-S181 WeakPolarHBondContact CZ3-O 3.46Å; W82-A182 HydrophobicContact CB-CB 4.35Å; W82-A182 WeakPolarHBondContact O-CA 3.38Å; W82-A182 WeakPolarHBondContact O-CB 3.22Å; W82-A185 HydrophobicContact CE3-CB 3.78Å; W82-A185 HydrophobicContact CZ3-CB 3.45Å; W82-A185 VanDerWaalsContact CZ3-CB 3.45Å; W82-A253 HydrophobicContact CB-CB 4.44Å; W82-R411 VanDerWaalsContact CH2-NH1 3.34Å
83F94.1Very high88.8Confident1 Ų116.4 Ų16.40%0.00410%0.096CC..Hα-helixtrans-72.6-46176.9169.1-94.5000110.4N80 C81 A85 A86 C87 L163 E164 Y167 F189N80-F83 HydrophobicContact CB-CB 4.41Å; N80-F83 WeakPolarHBondContact O-CB 3.25Å; N80-F83 PolarHBondContact O-N 2.82Å; C81-F83 VanDerWaalsContact C-N 3.29Å; C81-F83 PolarHBondContact O-N 3.35Å; F83-A85 VanDerWaalsContact C-N 3.31Å; F83-A85 PolarHBondContact O-N 2.75Å; F83-A86 WeakPolarHBondContact O-CB 3.38Å; F83-A86 PolarHBondContact O-N 2.97Å; F83-A86 VanDerWaalsContact O-N 3.13Å; F83-C87 VanDerWaalsContact CZ-SG 3.5Å; F83-C87 PolarHBondContact O-N 2.78Å; F83-C87 PolarHBondContact O-SG 2.73Å; F83-C87 VanDerWaalsContact O-SG 3.38Å; F83-L163 HydrophobicContact CZ-CG 4.26Å; F83-E164 HydrophobicContact CD1-CG 4.3Å; F83-E164 HydrophobicContact CE1-CB 3.67Å; F83-E164 HydrophobicContact CE1-CG 3.8Å; F83-E164 HydrophobicContact CZ-CB 4Å; F83-E164 HydrophobicContact CZ-CG 4.34Å; F83-Y167 AromaticContact CD2-CD1 3.32Å; F83-Y167 HydrophobicContact CD2-CD1 3.32Å; F83-Y167 AromaticContact CD2-CE1 3.55Å; F83-Y167 HydrophobicContact CD2-CE1 3.55Å; F83-Y167 HydrophobicContact CD2-CG 4.02Å; F83-Y167 AromaticContact CE2-CD1 3.37Å; F83-Y167 HydrophobicContact CE2-CD1 3.37Å; F83-Y167 HydrophobicContact CE2-CD2 4.35Å; F83-Y167 AromaticContact CE2-CE1 3.98Å; F83-Y167 HydrophobicContact CE2-CE1 3.98Å; F83-Y167 AromaticContact CE2-CG 3.57Å; F83-Y167 HydrophobicContact CE2-CG 3.57Å; F83-Y167 HydrophobicContact CG-CD1 4.35Å; F83-Y167 HydrophobicContact CZ-CD1 4.45Å; F83-F189 AromaticContact CD2-CZ 3.84Å; F83-F189 HydrophobicContact CD2-CZ 3.84Å; F83-F189 HydrophobicContact CE2-CE1 4.05Å; F83-F189 AromaticContact CE2-CZ 3.52Å; F83-F189 HydrophobicContact CE2-CZ 3.52Å; F83-F189 HydrophobicContact CZ-CZ 4.33Å
84V90.9Very high88.9Confident0 Ų022.4 Ų22.40%012%0.124CC..Hα-helixtrans-64.4-37.6179.8-173.20000111.1L73 Q75 N80 C81 C87 S88 P285L73-V84 HydrophobicContact CB-CG1 3.86Å; Q75-V84 HydrophobicContact CB-CG2 4.18Å; Q75-V84 HydrophobicContact CG-CG2 4.44Å; N80-V84 PolarHBondContact O-N 2.79Å; C81-V84 PolarHBondContact O-N 3.44Å; V84-C87 PolarHBondContact O-N 2.98Å; V84-S88 WeakPolarHBondContact O-CB 3.42Å; V84-S88 PolarHBondContact O-N 2.92Å; V84-S88 PolarHBondContact O-OG 3.21Å; V84-P285 HydrophobicContact CB-CB 3.9Å; V84-P285 HydrophobicContact CG1-CB 3.73Å
85A90Very high88.8Confident0 Ų026.1 Ų26.10%015%0.148CC..Hα-helixtrans-61.7-47.9170.800000111.3C81 F83 C87 S88 C89 A253 S255 P285C81-A85 WeakPolarHBondContact O-CB 3.02Å; C81-A85 PolarHBondContact O-N 2.82Å; F83-A85 VanDerWaalsContact C-N 3.31Å; F83-A85 PolarHBondContact O-N 2.75Å; A85-C87 VanDerWaalsContact C-N 3.33Å; A85-C87 PolarHBondContact O-N 2.89Å; A85-S88 WeakPolarHBondContact O-CB 3.39Å; A85-S88 PolarHBondContact O-N 2.86Å; A85-C89 PolarHBondContact O-N 3.05Å; A85-A253 HydrophobicContact CB-CB 3.84Å; A85-S255 VanDerWaalsContact CA-OG 3.29Å; A85-S255 WeakPolarHBondContact CA-OG 3.36Å; A85-S255 PolarHBondContact O-OG 2.91Å; A85-P285 HydrophobicContact CB-CG 3.71Å
86A92.9Very high88.8Confident0 Ų025.3 Ų25.30%015%0.145CC..Hα-helixtrans-60.7-40.9176.900000112.6W82 F83 S88 C89 L90 A185 I186 F189W82-A86 WeakPolarHBondContact O-CB 3.43Å; W82-A86 PolarHBondContact O-N 2.95Å; W82-A86 VanDerWaalsContact O-N 3.1Å; F83-A86 WeakPolarHBondContact O-CB 3.38Å; F83-A86 PolarHBondContact O-N 2.97Å; F83-A86 VanDerWaalsContact O-N 3.13Å; A86-S88 VanDerWaalsContact C-N 3.3Å; A86-S88 PolarHBondContact O-N 3.24Å; A86-C89 WeakPolarHBondContact O-CB 3.22Å; A86-C89 PolarHBondContact O-N 2.83Å; A86-L90 PolarHBondContact O-N 2.83Å; A86-A185 HydrophobicContact CB-CB 3.35Å; A86-I186 HydrophobicContact CB-CG1 3.69Å; A86-F189 HydrophobicContact CB-CD2 4.2Å; A86-F189 HydrophobicContact CB-CE2 3.63Å
87C91.7Very high88.7Confident1 Ų125.1 Ų25.11%0.00714%0.137CC..Hα-helixtrans-63.4-37.2173.5-69.90000111.5L73 F83 V84 A85 C89 L90 A91 F189L73-C87 HydrophobicContact CD1-CB 3.51Å; L73-C87 HydrophobicContact CD2-CB 3.64Å; L73-C87 HydrophobicContact CG-CB 4.24Å; F83-C87 VanDerWaalsContact CZ-SG 3.5Å; F83-C87 PolarHBondContact O-N 2.78Å; F83-C87 PolarHBondContact O-SG 2.73Å; F83-C87 VanDerWaalsContact O-SG 3.38Å; V84-C87 PolarHBondContact O-N 2.98Å; A85-C87 VanDerWaalsContact C-N 3.33Å; A85-C87 PolarHBondContact O-N 2.89Å; C87-C89 VanDerWaalsContact C-N 3.33Å; C87-C89 PolarHBondContact O-N 2.68Å; C87-L90 WeakPolarHBondContact O-CB 3.35Å; C87-L90 PolarHBondContact O-N 2.89Å; C87-L90 VanDerWaalsContact O-N 3.14Å; C87-A91 PolarHBondContact O-N 3.31Å; C87-F189 VanDerWaalsContact SG-CZ 3.56Å
88S89.1Confident88.9Confident0 Ų024.1 Ų24.10%013%0.131CC..Hα-helixtrans-65.7-38.9177-61.20000111L73 V84 A85 A86 S255 R283L73-S88 VanDerWaalsContact CD1-CA 3.48Å; V84-S88 WeakPolarHBondContact O-CB 3.42Å; V84-S88 PolarHBondContact O-N 2.92Å; V84-S88 PolarHBondContact O-OG 3.21Å; A85-S88 WeakPolarHBondContact O-CB 3.39Å; A85-S88 PolarHBondContact O-N 2.86Å; A86-S88 VanDerWaalsContact C-N 3.3Å; A86-S88 PolarHBondContact O-N 3.24Å; S88-S255 WeakPolarHBondContact CB-OG 3.35Å; S88-R283 PolarHBondContact OG-NH1 3.35Å
89C88.5Confident89Confident0 Ų028.3 Ų28.30%015%0.148CC..Hα-helixtrans-63.4-42.5170.3-68.70000111.9A85 A86 C87 A91 L92 I186 L227 I228A85-C89 PolarHBondContact O-N 3.05Å; A86-C89 WeakPolarHBondContact O-CB 3.22Å; A86-C89 PolarHBondContact O-N 2.83Å; C87-C89 VanDerWaalsContact C-N 3.33Å; C87-C89 PolarHBondContact O-N 2.68Å; C89-A91 VanDerWaalsContact C-N 3.33Å; C89-A91 PolarHBondContact O-N 2.83Å; C89-L92 WeakPolarHBondContact O-CB 3.17Å; C89-L92 PolarHBondContact O-N 2.86Å; C89-I186 HydrophobicContact CB-CD1 4.39Å; C89-L227 HydrophobicContact CB-CB 4.08Å; C89-L227 HydrophobicContact CB-CD1 4.08Å; C89-L227 HydrophobicContact CB-CD2 4.08Å; C89-L227 HydrophobicContact CB-CG 4.3Å; C89-L227 WeakPolarHBondContact O-CD2 3.47Å; C89-I228 PolarHBondContact SG-O 2.82Å; C89-I228 VanDerWaalsContact SG-O 3.39Å
90L88.6Confident89.5Confident4 Ų427.1 Ų27.12%0.02114%0.136CC..Hα-helixtrans-61.7-40.2179.1-178.265000112.1A86 C87 L92 Q93 L96 W97 V100 F189 T190A86-L90 PolarHBondContact O-N 2.83Å; C87-L90 WeakPolarHBondContact O-CB 3.35Å; C87-L90 PolarHBondContact O-N 2.89Å; C87-L90 VanDerWaalsContact O-N 3.14Å; L90-L92 PolarHBondContact O-N 2.94Å; L90-L92 VanDerWaalsContact O-N 3.14Å; L90-Q93 PolarHBondContact O-N 2.82Å; L90-L96 HydrophobicContact CD1-CB 3.71Å; L90-W97 HydrophobicContact CD1-CB 4.14Å; L90-W97 HydrophobicContact CD2-CB 4.2Å; L90-W97 HydrophobicContact CG-CB 3.83Å; L90-V100 HydrophobicContact CD1-CG2 4.36Å; L90-V100 HydrophobicContact CD2-CB 4.21Å; L90-V100 HydrophobicContact CD2-CG1 4.3Å; L90-V100 HydrophobicContact CD2-CG2 3.92Å; L90-F189 HydrophobicContact CB-CD2 4.26Å; L90-F189 HydrophobicContact CD1-CB 4.06Å; L90-F189 HydrophobicContact CD2-CB 4.05Å; L90-F189 HydrophobicContact CD2-CD2 4.04Å; L90-F189 HydrophobicContact CD2-CG 3.95Å; L90-T190 HydrophobicContact CD1-CG2 4.42Å
91A87.3Confident89.7Confident14 Ų1427.2 Ų27.212%0.11614%0.137CC..Hα-helixtrans-57.1-26.6177.100000113.2I68 C87 C89 Q93I68-A91 HydrophobicContact CG2-CB 3.55Å; C87-A91 PolarHBondContact O-N 3.31Å; C89-A91 VanDerWaalsContact C-N 3.33Å; C89-A91 PolarHBondContact O-N 2.83Å; A91-Q93 PolarHBondContact O-N 3.28Å
92L83.1Confident89.9Confident58 Ų5826.9 Ų26.930%0.30413%0.134SC..THydrogen-bonded Turntrans-74.9-9.8177.7-56.2172.4000113.8C89 L90 T257C89-L92 WeakPolarHBondContact O-CB 3.17Å; C89-L92 PolarHBondContact O-N 2.86Å; L90-L92 PolarHBondContact O-N 2.94Å; L90-L92 VanDerWaalsContact O-N 3.14Å; L92-T257 HydrophobicContact CD1-CG2 4.11Å
93Q86.6Confident89.9Confident52 Ų5230.3 Ų30.324%0.24315%0.153CC..  trans-128.592.7-172.4-68-62.2-44.600111.4L90 A91 T95 L96 W97 L227L90-Q93 PolarHBondContact O-N 2.82Å; A91-Q93 PolarHBondContact O-N 3.28Å; Q93-T95 VanDerWaalsContact C-N 3.29Å; Q93-T95 PolarHBondContact O-N 2.96Å; Q93-L96 HydrophobicContact CB-CB 3.97Å; Q93-L96 HydrophobicContact CB-CD1 3.67Å; Q93-L96 HydrophobicContact CB-CG 3.89Å; Q93-L96 HydrophobicContact CG-CD1 3.97Å; Q93-L96 PolarHBondContact O-N 2.78Å; Q93-W97 PolarHBondContact O-N 3.24Å; Q93-L227 HydrophobicContact CG-CD2 3.66Å
94E85.2Confident89.7Confident125 Ų12532.7 Ų32.758%0.58416%0.163SC*.Hα-helixtrans-53.5-45.7-173.4-160.5-172.6160.200113.3L96 W97 Q98E94-L96 PolarHBondContact O-N 2.87Å; E94-W97 HydrophobicContact CG-CZ2 4.33Å; E94-W97 VanDerWaalsContact O-CD1 3.25Å; E94-W97 PolarHBondContact O-N 3.49Å; E94-W97 PolarHBondContact O-NE1 3.47Å; E94-Q98 WeakPolarHBondContact O-CG 3.31Å; E94-Q98 PolarHBondContact O-N 3.17Å; E94-Q98 PolarHBondContact OE1-NE2 2.82Å; E94-Q98 VanDerWaalsContact OE1-NE2 3.15Å
95T85.6Confident89.7Confident93 Ų9340.5 Ų40.557%0.57120%0.198SC*.Hα-helixtrans-68.4-19.6-178.665.20000114.4Q93Q93-T95 VanDerWaalsContact C-N 3.29Å; Q93-T95 PolarHBondContact O-N 2.96Å
96L87.9Confident89.7Confident7 Ų746.1 Ų46.14%0.03722%0.224CC..Hα-helixtrans-87.8-45.3178.8-65-179.8000110.6L90 Q93 E94 Q98 K99 V100 T190 L227 I342L90-L96 HydrophobicContact CD1-CB 3.71Å; Q93-L96 HydrophobicContact CB-CB 3.97Å; Q93-L96 HydrophobicContact CB-CD1 3.67Å; Q93-L96 HydrophobicContact CB-CG 3.89Å; Q93-L96 HydrophobicContact CG-CD1 3.97Å; Q93-L96 PolarHBondContact O-N 2.78Å; E94-L96 PolarHBondContact O-N 2.87Å; L96-Q98 VanDerWaalsContact C-N 3.29Å; L96-Q98 PolarHBondContact O-N 2.84Å; L96-K99 WeakPolarHBondContact O-CB 3.43Å; L96-K99 PolarHBondContact O-N 3.25Å; L96-V100 PolarHBondContact O-N 2.84Å; L96-T190 HydrophobicContact CB-CG2 4.41Å; L96-T190 HydrophobicContact CD1-CG2 3.82Å; L96-T190 HydrophobicContact CD2-CG2 4.46Å; L96-T190 HydrophobicContact CG-CG2 4.46Å; L96-L227 HydrophobicContact CD1-CD1 4.29Å; L96-I342 HydrophobicContact CD1-CD1 3.82Å; L96-I342 HydrophobicContact CD1-CG1 4.09Å; L96-I342 HydrophobicContact CD2-CD1 4.23Å
97W88.1Confident89.7Confident17 Ų1746.4 Ų46.46%0.06423%0.225CC..Hα-helixtrans-65.6-34179.978.7-112.9000112F64 I68 L90 Q93 E94 K99 V100 I101 F104F64-W97 HydrophobicContact CE1-CZ3 4.45Å; F64-W97 HydrophobicContact CZ-CZ3 4.05Å; I68-W97 HydrophobicContact CD1-CB 4.16Å; I68-W97 HydrophobicContact CD1-CD2 3.27Å; I68-W97 HydrophobicContact CD1-CE3 3.34Å; I68-W97 HydrophobicContact CD1-CG 3.64Å; I68-W97 HydrophobicContact CD1-CH2 4.21Å; I68-W97 HydrophobicContact CD1-CZ2 4.16Å; I68-W97 HydrophobicContact CD1-CZ3 3.82Å; I68-W97 HydrophobicContact CG1-CD2 4.29Å; I68-W97 HydrophobicContact CG1-CE3 4.49Å; I68-W97 HydrophobicContact CG1-CZ2 4.42Å; L90-W97 HydrophobicContact CD1-CB 4.14Å; L90-W97 HydrophobicContact CD2-CB 4.2Å; L90-W97 HydrophobicContact CG-CB 3.83Å; Q93-W97 PolarHBondContact O-N 3.24Å; E94-W97 HydrophobicContact CG-CZ2 4.33Å; E94-W97 VanDerWaalsContact O-CD1 3.25Å; E94-W97 PolarHBondContact O-N 3.49Å; E94-W97 PolarHBondContact O-NE1 3.47Å; W97-K99 PolarHBondContact O-N 2.87Å; W97-K99 VanDerWaalsContact O-N 3.1Å; W97-V100 CarbonylContact O-C 3.46Å; W97-V100 WeakPolarHBondContact O-CA 3.46Å; W97-V100 WeakPolarHBondContact O-CB 3.43Å; W97-V100 PolarHBondContact O-N 3Å; W97-I101 HydrophobicContact CE3-CB 4.15Å; W97-I101 HydrophobicContact CE3-CD1 4.37Å; W97-I101 HydrophobicContact CE3-CG1 4.38Å; W97-I101 HydrophobicContact CZ3-CB 4.27Å; W97-I101 PolarHBondContact O-N 2.93Å; W97-F104 AromaticContact CH2-CD1 3.67Å; W97-F104 HydrophobicContact CH2-CD1 3.67Å; W97-F104 AromaticContact CH2-CD2 3.96Å; W97-F104 HydrophobicContact CH2-CD2 3.96Å; W97-F104 AromaticContact CH2-CE1 3.73Å; W97-F104 HydrophobicContact CH2-CE1 3.73Å; W97-F104 HydrophobicContact CH2-CE2 4.01Å; W97-F104 AromaticContact CH2-CG 3.79Å; W97-F104 HydrophobicContact CH2-CG 3.79Å; W97-F104 AromaticContact CH2-CZ 3.89Å; W97-F104 HydrophobicContact CH2-CZ 3.89Å; W97-F104 HydrophobicContact CZ3-CB 4.1Å; W97-F104 AromaticContact CZ3-CD1 3.83Å; W97-F104 HydrophobicContact CZ3-CD1 3.83Å; W97-F104 HydrophobicContact CZ3-CD2 4.38Å; W97-F104 HydrophobicContact CZ3-CE1 4.33Å; W97-F104 AromaticContact CZ3-CG 3.86Å; W97-F104 HydrophobicContact CZ3-CG 3.86Å
98Q91.6Very high89.9Confident75 Ų7548.8 Ų48.835%0.3524%0.236SC..Hα-helixtrans-62-19.6175.5-72.9176.94.400113.1E94 L96 F104E94-Q98 WeakPolarHBondContact O-CG 3.31Å; E94-Q98 PolarHBondContact O-N 3.17Å; E94-Q98 PolarHBondContact OE1-NE2 2.82Å; E94-Q98 VanDerWaalsContact OE1-NE2 3.15Å; L96-Q98 VanDerWaalsContact C-N 3.29Å; L96-Q98 PolarHBondContact O-N 2.84Å; Q98-F104 HydrophobicContact CG-CE1 4.36Å
99K92Very high90.1Very high104 Ų10449.6 Ų49.645%0.45224%0.239SC..Hα-helixtrans-78.5-34.3170.8-63.6178-176.9173.50112L96 W97 R124 W131L96-K99 WeakPolarHBondContact O-CB 3.43Å; L96-K99 PolarHBondContact O-N 3.25Å; W97-K99 PolarHBondContact O-N 2.87Å; W97-K99 VanDerWaalsContact O-N 3.1Å; K99-R124 WeakPolarHBondContact O-CB 3.48Å; K99-W131 HydrophobicContact CB-CH2 4.01Å; K99-W131 HydrophobicContact CB-CZ2 4.37Å; K99-W131 HydrophobicContact CB-CZ3 4.49Å; K99-W131 HydrophobicContact CD-CZ2 4.21Å
100V95.4Very high90.2Very high0 Ų052.5 Ų52.50%026%0.255CS..Hα-helixtrans-77.4-39.1179.8178.20000111.4L90 L96 W97 P102 F123 R124 F125 L163 F189L90-V100 HydrophobicContact CD1-CG2 4.36Å; L90-V100 HydrophobicContact CD2-CB 4.21Å; L90-V100 HydrophobicContact CD2-CG1 4.3Å; L90-V100 HydrophobicContact CD2-CG2 3.92Å; L96-V100 PolarHBondContact O-N 2.84Å; W97-V100 CarbonylContact O-C 3.46Å; W97-V100 WeakPolarHBondContact O-CA 3.46Å; W97-V100 WeakPolarHBondContact O-CB 3.43Å; W97-V100 PolarHBondContact O-N 3Å; V100-P102 VanDerWaalsContact C-CD 3.46Å; V100-P102 WeakPolarHBondContact O-CD 3.39Å; V100-F123 CarbonylContact O-C 3.52Å; V100-F123 VanDerWaalsContact O-CA 3.27Å; V100-F123 WeakPolarHBondContact O-CA 3.42Å; V100-R124 WeakPolarHBondContact CA-O 3.47Å; V100-R124 PolarHBondContact O-N 2.87Å; V100-F125 HydrophobicContact CG1-CE1 4.42Å; V100-L163 HydrophobicContact CG1-CD1 3.57Å; V100-F189 HydrophobicContact CG1-CD1 4.5Å; V100-F189 HydrophobicContact CG2-CB 3.97Å; V100-F189 HydrophobicContact CG2-CD1 4.5Å; V100-F189 WeakPolarHBondContact CG2-O 3.46Å
101I94.5Very high90.2Very high2 Ų257.2 Ų57.21%0.0129%0.285CS..SBendtrans-114.577.2175.5-40.3-179.1000107.8F64 I68 W97 F104 F123 W159F64-I101 HydrophobicContact CE1-CD1 3.97Å; F64-I101 HydrophobicContact CZ-CD1 3.74Å; F64-I101 HydrophobicContact CZ-CG2 4.1Å; I68-I101 HydrophobicContact CD1-CD1 4.19Å; W97-I101 HydrophobicContact CE3-CB 4.15Å; W97-I101 HydrophobicContact CE3-CD1 4.37Å; W97-I101 HydrophobicContact CE3-CG1 4.38Å; W97-I101 HydrophobicContact CZ3-CB 4.27Å; W97-I101 PolarHBondContact O-N 2.93Å; I101-F104 HydrophobicContact CG2-CB 4.07Å; I101-F123 HydrophobicContact CB-CD1 4.5Å; I101-F123 HydrophobicContact CD1-CE1 4.11Å; I101-F123 HydrophobicContact CG1-CD1 3.9Å; I101-F123 HydrophobicContact CG1-CE1 3.94Å; I101-F123 HydrophobicContact CG2-CD1 4.34Å; I101-F123 HydrophobicContact CG2-CE1 4.09Å; I101-W159 HydrophobicContact CD1-CB 4.45Å; I101-W159 HydrophobicContact CD1-CE3 3.98Å
102P92.9Very high90.5Very high4 Ų465.3 Ų65.33%0.02632%0.318CS..THydrogen-bonded Turntrans-66.1156.1-179.832.7-39.3000110.7V100 F104 Q107 H122 R124V100-P102 VanDerWaalsContact C-CD 3.46Å; V100-P102 WeakPolarHBondContact O-CD 3.39Å; P102-F104 PolarHBondContact O-N 2.97Å; P102-Q107 PolarHBondContact O-NE2 3.36Å; P102-H122 VanDerWaalsContact CG-CE1 3.47Å; P102-H122 WeakPolarHBondContact CG-CE1 3.14Å; P102-R124 HydrophobicContact CG-CG 4.03Å
103D91.6Very high90.9Very high80 Ų8066.9 Ų66.943%0.42832%0.322SS..THydrogen-bonded Turntrans51.130.1170.5-48.5-45000113.5K105 E106 Q107D103-K105 PolarHBondContact O-N 3.37Å; D103-E106 WeakPolarHBondContact O-CA 3.38Å; D103-E106 WeakPolarHBondContact O-CB 3.32Å; D103-E106 PolarHBondContact O-N 2.93Å; D103-Q107 PolarHBondContact O-N 3.43Å
104F89.8Confident91.1Very high50 Ų5068.1 Ų68.122%0.21934%0.335CS..Hα-helixtrans-54.8-32.7-166.671.1-90.8000113.7F64 W97 Q98 I101 P102 E106 Q107 E108F64-F104 HydrophobicContact CD2-CD2 4.12Å; F64-F104 HydrophobicContact CE2-CB 3.78Å; F64-F104 AromaticContact CE2-CD2 3.91Å; F64-F104 HydrophobicContact CE2-CD2 3.91Å; F64-F104 HydrophobicContact CE2-CG 4.23Å; F64-F104 HydrophobicContact CZ-CB 4.29Å; W97-F104 AromaticContact CH2-CD1 3.67Å; W97-F104 HydrophobicContact CH2-CD1 3.67Å; W97-F104 AromaticContact CH2-CD2 3.96Å; W97-F104 HydrophobicContact CH2-CD2 3.96Å; W97-F104 AromaticContact CH2-CE1 3.73Å; W97-F104 HydrophobicContact CH2-CE1 3.73Å; W97-F104 HydrophobicContact CH2-CE2 4.01Å; W97-F104 AromaticContact CH2-CG 3.79Å; W97-F104 HydrophobicContact CH2-CG 3.79Å; W97-F104 AromaticContact CH2-CZ 3.89Å; W97-F104 HydrophobicContact CH2-CZ 3.89Å; W97-F104 HydrophobicContact CZ3-CB 4.1Å; W97-F104 AromaticContact CZ3-CD1 3.83Å; W97-F104 HydrophobicContact CZ3-CD1 3.83Å; W97-F104 HydrophobicContact CZ3-CD2 4.38Å; W97-F104 HydrophobicContact CZ3-CE1 4.33Å; W97-F104 AromaticContact CZ3-CG 3.86Å; W97-F104 HydrophobicContact CZ3-CG 3.86Å; Q98-F104 HydrophobicContact CG-CE1 4.36Å; I101-F104 HydrophobicContact CG2-CB 4.07Å; P102-F104 PolarHBondContact O-N 2.97Å; F104-E106 VanDerWaalsContact C-N 3.3Å; F104-E106 PolarHBondContact O-N 3.34Å; F104-Q107 PolarHBondContact O-N 3.22Å; F104-E108 PolarHBondContact O-N 2.94Å; F104-E108 VanDerWaalsContact O-N 3.14Å
105K90.8Very high91.4Very high165 Ų16567.6 Ų67.672%0.71733%0.332SS*.Hα-helixtrans-65.6-29.3175.5-62.5-176.3-179.8178.60113.6D103D103-K105 PolarHBondContact O-N 3.37Å
106E90.5Very high91.7Very high117 Ų11768.3 Ų68.355%0.54733%0.328SS..Hα-helixtrans-85-16.6177.6-56.7-172.3171.900112.7K17 D103 F104K17-E106 PolarHBondContact NZ-O 3.18Å; D103-E106 WeakPolarHBondContact O-CA 3.38Å; D103-E106 WeakPolarHBondContact O-CB 3.32Å; D103-E106 PolarHBondContact O-N 2.93Å; F104-E106 VanDerWaalsContact C-N 3.3Å; F104-E106 PolarHBondContact O-N 3.34Å
107Q94Very high92Very high7 Ų769.9 Ų69.93%0.03333%0.333CS..Hα-helixtrans-86.5-23.3173.8-55.4-162.258.100112.2L63 P102 D103 F104 F121 H122L63-Q107 HydrophobicContact CD2-CB 3.81Å; P102-Q107 PolarHBondContact O-NE2 3.36Å; D103-Q107 PolarHBondContact O-N 3.43Å; F104-Q107 PolarHBondContact O-N 3.22Å; Q107-F121 HydrophobicContact CB-CD1 4.02Å; Q107-F121 HydrophobicContact CB-CE1 4.26Å; Q107-F121 WeakPolarHBondContact O-CE1 3.28Å; Q107-H122 PolarHBondContact NE2-CD2 2.91Å; Q107-H122 PolarHBondContact NE2-NE2 2.82Å; Q107-H122 PolarHBondContact NE2-O 2.99Å; Q107-H122 PolarHBondContact OE1-CD2 3.07Å; Q107-H122 PolarHBondContact OE1-O 2.92Å
108E93.9Very high92.4Very high50 Ų5069.2 Ų69.223%0.23433%0.332CS..SBendtrans-58.4147.5-179.5-171.255.5-84.800113.1H62 L63 F64 F104 D110H62-E108 WeakPolarHBondContact CA-OE1 3.02Å; L63-E108 WeakPolarHBondContact CB-OE2 3.49Å; L63-E108 VanDerWaalsContact N-CD 3.34Å; L63-E108 PolarHBondContact N-OE1 3.05Å; L63-E108 PolarHBondContact N-OE2 3.47Å; F64-E108 PolarHBondContact N-OE2 2.94Å; F64-E108 VanDerWaalsContact N-OE2 3.17Å; F104-E108 PolarHBondContact O-N 2.94Å; F104-E108 VanDerWaalsContact O-N 3.14Å; E108-D110 PolarHBondContact O-N 3.47Å
109W93.8Very high92.7Very high17 Ų1765.6 Ų65.66%0.06432%0.315CS..  trans-67.4113169.6-73.3-90.4000109.7P54 P61 H62 L63 P111 Y117 F121 F158 L162P54-W109 HydrophobicContact CB-CH2 4.17Å; P54-W109 HydrophobicContact CB-CZ2 3.8Å; P54-W109 HydrophobicContact CG-CH2 3.85Å; P54-W109 HydrophobicContact CG-CZ2 3.66Å; P61-W109 HydrophobicContact CB-CD2 4.21Å; P61-W109 HydrophobicContact CB-CZ2 4.46Å; P61-W109 HydrophobicContact CG-CD2 4.23Å; P61-W109 HydrophobicContact CG-CG 4.18Å; P61-W109 VanDerWaalsContact O-CB 3.26Å; P61-W109 WeakPolarHBondContact O-CB 3.49Å; H62-W109 VanDerWaalsContact C-CE3 3.43Å; H62-W109 VanDerWaalsContact C-CZ3 3.41Å; L63-W109 HydrophobicContact CB-CE3 4.23Å; L63-W109 HydrophobicContact CB-CZ3 3.94Å; L63-W109 HydrophobicContact CD1-CZ3 4.22Å; L63-W109 VanDerWaalsContact N-CE3 3.31Å; L63-W109 VanDerWaalsContact N-CZ3 3.31Å; W109-P111 WeakPolarHBondContact O-CD 3.36Å; W109-Y117 AromaticContact CD1-CD2 3.58Å; W109-Y117 AromaticContact CD1-CE2 3.77Å; W109-Y117 AromaticContact CE2-CE2 3.91Å; W109-Y117 HydrophobicContact CZ2-CE2 4.35Å; W109-Y117 AromaticContact NE1-CD2 3.41Å; W109-Y117 AromaticContact NE1-CE2 3.07Å; W109-Y117 AromaticContact NE1-CZ 3.78Å; W109-F121 HydrophobicContact CD2-CZ 4.36Å; W109-F121 AromaticContact CE2-CZ 3.92Å; W109-F121 HydrophobicContact CE3-CZ 4.29Å; W109-F121 HydrophobicContact CH2-CE1 4.01Å; W109-F121 HydrophobicContact CH2-CE2 4.08Å; W109-F121 AromaticContact CH2-CZ 3.39Å; W109-F121 HydrophobicContact CH2-CZ 3.39Å; W109-F121 HydrophobicContact CZ2-CE1 4.43Å; W109-F121 AromaticContact CZ2-CE2 3.92Å; W109-F121 HydrophobicContact CZ2-CE2 3.92Å; W109-F121 AromaticContact CZ2-CZ 3.43Å; W109-F121 HydrophobicContact CZ2-CZ 3.43Å; W109-F121 VanDerWaalsContact CZ2-CZ 3.43Å; W109-F121 HydrophobicContact CZ3-CE1 4.07Å; W109-F121 AromaticContact CZ3-CZ 3.83Å; W109-F121 HydrophobicContact CZ3-CZ 3.83Å; W109-F158 HydrophobicContact CH2-CB 4.17Å; W109-F158 HydrophobicContact CZ3-CB 4.42Å; W109-L162 HydrophobicContact CH2-CD1 4.07Å
110D91.5Very high93Very high61 Ų6160.9 Ų60.933%0.32630%0.295SS..  trans-102.3104.8176.4-173.6-6.6000110.4E108 K112 K113E108-D110 PolarHBondContact O-N 3.47Å; D110-K112 PolarHBondContact O-N 2.85Å; D110-K112 VanDerWaalsContact O-N 3.15Å; D110-K112 WeakPolarHBondContact OD1-CA 3.35Å; D110-K112 VanDerWaalsContact OD1-CB 3.26Å; D110-K112 WeakPolarHBondContact OD1-CB 3.44Å; D110-K112 PolarHBondContact OD1-N 2.8Å; D110-K113 HydrophobicContact CB-CB 4.21Å; D110-K113 CarbonylContact O-C 3.59Å; D110-K113 PolarHBondContact O-N 2.84Å
111P88.6Confident93.2Very high103 Ų10361 Ų6167%0.66930%0.295SS*.THydrogen-bonded Turntrans-64.4-18.4178.326.3-34.2000112.7W109 K113W109-P111 WeakPolarHBondContact O-CD 3.36Å; P111-K113 VanDerWaalsContact C-N 3.35Å
112K92.6Very high93.3Very high184 Ų18461 Ų6180%0.830%0.295SS*.THydrogen-bonded Turntrans-83.2-14.4175.1-57.3176.8179.8173.50112.6D110D110-K112 PolarHBondContact O-N 2.85Å; D110-K112 VanDerWaalsContact O-N 3.15Å; D110-K112 WeakPolarHBondContact OD1-CA 3.35Å; D110-K112 VanDerWaalsContact OD1-CB 3.26Å; D110-K112 WeakPolarHBondContact OD1-CB 3.44Å; D110-K112 PolarHBondContact OD1-N 2.8Å
113K92.2Very high93.6Very high91 Ų9160.9 Ų60.940%0.39629%0.294SS..  trans-137.658-179.2-62.3-179.9-174.1162.30111.2D110 P111 E115 K116D110-K113 HydrophobicContact CB-CB 4.21Å; D110-K113 CarbonylContact O-C 3.59Å; D110-K113 PolarHBondContact O-N 2.84Å; P111-K113 VanDerWaalsContact C-N 3.35Å; K113-E115 VanDerWaalsContact CA-OE2 3.29Å; K113-E115 WeakPolarHBondContact CA-OE2 3.4Å; K113-E115 WeakPolarHBondContact CB-OE1 3.32Å; K113-E115 PolarHBondContact O-N 2.81Å; K113-E115 VanDerWaalsContact O-N 3.13Å; K113-K116 HydrophobicContact CB-CB 4.44Å; K113-K116 HydrophobicContact CB-CD 4.03Å; K113-K116 HydrophobicContact CB-CG 4.09Å; K113-K116 HydrophobicContact CD-CD 3.89Å; K113-K116 WeakPolarHBondContact O-CB 3.44Å; K113-K116 PolarHBondContact O-N 2.92Å
114P90.6Very high93.9Very high78 Ų7860.1 Ų60.151%0.50629%0.285SS..G310 helixtrans-60.3-24.9-176.927-35.8000112.9K116 Y117P114-K116 PolarHBondContact O-N 2.86Å; P114-Y117 PolarHBondContact O-N 3.1Å
115E90.9Very high94.2Very high114 Ų11457.7 Ų57.753%0.53328%0.275SS..G310 helixtrans-66.7-16.7175.974.8-70166.200114.1K113K113-E115 VanDerWaalsContact CA-OE2 3.29Å; K113-E115 WeakPolarHBondContact CA-OE2 3.4Å; K113-E115 WeakPolarHBondContact CB-OE1 3.32Å; K113-E115 PolarHBondContact O-N 2.81Å; K113-E115 VanDerWaalsContact O-N 3.13Å
116K92.3Very high94.4Very high109 Ų10950.3 Ų50.347%0.47424%0.242SC..G310 helixtrans-85.3-14.8176-68.5-168.6171-162.70113.6K17 K113 P114K17-K116 WeakPolarHBondContact CE-O 3.12Å; K113-K116 HydrophobicContact CB-CB 4.44Å; K113-K116 HydrophobicContact CB-CD 4.03Å; K113-K116 HydrophobicContact CB-CG 4.09Å; K113-K116 HydrophobicContact CD-CD 3.89Å; K113-K116 WeakPolarHBondContact O-CB 3.44Å; K113-K116 PolarHBondContact O-N 2.92Å; P114-K116 PolarHBondContact O-N 2.86Å
117Y95.3Very high94.6Very high39 Ų3946.5 Ų46.515%0.15323%0.228CC..  trans-77.2125.3175.9169.6-101.3000109.9L26 K55 W109 P114 D138L26-Y117 HydrophobicContact CD1-CE1 4.4Å; L26-Y117 HydrophobicContact CD2-CD1 3.91Å; L26-Y117 HydrophobicContact CD2-CE1 3.47Å; L26-Y117 VanDerWaalsContact CD2-CE1 3.47Å; K55-Y117 HydrophobicContact CD-CE1 4.08Å; W109-Y117 AromaticContact CD1-CD2 3.58Å; W109-Y117 AromaticContact CD1-CE2 3.77Å; W109-Y117 AromaticContact CE2-CE2 3.91Å; W109-Y117 HydrophobicContact CZ2-CE2 4.35Å; W109-Y117 AromaticContact NE1-CD2 3.41Å; W109-Y117 AromaticContact NE1-CE2 3.07Å; W109-Y117 AromaticContact NE1-CZ 3.78Å; P114-Y117 PolarHBondContact O-N 3.1Å; Y117-D138 VanDerWaalsContact CE2-OD2 3.3Å; Y117-D138 WeakPolarHBondContact CE2-OD2 3.48Å; Y117-D138 VanDerWaalsContact CZ-OD2 3.32Å; Y117-D138 PolarHBondContact OH-OD1 3.48Å; Y117-D138 PolarHBondContact OH-OD2 3.27Å
118A96.8Very high94.5Very high3 Ų347.8 Ų47.83%0.02523%0.234CC..  trans-130.316.2179.300000112.7K17 C20 I21 F27 I120K17-A118 HydrophobicContact CG-CB 4.39Å; C20-A118 HydrophobicContact CB-CB 3.75Å; I21-A118 HydrophobicContact CG1-CB 4.01Å; F27-A118 WeakPolarHBondContact CB-O 3.32Å; F27-A118 PolarHBondContact N-O 2.82Å; A118-I120 VanDerWaalsContact C-N 3.28Å; A118-I120 HydrophobicContact CB-CG2 3.92Å; A118-I120 PolarHBondContact O-N 3.33Å
119G97.4Very high94.5Very high0 Ų046 Ų460%023%0.229CC..SBendtrans59.834.9179.300000113.9R53 D137 D138R53-G119 PolarHBondContact NH1-O 2.85Å; G119-D137 WeakPolarHBondContact O-CA 3.29Å; G119-D137 WeakPolarHBondContact O-CB 3.31Å; G119-D138 PolarHBondContact O-N 2.79Å
120I98.3Very high94.5Very high5 Ų548.7 Ų48.73%0.02624%0.242CC..EExtended strand (participates in β ladder)trans-134.5134.7-173.6-172.7174.2000110.4Y13 L16 K17 F27 A118 V135Y13-I120 HydrophobicContact CD2-CD1 4.15Å; Y13-I120 HydrophobicContact CD2-CG1 4.01Å; Y13-I120 HydrophobicContact CE2-CG1 4.1Å; Y13-I120 HydrophobicContact CE2-CG2 4.11Å; L16-I120 HydrophobicContact CB-CD1 3.62Å; K17-I120 HydrophobicContact CB-CD1 4.48Å; K17-I120 HydrophobicContact CB-CG2 3.83Å; K17-I120 HydrophobicContact CD-CG2 4.2Å; K17-I120 HydrophobicContact CG-CG2 3.85Å; F27-I120 HydrophobicContact CB-CB 3.72Å; F27-I120 HydrophobicContact CB-CD1 4.29Å; F27-I120 HydrophobicContact CB-CG1 4.25Å; F27-I120 HydrophobicContact CD1-CB 3.89Å; F27-I120 HydrophobicContact CD1-CD1 3.77Å; F27-I120 HydrophobicContact CD1-CG1 3.56Å; F27-I120 HydrophobicContact CD2-CD1 4.12Å; F27-I120 HydrophobicContact CE1-CD1 4.1Å; F27-I120 HydrophobicContact CE1-CG1 4.09Å; F27-I120 HydrophobicContact CE2-CD1 4.42Å; F27-I120 HydrophobicContact CG-CB 4Å; F27-I120 HydrophobicContact CG-CD1 3.8Å; F27-I120 HydrophobicContact CG-CG1 3.95Å; F27-I120 HydrophobicContact CZ-CD1 4.42Å; A118-I120 VanDerWaalsContact C-N 3.28Å; A118-I120 HydrophobicContact CB-CG2 3.92Å; A118-I120 PolarHBondContact O-N 3.33Å; I120-V135 HydrophobicContact CD1-CG1 3.66Å; I120-V135 HydrophobicContact CG1-CG1 3.62Å
121F98.3Very high94.6Very high2 Ų248 Ų481%0.00924%0.235CC..EExtended strand (participates in β ladder)trans-136.4160.9-177.7-65.8-94.8000109.8L63 Q107 W109 F123 V135 V136 D138 L162L63-F121 HydrophobicContact CD1-CD1 4.05Å; L63-F121 HydrophobicContact CD1-CE1 3.91Å; L63-F121 HydrophobicContact CD2-CD1 4.26Å; L63-F121 HydrophobicContact CD2-CE1 4.2Å; Q107-F121 HydrophobicContact CB-CD1 4.02Å; Q107-F121 HydrophobicContact CB-CE1 4.26Å; Q107-F121 WeakPolarHBondContact O-CE1 3.28Å; W109-F121 HydrophobicContact CD2-CZ 4.36Å; W109-F121 AromaticContact CE2-CZ 3.92Å; W109-F121 HydrophobicContact CE3-CZ 4.29Å; W109-F121 HydrophobicContact CH2-CE1 4.01Å; W109-F121 HydrophobicContact CH2-CE2 4.08Å; W109-F121 AromaticContact CH2-CZ 3.39Å; W109-F121 HydrophobicContact CH2-CZ 3.39Å; W109-F121 HydrophobicContact CZ2-CE1 4.43Å; W109-F121 AromaticContact CZ2-CE2 3.92Å; W109-F121 HydrophobicContact CZ2-CE2 3.92Å; W109-F121 AromaticContact CZ2-CZ 3.43Å; W109-F121 HydrophobicContact CZ2-CZ 3.43Å; W109-F121 VanDerWaalsContact CZ2-CZ 3.43Å; W109-F121 HydrophobicContact CZ3-CE1 4.07Å; W109-F121 AromaticContact CZ3-CZ 3.83Å; W109-F121 HydrophobicContact CZ3-CZ 3.83Å; F121-F123 HydrophobicContact CB-CE2 4.09Å; F121-V135 CarbonylContact O-C 3.6Å; F121-V135 WeakPolarHBondContact O-CA 3.46Å; F121-V136 HydrophobicContact CB-CG2 4.23Å; F121-V136 PolarHBondContact N-O 2.92Å; F121-V136 PolarHBondContact O-N 2.98Å; F121-D138 HydrophobicContact CD2-CB 3.9Å; F121-D138 HydrophobicContact CE2-CB 3.6Å; F121-L162 HydrophobicContact CD1-CD1 4Å; F121-L162 HydrophobicContact CD2-CD1 3.97Å; F121-L162 HydrophobicContact CD2-CD2 4.49Å; F121-L162 HydrophobicContact CE1-CD1 4.11Å; F121-L162 HydrophobicContact CE2-CD1 4.12Å; F121-L162 HydrophobicContact CG-CD1 3.94Å; F121-L162 HydrophobicContact CZ-CD1 4.19Å
122H97.9Very high95Very high3 Ų343.6 Ų43.61%0.01421%0.206CC..EExtended strand (participates in β ladder)trans-142.2145.8174.274.9134.1000112.8Y13 P102 Q107 E133 V134 V135Y13-H122 AromaticContact CD1-CD2 3.51Å; Y13-H122 AromaticContact CD1-CE1 3.79Å; Y13-H122 AromaticContact CD1-CG 3.83Å; Y13-H122 AromaticContact CD1-ND1 3.98Å; Y13-H122 AromaticContact CD1-NE2 3.51Å; Y13-H122 HydrophobicContact CD2-CB 3.89Å; Y13-H122 AromaticContact CD2-CD2 3.88Å; Y13-H122 AromaticContact CD2-CG 3.96Å; Y13-H122 AromaticContact CE1-CD2 3.54Å; Y13-H122 AromaticContact CE1-NE2 3.51Å; Y13-H122 AromaticContact CE2-CD2 3.92Å; Y13-H122 HydrophobicContact CG-CB 3.92Å; Y13-H122 AromaticContact CG-CD2 3.68Å; Y13-H122 AromaticContact CG-CG 3.63Å; Y13-H122 AromaticContact CZ-CD2 3.75Å; P102-H122 VanDerWaalsContact CG-CE1 3.47Å; P102-H122 WeakPolarHBondContact CG-CE1 3.14Å; Q107-H122 PolarHBondContact NE2-CD2 2.91Å; Q107-H122 PolarHBondContact NE2-NE2 2.82Å; Q107-H122 PolarHBondContact NE2-O 2.99Å; Q107-H122 PolarHBondContact OE1-CD2 3.07Å; Q107-H122 PolarHBondContact OE1-O 2.92Å; H122-E133 HydrophobicContact CB-CG 4.21Å; H122-E133 IonicContact CE1-OE2 3Å; H122-E133 PolarHBondContact CE1-OE2 3.38Å; H122-E133 IonicContact ND1-OE1 3.04Å; H122-E133 IonicContact ND1-OE2 3.1Å; H122-E133 PolarHBondContact ND1-OE2 2.92Å; H122-V134 VanDerWaalsContact CA-O 3.27Å; H122-V134 WeakPolarHBondContact CA-O 3.42Å; H122-V135 HydrophobicContact CB-CG2 4.25Å
123F97.9Very high95.3Very high0 Ų035.8 Ų35.80%017%0.172CC..EExtended strand (participates in β ladder)trans-130.7159.9-178.5-60.8-87.9000109.7V100 I101 F121 F125 E133 V134 V136 L162 L163 A166V100-F123 CarbonylContact O-C 3.52Å; V100-F123 VanDerWaalsContact O-CA 3.27Å; V100-F123 WeakPolarHBondContact O-CA 3.42Å; I101-F123 HydrophobicContact CB-CD1 4.5Å; I101-F123 HydrophobicContact CD1-CE1 4.11Å; I101-F123 HydrophobicContact CG1-CD1 3.9Å; I101-F123 HydrophobicContact CG1-CE1 3.94Å; I101-F123 HydrophobicContact CG2-CD1 4.34Å; I101-F123 HydrophobicContact CG2-CE1 4.09Å; F121-F123 HydrophobicContact CB-CE2 4.09Å; F123-F125 HydrophobicContact CB-CE2 3.77Å; F123-F125 HydrophobicContact CB-CZ 3.98Å; F123-E133 CarbonylContact O-C 3.56Å; F123-E133 WeakPolarHBondContact O-CA 3.38Å; F123-V134 PolarHBondContact N-O 3.29Å; F123-V134 PolarHBondContact O-N 3Å; F123-V136 HydrophobicContact CD2-CG2 4.16Å; F123-V136 HydrophobicContact CE2-CG2 3.85Å; F123-L162 HydrophobicContact CE2-CB 3.91Å; F123-L162 WeakPolarHBondContact CE2-O 3.45Å; F123-L162 HydrophobicContact CZ-CB 3.59Å; F123-L163 HydrophobicContact CB-CD1 4.4Å; F123-L163 HydrophobicContact CD1-CB 4.27Å; F123-L163 HydrophobicContact CD1-CD1 3.5Å; F123-L163 HydrophobicContact CE1-CB 3.95Å; F123-L163 HydrophobicContact CE1-CD1 4.04Å; F123-L163 HydrophobicContact CG-CD1 4.11Å; F123-L163 HydrophobicContact CZ-CB 4.45Å; F123-A166 HydrophobicContact CB-CB 4.03Å; F123-A166 HydrophobicContact CD2-CB 3.4Å; F123-A166 HydrophobicContact CE2-CB 4.14Å; F123-A166 HydrophobicContact CG-CB 3.91Å
124R97.5Very high95.6Very high64 Ų6431.5 Ų31.524%0.24215%0.153CC..EExtended strand (participates in β ladder)trans-124.4132.8175.9-66.2177.5179.5155.98.7110.8V5 K99 V100 P102 W131 T132 E133V5-R124 HydrophobicContact CG1-CG 4.49Å; K99-R124 WeakPolarHBondContact O-CB 3.48Å; V100-R124 WeakPolarHBondContact CA-O 3.47Å; V100-R124 PolarHBondContact O-N 2.87Å; P102-R124 HydrophobicContact CG-CG 4.03Å; R124-W131 HydrophobicContact CB-CE3 3.96Å; R124-W131 HydrophobicContact CB-CZ3 4.35Å; R124-T132 CarbonylContact C-O 3.59Å; R124-T132 VanDerWaalsContact CA-O 3.27Å; R124-T132 WeakPolarHBondContact CA-O 3.48Å; R124-E133 HydrophobicContact CG-CB 4.29Å; R124-E133 IonicContact CZ-OE2 3.47Å; R124-E133 IonicContact NE-OE2 3.25Å; R124-E133 PolarHBondContact NE-OE2 3.45Å; R124-E133 IonicContact NH2-OE2 3.17Å; R124-E133 PolarHBondContact NH2-OE2 2.88Å
125F97.2Very high95.9Very high0 Ų027.8 Ų27.80%013%0.129CC..EExtended strand (participates in β ladder)trans-125.3140.3175.4-54.6-83.9000109.4V100 F123 C127 W131 T132 V134 L163 A166 Y167 L170 D188 F189V100-F125 HydrophobicContact CG1-CE1 4.42Å; F123-F125 HydrophobicContact CB-CE2 3.77Å; F123-F125 HydrophobicContact CB-CZ 3.98Å; F125-C127 PolarHBondContact O-N 3.29Å; F125-W131 CarbonylContact O-C 3.53Å; F125-T132 PolarHBondContact N-O 3.34Å; F125-T132 PolarHBondContact O-N 2.81Å; F125-V134 HydrophobicContact CD2-CB 4.38Å; F125-V134 HydrophobicContact CD2-CG2 3.76Å; F125-V134 HydrophobicContact CE2-CB 4.2Å; F125-V134 HydrophobicContact CE2-CG2 4.03Å; F125-L163 HydrophobicContact CE1-CD1 3.76Å; F125-L163 HydrophobicContact CZ-CD1 3.73Å; F125-A166 HydrophobicContact CE2-CB 3.88Å; F125-A166 HydrophobicContact CZ-CB 4.02Å; F125-Y167 AromaticContact CD1-CD2 3.74Å; F125-Y167 HydrophobicContact CD1-CD2 3.74Å; F125-Y167 HydrophobicContact CD1-CE2 4.16Å; F125-Y167 AromaticContact CE1-CD2 3.61Å; F125-Y167 HydrophobicContact CE1-CD2 3.61Å; F125-Y167 HydrophobicContact CE1-CE2 4.41Å; F125-Y167 HydrophobicContact CE1-CG 4.34Å; F125-Y167 HydrophobicContact CG-CD2 4.34Å; F125-Y167 HydrophobicContact CZ-CD2 4.07Å; F125-L170 HydrophobicContact CB-CD1 3.77Å; F125-L170 HydrophobicContact CD1-CD1 4.49Å; F125-L170 HydrophobicContact CD2-CD1 3.2Å; F125-L170 HydrophobicContact CD2-CG 4.29Å; F125-L170 HydrophobicContact CE2-CD1 3.81Å; F125-L170 HydrophobicContact CG-CD1 3.57Å; F125-D188 CarbonylContact C-O 3.59Å; F125-D188 WeakPolarHBondContact CA-O 3.43Å; F125-F189 AromaticContact CD1-CD1 3.93Å; F125-F189 HydrophobicContact CD1-CD1 3.93Å; F125-F189 AromaticContact CD1-CE1 3.94Å; F125-F189 HydrophobicContact CD1-CE1 3.94Å; F125-F189 HydrophobicContact CE1-CD1 4.1Å; F125-F189 AromaticContact CE1-CE1 3.76Å; F125-F189 HydrophobicContact CE1-CE1 3.76Å
126W95.6Very high96.3Very high9 Ų922.3 Ų22.33%0.03410%0.104CC..EExtended strand (participates in β ladder)trans-76.996.9170.9-170.682.2000109G129 E130 W131 V187 D188 G191 M358 I486W126-G129 VanDerWaalsContact CZ2-N 3.33Å; W126-G129 VanDerWaalsContact NE1-C 3.31Å; W126-G129 PolarHBondContact NE1-O 3.49Å; W126-G129 VanDerWaalsContact NE1-O 3.15Å; W126-E130 CarbonylContact C-O 3.53Å; W126-E130 WeakPolarHBondContact CA-O 3.34Å; W126-W131 HydrophobicContact CB-CD2 4.3Å; W126-W131 HydrophobicContact CB-CE3 4.21Å; W126-W131 HydrophobicContact CB-CH2 4.34Å; W126-W131 HydrophobicContact CB-CZ2 4.39Å; W126-W131 HydrophobicContact CB-CZ3 4.24Å; W126-W131 AromaticContact CD1-NE1 3.96Å; W126-V187 HydrophobicContact CE3-CG1 3.57Å; W126-V187 HydrophobicContact CZ3-CG1 3.44Å; W126-V187 VanDerWaalsContact CZ3-CG1 3.44Å; W126-D188 PolarHBondContact N-O 3.46Å; W126-D188 WeakPolarHBondContact O-CA 2.99Å; W126-G191 VanDerWaalsContact CD2-CA 3.48Å; W126-M358 HydrophobicContact CZ2-SD 4.39Å; W126-I486 HydrophobicContact CH2-CD1 3.49Å; W126-I486 VanDerWaalsContact CH2-CD1 3.49Å; W126-I486 HydrophobicContact CZ2-CD1 4.26Å; W126-I486 HydrophobicContact CZ3-CD1 4.25Å
127C94Very high96.6Very high38 Ų3817.2 Ų17.226%0.2578%0.082SC..EExtended strand (participates in β ladder)trans-100.7110.7179.1-60.90000108.9F125 G129 E130F125-C127 PolarHBondContact O-N 3.29Å; C127-G129 VanDerWaalsContact C-N 3.3Å; C127-G129 PolarHBondContact O-N 2.88Å; C127-G129 VanDerWaalsContact O-N 3.1Å; C127-E130 PolarHBondContact N-O 2.89Å; C127-E130 PolarHBondContact O-N 3.39Å
128F92.7Very high96.7Very high34 Ų3415.4 Ų15.415%0.1498%0.075CC..THydrogen-bonded Turntrans52.841.1164.6-162.1-113.8000115.3Q406 E408 K484 F485 I486F128-Q406 HydrophobicContact CD2-CG 4.4Å; F128-Q406 WeakPolarHBondContact CE2-O 3.19Å; F128-E408 HydrophobicContact CD1-CG 3.89Å; F128-E408 HydrophobicContact CD2-CG 4.13Å; F128-E408 HydrophobicContact CE1-CG 3.54Å; F128-E408 HydrophobicContact CE2-CB 4.36Å; F128-E408 HydrophobicContact CE2-CG 3.82Å; F128-E408 VanDerWaalsContact CE2-N 3.28Å; F128-E408 HydrophobicContact CG-CG 4.15Å; F128-E408 HydrophobicContact CZ-CB 4.43Å; F128-E408 HydrophobicContact CZ-CG 3.46Å; F128-E408 VanDerWaalsContact CZ-CG 3.46Å; F128-K484 HydrophobicContact CE1-CB 4.1Å; F128-K484 HydrophobicContact CZ-CB 4.03Å; F128-F485 VanDerWaalsContact CZ-CA 3.41Å; F128-I486 HydrophobicContact CD1-CG2 3.88Å; F128-I486 HydrophobicContact CD2-CD1 4.33Å; F128-I486 HydrophobicContact CD2-CG1 4.2Å; F128-I486 HydrophobicContact CD2-CG2 4.08Å; F128-I486 HydrophobicContact CE1-CG2 3.7Å; F128-I486 HydrophobicContact CE2-CB 4.37Å; F128-I486 HydrophobicContact CE2-CG1 4.1Å; F128-I486 HydrophobicContact CE2-CG2 3.88Å; F128-I486 HydrophobicContact CG-CG2 4.09Å; F128-I486 HydrophobicContact CZ-CG2 3.72Å; F128-I486 WeakPolarHBondContact O-CG2 3.43Å
129G92.5Very high96.8Very high12 Ų1216.3 Ų16.312%0.1248%0.079CC..THydrogen-bonded Turntrans113.9-25.8-179.900000114.1W126 C127W126-G129 VanDerWaalsContact CZ2-N 3.33Å; W126-G129 VanDerWaalsContact NE1-C 3.31Å; W126-G129 PolarHBondContact NE1-O 3.49Å; W126-G129 VanDerWaalsContact NE1-O 3.15Å; C127-G129 VanDerWaalsContact C-N 3.3Å; C127-G129 PolarHBondContact O-N 2.88Å; C127-G129 VanDerWaalsContact O-N 3.1Å
130E93.5Very high96.9Very high74 Ų7416.4 Ų16.435%0.3468%0.079SC..EExtended strand (participates in β ladder)trans-130.7144.7-163.9-62.5-178.4126.100111.5Q6 W126 C127Q6-E130 VanDerWaalsContact CD-OE2 3.28Å; Q6-E130 VanDerWaalsContact NE2-CD 3.32Å; Q6-E130 PolarHBondContact NE2-OE2 2.86Å; W126-E130 CarbonylContact C-O 3.53Å; W126-E130 WeakPolarHBondContact CA-O 3.34Å; C127-E130 PolarHBondContact N-O 2.89Å; C127-E130 PolarHBondContact O-N 3.39Å
131W95.3Very high96.8Very high47 Ų4716.3 Ų16.318%0.1788%0.079CC..EExtended strand (participates in β ladder)trans-76.2127.1172.6-75.1100.3000109.2V5 Q6 K99 R124 F125 W126 F189V5-W131 CarbonylContact C-O 3.52Å; V5-W131 WeakPolarHBondContact CA-O 3.44Å; V5-W131 HydrophobicContact CG1-CB 4.45Å; V5-W131 HydrophobicContact CG2-CB 4.32Å; Q6-W131 PolarHBondContact N-O 2.91Å; K99-W131 HydrophobicContact CB-CH2 4.01Å; K99-W131 HydrophobicContact CB-CZ2 4.37Å; K99-W131 HydrophobicContact CB-CZ3 4.49Å; K99-W131 HydrophobicContact CD-CZ2 4.21Å; R124-W131 HydrophobicContact CB-CE3 3.96Å; R124-W131 HydrophobicContact CB-CZ3 4.35Å; F125-W131 CarbonylContact O-C 3.53Å; W126-W131 HydrophobicContact CB-CD2 4.3Å; W126-W131 HydrophobicContact CB-CE3 4.21Å; W126-W131 HydrophobicContact CB-CH2 4.34Å; W126-W131 HydrophobicContact CB-CZ2 4.39Å; W126-W131 HydrophobicContact CB-CZ3 4.24Å; W126-W131 AromaticContact CD1-NE1 3.96Å; W131-F189 WeakPolarHBondContact CH2-O 3.42Å
132T96.6Very high96.8Very high9 Ų916.2 Ų16.26%0.0558%0.079CC..EExtended strand (participates in β ladder)trans-117.8123.7-179.6-57.50000109.2Q6 F8 R124 F125Q6-T132 CarbonylContact O-C 3.59Å; Q6-T132 VanDerWaalsContact O-CA 3.31Å; Q6-T132 WeakPolarHBondContact O-CA 3.34Å; F8-T132 HydrophobicContact CB-CG2 3.88Å; R124-T132 CarbonylContact C-O 3.59Å; R124-T132 VanDerWaalsContact CA-O 3.27Å; R124-T132 WeakPolarHBondContact CA-O 3.48Å; F125-T132 PolarHBondContact N-O 3.34Å; F125-T132 PolarHBondContact O-N 2.81Å
133E97.7Very high96.6Very high21 Ų2117.2 Ų17.210%0.0988%0.084CC..EExtended strand (participates in β ladder)trans-85.5131.8174-175.5166.299.500110.5V5 Q6 L7 F8 H122 F123 R124V5-E133 HydrophobicContact CG1-CB 3.71Å; Q6-E133 PolarHBondContact O-N 2.88Å; L7-E133 HydrophobicContact CD2-CB 4.24Å; F8-E133 WeakPolarHBondContact CB-O 3.31Å; F8-E133 PolarHBondContact N-O 2.72Å; H122-E133 HydrophobicContact CB-CG 4.21Å; H122-E133 IonicContact CE1-OE2 3Å; H122-E133 PolarHBondContact CE1-OE2 3.38Å; H122-E133 IonicContact ND1-OE1 3.04Å; H122-E133 IonicContact ND1-OE2 3.1Å; H122-E133 PolarHBondContact ND1-OE2 2.92Å; F123-E133 CarbonylContact O-C 3.56Å; F123-E133 WeakPolarHBondContact O-CA 3.38Å; R124-E133 HydrophobicContact CG-CB 4.29Å; R124-E133 IonicContact CZ-OE2 3.47Å; R124-E133 IonicContact NE-OE2 3.25Å; R124-E133 PolarHBondContact NE-OE2 3.45Å; R124-E133 IonicContact NH2-OE2 3.17Å; R124-E133 PolarHBondContact NH2-OE2 2.88Å
134V98.4Very high96.4Very high0 Ų022.8 Ų22.80%011%0.114CC..EExtended strand (participates in β ladder)trans-125.3116.6-177.1-175.30000108F8 H122 F123 F125 V136 A166 K169 L170F8-V134 HydrophobicContact CB-CG2 4Å; F8-V134 HydrophobicContact CD1-CG1 4.32Å; F8-V134 HydrophobicContact CG-CG2 4.37Å; H122-V134 VanDerWaalsContact CA-O 3.27Å; H122-V134 WeakPolarHBondContact CA-O 3.42Å; F123-V134 PolarHBondContact N-O 3.29Å; F123-V134 PolarHBondContact O-N 3Å; F125-V134 HydrophobicContact CD2-CB 4.38Å; F125-V134 HydrophobicContact CD2-CG2 3.76Å; F125-V134 HydrophobicContact CE2-CB 4.2Å; F125-V134 HydrophobicContact CE2-CG2 4.03Å; V134-V136 HydrophobicContact CG1-CG1 4.47Å; V134-A166 HydrophobicContact CB-CB 4.47Å; V134-A166 HydrophobicContact CG1-CB 4.11Å; V134-K169 HydrophobicContact CG1-CB 4.5Å; V134-K169 HydrophobicContact CG1-CD 3.92Å; V134-K169 HydrophobicContact CG1-CG 4.29Å; V134-L170 HydrophobicContact CG1-CG 4.46Å; V134-L170 HydrophobicContact CG2-CD1 3.79Å; V134-L170 HydrophobicContact CG2-CD2 3.48Å; V134-L170 VanDerWaalsContact CG2-CD2 3.48Å; V134-L170 HydrophobicContact CG2-CG 3.57Å
135V98.5Very high96.1Very high0 Ų021.5 Ų21.50%012%0.12CC..EExtended strand (participates in β ladder)trans-90.3140.2176.1-177.50000108.9Q11 L16 F27 I120 F121 H122 K169Q11-V135 HydrophobicContact CB-CB 4.28Å; Q11-V135 HydrophobicContact CB-CG2 4.11Å; L16-V135 HydrophobicContact CD1-CG1 4.28Å; F27-V135 HydrophobicContact CE1-CG1 3.89Å; F27-V135 HydrophobicContact CZ-CG1 4.27Å; I120-V135 HydrophobicContact CD1-CG1 3.66Å; I120-V135 HydrophobicContact CG1-CG1 3.62Å; F121-V135 CarbonylContact O-C 3.6Å; F121-V135 WeakPolarHBondContact O-CA 3.46Å; H122-V135 HydrophobicContact CB-CG2 4.25Å; V135-K169 PolarHBondContact O-NZ 2.83Å
136V98.8Very high95.9Very high0 Ų029 Ų290%015%0.153CC..EExtended strand (participates in β ladder)trans-139.2151.4172.9-67.80000110.2F121 F123 V134 K165 A166 K169F121-V136 HydrophobicContact CB-CG2 4.23Å; F121-V136 PolarHBondContact N-O 2.92Å; F121-V136 PolarHBondContact O-N 2.98Å; F123-V136 HydrophobicContact CD2-CG2 4.16Å; F123-V136 HydrophobicContact CE2-CG2 3.85Å; V134-V136 HydrophobicContact CG1-CG1 4.47Å; V136-K165 HydrophobicContact CB-CD 4.37Å; V136-K165 HydrophobicContact CG1-CG 4.36Å; V136-A166 HydrophobicContact CG1-CB 3.86Å; V136-A166 HydrophobicContact CG2-CB 4.35Å; V136-K169 HydrophobicContact CG1-CD 3.95Å
137D98.6Very high95.9Very high2 Ų230.4 Ų30.41%0.01116%0.161CC..EExtended strand (participates in β ladder)trans-78.8170.4160.370.652.6000111.5F27 D29 G119 L139 K165F27-D137 HydrophobicContact CB-CB 4.49Å; F27-D137 HydrophobicContact CD1-CB 3.68Å; F27-D137 HydrophobicContact CE1-CB 4.36Å; F27-D137 HydrophobicContact CG-CB 4.44Å; F27-D137 WeakPolarHBondContact O-CB 3.42Å; D29-D137 HydrophobicContact CB-CB 4.39Å; D29-D137 VanDerWaalsContact CB-OD2 3.29Å; D29-D137 WeakPolarHBondContact CB-OD2 3.48Å; D29-D137 PolarHBondContact N-OD2 3.29Å; G119-D137 WeakPolarHBondContact O-CA 3.29Å; G119-D137 WeakPolarHBondContact O-CB 3.31Å; D137-L139 VanDerWaalsContact OD1-CB 3.23Å; D137-L139 WeakPolarHBondContact OD1-CB 3.47Å; D137-L139 PolarHBondContact OD1-N 3.38Å; D137-K165 PolarHBondContact O-NZ 2.9Å; D137-K165 IonicContact OD1-NZ 3.34Å; D137-K165 PolarHBondContact OD1-NZ 3.2Å
138D98.3Very high95.9Very high0 Ų029 Ų290%015%0.15CC..SBendtrans-95.418.1179.167.3-2.9000115.9R53 P54 Y117 G119 F121 L140 L162R53-D138 WeakPolarHBondContact CA-O 3.23Å; R53-D138 VanDerWaalsContact CD-OD1 3.26Å; R53-D138 WeakPolarHBondContact CD-OD1 3.48Å; R53-D138 WeakPolarHBondContact CG-OD1 3.4Å; R53-D138 IonicContact CZ-OD1 2.82Å; R53-D138 IonicContact NE-OD1 2.8Å; R53-D138 IonicContact NH1-OD1 2.94Å; R53-D138 PolarHBondContact NH1-OD1 2.83Å; P54-D138 WeakPolarHBondContact CD-O 3.36Å; P54-D138 HydrophobicContact CG-CB 4.34Å; Y117-D138 VanDerWaalsContact CE2-OD2 3.3Å; Y117-D138 WeakPolarHBondContact CE2-OD2 3.48Å; Y117-D138 VanDerWaalsContact CZ-OD2 3.32Å; Y117-D138 PolarHBondContact OH-OD1 3.48Å; Y117-D138 PolarHBondContact OH-OD2 3.27Å; G119-D138 PolarHBondContact O-N 2.79Å; F121-D138 HydrophobicContact CD2-CB 3.9Å; F121-D138 HydrophobicContact CE2-CB 3.6Å; D138-L140 PolarHBondContact O-N 2.78Å; D138-L162 HydrophobicContact CB-CD2 3.85Å
139L98.4Very high96Very high22 Ų2228 Ų2812%0.11515%0.146CC..  trans-69.1119.5168-69.6161.4000109.6A34 W51 R53 D137 K165A34-L139 HydrophobicContact CB-CD1 3.96Å; W51-L139 HydrophobicContact CB-CB 4.31Å; W51-L139 HydrophobicContact CB-CD2 4.39Å; W51-L139 HydrophobicContact CE3-CB 3.95Å; W51-L139 VanDerWaalsContact CE3-O 3.26Å; W51-L139 WeakPolarHBondContact CZ3-O 3.15Å; R53-L139 HydrophobicContact CG-CD2 3.6Å; R53-L139 HydrophobicContact CG-CG 4.06Å; D137-L139 VanDerWaalsContact OD1-CB 3.23Å; D137-L139 WeakPolarHBondContact OD1-CB 3.47Å; D137-L139 PolarHBondContact OD1-N 3.38Å; L139-K165 WeakPolarHBondContact O-CE 3.28Å; L139-K165 PolarHBondContact O-NZ 2.88Å
140L98.5Very high96.1Very high2 Ų227.5 Ų27.51%0.0114%0.14CC..EExtended strand (participates in β ladder)trans-113.1140.9-178.2-67.7170.5000111.3W51 K52 P54 D138 T142 L147 F158 A161 L162 K165W51-L140 WeakPolarHBondContact CA-O 3.35Å; K52-L140 PolarHBondContact N-O 2.86Å; K52-L140 PolarHBondContact O-N 2.86Å; P54-L140 HydrophobicContact CG-CD1 4.34Å; D138-L140 PolarHBondContact O-N 2.78Å; L140-T142 PolarHBondContact O-N 2.81Å; L140-L147 HydrophobicContact CB-CD2 3.51Å; L140-L147 HydrophobicContact CD1-CD2 3.79Å; L140-L147 HydrophobicContact CG-CD2 4.24Å; L140-F158 HydrophobicContact CD1-CD1 3.78Å; L140-F158 HydrophobicContact CD1-CE1 4.41Å; L140-A161 HydrophobicContact CD1-CB 3.81Å; L140-A161 HydrophobicContact CD2-CB 3.93Å; L140-L162 HydrophobicContact CD2-CD2 4.07Å; L140-L162 HydrophobicContact CG-CD2 4.45Å; L140-K165 HydrophobicContact CD2-CD 4.38Å
