A0A093I1D4_STRCA Loading...

Mitochondrial sodium/hydrogen exchanger 9B2

AlphaFold DB , UniProt , Accession A0A093I1D4, Species STRCA (Struthio camelus australis), Gene n/a, Length 544 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	35.4	Very low	27.9	Very low	239 Å²	239	150.2 Å²	150.2	100%	1.177	79%	0.788	S	S	*	*				0	102.9	0	-163	162	176.9	0	0	105.5
2	V	33.4	Very low	27.6	Very low	130 Å²	130	153 Å²	153	79%	0.788	79%	0.794	S	S	*	*			trans	36.1	113.2	168.2	-166	0	0	0	0	116.7
3	K	28.1	Very low	27.2	Very low	167 Å²	167	149.5 Å²	149.5	73%	0.726	79%	0.791	S	S	*	*			cis	61.5	99.9	19.8	-148.2	-165.8	-167	-105.9	0	117.7	D5	K3-D5 WeakPolarHBondContact CE-OD2 3.43Å; K3-D5 IonicContact NZ-OD2 3.11Å; K3-D5 PolarHBondContact NZ-OD2 3.31Å
4	E	29.8	Very low	27	Very low	180 Å²	180	151.4 Å²	151.4	84%	0.841	79%	0.793	S	S	*	*			trans	-173.7	129.4	138.8	-100.3	156.5	-168.1	0	0	106.3
5	D	28.4	Very low	26.7	Very low	100 Å²	100	152.8 Å²	152.8	54%	0.535	80%	0.8	S	S	.	*			cis	89.9	116.7	33.7	-82.7	-37.7	0	0	0	116.3	K3	K3-D5 WeakPolarHBondContact CE-OD2 3.43Å; K3-D5 IonicContact NZ-OD2 3.11Å; K3-D5 PolarHBondContact NZ-OD2 3.31Å
6	I	29.5	Very low	26.3	Very low	164 Å²	164	150.1 Å²	150.1	84%	0.841	80%	0.798	S	S	*	*			trans	73.6	136.7	141	-58.4	164.4	0	0	0	119.5
7	G	24.3	Very low	26.1	Very low	78 Å²	78	146.3 Å²	146.3	80%	0.804	79%	0.793	S	S	*	*			trans	172.2	85.2	167.3	0	0	0	0	0	112.6
8	N	24.7	Very low	25.8	Very low	144 Å²	144	144.9 Å²	144.9	77%	0.77	79%	0.794	S	S	*	*			trans	-99.5	178	176.6	-171.4	52.7	0	0	0	110.6
9	E	25.2	Very low	25.7	Very low	176 Å²	176	143.7 Å²	143.7	82%	0.822	79%	0.792	S	S	*	*			trans	105.3	150.9	172.7	-64.8	171.9	-174.8	0	0	114.6
10	N	23.5	Very low	25.6	Very low	117 Å²	117	144.5 Å²	144.5	63%	0.626	79%	0.789	S	S	*	*			cis	177.8	147.3	-37.1	-126.3	31.6	0	0	0	105
11	E	24.6	Very low	25.5	Very low	157 Å²	157	143.1 Å²	143.1	73%	0.734	78%	0.781	S	S	*	*			trans	69.9	149.3	144.8	-73.6	171.1	132.2	0	0	123.9
12	E	24.9	Very low	24.8	Very low	184 Å²	184	135.9 Å²	135.9	86%	0.86	77%	0.767	S	S	*	*			trans	66	153.3	157.8	-72.6	-178	177.5	0	0	120.2
13	S	22	Very low	24.3	Very low	108 Å²	108	136.2 Å²	136.2	76%	0.755	76%	0.762	S	S	*	*			cis	-163	178.2	-27.8	-164.6	0	0	0	0	109
14	E	23.8	Very low	24.1	Very low	175 Å²	175	134.5 Å²	134.5	82%	0.818	76%	0.76	S	S	*	*			trans	-70.9	147.2	-176.3	-55	174.2	110.2	0	0	114.9
15	L	22.4	Very low	24.4	Very low	173 Å²	173	131.4 Å²	131.4	91%	0.906	76%	0.755	S	S	*	*			trans	177.4	116.4	134.9	-115.7	76.3	0	0	0	107.9
16	S	21.1	Very low	24.1	Very low	109 Å²	109	133.7 Å²	133.7	76%	0.762	76%	0.764	S	S	*	*				90.1	111.6	65.2	-162.3	0	0	0	0	115.7
17	A	22.2	Very low	23.8	Very low	86 Å²	86	134.5 Å²	134.5	71%	0.711	76%	0.764	S	S	*	*			trans	59.1	115	144.3	0	0	0	0	0	123.3
18	C	21.3	Very low	23.7	Very low	122 Å²	122	138.3 Å²	138.3	82%	0.824	76%	0.761	S	S	*	*				-169.7	123.5	117.2	-91.2	0	0	0	0	108.2
19	V	23.9	Very low	23.4	Very low	122 Å²	122	141.1 Å²	141.1	74%	0.739	77%	0.767	S	S	*	*				69.5	121.1	73.3	174.3	0	0	0	0	109.9
20	E	23.5	Very low	23.2	Very low	159 Å²	159	136.8 Å²	136.8	74%	0.743	76%	0.755	S	S	*	*			cis	-158.7	150.8	31.8	-148	-178.3	126.3	0	0	116.8
21	N	22.9	Very low	23.1	Very low	115 Å²	115	141.2 Å²	141.2	62%	0.615	77%	0.769	S	S	*	*			trans	45.3	126.2	146.4	-74.4	-25.5	0	0	0	126.3
22	G	21.9	Very low	23	Very low	87 Å²	87	142.8 Å²	142.8	90%	0.897	78%	0.776	S	S	*	*			trans	-149.8	106	140.2	0	0	0	0	0	109.2
23	M	22	Very low	22.8	Very low	137 Å²	137	137.6 Å²	137.6	68%	0.675	77%	0.773	S	S	*	*			trans	-126.2	120.5	-146.7	-172.7	175.1	179.1	0	0	114.8
24	I	23.2	Very low	23.1	Very low	132 Å²	132	138.9 Å²	138.9	68%	0.677	78%	0.778	S	S	*	*			trans	67.4	174.9	141.4	-65.5	-178.7	0	0	0	115.1
25	P	36.2	Very low	23.1	Very low	114 Å²	114	136.9 Å²	136.9	74%	0.74	78%	0.778	S	S	*	*			cis	-114	-170.4	-7.8	8.5	18.9	0	0	0	114.1
26	M	22.5	Very low	23.1	Very low	149 Å²	149	135.7 Å²	135.7	73%	0.734	78%	0.778	S	S	*	*			cis	-171.7	147.7	-23.1	-107.6	-86.2	-165	0	0	108.6
27	H	23.3	Very low	23.1	Very low	181 Å²	181	137.5 Å²	137.5	84%	0.838	78%	0.779	S	S	*	*				-179	121	105.1	-121.6	-60	0	0	0	114.3
28	E	21.9	Very low	23.1	Very low	157 Å²	157	140.2 Å²	140.2	73%	0.734	79%	0.787	S	S	*	*			trans	-104.6	161.1	165.1	-172.2	-176.7	162.5	0	0	109.6
29	K	19.9	Very low	23.1	Very low	204 Å²	204	144.2 Å²	144.2	89%	0.887	79%	0.79	S	S	*	*			trans	-151	107.3	159.9	-148.6	172	-169.1	173.8	0	112.1
30	S	21.1	Very low	22.9	Very low	84 Å²	84	141.6 Å²	141.6	59%	0.587	79%	0.788	S	S	*	*			trans	-94.7	162.7	174.1	-178.9	0	0	0	0	112.1
31	K	20.1	Very low	22.9	Very low	211 Å²	211	141 Å²	141	92%	0.917	80%	0.795	S	S	*	*			trans	-158.6	130.3	156.6	-102.2	-165.8	177.3	-169.1	0	110.8
32	E	22.4	Very low	23.2	Very low	189 Å²	189	143.2 Å²	143.2	88%	0.883	81%	0.807	S	S	*	*			trans	-112.8	155.5	176.7	-64.9	-179.4	129.7	0	0	113.1
33	G	21.2	Very low	23.5	Very low	76 Å²	76	142.8 Å²	142.8	78%	0.784	80%	0.802	S	S	*	*			trans	93.9	155.7	140.3	0	0	0	0	0	118.6
34	P	27.2	Very low	23.7	Very low	135 Å²	135	142 Å²	142	88%	0.877	80%	0.801	S	S	*	*			cis	-129.3	-172.6	9.2	41.8	-24.9	0	0	0	116.1
35	T	24.1	Very low	24	Very low	132 Å²	132	141.7 Å²	141.7	81%	0.81	81%	0.805	S	S	*	*			trans	-99.5	146.8	-171.1	49.6	0	0	0	0	116.3
36	V	22.4	Very low	23.7	Very low	148 Å²	148	144.1 Å²	144.1	90%	0.897	81%	0.806	S	S	*	*			trans	-150.6	141	150.8	-179.2	0	0	0	0	110.8
37	D	21.9	Very low	23.8	Very low	148 Å²	148	141.1 Å²	141.1	79%	0.791	80%	0.797	S	S	*	*			trans	-78.8	142.4	175.3	-73.3	-70.2	0	0	0	114.7
38	T	22	Very low	24.1	Very low	143 Å²	143	139.8 Å²	139.8	88%	0.877	79%	0.791	S	S	*	*				-166.2	136.2	125.5	3.3	0	0	0	0	116.4
39	K	21.3	Very low	24.5	Very low	206 Å²	206	137.7 Å²	137.7	90%	0.896	78%	0.781	S	S	*	*			trans	-31.7	129.5	160.9	-168.9	-177.5	-166.1	177.6	0	117.2
40	G	20.4	Very low	25	Very low	67 Å²	67	132 Å²	132	69%	0.691	76%	0.764	S	S	*	*			trans	166.3	102.3	160.5	0	0	0	0	0	119.9
41	T	22.6	Very low	25.2	Very low	145 Å²	145	130.6 Å²	130.6	89%	0.89	76%	0.757	S	S	*	*			trans	68.6	142	140.2	-38.9	0	0	0	0	122
42	D	28.6	Very low	25.8	Very low	163 Å²	163	126.6 Å²	126.6	87%	0.872	75%	0.745	S	S	*	*			trans	-54	151.8	172.1	-70.7	-71.8	0	0	0	115
43	G	29.9	Very low	26.2	Very low	77 Å²	77	123.1 Å²	123.1	79%	0.794	73%	0.732	S	S	*	*			trans	131.9	52.3	146.3	0	0	0	0	0	119.1
44	N	25.6	Very low	26.5	Very low	121 Å²	121	124.4 Å²	124.4	65%	0.647	72%	0.721	S	S	*	*			trans	-154.6	90.5	157.6	-149.2	-8.6	0	0	0	114.1	T47	N44-T47 VanDerWaalsContact OD1-CB 3.3Å; N44-T47 WeakPolarHBondContact OD1-CB 3.19Å; N44-T47 PolarHBondContact OD1-OG1 3.35Å
45	V	29.9	Very low	26.4	Very low	126 Å²	126	124.9 Å²	124.9	76%	0.764	71%	0.711	S	S	*	*	S	Bend	trans	-128	-12.8	175.7	-176.8	0	0	0	0	112.9
46	Q	28.8	Very low	26.6	Very low	164 Å²	164	123.9 Å²	123.9	77%	0.766	71%	0.708	S	S	*	*	S	Bend	trans	-91.7	-15.4	-178.9	-69.5	-177.4	-68.5	0	0	114.1	T50	Q46-T50 PolarHBondContact O-N 3.19Å; Q46-T50 PolarHBondContact O-OG1 3.25Å
47	T	26.2	Very low	26.7	Very low	87 Å²	87	120.6 Å²	120.6	53%	0.534	70%	0.696	S	S	.	*	H	α-helix	trans	-76	-37.3	-174	-49.5	0	0	0	0	112.4	N44 T50 A51	N44-T47 VanDerWaalsContact OD1-CB 3.3Å; N44-T47 WeakPolarHBondContact OD1-CB 3.19Å; N44-T47 PolarHBondContact OD1-OG1 3.35Å; T47-T50 PolarHBondContact O-N 2.69Å; T47-A51 PolarHBondContact O-N 3.27Å
48	E	29	Very low	26.8	Very low	152 Å²	152	120.4 Å²	120.4	71%	0.71	69%	0.691	S	S	*	*	H	α-helix	trans	-70.5	-36.6	177.5	-76.8	-168.4	116.7	0	0	113.8	T50 A51 L52	E48-T50 PolarHBondContact O-N 2.66Å; E48-A51 PolarHBondContact O-N 3.38Å; E48-A51 VanDerWaalsContact O-N 3.16Å; E48-L52 WeakPolarHBondContact O-CG 3.23Å; E48-L52 PolarHBondContact O-N 3.49Å
49	E	30.3	Very low	26.8	Very low	114 Å²	114	121.8 Å²	121.8	53%	0.533	69%	0.687	S	S	.	*	H	α-helix	trans	-67.3	-28.2	178.4	-151.3	162	-125	0	0	111.1	L53 R385	E49-L53 PolarHBondContact O-N 2.73Å; E49-R385 IonicContact OE1-NH2 3.49Å; E49-R385 PolarHBondContact OE1-NH2 2.95Å
50	T	30.2	Very low	26.9	Very low	85 Å²	85	117.4 Å²	117.4	52%	0.521	68%	0.68	S	S	.	*	H	α-helix	trans	-75.1	-40.5	171.1	-47.4	0	0	0	0	111.8	Q46 T47 E48 L53 N54	Q46-T50 PolarHBondContact O-N 3.19Å; Q46-T50 PolarHBondContact O-OG1 3.25Å; T47-T50 PolarHBondContact O-N 2.69Å; E48-T50 PolarHBondContact O-N 2.66Å; T50-L53 PolarHBondContact O-N 3.21Å; T50-N54 PolarHBondContact O-N 3.09Å
51	A	25.7	Very low	27	Very low	54 Å²	54	123.3 Å²	123.3	45%	0.446	69%	0.69	S	S	.	*	H	α-helix	trans	-63.9	-40.9	176.4	0	0	0	0	0	112.8	T47 E48 L53 N54 H55	T47-A51 PolarHBondContact O-N 3.27Å; E48-A51 PolarHBondContact O-N 3.38Å; E48-A51 VanDerWaalsContact O-N 3.16Å; A51-L53 VanDerWaalsContact C-N 3.31Å; A51-L53 PolarHBondContact O-N 3.43Å; A51-N54 PolarHBondContact O-N 3.43Å; A51-H55 PolarHBondContact O-N 3.1Å
52	L	31.5	Very low	27.1	Very low	126 Å²	126	123.3 Å²	123.3	66%	0.66	68%	0.684	S	S	*	*	H	α-helix	trans	-66.9	-29.9	177.6	-72.8	171.8	0	0	0	113	E48 C56	E48-L52 WeakPolarHBondContact O-CG 3.23Å; E48-L52 PolarHBondContact O-N 3.49Å; L52-C56 PolarHBondContact O-N 3.31Å
53	L	31.4	Very low	27	Very low	117 Å²	117	121.1 Å²	121.1	61%	0.613	68%	0.678	S	S	*	*	H	α-helix	trans	-76.3	-35.5	171.8	-81.8	170.7	0	0	0	112.5	E49 T50 A51 H55 C56 A57	E49-L53 PolarHBondContact O-N 2.73Å; T50-L53 PolarHBondContact O-N 3.21Å; A51-L53 VanDerWaalsContact C-N 3.31Å; A51-L53 PolarHBondContact O-N 3.43Å; L53-H55 VanDerWaalsContact C-N 3.29Å; L53-H55 PolarHBondContact O-N 2.91Å; L53-C56 CarbonylContact O-C 3.52Å; L53-C56 PolarHBondContact O-N 2.65Å; L53-C56 VanDerWaalsContact O-N 3.13Å; L53-A57 WeakPolarHBondContact O-CB 3.32Å; L53-A57 PolarHBondContact O-N 3.49Å
54	N	26.3	Very low	27.1	Very low	102 Å²	102	126 Å²	126	55%	0.545	68%	0.684	S	S	.	*	H	α-helix	trans	-61.3	-39.1	170.8	-81.6	-13.8	0	0	0	111.8	T50 A51 C56 A57 Q58	T50-N54 PolarHBondContact O-N 3.09Å; A51-N54 PolarHBondContact O-N 3.43Å; N54-C56 PolarHBondContact O-N 3.13Å; N54-A57 PolarHBondContact O-N 3.48Å; N54-A57 VanDerWaalsContact O-N 3.13Å; N54-Q58 PolarHBondContact O-N 2.88Å
55	H	25.5	Very low	27.3	Very low	146 Å²	146	124.6 Å²	124.6	68%	0.676	69%	0.69	S	S	*	*	H	α-helix	trans	-68.8	-19.5	176.2	-133.6	-44.3	0	0	0	114	A51 L53	A51-H55 PolarHBondContact O-N 3.1Å; L53-H55 VanDerWaalsContact C-N 3.29Å; L53-H55 PolarHBondContact O-N 2.91Å
56	C	29	Very low	27.4	Very low	110 Å²	110	121.2 Å²	121.2	74%	0.743	68%	0.681	S	S	*	*	H	α-helix	trans	-94.3	-18	170.5	-94.9	0	0	0	0	113.6	L52 L53 N54	L52-C56 PolarHBondContact O-N 3.31Å; L53-C56 CarbonylContact O-C 3.52Å; L53-C56 PolarHBondContact O-N 2.65Å; L53-C56 VanDerWaalsContact O-N 3.13Å; N54-C56 PolarHBondContact O-N 3.13Å
57	A	25	Very low	27.6	Very low	79 Å²	79	119.6 Å²	119.6	65%	0.653	69%	0.685	S	S	*	*	H	α-helix	trans	-83.5	-23.6	175.2	0	0	0	0	0	112.2	L53 N54 Q59	L53-A57 WeakPolarHBondContact O-CB 3.32Å; L53-A57 PolarHBondContact O-N 3.49Å; N54-A57 PolarHBondContact O-N 3.48Å; N54-A57 VanDerWaalsContact O-N 3.13Å; A57-Q59 PolarHBondContact O-N 3.39Å; A57-Q59 VanDerWaalsContact O-N 3.17Å
58	Q	22.6	Very low	27.8	Very low	145 Å²	145	121.4 Å²	121.4	68%	0.678	70%	0.7	S	S	*	*			trans	-78.5	91.1	167.7	-72.5	176.1	-22	0	0	110.5	N54	N54-Q58 PolarHBondContact O-N 2.88Å
59	Q	23.4	Very low	28.1	Very low	172 Å²	172	119.7 Å²	119.7	80%	0.804	70%	0.701	S	S	*	*			trans	-55.4	149.3	144.3	-81.3	-177	-110.2	0	0	108.6	A57 Q61	A57-Q59 PolarHBondContact O-N 3.39Å; A57-Q59 VanDerWaalsContact O-N 3.17Å; Q59-Q61 PolarHBondContact O-N 3.16Å
60	P	23.5	Very low	28.6	Very low	114 Å²	114	119.6 Å²	119.6	74%	0.74	71%	0.712	S	S	*	*			trans	-52.4	132.7	171.1	-22.5	32.7	0	0	0	109.6	D62	P60-D62 PolarHBondContact O-N 3Å; P60-D62 VanDerWaalsContact O-N 3.11Å
61	Q	21.7	Very low	29.1	Very low	191 Å²	191	119 Å²	119	89%	0.893	72%	0.716	S	S	*	*			trans	-64.1	112.9	166.3	-75.1	-178.4	-19.2	0	0	107.5	Q59	Q59-Q61 PolarHBondContact O-N 3.16Å
62	D	25.1	Very low	30	Very low	145 Å²	145	118.4 Å²	118.4	78%	0.775	72%	0.715	S	S	*	*			trans	-57.2	131.7	163	-74.2	-49.2	0	0	0	107.8	P60 I64	P60-D62 PolarHBondContact O-N 3Å; P60-D62 VanDerWaalsContact O-N 3.11Å; D62-I64 PolarHBondContact O-N 3.35Å
63	P	26.9	Very low	31	Very low	116 Å²	116	117.1 Å²	117.1	75%	0.753	71%	0.713	S	S	*	*			trans	-60.7	137.4	177.1	25.7	-33.4	0	0	0	109.3	A65	P63-A65 PolarHBondContact O-N 3.27Å
64	I	30.7	Very low	31.8	Very low	179 Å²	179	116.9 Å²	116.9	92%	0.918	71%	0.712	S	S	*	*			trans	-54	100.3	-172.6	-59.1	172	0	0	0	110.3	D62	D62-I64 PolarHBondContact O-N 3.35Å
65	A	29.4	Very low	32.9	Very low	93 Å²	93	122.3 Å²	122.3	77%	0.769	72%	0.724	S	S	*	*			trans	-82.7	122.4	175.5	0	0	0	0	0	109.4	P63	P63-A65 PolarHBondContact O-N 3.27Å
66	G	32.1	Very low	34.1	Very low	55 Å²	55	121.6 Å²	121.6	57%	0.567	72%	0.721	S	S	*	*			trans	-62.5	-179.8	171.5	0	0	0	0	0	113.3	S68	G66-S68 PolarHBondContact O-N 3.22Å
67	P	33.5	Very low	35.2	Very low	130 Å²	130	120.7 Å²	120.7	84%	0.844	71%	0.708	S	S	*	*	S	Bend	trans	-54.2	131.4	-166.3	20.8	-33	0	0	0	113.3	T69	P67-T69 PolarHBondContact O-N 3.29Å
68	S	31.1	Very low	36.6	Very low	124 Å²	124	124.9 Å²	124.9	87%	0.867	71%	0.712	S	S	*	*			trans	-67.9	114.7	-167.9	43.7	0	0	0	0	113	G66	G66-S68 PolarHBondContact O-N 3.22Å
69	T	34.5	Very low	38.3	Very low	117 Å²	117	119.9 Å²	119.9	72%	0.718	70%	0.696	S	S	*	*			trans	-94.6	120.1	164.4	-50.9	0	0	0	0	109	P67 A71 G72	P67-T69 PolarHBondContact O-N 3.29Å; T69-A71 PolarHBondContact O-N 3.14Å; T69-G72 PolarHBondContact O-N 2.9Å
70	S	41	Very low	39.9	Very low	111 Å²	111	117.7 Å²	117.7	78%	0.776	70%	0.698	S	S	*	*	T	Hydrogen-bonded Turn	trans	-51.9	-20.2	-170.5	-167	0	0	0	0	115.9	G72	S70-G72 VanDerWaalsContact C-N 3.32Å; S70-G72 PolarHBondContact O-N 3.16Å
71	A	40.2	Very low	41.9	Very low	73 Å²	73	117 Å²	117	60%	0.603	69%	0.693	S	S	*	*	H	α-helix	trans	-69.5	-18.5	-179.8	0	0	0	0	0	115.4	T69	T69-A71 PolarHBondContact O-N 3.14Å
72	G	44.9	Very low	44	Very low	41 Å²	41	110.6 Å²	110.6	42%	0.423	67%	0.668	S	S	.	*	H	α-helix	trans	-67.8	-48.5	-175.8	0	0	0	0	0	114	T69 S70 L74 R75 Q76	T69-G72 PolarHBondContact O-N 2.9Å; S70-G72 VanDerWaalsContact C-N 3.32Å; S70-G72 PolarHBondContact O-N 3.16Å; G72-L74 VanDerWaalsContact C-N 3.3Å; G72-L74 PolarHBondContact O-N 2.87Å; G72-R75 PolarHBondContact O-N 3.48Å; G72-Q76 PolarHBondContact O-N 3.34Å
73	T	52.2	Low	46.3	Very low	99 Å²	99	110.4 Å²	110.4	61%	0.607	66%	0.663	S	S	*	*	H	α-helix	trans	-61.5	-37.2	-174.3	-43.3	0	0	0	0	112.6	R75 Q76 I77	T73-R75 VanDerWaalsContact C-N 3.32Å; T73-R75 PolarHBondContact O-N 3.14Å; T73-Q76 PolarHBondContact O-N 3.29Å; T73-I77 WeakPolarHBondContact O-CG1 3.3Å; T73-I77 PolarHBondContact O-N 2.95Å
74	L	48.3	Very low	48.9	Very low	113 Å²	113	107.6 Å²	107.6	59%	0.592	66%	0.655	S	S	*	*	H	α-helix	trans	-71	-29.5	-178.1	-130.8	149.3	0	0	0	111.9	G72 F78	G72-L74 VanDerWaalsContact C-N 3.3Å; G72-L74 PolarHBondContact O-N 2.87Å; L74-F78 HydrophobicContact CD2-CD2 4.4Å; L74-F78 HydrophobicContact CD2-CE2 4.17Å
75	R	50	Low	51.2	Low	215 Å²	215	105.3 Å²	105.3	81%	0.811	64%	0.644	S	S	*	*	H	α-helix	trans	-75.3	-30.7	177.8	-131	177.8	-174	-175.1	1.3	113	G72 T73 F78 A79	G72-R75 PolarHBondContact O-N 3.48Å; T73-R75 VanDerWaalsContact C-N 3.32Å; T73-R75 PolarHBondContact O-N 3.14Å; R75-F78 PolarHBondContact O-N 3.46Å; R75-A79 PolarHBondContact O-N 2.9Å
76	Q	50.6	Low	53.6	Low	132 Å²	132	105 Å²	105	62%	0.617	63%	0.629	S	S	*	*	H	α-helix	trans	-70.8	-30.3	173.8	-83.8	177.7	-36.7	0	0	113.2	G72 T73 F78 A79	G72-Q76 PolarHBondContact O-N 3.34Å; T73-Q76 PolarHBondContact O-N 3.29Å; Q76-F78 PolarHBondContact O-N 3.45Å; Q76-A79 PolarHBondContact O-N 3.44Å
77	I	51.3	Low	56.1	Low	91 Å²	91	103.5 Å²	103.5	47%	0.467	61%	0.611	S	S	.	*	H	α-helix	trans	-65	-30.3	176.4	-66.7	168.1	0	0	0	111.7	T73	T73-I77 WeakPolarHBondContact O-CG1 3.3Å; T73-I77 PolarHBondContact O-N 2.95Å
78	F	55.2	Low	58.4	Low	167 Å²	167	106.1 Å²	106.1	73%	0.732	60%	0.604	S	S	*	*	T	Hydrogen-bonded Turn	trans	-98.6	8.9	179.2	-77	-81.2	0	0	0	114.4	L74 R75 Q76	L74-F78 HydrophobicContact CD2-CD2 4.4Å; L74-F78 HydrophobicContact CD2-CE2 4.17Å; R75-F78 PolarHBondContact O-N 3.46Å; Q76-F78 PolarHBondContact O-N 3.45Å
79	A	58.8	Low	60.9	Low	40 Å²	40	104.6 Å²	104.6	33%	0.331	59%	0.585	S	S	.	*			trans	-68.4	139.3	171.8	0	0	0	0	0	110.8	R75 Q76 P81 P82	R75-A79 PolarHBondContact O-N 2.9Å; Q76-A79 PolarHBondContact O-N 3.44Å; A79-P81 CarbonylContact C-O 3.45Å; A79-P81 CarbonylContact O-C 3.49Å; A79-P82 VanDerWaalsContact O-CA 3.25Å; A79-P82 WeakPolarHBondContact O-CA 3.44Å; A79-P82 VanDerWaalsContact O-N 3.13Å
80	C	56.1	Low	63.4	Low	126 Å²	126	102.5 Å²	102.5	85%	0.851	57%	0.572	S	S	*	*	S	Bend	trans	-111.1	123.4	169.8	-75.9	0	0	0	0	109.2
81	P	65.4	Low	65.6	Low	99 Å²	99	101 Å²	101	64%	0.643	56%	0.558	S	S	*	*	S	Bend	cis	-67.2	151.7	-4.7	30.3	-35.9	0	0	0	112.2	A79 Q83	A79-P81 CarbonylContact C-O 3.45Å; A79-P81 CarbonylContact O-C 3.49Å; P81-Q83 PolarHBondContact O-N 3.33Å
82	P	67.6	Low	67.7	Low	57 Å²	57	100.4 Å²	100.4	37%	0.37	55%	0.545	S	S	.	.			trans	-60.4	138.3	175.7	25.9	-34.1	0	0	0	109.8	A79 L86 A87	A79-P82 VanDerWaalsContact O-CA 3.25Å; A79-P82 WeakPolarHBondContact O-CA 3.44Å; A79-P82 VanDerWaalsContact O-N 3.13Å; P82-L86 HydrophobicContact CB-CD2 4.37Å; P82-A87 HydrophobicContact CB-CB 4.23Å; P82-A87 HydrophobicContact CG-CB 4.23Å; P82-A87 VanDerWaalsContact O-CB 3.24Å; P82-A87 WeakPolarHBondContact O-CB 3.49Å
83	Q	73.3	Confident	69.7	Low	140 Å²	140	102.4 Å²	102.4	65%	0.654	55%	0.549	S	S	*	.			trans	-118.1	155.8	177.6	-66	-174.9	-7.5	0	0	110.6	P81	P81-Q83 PolarHBondContact O-N 3.33Å
84	G	81.5	Confident	71.5	Confident	58 Å²	58	101.9 Å²	101.9	60%	0.598	55%	0.545	S	S	*	.	S	Bend	trans	76.7	-142.1	179.4	0	0	0	0	0	114.8	L86 A87 R88	G84-L86 PolarHBondContact O-N 2.97Å; G84-A87 PolarHBondContact O-N 3.35Å; G84-R88 PolarHBondContact O-N 3.3Å
85	L	77.9	Confident	73.5	Confident	131 Å²	131	100.8 Å²	100.8	69%	0.686	54%	0.539	S	S	*	.	H	α-helix	trans	-63.3	-41.8	-165.3	-175.4	65.1	0	0	0	113.5	R88 I89	L85-R88 PolarHBondContact O-N 3.44Å; L85-I89 HydrophobicContact CD1-CD1 4.35Å; L85-I89 HydrophobicContact CG-CD1 3.98Å; L85-I89 WeakPolarHBondContact O-CG1 3.4Å; L85-I89 PolarHBondContact O-N 3.24Å
86	L	79.7	Confident	75.2	Confident	86 Å²	86	93.2 Å²	93.2	45%	0.45	52%	0.517	S	S	.	.	H	α-helix	trans	-60.2	-49.4	-178.1	-176.8	68.1	0	0	0	111.1	P82 G84 R88 I89 V90	P82-L86 HydrophobicContact CB-CD2 4.37Å; G84-L86 PolarHBondContact O-N 2.97Å; L86-R88 VanDerWaalsContact C-N 3.31Å; L86-R88 PolarHBondContact O-N 3.33Å; L86-I89 PolarHBondContact O-N 2.95Å; L86-I89 VanDerWaalsContact O-N 3.16Å; L86-V90 WeakPolarHBondContact O-CG2 3.38Å; L86-V90 PolarHBondContact O-N 3.28Å
87	A	85	Confident	77.1	Confident	23 Å²	23	90.9 Å²	90.9	19%	0.19	51%	0.511	C	S	.	.	H	α-helix	trans	-57.7	-45.2	176.9	0	0	0	0	0	111.4	P82 G84 I89 V90 T91	P82-A87 HydrophobicContact CB-CB 4.23Å; P82-A87 HydrophobicContact CG-CB 4.23Å; P82-A87 VanDerWaalsContact O-CB 3.24Å; P82-A87 WeakPolarHBondContact O-CB 3.49Å; G84-A87 PolarHBondContact O-N 3.35Å; A87-I89 VanDerWaalsContact C-N 3.33Å; A87-I89 PolarHBondContact O-N 3.42Å; A87-V90 PolarHBondContact O-N 2.91Å; A87-T91 WeakPolarHBondContact O-CB 3.26Å; A87-T91 PolarHBondContact O-N 3.16Å; A87-T91 PolarHBondContact O-OG1 2.89Å
88	R	81.7	Confident	79	Confident	186 Å²	186	91.8 Å²	91.8	70%	0.702	52%	0.516	S	S	*	.	H	α-helix	trans	-61.5	-39.2	177.6	-165.8	177.4	-171.7	-174.2	3.9	112.3	G84 L85 L86 N92	G84-R88 PolarHBondContact O-N 3.3Å; L85-R88 PolarHBondContact O-N 3.44Å; L86-R88 VanDerWaalsContact C-N 3.31Å; L86-R88 PolarHBondContact O-N 3.33Å; R88-N92 PolarHBondContact O-N 3.41Å; R88-N92 VanDerWaalsContact O-N 3.15Å; R88-N92 PolarHBondContact O-ND2 3Å
89	I	83.6	Confident	80.6	Confident	91 Å²	91	86.6 Å²	86.6	47%	0.467	50%	0.499	S	S	.	.	H	α-helix	trans	-65.6	-50.8	175.4	-68.4	168.3	0	0	0	110	L85 L86 A87 T91 N92 V93	L85-I89 HydrophobicContact CD1-CD1 4.35Å; L85-I89 HydrophobicContact CG-CD1 3.98Å; L85-I89 WeakPolarHBondContact O-CG1 3.4Å; L85-I89 PolarHBondContact O-N 3.24Å; L86-I89 PolarHBondContact O-N 2.95Å; L86-I89 VanDerWaalsContact O-N 3.16Å; A87-I89 VanDerWaalsContact C-N 3.33Å; A87-I89 PolarHBondContact O-N 3.42Å; I89-T91 PolarHBondContact O-N 3.33Å; I89-N92 PolarHBondContact O-N 3.49Å; I89-N92 VanDerWaalsContact O-N 3.15Å; I89-V93 HydrophobicContact CG2-CG2 4.4Å; I89-V93 WeakPolarHBondContact O-CG2 3.47Å; I89-V93 PolarHBondContact O-N 3.45Å
90	V	86.9	Confident	82	Confident	73 Å²	73	89 Å²	89	44%	0.442	50%	0.499	S	S	.	.	H	α-helix	trans	-56.4	-48.5	178.8	173	0	0	0	0	111.2	L86 A87 N92 V93 V94	L86-V90 WeakPolarHBondContact O-CG2 3.38Å; L86-V90 PolarHBondContact O-N 3.28Å; A87-V90 PolarHBondContact O-N 2.91Å; V90-N92 PolarHBondContact O-N 3.39Å; V90-V93 PolarHBondContact O-N 2.91Å; V90-V94 HydrophobicContact CG1-CG2 4.24Å; V90-V94 WeakPolarHBondContact O-CB 3.41Å; V90-V94 WeakPolarHBondContact O-CG2 3.25Å; V90-V94 PolarHBondContact O-N 3.44Å
91	T	87.5	Confident	83.5	Confident	80 Å²	80	84.7 Å²	84.7	49%	0.491	47%	0.472	S	S	.	.	H	α-helix	trans	-59.2	-42.9	177	-56.8	0	0	0	0	112.3	A87 I89 V94 I95	A87-T91 WeakPolarHBondContact O-CB 3.26Å; A87-T91 PolarHBondContact O-N 3.16Å; A87-T91 PolarHBondContact O-OG1 2.89Å; I89-T91 PolarHBondContact O-N 3.33Å; T91-V94 PolarHBondContact O-N 2.87Å; T91-I95 HydrophobicContact CG2-CD1 3.94Å; T91-I95 WeakPolarHBondContact O-CD1 3.49Å; T91-I95 VanDerWaalsContact O-CG1 3.25Å; T91-I95 WeakPolarHBondContact O-CG1 3.37Å; T91-I95 PolarHBondContact O-N 3Å
92	N	85.1	Confident	84.7	Confident	61 Å²	61	83.4 Å²	83.4	33%	0.326	46%	0.463	S	S	.	.	H	α-helix	trans	-63.4	-43.8	176.2	-78.9	-75.8	0	0	0	111.6	R88 I89 V90 I95 V96 K132	R88-N92 PolarHBondContact O-N 3.41Å; R88-N92 VanDerWaalsContact O-N 3.15Å; R88-N92 PolarHBondContact O-ND2 3Å; I89-N92 PolarHBondContact O-N 3.49Å; I89-N92 VanDerWaalsContact O-N 3.15Å; V90-N92 PolarHBondContact O-N 3.39Å; N92-I95 PolarHBondContact O-N 3.23Å; N92-V96 WeakPolarHBondContact O-CG2 3.41Å; N92-V96 PolarHBondContact O-N 3.33Å; N92-K132 PolarHBondContact OD1-NZ 2.88Å
93	V	86.4	Confident	85.6	Confident	82 Å²	82	82.6 Å²	82.6	50%	0.497	46%	0.456	S	S	.	.	H	α-helix	trans	-64	-44.6	178.7	173.1	0	0	0	0	111	I89 V90 I95 V96 V97	I89-V93 HydrophobicContact CG2-CG2 4.4Å; I89-V93 WeakPolarHBondContact O-CG2 3.47Å; I89-V93 PolarHBondContact O-N 3.45Å; V90-V93 PolarHBondContact O-N 2.91Å; V93-I95 VanDerWaalsContact C-N 3.32Å; V93-I95 PolarHBondContact O-N 3.32Å; V93-V96 PolarHBondContact O-N 3.11Å; V93-V97 HydrophobicContact CG1-CG2 4.33Å; V93-V97 WeakPolarHBondContact O-CG2 3.4Å; V93-V97 PolarHBondContact O-N 3.45Å
94	V	89.7	Confident	86.4	Confident	88 Å²	88	81.6 Å²	81.6	53%	0.533	45%	0.447	S	S	.	.	H	α-helix	trans	-61.1	-40.1	176.7	171.5	0	0	0	0	111.4	V90 T91 V97 L98	V90-V94 HydrophobicContact CG1-CG2 4.24Å; V90-V94 WeakPolarHBondContact O-CB 3.41Å; V90-V94 WeakPolarHBondContact O-CG2 3.25Å; V90-V94 PolarHBondContact O-N 3.44Å; T91-V94 PolarHBondContact O-N 2.87Å; V94-V97 PolarHBondContact O-N 2.86Å; V94-L98 WeakPolarHBondContact O-CB 3.48Å; V94-L98 PolarHBondContact O-N 3.25Å
95	I	89.1	Confident	86.8	Confident	90 Å²	90	83.2 Å²	83.2	46%	0.462	45%	0.449	S	S	.	.	H	α-helix	trans	-62.1	-45.3	174.4	-70.8	163.9	0	0	0	111.4	T91 N92 V93 L98 V99	T91-I95 HydrophobicContact CG2-CD1 3.94Å; T91-I95 WeakPolarHBondContact O-CD1 3.49Å; T91-I95 VanDerWaalsContact O-CG1 3.25Å; T91-I95 WeakPolarHBondContact O-CG1 3.37Å; T91-I95 PolarHBondContact O-N 3Å; N92-I95 PolarHBondContact O-N 3.23Å; V93-I95 VanDerWaalsContact C-N 3.32Å; V93-I95 PolarHBondContact O-N 3.32Å; I95-L98 PolarHBondContact O-N 3.18Å; I95-V99 WeakPolarHBondContact O-CG2 3.44Å; I95-V99 PolarHBondContact O-N 3.36Å
96	V	87.4	Confident	87.3	Confident	56 Å²	56	83.1 Å²	83.1	34%	0.339	45%	0.448	S	S	.	.	H	α-helix	trans	-60.5	-48.5	177.9	173	0	0	0	0	110.8	N92 V93 V99 W100 F125	N92-V96 WeakPolarHBondContact O-CG2 3.41Å; N92-V96 PolarHBondContact O-N 3.33Å; V93-V96 PolarHBondContact O-N 3.11Å; V96-V99 PolarHBondContact O-N 3.15Å; V96-W100 WeakPolarHBondContact O-CB 3.39Å; V96-W100 PolarHBondContact O-N 3.26Å; V96-F125 HydrophobicContact CB-CE1 4.27Å; V96-F125 HydrophobicContact CB-CZ 4.36Å; V96-F125 HydrophobicContact CG1-CD1 4.26Å; V96-F125 HydrophobicContact CG1-CD2 3.94Å; V96-F125 HydrophobicContact CG1-CE1 4.26Å; V96-F125 HydrophobicContact CG1-CE2 3.94Å; V96-F125 HydrophobicContact CG1-CG 4.12Å; V96-F125 HydrophobicContact CG1-CZ 4.09Å; V96-F125 HydrophobicContact CG2-CD1 3.72Å; V96-F125 HydrophobicContact CG2-CE1 3.74Å; V96-F125 HydrophobicContact CG2-CG 4.3Å; V96-F125 HydrophobicContact CG2-CZ 4.32Å
97	V	88.9	Confident	87.6	Confident	84 Å²	84	81.2 Å²	81.2	51%	0.509	44%	0.44	S	S	.	.	H	α-helix	trans	-63.8	-41.7	179.2	172.8	0	0	0	0	111.3	V93 V94 W100 A101	V93-V97 HydrophobicContact CG1-CG2 4.33Å; V93-V97 WeakPolarHBondContact O-CG2 3.4Å; V93-V97 PolarHBondContact O-N 3.45Å; V94-V97 PolarHBondContact O-N 2.86Å; V97-W100 PolarHBondContact O-N 2.98Å; V97-A101 WeakPolarHBondContact O-CB 3.43Å; V97-A101 PolarHBondContact O-N 3.32Å
98	L	91.6	Very high	87.7	Confident	109 Å²	109	81.6 Å²	81.6	57%	0.571	45%	0.446	S	S	*	.	H	α-helix	trans	-63.5	-47.4	178.1	-177.9	66.8	0	0	0	111.7	V94 I95 A101 V102	V94-L98 WeakPolarHBondContact O-CB 3.48Å; V94-L98 PolarHBondContact O-N 3.25Å; I95-L98 PolarHBondContact O-N 3.18Å; L98-A101 PolarHBondContact O-N 3.48Å; L98-V102 HydrophobicContact CD1-CG2 4.38Å; L98-V102 WeakPolarHBondContact O-CB 3.42Å; L98-V102 VanDerWaalsContact O-CG2 3.3Å; L98-V102 WeakPolarHBondContact O-CG2 3.4Å; L98-V102 PolarHBondContact O-N 2.98Å
99	V	88.8	Confident	87.6	Confident	59 Å²	59	77.9 Å²	77.9	36%	0.358	44%	0.444	S	S	.	.	H	α-helix	trans	-61.2	-46.8	177.3	170.6	0	0	0	0	110.5	I95 V96 A101 V102 V103 L121 F125	I95-V99 WeakPolarHBondContact O-CG2 3.44Å; I95-V99 PolarHBondContact O-N 3.36Å; V96-V99 PolarHBondContact O-N 3.15Å; V99-A101 PolarHBondContact O-N 2.9Å; V99-V102 PolarHBondContact O-N 3.19Å; V99-V103 WeakPolarHBondContact O-CG2 3.26Å; V99-V103 PolarHBondContact O-N 2.87Å; V99-V103 VanDerWaalsContact O-N 3.1Å; V99-L121 HydrophobicContact CG1-CD2 4.22Å; V99-F125 HydrophobicContact CB-CZ 4.11Å; V99-F125 HydrophobicContact CG1-CZ 3.96Å
100	W	88.3	Confident	87.5	Confident	90 Å²	90	77.8 Å²	77.8	34%	0.341	44%	0.442	S	S	.	.	H	α-helix	trans	-61.8	-44.8	177.2	178.2	81.7	0	0	0	112.2	V96 V97 V102 V103 W104 C111	V96-W100 WeakPolarHBondContact O-CB 3.39Å; V96-W100 PolarHBondContact O-N 3.26Å; V97-W100 PolarHBondContact O-N 2.98Å; W100-V102 PolarHBondContact O-N 2.73Å; W100-V103 PolarHBondContact O-N 2.9Å; W100-W104 HydrophobicContact CH2-CD2 4.31Å; W100-W104 HydrophobicContact CH2-CG 4.22Å; W100-W104 HydrophobicContact CZ2-CB 4.42Å; W100-W104 HydrophobicContact CZ2-CG 4.24Å; W100-W104 VanDerWaalsContact O-CB 3.22Å; W100-W104 WeakPolarHBondContact O-CB 3.28Å; W100-W104 PolarHBondContact O-N 2.81Å; W100-C111 PolarHBondContact NE1-O 3.38Å
101	A	87.8	Confident	87.3	Confident	35 Å²	35	74.3 Å²	74.3	29%	0.289	42%	0.421	S	S	.	.	H	α-helix	trans	-64.5	-36.9	179.8	0	0	0	0	0	112.8	V97 L98 V99 S105	V97-A101 WeakPolarHBondContact O-CB 3.43Å; V97-A101 PolarHBondContact O-N 3.32Å; L98-A101 PolarHBondContact O-N 3.48Å; V99-A101 PolarHBondContact O-N 2.9Å; A101-S105 WeakPolarHBondContact O-CB 3.33Å; A101-S105 PolarHBondContact O-N 2.94Å; A101-S105 PolarHBondContact O-OG 3.5Å
102	V	90.4	Very high	87.1	Confident	73 Å²	73	74.3 Å²	74.3	44%	0.442	42%	0.417	S	S	.	.	H	α-helix	trans	-67.8	-44.2	175.4	169.1	0	0	0	0	111.6	L98 V99 W100 S105 I106	L98-V102 HydrophobicContact CD1-CG2 4.38Å; L98-V102 WeakPolarHBondContact O-CB 3.42Å; L98-V102 VanDerWaalsContact O-CG2 3.3Å; L98-V102 WeakPolarHBondContact O-CG2 3.4Å; L98-V102 PolarHBondContact O-N 2.98Å; V99-V102 PolarHBondContact O-N 3.19Å; W100-V102 PolarHBondContact O-N 2.73Å; V102-S105 PolarHBondContact O-N 2.82Å; V102-S105 PolarHBondContact O-OG 2.98Å; V102-I106 HydrophobicContact CG1-CD1 4.24Å; V102-I106 WeakPolarHBondContact O-CD1 3.45Å; V102-I106 WeakPolarHBondContact O-CG1 3.33Å; V102-I106 PolarHBondContact O-N 3.41Å
103	V	87.5	Confident	87	Confident	39 Å²	39	75.8 Å²	75.8	24%	0.236	43%	0.43	C	S	.	.	H	α-helix	trans	-68.6	-42.6	177.4	-171.3	0	0	0	0	110	V99 W100 S105 I106 T107 C111 L117 L121	V99-V103 WeakPolarHBondContact O-CG2 3.26Å; V99-V103 PolarHBondContact O-N 2.87Å; V99-V103 VanDerWaalsContact O-N 3.1Å; W100-V103 PolarHBondContact O-N 2.9Å; V103-S105 VanDerWaalsContact C-N 3.33Å; V103-S105 PolarHBondContact O-N 3.34Å; V103-I106 PolarHBondContact O-N 3.45Å; V103-I106 VanDerWaalsContact O-N 3.08Å; V103-T107 PolarHBondContact O-N 3.45Å; V103-T107 PolarHBondContact O-OG1 2.84Å; V103-C111 WeakPolarHBondContact CG1-SG 3.35Å; V103-L117 HydrophobicContact CG1-CD1 4.19Å; V103-L121 HydrophobicContact CB-CD1 4.06Å; V103-L121 HydrophobicContact CG1-CD1 4.28Å; V103-L121 HydrophobicContact CG2-CD1 4.16Å
104	W	88.8	Confident	86.7	Confident	120 Å²	120	73.5 Å²	73.5	46%	0.455	42%	0.423	S	S	.	.	H	α-helix	trans	-59	-39.3	176.1	176.9	69.7	0	0	0	113.1	W100 I106 G108 C111	W100-W104 HydrophobicContact CH2-CD2 4.31Å; W100-W104 HydrophobicContact CH2-CG 4.22Å; W100-W104 HydrophobicContact CZ2-CB 4.42Å; W100-W104 HydrophobicContact CZ2-CG 4.24Å; W100-W104 VanDerWaalsContact O-CB 3.22Å; W100-W104 WeakPolarHBondContact O-CB 3.28Å; W100-W104 PolarHBondContact O-N 2.81Å; W104-I106 PolarHBondContact O-N 2.88Å; W104-G108 VanDerWaalsContact CD1-O 3.32Å; W104-G108 WeakPolarHBondContact O-CA 3.4Å; W104-G108 PolarHBondContact O-N 3.29Å; W104-C111 HydrophobicContact CB-CB 3.87Å; W104-C111 HydrophobicContact CG-CB 4.31Å
105	S	89.8	Confident	86.6	Confident	92 Å²	92	69.8 Å²	69.8	64%	0.643	40%	0.402	S	S	*	.	H	α-helix	trans	-68.1	-22.2	177.4	70.9	0	0	0	0	113.8	A101 V102 V103	A101-S105 WeakPolarHBondContact O-CB 3.33Å; A101-S105 PolarHBondContact O-N 2.94Å; A101-S105 PolarHBondContact O-OG 3.5Å; V102-S105 PolarHBondContact O-N 2.82Å; V102-S105 PolarHBondContact O-OG 2.98Å; V103-S105 VanDerWaalsContact C-N 3.33Å; V103-S105 PolarHBondContact O-N 3.34Å
106	I	90	Very high	86.6	Confident	129 Å²	129	66.5 Å²	66.5	66%	0.662	39%	0.386	S	S	*	.	H	α-helix	trans	-89	-44.2	177	-61.4	165.1	0	0	0	111.1	V102 V103 W104	V102-I106 HydrophobicContact CG1-CD1 4.24Å; V102-I106 WeakPolarHBondContact O-CD1 3.45Å; V102-I106 WeakPolarHBondContact O-CG1 3.33Å; V102-I106 PolarHBondContact O-N 3.41Å; V103-I106 PolarHBondContact O-N 3.45Å; V103-I106 VanDerWaalsContact O-N 3.08Å; W104-I106 PolarHBondContact O-N 2.88Å
107	T	85.9	Confident	86.6	Confident	46 Å²	46	65.7 Å²	65.7	28%	0.282	38%	0.379	S	S	.	.	H	α-helix	trans	-112.1	-2.2	-167.3	62.4	0	0	0	0	115.1	V103 T109 E110 C111 L117	V103-T107 PolarHBondContact O-N 3.45Å; V103-T107 PolarHBondContact O-OG1 2.84Å; T107-T109 PolarHBondContact O-N 3.4Å; T107-E110 PolarHBondContact O-N 3.27Å; T107-C111 PolarHBondContact OG1-SG 3.42Å; T107-C111 VanDerWaalsContact OG1-SG 3.34Å; T107-L117 HydrophobicContact CG2-CD1 3.59Å; T107-L117 WeakPolarHBondContact OG1-CD1 3.28Å
108	G	85.6	Confident	86.6	Confident	31 Å²	31	63.3 Å²	63.3	32%	0.32	36%	0.362	S	S	.	.	G	3₁₀ helix	trans	53.8	-106.2	172.2	0	0	0	0	0	113.6	W104 E110 C111	W104-G108 VanDerWaalsContact CD1-O 3.32Å; W104-G108 WeakPolarHBondContact O-CA 3.4Å; W104-G108 PolarHBondContact O-N 3.29Å; G108-E110 VanDerWaalsContact C-N 3.34Å; G108-E110 PolarHBondContact O-N 3.1Å; G108-C111 PolarHBondContact O-N 3.48Å
109	T	80.4	Confident	86.5	Confident	107 Å²	107	58.1 Å²	58.1	66%	0.656	34%	0.335	S	S	*	.	G	3₁₀ helix	trans	-65.6	-29	-174.4	48.8	0	0	0	0	114.3	T107 C111 L112	T107-T109 PolarHBondContact O-N 3.4Å; T109-C111 PolarHBondContact O-N 3.24Å; T109-C111 VanDerWaalsContact O-N 3.17Å; T109-L112 HydrophobicContact CG2-CD1 4.42Å; T109-L112 WeakPolarHBondContact O-CB 2.87Å; T109-L112 PolarHBondContact O-N 2.91Å; T109-L112 VanDerWaalsContact O-N 3.11Å
110	E	81.9	Confident	86.7	Confident	90 Å²	90	56 Å²	56	42%	0.421	32%	0.321	S	S	.	.	G	3₁₀ helix	trans	-66.8	-15.1	178.3	-71.9	-63.4	143.3	0	0	113.8	T107 G108 G115 N116 L117 F118	T107-E110 PolarHBondContact O-N 3.27Å; G108-E110 VanDerWaalsContact C-N 3.34Å; G108-E110 PolarHBondContact O-N 3.1Å; E110-G115 CarbonylContact O-C 3.44Å; E110-G115 WeakPolarHBondContact O-CA 3.29Å; E110-N116 PolarHBondContact OE2-N 3.31Å; E110-L117 HydrophobicContact CB-CB 4.44Å; E110-L117 HydrophobicContact CB-CD1 3.98Å; E110-L117 HydrophobicContact CB-CG 4.3Å; E110-L117 WeakPolarHBondContact O-CB 3.43Å; E110-L117 PolarHBondContact O-N 3.43Å; E110-F118 PolarHBondContact O-N 2.94Å; E110-F118 VanDerWaalsContact O-N 3.09Å
111	C	82.2	Confident	86.8	Confident	0 Å²	0	52.9 Å²	52.9	0%	0	31%	0.311	C	S	.	.	G	3₁₀ helix	trans	-100.2	3.8	176.2	-83.3	0	0	0	0	114.2	W100 V103 W104 T107 G108 T109 F118	W100-C111 PolarHBondContact NE1-O 3.38Å; V103-C111 WeakPolarHBondContact CG1-SG 3.35Å; W104-C111 HydrophobicContact CB-CB 3.87Å; W104-C111 HydrophobicContact CG-CB 4.31Å; T107-C111 PolarHBondContact OG1-SG 3.42Å; T107-C111 VanDerWaalsContact OG1-SG 3.34Å; G108-C111 PolarHBondContact O-N 3.48Å; T109-C111 PolarHBondContact O-N 3.24Å; T109-C111 VanDerWaalsContact O-N 3.17Å; C111-F118 WeakPolarHBondContact O-CD2 3.22Å
