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Phospholamban

Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.

AlphaFold DB (U3I3G3), UniProt , Accession A0A093HZ14, Species STRCA (Struthio camelus australis), Gene n/a, Length 52 aa.

						>A0A093HZ14_STRCA|A0A093HZ14
MEKVQYITRSALRRASTIEVNPQARQRLQELFVNFCLILICLLLICIIVMLL
					

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	53.6	Low	62.8	Low	213 Å²	213	130.6 Å²	130.6	100%	1.049	64%	0.638	S	S	*	*				0	-30.8	0	-81.1	-171.1	164.6	0	0	113.6	K3 V4	M1-K3 PolarHBondContact O-N 3.26Å; M1-V4 PolarHBondContact O-N 3.29Å
2	E	57.7	Low	62.9	Low	167 Å²	167	129.8 Å²	129.8	78%	0.78	64%	0.637	S	S	*	*	H	α-helix	trans	-59.6	-35	-176.5	-63.6	176.9	153.6	0	0	115.3	V4 Q5 Y6	E2-V4 VanDerWaalsContact C-N 3.32Å; E2-V4 PolarHBondContact O-N 3.08Å; E2-Q5 PolarHBondContact O-N 3.39Å; E2-Y6 PolarHBondContact O-N 3.36Å; E2-Y6 VanDerWaalsContact O-N 3.08Å
3	K	58.8	Low	62.8	Low	178 Å²	178	134.8 Å²	134.8	77%	0.774	65%	0.645	S	S	*	*	H	α-helix	trans	-63	-34.8	179.5	-70.4	-177	-179.1	179.5	0	113.2	M1 Y6 I7	M1-K3 PolarHBondContact O-N 3.26Å; K3-Y6 PolarHBondContact O-N 3.1Å; K3-I7 WeakPolarHBondContact O-CD1 3.38Å; K3-I7 VanDerWaalsContact O-CG1 3.26Å; K3-I7 WeakPolarHBondContact O-CG1 3.26Å; K3-I7 PolarHBondContact O-N 3.49Å; K3-I7 VanDerWaalsContact O-N 3.1Å
4	V	62.2	Low	62.5	Low	98 Å²	98	139.8 Å²	139.8	59%	0.594	65%	0.654	S	S	*	*	H	α-helix	trans	-72.3	-43.9	-179.7	-174.3	0	0	0	0	110.1	M1 E2 Y6 I7 T8	M1-V4 PolarHBondContact O-N 3.29Å; E2-V4 VanDerWaalsContact C-N 3.32Å; E2-V4 PolarHBondContact O-N 3.08Å; V4-Y6 VanDerWaalsContact C-N 3.28Å; V4-Y6 PolarHBondContact O-N 2.89Å; V4-I7 PolarHBondContact O-N 2.86Å; V4-T8 PolarHBondContact O-N 2.95Å; V4-T8 PolarHBondContact O-OG1 3.34Å
5	Q	61	Low	62.2	Low	129 Å²	129	134.4 Å²	134.4	60%	0.603	64%	0.643	S	S	*	*	H	α-helix	trans	-60.6	-36.6	174.8	-91.2	-176.5	-66.4	0	0	112.8	E2 R9	E2-Q5 PolarHBondContact O-N 3.39Å; Q5-R9 WeakPolarHBondContact O-CB 3.35Å; Q5-R9 PolarHBondContact O-N 3.49Å
6	Y	66.7	Low	61.9	Low	172 Å²	172	131.1 Å²	131.1	68%	0.675	64%	0.639	S	S	*	*	H	α-helix	trans	-65.6	-45.5	174.6	-175.9	-95.9	0	0	0	111.7	E2 K3 V4 T8 R9 S10	E2-Y6 PolarHBondContact O-N 3.36Å; E2-Y6 VanDerWaalsContact O-N 3.08Å; K3-Y6 PolarHBondContact O-N 3.1Å; V4-Y6 VanDerWaalsContact C-N 3.28Å; V4-Y6 PolarHBondContact O-N 2.89Å; Y6-T8 PolarHBondContact O-N 2.64Å; Y6-R9 PolarHBondContact O-N 3.5Å; Y6-S10 WeakPolarHBondContact O-CB 3.45Å; Y6-S10 PolarHBondContact O-N 3.37Å; Y6-S10 PolarHBondContact O-OG 3.49Å
7	I	68.3	Low	61.4	Low	111 Å²	111	129.8 Å²	129.8	57%	0.569	64%	0.64	S	S	*	*	H	α-helix	trans	-61.5	-46.3	176.6	-66.4	164.4	0	0	0	110.4	K3 V4 R9 S10 A11	K3-I7 WeakPolarHBondContact O-CD1 3.38Å; K3-I7 VanDerWaalsContact O-CG1 3.26Å; K3-I7 WeakPolarHBondContact O-CG1 3.26Å; K3-I7 PolarHBondContact O-N 3.49Å; K3-I7 VanDerWaalsContact O-N 3.1Å; V4-I7 PolarHBondContact O-N 2.86Å; I7-R9 PolarHBondContact O-N 3.48Å; I7-S10 PolarHBondContact O-N 3.22Å; I7-A11 WeakPolarHBondContact O-CB 3.47Å; I7-A11 PolarHBondContact O-N 3.19Å