141P97.6Very high96.1Very high3 Ų326.6 Ų26.62%0.01914%0.136CC..EExtended strand (participates in β ladder)trans-65.2126.7176.2-25.137.5000112.4L39 V49 W51 I148 Y149 Y174L39-P141 HydrophobicContact CD2-CB 3.87Å; L39-P141 HydrophobicContact CD2-CG 3.61Å; V49-P141 HydrophobicContact CG1-CB 3.81Å; W51-P141 HydrophobicContact CD2-CG 4.36Å; W51-P141 HydrophobicContact CE3-CG 4.02Å; W51-P141 HydrophobicContact CH2-CG 3.79Å; W51-P141 HydrophobicContact CZ2-CG 4.12Å; W51-P141 HydrophobicContact CZ3-CG 3.73Å; P141-I148 HydrophobicContact CB-CD1 3.9Å; P141-I148 HydrophobicContact CB-CG1 3.95Å; P141-I148 PolarHBondContact O-N 2.83Å; P141-Y149 HydrophobicContact CB-CD2 3.84Å; P141-Y149 HydrophobicContact CB-CE2 3.68Å; P141-Y149 HydrophobicContact CG-CD2 3.83Å; P141-Y149 HydrophobicContact CG-CE2 3.7Å; P141-Y174 HydrophobicContact CG-CD2 4.42Å; P141-Y174 HydrophobicContact CG-CE2 3.77Å
142T97Very high95.9Very high0 Ų024.8 Ų24.80%013%0.131CC..EExtended strand (participates in β ladder)trans-131.8153.2178.569.70000113.2V49 E50 K52 L57 L140 K146 L147V49-T142 WeakPolarHBondContact CA-O 3.45Å; E50-T142 PolarHBondContact N-O 3.43Å; E50-T142 WeakPolarHBondContact O-CA 3.46Å; E50-T142 WeakPolarHBondContact O-CB 3.5Å; E50-T142 PolarHBondContact O-N 3.04Å; E50-T142 PolarHBondContact O-OG1 3.46Å; K52-T142 HydrophobicContact CB-CG2 4.23Å; L57-T142 HydrophobicContact CD1-CG2 4.1Å; L57-T142 HydrophobicContact CD2-CG2 4.03Å; L140-T142 PolarHBondContact O-N 2.81Å; T142-K146 CarbonylContact C-O 3.53Å; T142-K146 WeakPolarHBondContact CA-O 3.17Å; T142-K146 VanDerWaalsContact CB-O 3.26Å; T142-K146 WeakPolarHBondContact CB-O 3.07Å; T142-L147 HydrophobicContact CG2-CD2 4.09Å
143M95.1Very high95.4Very high24 Ų2429.7 Ų29.712%0.11816%0.157CC..EExtended strand (participates in β ladder)trans-129.1129.8165.2-75-176.5-69.700107.8P46 R47 V49 I77 G145 K146 I148P46-M143 HydrophobicContact CG-CE 4.4Å; P46-M143 HydrophobicContact CG-SD 4.36Å; R47-M143 HydrophobicContact CB-CG 4.4Å; R47-M143 HydrophobicContact CB-SD 3.72Å; R47-M143 HydrophobicContact CG-SD 4.44Å; V49-M143 HydrophobicContact CG2-CG 4.28Å; I77-M143 HydrophobicContact CD1-CE 3.75Å; M143-G145 PolarHBondContact O-N 3.18Å; M143-K146 PolarHBondContact N-O 3.07Å; M143-K146 PolarHBondContact O-N 2.92Å; M143-I148 HydrophobicContact CB-CG2 3.66Å; M143-I148 HydrophobicContact CE-CB 3.85Å; M143-I148 HydrophobicContact CE-CD1 4.14Å; M143-I148 HydrophobicContact CE-CG2 3.35Å; M143-I148 HydrophobicContact CG-CG2 3.75Å; M143-I148 HydrophobicContact SD-CG2 4.37Å
144D91.9Very high95Very high118 Ų11831.2 Ų31.263%0.63117%0.167SC*.THydrogen-bonded Turntrans53.137.2-179-54.3-44.9000113R47 K146R47-D144 IonicContact CZ-OD2 3.67Å; R47-D144 IonicContact NH1-OD2 3.84Å; R47-D144 PolarHBondContact NH1-OD2 2.87Å; D144-K146 VanDerWaalsContact C-N 3.29Å; D144-K146 PolarHBondContact O-N 2.82Å
145G91.1Very high94.7Very high37 Ų3740.1 Ų40.138%0.38121%0.206SC..THydrogen-bonded Turntrans73.113.2-179.400000115.2M143M143-G145 PolarHBondContact O-N 3.18Å
146K93.9Very high94.5Very high157 Ų15742 Ų4268%0.68322%0.216SC*.EExtended strand (participates in β ladder)trans-117.1140.7177.4-62.4-179.9-177.6178.10111.2T142 M143 D144T142-K146 CarbonylContact C-O 3.53Å; T142-K146 WeakPolarHBondContact CA-O 3.17Å; T142-K146 VanDerWaalsContact CB-O 3.26Å; T142-K146 WeakPolarHBondContact CB-O 3.07Å; M143-K146 PolarHBondContact N-O 3.07Å; M143-K146 PolarHBondContact O-N 2.92Å; D144-K146 VanDerWaalsContact C-N 3.29Å; D144-K146 PolarHBondContact O-N 2.82Å
147L95.7Very high94.3Very high38 Ų3842.2 Ų42.220%0.19922%0.217CC..EExtended strand (participates in β ladder)trans-59.5137.5171.2-66.2172.8000109.9L57 L140 T142 H151 F158 A161L57-L147 HydrophobicContact CD1-CD2 4.01Å; L57-L147 HydrophobicContact CD1-CG 4.35Å; L140-L147 HydrophobicContact CB-CD2 3.51Å; L140-L147 HydrophobicContact CD1-CD2 3.79Å; L140-L147 HydrophobicContact CG-CD2 4.24Å; T142-L147 HydrophobicContact CG2-CD2 4.09Å; L147-H151 HydrophobicContact CB-CB 4.13Å; L147-H151 HydrophobicContact CD1-CB 3.72Å; L147-F158 HydrophobicContact CD1-CD1 4.32Å; L147-F158 HydrophobicContact CD1-CE1 4.18Å; L147-A161 HydrophobicContact CD1-CB 4.31Å
148I94.5Very high94.2Very high8 Ų842.3 Ų42.34%0.04122%0.217CC..  trans-105.9-16.4-175.467.6177.7000112.9V49 G76 I77 P141 M143V49-I148 HydrophobicContact CG1-CD1 4.29Å; V49-I148 HydrophobicContact CG2-CD1 3.81Å; G76-I148 CarbonylContact C-O 3.52Å; G76-I148 VanDerWaalsContact CA-O 3.28Å; G76-I148 WeakPolarHBondContact CA-O 2.92Å; I77-I148 HydrophobicContact CD1-CB 4.18Å; I77-I148 HydrophobicContact CD1-CD1 4.2Å; I77-I148 HydrophobicContact CD1-CG1 4.44Å; I77-I148 HydrophobicContact CG1-CB 4.45Å; I77-I148 WeakPolarHBondContact CG1-O 3.34Å; I77-I148 PolarHBondContact N-O 3.27Å; P141-I148 HydrophobicContact CB-CD1 3.9Å; P141-I148 HydrophobicContact CB-CG1 3.95Å; P141-I148 PolarHBondContact O-N 2.83Å; M143-I148 HydrophobicContact CB-CG2 3.66Å; M143-I148 HydrophobicContact CE-CB 3.85Å; M143-I148 HydrophobicContact CE-CD1 4.14Å; M143-I148 HydrophobicContact CE-CG2 3.35Å; M143-I148 HydrophobicContact CG-CG2 3.75Å; M143-I148 HydrophobicContact SD-CG2 4.37Å
149Y94.8Very high94.1Very high14 Ų1442.5 Ų42.56%0.05522%0.218CC..SBendtrans-107.5-151.8176.2-57.1-61.8000110.7L39 G76 I77 L78 P141 H151 E164 Y174L39-Y149 HydrophobicContact CD2-CE2 3.85Å; G76-Y149 WeakPolarHBondContact CA-O 3.25Å; I77-Y149 HydrophobicContact CG1-CD1 4.38Å; I77-Y149 HydrophobicContact CG1-CE1 4.21Å; L78-Y149 HydrophobicContact CB-CD1 3.85Å; L78-Y149 HydrophobicContact CB-CE1 3.98Å; L78-Y149 HydrophobicContact CD2-CD1 4.38Å; L78-Y149 HydrophobicContact CD2-CE1 4.34Å; P141-Y149 HydrophobicContact CB-CD2 3.84Å; P141-Y149 HydrophobicContact CB-CE2 3.68Å; P141-Y149 HydrophobicContact CG-CD2 3.83Å; P141-Y149 HydrophobicContact CG-CE2 3.7Å; Y149-H151 PolarHBondContact O-N 3.03Å; Y149-H151 PolarHBondContact O-ND1 3.12Å; Y149-E164 WeakPolarHBondContact CB-OE2 3.48Å; Y149-Y174 HydrophobicContact CD1-CD1 4.11Å; Y149-Y174 AromaticContact CD2-CD1 3.39Å; Y149-Y174 HydrophobicContact CD2-CD1 3.39Å; Y149-Y174 HydrophobicContact CD2-CD2 4.32Å; Y149-Y174 AromaticContact CD2-CE1 3.35Å; Y149-Y174 HydrophobicContact CD2-CE1 3.35Å; Y149-Y174 HydrophobicContact CD2-CE2 4.29Å; Y149-Y174 AromaticContact CD2-CG 3.9Å; Y149-Y174 HydrophobicContact CD2-CG 3.9Å; Y149-Y174 AromaticContact CD2-CZ 3.82Å; Y149-Y174 HydrophobicContact CE1-CD1 4.21Å; Y149-Y174 HydrophobicContact CE1-CG 4.41Å; Y149-Y174 AromaticContact CE2-CD1 3.5Å; Y149-Y174 HydrophobicContact CE2-CD1 3.5Å; Y149-Y174 VanDerWaalsContact CE2-CD1 3.5Å; Y149-Y174 AromaticContact CE2-CD2 3.84Å; Y149-Y174 HydrophobicContact CE2-CD2 3.84Å; Y149-Y174 AromaticContact CE2-CE1 3.85Å; Y149-Y174 HydrophobicContact CE2-CE1 3.85Å; Y149-Y174 HydrophobicContact CE2-CE2 4.16Å; Y149-Y174 AromaticContact CE2-CG 3.48Å; Y149-Y174 HydrophobicContact CE2-CG 3.48Å; Y149-Y174 VanDerWaalsContact CE2-CG 3.48Å; Y149-Y174 AromaticContact CG-CD1 3.72Å; Y149-Y174 HydrophobicContact CG-CD1 3.72Å; Y149-Y174 AromaticContact CG-CE1 3.8Å; Y149-Y174 HydrophobicContact CG-CE1 3.8Å; Y149-Y174 AromaticContact CZ-CD1 3.91Å; Y149-Y174 AromaticContact CZ-CG 3.77Å
150C93.8Very high93.9Very high1 Ų141.5 Ų41.51%0.00721%0.213CC..SBendtrans-60.4134.2-176.2-167.90000111.9H74 A161 E164H74-C150 VanDerWaalsContact O-CA 3.28Å; H74-C150 WeakPolarHBondContact O-CA 3.46Å; H74-C150 PolarHBondContact O-SG 3.13Å; C150-A161 WeakPolarHBondContact O-CA 3.39Å; C150-A161 VanDerWaalsContact O-CB 3.29Å; C150-A161 WeakPolarHBondContact O-CB 3.46Å; C150-E164 WeakPolarHBondContact CA-OE2 3.4Å; C150-E164 HydrophobicContact CB-CB 4.13Å; C150-E164 HydrophobicContact CB-CG 4.28Å; C150-E164 WeakPolarHBondContact CB-OE1 3.24Å; C150-E164 WeakPolarHBondContact CB-OE2 3.4Å; C150-E164 PolarHBondContact N-OE1 3.05Å; C150-E164 PolarHBondContact N-OE2 2.96Å
151H92.6Very high93.8Very high56 Ų5641.5 Ų41.526%0.25921%0.213SC..BIsolated β-bridgetrans-154.2161.4-178.459.8-79.3000112.4D72 H74 L147 Y149D72-H151 CarbonylContact O-C 3.5Å; H74-H151 WeakPolarHBondContact CB-O 3.46Å; H74-H151 PolarHBondContact N-O 2.72Å; H74-H151 PolarHBondContact ND1-O 2.62Å; H74-H151 PolarHBondContact O-N 3Å; L147-H151 HydrophobicContact CB-CB 4.13Å; L147-H151 HydrophobicContact CD1-CB 3.72Å; Y149-H151 PolarHBondContact O-N 3.03Å; Y149-H151 PolarHBondContact O-ND1 3.12Å
152S91.6Very high93.8Very high9 Ų941.4 Ų41.46%0.06321%0.213CC..  trans-84.5153.6171.9-175.20000111.5D72 V154 E157D72-S152 WeakPolarHBondContact O-CA 3.37Å; D72-S152 PolarHBondContact O-N 2.93Å; S152-V154 PolarHBondContact OG-N 2.79Å; S152-E157 VanDerWaalsContact CB-OE2 3.29Å; S152-E157 WeakPolarHBondContact CB-OE2 3.34Å; S152-E157 PolarHBondContact OG-OE2 2.84Å
153N86.1Confident93.8Very high112 Ų11241.4 Ų41.460%0.59921%0.213SC*.SBendtrans-70.4-22.5165.8-80.9-15.5000111.5H74 K155H74-N153 PolarHBondContact CE1-ND2 2.8Å; H74-N153 PolarHBondContact CE1-OD1 3.26Å; H74-N153 VanDerWaalsContact CE1-OD1 3.22Å; H74-N153 PolarHBondContact ND1-OD1 2.82Å; H74-N153 PolarHBondContact NE2-ND2 3.01Å; H74-N153 PolarHBondContact NE2-OD1 2.87Å; N153-K155 PolarHBondContact O-N 2.77Å
154V90.6Very high94Very high52 Ų5240.3 Ų40.332%0.31521%0.207SC..SBendtrans-78109.4172.3-177.90000107.9V65 S152 N156 E157V65-V154 HydrophobicContact CB-CG1 4Å; V65-V154 HydrophobicContact CG1-CG1 4.01Å; V65-V154 HydrophobicContact CG2-CG1 3.95Å; S152-V154 PolarHBondContact OG-N 2.79Å; V154-N156 WeakPolarHBondContact CG1-OD1 3.45Å; V154-N156 PolarHBondContact O-N 2.87Å; V154-E157 HydrophobicContact CB-CB 4.03Å; V154-E157 HydrophobicContact CG1-CB 4.12Å; V154-E157 PolarHBondContact O-N 2.86Å; V154-E157 VanDerWaalsContact O-N 3.08Å
155K90.8Very high94.3Very high187 Ų18734.7 Ų34.781%0.81318%0.177SC*.THydrogen-bonded Turntrans-58.6-22.5-168.8-65.6-174.5179.3177.90115.1N153N153-K155 PolarHBondContact O-N 2.77Å
156N94.6Very high94.6Very high41 Ų4133 Ų3322%0.21916%0.159CC..THydrogen-bonded Turntrans-108.616.3-177.170.1-37.7000113.6C58 D60 H62 V154 F158C58-N156 HydrophobicContact CB-CB 4.36Å; D60-N156 VanDerWaalsContact O-CB 3.25Å; D60-N156 WeakPolarHBondContact O-CB 3.33Å; D60-N156 PolarHBondContact O-ND2 2.96Å; H62-N156 PolarHBondContact CD2-ND2 3.39Å; H62-N156 PolarHBondContact N-O 3.38Å; V154-N156 WeakPolarHBondContact CG1-OD1 3.45Å; V154-N156 PolarHBondContact O-N 2.87Å; N156-F158 VanDerWaalsContact C-CE2 3.44Å; N156-F158 WeakPolarHBondContact O-CD2 3.41Å; N156-F158 WeakPolarHBondContact O-CE2 3.36Å
157E95.6Very high94.8Very high4 Ų425.5 Ų25.52%0.01913%0.127CC..BIsolated β-bridgetrans-110130.2177.6-175.6177.5-129.300111.9H62 V65 D72 S152 V154H62-E157 WeakPolarHBondContact O-CA 3.29Å; V65-E157 HydrophobicContact CB-CB 4.36Å; V65-E157 HydrophobicContact CG2-CB 3.86Å; V65-E157 HydrophobicContact CG2-CG 4.31Å; V65-E157 PolarHBondContact N-OE1 2.94Å; D72-E157 VanDerWaalsContact CB-OE2 3.26Å; D72-E157 WeakPolarHBondContact CB-OE2 3.49Å; S152-E157 VanDerWaalsContact CB-OE2 3.29Å; S152-E157 WeakPolarHBondContact CB-OE2 3.34Å; S152-E157 PolarHBondContact OG-OE2 2.84Å; V154-E157 HydrophobicContact CB-CB 4.03Å; V154-E157 HydrophobicContact CG1-CB 4.12Å; V154-E157 PolarHBondContact O-N 2.86Å; V154-E157 VanDerWaalsContact O-N 3.08Å
158F96.6Very high94.9Very high4 Ų423.7 Ų23.72%0.01812%0.117CC..  trans-128.80.2-166.8-65-86.4000116.6P54 L57 C58 P61 H62 W109 L140 L147 N156 S160 A161 L162P54-F158 HydrophobicContact CB-CD1 4.05Å; P54-F158 HydrophobicContact CB-CD2 3.79Å; P54-F158 HydrophobicContact CB-CE1 3.97Å; P54-F158 HydrophobicContact CB-CE2 3.72Å; P54-F158 HydrophobicContact CB-CG 3.96Å; P54-F158 HydrophobicContact CB-CZ 3.81Å; P54-F158 HydrophobicContact CG-CB 4.34Å; P54-F158 HydrophobicContact CG-CD1 3.8Å; P54-F158 HydrophobicContact CG-CD2 4.18Å; P54-F158 HydrophobicContact CG-CE1 4.12Å; P54-F158 HydrophobicContact CG-CE2 4.47Å; P54-F158 HydrophobicContact CG-CG 3.83Å; P54-F158 HydrophobicContact CG-CZ 4.45Å; L57-F158 HydrophobicContact CB-CZ 4.49Å; L57-F158 HydrophobicContact CD1-CE1 4.17Å; C58-F158 VanDerWaalsContact SG-CE2 3.55Å; P61-F158 HydrophobicContact CB-CD2 3.99Å; P61-F158 HydrophobicContact CB-CE2 3.71Å; H62-F158 PolarHBondContact O-N 2.87Å; W109-F158 HydrophobicContact CH2-CB 4.17Å; W109-F158 HydrophobicContact CZ3-CB 4.42Å; L140-F158 HydrophobicContact CD1-CD1 3.78Å; L140-F158 HydrophobicContact CD1-CE1 4.41Å; L147-F158 HydrophobicContact CD1-CD1 4.32Å; L147-F158 HydrophobicContact CD1-CE1 4.18Å; N156-F158 VanDerWaalsContact C-CE2 3.44Å; N156-F158 WeakPolarHBondContact O-CD2 3.41Å; N156-F158 WeakPolarHBondContact O-CE2 3.36Å; F158-S160 VanDerWaalsContact C-N 3.29Å; F158-S160 PolarHBondContact O-N 3.35Å; F158-A161 PolarHBondContact O-N 2.81Å; F158-L162 HydrophobicContact CB-CD1 4.38Å; F158-L162 WeakPolarHBondContact O-CG 3.27Å; F158-L162 PolarHBondContact O-N 3.16Å; F158-L162 VanDerWaalsContact O-N 3.11Å
159W94.8Very high95.1Very high3 Ų323.5 Ų23.51%0.01112%0.116CC..Hα-helixtrans-58.2-39.4-178.271.6-92.5000113.2L63 F64 I68 D72 L73 I101 L162 L163L63-W159 HydrophobicContact CD1-CB 3.95Å; L63-W159 HydrophobicContact CG-CB 4.11Å; L63-W159 WeakPolarHBondContact O-CB 3.32Å; L63-W159 VanDerWaalsContact O-CD1 3.23Å; L63-W159 PolarHBondContact O-N 2.9Å; L63-W159 VanDerWaalsContact O-N 3.13Å; F64-W159 HydrophobicContact CD1-CB 3.95Å; F64-W159 AromaticContact CD1-CD1 3.54Å; F64-W159 HydrophobicContact CD1-CD2 4.5Å; F64-W159 AromaticContact CD1-CG 3.73Å; F64-W159 HydrophobicContact CD1-CG 3.73Å; F64-W159 HydrophobicContact CE1-CB 3.44Å; F64-W159 VanDerWaalsContact CE1-CB 3.44Å; F64-W159 AromaticContact CE1-CD1 3.79Å; F64-W159 HydrophobicContact CE1-CD2 4.05Å; F64-W159 AromaticContact CE1-CG 3.47Å; F64-W159 HydrophobicContact CE1-CG 3.47Å; F64-W159 VanDerWaalsContact CE1-CG 3.47Å; F64-W159 HydrophobicContact CZ-CB 3.93Å; F64-W159 HydrophobicContact CZ-CG 4.42Å; I68-W159 HydrophobicContact CD1-CD2 4.5Å; I68-W159 HydrophobicContact CG2-CH2 3.9Å; I68-W159 HydrophobicContact CG2-CZ2 3.63Å; D72-W159 HydrophobicContact CB-CZ2 3.88Å; D72-W159 PolarHBondContact OD2-NE1 2.77Å; L73-W159 HydrophobicContact CD1-CH2 3.91Å; L73-W159 HydrophobicContact CD1-CZ2 4.4Å; L73-W159 HydrophobicContact CD2-CH2 3.7Å; L73-W159 HydrophobicContact CD2-CZ2 4.18Å; L73-W159 HydrophobicContact CD2-CZ3 4.23Å; L73-W159 HydrophobicContact CG-CH2 3.84Å; L73-W159 HydrophobicContact CG-CZ2 4.04Å; I101-W159 HydrophobicContact CD1-CB 4.45Å; I101-W159 HydrophobicContact CD1-CE3 3.98Å; W159-L162 PolarHBondContact O-N 3.37Å; W159-L163 HydrophobicContact CE3-CD2 4.21Å; W159-L163 HydrophobicContact CZ3-CD2 3.81Å; W159-L163 WeakPolarHBondContact O-CB 3.48Å; W159-L163 PolarHBondContact O-N 3.01Å
160S94.1Very high95.1Very high1 Ų124.4 Ų24.41%0.00712%0.122CC..Hα-helixtrans-66.8-43.6-177.451.20000112D72 F158 L163 E164D72-S160 PolarHBondContact O-OG 3.08Å; D72-S160 VanDerWaalsContact O-OG 3.07Å; F158-S160 VanDerWaalsContact C-N 3.29Å; F158-S160 PolarHBondContact O-N 3.35Å; S160-L163 PolarHBondContact O-N 3.41Å; S160-E164 WeakPolarHBondContact O-CB 3.3Å; S160-E164 PolarHBondContact O-N 3.42Å
161A96.9Very high95.2Very high3 Ų324.5 Ų24.53%0.02512%0.123CC..Hα-helixtrans-64-42.5176.900000112.1L140 L147 C150 F158 K165L140-A161 HydrophobicContact CD1-CB 3.81Å; L140-A161 HydrophobicContact CD2-CB 3.93Å; L147-A161 HydrophobicContact CD1-CB 4.31Å; C150-A161 WeakPolarHBondContact O-CA 3.39Å; C150-A161 VanDerWaalsContact O-CB 3.29Å; C150-A161 WeakPolarHBondContact O-CB 3.46Å; F158-A161 PolarHBondContact O-N 2.81Å; A161-K165 PolarHBondContact O-N 2.8Å
162L98Very high95.3Very high0 Ų023.8 Ų23.80%013%0.13CC..Hα-helixtrans-72-37.1179-68.2171000112.4L63 W109 F121 F123 D138 L140 F158 W159 K165 A166L63-L162 HydrophobicContact CD1-CD1 3.76Å; W109-L162 HydrophobicContact CH2-CD1 4.07Å; F121-L162 HydrophobicContact CD1-CD1 4Å; F121-L162 HydrophobicContact CD2-CD1 3.97Å; F121-L162 HydrophobicContact CD2-CD2 4.49Å; F121-L162 HydrophobicContact CE1-CD1 4.11Å; F121-L162 HydrophobicContact CE2-CD1 4.12Å; F121-L162 HydrophobicContact CG-CD1 3.94Å; F121-L162 HydrophobicContact CZ-CD1 4.19Å; F123-L162 HydrophobicContact CE2-CB 3.91Å; F123-L162 WeakPolarHBondContact CE2-O 3.45Å; F123-L162 HydrophobicContact CZ-CB 3.59Å; D138-L162 HydrophobicContact CB-CD2 3.85Å; L140-L162 HydrophobicContact CD2-CD2 4.07Å; L140-L162 HydrophobicContact CG-CD2 4.45Å; F158-L162 HydrophobicContact CB-CD1 4.38Å; F158-L162 WeakPolarHBondContact O-CG 3.27Å; F158-L162 PolarHBondContact O-N 3.16Å; F158-L162 VanDerWaalsContact O-N 3.11Å; W159-L162 PolarHBondContact O-N 3.37Å; L162-K165 WeakPolarHBondContact O-CB 3.45Å; L162-K165 PolarHBondContact O-N 3.11Å; L162-A166 PolarHBondContact O-N 2.85Å
163L97.4Very high95.5Very high0 Ų023.6 Ų23.60%013%0.129CC..Hα-helixtrans-62.7-45.2174.9179.165.9000111F83 V100 F123 F125 W159 S160 K165 A166 Y167F83-L163 HydrophobicContact CZ-CG 4.26Å; V100-L163 HydrophobicContact CG1-CD1 3.57Å; F123-L163 HydrophobicContact CB-CD1 4.4Å; F123-L163 HydrophobicContact CD1-CB 4.27Å; F123-L163 HydrophobicContact CD1-CD1 3.5Å; F123-L163 HydrophobicContact CE1-CB 3.95Å; F123-L163 HydrophobicContact CE1-CD1 4.04Å; F123-L163 HydrophobicContact CG-CD1 4.11Å; F123-L163 HydrophobicContact CZ-CB 4.45Å; F125-L163 HydrophobicContact CE1-CD1 3.76Å; F125-L163 HydrophobicContact CZ-CD1 3.73Å; W159-L163 HydrophobicContact CE3-CD2 4.21Å; W159-L163 HydrophobicContact CZ3-CD2 3.81Å; W159-L163 WeakPolarHBondContact O-CB 3.48Å; W159-L163 PolarHBondContact O-N 3.01Å; S160-L163 PolarHBondContact O-N 3.41Å; L163-K165 VanDerWaalsContact C-N 3.35Å; L163-A166 PolarHBondContact O-N 3.31Å; L163-Y167 PolarHBondContact O-N 2.91Å
164E97.9Very high96Very high1 Ų118.3 Ų18.31%0.00510%0.101CC..Hα-helixtrans-61.5-42.8174.8-172.7-173.1-138.100111.6N80 F83 Y149 C150 S160 A166 Y167 A168 Y174 L177N80-E164 PolarHBondContact ND2-OE1 3.18Å; F83-E164 HydrophobicContact CD1-CG 4.3Å; F83-E164 HydrophobicContact CE1-CB 3.67Å; F83-E164 HydrophobicContact CE1-CG 3.8Å; F83-E164 HydrophobicContact CZ-CB 4Å; F83-E164 HydrophobicContact CZ-CG 4.34Å; Y149-E164 WeakPolarHBondContact CB-OE2 3.48Å; C150-E164 WeakPolarHBondContact CA-OE2 3.4Å; C150-E164 HydrophobicContact CB-CB 4.13Å; C150-E164 HydrophobicContact CB-CG 4.28Å; C150-E164 WeakPolarHBondContact CB-OE1 3.24Å; C150-E164 WeakPolarHBondContact CB-OE2 3.4Å; C150-E164 PolarHBondContact N-OE1 3.05Å; C150-E164 PolarHBondContact N-OE2 2.96Å; S160-E164 WeakPolarHBondContact O-CB 3.3Å; S160-E164 PolarHBondContact O-N 3.42Å; E164-A166 VanDerWaalsContact C-N 3.35Å; E164-A166 PolarHBondContact O-N 2.68Å; E164-Y167 CarbonylContact O-C 3.55Å; E164-Y167 PolarHBondContact O-N 3.16Å; E164-Y167 VanDerWaalsContact O-N 3.16Å; E164-A168 WeakPolarHBondContact O-CB 3.32Å; E164-A168 PolarHBondContact O-N 2.93Å; E164-Y174 HydrophobicContact CG-CE1 4.1Å; E164-L177 HydrophobicContact CG-CD1 4.23Å
165K98.5Very high96.2Very high1 Ų116.7 Ų16.70%0.0049%0.09CC..Hα-helixtrans-57.4-46.8174.9-173.6178.2173.9179.70112.1F32 V136 D137 L139 L140 A161 L162 L163 Y167 A168 K169 Y174F32-K165 HydrophobicContact CD1-CG 4.32Å; F32-K165 HydrophobicContact CE1-CG 4.13Å; V136-K165 HydrophobicContact CB-CD 4.37Å; V136-K165 HydrophobicContact CG1-CG 4.36Å; D137-K165 PolarHBondContact O-NZ 2.9Å; D137-K165 IonicContact OD1-NZ 3.34Å; D137-K165 PolarHBondContact OD1-NZ 3.2Å; L139-K165 WeakPolarHBondContact O-CE 3.28Å; L139-K165 PolarHBondContact O-NZ 2.88Å; L140-K165 HydrophobicContact CD2-CD 4.38Å; A161-K165 PolarHBondContact O-N 2.8Å; L162-K165 WeakPolarHBondContact O-CB 3.45Å; L162-K165 PolarHBondContact O-N 3.11Å; L163-K165 VanDerWaalsContact C-N 3.35Å; K165-Y167 VanDerWaalsContact C-N 3.27Å; K165-Y167 PolarHBondContact O-N 3.41Å; K165-A168 PolarHBondContact O-N 2.93Å; K165-K169 WeakPolarHBondContact O-CB 3.25Å; K165-K169 PolarHBondContact O-N 2.79Å; K165-Y174 WeakPolarHBondContact CA-OH 3.44Å; K165-Y174 VanDerWaalsContact CB-OH 3.23Å; K165-Y174 WeakPolarHBondContact CB-OH 3.47Å; K165-Y174 HydrophobicContact CG-CE2 4.49Å
166A98.4Very high96.4Very high0 Ų07.9 Ų7.90%05%0.052CC..Hα-helixtrans-63.4-36.217800000112F123 F125 V134 V136 L162 L163 E164 K169 L170F123-A166 HydrophobicContact CB-CB 4.03Å; F123-A166 HydrophobicContact CD2-CB 3.4Å; F123-A166 HydrophobicContact CE2-CB 4.14Å; F123-A166 HydrophobicContact CG-CB 3.91Å; F125-A166 HydrophobicContact CE2-CB 3.88Å; F125-A166 HydrophobicContact CZ-CB 4.02Å; V134-A166 HydrophobicContact CB-CB 4.47Å; V134-A166 HydrophobicContact CG1-CB 4.11Å; V136-A166 HydrophobicContact CG1-CB 3.86Å; V136-A166 HydrophobicContact CG2-CB 4.35Å; L162-A166 PolarHBondContact O-N 2.85Å; L163-A166 PolarHBondContact O-N 3.31Å; E164-A166 VanDerWaalsContact C-N 3.35Å; E164-A166 PolarHBondContact O-N 2.68Å; A166-K169 PolarHBondContact O-N 3.1Å; A166-L170 PolarHBondContact O-N 2.95Å; A166-L170 VanDerWaalsContact O-N 3.14Å
167Y97.7Very high96.3Very high1 Ų16 Ų60%0.0044%0.041CC..Hα-helixtrans-72.4-36.7175.7-159.4-116.8000112.8W82 F83 F125 L163 E164 K165 K169 L170 A171 L177 D188 F189 R411W82-Y167 AromaticContact CH2-CE1 3.61Å; W82-Y167 HydrophobicContact CH2-CE1 3.61Å; W82-Y167 HydrophobicContact CZ2-CE1 4.37Å; W82-Y167 HydrophobicContact CZ3-CE1 4.14Å; F83-Y167 AromaticContact CD2-CD1 3.32Å; F83-Y167 HydrophobicContact CD2-CD1 3.32Å; F83-Y167 AromaticContact CD2-CE1 3.55Å; F83-Y167 HydrophobicContact CD2-CE1 3.55Å; F83-Y167 HydrophobicContact CD2-CG 4.02Å; F83-Y167 AromaticContact CE2-CD1 3.37Å; F83-Y167 HydrophobicContact CE2-CD1 3.37Å; F83-Y167 HydrophobicContact CE2-CD2 4.35Å; F83-Y167 AromaticContact CE2-CE1 3.98Å; F83-Y167 HydrophobicContact CE2-CE1 3.98Å; F83-Y167 AromaticContact CE2-CG 3.57Å; F83-Y167 HydrophobicContact CE2-CG 3.57Å; F83-Y167 HydrophobicContact CG-CD1 4.35Å; F83-Y167 HydrophobicContact CZ-CD1 4.45Å; F125-Y167 AromaticContact CD1-CD2 3.74Å; F125-Y167 HydrophobicContact CD1-CD2 3.74Å; F125-Y167 HydrophobicContact CD1-CE2 4.16Å; F125-Y167 AromaticContact CE1-CD2 3.61Å; F125-Y167 HydrophobicContact CE1-CD2 3.61Å; F125-Y167 HydrophobicContact CE1-CE2 4.41Å; F125-Y167 HydrophobicContact CE1-CG 4.34Å; F125-Y167 HydrophobicContact CG-CD2 4.34Å; F125-Y167 HydrophobicContact CZ-CD2 4.07Å; L163-Y167 PolarHBondContact O-N 2.91Å; E164-Y167 CarbonylContact O-C 3.55Å; E164-Y167 PolarHBondContact O-N 3.16Å; E164-Y167 VanDerWaalsContact O-N 3.16Å; K165-Y167 VanDerWaalsContact C-N 3.27Å; K165-Y167 PolarHBondContact O-N 3.41Å; Y167-K169 VanDerWaalsContact C-N 3.34Å; Y167-L170 HydrophobicContact CD2-CD1 4.39Å; Y167-L170 WeakPolarHBondContact O-CB 3.4Å; Y167-L170 PolarHBondContact O-N 2.85Å; Y167-A171 PolarHBondContact O-N 3.11Å; Y167-L177 HydrophobicContact CD1-CD1 4.16Å; Y167-L177 HydrophobicContact CD1-CD2 3.58Å; Y167-L177 HydrophobicContact CE1-CD2 3.94Å; Y167-D188 HydrophobicContact CE2-CB 4.01Å; Y167-D188 PolarHBondContact OH-OD2 2.94Å; Y167-F189 HydrophobicContact CE2-CE1 4.5Å; Y167-R411 VanDerWaalsContact CZ-NH2 3.35Å; Y167-R411 PolarHBondContact OH-NH1 2.81Å; Y167-R411 PolarHBondContact OH-NH2 2.87Å
168A97.7Very high96.1Very high0 Ų09.6 Ų9.60%06%0.061CC..Hα-helixtrans-62.7-41.7172.200000111.1F32 E164 K165 L170 A171 G172 S173 Y174 L177F32-A168 HydrophobicContact CZ-CB 4.05Å; E164-A168 WeakPolarHBondContact O-CB 3.32Å; E164-A168 PolarHBondContact O-N 2.93Å; K165-A168 PolarHBondContact O-N 2.93Å; A168-L170 PolarHBondContact O-N 2.88Å; A168-A171 CarbonylContact O-C 3.45Å; A168-A171 WeakPolarHBondContact O-CA 3.13Å; A168-A171 PolarHBondContact O-N 2.85Å; A168-A171 VanDerWaalsContact O-N 3.1Å; A168-G172 CarbonylContact O-C 3.6Å; A168-G172 PolarHBondContact O-N 3.34Å; A168-S173 PolarHBondContact O-N 2.87Å; A168-S173 VanDerWaalsContact O-N 3.08Å; A168-Y174 HydrophobicContact CB-CD1 3.94Å; A168-Y174 HydrophobicContact CB-CD2 4.08Å; A168-Y174 HydrophobicContact CB-CE1 4.17Å; A168-Y174 HydrophobicContact CB-CE2 4.3Å; A168-Y174 HydrophobicContact CB-CG 3.91Å; A168-L177 HydrophobicContact CB-CD1 3.83Å; A168-L177 HydrophobicContact CB-CG 4.36Å
169K97.9Very high95.6Very high4 Ų411.4 Ų11.42%0.0178%0.081CC..Hα-helixtrans-58.4-44.6172.9175.9173.5-177.81770112.5F8 D29 F32 V134 V135 V136 K165 A166 Y167 A171 G172F8-K169 HydrophobicContact CD1-CD 4.44Å; F8-K169 HydrophobicContact CD1-CG 4.36Å; F8-K169 HydrophobicContact CE1-CD 4.24Å; F8-K169 HydrophobicContact CE1-CG 3.76Å; D29-K169 IonicContact OD1-NZ 2.66Å; D29-K169 PolarHBondContact OD1-NZ 3.28Å; D29-K169 WeakPolarHBondContact OD2-CE 3.41Å; D29-K169 IonicContact OD2-NZ 3.77Å; D29-K169 PolarHBondContact OD2-NZ 2.82Å; F32-K169 HydrophobicContact CB-CB 4.16Å; F32-K169 HydrophobicContact CB-CD 3.66Å; F32-K169 HydrophobicContact CB-CG 3.8Å; F32-K169 HydrophobicContact CD1-CB 4.15Å; F32-K169 HydrophobicContact CD2-CB 3.76Å; F32-K169 HydrophobicContact CD2-CG 3.95Å; F32-K169 HydrophobicContact CE1-CB 4.48Å; F32-K169 HydrophobicContact CE2-CB 4.14Å; F32-K169 HydrophobicContact CG-CB 3.75Å; F32-K169 HydrophobicContact CG-CD 4.21Å; F32-K169 HydrophobicContact CG-CG 3.92Å; F32-K169 HydrophobicContact CZ-CB 4.48Å; V134-K169 HydrophobicContact CG1-CB 4.5Å; V134-K169 HydrophobicContact CG1-CD 3.92Å; V134-K169 HydrophobicContact CG1-CG 4.29Å; V135-K169 PolarHBondContact O-NZ 2.83Å; V136-K169 HydrophobicContact CG1-CD 3.95Å; K165-K169 WeakPolarHBondContact O-CB 3.25Å; K165-K169 PolarHBondContact O-N 2.79Å; A166-K169 PolarHBondContact O-N 3.1Å; Y167-K169 VanDerWaalsContact C-N 3.34Å; K169-A171 VanDerWaalsContact C-N 3.29Å; K169-A171 PolarHBondContact O-N 3.33Å; K169-G172 PolarHBondContact O-N 2.92Å
170L95.5Very high95.3Very high33 Ų3313.5 Ų13.517%0.17310%0.103CC..Hα-helixtrans-61.2-38.3173.4-78.5179.4000112.8F8 F125 V134 A166 Y167 A168 G172F8-L170 HydrophobicContact CD1-CD2 4.46Å; F8-L170 HydrophobicContact CD2-CD2 3.51Å; F8-L170 HydrophobicContact CE2-CD2 3.68Å; F8-L170 HydrophobicContact CG-CD2 3.93Å; F8-L170 HydrophobicContact CZ-CD2 4.22Å; F125-L170 HydrophobicContact CB-CD1 3.77Å; F125-L170 HydrophobicContact CD1-CD1 4.49Å; F125-L170 HydrophobicContact CD2-CD1 3.2Å; F125-L170 HydrophobicContact CD2-CG 4.29Å; F125-L170 HydrophobicContact CE2-CD1 3.81Å; F125-L170 HydrophobicContact CG-CD1 3.57Å; V134-L170 HydrophobicContact CG1-CG 4.46Å; V134-L170 HydrophobicContact CG2-CD1 3.79Å; V134-L170 HydrophobicContact CG2-CD2 3.48Å; V134-L170 VanDerWaalsContact CG2-CD2 3.48Å; V134-L170 HydrophobicContact CG2-CG 3.57Å; A166-L170 PolarHBondContact O-N 2.95Å; A166-L170 VanDerWaalsContact O-N 3.14Å; Y167-L170 HydrophobicContact CD2-CD1 4.39Å; Y167-L170 WeakPolarHBondContact O-CB 3.4Å; Y167-L170 PolarHBondContact O-N 2.85Å; A168-L170 PolarHBondContact O-N 2.88Å; L170-G172 VanDerWaalsContact C-N 3.29Å
171A95.1Very high95.1Very high3 Ų315.2 Ų15.23%0.02512%0.116CC..Hα-helixtrans-79.9-8.9178.400000113.5Y167 A168 K169 A176 L177 R411 R412Y167-A171 PolarHBondContact O-N 3.11Å; A168-A171 CarbonylContact O-C 3.45Å; A168-A171 WeakPolarHBondContact O-CA 3.13Å; A168-A171 PolarHBondContact O-N 2.85Å; A168-A171 VanDerWaalsContact O-N 3.1Å; K169-A171 VanDerWaalsContact C-N 3.29Å; K169-A171 PolarHBondContact O-N 3.33Å; A171-A176 HydrophobicContact CB-CB 3.88Å; A171-A176 VanDerWaalsContact O-CB 3.23Å; A171-A176 WeakPolarHBondContact O-CB 3.3Å; A171-L177 HydrophobicContact CB-CD2 3.53Å; A171-L177 HydrophobicContact CB-CG 4.4Å; A171-R411 HydrophobicContact CB-CB 4.25Å; A171-R411 CarbonylContact O-C 3.52Å; A171-R412 WeakPolarHBondContact O-CA 3.45Å; A171-R412 PolarHBondContact O-N 3.1Å
172G95Very high94.9Very high41 Ų4115.3 Ų15.342%0.42312%0.116SC..THydrogen-bonded Turntrans94.7-22.9178.800000115.6A168 K169 L170A168-G172 CarbonylContact O-C 3.6Å; A168-G172 PolarHBondContact O-N 3.34Å; K169-G172 PolarHBondContact O-N 2.92Å; L170-G172 VanDerWaalsContact C-N 3.29Å
173S96Very high94.7Very high5 Ų515.5 Ų15.54%0.03512%0.118CC..SBendtrans-166.6167.2174.457.10000110.5S38 Y41 A168 A176S38-S173 CarbonylContact O-C 3.52Å; S38-S173 VanDerWaalsContact O-CA 3.27Å; S38-S173 WeakPolarHBondContact O-CA 3.45Å; S38-S173 WeakPolarHBondContact O-CB 3.44Å; Y41-S173 WeakPolarHBondContact CD1-OG 3.33Å; Y41-S173 WeakPolarHBondContact CE1-OG 3.42Å; A168-S173 PolarHBondContact O-N 2.87Å; A168-S173 VanDerWaalsContact O-N 3.08Å; S173-A176 WeakPolarHBondContact O-CB 3.29Å; S173-A176 PolarHBondContact O-N 3.28Å; S173-A176 PolarHBondContact OG-N 3.02Å
174Y96.6Very high94.6Very high1 Ų116.5 Ų16.50%0.00412%0.123CC..SBendtrans-61.9-46170.7-82.1-88.2000111.8F32 S38 L39 W51 L78 P141 Y149 E164 K165 A168 A176 L177F32-Y174 HydrophobicContact CE1-CD2 4.34Å; F32-Y174 HydrophobicContact CE1-CE2 4.01Å; F32-Y174 HydrophobicContact CZ-CD2 4.18Å; F32-Y174 HydrophobicContact CZ-CE2 4.3Å; S38-Y174 WeakPolarHBondContact O-CD2 3.41Å; S38-Y174 PolarHBondContact O-N 3.34Å; L39-Y174 HydrophobicContact CD2-CD2 4.04Å; W51-Y174 HydrophobicContact CH2-CE2 4.2Å; L78-Y174 VanDerWaalsContact CD2-O 3.25Å; L78-Y174 WeakPolarHBondContact CD2-O 3.45Å; P141-Y174 HydrophobicContact CG-CD2 4.42Å; P141-Y174 HydrophobicContact CG-CE2 3.77Å; Y149-Y174 HydrophobicContact CD1-CD1 4.11Å; Y149-Y174 AromaticContact CD2-CD1 3.39Å; Y149-Y174 HydrophobicContact CD2-CD1 3.39Å; Y149-Y174 HydrophobicContact CD2-CD2 4.32Å; Y149-Y174 AromaticContact CD2-CE1 3.35Å; Y149-Y174 HydrophobicContact CD2-CE1 3.35Å; Y149-Y174 HydrophobicContact CD2-CE2 4.29Å; Y149-Y174 AromaticContact CD2-CG 3.9Å; Y149-Y174 HydrophobicContact CD2-CG 3.9Å; Y149-Y174 AromaticContact CD2-CZ 3.82Å; Y149-Y174 HydrophobicContact CE1-CD1 4.21Å; Y149-Y174 HydrophobicContact CE1-CG 4.41Å; Y149-Y174 AromaticContact CE2-CD1 3.5Å; Y149-Y174 HydrophobicContact CE2-CD1 3.5Å; Y149-Y174 VanDerWaalsContact CE2-CD1 3.5Å; Y149-Y174 AromaticContact CE2-CD2 3.84Å; Y149-Y174 HydrophobicContact CE2-CD2 3.84Å; Y149-Y174 AromaticContact CE2-CE1 3.85Å; Y149-Y174 HydrophobicContact CE2-CE1 3.85Å; Y149-Y174 HydrophobicContact CE2-CE2 4.16Å; Y149-Y174 AromaticContact CE2-CG 3.48Å; Y149-Y174 HydrophobicContact CE2-CG 3.48Å; Y149-Y174 VanDerWaalsContact CE2-CG 3.48Å; Y149-Y174 AromaticContact CG-CD1 3.72Å; Y149-Y174 HydrophobicContact CG-CD1 3.72Å; Y149-Y174 AromaticContact CG-CE1 3.8Å; Y149-Y174 HydrophobicContact CG-CE1 3.8Å; Y149-Y174 AromaticContact CZ-CD1 3.91Å; Y149-Y174 AromaticContact CZ-CG 3.77Å; E164-Y174 HydrophobicContact CG-CE1 4.1Å; K165-Y174 WeakPolarHBondContact CA-OH 3.44Å; K165-Y174 VanDerWaalsContact CB-OH 3.23Å; K165-Y174 WeakPolarHBondContact CB-OH 3.47Å; K165-Y174 HydrophobicContact CG-CE2 4.49Å; A168-Y174 HydrophobicContact CB-CD1 3.94Å; A168-Y174 HydrophobicContact CB-CD2 4.08Å; A168-Y174 HydrophobicContact CB-CE1 4.17Å; A168-Y174 HydrophobicContact CB-CE2 4.3Å; A168-Y174 HydrophobicContact CB-CG 3.91Å; Y174-A176 PolarHBondContact O-N 3.08Å; Y174-A176 VanDerWaalsContact O-N 3.11Å; Y174-L177 WeakPolarHBondContact O-CB 3.28Å; Y174-L177 PolarHBondContact O-N 2.85Å
175E95.1Very high94.4Very high18 Ų1816.5 Ų16.58%0.08412%0.123CC..G310 helixtrans-59.2-24.7177.6-172.8175.3-149.800112.9L39 F40 Y41 T42 R43 L177 D178L39-E175 WeakPolarHBondContact O-CB 3.31Å; L39-E175 PolarHBondContact O-N 2.82Å; F40-E175 VanDerWaalsContact CA-OE2 3.22Å; F40-E175 WeakPolarHBondContact CA-OE2 3.22Å; F40-E175 HydrophobicContact CB-CB 4.24Å; F40-E175 VanDerWaalsContact CB-OE2 3.27Å; F40-E175 WeakPolarHBondContact CB-OE2 3.29Å; Y41-E175 HydrophobicContact CD1-CB 4.28Å; Y41-E175 HydrophobicContact CE1-CB 3.84Å; Y41-E175 HydrophobicContact CE1-CG 3.94Å; Y41-E175 PolarHBondContact N-OE2 3.4Å; T42-E175 PolarHBondContact N-OE2 2.91Å; T42-E175 PolarHBondContact OG1-OE1 3.16Å; T42-E175 PolarHBondContact OG1-OE2 3.38Å; R43-E175 WeakPolarHBondContact CB-OE1 3.36Å; R43-E175 PolarHBondContact N-OE1 3.28Å; E175-L177 PolarHBondContact O-N 3.3Å; E175-D178 VanDerWaalsContact O-CB 3.3Å; E175-D178 WeakPolarHBondContact O-CB 3.36Å; E175-D178 PolarHBondContact O-N 2.79Å; E175-D178 VanDerWaalsContact O-N 3.08Å
176A94.1Very high94.3Very high2 Ų216.4 Ų16.42%0.01712%0.123CC..G310 helixtrans-65.8-18.7174.200000113.4Y41 A171 S173 Y174 K414Y41-A176 HydrophobicContact CE1-CB 4.39Å; A171-A176 HydrophobicContact CB-CB 3.88Å; A171-A176 VanDerWaalsContact O-CB 3.23Å; A171-A176 WeakPolarHBondContact O-CB 3.3Å; S173-A176 WeakPolarHBondContact O-CB 3.29Å; S173-A176 PolarHBondContact O-N 3.28Å; S173-A176 PolarHBondContact OG-N 3.02Å; Y174-A176 PolarHBondContact O-N 3.08Å; Y174-A176 VanDerWaalsContact O-N 3.11Å; A176-K414 HydrophobicContact CB-CD 4.42Å; A176-K414 PolarHBondContact O-NZ 3.22Å
177L94.3Very high94.1Very high0 Ų016.4 Ų16.40%012%0.123CC..G310 helixtrans-84.7-7.4174.3-53.7-176.7000113.5L78 N80 W82 E164 Y167 A168 A171 Y174 E175 G179L78-L177 HydrophobicContact CD2-CB 3.95Å; N80-L177 HydrophobicContact CB-CB 4.24Å; N80-L177 WeakPolarHBondContact CB-O 3.36Å; W82-L177 HydrophobicContact CZ2-CD2 4.49Å; W82-L177 PolarHBondContact NE1-O 2.94Å; E164-L177 HydrophobicContact CG-CD1 4.23Å; Y167-L177 HydrophobicContact CD1-CD1 4.16Å; Y167-L177 HydrophobicContact CD1-CD2 3.58Å; Y167-L177 HydrophobicContact CE1-CD2 3.94Å; A168-L177 HydrophobicContact CB-CD1 3.83Å; A168-L177 HydrophobicContact CB-CG 4.36Å; A171-L177 HydrophobicContact CB-CD2 3.53Å; A171-L177 HydrophobicContact CB-CG 4.4Å; Y174-L177 WeakPolarHBondContact O-CB 3.28Å; Y174-L177 PolarHBondContact O-N 2.85Å; E175-L177 PolarHBondContact O-N 3.3Å; L177-G179 PolarHBondContact O-N 2.83Å
178D90.8Very high94Very high80 Ų8016.6 Ų16.643%0.42812%0.124SC..SBendtrans-67.3116.4174.9-162.39.5000110.2L78 G79 E175 K414L78-D178 HydrophobicContact CD1-CB 3.84Å; G79-D178 VanDerWaalsContact CA-OD1 3.23Å; G79-D178 WeakPolarHBondContact CA-OD1 3.48Å; G79-D178 PolarHBondContact N-OD1 3.05Å; E175-D178 VanDerWaalsContact O-CB 3.3Å; E175-D178 WeakPolarHBondContact O-CB 3.36Å; E175-D178 PolarHBondContact O-N 2.79Å; E175-D178 VanDerWaalsContact O-N 3.08Å; D178-K414 PolarHBondContact O-NZ 2.85Å
179G86.4Confident93.9Very high43 Ų4316.6 Ų16.644%0.44312%0.124SC..SBendtrans68.9123.1-171.400000114.2G79 L177 K414G79-G179 PolarHBondContact O-N 3.42Å; G79-G179 VanDerWaalsContact O-N 3.08Å; L177-G179 PolarHBondContact O-N 2.83Å; G179-K414 PolarHBondContact O-NZ 2.83Å; G179-K414 VanDerWaalsContact O-NZ 3.16Å
180G87.6Confident93.6Very high46 Ų4617.2 Ų17.247%0.47413%0.128SC..  trans-174.8-173.7178.700000112.9W82W82-G180 VanDerWaalsContact CD1-N 3.33Å; W82-G180 VanDerWaalsContact CE2-CA 3.5Å; W82-G180 VanDerWaalsContact CG-C 3.49Å
181S90.8Very high93.5Very high38 Ų3816.3 Ų16.327%0.26613%0.127SC..  trans-113127.7-176.2169.30000111.3W82 A183 D184 A185W82-S181 VanDerWaalsContact CE3-C 3.43Å; W82-S181 VanDerWaalsContact CZ3-O 3.3Å; W82-S181 WeakPolarHBondContact CZ3-O 3.46Å; S181-A183 VanDerWaalsContact C-N 3.29Å; S181-A183 PolarHBondContact O-N 3.29Å; S181-A183 PolarHBondContact OG-N 2.9Å; S181-D184 WeakPolarHBondContact O-CB 3.14Å; S181-D184 PolarHBondContact O-N 2.85Å; S181-A185 PolarHBondContact O-N 3.37Å
182A92.9Very high93.4Very high5 Ų516.3 Ų16.34%0.04113%0.127CC..Hα-helixtrans-61.8-39.1177.100000111.4W82 D184 A185 I186 S229 A253W82-A182 HydrophobicContact CB-CB 4.35Å; W82-A182 WeakPolarHBondContact O-CA 3.38Å; W82-A182 WeakPolarHBondContact O-CB 3.22Å; A182-D184 VanDerWaalsContact C-N 3.25Å; A182-D184 PolarHBondContact O-N 3.06Å; A182-A185 PolarHBondContact O-N 2.87Å; A182-I186 VanDerWaalsContact O-CG1 3.28Å; A182-I186 WeakPolarHBondContact O-CG1 3.36Å; A182-I186 PolarHBondContact O-N 3.39Å; A182-S229 WeakPolarHBondContact CB-OG 3.3Å; A182-A253 HydrophobicContact CB-CB 4.43Å
183A93.4Very high93.2Very high4 Ų414.5 Ų14.53%0.03311%0.108CC..Hα-helixtrans-53-43.1170.600000112.6S181 I186 V187 A194 D338S181-A183 VanDerWaalsContact C-N 3.29Å; S181-A183 PolarHBondContact O-N 3.29Å; S181-A183 PolarHBondContact OG-N 2.9Å; A183-I186 PolarHBondContact O-N 2.94Å; A183-V187 VanDerWaalsContact O-CG2 3.27Å; A183-V187 WeakPolarHBondContact O-CG2 3.44Å; A183-V187 PolarHBondContact O-N 2.95Å; A183-A194 HydrophobicContact CB-CB 3.75Å; A183-D338 HydrophobicContact CB-CB 3.88Å; A183-D338 PolarHBondContact N-OD2 3.45Å
184D94.2Very high93.1Very high21 Ų2114.6 Ų14.611%0.11211%0.108CC..Hα-helixtrans-65.7-45.7-179.9-83.2-33.5000112.4S181 A182 I186 V187 D188 R457S181-D184 WeakPolarHBondContact O-CB 3.14Å; S181-D184 PolarHBondContact O-N 2.85Å; A182-D184 VanDerWaalsContact C-N 3.25Å; A182-D184 PolarHBondContact O-N 3.06Å; D184-I186 PolarHBondContact O-N 2.83Å; D184-V187 PolarHBondContact O-N 2.82Å; D184-D188 PolarHBondContact O-N 3.48Å; D184-R457 VanDerWaalsContact C-NH2 3.31Å; D184-R457 PolarHBondContact O-NH2 3.34Å; D184-R457 WeakPolarHBondContact OD1-CB 3.36Å; D184-R457 IonicContact OD1-CZ 3.67Å; D184-R457 IonicContact OD1-NE 3.28Å; D184-R457 PolarHBondContact OD1-NE 3.44Å; D184-R457 IonicContact OD1-NH2 3.98Å; D184-R457 PolarHBondContact OD1-NH2 3.12Å; D184-R457 VanDerWaalsContact OD2-CB 3.26Å; D184-R457 WeakPolarHBondContact OD2-CB 3.17Å; D184-R457 IonicContact OD2-NE 2.72Å; D184-R457 PolarHBondContact OD2-NE 2.86Å
185A95.1Very high92.9Very high0 Ų015.8 Ų15.80%011%0.114CC..Hα-helixtrans-61.8-42.5173.700000111.9W82 A86 S181 A182 V187 D188 F189W82-A185 HydrophobicContact CE3-CB 3.78Å; W82-A185 HydrophobicContact CZ3-CB 3.45Å; W82-A185 VanDerWaalsContact CZ3-CB 3.45Å; A86-A185 HydrophobicContact CB-CB 3.35Å; S181-A185 PolarHBondContact O-N 3.37Å; A182-A185 PolarHBondContact O-N 2.87Å; A185-V187 VanDerWaalsContact C-N 3.3Å; A185-V187 PolarHBondContact O-N 2.89Å; A185-D188 CarbonylContact O-C 3.58Å; A185-D188 WeakPolarHBondContact O-CA 3.18Å; A185-D188 WeakPolarHBondContact O-CB 3.27Å; A185-D188 PolarHBondContact O-N 2.71Å; A185-F189 HydrophobicContact CB-CE2 3.98Å; A185-F189 HydrophobicContact CB-CZ 4.08Å; A185-F189 VanDerWaalsContact O-CD2 3.24Å; A185-F189 WeakPolarHBondContact O-CD2 3.45Å; A185-F189 WeakPolarHBondContact O-CG 3.21Å; A185-F189 PolarHBondContact O-N 2.83Å
186I95.1Very high92.7Very high0 Ų018.7 Ų18.70%014%0.136CC..Hα-helixtrans-60.2-42.9176.9-68.7166.8000110.8A86 C89 A182 A183 D184 D188 F189 T190 L227 C340A86-I186 HydrophobicContact CB-CG1 3.69Å; C89-I186 HydrophobicContact CB-CD1 4.39Å; A182-I186 VanDerWaalsContact O-CG1 3.28Å; A182-I186 WeakPolarHBondContact O-CG1 3.36Å; A182-I186 PolarHBondContact O-N 3.39Å; A183-I186 PolarHBondContact O-N 2.94Å; D184-I186 PolarHBondContact O-N 2.83Å; I186-D188 VanDerWaalsContact C-N 3.3Å; I186-D188 PolarHBondContact O-N 2.73Å; I186-F189 PolarHBondContact O-N 3.34Å; I186-T190 HydrophobicContact CG2-CG2 4.46Å; I186-T190 WeakPolarHBondContact O-CB 3.39Å; I186-T190 WeakPolarHBondContact O-CG2 3.36Å; I186-T190 PolarHBondContact O-N 2.57Å; I186-T190 VanDerWaalsContact O-N 3.12Å; I186-T190 PolarHBondContact O-OG1 3.47Å; I186-L227 HydrophobicContact CD1-CB 4.23Å; I186-L227 HydrophobicContact CG2-CB 3.91Å; I186-L227 HydrophobicContact CG2-CD1 3.83Å; I186-L227 HydrophobicContact CG2-CG 4.42Å; I186-C340 HydrophobicContact CB-CB 4.23Å; I186-C340 HydrophobicContact CD1-CB 4.49Å; I186-C340 HydrophobicContact CG2-CB 3.34Å; I186-C340 VanDerWaalsContact CG2-SG 3.53Å
187V95.1Very high92.6Very high0 Ų019.5 Ų19.50%014%0.141CC..Hα-helixtrans-60.6-42.6174.3169.70000110.5W126 A183 D184 A185 F189 T190 G191 A194W126-V187 HydrophobicContact CE3-CG1 3.57Å; W126-V187 HydrophobicContact CZ3-CG1 3.44Å; W126-V187 VanDerWaalsContact CZ3-CG1 3.44Å; A183-V187 VanDerWaalsContact O-CG2 3.27Å; A183-V187 WeakPolarHBondContact O-CG2 3.44Å; A183-V187 PolarHBondContact O-N 2.95Å; D184-V187 PolarHBondContact O-N 2.82Å; A185-V187 VanDerWaalsContact C-N 3.3Å; A185-V187 PolarHBondContact O-N 2.89Å; V187-F189 VanDerWaalsContact C-N 3.26Å; V187-F189 PolarHBondContact O-N 2.79Å; V187-T190 PolarHBondContact O-N 2.87Å; V187-G191 WeakPolarHBondContact O-CA 3.18Å; V187-G191 PolarHBondContact O-N 3.44Å; V187-A194 HydrophobicContact CG2-CB 3.9Å
188D95.9Very high92.6Very high4 Ų422.5 Ų22.52%0.02116%0.157CC..Hα-helixtrans-66.4-26177.4-62.2-9.2000112.4F125 W126 Y167 D184 A185 I186 R411 R457F125-D188 CarbonylContact C-O 3.59Å; F125-D188 WeakPolarHBondContact CA-O 3.43Å; W126-D188 PolarHBondContact N-O 3.46Å; W126-D188 WeakPolarHBondContact O-CA 2.99Å; Y167-D188 HydrophobicContact CE2-CB 4.01Å; Y167-D188 PolarHBondContact OH-OD2 2.94Å; D184-D188 PolarHBondContact O-N 3.48Å; A185-D188 CarbonylContact O-C 3.58Å; A185-D188 WeakPolarHBondContact O-CA 3.18Å; A185-D188 WeakPolarHBondContact O-CB 3.27Å; A185-D188 PolarHBondContact O-N 2.71Å; I186-D188 VanDerWaalsContact C-N 3.3Å; I186-D188 PolarHBondContact O-N 2.73Å; D188-R411 IonicContact OD2-NH2 3Å; D188-R411 PolarHBondContact OD2-NH2 3.49Å; D188-R457 IonicContact OD1-CZ 2.78Å; D188-R457 VanDerWaalsContact OD1-CZ 3.3Å; D188-R457 IonicContact OD1-NH1 3.88Å; D188-R457 PolarHBondContact OD1-NH1 3.18Å; D188-R457 IonicContact OD1-NH2 2.72Å; D188-R457 PolarHBondContact OD1-NH2 3.36Å; D188-R457 IonicContact OD2-CZ 2.79Å; D188-R457 IonicContact OD2-NH1 3.88Å; D188-R457 PolarHBondContact OD2-NH1 3.49Å; D188-R457 IonicContact OD2-NH2 2.72Å
189F94.5Very high92.8Very high1 Ų118.8 Ų18.80%0.00414%0.137CC..Hα-helixtrans-85.5-17.2176.1-59-29.3000114.1F83 A86 C87 L90 V100 F125 W131 Y167 A185 I186 V187F83-F189 AromaticContact CD2-CZ 3.84Å; F83-F189 HydrophobicContact CD2-CZ 3.84Å; F83-F189 HydrophobicContact CE2-CE1 4.05Å; F83-F189 AromaticContact CE2-CZ 3.52Å; F83-F189 HydrophobicContact CE2-CZ 3.52Å; F83-F189 HydrophobicContact CZ-CZ 4.33Å; A86-F189 HydrophobicContact CB-CD2 4.2Å; A86-F189 HydrophobicContact CB-CE2 3.63Å; C87-F189 VanDerWaalsContact SG-CZ 3.56Å; L90-F189 HydrophobicContact CB-CD2 4.26Å; L90-F189 HydrophobicContact CD1-CB 4.06Å; L90-F189 HydrophobicContact CD2-CB 4.05Å; L90-F189 HydrophobicContact CD2-CD2 4.04Å; L90-F189 HydrophobicContact CD2-CG 3.95Å; V100-F189 HydrophobicContact CG1-CD1 4.5Å; V100-F189 HydrophobicContact CG2-CB 3.97Å; V100-F189 HydrophobicContact CG2-CD1 4.5Å; V100-F189 WeakPolarHBondContact CG2-O 3.46Å; F125-F189 AromaticContact CD1-CD1 3.93Å; F125-F189 HydrophobicContact CD1-CD1 3.93Å; F125-F189 AromaticContact CD1-CE1 3.94Å; F125-F189 HydrophobicContact CD1-CE1 3.94Å; F125-F189 HydrophobicContact CE1-CD1 4.1Å; F125-F189 AromaticContact CE1-CE1 3.76Å; F125-F189 HydrophobicContact CE1-CE1 3.76Å; W131-F189 WeakPolarHBondContact CH2-O 3.42Å; Y167-F189 HydrophobicContact CE2-CE1 4.5Å; A185-F189 HydrophobicContact CB-CE2 3.98Å; A185-F189 HydrophobicContact CB-CZ 4.08Å; A185-F189 VanDerWaalsContact O-CD2 3.24Å; A185-F189 WeakPolarHBondContact O-CD2 3.45Å; A185-F189 WeakPolarHBondContact O-CG 3.21Å; A185-F189 PolarHBondContact O-N 2.83Å; I186-F189 PolarHBondContact O-N 3.34Å; V187-F189 VanDerWaalsContact C-N 3.26Å; V187-F189 PolarHBondContact O-N 2.79Å
190T92.8Very high93Very high16 Ų1622.3 Ų22.310%0.09815%0.145CC..Hα-helixtrans-137.4-21-163.165.60000115L90 L96 I186 V187 A192 L227 I342L90-T190 HydrophobicContact CD1-CG2 4.42Å; L96-T190 HydrophobicContact CB-CG2 4.41Å; L96-T190 HydrophobicContact CD1-CG2 3.82Å; L96-T190 HydrophobicContact CD2-CG2 4.46Å; L96-T190 HydrophobicContact CG-CG2 4.46Å; I186-T190 HydrophobicContact CG2-CG2 4.46Å; I186-T190 WeakPolarHBondContact O-CB 3.39Å; I186-T190 WeakPolarHBondContact O-CG2 3.36Å; I186-T190 PolarHBondContact O-N 2.57Å; I186-T190 VanDerWaalsContact O-N 3.12Å; I186-T190 PolarHBondContact O-OG1 3.47Å; V187-T190 PolarHBondContact O-N 2.87Å; T190-A192 PolarHBondContact O-N 2.85Å; T190-A192 WeakPolarHBondContact OG1-CB 3.22Å; T190-A192 PolarHBondContact OG1-N 2.81Å; T190-L227 HydrophobicContact CG2-CD1 3.99Å; T190-I342 HydrophobicContact CG2-CD1 4.24Å
191G92.1Very high93.2Very high15 Ų1526.5 Ų26.516%0.15515%0.152CC..  trans66.119.2-165.200000114W126 V187 R488W126-G191 VanDerWaalsContact CD2-CA 3.48Å; V187-G191 WeakPolarHBondContact O-CA 3.18Å; V187-G191 PolarHBondContact O-N 3.44Å; G191-R488 PolarHBondContact O-NH1 3.14Å
192A92.8Very high93.2Very high3 Ų325.9 Ų25.93%0.02515%0.152CC..  trans-59.6171.4177.500000112.8T190 C340 I342 R488T190-A192 PolarHBondContact O-N 2.85Å; T190-A192 WeakPolarHBondContact OG1-CB 3.22Å; T190-A192 PolarHBondContact OG1-N 2.81Å; A192-C340 HydrophobicContact CB-CB 4.09Å; A192-I342 HydrophobicContact CB-CD1 3.99Å; A192-R488 PolarHBondContact O-NH1 3.24Å
193V92.2Very high93.3Very high3 Ų331 Ų312%0.01817%0.173CC..EExtended strand (participates in β ladder)trans-108.2115.5168.1-175.50000108.5R341 V343 F460 F490V193-R341 PolarHBondContact N-O 3.39Å; V193-R341 VanDerWaalsContact N-O 3.11Å; V193-R341 PolarHBondContact O-N 3.05Å; V193-V343 HydrophobicContact CB-CG2 4.37Å; V193-V343 HydrophobicContact CG2-CG2 3.91Å; V193-F460 HydrophobicContact CG1-CD2 3.42Å; V193-F460 VanDerWaalsContact CG1-CD2 3.42Å; V193-F460 HydrophobicContact CG1-CE2 3.43Å; V193-F460 VanDerWaalsContact CG1-CE2 3.43Å; V193-F490 HydrophobicContact CG2-CD2 4.41Å; V193-F490 HydrophobicContact CG2-CE1 4.27Å; V193-F490 HydrophobicContact CG2-CE2 3.42Å; V193-F490 VanDerWaalsContact CG2-CE2 3.42Å; V193-F490 HydrophobicContact CG2-CZ 3.32Å
194A93.4Very high93.3Very high6 Ų632.4 Ų32.45%0.0518%0.178CC..EExtended strand (participates in β ladder)trans-86.4137.7176.900000111.6A183 V187 F460A183-A194 HydrophobicContact CB-CB 3.75Å; V187-A194 HydrophobicContact CG2-CB 3.9Å; A194-F460 VanDerWaalsContact O-CB 3.28Å; A194-F460 WeakPolarHBondContact O-CB 3.48Å
195E92.4Very high93.2Very high26 Ų2639.4 Ų39.412%0.12120%0.203CC..EExtended strand (participates in β ladder)trans-125120.3166.6174.1179.1-163.100107.3V197 I339 R341 F460 K462E195-V197 HydrophobicContact CG-CG2 4.04Å; E195-I339 HydrophobicContact CB-CB 4.49Å; E195-I339 PolarHBondContact N-O 3.27Å; E195-I339 PolarHBondContact O-N 2.73Å; E195-R341 VanDerWaalsContact CB-NH1 3.35Å; E195-R341 IonicContact OE2-CZ 2.66Å; E195-R341 IonicContact OE2-NH1 2.6Å; E195-R341 PolarHBondContact OE2-NH1 3.28Å; E195-R341 IonicContact OE2-NH2 2.82Å; E195-R341 PolarHBondContact OE2-NH2 3.09Å; E195-F460 HydrophobicContact CB-CD1 3.51Å; E195-F460 HydrophobicContact CB-CE1 3.73Å; E195-F460 HydrophobicContact CB-CG 4.12Å; E195-F460 HydrophobicContact CG-CD1 3.55Å; E195-F460 HydrophobicContact CG-CE1 3.75Å; E195-K462 IonicContact OE1-NZ 3.42Å; E195-K462 PolarHBondContact OE1-NZ 2.74Å; E195-K462 IonicContact OE2-NZ 3.98Å; E195-K462 PolarHBondContact OE2-NZ 3.17Å
196S91.5Very high93.1Very high80 Ų8046.1 Ų46.156%0.55923%0.234SC*.EExtended strand (participates in β ladder)trans-92.2133.4171.2-52.70000109.2V337 D338S196-V337 CarbonylContact C-O 3.55Å; S196-V337 WeakPolarHBondContact CA-O 3.27Å; S196-D338 VanDerWaalsContact CB-OD1 3.3Å; S196-D338 WeakPolarHBondContact CB-OD1 3.49Å; S196-D338 PolarHBondContact OG-OD1 2.85Å
197V92.3Very high93Very high19 Ų1949.3 Ų49.312%0.11525%0.25CS..EExtended strand (participates in β ladder)trans-121.9122.4179.21800000108.8E195 Y204 V337 I339E195-V197 HydrophobicContact CG-CG2 4.04Å; V197-Y204 HydrophobicContact CG1-CE2 3.74Å; V197-V337 HydrophobicContact CB-CG1 3.74Å; V197-V337 HydrophobicContact CG1-CG1 4.42Å; V197-V337 HydrophobicContact CG2-CG1 4.45Å; V197-V337 PolarHBondContact N-O 3.14Å; V197-V337 PolarHBondContact O-N 3.47Å; V197-I339 HydrophobicContact CG2-CD1 3.8Å
198D92.9Very high92.8Very high62 Ų6255 Ų5533%0.33228%0.279SS..EExtended strand (participates in β ladder)trans-80.9115.1172.1-178-31.1000109.4I200 Q201 G202D198-I200 VanDerWaalsContact C-N 3.33Å; D198-I200 WeakPolarHBondContact OD1-CA 3.37Å; D198-I200 WeakPolarHBondContact OD1-CB 3.43Å; D198-I200 PolarHBondContact OD1-N 3.4Å; D198-Q201 HydrophobicContact CB-CB 3.97Å; D198-Q201 PolarHBondContact OD1-N 3.17Å; D198-G202 PolarHBondContact O-N 2.99Å