112	L	84.5	Confident	87.1	Confident	79 Å²	79	54.8 Å²	54.8	41%	0.414	31%	0.313	S	S	.	.	S	Bend	trans	-86	160.8	171.2	-63.9	177.7	0	0	0	110.8	T109 G114 G115 F118	T109-L112 HydrophobicContact CG2-CD1 4.42Å; T109-L112 WeakPolarHBondContact O-CB 2.87Å; T109-L112 PolarHBondContact O-N 2.91Å; T109-L112 VanDerWaalsContact O-N 3.11Å; L112-G114 PolarHBondContact O-N 3.34Å; L112-G115 PolarHBondContact O-N 3.34Å; L112-F118 WeakPolarHBondContact O-CB 3.36Å
113	P	82.6	Confident	87.2	Confident	92 Å²	92	51.3 Å²	51.3	60%	0.597	29%	0.292	S	S	*	.	T	Hydrogen-bonded Turn	trans	-44.8	130.4	169.2	-32.6	39	0	0	0	112.6	F118 I167	P113-F118 HydrophobicContact CG-CZ 4.48Å; P113-I167 HydrophobicContact CB-CG2 3.98Å
114	G	80.6	Confident	87.5	Confident	35 Å²	35	51.9 Å²	51.9	36%	0.361	29%	0.29	S	S	.	.	T	Hydrogen-bonded Turn	trans	89.2	-16	-172.2	0	0	0	0	0	115.4	L112 I167	L112-G114 PolarHBondContact O-N 3.34Å; G114-I167 WeakPolarHBondContact CA-O 3.21Å; G114-I167 PolarHBondContact N-O 2.84Å
115	G	86.7	Confident	87.7	Confident	9 Å²	9	47.7 Å²	47.7	9%	0.093	28%	0.276	C	S	.	.			trans	-78.9	150.9	176.8	0	0	0	0	0	113.8	E110 L112 L117 F118 G119	E110-G115 CarbonylContact O-C 3.44Å; E110-G115 WeakPolarHBondContact O-CA 3.29Å; L112-G115 PolarHBondContact O-N 3.34Å; G115-L117 PolarHBondContact O-N 3.13Å; G115-F118 WeakPolarHBondContact O-CB 3.36Å; G115-F118 PolarHBondContact O-N 3.34Å; G115-G119 PolarHBondContact O-N 3.14Å; G115-G119 VanDerWaalsContact O-N 3.12Å
116	N	88.6	Confident	87.9	Confident	21 Å²	21	46.7 Å²	46.7	11%	0.112	26%	0.26	C	S	.	.	H	α-helix	trans	-66.2	-40.2	-175.7	170.5	72.5	0	0	0	112.6	E110 G119 I120 N171	E110-N116 PolarHBondContact OE2-N 3.31Å; N116-G119 PolarHBondContact O-N 3.42Å; N116-I120 WeakPolarHBondContact O-CG1 3.49Å; N116-I120 PolarHBondContact O-N 2.9Å; N116-I120 VanDerWaalsContact O-N 3.09Å; N116-N171 WeakPolarHBondContact OD1-CB 3.37Å; N116-N171 PolarHBondContact OD1-N 3.13Å
117	L	87.4	Confident	88.1	Confident	39 Å²	39	40.6 Å²	40.6	20%	0.204	23%	0.228	C	C	.	.	H	α-helix	trans	-73.1	-33.5	-179.8	-64.3	174.7	0	0	0	111.7	V103 T107 E110 G115 G119 I120 L121	V103-L117 HydrophobicContact CG1-CD1 4.19Å; T107-L117 HydrophobicContact CG2-CD1 3.59Å; T107-L117 WeakPolarHBondContact OG1-CD1 3.28Å; E110-L117 HydrophobicContact CB-CB 4.44Å; E110-L117 HydrophobicContact CB-CD1 3.98Å; E110-L117 HydrophobicContact CB-CG 4.3Å; E110-L117 WeakPolarHBondContact O-CB 3.43Å; E110-L117 PolarHBondContact O-N 3.43Å; G115-L117 PolarHBondContact O-N 3.13Å; L117-G119 VanDerWaalsContact C-N 3.35Å; L117-I120 PolarHBondContact O-N 3.06Å; L117-L121 WeakPolarHBondContact O-CB 3.3Å; L117-L121 VanDerWaalsContact O-CG 3.32Å; L117-L121 WeakPolarHBondContact O-CG 3.36Å; L117-L121 PolarHBondContact O-N 2.83Å
118	F	89.9	Confident	88.4	Confident	35 Å²	35	39.8 Å²	39.8	15%	0.154	22%	0.224	C	C	.	.	H	α-helix	trans	-56.4	-49.7	168.3	178.6	-94.2	0	0	0	111.2	E110 C111 L112 P113 G115 I120 L121 F122 I167 I168	E110-F118 PolarHBondContact O-N 2.94Å; E110-F118 VanDerWaalsContact O-N 3.09Å; C111-F118 WeakPolarHBondContact O-CD2 3.22Å; L112-F118 WeakPolarHBondContact O-CB 3.36Å; P113-F118 HydrophobicContact CG-CZ 4.48Å; G115-F118 WeakPolarHBondContact O-CB 3.36Å; G115-F118 PolarHBondContact O-N 3.34Å; F118-I120 PolarHBondContact O-N 3.17Å; F118-L121 PolarHBondContact O-N 3.32Å; F118-F122 HydrophobicContact CE1-CB 4.48Å; F118-F122 HydrophobicContact CE1-CD2 4.42Å; F118-F122 HydrophobicContact CZ-CD2 4.1Å; F118-F122 WeakPolarHBondContact O-CB 3.27Å; F118-F122 PolarHBondContact O-N 3.49Å; F118-I167 HydrophobicContact CE1-CG2 3.8Å; F118-I167 HydrophobicContact CZ-CG2 4.48Å; F118-I168 HydrophobicContact CE1-CG1 4.13Å
119	G	89.8	Confident	88.6	Confident	0 Å²	0	42.6 Å²	42.6	0%	0	23%	0.23	C	C	.	.	H	α-helix	trans	-60.9	-44	-179.8	0	0	0	0	0	113.5	G115 N116 L117 L123	G115-G119 PolarHBondContact O-N 3.14Å; G115-G119 VanDerWaalsContact O-N 3.12Å; N116-G119 PolarHBondContact O-N 3.42Å; L117-G119 VanDerWaalsContact C-N 3.35Å; G119-L123 VanDerWaalsContact O-CB 3.28Å; G119-L123 WeakPolarHBondContact O-CB 3.41Å; G119-L123 PolarHBondContact O-N 3.39Å
120	I	91.8	Very high	89.2	Confident	13 Å²	13	38 Å²	38	7%	0.067	21%	0.205	C	C	.	.	H	α-helix	trans	-64.2	-45.6	177.9	-68	166.5	0	0	0	111.6	N116 L117 F118 Y124 I170 W174 L178 F401	N116-I120 WeakPolarHBondContact O-CG1 3.49Å; N116-I120 PolarHBondContact O-N 2.9Å; N116-I120 VanDerWaalsContact O-N 3.09Å; L117-I120 PolarHBondContact O-N 3.06Å; F118-I120 PolarHBondContact O-N 3.17Å; I120-Y124 WeakPolarHBondContact O-CB 3.47Å; I120-Y124 PolarHBondContact O-N 3.03Å; I120-I170 HydrophobicContact CG1-CG2 4.02Å; I120-W174 HydrophobicContact CD1-CB 3.79Å; I120-W174 HydrophobicContact CD1-CG 4.2Å; I120-L178 HydrophobicContact CD1-CD1 4.28Å; I120-L178 HydrophobicContact CG1-CD1 4.36Å; I120-L178 HydrophobicContact CG2-CD1 3.76Å; I120-F401 HydrophobicContact CG2-CD1 4.5Å; I120-F401 HydrophobicContact CG2-CE1 3.67Å; I120-F401 HydrophobicContact CG2-CZ 4.38Å
121	L	91.6	Very high	89.5	Confident	25 Å²	25	33.9 Å²	33.9	13%	0.131	19%	0.186	C	C	.	.	H	α-helix	trans	-66.7	-44.3	178.5	-72.5	174	0	0	0	111.9	V99 V103 L117 F118 Y124 F125	V99-L121 HydrophobicContact CG1-CD2 4.22Å; V103-L121 HydrophobicContact CB-CD1 4.06Å; V103-L121 HydrophobicContact CG1-CD1 4.28Å; V103-L121 HydrophobicContact CG2-CD1 4.16Å; L117-L121 WeakPolarHBondContact O-CB 3.3Å; L117-L121 VanDerWaalsContact O-CG 3.32Å; L117-L121 WeakPolarHBondContact O-CG 3.36Å; L117-L121 PolarHBondContact O-N 2.83Å; F118-L121 PolarHBondContact O-N 3.32Å; L121-Y124 PolarHBondContact O-N 2.82Å; L121-F125 HydrophobicContact CB-CE2 4.31Å; L121-F125 HydrophobicContact CD2-CE2 4.38Å; L121-F125 WeakPolarHBondContact O-CD2 3.28Å; L121-F125 PolarHBondContact O-N 2.88Å
122	F	92.3	Very high	89.8	Confident	76 Å²	76	39.2 Å²	39.2	33%	0.333	21%	0.209	S	C	.	.	H	α-helix	trans	-59.7	-48.8	177	-172.3	-74.8	0	0	0	110.6	F118 Y124 F125 F126 I158 I168	F118-F122 HydrophobicContact CE1-CB 4.48Å; F118-F122 HydrophobicContact CE1-CD2 4.42Å; F118-F122 HydrophobicContact CZ-CD2 4.1Å; F118-F122 WeakPolarHBondContact O-CB 3.27Å; F118-F122 PolarHBondContact O-N 3.49Å; F122-Y124 VanDerWaalsContact C-N 3.31Å; F122-Y124 PolarHBondContact O-N 3.29Å; F122-F125 PolarHBondContact O-N 2.97Å; F122-F126 HydrophobicContact CD1-CB 4.14Å; F122-F126 HydrophobicContact CE1-CB 3.98Å; F122-F126 HydrophobicContact CE1-CD1 4.48Å; F122-F126 HydrophobicContact CE1-CD2 4.44Å; F122-F126 HydrophobicContact CE1-CG 4.08Å; F122-F126 VanDerWaalsContact O-CB 3.25Å; F122-F126 WeakPolarHBondContact O-CB 3.36Å; F122-F126 PolarHBondContact O-N 2.8Å; F122-I158 HydrophobicContact CD1-CD1 3.89Å; F122-I158 HydrophobicContact CD1-CG1 4.38Å; F122-I158 HydrophobicContact CE1-CD1 4.07Å; F122-I158 HydrophobicContact CE1-CG1 4.14Å; F122-I168 HydrophobicContact CB-CD1 4.08Å; F122-I168 HydrophobicContact CD1-CD1 3.16Å; F122-I168 HydrophobicContact CD1-CG1 4.4Å; F122-I168 HydrophobicContact CD2-CD1 4.15Å; F122-I168 HydrophobicContact CE1-CD1 3.5Å; F122-I168 VanDerWaalsContact CE1-CD1 3.5Å; F122-I168 HydrophobicContact CE2-CD1 4.41Å; F122-I168 HydrophobicContact CG-CD1 3.53Å; F122-I168 HydrophobicContact CG-CG1 4.39Å; F122-I168 HydrophobicContact CZ-CD1 4.11Å
123	L	93.6	Very high	90	Very high	0 Å²	0	39.8 Å²	39.8	0%	0	21%	0.212	C	C	.	.	H	α-helix	trans	-58.2	-43.8	177.6	178.6	148	0	0	0	111.6	G119 A127 I158 I170 L405 A408	G119-L123 VanDerWaalsContact O-CB 3.28Å; G119-L123 WeakPolarHBondContact O-CB 3.41Å; G119-L123 PolarHBondContact O-N 3.39Å; L123-A127 WeakPolarHBondContact O-CB 3.43Å; L123-A127 PolarHBondContact O-N 3.22Å; L123-I158 HydrophobicContact CB-CD1 4.03Å; L123-I158 HydrophobicContact CG-CD1 4.27Å; L123-I170 HydrophobicContact CB-CD1 4.03Å; L123-I170 HydrophobicContact CD1-CD1 3.5Å; L123-I170 VanDerWaalsContact CD1-CD1 3.5Å; L123-I170 HydrophobicContact CG-CD1 4.38Å; L123-L405 HydrophobicContact CD1-CD2 3.88Å; L123-L405 HydrophobicContact CD1-CG 4.4Å; L123-L405 HydrophobicContact CD2-CD2 4.13Å; L123-L405 HydrophobicContact CD2-CG 4.04Å; L123-A408 HydrophobicContact CD1-CB 3.71Å
124	Y	94	Very high	90.1	Very high	50 Å²	50	37.6 Å²	37.6	20%	0.196	19%	0.193	C	C	.	.	H	α-helix	trans	-58.4	-53.3	177	177.5	-102	0	0	0	112	I120 L121 F122 A127 V128 V397 P400 F401	I120-Y124 WeakPolarHBondContact O-CB 3.47Å; I120-Y124 PolarHBondContact O-N 3.03Å; L121-Y124 PolarHBondContact O-N 2.82Å; F122-Y124 VanDerWaalsContact C-N 3.31Å; F122-Y124 PolarHBondContact O-N 3.29Å; Y124-A127 PolarHBondContact O-N 2.84Å; Y124-V128 HydrophobicContact CE1-CG2 4.11Å; Y124-V128 HydrophobicContact CE2-CG2 4.09Å; Y124-V128 WeakPolarHBondContact O-CG2 3.36Å; Y124-V128 PolarHBondContact O-N 3.38Å; Y124-V397 WeakPolarHBondContact CE2-O 3.25Å; Y124-P400 HydrophobicContact CD2-CB 3.94Å; Y124-P400 HydrophobicContact CD2-CG 4.4Å; Y124-P400 HydrophobicContact CE2-CB 3.95Å; Y124-P400 HydrophobicContact CE2-CG 3.89Å; Y124-F401 HydrophobicContact CD2-CD1 4.25Å; Y124-F401 AromaticContact CD2-CD2 3.99Å; Y124-F401 HydrophobicContact CD2-CD2 3.99Å; Y124-F401 AromaticContact CD2-CE1 3.87Å; Y124-F401 HydrophobicContact CD2-CE1 3.87Å; Y124-F401 AromaticContact CD2-CE2 3.59Å; Y124-F401 HydrophobicContact CD2-CE2 3.59Å; Y124-F401 HydrophobicContact CD2-CG 4.3Å; Y124-F401 AromaticContact CD2-CZ 3.52Å; Y124-F401 HydrophobicContact CD2-CZ 3.52Å; Y124-F401 HydrophobicContact CE2-CD2 4.37Å; Y124-F401 AromaticContact CE2-CE2 3.99Å; Y124-F401 HydrophobicContact CE2-CE2 3.99Å; Y124-F401 HydrophobicContact CE2-CZ 4.31Å; Y124-F401 HydrophobicContact CG-CE1 4.1Å; Y124-F401 HydrophobicContact CG-CE2 4.36Å; Y124-F401 AromaticContact CG-CZ 3.86Å; Y124-F401 HydrophobicContact CG-CZ 3.86Å
125	F	92.6	Very high	90.1	Very high	33 Å²	33	37.3 Å²	37.3	15%	0.145	19%	0.19	C	C	.	.	H	α-helix	trans	-66.6	-40.1	-178.4	-66.4	-55.4	0	0	0	112.2	V96 V99 L121 F122 V128 I129	V96-F125 HydrophobicContact CB-CE1 4.27Å; V96-F125 HydrophobicContact CB-CZ 4.36Å; V96-F125 HydrophobicContact CG1-CD1 4.26Å; V96-F125 HydrophobicContact CG1-CD2 3.94Å; V96-F125 HydrophobicContact CG1-CE1 4.26Å; V96-F125 HydrophobicContact CG1-CE2 3.94Å; V96-F125 HydrophobicContact CG1-CG 4.12Å; V96-F125 HydrophobicContact CG1-CZ 4.09Å; V96-F125 HydrophobicContact CG2-CD1 3.72Å; V96-F125 HydrophobicContact CG2-CE1 3.74Å; V96-F125 HydrophobicContact CG2-CG 4.3Å; V96-F125 HydrophobicContact CG2-CZ 4.32Å; V99-F125 HydrophobicContact CB-CZ 4.11Å; V99-F125 HydrophobicContact CG1-CZ 3.96Å; L121-F125 HydrophobicContact CB-CE2 4.31Å; L121-F125 HydrophobicContact CD2-CE2 4.38Å; L121-F125 WeakPolarHBondContact O-CD2 3.28Å; L121-F125 PolarHBondContact O-N 2.88Å; F122-F125 PolarHBondContact O-N 2.97Å; F125-V128 PolarHBondContact O-N 2.85Å; F125-I129 WeakPolarHBondContact O-CB 3.48Å; F125-I129 WeakPolarHBondContact O-CD1 3.31Å; F125-I129 VanDerWaalsContact O-CG1 3.26Å; F125-I129 WeakPolarHBondContact O-CG1 3.36Å; F125-I129 PolarHBondContact O-N 3.45Å
126	F	92.9	Very high	89.8	Confident	71 Å²	71	43.6 Å²	43.6	31%	0.311	22%	0.221	S	C	.	.	H	α-helix	trans	-65.9	-39.6	177.2	-165.1	-120.7	0	0	0	111.8	F122 I129 G130 A154 F157 I158	F122-F126 HydrophobicContact CD1-CB 4.14Å; F122-F126 HydrophobicContact CE1-CB 3.98Å; F122-F126 HydrophobicContact CE1-CD1 4.48Å; F122-F126 HydrophobicContact CE1-CD2 4.44Å; F122-F126 HydrophobicContact CE1-CG 4.08Å; F122-F126 VanDerWaalsContact O-CB 3.25Å; F122-F126 WeakPolarHBondContact O-CB 3.36Å; F122-F126 PolarHBondContact O-N 2.8Å; F126-I129 PolarHBondContact O-N 3.34Å; F126-G130 PolarHBondContact O-N 3.15Å; F126-A154 HydrophobicContact CD1-CB 3.55Å; F126-A154 WeakPolarHBondContact CD1-O 3.32Å; F126-A154 HydrophobicContact CE1-CB 3.88Å; F126-A154 VanDerWaalsContact CE1-O 3.28Å; F126-A154 WeakPolarHBondContact CE1-O 3.33Å; F126-A154 HydrophobicContact CG-CB 4.26Å; F126-F157 HydrophobicContact CE1-CB 4.28Å; F126-I158 HydrophobicContact CB-CD1 4.18Å; F126-I158 HydrophobicContact CD1-CD1 3.65Å; F126-I158 HydrophobicContact CD1-CG1 3.71Å; F126-I158 HydrophobicContact CE1-CG1 4.1Å; F126-I158 HydrophobicContact CG-CD1 4.3Å
127	A	94.3	Very high	89.3	Confident	0 Å²	0	46 Å²	46	0%	0	23%	0.233	C	C	.	.	H	α-helix	trans	-64.4	-43.6	172.6	0	0	0	0	0	112.3	L123 Y124 I129 G130 G131 M151 A154 P400	L123-A127 WeakPolarHBondContact O-CB 3.43Å; L123-A127 PolarHBondContact O-N 3.22Å; Y124-A127 PolarHBondContact O-N 2.84Å; A127-I129 VanDerWaalsContact C-N 3.31Å; A127-I129 PolarHBondContact O-N 2.89Å; A127-G130 PolarHBondContact O-N 2.9Å; A127-G131 PolarHBondContact O-N 3.4Å; A127-M151 HydrophobicContact CB-CB 4.22Å; A127-M151 HydrophobicContact CB-CG 4.4Å; A127-M151 VanDerWaalsContact O-CG 3.26Å; A127-M151 WeakPolarHBondContact O-CG 2.95Å; A127-A154 HydrophobicContact CB-CB 4.43Å; A127-P400 HydrophobicContact CB-CB 3.98Å
128	V	92.5	Very high	88.3	Confident	30 Å²	30	52.2 Å²	52.2	18%	0.182	26%	0.258	C	S	.	.	H	α-helix	trans	-60.5	-40.5	174.4	169	0	0	0	0	111.5	Y124 F125 K132 P400	Y124-V128 HydrophobicContact CE1-CG2 4.11Å; Y124-V128 HydrophobicContact CE2-CG2 4.09Å; Y124-V128 WeakPolarHBondContact O-CG2 3.36Å; Y124-V128 PolarHBondContact O-N 3.38Å; F125-V128 PolarHBondContact O-N 2.85Å; V128-K132 HydrophobicContact CG1-CD 4.21Å; V128-K132 WeakPolarHBondContact O-CB 3.36Å; V128-K132 WeakPolarHBondContact O-CG 3.37Å; V128-K132 PolarHBondContact O-N 2.91Å; V128-P400 HydrophobicContact CG2-CB 3.86Å; V128-P400 HydrophobicContact CG2-CG 3.62Å
129	I	91.4	Very high	87.3	Confident	89 Å²	89	54.5 Å²	54.5	46%	0.456	27%	0.271	S	S	.	.	H	α-helix	trans	-65.7	-49.7	175.4	-70.2	164	0	0	0	110.5	F125 F126 A127 G131 K132 I133	F125-I129 WeakPolarHBondContact O-CB 3.48Å; F125-I129 WeakPolarHBondContact O-CD1 3.31Å; F125-I129 VanDerWaalsContact O-CG1 3.26Å; F125-I129 WeakPolarHBondContact O-CG1 3.36Å; F125-I129 PolarHBondContact O-N 3.45Å; F126-I129 PolarHBondContact O-N 3.34Å; A127-I129 VanDerWaalsContact C-N 3.31Å; A127-I129 PolarHBondContact O-N 2.89Å; I129-G131 VanDerWaalsContact C-N 3.33Å; I129-G131 PolarHBondContact O-N 2.77Å; I129-K132 PolarHBondContact O-N 3.46Å; I129-K132 VanDerWaalsContact O-N 3.14Å; I129-I133 HydrophobicContact CG2-CD1 3.69Å; I129-I133 HydrophobicContact CG2-CG1 4.33Å; I129-I133 WeakPolarHBondContact O-CG1 3.27Å; I129-I133 PolarHBondContact O-N 2.95Å
130	G	91.5	Very high	85.6	Confident	12 Å²	12	66.7 Å²	66.7	12%	0.124	32%	0.317	C	S	.	.	H	α-helix	trans	-56.5	-45.2	177.3	0	0	0	0	0	112.5	F126 A127 I133 F134	F126-G130 PolarHBondContact O-N 3.15Å; A127-G130 PolarHBondContact O-N 2.9Å; G130-I133 PolarHBondContact O-N 3.45Å; G130-F134 WeakPolarHBondContact O-CD2 3.23Å; G130-F134 PolarHBondContact O-N 2.97Å
131	G	89.8	Confident	83.9	Confident	3 Å²	3	71.3 Å²	71.3	3%	0.031	35%	0.346	C	S	.	.	H	α-helix	trans	-63.8	-39.7	175.2	0	0	0	0	0	113.7	A127 I129 G135 A147	A127-G131 PolarHBondContact O-N 3.4Å; I129-G131 VanDerWaalsContact C-N 3.33Å; I129-G131 PolarHBondContact O-N 2.77Å; G131-G135 PolarHBondContact O-N 3.35Å; G131-A147 VanDerWaalsContact CA-O 3.29Å; G131-A147 WeakPolarHBondContact CA-O 3.28Å; G131-A147 WeakPolarHBondContact O-CB 3.5Å
132	K	87.9	Confident	82.3	Confident	111 Å²	111	72.8 Å²	72.8	48%	0.483	35%	0.354	S	S	.	.	H	α-helix	trans	-64.5	-43.8	173.4	-78.4	173.8	179.5	174.5	0	111.7	N92 V128 I129 G135 L136	N92-K132 PolarHBondContact OD1-NZ 2.88Å; V128-K132 HydrophobicContact CG1-CD 4.21Å; V128-K132 WeakPolarHBondContact O-CB 3.36Å; V128-K132 WeakPolarHBondContact O-CG 3.37Å; V128-K132 PolarHBondContact O-N 2.91Å; I129-K132 PolarHBondContact O-N 3.46Å; I129-K132 VanDerWaalsContact O-N 3.14Å; K132-G135 PolarHBondContact O-N 3.45Å; K132-L136 VanDerWaalsContact O-CG 3.29Å; K132-L136 WeakPolarHBondContact O-CG 3.36Å; K132-L136 PolarHBondContact O-N 2.97Å
133	I	88.3	Confident	80.9	Confident	92 Å²	92	70.4 Å²	70.4	47%	0.472	35%	0.346	S	S	.	.	H	α-helix	trans	-59.2	-52.3	177.5	-69.9	167.6	0	0	0	110	I129 G130 G135 L136 I137	I129-I133 HydrophobicContact CG2-CD1 3.69Å; I129-I133 HydrophobicContact CG2-CG1 4.33Å; I129-I133 WeakPolarHBondContact O-CG1 3.27Å; I129-I133 PolarHBondContact O-N 2.95Å; G130-I133 PolarHBondContact O-N 3.45Å; I133-G135 VanDerWaalsContact C-N 3.33Å; I133-G135 PolarHBondContact O-N 3.23Å; I133-L136 WeakPolarHBondContact O-CB 3.41Å; I133-L136 PolarHBondContact O-N 3.44Å; I133-L136 VanDerWaalsContact O-N 3.09Å; I133-I137 WeakPolarHBondContact O-CG1 3.37Å; I133-I137 PolarHBondContact O-N 3.24Å
134	F	85.6	Confident	79.5	Confident	46 Å²	46	73.7 Å²	73.7	20%	0.202	37%	0.367	C	S	.	.	H	α-helix	trans	-63.4	-37.3	179.3	-87.6	-107.2	0	0	0	112.7	G130 L136 I137 L145 L149 G150 L153	G130-F134 WeakPolarHBondContact O-CD2 3.23Å; G130-F134 PolarHBondContact O-N 2.97Å; F134-L136 VanDerWaalsContact C-N 3.27Å; F134-L136 PolarHBondContact O-N 2.9Å; F134-I137 PolarHBondContact O-N 3.43Å; F134-L145 HydrophobicContact CD1-CB 4.34Å; F134-L145 HydrophobicContact CD1-CD1 4.11Å; F134-L145 HydrophobicContact CE1-CD1 4.46Å; F134-L149 HydrophobicContact CD1-CB 4.43Å; F134-L149 HydrophobicContact CD1-CD2 4.22Å; F134-L149 HydrophobicContact CD1-CG 4.41Å; F134-L149 HydrophobicContact CE1-CD2 3.96Å; F134-L149 HydrophobicContact CE1-CG 4.21Å; F134-G150 VanDerWaalsContact CD2-CA 3.48Å; F134-L153 HydrophobicContact CE1-CD1 4.06Å; F134-L153 HydrophobicContact CE2-CD1 4.15Å; F134-L153 HydrophobicContact CZ-CD1 3.51Å
135	G	80.4	Confident	78.6	Confident	29 Å²	29	73.6 Å²	73.6	30%	0.299	37%	0.37	S	S	.	.	H	α-helix	trans	-68.2	-20.2	174.4	0	0	0	0	0	115	G131 K132 I133	G131-G135 PolarHBondContact O-N 3.35Å; K132-G135 PolarHBondContact O-N 3.45Å; I133-G135 VanDerWaalsContact C-N 3.33Å; I133-G135 PolarHBondContact O-N 3.23Å
136	L	80.3	Confident	78	Confident	141 Å²	141	72.8 Å²	72.8	74%	0.738	37%	0.368	S	S	*	.	H	α-helix	trans	-83	-19.6	172.9	-72.5	169.5	0	0	0	112.9	K132 I133 F134 K138	K132-L136 VanDerWaalsContact O-CG 3.29Å; K132-L136 WeakPolarHBondContact O-CG 3.36Å; K132-L136 PolarHBondContact O-N 2.97Å; I133-L136 WeakPolarHBondContact O-CB 3.41Å; I133-L136 PolarHBondContact O-N 3.44Å; I133-L136 VanDerWaalsContact O-N 3.09Å; F134-L136 VanDerWaalsContact C-N 3.27Å; F134-L136 PolarHBondContact O-N 2.9Å; L136-K138 PolarHBondContact O-N 2.83Å
137	I	77.9	Confident	77.7	Confident	70 Å²	70	71 Å²	71	36%	0.359	37%	0.367	S	S	.	.			trans	-74.4	79.1	175.8	-58.2	169	0	0	0	109.1	I133 F134 I139 L145	I133-I137 WeakPolarHBondContact O-CG1 3.37Å; I133-I137 PolarHBondContact O-N 3.24Å; F134-I137 PolarHBondContact O-N 3.43Å; I137-I139 HydrophobicContact CG2-CD1 4.39Å; I137-I139 HydrophobicContact CG2-CG1 4.22Å; I137-L145 HydrophobicContact CB-CD1 4.16Å; I137-L145 HydrophobicContact CG2-CD1 3.87Å
138	K	66.7	Low	77.4	Confident	170 Å²	170	71.6 Å²	71.6	74%	0.739	37%	0.37	S	S	*	.			trans	-93.2	96	170.9	-68.4	-173.8	179.1	-176.6	0	109.6	L136	L136-K138 PolarHBondContact O-N 2.83Å
139	I	67.6	Low	77.2	Confident	84 Å²	84	70.7 Å²	70.7	43%	0.431	36%	0.364	S	S	.	.			trans	-75.6	125.8	171.1	-63.5	164.1	0	0	0	107.6	I137 T141 L142	I137-I139 HydrophobicContact CG2-CD1 4.39Å; I137-I139 HydrophobicContact CG2-CG1 4.22Å; I139-T141 PolarHBondContact O-N 3.42Å; I139-L142 HydrophobicContact CB-CB 4.11Å; I139-L142 HydrophobicContact CB-CD1 4.12Å; I139-L142 HydrophobicContact CB-CG 4.22Å; I139-L142 HydrophobicContact CD1-CD1 3.92Å; I139-L142 HydrophobicContact CG2-CB 4.28Å; I139-L142 HydrophobicContact CG2-CD1 3.89Å; I139-L142 HydrophobicContact CG2-CG 3.88Å; I139-L142 PolarHBondContact O-N 3.38Å; I139-L142 VanDerWaalsContact O-O 3.11Å
140	R	55.2	Low	77.2	Confident	255 Å²	255	66.5 Å²	66.5	96%	0.962	34%	0.342	S	S	*	.	T	Hydrogen-bonded Turn	trans	-48.6	-26.9	-170.5	-172.4	70.3	153.6	126	-1.1	115.4
141	T	56.2	Low	77.3	Confident	110 Å²	110	66.8 Å²	66.8	68%	0.675	34%	0.341	S	S	*	.	T	Hydrogen-bonded Turn	trans	-109.5	-1.9	-174.2	-30.9	0	0	0	0	113.4	I139	I139-T141 PolarHBondContact O-N 3.42Å
142	L	58.1	Low	77.5	Confident	56 Å²	56	66.6 Å²	66.6	29%	0.293	34%	0.339	S	S	.	.	S	Bend	trans	-124.4	151.3	-171.5	-58.8	-176.7	0	0	0	111.6	I139 L509 L513	I139-L142 HydrophobicContact CB-CB 4.11Å; I139-L142 HydrophobicContact CB-CD1 4.12Å; I139-L142 HydrophobicContact CB-CG 4.22Å; I139-L142 HydrophobicContact CD1-CD1 3.92Å; I139-L142 HydrophobicContact CG2-CB 4.28Å; I139-L142 HydrophobicContact CG2-CD1 3.89Å; I139-L142 HydrophobicContact CG2-CG 3.88Å; I139-L142 PolarHBondContact O-N 3.38Å; I139-L142 VanDerWaalsContact O-O 3.11Å; L142-L509 HydrophobicContact CD1-CD1 4.08Å; L142-L509 HydrophobicContact CD2-CD1 3.29Å; L142-L509 HydrophobicContact CG-CD1 4.31Å; L142-L513 HydrophobicContact CD2-CD1 4.29Å; L142-L513 HydrophobicContact CD2-CD2 4.07Å; L142-L513 HydrophobicContact CD2-CG 4.13Å
143	P	61.7	Low	77.7	Confident	27 Å²	27	62.6 Å²	62.6	18%	0.175	32%	0.323	C	S	.	.	P	Polyproline II helix	trans	-61.9	153	168.1	25	-29.5	0	0	0	110.3	L145 A508	P143-L145 PolarHBondContact O-N 3.39Å; P143-A508 HydrophobicContact CG-CB 4.35Å; P143-A508 WeakPolarHBondContact CG-O 3.3Å
144	P	65.8	Low	78	Confident	68 Å²	68	58.4 Å²	58.4	44%	0.442	30%	0.302	S	S	.	.	P	Polyproline II helix	trans	-58.3	138	-179	25.6	-34.8	0	0	0	110.7
145	L	73.4	Confident	78.4	Confident	48 Å²	48	56.2 Å²	56.2	25%	0.251	29%	0.293	S	S	.	.	P	Polyproline II helix	trans	-60	136.1	176.4	-72.6	174.7	0	0	0	109.9	F134 I137 P143 A147 P505	F134-L145 HydrophobicContact CD1-CB 4.34Å; F134-L145 HydrophobicContact CD1-CD1 4.11Å; F134-L145 HydrophobicContact CE1-CD1 4.46Å; I137-L145 HydrophobicContact CB-CD1 4.16Å; I137-L145 HydrophobicContact CG2-CD1 3.87Å; P143-L145 PolarHBondContact O-N 3.39Å; L145-A147 PolarHBondContact O-N 3.01Å; L145-A147 VanDerWaalsContact O-N 3.11Å; L145-P505 HydrophobicContact CD2-CB 4.33Å
146	P	80.7	Confident	78.9	Confident	16 Å²	16	56.8 Å²	56.8	10%	0.104	29%	0.287	C	S	.	.	P	Polyproline II helix	trans	-58.5	118.7	179.6	-25.6	34.6	0	0	0	111.3	L148 L149 V250 A504 A508	P146-L148 PolarHBondContact O-N 3.18Å; P146-L149 VanDerWaalsContact O-CB 3.23Å; P146-L149 WeakPolarHBondContact O-CB 3.5Å; P146-L149 PolarHBondContact O-N 3.03Å; P146-V250 HydrophobicContact CB-CG2 4.45Å; P146-V250 HydrophobicContact CG-CG2 4.13Å; P146-A504 HydrophobicContact CG-CB 4.45Å; P146-A508 HydrophobicContact CG-CB 4.41Å
147	A	87.2	Confident	79.5	Confident	34 Å²	34	55.2 Å²	55.2	28%	0.281	27%	0.274	S	S	.	.	H	α-helix	trans	-57.4	-25	178.9	0	0	0	0	0	113.1	G131 L145 L149 G150 M151	G131-A147 VanDerWaalsContact CA-O 3.29Å; G131-A147 WeakPolarHBondContact CA-O 3.28Å; G131-A147 WeakPolarHBondContact O-CB 3.5Å; L145-A147 PolarHBondContact O-N 3.01Å; L145-A147 VanDerWaalsContact O-N 3.11Å; A147-L149 PolarHBondContact O-N 2.86Å; A147-G150 PolarHBondContact O-N 2.95Å; A147-M151 PolarHBondContact O-N 2.97Å
148	L	87.6	Confident	80.2	Confident	12 Å²	12	52.1 Å²	52.1	6%	0.063	26%	0.258	C	S	.	.	H	α-helix	trans	-52.4	-38.8	171.1	-50.7	174	0	0	0	112.3	P146 M151 L152 A249 Q399 F403 A463 T464	P146-L148 PolarHBondContact O-N 3.18Å; L148-M151 PolarHBondContact O-N 2.94Å; L148-L152 WeakPolarHBondContact O-CB 3.09Å; L148-L152 PolarHBondContact O-N 3.35Å; L148-A249 HydrophobicContact CD1-CB 3.89Å; L148-Q399 HydrophobicContact CD2-CG 3.65Å; L148-F403 HydrophobicContact CB-CD1 4.15Å; L148-F403 HydrophobicContact CB-CE1 3.94Å; L148-F403 HydrophobicContact CB-CE2 4.4Å; L148-F403 HydrophobicContact CB-CG 4.45Å; L148-F403 HydrophobicContact CB-CZ 4.06Å; L148-F403 HydrophobicContact CD1-CZ 4.03Å; L148-F403 HydrophobicContact CD2-CD2 4Å; L148-F403 HydrophobicContact CD2-CE2 3.6Å; L148-F403 HydrophobicContact CD2-CZ 3.92Å; L148-F403 HydrophobicContact CG-CE2 4.38Å; L148-F403 HydrophobicContact CG-CZ 4.22Å; L148-A463 HydrophobicContact CD1-CB 4.12Å; L148-T464 HydrophobicContact CD1-CG2 3.95Å
149	L	88.3	Confident	81.4	Confident	11 Å²	11	49.4 Å²	49.4	6%	0.058	24%	0.243	C	C	.	.	H	α-helix	trans	-65.6	-42.3	-179.5	-173.3	63.2	0	0	0	111.3	F134 P146 A147 M151 L152 L153 L501 P505	F134-L149 HydrophobicContact CD1-CB 4.43Å; F134-L149 HydrophobicContact CD1-CD2 4.22Å; F134-L149 HydrophobicContact CD1-CG 4.41Å; F134-L149 HydrophobicContact CE1-CD2 3.96Å; F134-L149 HydrophobicContact CE1-CG 4.21Å; P146-L149 VanDerWaalsContact O-CB 3.23Å; P146-L149 WeakPolarHBondContact O-CB 3.5Å; P146-L149 PolarHBondContact O-N 3.03Å; A147-L149 PolarHBondContact O-N 2.86Å; L149-M151 VanDerWaalsContact C-N 3.35Å; L149-L152 PolarHBondContact O-N 3.5Å; L149-L153 HydrophobicContact CD1-CD1 4.48Å; L149-L153 HydrophobicContact CG-CD1 4.12Å; L149-L153 WeakPolarHBondContact O-CB 3.46Å; L149-L153 WeakPolarHBondContact O-CG 3.42Å; L149-L153 PolarHBondContact O-N 3.48Å; L149-L501 HydrophobicContact CD1-CD1 3.87Å; L149-P505 HydrophobicContact CD2-CB 4.23Å; L149-P505 HydrophobicContact CD2-CG 4.12Å
150	G	91.1	Very high	82.4	Confident	1 Å²	1	47.5 Å²	47.5	1%	0.01	23%	0.234	C	C	.	.	H	α-helix	trans	-66.2	-34.9	175.5	0	0	0	0	0	113.2	F134 A147 A154	F134-G150 VanDerWaalsContact CD2-CA 3.48Å; A147-G150 PolarHBondContact O-N 2.95Å; G150-A154 WeakPolarHBondContact O-CB 3.11Å; G150-A154 PolarHBondContact O-N 3Å
151	M	94.1	Very high	84	Confident	18 Å²	18	38 Å²	38	9%	0.089	20%	0.204	C	C	.	.	H	α-helix	trans	-66.5	-42.3	174	-66.1	170.4	-179.3	0	0	111.8	A127 A147 L148 L149 G155 Q399 P400 F403 G404	A127-M151 HydrophobicContact CB-CB 4.22Å; A127-M151 HydrophobicContact CB-CG 4.4Å; A127-M151 VanDerWaalsContact O-CG 3.26Å; A127-M151 WeakPolarHBondContact O-CG 2.95Å; A147-M151 PolarHBondContact O-N 2.97Å; L148-M151 PolarHBondContact O-N 2.94Å; L149-M151 VanDerWaalsContact C-N 3.35Å; M151-G155 PolarHBondContact O-N 3.49Å; M151-Q399 HydrophobicContact SD-CG 3.92Å; M151-Q399 PolarHBondContact SD-NE2 3.3Å; M151-P400 HydrophobicContact CE-CG 4.13Å; M151-P400 HydrophobicContact SD-CB 4.43Å; M151-P400 HydrophobicContact SD-CG 4.28Å; M151-F403 HydrophobicContact CB-CB 3.72Å; M151-G404 WeakPolarHBondContact O-CA 3.22Å
152	L	93.1	Very high	85.2	Confident	0 Å²	0	37 Å²	37	0%	0	20%	0.2	C	C	.	.	H	α-helix	trans	-68.6	-43.7	177.9	173	146.8	0	0	0	112.4	L148 L149 A154 G155 F156 F403 G407 F497 I500	L148-L152 WeakPolarHBondContact O-CB 3.09Å; L148-L152 PolarHBondContact O-N 3.35Å; L149-L152 PolarHBondContact O-N 3.5Å; L152-A154 VanDerWaalsContact C-N 3.32Å; L152-A154 PolarHBondContact O-N 3.39Å; L152-G155 PolarHBondContact O-N 2.81Å; L152-F156 PolarHBondContact O-N 3.05Å; L152-F403 WeakPolarHBondContact CA-O 3.23Å; L152-F403 HydrophobicContact CB-CB 4.26Å; L152-F403 HydrophobicContact CB-CD1 4.23Å; L152-F403 HydrophobicContact CD1-CD1 4.34Å; L152-G407 WeakPolarHBondContact O-CA 3.36Å; L152-F497 HydrophobicContact CD1-CD2 3.85Å; L152-F497 HydrophobicContact CD1-CE2 4.14Å; L152-F497 HydrophobicContact CD2-CD2 3.89Å; L152-F497 HydrophobicContact CD2-CE2 3.34Å; L152-F497 HydrophobicContact CD2-CZ 3.87Å; L152-F497 HydrophobicContact CG-CD2 3.91Å; L152-F497 HydrophobicContact CG-CE2 3.68Å; L152-I500 HydrophobicContact CD1-CB 4.08Å; L152-I500 HydrophobicContact CD1-CD1 3.98Å; L152-I500 HydrophobicContact CD1-CG2 3.8Å
153	L	93.3	Very high	86.4	Confident	27 Å²	27	39.3 Å²	39.3	14%	0.141	22%	0.216	C	C	.	.	H	α-helix	trans	-64.9	-35.4	175.9	-73	172.2	0	0	0	112.2	F134 L149 G155 F156 F157 L501	F134-L153 HydrophobicContact CE1-CD1 4.06Å; F134-L153 HydrophobicContact CE2-CD1 4.15Å; F134-L153 HydrophobicContact CZ-CD1 3.51Å; L149-L153 HydrophobicContact CD1-CD1 4.48Å; L149-L153 HydrophobicContact CG-CD1 4.12Å; L149-L153 WeakPolarHBondContact O-CB 3.46Å; L149-L153 WeakPolarHBondContact O-CG 3.42Å; L149-L153 PolarHBondContact O-N 3.48Å; L153-G155 PolarHBondContact O-N 3.41Å; L153-F156 PolarHBondContact O-N 3.28Å; L153-F157 HydrophobicContact CB-CD2 4.41Å; L153-F157 HydrophobicContact CB-CE2 4.06Å; L153-F157 WeakPolarHBondContact O-CD2 3.36Å; L153-F157 WeakPolarHBondContact O-CG 3.38Å; L153-F157 PolarHBondContact O-N 3.4Å; L153-L501 HydrophobicContact CD2-CD1 3.98Å
154	A	94	Very high	87.5	Confident	4 Å²	4	40.8 Å²	40.8	3%	0.033	22%	0.222	C	C	.	.	H	α-helix	trans	-58.8	-46.9	174	0	0	0	0	0	112.1	F126 A127 G150 L152 F157 I158	F126-A154 HydrophobicContact CD1-CB 3.55Å; F126-A154 WeakPolarHBondContact CD1-O 3.32Å; F126-A154 HydrophobicContact CE1-CB 3.88Å; F126-A154 VanDerWaalsContact CE1-O 3.28Å; F126-A154 WeakPolarHBondContact CE1-O 3.33Å; F126-A154 HydrophobicContact CG-CB 4.26Å; A127-A154 HydrophobicContact CB-CB 4.43Å; G150-A154 WeakPolarHBondContact O-CB 3.11Å; G150-A154 PolarHBondContact O-N 3Å; L152-A154 VanDerWaalsContact C-N 3.32Å; L152-A154 PolarHBondContact O-N 3.39Å; A154-F157 PolarHBondContact O-N 2.88Å; A154-I158 WeakPolarHBondContact O-CG1 3.5Å; A154-I158 PolarHBondContact O-N 3.31Å; A154-I158 VanDerWaalsContact O-N 3.13Å
155	G	93.3	Very high	88.2	Confident	0 Å²	0	39 Å²	39	0%	0	21%	0.211	C	C	.	.	H	α-helix	trans	-60.7	-43.7	173.5	0	0	0	0	0	113.1	M151 L152 L153 F157 I158 R159 G404 A408	M151-G155 PolarHBondContact O-N 3.49Å; L152-G155 PolarHBondContact O-N 2.81Å; L153-G155 PolarHBondContact O-N 3.41Å; G155-F157 PolarHBondContact O-N 3.11Å; G155-I158 WeakPolarHBondContact O-CB 3.35Å; G155-I158 PolarHBondContact O-N 3.43Å; G155-R159 PolarHBondContact O-N 2.98Å; G155-R159 VanDerWaalsContact O-N 3.16Å; G155-G404 VanDerWaalsContact CA-O 3.29Å; G155-G404 WeakPolarHBondContact CA-O 3.48Å; G155-A408 WeakPolarHBondContact O-CA 3.21Å
156	F	92.5	Very high	88.5	Confident	41 Å²	41	42.4 Å²	42.4	18%	0.18	23%	0.229	C	C	.	.	H	α-helix	trans	-61.4	-42.1	177.6	179.1	-97.8	0	0	0	112.5	L152 L153 R159 N160 G407 V410 V412 F497	L152-F156 PolarHBondContact O-N 3.05Å; L153-F156 PolarHBondContact O-N 3.28Å; F156-R159 PolarHBondContact O-N 3.17Å; F156-N160 VanDerWaalsContact CD2-ND2 3.35Å; F156-N160 WeakPolarHBondContact CD2-ND2 3.45Å; F156-N160 WeakPolarHBondContact CE2-ND2 3.46Å; F156-N160 WeakPolarHBondContact O-CB 3.05Å; F156-N160 PolarHBondContact O-N 3.05Å; F156-N160 PolarHBondContact O-ND2 3.17Å; F156-G407 VanDerWaalsContact CA-O 3.27Å; F156-G407 WeakPolarHBondContact CA-O 3.33Å; F156-G407 PolarHBondContact N-O 3.17Å; F156-V410 HydrophobicContact CD2-CB 4.41Å; F156-V410 HydrophobicContact CD2-CG1 4.36Å; F156-V410 HydrophobicContact CE2-CG1 4.26Å; F156-V412 HydrophobicContact CE1-CG2 4.42Å; F156-V412 HydrophobicContact CE2-CG2 3.71Å; F156-V412 HydrophobicContact CZ-CG2 3.37Å; F156-F497 HydrophobicContact CB-CE2 4.17Å; F156-F497 HydrophobicContact CB-CZ 4.12Å; F156-F497 HydrophobicContact CD2-CE1 4.11Å; F156-F497 AromaticContact CD2-CE2 3.97Å; F156-F497 HydrophobicContact CD2-CE2 3.97Å; F156-F497 AromaticContact CD2-CZ 3.38Å; F156-F497 HydrophobicContact CD2-CZ 3.38Å; F156-F497 HydrophobicContact CE2-CE1 4.18Å; F156-F497 AromaticContact CE2-CZ 3.88Å; F156-F497 HydrophobicContact CE2-CZ 3.88Å; F156-F497 HydrophobicContact CG-CE2 4.36Å; F156-F497 AromaticContact CG-CZ 3.85Å; F156-F497 HydrophobicContact CG-CZ 3.85Å
157	F	92.9	Very high	88.6	Confident	108 Å²	108	45.1 Å²	45.1	47%	0.474	24%	0.243	S	C	.	.	H	α-helix	trans	-67.5	-34.8	176.2	-69.8	-52.4	0	0	0	113.1	F126 L153 A154 G155 T161	F126-F157 HydrophobicContact CE1-CB 4.28Å; L153-F157 HydrophobicContact CB-CD2 4.41Å; L153-F157 HydrophobicContact CB-CE2 4.06Å; L153-F157 WeakPolarHBondContact O-CD2 3.36Å; L153-F157 WeakPolarHBondContact O-CG 3.38Å; L153-F157 PolarHBondContact O-N 3.4Å; A154-F157 PolarHBondContact O-N 2.88Å; G155-F157 PolarHBondContact O-N 3.11Å; F157-T161 VanDerWaalsContact O-CB 3.3Å; F157-T161 WeakPolarHBondContact O-CB 3.26Å; F157-T161 PolarHBondContact O-N 2.95Å; F157-T161 VanDerWaalsContact O-N 3.17Å; F157-T161 PolarHBondContact O-OG1 3.44Å
158	I	91.8	Very high	88.4	Confident	5 Å²	5	44.1 Å²	44.1	3%	0.026	23%	0.232	C	C	.	.	H	α-helix	trans	-58	-50.4	172.6	-74.2	168.6	0	0	0	110.3	F122 L123 F126 A154 G155 I164 S165 I168	F122-I158 HydrophobicContact CD1-CD1 3.89Å; F122-I158 HydrophobicContact CD1-CG1 4.38Å; F122-I158 HydrophobicContact CE1-CD1 4.07Å; F122-I158 HydrophobicContact CE1-CG1 4.14Å; L123-I158 HydrophobicContact CB-CD1 4.03Å; L123-I158 HydrophobicContact CG-CD1 4.27Å; F126-I158 HydrophobicContact CB-CD1 4.18Å; F126-I158 HydrophobicContact CD1-CD1 3.65Å; F126-I158 HydrophobicContact CD1-CG1 3.71Å; F126-I158 HydrophobicContact CE1-CG1 4.1Å; F126-I158 HydrophobicContact CG-CD1 4.3Å; A154-I158 WeakPolarHBondContact O-CG1 3.5Å; A154-I158 PolarHBondContact O-N 3.31Å; A154-I158 VanDerWaalsContact O-N 3.13Å; G155-I158 WeakPolarHBondContact O-CB 3.35Å; G155-I158 PolarHBondContact O-N 3.43Å; I158-I164 HydrophobicContact CB-CG2 4.38Å; I158-I164 HydrophobicContact CG1-CG2 4.27Å; I158-I164 HydrophobicContact CG2-CG2 4.31Å; I158-S165 PolarHBondContact O-N 3.37Å; I158-I168 HydrophobicContact CG1-CD1 4.33Å; I158-I168 HydrophobicContact CG2-CB 4.08Å; I158-I168 HydrophobicContact CG2-CD1 3.99Å; I158-I168 HydrophobicContact CG2-CG2 3.69Å
159	R	90.7	Very high	88	Confident	112 Å²	112	49.3 Å²	49.3	42%	0.423	26%	0.256	S	S	.	.	H	α-helix	trans	-69.6	-33.7	-176.8	-177.2	58.9	170.6	-142.2	-1.1	113.9	G155 F156 A408	G155-R159 PolarHBondContact O-N 2.98Å; G155-R159 VanDerWaalsContact O-N 3.16Å; F156-R159 PolarHBondContact O-N 3.17Å; R159-A408 WeakPolarHBondContact CB-O 3.48Å; R159-A408 VanDerWaalsContact CD-O 3.31Å; R159-A408 WeakPolarHBondContact CD-O 3.45Å; R159-A408 VanDerWaalsContact CG-O 3.22Å; R159-A408 WeakPolarHBondContact CG-O 3.08Å