8	T	68.4	Low	61.1	Low	85 Å²	85	129 Å²	129	52%	0.521	64%	0.638	S	S	.	*	H	α-helix	trans	-63	-42.7	178.6	-51.4	0	0	0	0	111.8	V4 Y6 S10 A11 L12	V4-T8 PolarHBondContact O-N 2.95Å; V4-T8 PolarHBondContact O-OG1 3.34Å; Y6-T8 PolarHBondContact O-N 2.64Å; T8-S10 VanDerWaalsContact C-N 3.34Å; T8-S10 PolarHBondContact O-N 2.92Å; T8-A11 PolarHBondContact O-N 2.85Å; T8-L12 WeakPolarHBondContact O-CB 3.32Å; T8-L12 PolarHBondContact O-N 2.89Å
9	R	67.8	Low	60.7	Low	187 Å²	187	131.1 Å²	131.1	71%	0.706	65%	0.645	S	S	*	*	H	α-helix	trans	-66.1	-34.9	175.1	-85.4	-176.5	170.4	-176.4	-1.7	112.8	Q5 Y6 I7 R13	Q5-R9 WeakPolarHBondContact O-CB 3.35Å; Q5-R9 PolarHBondContact O-N 3.49Å; Y6-R9 PolarHBondContact O-N 3.5Å; I7-R9 PolarHBondContact O-N 3.48Å; R9-R13 WeakPolarHBondContact O-CB 3.31Å; R9-R13 PolarHBondContact O-N 2.83Å
10	S	63.1	Low	60.5	Low	41 Å²	41	129.9 Å²	129.9	29%	0.287	65%	0.646	S	S	.	*	H	α-helix	trans	-69.5	-43.9	177.6	-54.6	0	0	0	0	111.4	Y6 I7 T8 R13 R14	Y6-S10 WeakPolarHBondContact O-CB 3.45Å; Y6-S10 PolarHBondContact O-N 3.37Å; Y6-S10 PolarHBondContact O-OG 3.49Å; I7-S10 PolarHBondContact O-N 3.22Å; T8-S10 VanDerWaalsContact C-N 3.34Å; T8-S10 PolarHBondContact O-N 2.92Å; S10-R13 PolarHBondContact O-N 3.48Å; S10-R14 WeakPolarHBondContact O-CG 3.41Å; S10-R14 PolarHBondContact O-N 2.98Å
11	A	63.5	Low	60.5	Low	56 Å²	56	127.4 Å²	127.4	46%	0.463	64%	0.635	S	S	.	*	H	α-helix	trans	-65.5	-42	174.5	0	0	0	0	0	111.4	I7 T8 R14 A15	I7-A11 WeakPolarHBondContact O-CB 3.47Å; I7-A11 PolarHBondContact O-N 3.19Å; T8-A11 PolarHBondContact O-N 2.85Å; A11-R14 PolarHBondContact O-N 3.37Å; A11-A15 WeakPolarHBondContact O-CB 3.18Å; A11-A15 PolarHBondContact O-N 2.9Å
12	L	64.3	Low	61	Low	120 Å²	120	121.8 Å²	121.8	63%	0.628	61%	0.614	S	S	*	*	H	α-helix	trans	-65.1	-41.1	176.8	-171.8	66.2	0	0	0	111.9	T8 A15 S16	T8-L12 WeakPolarHBondContact O-CB 3.32Å; T8-L12 PolarHBondContact O-N 2.89Å; L12-A15 PolarHBondContact O-N 3.11Å; L12-S16 WeakPolarHBondContact O-CB 3.48Å; L12-S16 PolarHBondContact O-N 2.94Å; L12-S16 PolarHBondContact O-OG 2.91Å
13	R	61	Low	61.7	Low	195 Å²	195	120.1 Å²	120.1	74%	0.736	61%	0.607	S	S	*	*	H	α-helix	trans	-62.5	-47	172.8	-96.6	-174.5	168	-173.4	-3.7	111.5	R9 S10 A15 S16 T17	R9-R13 WeakPolarHBondContact O-CB 3.31Å; R9-R13 PolarHBondContact O-N 2.83Å; S10-R13 PolarHBondContact O-N 3.48Å; R13-A15 VanDerWaalsContact C-N 3.28Å; R13-A15 PolarHBondContact O-N 2.85Å; R13-S16 WeakPolarHBondContact CA-OG 3.35Å; R13-S16 PolarHBondContact O-N 2.74Å; R13-S16 VanDerWaalsContact O-N 3.11Å; R13-S16 PolarHBondContact O-OG 3.37Å; R13-T17 PolarHBondContact O-N 3.33Å; R13-T17 PolarHBondContact O-OG1 2.89Å
14	R	59.1	Low	62.5	Low	205 Å²	205	113.9 Å²	113.9	77%	0.774	59%	0.588	S	S	*	*	H	α-helix	trans	-60.3	-37.7	175.4	-77.5	-178	175.5	177.1	-0.9	112.2	S10 A11 I18	S10-R14 WeakPolarHBondContact O-CG 3.41Å; S10-R14 PolarHBondContact O-N 2.98Å; A11-R14 PolarHBondContact O-N 3.37Å; R14-I18 VanDerWaalsContact O-CG1 3.31Å; R14-I18 WeakPolarHBondContact O-CG1 3.37Å; R14-I18 PolarHBondContact O-N 3.33Å
15	A	57.9	Low	63.3	Low	59 Å²	59	117.6 Å²	117.6	49%	0.488	59%	0.591	S	S	.	*	H	α-helix	trans	-68.7	-36.7	174.1	0	0	0	0	0	112.5	A11 L12 R13 I18	A11-A15 WeakPolarHBondContact O-CB 3.18Å; A11-A15 PolarHBondContact O-N 2.9Å; L12-A15 PolarHBondContact O-N 3.11Å; R13-A15 VanDerWaalsContact C-N 3.28Å; R13-A15 PolarHBondContact O-N 2.85Å; A15-I18 WeakPolarHBondContact O-CB 3.42Å; A15-I18 PolarHBondContact O-N 3.38Å
