A0A093HVN3_STRCA Loading...

Sphingomyelin phosphodiesterase 3

AlphaFold DB , UniProt , Accession A0A093HVN3, Species STRCA (Struthio camelus australis), Gene n/a, Length 662 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M63.9Low89.5Confident117 Ų11767.4 Ų67.458%0.57639%0.39SS*.  0165.80-67.6-177.6178.400109.1D422 A424 F491 T495M1-D422 WeakPolarHBondContact CA-OD1 3.47Å; M1-D422 HydrophobicContact CB-CB 4.44Å; M1-D422 VanDerWaalsContact CB-OD1 3.22Å; M1-D422 WeakPolarHBondContact CB-OD1 3.27Å; M1-D422 WeakPolarHBondContact CG-OD1 3.34Å; M1-D422 PolarHBondContact N-OD1 3.13Å; M1-D422 HydrophobicContact SD-CB 4.47Å; M1-A424 HydrophobicContact SD-CB 4.47Å; M1-F491 HydrophobicContact CE-CD2 4.43Å; M1-F491 HydrophobicContact CE-CE2 4.37Å; M1-F491 HydrophobicContact SD-CE2 4.31Å; M1-T495 HydrophobicContact CE-CG2 4.05Å; M1-T495 HydrophobicContact SD-CG2 4.45Å
2V82.9Confident90Very high107 Ų10773.6 Ų73.665%0.64841%0.41SS*.  trans-97.8124.3175.4178.70000109.3
3L92.8Very high90.4Very high33 Ų3370.3 Ų70.317%0.17339%0.391CS..  trans-78.4131173.5-65176.4000110.8Y95 Y97 I420 A423L3-Y95 HydrophobicContact CD2-CE2 4.34Å; L3-Y97 HydrophobicContact CB-CD1 3.89Å; L3-Y97 HydrophobicContact CB-CE1 4.47Å; L3-Y97 HydrophobicContact CB-CG 4.04Å; L3-Y97 HydrophobicContact CD1-CD1 4.17Å; L3-Y97 HydrophobicContact CD1-CD2 4.18Å; L3-Y97 HydrophobicContact CD1-CE1 4.1Å; L3-Y97 HydrophobicContact CD1-CE2 4.1Å; L3-Y97 HydrophobicContact CD1-CG 4.2Å; L3-I420 HydrophobicContact CD1-CB 4.24Å; L3-I420 HydrophobicContact CD1-CG2 4.28Å; L3-I420 VanDerWaalsContact CD1-O 3.26Å; L3-I420 WeakPolarHBondContact CD1-O 3.29Å; L3-I420 HydrophobicContact CD2-CG2 4.16Å; L3-A423 HydrophobicContact CD2-CB 3.89Å
4Y93.6Very high90.7Very high71 Ų7167.2 Ų67.228%0.27838%0.376SS..  trans-91.5109.3-172.6-60.1-53.5000112.9R93 P94 Y95 I96 Y97Y4-R93 HydrophobicContact CD1-CG 3.98Å; Y4-R93 HydrophobicContact CD2-CB 4.06Å; Y4-R93 HydrophobicContact CD2-CG 4.32Å; Y4-R93 HydrophobicContact CE1-CG 4.29Å; Y4-R93 HydrophobicContact CG-CB 4.02Å; Y4-R93 HydrophobicContact CG-CG 3.99Å; Y4-P94 HydrophobicContact CD2-CG 4.41Å; Y4-P94 HydrophobicContact CE2-CG 4.13Å; Y4-Y95 HydrophobicContact CD2-CD1 4.45Å; Y4-Y95 HydrophobicContact CD2-CD2 4.25Å; Y4-Y95 AromaticContact CD2-CE1 3.97Å; Y4-Y95 HydrophobicContact CD2-CE1 3.97Å; Y4-Y95 AromaticContact CD2-CE2 3.74Å; Y4-Y95 HydrophobicContact CD2-CE2 3.74Å; Y4-Y95 AromaticContact CD2-CZ 3.58Å; Y4-Y95 HydrophobicContact CE2-CE1 4.19Å; Y4-Y95 HydrophobicContact CG-CE2 4.35Å; Y4-I96 CarbonylContact O-C 3.11Å; Y4-I96 WeakPolarHBondContact O-CA 3.44Å; Y4-Y97 PolarHBondContact O-N 3.02Å
5T93.8Very high91Very high105 Ų10570.6 Ų70.664%0.64439%0.391SS*.SBendtrans-85.2-7.417854.60000115.1Y97T5-Y97 WeakPolarHBondContact CA-O 3.45Å; T5-Y97 HydrophobicContact CG2-CD1 3.96Å
6S92.8Very high91.3Very high35 Ų3569.1 Ų69.125%0.24538%0.382CS..SBendtrans-135.1143.7179.9165.20000109.5F8 R93S6-F8 PolarHBondContact O-N 3.21Å; S6-F8 PolarHBondContact OG-N 3.17Å; S6-F8 PolarHBondContact OG-O 3.19Å; S6-R93 WeakPolarHBondContact O-CD 3.33Å; S6-R93 PolarHBondContact O-NH1 3.47Å
7P92.2Very high91.5Very high31 Ų3166.5 Ų66.520%0.20137%0.366CS..SBendtrans-63.4-24.5178.124.6-33.8000113.6R92 R93 I96P7-R92 VanDerWaalsContact CB-NH1 3.26Å; P7-R93 PolarHBondContact O-N 2.6Å; P7-I96 HydrophobicContact CB-CD1 4Å; P7-I96 HydrophobicContact CB-CG1 4.24Å; P7-I96 HydrophobicContact CG-CD1 4.19Å
8F94.3Very high91.7Very high2 Ų267.1 Ų67.11%0.00938%0.376CS..SBendtrans-126153.9-179.6-62.8-78000111.5S6 N10 L13 H17 L88 R92S6-F8 PolarHBondContact O-N 3.21Å; S6-F8 PolarHBondContact OG-N 3.17Å; S6-F8 PolarHBondContact OG-O 3.19Å; F8-N10 VanDerWaalsContact C-N 3.28Å; F8-N10 PolarHBondContact O-N 3.4Å; F8-L13 HydrophobicContact CB-CB 3.8Å; F8-L13 HydrophobicContact CD1-CB 4.01Å; F8-L13 HydrophobicContact CG-CB 3.93Å; F8-H17 HydrophobicContact CD2-CB 4.25Å; F8-H17 HydrophobicContact CE2-CB 3.44Å; F8-H17 VanDerWaalsContact CE2-CB 3.44Å; F8-H17 AromaticContact CE2-CD2 3.7Å; F8-H17 AromaticContact CE2-CG 3.41Å; F8-H17 VanDerWaalsContact CE2-CG 3.41Å; F8-H17 AromaticContact CE2-ND1 3.95Å; F8-H17 HydrophobicContact CZ-CB 3.77Å; F8-H17 AromaticContact CZ-CD2 3.54Å; F8-H17 AromaticContact CZ-CG 3.7Å; F8-L88 HydrophobicContact CE1-CB 4.16Å; F8-L88 WeakPolarHBondContact CE1-O 3.39Å; F8-L88 HydrophobicContact CZ-CB 4.43Å; F8-R92 HydrophobicContact CD1-CB 4.39Å; F8-R92 HydrophobicContact CE1-CB 3.72Å; F8-R92 HydrophobicContact CE1-CG 4.16Å; F8-R92 HydrophobicContact CZ-CB 4.19Å; F8-R92 HydrophobicContact CZ-CG 4.23Å
9P92Very high92Very high73 Ų7369.7 Ų69.747%0.47438%0.384SS..SBendtrans-70.4-19-178.327.5-35.6000114.2L13 A91P9-L13 HydrophobicContact CG-CD1 3.96Å; P9-A91 WeakPolarHBondContact CD-O 3.36Å
10N93.3Very high92.2Very high76 Ų7666.3 Ų66.341%0.40636%0.364SS..SBendtrans-143.2158.5178.265.159.6000111.8F8 F12 L13 S14F8-N10 VanDerWaalsContact C-N 3.28Å; F8-N10 PolarHBondContact O-N 3.4Å; N10-F12 VanDerWaalsContact C-N 3.31Å; N10-F12 PolarHBondContact O-N 2.84Å; N10-F12 PolarHBondContact OD1-N 3.49Å; N10-L13 PolarHBondContact O-N 3.49Å; N10-L13 WeakPolarHBondContact OD1-CG 3.48Å; N10-L13 PolarHBondContact OD1-N 2.6Å; N10-S14 PolarHBondContact O-N 3.18Å
11S93.6Very high92.3Very high91 Ų9166.2 Ų66.264%0.63636%0.359SS*.Hα-helixtrans-66.7-29.6-176.3-52.20000113.6S14 I15S11-S14 WeakPolarHBondContact O-CB 3.42Å; S11-S14 PolarHBondContact O-N 2.78Å; S11-I15 VanDerWaalsContact O-CG1 3.3Å; S11-I15 WeakPolarHBondContact O-CG1 3.49Å; S11-I15 PolarHBondContact O-N 3.23Å
12F95.4Very high93.9Very high142 Ų14263 Ų6362%0.62336%0.356SS*.Hα-helixtrans-61.5-48178.2174.2-99.1000111.4N10 S14 I15 L16N10-F12 VanDerWaalsContact C-N 3.31Å; N10-F12 PolarHBondContact O-N 2.84Å; N10-F12 PolarHBondContact OD1-N 3.49Å; F12-S14 VanDerWaalsContact C-N 3.3Å; F12-S14 PolarHBondContact O-N 3.05Å; F12-I15 PolarHBondContact O-N 3.07Å; F12-L16 HydrophobicContact CE1-CD2 4.18Å; F12-L16 HydrophobicContact CZ-CD2 4.35Å; F12-L16 WeakPolarHBondContact O-CB 3.34Å; F12-L16 PolarHBondContact O-N 3.24Å
13L95.3Very high94.6Very high31 Ų3159.6 Ų59.616%0.16233%0.333CS..Hα-helixtrans-62.8-38176-67.4175.5000111.7F8 P9 N10 L16 H17 L88 A91F8-L13 HydrophobicContact CB-CB 3.8Å; F8-L13 HydrophobicContact CD1-CB 4.01Å; F8-L13 HydrophobicContact CG-CB 3.93Å; P9-L13 HydrophobicContact CG-CD1 3.96Å; N10-L13 PolarHBondContact O-N 3.49Å; N10-L13 WeakPolarHBondContact OD1-CG 3.48Å; N10-L13 PolarHBondContact OD1-N 2.6Å; L13-L16 PolarHBondContact O-N 3.29Å; L13-H17 VanDerWaalsContact O-CB 3.28Å; L13-H17 WeakPolarHBondContact O-CB 3.3Å; L13-H17 PolarHBondContact O-N 2.93Å; L13-L88 HydrophobicContact CD2-CD2 3.55Å; L13-A91 HydrophobicContact CD1-CB 4.02Å
14S93.6Very high94.8Very high27 Ų2759.2 Ų59.219%0.18933%0.331CS..Hα-helixtrans-62.8-44.7174.3-640000112.4N10 S11 F12 H17 S18N10-S14 PolarHBondContact O-N 3.18Å; S11-S14 WeakPolarHBondContact O-CB 3.42Å; S11-S14 PolarHBondContact O-N 2.78Å; F12-S14 VanDerWaalsContact C-N 3.3Å; F12-S14 PolarHBondContact O-N 3.05Å; S14-H17 PolarHBondContact O-N 2.84Å; S14-S18 PolarHBondContact O-N 3.17Å; S14-S18 PolarHBondContact O-OG 3.11Å; S14-S18 VanDerWaalsContact O-OG 3.11Å
15I95.8Very high94.9Very high118 Ų11859.1 Ų59.161%0.60533%0.333SS*.Hα-helixtrans-63.9-45.3177.3-68.8164.3000110.3S11 F12 H17 S18 F19S11-I15 VanDerWaalsContact O-CG1 3.3Å; S11-I15 WeakPolarHBondContact O-CG1 3.49Å; S11-I15 PolarHBondContact O-N 3.23Å; F12-I15 PolarHBondContact O-N 3.07Å; I15-H17 VanDerWaalsContact C-N 3.31Å; I15-H17 PolarHBondContact O-N 3.18Å; I15-S18 PolarHBondContact O-N 3.34Å; I15-F19 WeakPolarHBondContact O-CB 3.31Å; I15-F19 PolarHBondContact O-N 2.88Å
16L96.4Very high95Very high47 Ų4756.3 Ų56.325%0.24632%0.316CS..Hα-helixtrans-64.2-38.1179.1-171.755.6000111.5F12 L13 F19 S20 L88F12-L16 HydrophobicContact CE1-CD2 4.18Å; F12-L16 HydrophobicContact CZ-CD2 4.35Å; F12-L16 WeakPolarHBondContact O-CB 3.34Å; F12-L16 PolarHBondContact O-N 3.24Å; L13-L16 PolarHBondContact O-N 3.29Å; L16-F19 PolarHBondContact O-N 2.92Å; L16-S20 WeakPolarHBondContact O-CB 3.46Å; L16-S20 PolarHBondContact O-N 2.71Å; L16-S20 PolarHBondContact O-OG 2.68Å; L16-L88 HydrophobicContact CB-CD1 4.28Å; L16-L88 HydrophobicContact CD2-CD2 3.97Å; L16-L88 HydrophobicContact CG-CD1 4.02Å; L16-L88 HydrophobicContact CG-CD2 4.32Å
17H94.4Very high95.2Very high24 Ų2455.5 Ų55.511%0.11131%0.31CS..Hα-helixtrans-62.4-47.6172.5172.9-91000111.8F8 L13 S14 I15 F19 S20 W21 W85 L88F8-H17 HydrophobicContact CD2-CB 4.25Å; F8-H17 HydrophobicContact CE2-CB 3.44Å; F8-H17 VanDerWaalsContact CE2-CB 3.44Å; F8-H17 AromaticContact CE2-CD2 3.7Å; F8-H17 AromaticContact CE2-CG 3.41Å; F8-H17 VanDerWaalsContact CE2-CG 3.41Å; F8-H17 AromaticContact CE2-ND1 3.95Å; F8-H17 HydrophobicContact CZ-CB 3.77Å; F8-H17 AromaticContact CZ-CD2 3.54Å; F8-H17 AromaticContact CZ-CG 3.7Å; L13-H17 VanDerWaalsContact O-CB 3.28Å; L13-H17 WeakPolarHBondContact O-CB 3.3Å; L13-H17 PolarHBondContact O-N 2.93Å; S14-H17 PolarHBondContact O-N 2.84Å; I15-H17 VanDerWaalsContact C-N 3.31Å; I15-H17 PolarHBondContact O-N 3.18Å; H17-F19 VanDerWaalsContact C-N 3.35Å; H17-F19 PolarHBondContact O-N 3.3Å; H17-S20 PolarHBondContact O-N 3Å; H17-W21 AromaticContact CE1-CD1 3.5Å; H17-W21 VanDerWaalsContact CE1-CD1 3.5Å; H17-W21 AromaticContact NE2-CD1 3.47Å; H17-W21 AromaticContact NE2-NE1 3.92Å; H17-W21 PolarHBondContact O-N 3.28Å; H17-W85 AromaticContact CD2-CD1 3.63Å; H17-W85 AromaticContact CD2-NE1 3.75Å; H17-W85 AromaticContact NE2-CD1 3.81Å; H17-W85 AromaticContact NE2-NE1 3.53Å; H17-L88 HydrophobicContact CB-CD1 3.94Å
18S95.1Very high95.3Very high78 Ų7856.9 Ų56.955%0.54531%0.312SS..Hα-helixtrans-61.3-42.5177.4-64.60000112.1S14 I15 W21 G22S14-S18 PolarHBondContact O-N 3.17Å; S14-S18 PolarHBondContact O-OG 3.11Å; S14-S18 VanDerWaalsContact O-OG 3.11Å; I15-S18 PolarHBondContact O-N 3.34Å; S18-W21 PolarHBondContact O-N 3.03Å; S18-G22 PolarHBondContact O-N 3.47Å
19F96.9Very high95.4Very high117 Ų11760.7 Ų60.751%0.51333%0.326SS..Hα-helixtrans-61.3-46.3174.3178-101.6000111.7I15 L16 H17 W21 G22 L23 L84I15-F19 WeakPolarHBondContact O-CB 3.31Å; I15-F19 PolarHBondContact O-N 2.88Å; L16-F19 PolarHBondContact O-N 2.92Å; H17-F19 VanDerWaalsContact C-N 3.35Å; H17-F19 PolarHBondContact O-N 3.3Å; F19-W21 VanDerWaalsContact C-N 3.34Å; F19-W21 PolarHBondContact O-N 3.45Å; F19-G22 WeakPolarHBondContact O-CA 3.47Å; F19-G22 PolarHBondContact O-N 2.75Å; F19-G22 VanDerWaalsContact O-N 3.1Å; F19-L23 HydrophobicContact CD1-CD1 4.31Å; F19-L23 HydrophobicContact CE1-CD1 3.71Å; F19-L23 HydrophobicContact CE1-CG 4.43Å; F19-L23 HydrophobicContact CZ-CD1 4.03Å; F19-L23 HydrophobicContact CZ-CG 4.45Å; F19-L23 PolarHBondContact O-N 2.64Å; F19-L84 HydrophobicContact CD1-CD1 4.05Å; F19-L84 HydrophobicContact CE1-CD1 3.91Å
20S96.4Very high95.6Very high0 Ų059.2 Ų59.20%031%0.312CS..Hα-helixtrans-60.6-44178.2-54.20000111.7L16 H17 G22 L23 I24 L84L16-S20 WeakPolarHBondContact O-CB 3.46Å; L16-S20 PolarHBondContact O-N 2.71Å; L16-S20 PolarHBondContact O-OG 2.68Å; H17-S20 PolarHBondContact O-N 3Å; S20-G22 VanDerWaalsContact C-N 3.34Å; S20-L23 PolarHBondContact O-N 3.44Å; S20-I24 WeakPolarHBondContact O-CG1 3.3Å; S20-I24 PolarHBondContact O-N 3.03Å; S20-I24 VanDerWaalsContact O-N 3.08Å; S20-L84 WeakPolarHBondContact OG-CB 3.35Å
21W94.7Very high95.6Very high66 Ų6657.3 Ų57.325%0.2531%0.307CS..Hα-helixtrans-66.3-34.8174.4-111.4112.4000112.3H17 S18 F19 L23 I24 F25 Y28 W85H17-W21 AromaticContact CE1-CD1 3.5Å; H17-W21 VanDerWaalsContact CE1-CD1 3.5Å; H17-W21 AromaticContact NE2-CD1 3.47Å; H17-W21 AromaticContact NE2-NE1 3.92Å; H17-W21 PolarHBondContact O-N 3.28Å; S18-W21 PolarHBondContact O-N 3.03Å; F19-W21 VanDerWaalsContact C-N 3.34Å; F19-W21 PolarHBondContact O-N 3.45Å; W21-L23 PolarHBondContact O-N 3.46Å; W21-I24 HydrophobicContact CE3-CB 4.1Å; W21-I24 HydrophobicContact CE3-CG2 4.08Å; W21-I24 HydrophobicContact CH2-CG2 4.37Å; W21-I24 HydrophobicContact CZ3-CB 4.39Å; W21-I24 HydrophobicContact CZ3-CG2 3.88Å; W21-I24 PolarHBondContact O-N 3.46Å; W21-F25 HydrophobicContact CE3-CB 3.87Å; W21-F25 HydrophobicContact CE3-CD2 4.38Å; W21-F25 HydrophobicContact CZ3-CB 4.18Å; W21-F25 HydrophobicContact CZ3-CD2 4.16Å; W21-F25 WeakPolarHBondContact O-CA 3.24Å; W21-F25 WeakPolarHBondContact O-CB 3.13Å; W21-F25 PolarHBondContact O-N 2.97Å; W21-Y28 HydrophobicContact CH2-CD1 4.38Å; W21-Y28 HydrophobicContact CH2-CG 4.34Å; W21-Y28 HydrophobicContact CZ3-CD1 4.22Å; W21-Y28 HydrophobicContact CZ3-CG 4.32Å; W21-W85 AromaticContact CD1-CD1 3.9Å; W21-W85 AromaticContact CD1-NE1 3.84Å; W21-W85 AromaticContact NE1-NE1 3.61Å
22G96.8Very high95.7Very high49 Ų4953.2 Ų53.251%0.50528%0.278SS..Hα-helixtrans-57-33.3172.600000113.1S18 F19 S20 P26S18-G22 PolarHBondContact O-N 3.47Å; F19-G22 WeakPolarHBondContact O-CA 3.47Å; F19-G22 PolarHBondContact O-N 2.75Å; F19-G22 VanDerWaalsContact O-N 3.1Å; S20-G22 VanDerWaalsContact C-N 3.34Å; G22-P26 VanDerWaalsContact O-CD 3.31Å; G22-P26 WeakPolarHBondContact O-CD 3.39Å
23L97.6Very high95.5Very high35 Ų3549.1 Ų49.118%0.18326%0.258CS..Hα-helixtrans-79.8-37.3175.1-62.9176.4000113.3F19 S20 W21 F77 A78 I80 L84F19-L23 HydrophobicContact CD1-CD1 4.31Å; F19-L23 HydrophobicContact CE1-CD1 3.71Å; F19-L23 HydrophobicContact CE1-CG 4.43Å; F19-L23 HydrophobicContact CZ-CD1 4.03Å; F19-L23 HydrophobicContact CZ-CG 4.45Å; F19-L23 PolarHBondContact O-N 2.64Å; S20-L23 PolarHBondContact O-N 3.44Å; W21-L23 PolarHBondContact O-N 3.46Å; L23-F77 WeakPolarHBondContact CB-O 3.42Å; L23-F77 HydrophobicContact CD2-CB 4.37Å; L23-F77 HydrophobicContact CD2-CD1 4.43Å; L23-A78 PolarHBondContact O-N 2.99Å; L23-I80 HydrophobicContact CD1-CB 4.49Å; L23-I80 HydrophobicContact CD1-CG2 4.03Å; L23-L84 HydrophobicContact CD1-CD1 4.42Å
24I96.3Very high95.4Very high25 Ų2548.9 Ų48.913%0.12826%0.257CS..Hα-helixtrans-75-38.7-179.7-65.2165.8000111.6S20 W21 C27 Y28 W85S20-I24 WeakPolarHBondContact O-CG1 3.3Å; S20-I24 PolarHBondContact O-N 3.03Å; S20-I24 VanDerWaalsContact O-N 3.08Å; W21-I24 HydrophobicContact CE3-CB 4.1Å; W21-I24 HydrophobicContact CE3-CG2 4.08Å; W21-I24 HydrophobicContact CH2-CG2 4.37Å; W21-I24 HydrophobicContact CZ3-CB 4.39Å; W21-I24 HydrophobicContact CZ3-CG2 3.88Å; W21-I24 PolarHBondContact O-N 3.46Å; I24-C27 PolarHBondContact O-N 2.83Å; I24-Y28 PolarHBondContact O-N 3.45Å; I24-Y28 VanDerWaalsContact O-N 3.13Å; I24-W85 HydrophobicContact CD1-CB 3.7Å; I24-W85 HydrophobicContact CD1-CD2 4.41Å; I24-W85 HydrophobicContact CD1-CG 3.94Å
25F95.8Very high95.4Very high70 Ų7050.6 Ų50.631%0.30727%0.267SS..Hα-helixtrans-56.2-45.1-166178.2-101.6000114.3W21 C27 Y28 W29 R374W21-F25 HydrophobicContact CE3-CB 3.87Å; W21-F25 HydrophobicContact CE3-CD2 4.38Å; W21-F25 HydrophobicContact CZ3-CB 4.18Å; W21-F25 HydrophobicContact CZ3-CD2 4.16Å; W21-F25 WeakPolarHBondContact O-CA 3.24Å; W21-F25 WeakPolarHBondContact O-CB 3.13Å; W21-F25 PolarHBondContact O-N 2.97Å; F25-C27 VanDerWaalsContact C-N 3.34Å; F25-C27 PolarHBondContact O-N 2.62Å; F25-Y28 HydrophobicContact CD2-CD1 4.12Å; F25-Y28 HydrophobicContact CE2-CD1 4.23Å; F25-Y28 HydrophobicContact CE2-CE1 4.47Å; F25-Y28 PolarHBondContact O-N 3.12Å; F25-W29 HydrophobicContact CE1-CB 4.26Å; F25-W29 HydrophobicContact CE2-CB 4.43Å; F25-W29 HydrophobicContact CE2-CE3 4.22Å; F25-W29 HydrophobicContact CZ-CB 4.09Å; F25-W29 HydrophobicContact CZ-CD2 4.05Å; F25-W29 AromaticContact CZ-CE3 3.73Å; F25-W29 HydrophobicContact CZ-CE3 3.73Å; F25-W29 HydrophobicContact CZ-CG 4.27Å; F25-W29 HydrophobicContact CZ-CZ3 4.5Å; F25-W29 WeakPolarHBondContact O-CB 3.22Å; F25-W29 PolarHBondContact O-N 3.01Å; F25-R374 VanDerWaalsContact CE2-NH1 3.31Å
26P96.8Very high95.1Very high46 Ų4645.3 Ų45.330%0.29924%0.24SC..Hα-helixtrans-57.8-45.9178.8-25.735.7000112.5G22 Y28 W29 F30G22-P26 VanDerWaalsContact O-CD 3.31Å; G22-P26 WeakPolarHBondContact O-CD 3.39Å; P26-Y28 PolarHBondContact O-N 3.24Å; P26-W29 PolarHBondContact O-N 2.93Å; P26-F30 HydrophobicContact CB-CD2 4.41Å; P26-F30 HydrophobicContact CB-CE2 3.94Å; P26-F30 WeakPolarHBondContact O-CD2 3.1Å; P26-F30 VanDerWaalsContact O-CG 3.29Å; P26-F30 WeakPolarHBondContact O-CG 3.41Å; P26-F30 PolarHBondContact O-N 2.92Å
27C96.9Very high94.7Very high17 Ų1744.5 Ų44.512%0.11524%0.239CC..Hα-helixtrans-62.5-45.6178.4-179.20000111.7I24 F25 A31 L71 S74 A78I24-C27 PolarHBondContact O-N 2.83Å; F25-C27 VanDerWaalsContact C-N 3.34Å; F25-C27 PolarHBondContact O-N 2.62Å; C27-A31 WeakPolarHBondContact O-CB 3.42Å; C27-A31 PolarHBondContact O-N 3.45Å; C27-L71 WeakPolarHBondContact O-CD1 3.5Å; C27-L71 VanDerWaalsContact SG-CD1 3.56Å; C27-S74 VanDerWaalsContact CA-OG 3.29Å; C27-S74 WeakPolarHBondContact CA-OG 3.4Å; C27-A78 HydrophobicContact CB-CB 3.46Å; C27-A78 VanDerWaalsContact CB-CB 3.46Å
28Y94.7Very high94.4Very high61 Ų6149 Ų4924%0.23926%0.258CS..Hα-helixtrans-59-47.2175.1161.9-100.3000111.7W21 I24 F25 P26 A31 D32 P135 D372W21-Y28 HydrophobicContact CH2-CD1 4.38Å; W21-Y28 HydrophobicContact CH2-CG 4.34Å; W21-Y28 HydrophobicContact CZ3-CD1 4.22Å; W21-Y28 HydrophobicContact CZ3-CG 4.32Å; I24-Y28 PolarHBondContact O-N 3.45Å; I24-Y28 VanDerWaalsContact O-N 3.13Å; F25-Y28 HydrophobicContact CD2-CD1 4.12Å; F25-Y28 HydrophobicContact CE2-CD1 4.23Å; F25-Y28 HydrophobicContact CE2-CE1 4.47Å; F25-Y28 PolarHBondContact O-N 3.12Å; P26-Y28 PolarHBondContact O-N 3.24Å; Y28-A31 PolarHBondContact O-N 3.3Å; Y28-D32 WeakPolarHBondContact O-CB 3.45Å; Y28-D32 PolarHBondContact O-N 3.38Å; Y28-P135 HydrophobicContact CE2-CB 4.33Å; Y28-P135 HydrophobicContact CE2-CG 4.25Å; Y28-P135 VanDerWaalsContact OH-CB 3.29Å; Y28-P135 WeakPolarHBondContact OH-CB 3.34Å; Y28-P135 VanDerWaalsContact OH-CG 3.28Å; Y28-P135 WeakPolarHBondContact OH-CG 3.12Å; Y28-D372 PolarHBondContact OH-OD2 3.24Å
29W95.3Very high94.1Very high82 Ų8246.8 Ų46.831%0.31124%0.241SC..Hα-helixtrans-65.2-44.8-177.8179.3-91.7000112.2F25 P26 D32 R33F25-W29 HydrophobicContact CE1-CB 4.26Å; F25-W29 HydrophobicContact CE2-CB 4.43Å; F25-W29 HydrophobicContact CE2-CE3 4.22Å; F25-W29 HydrophobicContact CZ-CB 4.09Å; F25-W29 HydrophobicContact CZ-CD2 4.05Å; F25-W29 AromaticContact CZ-CE3 3.73Å; F25-W29 HydrophobicContact CZ-CE3 3.73Å; F25-W29 HydrophobicContact CZ-CG 4.27Å; F25-W29 HydrophobicContact CZ-CZ3 4.5Å; F25-W29 WeakPolarHBondContact O-CB 3.22Å; F25-W29 PolarHBondContact O-N 3.01Å; P26-W29 PolarHBondContact O-N 2.93Å; W29-D32 PolarHBondContact O-N 3.11Å; W29-R33 WeakPolarHBondContact O-CG 3.43Å; W29-R33 PolarHBondContact O-N 2.95Å
30F96Very high93.8Very high41 Ų4142.6 Ų42.618%0.1823%0.226CC..Hα-helixtrans-65.1-39.8177-62.9-46.6000112P26 L34 Y67 L70 L71P26-F30 HydrophobicContact CB-CD2 4.41Å; P26-F30 HydrophobicContact CB-CE2 3.94Å; P26-F30 WeakPolarHBondContact O-CD2 3.1Å; P26-F30 VanDerWaalsContact O-CG 3.29Å; P26-F30 WeakPolarHBondContact O-CG 3.41Å; P26-F30 PolarHBondContact O-N 2.92Å; F30-L34 WeakPolarHBondContact O-CB 3.17Å; F30-L34 PolarHBondContact O-N 2.83Å; F30-Y67 AromaticContact CD1-CD1 3.9Å; F30-Y67 HydrophobicContact CD1-CD1 3.9Å; F30-Y67 HydrophobicContact CD1-CE1 4.26Å; F30-L70 HydrophobicContact CD1-CB 4.14Å; F30-L70 HydrophobicContact CD1-CD1 4.24Å; F30-L70 HydrophobicContact CD2-CB 3.77Å; F30-L70 HydrophobicContact CE1-CB 4.08Å; F30-L70 HydrophobicContact CE1-CD1 3.7Å; F30-L70 HydrophobicContact CE1-CG 4.46Å; F30-L70 HydrophobicContact CE2-CB 3.72Å; F30-L70 HydrophobicContact CG-CB 4.01Å; F30-L70 HydrophobicContact CZ-CB 3.88Å; F30-L70 HydrophobicContact CZ-CD1 3.91Å; F30-L70 HydrophobicContact CZ-CD2 4.45Å; F30-L70 HydrophobicContact CZ-CG 4.3Å; F30-L71 HydrophobicContact CB-CB 4.26Å; F30-L71 HydrophobicContact CB-CD1 4.44Å
31A94.9Very high93.5Very high36 Ų3642.6 Ų42.630%0.29823%0.226SC..Hα-helixtrans-61.8-46.1173.800000111.6C27 Y28 L34 V35 L71C27-A31 WeakPolarHBondContact O-CB 3.42Å; C27-A31 PolarHBondContact O-N 3.45Å; Y28-A31 PolarHBondContact O-N 3.3Å; A31-L34 PolarHBondContact O-N 2.92Å; A31-V35 WeakPolarHBondContact O-CG2 3.43Å; A31-V35 PolarHBondContact O-N 3.3Å; A31-L71 HydrophobicContact CB-CD1 4.03Å
32D94.2Very high93.3Very high5 Ų541 Ų413%0.02722%0.224CC..Hα-helixtrans-59.5-49.1177.1-178.863.5000111.8Y28 W29 L34 V35 A36 D136 S137Y28-D32 WeakPolarHBondContact O-CB 3.45Å; Y28-D32 PolarHBondContact O-N 3.38Å; W29-D32 PolarHBondContact O-N 3.11Å; D32-L34 VanDerWaalsContact C-N 3.35Å; D32-L34 PolarHBondContact O-N 2.91Å; D32-V35 PolarHBondContact O-N 2.85Å; D32-A36 WeakPolarHBondContact O-CB 3.39Å; D32-A36 PolarHBondContact O-N 2.83Å; D32-D136 PolarHBondContact OD1-N 3.13Å; D32-D136 VanDerWaalsContact OD1-N 3.12Å; D32-S137 VanDerWaalsContact OD1-CB 3.29Å; D32-S137 WeakPolarHBondContact OD1-CB 3.22Å; D32-S137 PolarHBondContact OD1-N 3.2Å; D32-S137 PolarHBondContact OD1-OG 3.07Å
33R92.8Very high92.8Very high56 Ų5640.8 Ų40.821%0.21121%0.208CC..Hα-helixtrans-63.1-39.3177.4-68.7-57.4100.91796.3112.7W29 S37 Y67 D136W29-R33 WeakPolarHBondContact O-CG 3.43Å; W29-R33 PolarHBondContact O-N 2.95Å; R33-S37 PolarHBondContact O-N 3.07Å; R33-S37 VanDerWaalsContact O-N 3.16Å; R33-S37 PolarHBondContact O-OG 3.44Å; R33-Y67 HydrophobicContact CB-CD1 4.39Å; R33-Y67 HydrophobicContact CB-CE1 3.97Å; R33-Y67 HydrophobicContact CB-CE2 4.3Å; R33-Y67 HydrophobicContact CG-CE1 4.39Å; R33-D136 IonicContact CZ-OD2 3.25Å; R33-D136 IonicContact NH1-OD2 2.97Å; R33-D136 IonicContact NH2-OD2 3.48Å
34L92.7Very high92.3Very high27 Ų2740.8 Ų40.814%0.14121%0.207CC..Hα-helixtrans-63.5-51.6178.5-178.265.5000110.6F30 A31 D32 S37 F38 T64 L71F30-L34 WeakPolarHBondContact O-CB 3.17Å; F30-L34 PolarHBondContact O-N 2.83Å; A31-L34 PolarHBondContact O-N 2.92Å; D32-L34 VanDerWaalsContact C-N 3.35Å; D32-L34 PolarHBondContact O-N 2.91Å; L34-S37 WeakPolarHBondContact O-CB 3.43Å; L34-S37 PolarHBondContact O-N 2.68Å; L34-F38 HydrophobicContact CD1-CE2 3.85Å; L34-F38 HydrophobicContact CG-CE2 4.3Å; L34-F38 WeakPolarHBondContact O-CD2 3.43Å; L34-T64 HydrophobicContact CD1-CG2 4.09Å; L34-L71 HydrophobicContact CD2-CD2 4.28Å
35V92.1Very high91.9Very high63 Ų6345 Ų4538%0.38222%0.224SC..Hα-helixtrans-64-43.7179177.30000111.1A31 D32 S37 F38 V39A31-V35 WeakPolarHBondContact O-CG2 3.43Å; A31-V35 PolarHBondContact O-N 3.3Å; D32-V35 PolarHBondContact O-N 2.85Å; V35-S37 PolarHBondContact O-N 2.94Å; V35-S37 VanDerWaalsContact O-N 3.17Å; V35-F38 PolarHBondContact O-N 2.9Å; V35-V39 HydrophobicContact CG1-CG2 4.24Å; V35-V39 PolarHBondContact O-N 3.38Å
36A90.4Very high91.3Very high7 Ų747 Ų476%0.05823%0.229CC..Hα-helixtrans-55.5-33.7177.700000112.9D32 F38 V39D32-A36 WeakPolarHBondContact O-CB 3.39Å; D32-A36 PolarHBondContact O-N 2.83Å; A36-F38 PolarHBondContact O-N 3.46Å; A36-V39 PolarHBondContact O-N 2.87Å
37S87.4Confident90.4Very high30 Ų3049.4 Ų49.421%0.2124%0.237CC..THydrogen-bonded Turntrans-65.9-21.6178.5-58.10000113.5R33 L34 V35R33-S37 PolarHBondContact O-N 3.07Å; R33-S37 VanDerWaalsContact O-N 3.16Å; R33-S37 PolarHBondContact O-OG 3.44Å; L34-S37 WeakPolarHBondContact O-CB 3.43Å; L34-S37 PolarHBondContact O-N 2.68Å; V35-S37 PolarHBondContact O-N 2.94Å; V35-S37 VanDerWaalsContact O-N 3.17Å
38F88.5Confident89.4Confident118 Ų11852.6 Ų52.652%0.51825%0.247SC..THydrogen-bonded Turntrans-103.3-7.9-179.9-63.3-73.6000114.1L34 V35 A36 P40 I60 T64L34-F38 HydrophobicContact CD1-CE2 3.85Å; L34-F38 HydrophobicContact CG-CE2 4.3Å; L34-F38 WeakPolarHBondContact O-CD2 3.43Å; V35-F38 PolarHBondContact O-N 2.9Å; A36-F38 PolarHBondContact O-N 3.46Å; F38-P40 WeakPolarHBondContact O-CD 3.1Å; F38-I60 HydrophobicContact CE1-CG2 3.88Å; F38-I60 HydrophobicContact CZ-CG2 4.21Å; F38-T64 HydrophobicContact CE2-CG2 4.48Å; F38-T64 HydrophobicContact CZ-CG2 3.96Å
39V89.6Confident88.2Confident31 Ų3153.7 Ų53.719%0.18827%0.268CS..SBendtrans-115.786.2-178.6-170.60000109.5V35 A36 R140 F141V35-V39 HydrophobicContact CG1-CG2 4.24Å; V35-V39 PolarHBondContact O-N 3.38Å; A36-V39 PolarHBondContact O-N 2.87Å; V39-R140 HydrophobicContact CB-CB 4.17Å; V39-R140 HydrophobicContact CG1-CB 3.79Å; V39-R140 WeakPolarHBondContact O-CD 3.18Å; V39-R140 PolarHBondContact O-NH1 2.89Å; V39-F141 HydrophobicContact CG1-CE1 4.42Å; V39-F141 HydrophobicContact CG1-CZ 4.48Å; V39-F141 HydrophobicContact CG2-CZ 4.14Å
40P89.3Confident86.9Confident30 Ų3055.8 Ų55.820%0.19529%0.285CS..  trans-82.5141-178.332.1-35.4000113.2F38 E44 K45 R48F38-P40 WeakPolarHBondContact O-CD 3.1Å; P40-E44 WeakPolarHBondContact CA-OE2 3.42Å; P40-K45 HydrophobicContact CB-CG 4.25Å; P40-K45 HydrophobicContact CG-CG 4.28Å; P40-K45 WeakPolarHBondContact O-CE 3.18Å; P40-R48 VanDerWaalsContact CB-NH2 3.32Å
41T91.3Very high85.2Confident0 Ų057.7 Ų57.70%030%0.298CS..  trans-74.2162.7171.361.50000111.8Y43 E44 K45 R140 N143 F145T41-Y43 PolarHBondContact O-N 3.39Å; T41-E44 PolarHBondContact N-OE2 3.46Å; T41-E44 PolarHBondContact O-N 2.87Å; T41-E44 WeakPolarHBondContact OG1-CG 3.46Å; T41-E44 PolarHBondContact OG1-N 2.92Å; T41-E44 PolarHBondContact OG1-OE2 3.14Å; T41-E44 VanDerWaalsContact OG1-OE2 3.1Å; T41-K45 WeakPolarHBondContact O-CG 3.23Å; T41-K45 PolarHBondContact O-N 2.95Å; T41-R140 HydrophobicContact CG2-CG 4.14Å; T41-N143 WeakPolarHBondContact CA-OD1 3.26Å; T41-N143 VanDerWaalsContact CB-OD1 3.3Å; T41-N143 WeakPolarHBondContact CB-OD1 3.39Å; T41-F145 HydrophobicContact CG2-CB 4.01Å; T41-F145 HydrophobicContact CG2-CD1 3.85Å; T41-F145 HydrophobicContact CG2-CG 4.28Å
42T90.1Very high83.6Confident33 Ų3361.4 Ų61.420%0.20232%0.319CS..Hα-helixtrans-63.8-29.9175.1630000111.8K45 R46 N143 E560 Y563T42-K45 PolarHBondContact O-N 2.9Å; T42-R46 PolarHBondContact O-N 3.05Å; T42-N143 PolarHBondContact N-OD1 2.94Å; T42-N143 PolarHBondContact OG1-ND2 3Å; T42-E560 PolarHBondContact OG1-O 2.81Å; T42-Y563 WeakPolarHBondContact OG1-CD2 3.49Å
43Y87.1Confident82Confident44 Ų4465 Ų6517%0.17334%0.343CS..Hα-helixtrans-58.8-54.6170.1-179.7-101.7000112T41 K45 R46 Q47 F145 I244 Y563T41-Y43 PolarHBondContact O-N 3.39Å; Y43-K45 VanDerWaalsContact C-N 3.29Å; Y43-K45 PolarHBondContact O-N 2.95Å; Y43-R46 PolarHBondContact O-N 3.04Å; Y43-Q47 HydrophobicContact CE1-CG 4.31Å; Y43-Q47 VanDerWaalsContact CE1-NE2 3.33Å; Y43-Q47 PolarHBondContact O-N 3.36Å; Y43-Q47 PolarHBondContact OH-NE2 3.14Å; Y43-F145 AromaticContact CD1-CE1 3.89Å; Y43-F145 HydrophobicContact CD1-CE1 3.89Å; Y43-F145 AromaticContact CD1-CZ 3.68Å; Y43-F145 HydrophobicContact CD1-CZ 3.68Å; Y43-F145 HydrophobicContact CE1-CZ 4.02Å; Y43-F145 HydrophobicContact CG-CE1 4.25Å; Y43-F145 HydrophobicContact CG-CZ 4.42Å; Y43-I244 HydrophobicContact CE2-CB 4.47Å; Y43-I244 HydrophobicContact CE2-CD1 3.55Å; Y43-I244 HydrophobicContact CE2-CG1 3.82Å; Y43-I244 HydrophobicContact CE2-CG2 3.9Å; Y43-I244 WeakPolarHBondContact OH-CG2 3.39Å; Y43-Y563 HydrophobicContact CD2-CG 4.44Å
44E87Confident81Confident34 Ų3472 Ų7216%0.15937%0.371CS..Hα-helixtrans-64.6-34.3178.7-68.1162.8149.600111.5P40 T41 R48 R140P40-E44 WeakPolarHBondContact CA-OE2 3.42Å; T41-E44 PolarHBondContact N-OE2 3.46Å; T41-E44 PolarHBondContact O-N 2.87Å; T41-E44 WeakPolarHBondContact OG1-CG 3.46Å; T41-E44 PolarHBondContact OG1-N 2.92Å; T41-E44 PolarHBondContact OG1-OE2 3.14Å; T41-E44 VanDerWaalsContact OG1-OE2 3.1Å; E44-R48 WeakPolarHBondContact O-CD 3.46Å; E44-R48 WeakPolarHBondContact O-CG 3.33Å; E44-R48 PolarHBondContact O-N 2.93Å; E44-R48 VanDerWaalsContact O-N 3.14Å; E44-R140 VanDerWaalsContact CD-NH1 3.3Å; E44-R140 IonicContact OE1-CZ 3.01Å; E44-R140 IonicContact OE1-NH1 3.77Å; E44-R140 PolarHBondContact OE1-NH1 2.97Å; E44-R140 IonicContact OE1-NH2 2.72Å; E44-R140 PolarHBondContact OE1-NH2 3.24Å; E44-R140 IonicContact OE2-CZ 3.53Å; E44-R140 IonicContact OE2-NH1 3.85Å; E44-R140 PolarHBondContact OE2-NH1 2.63Å; E44-R140 IonicContact OE2-NH2 3.78Å
45K86.4Confident80.2Confident115 Ų11577.1 Ų77.150%0.539%0.393SS..Hα-helixtrans-64.7-40.1174-71.8174-172.11720112.3P40 T41 T42 Y43 R48 A49P40-K45 HydrophobicContact CB-CG 4.25Å; P40-K45 HydrophobicContact CG-CG 4.28Å; P40-K45 WeakPolarHBondContact O-CE 3.18Å; T41-K45 WeakPolarHBondContact O-CG 3.23Å; T41-K45 PolarHBondContact O-N 2.95Å; T42-K45 PolarHBondContact O-N 2.9Å; Y43-K45 VanDerWaalsContact C-N 3.29Å; Y43-K45 PolarHBondContact O-N 2.95Å; K45-R48 PolarHBondContact O-N 3.48Å; K45-A49 PolarHBondContact O-N 2.98Å
46R82.9Confident79.3Confident110 Ų11077.9 Ų77.942%0.41539%0.392SS..Hα-helixtrans-65.3-48.9176.7-175.3178.2-70.4159.84110.7T42 Y43 R48 A49 D50 Y563 D564T42-R46 PolarHBondContact O-N 3.05Å; Y43-R46 PolarHBondContact O-N 3.04Å; R46-R48 PolarHBondContact O-N 3.16Å; R46-A49 WeakPolarHBondContact O-CB 3.16Å; R46-A49 PolarHBondContact O-N 2.7Å; R46-D50 PolarHBondContact O-N 3.33Å; R46-Y563 PolarHBondContact NH1-O 3.02Å; R46-D564 IonicContact CZ-OD1 3.65Å; R46-D564 IonicContact NH1-OD1 3.78Å; R46-D564 IonicContact NH2-OD1 2.66Å; R46-D564 PolarHBondContact NH2-OD1 2.99Å
47Q79Confident78.8Confident97 Ų9779.7 Ų79.745%0.45341%0.407SS..Hα-helixtrans-55.8-36.3176.4-73.1-170.2-27.900113.4Y43 D50 D51Y43-Q47 HydrophobicContact CE1-CG 4.31Å; Y43-Q47 VanDerWaalsContact CE1-NE2 3.33Å; Y43-Q47 PolarHBondContact O-N 3.36Å; Y43-Q47 PolarHBondContact OH-NE2 3.14Å; Q47-D50 PolarHBondContact O-N 3.39Å; Q47-D51 PolarHBondContact O-N 2.88Å
48R75.8Confident78.6Confident85 Ų8582.6 Ų82.632%0.32142%0.419SS..Hα-helixtrans-70-29.5175.9-71.1167.3-169.3163.8-2114.2P40 E44 K45 R46 D50 D51 H56P40-R48 VanDerWaalsContact CB-NH2 3.32Å; E44-R48 WeakPolarHBondContact O-CD 3.46Å; E44-R48 WeakPolarHBondContact O-CG 3.33Å; E44-R48 PolarHBondContact O-N 2.93Å; E44-R48 VanDerWaalsContact O-N 3.14Å; K45-R48 PolarHBondContact O-N 3.48Å; R46-R48 PolarHBondContact O-N 3.16Å; R48-D50 PolarHBondContact O-N 3.1Å; R48-D51 VanDerWaalsContact O-O 3.06Å; R48-H56 PolarHBondContact NH2-CD2 3.15Å; R48-H56 PolarHBondContact NH2-NE2 3.18Å
49A69.9Low78.4Confident84 Ų8478.9 Ų78.969%0.69441%0.408SS*.Hα-helixtrans-67.6-29.6174.800000110.5K45 R46K45-A49 PolarHBondContact O-N 2.98Å; R46-A49 WeakPolarHBondContact O-CB 3.16Å; R46-A49 PolarHBondContact O-N 2.7Å
50D68.4Low78.2Confident125 Ų12579.1 Ų79.167%0.66841%0.408SS*.Hα-helixtrans-88.7-18.4-179.7-56.4-31.5000113R46 Q47 R48 P52R46-D50 PolarHBondContact O-N 3.33Å; Q47-D50 PolarHBondContact O-N 3.39Å; R48-D50 PolarHBondContact O-N 3.1Å; D50-P52 WeakPolarHBondContact O-CD 3.26Å
51D60.2Low78.2Confident82 Ų8283.4 Ų83.444%0.43943%0.428SS..  trans-110.499.6174.2-171.31.4000112.1Q47 R48 C53Q47-D51 PolarHBondContact O-N 2.88Å; R48-D51 VanDerWaalsContact O-O 3.06Å; D51-C53 PolarHBondContact O-N 3.48Å; D51-C53 VanDerWaalsContact O-N 3.12Å; D51-C53 VanDerWaalsContact OD1-CB 3.31Å; D51-C53 WeakPolarHBondContact OD1-CB 3.4Å; D51-C53 PolarHBondContact OD1-N 3.48Å; D51-C53 VanDerWaalsContact OD1-N 3.16Å; D51-C53 PolarHBondContact OD1-SG 3.01Å; D51-C53 VanDerWaalsContact OD1-SG 3.42Å
52P60.4Low78.2Confident114 Ų11487.8 Ų87.874%0.7445%0.45SS*.  trans-72.60.1-178.229.3-34.1000113.9D50D50-P52 WeakPolarHBondContact O-CD 3.26Å
53C60.7Low78.1Confident80 Ų8088.3 Ų88.354%0.54145%0.453SS..  trans-80.2125.6-178.5-600000110.4D51 F55D51-C53 PolarHBondContact O-N 3.48Å; D51-C53 VanDerWaalsContact O-N 3.12Å; D51-C53 VanDerWaalsContact OD1-CB 3.31Å; D51-C53 WeakPolarHBondContact OD1-CB 3.4Å; D51-C53 PolarHBondContact OD1-N 3.48Å; D51-C53 VanDerWaalsContact OD1-N 3.16Å; D51-C53 PolarHBondContact OD1-SG 3.01Å; D51-C53 VanDerWaalsContact OD1-SG 3.42Å; C53-F55 HydrophobicContact CB-CB 4.2Å; C53-F55 PolarHBondContact O-N 3.39Å
54Y71.1Confident78.4Confident202 Ų20287.9 Ų87.979%0.79246%0.455SS*.THydrogen-bonded Turntrans-60.514.3169.8-65.1-85.8000114.2H56 A57 L58Y54-H56 PolarHBondContact O-N 2.85Å; Y54-A57 PolarHBondContact O-N 2.82Å; Y54-L58 WeakPolarHBondContact O-CB 3.37Å; Y54-L58 PolarHBondContact O-N 3.16Å
55F76.8Confident78.8Confident136 Ų13689.8 Ų89.860%0.59647%0.47SS*.Hα-helixtrans-56-45.9-178.7-176.2-102.3000111.8C53 A57 L58 C59C53-F55 HydrophobicContact CB-CB 4.2Å; C53-F55 PolarHBondContact O-N 3.39Å; F55-A57 PolarHBondContact O-N 2.9Å; F55-L58 WeakPolarHBondContact O-CB 3.25Å; F55-L58 PolarHBondContact O-N 3.22Å; F55-C59 PolarHBondContact O-N 3.04Å; F55-C59 PolarHBondContact O-SG 3.48Å
56H73.8Confident79.2Confident78 Ų7888.6 Ų88.636%0.36147%0.469SS..Hα-helixtrans-67.1-39.5178.1-171.775.9000112.7R48 Y54 L58 C59 I60R48-H56 PolarHBondContact NH2-CD2 3.15Å; R48-H56 PolarHBondContact NH2-NE2 3.18Å; Y54-H56 PolarHBondContact O-N 2.85Å; H56-L58 VanDerWaalsContact C-N 3.3Å; H56-L58 PolarHBondContact O-N 2.68Å; H56-C59 WeakPolarHBondContact O-CB 3.32Å; H56-C59 PolarHBondContact O-N 3.07Å; H56-I60 WeakPolarHBondContact O-CG1 3.47Å; H56-I60 PolarHBondContact O-N 3.19Å
57A80.1Confident79.8Confident45 Ų4586.3 Ų86.337%0.37246%0.46SS..Hα-helixtrans-62.8-40.4174.500000111Y54 F55 I60 I61Y54-A57 PolarHBondContact O-N 2.82Å; F55-A57 PolarHBondContact O-N 2.9Å; A57-I60 PolarHBondContact O-N 2.95Å; A57-I61 WeakPolarHBondContact O-CD1 3.49Å; A57-I61 VanDerWaalsContact O-CG1 3.24Å; A57-I61 WeakPolarHBondContact O-CG1 3.48Å; A57-I61 PolarHBondContact O-N 2.93Å
58L83.3Confident80.5Confident91 Ų9185.9 Ų85.948%0.47646%0.461SS..Hα-helixtrans-62.8-44.3173-177.667.1000111.7Y54 F55 H56 I60 I61 I62Y54-L58 WeakPolarHBondContact O-CB 3.37Å; Y54-L58 PolarHBondContact O-N 3.16Å; F55-L58 WeakPolarHBondContact O-CB 3.25Å; F55-L58 PolarHBondContact O-N 3.22Å; H56-L58 VanDerWaalsContact C-N 3.3Å; H56-L58 PolarHBondContact O-N 2.68Å; L58-I60 VanDerWaalsContact C-N 3.34Å; L58-I60 PolarHBondContact O-N 3.31Å; L58-I61 PolarHBondContact O-N 3.29Å; L58-I62 HydrophobicContact CD1-CD1 3.94Å; L58-I62 HydrophobicContact CD1-CG1 4.36Å; L58-I62 HydrophobicContact CG-CD1 3.86Å; L58-I62 WeakPolarHBondContact O-CG1 3.43Å; L58-I62 PolarHBondContact O-N 3.29Å
59C83.5Confident81.5Confident41 Ų4184.8 Ų84.828%0.27747%0.47SS..Hα-helixtrans-57.8-45.6173.7-70.20000111.2F55 H56 I62 T63F55-C59 PolarHBondContact O-N 3.04Å; F55-C59 PolarHBondContact O-SG 3.48Å; H56-C59 WeakPolarHBondContact O-CB 3.32Å; H56-C59 PolarHBondContact O-N 3.07Å; C59-I62 PolarHBondContact O-N 3.39Å; C59-T63 VanDerWaalsContact O-CB 3.24Å; C59-T63 WeakPolarHBondContact O-CB 3.12Å; C59-T63 WeakPolarHBondContact O-CG2 3.26Å; C59-T63 PolarHBondContact O-N 3.45Å; C59-T63 PolarHBondContact O-OG1 3.37Å
60I85.8Confident82.8Confident36 Ų3684.1 Ų84.119%0.18545%0.454CS..Hα-helixtrans-61.8-46.9176.2-68.1169.6000110.5F38 H56 A57 L58 I62 T63 T64F38-I60 HydrophobicContact CE1-CG2 3.88Å; F38-I60 HydrophobicContact CZ-CG2 4.21Å; H56-I60 WeakPolarHBondContact O-CG1 3.47Å; H56-I60 PolarHBondContact O-N 3.19Å; A57-I60 PolarHBondContact O-N 2.95Å; L58-I60 VanDerWaalsContact C-N 3.34Å; L58-I60 PolarHBondContact O-N 3.31Å; I60-I62 VanDerWaalsContact C-N 3.29Å; I60-I62 PolarHBondContact O-N 2.94Å; I60-T63 PolarHBondContact O-N 3.38Å; I60-T64 WeakPolarHBondContact O-CB 3.49Å; I60-T64 PolarHBondContact O-N 2.85Å; I60-T64 PolarHBondContact O-OG1 3.31Å
61I89.1Confident84.1Confident120 Ų12079.6 Ų79.662%0.61543%0.43SS*.Hα-helixtrans-60.2-38.4-179.7-70.5164.6000111.7A57 L58 P65A57-I61 WeakPolarHBondContact O-CD1 3.49Å; A57-I61 VanDerWaalsContact O-CG1 3.24Å; A57-I61 WeakPolarHBondContact O-CG1 3.48Å; A57-I61 PolarHBondContact O-N 2.93Å; L58-I61 PolarHBondContact O-N 3.29Å; I61-P65 WeakPolarHBondContact O-CD 3.23Å; I61-P65 WeakPolarHBondContact O-CG 3.39Å
62I89.8Confident85.9Confident92 Ų9279.8 Ų79.847%0.47243%0.434SS..Hα-helixtrans-79.1-44.9179.6-65.7171000111.5L58 C59 I60 P65 I66L58-I62 HydrophobicContact CD1-CD1 3.94Å; L58-I62 HydrophobicContact CD1-CG1 4.36Å; L58-I62 HydrophobicContact CG-CD1 3.86Å; L58-I62 WeakPolarHBondContact O-CG1 3.43Å; L58-I62 PolarHBondContact O-N 3.29Å; C59-I62 PolarHBondContact O-N 3.39Å; I60-I62 VanDerWaalsContact C-N 3.29Å; I60-I62 PolarHBondContact O-N 2.94Å; I62-P65 VanDerWaalsContact O-CD 3.3Å; I62-P65 WeakPolarHBondContact O-CD 3.31Å; I62-P65 VanDerWaalsContact O-CG 3.3Å; I62-P65 WeakPolarHBondContact O-CG 3.29Å; I62-I66 HydrophobicContact CG2-CD1 4.13Å; I62-I66 WeakPolarHBondContact O-CD1 3.2Å; I62-I66 WeakPolarHBondContact O-CG1 3.33Å
63T90.1Very high87.7Confident43 Ų4377.3 Ų77.326%0.26442%0.423SS..Hα-helixtrans-76.2-31.8-174.157.40000113.1C59 I60 I66 Y67C59-T63 VanDerWaalsContact O-CB 3.24Å; C59-T63 WeakPolarHBondContact O-CB 3.12Å; C59-T63 WeakPolarHBondContact O-CG2 3.26Å; C59-T63 PolarHBondContact O-N 3.45Å; C59-T63 PolarHBondContact O-OG1 3.37Å; I60-T63 PolarHBondContact O-N 3.38Å; T63-I66 PolarHBondContact O-N 2.73Å; T63-Y67 VanDerWaalsContact O-CD2 3.25Å; T63-Y67 WeakPolarHBondContact O-CD2 3.38Å; T63-Y67 PolarHBondContact O-N 2.97Å
64T93.4Very high89.4Confident35 Ų3574 Ų7422%0.21540%0.401CS..Hα-helixtrans-55.4-54.8178.5-63.30000113.1L34 F38 I60 I66 Y67 L68L34-T64 HydrophobicContact CD1-CG2 4.09Å; F38-T64 HydrophobicContact CE2-CG2 4.48Å; F38-T64 HydrophobicContact CZ-CG2 3.96Å; I60-T64 WeakPolarHBondContact O-CB 3.49Å; I60-T64 PolarHBondContact O-N 2.85Å; I60-T64 PolarHBondContact O-OG1 3.31Å; T64-I66 VanDerWaalsContact C-N 3.27Å; T64-I66 PolarHBondContact O-N 2.87Å; T64-Y67 PolarHBondContact O-N 3.09Å; T64-L68 VanDerWaalsContact O-CB 3.32Å; T64-L68 WeakPolarHBondContact O-CB 3.39Å; T64-L68 PolarHBondContact O-N 3.29Å
65P94.9Very high90.7Very high74 Ų7468.7 Ų68.748%0.48139%0.386SS..Hα-helixtrans-64.3-32.5179.525-34.4000112.3I61 I62 A69I61-P65 WeakPolarHBondContact O-CD 3.23Å; I61-P65 WeakPolarHBondContact O-CG 3.39Å; I62-P65 VanDerWaalsContact O-CD 3.3Å; I62-P65 WeakPolarHBondContact O-CD 3.31Å; I62-P65 VanDerWaalsContact O-CG 3.3Å; I62-P65 WeakPolarHBondContact O-CG 3.29Å; P65-A69 WeakPolarHBondContact O-CB 3.34Å; P65-A69 PolarHBondContact O-N 2.85Å
66I94.3Very high91.7Very high91 Ų9165.8 Ų65.847%0.46738%0.381SS..Hα-helixtrans-65-52.8175.9-62.8170.6000110.1I62 T63 T64 L68 A69 L70I62-I66 HydrophobicContact CG2-CD1 4.13Å; I62-I66 WeakPolarHBondContact O-CD1 3.2Å; I62-I66 WeakPolarHBondContact O-CG1 3.33Å; T63-I66 PolarHBondContact O-N 2.73Å; T64-I66 VanDerWaalsContact C-N 3.27Å; T64-I66 PolarHBondContact O-N 2.87Å; I66-L68 VanDerWaalsContact C-N 3.3Å; I66-L68 PolarHBondContact O-N 3.22Å; I66-A69 PolarHBondContact O-N 3.32Å; I66-L70 HydrophobicContact CG2-CD1 3.9Å; I66-L70 HydrophobicContact CG2-CG 4.49Å; I66-L70 WeakPolarHBondContact O-CB 3.38Å; I66-L70 VanDerWaalsContact O-CG 3.31Å; I66-L70 WeakPolarHBondContact O-CG 3.37Å; I66-L70 PolarHBondContact O-N 2.72Å
67Y94.5Very high92.8Very high61 Ų6167.8 Ų67.824%0.23939%0.388CS..Hα-helixtrans-62.1-37.9177.9-75.3-51.4000112.3F30 R33 T63 T64 L70 L71F30-Y67 AromaticContact CD1-CD1 3.9Å; F30-Y67 HydrophobicContact CD1-CD1 3.9Å; F30-Y67 HydrophobicContact CD1-CE1 4.26Å; R33-Y67 HydrophobicContact CB-CD1 4.39Å; R33-Y67 HydrophobicContact CB-CE1 3.97Å; R33-Y67 HydrophobicContact CB-CE2 4.3Å; R33-Y67 HydrophobicContact CG-CE1 4.39Å; T63-Y67 VanDerWaalsContact O-CD2 3.25Å; T63-Y67 WeakPolarHBondContact O-CD2 3.38Å; T63-Y67 PolarHBondContact O-N 2.97Å; T64-Y67 PolarHBondContact O-N 3.09Å; Y67-L70 PolarHBondContact O-N 3.34Å; Y67-L71 WeakPolarHBondContact O-CB 3.4Å; Y67-L71 PolarHBondContact O-N 3.05Å
68L95.6Very high93.6Very high88 Ų8866.2 Ų66.246%0.46138%0.376SS..Hα-helixtrans-64.8-44.2176.3-174.663.7000111.6T64 I66 L71 V72T64-L68 VanDerWaalsContact O-CB 3.32Å; T64-L68 WeakPolarHBondContact O-CB 3.39Å; T64-L68 PolarHBondContact O-N 3.29Å; I66-L68 VanDerWaalsContact C-N 3.3Å; I66-L68 PolarHBondContact O-N 3.22Å; L68-L71 PolarHBondContact O-N 3.11Å; L68-V72 WeakPolarHBondContact O-CG2 3.38Å; L68-V72 PolarHBondContact O-N 3.23Å
69A96.4Very high94.3Very high62 Ų6267.1 Ų67.151%0.51238%0.38SS..Hα-helixtrans-62.7-44.6176.600000111.7P65 I66 V72 A73P65-A69 WeakPolarHBondContact O-CB 3.34Å; P65-A69 PolarHBondContact O-N 2.85Å; I66-A69 PolarHBondContact O-N 3.32Å; A69-V72 PolarHBondContact O-N 3.27Å; A69-A73 WeakPolarHBondContact O-CB 3.08Å; A69-A73 PolarHBondContact O-N 3.17Å
70L96.7Very high94.9Very high70 Ų7069.4 Ų69.437%0.36639%0.389SS..Hα-helixtrans-65.7-37.5176.8-68.5173.1000112.4F30 I66 Y67 A73 S74F30-L70 HydrophobicContact CD1-CB 4.14Å; F30-L70 HydrophobicContact CD1-CD1 4.24Å; F30-L70 HydrophobicContact CD2-CB 3.77Å; F30-L70 HydrophobicContact CE1-CB 4.08Å; F30-L70 HydrophobicContact CE1-CD1 3.7Å; F30-L70 HydrophobicContact CE1-CG 4.46Å; F30-L70 HydrophobicContact CE2-CB 3.72Å; F30-L70 HydrophobicContact CG-CB 4.01Å; F30-L70 HydrophobicContact CZ-CB 3.88Å; F30-L70 HydrophobicContact CZ-CD1 3.91Å; F30-L70 HydrophobicContact CZ-CD2 4.45Å; F30-L70 HydrophobicContact CZ-CG 4.3Å; I66-L70 HydrophobicContact CG2-CD1 3.9Å; I66-L70 HydrophobicContact CG2-CG 4.49Å; I66-L70 WeakPolarHBondContact O-CB 3.38Å; I66-L70 VanDerWaalsContact O-CG 3.31Å; I66-L70 WeakPolarHBondContact O-CG 3.37Å; I66-L70 PolarHBondContact O-N 2.72Å; Y67-L70 PolarHBondContact O-N 3.34Å; L70-A73 PolarHBondContact O-N 2.82Å; L70-S74 WeakPolarHBondContact O-CB 3.49Å; L70-S74 PolarHBondContact O-N 3.23Å; L70-S74 PolarHBondContact O-OG 2.79Å
71L96.4Very high95.4Very high30 Ų3067.7 Ų67.716%0.15738%0.38CS..Hα-helixtrans-61.2-51.8173.5179.963.1000110.4C27 F30 A31 L34 Y67 L68 A73 S74 L75C27-L71 WeakPolarHBondContact O-CD1 3.5Å; C27-L71 VanDerWaalsContact SG-CD1 3.56Å; F30-L71 HydrophobicContact CB-CB 4.26Å; F30-L71 HydrophobicContact CB-CD1 4.44Å; A31-L71 HydrophobicContact CB-CD1 4.03Å; L34-L71 HydrophobicContact CD2-CD2 4.28Å; Y67-L71 WeakPolarHBondContact O-CB 3.4Å; Y67-L71 PolarHBondContact O-N 3.05Å; L68-L71 PolarHBondContact O-N 3.11Å; L71-A73 VanDerWaalsContact C-N 3.31Å; L71-A73 PolarHBondContact O-N 3.42Å; L71-S74 PolarHBondContact O-N 2.8Å; L71-S74 VanDerWaalsContact O-N 3.12Å; L71-S74 PolarHBondContact O-OG 3.15Å; L71-L75 WeakPolarHBondContact O-CG 2.93Å; L71-L75 PolarHBondContact O-N 2.91Å; L71-L75 VanDerWaalsContact O-N 3.09Å
72V97.3Very high95.6Very high87 Ų8765.5 Ų65.553%0.52737%0.366SS..Hα-helixtrans-60.7-41.4178.7173.20000111.6L68 A69 S74 L75L68-V72 WeakPolarHBondContact O-CG2 3.38Å; L68-V72 PolarHBondContact O-N 3.23Å; A69-V72 PolarHBondContact O-N 3.27Å; V72-S74 VanDerWaalsContact C-N 3.29Å; V72-S74 PolarHBondContact O-N 2.92Å; V72-L75 PolarHBondContact O-N 2.93Å
73A97.4Very high95.9Very high62 Ų6266.6 Ų66.651%0.51237%0.372SS..Hα-helixtrans-65.5-30.4177.600000113.2A69 L70 L71A69-A73 WeakPolarHBondContact O-CB 3.08Å; A69-A73 PolarHBondContact O-N 3.17Å; L70-A73 PolarHBondContact O-N 2.82Å; L71-A73 VanDerWaalsContact C-N 3.31Å; L71-A73 PolarHBondContact O-N 3.42Å
74S97.6Very high96Very high10 Ų1067.5 Ų67.57%0.0738%0.375CS..Hα-helixtrans-88.2-17.1-178.956.90000114.4C27 L70 L71 V72 F77 A78C27-S74 VanDerWaalsContact CA-OG 3.29Å; C27-S74 WeakPolarHBondContact CA-OG 3.4Å; L70-S74 WeakPolarHBondContact O-CB 3.49Å; L70-S74 PolarHBondContact O-N 3.23Å; L70-S74 PolarHBondContact O-OG 2.79Å; L71-S74 PolarHBondContact O-N 2.8Å; L71-S74 VanDerWaalsContact O-N 3.12Å; L71-S74 PolarHBondContact O-OG 3.15Å; V72-S74 VanDerWaalsContact C-N 3.29Å; V72-S74 PolarHBondContact O-N 2.92Å; S74-F77 PolarHBondContact O-N 2.8Å; S74-A78 PolarHBondContact O-N 2.73Å