160	N	90	Very high	87.8	Confident	45 Å²	45	50.7 Å²	50.7	24%	0.241	26%	0.263	C	S	.	.	H	α-helix	trans	-99.1	1.1	-171	-67.6	-78.2	0	0	0	114.3	F156 V410 V412	F156-N160 VanDerWaalsContact CD2-ND2 3.35Å; F156-N160 WeakPolarHBondContact CD2-ND2 3.45Å; F156-N160 WeakPolarHBondContact CE2-ND2 3.46Å; F156-N160 WeakPolarHBondContact O-CB 3.05Å; F156-N160 PolarHBondContact O-N 3.05Å; F156-N160 PolarHBondContact O-ND2 3.17Å; N160-V410 PolarHBondContact ND2-O 3.21Å; N160-V412 WeakPolarHBondContact OD1-CB 3.35Å; N160-V412 WeakPolarHBondContact OD1-CG2 3.46Å; N160-V412 PolarHBondContact OD1-N 2.83Å
161	T	88.9	Confident	87.6	Confident	54 Å²	54	54.5 Å²	54.5	33%	0.331	28%	0.283	S	S	.	.	S	Bend	trans	-103.2	107	172.6	-53.3	0	0	0	0	108.9	F157 V163 I164 S165	F157-T161 VanDerWaalsContact O-CB 3.3Å; F157-T161 WeakPolarHBondContact O-CB 3.26Å; F157-T161 PolarHBondContact O-N 2.95Å; F157-T161 VanDerWaalsContact O-N 3.17Å; F157-T161 PolarHBondContact O-OG1 3.44Å; T161-V163 PolarHBondContact O-N 3.42Å; T161-I164 HydrophobicContact CG2-CB 4.23Å; T161-I164 HydrophobicContact CG2-CD1 3.75Å; T161-I164 HydrophobicContact CG2-CG1 3.82Å; T161-I164 WeakPolarHBondContact O-CA 3.34Å; T161-I164 PolarHBondContact O-N 2.84Å; T161-S165 PolarHBondContact O-N 2.99Å
162	P	81.9	Confident	87.1	Confident	90 Å²	90	57.8 Å²	57.8	58%	0.584	30%	0.301	S	S	*	.	H	α-helix	trans	-52.5	-51.5	-168.3	-29.7	35.7	0	0	0	114.1	I164 S165 D166	P162-I164 PolarHBondContact O-N 2.9Å; P162-I164 VanDerWaalsContact O-N 3.1Å; P162-S165 PolarHBondContact O-N 3.2Å; P162-S165 VanDerWaalsContact O-N 3.09Å; P162-D166 VanDerWaalsContact O-CG 3.31Å; P162-D166 PolarHBondContact O-N 3.38Å
163	V	83.1	Confident	86.9	Confident	105 Å²	105	67.9 Å²	67.9	64%	0.636	34%	0.339	S	S	*	.	H	α-helix	trans	-55.6	-32.6	178.5	-176.2	0	0	0	0	112.8	T161 I167	T161-V163 PolarHBondContact O-N 3.42Å; V163-I167 WeakPolarHBondContact O-CD1 3.33Å; V163-I167 VanDerWaalsContact O-CG1 3.29Å; V163-I167 WeakPolarHBondContact O-CG1 3.45Å
164	I	83.7	Confident	86.7	Confident	58 Å²	58	73.4 Å²	73.4	30%	0.297	36%	0.358	S	S	.	.	H	α-helix	trans	-84.6	-40.1	-179.6	-61.9	-180	0	0	0	110.4	I158 T161 P162 I167 I168	I158-I164 HydrophobicContact CB-CG2 4.38Å; I158-I164 HydrophobicContact CG1-CG2 4.27Å; I158-I164 HydrophobicContact CG2-CG2 4.31Å; T161-I164 HydrophobicContact CG2-CB 4.23Å; T161-I164 HydrophobicContact CG2-CD1 3.75Å; T161-I164 HydrophobicContact CG2-CG1 3.82Å; T161-I164 WeakPolarHBondContact O-CA 3.34Å; T161-I164 PolarHBondContact O-N 2.84Å; P162-I164 PolarHBondContact O-N 2.9Å; P162-I164 VanDerWaalsContact O-N 3.1Å; I164-I167 PolarHBondContact O-N 3.42Å; I164-I168 HydrophobicContact CG2-CD1 3.59Å; I164-I168 HydrophobicContact CG2-CG1 4.45Å; I164-I168 WeakPolarHBondContact O-CB 3.46Å; I164-I168 WeakPolarHBondContact O-CG1 3.5Å; I164-I168 PolarHBondContact O-N 3.17Å
165	S	81.4	Confident	86.5	Confident	31 Å²	31	73.4 Å²	73.4	22%	0.217	36%	0.358	C	S	.	.	H	α-helix	trans	-68.7	-31.3	179.3	-169.2	0	0	0	0	113.2	I158 T161 P162 I167	I158-S165 PolarHBondContact O-N 3.37Å; T161-S165 PolarHBondContact O-N 2.99Å; P162-S165 PolarHBondContact O-N 3.2Å; P162-S165 VanDerWaalsContact O-N 3.09Å; S165-I167 VanDerWaalsContact C-N 3.31Å
166	D	79.1	Confident	86.3	Confident	118 Å²	118	74.2 Å²	74.2	63%	0.631	37%	0.365	S	S	*	.	H	α-helix	trans	-68.5	-34	175.7	-66.8	-25.6	0	0	0	111.5	P162	P162-D166 VanDerWaalsContact O-CG 3.31Å; P162-D166 PolarHBondContact O-N 3.38Å
167	I	82.1	Confident	86.3	Confident	74 Å²	74	73.7 Å²	73.7	38%	0.379	37%	0.367	S	S	.	.	H	α-helix	trans	-80.9	-31.5	178.8	-66.6	172.8	0	0	0	112	P113 G114 F118 V163 I164 S165	P113-I167 HydrophobicContact CB-CG2 3.98Å; G114-I167 WeakPolarHBondContact CA-O 3.21Å; G114-I167 PolarHBondContact N-O 2.84Å; F118-I167 HydrophobicContact CE1-CG2 3.8Å; F118-I167 HydrophobicContact CZ-CG2 4.48Å; V163-I167 WeakPolarHBondContact O-CD1 3.33Å; V163-I167 VanDerWaalsContact O-CG1 3.29Å; V163-I167 WeakPolarHBondContact O-CG1 3.45Å; I164-I167 PolarHBondContact O-N 3.42Å; S165-I167 VanDerWaalsContact C-N 3.31Å
168	I	82.9	Confident	86.3	Confident	12 Å²	12	69.5 Å²	69.5	6%	0.062	35%	0.35	C	S	.	.			trans	-105.3	86.5	-174.9	-65.9	173.2	0	0	0	109.9	F118 F122 I158 I164 I170	F118-I168 HydrophobicContact CE1-CG1 4.13Å; F122-I168 HydrophobicContact CB-CD1 4.08Å; F122-I168 HydrophobicContact CD1-CD1 3.16Å; F122-I168 HydrophobicContact CD1-CG1 4.4Å; F122-I168 HydrophobicContact CD2-CD1 4.15Å; F122-I168 HydrophobicContact CE1-CD1 3.5Å; F122-I168 VanDerWaalsContact CE1-CD1 3.5Å; F122-I168 HydrophobicContact CE2-CD1 4.41Å; F122-I168 HydrophobicContact CG-CD1 3.53Å; F122-I168 HydrophobicContact CG-CG1 4.39Å; F122-I168 HydrophobicContact CZ-CD1 4.11Å; I158-I168 HydrophobicContact CG1-CD1 4.33Å; I158-I168 HydrophobicContact CG2-CB 4.08Å; I158-I168 HydrophobicContact CG2-CD1 3.99Å; I158-I168 HydrophobicContact CG2-CG2 3.69Å; I164-I168 HydrophobicContact CG2-CD1 3.59Å; I164-I168 HydrophobicContact CG2-CG1 4.45Å; I164-I168 WeakPolarHBondContact O-CB 3.46Å; I164-I168 WeakPolarHBondContact O-CG1 3.5Å; I164-I168 PolarHBondContact O-N 3.17Å; I168-I170 HydrophobicContact CG2-CD1 4.09Å; I168-I170 HydrophobicContact CG2-CG1 4.03Å
169	Q	79.4	Confident	86.3	Confident	121 Å²	121	69.4 Å²	69.4	57%	0.565	35%	0.349	S	S	*	.			trans	-91.8	123.7	170.3	-57.4	-163.5	10.3	0	0	109.5
170	I	84.8	Confident	86.2	Confident	40 Å²	40	64.5 Å²	64.5	21%	0.205	33%	0.332	C	S	.	.			trans	-119.5	121.1	175.9	-58.3	178.8	0	0	0	107.4	I120 L123 I168 L172 L405	I120-I170 HydrophobicContact CG1-CG2 4.02Å; L123-I170 HydrophobicContact CB-CD1 4.03Å; L123-I170 HydrophobicContact CD1-CD1 3.5Å; L123-I170 VanDerWaalsContact CD1-CD1 3.5Å; L123-I170 HydrophobicContact CG-CD1 4.38Å; I168-I170 HydrophobicContact CG2-CD1 4.09Å; I168-I170 HydrophobicContact CG2-CG1 4.03Å; I170-L172 PolarHBondContact O-N 3.38Å; I170-L405 HydrophobicContact CD1-CD2 4.19Å; I170-L405 HydrophobicContact CG2-CD2 4.11Å
171	N	85.9	Confident	86.4	Confident	81 Å²	81	64.1 Å²	64.1	43%	0.433	33%	0.329	S	S	.	.			trans	-69.2	130.9	179.6	-172.9	-72.8	0	0	0	110.6	N116 R173 W174 S175	N116-N171 WeakPolarHBondContact OD1-CB 3.37Å; N116-N171 PolarHBondContact OD1-N 3.13Å; N171-R173 PolarHBondContact O-N 3.02Å; N171-R173 VanDerWaalsContact O-N 3.14Å; N171-R173 WeakPolarHBondContact OD1-CB 3.44Å; N171-R173 PolarHBondContact OD1-N 2.85Å; N171-W174 PolarHBondContact O-N 2.95Å; N171-S175 PolarHBondContact O-N 3.45Å
172	L	84.7	Confident	86.5	Confident	87 Å²	87	61.6 Å²	61.6	46%	0.455	31%	0.314	S	S	.	.	H	α-helix	trans	-55.3	-34.4	-177.3	-64.1	175.9	0	0	0	113.2	I170 S175 A176	I170-L172 PolarHBondContact O-N 3.38Å; L172-S175 PolarHBondContact O-N 3.28Å; L172-A176 WeakPolarHBondContact O-CB 3.48Å; L172-A176 PolarHBondContact O-N 2.96Å
173	R	87.8	Confident	86.8	Confident	213 Å²	213	57.4 Å²	57.4	80%	0.804	29%	0.286	S	S	*	.	H	α-helix	trans	-67.1	-42.9	178	-61.7	-177.4	177.8	-179.9	-0.6	112.1	N171 A177	N171-R173 PolarHBondContact O-N 3.02Å; N171-R173 VanDerWaalsContact O-N 3.14Å; N171-R173 WeakPolarHBondContact OD1-CB 3.44Å; N171-R173 PolarHBondContact OD1-N 2.85Å; R173-A177 WeakPolarHBondContact O-CB 3.49Å; R173-A177 PolarHBondContact O-N 3Å
174	W	89.9	Confident	87.3	Confident	142 Å²	142	52.4 Å²	52.4	54%	0.538	26%	0.256	S	S	.	.	H	α-helix	trans	-69.4	-38.5	176.2	-78.1	103.6	0	0	0	111.7	I120 N171 A177 L178	I120-W174 HydrophobicContact CD1-CB 3.79Å; I120-W174 HydrophobicContact CD1-CG 4.2Å; N171-W174 PolarHBondContact O-N 2.95Å; W174-A177 PolarHBondContact O-N 3.25Å; W174-L178 WeakPolarHBondContact O-CB 3.29Å; W174-L178 WeakPolarHBondContact O-CG 3.35Å; W174-L178 PolarHBondContact O-N 3.36Å
175	S	90.2	Very high	87.7	Confident	5 Å²	5	49.9 Å²	49.9	4%	0.035	24%	0.243	C	C	.	.	H	α-helix	trans	-57	-55.2	172.6	-172.5	0	0	0	0	111.4	N171 L172 A177 L178 R179	N171-S175 PolarHBondContact O-N 3.45Å; L172-S175 PolarHBondContact O-N 3.28Å; S175-A177 VanDerWaalsContact C-N 3.35Å; S175-A177 PolarHBondContact O-N 2.85Å; S175-L178 PolarHBondContact O-N 3.05Å; S175-R179 WeakPolarHBondContact O-CG 3.32Å; S175-R179 PolarHBondContact O-N 3.17Å; S175-R179 PolarHBondContact OG-NH1 2.82Å
176	A	88.9	Confident	88.1	Confident	17 Å²	17	49.5 Å²	49.5	14%	0.14	24%	0.238	C	C	.	.	H	α-helix	trans	-60.4	-39.9	177.6	0	0	0	0	0	112.7	L172 R179 N180 D475	L172-A176 WeakPolarHBondContact O-CB 3.48Å; L172-A176 PolarHBondContact O-N 2.96Å; A176-R179 PolarHBondContact O-N 3.4Å; A176-N180 WeakPolarHBondContact O-CB 3.43Å; A176-N180 PolarHBondContact O-N 2.97Å; A176-N180 PolarHBondContact O-ND2 3.37Å; A176-N180 VanDerWaalsContact O-ND2 3.11Å; A176-D475 HydrophobicContact CB-CB 4.21Å
177	A	91.9	Very high	88.5	Confident	29 Å²	29	44 Å²	44	24%	0.24	21%	0.209	C	C	.	.	H	α-helix	trans	-63	-46.8	176.3	0	0	0	0	0	112.3	R173 W174 S175 R179 N180 I181 F354	R173-A177 WeakPolarHBondContact O-CB 3.49Å; R173-A177 PolarHBondContact O-N 3Å; W174-A177 PolarHBondContact O-N 3.25Å; S175-A177 VanDerWaalsContact C-N 3.35Å; S175-A177 PolarHBondContact O-N 2.85Å; A177-R179 PolarHBondContact O-N 3.16Å; A177-N180 PolarHBondContact O-N 3.25Å; A177-I181 WeakPolarHBondContact O-CG1 3.3Å; A177-I181 PolarHBondContact O-N 2.85Å; A177-F354 HydrophobicContact CB-CE1 4.39Å; A177-F354 HydrophobicContact CB-CZ 4.39Å
178	L	93.2	Very high	88.9	Confident	21 Å²	21	40.5 Å²	40.5	11%	0.11	19%	0.191	C	C	.	.	H	α-helix	trans	-64.9	-38.3	177.8	-72	165.6	0	0	0	112	I120 W174 S175 A182 F398 F401 L405	I120-L178 HydrophobicContact CD1-CD1 4.28Å; I120-L178 HydrophobicContact CG1-CD1 4.36Å; I120-L178 HydrophobicContact CG2-CD1 3.76Å; W174-L178 WeakPolarHBondContact O-CB 3.29Å; W174-L178 WeakPolarHBondContact O-CG 3.35Å; W174-L178 PolarHBondContact O-N 3.36Å; S175-L178 PolarHBondContact O-N 3.05Å; L178-A182 PolarHBondContact O-N 3.26Å; L178-A182 VanDerWaalsContact O-N 3.08Å; L178-F398 HydrophobicContact CD2-CE1 4.18Å; L178-F401 HydrophobicContact CB-CB 4.46Å; L178-F401 HydrophobicContact CD1-CD1 4.05Å; L178-F401 HydrophobicContact CD1-CE1 4.23Å; L178-F401 HydrophobicContact CD2-CD1 4.45Å; L178-F401 HydrophobicContact CD2-CD2 4.37Å; L178-F401 HydrophobicContact CD2-CE2 4.5Å; L178-F401 HydrophobicContact CD2-CG 4.36Å; L178-L405 HydrophobicContact CB-CD1 3.56Å; L178-L405 HydrophobicContact CD1-CD1 4.14Å
179	R	91.3	Very high	89.1	Confident	2 Å²	2	45 Å²	45	1%	0.008	21%	0.207	C	C	.	.	H	α-helix	trans	-61.7	-46.1	171.6	-72.6	-165.3	-70.9	-109.4	4.5	112.2	S175 A176 A177 I181 A182 L183 L402 L405 E409 S471 D475	S175-R179 WeakPolarHBondContact O-CG 3.32Å; S175-R179 PolarHBondContact O-N 3.17Å; S175-R179 PolarHBondContact OG-NH1 2.82Å; A176-R179 PolarHBondContact O-N 3.4Å; A177-R179 PolarHBondContact O-N 3.16Å; R179-I181 PolarHBondContact O-N 3.12Å; R179-A182 PolarHBondContact O-N 2.95Å; R179-L183 WeakPolarHBondContact O-CB 3.43Å; R179-L183 PolarHBondContact O-N 3.01Å; R179-L402 HydrophobicContact CB-CD1 4.33Å; R179-L402 HydrophobicContact CG-CD1 4.32Å; R179-L405 HydrophobicContact CG-CB 4.16Å; R179-L405 HydrophobicContact CG-CD1 4.21Å; R179-E409 IonicContact CZ-OE1 2.77Å; R179-E409 VanDerWaalsContact CZ-OE1 3.26Å; R179-E409 IonicContact NH1-OE1 3.47Å; R179-E409 PolarHBondContact NH1-OE1 2.93Å; R179-E409 IonicContact NH2-OE1 3.62Å; R179-E409 PolarHBondContact NH2-OE1 2.74Å; R179-S471 WeakPolarHBondContact CD-OG 3.37Å; R179-D475 IonicContact CZ-OD1 2.88Å; R179-D475 IonicContact CZ-OD2 3.42Å; R179-D475 IonicContact NE-OD2 3.25Å; R179-D475 PolarHBondContact NE-OD2 2.99Å; R179-D475 VanDerWaalsContact NH2-CG 3.31Å; R179-D475 IonicContact NH2-OD1 3.05Å; R179-D475 PolarHBondContact NH2-OD1 3.17Å; R179-D475 IonicContact NH2-OD2 2.87Å; R179-D475 PolarHBondContact NH2-OD2 2.97Å; R179-D475 VanDerWaalsContact NH2-OD2 3.11Å
180	N	89.6	Confident	89.3	Confident	10 Å²	10	40.8 Å²	40.8	5%	0.053	19%	0.193	C	C	.	.	H	α-helix	trans	-67.8	-33.2	-180	-78.8	-40.3	0	0	0	113.4	A176 A177 S184 V353 F354	A176-N180 WeakPolarHBondContact O-CB 3.43Å; A176-N180 PolarHBondContact O-N 2.97Å; A176-N180 PolarHBondContact O-ND2 3.37Å; A176-N180 VanDerWaalsContact O-ND2 3.11Å; A177-N180 PolarHBondContact O-N 3.25Å; N180-S184 WeakPolarHBondContact O-CB 3.23Å; N180-S184 PolarHBondContact O-N 2.91Å; N180-V353 HydrophobicContact CB-CG1 4Å; N180-F354 HydrophobicContact CB-CE1 3.99Å; N180-F354 HydrophobicContact CB-CE2 4.49Å; N180-F354 HydrophobicContact CB-CZ 3.82Å
181	I	93.8	Very high	89.4	Confident	37 Å²	37	38.9 Å²	38.9	19%	0.19	18%	0.183	C	C	.	.	H	α-helix	trans	-63.6	-47.5	169.4	-66.4	162.5	0	0	0	110.2	A177 R179 L183 S184 I185 M350 F354 F398	A177-I181 WeakPolarHBondContact O-CG1 3.3Å; A177-I181 PolarHBondContact O-N 2.85Å; R179-I181 PolarHBondContact O-N 3.12Å; I181-L183 PolarHBondContact O-N 3.47Å; I181-S184 WeakPolarHBondContact O-CB 3.19Å; I181-S184 PolarHBondContact O-N 2.99Å; I181-I185 HydrophobicContact CG2-CD1 3.81Å; I181-I185 WeakPolarHBondContact O-CG1 3.44Å; I181-I185 PolarHBondContact O-N 2.86Å; I181-M350 HydrophobicContact CG1-SD 4.29Å; I181-M350 HydrophobicContact CG2-SD 3.85Å; I181-F354 HydrophobicContact CG1-CE2 3.78Å; I181-F354 HydrophobicContact CG1-CZ 3.94Å; I181-F398 HydrophobicContact CB-CD1 4.24Å; I181-F398 HydrophobicContact CB-CE1 4.03Å; I181-F398 HydrophobicContact CD1-CE1 4.36Å; I181-F398 HydrophobicContact CG2-CD1 3.65Å; I181-F398 HydrophobicContact CG2-CD2 4.34Å; I181-F398 HydrophobicContact CG2-CE1 3.38Å; I181-F398 HydrophobicContact CG2-CE2 4.11Å; I181-F398 HydrophobicContact CG2-CG 4.13Å; I181-F398 HydrophobicContact CG2-CZ 3.63Å
182	A	92	Very high	89.5	Confident	0 Å²	0	35 Å²	35	0%	0	16%	0.163	C	C	.	.	H	α-helix	trans	-64.4	-40.6	179.2	0	0	0	0	0	112.7	L178 R179 I185 I186 W395 F398 L402	L178-A182 PolarHBondContact O-N 3.26Å; L178-A182 VanDerWaalsContact O-N 3.08Å; R179-A182 PolarHBondContact O-N 2.95Å; A182-I185 PolarHBondContact O-N 3.44Å; A182-I186 WeakPolarHBondContact O-CG2 3.38Å; A182-I186 PolarHBondContact O-N 3.27Å; A182-W395 HydrophobicContact CB-CZ3 4.33Å; A182-F398 HydrophobicContact CB-CB 3.98Å; A182-L402 HydrophobicContact CB-CB 3.76Å; A182-L402 HydrophobicContact CB-CD1 4.16Å; A182-L402 HydrophobicContact CB-CG 4.37Å
183	L	88.1	Confident	89.3	Confident	2 Å²	2	33.1 Å²	33.1	1%	0.01	16%	0.164	C	C	.	.	H	α-helix	trans	-52.8	-51.8	169.5	171	73.4	0	0	0	110.7	R179 I181 I185 I186 L187 V353 A468 I469 L472	R179-L183 WeakPolarHBondContact O-CB 3.43Å; R179-L183 PolarHBondContact O-N 3.01Å; I181-L183 PolarHBondContact O-N 3.47Å; L183-I185 VanDerWaalsContact C-N 3.31Å; L183-I185 PolarHBondContact O-N 3.27Å; L183-I186 VanDerWaalsContact O-CG2 3.26Å; L183-I186 WeakPolarHBondContact O-CG2 3.49Å; L183-I186 PolarHBondContact O-N 3.26Å; L183-L187 HydrophobicContact CD1-CD1 3.66Å; L183-L187 HydrophobicContact CD1-CG 4.02Å; L183-L187 HydrophobicContact CG-CD1 3.83Å; L183-L187 HydrophobicContact CG-CG 4.42Å; L183-L187 WeakPolarHBondContact O-CB 3.42Å; L183-L187 VanDerWaalsContact O-CG 3.24Å; L183-L187 WeakPolarHBondContact O-CG 3.32Å; L183-L187 PolarHBondContact O-N 3.49Å; L183-V353 HydrophobicContact CD2-CG1 4.12Å; L183-A468 HydrophobicContact CD1-CB 3.75Å; L183-I469 HydrophobicContact CD1-CG2 4.07Å; L183-L472 HydrophobicContact CD2-CD2 3.96Å
184	S	91.9	Very high	88.7	Confident	0 Å²	0	23.5 Å²	23.5	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-59.2	-41.8	179.9	-173.3	0	0	0	0	112.4	N180 I181 T188 S349 M350 T369	N180-S184 WeakPolarHBondContact O-CB 3.23Å; N180-S184 PolarHBondContact O-N 2.91Å; I181-S184 WeakPolarHBondContact O-CB 3.19Å; I181-S184 PolarHBondContact O-N 2.99Å; S184-T188 VanDerWaalsContact O-CB 3.3Å; S184-T188 WeakPolarHBondContact O-CB 3.34Å; S184-T188 PolarHBondContact O-N 3.41Å; S184-T188 PolarHBondContact O-OG1 2.98Å; S184-S349 WeakPolarHBondContact OG-CB 3.42Å; S184-S349 PolarHBondContact OG-O 3.37Å; S184-M350 WeakPolarHBondContact OG-CA 3.49Å; S184-M350 PolarHBondContact OG-N 3.05Å; S184-T369 WeakPolarHBondContact O-CG2 3.43Å
185	I	93.1	Very high	87.9	Confident	5 Å²	5	20.4 Å²	20.4	3%	0.026	12%	0.122	C	C	.	.	H	α-helix	trans	-67.7	-43.1	177.7	-64.1	163.5	0	0	0	111.8	I181 A182 L183 T188 R189 L346 V391 A394 W395 F398	I181-I185 HydrophobicContact CG2-CD1 3.81Å; I181-I185 WeakPolarHBondContact O-CG1 3.44Å; I181-I185 PolarHBondContact O-N 2.86Å; A182-I185 PolarHBondContact O-N 3.44Å; L183-I185 VanDerWaalsContact C-N 3.31Å; L183-I185 PolarHBondContact O-N 3.27Å; I185-T188 WeakPolarHBondContact O-CB 3.29Å; I185-T188 PolarHBondContact O-N 2.95Å; I185-R189 WeakPolarHBondContact O-CB 3.25Å; I185-R189 PolarHBondContact O-N 3.44Å; I185-L346 HydrophobicContact CG1-CD2 4.06Å; I185-V391 HydrophobicContact CG2-CG1 4.37Å; I185-A394 HydrophobicContact CD1-CB 4.49Å; I185-A394 HydrophobicContact CG2-CB 4.34Å; I185-W395 HydrophobicContact CB-CE3 4.49Å; I185-W395 HydrophobicContact CG2-CB 3.85Å; I185-W395 HydrophobicContact CG2-CE3 4.13Å; I185-F398 HydrophobicContact CD1-CB 3.8Å; I185-F398 HydrophobicContact CD1-CD1 4.44Å; I185-F398 HydrophobicContact CD1-CD2 3.32Å; I185-F398 HydrophobicContact CD1-CE2 3.99Å; I185-F398 HydrophobicContact CD1-CG 3.59Å
186	I	88.6	Confident	87.1	Confident	23 Å²	23	21.9 Å²	21.9	12%	0.118	13%	0.132	C	C	.	.	H	α-helix	trans	-71.1	-37.5	179.7	-168.6	59.6	0	0	0	112.3	A182 L183 T188 R189 A190 W395 A468	A182-I186 WeakPolarHBondContact O-CG2 3.38Å; A182-I186 PolarHBondContact O-N 3.27Å; L183-I186 VanDerWaalsContact O-CG2 3.26Å; L183-I186 WeakPolarHBondContact O-CG2 3.49Å; L183-I186 PolarHBondContact O-N 3.26Å; I186-T188 VanDerWaalsContact C-N 3.35Å; I186-R189 HydrophobicContact CD1-CB 4.49Å; I186-R189 WeakPolarHBondContact O-CB 3.33Å; I186-R189 PolarHBondContact O-N 3.15Å; I186-A190 WeakPolarHBondContact O-CB 3.35Å; I186-A190 PolarHBondContact O-N 3.19Å; I186-W395 HydrophobicContact CB-CE3 3.92Å; I186-W395 HydrophobicContact CB-CH2 3.9Å; I186-W395 HydrophobicContact CB-CZ3 3.57Å; I186-W395 HydrophobicContact CD1-CD2 4.15Å; I186-W395 HydrophobicContact CD1-CE3 4.34Å; I186-W395 HydrophobicContact CD1-CH2 4.18Å; I186-W395 HydrophobicContact CD1-CZ2 4Å; I186-W395 HydrophobicContact CD1-CZ3 4.37Å; I186-W395 HydrophobicContact CG1-CH2 4.11Å; I186-W395 HydrophobicContact CG1-CZ2 4.4Å; I186-W395 HydrophobicContact CG1-CZ3 4.25Å; I186-W395 HydrophobicContact CG2-CH2 4.47Å; I186-W395 HydrophobicContact CG2-CZ3 4.2Å; I186-A468 HydrophobicContact CG2-CB 3.84Å
187	L	87.6	Confident	86.3	Confident	4 Å²	4	29 Å²	29	2%	0.021	16%	0.16	C	C	.	.	H	α-helix	trans	-66.1	-38.5	174.2	-68.4	178.1	0	0	0	111.6	L183 A190 G191 I285 T369	L183-L187 HydrophobicContact CD1-CD1 3.66Å; L183-L187 HydrophobicContact CD1-CG 4.02Å; L183-L187 HydrophobicContact CG-CD1 3.83Å; L183-L187 HydrophobicContact CG-CG 4.42Å; L183-L187 WeakPolarHBondContact O-CB 3.42Å; L183-L187 VanDerWaalsContact O-CG 3.24Å; L183-L187 WeakPolarHBondContact O-CG 3.32Å; L183-L187 PolarHBondContact O-N 3.49Å; L187-A190 PolarHBondContact O-N 2.96Å; L187-G191 PolarHBondContact O-N 2.77Å; L187-I285 HydrophobicContact CD2-CD1 3.51Å; L187-I285 HydrophobicContact CD2-CG1 4.23Å; L187-I285 HydrophobicContact CD2-CG2 4.02Å; L187-T369 HydrophobicContact CB-CG2 3.55Å
188	T	92	Very high	84.9	Confident	0 Å²	0	28.6 Å²	28.6	0%	0	16%	0.156	C	C	.	.	H	α-helix	trans	-58.5	-48.6	170.4	-64.4	0	0	0	0	111.1	S184 I185 I186 A190 G191 L192 V345 L346 S349 A373 V391	S184-T188 VanDerWaalsContact O-CB 3.3Å; S184-T188 WeakPolarHBondContact O-CB 3.34Å; S184-T188 PolarHBondContact O-N 3.41Å; S184-T188 PolarHBondContact O-OG1 2.98Å; I185-T188 WeakPolarHBondContact O-CB 3.29Å; I185-T188 PolarHBondContact O-N 2.95Å; I186-T188 VanDerWaalsContact C-N 3.35Å; T188-A190 VanDerWaalsContact C-N 3.33Å; T188-A190 PolarHBondContact O-N 3.23Å; T188-G191 PolarHBondContact O-N 2.88Å; T188-L192 HydrophobicContact CG2-CD1 4.09Å; T188-L192 WeakPolarHBondContact O-CG 3.46Å; T188-L192 PolarHBondContact O-N 3.44Å; T188-V345 HydrophobicContact CG2-CG1 3.33Å; T188-L346 HydrophobicContact CG2-CD2 4.15Å; T188-S349 VanDerWaalsContact OG1-CB 3.23Å; T188-S349 WeakPolarHBondContact OG1-CB 3.34Å; T188-S349 PolarHBondContact OG1-OG 2.92Å; T188-A373 HydrophobicContact CG2-CB 4.21Å; T188-A373 WeakPolarHBondContact O-CB 3.5Å; T188-V391 HydrophobicContact CG2-CG1 4.07Å; T188-V391 HydrophobicContact CG2-CG2 4.08Å
189	R	87.4	Confident	83.6	Confident	107 Å²	107	31.4 Å²	31.4	40%	0.404	17%	0.171	S	C	.	.	H	α-helix	trans	-62.2	-40.1	178.8	-173.4	-179.7	175.1	-169.2	-2.2	112	I185 I186 G193 V391	I185-R189 WeakPolarHBondContact O-CB 3.25Å; I185-R189 PolarHBondContact O-N 3.44Å; I186-R189 HydrophobicContact CD1-CB 4.49Å; I186-R189 WeakPolarHBondContact O-CB 3.33Å; I186-R189 PolarHBondContact O-N 3.15Å; R189-G193 PolarHBondContact O-N 3.44Å; R189-V391 HydrophobicContact CB-CG1 3.87Å; R189-V391 HydrophobicContact CG-CG1 4.46Å
190	A	83.3	Confident	82.6	Confident	32 Å²	32	39.6 Å²	39.6	26%	0.264	21%	0.207	S	C	.	.	H	α-helix	trans	-63.9	-48.8	175.9	0	0	0	0	0	111.1	I186 L187 T188 L192 G193 L194	I186-A190 WeakPolarHBondContact O-CB 3.35Å; I186-A190 PolarHBondContact O-N 3.19Å; L187-A190 PolarHBondContact O-N 2.96Å; T188-A190 VanDerWaalsContact C-N 3.33Å; T188-A190 PolarHBondContact O-N 3.23Å; A190-L192 PolarHBondContact O-N 3.24Å; A190-G193 PolarHBondContact O-N 3.12Å; A190-L194 WeakPolarHBondContact O-CG 3.24Å; A190-L194 PolarHBondContact O-N 3.37Å
191	G	87	Confident	81.4	Confident	0 Å²	0	47.7 Å²	47.7	0%	0	24%	0.242	C	C	.	.	H	α-helix	trans	-60	-42.2	177.7	0	0	0	0	0	113.3	L187 T188 F374	L187-G191 PolarHBondContact O-N 2.77Å; T188-G191 PolarHBondContact O-N 2.88Å; G191-F374 VanDerWaalsContact O-CA 3.3Å; G191-F374 WeakPolarHBondContact O-CA 3.19Å
192	L	88.1	Confident	79.8	Confident	0 Å²	0	49 Å²	49	0%	0	25%	0.248	C	C	.	.	H	α-helix	trans	-63.1	-48.8	172.9	-71	169.9	0	0	0	111.5	T188 A190 L194 A373 W380 K384 V387 E388 V391	T188-L192 HydrophobicContact CG2-CD1 4.09Å; T188-L192 WeakPolarHBondContact O-CG 3.46Å; T188-L192 PolarHBondContact O-N 3.44Å; A190-L192 PolarHBondContact O-N 3.24Å; L192-L194 PolarHBondContact O-N 3.3Å; L192-A373 HydrophobicContact CG-CB 4.26Å; L192-W380 HydrophobicContact CD2-CZ3 4.06Å; L192-K384 WeakPolarHBondContact O-CE 3.18Å; L192-K384 PolarHBondContact O-NZ 2.9Å; L192-V387 HydrophobicContact CD1-CG1 3.85Å; L192-V387 HydrophobicContact CD2-CG1 4.39Å; L192-E388 HydrophobicContact CB-CG 3.8Å; L192-E388 HydrophobicContact CD1-CG 4.15Å; L192-E388 HydrophobicContact CG-CG 4.49Å; L192-V391 HydrophobicContact CD1-CB 4.37Å; L192-V391 HydrophobicContact CD1-CG2 3.9Å
193	G	78.9	Confident	78.8	Confident	47 Å²	47	56.6 Å²	56.6	49%	0.485	28%	0.282	S	S	.	.	H	α-helix	trans	-62.5	-9.3	-174.7	0	0	0	0	0	116.1	R189 A190	R189-G193 PolarHBondContact O-N 3.44Å; A190-G193 PolarHBondContact O-N 3.12Å
194	L	76.1	Confident	78.4	Confident	11 Å²	11	59.6 Å²	59.6	6%	0.058	31%	0.307	C	S	.	.			trans	-69.4	128	175.1	-66.4	163.8	0	0	0	111.8	A190 L192 P196 I282 L370 F374 K384	A190-L194 WeakPolarHBondContact O-CG 3.24Å; A190-L194 PolarHBondContact O-N 3.37Å; L192-L194 PolarHBondContact O-N 3.3Å; L194-P196 WeakPolarHBondContact O-CD 3.42Å; L194-I282 HydrophobicContact CD1-CD1 3.74Å; L194-I282 HydrophobicContact CD1-CG1 4.42Å; L194-I282 HydrophobicContact CD2-CD1 3.64Å; L194-I282 HydrophobicContact CG-CD1 4.34Å; L194-L370 HydrophobicContact CD1-CD2 4.4Å; L194-F374 HydrophobicContact CB-CD2 3.64Å; L194-F374 HydrophobicContact CB-CE2 3.83Å; L194-F374 HydrophobicContact CD1-CB 4.17Å; L194-F374 HydrophobicContact CD1-CD2 3.71Å; L194-F374 HydrophobicContact CD1-CE2 4.34Å; L194-F374 HydrophobicContact CD1-CG 4.04Å; L194-F374 HydrophobicContact CG-CD2 4.34Å; L194-K384 PolarHBondContact O-NZ 3Å
195	D	72.3	Confident	78	Confident	76 Å²	76	61.9 Å²	61.9	41%	0.406	32%	0.32	S	S	.	.			trans	-94.6	112.6	169.8	174.8	24.9	0	0	0	111.5	K197 A198 L199	D195-K197 PolarHBondContact O-N 3.21Å; D195-K197 WeakPolarHBondContact OD1-CB 3.43Å; D195-K197 PolarHBondContact OD1-N 2.86Å; D195-A198 HydrophobicContact CB-CB 4Å; D195-A198 PolarHBondContact O-N 3.37Å; D195-A198 WeakPolarHBondContact OD2-CB 3.29Å; D195-A198 PolarHBondContact OD2-N 3.41Å; D195-L199 WeakPolarHBondContact O-CB 3.28Å; D195-L199 PolarHBondContact O-N 3.36Å; D195-L199 VanDerWaalsContact O-N 3.1Å
196	P	73.1	Confident	77.5	Confident	36 Å²	36	61.8 Å²	61.8	23%	0.234	32%	0.32	C	S	.	.	H	α-helix	trans	-64.7	-22	175.8	30.6	-39.1	0	0	0	113.5	L194 K200 F374 V378	L194-P196 WeakPolarHBondContact O-CD 3.42Å; P196-K200 WeakPolarHBondContact O-CG 3.48Å; P196-K200 PolarHBondContact O-N 2.99Å; P196-F374 HydrophobicContact CB-CE2 4.47Å; P196-F374 HydrophobicContact CB-CZ 4.42Å; P196-V378 HydrophobicContact CB-CG2 4.18Å; P196-V378 HydrophobicContact CG-CG2 4.04Å
197	K	72.5	Confident	77.4	Confident	167 Å²	167	65 Å²	65	73%	0.726	34%	0.337	S	S	*	.	H	α-helix	trans	-76.2	-49.3	178.4	-62.5	178	-179.8	175.9	0	110.5	D195 L199 K200 K201	D195-K197 PolarHBondContact O-N 3.21Å; D195-K197 WeakPolarHBondContact OD1-CB 3.43Å; D195-K197 PolarHBondContact OD1-N 2.86Å; K197-L199 VanDerWaalsContact C-N 3.3Å; K197-L199 PolarHBondContact O-N 2.77Å; K197-K200 PolarHBondContact O-N 2.83Å; K197-K201 WeakPolarHBondContact O-CB 3.18Å; K197-K201 PolarHBondContact O-N 3.15Å
198	A	63.1	Low	77.5	Confident	21 Å²	21	69.5 Å²	69.5	17%	0.174	35%	0.354	C	S	.	.	H	α-helix	trans	-55.8	-43.7	171.4	0	0	0	0	0	112	D195 K200 K201 L202	D195-A198 HydrophobicContact CB-CB 4Å; D195-A198 PolarHBondContact O-N 3.37Å; D195-A198 WeakPolarHBondContact OD2-CB 3.29Å; D195-A198 PolarHBondContact OD2-N 3.41Å; A198-K200 VanDerWaalsContact C-N 3.31Å; A198-K200 PolarHBondContact O-N 3.39Å; A198-K201 PolarHBondContact O-N 3.28Å; A198-L202 PolarHBondContact O-N 2.7Å
199	L	66.4	Low	77.4	Confident	80 Å²	80	69.5 Å²	69.5	42%	0.419	35%	0.354	S	S	.	.	H	α-helix	trans	-56.8	-42.7	178.2	-150.9	80.3	0	0	0	112.2	D195 K197 I279	D195-L199 WeakPolarHBondContact O-CB 3.28Å; D195-L199 PolarHBondContact O-N 3.36Å; D195-L199 VanDerWaalsContact O-N 3.1Å; K197-L199 VanDerWaalsContact C-N 3.3Å; K197-L199 PolarHBondContact O-N 2.77Å; L199-I279 HydrophobicContact CD1-CD1 3.52Å; L199-I279 HydrophobicContact CD1-CG1 3.66Å
200	K	70	Confident	77.4	Confident	174 Å²	174	64.4 Å²	64.4	76%	0.757	34%	0.335	S	S	*	.	H	α-helix	trans	-73.4	-38.6	176.1	-72.6	177.9	179.7	-177.7	0	112.9	P196 K197 A198	P196-K200 WeakPolarHBondContact O-CG 3.48Å; P196-K200 PolarHBondContact O-N 2.99Å; K197-K200 PolarHBondContact O-N 2.83Å; A198-K200 VanDerWaalsContact C-N 3.31Å; A198-K200 PolarHBondContact O-N 3.39Å
201	K	64.1	Low	77.8	Confident	180 Å²	180	66.7 Å²	66.7	78%	0.783	34%	0.339	S	S	*	.	H	α-helix	trans	-76	-35.6	-171.8	-167.7	174.2	-179.3	-179.9	0	113.6	K197 A198	K197-K201 WeakPolarHBondContact O-CB 3.18Å; K197-K201 PolarHBondContact O-N 3.15Å; A198-K201 PolarHBondContact O-N 3.28Å
202	L	60.5	Low	78.1	Confident	63 Å²	63	67.5 Å²	67.5	33%	0.33	35%	0.347	S	S	.	.	T	Hydrogen-bonded Turn	trans	-104.4	19.3	-172.6	-61.7	175.6	0	0	0	114.3	A198 A204 V205 C206	A198-L202 PolarHBondContact O-N 2.7Å; L202-A204 VanDerWaalsContact C-N 3.34Å; L202-A204 PolarHBondContact O-N 2.84Å; L202-V205 PolarHBondContact O-N 3.42Å; L202-C206 HydrophobicContact CB-CB 3.83Å; L202-C206 WeakPolarHBondContact O-CB 3.36Å; L202-C206 PolarHBondContact O-N 2.67Å
203	K	70.7	Confident	78.5	Confident	161 Å²	161	67.5 Å²	67.5	70%	0.7	35%	0.347	S	S	*	.	H	α-helix	trans	-46.5	-37.9	-162.6	66.3	-176.6	-179.8	-179.7	0	117.6	L207	K203-L207 WeakPolarHBondContact O-CB 3.43Å
204	A	80.5	Confident	79.2	Confident	65 Å²	65	65.3 Å²	65.3	54%	0.537	32%	0.324	S	S	.	.	H	α-helix	trans	-85.1	-52.5	-173.4	0	0	0	0	0	113.2	L202 R208	L202-A204 VanDerWaalsContact C-N 3.34Å; L202-A204 PolarHBondContact O-N 2.84Å; A204-R208 WeakPolarHBondContact O-CB 3.43Å; A204-R208 WeakPolarHBondContact O-CD 3.2Å; A204-R208 VanDerWaalsContact O-CG 3.29Å; A204-R208 WeakPolarHBondContact O-CG 3.36Å; A204-R208 PolarHBondContact O-N 3.14Å
205	V	82	Confident	80.2	Confident	47 Å²	47	68.4 Å²	68.4	29%	0.285	34%	0.34	S	S	.	.	H	α-helix	trans	-72.5	-43.3	-178.2	176.7	0	0	0	0	110.7	L202 L207 R208 L209 L272 A445	L202-V205 PolarHBondContact O-N 3.42Å; V205-L207 PolarHBondContact O-N 2.92Å; V205-R208 PolarHBondContact O-N 2.65Å; V205-L209 VanDerWaalsContact O-CB 3.27Å; V205-L209 WeakPolarHBondContact O-CB 3.4Å; V205-L209 PolarHBondContact O-N 3.5Å; V205-L272 HydrophobicContact CG1-CD1 4.2Å; V205-L272 HydrophobicContact CG1-CD2 3.85Å; V205-A445 HydrophobicContact CB-CB 4.32Å; V205-A445 HydrophobicContact CG1-CB 3.54Å; V205-A445 HydrophobicContact CG2-CB 3.74Å
206	C	83.5	Confident	81.3	Confident	3 Å²	3	66.2 Å²	66.2	2%	0.02	33%	0.331	C	S	.	.	H	α-helix	trans	-61.2	-46.8	179.6	-166.1	0	0	0	0	111.2	L202 L209 S210 L272 A276 I279	L202-C206 HydrophobicContact CB-CB 3.83Å; L202-C206 WeakPolarHBondContact O-CB 3.36Å; L202-C206 PolarHBondContact O-N 2.67Å; C206-L209 PolarHBondContact O-N 2.9Å; C206-S210 WeakPolarHBondContact O-CB 3.06Å; C206-S210 PolarHBondContact O-N 3.34Å; C206-S210 PolarHBondContact O-OG 2.91Å; C206-L272 HydrophobicContact CB-CD1 3.96Å; C206-A276 VanDerWaalsContact SG-CA 3.54Å; C206-I279 VanDerWaalsContact SG-CD1 3.55Å
207	L	86.5	Confident	82.4	Confident	90 Å²	90	64.5 Å²	64.5	47%	0.471	32%	0.32	S	S	.	.	H	α-helix	trans	-64.7	-43.3	178.6	-168	76.1	0	0	0	112.5	K203 V205 L209 S210 F211	K203-L207 WeakPolarHBondContact O-CB 3.43Å; V205-L207 PolarHBondContact O-N 2.92Å; L207-L209 PolarHBondContact O-N 3.2Å; L207-S210 PolarHBondContact O-N 3.43Å; L207-F211 HydrophobicContact CD1-CD2 3.55Å; L207-F211 HydrophobicContact CD1-CE2 3.34Å; L207-F211 HydrophobicContact CD1-CZ 4.19Å; L207-F211 HydrophobicContact CG-CD2 3.97Å; L207-F211 HydrophobicContact CG-CE2 4.24Å; L207-F211 WeakPolarHBondContact O-CB 3.39Å; L207-F211 PolarHBondContact O-N 3.41Å
208	R	89.3	Confident	83.5	Confident	99 Å²	99	56.7 Å²	56.7	37%	0.374	29%	0.286	S	S	.	.	H	α-helix	trans	-59.7	-45.4	174.5	-78.8	169.4	51.8	138.7	4.3	112.4	A204 V205 S210 G212 M441	A204-R208 WeakPolarHBondContact O-CB 3.43Å; A204-R208 WeakPolarHBondContact O-CD 3.2Å; A204-R208 VanDerWaalsContact O-CG 3.29Å; A204-R208 WeakPolarHBondContact O-CG 3.36Å; A204-R208 PolarHBondContact O-N 3.14Å; V205-R208 PolarHBondContact O-N 2.65Å; R208-S210 VanDerWaalsContact C-N 3.28Å; R208-S210 PolarHBondContact O-N 3.33Å; R208-G212 PolarHBondContact O-N 3.23Å; R208-G212 VanDerWaalsContact O-N 3.07Å; R208-M441 HydrophobicContact CB-SD 4.33Å; R208-M441 PolarHBondContact NE-O 3.32Å; R208-M441 PolarHBondContact NH2-O 3.5Å
209	L	89.8	Confident	85.1	Confident	1 Å²	1	58.2 Å²	58.2	1%	0.005	30%	0.295	C	S	.	.	H	α-helix	trans	-65	-32.1	177.2	177.4	57.4	0	0	0	111.7	V205 C206 L207 P213 L272 A276 T438 V442 V455 W459	V205-L209 VanDerWaalsContact O-CB 3.27Å; V205-L209 WeakPolarHBondContact O-CB 3.4Å; V205-L209 PolarHBondContact O-N 3.5Å; C206-L209 PolarHBondContact O-N 2.9Å; L207-L209 PolarHBondContact O-N 3.2Å; L209-P213 WeakPolarHBondContact O-CD 3.43Å; L209-P213 VanDerWaalsContact O-CG 3.22Å; L209-P213 WeakPolarHBondContact O-CG 3.5Å; L209-L272 HydrophobicContact CD2-CD1 4.3Å; L209-L272 HydrophobicContact CD2-CD2 4.07Å; L209-L272 HydrophobicContact CD2-CG 3.87Å; L209-A276 HydrophobicContact CB-CB 4.25Å; L209-A276 HydrophobicContact CD2-CB 3.71Å; L209-A276 HydrophobicContact CG-CB 3.84Å; L209-T438 HydrophobicContact CD1-CG2 3.61Å; L209-V442 HydrophobicContact CD1-CG2 3.79Å; L209-V455 HydrophobicContact CD1-CG1 4.02Å; L209-V455 HydrophobicContact CD2-CG1 4.17Å; L209-W459 HydrophobicContact CD1-CD2 4.27Å; L209-W459 HydrophobicContact CD1-CE3 4.3Å; L209-W459 HydrophobicContact CD1-CH2 4.35Å; L209-W459 HydrophobicContact CD1-CZ2 4.24Å; L209-W459 HydrophobicContact CD1-CZ3 4.36Å; L209-W459 HydrophobicContact CD2-CZ2 4.34Å; L209-W459 HydrophobicContact CG-CH2 4.04Å; L209-W459 HydrophobicContact CG-CZ2 3.87Å; L209-W459 HydrophobicContact CG-CZ3 4.5Å; L209-W459 WeakPolarHBondContact O-CH2 3.35Å; L209-W459 WeakPolarHBondContact O-CZ3 3.47Å
210	S	88.1	Confident	86.6	Confident	0 Å²	0	55.9 Å²	55.9	0%	0	28%	0.283	C	S	.	.	H	α-helix	trans	-80.9	-47	-180	-46.8	0	0	0	0	112.8	C206 L207 R208 C214 A276 I279	C206-S210 WeakPolarHBondContact O-CB 3.06Å; C206-S210 PolarHBondContact O-N 3.34Å; C206-S210 PolarHBondContact O-OG 2.91Å; L207-S210 PolarHBondContact O-N 3.43Å; R208-S210 VanDerWaalsContact C-N 3.28Å; R208-S210 PolarHBondContact O-N 3.33Å; S210-C214 WeakPolarHBondContact O-CB 3.42Å; S210-A276 WeakPolarHBondContact OG-CA 3.22Å; S210-A276 WeakPolarHBondContact OG-CB 3.01Å; S210-A276 PolarHBondContact OG-O 3.32Å; S210-A276 VanDerWaalsContact OG-O 3.12Å; S210-I279 WeakPolarHBondContact OG-CB 3.14Å
211	F	91.9	Very high	87.8	Confident	80 Å²	80	47.6 Å²	47.6	35%	0.351	25%	0.247	S	C	.	.	H	α-helix	trans	-80.5	-42.7	-173.7	-82.4	-113.2	0	0	0	112.8	L207 I215 I279 L283	L207-F211 HydrophobicContact CD1-CD2 3.55Å; L207-F211 HydrophobicContact CD1-CE2 3.34Å; L207-F211 HydrophobicContact CD1-CZ 4.19Å; L207-F211 HydrophobicContact CG-CD2 3.97Å; L207-F211 HydrophobicContact CG-CE2 4.24Å; L207-F211 WeakPolarHBondContact O-CB 3.39Å; L207-F211 PolarHBondContact O-N 3.41Å; F211-I215 HydrophobicContact CB-CD1 4.29Å; F211-I215 HydrophobicContact CD1-CD1 3.97Å; F211-I215 VanDerWaalsContact O-CB 3.3Å; F211-I215 WeakPolarHBondContact O-CB 3.27Å; F211-I215 VanDerWaalsContact O-CG1 3.27Å; F211-I215 WeakPolarHBondContact O-CG1 3.34Å; F211-I215 PolarHBondContact O-N 2.93Å; F211-I279 HydrophobicContact CD2-CG2 4.46Å; F211-I279 HydrophobicContact CE2-CG2 3.94Å; F211-L283 HydrophobicContact CB-CD2 4.2Å; F211-L283 HydrophobicContact CD1-CD1 4.21Å; F211-L283 HydrophobicContact CD1-CD2 3.69Å; F211-L283 HydrophobicContact CD2-CD2 3.96Å; F211-L283 HydrophobicContact CE1-CD1 3.71Å; F211-L283 HydrophobicContact CE1-CD2 3.94Å; F211-L283 HydrophobicContact CE1-CG 4.43Å; F211-L283 HydrophobicContact CE2-CD2 4.17Å; F211-L283 HydrophobicContact CG-CD2 3.7Å; F211-L283 HydrophobicContact CZ-CD1 4Å; F211-L283 HydrophobicContact CZ-CD2 4.17Å