16	S	57	Low	64.3	Low	82 Å²	82	116.9 Å²	116.9	57%	0.573	59%	0.588	S	S	*	*	H	α-helix	trans	-74.4	-27.8	178.7	67.4	0	0	0	0	114.2	L12 R13 I18	L12-S16 WeakPolarHBondContact O-CB 3.48Å; L12-S16 PolarHBondContact O-N 2.94Å; L12-S16 PolarHBondContact O-OG 2.91Å; R13-S16 WeakPolarHBondContact CA-OG 3.35Å; R13-S16 PolarHBondContact O-N 2.74Å; R13-S16 VanDerWaalsContact O-N 3.11Å; R13-S16 PolarHBondContact O-OG 3.37Å; S16-I18 VanDerWaalsContact C-N 3.29Å
17	T	54.2	Low	65.1	Low	109 Å²	109	117 Å²	117	67%	0.669	59%	0.587	S	S	*	*	T	Hydrogen-bonded Turn	trans	-85.9	-2.9	174.9	-35.8	0	0	0	0	112.1	R13 E19	R13-T17 PolarHBondContact O-N 3.33Å; R13-T17 PolarHBondContact O-OG1 2.89Å; T17-E19 PolarHBondContact O-N 3.32Å
18	I	55.6	Low	66.1	Low	115 Å²	115	117.3 Å²	117.3	59%	0.59	59%	0.589	S	S	*	*			trans	-75.3	68.9	157.5	-58.4	161.9	0	0	0	105.5	R14 A15 S16 V20	R14-I18 VanDerWaalsContact O-CG1 3.31Å; R14-I18 WeakPolarHBondContact O-CG1 3.37Å; R14-I18 PolarHBondContact O-N 3.33Å; A15-I18 WeakPolarHBondContact O-CB 3.42Å; A15-I18 PolarHBondContact O-N 3.38Å; S16-I18 VanDerWaalsContact C-N 3.29Å; I18-V20 PolarHBondContact O-N 3.07Å
19	E	52.4	Low	67	Low	168 Å²	168	119 Å²	119	79%	0.785	59%	0.591	S	S	*	*			trans	-46.8	120.6	150.5	-72.8	-176.4	121.9	0	0	105.1	T17 N21	T17-E19 PolarHBondContact O-N 3.32Å; E19-N21 VanDerWaalsContact C-N 3.25Å; E19-N21 PolarHBondContact O-N 2.64Å
20	V	58.5	Low	68.2	Low	107 Å²	107	114.1 Å²	114.1	65%	0.648	58%	0.577	S	S	*	*			trans	-51.6	90.7	-170.9	-179.9	0	0	0	0	108.4	I18 P22 R25	I18-V20 PolarHBondContact O-N 3.07Å; V20-P22 WeakPolarHBondContact O-CD 3.4Å; V20-R25 HydrophobicContact CG1-CB 4.4Å
21	N	58.6	Low	69.7	Low	79 Å²	79	117.8 Å²	117.8	42%	0.422	59%	0.592	S	S	.	*			trans	-61.7	112.7	-178.4	-179.5	-3.1	0	0	0	104.8	E19 Q23 A24 R25	E19-N21 VanDerWaalsContact C-N 3.25Å; E19-N21 PolarHBondContact O-N 2.64Å; N21-Q23 PolarHBondContact O-N 2.94Å; N21-Q23 PolarHBondContact OD1-N 3.48Å; N21-A24 HydrophobicContact CB-CB 4.09Å; N21-A24 WeakPolarHBondContact O-CA 3.32Å; N21-A24 WeakPolarHBondContact O-CB 3.26Å; N21-A24 PolarHBondContact O-N 3.5Å; N21-R25 PolarHBondContact O-N 3.23Å
22	P	66.1	Low	71.1	Confident	95 Å²	95	121.7 Å²	121.7	62%	0.617	60%	0.599	S	S	*	*	H	α-helix	trans	-57.8	-29.8	-171.2	20.4	-32.1	0	0	0	110.9	V20 R25 Q26	V20-P22 WeakPolarHBondContact O-CD 3.4Å; P22-R25 PolarHBondContact O-N 3.46Å; P22-Q26 WeakPolarHBondContact O-CB 3.14Å; P22-Q26 PolarHBondContact O-N 3.04Å
23	Q	70.8	Confident	72.6	Confident	132 Å²	132	119.4 Å²	119.4	62%	0.617	59%	0.59	S	S	*	*	H	α-helix	trans	-64.5	-42.7	172.7	-64.1	-176.9	-14	0	0	112.6	N21 R25 Q26 R27	N21-Q23 PolarHBondContact O-N 2.94Å; N21-Q23 PolarHBondContact OD1-N 3.48Å; Q23-R25 VanDerWaalsContact C-N 3.33Å; Q23-R25 PolarHBondContact O-N 2.94Å; Q23-Q26 PolarHBondContact O-N 3.39Å; Q23-R27 WeakPolarHBondContact O-CB 3.42Å; Q23-R27 VanDerWaalsContact O-CG 3.24Å; Q23-R27 WeakPolarHBondContact O-CG 3.47Å; Q23-R27 PolarHBondContact O-N 3.44Å