199L94.7Very high92.7Very high2 Ų257.9 Ų57.91%0.0130%0.3CS..THydrogen-bonded Turntrans-73.5-26.8-176.9-60.4176.9000112.5K203 Y204 L214 W330 F334 T335 V337L199-K203 PolarHBondContact O-N 2.62Å; L199-Y204 HydrophobicContact CB-CD2 4.38Å; L199-Y204 HydrophobicContact CD2-CD2 3.92Å; L199-Y204 HydrophobicContact CD2-CE2 4.33Å; L199-Y204 HydrophobicContact CD2-CG 4.26Å; L199-Y204 WeakPolarHBondContact O-CD2 3.19Å; L199-Y204 PolarHBondContact O-N 2.95Å; L199-L214 HydrophobicContact CD2-CD2 3.52Å; L199-W330 HydrophobicContact CD1-CE3 4.33Å; L199-W330 HydrophobicContact CD1-CH2 3.52Å; L199-W330 HydrophobicContact CD1-CZ2 3.91Å; L199-W330 HydrophobicContact CD1-CZ3 3.74Å; L199-W330 HydrophobicContact CD2-CH2 3.87Å; L199-W330 HydrophobicContact CD2-CZ3 3.88Å; L199-W330 HydrophobicContact CG-CH2 4.3Å; L199-W330 HydrophobicContact CG-CZ3 4.5Å; L199-F334 HydrophobicContact CD1-CB 3.83Å; L199-T335 VanDerWaalsContact CB-O 3.31Å; L199-T335 WeakPolarHBondContact CB-O 3.31Å; L199-T335 PolarHBondContact N-O 3.19Å; L199-V337 HydrophobicContact CD2-CG1 3.99Å
200I92.3Very high92.6Very high118 Ų11860.7 Ų60.761%0.60531%0.313SS*.THydrogen-bonded Turntrans-77.8-54.3179.1-58.5172.6000109.2D198 G202 K203 T335D198-I200 VanDerWaalsContact C-N 3.33Å; D198-I200 WeakPolarHBondContact OD1-CA 3.37Å; D198-I200 WeakPolarHBondContact OD1-CB 3.43Å; D198-I200 PolarHBondContact OD1-N 3.4Å; I200-G202 VanDerWaalsContact C-N 3.26Å; I200-G202 PolarHBondContact O-N 3.29Å; I200-K203 WeakPolarHBondContact O-CA 3.21Å; I200-K203 PolarHBondContact O-N 3.06Å; I200-T335 HydrophobicContact CD1-CG2 3.79Å; I200-T335 HydrophobicContact CG1-CG2 4.46Å
201Q91.3Very high92.6Very high133 Ų13361 Ų6162%0.62131%0.314SS*.THydrogen-bonded Turntrans-62-36.3179.4-169.3-178.521.400111.5D198 K203D198-Q201 HydrophobicContact CB-CB 3.97Å; D198-Q201 PolarHBondContact OD1-N 3.17Å; Q201-K203 PolarHBondContact O-N 2.72Å
202G91.1Very high92.7Very high26 Ų2663.6 Ų63.627%0.26832%0.323SS..THydrogen-bonded Turntrans-75.6-3.8174.700000114.9D198 I200 Y204D198-G202 PolarHBondContact O-N 2.99Å; I200-G202 VanDerWaalsContact C-N 3.26Å; I200-G202 PolarHBondContact O-N 3.29Å; G202-Y204 PolarHBondContact O-N 2.91Å
203K93.8Very high92.7Very high111 Ų11169.2 Ų69.248%0.48335%0.347SS..THydrogen-bonded Turntrans54.334.2178.7-56.5-174.3177.2-1680113.9L199 I200 Q201 R205 E206 I207L199-K203 PolarHBondContact O-N 2.62Å; I200-K203 WeakPolarHBondContact O-CA 3.21Å; I200-K203 PolarHBondContact O-N 3.06Å; Q201-K203 PolarHBondContact O-N 2.72Å; K203-R205 PolarHBondContact O-N 3.1Å; K203-E206 PolarHBondContact O-N 3.15Å; K203-I207 HydrophobicContact CB-CD1 3.81Å; K203-I207 HydrophobicContact CB-CG1 4.02Å; K203-I207 HydrophobicContact CD-CD1 4.14Å; K203-I207 PolarHBondContact O-N 2.85Å
204Y93.3Very high92.8Very high35 Ų3569.5 Ų69.514%0.13735%0.348CS..THydrogen-bonded Turntrans-68.6-17.7-177.4-65.6-83.8000113.3V197 L199 G202 E210 Q211 L214V197-Y204 HydrophobicContact CG1-CE2 3.74Å; L199-Y204 HydrophobicContact CB-CD2 4.38Å; L199-Y204 HydrophobicContact CD2-CD2 3.92Å; L199-Y204 HydrophobicContact CD2-CE2 4.33Å; L199-Y204 HydrophobicContact CD2-CG 4.26Å; L199-Y204 WeakPolarHBondContact O-CD2 3.19Å; L199-Y204 PolarHBondContact O-N 2.95Å; G202-Y204 PolarHBondContact O-N 2.91Å; Y204-E210 HydrophobicContact CD1-CB 3.93Å; Y204-E210 HydrophobicContact CE1-CB 3.89Å; Y204-E210 WeakPolarHBondContact CE1-O 3.45Å; Y204-Q211 PolarHBondContact O-NE2 3.12Å; Y204-Q211 VanDerWaalsContact O-NE2 3.16Å; Y204-L214 HydrophobicContact CD1-CB 3.89Å; Y204-L214 HydrophobicContact CD1-CD2 3.69Å; Y204-L214 HydrophobicContact CD1-CG 4.4Å; Y204-L214 HydrophobicContact CD2-CD2 4.43Å; Y204-L214 HydrophobicContact CE1-CB 3.66Å; Y204-L214 HydrophobicContact CE1-CD2 3.83Å; Y204-L214 HydrophobicContact CE1-CG 4.21Å; Y204-L214 HydrophobicContact CE2-CD2 4.47Å; Y204-L214 HydrophobicContact CG-CD2 4.01Å
205R92.2Very high93Very high168 Ų16869.2 Ų69.263%0.63435%0.346SS*.THydrogen-bonded Turntrans-70.9-32.9170.1-178.9172.9176.9172.1-1113.1K203 K332K203-R205 PolarHBondContact O-N 3.1Å; R205-K332 HydrophobicContact CG-CG 3.99Å
206E92.6Very high93.1Very high141 Ų14171.6 Ų71.666%0.65936%0.357SS*.THydrogen-bonded Turntrans-102.3-36.5-170.2-62.6168.9-172.100111.9K203K203-E206 PolarHBondContact O-N 3.15Å
207I93.8Very high93.2Very high67 Ų6770 Ų7034%0.34434%0.342SS..  trans-103.998.7-170.3-52.5179.6000110.3K203 S209 E210 Q211K203-I207 HydrophobicContact CB-CD1 3.81Å; K203-I207 HydrophobicContact CB-CG1 4.02Å; K203-I207 HydrophobicContact CD-CD1 4.14Å; K203-I207 PolarHBondContact O-N 2.85Å; I207-S209 VanDerWaalsContact C-N 3.26Å; I207-S209 WeakPolarHBondContact CG2-OG 3.43Å; I207-S209 PolarHBondContact O-N 3.04Å; I207-E210 HydrophobicContact CB-CB 4.33Å; I207-E210 HydrophobicContact CB-CG 4.32Å; I207-E210 HydrophobicContact CG2-CB 4.2Å; I207-E210 HydrophobicContact CG2-CG 3.85Å; I207-E210 PolarHBondContact O-N 2.69Å; I207-E210 VanDerWaalsContact O-N 3.13Å; I207-Q211 PolarHBondContact O-N 3.22Å
208I91.1Very high93.3Very high118 Ų11869.1 Ų69.161%0.60534%0.337SS*.Hα-helixtrans-55.7-38.6-178.6-61172.1000112.1E210 Q211 I212I208-E210 PolarHBondContact O-N 3.18Å; I208-Q211 WeakPolarHBondContact O-CB 3.19Å; I208-Q211 PolarHBondContact O-N 3.27Å; I208-I212 HydrophobicContact CG2-CD1 3.83Å; I208-I212 HydrophobicContact CG2-CG1 4.29Å; I208-I212 VanDerWaalsContact O-CG1 3.26Å; I208-I212 WeakPolarHBondContact O-CG1 3.35Å; I208-I212 PolarHBondContact O-N 3.27Å
209S93.1Very high93.4Very high65 Ų6567.5 Ų67.546%0.45533%0.328SS..Hα-helixtrans-66.1-36.9-179.157.60000113I207 K213I207-S209 VanDerWaalsContact C-N 3.26Å; I207-S209 WeakPolarHBondContact CG2-OG 3.43Å; I207-S209 PolarHBondContact O-N 3.04Å; S209-K213 VanDerWaalsContact O-CG 3.3Å; S209-K213 WeakPolarHBondContact O-CG 3.07Å; S209-K213 PolarHBondContact O-N 3.42Å; S209-K213 VanDerWaalsContact O-N 3.14Å
210E92.8Very high93.3Very high61 Ų6172 Ų7229%0.28535%0.347SS..Hα-helixtrans-73.7-37.9174.8-65.4-52.4132.400111.3Y204 I207 I208 I212 K213 L214Y204-E210 HydrophobicContact CD1-CB 3.93Å; Y204-E210 HydrophobicContact CE1-CB 3.89Å; Y204-E210 WeakPolarHBondContact CE1-O 3.45Å; I207-E210 HydrophobicContact CB-CB 4.33Å; I207-E210 HydrophobicContact CB-CG 4.32Å; I207-E210 HydrophobicContact CG2-CB 4.2Å; I207-E210 HydrophobicContact CG2-CG 3.85Å; I207-E210 PolarHBondContact O-N 2.69Å; I207-E210 VanDerWaalsContact O-N 3.13Å; I208-E210 PolarHBondContact O-N 3.18Å; E210-I212 VanDerWaalsContact C-N 3.35Å; E210-I212 PolarHBondContact O-N 2.8Å; E210-K213 PolarHBondContact O-N 3.38Å; E210-K213 IonicContact OE1-NZ 3.32Å; E210-K213 PolarHBondContact OE1-NZ 3.42Å; E210-K213 IonicContact OE2-NZ 2.78Å; E210-L214 WeakPolarHBondContact O-CB 3.36Å; E210-L214 PolarHBondContact O-N 3.02Å
211Q93.9Very high93.3Very high22 Ų2266.8 Ų66.810%0.10332%0.321CS..Hα-helixtrans-56.3-47.9171.9-175-179.491.900111.6Y204 I207 I208 K213 L214 F215 F327Y204-Q211 PolarHBondContact O-NE2 3.12Å; Y204-Q211 VanDerWaalsContact O-NE2 3.16Å; I207-Q211 PolarHBondContact O-N 3.22Å; I208-Q211 WeakPolarHBondContact O-CB 3.19Å; I208-Q211 PolarHBondContact O-N 3.27Å; Q211-K213 PolarHBondContact O-N 3.08Å; Q211-L214 PolarHBondContact O-N 3.1Å; Q211-F215 PolarHBondContact O-N 2.87Å; Q211-F327 HydrophobicContact CG-CD1 3.67Å; Q211-F327 HydrophobicContact CG-CE1 3.71Å; Q211-F327 VanDerWaalsContact O-CE1 3.29Å; Q211-F327 WeakPolarHBondContact O-CE1 3.1Å
212I92.4Very high93.3Very high70 Ų7062 Ų6236%0.35930%0.299SS..Hα-helixtrans-63-43.4177.6-66.6172000111.1I208 E210 L214 F215 E216 F278I208-I212 HydrophobicContact CG2-CD1 3.83Å; I208-I212 HydrophobicContact CG2-CG1 4.29Å; I208-I212 VanDerWaalsContact O-CG1 3.26Å; I208-I212 WeakPolarHBondContact O-CG1 3.35Å; I208-I212 PolarHBondContact O-N 3.27Å; E210-I212 VanDerWaalsContact C-N 3.35Å; E210-I212 PolarHBondContact O-N 2.8Å; I212-L214 VanDerWaalsContact C-N 3.35Å; I212-L214 PolarHBondContact O-N 2.97Å; I212-F215 PolarHBondContact O-N 2.81Å; I212-E216 WeakPolarHBondContact O-CG 3.43Å; I212-E216 PolarHBondContact O-N 2.86Å; I212-E216 VanDerWaalsContact O-N 3.07Å; I212-F278 HydrophobicContact CG1-CE2 4.15Å
213K93.9Very high93.3Very high121 Ų12165.2 Ų65.253%0.52631%0.313SS..Hα-helixtrans-61.7-42.7177.5-73.7170.7-170.6170.50111.9S209 E210 Q211 E216 D217S209-K213 VanDerWaalsContact O-CG 3.3Å; S209-K213 WeakPolarHBondContact O-CG 3.07Å; S209-K213 PolarHBondContact O-N 3.42Å; S209-K213 VanDerWaalsContact O-N 3.14Å; E210-K213 PolarHBondContact O-N 3.38Å; E210-K213 IonicContact OE1-NZ 3.32Å; E210-K213 PolarHBondContact OE1-NZ 3.42Å; E210-K213 IonicContact OE2-NZ 2.78Å; Q211-K213 PolarHBondContact O-N 3.08Å; K213-E216 PolarHBondContact O-N 3.19Å; K213-D217 PolarHBondContact O-N 2.83Å
214L95.1Very high93Very high9 Ų965.8 Ų65.85%0.04731%0.313CS..Hα-helixtrans-63.1-46.8177.3-178.962.9000110.7L199 Y204 E210 Q211 I212 E216 D217 L218 F327 W330 I339L199-L214 HydrophobicContact CD2-CD2 3.52Å; Y204-L214 HydrophobicContact CD1-CB 3.89Å; Y204-L214 HydrophobicContact CD1-CD2 3.69Å; Y204-L214 HydrophobicContact CD1-CG 4.4Å; Y204-L214 HydrophobicContact CD2-CD2 4.43Å; Y204-L214 HydrophobicContact CE1-CB 3.66Å; Y204-L214 HydrophobicContact CE1-CD2 3.83Å; Y204-L214 HydrophobicContact CE1-CG 4.21Å; Y204-L214 HydrophobicContact CE2-CD2 4.47Å; Y204-L214 HydrophobicContact CG-CD2 4.01Å; E210-L214 WeakPolarHBondContact O-CB 3.36Å; E210-L214 PolarHBondContact O-N 3.02Å; Q211-L214 PolarHBondContact O-N 3.1Å; I212-L214 VanDerWaalsContact C-N 3.35Å; I212-L214 PolarHBondContact O-N 2.97Å; L214-E216 VanDerWaalsContact C-N 3.31Å; L214-E216 PolarHBondContact O-N 2.97Å; L214-D217 PolarHBondContact O-N 3.04Å; L214-D217 VanDerWaalsContact O-N 3.11Å; L214-L218 HydrophobicContact CD1-CD1 4.2Å; L214-L218 HydrophobicContact CD1-CD2 4.32Å; L214-L218 HydrophobicContact CD1-CG 4.01Å; L214-L218 HydrophobicContact CG-CD1 3.97Å; L214-L218 HydrophobicContact CG-CG 4.19Å; L214-L218 WeakPolarHBondContact O-CG 3.46Å; L214-L218 PolarHBondContact O-N 2.95Å; L214-F327 HydrophobicContact CB-CZ 4.32Å; L214-F327 HydrophobicContact CD2-CZ 4Å; L214-F327 HydrophobicContact CG-CZ 3.97Å; L214-W330 HydrophobicContact CD2-CH2 4.47Å; L214-W330 HydrophobicContact CD2-CZ3 3.97Å; L214-I339 HydrophobicContact CD1-CD1 4.47Å
215F96.2Very high92.8Very high0 Ų064.7 Ų64.70%031%0.312CS..Hα-helixtrans-54.7-47.1176.3179.6-96.8000112.2Q211 I212 D217 L218 L219 I259 K261 F278 F327Q211-F215 PolarHBondContact O-N 2.87Å; I212-F215 PolarHBondContact O-N 2.81Å; F215-D217 PolarHBondContact O-N 2.91Å; F215-L218 PolarHBondContact O-N 3.27Å; F215-L219 HydrophobicContact CE1-CD2 4.12Å; F215-L219 VanDerWaalsContact O-CB 3.23Å; F215-L219 WeakPolarHBondContact O-CB 3.28Å; F215-L219 PolarHBondContact O-N 3.32Å; F215-I259 HydrophobicContact CD2-CG2 4.04Å; F215-I259 HydrophobicContact CE2-CG2 3.42Å; F215-I259 VanDerWaalsContact CE2-CG2 3.42Å; F215-I259 HydrophobicContact CZ-CG2 3.79Å; F215-K261 HydrophobicContact CE1-CD 4.29Å; F215-K261 HydrophobicContact CE1-CG 3.66Å; F215-K261 HydrophobicContact CZ-CG 3.96Å; F215-F278 HydrophobicContact CD1-CB 4.36Å; F215-F278 HydrophobicContact CD1-CD1 4.16Å; F215-F278 HydrophobicContact CD1-CD2 4.19Å; F215-F278 AromaticContact CD1-CG 3.97Å; F215-F278 HydrophobicContact CD1-CG 3.97Å; F215-F278 HydrophobicContact CD2-CB 3.87Å; F215-F278 HydrophobicContact CD2-CG 4.35Å; F215-F278 HydrophobicContact CE1-CB 4.16Å; F215-F278 AromaticContact CE1-CD1 3.7Å; F215-F278 HydrophobicContact CE1-CD1 3.7Å; F215-F278 HydrophobicContact CE1-CE1 4.24Å; F215-F278 AromaticContact CE1-CG 3.86Å; F215-F278 HydrophobicContact CE1-CG 3.86Å; F215-F278 HydrophobicContact CE2-CB 3.63Å; F215-F278 HydrophobicContact CE2-CG 4.24Å; F215-F278 HydrophobicContact CG-CB 4.21Å; F215-F278 HydrophobicContact CG-CD2 4.32Å; F215-F278 HydrophobicContact CG-CG 4.21Å; F215-F278 HydrophobicContact CZ-CB 3.79Å; F215-F278 AromaticContact CZ-CD1 3.97Å; F215-F278 HydrophobicContact CZ-CD1 3.97Å; F215-F278 AromaticContact CZ-CG 4Å; F215-F278 HydrophobicContact CZ-CG 4Å; F215-F327 HydrophobicContact CB-CD1 3.81Å; F215-F327 HydrophobicContact CB-CE1 3.68Å; F215-F327 HydrophobicContact CB-CE2 4.43Å; F215-F327 HydrophobicContact CB-CG 4.25Å; F215-F327 HydrophobicContact CB-CZ 4Å; F215-F327 HydrophobicContact CD2-CB 3.95Å; F215-F327 HydrophobicContact CD2-CD1 4.02Å; F215-F327 AromaticContact CD2-CD2 3.62Å; F215-F327 HydrophobicContact CD2-CD2 3.62Å; F215-F327 HydrophobicContact CD2-CE1 4.46Å; F215-F327 HydrophobicContact CD2-CE2 4.09Å; F215-F327 AromaticContact CD2-CG 3.56Å; F215-F327 HydrophobicContact CD2-CG 3.56Å; F215-F327 HydrophobicContact CD2-CZ 4.48Å; F215-F327 HydrophobicContact CE2-CB 4.4Å; F215-F327 HydrophobicContact CE2-CD2 4.38Å; F215-F327 HydrophobicContact CE2-CG 4.4Å; F215-F327 HydrophobicContact CG-CD1 4.34Å; F215-F327 HydrophobicContact CG-CG 4.32Å
216E94.8Very high92.8Very high76 Ų7656.9 Ų56.936%0.35528%0.284SS..Hα-helixtrans-65.9-36.1178.5-63.6-69.8178.300112.4I212 K213 L214 K220 K261I212-E216 WeakPolarHBondContact O-CG 3.43Å; I212-E216 PolarHBondContact O-N 2.86Å; I212-E216 VanDerWaalsContact O-N 3.07Å; K213-E216 PolarHBondContact O-N 3.19Å; L214-E216 VanDerWaalsContact C-N 3.31Å; L214-E216 PolarHBondContact O-N 2.97Å; E216-K220 WeakPolarHBondContact O-CB 3.35Å; E216-K220 PolarHBondContact O-N 3Å; E216-K261 VanDerWaalsContact OE1-CE 3.27Å; E216-K261 WeakPolarHBondContact OE1-CE 3.38Å; E216-K261 IonicContact OE1-NZ 3.36Å; E216-K261 PolarHBondContact OE1-NZ 2.63Å; E216-K261 IonicContact OE2-NZ 3.05Å; E216-K261 PolarHBondContact OE2-NZ 2.9Å
217D93.1Very high92.9Very high45 Ų4550.4 Ų50.424%0.24125%0.254CS..Hα-helixtrans-67.8-46.5175.3-162.244.2000111.3K213 L214 F215 K220 V221 R341K213-D217 PolarHBondContact O-N 2.83Å; L214-D217 PolarHBondContact O-N 3.04Å; L214-D217 VanDerWaalsContact O-N 3.11Å; F215-D217 PolarHBondContact O-N 2.91Å; D217-K220 WeakPolarHBondContact O-CB 3.47Å; D217-K220 PolarHBondContact O-N 3.17Å; D217-V221 WeakPolarHBondContact O-CG2 3.38Å; D217-V221 PolarHBondContact O-N 2.94Å; D217-R341 IonicContact OD2-NH2 3.88Å; D217-R341 PolarHBondContact OD2-NH2 2.75Å
218L95.8Very high93Very high1 Ų147.3 Ų47.31%0.00524%0.238CC..Hα-helixtrans-63-45.2178-63.8179.4000111.3L214 F215 K220 V221 H222 I228 I259 F327 W330 V337 I339L214-L218 HydrophobicContact CD1-CD1 4.2Å; L214-L218 HydrophobicContact CD1-CD2 4.32Å; L214-L218 HydrophobicContact CD1-CG 4.01Å; L214-L218 HydrophobicContact CG-CD1 3.97Å; L214-L218 HydrophobicContact CG-CG 4.19Å; L214-L218 WeakPolarHBondContact O-CG 3.46Å; L214-L218 PolarHBondContact O-N 2.95Å; F215-L218 PolarHBondContact O-N 3.27Å; L218-K220 VanDerWaalsContact C-N 3.29Å; L218-K220 PolarHBondContact O-N 2.68Å; L218-V221 PolarHBondContact O-N 3.11Å; L218-H222 WeakPolarHBondContact O-CB 3.41Å; L218-H222 PolarHBondContact O-N 2.81Å; L218-I228 HydrophobicContact CB-CD1 4.13Å; L218-I228 HydrophobicContact CD2-CD1 4.03Å; L218-I228 HydrophobicContact CD2-CG2 4.26Å; L218-I259 HydrophobicContact CB-CD1 3.53Å; L218-F327 HydrophobicContact CD1-CE2 3.75Å; L218-F327 HydrophobicContact CD1-CZ 3.94Å; L218-W330 HydrophobicContact CD1-CH2 4.16Å; L218-W330 HydrophobicContact CD1-CZ3 4.3Å; L218-V337 HydrophobicContact CD2-CG2 4.25Å; L218-I339 HydrophobicContact CD2-CD1 3.48Å; L218-I339 VanDerWaalsContact CD2-CD1 3.48Å; L218-I339 HydrophobicContact CD2-CG1 3.58Å; L218-I339 HydrophobicContact CD2-CG2 4.33Å
219L95.1Very high93.2Very high28 Ų2841.7 Ų41.715%0.14721%0.209CC..Hα-helixtrans-57.6-43.8174.5177.361.3000111.2F215 T223 I259 K261F215-L219 HydrophobicContact CE1-CD2 4.12Å; F215-L219 VanDerWaalsContact O-CB 3.23Å; F215-L219 WeakPolarHBondContact O-CB 3.28Å; F215-L219 PolarHBondContact O-N 3.32Å; L219-T223 HydrophobicContact CD1-CG2 3.95Å; L219-T223 HydrophobicContact CG-CG2 4.44Å; L219-T223 WeakPolarHBondContact O-CB 3.21Å; L219-T223 VanDerWaalsContact O-CG2 3.22Å; L219-T223 WeakPolarHBondContact O-CG2 3.4Å; L219-T223 PolarHBondContact O-N 3.48Å; L219-T223 PolarHBondContact O-OG1 3.05Å; L219-I259 HydrophobicContact CB-CG2 3.93Å; L219-I259 HydrophobicContact CD1-CB 4.18Å; L219-I259 HydrophobicContact CD1-CG2 4.04Å; L219-I259 VanDerWaalsContact CD1-O 3.3Å; L219-I259 WeakPolarHBondContact CD1-O 3.36Å; L219-K261 HydrophobicContact CD2-CD 4.44Å; L219-K261 HydrophobicContact CD2-CG 4.47Å
220K92.1Very high93.3Very high96 Ų9638.7 Ų38.742%0.41719%0.188SC..Hα-helixtrans-65.8-37.5177.7-179.6-177.7179.9179.70112.6E216 D217 L218 T223 R224E216-K220 WeakPolarHBondContact O-CB 3.35Å; E216-K220 PolarHBondContact O-N 3Å; D217-K220 WeakPolarHBondContact O-CB 3.47Å; D217-K220 PolarHBondContact O-N 3.17Å; L218-K220 VanDerWaalsContact C-N 3.29Å; L218-K220 PolarHBondContact O-N 2.68Å; K220-T223 WeakPolarHBondContact CA-OG1 3.26Å; K220-T223 PolarHBondContact O-OG1 2.82Å; K220-T223 VanDerWaalsContact O-OG1 3.14Å; K220-R224 WeakPolarHBondContact O-CB 3.25Å; K220-R224 WeakPolarHBondContact O-CD 3.19Å; K220-R224 WeakPolarHBondContact O-CG 3.28Å; K220-R224 PolarHBondContact O-N 2.9Å
221V91.7Very high93.4Very high10 Ų1037.2 Ų37.26%0.06119%0.185CC..Hα-helixtrans-67.9-50.2176.3170.70000110D217 L218 T223 R224 G225 G226 I228 I339 R341D217-V221 WeakPolarHBondContact O-CG2 3.38Å; D217-V221 PolarHBondContact O-N 2.94Å; L218-V221 PolarHBondContact O-N 3.11Å; V221-T223 PolarHBondContact O-N 2.67Å; V221-R224 CarbonylContact O-C 3.43Å; V221-R224 PolarHBondContact O-N 2.88Å; V221-R224 VanDerWaalsContact O-N 3.08Å; V221-G225 PolarHBondContact O-N 2.78Å; V221-G226 WeakPolarHBondContact O-CA 3.42Å; V221-G226 PolarHBondContact O-N 2.92Å; V221-I228 HydrophobicContact CB-CD1 4.42Å; V221-I228 HydrophobicContact CG1-CD1 4.27Å; V221-I228 HydrophobicContact CG1-CG1 4.19Å; V221-I339 HydrophobicContact CB-CG2 4.15Å; V221-I339 HydrophobicContact CG1-CG2 3.78Å; V221-I339 HydrophobicContact CG2-CG2 3.83Å; V221-R341 HydrophobicContact CG1-CG 4.22Å; V221-R341 HydrophobicContact CG2-CG 4.01Å
222H92Very high93.3Very high31 Ų3136.8 Ų36.814%0.14418%0.183CC..Hα-helixtrans-58-48.7179.2-175.3-89.8000112.1L218 R224 G225 I228 T257 I259L218-H222 WeakPolarHBondContact O-CB 3.41Å; L218-H222 PolarHBondContact O-N 2.81Å; H222-R224 PolarHBondContact O-N 2.97Å; H222-R224 VanDerWaalsContact O-N 3.09Å; H222-G225 PolarHBondContact O-N 2.89Å; H222-I228 HydrophobicContact CB-CD1 4.2Å; H222-T257 PolarHBondContact NE2-O 2.87Å; H222-I259 HydrophobicContact CB-CD1 4.01Å; H222-I259 HydrophobicContact CB-CG1 4.45Å
223T90.2Very high93Very high94 Ų9437.1 Ų37.158%0.57719%0.188SC*.THydrogen-bonded Turntrans-63.3-17.2178.150.80000114.3L219 K220 V221L219-T223 HydrophobicContact CD1-CG2 3.95Å; L219-T223 HydrophobicContact CG-CG2 4.44Å; L219-T223 WeakPolarHBondContact O-CB 3.21Å; L219-T223 VanDerWaalsContact O-CG2 3.22Å; L219-T223 WeakPolarHBondContact O-CG2 3.4Å; L219-T223 PolarHBondContact O-N 3.48Å; L219-T223 PolarHBondContact O-OG1 3.05Å; K220-T223 WeakPolarHBondContact CA-OG1 3.26Å; K220-T223 PolarHBondContact O-OG1 2.82Å; K220-T223 VanDerWaalsContact O-OG1 3.14Å; V221-T223 PolarHBondContact O-N 2.67Å
224R88.3Confident92.1Very high123 Ų12332.1 Ų32.146%0.46417%0.169SC..THydrogen-bonded Turntrans-99.814.1176.4-67.7175-179.4-152.5-6.4112.9K220 V221 H222 G226K220-R224 WeakPolarHBondContact O-CB 3.25Å; K220-R224 WeakPolarHBondContact O-CD 3.19Å; K220-R224 WeakPolarHBondContact O-CG 3.28Å; K220-R224 PolarHBondContact O-N 2.9Å; V221-R224 CarbonylContact O-C 3.43Å; V221-R224 PolarHBondContact O-N 2.88Å; V221-R224 VanDerWaalsContact O-N 3.08Å; H222-R224 PolarHBondContact O-N 2.97Å; H222-R224 VanDerWaalsContact O-N 3.09Å; R224-G226 VanDerWaalsContact C-N 3.28Å; R224-G226 PolarHBondContact O-N 3.31Å
225G89.3Confident90.8Very high12 Ų1238.3 Ų38.312%0.12421%0.213CC..THydrogen-bonded Turntrans75.414.4-179.100000113.9V221 H222 I342V221-G225 PolarHBondContact O-N 2.78Å; H222-G225 PolarHBondContact O-N 2.89Å; G225-I342 VanDerWaalsContact O-CG1 3.31Å; G225-I342 WeakPolarHBondContact O-CG1 3.42Å
226G92Very high89Confident4 Ų444.1 Ų44.14%0.04125%0.245CC..  trans-69.7150.3168.600000111.2V221 R224 C340V221-G226 WeakPolarHBondContact O-CA 3.42Å; V221-G226 PolarHBondContact O-N 2.92Å; R224-G226 VanDerWaalsContact C-N 3.28Å; R224-G226 PolarHBondContact O-N 3.31Å; G226-C340 CarbonylContact C-O 3.54Å; G226-C340 WeakPolarHBondContact CA-O 3.36Å
227L94.6Very high87Confident6 Ų643.7 Ų43.73%0.03126%0.26CS..EExtended strand (participates in β ladder)trans-106.2140.7-177.1-61.5-176.5000109.2C89 Q93 L96 I186 T190 C340C89-L227 HydrophobicContact CB-CB 4.08Å; C89-L227 HydrophobicContact CB-CD1 4.08Å; C89-L227 HydrophobicContact CB-CD2 4.08Å; C89-L227 HydrophobicContact CB-CG 4.3Å; C89-L227 WeakPolarHBondContact O-CD2 3.47Å; Q93-L227 HydrophobicContact CG-CD2 3.66Å; L96-L227 HydrophobicContact CD1-CD1 4.29Å; I186-L227 HydrophobicContact CD1-CB 4.23Å; I186-L227 HydrophobicContact CG2-CB 3.91Å; I186-L227 HydrophobicContact CG2-CD1 3.83Å; I186-L227 HydrophobicContact CG2-CG 4.42Å; T190-L227 HydrophobicContact CG2-CD1 3.99Å; L227-C340 HydrophobicContact CB-CB 4.32Å; L227-C340 PolarHBondContact N-O 3.35Å; L227-C340 WeakPolarHBondContact O-CA 3.28Å; L227-C340 VanDerWaalsContact O-CB 3.31Å; L227-C340 WeakPolarHBondContact O-CB 3.47Å; L227-C340 PolarHBondContact O-N 2.88Å
228I95.6Very high85.1Confident1 Ų144 Ų441%0.00527%0.266CS..EExtended strand (participates in β ladder)trans-135.9129.5-174.3-55.6163.8000108.4C89 L218 V221 H222 V256 I259 V337 D338 I339C89-I228 PolarHBondContact SG-O 2.82Å; C89-I228 VanDerWaalsContact SG-O 3.39Å; L218-I228 HydrophobicContact CB-CD1 4.13Å; L218-I228 HydrophobicContact CD2-CD1 4.03Å; L218-I228 HydrophobicContact CD2-CG2 4.26Å; V221-I228 HydrophobicContact CB-CD1 4.42Å; V221-I228 HydrophobicContact CG1-CD1 4.27Å; V221-I228 HydrophobicContact CG1-CG1 4.19Å; H222-I228 HydrophobicContact CB-CD1 4.2Å; I228-V256 HydrophobicContact CB-CB 3.94Å; I228-V256 HydrophobicContact CB-CG2 4.05Å; I228-V256 HydrophobicContact CG2-CB 4.06Å; I228-V256 HydrophobicContact CG2-CG2 3.6Å; I228-V256 WeakPolarHBondContact O-CB 3.43Å; I228-V256 PolarHBondContact O-N 2.74Å; I228-I259 HydrophobicContact CD1-CD1 3.8Å; I228-V337 HydrophobicContact CG2-CG2 3.54Å; I228-D338 WeakPolarHBondContact CA-O 3.45Å; I228-I339 HydrophobicContact CG1-CG2 4.48Å
229S95.6Very high83.2Confident1 Ų148.1 Ų48.11%0.00730%0.3CS..EExtended strand (participates in β ladder)trans-123.4157.5170.551.50000109.9A182 Y254 V337 D338A182-S229 WeakPolarHBondContact CB-OG 3.3Å; S229-Y254 CarbonylContact C-O 3.44Å; S229-Y254 VanDerWaalsContact CA-O 3.22Å; S229-Y254 WeakPolarHBondContact CA-O 3.36Å; S229-Y254 WeakPolarHBondContact CB-O 3.46Å; S229-V337 WeakPolarHBondContact O-CG2 3.49Å; S229-D338 PolarHBondContact N-O 3.24Å; S229-D338 PolarHBondContact O-N 2.87Å; S229-D338 WeakPolarHBondContact OG-CB 3.44Å
230C95.8Very high81.9Confident2 Ų252.9 Ų52.91%0.01433%0.326CS..EExtended strand (participates in β ladder)trans-144.6160.3177.857.80000110.9Y254 L282 W330 F334 D336 V337C230-Y254 PolarHBondContact N-O 2.75Å; C230-Y254 PolarHBondContact O-N 3.17Å; C230-L282 VanDerWaalsContact SG-CD2 3.57Å; C230-W330 HydrophobicContact CB-CZ2 3.81Å; C230-F334 HydrophobicContact CB-CD1 3.94Å; C230-F334 HydrophobicContact CB-CE1 4.4Å; C230-F334 VanDerWaalsContact SG-CE1 3.54Å; C230-D336 VanDerWaalsContact CA-O 3.25Å; C230-D336 WeakPolarHBondContact CA-O 3.29Å; C230-D336 VanDerWaalsContact CB-O 3.27Å; C230-D336 WeakPolarHBondContact CB-O 3.48Å; C230-V337 HydrophobicContact CB-CB 4.34Å; C230-V337 HydrophobicContact CB-CG2 4.34Å
231S94.1Very high81.3Confident30 Ų3052.3 Ų52.321%0.2133%0.325CS..EExtended strand (participates in β ladder)trans-145.6165.8-178.554.30000112H252 T335 D336S231-H252 WeakPolarHBondContact CA-O 3.14Å; S231-H252 VanDerWaalsContact CB-O 3.3Å; S231-H252 WeakPolarHBondContact CB-O 3.27Å; S231-T335 PolarHBondContact O-N 2.89Å; S231-T335 VanDerWaalsContact O-N 3.14Å; S231-T335 PolarHBondContact O-OG1 3.08Å; S231-D336 PolarHBondContact N-O 3.44Å; S231-D336 PolarHBondContact O-N 3.03Å
232I92.1Very high80.9Confident13 Ų1357.2 Ų57.27%0.06735%0.348CS..  trans-117.7110.1174.2-52.1171.5000107.1L248 I250 G251 F334 T335I232-L248 HydrophobicContact CD1-CB 3.65Å; I232-L248 HydrophobicContact CD1-CD1 3.96Å; I232-L248 HydrophobicContact CD1-CG 4.36Å; I232-I250 HydrophobicContact CG2-CB 4.41Å; I232-I250 HydrophobicContact CG2-CG1 3.93Å; I232-I250 HydrophobicContact CG2-CG2 4.37Å; I232-G251 PolarHBondContact O-N 3.14Å; I232-F334 HydrophobicContact CD1-CD1 4.4Å; I232-F334 HydrophobicContact CD1-CE1 4.17Å; I232-F334 HydrophobicContact CD1-CZ 4.26Å; I232-F334 HydrophobicContact CG1-CD1 3.71Å; I232-F334 HydrophobicContact CG1-CE1 3.88Å; I232-F334 HydrophobicContact CG1-CG 4.13Å; I232-F334 HydrophobicContact CG1-CZ 4.42Å; I232-T335 HydrophobicContact CG2-CG2 4.36Å
233T85.5Confident80.8Confident77 Ų7759.9 Ų59.947%0.47236%0.361SS..  trans-90133.9-179.4-58.60000109.6T335 D336T233-T335 WeakPolarHBondContact CB-OG1 3.47Å; T233-T335 PolarHBondContact N-OG1 2.88Å; T233-T335 PolarHBondContact OG1-OG1 3.21Å; T233-D336 PolarHBondContact OG1-OD2 2.63Å
234A76Confident80.7Confident15 Ų1557.4 Ų57.412%0.12435%0.346CS..  trans-69.3134.9-179.500000111.7N236 G237 S238 I250A234-N236 WeakPolarHBondContact CB-OD1 3.29Å; A234-N236 PolarHBondContact O-N 3.16Å; A234-N236 VanDerWaalsContact O-N 3.09Å; A234-G237 PolarHBondContact O-N 3.38Å; A234-S238 VanDerWaalsContact CB-O 3.24Å; A234-S238 WeakPolarHBondContact CB-O 3.31Å; A234-I250 HydrophobicContact CB-CG2 3.6Å
235S66.9Low80.6Confident139 Ų13960.8 Ų60.897%0.97237%0.367SS*.THydrogen-bonded Turntrans-61.4-21.3-178.6-34.80000114.3
236N58.1Low80.6Confident123 Ų12363.7 Ų63.766%0.65838%0.378SS*.THydrogen-bonded Turntrans-101.55.8-179.261.1-2000113.2A234 S238A234-N236 WeakPolarHBondContact CB-OD1 3.29Å; A234-N236 PolarHBondContact O-N 3.16Å; A234-N236 VanDerWaalsContact O-N 3.09Å; N236-S238 PolarHBondContact ND2-OG 3.05Å; N236-S238 PolarHBondContact O-N 3.29Å; N236-S238 VanDerWaalsContact O-N 3.16Å; N236-S238 WeakPolarHBondContact OD1-CB 3.43Å; N236-S238 PolarHBondContact OD1-N 3.1Å; N236-S238 VanDerWaalsContact OD1-N 3.1Å; N236-S238 PolarHBondContact OD1-OG 3.09Å
237G53.8Low80.5Confident67 Ų6763.5 Ų63.569%0.69138%0.376SS*.  trans66.88.8-176.600000114.6A234 A239A234-G237 PolarHBondContact O-N 3.38Å; G237-A239 PolarHBondContact O-N 2.81Å
238S52.8Low80.4Confident51 Ų5163.2 Ų63.236%0.35738%0.375SS..  trans-71.8122.7173.474.30000109.4A234 N236 N240A234-S238 VanDerWaalsContact CB-O 3.24Å; A234-S238 WeakPolarHBondContact CB-O 3.31Å; N236-S238 PolarHBondContact ND2-OG 3.05Å; N236-S238 PolarHBondContact O-N 3.29Å; N236-S238 VanDerWaalsContact O-N 3.16Å; N236-S238 WeakPolarHBondContact OD1-CB 3.43Å; N236-S238 PolarHBondContact OD1-N 3.1Å; N236-S238 VanDerWaalsContact OD1-N 3.1Å; N236-S238 PolarHBondContact OD1-OG 3.09Å; S238-N240 PolarHBondContact O-N 3.16Å
239A55.2Low80.2Confident88 Ų8863.2 Ų63.273%0.72737%0.374SS*.  trans-81.49.3-177.600000113.5G237G237-A239 PolarHBondContact O-N 2.81Å
240N67.3Low79.9Confident128 Ų12864.6 Ų64.668%0.68438%0.381SS*.  trans-81.4128.7-175.2-70.6-11.6000110.4S238 M242S238-N240 PolarHBondContact O-N 3.16Å; N240-M242 PolarHBondContact O-N 2.79Å
241E79.6Confident79.4Confident83 Ų8366.1 Ų66.139%0.38840%0.397SS..  trans-61.2117.8175.9-66170.2159.600110V249 I250 H252 W286E241-V249 HydrophobicContact CB-CG1 4.15Å; E241-I250 VanDerWaalsContact CA-O 3.26Å; E241-I250 WeakPolarHBondContact CA-O 3.25Å; E241-H252 IonicContact OE1-ND1 3.74Å; E241-W286 HydrophobicContact CB-CH2 4.3Å; E241-W286 HydrophobicContact CB-CZ2 4.32Å; E241-W286 HydrophobicContact CG-CZ2 4.41Å; E241-W286 WeakPolarHBondContact OE2-CZ2 3.39Å
242M85.3Confident79.1Confident114 Ų11464.8 Ų64.856%0.56239%0.388SS*.EExtended strand (participates in β ladder)trans-133.7127.7-177.3-174.7175.670.700111.1N240 V249 I250N240-M242 PolarHBondContact O-N 2.79Å; M242-V249 CarbonylContact O-C 3.46Å; M242-V249 WeakPolarHBondContact O-CA 3.4Å; M242-I250 HydrophobicContact CE-CD1 3.85Å; M242-I250 PolarHBondContact N-O 3.28Å; M242-I250 PolarHBondContact O-N 3.36Å
243E88.3Confident79Confident86 Ų8664.6 Ų64.640%0.40239%0.389SS..EExtended strand (participates in β ladder)trans-78.2133.2175.9-171.3171.1178.100111.3L248 R289E243-L248 CarbonylContact C-O 3.44Å; E243-L248 WeakPolarHBondContact CA-O 3.19Å; E243-R289 VanDerWaalsContact OE2-CD 3.26Å; E243-R289 WeakPolarHBondContact OE2-CD 3.26Å; E243-R289 IonicContact OE2-CZ 2.67Å; E243-R289 IonicContact OE2-NE 3.48Å; E243-R289 PolarHBondContact OE2-NE 2.86Å; E243-R289 IonicContact OE2-NH1 2.81Å; E243-R289 PolarHBondContact OE2-NH1 3.27Å
244T88.6Confident79.4Confident42 Ų4261 Ų6126%0.25837%0.366SS..  trans-83.5162.8174.764.60000111M246 G247 L248 I250T244-M246 PolarHBondContact O-N 2.89Å; T244-M246 PolarHBondContact OG1-N 3.36Å; T244-G247 PolarHBondContact O-N 3.39Å; T244-L248 WeakPolarHBondContact CB-O 3.31Å; T244-L248 WeakPolarHBondContact CG2-O 3.34Å; T244-L248 PolarHBondContact N-O 3.25Å; T244-L248 PolarHBondContact OG1-N 2.76Å; T244-L248 VanDerWaalsContact OG1-N 3.11Å; T244-L248 PolarHBondContact OG1-O 3.33Å; T244-I250 HydrophobicContact CG2-CD1 3.9Å; T244-I250 HydrophobicContact CG2-CG1 3.75Å
245E87.2Confident80.2Confident195 Ų19560.2 Ų60.291%0.91136%0.36SS*.THydrogen-bonded Turntrans-57.6-23.8173.4-62.2-178.917500112.9
246M89.1Confident81.5Confident72 Ų7253.7 Ų53.736%0.35532%0.315SS..THydrogen-bonded Turntrans-90.35.6179.5-57.7-61.2-70.200113.7T244 L248 W291 N292T244-M246 PolarHBondContact O-N 2.89Å; T244-M246 PolarHBondContact OG1-N 3.36Å; M246-L248 VanDerWaalsContact C-N 3.31Å; M246-L248 PolarHBondContact O-N 3.47Å; M246-W291 HydrophobicContact CB-CE3 3.89Å; M246-W291 HydrophobicContact CB-CH2 4.3Å; M246-W291 HydrophobicContact CB-CZ3 3.49Å; M246-W291 VanDerWaalsContact CB-CZ3 3.49Å; M246-W291 HydrophobicContact CE-CE3 4.48Å; M246-W291 HydrophobicContact CE-CH2 3.4Å; M246-W291 VanDerWaalsContact CE-CH2 3.4Å; M246-W291 HydrophobicContact CE-CZ2 3.83Å; M246-W291 HydrophobicContact CE-CZ3 3.79Å; M246-W291 HydrophobicContact CG-CH2 4.41Å; M246-W291 HydrophobicContact CG-CZ3 4.02Å; M246-N292 PolarHBondContact O-N 3.48Å
247G89.8Confident83.1Confident0 Ų048.2 Ų48.20%029%0.285CS..SBendtrans83.7-5.5177.800000115.5T244 E290T244-G247 PolarHBondContact O-N 3.39Å; G247-E290 WeakPolarHBondContact CA-O 3.48Å
248L92.5Very high85Confident1 Ų145.2 Ų45.21%0.00525%0.254CS..  trans-76.3155.3172.7-57.4175.7000111.2I232 E243 T244 M246 W291 F323 M325 N333 F334I232-L248 HydrophobicContact CD1-CB 3.65Å; I232-L248 HydrophobicContact CD1-CD1 3.96Å; I232-L248 HydrophobicContact CD1-CG 4.36Å; E243-L248 CarbonylContact C-O 3.44Å; E243-L248 WeakPolarHBondContact CA-O 3.19Å; T244-L248 WeakPolarHBondContact CB-O 3.31Å; T244-L248 WeakPolarHBondContact CG2-O 3.34Å; T244-L248 PolarHBondContact N-O 3.25Å; T244-L248 PolarHBondContact OG1-N 2.76Å; T244-L248 VanDerWaalsContact OG1-N 3.11Å; T244-L248 PolarHBondContact OG1-O 3.33Å; M246-L248 VanDerWaalsContact C-N 3.31Å; M246-L248 PolarHBondContact O-N 3.47Å; L248-W291 HydrophobicContact CD1-CE3 3.85Å; L248-W291 HydrophobicContact CD1-CZ3 3.87Å; L248-W291 HydrophobicContact CD2-CB 4.47Å; L248-W291 HydrophobicContact CD2-CE3 4.22Å; L248-W291 HydrophobicContact CG-CE3 3.89Å; L248-W291 HydrophobicContact CG-CZ3 4.32Å; L248-F323 HydrophobicContact CD2-CE2 3.9Å; L248-F323 HydrophobicContact CD2-CZ 3.61Å; L248-M325 HydrophobicContact CD1-CE 4.47Å; L248-N333 HydrophobicContact CD1-CB 3.7Å; L248-F334 HydrophobicContact CD1-CE2 4.01Å; L248-F334 HydrophobicContact CD1-CZ 4.45Å; L248-F334 HydrophobicContact CD2-CE2 4.4Å; L248-F334 HydrophobicContact CD2-CZ 4.24Å
249V90.1Very high87Confident0 Ų042.8 Ų42.80%024%0.237CC..EExtended strand (participates in β ladder)trans-114.5123.8-177.3-174.30000109.8E241 M242 H252 Y254 W286E241-V249 HydrophobicContact CB-CG1 4.15Å; M242-V249 CarbonylContact O-C 3.46Å; M242-V249 WeakPolarHBondContact O-CA 3.4Å; V249-H252 HydrophobicContact CB-CB 3.89Å; V249-H252 HydrophobicContact CG1-CB 3.73Å; V249-Y254 WeakPolarHBondContact CB-OH 3.04Å; V249-Y254 WeakPolarHBondContact CG2-OH 3.37Å; V249-Y254 PolarHBondContact N-OH 3.27Å; V249-W286 HydrophobicContact CG1-CH2 3.69Å; V249-W286 HydrophobicContact CG1-CZ2 4.33Å; V249-W286 HydrophobicContact CG1-CZ3 4.15Å; V249-W286 HydrophobicContact CG2-CE3 4.28Å; V249-W286 HydrophobicContact CG2-CH2 4.09Å; V249-W286 HydrophobicContact CG2-CZ3 3.66Å
250I89.4Confident88.7Confident30 Ų3043.3 Ų43.315%0.15422%0.221CC..EExtended strand (participates in β ladder)trans-78.1145.3172.9-55-178.6000109I232 A234 E241 M242 T244 H252I232-I250 HydrophobicContact CG2-CB 4.41Å; I232-I250 HydrophobicContact CG2-CG1 3.93Å; I232-I250 HydrophobicContact CG2-CG2 4.37Å; A234-I250 HydrophobicContact CB-CG2 3.6Å; E241-I250 VanDerWaalsContact CA-O 3.26Å; E241-I250 WeakPolarHBondContact CA-O 3.25Å; M242-I250 HydrophobicContact CE-CD1 3.85Å; M242-I250 PolarHBondContact N-O 3.28Å; M242-I250 PolarHBondContact O-N 3.36Å; T244-I250 HydrophobicContact CG2-CD1 3.9Å; T244-I250 HydrophobicContact CG2-CG1 3.75Å; I250-H252 VanDerWaalsContact C-N 3.31Å
251G85.5Confident89.9Confident34 Ų3440.8 Ų40.835%0.35120%0.203SC..THydrogen-bonded Turntrans78.215.4-177.800000113.6I232I232-G251 PolarHBondContact O-N 3.14Å
252H87.3Confident90.2Very high2 Ų236.9 Ų36.91%0.00919%0.185CC..  trans-127.7146.7-169.4-168.855.5000112.9C81 S231 E241 V249 I250 Y254 N284 P285 W286C81-H252 WeakPolarHBondContact CB-CE1 3.1Å; C81-H252 WeakPolarHBondContact CB-ND1 3.39Å; S231-H252 WeakPolarHBondContact CA-O 3.14Å; S231-H252 VanDerWaalsContact CB-O 3.3Å; S231-H252 WeakPolarHBondContact CB-O 3.27Å; E241-H252 IonicContact OE1-ND1 3.74Å; V249-H252 HydrophobicContact CB-CB 3.89Å; V249-H252 HydrophobicContact CG1-CB 3.73Å; I250-H252 VanDerWaalsContact C-N 3.31Å; H252-Y254 HydrophobicContact CB-CE2 4.25Å; H252-Y254 AromaticContact CD2-CE2 3.76Å; H252-Y254 AromaticContact CD2-CZ 3.84Å; H252-N284 PolarHBondContact NE2-OD1 2.92Å; H252-P285 WeakPolarHBondContact NE2-CD 3.49Å; H252-W286 AromaticContact CE1-CD1 3.7Å; H252-W286 AromaticContact CE1-CE2 3.73Å; H252-W286 AromaticContact CE1-NE1 3.33Å; H252-W286 PolarHBondContact CE1-NE1 2.62Å; H252-W286 VanDerWaalsContact CE1-NE1 3.33Å; H252-W286 AromaticContact NE2-CD1 4Å; H252-W286 AromaticContact NE2-NE1 3.91Å
253A90.9Very high89.9Confident10 Ų1039.5 Ų39.58%0.08319%0.189CC..EExtended strand (participates in β ladder)trans-94.1134.1177.300000111.4W82 A85 A182 P285W82-A253 HydrophobicContact CB-CB 4.44Å; A85-A253 HydrophobicContact CB-CB 3.84Å; A182-A253 HydrophobicContact CB-CB 4.43Å; A253-P285 WeakPolarHBondContact O-CD 3.38Å; A253-P285 WeakPolarHBondContact O-CG 3.17Å
254Y93.2Very high89.3Confident0 Ų037.8 Ų37.80%018%0.182CC..EExtended strand (participates in β ladder)trans-115147.6174.6-70.4-97.6000110.3S229 C230 V249 H252 N284 F323 F334S229-Y254 CarbonylContact C-O 3.44Å; S229-Y254 VanDerWaalsContact CA-O 3.22Å; S229-Y254 WeakPolarHBondContact CA-O 3.36Å; S229-Y254 WeakPolarHBondContact CB-O 3.46Å; C230-Y254 PolarHBondContact N-O 2.75Å; C230-Y254 PolarHBondContact O-N 3.17Å; V249-Y254 WeakPolarHBondContact CB-OH 3.04Å; V249-Y254 WeakPolarHBondContact CG2-OH 3.37Å; V249-Y254 PolarHBondContact N-OH 3.27Å; H252-Y254 HydrophobicContact CB-CE2 4.25Å; H252-Y254 AromaticContact CD2-CE2 3.76Å; H252-Y254 AromaticContact CD2-CZ 3.84Å; Y254-N284 HydrophobicContact CD1-CB 4.16Å; Y254-N284 HydrophobicContact CE1-CB 3.74Å; Y254-F323 HydrophobicContact CD1-CE1 4.2Å; Y254-F323 HydrophobicContact CD1-CZ 4.11Å; Y254-F323 AromaticContact CE1-CE1 3.95Å; Y254-F323 HydrophobicContact CE1-CE1 3.95Å; Y254-F323 AromaticContact CE1-CZ 3.95Å; Y254-F323 HydrophobicContact CE1-CZ 3.95Å; Y254-F334 AromaticContact CD2-CE1 3.76Å; Y254-F334 HydrophobicContact CD2-CE1 3.76Å; Y254-F334 HydrophobicContact CD2-CZ 4.25Å; Y254-F334 HydrophobicContact CE2-CE1 4.36Å; Y254-F334 HydrophobicContact CG-CE1 4.09Å; Y254-F334 HydrophobicContact CG-CZ 4.36Å
255S93.5Very high88.1Confident0 Ų038.1 Ų38.10%019%0.194CC..EExtended strand (participates in β ladder)trans-97.4133.1175.6-53.20000110.1A85 S88 T257 L282 R283A85-S255 VanDerWaalsContact CA-OG 3.29Å; A85-S255 WeakPolarHBondContact CA-OG 3.36Å; A85-S255 PolarHBondContact O-OG 2.91Å; S88-S255 WeakPolarHBondContact CB-OG 3.35Å; S255-T257 PolarHBondContact O-N 2.97Å; S255-L282 CarbonylContact O-C 3.45Å; S255-L282 VanDerWaalsContact O-CA 3.23Å; S255-L282 WeakPolarHBondContact O-CA 3.39Å; S255-R283 PolarHBondContact N-O 3.06Å; S255-R283 PolarHBondContact O-N 2.94Å
256V94.8Very high86.5Confident2 Ų238.7 Ų38.71%0.01220%0.197CC..EExtended strand (participates in β ladder)trans-86.4111.6171.6-178.80000109I228 I259 I280 R281 L282I228-V256 HydrophobicContact CB-CB 3.94Å; I228-V256 HydrophobicContact CB-CG2 4.05Å; I228-V256 HydrophobicContact CG2-CB 4.06Å; I228-V256 HydrophobicContact CG2-CG2 3.6Å; I228-V256 WeakPolarHBondContact O-CB 3.43Å; I228-V256 PolarHBondContact O-N 2.74Å; V256-I259 HydrophobicContact CG1-CD1 4.06Å; V256-I259 HydrophobicContact CG1-CG1 3.76Å; V256-I280 HydrophobicContact CG1-CD1 3.81Å; V256-I280 HydrophobicContact CG1-CG1 3.75Å; V256-I280 HydrophobicContact CG2-CD1 4.02Å; V256-R281 WeakPolarHBondContact CA-O 3.35Å; V256-L282 HydrophobicContact CB-CD2 4.32Å; V256-L282 HydrophobicContact CG2-CD2 3.66Å
257T92.1Very high84.5Confident7 Ų746.3 Ų46.34%0.04322%0.221CC..EExtended strand (participates in β ladder)trans-95.9-27.2-175.867.60000112.7L92 H222 S255 R281 R283 E322L92-T257 HydrophobicContact CD1-CG2 4.11Å; H222-T257 PolarHBondContact NE2-O 2.87Å; S255-T257 PolarHBondContact O-N 2.97Å; T257-R281 PolarHBondContact N-O 3.27Å; T257-R281 PolarHBondContact OG1-NE 2.75Å; T257-R283 HydrophobicContact CG2-CB 3.75Å; T257-E322 VanDerWaalsContact CB-OE1 3.24Å; T257-E322 WeakPolarHBondContact CB-OE1 3.25Å; T257-E322 WeakPolarHBondContact CG2-OE1 3.39Å; T257-E322 PolarHBondContact OG1-OE1 2.76Å
258A92.3Very high82.2Confident5 Ų554 Ų544%0.04126%0.262CS..EExtended strand (participates in β ladder)trans-150.7149.8174.500000113.7I280 R281 W324A258-I280 WeakPolarHBondContact O-CA 3.36Å; A258-R281 HydrophobicContact CB-CB 3.84Å; A258-R281 PolarHBondContact N-O 2.78Å; A258-R281 PolarHBondContact O-N 2.79Å; A258-W324 HydrophobicContact CB-CH2 3.64Å; A258-W324 HydrophobicContact CB-CZ2 4.14Å; A258-W324 HydrophobicContact CB-CZ3 4.39Å
259I94.6Very high79.8Confident0 Ų060.3 Ų60.30%029%0.294CS..EExtended strand (participates in β ladder)trans-132.8124171.6-55.6175.8000107.9F215 L218 L219 H222 I228 V256 I280F215-I259 HydrophobicContact CD2-CG2 4.04Å; F215-I259 HydrophobicContact CE2-CG2 3.42Å; F215-I259 VanDerWaalsContact CE2-CG2 3.42Å; F215-I259 HydrophobicContact CZ-CG2 3.79Å; L218-I259 HydrophobicContact CB-CD1 3.53Å; L219-I259 HydrophobicContact CB-CG2 3.93Å; L219-I259 HydrophobicContact CD1-CB 4.18Å; L219-I259 HydrophobicContact CD1-CG2 4.04Å; L219-I259 VanDerWaalsContact CD1-O 3.3Å; L219-I259 WeakPolarHBondContact CD1-O 3.36Å; H222-I259 HydrophobicContact CB-CD1 4.01Å; H222-I259 HydrophobicContact CB-CG1 4.45Å; I228-I259 HydrophobicContact CD1-CD1 3.8Å; V256-I259 HydrophobicContact CG1-CD1 4.06Å; V256-I259 HydrophobicContact CG1-CG1 3.76Å; I259-I280 HydrophobicContact CG1-CG1 4.29Å
260R92.3Very high77.3Confident99 Ų9968.5 Ų68.537%0.37434%0.337SS..EExtended strand (participates in β ladder)trans-143146.8-171.6-64-65.4-179.7-94.80.8112.7V262 M279 L313 W324R260-V262 HydrophobicContact CB-CG2 4.39Å; R260-M279 PolarHBondContact N-O 3.29Å; R260-M279 PolarHBondContact O-N 3.3Å; R260-L313 HydrophobicContact CB-CD2 3.92Å; R260-L313 HydrophobicContact CG-CD2 3.85Å; R260-W324 HydrophobicContact CB-CH2 4.22Å; R260-W324 HydrophobicContact CB-CZ3 4.33Å; R260-W324 HydrophobicContact CG-CH2 3.79Å; R260-W324 HydrophobicContact CG-CZ3 4.35Å
261K91.2Very high75.1Confident74 Ų7471 Ų7132%0.32236%0.357SS..EExtended strand (participates in β ladder)trans-95.2110.6164.9-63.4178.8-176.41710107.5F215 E216 L219 L277 F278F215-K261 HydrophobicContact CE1-CD 4.29Å; F215-K261 HydrophobicContact CE1-CG 3.66Å; F215-K261 HydrophobicContact CZ-CG 3.96Å; E216-K261 VanDerWaalsContact OE1-CE 3.27Å; E216-K261 WeakPolarHBondContact OE1-CE 3.38Å; E216-K261 IonicContact OE1-NZ 3.36Å; E216-K261 PolarHBondContact OE1-NZ 2.63Å; E216-K261 IonicContact OE2-NZ 3.05Å; E216-K261 PolarHBondContact OE2-NZ 2.9Å; L219-K261 HydrophobicContact CD2-CD 4.44Å; L219-K261 HydrophobicContact CD2-CG 4.47Å; K261-L277 CarbonylContact C-O 3.6Å; K261-L277 WeakPolarHBondContact CA-O 3.27Å; K261-F278 HydrophobicContact CD-CE1 4.19Å; K261-F278 HydrophobicContact CG-CD1 3.94Å; K261-F278 HydrophobicContact CG-CE1 4.01Å
262V86.4Confident73.1Confident1 Ų179.9 Ų79.91%0.00639%0.386CS..EExtended strand (participates in β ladder)trans-97.3139.7-178.8-1770000109.3R260 K276 L277 M279 V305 E309 L313R260-V262 HydrophobicContact CB-CG2 4.39Å; V262-K276 WeakPolarHBondContact O-CA 3.27Å; V262-L277 HydrophobicContact CB-CB 4.42Å; V262-L277 PolarHBondContact N-O 3.14Å; V262-L277 PolarHBondContact O-N 3.47Å; V262-M279 HydrophobicContact CB-CG 4.2Å; V262-M279 HydrophobicContact CG2-CB 4.08Å; V262-M279 HydrophobicContact CG2-CG 3.61Å; V262-V305 HydrophobicContact CG1-CG1 4.35Å; V262-V305 HydrophobicContact CG1-CG2 4.24Å; V262-E309 HydrophobicContact CG1-CG 4.1Å; V262-L313 HydrophobicContact CG1-CD1 4.23Å; V262-L313 HydrophobicContact CG2-CD1 3.79Å; V262-L313 HydrophobicContact CG2-CD2 3.89Å; V262-L313 HydrophobicContact CG2-CG 4.46Å
263R79.6Confident71.1Confident170 Ų17088.8 Ų88.864%0.64243%0.425SS*.EExtended strand (participates in β ladder)trans-97.5127.5172.3-64.7-178.1-175.5175.40.6108.8
264L75.3Confident69.3Low50 Ų5091.8 Ų91.826%0.26245%0.45SS..PPolyproline II helixtrans-77.5143.3170.4-60.7173.7000109.1L277 W295 K304 V305L264-L277 HydrophobicContact CD2-CD2 4.41Å; L264-W295 HydrophobicContact CD2-CH2 3.74Å; L264-W295 HydrophobicContact CD2-CZ2 4.24Å; L264-K304 HydrophobicContact CD2-CB 4.43Å; L264-V305 HydrophobicContact CD2-CG2 4.01Å
265G62.9Low67.9Low49 Ų4998.6 Ų98.651%0.50548%0.482SS..PPolyproline II helixtrans-61.5162.1-161.700000117.8R267 K304G265-R267 PolarHBondContact O-N 2.7Å; G265-K304 PolarHBondContact N-O 2.8Å
266E53.8Low67.1Low207 Ų207104.7 Ų104.797%0.96751%0.508SS*.  trans-7229.3-173.6-65.6175.9151.100116.4L268E266-L268 PolarHBondContact O-N 3.18Å
267R46.8Very low66.8Low232 Ų232106.4 Ų106.488%0.87552%0.517SS*.SBendtrans-86.796.1176.2-88.2-176.2170.1179.8-2.9111.1G265G265-R267 PolarHBondContact O-N 2.7Å
268L42.2Very low66.9Low162 Ų162108.5 Ų108.585%0.84853%0.525SS*.  trans45.673154.1-85.6152.9000115.4E266E266-L268 PolarHBondContact O-N 3.18Å
269I41.9Very low67Low132 Ų132108.2 Ų108.268%0.67752%0.523SS*.  trans-121.2112.1152.8-58.3175.2000107S271I269-S271 PolarHBondContact O-N 2.76Å
270L38.1Very low67Low172 Ų172108.2 Ų108.290%0.90152%0.523SS*.  trans-66.143.7168.5-85.8152.1000111.3
271S43.7Very low67.2Low82 Ų82105.4 Ų105.457%0.57351%0.513SS*.SBendtrans-141.1121.2177.4-52.90000108.5I269 K273I269-S271 PolarHBondContact O-N 2.76Å; S271-K273 PolarHBondContact O-N 2.83Å
272F42.5Very low67.3Low222 Ų222101.9 Ų101.997%0.97450%0.497SS*.SBendtrans-69.143.6-171.2-76.2-91.2000115.4
273K44.4Very low67.5Low189 Ų189101.8 Ų101.882%0.82250%0.497SS*.  trans-143.1102.1169.6-84-176.8177.7173.50110.6S271 E275S271-K273 PolarHBondContact O-N 2.83Å; K273-E275 PolarHBondContact O-N 2.72Å
274A54.9Low68Low73 Ų7393.7 Ų93.760%0.60347%0.467SS*.PPolyproline II helixtrans-59.8121.5164.800000109.4K276A274-K276 PolarHBondContact O-N 2.93Å
275E63.1Low68.3Low143 Ų14391.3 Ų91.367%0.66845%0.454SS*.PPolyproline II helixtrans-64.3126.7172.5-71.8-175.916700109.5K273K273-E275 PolarHBondContact O-N 2.72Å
276K76.9Confident69.2Low128 Ų12891 Ų9156%0.55744%0.438SS*.EExtended strand (participates in β ladder)trans-101.8118.7175.3-67.6179.1-175.7172.20107.8V262 A274 F278V262-K276 WeakPolarHBondContact O-CA 3.27Å; A274-K276 PolarHBondContact O-N 2.93Å; K276-F278 HydrophobicContact CB-CE1 4.2Å
277L88Confident70.4Confident37 Ų3781.7 Ų81.719%0.19440%0.397CS..EExtended strand (participates in β ladder)trans-88.8131173.7-171.465.8000109.5K261 V262 L264 M279 W295 T326K261-L277 CarbonylContact C-O 3.6Å; K261-L277 WeakPolarHBondContact CA-O 3.27Å; V262-L277 HydrophobicContact CB-CB 4.42Å; V262-L277 PolarHBondContact N-O 3.14Å; V262-L277 PolarHBondContact O-N 3.47Å; L264-L277 HydrophobicContact CD2-CD2 4.41Å; L277-M279 HydrophobicContact CD2-CG 4.05Å; L277-M279 HydrophobicContact CD2-SD 3.46Å; L277-M279 WeakPolarHBondContact CD2-SD 3.31Å; L277-M279 HydrophobicContact CG-CG 4.02Å; L277-M279 HydrophobicContact CG-SD 3.73Å; L277-W295 HydrophobicContact CD2-CD2 4.25Å; L277-W295 HydrophobicContact CD2-CH2 3.85Å; L277-W295 HydrophobicContact CD2-CZ2 3.33Å; L277-W295 HydrophobicContact CD2-CZ3 4.48Å; L277-T326 HydrophobicContact CD1-CG2 4.2Å
278F93.3Very high72Confident51 Ų5175.7 Ų75.722%0.22438%0.377CS..EExtended strand (participates in β ladder)trans-93.4116.7176.8-61.3-22.3000109I212 F215 K261 K276 F327I212-F278 HydrophobicContact CG1-CE2 4.15Å; F215-F278 HydrophobicContact CD1-CB 4.36Å; F215-F278 HydrophobicContact CD1-CD1 4.16Å; F215-F278 HydrophobicContact CD1-CD2 4.19Å; F215-F278 AromaticContact CD1-CG 3.97Å; F215-F278 HydrophobicContact CD1-CG 3.97Å; F215-F278 HydrophobicContact CD2-CB 3.87Å; F215-F278 HydrophobicContact CD2-CG 4.35Å; F215-F278 HydrophobicContact CE1-CB 4.16Å; F215-F278 AromaticContact CE1-CD1 3.7Å; F215-F278 HydrophobicContact CE1-CD1 3.7Å; F215-F278 HydrophobicContact CE1-CE1 4.24Å; F215-F278 AromaticContact CE1-CG 3.86Å; F215-F278 HydrophobicContact CE1-CG 3.86Å; F215-F278 HydrophobicContact CE2-CB 3.63Å; F215-F278 HydrophobicContact CE2-CG 4.24Å; F215-F278 HydrophobicContact CG-CB 4.21Å; F215-F278 HydrophobicContact CG-CD2 4.32Å; F215-F278 HydrophobicContact CG-CG 4.21Å; F215-F278 HydrophobicContact CZ-CB 3.79Å; F215-F278 AromaticContact CZ-CD1 3.97Å; F215-F278 HydrophobicContact CZ-CD1 3.97Å; F215-F278 AromaticContact CZ-CG 4Å; F215-F278 HydrophobicContact CZ-CG 4Å; K261-F278 HydrophobicContact CD-CE1 4.19Å; K261-F278 HydrophobicContact CG-CD1 3.94Å; K261-F278 HydrophobicContact CG-CE1 4.01Å; K276-F278 HydrophobicContact CB-CE1 4.2Å; F278-F327 HydrophobicContact CB-CB 3.9Å; F278-F327 PolarHBondContact O-N 2.85Å
279M94.4Very high73.9Confident0 Ų072.8 Ų72.80%036%0.355CS..EExtended strand (participates in β ladder)trans-121.6143.5-171.2-65.7-64.7-70.900110.5R260 V262 L277 W295 W302 W324 T326R260-M279 PolarHBondContact N-O 3.29Å; R260-M279 PolarHBondContact O-N 3.3Å; V262-M279 HydrophobicContact CB-CG 4.2Å; V262-M279 HydrophobicContact CG2-CB 4.08Å; V262-M279 HydrophobicContact CG2-CG 3.61Å; L277-M279 HydrophobicContact CD2-CG 4.05Å; L277-M279 HydrophobicContact CD2-SD 3.46Å; L277-M279 WeakPolarHBondContact CD2-SD 3.31Å; L277-M279 HydrophobicContact CG-CG 4.02Å; L277-M279 HydrophobicContact CG-SD 3.73Å; M279-W295 HydrophobicContact CE-CB 3.8Å; M279-W295 HydrophobicContact CE-CD2 4.08Å; M279-W295 HydrophobicContact CE-CE3 4.26Å; M279-W295 HydrophobicContact CE-CG 3.89Å; M279-W295 HydrophobicContact SD-CD2 4.49Å; M279-W295 HydrophobicContact SD-CG 4.43Å; M279-W302 HydrophobicContact CE-CH2 3.95Å; M279-W302 HydrophobicContact CE-CZ2 4.23Å; M279-W324 HydrophobicContact CB-CE3 3.81Å; M279-W324 HydrophobicContact CB-CZ3 3.81Å; M279-W324 HydrophobicContact CE-CB 4.01Å; M279-W324 HydrophobicContact CE-CE3 4.26Å; M279-T326 HydrophobicContact SD-CG2 4.19Å