75L97.4Very high96Very high91 Ų9166.5 Ų66.548%0.47637%0.368SS..Hα-helixtrans-53.4-44.9179.9-79.7171.7000114.6L71 V72 F77 A78 L79L71-L75 WeakPolarHBondContact O-CG 2.93Å; L71-L75 PolarHBondContact O-N 2.91Å; L71-L75 VanDerWaalsContact O-N 3.09Å; V72-L75 PolarHBondContact O-N 2.93Å; L75-F77 VanDerWaalsContact C-N 3.33Å; L75-F77 PolarHBondContact O-N 2.81Å; L75-A78 PolarHBondContact O-N 3.36Å; L75-L79 PolarHBondContact O-N 3.4Å
76P97.7Very high95.8Very high75 Ų7564.7 Ų64.749%0.48736%0.356SS..Hα-helixtrans-63-39.6-180-22.734.4000112.7L79 I80P76-L79 PolarHBondContact O-N 3.45Å; P76-I80 WeakPolarHBondContact O-CG1 3.26Å; P76-I80 PolarHBondContact O-N 2.85Å
77F97.6Very high95.6Very high119 Ų11964 Ų6452%0.52236%0.358SS..Hα-helixtrans-67.6-43.5176.5-59-78.1000110.8L23 S74 L75 L79 I80 G81L23-F77 WeakPolarHBondContact CB-O 3.42Å; L23-F77 HydrophobicContact CD2-CB 4.37Å; L23-F77 HydrophobicContact CD2-CD1 4.43Å; S74-F77 PolarHBondContact O-N 2.8Å; L75-F77 VanDerWaalsContact C-N 3.33Å; L75-F77 PolarHBondContact O-N 2.81Å; F77-L79 VanDerWaalsContact C-N 3.28Å; F77-L79 PolarHBondContact O-N 2.97Å; F77-I80 PolarHBondContact O-N 2.85Å; F77-G81 PolarHBondContact O-N 2.56Å
78A97.2Very high95.4Very high13 Ų1361.6 Ų61.611%0.10735%0.349CS..Hα-helixtrans-61.9-36.3176.700000112.4L23 C27 S74 L75 G81 F82L23-A78 PolarHBondContact O-N 2.99Å; C27-A78 HydrophobicContact CB-CB 3.46Å; C27-A78 VanDerWaalsContact CB-CB 3.46Å; S74-A78 PolarHBondContact O-N 2.73Å; L75-A78 PolarHBondContact O-N 3.36Å; A78-G81 PolarHBondContact O-N 3.28Å; A78-F82 VanDerWaalsContact O-CB 3.27Å; A78-F82 WeakPolarHBondContact O-CB 3.3Å; A78-F82 PolarHBondContact O-N 2.81Å
79L96.8Very high95.1Very high109 Ų10957.6 Ų57.657%0.57133%0.328SS*.Hα-helixtrans-62.7-47.6173.818062.6000111.6L75 P76 F77 G81 F82 L83L75-L79 PolarHBondContact O-N 3.4Å; P76-L79 PolarHBondContact O-N 3.45Å; F77-L79 VanDerWaalsContact C-N 3.28Å; F77-L79 PolarHBondContact O-N 2.97Å; L79-G81 VanDerWaalsContact C-N 3.35Å; L79-F82 PolarHBondContact O-N 2.88Å; L79-L83 HydrophobicContact CG-CD1 4.47Å; L79-L83 WeakPolarHBondContact O-CG 3.4Å; L79-L83 PolarHBondContact O-N 2.96Å
80I97.3Very high94.6Very high90 Ų9058.1 Ų58.146%0.46233%0.328SS..Hα-helixtrans-60.9-47.2176-64.9166.8000110.1L23 P76 F77 F82 L83 L84L23-I80 HydrophobicContact CD1-CB 4.49Å; L23-I80 HydrophobicContact CD1-CG2 4.03Å; P76-I80 WeakPolarHBondContact O-CG1 3.26Å; P76-I80 PolarHBondContact O-N 2.85Å; F77-I80 PolarHBondContact O-N 2.85Å; I80-F82 VanDerWaalsContact C-N 3.3Å; I80-F82 PolarHBondContact O-N 2.91Å; I80-L83 PolarHBondContact O-N 2.94Å; I80-L84 HydrophobicContact CG2-CD1 4.31Å; I80-L84 WeakPolarHBondContact O-CG 3.33Å; I80-L84 PolarHBondContact O-N 2.9Å; I80-L84 VanDerWaalsContact O-N 3.1Å
81G96.8Very high94.3Very high0 Ų056.7 Ų56.70%033%0.327CS..Hα-helixtrans-57.1-42.7176.100000112.2F77 A78 L79 L84 W85F77-G81 PolarHBondContact O-N 2.56Å; A78-G81 PolarHBondContact O-N 3.28Å; L79-G81 VanDerWaalsContact C-N 3.35Å; G81-L84 PolarHBondContact O-N 2.98Å; G81-W85 WeakPolarHBondContact O-CB 3.35Å; G81-W85 PolarHBondContact O-N 2.87Å
82F93.6Very high94.1Very high74 Ų7456.2 Ų56.233%0.32532%0.323SS..Hα-helixtrans-65.5-41.8178-179.4-97.7000112.6A78 L79 I80 L84 W85 S86 F405 F407A78-F82 VanDerWaalsContact O-CB 3.27Å; A78-F82 WeakPolarHBondContact O-CB 3.3Å; A78-F82 PolarHBondContact O-N 2.81Å; L79-F82 PolarHBondContact O-N 2.88Å; I80-F82 VanDerWaalsContact C-N 3.3Å; I80-F82 PolarHBondContact O-N 2.91Å; F82-L84 PolarHBondContact O-N 2.77Å; F82-W85 AromaticContact CD2-CE3 3.92Å; F82-W85 HydrophobicContact CD2-CE3 3.92Å; F82-W85 HydrophobicContact CD2-CZ3 4.24Å; F82-W85 HydrophobicContact CE2-CE3 4.01Å; F82-W85 AromaticContact CE2-CZ3 3.92Å; F82-W85 HydrophobicContact CE2-CZ3 3.92Å; F82-W85 PolarHBondContact O-N 2.96Å; F82-S86 VanDerWaalsContact O-CB 3.3Å; F82-S86 WeakPolarHBondContact O-CB 3.37Å; F82-S86 PolarHBondContact O-N 2.83Å; F82-F405 HydrophobicContact CE2-CE1 4.26Å; F82-F405 AromaticContact CE2-CZ 3.92Å; F82-F405 HydrophobicContact CE2-CZ 3.92Å; F82-F405 HydrophobicContact CZ-CE1 4.28Å; F82-F405 AromaticContact CZ-CZ 3.85Å; F82-F405 HydrophobicContact CZ-CZ 3.85Å; F82-F407 HydrophobicContact CE2-CE1 4.31Å
83L94.3Very high93.9Very high114 Ų11455.2 Ų55.260%0.59731%0.309SS*.Hα-helixtrans-63.1-32176.5-69.9173.4000112.3L79 I80 P87L79-L83 HydrophobicContact CG-CD1 4.47Å; L79-L83 WeakPolarHBondContact O-CG 3.4Å; L79-L83 PolarHBondContact O-N 2.96Å; I80-L83 PolarHBondContact O-N 2.94Å; L83-P87 WeakPolarHBondContact O-CD 3.29Å; L83-P87 WeakPolarHBondContact O-CG 3.5Å
84L93.6Very high93.7Very high62 Ų6253.8 Ų53.833%0.32530%0.295SS..Hα-helixtrans-78.5-42.3172.2-64.2173.8000112F19 S20 L23 I80 G81 F82 L88F19-L84 HydrophobicContact CD1-CD1 4.05Å; F19-L84 HydrophobicContact CE1-CD1 3.91Å; S20-L84 WeakPolarHBondContact OG-CB 3.35Å; L23-L84 HydrophobicContact CD1-CD1 4.42Å; I80-L84 HydrophobicContact CG2-CD1 4.31Å; I80-L84 WeakPolarHBondContact O-CG 3.33Å; I80-L84 PolarHBondContact O-N 2.9Å; I80-L84 VanDerWaalsContact O-N 3.1Å; G81-L84 PolarHBondContact O-N 2.98Å; F82-L84 PolarHBondContact O-N 2.77Å; L84-L88 WeakPolarHBondContact O-CD1 3.22Å; L84-L88 VanDerWaalsContact O-CG 3.31Å; L84-L88 WeakPolarHBondContact O-CG 3.33Å
85W93.3Very high93.6Very high15 Ų1553.4 Ų53.46%0.05729%0.292CS..Hα-helixtrans-69.3-42-174.3175.482.2000113.3H17 W21 I24 G81 F82 L88 Q89 Y397 F405H17-W85 AromaticContact CD2-CD1 3.63Å; H17-W85 AromaticContact CD2-NE1 3.75Å; H17-W85 AromaticContact NE2-CD1 3.81Å; H17-W85 AromaticContact NE2-NE1 3.53Å; W21-W85 AromaticContact CD1-CD1 3.9Å; W21-W85 AromaticContact CD1-NE1 3.84Å; W21-W85 AromaticContact NE1-NE1 3.61Å; I24-W85 HydrophobicContact CD1-CB 3.7Å; I24-W85 HydrophobicContact CD1-CD2 4.41Å; I24-W85 HydrophobicContact CD1-CG 3.94Å; G81-W85 WeakPolarHBondContact O-CB 3.35Å; G81-W85 PolarHBondContact O-N 2.87Å; F82-W85 AromaticContact CD2-CE3 3.92Å; F82-W85 HydrophobicContact CD2-CE3 3.92Å; F82-W85 HydrophobicContact CD2-CZ3 4.24Å; F82-W85 HydrophobicContact CE2-CE3 4.01Å; F82-W85 AromaticContact CE2-CZ3 3.92Å; F82-W85 HydrophobicContact CE2-CZ3 3.92Å; F82-W85 PolarHBondContact O-N 2.96Å; W85-L88 WeakPolarHBondContact O-CB 2.95Å; W85-L88 PolarHBondContact O-N 3.39Å; W85-Q89 VanDerWaalsContact CD1-NE2 3.28Å; W85-Q89 HydrophobicContact CD2-CG 4.07Å; W85-Q89 VanDerWaalsContact CE2-CD 3.45Å; W85-Q89 VanDerWaalsContact CE2-NE2 3.31Å; W85-Q89 HydrophobicContact CE3-CG 4.32Å; W85-Q89 HydrophobicContact CH2-CG 3.94Å; W85-Q89 HydrophobicContact CZ2-CG 3.66Å; W85-Q89 HydrophobicContact CZ3-CG 4.28Å; W85-Q89 WeakPolarHBondContact O-CG 3.46Å; W85-Q89 PolarHBondContact O-N 3.38Å; W85-Q89 PolarHBondContact O-NE2 3.11Å; W85-Y397 HydrophobicContact CH2-CD1 4.36Å; W85-Y397 HydrophobicContact CZ2-CD1 4.11Å; W85-Y397 HydrophobicContact CZ2-CG 4.22Å; W85-F405 HydrophobicContact CH2-CZ 4.5Å; W85-F405 HydrophobicContact CZ3-CE1 4.45Å; W85-F405 AromaticContact CZ3-CZ 3.86Å; W85-F405 HydrophobicContact CZ3-CZ 3.86Å
86S90.3Very high93.6Very high35 Ų3549.6 Ų49.625%0.24527%0.272CS..Hα-helixtrans-62-48.2-171.9174.90000113.1F82 L88 Q89F82-S86 VanDerWaalsContact O-CB 3.3Å; F82-S86 WeakPolarHBondContact O-CB 3.37Å; F82-S86 PolarHBondContact O-N 2.83Å; S86-L88 VanDerWaalsContact C-N 3.3Å; S86-L88 PolarHBondContact O-N 2.94Å; S86-Q89 WeakPolarHBondContact O-CB 3.47Å; S86-Q89 PolarHBondContact O-N 3.12Å
87P89.8Confident93.5Very high77 Ų7747.5 Ų47.550%0.525%0.254SS..Hα-helixtrans-61.4-34.4174.9-23.834.5000113.7L83 Q89 S90L83-P87 WeakPolarHBondContact O-CD 3.29Å; L83-P87 WeakPolarHBondContact O-CG 3.5Å; P87-Q89 PolarHBondContact O-N 3.04Å; P87-S90 WeakPolarHBondContact O-CB 3.28Å; P87-S90 PolarHBondContact O-N 2.8Å; P87-S90 VanDerWaalsContact O-N 3.15Å; P87-S90 PolarHBondContact O-OG 3.04Å
88L90.8Very high93.5Very high11 Ų1143 Ų436%0.05824%0.237CC..Hα-helixtrans-60.8-31178.8-62.7170.9000112F8 L13 L16 H17 L84 W85 S86 S90 A91 R92F8-L88 HydrophobicContact CE1-CB 4.16Å; F8-L88 WeakPolarHBondContact CE1-O 3.39Å; F8-L88 HydrophobicContact CZ-CB 4.43Å; L13-L88 HydrophobicContact CD2-CD2 3.55Å; L16-L88 HydrophobicContact CB-CD1 4.28Å; L16-L88 HydrophobicContact CD2-CD2 3.97Å; L16-L88 HydrophobicContact CG-CD1 4.02Å; L16-L88 HydrophobicContact CG-CD2 4.32Å; H17-L88 HydrophobicContact CB-CD1 3.94Å; L84-L88 WeakPolarHBondContact O-CD1 3.22Å; L84-L88 VanDerWaalsContact O-CG 3.31Å; L84-L88 WeakPolarHBondContact O-CG 3.33Å; W85-L88 WeakPolarHBondContact O-CB 2.95Å; W85-L88 PolarHBondContact O-N 3.39Å; S86-L88 VanDerWaalsContact C-N 3.3Å; S86-L88 PolarHBondContact O-N 2.94Å; L88-S90 PolarHBondContact O-N 3.27Å; L88-S90 VanDerWaalsContact O-N 3.09Å; L88-A91 PolarHBondContact O-N 2.73Å; L88-R92 PolarHBondContact O-N 3.22Å
89Q89.6Confident93.3Very high4 Ų448.6 Ų48.62%0.01926%0.256CS..THydrogen-bonded Turntrans-64.3-16.4-178.8-57.6-38.1-60.400113.1W85 S86 P87 S398W85-Q89 VanDerWaalsContact CD1-NE2 3.28Å; W85-Q89 HydrophobicContact CD2-CG 4.07Å; W85-Q89 VanDerWaalsContact CE2-CD 3.45Å; W85-Q89 VanDerWaalsContact CE2-NE2 3.31Å; W85-Q89 HydrophobicContact CE3-CG 4.32Å; W85-Q89 HydrophobicContact CH2-CG 3.94Å; W85-Q89 HydrophobicContact CZ2-CG 3.66Å; W85-Q89 HydrophobicContact CZ3-CG 4.28Å; W85-Q89 WeakPolarHBondContact O-CG 3.46Å; W85-Q89 PolarHBondContact O-N 3.38Å; W85-Q89 PolarHBondContact O-NE2 3.11Å; S86-Q89 WeakPolarHBondContact O-CB 3.47Å; S86-Q89 PolarHBondContact O-N 3.12Å; P87-Q89 PolarHBondContact O-N 3.04Å; Q89-S398 VanDerWaalsContact C-OG 3.31Å; Q89-S398 PolarHBondContact O-OG 2.88Å
90S86.3Confident92.8Very high73 Ų7347.3 Ų47.351%0.5125%0.249SC..THydrogen-bonded Turntrans-73.1-28.3172.167.90000113.3P87 L88 H400P87-S90 WeakPolarHBondContact O-CB 3.28Å; P87-S90 PolarHBondContact O-N 2.8Å; P87-S90 VanDerWaalsContact O-N 3.15Å; P87-S90 PolarHBondContact O-OG 3.04Å; L88-S90 PolarHBondContact O-N 3.27Å; L88-S90 VanDerWaalsContact O-N 3.09Å; S90-H400 PolarHBondContact O-CE1 3.48Å; S90-H400 VanDerWaalsContact O-CE1 3.3Å
91A90.4Very high91.2Very high40 Ų4050.1 Ų50.133%0.33126%0.261SS..SBendtrans-97.51177.800000112.7P9 L13 L88P9-A91 WeakPolarHBondContact CD-O 3.36Å; L13-A91 HydrophobicContact CD1-CB 4.02Å; L88-A91 PolarHBondContact O-N 2.73Å
92R91.1Very high89Confident20 Ų2057.2 Ų57.28%0.07530%0.298CS..  trans-74.4131.4-178.4-175.6169.9179.74.9-8.3110.1P7 F8 L88 D393P7-R92 VanDerWaalsContact CB-NH1 3.26Å; F8-R92 HydrophobicContact CD1-CB 4.39Å; F8-R92 HydrophobicContact CE1-CB 3.72Å; F8-R92 HydrophobicContact CE1-CG 4.16Å; F8-R92 HydrophobicContact CZ-CB 4.19Å; F8-R92 HydrophobicContact CZ-CG 4.23Å; L88-R92 PolarHBondContact O-N 3.22Å; R92-D393 IonicContact CZ-OD2 2.73Å; R92-D393 IonicContact NH2-OD1 2.69Å; R92-D393 IonicContact NH2-OD2 3.76Å; R92-D393 PolarHBondContact NH2-OD2 2.69Å
93R93.3Very high86.6Confident65 Ų6562.2 Ų62.225%0.24532%0.32CS..  trans-71150.1173.2-71.3159.7167.9-166.9-0.4110.6Y4 S6 P7 Y95Y4-R93 HydrophobicContact CD1-CG 3.98Å; Y4-R93 HydrophobicContact CD2-CB 4.06Å; Y4-R93 HydrophobicContact CD2-CG 4.32Å; Y4-R93 HydrophobicContact CE1-CG 4.29Å; Y4-R93 HydrophobicContact CG-CB 4.02Å; Y4-R93 HydrophobicContact CG-CG 3.99Å; S6-R93 WeakPolarHBondContact O-CD 3.33Å; S6-R93 PolarHBondContact O-NH1 3.47Å; P7-R93 PolarHBondContact O-N 2.6Å; R93-Y95 VanDerWaalsContact C-N 3.25Å; R93-Y95 PolarHBondContact O-N 2.82Å
94P93.4Very high84.1Confident32 Ų3261.6 Ų61.621%0.20833%0.325CS..SBendtrans-72.9-11.7-170.728.2-36.2000114.8Y4 V394 G395 V396 Y425Y4-P94 HydrophobicContact CD2-CG 4.41Å; Y4-P94 HydrophobicContact CE2-CG 4.13Å; P94-V394 CarbonylContact O-C 3.58Å; P94-V394 VanDerWaalsContact O-CA 3.29Å; P94-V394 WeakPolarHBondContact O-CA 3.45Å; P94-G395 PolarHBondContact O-N 2.92Å; P94-V396 HydrophobicContact CB-CG1 4.48Å; P94-Y425 HydrophobicContact CB-CD1 4.12Å
95Y95.8Very high81.3Confident3 Ų365.7 Ų65.71%0.01234%0.342CS..  trans-160.5172.9178.558.5-100.9000110.8L3 Y4 R93 I391 A423L3-Y95 HydrophobicContact CD2-CE2 4.34Å; Y4-Y95 HydrophobicContact CD2-CD1 4.45Å; Y4-Y95 HydrophobicContact CD2-CD2 4.25Å; Y4-Y95 AromaticContact CD2-CE1 3.97Å; Y4-Y95 HydrophobicContact CD2-CE1 3.97Å; Y4-Y95 AromaticContact CD2-CE2 3.74Å; Y4-Y95 HydrophobicContact CD2-CE2 3.74Å; Y4-Y95 AromaticContact CD2-CZ 3.58Å; Y4-Y95 HydrophobicContact CE2-CE1 4.19Å; Y4-Y95 HydrophobicContact CG-CE2 4.35Å; R93-Y95 VanDerWaalsContact C-N 3.25Å; R93-Y95 PolarHBondContact O-N 2.82Å; Y95-I391 HydrophobicContact CD2-CD1 4.42Å; Y95-I391 HydrophobicContact CD2-CG2 4.05Å; Y95-I391 HydrophobicContact CE2-CD1 4.38Å; Y95-I391 HydrophobicContact CG-CG2 4.05Å; Y95-A423 HydrophobicContact CE1-CB 4.06Å; Y95-A423 WeakPolarHBondContact CE1-O 3.41Å; Y95-A423 HydrophobicContact CE2-CB 4.28Å; Y95-A423 PolarHBondContact OH-O 2.89Å
96I96.3Very high78.6Confident11 Ų1170.1 Ų70.16%0.05638%0.383CS..EExtended strand (participates in β ladder)trans-124123.9170.5-52.9172000108.9Y4 P7 I391 Y392 D393Y4-I96 CarbonylContact O-C 3.11Å; Y4-I96 WeakPolarHBondContact O-CA 3.44Å; P7-I96 HydrophobicContact CB-CD1 4Å; P7-I96 HydrophobicContact CB-CG1 4.24Å; P7-I96 HydrophobicContact CG-CD1 4.19Å; I96-I391 CarbonylContact O-C 3.59Å; I96-I391 WeakPolarHBondContact O-CA 3.39Å; I96-Y392 HydrophobicContact CB-CD1 4.02Å; I96-Y392 HydrophobicContact CB-CE1 3.65Å; I96-Y392 HydrophobicContact CD1-CE1 4.43Å; I96-Y392 HydrophobicContact CD1-CE2 4.19Å; I96-Y392 HydrophobicContact CG2-CD1 4.27Å; I96-Y392 HydrophobicContact CG2-CE1 3.49Å; I96-Y392 VanDerWaalsContact CG2-CE1 3.49Å; I96-Y392 PolarHBondContact N-O 2.91Å; I96-Y392 WeakPolarHBondContact O-CD1 3.48Å; I96-Y392 PolarHBondContact O-N 3.18Å; I96-D393 HydrophobicContact CD1-CB 3.95Å; I96-D393 HydrophobicContact CG1-CB 4.33Å
97Y97.1Very high75.8Confident30 Ų3074.3 Ų74.312%0.11840%0.402CS..EExtended strand (participates in β ladder)trans-91.8122.7169.9169.5-111.5000109.4L3 Y4 T5 R99 Y389 I391 I420L3-Y97 HydrophobicContact CB-CD1 3.89Å; L3-Y97 HydrophobicContact CB-CE1 4.47Å; L3-Y97 HydrophobicContact CB-CG 4.04Å; L3-Y97 HydrophobicContact CD1-CD1 4.17Å; L3-Y97 HydrophobicContact CD1-CD2 4.18Å; L3-Y97 HydrophobicContact CD1-CE1 4.1Å; L3-Y97 HydrophobicContact CD1-CE2 4.1Å; L3-Y97 HydrophobicContact CD1-CG 4.2Å; Y4-Y97 PolarHBondContact O-N 3.02Å; T5-Y97 WeakPolarHBondContact CA-O 3.45Å; T5-Y97 HydrophobicContact CG2-CD1 3.96Å; Y97-R99 HydrophobicContact CE1-CB 4.29Å; Y97-Y389 HydrophobicContact CE2-CD1 4.07Å; Y97-Y389 WeakPolarHBondContact OH-CD1 3.33Å; Y97-I391 HydrophobicContact CD2-CG1 4.11Å; Y97-I420 HydrophobicContact CD2-CD1 4.27Å; Y97-I420 HydrophobicContact CE2-CB 4.37Å; Y97-I420 HydrophobicContact CE2-CD1 4.19Å
98S96.3Very high73.1Confident24 Ų2479.9 Ų79.917%0.16842%0.422CS..EExtended strand (participates in β ladder)trans-119.8123.5177.7-178.50000108.6H384 I390S98-H384 PolarHBondContact OG-NE2 3.32Å; S98-I390 PolarHBondContact N-O 3.26Å; S98-I390 PolarHBondContact O-N 2.83Å
99R93.3Very high70.5Confident132 Ų13283.6 Ų83.650%0.49845%0.454SS..EExtended strand (participates in β ladder)trans-108.9138.4170.4-172.7-178.8-178.3-178.81.2108.6Y97 E101 E388 Y389Y97-R99 HydrophobicContact CE1-CB 4.29Å; R99-E101 PolarHBondContact O-N 3.4Å; R99-E101 VanDerWaalsContact O-N 3.12Å; R99-E388 WeakPolarHBondContact CA-O 3.43Å; R99-E388 HydrophobicContact CG-CG 4.23Å; R99-E388 IonicContact CZ-OE1 3.79Å; R99-E388 VanDerWaalsContact CZ-OE1 3.28Å; R99-E388 IonicContact NE-OE1 2.64Å; R99-E388 PolarHBondContact NE-OE1 3.34Å; R99-E388 IonicContact NH2-OE1 3.76Å; R99-E388 PolarHBondContact NH2-OE1 2.86Å; R99-Y389 HydrophobicContact CG-CD1 4.1Å; R99-Y389 HydrophobicContact CG-CE1 3.99Å; R99-Y389 PolarHBondContact NH2-OH 3.07Å
100L86.6Confident68.2Low82 Ų8289.3 Ų89.343%0.42949%0.489SS..  trans-67.9106.6168.6-170.568.6000108.6H384 E388L100-H384 HydrophobicContact CD1-CB 4.27Å; L100-E388 HydrophobicContact CB-CG 4.43Å; L100-E388 PolarHBondContact N-O 3.08Å
101E62.9Low66.2Low149 Ų14993.2 Ų93.270%0.69650%0.503SS*.  trans-83126.3169.1-72.6-177167.900108.9R99 K103R99-E101 PolarHBondContact O-N 3.4Å; R99-E101 VanDerWaalsContact O-N 3.12Å; E101-K103 VanDerWaalsContact C-N 3.29Å; E101-K103 PolarHBondContact O-N 3.05Å
102D51.8Low64.7Low149 Ų14993.7 Ų93.780%0.79750%0.5SS*.  trans-59.184.7177-89.3-29.7000111.5S104D102-S104 PolarHBondContact O-N 3.18Å
103K43.4Very low63.2Low178 Ų17898.4 Ų98.477%0.77453%0.531SS*.  trans-88.894.8161.2-70.9-174.6-178.8176.70107E101E101-K103 VanDerWaalsContact C-N 3.29Å; E101-K103 PolarHBondContact O-N 3.05Å
104S39.8Very low62.1Low102 Ų10299.6 Ų99.671%0.71354%0.539SS*.SBendtrans60.190.1171.758.70000116D102D102-S104 PolarHBondContact O-N 3.18Å
105H36.2Very low61.6Low147 Ų14799 Ų9968%0.68153%0.533SS*.  -177.3110.6116.2-96.9-71.2000109N107H105-N107 PolarHBondContact O-N 3.5Å
106A35.3Very low61Low109 Ų109103 Ų10390%0.90155%0.551SS**  trans-68.164.716200000110.3
107N31.6Very low60.1Low122 Ų122103.3 Ų103.365%0.65256%0.555SS**SBendtrans-133.589.4168.3-84.7-12000107.7H105 A109H105-N107 PolarHBondContact O-N 3.5Å; N107-A109 VanDerWaalsContact C-N 3.34Å; N107-A109 PolarHBondContact O-N 2.82Å
108E33Very low58.6Low195 Ų195105.6 Ų105.691%0.91158%0.579SS**  trans36.551.8148.2-66.8178.1144.600116.9T110E108-T110 PolarHBondContact O-N 3.35Å; E108-T110 VanDerWaalsContact O-N 3.1Å
109A37.2Very low57.3Low89 Ų89105.6 Ų105.674%0.73658%0.584SS**  trans-66.7108.9151.100000105.2N107 L111N107-A109 VanDerWaalsContact C-N 3.34Å; N107-A109 PolarHBondContact O-N 2.82Å; A109-L111 VanDerWaalsContact C-N 3.3Å; A109-L111 PolarHBondContact O-N 3.29Å
110T41.6Very low56.1Low123 Ų123106 Ų10676%0.75560%0.596SS**  trans-44.793.1-179.9-35.50000109.6E108 L112E108-T110 PolarHBondContact O-N 3.35Å; E108-T110 VanDerWaalsContact O-N 3.1Å; T110-L112 PolarHBondContact O-N 3.27Å
111L44.4Very low56Low156 Ų156103.3 Ų103.382%0.81759%0.588SS**  trans-49113.5170.2-95.5163.1000104.7A109 T113A109-L111 VanDerWaalsContact C-N 3.3Å; A109-L111 PolarHBondContact O-N 3.29Å; L111-T113 PolarHBondContact O-N 3.23Å
112L58.1Low57.4Low49 Ų4999.1 Ų99.126%0.25757%0.567SS.*  trans-46.6113.6174-91.9172.2000105.9T110 E114 R417 Y418T110-L112 PolarHBondContact O-N 3.27Å; L112-E114 PolarHBondContact O-N 3.19Å; L112-R417 HydrophobicContact CD1-CB 3.48Å; L112-R417 VanDerWaalsContact CD1-CB 3.48Å; L112-R417 WeakPolarHBondContact CD1-O 3.3Å; L112-Y418 HydrophobicContact CD1-CD1 4.49Å; L112-Y418 HydrophobicContact CD1-CD2 4.46Å; L112-Y418 HydrophobicContact CD1-CE1 4.2Å; L112-Y418 HydrophobicContact CD1-CE2 4.13Å
113T58.9Low59.4Low119 Ų11993.3 Ų93.373%0.7354%0.538SS*.  trans-56.6112-179.6-40.20000105.9L111 W115L111-T113 PolarHBondContact O-N 3.23Å; T113-W115 PolarHBondContact O-N 2.98Å; T113-W115 VanDerWaalsContact O-N 3.11Å
114E71.3Confident61.9Low90 Ų9084.8 Ų84.842%0.42150%0.501SS..  trans-51.9122.6-176.2-172.8-179.2-164.300107.5L112 K116L112-E114 PolarHBondContact O-N 3.19Å; E114-K116 VanDerWaalsContact CD-NZ 3.31Å; E114-K116 PolarHBondContact O-N 2.88Å; E114-K116 IonicContact OE1-NZ 3.07Å; E114-K116 VanDerWaalsContact OE2-CE 3.31Å; E114-K116 WeakPolarHBondContact OE2-CE 3.4Å; E114-K116 IonicContact OE2-NZ 3.53Å; E114-K116 PolarHBondContact OE2-NZ 2.73Å
115W83.4Confident64.7Low21 Ų2180 Ų808%0.0847%0.468CS..BIsolated β-bridgetrans-67.4114.1-177.2175.538.8000108.4T113 A117 K122 F124 V449 G450 S451 I458 A508 W627 V655 T657T113-W115 PolarHBondContact O-N 2.98Å; T113-W115 VanDerWaalsContact O-N 3.11Å; W115-A117 HydrophobicContact CZ2-CB 4.27Å; W115-K122 HydrophobicContact CB-CD 4.48Å; W115-K122 HydrophobicContact CB-CG 4.48Å; W115-K122 HydrophobicContact CD2-CB 3.6Å; W115-K122 HydrophobicContact CD2-CG 3.95Å; W115-K122 HydrophobicContact CE3-CB 4.1Å; W115-K122 HydrophobicContact CE3-CG 4.28Å; W115-K122 HydrophobicContact CG-CB 3.97Å; W115-K122 HydrophobicContact CG-CD 4.26Å; W115-K122 HydrophobicContact CG-CG 4.03Å; W115-K122 HydrophobicContact CH2-CB 4.19Å; W115-K122 HydrophobicContact CZ2-CB 3.72Å; W115-K122 HydrophobicContact CZ3-CB 4.34Å; W115-F124 HydrophobicContact CD2-CZ 4.46Å; W115-F124 HydrophobicContact CE3-CE2 4.08Å; W115-F124 AromaticContact CE3-CZ 3.58Å; W115-F124 HydrophobicContact CE3-CZ 3.58Å; W115-F124 HydrophobicContact CH2-CE2 4.33Å; W115-F124 AromaticContact CZ3-CE2 3.7Å; W115-F124 HydrophobicContact CZ3-CE2 3.7Å; W115-F124 AromaticContact CZ3-CZ 3.66Å; W115-F124 HydrophobicContact CZ3-CZ 3.66Å; W115-V449 HydrophobicContact CE3-CG2 4.27Å; W115-V449 HydrophobicContact CZ3-CG2 4.34Å; W115-G450 CarbonylContact O-C 3.54Å; W115-G450 WeakPolarHBondContact O-CA 3.47Å; W115-S451 PolarHBondContact O-N 2.88Å; W115-I458 HydrophobicContact CD2-CD1 4.16Å; W115-I458 HydrophobicContact CE3-CD1 3.85Å; W115-I458 HydrophobicContact CE3-CG2 4.06Å; W115-I458 HydrophobicContact CH2-CG2 4.48Å; W115-I458 HydrophobicContact CZ3-CD1 4.11Å; W115-I458 HydrophobicContact CZ3-CG2 3.64Å; W115-A508 HydrophobicContact CZ3-CB 4.04Å; W115-W627 HydrophobicContact CH2-CE3 4.25Å; W115-W627 AromaticContact CH2-CH2 3.97Å; W115-W627 HydrophobicContact CH2-CH2 3.97Å; W115-W627 AromaticContact CH2-CZ3 3.82Å; W115-W627 HydrophobicContact CH2-CZ3 3.82Å; W115-W627 HydrophobicContact CZ3-CH2 4.3Å; W115-W627 HydrophobicContact CZ3-CZ3 4.14Å; W115-V655 HydrophobicContact CH2-CB 4.07Å; W115-V655 HydrophobicContact CH2-CG1 3.83Å; W115-T657 HydrophobicContact CZ2-CG2 4.39Å
116K82.3Confident67.7Low87 Ų8773.2 Ų73.238%0.37844%0.436SS..  trans-89.94.7-177.7-68.8-64.3176.5-169.20114.8E114 A118 S451 P453E114-K116 VanDerWaalsContact CD-NZ 3.31Å; E114-K116 PolarHBondContact O-N 2.88Å; E114-K116 IonicContact OE1-NZ 3.07Å; E114-K116 VanDerWaalsContact OE2-CE 3.31Å; E114-K116 WeakPolarHBondContact OE2-CE 3.4Å; E114-K116 IonicContact OE2-NZ 3.53Å; E114-K116 PolarHBondContact OE2-NZ 2.73Å; K116-A118 PolarHBondContact O-N 3.27Å; K116-S451 CarbonylContact C-O 3.4Å; K116-S451 WeakPolarHBondContact CA-O 3.1Å; K116-S451 WeakPolarHBondContact CD-OG 3.31Å; K116-S451 PolarHBondContact NZ-OG 3.48Å; K116-P453 WeakPolarHBondContact O-CD 3.49Å
117A78Confident70.7Confident17 Ų1768.1 Ų68.114%0.1439%0.394CS..  trans46.427.9-176.100000115.9W115 T452 I458 W627 T657W115-A117 HydrophobicContact CZ2-CB 4.27Å; A117-T452 HydrophobicContact CB-CG2 4.46Å; A117-I458 HydrophobicContact CB-CD1 3.61Å; A117-W627 HydrophobicContact CB-CZ2 4.09Å; A117-T657 HydrophobicContact CB-CG2 4.44Å
118A64.4Low73.9Confident77 Ų7762.3 Ų62.364%0.63636%0.363SS*.  trans-103.332.1-174.900000113.3K116 P453K116-A118 PolarHBondContact O-N 3.27Å; A118-P453 HydrophobicContact CB-CG 4.01Å
119G69.6Low77Confident25 Ų2553 Ų5326%0.25832%0.32SS..SBendtrans-175.2-165.4-177.300000112.6G121 T657G119-G121 PolarHBondContact O-N 2.9Å; G119-T657 PolarHBondContact O-OG1 3.42Å
120N69.3Low79.9Confident140 Ų14048.8 Ų48.875%0.74929%0.285SS*.SBendtrans-60.510.9-164.4-57.727.3000118.1
121G84Confident82.6Confident25 Ų2543 Ų4326%0.25825%0.249SC..  trans110.3-177.6178.600000115.1G119 V655G119-G121 PolarHBondContact O-N 2.9Å; G121-V655 CarbonylContact C-O 3.59Å; G121-V655 WeakPolarHBondContact CA-O 3.31Å
122K91.8Very high85.1Confident61 Ų6135.5 Ų35.527%0.26521%0.21SC..EExtended strand (participates in β ladder)trans-142.5132.1-178.8-177.371.5-179.4-175.90110.5W115 F124 V655W115-K122 HydrophobicContact CB-CD 4.48Å; W115-K122 HydrophobicContact CB-CG 4.48Å; W115-K122 HydrophobicContact CD2-CB 3.6Å; W115-K122 HydrophobicContact CD2-CG 3.95Å; W115-K122 HydrophobicContact CE3-CB 4.1Å; W115-K122 HydrophobicContact CE3-CG 4.28Å; W115-K122 HydrophobicContact CG-CB 3.97Å; W115-K122 HydrophobicContact CG-CD 4.26Å; W115-K122 HydrophobicContact CG-CG 4.03Å; W115-K122 HydrophobicContact CH2-CB 4.19Å; W115-K122 HydrophobicContact CZ2-CB 3.72Å; W115-K122 HydrophobicContact CZ3-CB 4.34Å; K122-F124 HydrophobicContact CB-CE2 4.05Å; K122-F124 HydrophobicContact CB-CZ 4.22Å; K122-F124 HydrophobicContact CG-CD2 4.45Å; K122-F124 HydrophobicContact CG-CE1 4.04Å; K122-F124 HydrophobicContact CG-CE2 3.82Å; K122-F124 HydrophobicContact CG-CZ 3.59Å; K122-V655 PolarHBondContact N-O 3.16Å; K122-V655 PolarHBondContact O-N 2.66Å
123S93.6Very high86.9Confident27 Ų2733.2 Ų33.219%0.18920%0.198CC..EExtended strand (participates in β ladder)trans-86.7136.1169.6-520000111.3E632 L653 M654S123-E632 WeakPolarHBondContact CB-OE2 3.18Å; S123-E632 PolarHBondContact OG-OE2 2.66Å; S123-L653 CarbonylContact C-O 3.59Å; S123-L653 VanDerWaalsContact CA-O 3.23Å; S123-L653 WeakPolarHBondContact CA-O 3.47Å; S123-M654 WeakPolarHBondContact OG-CE 3.24Å
124F96.6Very high88.6Confident0 Ų028.7 Ų28.70%017%0.169CC..EExtended strand (participates in β ladder)trans-118.3133.9171.9-64.6-77.1000110.3W115 K122 F126 D363 F364 Y418 V449 A508 F509 R652 L653 V655W115-F124 HydrophobicContact CD2-CZ 4.46Å; W115-F124 HydrophobicContact CE3-CE2 4.08Å; W115-F124 AromaticContact CE3-CZ 3.58Å; W115-F124 HydrophobicContact CE3-CZ 3.58Å; W115-F124 HydrophobicContact CH2-CE2 4.33Å; W115-F124 AromaticContact CZ3-CE2 3.7Å; W115-F124 HydrophobicContact CZ3-CE2 3.7Å; W115-F124 AromaticContact CZ3-CZ 3.66Å; W115-F124 HydrophobicContact CZ3-CZ 3.66Å; K122-F124 HydrophobicContact CB-CE2 4.05Å; K122-F124 HydrophobicContact CB-CZ 4.22Å; K122-F124 HydrophobicContact CG-CD2 4.45Å; K122-F124 HydrophobicContact CG-CE1 4.04Å; K122-F124 HydrophobicContact CG-CE2 3.82Å; K122-F124 HydrophobicContact CG-CZ 3.59Å; F124-F126 HydrophobicContact CB-CE2 3.66Å; F124-F126 HydrophobicContact CB-CZ 3.84Å; F124-F126 WeakPolarHBondContact O-CE2 3.42Å; F124-D363 WeakPolarHBondContact CA-OD2 3.07Å; F124-F364 HydrophobicContact CB-CE2 4.28Å; F124-F364 HydrophobicContact CD1-CE2 4.04Å; F124-F364 HydrophobicContact CD1-CZ 4.5Å; F124-Y418 HydrophobicContact CD1-CE2 4.21Å; F124-Y418 HydrophobicContact CE1-CE2 4.14Å; F124-Y418 AromaticContact CE1-CZ 3.97Å; F124-V449 HydrophobicContact CE1-CB 3.65Å; F124-V449 HydrophobicContact CE1-CG1 3.9Å; F124-V449 HydrophobicContact CE1-CG2 4.18Å; F124-V449 HydrophobicContact CZ-CB 3.79Å; F124-V449 HydrophobicContact CZ-CG1 4.36Å; F124-V449 HydrophobicContact CZ-CG2 3.8Å; F124-A508 HydrophobicContact CE2-CB 4.45Å; F124-F509 HydrophobicContact CB-CD1 4.37Å; F124-F509 HydrophobicContact CB-CE1 4.14Å; F124-F509 AromaticContact CD1-CE1 3.79Å; F124-F509 HydrophobicContact CD1-CE1 3.79Å; F124-F509 AromaticContact CD2-CD1 3.67Å; F124-F509 HydrophobicContact CD2-CD1 3.67Å; F124-F509 AromaticContact CD2-CE1 3.66Å; F124-F509 HydrophobicContact CD2-CE1 3.66Å; F124-F509 HydrophobicContact CE1-CE1 4.07Å; F124-F509 HydrophobicContact CE2-CD1 4.06Å; F124-F509 AromaticContact CE2-CE1 3.94Å; F124-F509 HydrophobicContact CE2-CE1 3.94Å; F124-F509 AromaticContact CG-CD1 3.96Å; F124-F509 HydrophobicContact CG-CD1 3.96Å; F124-F509 AromaticContact CG-CE1 3.57Å; F124-F509 HydrophobicContact CG-CE1 3.57Å; F124-F509 HydrophobicContact CZ-CE1 4.12Å; F124-R652 CarbonylContact O-C 2.93Å; F124-R652 VanDerWaalsContact O-CA 3.31Å; F124-R652 WeakPolarHBondContact O-CA 3.31Å; F124-L653 PolarHBondContact N-O 3.38Å; F124-L653 PolarHBondContact O-N 3.33Å; F124-V655 HydrophobicContact CD2-CG2 3.77Å; F124-V655 HydrophobicContact CE2-CB 4.4Å; F124-V655 HydrophobicContact CE2-CG2 3.87Å
125C97.8Very high89.7Confident1 Ų125.3 Ų25.31%0.00716%0.155CC..EExtended strand (participates in β ladder)trans-112.1125.8-177.2-168.90000112.2P359 N361 L362 D363 F364C125-P359 WeakPolarHBondContact SG-CG 3.3Å; C125-N361 VanDerWaalsContact CB-O 3.3Å; C125-N361 WeakPolarHBondContact CB-O 3.37Å; C125-L362 HydrophobicContact CB-CD1 4.44Å; C125-D363 PolarHBondContact N-OD2 3.04Å; C125-D363 WeakPolarHBondContact O-CA 3.08Å; C125-D363 WeakPolarHBondContact O-CB 3.3Å; C125-D363 PolarHBondContact O-N 2.93Å; C125-F364 PolarHBondContact O-N 3.34Å
126F98.8Very high90.1Very high5 Ų524.5 Ų24.52%0.02215%0.152CC..EExtended strand (participates in β ladder)trans-115.9138.7-177.2-54-94.6000109.7F124 F364 I462 F509 V511 M616 A650 M651 L653F124-F126 HydrophobicContact CB-CE2 3.66Å; F124-F126 HydrophobicContact CB-CZ 3.84Å; F124-F126 WeakPolarHBondContact O-CE2 3.42Å; F126-F364 CarbonylContact C-O 3.49Å; F126-F364 WeakPolarHBondContact CA-O 3.22Å; F126-F364 HydrophobicContact CD1-CB 3.9Å; F126-F364 AromaticContact CD1-CD2 3.54Å; F126-F364 HydrophobicContact CD1-CD2 3.54Å; F126-F364 HydrophobicContact CD1-CE2 4.45Å; F126-F364 HydrophobicContact CD1-CG 4.04Å; F126-F364 HydrophobicContact CE1-CB 4.4Å; F126-F364 AromaticContact CE1-CD2 3.28Å; F126-F364 HydrophobicContact CE1-CD2 3.28Å; F126-F364 AromaticContact CE1-CE2 3.78Å; F126-F364 HydrophobicContact CE1-CE2 3.78Å; F126-F364 HydrophobicContact CE1-CG 4.04Å; F126-F364 HydrophobicContact CG-CD2 4.3Å; F126-F364 AromaticContact CZ-CD2 3.86Å; F126-F364 HydrophobicContact CZ-CD2 3.86Å; F126-F364 HydrophobicContact CZ-CE2 4.01Å; F126-I462 HydrophobicContact CD1-CD1 4.36Å; F126-I462 HydrophobicContact CE1-CD1 3.97Å; F126-I462 HydrophobicContact CE1-CG1 4.06Å; F126-F509 AromaticContact CE1-CD2 3.86Å; F126-F509 HydrophobicContact CE1-CD2 3.86Å; F126-F509 AromaticContact CE1-CE2 3.64Å; F126-F509 HydrophobicContact CE1-CE2 3.64Å; F126-F509 HydrophobicContact CE1-CZ 4.13Å; F126-F509 HydrophobicContact CZ-CD1 4.05Å; F126-F509 AromaticContact CZ-CD2 3.59Å; F126-F509 HydrophobicContact CZ-CD2 3.59Å; F126-F509 HydrophobicContact CZ-CE1 4.11Å; F126-F509 AromaticContact CZ-CE2 3.66Å; F126-F509 HydrophobicContact CZ-CE2 3.66Å; F126-F509 AromaticContact CZ-CG 3.8Å; F126-F509 HydrophobicContact CZ-CG 3.8Å; F126-F509 AromaticContact CZ-CZ 3.92Å; F126-F509 HydrophobicContact CZ-CZ 3.92Å; F126-V511 HydrophobicContact CD1-CB 4.29Å; F126-V511 HydrophobicContact CD1-CG1 4.04Å; F126-V511 HydrophobicContact CD1-CG2 4.17Å; F126-V511 HydrophobicContact CD2-CG2 4.46Å; F126-V511 HydrophobicContact CE1-CB 4.2Å; F126-V511 HydrophobicContact CE1-CG1 4.45Å; F126-V511 HydrophobicContact CE1-CG2 3.83Å; F126-V511 HydrophobicContact CE2-CG2 4.16Å; F126-V511 HydrophobicContact CG-CG1 4.32Å; F126-V511 HydrophobicContact CG-CG2 4.48Å; F126-V511 HydrophobicContact CZ-CG2 3.84Å; F126-M616 HydrophobicContact CB-CE 4.08Å; F126-M616 HydrophobicContact CB-SD 3.79Å; F126-A650 CarbonylContact O-C 3.52Å; F126-A650 WeakPolarHBondContact O-CA 3.49Å; F126-A650 WeakPolarHBondContact O-CB 3.36Å; F126-M651 PolarHBondContact N-O 2.96Å; F126-M651 PolarHBondContact O-N 2.86Å; F126-L653 HydrophobicContact CD2-CD1 4.44Å; F126-L653 HydrophobicContact CD2-CG 4.37Å; F126-L653 HydrophobicContact CE2-CB 4.13Å; F126-L653 HydrophobicContact CE2-CD1 3.8Å; F126-L653 HydrophobicContact CE2-CG 3.96Å; F126-L653 HydrophobicContact CZ-CD1 4.38Å
127G98.6Very high90.5Very high1 Ų121 Ų211%0.0114%0.138CC..EExtended strand (participates in β ladder)trans-132.4143.8174.200000111.1F364 L365 C366 V649G127-F364 PolarHBondContact N-O 2.9Å; G127-L365 CarbonylContact O-C 3.48Å; G127-L365 WeakPolarHBondContact O-CA 3.36Å; G127-C366 PolarHBondContact O-N 3.18Å; G127-V649 CarbonylContact C-O 3.54Å; G127-V649 WeakPolarHBondContact CA-O 3.28Å
128S98.8Very high91.2Very high1 Ų124.1 Ų24.11%0.00715%0.152CC..EExtended strand (participates in β ladder)trans-130142.3172-169.80000111C366 Q368 P648 V649S128-C366 CarbonylContact C-O 3.55Å; S128-C366 WeakPolarHBondContact CA-O 3.46Å; S128-C366 PolarHBondContact OG-O 3.26Å; S128-Q368 PolarHBondContact OG-NE2 3.19Å; S128-Q368 VanDerWaalsContact OG-NE2 3.07Å; S128-Q368 PolarHBondContact OG-OE1 2.92Å; S128-P648 CarbonylContact O-C 3.51Å; S128-P648 WeakPolarHBondContact O-CA 3.39Å; S128-P648 WeakPolarHBondContact O-CB 3.44Å; S128-V649 PolarHBondContact N-O 3.44Å; S128-V649 PolarHBondContact O-N 3.46Å
129A98.3Very high92.6Very high0 Ų020.4 Ų20.40%012%0.122CC..EExtended strand (participates in β ladder)trans-153129.4174.300000113.2V131 C366 L367 Q368 L640 P648A129-V131 HydrophobicContact CB-CG1 4.07Å; A129-C366 PolarHBondContact N-O 2.78Å; A129-L367 HydrophobicContact CB-CD2 3.75Å; A129-L367 CarbonylContact O-C 3.56Å; A129-L367 VanDerWaalsContact O-CA 3.27Å; A129-L367 WeakPolarHBondContact O-CA 3.4Å; A129-Q368 PolarHBondContact O-N 2.91Å; A129-Q368 PolarHBondContact O-OE1 2.91Å; A129-L640 HydrophobicContact CB-CD1 4.5Å; A129-P648 HydrophobicContact CB-CB 3.71Å; A129-P648 HydrophobicContact CB-CG 3.72Å
130N98.4Very high93.7Very high0 Ų020.5 Ų20.50%011%0.114CC..EExtended strand (participates in β ladder)trans-78.3119.8159.4-172.2-21000109.1C132 Q368 E369 D515 T644 H646N130-C132 PolarHBondContact OD1-N 2.95Å; N130-C132 PolarHBondContact OD1-SG 3.11Å; N130-Q368 HydrophobicContact CB-CB 4.19Å; N130-E369 VanDerWaalsContact ND2-CD 3.28Å; N130-E369 WeakPolarHBondContact ND2-CG 3.23Å; N130-E369 PolarHBondContact ND2-OE1 3.29Å; N130-E369 VanDerWaalsContact OD1-CB 3.26Å; N130-E369 WeakPolarHBondContact OD1-CB 3.16Å; N130-E369 WeakPolarHBondContact OD1-CG 3.08Å; N130-D515 PolarHBondContact ND2-OD2 3.11Å; N130-T644 PolarHBondContact O-OG1 3.26Å; N130-H646 HydrophobicContact CB-CB 3.91Å
131V98.1Very high94.8Very high0 Ų020.2 Ų20.20%011%0.107CC..  trans-108.7-0.9-171.2-64.90000114.2A129 L133 R150 I154 L367 Q368 V370 L640A129-V131 HydrophobicContact CB-CG1 4.07Å; V131-L133 VanDerWaalsContact C-N 3.27Å; V131-L133 HydrophobicContact CB-CG 4.26Å; V131-L133 HydrophobicContact CG2-CB 4.39Å; V131-L133 HydrophobicContact CG2-CD1 3.85Å; V131-L133 HydrophobicContact CG2-CG 3.8Å; V131-L133 PolarHBondContact O-N 3.34Å; V131-L133 VanDerWaalsContact O-N 3.14Å; V131-R150 PolarHBondContact O-NH2 3.22Å; V131-I154 HydrophobicContact CB-CD1 4.13Å; V131-I154 HydrophobicContact CG1-CG2 3.99Å; V131-L367 HydrophobicContact CG1-CD2 4.05Å; V131-Q368 VanDerWaalsContact CG2-O 3.28Å; V131-Q368 WeakPolarHBondContact CG2-O 3.42Å; V131-Q368 PolarHBondContact N-O 2.82Å; V131-V370 HydrophobicContact CG2-CG2 3.69Å; V131-L640 HydrophobicContact CG1-CD1 4.33Å
132C96.5Very high95.1Very high0 Ų020.9 Ų20.90%011%0.105CC..  trans44.348.5176.7-59.50000114N130 L134 N142 V144 R150 E369 D645N130-C132 PolarHBondContact OD1-N 2.95Å; N130-C132 PolarHBondContact OD1-SG 3.11Å; C132-L134 HydrophobicContact CB-CD1 3.93Å; C132-L134 PolarHBondContact O-N 3.3Å; C132-N142 PolarHBondContact SG-ND2 3.08Å; C132-N142 VanDerWaalsContact SG-ND2 3.41Å; C132-V144 HydrophobicContact CB-CG2 4.25Å; C132-R150 PolarHBondContact O-NH1 3.25Å; C132-R150 PolarHBondContact O-NH2 3.43Å; C132-E369 WeakPolarHBondContact CA-OE2 3.36Å; C132-E369 PolarHBondContact SG-OE2 2.87Å; C132-D645 PolarHBondContact SG-OD1 3.2Å
133L97.2Very high95.2Very high0 Ų018.6 Ų18.60%010%0.095CC..  trans-90.557.9176.6-66.4179.3000110.4V131 T147 R150 A151 I154 E369 V370 F371 D372 A375 L379V131-L133 VanDerWaalsContact C-N 3.27Å; V131-L133 HydrophobicContact CB-CG 4.26Å; V131-L133 HydrophobicContact CG2-CB 4.39Å; V131-L133 HydrophobicContact CG2-CD1 3.85Å; V131-L133 HydrophobicContact CG2-CG 3.8Å; V131-L133 PolarHBondContact O-N 3.34Å; V131-L133 VanDerWaalsContact O-N 3.14Å; L133-T147 HydrophobicContact CB-CG2 4.09Å; L133-T147 HydrophobicContact CD2-CG2 3.93Å; L133-R150 HydrophobicContact CD2-CB 4.24Å; L133-A151 HydrophobicContact CD1-CB 3.82Å; L133-A151 HydrophobicContact CD2-CB 3.94Å; L133-I154 HydrophobicContact CD2-CD1 4.15Å; L133-E369 CarbonylContact C-O 3.6Å; L133-E369 WeakPolarHBondContact CA-O 3.33Å; L133-E369 WeakPolarHBondContact CB-O 3.43Å; L133-E369 PolarHBondContact N-O 2.83Å; L133-V370 HydrophobicContact CD1-CG1 4.38Å; L133-F371 PolarHBondContact O-N 2.77Å; L133-D372 PolarHBondContact O-N 3Å; L133-A375 HydrophobicContact CB-CB 4.39Å; L133-A375 HydrophobicContact CD1-CB 4.46Å; L133-L379 HydrophobicContact CD1-CD2 3.75Å
134L94.3Very high95.3Very high24 Ų2417.3 Ų17.313%0.1269%0.086CC..  trans-80.3164.8174.9-53.4115.1000110.9C132 D136 L138 A139 T147 E369 F371C132-L134 HydrophobicContact CB-CD1 3.93Å; C132-L134 PolarHBondContact O-N 3.3Å; L134-D136 PolarHBondContact O-N 2.8Å; L134-L138 HydrophobicContact CB-CB 3.89Å; L134-L138 HydrophobicContact CD2-CB 4.25Å; L134-A139 HydrophobicContact CB-CB 4.21Å; L134-A139 HydrophobicContact CD1-CB 4.42Å; L134-T147 WeakPolarHBondContact O-CB 3.35Å; L134-T147 WeakPolarHBondContact O-CG2 3.35Å; L134-T147 PolarHBondContact O-OG1 2.98Å; L134-E369 WeakPolarHBondContact CD1-OE2 3.16Å; L134-F371 HydrophobicContact CD2-CD2 3.72Å; L134-F371 HydrophobicContact CD2-CE2 3.93Å; L134-F371 HydrophobicContact CG-CD2 3.89Å; L134-F371 HydrophobicContact CG-CE2 4.43Å
135P93.3Very high95.1Very high19 Ų1918.6 Ų18.612%0.1239%0.092CC..  trans-43.3141.3158.5-27.534.9000110.8Y28 S137 L138 A139Y28-P135 HydrophobicContact CE2-CB 4.33Å; Y28-P135 HydrophobicContact CE2-CG 4.25Å; Y28-P135 VanDerWaalsContact OH-CB 3.29Å; Y28-P135 WeakPolarHBondContact OH-CB 3.34Å; Y28-P135 VanDerWaalsContact OH-CG 3.28Å; Y28-P135 WeakPolarHBondContact OH-CG 3.12Å; P135-S137 VanDerWaalsContact C-N 3.26Å; P135-S137 PolarHBondContact O-N 3.1Å; P135-L138 HydrophobicContact CB-CD1 4.47Å; P135-L138 HydrophobicContact CB-CG 4.42Å; P135-L138 HydrophobicContact CG-CD1 4.17Å; P135-L138 CarbonylContact O-C 3.52Å; P135-L138 WeakPolarHBondContact O-CA 3.46Å; P135-L138 WeakPolarHBondContact O-CB 3.38Å; P135-L138 PolarHBondContact O-N 3.37Å; P135-A139 PolarHBondContact O-N 2.77Å
136D91.6Very high94.9Very high5 Ų521 Ų213%0.02710%0.104CC..Hα-helixtrans-58.7-39.1-166.7-166.781.1000112.6D32 R33 L134 L138 A139 R140 N146D32-D136 PolarHBondContact OD1-N 3.13Å; D32-D136 VanDerWaalsContact OD1-N 3.12Å; R33-D136 IonicContact CZ-OD2 3.25Å; R33-D136 IonicContact NH1-OD2 2.97Å; R33-D136 IonicContact NH2-OD2 3.48Å; L134-D136 PolarHBondContact O-N 2.8Å; D136-L138 VanDerWaalsContact C-N 3.3Å; D136-L138 PolarHBondContact O-N 2.78Å; D136-A139 PolarHBondContact O-N 2.91Å; D136-R140 VanDerWaalsContact O-CD 3.29Å; D136-R140 WeakPolarHBondContact O-CD 3.14Å; D136-R140 WeakPolarHBondContact O-CG 3.48Å; D136-R140 PolarHBondContact O-N 2.86Å; D136-R140 VanDerWaalsContact O-N 3.13Å; D136-R140 IonicContact OD2-CZ 3.4Å; D136-R140 IonicContact OD2-NE 3.52Å; D136-R140 PolarHBondContact OD2-NE 3Å; D136-R140 IonicContact OD2-NH2 3.78Å; D136-N146 WeakPolarHBondContact OD1-CA 3.31Å; D136-N146 PolarHBondContact OD1-N 3.31Å
137S92Very high94.8Very high13 Ų1320.9 Ų20.99%0.09110%0.104CC..Hα-helixtrans-57.9-40173.352.30000113.3D32 P135 F141D32-S137 VanDerWaalsContact OD1-CB 3.29Å; D32-S137 WeakPolarHBondContact OD1-CB 3.22Å; D32-S137 PolarHBondContact OD1-N 3.2Å; D32-S137 PolarHBondContact OD1-OG 3.07Å; P135-S137 VanDerWaalsContact C-N 3.26Å; P135-S137 PolarHBondContact O-N 3.1Å; S137-F141 WeakPolarHBondContact O-CD2 3.34Å; S137-F141 WeakPolarHBondContact O-CE2 3.3Å
138L92.4Very high94.6Very high82 Ų8222.6 Ų22.643%0.42911%0.112SC..Hα-helixtrans-77.3-40178.5-64.7-175.4000111.5L134 P135 D136 R140 F141L134-L138 HydrophobicContact CB-CB 3.89Å; L134-L138 HydrophobicContact CD2-CB 4.25Å; P135-L138 HydrophobicContact CB-CD1 4.47Å; P135-L138 HydrophobicContact CB-CG 4.42Å; P135-L138 HydrophobicContact CG-CD1 4.17Å; P135-L138 CarbonylContact O-C 3.52Å; P135-L138 WeakPolarHBondContact O-CA 3.46Å; P135-L138 WeakPolarHBondContact O-CB 3.38Å; P135-L138 PolarHBondContact O-N 3.37Å; D136-L138 VanDerWaalsContact C-N 3.3Å; D136-L138 PolarHBondContact O-N 2.78Å; L138-R140 PolarHBondContact O-N 3.24Å; L138-F141 HydrophobicContact CD2-CE2 4.41Å; L138-F141 WeakPolarHBondContact O-CB 3.43Å; L138-F141 PolarHBondContact O-N 2.87Å
139A93.6Very high94.5Very high0 Ų024.1 Ų24.10%012%0.124CC..Hα-helixtrans-56.1-35176.600000111.5L134 P135 D136 F141 N142 V144L134-A139 HydrophobicContact CB-CB 4.21Å; L134-A139 HydrophobicContact CD1-CB 4.42Å; P135-A139 PolarHBondContact O-N 2.77Å; D136-A139 PolarHBondContact O-N 2.91Å; A139-F141 PolarHBondContact O-N 2.84Å; A139-N142 CarbonylContact O-C 3.55Å; A139-N142 PolarHBondContact O-N 2.79Å; A139-V144 CarbonylContact C-O 3.55Å; A139-V144 HydrophobicContact CB-CG2 4.1Å; A139-V144 WeakPolarHBondContact CB-O 3.41Å; A139-V144 WeakPolarHBondContact O-CG2 3.15Å; A139-V144 PolarHBondContact O-N 2.88Å; A139-V144 VanDerWaalsContact O-N 3.12Å; A139-V144 VanDerWaalsContact O-O 3.04Å
140R93.8Very high94.5Very high27 Ų2724.2 Ų24.210%0.10213%0.125CC..G310 helixtrans-64.2-21.8179.6-73.7159.6171.7-77.3-6.5113.9V39 T41 E44 D136 L138 N142 N143 V144 F145V39-R140 HydrophobicContact CB-CB 4.17Å; V39-R140 HydrophobicContact CG1-CB 3.79Å; V39-R140 WeakPolarHBondContact O-CD 3.18Å; V39-R140 PolarHBondContact O-NH1 2.89Å; T41-R140 HydrophobicContact CG2-CG 4.14Å; E44-R140 VanDerWaalsContact CD-NH1 3.3Å; E44-R140 IonicContact OE1-CZ 3.01Å; E44-R140 IonicContact OE1-NH1 3.77Å; E44-R140 PolarHBondContact OE1-NH1 2.97Å; E44-R140 IonicContact OE1-NH2 2.72Å; E44-R140 PolarHBondContact OE1-NH2 3.24Å; E44-R140 IonicContact OE2-CZ 3.53Å; E44-R140 IonicContact OE2-NH1 3.85Å; E44-R140 PolarHBondContact OE2-NH1 2.63Å; E44-R140 IonicContact OE2-NH2 3.78Å; D136-R140 VanDerWaalsContact O-CD 3.29Å; D136-R140 WeakPolarHBondContact O-CD 3.14Å; D136-R140 WeakPolarHBondContact O-CG 3.48Å; D136-R140 PolarHBondContact O-N 2.86Å; D136-R140 VanDerWaalsContact O-N 3.13Å; D136-R140 IonicContact OD2-CZ 3.4Å; D136-R140 IonicContact OD2-NE 3.52Å; D136-R140 PolarHBondContact OD2-NE 3Å; D136-R140 IonicContact OD2-NH2 3.78Å; L138-R140 PolarHBondContact O-N 3.24Å; R140-N142 VanDerWaalsContact C-N 3.31Å; R140-N143 WeakPolarHBondContact O-CA 3.34Å; R140-N143 PolarHBondContact O-N 2.86Å; R140-N143 VanDerWaalsContact O-N 3.07Å; R140-V144 VanDerWaalsContact CA-O 3.28Å; R140-V144 WeakPolarHBondContact CA-O 3.09Å; R140-V144 PolarHBondContact N-O 2.88Å; R140-F145 HydrophobicContact CG-CB 4.32Å
141F90.9Very high94.5Very high133 Ų13324.2 Ų24.258%0.58313%0.125SC*.G310 helixtrans-70.6-28.9172.2-70-81.5000112.5V39 S137 L138 A139 N143V39-F141 HydrophobicContact CG1-CE1 4.42Å; V39-F141 HydrophobicContact CG1-CZ 4.48Å; V39-F141 HydrophobicContact CG2-CZ 4.14Å; S137-F141 WeakPolarHBondContact O-CD2 3.34Å; S137-F141 WeakPolarHBondContact O-CE2 3.3Å; L138-F141 HydrophobicContact CD2-CE2 4.41Å; L138-F141 WeakPolarHBondContact O-CB 3.43Å; L138-F141 PolarHBondContact O-N 2.87Å; A139-F141 PolarHBondContact O-N 2.84Å; F141-N143 PolarHBondContact O-N 2.76Å
142N90.9Very high94.5Very high40 Ų4029.1 Ų29.121%0.21415%0.146CC..G310 helixtrans-86.518169.4-64.423.4000111.3C132 A139 R140 V144 D645C132-N142 PolarHBondContact SG-ND2 3.08Å; C132-N142 VanDerWaalsContact SG-ND2 3.41Å; A139-N142 CarbonylContact O-C 3.55Å; A139-N142 PolarHBondContact O-N 2.79Å; R140-N142 VanDerWaalsContact C-N 3.31Å; N142-V144 HydrophobicContact CB-CG2 4.03Å; N142-V144 PolarHBondContact O-N 2.81Å; N142-D645 PolarHBondContact ND2-OD2 2.94Å