24	A	75.7	Confident	74.3	Confident	46 Å²	46	114.6 Å²	114.6	38%	0.38	58%	0.579	S	S	.	*	H	α-helix	trans	-64.1	-40.3	177.8	0	0	0	0	0	111.4	N21 Q26 R27 L28	N21-A24 HydrophobicContact CB-CB 4.09Å; N21-A24 WeakPolarHBondContact O-CA 3.32Å; N21-A24 WeakPolarHBondContact O-CB 3.26Å; N21-A24 PolarHBondContact O-N 3.5Å; A24-Q26 VanDerWaalsContact C-N 3.34Å; A24-Q26 PolarHBondContact O-N 2.82Å; A24-R27 PolarHBondContact O-N 2.85Å; A24-L28 WeakPolarHBondContact O-CB 3.24Å; A24-L28 VanDerWaalsContact O-CG 3.26Å; A24-L28 WeakPolarHBondContact O-CG 3.3Å; A24-L28 PolarHBondContact O-N 2.89Å
25	R	79	Confident	76.1	Confident	176 Å²	176	110.6 Å²	110.6	66%	0.664	57%	0.567	S	S	*	*	H	α-helix	trans	-61.4	-43.7	173.5	-176.5	178.3	175.3	-170.7	-1.3	111.5	V20 N21 P22 Q23 L28 Q29	V20-R25 HydrophobicContact CG1-CB 4.4Å; N21-R25 PolarHBondContact O-N 3.23Å; P22-R25 PolarHBondContact O-N 3.46Å; Q23-R25 VanDerWaalsContact C-N 3.33Å; Q23-R25 PolarHBondContact O-N 2.94Å; R25-L28 PolarHBondContact O-N 2.99Å; R25-Q29 WeakPolarHBondContact O-CB 3.48Å; R25-Q29 PolarHBondContact O-N 3.17Å
26	Q	82.1	Confident	78	Confident	115 Å²	115	109.7 Å²	109.7	54%	0.537	56%	0.557	S	S	.	*	H	α-helix	trans	-66.5	-41.8	179.6	-156.4	167.9	6.8	0	0	111.8	P22 Q23 A24 Q29 E30	P22-Q26 WeakPolarHBondContact O-CB 3.14Å; P22-Q26 PolarHBondContact O-N 3.04Å; Q23-Q26 PolarHBondContact O-N 3.39Å; A24-Q26 VanDerWaalsContact C-N 3.34Å; A24-Q26 PolarHBondContact O-N 2.82Å; Q26-Q29 PolarHBondContact O-N 3.14Å; Q26-E30 WeakPolarHBondContact O-CG 3.37Å; Q26-E30 PolarHBondContact O-N 3.35Å
27	R	84.9	Confident	79.9	Confident	173 Å²	173	110.2 Å²	110.2	65%	0.653	55%	0.553	S	S	*	*	H	α-helix	trans	-62.5	-41.9	173.5	-68.4	-58.9	-174.3	-172.2	3.7	112.7	Q23 A24 Q29 E30 L31	Q23-R27 WeakPolarHBondContact O-CB 3.42Å; Q23-R27 VanDerWaalsContact O-CG 3.24Å; Q23-R27 WeakPolarHBondContact O-CG 3.47Å; Q23-R27 PolarHBondContact O-N 3.44Å; A24-R27 PolarHBondContact O-N 2.85Å; R27-Q29 VanDerWaalsContact C-N 3.32Å; R27-E30 IonicContact NH1-OE2 3.14Å; R27-E30 PolarHBondContact NH1-OE2 2.92Å; R27-E30 VanDerWaalsContact NH1-OE2 3.14Å; R27-E30 PolarHBondContact O-N 3.38Å; R27-L31 WeakPolarHBondContact O-CB 3.4Å; R27-L31 PolarHBondContact O-N 3.25Å
28	L	88.7	Confident	82	Confident	118 Å²	118	109.8 Å²	109.8	62%	0.618	55%	0.546	S	S	*	.	H	α-helix	trans	-66.2	-37.4	175.7	-72.9	171.7	0	0	0	111.6	A24 R25 L31 F32	A24-L28 WeakPolarHBondContact O-CB 3.24Å; A24-L28 VanDerWaalsContact O-CG 3.26Å; A24-L28 WeakPolarHBondContact O-CG 3.3Å; A24-L28 PolarHBondContact O-N 2.89Å; R25-L28 PolarHBondContact O-N 2.99Å; L28-L31 PolarHBondContact O-N 3.29Å; L28-F32 VanDerWaalsContact O-CB 3.3Å; L28-F32 WeakPolarHBondContact O-CB 3.39Å; L28-F32 PolarHBondContact O-N 3.43Å
29	Q	87.3	Confident	84	Confident	120 Å²	120	108.3 Å²	108.3	56%	0.561	54%	0.538	S	S	*	.	H	α-helix	trans	-66.5	-45.9	175.8	-170.5	175.1	-0.5	0	0	111.5	R25 Q26 R27 L31 F32 V33	R25-Q29 WeakPolarHBondContact O-CB 3.48Å; R25-Q29 PolarHBondContact O-N 3.17Å; Q26-Q29 PolarHBondContact O-N 3.14Å; R27-Q29 VanDerWaalsContact C-N 3.32Å; Q29-L31 VanDerWaalsContact C-N 3.33Å; Q29-L31 PolarHBondContact O-N 3.48Å; Q29-F32 PolarHBondContact O-N 2.9Å; Q29-V33 VanDerWaalsContact O-CG2 3.29Å; Q29-V33 WeakPolarHBondContact O-CG2 3.27Å; Q29-V33 PolarHBondContact O-N 3.44Å