280I95.9Very high76.2Confident0 Ų067.5 Ų67.50%033%0.327CS..EExtended strand (participates in β ladder)trans-129.4138.3174.2-171.4165.7000108.9V256 A258 I259 L282 M325 F327 W330V256-I280 HydrophobicContact CG1-CD1 3.81Å; V256-I280 HydrophobicContact CG1-CG1 3.75Å; V256-I280 HydrophobicContact CG2-CD1 4.02Å; A258-I280 WeakPolarHBondContact O-CA 3.36Å; I259-I280 HydrophobicContact CG1-CG1 4.29Å; I280-L282 HydrophobicContact CD1-CD2 4.35Å; I280-L282 HydrophobicContact CG1-CD2 4.31Å; I280-M325 HydrophobicContact CG2-CG 3.8Å; I280-M325 PolarHBondContact N-O 3.49Å; I280-M325 PolarHBondContact O-N 2.9Å; I280-F327 HydrophobicContact CB-CD2 4.39Å; I280-F327 HydrophobicContact CD1-CD2 4.43Å; I280-F327 HydrophobicContact CD1-CE2 4.43Å; I280-F327 HydrophobicContact CG2-CD2 4.44Å; I280-W330 HydrophobicContact CD1-CD2 4.19Å; I280-W330 HydrophobicContact CD1-CG 4.3Å; I280-W330 HydrophobicContact CG2-CB 3.76Å; I280-W330 HydrophobicContact CG2-CG 3.92Å
281R94.9Very high78.7Confident39 Ų3959.8 Ų59.815%0.14729%0.286CS..EExtended strand (participates in β ladder)trans-110.5131.6174.9-164.8173.263.8169.318.1109.4V256 T257 A258 L313 G314 E322 F323 W324V256-R281 WeakPolarHBondContact CA-O 3.35Å; T257-R281 PolarHBondContact N-O 3.27Å; T257-R281 PolarHBondContact OG1-NE 2.75Å; A258-R281 HydrophobicContact CB-CB 3.84Å; A258-R281 PolarHBondContact N-O 2.78Å; A258-R281 PolarHBondContact O-N 2.79Å; R281-L313 PolarHBondContact NH1-O 2.98Å; R281-G314 PolarHBondContact NH1-O 2.78Å; R281-E322 WeakPolarHBondContact CD-OE2 3.36Å; R281-E322 HydrophobicContact CG-CG 3.71Å; R281-E322 IonicContact CZ-OE1 2.57Å; R281-E322 IonicContact CZ-OE2 3.83Å; R281-E322 VanDerWaalsContact NE-CD 3.3Å; R281-E322 IonicContact NE-OE1 3.96Å; R281-E322 PolarHBondContact NE-OE1 2.85Å; R281-E322 IonicContact NE-OE2 2.92Å; R281-E322 PolarHBondContact NE-OE2 2.74Å; R281-E322 VanDerWaalsContact NE-OE2 3.1Å; R281-E322 IonicContact NH1-OE2 3.27Å; R281-E322 PolarHBondContact NH1-OE2 2.79Å; R281-E322 IonicContact NH2-OE1 2.85Å; R281-E322 PolarHBondContact NH2-OE1 2.9Å; R281-E322 IonicContact NH2-OE2 2.78Å; R281-E322 PolarHBondContact NH2-OE2 3.5Å; R281-F323 WeakPolarHBondContact CA-O 3.36Å; R281-F323 WeakPolarHBondContact CG-O 2.94Å; R281-W324 HydrophobicContact CB-CD2 3.71Å; R281-W324 HydrophobicContact CB-CE3 3.7Å; R281-W324 HydrophobicContact CB-CG 4.34Å; R281-W324 HydrophobicContact CB-CH2 3.87Å; R281-W324 HydrophobicContact CB-CZ2 3.87Å; R281-W324 HydrophobicContact CB-CZ3 3.79Å; R281-W324 VanDerWaalsContact CD-CE2 3.44Å; R281-W324 HydrophobicContact CG-CD2 3.95Å; R281-W324 HydrophobicContact CG-CE3 4.45Å; R281-W324 HydrophobicContact CG-CG 4.15Å; R281-W324 HydrophobicContact CG-CZ2 4.24Å
282L94Very high81Confident0 Ų061.1 Ų61.10%029%0.287CS..EExtended strand (participates in β ladder)trans-120.5153.8-177.1-62.2174.7000109.8C230 S255 V256 I280 E322 F323 M325 F334C230-L282 VanDerWaalsContact SG-CD2 3.57Å; S255-L282 CarbonylContact O-C 3.45Å; S255-L282 VanDerWaalsContact O-CA 3.23Å; S255-L282 WeakPolarHBondContact O-CA 3.39Å; V256-L282 HydrophobicContact CB-CD2 4.32Å; V256-L282 HydrophobicContact CG2-CD2 3.66Å; I280-L282 HydrophobicContact CD1-CD2 4.35Å; I280-L282 HydrophobicContact CG1-CD2 4.31Å; L282-E322 CarbonylContact O-C 3.53Å; L282-E322 VanDerWaalsContact O-CA 3.26Å; L282-E322 WeakPolarHBondContact O-CA 3.31Å; L282-F323 HydrophobicContact CB-CD2 4.41Å; L282-F323 HydrophobicContact CB-CE1 4.24Å; L282-F323 HydrophobicContact CB-CE2 3.9Å; L282-F323 HydrophobicContact CB-CZ 3.8Å; L282-F323 HydrophobicContact CD1-CE2 3.73Å; L282-F323 HydrophobicContact CD1-CZ 3.94Å; L282-F323 HydrophobicContact CG-CE2 4.32Å; L282-F323 PolarHBondContact N-O 2.94Å; L282-F323 PolarHBondContact O-N 3.48Å; L282-M325 HydrophobicContact CD1-SD 4.08Å; L282-F334 HydrophobicContact CD1-CE1 4.21Å; L282-F334 HydrophobicContact CD1-CE2 3.63Å; L282-F334 HydrophobicContact CD1-CZ 3.37Å
283R90.9Very high83.3Confident0 Ų051.2 Ų51.20%025%0.248CC..EExtended strand (participates in β ladder)trans-124130168.5-175-177.1-178-92.4-10.9110.7S70 L73 S88 S255 T257 P285 G321S70-R283 PolarHBondContact O-NE 2.86Å; S70-R283 PolarHBondContact O-NH1 2.77Å; S70-R283 PolarHBondContact O-NH2 2.83Å; L73-R283 PolarHBondContact O-NH1 3.24Å; L73-R283 PolarHBondContact O-NH2 3.43Å; S88-R283 PolarHBondContact OG-NH1 3.35Å; S255-R283 PolarHBondContact N-O 3.06Å; S255-R283 PolarHBondContact O-N 2.94Å; T257-R283 HydrophobicContact CG2-CB 3.75Å; R283-P285 WeakPolarHBondContact O-CD 3.48Å; R283-G321 CarbonylContact C-O 3.2Å; R283-G321 WeakPolarHBondContact CA-O 3.35Å
284N89.3Confident85.4Confident0 Ų043.9 Ų43.90%022%0.222CC..  trans-80120.5168.3-170.3-24.4000110.1H252 Y254 W286 G287 K288 R289 G321H252-N284 PolarHBondContact NE2-OD1 2.92Å; Y254-N284 HydrophobicContact CD1-CB 4.16Å; Y254-N284 HydrophobicContact CE1-CB 3.74Å; N284-W286 PolarHBondContact O-N 2.9Å; N284-W286 WeakPolarHBondContact OD1-CB 3.3Å; N284-W286 PolarHBondContact OD1-N 3.37Å; N284-G287 PolarHBondContact O-N 3.19Å; N284-K288 VanDerWaalsContact CG-O 3.28Å; N284-K288 PolarHBondContact ND2-O 2.62Å; N284-R289 PolarHBondContact ND2-O 2.76Å; N284-G321 PolarHBondContact N-O 3.14Å
285P82.3Confident87.1Confident0 Ų041.3 Ų41.30%020%0.196CC..THydrogen-bonded Turntrans-56.7-16.3175.7-27.333.8000116.4Q75 V84 A85 H252 A253 R283 G287Q75-P285 PolarHBondContact N-O 2.93Å; V84-P285 HydrophobicContact CB-CB 3.9Å; V84-P285 HydrophobicContact CG1-CB 3.73Å; A85-P285 HydrophobicContact CB-CG 3.71Å; H252-P285 WeakPolarHBondContact NE2-CD 3.49Å; A253-P285 WeakPolarHBondContact O-CD 3.38Å; A253-P285 WeakPolarHBondContact O-CG 3.17Å; R283-P285 WeakPolarHBondContact O-CD 3.48Å; P285-G287 PolarHBondContact O-N 2.88Å
286W81.4Confident88.3Confident43 Ų4335.2 Ų35.216%0.16317%0.17CC..THydrogen-bonded Turntrans-75.3-10.4174.3-66.2-9.3000113.6H74 E241 V249 H252 N284 K288H74-W286 PolarHBondContact CD2-O 3.33Å; E241-W286 HydrophobicContact CB-CH2 4.3Å; E241-W286 HydrophobicContact CB-CZ2 4.32Å; E241-W286 HydrophobicContact CG-CZ2 4.41Å; E241-W286 WeakPolarHBondContact OE2-CZ2 3.39Å; V249-W286 HydrophobicContact CG1-CH2 3.69Å; V249-W286 HydrophobicContact CG1-CZ2 4.33Å; V249-W286 HydrophobicContact CG1-CZ3 4.15Å; V249-W286 HydrophobicContact CG2-CE3 4.28Å; V249-W286 HydrophobicContact CG2-CH2 4.09Å; V249-W286 HydrophobicContact CG2-CZ3 3.66Å; H252-W286 AromaticContact CE1-CD1 3.7Å; H252-W286 AromaticContact CE1-CE2 3.73Å; H252-W286 AromaticContact CE1-NE1 3.33Å; H252-W286 PolarHBondContact CE1-NE1 2.62Å; H252-W286 VanDerWaalsContact CE1-NE1 3.33Å; H252-W286 AromaticContact NE2-CD1 4Å; H252-W286 AromaticContact NE2-NE1 3.91Å; N284-W286 PolarHBondContact O-N 2.9Å; N284-W286 WeakPolarHBondContact OD1-CB 3.3Å; N284-W286 PolarHBondContact OD1-N 3.37Å; W286-K288 HydrophobicContact CB-CG 3.99Å; W286-K288 PolarHBondContact O-N 2.85Å
287G78.9Confident88.7Confident10 Ų1029.7 Ų29.710%0.10315%0.147CC..SBendtrans6523-174.700000113.5N284 P285 D320N284-G287 PolarHBondContact O-N 3.19Å; P285-G287 PolarHBondContact O-N 2.88Å; G287-D320 CarbonylContact C-O 3.53Å; G287-D320 VanDerWaalsContact CA-O 3.3Å; G287-D320 WeakPolarHBondContact CA-O 3.49Å; G287-D320 CarbonylContact O-C 3.55Å
288K80.1Confident88.5Confident107 Ų10734.4 Ų34.447%0.46517%0.172SC..  trans-165172.3-179.362.2-173.1174.2-1700110N284 W286 N319N284-K288 VanDerWaalsContact CG-O 3.28Å; N284-K288 PolarHBondContact ND2-O 2.62Å; W286-K288 HydrophobicContact CB-CG 3.99Å; W286-K288 PolarHBondContact O-N 2.85Å; K288-N319 WeakPolarHBondContact CA-OD1 3.46Å
289R83.2Confident88.3Confident100 Ų10032.6 Ų32.638%0.37717%0.165SC..  trans64.195.2179.5-61.9-176.9-173-170.810.3111.6E243 N284 N319E243-R289 VanDerWaalsContact OE2-CD 3.26Å; E243-R289 WeakPolarHBondContact OE2-CD 3.26Å; E243-R289 IonicContact OE2-CZ 2.67Å; E243-R289 IonicContact OE2-NE 3.48Å; E243-R289 PolarHBondContact OE2-NE 2.86Å; E243-R289 IonicContact OE2-NH1 2.81Å; E243-R289 PolarHBondContact OE2-NH1 3.27Å; N284-R289 PolarHBondContact ND2-O 2.76Å; R289-N319 PolarHBondContact N-OD1 3.28Å
290E89.6Confident88Confident22 Ų2238.1 Ų38.110%0.10319%0.191CC..  trans-114.2169.7-171-67.8165.1-167.300111.2G247 N292 N319 D320 G321 F323G247-E290 WeakPolarHBondContact CA-O 3.48Å; E290-N292 PolarHBondContact O-N 2.92Å; E290-N319 WeakPolarHBondContact OE1-CA 3.3Å; E290-D320 PolarHBondContact OE1-N 3.26Å; E290-G321 WeakPolarHBondContact OE1-CA 3.24Å; E290-G321 PolarHBondContact OE1-N 3.22Å; E290-F323 HydrophobicContact CB-CB 4.12Å; E290-F323 HydrophobicContact CB-CD1 3.87Å; E290-F323 HydrophobicContact CB-CG 4.23Å; E290-F323 HydrophobicContact CG-CB 4.34Å; E290-F323 HydrophobicContact CG-CD1 3.9Å
291W91.9Very high87.5Confident9 Ų940.9 Ų40.93%0.03420%0.204CC..  trans-62.1128.5173.2171.7-114.4000111.7M246 L248 G293 A294 S296 F323 M325 D329M246-W291 HydrophobicContact CB-CE3 3.89Å; M246-W291 HydrophobicContact CB-CH2 4.3Å; M246-W291 HydrophobicContact CB-CZ3 3.49Å; M246-W291 VanDerWaalsContact CB-CZ3 3.49Å; M246-W291 HydrophobicContact CE-CE3 4.48Å; M246-W291 HydrophobicContact CE-CH2 3.4Å; M246-W291 VanDerWaalsContact CE-CH2 3.4Å; M246-W291 HydrophobicContact CE-CZ2 3.83Å; M246-W291 HydrophobicContact CE-CZ3 3.79Å; M246-W291 HydrophobicContact CG-CH2 4.41Å; M246-W291 HydrophobicContact CG-CZ3 4.02Å; L248-W291 HydrophobicContact CD1-CE3 3.85Å; L248-W291 HydrophobicContact CD1-CZ3 3.87Å; L248-W291 HydrophobicContact CD2-CB 4.47Å; L248-W291 HydrophobicContact CD2-CE3 4.22Å; L248-W291 HydrophobicContact CG-CE3 3.89Å; L248-W291 HydrophobicContact CG-CZ3 4.32Å; W291-G293 VanDerWaalsContact NE1-C 3.27Å; W291-A294 PolarHBondContact NE1-O 3.38Å; W291-S296 WeakPolarHBondContact O-CB 3.29Å; W291-F323 HydrophobicContact CB-CB 4.38Å; W291-F323 HydrophobicContact CB-CD2 3.24Å; W291-F323 HydrophobicContact CB-CE2 3.52Å; W291-F323 HydrophobicContact CB-CG 3.85Å; W291-F323 HydrophobicContact CB-CZ 4.32Å; W291-F323 HydrophobicContact CG-CD2 4.24Å; W291-F323 HydrophobicContact CG-CE2 4.49Å; W291-M325 HydrophobicContact CB-CE 4.43Å; W291-M325 HydrophobicContact CD2-CE 3.32Å; W291-M325 HydrophobicContact CE3-CE 3.44Å; W291-M325 VanDerWaalsContact CE3-CE 3.44Å; W291-M325 HydrophobicContact CG-CE 3.81Å; W291-M325 HydrophobicContact CH2-CE 3.98Å; W291-M325 HydrophobicContact CZ2-CE 3.88Å; W291-M325 HydrophobicContact CZ3-CE 3.76Å; W291-D329 HydrophobicContact CZ2-CB 4.27Å
292N90.4Very high87.2Confident111 Ų11139.3 Ų39.359%0.59420%0.198SC*.  trans-101.73.4179.2-67.1-33.2000114M246 E290M246-N292 PolarHBondContact O-N 3.48Å; E290-N292 PolarHBondContact O-N 2.92Å
293G90.6Very high86.7Confident14 Ų1445.8 Ų45.814%0.14423%0.226CC..SBendtrans-87.8-158.7-178.900000114W291 W295 S296W291-G293 VanDerWaalsContact NE1-C 3.27Å; G293-W295 PolarHBondContact O-N 3.38Å; G293-S296 WeakPolarHBondContact O-CB 3.27Å; G293-S296 PolarHBondContact O-N 3.35Å; G293-S296 PolarHBondContact O-OG 3.04Å
294A89.3Confident86.3Confident34 Ų3452.1 Ų52.128%0.28125%0.254SS..THydrogen-bonded Turntrans-58137.4177.300000111.3W291 S296 E301W291-A294 PolarHBondContact NE1-O 3.38Å; A294-S296 PolarHBondContact O-N 2.93Å; A294-E301 WeakPolarHBondContact CB-OE1 3.22Å
295W90.5Very high86Confident19 Ų1952.2 Ų52.27%0.07226%0.255CS..THydrogen-bonded Turntrans66.911.5-176.3-51.991.5000116.3L264 L277 M279 G293 S299 E301 W302 V305 W324 T326L264-W295 HydrophobicContact CD2-CH2 3.74Å; L264-W295 HydrophobicContact CD2-CZ2 4.24Å; L277-W295 HydrophobicContact CD2-CD2 4.25Å; L277-W295 HydrophobicContact CD2-CH2 3.85Å; L277-W295 HydrophobicContact CD2-CZ2 3.33Å; L277-W295 HydrophobicContact CD2-CZ3 4.48Å; M279-W295 HydrophobicContact CE-CB 3.8Å; M279-W295 HydrophobicContact CE-CD2 4.08Å; M279-W295 HydrophobicContact CE-CE3 4.26Å; M279-W295 HydrophobicContact CE-CG 3.89Å; M279-W295 HydrophobicContact SD-CD2 4.49Å; M279-W295 HydrophobicContact SD-CG 4.43Å; G293-W295 PolarHBondContact O-N 3.38Å; W295-S299 WeakPolarHBondContact CA-OG 3.41Å; W295-S299 PolarHBondContact N-OG 3.11Å; W295-E301 HydrophobicContact CD2-CB 3.85Å; W295-E301 HydrophobicContact CE3-CB 4Å; W295-E301 HydrophobicContact CG-CB 4.45Å; W295-E301 HydrophobicContact CH2-CB 4.03Å; W295-E301 WeakPolarHBondContact CH2-O 3.45Å; W295-E301 HydrophobicContact CZ2-CB 3.88Å; W295-E301 HydrophobicContact CZ3-CB 4.08Å; W295-E301 WeakPolarHBondContact CZ3-O 3.46Å; W295-W302 HydrophobicContact CB-CZ2 4.26Å; W295-W302 AromaticContact CE3-CD2 3.75Å; W295-W302 HydrophobicContact CE3-CD2 3.75Å; W295-W302 AromaticContact CE3-CE2 3.85Å; W295-W302 AromaticContact CE3-CE3 3.81Å; W295-W302 HydrophobicContact CE3-CE3 3.81Å; W295-W302 HydrophobicContact CE3-CG 4.34Å; W295-W302 HydrophobicContact CE3-CH2 4.08Å; W295-W302 HydrophobicContact CE3-CZ2 4Å; W295-W302 AromaticContact CE3-CZ3 3.98Å; W295-W302 HydrophobicContact CE3-CZ3 3.98Å; W295-W302 HydrophobicContact CZ3-CD2 4.08Å; W295-W302 AromaticContact CZ3-CE3 3.8Å; W295-W302 HydrophobicContact CZ3-CE3 3.8Å; W295-W302 HydrophobicContact CZ3-CZ3 4.11Å; W295-W302 PolarHBondContact O-NE1 2.84Å; W295-W302 VanDerWaalsContact O-NE1 3.11Å; W295-V305 HydrophobicContact CH2-CG2 3.88Å; W295-V305 HydrophobicContact CZ3-CG2 3.63Å; W295-W324 CarbonylContact C-O 3.55Å; W295-W324 VanDerWaalsContact O-O 3.1Å; W295-T326 HydrophobicContact CG-CG2 4.35Å
296S89Confident86Confident16 Ų1654.9 Ų54.911%0.11227%0.273CS..  trans-54.1165.4161.6570000112W291 G293 A294 N298 S299 W302W291-S296 WeakPolarHBondContact O-CB 3.29Å; G293-S296 WeakPolarHBondContact O-CB 3.27Å; G293-S296 PolarHBondContact O-N 3.35Å; G293-S296 PolarHBondContact O-OG 3.04Å; A294-S296 PolarHBondContact O-N 2.93Å; S296-N298 PolarHBondContact O-N 3.41Å; S296-N298 VanDerWaalsContact O-N 3.15Å; S296-S299 WeakPolarHBondContact O-CB 3.23Å; S296-S299 PolarHBondContact O-N 3.25Å; S296-S299 WeakPolarHBondContact OG-CB 3.43Å; S296-W302 VanDerWaalsContact O-CD1 3.29Å; S296-W302 PolarHBondContact O-NE1 3.39Å
297D84.1Confident86.1Confident12 Ų1258.2 Ų58.26%0.06429%0.294CS..THydrogen-bonded Turntrans-56.9-36.9-172.9-77.120.7000113.7V317D297-V317 HydrophobicContact CB-CG1 4.44Å
298N84.9Confident86.3Confident136 Ų13661.9 Ų61.973%0.72732%0.318SS*.THydrogen-bonded Turntrans-94.58.7178.1-65.6-52.2000113.9S296 V317S296-N298 PolarHBondContact O-N 3.41Å; S296-N298 VanDerWaalsContact O-N 3.15Å; N298-V317 WeakPolarHBondContact OD1-CG1 3.34Å
299S88.3Confident86.3Confident12 Ų1257.6 Ų57.68%0.08430%0.3CS..  trans-68.2133.6-174.9166.30000112.8W295 S296 E301 W302W295-S299 WeakPolarHBondContact CA-OG 3.41Å; W295-S299 PolarHBondContact N-OG 3.11Å; S296-S299 WeakPolarHBondContact O-CB 3.23Å; S296-S299 PolarHBondContact O-N 3.25Å; S296-S299 WeakPolarHBondContact OG-CB 3.43Å; S299-E301 PolarHBondContact O-N 3.31Å; S299-E301 WeakPolarHBondContact OG-CB 3.33Å; S299-E301 PolarHBondContact OG-N 3.46Å; S299-E301 PolarHBondContact OG-OE2 2.77Å; S299-W302 PolarHBondContact O-N 3.41Å
300E87.7Confident86.3Confident117 Ų11755.6 Ų55.655%0.54729%0.292SS..G310 helixtrans-63.5-24.5177.2-73.1-72.7130.400112.6W302 K303E300-W302 PolarHBondContact O-N 2.74Å; E300-K303 VanDerWaalsContact CD-CE 3.47Å; E300-K303 WeakPolarHBondContact O-CB 3.33Å; E300-K303 WeakPolarHBondContact O-CG 3.39Å; E300-K303 PolarHBondContact O-N 3.08Å; E300-K303 VanDerWaalsContact OE1-CE 3.26Å; E300-K303 WeakPolarHBondContact OE1-CE 3.43Å; E300-K303 IonicContact OE1-NZ 2.74Å; E300-K303 PolarHBondContact OE1-NZ 2.6Å; E300-K303 VanDerWaalsContact OE2-CD 3.26Å; E300-K303 WeakPolarHBondContact OE2-CD 3.32Å; E300-K303 WeakPolarHBondContact OE2-CE 3.32Å; E300-K303 IonicContact OE2-NZ 2.65Å; E300-K303 PolarHBondContact OE2-NZ 2.82Å
301E86.9Confident86Confident58 Ų5863 Ų6327%0.27132%0.324SS..G310 helixtrans-58.5-30.2178-68.987.2142.200112.4A294 W295 S299 K303 K304A294-E301 WeakPolarHBondContact CB-OE1 3.22Å; W295-E301 HydrophobicContact CD2-CB 3.85Å; W295-E301 HydrophobicContact CE3-CB 4Å; W295-E301 HydrophobicContact CG-CB 4.45Å; W295-E301 HydrophobicContact CH2-CB 4.03Å; W295-E301 WeakPolarHBondContact CH2-O 3.45Å; W295-E301 HydrophobicContact CZ2-CB 3.88Å; W295-E301 HydrophobicContact CZ3-CB 4.08Å; W295-E301 WeakPolarHBondContact CZ3-O 3.46Å; S299-E301 PolarHBondContact O-N 3.31Å; S299-E301 WeakPolarHBondContact OG-CB 3.33Å; S299-E301 PolarHBondContact OG-N 3.46Å; S299-E301 PolarHBondContact OG-OE2 2.77Å; E301-K303 PolarHBondContact O-N 2.99Å; E301-K303 VanDerWaalsContact O-N 3.13Å; E301-K304 VanDerWaalsContact O-CB 3.3Å; E301-K304 WeakPolarHBondContact O-CB 3.5Å; E301-K304 WeakPolarHBondContact O-CG 3.26Å; E301-K304 PolarHBondContact O-N 2.65Å
302W87.1Confident85.6Confident6 Ų670.5 Ų70.52%0.02335%0.352CS..G310 helixtrans-56.8-29.3172.9-72.4115000112.1M279 W295 S296 S299 E300 K304 V305 R310 L313 L315 W324M279-W302 HydrophobicContact CE-CH2 3.95Å; M279-W302 HydrophobicContact CE-CZ2 4.23Å; W295-W302 HydrophobicContact CB-CZ2 4.26Å; W295-W302 AromaticContact CE3-CD2 3.75Å; W295-W302 HydrophobicContact CE3-CD2 3.75Å; W295-W302 AromaticContact CE3-CE2 3.85Å; W295-W302 AromaticContact CE3-CE3 3.81Å; W295-W302 HydrophobicContact CE3-CE3 3.81Å; W295-W302 HydrophobicContact CE3-CG 4.34Å; W295-W302 HydrophobicContact CE3-CH2 4.08Å; W295-W302 HydrophobicContact CE3-CZ2 4Å; W295-W302 AromaticContact CE3-CZ3 3.98Å; W295-W302 HydrophobicContact CE3-CZ3 3.98Å; W295-W302 HydrophobicContact CZ3-CD2 4.08Å; W295-W302 AromaticContact CZ3-CE3 3.8Å; W295-W302 HydrophobicContact CZ3-CE3 3.8Å; W295-W302 HydrophobicContact CZ3-CZ3 4.11Å; W295-W302 PolarHBondContact O-NE1 2.84Å; W295-W302 VanDerWaalsContact O-NE1 3.11Å; S296-W302 VanDerWaalsContact O-CD1 3.29Å; S296-W302 PolarHBondContact O-NE1 3.39Å; S299-W302 PolarHBondContact O-N 3.41Å; E300-W302 PolarHBondContact O-N 2.74Å; W302-K304 PolarHBondContact O-N 3.19Å; W302-V305 HydrophobicContact CE3-CB 4.37Å; W302-V305 HydrophobicContact CE3-CG2 4.25Å; W302-V305 HydrophobicContact CZ3-CG2 4.5Å; W302-V305 WeakPolarHBondContact O-CB 3.39Å; W302-V305 PolarHBondContact O-N 3.17Å; W302-R310 VanDerWaalsContact C-CZ 3.45Å; W302-R310 HydrophobicContact CE3-CG 4.22Å; W302-R310 PolarHBondContact O-NE 3.07Å; W302-R310 PolarHBondContact O-NH2 2.76Å; W302-L313 HydrophobicContact CH2-CD1 4.22Å; W302-L313 HydrophobicContact CZ3-CD1 3.79Å; W302-L315 HydrophobicContact CB-CD2 4.48Å; W302-L315 HydrophobicContact CD2-CD1 4.33Å; W302-L315 HydrophobicContact CD2-CD2 3.67Å; W302-L315 HydrophobicContact CE3-CD2 3.99Å; W302-L315 HydrophobicContact CG-CD2 3.88Å; W302-L315 HydrophobicContact CH2-CD1 4.33Å; W302-L315 HydrophobicContact CZ2-CD1 3.78Å; W302-W324 HydrophobicContact CH2-CB 4.09Å; W302-W324 HydrophobicContact CH2-CD2 4.4Å; W302-W324 AromaticContact CH2-CG 3.95Å; W302-W324 HydrophobicContact CH2-CG 3.95Å; W302-W324 HydrophobicContact CZ2-CB 3.62Å; W302-W324 AromaticContact CZ2-CD1 3.98Å; W302-W324 AromaticContact CZ2-CG 3.84Å; W302-W324 HydrophobicContact CZ2-CG 3.84Å
303K85Confident85.2Confident135 Ų13565.7 Ų65.759%0.58733%0.327SS*.G310 helixtrans-55.4-23.7175.4-63.5-176.7-176.6171.30113.3E300 E301 V305 R310E300-K303 VanDerWaalsContact CD-CE 3.47Å; E300-K303 WeakPolarHBondContact O-CB 3.33Å; E300-K303 WeakPolarHBondContact O-CG 3.39Å; E300-K303 PolarHBondContact O-N 3.08Å; E300-K303 VanDerWaalsContact OE1-CE 3.26Å; E300-K303 WeakPolarHBondContact OE1-CE 3.43Å; E300-K303 IonicContact OE1-NZ 2.74Å; E300-K303 PolarHBondContact OE1-NZ 2.6Å; E300-K303 VanDerWaalsContact OE2-CD 3.26Å; E300-K303 WeakPolarHBondContact OE2-CD 3.32Å; E300-K303 WeakPolarHBondContact OE2-CE 3.32Å; E300-K303 IonicContact OE2-NZ 2.65Å; E300-K303 PolarHBondContact OE2-NZ 2.82Å; E301-K303 PolarHBondContact O-N 2.99Å; E301-K303 VanDerWaalsContact O-N 3.13Å; K303-V305 VanDerWaalsContact C-N 3.33Å; K303-R310 VanDerWaalsContact CA-NH2 3.25Å
304K82.7Confident84.6Confident133 Ų13366.6 Ų66.658%0.57834%0.336SS*.G310 helixtrans-78.1-14.7177-57172.4-176.1170.10113.7L264 G265 E301 W302L264-K304 HydrophobicContact CD2-CB 4.43Å; G265-K304 PolarHBondContact N-O 2.8Å; E301-K304 VanDerWaalsContact O-CB 3.3Å; E301-K304 WeakPolarHBondContact O-CB 3.5Å; E301-K304 WeakPolarHBondContact O-CG 3.26Å; E301-K304 PolarHBondContact O-N 2.65Å; W302-K304 PolarHBondContact O-N 3.19Å
305V81.9Confident84.1Confident3 Ų366.8 Ų66.82%0.01833%0.332CS..SBendtrans-101.5137.2-179.9-179.50000109.3V262 L264 W295 W302 K303 E309 R310V262-V305 HydrophobicContact CG1-CG1 4.35Å; V262-V305 HydrophobicContact CG1-CG2 4.24Å; L264-V305 HydrophobicContact CD2-CG2 4.01Å; W295-V305 HydrophobicContact CH2-CG2 3.88Å; W295-V305 HydrophobicContact CZ3-CG2 3.63Å; W302-V305 HydrophobicContact CE3-CB 4.37Å; W302-V305 HydrophobicContact CE3-CG2 4.25Å; W302-V305 HydrophobicContact CZ3-CG2 4.5Å; W302-V305 WeakPolarHBondContact O-CB 3.39Å; W302-V305 PolarHBondContact O-N 3.17Å; K303-V305 VanDerWaalsContact C-N 3.33Å; V305-E309 HydrophobicContact CG1-CB 3.57Å; V305-E309 HydrophobicContact CG1-CG 3.49Å; V305-E309 VanDerWaalsContact CG1-CG 3.49Å; V305-R310 HydrophobicContact CB-CG 4.15Å; V305-R310 HydrophobicContact CG1-CG 3.84Å; V305-R310 PolarHBondContact O-NE 3.21Å; V305-R310 PolarHBondContact O-NH2 2.8Å
306S82.8Confident83.2Confident55 Ų5568.5 Ų68.539%0.38535%0.345SS..  trans-65.4152.7179.969.20000112S308 E309 R310S306-S308 PolarHBondContact O-N 2.77Å; S306-S308 PolarHBondContact OG-OG 3.33Å; S306-E309 PolarHBondContact O-N 3.26Å; S306-E309 VanDerWaalsContact O-N 3.11Å; S306-E309 VanDerWaalsContact OG-CB 3.26Å; S306-E309 WeakPolarHBondContact OG-CB 3.4Å; S306-E309 PolarHBondContact OG-N 2.78Å; S306-R310 WeakPolarHBondContact O-CG 3.31Å; S306-R310 PolarHBondContact O-N 3Å
307N82.9Confident82.5Confident114 Ų11471.8 Ų71.861%0.6136%0.364SS*.Hα-helixtrans-59.8-34.8179.1-70.7-14.1000112.8K311N307-K311 WeakPolarHBondContact O-CG 3.49Å; N307-K311 PolarHBondContact O-N 3.17Å
308S83.1Confident82.1Confident87 Ų8777.4 Ų77.461%0.60839%0.39SS*.Hα-helixtrans-65.6-40.917652.60000111.9S306 R312S306-S308 PolarHBondContact O-N 2.77Å; S306-S308 PolarHBondContact OG-OG 3.33Å; S308-R312 WeakPolarHBondContact O-CB 3.3Å; S308-R312 PolarHBondContact O-N 2.95Å
309E80.9Confident81.6Confident16 Ų1676.5 Ų76.58%0.07539%0.385CS..Hα-helixtrans-68.3-41.4177.5-172.572-17700111.3V262 V305 S306 K311 R312 L313V262-E309 HydrophobicContact CG1-CG 4.1Å; V305-E309 HydrophobicContact CG1-CB 3.57Å; V305-E309 HydrophobicContact CG1-CG 3.49Å; V305-E309 VanDerWaalsContact CG1-CG 3.49Å; S306-E309 PolarHBondContact O-N 3.26Å; S306-E309 VanDerWaalsContact O-N 3.11Å; S306-E309 VanDerWaalsContact OG-CB 3.26Å; S306-E309 WeakPolarHBondContact OG-CB 3.4Å; S306-E309 PolarHBondContact OG-N 2.78Å; E309-K311 PolarHBondContact O-N 3.23Å; E309-R312 WeakPolarHBondContact O-CB 3.27Å; E309-R312 PolarHBondContact O-N 3.39Å; E309-R312 IonicContact OE1-CZ 2.76Å; E309-R312 VanDerWaalsContact OE1-CZ 3.27Å; E309-R312 IonicContact OE1-NE 2.78Å; E309-R312 IonicContact OE1-NH1 3Å; E309-R312 IonicContact OE1-NH2 3.62Å; E309-R312 PolarHBondContact OE1-NH2 3.21Å; E309-R312 IonicContact OE2-CZ 2.62Å; E309-R312 IonicContact OE2-NE 2.98Å; E309-R312 PolarHBondContact OE2-NE 2.91Å; E309-R312 IonicContact OE2-NH1 3.35Å; E309-R312 PolarHBondContact OE2-NH1 3.02Å; E309-R312 IonicContact OE2-NH2 3.33Å; E309-R312 PolarHBondContact OE2-NH2 2.98Å; E309-L313 HydrophobicContact CG-CD1 4.47Å; E309-L313 VanDerWaalsContact O-CG 3.31Å; E309-L313 WeakPolarHBondContact O-CG 3.47Å; E309-L313 PolarHBondContact O-N 3.35Å
310R83.6Confident81.1Confident59 Ų5976.8 Ų76.822%0.22339%0.386CS..Hα-helixtrans-61.4-44.3174.6-65-173.3-145.5166.414.1112.6W302 K303 V305 S306 R312 L313 G314 L315W302-R310 VanDerWaalsContact C-CZ 3.45Å; W302-R310 HydrophobicContact CE3-CG 4.22Å; W302-R310 PolarHBondContact O-NE 3.07Å; W302-R310 PolarHBondContact O-NH2 2.76Å; K303-R310 VanDerWaalsContact CA-NH2 3.25Å; V305-R310 HydrophobicContact CB-CG 4.15Å; V305-R310 HydrophobicContact CG1-CG 3.84Å; V305-R310 PolarHBondContact O-NE 3.21Å; V305-R310 PolarHBondContact O-NH2 2.8Å; S306-R310 WeakPolarHBondContact O-CG 3.31Å; S306-R310 PolarHBondContact O-N 3Å; R310-R312 VanDerWaalsContact C-N 3.3Å; R310-R312 PolarHBondContact O-N 3.34Å; R310-L313 PolarHBondContact O-N 3.42Å; R310-G314 PolarHBondContact O-N 3.47Å; R310-L315 HydrophobicContact CB-CB 4.5Å; R310-L315 HydrophobicContact CB-CD2 4.35Å; R310-L315 HydrophobicContact CG-CD2 4.3Å; R310-L315 PolarHBondContact O-N 2.87Å
311K83.2Confident80.9Confident177 Ų17771.2 Ų71.277%0.7736%0.36SS*.Hα-helixtrans-61-40.2173.7-74.9-176.2179-1720111.7N307 E309 L313 G314N307-K311 WeakPolarHBondContact O-CG 3.49Å; N307-K311 PolarHBondContact O-N 3.17Å; E309-K311 PolarHBondContact O-N 3.23Å; K311-L313 VanDerWaalsContact C-N 3.29Å; K311-L313 PolarHBondContact O-N 3.03Å; K311-G314 PolarHBondContact O-N 3.3Å
312R83.4Confident81Confident166 Ų16669.1 Ų69.163%0.62635%0.35SS*.Hα-helixtrans-64.9-33.1176.2-170.2-179.479.2-167.313.2112.8S308 E309 R310 G314S308-R312 WeakPolarHBondContact O-CB 3.3Å; S308-R312 PolarHBondContact O-N 2.95Å; E309-R312 WeakPolarHBondContact O-CB 3.27Å; E309-R312 PolarHBondContact O-N 3.39Å; E309-R312 IonicContact OE1-CZ 2.76Å; E309-R312 VanDerWaalsContact OE1-CZ 3.27Å; E309-R312 IonicContact OE1-NE 2.78Å; E309-R312 IonicContact OE1-NH1 3Å; E309-R312 IonicContact OE1-NH2 3.62Å; E309-R312 PolarHBondContact OE1-NH2 3.21Å; E309-R312 IonicContact OE2-CZ 2.62Å; E309-R312 IonicContact OE2-NE 2.98Å; E309-R312 PolarHBondContact OE2-NE 2.91Å; E309-R312 IonicContact OE2-NH1 3.35Å; E309-R312 PolarHBondContact OE2-NH1 3.02Å; E309-R312 IonicContact OE2-NH2 3.33Å; E309-R312 PolarHBondContact OE2-NH2 2.98Å; R310-R312 VanDerWaalsContact C-N 3.3Å; R310-R312 PolarHBondContact O-N 3.34Å; R312-G314 PolarHBondContact O-N 3.39Å
313L82Confident81.3Confident10 Ų1068.9 Ų68.95%0.05235%0.349CS..Hα-helixtrans-75.1-11.2174.5-66.9171.2000112.6R260 V262 R281 W302 E309 R310 K311 L315 W324R260-L313 HydrophobicContact CB-CD2 3.92Å; R260-L313 HydrophobicContact CG-CD2 3.85Å; V262-L313 HydrophobicContact CG1-CD1 4.23Å; V262-L313 HydrophobicContact CG2-CD1 3.79Å; V262-L313 HydrophobicContact CG2-CD2 3.89Å; V262-L313 HydrophobicContact CG2-CG 4.46Å; R281-L313 PolarHBondContact NH1-O 2.98Å; W302-L313 HydrophobicContact CH2-CD1 4.22Å; W302-L313 HydrophobicContact CZ3-CD1 3.79Å; E309-L313 HydrophobicContact CG-CD1 4.47Å; E309-L313 VanDerWaalsContact O-CG 3.31Å; E309-L313 WeakPolarHBondContact O-CG 3.47Å; E309-L313 PolarHBondContact O-N 3.35Å; R310-L313 PolarHBondContact O-N 3.42Å; K311-L313 VanDerWaalsContact C-N 3.29Å; K311-L313 PolarHBondContact O-N 3.03Å; L313-L315 VanDerWaalsContact C-N 3.29Å; L313-W324 HydrophobicContact CB-CZ2 4.01Å; L313-W324 HydrophobicContact CD2-CH2 4.02Å; L313-W324 HydrophobicContact CD2-CZ2 4.12Å; L313-W324 WeakPolarHBondContact O-CZ2 3.25Å
314G78Confident81.7Confident34 Ų3462.6 Ų62.635%0.35132%0.322SS..THydrogen-bonded Turntrans61.541.1-174.800000111.4R281 R310 K311 R312 T316R281-G314 PolarHBondContact NH1-O 2.78Å; R310-G314 PolarHBondContact O-N 3.47Å; K311-G314 PolarHBondContact O-N 3.3Å; R312-G314 PolarHBondContact O-N 3.39Å; G314-T316 PolarHBondContact O-N 3.31Å
315L77.3Confident82.3Confident38 Ų3856.3 Ų56.320%0.19929%0.294CS..  trans-67.1109.2173.7-17769.8000108.8W302 R310 L313W302-L315 HydrophobicContact CB-CD2 4.48Å; W302-L315 HydrophobicContact CD2-CD1 4.33Å; W302-L315 HydrophobicContact CD2-CD2 3.67Å; W302-L315 HydrophobicContact CE3-CD2 3.99Å; W302-L315 HydrophobicContact CG-CD2 3.88Å; W302-L315 HydrophobicContact CH2-CD1 4.33Å; W302-L315 HydrophobicContact CZ2-CD1 3.78Å; R310-L315 HydrophobicContact CB-CB 4.5Å; R310-L315 HydrophobicContact CB-CD2 4.35Å; R310-L315 HydrophobicContact CG-CD2 4.3Å; R310-L315 PolarHBondContact O-N 2.87Å; L313-L315 VanDerWaalsContact C-N 3.29Å
316T72.1Confident82.9Confident54 Ų5456.7 Ų56.733%0.33130%0.297SS..  trans-91.1158163.343.30000108.7G314G314-T316 PolarHBondContact O-N 3.31Å
317V74.4Confident83.5Confident86 Ų8654.2 Ų54.252%0.52128%0.279SS..  trans-127.972.6173.9-176.30000105.9D297 N298D297-V317 HydrophobicContact CB-CG1 4.44Å; N298-V317 WeakPolarHBondContact OD1-CG1 3.34Å
318E75.7Confident84.1Confident130 Ų13053.4 Ų53.461%0.60727%0.272SS*.SBendtrans-142.6142.7-174.5-64-173.3-169.500107.8D320E318-D320 HydrophobicContact CB-CB 4.46Å; E318-D320 PolarHBondContact O-N 2.79Å
319N73.9Confident84.7Confident116 Ų11650.7 Ų50.762%0.6225%0.25SS*.SBendtrans-81.172175.9-174.57.2000109.2K288 R289 E290K288-N319 WeakPolarHBondContact CA-OD1 3.46Å; R289-N319 PolarHBondContact N-OD1 3.28Å; E290-N319 WeakPolarHBondContact OE1-CA 3.3Å
320D78.3Confident85.4Confident19 Ų1950 Ų5010%0.10225%0.247CC..SBendtrans-107.50.5-175.967.520.5000112.5H71 G287 E290 E318 E322H71-D320 IonicContact NE2-OD2 2.76Å; H71-D320 PolarHBondContact NE2-OD2 2.71Å; G287-D320 CarbonylContact C-O 3.53Å; G287-D320 VanDerWaalsContact CA-O 3.3Å; G287-D320 WeakPolarHBondContact CA-O 3.49Å; G287-D320 CarbonylContact O-C 3.55Å; E290-D320 PolarHBondContact OE1-N 3.26Å; E318-D320 HydrophobicContact CB-CB 4.46Å; E318-D320 PolarHBondContact O-N 2.79Å; D320-E322 VanDerWaalsContact C-N 3.34Å; D320-E322 WeakPolarHBondContact OD1-CA 3.28Å; D320-E322 VanDerWaalsContact OD1-CB 3.23Å; D320-E322 WeakPolarHBondContact OD1-CB 3.42Å; D320-E322 PolarHBondContact OD1-N 2.79Å
321G83.2Confident86Confident0 Ų047.3 Ų47.30%024%0.238CC..SBendtrans85.9-4.1-17800000114R283 N284 E290R283-G321 CarbonylContact C-O 3.2Å; R283-G321 WeakPolarHBondContact CA-O 3.35Å; N284-G321 PolarHBondContact N-O 3.14Å; E290-G321 WeakPolarHBondContact OE1-CA 3.24Å; E290-G321 PolarHBondContact OE1-N 3.22Å
322E89.9Confident86.5Confident14 Ų1442.6 Ų42.67%0.06522%0.217CC..EExtended strand (participates in β ladder)trans-94.1129.7176.6-170.2167.9-105.500111.2T257 R281 L282 D320T257-E322 VanDerWaalsContact CB-OE1 3.24Å; T257-E322 WeakPolarHBondContact CB-OE1 3.25Å; T257-E322 WeakPolarHBondContact CG2-OE1 3.39Å; T257-E322 PolarHBondContact OG1-OE1 2.76Å; R281-E322 WeakPolarHBondContact CD-OE2 3.36Å; R281-E322 HydrophobicContact CG-CG 3.71Å; R281-E322 IonicContact CZ-OE1 2.57Å; R281-E322 IonicContact CZ-OE2 3.83Å; R281-E322 VanDerWaalsContact NE-CD 3.3Å; R281-E322 IonicContact NE-OE1 3.96Å; R281-E322 PolarHBondContact NE-OE1 2.85Å; R281-E322 IonicContact NE-OE2 2.92Å; R281-E322 PolarHBondContact NE-OE2 2.74Å; R281-E322 VanDerWaalsContact NE-OE2 3.1Å; R281-E322 IonicContact NH1-OE2 3.27Å; R281-E322 PolarHBondContact NH1-OE2 2.79Å; R281-E322 IonicContact NH2-OE1 2.85Å; R281-E322 PolarHBondContact NH2-OE1 2.9Å; R281-E322 IonicContact NH2-OE2 2.78Å; R281-E322 PolarHBondContact NH2-OE2 3.5Å; L282-E322 CarbonylContact O-C 3.53Å; L282-E322 VanDerWaalsContact O-CA 3.26Å; L282-E322 WeakPolarHBondContact O-CA 3.31Å; D320-E322 VanDerWaalsContact C-N 3.34Å; D320-E322 WeakPolarHBondContact OD1-CA 3.28Å; D320-E322 VanDerWaalsContact OD1-CB 3.23Å; D320-E322 WeakPolarHBondContact OD1-CB 3.42Å; D320-E322 PolarHBondContact OD1-N 2.79Å
323F92.7Very high87Confident0 Ų037.2 Ų37.20%020%0.2CC..EExtended strand (participates in β ladder)trans-149.5154.6-177.858.6-90.2000112L248 Y254 R281 L282 E290 W291L248-F323 HydrophobicContact CD2-CE2 3.9Å; L248-F323 HydrophobicContact CD2-CZ 3.61Å; Y254-F323 HydrophobicContact CD1-CE1 4.2Å; Y254-F323 HydrophobicContact CD1-CZ 4.11Å; Y254-F323 AromaticContact CE1-CE1 3.95Å; Y254-F323 HydrophobicContact CE1-CE1 3.95Å; Y254-F323 AromaticContact CE1-CZ 3.95Å; Y254-F323 HydrophobicContact CE1-CZ 3.95Å; R281-F323 WeakPolarHBondContact CA-O 3.36Å; R281-F323 WeakPolarHBondContact CG-O 2.94Å; L282-F323 HydrophobicContact CB-CD2 4.41Å; L282-F323 HydrophobicContact CB-CE1 4.24Å; L282-F323 HydrophobicContact CB-CE2 3.9Å; L282-F323 HydrophobicContact CB-CZ 3.8Å; L282-F323 HydrophobicContact CD1-CE2 3.73Å; L282-F323 HydrophobicContact CD1-CZ 3.94Å; L282-F323 HydrophobicContact CG-CE2 4.32Å; L282-F323 PolarHBondContact N-O 2.94Å; L282-F323 PolarHBondContact O-N 3.48Å; E290-F323 HydrophobicContact CB-CB 4.12Å; E290-F323 HydrophobicContact CB-CD1 3.87Å; E290-F323 HydrophobicContact CB-CG 4.23Å; E290-F323 HydrophobicContact CG-CB 4.34Å; E290-F323 HydrophobicContact CG-CD1 3.9Å; W291-F323 HydrophobicContact CB-CB 4.38Å; W291-F323 HydrophobicContact CB-CD2 3.24Å; W291-F323 HydrophobicContact CB-CE2 3.52Å; W291-F323 HydrophobicContact CB-CG 3.85Å; W291-F323 HydrophobicContact CB-CZ 4.32Å; W291-F323 HydrophobicContact CG-CD2 4.24Å; W291-F323 HydrophobicContact CG-CE2 4.49Å
324W93.9Very high87.7Confident4 Ų437 Ų372%0.01520%0.199CC..EExtended strand (participates in β ladder)trans-99.2150174.4-76.396.8000111.6A258 R260 M279 R281 W295 W302 L313A258-W324 HydrophobicContact CB-CH2 3.64Å; A258-W324 HydrophobicContact CB-CZ2 4.14Å; A258-W324 HydrophobicContact CB-CZ3 4.39Å; R260-W324 HydrophobicContact CB-CH2 4.22Å; R260-W324 HydrophobicContact CB-CZ3 4.33Å; R260-W324 HydrophobicContact CG-CH2 3.79Å; R260-W324 HydrophobicContact CG-CZ3 4.35Å; M279-W324 HydrophobicContact CB-CE3 3.81Å; M279-W324 HydrophobicContact CB-CZ3 3.81Å; M279-W324 HydrophobicContact CE-CB 4.01Å; M279-W324 HydrophobicContact CE-CE3 4.26Å; R281-W324 HydrophobicContact CB-CD2 3.71Å; R281-W324 HydrophobicContact CB-CE3 3.7Å; R281-W324 HydrophobicContact CB-CG 4.34Å; R281-W324 HydrophobicContact CB-CH2 3.87Å; R281-W324 HydrophobicContact CB-CZ2 3.87Å; R281-W324 HydrophobicContact CB-CZ3 3.79Å; R281-W324 VanDerWaalsContact CD-CE2 3.44Å; R281-W324 HydrophobicContact CG-CD2 3.95Å; R281-W324 HydrophobicContact CG-CE3 4.45Å; R281-W324 HydrophobicContact CG-CG 4.15Å; R281-W324 HydrophobicContact CG-CZ2 4.24Å; W295-W324 CarbonylContact C-O 3.55Å; W295-W324 VanDerWaalsContact O-O 3.1Å; W302-W324 HydrophobicContact CH2-CB 4.09Å; W302-W324 HydrophobicContact CH2-CD2 4.4Å; W302-W324 AromaticContact CH2-CG 3.95Å; W302-W324 HydrophobicContact CH2-CG 3.95Å; W302-W324 HydrophobicContact CZ2-CB 3.62Å; W302-W324 AromaticContact CZ2-CD1 3.98Å; W302-W324 AromaticContact CZ2-CG 3.84Å; W302-W324 HydrophobicContact CZ2-CG 3.84Å; L313-W324 HydrophobicContact CB-CZ2 4.01Å; L313-W324 HydrophobicContact CD2-CH2 4.02Å; L313-W324 HydrophobicContact CD2-CZ2 4.12Å; L313-W324 WeakPolarHBondContact O-CZ2 3.25Å
325M95.2Very high88.4Confident0 Ų036.1 Ų36.10%019%0.187CC..EExtended strand (participates in β ladder)trans-150167.3165.760.7175.511.600111.1L248 I280 L282 W291 D329 W330 F334L248-M325 HydrophobicContact CD1-CE 4.47Å; I280-M325 HydrophobicContact CG2-CG 3.8Å; I280-M325 PolarHBondContact N-O 3.49Å; I280-M325 PolarHBondContact O-N 2.9Å; L282-M325 HydrophobicContact CD1-SD 4.08Å; W291-M325 HydrophobicContact CB-CE 4.43Å; W291-M325 HydrophobicContact CD2-CE 3.32Å; W291-M325 HydrophobicContact CE3-CE 3.44Å; W291-M325 VanDerWaalsContact CE3-CE 3.44Å; W291-M325 HydrophobicContact CG-CE 3.81Å; W291-M325 HydrophobicContact CH2-CE 3.98Å; W291-M325 HydrophobicContact CZ2-CE 3.88Å; W291-M325 HydrophobicContact CZ3-CE 3.76Å; M325-D329 HydrophobicContact CE-CB 4.38Å; M325-W330 HydrophobicContact CG-CB 4.3Å; M325-W330 HydrophobicContact SD-CB 3.74Å; M325-W330 HydrophobicContact SD-CG 4.31Å; M325-F334 HydrophobicContact SD-CE2 3.97Å
326T95.1Very high89.2Confident12 Ų1236.4 Ų36.47%0.07419%0.189CC..EExtended strand (participates in β ladder)trans-68.6149.3170.875.40000110.1L277 M279 W295 E328 D329 W330L277-T326 HydrophobicContact CD1-CG2 4.2Å; M279-T326 HydrophobicContact SD-CG2 4.19Å; W295-T326 HydrophobicContact CG-CG2 4.35Å; T326-E328 PolarHBondContact O-N 2.55Å; T326-D329 PolarHBondContact O-N 3.33Å; T326-D329 WeakPolarHBondContact OG1-CB 3.39Å; T326-D329 PolarHBondContact OG1-N 2.71Å; T326-D329 PolarHBondContact OG1-OD2 2.91Å; T326-W330 PolarHBondContact O-N 2.77Å
327F95.6Very high90.4Very high2 Ų233.9 Ų33.91%0.00917%0.173CC..Hα-helixtrans-64.9-26.6175.5-167.3-103.5000112.4Q211 L214 F215 L218 F278 I280 W330 C331Q211-F327 HydrophobicContact CG-CD1 3.67Å; Q211-F327 HydrophobicContact CG-CE1 3.71Å; Q211-F327 VanDerWaalsContact O-CE1 3.29Å; Q211-F327 WeakPolarHBondContact O-CE1 3.1Å; L214-F327 HydrophobicContact CB-CZ 4.32Å; L214-F327 HydrophobicContact CD2-CZ 4Å; L214-F327 HydrophobicContact CG-CZ 3.97Å; F215-F327 HydrophobicContact CB-CD1 3.81Å; F215-F327 HydrophobicContact CB-CE1 3.68Å; F215-F327 HydrophobicContact CB-CE2 4.43Å; F215-F327 HydrophobicContact CB-CG 4.25Å; F215-F327 HydrophobicContact CB-CZ 4Å; F215-F327 HydrophobicContact CD2-CB 3.95Å; F215-F327 HydrophobicContact CD2-CD1 4.02Å; F215-F327 AromaticContact CD2-CD2 3.62Å; F215-F327 HydrophobicContact CD2-CD2 3.62Å; F215-F327 HydrophobicContact CD2-CE1 4.46Å; F215-F327 HydrophobicContact CD2-CE2 4.09Å; F215-F327 AromaticContact CD2-CG 3.56Å; F215-F327 HydrophobicContact CD2-CG 3.56Å; F215-F327 HydrophobicContact CD2-CZ 4.48Å; F215-F327 HydrophobicContact CE2-CB 4.4Å; F215-F327 HydrophobicContact CE2-CD2 4.38Å; F215-F327 HydrophobicContact CE2-CG 4.4Å; F215-F327 HydrophobicContact CG-CD1 4.34Å; F215-F327 HydrophobicContact CG-CG 4.32Å; L218-F327 HydrophobicContact CD1-CE2 3.75Å; L218-F327 HydrophobicContact CD1-CZ 3.94Å; F278-F327 HydrophobicContact CB-CB 3.9Å; F278-F327 PolarHBondContact O-N 2.85Å; I280-F327 HydrophobicContact CB-CD2 4.39Å; I280-F327 HydrophobicContact CD1-CD2 4.43Å; I280-F327 HydrophobicContact CD1-CE2 4.43Å; I280-F327 HydrophobicContact CG2-CD2 4.44Å; F327-W330 AromaticContact CD2-CE3 3.97Å; F327-W330 HydrophobicContact CD2-CE3 3.97Å; F327-W330 HydrophobicContact CE1-CE3 4.5Å; F327-W330 HydrophobicContact CE2-CD2 4.29Å; F327-W330 AromaticContact CE2-CE3 3.46Å; F327-W330 HydrophobicContact CE2-CE3 3.46Å; F327-W330 VanDerWaalsContact CE2-CE3 3.46Å; F327-W330 AromaticContact CE2-CZ3 3.64Å; F327-W330 HydrophobicContact CE2-CZ3 3.64Å; F327-W330 AromaticContact CZ-CE3 3.77Å; F327-W330 HydrophobicContact CZ-CE3 3.77Å; F327-W330 AromaticContact CZ-CZ3 3.65Å; F327-W330 HydrophobicContact CZ-CZ3 3.65Å; F327-C331 VanDerWaalsContact CE1-SG 3.53Å; F327-C331 PolarHBondContact O-N 2.98Å; F327-C331 PolarHBondContact O-SG 3.31Å
328E94.6Very high91.3Very high97 Ų9730.8 Ų30.845%0.45315%0.154SC..Hα-helixtrans-67.1-48.6174.2-174.6-172.9161.900111.3T326 W330 C331 K332T326-E328 PolarHBondContact O-N 2.55Å; E328-W330 VanDerWaalsContact C-N 3.27Å; E328-W330 PolarHBondContact O-N 2.99Å; E328-C331 PolarHBondContact O-N 3.33Å; E328-K332 WeakPolarHBondContact O-CG 3.21Å; E328-K332 PolarHBondContact O-N 3.03Å; E328-K332 VanDerWaalsContact O-N 3.08Å; E328-K332 VanDerWaalsContact OE1-CE 3.25Å; E328-K332 WeakPolarHBondContact OE1-CE 3.29Å; E328-K332 IonicContact OE1-NZ 3.81Å; E328-K332 PolarHBondContact OE1-NZ 2.8Å
329D95.3Very high92.3Very high31 Ų3124.6 Ų24.617%0.16613%0.125CC..Hα-helixtrans-63.8-37.5176.3-65.6-39.8000111W291 M325 T326 C331 K332 N333W291-D329 HydrophobicContact CZ2-CB 4.27Å; M325-D329 HydrophobicContact CE-CB 4.38Å; T326-D329 PolarHBondContact O-N 3.33Å; T326-D329 WeakPolarHBondContact OG1-CB 3.39Å; T326-D329 PolarHBondContact OG1-N 2.71Å; T326-D329 PolarHBondContact OG1-OD2 2.91Å; D329-C331 PolarHBondContact O-N 3.4Å; D329-K332 PolarHBondContact O-N 3.16Å; D329-K332 VanDerWaalsContact O-N 3.12Å; D329-K332 IonicContact OD1-NZ 3.38Å; D329-N333 PolarHBondContact O-N 3.04Å; D329-N333 PolarHBondContact O-ND2 3.01Å
330W96.5Very high93.2Very high0 Ų019.1 Ų19.10%010%0.096CC..Hα-helixtrans-57.4-49.5172.8-177.577.1000111.9L199 L214 L218 C230 I280 M325 T326 F327 E328 K332 N333 F334 V337L199-W330 HydrophobicContact CD1-CE3 4.33Å; L199-W330 HydrophobicContact CD1-CH2 3.52Å; L199-W330 HydrophobicContact CD1-CZ2 3.91Å; L199-W330 HydrophobicContact CD1-CZ3 3.74Å; L199-W330 HydrophobicContact CD2-CH2 3.87Å; L199-W330 HydrophobicContact CD2-CZ3 3.88Å; L199-W330 HydrophobicContact CG-CH2 4.3Å; L199-W330 HydrophobicContact CG-CZ3 4.5Å; L214-W330 HydrophobicContact CD2-CH2 4.47Å; L214-W330 HydrophobicContact CD2-CZ3 3.97Å; L218-W330 HydrophobicContact CD1-CH2 4.16Å; L218-W330 HydrophobicContact CD1-CZ3 4.3Å; C230-W330 HydrophobicContact CB-CZ2 3.81Å; I280-W330 HydrophobicContact CD1-CD2 4.19Å; I280-W330 HydrophobicContact CD1-CG 4.3Å; I280-W330 HydrophobicContact CG2-CB 3.76Å; I280-W330 HydrophobicContact CG2-CG 3.92Å; M325-W330 HydrophobicContact CG-CB 4.3Å; M325-W330 HydrophobicContact SD-CB 3.74Å; M325-W330 HydrophobicContact SD-CG 4.31Å; T326-W330 PolarHBondContact O-N 2.77Å; F327-W330 AromaticContact CD2-CE3 3.97Å; F327-W330 HydrophobicContact CD2-CE3 3.97Å; F327-W330 HydrophobicContact CE1-CE3 4.5Å; F327-W330 HydrophobicContact CE2-CD2 4.29Å; F327-W330 AromaticContact CE2-CE3 3.46Å; F327-W330 HydrophobicContact CE2-CE3 3.46Å; F327-W330 VanDerWaalsContact CE2-CE3 3.46Å; F327-W330 AromaticContact CE2-CZ3 3.64Å; F327-W330 HydrophobicContact CE2-CZ3 3.64Å; F327-W330 AromaticContact CZ-CE3 3.77Å; F327-W330 HydrophobicContact CZ-CE3 3.77Å; F327-W330 AromaticContact CZ-CZ3 3.65Å; F327-W330 HydrophobicContact CZ-CZ3 3.65Å; E328-W330 VanDerWaalsContact C-N 3.27Å; E328-W330 PolarHBondContact O-N 2.99Å; W330-K332 PolarHBondContact O-N 3.23Å; W330-N333 PolarHBondContact O-N 3.43Å; W330-F334 AromaticContact CD1-CD2 3.17Å; W330-F334 AromaticContact CD1-CE2 3.49Å; W330-F334 VanDerWaalsContact CD1-CE2 3.49Å; W330-F334 AromaticContact CD1-CG 3.68Å; W330-F334 AromaticContact CG-CD2 3.94Å; W330-F334 HydrophobicContact CG-CD2 3.94Å; W330-F334 HydrophobicContact CG-CG 4.46Å; W330-F334 HydrophobicContact CZ2-CB 4.5Å; W330-F334 AromaticContact NE1-CD1 3.85Å; W330-F334 AromaticContact NE1-CD2 3.48Å; W330-F334 AromaticContact NE1-CE2 3.92Å; W330-F334 AromaticContact NE1-CG 3.44Å; W330-F334 WeakPolarHBondContact O-CB 3.21Å; W330-F334 WeakPolarHBondContact O-CD2 3.32Å; W330-F334 PolarHBondContact O-N 3.12Å; W330-V337 HydrophobicContact CH2-CB 3.68Å; W330-V337 HydrophobicContact CH2-CG1 3.91Å; W330-V337 HydrophobicContact CH2-CG2 3.96Å; W330-V337 HydrophobicContact CZ2-CB 3.85Å; W330-V337 HydrophobicContact CZ2-CG2 3.98Å
331C95.6Very high93.9Very high4 Ų419.9 Ų19.93%0.02710%0.097CC..Hα-helixtrans-64.5-22.1176.8-67.20000114F327 E328 D329F327-C331 VanDerWaalsContact CE1-SG 3.53Å; F327-C331 PolarHBondContact O-N 2.98Å; F327-C331 PolarHBondContact O-SG 3.31Å; E328-C331 PolarHBondContact O-N 3.33Å; D329-C331 PolarHBondContact O-N 3.4Å
332K93.9Very high94Very high78 Ų7822.8 Ų22.834%0.33911%0.112SC..Hα-helixtrans-81.5-32.9177.1-74.5169.7-175.4165.60112.8R205 E328 D329 W330R205-K332 HydrophobicContact CG-CG 3.99Å; E328-K332 WeakPolarHBondContact O-CG 3.21Å; E328-K332 PolarHBondContact O-N 3.03Å; E328-K332 VanDerWaalsContact O-N 3.08Å; E328-K332 VanDerWaalsContact OE1-CE 3.25Å; E328-K332 WeakPolarHBondContact OE1-CE 3.29Å; E328-K332 IonicContact OE1-NZ 3.81Å; E328-K332 PolarHBondContact OE1-NZ 2.8Å; D329-K332 PolarHBondContact O-N 3.16Å; D329-K332 VanDerWaalsContact O-N 3.12Å; D329-K332 IonicContact OD1-NZ 3.38Å; W330-K332 PolarHBondContact O-N 3.23Å
333N94.8Very high93.5Very high52 Ų5223.4 Ų23.428%0.27812%0.117SC..Hα-helixtrans-103.4-29.1-170.4-68.1-75.5000113.5L248 D329 W330L248-N333 HydrophobicContact CD1-CB 3.7Å; D329-N333 PolarHBondContact O-N 3.04Å; D329-N333 PolarHBondContact O-ND2 3.01Å; W330-N333 PolarHBondContact O-N 3.43Å
334F95.3Very high92.7Very high5 Ų525.8 Ų25.82%0.02213%0.13CC..  trans-93.3151.3179.5-72.6-99.8000112L199 C230 I232 L248 Y254 L282 M325 W330L199-F334 HydrophobicContact CD1-CB 3.83Å; C230-F334 HydrophobicContact CB-CD1 3.94Å; C230-F334 HydrophobicContact CB-CE1 4.4Å; C230-F334 VanDerWaalsContact SG-CE1 3.54Å; I232-F334 HydrophobicContact CD1-CD1 4.4Å; I232-F334 HydrophobicContact CD1-CE1 4.17Å; I232-F334 HydrophobicContact CD1-CZ 4.26Å; I232-F334 HydrophobicContact CG1-CD1 3.71Å; I232-F334 HydrophobicContact CG1-CE1 3.88Å; I232-F334 HydrophobicContact CG1-CG 4.13Å; I232-F334 HydrophobicContact CG1-CZ 4.42Å; L248-F334 HydrophobicContact CD1-CE2 4.01Å; L248-F334 HydrophobicContact CD1-CZ 4.45Å; L248-F334 HydrophobicContact CD2-CE2 4.4Å; L248-F334 HydrophobicContact CD2-CZ 4.24Å; Y254-F334 AromaticContact CD2-CE1 3.76Å; Y254-F334 HydrophobicContact CD2-CE1 3.76Å; Y254-F334 HydrophobicContact CD2-CZ 4.25Å; Y254-F334 HydrophobicContact CE2-CE1 4.36Å; Y254-F334 HydrophobicContact CG-CE1 4.09Å; Y254-F334 HydrophobicContact CG-CZ 4.36Å; L282-F334 HydrophobicContact CD1-CE1 4.21Å; L282-F334 HydrophobicContact CD1-CE2 3.63Å; L282-F334 HydrophobicContact CD1-CZ 3.37Å; M325-F334 HydrophobicContact SD-CE2 3.97Å; W330-F334 AromaticContact CD1-CD2 3.17Å; W330-F334 AromaticContact CD1-CE2 3.49Å; W330-F334 VanDerWaalsContact CD1-CE2 3.49Å; W330-F334 AromaticContact CD1-CG 3.68Å; W330-F334 AromaticContact CG-CD2 3.94Å; W330-F334 HydrophobicContact CG-CD2 3.94Å; W330-F334 HydrophobicContact CG-CG 4.46Å; W330-F334 HydrophobicContact CZ2-CB 4.5Å; W330-F334 AromaticContact NE1-CD1 3.85Å; W330-F334 AromaticContact NE1-CD2 3.48Å; W330-F334 AromaticContact NE1-CE2 3.92Å; W330-F334 AromaticContact NE1-CG 3.44Å; W330-F334 WeakPolarHBondContact O-CB 3.21Å; W330-F334 WeakPolarHBondContact O-CD2 3.32Å; W330-F334 PolarHBondContact O-N 3.12Å
335T94.1Very high91.7Very high16 Ų1628.8 Ų28.810%0.09815%0.148CC..  trans-107.8-33.8-177.860.20000112.1L199 I200 S231 I232 T233L199-T335 VanDerWaalsContact CB-O 3.31Å; L199-T335 WeakPolarHBondContact CB-O 3.31Å; L199-T335 PolarHBondContact N-O 3.19Å; I200-T335 HydrophobicContact CD1-CG2 3.79Å; I200-T335 HydrophobicContact CG1-CG2 4.46Å; S231-T335 PolarHBondContact O-N 2.89Å; S231-T335 VanDerWaalsContact O-N 3.14Å; S231-T335 PolarHBondContact O-OG1 3.08Å; I232-T335 HydrophobicContact CG2-CG2 4.36Å; T233-T335 WeakPolarHBondContact CB-OG1 3.47Å; T233-T335 PolarHBondContact N-OG1 2.88Å; T233-T335 PolarHBondContact OG1-OG1 3.21Å
336D94Very high90.5Very high45 Ų4531.5 Ų31.524%0.24117%0.167CC..EExtended strand (participates in β ladder)trans-138.5145-171.4-57.8-85.2000111.3C230 S231 T233C230-D336 VanDerWaalsContact CA-O 3.25Å; C230-D336 WeakPolarHBondContact CA-O 3.29Å; C230-D336 VanDerWaalsContact CB-O 3.27Å; C230-D336 WeakPolarHBondContact CB-O 3.48Å; S231-D336 PolarHBondContact N-O 3.44Å; S231-D336 PolarHBondContact O-N 3.03Å; T233-D336 PolarHBondContact OG1-OD2 2.63Å