212	G	93.9	Very high	89.4	Confident	17 Å²	17	39 Å²	39	18%	0.175	21%	0.21	C	C	.	.	H	α-helix	trans	-60.9	-57.5	-173.1	0	0	0	0	0	113.5	R208 S216	R208-G212 PolarHBondContact O-N 3.23Å; R208-G212 VanDerWaalsContact O-N 3.07Å; G212-S216 VanDerWaalsContact O-CB 3.26Å; G212-S216 WeakPolarHBondContact O-CB 3.28Å; G212-S216 PolarHBondContact O-N 3.15Å; G212-S216 PolarHBondContact O-OG 3.39Å; G212-S216 VanDerWaalsContact O-OG 3.07Å
213	P	94.8	Very high	91.1	Very high	0 Å²	0	39 Å²	39	0%	0	21%	0.213	C	C	.	.	H	α-helix	trans	-61.1	-51.6	177.4	-23.8	37.2	0	0	0	112.3	L209 I215 S216 E217 R434 T438 W459	L209-P213 WeakPolarHBondContact O-CD 3.43Å; L209-P213 VanDerWaalsContact O-CG 3.22Å; L209-P213 WeakPolarHBondContact O-CG 3.5Å; P213-I215 PolarHBondContact O-N 3.42Å; P213-S216 WeakPolarHBondContact CA-OG 3.4Å; P213-S216 PolarHBondContact O-N 2.84Å; P213-S216 PolarHBondContact O-OG 3.18Å; P213-E217 WeakPolarHBondContact O-CB 3.48Å; P213-E217 PolarHBondContact O-N 2.87Å; P213-R434 HydrophobicContact CB-CG 3.94Å; P213-T438 WeakPolarHBondContact CB-OG1 3.12Å; P213-T438 HydrophobicContact CG-CG2 4.42Å; P213-T438 VanDerWaalsContact CG-OG1 3.29Å; P213-T438 WeakPolarHBondContact CG-OG1 3.47Å; P213-W459 HydrophobicContact CB-CE3 3.88Å; P213-W459 HydrophobicContact CB-CZ3 3.99Å; P213-W459 HydrophobicContact CG-CE3 4.03Å; P213-W459 HydrophobicContact CG-CZ3 4.02Å
214	C	94.9	Very high	92.3	Very high	0 Å²	0	32.3 Å²	32.3	0%	0	18%	0.184	C	C	.	.	H	α-helix	trans	-52.6	-51.6	179.7	-175.7	0	0	0	0	112.3	S210 T218 D280 L283	S210-C214 WeakPolarHBondContact O-CB 3.42Å; C214-T218 WeakPolarHBondContact O-CB 3.48Å; C214-T218 PolarHBondContact O-N 3.4Å; C214-T218 PolarHBondContact O-OG1 3.47Å; C214-D280 WeakPolarHBondContact CB-OD1 3.42Å; C214-L283 HydrophobicContact CB-CD2 3.91Å
215	I	95.7	Very high	93	Very high	77 Å²	77	29.2 Å²	29.2	40%	0.395	16%	0.159	S	C	.	.	H	α-helix	trans	-68.9	-41.7	-178.4	-65.7	171.3	0	0	0	110.6	F211 P213 E217 T218 C219 L283	F211-I215 HydrophobicContact CB-CD1 4.29Å; F211-I215 HydrophobicContact CD1-CD1 3.97Å; F211-I215 VanDerWaalsContact O-CB 3.3Å; F211-I215 WeakPolarHBondContact O-CB 3.27Å; F211-I215 VanDerWaalsContact O-CG1 3.27Å; F211-I215 WeakPolarHBondContact O-CG1 3.34Å; F211-I215 PolarHBondContact O-N 2.93Å; P213-I215 PolarHBondContact O-N 3.42Å; I215-E217 PolarHBondContact O-N 2.87Å; I215-T218 PolarHBondContact O-N 3.19Å; I215-C219 WeakPolarHBondContact O-CB 3.29Å; I215-C219 PolarHBondContact O-N 3.46Å; I215-C219 PolarHBondContact O-SG 2.83Å; I215-L283 HydrophobicContact CD1-CD2 4.46Å; I215-L283 HydrophobicContact CG1-CD2 4.25Å
216	S	96.1	Very high	93.5	Very high	30 Å²	30	31.9 Å²	31.9	21%	0.21	16%	0.164	C	C	.	.	H	α-helix	trans	-63.4	-40.8	178.9	70.1	0	0	0	0	112.8	G212 P213 T220 A437	G212-S216 VanDerWaalsContact O-CB 3.26Å; G212-S216 WeakPolarHBondContact O-CB 3.28Å; G212-S216 PolarHBondContact O-N 3.15Å; G212-S216 PolarHBondContact O-OG 3.39Å; G212-S216 VanDerWaalsContact O-OG 3.07Å; P213-S216 WeakPolarHBondContact CA-OG 3.4Å; P213-S216 PolarHBondContact O-N 2.84Å; P213-S216 PolarHBondContact O-OG 3.18Å; S216-T220 VanDerWaalsContact O-CB 3.31Å; S216-T220 WeakPolarHBondContact O-CB 3.44Å; S216-T220 PolarHBondContact O-N 3.32Å; S216-T220 PolarHBondContact O-OG1 3.18Å; S216-A437 WeakPolarHBondContact OG-CB 3.5Å
217	E	96.1	Very high	94	Very high	0 Å²	0	36.4 Å²	36.4	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-69.7	-44.3	175.9	-172.1	171.4	-146.7	0	0	110.6	P213 I215 C219 T220 A221 A430 R434 K462	P213-E217 WeakPolarHBondContact O-CB 3.48Å; P213-E217 PolarHBondContact O-N 2.87Å; I215-E217 PolarHBondContact O-N 2.87Å; E217-C219 PolarHBondContact O-N 2.77Å; E217-T220 PolarHBondContact O-N 3.2Å; E217-A221 VanDerWaalsContact O-CB 3.26Å; E217-A221 WeakPolarHBondContact O-CB 3.49Å; E217-A221 PolarHBondContact O-N 3.24Å; E217-A430 HydrophobicContact CG-CB 3.86Å; E217-R434 HydrophobicContact CB-CB 4.09Å; E217-R434 HydrophobicContact CB-CG 4.28Å; E217-R434 HydrophobicContact CG-CB 4.26Å; E217-R434 WeakPolarHBondContact OE2-CD 3.32Å; E217-R434 IonicContact OE2-CZ 3.96Å; E217-R434 IonicContact OE2-NE 3.14Å; E217-R434 IonicContact OE2-NH1 3.26Å; E217-R434 PolarHBondContact OE2-NH1 3.11Å; E217-K462 IonicContact OE1-NZ 3.49Å; E217-K462 PolarHBondContact OE1-NZ 2.95Å; E217-K462 IonicContact OE2-NZ 3.66Å; E217-K462 PolarHBondContact OE2-NZ 3.22Å
218	T	96.6	Very high	94.2	Very high	2 Å²	2	35.6 Å²	35.6	1%	0.012	18%	0.181	C	C	.	.	H	α-helix	trans	-56.5	-51.2	176.6	-64.6	0	0	0	0	111.5	C214 I215 A221 A222 F237 G240 F241	C214-T218 WeakPolarHBondContact O-CB 3.48Å; C214-T218 PolarHBondContact O-N 3.4Å; C214-T218 PolarHBondContact O-OG1 3.47Å; I215-T218 PolarHBondContact O-N 3.19Å; T218-A221 PolarHBondContact O-N 3.08Å; T218-A222 VanDerWaalsContact O-CB 3.27Å; T218-A222 WeakPolarHBondContact O-CB 3.43Å; T218-A222 PolarHBondContact O-N 3.1Å; T218-F237 HydrophobicContact CG2-CD1 4.04Å; T218-G240 PolarHBondContact OG1-O 2.86Å; T218-F241 HydrophobicContact CG2-CD1 3.79Å; T218-F241 HydrophobicContact CG2-CD2 3.95Å; T218-F241 HydrophobicContact CG2-CE1 3.83Å; T218-F241 HydrophobicContact CG2-CE2 3.97Å; T218-F241 HydrophobicContact CG2-CG 3.86Å; T218-F241 HydrophobicContact CG2-CZ 3.92Å
219	C	96.8	Very high	94.1	Very high	54 Å²	54	32 Å²	32	37%	0.365	17%	0.169	S	C	.	.	H	α-helix	trans	-65	-40	179	-69.2	0	0	0	0	112	I215 E217 A222 V223	I215-C219 WeakPolarHBondContact O-CB 3.29Å; I215-C219 PolarHBondContact O-N 3.46Å; I215-C219 PolarHBondContact O-SG 2.83Å; E217-C219 PolarHBondContact O-N 2.77Å; C219-A222 PolarHBondContact O-N 2.87Å; C219-V223 WeakPolarHBondContact O-CG2 3.5Å; C219-V223 PolarHBondContact O-N 3.5Å
220	T	96.9	Very high	94.1	Very high	30 Å²	30	39.1 Å²	39.1	18%	0.184	20%	0.202	C	C	.	.	H	α-helix	trans	-63.1	-50.7	176.7	-59.3	0	0	0	0	110.7	S216 E217 A222 V223 L224 I429 A430 V433	S216-T220 VanDerWaalsContact O-CB 3.31Å; S216-T220 WeakPolarHBondContact O-CB 3.44Å; S216-T220 PolarHBondContact O-N 3.32Å; S216-T220 PolarHBondContact O-OG1 3.18Å; E217-T220 PolarHBondContact O-N 3.2Å; T220-A222 VanDerWaalsContact C-N 3.33Å; T220-A222 PolarHBondContact O-N 2.95Å; T220-V223 PolarHBondContact O-N 3.1Å; T220-L224 HydrophobicContact CG2-CD1 3.81Å; T220-L224 HydrophobicContact CG2-CG 4.46Å; T220-L224 WeakPolarHBondContact O-CB 3.24Å; T220-L224 VanDerWaalsContact O-CG 3.24Å; T220-L224 WeakPolarHBondContact O-CG 3.3Å; T220-L224 PolarHBondContact O-N 3.28Å; T220-I429 HydrophobicContact CG2-CG2 4.21Å; T220-A430 HydrophobicContact CG2-CB 4.39Å; T220-V433 HydrophobicContact CG2-CB 4.31Å; T220-V433 HydrophobicContact CG2-CG2 3.91Å; T220-V433 WeakPolarHBondContact OG1-CG1 3.2Å
221	A	96.3	Very high	94.2	Very high	0 Å²	0	39.2 Å²	39.2	0%	0	20%	0.202	C	C	.	.	H	α-helix	trans	-61.3	-38.9	177.2	0	0	0	0	0	112.2	E217 T218 L224 A225 L243 A430	E217-A221 VanDerWaalsContact O-CB 3.26Å; E217-A221 WeakPolarHBondContact O-CB 3.49Å; E217-A221 PolarHBondContact O-N 3.24Å; T218-A221 PolarHBondContact O-N 3.08Å; A221-L224 PolarHBondContact O-N 3.08Å; A221-A225 WeakPolarHBondContact O-CB 3.46Å; A221-A225 PolarHBondContact O-N 3.47Å; A221-L243 HydrophobicContact CB-CB 4.5Å; A221-L243 HydrophobicContact CB-CD1 4.02Å; A221-A430 HydrophobicContact CB-CB 4.13Å
222	A	96.4	Very high	94.2	Very high	0 Å²	0	37.3 Å²	37.3	0%	0	20%	0.197	C	C	.	.	H	α-helix	trans	-65.1	-43.2	176.7	0	0	0	0	0	112.9	T218 C219 T220 A225 Y226 G236 F237	T218-A222 VanDerWaalsContact O-CB 3.27Å; T218-A222 WeakPolarHBondContact O-CB 3.43Å; T218-A222 PolarHBondContact O-N 3.1Å; C219-A222 PolarHBondContact O-N 2.87Å; T220-A222 VanDerWaalsContact C-N 3.33Å; T220-A222 PolarHBondContact O-N 2.95Å; A222-A225 PolarHBondContact O-N 3.37Å; A222-Y226 PolarHBondContact O-N 3.2Å; A222-G236 VanDerWaalsContact CA-O 3.31Å; A222-G236 WeakPolarHBondContact CA-O 3.24Å; A222-G236 WeakPolarHBondContact CB-O 3.5Å; A222-F237 HydrophobicContact CB-CD1 3.77Å; A222-F237 HydrophobicContact CB-CD2 4.39Å; A222-F237 HydrophobicContact CB-CE1 3.92Å; A222-F237 HydrophobicContact CB-CG 4.01Å; A222-F237 HydrophobicContact CB-CZ 4.28Å
223	V	96.9	Very high	94.1	Very high	64 Å²	64	42 Å²	42	39%	0.388	21%	0.21	S	C	.	.	H	α-helix	trans	-64.3	-44.4	174.9	170.3	0	0	0	0	110.9	C219 T220 Y226 L227 W233	C219-V223 WeakPolarHBondContact O-CG2 3.5Å; C219-V223 PolarHBondContact O-N 3.5Å; T220-V223 PolarHBondContact O-N 3.1Å; V223-Y226 PolarHBondContact O-N 3.08Å; V223-L227 HydrophobicContact CG1-CD1 3.78Å; V223-L227 HydrophobicContact CG1-CG 4.41Å; V223-L227 WeakPolarHBondContact O-CB 3.47Å; V223-L227 VanDerWaalsContact O-CG 3.29Å; V223-L227 WeakPolarHBondContact O-CG 3.34Å; V223-L227 PolarHBondContact O-N 3.22Å; V223-W233 HydrophobicContact CG2-CH2 4.19Å; V223-W233 HydrophobicContact CG2-CZ3 4.05Å
224	L	95.5	Very high	93.9	Very high	19 Å²	19	45.8 Å²	45.8	10%	0.099	23%	0.228	C	C	.	.	H	α-helix	trans	-67.4	-36.4	178	-66.1	171.7	0	0	0	112.3	T220 A221 L227 F228 T426 I429	T220-L224 HydrophobicContact CG2-CD1 3.81Å; T220-L224 HydrophobicContact CG2-CG 4.46Å; T220-L224 WeakPolarHBondContact O-CB 3.24Å; T220-L224 VanDerWaalsContact O-CG 3.24Å; T220-L224 WeakPolarHBondContact O-CG 3.3Å; T220-L224 PolarHBondContact O-N 3.28Å; A221-L224 PolarHBondContact O-N 3.08Å; L224-L227 PolarHBondContact O-N 3.3Å; L224-F228 HydrophobicContact CB-CD2 4.46Å; L224-F228 HydrophobicContact CD2-CD2 4.34Å; L224-F228 HydrophobicContact CD2-CE2 3.77Å; L224-F228 HydrophobicContact CD2-CZ 3.87Å; L224-F228 VanDerWaalsContact O-CB 3.28Å; L224-F228 WeakPolarHBondContact O-CB 3.19Å; L224-F228 PolarHBondContact O-N 3.02Å; L224-T426 HydrophobicContact CB-CG2 3.89Å; L224-T426 HydrophobicContact CD1-CG2 4.49Å; L224-I429 HydrophobicContact CD1-CB 3.68Å; L224-I429 HydrophobicContact CD1-CD1 4.26Å; L224-I429 HydrophobicContact CD1-CG2 3.69Å; L224-I429 HydrophobicContact CD2-CD1 4.28Å
225	A	94.3	Very high	93.8	Very high	0 Å²	0	46 Å²	46	0%	0	23%	0.229	C	C	.	.	H	α-helix	trans	-62	-42.8	173.6	0	0	0	0	0	112.1	A221 A222 M229 H230 L231 L239	A221-A225 WeakPolarHBondContact O-CB 3.46Å; A221-A225 PolarHBondContact O-N 3.47Å; A222-A225 PolarHBondContact O-N 3.37Å; A225-M229 CarbonylContact O-C 3.44Å; A225-M229 WeakPolarHBondContact O-CA 3.28Å; A225-M229 WeakPolarHBondContact O-CB 3.46Å; A225-M229 PolarHBondContact O-N 2.94Å; A225-H230 PolarHBondContact O-N 3.49Å; A225-L231 HydrophobicContact CB-CB 4.5Å; A225-L231 HydrophobicContact CB-CD1 4.23Å; A225-L231 PolarHBondContact O-N 3.14Å; A225-L239 HydrophobicContact CB-CD2 3.96Å
226	Y	94.3	Very high	93.8	Very high	103 Å²	103	42.4 Å²	42.4	40%	0.404	21%	0.21	S	C	.	.	H	α-helix	trans	-64.7	-43.8	174.6	-179.5	-95.5	0	0	0	112.1	A222 V223 H230 L231 W233	A222-Y226 PolarHBondContact O-N 3.2Å; V223-Y226 PolarHBondContact O-N 3.08Å; Y226-H230 WeakPolarHBondContact O-CA 3.42Å; Y226-H230 PolarHBondContact O-N 3.29Å; Y226-L231 WeakPolarHBondContact CD2-O 3.43Å; Y226-W233 HydrophobicContact CD1-CH2 4.32Å; Y226-W233 AromaticContact CD1-CZ2 3.87Å; Y226-W233 HydrophobicContact CD1-CZ2 3.87Å; Y226-W233 HydrophobicContact CD2-CD2 4.16Å; Y226-W233 AromaticContact CD2-CE2 3.82Å; Y226-W233 HydrophobicContact CD2-CG 4.35Å; Y226-W233 HydrophobicContact CD2-CZ2 4.23Å; Y226-W233 AromaticContact CD2-NE1 3.78Å; Y226-W233 HydrophobicContact CE1-CZ2 4.12Å; Y226-W233 AromaticContact CE2-CD1 4Å; Y226-W233 AromaticContact CE2-CE2 4Å; Y226-W233 HydrophobicContact CE2-CZ2 4.46Å; Y226-W233 AromaticContact CE2-NE1 3.54Å; Y226-W233 HydrophobicContact CG-CD2 4.41Å; Y226-W233 AromaticContact CG-CE2 3.99Å; Y226-W233 HydrophobicContact CG-CH2 4.31Å; Y226-W233 AromaticContact CG-CZ2 3.94Å; Y226-W233 HydrophobicContact CG-CZ2 3.94Å; Y226-W233 AromaticContact CZ-NE1 3.93Å
227	L	92.9	Very high	93.8	Very high	98 Å²	98	44.1 Å²	44.1	51%	0.513	21%	0.214	S	C	.	.	H	α-helix	trans	-77.7	-42.4	-175.9	-68.1	175.1	0	0	0	114.3	V223 L224	V223-L227 HydrophobicContact CG1-CD1 3.78Å; V223-L227 HydrophobicContact CG1-CG 4.41Å; V223-L227 WeakPolarHBondContact O-CB 3.47Å; V223-L227 VanDerWaalsContact O-CG 3.29Å; V223-L227 WeakPolarHBondContact O-CG 3.34Å; V223-L227 PolarHBondContact O-N 3.22Å; L224-L227 PolarHBondContact O-N 3.3Å
228	F	90.4	Very high	93.7	Very high	74 Å²	74	44.1 Å²	44.1	33%	0.325	21%	0.214	S	C	.	.	H	α-helix	trans	-97.1	-34	-173.4	-65.2	-10.9	0	0	0	113.3	L224 L422 A425 I429	L224-F228 HydrophobicContact CB-CD2 4.46Å; L224-F228 HydrophobicContact CD2-CD2 4.34Å; L224-F228 HydrophobicContact CD2-CE2 3.77Å; L224-F228 HydrophobicContact CD2-CZ 3.87Å; L224-F228 VanDerWaalsContact O-CB 3.28Å; L224-F228 WeakPolarHBondContact O-CB 3.19Å; L224-F228 PolarHBondContact O-N 3.02Å; F228-L422 HydrophobicContact CB-CB 4.46Å; F228-L422 HydrophobicContact CB-CD2 4.17Å; F228-L422 HydrophobicContact CD2-CD2 4.49Å; F228-L422 HydrophobicContact CG-CD2 4.29Å; F228-A425 HydrophobicContact CE2-CB 4.38Å; F228-I429 HydrophobicContact CE2-CD1 4.18Å; F228-I429 HydrophobicContact CZ-CD1 4.5Å
229	M	87.4	Confident	93.6	Very high	23 Å²	23	44 Å²	44	11%	0.113	21%	0.213	C	C	.	.	S	Bend	trans	-106.5	-3.3	-175.2	-53.5	179	70.2	0	0	112.5	A225 L231 L239 D491 V495	A225-M229 CarbonylContact O-C 3.44Å; A225-M229 WeakPolarHBondContact O-CA 3.28Å; A225-M229 WeakPolarHBondContact O-CB 3.46Å; A225-M229 PolarHBondContact O-N 2.94Å; M229-L231 HydrophobicContact CB-CD1 4.23Å; M229-L231 HydrophobicContact CB-CG 3.96Å; M229-L231 PolarHBondContact O-N 3.12Å; M229-L231 VanDerWaalsContact O-N 3.16Å; M229-L239 HydrophobicContact SD-CD2 4.02Å; M229-D491 HydrophobicContact CE-CB 3.79Å; M229-V495 HydrophobicContact CE-CG2 3.7Å; M229-V495 HydrophobicContact SD-CG2 3.97Å
230	H	90	Very high	93.6	Very high	151 Å²	151	41.5 Å²	41.5	70%	0.699	20%	0.196	S	C	*	.			trans	53.7	29.2	-176.5	-56.2	-54.9	0	0	0	113.8	A225 Y226	A225-H230 PolarHBondContact O-N 3.49Å; Y226-H230 WeakPolarHBondContact O-CA 3.42Å; Y226-H230 PolarHBondContact O-N 3.29Å
231	L	90.5	Very high	93.5	Very high	1 Å²	1	41.5 Å²	41.5	1%	0.005	19%	0.194	C	C	.	.			trans	-74.6	138.1	176.5	-68.2	179.5	0	0	0	110.5	A225 Y226 M229 W235 L239 Y488 D491	A225-L231 HydrophobicContact CB-CB 4.5Å; A225-L231 HydrophobicContact CB-CD1 4.23Å; A225-L231 PolarHBondContact O-N 3.14Å; Y226-L231 WeakPolarHBondContact CD2-O 3.43Å; M229-L231 HydrophobicContact CB-CD1 4.23Å; M229-L231 HydrophobicContact CB-CG 3.96Å; M229-L231 PolarHBondContact O-N 3.12Å; M229-L231 VanDerWaalsContact O-N 3.16Å; L231-W235 HydrophobicContact CB-CB 4.19Å; L231-L239 HydrophobicContact CD1-CD2 4.26Å; L231-Y488 HydrophobicContact CD2-CD1 3.28Å; L231-Y488 HydrophobicContact CD2-CE1 3.99Å; L231-Y488 HydrophobicContact CD2-CG 3.79Å; L231-D491 HydrophobicContact CD2-CB 4.47Å
232	P	92.4	Very high	93.4	Very high	40 Å²	40	41.5 Å²	41.5	26%	0.26	19%	0.194	S	C	.	.			trans	-56.1	151.2	170.8	-23.8	33.1	0	0	0	111.7	Q234 W235 G236 Y488	P232-Q234 PolarHBondContact O-N 3.36Å; P232-W235 CarbonylContact O-C 3.58Å; P232-W235 WeakPolarHBondContact O-CA 3.4Å; P232-W235 PolarHBondContact O-N 2.81Å; P232-G236 PolarHBondContact O-N 2.92Å; P232-Y488 HydrophobicContact CG-CD2 4.42Å; P232-Y488 HydrophobicContact CG-CE2 3.71Å
233	W	91.8	Very high	93.3	Very high	116 Å²	116	41.5 Å²	41.5	44%	0.439	19%	0.194	S	C	.	.	H	α-helix	trans	-50.5	-38.9	-176.5	-75	105.7	0	0	0	114.1	V223 Y226 G236 F237	V223-W233 HydrophobicContact CG2-CH2 4.19Å; V223-W233 HydrophobicContact CG2-CZ3 4.05Å; Y226-W233 HydrophobicContact CD1-CH2 4.32Å; Y226-W233 AromaticContact CD1-CZ2 3.87Å; Y226-W233 HydrophobicContact CD1-CZ2 3.87Å; Y226-W233 HydrophobicContact CD2-CD2 4.16Å; Y226-W233 AromaticContact CD2-CE2 3.82Å; Y226-W233 HydrophobicContact CD2-CG 4.35Å; Y226-W233 HydrophobicContact CD2-CZ2 4.23Å; Y226-W233 AromaticContact CD2-NE1 3.78Å; Y226-W233 HydrophobicContact CE1-CZ2 4.12Å; Y226-W233 AromaticContact CE2-CD1 4Å; Y226-W233 AromaticContact CE2-CE2 4Å; Y226-W233 HydrophobicContact CE2-CZ2 4.46Å; Y226-W233 AromaticContact CE2-NE1 3.54Å; Y226-W233 HydrophobicContact CG-CD2 4.41Å; Y226-W233 AromaticContact CG-CE2 3.99Å; Y226-W233 HydrophobicContact CG-CH2 4.31Å; Y226-W233 AromaticContact CG-CZ2 3.94Å; Y226-W233 HydrophobicContact CG-CZ2 3.94Å; Y226-W233 AromaticContact CZ-NE1 3.93Å; W233-G236 PolarHBondContact O-N 3.19Å; W233-F237 HydrophobicContact CE3-CE2 4.12Å; W233-F237 WeakPolarHBondContact O-CD2 3.32Å; W233-F237 PolarHBondContact O-N 2.85Å
234	Q	90.6	Very high	93.2	Very high	80 Å²	80	38.4 Å²	38.4	37%	0.374	18%	0.175	S	C	.	.	H	α-helix	trans	-60.1	-48.1	176.8	-58.4	80	-2.2	0	0	111.1	P232 F237 I238 A295	P232-Q234 PolarHBondContact O-N 3.36Å; Q234-F237 PolarHBondContact O-N 2.98Å; Q234-I238 VanDerWaalsContact O-CG1 3.31Å; Q234-I238 WeakPolarHBondContact O-CG1 3.36Å; Q234-I238 PolarHBondContact O-N 2.93Å; Q234-A295 HydrophobicContact CB-CB 4.08Å
235	W	92.6	Very high	93	Very high	5 Å²	5	37.5 Å²	37.5	2%	0.019	17%	0.17	C	C	.	.	H	α-helix	trans	-69.5	-33.9	176.7	-74.5	95.3	0	0	0	112.7	L231 P232 I238 L239 F296 A473 A477 L485 Y488 V492	L231-W235 HydrophobicContact CB-CB 4.19Å; P232-W235 CarbonylContact O-C 3.58Å; P232-W235 WeakPolarHBondContact O-CA 3.4Å; P232-W235 PolarHBondContact O-N 2.81Å; W235-I238 HydrophobicContact CD2-CD1 4.24Å; W235-I238 HydrophobicContact CE3-CD1 4.18Å; W235-I238 PolarHBondContact O-N 2.81Å; W235-L239 WeakPolarHBondContact O-CB 3.29Å; W235-L239 PolarHBondContact O-N 3.44Å; W235-F296 HydrophobicContact CH2-CE2 4.13Å; W235-F296 AromaticContact CH2-CZ 3.98Å; W235-F296 HydrophobicContact CH2-CZ 3.98Å; W235-F296 AromaticContact CZ2-CE2 3.96Å; W235-F296 HydrophobicContact CZ2-CE2 3.96Å; W235-F296 AromaticContact CZ2-CZ 3.74Å; W235-F296 HydrophobicContact CZ2-CZ 3.74Å; W235-A473 HydrophobicContact CH2-CB 4.18Å; W235-A473 HydrophobicContact CZ3-CB 3.74Å; W235-A477 HydrophobicContact CH2-CB 4.39Å; W235-L485 HydrophobicContact CZ2-CB 4.07Å; W235-L485 HydrophobicContact CZ2-CD2 3.95Å; W235-Y488 AromaticContact CD1-CD2 3.69Å; W235-Y488 HydrophobicContact CD2-CD2 4.18Å; W235-Y488 HydrophobicContact CD2-CG 4.3Å; W235-Y488 AromaticContact CE2-CD2 3.98Å; W235-Y488 HydrophobicContact CG-CD2 4.03Å; W235-Y488 HydrophobicContact CG-CG 4.28Å; W235-Y488 AromaticContact NE1-CD2 3.66Å; W235-V492 HydrophobicContact CE3-CG2 3.94Å; W235-V492 HydrophobicContact CZ3-CG2 4.31Å
236	G	95.2	Very high	92.8	Very high	0 Å²	0	37.6 Å²	37.6	0%	0	17%	0.171	C	C	.	.	H	α-helix	trans	-60.1	-44.6	169.7	0	0	0	0	0	112.3	A222 P232 W233 L239 G240	A222-G236 VanDerWaalsContact CA-O 3.31Å; A222-G236 WeakPolarHBondContact CA-O 3.24Å; A222-G236 WeakPolarHBondContact CB-O 3.5Å; P232-G236 PolarHBondContact O-N 2.92Å; W233-G236 PolarHBondContact O-N 3.19Å; G236-L239 PolarHBondContact O-N 3.09Å; G236-G240 PolarHBondContact O-N 3.49Å
237	F	95.1	Very high	92.4	Very high	67 Å²	67	32.7 Å²	32.7	29%	0.294	15%	0.152	S	C	.	.	H	α-helix	trans	-71.9	-34.1	174.9	-79.6	-69.4	0	0	0	113.3	T218 A222 W233 Q234 G240 F241 C291	T218-F237 HydrophobicContact CG2-CD1 4.04Å; A222-F237 HydrophobicContact CB-CD1 3.77Å; A222-F237 HydrophobicContact CB-CD2 4.39Å; A222-F237 HydrophobicContact CB-CE1 3.92Å; A222-F237 HydrophobicContact CB-CG 4.01Å; A222-F237 HydrophobicContact CB-CZ 4.28Å; W233-F237 HydrophobicContact CE3-CE2 4.12Å; W233-F237 WeakPolarHBondContact O-CD2 3.32Å; W233-F237 PolarHBondContact O-N 2.85Å; Q234-F237 PolarHBondContact O-N 2.98Å; F237-G240 PolarHBondContact O-N 3.24Å; F237-F241 VanDerWaalsContact O-CD2 3.24Å; F237-F241 WeakPolarHBondContact O-CD2 3.38Å; F237-F241 PolarHBondContact O-N 3.35Å; F237-C291 HydrophobicContact CB-CB 4.43Å
238	I	94.5	Very high	91.8	Very high	0 Å²	0	29.6 Å²	29.6	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-56.2	-53.1	169.1	-72.9	170.7	0	0	0	109.6	Q234 W235 G240 F241 V242 F288 C291 L292 A295 A473 V492	Q234-I238 VanDerWaalsContact O-CG1 3.31Å; Q234-I238 WeakPolarHBondContact O-CG1 3.36Å; Q234-I238 PolarHBondContact O-N 2.93Å; W235-I238 HydrophobicContact CD2-CD1 4.24Å; W235-I238 HydrophobicContact CE3-CD1 4.18Å; W235-I238 PolarHBondContact O-N 2.81Å; I238-G240 VanDerWaalsContact C-N 3.3Å; I238-G240 PolarHBondContact O-N 2.98Å; I238-F241 PolarHBondContact O-N 2.91Å; I238-V242 WeakPolarHBondContact O-CG2 3.24Å; I238-V242 PolarHBondContact O-N 3.13Å; I238-F288 HydrophobicContact CG2-CD2 3.91Å; I238-F288 HydrophobicContact CG2-CE2 3.56Å; I238-C291 HydrophobicContact CG1-CB 3.67Å; I238-L292 HydrophobicContact CD1-CD1 4.29Å; I238-A295 HydrophobicContact CD1-CB 3.74Å; I238-A473 HydrophobicContact CG2-CB 3.97Å; I238-V492 HydrophobicContact CG2-CG1 4.31Å; I238-V492 HydrophobicContact CG2-CG2 4.32Å
239	L	95.3	Very high	91.3	Very high	0 Å²	0	28 Å²	28	0%	0	14%	0.137	C	C	.	.	H	α-helix	trans	-60.1	-41.9	175.7	179.2	51.6	0	0	0	111.7	A225 M229 L231 W235 G236 F241 V242 L243 V492 V495	A225-L239 HydrophobicContact CB-CD2 3.96Å; M229-L239 HydrophobicContact SD-CD2 4.02Å; L231-L239 HydrophobicContact CD1-CD2 4.26Å; W235-L239 WeakPolarHBondContact O-CB 3.29Å; W235-L239 PolarHBondContact O-N 3.44Å; G236-L239 PolarHBondContact O-N 3.09Å; L239-F241 PolarHBondContact O-N 3.41Å; L239-V242 PolarHBondContact O-N 3.12Å; L239-L243 HydrophobicContact CD1-CD1 4.12Å; L239-L243 HydrophobicContact CD1-CG 4.06Å; L239-L243 HydrophobicContact CG-CD1 4.35Å; L239-L243 PolarHBondContact O-N 2.89Å; L239-V492 HydrophobicContact CB-CG2 4.19Å; L239-V495 HydrophobicContact CD1-CB 3.71Å; L239-V495 HydrophobicContact CD1-CG1 3.75Å; L239-V495 HydrophobicContact CD1-CG2 4.28Å; L239-V495 HydrophobicContact CD2-CB 4.39Å; L239-V495 HydrophobicContact CD2-CG1 4.42Å; L239-V495 HydrophobicContact CD2-CG2 4.08Å
240	G	96	Very high	91.1	Very high	0 Å²	0	27.1 Å²	27.1	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-56.8	-47.4	177.4	0	0	0	0	0	112.4	T218 G236 F237 I238 L243 G244	T218-G240 PolarHBondContact OG1-O 2.86Å; G236-G240 PolarHBondContact O-N 3.49Å; F237-G240 PolarHBondContact O-N 3.24Å; I238-G240 VanDerWaalsContact C-N 3.3Å; I238-G240 PolarHBondContact O-N 2.98Å; G240-L243 CarbonylContact O-C 3.27Å; G240-L243 PolarHBondContact O-N 2.73Å; G240-G244 PolarHBondContact O-N 2.95Å
241	F	95.4	Very high	91	Very high	30 Å²	30	20.1 Å²	20.1	13%	0.132	10%	0.102	C	C	.	.	H	α-helix	trans	-73.2	-32.2	178	-77.6	-62.8	0	0	0	113.2	T218 F237 I238 L239 L243 G244 F288	T218-F241 HydrophobicContact CG2-CD1 3.79Å; T218-F241 HydrophobicContact CG2-CD2 3.95Å; T218-F241 HydrophobicContact CG2-CE1 3.83Å; T218-F241 HydrophobicContact CG2-CE2 3.97Å; T218-F241 HydrophobicContact CG2-CG 3.86Å; T218-F241 HydrophobicContact CG2-CZ 3.92Å; F237-F241 VanDerWaalsContact O-CD2 3.24Å; F237-F241 WeakPolarHBondContact O-CD2 3.38Å; F237-F241 PolarHBondContact O-N 3.35Å; I238-F241 PolarHBondContact O-N 2.91Å; L239-F241 PolarHBondContact O-N 3.41Å; F241-L243 VanDerWaalsContact C-N 3.28Å; F241-L243 PolarHBondContact O-N 2.97Å; F241-G244 PolarHBondContact O-N 3.42Å; F241-F288 HydrophobicContact CB-CB 3.89Å
242	V	94.8	Very high	90.7	Very high	0 Å²	0	22.2 Å²	22.2	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-58.6	-42.6	168.2	170.9	0	0	0	0	110.4	I238 L239 F288 Q466 I469 V492 A496	I238-V242 WeakPolarHBondContact O-CG2 3.24Å; I238-V242 PolarHBondContact O-N 3.13Å; L239-V242 PolarHBondContact O-N 3.12Å; V242-F288 HydrophobicContact CG2-CD2 3.59Å; V242-F288 HydrophobicContact CG2-CE2 3.64Å; V242-Q466 HydrophobicContact CG1-CB 4.38Å; V242-Q466 HydrophobicContact CG1-CG 4.17Å; V242-Q466 WeakPolarHBondContact O-CG 3.47Å; V242-Q466 PolarHBondContact O-NE2 3.44Å; V242-I469 HydrophobicContact CG2-CD1 4Å; V242-I469 HydrophobicContact CG2-CG1 4.26Å; V242-V492 HydrophobicContact CG2-CG1 4.14Å; V242-A496 HydrophobicContact CG1-CB 3.83Å
243	L	94.5	Very high	90.1	Very high	0 Å²	0	23.4 Å²	23.4	0%	0	12%	0.122	C	C	.	.	H	α-helix	trans	-80	-20.2	175.6	-66.2	-176.9	0	0	0	113.8	A221 L239 G240 F241 A245 L427 K462 V495 A499	A221-L243 HydrophobicContact CB-CB 4.5Å; A221-L243 HydrophobicContact CB-CD1 4.02Å; L239-L243 HydrophobicContact CD1-CD1 4.12Å; L239-L243 HydrophobicContact CD1-CG 4.06Å; L239-L243 HydrophobicContact CG-CD1 4.35Å; L239-L243 PolarHBondContact O-N 2.89Å; G240-L243 CarbonylContact O-C 3.27Å; G240-L243 PolarHBondContact O-N 2.73Å; F241-L243 VanDerWaalsContact C-N 3.28Å; F241-L243 PolarHBondContact O-N 2.97Å; L243-A245 VanDerWaalsContact C-N 3.26Å; L243-A245 PolarHBondContact O-N 3.08Å; L243-L427 HydrophobicContact CD2-CD1 4.01Å; L243-K462 HydrophobicContact CD2-CD 4.22Å; L243-K462 WeakPolarHBondContact O-CE 3.48Å; L243-K462 PolarHBondContact O-NZ 2.85Å; L243-V495 HydrophobicContact CD1-CG1 3.92Å; L243-V495 HydrophobicContact CD2-CG1 4.22Å; L243-V495 HydrophobicContact CG-CG1 4.44Å; L243-A499 HydrophobicContact CD2-CB 3.72Å
244	G	93.1	Very high	89.8	Confident	0 Å²	0	18.5 Å²	18.5	0%	0	11%	0.106	C	C	.	.	H	α-helix	trans	-67.6	-24.8	-178.5	0	0	0	0	0	114	G240 F241 R434	G240-G244 PolarHBondContact O-N 2.95Å; F241-G244 PolarHBondContact O-N 3.42Å; G244-R434 PolarHBondContact O-NH1 3.41Å; G244-R434 PolarHBondContact O-NH2 3.39Å
245	A	91.6	Very high	89.6	Confident	0 Å²	0	14.7 Å²	14.7	0%	0	9%	0.088	C	C	.	.			trans	-78.8	137.4	-175.8	0	0	0	0	0	114.4	L243 D280 A284 V465 Q466	L243-A245 VanDerWaalsContact C-N 3.26Å; L243-A245 PolarHBondContact O-N 3.08Å; A245-D280 VanDerWaalsContact CA-OD2 3.31Å; A245-D280 WeakPolarHBondContact CA-OD2 3.44Å; A245-A284 HydrophobicContact CB-CB 3.65Å; A245-V465 HydrophobicContact CB-CB 3.59Å; A245-V465 HydrophobicContact CB-CG1 3.46Å; A245-V465 VanDerWaalsContact CB-CG1 3.46Å; A245-V465 HydrophobicContact CB-CG2 3.99Å; A245-Q466 PolarHBondContact O-NE2 3.26Å
246	V	90.2	Very high	89.3	Confident	2 Å²	2	18.8 Å²	18.8	1%	0.012	11%	0.109	C	C	.	.			trans	-71.9	169.7	160.2	-172.2	0	0	0	0	109.9	V251 D280 D281 W459	V246-V251 HydrophobicContact CG1-CB 4.48Å; V246-V251 HydrophobicContact CG1-CG2 3.54Å; V246-D280 WeakPolarHBondContact CG2-OD2 3.49Å; V246-D280 PolarHBondContact N-OD2 3.47Å; V246-D281 VanDerWaalsContact O-OD1 3.12Å; V246-W459 HydrophobicContact CG2-CD2 3.9Å; V246-W459 HydrophobicContact CG2-CE3 4Å; V246-W459 HydrophobicContact CG2-CG 4.24Å; V246-W459 HydrophobicContact CG2-CH2 4.46Å; V246-W459 HydrophobicContact CG2-CZ2 4.45Å; V246-W459 HydrophobicContact CG2-CZ3 4.26Å
247	S	87.1	Confident	88.7	Confident	0 Å²	0	23.9 Å²	23.9	0%	0	14%	0.135	C	C	.	.			trans	-114.8	104.8	169.6	177.5	0	0	0	0	112.5	A249 V250 V251 P461 A463 T464	S247-A249 PolarHBondContact O-N 2.85Å; S247-A249 VanDerWaalsContact O-N 3.14Å; S247-V250 PolarHBondContact O-N 3.42Å; S247-V251 PolarHBondContact O-N 2.95Å; S247-V251 VanDerWaalsContact O-N 3.09Å; S247-P461 PolarHBondContact N-O 2.74Å; S247-A463 VanDerWaalsContact CB-N 3.27Å; S247-A463 WeakPolarHBondContact OG-CB 3.35Å; S247-T464 PolarHBondContact OG-N 3.42Å; S247-T464 VanDerWaalsContact OG-N 3.11Å; S247-T464 PolarHBondContact OG-OG1 2.96Å
248	P	79.2	Confident	88.4	Confident	32 Å²	32	21.2 Å²	21.2	21%	0.208	12%	0.124	C	C	.	.	H	α-helix	trans	-55.2	-32.5	174.7	-26.1	33.6	0	0	0	113.3	V250 V251 V252 P253 D281	P248-V250 PolarHBondContact O-N 3.32Å; P248-V250 VanDerWaalsContact O-N 3.12Å; P248-V251 PolarHBondContact O-N 3.2Å; P248-V252 HydrophobicContact CB-CG2 3.85Å; P248-V252 VanDerWaalsContact O-CB 3.24Å; P248-V252 WeakPolarHBondContact O-CB 3.26Å; P248-V252 WeakPolarHBondContact O-CG2 3.01Å; P248-V252 PolarHBondContact O-N 3.32Å; P248-P253 WeakPolarHBondContact O-CD 3.39Å; P248-D281 WeakPolarHBondContact CD-OD2 3.27Å; P248-D281 WeakPolarHBondContact CG-OD2 3.44Å
249	A	79.6	Confident	87.8	Confident	40 Å²	40	24.7 Å²	24.7	33%	0.331	14%	0.141	S	C	.	.	H	α-helix	trans	-65.8	-14.1	-179.8	0	0	0	0	0	114.7	L148 S247 T464	L148-A249 HydrophobicContact CD1-CB 3.89Å; S247-A249 PolarHBondContact O-N 2.85Å; S247-A249 VanDerWaalsContact O-N 3.14Å; A249-T464 HydrophobicContact CB-CG2 3.49Å; A249-T464 VanDerWaalsContact CB-CG2 3.49Å
250	V	84.4	Confident	87.3	Confident	6 Å²	6	28.9 Å²	28.9	4%	0.036	18%	0.175	C	C	.	.	H	α-helix	trans	-105.3	-44.6	170.9	-176.1	0	0	0	0	110.1	P146 S247 P248 S254 P461 A463 A504 A508	P146-V250 HydrophobicContact CB-CG2 4.45Å; P146-V250 HydrophobicContact CG-CG2 4.13Å; S247-V250 PolarHBondContact O-N 3.42Å; P248-V250 PolarHBondContact O-N 3.32Å; P248-V250 VanDerWaalsContact O-N 3.12Å; V250-S254 PolarHBondContact O-OG 2.89Å; V250-S254 VanDerWaalsContact O-OG 3.11Å; V250-P461 HydrophobicContact CB-CB 3.91Å; V250-P461 HydrophobicContact CB-CG 4.44Å; V250-P461 HydrophobicContact CG1-CB 3.76Å; V250-P461 HydrophobicContact CG1-CG 4.06Å; V250-P461 HydrophobicContact CG2-CB 4.44Å; V250-A463 HydrophobicContact CG2-CB 4.08Å; V250-A504 HydrophobicContact CG2-CB 4.29Å; V250-A508 HydrophobicContact CG1-CB 3.94Å
251	V	87.1	Confident	86.8	Confident	4 Å²	4	30.2 Å²	30.2	2%	0.024	19%	0.189	C	C	.	.	H	α-helix	trans	-69	-51.4	-176.7	176.6	0	0	0	0	112.5	V246 S247 P248 S254 M255 A458 P461 I511	V246-V251 HydrophobicContact CG1-CB 4.48Å; V246-V251 HydrophobicContact CG1-CG2 3.54Å; S247-V251 PolarHBondContact O-N 2.95Å; S247-V251 VanDerWaalsContact O-N 3.09Å; P248-V251 PolarHBondContact O-N 3.2Å; V251-S254 PolarHBondContact O-N 3.49Å; V251-M255 HydrophobicContact CG1-CE 4.05Å; V251-M255 HydrophobicContact CG1-CG 3.81Å; V251-M255 VanDerWaalsContact O-CG 3.32Å; V251-M255 WeakPolarHBondContact O-CG 3.18Å; V251-M255 PolarHBondContact O-N 3.13Å; V251-A458 WeakPolarHBondContact CG2-O 3.31Å; V251-P461 HydrophobicContact CG2-CG 3.86Å; V251-I511 HydrophobicContact CG2-CD1 4.31Å
252	V	83.9	Confident	86.3	Confident	45 Å²	45	29.6 Å²	29.6	27%	0.273	19%	0.191	S	C	.	.	H	α-helix	trans	-60.1	-49.5	-172.7	175	0	0	0	0	112.3	P248 S254 M255 L256 M274	P248-V252 HydrophobicContact CB-CG2 3.85Å; P248-V252 VanDerWaalsContact O-CB 3.24Å; P248-V252 WeakPolarHBondContact O-CB 3.26Å; P248-V252 WeakPolarHBondContact O-CG2 3.01Å; P248-V252 PolarHBondContact O-N 3.32Å; V252-S254 VanDerWaalsContact C-N 3.29Å; V252-S254 PolarHBondContact O-N 3.49Å; V252-M255 PolarHBondContact O-N 2.84Å; V252-L256 HydrophobicContact CG1-CD1 3.93Å; V252-L256 HydrophobicContact CG1-CG 4.28Å; V252-L256 WeakPolarHBondContact O-CG 3.31Å; V252-L256 PolarHBondContact O-N 3.49Å; V252-M274 HydrophobicContact CG1-SD 3.95Å; V252-M274 HydrophobicContact CG2-CG 4.11Å
253	P	80	Confident	86.1	Confident	64 Å²	64	32.3 Å²	32.3	42%	0.416	20%	0.201	S	C	.	.	H	α-helix	trans	-59.5	-39.6	177.2	-24	35.3	0	0	0	112.7	P248 I257	P248-P253 WeakPolarHBondContact O-CD 3.39Å; P253-I257 WeakPolarHBondContact O-CD1 3.4Å; P253-I257 VanDerWaalsContact O-CG1 3.28Å; P253-I257 WeakPolarHBondContact O-CG1 3.44Å; P253-I257 PolarHBondContact O-N 3.03Å; P253-I257 VanDerWaalsContact O-N 3.1Å
254	S	84.9	Confident	85.6	Confident	14 Å²	14	32.4 Å²	32.4	10%	0.098	20%	0.202	C	C	.	.	H	α-helix	trans	-68.6	-37.6	177.3	-57.7	0	0	0	0	112.7	V250 V251 V252 I257 L258	V250-S254 PolarHBondContact O-OG 2.89Å; V250-S254 VanDerWaalsContact O-OG 3.11Å; V251-S254 PolarHBondContact O-N 3.49Å; V252-S254 VanDerWaalsContact C-N 3.29Å; V252-S254 PolarHBondContact O-N 3.49Å; S254-I257 PolarHBondContact O-N 2.86Å; S254-L258 WeakPolarHBondContact O-CG 3.46Å; S254-L258 PolarHBondContact O-N 3.27Å; S254-L258 VanDerWaalsContact O-N 3.08Å
255	M	88.3	Confident	85.2	Confident	0 Å²	0	35.4 Å²	35.4	0%	0	22%	0.221	C	C	.	.	H	α-helix	trans	-67.2	-40.3	175.1	-69.7	-50.2	140.5	0	0	112.2	V251 V252 L258 Q259 P270 L273 M274 F454 A458 I511	V251-M255 HydrophobicContact CG1-CE 4.05Å; V251-M255 HydrophobicContact CG1-CG 3.81Å; V251-M255 VanDerWaalsContact O-CG 3.32Å; V251-M255 WeakPolarHBondContact O-CG 3.18Å; V251-M255 PolarHBondContact O-N 3.13Å; V252-M255 PolarHBondContact O-N 2.84Å; M255-L258 PolarHBondContact O-N 2.91Å; M255-L258 HydrophobicContact SD-CD1 4.31Å; M255-Q259 WeakPolarHBondContact O-CB 3.33Å; M255-Q259 PolarHBondContact O-N 3.21Å; M255-P270 HydrophobicContact CB-CB 4.05Å; M255-P270 HydrophobicContact SD-CB 4.35Å; M255-L273 HydrophobicContact CE-CD1 3.67Å; M255-L273 HydrophobicContact CG-CB 4.26Å; M255-L273 HydrophobicContact SD-CB 4.23Å; M255-L273 HydrophobicContact SD-CD1 3.5Å; M255-L273 VanDerWaalsContact SD-CD1 3.5Å; M255-M274 HydrophobicContact CB-CE 4.49Å; M255-M274 HydrophobicContact CB-CG 3.85Å; M255-M274 HydrophobicContact CB-SD 3.93Å; M255-M274 HydrophobicContact CG-CG 4.19Å; M255-F454 HydrophobicContact CE-CE1 4.05Å; M255-F454 HydrophobicContact CE-CZ 3.76Å; M255-F454 HydrophobicContact SD-CE1 4.18Å; M255-F454 HydrophobicContact SD-CZ 4.16Å; M255-A458 HydrophobicContact CE-CB 3.7Å; M255-I511 HydrophobicContact CE-CD1 4.24Å; M255-I511 HydrophobicContact CE-CG1 4.34Å; M255-I511 HydrophobicContact CE-CG2 3.78Å