30	E	93.1	Very high	86.1	Confident	86 Å²	86	105 Å²	105	40%	0.402	53%	0.525	S	S	.	.	H	α-helix	trans	-57	-46.7	173.2	-76.4	172.7	-177.4	0	0	111.3	Q26 R27 F32 V33 N34	Q26-E30 WeakPolarHBondContact O-CG 3.37Å; Q26-E30 PolarHBondContact O-N 3.35Å; R27-E30 IonicContact NH1-OE2 3.14Å; R27-E30 PolarHBondContact NH1-OE2 2.92Å; R27-E30 VanDerWaalsContact NH1-OE2 3.14Å; R27-E30 PolarHBondContact O-N 3.38Å; E30-F32 PolarHBondContact O-N 3Å; E30-V33 PolarHBondContact O-N 3.47Å; E30-N34 WeakPolarHBondContact O-CB 3.36Å; E30-N34 VanDerWaalsContact O-CG 3.31Å; E30-N34 PolarHBondContact O-N 3.02Å; E30-N34 PolarHBondContact O-ND2 3.29Å
31	L	93.4	Very high	88	Confident	118 Å²	118	103.2 Å²	103.2	62%	0.618	52%	0.517	S	S	*	.	H	α-helix	trans	-62.7	-43.4	179.2	-166.9	72	0	0	0	111.6	R27 L28 Q29 N34 F35	R27-L31 WeakPolarHBondContact O-CB 3.4Å; R27-L31 PolarHBondContact O-N 3.25Å; L28-L31 PolarHBondContact O-N 3.29Å; Q29-L31 VanDerWaalsContact C-N 3.33Å; Q29-L31 PolarHBondContact O-N 3.48Å; L31-N34 PolarHBondContact O-N 3.37Å; L31-F35 VanDerWaalsContact O-CB 3.27Å; L31-F35 WeakPolarHBondContact O-CB 3.42Å; L31-F35 PolarHBondContact O-N 3.46Å
32	F	94.5	Very high	89.9	Confident	137 Å²	137	104 Å²	104	60%	0.601	52%	0.521	S	S	*	.	H	α-helix	trans	-66.3	-43.8	179.7	-171.3	-96.8	0	0	0	111.9	L28 Q29 E30 F35 C36	L28-F32 VanDerWaalsContact O-CB 3.3Å; L28-F32 WeakPolarHBondContact O-CB 3.39Å; L28-F32 PolarHBondContact O-N 3.43Å; Q29-F32 PolarHBondContact O-N 2.9Å; E30-F32 PolarHBondContact O-N 3Å; F32-F35 PolarHBondContact O-N 3.45Å; F32-C36 WeakPolarHBondContact O-CB 3.48Å; F32-C36 PolarHBondContact O-N 2.95Å; F32-C36 PolarHBondContact O-SG 3.37Å; F32-C36 VanDerWaalsContact O-SG 3.37Å
33	V	96	Very high	91.4	Very high	72 Å²	72	105 Å²	105	44%	0.436	52%	0.52	S	S	.	.	H	α-helix	trans	-62.2	-47.3	176.8	171.8	0	0	0	0	110.4	Q29 E30 F35 C36 L37	Q29-V33 VanDerWaalsContact O-CG2 3.29Å; Q29-V33 WeakPolarHBondContact O-CG2 3.27Å; Q29-V33 PolarHBondContact O-N 3.44Å; E30-V33 PolarHBondContact O-N 3.47Å; V33-F35 VanDerWaalsContact C-N 3.33Å; V33-F35 PolarHBondContact O-N 3.45Å; V33-C36 PolarHBondContact O-N 2.9Å; V33-L37 HydrophobicContact CG1-CD1 4Å; V33-L37 HydrophobicContact CG1-CG 4.5Å; V33-L37 WeakPolarHBondContact O-CG 3.29Å; V33-L37 PolarHBondContact O-N 3.35Å
34	N	95.6	Very high	92.6	Very high	94 Å²	94	103.2 Å²	103.2	50%	0.503	51%	0.514	S	S	.	.	H	α-helix	trans	-61.6	-42	177.7	-75.2	-16.4	0	0	0	111.9	E30 L31 L37 I38	E30-N34 WeakPolarHBondContact O-CB 3.36Å; E30-N34 VanDerWaalsContact O-CG 3.31Å; E30-N34 PolarHBondContact O-N 3.02Å; E30-N34 PolarHBondContact O-ND2 3.29Å; L31-N34 PolarHBondContact O-N 3.37Å; N34-L37 PolarHBondContact O-N 3.49Å; N34-I38 VanDerWaalsContact O-CG1 3.29Å; N34-I38 WeakPolarHBondContact O-CG1 3.42Å; N34-I38 PolarHBondContact O-N 2.96Å
35	F	96.9	Very high	93.7	Very high	121 Å²	121	105.7 Å²	105.7	53%	0.531	52%	0.52	S	S	.	.	H	α-helix	trans	-62.7	-45.2	176.8	-178.4	-105.9	0	0	0	112.2	L31 F32 V33 L37 I38 L39	L31-F35 VanDerWaalsContact O-CB 3.27Å; L31-F35 WeakPolarHBondContact O-CB 3.42Å; L31-F35 PolarHBondContact O-N 3.46Å; F32-F35 PolarHBondContact O-N 3.45Å; V33-F35 VanDerWaalsContact C-N 3.33Å; V33-F35 PolarHBondContact O-N 3.45Å; F35-L37 PolarHBondContact O-N 3.48Å; F35-I38 PolarHBondContact O-N 3.45Å; F35-L39 HydrophobicContact CD1-CD1 3.85Å; F35-L39 HydrophobicContact CD1-CG 4.5Å; F35-L39 HydrophobicContact CE1-CD1 3.35Å; F35-L39 HydrophobicContact CE1-CG 4.13Å; F35-L39 HydrophobicContact CZ-CD1 3.78Å; F35-L39 HydrophobicContact CZ-CD2 4.43Å; F35-L39 HydrophobicContact CZ-CG 4.17Å; F35-L39 PolarHBondContact O-N 2.87Å