337V96Very high88.8Confident0 Ų040.6 Ų40.60%020%0.202CC..EExtended strand (participates in β ladder)trans-133.6131.3170.563.80000111.4S196 V197 L199 L218 I228 S229 C230 W330 I339S196-V337 CarbonylContact C-O 3.55Å; S196-V337 WeakPolarHBondContact CA-O 3.27Å; V197-V337 HydrophobicContact CB-CG1 3.74Å; V197-V337 HydrophobicContact CG1-CG1 4.42Å; V197-V337 HydrophobicContact CG2-CG1 4.45Å; V197-V337 PolarHBondContact N-O 3.14Å; V197-V337 PolarHBondContact O-N 3.47Å; L199-V337 HydrophobicContact CD2-CG1 3.99Å; L218-V337 HydrophobicContact CD2-CG2 4.25Å; I228-V337 HydrophobicContact CG2-CG2 3.54Å; S229-V337 WeakPolarHBondContact O-CG2 3.49Å; C230-V337 HydrophobicContact CB-CB 4.34Å; C230-V337 HydrophobicContact CB-CG2 4.34Å; W330-V337 HydrophobicContact CH2-CB 3.68Å; W330-V337 HydrophobicContact CH2-CG1 3.91Å; W330-V337 HydrophobicContact CH2-CG2 3.96Å; W330-V337 HydrophobicContact CZ2-CB 3.85Å; W330-V337 HydrophobicContact CZ2-CG2 3.98Å; V337-I339 HydrophobicContact CG1-CD1 4.48Å; V337-I339 HydrophobicContact CG1-CG1 4.39Å; V337-I339 HydrophobicContact CG2-CG1 4.19Å
338D95Very high87.2Confident21 Ų2150.1 Ų50.111%0.11224%0.243CC..EExtended strand (participates in β ladder)trans-102.3115.2176.5-79.1-29.4000109.6A183 S196 I228 S229A183-D338 HydrophobicContact CB-CB 3.88Å; A183-D338 PolarHBondContact N-OD2 3.45Å; S196-D338 VanDerWaalsContact CB-OD1 3.3Å; S196-D338 WeakPolarHBondContact CB-OD1 3.49Å; S196-D338 PolarHBondContact OG-OD1 2.85Å; I228-D338 WeakPolarHBondContact CA-O 3.45Å; S229-D338 PolarHBondContact N-O 3.24Å; S229-D338 PolarHBondContact O-N 2.87Å; S229-D338 WeakPolarHBondContact OG-CB 3.44Å
339I95Very high85.7Confident1 Ų147.2 Ų47.21%0.00523%0.234CC..EExtended strand (participates in β ladder)trans-108.8100-174.4-47.8172.2000109.4E195 V197 L214 L218 V221 I228 V337 R341E195-I339 HydrophobicContact CB-CB 4.49Å; E195-I339 PolarHBondContact N-O 3.27Å; E195-I339 PolarHBondContact O-N 2.73Å; V197-I339 HydrophobicContact CG2-CD1 3.8Å; L214-I339 HydrophobicContact CD1-CD1 4.47Å; L218-I339 HydrophobicContact CD2-CD1 3.48Å; L218-I339 VanDerWaalsContact CD2-CD1 3.48Å; L218-I339 HydrophobicContact CD2-CG1 3.58Å; L218-I339 HydrophobicContact CD2-CG2 4.33Å; V221-I339 HydrophobicContact CB-CG2 4.15Å; V221-I339 HydrophobicContact CG1-CG2 3.78Å; V221-I339 HydrophobicContact CG2-CG2 3.83Å; I228-I339 HydrophobicContact CG1-CG2 4.48Å; V337-I339 HydrophobicContact CG1-CD1 4.48Å; V337-I339 HydrophobicContact CG1-CG1 4.39Å; V337-I339 HydrophobicContact CG2-CG1 4.19Å; I339-R341 HydrophobicContact CG2-CG 4.4Å; I339-R341 VanDerWaalsContact CG2-CZ 3.49Å; I339-R341 PolarHBondContact O-NH1 3.18Å
340C94.2Very high84.1Confident0 Ų053.6 Ų53.60%027%0.266CS..EExtended strand (participates in β ladder)trans-96.2106.2-178-65.40000111.6I186 A192 G226 L227I186-C340 HydrophobicContact CB-CB 4.23Å; I186-C340 HydrophobicContact CD1-CB 4.49Å; I186-C340 HydrophobicContact CG2-CB 3.34Å; I186-C340 VanDerWaalsContact CG2-SG 3.53Å; A192-C340 HydrophobicContact CB-CB 4.09Å; G226-C340 CarbonylContact C-O 3.54Å; G226-C340 WeakPolarHBondContact CA-O 3.36Å; L227-C340 HydrophobicContact CB-CB 4.32Å; L227-C340 PolarHBondContact N-O 3.35Å; L227-C340 WeakPolarHBondContact O-CA 3.28Å; L227-C340 VanDerWaalsContact O-CB 3.31Å; L227-C340 WeakPolarHBondContact O-CB 3.47Å; L227-C340 PolarHBondContact O-N 2.88Å
341R91.7Very high82.6Confident35 Ų3559.1 Ų59.113%0.13229%0.292CS..EExtended strand (participates in β ladder)trans-90.3122-175.4-65.8178.6-179.678.6-6.8111.4V193 E195 D217 V221 I339 V343V193-R341 PolarHBondContact N-O 3.39Å; V193-R341 VanDerWaalsContact N-O 3.11Å; V193-R341 PolarHBondContact O-N 3.05Å; E195-R341 VanDerWaalsContact CB-NH1 3.35Å; E195-R341 IonicContact OE2-CZ 2.66Å; E195-R341 IonicContact OE2-NH1 2.6Å; E195-R341 PolarHBondContact OE2-NH1 3.28Å; E195-R341 IonicContact OE2-NH2 2.82Å; E195-R341 PolarHBondContact OE2-NH2 3.09Å; D217-R341 IonicContact OD2-NH2 3.88Å; D217-R341 PolarHBondContact OD2-NH2 2.75Å; V221-R341 HydrophobicContact CG1-CG 4.22Å; V221-R341 HydrophobicContact CG2-CG 4.01Å; I339-R341 HydrophobicContact CG2-CG 4.4Å; I339-R341 VanDerWaalsContact CG2-CZ 3.49Å; I339-R341 PolarHBondContact O-NH1 3.18Å; R341-V343 HydrophobicContact CB-CG2 4.23Å; R341-V343 PolarHBondContact O-N 2.65Å; R341-V343 VanDerWaalsContact O-N 3.14Å
342I86.3Confident81.5Confident61 Ų6162.8 Ų62.831%0.31331%0.308SS..  trans-76.895.8162.5-53.3-59.8000107.5L96 T190 A192 G225 N344L96-I342 HydrophobicContact CD1-CD1 3.82Å; L96-I342 HydrophobicContact CD1-CG1 4.09Å; L96-I342 HydrophobicContact CD2-CD1 4.23Å; T190-I342 HydrophobicContact CG2-CD1 4.24Å; A192-I342 HydrophobicContact CB-CD1 3.99Å; G225-I342 VanDerWaalsContact O-CG1 3.31Å; G225-I342 WeakPolarHBondContact O-CG1 3.42Å; I342-N344 PolarHBondContact O-N 3.44Å
343V79.1Confident80.8Confident28 Ų2861.5 Ų61.517%0.1731%0.306CS..  trans-76.9113-175.4-173.50000109.8V193 R341 T345 W354 F490V193-V343 HydrophobicContact CB-CG2 4.37Å; V193-V343 HydrophobicContact CG2-CG2 3.91Å; R341-V343 HydrophobicContact CB-CG2 4.23Å; R341-V343 PolarHBondContact O-N 2.65Å; R341-V343 VanDerWaalsContact O-N 3.14Å; V343-T345 HydrophobicContact CG1-CG2 4.49Å; V343-T345 PolarHBondContact O-N 2.95Å; V343-W354 HydrophobicContact CG1-CB 3.58Å; V343-W354 VanDerWaalsContact CG1-CD1 3.47Å; V343-W354 HydrophobicContact CG1-CD2 4.42Å; V343-W354 HydrophobicContact CG1-CG 3.54Å; V343-F490 HydrophobicContact CB-CD1 4.18Å; V343-F490 HydrophobicContact CB-CE1 3.89Å; V343-F490 HydrophobicContact CG1-CD1 3.61Å; V343-F490 HydrophobicContact CG1-CE1 3.83Å; V343-F490 HydrophobicContact CG1-CG 4.49Å; V343-F490 HydrophobicContact CG2-CD1 4.3Å; V343-F490 HydrophobicContact CG2-CE1 4Å; V343-F490 HydrophobicContact CG2-CZ 4.38Å
344N76.1Confident80.3Confident50 Ų5060.7 Ų60.727%0.26730%0.299SS..  trans-67.4116.7176-175.33000110.9I342 S346 S349 T353 W354I342-N344 PolarHBondContact O-N 3.44Å; N344-S346 WeakPolarHBondContact OD1-CB 3.48Å; N344-S346 PolarHBondContact OD1-N 3.27Å; N344-S349 VanDerWaalsContact ND2-CB 3.33Å; N344-S349 WeakPolarHBondContact ND2-CB 3.46Å; N344-S349 PolarHBondContact ND2-OG 3.35Å; N344-T353 CarbonylContact O-C 3.56Å; N344-T353 WeakPolarHBondContact O-CA 3.47Å; N344-W354 PolarHBondContact O-N 2.91Å
345T73.3Confident80Confident66 Ų6661.4 Ų61.441%0.40530%0.303SS..  trans-1176.8178.153.10000112.1V343 K356V343-T345 HydrophobicContact CG1-CG2 4.49Å; V343-T345 PolarHBondContact O-N 2.95Å; T345-K356 HydrophobicContact CG2-CB 3.72Å; T345-K356 HydrophobicContact CG2-CD 4.44Å
346S69.6Low79.9Confident58 Ų5864.6 Ų64.641%0.40632%0.315SS..  trans-75.4125.2-176.7-179.60000111.4N344 F348 T353N344-S346 WeakPolarHBondContact OD1-CB 3.48Å; N344-S346 PolarHBondContact OD1-N 3.27Å; S346-F348 PolarHBondContact O-N 3.22Å; S346-F348 PolarHBondContact OG-N 3.32Å; S346-T353 WeakPolarHBondContact O-CG2 3.48Å
347Y60.2Low79.9Confident202 Ų20266.8 Ų66.879%0.79232%0.323SS*.THydrogen-bonded Turntrans-65.9-16.6177.6-68.5-77.9000114.1
348F61.4Low79.9Confident202 Ų20269.6 Ų69.689%0.88634%0.336SS*.THydrogen-bonded Turntrans-10628.6-175.4-61.5-74.2000113.5S346S346-F348 PolarHBondContact O-N 3.22Å; S346-F348 PolarHBondContact OG-N 3.32Å
349S61.5Low80Confident36 Ų3670.7 Ų70.725%0.25234%0.341SS..  trans-99.9139.7-177.5161.90000112.6N344 H351N344-S349 VanDerWaalsContact ND2-CB 3.33Å; N344-S349 WeakPolarHBondContact ND2-CB 3.46Å; N344-S349 PolarHBondContact ND2-OG 3.35Å; S349-H351 VanDerWaalsContact C-N 3.26Å; S349-H351 PolarHBondContact O-N 2.86Å; S349-H351 PolarHBondContact OG-N 3.03Å; S349-H351 PolarHBondContact OG-O 3.13Å
350I62.6Low80.1Confident165 Ų16575.3 Ų75.385%0.84636%0.363SS*.SBendtrans-74.2-15.6169.360.2171.4000113.2
351H65.3Low80.3Confident117 Ų11776 Ų7654%0.54237%0.37SS..SBendtrans-96.1159.4176.8-59.5-56.3000112S349 T353S349-H351 VanDerWaalsContact C-N 3.26Å; S349-H351 PolarHBondContact O-N 2.86Å; S349-H351 PolarHBondContact OG-N 3.03Å; S349-H351 PolarHBondContact OG-O 3.13Å; H351-T353 WeakPolarHBondContact O-CG2 3.36Å; H351-T353 PolarHBondContact O-N 3.1Å
352K72.4Confident80.6Confident81 Ų8175.9 Ų75.935%0.35238%0.377SS..PPolyproline II helixtrans-46.1122.3175.3-179.3175.5-179.2173.30111.1W354 D492K352-W354 HydrophobicContact CD-CZ2 4.5Å; K352-D492 WeakPolarHBondContact CE-OD1 3.47Å; K352-D492 IonicContact NZ-OD1 3.14Å; K352-D492 PolarHBondContact NZ-OD1 3.01Å; K352-D492 IonicContact NZ-OD2 3.28Å; K352-D492 PolarHBondContact NZ-OD2 3.14Å
353T79.1Confident81.1Confident51 Ų5173 Ų7331%0.31336%0.362SS..PPolyproline II helixtrans-100.9154174.758.10000109.5N344 S346 H351N344-T353 CarbonylContact O-C 3.56Å; N344-T353 WeakPolarHBondContact O-CA 3.47Å; S346-T353 WeakPolarHBondContact O-CG2 3.48Å; H351-T353 WeakPolarHBondContact O-CG2 3.36Å; H351-T353 PolarHBondContact O-N 3.1Å
354W84.8Confident82Confident34 Ų3474.6 Ų74.613%0.12937%0.372CS..  trans-118.1140.7175.4-68.385000109.5V343 N344 K352 K400 L402 F490V343-W354 HydrophobicContact CG1-CB 3.58Å; V343-W354 VanDerWaalsContact CG1-CD1 3.47Å; V343-W354 HydrophobicContact CG1-CD2 4.42Å; V343-W354 HydrophobicContact CG1-CG 3.54Å; N344-W354 PolarHBondContact O-N 2.91Å; K352-W354 HydrophobicContact CD-CZ2 4.5Å; W354-K400 HydrophobicContact CH2-CB 4.17Å; W354-K400 HydrophobicContact CH2-CD 4.08Å; W354-K400 HydrophobicContact CH2-CG 4.05Å; W354-K400 VanDerWaalsContact CZ3-O 3.28Å; W354-K400 WeakPolarHBondContact CZ3-O 3Å; W354-L402 HydrophobicContact CE3-CD1 4.45Å; W354-L402 HydrophobicContact CH2-CD1 3.8Å; W354-L402 HydrophobicContact CH2-CD2 4.22Å; W354-L402 HydrophobicContact CH2-CG 3.82Å; W354-L402 HydrophobicContact CZ2-CD1 3.98Å; W354-L402 HydrophobicContact CZ2-CG 4.49Å; W354-L402 HydrophobicContact CZ3-CD1 4.05Å; W354-L402 HydrophobicContact CZ3-CG 3.88Å; W354-F490 HydrophobicContact CB-CD1 4.42Å; W354-F490 HydrophobicContact CD2-CB 4.35Å; W354-F490 HydrophobicContact CE3-CB 3.75Å; W354-F490 HydrophobicContact CZ3-CB 4.31Å
355E88Confident83Confident21 Ų2179.4 Ų79.410%0.09839%0.39CS..EExtended strand (participates in β ladder)trans-75.8125160.4-167-116.2-179.100108.4K357 F490 T491 P494 S495E355-K357 WeakPolarHBondContact OE1-CE 3.39Å; E355-K357 WeakPolarHBondContact OE1-CG 3.45Å; E355-F490 VanDerWaalsContact O-CA 3.26Å; E355-F490 WeakPolarHBondContact O-CA 3.2Å; E355-T491 PolarHBondContact N-O 3.41Å; E355-T491 PolarHBondContact O-N 2.82Å; E355-T491 VanDerWaalsContact O-N 3.14Å; E355-T491 PolarHBondContact OE2-OG1 3.33Å; E355-P494 HydrophobicContact CG-CB 4.31Å; E355-P494 HydrophobicContact CG-CG 4.29Å; E355-S495 PolarHBondContact OE2-N 3.5Å; E355-S495 PolarHBondContact OE2-OG 2.87Å
356K92.4Very high84.1Confident82 Ų8279.4 Ų79.436%0.35739%0.388SS..EExtended strand (participates in β ladder)trans-108.8129.9174.9175.8-175.4176.3-178.40109.5T345 L489 F490T345-K356 HydrophobicContact CG2-CB 3.72Å; T345-K356 HydrophobicContact CG2-CD 4.44Å; K356-L489 WeakPolarHBondContact CA-O 2.91Å; K356-F490 HydrophobicContact CB-CD1 3.86Å; K356-F490 HydrophobicContact CB-CE1 3.75Å; K356-F490 HydrophobicContact CD-CE1 3.72Å; K356-F490 HydrophobicContact CD-CZ 4.1Å; K356-F490 HydrophobicContact CG-CD1 4.06Å; K356-F490 HydrophobicContact CG-CE1 3.51Å; K356-F490 HydrophobicContact CG-CZ 3.98Å
357K94.4Very high85.3Confident92 Ų9282 Ų8240%0.441%0.406SS..EExtended strand (participates in β ladder)trans-122.3136.4162.5-70-71.4176.5-179.10110.2E355 R488 L489 L497E355-K357 WeakPolarHBondContact OE1-CE 3.39Å; E355-K357 WeakPolarHBondContact OE1-CG 3.45Å; K357-R488 CarbonylContact O-C 3.47Å; K357-R488 WeakPolarHBondContact O-CA 3.24Å; K357-L489 PolarHBondContact N-O 3.05Å; K357-L489 PolarHBondContact O-N 2.87Å; K357-L497 HydrophobicContact CB-CB 3.86Å; K357-L497 HydrophobicContact CB-CD2 3.7Å; K357-L497 HydrophobicContact CB-CG 4.38Å; K357-L497 HydrophobicContact CG-CB 4.12Å
358M95.2Very high87Confident58 Ų5877.8 Ų77.829%0.28639%0.393SS..EExtended strand (participates in β ladder)trans-124.3129.8177.5-176.2171.976.100108.7W126 L487 R488W126-M358 HydrophobicContact CZ2-SD 4.39Å; M358-L487 CarbonylContact C-O 3.51Å; M358-L487 VanDerWaalsContact CA-O 3.31Å; M358-L487 WeakPolarHBondContact CA-O 3.35Å; M358-R488 HydrophobicContact CB-CG 4.24Å; M358-R488 HydrophobicContact CG-CG 3.85Å; M358-R488 HydrophobicContact SD-CG 4.2Å
359M97.1Very high88.5Confident45 Ų4571.7 Ų71.722%0.22237%0.374CS..EExtended strand (participates in β ladder)trans-120.5129.7178.4-58.6-62.2-63.900108.6Y390 I486 L487 L497 E499M359-Y390 HydrophobicContact CB-CD1 4.12Å; M359-Y390 HydrophobicContact CB-CE1 3.62Å; M359-Y390 HydrophobicContact CE-CD1 4.25Å; M359-Y390 HydrophobicContact CE-CE1 3.97Å; M359-Y390 HydrophobicContact CG-CD1 3.92Å; M359-Y390 HydrophobicContact CG-CE1 3.91Å; M359-I486 WeakPolarHBondContact O-CA 3.25Å; M359-L487 HydrophobicContact CB-CB 4.4Å; M359-L487 PolarHBondContact N-O 3.42Å; M359-L487 PolarHBondContact O-N 2.86Å; M359-L497 HydrophobicContact CG-CD2 3.59Å; M359-L497 HydrophobicContact CG-CG 3.98Å; M359-E499 HydrophobicContact CE-CB 4.47Å
360H97.4Very high90Very high97 Ų9773.8 Ų73.845%0.44938%0.382SS..EExtended strand (participates in β ladder)trans-86.6132.2166.2-62.190.2000108.3I486H360-I486 WeakPolarHBondContact CD2-CG2 3.22Å
361G97.7Very high91.6Very high15 Ų1570.3 Ų70.316%0.15537%0.365CS..EExtended strand (participates in β ladder)trans-140.4172.3-179.500000111.7Y390 K484 F485G361-Y390 WeakPolarHBondContact CA-OH 3.38Å; G361-K484 WeakPolarHBondContact O-CA 3.27Å; G361-F485 PolarHBondContact N-O 2.78Å; G361-F485 PolarHBondContact O-N 2.91Å; G361-F485 VanDerWaalsContact O-O 3.05Å
362A98Very high93.1Very high33 Ų3365.5 Ų65.527%0.27334%0.343SS..EExtended strand (participates in β ladder)trans-149.4141.1175.500000111T364 P388 T483 K484A362-T364 HydrophobicContact CB-CG2 3.89Å; A362-P388 WeakPolarHBondContact O-CG 3.44Å; A362-T483 WeakPolarHBondContact CA-O 3.28Å; A362-K484 HydrophobicContact CB-CG 4.2Å
363W98.3Very high94.3Very high0 Ų063 Ų630%033%0.331CS..EExtended strand (participates in β ladder)trans-82117.9161.2-58.1-74.5000107.1R373 L405 I424 P474 T475 T476 I481 I482 T483 F485W363-R373 WeakPolarHBondContact CA-O 3.5Å; W363-R373 VanDerWaalsContact CD1-O 3.23Å; W363-L405 HydrophobicContact CH2-CD2 4.4Å; W363-L405 HydrophobicContact CZ2-CD2 4.29Å; W363-I424 HydrophobicContact CH2-CB 4.25Å; W363-I424 HydrophobicContact CH2-CG2 3.62Å; W363-I424 HydrophobicContact CZ2-CG2 4.46Å; W363-I424 HydrophobicContact CZ3-CG2 4.06Å; W363-P474 HydrophobicContact CZ2-CB 4.24Å; W363-P474 PolarHBondContact NE1-O 3.02Å; W363-T475 VanDerWaalsContact CZ2-C 3.43Å; W363-T476 HydrophobicContact CD2-CG2 3.79Å; W363-T476 HydrophobicContact CE3-CG2 3.71Å; W363-T476 HydrophobicContact CG-CG2 4.34Å; W363-T476 HydrophobicContact CH2-CG2 4.19Å; W363-T476 HydrophobicContact CZ2-CG2 4.3Å; W363-T476 HydrophobicContact CZ3-CG2 3.91Å; W363-I481 WeakPolarHBondContact CB-O 3.3Å; W363-I482 WeakPolarHBondContact O-CA 3.12Å; W363-I482 WeakPolarHBondContact O-CG2 3.29Å; W363-T483 HydrophobicContact CE3-CG2 3.33Å; W363-T483 HydrophobicContact CZ3-CG2 3.52Å; W363-T483 PolarHBondContact N-O 2.77Å; W363-T483 PolarHBondContact O-N 2.66Å; W363-F485 AromaticContact CD2-CD1 3.67Å; W363-F485 HydrophobicContact CD2-CD1 3.67Å; W363-F485 AromaticContact CD2-CE1 3.97Å; W363-F485 HydrophobicContact CD2-CE1 3.97Å; W363-F485 AromaticContact CE2-CD1 3.67Å; W363-F485 AromaticContact CE2-CE1 3.84Å; W363-F485 AromaticContact CE3-CD1 3.66Å; W363-F485 HydrophobicContact CE3-CD1 3.66Å; W363-F485 HydrophobicContact CE3-CE1 4.4Å; W363-F485 HydrophobicContact CG-CD1 4.44Å; W363-F485 HydrophobicContact CG-CE1 4.33Å; W363-F485 HydrophobicContact CH2-CB 3.82Å; W363-F485 AromaticContact CH2-CD1 3.78Å; W363-F485 HydrophobicContact CH2-CD1 3.78Å; W363-F485 HydrophobicContact CH2-CG 4.02Å; W363-F485 HydrophobicContact CZ2-CB 4.48Å; W363-F485 AromaticContact CZ2-CD1 3.74Å; W363-F485 HydrophobicContact CZ2-CD1 3.74Å; W363-F485 HydrophobicContact CZ2-CE1 4.22Å; W363-F485 HydrophobicContact CZ2-CG 4.2Å; W363-F485 HydrophobicContact CZ3-CB 3.85Å; W363-F485 AromaticContact CZ3-CD1 3.74Å; W363-F485 HydrophobicContact CZ3-CD1 3.74Å; W363-F485 HydrophobicContact CZ3-CG 4.19Å
364T97.8Very high95.2Very high62 Ų6260.7 Ų60.738%0.3832%0.317SS..  trans-127.8147.7-176.255.40000109.7A362 N372 R373 S374A362-T364 HydrophobicContact CB-CG2 3.89Å; T364-N372 PolarHBondContact O-OD1 3.19Å; T364-R373 CarbonylContact O-C 3.55Å; T364-R373 WeakPolarHBondContact O-CA 3.46Å; T364-R373 PolarHBondContact O-N 2.91Å; T364-R373 WeakPolarHBondContact OG1-CB 3.23Å; T364-S374 PolarHBondContact O-N 3.04Å; T364-S374 PolarHBondContact O-OG 3.34Å
365K96.9Very high95.8Very high151 Ų15159.1 Ų59.166%0.65731%0.311SS*.  trans-94.9134.5179.5-172174.4-178.8177.70110.2N372 I482K365-N372 WeakPolarHBondContact CA-OD1 3.34Å; K365-I482 HydrophobicContact CB-CD1 3.64Å; K365-I482 HydrophobicContact CB-CG1 4.02Å
366N97.2Very high96.3Very high65 Ų6558.1 Ų58.135%0.34831%0.307SS..  trans-140.8148.8170.4-160.1-69.7000109.8E368 L371 N372N366-E368 VanDerWaalsContact C-N 3.33Å; N366-E368 WeakPolarHBondContact OD1-CB 3.3Å; N366-E368 PolarHBondContact OD1-N 3.01Å; N366-L371 HydrophobicContact CB-CB 3.94Å; N366-N372 HydrophobicContact CB-CB 4.34Å; N366-N372 PolarHBondContact N-OD1 3.42Å
367S94.4Very high96.6Very high112 Ų11254.3 Ų54.378%0.78329%0.291SS*.SBendtrans-69.7-32.5174.150.80000112.2P369S367-P369 WeakPolarHBondContact O-CD 3.43Å
368E95.4Very high96.7Very high114 Ų11452.3 Ų52.353%0.53328%0.282SS..SBendtrans-78.8117.7175.9-63.1-59.5155.100110.2N366 L370 L371 N372N366-E368 VanDerWaalsContact C-N 3.33Å; N366-E368 WeakPolarHBondContact OD1-CB 3.3Å; N366-E368 PolarHBondContact OD1-N 3.01Å; E368-L370 VanDerWaalsContact C-N 3.27Å; E368-L370 PolarHBondContact O-N 3.14Å; E368-L370 VanDerWaalsContact O-N 3.16Å; E368-L371 HydrophobicContact CB-CB 4.14Å; E368-L371 HydrophobicContact CB-CD1 4.07Å; E368-L371 HydrophobicContact CB-CG 4.08Å; E368-L371 HydrophobicContact CG-CD1 4.38Å; E368-L371 CarbonylContact O-C 3.46Å; E368-L371 WeakPolarHBondContact O-CA 3.31Å; E368-L371 PolarHBondContact O-N 3.22Å; E368-N372 PolarHBondContact O-N 3.44Å
369P93.1Very high96.7Very high75 Ų7555.1 Ų55.149%0.48730%0.298SS..THydrogen-bonded Turntrans-56.5-35.9-174.4-29.136.5000114.6S367 L371 N372S367-P369 WeakPolarHBondContact O-CD 3.43Å; P369-L371 VanDerWaalsContact C-N 3.25Å; P369-L371 PolarHBondContact O-N 3.33Å; P369-N372 PolarHBondContact O-N 2.69Å
370L93.1Very high96.6Very high79 Ų7955.2 Ų55.241%0.41430%0.3SS..THydrogen-bonded Turntrans-70.9-20.3178.2-64.8178.3000113.2E368 R373E368-L370 VanDerWaalsContact C-N 3.27Å; E368-L370 PolarHBondContact O-N 3.14Å; E368-L370 VanDerWaalsContact O-N 3.16Å; L370-R373 PolarHBondContact O-NH1 2.88Å; L370-R373 PolarHBondContact O-NH2 3.47Å
371L95.6Very high96.4Very high93 Ų9360.7 Ų60.749%0.48732%0.316SS..THydrogen-bonded Turntrans-100.6-15.7177.5-58.4-177.2000112.6N366 E368 P369 R373N366-L371 HydrophobicContact CB-CB 3.94Å; E368-L371 HydrophobicContact CB-CB 4.14Å; E368-L371 HydrophobicContact CB-CD1 4.07Å; E368-L371 HydrophobicContact CB-CG 4.08Å; E368-L371 HydrophobicContact CG-CD1 4.38Å; E368-L371 CarbonylContact O-C 3.46Å; E368-L371 WeakPolarHBondContact O-CA 3.31Å; E368-L371 PolarHBondContact O-N 3.22Å; P369-L371 VanDerWaalsContact C-N 3.25Å; P369-L371 PolarHBondContact O-N 3.33Å; L371-R373 PolarHBondContact O-NH1 3.24Å
372N97.1Very high96.2Very high15 Ų1567.2 Ų67.28%0.0835%0.348CS..  trans-65.3142.2175.3-170.755.4000110.5T364 K365 N366 E368 P369 S374 Q386T364-N372 PolarHBondContact O-OD1 3.19Å; K365-N372 WeakPolarHBondContact CA-OD1 3.34Å; N366-N372 HydrophobicContact CB-CB 4.34Å; N366-N372 PolarHBondContact N-OD1 3.42Å; E368-N372 PolarHBondContact O-N 3.44Å; P369-N372 PolarHBondContact O-N 2.69Å; N372-S374 PolarHBondContact OD1-OG 2.81Å; N372-Q386 HydrophobicContact CB-CB 4.46Å; N372-Q386 PolarHBondContact ND2-OE1 3.33Å; N372-Q386 CarbonylContact O-C 3.47Å
373R98Very high96.2Very high29 Ų2967.6 Ų67.611%0.10935%0.347CS..  trans-130.612.2-178.9-62-69.7175.8-89.4-0.3112.7W363 T364 L370 L371 Q386 N387 P388W363-R373 WeakPolarHBondContact CA-O 3.5Å; W363-R373 VanDerWaalsContact CD1-O 3.23Å; T364-R373 CarbonylContact O-C 3.55Å; T364-R373 WeakPolarHBondContact O-CA 3.46Å; T364-R373 PolarHBondContact O-N 2.91Å; T364-R373 WeakPolarHBondContact OG1-CB 3.23Å; L370-R373 PolarHBondContact O-NH1 2.88Å; L370-R373 PolarHBondContact O-NH2 3.47Å; L371-R373 PolarHBondContact O-NH1 3.24Å; R373-Q386 WeakPolarHBondContact CA-O 3.46Å; R373-Q386 WeakPolarHBondContact CD-O 3.29Å; R373-N387 PolarHBondContact O-OD1 3.16Å; R373-P388 HydrophobicContact CB-CG 4.14Å; R373-P388 WeakPolarHBondContact O-CD 3.28Å
374S98Very high96.2Very high3 Ų367.8 Ų67.82%0.02135%0.347CS..  trans-118.967.2179.5600000110.1T364 N372 G480 I481T364-S374 PolarHBondContact O-N 3.04Å; T364-S374 PolarHBondContact O-OG 3.34Å; N372-S374 PolarHBondContact OD1-OG 2.81Å; S374-G480 PolarHBondContact O-N 2.75Å; S374-G480 WeakPolarHBondContact OG-CA 3.26Å; S374-I481 VanDerWaalsContact CB-O 3.32Å; S374-I481 WeakPolarHBondContact CB-O 3.36Å
375G97.9Very high96.2Very high0 Ų066.1 Ų66.10%034%0.336CS..  trans-89.9-5.4-169.800000115.7N380 T383 F384 N387G375-N380 WeakPolarHBondContact O-CB 3.37Å; G375-T383 WeakPolarHBondContact CA-O 3.2Å; G375-T383 CarbonylContact O-C 3.6Å; G375-T383 PolarHBondContact O-OG1 2.95Å; G375-F384 PolarHBondContact O-N 3.21Å; G375-N387 WeakPolarHBondContact CA-ND2 3.44Å; G375-N387 PolarHBondContact N-OD1 3.13Å
376G97.9Very high96.2Very high0 Ų060.6 Ų60.60%031%0.313CS..  trans73.5-179.2-177.900000113.6N387 T475 T476G376-N387 PolarHBondContact N-ND2 3.46Å; G376-N387 PolarHBondContact O-ND2 3.48Å; G376-T475 WeakPolarHBondContact O-CB 3.31Å; G376-T475 WeakPolarHBondContact O-CG2 3.46Å; G376-T476 CarbonylContact C-O 3.48Å; G376-T476 VanDerWaalsContact CA-O 3.23Å; G376-T476 WeakPolarHBondContact CA-O 3.23Å
377C97.5Very high96.3Very high3 Ų357.5 Ų57.52%0.0230%0.296CS..SBendtrans-70.7176.8-17870.20000112.7D379 N380 Y453 T476 Y477C377-D379 PolarHBondContact O-N 3.03Å; C377-N380 PolarHBondContact N-ND2 3.43Å; C377-N380 VanDerWaalsContact N-ND2 3.18Å; C377-N380 WeakPolarHBondContact O-CB 3.27Å; C377-N380 PolarHBondContact O-N 3.12Å; C377-N380 PolarHBondContact O-ND2 3.28Å; C377-N380 PolarHBondContact SG-ND2 2.98Å; C377-N380 VanDerWaalsContact SG-ND2 3.43Å; C377-Y453 HydrophobicContact CB-CD1 4.22Å; C377-Y453 HydrophobicContact CB-CE1 3.43Å; C377-Y453 VanDerWaalsContact CB-CE1 3.43Å; C377-Y453 HydrophobicContact CB-CE2 4.35Å; C377-T476 PolarHBondContact N-O 3.31Å; C377-Y477 HydrophobicContact CB-CD2 4.26Å; C377-Y477 PolarHBondContact N-O 3.07Å; C377-Y477 PolarHBondContact SG-O 3.47Å
378F96.3Very high96.5Very high50 Ų5052.3 Ų52.322%0.21926%0.259CS..THydrogen-bonded Turntrans-55.4-25.5-177.1-169.6-101.8000114.9N380 F384 E427 F429 L442 R447F378-N380 PolarHBondContact O-N 3.08Å; F378-F384 HydrophobicContact CB-CD2 4.38Å; F378-F384 HydrophobicContact CB-CE2 4.28Å; F378-F384 HydrophobicContact CD2-CD1 4.04Å; F378-F384 AromaticContact CD2-CE1 3.79Å; F378-F384 HydrophobicContact CD2-CE1 3.79Å; F378-F384 HydrophobicContact CD2-CE2 4.28Å; F378-F384 HydrophobicContact CD2-CG 4.41Å; F378-F384 AromaticContact CD2-CZ 3.93Å; F378-F384 HydrophobicContact CD2-CZ 3.93Å; F378-F384 HydrophobicContact CE2-CE1 4.28Å; F378-E427 HydrophobicContact CB-CG 4.21Å; F378-E427 HydrophobicContact CD2-CG 4.39Å; F378-F429 AromaticContact CD2-CZ 3.91Å; F378-F429 HydrophobicContact CD2-CZ 3.91Å; F378-F429 AromaticContact CE2-CE1 3.99Å; F378-F429 HydrophobicContact CE2-CE1 3.99Å; F378-F429 AromaticContact CE2-CZ 3.6Å; F378-F429 HydrophobicContact CE2-CZ 3.6Å; F378-L442 HydrophobicContact CE2-CD1 3.58Å; F378-L442 HydrophobicContact CZ-CD1 4.21Å; F378-R447 VanDerWaalsContact CD1-NH1 3.31Å
379D95.6Very high96.6Very high117 Ų11746.9 Ų46.963%0.62623%0.234SC*.THydrogen-bonded Turntrans-68.6-22.9177.7-61.3-30.1000112.2C377 R381C377-D379 PolarHBondContact O-N 3.03Å; D379-R381 VanDerWaalsContact C-N 3.25Å; D379-R381 PolarHBondContact O-N 3.49Å
380N96.1Very high96.9Very high47 Ų4743.3 Ų43.325%0.25121%0.211SC..  trans-83.861.9176.2-56.7-84.2000111G375 C377 F378 D382 T383 F384 Y477 P479G375-N380 WeakPolarHBondContact O-CB 3.37Å; C377-N380 PolarHBondContact N-ND2 3.43Å; C377-N380 VanDerWaalsContact N-ND2 3.18Å; C377-N380 WeakPolarHBondContact O-CB 3.27Å; C377-N380 PolarHBondContact O-N 3.12Å; C377-N380 PolarHBondContact O-ND2 3.28Å; C377-N380 PolarHBondContact SG-ND2 2.98Å; C377-N380 VanDerWaalsContact SG-ND2 3.43Å; F378-N380 PolarHBondContact O-N 3.08Å; N380-D382 PolarHBondContact O-N 2.97Å; N380-T383 PolarHBondContact O-N 3.42Å; N380-F384 WeakPolarHBondContact O-CB 3.36Å; N380-F384 PolarHBondContact O-N 3Å; N380-Y477 PolarHBondContact ND2-O 3.16Å; N380-P479 WeakPolarHBondContact OD1-CD 3.26Å
381R93.4Very high97.2Very high211 Ų21139.7 Ų39.780%0.79619%0.192SC*.THydrogen-bonded Turntrans-49-38.7-168.2-65.4-175.6179.7179.41.3115.1D379 T383D379-R381 VanDerWaalsContact C-N 3.25Å; D379-R381 PolarHBondContact O-N 3.49Å; R381-T383 VanDerWaalsContact C-N 3.34Å; R381-T383 PolarHBondContact O-N 3.43Å
382D93.6Very high97.3Very high153 Ų15335.3 Ų35.382%0.81817%0.169SC*.THydrogen-bonded Turntrans-74-24.8-176.4-58-35.6000113.6N380N380-D382 PolarHBondContact O-N 2.97Å
383T96.9Very high97.3Very high41 Ų4135.7 Ų35.725%0.25217%0.171SC..THydrogen-bonded Turntrans-119.4-15.1-172.957.20000113.3G375 N380 R381 L385 Q386G375-T383 WeakPolarHBondContact CA-O 3.2Å; G375-T383 CarbonylContact O-C 3.6Å; G375-T383 PolarHBondContact O-OG1 2.95Å; N380-T383 PolarHBondContact O-N 3.42Å; R381-T383 VanDerWaalsContact C-N 3.34Å; R381-T383 PolarHBondContact O-N 3.43Å; T383-L385 VanDerWaalsContact C-N 3.32Å; T383-L385 PolarHBondContact O-N 3.34Å; T383-Q386 WeakPolarHBondContact O-CA 3.38Å; T383-Q386 WeakPolarHBondContact O-CB 3.37Å; T383-Q386 VanDerWaalsContact O-CG 3.29Å; T383-Q386 WeakPolarHBondContact O-CG 3.41Å; T383-Q386 PolarHBondContact O-N 3.01Å
384F98.1Very high97.2Very high3 Ų334.5 Ų34.51%0.01317%0.167CC..G310 helixtrans-50.2-45.2-178.2169.9-106.1000113.7G375 F378 N380 Q386 N387 E427 F429 I473 T475G375-F384 PolarHBondContact O-N 3.21Å; F378-F384 HydrophobicContact CB-CD2 4.38Å; F378-F384 HydrophobicContact CB-CE2 4.28Å; F378-F384 HydrophobicContact CD2-CD1 4.04Å; F378-F384 AromaticContact CD2-CE1 3.79Å; F378-F384 HydrophobicContact CD2-CE1 3.79Å; F378-F384 HydrophobicContact CD2-CE2 4.28Å; F378-F384 HydrophobicContact CD2-CG 4.41Å; F378-F384 AromaticContact CD2-CZ 3.93Å; F378-F384 HydrophobicContact CD2-CZ 3.93Å; F378-F384 HydrophobicContact CE2-CE1 4.28Å; N380-F384 WeakPolarHBondContact O-CB 3.36Å; N380-F384 PolarHBondContact O-N 3Å; F384-Q386 PolarHBondContact O-N 3.49Å; F384-N387 WeakPolarHBondContact O-CB 3.39Å; F384-N387 PolarHBondContact O-N 3.02Å; F384-N387 PolarHBondContact O-ND2 3.39Å; F384-E427 HydrophobicContact CE2-CB 4.44Å; F384-E427 HydrophobicContact CE2-CG 3.85Å; F384-E427 HydrophobicContact CZ-CB 3.88Å; F384-E427 HydrophobicContact CZ-CG 3.7Å; F384-F429 AromaticContact CE1-CE2 3.76Å; F384-F429 HydrophobicContact CE1-CE2 3.76Å; F384-F429 AromaticContact CE1-CZ 3.89Å; F384-F429 HydrophobicContact CE1-CZ 3.89Å; F384-F429 AromaticContact CZ-CE2 3.77Å; F384-F429 HydrophobicContact CZ-CE2 3.77Å; F384-F429 HydrophobicContact CZ-CZ 4.1Å; F384-I473 HydrophobicContact CE1-CD1 3.75Å; F384-I473 HydrophobicContact CE2-CB 4.43Å; F384-I473 HydrophobicContact CE2-CG2 4Å; F384-I473 HydrophobicContact CZ-CB 3.95Å; F384-I473 HydrophobicContact CZ-CD1 3.87Å; F384-I473 HydrophobicContact CZ-CG1 4.43Å; F384-I473 HydrophobicContact CZ-CG2 3.88Å; F384-T475 HydrophobicContact CD2-CG2 4Å; F384-T475 HydrophobicContact CE2-CG2 3.67Å
385L97.7Very high96.9Very high27 Ų2738.7 Ų38.714%0.14119%0.185CC..G310 helixtrans-74.1-8.1-179-67.2177.2000113.7T383 N387 Q389 R438 L439 H440 L442 I473T383-L385 VanDerWaalsContact C-N 3.32Å; T383-L385 PolarHBondContact O-N 3.34Å; L385-N387 VanDerWaalsContact C-N 3.27Å; L385-Q389 PolarHBondContact O-NE2 3Å; L385-R438 PolarHBondContact O-NH2 2.84Å; L385-L439 HydrophobicContact CD2-CD2 4.12Å; L385-L439 HydrophobicContact CD2-CG 4.25Å; L385-H440 VanDerWaalsContact CD1-O 3.22Å; L385-H440 WeakPolarHBondContact CD1-O 3.35Å; L385-L442 HydrophobicContact CD1-CG 4.33Å; L385-L442 HydrophobicContact CD2-CD2 4.47Å; L385-L442 HydrophobicContact CD2-CG 4.47Å; L385-I473 HydrophobicContact CD2-CD1 3.67Å
386Q97.6Very high96.7Very high36 Ų3642.6 Ų42.617%0.16820%0.202CC..G310 helixtrans-70.9-26172.3-56.6175.55.700111.2N372 R373 T383 F384 R438N372-Q386 HydrophobicContact CB-CB 4.46Å; N372-Q386 PolarHBondContact ND2-OE1 3.33Å; N372-Q386 CarbonylContact O-C 3.47Å; R373-Q386 WeakPolarHBondContact CA-O 3.46Å; R373-Q386 WeakPolarHBondContact CD-O 3.29Å; T383-Q386 WeakPolarHBondContact O-CA 3.38Å; T383-Q386 WeakPolarHBondContact O-CB 3.37Å; T383-Q386 VanDerWaalsContact O-CG 3.29Å; T383-Q386 WeakPolarHBondContact O-CG 3.41Å; T383-Q386 PolarHBondContact O-N 3.01Å; F384-Q386 PolarHBondContact O-N 3.49Å; Q386-R438 PolarHBondContact O-NH2 3.39Å
387N98.6Very high96.3Very high0 Ų048 Ų480%024%0.235CC..SBendtrans-52.3159.9176.7-71.2-66.5000112.8R373 G375 G376 F384 L385 Q389 R438 I473 T475R373-N387 PolarHBondContact O-OD1 3.16Å; G375-N387 WeakPolarHBondContact CA-ND2 3.44Å; G375-N387 PolarHBondContact N-OD1 3.13Å; G376-N387 PolarHBondContact N-ND2 3.46Å; G376-N387 PolarHBondContact O-ND2 3.48Å; F384-N387 WeakPolarHBondContact O-CB 3.39Å; F384-N387 PolarHBondContact O-N 3.02Å; F384-N387 PolarHBondContact O-ND2 3.39Å; L385-N387 VanDerWaalsContact C-N 3.27Å; N387-Q389 WeakPolarHBondContact O-CG 3.35Å; N387-Q389 PolarHBondContact O-N 2.97Å; N387-R438 PolarHBondContact O-NH1 2.94Å; N387-R438 PolarHBondContact O-NH2 2.91Å; N387-I473 HydrophobicContact CB-CG2 3.65Å; N387-T475 HydrophobicContact CB-CG2 4.12Å; N387-T475 VanDerWaalsContact ND2-CG2 3.34Å; N387-T475 WeakPolarHBondContact ND2-CG2 3.47Å
388P98.6Very high96.1Very high2 Ų253 Ų531%0.01326%0.258CS..  trans-53.4142.7170.4-26.537.8000110.6A362 R373 Y390 P474 F485A362-P388 WeakPolarHBondContact O-CG 3.44Å; R373-P388 HydrophobicContact CB-CG 4.14Å; R373-P388 WeakPolarHBondContact O-CD 3.28Å; P388-Y390 HydrophobicContact CB-CE2 3.73Å; P388-P474 WeakPolarHBondContact O-CD 3.23Å; P388-F485 HydrophobicContact CB-CZ 3.97Å; P388-F485 HydrophobicContact CG-CE1 3.97Å; P388-F485 HydrophobicContact CG-CZ 3.9Å
389Q98.6Very high96Very high0 Ų050.9 Ų50.90%025%0.249CC..  trans-127.1126.7-177.7-61.4-179.312.100108.5L385 N387 L439 V471 I473 E499 L500L385-Q389 PolarHBondContact O-NE2 3Å; N387-Q389 WeakPolarHBondContact O-CG 3.35Å; N387-Q389 PolarHBondContact O-N 2.97Å; Q389-L439 PolarHBondContact NE2-O 2.86Å; Q389-V471 HydrophobicContact CB-CG1 3.98Å; Q389-V471 HydrophobicContact CG-CG1 4.44Å; Q389-I473 HydrophobicContact CG-CD1 4.26Å; Q389-I473 HydrophobicContact CG-CG1 4.22Å; Q389-E499 CarbonylContact O-C 3.57Å; Q389-E499 WeakPolarHBondContact O-CA 3.41Å; Q389-L500 HydrophobicContact CB-CB 4.19Å; Q389-L500 HydrophobicContact CB-CD1 4.31Å; Q389-L500 PolarHBondContact O-N 3.13Å
390Y98.7Very high95.9Very high0 Ų049.5 Ų49.50%024%0.237CC..EExtended strand (participates in β ladder)trans-117.3125-178.7-63.7-91.6000110.1M359 G361 P388 V471 L472 P474 F485 L487 R498 E499M359-Y390 HydrophobicContact CB-CD1 4.12Å; M359-Y390 HydrophobicContact CB-CE1 3.62Å; M359-Y390 HydrophobicContact CE-CD1 4.25Å; M359-Y390 HydrophobicContact CE-CE1 3.97Å; M359-Y390 HydrophobicContact CG-CD1 3.92Å; M359-Y390 HydrophobicContact CG-CE1 3.91Å; G361-Y390 WeakPolarHBondContact CA-OH 3.38Å; P388-Y390 HydrophobicContact CB-CE2 3.73Å; Y390-V471 CarbonylContact O-C 3.46Å; Y390-V471 WeakPolarHBondContact O-CA 3.45Å; Y390-L472 PolarHBondContact N-O 3.04Å; Y390-L472 PolarHBondContact O-N 3.22Å; Y390-P474 HydrophobicContact CD2-CG 4.01Å; Y390-P474 HydrophobicContact CE2-CG 3.74Å; Y390-F485 AromaticContact CE2-CE2 3.81Å; Y390-F485 HydrophobicContact CE2-CE2 3.81Å; Y390-F485 AromaticContact CE2-CZ 3.85Å; Y390-F485 HydrophobicContact CE2-CZ 3.85Å; Y390-F485 AromaticContact CZ-CE2 3.97Å; Y390-F485 WeakPolarHBondContact OH-CE2 3.39Å; Y390-F485 WeakPolarHBondContact OH-CZ 3.19Å; Y390-L487 HydrophobicContact CD1-CD2 4.18Å; Y390-L487 HydrophobicContact CD2-CD2 3.61Å; Y390-L487 HydrophobicContact CE2-CD2 4.11Å; Y390-L487 HydrophobicContact CG-CD2 3.64Å; Y390-R498 CarbonylContact C-O 3.52Å; Y390-R498 WeakPolarHBondContact CA-O 3.4Å; Y390-E499 HydrophobicContact CD1-CB 3.98Å; Y390-E499 HydrophobicContact CD1-CG 4.35Å; Y390-E499 HydrophobicContact CE1-CB 3.81Å; Y390-E499 HydrophobicContact CE1-CG 4Å
391I98.5Very high95.8Very high4 Ų447.3 Ų47.32%0.02123%0.226CC..EExtended strand (participates in β ladder)trans-100.2139.3-179.6-159.1167.6000110.6R435 R469 Y470 V471 L497 R498 L500I391-R435 HydrophobicContact CD1-CB 4.25Å; I391-R435 HydrophobicContact CD1-CG 4.28Å; I391-R435 WeakPolarHBondContact CD1-O 3.07Å; I391-R469 HydrophobicContact CD1-CG 3.8Å; I391-R469 HydrophobicContact CG1-CG 3.81Å; I391-Y470 CarbonylContact C-O 3.53Å; I391-Y470 VanDerWaalsContact CA-O 3.29Å; I391-Y470 WeakPolarHBondContact CA-O 3.38Å; I391-Y470 WeakPolarHBondContact CG1-O 3.19Å; I391-V471 HydrophobicContact CB-CG2 4.45Å; I391-V471 HydrophobicContact CD1-CG2 4.4Å; I391-V471 HydrophobicContact CG1-CG2 4.14Å; I391-L497 VanDerWaalsContact O-CA 3.3Å; I391-L497 WeakPolarHBondContact O-CA 3.39Å; I391-R498 HydrophobicContact CG2-CG 3.56Å; I391-R498 PolarHBondContact N-O 3.27Å; I391-R498 PolarHBondContact O-N 3.49Å; I391-L500 HydrophobicContact CB-CD1 4.06Å; I391-L500 HydrophobicContact CB-CD2 4.03Å; I391-L500 HydrophobicContact CB-CG 3.93Å; I391-L500 HydrophobicContact CD1-CD1 4.27Å; I391-L500 HydrophobicContact CD1-CD2 4.15Å; I391-L500 HydrophobicContact CG2-CD2 3.76Å; I391-L500 HydrophobicContact CG2-CG 4.08Å
392F98.3Very high95.9Very high1 Ų137.7 Ų37.70%0.00419%0.19CC..EExtended strand (participates in β ladder)trans-148.8160.1174.672.2-81.8000111.6V394 V401 I428 L465 Y470 L472 L489 L497F392-V394 HydrophobicContact CD2-CG2 4.45Å; F392-V394 HydrophobicContact CE2-CG2 3.99Å; F392-V401 HydrophobicContact CE2-CG1 4.22Å; F392-V401 HydrophobicContact CE2-CG2 4.49Å; F392-V401 HydrophobicContact CZ-CG1 4.44Å; F392-I428 HydrophobicContact CE1-CG2 4.25Å; F392-I428 HydrophobicContact CZ-CG2 4.2Å; F392-L465 HydrophobicContact CE2-CD1 4.2Å; F392-L465 HydrophobicContact CZ-CD1 3.97Å; F392-Y470 VanDerWaalsContact CE1-CB 3.43Å; F392-Y470 HydrophobicContact CE1-CG 4.39Å; F392-Y470 HydrophobicContact CE2-CD2 4.05Å; F392-Y470 HydrophobicContact CE2-CG 4.25Å; F392-Y470 VanDerWaalsContact CZ-CB 3.48Å; F392-Y470 HydrophobicContact CZ-CD2 4.22Å; F392-Y470 AromaticContact CZ-CG 3.95Å; F392-Y470 HydrophobicContact CZ-CG 3.95Å; F392-Y470 PolarHBondContact N-O 2.75Å; F392-Y470 PolarHBondContact O-N 2.89Å; F392-L472 HydrophobicContact CD1-CB 4.46Å; F392-L472 HydrophobicContact CE1-CB 4.13Å; F392-L472 HydrophobicContact CE1-CD1 4.48Å; F392-L489 HydrophobicContact CB-CD2 3.76Å; F392-L489 HydrophobicContact CD1-CD2 4.29Å; F392-L489 HydrophobicContact CD2-CD2 3.78Å; F392-L489 HydrophobicContact CE2-CD2 4.44Å; F392-L489 HydrophobicContact CG-CD2 3.68Å; F392-L497 HydrophobicContact CB-CB 4.38Å; F392-L497 HydrophobicContact CB-CD1 3.99Å
393D96.6Very high96.1Very high22 Ų2230.5 Ų30.512%0.11815%0.152CC..EExtended strand (participates in β ladder)trans-114.5134.4-177.4-63.3-28.5000110.4R469 S495D393-R469 IonicContact OD1-CZ 3.74Å; D393-R469 IonicContact OD1-NE 3.66Å; D393-R469 PolarHBondContact OD1-NE 3.48Å; D393-R469 IonicContact OD1-NH2 2.73Å; D393-R469 PolarHBondContact OD1-NH2 2.72Å; D393-R469 VanDerWaalsContact OD1-NH2 3.12Å; D393-R469 IonicContact OD2-NH2 3.82Å; D393-R469 PolarHBondContact OD2-NH2 3.28Å; D393-R469 VanDerWaalsContact OD2-NH2 3.13Å; D393-S495 PolarHBondContact N-O 3.22Å; D393-S495 WeakPolarHBondContact O-CA 3.28Å
394V95.9Very high96.1Very high4 Ų428.6 Ų28.62%0.02414%0.14CC..EExtended strand (participates in β ladder)trans-100116.4163.4177.60000107.7F392 D399 V401 L465 K466 Q467 G468 Y470F392-V394 HydrophobicContact CD2-CG2 4.45Å; F392-V394 HydrophobicContact CE2-CG2 3.99Å; V394-D399 HydrophobicContact CG1-CB 3.56Å; V394-V401 HydrophobicContact CG2-CG2 4.06Å; V394-L465 HydrophobicContact CG2-CB 4.11Å; V394-L465 HydrophobicContact CG2-CD1 4.46Å; V394-K466 WeakPolarHBondContact CB-O 3.41Å; V394-K466 WeakPolarHBondContact CG1-O 3.19Å; V394-Q467 WeakPolarHBondContact O-CA 3.39Å; V394-Q467 WeakPolarHBondContact O-CG 3.44Å; V394-G468 PolarHBondContact N-O 3.36Å; V394-G468 PolarHBondContact O-N 2.94Å; V394-Y470 HydrophobicContact CB-CD2 4.43Å; V394-Y470 HydrophobicContact CB-CE2 3.89Å; V394-Y470 HydrophobicContact CG2-CD2 3.86Å; V394-Y470 HydrophobicContact CG2-CE2 3.61Å
395K92.5Very high96.1Very high92 Ų9228.4 Ų28.440%0.414%0.139SC..EExtended strand (participates in β ladder)trans-96.5-26.8-172.9-65.1178.5-178.31570114.3Q467 V493 P494K395-Q467 PolarHBondContact O-NE2 2.98Å; K395-V493 HydrophobicContact CB-CG2 4.12Å; K395-P494 VanDerWaalsContact CE-O 3.3Å; K395-P494 WeakPolarHBondContact CE-O 3.45Å; K395-P494 PolarHBondContact NZ-O 3.25Å
396K92.8Very high96Very high81 Ų8127.2 Ų27.235%0.35213%0.133SC..EExtended strand (participates in β ladder)trans-73.3159.5173.4-63.4-174.9-179.7-174.50109.4E398 D399 Q467 D492 V493K396-E398 VanDerWaalsContact CB-O 3.29Å; K396-E398 WeakPolarHBondContact CB-O 3.17Å; K396-E398 PolarHBondContact O-N 3.37Å; K396-D399 HydrophobicContact CB-CB 4.33Å; K396-Q467 VanDerWaalsContact O-CA 3.31Å; K396-Q467 WeakPolarHBondContact O-CA 3.48Å; K396-Q467 WeakPolarHBondContact O-CB 3.41Å; K396-Q467 PolarHBondContact O-N 3.33Å; K396-D492 HydrophobicContact CD-CB 4.3Å; K396-D492 IonicContact NZ-OD2 3.25Å; K396-D492 PolarHBondContact NZ-OD2 2.66Å; K396-V493 HydrophobicContact CG-CG2 4.33Å
397T91.4Very high96Very high115 Ų11525.5 Ų25.571%0.70613%0.125SC*.EExtended strand (participates in β ladder)trans-52.5-43.4172.646.30000111.3K466 Q467T397-K466 CarbonylContact O-C 3.58Å; T397-K466 WeakPolarHBondContact O-CA 3.49Å; T397-Q467 PolarHBondContact O-N 2.78Å
398E93.3Very high95.7Very high108 Ų10827.5 Ų27.551%0.50513%0.134SC..EExtended strand (participates in β ladder)trans-140.1141.4165.9-63.2-171.3156.100109.5K396 V464 L465 K466K396-E398 VanDerWaalsContact CB-O 3.29Å; K396-E398 WeakPolarHBondContact CB-O 3.17Å; K396-E398 PolarHBondContact O-N 3.37Å; E398-V464 HydrophobicContact CB-CG1 3.99Å; E398-L465 CarbonylContact C-O 3.44Å; E398-L465 WeakPolarHBondContact CA-O 3.36Å; E398-K466 HydrophobicContact CG-CG 4.25Å
399D93.8Very high95.4Very high4 Ų429.3 Ų29.32%0.02114%0.144CC..EExtended strand (participates in β ladder)trans-135.4147.4174.4-158.51.7000111V394 K396 V464 L465 D492V394-D399 HydrophobicContact CG1-CB 3.56Å; K396-D399 HydrophobicContact CB-CB 4.33Å; D399-V464 WeakPolarHBondContact O-CA 3.49Å; D399-L465 PolarHBondContact N-O 3.07Å; D399-L465 PolarHBondContact O-N 2.82Å; D399-D492 VanDerWaalsContact OD1-CB 3.24Å; D399-D492 WeakPolarHBondContact OD1-CB 3.47Å; D399-D492 PolarHBondContact OD2-N 3.32Å
400K92.8Very high95Very high88 Ų8831.7 Ų31.738%0.38315%0.153SC..EExtended strand (participates in β ladder)trans-83.9120.1172-174.6175-65.9-172.50107.7W354 L402 K462W354-K400 HydrophobicContact CH2-CB 4.17Å; W354-K400 HydrophobicContact CH2-CD 4.08Å; W354-K400 HydrophobicContact CH2-CG 4.05Å; W354-K400 VanDerWaalsContact CZ3-O 3.28Å; W354-K400 WeakPolarHBondContact CZ3-O 3Å; K400-L402 HydrophobicContact CD-CD2 4.36Å; K400-L402 HydrophobicContact CG-CD2 4.15Å; K400-K462 HydrophobicContact CD-CG 4.38Å; K400-K462 HydrophobicContact CG-CG 4.48Å
401V94.9Very high94.7Very high2 Ų233 Ų331%0.01216%0.158CC..EExtended strand (participates in β ladder)trans-109.2127.8179.7-1760000109F392 V394 V403 R463 L465 L489 T491F392-V401 HydrophobicContact CE2-CG1 4.22Å; F392-V401 HydrophobicContact CE2-CG2 4.49Å; F392-V401 HydrophobicContact CZ-CG1 4.44Å; V394-V401 HydrophobicContact CG2-CG2 4.06Å; V401-V403 HydrophobicContact CG1-CG2 4.11Å; V401-R463 PolarHBondContact N-O 3.2Å; V401-R463 PolarHBondContact O-N 3.39Å; V401-L465 HydrophobicContact CB-CD1 4.25Å; V401-L465 HydrophobicContact CB-CG 4.49Å; V401-L465 HydrophobicContact CG2-CB 4.22Å; V401-L465 HydrophobicContact CG2-CD1 3.91Å; V401-L465 HydrophobicContact CG2-CG 4.11Å; V401-L489 HydrophobicContact CG1-CD1 3.41Å; V401-L489 VanDerWaalsContact CG1-CD1 3.41Å; V401-T491 HydrophobicContact CG1-CG2 4.3Å; V401-T491 HydrophobicContact CG2-CG2 4.15Å
402L95.3Very high94.2Very high9 Ų938.3 Ų38.35%0.04718%0.178CC..EExtended strand (participates in β ladder)trans-110.7129.9171.5-40.8177.9000108.8W354 K400 F460 L461 K462 L489 F490W354-L402 HydrophobicContact CE3-CD1 4.45Å; W354-L402 HydrophobicContact CH2-CD1 3.8Å; W354-L402 HydrophobicContact CH2-CD2 4.22Å; W354-L402 HydrophobicContact CH2-CG 3.82Å; W354-L402 HydrophobicContact CZ2-CD1 3.98Å; W354-L402 HydrophobicContact CZ2-CG 4.49Å; W354-L402 HydrophobicContact CZ3-CD1 4.05Å; W354-L402 HydrophobicContact CZ3-CG 3.88Å; K400-L402 HydrophobicContact CD-CD2 4.36Å; K400-L402 HydrophobicContact CG-CD2 4.15Å; L402-F460 HydrophobicContact CB-CE2 3.86Å; L402-F460 HydrophobicContact CB-CZ 4.05Å; L402-F460 HydrophobicContact CD1-CZ 4.45Å; L402-F460 HydrophobicContact CD2-CZ 4.04Å; L402-F460 HydrophobicContact CG-CZ 4.41Å; L402-L461 WeakPolarHBondContact CA-O 3.48Å; L402-K462 HydrophobicContact CD2-CB 3.84Å; L402-K462 HydrophobicContact CD2-CD 4.09Å; L402-K462 HydrophobicContact CD2-CG 3.59Å; L402-L489 WeakPolarHBondContact O-CA 3.32Å; L402-F490 HydrophobicContact CB-CB 4.03Å; L402-F490 HydrophobicContact CB-CD2 4.18Å; L402-F490 HydrophobicContact CD1-CB 4.3Å; L402-F490 HydrophobicContact CG-CB 4.31Å; L402-F490 PolarHBondContact N-O 2.79Å; L402-F490 PolarHBondContact O-N 3.41Å
403V97Very high93.8Very high2 Ų242 Ų421%0.01219%0.192CC..EExtended strand (participates in β ladder)trans-122.2131.1177.6-178.80000108.4V401 F426 I428 F460 L461 L472 L487 R488 L489V401-V403 HydrophobicContact CG1-CG2 4.11Å; V403-F426 HydrophobicContact CB-CE1 4.37Å; V403-F426 HydrophobicContact CB-CE2 3.78Å; V403-F426 HydrophobicContact CB-CZ 3.54Å; V403-F426 HydrophobicContact CG1-CD1 4.32Å; V403-F426 HydrophobicContact CG1-CD2 4.15Å; V403-F426 HydrophobicContact CG1-CE1 3.73Å; V403-F426 HydrophobicContact CG1-CE2 3.54Å; V403-F426 HydrophobicContact CG1-CZ 3.3Å; V403-F426 HydrophobicContact CG2-CE2 4.25Å; V403-F426 HydrophobicContact CG2-CZ 4.48Å; V403-I428 HydrophobicContact CG2-CD1 4.12Å; V403-F460 CarbonylContact O-C 3.53Å; V403-F460 WeakPolarHBondContact O-CA 3.5Å; V403-F460 WeakPolarHBondContact O-CD2 3.26Å; V403-L461 PolarHBondContact N-O 3.43Å; V403-L461 PolarHBondContact O-N 3.15Å; V403-L472 HydrophobicContact CB-CD1 4.46Å; V403-L472 HydrophobicContact CG1-CD1 3.67Å; V403-L472 HydrophobicContact CG2-CD1 3.89Å; V403-L487 HydrophobicContact CG1-CD1 3.76Å; V403-R488 WeakPolarHBondContact CA-O 3.41Å; V403-L489 HydrophobicContact CG2-CD1 3.75Å
404S96.9Very high93.5Very high0 Ų043.2 Ų43.20%020%0.196CC..EExtended strand (participates in β ladder)trans-125.2119.7169.51710000109.1T458 V459 R488S404-T458 WeakPolarHBondContact OG-CG2 3.27Å; S404-V459 WeakPolarHBondContact CA-O 3.21Å; S404-R488 PolarHBondContact N-O 2.55Å; S404-R488 PolarHBondContact O-N 3.36Å; S404-R488 PolarHBondContact OG-NH2 3.38Å
405L97.8Very high93.1Very high0 Ų049.2 Ų49.20%022%0.222CC..EExtended strand (participates in β ladder)trans-105.3125.7170.7177.465.2000107.8W363 I424 G425 F426 T458 V459 P474 F485 L487W363-L405 HydrophobicContact CH2-CD2 4.4Å; W363-L405 HydrophobicContact CZ2-CD2 4.29Å; L405-I424 HydrophobicContact CD2-CB 4.3Å; L405-I424 HydrophobicContact CD2-CD1 4.38Å; L405-I424 HydrophobicContact CG-CD1 4.23Å; L405-G425 WeakPolarHBondContact CD2-O 3.28Å; L405-F426 HydrophobicContact CB-CD1 3.78Å; L405-F426 HydrophobicContact CB-CE1 4.03Å; L405-F426 HydrophobicContact CD2-CB 4.47Å; L405-F426 HydrophobicContact CD2-CD1 4.02Å; L405-T458 CarbonylContact O-C 3.44Å; L405-T458 WeakPolarHBondContact O-CA 3.24Å; L405-V459 PolarHBondContact N-O 3.3Å; L405-V459 PolarHBondContact O-N 2.96Å; L405-P474 HydrophobicContact CD1-CB 3.63Å; L405-P474 HydrophobicContact CD2-CB 3.8Å; L405-P474 HydrophobicContact CG-CB 4.35Å; L405-F485 HydrophobicContact CD1-CB 3.85Å; L405-F485 HydrophobicContact CD1-CD2 3.54Å; L405-F485 HydrophobicContact CD1-CE2 4.33Å; L405-F485 HydrophobicContact CD1-CG 3.85Å; L405-L487 HydrophobicContact CD1-CD1 4.5Å
406Q97.1Very high93.1Very high2 Ų249.6 Ų49.61%0.00923%0.225CC..EExtended strand (participates in β ladder)trans-131134.8-178.9172.1177.7-1.700109.9F128 R457 T458 F485 I486F128-Q406 HydrophobicContact CD2-CG 4.4Å; F128-Q406 WeakPolarHBondContact CE2-O 3.19Å; Q406-R457 VanDerWaalsContact CA-O 3.31Å; Q406-R457 WeakPolarHBondContact CA-O 3.47Å; Q406-R457 HydrophobicContact CG-CG 4.49Å; Q406-T458 HydrophobicContact CB-CG2 4.33Å; Q406-F485 CarbonylContact O-C 3.58Å; Q406-F485 WeakPolarHBondContact O-CA 3.33Å; Q406-F485 VanDerWaalsContact O-CB 3.3Å; Q406-F485 WeakPolarHBondContact O-CB 3.39Å; Q406-I486 HydrophobicContact CB-CD1 4.25Å; Q406-I486 HydrophobicContact CB-CG1 3.72Å; Q406-I486 HydrophobicContact CG-CD1 4.41Å; Q406-I486 HydrophobicContact CG-CG1 4.23Å; Q406-I486 PolarHBondContact N-O 2.9Å; Q406-I486 PolarHBondContact O-N 3.24Å
407Q95.7Very high92.8Very high0 Ų049 Ų490%024%0.242CC..EExtended strand (participates in β ladder)trans-91.3161.4172.563.8-173-57.200111.3I422 I424 T456 R457Q407-I422 PolarHBondContact NE2-O 3.37Å; Q407-I424 HydrophobicContact CB-CD1 4.14Å; Q407-I424 HydrophobicContact CG-CD1 4.16Å; Q407-T456 PolarHBondContact NE2-O 3.45Å; Q407-R457 HydrophobicContact CG-CG 4.32Å; Q407-R457 PolarHBondContact N-O 2.87Å
408E93.3Very high92.6Very high41 Ų4150 Ų5019%0.19223%0.233CC..PPolyproline II helixtrans-58.1148.9175.4-76.8-179.5126.200111.1F128 R410 K484F128-E408 HydrophobicContact CD1-CG 3.89Å; F128-E408 HydrophobicContact CD2-CG 4.13Å; F128-E408 HydrophobicContact CE1-CG 3.54Å; F128-E408 HydrophobicContact CE2-CB 4.36Å; F128-E408 HydrophobicContact CE2-CG 3.82Å; F128-E408 VanDerWaalsContact CE2-N 3.28Å; F128-E408 HydrophobicContact CG-CG 4.15Å; F128-E408 HydrophobicContact CZ-CB 4.43Å; F128-E408 HydrophobicContact CZ-CG 3.46Å; F128-E408 VanDerWaalsContact CZ-CG 3.46Å; E408-R410 WeakPolarHBondContact O-CG 3.34Å; E408-R410 PolarHBondContact O-N 2.88Å; E408-K484 HydrophobicContact CG-CB 3.98Å; E408-K484 IonicContact OE1-NZ 3.31Å
409D91.8Very high92.3Very high41 Ų4145.4 Ų45.422%0.21922%0.215CC..PPolyproline II helixtrans-67.7128172.1-158.9-39.4000110.6R411 R457D409-R411 WeakPolarHBondContact OD1-CB 3.37Å; D409-R411 WeakPolarHBondContact OD1-CG 3.49Å; D409-R411 PolarHBondContact OD1-N 3.21Å; D409-R411 IonicContact OD1-NE 3.13Å; D409-R411 PolarHBondContact OD1-NE 2.79Å; D409-R411 VanDerWaalsContact OD1-NE 3.17Å; D409-R411 IonicContact OD2-CZ 3.37Å; D409-R411 VanDerWaalsContact OD2-CZ 3.25Å; D409-R411 IonicContact OD2-NE 3.12Å; D409-R411 PolarHBondContact OD2-NE 3.3Å; D409-R411 IonicContact OD2-NH2 2.87Å; D409-R411 PolarHBondContact OD2-NH2 2.76Å; D409-R457 IonicContact OD2-CZ 2.72Å; D409-R457 IonicContact OD2-NH1 2.68Å; D409-R457 PolarHBondContact OD2-NH1 3.11Å