143N94.6Very high94.6Very high12 Ų1230.4 Ų30.46%0.06415%0.152CC..THydrogen-bonded Turntrans55.532.3-176.9-162.241.6000114.3T41 T42 R140 F141 P559 Y563T41-N143 WeakPolarHBondContact CA-OD1 3.26Å; T41-N143 VanDerWaalsContact CB-OD1 3.3Å; T41-N143 WeakPolarHBondContact CB-OD1 3.39Å; T42-N143 PolarHBondContact N-OD1 2.94Å; T42-N143 PolarHBondContact OG1-ND2 3Å; R140-N143 WeakPolarHBondContact O-CA 3.34Å; R140-N143 PolarHBondContact O-N 2.86Å; R140-N143 VanDerWaalsContact O-N 3.07Å; F141-N143 PolarHBondContact O-N 2.76Å; N143-P559 HydrophobicContact CB-CB 3.73Å; N143-P559 PolarHBondContact ND2-O 2.76Å; N143-Y563 WeakPolarHBondContact O-CE2 3.44Å; N143-Y563 PolarHBondContact O-OH 3.08Å
144V94.5Very high94.6Very high0 Ų030.4 Ų30.40%015%0.152CC..  trans-124.9147177-73.10000112.1C132 A139 R140 N142 R150 L562 Y563C132-V144 HydrophobicContact CB-CG2 4.25Å; A139-V144 CarbonylContact C-O 3.55Å; A139-V144 HydrophobicContact CB-CG2 4.1Å; A139-V144 WeakPolarHBondContact CB-O 3.41Å; A139-V144 WeakPolarHBondContact O-CG2 3.15Å; A139-V144 PolarHBondContact O-N 2.88Å; A139-V144 VanDerWaalsContact O-N 3.12Å; A139-V144 VanDerWaalsContact O-O 3.04Å; R140-V144 VanDerWaalsContact CA-O 3.28Å; R140-V144 WeakPolarHBondContact CA-O 3.09Å; R140-V144 PolarHBondContact N-O 2.88Å; N142-V144 HydrophobicContact CB-CG2 4.03Å; N142-V144 PolarHBondContact O-N 2.81Å; V144-R150 VanDerWaalsContact CB-NH1 3.32Å; V144-L562 HydrophobicContact CG1-CD2 3.35Å; V144-Y563 WeakPolarHBondContact CA-OH 3.41Å
145F92.9Very high94.8Very high27 Ų2729.2 Ų29.212%0.11815%0.146CC..  trans-140.2172-175.570.1-77000111.7T41 Y43 R140 R150 Y563T41-F145 HydrophobicContact CG2-CB 4.01Å; T41-F145 HydrophobicContact CG2-CD1 3.85Å; T41-F145 HydrophobicContact CG2-CG 4.28Å; Y43-F145 AromaticContact CD1-CE1 3.89Å; Y43-F145 HydrophobicContact CD1-CE1 3.89Å; Y43-F145 AromaticContact CD1-CZ 3.68Å; Y43-F145 HydrophobicContact CD1-CZ 3.68Å; Y43-F145 HydrophobicContact CE1-CZ 4.02Å; Y43-F145 HydrophobicContact CG-CE1 4.25Å; Y43-F145 HydrophobicContact CG-CZ 4.42Å; R140-F145 HydrophobicContact CG-CB 4.32Å; F145-R150 WeakPolarHBondContact O-CD 3.29Å; F145-Y563 WeakPolarHBondContact CD1-OH 3.34Å; F145-Y563 HydrophobicContact CE1-CE1 4.38Å; F145-Y563 AromaticContact CE1-CZ 3.99Å
146N93.3Very high95.1Very high51 Ų5132.9 Ų32.927%0.27316%0.157SC..  trans60.348.4-178.6-71.7-20.2000113.3D136 Q148 A149 R150 I247D136-N146 WeakPolarHBondContact OD1-CA 3.31Å; D136-N146 PolarHBondContact OD1-N 3.31Å; N146-Q148 PolarHBondContact O-N 3.42Å; N146-A149 HydrophobicContact CB-CB 4.46Å; N146-A149 PolarHBondContact O-N 3.18Å; N146-R150 PolarHBondContact O-N 2.82Å; N146-I247 HydrophobicContact CB-CD1 4.35Å; N146-I247 HydrophobicContact CB-CG2 4.15Å
147T95.9Very high95.4Very high4 Ų433.8 Ų33.83%0.02516%0.16CC..Hα-helixtrans-43.5-45-177.4-55.10000113.5L133 L134 A149 R150 A151 D372 A375L133-T147 HydrophobicContact CB-CG2 4.09Å; L133-T147 HydrophobicContact CD2-CG2 3.93Å; L134-T147 WeakPolarHBondContact O-CB 3.35Å; L134-T147 WeakPolarHBondContact O-CG2 3.35Å; L134-T147 PolarHBondContact O-OG1 2.98Å; T147-A149 PolarHBondContact O-N 3.1Å; T147-R150 PolarHBondContact O-N 3.12Å; T147-A151 WeakPolarHBondContact O-CB 3.3Å; T147-A151 PolarHBondContact O-N 3.01Å; T147-D372 HydrophobicContact CG2-CB 4.17Å; T147-A375 HydrophobicContact CG2-CB 3.71Å
148Q96Very high95.7Very high37 Ų3733.2 Ų33.217%0.17316%0.156CC..Hα-helixtrans-63.3-40.7-177.5-65.2-58.9-49.700113.8N146 D372 K378N146-Q148 PolarHBondContact O-N 3.42Å; Q148-D372 VanDerWaalsContact NE2-CG 3.34Å; Q148-D372 PolarHBondContact NE2-OD1 3.29Å; Q148-K378 HydrophobicContact CB-CD 4.39Å
149A96.7Very high95.8Very high32 Ų3231.5 Ų31.526%0.26414%0.144SC..Hα-helixtrans-80.8-38.7-179.700000111.1N146 T147 A151 K152 E153 I247N146-A149 HydrophobicContact CB-CB 4.46Å; N146-A149 PolarHBondContact O-N 3.18Å; T147-A149 PolarHBondContact O-N 3.1Å; A149-A151 VanDerWaalsContact C-N 3.26Å; A149-A151 PolarHBondContact O-N 3.23Å; A149-K152 PolarHBondContact O-N 3.41Å; A149-E153 PolarHBondContact O-N 3.05Å; A149-I247 HydrophobicContact CB-CG2 3.22Å
150R97.3Very high95.9Very high3 Ų334.3 Ų34.31%0.01116%0.159CC..Hα-helixtrans-53.5-44.4169.7-80.6176.955.7-137.5-5.1111.3V131 C132 L133 V144 F145 N146 T147 K152 E153 I154 L643V131-R150 PolarHBondContact O-NH2 3.22Å; C132-R150 PolarHBondContact O-NH1 3.25Å; C132-R150 PolarHBondContact O-NH2 3.43Å; L133-R150 HydrophobicContact CD2-CB 4.24Å; V144-R150 VanDerWaalsContact CB-NH1 3.32Å; F145-R150 WeakPolarHBondContact O-CD 3.29Å; N146-R150 PolarHBondContact O-N 2.82Å; T147-R150 PolarHBondContact O-N 3.12Å; R150-K152 PolarHBondContact O-N 2.85Å; R150-E153 PolarHBondContact O-N 3.18Å; R150-E153 VanDerWaalsContact O-N 3.16Å; R150-I154 HydrophobicContact CB-CD1 4.37Å; R150-I154 VanDerWaalsContact O-CB 3.32Å; R150-I154 WeakPolarHBondContact O-CB 3.29Å; R150-I154 WeakPolarHBondContact O-CG1 3.31Å; R150-I154 PolarHBondContact O-N 3.04Å; R150-L643 HydrophobicContact CG-CD2 4.21Å; R150-L643 PolarHBondContact NE-O 3.18Å; R150-L643 PolarHBondContact NH2-O 2.89Å
151A98.4Very high95.9Very high0 Ų033 Ų330%015%0.154CC..Hα-helixtrans-58.1-45178.300000113.4L133 T147 A149 G155 A375 K378 L379L133-A151 HydrophobicContact CD1-CB 3.82Å; L133-A151 HydrophobicContact CD2-CB 3.94Å; T147-A151 WeakPolarHBondContact O-CB 3.3Å; T147-A151 PolarHBondContact O-N 3.01Å; A149-A151 VanDerWaalsContact C-N 3.26Å; A149-A151 PolarHBondContact O-N 3.23Å; A151-G155 PolarHBondContact O-N 2.84Å; A151-G155 VanDerWaalsContact O-N 3.09Å; A151-A375 HydrophobicContact CB-CB 3.77Å; A151-A375 VanDerWaalsContact CB-O 3.31Å; A151-A375 WeakPolarHBondContact CB-O 3.44Å; A151-K378 HydrophobicContact CB-CB 4.43Å; A151-L379 HydrophobicContact CB-CB 4.3Å
152K98.1Very high96.1Very high102 Ų10226.7 Ų26.744%0.44313%0.127SC..Hα-helixtrans-62-46.3174.6-69.8-175.2175.6-175.50111.1A149 R150 G155 R156 K378A149-K152 PolarHBondContact O-N 3.41Å; R150-K152 PolarHBondContact O-N 2.85Å; K152-G155 PolarHBondContact O-N 2.79Å; K152-R156 WeakPolarHBondContact O-CB 3.43Å; K152-R156 PolarHBondContact O-N 3.08Å; K152-K378 HydrophobicContact CD-CD 4.42Å; K152-K378 HydrophobicContact CG-CB 3.85Å; K152-K378 HydrophobicContact CG-CD 4.14Å; K152-K378 HydrophobicContact CG-CG 4.19Å
153E98.3Very high96.1Very high27 Ų2728 Ų2813%0.12614%0.139CC..Hα-helixtrans-67.2-42.7-177.5177.660.6-169.900112.4A149 R150 R156 R157 L643A149-E153 PolarHBondContact O-N 3.05Å; R150-E153 PolarHBondContact O-N 3.18Å; R150-E153 VanDerWaalsContact O-N 3.16Å; E153-R156 VanDerWaalsContact CD-NH2 3.26Å; E153-R156 WeakPolarHBondContact O-CB 3.49Å; E153-R156 PolarHBondContact O-N 2.75Å; E153-R156 IonicContact OE1-CZ 3.65Å; E153-R156 IonicContact OE1-NE 3.28Å; E153-R156 IonicContact OE1-NH2 2.75Å; E153-R156 PolarHBondContact OE1-NH2 3.21Å; E153-R156 IonicContact OE2-CZ 2.71Å; E153-R156 VanDerWaalsContact OE2-CZ 3.31Å; E153-R156 IonicContact OE2-NE 4Å; E153-R156 PolarHBondContact OE2-NE 3.4Å; E153-R156 IonicContact OE2-NH2 2.67Å; E153-R156 PolarHBondContact OE2-NH2 3.39Å; E153-R156 VanDerWaalsContact OE2-NH2 3.08Å; E153-R157 WeakPolarHBondContact O-CG 3.36Å; E153-R157 PolarHBondContact O-N 2.63Å; E153-R157 IonicContact OE1-CZ 3.04Å; E153-R157 IonicContact OE1-NE 3.76Å; E153-R157 PolarHBondContact OE1-NE 3.37Å; E153-R157 IonicContact OE1-NH2 3.98Å; E153-R157 PolarHBondContact OE1-NH2 3.22Å; E153-L643 HydrophobicContact CB-CD1 4.42Å; E153-L643 HydrophobicContact CG-CD1 3.62Å; E153-L643 HydrophobicContact CG-CD2 4.02Å; E153-L643 HydrophobicContact CG-CG 4.49Å
154I98.7Very high95.9Very high0 Ų032 Ų320%015%0.153CC..Hα-helixtrans-58.5-51.8175.2-71.5169.1000109.7V131 L133 R150 R156 R157 I158 L379 L640 L643V131-I154 HydrophobicContact CB-CD1 4.13Å; V131-I154 HydrophobicContact CG1-CG2 3.99Å; L133-I154 HydrophobicContact CD2-CD1 4.15Å; R150-I154 HydrophobicContact CB-CD1 4.37Å; R150-I154 VanDerWaalsContact O-CB 3.32Å; R150-I154 WeakPolarHBondContact O-CB 3.29Å; R150-I154 WeakPolarHBondContact O-CG1 3.31Å; R150-I154 PolarHBondContact O-N 3.04Å; I154-R156 VanDerWaalsContact C-N 3.31Å; I154-R156 PolarHBondContact O-N 2.82Å; I154-R157 PolarHBondContact O-N 3.01Å; I154-I158 HydrophobicContact CG2-CD1 3.62Å; I154-I158 HydrophobicContact CG2-CG1 4.42Å; I154-I158 VanDerWaalsContact O-CG1 3.29Å; I154-I158 WeakPolarHBondContact O-CG1 3.33Å; I154-I158 PolarHBondContact O-N 3.32Å; I154-L379 HydrophobicContact CG2-CD1 4.14Å; I154-L640 HydrophobicContact CB-CD2 4.49Å; I154-L640 HydrophobicContact CG1-CD2 4.37Å; I154-L640 HydrophobicContact CG2-CD1 4.13Å; I154-L640 HydrophobicContact CG2-CD2 4.21Å; I154-L643 HydrophobicContact CD1-CB 4.23Å; I154-L643 HydrophobicContact CG1-CB 3.91Å; I154-L643 HydrophobicContact CG1-CD1 3.9Å
155G98.3Very high95.1Very high0 Ų037 Ų370%019%0.186CC..Hα-helixtrans-58.8-42177.300000112.7A151 K152 R159 L379A151-G155 PolarHBondContact O-N 2.84Å; A151-G155 VanDerWaalsContact O-N 3.09Å; K152-G155 PolarHBondContact O-N 2.79Å; G155-R159 VanDerWaalsContact O-CB 3.3Å; G155-R159 WeakPolarHBondContact O-CB 3.36Å; G155-R159 PolarHBondContact O-N 3.27Å; G155-L379 VanDerWaalsContact CA-CD1 3.49Å
156R98Very high93.9Very high96 Ų9639.9 Ų39.936%0.36220%0.199SC..Hα-helixtrans-61.1-46175.4-171.3-169.371.284.80.7112K152 E153 I154 N160K152-R156 WeakPolarHBondContact O-CB 3.43Å; K152-R156 PolarHBondContact O-N 3.08Å; E153-R156 VanDerWaalsContact CD-NH2 3.26Å; E153-R156 WeakPolarHBondContact O-CB 3.49Å; E153-R156 PolarHBondContact O-N 2.75Å; E153-R156 IonicContact OE1-CZ 3.65Å; E153-R156 IonicContact OE1-NE 3.28Å; E153-R156 IonicContact OE1-NH2 2.75Å; E153-R156 PolarHBondContact OE1-NH2 3.21Å; E153-R156 IonicContact OE2-CZ 2.71Å; E153-R156 VanDerWaalsContact OE2-CZ 3.31Å; E153-R156 IonicContact OE2-NE 4Å; E153-R156 PolarHBondContact OE2-NE 3.4Å; E153-R156 IonicContact OE2-NH2 2.67Å; E153-R156 PolarHBondContact OE2-NH2 3.39Å; E153-R156 VanDerWaalsContact OE2-NH2 3.08Å; I154-R156 VanDerWaalsContact C-N 3.31Å; I154-R156 PolarHBondContact O-N 2.82Å; R156-N160 PolarHBondContact NH1-ND2 3.25Å; R156-N160 VanDerWaalsContact O-CB 3.24Å; R156-N160 WeakPolarHBondContact O-CB 3.34Å; R156-N160 PolarHBondContact O-N 3.01Å; R156-N160 PolarHBondContact O-OD1 3.01Å
157R98.2Very high92.7Very high24 Ų2443.8 Ų43.89%0.09122%0.219CC..Hα-helixtrans-66.1-46-179.8-72.2-164.1-169.5177.66.8111.6E153 I154 N160 G161 Q639 L640 A641 L643E153-R157 WeakPolarHBondContact O-CG 3.36Å; E153-R157 PolarHBondContact O-N 2.63Å; E153-R157 IonicContact OE1-CZ 3.04Å; E153-R157 IonicContact OE1-NE 3.76Å; E153-R157 PolarHBondContact OE1-NE 3.37Å; E153-R157 IonicContact OE1-NH2 3.98Å; E153-R157 PolarHBondContact OE1-NH2 3.22Å; I154-R157 PolarHBondContact O-N 3.01Å; R157-N160 PolarHBondContact O-N 3.48Å; R157-G161 PolarHBondContact O-N 3.11Å; R157-Q639 HydrophobicContact CB-CG 4.23Å; R157-Q639 WeakPolarHBondContact CD-O 3.33Å; R157-Q639 PolarHBondContact NH1-O 3.04Å; R157-Q639 PolarHBondContact O-NE2 3.5Å; R157-Q639 PolarHBondContact O-OE1 3.16Å; R157-L640 HydrophobicContact CB-CD2 4.08Å; R157-A641 PolarHBondContact NH1-O 2.86Å; R157-A641 VanDerWaalsContact NH1-O 3.08Å; R157-L643 VanDerWaalsContact CZ-CD1 3.48Å
158I98.3Very high90.9Very high0 Ų049 Ų490%024%0.241CC..Hα-helixtrans-57-54.2176.5-69167.7000110.2I154 N160 G161 A162 F358 L365 L367 L383 F387 L640I154-I158 HydrophobicContact CG2-CD1 3.62Å; I154-I158 HydrophobicContact CG2-CG1 4.42Å; I154-I158 VanDerWaalsContact O-CG1 3.29Å; I154-I158 WeakPolarHBondContact O-CG1 3.33Å; I154-I158 PolarHBondContact O-N 3.32Å; I158-N160 VanDerWaalsContact C-N 3.32Å; I158-N160 PolarHBondContact O-N 2.79Å; I158-G161 PolarHBondContact O-N 2.9Å; I158-G161 VanDerWaalsContact O-N 3.13Å; I158-A162 WeakPolarHBondContact O-CB 2.96Å; I158-A162 PolarHBondContact O-N 3.48Å; I158-F358 HydrophobicContact CB-CD2 4.4Å; I158-F358 HydrophobicContact CB-CE2 4.41Å; I158-F358 HydrophobicContact CD1-CE2 4.42Å; I158-F358 HydrophobicContact CD1-CZ 4.25Å; I158-F358 HydrophobicContact CG1-CD2 3.91Å; I158-F358 HydrophobicContact CG1-CE1 4.33Å; I158-F358 HydrophobicContact CG1-CE2 3.46Å; I158-F358 VanDerWaalsContact CG1-CE2 3.46Å; I158-F358 HydrophobicContact CG1-CZ 3.7Å; I158-L365 HydrophobicContact CD1-CD2 4.2Å; I158-L365 HydrophobicContact CG2-CD2 3.75Å; I158-L367 HydrophobicContact CD1-CD2 4.43Å; I158-L383 HydrophobicContact CB-CD2 4.16Å; I158-L383 HydrophobicContact CD1-CD2 4.47Å; I158-L383 HydrophobicContact CG2-CD2 3.81Å; I158-F387 HydrophobicContact CG2-CE2 4.41Å; I158-L640 HydrophobicContact CG1-CD2 4.39Å
159R95.3Very high89.4Confident46 Ų4653.8 Ų53.817%0.17427%0.266CS..Hα-helixtrans-54-50.5177.4178.1-169.370.8-146.82.8111.3G155 G161 A162 S163 H385G155-R159 VanDerWaalsContact O-CB 3.3Å; G155-R159 WeakPolarHBondContact O-CB 3.36Å; G155-R159 PolarHBondContact O-N 3.27Å; R159-G161 PolarHBondContact O-N 2.93Å; R159-A162 PolarHBondContact O-N 2.72Å; R159-S163 VanDerWaalsContact O-CB 3.31Å; R159-S163 WeakPolarHBondContact O-CB 3.07Å; R159-S163 PolarHBondContact O-N 2.75Å; R159-S163 PolarHBondContact O-OG 3.13Å; R159-S163 VanDerWaalsContact O-OG 3.08Å; R159-H385 VanDerWaalsContact CD-CB 3.41Å; R159-H385 HydrophobicContact CG-CB 4.43Å; R159-H385 PolarHBondContact NH1-CD2 2.83Å
160N95.2Very high87.1Confident60 Ų6061 Ų6132%0.32129%0.288SS..Hα-helixtrans-64.9-28.8-177.4-73.11000112.7R156 R157 I158 R164R156-N160 PolarHBondContact NH1-ND2 3.25Å; R156-N160 VanDerWaalsContact O-CB 3.24Å; R156-N160 WeakPolarHBondContact O-CB 3.34Å; R156-N160 PolarHBondContact O-N 3.01Å; R156-N160 PolarHBondContact O-OD1 3.01Å; R157-N160 PolarHBondContact O-N 3.48Å; I158-N160 VanDerWaalsContact C-N 3.32Å; I158-N160 PolarHBondContact O-N 2.79Å; N160-R164 WeakPolarHBondContact O-CG 3.23Å
161G95.1Very high85.3Confident0 Ų067.1 Ų67.10%032%0.32CS..Hα-helixtrans-72.9-4917200000111.7R157 I158 R159 S163 R164 F358R157-G161 PolarHBondContact O-N 3.11Å; I158-G161 PolarHBondContact O-N 2.9Å; I158-G161 VanDerWaalsContact O-N 3.13Å; R159-G161 PolarHBondContact O-N 2.93Å; G161-S163 VanDerWaalsContact C-N 3.33Å; G161-S163 PolarHBondContact O-N 2.86Å; G161-R164 WeakPolarHBondContact O-CB 3.48Å; G161-R164 WeakPolarHBondContact O-CD 3.49Å; G161-R164 VanDerWaalsContact O-CG 3.25Å; G161-R164 WeakPolarHBondContact O-CG 3.24Å; G161-R164 PolarHBondContact O-N 3.15Å; G161-F358 CarbonylContact C-O 3.52Å
162A93.8Very high82.5Confident0 Ų074.4 Ų74.40%036%0.358CS..Hα-helixtrans-64.2-33.8-178.900000113.7I158 R159 R164 N361 L362 Y386I158-A162 WeakPolarHBondContact O-CB 2.96Å; I158-A162 PolarHBondContact O-N 3.48Å; R159-A162 PolarHBondContact O-N 2.72Å; A162-R164 VanDerWaalsContact C-N 3.29Å; A162-R164 PolarHBondContact O-N 3.4Å; A162-N361 PolarHBondContact O-N 2.94Å; A162-L362 HydrophobicContact CB-CB 3.74Å; A162-L362 HydrophobicContact CB-CD2 4.44Å; A162-Y386 HydrophobicContact CB-CD1 3.9Å; A162-Y386 HydrophobicContact CB-CD2 4.48Å; A162-Y386 HydrophobicContact CB-CE1 3.49Å; A162-Y386 VanDerWaalsContact CB-CE1 3.49Å; A162-Y386 HydrophobicContact CB-CE2 4.12Å; A162-Y386 HydrophobicContact CB-CG 4.37Å; A162-Y386 PolarHBondContact O-OH 3.28Å
163S90.8Very high79.9Confident67 Ų6773.8 Ų73.847%0.46937%0.367SS..THydrogen-bonded Turntrans-82.93.6179.373.20000114.2R159 G161R159-S163 VanDerWaalsContact O-CB 3.31Å; R159-S163 WeakPolarHBondContact O-CB 3.07Å; R159-S163 PolarHBondContact O-N 2.75Å; R159-S163 PolarHBondContact O-OG 3.13Å; R159-S163 VanDerWaalsContact O-OG 3.08Å; G161-S163 VanDerWaalsContact C-N 3.33Å; G161-S163 PolarHBondContact O-N 2.86Å
164R90Very high77.5Confident96 Ų9678.7 Ų78.736%0.36240%0.401SS..SBendtrans-67.4140.9179.5-68.4170.166.2-140.42.6110.2N160 G161 A162 Q166 A360N160-R164 WeakPolarHBondContact O-CG 3.23Å; G161-R164 WeakPolarHBondContact O-CB 3.48Å; G161-R164 WeakPolarHBondContact O-CD 3.49Å; G161-R164 VanDerWaalsContact O-CG 3.25Å; G161-R164 WeakPolarHBondContact O-CG 3.24Å; G161-R164 PolarHBondContact O-N 3.15Å; A162-R164 VanDerWaalsContact C-N 3.29Å; A162-R164 PolarHBondContact O-N 3.4Å; R164-Q166 PolarHBondContact O-N 2.72Å; R164-A360 HydrophobicContact CB-CB 4.26Å; R164-A360 VanDerWaalsContact O-CB 3.25Å; R164-A360 WeakPolarHBondContact O-CB 3.44Å
165P78.6Confident75Confident106 Ų10684.1 Ų84.169%0.68844%0.435SS*.  trans-65.2134.7170.827.3-32.6000109.7I167P165-I167 HydrophobicContact CB-CG1 4.45Å; P165-I167 HydrophobicContact CG-CD1 4.47Å; P165-I167 HydrophobicContact CG-CG1 4.38Å; P165-I167 PolarHBondContact O-N 3.1Å
166Q67.6Low72.1Confident87 Ų8791.9 Ų91.941%0.40748%0.476SS..  trans-77.493.5174.7-167.7176.49.100109.2R164 K168 A360 N361R164-Q166 PolarHBondContact O-N 2.72Å; Q166-K168 PolarHBondContact O-N 3.42Å; Q166-A360 HydrophobicContact CB-CB 4.32Å; Q166-N361 PolarHBondContact OE1-ND2 3.45Å
167I68.1Low69.3Low132 Ų13293.7 Ų93.768%0.67750%0.498SS*.  trans-86.896.9178.3-54.1174.8000108.6P165 I169P165-I167 HydrophobicContact CB-CG1 4.45Å; P165-I167 HydrophobicContact CG-CD1 4.47Å; P165-I167 HydrophobicContact CG-CG1 4.38Å; P165-I167 PolarHBondContact O-N 3.1Å; I167-I169 HydrophobicContact CG2-CD1 4.44Å; I167-I169 HydrophobicContact CG2-CG1 3.78Å
168K57.8Low66.4Low114 Ų11497.6 Ų97.650%0.49653%0.529SS..  trans-85.6103.7166.2-70.1-172.5178.5-173.20108.4Q166 Y170 E632Q166-K168 PolarHBondContact O-N 3.42Å; K168-Y170 HydrophobicContact CB-CE2 3.93Å; K168-Y170 WeakPolarHBondContact O-CD2 3.31Å; K168-Y170 PolarHBondContact O-N 3Å; K168-E632 IonicContact NZ-OE1 2.92Å; K168-E632 PolarHBondContact NZ-OE1 2.93Å
169I64.4Low63.4Low137 Ų137105.7 Ų105.770%0.70357%0.57SS**  trans-82.8106.8175.4-55.7179.1000108.4I167 I171I167-I169 HydrophobicContact CG2-CD1 4.44Å; I167-I169 HydrophobicContact CG2-CG1 3.78Å; I169-I171 HydrophobicContact CG2-CG1 4.09Å
170Y49.6Very low60.4Low185 Ų185109.1 Ų109.173%0.72560%0.602SS**  trans-80.4117.2168.7-62.9-88.8000108.7K168K168-Y170 HydrophobicContact CB-CE2 3.93Å; K168-Y170 WeakPolarHBondContact O-CD2 3.31Å; K168-Y170 PolarHBondContact O-N 3Å
171I59.2Low57.5Low131 Ų131110.7 Ų110.767%0.67262%0.623SS**  trans-100.593.6170.7-55.2176000106.7I169 S173I169-I171 HydrophobicContact CG2-CG1 4.09Å; I171-S173 PolarHBondContact O-N 3.47Å
172D40.1Very low54.4Low152 Ų152115.1 Ų115.181%0.81366%0.66SS**  trans-66.8103.9164.9-77.8-21.9000107.7P174D172-P174 WeakPolarHBondContact O-CD 3.37Å
173S41.6Very low51.3Low89 Ų89120.5 Ų120.562%0.62270%0.697SS**  trans-68.9123.7167.3-66.10000107.6I171 T175I171-S173 PolarHBondContact O-N 3.47Å; S173-T175 PolarHBondContact O-N 3.3Å
174P50Low48.6Very low131 Ų131127.5 Ų127.585%0.85172%0.72SS**SBendtrans-75.378.617930.4-32.5000109.7D172D172-P174 WeakPolarHBondContact O-CD 3.37Å
175T45.7Very low45.7Very low114 Ų114128.3 Ų128.370%0.69974%0.74SS**  trans-153.678.8165.88.60000109.7S173S173-T175 PolarHBondContact O-N 3.3Å
176N37.4Very low43.4Very low163 Ų163128.4 Ų128.487%0.87274%0.743SS**  trans153.581.4138.3-81.9-40.3000111
177T37.8Very low41.6Very low134 Ų134131.6 Ų131.682%0.82276%0.762SS**  trans-75.4122.415140.40000109.1
178S38.8Very low39.8Very low105 Ų105131.1 Ų131.173%0.73477%0.765SS**  trans61.7112.2154.5640000119.2
179I33.7Very low38.5Very low170 Ų170130.9 Ų130.987%0.87278%0.778SS**  -159.3118.7106.4-83.4145.7000107.3
180S33.2Very low37.7Very low119 Ų119129.5 Ų129.583%0.83278%0.778SS**  trans-77.4133.4165.1-560000109.5
181A33.7Very low36.8Very low93 Ų93129.8 Ų129.877%0.76979%0.786SS**  trans170.6122.9134.500000111.4
182A30.4Very low35.2Very low93 Ų93127.5 Ų127.577%0.76980%0.795SS**  trans32.8136.913800000121.4
183S29.6Very low34.6Very low113 Ų113123.7 Ų123.779%0.7979%0.791SS**  trans102.389.8150.8-50.20000116.4
184F32.4Very low34Very low214 Ų214127.1 Ų127.194%0.93980%0.803SS**  trans-95.8102.4142.6-84.2-82000108.3
185S31Very low33.1Very low112 Ų112126.5 Ų126.578%0.78380%0.801SS**  trans-174.4133.9139.8-89.90000112.8
186S29.8Very low32.4Very low108 Ų108126.8 Ų126.876%0.75580%0.803SS**  trans109.7132.9141.382.80000119.3
187L29.3Very low32.2Very low154 Ų154126.8 Ų126.881%0.80680%0.803SS**  trans99.889150-62.3164.4000120
188V29.9Very low31.8Very low123 Ų123130.9 Ų130.975%0.74580%0.803SS**  28.8112.7112.3-174.90000118.5
189S31.6Very low31.3Very low109 Ų109131.6 Ų131.676%0.76280%0.803SS**  trans41.8170.2130.3-52.80000121.4
190P46.2Very low31Very low108 Ų108129 Ų12970%0.70180%0.796SS**  cis-146176.29.340.3-18.4000118.7
191Q30.8Very low30.7Very low191 Ų191130.4 Ų130.489%0.89379%0.794SS**  trans75.1132.4136.6-89.3173.46.900125
192G26.6Very low30.5Very low83 Ų83131.8 Ų131.886%0.85679%0.792SS**  trans99.3131.6138.200000115.2
193G28.1Very low30.4Very low72 Ų72130.5 Ų130.574%0.74279%0.788SS**  cis167.8144.74.200000108.5
194D28.6Very low30.3Very low161 Ų161133.4 Ų133.486%0.86179%0.791SS**  trans53.7127.7154.2-76-12.9000125
195S30.2Very low30.1Very low118 Ų118132.4 Ų132.483%0.82579%0.786SS**  116.1143.7124.874.10000119.7
196T32.4Very low30Very low119 Ų119138.3 Ų138.373%0.7379%0.791SS**  trans-64.8145.4-169.648.60000116.1
197N31.5Very low29.9Very low164 Ų164138.5 Ų138.588%0.87779%0.788SS**  179162.9123.7-96.6-35.5000115.6
198R29.8Very low29.9Very low219 Ų219136.9 Ų136.983%0.82679%0.785SS**  trans-76.7-179.3-169.4-159178.7-178174.50.2114.4
199T28.4Very low30Very low120 Ų120135.8 Ų135.874%0.73678%0.783SS**  trans80.5115.1161.540.10000117.4
200V27.4Very low29.8Very low117 Ų117139.5 Ų139.571%0.70979%0.79SS**  87.8126.257.7172.10000113.7
201N27.3Very low28.9Very low148 Ų148142.8 Ų142.879%0.79180%0.796SS**  trans77.9144.6158-77.9-5.2000118.6
202V30.3Very low28.7Very low122 Ų122144.5 Ų144.574%0.73980%0.796SS**  cis-167.6155.217.8122.10000113.2
203G26.5Very low28.8Very low66 Ų66148.6 Ų148.668%0.6879%0.791SS**  trans77.3147.9142.300000120.6
204M27.9Very low28.7Very low173 Ų173148.8 Ų148.885%0.85279%0.792SS**  cis-163126.96.5-97.7137.176.100109.9
205K28.2Very low28.7Very low193 Ų193147.8 Ų147.884%0.83979%0.787SS**  60.8123107.3-75-171.8177.6-179.10120.6
206R29.2Very low28.7Very low236 Ų236149.3 Ų149.389%0.89179%0.786SS**  -174.3106.8125.2-99177.1-178.7175.81.3108.3
207T28.7Very low28.5Very low112 Ų112148.9 Ų148.969%0.68779%0.788SS**  56.9127.981.271.30000112.5
208T29.3Very low28.2Very low120 Ų120144.8 Ų144.874%0.73679%0.785SS**  cis-167.5149.435400000113.3
209S31Very low28.2Very low100 Ų100139.7 Ų139.770%0.69978%0.783SS**  trans60.6142.5134.668.80000121.5
210M28.4Very low28.1Very low188 Ų188141.7 Ų141.793%0.92679%0.789SS**  cis-162.8146.420.2-134.9164.7-175.800110.9
211E27.2Very low28.2Very low176 Ų176144.3 Ų144.382%0.82280%0.799SS**  trans-79.3161.5175.5-62.6162127.100112.7
212Y25.1Very low28.2Very low227 Ų227141 Ų14189%0.8980%0.8SS**  -157.6154.2110.6-136.2-101000113.6
213K29.3Very low28.3Very low170 Ų170144.2 Ų144.274%0.73981%0.807SS**  trans-108.8158.6-161.2-175.9-178.3-175.4177.10109.9
214G25.8Very low28.4Very low76 Ų76149.4 Ų149.478%0.78481%0.813SS**  trans175.587.7165.200000114.1
215D28.2Very low28.4Very low139 Ų139146 Ų14674%0.74381%0.806SS**  trans-70.3148.3166.5-63.7-50.1000111.3
216N30.4Very low28.6Very low150 Ų150147.7 Ų147.780%0.80281%0.807SS**  142.8140.7104.9-151.919.5000115.3
217S28.6Very low28.5Very low110 Ų110142.9 Ų142.977%0.76980%0.8SS**  trans78.3132.1146.170.50000122.5
218G25.7Very low28.5Very low79 Ų79145.7 Ų145.781%0.81481%0.811SS**  trans136.895.2138.700000117.6
219S28.8Very low28.5Very low112 Ų112149.3 Ų149.378%0.78382%0.816SS**  trans-63147.4160.4-65.10000112.5
220N27.2Very low28.3Very low162 Ų162149.5 Ų149.587%0.86682%0.824SS**  174.9143.1115.1-92.3-11000113.4
221N29.7Very low28.2Very low172 Ų172144.2 Ų144.292%0.9282%0.817SS**  trans-70159.6166.9-68.1-25.4000112.1
222G27.2Very low28.2Very low79 Ų79143.4 Ų143.481%0.81482%0.824SS**  trans-174.3129.9163.100000111.5
223E30.8Very low28.2Very low188 Ų188136.1 Ų136.188%0.87982%0.818SS**  trans-80.4170.6-165.4-63.7168.2133.900115.9
224E29.8Very low28.1Very low175 Ų175137 Ų13782%0.81882%0.824SS**  112138.8129-133.6178.2-165.100120.7
225S28.2Very low28.7Very low102 Ų102138.3 Ų138.371%0.71382%0.82SS**  trans93107155-39.10000117.5
226R31.3Very low28.5Very low228 Ų228139.7 Ų139.786%0.8683%0.827SS**  84.1125.272.6-84.3-165.9-173.71694.8116.2
227D28.5Very low28.6Very low136 Ų136141.7 Ų141.773%0.72783%0.831SS**  trans64.6119.5151.8-59.3-31.9000121.5
228D28.2Very low28.4Very low171 Ų171139.4 Ų139.491%0.91483%0.826SS**  -171.1157.8108.7-106.4-32.3000115.7
229K29.6Very low28.6Very low196 Ų196144.9 Ų144.985%0.85283%0.83SS**  trans-81.3151.4-165.7-90.4175.2170.9173.90117.6
230A27Very low28.6Very low104 Ų104146.9 Ų146.986%0.8683%0.832SS**  trans68.7125.8134.500000122.3
231G25.9Very low28.8Very low77 Ų77146.9 Ų146.979%0.79483%0.832SS**  trans16784.7159.300000116.5
232V27.7Very low28.7Very low159 Ų159141.9 Ų141.996%0.96481%0.814SS**  trans5.6129.8153.6-177.40000120
233G25Very low29Very low74 Ų74142.6 Ų142.676%0.76381%0.806SS**  trans163.995.1153.700000114.7
234E27.1Very low29.4Very low187 Ų187137.5 Ų137.587%0.87478%0.784SS**  trans-92.9169.4156.9-101.8-165.1172.400109.6
235P36.8Very low29.8Very low105 Ų105132.8 Ų132.868%0.68277%0.766SS**  cis-127.8165-13.732.1-13.9000111.9
236N24.5Very low30.2Very low167 Ų167137.4 Ų137.489%0.89377%0.768SS**  trans-149.8123.5147.1-126.84.8000110.5G238N236-G238 PolarHBondContact O-N 3.43Å
237E32.2Very low30.8Very low192 Ų192128.9 Ų128.990%0.89774%0.739SS**  trans-58.5125.4180-65.1174.1142.600110.9
238G25.1Very low30.8Very low63 Ų63128 Ų12865%0.64973%0.734SS**  trans-123.8108.6162.100000107.4N236 D240N236-G238 PolarHBondContact O-N 3.43Å; G238-D240 PolarHBondContact O-N 3.33Å
239E30.7Very low31.2Very low194 Ų194123.4 Ų123.491%0.90773%0.728SS**  trans-61.4103.7172.3-72.7177.2130.100109.7
240D27.5Very low31.1Very low154 Ų154122.3 Ų122.382%0.82473%0.726SS**  trans-85.4129.6169.3-87.9-28000111.3G238 A242G238-D240 PolarHBondContact O-N 3.33Å; D240-A242 PolarHBondContact O-N 2.83Å
241N31.4Very low31.4Very low162 Ų162125 Ų12587%0.86673%0.726SS**  trans-63.383178.7-71.9-68.9000112C243N241-C243 PolarHBondContact O-N 2.85Å
242A27.4Very low31.5Very low66 Ų66129 Ų12955%0.54573%0.729SS.*  trans-80.491.916800000110.4D240 I244D240-A242 PolarHBondContact O-N 2.83Å; A242-I244 PolarHBondContact O-N 3.06Å
243C34.5Very low31.6Very low95 Ų95125 Ų12564%0.64272%0.72SS**  trans-79.547.8175.2-160.40000112.5N241N241-C243 PolarHBondContact O-N 2.85Å
244I39Very low31.5Very low81 Ų81129.7 Ų129.742%0.41572%0.722SS.*SBendtrans-90.5129.4158.1-63.8142.7000104.7Y43 A242 R246Y43-I244 HydrophobicContact CE2-CB 4.47Å; Y43-I244 HydrophobicContact CE2-CD1 3.55Å; Y43-I244 HydrophobicContact CE2-CG1 3.82Å; Y43-I244 HydrophobicContact CE2-CG2 3.9Å; Y43-I244 WeakPolarHBondContact OH-CG2 3.39Å; A242-I244 PolarHBondContact O-N 3.06Å; I244-R246 PolarHBondContact O-N 3.23Å
245V37.8Very low31.5Very low75 Ų75128.7 Ų128.746%0.45572%0.719SS.*  trans-55.4100.7162.5177.90000104.9I247V245-I247 HydrophobicContact CG1-CG1 3.99Å; V245-I247 PolarHBondContact O-N 3.22Å
246R37.7Very low30.9Very low199 Ų199129.1 Ų129.175%0.75172%0.724SS**  trans-61.892.1168.2-76-171.8-178.6162.41.5104.2I244 N248I244-R246 PolarHBondContact O-N 3.23Å; R246-N248 PolarHBondContact O-N 2.88Å
247I42Very low30.9Very low49 Ų49128.9 Ų128.925%0.25172%0.723SS.*  trans-68.779.3166.6-63.3175.8000103.8N146 A149 V245 G249N146-I247 HydrophobicContact CB-CD1 4.35Å; N146-I247 HydrophobicContact CB-CG2 4.15Å; A149-I247 HydrophobicContact CB-CG2 3.22Å; V245-I247 HydrophobicContact CG1-CG1 3.99Å; V245-I247 PolarHBondContact O-N 3.22Å; I247-G249 PolarHBondContact O-N 3.39Å
248N30.3Very low30.6Very low117 Ų117124.3 Ų124.363%0.62672%0.718SS**  trans-63.4104.2174.8-80.60.4000106.6R246 E250R246-N248 PolarHBondContact O-N 2.88Å; N248-E250 VanDerWaalsContact C-N 3.3Å; N248-E250 PolarHBondContact O-N 3.11Å
249G35.6Very low30.5Very low76 Ų76130.9 Ų130.978%0.78473%0.732SS**  trans-8181.7162.500000108.3I247I247-G249 PolarHBondContact O-N 3.39Å
250E28.8Very low30.2Very low172 Ų172126.1 Ų126.180%0.80473%0.726SS**  trans-96.794.4162.2-74-178.5160.400107.6N248N248-E250 VanDerWaalsContact C-N 3.3Å; N248-E250 PolarHBondContact O-N 3.11Å
251D33.2Very low30Very low160 Ų160128.1 Ų128.186%0.85673%0.731SS**  trans-12964.1162.9-138.54.8000106.4
252N27.9Very low29.6Very low161 Ų161127 Ų12786%0.86173%0.73SS**  trans-9493.4166.5-89.7-6.4000107.8H254N252-H254 PolarHBondContact O-N 3.28Å
253G28.1Very low29.5Very low75 Ų75131.2 Ų131.277%0.77374%0.742SS**  trans-64.597160.100000109.1M255G253-M255 PolarHBondContact O-N 3.12Å
254H23Very low28.9Very low173 Ų173134.7 Ų134.780%0.80175%0.753SS**  trans-82.8103.6163.1-140.1-57000107.5N252 S256N252-H254 PolarHBondContact O-N 3.28Å; H254-S256 PolarHBondContact O-N 2.93Å
255M27.5Very low28.2Very low166 Ų166133.6 Ų133.682%0.81876%0.763SS**  trans-60.1126.4153.7-69.8-93.89700106.9G253G253-M255 PolarHBondContact O-N 3.12Å
256S25.6Very low27.6Very low114 Ų114139.8 Ų139.880%0.79779%0.786SS**  trans-117119.2158.855.20000107.3H254H254-S256 PolarHBondContact O-N 2.93Å
257D24.6Very low26.9Very low163 Ų163133.7 Ų133.787%0.87278%0.779SS**  trans-60.8158.6-180-83.6-44.5000113.5
258A24.2Very low26.2Very low95 Ų95139.1 Ų139.179%0.78581%0.808SS**  trans-60.4148.7177.600000114.3
259E23.7Very low25.9Very low201 Ų201137.5 Ų137.594%0.93981%0.811SS**  trans-107.3134.9147.7-78.3-170.3149.500109.8
260A24.3Very low25.5Very low95 Ų95139.5 Ų139.579%0.78581%0.813SS**  trans-81.2145-17300000112.2
261E23.2Very low25.2Very low196 Ų196138.5 Ų138.592%0.91681%0.813SS**  trans-141.5156.6145.3-83.5-153.8157.900110.9
262T23.7Very low25.8Very low139 Ų139136.2 Ų136.285%0.85381%0.807SS**  trans-94.4156.6-138.3-18.60000114.1
263I23.8Very low25.8Very low154 Ų154132.8 Ų132.879%0.7980%0.801SS**  trans-64.3136.4176.7-66.4165.7000112.9
264N23.9Very low25.7Very low167 Ų167136.4 Ų136.489%0.89380%0.798SS**  trans-173.1131.7140.4-94.4-14.6000105.9
265G24Very low25.8Very low59 Ų59135.5 Ų135.561%0.60879%0.794SS**  cis153.8139.310.100000106.4
266Q24.8Very low25.8Very low204 Ų204131.7 Ų131.795%0.95378%0.784SS**  trans74.1149.1171.8-68.2166.6-58.700118.7
267A23.6Very low25.9Very low71 Ų71133 Ų13359%0.58778%0.781SS**  cis173.7150.2-26.900000105.4
268N26.4Very low26Very low163 Ų163134.1 Ų134.187%0.87278%0.781SS**  trans76.9147.6165.2-49.4-26.8000116.2
269A24.5Very low26.1Very low84 Ų84133.1 Ų133.169%0.69478%0.78SS**  cis178.5165.1-18.600000105.3
270S27.7Very low26.2Very low117 Ų117131.2 Ų131.282%0.81878%0.776SS**  trans73.999162.154.50000120.5
271D22.5Very low26.4Very low152 Ų152131.9 Ų131.981%0.81377%0.771SS**  -39177.5129.6-89.6-22.8000115.1
272P45.2Very low26.5Very low112 Ų112131.2 Ų131.273%0.72777%0.767SS**  cis-141.4-166.3-19.132.2-9.5000113.7
273A27.4Very low26.6Very low88 Ų88129.4 Ų129.473%0.72776%0.76SS**  trans80.2144.2154.200000116.5
274E27.1Very low26.6Very low151 Ų151126.4 Ų126.471%0.70675%0.753SS**  cis-170.9159.62.8-117.4-174.3157.200106.1
275Q25.2Very low26.7Very low154 Ų154127.7 Ų127.772%0.7275%0.75SS**  trans50.4140.7140.4-63.3177.123.600119.1
276S25.5Very low26.8Very low87 Ų87131 Ų13161%0.60876%0.76SS**  cis167.8153.616.943.60000107.2
277L28.3Very low27Very low140 Ų140127.3 Ų127.373%0.73375%0.753SS**  trans66.4113.3143.3-65.2163.2000118.6
278E26.6Very low27.1Very low187 Ų187131.2 Ų131.287%0.87476%0.764SS**  82.8140.594.2-84.1-172.3170.300115.4
279G26.4Very low27.2Very low74 Ų74130.4 Ų130.476%0.76376%0.755SS**  trans103.684.5163.800000114.6
280D26.7Very low27.4Very low161 Ų161133.9 Ų133.986%0.86175%0.754SS**  84.3143.868.5-145.915000113.9
281V27.5Very low27.3Very low110 Ų110135.6 Ų135.667%0.66775%0.749SS**  trans93.9100.7163.9-167.60000120.9
282E26.6Very low27.5Very low182 Ų182135.4 Ų135.485%0.8574%0.741SS**  trans58.9139.5130-69.7-17313100125.9
283S24.2Very low26.7Very low100 Ų100138 Ų13870%0.69974%0.744SS**  trans95.296.7132165.50000119.3
284S23.8Very low26.6Very low91 Ų91137.7 Ų137.764%0.63675%0.748SS**  61.7115.9120.182.80000120.1
285K25.8Very low26.6Very low194 Ų194138.1 Ų138.184%0.84376%0.756SS**  165.5136.7103.9-90.5172.3-177.2173.40111.4
286T26.4Very low26.8Very low130 Ų130136.4 Ų136.480%0.79876%0.761SS**  trans-58.6163.8165.536.90000112.7
287P29.5Very low26.9Very low126 Ų126136 Ų13682%0.81877%0.771SS**  -140.7144.8107.533.9-18.7000115.3
288N25.5Very low26.8Very low152 Ų152135.3 Ų135.381%0.81378%0.777SS**  trans-71.4144.7164.4-89.5-29.7000111.7
289H28.1Very low26.9Very low146 Ų146133.5 Ų133.568%0.67677%0.773SS**  -176.2130.7109.2-126.9-4.7000114.8
290K28.4Very low27Very low158 Ų158136.8 Ų136.869%0.68777%0.773SS**  trans52.7144133.5-85.4177.1-174.8159.20120
291Q26.4Very low27Very low153 Ų153134.1 Ų134.172%0.71577%0.767SS**  cis-175.6157.5-1.9-162.3176.1-8.900107.8
292K27.7Very low27.1Very low148 Ų148139.7 Ų139.764%0.64378%0.777SS**  trans96.6110146-109.6173.7-180-830121.6
293E27.1Very low27.2Very low167 Ų167137.1 Ų137.178%0.7877%0.774SS**  58.4122.9129.4-76.4166.2-170.500121.7
294G26.1Very low27.3Very low80 Ų80136.8 Ų136.883%0.82578%0.777SS**  trans17695.7162.900000111.6
295D26.5Very low27.5Very low161 Ų161137.9 Ų137.986%0.86179%0.785SS**  trans-74.8132.8-179.3-173.117.1000112.3
296S30Very low27.6Very low118 Ų118140.2 Ų140.283%0.82579%0.789SS**  trans-162118.7151.2570000109.4
297G26.6Very low27.7Very low79 Ų79143.8 Ų143.881%0.81480%0.796SS**  trans-77.4156.1-16000000117.1
298S26.5Very low27.6Very low125 Ų125142.8 Ų142.887%0.87479%0.792SS**  trans-111.2116.3168.1-174.30000108.8
299L28.8Very low27.6Very low149 Ų149143.1 Ų143.178%0.7879%0.793SS**  trans-85.3140.8156.3-76.4150.7000105.8
300D27.7Very low27.6Very low143 Ų143142.9 Ų142.977%0.76580%0.801SS**  cis-155.2131.118.8-81.8-50.3000109.5
301S28.1Very low27.5Very low104 Ų104144.7 Ų144.773%0.72781%0.809SS**  trans-158.2100.315764.20000110.2
302Y28.9Very low27.6Very low228 Ų228143.9 Ų143.989%0.89482%0.815SS**  trans-160.7140.2171.2-90.4-64.7000106.2
303T29.5Very low27.6Very low128 Ų128148.4 Ų148.479%0.78583%0.828SS**  cis-161.3137.636.329.20000111.2
304A26.5Very low27.7Very low92 Ų92149 Ų14976%0.7683%0.834SS**SBendtrans-111.1134.114400000108
305S27.7Very low27.8Very low114 Ų114148.6 Ų148.680%0.79783%0.83SS**  trans42.4113.3155.3-57.80000119.9
306R28.6Very low27.8Very low244 Ų244149.1 Ų149.192%0.92183%0.833SS**  172.4112.6125.3-96.1170.5102.8129.36.6111.2
307E27.7Very low27.6Very low204 Ų204146.1 Ų146.195%0.95382%0.821SS**  trans-135.5105.8149.8-77.8-167.7163.300109.8
308S27.5Very low27.7Very low106 Ų106149.1 Ų149.174%0.74182%0.823SS**  trans-136.314614992.40000107.6
309L25.6Very low28Very low158 Ų158149.5 Ų149.583%0.82782%0.82SS**  trans72.598.3172-79.4137.7000118
310V27.3Very low27.9Very low141 Ų141149 Ų14986%0.85582%0.818SS**  trans-133.8129.8134.8-1790000111.2
311K27Very low28Very low196 Ų196150.4 Ų150.485%0.85282%0.82SS**  trans-85.1132.5179.4-178.9-178.5-175.3178.30109.3
312V28.1Very low28Very low136 Ų136150.6 Ų150.682%0.82482%0.822SS**  trans-128.3146169.7-1800000111.2
313R28.3Very low28Very low243 Ų243146.7 Ų146.792%0.91782%0.822SS**  trans-77.6163.3-157.6-64.9168.3178.7156.9-1115.1
314I29.2Very low28.1Very low179 Ų179146.8 Ų146.892%0.91882%0.822SS**  trans-102.3146.4175.8-64.6171.6000111.1
315G27.2Very low28.1Very low72 Ų72150.1 Ų150.174%0.74283%0.827SS**  trans124.5129.4162.100000112.1
316D27.8Very low28.1Very low173 Ų173152.6 Ų152.693%0.92583%0.831SS**  cis-168.6157.422.9-166.57.2000110.3
317G26.3Very low28.2Very low55 Ų55150.5 Ų150.557%0.56783%0.829SS**  trans96.488.1148.600000124.2
318T28Very low28.2Very low141 Ų141148.5 Ų148.587%0.86582%0.824SS**  trans47.7121.1136.362.90000124
319V32.1Very low28.1Very low133 Ų133150.7 Ų150.781%0.80683%0.826SS**  168.1116.31061690000111.6
320D27.7Very low28.2Very low138 Ų138153.5 Ų153.574%0.73883%0.828SS**  trans27.9134148.3-68.9-13.7000127.8
321Q28.3Very low28.2Very low173 Ų173156.3 Ų156.381%0.80883%0.828SS**  trans77.1101.6141.8-73.3178.843.700121.4
322S28.1Very low28.2Very low109 Ų109150.9 Ų150.976%0.76282%0.82SS**  167.8130.996.451.20000113.4
323T30.2Very low28.1Very low145 Ų145149.8 Ų149.889%0.8982%0.819SS**  trans64.3117.5156.7230000121.5
324V30.2Very low28.1Very low131 Ų131145 Ų14579%0.79481%0.81SS**  trans-87.6132.7-176.2172.90000111.3
325N27.6Very low28.1Very low162 Ų162145.3 Ų145.387%0.86681%0.809SS**  trans-167.897.5141.8-100.9-18.7000110.9
326N27.9Very low28Very low165 Ų165150.2 Ų150.288%0.88281%0.81SS**  trans-90.1119.3168.7-89.8-17.8000109.9
327K29.8Very low28.3Very low201 Ų201151.5 Ų151.587%0.87481%0.808SS**  trans-143.3102.5153.6-111.4-176.8-177.8179.20109.8
328L27.7Very low28.3Very low161 Ų161154.4 Ų154.484%0.84382%0.815SS**  trans-69.9131.2163.7-150.196.5000108.4
329L26.3Very low28.6Very low152 Ų152152.1 Ų152.180%0.79680%0.804SS**  trans-151.590161.2-108.3162.2000109.2K331L329-K331 PolarHBondContact O-N 3.4Å
330Y27.3Very low28.5Very low218 Ų218152 Ų15286%0.85580%0.803SS**  trans-67.2112.1156.5-102.7-93.7000107.5A332Y330-A332 PolarHBondContact O-N 2.75Å; Y330-A332 VanDerWaalsContact O-N 3.16Å
331K26.6Very low28.9Very low199 Ų199155.9 Ų155.987%0.86581%0.808SS**  trans-7496.8169.1-95.4-177.7172.5177.70108.6L329 S333L329-K331 PolarHBondContact O-N 3.4Å; K331-S333 PolarHBondContact O-N 3.1Å
332A27.7Very low29.4Very low82 Ų82154.5 Ų154.568%0.67880%0.799SS**  trans-72.2115.7151.800000107.2Y330 I334Y330-A332 PolarHBondContact O-N 2.75Å; Y330-A332 VanDerWaalsContact O-N 3.16Å; A332-I334 VanDerWaalsContact C-N 3.27Å; A332-I334 PolarHBondContact O-N 3.19Å
333S26.6Very low29.7Very low114 Ų114158 Ų15880%0.79780%0.801SS**  trans-70.388.117153.70000109K331 M335K331-S333 PolarHBondContact O-N 3.1Å; S333-M335 PolarHBondContact O-N 3.43Å
334I27.9Very low30.2Very low142 Ų142160.2 Ų160.273%0.72880%0.798SS**  trans-68.397.7163.4-61.3171.6000106.1A332 K336A332-I334 VanDerWaalsContact C-N 3.27Å; A332-I334 PolarHBondContact O-N 3.19Å; I334-K336 VanDerWaalsContact C-N 3.25Å; I334-K336 HydrophobicContact CG2-CG 4.24Å; I334-K336 PolarHBondContact O-N 2.85Å
335M28.5Very low30.9Very low186 Ų186160.4 Ų160.492%0.91679%0.79SS**  trans-66.394.3160.3-84-173.816200107.2S333 K337S333-M335 PolarHBondContact O-N 3.43Å; M335-K337 VanDerWaalsContact C-N 3.34Å; M335-K337 PolarHBondContact O-N 3.47Å
336K25.7Very low32.1Very low174 Ų174159.4 Ų159.476%0.75779%0.79SS**  trans-60.399.7163.3-84.2-178.7174.4178.30107.4I334 T338I334-K336 VanDerWaalsContact C-N 3.25Å; I334-K336 HydrophobicContact CG2-CG 4.24Å; I334-K336 PolarHBondContact O-N 2.85Å; K336-T338 PolarHBondContact O-N 2.88Å
337K34.8Very low33.6Very low201 Ų201158.9 Ų158.987%0.87479%0.787SS**  trans-72.179.2159.5-150174.9-172.9179.40106.1M335 S339M335-K337 VanDerWaalsContact C-N 3.34Å; M335-K337 PolarHBondContact O-N 3.47Å; K337-S339 PolarHBondContact O-N 3.41Å
338T26.2Very low35.8Very low116 Ų116151.8 Ų151.871%0.71276%0.757SS**  trans-64.591.6154.929.30000105K336 V340K336-T338 PolarHBondContact O-N 2.88Å; T338-V340 VanDerWaalsContact C-N 3.28Å; T338-V340 PolarHBondContact O-N 3.23Å
339S33.3Very low38.6Very low93 Ų93150.7 Ų150.765%0.6576%0.757SS**  trans-52.9105.9157.657.10000105K337 R341K337-S339 PolarHBondContact O-N 3.41Å; S339-R341 PolarHBondContact O-N 3.02Å
340V30.3Very low41.8Very low130 Ų130144.4 Ų144.479%0.78872%0.723SS**  trans-60.694.5158.9174.70000103.1T338 K342T338-V340 VanDerWaalsContact C-N 3.28Å; T338-V340 PolarHBondContact O-N 3.23Å; V340-K342 PolarHBondContact O-N 3.12Å
341R35.7Very low45Very low219 Ų219139.8 Ų139.883%0.82671%0.714SS**  trans-5997.2175.2-153.9176.7-172.6-179.62.8103.4S339 K343S339-R341 PolarHBondContact O-N 3.02Å; R341-K343 PolarHBondContact O-N 2.87Å
342K38.8Very low48.3Very low144 Ų144132.7 Ų132.763%0.62668%0.683SS**  trans-49121.6167.1-85.4176.3179.3161.20104.1V340 K344 E578V340-K342 PolarHBondContact O-N 3.12Å; K342-K344 PolarHBondContact O-N 2.7Å; K342-K344 VanDerWaalsContact O-N 3.11Å; K342-E578 IonicContact NZ-OE2 2.85Å; K342-E578 PolarHBondContact NZ-OE2 3.17Å
343K34.4Very low51.6Low183 Ų183133 Ų13380%0.79667%0.67SS**  trans-38.1119.7-179.9-169.8178.7-177.3-177.90107.6R341 H345R341-K343 PolarHBondContact O-N 2.87Å; K343-H345 PolarHBondContact O-N 2.82Å
344K40.2Very low55Low192 Ų192128.6 Ų128.684%0.83564%0.638SS**  trans-39.7112.2174.2-167.9178.9-176.1-176.90106.8K342 T346K342-K344 PolarHBondContact O-N 2.7Å; K342-K344 VanDerWaalsContact O-N 3.11Å; K344-T346 PolarHBondContact O-N 3.38Å
345H46Very low58.4Low135 Ų135122.4 Ų122.463%0.62561%0.607SS**  trans-65109.9179.6-98.5-81.8000105.5K343 D347K343-H345 PolarHBondContact O-N 2.82Å; H345-D347 PolarHBondContact O-N 3.42Å
346T52.7Low61.6Low140 Ų140113.7 Ų113.786%0.85957%0.565SS**THydrogen-bonded Turntrans-65.75.4-169.3-31.50000113.9K344K344-T346 PolarHBondContact O-N 3.38Å
347D60.1Low65Low154 Ų154108.8 Ų108.882%0.82454%0.543SS*.THydrogen-bonded Turntrans-119.9-18.3-166.2-134.317.8000114.3H345H345-D347 PolarHBondContact O-N 3.42Å
348E76.2Confident68Low52 Ų5299.2 Ų99.224%0.24350%0.502CS..  trans-105.2139.2179.4-66.6-68.2166.100110.9F350 K549 W551E348-F350 VanDerWaalsContact C-N 3.3Å; E348-F350 PolarHBondContact O-N 3.26Å; E348-K549 WeakPolarHBondContact OE1-CD 3.33Å; E348-K549 WeakPolarHBondContact OE1-CE 3.34Å; E348-K549 IonicContact OE1-NZ 2.63Å; E348-K549 PolarHBondContact OE1-NZ 3.14Å; E348-K549 IonicContact OE2-NZ 3.76Å; E348-K549 PolarHBondContact OE2-NZ 2.68Å; E348-W551 PolarHBondContact OE1-NE1 3.31Å
349T86.2Confident71.3Confident138 Ų13894 Ų9485%0.84747%0.47SS*.SBendtrans-81.3-9.1-175.452.90000113.6
350F92.8Very high74.2Confident21 Ų2190.1 Ų90.19%0.09244%0.444CS..SBendtrans-139.2161.1-173.662.8-96.8000112.5E348 H352 P540 W551 V631 F634E348-F350 VanDerWaalsContact C-N 3.3Å; E348-F350 PolarHBondContact O-N 3.26Å; F350-H352 HydrophobicContact CE2-CB 4.4Å; F350-P540 HydrophobicContact CE2-CB 4.43Å; F350-P540 HydrophobicContact CZ-CB 3.84Å; F350-W551 HydrophobicContact CE2-CH2 4.12Å; F350-W551 AromaticContact CE2-CZ2 3.91Å; F350-W551 HydrophobicContact CE2-CZ2 3.91Å; F350-W551 HydrophobicContact CZ-CH2 4.32Å; F350-W551 AromaticContact CZ-CZ2 3.82Å; F350-W551 HydrophobicContact CZ-CZ2 3.82Å; F350-V631 HydrophobicContact CB-CB 4.32Å; F350-V631 HydrophobicContact CB-CG1 4.19Å; F350-V631 WeakPolarHBondContact CB-O 3.11Å; F350-V631 HydrophobicContact CD1-CB 3.94Å; F350-V631 HydrophobicContact CD1-CG1 4.1Å; F350-V631 HydrophobicContact CD2-CB 4.43Å; F350-V631 HydrophobicContact CD2-CG1 3.7Å; F350-V631 HydrophobicContact CE1-CB 4.34Å; F350-V631 HydrophobicContact CE1-CG1 4.39Å; F350-V631 HydrophobicContact CE2-CG1 4.03Å; F350-V631 HydrophobicContact CG-CB 4Å; F350-V631 HydrophobicContact CG-CG1 3.74Å; F350-V631 HydrophobicContact CZ-CG1 4.36Å; F350-F634 HydrophobicContact CD2-CB 4.29Å; F350-F634 HydrophobicContact CE2-CB 3.82Å
351D94.5Very high77.2Confident121 Ų12186.8 Ų86.865%0.64742%0.421SS*.EExtended strand (participates in β ladder)trans-77134.8-179.6-74.2-31.6000110.6E632 E633 F634D351-E632 PolarHBondContact N-O 3.22Å; D351-E633 CarbonylContact O-C 3.57Å; D351-E633 VanDerWaalsContact O-CA 3.23Å; D351-E633 WeakPolarHBondContact O-CA 3.46Å; D351-F634 PolarHBondContact O-N 3.07Å