36	C	97.4	Very high	94.5	Very high	41 Å²	41	101 Å²	101	28%	0.277	51%	0.514	S	S	.	.	H	α-helix	trans	-62.4	-41.5	176	-74.7	0	0	0	0	112.2	F32 V33 I38 L39 I40	F32-C36 WeakPolarHBondContact O-CB 3.48Å; F32-C36 PolarHBondContact O-N 2.95Å; F32-C36 PolarHBondContact O-SG 3.37Å; F32-C36 VanDerWaalsContact O-SG 3.37Å; V33-C36 PolarHBondContact O-N 2.9Å; C36-I38 VanDerWaalsContact C-N 3.35Å; C36-I38 PolarHBondContact O-N 2.92Å; C36-L39 PolarHBondContact O-N 2.9Å; C36-I40 VanDerWaalsContact O-CG1 3.29Å; C36-I40 WeakPolarHBondContact O-CG1 3.47Å; C36-I40 PolarHBondContact O-N 2.97Å
37	L	97.3	Very high	95.2	Very high	92 Å²	92	100 Å²	100	48%	0.482	51%	0.51	S	S	.	.	H	α-helix	trans	-60.5	-44.3	175.6	-76.2	169.2	0	0	0	111.6	V33 N34 F35 L39 I40 C41	V33-L37 HydrophobicContact CG1-CD1 4Å; V33-L37 HydrophobicContact CG1-CG 4.5Å; V33-L37 WeakPolarHBondContact O-CG 3.29Å; V33-L37 PolarHBondContact O-N 3.35Å; N34-L37 PolarHBondContact O-N 3.49Å; F35-L37 PolarHBondContact O-N 3.48Å; L37-L39 VanDerWaalsContact C-N 3.35Å; L37-L39 PolarHBondContact O-N 3.22Å; L37-I40 PolarHBondContact O-N 3.31Å; L37-C41 PolarHBondContact O-N 2.92Å; L37-C41 PolarHBondContact O-SG 3.3Å
38	I	97.7	Very high	95.8	Very high	101 Å²	101	96.9 Å²	96.9	52%	0.518	51%	0.506	S	S	.	.	H	α-helix	trans	-60.7	-45.6	176.4	-68.3	164.9	0	0	0	110.7	N34 F35 C36 I40 C41 L42	N34-I38 VanDerWaalsContact O-CG1 3.29Å; N34-I38 WeakPolarHBondContact O-CG1 3.42Å; N34-I38 PolarHBondContact O-N 2.96Å; F35-I38 PolarHBondContact O-N 3.45Å; C36-I38 VanDerWaalsContact C-N 3.35Å; C36-I38 PolarHBondContact O-N 2.92Å; I38-I40 VanDerWaalsContact C-N 3.35Å; I38-I40 PolarHBondContact O-N 2.93Å; I38-C41 WeakPolarHBondContact O-CB 3.44Å; I38-C41 PolarHBondContact O-N 3.3Å; I38-L42 HydrophobicContact CG2-CD1 4.09Å; I38-L42 HydrophobicContact CG2-CG 4.45Å; I38-L42 WeakPolarHBondContact O-CG 3.38Å; I38-L42 PolarHBondContact O-N 3Å
39	L	97.9	Very high	96.2	Very high	83 Å²	83	95.4 Å²	95.4	44%	0.435	50%	0.501	S	S	.	.	H	α-helix	trans	-60.6	-43.3	177.8	-76.6	175.6	0	0	0	112.3	F35 C36 L37 L42 L43	F35-L39 HydrophobicContact CD1-CD1 3.85Å; F35-L39 HydrophobicContact CD1-CG 4.5Å; F35-L39 HydrophobicContact CE1-CD1 3.35Å; F35-L39 HydrophobicContact CE1-CG 4.13Å; F35-L39 HydrophobicContact CZ-CD1 3.78Å; F35-L39 HydrophobicContact CZ-CD2 4.43Å; F35-L39 HydrophobicContact CZ-CG 4.17Å; F35-L39 PolarHBondContact O-N 2.87Å; C36-L39 PolarHBondContact O-N 2.9Å; L37-L39 VanDerWaalsContact C-N 3.35Å; L37-L39 PolarHBondContact O-N 3.22Å; L39-L42 PolarHBondContact O-N 3.48Å; L39-L43 WeakPolarHBondContact O-CB 3.29Å; L39-L43 PolarHBondContact O-N 3.38Å
40	I	97.9	Very high	96.5	Very high	98 Å²	98	97.3 Å²	97.3	50%	0.503	51%	0.512	S	S	.	.	H	α-helix	trans	-62.2	-45.1	176.8	-68.2	165.2	0	0	0	110.3	C36 L37 I38 L42 L43 L44	C36-I40 VanDerWaalsContact O-CG1 3.29Å; C36-I40 WeakPolarHBondContact O-CG1 3.47Å; C36-I40 PolarHBondContact O-N 2.97Å; L37-I40 PolarHBondContact O-N 3.31Å; I38-I40 VanDerWaalsContact C-N 3.35Å; I38-I40 PolarHBondContact O-N 2.93Å; I40-L42 PolarHBondContact O-N 2.93Å; I40-L43 WeakPolarHBondContact O-CB 3.3Å; I40-L43 PolarHBondContact O-N 3.33Å; I40-L44 HydrophobicContact CG2-CD1 4.07Å; I40-L44 HydrophobicContact CG2-CG 4.45Å; I40-L44 WeakPolarHBondContact O-CG 3.29Å; I40-L44 PolarHBondContact O-N 3.34Å