256	L	84.3	Confident	84.8	Confident	90 Å²	90	41.5 Å²	41.5	47%	0.471	25%	0.249	S	C	.	.	H	α-helix	trans	-64.4	-39.4	175.4	-68.7	173.9	0	0	0	112.1	V252 Q259 A260 M274	V252-L256 HydrophobicContact CG1-CD1 3.93Å; V252-L256 HydrophobicContact CG1-CG 4.28Å; V252-L256 WeakPolarHBondContact O-CG 3.31Å; V252-L256 PolarHBondContact O-N 3.49Å; L256-Q259 PolarHBondContact O-N 3.04Å; L256-A260 WeakPolarHBondContact O-CB 3.37Å; L256-A260 PolarHBondContact O-N 2.85Å; L256-M274 HydrophobicContact CD2-CE 4.24Å; L256-M274 HydrophobicContact CD2-SD 4.06Å; L256-M274 HydrophobicContact CG-SD 4.17Å
257	I	84.3	Confident	84.4	Confident	107 Å²	107	44.7 Å²	44.7	55%	0.549	26%	0.263	S	S	.	.	H	α-helix	trans	-62.7	-43.2	173.8	-69.5	164	0	0	0	111.1	P253 S254 G261	P253-I257 WeakPolarHBondContact O-CD1 3.4Å; P253-I257 VanDerWaalsContact O-CG1 3.28Å; P253-I257 WeakPolarHBondContact O-CG1 3.44Å; P253-I257 PolarHBondContact O-N 3.03Å; P253-I257 VanDerWaalsContact O-N 3.1Å; S254-I257 PolarHBondContact O-N 2.86Å; I257-G261 PolarHBondContact O-N 3.14Å
258	L	87.2	Confident	84.2	Confident	11 Å²	11	45.7 Å²	45.7	6%	0.058	27%	0.273	C	S	.	.	H	α-helix	trans	-66.3	-41.9	177.3	-71.6	170.8	0	0	0	112	S254 M255 G261 G262 Y263 F454 I511 P516 L519	S254-L258 WeakPolarHBondContact O-CG 3.46Å; S254-L258 PolarHBondContact O-N 3.27Å; S254-L258 VanDerWaalsContact O-N 3.08Å; M255-L258 PolarHBondContact O-N 2.91Å; M255-L258 HydrophobicContact SD-CD1 4.31Å; L258-G261 CarbonylContact O-C 3.54Å; L258-G261 WeakPolarHBondContact O-CA 3.16Å; L258-G261 PolarHBondContact O-N 3.31Å; L258-G262 PolarHBondContact O-N 3.38Å; L258-Y263 HydrophobicContact CD2-CD2 4.17Å; L258-Y263 HydrophobicContact CD2-CG 4.3Å; L258-Y263 WeakPolarHBondContact O-CB 3.23Å; L258-Y263 PolarHBondContact O-N 3.47Å; L258-F454 HydrophobicContact CD1-CE1 4.5Å; L258-F454 HydrophobicContact CD1-CE2 4.09Å; L258-F454 HydrophobicContact CD1-CZ 3.53Å; L258-I511 HydrophobicContact CD1-CG2 3.94Å; L258-P516 HydrophobicContact CD2-CG 4.25Å; L258-L519 HydrophobicContact CD1-CD1 4.17Å
259	Q	83.8	Confident	84.7	Confident	74 Å²	74	44.1 Å²	44.1	35%	0.346	26%	0.263	S	S	.	.	H	α-helix	trans	-62.8	-44.8	176.3	-178.8	173.5	-24.1	0	0	111.8	M255 L256 G261 G262 V265 P270	M255-Q259 WeakPolarHBondContact O-CB 3.33Å; M255-Q259 PolarHBondContact O-N 3.21Å; L256-Q259 PolarHBondContact O-N 3.04Å; Q259-G261 VanDerWaalsContact C-N 3.26Å; Q259-G261 PolarHBondContact O-N 3.05Å; Q259-G262 PolarHBondContact O-N 3.38Å; Q259-V265 HydrophobicContact CB-CG2 4.44Å; Q259-V265 HydrophobicContact CG-CG2 4.09Å; Q259-P270 HydrophobicContact CB-CB 4.19Å; Q259-P270 HydrophobicContact CB-CG 4.28Å
260	A	83.8	Confident	85	Confident	87 Å²	87	42.2 Å²	42.2	72%	0.719	25%	0.247	S	C	*	.	H	α-helix	trans	-63.5	-30.7	173.7	0	0	0	0	0	112.7	L256 G262	L256-A260 WeakPolarHBondContact O-CB 3.37Å; L256-A260 PolarHBondContact O-N 2.85Å; A260-G262 PolarHBondContact O-N 3.5Å
261	G	85.3	Confident	85	Confident	28 Å²	28	45 Å²	45	29%	0.289	27%	0.265	S	S	.	.	T	Hydrogen-bonded Turn	trans	-77.5	-0.7	171.3	0	0	0	0	0	115.1	I257 L258 Q259 Y263 K521	I257-G261 PolarHBondContact O-N 3.14Å; L258-G261 CarbonylContact O-C 3.54Å; L258-G261 WeakPolarHBondContact O-CA 3.16Å; L258-G261 PolarHBondContact O-N 3.31Å; Q259-G261 VanDerWaalsContact C-N 3.26Å; Q259-G261 PolarHBondContact O-N 3.05Å; G261-Y263 VanDerWaalsContact C-N 3.33Å; G261-Y263 WeakPolarHBondContact O-CD2 3.37Å; G261-K521 WeakPolarHBondContact O-CE 3.38Å
262	G	85.6	Confident	84.9	Confident	17 Å²	17	45.3 Å²	45.3	18%	0.175	27%	0.266	C	S	.	.	T	Hydrogen-bonded Turn	trans	77.2	9.8	-177	0	0	0	0	0	115	L258 Q259 A260 K521 A522	L258-G262 PolarHBondContact O-N 3.38Å; Q259-G262 PolarHBondContact O-N 3.38Å; A260-G262 PolarHBondContact O-N 3.5Å; G262-K521 WeakPolarHBondContact O-CA 3.45Å; G262-A522 PolarHBondContact O-N 2.93Å
263	Y	89	Confident	85.1	Confident	58 Å²	58	43.2 Å²	43.2	23%	0.227	25%	0.253	C	S	.	.	B	Isolated β-bridge	trans	-83.7	121.5	-175.2	-66	-80.5	0	0	0	112.5	L258 G261 V265 P270 P516 L519 K521	L258-Y263 HydrophobicContact CD2-CD2 4.17Å; L258-Y263 HydrophobicContact CD2-CG 4.3Å; L258-Y263 WeakPolarHBondContact O-CB 3.23Å; L258-Y263 PolarHBondContact O-N 3.47Å; G261-Y263 VanDerWaalsContact C-N 3.33Å; G261-Y263 WeakPolarHBondContact O-CD2 3.37Å; Y263-V265 PolarHBondContact O-N 2.86Å; Y263-P270 WeakPolarHBondContact O-CG 3.42Å; Y263-P516 HydrophobicContact CE1-CB 4.05Å; Y263-L519 HydrophobicContact CD1-CB 4.5Å; Y263-K521 HydrophobicContact CD1-CB 4.05Å; Y263-K521 HydrophobicContact CD1-CG 4.46Å; Y263-K521 HydrophobicContact CE1-CB 3.96Å; Y263-K521 HydrophobicContact CE1-CD 4.43Å; Y263-K521 HydrophobicContact CE1-CG 4.29Å
264	G	85.3	Confident	85.3	Confident	2 Å²	2	41.8 Å²	41.8	2%	0.021	24%	0.241	C	C	.	.	T	Hydrogen-bonded Turn	trans	71.5	10.9	175.3	0	0	0	0	0	114.7	G268 V269 P270 Q520	G264-G268 PolarHBondContact O-N 2.99Å; G264-V269 PolarHBondContact O-N 3.39Å; G264-P270 WeakPolarHBondContact O-CD 3.32Å; G264-Q520 PolarHBondContact N-O 3.08Å
265	V	84.7	Confident	85.1	Confident	63 Å²	63	42.1 Å²	42.1	38%	0.382	25%	0.245	S	C	.	.	T	Hydrogen-bonded Turn	trans	-69.8	-42.7	-174.5	-178.6	0	0	0	0	111.7	Q259 Y263 K267 G268	Q259-V265 HydrophobicContact CB-CG2 4.44Å; Q259-V265 HydrophobicContact CG-CG2 4.09Å; Y263-V265 PolarHBondContact O-N 2.86Å; V265-K267 VanDerWaalsContact C-N 3.27Å; V265-K267 PolarHBondContact O-N 2.71Å; V265-G268 WeakPolarHBondContact O-CA 3.33Å; V265-G268 PolarHBondContact O-N 3.47Å
266	E	82.9	Confident	85	Confident	127 Å²	127	42.1 Å²	42.1	59%	0.593	25%	0.245	S	C	*	.	T	Hydrogen-bonded Turn	trans	-54.3	-41.1	179.4	-65.8	175	-179	0	0	113	A522	E266-A522 HydrophobicContact CG-CB 4.2Å; E266-A522 WeakPolarHBondContact OE1-CA 3.44Å
267	K	81.8	Confident	85.1	Confident	69 Å²	69	38.1 Å²	38.1	30%	0.3	23%	0.225	S	C	.	.	T	Hydrogen-bonded Turn	trans	-95.1	6.1	176.6	-56.5	-161.1	-168	179.2	0	113.9	V265 V269 G446 F447 N448 E451	V265-K267 VanDerWaalsContact C-N 3.27Å; V265-K267 PolarHBondContact O-N 2.71Å; K267-V269 VanDerWaalsContact C-N 3.28Å; K267-V269 HydrophobicContact CB-CG2 4.3Å; K267-V269 PolarHBondContact O-N 2.68Å; K267-G446 PolarHBondContact NZ-O 3.17Å; K267-F447 HydrophobicContact CB-CD1 4.32Å; K267-F447 HydrophobicContact CB-CE1 3.94Å; K267-F447 HydrophobicContact CD-CD1 4.13Å; K267-N448 PolarHBondContact NZ-ND2 3.39Å; K267-N448 PolarHBondContact NZ-OD1 3.24Å; K267-E451 WeakPolarHBondContact CD-OE1 3.4Å; K267-E451 WeakPolarHBondContact CD-OE2 3.36Å; K267-E451 WeakPolarHBondContact CE-OE1 3.48Å; K267-E451 WeakPolarHBondContact CE-OE2 3.26Å; K267-E451 IonicContact NZ-OE1 2.81Å; K267-E451 IonicContact NZ-OE2 3.78Å; K267-E451 PolarHBondContact NZ-OE2 2.93Å
268	G	83.8	Confident	84.9	Confident	21 Å²	21	34.6 Å²	34.6	22%	0.216	21%	0.21	C	C	.	.	T	Hydrogen-bonded Turn	trans	60.7	28.3	178.7	0	0	0	0	0	115	G264 V265 T271 L272	G264-G268 PolarHBondContact O-N 2.99Å; V265-G268 WeakPolarHBondContact O-CA 3.33Å; V265-G268 PolarHBondContact O-N 3.47Å; G268-T271 PolarHBondContact O-N 3.07Å; G268-L272 WeakPolarHBondContact O-CB 3.33Å; G268-L272 PolarHBondContact O-N 2.82Å
269	V	88.3	Confident	84.7	Confident	0 Å²	0	35 Å²	35	0%	0	21%	0.212	C	C	.	.	H	α-helix	trans	-59.7	-48	-176.7	177.6	0	0	0	0	112.2	G264 K267 T271 L272 L273 F447 F454 V455 L519	G264-V269 PolarHBondContact O-N 3.39Å; K267-V269 VanDerWaalsContact C-N 3.28Å; K267-V269 HydrophobicContact CB-CG2 4.3Å; K267-V269 PolarHBondContact O-N 2.68Å; V269-T271 PolarHBondContact O-N 2.99Å; V269-L272 PolarHBondContact O-N 3.47Å; V269-L273 HydrophobicContact CG1-CD1 3.71Å; V269-L273 HydrophobicContact CG1-CG 4.39Å; V269-L273 WeakPolarHBondContact O-CB 3.34Å; V269-L273 VanDerWaalsContact O-CG 3.29Å; V269-L273 WeakPolarHBondContact O-CG 3.24Å; V269-L273 PolarHBondContact O-N 3.29Å; V269-F447 HydrophobicContact CG2-CD1 3.85Å; V269-F447 HydrophobicContact CG2-CE1 3.42Å; V269-F447 VanDerWaalsContact CG2-CE1 3.42Å; V269-F447 HydrophobicContact CG2-CZ 4.24Å; V269-F454 HydrophobicContact CG1-CD1 3.91Å; V269-F454 HydrophobicContact CG1-CE1 4.05Å; V269-V455 HydrophobicContact CG1-CG2 3.7Å; V269-L519 HydrophobicContact CB-CD2 4.17Å; V269-L519 HydrophobicContact CG1-CD2 3.95Å; V269-L519 HydrophobicContact CG2-CD2 4.29Å
270	P	86.4	Confident	85	Confident	0 Å²	0	31.5 Å²	31.5	0%	0	20%	0.196	C	C	.	.	H	α-helix	trans	-58.4	-45.6	175	-24.5	35.9	0	0	0	112.3	M255 Q259 Y263 G264 L272 L273 M274	M255-P270 HydrophobicContact CB-CB 4.05Å; M255-P270 HydrophobicContact SD-CB 4.35Å; Q259-P270 HydrophobicContact CB-CB 4.19Å; Q259-P270 HydrophobicContact CB-CG 4.28Å; Y263-P270 WeakPolarHBondContact O-CG 3.42Å; G264-P270 WeakPolarHBondContact O-CD 3.32Å; P270-L272 PolarHBondContact O-N 2.82Å; P270-L273 PolarHBondContact O-N 3.45Å; P270-M274 HydrophobicContact CB-CE 4.44Å; P270-M274 VanDerWaalsContact O-CG 3.32Å; P270-M274 WeakPolarHBondContact O-CG 3.24Å; P270-M274 PolarHBondContact O-N 3.03Å
271	T	83.8	Confident	85.1	Confident	65 Å²	65	27.8 Å²	27.8	40%	0.399	16%	0.164	S	C	.	.	H	α-helix	trans	-62.3	-43.6	180	-45	0	0	0	0	112.4	G268 V269 A275	G268-T271 PolarHBondContact O-N 3.07Å; V269-T271 PolarHBondContact O-N 2.99Å; T271-A275 WeakPolarHBondContact O-CB 2.97Å; T271-A275 PolarHBondContact O-N 3.25Å
272	L	85.6	Confident	85	Confident	9 Å²	9	28.7 Å²	28.7	5%	0.047	16%	0.161	C	C	.	.	H	α-helix	trans	-63.1	-43.9	175.7	175.9	63.7	0	0	0	111.2	V205 C206 L209 G268 V269 P270 A275 A276 F447	V205-L272 HydrophobicContact CG1-CD1 4.2Å; V205-L272 HydrophobicContact CG1-CD2 3.85Å; C206-L272 HydrophobicContact CB-CD1 3.96Å; L209-L272 HydrophobicContact CD2-CD1 4.3Å; L209-L272 HydrophobicContact CD2-CD2 4.07Å; L209-L272 HydrophobicContact CD2-CG 3.87Å; G268-L272 WeakPolarHBondContact O-CB 3.33Å; G268-L272 PolarHBondContact O-N 2.82Å; V269-L272 PolarHBondContact O-N 3.47Å; P270-L272 PolarHBondContact O-N 2.82Å; L272-A275 PolarHBondContact O-N 3.25Å; L272-A276 WeakPolarHBondContact O-CB 3.22Å; L272-A276 PolarHBondContact O-N 2.95Å; L272-F447 HydrophobicContact CD2-CE2 3.66Å; L272-F447 HydrophobicContact CD2-CZ 3.6Å
273	L	88.4	Confident	85.1	Confident	1 Å²	1	29.3 Å²	29.3	1%	0.005	16%	0.161	C	C	.	.	H	α-helix	trans	-63.9	-42.8	179.3	-76	167	0	0	0	112.1	M255 V269 P270 G277 F454 V455 A458	M255-L273 HydrophobicContact CE-CD1 3.67Å; M255-L273 HydrophobicContact CG-CB 4.26Å; M255-L273 HydrophobicContact SD-CB 4.23Å; M255-L273 HydrophobicContact SD-CD1 3.5Å; M255-L273 VanDerWaalsContact SD-CD1 3.5Å; V269-L273 HydrophobicContact CG1-CD1 3.71Å; V269-L273 HydrophobicContact CG1-CG 4.39Å; V269-L273 WeakPolarHBondContact O-CB 3.34Å; V269-L273 VanDerWaalsContact O-CG 3.29Å; V269-L273 WeakPolarHBondContact O-CG 3.24Å; V269-L273 PolarHBondContact O-N 3.29Å; P270-L273 PolarHBondContact O-N 3.45Å; L273-G277 PolarHBondContact O-N 3.42Å; L273-F454 HydrophobicContact CD1-CD1 4.22Å; L273-F454 HydrophobicContact CD1-CE1 3.63Å; L273-V455 HydrophobicContact CD1-CG2 4.4Å; L273-V455 HydrophobicContact CD2-CB 4.38Å; L273-V455 HydrophobicContact CD2-CG1 3.9Å; L273-V455 HydrophobicContact CD2-CG2 4.37Å; L273-V455 HydrophobicContact CG-CG2 4.48Å; L273-A458 HydrophobicContact CD1-CB 4.01Å; L273-A458 HydrophobicContact CD2-CB 4.1Å
274	M	84.2	Confident	85.2	Confident	35 Å²	35	26.6 Å²	26.6	17%	0.172	15%	0.15	C	C	.	.	H	α-helix	trans	-65.8	-46.3	176.4	-67.3	-174.3	-69.4	0	0	111.5	V252 M255 L256 P270 S278	V252-M274 HydrophobicContact CG1-SD 3.95Å; V252-M274 HydrophobicContact CG2-CG 4.11Å; M255-M274 HydrophobicContact CB-CE 4.49Å; M255-M274 HydrophobicContact CB-CG 3.85Å; M255-M274 HydrophobicContact CB-SD 3.93Å; M255-M274 HydrophobicContact CG-CG 4.19Å; L256-M274 HydrophobicContact CD2-CE 4.24Å; L256-M274 HydrophobicContact CD2-SD 4.06Å; L256-M274 HydrophobicContact CG-SD 4.17Å; P270-M274 HydrophobicContact CB-CE 4.44Å; P270-M274 VanDerWaalsContact O-CG 3.32Å; P270-M274 WeakPolarHBondContact O-CG 3.24Å; P270-M274 PolarHBondContact O-N 3.03Å; M274-S278 PolarHBondContact O-N 2.97Å; M274-S278 PolarHBondContact O-OG 3.36Å; M274-S278 VanDerWaalsContact O-OG 3.12Å
275	A	80.4	Confident	85.2	Confident	21 Å²	21	26.7 Å²	26.7	17%	0.174	15%	0.15	C	C	.	.	H	α-helix	trans	-66.2	-45	179.4	0	0	0	0	0	112.8	T271 L272 S278 I279	T271-A275 WeakPolarHBondContact O-CB 2.97Å; T271-A275 PolarHBondContact O-N 3.25Å; L272-A275 PolarHBondContact O-N 3.25Å; A275-S278 PolarHBondContact O-N 3.45Å; A275-I279 PolarHBondContact O-N 3.48Å
276	A	86.9	Confident	85.3	Confident	0 Å²	0	25.1 Å²	25.1	0%	0	14%	0.14	C	C	.	.	H	α-helix	trans	-69.1	-37.4	179.8	0	0	0	0	0	111.8	C206 L209 S210 L272 S278 I279 D280 W459	C206-A276 VanDerWaalsContact SG-CA 3.54Å; L209-A276 HydrophobicContact CB-CB 4.25Å; L209-A276 HydrophobicContact CD2-CB 3.71Å; L209-A276 HydrophobicContact CG-CB 3.84Å; S210-A276 WeakPolarHBondContact OG-CA 3.22Å; S210-A276 WeakPolarHBondContact OG-CB 3.01Å; S210-A276 PolarHBondContact OG-O 3.32Å; S210-A276 VanDerWaalsContact OG-O 3.12Å; L272-A276 WeakPolarHBondContact O-CB 3.22Å; L272-A276 PolarHBondContact O-N 2.95Å; A276-S278 VanDerWaalsContact C-N 3.28Å; A276-S278 PolarHBondContact O-N 3.48Å; A276-I279 PolarHBondContact O-N 3.42Å; A276-I279 VanDerWaalsContact O-N 3.12Å; A276-D280 WeakPolarHBondContact O-CB 3.45Å; A276-D280 PolarHBondContact O-N 3.45Å; A276-W459 HydrophobicContact CB-CH2 4.14Å; A276-W459 HydrophobicContact CB-CZ2 3.69Å
277	G	86.6	Confident	85.6	Confident	6 Å²	6	19.5 Å²	19.5	6%	0.062	12%	0.117	C	C	.	.	H	α-helix	trans	-58.8	-39.2	173.8	0	0	0	0	0	112.4	L273 I279 D280 D281	L273-G277 PolarHBondContact O-N 3.42Å; G277-I279 VanDerWaalsContact C-N 3.34Å; G277-I279 PolarHBondContact O-N 3.26Å; G277-D280 PolarHBondContact O-N 3.42Å; G277-D281 PolarHBondContact O-N 3.49Å
278	S	80.1	Confident	86.1	Confident	32 Å²	32	16.2 Å²	16.2	22%	0.224	10%	0.103	C	C	.	.	H	α-helix	trans	-68.9	-28.1	176.1	-52.1	0	0	0	0	113.9	M274 A275 A276 I282	M274-S278 PolarHBondContact O-N 2.97Å; M274-S278 PolarHBondContact O-OG 3.36Å; M274-S278 VanDerWaalsContact O-OG 3.12Å; A275-S278 PolarHBondContact O-N 3.45Å; A276-S278 VanDerWaalsContact C-N 3.28Å; A276-S278 PolarHBondContact O-N 3.48Å; S278-I282 WeakPolarHBondContact O-CD1 3.25Å; S278-I282 VanDerWaalsContact O-CG1 3.29Å; S278-I282 WeakPolarHBondContact O-CG1 3.3Å; S278-I282 PolarHBondContact O-N 3.25Å
279	I	82.9	Confident	86.2	Confident	20 Å²	20	15.4 Å²	15.4	10%	0.103	9%	0.093	C	C	.	.	H	α-helix	trans	-78.7	-39.1	174.3	-58.8	173.5	0	0	0	111	L199 C206 S210 F211 A275 A276 G277 D281 I282 L283	L199-I279 HydrophobicContact CD1-CD1 3.52Å; L199-I279 HydrophobicContact CD1-CG1 3.66Å; C206-I279 VanDerWaalsContact SG-CD1 3.55Å; S210-I279 WeakPolarHBondContact OG-CB 3.14Å; F211-I279 HydrophobicContact CD2-CG2 4.46Å; F211-I279 HydrophobicContact CE2-CG2 3.94Å; A275-I279 PolarHBondContact O-N 3.48Å; A276-I279 PolarHBondContact O-N 3.42Å; A276-I279 VanDerWaalsContact O-N 3.12Å; G277-I279 VanDerWaalsContact C-N 3.34Å; G277-I279 PolarHBondContact O-N 3.26Å; I279-D281 VanDerWaalsContact C-N 3.34Å; I279-I282 PolarHBondContact O-N 3.15Å; I279-L283 WeakPolarHBondContact O-CB 3.45Å; I279-L283 PolarHBondContact O-N 3.41Å
280	D	88.8	Confident	86.1	Confident	0 Å²	0	16.8 Å²	16.8	0%	0	10%	0.102	C	C	.	.	H	α-helix	trans	-57	-46	172.6	178.9	103.2	0	0	0	110.7	C214 A245 V246 A276 G277 I282 L283 A284 R434 W459	C214-D280 WeakPolarHBondContact CB-OD1 3.42Å; A245-D280 VanDerWaalsContact CA-OD2 3.31Å; A245-D280 WeakPolarHBondContact CA-OD2 3.44Å; V246-D280 WeakPolarHBondContact CG2-OD2 3.49Å; V246-D280 PolarHBondContact N-OD2 3.47Å; A276-D280 WeakPolarHBondContact O-CB 3.45Å; A276-D280 PolarHBondContact O-N 3.45Å; G277-D280 PolarHBondContact O-N 3.42Å; D280-I282 PolarHBondContact O-N 3Å; D280-L283 PolarHBondContact O-N 2.85Å; D280-A284 VanDerWaalsContact O-CB 3.32Å; D280-A284 WeakPolarHBondContact O-CB 3.15Å; D280-A284 PolarHBondContact O-N 3.02Å; D280-R434 IonicContact OD1-CZ 3.33Å; D280-R434 IonicContact OD1-NH1 3.86Å; D280-R434 IonicContact OD1-NH2 2.73Å; D280-R434 PolarHBondContact OD1-NH2 2.9Å; D280-R434 IonicContact OD2-NH2 2.66Å; D280-R434 PolarHBondContact OD2-NH2 2.85Å; D280-W459 HydrophobicContact CB-CH2 3.75Å; D280-W459 HydrophobicContact CB-CZ3 4.2Å; D280-W459 VanDerWaalsContact OD1-CZ3 3.24Å; D280-W459 WeakPolarHBondContact OD1-CZ3 3.38Å
281	D	86.1	Confident	86.2	Confident	10 Å²	10	17.2 Å²	17.2	5%	0.053	11%	0.105	C	C	.	.	H	α-helix	trans	-56.7	-49.5	171.5	-77.9	14.7	0	0	0	112.5	V246 P248 G277 I279 L283 A284 I285 V465	V246-D281 VanDerWaalsContact O-OD1 3.12Å; P248-D281 WeakPolarHBondContact CD-OD2 3.27Å; P248-D281 WeakPolarHBondContact CG-OD2 3.44Å; G277-D281 PolarHBondContact O-N 3.49Å; I279-D281 VanDerWaalsContact C-N 3.34Å; D281-L283 VanDerWaalsContact C-N 3.32Å; D281-L283 PolarHBondContact O-N 2.86Å; D281-A284 PolarHBondContact O-N 3.39Å; D281-I285 HydrophobicContact CB-CD1 4.39Å; D281-I285 WeakPolarHBondContact O-CB 3.41Å; D281-I285 VanDerWaalsContact O-CD1 3.31Å; D281-I285 WeakPolarHBondContact O-CD1 3.33Å; D281-I285 VanDerWaalsContact O-CG1 3.23Å; D281-I285 WeakPolarHBondContact O-CG1 3.47Å; D281-I285 PolarHBondContact O-N 3.15Å; D281-V465 HydrophobicContact CB-CG2 4.39Å
282	I	82.6	Confident	86.4	Confident	46 Å²	46	14.1 Å²	14.1	24%	0.236	9%	0.086	C	C	.	.	H	α-helix	trans	-57.6	-47.4	177.5	-66.6	159.4	0	0	0	110.6	L194 S278 I279 D280 T286 L370	L194-I282 HydrophobicContact CD1-CD1 3.74Å; L194-I282 HydrophobicContact CD1-CG1 4.42Å; L194-I282 HydrophobicContact CD2-CD1 3.64Å; L194-I282 HydrophobicContact CG-CD1 4.34Å; S278-I282 WeakPolarHBondContact O-CD1 3.25Å; S278-I282 VanDerWaalsContact O-CG1 3.29Å; S278-I282 WeakPolarHBondContact O-CG1 3.3Å; S278-I282 PolarHBondContact O-N 3.25Å; I279-I282 PolarHBondContact O-N 3.15Å; D280-I282 PolarHBondContact O-N 3Å; I282-T286 VanDerWaalsContact O-CB 3.24Å; I282-T286 WeakPolarHBondContact O-CB 3.47Å; I282-T286 PolarHBondContact O-N 2.72Å; I282-T286 PolarHBondContact O-OG1 3.38Å; I282-L370 HydrophobicContact CG1-CD1 3.98Å; I282-L370 HydrophobicContact CG1-CD2 4.04Å
283	L	88.5	Confident	86.2	Confident	31 Å²	31	13.7 Å²	13.7	16%	0.162	8%	0.083	C	C	.	.	H	α-helix	trans	-62.4	-46.1	-178.7	176.5	60.1	0	0	0	111	F211 C214 I215 I279 D280 D281 T286 G287	F211-L283 HydrophobicContact CB-CD2 4.2Å; F211-L283 HydrophobicContact CD1-CD1 4.21Å; F211-L283 HydrophobicContact CD1-CD2 3.69Å; F211-L283 HydrophobicContact CD2-CD2 3.96Å; F211-L283 HydrophobicContact CE1-CD1 3.71Å; F211-L283 HydrophobicContact CE1-CD2 3.94Å; F211-L283 HydrophobicContact CE1-CG 4.43Å; F211-L283 HydrophobicContact CE2-CD2 4.17Å; F211-L283 HydrophobicContact CG-CD2 3.7Å; F211-L283 HydrophobicContact CZ-CD1 4Å; F211-L283 HydrophobicContact CZ-CD2 4.17Å; C214-L283 HydrophobicContact CB-CD2 3.91Å; I215-L283 HydrophobicContact CD1-CD2 4.46Å; I215-L283 HydrophobicContact CG1-CD2 4.25Å; I279-L283 WeakPolarHBondContact O-CB 3.45Å; I279-L283 PolarHBondContact O-N 3.41Å; D280-L283 PolarHBondContact O-N 2.85Å; D281-L283 VanDerWaalsContact C-N 3.32Å; D281-L283 PolarHBondContact O-N 2.86Å; L283-T286 PolarHBondContact O-N 3.25Å; L283-G287 PolarHBondContact O-N 3.2Å
284	A	91.6	Very high	86	Confident	0 Å²	0	15.5 Å²	15.5	0%	0	9%	0.093	C	C	.	.	H	α-helix	trans	-65.2	-46.4	179	0	0	0	0	0	112.3	A245 D280 D281 T286 G287 F288	A245-A284 HydrophobicContact CB-CB 3.65Å; D280-A284 VanDerWaalsContact O-CB 3.32Å; D280-A284 WeakPolarHBondContact O-CB 3.15Å; D280-A284 PolarHBondContact O-N 3.02Å; D281-A284 PolarHBondContact O-N 3.39Å; A284-T286 PolarHBondContact O-N 3.27Å; A284-G287 PolarHBondContact O-N 3.38Å; A284-F288 WeakPolarHBondContact O-CB 3.25Å; A284-F288 PolarHBondContact O-N 2.96Å
285	I	85.6	Confident	86	Confident	5 Å²	5	14.9 Å²	14.9	3%	0.026	9%	0.093	C	C	.	.	H	α-helix	trans	-64.4	-41.2	177.7	-68.4	158.1	0	0	0	110.9	L187 D281 N289 L370 V465	L187-I285 HydrophobicContact CD2-CD1 3.51Å; L187-I285 HydrophobicContact CD2-CG1 4.23Å; L187-I285 HydrophobicContact CD2-CG2 4.02Å; D281-I285 HydrophobicContact CB-CD1 4.39Å; D281-I285 WeakPolarHBondContact O-CB 3.41Å; D281-I285 VanDerWaalsContact O-CD1 3.31Å; D281-I285 WeakPolarHBondContact O-CD1 3.33Å; D281-I285 VanDerWaalsContact O-CG1 3.23Å; D281-I285 WeakPolarHBondContact O-CG1 3.47Å; D281-I285 PolarHBondContact O-N 3.15Å; I285-N289 WeakPolarHBondContact O-CB 3.21Å; I285-N289 PolarHBondContact O-N 2.97Å; I285-N289 PolarHBondContact O-ND2 3.44Å; I285-L370 HydrophobicContact CD1-CD1 4.39Å; I285-V465 HydrophobicContact CD1-CG1 4.36Å; I285-V465 HydrophobicContact CG1-CG1 3.94Å
286	T	86.1	Confident	86	Confident	29 Å²	29	14.6 Å²	14.6	18%	0.178	9%	0.088	C	C	.	.	H	α-helix	trans	-67.2	-46.3	177.8	-54.1	0	0	0	0	110.9	I282 L283 A284 N289 T290 V312 L367	I282-T286 VanDerWaalsContact O-CB 3.24Å; I282-T286 WeakPolarHBondContact O-CB 3.47Å; I282-T286 PolarHBondContact O-N 2.72Å; I282-T286 PolarHBondContact O-OG1 3.38Å; L283-T286 PolarHBondContact O-N 3.25Å; A284-T286 PolarHBondContact O-N 3.27Å; T286-N289 PolarHBondContact O-N 2.93Å; T286-T290 WeakPolarHBondContact O-CB 3.5Å; T286-T290 PolarHBondContact O-N 3.41Å; T286-T290 PolarHBondContact O-OG1 2.97Å; T286-V312 HydrophobicContact CG2-CG1 4.25Å; T286-V312 HydrophobicContact CG2-CG2 4.2Å; T286-L367 HydrophobicContact CG2-CD1 4.35Å; T286-L367 HydrophobicContact CG2-CD2 4.2Å; T286-L367 WeakPolarHBondContact OG1-CD1 3.49Å
287	G	90.1	Very high	85.5	Confident	10 Å²	10	15.1 Å²	15.1	10%	0.103	9%	0.091	C	C	.	.	H	α-helix	trans	-61.1	-47.6	177	0	0	0	0	0	112.6	L283 A284 N289 T290 C291	L283-G287 PolarHBondContact O-N 3.2Å; A284-G287 PolarHBondContact O-N 3.38Å; G287-N289 PolarHBondContact O-N 3.36Å; G287-T290 WeakPolarHBondContact O-CB 3.32Å; G287-T290 PolarHBondContact O-N 3.45Å; G287-C291 PolarHBondContact O-N 3.46Å; G287-C291 PolarHBondContact O-SG 3.28Å; G287-C291 VanDerWaalsContact O-SG 3.38Å
288	F	91.3	Very high	84.3	Confident	0 Å²	0	20.5 Å²	20.5	0%	0	13%	0.128	C	C	.	.	H	α-helix	trans	-53.4	-52.8	173.4	171	-90	0	0	0	111.6	I238 F241 V242 A284 T290 C291 L292 I469 L472 A473	I238-F288 HydrophobicContact CG2-CD2 3.91Å; I238-F288 HydrophobicContact CG2-CE2 3.56Å; F241-F288 HydrophobicContact CB-CB 3.89Å; V242-F288 HydrophobicContact CG2-CD2 3.59Å; V242-F288 HydrophobicContact CG2-CE2 3.64Å; A284-F288 WeakPolarHBondContact O-CB 3.25Å; A284-F288 PolarHBondContact O-N 2.96Å; F288-T290 VanDerWaalsContact C-N 3.31Å; F288-T290 PolarHBondContact O-N 2.98Å; F288-C291 PolarHBondContact O-N 3.4Å; F288-L292 HydrophobicContact CE1-CB 4.48Å; F288-L292 HydrophobicContact CE1-CD2 4.01Å; F288-L292 HydrophobicContact CZ-CD2 4.43Å; F288-L292 WeakPolarHBondContact O-CB 3.49Å; F288-L292 PolarHBondContact O-N 2.93Å; F288-I469 HydrophobicContact CB-CD1 3.7Å; F288-I469 HydrophobicContact CD1-CB 3.87Å; F288-I469 HydrophobicContact CD1-CD1 4.11Å; F288-I469 HydrophobicContact CD1-CG2 4Å; F288-I469 HydrophobicContact CD2-CB 4.3Å; F288-I469 HydrophobicContact CD2-CD1 3.76Å; F288-I469 HydrophobicContact CD2-CG1 4.45Å; F288-I469 HydrophobicContact CE1-CB 3.81Å; F288-I469 HydrophobicContact CE1-CG2 4.12Å; F288-I469 HydrophobicContact CE2-CB 4.17Å; F288-I469 HydrophobicContact CE2-CD1 4.39Å; F288-I469 WeakPolarHBondContact CE2-O 3.28Å; F288-I469 HydrophobicContact CG-CB 4.14Å; F288-I469 HydrophobicContact CG-CD1 3.57Å; F288-I469 HydrophobicContact CG-CG1 4.41Å; F288-I469 HydrophobicContact CZ-CB 3.96Å; F288-I469 WeakPolarHBondContact CZ-O 3.49Å; F288-L472 HydrophobicContact CE1-CB 4.27Å; F288-L472 HydrophobicContact CE1-CD2 4Å; F288-L472 HydrophobicContact CE1-CG 4.31Å; F288-L472 HydrophobicContact CZ-CB 4.18Å; F288-A473 HydrophobicContact CE2-CB 4.31Å; F288-A473 HydrophobicContact CZ-CB 4.15Å
289	N	85.6	Confident	83.6	Confident	3 Å²	3	21.4 Å²	21.4	2%	0.016	14%	0.142	C	C	.	.	H	α-helix	trans	-63.9	-36.5	-178.5	-80.2	-35.5	0	0	0	112.3	I285 T286 G287 L292 G293 G363	I285-N289 WeakPolarHBondContact O-CB 3.21Å; I285-N289 PolarHBondContact O-N 2.97Å; I285-N289 PolarHBondContact O-ND2 3.44Å; T286-N289 PolarHBondContact O-N 2.93Å; G287-N289 PolarHBondContact O-N 3.36Å; N289-L292 PolarHBondContact O-N 3.5Å; N289-G293 PolarHBondContact O-N 2.94Å; N289-G363 VanDerWaalsContact CB-O 3.26Å; N289-G363 WeakPolarHBondContact CB-O 3.33Å; N289-G363 PolarHBondContact ND2-O 3.3Å
290	T	85.9	Confident	83.3	Confident	30 Å²	30	24.1 Å²	24.1	18%	0.184	16%	0.163	C	C	.	.	H	α-helix	trans	-62	-48	173.4	-48.6	0	0	0	0	110.6	T286 G287 F288 L292 G293 M294 V312	T286-T290 WeakPolarHBondContact O-CB 3.5Å; T286-T290 PolarHBondContact O-N 3.41Å; T286-T290 PolarHBondContact O-OG1 2.97Å; G287-T290 WeakPolarHBondContact O-CB 3.32Å; G287-T290 PolarHBondContact O-N 3.45Å; F288-T290 VanDerWaalsContact C-N 3.31Å; F288-T290 PolarHBondContact O-N 2.98Å; T290-L292 VanDerWaalsContact C-N 3.33Å; T290-L292 PolarHBondContact O-N 3.33Å; T290-G293 PolarHBondContact O-N 3.35Å; T290-M294 HydrophobicContact CG2-CE 4.3Å; T290-M294 WeakPolarHBondContact O-CG 3.25Å; T290-M294 PolarHBondContact O-N 3.36Å; T290-V312 HydrophobicContact CG2-CG2 4.29Å; T290-V312 WeakPolarHBondContact OG1-CG2 3.33Å
291	C	89.4	Confident	82.7	Confident	8 Å²	8	29.6 Å²	29.6	5%	0.054	20%	0.197	C	C	.	.	H	α-helix	trans	-67.8	-31.8	178.6	-66.7	0	0	0	0	112.9	F237 I238 G287 F288 M294 A295	F237-C291 HydrophobicContact CB-CB 4.43Å; I238-C291 HydrophobicContact CG1-CB 3.67Å; G287-C291 PolarHBondContact O-N 3.46Å; G287-C291 PolarHBondContact O-SG 3.28Å; G287-C291 VanDerWaalsContact O-SG 3.38Å; F288-C291 PolarHBondContact O-N 3.4Å; C291-M294 HydrophobicContact CB-CE 4.27Å; C291-M294 PolarHBondContact O-N 3.06Å; C291-A295 WeakPolarHBondContact O-CB 3.46Å; C291-A295 PolarHBondContact O-N 3.35Å
292	L	86.9	Confident	82.3	Confident	0 Å²	0	35.7 Å²	35.7	0%	0	23%	0.229	C	C	.	.	H	α-helix	trans	-64.9	-50.4	173.2	-170.5	71.2	0	0	0	111.3	I238 F288 N289 T290 M294 A295 F296 P362 L472 A473	I238-L292 HydrophobicContact CD1-CD1 4.29Å; F288-L292 HydrophobicContact CE1-CB 4.48Å; F288-L292 HydrophobicContact CE1-CD2 4.01Å; F288-L292 HydrophobicContact CZ-CD2 4.43Å; F288-L292 WeakPolarHBondContact O-CB 3.49Å; F288-L292 PolarHBondContact O-N 2.93Å; N289-L292 PolarHBondContact O-N 3.5Å; T290-L292 VanDerWaalsContact C-N 3.33Å; T290-L292 PolarHBondContact O-N 3.33Å; L292-M294 VanDerWaalsContact C-N 3.26Å; L292-M294 PolarHBondContact O-N 3.08Å; L292-A295 PolarHBondContact O-N 3.43Å; L292-A295 VanDerWaalsContact O-N 3.11Å; L292-F296 HydrophobicContact CD1-CD2 3.83Å; L292-F296 HydrophobicContact CD1-CE2 3.62Å; L292-F296 HydrophobicContact CG-CD2 4.25Å; L292-F296 WeakPolarHBondContact O-CD2 3.37Å; L292-F296 PolarHBondContact O-N 3.04Å; L292-F296 VanDerWaalsContact O-N 3.09Å; L292-P362 HydrophobicContact CD2-CB 4.33Å; L292-L472 HydrophobicContact CD2-CD2 4.28Å; L292-L472 HydrophobicContact CD2-CG 4.05Å; L292-A473 HydrophobicContact CD1-CB 4Å
293	G	82.4	Confident	82.2	Confident	0 Å²	0	39.5 Å²	39.5	0%	0	24%	0.241	C	C	.	.	H	α-helix	trans	-59.1	-36.4	175.3	0	0	0	0	0	113	N289 T290 S297 R307 E311	N289-G293 PolarHBondContact O-N 2.94Å; T290-G293 PolarHBondContact O-N 3.35Å; G293-S297 WeakPolarHBondContact O-CB 3.48Å; G293-S297 PolarHBondContact O-OG 3.28Å; G293-R307 PolarHBondContact O-NH1 2.9Å; G293-E311 WeakPolarHBondContact CA-OE1 3.16Å
294	M	84	Confident	81.7	Confident	40 Å²	40	39.2 Å²	39.2	20%	0.197	24%	0.24	C	C	.	.	H	α-helix	trans	-67.7	-42.3	171.9	-71.1	-168.7	-66.5	0	0	113.1	T290 C291 L292 F296 S297 N304 V305	T290-M294 HydrophobicContact CG2-CE 4.3Å; T290-M294 WeakPolarHBondContact O-CG 3.25Å; T290-M294 PolarHBondContact O-N 3.36Å; C291-M294 HydrophobicContact CB-CE 4.27Å; C291-M294 PolarHBondContact O-N 3.06Å; L292-M294 VanDerWaalsContact C-N 3.26Å; L292-M294 PolarHBondContact O-N 3.08Å; M294-F296 VanDerWaalsContact C-N 3.35Å; M294-F296 PolarHBondContact O-N 3.1Å; M294-S297 WeakPolarHBondContact CA-OG 3.2Å; M294-S297 PolarHBondContact O-N 3.42Å; M294-S297 PolarHBondContact O-OG 3.48Å; M294-N304 WeakPolarHBondContact CG-O 3.38Å; M294-V305 HydrophobicContact SD-CB 4.5Å; M294-V305 HydrophobicContact SD-CG2 3.98Å
295	A	85	Confident	81.2	Confident	22 Å²	22	42.6 Å²	42.6	18%	0.182	26%	0.26	C	S	.	.	H	α-helix	trans	-65.9	-36.4	-178.5	0	0	0	0	0	112.7	Q234 I238 C291 L292	Q234-A295 HydrophobicContact CB-CB 4.08Å; I238-A295 HydrophobicContact CD1-CB 3.74Å; C291-A295 WeakPolarHBondContact O-CB 3.46Å; C291-A295 PolarHBondContact O-N 3.35Å; L292-A295 PolarHBondContact O-N 3.43Å; L292-A295 VanDerWaalsContact O-N 3.11Å
296	F	80.4	Confident	81	Confident	14 Å²	14	47.9 Å²	47.9	6%	0.061	29%	0.288	C	S	.	.	T	Hydrogen-bonded Turn	trans	-96.5	27.3	179	-69.3	-81.4	0	0	0	113.1	W235 L292 M294 R307 T476 A477 H480 L485	W235-F296 HydrophobicContact CH2-CE2 4.13Å; W235-F296 AromaticContact CH2-CZ 3.98Å; W235-F296 HydrophobicContact CH2-CZ 3.98Å; W235-F296 AromaticContact CZ2-CE2 3.96Å; W235-F296 HydrophobicContact CZ2-CE2 3.96Å; W235-F296 AromaticContact CZ2-CZ 3.74Å; W235-F296 HydrophobicContact CZ2-CZ 3.74Å; L292-F296 HydrophobicContact CD1-CD2 3.83Å; L292-F296 HydrophobicContact CD1-CE2 3.62Å; L292-F296 HydrophobicContact CG-CD2 4.25Å; L292-F296 WeakPolarHBondContact O-CD2 3.37Å; L292-F296 PolarHBondContact O-N 3.04Å; L292-F296 VanDerWaalsContact O-N 3.09Å; M294-F296 VanDerWaalsContact C-N 3.35Å; M294-F296 PolarHBondContact O-N 3.1Å; F296-R307 VanDerWaalsContact C-NH1 3.34Å; F296-R307 PolarHBondContact O-NH1 3.18Å; F296-T476 HydrophobicContact CD1-CG2 4.08Å; F296-T476 HydrophobicContact CD2-CG2 3.62Å; F296-T476 HydrophobicContact CE1-CG2 4.1Å; F296-T476 HydrophobicContact CE2-CG2 3.66Å; F296-T476 HydrophobicContact CG-CG2 3.85Å; F296-T476 HydrophobicContact CZ-CG2 3.9Å; F296-A477 HydrophobicContact CE1-CB 4.38Å; F296-A477 HydrophobicContact CZ-CB 3.95Å; F296-H480 AromaticContact CD1-CE1 3.58Å; F296-H480 AromaticContact CD1-CG 3.83Å; F296-H480 AromaticContact CD1-ND1 3.48Å; F296-H480 WeakPolarHBondContact CD1-ND1 3.46Å; F296-H480 AromaticContact CD1-NE2 3.97Å; F296-H480 HydrophobicContact CE1-CB 4.42Å; F296-H480 AromaticContact CE1-ND1 3.72Å; F296-L485 HydrophobicContact CD1-CD1 4.16Å; F296-L485 HydrophobicContact CE1-CB 4.47Å; F296-L485 HydrophobicContact CE1-CD1 3.61Å; F296-L485 HydrophobicContact CZ-CD1 4.34Å
297	S	75.3	Confident	80.8	Confident	11 Å²	11	48.4 Å²	48.4	8%	0.077	29%	0.286	C	S	.	.			trans	-108.5	121.3	178.4	57.7	0	0	0	0	113.5	G293 M294 G299 N304 R307	G293-S297 WeakPolarHBondContact O-CB 3.48Å; G293-S297 PolarHBondContact O-OG 3.28Å; M294-S297 WeakPolarHBondContact CA-OG 3.2Å; M294-S297 PolarHBondContact O-N 3.42Å; M294-S297 PolarHBondContact O-OG 3.48Å; S297-G299 PolarHBondContact O-N 3.06Å; S297-N304 PolarHBondContact O-ND2 3.17Å; S297-N304 PolarHBondContact O-OD1 3.34Å; S297-N304 VanDerWaalsContact OG-CA 3.29Å; S297-N304 WeakPolarHBondContact OG-CA 3.34Å; S297-N304 WeakPolarHBondContact OG-CB 3.33Å; S297-N304 PolarHBondContact OG-ND2 2.96Å; S297-N304 PolarHBondContact OG-OD1 3.44Å; S297-R307 VanDerWaalsContact CB-NH1 3.29Å
298	S	62.6	Low	80.4	Confident	120 Å²	120	47.9 Å²	47.9	84%	0.839	28%	0.281	S	S	*	.			trans	-89.1	100.8	177.5	-52.2	0	0	0	0	109.7
299	G	65.6	Low	80.1	Confident	50 Å²	50	52 Å²	52	52%	0.515	31%	0.306	S	S	.	.	S	Bend	trans	174	-168.5	-179.7	0	0	0	0	0	113.3	S297 N304	S297-G299 PolarHBondContact O-N 3.06Å; G299-N304 WeakPolarHBondContact CA-OD1 3.34Å; G299-N304 PolarHBondContact N-OD1 3.29Å; G299-N304 PolarHBondContact O-OD1 2.84Å
300	S	76.1	Confident	80.2	Confident	77 Å²	77	56 Å²	56	54%	0.538	33%	0.327	S	S	.	.			trans	-72.4	157.2	173	68.1	0	0	0	0	110.9	L302 Y303 N304	S300-L302 PolarHBondContact O-N 2.97Å; S300-Y303 WeakPolarHBondContact O-CA 3.44Å; S300-Y303 WeakPolarHBondContact O-CB 3.41Å; S300-Y303 PolarHBondContact O-N 3.27Å; S300-Y303 PolarHBondContact OG-N 3.05Å; S300-N304 PolarHBondContact O-N 3.09Å; S300-N304 PolarHBondContact O-OD1 3.16Å; S300-N304 VanDerWaalsContact O-OD1 3.14Å
301	T	74.9	Confident	80.2	Confident	116 Å²	116	54.6 Å²	54.6	71%	0.712	32%	0.319	S	S	*	.	H	α-helix	trans	-51.5	-36.3	179	-44	0	0	0	0	113	V305	T301-V305 WeakPolarHBondContact O-CG2 3.33Å; T301-V305 PolarHBondContact O-N 3.48Å; T301-V305 VanDerWaalsContact O-N 3.08Å
302	L	79.2	Confident	80.2	Confident	138 Å²	138	55.5 Å²	55.5	72%	0.723	32%	0.324	S	S	*	.	H	α-helix	trans	-70.1	-41.7	176.4	-176.1	63.7	0	0	0	112.5	S300 N304 L306	S300-L302 PolarHBondContact O-N 2.97Å; L302-N304 VanDerWaalsContact C-N 3.32Å; L302-L306 WeakPolarHBondContact O-CB 3.35Å; L302-L306 PolarHBondContact O-N 3.02Å
303	Y	80.1	Confident	80.4	Confident	126 Å²	126	58 Å²	58	49%	0.494	34%	0.344	S	S	.	.	H	α-helix	trans	-62.6	-41.3	174.2	176.2	-96.6	0	0	0	111.3	S300 L306 R307	S300-Y303 WeakPolarHBondContact O-CA 3.44Å; S300-Y303 WeakPolarHBondContact O-CB 3.41Å; S300-Y303 PolarHBondContact O-N 3.27Å; S300-Y303 PolarHBondContact OG-N 3.05Å; Y303-L306 PolarHBondContact O-N 3.11Å; Y303-R307 PolarHBondContact O-N 3.41Å
304	N	78.1	Confident	80.8	Confident	25 Å²	25	60.7 Å²	60.7	13%	0.134	36%	0.36	C	S	.	.	H	α-helix	trans	-63	-48	179.7	-68.8	18.6	0	0	0	111.1	M294 S297 G299 S300 L302 L306 R307 G308	M294-N304 WeakPolarHBondContact CG-O 3.38Å; S297-N304 PolarHBondContact O-ND2 3.17Å; S297-N304 PolarHBondContact O-OD1 3.34Å; S297-N304 VanDerWaalsContact OG-CA 3.29Å; S297-N304 WeakPolarHBondContact OG-CA 3.34Å; S297-N304 WeakPolarHBondContact OG-CB 3.33Å; S297-N304 PolarHBondContact OG-ND2 2.96Å; S297-N304 PolarHBondContact OG-OD1 3.44Å; G299-N304 WeakPolarHBondContact CA-OD1 3.34Å; G299-N304 PolarHBondContact N-OD1 3.29Å; G299-N304 PolarHBondContact O-OD1 2.84Å; S300-N304 PolarHBondContact O-N 3.09Å; S300-N304 PolarHBondContact O-OD1 3.16Å; S300-N304 VanDerWaalsContact O-OD1 3.14Å; L302-N304 VanDerWaalsContact C-N 3.32Å; N304-L306 PolarHBondContact O-N 2.89Å; N304-R307 PolarHBondContact O-N 3.11Å; N304-G308 PolarHBondContact O-N 2.99Å