352H96.4Very high80.1Confident50 Ų5076.3 Ų76.323%0.23138%0.382CS..EExtended strand (participates in β ladder)trans-133134.9175.861.571.5000111.8F350 W551 F634F350-H352 HydrophobicContact CE2-CB 4.4Å; H352-W551 HydrophobicContact CB-CD2 3.99Å; H352-W551 HydrophobicContact CB-CE3 3.81Å; H352-W551 HydrophobicContact CB-CH2 4.23Å; H352-W551 HydrophobicContact CB-CZ2 4.38Å; H352-W551 HydrophobicContact CB-CZ3 3.94Å; H352-W551 AromaticContact CD2-CD1 3.81Å; H352-W551 AromaticContact CD2-CD2 3.99Å; H352-W551 AromaticContact CD2-CE2 3.97Å; H352-W551 AromaticContact CD2-CG 3.93Å; H352-W551 AromaticContact CD2-NE1 3.82Å; H352-W551 VanDerWaalsContact CE1-CB 3.49Å; H352-W551 WeakPolarHBondContact CE1-CB 3.16Å; H352-W551 AromaticContact CE1-CD1 3.84Å; H352-W551 AromaticContact CE1-CG 3.58Å; H352-W551 AromaticContact CG-CD2 3.64Å; H352-W551 AromaticContact CG-CE2 3.98Å; H352-W551 AromaticContact CG-CE3 3.92Å; H352-W551 AromaticContact CG-CG 3.82Å; H352-W551 AromaticContact ND1-CD2 3.81Å; H352-W551 AromaticContact ND1-CG 3.6Å; H352-W551 AromaticContact NE2-CD1 3.61Å; H352-W551 AromaticContact NE2-CG 3.79Å; H352-F634 VanDerWaalsContact CA-O 3.22Å; H352-F634 WeakPolarHBondContact CA-O 3.38Å
353E96.7Very high82.9Confident87 Ų8769.8 Ų69.841%0.40735%0.354SS..EExtended strand (participates in β ladder)trans-149.3162.4-177.563.8168.9-154.300114.9S355 F634 S635 F636E353-S355 VanDerWaalsContact OE1-CB 3.23Å; E353-S355 WeakPolarHBondContact OE1-CB 3.39Å; E353-S355 PolarHBondContact OE1-OG 3.21Å; E353-F634 PolarHBondContact N-O 3.12Å; E353-S635 VanDerWaalsContact O-CA 3.25Å; E353-S635 WeakPolarHBondContact O-CA 3.23Å; E353-F636 PolarHBondContact O-N 3.24Å
354I98.4Very high85.9Confident23 Ų2361.2 Ų61.212%0.11832%0.316CS..EExtended strand (participates in β ladder)trans-96.5118.4159-56.6170.2000105.2I553 Q574 L577 E578 F636 T638I354-I553 HydrophobicContact CD1-CD1 3.82Å; I354-I553 HydrophobicContact CD1-CG2 4.47Å; I354-I553 HydrophobicContact CG1-CD1 3.96Å; I354-Q574 HydrophobicContact CG2-CG 4.12Å; I354-Q574 PolarHBondContact O-NE2 2.89Å; I354-L577 HydrophobicContact CD1-CB 3.91Å; I354-L577 WeakPolarHBondContact CD1-O 3.46Å; I354-L577 HydrophobicContact CG2-CB 4.4Å; I354-E578 HydrophobicContact CD1-CG 4.18Å; I354-F636 CarbonylContact C-O 3.54Å; I354-F636 VanDerWaalsContact CA-O 3.3Å; I354-F636 WeakPolarHBondContact CA-O 3.27Å; I354-T638 HydrophobicContact CG2-CG2 3.78Å
355S97.8Very high88.7Confident12 Ų1252 Ų528%0.08428%0.277CS..EExtended strand (participates in β ladder)trans-114.9133-170.4-153.30000112E353 F357 F636 I637 T638E353-S355 VanDerWaalsContact OE1-CB 3.23Å; E353-S355 WeakPolarHBondContact OE1-CB 3.39Å; E353-S355 PolarHBondContact OE1-OG 3.21Å; S355-F357 PolarHBondContact O-N 3.25Å; S355-F357 VanDerWaalsContact O-N 3.12Å; S355-F357 PolarHBondContact OG-O 2.69Å; S355-F636 PolarHBondContact N-O 3.47Å; S355-I637 CarbonylContact O-C 3.55Å; S355-I637 VanDerWaalsContact O-CA 3.3Å; S355-I637 WeakPolarHBondContact O-CA 3.46Å; S355-T638 PolarHBondContact O-N 2.91Å; S355-T638 PolarHBondContact O-OG1 3.08Å
356A97.6Very high91.3Very high2 Ų245.7 Ų45.72%0.01725%0.248CC..SBendtrans-70.8-1.117400000114.1P570 D571 T638 Q639A356-P570 HydrophobicContact CB-CB 4.11Å; A356-D571 WeakPolarHBondContact CB-OD1 3.5Å; A356-T638 WeakPolarHBondContact CA-OG1 3.45Å; A356-Q639 WeakPolarHBondContact O-CA 3.4Å; A356-Q639 VanDerWaalsContact O-CB 3.3Å; A356-Q639 WeakPolarHBondContact O-CB 3.27Å; A356-Q639 WeakPolarHBondContact O-CG 3.4Å
357F97.1Very high93.5Very high71 Ų7139 Ų3931%0.31121%0.207SC..SBendtrans-140.4149.1-175-58.1-86.5000110.7S355S355-F357 PolarHBondContact O-N 3.25Å; S355-F357 VanDerWaalsContact O-N 3.12Å; S355-F357 PolarHBondContact OG-O 2.69Å
358F97.8Very high95.3Very high0 Ų031.7 Ų31.70%017%0.167CC..PPolyproline II helixtrans-56.6145.6158.4-81.6-93.5000109.4I158 G161 L362 L365 I637 Q639 L640 P648I158-F358 HydrophobicContact CB-CD2 4.4Å; I158-F358 HydrophobicContact CB-CE2 4.41Å; I158-F358 HydrophobicContact CD1-CE2 4.42Å; I158-F358 HydrophobicContact CD1-CZ 4.25Å; I158-F358 HydrophobicContact CG1-CD2 3.91Å; I158-F358 HydrophobicContact CG1-CE1 4.33Å; I158-F358 HydrophobicContact CG1-CE2 3.46Å; I158-F358 VanDerWaalsContact CG1-CE2 3.46Å; I158-F358 HydrophobicContact CG1-CZ 3.7Å; G161-F358 CarbonylContact C-O 3.52Å; F358-L362 HydrophobicContact CD1-CD2 4.02Å; F358-L365 HydrophobicContact CE1-CD1 4.1Å; F358-I637 HydrophobicContact CD1-CD1 3.65Å; F358-I637 HydrophobicContact CD2-CG2 3.91Å; F358-I637 HydrophobicContact CE1-CD1 3.88Å; F358-I637 HydrophobicContact CE2-CG2 4.03Å; F358-I637 HydrophobicContact CG-CD1 4.09Å; F358-I637 HydrophobicContact CG-CG2 4.27Å; F358-I637 HydrophobicContact CZ-CD1 4.49Å; F358-Q639 HydrophobicContact CD2-CB 4.12Å; F358-Q639 VanDerWaalsContact CD2-OE1 3.31Å; F358-Q639 HydrophobicContact CE2-CB 4.44Å; F358-L640 HydrophobicContact CE2-CD1 4.18Å; F358-L640 HydrophobicContact CE2-CD2 4.01Å; F358-L640 HydrophobicContact CE2-CG 3.89Å; F358-L640 HydrophobicContact CZ-CD1 4.22Å; F358-L640 HydrophobicContact CZ-CG 4.39Å; F358-P648 HydrophobicContact CE1-CB 3.81Å; F358-P648 HydrophobicContact CE1-CG 4.34Å; F358-P648 HydrophobicContact CE2-CB 4.35Å; F358-P648 HydrophobicContact CE2-CG 4.05Å; F358-P648 HydrophobicContact CZ-CB 3.49Å; F358-P648 VanDerWaalsContact CZ-CB 3.49Å; F358-P648 HydrophobicContact CZ-CG 3.51Å
359P95.4Very high96.3Very high7 Ų730.2 Ų30.25%0.04516%0.161CC..PPolyproline II helixtrans-60.6142.2-178.826.2-36.6000110.7C125 L362 A650C125-P359 WeakPolarHBondContact SG-CG 3.3Å; P359-L362 HydrophobicContact CG-CD1 4.14Å; P359-A650 HydrophobicContact CG-CB 3.73Å
360A93.2Very high96.9Very high12 Ų1224 Ų2410%0.09912%0.122CC..THydrogen-bonded Turntrans-60.9147.2170.900000110.2R164 Q166 R652R164-A360 HydrophobicContact CB-CB 4.26Å; R164-A360 VanDerWaalsContact O-CB 3.25Å; R164-A360 WeakPolarHBondContact O-CB 3.44Å; Q166-A360 HydrophobicContact CB-CB 4.32Å; A360-R652 PolarHBondContact O-NH2 3.06Å
361N92.8Very high97Very high59 Ų5924 Ų2432%0.31612%0.122SC..THydrogen-bonded Turntrans57.246.7-179-55.9-44.8000112.3C125 A162 Q166 D363 Y386C125-N361 VanDerWaalsContact CB-O 3.3Å; C125-N361 WeakPolarHBondContact CB-O 3.37Å; A162-N361 PolarHBondContact O-N 2.94Å; Q166-N361 PolarHBondContact OE1-ND2 3.45Å; N361-D363 PolarHBondContact O-N 3.18Å; N361-Y386 VanDerWaalsContact CA-OH 3.3Å; N361-Y386 WeakPolarHBondContact CA-OH 3.39Å
362L96.6Very high97Very high0 Ų018.6 Ų18.60%09%0.093CC..  trans-65.8124.8173.1-176.960.6000109.5C125 A162 F358 P359 F364 L365 Y386 F387 R417C125-L362 HydrophobicContact CB-CD1 4.44Å; A162-L362 HydrophobicContact CB-CB 3.74Å; A162-L362 HydrophobicContact CB-CD2 4.44Å; F358-L362 HydrophobicContact CD1-CD2 4.02Å; P359-L362 HydrophobicContact CG-CD1 4.14Å; L362-F364 WeakPolarHBondContact CD1-O 3.44Å; L362-L365 HydrophobicContact CD2-CB 4.32Å; L362-L365 HydrophobicContact CD2-CD1 4.16Å; L362-Y386 PolarHBondContact N-OH 3.25Å; L362-Y386 WeakPolarHBondContact O-CE1 3.31Å; L362-Y386 PolarHBondContact O-OH 2.62Å; L362-F387 HydrophobicContact CB-CZ 4.39Å; L362-F387 HydrophobicContact CD2-CZ 3.88Å; L362-F387 HydrophobicContact CG-CE1 4.47Å; L362-F387 HydrophobicContact CG-CZ 3.96Å; L362-R417 VanDerWaalsContact O-CD 3.22Å; L362-R417 WeakPolarHBondContact O-CD 3.42Å
363D97.8Very high96.8Very high7 Ų718.8 Ų18.84%0.0379%0.094CC..  trans-98.5-35.3-175.5-62.2-55.6000112.2F124 C125 N361 S416 R417 Y418F124-D363 WeakPolarHBondContact CA-OD2 3.07Å; C125-D363 PolarHBondContact N-OD2 3.04Å; C125-D363 WeakPolarHBondContact O-CA 3.08Å; C125-D363 WeakPolarHBondContact O-CB 3.3Å; C125-D363 PolarHBondContact O-N 2.93Å; N361-D363 PolarHBondContact O-N 3.18Å; D363-S416 WeakPolarHBondContact O-CA 3.42Å; D363-R417 PolarHBondContact O-N 3.42Å; D363-Y418 HydrophobicContact CB-CD2 4.2Å; D363-Y418 HydrophobicContact CB-CE2 3.94Å
364F98.8Very high96.8Very high2 Ų218.2 Ų18.21%0.0099%0.087CC..EExtended strand (participates in β ladder)trans-135.8134-175.7-50.6-73.3000110.8F124 C125 F126 G127 L362 F414 A415 S416 Y418 V447 V449 I462 F509F124-F364 HydrophobicContact CB-CE2 4.28Å; F124-F364 HydrophobicContact CD1-CE2 4.04Å; F124-F364 HydrophobicContact CD1-CZ 4.5Å; C125-F364 PolarHBondContact O-N 3.34Å; F126-F364 CarbonylContact C-O 3.49Å; F126-F364 WeakPolarHBondContact CA-O 3.22Å; F126-F364 HydrophobicContact CD1-CB 3.9Å; F126-F364 AromaticContact CD1-CD2 3.54Å; F126-F364 HydrophobicContact CD1-CD2 3.54Å; F126-F364 HydrophobicContact CD1-CE2 4.45Å; F126-F364 HydrophobicContact CD1-CG 4.04Å; F126-F364 HydrophobicContact CE1-CB 4.4Å; F126-F364 AromaticContact CE1-CD2 3.28Å; F126-F364 HydrophobicContact CE1-CD2 3.28Å; F126-F364 AromaticContact CE1-CE2 3.78Å; F126-F364 HydrophobicContact CE1-CE2 3.78Å; F126-F364 HydrophobicContact CE1-CG 4.04Å; F126-F364 HydrophobicContact CG-CD2 4.3Å; F126-F364 AromaticContact CZ-CD2 3.86Å; F126-F364 HydrophobicContact CZ-CD2 3.86Å; F126-F364 HydrophobicContact CZ-CE2 4.01Å; G127-F364 PolarHBondContact N-O 2.9Å; L362-F364 WeakPolarHBondContact CD1-O 3.44Å; F364-F414 HydrophobicContact CB-CE2 4.19Å; F364-F414 HydrophobicContact CB-CZ 4.45Å; F364-F414 HydrophobicContact CD1-CE2 4.37Å; F364-F414 AromaticContact CD1-CZ 3.83Å; F364-F414 HydrophobicContact CD1-CZ 3.83Å; F364-A415 WeakPolarHBondContact CA-O 3.44Å; F364-S416 WeakPolarHBondContact CD1-OG 3.45Å; F364-S416 WeakPolarHBondContact CE1-OG 3.47Å; F364-Y418 AromaticContact CE1-CD2 3.93Å; F364-Y418 HydrophobicContact CE1-CD2 3.93Å; F364-Y418 HydrophobicContact CE1-CG 4.4Å; F364-Y418 HydrophobicContact CE2-CD2 4.37Å; F364-Y418 AromaticContact CZ-CD2 3.58Å; F364-Y418 HydrophobicContact CZ-CD2 3.58Å; F364-Y418 HydrophobicContact CZ-CE2 4.3Å; F364-Y418 HydrophobicContact CZ-CG 4.21Å; F364-V447 HydrophobicContact CE1-CB 4.21Å; F364-V447 HydrophobicContact CE1-CG1 4.12Å; F364-V447 HydrophobicContact CE1-CG2 3.78Å; F364-V447 HydrophobicContact CZ-CG2 3.96Å; F364-V449 HydrophobicContact CZ-CG1 3.95Å; F364-I462 HydrophobicContact CB-CD1 3.86Å; F364-I462 HydrophobicContact CD1-CD1 3.31Å; F364-I462 HydrophobicContact CD2-CD1 3.9Å; F364-I462 HydrophobicContact CE1-CD1 3.74Å; F364-I462 HydrophobicContact CE2-CD1 4.28Å; F364-I462 HydrophobicContact CG-CD1 3.39Å; F364-I462 HydrophobicContact CZ-CD1 4.22Å; F364-F509 HydrophobicContact CD2-CZ 4.47Å; F364-F509 HydrophobicContact CE2-CE1 4.16Å; F364-F509 HydrophobicContact CE2-CE2 4.22Å; F364-F509 AromaticContact CE2-CZ 3.53Å; F364-F509 HydrophobicContact CE2-CZ 3.53Å; F364-F509 HydrophobicContact CZ-CE1 4.42Å; F364-F509 HydrophobicContact CZ-CE2 4.43Å; F364-F509 AromaticContact CZ-CZ 3.62Å; F364-F509 HydrophobicContact CZ-CZ 3.62Å
365L98.9Very high96.7Very high0 Ų017.1 Ų17.10%08%0.082CC..EExtended strand (participates in β ladder)trans-131.3126.5179.1177.672.1000110.3G127 I158 F358 L362 L367 L383 F387 F414 A415G127-L365 CarbonylContact O-C 3.48Å; G127-L365 WeakPolarHBondContact O-CA 3.36Å; I158-L365 HydrophobicContact CD1-CD2 4.2Å; I158-L365 HydrophobicContact CG2-CD2 3.75Å; F358-L365 HydrophobicContact CE1-CD1 4.1Å; L362-L365 HydrophobicContact CD2-CB 4.32Å; L362-L365 HydrophobicContact CD2-CD1 4.16Å; L365-L367 HydrophobicContact CD1-CD2 3.78Å; L365-L367 HydrophobicContact CD2-CD1 4.16Å; L365-L367 HydrophobicContact CD2-CD2 4.03Å; L365-L367 HydrophobicContact CD2-CG 4.12Å; L365-L367 HydrophobicContact CG-CD2 3.83Å; L365-L367 HydrophobicContact CG-CG 4.04Å; L365-L383 HydrophobicContact CD2-CD1 4.22Å; L365-L383 HydrophobicContact CD2-CD2 4.01Å; L365-F387 HydrophobicContact CB-CE1 4.5Å; L365-F387 HydrophobicContact CB-CE2 4.24Å; L365-F387 HydrophobicContact CB-CZ 3.9Å; L365-F387 HydrophobicContact CD2-CE2 4.01Å; L365-F387 HydrophobicContact CD2-CZ 4.44Å; L365-F414 CarbonylContact O-C 3.36Å; L365-F414 WeakPolarHBondContact O-CA 3.19Å; L365-A415 HydrophobicContact CB-CB 4.31Å; L365-A415 PolarHBondContact N-O 3.25Å; L365-A415 PolarHBondContact O-N 3.18Å
366C98.9Very high96.7Very high2 Ų216.8 Ų16.81%0.0148%0.08CC..EExtended strand (participates in β ladder)trans-113.9121.8176.8-65.50000109.6G127 S128 A129 C464 C513G127-C366 PolarHBondContact O-N 3.18Å; S128-C366 CarbonylContact C-O 3.55Å; S128-C366 WeakPolarHBondContact CA-O 3.46Å; S128-C366 PolarHBondContact OG-O 3.26Å; A129-C366 PolarHBondContact N-O 2.78Å; C366-C464 HydrophobicContact CB-CB 3.89Å; C366-C513 WeakPolarHBondContact CB-SG 3.29Å; C366-C513 PolarHBondContact SG-SG 3.42Å
367L98.9Very high96.6Very high0 Ų019.7 Ų19.70%09%0.093CC..EExtended strand (participates in β ladder)trans-116.2142.1-180-55.6-178.4000111A129 V131 I158 L365 V370 L379 L383 L412 L413A129-L367 HydrophobicContact CB-CD2 3.75Å; A129-L367 CarbonylContact O-C 3.56Å; A129-L367 VanDerWaalsContact O-CA 3.27Å; A129-L367 WeakPolarHBondContact O-CA 3.4Å; V131-L367 HydrophobicContact CG1-CD2 4.05Å; I158-L367 HydrophobicContact CD1-CD2 4.43Å; L365-L367 HydrophobicContact CD1-CD2 3.78Å; L365-L367 HydrophobicContact CD2-CD1 4.16Å; L365-L367 HydrophobicContact CD2-CD2 4.03Å; L365-L367 HydrophobicContact CD2-CG 4.12Å; L365-L367 HydrophobicContact CG-CD2 3.83Å; L365-L367 HydrophobicContact CG-CG 4.04Å; L367-V370 HydrophobicContact CB-CG2 3.79Å; L367-V370 HydrophobicContact CD1-CG2 4.49Å; L367-L379 HydrophobicContact CD1-CD2 3.67Å; L367-L379 HydrophobicContact CD1-CG 4.44Å; L367-L383 HydrophobicContact CD1-CD1 4.22Å; L367-L412 WeakPolarHBondContact O-CA 3.22Å; L367-L413 HydrophobicContact CB-CB 4.26Å; L367-L413 HydrophobicContact CD1-CD2 4.06Å; L367-L413 HydrophobicContact CG-CD2 4.43Å; L367-L413 PolarHBondContact N-O 3.48Å; L367-L413 PolarHBondContact O-N 3.2Å
368Q98.6Very high96.7Very high0 Ų019.2 Ų19.20%09%0.091CC..EExtended strand (participates in β ladder)trans-113158.4173.1-56.178.342.600110.5S128 A129 N130 V131 V370 G411 L412 C464 H466 D515S128-Q368 PolarHBondContact OG-NE2 3.19Å; S128-Q368 VanDerWaalsContact OG-NE2 3.07Å; S128-Q368 PolarHBondContact OG-OE1 2.92Å; A129-Q368 PolarHBondContact O-N 2.91Å; A129-Q368 PolarHBondContact O-OE1 2.91Å; N130-Q368 HydrophobicContact CB-CB 4.19Å; V131-Q368 VanDerWaalsContact CG2-O 3.28Å; V131-Q368 WeakPolarHBondContact CG2-O 3.42Å; V131-Q368 PolarHBondContact N-O 2.82Å; Q368-V370 VanDerWaalsContact C-N 3.33Å; Q368-V370 PolarHBondContact O-N 2.86Å; Q368-G411 CarbonylContact C-O 3.59Å; Q368-G411 WeakPolarHBondContact CA-O 3.46Å; Q368-L412 HydrophobicContact CG-CD2 4.01Å; Q368-C464 PolarHBondContact NE2-SG 3.23Å; Q368-H466 HydrophobicContact CG-CB 4.26Å; Q368-D515 HydrophobicContact CG-CB 4.31Å
369E97.3Very high96.7Very high21 Ų2119.2 Ų19.210%0.0989%0.091CC..  trans58.832.6-178.5-56.3-165.3-173.800116.5N130 C132 L133 L134 F371 G411 H466N130-E369 VanDerWaalsContact ND2-CD 3.28Å; N130-E369 WeakPolarHBondContact ND2-CG 3.23Å; N130-E369 PolarHBondContact ND2-OE1 3.29Å; N130-E369 VanDerWaalsContact OD1-CB 3.26Å; N130-E369 WeakPolarHBondContact OD1-CB 3.16Å; N130-E369 WeakPolarHBondContact OD1-CG 3.08Å; C132-E369 WeakPolarHBondContact CA-OE2 3.36Å; C132-E369 PolarHBondContact SG-OE2 2.87Å; L133-E369 CarbonylContact C-O 3.6Å; L133-E369 WeakPolarHBondContact CA-O 3.33Å; L133-E369 WeakPolarHBondContact CB-O 3.43Å; L133-E369 PolarHBondContact N-O 2.83Å; L134-E369 WeakPolarHBondContact CD1-OE2 3.16Å; E369-F371 HydrophobicContact CB-CD2 3.92Å; E369-F371 HydrophobicContact CB-CE2 3.67Å; E369-F371 HydrophobicContact CG-CD2 4.36Å; E369-F371 HydrophobicContact CG-CE2 3.61Å; E369-F371 HydrophobicContact CG-CZ 4.23Å; E369-F371 PolarHBondContact O-N 2.85Å; E369-G411 PolarHBondContact N-O 3.42Å; E369-H466 IonicContact OE1-CE1 2.93Å; E369-H466 PolarHBondContact OE1-CE1 3.26Å
370V97.9Very high96.8Very high6 Ų620 Ų204%0.0369%0.093CC..  trans-81.860.7168.6-164.70000110.6V131 L133 L367 Q368 A376 L379 G411 L413V131-V370 HydrophobicContact CG2-CG2 3.69Å; L133-V370 HydrophobicContact CD1-CG1 4.38Å; L367-V370 HydrophobicContact CB-CG2 3.79Å; L367-V370 HydrophobicContact CD1-CG2 4.49Å; Q368-V370 VanDerWaalsContact C-N 3.33Å; Q368-V370 PolarHBondContact O-N 2.86Å; V370-A376 HydrophobicContact CG1-CB 3.57Å; V370-L379 HydrophobicContact CG1-CD2 4.09Å; V370-L379 HydrophobicContact CG2-CD2 4.22Å; V370-G411 PolarHBondContact N-O 3.22Å; V370-L413 HydrophobicContact CB-CB 4.39Å; V370-L413 HydrophobicContact CG1-CD1 4.25Å; V370-L413 HydrophobicContact CG2-CB 3.99Å
371F95.1Very high97Very high21 Ų2124.3 Ų24.39%0.09211%0.112CC..  trans-84.2-44.3-170.3-65-61.3000114.5L133 L134 E369 K373 V408 N409 A438L133-F371 PolarHBondContact O-N 2.77Å; L134-F371 HydrophobicContact CD2-CD2 3.72Å; L134-F371 HydrophobicContact CD2-CE2 3.93Å; L134-F371 HydrophobicContact CG-CD2 3.89Å; L134-F371 HydrophobicContact CG-CE2 4.43Å; E369-F371 HydrophobicContact CB-CD2 3.92Å; E369-F371 HydrophobicContact CB-CE2 3.67Å; E369-F371 HydrophobicContact CG-CD2 4.36Å; E369-F371 HydrophobicContact CG-CE2 3.61Å; E369-F371 HydrophobicContact CG-CZ 4.23Å; E369-F371 PolarHBondContact O-N 2.85Å; F371-K373 PolarHBondContact O-N 3.02Å; F371-V408 HydrophobicContact CB-CG1 3.89Å; F371-V408 HydrophobicContact CD1-CG1 3.41Å; F371-V408 VanDerWaalsContact CD1-CG1 3.41Å; F371-V408 HydrophobicContact CE1-CG1 4.11Å; F371-V408 HydrophobicContact CG-CG1 3.86Å; F371-N409 WeakPolarHBondContact CD1-OD1 3.42Å; F371-N409 WeakPolarHBondContact CE1-O 3.23Å; F371-A438 HydrophobicContact CE1-CB 4.49Å
372D95.2Very high97.2Very high8 Ų823.4 Ų23.44%0.04311%0.106CC..  trans-70.4116.5179.3179-71.9000109.8Y28 L133 T147 Q148 R374 A375 A376Y28-D372 PolarHBondContact OH-OD2 3.24Å; L133-D372 PolarHBondContact O-N 3Å; T147-D372 HydrophobicContact CG2-CB 4.17Å; Q148-D372 VanDerWaalsContact NE2-CG 3.34Å; Q148-D372 PolarHBondContact NE2-OD1 3.29Å; D372-R374 VanDerWaalsContact C-N 3.27Å; D372-R374 PolarHBondContact O-N 2.84Å; D372-R374 WeakPolarHBondContact OD1-CA 3.21Å; D372-R374 WeakPolarHBondContact OD1-CB 3.46Å; D372-R374 PolarHBondContact OD1-N 2.84Å; D372-R374 IonicContact OD1-NE 2.75Å; D372-R374 IonicContact OD2-CZ 3.7Å; D372-R374 IonicContact OD2-NE 3.92Å; D372-R374 IonicContact OD2-NH2 3.43Å; D372-R374 PolarHBondContact OD2-NH2 2.99Å; D372-A375 HydrophobicContact CB-CB 3.94Å; D372-A375 WeakPolarHBondContact O-CB 3.26Å; D372-A375 PolarHBondContact O-N 3.2Å; D372-A375 PolarHBondContact OD1-N 3.35Å; D372-A376 WeakPolarHBondContact O-CB 3.27Å; D372-A376 PolarHBondContact O-N 2.88Å
373K92.9Very high97.2Very high55 Ų5523.4 Ų23.424%0.23911%0.106CC..Hα-helixtrans-59-34.6-175.1-64.3-176.5-178.9-104.20113.7F371 A376 E377 D393 Y397F371-K373 PolarHBondContact O-N 3.02Å; K373-A376 WeakPolarHBondContact O-CB 3.24Å; K373-A376 PolarHBondContact O-N 3.44Å; K373-E377 WeakPolarHBondContact O-CG 3.27Å; K373-E377 PolarHBondContact O-N 3.47Å; K373-D393 IonicContact NZ-OD1 3.87Å; K373-D393 PolarHBondContact NZ-OD1 2.8Å; K373-D393 IonicContact NZ-OD2 3.08Å; K373-D393 PolarHBondContact NZ-OD2 3.43Å; K373-Y397 WeakPolarHBondContact CE-OH 3.44Å; K373-Y397 PolarHBondContact NZ-OH 2.82Å
374R95.1Very high97.2Very high74 Ų7424 Ų2428%0.27911%0.108SC..Hα-helixtrans-76.6-35.6-178.4-60.1167.9-65.5169.8-1110.9F25 D372 K378F25-R374 VanDerWaalsContact CE2-NH1 3.31Å; D372-R374 VanDerWaalsContact C-N 3.27Å; D372-R374 PolarHBondContact O-N 2.84Å; D372-R374 WeakPolarHBondContact OD1-CA 3.21Å; D372-R374 WeakPolarHBondContact OD1-CB 3.46Å; D372-R374 PolarHBondContact OD1-N 2.84Å; D372-R374 IonicContact OD1-NE 2.75Å; D372-R374 IonicContact OD2-CZ 3.7Å; D372-R374 IonicContact OD2-NE 3.92Å; D372-R374 IonicContact OD2-NH2 3.43Å; D372-R374 PolarHBondContact OD2-NH2 2.99Å; R374-K378 WeakPolarHBondContact O-CG 3.43Å; R374-K378 PolarHBondContact O-N 2.96Å; R374-K378 VanDerWaalsContact O-N 3.15Å
375A97.2Very high96.9Very high0 Ų030.1 Ų30.10%014%0.137CC..Hα-helixtrans-64.8-43.1170.300000110.6L133 T147 A151 D372 E377 K378 L379L133-A375 HydrophobicContact CB-CB 4.39Å; L133-A375 HydrophobicContact CD1-CB 4.46Å; T147-A375 HydrophobicContact CG2-CB 3.71Å; A151-A375 HydrophobicContact CB-CB 3.77Å; A151-A375 VanDerWaalsContact CB-O 3.31Å; A151-A375 WeakPolarHBondContact CB-O 3.44Å; D372-A375 HydrophobicContact CB-CB 3.94Å; D372-A375 WeakPolarHBondContact O-CB 3.26Å; D372-A375 PolarHBondContact O-N 3.2Å; D372-A375 PolarHBondContact OD1-N 3.35Å; A375-E377 PolarHBondContact O-N 3.03Å; A375-K378 PolarHBondContact O-N 3.5Å; A375-L379 WeakPolarHBondContact O-CB 3.48Å; A375-L379 PolarHBondContact O-N 2.79Å
376A97.4Very high96.7Very high5 Ų532 Ų324%0.04114%0.144CC..Hα-helixtrans-57.5-45.1175.400000112.4V370 D372 K373 L379 K380V370-A376 HydrophobicContact CG1-CB 3.57Å; D372-A376 WeakPolarHBondContact O-CB 3.27Å; D372-A376 PolarHBondContact O-N 2.88Å; K373-A376 WeakPolarHBondContact O-CB 3.24Å; K373-A376 PolarHBondContact O-N 3.44Å; A376-L379 PolarHBondContact O-N 2.82Å; A376-K380 VanDerWaalsContact O-CB 3.31Å; A376-K380 WeakPolarHBondContact O-CB 3.49Å; A376-K380 PolarHBondContact O-N 2.81Å
377E96.5Very high96.6Very high63 Ų6332 Ų3229%0.29414%0.143SC..Hα-helixtrans-61.3-48.4175.8-73.4-66158.100111.9K373 A375 L379 K380 E381 Y392K373-E377 WeakPolarHBondContact O-CG 3.27Å; K373-E377 PolarHBondContact O-N 3.47Å; A375-E377 PolarHBondContact O-N 3.03Å; E377-L379 VanDerWaalsContact C-N 3.32Å; E377-L379 PolarHBondContact O-N 2.8Å; E377-K380 WeakPolarHBondContact O-CB 3.36Å; E377-K380 PolarHBondContact O-N 2.94Å; E377-K380 IonicContact OE1-NZ 2.75Å; E377-K380 PolarHBondContact OE1-NZ 3.07Å; E377-K380 WeakPolarHBondContact OE2-CE 3.35Å; E377-K380 IonicContact OE2-NZ 3.68Å; E377-K380 PolarHBondContact OE2-NZ 2.82Å; E377-E381 WeakPolarHBondContact O-CG 3.33Å; E377-E381 PolarHBondContact O-N 2.68Å; E377-Y392 WeakPolarHBondContact OE1-CE2 3.23Å; E377-Y392 VanDerWaalsContact OE1-CZ 3.24Å; E377-Y392 PolarHBondContact OE1-OH 3.14Å
378K97.9Very high96.5Very high62 Ų6234.9 Ų34.927%0.2716%0.157SC..Hα-helixtrans-61-39.1176.7-75.1171.1-180170.30112.9Q148 A151 K152 R374 A375 Q382Q148-K378 HydrophobicContact CB-CD 4.39Å; A151-K378 HydrophobicContact CB-CB 4.43Å; K152-K378 HydrophobicContact CD-CD 4.42Å; K152-K378 HydrophobicContact CG-CB 3.85Å; K152-K378 HydrophobicContact CG-CD 4.14Å; K152-K378 HydrophobicContact CG-CG 4.19Å; R374-K378 WeakPolarHBondContact O-CG 3.43Å; R374-K378 PolarHBondContact O-N 2.96Å; R374-K378 VanDerWaalsContact O-N 3.15Å; A375-K378 PolarHBondContact O-N 3.5Å; K378-Q382 WeakPolarHBondContact O-CG 3.43Å; K378-Q382 PolarHBondContact O-N 3.25Å
379L98.5Very high96.4Very high0 Ų035.5 Ų35.50%016%0.159CC..Hα-helixtrans-65.8-48.6176176.360.8000110.5L133 A151 I154 G155 L367 V370 A375 A376 E377 E381 Q382 L383 L413L133-L379 HydrophobicContact CD1-CD2 3.75Å; A151-L379 HydrophobicContact CB-CB 4.3Å; I154-L379 HydrophobicContact CG2-CD1 4.14Å; G155-L379 VanDerWaalsContact CA-CD1 3.49Å; L367-L379 HydrophobicContact CD1-CD2 3.67Å; L367-L379 HydrophobicContact CD1-CG 4.44Å; V370-L379 HydrophobicContact CG1-CD2 4.09Å; V370-L379 HydrophobicContact CG2-CD2 4.22Å; A375-L379 WeakPolarHBondContact O-CB 3.48Å; A375-L379 PolarHBondContact O-N 2.79Å; A376-L379 PolarHBondContact O-N 2.82Å; E377-L379 VanDerWaalsContact C-N 3.32Å; E377-L379 PolarHBondContact O-N 2.8Å; L379-E381 VanDerWaalsContact C-N 3.35Å; L379-E381 PolarHBondContact O-N 3.47Å; L379-Q382 PolarHBondContact O-N 2.91Å; L379-Q382 VanDerWaalsContact O-N 3.12Å; L379-L383 HydrophobicContact CD1-CD1 4.05Å; L379-L383 HydrophobicContact CD1-CG 4.11Å; L379-L383 HydrophobicContact CG-CD1 3.94Å; L379-L383 HydrophobicContact CG-CG 4.38Å; L379-L383 WeakPolarHBondContact O-CG 3.21Å; L379-L383 PolarHBondContact O-N 3.42Å; L379-L413 HydrophobicContact CD2-CD1 4.36Å
380K97.6Very high96.5Very high22 Ų2234.5 Ų34.510%0.09616%0.155CC..Hα-helixtrans-55.8-47.3176.6179.5-167.568.9-179.30111.5A376 E377 Q382 L383 H384 I390 Y392A376-K380 VanDerWaalsContact O-CB 3.31Å; A376-K380 WeakPolarHBondContact O-CB 3.49Å; A376-K380 PolarHBondContact O-N 2.81Å; E377-K380 WeakPolarHBondContact O-CB 3.36Å; E377-K380 PolarHBondContact O-N 2.94Å; E377-K380 IonicContact OE1-NZ 2.75Å; E377-K380 PolarHBondContact OE1-NZ 3.07Å; E377-K380 WeakPolarHBondContact OE2-CE 3.35Å; E377-K380 IonicContact OE2-NZ 3.68Å; E377-K380 PolarHBondContact OE2-NZ 2.82Å; K380-Q382 VanDerWaalsContact C-N 3.29Å; K380-Q382 PolarHBondContact O-N 2.88Å; K380-L383 PolarHBondContact O-N 3.14Å; K380-H384 WeakPolarHBondContact O-CB 3.47Å; K380-H384 PolarHBondContact O-N 3.43Å; K380-I390 HydrophobicContact CG-CD1 3.97Å; K380-I390 HydrophobicContact CG-CG2 4.16Å; K380-Y392 HydrophobicContact CD-CD1 3.81Å; K380-Y392 HydrophobicContact CD-CE1 3.66Å; K380-Y392 HydrophobicContact CD-CE2 4.44Å; K380-Y392 HydrophobicContact CD-CG 4.25Å; K380-Y392 PolarHBondContact NZ-OH 3.48Å
381E96.5Very high96.5Very high104 Ų10434.2 Ų34.249%0.48615%0.153SC..Hα-helixtrans-55.5-44175.9-74170.717900111.8E377 L379 H385E377-E381 WeakPolarHBondContact O-CG 3.33Å; E377-E381 PolarHBondContact O-N 2.68Å; L379-E381 VanDerWaalsContact C-N 3.35Å; L379-E381 PolarHBondContact O-N 3.47Å; E381-H385 PolarHBondContact O-CD2 3.44Å; E381-H385 VanDerWaalsContact O-CD2 3.26Å
382Q97.2Very high96.6Very high40 Ų4034.2 Ų34.219%0.18715%0.153CC..Hα-helixtrans-68.6-36.9178-69.4-57.7-51.400113.2K378 L379 K380 H385K378-Q382 WeakPolarHBondContact O-CG 3.43Å; K378-Q382 PolarHBondContact O-N 3.25Å; L379-Q382 PolarHBondContact O-N 2.91Å; L379-Q382 VanDerWaalsContact O-N 3.12Å; K380-Q382 VanDerWaalsContact C-N 3.29Å; K380-Q382 PolarHBondContact O-N 2.88Å; Q382-H385 PolarHBondContact O-CD2 3.2Å
383L97.7Very high96.6Very high0 Ų034.8 Ų34.80%016%0.156CC..Hα-helixtrans-72.9-33.4179.7-69178.1000112.8I158 L365 L367 L379 K380 H385 Y386 F387 I390 L413I158-L383 HydrophobicContact CB-CD2 4.16Å; I158-L383 HydrophobicContact CD1-CD2 4.47Å; I158-L383 HydrophobicContact CG2-CD2 3.81Å; L365-L383 HydrophobicContact CD2-CD1 4.22Å; L365-L383 HydrophobicContact CD2-CD2 4.01Å; L367-L383 HydrophobicContact CD1-CD1 4.22Å; L379-L383 HydrophobicContact CD1-CD1 4.05Å; L379-L383 HydrophobicContact CD1-CG 4.11Å; L379-L383 HydrophobicContact CG-CD1 3.94Å; L379-L383 HydrophobicContact CG-CG 4.38Å; L379-L383 WeakPolarHBondContact O-CG 3.21Å; L379-L383 PolarHBondContact O-N 3.42Å; K380-L383 PolarHBondContact O-N 3.14Å; L383-H385 PolarHBondContact O-N 3.34Å; L383-H385 VanDerWaalsContact O-N 3.12Å; L383-Y386 PolarHBondContact O-N 2.75Å; L383-F387 HydrophobicContact CB-CD2 4.26Å; L383-F387 HydrophobicContact CD2-CD2 4.23Å; L383-F387 HydrophobicContact CD2-CE2 4.23Å; L383-F387 PolarHBondContact O-N 2.93Å; L383-I390 HydrophobicContact CB-CD1 3.79Å; L383-L413 HydrophobicContact CD1-CD2 3.99Å
384H96.2Very high96.7Very high20 Ų2032.2 Ų32.29%0.09314%0.144CC..Hα-helixtrans-60.2-21.1178.4-99.6-45.6000113.8S98 L100 K380 Y386 F387 I390S98-H384 PolarHBondContact OG-NE2 3.32Å; L100-H384 HydrophobicContact CD1-CB 4.27Å; K380-H384 WeakPolarHBondContact O-CB 3.47Å; K380-H384 PolarHBondContact O-N 3.43Å; H384-Y386 PolarHBondContact O-N 2.93Å; H384-Y386 VanDerWaalsContact O-N 3.09Å; H384-F387 WeakPolarHBondContact CA-O 3.46Å; H384-F387 PolarHBondContact ND1-O 3.46Å; H384-I390 HydrophobicContact CB-CD1 4.49Å
385H94.1Very high96.5Very high130 Ų13028.7 Ų28.760%0.60213%0.131SC*.THydrogen-bonded Turntrans-65.2-7.6171.3-69.9-74.7000114.1R159 E381 Q382 L383R159-H385 VanDerWaalsContact CD-CB 3.41Å; R159-H385 HydrophobicContact CG-CB 4.43Å; R159-H385 PolarHBondContact NH1-CD2 2.83Å; E381-H385 PolarHBondContact O-CD2 3.44Å; E381-H385 VanDerWaalsContact O-CD2 3.26Å; Q382-H385 PolarHBondContact O-CD2 3.2Å; L383-H385 PolarHBondContact O-N 3.34Å; L383-H385 VanDerWaalsContact O-N 3.12Å
386Y95Very high95.9Very high39 Ų3930.4 Ų30.415%0.15314%0.142CC..THydrogen-bonded Turntrans-138.5-40.4-180180-94.7000113.5A162 N361 L362 L383 H384 R417A162-Y386 HydrophobicContact CB-CD1 3.9Å; A162-Y386 HydrophobicContact CB-CD2 4.48Å; A162-Y386 HydrophobicContact CB-CE1 3.49Å; A162-Y386 VanDerWaalsContact CB-CE1 3.49Å; A162-Y386 HydrophobicContact CB-CE2 4.12Å; A162-Y386 HydrophobicContact CB-CG 4.37Å; A162-Y386 PolarHBondContact O-OH 3.28Å; N361-Y386 VanDerWaalsContact CA-OH 3.3Å; N361-Y386 WeakPolarHBondContact CA-OH 3.39Å; L362-Y386 PolarHBondContact N-OH 3.25Å; L362-Y386 WeakPolarHBondContact O-CE1 3.31Å; L362-Y386 PolarHBondContact O-OH 2.62Å; L383-Y386 PolarHBondContact O-N 2.75Å; H384-Y386 PolarHBondContact O-N 2.93Å; H384-Y386 VanDerWaalsContact O-N 3.09Å; Y386-R417 HydrophobicContact CE1-CG 4.05Å
387F96.3Very high94.8Very high1 Ų130.6 Ų30.60%0.00414%0.141CC..  trans-96122176.5-63.8-72.9000110.3I158 L362 L365 L383 H384 I390 A415 R417I158-F387 HydrophobicContact CG2-CE2 4.41Å; L362-F387 HydrophobicContact CB-CZ 4.39Å; L362-F387 HydrophobicContact CD2-CZ 3.88Å; L362-F387 HydrophobicContact CG-CE1 4.47Å; L362-F387 HydrophobicContact CG-CZ 3.96Å; L365-F387 HydrophobicContact CB-CE1 4.5Å; L365-F387 HydrophobicContact CB-CE2 4.24Å; L365-F387 HydrophobicContact CB-CZ 3.9Å; L365-F387 HydrophobicContact CD2-CE2 4.01Å; L365-F387 HydrophobicContact CD2-CZ 4.44Å; L383-F387 HydrophobicContact CB-CD2 4.26Å; L383-F387 HydrophobicContact CD2-CD2 4.23Å; L383-F387 HydrophobicContact CD2-CE2 4.23Å; L383-F387 PolarHBondContact O-N 2.93Å; H384-F387 WeakPolarHBondContact CA-O 3.46Å; H384-F387 PolarHBondContact ND1-O 3.46Å; F387-I390 HydrophobicContact CB-CG1 4.36Å; F387-A415 HydrophobicContact CB-CB 3.86Å; F387-A415 HydrophobicContact CD1-CB 4.16Å; F387-A415 HydrophobicContact CD2-CB 3.75Å; F387-A415 HydrophobicContact CE2-CB 4.3Å; F387-A415 HydrophobicContact CG-CB 3.66Å; F387-R417 HydrophobicContact CD1-CG 3.78Å; F387-R417 HydrophobicContact CE1-CG 4.06Å
388E95.5Very high93.2Very high61 Ų6128.1 Ų28.129%0.28513%0.131SC..SBendtrans-75.2-32179.2-173.6-172.6162.300112.2R99 L100 S416R99-E388 WeakPolarHBondContact CA-O 3.43Å; R99-E388 HydrophobicContact CG-CG 4.23Å; R99-E388 IonicContact CZ-OE1 3.79Å; R99-E388 VanDerWaalsContact CZ-OE1 3.28Å; R99-E388 IonicContact NE-OE1 2.64Å; R99-E388 PolarHBondContact NE-OE1 3.34Å; R99-E388 IonicContact NH2-OE1 3.76Å; R99-E388 PolarHBondContact NH2-OE1 2.86Å; L100-E388 HydrophobicContact CB-CG 4.43Å; L100-E388 PolarHBondContact N-O 3.08Å; E388-S416 PolarHBondContact N-O 3.47Å
389Y97.6Very high91.2Very high13 Ų1329 Ų295%0.05114%0.144CC..EExtended strand (participates in β ladder)trans-116.8116.5-170.7-53.6-79.6000110.8Y97 R99 A415 S416 Y418 P419Y97-Y389 HydrophobicContact CE2-CD1 4.07Å; Y97-Y389 WeakPolarHBondContact OH-CD1 3.33Å; R99-Y389 HydrophobicContact CG-CD1 4.1Å; R99-Y389 HydrophobicContact CG-CE1 3.99Å; R99-Y389 PolarHBondContact NH2-OH 3.07Å; Y389-A415 CarbonylContact O-C 3.52Å; Y389-A415 WeakPolarHBondContact O-CA 3.37Å; Y389-S416 PolarHBondContact N-O 2.85Å; Y389-S416 PolarHBondContact O-N 2.78Å; Y389-Y418 WeakPolarHBondContact CD2-O 3.49Å; Y389-P419 HydrophobicContact CE1-CB 4.24Å; Y389-P419 HydrophobicContact CE2-CB 4.36Å; Y389-P419 HydrophobicContact CE2-CG 4.02Å
390I98.6Very high88.7Confident0 Ų034.9 Ų34.90%017%0.172CC..EExtended strand (participates in β ladder)trans-129131.5-179-58.1-177.7000110.5S98 K380 L383 H384 F387 L413 F414 A415S98-I390 PolarHBondContact N-O 3.26Å; S98-I390 PolarHBondContact O-N 2.83Å; K380-I390 HydrophobicContact CG-CD1 3.97Å; K380-I390 HydrophobicContact CG-CG2 4.16Å; L383-I390 HydrophobicContact CB-CD1 3.79Å; H384-I390 HydrophobicContact CB-CD1 4.49Å; F387-I390 HydrophobicContact CB-CG1 4.36Å; I390-L413 HydrophobicContact CG2-CD1 4.5Å; I390-L413 HydrophobicContact CG2-CD2 4.09Å; I390-L413 HydrophobicContact CG2-CG 4.24Å; I390-F414 CarbonylContact C-O 3.49Å; I390-F414 VanDerWaalsContact CA-O 3.32Å; I390-F414 WeakPolarHBondContact CA-O 3.5Å; I390-F414 WeakPolarHBondContact CG2-O 3.37Å; I390-A415 HydrophobicContact CD1-CB 4.44Å; I390-A415 HydrophobicContact CG1-CB 3.95Å
391I98.3Very high86.8Confident0 Ų037 Ų370%020%0.199CC..EExtended strand (participates in β ladder)trans-107.4125.2166.2-68.5-173.1000108.9Y95 I96 Y97 V394 L413 F414 I420 A423 L443 L445Y95-I391 HydrophobicContact CD2-CD1 4.42Å; Y95-I391 HydrophobicContact CD2-CG2 4.05Å; Y95-I391 HydrophobicContact CE2-CD1 4.38Å; Y95-I391 HydrophobicContact CG-CG2 4.05Å; I96-I391 CarbonylContact O-C 3.59Å; I96-I391 WeakPolarHBondContact O-CA 3.39Å; Y97-I391 HydrophobicContact CD2-CG1 4.11Å; I391-V394 HydrophobicContact CG2-CG2 3.68Å; I391-L413 CarbonylContact O-C 3.51Å; I391-L413 WeakPolarHBondContact O-CA 3.32Å; I391-F414 HydrophobicContact CB-CB 4.41Å; I391-F414 PolarHBondContact N-O 3.22Å; I391-F414 PolarHBondContact O-N 2.9Å; I391-I420 HydrophobicContact CD1-CD1 3.84Å; I391-I420 HydrophobicContact CD1-CG2 4.16Å; I391-I420 HydrophobicContact CG1-CD1 3.72Å; I391-A423 HydrophobicContact CD1-CB 3.38Å; I391-L443 HydrophobicContact CG2-CD1 4.37Å; I391-L443 HydrophobicContact CG2-CD2 4.22Å; I391-L445 HydrophobicContact CD1-CD2 3.73Å
392Y97.4Very high84.3Confident22 Ų2238.8 Ų38.89%0.08622%0.222CC..EExtended strand (participates in β ladder)trans-145.7177.1-17780.7-74.9000111.9I96 E377 K380 V394I96-Y392 HydrophobicContact CB-CD1 4.02Å; I96-Y392 HydrophobicContact CB-CE1 3.65Å; I96-Y392 HydrophobicContact CD1-CE1 4.43Å; I96-Y392 HydrophobicContact CD1-CE2 4.19Å; I96-Y392 HydrophobicContact CG2-CD1 4.27Å; I96-Y392 HydrophobicContact CG2-CE1 3.49Å; I96-Y392 VanDerWaalsContact CG2-CE1 3.49Å; I96-Y392 PolarHBondContact N-O 2.91Å; I96-Y392 WeakPolarHBondContact O-CD1 3.48Å; I96-Y392 PolarHBondContact O-N 3.18Å; E377-Y392 WeakPolarHBondContact OE1-CE2 3.23Å; E377-Y392 VanDerWaalsContact OE1-CZ 3.24Å; E377-Y392 PolarHBondContact OE1-OH 3.14Å; K380-Y392 HydrophobicContact CD-CD1 3.81Å; K380-Y392 HydrophobicContact CD-CE1 3.66Å; K380-Y392 HydrophobicContact CD-CE2 4.44Å; K380-Y392 HydrophobicContact CD-CG 4.25Å; K380-Y392 PolarHBondContact NZ-OH 3.48Å; Y392-V394 PolarHBondContact O-N 2.97Å
393D95.3Very high82.1Confident20 Ų2039 Ų3911%0.10723%0.227CC..SBendtrans47.744.9-171.8-157.97.2000111.4R92 I96 K373 Y397 N409R92-D393 IonicContact CZ-OD2 2.73Å; R92-D393 IonicContact NH2-OD1 2.69Å; R92-D393 IonicContact NH2-OD2 3.76Å; R92-D393 PolarHBondContact NH2-OD2 2.69Å; I96-D393 HydrophobicContact CD1-CB 3.95Å; I96-D393 HydrophobicContact CG1-CB 4.33Å; K373-D393 IonicContact NZ-OD1 3.87Å; K373-D393 PolarHBondContact NZ-OD1 2.8Å; K373-D393 IonicContact NZ-OD2 3.08Å; K373-D393 PolarHBondContact NZ-OD2 3.43Å; D393-Y397 PolarHBondContact OD1-OH 2.71Å; D393-N409 PolarHBondContact OD1-ND2 3.12Å
394V95.8Very high80.5Confident0 Ų042 Ų420%025%0.248CC..  trans-76.4132.1-179.7-178.80000108.6P94 I391 Y392 N409 S410 L412 Y425 L443P94-V394 CarbonylContact O-C 3.58Å; P94-V394 VanDerWaalsContact O-CA 3.29Å; P94-V394 WeakPolarHBondContact O-CA 3.45Å; I391-V394 HydrophobicContact CG2-CG2 3.68Å; Y392-V394 PolarHBondContact O-N 2.97Å; V394-N409 VanDerWaalsContact O-CB 3.3Å; V394-N409 WeakPolarHBondContact O-CB 3.11Å; V394-S410 WeakPolarHBondContact O-CB 3.49Å; V394-S410 PolarHBondContact O-N 3.46Å; V394-S410 PolarHBondContact O-OG 2.9Å; V394-L412 HydrophobicContact CB-CB 4.16Å; V394-L412 WeakPolarHBondContact CB-O 3.11Å; V394-L412 HydrophobicContact CG1-CB 4.28Å; V394-L412 WeakPolarHBondContact CG2-O 3.49Å; V394-Y425 HydrophobicContact CG1-CD1 4.39Å; V394-Y425 HydrophobicContact CG1-CD2 3.34Å; V394-Y425 HydrophobicContact CG1-CE2 3.97Å; V394-Y425 HydrophobicContact CG1-CG 3.59Å; V394-L443 HydrophobicContact CG1-CD1 4.1Å; V394-L443 HydrophobicContact CG2-CD1 4.39Å; V394-L443 HydrophobicContact CG2-CD2 4.17Å
395G90.6Very high79.5Confident0 Ų043.8 Ų43.80%026%0.256CS..SBendtrans139.8171.6178.500000113.3P94 S439P94-G395 PolarHBondContact O-N 2.92Å; G395-S439 VanDerWaalsContact CA-OG 3.31Å; G395-S439 WeakPolarHBondContact CA-OG 3.3Å
396V83.7Confident78.9Confident37 Ų3737.9 Ų37.922%0.22423%0.229CC..  trans-125139.2175.5-64.80000109.2P94 K406 Y425 C427 S439P94-V396 HydrophobicContact CB-CG1 4.48Å; V396-K406 WeakPolarHBondContact O-CB 3.21Å; V396-Y425 HydrophobicContact CG1-CE1 4.31Å; V396-Y425 HydrophobicContact CG2-CE1 4.44Å; V396-C427 HydrophobicContact CG2-CB 4.06Å; V396-S439 PolarHBondContact N-OG 3.48Å; V396-S439 VanDerWaalsContact O-CB 3.29Å; V396-S439 WeakPolarHBondContact O-CB 3.5Å
397Y74.3Confident78.3Confident8 Ų841.3 Ų41.33%0.03124%0.244CC..  trans-111.39.7-175-62.4-91.5000112.7W85 K373 D393 K406 N409W85-Y397 HydrophobicContact CH2-CD1 4.36Å; W85-Y397 HydrophobicContact CZ2-CD1 4.11Å; W85-Y397 HydrophobicContact CZ2-CG 4.22Å; K373-Y397 WeakPolarHBondContact CE-OH 3.44Å; K373-Y397 PolarHBondContact NZ-OH 2.82Å; D393-Y397 PolarHBondContact OD1-OH 2.71Å; Y397-K406 CarbonylContact C-O 3.6Å; Y397-K406 WeakPolarHBondContact CA-O 3.15Å; Y397-N409 HydrophobicContact CE1-CB 3.86Å; Y397-N409 VanDerWaalsContact CE1-N 3.34Å; Y397-N409 HydrophobicContact CE2-CB 3.99Å; Y397-N409 VanDerWaalsContact CZ-CB 3.44Å; Y397-N409 VanDerWaalsContact OH-CB 3.23Å; Y397-N409 WeakPolarHBondContact OH-CB 3.44Å; Y397-N409 PolarHBondContact OH-ND2 3.01Å
398S63.8Low77.8Confident11 Ų1143.6 Ų43.68%0.07726%0.258CS..SBendtrans-134.7161.2-17262.60000113.6Q89 H400Q89-S398 VanDerWaalsContact C-OG 3.31Å; Q89-S398 PolarHBondContact O-OG 2.88Å; S398-H400 PolarHBondContact O-N 2.79Å
399C54.8Low77.5Confident81 Ų8140.9 Ų40.955%0.54725%0.246SC..  trans-6778.8167.3-168.30000109.3G401 C403C399-G401 PolarHBondContact O-N 3.39Å; C399-G401 PolarHBondContact SG-O 3.17Å; C399-G401 VanDerWaalsContact SG-O 3.36Å; C399-C403 PolarHBondContact SG-O 2.79Å
400H46.8Very low77.4Confident124 Ų12440.2 Ų40.257%0.57424%0.243SC*.  trans-81.4102.6165.6-122.282000107.5S90 S398S90-H400 PolarHBondContact O-CE1 3.48Å; S90-H400 VanDerWaalsContact O-CE1 3.3Å; S398-H400 PolarHBondContact O-N 2.79Å
401G57.1Low77.3Confident66 Ų6640.2 Ų40.268%0.6824%0.243SC*.THydrogen-bonded Turntrans75-126.3-178.800000113.6C399C399-G401 PolarHBondContact O-N 3.39Å; C399-G401 PolarHBondContact SG-O 3.17Å; C399-G401 VanDerWaalsContact SG-O 3.36Å
402C44.6Very low77.3Confident141 Ų14140.4 Ų40.495%0.95324%0.244SC*.THydrogen-bonded Turntrans-90.18.3-174.4-67.70000114.9
403C51.2Low77.3Confident44 Ų4439.4 Ų39.430%0.29724%0.24SC..PPolyproline II helixtrans-87.5145.1-174.9-66.80000113C399C399-C403 PolarHBondContact SG-O 2.79Å
404S62.9Low77.5Confident64 Ų6438.4 Ų38.445%0.44824%0.235SC..PPolyproline II helixtrans-63.5154.9174.767.30000112.3K406S404-K406 PolarHBondContact O-N 2.78Å
405F74.9Confident77.6Confident58 Ų5838.4 Ų38.425%0.25424%0.235SC..PPolyproline II helixtrans-60.6128.8177.8-170.2-92.4000111.6F82 W85 F407F82-F405 HydrophobicContact CE2-CE1 4.26Å; F82-F405 AromaticContact CE2-CZ 3.92Å; F82-F405 HydrophobicContact CE2-CZ 3.92Å; F82-F405 HydrophobicContact CZ-CE1 4.28Å; F82-F405 AromaticContact CZ-CZ 3.85Å; F82-F405 HydrophobicContact CZ-CZ 3.85Å; W85-F405 HydrophobicContact CH2-CZ 4.5Å; W85-F405 HydrophobicContact CZ3-CE1 4.45Å; W85-F405 AromaticContact CZ3-CZ 3.86Å; W85-F405 HydrophobicContact CZ3-CZ 3.86Å; F405-F407 HydrophobicContact CD1-CD1 4.24Å; F405-F407 AromaticContact CD1-CD2 3.77Å; F405-F407 HydrophobicContact CD1-CD2 3.77Å; F405-F407 AromaticContact CD1-CE1 3.96Å; F405-F407 HydrophobicContact CD1-CE1 3.96Å; F405-F407 AromaticContact CD1-CE2 3.47Å; F405-F407 HydrophobicContact CD1-CE2 3.47Å; F405-F407 VanDerWaalsContact CD1-CE2 3.47Å; F405-F407 HydrophobicContact CD1-CG 4.15Å; F405-F407 AromaticContact CD1-CZ 3.57Å; F405-F407 HydrophobicContact CD1-CZ 3.57Å; F405-F407 AromaticContact CE1-CD1 3.67Å; F405-F407 HydrophobicContact CE1-CD1 3.67Å; F405-F407 HydrophobicContact CE1-CD2 4.04Å; F405-F407 AromaticContact CE1-CE1 3.46Å; F405-F407 HydrophobicContact CE1-CE1 3.46Å; F405-F407 VanDerWaalsContact CE1-CE1 3.46Å; F405-F407 AromaticContact CE1-CE2 3.87Å; F405-F407 HydrophobicContact CE1-CE2 3.87Å; F405-F407 AromaticContact CE1-CG 3.96Å; F405-F407 HydrophobicContact CE1-CG 3.96Å; F405-F407 AromaticContact CE1-CZ 3.57Å; F405-F407 HydrophobicContact CE1-CZ 3.57Å
406K83.5Confident78Confident6 Ų638.4 Ų38.43%0.02624%0.235CC..  trans-108.5122.8-179.6-56.6-56.6-172.1164.30110.5V396 Y397 S404 S436 L437 A438V396-K406 WeakPolarHBondContact O-CB 3.21Å; Y397-K406 CarbonylContact C-O 3.6Å; Y397-K406 WeakPolarHBondContact CA-O 3.15Å; S404-K406 PolarHBondContact O-N 2.78Å; K406-S436 VanDerWaalsContact CD-O 3.24Å; K406-S436 WeakPolarHBondContact CD-O 3.36Å; K406-S436 WeakPolarHBondContact CE-O 3.4Å; K406-S436 PolarHBondContact NZ-O 2.72Å; K406-L437 CarbonylContact C-O 3.37Å; K406-L437 WeakPolarHBondContact CA-O 3.45Å; K406-A438 WeakPolarHBondContact CD-O 3.03Å; K406-A438 PolarHBondContact NZ-O 3.04Å
407F82Confident78.6Confident111 Ų11139 Ų3949%0.48723%0.233SC..SBendtrans-88.8-27.3179.7-72.7-89000112.8F82 F405 L437F82-F407 HydrophobicContact CE2-CE1 4.31Å; F405-F407 HydrophobicContact CD1-CD1 4.24Å; F405-F407 AromaticContact CD1-CD2 3.77Å; F405-F407 HydrophobicContact CD1-CD2 3.77Å; F405-F407 AromaticContact CD1-CE1 3.96Å; F405-F407 HydrophobicContact CD1-CE1 3.96Å; F405-F407 AromaticContact CD1-CE2 3.47Å; F405-F407 HydrophobicContact CD1-CE2 3.47Å; F405-F407 VanDerWaalsContact CD1-CE2 3.47Å; F405-F407 HydrophobicContact CD1-CG 4.15Å; F405-F407 AromaticContact CD1-CZ 3.57Å; F405-F407 HydrophobicContact CD1-CZ 3.57Å; F405-F407 AromaticContact CE1-CD1 3.67Å; F405-F407 HydrophobicContact CE1-CD1 3.67Å; F405-F407 HydrophobicContact CE1-CD2 4.04Å; F405-F407 AromaticContact CE1-CE1 3.46Å; F405-F407 HydrophobicContact CE1-CE1 3.46Å; F405-F407 VanDerWaalsContact CE1-CE1 3.46Å; F405-F407 AromaticContact CE1-CE2 3.87Å; F405-F407 HydrophobicContact CE1-CE2 3.87Å; F405-F407 AromaticContact CE1-CG 3.96Å; F405-F407 HydrophobicContact CE1-CG 3.96Å; F405-F407 AromaticContact CE1-CZ 3.57Å; F405-F407 HydrophobicContact CE1-CZ 3.57Å; F407-L437 HydrophobicContact CD2-CB 4.28Å; F407-L437 HydrophobicContact CD2-CD2 3.78Å; F407-L437 HydrophobicContact CD2-CG 4.45Å; F407-L437 HydrophobicContact CE2-CD2 3.99Å; F407-L437 PolarHBondContact N-O 2.95Å
408V85.2Confident79.6Confident48 Ų4839 Ų3929%0.29123%0.233SC..BIsolated β-bridgetrans-122.9145.9-176.3-1680000108.9F371 L437 A438 S439F371-V408 HydrophobicContact CB-CG1 3.89Å; F371-V408 HydrophobicContact CD1-CG1 3.41Å; F371-V408 VanDerWaalsContact CD1-CG1 3.41Å; F371-V408 HydrophobicContact CE1-CG1 4.11Å; F371-V408 HydrophobicContact CG-CG1 3.86Å; V408-L437 PolarHBondContact N-O 2.87Å; V408-L437 VanDerWaalsContact N-O 3.12Å; V408-A438 HydrophobicContact CB-CB 4.47Å; V408-S439 PolarHBondContact O-N 2.83Å
409N89.9Confident81.1Confident4 Ų440.8 Ų40.82%0.02124%0.244CC..  trans-69.4-168.4176.161.88.5000111.9F371 D393 V394 Y397 G411 S439F371-N409 WeakPolarHBondContact CD1-OD1 3.42Å; F371-N409 WeakPolarHBondContact CE1-O 3.23Å; D393-N409 PolarHBondContact OD1-ND2 3.12Å; V394-N409 VanDerWaalsContact O-CB 3.3Å; V394-N409 WeakPolarHBondContact O-CB 3.11Å; Y397-N409 HydrophobicContact CE1-CB 3.86Å; Y397-N409 VanDerWaalsContact CE1-N 3.34Å; Y397-N409 HydrophobicContact CE2-CB 3.99Å; Y397-N409 VanDerWaalsContact CZ-CB 3.44Å; Y397-N409 VanDerWaalsContact OH-CB 3.23Å; Y397-N409 WeakPolarHBondContact OH-CB 3.44Å; Y397-N409 PolarHBondContact OH-ND2 3.01Å; N409-G411 VanDerWaalsContact C-N 3.28Å; N409-G411 PolarHBondContact O-N 2.69Å; N409-G411 PolarHBondContact OD1-N 3.03Å; N409-S439 WeakPolarHBondContact CA-OG 3.27Å; N409-S439 PolarHBondContact O-N 3.29Å