41	C	97.7	Very high	96.2	Very high	71 Å²	71	100.6 Å²	100.6	48%	0.48	53%	0.532	S	S	.	.	H	α-helix	trans	-59	-45.3	176.4	-71.8	0	0	0	0	112	L37 I38 L43 L44 I45	L37-C41 PolarHBondContact O-N 2.92Å; L37-C41 PolarHBondContact O-SG 3.3Å; I38-C41 WeakPolarHBondContact O-CB 3.44Å; I38-C41 PolarHBondContact O-N 3.3Å; C41-L43 VanDerWaalsContact C-N 3.33Å; C41-L43 PolarHBondContact O-N 3.49Å; C41-L44 PolarHBondContact O-N 3.28Å; C41-I45 WeakPolarHBondContact O-CG1 3.5Å; C41-I45 PolarHBondContact O-N 3.26Å
42	L	97.6	Very high	95.7	Very high	96 Å²	96	104.6 Å²	104.6	50%	0.503	55%	0.553	S	S	.	*	H	α-helix	trans	-62.6	-41.2	176.4	-70.6	173.4	0	0	0	111.7	I38 L39 I40 L44 I45 C46	I38-L42 HydrophobicContact CG2-CD1 4.09Å; I38-L42 HydrophobicContact CG2-CG 4.45Å; I38-L42 WeakPolarHBondContact O-CG 3.38Å; I38-L42 PolarHBondContact O-N 3Å; L39-L42 PolarHBondContact O-N 3.48Å; I40-L42 PolarHBondContact O-N 2.93Å; L42-L44 VanDerWaalsContact C-N 3.34Å; L42-L44 PolarHBondContact O-N 3.45Å; L42-I45 PolarHBondContact O-N 3.45Å; L42-C46 PolarHBondContact O-N 3.31Å; L42-C46 PolarHBondContact O-SG 2.93Å; L42-C46 VanDerWaalsContact O-SG 3.35Å
43	L	97.4	Very high	95.8	Very high	116 Å²	116	103 Å²	103	61%	0.607	55%	0.55	S	S	*	*	H	α-helix	trans	-62.3	-43.5	177.7	-150	103.7	0	0	0	111.3	L39 I40 C41 C46 I47	L39-L43 WeakPolarHBondContact O-CB 3.29Å; L39-L43 PolarHBondContact O-N 3.38Å; I40-L43 WeakPolarHBondContact O-CB 3.3Å; I40-L43 PolarHBondContact O-N 3.33Å; C41-L43 VanDerWaalsContact C-N 3.33Å; C41-L43 PolarHBondContact O-N 3.49Å; L43-C46 WeakPolarHBondContact O-CB 3.21Å; L43-C46 PolarHBondContact O-N 3.47Å; L43-I47 HydrophobicContact CD2-CD1 4.18Å; L43-I47 VanDerWaalsContact O-CG1 3.32Å; L43-I47 WeakPolarHBondContact O-CG1 3.32Å; L43-I47 PolarHBondContact O-N 2.94Å
44	L	97.3	Very high	95.8	Very high	94 Å²	94	104.6 Å²	104.6	49%	0.492	56%	0.556	S	S	.	*	H	α-helix	trans	-62.6	-42.6	176.3	-73.8	170.9	0	0	0	111.8	I40 C41 L42 C46 I47 I48	I40-L44 HydrophobicContact CG2-CD1 4.07Å; I40-L44 HydrophobicContact CG2-CG 4.45Å; I40-L44 WeakPolarHBondContact O-CG 3.29Å; I40-L44 PolarHBondContact O-N 3.34Å; C41-L44 PolarHBondContact O-N 3.28Å; L42-L44 VanDerWaalsContact C-N 3.34Å; L42-L44 PolarHBondContact O-N 3.45Å; L44-C46 VanDerWaalsContact C-N 3.34Å; L44-C46 PolarHBondContact O-N 3.2Å; L44-I47 PolarHBondContact O-N 3.23Å; L44-I48 VanDerWaalsContact O-CG1 3.3Å; L44-I48 WeakPolarHBondContact O-CG1 3.32Å; L44-I48 PolarHBondContact O-N 3.48Å
45	I	97.6	Very high	95.8	Very high	97 Å²	97	105.2 Å²	105.2	50%	0.497	56%	0.559	S	S	.	*	H	α-helix	trans	-60.1	-46.6	174.8	-67.5	165	0	0	0	110.2	C41 L42 I47 I48 V49	C41-I45 WeakPolarHBondContact O-CG1 3.5Å; C41-I45 PolarHBondContact O-N 3.26Å; L42-I45 PolarHBondContact O-N 3.45Å; I45-I47 VanDerWaalsContact C-N 3.3Å; I45-I47 PolarHBondContact O-N 3.31Å; I45-I48 PolarHBondContact O-N 3.48Å; I45-V49 HydrophobicContact CG2-CG2 4.32Å; I45-V49 VanDerWaalsContact O-CG2 3.3Å; I45-V49 WeakPolarHBondContact O-CG2 3.32Å; I45-V49 PolarHBondContact O-N 2.96Å