410R91.4Very high92.1Very high50 Ų5053 Ų5319%0.18925%0.25CS..  trans-106.4-4.2-175.7-58.5178.465.293.14.7112.6E408 R412 Y413 R418 G419 E420E408-R410 WeakPolarHBondContact O-CG 3.34Å; E408-R410 PolarHBondContact O-N 2.88Å; R410-R412 PolarHBondContact O-N 3.06Å; R410-R412 VanDerWaalsContact O-N 3.12Å; R410-Y413 HydrophobicContact CB-CD2 4.43Å; R410-Y413 WeakPolarHBondContact O-CA 3.42Å; R410-Y413 WeakPolarHBondContact O-CB 3.35Å; R410-Y413 PolarHBondContact O-N 3.37Å; R410-R418 PolarHBondContact NE-O 3.2Å; R410-R418 PolarHBondContact NH2-O 2.78Å; R410-R418 VanDerWaalsContact NH2-O 3.16Å; R410-G419 VanDerWaalsContact O-CA 3.29Å; R410-G419 WeakPolarHBondContact O-CA 3.34Å; R410-E420 WeakPolarHBondContact CD-O 3.31Å; R410-E420 PolarHBondContact NE-O 3.46Å
411R91.1Very high92.1Very high26 Ų2650.5 Ų50.510%0.09824%0.244CC..G310 helixtrans-54.8-36.1-175.9-74178.6-70.3158.7-10113.7W82 Y167 A171 D188 D409 Y413 K414W82-R411 VanDerWaalsContact CH2-NH1 3.34Å; Y167-R411 VanDerWaalsContact CZ-NH2 3.35Å; Y167-R411 PolarHBondContact OH-NH1 2.81Å; Y167-R411 PolarHBondContact OH-NH2 2.87Å; A171-R411 HydrophobicContact CB-CB 4.25Å; A171-R411 CarbonylContact O-C 3.52Å; D188-R411 IonicContact OD2-NH2 3Å; D188-R411 PolarHBondContact OD2-NH2 3.49Å; D409-R411 WeakPolarHBondContact OD1-CB 3.37Å; D409-R411 WeakPolarHBondContact OD1-CG 3.49Å; D409-R411 PolarHBondContact OD1-N 3.21Å; D409-R411 IonicContact OD1-NE 3.13Å; D409-R411 PolarHBondContact OD1-NE 2.79Å; D409-R411 VanDerWaalsContact OD1-NE 3.17Å; D409-R411 IonicContact OD2-CZ 3.37Å; D409-R411 VanDerWaalsContact OD2-CZ 3.25Å; D409-R411 IonicContact OD2-NE 3.12Å; D409-R411 PolarHBondContact OD2-NE 3.3Å; D409-R411 IonicContact OD2-NH2 2.87Å; D409-R411 PolarHBondContact OD2-NH2 2.76Å; R411-Y413 PolarHBondContact O-N 2.93Å; R411-K414 VanDerWaalsContact O-CB 3.29Å; R411-K414 WeakPolarHBondContact O-CB 3.46Å; R411-K414 WeakPolarHBondContact O-CG 3.35Å; R411-K414 PolarHBondContact O-N 3.43Å
412R88.3Confident92.1Very high117 Ų11751.7 Ų51.744%0.44225%0.25SC..G310 helixtrans-54.8-22.6172.462178.1154.9176.7-3.2115.3A171 R410A171-R412 WeakPolarHBondContact O-CA 3.45Å; A171-R412 PolarHBondContact O-N 3.1Å; R410-R412 PolarHBondContact O-N 3.06Å; R410-R412 VanDerWaalsContact O-N 3.12Å
413Y90.4Very high92.2Very high78 Ų7853.4 Ų53.431%0.30626%0.262SS..G310 helixtrans-102.19179.5-49.8-60.5000112.7R410 R411 K415 E416 G417 R418 G419R410-Y413 HydrophobicContact CB-CD2 4.43Å; R410-Y413 WeakPolarHBondContact O-CA 3.42Å; R410-Y413 WeakPolarHBondContact O-CB 3.35Å; R410-Y413 PolarHBondContact O-N 3.37Å; R411-Y413 PolarHBondContact O-N 2.93Å; Y413-K415 PolarHBondContact O-N 2.94Å; Y413-E416 WeakPolarHBondContact CB-OE2 3.33Å; Y413-E416 WeakPolarHBondContact CD1-OE2 3.33Å; Y413-E416 PolarHBondContact O-N 2.88Å; Y413-E416 VanDerWaalsContact O-N 3.08Å; Y413-G417 PolarHBondContact O-N 2.79Å; Y413-R418 PolarHBondContact O-N 3.5Å; Y413-G419 PolarHBondContact O-N 2.97Å
414K89.8Confident92.2Very high48 Ų4853.3 Ų53.321%0.20926%0.261CS..G310 helixtrans-57.5-39174.9-84.1-176170.9179.10111.3Y41 A176 D178 G179 R411 E416 G417Y41-K414 HydrophobicContact CE2-CB 4.44Å; Y41-K414 WeakPolarHBondContact OH-CB 3.39Å; A176-K414 HydrophobicContact CB-CD 4.42Å; A176-K414 PolarHBondContact O-NZ 3.22Å; D178-K414 PolarHBondContact O-NZ 2.85Å; G179-K414 PolarHBondContact O-NZ 2.83Å; G179-K414 VanDerWaalsContact O-NZ 3.16Å; R411-K414 VanDerWaalsContact O-CB 3.29Å; R411-K414 WeakPolarHBondContact O-CB 3.46Å; R411-K414 WeakPolarHBondContact O-CG 3.35Å; R411-K414 PolarHBondContact O-N 3.43Å; K414-E416 PolarHBondContact O-N 3.46Å; K414-E416 VanDerWaalsContact O-N 3.16Å; K414-G417 PolarHBondContact O-N 3.11Å
415K88.4Confident92.3Very high129 Ų12953.3 Ų53.356%0.56126%0.261SS*.G310 helixtrans-55.7-30.8174.7-179.9171.2-177.4177.40113.5Y41 Y413Y41-K415 HydrophobicContact CD1-CB 4.23Å; Y41-K415 HydrophobicContact CD2-CB 4Å; Y41-K415 HydrophobicContact CD2-CG 4.28Å; Y41-K415 HydrophobicContact CG-CB 3.86Å; Y41-K415 HydrophobicContact CG-CD 4.47Å; Y41-K415 HydrophobicContact CG-CG 4.01Å; Y413-K415 PolarHBondContact O-N 2.94Å
416E90.9Very high92.3Very high100 Ų10053.3 Ų53.347%0.46726%0.261SS..G310 helixtrans-9811.3178.1-50.7115.2-150.500113.2Y413 K414 R418Y413-E416 WeakPolarHBondContact CB-OE2 3.33Å; Y413-E416 WeakPolarHBondContact CD1-OE2 3.33Å; Y413-E416 PolarHBondContact O-N 2.88Å; Y413-E416 VanDerWaalsContact O-N 3.08Å; K414-E416 PolarHBondContact O-N 3.46Å; K414-E416 VanDerWaalsContact O-N 3.16Å; E416-R418 VanDerWaalsContact C-N 3.26Å; E416-R418 PolarHBondContact O-N 3.47Å; E416-R418 IonicContact OE2-CZ 3.47Å; E416-R418 IonicContact OE2-NE 2.94Å; E416-R418 IonicContact OE2-NH2 3.86Å; E416-R418 PolarHBondContact OE2-NH2 2.71Å
417G87.6Confident92.3Very high69 Ų6953.3 Ų53.371%0.71126%0.261SS*.THydrogen-bonded Turntrans70.117.7-177.400000114.4Y413 K414Y413-G417 PolarHBondContact O-N 2.79Å; K414-G417 PolarHBondContact O-N 3.11Å
418R87.6Confident92.5Very high135 Ų13553.4 Ų53.451%0.50926%0.261SS..  trans-114.416-178-62.8-176.9-60165.23113.4R410 Y413 E416R410-R418 PolarHBondContact NE-O 3.2Å; R410-R418 PolarHBondContact NH2-O 2.78Å; R410-R418 VanDerWaalsContact NH2-O 3.16Å; Y413-R418 PolarHBondContact O-N 3.5Å; E416-R418 VanDerWaalsContact C-N 3.26Å; E416-R418 PolarHBondContact O-N 3.47Å; E416-R418 IonicContact OE2-CZ 3.47Å; E416-R418 IonicContact OE2-NE 2.94Å; E416-R418 IonicContact OE2-NH2 3.86Å; E416-R418 PolarHBondContact OE2-NH2 2.71Å
419G86.6Confident92.7Very high12 Ų1251.6 Ų51.612%0.12425%0.253CS..  trans-80.8-10.9-173.100000116R410 Y413R410-G419 VanDerWaalsContact O-CA 3.29Å; R410-G419 WeakPolarHBondContact O-CA 3.34Å; Y413-G419 PolarHBondContact O-N 2.97Å
420E89.4Confident92.9Very high164 Ų16450.3 Ų50.377%0.76625%0.246SC*.SBendtrans-71.5146.8177.3-64.3-172.1168.300112.1R410R410-E420 WeakPolarHBondContact CD-O 3.31Å; R410-E420 PolarHBondContact NE-O 3.46Å
421S93.1Very high93.2Very high36 Ų3648 Ų4825%0.25224%0.237SC..PPolyproline II helixtrans-72.5140.7173.3-73.60000110.6N455 R457S421-N455 WeakPolarHBondContact CB-O 3.27Å; S421-R457 PolarHBondContact OG-N 2.79Å
422I94.8Very high93.5Very high26 Ų2646.8 Ų46.813%0.13323%0.232CC..PPolyproline II helixtrans-81.7142.6177.4-61.7153.9000108.8Q407 I424 T476 I481 T483Q407-I422 PolarHBondContact NE2-O 3.37Å; I422-I424 PolarHBondContact O-N 3.38Å; I422-I424 VanDerWaalsContact O-N 3.1Å; I422-T476 HydrophobicContact CG2-CG2 4.14Å; I422-I481 HydrophobicContact CD1-CG2 3.73Å; I422-I481 HydrophobicContact CG2-CG2 4.21Å; I422-T483 HydrophobicContact CD1-CG2 3.97Å
423P96.6Very high93.8Very high46 Ų4643.4 Ų43.430%0.29922%0.223SC..  trans-60.5114.7169.8-2232.7000111.1I454 N455 Y477P423-I454 WeakPolarHBondContact CA-O 3.09Å; P423-N455 HydrophobicContact CG-CB 4.22Å; P423-Y477 PolarHBondContact O-N 2.98Å
424I97.9Very high94.1Very high0 Ų041.3 Ų41.30%022%0.217CC..EExtended strand (participates in β ladder)trans-122.315818058.3172.5000110.4W363 L405 Q407 I422 Y453 I454 V459 T475 T476W363-I424 HydrophobicContact CH2-CB 4.25Å; W363-I424 HydrophobicContact CH2-CG2 3.62Å; W363-I424 HydrophobicContact CZ2-CG2 4.46Å; W363-I424 HydrophobicContact CZ3-CG2 4.06Å; L405-I424 HydrophobicContact CD2-CB 4.3Å; L405-I424 HydrophobicContact CD2-CD1 4.38Å; L405-I424 HydrophobicContact CG-CD1 4.23Å; Q407-I424 HydrophobicContact CB-CD1 4.14Å; Q407-I424 HydrophobicContact CG-CD1 4.16Å; I422-I424 PolarHBondContact O-N 3.38Å; I422-I424 VanDerWaalsContact O-N 3.1Å; I424-Y453 WeakPolarHBondContact O-CA 3.25Å; I424-I454 PolarHBondContact N-O 2.9Å; I424-V459 HydrophobicContact CD1-CG2 4.3Å; I424-V459 HydrophobicContact CG1-CG2 3.79Å; I424-T475 WeakPolarHBondContact CA-O 3.06Å; I424-T476 HydrophobicContact CG2-CG2 4.22Å
425G98Very high94.4Very high0 Ų039 Ų390%021%0.207CC..EExtended strand (participates in β ladder)trans-170.4-180176.900000111.4L405 S451 T475L405-G425 WeakPolarHBondContact CD2-O 3.28Å; G425-S451 WeakPolarHBondContact CA-OG 3.44Å; G425-T475 PolarHBondContact N-O 3.43Å; G425-T475 PolarHBondContact O-N 2.97Å; G425-T475 PolarHBondContact O-OG1 3.49Å
426F98.4Very high94.8Very high0 Ų035.6 Ų35.60%020%0.199CC..EExtended strand (participates in β ladder)trans-151.9157.2177.658-93.6000112.6V403 L405 I428 S451 V459 L461 L472 I473 P474V403-F426 HydrophobicContact CB-CE1 4.37Å; V403-F426 HydrophobicContact CB-CE2 3.78Å; V403-F426 HydrophobicContact CB-CZ 3.54Å; V403-F426 HydrophobicContact CG1-CD1 4.32Å; V403-F426 HydrophobicContact CG1-CD2 4.15Å; V403-F426 HydrophobicContact CG1-CE1 3.73Å; V403-F426 HydrophobicContact CG1-CE2 3.54Å; V403-F426 HydrophobicContact CG1-CZ 3.3Å; V403-F426 HydrophobicContact CG2-CE2 4.25Å; V403-F426 HydrophobicContact CG2-CZ 4.48Å; L405-F426 HydrophobicContact CB-CD1 3.78Å; L405-F426 HydrophobicContact CB-CE1 4.03Å; L405-F426 HydrophobicContact CD2-CB 4.47Å; L405-F426 HydrophobicContact CD2-CD1 4.02Å; F426-I428 HydrophobicContact CD2-CG1 4.2Å; F426-I428 HydrophobicContact CE2-CD1 4.25Å; F426-I428 HydrophobicContact CE2-CG1 4.4Å; F426-S451 PolarHBondContact N-OG 3.14Å; F426-S451 PolarHBondContact O-N 3.38Å; F426-V459 HydrophobicContact CE1-CG1 4.02Å; F426-L461 HydrophobicContact CE2-CB 3.86Å; F426-L461 HydrophobicContact CE2-CD2 3.75Å; F426-L461 HydrophobicContact CE2-CG 4.49Å; F426-L461 HydrophobicContact CZ-CB 3.46Å; F426-L461 VanDerWaalsContact CZ-CB 3.46Å; F426-L461 HydrophobicContact CZ-CD2 4.23Å; F426-L472 HydrophobicContact CB-CD2 4.1Å; F426-L472 HydrophobicContact CD2-CD2 4.44Å; F426-L472 HydrophobicContact CD2-CG 4.35Å; F426-L472 HydrophobicContact CG-CD2 4.37Å; F426-I473 VanDerWaalsContact CA-O 3.22Å; F426-I473 WeakPolarHBondContact CA-O 3.44Å; F426-I473 WeakPolarHBondContact CB-O 3.22Å; F426-P474 HydrophobicContact CB-CB 4.44Å
427E98.2Very high95.1Very high2 Ų233.9 Ų33.91%0.00919%0.189CC..EExtended strand (participates in β ladder)trans-118146.4176.6-57-60.6150.300110.1F378 F384 F429 R447 T450 Y453 L472 I473F378-E427 HydrophobicContact CB-CG 4.21Å; F378-E427 HydrophobicContact CD2-CG 4.39Å; F384-E427 HydrophobicContact CE2-CB 4.44Å; F384-E427 HydrophobicContact CE2-CG 3.85Å; F384-E427 HydrophobicContact CZ-CB 3.88Å; F384-E427 HydrophobicContact CZ-CG 3.7Å; E427-F429 HydrophobicContact CB-CD2 4.31Å; E427-F429 HydrophobicContact CB-CE2 3.46Å; E427-F429 VanDerWaalsContact CB-CE2 3.46Å; E427-F429 HydrophobicContact CB-CZ 3.95Å; E427-F429 HydrophobicContact CG-CE2 4.39Å; E427-R447 WeakPolarHBondContact OE2-CD 3.4Å; E427-R447 IonicContact OE2-NH1 3.77Å; E427-T450 PolarHBondContact OE1-OG1 3.44Å; E427-T450 WeakPolarHBondContact OE2-CA 3.3Å; E427-T450 WeakPolarHBondContact OE2-CB 3.22Å; E427-T450 PolarHBondContact OE2-OG1 2.86Å; E427-T450 VanDerWaalsContact OE2-OG1 3.11Å; E427-Y453 PolarHBondContact OE1-OH 3.04Å; E427-L472 WeakPolarHBondContact O-CA 3.33Å; E427-I473 PolarHBondContact N-O 3.21Å; E427-I473 VanDerWaalsContact N-O 3.11Å; E427-I473 PolarHBondContact O-N 3.24Å
428I98.4Very high95.5Very high1 Ų130.8 Ų30.81%0.00516%0.156CC..EExtended strand (participates in β ladder)trans-120.7124.3174.4-51.8-179.2000109.1F392 V403 F426 V448 A449 L461 L465 Y470 V471 L472F392-I428 HydrophobicContact CE1-CG2 4.25Å; F392-I428 HydrophobicContact CZ-CG2 4.2Å; V403-I428 HydrophobicContact CG2-CD1 4.12Å; F426-I428 HydrophobicContact CD2-CG1 4.2Å; F426-I428 HydrophobicContact CE2-CD1 4.25Å; F426-I428 HydrophobicContact CE2-CG1 4.4Å; I428-V448 HydrophobicContact CB-CG2 4.04Å; I428-V448 HydrophobicContact CG2-CG2 3.7Å; I428-V448 VanDerWaalsContact O-CG2 3.28Å; I428-V448 WeakPolarHBondContact O-CG2 3.3Å; I428-V448 PolarHBondContact O-N 3.21Å; I428-A449 HydrophobicContact CB-CB 4.14Å; I428-A449 HydrophobicContact CD1-CB 4.21Å; I428-A449 HydrophobicContact CG1-CB 4.35Å; I428-A449 PolarHBondContact N-O 2.72Å; I428-A449 PolarHBondContact O-N 3.01Å; I428-L461 HydrophobicContact CD1-CD2 4.38Å; I428-L465 HydrophobicContact CG2-CD1 4.44Å; I428-Y470 HydrophobicContact CG2-CD1 4Å; I428-Y470 HydrophobicContact CG2-CG 4.37Å; I428-V471 WeakPolarHBondContact CA-O 3.44Å; I428-L472 HydrophobicContact CG1-CG 4.26Å
429F97.9Very high95.9Very high4 Ų424.3 Ų24.32%0.01813%0.132CC..EExtended strand (participates in β ladder)trans-114136.6176.5-61.2-90.6000110.8F378 F384 E427 V431 L442 Q445 E446 R447 Y470 V471 I473F378-F429 AromaticContact CD2-CZ 3.91Å; F378-F429 HydrophobicContact CD2-CZ 3.91Å; F378-F429 AromaticContact CE2-CE1 3.99Å; F378-F429 HydrophobicContact CE2-CE1 3.99Å; F378-F429 AromaticContact CE2-CZ 3.6Å; F378-F429 HydrophobicContact CE2-CZ 3.6Å; F384-F429 AromaticContact CE1-CE2 3.76Å; F384-F429 HydrophobicContact CE1-CE2 3.76Å; F384-F429 AromaticContact CE1-CZ 3.89Å; F384-F429 HydrophobicContact CE1-CZ 3.89Å; F384-F429 AromaticContact CZ-CE2 3.77Å; F384-F429 HydrophobicContact CZ-CE2 3.77Å; F384-F429 HydrophobicContact CZ-CZ 4.1Å; E427-F429 HydrophobicContact CB-CD2 4.31Å; E427-F429 HydrophobicContact CB-CE2 3.46Å; E427-F429 VanDerWaalsContact CB-CE2 3.46Å; E427-F429 HydrophobicContact CB-CZ 3.95Å; E427-F429 HydrophobicContact CG-CE2 4.39Å; F429-V431 HydrophobicContact CB-CG1 4.2Å; F429-L442 HydrophobicContact CD1-CD2 3.75Å; F429-L442 HydrophobicContact CE1-CD1 3.81Å; F429-L442 HydrophobicContact CE1-CD2 3.78Å; F429-L442 HydrophobicContact CE1-CG 4.45Å; F429-L442 HydrophobicContact CG-CD2 4.19Å; F429-L442 HydrophobicContact CZ-CD1 3.97Å; F429-L442 HydrophobicContact CZ-CD2 4.26Å; F429-Q445 HydrophobicContact CB-CB 4.44Å; F429-E446 CarbonylContact C-O 3.48Å; F429-E446 WeakPolarHBondContact CA-O 3.34Å; F429-R447 HydrophobicContact CD1-CB 3.9Å; F429-R447 HydrophobicContact CD1-CG 4.33Å; F429-R447 HydrophobicContact CE1-CB 3.62Å; F429-R447 HydrophobicContact CE1-CG 3.85Å; F429-R447 HydrophobicContact CZ-CB 4.45Å; F429-R447 HydrophobicContact CZ-CG 4.19Å; F429-Y470 CarbonylContact O-C 3.59Å; F429-Y470 WeakPolarHBondContact O-CA 2.97Å; F429-V471 PolarHBondContact N-O 3.47Å; F429-V471 PolarHBondContact O-N 3.11Å; F429-I473 HydrophobicContact CD2-CD1 4.19Å; F429-I473 HydrophobicContact CE2-CD1 4.08Å
430K96.9Very high96.3Very high14 Ų1425.5 Ų25.56%0.06113%0.134CC..EExtended strand (participates in β ladder)trans-75.6129.7162.4-174.6167.5179165.50108.6Q445 E446 V448 Q467 Y470 D567K430-Q445 WeakPolarHBondContact O-CA 3.46Å; K430-E446 HydrophobicContact CB-CB 4.5Å; K430-E446 PolarHBondContact N-O 3.48Å; K430-E446 PolarHBondContact O-N 3.29Å; K430-V448 HydrophobicContact CB-CG1 3.88Å; K430-Q467 PolarHBondContact NZ-O 2.94Å; K430-Y470 HydrophobicContact CB-CD1 4.07Å; K430-Y470 HydrophobicContact CB-CE1 3.78Å; K430-Y470 HydrophobicContact CD-CE1 4.39Å; K430-Y470 HydrophobicContact CG-CE1 4.09Å; K430-D567 WeakPolarHBondContact CD-OD2 3.3Å; K430-D567 WeakPolarHBondContact CE-OD2 3.4Å; K430-D567 IonicContact NZ-OD2 3.55Å; K430-D567 PolarHBondContact NZ-OD2 3.47Å
431V96.9Very high96.5Very high1 Ų121.4 Ų21.41%0.00611%0.113CC..EExtended strand (participates in β ladder)trans-128.1-178.4-175.1-54.80000111F429 R435 L439 Q445 R469 V471F429-V431 HydrophobicContact CB-CG1 4.2Å; V431-R435 HydrophobicContact CG2-CB 4.3Å; V431-L439 HydrophobicContact CG1-CD2 4.48Å; V431-Q445 HydrophobicContact CB-CG 4.38Å; V431-Q445 HydrophobicContact CG1-CG 3.88Å; V431-R469 HydrophobicContact CG2-CB 4.29Å; V431-R469 HydrophobicContact CG2-CG 3.71Å; V431-R469 PolarHBondContact N-O 2.95Å; V431-V471 HydrophobicContact CB-CG2 4.35Å; V431-V471 HydrophobicContact CG1-CB 3.94Å; V431-V471 HydrophobicContact CG1-CG2 3.67Å; V431-V471 HydrophobicContact CG2-CG2 3.84Å
432E96.9Very high96.4Very high0 Ų022.8 Ų22.80%012%0.117CC..  trans-63.7135.9-179.2-52.991.2144.600112.4N434 R435 Q445 R469 Q522 Q569 I571E432-N434 PolarHBondContact O-N 3.18Å; E432-R435 HydrophobicContact CB-CB 4.2Å; E432-R435 WeakPolarHBondContact O-CB 3.27Å; E432-R435 PolarHBondContact O-N 2.86Å; E432-R435 IonicContact OE1-CZ 2.74Å; E432-R435 IonicContact OE1-NE 3.27Å; E432-R435 IonicContact OE1-NH2 3.65Å; E432-R435 PolarHBondContact OE1-NH2 3.25Å; E432-R435 IonicContact OE2-CZ 2.81Å; E432-R435 IonicContact OE2-NE 3.43Å; E432-R435 PolarHBondContact OE2-NE 2.82Å; E432-R435 IonicContact OE2-NH2 2.82Å; E432-R435 PolarHBondContact OE2-NH2 3.43Å; E432-Q445 PolarHBondContact OE1-NE2 2.9Å; E432-Q445 PolarHBondContact OE2-NE2 3Å; E432-R469 VanDerWaalsContact O-CD 3.28Å; E432-R469 WeakPolarHBondContact O-CD 3.43Å; E432-Q522 VanDerWaalsContact OE1-CD 3.31Å; E432-Q522 VanDerWaalsContact OE1-CG 3.31Å; E432-Q522 WeakPolarHBondContact OE1-CG 3.26Å; E432-Q522 PolarHBondContact OE1-NE2 2.94Å; E432-Q569 CarbonylContact C-O 3.54Å; E432-Q569 VanDerWaalsContact CA-O 3.27Å; E432-Q569 WeakPolarHBondContact CA-O 3.24Å; E432-Q569 HydrophobicContact CB-CB 4.29Å; E432-Q569 HydrophobicContact CG-CB 3.94Å; E432-I571 HydrophobicContact CB-CB 4.15Å; E432-I571 HydrophobicContact CB-CG2 3.84Å; E432-I571 HydrophobicContact CG-CB 3.9Å; E432-I571 HydrophobicContact CG-CG2 4.12Å
433D95.3Very high96Very high47 Ų4722.9 Ų22.925%0.25112%0.12SC..THydrogen-bonded Turntrans-62.8-23.2-172.5-66.6-42.2000112.9R469 V553 Q569D433-R469 PolarHBondContact O-NH1 3.14Å; D433-V553 HydrophobicContact CB-CG1 3.88Å; D433-Q569 PolarHBondContact N-O 2.82Å
434N96.3Very high95.5Very high33 Ų3321.1 Ų21.118%0.17611%0.108CC..THydrogen-bonded Turntrans-106.66.8176.769.8-25.9000114.1E432 S436 V553 I571E432-N434 PolarHBondContact O-N 3.18Å; N434-S436 PolarHBondContact O-N 3.34Å; N434-S436 PolarHBondContact O-OG 2.9Å; N434-V553 HydrophobicContact CB-CG2 3.77Å; N434-I571 PolarHBondContact ND2-O 3Å; N434-I571 PolarHBondContact OD1-N 2.93Å; N434-I571 PolarHBondContact OD1-O 3.23Å
435R96.3Very high95.3Very high1 Ų122.1 Ų22.10%0.00411%0.112CC..  trans-57.4132.9179.8-179.8166.7-75.5-95.69.3110.8I391 V431 E432 Y437 R438 R469 I571 L644I391-R435 HydrophobicContact CD1-CB 4.25Å; I391-R435 HydrophobicContact CD1-CG 4.28Å; I391-R435 WeakPolarHBondContact CD1-O 3.07Å; V431-R435 HydrophobicContact CG2-CB 4.3Å; E432-R435 HydrophobicContact CB-CB 4.2Å; E432-R435 WeakPolarHBondContact O-CB 3.27Å; E432-R435 PolarHBondContact O-N 2.86Å; E432-R435 IonicContact OE1-CZ 2.74Å; E432-R435 IonicContact OE1-NE 3.27Å; E432-R435 IonicContact OE1-NH2 3.65Å; E432-R435 PolarHBondContact OE1-NH2 3.25Å; E432-R435 IonicContact OE2-CZ 2.81Å; E432-R435 IonicContact OE2-NE 3.43Å; E432-R435 PolarHBondContact OE2-NE 2.82Å; E432-R435 IonicContact OE2-NH2 2.82Å; E432-R435 PolarHBondContact OE2-NH2 3.43Å; R435-Y437 WeakPolarHBondContact CD-O 3.3Å; R435-Y437 WeakPolarHBondContact CG-O 3.48Å; R435-Y437 PolarHBondContact NH1-O 3.06Å; R435-R438 PolarHBondContact NH1-O 2.92Å; R435-R469 PolarHBondContact O-NH1 3.47Å; R435-I571 HydrophobicContact CB-CG2 4.12Å; R435-L644 PolarHBondContact NH2-OXT 2.81Å
436S95.9Very high95Very high56 Ų5626.5 Ų26.539%0.39213%0.133SC..  trans-131.7-13.5-179-64.30000114.1N434 L500N434-S436 PolarHBondContact O-N 3.34Å; N434-S436 PolarHBondContact O-OG 2.9Å; S436-L500 WeakPolarHBondContact O-CD2 3.45Å
437Y97.2Very high94.9Very high64 Ų6432.3 Ų32.325%0.25116%0.155SC..SBendtrans-118.2164.7-176.6-53.4-74.6000110.7R435 A502 K504 P505 Y573R435-Y437 WeakPolarHBondContact CD-O 3.3Å; R435-Y437 WeakPolarHBondContact CG-O 3.48Å; R435-Y437 PolarHBondContact NH1-O 3.06Å; Y437-A502 WeakPolarHBondContact CA-O 3.47Å; Y437-A502 WeakPolarHBondContact CB-O 3.46Å; Y437-A502 HydrophobicContact CD1-CB 3.93Å; Y437-A502 HydrophobicContact CE1-CB 4.38Å; Y437-K504 VanDerWaalsContact CD1-C 3.47Å; Y437-K504 VanDerWaalsContact CE1-C 3.45Å; Y437-K504 WeakPolarHBondContact CE1-O 3.46Å; Y437-P505 HydrophobicContact CE1-CG 4.33Å; Y437-P505 HydrophobicContact CE2-CG 3.68Å; Y437-P505 WeakPolarHBondContact OH-CA 3.19Å; Y437-P505 WeakPolarHBondContact OH-CG 3.39Å; Y437-Y573 HydrophobicContact CD2-CD2 4.03Å; Y437-Y573 HydrophobicContact CD2-CE1 4.43Å; Y437-Y573 AromaticContact CD2-CE2 3.37Å; Y437-Y573 HydrophobicContact CD2-CE2 3.37Å; Y437-Y573 AromaticContact CD2-CZ 3.59Å; Y437-Y573 AromaticContact CE2-CD2 3.98Å; Y437-Y573 HydrophobicContact CE2-CD2 3.98Å; Y437-Y573 AromaticContact CE2-CE2 3.82Å; Y437-Y573 HydrophobicContact CE2-CE2 3.82Å; Y437-Y573 HydrophobicContact CG-CE2 4.4Å
438R97.5Very high94.9Very high4 Ų433.6 Ų33.62%0.01516%0.163CC..  trans-54.4145.9178.6-68.6176.860.479.53.7111.5L385 Q386 N387 R435 H440 L500 A502 D503L385-R438 PolarHBondContact O-NH2 2.84Å; Q386-R438 PolarHBondContact O-NH2 3.39Å; N387-R438 PolarHBondContact O-NH1 2.94Å; N387-R438 PolarHBondContact O-NH2 2.91Å; R435-R438 PolarHBondContact NH1-O 2.92Å; R438-H440 PolarHBondContact O-CD2 3.46Å; R438-H440 PolarHBondContact O-NE2 3.17Å; R438-L500 VanDerWaalsContact CD-O 3.28Å; R438-L500 WeakPolarHBondContact CD-O 3.41Å; R438-L500 HydrophobicContact CG-CB 3.84Å; R438-L500 WeakPolarHBondContact CG-O 3.26Å; R438-L500 PolarHBondContact NH1-O 2.81Å; R438-A502 PolarHBondContact N-O 3.01Å; R438-D503 VanDerWaalsContact CD-OD1 3.24Å; R438-D503 WeakPolarHBondContact CD-OD1 3.39Å; R438-D503 IonicContact NE-OD1 3.5Å; R438-D503 PolarHBondContact NE-OD1 2.96Å
439L96.2Very high94.8Very high0 Ų034 Ų340%017%0.166CC..  trans-84.6123.7174.7-178.265.9000108.8L385 Q389 V431 K441 L442 Q445L385-L439 HydrophobicContact CD2-CD2 4.12Å; L385-L439 HydrophobicContact CD2-CG 4.25Å; Q389-L439 PolarHBondContact NE2-O 2.86Å; V431-L439 HydrophobicContact CG1-CD2 4.48Å; L439-K441 VanDerWaalsContact CD1-O 3.29Å; L439-K441 WeakPolarHBondContact CD1-O 3.42Å; L439-L442 HydrophobicContact CD2-CD2 3.62Å; L439-L442 HydrophobicContact CG-CD2 4.4Å; L439-Q445 HydrophobicContact CD1-CG 3.94Å; L439-Q445 HydrophobicContact CD2-CG 4.32Å
440H94.8Very high94.7Very high37 Ų3737.1 Ų37.117%0.17119%0.186CC..  trans-110.9-15.7-176.8-59.6-64.7000113.7L385 R438 D503 V642L385-H440 VanDerWaalsContact CD1-O 3.22Å; L385-H440 WeakPolarHBondContact CD1-O 3.35Å; R438-H440 PolarHBondContact O-CD2 3.46Å; R438-H440 PolarHBondContact O-NE2 3.17Å; H440-D503 IonicContact CE1-OD1 3.26Å; H440-D503 PolarHBondContact CE1-OD1 3.19Å; H440-D503 VanDerWaalsContact CE1-OD1 3.27Å; H440-D503 PolarHBondContact NE2-O 3.22Å; H440-V642 WeakPolarHBondContact CB-O 3.26Å; H440-V642 PolarHBondContact CD2-O 2.91Å
441K92.5Very high94.7Very high78 Ų7836.8 Ų36.834%0.33919%0.185SC..  trans-152147.8178.8-161.3169-172.9159.20111.1L439 T443 Q445 E643L439-K441 VanDerWaalsContact CD1-O 3.29Å; L439-K441 WeakPolarHBondContact CD1-O 3.42Å; K441-T443 HydrophobicContact CB-CG2 4.14Å; K441-T443 HydrophobicContact CD-CG2 3.8Å; K441-T443 HydrophobicContact CG-CG2 3.69Å; K441-Q445 PolarHBondContact O-OE1 3.37Å; K441-E643 WeakPolarHBondContact CB-O 3.33Å; K441-E643 HydrophobicContact CD-CG 4.46Å; K441-E643 WeakPolarHBondContact CD-O 3.15Å; K441-E643 IonicContact NZ-OE1 3.44Å; K441-E643 PolarHBondContact NZ-OE1 2.87Å
442L92.1Very high94.4Very high64 Ų6442.4 Ų42.434%0.33521%0.213SC..  trans-100.983.2177.5-63.6172.3000109.1F378 L385 F429 L439 Q445F378-L442 HydrophobicContact CE2-CD1 3.58Å; F378-L442 HydrophobicContact CZ-CD1 4.21Å; L385-L442 HydrophobicContact CD1-CG 4.33Å; L385-L442 HydrophobicContact CD2-CD2 4.47Å; L385-L442 HydrophobicContact CD2-CG 4.47Å; F429-L442 HydrophobicContact CD1-CD2 3.75Å; F429-L442 HydrophobicContact CE1-CD1 3.81Å; F429-L442 HydrophobicContact CE1-CD2 3.78Å; F429-L442 HydrophobicContact CE1-CG 4.45Å; F429-L442 HydrophobicContact CG-CD2 4.19Å; F429-L442 HydrophobicContact CZ-CD1 3.97Å; F429-L442 HydrophobicContact CZ-CD2 4.26Å; L439-L442 HydrophobicContact CD2-CD2 3.62Å; L439-L442 HydrophobicContact CG-CD2 4.4Å; L442-Q445 HydrophobicContact CD2-CB 4.04Å
443T86.2Confident94.3Very high29 Ų2945 Ų4518%0.17822%0.223CC..SBendtrans-101.6-47.4-175.254.40000112.4K441 Q522 F636 L644K441-T443 HydrophobicContact CB-CG2 4.14Å; K441-T443 HydrophobicContact CD-CG2 3.8Å; K441-T443 HydrophobicContact CG-CG2 3.69Å; T443-Q522 PolarHBondContact OG1-OE1 2.97Å; T443-F636 HydrophobicContact CG2-CD1 4.4Å; T443-L644 HydrophobicContact CG2-CD2 4.25Å
444V86.3Confident94Very high9 Ų945.4 Ų45.46%0.05522%0.224CC..SBendtrans-121.6-14-176.2-64.40000112.6Q522 K524 Q569 F636V444-Q522 HydrophobicContact CG2-CB 4.5Å; V444-K524 HydrophobicContact CB-CB 4.28Å; V444-K524 HydrophobicContact CB-CD 4.38Å; V444-K524 HydrophobicContact CG1-CB 4.23Å; V444-Q569 PolarHBondContact O-NE2 2.72Å; V444-F636 HydrophobicContact CG1-CD2 3.57Å; V444-F636 HydrophobicContact CG1-CE2 3.43Å; V444-F636 VanDerWaalsContact CG1-CE2 3.43Å
445Q93.8Very high93.8Very high20 Ų2049.1 Ų49.19%0.09325%0.245CC..  trans-68.3139.6-177.5-66.872.225.300110.3F429 K430 V431 E432 L439 K441 L442 Q522F429-Q445 HydrophobicContact CB-CB 4.44Å; K430-Q445 WeakPolarHBondContact O-CA 3.46Å; V431-Q445 HydrophobicContact CB-CG 4.38Å; V431-Q445 HydrophobicContact CG1-CG 3.88Å; E432-Q445 PolarHBondContact OE1-NE2 2.9Å; E432-Q445 PolarHBondContact OE2-NE2 3Å; L439-Q445 HydrophobicContact CD1-CG 3.94Å; L439-Q445 HydrophobicContact CD2-CG 4.32Å; K441-Q445 PolarHBondContact O-OE1 3.37Å; L442-Q445 HydrophobicContact CD2-CB 4.04Å; Q445-Q522 VanDerWaalsContact NE2-NE2 3.11Å
446E92.3Very high93.5Very high92 Ų9251.5 Ų51.543%0.4326%0.259SS..EExtended strand (participates in β ladder)trans-103.6128.5178.3-176.6-176.4161.400109.4F429 K430 V448F429-E446 CarbonylContact C-O 3.48Å; F429-E446 WeakPolarHBondContact CA-O 3.34Å; K430-E446 HydrophobicContact CB-CB 4.5Å; K430-E446 PolarHBondContact N-O 3.48Å; K430-E446 PolarHBondContact O-N 3.29Å; E446-V448 HydrophobicContact CB-CG1 4.43Å; E446-V448 HydrophobicContact CG-CG1 4.16Å; E446-V448 PolarHBondContact O-N 3.14Å
447R95.8Very high93.5Very high123 Ų12349.2 Ų49.246%0.46424%0.242SC..EExtended strand (participates in β ladder)trans-76.8102171.3-171.617064.9162.1-2.1109.1F378 E427 F429F378-R447 VanDerWaalsContact CD1-NH1 3.31Å; E427-R447 WeakPolarHBondContact OE2-CD 3.4Å; E427-R447 IonicContact OE2-NH1 3.77Å; F429-R447 HydrophobicContact CD1-CB 3.9Å; F429-R447 HydrophobicContact CD1-CG 4.33Å; F429-R447 HydrophobicContact CE1-CB 3.62Å; F429-R447 HydrophobicContact CE1-CG 3.85Å; F429-R447 HydrophobicContact CZ-CB 4.45Å; F429-R447 HydrophobicContact CZ-CG 4.19Å
448V96.7Very high93.3Very high28 Ų2847 Ų4717%0.1724%0.235CC..EExtended strand (participates in β ladder)trans-90.9-21.8-173.7-65.10000113.3I428 K430 E446 L465 Y470I428-V448 HydrophobicContact CB-CG2 4.04Å; I428-V448 HydrophobicContact CG2-CG2 3.7Å; I428-V448 VanDerWaalsContact O-CG2 3.28Å; I428-V448 WeakPolarHBondContact O-CG2 3.3Å; I428-V448 PolarHBondContact O-N 3.21Å; K430-V448 HydrophobicContact CB-CG1 3.88Å; E446-V448 HydrophobicContact CB-CG1 4.43Å; E446-V448 HydrophobicContact CG-CG1 4.16Å; E446-V448 PolarHBondContact O-N 3.14Å; V448-L465 HydrophobicContact CB-CD2 4.36Å; V448-L465 HydrophobicContact CG2-CD2 4.01Å; V448-Y470 HydrophobicContact CG1-CE1 4.28Å; V448-Y470 HydrophobicContact CG2-CD1 3.86Å; V448-Y470 HydrophobicContact CG2-CE1 3.8Å
449A96.7Very high93.2Very high10 Ų1047 Ų478%0.08324%0.236CC..EExtended strand (participates in β ladder)trans-157.5150.5176.200000112.1I428 L461 R463I428-A449 HydrophobicContact CB-CB 4.14Å; I428-A449 HydrophobicContact CD1-CB 4.21Å; I428-A449 HydrophobicContact CG1-CB 4.35Å; I428-A449 PolarHBondContact N-O 2.72Å; I428-A449 PolarHBondContact O-N 3.01Å; A449-L461 HydrophobicContact CB-CD2 3.82Å; A449-R463 HydrophobicContact CB-CG 4.27Å
450T96.7Very high93.2Very high70 Ų7048.6 Ų48.643%0.42924%0.242SC..EExtended strand (participates in β ladder)trans-132.7138.8172.8-179.20000107.3E427E427-T450 PolarHBondContact OE1-OG1 3.44Å; E427-T450 WeakPolarHBondContact OE2-CA 3.3Å; E427-T450 WeakPolarHBondContact OE2-CB 3.22Å; E427-T450 PolarHBondContact OE2-OG1 2.86Å; E427-T450 VanDerWaalsContact OE2-OG1 3.11Å
451S96Very high93.2Very high6 Ų648.4 Ų48.44%0.04224%0.243CC..  trans-83.8161.9168.878.70000110.3G425 F426G425-S451 WeakPolarHBondContact CA-OG 3.44Å; F426-S451 PolarHBondContact N-OG 3.14Å; F426-S451 PolarHBondContact O-N 3.38Å
452M91.5Very high93.2Very high119 Ų11948.3 Ų48.359%0.58624%0.242SC*.  trans-64.7150.8162.3-64.717968.500109.7I454M452-I454 HydrophobicContact CB-CG2 4.16Å; M452-I454 HydrophobicContact CE-CG2 4.4Å
453Y94.1Very high93.3Very high54 Ų5451.6 Ų51.621%0.21225%0.25CS..  trans-102.7111.1168.8-75.7-101.8000107.9C377 I424 E427 T475 Y477C377-Y453 HydrophobicContact CB-CD1 4.22Å; C377-Y453 HydrophobicContact CB-CE1 3.43Å; C377-Y453 VanDerWaalsContact CB-CE1 3.43Å; C377-Y453 HydrophobicContact CB-CE2 4.35Å; I424-Y453 WeakPolarHBondContact O-CA 3.25Å; E427-Y453 PolarHBondContact OE1-OH 3.04Å; Y453-T475 VanDerWaalsContact CE1-OG1 3.25Å; Y453-T475 WeakPolarHBondContact CE1-OG1 3.44Å; Y453-T475 PolarHBondContact OH-OG1 3.23Å; Y453-Y477 AromaticContact CD1-CD2 3.78Å; Y453-Y477 HydrophobicContact CD1-CD2 3.78Å; Y453-Y477 HydrophobicContact CD1-CG 4.45Å; Y453-Y477 HydrophobicContact CE1-CD2 4.5Å; Y453-Y477 AromaticContact CG-CD2 3.94Å; Y453-Y477 HydrophobicContact CG-CD2 3.94Å
454I90.3Very high93.8Very high56 Ų5654.1 Ų54.129%0.28727%0.265SS..BIsolated β-bridgetrans-136.1148.3-175.255.6174.1000109.4P423 I424 M452 T456 V459P423-I454 WeakPolarHBondContact CA-O 3.09Å; I424-I454 PolarHBondContact N-O 2.9Å; M452-I454 HydrophobicContact CB-CG2 4.16Å; M452-I454 HydrophobicContact CE-CG2 4.4Å; I454-T456 HydrophobicContact CB-CG2 4.34Å; I454-T456 HydrophobicContact CD1-CG2 3.75Å; I454-T456 VanDerWaalsContact CD1-OG1 3.25Å; I454-T456 WeakPolarHBondContact CD1-OG1 3.45Å; I454-T456 HydrophobicContact CG1-CG2 4.1Å; I454-T456 WeakPolarHBondContact CG1-OG1 3.39Å; I454-T456 PolarHBondContact O-N 3Å; I454-V459 HydrophobicContact CD1-CG2 4.16Å; I454-V459 HydrophobicContact CG1-CG2 3.65Å
455N90.4Very high94.3Very high112 Ų11254 Ų5460%0.59927%0.265SS*.SBendtrans-8250.3177.961.6-25.6000111.5S421 P423S421-N455 WeakPolarHBondContact CB-O 3.27Å; P423-N455 HydrophobicContact CG-CB 4.22Å
456T91.6Very high94.3Very high51 Ų5159.6 Ų59.631%0.31329%0.288SS..SBendtrans-112.1162.3175.664.40000110.5Q407 I454 T458Q407-T456 PolarHBondContact NE2-O 3.45Å; I454-T456 HydrophobicContact CB-CG2 4.34Å; I454-T456 HydrophobicContact CD1-CG2 3.75Å; I454-T456 VanDerWaalsContact CD1-OG1 3.25Å; I454-T456 WeakPolarHBondContact CD1-OG1 3.45Å; I454-T456 HydrophobicContact CG1-CG2 4.1Å; I454-T456 WeakPolarHBondContact CG1-OG1 3.39Å; I454-T456 PolarHBondContact O-N 3Å; T456-T458 VanDerWaalsContact C-N 3.25Å; T456-T458 PolarHBondContact O-N 3Å; T456-T458 PolarHBondContact OG1-O 2.77Å
457R94.1Very high94.4Very high8 Ų859 Ų593%0.0329%0.286CS..SBendtrans-67.2-29.2178.1-164.6173.666.4157.111.3112.2D184 D188 Q406 Q407 D409 S421D184-R457 VanDerWaalsContact C-NH2 3.31Å; D184-R457 PolarHBondContact O-NH2 3.34Å; D184-R457 WeakPolarHBondContact OD1-CB 3.36Å; D184-R457 IonicContact OD1-CZ 3.67Å; D184-R457 IonicContact OD1-NE 3.28Å; D184-R457 PolarHBondContact OD1-NE 3.44Å; D184-R457 IonicContact OD1-NH2 3.98Å; D184-R457 PolarHBondContact OD1-NH2 3.12Å; D184-R457 VanDerWaalsContact OD2-CB 3.26Å; D184-R457 WeakPolarHBondContact OD2-CB 3.17Å; D184-R457 IonicContact OD2-NE 2.72Å; D184-R457 PolarHBondContact OD2-NE 2.86Å; D188-R457 IonicContact OD1-CZ 2.78Å; D188-R457 VanDerWaalsContact OD1-CZ 3.3Å; D188-R457 IonicContact OD1-NH1 3.88Å; D188-R457 PolarHBondContact OD1-NH1 3.18Å; D188-R457 IonicContact OD1-NH2 2.72Å; D188-R457 PolarHBondContact OD1-NH2 3.36Å; D188-R457 IonicContact OD2-CZ 2.79Å; D188-R457 IonicContact OD2-NH1 3.88Å; D188-R457 PolarHBondContact OD2-NH1 3.49Å; D188-R457 IonicContact OD2-NH2 2.72Å; Q406-R457 VanDerWaalsContact CA-O 3.31Å; Q406-R457 WeakPolarHBondContact CA-O 3.47Å; Q406-R457 HydrophobicContact CG-CG 4.49Å; Q407-R457 HydrophobicContact CG-CG 4.32Å; Q407-R457 PolarHBondContact N-O 2.87Å; D409-R457 IonicContact OD2-CZ 2.72Å; D409-R457 IonicContact OD2-NH1 2.68Å; D409-R457 PolarHBondContact OD2-NH1 3.11Å; S421-R457 PolarHBondContact OG-N 2.79Å
458T94.5Very high94.4Very high18 Ų1853.7 Ų53.711%0.1127%0.269CS..EExtended strand (participates in β ladder)trans-132.5134.5-178.4-56.30000112S404 L405 Q406 T456S404-T458 WeakPolarHBondContact OG-CG2 3.27Å; L405-T458 CarbonylContact O-C 3.44Å; L405-T458 WeakPolarHBondContact O-CA 3.24Å; Q406-T458 HydrophobicContact CB-CG2 4.33Å; T456-T458 VanDerWaalsContact C-N 3.25Å; T456-T458 PolarHBondContact O-N 3Å; T456-T458 PolarHBondContact OG1-O 2.77Å
459V95.1Very high94.4Very high4 Ų454.4 Ų54.42%0.02427%0.269CS..EExtended strand (participates in β ladder)trans-113.4133.6169.5176.10000109.6S404 L405 I424 F426 I454S404-V459 WeakPolarHBondContact CA-O 3.21Å; L405-V459 PolarHBondContact N-O 3.3Å; L405-V459 PolarHBondContact O-N 2.96Å; I424-V459 HydrophobicContact CD1-CG2 4.3Å; I424-V459 HydrophobicContact CG1-CG2 3.79Å; F426-V459 HydrophobicContact CE1-CG1 4.02Å; I454-V459 HydrophobicContact CD1-CG2 4.16Å; I454-V459 HydrophobicContact CG1-CG2 3.65Å
460F95Very high94.4Very high32 Ų3254.1 Ų54.114%0.1427%0.265CS..EExtended strand (participates in β ladder)trans-124143.1-178.2177.7-95.7000111.6V193 A194 E195 L402 V403 K462V193-F460 HydrophobicContact CG1-CD2 3.42Å; V193-F460 VanDerWaalsContact CG1-CD2 3.42Å; V193-F460 HydrophobicContact CG1-CE2 3.43Å; V193-F460 VanDerWaalsContact CG1-CE2 3.43Å; A194-F460 VanDerWaalsContact O-CB 3.28Å; A194-F460 WeakPolarHBondContact O-CB 3.48Å; E195-F460 HydrophobicContact CB-CD1 3.51Å; E195-F460 HydrophobicContact CB-CE1 3.73Å; E195-F460 HydrophobicContact CB-CG 4.12Å; E195-F460 HydrophobicContact CG-CD1 3.55Å; E195-F460 HydrophobicContact CG-CE1 3.75Å; L402-F460 HydrophobicContact CB-CE2 3.86Å; L402-F460 HydrophobicContact CB-CZ 4.05Å; L402-F460 HydrophobicContact CD1-CZ 4.45Å; L402-F460 HydrophobicContact CD2-CZ 4.04Å; L402-F460 HydrophobicContact CG-CZ 4.41Å; V403-F460 CarbonylContact O-C 3.53Å; V403-F460 WeakPolarHBondContact O-CA 3.5Å; V403-F460 WeakPolarHBondContact O-CD2 3.26Å; F460-K462 HydrophobicContact CE1-CB 3.76Å; F460-K462 HydrophobicContact CZ-CB 4.12Å
461L94.9Very high94.5Very high33 Ų3350.8 Ų50.817%0.17325%0.245CC..EExtended strand (participates in β ladder)trans-137.6135.6171.2-174.267.9000110.6L402 V403 F426 I428 A449L402-L461 WeakPolarHBondContact CA-O 3.48Å; V403-L461 PolarHBondContact N-O 3.43Å; V403-L461 PolarHBondContact O-N 3.15Å; F426-L461 HydrophobicContact CE2-CB 3.86Å; F426-L461 HydrophobicContact CE2-CD2 3.75Å; F426-L461 HydrophobicContact CE2-CG 4.49Å; F426-L461 HydrophobicContact CZ-CB 3.46Å; F426-L461 VanDerWaalsContact CZ-CB 3.46Å; F426-L461 HydrophobicContact CZ-CD2 4.23Å; I428-L461 HydrophobicContact CD1-CD2 4.38Å; A449-L461 HydrophobicContact CB-CD2 3.82Å
462K93.3Very high94.7Very high76 Ų7650.5 Ų50.533%0.3324%0.243SC..EExtended strand (participates in β ladder)trans-116.3119.4171.9173175.370.8-145.20108.7E195 K400 L402 F460E195-K462 IonicContact OE1-NZ 3.42Å; E195-K462 PolarHBondContact OE1-NZ 2.74Å; E195-K462 IonicContact OE2-NZ 3.98Å; E195-K462 PolarHBondContact OE2-NZ 3.17Å; K400-K462 HydrophobicContact CD-CG 4.38Å; K400-K462 HydrophobicContact CG-CG 4.48Å; L402-K462 HydrophobicContact CD2-CB 3.84Å; L402-K462 HydrophobicContact CD2-CD 4.09Å; L402-K462 HydrophobicContact CD2-CG 3.59Å; F460-K462 HydrophobicContact CE1-CB 3.76Å; F460-K462 HydrophobicContact CZ-CB 4.12Å
463R94.8Very high95Very high134 Ų13444.8 Ų44.851%0.50622%0.215SC..EExtended strand (participates in β ladder)trans-140.5146.4-178.3-159.770.1174.5179.80.3111.2V401 A449 L465V401-R463 PolarHBondContact N-O 3.2Å; V401-R463 PolarHBondContact O-N 3.39Å; A449-R463 HydrophobicContact CB-CG 4.27Å; R463-L465 HydrophobicContact CB-CD2 4.44Å; R463-L465 HydrophobicContact CG-CD2 3.89Å
464V96Very high95.2Very high82 Ų8242.2 Ų42.250%0.49721%0.205SC..EExtended strand (participates in β ladder)trans-91.4123.3165.7-1780000107.5E398 D399E398-V464 HydrophobicContact CB-CG1 3.99Å; D399-V464 WeakPolarHBondContact O-CA 3.49Å
465L96.1Very high95.6Very high7 Ų739.6 Ų39.64%0.03719%0.191CC..EExtended strand (participates in β ladder)trans-115.2143.6178.3-63.2-175.8000109.4F392 V394 E398 D399 V401 I428 V448 R463 Y470F392-L465 HydrophobicContact CE2-CD1 4.2Å; F392-L465 HydrophobicContact CZ-CD1 3.97Å; V394-L465 HydrophobicContact CG2-CB 4.11Å; V394-L465 HydrophobicContact CG2-CD1 4.46Å; E398-L465 CarbonylContact C-O 3.44Å; E398-L465 WeakPolarHBondContact CA-O 3.36Å; D399-L465 PolarHBondContact N-O 3.07Å; D399-L465 PolarHBondContact O-N 2.82Å; V401-L465 HydrophobicContact CB-CD1 4.25Å; V401-L465 HydrophobicContact CB-CG 4.49Å; V401-L465 HydrophobicContact CG2-CB 4.22Å; V401-L465 HydrophobicContact CG2-CD1 3.91Å; V401-L465 HydrophobicContact CG2-CG 4.11Å; I428-L465 HydrophobicContact CG2-CD1 4.44Å; V448-L465 HydrophobicContact CB-CD2 4.36Å; V448-L465 HydrophobicContact CG2-CD2 4.01Å; R463-L465 HydrophobicContact CB-CD2 4.44Å; R463-L465 HydrophobicContact CG-CD2 3.89Å; L465-Y470 HydrophobicContact CB-CE2 4.36Å; L465-Y470 HydrophobicContact CD1-CD1 4.23Å; L465-Y470 HydrophobicContact CD1-CD2 4.39Å; L465-Y470 HydrophobicContact CD1-CE1 4.2Å; L465-Y470 HydrophobicContact CD1-CE2 4.37Å; L465-Y470 HydrophobicContact CD1-CG 4.33Å; L465-Y470 HydrophobicContact CD2-CE1 4.49Å
466K94.5Very high96Very high136 Ų13634.2 Ų34.259%0.59116%0.163SC*.EExtended strand (participates in β ladder)trans-72.2169.6173.2-68.9-176.4177.3-178.30110.9V394 T397 E398 G468 Y470V394-K466 WeakPolarHBondContact CB-O 3.41Å; V394-K466 WeakPolarHBondContact CG1-O 3.19Å; T397-K466 CarbonylContact O-C 3.58Å; T397-K466 WeakPolarHBondContact O-CA 3.49Å; E398-K466 HydrophobicContact CG-CG 4.25Å; K466-G468 PolarHBondContact O-N 2.82Å; K466-Y470 PolarHBondContact O-OH 3.43Å
467Q94.3Very high96.2Very high80 Ų8036.1 Ų36.137%0.37417%0.165SC..EExtended strand (participates in β ladder)trans-55.8136170.3-162.2177.66.400111V394 K395 K396 T397 K430V394-Q467 WeakPolarHBondContact O-CA 3.39Å; V394-Q467 WeakPolarHBondContact O-CG 3.44Å; K395-Q467 PolarHBondContact O-NE2 2.98Å; K396-Q467 VanDerWaalsContact O-CA 3.31Å; K396-Q467 WeakPolarHBondContact O-CA 3.48Å; K396-Q467 WeakPolarHBondContact O-CB 3.41Å; K396-Q467 PolarHBondContact O-N 3.33Å; T397-Q467 PolarHBondContact O-N 2.78Å; K430-Q467 PolarHBondContact NZ-O 2.94Å
468G94.9Very high96.3Very high11 Ų1141.2 Ų41.211%0.11319%0.189CC..EExtended strand (participates in β ladder)trans155.1-174.5176.300000113.5V394 K466 Y470V394-G468 PolarHBondContact N-O 3.36Å; V394-G468 PolarHBondContact O-N 2.94Å; K466-G468 PolarHBondContact O-N 2.82Å; G468-Y470 WeakPolarHBondContact O-CE2 3.36Å
469R97.1Very high96.5Very high43 Ų4343.1 Ų43.116%0.16220%0.201CC..EExtended strand (participates in β ladder)trans-106.8139.4175.5179.5164.5-84.9171.818.9110.9I391 D393 V431 E432 D433 R435I391-R469 HydrophobicContact CD1-CG 3.8Å; I391-R469 HydrophobicContact CG1-CG 3.81Å; D393-R469 IonicContact OD1-CZ 3.74Å; D393-R469 IonicContact OD1-NE 3.66Å; D393-R469 PolarHBondContact OD1-NE 3.48Å; D393-R469 IonicContact OD1-NH2 2.73Å; D393-R469 PolarHBondContact OD1-NH2 2.72Å; D393-R469 VanDerWaalsContact OD1-NH2 3.12Å; D393-R469 IonicContact OD2-NH2 3.82Å; D393-R469 PolarHBondContact OD2-NH2 3.28Å; D393-R469 VanDerWaalsContact OD2-NH2 3.13Å; V431-R469 HydrophobicContact CG2-CB 4.29Å; V431-R469 HydrophobicContact CG2-CG 3.71Å; V431-R469 PolarHBondContact N-O 2.95Å; E432-R469 VanDerWaalsContact O-CD 3.28Å; E432-R469 WeakPolarHBondContact O-CD 3.43Å; D433-R469 PolarHBondContact O-NH1 3.14Å; R435-R469 PolarHBondContact O-NH1 3.47Å
470Y98.2Very high96.5Very high4 Ų444.6 Ų44.62%0.01622%0.218CC..EExtended strand (participates in β ladder)trans-132.2146.1-172.6-62.3-85.9000111.9I391 F392 V394 I428 F429 K430 V448 L465 K466 G468I391-Y470 CarbonylContact C-O 3.53Å; I391-Y470 VanDerWaalsContact CA-O 3.29Å; I391-Y470 WeakPolarHBondContact CA-O 3.38Å; I391-Y470 WeakPolarHBondContact CG1-O 3.19Å; F392-Y470 VanDerWaalsContact CE1-CB 3.43Å; F392-Y470 HydrophobicContact CE1-CG 4.39Å; F392-Y470 HydrophobicContact CE2-CD2 4.05Å; F392-Y470 HydrophobicContact CE2-CG 4.25Å; F392-Y470 VanDerWaalsContact CZ-CB 3.48Å; F392-Y470 HydrophobicContact CZ-CD2 4.22Å; F392-Y470 AromaticContact CZ-CG 3.95Å; F392-Y470 HydrophobicContact CZ-CG 3.95Å; F392-Y470 PolarHBondContact N-O 2.75Å; F392-Y470 PolarHBondContact O-N 2.89Å; V394-Y470 HydrophobicContact CB-CD2 4.43Å; V394-Y470 HydrophobicContact CB-CE2 3.89Å; V394-Y470 HydrophobicContact CG2-CD2 3.86Å; V394-Y470 HydrophobicContact CG2-CE2 3.61Å; I428-Y470 HydrophobicContact CG2-CD1 4Å; I428-Y470 HydrophobicContact CG2-CG 4.37Å; F429-Y470 CarbonylContact O-C 3.59Å; F429-Y470 WeakPolarHBondContact O-CA 2.97Å; K430-Y470 HydrophobicContact CB-CD1 4.07Å; K430-Y470 HydrophobicContact CB-CE1 3.78Å; K430-Y470 HydrophobicContact CD-CE1 4.39Å; K430-Y470 HydrophobicContact CG-CE1 4.09Å; V448-Y470 HydrophobicContact CG1-CE1 4.28Å; V448-Y470 HydrophobicContact CG2-CD1 3.86Å; V448-Y470 HydrophobicContact CG2-CE1 3.8Å; L465-Y470 HydrophobicContact CB-CE2 4.36Å; L465-Y470 HydrophobicContact CD1-CD1 4.23Å; L465-Y470 HydrophobicContact CD1-CD2 4.39Å; L465-Y470 HydrophobicContact CD1-CE1 4.2Å; L465-Y470 HydrophobicContact CD1-CE2 4.37Å; L465-Y470 HydrophobicContact CD1-CG 4.33Å; L465-Y470 HydrophobicContact CD2-CE1 4.49Å; K466-Y470 PolarHBondContact O-OH 3.43Å; G468-Y470 WeakPolarHBondContact O-CE2 3.36Å
471V98.5Very high96.6Very high0 Ų045.9 Ų45.90%023%0.225CC..EExtended strand (participates in β ladder)trans-112.1125.7167.3174.20000109Q389 Y390 I391 I428 F429 V431 I473 L500Q389-V471 HydrophobicContact CB-CG1 3.98Å; Q389-V471 HydrophobicContact CG-CG1 4.44Å; Y390-V471 CarbonylContact O-C 3.46Å; Y390-V471 WeakPolarHBondContact O-CA 3.45Å; I391-V471 HydrophobicContact CB-CG2 4.45Å; I391-V471 HydrophobicContact CD1-CG2 4.4Å; I391-V471 HydrophobicContact CG1-CG2 4.14Å; I428-V471 WeakPolarHBondContact CA-O 3.44Å; F429-V471 PolarHBondContact N-O 3.47Å; F429-V471 PolarHBondContact O-N 3.11Å; V431-V471 HydrophobicContact CB-CG2 4.35Å; V431-V471 HydrophobicContact CG1-CB 3.94Å; V431-V471 HydrophobicContact CG1-CG2 3.67Å; V431-V471 HydrophobicContact CG2-CG2 3.84Å; V471-I473 HydrophobicContact CG1-CD1 4.18Å; V471-I473 HydrophobicContact CG1-CG1 3.77Å; V471-L500 HydrophobicContact CG2-CD1 3.87Å
472L98.6Very high96.6Very high0 Ų049.4 Ų49.40%024%0.243CC..EExtended strand (participates in β ladder)trans-104.4124.4174.9-171.7166.6000108.7Y390 F392 V403 F426 E427 I428 P474 L487Y390-L472 PolarHBondContact N-O 3.04Å; Y390-L472 PolarHBondContact O-N 3.22Å; F392-L472 HydrophobicContact CD1-CB 4.46Å; F392-L472 HydrophobicContact CE1-CB 4.13Å; F392-L472 HydrophobicContact CE1-CD1 4.48Å; V403-L472 HydrophobicContact CB-CD1 4.46Å; V403-L472 HydrophobicContact CG1-CD1 3.67Å; V403-L472 HydrophobicContact CG2-CD1 3.89Å; F426-L472 HydrophobicContact CB-CD2 4.1Å; F426-L472 HydrophobicContact CD2-CD2 4.44Å; F426-L472 HydrophobicContact CD2-CG 4.35Å; F426-L472 HydrophobicContact CG-CD2 4.37Å; E427-L472 WeakPolarHBondContact O-CA 3.33Å; I428-L472 HydrophobicContact CG1-CG 4.26Å; L472-P474 HydrophobicContact CD2-CG 4.47Å; L472-L487 HydrophobicContact CD1-CD1 4.03Å; L472-L487 HydrophobicContact CD1-CD2 4.18Å; L472-L487 HydrophobicContact CD2-CD1 3.77Å; L472-L487 HydrophobicContact CD2-CD2 3.71Å; L472-L487 HydrophobicContact CD2-CG 4.4Å; L472-L487 HydrophobicContact CG-CD2 4.49Å
473I98.7Very high96.7Very high0 Ų046.4 Ų46.40%023%0.231CC..EExtended strand (participates in β ladder)trans-11899.2-176.7-52.6-174.2000108.8F384 L385 N387 Q389 F426 E427 F429 V471 T475F384-I473 HydrophobicContact CE1-CD1 3.75Å; F384-I473 HydrophobicContact CE2-CB 4.43Å; F384-I473 HydrophobicContact CE2-CG2 4Å; F384-I473 HydrophobicContact CZ-CB 3.95Å; F384-I473 HydrophobicContact CZ-CD1 3.87Å; F384-I473 HydrophobicContact CZ-CG1 4.43Å; F384-I473 HydrophobicContact CZ-CG2 3.88Å; L385-I473 HydrophobicContact CD2-CD1 3.67Å; N387-I473 HydrophobicContact CB-CG2 3.65Å; Q389-I473 HydrophobicContact CG-CD1 4.26Å; Q389-I473 HydrophobicContact CG-CG1 4.22Å; F426-I473 VanDerWaalsContact CA-O 3.22Å; F426-I473 WeakPolarHBondContact CA-O 3.44Å; F426-I473 WeakPolarHBondContact CB-O 3.22Å; E427-I473 PolarHBondContact N-O 3.21Å; E427-I473 VanDerWaalsContact N-O 3.11Å; E427-I473 PolarHBondContact O-N 3.24Å; F429-I473 HydrophobicContact CD2-CD1 4.19Å; F429-I473 HydrophobicContact CE2-CD1 4.08Å; V471-I473 HydrophobicContact CG1-CD1 4.18Å; V471-I473 HydrophobicContact CG1-CG1 3.77Å; I473-T475 HydrophobicContact CG2-CG2 3.94Å
474P98.6Very high96.8Very high0 Ų045.4 Ų45.40%023%0.23CC..EExtended strand (participates in β ladder)trans-76.3137.1172.431.6-33.8000111.2W363 P388 Y390 L405 F426 L472 F485W363-P474 HydrophobicContact CZ2-CB 4.24Å; W363-P474 PolarHBondContact NE1-O 3.02Å; P388-P474 WeakPolarHBondContact O-CD 3.23Å; Y390-P474 HydrophobicContact CD2-CG 4.01Å; Y390-P474 HydrophobicContact CE2-CG 3.74Å; L405-P474 HydrophobicContact CD1-CB 3.63Å; L405-P474 HydrophobicContact CD2-CB 3.8Å; L405-P474 HydrophobicContact CG-CB 4.35Å; F426-P474 HydrophobicContact CB-CB 4.44Å; L472-P474 HydrophobicContact CD2-CG 4.47Å; P474-F485 HydrophobicContact CB-CE2 4.2Å; P474-F485 HydrophobicContact CB-CZ 4.32Å; P474-F485 HydrophobicContact CG-CD2 4.41Å; P474-F485 HydrophobicContact CG-CE1 4.3Å; P474-F485 HydrophobicContact CG-CE2 3.62Å; P474-F485 HydrophobicContact CG-CZ 3.55Å
475T98.3Very high96.9Very high0 Ų041.5 Ų41.50%021%0.207CC..EExtended strand (participates in β ladder)trans-140.8152.2-174.171.70000111.5W363 G376 F384 N387 I424 G425 Y453 I473W363-T475 VanDerWaalsContact CZ2-C 3.43Å; G376-T475 WeakPolarHBondContact O-CB 3.31Å; G376-T475 WeakPolarHBondContact O-CG2 3.46Å; F384-T475 HydrophobicContact CD2-CG2 4Å; F384-T475 HydrophobicContact CE2-CG2 3.67Å; N387-T475 HydrophobicContact CB-CG2 4.12Å; N387-T475 VanDerWaalsContact ND2-CG2 3.34Å; N387-T475 WeakPolarHBondContact ND2-CG2 3.47Å; I424-T475 WeakPolarHBondContact CA-O 3.06Å; G425-T475 PolarHBondContact N-O 3.43Å; G425-T475 PolarHBondContact O-N 2.97Å; G425-T475 PolarHBondContact O-OG1 3.49Å; Y453-T475 VanDerWaalsContact CE1-OG1 3.25Å; Y453-T475 WeakPolarHBondContact CE1-OG1 3.44Å; Y453-T475 PolarHBondContact OH-OG1 3.23Å; I473-T475 HydrophobicContact CG2-CG2 3.94Å
476T98.1Very high97Very high0 Ų041.1 Ų41.10%021%0.205CC..EExtended strand (participates in β ladder)trans-80.2157.6154.651.50000108.9W363 G376 C377 I422 I424 H478 I481W363-T476 HydrophobicContact CD2-CG2 3.79Å; W363-T476 HydrophobicContact CE3-CG2 3.71Å; W363-T476 HydrophobicContact CG-CG2 4.34Å; W363-T476 HydrophobicContact CH2-CG2 4.19Å; W363-T476 HydrophobicContact CZ2-CG2 4.3Å; W363-T476 HydrophobicContact CZ3-CG2 3.91Å; G376-T476 CarbonylContact C-O 3.48Å; G376-T476 VanDerWaalsContact CA-O 3.23Å; G376-T476 WeakPolarHBondContact CA-O 3.23Å; C377-T476 PolarHBondContact N-O 3.31Å; I422-T476 HydrophobicContact CG2-CG2 4.14Å; I424-T476 HydrophobicContact CG2-CG2 4.22Å; T476-H478 PolarHBondContact OG1-O 2.93Å; T476-I481 HydrophobicContact CG2-CB 3.95Å; T476-I481 HydrophobicContact CG2-CG2 3.94Å
477Y96.8Very high97.2Very high91 Ų9134.7 Ų34.736%0.35718%0.177SC..SBendtrans-62.3-52.6177.6-173-99.2000111.4C377 N380 P423 Y453C377-Y477 HydrophobicContact CB-CD2 4.26Å; C377-Y477 PolarHBondContact N-O 3.07Å; C377-Y477 PolarHBondContact SG-O 3.47Å; N380-Y477 PolarHBondContact ND2-O 3.16Å; P423-Y477 PolarHBondContact O-N 2.98Å; Y453-Y477 AromaticContact CD1-CD2 3.78Å; Y453-Y477 HydrophobicContact CD1-CD2 3.78Å; Y453-Y477 HydrophobicContact CD1-CG 4.45Å; Y453-Y477 HydrophobicContact CE1-CD2 4.5Å; Y453-Y477 AromaticContact CG-CD2 3.94Å; Y453-Y477 HydrophobicContact CG-CD2 3.94Å