410S94.4Very high83.1Confident0 Ų037.4 Ų37.40%022%0.221CC..  trans-77.3-18.2-176.5730000113.1V394 L412 S439V394-S410 WeakPolarHBondContact O-CB 3.49Å; V394-S410 PolarHBondContact O-N 3.46Å; V394-S410 PolarHBondContact O-OG 2.9Å; S410-L412 PolarHBondContact O-N 3.37Å; S410-L412 WeakPolarHBondContact OG-CB 3.46Å; S410-L412 VanDerWaalsContact OG-CG 3.29Å; S410-L412 WeakPolarHBondContact OG-CG 3.32Å; S410-L412 PolarHBondContact OG-N 3.1Å; S410-L412 VanDerWaalsContact OG-N 3.08Å; S410-S439 WeakPolarHBondContact CA-O 3.4Å; S410-S439 WeakPolarHBondContact CB-O 3.39Å; S410-S439 PolarHBondContact N-OG 2.81Å
411G96.1Very high85.4Confident0 Ų033.2 Ų33.20%020%0.202CC..  trans69.110.9-17000000113.4Q368 E369 V370 N409Q368-G411 CarbonylContact C-O 3.59Å; Q368-G411 WeakPolarHBondContact CA-O 3.46Å; E369-G411 PolarHBondContact N-O 3.42Å; V370-G411 PolarHBondContact N-O 3.22Å; N409-G411 VanDerWaalsContact C-N 3.28Å; N409-G411 PolarHBondContact O-N 2.69Å; N409-G411 PolarHBondContact OD1-N 3.03Å
412L98.6Very high87.3Confident3 Ų331 Ų312%0.01617%0.174CC..  trans-85138.1177.9-56.1179.2000111.2L367 Q368 V394 S410 Y425 L443 H466L367-L412 WeakPolarHBondContact O-CA 3.22Å; Q368-L412 HydrophobicContact CG-CD2 4.01Å; V394-L412 HydrophobicContact CB-CB 4.16Å; V394-L412 WeakPolarHBondContact CB-O 3.11Å; V394-L412 HydrophobicContact CG1-CB 4.28Å; V394-L412 WeakPolarHBondContact CG2-O 3.49Å; S410-L412 PolarHBondContact O-N 3.37Å; S410-L412 WeakPolarHBondContact OG-CB 3.46Å; S410-L412 VanDerWaalsContact OG-CG 3.29Å; S410-L412 WeakPolarHBondContact OG-CG 3.32Å; S410-L412 PolarHBondContact OG-N 3.1Å; S410-L412 VanDerWaalsContact OG-N 3.08Å; L412-Y425 HydrophobicContact CD1-CE2 4.4Å; L412-L443 HydrophobicContact CD1-CB 3.94Å; L412-H466 HydrophobicContact CD2-CB 4.05Å
413L98.7Very high89.8Confident1 Ų124.4 Ų24.41%0.00513%0.13CC..EExtended strand (participates in β ladder)trans-137.1139.9168.8-178156.8000108.9L367 V370 L379 L383 I390 I391 A415L367-L413 HydrophobicContact CB-CB 4.26Å; L367-L413 HydrophobicContact CD1-CD2 4.06Å; L367-L413 HydrophobicContact CG-CD2 4.43Å; L367-L413 PolarHBondContact N-O 3.48Å; L367-L413 PolarHBondContact O-N 3.2Å; V370-L413 HydrophobicContact CB-CB 4.39Å; V370-L413 HydrophobicContact CG1-CD1 4.25Å; V370-L413 HydrophobicContact CG2-CB 3.99Å; L379-L413 HydrophobicContact CD2-CD1 4.36Å; L383-L413 HydrophobicContact CD1-CD2 3.99Å; I390-L413 HydrophobicContact CG2-CD1 4.5Å; I390-L413 HydrophobicContact CG2-CD2 4.09Å; I390-L413 HydrophobicContact CG2-CG 4.24Å; I391-L413 CarbonylContact O-C 3.51Å; I391-L413 WeakPolarHBondContact O-CA 3.32Å; L413-A415 HydrophobicContact CD2-CB 4.39Å
414F98.8Very high92Very high0 Ų022.9 Ų22.90%012%0.121CC..EExtended strand (participates in β ladder)trans-123.7136.3174.1174.6-96.4000110.3F364 L365 I390 I391 S416 I420 L443 L445 V447 I462F364-F414 HydrophobicContact CB-CE2 4.19Å; F364-F414 HydrophobicContact CB-CZ 4.45Å; F364-F414 HydrophobicContact CD1-CE2 4.37Å; F364-F414 AromaticContact CD1-CZ 3.83Å; F364-F414 HydrophobicContact CD1-CZ 3.83Å; L365-F414 CarbonylContact O-C 3.36Å; L365-F414 WeakPolarHBondContact O-CA 3.19Å; I390-F414 CarbonylContact C-O 3.49Å; I390-F414 VanDerWaalsContact CA-O 3.32Å; I390-F414 WeakPolarHBondContact CA-O 3.5Å; I390-F414 WeakPolarHBondContact CG2-O 3.37Å; I391-F414 HydrophobicContact CB-CB 4.41Å; I391-F414 PolarHBondContact N-O 3.22Å; I391-F414 PolarHBondContact O-N 2.9Å; F414-S416 VanDerWaalsContact CE1-CB 3.48Å; F414-I420 HydrophobicContact CD1-CD1 3.79Å; F414-I420 HydrophobicContact CE1-CD1 3.74Å; F414-I420 HydrophobicContact CE1-CG1 4.05Å; F414-L443 HydrophobicContact CB-CD2 3.86Å; F414-L445 HydrophobicContact CB-CD1 4.14Å; F414-L445 HydrophobicContact CB-CD2 4.19Å; F414-L445 HydrophobicContact CD1-CD1 4.17Å; F414-L445 HydrophobicContact CD1-CD2 3.28Å; F414-L445 HydrophobicContact CD1-CG 4.32Å; F414-L445 HydrophobicContact CD2-CD1 3.66Å; F414-L445 HydrophobicContact CD2-CD2 4.32Å; F414-L445 HydrophobicContact CE1-CD1 4.46Å; F414-L445 HydrophobicContact CE1-CD2 3.55Å; F414-L445 HydrophobicContact CE1-CG 4.47Å; F414-L445 HydrophobicContact CE2-CD1 4Å; F414-L445 HydrophobicContact CG-CD1 3.72Å; F414-L445 HydrophobicContact CG-CD2 3.67Å; F414-L445 HydrophobicContact CG-CG 4.35Å; F414-L445 HydrophobicContact CZ-CD1 4.36Å; F414-L445 HydrophobicContact CZ-CD2 4.17Å; F414-V447 HydrophobicContact CE1-CG1 4.5Å; F414-V447 HydrophobicContact CZ-CG1 4.34Å; F414-I462 HydrophobicContact CE2-CB 4.37Å; F414-I462 HydrophobicContact CE2-CD1 3.87Å; F414-I462 HydrophobicContact CE2-CG2 3.99Å; F414-I462 HydrophobicContact CZ-CD1 3.83Å
415A98.7Very high93.6Very high0 Ų020.9 Ų20.90%010%0.103CC..EExtended strand (participates in β ladder)trans-129.1139.7173.800000110.4F364 L365 F387 Y389 I390 L413F364-A415 WeakPolarHBondContact CA-O 3.44Å; L365-A415 HydrophobicContact CB-CB 4.31Å; L365-A415 PolarHBondContact N-O 3.25Å; L365-A415 PolarHBondContact O-N 3.18Å; F387-A415 HydrophobicContact CB-CB 3.86Å; F387-A415 HydrophobicContact CD1-CB 4.16Å; F387-A415 HydrophobicContact CD2-CB 3.75Å; F387-A415 HydrophobicContact CE2-CB 4.3Å; F387-A415 HydrophobicContact CG-CB 3.66Å; Y389-A415 CarbonylContact O-C 3.52Å; Y389-A415 WeakPolarHBondContact O-CA 3.37Å; I390-A415 HydrophobicContact CD1-CB 4.44Å; I390-A415 HydrophobicContact CG1-CB 3.95Å; L413-A415 HydrophobicContact CD2-CB 4.39Å
416S98.2Very high94.6Very high0 Ų020.9 Ų20.90%010%0.104CC..EExtended strand (participates in β ladder)trans-142.6147.4-177.5-173.20000112.6D363 F364 E388 Y389 F414 Y418D363-S416 WeakPolarHBondContact O-CA 3.42Å; F364-S416 WeakPolarHBondContact CD1-OG 3.45Å; F364-S416 WeakPolarHBondContact CE1-OG 3.47Å; E388-S416 PolarHBondContact N-O 3.47Å; Y389-S416 PolarHBondContact N-O 2.85Å; Y389-S416 PolarHBondContact O-N 2.78Å; F414-S416 VanDerWaalsContact CE1-CB 3.48Å; S416-Y418 VanDerWaalsContact C-N 3.33Å; S416-Y418 PolarHBondContact OG-N 2.92Å; S416-Y418 PolarHBondContact OG-O 3.38Å; S416-Y418 VanDerWaalsContact OG-O 3.08Å
417R96.2Very high95.1Very high49 Ų4921.8 Ų21.819%0.18511%0.111CC..SBendtrans-84.4-11.9166.7-55.8-17564.6-171.3-0.8113L112 L362 D363 Y386 F387L112-R417 HydrophobicContact CD1-CB 3.48Å; L112-R417 VanDerWaalsContact CD1-CB 3.48Å; L112-R417 WeakPolarHBondContact CD1-O 3.3Å; L362-R417 VanDerWaalsContact O-CD 3.22Å; L362-R417 WeakPolarHBondContact O-CD 3.42Å; D363-R417 PolarHBondContact O-N 3.42Å; Y386-R417 HydrophobicContact CE1-CG 4.05Å; F387-R417 HydrophobicContact CD1-CG 3.78Å; F387-R417 HydrophobicContact CE1-CG 4.06Å
418Y96Very high95.7Very high9 Ų916.7 Ų16.74%0.0359%0.088CC..SBendtrans-108145-177-71.7-82.5000111L112 F124 D363 F364 Y389 S416 I420 V449L112-Y418 HydrophobicContact CD1-CD1 4.49Å; L112-Y418 HydrophobicContact CD1-CD2 4.46Å; L112-Y418 HydrophobicContact CD1-CE1 4.2Å; L112-Y418 HydrophobicContact CD1-CE2 4.13Å; F124-Y418 HydrophobicContact CD1-CE2 4.21Å; F124-Y418 HydrophobicContact CE1-CE2 4.14Å; F124-Y418 AromaticContact CE1-CZ 3.97Å; D363-Y418 HydrophobicContact CB-CD2 4.2Å; D363-Y418 HydrophobicContact CB-CE2 3.94Å; F364-Y418 AromaticContact CE1-CD2 3.93Å; F364-Y418 HydrophobicContact CE1-CD2 3.93Å; F364-Y418 HydrophobicContact CE1-CG 4.4Å; F364-Y418 HydrophobicContact CE2-CD2 4.37Å; F364-Y418 AromaticContact CZ-CD2 3.58Å; F364-Y418 HydrophobicContact CZ-CD2 3.58Å; F364-Y418 HydrophobicContact CZ-CE2 4.3Å; F364-Y418 HydrophobicContact CZ-CG 4.21Å; Y389-Y418 WeakPolarHBondContact CD2-O 3.49Å; S416-Y418 VanDerWaalsContact C-N 3.33Å; S416-Y418 PolarHBondContact OG-N 2.92Å; S416-Y418 PolarHBondContact OG-O 3.38Å; S416-Y418 VanDerWaalsContact OG-O 3.08Å; Y418-I420 PolarHBondContact O-N 2.9Å; Y418-V449 HydrophobicContact CD1-CB 4.15Å; Y418-V449 HydrophobicContact CD1-CG1 4.17Å; Y418-V449 HydrophobicContact CD2-CG1 4.43Å; Y418-V449 HydrophobicContact CE1-CB 4.24Å; Y418-V449 WeakPolarHBondContact CE1-O 2.86Å; Y418-V449 HydrophobicContact CG-CG1 4.06Å
419P95.1Very high96Very high48 Ų4817.9 Ų17.931%0.31210%0.097SC..  trans-56.4130.9179.5-23.430000112.6Y389 V447 Q448Y389-P419 HydrophobicContact CE1-CB 4.24Å; Y389-P419 HydrophobicContact CE2-CB 4.36Å; Y389-P419 HydrophobicContact CE2-CG 4.02Å; P419-V447 CarbonylContact O-C 3.6Å; P419-V447 WeakPolarHBondContact O-CA 3.42Å; P419-Q448 WeakPolarHBondContact CD-O 3.36Å; P419-Q448 PolarHBondContact O-N 3.25Å
420I96.6Very high95.9Very high10 Ų1019.1 Ų19.15%0.05110%0.104CC..EExtended strand (participates in β ladder)trans-82.8130.5171.7-54171.7000107.9L3 Y97 I391 F414 Y418 A423 L445 V447L3-I420 HydrophobicContact CD1-CB 4.24Å; L3-I420 HydrophobicContact CD1-CG2 4.28Å; L3-I420 VanDerWaalsContact CD1-O 3.26Å; L3-I420 WeakPolarHBondContact CD1-O 3.29Å; L3-I420 HydrophobicContact CD2-CG2 4.16Å; Y97-I420 HydrophobicContact CD2-CD1 4.27Å; Y97-I420 HydrophobicContact CE2-CB 4.37Å; Y97-I420 HydrophobicContact CE2-CD1 4.19Å; I391-I420 HydrophobicContact CD1-CD1 3.84Å; I391-I420 HydrophobicContact CD1-CG2 4.16Å; I391-I420 HydrophobicContact CG1-CD1 3.72Å; F414-I420 HydrophobicContact CD1-CD1 3.79Å; F414-I420 HydrophobicContact CE1-CD1 3.74Å; F414-I420 HydrophobicContact CE1-CG1 4.05Å; Y418-I420 PolarHBondContact O-N 2.9Å; I420-A423 HydrophobicContact CG2-CB 4.48Å; I420-L445 HydrophobicContact CD1-CD2 4.19Å; I420-L445 HydrophobicContact CG2-CD2 4.19Å; I420-V447 HydrophobicContact CG1-CG1 4.25Å
421M94.8Very high95.4Very high36 Ų3620 Ų2018%0.17711%0.113CC..EExtended strand (participates in β ladder)trans-97.9-48.8179.4-60.8179.76600111.3K446 Q448 R457 V459M421-K446 HydrophobicContact CB-CG 4.47Å; M421-K446 PolarHBondContact N-O 2.97Å; M421-K446 HydrophobicContact SD-CD 4.4Å; M421-K446 HydrophobicContact SD-CG 4.35Å; M421-Q448 HydrophobicContact CG-CB 4.02Å; M421-Q448 HydrophobicContact SD-CB 3.81Å; M421-R457 VanDerWaalsContact CE-CD 3.47Å; M421-V459 HydrophobicContact SD-CG1 3.73Å
422D97Very high95Very high18 Ų1824.2 Ų24.210%0.09613%0.131CC..EExtended strand (participates in β ladder)trans-138.3143.9-176.3-62.4-82.7000109.4M1 L445 K446 F491 T495M1-D422 WeakPolarHBondContact CA-OD1 3.47Å; M1-D422 HydrophobicContact CB-CB 4.44Å; M1-D422 VanDerWaalsContact CB-OD1 3.22Å; M1-D422 WeakPolarHBondContact CB-OD1 3.27Å; M1-D422 WeakPolarHBondContact CG-OD1 3.34Å; M1-D422 PolarHBondContact N-OD1 3.13Å; M1-D422 HydrophobicContact SD-CB 4.47Å; D422-L445 WeakPolarHBondContact O-CA 3.48Å; D422-K446 HydrophobicContact CB-CB 4.04Å; D422-K446 PolarHBondContact N-O 3.36Å; D422-K446 PolarHBondContact O-N 3.18Å; D422-F491 HydrophobicContact CB-CE2 4.36Å; D422-F491 HydrophobicContact CB-CZ 4.02Å; D422-T495 HydrophobicContact CB-CG2 3.68Å
423A97.6Very high94.4Very high3 Ų326.5 Ų26.53%0.02516%0.155CC..EExtended strand (participates in β ladder)trans-145.1134.5173.300000110.8L3 Y95 I391 I420 F444 L445L3-A423 HydrophobicContact CD2-CB 3.89Å; Y95-A423 HydrophobicContact CE1-CB 4.06Å; Y95-A423 WeakPolarHBondContact CE1-O 3.41Å; Y95-A423 HydrophobicContact CE2-CB 4.28Å; Y95-A423 PolarHBondContact OH-O 2.89Å; I391-A423 HydrophobicContact CD1-CB 3.38Å; I420-A423 HydrophobicContact CG2-CB 4.48Å; A423-F444 CarbonylContact C-O 3.57Å; A423-F444 VanDerWaalsContact CA-O 3.23Å; A423-F444 WeakPolarHBondContact CA-O 3.17Å; A423-L445 HydrophobicContact CB-CD2 4.44Å
424A97.1Very high93.6Very high13 Ų1331.6 Ų31.611%0.10719%0.187CC..EExtended strand (participates in β ladder)trans-133.7145.5176.100000109.9M1 F444 F491M1-A424 HydrophobicContact SD-CB 4.47Å; A424-F444 PolarHBondContact N-O 3.09Å; A424-F444 PolarHBondContact O-N 2.95Å; A424-F491 HydrophobicContact CB-CD2 3.62Å; A424-F491 HydrophobicContact CB-CE2 3.65Å
425Y96.9Very high92.9Very high21 Ų2132.6 Ų32.68%0.08219%0.192CC..EExtended strand (participates in β ladder)trans-129.3134.7176.4163.2-95.6000109.6P94 V394 V396 L412 C427 S439 A442P94-Y425 HydrophobicContact CB-CD1 4.12Å; V394-Y425 HydrophobicContact CG1-CD1 4.39Å; V394-Y425 HydrophobicContact CG1-CD2 3.34Å; V394-Y425 HydrophobicContact CG1-CE2 3.97Å; V394-Y425 HydrophobicContact CG1-CG 3.59Å; V396-Y425 HydrophobicContact CG1-CE1 4.31Å; V396-Y425 HydrophobicContact CG2-CE1 4.44Å; L412-Y425 HydrophobicContact CD1-CE2 4.4Å; Y425-C427 HydrophobicContact CE1-CB 4.08Å; Y425-C427 WeakPolarHBondContact OH-CA 2.97Å; Y425-C427 WeakPolarHBondContact OH-CB 3.41Å; Y425-S439 WeakPolarHBondContact OH-CB 3.31Å; Y425-S439 PolarHBondContact OH-O 3.12Å; Y425-S439 PolarHBondContact OH-OG 3.29Å; Y425-A442 WeakPolarHBondContact CA-O 3.21Å; Y425-A442 WeakPolarHBondContact CD2-O 3.11Å
426H95.4Very high92.2Very high59 Ų5934.1 Ų34.127%0.27320%0.203SC..EExtended strand (participates in β ladder)trans-125.5128.2178.4-65.8-102.7000109.7G441 A442 F444 W487H426-G441 CarbonylContact O-C 3.51Å; H426-G441 WeakPolarHBondContact O-CA 3.3Å; H426-A442 PolarHBondContact N-O 2.97Å; H426-A442 PolarHBondContact O-N 3.13Å; H426-F444 HydrophobicContact CB-CE2 4.31Å; H426-F444 AromaticContact CD2-CD2 3.77Å; H426-F444 AromaticContact CD2-CE2 3.6Å; H426-W487 HydrophobicContact CB-CD2 3.7Å; H426-W487 HydrophobicContact CB-CE3 3.42Å; H426-W487 VanDerWaalsContact CB-CE3 3.42Å; H426-W487 HydrophobicContact CB-CG 4.45Å; H426-W487 HydrophobicContact CB-CH2 3.82Å; H426-W487 HydrophobicContact CB-CZ2 4.09Å; H426-W487 HydrophobicContact CB-CZ3 3.47Å; H426-W487 VanDerWaalsContact CB-CZ3 3.47Å; H426-W487 AromaticContact CG-CD2 3.91Å
427C94.6Very high91.6Very high25 Ų2537.8 Ų37.817%0.16922%0.222CC..EExtended strand (participates in β ladder)trans-88.4134.8176.2-176.30000109.8V396 Y425 K440V396-C427 HydrophobicContact CG2-CB 4.06Å; Y425-C427 HydrophobicContact CE1-CB 4.08Å; Y425-C427 WeakPolarHBondContact OH-CA 2.97Å; Y425-C427 WeakPolarHBondContact OH-CB 3.41Å; C427-K440 PolarHBondContact SG-O 3.17Å
428Y94Very high91.2Very high3 Ų336 Ų361%0.01222%0.217CC..  trans-69.7132171.2-62.4-59.4000110.3K440 G441 T465 L467 Q480 M483 W487Y428-K440 PolarHBondContact N-O 2.85Å; Y428-G441 VanDerWaalsContact CD2-CA 3.44Å; Y428-G441 VanDerWaalsContact CE2-CA 3.47Å; Y428-T465 PolarHBondContact OH-OG1 3.47Å; Y428-L467 HydrophobicContact CD2-CD2 4.47Å; Y428-L467 HydrophobicContact CE2-CD2 3.54Å; Y428-Q480 HydrophobicContact CD1-CB 3.88Å; Y428-Q480 HydrophobicContact CD1-CG 3.67Å; Y428-Q480 HydrophobicContact CD2-CB 4.37Å; Y428-Q480 HydrophobicContact CD2-CG 3.98Å; Y428-Q480 HydrophobicContact CE1-CB 3.79Å; Y428-Q480 HydrophobicContact CE1-CG 4.13Å; Y428-Q480 WeakPolarHBondContact CE1-O 3.46Å; Y428-Q480 HydrophobicContact CE2-CB 4.33Å; Y428-Q480 HydrophobicContact CE2-CG 4.44Å; Y428-Q480 HydrophobicContact CG-CB 4.18Å; Y428-Q480 HydrophobicContact CG-CG 3.6Å; Y428-M483 HydrophobicContact CD1-CB 4.35Å; Y428-M483 HydrophobicContact CD1-CE 4.04Å; Y428-M483 HydrophobicContact CD1-SD 4.35Å; Y428-M483 HydrophobicContact CE1-CB 4.19Å; Y428-W487 AromaticContact CD1-CH2 3.67Å; Y428-W487 HydrophobicContact CD1-CH2 3.67Å; Y428-W487 AromaticContact CD1-CZ3 3.52Å; Y428-W487 HydrophobicContact CD1-CZ3 3.52Å; Y428-W487 HydrophobicContact CE1-CE3 4.18Å; Y428-W487 AromaticContact CE1-CH2 3.98Å; Y428-W487 HydrophobicContact CE1-CH2 3.98Å; Y428-W487 AromaticContact CE1-CZ3 3.36Å; Y428-W487 HydrophobicContact CE1-CZ3 3.36Å; Y428-W487 HydrophobicContact CG-CZ3 4.49Å
429P90.4Very high91Very high73 Ų7335.5 Ų35.547%0.47422%0.215SC..THydrogen-bonded Turntrans-80.2-19.4-176.931.7-35.9000113.4M483P429-M483 WeakPolarHBondContact CD-SD 3.49Å; P429-M483 HydrophobicContact CG-CE 4.17Å; P429-M483 HydrophobicContact CG-SD 3.85Å
430N88.9Confident90.9Very high31 Ų3133.7 Ų33.717%0.16620%0.203CC..THydrogen-bonded Turntrans-104.819.9-164.166.8-13.1000114.8V476 E479 Q480N430-V476 PolarHBondContact ND2-O 2.9Å; N430-V476 WeakPolarHBondContact O-CG1 3.1Å; N430-E479 WeakPolarHBondContact ND2-CB 3.48Å; N430-E479 PolarHBondContact ND2-OE2 3.22Å; N430-Q480 WeakPolarHBondContact OD1-CG 3.21Å; N430-Q480 PolarHBondContact OD1-NE2 3.22Å
431G84.2Confident90.9Very high18 Ų1833.2 Ų33.219%0.18620%0.2CC..  trans-60.8139.217800000112.9S436G431-S436 WeakPolarHBondContact O-CB 3.39Å
432K86.6Confident91.1Very high89 Ų8931.5 Ų31.539%0.38719%0.192SC..  trans-117.2158.6-177.1-71.8-173.8-172.6169.10112.9D435 S436 Q468 I470 D473 V476K432-D435 WeakPolarHBondContact O-CB 3.42Å; K432-D435 PolarHBondContact O-N 3.44Å; K432-S436 PolarHBondContact O-N 2.87Å; K432-Q468 PolarHBondContact O-NE2 3.04Å; K432-Q468 VanDerWaalsContact O-NE2 3.11Å; K432-I470 HydrophobicContact CB-CD1 4.44Å; K432-D473 WeakPolarHBondContact CD-OD1 3.45Å; K432-D473 WeakPolarHBondContact CD-OD2 3.38Å; K432-D473 IonicContact NZ-OD1 3.64Å; K432-D473 PolarHBondContact NZ-OD1 3.43Å; K432-V476 HydrophobicContact CD-CG2 3.86Å; K432-V476 VanDerWaalsContact CE-CG2 3.42Å; K432-V476 HydrophobicContact CG-CG2 4.24Å
433G86.5Confident91.2Very high50 Ų5030.7 Ų30.752%0.51519%0.187SC..G310 helixtrans59.1-136178.100000112.4D435 S436G433-D435 VanDerWaalsContact C-N 3.29Å; G433-D435 PolarHBondContact O-N 2.84Å; G433-S436 VanDerWaalsContact O-CB 3.3Å; G433-S436 WeakPolarHBondContact O-CB 3.37Å; G433-S436 PolarHBondContact O-N 3.39Å; G433-S436 PolarHBondContact O-OG 3.15Å
434T81.6Confident91.2Very high109 Ų10930.5 Ų30.567%0.66919%0.186SC*.G310 helixtrans-64.1-33.1177.346.50000112.7S436 L437T434-S436 PolarHBondContact O-N 2.94Å; T434-L437 WeakPolarHBondContact O-CB 3.29Å; T434-L437 PolarHBondContact O-N 3.19Å
435D84.1Confident91.3Very high21 Ų2129.9 Ų29.911%0.11218%0.181CC..G310 helixtrans-64.9-21.6177.5-74.912.3000112.3K432 G433 L437 A438 K440 A469K432-D435 WeakPolarHBondContact O-CB 3.42Å; K432-D435 PolarHBondContact O-N 3.44Å; G433-D435 VanDerWaalsContact C-N 3.29Å; G433-D435 PolarHBondContact O-N 2.84Å; D435-L437 PolarHBondContact O-N 3.43Å; D435-A438 PolarHBondContact O-N 3.18Å; D435-A438 VanDerWaalsContact O-N 3.1Å; D435-A438 VanDerWaalsContact O-O 3.04Å; D435-K440 HydrophobicContact CB-CD 4.21Å; D435-K440 IonicContact OD1-NZ 3.72Å; D435-K440 WeakPolarHBondContact OD2-CD 3.38Å; D435-K440 WeakPolarHBondContact OD2-CE 3.43Å; D435-K440 IonicContact OD2-NZ 2.72Å; D435-K440 PolarHBondContact OD2-NZ 3.14Å; D435-A469 WeakPolarHBondContact OD2-CB 3.23Å; D435-A469 PolarHBondContact OD2-N 3.17Å
436S84.6Confident91.3Very high32 Ų3229 Ų2922%0.22418%0.177CC..G310 helixtrans-61.6-23173.575.10000112.9K406 G431 K432 G433 T434K406-S436 VanDerWaalsContact CD-O 3.24Å; K406-S436 WeakPolarHBondContact CD-O 3.36Å; K406-S436 WeakPolarHBondContact CE-O 3.4Å; K406-S436 PolarHBondContact NZ-O 2.72Å; G431-S436 WeakPolarHBondContact O-CB 3.39Å; K432-S436 PolarHBondContact O-N 2.87Å; G433-S436 VanDerWaalsContact O-CB 3.3Å; G433-S436 WeakPolarHBondContact O-CB 3.37Å; G433-S436 PolarHBondContact O-N 3.39Å; G433-S436 PolarHBondContact O-OG 3.15Å; T434-S436 PolarHBondContact O-N 2.94Å
437L85.3Confident91.4Very high77 Ų7726.1 Ų26.140%0.40316%0.164SC..G310 helixtrans-88-15.9178.5-53.6177.4000112.8K406 F407 V408 T434 D435K406-L437 CarbonylContact C-O 3.37Å; K406-L437 WeakPolarHBondContact CA-O 3.45Å; F407-L437 HydrophobicContact CD2-CB 4.28Å; F407-L437 HydrophobicContact CD2-CD2 3.78Å; F407-L437 HydrophobicContact CD2-CG 4.45Å; F407-L437 HydrophobicContact CE2-CD2 3.99Å; F407-L437 PolarHBondContact N-O 2.95Å; V408-L437 PolarHBondContact N-O 2.87Å; V408-L437 VanDerWaalsContact N-O 3.12Å; T434-L437 WeakPolarHBondContact O-CB 3.29Å; T434-L437 PolarHBondContact O-N 3.19Å; D435-L437 PolarHBondContact O-N 3.43Å
438A88.6Confident91.4Very high10 Ų1027.4 Ų27.48%0.08317%0.167CC..BIsolated β-bridgetrans-93.6145.9173.300000110.4F371 K406 V408 D435 K440F371-A438 HydrophobicContact CE1-CB 4.49Å; K406-A438 WeakPolarHBondContact CD-O 3.03Å; K406-A438 PolarHBondContact NZ-O 3.04Å; V408-A438 HydrophobicContact CB-CB 4.47Å; D435-A438 PolarHBondContact O-N 3.18Å; D435-A438 VanDerWaalsContact O-N 3.1Å; D435-A438 VanDerWaalsContact O-O 3.04Å; A438-K440 HydrophobicContact CB-CG 4.31Å; A438-K440 PolarHBondContact O-N 3.38Å
439S91.6Very high91.4Very high0 Ų027.4 Ų27.40%017%0.168CC..THydrogen-bonded Turntrans-82.460.5171.575.40000110G395 V396 V408 N409 S410 Y425G395-S439 VanDerWaalsContact CA-OG 3.31Å; G395-S439 WeakPolarHBondContact CA-OG 3.3Å; V396-S439 PolarHBondContact N-OG 3.48Å; V396-S439 VanDerWaalsContact O-CB 3.29Å; V396-S439 WeakPolarHBondContact O-CB 3.5Å; V408-S439 PolarHBondContact O-N 2.83Å; N409-S439 WeakPolarHBondContact CA-OG 3.27Å; N409-S439 PolarHBondContact O-N 3.29Å; S410-S439 WeakPolarHBondContact CA-O 3.4Å; S410-S439 WeakPolarHBondContact CB-O 3.39Å; S410-S439 PolarHBondContact N-OG 2.81Å; Y425-S439 WeakPolarHBondContact OH-CB 3.31Å; Y425-S439 PolarHBondContact OH-O 3.12Å; Y425-S439 PolarHBondContact OH-OG 3.29Å
440K93.4Very high91.4Very high10 Ų1024 Ų244%0.04315%0.146CC..  trans-59.1141.3172.8-75.5-164167.9-168.50110.1C427 Y428 D435 A438 H466 L467C427-K440 PolarHBondContact SG-O 3.17Å; Y428-K440 PolarHBondContact N-O 2.85Å; D435-K440 HydrophobicContact CB-CD 4.21Å; D435-K440 IonicContact OD1-NZ 3.72Å; D435-K440 WeakPolarHBondContact OD2-CD 3.38Å; D435-K440 WeakPolarHBondContact OD2-CE 3.43Å; D435-K440 IonicContact OD2-NZ 2.72Å; D435-K440 PolarHBondContact OD2-NZ 3.14Å; A438-K440 HydrophobicContact CB-CG 4.31Å; A438-K440 PolarHBondContact O-N 3.38Å; K440-H466 VanDerWaalsContact CE-CE1 3.49Å; K440-H466 WeakPolarHBondContact CE-CE1 3.48Å; K440-H466 WeakPolarHBondContact CE-NE2 3.41Å; K440-H466 PolarHBondContact NZ-CD2 3.12Å; K440-H466 PolarHBondContact NZ-CE1 3.43Å; K440-H466 PolarHBondContact NZ-NE2 3.48Å; K440-L467 WeakPolarHBondContact CD-O 3.47Å; K440-L467 PolarHBondContact NZ-O 3.05Å
441G95.9Very high91.5Very high0 Ų022.9 Ų22.90%014%0.14CC..EExtended strand (participates in β ladder)trans-179.3-170.3-167.300000113.4H426 Y428 T465 H466H426-G441 CarbonylContact O-C 3.51Å; H426-G441 WeakPolarHBondContact O-CA 3.3Å; Y428-G441 VanDerWaalsContact CD2-CA 3.44Å; Y428-G441 VanDerWaalsContact CE2-CA 3.47Å; G441-T465 WeakPolarHBondContact O-CA 3.32Å; G441-T465 PolarHBondContact O-OG1 3.26Å; G441-H466 PolarHBondContact O-N 3.2Å
442A98.3Very high91.6Very high0 Ų022.3 Ų22.30%013%0.134CC..EExtended strand (participates in β ladder)trans-122.9135.3177.800000111Y425 H426 F444 C464 L484Y425-A442 WeakPolarHBondContact CA-O 3.21Å; Y425-A442 WeakPolarHBondContact CD2-O 3.11Å; H426-A442 PolarHBondContact N-O 2.97Å; H426-A442 PolarHBondContact O-N 3.13Å; A442-F444 HydrophobicContact CB-CE1 4.35Å; A442-F444 HydrophobicContact CB-CE2 3.64Å; A442-F444 HydrophobicContact CB-CZ 3.51Å; A442-C464 CarbonylContact C-O 3.54Å; A442-C464 WeakPolarHBondContact CA-O 3.29Å; A442-L484 HydrophobicContact CB-CD1 3.82Å
443L98.7Very high91.5Very high0 Ų021.8 Ų21.80%014%0.139CC..EExtended strand (participates in β ladder)trans-105.4123.7172.4176.970.2000108.6I391 V394 L412 F414 L445 S463 C464I391-L443 HydrophobicContact CG2-CD1 4.37Å; I391-L443 HydrophobicContact CG2-CD2 4.22Å; V394-L443 HydrophobicContact CG1-CD1 4.1Å; V394-L443 HydrophobicContact CG2-CD1 4.39Å; V394-L443 HydrophobicContact CG2-CD2 4.17Å; L412-L443 HydrophobicContact CD1-CB 3.94Å; F414-L443 HydrophobicContact CB-CD2 3.86Å; L443-L445 HydrophobicContact CD2-CD1 3.9Å; L443-L445 HydrophobicContact CD2-CG 4.44Å; L443-L445 HydrophobicContact CG-CD1 3.88Å; L443-L445 HydrophobicContact CG-CG 4.22Å; L443-S463 CarbonylContact O-C 3.56Å; L443-S463 VanDerWaalsContact O-CA 3.26Å; L443-S463 WeakPolarHBondContact O-CA 3.42Å; L443-C464 PolarHBondContact N-O 2.91Å; L443-C464 PolarHBondContact O-N 3.23Å
444F98.7Very high91.4Very high0 Ų026 Ų260%015%0.145CC..EExtended strand (participates in β ladder)trans-110.1134.1-179.9-55.1-87000109.6A423 A424 H426 A442 S463 L484 W487 L488 F491A423-F444 CarbonylContact C-O 3.57Å; A423-F444 VanDerWaalsContact CA-O 3.23Å; A423-F444 WeakPolarHBondContact CA-O 3.17Å; A424-F444 PolarHBondContact N-O 3.09Å; A424-F444 PolarHBondContact O-N 2.95Å; H426-F444 HydrophobicContact CB-CE2 4.31Å; H426-F444 AromaticContact CD2-CD2 3.77Å; H426-F444 AromaticContact CD2-CE2 3.6Å; A442-F444 HydrophobicContact CB-CE1 4.35Å; A442-F444 HydrophobicContact CB-CE2 3.64Å; A442-F444 HydrophobicContact CB-CZ 3.51Å; F444-S463 VanDerWaalsContact CD1-OG 3.26Å; F444-S463 WeakPolarHBondContact CD1-OG 3.13Å; F444-L484 HydrophobicContact CE1-CD1 3.96Å; F444-L484 HydrophobicContact CZ-CD1 3.96Å; F444-W487 HydrophobicContact CE1-CB 4.17Å; F444-W487 HydrophobicContact CE2-CB 3.83Å; F444-W487 HydrophobicContact CE2-CE3 4.33Å; F444-W487 HydrophobicContact CZ-CB 3.43Å; F444-W487 VanDerWaalsContact CZ-CB 3.43Å; F444-W487 HydrophobicContact CZ-CE3 4.25Å; F444-W487 HydrophobicContact CZ-CG 4.44Å; F444-L488 HydrophobicContact CD1-CD2 3.97Å; F444-L488 HydrophobicContact CD1-CG 4.46Å; F444-L488 HydrophobicContact CE1-CD2 3.77Å; F444-L488 HydrophobicContact CE1-CG 3.84Å; F444-F491 HydrophobicContact CB-CB 4.16Å; F444-F491 HydrophobicContact CB-CD1 3.63Å; F444-F491 HydrophobicContact CB-CD2 3.78Å; F444-F491 HydrophobicContact CB-CE1 3.86Å; F444-F491 HydrophobicContact CB-CE2 4.02Å; F444-F491 HydrophobicContact CB-CG 3.57Å; F444-F491 HydrophobicContact CB-CZ 4.05Å; F444-F491 HydrophobicContact CD1-CB 4.39Å; F444-F491 HydrophobicContact CG-CB 4.24Å; F444-F491 HydrophobicContact CG-CD1 4.47Å; F444-F491 HydrophobicContact CG-CG 4.18Å
445L98.6Very high91.5Very high0 Ų026.7 Ų26.70%015%0.145CC..EExtended strand (participates in β ladder)trans-134.1142.1-175.5-59.3117.2000110.8I391 F414 I420 D422 A423 L443 Y461 I462I391-L445 HydrophobicContact CD1-CD2 3.73Å; F414-L445 HydrophobicContact CB-CD1 4.14Å; F414-L445 HydrophobicContact CB-CD2 4.19Å; F414-L445 HydrophobicContact CD1-CD1 4.17Å; F414-L445 HydrophobicContact CD1-CD2 3.28Å; F414-L445 HydrophobicContact CD1-CG 4.32Å; F414-L445 HydrophobicContact CD2-CD1 3.66Å; F414-L445 HydrophobicContact CD2-CD2 4.32Å; F414-L445 HydrophobicContact CE1-CD1 4.46Å; F414-L445 HydrophobicContact CE1-CD2 3.55Å; F414-L445 HydrophobicContact CE1-CG 4.47Å; F414-L445 HydrophobicContact CE2-CD1 4Å; F414-L445 HydrophobicContact CG-CD1 3.72Å; F414-L445 HydrophobicContact CG-CD2 3.67Å; F414-L445 HydrophobicContact CG-CG 4.35Å; F414-L445 HydrophobicContact CZ-CD1 4.36Å; F414-L445 HydrophobicContact CZ-CD2 4.17Å; I420-L445 HydrophobicContact CD1-CD2 4.19Å; I420-L445 HydrophobicContact CG2-CD2 4.19Å; D422-L445 WeakPolarHBondContact O-CA 3.48Å; A423-L445 HydrophobicContact CB-CD2 4.44Å; L443-L445 HydrophobicContact CD2-CD1 3.9Å; L443-L445 HydrophobicContact CD2-CG 4.44Å; L443-L445 HydrophobicContact CG-CD1 3.88Å; L443-L445 HydrophobicContact CG-CG 4.22Å; L445-Y461 WeakPolarHBondContact O-CA 3.49Å; L445-I462 HydrophobicContact CB-CB 4.46Å; L445-I462 PolarHBondContact N-O 3.46Å; L445-I462 PolarHBondContact O-N 3.42Å
446K97.9Very high91.7Very high1 Ų127.3 Ų27.30%0.00415%0.147CC..EExtended strand (participates in β ladder)trans-117.3127.2166.2-173-177.3-179.5-172.50108.5M421 D422 V459 G460 Y461 F491 T495 E505M421-K446 HydrophobicContact CB-CG 4.47Å; M421-K446 PolarHBondContact N-O 2.97Å; M421-K446 HydrophobicContact SD-CD 4.4Å; M421-K446 HydrophobicContact SD-CG 4.35Å; D422-K446 HydrophobicContact CB-CB 4.04Å; D422-K446 PolarHBondContact N-O 3.36Å; D422-K446 PolarHBondContact O-N 3.18Å; K446-V459 HydrophobicContact CG-CB 4.45Å; K446-G460 WeakPolarHBondContact CA-O 3.45Å; K446-Y461 HydrophobicContact CB-CD1 4.32Å; K446-Y461 HydrophobicContact CB-CE1 4.07Å; K446-Y461 HydrophobicContact CD-CE1 4.06Å; K446-Y461 HydrophobicContact CG-CD1 4.42Å; K446-Y461 HydrophobicContact CG-CE1 3.95Å; K446-F491 HydrophobicContact CB-CE1 4.23Å; K446-F491 HydrophobicContact CB-CZ 4.31Å; K446-T495 PolarHBondContact NZ-O 3.12Å; K446-E505 IonicContact NZ-OE1 2.93Å; K446-E505 PolarHBondContact NZ-OE1 3.31Å; K446-E505 IonicContact NZ-OE2 2.68Å; K446-E505 PolarHBondContact NZ-OE2 2.81Å
447V96.6Very high92Very high0 Ų028.8 Ų28.80%015%0.148CC..EExtended strand (participates in β ladder)trans-119.5146.4-178-68.10000110.9F364 F414 P419 I420 V449 V459 G460 I462 F509F364-V447 HydrophobicContact CE1-CB 4.21Å; F364-V447 HydrophobicContact CE1-CG1 4.12Å; F364-V447 HydrophobicContact CE1-CG2 3.78Å; F364-V447 HydrophobicContact CZ-CG2 3.96Å; F414-V447 HydrophobicContact CE1-CG1 4.5Å; F414-V447 HydrophobicContact CZ-CG1 4.34Å; P419-V447 CarbonylContact O-C 3.6Å; P419-V447 WeakPolarHBondContact O-CA 3.42Å; I420-V447 HydrophobicContact CG1-CG1 4.25Å; V447-V449 HydrophobicContact CG2-CG1 3.92Å; V447-V459 CarbonylContact O-C 3.59Å; V447-V459 WeakPolarHBondContact O-CA 3.31Å; V447-G460 WeakPolarHBondContact CG2-O 3.45Å; V447-G460 PolarHBondContact N-O 2.81Å; V447-G460 PolarHBondContact O-N 2.9Å; V447-I462 HydrophobicContact CG2-CD1 4.19Å; V447-F509 HydrophobicContact CG2-CE2 4.24Å; V447-F509 HydrophobicContact CG2-CZ 4.01Å
448Q94.9Very high92.3Very high51 Ų5125.1 Ų25.124%0.23813%0.129CC..EExtended strand (participates in β ladder)trans-94118.5170.9178.4173.5-20.100109.4P419 M421 R457P419-Q448 WeakPolarHBondContact CD-O 3.36Å; P419-Q448 PolarHBondContact O-N 3.25Å; M421-Q448 HydrophobicContact CG-CB 4.02Å; M421-Q448 HydrophobicContact SD-CB 3.81Å; Q448-R457 HydrophobicContact CG-CG 3.78Å
449V93.9Very high92.6Very high3 Ų324.7 Ų24.72%0.01813%0.125CC..EExtended strand (participates in β ladder)trans-109.5-9.8-173.9-62.80000114.6W115 F124 F364 Y418 V447 I458 A508 F509W115-V449 HydrophobicContact CE3-CG2 4.27Å; W115-V449 HydrophobicContact CZ3-CG2 4.34Å; F124-V449 HydrophobicContact CE1-CB 3.65Å; F124-V449 HydrophobicContact CE1-CG1 3.9Å; F124-V449 HydrophobicContact CE1-CG2 4.18Å; F124-V449 HydrophobicContact CZ-CB 3.79Å; F124-V449 HydrophobicContact CZ-CG1 4.36Å; F124-V449 HydrophobicContact CZ-CG2 3.8Å; F364-V449 HydrophobicContact CZ-CG1 3.95Å; Y418-V449 HydrophobicContact CD1-CB 4.15Å; Y418-V449 HydrophobicContact CD1-CG1 4.17Å; Y418-V449 HydrophobicContact CD2-CG1 4.43Å; Y418-V449 HydrophobicContact CE1-CB 4.24Å; Y418-V449 WeakPolarHBondContact CE1-O 2.86Å; Y418-V449 HydrophobicContact CG-CG1 4.06Å; V447-V449 HydrophobicContact CG2-CG1 3.92Å; V449-I458 HydrophobicContact CG2-CB 4.09Å; V449-I458 HydrophobicContact CG2-CG2 3.62Å; V449-I458 PolarHBondContact N-O 3Å; V449-A508 HydrophobicContact CG2-CB 4.21Å; V449-F509 HydrophobicContact CG1-CE1 3.9Å; V449-F509 HydrophobicContact CG1-CZ 3.81Å; V449-F509 HydrophobicContact CG2-CE1 4.4Å
450G91.5Very high92.9Very high1 Ų124.7 Ų24.71%0.0113%0.125CC..EExtended strand (participates in β ladder)trans173.7-166.4178.500000113W115 I458W115-G450 CarbonylContact O-C 3.54Å; W115-G450 WeakPolarHBondContact O-CA 3.47Å; G450-I458 PolarHBondContact N-O 2.87Å; G450-I458 PolarHBondContact O-N 2.98Å
451S89.5Confident93.1Very high8 Ų824.4 Ų24.46%0.05612%0.124CC..EExtended strand (participates in β ladder)trans-140.8155.8172.2770000109.9W115 K116 Q456W115-S451 PolarHBondContact O-N 2.88Å; K116-S451 CarbonylContact C-O 3.4Å; K116-S451 WeakPolarHBondContact CA-O 3.1Å; K116-S451 WeakPolarHBondContact CD-OG 3.31Å; K116-S451 PolarHBondContact NZ-OG 3.48Å; S451-Q456 CarbonylContact C-O 3.57Å; S451-Q456 WeakPolarHBondContact CA-O 3.39Å
452T87.1Confident93.2Very high7 Ų724.5 Ų24.54%0.04312%0.124CC..  trans-81.8170.8169.468.30000110.8A117 Q454 D455 Q456 I458 L506A117-T452 HydrophobicContact CB-CG2 4.46Å; T452-Q454 PolarHBondContact O-N 3.39Å; T452-Q454 PolarHBondContact OG1-N 3.05Å; T452-Q454 PolarHBondContact OG1-OE1 2.63Å; T452-D455 PolarHBondContact O-N 2.91Å; T452-Q456 HydrophobicContact CG2-CB 4.01Å; T452-Q456 PolarHBondContact N-O 2.8Å; T452-Q456 VanDerWaalsContact OG1-CB 3.3Å; T452-Q456 WeakPolarHBondContact OG1-CB 3.09Å; T452-Q456 PolarHBondContact OG1-N 3.06Å; T452-Q456 VanDerWaalsContact OG1-N 3.11Å; T452-Q456 PolarHBondContact OG1-OE1 2.86Å; T452-I458 HydrophobicContact CG2-CD1 4.34Å; T452-I458 HydrophobicContact CG2-CG1 4.21Å; T452-L506 HydrophobicContact CG2-CD1 3.41Å; T452-L506 VanDerWaalsContact CG2-CD1 3.41Å; T452-L506 HydrophobicContact CG2-CG 4.37Å
453P84Confident93.3Very high78 Ų7824.6 Ų24.651%0.50613%0.125SC..THydrogen-bonded Turntrans-62.1-19169.9-23.537.2000113.4K116 A118 D455K116-P453 WeakPolarHBondContact O-CD 3.49Å; A118-P453 HydrophobicContact CB-CG 4.01Å; P453-D455 VanDerWaalsContact C-N 3.29Å
454Q84.7Confident93.2Very high137 Ų13724.6 Ų24.664%0.6413%0.125SC*.THydrogen-bonded Turntrans-91.515.1175.1-59.177.215.500112.5T452 Q456T452-Q454 PolarHBondContact O-N 3.39Å; T452-Q454 PolarHBondContact OG1-N 3.05Å; T452-Q454 PolarHBondContact OG1-OE1 2.63Å; Q454-Q456 PolarHBondContact O-N 2.82Å; Q454-Q456 VanDerWaalsContact O-N 3.17Å
455D83.8Confident93.2Very high124 Ų12424.7 Ų24.766%0.66313%0.125SC*.  trans58.422.5-178.1-67.8-34.3000114.7T452 P453T452-D455 PolarHBondContact O-N 2.91Å; P453-D455 VanDerWaalsContact C-N 3.29Å
456Q87.6Confident93.2Very high35 Ų3524.7 Ų24.716%0.16413%0.125CC..PPolyproline II helixtrans-74141.5168.6-60.4165.1-60.600109.1S451 T452 Q454 E504 L506S451-Q456 CarbonylContact C-O 3.57Å; S451-Q456 WeakPolarHBondContact CA-O 3.39Å; T452-Q456 HydrophobicContact CG2-CB 4.01Å; T452-Q456 PolarHBondContact N-O 2.8Å; T452-Q456 VanDerWaalsContact OG1-CB 3.3Å; T452-Q456 WeakPolarHBondContact OG1-CB 3.09Å; T452-Q456 PolarHBondContact OG1-N 3.06Å; T452-Q456 VanDerWaalsContact OG1-N 3.11Å; T452-Q456 PolarHBondContact OG1-OE1 2.86Å; Q454-Q456 PolarHBondContact O-N 2.82Å; Q454-Q456 VanDerWaalsContact O-N 3.17Å; Q456-E504 WeakPolarHBondContact CB-O 3.4Å; Q456-E504 HydrophobicContact CG-CB 4.22Å; Q456-E504 PolarHBondContact NE2-OE2 3.38Å; Q456-L506 HydrophobicContact CB-CG 4.34Å
457R90.4Very high93.2Very high63 Ų6324.6 Ų24.624%0.23813%0.125CC..EExtended strand (participates in β ladder)trans-82133.8-177.3-174.2-177.7-72.9138.3-0.2109.8M421 Q448 V459 E504 E505 L506M421-R457 VanDerWaalsContact CE-CD 3.47Å; Q448-R457 HydrophobicContact CG-CG 3.78Å; R457-V459 HydrophobicContact CG-CG1 3.81Å; R457-E504 PolarHBondContact N-O 2.96Å; R457-E505 HydrophobicContact CB-CG 4.49Å; R457-E505 IonicContact NH1-OE1 3.74Å; R457-E505 CarbonylContact O-C 3.55Å; R457-E505 WeakPolarHBondContact O-CA 3.29Å; R457-L506 PolarHBondContact O-N 2.73Å
458I92.7Very high93.1Very high0 Ų024.7 Ų24.70%013%0.125CC..EExtended strand (participates in β ladder)trans-98.4124.5172.7-47.8173.5000108.9W115 A117 V449 G450 T452 L506 A508 W627W115-I458 HydrophobicContact CD2-CD1 4.16Å; W115-I458 HydrophobicContact CE3-CD1 3.85Å; W115-I458 HydrophobicContact CE3-CG2 4.06Å; W115-I458 HydrophobicContact CH2-CG2 4.48Å; W115-I458 HydrophobicContact CZ3-CD1 4.11Å; W115-I458 HydrophobicContact CZ3-CG2 3.64Å; A117-I458 HydrophobicContact CB-CD1 3.61Å; V449-I458 HydrophobicContact CG2-CB 4.09Å; V449-I458 HydrophobicContact CG2-CG2 3.62Å; V449-I458 PolarHBondContact N-O 3Å; G450-I458 PolarHBondContact N-O 2.87Å; G450-I458 PolarHBondContact O-N 2.98Å; T452-I458 HydrophobicContact CG2-CD1 4.34Å; T452-I458 HydrophobicContact CG2-CG1 4.21Å; I458-L506 CarbonylContact C-O 3.54Å; I458-L506 WeakPolarHBondContact CA-O 3.48Å; I458-A508 HydrophobicContact CG2-CB 3.84Å; I458-W627 HydrophobicContact CB-CH2 4.3Å; I458-W627 HydrophobicContact CD1-CH2 3.77Å; I458-W627 HydrophobicContact CD1-CZ2 4.42Å; I458-W627 HydrophobicContact CG1-CH2 3.84Å; I458-W627 HydrophobicContact CG2-CH2 3.51Å; I458-W627 HydrophobicContact CG2-CZ3 3.53Å
459V95.1Very high92.9Very high0 Ų024.1 Ų24.10%013%0.129CC..EExtended strand (participates in β ladder)trans-124.8158.5-174.5-56.50000111.7M421 K446 V447 R457 E505 L506 V507 A508M421-V459 HydrophobicContact SD-CG1 3.73Å; K446-V459 HydrophobicContact CG-CB 4.45Å; V447-V459 CarbonylContact O-C 3.59Å; V447-V459 WeakPolarHBondContact O-CA 3.31Å; R457-V459 HydrophobicContact CG-CG1 3.81Å; V459-E505 HydrophobicContact CG1-CG 4.49Å; V459-E505 HydrophobicContact CG2-CB 4.31Å; V459-L506 PolarHBondContact N-O 2.91Å; V459-V507 HydrophobicContact CG2-CG2 4.03Å; V459-V507 CarbonylContact O-C 3.55Å; V459-V507 WeakPolarHBondContact O-CA 3.36Å; V459-A508 PolarHBondContact O-N 3Å
460G96.7Very high92Very high0 Ų026.9 Ų26.90%014%0.143CC..EExtended strand (participates in β ladder)trans-137.2150.5171.700000111.5K446 V447 F509K446-G460 WeakPolarHBondContact CA-O 3.45Å; V447-G460 WeakPolarHBondContact CG2-O 3.45Å; V447-G460 PolarHBondContact N-O 2.81Å; V447-G460 PolarHBondContact O-N 2.9Å; G460-F509 WeakPolarHBondContact CA-O 3.5Å
461Y98.4Very high91.1Very high5 Ų530.4 Ų30.42%0.0217%0.172CC..EExtended strand (participates in β ladder)trans-107.2136.1176.8-70-84.2000110.5L445 K446 F491 R492 T495 V507 F509 D510 V511L445-Y461 WeakPolarHBondContact O-CA 3.49Å; K446-Y461 HydrophobicContact CB-CD1 4.32Å; K446-Y461 HydrophobicContact CB-CE1 4.07Å; K446-Y461 HydrophobicContact CD-CE1 4.06Å; K446-Y461 HydrophobicContact CG-CD1 4.42Å; K446-Y461 HydrophobicContact CG-CE1 3.95Å; Y461-F491 HydrophobicContact CD1-CD1 4.04Å; Y461-F491 AromaticContact CD1-CE1 3.87Å; Y461-F491 HydrophobicContact CD1-CE1 3.87Å; Y461-F491 HydrophobicContact CE1-CD1 4.16Å; Y461-F491 HydrophobicContact CE1-CE1 4Å; Y461-R492 HydrophobicContact CE2-CG 4.33Å; Y461-T495 WeakPolarHBondContact CE1-OG1 3.25Å; Y461-T495 PolarHBondContact OH-OG1 3Å; Y461-V507 HydrophobicContact CD2-CG1 3.85Å; Y461-V507 HydrophobicContact CE2-CG1 4.12Å; Y461-V507 HydrophobicContact CE2-CG2 3.97Å; Y461-F509 PolarHBondContact N-O 3.03Å; Y461-D510 WeakPolarHBondContact O-CA 3.43Å; Y461-V511 PolarHBondContact O-N 2.81Å
462I98.8Very high90.2Very high1 Ų132.5 Ų32.51%0.00520%0.196CC..EExtended strand (participates in β ladder)trans-137.7132.4178.7-54.1167.8000108.5F126 F364 F414 L445 V447 F509 V511F126-I462 HydrophobicContact CD1-CD1 4.36Å; F126-I462 HydrophobicContact CE1-CD1 3.97Å; F126-I462 HydrophobicContact CE1-CG1 4.06Å; F364-I462 HydrophobicContact CB-CD1 3.86Å; F364-I462 HydrophobicContact CD1-CD1 3.31Å; F364-I462 HydrophobicContact CD2-CD1 3.9Å; F364-I462 HydrophobicContact CE1-CD1 3.74Å; F364-I462 HydrophobicContact CE2-CD1 4.28Å; F364-I462 HydrophobicContact CG-CD1 3.39Å; F364-I462 HydrophobicContact CZ-CD1 4.22Å; F414-I462 HydrophobicContact CE2-CB 4.37Å; F414-I462 HydrophobicContact CE2-CD1 3.87Å; F414-I462 HydrophobicContact CE2-CG2 3.99Å; F414-I462 HydrophobicContact CZ-CD1 3.83Å; L445-I462 HydrophobicContact CB-CB 4.46Å; L445-I462 PolarHBondContact N-O 3.46Å; L445-I462 PolarHBondContact O-N 3.42Å; V447-I462 HydrophobicContact CG2-CD1 4.19Å; I462-F509 HydrophobicContact CD1-CE2 4.09Å; I462-F509 HydrophobicContact CG1-CE2 3.87Å; I462-V511 CarbonylContact C-O 3.51Å; I462-V511 WeakPolarHBondContact CA-O 3.4Å
463S98.6Very high90.1Very high3 Ų333.4 Ų33.42%0.02120%0.2CC..EExtended strand (participates in β ladder)trans-127.2128.6176.4-55.90000111.2L443 F444 L488 V511 I512 C513L443-S463 CarbonylContact O-C 3.56Å; L443-S463 VanDerWaalsContact O-CA 3.26Å; L443-S463 WeakPolarHBondContact O-CA 3.42Å; F444-S463 VanDerWaalsContact CD1-OG 3.26Å; F444-S463 WeakPolarHBondContact CD1-OG 3.13Å; S463-L488 WeakPolarHBondContact OG-CD2 2.95Å; S463-V511 PolarHBondContact N-O 2.78Å; S463-I512 CarbonylContact O-C 3.38Å; S463-I512 WeakPolarHBondContact O-CA 3.33Å; S463-C513 PolarHBondContact O-N 2.85Å
464C98.4Very high90.3Very high0 Ų030.5 Ų30.50%018%0.181CC..EExtended strand (participates in β ladder)trans-116.4129.3177.6176.70000109.6C366 Q368 A442 L443 C513C366-C464 HydrophobicContact CB-CB 3.89Å; Q368-C464 PolarHBondContact NE2-SG 3.23Å; A442-C464 CarbonylContact C-O 3.54Å; A442-C464 WeakPolarHBondContact CA-O 3.29Å; L443-C464 PolarHBondContact N-O 2.91Å; L443-C464 PolarHBondContact O-N 3.23Å; C464-C513 VanDerWaalsContact CA-O 3.31Å; C464-C513 WeakPolarHBondContact CA-O 3.34Å
465T98.6Very high90.7Very high1 Ų127.9 Ų27.91%0.00617%0.174CC..EExtended strand (participates in β ladder)trans-134.1158.3-178.7-173.20000112.3Y428 G441 L467 L484 C513 G514 D515 L516Y428-T465 PolarHBondContact OH-OG1 3.47Å; G441-T465 WeakPolarHBondContact O-CA 3.32Å; G441-T465 PolarHBondContact O-OG1 3.26Å; T465-L467 HydrophobicContact CG2-CD2 4.33Å; T465-L467 WeakPolarHBondContact OG1-CD2 3.28Å; T465-L484 HydrophobicContact CG2-CD2 4.19Å; T465-C513 PolarHBondContact N-O 3.28Å; T465-G514 WeakPolarHBondContact O-CA 3.3Å; T465-D515 PolarHBondContact O-N 3.15Å; T465-L516 HydrophobicContact CG2-CD2 3.49Å; T465-L516 VanDerWaalsContact CG2-CD2 3.49Å
466H98.1Very high91.2Very high0 Ų022.1 Ų22.10%014%0.144CC..EExtended strand (participates in β ladder)trans-135.4110.5167.9-175.6-177.6000108.7Q368 E369 L412 K440 G441 D515 N517Q368-H466 HydrophobicContact CG-CB 4.26Å; E369-H466 IonicContact OE1-CE1 2.93Å; E369-H466 PolarHBondContact OE1-CE1 3.26Å; L412-H466 HydrophobicContact CD2-CB 4.05Å; K440-H466 VanDerWaalsContact CE-CE1 3.49Å; K440-H466 WeakPolarHBondContact CE-CE1 3.48Å; K440-H466 WeakPolarHBondContact CE-NE2 3.41Å; K440-H466 PolarHBondContact NZ-CD2 3.12Å; K440-H466 PolarHBondContact NZ-CE1 3.43Å; K440-H466 PolarHBondContact NZ-NE2 3.48Å; G441-H466 PolarHBondContact O-N 3.2Å; H466-D515 WeakPolarHBondContact CA-O 3.42Å; H466-D515 IonicContact NE2-OD2 3.17Å; H466-N517 PolarHBondContact CD2-ND2 3.25Å; H466-N517 VanDerWaalsContact CD2-ND2 3.34Å; H466-N517 PolarHBondContact NE2-ND2 3.09Å; H466-N517 VanDerWaalsContact NE2-ND2 3.2Å
467L97.3Very high91.7Very high0 Ų020.5 Ų20.50%014%0.136CC..  trans-84.8173.3-175.9-56.7-168000112.9Y428 K440 T465 A469 R477 Q480 L481 D515 L516 N517 F518Y428-L467 HydrophobicContact CD2-CD2 4.47Å; Y428-L467 HydrophobicContact CE2-CD2 3.54Å; K440-L467 WeakPolarHBondContact CD-O 3.47Å; K440-L467 PolarHBondContact NZ-O 3.05Å; T465-L467 HydrophobicContact CG2-CD2 4.33Å; T465-L467 WeakPolarHBondContact OG1-CD2 3.28Å; L467-A469 PolarHBondContact O-N 3.4Å; L467-R477 HydrophobicContact CB-CG 4.41Å; L467-Q480 HydrophobicContact CD2-CB 3.96Å; L467-L481 HydrophobicContact CD1-CD2 3.83Å; L467-L481 HydrophobicContact CD1-CG 4.01Å; L467-D515 PolarHBondContact N-O 3.3Å; L467-L516 HydrophobicContact CD1-CB 4.01Å; L467-L516 HydrophobicContact CD1-CD2 3.92Å; L467-L516 HydrophobicContact CD1-CG 4.49Å; L467-L516 HydrophobicContact CG-CB 4.44Å; L467-L516 HydrophobicContact CG-CD2 3.97Å; L467-N517 PolarHBondContact O-ND2 3.12Å; L467-N517 VanDerWaalsContact O-ND2 3.16Å; L467-F518 HydrophobicContact CD1-CE1 4.26Å
468Q95.2Very high92Very high1 Ų118.6 Ų18.61%0.00513%0.132CC..  trans-54.5124.6175.8177.86734.700112.3K432 I470 D473 V476 R477 N517K432-Q468 PolarHBondContact O-NE2 3.04Å; K432-Q468 VanDerWaalsContact O-NE2 3.11Å; Q468-I470 VanDerWaalsContact NE2-CD1 3.35Å; Q468-I470 VanDerWaalsContact NE2-CG1 3.3Å; Q468-D473 HydrophobicContact CG-CB 4.07Å; Q468-V476 HydrophobicContact CB-CB 4.47Å; Q468-V476 HydrophobicContact CB-CG1 3.8Å; Q468-V476 HydrophobicContact CG-CB 4.33Å; Q468-V476 HydrophobicContact CG-CG1 3.91Å; Q468-R477 HydrophobicContact CB-CG 4.09Å; Q468-R477 PolarHBondContact O-NH1 3Å; Q468-N517 VanDerWaalsContact O-CB 3.26Å; Q468-N517 WeakPolarHBondContact O-CB 3.32Å