46	C	96.9	Very high	95.7	Very high	79 Å²	79	104.2 Å²	104.2	53%	0.534	56%	0.561	S	S	.	*	H	α-helix	trans	-58.9	-41.5	176.3	-70.3	0	0	0	0	112.2	L42 L43 L44 V49 M50	L42-C46 PolarHBondContact O-N 3.31Å; L42-C46 PolarHBondContact O-SG 2.93Å; L42-C46 VanDerWaalsContact O-SG 3.35Å; L43-C46 WeakPolarHBondContact O-CB 3.21Å; L43-C46 PolarHBondContact O-N 3.47Å; L44-C46 VanDerWaalsContact C-N 3.34Å; L44-C46 PolarHBondContact O-N 3.2Å; C46-V49 PolarHBondContact O-N 2.89Å; C46-M50 WeakPolarHBondContact O-CB 3.3Å; C46-M50 WeakPolarHBondContact O-CG 3.38Å; C46-M50 PolarHBondContact O-N 3.21Å
47	I	97.1	Very high	95.6	Very high	92 Å²	92	108.2 Å²	108.2	47%	0.472	58%	0.579	S	S	.	*	H	α-helix	trans	-63.3	-46.3	176.3	-69	165.6	0	0	0	110.7	L43 L44 I45 V49 M50 L51	L43-I47 HydrophobicContact CD2-CD1 4.18Å; L43-I47 VanDerWaalsContact O-CG1 3.32Å; L43-I47 WeakPolarHBondContact O-CG1 3.32Å; L43-I47 PolarHBondContact O-N 2.94Å; L44-I47 PolarHBondContact O-N 3.23Å; I45-I47 VanDerWaalsContact C-N 3.3Å; I45-I47 PolarHBondContact O-N 3.31Å; I47-V49 VanDerWaalsContact C-N 3.31Å; I47-V49 PolarHBondContact O-N 2.91Å; I47-M50 PolarHBondContact O-N 3.42Å; I47-L51 VanDerWaalsContact O-CB 3.32Å; I47-L51 WeakPolarHBondContact O-CB 3.43Å; I47-L51 PolarHBondContact O-N 2.94Å
48	I	96.8	Very high	95.5	Very high	108 Å²	108	109.3 Å²	109.3	55%	0.554	59%	0.585	S	S	*	*	H	α-helix	trans	-59.2	-44.9	177.8	-69.3	167.6	0	0	0	110.3	L44 I45 M50 L51 L52	L44-I48 VanDerWaalsContact O-CG1 3.3Å; L44-I48 WeakPolarHBondContact O-CG1 3.32Å; L44-I48 PolarHBondContact O-N 3.48Å; I45-I48 PolarHBondContact O-N 3.48Å; I48-M50 VanDerWaalsContact C-N 3.33Å; I48-M50 PolarHBondContact O-N 3.41Å; I48-L51 PolarHBondContact O-N 3Å; I48-L52 WeakPolarHBondContact O-CB 3.36Å; I48-L52 PolarHBondContact O-N 3.28Å
49	V	96.7	Very high	95.4	Very high	87 Å²	87	109.9 Å²	109.9	53%	0.527	59%	0.59	S	S	.	*	H	α-helix	trans	-65.7	-34.2	178.3	171.2	0	0	0	0	112.3	I45 C46 I47	I45-V49 HydrophobicContact CG2-CG2 4.32Å; I45-V49 VanDerWaalsContact O-CG2 3.3Å; I45-V49 WeakPolarHBondContact O-CG2 3.32Å; I45-V49 PolarHBondContact O-N 2.96Å; C46-V49 PolarHBondContact O-N 2.89Å; I47-V49 VanDerWaalsContact C-N 3.31Å; I47-V49 PolarHBondContact O-N 2.91Å
50	M	93.5	Very high	95.2	Very high	160 Å²	160	111.9 Å²	111.9	79%	0.788	60%	0.602	S	S	*	*	H	α-helix	trans	-77.1	-24.5	176.8	-71.7	-74.1	125.7	0	0	113	C46 I47 I48	C46-M50 WeakPolarHBondContact O-CB 3.3Å; C46-M50 WeakPolarHBondContact O-CG 3.38Å; C46-M50 PolarHBondContact O-N 3.21Å; I47-M50 PolarHBondContact O-N 3.42Å; I48-M50 VanDerWaalsContact C-N 3.33Å; I48-M50 PolarHBondContact O-N 3.41Å
51	L	88.1	Confident	95	Very high	155 Å²	155	113.1 Å²	113.1	81%	0.812	61%	0.61	S	S	*	*	H	α-helix	trans	-87.2	-29.8	-179	-163.4	80.7	0	0	0	112.5	I47 I48	I47-L51 VanDerWaalsContact O-CB 3.32Å; I47-L51 WeakPolarHBondContact O-CB 3.43Å; I47-L51 PolarHBondContact O-N 2.94Å; I48-L51 PolarHBondContact O-N 3Å
52	L	82.8	Confident	94.7	Very high	202 Å²	202	116.9 Å²	116.9	100%	1.058	62%	0.622	S	S	*	*			trans	-80.6	0	176	-165.6	85.1	0	0	0	111	I48	I48-L52 WeakPolarHBondContact O-CB 3.36Å; I48-L52 PolarHBondContact O-N 3.28Å

Retrieved 52 of 52 residues in 134 ms (Link to these results)

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