478H96.8Very high97.3Very high115 Ų11530.9 Ų30.953%0.53216%0.159SC..SBendtrans-89.5145.9175.3-61.6-58.8000112.1T476 I481T476-H478 PolarHBondContact OG1-O 2.93Å; H478-I481 HydrophobicContact CB-CG1 4.45Å
479P97.3Very high97.4Very high57 Ų5730.3 Ų30.337%0.3715%0.154SC..THydrogen-bonded Turntrans-70.5162.8173.331-35000111.7N380 I481N380-P479 WeakPolarHBondContact OD1-CD 3.26Å; P479-I481 VanDerWaalsContact C-N 3.25Å; P479-I481 PolarHBondContact O-N 3Å
480G96.6Very high97.3Very high36 Ų3628.4 Ų28.437%0.37115%0.146SC..THydrogen-bonded Turntrans78.5-3.1175.100000115.9S374S374-G480 PolarHBondContact O-N 2.75Å; S374-G480 WeakPolarHBondContact OG-CA 3.26Å
481I95.8Very high97.1Very high58 Ų5828.2 Ų28.230%0.29715%0.146SC..  trans-74.1129.3176-56.4-59.2000110.5W363 S374 I422 T476 H478 P479 T483W363-I481 WeakPolarHBondContact CB-O 3.3Å; S374-I481 VanDerWaalsContact CB-O 3.32Å; S374-I481 WeakPolarHBondContact CB-O 3.36Å; I422-I481 HydrophobicContact CD1-CG2 3.73Å; I422-I481 HydrophobicContact CG2-CG2 4.21Å; T476-I481 HydrophobicContact CG2-CB 3.95Å; T476-I481 HydrophobicContact CG2-CG2 3.94Å; H478-I481 HydrophobicContact CB-CG1 4.45Å; P479-I481 VanDerWaalsContact C-N 3.25Å; P479-I481 PolarHBondContact O-N 3Å; I481-T483 HydrophobicContact CG2-CG2 4.49Å
482I95.9Very high96.6Very high108 Ų10830.2 Ų30.255%0.55416%0.156SC*.  trans-109.1114-178.3-55.8173.7000108.7W363 K365W363-I482 WeakPolarHBondContact O-CA 3.12Å; W363-I482 WeakPolarHBondContact O-CG2 3.29Å; K365-I482 HydrophobicContact CB-CD1 3.64Å; K365-I482 HydrophobicContact CB-CG1 4.02Å
483T95.3Very high96.2Very high12 Ų1232.1 Ų32.17%0.07417%0.168CC..EExtended strand (participates in β ladder)trans-164164.9174.2-171.20000109.9A362 W363 I422 I481A362-T483 WeakPolarHBondContact CA-O 3.28Å; W363-T483 HydrophobicContact CE3-CG2 3.33Å; W363-T483 HydrophobicContact CZ3-CG2 3.52Å; W363-T483 PolarHBondContact N-O 2.77Å; W363-T483 PolarHBondContact O-N 2.66Å; I422-T483 HydrophobicContact CD1-CG2 3.97Å; I481-T483 HydrophobicContact CG2-CG2 4.49Å
484K97.3Very high95.8Very high113 Ų11335.5 Ų35.549%0.49119%0.19SC..EExtended strand (participates in β ladder)trans-91.9157.7175-53.4-179.6-162.61530111.1F128 G361 A362 E408F128-K484 HydrophobicContact CE1-CB 4.1Å; F128-K484 HydrophobicContact CZ-CB 4.03Å; G361-K484 WeakPolarHBondContact O-CA 3.27Å; A362-K484 HydrophobicContact CB-CG 4.2Å; E408-K484 HydrophobicContact CG-CB 3.98Å; E408-K484 IonicContact OE1-NZ 3.31Å
485F97.9Very high95.5Very high0 Ų035.5 Ų35.50%019%0.19CC..EExtended strand (participates in β ladder)trans-141159.4170.863-92.3000111.4F128 G361 W363 P388 Y390 L405 Q406 P474 L487F128-F485 VanDerWaalsContact CZ-CA 3.41Å; G361-F485 PolarHBondContact N-O 2.78Å; G361-F485 PolarHBondContact O-N 2.91Å; G361-F485 VanDerWaalsContact O-O 3.05Å; W363-F485 AromaticContact CD2-CD1 3.67Å; W363-F485 HydrophobicContact CD2-CD1 3.67Å; W363-F485 AromaticContact CD2-CE1 3.97Å; W363-F485 HydrophobicContact CD2-CE1 3.97Å; W363-F485 AromaticContact CE2-CD1 3.67Å; W363-F485 AromaticContact CE2-CE1 3.84Å; W363-F485 AromaticContact CE3-CD1 3.66Å; W363-F485 HydrophobicContact CE3-CD1 3.66Å; W363-F485 HydrophobicContact CE3-CE1 4.4Å; W363-F485 HydrophobicContact CG-CD1 4.44Å; W363-F485 HydrophobicContact CG-CE1 4.33Å; W363-F485 HydrophobicContact CH2-CB 3.82Å; W363-F485 AromaticContact CH2-CD1 3.78Å; W363-F485 HydrophobicContact CH2-CD1 3.78Å; W363-F485 HydrophobicContact CH2-CG 4.02Å; W363-F485 HydrophobicContact CZ2-CB 4.48Å; W363-F485 AromaticContact CZ2-CD1 3.74Å; W363-F485 HydrophobicContact CZ2-CD1 3.74Å; W363-F485 HydrophobicContact CZ2-CE1 4.22Å; W363-F485 HydrophobicContact CZ2-CG 4.2Å; W363-F485 HydrophobicContact CZ3-CB 3.85Å; W363-F485 AromaticContact CZ3-CD1 3.74Å; W363-F485 HydrophobicContact CZ3-CD1 3.74Å; W363-F485 HydrophobicContact CZ3-CG 4.19Å; P388-F485 HydrophobicContact CB-CZ 3.97Å; P388-F485 HydrophobicContact CG-CE1 3.97Å; P388-F485 HydrophobicContact CG-CZ 3.9Å; Y390-F485 AromaticContact CE2-CE2 3.81Å; Y390-F485 HydrophobicContact CE2-CE2 3.81Å; Y390-F485 AromaticContact CE2-CZ 3.85Å; Y390-F485 HydrophobicContact CE2-CZ 3.85Å; Y390-F485 AromaticContact CZ-CE2 3.97Å; Y390-F485 WeakPolarHBondContact OH-CE2 3.39Å; Y390-F485 WeakPolarHBondContact OH-CZ 3.19Å; L405-F485 HydrophobicContact CD1-CB 3.85Å; L405-F485 HydrophobicContact CD1-CD2 3.54Å; L405-F485 HydrophobicContact CD1-CE2 4.33Å; L405-F485 HydrophobicContact CD1-CG 3.85Å; Q406-F485 CarbonylContact O-C 3.58Å; Q406-F485 WeakPolarHBondContact O-CA 3.33Å; Q406-F485 VanDerWaalsContact O-CB 3.3Å; Q406-F485 WeakPolarHBondContact O-CB 3.39Å; P474-F485 HydrophobicContact CB-CE2 4.2Å; P474-F485 HydrophobicContact CB-CZ 4.32Å; P474-F485 HydrophobicContact CG-CD2 4.41Å; P474-F485 HydrophobicContact CG-CE1 4.3Å; P474-F485 HydrophobicContact CG-CE2 3.62Å; P474-F485 HydrophobicContact CG-CZ 3.55Å; F485-L487 HydrophobicContact CD2-CB 4.38Å; F485-L487 HydrophobicContact CE2-CB 4.34Å
486I97.8Very high95.3Very high0 Ų041.8 Ų41.80%022%0.217CC..EExtended strand (participates in β ladder)trans-111.2140.1160.863.5176.5000109.7W126 F128 M359 H360 Q406W126-I486 HydrophobicContact CH2-CD1 3.49Å; W126-I486 VanDerWaalsContact CH2-CD1 3.49Å; W126-I486 HydrophobicContact CZ2-CD1 4.26Å; W126-I486 HydrophobicContact CZ3-CD1 4.25Å; F128-I486 HydrophobicContact CD1-CG2 3.88Å; F128-I486 HydrophobicContact CD2-CD1 4.33Å; F128-I486 HydrophobicContact CD2-CG1 4.2Å; F128-I486 HydrophobicContact CD2-CG2 4.08Å; F128-I486 HydrophobicContact CE1-CG2 3.7Å; F128-I486 HydrophobicContact CE2-CB 4.37Å; F128-I486 HydrophobicContact CE2-CG1 4.1Å; F128-I486 HydrophobicContact CE2-CG2 3.88Å; F128-I486 HydrophobicContact CG-CG2 4.09Å; F128-I486 HydrophobicContact CZ-CG2 3.72Å; F128-I486 WeakPolarHBondContact O-CG2 3.43Å; M359-I486 WeakPolarHBondContact O-CA 3.25Å; H360-I486 WeakPolarHBondContact CD2-CG2 3.22Å; Q406-I486 HydrophobicContact CB-CD1 4.25Å; Q406-I486 HydrophobicContact CB-CG1 3.72Å; Q406-I486 HydrophobicContact CG-CD1 4.41Å; Q406-I486 HydrophobicContact CG-CG1 4.23Å; Q406-I486 PolarHBondContact N-O 2.9Å; Q406-I486 PolarHBondContact O-N 3.24Å
487L97.9Very high95.3Very high0 Ų042.4 Ų42.40%022%0.22CC..EExtended strand (participates in β ladder)trans-116.6119175.317868.4000108.7M358 M359 Y390 V403 L405 L472 F485M358-L487 CarbonylContact C-O 3.51Å; M358-L487 VanDerWaalsContact CA-O 3.31Å; M358-L487 WeakPolarHBondContact CA-O 3.35Å; M359-L487 HydrophobicContact CB-CB 4.4Å; M359-L487 PolarHBondContact N-O 3.42Å; M359-L487 PolarHBondContact O-N 2.86Å; Y390-L487 HydrophobicContact CD1-CD2 4.18Å; Y390-L487 HydrophobicContact CD2-CD2 3.61Å; Y390-L487 HydrophobicContact CE2-CD2 4.11Å; Y390-L487 HydrophobicContact CG-CD2 3.64Å; V403-L487 HydrophobicContact CG1-CD1 3.76Å; L405-L487 HydrophobicContact CD1-CD1 4.5Å; L472-L487 HydrophobicContact CD1-CD1 4.03Å; L472-L487 HydrophobicContact CD1-CD2 4.18Å; L472-L487 HydrophobicContact CD2-CD1 3.77Å; L472-L487 HydrophobicContact CD2-CD2 3.71Å; L472-L487 HydrophobicContact CD2-CG 4.4Å; L472-L487 HydrophobicContact CG-CD2 4.49Å; F485-L487 HydrophobicContact CD2-CB 4.38Å; F485-L487 HydrophobicContact CE2-CB 4.34Å
488R96.8Very high95.4Very high0 Ų042.8 Ų42.80%022%0.221CC..EExtended strand (participates in β ladder)trans-112.2123.3177.2-61.3177.9-69.11741.4109.4G191 A192 K357 M358 V403 S404 F490G191-R488 PolarHBondContact O-NH1 3.14Å; A192-R488 PolarHBondContact O-NH1 3.24Å; K357-R488 CarbonylContact O-C 3.47Å; K357-R488 WeakPolarHBondContact O-CA 3.24Å; M358-R488 HydrophobicContact CB-CG 4.24Å; M358-R488 HydrophobicContact CG-CG 3.85Å; M358-R488 HydrophobicContact SD-CG 4.2Å; V403-R488 WeakPolarHBondContact CA-O 3.41Å; S404-R488 PolarHBondContact N-O 2.55Å; S404-R488 PolarHBondContact O-N 3.36Å; S404-R488 PolarHBondContact OG-NH2 3.38Å; R488-F490 HydrophobicContact CB-CE2 3.7Å; R488-F490 HydrophobicContact CB-CZ 4.16Å
489L96.8Very high95.4Very high0 Ų039.5 Ų39.50%021%0.206CC..EExtended strand (participates in β ladder)trans-113.1134.7175.5-175.171.2000109.5K356 K357 F392 V401 L402 V403 T491 S495 L497K356-L489 WeakPolarHBondContact CA-O 2.91Å; K357-L489 PolarHBondContact N-O 3.05Å; K357-L489 PolarHBondContact O-N 2.87Å; F392-L489 HydrophobicContact CB-CD2 3.76Å; F392-L489 HydrophobicContact CD1-CD2 4.29Å; F392-L489 HydrophobicContact CD2-CD2 3.78Å; F392-L489 HydrophobicContact CE2-CD2 4.44Å; F392-L489 HydrophobicContact CG-CD2 3.68Å; V401-L489 HydrophobicContact CG1-CD1 3.41Å; V401-L489 VanDerWaalsContact CG1-CD1 3.41Å; L402-L489 WeakPolarHBondContact O-CA 3.32Å; V403-L489 HydrophobicContact CG2-CD1 3.75Å; L489-T491 HydrophobicContact CD2-CG2 4.34Å; L489-T491 HydrophobicContact CG-CG2 4.25Å; L489-S495 WeakPolarHBondContact CD2-OG 3.29Å; L489-L497 HydrophobicContact CB-CD2 3.73Å; L489-L497 HydrophobicContact CD2-CB 4.08Å; L489-L497 HydrophobicContact CD2-CD1 4.08Å; L489-L497 HydrophobicContact CD2-CD2 4.22Å; L489-L497 HydrophobicContact CD2-CG 4.36Å
490F94.9Very high95.5Very high3 Ų336.8 Ų36.81%0.01319%0.189CC..EExtended strand (participates in β ladder)trans-125.4127173.9-52.3-99.4000110.6V193 V343 W354 E355 K356 L402 R488V193-F490 HydrophobicContact CG2-CD2 4.41Å; V193-F490 HydrophobicContact CG2-CE1 4.27Å; V193-F490 HydrophobicContact CG2-CE2 3.42Å; V193-F490 VanDerWaalsContact CG2-CE2 3.42Å; V193-F490 HydrophobicContact CG2-CZ 3.32Å; V343-F490 HydrophobicContact CB-CD1 4.18Å; V343-F490 HydrophobicContact CB-CE1 3.89Å; V343-F490 HydrophobicContact CG1-CD1 3.61Å; V343-F490 HydrophobicContact CG1-CE1 3.83Å; V343-F490 HydrophobicContact CG1-CG 4.49Å; V343-F490 HydrophobicContact CG2-CD1 4.3Å; V343-F490 HydrophobicContact CG2-CE1 4Å; V343-F490 HydrophobicContact CG2-CZ 4.38Å; W354-F490 HydrophobicContact CB-CD1 4.42Å; W354-F490 HydrophobicContact CD2-CB 4.35Å; W354-F490 HydrophobicContact CE3-CB 3.75Å; W354-F490 HydrophobicContact CZ3-CB 4.31Å; E355-F490 VanDerWaalsContact O-CA 3.26Å; E355-F490 WeakPolarHBondContact O-CA 3.2Å; K356-F490 HydrophobicContact CB-CD1 3.86Å; K356-F490 HydrophobicContact CB-CE1 3.75Å; K356-F490 HydrophobicContact CD-CE1 3.72Å; K356-F490 HydrophobicContact CD-CZ 4.1Å; K356-F490 HydrophobicContact CG-CD1 4.06Å; K356-F490 HydrophobicContact CG-CE1 3.51Å; K356-F490 HydrophobicContact CG-CZ 3.98Å; L402-F490 HydrophobicContact CB-CB 4.03Å; L402-F490 HydrophobicContact CB-CD2 4.18Å; L402-F490 HydrophobicContact CD1-CB 4.3Å; L402-F490 HydrophobicContact CG-CB 4.31Å; L402-F490 PolarHBondContact N-O 2.79Å; L402-F490 PolarHBondContact O-N 3.41Å; R488-F490 HydrophobicContact CB-CE2 3.7Å; R488-F490 HydrophobicContact CB-CZ 4.16Å
491T93.8Very high95.4Very high0 Ų042.1 Ų42.10%020%0.201CC..EExtended strand (participates in β ladder)trans-135.4164.9178.152.10000110.2E355 V401 L489 V493E355-T491 PolarHBondContact N-O 3.41Å; E355-T491 PolarHBondContact O-N 2.82Å; E355-T491 VanDerWaalsContact O-N 3.14Å; E355-T491 PolarHBondContact OE2-OG1 3.33Å; V401-T491 HydrophobicContact CG1-CG2 4.3Å; V401-T491 HydrophobicContact CG2-CG2 4.15Å; L489-T491 HydrophobicContact CD2-CG2 4.34Å; L489-T491 HydrophobicContact CG-CG2 4.25Å; T491-V493 VanDerWaalsContact C-N 3.3Å; T491-V493 WeakPolarHBondContact CB-O 3.28Å; T491-V493 PolarHBondContact OG1-O 3.25Å
492D88.7Confident95.4Very high41 Ų4140.8 Ų40.822%0.21920%0.199CC..SBendtrans-73.5-27.6178.8-75.53.9000112.4K352 K396 D399K352-D492 WeakPolarHBondContact CE-OD1 3.47Å; K352-D492 IonicContact NZ-OD1 3.14Å; K352-D492 PolarHBondContact NZ-OD1 3.01Å; K352-D492 IonicContact NZ-OD2 3.28Å; K352-D492 PolarHBondContact NZ-OD2 3.14Å; K396-D492 HydrophobicContact CD-CB 4.3Å; K396-D492 IonicContact NZ-OD2 3.25Å; K396-D492 PolarHBondContact NZ-OD2 2.66Å; D399-D492 VanDerWaalsContact OD1-CB 3.24Å; D399-D492 WeakPolarHBondContact OD1-CB 3.47Å; D399-D492 PolarHBondContact OD2-N 3.32Å
493V89.6Confident95.4Very high41 Ų4137 Ų3725%0.24818%0.18CC..SBendtrans-133.2158.8-178.7-66.60000110.4K395 K396 T491 S495K395-V493 HydrophobicContact CB-CG2 4.12Å; K396-V493 HydrophobicContact CG-CG2 4.33Å; T491-V493 VanDerWaalsContact C-N 3.3Å; T491-V493 WeakPolarHBondContact CB-O 3.28Å; T491-V493 PolarHBondContact OG1-O 3.25Å; V493-S495 PolarHBondContact O-N 3.38Å; V493-S495 VanDerWaalsContact O-N 3.12Å
494P91.6Very high95.4Very high71 Ų7140.9 Ų40.946%0.46120%0.196SC..  trans-54.1118.6-178.5-28.735.3000114E355 K395E355-P494 HydrophobicContact CG-CB 4.31Å; E355-P494 HydrophobicContact CG-CG 4.29Å; K395-P494 VanDerWaalsContact CE-O 3.3Å; K395-P494 WeakPolarHBondContact CE-O 3.45Å; K395-P494 PolarHBondContact NZ-O 3.25Å
495S92.5Very high95.2Very high0 Ų036.3 Ų36.30%018%0.178CC..  trans-92.7-8.2-17259.20000114.7E355 D393 L489 V493 L497E355-S495 PolarHBondContact OE2-N 3.5Å; E355-S495 PolarHBondContact OE2-OG 2.87Å; D393-S495 PolarHBondContact N-O 3.22Å; D393-S495 WeakPolarHBondContact O-CA 3.28Å; L489-S495 WeakPolarHBondContact CD2-OG 3.29Å; V493-S495 PolarHBondContact O-N 3.38Å; V493-S495 VanDerWaalsContact O-N 3.12Å; S495-L497 PolarHBondContact O-N 2.98Å
496K94.3Very high94.8Very high131 Ų13144.3 Ų44.357%0.5721%0.213SC*.  trans56.432.6-176.2-57.7-179.2176.6176.50114.1R498K496-R498 PolarHBondContact O-N 2.98Å
497L97.4Very high94.2Very high13 Ų1351.1 Ų51.17%0.06825%0.246CC..  trans-50.9126.9176.3-177.767.1000111.8K357 M359 I391 F392 L489 S495K357-L497 HydrophobicContact CB-CB 3.86Å; K357-L497 HydrophobicContact CB-CD2 3.7Å; K357-L497 HydrophobicContact CB-CG 4.38Å; K357-L497 HydrophobicContact CG-CB 4.12Å; M359-L497 HydrophobicContact CG-CD2 3.59Å; M359-L497 HydrophobicContact CG-CG 3.98Å; I391-L497 VanDerWaalsContact O-CA 3.3Å; I391-L497 WeakPolarHBondContact O-CA 3.39Å; F392-L497 HydrophobicContact CB-CB 4.38Å; F392-L497 HydrophobicContact CB-CD1 3.99Å; L489-L497 HydrophobicContact CB-CD2 3.73Å; L489-L497 HydrophobicContact CD2-CB 4.08Å; L489-L497 HydrophobicContact CD2-CD1 4.08Å; L489-L497 HydrophobicContact CD2-CD2 4.22Å; L489-L497 HydrophobicContact CD2-CG 4.36Å; S495-L497 PolarHBondContact O-N 2.98Å
498R97.6Very high93.5Very high99 Ų9954.7 Ų54.737%0.37427%0.268SS..EExtended strand (participates in β ladder)trans-155.8158.3173.765.1-178.7-179.883-1111.6Y390 I391 K496Y390-R498 CarbonylContact C-O 3.52Å; Y390-R498 WeakPolarHBondContact CA-O 3.4Å; I391-R498 HydrophobicContact CG2-CG 3.56Å; I391-R498 PolarHBondContact N-O 3.27Å; I391-R498 PolarHBondContact O-N 3.49Å; K496-R498 PolarHBondContact O-N 2.98Å
499E98.3Very high92.6Very high46 Ų4659.1 Ų59.122%0.21530%0.298CS..EExtended strand (participates in β ladder)trans-76.2140.5173.2-165.2-173.4165.700111.7M359 Q389 Y390 K501M359-E499 HydrophobicContact CE-CB 4.47Å; Q389-E499 CarbonylContact O-C 3.57Å; Q389-E499 WeakPolarHBondContact O-CA 3.41Å; Y390-E499 HydrophobicContact CD1-CB 3.98Å; Y390-E499 HydrophobicContact CD1-CG 4.35Å; Y390-E499 HydrophobicContact CE1-CB 3.81Å; Y390-E499 HydrophobicContact CE1-CG 4Å; E499-K501 HydrophobicContact CB-CG 4.29Å; E499-K501 HydrophobicContact CG-CG 4.07Å; E499-K501 PolarHBondContact O-N 3.35Å; E499-K501 WeakPolarHBondContact OE2-CE 3.35Å; E499-K501 IonicContact OE2-NZ 3.73Å
500L97.9Very high91.6Very high1 Ų167.1 Ų67.11%0.00533%0.328CS..  trans-87.498.1166.8-64.8176000109Q389 I391 S436 R438 V471Q389-L500 HydrophobicContact CB-CB 4.19Å; Q389-L500 HydrophobicContact CB-CD1 4.31Å; Q389-L500 PolarHBondContact O-N 3.13Å; I391-L500 HydrophobicContact CB-CD1 4.06Å; I391-L500 HydrophobicContact CB-CD2 4.03Å; I391-L500 HydrophobicContact CB-CG 3.93Å; I391-L500 HydrophobicContact CD1-CD1 4.27Å; I391-L500 HydrophobicContact CD1-CD2 4.15Å; I391-L500 HydrophobicContact CG2-CD2 3.76Å; I391-L500 HydrophobicContact CG2-CG 4.08Å; S436-L500 WeakPolarHBondContact O-CD2 3.45Å; R438-L500 VanDerWaalsContact CD-O 3.28Å; R438-L500 WeakPolarHBondContact CD-O 3.41Å; R438-L500 HydrophobicContact CG-CB 3.84Å; R438-L500 WeakPolarHBondContact CG-O 3.26Å; R438-L500 PolarHBondContact NH1-O 2.81Å; V471-L500 HydrophobicContact CG2-CD1 3.87Å
501K95.3Very high90.9Very high147 Ų14767.9 Ų67.964%0.63933%0.334SS*.  trans-92.9-31.5-178.9-66.2-172.6174.4-173.60114.3E499E499-K501 HydrophobicContact CB-CG 4.29Å; E499-K501 HydrophobicContact CG-CG 4.07Å; E499-K501 PolarHBondContact O-N 3.35Å; E499-K501 WeakPolarHBondContact OE2-CE 3.35Å; E499-K501 IonicContact OE2-NZ 3.73Å
502A96.4Very high89.9Confident31 Ų3175.1 Ų75.126%0.25637%0.372SS..  trans-95133.2-175.700000111.1Y437 R438Y437-A502 WeakPolarHBondContact CA-O 3.47Å; Y437-A502 WeakPolarHBondContact CB-O 3.46Å; Y437-A502 HydrophobicContact CD1-CB 3.93Å; Y437-A502 HydrophobicContact CE1-CB 4.38Å; R438-A502 PolarHBondContact N-O 3.01Å
503D95.6Very high89.3Confident29 Ų2979.7 Ų79.716%0.15540%0.395CS..SBendtrans-78.8-28.4178.9-54.4-77.3000113R438 H440 V642R438-D503 VanDerWaalsContact CD-OD1 3.24Å; R438-D503 WeakPolarHBondContact CD-OD1 3.39Å; R438-D503 IonicContact NE-OD1 3.5Å; R438-D503 PolarHBondContact NE-OD1 2.96Å; H440-D503 IonicContact CE1-OD1 3.26Å; H440-D503 PolarHBondContact CE1-OD1 3.19Å; H440-D503 VanDerWaalsContact CE1-OD1 3.27Å; H440-D503 PolarHBondContact NE2-O 3.22Å; D503-V642 HydrophobicContact CB-CG1 3.88Å
504K94.4Very high88.8Confident92 Ų9281.5 Ų81.540%0.441%0.409SS..SBendtrans-155.9168.4-178.462-179.8171.8-170.10111.3Y437 K506 Y573 L641 V642Y437-K504 VanDerWaalsContact CD1-C 3.47Å; Y437-K504 VanDerWaalsContact CE1-C 3.45Å; Y437-K504 WeakPolarHBondContact CE1-O 3.46Å; K504-K506 PolarHBondContact O-N 3.38Å; K504-Y573 HydrophobicContact CB-CE1 4.25Å; K504-L641 HydrophobicContact CB-CB 4.14Å; K504-L641 HydrophobicContact CD-CB 3.97Å; K504-L641 HydrophobicContact CD-CD1 4.23Å; K504-V642 HydrophobicContact CB-CG1 4.25Å; K504-V642 HydrophobicContact CD-CG1 4.04Å; K504-V642 HydrophobicContact CG-CG1 4.31Å
505P93.6Very high88.6Confident17 Ų1779.7 Ų79.711%0.1140%0.403CS..PPolyproline II helixtrans-51.7132.1172.6-26.332.3000112.1Y437 Y516 P517 Y573Y437-P505 HydrophobicContact CE1-CG 4.33Å; Y437-P505 HydrophobicContact CE2-CG 3.68Å; Y437-P505 WeakPolarHBondContact OH-CA 3.19Å; Y437-P505 WeakPolarHBondContact OH-CG 3.39Å; P505-Y516 HydrophobicContact CB-CE2 4.46Å; P505-Y516 WeakPolarHBondContact O-CE2 3.48Å; P505-Y516 PolarHBondContact O-OH 3.07Å; P505-P517 HydrophobicContact CB-CG 4.35Å; P505-P517 HydrophobicContact CG-CG 4.18Å; P505-Y573 HydrophobicContact CG-CD1 3.55Å; P505-Y573 HydrophobicContact CG-CD2 4.31Å; P505-Y573 HydrophobicContact CG-CE1 4.1Å; P505-Y573 HydrophobicContact CG-CG 3.64Å
506K89.1Confident88.5Confident168 Ų16882.5 Ų82.573%0.7341%0.414SS*.PPolyproline II helixtrans-71.6138.7176.6-68.4-171.5177.9-173.60110.2K504K504-K506 PolarHBondContact O-N 3.38Å
507M86.1Confident88.5Confident144 Ų14476.8 Ų76.871%0.70939%0.391SS*.PPolyproline II helixtrans-71.1130.3168.7-160.5159.77100108.5Y516M507-Y516 HydrophobicContact CB-CD2 4.33Å; M507-Y516 HydrophobicContact CB-CE2 4.16Å; M507-Y516 HydrophobicContact CG-CD2 4.23Å
508T83.6Confident88.3Confident74 Ų7484 Ų8445%0.45442%0.417SS..  trans-127.7167.9179.460.80000109.4W510 S511T508-W510 PolarHBondContact O-N 3.14Å; T508-S511 PolarHBondContact N-OG 3.19Å; T508-S511 WeakPolarHBondContact O-CA 3.05Å; T508-S511 WeakPolarHBondContact O-CB 3.48Å; T508-S511 PolarHBondContact O-N 3.23Å; T508-S511 PolarHBondContact O-OG 3.46Å; T508-S511 PolarHBondContact OG1-OG 2.99Å
509C78.3Confident88.2Confident93 Ų9380.4 Ų80.463%0.62840%0.404SS*.Hα-helixtrans-56.1-34.4174.152.40000112.5S511 L512C509-S511 PolarHBondContact O-N 3.34Å; C509-L512 WeakPolarHBondContact O-CB 3.5Å; C509-L512 PolarHBondContact O-N 3Å
510W75Confident88.1Confident169 Ų16978.2 Ų78.264%0.6439%0.393SS*.Hα-helixtrans-66.8-21.3173.4-65.8103.4000114T508 L512 L513 C514T508-W510 PolarHBondContact O-N 3.14Å; W510-L512 PolarHBondContact O-N 3.48Å; W510-L513 HydrophobicContact CE3-CD1 4.05Å; W510-L513 HydrophobicContact CZ3-CD1 4.15Å; W510-L513 PolarHBondContact O-N 3.09Å; W510-C514 WeakPolarHBondContact O-CB 3.48Å; W510-C514 PolarHBondContact O-N 3.08Å
511S80.8Confident88Confident18 Ų1878.2 Ų78.213%0.12639%0.393CS..Hα-helixtrans-67.1-25175.2-54.30000112.3T508 C509 G515T508-S511 PolarHBondContact N-OG 3.19Å; T508-S511 WeakPolarHBondContact O-CA 3.05Å; T508-S511 WeakPolarHBondContact O-CB 3.48Å; T508-S511 PolarHBondContact O-N 3.23Å; T508-S511 PolarHBondContact O-OG 3.46Å; T508-S511 PolarHBondContact OG1-OG 2.99Å; C509-S511 PolarHBondContact O-N 3.34Å; S511-G515 CarbonylContact O-C 3.17Å; S511-G515 WeakPolarHBondContact O-CA 3.12Å; S511-G515 PolarHBondContact O-N 3.21Å; S511-G515 VanDerWaalsContact O-N 3.09Å
512L72.3Confident88Confident153 Ų15371.2 Ų71.280%0.80136%0.363SS*.Hα-helixtrans-72.1-34.4174.7-65.9164.4000111.8C509 W510C509-L512 WeakPolarHBondContact O-CB 3.5Å; C509-L512 PolarHBondContact O-N 3Å; W510-L512 PolarHBondContact O-N 3.48Å
513L76.4Confident88Confident136 Ų13669.7 Ų69.771%0.71235%0.35SS*.Hα-helixtrans-87.2-38.4-178.6-67.6169.3000112.8W510W510-L513 HydrophobicContact CE3-CD1 4.05Å; W510-L513 HydrophobicContact CZ3-CD1 4.15Å; W510-L513 PolarHBondContact O-N 3.09Å
514C79.3Confident88Confident79 Ų7969.8 Ų69.853%0.53435%0.349SS..Hα-helixtrans-110.411.6-172.2-56.70000113.3W510 K575W510-C514 WeakPolarHBondContact O-CB 3.48Å; W510-C514 PolarHBondContact O-N 3.08Å; C514-K575 WeakPolarHBondContact O-CD 3.33Å; C514-K575 PolarHBondContact O-NZ 3.43Å
515G85.6Confident88Confident33 Ų3365.4 Ų65.434%0.3433%0.33SS..  trans73.3158.1-176.300000114.8S511 K575S511-G515 CarbonylContact O-C 3.17Å; S511-G515 WeakPolarHBondContact O-CA 3.12Å; S511-G515 PolarHBondContact O-N 3.21Å; S511-G515 VanDerWaalsContact O-N 3.09Å; G515-K575 WeakPolarHBondContact O-CE 3.23Å; G515-K575 PolarHBondContact O-NZ 3.38Å
516Y91.8Very high88Confident59 Ų5966.7 Ų66.723%0.23134%0.335CS..  trans-109.6146.5174.8-173.8-104.9000110.5P505 M507 R518 L641P505-Y516 HydrophobicContact CB-CE2 4.46Å; P505-Y516 WeakPolarHBondContact O-CE2 3.48Å; P505-Y516 PolarHBondContact O-OH 3.07Å; M507-Y516 HydrophobicContact CB-CD2 4.33Å; M507-Y516 HydrophobicContact CB-CE2 4.16Å; M507-Y516 HydrophobicContact CG-CD2 4.23Å; Y516-R518 PolarHBondContact O-N 3.44Å; Y516-L641 HydrophobicContact CD1-CD1 4.48Å; Y516-L641 HydrophobicContact CE1-CD1 3.56Å
517P93.6Very high88.3Confident12 Ų1259.3 Ų59.38%0.07830%0.304CS..  trans-55.7139.6175.7-28.338.2000112.4P505 R574 K575 L641P505-P517 HydrophobicContact CB-CG 4.35Å; P505-P517 HydrophobicContact CG-CG 4.18Å; P517-R574 CarbonylContact C-O 3.55Å; P517-R574 VanDerWaalsContact CA-O 3.3Å; P517-R574 WeakPolarHBondContact CA-O 3.5Å; P517-K575 HydrophobicContact CG-CG 4.25Å; P517-L641 HydrophobicContact CB-CD1 4.13Å; P517-L641 HydrophobicContact CB-CD2 4.35Å; P517-L641 WeakPolarHBondContact O-CD1 3.06Å
518R94.2Very high88.8Confident164 Ų16452.4 Ų52.462%0.61927%0.27SS*.  trans-119.8-14.1-179.9-63.5178.364.6-169.5-0.3112.9Y516 R574 I577Y516-R518 PolarHBondContact O-N 3.44Å; R518-R574 PolarHBondContact N-O 3.02Å; R518-I577 HydrophobicContact CB-CG2 4.23Å
519R95.1Very high89.3Confident24 Ų2453.5 Ų53.59%0.09127%0.27CS..EExtended strand (participates in β ladder)trans-143.3138.4-178.9-179.5168.3-66.1166.74.1110.2Y573 R574 I577 S638 D639R519-Y573 CarbonylContact O-C 3.58Å; R519-R574 HydrophobicContact CB-CB 4.39Å; R519-R574 PolarHBondContact N-O 2.74Å; R519-R574 PolarHBondContact O-N 3.17Å; R519-I577 HydrophobicContact CB-CG2 4.05Å; R519-S638 CarbonylContact C-O 3.52Å; R519-S638 VanDerWaalsContact CA-O 3.31Å; R519-S638 WeakPolarHBondContact CA-O 3.48Å; R519-S638 WeakPolarHBondContact CG-O 3.26Å; R519-D639 IonicContact CZ-OD1 2.8Å; R519-D639 VanDerWaalsContact CZ-OD1 3.24Å; R519-D639 IonicContact NE-OD1 3.75Å; R519-D639 PolarHBondContact NE-OD1 2.84Å; R519-D639 IonicContact NH2-OD1 3.88Å; R519-D639 PolarHBondContact NH2-OD1 2.85Å; R519-D639 IonicContact NH2-OD2 3.19Å; R519-D639 PolarHBondContact NH2-OD2 2.98Å
520V95.9Very high90Very high0 Ų051.3 Ų51.30%026%0.263CS..EExtended strand (participates in β ladder)trans-104.4132.516759.50000108.4I571 F572 Y573 S637 S638 D640 L641 L644V520-I571 HydrophobicContact CG2-CD1 3.72Å; V520-I571 HydrophobicContact CG2-CG1 3.75Å; V520-F572 CarbonylContact C-O 3.55Å; V520-F572 WeakPolarHBondContact CA-O 3.41Å; V520-Y573 HydrophobicContact CB-CD1 4.34Å; V520-Y573 HydrophobicContact CB-CE1 4.29Å; V520-Y573 HydrophobicContact CG2-CD1 4.37Å; V520-Y573 HydrophobicContact CG2-CD2 4.5Å; V520-Y573 HydrophobicContact CG2-CE1 4.1Å; V520-Y573 HydrophobicContact CG2-CE2 4.19Å; V520-S637 CarbonylContact O-C 3.51Å; V520-S637 VanDerWaalsContact O-CA 3.27Å; V520-S637 WeakPolarHBondContact O-CA 3.48Å; V520-S638 PolarHBondContact N-O 2.81Å; V520-S638 PolarHBondContact O-N 3.27Å; V520-D640 VanDerWaalsContact CG1-O 3.32Å; V520-D640 WeakPolarHBondContact CG1-O 3.49Å; V520-L641 HydrophobicContact CB-CD2 4.27Å; V520-L644 HydrophobicContact CG1-CB 4.05Å; V520-L644 HydrophobicContact CG1-CD1 3.9Å; V520-L644 HydrophobicContact CG1-CG 3.93Å; V520-L644 HydrophobicContact CG2-CB 4.15Å; V520-L644 HydrophobicContact CG2-CD1 4.32Å
521T95.8Very high90.9Very high0 Ų043.6 Ų43.60%024%0.235CC..EExtended strand (participates in β ladder)trans-128.6123.9177.2-61.30000110.2I571 F572 R574 I581 A603 V635 F636 S637T521-I571 CarbonylContact O-C 3.47Å; T521-I571 WeakPolarHBondContact O-CA 3.23Å; T521-F572 PolarHBondContact N-O 3.19Å; T521-F572 PolarHBondContact O-N 2.78Å; T521-R574 WeakPolarHBondContact OG1-CD 3.5Å; T521-R574 PolarHBondContact OG1-NH1 3.15Å; T521-I581 HydrophobicContact CG2-CD1 3.3Å; T521-A603 HydrophobicContact CG2-CB 3.75Å; T521-V635 HydrophobicContact CG2-CG1 3.83Å; T521-F636 CarbonylContact C-O 3.57Å; T521-F636 VanDerWaalsContact CA-O 3.25Å; T521-F636 WeakPolarHBondContact CA-O 3.41Å; T521-S637 WeakPolarHBondContact CB-OG 3.44Å; T521-S637 VanDerWaalsContact CG2-OG 3.25Å; T521-S637 WeakPolarHBondContact CG2-OG 3.41Å; T521-S637 PolarHBondContact OG1-OG 3.11Å
522Q95.8Very high91.2Very high0 Ų047.4 Ų47.40%025%0.25CS..EExtended strand (participates in β ladder)trans-97.3141.7166.6-71.8171.3-35.800110.3E432 T443 V444 Q445 A570 I571 V635 F636 L644E432-Q522 VanDerWaalsContact OE1-CD 3.31Å; E432-Q522 VanDerWaalsContact OE1-CG 3.31Å; E432-Q522 WeakPolarHBondContact OE1-CG 3.26Å; E432-Q522 PolarHBondContact OE1-NE2 2.94Å; T443-Q522 PolarHBondContact OG1-OE1 2.97Å; V444-Q522 HydrophobicContact CG2-CB 4.5Å; Q445-Q522 VanDerWaalsContact NE2-NE2 3.11Å; Q522-A570 CarbonylContact C-O 3.5Å; Q522-A570 WeakPolarHBondContact CA-O 3.29Å; Q522-I571 HydrophobicContact CG-CB 4.24Å; Q522-I571 HydrophobicContact CG-CD1 3.94Å; Q522-I571 HydrophobicContact CG-CG1 3.98Å; Q522-V635 WeakPolarHBondContact O-CA 3.37Å; Q522-F636 HydrophobicContact CB-CB 4.36Å; Q522-F636 PolarHBondContact N-O 3.31Å; Q522-F636 PolarHBondContact O-N 3.22Å; Q522-L644 HydrophobicContact CB-CD1 4.38Å; Q522-L644 HydrophobicContact CG-CB 4.15Å; Q522-L644 HydrophobicContact CG-CD1 4.02Å; Q522-L644 PolarHBondContact NE2-OXT 3.21Å
523I95.4Very high91.8Very high0 Ų046.6 Ų46.60%024%0.24CC..EExtended strand (participates in β ladder)trans-136.8132.3174.4-178.2170.3000110I525 I546 Q569 A570 F572 I581 V583 L601 K634 V635I523-I525 HydrophobicContact CD1-CD1 3.69Å; I523-I525 HydrophobicContact CG1-CD1 3.81Å; I523-I546 HydrophobicContact CD1-CG2 4.42Å; I523-I546 HydrophobicContact CG2-CD1 4.14Å; I523-I546 HydrophobicContact CG2-CG2 3.96Å; I523-Q569 CarbonylContact O-C 3.39Å; I523-Q569 VanDerWaalsContact O-CA 3.3Å; I523-Q569 WeakPolarHBondContact O-CA 3.33Å; I523-A570 HydrophobicContact CG2-CB 3.81Å; I523-A570 PolarHBondContact N-O 3.29Å; I523-A570 PolarHBondContact O-N 3.13Å; I523-F572 HydrophobicContact CG2-CD2 4.48Å; I523-F572 HydrophobicContact CG2-CE2 3.99Å; I523-I581 HydrophobicContact CD1-CG2 4.28Å; I523-V583 HydrophobicContact CD1-CG2 3.6Å; I523-L601 HydrophobicContact CD1-CD1 3.37Å; I523-K634 CarbonylContact C-O 3.59Å; I523-K634 WeakPolarHBondContact CA-O 3.44Å; I523-V635 HydrophobicContact CD1-CG2 4.28Å; I523-V635 HydrophobicContact CG1-CG2 4.16Å
524K95.2Very high92.1Very high30 Ų3042.5 Ų42.513%0.1322%0.218CC..EExtended strand (participates in β ladder)trans-114.5127.3168.6-180166.5-172.4166.10108.8V444 D567 Q569 V633 K634V444-K524 HydrophobicContact CB-CB 4.28Å; V444-K524 HydrophobicContact CB-CD 4.38Å; V444-K524 HydrophobicContact CG1-CB 4.23Å; K524-D567 IonicContact NZ-OD1 2.89Å; K524-Q569 HydrophobicContact CB-CG 4.18Å; K524-Q569 HydrophobicContact CD-CG 4.15Å; K524-Q569 HydrophobicContact CG-CG 3.94Å; K524-V633 CarbonylContact O-C 3.59Å; K524-V633 WeakPolarHBondContact O-CA 3.45Å; K524-K634 HydrophobicContact CB-CB 4.45Å; K524-K634 PolarHBondContact N-O 2.97Å; K524-K634 PolarHBondContact O-N 2.85Å
525I95.3Very high91.9Very high0 Ų042.1 Ų42.10%021%0.21CC..EExtended strand (participates in β ladder)trans-94.9126.3172.3-48.3-59.2000107.2I523 V544 I546 F566 T568 V583 I631 V633I523-I525 HydrophobicContact CD1-CD1 3.69Å; I523-I525 HydrophobicContact CG1-CD1 3.81Å; I525-V544 HydrophobicContact CG1-CG1 4.17Å; I525-V544 HydrophobicContact CG2-CG1 4.46Å; I525-V544 HydrophobicContact CG2-CG2 4.26Å; I525-I546 HydrophobicContact CD1-CD1 4.04Å; I525-I546 HydrophobicContact CD1-CG1 4.36Å; I525-I546 HydrophobicContact CG1-CD1 3.59Å; I525-I546 HydrophobicContact CG1-CG1 4.14Å; I525-F566 HydrophobicContact CB-CB 4.24Å; I525-F566 HydrophobicContact CG2-CB 4.02Å; I525-F566 HydrophobicContact CG2-CD2 3.95Å; I525-F566 HydrophobicContact CG2-CG 4.28Å; I525-F566 CarbonylContact O-C 3.59Å; I525-T568 PolarHBondContact N-O 3.42Å; I525-V583 HydrophobicContact CD1-CG1 3.73Å; I525-V583 HydrophobicContact CD1-CG2 4.11Å; I525-I631 HydrophobicContact CG2-CD1 3.98Å; I525-I631 HydrophobicContact CG2-CG1 4.14Å; I525-V633 HydrophobicContact CD1-CB 4.26Å; I525-V633 HydrophobicContact CD1-CG1 3.49Å; I525-V633 VanDerWaalsContact CD1-CG1 3.49Å
526H93.4Very high91Very high45 Ų4553.3 Ų53.321%0.20824%0.242CC..EExtended strand (participates in β ladder)trans-97.5-55.7-178-73.8-93.2000111.9V565 F566 T632H526-V565 WeakPolarHBondContact O-CA 3.41Å; H526-V565 WeakPolarHBondContact O-CG1 3.47Å; H526-F566 PolarHBondContact O-N 3.01Å; H526-F566 VanDerWaalsContact O-O 3.08Å; H526-T632 HydrophobicContact CB-CG2 4.27Å; H526-T632 PolarHBondContact N-O 3.44Å
527S95.6Very high89.8Confident12 Ų1255.1 Ų55.18%0.08426%0.263CS..EExtended strand (participates in β ladder)trans-151.3159.9-177.963.20000111.7E529 A564 I631 T632S527-E529 PolarHBondContact OG-OE1 2.98Å; S527-A564 CarbonylContact C-O 3.53Å; S527-A564 WeakPolarHBondContact CA-O 3.49Å; S527-A564 WeakPolarHBondContact CB-O 3.45Å; S527-I631 WeakPolarHBondContact O-CA 3.31Å; S527-I631 WeakPolarHBondContact O-CG1 3.2Å; S527-T632 PolarHBondContact N-O 3.17Å; S527-T632 PolarHBondContact O-N 2.78Å; S527-T632 PolarHBondContact OG-OG1 2.99Å
528A95.8Very high88.5Confident0 Ų055.4 Ų55.40%027%0.269CS..EExtended strand (participates in β ladder)trans-129.1130.6157.300000109.4L531 S563 A564 F566 V585 R630 I631A528-L531 HydrophobicContact CB-CD1 4.21Å; A528-L531 HydrophobicContact CB-CD2 4.12Å; A528-L531 HydrophobicContact CB-CG 4.4Å; A528-S563 CarbonylContact O-C 3.43Å; A528-S563 WeakPolarHBondContact O-CA 3.26Å; A528-A564 PolarHBondContact N-O 3.23Å; A528-A564 PolarHBondContact O-N 2.9Å; A528-F566 HydrophobicContact CB-CE2 3.77Å; A528-V585 HydrophobicContact CB-CG2 4.41Å; A528-R630 CarbonylContact C-O 3.54Å; A528-R630 WeakPolarHBondContact CA-O 3.2Å; A528-I631 HydrophobicContact CB-CG1 4.39Å
529E95.4Very high87.9Confident97 Ų9747.8 Ų47.845%0.45324%0.242SC..EExtended strand (participates in β ladder)trans-130149.9-168-69.9163.8-142.800110.9S527 L531 G629 R630S527-E529 PolarHBondContact OG-OE1 2.98Å; E529-L531 VanDerWaalsContact C-N 3.29Å; E529-L531 PolarHBondContact O-N 3.32Å; E529-G629 CarbonylContact O-C 3.49Å; E529-G629 WeakPolarHBondContact O-CA 3.33Å; E529-R630 PolarHBondContact N-O 2.99Å; E529-R630 PolarHBondContact O-N 3.21Å
530G93.1Very high87.5Confident47 Ų4746.9 Ų46.949%0.48524%0.239SC..SBendtrans68.528.4178.700000113.4T562 P628 G629G530-T562 PolarHBondContact N-O 2.84Å; G530-P628 CarbonylContact O-C 3.58Å; G530-G629 WeakPolarHBondContact O-CA 3.26Å; G530-G629 PolarHBondContact O-N 3.27Å; G530-G629 VanDerWaalsContact O-N 3.1Å
531L92.6Very high87.4Confident7 Ų749.6 Ų49.64%0.03725%0.254CS..PPolyproline II helixtrans-65.2150.3179.8-61.4175.9000111.6A528 E529 K533 P542 T562 V585 L596 L616A528-L531 HydrophobicContact CB-CD1 4.21Å; A528-L531 HydrophobicContact CB-CD2 4.12Å; A528-L531 HydrophobicContact CB-CG 4.4Å; E529-L531 VanDerWaalsContact C-N 3.29Å; E529-L531 PolarHBondContact O-N 3.32Å; L531-K533 PolarHBondContact O-N 3.25Å; L531-P542 HydrophobicContact CD1-CB 3.54Å; L531-P542 HydrophobicContact CD1-CG 3.82Å; L531-T562 WeakPolarHBondContact CB-O 3.3Å; L531-T562 WeakPolarHBondContact CG-O 3.41Å; L531-T562 PolarHBondContact N-O 3.31Å; L531-T562 WeakPolarHBondContact O-CG2 3.34Å; L531-V585 HydrophobicContact CD1-CG1 4.12Å; L531-V585 HydrophobicContact CD2-CG1 3.98Å; L531-L596 HydrophobicContact CB-CD1 4.46Å; L531-L596 HydrophobicContact CD1-CD1 4.3Å; L531-L616 HydrophobicContact CD2-CD1 3.66Å
532Q88.8Confident87.4Confident97 Ų9749.6 Ų49.645%0.45325%0.254SS..PPolyproline II helixtrans-64.4126.6176.5-171.4178.919.400110.8Q534 P628Q532-Q534 PolarHBondContact O-NE2 3.39Å; Q532-P628 HydrophobicContact CB-CB 4.18Å; Q532-P628 HydrophobicContact CB-CG 4.33Å
533K84.9Confident87.4Confident136 Ų13650.1 Ų50.159%0.59126%0.256SS*.PPolyproline II helixtrans-60.7138.4174.3-58.6-177167.6-171.90110.9L531 G538 T562L531-K533 PolarHBondContact O-N 3.25Å; K533-G538 WeakPolarHBondContact CD-O 3.36Å; K533-G538 WeakPolarHBondContact CE-O 3.41Å; K533-G538 VanDerWaalsContact CG-O 3.26Å; K533-G538 WeakPolarHBondContact CG-O 3.25Å; K533-T562 HydrophobicContact CG-CG2 3.95Å
534Q82.6Confident87.5Confident51 Ų5150.1 Ų50.124%0.23826%0.256CS..  trans-117.8-28.1-175.5-60.4-53.9-38.600113.9Q532 G539 A540 N587 L596Q532-Q534 PolarHBondContact O-NE2 3.39Å; Q534-G539 PolarHBondContact N-O 2.77Å; Q534-A540 HydrophobicContact CG-CB 4.17Å; Q534-N587 HydrophobicContact CG-CB 4.07Å; Q534-L596 HydrophobicContact CG-CD2 4.17Å
535D73.3Confident87.6Confident70 Ų7049.7 Ų49.737%0.37426%0.255SS..SBendtrans-107.2174.1-179.770.312.7000113.1S537 G538 G539D535-S537 VanDerWaalsContact C-N 3.27Å; D535-S537 PolarHBondContact O-N 2.94Å; D535-S537 PolarHBondContact OD1-N 2.94Å; D535-S537 PolarHBondContact OD1-OG 2.73Å; D535-S537 VanDerWaalsContact OD1-OG 3.09Å; D535-S537 PolarHBondContact OD2-OG 3.5Å; D535-G538 PolarHBondContact O-N 3.33Å; D535-G538 PolarHBondContact OD1-N 2.96Å; D535-G539 PolarHBondContact N-O 2.8Å; D535-G539 PolarHBondContact OD1-N 2.99Å
536R68.1Low87.7Confident268 Ų26849.7 Ų49.7100%1.01126%0.255SS*.THydrogen-bonded Turntrans-71.5-21.7178.3-66.9-176.6179.8-177.3-0.1112.9G538R536-G538 VanDerWaalsContact C-N 3.27Å
537S65.4Low87.8Confident97 Ų9750.6 Ų50.668%0.67826%0.258SS*.THydrogen-bonded Turntrans-73.6-18.7173.57.70000112.4D535D535-S537 VanDerWaalsContact C-N 3.27Å; D535-S537 PolarHBondContact O-N 2.94Å; D535-S537 PolarHBondContact OD1-N 2.94Å; D535-S537 PolarHBondContact OD1-OG 2.73Å; D535-S537 VanDerWaalsContact OD1-OG 3.09Å; D535-S537 PolarHBondContact OD2-OG 3.5Å
538G67.8Low87.8Confident19 Ų1950.2 Ų50.220%0.19626%0.255CS..SBendtrans87.617.2-178.600000114.5K533 D535 R536K533-G538 WeakPolarHBondContact CD-O 3.36Å; K533-G538 WeakPolarHBondContact CE-O 3.41Å; K533-G538 VanDerWaalsContact CG-O 3.26Å; K533-G538 WeakPolarHBondContact CG-O 3.25Å; D535-G538 PolarHBondContact O-N 3.33Å; D535-G538 PolarHBondContact OD1-N 2.96Å; R536-G538 VanDerWaalsContact C-N 3.27Å
539G80.2Confident87.6Confident4 Ų453.5 Ų53.54%0.04127%0.27CS..  trans-100.6179.8174.100000114.1Q534 D535 D560Q534-G539 PolarHBondContact N-O 2.77Å; D535-G539 PolarHBondContact N-O 2.8Å; D535-G539 PolarHBondContact OD1-N 2.99Å; G539-D560 WeakPolarHBondContact CA-OD1 3.48Å
540A87.7Confident87.3Confident4 Ų457.1 Ų57.13%0.03329%0.293CS..  trans-151.9157.6175.400000108.7Q534 P542 D560 T561 N587Q534-A540 HydrophobicContact CG-CB 4.17Å; A540-P542 WeakPolarHBondContact O-CD 3.17Å; A540-D560 CarbonylContact O-C 3.16Å; A540-D560 WeakPolarHBondContact O-CA 3.3Å; A540-D560 PolarHBondContact O-N 2.9Å; A540-T561 PolarHBondContact O-N 3.44Å; A540-N587 WeakPolarHBondContact CA-OD1 3.39Å; A540-N587 WeakPolarHBondContact CB-OD1 3.29Å
541D93.5Very high87.3Confident58 Ų5859.3 Ų59.331%0.3129%0.291SS..  trans-11069176-69.4-31.2000111.1V557 Q558 Q559 D560 N587 S588D541-V557 HydrophobicContact CB-CG1 3.83Å; D541-Q558 CarbonylContact C-O 3.54Å; D541-Q558 VanDerWaalsContact C-O 3.26Å; D541-Q558 WeakPolarHBondContact CA-O 3.43Å; D541-Q559 VanDerWaalsContact OD1-CA 3.31Å; D541-Q559 WeakPolarHBondContact OD1-CA 3.35Å; D541-D560 PolarHBondContact OD1-N 2.64Å; D541-N587 PolarHBondContact N-OD1 3.34Å; D541-S588 PolarHBondContact O-N 3.31Å
542P95Very high87.5Confident0 Ų066.7 Ų66.70%032%0.322CS..EExtended strand (participates in β ladder)trans-75.5143.2-168.631.4-38.9000113.7L531 A540 Q558 T561 A564 F566 V585 W586 L596L531-P542 HydrophobicContact CD1-CB 3.54Å; L531-P542 HydrophobicContact CD1-CG 3.82Å; A540-P542 WeakPolarHBondContact O-CD 3.17Å; P542-Q558 VanDerWaalsContact CD-O 3.25Å; P542-Q558 WeakPolarHBondContact CD-O 3.22Å; P542-Q558 HydrophobicContact CG-CB 4.28Å; P542-Q558 PolarHBondContact O-N 2.91Å; P542-T561 VanDerWaalsContact CD-O 3.27Å; P542-T561 WeakPolarHBondContact CD-O 3.36Å; P542-T561 HydrophobicContact CG-CG2 4.11Å; P542-A564 HydrophobicContact CB-CB 4.39Å; P542-A564 HydrophobicContact CG-CB 3.5Å; P542-A564 VanDerWaalsContact CG-CB 3.5Å; P542-F566 HydrophobicContact CB-CZ 4.27Å; P542-F566 HydrophobicContact CG-CZ 4.5Å; P542-V585 HydrophobicContact CB-CG1 4.31Å; P542-W586 CarbonylContact C-O 3.56Å; P542-W586 WeakPolarHBondContact CA-O 3.44Å; P542-L596 HydrophobicContact CB-CD1 4.49Å
543Y96.2Very high87.8Confident11 Ų1162.5 Ų62.54%0.04330%0.303CS..EExtended strand (participates in β ladder)trans-136.4159.4164.572.5-91.8000111L545 R554 V557 W586 D593Y543-L545 HydrophobicContact CE2-CB 4.46Å; Y543-R554 HydrophobicContact CD2-CG 3.76Å; Y543-R554 HydrophobicContact CE2-CG 4.04Å; Y543-V557 HydrophobicContact CD1-CG2 4.21Å; Y543-V557 HydrophobicContact CG-CG2 4.46Å; Y543-W586 HydrophobicContact CD1-CB 3.94Å; Y543-W586 HydrophobicContact CD2-CB 4.2Å; Y543-W586 HydrophobicContact CE1-CB 3.42Å; Y543-W586 VanDerWaalsContact CE1-CB 3.42Å; Y543-W586 HydrophobicContact CE1-CG 4.37Å; Y543-W586 HydrophobicContact CE2-CB 3.69Å; Y543-W586 AromaticContact CE2-CG 3.98Å; Y543-W586 HydrophobicContact CE2-CG 3.98Å; Y543-W586 HydrophobicContact CG-CB 4.32Å; Y543-W586 AromaticContact CZ-CG 3.77Å; Y543-W586 PolarHBondContact N-O 3.25Å; Y543-W586 PolarHBondContact O-N 3.1Å; Y543-D593 HydrophobicContact CE1-CB 4.23Å; Y543-D593 WeakPolarHBondContact CE1-OD2 3.48Å; Y543-D593 VanDerWaalsContact CZ-OD2 3.26Å; Y543-D593 PolarHBondContact OH-OD2 3.48Å
544V97.2Very high88.3Confident0 Ų061.9 Ų61.90%030%0.297CS..EExtended strand (participates in β ladder)trans-109.6138.9-179.5177.80000110.7I525 I546 R554 S555 F566 V583 Q584 V585 I631I525-V544 HydrophobicContact CG1-CG1 4.17Å; I525-V544 HydrophobicContact CG2-CG1 4.46Å; I525-V544 HydrophobicContact CG2-CG2 4.26Å; V544-I546 HydrophobicContact CG1-CG1 3.99Å; V544-R554 CarbonylContact O-C 3.38Å; V544-R554 WeakPolarHBondContact O-CA 3.2Å; V544-S555 PolarHBondContact N-OG 2.91Å; V544-S555 PolarHBondContact O-N 3.03Å; V544-F566 HydrophobicContact CG2-CD1 4.05Å; V544-F566 HydrophobicContact CG2-CD2 3.67Å; V544-F566 HydrophobicContact CG2-CE1 3.89Å; V544-F566 HydrophobicContact CG2-CE2 3.48Å; V544-F566 VanDerWaalsContact CG2-CE2 3.48Å; V544-F566 HydrophobicContact CG2-CG 3.95Å; V544-F566 HydrophobicContact CG2-CZ 3.6Å; V544-V583 HydrophobicContact CG1-CG1 3.5Å; V544-V583 VanDerWaalsContact CG1-CG1 3.5Å; V544-Q584 CarbonylContact C-O 3.58Å; V544-Q584 VanDerWaalsContact CA-O 3.32Å; V544-Q584 WeakPolarHBondContact CA-O 3.37Å; V544-V585 HydrophobicContact CG2-CG2 4.42Å; V544-I631 HydrophobicContact CG2-CD1 4.38Å
545L97Very high88.9Confident21 Ų2159.8 Ų59.811%0.1129%0.289CS..EExtended strand (participates in β ladder)trans-123107.6174.1-175.763.2000109.2Y543 K547 K552 V553 R554 Q584Y543-L545 HydrophobicContact CE2-CB 4.46Å; L545-K547 HydrophobicContact CD2-CD 4.49Å; L545-K547 HydrophobicContact CG-CG 4.2Å; L545-K552 HydrophobicContact CD1-CB 4.12Å; L545-V553 CarbonylContact C-O 3.59Å; L545-V553 WeakPolarHBondContact CA-O 3.19Å; L545-R554 HydrophobicContact CD1-CB 4Å; L545-R554 HydrophobicContact CD1-CG 4.48Å; L545-Q584 HydrophobicContact CB-CB 4.4Å; L545-Q584 PolarHBondContact N-O 2.81Å; L545-Q584 PolarHBondContact O-N 2.82Å
546I97.4Very high89.8Confident0 Ų059.6 Ų59.60%029%0.29CS..EExtended strand (participates in β ladder)trans-92.7119.8178.4-46.9173.4000107.8I523 I525 V544 K552 V553 T568 A570 F572 I581 I582 V583I523-I546 HydrophobicContact CD1-CG2 4.42Å; I523-I546 HydrophobicContact CG2-CD1 4.14Å; I523-I546 HydrophobicContact CG2-CG2 3.96Å; I525-I546 HydrophobicContact CD1-CD1 4.04Å; I525-I546 HydrophobicContact CD1-CG1 4.36Å; I525-I546 HydrophobicContact CG1-CD1 3.59Å; I525-I546 HydrophobicContact CG1-CG1 4.14Å; V544-I546 HydrophobicContact CG1-CG1 3.99Å; I546-K552 CarbonylContact O-C 3.55Å; I546-K552 VanDerWaalsContact O-CA 3.25Å; I546-K552 WeakPolarHBondContact O-CA 3.48Å; I546-V553 HydrophobicContact CB-CB 4.48Å; I546-V553 PolarHBondContact N-O 2.98Å; I546-V553 PolarHBondContact O-N 2.87Å; I546-T568 HydrophobicContact CD1-CG2 4.13Å; I546-A570 HydrophobicContact CD1-CB 3.94Å; I546-F572 HydrophobicContact CB-CZ 4.33Å; I546-F572 HydrophobicContact CG2-CE2 3.6Å; I546-F572 HydrophobicContact CG2-CZ 3.76Å; I546-I581 HydrophobicContact CG2-CG2 3.78Å; I546-I582 CarbonylContact C-O 3.53Å; I546-V583 HydrophobicContact CG2-CG2 4.43Å
547K96.1Very high91Very high64 Ų6449.4 Ų49.428%0.27826%0.257SS..EExtended strand (participates in β ladder)trans-117.7136.4179.7-62.3175.3175.6166.80110.3L545 Q551 K552 I581 I582L545-K547 HydrophobicContact CD2-CD 4.49Å; L545-K547 HydrophobicContact CG-CG 4.2Å; K547-Q551 WeakPolarHBondContact CA-O 3.37Å; K547-K552 HydrophobicContact CG-CB 4.28Å; K547-I581 WeakPolarHBondContact O-CA 3.26Å; K547-I582 HydrophobicContact CB-CB 4.28Å; K547-I582 PolarHBondContact N-O 3Å; K547-I582 PolarHBondContact O-N 3.04Å
548C95.2Very high92.3Very high3 Ų347.6 Ų47.62%0.0224%0.238CC..EExtended strand (participates in β ladder)trans-145.5119.6169.1-173.20000107.9N550 Q551 F572 I581C548-N550 PolarHBondContact O-N 2.6Å; C548-Q551 PolarHBondContact N-O 2.88Å; C548-Q551 PolarHBondContact O-N 3.43Å; C548-F572 HydrophobicContact CB-CB 4.11Å; C548-F572 HydrophobicContact CB-CD1 3.56Å; C548-F572 HydrophobicContact CB-CD2 3.89Å; C548-F572 HydrophobicContact CB-CE1 3.86Å; C548-F572 HydrophobicContact CB-CE2 4.17Å; C548-F572 HydrophobicContact CB-CG 3.57Å; C548-F572 HydrophobicContact CB-CZ 4.15Å; C548-I581 HydrophobicContact CB-CG1 4.11Å
549E91.9Very high93.4Very high70 Ų7054.6 Ų54.633%0.32727%0.266SS..THydrogen-bonded Turntrans50.7-125.2-172.7-55.2176.1177.800110.8Q551 K575 N576E549-Q551 VanDerWaalsContact C-N 3.33Å; E549-K575 PolarHBondContact OE1-N 2.68Å; E549-N576 PolarHBondContact OE1-N 3.06Å
550N89.7Confident93.8Very high172 Ų17259.3 Ų59.392%0.9229%0.29SS*.THydrogen-bonded Turntrans-88.11.7179.2-64.2-18.8000113.6C548C548-N550 PolarHBondContact O-N 2.6Å
551Q93.3Very high94Very high94 Ų9460.8 Ų60.844%0.43930%0.299SS..EExtended strand (participates in β ladder)trans-99.3144.7-178.2-60.3-170.40.900111.2K547 C548 E549 F572K547-Q551 WeakPolarHBondContact CA-O 3.37Å; C548-Q551 PolarHBondContact N-O 2.88Å; C548-Q551 PolarHBondContact O-N 3.43Å; E549-Q551 VanDerWaalsContact C-N 3.33Å; Q551-F572 HydrophobicContact CB-CD1 3.94Å; Q551-F572 HydrophobicContact CB-CE1 3.85Å
552K95.9Very high93.8Very high161 Ų16159.8 Ų59.870%0.730%0.295SS*.EExtended strand (participates in β ladder)trans-140.7141.5177.163.9-174.9178.6-177.60111.4L545 I546 K547L545-K552 HydrophobicContact CD1-CB 4.12Å; I546-K552 CarbonylContact O-C 3.55Å; I546-K552 VanDerWaalsContact O-CA 3.25Å; I546-K552 WeakPolarHBondContact O-CA 3.48Å; K547-K552 HydrophobicContact CG-CB 4.28Å
553V96.6Very high93.7Very high10 Ų1063 Ų636%0.06132%0.317CS..EExtended strand (participates in β ladder)trans-126.6129.5173179.20000108.2D433 N434 L545 I546 T568 A570 F572D433-V553 HydrophobicContact CB-CG1 3.88Å; N434-V553 HydrophobicContact CB-CG2 3.77Å; L545-V553 CarbonylContact C-O 3.59Å; L545-V553 WeakPolarHBondContact CA-O 3.19Å; I546-V553 HydrophobicContact CB-CB 4.48Å; I546-V553 PolarHBondContact N-O 2.98Å; I546-V553 PolarHBondContact O-N 2.87Å; V553-T568 HydrophobicContact CG1-CG2 4.1Å; V553-A570 HydrophobicContact CB-CB 4Å; V553-A570 HydrophobicContact CG1-CB 4.24Å; V553-A570 HydrophobicContact CG2-CB 3.74Å; V553-F572 HydrophobicContact CG2-CE1 4.4Å; V553-F572 HydrophobicContact CG2-CZ 4.19Å
554R95.3Very high93.5Very high122 Ų12262.5 Ų62.546%0.4632%0.316SS..EExtended strand (participates in β ladder)trans-114.5131.4-178.3-173.9-175.3175.4157.14.5109.2Y543 V544 L545 D593Y543-R554 HydrophobicContact CD2-CG 3.76Å; Y543-R554 HydrophobicContact CE2-CG 4.04Å; V544-R554 CarbonylContact O-C 3.38Å; V544-R554 WeakPolarHBondContact O-CA 3.2Å; L545-R554 HydrophobicContact CD1-CB 4Å; L545-R554 HydrophobicContact CD1-CG 4.48Å; R554-D593 IonicContact NH2-OD2 3.33Å; R554-D593 PolarHBondContact NH2-OD2 2.82Å
555S94.8Very high93.3Very high8 Ų867.5 Ų67.56%0.05635%0.346CS..PPolyproline II helixtrans-73.5169.8172.875.80000112.1V544 T568V544-S555 PolarHBondContact N-OG 2.91Å; V544-S555 PolarHBondContact O-N 3.03Å; S555-T568 WeakPolarHBondContact CA-OG1 3.39Å; S555-T568 WeakPolarHBondContact CB-OG1 3.44Å
556T91.6Very high93Very high65 Ų6566.7 Ų66.740%0.39934%0.341SS..PPolyproline II helixtrans-65.6154.7160.6560000110.5Q558T556-Q558 PolarHBondContact OG1-NE2 3.44Å
557V93.2Very high92.3Very high54 Ų5469.3 Ų69.333%0.32736%0.355SS..PPolyproline II helixtrans-77.1132.1172.8-177.80000108.8D541 Y543D541-V557 HydrophobicContact CB-CG1 3.83Å; Y543-V557 HydrophobicContact CD1-CG2 4.21Å; Y543-V557 HydrophobicContact CG-CG2 4.46Å
558Q92.3Very high92.2Very high59 Ų5966.5 Ų66.528%0.27634%0.344SS..PPolyproline II helixtrans-93.5133.1167.8-58.3-56.8-42.100107.9D541 P542 T556 T561 A564 F566D541-Q558 CarbonylContact C-O 3.54Å; D541-Q558 VanDerWaalsContact C-O 3.26Å; D541-Q558 WeakPolarHBondContact CA-O 3.43Å; P542-Q558 VanDerWaalsContact CD-O 3.25Å; P542-Q558 WeakPolarHBondContact CD-O 3.22Å; P542-Q558 HydrophobicContact CG-CB 4.28Å; P542-Q558 PolarHBondContact O-N 2.91Å; T556-Q558 PolarHBondContact OG1-NE2 3.44Å; Q558-T561 HydrophobicContact CB-CG2 3.84Å; Q558-A564 HydrophobicContact CB-CB 3.94Å; Q558-A564 HydrophobicContact CG-CB 3.85Å; Q558-F566 HydrophobicContact CG-CD1 4.27Å; Q558-F566 HydrophobicContact CG-CE1 3.85Å; Q558-F566 HydrophobicContact CG-CZ 4.49Å