305	V	80	Confident	81.2	Confident	70 Å²	70	58.8 Å²	58.8	42%	0.424	35%	0.351	S	S	.	.	H	α-helix	trans	-59.7	-44.2	173.2	171	0	0	0	0	111.4	M294 T301 R307 G308 V309	M294-V305 HydrophobicContact SD-CB 4.5Å; M294-V305 HydrophobicContact SD-CG2 3.98Å; T301-V305 WeakPolarHBondContact O-CG2 3.33Å; T301-V305 PolarHBondContact O-N 3.48Å; T301-V305 VanDerWaalsContact O-N 3.08Å; V305-R307 VanDerWaalsContact C-N 3.34Å; V305-R307 PolarHBondContact O-N 2.97Å; V305-G308 PolarHBondContact O-N 3.07Å; V305-V309 WeakPolarHBondContact O-CG2 3.48Å; V305-V309 PolarHBondContact O-N 3.46Å
306	L	83	Confident	81.6	Confident	117 Å²	117	61.8 Å²	61.8	61%	0.613	36%	0.363	S	S	*	.	H	α-helix	trans	-62.7	-39.4	178.2	-173.8	65.4	0	0	0	112	L302 Y303 N304 V309 L310	L302-L306 WeakPolarHBondContact O-CB 3.35Å; L302-L306 PolarHBondContact O-N 3.02Å; Y303-L306 PolarHBondContact O-N 3.11Å; N304-L306 PolarHBondContact O-N 2.89Å; L306-V309 PolarHBondContact O-N 3.16Å; L306-L310 VanDerWaalsContact O-CB 3.32Å; L306-L310 WeakPolarHBondContact O-CB 3.44Å; L306-L310 PolarHBondContact O-N 3.11Å
307	R	80.8	Confident	82.3	Confident	39 Å²	39	63.7 Å²	63.7	15%	0.147	38%	0.381	C	S	.	.	H	α-helix	trans	-66.5	-40.1	174.5	-178.2	166.2	174.4	-126.7	19.9	112.1	G293 F296 S297 Y303 N304 V305 V309 L310 E311 G360	G293-R307 PolarHBondContact O-NH1 2.9Å; F296-R307 VanDerWaalsContact C-NH1 3.34Å; F296-R307 PolarHBondContact O-NH1 3.18Å; S297-R307 VanDerWaalsContact CB-NH1 3.29Å; Y303-R307 PolarHBondContact O-N 3.41Å; N304-R307 PolarHBondContact O-N 3.11Å; V305-R307 VanDerWaalsContact C-N 3.34Å; V305-R307 PolarHBondContact O-N 2.97Å; R307-V309 PolarHBondContact O-N 3.11Å; R307-L310 WeakPolarHBondContact O-CB 3.44Å; R307-L310 PolarHBondContact O-N 2.98Å; R307-E311 IonicContact CZ-OE1 2.99Å; R307-E311 IonicContact NE-OE1 2.75Å; R307-E311 PolarHBondContact NE-OE1 2.93Å; R307-E311 PolarHBondContact O-N 3.22Å; R307-G360 PolarHBondContact NH2-O 2.84Å
308	G	81.6	Confident	83.2	Confident	0 Å²	0	64.8 Å²	64.8	0%	0	39%	0.391	C	S	.	.	H	α-helix	trans	-57.7	-46.8	172.9	0	0	0	0	0	112.4	N304 V305 E311 V312	N304-G308 PolarHBondContact O-N 2.99Å; V305-G308 PolarHBondContact O-N 3.07Å; G308-E311 PolarHBondContact O-N 3.39Å; G308-V312 WeakPolarHBondContact O-CG2 3.47Å; G308-V312 PolarHBondContact O-N 2.82Å
309	V	84.7	Confident	84.8	Confident	86 Å²	86	59.1 Å²	59.1	52%	0.521	35%	0.352	S	S	.	.	H	α-helix	trans	-65.5	-37.6	175.1	176.5	0	0	0	0	111.7	V305 L306 R307 V312 A313	V305-V309 WeakPolarHBondContact O-CG2 3.48Å; V305-V309 PolarHBondContact O-N 3.46Å; L306-V309 PolarHBondContact O-N 3.16Å; R307-V309 PolarHBondContact O-N 3.11Å; V309-V312 PolarHBondContact O-N 3.49Å; V309-A313 WeakPolarHBondContact O-CB 3.48Å; V309-A313 PolarHBondContact O-N 2.81Å
310	L	87.8	Confident	86.2	Confident	86 Å²	86	57.4 Å²	57.4	45%	0.45	33%	0.334	S	S	.	.	H	α-helix	trans	-65.1	-42	176.3	-177.2	63.7	0	0	0	112	L306 R307 V312 A313 V314	L306-L310 VanDerWaalsContact O-CB 3.32Å; L306-L310 WeakPolarHBondContact O-CB 3.44Å; L306-L310 PolarHBondContact O-N 3.11Å; R307-L310 WeakPolarHBondContact O-CB 3.44Å; R307-L310 PolarHBondContact O-N 2.98Å; L310-V312 VanDerWaalsContact C-N 3.31Å; L310-V312 PolarHBondContact O-N 3.44Å; L310-A313 PolarHBondContact O-N 2.84Å; L310-V314 HydrophobicContact CD1-CG2 4.17Å; L310-V314 HydrophobicContact CG-CG2 4.3Å; L310-V314 WeakPolarHBondContact O-CB 3.26Å; L310-V314 VanDerWaalsContact O-CG2 3.28Å; L310-V314 WeakPolarHBondContact O-CG2 3.42Å; L310-V314 PolarHBondContact O-N 3.32Å
311	E	87.4	Confident	87.2	Confident	2 Å²	2	59.5 Å²	59.5	1%	0.009	34%	0.338	C	S	.	.	H	α-helix	trans	-62	-38.8	175.9	-77.5	-171.4	-144.4	0	0	112.1	G293 R307 G308 G315 F361 G363 S364	G293-E311 WeakPolarHBondContact CA-OE1 3.16Å; R307-E311 IonicContact CZ-OE1 2.99Å; R307-E311 IonicContact NE-OE1 2.75Å; R307-E311 PolarHBondContact NE-OE1 2.93Å; R307-E311 PolarHBondContact O-N 3.22Å; G308-E311 PolarHBondContact O-N 3.39Å; E311-G315 PolarHBondContact O-N 3.02Å; E311-F361 HydrophobicContact CG-CB 3.99Å; E311-F361 HydrophobicContact CG-CD1 3.55Å; E311-F361 HydrophobicContact CG-CE1 4.49Å; E311-F361 HydrophobicContact CG-CG 4.22Å; E311-G363 WeakPolarHBondContact OE2-CA 3.26Å; E311-G363 PolarHBondContact OE2-N 3.5Å; E311-S364 WeakPolarHBondContact O-CB 3.44Å
312	V	87.6	Confident	88.2	Confident	27 Å²	27	56.3 Å²	56.3	16%	0.164	32%	0.317	C	S	.	.	H	α-helix	trans	-63.7	-47.8	172	171.6	0	0	0	0	111.1	T286 T290 G308 V309 L310 V314 G315 I316 L367	T286-V312 HydrophobicContact CG2-CG1 4.25Å; T286-V312 HydrophobicContact CG2-CG2 4.2Å; T290-V312 HydrophobicContact CG2-CG2 4.29Å; T290-V312 WeakPolarHBondContact OG1-CG2 3.33Å; G308-V312 WeakPolarHBondContact O-CG2 3.47Å; G308-V312 PolarHBondContact O-N 2.82Å; V309-V312 PolarHBondContact O-N 3.49Å; L310-V312 VanDerWaalsContact C-N 3.31Å; L310-V312 PolarHBondContact O-N 3.44Å; V312-V314 PolarHBondContact O-N 2.71Å; V312-G315 PolarHBondContact O-N 3.29Å; V312-I316 HydrophobicContact CG1-CD1 3.76Å; V312-I316 WeakPolarHBondContact O-CG1 3.28Å; V312-I316 PolarHBondContact O-N 3.12Å; V312-L367 HydrophobicContact CB-CD2 4.18Å; V312-L367 HydrophobicContact CG1-CD2 3.87Å; V312-L367 HydrophobicContact CG2-CD2 4.33Å
313	A	91	Very high	89	Confident	52 Å²	52	49.8 Å²	49.8	43%	0.43	28%	0.282	S	S	.	.	H	α-helix	trans	-62.4	-43.5	179.6	0	0	0	0	0	112.2	V309 L310 I316 A317	V309-A313 WeakPolarHBondContact O-CB 3.48Å; V309-A313 PolarHBondContact O-N 2.81Å; L310-A313 PolarHBondContact O-N 2.84Å; A313-I316 PolarHBondContact O-N 3.47Å; A313-A317 WeakPolarHBondContact O-CB 3.35Å; A313-A317 PolarHBondContact O-N 2.88Å
314	V	92.3	Very high	89.6	Confident	56 Å²	56	48.1 Å²	48.1	34%	0.339	28%	0.281	S	S	.	.	H	α-helix	trans	-63.8	-45.1	175.4	169.6	0	0	0	0	110.7	L310 V312 A317 A318	L310-V314 HydrophobicContact CD1-CG2 4.17Å; L310-V314 HydrophobicContact CG-CG2 4.3Å; L310-V314 WeakPolarHBondContact O-CB 3.26Å; L310-V314 VanDerWaalsContact O-CG2 3.28Å; L310-V314 WeakPolarHBondContact O-CG2 3.42Å; L310-V314 PolarHBondContact O-N 3.32Å; V312-V314 PolarHBondContact O-N 2.71Å; V314-A317 PolarHBondContact O-N 3.44Å; V314-A318 VanDerWaalsContact O-CB 3.23Å; V314-A318 WeakPolarHBondContact O-CB 3.35Å; V314-A318 PolarHBondContact O-N 3.21Å
315	G	92.1	Very high	90.4	Very high	0 Å²	0	51.3 Å²	51.3	0%	0	29%	0.294	C	S	.	.	H	α-helix	trans	-59.5	-47	176.8	0	0	0	0	0	112.6	E311 V312 G319 C368	E311-G315 PolarHBondContact O-N 3.02Å; V312-G315 PolarHBondContact O-N 3.29Å; G315-G319 PolarHBondContact O-N 3.46Å; G315-C368 VanDerWaalsContact O-CA 3.28Å; G315-C368 WeakPolarHBondContact O-CA 3.32Å
316	I	92.3	Very high	91	Very high	86 Å²	86	48 Å²	48	44%	0.441	27%	0.274	S	S	.	.	H	α-helix	trans	-66.1	-44.5	177.3	-66	168.3	0	0	0	111.3	V312 A313 G320 L367 V371	V312-I316 HydrophobicContact CG1-CD1 3.76Å; V312-I316 WeakPolarHBondContact O-CG1 3.28Å; V312-I316 PolarHBondContact O-N 3.12Å; A313-I316 PolarHBondContact O-N 3.47Å; I316-G320 PolarHBondContact O-N 3.08Å; I316-L367 HydrophobicContact CD1-CD2 4.32Å; I316-L367 HydrophobicContact CG1-CD2 3.8Å; I316-L367 HydrophobicContact CG1-CG 4.19Å; I316-V371 HydrophobicContact CG1-CG2 4.34Å
317	A	95.3	Very high	91.3	Very high	53 Å²	53	47.6 Å²	47.6	44%	0.438	26%	0.264	S	S	.	.	H	α-helix	trans	-65.9	-49.5	-178.7	0	0	0	0	0	111.9	A313 V314 G320 I321	A313-A317 WeakPolarHBondContact O-CB 3.35Å; A313-A317 PolarHBondContact O-N 2.88Å; V314-A317 PolarHBondContact O-N 3.44Å; A317-G320 PolarHBondContact O-N 2.79Å; A317-I321 WeakPolarHBondContact O-CB 3.26Å; A317-I321 WeakPolarHBondContact O-CD1 3.35Å; A317-I321 VanDerWaalsContact O-CG1 3.25Å; A317-I321 WeakPolarHBondContact O-CG1 3.33Å; A317-I321 PolarHBondContact O-N 3.34Å
318	A	95.3	Very high	91.5	Very high	35 Å²	35	53 Å²	53	29%	0.289	29%	0.285	S	S	.	.	H	α-helix	trans	-63.7	-46.8	178.4	0	0	0	0	0	111.6	V314 G320 I321 L322	V314-A318 VanDerWaalsContact O-CB 3.23Å; V314-A318 WeakPolarHBondContact O-CB 3.35Å; V314-A318 PolarHBondContact O-N 3.21Å; A318-G320 VanDerWaalsContact C-N 3.31Å; A318-G320 PolarHBondContact O-N 2.94Å; A318-I321 PolarHBondContact O-N 2.97Å; A318-L322 WeakPolarHBondContact O-CB 3.46Å; A318-L322 VanDerWaalsContact O-CG 3.29Å; A318-L322 WeakPolarHBondContact O-CG 3.11Å; A318-L322 PolarHBondContact O-N 3.44Å
319	G	95.6	Very high	91.7	Very high	0 Å²	0	58.3 Å²	58.3	0%	0	31%	0.309	C	S	.	.	H	α-helix	trans	-61.8	-39	176.2	0	0	0	0	0	112.2	G315 G323 C368 L372	G315-G319 PolarHBondContact O-N 3.46Å; G319-G323 WeakPolarHBondContact O-CA 3.31Å; G319-G323 PolarHBondContact O-N 3.37Å; G319-C368 WeakPolarHBondContact CA-O 3.46Å; G319-C368 PolarHBondContact N-SG 3.34Å; G319-C368 VanDerWaalsContact N-SG 3.43Å; G319-L372 VanDerWaalsContact O-CA 3.3Å; G319-L372 WeakPolarHBondContact O-CA 3.48Å; G319-L372 PolarHBondContact O-N 3.41Å
320	G	95.8	Very high	91.6	Very high	15 Å²	15	54.3 Å²	54.3	16%	0.155	29%	0.285	C	S	.	.	H	α-helix	trans	-64.6	-48.9	175.6	0	0	0	0	0	112.9	I316 A317 A318 G323 I324	I316-G320 PolarHBondContact O-N 3.08Å; A317-G320 PolarHBondContact O-N 2.79Å; A318-G320 VanDerWaalsContact C-N 3.31Å; A318-G320 PolarHBondContact O-N 2.94Å; G320-G323 PolarHBondContact O-N 2.84Å; G320-I324 WeakPolarHBondContact O-CB 3.49Å; G320-I324 VanDerWaalsContact O-CG1 3.25Å; G320-I324 WeakPolarHBondContact O-CG1 3.43Å; G320-I324 PolarHBondContact O-N 3.44Å
321	I	96.4	Very high	91.3	Very high	120 Å²	120	52.1 Å²	52.1	62%	0.615	28%	0.276	S	S	*	.	H	α-helix	trans	-61.2	-51	178.5	-69.4	163.3	0	0	0	110.6	A317 A318 G323 I324 F325	A317-I321 WeakPolarHBondContact O-CB 3.26Å; A317-I321 WeakPolarHBondContact O-CD1 3.35Å; A317-I321 VanDerWaalsContact O-CG1 3.25Å; A317-I321 WeakPolarHBondContact O-CG1 3.33Å; A317-I321 PolarHBondContact O-N 3.34Å; A318-I321 PolarHBondContact O-N 2.97Å; I321-G323 VanDerWaalsContact C-N 3.31Å; I321-G323 PolarHBondContact O-N 3.43Å; I321-I324 PolarHBondContact O-N 3.22Å; I321-F325 PolarHBondContact O-N 3.44Å
322	L	96.1	Very high	90.7	Very high	50 Å²	50	57.7 Å²	57.7	26%	0.262	30%	0.302	S	S	.	.	H	α-helix	trans	-66.4	-34.3	179.3	-64.6	173.5	0	0	0	111.6	A318 F325 L326 L348 L372	A318-L322 WeakPolarHBondContact O-CB 3.46Å; A318-L322 VanDerWaalsContact O-CG 3.29Å; A318-L322 WeakPolarHBondContact O-CG 3.11Å; A318-L322 PolarHBondContact O-N 3.44Å; L322-F325 WeakPolarHBondContact O-CB 3.4Å; L322-F325 PolarHBondContact O-N 2.71Å; L322-L326 WeakPolarHBondContact O-CG 3.2Å; L322-L326 PolarHBondContact O-N 2.7Å; L322-L348 HydrophobicContact CD2-CD1 4.41Å; L322-L372 HydrophobicContact CB-CD1 3.28Å; L322-L372 HydrophobicContact CD1-CD1 4.5Å
323	G	95.1	Very high	90	Very high	0 Å²	0	63.2 Å²	63.2	0%	0	33%	0.331	C	S	.	.	H	α-helix	trans	-69.1	-37.7	177.1	0	0	0	0	0	112.5	G319 G320 I321 L326 R327	G319-G323 WeakPolarHBondContact O-CA 3.31Å; G319-G323 PolarHBondContact O-N 3.37Å; G320-G323 PolarHBondContact O-N 2.84Å; I321-G323 VanDerWaalsContact C-N 3.31Å; I321-G323 PolarHBondContact O-N 3.43Å; G323-L326 PolarHBondContact O-N 2.83Å; G323-R327 WeakPolarHBondContact O-CB 3.38Å; G323-R327 PolarHBondContact O-N 2.86Å
324	I	94.4	Very high	89.4	Confident	92 Å²	92	64.3 Å²	64.3	47%	0.472	33%	0.327	S	S	.	.	H	α-helix	trans	-65.4	-40.6	170.6	-69	165.6	0	0	0	110.4	G320 I321 R327 Y328 V375	G320-I324 WeakPolarHBondContact O-CB 3.49Å; G320-I324 VanDerWaalsContact O-CG1 3.25Å; G320-I324 WeakPolarHBondContact O-CG1 3.43Å; G320-I324 PolarHBondContact O-N 3.44Å; I321-I324 PolarHBondContact O-N 3.22Å; I324-R327 WeakPolarHBondContact O-CB 3.29Å; I324-R327 PolarHBondContact O-N 3.36Å; I324-Y328 HydrophobicContact CG2-CD2 4.22Å; I324-Y328 HydrophobicContact CG2-CE2 3.91Å; I324-Y328 VanDerWaalsContact O-CD2 3.23Å; I324-Y328 WeakPolarHBondContact O-CD2 3.43Å; I324-Y328 PolarHBondContact O-N 3.28Å; I324-V375 HydrophobicContact CG1-CG1 3.9Å
325	F	93.8	Very high	88.5	Confident	92 Å²	92	67.2 Å²	67.2	40%	0.404	35%	0.345	S	S	.	.	H	α-helix	trans	-59	-48.9	173.6	171.4	-101.3	0	0	0	111.5	I321 L322 R327 Y328 F329	I321-F325 PolarHBondContact O-N 3.44Å; L322-F325 WeakPolarHBondContact O-CB 3.4Å; L322-F325 PolarHBondContact O-N 2.71Å; F325-R327 VanDerWaalsContact C-N 3.28Å; F325-R327 PolarHBondContact O-N 3Å; F325-Y328 PolarHBondContact O-N 3.18Å; F325-Y328 VanDerWaalsContact O-N 3.14Å; F325-F329 AromaticContact CD2-CD2 3.66Å; F325-F329 HydrophobicContact CD2-CD2 3.66Å; F325-F329 HydrophobicContact CD2-CE2 4.29Å; F325-F329 HydrophobicContact CD2-CG 4.4Å; F325-F329 HydrophobicContact CE1-CB 4.38Å; F325-F329 HydrophobicContact CE2-CB 4.1Å; F325-F329 AromaticContact CE2-CD2 3.49Å; F325-F329 HydrophobicContact CE2-CD2 3.49Å; F325-F329 VanDerWaalsContact CE2-CD2 3.49Å; F325-F329 HydrophobicContact CE2-CE2 4.12Å; F325-F329 AromaticContact CE2-CG 3.88Å; F325-F329 HydrophobicContact CE2-CG 3.88Å; F325-F329 HydrophobicContact CZ-CB 4Å; F325-F329 HydrophobicContact CZ-CD2 4.25Å; F325-F329 HydrophobicContact CZ-CG 4.21Å; F325-F329 PolarHBondContact O-N 3.25Å
326	L	92.2	Very high	88	Confident	1 Å²	1	70.5 Å²	70.5	1%	0.005	37%	0.368	C	S	.	.	H	α-helix	trans	-68.2	-23.1	177.9	-66.1	-166.4	0	0	0	114.6	L322 G323 Y328 F329 F344 V345 L348 L372 A376 W380	L322-L326 WeakPolarHBondContact O-CG 3.2Å; L322-L326 PolarHBondContact O-N 2.7Å; G323-L326 PolarHBondContact O-N 2.83Å; L326-Y328 VanDerWaalsContact C-N 3.28Å; L326-Y328 PolarHBondContact O-N 2.68Å; L326-F329 CarbonylContact C-O 3.36Å; L326-F329 WeakPolarHBondContact CA-O 3.41Å; L326-F329 VanDerWaalsContact O-O 3.04Å; L326-F344 HydrophobicContact CD1-CB 4.34Å; L326-F344 HydrophobicContact CD2-CB 3.57Å; L326-F344 HydrophobicContact CD2-CG 4.1Å; L326-V345 HydrophobicContact CD1-CB 4.27Å; L326-V345 HydrophobicContact CD1-CG2 3.6Å; L326-L348 HydrophobicContact CD1-CD1 4.1Å; L326-L348 HydrophobicContact CD2-CD1 3.85Å; L326-L348 HydrophobicContact CG-CD1 4.06Å; L326-L372 HydrophobicContact CD1-CD1 3.89Å; L326-L372 HydrophobicContact CD1-CG 4.29Å; L326-L372 HydrophobicContact CG-CD1 4.35Å; L326-A376 HydrophobicContact CB-CB 3.86Å; L326-W380 HydrophobicContact CB-CZ2 4.26Å; L326-W380 WeakPolarHBondContact O-CZ2 3.13Å; L326-W380 PolarHBondContact O-NE1 3.21Å
327	R	88.9	Confident	87.7	Confident	107 Å²	107	67.5 Å²	67.5	40%	0.404	35%	0.353	S	S	.	.	H	α-helix	trans	-62.9	-36.9	171.3	173.4	167.3	-175.8	169.3	1.9	111.8	G323 I324 F325	G323-R327 WeakPolarHBondContact O-CB 3.38Å; G323-R327 PolarHBondContact O-N 2.86Å; I324-R327 WeakPolarHBondContact O-CB 3.29Å; I324-R327 PolarHBondContact O-N 3.36Å; F325-R327 VanDerWaalsContact C-N 3.28Å; F325-R327 PolarHBondContact O-N 3Å
328	Y	85.9	Confident	87.3	Confident	152 Å²	152	66.1 Å²	66.1	60%	0.596	34%	0.341	S	S	*	.	H	α-helix	trans	-95.2	-30.7	180	-64.4	-66	0	0	0	113.7	I324 F325 L326 P330 S331	I324-Y328 HydrophobicContact CG2-CD2 4.22Å; I324-Y328 HydrophobicContact CG2-CE2 3.91Å; I324-Y328 VanDerWaalsContact O-CD2 3.23Å; I324-Y328 WeakPolarHBondContact O-CD2 3.43Å; I324-Y328 PolarHBondContact O-N 3.28Å; F325-Y328 PolarHBondContact O-N 3.18Å; F325-Y328 VanDerWaalsContact O-N 3.14Å; L326-Y328 VanDerWaalsContact C-N 3.28Å; L326-Y328 PolarHBondContact O-N 2.68Å; Y328-P330 CarbonylContact O-C 3.16Å; Y328-S331 PolarHBondContact O-N 3.45Å
329	F	86.7	Confident	87	Confident	112 Å²	112	72.8 Å²	72.8	49%	0.491	36%	0.359	S	S	.	.	S	Bend	trans	-114.6	126.4	-178.6	-67.9	-82.4	0	0	0	111.7	F325 L326	F325-F329 AromaticContact CD2-CD2 3.66Å; F325-F329 HydrophobicContact CD2-CD2 3.66Å; F325-F329 HydrophobicContact CD2-CE2 4.29Å; F325-F329 HydrophobicContact CD2-CG 4.4Å; F325-F329 HydrophobicContact CE1-CB 4.38Å; F325-F329 HydrophobicContact CE2-CB 4.1Å; F325-F329 AromaticContact CE2-CD2 3.49Å; F325-F329 HydrophobicContact CE2-CD2 3.49Å; F325-F329 VanDerWaalsContact CE2-CD2 3.49Å; F325-F329 HydrophobicContact CE2-CE2 4.12Å; F325-F329 AromaticContact CE2-CG 3.88Å; F325-F329 HydrophobicContact CE2-CG 3.88Å; F325-F329 HydrophobicContact CZ-CB 4Å; F325-F329 HydrophobicContact CZ-CD2 4.25Å; F325-F329 HydrophobicContact CZ-CG 4.21Å; F325-F329 PolarHBondContact O-N 3.25Å; L326-F329 CarbonylContact C-O 3.36Å; L326-F329 WeakPolarHBondContact CA-O 3.41Å; L326-F329 VanDerWaalsContact O-O 3.04Å
330	P	82.1	Confident	86.8	Confident	3 Å²	3	75.7 Å²	75.7	2%	0.019	37%	0.372	C	S	.	.	S	Bend	cis	-74.8	151.4	1.9	-3	20.5	0	0	0	112.4	Y328 Q334 L337 K340 R341 F344	Y328-P330 CarbonylContact O-C 3.16Å; P330-Q334 HydrophobicContact CB-CG 4.46Å; P330-L337 HydrophobicContact CB-CD1 3.82Å; P330-L337 HydrophobicContact CG-CD1 4.04Å; P330-L337 WeakPolarHBondContact O-CD1 3.44Å; P330-K340 HydrophobicContact CB-CB 4.49Å; P330-K340 HydrophobicContact CB-CD 4.46Å; P330-K340 HydrophobicContact CG-CB 3.49Å; P330-K340 VanDerWaalsContact CG-CB 3.49Å; P330-K340 HydrophobicContact CG-CD 4.28Å; P330-R341 VanDerWaalsContact CD-CG 3.46Å; P330-R341 HydrophobicContact CG-CG 4.23Å; P330-R341 PolarHBondContact O-NH2 3.39Å; P330-F344 HydrophobicContact CG-CD2 4.28Å; P330-F344 HydrophobicContact CG-CE2 4.36Å
331	S	80.8	Confident	86.6	Confident	39 Å²	39	75 Å²	75	27%	0.273	37%	0.365	S	S	.	.			trans	-66.9	157.9	175.5	71.9	0	0	0	0	111.5	Y328 D333 Q334 L337	Y328-S331 PolarHBondContact O-N 3.45Å; S331-D333 WeakPolarHBondContact CB-OD2 3.46Å; S331-D333 PolarHBondContact O-N 3.45Å; S331-D333 PolarHBondContact OG-OD2 2.85Å; S331-Q334 PolarHBondContact O-N 3.32Å; S331-L337 WeakPolarHBondContact O-CD1 3.36Å
332	H	75.3	Confident	86.4	Confident	119 Å²	119	69.4 Å²	69.4	55%	0.551	34%	0.336	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.3	-20.2	-175	-75.6	-97.1	0	0	0	113.7	Q334 R341 E383	H332-Q334 PolarHBondContact O-N 2.74Å; H332-R341 PolarHBondContact CE1-NH2 3.18Å; H332-R341 PolarHBondContact NE2-NH2 2.93Å; H332-E383 IonicContact CE1-OE1 2.94Å; H332-E383 PolarHBondContact CE1-OE1 3.31Å; H332-E383 IonicContact ND1-OE1 3.74Å; H332-E383 PolarHBondContact ND1-OE1 2.92Å
333	D	73.2	Confident	86.3	Confident	143 Å²	143	75.1 Å²	75.1	77%	0.765	36%	0.355	S	S	*	.	T	Hydrogen-bonded Turn	trans	-73.5	-8.2	-178.7	-24.8	-77.9	0	0	0	112.7	S331	S331-D333 WeakPolarHBondContact CB-OD2 3.46Å; S331-D333 PolarHBondContact O-N 3.45Å; S331-D333 PolarHBondContact OG-OD2 2.85Å
334	Q	78.6	Confident	86.3	Confident	76 Å²	76	78.9 Å²	78.9	36%	0.355	37%	0.372	S	S	.	.	S	Bend	trans	-89.3	129.1	-174.9	-64	-163.5	29.1	0	0	113.3	P330 S331 H332	P330-Q334 HydrophobicContact CB-CG 4.46Å; S331-Q334 PolarHBondContact O-N 3.32Å; H332-Q334 PolarHBondContact O-N 2.74Å
335	T	73.5	Confident	86.4	Confident	117 Å²	117	74.5 Å²	74.5	72%	0.718	35%	0.349	S	S	*	.	T	Hydrogen-bonded Turn	trans	-57.9	151.3	166.4	58.4	0	0	0	0	111.5	L337 K340	T335-L337 VanDerWaalsContact C-N 3.28Å; T335-L337 PolarHBondContact O-N 3.09Å; T335-K340 WeakPolarHBondContact O-CE 3.32Å; T335-K340 PolarHBondContact O-NZ 3.11Å
336	S	80.9	Confident	86.4	Confident	69 Å²	69	71.2 Å²	71.2	48%	0.483	34%	0.336	S	S	.	.	T	Hydrogen-bonded Turn	trans	55.2	32.2	-177.5	68.4	0	0	0	0	115.9	A338 W339 K340	S336-A338 VanDerWaalsContact C-N 3.32Å; S336-A338 PolarHBondContact O-N 2.87Å; S336-A338 VanDerWaalsContact O-N 3.13Å; S336-W339 PolarHBondContact O-N 3.32Å; S336-K340 PolarHBondContact O-N 3.44Å; S336-K340 VanDerWaalsContact O-N 3.16Å
337	L	85.1	Confident	86.6	Confident	23 Å²	23	72.6 Å²	72.6	12%	0.12	35%	0.35	C	S	.	.	H	α-helix	trans	-44.9	-46.3	-177	-171.2	57.4	0	0	0	114.9	P330 S331 T335 K340 R341 E383	P330-L337 HydrophobicContact CB-CD1 3.82Å; P330-L337 HydrophobicContact CG-CD1 4.04Å; P330-L337 WeakPolarHBondContact O-CD1 3.44Å; S331-L337 WeakPolarHBondContact O-CD1 3.36Å; T335-L337 VanDerWaalsContact C-N 3.28Å; T335-L337 PolarHBondContact O-N 3.09Å; L337-K340 PolarHBondContact O-N 3.48Å; L337-R341 HydrophobicContact CD1-CG 4.3Å; L337-R341 WeakPolarHBondContact O-CB 3.49Å; L337-R341 WeakPolarHBondContact O-CG 3.31Å; L337-R341 PolarHBondContact O-N 2.81Å; L337-E383 HydrophobicContact CD2-CG 4.33Å
338	A	87.8	Confident	87	Confident	23 Å²	23	69.2 Å²	69.2	19%	0.19	34%	0.34	C	S	.	.	H	α-helix	trans	-61.7	-44.4	179	0	0	0	0	0	112.9	S336 R341 S342 A386 I390	S336-A338 VanDerWaalsContact C-N 3.32Å; S336-A338 PolarHBondContact O-N 2.87Å; S336-A338 VanDerWaalsContact O-N 3.13Å; A338-R341 PolarHBondContact O-N 3.38Å; A338-S342 WeakPolarHBondContact O-CB 3.35Å; A338-S342 PolarHBondContact O-N 3.46Å; A338-S342 PolarHBondContact O-OG 2.69Å; A338-S342 VanDerWaalsContact O-OG 3.11Å; A338-A386 HydrophobicContact CB-CB 3.69Å; A338-I390 HydrophobicContact CB-CD1 4.3Å
339	W	89.3	Confident	87.4	Confident	176 Å²	176	62 Å²	62	67%	0.667	31%	0.312	S	S	*	.	H	α-helix	trans	-64.8	-42.2	177.6	-82.3	105.2	0	0	0	112.2	S336 S342 Y343 I390	S336-W339 PolarHBondContact O-N 3.32Å; W339-S342 PolarHBondContact O-N 3.06Å; W339-Y343 WeakPolarHBondContact O-CB 3.26Å; W339-Y343 PolarHBondContact O-N 2.88Å; W339-I390 HydrophobicContact CD2-CD1 3.89Å; W339-I390 HydrophobicContact CE3-CD1 4.15Å; W339-I390 HydrophobicContact CE3-CG2 4.14Å; W339-I390 HydrophobicContact CG-CD1 4.14Å; W339-I390 HydrophobicContact CH2-CG2 4.43Å; W339-I390 HydrophobicContact CZ3-CG2 3.88Å
340	K	91.1	Very high	87.8	Confident	61 Å²	61	59.5 Å²	59.5	27%	0.265	30%	0.302	S	S	.	.	H	α-helix	trans	-64.9	-45.4	176.4	-68.5	173.8	176.1	169.2	0	111.7	P330 T335 S336 L337 Y343 F344	P330-K340 HydrophobicContact CB-CB 4.49Å; P330-K340 HydrophobicContact CB-CD 4.46Å; P330-K340 HydrophobicContact CG-CB 3.49Å; P330-K340 VanDerWaalsContact CG-CB 3.49Å; P330-K340 HydrophobicContact CG-CD 4.28Å; T335-K340 WeakPolarHBondContact O-CE 3.32Å; T335-K340 PolarHBondContact O-NZ 3.11Å; S336-K340 PolarHBondContact O-N 3.44Å; S336-K340 VanDerWaalsContact O-N 3.16Å; L337-K340 PolarHBondContact O-N 3.48Å; K340-Y343 PolarHBondContact O-N 3.37Å; K340-F344 VanDerWaalsContact O-CD2 3.26Å; K340-F344 WeakPolarHBondContact O-CD2 3.3Å; K340-F344 PolarHBondContact O-N 3.32Å
341	R	92.1	Very high	88.4	Confident	1 Å²	1	65.7 Å²	65.7	0%	0.004	33%	0.329	C	S	.	.	H	α-helix	trans	-59.5	-47.4	174	-75.1	178.1	174.9	168.5	4.7	111	P330 H332 L337 A338 Y343 F344 V345 W380 E383 V387	P330-R341 VanDerWaalsContact CD-CG 3.46Å; P330-R341 HydrophobicContact CG-CG 4.23Å; P330-R341 PolarHBondContact O-NH2 3.39Å; H332-R341 PolarHBondContact CE1-NH2 3.18Å; H332-R341 PolarHBondContact NE2-NH2 2.93Å; L337-R341 HydrophobicContact CD1-CG 4.3Å; L337-R341 WeakPolarHBondContact O-CB 3.49Å; L337-R341 WeakPolarHBondContact O-CG 3.31Å; L337-R341 PolarHBondContact O-N 2.81Å; A338-R341 PolarHBondContact O-N 3.38Å; R341-Y343 PolarHBondContact O-N 3.47Å; R341-F344 PolarHBondContact O-N 2.89Å; R341-V345 VanDerWaalsContact O-CG2 3.28Å; R341-V345 WeakPolarHBondContact O-CG2 3.35Å; R341-V345 PolarHBondContact O-N 3Å; R341-W380 HydrophobicContact CB-CH2 4.01Å; R341-W380 HydrophobicContact CB-CZ2 4.06Å; R341-W380 HydrophobicContact CG-CH2 4.31Å; R341-W380 HydrophobicContact CG-CZ2 3.84Å; R341-W380 VanDerWaalsContact CZ-CD1 3.45Å; R341-E383 IonicContact CZ-OE1 2.71Å; R341-E383 IonicContact NH1-OE1 3.89Å; R341-E383 PolarHBondContact NH1-OE1 3.17Å; R341-E383 IonicContact NH1-OE2 3.1Å; R341-V387 HydrophobicContact CB-CG2 3.72Å
342	S	92.5	Very high	89	Confident	1 Å²	1	64.4 Å²	64.4	1%	0.007	32%	0.321	C	S	.	.	H	α-helix	trans	-59.6	-43.3	175.1	-68.6	0	0	0	0	113.5	A338 W339 L346 V387 I390	A338-S342 WeakPolarHBondContact O-CB 3.35Å; A338-S342 PolarHBondContact O-N 3.46Å; A338-S342 PolarHBondContact O-OG 2.69Å; A338-S342 VanDerWaalsContact O-OG 3.11Å; W339-S342 PolarHBondContact O-N 3.06Å; S342-L346 WeakPolarHBondContact O-CB 3.07Å; S342-L346 VanDerWaalsContact O-CG 3.32Å; S342-L346 WeakPolarHBondContact O-CG 3.49Å; S342-L346 PolarHBondContact O-N 3.07Å; S342-V387 WeakPolarHBondContact OG-CA 3.24Å; S342-I390 WeakPolarHBondContact OG-CB 3.4Å; S342-I390 WeakPolarHBondContact OG-CD1 3.18Å
343	Y	93.8	Very high	89.8	Confident	171 Å²	171	59 Å²	59	67%	0.671	30%	0.296	S	S	*	.	H	α-helix	trans	-59.6	-49.5	176.1	172.8	-95.3	0	0	0	111.3	W339 K340 R341 G347	W339-Y343 WeakPolarHBondContact O-CB 3.26Å; W339-Y343 PolarHBondContact O-N 2.88Å; K340-Y343 PolarHBondContact O-N 3.37Å; R341-Y343 PolarHBondContact O-N 3.47Å; Y343-G347 PolarHBondContact O-N 3.36Å
344	F	94.8	Very high	90.6	Very high	79 Å²	79	55.9 Å²	55.9	35%	0.346	28%	0.276	S	S	.	.	H	α-helix	trans	-65.7	-43	179.8	-83.3	-62.5	0	0	0	113.2	L326 P330 K340 R341 L348	L326-F344 HydrophobicContact CD1-CB 4.34Å; L326-F344 HydrophobicContact CD2-CB 3.57Å; L326-F344 HydrophobicContact CD2-CG 4.1Å; P330-F344 HydrophobicContact CG-CD2 4.28Å; P330-F344 HydrophobicContact CG-CE2 4.36Å; K340-F344 VanDerWaalsContact O-CD2 3.26Å; K340-F344 WeakPolarHBondContact O-CD2 3.3Å; K340-F344 PolarHBondContact O-N 3.32Å; R341-F344 PolarHBondContact O-N 2.89Å; F344-L348 VanDerWaalsContact O-CB 3.28Å; F344-L348 WeakPolarHBondContact O-CB 3.34Å; F344-L348 WeakPolarHBondContact O-CG 3.45Å; F344-L348 PolarHBondContact O-N 3.39Å
345	V	95.5	Very high	91.2	Very high	0 Å²	0	52.8 Å²	52.8	0%	0	26%	0.264	C	S	.	.	H	α-helix	trans	-60.7	-55.6	176.1	177.9	0	0	0	0	109.8	T188 L326 R341 G347 L348 S349 A373 W380	T188-V345 HydrophobicContact CG2-CG1 3.33Å; L326-V345 HydrophobicContact CD1-CB 4.27Å; L326-V345 HydrophobicContact CD1-CG2 3.6Å; R341-V345 VanDerWaalsContact O-CG2 3.28Å; R341-V345 WeakPolarHBondContact O-CG2 3.35Å; R341-V345 PolarHBondContact O-N 3Å; V345-G347 VanDerWaalsContact C-N 3.33Å; V345-G347 PolarHBondContact O-N 3.03Å; V345-L348 PolarHBondContact O-N 3.2Å; V345-S349 VanDerWaalsContact O-CB 3.23Å; V345-S349 WeakPolarHBondContact O-CB 3.1Å; V345-S349 PolarHBondContact O-N 3.47Å; V345-S349 PolarHBondContact O-OG 3.4Å; V345-A373 HydrophobicContact CG1-CB 4.4Å; V345-W380 HydrophobicContact CG2-CH2 3.5Å; V345-W380 VanDerWaalsContact CG2-CH2 3.5Å; V345-W380 HydrophobicContact CG2-CZ3 4.08Å
346	L	95.4	Very high	92	Very high	23 Å²	23	47.7 Å²	47.7	12%	0.12	23%	0.233	C	C	.	.	H	α-helix	trans	-62.1	-41	-177.6	-69.8	174.1	0	0	0	112	I185 T188 S342 M350 V391 A394	I185-L346 HydrophobicContact CG1-CD2 4.06Å; T188-L346 HydrophobicContact CG2-CD2 4.15Å; S342-L346 WeakPolarHBondContact O-CB 3.07Å; S342-L346 VanDerWaalsContact O-CG 3.32Å; S342-L346 WeakPolarHBondContact O-CG 3.49Å; S342-L346 PolarHBondContact O-N 3.07Å; L346-M350 HydrophobicContact CB-CE 4.35Å; L346-M350 WeakPolarHBondContact O-CB 3.29Å; L346-M350 VanDerWaalsContact O-CE 3.26Å; L346-M350 WeakPolarHBondContact O-CE 3.44Å; L346-M350 WeakPolarHBondContact O-CG 3.37Å; L346-M350 PolarHBondContact O-N 2.89Å; L346-V391 HydrophobicContact CD1-CG2 4.35Å; L346-V391 HydrophobicContact CD2-CG1 4.4Å; L346-V391 HydrophobicContact CD2-CG2 4.07Å; L346-V391 HydrophobicContact CG-CG2 4.19Å; L346-A394 HydrophobicContact CD1-CB 4.11Å
347	G	95.8	Very high	92.1	Very high	30 Å²	30	47.2 Å²	47.2	31%	0.309	23%	0.225	S	C	.	.	H	α-helix	trans	-63.2	-50	177.4	0	0	0	0	0	112.9	Y343 V345 M350 F351	Y343-G347 PolarHBondContact O-N 3.36Å; V345-G347 VanDerWaalsContact C-N 3.33Å; V345-G347 PolarHBondContact O-N 3.03Å; G347-M350 PolarHBondContact O-N 3.43Å; G347-F351 WeakPolarHBondContact O-CB 3.43Å; G347-F351 PolarHBondContact O-N 2.68Å
348	L	96.3	Very high	92.2	Very high	36 Å²	36	55.4 Å²	55.4	19%	0.188	26%	0.255	C	S	.	.	H	α-helix	trans	-69.6	-35.1	178.4	-70	179.2	0	0	0	112.4	L322 L326 F344 V345 F351 A352 L372	L322-L348 HydrophobicContact CD2-CD1 4.41Å; L326-L348 HydrophobicContact CD1-CD1 4.1Å; L326-L348 HydrophobicContact CD2-CD1 3.85Å; L326-L348 HydrophobicContact CG-CD1 4.06Å; F344-L348 VanDerWaalsContact O-CB 3.28Å; F344-L348 WeakPolarHBondContact O-CB 3.34Å; F344-L348 WeakPolarHBondContact O-CG 3.45Å; F344-L348 PolarHBondContact O-N 3.39Å; V345-L348 PolarHBondContact O-N 3.2Å; L348-F351 PolarHBondContact O-N 3.27Å; L348-A352 VanDerWaalsContact O-CB 3.27Å; L348-A352 WeakPolarHBondContact O-CB 3.43Å; L348-A352 PolarHBondContact O-N 3.39Å; L348-L372 HydrophobicContact CB-CD1 4.42Å; L348-L372 HydrophobicContact CB-CD2 3.95Å; L348-L372 HydrophobicContact CD1-CD1 4.41Å
349	S	95	Very high	92.1	Very high	0 Å²	0	60.9 Å²	60.9	0%	0	28%	0.275	C	S	.	.	H	α-helix	trans	-61.2	-44	171.2	-66.6	0	0	0	0	111.9	S184 T188 V345 A352 V353 T369 L372	S184-S349 WeakPolarHBondContact OG-CB 3.42Å; S184-S349 PolarHBondContact OG-O 3.37Å; T188-S349 VanDerWaalsContact OG1-CB 3.23Å; T188-S349 WeakPolarHBondContact OG1-CB 3.34Å; T188-S349 PolarHBondContact OG1-OG 2.92Å; V345-S349 VanDerWaalsContact O-CB 3.23Å; V345-S349 WeakPolarHBondContact O-CB 3.1Å; V345-S349 PolarHBondContact O-N 3.47Å; V345-S349 PolarHBondContact O-OG 3.4Å; S349-A352 PolarHBondContact O-N 3.14Å; S349-V353 PolarHBondContact O-N 3.49Å; S349-T369 PolarHBondContact O-OG1 2.9Å; S349-L372 WeakPolarHBondContact OG-CD2 3.39Å
350	M	94.8	Very high	91.8	Very high	59 Å²	59	54 Å²	54	29%	0.291	26%	0.258	S	S	.	.	H	α-helix	trans	-67.7	-44.6	178	-75.9	-176.8	-73.1	0	0	110.4	I181 S184 L346 G347 A352 V353 F354	I181-M350 HydrophobicContact CG1-SD 4.29Å; I181-M350 HydrophobicContact CG2-SD 3.85Å; S184-M350 WeakPolarHBondContact OG-CA 3.49Å; S184-M350 PolarHBondContact OG-N 3.05Å; L346-M350 HydrophobicContact CB-CE 4.35Å; L346-M350 WeakPolarHBondContact O-CB 3.29Å; L346-M350 VanDerWaalsContact O-CE 3.26Å; L346-M350 WeakPolarHBondContact O-CE 3.44Å; L346-M350 WeakPolarHBondContact O-CG 3.37Å; L346-M350 PolarHBondContact O-N 2.89Å; G347-M350 PolarHBondContact O-N 3.43Å; M350-A352 VanDerWaalsContact C-N 3.28Å; M350-A352 PolarHBondContact O-N 3.08Å; M350-V353 PolarHBondContact O-N 3.38Å; M350-F354 VanDerWaalsContact O-CD2 3.29Å; M350-F354 WeakPolarHBondContact O-CD2 3.39Å; M350-F354 PolarHBondContact O-N 3.17Å
351	F	95.2	Very high	91.5	Very high	134 Å²	134	54.1 Å²	54.1	59%	0.588	26%	0.259	S	S	*	.	H	α-helix	trans	-58.5	-38.6	174.2	-179.5	-101.7	0	0	0	112.4	G347 L348 G355	G347-F351 WeakPolarHBondContact O-CB 3.43Å; G347-F351 PolarHBondContact O-N 2.68Å; L348-F351 PolarHBondContact O-N 3.27Å; F351-G355 VanDerWaalsContact O-CA 3.25Å; F351-G355 WeakPolarHBondContact O-CA 3.46Å; F351-G355 PolarHBondContact O-N 2.87Å
352	A	93.9	Very high	91	Very high	12 Å²	12	54.6 Å²	54.6	10%	0.099	26%	0.262	C	S	.	.	H	α-helix	trans	-63.7	-44.4	176.5	0	0	0	0	0	112.4	L348 S349 M350 S356 G365 C368	L348-A352 VanDerWaalsContact O-CB 3.27Å; L348-A352 WeakPolarHBondContact O-CB 3.43Å; L348-A352 PolarHBondContact O-N 3.39Å; S349-A352 PolarHBondContact O-N 3.14Å; M350-A352 VanDerWaalsContact C-N 3.28Å; M350-A352 PolarHBondContact O-N 3.08Å; A352-S356 WeakPolarHBondContact O-CB 3.22Å; A352-S356 PolarHBondContact O-N 3.39Å; A352-S356 PolarHBondContact O-OG 3.47Å; A352-G365 WeakPolarHBondContact O-CA 3.49Å; A352-C368 HydrophobicContact CB-CB 4.11Å
353	V	90.4	Very high	90.5	Very high	4 Å²	4	54.6 Å²	54.6	2%	0.024	26%	0.262	C	S	.	.	H	α-helix	trans	-68.3	-48.4	178.9	172.9	0	0	0	0	112.1	N180 L183 S349 M350 S356 I357	N180-V353 HydrophobicContact CB-CG1 4Å; L183-V353 HydrophobicContact CD2-CG1 4.12Å; S349-V353 PolarHBondContact O-N 3.49Å; M350-V353 PolarHBondContact O-N 3.38Å; V353-S356 PolarHBondContact O-OG 3.3Å; V353-S356 VanDerWaalsContact O-OG 3.09Å; V353-I357 WeakPolarHBondContact O-CG1 3.34Å
354	F	91	Very high	90.2	Very high	79 Å²	79	46.9 Å²	46.9	35%	0.346	23%	0.234	S	C	.	.	H	α-helix	trans	-72.4	-38.6	179.6	-73.7	-71.7	0	0	0	112.3	A177 N180 I181 M350 I357 Y358	A177-F354 HydrophobicContact CB-CE1 4.39Å; A177-F354 HydrophobicContact CB-CZ 4.39Å; N180-F354 HydrophobicContact CB-CE1 3.99Å; N180-F354 HydrophobicContact CB-CE2 4.49Å; N180-F354 HydrophobicContact CB-CZ 3.82Å; I181-F354 HydrophobicContact CG1-CE2 3.78Å; I181-F354 HydrophobicContact CG1-CZ 3.94Å; M350-F354 VanDerWaalsContact O-CD2 3.29Å; M350-F354 WeakPolarHBondContact O-CD2 3.39Å; M350-F354 PolarHBondContact O-N 3.17Å; F354-I357 PolarHBondContact O-N 3.36Å; F354-Y358 PolarHBondContact O-N 3.2Å; F354-Y358 VanDerWaalsContact O-N 3.13Å
355	G	91.4	Very high	90	Very high	10 Å²	10	43.2 Å²	43.2	10%	0.103	22%	0.218	C	C	.	.	H	α-helix	trans	-64.8	-39.9	176.8	0	0	0	0	0	112.5	F351 I357 Y358 F359	F351-G355 VanDerWaalsContact O-CA 3.25Å; F351-G355 WeakPolarHBondContact O-CA 3.46Å; F351-G355 PolarHBondContact O-N 2.87Å; G355-I357 VanDerWaalsContact C-N 3.3Å; G355-I357 PolarHBondContact O-N 3.46Å; G355-Y358 PolarHBondContact O-N 2.93Å; G355-Y358 VanDerWaalsContact O-N 3.15Å; G355-F359 WeakPolarHBondContact O-CD2 3.06Å; G355-F359 PolarHBondContact O-N 3.16Å
356	S	89.3	Confident	89.6	Confident	10 Å²	10	43.4 Å²	43.4	7%	0.07	22%	0.22	C	C	.	.	H	α-helix	trans	-65	-34.5	178.8	72.7	0	0	0	0	113	A352 V353 G360 F361 S364 G365	A352-S356 WeakPolarHBondContact O-CB 3.22Å; A352-S356 PolarHBondContact O-N 3.39Å; A352-S356 PolarHBondContact O-OG 3.47Å; V353-S356 PolarHBondContact O-OG 3.3Å; V353-S356 VanDerWaalsContact O-OG 3.09Å; S356-G360 PolarHBondContact O-N 3.41Å; S356-F361 WeakPolarHBondContact CB-O 3.5Å; S356-F361 CarbonylContact O-C 3.51Å; S356-F361 VanDerWaalsContact O-C 3.27Å; S356-F361 PolarHBondContact O-N 2.92Å; S356-S364 WeakPolarHBondContact CB-OG 3.35Å; S356-G365 VanDerWaalsContact CB-CA 3.48Å; S356-G365 VanDerWaalsContact CB-N 3.33Å; S356-G365 VanDerWaalsContact OG-CA 3.24Å; S356-G365 WeakPolarHBondContact OG-CA 3.44Å; S356-G365 PolarHBondContact OG-N 3.34Å