469A89.4Confident92.2Very high39 Ų3923 Ų2332%0.32215%0.153SC..  trans-85.9-23.2-173.300000114.9D435 L467 A471 N517D435-A469 WeakPolarHBondContact OD2-CB 3.23Å; D435-A469 PolarHBondContact OD2-N 3.17Å; L467-A469 PolarHBondContact O-N 3.4Å; A469-A471 PolarHBondContact O-N 2.92Å; A469-A471 VanDerWaalsContact O-N 3.12Å; A469-N517 VanDerWaalsContact CA-CG 3.49Å
470I76.8Confident92.4Very high61 Ų6123 Ų2331%0.31315%0.153SC..SBendtrans-61.1120.8-176.2-63.9176.1000110.1K432 Q468 G472 D473 R477K432-I470 HydrophobicContact CB-CD1 4.44Å; Q468-I470 VanDerWaalsContact NE2-CD1 3.35Å; Q468-I470 VanDerWaalsContact NE2-CG1 3.3Å; I470-G472 PolarHBondContact O-N 3.37Å; I470-D473 HydrophobicContact CB-CB 4.36Å; I470-D473 WeakPolarHBondContact CB-OD2 3.26Å; I470-D473 HydrophobicContact CG2-CB 4.49Å; I470-D473 WeakPolarHBondContact CG2-OD2 3.28Å; I470-D473 PolarHBondContact O-N 2.97Å; I470-R477 PolarHBondContact O-NH1 2.86Å
471A71.9Confident92.4Very high75 Ų7523 Ų2362%0.6215%0.153SC*.THydrogen-bonded Turntrans-60.6132.8175.300000110.5A469A469-A471 PolarHBondContact O-N 2.92Å; A469-A471 VanDerWaalsContact O-N 3.12Å
472G70.4Confident92.4Very high53 Ų5326.4 Ų26.455%0.54617%0.171SC..THydrogen-bonded Turntrans86.7-6.2-178.800000115.8I470 T474I470-G472 PolarHBondContact O-N 3.37Å; G472-T474 PolarHBondContact O-N 3.47Å
473D85Confident92.4Very high26 Ų2628.1 Ų28.114%0.13918%0.18CC..  trans-80.444.9170.9-90.6-34.1000112.4K432 Q468 I470 T475 V476 R477K432-D473 WeakPolarHBondContact CD-OD1 3.45Å; K432-D473 WeakPolarHBondContact CD-OD2 3.38Å; K432-D473 IonicContact NZ-OD1 3.64Å; K432-D473 PolarHBondContact NZ-OD1 3.43Å; Q468-D473 HydrophobicContact CG-CB 4.07Å; I470-D473 HydrophobicContact CB-CB 4.36Å; I470-D473 WeakPolarHBondContact CB-OD2 3.26Å; I470-D473 HydrophobicContact CG2-CB 4.49Å; I470-D473 WeakPolarHBondContact CG2-OD2 3.28Å; I470-D473 PolarHBondContact O-N 2.97Å; D473-T475 VanDerWaalsContact C-N 3.3Å; D473-T475 PolarHBondContact O-N 2.85Å; D473-V476 HydrophobicContact CB-CB 4.36Å; D473-V476 HydrophobicContact CB-CG2 4.23Å; D473-V476 WeakPolarHBondContact O-CB 3.17Å; D473-V476 PolarHBondContact O-N 3.27Å; D473-V476 VanDerWaalsContact O-N 3.08Å; D473-R477 PolarHBondContact O-N 3.21Å
474T88.4Confident92.4Very high16 Ų1628 Ų2810%0.09818%0.179CC..Hα-helixtrans-54.5-42.1-176.7-69.90000113.7G472 V476 R477 C478 E524 L527 E528G472-T474 PolarHBondContact O-N 3.47Å; T474-V476 VanDerWaalsContact C-N 3.26Å; T474-V476 PolarHBondContact O-N 3.38Å; T474-R477 PolarHBondContact O-N 2.73Å; T474-C478 PolarHBondContact O-N 2.95Å; T474-C478 PolarHBondContact O-SG 3.3Å; T474-C478 VanDerWaalsContact O-SG 3.4Å; T474-E524 PolarHBondContact OG1-O 2.84Å; T474-L527 HydrophobicContact CG2-CB 3.55Å; T474-L527 HydrophobicContact CG2-CD1 3.7Å; T474-L527 HydrophobicContact CG2-CG 3.9Å; T474-E528 WeakPolarHBondContact CA-OE1 3.49Å; T474-E528 WeakPolarHBondContact CB-OE1 3.41Å; T474-E528 VanDerWaalsContact CG2-CD 3.41Å; T474-E528 HydrophobicContact CG2-CG 4.4Å; T474-E528 WeakPolarHBondContact CG2-OE2 3.38Å; T474-E528 PolarHBondContact OG1-OE1 2.89Å; T474-E528 PolarHBondContact OG1-OE2 3.5Å
475T92.9Very high92.4Very high82 Ų8229.6 Ų29.650%0.50319%0.186SC..Hα-helixtrans-62.6-36.7-179.161.70000111.8D473 C478 E479D473-T475 VanDerWaalsContact C-N 3.3Å; D473-T475 PolarHBondContact O-N 2.85Å; T475-C478 PolarHBondContact O-N 3.28Å; T475-E479 WeakPolarHBondContact O-CG 3.44Å; T475-E479 PolarHBondContact O-N 3.36Å
476V94.6Very high92.4Very high4 Ų434.7 Ų34.72%0.02421%0.214CC..Hα-helixtrans-65.3-45.6177.4178.30000109.7N430 K432 Q468 D473 T474 E479 Q480N430-V476 PolarHBondContact ND2-O 2.9Å; N430-V476 WeakPolarHBondContact O-CG1 3.1Å; K432-V476 HydrophobicContact CD-CG2 3.86Å; K432-V476 VanDerWaalsContact CE-CG2 3.42Å; K432-V476 HydrophobicContact CG-CG2 4.24Å; Q468-V476 HydrophobicContact CB-CB 4.47Å; Q468-V476 HydrophobicContact CB-CG1 3.8Å; Q468-V476 HydrophobicContact CG-CB 4.33Å; Q468-V476 HydrophobicContact CG-CG1 3.91Å; D473-V476 HydrophobicContact CB-CB 4.36Å; D473-V476 HydrophobicContact CB-CG2 4.23Å; D473-V476 WeakPolarHBondContact O-CB 3.17Å; D473-V476 PolarHBondContact O-N 3.27Å; D473-V476 VanDerWaalsContact O-N 3.08Å; T474-V476 VanDerWaalsContact C-N 3.26Å; T474-V476 PolarHBondContact O-N 3.38Å; V476-E479 PolarHBondContact O-N 2.93Å; V476-Q480 HydrophobicContact CG1-CG 4.47Å; V476-Q480 WeakPolarHBondContact O-CG 3.25Å; V476-Q480 PolarHBondContact O-N 3.3Å
477R97.1Very high92.4Very high1 Ų136.5 Ų36.50%0.00422%0.221CC..Hα-helixtrans-64.6-40.8178-72.2-170.2-67.3-102.76.4112.3L467 Q468 I470 D473 T474 Q480 L481 L516 N517 D525 E528L467-R477 HydrophobicContact CB-CG 4.41Å; Q468-R477 HydrophobicContact CB-CG 4.09Å; Q468-R477 PolarHBondContact O-NH1 3Å; I470-R477 PolarHBondContact O-NH1 2.86Å; D473-R477 PolarHBondContact O-N 3.21Å; T474-R477 PolarHBondContact O-N 2.73Å; R477-Q480 PolarHBondContact O-N 2.99Å; R477-L481 VanDerWaalsContact O-CG 3.28Å; R477-L481 WeakPolarHBondContact O-CG 3.17Å; R477-L481 PolarHBondContact O-N 2.86Å; R477-L516 WeakPolarHBondContact CD-O 3.25Å; R477-N517 PolarHBondContact NH1-O 3.39Å; R477-D525 IonicContact CZ-OD1 2.6Å; R477-D525 IonicContact NH2-OD1 3.28Å; R477-D525 PolarHBondContact NH2-OD1 3.2Å; R477-E528 HydrophobicContact CB-CG 3.88Å; R477-E528 IonicContact CZ-OE1 2.82Å; R477-E528 IonicContact NE-OE1 2.86Å; R477-E528 PolarHBondContact NE-OE1 2.85Å; R477-E528 IonicContact NH2-OE1 2.8Å; R477-E528 PolarHBondContact NH2-OE1 3.09Å
478C97.7Very high92.4Very high22 Ų2237.2 Ų37.215%0.14922%0.224CC..Hα-helixtrans-59-49.8173.5-67.90000111.7T474 T475 Q480 L481 D482 H531T474-C478 PolarHBondContact O-N 2.95Å; T474-C478 PolarHBondContact O-SG 3.3Å; T474-C478 VanDerWaalsContact O-SG 3.4Å; T475-C478 PolarHBondContact O-N 3.28Å; C478-Q480 PolarHBondContact O-N 3.08Å; C478-L481 WeakPolarHBondContact O-CB 3.13Å; C478-L481 PolarHBondContact O-N 3.38Å; C478-D482 PolarHBondContact O-N 3.25Å; C478-H531 PolarHBondContact O-NE2 2.96Å
479E97.3Very high92.3Very high94 Ų9441.1 Ų41.144%0.43925%0.251SS..Hα-helixtrans-59.7-35.7176.1-72.4170.3-169.800112.4N430 T475 V476 D482 M483N430-E479 WeakPolarHBondContact ND2-CB 3.48Å; N430-E479 PolarHBondContact ND2-OE2 3.22Å; T475-E479 WeakPolarHBondContact O-CG 3.44Å; T475-E479 PolarHBondContact O-N 3.36Å; V476-E479 PolarHBondContact O-N 2.93Å; E479-D482 PolarHBondContact O-N 2.95Å; E479-M483 HydrophobicContact CB-CE 4.34Å; E479-M483 VanDerWaalsContact O-CE 3.26Å; E479-M483 WeakPolarHBondContact O-CE 3.45Å; E479-M483 WeakPolarHBondContact O-CG 3.49Å; E479-M483 PolarHBondContact O-N 3.36Å
480Q97.9Very high92.7Very high0 Ų044.7 Ų44.70%026%0.262CS..Hα-helixtrans-68.2-37174.5-69.8175.5-8.700112.6Y428 N430 L467 V476 R477 C478 M483 L484Y428-Q480 HydrophobicContact CD1-CB 3.88Å; Y428-Q480 HydrophobicContact CD1-CG 3.67Å; Y428-Q480 HydrophobicContact CD2-CB 4.37Å; Y428-Q480 HydrophobicContact CD2-CG 3.98Å; Y428-Q480 HydrophobicContact CE1-CB 3.79Å; Y428-Q480 HydrophobicContact CE1-CG 4.13Å; Y428-Q480 WeakPolarHBondContact CE1-O 3.46Å; Y428-Q480 HydrophobicContact CE2-CB 4.33Å; Y428-Q480 HydrophobicContact CE2-CG 4.44Å; Y428-Q480 HydrophobicContact CG-CB 4.18Å; Y428-Q480 HydrophobicContact CG-CG 3.6Å; N430-Q480 WeakPolarHBondContact OD1-CG 3.21Å; N430-Q480 PolarHBondContact OD1-NE2 3.22Å; L467-Q480 HydrophobicContact CD2-CB 3.96Å; V476-Q480 HydrophobicContact CG1-CG 4.47Å; V476-Q480 WeakPolarHBondContact O-CG 3.25Å; V476-Q480 PolarHBondContact O-N 3.3Å; R477-Q480 PolarHBondContact O-N 2.99Å; C478-Q480 PolarHBondContact O-N 3.08Å; Q480-M483 HydrophobicContact CG-CE 4.16Å; Q480-M483 PolarHBondContact O-N 3.45Å; Q480-L484 WeakPolarHBondContact O-CB 3.43Å; Q480-L484 PolarHBondContact O-N 2.96Å
481L98.6Very high93.6Very high0 Ų042.2 Ų42.20%025%0.248CC..Hα-helixtrans-68.7-36.7174.2-69166.8000111.8L467 R477 C478 L484 Q485 F518 E528 H531 L533L467-L481 HydrophobicContact CD1-CD2 3.83Å; L467-L481 HydrophobicContact CD1-CG 4.01Å; R477-L481 VanDerWaalsContact O-CG 3.28Å; R477-L481 WeakPolarHBondContact O-CG 3.17Å; R477-L481 PolarHBondContact O-N 2.86Å; C478-L481 WeakPolarHBondContact O-CB 3.13Å; C478-L481 PolarHBondContact O-N 3.38Å; L481-L484 HydrophobicContact CD2-CD2 4.47Å; L481-L484 PolarHBondContact O-N 2.91Å; L481-Q485 WeakPolarHBondContact O-CG 3.17Å; L481-Q485 PolarHBondContact O-N 3.39Å; L481-Q485 VanDerWaalsContact O-N 3.1Å; L481-F518 HydrophobicContact CD1-CE1 3.82Å; L481-F518 HydrophobicContact CD1-CZ 4.18Å; L481-F518 HydrophobicContact CD2-CE1 4.28Å; L481-E528 HydrophobicContact CD1-CB 4.25Å; L481-H531 VanDerWaalsContact C-CE1 3.43Å; L481-H531 WeakPolarHBondContact CB-CE1 3.39Å; L481-H531 VanDerWaalsContact CB-NE2 3.33Å; L481-H531 WeakPolarHBondContact CB-NE2 3.22Å; L481-H531 HydrophobicContact CD1-CB 3.97Å; L481-L533 HydrophobicContact CD2-CD2 3.76Å
482D98.3Very high94.6Very high76 Ų7641.7 Ų41.741%0.40623%0.231SC..Hα-helixtrans-60.4-51.6171.5-70.2-41.4000110.2C478 E479 L484 Q485 D486 H531C478-D482 PolarHBondContact O-N 3.25Å; E479-D482 PolarHBondContact O-N 2.95Å; D482-L484 VanDerWaalsContact C-N 3.29Å; D482-L484 PolarHBondContact O-N 3.33Å; D482-Q485 WeakPolarHBondContact O-CB 3.43Å; D482-Q485 PolarHBondContact O-N 3.04Å; D482-Q485 VanDerWaalsContact O-N 3.16Å; D482-D486 PolarHBondContact O-N 2.78Å; D482-D486 VanDerWaalsContact O-N 3.11Å; D482-H531 PolarHBondContact N-NE2 3.32Å; D482-H531 IonicContact OD1-CE1 2.88Å; D482-H531 IonicContact OD1-NE2 2.68Å; D482-H531 PolarHBondContact OD1-NE2 2.76Å; D482-H531 VanDerWaalsContact OD1-NE2 3.07Å
483M98.4Very high95.7Very high36 Ų3647.6 Ų47.618%0.17724%0.241CC..Hα-helixtrans-58.9-39.9176.4-75.3-176.8-84.300112.4Y428 P429 E479 Q480 Q485 D486 W487Y428-M483 HydrophobicContact CD1-CB 4.35Å; Y428-M483 HydrophobicContact CD1-CE 4.04Å; Y428-M483 HydrophobicContact CD1-SD 4.35Å; Y428-M483 HydrophobicContact CE1-CB 4.19Å; P429-M483 WeakPolarHBondContact CD-SD 3.49Å; P429-M483 HydrophobicContact CG-CE 4.17Å; P429-M483 HydrophobicContact CG-SD 3.85Å; E479-M483 HydrophobicContact CB-CE 4.34Å; E479-M483 VanDerWaalsContact O-CE 3.26Å; E479-M483 WeakPolarHBondContact O-CE 3.45Å; E479-M483 WeakPolarHBondContact O-CG 3.49Å; E479-M483 PolarHBondContact O-N 3.36Å; Q480-M483 HydrophobicContact CG-CE 4.16Å; Q480-M483 PolarHBondContact O-N 3.45Å; M483-Q485 PolarHBondContact O-N 3.23Å; M483-D486 PolarHBondContact O-N 3.5Å; M483-W487 HydrophobicContact CB-CD2 4.33Å; M483-W487 HydrophobicContact CB-CE3 4.3Å; M483-W487 HydrophobicContact CB-CH2 3.95Å; M483-W487 HydrophobicContact CB-CZ2 3.94Å; M483-W487 HydrophobicContact CB-CZ3 4.14Å; M483-W487 HydrophobicContact CG-CH2 4.43Å; M483-W487 HydrophobicContact CG-CZ2 4.19Å; M483-W487 WeakPolarHBondContact O-CB 3.45Å; M483-W487 VanDerWaalsContact O-CD2 3.25Å; M483-W487 PolarHBondContact O-N 3.35Å; M483-W487 HydrophobicContact SD-CH2 3.99Å; M483-W487 HydrophobicContact SD-CZ2 3.96Å
484L98.5Very high96Very high0 Ų049.7 Ų49.70%026%0.258CS..Hα-helixtrans-59.6-45176.6177.661.5000111.3A442 F444 T465 Q480 L481 D482 W487 L488 I512 L533A442-L484 HydrophobicContact CB-CD1 3.82Å; F444-L484 HydrophobicContact CE1-CD1 3.96Å; F444-L484 HydrophobicContact CZ-CD1 3.96Å; T465-L484 HydrophobicContact CG2-CD2 4.19Å; Q480-L484 WeakPolarHBondContact O-CB 3.43Å; Q480-L484 PolarHBondContact O-N 2.96Å; L481-L484 HydrophobicContact CD2-CD2 4.47Å; L481-L484 PolarHBondContact O-N 2.91Å; D482-L484 VanDerWaalsContact C-N 3.29Å; D482-L484 PolarHBondContact O-N 3.33Å; L484-W487 PolarHBondContact O-N 3.19Å; L484-L488 HydrophobicContact CD1-CD1 4.35Å; L484-L488 HydrophobicContact CD1-CG 4.35Å; L484-L488 HydrophobicContact CG-CD1 4.1Å; L484-L488 WeakPolarHBondContact O-CB 3.29Å; L484-L488 WeakPolarHBondContact O-CD1 3.29Å; L484-L488 WeakPolarHBondContact O-CG 3.35Å; L484-L488 PolarHBondContact O-N 2.94Å; L484-I512 HydrophobicContact CD2-CG2 4.31Å; L484-L533 HydrophobicContact CD2-CD2 4.17Å
485Q97.8Very high96.2Very high34 Ų3449.4 Ų49.416%0.15926%0.256CS..Hα-helixtrans-62.1-44.7177-73.91797.600113.3L481 D482 M483 L488 S489 H531 S532 L533L481-Q485 WeakPolarHBondContact O-CG 3.17Å; L481-Q485 PolarHBondContact O-N 3.39Å; L481-Q485 VanDerWaalsContact O-N 3.1Å; D482-Q485 WeakPolarHBondContact O-CB 3.43Å; D482-Q485 PolarHBondContact O-N 3.04Å; D482-Q485 VanDerWaalsContact O-N 3.16Å; M483-Q485 PolarHBondContact O-N 3.23Å; Q485-L488 PolarHBondContact O-N 2.9Å; Q485-S489 PolarHBondContact O-N 3.13Å; Q485-S489 PolarHBondContact O-OG 3.3Å; Q485-S489 VanDerWaalsContact O-OG 3.13Å; Q485-H531 PolarHBondContact NE2-CE1 2.88Å; Q485-H531 PolarHBondContact NE2-ND1 2.64Å; Q485-H531 VanDerWaalsContact NE2-ND1 3.18Å; Q485-S532 PolarHBondContact NE2-OG 3.12Å; Q485-S532 PolarHBondContact OE1-OG 3.46Å; Q485-S532 VanDerWaalsContact OE1-OG 3.07Å; Q485-L533 HydrophobicContact CG-CB 4.48Å; Q485-L533 HydrophobicContact CG-CD1 3.66Å; Q485-L533 VanDerWaalsContact NE2-CB 3.33Å
486D97.9Very high95.9Very high109 Ų10948 Ų4858%0.58325%0.25SS*.Hα-helixtrans-62.3-46.3178.9-74.4-18.6000110.5D482 M483 S489 E490D482-D486 PolarHBondContact O-N 2.78Å; D482-D486 VanDerWaalsContact O-N 3.11Å; M483-D486 PolarHBondContact O-N 3.5Å; D486-S489 PolarHBondContact O-N 2.93Å; D486-E490 WeakPolarHBondContact O-CB 3.39Å; D486-E490 PolarHBondContact O-N 2.93Å
487W98.3Very high94.6Very high38 Ų3850.1 Ų50.114%0.14427%0.265CS..Hα-helixtrans-70-32.7-179.6-62.6-23.4000113.4H426 Y428 F444 M483 L484 S489 E490 F491H426-W487 HydrophobicContact CB-CD2 3.7Å; H426-W487 HydrophobicContact CB-CE3 3.42Å; H426-W487 VanDerWaalsContact CB-CE3 3.42Å; H426-W487 HydrophobicContact CB-CG 4.45Å; H426-W487 HydrophobicContact CB-CH2 3.82Å; H426-W487 HydrophobicContact CB-CZ2 4.09Å; H426-W487 HydrophobicContact CB-CZ3 3.47Å; H426-W487 VanDerWaalsContact CB-CZ3 3.47Å; H426-W487 AromaticContact CG-CD2 3.91Å; Y428-W487 AromaticContact CD1-CH2 3.67Å; Y428-W487 HydrophobicContact CD1-CH2 3.67Å; Y428-W487 AromaticContact CD1-CZ3 3.52Å; Y428-W487 HydrophobicContact CD1-CZ3 3.52Å; Y428-W487 HydrophobicContact CE1-CE3 4.18Å; Y428-W487 AromaticContact CE1-CH2 3.98Å; Y428-W487 HydrophobicContact CE1-CH2 3.98Å; Y428-W487 AromaticContact CE1-CZ3 3.36Å; Y428-W487 HydrophobicContact CE1-CZ3 3.36Å; Y428-W487 HydrophobicContact CG-CZ3 4.49Å; F444-W487 HydrophobicContact CE1-CB 4.17Å; F444-W487 HydrophobicContact CE2-CB 3.83Å; F444-W487 HydrophobicContact CE2-CE3 4.33Å; F444-W487 HydrophobicContact CZ-CB 3.43Å; F444-W487 VanDerWaalsContact CZ-CB 3.43Å; F444-W487 HydrophobicContact CZ-CE3 4.25Å; F444-W487 HydrophobicContact CZ-CG 4.44Å; M483-W487 HydrophobicContact CB-CD2 4.33Å; M483-W487 HydrophobicContact CB-CE3 4.3Å; M483-W487 HydrophobicContact CB-CH2 3.95Å; M483-W487 HydrophobicContact CB-CZ2 3.94Å; M483-W487 HydrophobicContact CB-CZ3 4.14Å; M483-W487 HydrophobicContact CG-CH2 4.43Å; M483-W487 HydrophobicContact CG-CZ2 4.19Å; M483-W487 WeakPolarHBondContact O-CB 3.45Å; M483-W487 VanDerWaalsContact O-CD2 3.25Å; M483-W487 PolarHBondContact O-N 3.35Å; M483-W487 HydrophobicContact SD-CH2 3.99Å; M483-W487 HydrophobicContact SD-CZ2 3.96Å; L484-W487 PolarHBondContact O-N 3.19Å; W487-S489 VanDerWaalsContact C-N 3.34Å; W487-E490 PolarHBondContact O-N 2.92Å; W487-F491 VanDerWaalsContact O-CB 3.24Å; W487-F491 WeakPolarHBondContact O-CB 3.43Å; W487-F491 PolarHBondContact O-N 3.06Å
488L97.2Very high92.5Very high14 Ų1456 Ų567%0.07331%0.306CS..Hα-helixtrans-57.4-50.2170.4-77.1162.3000110.7F444 S463 L484 Q485 F491 R492 I512 L533 Y537F444-L488 HydrophobicContact CD1-CD2 3.97Å; F444-L488 HydrophobicContact CD1-CG 4.46Å; F444-L488 HydrophobicContact CE1-CD2 3.77Å; F444-L488 HydrophobicContact CE1-CG 3.84Å; S463-L488 WeakPolarHBondContact OG-CD2 2.95Å; L484-L488 HydrophobicContact CD1-CD1 4.35Å; L484-L488 HydrophobicContact CD1-CG 4.35Å; L484-L488 HydrophobicContact CG-CD1 4.1Å; L484-L488 WeakPolarHBondContact O-CB 3.29Å; L484-L488 WeakPolarHBondContact O-CD1 3.29Å; L484-L488 WeakPolarHBondContact O-CG 3.35Å; L484-L488 PolarHBondContact O-N 2.94Å; Q485-L488 PolarHBondContact O-N 2.9Å; L488-F491 PolarHBondContact O-N 3.32Å; L488-R492 VanDerWaalsContact O-CB 3.3Å; L488-R492 WeakPolarHBondContact O-CB 3.38Å; L488-R492 PolarHBondContact O-N 2.85Å; L488-I512 HydrophobicContact CD1-CD1 3.4Å; L488-I512 HydrophobicContact CD1-CG1 4.15Å; L488-I512 HydrophobicContact CD2-CD1 4.32Å; L488-I512 HydrophobicContact CD2-CG1 4.18Å; L488-L533 HydrophobicContact CD1-CD1 4.33Å; L488-Y537 HydrophobicContact CD1-CE2 3.93Å
489S94.8Very high90.4Very high83 Ų8357.7 Ų57.758%0.5832%0.318SS*.Hα-helixtrans-64.3-42.9-179.6-60.20000111.6Q485 D486 W487 K493Q485-S489 PolarHBondContact O-N 3.13Å; Q485-S489 PolarHBondContact O-OG 3.3Å; Q485-S489 VanDerWaalsContact O-OG 3.13Å; D486-S489 PolarHBondContact O-N 2.93Å; W487-S489 VanDerWaalsContact C-N 3.34Å; S489-K493 VanDerWaalsContact O-CB 3.29Å; S489-K493 WeakPolarHBondContact O-CB 3.44Å; S489-K493 PolarHBondContact O-N 2.88Å
490E96.2Very high88.2Confident115 Ų11560.6 Ų60.654%0.53734%0.343SS..Hα-helixtrans-64.5-47.6176.9-174.3177.9-170.900112D486 W487 R492 K493 S494D486-E490 WeakPolarHBondContact O-CB 3.39Å; D486-E490 PolarHBondContact O-N 2.93Å; W487-E490 PolarHBondContact O-N 2.92Å; E490-R492 PolarHBondContact O-N 3.36Å; E490-K493 PolarHBondContact O-N 3.4Å; E490-S494 WeakPolarHBondContact O-CB 3.31Å; E490-S494 PolarHBondContact O-N 3.04Å; E490-S494 PolarHBondContact O-OG 2.67Å
491F96Very high86.2Confident8 Ų864.6 Ų64.64%0.03538%0.375CS..Hα-helixtrans-60.2-48179.2-178.6-106.1000110.7M1 D422 A424 F444 K446 Y461 W487 L488 K493 S494 T495M1-F491 HydrophobicContact CE-CD2 4.43Å; M1-F491 HydrophobicContact CE-CE2 4.37Å; M1-F491 HydrophobicContact SD-CE2 4.31Å; D422-F491 HydrophobicContact CB-CE2 4.36Å; D422-F491 HydrophobicContact CB-CZ 4.02Å; A424-F491 HydrophobicContact CB-CD2 3.62Å; A424-F491 HydrophobicContact CB-CE2 3.65Å; F444-F491 HydrophobicContact CB-CB 4.16Å; F444-F491 HydrophobicContact CB-CD1 3.63Å; F444-F491 HydrophobicContact CB-CD2 3.78Å; F444-F491 HydrophobicContact CB-CE1 3.86Å; F444-F491 HydrophobicContact CB-CE2 4.02Å; F444-F491 HydrophobicContact CB-CG 3.57Å; F444-F491 HydrophobicContact CB-CZ 4.05Å; F444-F491 HydrophobicContact CD1-CB 4.39Å; F444-F491 HydrophobicContact CG-CB 4.24Å; F444-F491 HydrophobicContact CG-CD1 4.47Å; F444-F491 HydrophobicContact CG-CG 4.18Å; K446-F491 HydrophobicContact CB-CE1 4.23Å; K446-F491 HydrophobicContact CB-CZ 4.31Å; Y461-F491 HydrophobicContact CD1-CD1 4.04Å; Y461-F491 AromaticContact CD1-CE1 3.87Å; Y461-F491 HydrophobicContact CD1-CE1 3.87Å; Y461-F491 HydrophobicContact CE1-CD1 4.16Å; Y461-F491 HydrophobicContact CE1-CE1 4Å; W487-F491 VanDerWaalsContact O-CB 3.24Å; W487-F491 WeakPolarHBondContact O-CB 3.43Å; W487-F491 PolarHBondContact O-N 3.06Å; L488-F491 PolarHBondContact O-N 3.32Å; F491-K493 PolarHBondContact O-N 3.38Å; F491-S494 PolarHBondContact O-N 3.21Å; F491-S494 PolarHBondContact O-OG 2.75Å; F491-T495 HydrophobicContact CD2-CG2 4.1Å; F491-T495 HydrophobicContact CE1-CG2 4.39Å; F491-T495 HydrophobicContact CE2-CG2 3.74Å; F491-T495 HydrophobicContact CZ-CG2 3.91Å; F491-T495 WeakPolarHBondContact O-CB 3.3Å; F491-T495 WeakPolarHBondContact O-CG2 3.31Å; F491-T495 PolarHBondContact O-N 2.83Å; F491-T495 PolarHBondContact O-OG1 3.18Å
492R93.4Very high84.3Confident65 Ų6568.4 Ų68.425%0.24540%0.396CS..Hα-helixtrans-59.3-45.9176.9-175.1168.3175.7176.1-2.1111.9Y461 L488 E490 S494 T495 S496 D510 G622Y461-R492 HydrophobicContact CE2-CG 4.33Å; L488-R492 VanDerWaalsContact O-CB 3.3Å; L488-R492 WeakPolarHBondContact O-CB 3.38Å; L488-R492 PolarHBondContact O-N 2.85Å; E490-R492 PolarHBondContact O-N 3.36Å; R492-S494 PolarHBondContact O-N 3.01Å; R492-T495 PolarHBondContact O-N 3.41Å; R492-S496 WeakPolarHBondContact O-CB 3.39Å; R492-S496 PolarHBondContact O-N 3.07Å; R492-S496 PolarHBondContact O-OG 3.23Å; R492-D510 IonicContact NH1-OD2 3.66Å; R492-G622 VanDerWaalsContact NH2-C 3.33Å; R492-G622 PolarHBondContact NH2-O 2.99Å
493K92.5Very high82.7Confident176 Ų17667.3 Ų67.377%0.76539%0.393SS*.Hα-helixtrans-62-42.3176.2-178.1-178.3176.9-176.60112.5S489 E490 F491 T495S489-K493 VanDerWaalsContact O-CB 3.29Å; S489-K493 WeakPolarHBondContact O-CB 3.44Å; S489-K493 PolarHBondContact O-N 2.88Å; E490-K493 PolarHBondContact O-N 3.4Å; F491-K493 PolarHBondContact O-N 3.38Å; K493-T495 VanDerWaalsContact C-N 3.33Å; K493-T495 PolarHBondContact O-N 3.47Å
494S92.7Very high81.8Confident71 Ų7171.6 Ų71.650%0.49741%0.413SS..Hα-helixtrans-72.8-24.5-176.473.30000113.8E490 F491 R492E490-S494 WeakPolarHBondContact O-CB 3.31Å; E490-S494 PolarHBondContact O-N 3.04Å; E490-S494 PolarHBondContact O-OG 2.67Å; F491-S494 PolarHBondContact O-N 3.21Å; F491-S494 PolarHBondContact O-OG 2.75Å; R492-S494 PolarHBondContact O-N 3.01Å
495T92.3Very high81.4Confident9 Ų973.2 Ų73.26%0.05542%0.42CS..Hα-helixtrans-108.1-6.6-176.4580000113.4M1 D422 K446 Y461 F491 R492 K493 S497M1-T495 HydrophobicContact CE-CG2 4.05Å; M1-T495 HydrophobicContact SD-CG2 4.45Å; D422-T495 HydrophobicContact CB-CG2 3.68Å; K446-T495 PolarHBondContact NZ-O 3.12Å; Y461-T495 WeakPolarHBondContact CE1-OG1 3.25Å; Y461-T495 PolarHBondContact OH-OG1 3Å; F491-T495 HydrophobicContact CD2-CG2 4.1Å; F491-T495 HydrophobicContact CE1-CG2 4.39Å; F491-T495 HydrophobicContact CE2-CG2 3.74Å; F491-T495 HydrophobicContact CZ-CG2 3.91Å; F491-T495 WeakPolarHBondContact O-CB 3.3Å; F491-T495 WeakPolarHBondContact O-CG2 3.31Å; F491-T495 PolarHBondContact O-N 2.83Å; F491-T495 PolarHBondContact O-OG1 3.18Å; R492-T495 PolarHBondContact O-N 3.41Å; K493-T495 VanDerWaalsContact C-N 3.33Å; K493-T495 PolarHBondContact O-N 3.47Å; T495-S497 PolarHBondContact O-N 3.19Å
496S85.8Confident81Confident54 Ų5471.8 Ų71.838%0.37841%0.414SS..SBendtrans-70.6121.7172.1-65.90000110.4R492 S498R492-S496 WeakPolarHBondContact O-CB 3.39Å; R492-S496 PolarHBondContact O-N 3.07Å; R492-S496 PolarHBondContact O-OG 3.23Å; S496-S498 PolarHBondContact O-N 3.12Å
497S68Low80.9Confident47 Ų4767.4 Ų67.433%0.32939%0.391SS..  trans-68.6111.1177.2-72.30000110.8T495 N502 E505T495-S497 PolarHBondContact O-N 3.19Å; S497-N502 PolarHBondContact OG-ND2 2.76Å; S497-E505 PolarHBondContact N-OE2 3.46Å; S497-E505 VanDerWaalsContact OG-CD 3.28Å; S497-E505 PolarHBondContact OG-OE1 3.41Å
498S54Low80.7Confident124 Ų12465.7 Ų65.787%0.86738%0.384SS*.  trans-104.44.2167.857.10000113.1S496S496-S498 PolarHBondContact O-N 3.12Å
499S53.3Low80.7Confident59 Ų5965 Ų6541%0.41338%0.381SS..  trans-79.6129.5-178.7166.70000110.9A501 N502S499-A501 PolarHBondContact O-N 2.83Å; S499-A501 WeakPolarHBondContact OG-CB 3.35Å; S499-A501 PolarHBondContact OG-N 2.78Å; S499-A501 VanDerWaalsContact OG-N 3.13Å; S499-N502 PolarHBondContact O-N 2.97Å; S499-N502 VanDerWaalsContact O-N 3.17Å
500T50.3Low80.8Confident155 Ų15561.3 Ų61.395%0.95135%0.354SS*.THydrogen-bonded Turntrans-61.8-7.4171.854.20000114
501A55.3Low80.9Confident83 Ų8355.8 Ų55.869%0.68633%0.329SS*.THydrogen-bonded Turntrans-96.2-7.617900000114S499S499-A501 PolarHBondContact O-N 2.83Å; S499-A501 WeakPolarHBondContact OG-CB 3.35Å; S499-A501 PolarHBondContact OG-N 2.78Å; S499-A501 VanDerWaalsContact OG-N 3.13Å
502N59.8Low81.1Confident80 Ų8055.5 Ų55.543%0.42833%0.327SS..SBendtrans-106.6147.1177.7-72.8-13.1000110.5S497 S499S497-N502 PolarHBondContact OG-ND2 2.76Å; S499-N502 PolarHBondContact O-N 2.97Å; S499-N502 VanDerWaalsContact O-N 3.17Å
503P64.4Low81.3Confident54 Ų5452.5 Ų52.535%0.35132%0.317SS..  trans-59.9144.1169.626.4-32.7000109.6
504E80.3Confident81.6Confident126 Ų12644.1 Ų44.159%0.58928%0.28SS*.  trans-54.7139.8173-170.8174.8-166.500110Q456 R457 L506Q456-E504 WeakPolarHBondContact CB-O 3.4Å; Q456-E504 HydrophobicContact CG-CB 4.22Å; Q456-E504 PolarHBondContact NE2-OE2 3.38Å; R457-E504 PolarHBondContact N-O 2.96Å; E504-L506 HydrophobicContact CG-CD2 4.45Å
505E88.4Confident81.9Confident33 Ų3340.8 Ų40.815%0.15426%0.257CS..EExtended strand (participates in β ladder)trans-108.1124.1-174.6-66177.6157.700110.2K446 R457 V459 S497K446-E505 IonicContact NZ-OE1 2.93Å; K446-E505 PolarHBondContact NZ-OE1 3.31Å; K446-E505 IonicContact NZ-OE2 2.68Å; K446-E505 PolarHBondContact NZ-OE2 2.81Å; R457-E505 HydrophobicContact CB-CG 4.49Å; R457-E505 IonicContact NH1-OE1 3.74Å; R457-E505 CarbonylContact O-C 3.55Å; R457-E505 WeakPolarHBondContact O-CA 3.29Å; V459-E505 HydrophobicContact CG1-CG 4.49Å; V459-E505 HydrophobicContact CG2-CB 4.31Å; S497-E505 PolarHBondContact N-OE2 3.46Å; S497-E505 VanDerWaalsContact OG-CD 3.28Å; S497-E505 PolarHBondContact OG-OE1 3.41Å
506L91.2Very high82.2Confident5 Ų540.5 Ų40.53%0.02626%0.255CS..EExtended strand (participates in β ladder)trans-101.5121.9177.4-50.5-166.7000109.5T452 Q456 R457 I458 V459 E504 Y624 W627T452-L506 HydrophobicContact CG2-CD1 3.41Å; T452-L506 VanDerWaalsContact CG2-CD1 3.41Å; T452-L506 HydrophobicContact CG2-CG 4.37Å; Q456-L506 HydrophobicContact CB-CG 4.34Å; R457-L506 PolarHBondContact O-N 2.73Å; I458-L506 CarbonylContact C-O 3.54Å; I458-L506 WeakPolarHBondContact CA-O 3.48Å; V459-L506 PolarHBondContact N-O 2.91Å; E504-L506 HydrophobicContact CG-CD2 4.45Å; L506-Y624 HydrophobicContact CB-CD2 4.41Å; L506-Y624 HydrophobicContact CB-CG 4.34Å; L506-Y624 HydrophobicContact CD1-CD1 4.38Å; L506-Y624 HydrophobicContact CD1-CD2 4.32Å; L506-Y624 HydrophobicContact CD1-CE1 4.38Å; L506-Y624 HydrophobicContact CD1-CE2 4.3Å; L506-Y624 HydrophobicContact CD1-CG 4.34Å; L506-Y624 HydrophobicContact CD2-CD2 3.52Å; L506-Y624 HydrophobicContact CD2-CE2 3.59Å; L506-Y624 HydrophobicContact CD2-CG 4.23Å; L506-Y624 HydrophobicContact CG-CD2 4.29Å; L506-W627 HydrophobicContact CB-CH2 3.96Å; L506-W627 HydrophobicContact CB-CZ3 4.27Å; L506-W627 HydrophobicContact CD1-CH2 4.1Å; L506-W627 HydrophobicContact CD1-CZ2 3.91Å
507V93.8Very high82.7Confident17 Ų1739 Ų3910%0.10324%0.242CC..EExtended strand (participates in β ladder)trans-87.2114.4-178.5-173.90000109.8V459 Y461 L623 Y624V459-V507 HydrophobicContact CG2-CG2 4.03Å; V459-V507 CarbonylContact O-C 3.55Å; V459-V507 WeakPolarHBondContact O-CA 3.36Å; Y461-V507 HydrophobicContact CD2-CG1 3.85Å; Y461-V507 HydrophobicContact CE2-CG1 4.12Å; Y461-V507 HydrophobicContact CE2-CG2 3.97Å; V507-L623 HydrophobicContact CG1-CD2 3.91Å; V507-Y624 PolarHBondContact O-N 2.89Å; V507-Y624 VanDerWaalsContact O-N 3.12Å
508A94.7Very high84.1Confident1 Ų136.7 Ų36.71%0.00823%0.227CC..EExtended strand (participates in β ladder)trans-82.2-38.8-179.400000113.3W115 F124 V449 I458 V459 W627 V629 V655W115-A508 HydrophobicContact CZ3-CB 4.04Å; F124-A508 HydrophobicContact CE2-CB 4.45Å; V449-A508 HydrophobicContact CG2-CB 4.21Å; I458-A508 HydrophobicContact CG2-CB 3.84Å; V459-A508 PolarHBondContact O-N 3Å; A508-W627 HydrophobicContact CB-CE3 4.31Å; A508-W627 HydrophobicContact CB-CZ3 3.88Å; A508-V629 VanDerWaalsContact O-CG2 3.29Å; A508-V629 WeakPolarHBondContact O-CG2 3.33Å; A508-V655 HydrophobicContact CB-CG1 4.41Å; A508-V655 HydrophobicContact CB-CG2 4.42Å; A508-V655 WeakPolarHBondContact O-CG2 3.49Å
509F97.2Very high86.1Confident0 Ų030.8 Ų30.80%019%0.185CC..EExtended strand (participates in β ladder)trans-158.4159.5-178.254.6-102.3000110.9F124 F126 F364 V447 V449 G460 Y461 I462 V511 L653F124-F509 HydrophobicContact CB-CD1 4.37Å; F124-F509 HydrophobicContact CB-CE1 4.14Å; F124-F509 AromaticContact CD1-CE1 3.79Å; F124-F509 HydrophobicContact CD1-CE1 3.79Å; F124-F509 AromaticContact CD2-CD1 3.67Å; F124-F509 HydrophobicContact CD2-CD1 3.67Å; F124-F509 AromaticContact CD2-CE1 3.66Å; F124-F509 HydrophobicContact CD2-CE1 3.66Å; F124-F509 HydrophobicContact CE1-CE1 4.07Å; F124-F509 HydrophobicContact CE2-CD1 4.06Å; F124-F509 AromaticContact CE2-CE1 3.94Å; F124-F509 HydrophobicContact CE2-CE1 3.94Å; F124-F509 AromaticContact CG-CD1 3.96Å; F124-F509 HydrophobicContact CG-CD1 3.96Å; F124-F509 AromaticContact CG-CE1 3.57Å; F124-F509 HydrophobicContact CG-CE1 3.57Å; F124-F509 HydrophobicContact CZ-CE1 4.12Å; F126-F509 AromaticContact CE1-CD2 3.86Å; F126-F509 HydrophobicContact CE1-CD2 3.86Å; F126-F509 AromaticContact CE1-CE2 3.64Å; F126-F509 HydrophobicContact CE1-CE2 3.64Å; F126-F509 HydrophobicContact CE1-CZ 4.13Å; F126-F509 HydrophobicContact CZ-CD1 4.05Å; F126-F509 AromaticContact CZ-CD2 3.59Å; F126-F509 HydrophobicContact CZ-CD2 3.59Å; F126-F509 HydrophobicContact CZ-CE1 4.11Å; F126-F509 AromaticContact CZ-CE2 3.66Å; F126-F509 HydrophobicContact CZ-CE2 3.66Å; F126-F509 AromaticContact CZ-CG 3.8Å; F126-F509 HydrophobicContact CZ-CG 3.8Å; F126-F509 AromaticContact CZ-CZ 3.92Å; F126-F509 HydrophobicContact CZ-CZ 3.92Å; F364-F509 HydrophobicContact CD2-CZ 4.47Å; F364-F509 HydrophobicContact CE2-CE1 4.16Å; F364-F509 HydrophobicContact CE2-CE2 4.22Å; F364-F509 AromaticContact CE2-CZ 3.53Å; F364-F509 HydrophobicContact CE2-CZ 3.53Å; F364-F509 HydrophobicContact CZ-CE1 4.42Å; F364-F509 HydrophobicContact CZ-CE2 4.43Å; F364-F509 AromaticContact CZ-CZ 3.62Å; F364-F509 HydrophobicContact CZ-CZ 3.62Å; V447-F509 HydrophobicContact CG2-CE2 4.24Å; V447-F509 HydrophobicContact CG2-CZ 4.01Å; V449-F509 HydrophobicContact CG1-CE1 3.9Å; V449-F509 HydrophobicContact CG1-CZ 3.81Å; V449-F509 HydrophobicContact CG2-CE1 4.4Å; G460-F509 WeakPolarHBondContact CA-O 3.5Å; Y461-F509 PolarHBondContact N-O 3.03Å; I462-F509 HydrophobicContact CD1-CE2 4.09Å; I462-F509 HydrophobicContact CG1-CE2 3.87Å; F509-V511 HydrophobicContact CD2-CG2 4.32Å; F509-L653 HydrophobicContact CB-CD1 4.24Å
510D97.9Very high88.2Confident5 Ų528 Ų283%0.02717%0.166CC..EExtended strand (participates in β ladder)trans-143.3113.2172.9-177.1-14.7000108.1Y461 R492 Y537 Y618 T619Y461-D510 WeakPolarHBondContact O-CA 3.43Å; R492-D510 IonicContact NH1-OD2 3.66Å; D510-Y537 VanDerWaalsContact CG-OH 3.25Å; D510-Y537 WeakPolarHBondContact OD1-CE1 3.29Å; D510-Y537 PolarHBondContact OD1-OH 2.78Å; D510-Y537 PolarHBondContact OD2-OH 3.05Å; D510-Y537 VanDerWaalsContact OD2-OH 3.14Å; D510-Y618 WeakPolarHBondContact O-CA 3.33Å; D510-T619 HydrophobicContact CB-CG2 3.63Å; D510-T619 PolarHBondContact O-N 2.92Å; D510-T619 VanDerWaalsContact O-N 3.11Å
511V98.7Very high90.2Very high0 Ų023 Ų230%014%0.136CC..EExtended strand (participates in β ladder)trans-125.8137.3-166.9172.40000110.8F126 Y461 I462 S463 F509 M616 L617 M651 L653F126-V511 HydrophobicContact CD1-CB 4.29Å; F126-V511 HydrophobicContact CD1-CG1 4.04Å; F126-V511 HydrophobicContact CD1-CG2 4.17Å; F126-V511 HydrophobicContact CD2-CG2 4.46Å; F126-V511 HydrophobicContact CE1-CB 4.2Å; F126-V511 HydrophobicContact CE1-CG1 4.45Å; F126-V511 HydrophobicContact CE1-CG2 3.83Å; F126-V511 HydrophobicContact CE2-CG2 4.16Å; F126-V511 HydrophobicContact CG-CG1 4.32Å; F126-V511 HydrophobicContact CG-CG2 4.48Å; F126-V511 HydrophobicContact CZ-CG2 3.84Å; Y461-V511 PolarHBondContact O-N 2.81Å; I462-V511 CarbonylContact C-O 3.51Å; I462-V511 WeakPolarHBondContact CA-O 3.4Å; S463-V511 PolarHBondContact N-O 2.78Å; F509-V511 HydrophobicContact CD2-CG2 4.32Å; V511-M616 HydrophobicContact CG1-SD 3.83Å; V511-L617 VanDerWaalsContact CA-O 3.3Å; V511-L617 WeakPolarHBondContact CA-O 3.05Å; V511-L617 WeakPolarHBondContact CG1-O 3.43Å; V511-M651 HydrophobicContact CG1-CE 4.26Å; V511-M651 HydrophobicContact CG2-CE 4.21Å; V511-L653 HydrophobicContact CG2-CD1 3.74Å
512I98.8Very high91.9Very high1 Ų119.4 Ų19.41%0.00511%0.106CC..EExtended strand (participates in β ladder)trans-119.4134.8171.3-55.7168.2000108.8S463 L484 L488 L533 Y537 L617S463-I512 CarbonylContact O-C 3.38Å; S463-I512 WeakPolarHBondContact O-CA 3.33Å; L484-I512 HydrophobicContact CD2-CG2 4.31Å; L488-I512 HydrophobicContact CD1-CD1 3.4Å; L488-I512 HydrophobicContact CD1-CG1 4.15Å; L488-I512 HydrophobicContact CD2-CD1 4.32Å; L488-I512 HydrophobicContact CD2-CG1 4.18Å; I512-L533 HydrophobicContact CD1-CD1 3.86Å; I512-Y537 HydrophobicContact CD1-CD1 3.47Å; I512-Y537 VanDerWaalsContact CD1-CD1 3.47Å; I512-Y537 HydrophobicContact CD1-CD2 3.52Å; I512-Y537 HydrophobicContact CD1-CE1 3.51Å; I512-Y537 HydrophobicContact CD1-CE2 3.57Å; I512-Y537 HydrophobicContact CD1-CG 3.47Å; I512-Y537 VanDerWaalsContact CD1-CG 3.47Å; I512-Y537 HydrophobicContact CG1-CD1 3.76Å; I512-Y537 HydrophobicContact CG1-CE1 3.59Å; I512-Y537 HydrophobicContact CG1-CE2 4.48Å; I512-Y537 HydrophobicContact CG1-CG 4.27Å; I512-L617 HydrophobicContact CB-CB 4.3Å; I512-L617 HydrophobicContact CB-CD1 4.43Å; I512-L617 PolarHBondContact N-O 2.95Å; I512-L617 PolarHBondContact O-N 3.33Å
513C98.8Very high93.4Very high3 Ų320.5 Ų20.52%0.0212%0.121CC..EExtended strand (participates in β ladder)trans-147.4169.7173.164.20000113.3C366 S463 C464 T465 Y615 M616C366-C513 WeakPolarHBondContact CB-SG 3.29Å; C366-C513 PolarHBondContact SG-SG 3.42Å; S463-C513 PolarHBondContact O-N 2.85Å; C464-C513 VanDerWaalsContact CA-O 3.31Å; C464-C513 WeakPolarHBondContact CA-O 3.34Å; T465-C513 PolarHBondContact N-O 3.28Å; C513-Y615 WeakPolarHBondContact CA-O 3.18Å; C513-Y615 VanDerWaalsContact CB-O 3.23Å; C513-Y615 WeakPolarHBondContact CB-O 3.41Å; C513-M616 HydrophobicContact CB-CE 3.74Å; C513-M616 HydrophobicContact CB-SD 3.53Å; C513-M616 VanDerWaalsContact CB-SD 3.53Å
514G98.5Very high94.6Very high0 Ų020.9 Ų20.90%012%0.117CC..EExtended strand (participates in β ladder)trans135.4-170.5171.900000113.4T465 L516 D614 Y615T465-G514 WeakPolarHBondContact O-CA 3.3Å; G514-L516 PolarHBondContact O-N 3.14Å; G514-D614 WeakPolarHBondContact O-CA 3.32Å; G514-Y615 PolarHBondContact N-O 2.88Å; G514-Y615 VanDerWaalsContact N-O 3.08Å; G514-Y615 PolarHBondContact O-N 2.84Å
515D98.6Very high95.2Very high1 Ų115 Ų151%0.0059%0.09CC..EExtended strand (participates in β ladder)trans-88.1105.7179.9-176.1-8.9000109.7N130 Q368 T465 H466 L467 N517 H646N130-D515 PolarHBondContact ND2-OD2 3.11Å; Q368-D515 HydrophobicContact CG-CB 4.31Å; T465-D515 PolarHBondContact O-N 3.15Å; H466-D515 WeakPolarHBondContact CA-O 3.42Å; H466-D515 IonicContact NE2-OD2 3.17Å; L467-D515 PolarHBondContact N-O 3.3Å; D515-N517 PolarHBondContact OD1-N 2.87Å; D515-N517 PolarHBondContact OD1-ND2 2.99Å; D515-H646 IonicContact OD2-CE1 2.83Å; D515-H646 PolarHBondContact OD2-CE1 3.04Å; D515-H646 VanDerWaalsContact OD2-CE1 3.28Å; D515-H646 IonicContact OD2-NE2 3.65Å
516L98.2Very high95.5Very high2 Ų218.8 Ų18.81%0.0111%0.106CC..  trans-88.9-7.7-179.5-55.1-167.5000112.8T465 L467 R477 G514 F518 I613 Y615T465-L516 HydrophobicContact CG2-CD2 3.49Å; T465-L516 VanDerWaalsContact CG2-CD2 3.49Å; L467-L516 HydrophobicContact CD1-CB 4.01Å; L467-L516 HydrophobicContact CD1-CD2 3.92Å; L467-L516 HydrophobicContact CD1-CG 4.49Å; L467-L516 HydrophobicContact CG-CB 4.44Å; L467-L516 HydrophobicContact CG-CD2 3.97Å; R477-L516 WeakPolarHBondContact CD-O 3.25Å; G514-L516 PolarHBondContact O-N 3.14Å; L516-F518 HydrophobicContact CB-CD1 3.74Å; L516-F518 HydrophobicContact CB-CE1 3.5Å; L516-F518 HydrophobicContact CB-CZ 4.21Å; L516-F518 HydrophobicContact CD1-CE1 3.8Å; L516-F518 HydrophobicContact CD1-CZ 3.84Å; L516-F518 HydrophobicContact CG-CE1 4.27Å; L516-F518 WeakPolarHBondContact O-CD1 3.38Å; L516-F518 PolarHBondContact O-N 3.48Å; L516-I613 PolarHBondContact N-O 3.26Å; L516-Y615 HydrophobicContact CB-CD2 3.72Å; L516-Y615 HydrophobicContact CB-CE2 3.89Å; L516-Y615 HydrophobicContact CD1-CD1 4.33Å; L516-Y615 HydrophobicContact CD1-CD2 3.44Å; L516-Y615 VanDerWaalsContact CD1-CD2 3.44Å; L516-Y615 HydrophobicContact CD1-CE2 3.98Å; L516-Y615 HydrophobicContact CD1-CG 3.63Å; L516-Y615 HydrophobicContact CG-CD2 3.49Å; L516-Y615 VanDerWaalsContact CG-CD2 3.49Å; L516-Y615 HydrophobicContact CG-CE2 4.14Å; L516-Y615 HydrophobicContact CG-CG 4.06Å
517N97.3Very high95.8Very high22 Ų2223.3 Ų23.312%0.11813%0.13CC..SBendtrans55.618.4178.1-82.8-73.4000115.9H466 L467 Q468 A469 R477 D515H466-N517 PolarHBondContact CD2-ND2 3.25Å; H466-N517 VanDerWaalsContact CD2-ND2 3.34Å; H466-N517 PolarHBondContact NE2-ND2 3.09Å; H466-N517 VanDerWaalsContact NE2-ND2 3.2Å; L467-N517 PolarHBondContact O-ND2 3.12Å; L467-N517 VanDerWaalsContact O-ND2 3.16Å; Q468-N517 VanDerWaalsContact O-CB 3.26Å; Q468-N517 WeakPolarHBondContact O-CB 3.32Å; A469-N517 VanDerWaalsContact CA-CG 3.49Å; R477-N517 PolarHBondContact NH1-O 3.39Å; D515-N517 PolarHBondContact OD1-N 2.87Å; D515-N517 PolarHBondContact OD1-ND2 2.99Å
518F97.1Very high96Very high0 Ų022.5 Ų22.50%013%0.125CC..  trans-136.1142.8172.273.4-100000109.9L467 L481 L516 D525 E528 F534 Y615L467-F518 HydrophobicContact CD1-CE1 4.26Å; L481-F518 HydrophobicContact CD1-CE1 3.82Å; L481-F518 HydrophobicContact CD1-CZ 4.18Å; L481-F518 HydrophobicContact CD2-CE1 4.28Å; L516-F518 HydrophobicContact CB-CD1 3.74Å; L516-F518 HydrophobicContact CB-CE1 3.5Å; L516-F518 HydrophobicContact CB-CZ 4.21Å; L516-F518 HydrophobicContact CD1-CE1 3.8Å; L516-F518 HydrophobicContact CD1-CZ 3.84Å; L516-F518 HydrophobicContact CG-CE1 4.27Å; L516-F518 WeakPolarHBondContact O-CD1 3.38Å; L516-F518 PolarHBondContact O-N 3.48Å; F518-D525 WeakPolarHBondContact CA-OD2 3.19Å; F518-D525 HydrophobicContact CB-CB 3.88Å; F518-E528 HydrophobicContact CB-CB 4.09Å; F518-E528 HydrophobicContact CB-CG 4.1Å; F518-E528 HydrophobicContact CD1-CB 3.61Å; F518-E528 HydrophobicContact CD1-CG 3.87Å; F518-E528 HydrophobicContact CD2-CB 3.45Å; F518-E528 VanDerWaalsContact CD2-CB 3.45Å; F518-E528 HydrophobicContact CD2-CG 4.36Å; F518-E528 HydrophobicContact CE1-CB 3.81Å; F518-E528 HydrophobicContact CE1-CG 4.38Å; F518-E528 HydrophobicContact CE2-CB 3.66Å; F518-E528 HydrophobicContact CG-CB 3.44Å; F518-E528 VanDerWaalsContact CG-CB 3.44Å; F518-E528 HydrophobicContact CG-CG 3.87Å; F518-E528 HydrophobicContact CZ-CB 3.84Å; F518-F534 AromaticContact CE2-CE2 3.99Å; F518-F534 HydrophobicContact CE2-CE2 3.99Å; F518-F534 AromaticContact CE2-CZ 3.93Å; F518-F534 HydrophobicContact CE2-CZ 3.93Å; F518-F534 AromaticContact CZ-CE2 3.78Å; F518-F534 HydrophobicContact CZ-CE2 3.78Å; F518-F534 AromaticContact CZ-CZ 3.7Å; F518-F534 HydrophobicContact CZ-CZ 3.7Å; F518-Y615 HydrophobicContact CE2-CE2 4.36Å; F518-Y615 AromaticContact CE2-CZ 3.94Å; F518-Y615 WeakPolarHBondContact CE2-OH 3.41Å; F518-Y615 VanDerWaalsContact O-CE2 3.27Å; F518-Y615 WeakPolarHBondContact O-CE2 3.47Å; F518-Y615 PolarHBondContact O-OH 2.73Å
519D95.8Very high96.1Very high0 Ų022.8 Ų22.80%013%0.126CC..  trans-94.6167.9-179.867.348.7000112.6C521 S522 D525 Q529 R611 R612 I613D519-C521 PolarHBondContact OD1-N 2.96Å; D519-S522 VanDerWaalsContact CG-OG 3.31Å; D519-S522 WeakPolarHBondContact OD1-CA 3.48Å; D519-S522 WeakPolarHBondContact OD1-CB 3.4Å; D519-S522 PolarHBondContact OD1-N 3.46Å; D519-S522 PolarHBondContact OD1-OG 3.39Å; D519-S522 VanDerWaalsContact OD2-CB 3.29Å; D519-S522 WeakPolarHBondContact OD2-CB 3.48Å; D519-S522 PolarHBondContact OD2-OG 2.82Å; D519-D525 VanDerWaalsContact CG-OD2 3.32Å; D519-D525 PolarHBondContact N-OD2 3.12Å; D519-D525 WeakPolarHBondContact O-CB 3.44Å; D519-Q529 VanDerWaalsContact O-CG 3.3Å; D519-Q529 WeakPolarHBondContact O-CG 3.16Å; D519-Q529 PolarHBondContact O-NE2 3.45Å; D519-R611 HydrophobicContact CB-CB 4.03Å; D519-R611 HydrophobicContact CB-CG 4.3Å; D519-R611 WeakPolarHBondContact OD2-CG 3.38Å; D519-R611 IonicContact OD2-CZ 3.85Å; D519-R611 IonicContact OD2-NE 3.36Å; D519-R611 PolarHBondContact OD2-NE 3.38Å; D519-R611 IonicContact OD2-NH2 3.27Å; D519-R611 PolarHBondContact OD2-NH2 3.02Å; D519-R612 WeakPolarHBondContact CA-O 3.34Å; D519-I613 HydrophobicContact CB-CG2 4.19Å
520N96.7Very high96.1Very high0 Ų028 Ų280%015%0.15CC..SBendtrans-106.132.8173.6-166.151.3000112.5R542 G544 G546 E547 D548N520-R542 PolarHBondContact OD1-NH1 2.87Å; N520-G544 PolarHBondContact ND2-O 3.34Å; N520-G544 VanDerWaalsContact ND2-O 3.11Å; N520-G544 PolarHBondContact OD1-O 2.98Å; N520-G546 CarbonylContact O-C 3.6Å; N520-G546 WeakPolarHBondContact O-CA 3.34Å; N520-G546 PolarHBondContact OD1-N 3.07Å; N520-E547 PolarHBondContact ND2-O 2.64Å; N520-E547 PolarHBondContact O-N 2.93Å; N520-D548 WeakPolarHBondContact CB-OD1 3.42Å; N520-D548 PolarHBondContact ND2-OD1 2.95Å
521C92.4Very high96.2Very high49 Ų4928.5 Ų28.533%0.33115%0.153SC..SBendtrans-140.9-21.7-178680000115.1D519D519-C521 PolarHBondContact OD1-N 2.96Å
522S91.8Very high96.1Very high8 Ų830.8 Ų30.86%0.05617%0.169CC..  trans-88.7152.3-179.1780000111.6D519 E524 D525 Q529D519-S522 VanDerWaalsContact CG-OG 3.31Å; D519-S522 WeakPolarHBondContact OD1-CA 3.48Å; D519-S522 WeakPolarHBondContact OD1-CB 3.4Å; D519-S522 PolarHBondContact OD1-N 3.46Å; D519-S522 PolarHBondContact OD1-OG 3.39Å; D519-S522 VanDerWaalsContact OD2-CB 3.29Å; D519-S522 WeakPolarHBondContact OD2-CB 3.48Å; D519-S522 PolarHBondContact OD2-OG 2.82Å; S522-E524 PolarHBondContact O-N 3.37Å; S522-D525 PolarHBondContact OG-N 2.98Å; S522-D525 PolarHBondContact OG-OD2 3.45Å; S522-Q529 PolarHBondContact O-NE2 2.92Å
523S90.3Very high96.1Very high104 Ų10430.8 Ų30.873%0.72717%0.168SC*.SBendtrans-74.5-15.3171.9570000113.6
524E89.8Confident96Very high61 Ų6131.7 Ų31.729%0.28517%0.172SC..THydrogen-bonded Turntrans-75.6-34.8-177.6-60-169.9153.900111.1T474 S522 K526 K593T474-E524 PolarHBondContact OG1-O 2.84Å; S522-E524 PolarHBondContact O-N 3.37Å; E524-K526 VanDerWaalsContact C-N 3.31Å; E524-K526 PolarHBondContact O-N 3.16Å; E524-K593 WeakPolarHBondContact OE1-CE 3.46Å; E524-K593 IonicContact OE1-NZ 2.83Å
525D93.9Very high95.9Very high3 Ų336.8 Ų36.82%0.01620%0.203CC..THydrogen-bonded Turntrans-93.418.8-177.5-67-30.5000112.9R477 F518 D519 S522 L527 E528 Q529 R611R477-D525 IonicContact CZ-OD1 2.6Å; R477-D525 IonicContact NH2-OD1 3.28Å; R477-D525 PolarHBondContact NH2-OD1 3.2Å; F518-D525 WeakPolarHBondContact CA-OD2 3.19Å; F518-D525 HydrophobicContact CB-CB 3.88Å; D519-D525 VanDerWaalsContact CG-OD2 3.32Å; D519-D525 PolarHBondContact N-OD2 3.12Å; D519-D525 WeakPolarHBondContact O-CB 3.44Å; S522-D525 PolarHBondContact OG-N 2.98Å; S522-D525 PolarHBondContact OG-OD2 3.45Å; D525-L527 VanDerWaalsContact C-N 3.32Å; D525-L527 PolarHBondContact O-N 2.98Å; D525-E528 VanDerWaalsContact CA-OE2 3.23Å; D525-E528 WeakPolarHBondContact CA-OE2 3.49Å; D525-E528 PolarHBondContact O-N 3.27Å; D525-E528 VanDerWaalsContact O-OE2 3.05Å; D525-Q529 WeakPolarHBondContact O-CB 3.5Å; D525-Q529 VanDerWaalsContact O-CD 3.29Å; D525-Q529 WeakPolarHBondContact O-CG 3.44Å; D525-Q529 PolarHBondContact O-N 2.91Å; D525-R611 IonicContact OD2-NH2 2.79Å; D525-R611 PolarHBondContact OD2-NH2 3.26Å
526K94.6Very high95.8Very high113 Ų11340.6 Ų40.649%0.49122%0.221SC..Hα-helixtrans-60.9-35.3-172-178.9179.6174.7-1750113.7E524 Q530E524-K526 VanDerWaalsContact C-N 3.31Å; E524-K526 PolarHBondContact O-N 3.16Å; K526-Q530 VanDerWaalsContact O-CG 3.31Å; K526-Q530 WeakPolarHBondContact O-CG 3.37Å; K526-Q530 PolarHBondContact O-N 2.77Å