559Q90.9Very high92.2Very high166 Ų16666.5 Ų66.578%0.77634%0.343SS*.PPolyproline II helixtrans-92.3140.1-172.6-67.8-179.8-19.200111.6D541 T561D541-Q559 VanDerWaalsContact OD1-CA 3.31Å; D541-Q559 WeakPolarHBondContact OD1-CA 3.35Å; Q559-T561 PolarHBondContact O-N 3.29Å
560D89.6Confident92.4Very high103 Ų10363.1 Ų63.155%0.55133%0.328SS*.SBendtrans46.652.1168.6-166.323.9000114.3G539 A540 D541G539-D560 WeakPolarHBondContact CA-OD1 3.48Å; A540-D560 CarbonylContact O-C 3.16Å; A540-D560 WeakPolarHBondContact O-CA 3.3Å; A540-D560 PolarHBondContact O-N 2.9Å; D541-D560 PolarHBondContact OD1-N 2.64Å
561T90.8Very high92.7Very high36 Ų3655.2 Ų55.222%0.22129%0.285CS..  trans-146.3143.1-179.3-175.80000113.7A540 P542 Q558 Q559 S563 A564A540-T561 PolarHBondContact O-N 3.44Å; P542-T561 VanDerWaalsContact CD-O 3.27Å; P542-T561 WeakPolarHBondContact CD-O 3.36Å; P542-T561 HydrophobicContact CG-CG2 4.11Å; Q558-T561 HydrophobicContact CB-CG2 3.84Å; Q559-T561 PolarHBondContact O-N 3.29Å; T561-S563 VanDerWaalsContact OG1-C 3.24Å; T561-S563 PolarHBondContact OG1-N 2.84Å; T561-S563 PolarHBondContact OG1-O 2.95Å; T561-A564 HydrophobicContact CG2-CB 4.01Å
562T89.9Confident92.9Very high36 Ų3650.8 Ų50.822%0.22126%0.264CS..SBendtrans-99.4-3.3168.653.20000113.2G530 L531 K533G530-T562 PolarHBondContact N-O 2.84Å; L531-T562 WeakPolarHBondContact CB-O 3.3Å; L531-T562 WeakPolarHBondContact CG-O 3.41Å; L531-T562 PolarHBondContact N-O 3.31Å; L531-T562 WeakPolarHBondContact O-CG2 3.34Å; K533-T562 HydrophobicContact CG-CG2 3.95Å
563S92.1Very high92.9Very high67 Ų6744.1 Ų44.147%0.46924%0.235SC..SBendtrans-130.690.6176.3-68.60000108.9A528 T561A528-S563 CarbonylContact O-C 3.43Å; A528-S563 WeakPolarHBondContact O-CA 3.26Å; T561-S563 VanDerWaalsContact OG1-C 3.24Å; T561-S563 PolarHBondContact OG1-N 2.84Å; T561-S563 PolarHBondContact OG1-O 2.95Å
564A92.5Very high92.8Very high2 Ų243.7 Ų43.72%0.01723%0.232CC..EExtended strand (participates in β ladder)trans-100.2132.9-173.900000111.1S527 A528 P542 Q558 T561 F566S527-A564 CarbonylContact C-O 3.53Å; S527-A564 WeakPolarHBondContact CA-O 3.49Å; S527-A564 WeakPolarHBondContact CB-O 3.45Å; A528-A564 PolarHBondContact N-O 3.23Å; A528-A564 PolarHBondContact O-N 2.9Å; P542-A564 HydrophobicContact CB-CB 4.39Å; P542-A564 HydrophobicContact CG-CB 3.5Å; P542-A564 VanDerWaalsContact CG-CB 3.5Å; Q558-A564 HydrophobicContact CB-CB 3.94Å; Q558-A564 HydrophobicContact CG-CB 3.85Å; T561-A564 HydrophobicContact CG2-CB 4.01Å; A564-F566 HydrophobicContact CB-CE1 4.17Å; A564-F566 HydrophobicContact CB-CE2 3.7Å; A564-F566 HydrophobicContact CB-CZ 3.47Å; A564-F566 VanDerWaalsContact CB-CZ 3.47Å
565V92.9Very high92.7Very high105 Ų10541.9 Ų41.964%0.63623%0.228SC*.EExtended strand (participates in β ladder)trans-94.7127.4168.2178.70000108.1H526H526-V565 WeakPolarHBondContact O-CA 3.41Å; H526-V565 WeakPolarHBondContact O-CG1 3.47Å
566F90.8Very high92.5Very high4 Ų445.5 Ų45.52%0.01825%0.247CC..EExtended strand (participates in β ladder)trans-107.8142.5174.9-58-74.6000108.8I525 H526 A528 P542 V544 Q558 A564I525-F566 HydrophobicContact CB-CB 4.24Å; I525-F566 HydrophobicContact CG2-CB 4.02Å; I525-F566 HydrophobicContact CG2-CD2 3.95Å; I525-F566 HydrophobicContact CG2-CG 4.28Å; I525-F566 CarbonylContact O-C 3.59Å; H526-F566 PolarHBondContact O-N 3.01Å; H526-F566 VanDerWaalsContact O-O 3.08Å; A528-F566 HydrophobicContact CB-CE2 3.77Å; P542-F566 HydrophobicContact CB-CZ 4.27Å; P542-F566 HydrophobicContact CG-CZ 4.5Å; V544-F566 HydrophobicContact CG2-CD1 4.05Å; V544-F566 HydrophobicContact CG2-CD2 3.67Å; V544-F566 HydrophobicContact CG2-CE1 3.89Å; V544-F566 HydrophobicContact CG2-CE2 3.48Å; V544-F566 VanDerWaalsContact CG2-CE2 3.48Å; V544-F566 HydrophobicContact CG2-CG 3.95Å; V544-F566 HydrophobicContact CG2-CZ 3.6Å; Q558-F566 HydrophobicContact CG-CD1 4.27Å; Q558-F566 HydrophobicContact CG-CE1 3.85Å; Q558-F566 HydrophobicContact CG-CZ 4.49Å; A564-F566 HydrophobicContact CB-CE1 4.17Å; A564-F566 HydrophobicContact CB-CE2 3.7Å; A564-F566 HydrophobicContact CB-CZ 3.47Å; A564-F566 VanDerWaalsContact CB-CZ 3.47Å
567D83.2Confident92.5Very high55 Ų5544.4 Ų44.429%0.29424%0.238SC..EExtended strand (participates in β ladder)trans-120.749.2169.8-176.132.9000108.9K430 K524K430-D567 WeakPolarHBondContact CD-OD2 3.3Å; K430-D567 WeakPolarHBondContact CE-OD2 3.4Å; K430-D567 IonicContact NZ-OD2 3.55Å; K430-D567 PolarHBondContact NZ-OD2 3.47Å; K524-D567 IonicContact NZ-OD1 2.89Å
568T93.3Very high92.3Very high5 Ų548.6 Ų48.63%0.03126%0.258CS..EExtended strand (participates in β ladder)trans-105.8128.8-176.1-62.70000109.4I525 I546 V553 S555I525-T568 PolarHBondContact N-O 3.42Å; I546-T568 HydrophobicContact CD1-CG2 4.13Å; V553-T568 HydrophobicContact CG1-CG2 4.1Å; S555-T568 WeakPolarHBondContact CA-OG1 3.39Å; S555-T568 WeakPolarHBondContact CB-OG1 3.44Å
569Q95.4Very high92.2Very high2 Ų247.3 Ų47.31%0.00926%0.256CS..EExtended strand (participates in β ladder)trans-128.1138.7-178.3-56.1176.925.500108.9E432 D433 V444 I523 K524E432-Q569 CarbonylContact C-O 3.54Å; E432-Q569 VanDerWaalsContact CA-O 3.27Å; E432-Q569 WeakPolarHBondContact CA-O 3.24Å; E432-Q569 HydrophobicContact CB-CB 4.29Å; E432-Q569 HydrophobicContact CG-CB 3.94Å; D433-Q569 PolarHBondContact N-O 2.82Å; V444-Q569 PolarHBondContact O-NE2 2.72Å; I523-Q569 CarbonylContact O-C 3.39Å; I523-Q569 VanDerWaalsContact O-CA 3.3Å; I523-Q569 WeakPolarHBondContact O-CA 3.33Å; K524-Q569 HydrophobicContact CB-CG 4.18Å; K524-Q569 HydrophobicContact CD-CG 4.15Å; K524-Q569 HydrophobicContact CG-CG 3.94Å
570A96.6Very high92.3Very high0 Ų041.4 Ų41.40%023%0.232CC..EExtended strand (participates in β ladder)trans-135.7146.5178.500000111Q522 I523 I546 V553 F572Q522-A570 CarbonylContact C-O 3.5Å; Q522-A570 WeakPolarHBondContact CA-O 3.29Å; I523-A570 HydrophobicContact CG2-CB 3.81Å; I523-A570 PolarHBondContact N-O 3.29Å; I523-A570 PolarHBondContact O-N 3.13Å; I546-A570 HydrophobicContact CD1-CB 3.94Å; V553-A570 HydrophobicContact CB-CB 4Å; V553-A570 HydrophobicContact CG1-CB 4.24Å; V553-A570 HydrophobicContact CG2-CB 3.74Å; A570-F572 HydrophobicContact CB-CD2 4.44Å; A570-F572 HydrophobicContact CB-CE2 3.56Å; A570-F572 HydrophobicContact CB-CZ 3.71Å
571I96.9Very high92.6Very high5 Ų536.5 Ų36.53%0.02621%0.206CC..EExtended strand (participates in β ladder)trans-124.2130.6173.7-174.2167.4000109.9E432 N434 R435 V520 T521 Q522 Y573E432-I571 HydrophobicContact CB-CB 4.15Å; E432-I571 HydrophobicContact CB-CG2 3.84Å; E432-I571 HydrophobicContact CG-CB 3.9Å; E432-I571 HydrophobicContact CG-CG2 4.12Å; N434-I571 PolarHBondContact ND2-O 3Å; N434-I571 PolarHBondContact OD1-N 2.93Å; N434-I571 PolarHBondContact OD1-O 3.23Å; R435-I571 HydrophobicContact CB-CG2 4.12Å; V520-I571 HydrophobicContact CG2-CD1 3.72Å; V520-I571 HydrophobicContact CG2-CG1 3.75Å; T521-I571 CarbonylContact O-C 3.47Å; T521-I571 WeakPolarHBondContact O-CA 3.23Å; Q522-I571 HydrophobicContact CG-CB 4.24Å; Q522-I571 HydrophobicContact CG-CD1 3.94Å; Q522-I571 HydrophobicContact CG-CG1 3.98Å; I571-Y573 HydrophobicContact CD1-CE2 4.09Å; I571-Y573 HydrophobicContact CG1-CE2 4.13Å
572F96.4Very high92.8Very high2 Ų237 Ų371%0.00921%0.207CC..EExtended strand (participates in β ladder)trans-125130.5-178.3-59.4-75.5000110.9V520 T521 I523 I546 C548 Q551 V553 A570 R574 I581V520-F572 CarbonylContact C-O 3.55Å; V520-F572 WeakPolarHBondContact CA-O 3.41Å; T521-F572 PolarHBondContact N-O 3.19Å; T521-F572 PolarHBondContact O-N 2.78Å; I523-F572 HydrophobicContact CG2-CD2 4.48Å; I523-F572 HydrophobicContact CG2-CE2 3.99Å; I546-F572 HydrophobicContact CB-CZ 4.33Å; I546-F572 HydrophobicContact CG2-CE2 3.6Å; I546-F572 HydrophobicContact CG2-CZ 3.76Å; C548-F572 HydrophobicContact CB-CB 4.11Å; C548-F572 HydrophobicContact CB-CD1 3.56Å; C548-F572 HydrophobicContact CB-CD2 3.89Å; C548-F572 HydrophobicContact CB-CE1 3.86Å; C548-F572 HydrophobicContact CB-CE2 4.17Å; C548-F572 HydrophobicContact CB-CG 3.57Å; C548-F572 HydrophobicContact CB-CZ 4.15Å; Q551-F572 HydrophobicContact CB-CD1 3.94Å; Q551-F572 HydrophobicContact CB-CE1 3.85Å; V553-F572 HydrophobicContact CG2-CE1 4.4Å; V553-F572 HydrophobicContact CG2-CZ 4.19Å; A570-F572 HydrophobicContact CB-CD2 4.44Å; A570-F572 HydrophobicContact CB-CE2 3.56Å; A570-F572 HydrophobicContact CB-CZ 3.71Å; F572-R574 HydrophobicContact CB-CG 4.12Å; F572-I581 HydrophobicContact CD2-CD1 4.16Å
573Y95.3Very high93.1Very high20 Ų2035.3 Ų35.38%0.07820%0.196CC..EExtended strand (participates in β ladder)trans-98.197.9170.8-72.5-100000107.9Y437 K504 P505 R519 V520 I571 L641Y437-Y573 HydrophobicContact CD2-CD2 4.03Å; Y437-Y573 HydrophobicContact CD2-CE1 4.43Å; Y437-Y573 AromaticContact CD2-CE2 3.37Å; Y437-Y573 HydrophobicContact CD2-CE2 3.37Å; Y437-Y573 AromaticContact CD2-CZ 3.59Å; Y437-Y573 AromaticContact CE2-CD2 3.98Å; Y437-Y573 HydrophobicContact CE2-CD2 3.98Å; Y437-Y573 AromaticContact CE2-CE2 3.82Å; Y437-Y573 HydrophobicContact CE2-CE2 3.82Å; Y437-Y573 HydrophobicContact CG-CE2 4.4Å; K504-Y573 HydrophobicContact CB-CE1 4.25Å; P505-Y573 HydrophobicContact CG-CD1 3.55Å; P505-Y573 HydrophobicContact CG-CD2 4.31Å; P505-Y573 HydrophobicContact CG-CE1 4.1Å; P505-Y573 HydrophobicContact CG-CG 3.64Å; R519-Y573 CarbonylContact O-C 3.58Å; V520-Y573 HydrophobicContact CB-CD1 4.34Å; V520-Y573 HydrophobicContact CB-CE1 4.29Å; V520-Y573 HydrophobicContact CG2-CD1 4.37Å; V520-Y573 HydrophobicContact CG2-CD2 4.5Å; V520-Y573 HydrophobicContact CG2-CE1 4.1Å; V520-Y573 HydrophobicContact CG2-CE2 4.19Å; I571-Y573 HydrophobicContact CD1-CE2 4.09Å; I571-Y573 HydrophobicContact CG1-CE2 4.13Å; Y573-L641 HydrophobicContact CD1-CB 4.49Å; Y573-L641 HydrophobicContact CD1-CD2 4.18Å; Y573-L641 HydrophobicContact CE1-CB 4.26Å
574R94.3Very high93.3Very high1 Ų132.7 Ų32.70%0.00418%0.177CC..EExtended strand (participates in β ladder)trans-89.7130.6-166-60.8170.565.6-166.42.6111.2P517 R518 R519 T521 F572 I577 S579 A602 A603P517-R574 CarbonylContact C-O 3.55Å; P517-R574 VanDerWaalsContact CA-O 3.3Å; P517-R574 WeakPolarHBondContact CA-O 3.5Å; R518-R574 PolarHBondContact N-O 3.02Å; R519-R574 HydrophobicContact CB-CB 4.39Å; R519-R574 PolarHBondContact N-O 2.74Å; R519-R574 PolarHBondContact O-N 3.17Å; T521-R574 WeakPolarHBondContact OG1-CD 3.5Å; T521-R574 PolarHBondContact OG1-NH1 3.15Å; F572-R574 HydrophobicContact CB-CG 4.12Å; R574-I577 PolarHBondContact NH2-O 3.13Å; R574-S579 PolarHBondContact NH2-O 3Å; R574-A602 PolarHBondContact NH1-O 3.08Å; R574-A602 VanDerWaalsContact NH1-O 3.15Å; R574-A602 PolarHBondContact NH2-O 3.33Å; R574-A603 PolarHBondContact NH1-O 2.81Å
575K93.3Very high93.5Very high84 Ų8432.6 Ų32.637%0.36518%0.176SC..SBendtrans-92.2-43.9173.6-61-179.3176-167.20110.7C514 G515 P517 E549C514-K575 WeakPolarHBondContact O-CD 3.33Å; C514-K575 PolarHBondContact O-NZ 3.43Å; G515-K575 WeakPolarHBondContact O-CE 3.23Å; G515-K575 PolarHBondContact O-NZ 3.38Å; P517-K575 HydrophobicContact CG-CG 4.25Å; E549-K575 PolarHBondContact OE1-N 2.68Å
576N90.9Very high93.7Very high85 Ų8529.2 Ų29.246%0.45515%0.152SC..  trans-97.1100176.2-174.1-12.1000109.3E549 D578 S579E549-N576 PolarHBondContact OE1-N 3.06Å; N576-D578 PolarHBondContact O-N 3.1Å; N576-D578 PolarHBondContact OD1-N 2.78Å; N576-D578 VanDerWaalsContact OD1-N 3.12Å; N576-S579 WeakPolarHBondContact O-CB 3.3Å; N576-S579 PolarHBondContact O-N 2.77Å; N576-S579 PolarHBondContact OD1-N 3.44Å
577I91Very high93.8Very high42 Ų4229.2 Ų29.222%0.21515%0.152CC..THydrogen-bonded Turntrans-70.2-20.3-177.262.3175.1000113.2R518 R519 R574R518-I577 HydrophobicContact CB-CG2 4.23Å; R519-I577 HydrophobicContact CB-CG2 4.05Å; R574-I577 PolarHBondContact NH2-O 3.13Å
578D89.1Confident94.2Very high141 Ų14128 Ų2875%0.75415%0.148SC*.THydrogen-bonded Turntrans-85.4-17.7178.8-55.6-45.8000111.9N576 P580N576-D578 PolarHBondContact O-N 3.1Å; N576-D578 PolarHBondContact OD1-N 2.78Å; N576-D578 VanDerWaalsContact OD1-N 3.12Å; D578-P580 WeakPolarHBondContact O-CD 3.35Å
579S90.6Very high94Very high32 Ų3231 Ų3122%0.22416%0.164CC..SBendtrans-70.8121.7175.5-170.30000110.1R574 N576R574-S579 PolarHBondContact NH2-O 3Å; N576-S579 WeakPolarHBondContact O-CB 3.3Å; N576-S579 PolarHBondContact O-N 2.77Å; N576-S579 PolarHBondContact OD1-N 3.44Å
580P93.4Very high93.3Very high42 Ų4238.1 Ų38.127%0.27321%0.207SC..PPolyproline II helixtrans-72.3155.2-178.230.3-35.3000111.6D578 L600 L601D578-P580 WeakPolarHBondContact O-CD 3.35Å; P580-L600 HydrophobicContact CB-CB 4.48Å; P580-L600 HydrophobicContact CG-CD2 4.28Å; P580-L601 CarbonylContact C-O 3.48Å; P580-L601 VanDerWaalsContact CA-O 3.27Å; P580-L601 WeakPolarHBondContact CA-O 3.39Å; P580-L601 WeakPolarHBondContact CB-O 3.4Å
581I95.1Very high92.6Very high0 Ų046.5 Ų46.50%025%0.251CS..EExtended strand (participates in β ladder)trans-80.3124.1162.7-60.7178.8000107.7T521 I523 I546 K547 C548 F572 V583 L601 A603T521-I581 HydrophobicContact CG2-CD1 3.3Å; I523-I581 HydrophobicContact CD1-CG2 4.28Å; I546-I581 HydrophobicContact CG2-CG2 3.78Å; K547-I581 WeakPolarHBondContact O-CA 3.26Å; C548-I581 HydrophobicContact CB-CG1 4.11Å; F572-I581 HydrophobicContact CD2-CD1 4.16Å; I581-V583 HydrophobicContact CG2-CG2 4.43Å; I581-L601 HydrophobicContact CB-CB 4.22Å; I581-L601 PolarHBondContact N-O 3.42Å; I581-L601 PolarHBondContact O-N 3.15Å; I581-A603 HydrophobicContact CD1-CB 4.01Å
582I95.8Very high92.1Very high47 Ų4750.9 Ų50.924%0.24128%0.281CS..EExtended strand (participates in β ladder)trans-102.6115.3-178.1-45.4-178.2000107.9I546 K547 Q584 Q598 L600I546-I582 CarbonylContact C-O 3.53Å; K547-I582 HydrophobicContact CB-CB 4.28Å; K547-I582 PolarHBondContact N-O 3Å; K547-I582 PolarHBondContact O-N 3.04Å; I582-Q584 HydrophobicContact CG2-CG 3.71Å; I582-Q598 HydrophobicContact CG2-CB 4.37Å; I582-L600 HydrophobicContact CB-CD2 4.08Å; I582-L600 HydrophobicContact CD1-CD2 4.23Å; I582-L600 HydrophobicContact CG1-CD2 3.65Å; I582-L600 HydrophobicContact CG2-CD2 3.83Å
583V96.8Very high91.9Very high0 Ų052.7 Ų52.70%029%0.29CS..EExtended strand (participates in β ladder)trans-102.7111.6173.5-172.10000107.9I523 I525 V544 I546 I581 Q598 A599 L601 I631I523-V583 HydrophobicContact CD1-CG2 3.6Å; I525-V583 HydrophobicContact CD1-CG1 3.73Å; I525-V583 HydrophobicContact CD1-CG2 4.11Å; V544-V583 HydrophobicContact CG1-CG1 3.5Å; V544-V583 VanDerWaalsContact CG1-CG1 3.5Å; I546-V583 HydrophobicContact CG2-CG2 4.43Å; I581-V583 HydrophobicContact CG2-CG2 4.43Å; V583-Q598 CarbonylContact O-C 3.58Å; V583-Q598 WeakPolarHBondContact O-CA 3.44Å; V583-Q598 WeakPolarHBondContact O-CB 3.23Å; V583-A599 PolarHBondContact N-O 2.97Å; V583-A599 PolarHBondContact O-N 2.9Å; V583-L601 HydrophobicContact CG2-CD1 3.71Å; V583-I631 HydrophobicContact CB-CD1 4.4Å; V583-I631 HydrophobicContact CG1-CD1 3.37Å
584Q96.4Very high91.7Very high13 Ų1355.5 Ų55.56%0.06130%0.304CS..EExtended strand (participates in β ladder)trans-106.7137.1-179-54.8-170.8-41.800110.4V544 L545 I582 W586 F595 G597 Q598V544-Q584 CarbonylContact C-O 3.58Å; V544-Q584 VanDerWaalsContact CA-O 3.32Å; V544-Q584 WeakPolarHBondContact CA-O 3.37Å; L545-Q584 HydrophobicContact CB-CB 4.4Å; L545-Q584 PolarHBondContact N-O 2.81Å; L545-Q584 PolarHBondContact O-N 2.82Å; I582-Q584 HydrophobicContact CG2-CG 3.71Å; Q584-W586 VanDerWaalsContact CB-NE1 3.33Å; Q584-F595 HydrophobicContact CB-CE2 4.11Å; Q584-F595 HydrophobicContact CG-CE2 4.22Å; Q584-G597 WeakPolarHBondContact CA-O 3.26Å; Q584-Q598 HydrophobicContact CB-CB 4.47Å; Q584-Q598 HydrophobicContact CG-CB 3.99Å; Q584-Q598 VanDerWaalsContact NE2-OE1 3.11Å
585V96.4Very high91.7Very high0 Ų057.4 Ų57.40%031%0.313CS..EExtended strand (participates in β ladder)trans-104.4132.1171.3-168.50000108.3A528 L531 P542 V544 L596 G597 L616 I631A528-V585 HydrophobicContact CB-CG2 4.41Å; L531-V585 HydrophobicContact CD1-CG1 4.12Å; L531-V585 HydrophobicContact CD2-CG1 3.98Å; P542-V585 HydrophobicContact CB-CG1 4.31Å; V544-V585 HydrophobicContact CG2-CG2 4.42Å; V585-L596 HydrophobicContact CB-CB 4.31Å; V585-L596 HydrophobicContact CG1-CB 4.31Å; V585-L596 HydrophobicContact CG1-CD1 4.13Å; V585-L596 WeakPolarHBondContact O-CB 3.42Å; V585-L596 PolarHBondContact O-N 3.11Å; V585-G597 PolarHBondContact N-O 3.38Å; V585-G597 PolarHBondContact O-N 2.84Å; V585-L616 HydrophobicContact CB-CD1 4.3Å; V585-L616 HydrophobicContact CG2-CD1 3.96Å; V585-L616 HydrophobicContact CG2-CD2 3.87Å; V585-I631 HydrophobicContact CG2-CD1 3.88Å
586W95.8Very high91.7Very high34 Ų3453.7 Ų53.713%0.12930%0.297CS..EExtended strand (participates in β ladder)trans-132149.9-176.9-70.181.5000109.9P542 Y543 Q584 D593 Q594 F595P542-W586 CarbonylContact C-O 3.56Å; P542-W586 WeakPolarHBondContact CA-O 3.44Å; Y543-W586 HydrophobicContact CD1-CB 3.94Å; Y543-W586 HydrophobicContact CD2-CB 4.2Å; Y543-W586 HydrophobicContact CE1-CB 3.42Å; Y543-W586 VanDerWaalsContact CE1-CB 3.42Å; Y543-W586 HydrophobicContact CE1-CG 4.37Å; Y543-W586 HydrophobicContact CE2-CB 3.69Å; Y543-W586 AromaticContact CE2-CG 3.98Å; Y543-W586 HydrophobicContact CE2-CG 3.98Å; Y543-W586 HydrophobicContact CG-CB 4.32Å; Y543-W586 AromaticContact CZ-CG 3.77Å; Y543-W586 PolarHBondContact N-O 3.25Å; Y543-W586 PolarHBondContact O-N 3.1Å; Q584-W586 VanDerWaalsContact CB-NE1 3.33Å; W586-D593 HydrophobicContact CE3-CB 4Å; W586-D593 HydrophobicContact CZ3-CB 4.49Å; W586-D593 WeakPolarHBondContact CZ3-O 3.38Å; W586-Q594 CarbonylContact C-O 3.59Å; W586-Q594 VanDerWaalsContact CA-O 3.27Å; W586-Q594 WeakPolarHBondContact CA-O 3.27Å; W586-Q594 VanDerWaalsContact CE3-C 3.49Å; W586-F595 HydrophobicContact CD2-CB 4.35Å; W586-F595 HydrophobicContact CD2-CD2 4.31Å; W586-F595 AromaticContact CE2-CD2 3.84Å; W586-F595 HydrophobicContact CE3-CB 4.05Å; W586-F595 HydrophobicContact CH2-CB 4.2Å; W586-F595 HydrophobicContact CZ2-CB 4.42Å; W586-F595 AromaticContact CZ2-CD2 3.96Å; W586-F595 HydrophobicContact CZ2-CD2 3.96Å; W586-F595 HydrophobicContact CZ3-CB 3.98Å
587N93.6Very high91.9Very high3 Ų349.6 Ų49.62%0.01628%0.275CS..EExtended strand (participates in β ladder)trans-96.4125.1168.5-173.673.7000109.3Q534 A540 D541 N589 D593 Q594 L596Q534-N587 HydrophobicContact CG-CB 4.07Å; A540-N587 WeakPolarHBondContact CA-OD1 3.39Å; A540-N587 WeakPolarHBondContact CB-OD1 3.29Å; D541-N587 PolarHBondContact N-OD1 3.34Å; N587-N589 PolarHBondContact ND2-ND2 3.43Å; N587-N589 PolarHBondContact ND2-OD1 2.94Å; N587-D593 CarbonylContact O-C 3.49Å; N587-D593 VanDerWaalsContact O-CA 3.25Å; N587-D593 WeakPolarHBondContact O-CA 3.44Å; N587-D593 WeakPolarHBondContact O-CB 3.26Å; N587-Q594 HydrophobicContact CB-CB 4.25Å; N587-Q594 PolarHBondContact N-O 3.36Å; N587-Q594 PolarHBondContact O-N 3.17Å; N587-L596 HydrophobicContact CB-CD1 4.03Å; N587-L596 HydrophobicContact CB-CD2 4.12Å; N587-L596 HydrophobicContact CB-CG 4.09Å
588S92.5Very high92.2Very high31 Ų3148.2 Ų48.222%0.21727%0.267CS..  trans-72.5130.1174.3-162.30000109.8D541 D593D541-S588 PolarHBondContact O-N 3.31Å; S588-D593 WeakPolarHBondContact CA-OD1 3.37Å
589N87.9Confident92.5Very high68 Ų6841.8 Ų41.836%0.36423%0.234SC..  trans-133.8160.1177.3-76.1-42.4000110.6N587 L591 C592 D593N587-N589 PolarHBondContact ND2-ND2 3.43Å; N587-N589 PolarHBondContact ND2-OD1 2.94Å; N589-L591 VanDerWaalsContact C-N 3.33Å; N589-L591 PolarHBondContact O-N 2.79Å; N589-C592 VanDerWaalsContact CB-O 3.28Å; N589-C592 WeakPolarHBondContact CB-O 3.46Å; N589-C592 PolarHBondContact ND2-O 2.95Å; N589-D593 PolarHBondContact N-OD1 2.91Å; N589-D593 VanDerWaalsContact N-OD1 3.08Å
590V81.1Confident92.6Very high151 Ų15141.8 Ų41.892%0.91523%0.232SC*.SBendtrans-62.8-37.4-179.3-179.50000112.6
591L82.1Confident92.6Very high175 Ų17540.3 Ų40.392%0.91622%0.221SC*.SBendtrans-99.9-55.2-176.6-67.3174000113N589N589-L591 VanDerWaalsContact C-N 3.33Å; N589-L591 PolarHBondContact O-N 2.79Å
592C85.4Confident92.5Very high98 Ų9841.9 Ų41.966%0.66223%0.234SC*.  trans-148.8123.3-176.9-170.90000110.6N589N589-C592 VanDerWaalsContact CB-O 3.28Å; N589-C592 WeakPolarHBondContact CB-O 3.46Å; N589-C592 PolarHBondContact ND2-O 2.95Å
593D92.2Very high92.2Very high39 Ų3939.7 Ų39.721%0.20922%0.223CC..PPolyproline II helixtrans-60.6138.4177.5-68.1-7.5000110.7Y543 R554 W586 N587 S588 N589Y543-D593 HydrophobicContact CE1-CB 4.23Å; Y543-D593 WeakPolarHBondContact CE1-OD2 3.48Å; Y543-D593 VanDerWaalsContact CZ-OD2 3.26Å; Y543-D593 PolarHBondContact OH-OD2 3.48Å; R554-D593 IonicContact NH2-OD2 3.33Å; R554-D593 PolarHBondContact NH2-OD2 2.82Å; W586-D593 HydrophobicContact CE3-CB 4Å; W586-D593 HydrophobicContact CZ3-CB 4.49Å; W586-D593 WeakPolarHBondContact CZ3-O 3.38Å; N587-D593 CarbonylContact O-C 3.49Å; N587-D593 VanDerWaalsContact O-CA 3.25Å; N587-D593 WeakPolarHBondContact O-CA 3.44Å; N587-D593 WeakPolarHBondContact O-CB 3.26Å; S588-D593 WeakPolarHBondContact CA-OD1 3.37Å; N589-D593 PolarHBondContact N-OD1 2.91Å; N589-D593 VanDerWaalsContact N-OD1 3.08Å
594Q92.3Very high91.9Very high79 Ų7942 Ų4237%0.36924%0.239SC..EExtended strand (participates in β ladder)trans-103.6133.8-176.4-177.6175.3-11.600110.9W586 N587W586-Q594 CarbonylContact C-O 3.59Å; W586-Q594 VanDerWaalsContact CA-O 3.27Å; W586-Q594 WeakPolarHBondContact CA-O 3.27Å; W586-Q594 VanDerWaalsContact CE3-C 3.49Å; N587-Q594 HydrophobicContact CB-CB 4.25Å; N587-Q594 PolarHBondContact N-O 3.36Å; N587-Q594 PolarHBondContact O-N 3.17Å
595F94Very high91.5Very high42 Ų4243.3 Ų43.318%0.18425%0.249CC..EExtended strand (participates in β ladder)trans-76.5125.5177.7176.9-99.3000110.3Q584 W586 G597 Q598 R619Q584-F595 HydrophobicContact CB-CE2 4.11Å; Q584-F595 HydrophobicContact CG-CE2 4.22Å; W586-F595 HydrophobicContact CD2-CB 4.35Å; W586-F595 HydrophobicContact CD2-CD2 4.31Å; W586-F595 AromaticContact CE2-CD2 3.84Å; W586-F595 HydrophobicContact CE3-CB 4.05Å; W586-F595 HydrophobicContact CH2-CB 4.2Å; W586-F595 HydrophobicContact CZ2-CB 4.42Å; W586-F595 AromaticContact CZ2-CD2 3.96Å; W586-F595 HydrophobicContact CZ2-CD2 3.96Å; W586-F595 HydrophobicContact CZ3-CB 3.98Å; F595-G597 VanDerWaalsContact CE2-O 3.29Å; F595-G597 WeakPolarHBondContact CE2-O 3.25Å; F595-G597 VanDerWaalsContact CZ-CA 3.46Å; F595-G597 WeakPolarHBondContact CZ-O 3.48Å; F595-Q598 HydrophobicContact CE2-CB 4.07Å; F595-Q598 HydrophobicContact CZ-CB 3.83Å; F595-Q598 HydrophobicContact CZ-CG 3.93Å; F595-R619 HydrophobicContact CD1-CG 4.06Å; F595-R619 HydrophobicContact CE1-CG 3.65Å; F595-R619 HydrophobicContact CE2-CG 4.21Å; F595-R619 HydrophobicContact CG-CG 4.49Å; F595-R619 HydrophobicContact CZ-CG 3.72Å
596L93.4Very high91Very high5 Ų546.9 Ų46.93%0.02629%0.286CS..EExtended strand (participates in β ladder)trans-99.4-28.9179.6-62.3-178.6000112.7L531 Q534 P542 V585 N587 V627L531-L596 HydrophobicContact CB-CD1 4.46Å; L531-L596 HydrophobicContact CD1-CD1 4.3Å; Q534-L596 HydrophobicContact CG-CD2 4.17Å; P542-L596 HydrophobicContact CB-CD1 4.49Å; V585-L596 HydrophobicContact CB-CB 4.31Å; V585-L596 HydrophobicContact CG1-CB 4.31Å; V585-L596 HydrophobicContact CG1-CD1 4.13Å; V585-L596 WeakPolarHBondContact O-CB 3.42Å; V585-L596 PolarHBondContact O-N 3.11Å; N587-L596 HydrophobicContact CB-CD1 4.03Å; N587-L596 HydrophobicContact CB-CD2 4.12Å; N587-L596 HydrophobicContact CB-CG 4.09Å; L596-V627 VanDerWaalsContact O-CG2 3.24Å; L596-V627 WeakPolarHBondContact O-CG2 3.29Å
597G95Very high90.6Very high0 Ų048 Ų480%029%0.294CS..EExtended strand (participates in β ladder)trans161.5174.117900000112.8Q584 V585 F595 R617Q584-G597 WeakPolarHBondContact CA-O 3.26Å; V585-G597 PolarHBondContact N-O 3.38Å; V585-G597 PolarHBondContact O-N 2.84Å; F595-G597 VanDerWaalsContact CE2-O 3.29Å; F595-G597 WeakPolarHBondContact CE2-O 3.25Å; F595-G597 VanDerWaalsContact CZ-CA 3.46Å; F595-G597 WeakPolarHBondContact CZ-O 3.48Å; G597-R617 CarbonylContact C-O 3.58Å; G597-R617 WeakPolarHBondContact CA-O 3.46Å
598Q96.4Very high90.3Very high12 Ų1251.7 Ų51.76%0.05632%0.319CS..EExtended strand (participates in β ladder)trans-143159.9174.767.8179.813.600113.2I582 V583 Q584 F595 R617 G618 G620I582-Q598 HydrophobicContact CG2-CB 4.37Å; V583-Q598 CarbonylContact O-C 3.58Å; V583-Q598 WeakPolarHBondContact O-CA 3.44Å; V583-Q598 WeakPolarHBondContact O-CB 3.23Å; Q584-Q598 HydrophobicContact CB-CB 4.47Å; Q584-Q598 HydrophobicContact CG-CB 3.99Å; Q584-Q598 VanDerWaalsContact NE2-OE1 3.11Å; F595-Q598 HydrophobicContact CE2-CB 4.07Å; F595-Q598 HydrophobicContact CZ-CB 3.83Å; F595-Q598 HydrophobicContact CZ-CG 3.93Å; Q598-R617 PolarHBondContact N-O 3.2Å; Q598-R617 PolarHBondContact O-N 2.79Å; Q598-G618 PolarHBondContact NE2-O 3.49Å; Q598-G620 PolarHBondContact NE2-O 3.18Å
599A95.3Very high90Very high7 Ų755.9 Ų55.96%0.05833%0.33CS..EExtended strand (participates in β ladder)trans-122.5140.6166.900000110.1V583 L614 I631V583-A599 PolarHBondContact N-O 2.97Å; V583-A599 PolarHBondContact O-N 2.9Å; A599-L614 HydrophobicContact CB-CB 4.33Å; A599-L614 HydrophobicContact CB-CD1 4.14Å; A599-I631 HydrophobicContact CB-CG2 3.78Å
600L94.4Very high90Very high32 Ų3260 Ų6017%0.16835%0.347CS..EExtended strand (participates in β ladder)trans-112.7108.9-179.2-65.1175.9000111.1P580 I582 G620 R622P580-L600 HydrophobicContact CB-CB 4.48Å; P580-L600 HydrophobicContact CG-CD2 4.28Å; I582-L600 HydrophobicContact CB-CD2 4.08Å; I582-L600 HydrophobicContact CD1-CD2 4.23Å; I582-L600 HydrophobicContact CG1-CD2 3.65Å; I582-L600 HydrophobicContact CG2-CD2 3.83Å; L600-G620 WeakPolarHBondContact CD1-O 3.43Å; L600-R622 HydrophobicContact CB-CG 4.04Å; L600-R622 HydrophobicContact CD1-CG 3.91Å; L600-R622 PolarHBondContact O-NE 3.15Å; L600-R622 PolarHBondContact O-NH2 2.95Å
601L93.4Very high90.5Very high11 Ų1157.9 Ų57.96%0.05833%0.327CS..EExtended strand (participates in β ladder)trans-100127.1-176.4-61.2165.7000110.1I523 P580 I581 V583 L614 V633 V635I523-L601 HydrophobicContact CD1-CD1 3.37Å; P580-L601 CarbonylContact C-O 3.48Å; P580-L601 VanDerWaalsContact CA-O 3.27Å; P580-L601 WeakPolarHBondContact CA-O 3.39Å; P580-L601 WeakPolarHBondContact CB-O 3.4Å; I581-L601 HydrophobicContact CB-CB 4.22Å; I581-L601 PolarHBondContact N-O 3.42Å; I581-L601 PolarHBondContact O-N 3.15Å; V583-L601 HydrophobicContact CG2-CD1 3.71Å; L601-L614 HydrophobicContact CD2-CD1 3.37Å; L601-L614 HydrophobicContact CG-CD1 4.42Å; L601-V633 HydrophobicContact CD1-CG2 4.31Å; L601-V633 HydrophobicContact CD2-CG2 4.2Å; L601-V635 HydrophobicContact CD1-CG2 3.89Å; L601-V635 HydrophobicContact CD2-CG2 4.42Å
602A91.3Very high91.1Very high33 Ų3352 Ų5227%0.27330%0.295SS..  trans-70.9-40.7173.100000110.1R574 R622R574-A602 PolarHBondContact NH1-O 3.08Å; R574-A602 VanDerWaalsContact NH1-O 3.15Å; R574-A602 PolarHBondContact NH2-O 3.33Å; A602-R622 VanDerWaalsContact N-NH2 3.13Å
603A89.9Confident91.6Very high1 Ų151.2 Ų51.21%0.00829%0.287CS..  trans55.858.1179.400000110.7T521 R574 I581 D607 V635 S637T521-A603 HydrophobicContact CG2-CB 3.75Å; R574-A603 PolarHBondContact NH1-O 2.81Å; I581-A603 HydrophobicContact CD1-CB 4.01Å; A603-D607 VanDerWaalsContact CA-OD2 3.22Å; A603-D607 WeakPolarHBondContact CA-OD2 3.37Å; A603-D607 PolarHBondContact N-OD2 2.88Å; A603-D607 VanDerWaalsContact N-OD2 3.07Å; A603-V635 HydrophobicContact CB-CG1 3.65Å; A603-S637 WeakPolarHBondContact O-CB 3.3Å; A603-S637 PolarHBondContact O-OG 3.14Å
604S90.4Very high91.7Very high47 Ų4751.8 Ų51.833%0.32929%0.29SS..  trans-83.1150171.6-64.70000110G606 D607S604-G606 PolarHBondContact O-N 3.19Å; S604-G606 VanDerWaalsContact O-N 3.15Å; S604-D607 PolarHBondContact N-OD2 2.8Å; S604-D607 VanDerWaalsContact O-CB 3.31Å; S604-D607 WeakPolarHBondContact O-CB 3.38Å; S604-D607 PolarHBondContact O-N 3.41Å
605P88.6Confident91.8Very high41 Ų4150.6 Ų50.627%0.26628%0.284SS..THydrogen-bonded Turntrans-59.6-25.5179.1-26.734.6000114.5
606G86.5Confident91.9Very high76 Ų7648.6 Ų48.678%0.78428%0.275SS*.THydrogen-bonded Turntrans-86.9-2.217500000115S604S604-G606 PolarHBondContact O-N 3.19Å; S604-G606 VanDerWaalsContact O-N 3.15Å
607D87.3Confident92Very high57 Ų5752 Ų5231%0.30529%0.288SS..SBendtrans-64.3149.2176.1-70.8-12.2000110.1A603 S604 R609A603-D607 VanDerWaalsContact CA-OD2 3.22Å; A603-D607 WeakPolarHBondContact CA-OD2 3.37Å; A603-D607 PolarHBondContact N-OD2 2.88Å; A603-D607 VanDerWaalsContact N-OD2 3.07Å; S604-D607 PolarHBondContact N-OD2 2.8Å; S604-D607 VanDerWaalsContact O-CB 3.31Å; S604-D607 WeakPolarHBondContact O-CB 3.38Å; S604-D607 PolarHBondContact O-N 3.41Å; D607-R609 PolarHBondContact O-N 3.14Å
608P86.2Confident91.8Very high81 Ų8152.8 Ų52.853%0.52630%0.296SS..  trans-56.9130.4177.9-20.728.9000111.4E610 Q612P608-E610 VanDerWaalsContact C-N 3.26Å; P608-E610 PolarHBondContact O-N 2.97Å; P608-Q612 PolarHBondContact O-NE2 3.26Å
609R86.7Confident91.5Very high118 Ų11859.8 Ų59.845%0.44532%0.322SS..  trans-82.8-4.9-179.2-64.3-179.3-179.3-161.1-4.3113.5D607 K634 F636D607-R609 PolarHBondContact O-N 3.14Å; R609-K634 WeakPolarHBondContact O-CE 3.44Å; R609-F636 HydrophobicContact CB-CD1 4.19Å; R609-F636 HydrophobicContact CB-CE1 3.73Å; R609-F636 HydrophobicContact CB-CZ 4.36Å; R609-F636 HydrophobicContact CG-CD1 4.03Å; R609-F636 HydrophobicContact CG-CE1 4.04Å
610E88.8Confident90.7Very high155 Ų15561.8 Ų61.872%0.72434%0.343SS*.SBendtrans-75.3167.2176.4-66.1-178.7-176.400111.4P608P608-E610 VanDerWaalsContact C-N 3.26Å; P608-E610 PolarHBondContact O-N 2.97Å
611Q91.8Very high89.7Confident106 Ų10663.6 Ų63.650%0.49536%0.358SS..  trans-70.1132.1176.8-174.7171-9.700109.6T632Q611-T632 HydrophobicContact CG-CG2 3.38Å
612Q93.7Very high88.6Confident52 Ų5270 Ų7024%0.24338%0.381CS..EExtended strand (participates in β ladder)trans-121134.3-176.5-62.6178.6-6.400110.1P608 T632 V633P608-Q612 PolarHBondContact O-NE2 3.26Å; Q612-T632 CarbonylContact O-C 3.57Å; Q612-T632 VanDerWaalsContact O-CA 3.31Å; Q612-T632 WeakPolarHBondContact O-CA 3.36Å; Q612-V633 PolarHBondContact N-O 3.5Å; Q612-V633 PolarHBondContact O-N 3.45Å
613T95.3Very high88.1Confident82 Ų8276.6 Ų76.650%0.50341%0.407SS..EExtended strand (participates in β ladder)trans-104.6122.2171.7-60.50000109.3R630 I631 T632T613-R630 HydrophobicContact CG2-CB 3.75Å; T613-R630 HydrophobicContact CG2-CG 4.38Å; T613-I631 CarbonylContact C-O 3.53Å; T613-I631 WeakPolarHBondContact CA-O 3.21Å; T613-T632 WeakPolarHBondContact OG1-CG2 3.03Å; T613-T632 PolarHBondContact OG1-OG1 3.05Å
614L94.6Very high87.8Confident50 Ų5077.3 Ų77.326%0.26241%0.413SS..EExtended strand (participates in β ladder)trans-117135.6-173.8-57.9176.2000110.2A599 L601 R630 I631 V633A599-L614 HydrophobicContact CB-CB 4.33Å; A599-L614 HydrophobicContact CB-CD1 4.14Å; L601-L614 HydrophobicContact CD2-CD1 3.37Å; L601-L614 HydrophobicContact CG-CD1 4.42Å; L614-R630 CarbonylContact O-C 3.26Å; L614-R630 VanDerWaalsContact O-CA 3.28Å; L614-R630 WeakPolarHBondContact O-CA 3.45Å; L614-I631 HydrophobicContact CB-CG2 4.18Å; L614-I631 PolarHBondContact N-O 3.17Å; L614-I631 PolarHBondContact O-N 3.13Å; L614-V633 HydrophobicContact CD1-CG2 4.11Å
615Q96Very high87.7Confident54 Ų5478.8 Ų78.825%0.25243%0.428SS..EExtended strand (participates in β ladder)trans-68.1131.6172.9-171.56044.300110E626 V627 G629Q615-E626 HydrophobicContact CG-CB 4.17Å; Q615-E626 HydrophobicContact CG-CG 4.07Å; Q615-V627 PolarHBondContact NE2-O 2.53Å; Q615-G629 PolarHBondContact NE2-O 3.24Å
616L96Very high87.9Confident0 Ų082.3 Ų82.30%044%0.441CS..EExtended strand (participates in β ladder)trans-70.5144.1176-67.7177.5000110.6L531 V585 V627 G629 I631L531-L616 HydrophobicContact CD2-CD1 3.66Å; V585-L616 HydrophobicContact CB-CD1 4.3Å; V585-L616 HydrophobicContact CG2-CD1 3.96Å; V585-L616 HydrophobicContact CG2-CD2 3.87Å; L616-V627 HydrophobicContact CB-CG2 3.7Å; L616-V627 PolarHBondContact O-N 3.06Å; L616-G629 VanDerWaalsContact CB-O 3.31Å; L616-G629 WeakPolarHBondContact CB-O 3.47Å; L616-G629 WeakPolarHBondContact CG-O 2.93Å; L616-G629 PolarHBondContact N-O 3.48Å; L616-I631 HydrophobicContact CD2-CB 3.99Å; L616-I631 HydrophobicContact CD2-CG2 3.77Å
617R94.7Very high88.2Confident77 Ų7780.5 Ų80.529%0.29141%0.414SS..EExtended strand (participates in β ladder)trans-128.1162.3178.3-67.4-179.9173.6-113.9-3.7111.9G597 Q598 R622 A624 A625 E626G597-R617 CarbonylContact C-O 3.58Å; G597-R617 WeakPolarHBondContact CA-O 3.46Å; Q598-R617 PolarHBondContact N-O 3.2Å; Q598-R617 PolarHBondContact O-N 2.79Å; R617-R622 VanDerWaalsContact CD-O 3.29Å; R617-R622 WeakPolarHBondContact CD-O 3.19Å; R617-R622 PolarHBondContact NH1-O 2.57Å; R617-A624 HydrophobicContact CB-CB 4.36Å; R617-A624 WeakPolarHBondContact CD-O 3.47Å; R617-A624 PolarHBondContact NH1-O 2.92Å; R617-A625 CarbonylContact C-O 3.57Å; R617-A625 WeakPolarHBondContact CA-O 3.4Å; R617-E626 HydrophobicContact CG-CG 4.3Å; R617-E626 IonicContact CZ-OE1 3.24Å; R617-E626 IonicContact NH2-OE1 2.86Å; R617-E626 PolarHBondContact NH2-OE1 3.44Å
618G91.6Very high88.5Confident16 Ų1680.9 Ų80.917%0.16542%0.42CS..  trans-60.5175.3172.900000113.4Q598 A625Q598-G618 PolarHBondContact NE2-O 3.49Å; G618-A625 PolarHBondContact N-O 3.26Å
619R88.4Confident88.9Confident160 Ų16077.4 Ų77.460%0.60440%0.399SS*.SBendtrans-67.8139.3175.3-69.7-171-176.5-166.88.1110.6F595F595-R619 HydrophobicContact CD1-CG 4.06Å; F595-R619 HydrophobicContact CE1-CG 3.65Å; F595-R619 HydrophobicContact CE2-CG 4.21Å; F595-R619 HydrophobicContact CG-CG 4.49Å; F595-R619 HydrophobicContact CZ-CG 3.72Å
620G78.4Confident89.3Confident49 Ų4978.7 Ų78.751%0.50540%0.404SS..SBendtrans128.7-142.4175.400000112.5Q598 L600Q598-G620 PolarHBondContact NE2-O 3.18Å; L600-G620 WeakPolarHBondContact CD1-O 3.43Å
621S74.4Confident89.7Confident69 Ų6971.3 Ų71.348%0.48337%0.369SS..SBendtrans-76.1176.5-179.5720000112.4E623 A624S621-E623 PolarHBondContact O-N 2.93Å; S621-E623 VanDerWaalsContact O-N 3.16Å; S621-E623 PolarHBondContact OG-N 2.92Å; S621-A624 WeakPolarHBondContact O-CB 3.5Å; S621-A624 PolarHBondContact O-N 3.38Å; S621-A624 VanDerWaalsContact O-N 3.14Å
622R70Confident89.9Confident145 Ų14566.6 Ų66.655%0.54735%0.347SS..THydrogen-bonded Turntrans-61.3-18.4173.7-76.6-177.5168.4178.4-4.1113.6L600 A602 R617 A624L600-R622 HydrophobicContact CB-CG 4.04Å; L600-R622 HydrophobicContact CD1-CG 3.91Å; L600-R622 PolarHBondContact O-NE 3.15Å; L600-R622 PolarHBondContact O-NH2 2.95Å; A602-R622 VanDerWaalsContact N-NH2 3.13Å; R617-R622 VanDerWaalsContact CD-O 3.29Å; R617-R622 WeakPolarHBondContact CD-O 3.19Å; R617-R622 PolarHBondContact NH1-O 2.57Å; R622-A624 VanDerWaalsContact C-N 3.34Å
623E80.1Confident90Very high172 Ų17264.1 Ų64.180%0.80434%0.336SS*.THydrogen-bonded Turntrans-89.5-0.8-179.7-63.8170.5-17600112.8S621S621-E623 PolarHBondContact O-N 2.93Å; S621-E623 VanDerWaalsContact O-N 3.16Å; S621-E623 PolarHBondContact OG-N 2.92Å
624A84.1Confident89.9Confident17 Ų1763 Ų6314%0.1432%0.324CS..SBendtrans-55.9147.5173.900000111.1R617 S621 R622R617-A624 HydrophobicContact CB-CB 4.36Å; R617-A624 WeakPolarHBondContact CD-O 3.47Å; R617-A624 PolarHBondContact NH1-O 2.92Å; S621-A624 WeakPolarHBondContact O-CB 3.5Å; S621-A624 PolarHBondContact O-N 3.38Å; S621-A624 VanDerWaalsContact O-N 3.14Å; R622-A624 VanDerWaalsContact C-N 3.34Å
625A88.8Confident89.9Confident77 Ų7761.3 Ų61.364%0.63632%0.315SS*.PPolyproline II helixtrans-54.7141.3179.800000111.5R617 G618R617-A625 CarbonylContact C-O 3.57Å; R617-A625 WeakPolarHBondContact CA-O 3.4Å; G618-A625 PolarHBondContact N-O 3.26Å
626E92.3Very high89.9Confident116 Ų11659.7 Ų59.754%0.54231%0.308SS..EExtended strand (participates in β ladder)trans-66.1139174.8-61.1-169.5162.200110.1Q615 R617Q615-E626 HydrophobicContact CG-CB 4.17Å; Q615-E626 HydrophobicContact CG-CG 4.07Å; R617-E626 HydrophobicContact CG-CG 4.3Å; R617-E626 IonicContact CZ-OE1 3.24Å; R617-E626 IonicContact NH2-OE1 2.86Å; R617-E626 PolarHBondContact NH2-OE1 3.44Å
627V93.4Very high89.8Confident37 Ų3760 Ų6022%0.22431%0.31CS..EExtended strand (participates in β ladder)trans-119159.5175.6-62.60000109L596 Q615 L616 G629L596-V627 VanDerWaalsContact O-CG2 3.24Å; L596-V627 WeakPolarHBondContact O-CG2 3.29Å; Q615-V627 PolarHBondContact NE2-O 2.53Å; L616-V627 HydrophobicContact CB-CG2 3.7Å; L616-V627 PolarHBondContact O-N 3.06Å; V627-G629 PolarHBondContact O-N 3.36Å
628P92.8Very high89.8Confident65 Ų6556.7 Ų56.742%0.42230%0.299SS..EExtended strand (participates in β ladder)trans-56.4134.4179.6-26.235.4000112.6G530 Q532G530-P628 CarbonylContact O-C 3.58Å; Q532-P628 HydrophobicContact CB-CB 4.18Å; Q532-P628 HydrophobicContact CB-CG 4.33Å
629G94.4Very high90Very high8 Ų860.3 Ų60.38%0.08231%0.314CS..EExtended strand (participates in β ladder)trans107156.317200000114.8E529 G530 Q615 L616 V627E529-G629 CarbonylContact O-C 3.49Å; E529-G629 WeakPolarHBondContact O-CA 3.33Å; G530-G629 WeakPolarHBondContact O-CA 3.26Å; G530-G629 PolarHBondContact O-N 3.27Å; G530-G629 VanDerWaalsContact O-N 3.1Å; Q615-G629 PolarHBondContact NE2-O 3.24Å; L616-G629 VanDerWaalsContact CB-O 3.31Å; L616-G629 WeakPolarHBondContact CB-O 3.47Å; L616-G629 WeakPolarHBondContact CG-O 2.93Å; L616-G629 PolarHBondContact N-O 3.48Å; V627-G629 PolarHBondContact O-N 3.36Å
630R96.5Very high90.3Very high146 Ų14656.6 Ų56.655%0.55131%0.306SS*.EExtended strand (participates in β ladder)trans-126.3147.4-179.6-67.5178.3176.1-179.40.6109.1A528 E529 T613 L614A528-R630 CarbonylContact C-O 3.54Å; A528-R630 WeakPolarHBondContact CA-O 3.2Å; E529-R630 PolarHBondContact N-O 2.99Å; E529-R630 PolarHBondContact O-N 3.21Å; T613-R630 HydrophobicContact CG2-CB 3.75Å; T613-R630 HydrophobicContact CG2-CG 4.38Å; L614-R630 CarbonylContact O-C 3.26Å; L614-R630 VanDerWaalsContact O-CA 3.28Å; L614-R630 WeakPolarHBondContact O-CA 3.45Å
631I96.3Very high91Very high0 Ų054.8 Ų54.80%029%0.285CS..EExtended strand (participates in β ladder)trans-119.3133.5176-169.2163.8000110.2I525 S527 A528 V544 V583 V585 A599 T613 L614 L616 V633I525-I631 HydrophobicContact CG2-CD1 3.98Å; I525-I631 HydrophobicContact CG2-CG1 4.14Å; S527-I631 WeakPolarHBondContact O-CA 3.31Å; S527-I631 WeakPolarHBondContact O-CG1 3.2Å; A528-I631 HydrophobicContact CB-CG1 4.39Å; V544-I631 HydrophobicContact CG2-CD1 4.38Å; V583-I631 HydrophobicContact CB-CD1 4.4Å; V583-I631 HydrophobicContact CG1-CD1 3.37Å; V585-I631 HydrophobicContact CG2-CD1 3.88Å; A599-I631 HydrophobicContact CB-CG2 3.78Å; T613-I631 CarbonylContact C-O 3.53Å; T613-I631 WeakPolarHBondContact CA-O 3.21Å; L614-I631 HydrophobicContact CB-CG2 4.18Å; L614-I631 PolarHBondContact N-O 3.17Å; L614-I631 PolarHBondContact O-N 3.13Å; L616-I631 HydrophobicContact CD2-CB 3.99Å; L616-I631 HydrophobicContact CD2-CG2 3.77Å; I631-V633 HydrophobicContact CD1-CG1 4.4Å; I631-V633 HydrophobicContact CG1-CG1 3.96Å
632T96.3Very high91.9Very high6 Ų652.7 Ų52.74%0.03727%0.269CS..EExtended strand (participates in β ladder)trans-107.2122.6-179.3-55.30000109.8H526 S527 Q611 Q612 T613H526-T632 HydrophobicContact CB-CG2 4.27Å; H526-T632 PolarHBondContact N-O 3.44Å; S527-T632 PolarHBondContact N-O 3.17Å; S527-T632 PolarHBondContact O-N 2.78Å; S527-T632 PolarHBondContact OG-OG1 2.99Å; Q611-T632 HydrophobicContact CG-CG2 3.38Å; Q612-T632 CarbonylContact O-C 3.57Å; Q612-T632 VanDerWaalsContact O-CA 3.31Å; Q612-T632 WeakPolarHBondContact O-CA 3.36Å; T613-T632 WeakPolarHBondContact OG1-CG2 3.03Å; T613-T632 PolarHBondContact OG1-OG1 3.05Å
633V94.9Very high92.9Very high0 Ų048.3 Ų48.30%026%0.255CS..EExtended strand (participates in β ladder)trans-135.5157.9-171.4-55.90000111.4K524 I525 L601 Q612 L614 I631 V635K524-V633 CarbonylContact O-C 3.59Å; K524-V633 WeakPolarHBondContact O-CA 3.45Å; I525-V633 HydrophobicContact CD1-CB 4.26Å; I525-V633 HydrophobicContact CD1-CG1 3.49Å; I525-V633 VanDerWaalsContact CD1-CG1 3.49Å; L601-V633 HydrophobicContact CD1-CG2 4.31Å; L601-V633 HydrophobicContact CD2-CG2 4.2Å; Q612-V633 PolarHBondContact N-O 3.5Å; Q612-V633 PolarHBondContact O-N 3.45Å; L614-V633 HydrophobicContact CD1-CG2 4.11Å; I631-V633 HydrophobicContact CD1-CG1 4.4Å; I631-V633 HydrophobicContact CG1-CG1 3.96Å; V633-V635 HydrophobicContact CG2-CG2 4.26Å
634K94.5Very high93.2Very high60 Ų6040.3 Ų40.326%0.26122%0.218SC..EExtended strand (participates in β ladder)trans-129.7129.9169.9-164.4180-171.1-1690108.7I523 K524 R609 F636I523-K634 CarbonylContact C-O 3.59Å; I523-K634 WeakPolarHBondContact CA-O 3.44Å; K524-K634 HydrophobicContact CB-CB 4.45Å; K524-K634 PolarHBondContact N-O 2.97Å; K524-K634 PolarHBondContact O-N 2.85Å; R609-K634 WeakPolarHBondContact O-CE 3.44Å; K634-F636 HydrophobicContact CD-CE2 3.73Å; K634-F636 HydrophobicContact CD-CZ 4.19Å; K634-F636 VanDerWaalsContact CE-CZ 3.42Å; K634-F636 HydrophobicContact CG-CD2 4.5Å; K634-F636 HydrophobicContact CG-CE2 3.74Å; K634-F636 HydrophobicContact CG-CZ 4.38Å
635V94.5Very high93.7Very high13 Ų1341.5 Ų41.58%0.07922%0.221CC..EExtended strand (participates in β ladder)trans-128.7134.8-172-174.20000110T521 Q522 I523 L601 A603 V633T521-V635 HydrophobicContact CG2-CG1 3.83Å; Q522-V635 WeakPolarHBondContact O-CA 3.37Å; I523-V635 HydrophobicContact CD1-CG2 4.28Å; I523-V635 HydrophobicContact CG1-CG2 4.16Å; L601-V635 HydrophobicContact CD1-CG2 3.89Å; L601-V635 HydrophobicContact CD2-CG2 4.42Å; A603-V635 HydrophobicContact CB-CG1 3.65Å; V633-V635 HydrophobicContact CG2-CG2 4.26Å
636F94.9Very high94Very high21 Ų2139.6 Ų39.69%0.09220%0.2CC..EExtended strand (participates in β ladder)trans-128.5130.7172.2-66.8-93000108.8T443 V444 T521 Q522 R609 K634 L644T443-F636 HydrophobicContact CG2-CD1 4.4Å; V444-F636 HydrophobicContact CG1-CD2 3.57Å; V444-F636 HydrophobicContact CG1-CE2 3.43Å; V444-F636 VanDerWaalsContact CG1-CE2 3.43Å; T521-F636 CarbonylContact C-O 3.57Å; T521-F636 VanDerWaalsContact CA-O 3.25Å; T521-F636 WeakPolarHBondContact CA-O 3.41Å; Q522-F636 HydrophobicContact CB-CB 4.36Å; Q522-F636 PolarHBondContact N-O 3.31Å; Q522-F636 PolarHBondContact O-N 3.22Å; R609-F636 HydrophobicContact CB-CD1 4.19Å; R609-F636 HydrophobicContact CB-CE1 3.73Å; R609-F636 HydrophobicContact CB-CZ 4.36Å; R609-F636 HydrophobicContact CG-CD1 4.03Å; R609-F636 HydrophobicContact CG-CE1 4.04Å; K634-F636 HydrophobicContact CD-CE2 3.73Å; K634-F636 HydrophobicContact CD-CZ 4.19Å; K634-F636 VanDerWaalsContact CE-CZ 3.42Å; K634-F636 HydrophobicContact CG-CD2 4.5Å; K634-F636 HydrophobicContact CG-CE2 3.74Å; K634-F636 HydrophobicContact CG-CZ 4.38Å; F636-L644 HydrophobicContact CB-CD1 4.23Å; F636-L644 HydrophobicContact CB-CD2 4.41Å
637S95.2Very high94Very high6 Ų635.3 Ų35.34%0.04218%0.181CC..EExtended strand (participates in β ladder)trans-131.3143.6175.2-62.40000111.1V520 T521 A603V520-S637 CarbonylContact O-C 3.51Å; V520-S637 VanDerWaalsContact O-CA 3.27Å; V520-S637 WeakPolarHBondContact O-CA 3.48Å; T521-S637 WeakPolarHBondContact CB-OG 3.44Å; T521-S637 VanDerWaalsContact CG2-OG 3.25Å; T521-S637 WeakPolarHBondContact CG2-OG 3.41Å; T521-S637 PolarHBondContact OG1-OG 3.11Å; A603-S637 WeakPolarHBondContact O-CB 3.3Å; A603-S637 PolarHBondContact O-OG 3.14Å
638S95.1Very high94.1Very high8 Ų835.2 Ų35.26%0.05618%0.178CC..EExtended strand (participates in β ladder)trans-139.4143.7173.9-174.20000110.9R519 V520 D640 E643R519-S638 CarbonylContact C-O 3.52Å; R519-S638 VanDerWaalsContact CA-O 3.31Å; R519-S638 WeakPolarHBondContact CA-O 3.48Å; R519-S638 WeakPolarHBondContact CG-O 3.26Å; V520-S638 PolarHBondContact N-O 2.81Å; V520-S638 PolarHBondContact O-N 3.27Å; S638-D640 VanDerWaalsContact C-N 3.27Å; S638-D640 PolarHBondContact OG-N 3.02Å; S638-D640 PolarHBondContact OG-O 2.88Å; S638-E643 WeakPolarHBondContact CB-OE2 3.41Å; S638-E643 PolarHBondContact OG-OE2 2.99Å
639D95.3Very high94.2Very high92 Ų9233.4 Ų33.449%0.49216%0.163SC..SBendtrans-81.4-12.5169.7-65-21.7000111.4R519R519-D639 IonicContact CZ-OD1 2.8Å; R519-D639 VanDerWaalsContact CZ-OD1 3.24Å; R519-D639 IonicContact NE-OD1 3.75Å; R519-D639 PolarHBondContact NE-OD1 2.84Å; R519-D639 IonicContact NH2-OD1 3.88Å; R519-D639 PolarHBondContact NH2-OD1 2.85Å; R519-D639 IonicContact NH2-OD2 3.19Å; R519-D639 PolarHBondContact NH2-OD2 2.98Å
640D94.4Very high94.1Very high81 Ų8135.1 Ų35.143%0.43317%0.168SC..SBendtrans-87111.3165.5-177.25.8000110.5V520 S638 V642 E643V520-D640 VanDerWaalsContact CG1-O 3.32Å; V520-D640 WeakPolarHBondContact CG1-O 3.49Å; S638-D640 VanDerWaalsContact C-N 3.27Å; S638-D640 PolarHBondContact OG-N 3.02Å; S638-D640 PolarHBondContact OG-O 2.88Å; D640-V642 PolarHBondContact O-N 2.57Å; D640-V642 VanDerWaalsContact O-N 3.09Å; D640-V642 WeakPolarHBondContact OD1-CG2 3.26Å; D640-V642 PolarHBondContact OD1-N 2.76Å; D640-E643 HydrophobicContact CB-CB 4.22Å; D640-E643 PolarHBondContact O-N 3.39Å; D640-E643 VanDerWaalsContact O-N 3.08Å
641L93.9Very high94Very high11 Ų1127.1 Ų27.16%0.05814%0.141CC..THydrogen-bonded Turntrans-65.5-11.2-178.1-58.4-173.7000114.1K504 Y516 P517 V520 Y573K504-L641 HydrophobicContact CB-CB 4.14Å; K504-L641 HydrophobicContact CD-CB 3.97Å; K504-L641 HydrophobicContact CD-CD1 4.23Å; Y516-L641 HydrophobicContact CD1-CD1 4.48Å; Y516-L641 HydrophobicContact CE1-CD1 3.56Å; P517-L641 HydrophobicContact CB-CD1 4.13Å; P517-L641 HydrophobicContact CB-CD2 4.35Å; P517-L641 WeakPolarHBondContact O-CD1 3.06Å; V520-L641 HydrophobicContact CB-CD2 4.27Å; Y573-L641 HydrophobicContact CD1-CB 4.49Å; Y573-L641 HydrophobicContact CD1-CD2 4.18Å; Y573-L641 HydrophobicContact CE1-CB 4.26Å
642V93.1Very high93.8Very high26 Ų2629.2 Ų29.216%0.15815%0.152CC..THydrogen-bonded Turntrans-109.916.7175.2-59.50000113H440 D503 K504 D640H440-V642 WeakPolarHBondContact CB-O 3.26Å; H440-V642 PolarHBondContact CD2-O 2.91Å; D503-V642 HydrophobicContact CB-CG1 3.88Å; K504-V642 HydrophobicContact CB-CG1 4.25Å; K504-V642 HydrophobicContact CD-CG1 4.04Å; K504-V642 HydrophobicContact CG-CG1 4.31Å; D640-V642 PolarHBondContact O-N 2.57Å; D640-V642 VanDerWaalsContact O-N 3.09Å; D640-V642 WeakPolarHBondContact OD1-CG2 3.26Å; D640-V642 PolarHBondContact OD1-N 2.76Å
643E90Very high93.6Very high52 Ų5231.2 Ų31.224%0.24316%0.161CC..  trans-82.8-24175.3-156.6-164.3147.900113.4K441 S638 D640K441-E643 WeakPolarHBondContact CB-O 3.33Å; K441-E643 HydrophobicContact CD-CG 4.46Å; K441-E643 WeakPolarHBondContact CD-O 3.15Å; K441-E643 IonicContact NZ-OE1 3.44Å; K441-E643 PolarHBondContact NZ-OE1 2.87Å; S638-E643 WeakPolarHBondContact CB-OE2 3.41Å; S638-E643 PolarHBondContact OG-OE2 2.99Å; D640-E643 HydrophobicContact CB-CB 4.22Å; D640-E643 PolarHBondContact O-N 3.39Å; D640-E643 VanDerWaalsContact O-N 3.08Å
644L87.3Confident93.5Very high4 Ų434 Ų342%0.02118%0.176CC..  trans-117.90-164.5-62.8-170.3000116.2R435 T443 V520 Q522 F636R435-L644 PolarHBondContact NH2-OXT 2.81Å; T443-L644 HydrophobicContact CG2-CD2 4.25Å; V520-L644 HydrophobicContact CG1-CB 4.05Å; V520-L644 HydrophobicContact CG1-CD1 3.9Å; V520-L644 HydrophobicContact CG1-CG 3.93Å; V520-L644 HydrophobicContact CG2-CB 4.15Å; V520-L644 HydrophobicContact CG2-CD1 4.32Å; Q522-L644 HydrophobicContact CB-CD1 4.38Å; Q522-L644 HydrophobicContact CG-CB 4.15Å; Q522-L644 HydrophobicContact CG-CD1 4.02Å; Q522-L644 PolarHBondContact NE2-OXT 3.21Å; F636-L644 HydrophobicContact CB-CD1 4.23Å; F636-L644 HydrophobicContact CB-CD2 4.41Å

Retrieved 644 of 644 residues in 211.1 ms (Link to these results)