357	I	84	Confident	89.3	Confident	60 Å²	60	42.5 Å²	42.5	31%	0.308	22%	0.215	S	C	.	.	H	α-helix	trans	-66	-46.3	172.1	-62.8	167.5	0	0	0	109.7	V353 F354 G355 G360	V353-I357 WeakPolarHBondContact O-CG1 3.34Å; F354-I357 PolarHBondContact O-N 3.36Å; G355-I357 VanDerWaalsContact C-N 3.3Å; G355-I357 PolarHBondContact O-N 3.46Å; I357-G360 PolarHBondContact O-N 2.95Å
358	Y	86.9	Confident	89.2	Confident	194 Å²	194	41.5 Å²	41.5	76%	0.761	20%	0.203	S	C	*	.	H	α-helix	trans	-63.2	-41.9	179.2	-179.1	-98.5	0	0	0	113.6	F354 G355 G360	F354-Y358 PolarHBondContact O-N 3.2Å; F354-Y358 VanDerWaalsContact O-N 3.13Å; G355-Y358 PolarHBondContact O-N 2.93Å; G355-Y358 VanDerWaalsContact O-N 3.15Å; Y358-G360 PolarHBondContact O-N 3.19Å
359	F	86.7	Confident	89.1	Confident	138 Å²	138	39.8 Å²	39.8	61%	0.605	19%	0.194	S	C	*	.	T	Hydrogen-bonded Turn	trans	-78.3	2.5	177.3	-67.1	-59.8	0	0	0	113.9	G355 F361	G355-F359 WeakPolarHBondContact O-CD2 3.06Å; G355-F359 PolarHBondContact O-N 3.16Å; F359-F361 HydrophobicContact CB-CD2 4.43Å; F359-F361 WeakPolarHBondContact O-CD2 3.49Å
360	G	82.7	Confident	88.8	Confident	31 Å²	31	40.1 Å²	40.1	32%	0.32	20%	0.196	S	C	.	.	T	Hydrogen-bonded Turn	trans	72.6	29.3	176.6	0	0	0	0	0	114.7	R307 S356 I357 Y358	R307-G360 PolarHBondContact NH2-O 2.84Å; S356-G360 PolarHBondContact O-N 3.41Å; I357-G360 PolarHBondContact O-N 2.95Å; Y358-G360 PolarHBondContact O-N 3.19Å
361	F	84.8	Confident	88.7	Confident	65 Å²	65	38.4 Å²	38.4	29%	0.285	19%	0.189	S	C	.	.			trans	-130.5	60	176.1	-67.4	-66.8	0	0	0	110.8	E311 S356 F359 G363 S364	E311-F361 HydrophobicContact CG-CB 3.99Å; E311-F361 HydrophobicContact CG-CD1 3.55Å; E311-F361 HydrophobicContact CG-CE1 4.49Å; E311-F361 HydrophobicContact CG-CG 4.22Å; S356-F361 WeakPolarHBondContact CB-O 3.5Å; S356-F361 CarbonylContact O-C 3.51Å; S356-F361 VanDerWaalsContact O-C 3.27Å; S356-F361 PolarHBondContact O-N 2.92Å; F359-F361 HydrophobicContact CB-CD2 4.43Å; F359-F361 WeakPolarHBondContact O-CD2 3.49Å; F361-G363 VanDerWaalsContact C-N 3.26Å; F361-G363 PolarHBondContact O-N 3.39Å; F361-G363 VanDerWaalsContact O-N 3.13Å; F361-S364 WeakPolarHBondContact O-CB 3.29Å; F361-S364 PolarHBondContact O-N 2.87Å; F361-S364 PolarHBondContact O-OG 2.86Å
362	P	81.9	Confident	88.7	Confident	10 Å²	10	32 Å²	32	7%	0.065	16%	0.161	C	C	.	.	H	α-helix	trans	-58.6	-31.3	-165.7	23.5	-34.2	0	0	0	114.1	L292 S364 T476	L292-P362 HydrophobicContact CD2-CB 4.33Å; P362-S364 VanDerWaalsContact C-N 3.3Å; P362-S364 PolarHBondContact O-N 3.34Å; P362-T476 HydrophobicContact CB-CG2 4.31Å; P362-T476 HydrophobicContact CG-CG2 4.13Å
363	G	80.3	Confident	88.7	Confident	1 Å²	1	31.4 Å²	31.4	1%	0.01	16%	0.156	C	C	.	.	H	α-helix	trans	-69.6	-23.8	176.7	0	0	0	0	0	114	N289 E311 F361	N289-G363 VanDerWaalsContact CB-O 3.26Å; N289-G363 WeakPolarHBondContact CB-O 3.33Å; N289-G363 PolarHBondContact ND2-O 3.3Å; E311-G363 WeakPolarHBondContact OE2-CA 3.26Å; E311-G363 PolarHBondContact OE2-N 3.5Å; F361-G363 VanDerWaalsContact C-N 3.26Å; F361-G363 PolarHBondContact O-N 3.39Å; F361-G363 VanDerWaalsContact O-N 3.13Å
364	S	88.5	Confident	88.7	Confident	10 Å²	10	33.7 Å²	33.7	7%	0.07	17%	0.166	C	C	.	.	H	α-helix	trans	-71.9	-31.8	-175	68.9	0	0	0	0	114	E311 S356 F361 P362 L367 C368	E311-S364 WeakPolarHBondContact O-CB 3.44Å; S356-S364 WeakPolarHBondContact CB-OG 3.35Å; F361-S364 WeakPolarHBondContact O-CB 3.29Å; F361-S364 PolarHBondContact O-N 2.87Å; F361-S364 PolarHBondContact O-OG 2.86Å; P362-S364 VanDerWaalsContact C-N 3.3Å; P362-S364 PolarHBondContact O-N 3.34Å; S364-L367 PolarHBondContact O-N 3.34Å; S364-C368 WeakPolarHBondContact O-CB 3.4Å; S364-C368 PolarHBondContact O-N 3.43Å
365	G	89.2	Confident	88.8	Confident	1 Å²	1	31.6 Å²	31.6	1%	0.01	16%	0.159	C	C	.	.	H	α-helix	trans	-71.4	-38.5	-170.4	0	0	0	0	0	114.6	A352 S356 T369	A352-G365 WeakPolarHBondContact O-CA 3.49Å; S356-G365 VanDerWaalsContact CB-CA 3.48Å; S356-G365 VanDerWaalsContact CB-N 3.33Å; S356-G365 VanDerWaalsContact OG-CA 3.24Å; S356-G365 WeakPolarHBondContact OG-CA 3.44Å; S356-G365 PolarHBondContact OG-N 3.34Å; G365-T369 WeakPolarHBondContact O-CB 3.18Å; G365-T369 PolarHBondContact O-N 3.35Å; G365-T369 PolarHBondContact O-OG1 3.38Å
366	G	87.7	Confident	88.9	Confident	4 Å²	4	31.1 Å²	31.1	4%	0.041	15%	0.154	C	C	.	.	H	α-helix	trans	-66.5	-41.7	174.4	0	0	0	0	0	112.2	T369 L370	G366-T369 WeakPolarHBondContact O-CB 3.26Å; G366-T369 PolarHBondContact O-N 3.03Å; G366-L370 PolarHBondContact O-N 2.91Å; G366-L370 VanDerWaalsContact O-N 3.15Å
367	L	88.9	Confident	88.9	Confident	5 Å²	5	30.8 Å²	30.8	3%	0.026	15%	0.152	C	C	.	.	H	α-helix	trans	-68.6	-41.7	176.3	-173.2	59.9	0	0	0	112	T286 V312 I316 S364 T369 L370 V371	T286-L367 HydrophobicContact CG2-CD1 4.35Å; T286-L367 HydrophobicContact CG2-CD2 4.2Å; T286-L367 WeakPolarHBondContact OG1-CD1 3.49Å; V312-L367 HydrophobicContact CB-CD2 4.18Å; V312-L367 HydrophobicContact CG1-CD2 3.87Å; V312-L367 HydrophobicContact CG2-CD2 4.33Å; I316-L367 HydrophobicContact CD1-CD2 4.32Å; I316-L367 HydrophobicContact CG1-CD2 3.8Å; I316-L367 HydrophobicContact CG1-CG 4.19Å; S364-L367 PolarHBondContact O-N 3.34Å; L367-T369 VanDerWaalsContact C-N 3.33Å; L367-T369 PolarHBondContact O-N 3.14Å; L367-L370 PolarHBondContact O-N 3.33Å; L367-V371 HydrophobicContact CD1-CG2 4.21Å; L367-V371 HydrophobicContact CG-CG2 4.42Å; L367-V371 WeakPolarHBondContact O-CG2 3.34Å; L367-V371 PolarHBondContact O-N 3.2Å
368	C	94.2	Very high	89.2	Confident	8 Å²	8	30.9 Å²	30.9	5%	0.054	16%	0.155	C	C	.	.	H	α-helix	trans	-55.5	-47.8	173	-179.8	0	0	0	0	111.3	G315 G319 A352 S364 L370 V371 L372	G315-C368 VanDerWaalsContact O-CA 3.28Å; G315-C368 WeakPolarHBondContact O-CA 3.32Å; G319-C368 WeakPolarHBondContact CA-O 3.46Å; G319-C368 PolarHBondContact N-SG 3.34Å; G319-C368 VanDerWaalsContact N-SG 3.43Å; A352-C368 HydrophobicContact CB-CB 4.11Å; S364-C368 WeakPolarHBondContact O-CB 3.4Å; S364-C368 PolarHBondContact O-N 3.43Å; C368-L370 PolarHBondContact O-N 3.01Å; C368-V371 PolarHBondContact O-N 2.86Å; C368-L372 WeakPolarHBondContact O-CB 3.2Å; C368-L372 PolarHBondContact O-N 3.09Å
369	T	93.3	Very high	89	Confident	0 Å²	0	22.6 Å²	22.6	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-56.2	-46.6	175.8	-65.6	0	0	0	0	112.8	S184 L187 S349 G365 G366 L367 A373	S184-T369 WeakPolarHBondContact O-CG2 3.43Å; L187-T369 HydrophobicContact CB-CG2 3.55Å; S349-T369 PolarHBondContact O-OG1 2.9Å; G365-T369 WeakPolarHBondContact O-CB 3.18Å; G365-T369 PolarHBondContact O-N 3.35Å; G365-T369 PolarHBondContact O-OG1 3.38Å; G366-T369 WeakPolarHBondContact O-CB 3.26Å; G366-T369 PolarHBondContact O-N 3.03Å; L367-T369 VanDerWaalsContact C-N 3.33Å; L367-T369 PolarHBondContact O-N 3.14Å; T369-A373 WeakPolarHBondContact O-CB 3.47Å; T369-A373 PolarHBondContact O-N 2.83Å; T369-A373 VanDerWaalsContact O-N 3.15Å
370	L	90.3	Very high	89	Confident	8 Å²	8	16.8 Å²	16.8	4%	0.042	10%	0.103	C	C	.	.	H	α-helix	trans	-66.4	-47	-179.3	-172.1	154.4	0	0	0	111.3	L194 I282 I285 G366 L367 C368 A373 F374	L194-L370 HydrophobicContact CD1-CD2 4.4Å; I282-L370 HydrophobicContact CG1-CD1 3.98Å; I282-L370 HydrophobicContact CG1-CD2 4.04Å; I285-L370 HydrophobicContact CD1-CD1 4.39Å; G366-L370 PolarHBondContact O-N 2.91Å; G366-L370 VanDerWaalsContact O-N 3.15Å; L367-L370 PolarHBondContact O-N 3.33Å; C368-L370 PolarHBondContact O-N 3.01Å; L370-A373 PolarHBondContact O-N 3.24Å; L370-F374 WeakPolarHBondContact O-CB 3.29Å; L370-F374 PolarHBondContact O-N 3.22Å
371	V	92.5	Very high	89	Confident	22 Å²	22	19.3 Å²	19.3	13%	0.133	12%	0.116	C	C	.	.	H	α-helix	trans	-68.8	-40.7	-178.4	177	0	0	0	0	111.3	I316 L367 C368 F374 V375	I316-V371 HydrophobicContact CG1-CG2 4.34Å; L367-V371 HydrophobicContact CD1-CG2 4.21Å; L367-V371 HydrophobicContact CG-CG2 4.42Å; L367-V371 WeakPolarHBondContact O-CG2 3.34Å; L367-V371 PolarHBondContact O-N 3.2Å; C368-V371 PolarHBondContact O-N 2.86Å; V371-F374 PolarHBondContact O-N 3.47Å; V371-V375 HydrophobicContact CG1-CG2 4Å; V371-V375 WeakPolarHBondContact O-CB 3.23Å; V371-V375 VanDerWaalsContact O-CG2 3.28Å; V371-V375 WeakPolarHBondContact O-CG2 3.11Å; V371-V375 PolarHBondContact O-N 3.49Å
372	L	95.4	Very high	88.8	Confident	0 Å²	0	21.2 Å²	21.2	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-50	-58.4	170.8	171.9	86.1	0	0	0	110.8	G319 L322 L326 L348 S349 C368 F374 V375 A376	G319-L372 VanDerWaalsContact O-CA 3.3Å; G319-L372 WeakPolarHBondContact O-CA 3.48Å; G319-L372 PolarHBondContact O-N 3.41Å; L322-L372 HydrophobicContact CB-CD1 3.28Å; L322-L372 HydrophobicContact CD1-CD1 4.5Å; L326-L372 HydrophobicContact CD1-CD1 3.89Å; L326-L372 HydrophobicContact CD1-CG 4.29Å; L326-L372 HydrophobicContact CG-CD1 4.35Å; L348-L372 HydrophobicContact CB-CD1 4.42Å; L348-L372 HydrophobicContact CB-CD2 3.95Å; L348-L372 HydrophobicContact CD1-CD1 4.41Å; S349-L372 WeakPolarHBondContact OG-CD2 3.39Å; C368-L372 WeakPolarHBondContact O-CB 3.2Å; C368-L372 PolarHBondContact O-N 3.09Å; L372-F374 VanDerWaalsContact C-N 3.35Å; L372-F374 PolarHBondContact O-N 3.37Å; L372-V375 PolarHBondContact O-N 3Å; L372-A376 VanDerWaalsContact O-CB 3.22Å; L372-A376 WeakPolarHBondContact O-CB 3.4Å; L372-A376 PolarHBondContact O-N 3.02Å
373	A	93.8	Very high	88.9	Confident	0 Å²	0	22.3 Å²	22.3	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-63.3	-40.3	-175.8	0	0	0	0	0	112.1	T188 L192 V345 T369 L370 G377	T188-A373 HydrophobicContact CG2-CB 4.21Å; T188-A373 WeakPolarHBondContact O-CB 3.5Å; L192-A373 HydrophobicContact CG-CB 4.26Å; V345-A373 HydrophobicContact CG1-CB 4.4Å; T369-A373 WeakPolarHBondContact O-CB 3.47Å; T369-A373 PolarHBondContact O-N 2.83Å; T369-A373 VanDerWaalsContact O-N 3.15Å; L370-A373 PolarHBondContact O-N 3.24Å; A373-G377 PolarHBondContact O-N 3.32Å
374	F	90.4	Very high	89.2	Confident	52 Å²	52	23.8 Å²	23.8	23%	0.228	14%	0.14	C	C	.	.	H	α-helix	trans	-64.5	-53.8	175.5	176.4	-117.7	0	0	0	112.6	G191 L194 P196 L370 V371 L372 A376 G377 V378	G191-F374 VanDerWaalsContact O-CA 3.3Å; G191-F374 WeakPolarHBondContact O-CA 3.19Å; L194-F374 HydrophobicContact CB-CD2 3.64Å; L194-F374 HydrophobicContact CB-CE2 3.83Å; L194-F374 HydrophobicContact CD1-CB 4.17Å; L194-F374 HydrophobicContact CD1-CD2 3.71Å; L194-F374 HydrophobicContact CD1-CE2 4.34Å; L194-F374 HydrophobicContact CD1-CG 4.04Å; L194-F374 HydrophobicContact CG-CD2 4.34Å; P196-F374 HydrophobicContact CB-CE2 4.47Å; P196-F374 HydrophobicContact CB-CZ 4.42Å; L370-F374 WeakPolarHBondContact O-CB 3.29Å; L370-F374 PolarHBondContact O-N 3.22Å; V371-F374 PolarHBondContact O-N 3.47Å; L372-F374 VanDerWaalsContact C-N 3.35Å; L372-F374 PolarHBondContact O-N 3.37Å; F374-A376 VanDerWaalsContact C-N 3.33Å; F374-A376 PolarHBondContact O-N 3.29Å; F374-G377 PolarHBondContact O-N 3.39Å; F374-V378 HydrophobicContact CD2-CG2 3.97Å; F374-V378 HydrophobicContact CE1-CG2 4.25Å; F374-V378 HydrophobicContact CE2-CG2 3.6Å; F374-V378 HydrophobicContact CG-CG2 4.47Å; F374-V378 HydrophobicContact CZ-CG2 3.76Å; F374-V378 VanDerWaalsContact O-CG2 3.27Å; F374-V378 WeakPolarHBondContact O-CG2 3.35Å; F374-V378 PolarHBondContact O-N 2.93Å
375	V	92.9	Very high	89.2	Confident	35 Å²	35	29.1 Å²	29.1	21%	0.212	16%	0.158	C	C	.	.	H	α-helix	trans	-65	-38.3	-175.3	172.8	0	0	0	0	111.4	I324 V371 L372	I324-V375 HydrophobicContact CG1-CG1 3.9Å; V371-V375 HydrophobicContact CG1-CG2 4Å; V371-V375 WeakPolarHBondContact O-CB 3.23Å; V371-V375 VanDerWaalsContact O-CG2 3.28Å; V371-V375 WeakPolarHBondContact O-CG2 3.11Å; V371-V375 PolarHBondContact O-N 3.49Å; L372-V375 PolarHBondContact O-N 3Å
376	A	93.2	Very high	89.3	Confident	0 Å²	0	30.6 Å²	30.6	0%	0	17%	0.171	C	C	.	.	H	α-helix	trans	-63.9	-49.8	172.3	0	0	0	0	0	111.1	L326 L372 F374 V378 G379 W380	L326-A376 HydrophobicContact CB-CB 3.86Å; L372-A376 VanDerWaalsContact O-CB 3.22Å; L372-A376 WeakPolarHBondContact O-CB 3.4Å; L372-A376 PolarHBondContact O-N 3.02Å; F374-A376 VanDerWaalsContact C-N 3.33Å; F374-A376 PolarHBondContact O-N 3.29Å; A376-V378 VanDerWaalsContact C-N 3.33Å; A376-V378 PolarHBondContact O-N 3.38Å; A376-G379 WeakPolarHBondContact O-CA 3.36Å; A376-G379 PolarHBondContact O-N 3Å; A376-W380 HydrophobicContact CB-CH2 3.6Å; A376-W380 HydrophobicContact CB-CZ2 3.73Å; A376-W380 HydrophobicContact CB-CZ3 4.12Å
377	G	89.8	Confident	89.6	Confident	3 Å²	3	30.4 Å²	30.4	3%	0.031	17%	0.169	C	C	.	.	H	α-helix	trans	-62.2	-31.5	180	0	0	0	0	0	114.9	A373 F374 G379 W380	A373-G377 PolarHBondContact O-N 3.32Å; F374-G377 PolarHBondContact O-N 3.39Å; G377-G379 PolarHBondContact O-N 3.39Å; G377-W380 PolarHBondContact O-N 2.86Å
378	V	88.8	Confident	89.7	Confident	61 Å²	61	32.9 Å²	32.9	37%	0.37	18%	0.18	S	C	.	.	H	α-helix	trans	-64.7	-24.3	172.9	169.6	0	0	0	0	112.1	P196 F374 A376	P196-V378 HydrophobicContact CB-CG2 4.18Å; P196-V378 HydrophobicContact CG-CG2 4.04Å; F374-V378 HydrophobicContact CD2-CG2 3.97Å; F374-V378 HydrophobicContact CE1-CG2 4.25Å; F374-V378 HydrophobicContact CE2-CG2 3.6Å; F374-V378 HydrophobicContact CG-CG2 4.47Å; F374-V378 HydrophobicContact CZ-CG2 3.76Å; F374-V378 VanDerWaalsContact O-CG2 3.27Å; F374-V378 WeakPolarHBondContact O-CG2 3.35Å; F374-V378 PolarHBondContact O-N 2.93Å; A376-V378 VanDerWaalsContact C-N 3.33Å; A376-V378 PolarHBondContact O-N 3.38Å
379	G	83.1	Confident	89.5	Confident	21 Å²	21	39.8 Å²	39.8	22%	0.216	21%	0.209	C	C	.	.	T	Hydrogen-bonded Turn	trans	-85.2	-8.5	178.2	0	0	0	0	0	115.5	A376 G377	A376-G379 WeakPolarHBondContact O-CA 3.36Å; A376-G379 PolarHBondContact O-N 3Å; G377-G379 PolarHBondContact O-N 3.39Å
380	W	87.4	Confident	89.6	Confident	15 Å²	15	41.1 Å²	41.1	6%	0.057	22%	0.216	C	C	.	.			trans	-111.9	143.2	-173.4	-55.3	-29	0	0	0	111.1	L192 L326 R341 V345 A376 G377 K384 V387	L192-W380 HydrophobicContact CD2-CZ3 4.06Å; L326-W380 HydrophobicContact CB-CZ2 4.26Å; L326-W380 WeakPolarHBondContact O-CZ2 3.13Å; L326-W380 PolarHBondContact O-NE1 3.21Å; R341-W380 HydrophobicContact CB-CH2 4.01Å; R341-W380 HydrophobicContact CB-CZ2 4.06Å; R341-W380 HydrophobicContact CG-CH2 4.31Å; R341-W380 HydrophobicContact CG-CZ2 3.84Å; R341-W380 VanDerWaalsContact CZ-CD1 3.45Å; V345-W380 HydrophobicContact CG2-CH2 3.5Å; V345-W380 VanDerWaalsContact CG2-CH2 3.5Å; V345-W380 HydrophobicContact CG2-CZ3 4.08Å; A376-W380 HydrophobicContact CB-CH2 3.6Å; A376-W380 HydrophobicContact CB-CZ2 3.73Å; A376-W380 HydrophobicContact CB-CZ3 4.12Å; G377-W380 PolarHBondContact O-N 2.86Å; W380-K384 HydrophobicContact CB-CB 4.12Å; W380-V387 HydrophobicContact CE3-CG2 4.39Å; W380-V387 HydrophobicContact CZ3-CB 4.38Å; W380-V387 HydrophobicContact CZ3-CG1 4.05Å; W380-V387 HydrophobicContact CZ3-CG2 4.18Å
381	S	81.5	Confident	89.7	Confident	84 Å²	84	40.8 Å²	40.8	59%	0.587	21%	0.214	S	C	*	.	S	Bend	trans	-91.6	-112.4	176.8	53.7	0	0	0	0	109.2	E383 K384	S381-E383 PolarHBondContact N-OE2 3.3Å; S381-E383 PolarHBondContact O-N 2.94Å; S381-E383 PolarHBondContact OG-OE2 2.87Å; S381-E383 VanDerWaalsContact OG-OE2 3.09Å; S381-K384 VanDerWaalsContact O-CB 3.26Å; S381-K384 WeakPolarHBondContact O-CB 3.41Å; S381-K384 PolarHBondContact O-N 3.33Å; S381-K384 VanDerWaalsContact O-N 3.16Å
382	D	80.7	Confident	89.7	Confident	106 Å²	106	40.9 Å²	40.9	57%	0.567	22%	0.218	S	C	*	.	H	α-helix	trans	-68.9	-19.5	-179.4	-68	-62.8	0	0	0	112.9	K384 R385 A386	D382-K384 PolarHBondContact O-N 2.97Å; D382-R385 PolarHBondContact O-N 3.11Å; D382-R385 IonicContact OD1-NH1 2.66Å; D382-R385 PolarHBondContact OD1-NH1 3.19Å; D382-R385 VanDerWaalsContact OD1-NH1 3.14Å; D382-A386 PolarHBondContact O-N 3.45Å
383	E	84.3	Confident	89.6	Confident	32 Å²	32	45.4 Å²	45.4	15%	0.15	25%	0.245	C	C	.	.	H	α-helix	trans	-67.2	-23.9	175	-38.1	98	121	0	0	111.7	H332 L337 R341 S381 R385 A386 V387	H332-E383 IonicContact CE1-OE1 2.94Å; H332-E383 PolarHBondContact CE1-OE1 3.31Å; H332-E383 IonicContact ND1-OE1 3.74Å; H332-E383 PolarHBondContact ND1-OE1 2.92Å; L337-E383 HydrophobicContact CD2-CG 4.33Å; R341-E383 IonicContact CZ-OE1 2.71Å; R341-E383 IonicContact NH1-OE1 3.89Å; R341-E383 PolarHBondContact NH1-OE1 3.17Å; R341-E383 IonicContact NH1-OE2 3.1Å; S381-E383 PolarHBondContact N-OE2 3.3Å; S381-E383 PolarHBondContact O-N 2.94Å; S381-E383 PolarHBondContact OG-OE2 2.87Å; S381-E383 VanDerWaalsContact OG-OE2 3.09Å; E383-R385 PolarHBondContact O-N 2.88Å; E383-A386 PolarHBondContact O-N 2.85Å; E383-V387 WeakPolarHBondContact O-CG2 3.44Å; E383-V387 PolarHBondContact O-N 3.06Å
384	K	88.3	Confident	89.6	Confident	33 Å²	33	46.4 Å²	46.4	14%	0.143	25%	0.254	C	S	.	.	H	α-helix	trans	-55.9	-50.6	171.9	-179.2	-179.2	170	168.1	0	110.6	L192 L194 W380 S381 D382 A386 V387 E388	L192-K384 WeakPolarHBondContact O-CE 3.18Å; L192-K384 PolarHBondContact O-NZ 2.9Å; L194-K384 PolarHBondContact O-NZ 3Å; W380-K384 HydrophobicContact CB-CB 4.12Å; S381-K384 VanDerWaalsContact O-CB 3.26Å; S381-K384 WeakPolarHBondContact O-CB 3.41Å; S381-K384 PolarHBondContact O-N 3.33Å; S381-K384 VanDerWaalsContact O-N 3.16Å; D382-K384 PolarHBondContact O-N 2.97Å; K384-A386 VanDerWaalsContact C-N 3.28Å; K384-A386 PolarHBondContact O-N 2.96Å; K384-V387 PolarHBondContact O-N 3.14Å; K384-E388 WeakPolarHBondContact CE-OE1 3.5Å; K384-E388 IonicContact NZ-OE1 3.26Å; K384-E388 WeakPolarHBondContact O-CB 3.16Å; K384-E388 WeakPolarHBondContact O-CG 3.16Å; K384-E388 PolarHBondContact O-N 3.39Å
385	R	88.3	Confident	89.7	Confident	121 Å²	121	44 Å²	44	46%	0.457	24%	0.243	S	C	.	.	H	α-helix	trans	-61.9	-35	177.7	-69.3	168.8	162	162.3	-15.3	111.8	E49 D382 E383 K389	E49-R385 IonicContact OE1-NH2 3.49Å; E49-R385 PolarHBondContact OE1-NH2 2.95Å; D382-R385 PolarHBondContact O-N 3.11Å; D382-R385 IonicContact OD1-NH1 2.66Å; D382-R385 PolarHBondContact OD1-NH1 3.19Å; D382-R385 VanDerWaalsContact OD1-NH1 3.14Å; E383-R385 PolarHBondContact O-N 2.88Å; R385-K389 VanDerWaalsContact O-CG 3.31Å; R385-K389 WeakPolarHBondContact O-CG 3.41Å; R385-K389 PolarHBondContact O-N 3.05Å; R385-K389 VanDerWaalsContact O-N 3.15Å
386	A	91.2	Very high	89.6	Confident	33 Å²	33	47.1 Å²	47.1	27%	0.273	26%	0.259	S	S	.	.	H	α-helix	trans	-69.5	-44.1	176.4	0	0	0	0	0	112	A338 D382 E383 K384 K389 I390	A338-A386 HydrophobicContact CB-CB 3.69Å; D382-A386 PolarHBondContact O-N 3.45Å; E383-A386 PolarHBondContact O-N 2.85Å; K384-A386 VanDerWaalsContact C-N 3.28Å; K384-A386 PolarHBondContact O-N 2.96Å; A386-K389 PolarHBondContact O-N 3.45Å; A386-I390 PolarHBondContact O-N 3.4Å
387	V	92.9	Very high	89.6	Confident	0 Å²	0	50.2 Å²	50.2	0%	0	28%	0.277	C	S	.	.	H	α-helix	trans	-63.7	-43.7	175.6	171.2	0	0	0	0	110.8	L192 R341 S342 W380 E383 K384 K389 I390 V391	L192-V387 HydrophobicContact CD1-CG1 3.85Å; L192-V387 HydrophobicContact CD2-CG1 4.39Å; R341-V387 HydrophobicContact CB-CG2 3.72Å; S342-V387 WeakPolarHBondContact OG-CA 3.24Å; W380-V387 HydrophobicContact CE3-CG2 4.39Å; W380-V387 HydrophobicContact CZ3-CB 4.38Å; W380-V387 HydrophobicContact CZ3-CG1 4.05Å; W380-V387 HydrophobicContact CZ3-CG2 4.18Å; E383-V387 WeakPolarHBondContact O-CG2 3.44Å; E383-V387 PolarHBondContact O-N 3.06Å; K384-V387 PolarHBondContact O-N 3.14Å; V387-K389 VanDerWaalsContact C-N 3.33Å; V387-K389 PolarHBondContact O-N 2.99Å; V387-I390 PolarHBondContact O-N 3.3Å; V387-I390 VanDerWaalsContact O-N 3.17Å; V387-V391 HydrophobicContact CG1-CG2 4.27Å; V387-V391 WeakPolarHBondContact O-CG2 3.09Å; V387-V391 PolarHBondContact O-N 3.07Å
388	E	90.9	Very high	89.8	Confident	57 Å²	57	52.4 Å²	52.4	27%	0.266	29%	0.286	S	S	.	.	H	α-helix	trans	-57.4	-41.3	175	-77.8	172.2	174.4	0	0	112.8	L192 K384 V391 A392	L192-E388 HydrophobicContact CB-CG 3.8Å; L192-E388 HydrophobicContact CD1-CG 4.15Å; L192-E388 HydrophobicContact CG-CG 4.49Å; K384-E388 WeakPolarHBondContact CE-OE1 3.5Å; K384-E388 IonicContact NZ-OE1 3.26Å; K384-E388 WeakPolarHBondContact O-CB 3.16Å; K384-E388 WeakPolarHBondContact O-CG 3.16Å; K384-E388 PolarHBondContact O-N 3.39Å; E388-V391 PolarHBondContact O-N 3.47Å; E388-A392 VanDerWaalsContact O-CB 3.28Å; E388-A392 WeakPolarHBondContact O-CB 3.22Å; E388-A392 PolarHBondContact O-N 2.88Å
389	K	91.4	Very high	90	Very high	152 Å²	152	50.9 Å²	50.9	66%	0.661	28%	0.275	S	S	*	.	H	α-helix	trans	-61.6	-43.9	175.1	-75.4	170.4	-176.3	179.2	0	111.7	R385 A386 V387 A392 V393	R385-K389 VanDerWaalsContact O-CG 3.31Å; R385-K389 WeakPolarHBondContact O-CG 3.41Å; R385-K389 PolarHBondContact O-N 3.05Å; R385-K389 VanDerWaalsContact O-N 3.15Å; A386-K389 PolarHBondContact O-N 3.45Å; V387-K389 VanDerWaalsContact C-N 3.33Å; V387-K389 PolarHBondContact O-N 2.99Å; K389-A392 PolarHBondContact O-N 3.1Å; K389-V393 WeakPolarHBondContact O-CG2 3.02Å; K389-V393 PolarHBondContact O-N 3Å
390	I	93.9	Very high	90.5	Very high	29 Å²	29	50 Å²	50	15%	0.149	27%	0.265	C	S	.	.	H	α-helix	trans	-66.9	-43.3	178.3	-63.4	164.5	0	0	0	110.7	A338 W339 S342 A386 V387 A392 V393 A394	A338-I390 HydrophobicContact CB-CD1 4.3Å; W339-I390 HydrophobicContact CD2-CD1 3.89Å; W339-I390 HydrophobicContact CE3-CD1 4.15Å; W339-I390 HydrophobicContact CE3-CG2 4.14Å; W339-I390 HydrophobicContact CG-CD1 4.14Å; W339-I390 HydrophobicContact CH2-CG2 4.43Å; W339-I390 HydrophobicContact CZ3-CG2 3.88Å; S342-I390 WeakPolarHBondContact OG-CB 3.4Å; S342-I390 WeakPolarHBondContact OG-CD1 3.18Å; A386-I390 PolarHBondContact O-N 3.4Å; V387-I390 PolarHBondContact O-N 3.3Å; V387-I390 VanDerWaalsContact O-N 3.17Å; I390-A392 VanDerWaalsContact C-N 3.3Å; I390-A392 PolarHBondContact O-N 3.48Å; I390-V393 PolarHBondContact O-N 3.33Å; I390-V393 VanDerWaalsContact O-N 3.17Å; I390-A394 PolarHBondContact O-N 2.85Å
391	V	94	Very high	90.8	Very high	0 Å²	0	50.4 Å²	50.4	0%	0	27%	0.267	C	S	.	.	H	α-helix	trans	-63.2	-36.1	174.8	173.4	0	0	0	0	111.3	I185 T188 R189 L192 L346 V387 E388 A394 W395	I185-V391 HydrophobicContact CG2-CG1 4.37Å; T188-V391 HydrophobicContact CG2-CG1 4.07Å; T188-V391 HydrophobicContact CG2-CG2 4.08Å; R189-V391 HydrophobicContact CB-CG1 3.87Å; R189-V391 HydrophobicContact CG-CG1 4.46Å; L192-V391 HydrophobicContact CD1-CB 4.37Å; L192-V391 HydrophobicContact CD1-CG2 3.9Å; L346-V391 HydrophobicContact CD1-CG2 4.35Å; L346-V391 HydrophobicContact CD2-CG1 4.4Å; L346-V391 HydrophobicContact CD2-CG2 4.07Å; L346-V391 HydrophobicContact CG-CG2 4.19Å; V387-V391 HydrophobicContact CG1-CG2 4.27Å; V387-V391 WeakPolarHBondContact O-CG2 3.09Å; V387-V391 PolarHBondContact O-N 3.07Å; E388-V391 PolarHBondContact O-N 3.47Å; V391-A394 PolarHBondContact O-N 3.04Å; V391-W395 WeakPolarHBondContact O-CB 3.45Å; V391-W395 PolarHBondContact O-N 2.77Å
392	A	90.9	Very high	91.3	Very high	25 Å²	25	46.4 Å²	46.4	21%	0.207	24%	0.239	C	C	.	.	H	α-helix	trans	-66.7	-35.3	174	0	0	0	0	0	112.6	E388 K389 I390 W395 N396	E388-A392 VanDerWaalsContact O-CB 3.28Å; E388-A392 WeakPolarHBondContact O-CB 3.22Å; E388-A392 PolarHBondContact O-N 2.88Å; K389-A392 PolarHBondContact O-N 3.1Å; I390-A392 VanDerWaalsContact C-N 3.3Å; I390-A392 PolarHBondContact O-N 3.48Å; A392-W395 PolarHBondContact O-N 2.98Å; A392-N396 PolarHBondContact O-N 3.44Å; A392-N396 PolarHBondContact O-ND2 2.83Å
393	V	93.3	Very high	91.9	Very high	94 Å²	94	41.3 Å²	41.3	57%	0.57	21%	0.212	S	C	*	.	H	α-helix	trans	-65.4	-46.5	171.6	172.4	0	0	0	0	110.9	K389 I390 W395 N396 V397	K389-V393 WeakPolarHBondContact O-CG2 3.02Å; K389-V393 PolarHBondContact O-N 3Å; I390-V393 PolarHBondContact O-N 3.33Å; I390-V393 VanDerWaalsContact O-N 3.17Å; V393-W395 VanDerWaalsContact C-N 3.3Å; V393-W395 PolarHBondContact O-N 2.92Å; V393-N396 PolarHBondContact O-N 3.38Å; V393-N396 VanDerWaalsContact O-N 3.17Å; V393-V397 PolarHBondContact O-N 3.41Å
394	A	94.1	Very high	92.3	Very high	22 Å²	22	39.8 Å²	39.8	18%	0.182	21%	0.205	C	C	.	.	H	α-helix	trans	-58.9	-42.2	174.4	0	0	0	0	0	111.7	I185 L346 I390 V391 N396 V397 F398	I185-A394 HydrophobicContact CD1-CB 4.49Å; I185-A394 HydrophobicContact CG2-CB 4.34Å; L346-A394 HydrophobicContact CD1-CB 4.11Å; I390-A394 PolarHBondContact O-N 2.85Å; V391-A394 PolarHBondContact O-N 3.04Å; A394-N396 PolarHBondContact O-N 3.39Å; A394-V397 WeakPolarHBondContact O-CB 3.36Å; A394-V397 PolarHBondContact O-N 3.44Å; A394-V397 VanDerWaalsContact O-N 3.15Å; A394-F398 PolarHBondContact O-N 3.11Å; A394-F398 VanDerWaalsContact O-N 3.08Å
395	W	92.9	Very high	92.6	Very high	1 Å²	1	38.3 Å²	38.3	0%	0.004	20%	0.199	C	C	.	.	H	α-helix	trans	-61.3	-41.7	174.8	176.2	-104.5	0	0	0	112.6	A182 I185 I186 V391 A392 V393 V397 F398 Q399 L402 F403 T464	A182-W395 HydrophobicContact CB-CZ3 4.33Å; I185-W395 HydrophobicContact CB-CE3 4.49Å; I185-W395 HydrophobicContact CG2-CB 3.85Å; I185-W395 HydrophobicContact CG2-CE3 4.13Å; I186-W395 HydrophobicContact CB-CE3 3.92Å; I186-W395 HydrophobicContact CB-CH2 3.9Å; I186-W395 HydrophobicContact CB-CZ3 3.57Å; I186-W395 HydrophobicContact CD1-CD2 4.15Å; I186-W395 HydrophobicContact CD1-CE3 4.34Å; I186-W395 HydrophobicContact CD1-CH2 4.18Å; I186-W395 HydrophobicContact CD1-CZ2 4Å; I186-W395 HydrophobicContact CD1-CZ3 4.37Å; I186-W395 HydrophobicContact CG1-CH2 4.11Å; I186-W395 HydrophobicContact CG1-CZ2 4.4Å; I186-W395 HydrophobicContact CG1-CZ3 4.25Å; I186-W395 HydrophobicContact CG2-CH2 4.47Å; I186-W395 HydrophobicContact CG2-CZ3 4.2Å; V391-W395 WeakPolarHBondContact O-CB 3.45Å; V391-W395 PolarHBondContact O-N 2.77Å; A392-W395 PolarHBondContact O-N 2.98Å; V393-W395 VanDerWaalsContact C-N 3.3Å; V393-W395 PolarHBondContact O-N 2.92Å; W395-V397 PolarHBondContact O-N 2.92Å; W395-F398 PolarHBondContact O-N 2.94Å; W395-F398 VanDerWaalsContact O-N 3.1Å; W395-Q399 HydrophobicContact CD2-CB 4.16Å; W395-Q399 HydrophobicContact CH2-CB 4.33Å; W395-Q399 HydrophobicContact CH2-CG 4.4Å; W395-Q399 HydrophobicContact CZ2-CB 3.84Å; W395-Q399 HydrophobicContact CZ2-CG 3.67Å; W395-Q399 WeakPolarHBondContact O-CB 3.41Å; W395-Q399 PolarHBondContact O-N 2.97Å; W395-L402 HydrophobicContact CH2-CD2 3.73Å; W395-L402 HydrophobicContact CZ3-CD2 4.26Å; W395-F403 HydrophobicContact CH2-CE2 4.42Å; W395-F403 HydrophobicContact CZ2-CE2 4.29Å; W395-T464 HydrophobicContact CZ2-CG2 4.36Å
396	N	91.4	Very high	92.7	Very high	101 Å²	101	32.6 Å²	32.6	54%	0.54	18%	0.177	S	C	.	.	H	α-helix	trans	-60.9	-26.6	176.8	-69.6	-27.3	0	0	0	113	A392 V393 A394 P400	A392-N396 PolarHBondContact O-N 3.44Å; A392-N396 PolarHBondContact O-ND2 2.83Å; V393-N396 PolarHBondContact O-N 3.38Å; V393-N396 VanDerWaalsContact O-N 3.17Å; A394-N396 PolarHBondContact O-N 3.39Å; N396-P400 WeakPolarHBondContact O-CD 3.43Å
397	V	92.8	Very high	92.7	Very high	65 Å²	65	31 Å²	31	39%	0.394	16%	0.164	S	C	.	.	H	α-helix	trans	-80	-38	173.5	179.3	0	0	0	0	112	Y124 V393 A394 W395 P400	Y124-V397 WeakPolarHBondContact CE2-O 3.25Å; V393-V397 PolarHBondContact O-N 3.41Å; A394-V397 WeakPolarHBondContact O-CB 3.36Å; A394-V397 PolarHBondContact O-N 3.44Å; A394-V397 VanDerWaalsContact O-N 3.15Å; W395-V397 PolarHBondContact O-N 2.92Å; V397-P400 WeakPolarHBondContact O-CD 3.42Å
398	F	93.6	Very high	92.6	Very high	48 Å²	48	31.7 Å²	31.7	21%	0.211	17%	0.169	C	C	.	.	H	α-helix	trans	-93.5	-16.8	-175.8	-80	-85.1	0	0	0	115.6	L178 I181 A182 I185 A394 W395 F401 L402	L178-F398 HydrophobicContact CD2-CE1 4.18Å; I181-F398 HydrophobicContact CB-CD1 4.24Å; I181-F398 HydrophobicContact CB-CE1 4.03Å; I181-F398 HydrophobicContact CD1-CE1 4.36Å; I181-F398 HydrophobicContact CG2-CD1 3.65Å; I181-F398 HydrophobicContact CG2-CD2 4.34Å; I181-F398 HydrophobicContact CG2-CE1 3.38Å; I181-F398 HydrophobicContact CG2-CE2 4.11Å; I181-F398 HydrophobicContact CG2-CG 4.13Å; I181-F398 HydrophobicContact CG2-CZ 3.63Å; A182-F398 HydrophobicContact CB-CB 3.98Å; I185-F398 HydrophobicContact CD1-CB 3.8Å; I185-F398 HydrophobicContact CD1-CD1 4.44Å; I185-F398 HydrophobicContact CD1-CD2 3.32Å; I185-F398 HydrophobicContact CD1-CE2 3.99Å; I185-F398 HydrophobicContact CD1-CG 3.59Å; A394-F398 PolarHBondContact O-N 3.11Å; A394-F398 VanDerWaalsContact O-N 3.08Å; W395-F398 PolarHBondContact O-N 2.94Å; W395-F398 VanDerWaalsContact O-N 3.1Å; F398-F401 AromaticContact CD1-CD2 3.97Å; F398-F401 HydrophobicContact CD1-CD2 3.97Å; F398-F401 HydrophobicContact CE1-CD2 4.31Å; F398-F401 WeakPolarHBondContact O-CB 3.38Å; F398-F401 PolarHBondContact O-N 3.09Å; F398-L402 PolarHBondContact O-N 2.71Å
399	Q	92.2	Very high	92.5	Very high	29 Å²	29	29.5 Å²	29.5	14%	0.136	16%	0.159	C	C	.	.	H	α-helix	trans	-57.4	-43.9	175.8	-176.5	-171.1	-75.7	0	0	113.1	L148 M151 W395 F401 L402 F403	L148-Q399 HydrophobicContact CD2-CG 3.65Å; M151-Q399 HydrophobicContact SD-CG 3.92Å; M151-Q399 PolarHBondContact SD-NE2 3.3Å; W395-Q399 HydrophobicContact CD2-CB 4.16Å; W395-Q399 HydrophobicContact CH2-CB 4.33Å; W395-Q399 HydrophobicContact CH2-CG 4.4Å; W395-Q399 HydrophobicContact CZ2-CB 3.84Å; W395-Q399 HydrophobicContact CZ2-CG 3.67Å; W395-Q399 WeakPolarHBondContact O-CB 3.41Å; W395-Q399 PolarHBondContact O-N 2.97Å; Q399-F401 VanDerWaalsContact C-N 3.31Å; Q399-F401 PolarHBondContact O-N 2.96Å; Q399-L402 PolarHBondContact O-N 2.81Å; Q399-F403 HydrophobicContact CG-CD2 3.96Å; Q399-F403 HydrophobicContact CG-CE2 4.16Å; Q399-F403 WeakPolarHBondContact O-CD2 3.01Å; Q399-F403 PolarHBondContact O-N 2.75Å; Q399-F403 VanDerWaalsContact O-N 3.17Å
400	P	94.1	Very high	92.3	Very high	2 Å²	2	22.3 Å²	22.3	1%	0.013	13%	0.128	C	C	.	.	H	α-helix	trans	-63.6	-35.1	176.3	-20.5	33.5	0	0	0	112.9	Y124 A127 V128 M151 N396 V397 G404	Y124-P400 HydrophobicContact CD2-CB 3.94Å; Y124-P400 HydrophobicContact CD2-CG 4.4Å; Y124-P400 HydrophobicContact CE2-CB 3.95Å; Y124-P400 HydrophobicContact CE2-CG 3.89Å; A127-P400 HydrophobicContact CB-CB 3.98Å; V128-P400 HydrophobicContact CG2-CB 3.86Å; V128-P400 HydrophobicContact CG2-CG 3.62Å; M151-P400 HydrophobicContact CE-CG 4.13Å; M151-P400 HydrophobicContact SD-CB 4.43Å; M151-P400 HydrophobicContact SD-CG 4.28Å; N396-P400 WeakPolarHBondContact O-CD 3.43Å; V397-P400 WeakPolarHBondContact O-CD 3.42Å; P400-G404 WeakPolarHBondContact O-CA 3.19Å; P400-G404 PolarHBondContact O-N 2.65Å
401	F	93.9	Very high	91.9	Very high	24 Å²	24	21.7 Å²	21.7	11%	0.105	13%	0.127	C	C	.	.	H	α-helix	trans	-64.2	-49.6	174	-72.6	-60.9	0	0	0	111.2	I120 Y124 L178 F398 Q399 L405	I120-F401 HydrophobicContact CG2-CD1 4.5Å; I120-F401 HydrophobicContact CG2-CE1 3.67Å; I120-F401 HydrophobicContact CG2-CZ 4.38Å; Y124-F401 HydrophobicContact CD2-CD1 4.25Å; Y124-F401 AromaticContact CD2-CD2 3.99Å; Y124-F401 HydrophobicContact CD2-CD2 3.99Å; Y124-F401 AromaticContact CD2-CE1 3.87Å; Y124-F401 HydrophobicContact CD2-CE1 3.87Å; Y124-F401 AromaticContact CD2-CE2 3.59Å; Y124-F401 HydrophobicContact CD2-CE2 3.59Å; Y124-F401 HydrophobicContact CD2-CG 4.3Å; Y124-F401 AromaticContact CD2-CZ 3.52Å; Y124-F401 HydrophobicContact CD2-CZ 3.52Å; Y124-F401 HydrophobicContact CE2-CD2 4.37Å; Y124-F401 AromaticContact CE2-CE2 3.99Å; Y124-F401 HydrophobicContact CE2-CE2 3.99Å; Y124-F401 HydrophobicContact CE2-CZ 4.31Å; Y124-F401 HydrophobicContact CG-CE1 4.1Å; Y124-F401 HydrophobicContact CG-CE2 4.36Å; Y124-F401 AromaticContact CG-CZ 3.86Å; Y124-F401 HydrophobicContact CG-CZ 3.86Å; L178-F401 HydrophobicContact CB-CB 4.46Å; L178-F401 HydrophobicContact CD1-CD1 4.05Å; L178-F401 HydrophobicContact CD1-CE1 4.23Å; L178-F401 HydrophobicContact CD2-CD1 4.45Å; L178-F401 HydrophobicContact CD2-CD2 4.37Å; L178-F401 HydrophobicContact CD2-CE2 4.5Å; L178-F401 HydrophobicContact CD2-CG 4.36Å; F398-F401 AromaticContact CD1-CD2 3.97Å; F398-F401 HydrophobicContact CD1-CD2 3.97Å; F398-F401 HydrophobicContact CE1-CD2 4.31Å; F398-F401 WeakPolarHBondContact O-CB 3.38Å; F398-F401 PolarHBondContact O-N 3.09Å; Q399-F401 VanDerWaalsContact C-N 3.31Å; Q399-F401 PolarHBondContact O-N 2.96Å; F401-L405 HydrophobicContact CB-CD1 4.21Å; F401-L405 WeakPolarHBondContact O-CB 3.49Å; F401-L405 WeakPolarHBondContact O-CD1 3.3Å; F401-L405 WeakPolarHBondContact O-CG 3.43Å; F401-L405 PolarHBondContact O-N 3.18Å
402	L	92.3	Very high	91.2	Very high	0 Å²	0	25.4 Å²	25.4	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-57.3	-58.8	-179	-173.4	68.1	0	0	0	111.5	R179 A182 W395 F398 Q399 I406 A467 A468	R179-L402 HydrophobicContact CB-CD1 4.33Å; R179-L402 HydrophobicContact CG-CD1 4.32Å; A182-L402 HydrophobicContact CB-CB 3.76Å; A182-L402 HydrophobicContact CB-CD1 4.16Å; A182-L402 HydrophobicContact CB-CG 4.37Å; W395-L402 HydrophobicContact CH2-CD2 3.73Å; W395-L402 HydrophobicContact CZ3-CD2 4.26Å; F398-L402 PolarHBondContact O-N 2.71Å; Q399-L402 PolarHBondContact O-N 2.81Å; L402-I406 HydrophobicContact CD1-CD1 3.84Å; L402-I406 HydrophobicContact CG-CD1 3.82Å; L402-I406 WeakPolarHBondContact O-CB 3.32Å; L402-I406 WeakPolarHBondContact O-CD1 3.49Å; L402-I406 WeakPolarHBondContact O-CG1 3.26Å; L402-I406 PolarHBondContact O-N 3.45Å; L402-I406 VanDerWaalsContact O-N 3.1Å; L402-A467 HydrophobicContact CD2-CB 3.97Å; L402-A467 HydrophobicContact CG-CB 4.27Å; L402-A468 HydrophobicContact CD2-CB 4.34Å