527L96.7Very high95.8Very high100 Ų10041.5 Ų41.552%0.52422%0.224SC..Hα-helixtrans-73.3-40.2-176.4-59.5-177.9000110.7T474 D525 Q530 H531T474-L527 HydrophobicContact CG2-CB 3.55Å; T474-L527 HydrophobicContact CG2-CD1 3.7Å; T474-L527 HydrophobicContact CG2-CG 3.9Å; D525-L527 VanDerWaalsContact C-N 3.32Å; D525-L527 PolarHBondContact O-N 2.98Å; L527-Q530 PolarHBondContact O-N 2.72Å; L527-H531 PolarHBondContact O-N 3.49Å
528E97.9Very high95.8Very high0 Ų044.7 Ų44.70%024%0.237CC..Hα-helixtrans-64-43.3173.7-55.493.6140.900110.8T474 R477 L481 F518 D525 Q530 H531 F534T474-E528 WeakPolarHBondContact CA-OE1 3.49Å; T474-E528 WeakPolarHBondContact CB-OE1 3.41Å; T474-E528 VanDerWaalsContact CG2-CD 3.41Å; T474-E528 HydrophobicContact CG2-CG 4.4Å; T474-E528 WeakPolarHBondContact CG2-OE2 3.38Å; T474-E528 PolarHBondContact OG1-OE1 2.89Å; T474-E528 PolarHBondContact OG1-OE2 3.5Å; R477-E528 HydrophobicContact CB-CG 3.88Å; R477-E528 IonicContact CZ-OE1 2.82Å; R477-E528 IonicContact NE-OE1 2.86Å; R477-E528 PolarHBondContact NE-OE1 2.85Å; R477-E528 IonicContact NH2-OE1 2.8Å; R477-E528 PolarHBondContact NH2-OE1 3.09Å; L481-E528 HydrophobicContact CD1-CB 4.25Å; F518-E528 HydrophobicContact CB-CB 4.09Å; F518-E528 HydrophobicContact CB-CG 4.1Å; F518-E528 HydrophobicContact CD1-CB 3.61Å; F518-E528 HydrophobicContact CD1-CG 3.87Å; F518-E528 HydrophobicContact CD2-CB 3.45Å; F518-E528 VanDerWaalsContact CD2-CB 3.45Å; F518-E528 HydrophobicContact CD2-CG 4.36Å; F518-E528 HydrophobicContact CE1-CB 3.81Å; F518-E528 HydrophobicContact CE1-CG 4.38Å; F518-E528 HydrophobicContact CE2-CB 3.66Å; F518-E528 HydrophobicContact CG-CB 3.44Å; F518-E528 VanDerWaalsContact CG-CB 3.44Å; F518-E528 HydrophobicContact CG-CG 3.87Å; F518-E528 HydrophobicContact CZ-CB 3.84Å; D525-E528 VanDerWaalsContact CA-OE2 3.23Å; D525-E528 WeakPolarHBondContact CA-OE2 3.49Å; D525-E528 PolarHBondContact O-N 3.27Å; D525-E528 VanDerWaalsContact O-OE2 3.05Å; E528-Q530 PolarHBondContact O-N 3.31Å; E528-H531 WeakPolarHBondContact O-CB 3.19Å; E528-H531 PolarHBondContact O-N 2.94Å; E528-F534 WeakPolarHBondContact O-CE2 3.33Å
529Q97.6Very high95.9Very high6 Ų645.3 Ų45.33%0.02824%0.241CC..Hα-helixtrans-56.5-33.6175.2-70.6161.413.700112.3D519 S522 D525 R542 P545 G546D519-Q529 VanDerWaalsContact O-CG 3.3Å; D519-Q529 WeakPolarHBondContact O-CG 3.16Å; D519-Q529 PolarHBondContact O-NE2 3.45Å; S522-Q529 PolarHBondContact O-NE2 2.92Å; D525-Q529 WeakPolarHBondContact O-CB 3.5Å; D525-Q529 VanDerWaalsContact O-CD 3.29Å; D525-Q529 WeakPolarHBondContact O-CG 3.44Å; D525-Q529 PolarHBondContact O-N 2.91Å; Q529-R542 VanDerWaalsContact O-CZ 3.22Å; Q529-R542 PolarHBondContact O-NH1 3.05Å; Q529-R542 PolarHBondContact O-NH2 3.33Å; Q529-P545 HydrophobicContact CB-CB 4.08Å; Q529-G546 VanDerWaalsContact OE1-CA 3.24Å
530Q97.8Very high96Very high109 Ų10945.7 Ų45.751%0.50924%0.243SC..THydrogen-bonded Turntrans-924.2-178.6-68-178-24.200113.8K526 L527 E528 P545K526-Q530 VanDerWaalsContact O-CG 3.31Å; K526-Q530 WeakPolarHBondContact O-CG 3.37Å; K526-Q530 PolarHBondContact O-N 2.77Å; L527-Q530 PolarHBondContact O-N 2.72Å; E528-Q530 PolarHBondContact O-N 3.31Å; Q530-P545 HydrophobicContact CG-CB 3.78Å; Q530-P545 HydrophobicContact CG-CG 4.32Å
531H98.4Very high96Very high17 Ų1745.7 Ų45.78%0.07924%0.243CC..  trans-60.5144.6-178.6-161.3-89.1000112C478 L481 D482 Q485 L527 E528 L533 F534C478-H531 PolarHBondContact O-NE2 2.96Å; L481-H531 VanDerWaalsContact C-CE1 3.43Å; L481-H531 WeakPolarHBondContact CB-CE1 3.39Å; L481-H531 VanDerWaalsContact CB-NE2 3.33Å; L481-H531 WeakPolarHBondContact CB-NE2 3.22Å; L481-H531 HydrophobicContact CD1-CB 3.97Å; D482-H531 PolarHBondContact N-NE2 3.32Å; D482-H531 IonicContact OD1-CE1 2.88Å; D482-H531 IonicContact OD1-NE2 2.68Å; D482-H531 PolarHBondContact OD1-NE2 2.76Å; D482-H531 VanDerWaalsContact OD1-NE2 3.07Å; Q485-H531 PolarHBondContact NE2-CE1 2.88Å; Q485-H531 PolarHBondContact NE2-ND1 2.64Å; Q485-H531 VanDerWaalsContact NE2-ND1 3.18Å; L527-H531 PolarHBondContact O-N 3.49Å; E528-H531 WeakPolarHBondContact O-CB 3.19Å; E528-H531 PolarHBondContact O-N 2.94Å; H531-L533 WeakPolarHBondContact ND1-CB 3.4Å; H531-L533 PolarHBondContact ND1-N 2.86Å; H531-L533 VanDerWaalsContact ND1-N 3.19Å; H531-L533 PolarHBondContact O-N 3.08Å; H531-F534 HydrophobicContact CB-CD2 4.49Å; H531-F534 PolarHBondContact O-N 3.03Å
532S97.6Very high96.3Very high48 Ų4845.4 Ų45.434%0.33624%0.235SC..THydrogen-bonded Turntrans-60-12.5178.6520000113.5Q485 F534 T535 H536Q485-S532 PolarHBondContact NE2-OG 3.12Å; Q485-S532 PolarHBondContact OE1-OG 3.46Å; Q485-S532 VanDerWaalsContact OE1-OG 3.07Å; S532-F534 PolarHBondContact O-N 2.75Å; S532-T535 VanDerWaalsContact O-CB 3.25Å; S532-T535 WeakPolarHBondContact O-CB 3.31Å; S532-T535 PolarHBondContact O-N 3.47Å; S532-H536 PolarHBondContact O-CD2 2.8Å
533L97.9Very high96.5Very high0 Ų049.7 Ų49.70%026%0.256CS..Hα-helixtrans-62-40.1-177.2-176.570.5000109.2L481 L484 Q485 L488 I512 H531 T535 H536 Y537 L617L481-L533 HydrophobicContact CD2-CD2 3.76Å; L484-L533 HydrophobicContact CD2-CD2 4.17Å; Q485-L533 HydrophobicContact CG-CB 4.48Å; Q485-L533 HydrophobicContact CG-CD1 3.66Å; Q485-L533 VanDerWaalsContact NE2-CB 3.33Å; L488-L533 HydrophobicContact CD1-CD1 4.33Å; I512-L533 HydrophobicContact CD1-CD1 3.86Å; H531-L533 WeakPolarHBondContact ND1-CB 3.4Å; H531-L533 PolarHBondContact ND1-N 2.86Å; H531-L533 VanDerWaalsContact ND1-N 3.19Å; H531-L533 PolarHBondContact O-N 3.08Å; L533-T535 PolarHBondContact O-N 2.98Å; L533-H536 PolarHBondContact O-N 3.26Å; L533-H536 VanDerWaalsContact O-N 3.16Å; L533-Y537 HydrophobicContact CD1-CD2 3.91Å; L533-Y537 HydrophobicContact CD1-CE2 4.48Å; L533-Y537 PolarHBondContact O-N 2.91Å; L533-L617 HydrophobicContact CD2-CD1 4.13Å
534F97.9Very high96.8Very high23 Ų2345.4 Ų45.410%0.10123%0.228CC..Hα-helixtrans-73-4.9178.3-61.4-71.2000114F518 E528 H531 S532 Y537 D539 Y615 L617F518-F534 AromaticContact CE2-CE2 3.99Å; F518-F534 HydrophobicContact CE2-CE2 3.99Å; F518-F534 AromaticContact CE2-CZ 3.93Å; F518-F534 HydrophobicContact CE2-CZ 3.93Å; F518-F534 AromaticContact CZ-CE2 3.78Å; F518-F534 HydrophobicContact CZ-CE2 3.78Å; F518-F534 AromaticContact CZ-CZ 3.7Å; F518-F534 HydrophobicContact CZ-CZ 3.7Å; E528-F534 WeakPolarHBondContact O-CE2 3.33Å; H531-F534 HydrophobicContact CB-CD2 4.49Å; H531-F534 PolarHBondContact O-N 3.03Å; S532-F534 PolarHBondContact O-N 2.75Å; F534-Y537 WeakPolarHBondContact CA-O 3.3Å; F534-D539 HydrophobicContact CD1-CB 4.35Å; F534-D539 HydrophobicContact CE1-CB 4.42Å; F534-Y615 HydrophobicContact CE1-CD1 4.15Å; F534-Y615 HydrophobicContact CE1-CE1 4.12Å; F534-Y615 HydrophobicContact CZ-CD1 4.37Å; F534-Y615 HydrophobicContact CZ-CE1 4.05Å; F534-L617 HydrophobicContact CD1-CD2 4.49Å; F534-L617 HydrophobicContact CE1-CD1 4.19Å; F534-L617 HydrophobicContact CE1-CD2 4.08Å
535T96Very high97.2Very high106 Ų10645.9 Ų45.965%0.6524%0.237SC*.Hα-helixtrans-83.5-37.1169.2-54.20000111S532 L533S532-T535 VanDerWaalsContact O-CB 3.25Å; S532-T535 WeakPolarHBondContact O-CB 3.31Å; S532-T535 PolarHBondContact O-N 3.47Å; L533-T535 PolarHBondContact O-N 2.98Å
536H96.1Very high97.2Very high82 Ų8247.2 Ų47.238%0.3825%0.251SS..Hα-helixtrans-91.3-34-179.3-62.5-65.4000113.2S532 L533 T619 E621S532-H536 PolarHBondContact O-CD2 2.8Å; L533-H536 PolarHBondContact O-N 3.26Å; L533-H536 VanDerWaalsContact O-N 3.16Å; H536-T619 WeakPolarHBondContact O-CB 3.25Å; H536-T619 PolarHBondContact O-OG1 3.33Å; H536-E621 IonicContact CG-OE2 3.94Å; H536-E621 IonicContact ND1-OE1 3.99Å; H536-E621 IonicContact ND1-OE2 3.07Å; H536-E621 PolarHBondContact ND1-OE2 3.16Å
537Y98.2Very high97.3Very high21 Ų2147.2 Ų47.28%0.08225%0.252CS..SBendtrans-117.1118.1-179.5-72.5-94.7000110L488 D510 I512 L533 F534 Y618 T619L488-Y537 HydrophobicContact CD1-CE2 3.93Å; D510-Y537 VanDerWaalsContact CG-OH 3.25Å; D510-Y537 WeakPolarHBondContact OD1-CE1 3.29Å; D510-Y537 PolarHBondContact OD1-OH 2.78Å; D510-Y537 PolarHBondContact OD2-OH 3.05Å; D510-Y537 VanDerWaalsContact OD2-OH 3.14Å; I512-Y537 HydrophobicContact CD1-CD1 3.47Å; I512-Y537 VanDerWaalsContact CD1-CD1 3.47Å; I512-Y537 HydrophobicContact CD1-CD2 3.52Å; I512-Y537 HydrophobicContact CD1-CE1 3.51Å; I512-Y537 HydrophobicContact CD1-CE2 3.57Å; I512-Y537 HydrophobicContact CD1-CG 3.47Å; I512-Y537 VanDerWaalsContact CD1-CG 3.47Å; I512-Y537 HydrophobicContact CG1-CD1 3.76Å; I512-Y537 HydrophobicContact CG1-CE1 3.59Å; I512-Y537 HydrophobicContact CG1-CE2 4.48Å; I512-Y537 HydrophobicContact CG1-CG 4.27Å; L533-Y537 HydrophobicContact CD1-CD2 3.91Å; L533-Y537 HydrophobicContact CD1-CE2 4.48Å; L533-Y537 PolarHBondContact O-N 2.91Å; F534-Y537 WeakPolarHBondContact CA-O 3.3Å; Y537-Y618 CarbonylContact C-O 3.49Å; Y537-Y618 WeakPolarHBondContact CA-O 3.3Å; Y537-T619 HydrophobicContact CD1-CG2 4.13Å; Y537-T619 HydrophobicContact CE1-CG2 3.69Å
538K97.9Very high97.3Very high89 Ų8944 Ų4439%0.38724%0.236SC..BIsolated β-bridgetrans-78136.2-179.1-60.1-175.3-174.5-179.80110.4L617 Y618 E620K538-L617 WeakPolarHBondContact O-CA 3.4Å; K538-Y618 HydrophobicContact CB-CD1 4.25Å; K538-Y618 HydrophobicContact CB-CE1 3.79Å; K538-Y618 HydrophobicContact CD-CE2 4.39Å; K538-Y618 PolarHBondContact N-O 3.25Å; K538-Y618 PolarHBondContact O-N 3.4Å; K538-Y618 VanDerWaalsContact O-N 3.12Å; K538-E620 IonicContact NZ-OE1 3.94Å; K538-E620 PolarHBondContact NZ-OE1 2.9Å; K538-E620 IonicContact NZ-OE2 3.81Å; K538-E620 PolarHBondContact NZ-OE2 3.45Å
539D98.3Very high97.2Very high13 Ų1345.6 Ų45.67%0.0724%0.243CC..  trans-100.2114.2169.8-179.9-12000109.1F534 C541 R542 R612 Y615 L617F534-D539 HydrophobicContact CD1-CB 4.35Å; F534-D539 HydrophobicContact CE1-CB 4.42Å; D539-C541 PolarHBondContact O-N 2.92Å; D539-C541 VanDerWaalsContact O-N 3.15Å; D539-C541 WeakPolarHBondContact OD1-CB 3.23Å; D539-C541 PolarHBondContact OD1-N 3.13Å; D539-R542 HydrophobicContact CB-CB 3.65Å; D539-R542 PolarHBondContact O-N 3.3Å; D539-R542 VanDerWaalsContact O-N 3.13Å; D539-R612 IonicContact OD1-NH1 2.72Å; D539-R612 PolarHBondContact OD1-NH1 3.04Å; D539-R612 IonicContact OD1-NH2 3.78Å; D539-R612 IonicContact OD2-CZ 3.96Å; D539-R612 VanDerWaalsContact OD2-CZ 3.27Å; D539-R612 IonicContact OD2-NH1 3.68Å; D539-R612 PolarHBondContact OD2-NH1 3.35Å; D539-R612 IonicContact OD2-NH2 3.74Å; D539-R612 PolarHBondContact OD2-NH2 2.9Å; D539-Y615 WeakPolarHBondContact OD2-CD1 3.25Å; D539-Y615 WeakPolarHBondContact OD2-CE1 3.46Å; D539-L617 HydrophobicContact CB-CD2 3.52Å
540P97.9Very high97Very high7 Ų750.5 Ų50.55%0.04528%0.275CS..THydrogen-bonded Turntrans-58.1-26.9179.8-23.833.3000114.4F350 K549 W551 M616 Y618 V631 F634 M651F350-P540 HydrophobicContact CE2-CB 4.43Å; F350-P540 HydrophobicContact CZ-CB 3.84Å; P540-K549 VanDerWaalsContact O-CD 3.3Å; P540-K549 WeakPolarHBondContact O-CD 3.29Å; P540-K549 VanDerWaalsContact O-CE 3.32Å; P540-K549 WeakPolarHBondContact O-CE 3.48Å; P540-K549 PolarHBondContact O-NZ 3.32Å; P540-K549 VanDerWaalsContact O-NZ 3.1Å; P540-W551 WeakPolarHBondContact O-CZ2 3.21Å; P540-M616 VanDerWaalsContact CD-O 3.27Å; P540-M616 WeakPolarHBondContact CD-O 3.39Å; P540-Y618 HydrophobicContact CG-CD1 4.2Å; P540-Y618 HydrophobicContact CG-CE1 4.02Å; P540-V631 HydrophobicContact CG-CG2 4.12Å; P540-F634 HydrophobicContact CB-CD2 3.74Å; P540-F634 HydrophobicContact CB-CE2 4.01Å; P540-F634 HydrophobicContact CB-CG 4.48Å; P540-F634 HydrophobicContact CG-CD2 3.79Å; P540-F634 HydrophobicContact CG-CE2 3.84Å; P540-M651 HydrophobicContact CG-SD 3.76Å
541C97.9Very high96.9Very high0 Ų047.2 Ų47.20%026%0.258CS..THydrogen-bonded Turntrans-85.5-7.4-178.1-66.70000113.7D539 K549 W551 A552 F634D539-C541 PolarHBondContact O-N 2.92Å; D539-C541 VanDerWaalsContact O-N 3.15Å; D539-C541 WeakPolarHBondContact OD1-CB 3.23Å; D539-C541 PolarHBondContact OD1-N 3.13Å; C541-K549 WeakPolarHBondContact O-CB 3.44Å; C541-K549 PolarHBondContact O-N 3.08Å; C541-W551 HydrophobicContact CB-CH2 4.3Å; C541-W551 WeakPolarHBondContact SG-CH2 3.34Å; C541-A552 HydrophobicContact CB-CB 3.77Å; C541-F634 WeakPolarHBondContact SG-CE1 3.3Å; C541-F634 WeakPolarHBondContact SG-CZ 3.43Å
542R97.1Very high96.9Very high44 Ų4446.4 Ų46.417%0.16626%0.255CS..EExtended strand (participates in β ladder)trans-102.3136.5-167.8178.4171.6166.8137.8-5.1112.1N520 Q529 D539 G544N520-R542 PolarHBondContact OD1-NH1 2.87Å; Q529-R542 VanDerWaalsContact O-CZ 3.22Å; Q529-R542 PolarHBondContact O-NH1 3.05Å; Q529-R542 PolarHBondContact O-NH2 3.33Å; D539-R542 HydrophobicContact CB-CB 3.65Å; D539-R542 PolarHBondContact O-N 3.3Å; D539-R542 VanDerWaalsContact O-N 3.13Å; R542-G544 WeakPolarHBondContact CG-O 3.48Å
543I96.4Very high96.9Very high98 Ų9844.3 Ų44.350%0.50324%0.24SC..EExtended strand (participates in β ladder)trans-91.2-46.4163.3-62176.5000109.1E547 K549I543-E547 HydrophobicContact CB-CB 4.45Å; I543-E547 HydrophobicContact CB-CG 4.15Å; I543-E547 HydrophobicContact CD1-CG 4.26Å; I543-E547 PolarHBondContact N-O 2.95Å; I543-K549 HydrophobicContact CD1-CG 4.33Å; I543-K549 HydrophobicContact CG1-CB 4.41Å; I543-K549 HydrophobicContact CG1-CG 3.62Å
544G96.8Very high96.9Very high14 Ų1444.3 Ų44.314%0.14424%0.24CC..EExtended strand (participates in β ladder)trans-165.5-179.2-177.400000112.2N520 R542 G546 E547N520-G544 PolarHBondContact ND2-O 3.34Å; N520-G544 VanDerWaalsContact ND2-O 3.11Å; N520-G544 PolarHBondContact OD1-O 2.98Å; R542-G544 WeakPolarHBondContact CG-O 3.48Å; G544-G546 PolarHBondContact O-N 3.21Å; G544-E547 PolarHBondContact N-O 2.73Å; G544-E547 VanDerWaalsContact N-O 3.12Å; G544-E547 PolarHBondContact O-N 3.33Å; G544-E547 VanDerWaalsContact O-O 3.05Å
545P97.4Very high96.9Very high71 Ų7143.2 Ų43.246%0.46124%0.235SC..THydrogen-bonded Turntrans-62.4119.8176.825.8-32.6000110.6Q529 Q530 E547Q529-P545 HydrophobicContact CB-CB 4.08Å; Q530-P545 HydrophobicContact CG-CB 3.78Å; Q530-P545 HydrophobicContact CG-CG 4.32Å; P545-E547 VanDerWaalsContact C-N 3.28Å
546G95.5Very high97Very high30 Ų3039.4 Ų39.431%0.30921%0.21SC..THydrogen-bonded Turntrans79.28.8-177.800000114.3N520 Q529 G544N520-G546 CarbonylContact O-C 3.6Å; N520-G546 WeakPolarHBondContact O-CA 3.34Å; N520-G546 PolarHBondContact OD1-N 3.07Å; Q529-G546 VanDerWaalsContact OE1-CA 3.24Å; G544-G546 PolarHBondContact O-N 3.21Å
547E95.8Very high97Very high113 Ų11335.9 Ų35.953%0.52819%0.194SC..EExtended strand (participates in β ladder)trans-135.7107.6-179.3-166.7173-165.500111.8N520 I543 G544 P545N520-E547 PolarHBondContact ND2-O 2.64Å; N520-E547 PolarHBondContact O-N 2.93Å; I543-E547 HydrophobicContact CB-CB 4.45Å; I543-E547 HydrophobicContact CB-CG 4.15Å; I543-E547 HydrophobicContact CD1-CG 4.26Å; I543-E547 PolarHBondContact N-O 2.95Å; G544-E547 PolarHBondContact N-O 2.73Å; G544-E547 VanDerWaalsContact N-O 3.12Å; G544-E547 PolarHBondContact O-N 3.33Å; G544-E547 VanDerWaalsContact O-O 3.05Å; P545-E547 VanDerWaalsContact C-N 3.28Å
548D96.3Very high96.8Very high32 Ų3237.5 Ų37.517%0.17120%0.204CC..EExtended strand (participates in β ladder)trans-86.7152.8171.7-83.8-11.1000111.8N520 A552 R612N520-D548 WeakPolarHBondContact CB-OD1 3.42Å; N520-D548 PolarHBondContact ND2-OD1 2.95Å; D548-A552 HydrophobicContact CB-CB 4.12Å; D548-R612 IonicContact OD1-CZ 2.86Å; D548-R612 IonicContact OD1-NE 2.62Å; D548-R612 IonicContact OD1-NH2 3.42Å; D548-R612 PolarHBondContact OD1-NH2 2.79Å; D548-R612 IonicContact OD2-CZ 2.75Å; D548-R612 IonicContact OD2-NE 3.45Å; D548-R612 PolarHBondContact OD2-NE 2.95Å; D548-R612 IonicContact OD2-NH2 2.72Å
549K96.1Very high96.4Very high35 Ų3535.1 Ų35.115%0.15220%0.198CC..  trans-61.1150.4172-71.9-179174.3-175.80110.7E348 P540 C541 I543 W551 A552E348-K549 WeakPolarHBondContact OE1-CD 3.33Å; E348-K549 WeakPolarHBondContact OE1-CE 3.34Å; E348-K549 IonicContact OE1-NZ 2.63Å; E348-K549 PolarHBondContact OE1-NZ 3.14Å; E348-K549 IonicContact OE2-NZ 3.76Å; E348-K549 PolarHBondContact OE2-NZ 2.68Å; P540-K549 VanDerWaalsContact O-CD 3.3Å; P540-K549 WeakPolarHBondContact O-CD 3.29Å; P540-K549 VanDerWaalsContact O-CE 3.32Å; P540-K549 WeakPolarHBondContact O-CE 3.48Å; P540-K549 PolarHBondContact O-NZ 3.32Å; P540-K549 VanDerWaalsContact O-NZ 3.1Å; C541-K549 WeakPolarHBondContact O-CB 3.44Å; C541-K549 PolarHBondContact O-N 3.08Å; I543-K549 HydrophobicContact CD1-CG 4.33Å; I543-K549 HydrophobicContact CG1-CB 4.41Å; I543-K549 HydrophobicContact CG1-CG 3.62Å; K549-W551 HydrophobicContact CB-CG 4.5Å; K549-W551 HydrophobicContact CD-CZ2 3.84Å; K549-W551 PolarHBondContact O-N 3.06Å; K549-A552 WeakPolarHBondContact O-CB 3.2Å; K549-A552 PolarHBondContact O-N 3.25Å
550P94.5Very high96Very high109 Ų10941.5 Ų41.571%0.70823%0.227SC*.THydrogen-bonded Turntrans-58.5-26.6-174.1-26.334.8000115.2N609P550-N609 PolarHBondContact O-ND2 3.48Å
551W95.4Very high95.6Very high39 Ų3941.5 Ų41.515%0.14823%0.228CC..THydrogen-bonded Turntrans-87.4-16.3179.560.5-101.9000113.8E348 F350 H352 P540 C541 K549 F634 F636E348-W551 PolarHBondContact OE1-NE1 3.31Å; F350-W551 HydrophobicContact CE2-CH2 4.12Å; F350-W551 AromaticContact CE2-CZ2 3.91Å; F350-W551 HydrophobicContact CE2-CZ2 3.91Å; F350-W551 HydrophobicContact CZ-CH2 4.32Å; F350-W551 AromaticContact CZ-CZ2 3.82Å; F350-W551 HydrophobicContact CZ-CZ2 3.82Å; H352-W551 HydrophobicContact CB-CD2 3.99Å; H352-W551 HydrophobicContact CB-CE3 3.81Å; H352-W551 HydrophobicContact CB-CH2 4.23Å; H352-W551 HydrophobicContact CB-CZ2 4.38Å; H352-W551 HydrophobicContact CB-CZ3 3.94Å; H352-W551 AromaticContact CD2-CD1 3.81Å; H352-W551 AromaticContact CD2-CD2 3.99Å; H352-W551 AromaticContact CD2-CE2 3.97Å; H352-W551 AromaticContact CD2-CG 3.93Å; H352-W551 AromaticContact CD2-NE1 3.82Å; H352-W551 VanDerWaalsContact CE1-CB 3.49Å; H352-W551 WeakPolarHBondContact CE1-CB 3.16Å; H352-W551 AromaticContact CE1-CD1 3.84Å; H352-W551 AromaticContact CE1-CG 3.58Å; H352-W551 AromaticContact CG-CD2 3.64Å; H352-W551 AromaticContact CG-CE2 3.98Å; H352-W551 AromaticContact CG-CE3 3.92Å; H352-W551 AromaticContact CG-CG 3.82Å; H352-W551 AromaticContact ND1-CD2 3.81Å; H352-W551 AromaticContact ND1-CG 3.6Å; H352-W551 AromaticContact NE2-CD1 3.61Å; H352-W551 AromaticContact NE2-CG 3.79Å; P540-W551 WeakPolarHBondContact O-CZ2 3.21Å; C541-W551 HydrophobicContact CB-CH2 4.3Å; C541-W551 WeakPolarHBondContact SG-CH2 3.34Å; K549-W551 HydrophobicContact CB-CG 4.5Å; K549-W551 HydrophobicContact CD-CZ2 3.84Å; K549-W551 PolarHBondContact O-N 3.06Å; W551-F634 HydrophobicContact CH2-CB 4.26Å; W551-F634 AromaticContact CH2-CD1 3.93Å; W551-F634 HydrophobicContact CH2-CD1 3.93Å; W551-F634 HydrophobicContact CH2-CG 4.12Å; W551-F634 AromaticContact CZ3-CD1 3.8Å; W551-F634 HydrophobicContact CZ3-CD1 3.8Å; W551-F634 HydrophobicContact CZ3-CE1 4.34Å; W551-F634 HydrophobicContact CZ3-CG 4.4Å; W551-F636 AromaticContact CE3-CE2 3.99Å; W551-F636 HydrophobicContact CE3-CE2 3.99Å; W551-F636 AromaticContact CZ3-CE2 3.75Å; W551-F636 HydrophobicContact CZ3-CE2 3.75Å; W551-F636 HydrophobicContact CZ3-CZ 4.3Å
552A97.4Very high95.3Very high1 Ų141.9 Ų41.91%0.00823%0.23CC..  trans-71.1140.7179.400000110.2C541 D548 K549 N609 F636C541-A552 HydrophobicContact CB-CB 3.77Å; D548-A552 HydrophobicContact CB-CB 4.12Å; K549-A552 WeakPolarHBondContact O-CB 3.2Å; K549-A552 PolarHBondContact O-N 3.25Å; A552-N609 WeakPolarHBondContact O-CB 3.41Å; A552-N609 PolarHBondContact O-ND2 2.95Å; A552-F636 HydrophobicContact CB-CZ 4.29Å
553I98.1Very high95Very high4 Ų441.1 Ų41.12%0.02123%0.228CC..  trans-124159.8-178.867.3164000110.8I354 L577 R583 L587 N609 F636 L647I354-I553 HydrophobicContact CD1-CD1 3.82Å; I354-I553 HydrophobicContact CD1-CG2 4.47Å; I354-I553 HydrophobicContact CG1-CD1 3.96Å; I553-L577 HydrophobicContact CD1-CB 4.34Å; I553-L577 HydrophobicContact CD1-CD1 4.26Å; I553-R583 VanDerWaalsContact CG2-CD 3.46Å; I553-L587 HydrophobicContact CB-CD1 4.36Å; I553-N609 HydrophobicContact CB-CB 4.36Å; I553-N609 HydrophobicContact CG2-CB 4.2Å; I553-F636 HydrophobicContact CD1-CB 3.99Å; I553-F636 HydrophobicContact CD1-CD1 4.41Å; I553-F636 HydrophobicContact CD1-CD2 4.28Å; I553-F636 HydrophobicContact CD1-CG 3.99Å; I553-F636 HydrophobicContact CG1-CB 4.17Å; I553-F636 HydrophobicContact CG1-CD1 3.75Å; I553-F636 HydrophobicContact CG1-CD2 3.69Å; I553-F636 HydrophobicContact CG1-CE1 3.99Å; I553-F636 HydrophobicContact CG1-CE2 3.92Å; I553-F636 HydrophobicContact CG1-CG 3.59Å; I553-F636 HydrophobicContact CG1-CZ 4.07Å; I553-F636 WeakPolarHBondContact O-CE1 3.28Å; I553-L647 HydrophobicContact CD1-CD1 3.91Å
554G98.1Very high94.8Very high0 Ų038.5 Ų38.50%022%0.215CC..  trans-62.6150.4170.400000111.8L587 N609 R611G554-L587 WeakPolarHBondContact O-CD2 3.46Å; G554-N609 PolarHBondContact N-O 3.35Å; G554-R611 CarbonylContact C-O 3.49Å; G554-R611 WeakPolarHBondContact CA-O 3.4Å
555T98.5Very high94.5Very high0 Ų045.5 Ų45.50%024%0.244CC..  trans-109.4-15.6-177.755.90000112.4R611 R612 I613 D614 F636 H646 L647 V649T555-R611 PolarHBondContact N-O 3.36Å; T555-R612 HydrophobicContact CG2-CG 3.98Å; T555-I613 PolarHBondContact OG1-N 3.06Å; T555-D614 WeakPolarHBondContact CB-OD2 3.44Å; T555-D614 HydrophobicContact CG2-CB 4.17Å; T555-D614 PolarHBondContact OG1-N 3.43Å; T555-D614 VanDerWaalsContact OG1-N 3.14Å; T555-D614 PolarHBondContact OG1-OD2 2.64Å; T555-F636 HydrophobicContact CG2-CD1 3.92Å; T555-F636 HydrophobicContact CG2-CE1 3.91Å; T555-H646 CarbonylContact O-C 3.46Å; T555-H646 WeakPolarHBondContact O-CA 3.24Å; T555-L647 PolarHBondContact O-N 3.18Å; T555-V649 HydrophobicContact CG2-CG2 3.67Å
556L97.4Very high94.1Very high26 Ų2648 Ų4814%0.13625%0.25CC..BIsolated β-bridgetrans-88.9117.2175.1-174.763.8000110.7L587 V588 R611 I613L556-L587 WeakPolarHBondContact O-CA 3.32Å; L556-V588 HydrophobicContact CB-CB 4.29Å; L556-V588 HydrophobicContact CB-CG2 4.42Å; L556-V588 HydrophobicContact CD2-CB 3.86Å; L556-V588 HydrophobicContact CD2-CG1 4.04Å; L556-V588 HydrophobicContact CD2-CG2 3.84Å; L556-V588 HydrophobicContact CG-CB 3.99Å; L556-V588 HydrophobicContact CG-CG2 3.71Å; L556-V588 PolarHBondContact O-N 3.14Å; L556-R611 PolarHBondContact N-O 3.28Å; L556-I613 HydrophobicContact CB-CD1 4.05Å; L556-I613 HydrophobicContact CB-CG1 4.34Å; L556-I613 HydrophobicContact CD1-CD1 4.31Å; L556-I613 HydrophobicContact CD2-CD1 4.07Å; L556-I613 HydrophobicContact CG-CD1 4.38Å
557L96.4Very high93.9Very high8 Ų846.9 Ų46.94%0.04224%0.236CC..BIsolated β-bridgetrans-79.5145.9175.5-64.8163000110.2P559 L562 L573 Y586 L587 V588 D645 L647L557-P559 WeakPolarHBondContact O-CD 3.35Å; L557-L562 HydrophobicContact CD1-CD1 4.18Å; L557-L573 HydrophobicContact CD1-CD2 4.39Å; L557-L573 HydrophobicContact CD2-CD1 4.06Å; L557-L573 HydrophobicContact CD2-CD2 4.4Å; L557-Y586 CarbonylContact C-O 2.94Å; L557-Y586 WeakPolarHBondContact CA-O 3.23Å; L557-L587 HydrophobicContact CD2-CD2 3.99Å; L557-V588 WeakPolarHBondContact O-CG2 3.21Å; L557-D645 VanDerWaalsContact CB-O 3.29Å; L557-D645 WeakPolarHBondContact CB-O 3.19Å; L557-D645 PolarHBondContact N-O 3.05Å; L557-L647 HydrophobicContact CD1-CD2 4.11Å; L557-L647 HydrophobicContact CD2-CD2 4.14Å; L557-L647 HydrophobicContact CD2-CG 4.4Å; L557-L647 HydrophobicContact CG-CD2 4.28Å; L557-L647 HydrophobicContact CG-CG 4.37Å
558D94.1Very high93.5Very high55 Ų5543.1 Ų43.129%0.29422%0.222SC..  trans-68.3115.1169.4-173.9-16.9000108.9E560 G561 Y586 V588D558-E560 PolarHBondContact O-N 3.34Å; D558-E560 VanDerWaalsContact O-N 3.14Å; D558-E560 PolarHBondContact OD1-N 3.03Å; D558-G561 PolarHBondContact O-N 2.79Å; D558-Y586 PolarHBondContact N-O 3.34Å; D558-V588 HydrophobicContact CB-CG2 4.48Å
559P90.1Very high93.5Very high38 Ų3843 Ų4325%0.24722%0.223CC..G310 helixtrans-58.8-30.2-176.8-24.735.5000112.5N143 L557 G561 L562N143-P559 HydrophobicContact CB-CB 3.73Å; N143-P559 PolarHBondContact ND2-O 2.76Å; L557-P559 WeakPolarHBondContact O-CD 3.35Å; P559-G561 VanDerWaalsContact C-N 3.28Å; P559-G561 PolarHBondContact O-N 2.84Å; P559-L562 WeakPolarHBondContact O-CB 3.35Å; P559-L562 PolarHBondContact O-N 2.9Å
560E89.3Confident93.5Very high147 Ų14742.7 Ų42.769%0.68722%0.224SC*.G310 helixtrans-61.8-36.5-176.8-67-166171.200112.8T42 D558T42-E560 PolarHBondContact OG1-O 2.81Å; D558-E560 PolarHBondContact O-N 3.34Å; D558-E560 VanDerWaalsContact O-N 3.14Å; D558-E560 PolarHBondContact OD1-N 3.03Å
561G89.5Confident93.7Very high7 Ų741.1 Ų41.17%0.07221%0.21CC..G310 helixtrans-90.50.9-176.700000115D558 P559 Y563 D564 V567D558-G561 PolarHBondContact O-N 2.79Å; P559-G561 VanDerWaalsContact C-N 3.28Å; P559-G561 PolarHBondContact O-N 2.84Å; G561-Y563 PolarHBondContact O-N 3.37Å; G561-D564 PolarHBondContact O-N 3.43Å; G561-D564 VanDerWaalsContact O-N 3.08Å; G561-V567 WeakPolarHBondContact O-CG2 3.31Å
562L90.8Very high93.7Very high8 Ų841.8 Ų41.84%0.04222%0.216CC..THydrogen-bonded Turntrans-58.1-24.8-170.4-171.162.7000114.5V144 L557 P559 T644V144-L562 HydrophobicContact CG1-CD2 3.35Å; L557-L562 HydrophobicContact CD1-CD1 4.18Å; P559-L562 WeakPolarHBondContact O-CB 3.35Å; P559-L562 PolarHBondContact O-N 2.9Å; L562-T644 WeakPolarHBondContact CD1-O 3.3Å
563Y91.5Very high93.8Very high29 Ų2942 Ų4211%0.11422%0.217CC..THydrogen-bonded Turntrans-113.215.5-177.2-56.3-64.5000113.8T42 Y43 R46 N143 V144 F145 G561T42-Y563 WeakPolarHBondContact OG1-CD2 3.49Å; Y43-Y563 HydrophobicContact CD2-CG 4.44Å; R46-Y563 PolarHBondContact NH1-O 3.02Å; N143-Y563 WeakPolarHBondContact O-CE2 3.44Å; N143-Y563 PolarHBondContact O-OH 3.08Å; V144-Y563 WeakPolarHBondContact CA-OH 3.41Å; F145-Y563 WeakPolarHBondContact CD1-OH 3.34Å; F145-Y563 HydrophobicContact CE1-CE1 4.38Å; F145-Y563 AromaticContact CE1-CZ 3.99Å; G561-Y563 PolarHBondContact O-N 3.37Å
564D92.6Very high93.8Very high42 Ų4243.6 Ų43.623%0.22523%0.225CC..  trans-69.4140.2172.1-66.2-16.1000110R46 G561 E566 V567 C568 Y586R46-D564 IonicContact CZ-OD1 3.65Å; R46-D564 IonicContact NH1-OD1 3.78Å; R46-D564 IonicContact NH2-OD1 2.66Å; R46-D564 PolarHBondContact NH2-OD1 2.99Å; G561-D564 PolarHBondContact O-N 3.43Å; G561-D564 VanDerWaalsContact O-N 3.08Å; D564-E566 PolarHBondContact O-N 3.07Å; D564-E566 VanDerWaalsContact O-N 3.12Å; D564-V567 HydrophobicContact CB-CG2 4.04Å; D564-V567 WeakPolarHBondContact O-CG2 3.46Å; D564-V567 PolarHBondContact O-N 3.34Å; D564-C568 WeakPolarHBondContact O-CB 3.24Å; D564-C568 PolarHBondContact O-N 3.21Å; D564-Y586 HydrophobicContact CB-CE1 3.94Å; D564-Y586 PolarHBondContact OD2-OH 2.73Å
565E89.6Confident93.7Very high161 Ų16150.1 Ų50.175%0.75225%0.253SS*.THydrogen-bonded Turntrans-59.4-28.4-176.7-63.5-174.6169.100112.4V567 N572E565-V567 PolarHBondContact O-N 3.42Å; E565-N572 PolarHBondContact O-ND2 3.39Å
566E90.1Very high93.7Very high125 Ų12551.1 Ų51.158%0.58426%0.259SS*.THydrogen-bonded Turntrans-69.5-13.4176.8-58.8-179.7168.900113.6D564 N572 V576 Y586D564-E566 PolarHBondContact O-N 3.07Å; D564-E566 VanDerWaalsContact O-N 3.12Å; E566-N572 CarbonylContact O-C 3.57Å; E566-N572 VanDerWaalsContact O-CB 3.27Å; E566-N572 WeakPolarHBondContact O-CB 3.2Å; E566-V576 VanDerWaalsContact O-CG2 3.27Å; E566-V576 WeakPolarHBondContact O-CG2 3.32Å; E566-Y586 PolarHBondContact OE2-OH 3.16Å
567V90.4Very high93.7Very high5 Ų549.9 Ų49.93%0.0325%0.252CS..THydrogen-bonded Turntrans-136-5.8-176.6-63.50000114.7G561 D564 E565 T569 L573 V576 Y586G561-V567 WeakPolarHBondContact O-CG2 3.31Å; D564-V567 HydrophobicContact CB-CG2 4.04Å; D564-V567 WeakPolarHBondContact O-CG2 3.46Å; D564-V567 PolarHBondContact O-N 3.34Å; E565-V567 PolarHBondContact O-N 3.42Å; V567-T569 PolarHBondContact O-N 2.83Å; V567-T569 VanDerWaalsContact O-N 3.12Å; V567-L573 HydrophobicContact CB-CB 4.39Å; V567-L573 HydrophobicContact CB-CD1 3.96Å; V567-L573 HydrophobicContact CG1-CD1 3.96Å; V567-V576 HydrophobicContact CG1-CB 4.08Å; V567-V576 HydrophobicContact CG1-CG1 3.91Å; V567-V576 HydrophobicContact CG1-CG2 3.9Å; V567-Y586 HydrophobicContact CB-CD1 4.28Å; V567-Y586 HydrophobicContact CB-CE1 4.15Å; V567-Y586 HydrophobicContact CG1-CD1 3.63Å; V567-Y586 HydrophobicContact CG1-CD2 3.83Å; V567-Y586 HydrophobicContact CG1-CE1 3.52Å; V567-Y586 HydrophobicContact CG1-CE2 3.71Å; V567-Y586 HydrophobicContact CG1-CG 3.77Å; V567-Y586 HydrophobicContact CG2-CD1 3.81Å; V567-Y586 HydrophobicContact CG2-CE1 3.5Å
568C87.6Confident93.7Very high34 Ų3453.7 Ų53.723%0.2327%0.27CS..SBendtrans-71.1-8.5-17469.10000114.8D564D564-C568 WeakPolarHBondContact O-CB 3.24Å; D564-C568 PolarHBondContact O-N 3.21Å
569T95.4Very high93.7Very high30 Ų3053.1 Ų53.118%0.18427%0.271CS..SBendtrans-115.6150.7175.173.30000111.4V567 D571 N572 L573V567-T569 PolarHBondContact O-N 2.83Å; V567-T569 VanDerWaalsContact O-N 3.12Å; T569-D571 VanDerWaalsContact C-N 3.33Å; T569-D571 PolarHBondContact O-N 3.02Å; T569-N572 PolarHBondContact O-N 3.41Å; T569-N572 VanDerWaalsContact O-N 3.16Å; T569-N572 VanDerWaalsContact OG1-CB 3.23Å; T569-N572 WeakPolarHBondContact OG1-CB 3.2Å; T569-N572 PolarHBondContact OG1-N 3.42Å; T569-N572 PolarHBondContact OG1-ND2 2.75Å; T569-L573 PolarHBondContact O-N 2.98Å
570P97.2Very high93.9Very high28 Ų2855.5 Ų55.518%0.18228%0.279CS..Hα-helixtrans-53.5-45.5179.5-31.238.4000114.6A356 Q574 T638A356-P570 HydrophobicContact CB-CB 4.11Å; P570-Q574 WeakPolarHBondContact O-CB 3.35Å; P570-Q574 PolarHBondContact O-N 2.7Å; P570-T638 WeakPolarHBondContact CA-O 3.12Å; P570-T638 PolarHBondContact O-OG1 3.25Å
571D97.5Very high94Very high76 Ų7655.1 Ų55.141%0.40628%0.277SS..Hα-helixtrans-68.9-35.3-179.1-68.2-34.6000112.1A356 T569 K575A356-D571 WeakPolarHBondContact CB-OD1 3.5Å; T569-D571 VanDerWaalsContact C-N 3.33Å; T569-D571 PolarHBondContact O-N 3.02Å; D571-K575 VanDerWaalsContact O-CG 3.28Å; D571-K575 WeakPolarHBondContact O-CG 3.32Å; D571-K575 PolarHBondContact O-N 3.22Å; D571-K575 VanDerWaalsContact O-N 3.14Å
572N97.2Very high94.2Very high53 Ų5355.3 Ų55.328%0.28328%0.278SS..Hα-helixtrans-71.4-47.6178.4-70.7-5.6000110.5E565 E566 T569 Q574 K575 V576E565-N572 PolarHBondContact O-ND2 3.39Å; E566-N572 CarbonylContact O-C 3.57Å; E566-N572 VanDerWaalsContact O-CB 3.27Å; E566-N572 WeakPolarHBondContact O-CB 3.2Å; T569-N572 PolarHBondContact O-N 3.41Å; T569-N572 VanDerWaalsContact O-N 3.16Å; T569-N572 VanDerWaalsContact OG1-CB 3.23Å; T569-N572 WeakPolarHBondContact OG1-CB 3.2Å; T569-N572 PolarHBondContact OG1-N 3.42Å; T569-N572 PolarHBondContact OG1-ND2 2.75Å; N572-Q574 VanDerWaalsContact C-N 3.28Å; N572-Q574 PolarHBondContact O-N 2.85Å; N572-K575 PolarHBondContact O-N 3.48Å; N572-K575 VanDerWaalsContact O-N 3.15Å; N572-V576 WeakPolarHBondContact O-CG2 3.36Å; N572-V576 PolarHBondContact O-N 2.84Å
573L97.9Very high94.5Very high5 Ų556.3 Ų56.33%0.02628%0.282CS..Hα-helixtrans-59.7-39.4175.4-177.859.1000111.6L557 V567 T569 V576 L577 T638 A641 L647L557-L573 HydrophobicContact CD1-CD2 4.39Å; L557-L573 HydrophobicContact CD2-CD1 4.06Å; L557-L573 HydrophobicContact CD2-CD2 4.4Å; V567-L573 HydrophobicContact CB-CB 4.39Å; V567-L573 HydrophobicContact CB-CD1 3.96Å; V567-L573 HydrophobicContact CG1-CD1 3.96Å; T569-L573 PolarHBondContact O-N 2.98Å; L573-V576 PolarHBondContact O-N 3.26Å; L573-L577 HydrophobicContact CD1-CD1 3.78Å; L573-L577 HydrophobicContact CD1-CD2 4.26Å; L573-L577 HydrophobicContact CD1-CG 3.8Å; L573-L577 HydrophobicContact CG-CD1 3.85Å; L573-L577 HydrophobicContact CG-CG 4.25Å; L573-L577 WeakPolarHBondContact O-CB 3.43Å; L573-L577 VanDerWaalsContact O-CG 3.25Å; L573-L577 WeakPolarHBondContact O-CG 3.36Å; L573-L577 PolarHBondContact O-N 3.36Å; L573-T638 HydrophobicContact CB-CG2 4.22Å; L573-T638 HydrophobicContact CD2-CG2 4.03Å; L573-T638 HydrophobicContact CG-CG2 3.76Å; L573-A641 HydrophobicContact CB-CB 4.16Å; L573-A641 HydrophobicContact CD2-CB 3.78Å; L573-L647 HydrophobicContact CD2-CD2 4Å
574Q98.3Very high94.5Very high39 Ų3956.9 Ų56.918%0.18228%0.284CS..Hα-helixtrans-56.1-53.7173.4-177.7-173.73300111.2I354 P570 N572 V576 L577 E578 T638I354-Q574 HydrophobicContact CG2-CG 4.12Å; I354-Q574 PolarHBondContact O-NE2 2.89Å; P570-Q574 WeakPolarHBondContact O-CB 3.35Å; P570-Q574 PolarHBondContact O-N 2.7Å; N572-Q574 VanDerWaalsContact C-N 3.28Å; N572-Q574 PolarHBondContact O-N 2.85Å; Q574-V576 VanDerWaalsContact C-N 3.3Å; Q574-V576 PolarHBondContact O-N 3.35Å; Q574-L577 PolarHBondContact O-N 3.24Å; Q574-E578 WeakPolarHBondContact O-CG 2.99Å; Q574-E578 PolarHBondContact O-N 3.36Å; Q574-T638 HydrophobicContact CB-CG2 4.39Å
575K97.4Very high94.5Very high136 Ų13655.8 Ų55.859%0.59128%0.283SS*.Hα-helixtrans-59.6-40.9-179.9-70.7167.2-170.1165.20112.3D571 N572D571-K575 VanDerWaalsContact O-CG 3.28Å; D571-K575 WeakPolarHBondContact O-CG 3.32Å; D571-K575 PolarHBondContact O-N 3.22Å; D571-K575 VanDerWaalsContact O-N 3.14Å; N572-K575 PolarHBondContact O-N 3.48Å; N572-K575 VanDerWaalsContact O-N 3.15Å
576V97Very high94.7Very high21 Ų2149.2 Ų49.213%0.12725%0.252CS..Hα-helixtrans-63.1-49.3178.5167.70000110.4E566 V567 N572 L573 Q574 E578 S579 G582 Y586E566-V576 VanDerWaalsContact O-CG2 3.27Å; E566-V576 WeakPolarHBondContact O-CG2 3.32Å; V567-V576 HydrophobicContact CG1-CB 4.08Å; V567-V576 HydrophobicContact CG1-CG1 3.91Å; V567-V576 HydrophobicContact CG1-CG2 3.9Å; N572-V576 WeakPolarHBondContact O-CG2 3.36Å; N572-V576 PolarHBondContact O-N 2.84Å; L573-V576 PolarHBondContact O-N 3.26Å; Q574-V576 VanDerWaalsContact C-N 3.3Å; Q574-V576 PolarHBondContact O-N 3.35Å; V576-E578 VanDerWaalsContact C-N 3.28Å; V576-E578 PolarHBondContact O-N 2.67Å; V576-S579 PolarHBondContact O-N 2.64Å; V576-S579 VanDerWaalsContact O-N 3.07Å; V576-S579 PolarHBondContact O-OG 2.9Å; V576-G582 WeakPolarHBondContact O-CA 3.11Å; V576-Y586 HydrophobicContact CG1-CD2 3.41Å; V576-Y586 VanDerWaalsContact CG1-CD2 3.41Å; V576-Y586 HydrophobicContact CG1-CE2 3.82Å; V576-Y586 HydrophobicContact CG1-CG 4.23Å
577L97.5Very high95Very high0 Ų043.5 Ų43.50%023%0.225CC..Hα-helixtrans-71.9-19.4-176.7-63.9178.6000113.8I354 I553 L573 Q574 S579 R583 L587 T638 L647I354-L577 HydrophobicContact CD1-CB 3.91Å; I354-L577 WeakPolarHBondContact CD1-O 3.46Å; I354-L577 HydrophobicContact CG2-CB 4.4Å; I553-L577 HydrophobicContact CD1-CB 4.34Å; I553-L577 HydrophobicContact CD1-CD1 4.26Å; L573-L577 HydrophobicContact CD1-CD1 3.78Å; L573-L577 HydrophobicContact CD1-CD2 4.26Å; L573-L577 HydrophobicContact CD1-CG 3.8Å; L573-L577 HydrophobicContact CG-CD1 3.85Å; L573-L577 HydrophobicContact CG-CG 4.25Å; L573-L577 WeakPolarHBondContact O-CB 3.43Å; L573-L577 VanDerWaalsContact O-CG 3.25Å; L573-L577 WeakPolarHBondContact O-CG 3.36Å; L573-L577 PolarHBondContact O-N 3.36Å; Q574-L577 PolarHBondContact O-N 3.24Å; L577-S579 PolarHBondContact O-N 3.35Å; L577-R583 HydrophobicContact CB-CG 4.49Å; L577-R583 HydrophobicContact CD2-CG 4.22Å; L577-R583 WeakPolarHBondContact O-CD 3.28Å; L577-R583 WeakPolarHBondContact O-CG 3.21Å; L577-R583 PolarHBondContact O-NH1 2.92Å; L577-L587 HydrophobicContact CD2-CD1 4.07Å; L577-L587 HydrophobicContact CD2-CD2 3.89Å; L577-L587 HydrophobicContact CD2-CG 3.77Å; L577-T638 HydrophobicContact CD1-CG2 3.88Å; L577-L647 HydrophobicContact CD1-CD1 3.55Å; L577-L647 HydrophobicContact CD1-CD2 4.01Å; L577-L647 HydrophobicContact CD1-CG 4.42Å
578E96.3Very high95.2Very high88 Ų8845 Ų4541%0.41123%0.234SC..Hα-helixtrans-65.9-26.7169.5-77.2-170.3-149.100112.7K342 I354 Q574 V576 R583K342-E578 IonicContact NZ-OE2 2.85Å; K342-E578 PolarHBondContact NZ-OE2 3.17Å; I354-E578 HydrophobicContact CD1-CG 4.18Å; Q574-E578 WeakPolarHBondContact O-CG 2.99Å; Q574-E578 PolarHBondContact O-N 3.36Å; V576-E578 VanDerWaalsContact C-N 3.28Å; V576-E578 PolarHBondContact O-N 2.67Å; E578-R583 PolarHBondContact O-NH1 3.26Å; E578-R583 VanDerWaalsContact O-NH1 3.14Å
579S95.1Very high95.4Very high44 Ų4444.2 Ų44.231%0.30823%0.227SC..SBendtrans-90.7143.6177.373.30000112.3V576 L577 E581 G582 R583V576-S579 PolarHBondContact O-N 2.64Å; V576-S579 VanDerWaalsContact O-N 3.07Å; V576-S579 PolarHBondContact O-OG 2.9Å; L577-S579 PolarHBondContact O-N 3.35Å; S579-E581 VanDerWaalsContact C-N 3.33Å; S579-G582 PolarHBondContact O-N 3.04Å; S579-G582 WeakPolarHBondContact OG-CA 3.17Å; S579-G582 PolarHBondContact OG-N 3.27Å; S579-R583 WeakPolarHBondContact O-CG 2.93Å; S579-R583 PolarHBondContact O-N 2.85Å; S579-R583 PolarHBondContact O-NH1 3.36Å
580E93.5Very high94.9Very high88 Ų8844.8 Ų44.841%0.41123%0.23SC..Hα-helixtrans-66.2-38.4177.4-172.1-175.6157.600111.4R583 K584E580-R583 PolarHBondContact O-N 3.1Å; E580-K584 HydrophobicContact CG-CD 4.5Å; E580-K584 WeakPolarHBondContact O-CG 3.49Å; E580-K584 PolarHBondContact O-N 3.29Å; E580-K584 WeakPolarHBondContact OE1-CE 3.41Å; E580-K584 IonicContact OE1-NZ 3.5Å; E580-K584 PolarHBondContact OE1-NZ 2.85Å
581E92.1Very high93.7Very high139 Ų13948.9 Ų48.965%0.6526%0.255SS*.Hα-helixtrans-64.2-41.7177.4-6470.7-154.600111.5S579 K584 G585S579-E581 VanDerWaalsContact C-N 3.33Å; E581-K584 PolarHBondContact O-N 2.95Å; E581-G585 PolarHBondContact O-N 3.12Å
582G93.9Very high91.8Very high10 Ų1048.8 Ų48.810%0.10326%0.261CS..Hα-helixtrans-65.3-43.6175.300000111.9V576 S579 K584 G585 Y586V576-G582 WeakPolarHBondContact O-CA 3.11Å; S579-G582 PolarHBondContact O-N 3.04Å; S579-G582 WeakPolarHBondContact OG-CA 3.17Å; S579-G582 PolarHBondContact OG-N 3.27Å; G582-K584 PolarHBondContact O-N 2.75Å; G582-G585 WeakPolarHBondContact O-CA 3.29Å; G582-G585 PolarHBondContact O-N 2.99Å; G582-Y586 WeakPolarHBondContact O-CD2 3.32Å; G582-Y586 PolarHBondContact O-N 3.31Å
583R95.6Very high89.7Confident30 Ų3054.3 Ų54.311%0.11328%0.282CS..Hα-helixtrans-56.9-47.3172.6-71.9-166.8-60.2-81.35112I553 L577 E578 S579 E580 G585 Y586 L587 N609I553-R583 VanDerWaalsContact CG2-CD 3.46Å; L577-R583 HydrophobicContact CB-CG 4.49Å; L577-R583 HydrophobicContact CD2-CG 4.22Å; L577-R583 WeakPolarHBondContact O-CD 3.28Å; L577-R583 WeakPolarHBondContact O-CG 3.21Å; L577-R583 PolarHBondContact O-NH1 2.92Å; E578-R583 PolarHBondContact O-NH1 3.26Å; E578-R583 VanDerWaalsContact O-NH1 3.14Å; S579-R583 WeakPolarHBondContact O-CG 2.93Å; S579-R583 PolarHBondContact O-N 2.85Å; S579-R583 PolarHBondContact O-NH1 3.36Å; E580-R583 PolarHBondContact O-N 3.1Å; R583-G585 PolarHBondContact O-N 3.21Å; R583-Y586 PolarHBondContact O-N 2.94Å; R583-L587 HydrophobicContact CB-CD1 3.93Å; R583-L587 HydrophobicContact CG-CD1 3.84Å; R583-L587 WeakPolarHBondContact O-CB 3.33Å; R583-L587 PolarHBondContact O-N 3.3Å; R583-N609 PolarHBondContact NE-OD1 2.97Å; R583-N609 VanDerWaalsContact NE-OD1 3.12Å; R583-N609 PolarHBondContact NH2-OD1 3Å
584K92.6Very high87Confident40 Ų4061 Ų6117%0.17432%0.318CS..Hα-helixtrans-63.6-20.3174.9-71.2174.6-175.4168.90114.2E580 E581 G582 Y589 L606E580-K584 HydrophobicContact CG-CD 4.5Å; E580-K584 WeakPolarHBondContact O-CG 3.49Å; E580-K584 PolarHBondContact O-N 3.29Å; E580-K584 WeakPolarHBondContact OE1-CE 3.41Å; E580-K584 IonicContact OE1-NZ 3.5Å; E580-K584 PolarHBondContact OE1-NZ 2.85Å; E581-K584 PolarHBondContact O-N 2.95Å; G582-K584 PolarHBondContact O-N 2.75Å; K584-Y589 HydrophobicContact CB-CE2 4.5Å; K584-Y589 HydrophobicContact CG-CE2 4.25Å; K584-L606 HydrophobicContact CB-CD1 4.35Å; K584-L606 HydrophobicContact CD-CB 4.48Å; K584-L606 WeakPolarHBondContact CE-O 3.07Å; K584-L606 HydrophobicContact CG-CB 4.29Å; K584-L606 HydrophobicContact CG-CD1 4.42Å
585G91.3Very high84.3Confident19 Ų1964.7 Ų64.720%0.19634%0.335CS..Hα-helixtrans-86.7-31.717900000114.1E581 G582 R583E581-G585 PolarHBondContact O-N 3.12Å; G582-G585 WeakPolarHBondContact O-CA 3.29Å; G582-G585 PolarHBondContact O-N 2.99Å; R583-G585 PolarHBondContact O-N 3.21Å
586Y95.4Very high81.1Confident23 Ų2362 Ų629%0.0933%0.333CS..Hα-helixtrans-131.7-6.2-165.4-68.4-83000115.2L557 D558 D564 E566 V567 V576 G582 R583L557-Y586 CarbonylContact C-O 2.94Å; L557-Y586 WeakPolarHBondContact CA-O 3.23Å; D558-Y586 PolarHBondContact N-O 3.34Å; D564-Y586 HydrophobicContact CB-CE1 3.94Å; D564-Y586 PolarHBondContact OD2-OH 2.73Å; E566-Y586 PolarHBondContact OE2-OH 3.16Å; V567-Y586 HydrophobicContact CB-CD1 4.28Å; V567-Y586 HydrophobicContact CB-CE1 4.15Å; V567-Y586 HydrophobicContact CG1-CD1 3.63Å; V567-Y586 HydrophobicContact CG1-CD2 3.83Å; V567-Y586 HydrophobicContact CG1-CE1 3.52Å; V567-Y586 HydrophobicContact CG1-CE2 3.71Å; V567-Y586 HydrophobicContact CG1-CG 3.77Å; V567-Y586 HydrophobicContact CG2-CD1 3.81Å; V567-Y586 HydrophobicContact CG2-CE1 3.5Å; V576-Y586 HydrophobicContact CG1-CD2 3.41Å; V576-Y586 VanDerWaalsContact CG1-CD2 3.41Å; V576-Y586 HydrophobicContact CG1-CE2 3.82Å; V576-Y586 HydrophobicContact CG1-CG 4.23Å; G582-Y586 WeakPolarHBondContact O-CD2 3.32Å; G582-Y586 PolarHBondContact O-N 3.31Å; R583-Y586 PolarHBondContact O-N 2.94Å
587L95.9Very high78.1Confident6 Ų667.5 Ų67.53%0.03137%0.372CS..BIsolated β-bridgetrans-101147.3169.7-62.4177.1000110.4I553 G554 L556 L557 L577 R583 Y589 N609 L647I553-L587 HydrophobicContact CB-CD1 4.36Å; G554-L587 WeakPolarHBondContact O-CD2 3.46Å; L556-L587 WeakPolarHBondContact O-CA 3.32Å; L557-L587 HydrophobicContact CD2-CD2 3.99Å; L577-L587 HydrophobicContact CD2-CD1 4.07Å; L577-L587 HydrophobicContact CD2-CD2 3.89Å; L577-L587 HydrophobicContact CD2-CG 3.77Å; R583-L587 HydrophobicContact CB-CD1 3.93Å; R583-L587 HydrophobicContact CG-CD1 3.84Å; R583-L587 WeakPolarHBondContact O-CB 3.33Å; R583-L587 PolarHBondContact O-N 3.3Å; L587-Y589 HydrophobicContact CB-CE2 4.28Å; L587-Y589 WeakPolarHBondContact O-CD2 3.3Å; L587-N609 WeakPolarHBondContact CD1-O 3.32Å; L587-L647 HydrophobicContact CD2-CD1 4.23Å
588V93.9Very high75.2Confident35 Ų3572.1 Ų72.121%0.21241%0.405CS..  trans-71.5134.6171179.10000109.2L556 L557 D558 G610 R611L556-V588 HydrophobicContact CB-CB 4.29Å; L556-V588 HydrophobicContact CB-CG2 4.42Å; L556-V588 HydrophobicContact CD2-CB 3.86Å; L556-V588 HydrophobicContact CD2-CG1 4.04Å; L556-V588 HydrophobicContact CD2-CG2 3.84Å; L556-V588 HydrophobicContact CG-CB 3.99Å; L556-V588 HydrophobicContact CG-CG2 3.71Å; L556-V588 PolarHBondContact O-N 3.14Å; L557-V588 WeakPolarHBondContact O-CG2 3.21Å; D558-V588 HydrophobicContact CB-CG2 4.48Å; V588-G610 CarbonylContact O-C 3.5Å; V588-G610 WeakPolarHBondContact O-CA 3.36Å; V588-R611 WeakPolarHBondContact O-CG 3.35Å; V588-R611 PolarHBondContact O-N 3.39Å
589Y92Very high72.3Confident19 Ų1974.3 Ų74.38%0.07542%0.415CS..  trans-113.3156.5174.3-82.9-103.4000110.9K584 L587 T591 L606 G608 G610K584-Y589 HydrophobicContact CB-CE2 4.5Å; K584-Y589 HydrophobicContact CG-CE2 4.25Å; L587-Y589 HydrophobicContact CB-CE2 4.28Å; L587-Y589 WeakPolarHBondContact O-CD2 3.3Å; Y589-T591 PolarHBondContact O-N 2.9Å; Y589-L606 HydrophobicContact CD1-CB 3.81Å; Y589-L606 HydrophobicContact CD1-CD1 4.48Å; Y589-L606 HydrophobicContact CD1-CD2 4.33Å; Y589-L606 HydrophobicContact CD1-CG 4.42Å; Y589-L606 HydrophobicContact CD2-CD1 4.01Å; Y589-L606 HydrophobicContact CE1-CB 3.97Å; Y589-L606 HydrophobicContact CE2-CD1 4.48Å; Y589-L606 HydrophobicContact CG-CB 4.18Å; Y589-L606 HydrophobicContact CG-CD1 4.02Å; Y589-L606 HydrophobicContact CG-CD2 4.11Å; Y589-L606 HydrophobicContact CG-CG 4.32Å; Y589-G608 VanDerWaalsContact CE1-O 3.23Å; Y589-G608 WeakPolarHBondContact CE1-O 3.42Å; Y589-G608 PolarHBondContact OH-O 2.89Å; Y589-G610 VanDerWaalsContact CZ-N 3.32Å; Y589-G610 PolarHBondContact OH-N 3.46Å
590P85.4Confident69.8Low41 Ų4183 Ų8327%0.26645%0.448SS..PPolyproline II helixtrans-56.4126.8173.5-23.634.2000111.4S592 R611P590-S592 PolarHBondContact O-N 2.73Å; P590-R611 HydrophobicContact CG-CG 4.01Å
591T72.6Confident67.2Low115 Ų11581.1 Ų81.171%0.70645%0.451SS*.PPolyproline II helixtrans-69.4126.8177.1290000111Y589 K593Y589-T591 PolarHBondContact O-N 2.9Å; T591-K593 PolarHBondContact O-N 2.93Å
592S56.8Low64.8Low74 Ų7485 Ų8552%0.51746%0.46SS..PPolyproline II helixtrans-72.1123.9172.31790000109.9P590 N594 H595P590-S592 PolarHBondContact O-N 2.73Å; S592-N594 PolarHBondContact O-N 3.32Å; S592-H595 PolarHBondContact O-N 2.8Å
593K52.3Low62.8Low169 Ų16991.2 Ų91.274%0.73548%0.484SS*.THydrogen-bonded Turntrans-55.9-8179.4-68.5-173.9179-178.80115.3E524 T591E524-K593 WeakPolarHBondContact OE1-CE 3.46Å; E524-K593 IonicContact OE1-NZ 2.83Å; T591-K593 PolarHBondContact O-N 2.93Å
594N42.3Very low60.4Low145 Ų14594.1 Ų94.178%0.77551%0.514SS*.THydrogen-bonded Turntrans-101.56.2-176.9-70.5-17.3000115S592S592-N594 PolarHBondContact O-N 3.32Å
595H40.6Very low58.7Low117 Ų11796.8 Ų96.854%0.54254%0.538SS..  trans-117.8117.1176.7-76.1-64.5000112.4S592S592-H595 PolarHBondContact O-N 2.8Å
596S30.2Very low57.6Low78 Ų7898.3 Ų98.355%0.54554%0.541SS..  trans-60145.516652.30000110.7S598S596-S598 PolarHBondContact O-N 3.08Å
597S35.6Very low56.6Low137 Ų137106.3 Ų106.396%0.95858%0.577SS**THydrogen-bonded Turntrans-58.412.4-176.752.90000117.1
598S35.2Very low55.9Low98 Ų98108 Ų10869%0.68560%0.595SS**THydrogen-bonded Turntrans-1229-172.5560000114.7S596S596-S598 PolarHBondContact O-N 3.08Å
599Q36.7Very low55.8Low134 Ų134108 Ų10863%0.62659%0.594SS**  trans-121.3114.9171.7-67.7-165.4-16.500110.6G601Q599-G601 PolarHBondContact O-N 3Å
600K42.7Very low56Low227 Ų227107.2 Ų107.299%0.98759%0.592SS**  trans-52.181.1154.3-101.2178.9171.4176.30107.7
601G37.3Very low56.4Low47 Ų47107.1 Ų107.149%0.48559%0.586SS.*  trans-83.8128-171.400000110Q599 K603Q599-G601 PolarHBondContact O-N 3Å; G601-K603 PolarHBondContact O-N 2.94Å
602R43.4Very low57.7Low221 Ų221101.7 Ų101.783%0.83455%0.553SS**  trans-29114.6-179.7-71.7171.8171.6176.9-3.6114A604 S605R602-A604 PolarHBondContact O-N 3.31Å; R602-S605 PolarHBondContact O-N 2.94Å
603K51.7Low59.6Low141 Ų14198.3 Ų98.361%0.61353%0.529SS*.G310 helixtrans-52.7-9170.1-64.2-174.2175.3-1710114.6G601G601-K603 PolarHBondContact O-N 2.94Å
604A45.4Very low61.8Low90 Ų9090.4 Ų90.474%0.74450%0.495SS*.G310 helixtrans-77.2-16.5-175.600000115.4R602R602-A604 PolarHBondContact O-N 3.31Å
605S56.2Low64.5Low96 Ų9683.6 Ų83.667%0.67146%0.458SS*.G310 helixtrans-103.54.5-17868.80000115.2R602 K607R602-S605 PolarHBondContact O-N 2.94Å; S605-K607 PolarHBondContact O-N 3.15Å
606L68.3Low67.3Low52 Ų5278 Ų7827%0.27243%0.432SS..  trans-73.7117.2176.3-62.1177.4000109.3K584 Y589K584-L606 HydrophobicContact CB-CD1 4.35Å; K584-L606 HydrophobicContact CD-CB 4.48Å; K584-L606 WeakPolarHBondContact CE-O 3.07Å; K584-L606 HydrophobicContact CG-CB 4.29Å; K584-L606 HydrophobicContact CG-CD1 4.42Å; Y589-L606 HydrophobicContact CD1-CB 3.81Å; Y589-L606 HydrophobicContact CD1-CD1 4.48Å; Y589-L606 HydrophobicContact CD1-CD2 4.33Å; Y589-L606 HydrophobicContact CD1-CG 4.42Å; Y589-L606 HydrophobicContact CD2-CD1 4.01Å; Y589-L606 HydrophobicContact CE1-CB 3.97Å; Y589-L606 HydrophobicContact CE2-CD1 4.48Å; Y589-L606 HydrophobicContact CG-CB 4.18Å; Y589-L606 HydrophobicContact CG-CD1 4.02Å; Y589-L606 HydrophobicContact CG-CD2 4.11Å; Y589-L606 HydrophobicContact CG-CG 4.32Å
607K73.6Confident70.5Confident191 Ų19174.3 Ų74.383%0.8341%0.406SS*.  trans-98.3143.6175.4-69.1-174.7178.1-176.60109.8S605S605-K607 PolarHBondContact O-N 3.15Å
608G82.5Confident73.5Confident41 Ų4169 Ų6942%0.42337%0.366SS..SBendtrans91.6-171.2178.600000113.9Y589Y589-G608 VanDerWaalsContact CE1-O 3.23Å; Y589-G608 WeakPolarHBondContact CE1-O 3.42Å; Y589-G608 PolarHBondContact OH-O 2.89Å
609N91.9Very high76.4Confident34 Ų3464.7 Ų64.718%0.18234%0.335CS..SBendtrans-109.821.8-174.3-67.7-38.2000113.4P550 A552 I553 G554 R583 L587P550-N609 PolarHBondContact O-ND2 3.48Å; A552-N609 WeakPolarHBondContact O-CB 3.41Å; A552-N609 PolarHBondContact O-ND2 2.95Å; I553-N609 HydrophobicContact CB-CB 4.36Å; I553-N609 HydrophobicContact CG2-CB 4.2Å; G554-N609 PolarHBondContact N-O 3.35Å; R583-N609 PolarHBondContact NE-OD1 2.97Å; R583-N609 VanDerWaalsContact NE-OD1 3.12Å; R583-N609 PolarHBondContact NH2-OD1 3Å; L587-N609 WeakPolarHBondContact CD1-O 3.32Å
610G94.3Very high79Confident3 Ų362.6 Ų62.63%0.03133%0.325CS..  trans99.1175.5-177.300000113.4V588 Y589V588-G610 CarbonylContact O-C 3.5Å; V588-G610 WeakPolarHBondContact O-CA 3.36Å; Y589-G610 VanDerWaalsContact CZ-N 3.32Å; Y589-G610 PolarHBondContact OH-N 3.46Å
611R95.8Very high81.1Confident39 Ų3956.8 Ų56.815%0.14730%0.301CS..  trans-83.8112.9177.9-64.2-172.977-145.6-1.9110.5D519 D525 G554 T555 L556 V588 P590 I613D519-R611 HydrophobicContact CB-CB 4.03Å; D519-R611 HydrophobicContact CB-CG 4.3Å; D519-R611 WeakPolarHBondContact OD2-CG 3.38Å; D519-R611 IonicContact OD2-CZ 3.85Å; D519-R611 IonicContact OD2-NE 3.36Å; D519-R611 PolarHBondContact OD2-NE 3.38Å; D519-R611 IonicContact OD2-NH2 3.27Å; D519-R611 PolarHBondContact OD2-NH2 3.02Å; D525-R611 IonicContact OD2-NH2 2.79Å; D525-R611 PolarHBondContact OD2-NH2 3.26Å; G554-R611 CarbonylContact C-O 3.49Å; G554-R611 WeakPolarHBondContact CA-O 3.4Å; T555-R611 PolarHBondContact N-O 3.36Å; L556-R611 PolarHBondContact N-O 3.28Å; V588-R611 WeakPolarHBondContact O-CG 3.35Å; V588-R611 PolarHBondContact O-N 3.39Å; P590-R611 HydrophobicContact CG-CG 4.01Å; R611-I613 HydrophobicContact CB-CG2 4.3Å
612R97.8Very high83.1Confident2 Ų256.9 Ų56.91%0.00830%0.302CS..  trans-95.6104174.1-175.9176.863.686.6-4.3108.8D519 D539 D548 T555 Y615D519-R612 WeakPolarHBondContact CA-O 3.34Å; D539-R612 IonicContact OD1-NH1 2.72Å; D539-R612 PolarHBondContact OD1-NH1 3.04Å; D539-R612 IonicContact OD1-NH2 3.78Å; D539-R612 IonicContact OD2-CZ 3.96Å; D539-R612 VanDerWaalsContact OD2-CZ 3.27Å; D539-R612 IonicContact OD2-NH1 3.68Å; D539-R612 PolarHBondContact OD2-NH1 3.35Å; D539-R612 IonicContact OD2-NH2 3.74Å; D539-R612 PolarHBondContact OD2-NH2 2.9Å; D548-R612 IonicContact OD1-CZ 2.86Å; D548-R612 IonicContact OD1-NE 2.62Å; D548-R612 IonicContact OD1-NH2 3.42Å; D548-R612 PolarHBondContact OD1-NH2 2.79Å; D548-R612 IonicContact OD2-CZ 2.75Å; D548-R612 IonicContact OD2-NE 3.45Å; D548-R612 PolarHBondContact OD2-NE 2.95Å; D548-R612 IonicContact OD2-NH2 2.72Å; T555-R612 HydrophobicContact CG2-CG 3.98Å; R612-Y615 VanDerWaalsContact NH1-CD1 3.34Å; R612-Y615 PolarHBondContact O-OH 2.71Å
613I98Very high85.1Confident3 Ų347.2 Ų47.22%0.01527%0.267CS..  trans-115-12.4-174.664.7173.6000113L516 D519 T555 L556 R611 Y615L516-I613 PolarHBondContact N-O 3.26Å; D519-I613 HydrophobicContact CB-CG2 4.19Å; T555-I613 PolarHBondContact OG1-N 3.06Å; L556-I613 HydrophobicContact CB-CD1 4.05Å; L556-I613 HydrophobicContact CB-CG1 4.34Å; L556-I613 HydrophobicContact CD1-CD1 4.31Å; L556-I613 HydrophobicContact CD2-CD1 4.07Å; L556-I613 HydrophobicContact CG-CD1 4.38Å; R611-I613 HydrophobicContact CB-CG2 4.3Å; I613-Y615 VanDerWaalsContact O-CD2 3.24Å; I613-Y615 WeakPolarHBondContact O-CD2 3.45Å; I613-Y615 WeakPolarHBondContact O-CE2 3.46Å
614D98.7Very high86.5Confident2 Ų243.8 Ų43.81%0.01125%0.251CS..EExtended strand (participates in β ladder)trans-95.4122.5173.1-55.8-89000109.1G514 T555 H646 V649G514-D614 WeakPolarHBondContact O-CA 3.32Å; T555-D614 WeakPolarHBondContact CB-OD2 3.44Å; T555-D614 HydrophobicContact CG2-CB 4.17Å; T555-D614 PolarHBondContact OG1-N 3.43Å; T555-D614 VanDerWaalsContact OG1-N 3.14Å; T555-D614 PolarHBondContact OG1-OD2 2.64Å; D614-H646 IonicContact OD1-CE1 3.62Å; D614-H646 IonicContact OD1-ND1 3.31Å; D614-H646 PolarHBondContact OD1-ND1 2.82Å; D614-H646 IonicContact OD2-CE1 3.14Å; D614-H646 IonicContact OD2-CG 3.93Å; D614-H646 IonicContact OD2-ND1 3.47Å; D614-H646 PolarHBondContact OD2-ND1 3.44Å; D614-V649 HydrophobicContact CB-CG2 4.19Å
615Y98.8Very high87.9Confident2 Ų247.9 Ų47.91%0.00826%0.259CS..EExtended strand (participates in β ladder)trans-115.5151.9-173.3-69.1-103.5000112C513 G514 L516 F518 F534 D539 R612 I613 L617C513-Y615 WeakPolarHBondContact CA-O 3.18Å; C513-Y615 VanDerWaalsContact CB-O 3.23Å; C513-Y615 WeakPolarHBondContact CB-O 3.41Å; G514-Y615 PolarHBondContact N-O 2.88Å; G514-Y615 VanDerWaalsContact N-O 3.08Å; G514-Y615 PolarHBondContact O-N 2.84Å; L516-Y615 HydrophobicContact CB-CD2 3.72Å; L516-Y615 HydrophobicContact CB-CE2 3.89Å; L516-Y615 HydrophobicContact CD1-CD1 4.33Å; L516-Y615 HydrophobicContact CD1-CD2 3.44Å; L516-Y615 VanDerWaalsContact CD1-CD2 3.44Å; L516-Y615 HydrophobicContact CD1-CE2 3.98Å; L516-Y615 HydrophobicContact CD1-CG 3.63Å; L516-Y615 HydrophobicContact CG-CD2 3.49Å; L516-Y615 VanDerWaalsContact CG-CD2 3.49Å; L516-Y615 HydrophobicContact CG-CE2 4.14Å; L516-Y615 HydrophobicContact CG-CG 4.06Å; F518-Y615 HydrophobicContact CE2-CE2 4.36Å; F518-Y615 AromaticContact CE2-CZ 3.94Å; F518-Y615 WeakPolarHBondContact CE2-OH 3.41Å; F518-Y615 VanDerWaalsContact O-CE2 3.27Å; F518-Y615 WeakPolarHBondContact O-CE2 3.47Å; F518-Y615 PolarHBondContact O-OH 2.73Å; F534-Y615 HydrophobicContact CE1-CD1 4.15Å; F534-Y615 HydrophobicContact CE1-CE1 4.12Å; F534-Y615 HydrophobicContact CZ-CD1 4.37Å; F534-Y615 HydrophobicContact CZ-CE1 4.05Å; D539-Y615 WeakPolarHBondContact OD2-CD1 3.25Å; D539-Y615 WeakPolarHBondContact OD2-CE1 3.46Å; R612-Y615 VanDerWaalsContact NH1-CD1 3.34Å; R612-Y615 PolarHBondContact O-OH 2.71Å; I613-Y615 VanDerWaalsContact O-CD2 3.24Å; I613-Y615 WeakPolarHBondContact O-CD2 3.45Å; I613-Y615 WeakPolarHBondContact O-CE2 3.46Å; Y615-L617 HydrophobicContact CD1-CD2 4.14Å
616M98.6Very high88.9Confident0 Ų049.6 Ų49.60%026%0.257CS..EExtended strand (participates in β ladder)trans-139.7105.9172.2-175.569.16800107.5F126 V511 C513 P540 F634 V649 M651F126-M616 HydrophobicContact CB-CE 4.08Å; F126-M616 HydrophobicContact CB-SD 3.79Å; V511-M616 HydrophobicContact CG1-SD 3.83Å; C513-M616 HydrophobicContact CB-CE 3.74Å; C513-M616 HydrophobicContact CB-SD 3.53Å; C513-M616 VanDerWaalsContact CB-SD 3.53Å; P540-M616 VanDerWaalsContact CD-O 3.27Å; P540-M616 WeakPolarHBondContact CD-O 3.39Å; M616-F634 HydrophobicContact CB-CE2 4.07Å; M616-F634 HydrophobicContact CB-CZ 4.38Å; M616-V649 HydrophobicContact CB-CG1 4.12Å; M616-M651 HydrophobicContact CG-CB 3.48Å; M616-M651 VanDerWaalsContact CG-CB 3.48Å; M616-M651 HydrophobicContact CG-CE 3.7Å; M616-M651 HydrophobicContact CG-CG 4.38Å; M616-M651 HydrophobicContact CG-SD 4.06Å; M616-M651 HydrophobicContact SD-CB 4.5Å; M616-M651 HydrophobicContact SD-CE 4.26Å
617L98.7Very high89.9Confident1 Ų148.3 Ų48.31%0.00525%0.248CC..EExtended strand (participates in β ladder)trans-117.3150.3-170.2-45.6178000110.2V511 I512 L533 F534 K538 D539 Y615V511-L617 VanDerWaalsContact CA-O 3.3Å; V511-L617 WeakPolarHBondContact CA-O 3.05Å; V511-L617 WeakPolarHBondContact CG1-O 3.43Å; I512-L617 HydrophobicContact CB-CB 4.3Å; I512-L617 HydrophobicContact CB-CD1 4.43Å; I512-L617 PolarHBondContact N-O 2.95Å; I512-L617 PolarHBondContact O-N 3.33Å; L533-L617 HydrophobicContact CD2-CD1 4.13Å; F534-L617 HydrophobicContact CD1-CD2 4.49Å; F534-L617 HydrophobicContact CE1-CD1 4.19Å; F534-L617 HydrophobicContact CE1-CD2 4.08Å; K538-L617 WeakPolarHBondContact O-CA 3.4Å; D539-L617 HydrophobicContact CB-CD2 3.52Å; Y615-L617 HydrophobicContact CD1-CD2 4.14Å
618Y98.1Very high90.7Very high26 Ų2645 Ų4510%0.10223%0.234CC..EExtended strand (participates in β ladder)trans-137.2157.2174.472.9-74000110.6D510 Y537 K538 P540 E620 V629 V631 M651 L653D510-Y618 WeakPolarHBondContact O-CA 3.33Å; Y537-Y618 CarbonylContact C-O 3.49Å; Y537-Y618 WeakPolarHBondContact CA-O 3.3Å; K538-Y618 HydrophobicContact CB-CD1 4.25Å; K538-Y618 HydrophobicContact CB-CE1 3.79Å; K538-Y618 HydrophobicContact CD-CE2 4.39Å; K538-Y618 PolarHBondContact N-O 3.25Å; K538-Y618 PolarHBondContact O-N 3.4Å; K538-Y618 VanDerWaalsContact O-N 3.12Å; P540-Y618 HydrophobicContact CG-CD1 4.2Å; P540-Y618 HydrophobicContact CG-CE1 4.02Å; Y618-E620 HydrophobicContact CE2-CG 4.02Å; Y618-V629 HydrophobicContact CD2-CG1 4.41Å; Y618-V631 HydrophobicContact CD1-CG2 4.11Å; Y618-V631 HydrophobicContact CE1-CG2 3.53Å; Y618-M651 HydrophobicContact CD1-CE 4.47Å; Y618-M651 HydrophobicContact CD1-SD 4.02Å; Y618-L653 HydrophobicContact CD1-CD2 4.49Å; Y618-L653 HydrophobicContact CD2-CD2 4.31Å; Y618-L653 HydrophobicContact CG-CD2 4.13Å
619T95.8Very high91.2Very high6 Ų643.3 Ų43.34%0.03722%0.215CC..  trans-118.2150.4169.8-171.60000111.4D510 H536 Y537 E621D510-T619 HydrophobicContact CB-CG2 3.63Å; D510-T619 PolarHBondContact O-N 2.92Å; D510-T619 VanDerWaalsContact O-N 3.11Å; H536-T619 WeakPolarHBondContact O-CB 3.25Å; H536-T619 PolarHBondContact O-OG1 3.33Å; Y537-T619 HydrophobicContact CD1-CG2 4.13Å; Y537-T619 HydrophobicContact CE1-CG2 3.69Å; T619-E621 WeakPolarHBondContact OG1-CB 3.14Å; T619-E621 PolarHBondContact OG1-N 2.87Å
620E90.8Very high91.3Very high91 Ų9145.8 Ų45.843%0.42523%0.226SC..  trans-97.7-7.3167.2-68.9164.7-156.400110.7K538 Y618K538-E620 IonicContact NZ-OE1 3.94Å; K538-E620 PolarHBondContact NZ-OE1 2.9Å; K538-E620 IonicContact NZ-OE2 3.81Å; K538-E620 PolarHBondContact NZ-OE2 3.45Å; Y618-E620 HydrophobicContact CE2-CG 4.02Å
621E87.8Confident91.4Very high104 Ų10446.2 Ų46.249%0.48623%0.228SC..THydrogen-bonded Turntrans-80.1134.5-176.3-59.6-176.7171.200111.7H536 T619 L623H536-E621 IonicContact CG-OE2 3.94Å; H536-E621 IonicContact ND1-OE1 3.99Å; H536-E621 IonicContact ND1-OE2 3.07Å; H536-E621 PolarHBondContact ND1-OE2 3.16Å; T619-E621 WeakPolarHBondContact OG1-CB 3.14Å; T619-E621 PolarHBondContact OG1-N 2.87Å; E621-L623 PolarHBondContact O-N 2.93Å
622G79.5Confident91.4Very high49 Ų4946.7 Ų46.751%0.50523%0.232SC..THydrogen-bonded Turntrans68.913.6176.700000114.5R492R492-G622 VanDerWaalsContact NH2-C 3.33Å; R492-G622 PolarHBondContact NH2-O 2.99Å
623L85.1Confident91.3Very high19 Ų1948.5 Ų48.510%0.09924%0.24CC..SBendtrans-71.1168.7168.1-56.1-174.9000110.5V507 E621 L625 V629V507-L623 HydrophobicContact CG1-CD2 3.91Å; E621-L623 PolarHBondContact O-N 2.93Å; L623-L625 PolarHBondContact O-N 2.94Å; L623-V629 HydrophobicContact CD1-CB 3.83Å; L623-V629 HydrophobicContact CD1-CG2 3.29Å
624Y80.3Confident91.3Very high69 Ų6948.5 Ų48.527%0.27124%0.24SC..  trans-58.5126.5172.6-176.2-110.5000109.9L506 V507 E626 W627L506-Y624 HydrophobicContact CB-CD2 4.41Å; L506-Y624 HydrophobicContact CB-CG 4.34Å; L506-Y624 HydrophobicContact CD1-CD1 4.38Å; L506-Y624 HydrophobicContact CD1-CD2 4.32Å; L506-Y624 HydrophobicContact CD1-CE1 4.38Å; L506-Y624 HydrophobicContact CD1-CE2 4.3Å; L506-Y624 HydrophobicContact CD1-CG 4.34Å; L506-Y624 HydrophobicContact CD2-CD2 3.52Å; L506-Y624 HydrophobicContact CD2-CE2 3.59Å; L506-Y624 HydrophobicContact CD2-CG 4.23Å; L506-Y624 HydrophobicContact CG-CD2 4.29Å; V507-Y624 PolarHBondContact O-N 2.89Å; V507-Y624 VanDerWaalsContact O-N 3.12Å; Y624-E626 HydrophobicContact CD1-CB 4.15Å; Y624-E626 HydrophobicContact CE1-CB 3.78Å; Y624-E626 HydrophobicContact CE1-CG 4.06Å; Y624-E626 VanDerWaalsContact CE1-OE2 3.31Å; Y624-E626 WeakPolarHBondContact CE1-OE2 3.42Å; Y624-E626 PolarHBondContact O-N 3.38Å; Y624-E626 PolarHBondContact OH-OE2 3.41Å; Y624-W627 AromaticContact CD1-CD1 3.64Å; Y624-W627 AromaticContact CD1-CD2 3.94Å; Y624-W627 HydrophobicContact CD1-CD2 3.94Å; Y624-W627 AromaticContact CD1-CE2 3.8Å; Y624-W627 AromaticContact CD1-CG 3.85Å; Y624-W627 HydrophobicContact CD1-CG 3.85Å; Y624-W627 HydrophobicContact CD1-CZ2 4.48Å; Y624-W627 AromaticContact CD1-NE1 3.59Å; Y624-W627 AromaticContact CE1-NE1 3.95Å; Y624-W627 PolarHBondContact O-N 3.45Å
625L74.4Confident91.3Very high175 Ų17548.5 Ų48.592%0.91624%0.241SC*.THydrogen-bonded Turntrans-57.7-25.9-162.8-76.8163.5000114.9L623L623-L625 PolarHBondContact O-N 2.94Å
626E79.2Confident91.3Very high132 Ų13248.6 Ų48.662%0.61724%0.241SC*.THydrogen-bonded Turntrans-92.8-8.7-177.7-59.4177.4151.100112.7Y624Y624-E626 HydrophobicContact CD1-CB 4.15Å; Y624-E626 HydrophobicContact CE1-CB 3.78Å; Y624-E626 HydrophobicContact CE1-CG 4.06Å; Y624-E626 VanDerWaalsContact CE1-OE2 3.31Å; Y624-E626 WeakPolarHBondContact CE1-OE2 3.42Å; Y624-E626 PolarHBondContact O-N 3.38Å; Y624-E626 PolarHBondContact OH-OE2 3.41Å
627W87.6Confident91.3Very high26 Ų2648.6 Ų48.610%0.09824%0.241CC..  trans-97.6135.7-176.7-66.3-0.6000111.8W115 A117 I458 L506 A508 Y624 V655 S656 T657W115-W627 HydrophobicContact CH2-CE3 4.25Å; W115-W627 AromaticContact CH2-CH2 3.97Å; W115-W627 HydrophobicContact CH2-CH2 3.97Å; W115-W627 AromaticContact CH2-CZ3 3.82Å; W115-W627 HydrophobicContact CH2-CZ3 3.82Å; W115-W627 HydrophobicContact CZ3-CH2 4.3Å; W115-W627 HydrophobicContact CZ3-CZ3 4.14Å; A117-W627 HydrophobicContact CB-CZ2 4.09Å; I458-W627 HydrophobicContact CB-CH2 4.3Å; I458-W627 HydrophobicContact CD1-CH2 3.77Å; I458-W627 HydrophobicContact CD1-CZ2 4.42Å; I458-W627 HydrophobicContact CG1-CH2 3.84Å; I458-W627 HydrophobicContact CG2-CH2 3.51Å; I458-W627 HydrophobicContact CG2-CZ3 3.53Å; L506-W627 HydrophobicContact CB-CH2 3.96Å; L506-W627 HydrophobicContact CB-CZ3 4.27Å; L506-W627 HydrophobicContact CD1-CH2 4.1Å; L506-W627 HydrophobicContact CD1-CZ2 3.91Å; A508-W627 HydrophobicContact CB-CE3 4.31Å; A508-W627 HydrophobicContact CB-CZ3 3.88Å; Y624-W627 AromaticContact CD1-CD1 3.64Å; Y624-W627 AromaticContact CD1-CD2 3.94Å; Y624-W627 HydrophobicContact CD1-CD2 3.94Å; Y624-W627 AromaticContact CD1-CE2 3.8Å; Y624-W627 AromaticContact CD1-CG 3.85Å; Y624-W627 HydrophobicContact CD1-CG 3.85Å; Y624-W627 HydrophobicContact CD1-CZ2 4.48Å; Y624-W627 AromaticContact CD1-NE1 3.59Å; Y624-W627 AromaticContact CE1-NE1 3.95Å; Y624-W627 PolarHBondContact O-N 3.45Å; W627-V655 HydrophobicContact CB-CG1 4.15Å; W627-V655 HydrophobicContact CD2-CG1 4.14Å; W627-V655 HydrophobicContact CE3-CG1 3.66Å; W627-V655 HydrophobicContact CG-CG1 4.38Å; W627-V655 HydrophobicContact CZ3-CG1 4.4Å; W627-S656 CarbonylContact C-O 3.33Å; W627-S656 VanDerWaalsContact CA-O 3.23Å; W627-S656 WeakPolarHBondContact CA-O 3.2Å; W627-T657 HydrophobicContact CZ2-CG2 4.44Å
628K90.4Very high91.3Very high120 Ų12048.6 Ų48.652%0.52224%0.241SC..EExtended strand (participates in β ladder)trans-100.9132174.6-163.7-171.7-167.6-169.20109.2E630 V655 S656K628-E630 HydrophobicContact CD-CG 4.03Å; K628-E630 WeakPolarHBondContact CE-OE1 3.34Å; K628-E630 HydrophobicContact CG-CG 4.09Å; K628-E630 IonicContact NZ-OE1 3.21Å; K628-E630 PolarHBondContact NZ-OE1 3.05Å; K628-V655 WeakPolarHBondContact O-CA 3.4Å; K628-S656 PolarHBondContact N-O 3.14Å; K628-S656 PolarHBondContact O-N 3.12Å
629V92.9Very high91.3Very high6 Ų647.9 Ų47.94%0.03624%0.239CC..EExtended strand (participates in β ladder)trans-111.9123.4174.11790000109.5A508 Y618 L623 L653 M654 V655A508-V629 VanDerWaalsContact O-CG2 3.29Å; A508-V629 WeakPolarHBondContact O-CG2 3.33Å; Y618-V629 HydrophobicContact CD2-CG1 4.41Å; L623-V629 HydrophobicContact CD1-CB 3.83Å; L623-V629 HydrophobicContact CD1-CG2 3.29Å; V629-L653 HydrophobicContact CG1-CB 4.14Å; V629-L653 HydrophobicContact CG1-CD1 4.04Å; V629-L653 HydrophobicContact CG1-CD2 4.16Å; V629-L653 HydrophobicContact CG1-CG 4.35Å; V629-M654 WeakPolarHBondContact CA-O 3.5Å; V629-V655 HydrophobicContact CG2-CB 4.46Å; V629-V655 HydrophobicContact CG2-CG1 4.2Å; V629-V655 HydrophobicContact CG2-CG2 4.01Å
630E93.9Very high91.5Very high87 Ų8747.8 Ų47.841%0.40724%0.238SC..EExtended strand (participates in β ladder)trans-131.5145.1179.7-61.1-173.2135.500110K628 E632 L653 M654K628-E630 HydrophobicContact CD-CG 4.03Å; K628-E630 WeakPolarHBondContact CE-OE1 3.34Å; K628-E630 HydrophobicContact CG-CG 4.09Å; K628-E630 IonicContact NZ-OE1 3.21Å; K628-E630 PolarHBondContact NZ-OE1 3.05Å; E630-E632 PolarHBondContact O-N 3.18Å; E630-L653 CarbonylContact O-C 3.47Å; E630-L653 WeakPolarHBondContact O-CA 3.42Å; E630-M654 PolarHBondContact N-O 3.06Å; E630-M654 PolarHBondContact O-N 2.72Å
631V96.6Very high91.8Very high11 Ų1143.6 Ų43.67%0.06722%0.219CC..EExtended strand (participates in β ladder)trans-69.9125.1169.1-176.20000107.9F350 P540 Y618 M651 L653F350-V631 HydrophobicContact CB-CB 4.32Å; F350-V631 HydrophobicContact CB-CG1 4.19Å; F350-V631 WeakPolarHBondContact CB-O 3.11Å; F350-V631 HydrophobicContact CD1-CB 3.94Å; F350-V631 HydrophobicContact CD1-CG1 4.1Å; F350-V631 HydrophobicContact CD2-CB 4.43Å; F350-V631 HydrophobicContact CD2-CG1 3.7Å; F350-V631 HydrophobicContact CE1-CB 4.34Å; F350-V631 HydrophobicContact CE1-CG1 4.39Å; F350-V631 HydrophobicContact CE2-CG1 4.03Å; F350-V631 HydrophobicContact CG-CB 4Å; F350-V631 HydrophobicContact CG-CG1 3.74Å; F350-V631 HydrophobicContact CZ-CG1 4.36Å; P540-V631 HydrophobicContact CG-CG2 4.12Å; Y618-V631 HydrophobicContact CD1-CG2 4.11Å; Y618-V631 HydrophobicContact CE1-CG2 3.53Å; V631-M651 HydrophobicContact CG1-CG 4.2Å; V631-M651 HydrophobicContact CG2-SD 4.24Å; V631-L653 HydrophobicContact CB-CD2 4.49Å; V631-L653 HydrophobicContact CG2-CD2 3.87Å
632E95.3Very high92.1Very high50 Ų5039.4 Ų39.423%0.23420%0.203CC..EExtended strand (participates in β ladder)trans-91.7-39.5172.3-176.1-177.9-179.400110.2S123 K168 D351 E630 R652S123-E632 WeakPolarHBondContact CB-OE2 3.18Å; S123-E632 PolarHBondContact OG-OE2 2.66Å; K168-E632 IonicContact NZ-OE1 2.92Å; K168-E632 PolarHBondContact NZ-OE1 2.93Å; D351-E632 PolarHBondContact N-O 3.22Å; E630-E632 PolarHBondContact O-N 3.18Å; E632-R652 HydrophobicContact CB-CB 4.32Å; E632-R652 HydrophobicContact CB-CG 4.18Å; E632-R652 PolarHBondContact N-O 3.35Å; E632-R652 WeakPolarHBondContact OE2-CD 3.4Å
633E96.9Very high92.9Very high40 Ų4037.4 Ų37.419%0.18718%0.181CC..EExtended strand (participates in β ladder)trans-150.8141.4-171.5-169.5-173.1167.600110.9D351 M651 R652D351-E633 CarbonylContact O-C 3.57Å; D351-E633 VanDerWaalsContact O-CA 3.23Å; D351-E633 WeakPolarHBondContact O-CA 3.46Å; E633-M651 CarbonylContact O-C 3.6Å; E633-M651 WeakPolarHBondContact O-CA 3.44Å; E633-R652 HydrophobicContact CB-CB 3.82Å; E633-R652 PolarHBondContact O-N 3.48Å; E633-R652 IonicContact OE2-CZ 3.48Å; E633-R652 IonicContact OE2-NE 3.89Å; E633-R652 PolarHBondContact OE2-NE 3.16Å; E633-R652 VanDerWaalsContact OE2-NE 3.14Å; E633-R652 IonicContact OE2-NH2 3.29Å
634F98.6Very high93.5Very high2 Ų236.5 Ų36.51%0.00918%0.176CC..EExtended strand (participates in β ladder)trans-133.2131.9169.1-163.7-79.5000110.6F350 D351 H352 E353 P540 C541 W551 M616 F636 V649 A650 M651F350-F634 HydrophobicContact CD2-CB 4.29Å; F350-F634 HydrophobicContact CE2-CB 3.82Å; D351-F634 PolarHBondContact O-N 3.07Å; H352-F634 VanDerWaalsContact CA-O 3.22Å; H352-F634 WeakPolarHBondContact CA-O 3.38Å; E353-F634 PolarHBondContact N-O 3.12Å; P540-F634 HydrophobicContact CB-CD2 3.74Å; P540-F634 HydrophobicContact CB-CE2 4.01Å; P540-F634 HydrophobicContact CB-CG 4.48Å; P540-F634 HydrophobicContact CG-CD2 3.79Å; P540-F634 HydrophobicContact CG-CE2 3.84Å; C541-F634 WeakPolarHBondContact SG-CE1 3.3Å; C541-F634 WeakPolarHBondContact SG-CZ 3.43Å; W551-F634 HydrophobicContact CH2-CB 4.26Å; W551-F634 AromaticContact CH2-CD1 3.93Å; W551-F634 HydrophobicContact CH2-CD1 3.93Å; W551-F634 HydrophobicContact CH2-CG 4.12Å; W551-F634 AromaticContact CZ3-CD1 3.8Å; W551-F634 HydrophobicContact CZ3-CD1 3.8Å; W551-F634 HydrophobicContact CZ3-CE1 4.34Å; W551-F634 HydrophobicContact CZ3-CG 4.4Å; M616-F634 HydrophobicContact CB-CE2 4.07Å; M616-F634 HydrophobicContact CB-CZ 4.38Å; F634-F636 HydrophobicContact CD1-CE2 4.44Å; F634-F636 HydrophobicContact CE1-CE1 4.26Å; F634-F636 HydrophobicContact CE1-CE2 4.24Å; F634-F636 AromaticContact CE1-CZ 3.98Å; F634-F636 HydrophobicContact CE1-CZ 3.98Å; F634-V649 HydrophobicContact CD1-CG1 4.47Å; F634-V649 HydrophobicContact CE1-CG1 3.45Å; F634-V649 VanDerWaalsContact CE1-CG1 3.45Å; F634-V649 HydrophobicContact CE2-CG1 4.09Å; F634-V649 HydrophobicContact CZ-CG1 3.22Å; F634-A650 CarbonylContact C-O 3.49Å; F634-A650 WeakPolarHBondContact CA-O 3.33Å; F634-M651 HydrophobicContact CD2-CB 4.06Å; F634-M651 HydrophobicContact CD2-CG 4.24Å; F634-M651 HydrophobicContact CE2-CB 4.38Å
635S98.3Very high94.2Very high3 Ų333.6 Ų33.62%0.02117%0.165CC..EExtended strand (participates in β ladder)trans-137.5141.9-177.854.10000114.5E353 V649 A650E353-S635 VanDerWaalsContact O-CA 3.25Å; E353-S635 WeakPolarHBondContact O-CA 3.23Å; S635-V649 WeakPolarHBondContact O-CA 3.22Å; S635-A650 PolarHBondContact N-O 3.28Å; S635-A650 PolarHBondContact O-N 3.27Å
636F98.8Very high95.4Very high3 Ų325.7 Ų25.71%0.01312%0.124CC..EExtended strand (participates in β ladder)trans-96.6125164.6-59.7-84.9000108.5E353 I354 S355 W551 A552 I553 T555 F634 V649E353-F636 PolarHBondContact O-N 3.24Å; I354-F636 CarbonylContact C-O 3.54Å; I354-F636 VanDerWaalsContact CA-O 3.3Å; I354-F636 WeakPolarHBondContact CA-O 3.27Å; S355-F636 PolarHBondContact N-O 3.47Å; W551-F636 AromaticContact CE3-CE2 3.99Å; W551-F636 HydrophobicContact CE3-CE2 3.99Å; W551-F636 AromaticContact CZ3-CE2 3.75Å; W551-F636 HydrophobicContact CZ3-CE2 3.75Å; W551-F636 HydrophobicContact CZ3-CZ 4.3Å; A552-F636 HydrophobicContact CB-CZ 4.29Å; I553-F636 HydrophobicContact CD1-CB 3.99Å; I553-F636 HydrophobicContact CD1-CD1 4.41Å; I553-F636 HydrophobicContact CD1-CD2 4.28Å; I553-F636 HydrophobicContact CD1-CG 3.99Å; I553-F636 HydrophobicContact CG1-CB 4.17Å; I553-F636 HydrophobicContact CG1-CD1 3.75Å; I553-F636 HydrophobicContact CG1-CD2 3.69Å; I553-F636 HydrophobicContact CG1-CE1 3.99Å; I553-F636 HydrophobicContact CG1-CE2 3.92Å; I553-F636 HydrophobicContact CG1-CG 3.59Å; I553-F636 HydrophobicContact CG1-CZ 4.07Å; I553-F636 WeakPolarHBondContact O-CE1 3.28Å; T555-F636 HydrophobicContact CG2-CD1 3.92Å; T555-F636 HydrophobicContact CG2-CE1 3.91Å; F634-F636 HydrophobicContact CD1-CE2 4.44Å; F634-F636 HydrophobicContact CE1-CE1 4.26Å; F634-F636 HydrophobicContact CE1-CE2 4.24Å; F634-F636 AromaticContact CE1-CZ 3.98Å; F634-F636 HydrophobicContact CE1-CZ 3.98Å; F636-V649 HydrophobicContact CD1-CG2 4.13Å; F636-V649 HydrophobicContact CE1-CG2 4.41Å
637I98.8Very high96.3Very high0 Ų019.5 Ų19.50%010%0.095CC..EExtended strand (participates in β ladder)trans-106.2131.4-165.9-61.3157000110.2S355 F358 Q639 P648 A650S355-I637 CarbonylContact O-C 3.55Å; S355-I637 VanDerWaalsContact O-CA 3.3Å; S355-I637 WeakPolarHBondContact O-CA 3.46Å; F358-I637 HydrophobicContact CD1-CD1 3.65Å; F358-I637 HydrophobicContact CD2-CG2 3.91Å; F358-I637 HydrophobicContact CE1-CD1 3.88Å; F358-I637 HydrophobicContact CE2-CG2 4.03Å; F358-I637 HydrophobicContact CG-CD1 4.09Å; F358-I637 HydrophobicContact CG-CG2 4.27Å; F358-I637 HydrophobicContact CZ-CD1 4.49Å; I637-Q639 HydrophobicContact CG2-CB 3.75Å; I637-P648 HydrophobicContact CB-CB 3.96Å; I637-P648 HydrophobicContact CB-CG 4.36Å; I637-P648 HydrophobicContact CD1-CB 4.02Å; I637-P648 HydrophobicContact CG2-CB 4.44Å; I637-P648 HydrophobicContact CG2-CG 4.46Å; I637-P648 PolarHBondContact N-O 3.02Å; I637-P648 VanDerWaalsContact O-CD 3.31Å; I637-P648 WeakPolarHBondContact O-CD 3.48Å; I637-A650 HydrophobicContact CD1-CB 3.72Å
638T98.7Very high96.8Very high1 Ų118.4 Ų18.41%0.0069%0.091CC..  trans-105.45.2177.263.10000112.8I354 S355 A356 P570 L573 Q574 L577 L640 A641 L647I354-T638 HydrophobicContact CG2-CG2 3.78Å; S355-T638 PolarHBondContact O-N 2.91Å; S355-T638 PolarHBondContact O-OG1 3.08Å; A356-T638 WeakPolarHBondContact CA-OG1 3.45Å; P570-T638 WeakPolarHBondContact CA-O 3.12Å; P570-T638 PolarHBondContact O-OG1 3.25Å; L573-T638 HydrophobicContact CB-CG2 4.22Å; L573-T638 HydrophobicContact CD2-CG2 4.03Å; L573-T638 HydrophobicContact CG-CG2 3.76Å; Q574-T638 HydrophobicContact CB-CG2 4.39Å; L577-T638 HydrophobicContact CD1-CG2 3.88Å; T638-L640 PolarHBondContact O-N 2.81Å; T638-A641 VanDerWaalsContact O-CB 3.32Å; T638-A641 WeakPolarHBondContact O-CB 3.4Å; T638-A641 PolarHBondContact O-N 3.26Å; T638-L647 HydrophobicContact CG2-CD2 4.26Å
639Q98.4Very high97.2Very high12 Ų1212.7 Ų12.76%0.0567%0.066CC..THydrogen-bonded Turntrans-58.6-25.4-176.7-154.8176.54.300113.4R157 A356 F358 I637 A641R157-Q639 HydrophobicContact CB-CG 4.23Å; R157-Q639 WeakPolarHBondContact CD-O 3.33Å; R157-Q639 PolarHBondContact NH1-O 3.04Å; R157-Q639 PolarHBondContact O-NE2 3.5Å; R157-Q639 PolarHBondContact O-OE1 3.16Å; A356-Q639 WeakPolarHBondContact O-CA 3.4Å; A356-Q639 VanDerWaalsContact O-CB 3.3Å; A356-Q639 WeakPolarHBondContact O-CB 3.27Å; A356-Q639 WeakPolarHBondContact O-CG 3.4Å; F358-Q639 HydrophobicContact CD2-CB 4.12Å; F358-Q639 VanDerWaalsContact CD2-OE1 3.31Å; F358-Q639 HydrophobicContact CE2-CB 4.44Å; I637-Q639 HydrophobicContact CG2-CB 3.75Å; Q639-A641 VanDerWaalsContact C-N 3.34Å
640L98.2Very high97.5Very high4 Ų412.5 Ų12.52%0.0217%0.065CC..THydrogen-bonded Turntrans-92.717177.7-53.6-171.3000114A129 V131 I154 R157 I158 F358 T638 G642 L643 T644 P648A129-L640 HydrophobicContact CB-CD1 4.5Å; V131-L640 HydrophobicContact CG1-CD1 4.33Å; I154-L640 HydrophobicContact CB-CD2 4.49Å; I154-L640 HydrophobicContact CG1-CD2 4.37Å; I154-L640 HydrophobicContact CG2-CD1 4.13Å; I154-L640 HydrophobicContact CG2-CD2 4.21Å; R157-L640 HydrophobicContact CB-CD2 4.08Å; I158-L640 HydrophobicContact CG1-CD2 4.39Å; F358-L640 HydrophobicContact CE2-CD1 4.18Å; F358-L640 HydrophobicContact CE2-CD2 4.01Å; F358-L640 HydrophobicContact CE2-CG 3.89Å; F358-L640 HydrophobicContact CZ-CD1 4.22Å; F358-L640 HydrophobicContact CZ-CG 4.39Å; T638-L640 PolarHBondContact O-N 2.81Å; L640-G642 PolarHBondContact O-N 3.47Å; L640-L643 HydrophobicContact CD2-CD1 4.46Å; L640-L643 WeakPolarHBondContact O-CA 3.41Å; L640-L643 VanDerWaalsContact O-CB 3.32Å; L640-L643 WeakPolarHBondContact O-CB 3.3Å; L640-L643 PolarHBondContact O-N 3.5Å; L640-T644 HydrophobicContact CB-CG2 3.86Å; L640-T644 HydrophobicContact CD1-CG2 4.18Å; L640-P648 HydrophobicContact CB-CG 4.47Å; L640-P648 HydrophobicContact CD1-CG 3.64Å; L640-P648 HydrophobicContact CG-CG 3.94Å
641A97.2Very high97.7Very high3 Ų38.5 Ų8.53%0.0255%0.046CC..THydrogen-bonded Turntrans-45.8129.4173.900000112.1R157 L573 T638 Q639 L643R157-A641 PolarHBondContact NH1-O 2.86Å; R157-A641 VanDerWaalsContact NH1-O 3.08Å; L573-A641 HydrophobicContact CB-CB 4.16Å; L573-A641 HydrophobicContact CD2-CB 3.78Å; T638-A641 VanDerWaalsContact O-CB 3.32Å; T638-A641 WeakPolarHBondContact O-CB 3.4Å; T638-A641 PolarHBondContact O-N 3.26Å; Q639-A641 VanDerWaalsContact C-N 3.34Å; A641-L643 PolarHBondContact O-N 3.4Å
642G94.2Very high97.8Very high15 Ų158.4 Ų8.416%0.1555%0.045CC..THydrogen-bonded Turntrans75.6-0.9-177.800000115.6L640L640-G642 PolarHBondContact O-N 3.47Å
643L96.8Very high97.9Very high7 Ų76.1 Ų6.14%0.0373%0.034CC..THydrogen-bonded Turntrans-114-10.4-175.1-55.7176.2000114.1R150 E153 I154 R157 L640 A641R150-L643 HydrophobicContact CG-CD2 4.21Å; R150-L643 PolarHBondContact NE-O 3.18Å; R150-L643 PolarHBondContact NH2-O 2.89Å; E153-L643 HydrophobicContact CB-CD1 4.42Å; E153-L643 HydrophobicContact CG-CD1 3.62Å; E153-L643 HydrophobicContact CG-CD2 4.02Å; E153-L643 HydrophobicContact CG-CG 4.49Å; I154-L643 HydrophobicContact CD1-CB 4.23Å; I154-L643 HydrophobicContact CG1-CB 3.91Å; I154-L643 HydrophobicContact CG1-CD1 3.9Å; R157-L643 VanDerWaalsContact CZ-CD1 3.48Å; L640-L643 HydrophobicContact CD2-CD1 4.46Å; L640-L643 WeakPolarHBondContact O-CA 3.41Å; L640-L643 VanDerWaalsContact O-CB 3.32Å; L640-L643 WeakPolarHBondContact O-CB 3.3Å; L640-L643 PolarHBondContact O-N 3.5Å; A641-L643 PolarHBondContact O-N 3.4Å
644T97Very high97.8Very high0 Ų06.6 Ų6.60%04%0.037CC..  trans-161.9159.6175.6-176.60000107.5N130 L562 L640 H646N130-T644 PolarHBondContact O-OG1 3.26Å; L562-T644 WeakPolarHBondContact CD1-O 3.3Å; L640-T644 HydrophobicContact CB-CG2 3.86Å; L640-T644 HydrophobicContact CD1-CG2 4.18Å; T644-H646 VanDerWaalsContact C-N 3.33Å; T644-H646 WeakPolarHBondContact CG2-O 2.97Å
645D96.7Very high97.5Very high8 Ų86.5 Ų6.54%0.0434%0.037CC..SBendtrans-91.78.3175.160-24.8000113C132 N142 L557C132-D645 PolarHBondContact SG-OD1 3.2Å; N142-D645 PolarHBondContact ND2-OD2 2.94Å; L557-D645 VanDerWaalsContact CB-O 3.29Å; L557-D645 WeakPolarHBondContact CB-O 3.19Å; L557-D645 PolarHBondContact N-O 3.05Å
646H98.3Very high97.1Very high9 Ų97.5 Ų7.54%0.0424%0.044CC..BIsolated β-bridgetrans-114.5146.1172.3-73.5-118.9000112.9N130 D515 T555 D614 T644 P648N130-H646 HydrophobicContact CB-CB 3.91Å; D515-H646 IonicContact OD2-CE1 2.83Å; D515-H646 PolarHBondContact OD2-CE1 3.04Å; D515-H646 VanDerWaalsContact OD2-CE1 3.28Å; D515-H646 IonicContact OD2-NE2 3.65Å; T555-H646 CarbonylContact O-C 3.46Å; T555-H646 WeakPolarHBondContact O-CA 3.24Å; D614-H646 IonicContact OD1-CE1 3.62Å; D614-H646 IonicContact OD1-ND1 3.31Å; D614-H646 PolarHBondContact OD1-ND1 2.82Å; D614-H646 IonicContact OD2-CE1 3.14Å; D614-H646 IonicContact OD2-CG 3.93Å; D614-H646 IonicContact OD2-ND1 3.47Å; D614-H646 PolarHBondContact OD2-ND1 3.44Å; T644-H646 VanDerWaalsContact C-N 3.33Å; T644-H646 WeakPolarHBondContact CG2-O 2.97Å; H646-P648 WeakPolarHBondContact O-CD 3.41Å
647L98.6Very high96.2Very high3 Ų38.3 Ų8.32%0.0165%0.049CC..  trans-84.1121.4166.3-62.1-179.9000109.5I553 T555 L557 L573 L577 L587 T638I553-L647 HydrophobicContact CD1-CD1 3.91Å; T555-L647 PolarHBondContact O-N 3.18Å; L557-L647 HydrophobicContact CD1-CD2 4.11Å; L557-L647 HydrophobicContact CD2-CD2 4.14Å; L557-L647 HydrophobicContact CD2-CG 4.4Å; L557-L647 HydrophobicContact CG-CD2 4.28Å; L557-L647 HydrophobicContact CG-CG 4.37Å; L573-L647 HydrophobicContact CD2-CD2 4Å; L577-L647 HydrophobicContact CD1-CD1 3.55Å; L577-L647 HydrophobicContact CD1-CD2 4.01Å; L577-L647 HydrophobicContact CD1-CG 4.42Å; L587-L647 HydrophobicContact CD2-CD1 4.23Å; T638-L647 HydrophobicContact CG2-CD2 4.26Å
648P98.8Very high94.6Very high2 Ų211.1 Ų11.11%0.0138%0.078CC..  trans-57.6149.1166.4-20.127.3000111.8S128 A129 F358 I637 L640 H646S128-P648 CarbonylContact O-C 3.51Å; S128-P648 WeakPolarHBondContact O-CA 3.39Å; S128-P648 WeakPolarHBondContact O-CB 3.44Å; A129-P648 HydrophobicContact CB-CB 3.71Å; A129-P648 HydrophobicContact CB-CG 3.72Å; F358-P648 HydrophobicContact CE1-CB 3.81Å; F358-P648 HydrophobicContact CE1-CG 4.34Å; F358-P648 HydrophobicContact CE2-CB 4.35Å; F358-P648 HydrophobicContact CE2-CG 4.05Å; F358-P648 HydrophobicContact CZ-CB 3.49Å; F358-P648 VanDerWaalsContact CZ-CB 3.49Å; F358-P648 HydrophobicContact CZ-CG 3.51Å; I637-P648 HydrophobicContact CB-CB 3.96Å; I637-P648 HydrophobicContact CB-CG 4.36Å; I637-P648 HydrophobicContact CD1-CB 4.02Å; I637-P648 HydrophobicContact CG2-CB 4.44Å; I637-P648 HydrophobicContact CG2-CG 4.46Å; I637-P648 PolarHBondContact N-O 3.02Å; I637-P648 VanDerWaalsContact O-CD 3.31Å; I637-P648 WeakPolarHBondContact O-CD 3.48Å; L640-P648 HydrophobicContact CB-CG 4.47Å; L640-P648 HydrophobicContact CD1-CG 3.64Å; L640-P648 HydrophobicContact CG-CG 3.94Å; H646-P648 WeakPolarHBondContact O-CD 3.41Å
649V98.8Very high92.6Very high1 Ų118.8 Ų18.81%0.00611%0.114CC..EExtended strand (participates in β ladder)trans-122.8138.5178-179.40000108.7G127 S128 T555 D614 M616 F634 S635 F636G127-V649 CarbonylContact C-O 3.54Å; G127-V649 WeakPolarHBondContact CA-O 3.28Å; S128-V649 PolarHBondContact N-O 3.44Å; S128-V649 PolarHBondContact O-N 3.46Å; T555-V649 HydrophobicContact CG2-CG2 3.67Å; D614-V649 HydrophobicContact CB-CG2 4.19Å; M616-V649 HydrophobicContact CB-CG1 4.12Å; F634-V649 HydrophobicContact CD1-CG1 4.47Å; F634-V649 HydrophobicContact CE1-CG1 3.45Å; F634-V649 VanDerWaalsContact CE1-CG1 3.45Å; F634-V649 HydrophobicContact CE2-CG1 4.09Å; F634-V649 HydrophobicContact CZ-CG1 3.22Å; S635-V649 WeakPolarHBondContact O-CA 3.22Å; F636-V649 HydrophobicContact CD1-CG2 4.13Å; F636-V649 HydrophobicContact CE1-CG2 4.41Å
650A98.8Very high90.1Very high2 Ų224.1 Ų24.12%0.01714%0.142CC..EExtended strand (participates in β ladder)trans-133.6151.9175.700000113.1F126 P359 F634 S635 I637F126-A650 CarbonylContact O-C 3.52Å; F126-A650 WeakPolarHBondContact O-CA 3.49Å; F126-A650 WeakPolarHBondContact O-CB 3.36Å; P359-A650 HydrophobicContact CG-CB 3.73Å; F634-A650 CarbonylContact C-O 3.49Å; F634-A650 WeakPolarHBondContact CA-O 3.33Å; S635-A650 PolarHBondContact N-O 3.28Å; S635-A650 PolarHBondContact O-N 3.27Å; I637-A650 HydrophobicContact CD1-CB 3.72Å
651M98.5Very high87Confident2 Ų231.5 Ų31.51%0.0118%0.182CC..EExtended strand (participates in β ladder)trans-138.6138.2179.5179176.268.600109.5F126 V511 P540 M616 Y618 V631 E633 F634 L653F126-M651 PolarHBondContact N-O 2.96Å; F126-M651 PolarHBondContact O-N 2.86Å; V511-M651 HydrophobicContact CG1-CE 4.26Å; V511-M651 HydrophobicContact CG2-CE 4.21Å; P540-M651 HydrophobicContact CG-SD 3.76Å; M616-M651 HydrophobicContact CG-CB 3.48Å; M616-M651 VanDerWaalsContact CG-CB 3.48Å; M616-M651 HydrophobicContact CG-CE 3.7Å; M616-M651 HydrophobicContact CG-CG 4.38Å; M616-M651 HydrophobicContact CG-SD 4.06Å; M616-M651 HydrophobicContact SD-CB 4.5Å; M616-M651 HydrophobicContact SD-CE 4.26Å; Y618-M651 HydrophobicContact CD1-CE 4.47Å; Y618-M651 HydrophobicContact CD1-SD 4.02Å; V631-M651 HydrophobicContact CG1-CG 4.2Å; V631-M651 HydrophobicContact CG2-SD 4.24Å; E633-M651 CarbonylContact O-C 3.6Å; E633-M651 WeakPolarHBondContact O-CA 3.44Å; F634-M651 HydrophobicContact CD2-CB 4.06Å; F634-M651 HydrophobicContact CD2-CG 4.24Å; F634-M651 HydrophobicContact CE2-CB 4.38Å; M651-L653 HydrophobicContact CE-CD1 3.94Å; M651-L653 HydrophobicContact CE-CD2 3.94Å; M651-L653 HydrophobicContact CE-CG 3.91Å; M651-L653 HydrophobicContact CG-CD2 4.09Å; M651-L653 HydrophobicContact CG-CG 4.38Å; M651-L653 HydrophobicContact SD-CD2 3.86Å; M651-L653 HydrophobicContact SD-CG 4.4Å
652R98.1Very high84.1Confident10 Ų1040.9 Ų40.94%0.03824%0.243CC..EExtended strand (participates in β ladder)trans-110.2125.2170.4-170.4179-62-76.3-2.9109F124 A360 E632 E633F124-R652 CarbonylContact O-C 2.93Å; F124-R652 VanDerWaalsContact O-CA 3.31Å; F124-R652 WeakPolarHBondContact O-CA 3.31Å; A360-R652 PolarHBondContact O-NH2 3.06Å; E632-R652 HydrophobicContact CB-CB 4.32Å; E632-R652 HydrophobicContact CB-CG 4.18Å; E632-R652 PolarHBondContact N-O 3.35Å; E632-R652 WeakPolarHBondContact OE2-CD 3.4Å; E633-R652 HydrophobicContact CB-CB 3.82Å; E633-R652 PolarHBondContact O-N 3.48Å; E633-R652 IonicContact OE2-CZ 3.48Å; E633-R652 IonicContact OE2-NE 3.89Å; E633-R652 PolarHBondContact OE2-NE 3.16Å; E633-R652 VanDerWaalsContact OE2-NE 3.14Å; E633-R652 IonicContact OE2-NH2 3.29Å
653L97Very high83.6Confident1 Ų142.2 Ų42.21%0.00525%0.247CC..EExtended strand (participates in β ladder)trans-106.8126.1175-64.7-179.1000109.7S123 F124 F126 F509 V511 Y618 V629 E630 V631 M651S123-L653 CarbonylContact C-O 3.59Å; S123-L653 VanDerWaalsContact CA-O 3.23Å; S123-L653 WeakPolarHBondContact CA-O 3.47Å; F124-L653 PolarHBondContact N-O 3.38Å; F124-L653 PolarHBondContact O-N 3.33Å; F126-L653 HydrophobicContact CD2-CD1 4.44Å; F126-L653 HydrophobicContact CD2-CG 4.37Å; F126-L653 HydrophobicContact CE2-CB 4.13Å; F126-L653 HydrophobicContact CE2-CD1 3.8Å; F126-L653 HydrophobicContact CE2-CG 3.96Å; F126-L653 HydrophobicContact CZ-CD1 4.38Å; F509-L653 HydrophobicContact CB-CD1 4.24Å; V511-L653 HydrophobicContact CG2-CD1 3.74Å; Y618-L653 HydrophobicContact CD1-CD2 4.49Å; Y618-L653 HydrophobicContact CD2-CD2 4.31Å; Y618-L653 HydrophobicContact CG-CD2 4.13Å; V629-L653 HydrophobicContact CG1-CB 4.14Å; V629-L653 HydrophobicContact CG1-CD1 4.04Å; V629-L653 HydrophobicContact CG1-CD2 4.16Å; V629-L653 HydrophobicContact CG1-CG 4.35Å; E630-L653 CarbonylContact O-C 3.47Å; E630-L653 WeakPolarHBondContact O-CA 3.42Å; V631-L653 HydrophobicContact CB-CD2 4.49Å; V631-L653 HydrophobicContact CG2-CD2 3.87Å; M651-L653 HydrophobicContact CE-CD1 3.94Å; M651-L653 HydrophobicContact CE-CD2 3.94Å; M651-L653 HydrophobicContact CE-CG 3.91Å; M651-L653 HydrophobicContact CG-CD2 4.09Å; M651-L653 HydrophobicContact CG-CG 4.38Å; M651-L653 HydrophobicContact SD-CD2 3.86Å; M651-L653 HydrophobicContact SD-CG 4.4Å
654M94.5Very high82.9Confident51 Ų5144.1 Ų44.125%0.25126%0.258SS..EExtended strand (participates in β ladder)trans-88.1124.3167.1177.261.17600108.9S123 V629 E630S123-M654 WeakPolarHBondContact OG-CE 3.24Å; V629-M654 WeakPolarHBondContact CA-O 3.5Å; E630-M654 PolarHBondContact N-O 3.06Å; E630-M654 PolarHBondContact O-N 2.72Å
655V93.9Very high82.1Confident0 Ų046.5 Ų46.50%027%0.273CS..EExtended strand (participates in β ladder)trans-106.6107.2171.8-173.20000107.8W115 G121 K122 F124 A508 W627 K628 V629W115-V655 HydrophobicContact CH2-CB 4.07Å; W115-V655 HydrophobicContact CH2-CG1 3.83Å; G121-V655 CarbonylContact C-O 3.59Å; G121-V655 WeakPolarHBondContact CA-O 3.31Å; K122-V655 PolarHBondContact N-O 3.16Å; K122-V655 PolarHBondContact O-N 2.66Å; F124-V655 HydrophobicContact CD2-CG2 3.77Å; F124-V655 HydrophobicContact CE2-CB 4.4Å; F124-V655 HydrophobicContact CE2-CG2 3.87Å; A508-V655 HydrophobicContact CB-CG1 4.41Å; A508-V655 HydrophobicContact CB-CG2 4.42Å; A508-V655 WeakPolarHBondContact O-CG2 3.49Å; W627-V655 HydrophobicContact CB-CG1 4.15Å; W627-V655 HydrophobicContact CD2-CG1 4.14Å; W627-V655 HydrophobicContact CE3-CG1 3.66Å; W627-V655 HydrophobicContact CG-CG1 4.38Å; W627-V655 HydrophobicContact CZ3-CG1 4.4Å; K628-V655 WeakPolarHBondContact O-CA 3.4Å; V629-V655 HydrophobicContact CG2-CB 4.46Å; V629-V655 HydrophobicContact CG2-CG1 4.2Å; V629-V655 HydrophobicContact CG2-CG2 4.01Å
656S89.3Confident81.3Confident24 Ų2448.8 Ų48.817%0.16829%0.286CS..EExtended strand (participates in β ladder)trans-104.3143.8179.460.30000111.7W627 K628W627-S656 CarbonylContact C-O 3.33Å; W627-S656 VanDerWaalsContact CA-O 3.23Å; W627-S656 WeakPolarHBondContact CA-O 3.2Å; K628-S656 PolarHBondContact N-O 3.14Å; K628-S656 PolarHBondContact O-N 3.12Å
657T80.7Confident80.2Confident20 Ų2051.3 Ų51.312%0.12330%0.301CS..  trans-93.52.6-171.857.10000114.4W115 A117 G119 W627W115-T657 HydrophobicContact CZ2-CG2 4.39Å; A117-T657 HydrophobicContact CB-CG2 4.44Å; G119-T657 PolarHBondContact O-OG1 3.42Å; W627-T657 HydrophobicContact CZ2-CG2 4.44Å
658G64.6Low79Confident59 Ų5954.5 Ų54.561%0.60832%0.321SS*.SBendtrans82.45.6171.100000117.2D660G658-D660 PolarHBondContact O-N 3.49Å
659E56.7Low77.5Confident161 Ų16158.2 Ų58.275%0.75234%0.343SS*.  trans-79.633.6176.9-67.7-169.7156.400114.5
660D45.8Very low75.9Confident124 Ų12462.6 Ų62.666%0.66337%0.368SS*.  trans-10273.2171.4-78.7-36000109.9G658G658-D660 PolarHBondContact O-N 3.49Å
661D32.1Very low74Confident160 Ų16067.7 Ų67.786%0.85640%0.398SS*.  trans-165.6104.8155.1-103.3-18.7000110.8
662P36.9Very low71.8Confident200 Ų20073.6 Ų73.6100%1.29943%0.433SS*.  trans-850159.830.9-30.7000114

Retrieved 662 of 662 residues in 272 ms (Link to these results)