403	F	92.6	Very high	90.4	Very high	0 Å²	0	32.5 Å²	32.5	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-69.6	-38.9	-174.8	-75.4	-87.4	0	0	0	112.5	L148 M151 L152 W395 Q399 G407 T464 A467 I500	L148-F403 HydrophobicContact CB-CD1 4.15Å; L148-F403 HydrophobicContact CB-CE1 3.94Å; L148-F403 HydrophobicContact CB-CE2 4.4Å; L148-F403 HydrophobicContact CB-CG 4.45Å; L148-F403 HydrophobicContact CB-CZ 4.06Å; L148-F403 HydrophobicContact CD1-CZ 4.03Å; L148-F403 HydrophobicContact CD2-CD2 4Å; L148-F403 HydrophobicContact CD2-CE2 3.6Å; L148-F403 HydrophobicContact CD2-CZ 3.92Å; L148-F403 HydrophobicContact CG-CE2 4.38Å; L148-F403 HydrophobicContact CG-CZ 4.22Å; M151-F403 HydrophobicContact CB-CB 3.72Å; L152-F403 WeakPolarHBondContact CA-O 3.23Å; L152-F403 HydrophobicContact CB-CB 4.26Å; L152-F403 HydrophobicContact CB-CD1 4.23Å; L152-F403 HydrophobicContact CD1-CD1 4.34Å; W395-F403 HydrophobicContact CH2-CE2 4.42Å; W395-F403 HydrophobicContact CZ2-CE2 4.29Å; Q399-F403 HydrophobicContact CG-CD2 3.96Å; Q399-F403 HydrophobicContact CG-CE2 4.16Å; Q399-F403 WeakPolarHBondContact O-CD2 3.01Å; Q399-F403 PolarHBondContact O-N 2.75Å; Q399-F403 VanDerWaalsContact O-N 3.17Å; F403-G407 PolarHBondContact O-N 2.9Å; F403-T464 HydrophobicContact CE2-CG2 4.22Å; F403-T464 HydrophobicContact CZ-CG2 3.86Å; F403-A467 HydrophobicContact CD1-CB 4.15Å; F403-A467 HydrophobicContact CE1-CB 3.58Å; F403-A467 HydrophobicContact CE2-CB 4.28Å; F403-A467 HydrophobicContact CZ-CB 3.66Å; F403-I500 HydrophobicContact CE1-CG2 4.35Å
404	G	94.1	Very high	89.2	Confident	0 Å²	0	32.1 Å²	32.1	0%	0	18%	0.181	C	C	.	.	H	α-helix	trans	-64.2	-47	176.4	0	0	0	0	0	112.6	M151 G155 P400 I406 G407 A408	M151-G404 WeakPolarHBondContact O-CA 3.22Å; G155-G404 VanDerWaalsContact CA-O 3.29Å; G155-G404 WeakPolarHBondContact CA-O 3.48Å; P400-G404 WeakPolarHBondContact O-CA 3.19Å; P400-G404 PolarHBondContact O-N 2.65Å; G404-I406 VanDerWaalsContact C-N 3.32Å; G404-I406 PolarHBondContact O-N 3.36Å; G404-G407 PolarHBondContact O-N 3.19Å; G404-A408 WeakPolarHBondContact O-CB 3.4Å; G404-A408 PolarHBondContact O-N 3.39Å
405	L	92.9	Very high	88.3	Confident	2 Å²	2	32.8 Å²	32.8	1%	0.01	18%	0.182	C	C	.	.	H	α-helix	trans	-66.6	-34.1	179.7	-68	166.5	0	0	0	112	L123 I170 L178 R179 F401 A408 E409	L123-L405 HydrophobicContact CD1-CD2 3.88Å; L123-L405 HydrophobicContact CD1-CG 4.4Å; L123-L405 HydrophobicContact CD2-CD2 4.13Å; L123-L405 HydrophobicContact CD2-CG 4.04Å; I170-L405 HydrophobicContact CD1-CD2 4.19Å; I170-L405 HydrophobicContact CG2-CD2 4.11Å; L178-L405 HydrophobicContact CB-CD1 3.56Å; L178-L405 HydrophobicContact CD1-CD1 4.14Å; R179-L405 HydrophobicContact CG-CB 4.16Å; R179-L405 HydrophobicContact CG-CD1 4.21Å; F401-L405 HydrophobicContact CB-CD1 4.21Å; F401-L405 WeakPolarHBondContact O-CB 3.49Å; F401-L405 WeakPolarHBondContact O-CD1 3.3Å; F401-L405 WeakPolarHBondContact O-CG 3.43Å; F401-L405 PolarHBondContact O-N 3.18Å; L405-A408 PolarHBondContact O-N 3.39Å; L405-E409 WeakPolarHBondContact O-CG 3.37Å; L405-E409 PolarHBondContact O-N 3.42Å
406	I	91.4	Very high	87.6	Confident	1 Å²	1	39 Å²	39	1%	0.005	21%	0.205	C	C	.	.	H	α-helix	trans	-67.1	-44.8	174.3	-70.6	162.4	0	0	0	111.3	L402 G404 A408 E409 A467 L493	L402-I406 HydrophobicContact CD1-CD1 3.84Å; L402-I406 HydrophobicContact CG-CD1 3.82Å; L402-I406 WeakPolarHBondContact O-CB 3.32Å; L402-I406 WeakPolarHBondContact O-CD1 3.49Å; L402-I406 WeakPolarHBondContact O-CG1 3.26Å; L402-I406 PolarHBondContact O-N 3.45Å; L402-I406 VanDerWaalsContact O-N 3.1Å; G404-I406 VanDerWaalsContact C-N 3.32Å; G404-I406 PolarHBondContact O-N 3.36Å; I406-A408 PolarHBondContact O-N 2.94Å; I406-E409 PolarHBondContact O-N 2.9Å; I406-A467 HydrophobicContact CD1-CB 3.59Å; I406-A467 WeakPolarHBondContact CD1-O 3.37Å; I406-L493 HydrophobicContact CG2-CD1 4.08Å
407	G	91.9	Very high	87.1	Confident	0 Å²	0	39.7 Å²	39.7	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-57.8	-38.8	172.3	0	0	0	0	0	112.1	L152 F156 F403 G404 E409 V410	L152-G407 WeakPolarHBondContact O-CA 3.36Å; F156-G407 VanDerWaalsContact CA-O 3.27Å; F156-G407 WeakPolarHBondContact CA-O 3.33Å; F156-G407 PolarHBondContact N-O 3.17Å; F403-G407 PolarHBondContact O-N 2.9Å; G404-G407 PolarHBondContact O-N 3.19Å; G407-E409 PolarHBondContact O-N 2.7Å; G407-V410 PolarHBondContact O-N 3.32Å
408	A	90.9	Very high	86.6	Confident	13 Å²	13	43.8 Å²	43.8	11%	0.107	23%	0.23	C	C	.	.	H	α-helix	trans	-75.5	-13.8	-178	0	0	0	0	0	115.4	L123 G155 R159 G404 L405 I406	L123-A408 HydrophobicContact CD1-CB 3.71Å; G155-A408 WeakPolarHBondContact O-CA 3.21Å; R159-A408 WeakPolarHBondContact CB-O 3.48Å; R159-A408 VanDerWaalsContact CD-O 3.31Å; R159-A408 WeakPolarHBondContact CD-O 3.45Å; R159-A408 VanDerWaalsContact CG-O 3.22Å; R159-A408 WeakPolarHBondContact CG-O 3.08Å; G404-A408 WeakPolarHBondContact O-CB 3.4Å; G404-A408 PolarHBondContact O-N 3.39Å; L405-A408 PolarHBondContact O-N 3.39Å; I406-A408 PolarHBondContact O-N 2.94Å
409	E	88.1	Confident	85.9	Confident	11 Å²	11	42.5 Å²	42.5	5%	0.051	23%	0.226	C	C	.	.	H	α-helix	trans	-79.3	-28.1	169.9	-67.4	-83.8	176.4	0	0	111.9	R179 L405 I406 G407 S411 R478 L493	R179-E409 IonicContact CZ-OE1 2.77Å; R179-E409 VanDerWaalsContact CZ-OE1 3.26Å; R179-E409 IonicContact NH1-OE1 3.47Å; R179-E409 PolarHBondContact NH1-OE1 2.93Å; R179-E409 IonicContact NH2-OE1 3.62Å; R179-E409 PolarHBondContact NH2-OE1 2.74Å; L405-E409 WeakPolarHBondContact O-CG 3.37Å; L405-E409 PolarHBondContact O-N 3.42Å; I406-E409 PolarHBondContact O-N 2.9Å; G407-E409 PolarHBondContact O-N 2.7Å; E409-S411 PolarHBondContact O-N 3.36Å; E409-R478 VanDerWaalsContact CD-NH1 3.29Å; E409-R478 IonicContact OE1-NH1 3.5Å; E409-R478 PolarHBondContact OE1-NH1 3.44Å; E409-R478 IonicContact OE2-CZ 2.71Å; E409-R478 IonicContact OE2-NH1 3.77Å; E409-R478 PolarHBondContact OE2-NH1 3.47Å; E409-R478 IonicContact OE2-NH2 3.91Å; E409-R478 PolarHBondContact OE2-NH2 3.22Å; E409-L493 HydrophobicContact CB-CD2 3.72Å; E409-L493 HydrophobicContact CG-CD2 4.07Å
410	V	87.7	Confident	85.6	Confident	1 Å²	1	42.8 Å²	42.8	1%	0.006	23%	0.229	C	C	.	.			trans	-85.5	104.2	-170.2	-178.2	0	0	0	0	111.2	F156 N160 G407 L415 F497	F156-V410 HydrophobicContact CD2-CB 4.41Å; F156-V410 HydrophobicContact CD2-CG1 4.36Å; F156-V410 HydrophobicContact CE2-CG1 4.26Å; N160-V410 PolarHBondContact ND2-O 3.21Å; G407-V410 PolarHBondContact O-N 3.32Å; V410-L415 HydrophobicContact CG1-CD1 3.79Å; V410-F497 HydrophobicContact CB-CD2 4.21Å; V410-F497 HydrophobicContact CB-CE2 4.37Å; V410-F497 HydrophobicContact CB-CG 4.31Å; V410-F497 HydrophobicContact CG1-CD1 4.01Å; V410-F497 HydrophobicContact CG1-CE1 4.16Å; V410-F497 HydrophobicContact CG1-CG 4.23Å; V410-F497 HydrophobicContact CG1-CZ 4.48Å; V410-F497 HydrophobicContact CG2-CB 3.89Å; V410-F497 HydrophobicContact CG2-CD1 4.4Å; V410-F497 HydrophobicContact CG2-CD2 3.81Å; V410-F497 HydrophobicContact CG2-CE2 4.45Å; V410-F497 HydrophobicContact CG2-CG 3.79Å
411	S	83.9	Confident	85.3	Confident	17 Å²	17	44.6 Å²	44.6	12%	0.119	25%	0.249	C	C	.	.			trans	-99.2	117.2	179	171.6	0	0	0	0	111.7	E409 M413 S414 L415	E409-S411 PolarHBondContact O-N 3.36Å; S411-M413 PolarHBondContact O-N 3.05Å; S411-M413 PolarHBondContact OG-N 3.24Å; S411-S414 WeakPolarHBondContact CB-OG 2.75Å; S411-S414 PolarHBondContact O-N 2.95Å; S411-S414 VanDerWaalsContact O-N 3.08Å; S411-S414 PolarHBondContact OG-N 2.99Å; S411-S414 PolarHBondContact OG-OG 2.77Å; S411-L415 WeakPolarHBondContact O-CG 3.34Å; S411-L415 PolarHBondContact O-N 3.42Å
412	V	80.6	Confident	85.1	Confident	77 Å²	77	46.7 Å²	46.7	47%	0.467	26%	0.261	S	S	.	.	G	3₁₀ helix	trans	-58.3	-35.5	173.1	177	0	0	0	0	111.2	F156 N160 S414 L415	F156-V412 HydrophobicContact CE1-CG2 4.42Å; F156-V412 HydrophobicContact CE2-CG2 3.71Å; F156-V412 HydrophobicContact CZ-CG2 3.37Å; N160-V412 WeakPolarHBondContact OD1-CB 3.35Å; N160-V412 WeakPolarHBondContact OD1-CG2 3.46Å; N160-V412 PolarHBondContact OD1-N 2.83Å; V412-S414 PolarHBondContact O-N 2.66Å; V412-L415 PolarHBondContact O-N 3.04Å
413	M	73.1	Confident	84.8	Confident	175 Å²	175	46.7 Å²	46.7	86%	0.862	26%	0.261	S	S	*	.	G	3₁₀ helix	trans	-67.2	-21.8	179.5	-147.8	63.4	62.7	0	0	113	S411	S411-M413 PolarHBondContact O-N 3.05Å; S411-M413 PolarHBondContact OG-N 3.24Å
414	S	69.4	Low	84.7	Confident	85 Å²	85	50.4 Å²	50.4	59%	0.594	28%	0.28	S	S	*	.	G	3₁₀ helix	trans	-92	-13.2	175.7	-52	0	0	0	0	112.5	S411 V412	S411-S414 WeakPolarHBondContact CB-OG 2.75Å; S411-S414 PolarHBondContact O-N 2.95Å; S411-S414 VanDerWaalsContact O-N 3.08Å; S411-S414 PolarHBondContact OG-N 2.99Å; S411-S414 PolarHBondContact OG-OG 2.77Å; V412-S414 PolarHBondContact O-N 2.66Å
415	L	74.8	Confident	84.7	Confident	36 Å²	36	52.2 Å²	52.2	19%	0.188	30%	0.295	C	S	.	.			trans	-96.1	104.2	-176.4	-72	174.6	0	0	0	111.3	V410 S411 V412 V420 T494	V410-L415 HydrophobicContact CG1-CD1 3.79Å; S411-L415 WeakPolarHBondContact O-CG 3.34Å; S411-L415 PolarHBondContact O-N 3.42Å; V412-L415 PolarHBondContact O-N 3.04Å; L415-V420 HydrophobicContact CB-CG2 3.85Å; L415-V420 HydrophobicContact CD1-CG2 4.25Å; L415-V420 HydrophobicContact CD2-CG2 4.28Å; L415-V420 HydrophobicContact CG-CG2 4.36Å; L415-T494 HydrophobicContact CD1-CG2 4.3Å; L415-T494 HydrophobicContact CD2-CG2 3.44Å; L415-T494 VanDerWaalsContact CD2-CG2 3.44Å
416	R	78.3	Confident	84.6	Confident	133 Å²	133	52.1 Å²	52.1	50%	0.502	30%	0.295	S	S	.	.			trans	-60.9	129.9	167.5	-68.4	179.9	-59.4	-75.3	-17.3	109.3	E418 T419 V420	R416-E418 PolarHBondContact O-N 2.92Å; R416-E418 VanDerWaalsContact O-N 3.15Å; R416-T419 PolarHBondContact NE-OG1 3.33Å; R416-T419 PolarHBondContact NH2-OG1 2.91Å; R416-T419 PolarHBondContact O-N 2.96Å; R416-V420 PolarHBondContact O-N 3.42Å; R416-V420 VanDerWaalsContact O-N 3.13Å
417	P	80.9	Confident	84.7	Confident	114 Å²	114	52.3 Å²	52.3	74%	0.74	30%	0.295	S	S	*	.	H	α-helix	trans	-54.6	-35.3	179.6	-29	35.9	0	0	0	113.8	V420 G421	P417-V420 PolarHBondContact O-N 2.73Å; P417-G421 PolarHBondContact O-N 3.46Å
418	E	82	Confident	84.8	Confident	152 Å²	152	53.8 Å²	53.8	71%	0.71	31%	0.311	S	S	*	.	H	α-helix	trans	-58.5	-48.4	174	-63.7	168.8	-173.1	0	0	112	R416 V420 G421 L422	R416-E418 PolarHBondContact O-N 2.92Å; R416-E418 VanDerWaalsContact O-N 3.15Å; E418-V420 VanDerWaalsContact C-N 3.33Å; E418-V420 PolarHBondContact O-N 3.27Å; E418-G421 PolarHBondContact O-N 2.87Å; E418-L422 WeakPolarHBondContact O-CG 3.48Å; E418-L422 PolarHBondContact O-N 2.8Å
419	T	79.9	Confident	85.1	Confident	21 Å²	21	56.8 Å²	56.8	13%	0.129	32%	0.324	C	S	.	.	H	α-helix	trans	-64	-39.2	178.2	-56.1	0	0	0	0	110.9	R416 L422 C423	R416-T419 PolarHBondContact NE-OG1 3.33Å; R416-T419 PolarHBondContact NH2-OG1 2.91Å; R416-T419 PolarHBondContact O-N 2.96Å; T419-L422 PolarHBondContact O-N 3.46Å; T419-C423 PolarHBondContact O-N 3Å; T419-C423 PolarHBondContact O-SG 3.48Å
420	V	85.4	Confident	85.4	Confident	34 Å²	34	56.2 Å²	56.2	21%	0.206	32%	0.322	C	S	.	.	H	α-helix	trans	-62.7	-42.1	173.5	176.9	0	0	0	0	111.6	L415 R416 P417 E418 L422 C423 I424 L498	L415-V420 HydrophobicContact CB-CG2 3.85Å; L415-V420 HydrophobicContact CD1-CG2 4.25Å; L415-V420 HydrophobicContact CD2-CG2 4.28Å; L415-V420 HydrophobicContact CG-CG2 4.36Å; R416-V420 PolarHBondContact O-N 3.42Å; R416-V420 VanDerWaalsContact O-N 3.13Å; P417-V420 PolarHBondContact O-N 2.73Å; E418-V420 VanDerWaalsContact C-N 3.33Å; E418-V420 PolarHBondContact O-N 3.27Å; V420-L422 PolarHBondContact O-N 2.91Å; V420-C423 WeakPolarHBondContact O-CB 3.47Å; V420-C423 PolarHBondContact O-N 3.29Å; V420-I424 HydrophobicContact CG1-CD1 3.95Å; V420-I424 WeakPolarHBondContact O-CG1 3.29Å; V420-I424 PolarHBondContact O-N 3.07Å; V420-L498 HydrophobicContact CG1-CD1 4.11Å; V420-L498 HydrophobicContact CG1-CD2 4.41Å
421	G	88.3	Confident	85.7	Confident	41 Å²	41	57.2 Å²	57.2	42%	0.423	33%	0.327	S	S	.	.	H	α-helix	trans	-59.2	-44.5	174.8	0	0	0	0	0	112.6	P417 E418 I424 A425	P417-G421 PolarHBondContact O-N 3.46Å; E418-G421 PolarHBondContact O-N 2.87Å; G421-I424 PolarHBondContact O-N 3.3Å; G421-A425 WeakPolarHBondContact O-CB 3.3Å; G421-A425 PolarHBondContact O-N 3.26Å
422	L	88.2	Confident	86.3	Confident	67 Å²	67	60.3 Å²	60.3	35%	0.351	35%	0.345	S	S	.	.	H	α-helix	trans	-64.8	-39.2	175.4	-65.2	168.4	0	0	0	112.1	F228 E418 T419 V420 I424 A425 T426	F228-L422 HydrophobicContact CB-CB 4.46Å; F228-L422 HydrophobicContact CB-CD2 4.17Å; F228-L422 HydrophobicContact CD2-CD2 4.49Å; F228-L422 HydrophobicContact CG-CD2 4.29Å; E418-L422 WeakPolarHBondContact O-CG 3.48Å; E418-L422 PolarHBondContact O-N 2.8Å; T419-L422 PolarHBondContact O-N 3.46Å; V420-L422 PolarHBondContact O-N 2.91Å; L422-I424 PolarHBondContact O-N 3.33Å; L422-A425 PolarHBondContact O-N 3.25Å; L422-T426 WeakPolarHBondContact O-CB 3.41Å; L422-T426 PolarHBondContact O-N 3.48Å; L422-T426 PolarHBondContact O-OG1 3.31Å
423	C	87	Confident	87.1	Confident	1 Å²	1	58.8 Å²	58.8	1%	0.007	34%	0.335	C	S	.	.	H	α-helix	trans	-59.9	-45.3	173.9	-65.9	0	0	0	0	111.9	T419 V420 T426 L427 V495 L498	T419-C423 PolarHBondContact O-N 3Å; T419-C423 PolarHBondContact O-SG 3.48Å; V420-C423 WeakPolarHBondContact O-CB 3.47Å; V420-C423 PolarHBondContact O-N 3.29Å; C423-T426 PolarHBondContact O-N 3.23Å; C423-L427 WeakPolarHBondContact O-CB 3.36Å; C423-L427 PolarHBondContact O-N 2.88Å; C423-V495 HydrophobicContact CB-CG2 3.81Å; C423-V495 WeakPolarHBondContact SG-CG2 3.46Å; C423-L498 HydrophobicContact CB-CD1 3.61Å
424	I	91	Very high	88.1	Confident	77 Å²	77	50.5 Å²	50.5	40%	0.395	30%	0.295	S	S	.	.	H	α-helix	trans	-67.1	-39.1	178.4	-66.7	169	0	0	0	110.9	V420 G421 L422 L427 G428 L498 I502	V420-I424 HydrophobicContact CG1-CD1 3.95Å; V420-I424 WeakPolarHBondContact O-CG1 3.29Å; V420-I424 PolarHBondContact O-N 3.07Å; G421-I424 PolarHBondContact O-N 3.3Å; L422-I424 PolarHBondContact O-N 3.33Å; I424-L427 PolarHBondContact O-N 3.43Å; I424-G428 PolarHBondContact O-N 2.93Å; I424-L498 HydrophobicContact CG1-CD1 4.42Å; I424-I502 HydrophobicContact CD1-CD1 4.42Å; I424-I502 HydrophobicContact CG1-CD1 4.09Å
425	A	92.4	Very high	89.3	Confident	39 Å²	39	48.8 Å²	48.8	32%	0.322	28%	0.278	S	S	.	.	H	α-helix	trans	-63	-47.3	175	0	0	0	0	0	111.9	F228 G421 L422 L427 G428 I429	F228-A425 HydrophobicContact CE2-CB 4.38Å; G421-A425 WeakPolarHBondContact O-CB 3.3Å; G421-A425 PolarHBondContact O-N 3.26Å; L422-A425 PolarHBondContact O-N 3.25Å; A425-L427 PolarHBondContact O-N 2.89Å; A425-G428 PolarHBondContact O-N 3.47Å; A425-I429 WeakPolarHBondContact O-CG1 3.16Å; A425-I429 PolarHBondContact O-N 3.44Å
426	T	92.3	Very high	90.3	Very high	0 Å²	0	52.1 Å²	52.1	0%	0	30%	0.296	C	S	.	.	H	α-helix	trans	-56.3	-49.9	174.8	-67.7	0	0	0	0	111.4	L224 L422 C423 G428 A430	L224-T426 HydrophobicContact CB-CG2 3.89Å; L224-T426 HydrophobicContact CD1-CG2 4.49Å; L422-T426 WeakPolarHBondContact O-CB 3.41Å; L422-T426 PolarHBondContact O-N 3.48Å; L422-T426 PolarHBondContact O-OG1 3.31Å; C423-T426 PolarHBondContact O-N 3.23Å; T426-G428 PolarHBondContact O-N 2.9Å; T426-A430 WeakPolarHBondContact O-CB 3.27Å; T426-A430 PolarHBondContact O-N 3.37Å
427	L	93.4	Very high	91.1	Very high	4 Å²	4	46.4 Å²	46.4	2%	0.021	28%	0.277	C	S	.	.	H	α-helix	trans	-59.3	-46.7	176.9	175.4	65.3	0	0	0	112.1	L243 C423 I424 A425 L431 K462 A499 I502 T503	L243-L427 HydrophobicContact CD2-CD1 4.01Å; C423-L427 WeakPolarHBondContact O-CB 3.36Å; C423-L427 PolarHBondContact O-N 2.88Å; I424-L427 PolarHBondContact O-N 3.43Å; A425-L427 PolarHBondContact O-N 2.89Å; L427-L431 HydrophobicContact CD1-CD1 3.87Å; L427-L431 HydrophobicContact CD1-CG 4.2Å; L427-L431 HydrophobicContact CG-CD1 3.89Å; L427-L431 WeakPolarHBondContact O-CB 3.39Å; L427-L431 WeakPolarHBondContact O-CD1 3.31Å; L427-L431 VanDerWaalsContact O-CG 3.26Å; L427-L431 WeakPolarHBondContact O-CG 3.26Å; L427-L431 PolarHBondContact O-N 2.87Å; L427-K462 HydrophobicContact CD1-CD 4.09Å; L427-A499 HydrophobicContact CD1-CB 3.75Å; L427-A499 HydrophobicContact CD2-CB 4.09Å; L427-I502 HydrophobicContact CD2-CD1 4.31Å; L427-T503 HydrophobicContact CD1-CG2 4.31Å; L427-T503 HydrophobicContact CD2-CG2 4.27Å
428	G	94.4	Very high	91.7	Very high	32 Å²	32	41 Å²	41	33%	0.33	24%	0.242	S	C	.	.	H	α-helix	trans	-63.7	-46.5	-177.8	0	0	0	0	0	112.9	I424 A425 T426 L431 V432	I424-G428 PolarHBondContact O-N 2.93Å; A425-G428 PolarHBondContact O-N 3.47Å; T426-G428 PolarHBondContact O-N 2.9Å; G428-L431 PolarHBondContact O-N 3.27Å; G428-V432 WeakPolarHBondContact O-CG2 3.31Å; G428-V432 PolarHBondContact O-N 3.48Å
429	I	95.7	Very high	92.3	Very high	75 Å²	75	36.4 Å²	36.4	39%	0.385	22%	0.22	S	C	.	.	H	α-helix	trans	-67.4	-43.3	179.1	-61.6	164.3	0	0	0	110.4	T220 L224 F228 A425 L431 V432 V433	T220-I429 HydrophobicContact CG2-CG2 4.21Å; L224-I429 HydrophobicContact CD1-CB 3.68Å; L224-I429 HydrophobicContact CD1-CD1 4.26Å; L224-I429 HydrophobicContact CD1-CG2 3.69Å; L224-I429 HydrophobicContact CD2-CD1 4.28Å; F228-I429 HydrophobicContact CE2-CD1 4.18Å; F228-I429 HydrophobicContact CZ-CD1 4.5Å; A425-I429 WeakPolarHBondContact O-CG1 3.16Å; A425-I429 PolarHBondContact O-N 3.44Å; I429-L431 VanDerWaalsContact C-N 3.35Å; I429-L431 PolarHBondContact O-N 3.06Å; I429-V432 PolarHBondContact O-N 2.81Å; I429-V433 PolarHBondContact O-N 2.7Å
430	A	95	Very high	92.9	Very high	0 Å²	0	40.6 Å²	40.6	0%	0	24%	0.241	C	C	.	.	H	α-helix	trans	-59.9	-43.5	177.2	0	0	0	0	0	111.9	E217 T220 A221 T426 V433 R434	E217-A430 HydrophobicContact CG-CB 3.86Å; T220-A430 HydrophobicContact CG2-CB 4.39Å; A221-A430 HydrophobicContact CB-CB 4.13Å; T426-A430 WeakPolarHBondContact O-CB 3.27Å; T426-A430 PolarHBondContact O-N 3.37Å; A430-V433 PolarHBondContact O-N 2.83Å; A430-R434 PolarHBondContact O-N 2.89Å
431	L	94.6	Very high	93.2	Very high	21 Å²	21	42 Å²	42	11%	0.11	25%	0.246	C	C	.	.	H	α-helix	trans	-62.4	-40.7	174.3	-77.8	167.3	0	0	0	113.2	L427 G428 I429 V433 R434 I435 I460 T503	L427-L431 HydrophobicContact CD1-CD1 3.87Å; L427-L431 HydrophobicContact CD1-CG 4.2Å; L427-L431 HydrophobicContact CG-CD1 3.89Å; L427-L431 WeakPolarHBondContact O-CB 3.39Å; L427-L431 WeakPolarHBondContact O-CD1 3.31Å; L427-L431 VanDerWaalsContact O-CG 3.26Å; L427-L431 WeakPolarHBondContact O-CG 3.26Å; L427-L431 PolarHBondContact O-N 2.87Å; G428-L431 PolarHBondContact O-N 3.27Å; I429-L431 VanDerWaalsContact C-N 3.35Å; I429-L431 PolarHBondContact O-N 3.06Å; L431-V433 VanDerWaalsContact C-N 3.35Å; L431-R434 WeakPolarHBondContact O-CB 3.46Å; L431-R434 PolarHBondContact O-N 3.34Å; L431-I435 VanDerWaalsContact O-CG1 3.3Å; L431-I435 WeakPolarHBondContact O-CG1 3.41Å; L431-I435 PolarHBondContact O-N 3.36Å; L431-I460 HydrophobicContact CD2-CG2 4.48Å; L431-T503 HydrophobicContact CD1-CG2 3.66Å
432	V	96	Very high	93.2	Very high	83 Å²	83	40.1 Å²	40.1	50%	0.503	23%	0.226	S	C	.	.	H	α-helix	trans	-61.8	-44.9	176.2	168.9	0	0	0	0	110.4	G428 I429 R434 I435 L436	G428-V432 WeakPolarHBondContact O-CG2 3.31Å; G428-V432 PolarHBondContact O-N 3.48Å; I429-V432 PolarHBondContact O-N 2.81Å; V432-R434 VanDerWaalsContact C-N 3.34Å; V432-R434 PolarHBondContact O-N 3.48Å; V432-I435 PolarHBondContact O-N 3.17Å; V432-L436 HydrophobicContact CG1-CD1 4.1Å; V432-L436 WeakPolarHBondContact O-CG 3.48Å; V432-L436 PolarHBondContact O-N 3.45Å; V432-L436 VanDerWaalsContact O-N 3.07Å
433	V	96.6	Very high	93	Very high	44 Å²	44	38.9 Å²	38.9	27%	0.267	22%	0.222	S	C	.	.	H	α-helix	trans	-62.5	-41.5	174.6	176.9	0	0	0	0	111.1	T220 I429 A430 L431 I435 L436 A437	T220-V433 HydrophobicContact CG2-CB 4.31Å; T220-V433 HydrophobicContact CG2-CG2 3.91Å; T220-V433 WeakPolarHBondContact OG1-CG1 3.2Å; I429-V433 PolarHBondContact O-N 2.7Å; A430-V433 PolarHBondContact O-N 2.83Å; L431-V433 VanDerWaalsContact C-N 3.35Å; V433-I435 PolarHBondContact O-N 3.09Å; V433-L436 PolarHBondContact O-N 3.09Å; V433-A437 VanDerWaalsContact O-CB 3.3Å; V433-A437 WeakPolarHBondContact O-CB 3.44Å; V433-A437 PolarHBondContact O-N 3.12Å
434	R	95.1	Very high	92.6	Very high	1 Å²	1	46.9 Å²	46.9	0%	0.004	26%	0.257	C	S	.	.	H	α-helix	trans	-56.8	-47.6	175.2	-164.6	-162.7	-174	64.1	9.6	112	P213 E217 G244 D280 A430 L431 V432 A437 T438 W459	P213-R434 HydrophobicContact CB-CG 3.94Å; E217-R434 HydrophobicContact CB-CB 4.09Å; E217-R434 HydrophobicContact CB-CG 4.28Å; E217-R434 HydrophobicContact CG-CB 4.26Å; E217-R434 WeakPolarHBondContact OE2-CD 3.32Å; E217-R434 IonicContact OE2-CZ 3.96Å; E217-R434 IonicContact OE2-NE 3.14Å; E217-R434 IonicContact OE2-NH1 3.26Å; E217-R434 PolarHBondContact OE2-NH1 3.11Å; G244-R434 PolarHBondContact O-NH1 3.41Å; G244-R434 PolarHBondContact O-NH2 3.39Å; D280-R434 IonicContact OD1-CZ 3.33Å; D280-R434 IonicContact OD1-NH1 3.86Å; D280-R434 IonicContact OD1-NH2 2.73Å; D280-R434 PolarHBondContact OD1-NH2 2.9Å; D280-R434 IonicContact OD2-NH2 2.66Å; D280-R434 PolarHBondContact OD2-NH2 2.85Å; A430-R434 PolarHBondContact O-N 2.89Å; L431-R434 WeakPolarHBondContact O-CB 3.46Å; L431-R434 PolarHBondContact O-N 3.34Å; V432-R434 VanDerWaalsContact C-N 3.34Å; V432-R434 PolarHBondContact O-N 3.48Å; R434-A437 PolarHBondContact O-N 3.06Å; R434-T438 VanDerWaalsContact O-CB 3.32Å; R434-T438 WeakPolarHBondContact O-CB 3.19Å; R434-T438 PolarHBondContact O-N 2.88Å; R434-T438 PolarHBondContact O-OG1 3Å; R434-W459 VanDerWaalsContact CD-O 3.29Å; R434-W459 WeakPolarHBondContact CD-O 3.31Å; R434-W459 PolarHBondContact NE-O 2.99Å
435	I	95	Very high	91.9	Very high	49 Å²	49	44.4 Å²	44.4	25%	0.251	25%	0.249	S	C	.	.	H	α-helix	trans	-61.9	-45.5	-179.8	-69	164.2	0	0	0	110.3	L431 V432 V433 T438 F439 I460	L431-I435 VanDerWaalsContact O-CG1 3.3Å; L431-I435 WeakPolarHBondContact O-CG1 3.41Å; L431-I435 PolarHBondContact O-N 3.36Å; V432-I435 PolarHBondContact O-N 3.17Å; V433-I435 PolarHBondContact O-N 3.09Å; I435-T438 PolarHBondContact O-N 3.4Å; I435-F439 PolarHBondContact O-N 3.36Å; I435-I460 HydrophobicContact CD1-CD1 3.91Å; I435-I460 HydrophobicContact CD1-CG1 3.98Å; I435-I460 HydrophobicContact CG1-CD1 4.49Å; I435-I460 HydrophobicContact CG1-CG1 4.18Å
436	L	95.4	Very high	91.4	Very high	106 Å²	106	45.6 Å²	45.6	56%	0.555	26%	0.264	S	S	*	.	H	α-helix	trans	-64.1	-47.3	177.6	-67.8	171.8	0	0	0	112.1	V432 V433 T438 F439 L440	V432-L436 HydrophobicContact CG1-CD1 4.1Å; V432-L436 WeakPolarHBondContact O-CG 3.48Å; V432-L436 PolarHBondContact O-N 3.45Å; V432-L436 VanDerWaalsContact O-N 3.07Å; V433-L436 PolarHBondContact O-N 3.09Å; L436-T438 VanDerWaalsContact C-N 3.33Å; L436-T438 PolarHBondContact O-N 2.97Å; L436-F439 PolarHBondContact O-N 2.94Å; L436-L440 WeakPolarHBondContact O-CG 3.33Å; L436-L440 PolarHBondContact O-N 3.32Å
437	A	95.1	Very high	91.1	Very high	13 Å²	13	46.5 Å²	46.5	11%	0.107	27%	0.268	C	S	.	.	H	α-helix	trans	-62	-41	177.3	0	0	0	0	0	111.7	S216 V433 R434 L440 M441	S216-A437 WeakPolarHBondContact OG-CB 3.5Å; V433-A437 VanDerWaalsContact O-CB 3.3Å; V433-A437 WeakPolarHBondContact O-CB 3.44Å; V433-A437 PolarHBondContact O-N 3.12Å; R434-A437 PolarHBondContact O-N 3.06Å; A437-L440 PolarHBondContact O-N 3.33Å; A437-M441 WeakPolarHBondContact O-CB 3.47Å; A437-M441 VanDerWaalsContact O-CG 3.25Å; A437-M441 WeakPolarHBondContact O-CG 3.28Å; A437-M441 PolarHBondContact O-N 3.34Å
438	T	93.9	Very high	90.9	Very high	0 Å²	0	49.7 Å²	49.7	0%	0	29%	0.285	C	S	.	.	H	α-helix	trans	-60.5	-47.5	175.3	-54	0	0	0	0	110.9	L209 P213 R434 I435 L436 L440 M441 V442 V455	L209-T438 HydrophobicContact CD1-CG2 3.61Å; P213-T438 WeakPolarHBondContact CB-OG1 3.12Å; P213-T438 HydrophobicContact CG-CG2 4.42Å; P213-T438 VanDerWaalsContact CG-OG1 3.29Å; P213-T438 WeakPolarHBondContact CG-OG1 3.47Å; R434-T438 VanDerWaalsContact O-CB 3.32Å; R434-T438 WeakPolarHBondContact O-CB 3.19Å; R434-T438 PolarHBondContact O-N 2.88Å; R434-T438 PolarHBondContact O-OG1 3Å; I435-T438 PolarHBondContact O-N 3.4Å; L436-T438 VanDerWaalsContact C-N 3.33Å; L436-T438 PolarHBondContact O-N 2.97Å; T438-L440 VanDerWaalsContact C-N 3.35Å; T438-L440 PolarHBondContact O-N 2.86Å; T438-M441 PolarHBondContact O-N 2.84Å; T438-V442 HydrophobicContact CG2-CG2 4.29Å; T438-V442 WeakPolarHBondContact O-CB 3.35Å; T438-V442 WeakPolarHBondContact O-CG2 3.25Å; T438-V442 PolarHBondContact O-N 3.45Å; T438-V442 VanDerWaalsContact O-N 3.08Å; T438-V455 HydrophobicContact CG2-CG1 4.05Å
439	F	93.7	Very high	90.8	Very high	57 Å²	57	55.1 Å²	55.1	25%	0.25	30%	0.3	C	S	.	.	H	α-helix	trans	-57.7	-47.2	177.8	-173.3	-92.7	0	0	0	111.8	I435 L436 V442 C443 F449 K452 V453 S456	I435-F439 PolarHBondContact O-N 3.36Å; L436-F439 PolarHBondContact O-N 2.94Å; F439-V442 PolarHBondContact O-N 3.05Å; F439-C443 PolarHBondContact O-N 3.36Å; F439-C443 VanDerWaalsContact O-N 3.14Å; F439-C443 PolarHBondContact O-SG 3.43Å; F439-F449 HydrophobicContact CE2-CD2 4.29Å; F439-F449 HydrophobicContact CE2-CE2 4.03Å; F439-F449 AromaticContact CZ-CD2 3.97Å; F439-F449 HydrophobicContact CZ-CD2 3.97Å; F439-F449 AromaticContact CZ-CE2 3.65Å; F439-F449 HydrophobicContact CZ-CE2 3.65Å; F439-K452 HydrophobicContact CD2-CB 3.88Å; F439-K452 HydrophobicContact CE2-CB 3.63Å; F439-K452 HydrophobicContact CE2-CD 4.46Å; F439-K452 HydrophobicContact CZ-CB 4.45Å; F439-V453 HydrophobicContact CD2-CG2 4.5Å; F439-V453 HydrophobicContact CE2-CG2 4.09Å; F439-S456 VanDerWaalsContact CA-OG 3.31Å; F439-S456 WeakPolarHBondContact CA-OG 3.49Å; F439-S456 WeakPolarHBondContact CB-OG 3.3Å; F439-S456 PolarHBondContact N-OG 3.3Å
440	L	92.6	Very high	90.6	Very high	109 Å²	109	57.7 Å²	57.7	57%	0.571	31%	0.309	S	S	*	.	H	α-helix	trans	-63.7	-41.7	177.5	-67.8	172.9	0	0	0	112.9	L436 A437 T438 V442 C443	L436-L440 WeakPolarHBondContact O-CG 3.33Å; L436-L440 PolarHBondContact O-N 3.32Å; A437-L440 PolarHBondContact O-N 3.33Å; T438-L440 VanDerWaalsContact C-N 3.35Å; T438-L440 PolarHBondContact O-N 2.86Å; L440-V442 VanDerWaalsContact C-N 3.28Å; L440-V442 PolarHBondContact O-N 2.9Å; L440-C443 WeakPolarHBondContact O-CB 3.32Å; L440-C443 PolarHBondContact O-N 3.47Å
441	M	91.3	Very high	90.4	Very high	64 Å²	64	57.8 Å²	57.8	32%	0.315	31%	0.309	S	S	.	.	H	α-helix	trans	-66.1	-32.2	179.6	-71.9	-59.9	152.1	0	0	112.5	R208 A437 T438	R208-M441 HydrophobicContact CB-SD 4.33Å; R208-M441 PolarHBondContact NE-O 3.32Å; R208-M441 PolarHBondContact NH2-O 3.5Å; A437-M441 WeakPolarHBondContact O-CB 3.47Å; A437-M441 VanDerWaalsContact O-CG 3.25Å; A437-M441 WeakPolarHBondContact O-CG 3.28Å; A437-M441 PolarHBondContact O-N 3.34Å; T438-M441 PolarHBondContact O-N 2.84Å
442	V	88.8	Confident	90.3	Very high	1 Å²	1	58.5 Å²	58.5	1%	0.006	31%	0.311	C	S	.	.	H	α-helix	trans	-86.5	-11.7	-178.8	-177.2	0	0	0	0	112.3	L209 T438 F439 L440 F444 A445 F447 K452 V455	L209-V442 HydrophobicContact CD1-CG2 3.79Å; T438-V442 HydrophobicContact CG2-CG2 4.29Å; T438-V442 WeakPolarHBondContact O-CB 3.35Å; T438-V442 WeakPolarHBondContact O-CG2 3.25Å; T438-V442 PolarHBondContact O-N 3.45Å; T438-V442 VanDerWaalsContact O-N 3.08Å; F439-V442 PolarHBondContact O-N 3.05Å; L440-V442 VanDerWaalsContact C-N 3.28Å; L440-V442 PolarHBondContact O-N 2.9Å; V442-F444 PolarHBondContact O-N 3.04Å; V442-A445 PolarHBondContact O-N 3.29Å; V442-A445 VanDerWaalsContact O-N 3.14Å; V442-F447 HydrophobicContact CG1-CB 4.45Å; V442-F447 HydrophobicContact CG1-CD2 3.4Å; V442-F447 VanDerWaalsContact CG1-CD2 3.4Å; V442-F447 HydrophobicContact CG1-CE2 4.01Å; V442-F447 HydrophobicContact CG1-CG 4.27Å; V442-K452 HydrophobicContact CG1-CG 4.06Å; V442-V455 HydrophobicContact CG1-CG1 4.36Å; V442-V455 HydrophobicContact CG2-CG1 3.67Å
443	C	84.5	Confident	90.2	Very high	40 Å²	40	56.5 Å²	56.5	27%	0.27	30%	0.299	S	S	.	.	T	Hydrogen-bonded Turn	trans	-53.6	-32.6	-177.2	-90.9	0	0	0	0	115.3	F439 L440 K452	F439-C443 PolarHBondContact O-N 3.36Å; F439-C443 VanDerWaalsContact O-N 3.14Å; F439-C443 PolarHBondContact O-SG 3.43Å; L440-C443 WeakPolarHBondContact O-CB 3.32Å; L440-C443 PolarHBondContact O-N 3.47Å; C443-K452 WeakPolarHBondContact O-CE 3.4Å; C443-K452 PolarHBondContact O-NZ 2.88Å
444	F	78.3	Confident	90.1	Very high	169 Å²	169	54.4 Å²	54.4	74%	0.741	29%	0.287	S	S	*	.	T	Hydrogen-bonded Turn	trans	-99.4	9.3	-174.3	-64.1	-93	0	0	0	114.2	V442	V442-F444 PolarHBondContact O-N 3.04Å
445	A	76.9	Confident	90	Very high	26 Å²	26	54.4 Å²	54.4	22%	0.215	29%	0.286	C	S	.	.	T	Hydrogen-bonded Turn	trans	-100.5	17.3	-171.2	0	0	0	0	0	115.1	V205 V442 F447	V205-A445 HydrophobicContact CB-CB 4.32Å; V205-A445 HydrophobicContact CG1-CB 3.54Å; V205-A445 HydrophobicContact CG2-CB 3.74Å; V442-A445 PolarHBondContact O-N 3.29Å; V442-A445 VanDerWaalsContact O-N 3.14Å; A445-F447 VanDerWaalsContact C-N 3.27Å; A445-F447 HydrophobicContact CB-CD2 3.61Å; A445-F447 HydrophobicContact CB-CE2 3.59Å; A445-F447 PolarHBondContact O-N 3.45Å
446	G	81.1	Confident	90	Very high	63 Å²	63	52.2 Å²	52.2	65%	0.649	28%	0.276	S	S	*	.	T	Hydrogen-bonded Turn	trans	76.2	4.8	177.8	0	0	0	0	0	115.9	K267	K267-G446 PolarHBondContact NZ-O 3.17Å
447	F	85.5	Confident	89.9	Confident	19 Å²	19	49.3 Å²	49.3	8%	0.083	26%	0.26	C	S	.	.			trans	-77.8	148.4	177.8	-63.3	-63	0	0	0	113.2	K267 V269 L272 V442 A445 E451 K452	K267-F447 HydrophobicContact CB-CD1 4.32Å; K267-F447 HydrophobicContact CB-CE1 3.94Å; K267-F447 HydrophobicContact CD-CD1 4.13Å; V269-F447 HydrophobicContact CG2-CD1 3.85Å; V269-F447 HydrophobicContact CG2-CE1 3.42Å; V269-F447 VanDerWaalsContact CG2-CE1 3.42Å; V269-F447 HydrophobicContact CG2-CZ 4.24Å; L272-F447 HydrophobicContact CD2-CE2 3.66Å; L272-F447 HydrophobicContact CD2-CZ 3.6Å; V442-F447 HydrophobicContact CG1-CB 4.45Å; V442-F447 HydrophobicContact CG1-CD2 3.4Å; V442-F447 VanDerWaalsContact CG1-CD2 3.4Å; V442-F447 HydrophobicContact CG1-CE2 4.01Å; V442-F447 HydrophobicContact CG1-CG 4.27Å; A445-F447 VanDerWaalsContact C-N 3.27Å; A445-F447 HydrophobicContact CB-CD2 3.61Å; A445-F447 HydrophobicContact CB-CE2 3.59Å; A445-F447 PolarHBondContact O-N 3.45Å; F447-E451 WeakPolarHBondContact CA-OE2 3.42Å; F447-E451 HydrophobicContact CB-CB 3.97Å; F447-E451 HydrophobicContact CD1-CB 4.25Å; F447-E451 HydrophobicContact CG-CB 4.43Å; F447-K452 HydrophobicContact CB-CG 3.95Å; F447-K452 WeakPolarHBondContact O-CE 3.45Å
448	N	90.3	Very high	89.8	Confident	71 Å²	71	48.7 Å²	48.7	38%	0.38	26%	0.255	S	S	.	.			trans	-70.2	159.8	170.9	-62	-22.5	0	0	0	109.9	K267 K450 E451 K452 Q520	K267-N448 PolarHBondContact NZ-ND2 3.39Å; K267-N448 PolarHBondContact NZ-OD1 3.24Å; N448-K450 VanDerWaalsContact C-N 3.29Å; N448-K450 PolarHBondContact O-N 3.34Å; N448-E451 HydrophobicContact CB-CG 4.2Å; N448-E451 WeakPolarHBondContact CB-OE2 3.32Å; N448-E451 PolarHBondContact N-OE2 3.4Å; N448-E451 PolarHBondContact O-N 3.31Å; N448-E451 VanDerWaalsContact O-N 3.08Å; N448-K452 WeakPolarHBondContact O-CG 3.45Å; N448-K452 PolarHBondContact O-N 3.4Å; N448-Q520 PolarHBondContact ND2-OE1 3.13Å
449	F	90.9	Very high	89.7	Confident	147 Å²	147	48.8 Å²	48.8	65%	0.645	26%	0.256	S	S	*	.	H	α-helix	trans	-55.4	-42.6	178.4	-176	-92.8	0	0	0	112.9	F439 E451 K452 V453	F439-F449 HydrophobicContact CE2-CD2 4.29Å; F439-F449 HydrophobicContact CE2-CE2 4.03Å; F439-F449 AromaticContact CZ-CD2 3.97Å; F439-F449 HydrophobicContact CZ-CD2 3.97Å; F439-F449 AromaticContact CZ-CE2 3.65Å; F439-F449 HydrophobicContact CZ-CE2 3.65Å; F449-E451 VanDerWaalsContact C-N 3.35Å; F449-E451 PolarHBondContact O-N 2.92Å; F449-K452 PolarHBondContact O-N 2.87Å; F449-V453 HydrophobicContact CD1-CG2 4.26Å; F449-V453 HydrophobicContact CE1-CG2 3.87Å; F449-V453 HydrophobicContact CZ-CG2 4.15Å; F449-V453 WeakPolarHBondContact O-CG2 3.29Å; F449-V453 PolarHBondContact O-N 3.05Å; F449-V453 VanDerWaalsContact O-N 3.08Å
450	K	91.7	Very high	89.6	Confident	128 Å²	128	46.9 Å²	46.9	56%	0.557	25%	0.248	S	C	*	.	H	α-helix	trans	-59.2	-43.3	176.1	-65.7	-176	178.3	-178.6	0	112.4	N448 V453 F454 L518	N448-K450 VanDerWaalsContact C-N 3.29Å; N448-K450 PolarHBondContact O-N 3.34Å; K450-V453 PolarHBondContact O-N 2.87Å; K450-F454 PolarHBondContact O-N 3.26Å; K450-L518 HydrophobicContact CB-CB 4.17Å; K450-L518 HydrophobicContact CB-CD2 3.97Å; K450-L518 WeakPolarHBondContact CB-O 3.36Å; K450-L518 HydrophobicContact CD-CD2 4.49Å; K450-L518 HydrophobicContact CG-CD2 4.13Å
451	E	91.3	Very high	89.6	Confident	2 Å²	2	41.7 Å²	41.7	1%	0.009	22%	0.221	C	C	.	.	H	α-helix	trans	-69.3	-39.5	179.7	-63.9	168	151.3	0	0	111.6	K267 F447 N448 F449 V453 F454 V455 L519	K267-E451 WeakPolarHBondContact CD-OE1 3.4Å; K267-E451 WeakPolarHBondContact CD-OE2 3.36Å; K267-E451 WeakPolarHBondContact CE-OE1 3.48Å; K267-E451 WeakPolarHBondContact CE-OE2 3.26Å; K267-E451 IonicContact NZ-OE1 2.81Å; K267-E451 IonicContact NZ-OE2 3.78Å; K267-E451 PolarHBondContact NZ-OE2 2.93Å; F447-E451 WeakPolarHBondContact CA-OE2 3.42Å; F447-E451 HydrophobicContact CB-CB 3.97Å; F447-E451 HydrophobicContact CD1-CB 4.25Å; F447-E451 HydrophobicContact CG-CB 4.43Å; N448-E451 HydrophobicContact CB-CG 4.2Å; N448-E451 WeakPolarHBondContact CB-OE2 3.32Å; N448-E451 PolarHBondContact N-OE2 3.4Å; N448-E451 PolarHBondContact O-N 3.31Å; N448-E451 VanDerWaalsContact O-N 3.08Å; F449-E451 VanDerWaalsContact C-N 3.35Å; F449-E451 PolarHBondContact O-N 2.92Å; E451-V453 VanDerWaalsContact C-N 3.34Å; E451-V453 PolarHBondContact O-N 3.29Å; E451-F454 PolarHBondContact O-N 2.99Å; E451-V455 WeakPolarHBondContact O-CG2 3.39Å; E451-V455 PolarHBondContact O-N 2.89Å; E451-L519 HydrophobicContact CG-CD2 4.38Å
452	K	92.8	Very high	89.7	Confident	36 Å²	36	38.7 Å²	38.7	16%	0.157	21%	0.206	C	C	.	.	H	α-helix	trans	-58.8	-44.3	173.3	-69.2	173.5	176.8	176.9	0	111.8	F439 V442 C443 F447 N448 F449 S456	F439-K452 HydrophobicContact CD2-CB 3.88Å; F439-K452 HydrophobicContact CE2-CB 3.63Å; F439-K452 HydrophobicContact CE2-CD 4.46Å; F439-K452 HydrophobicContact CZ-CB 4.45Å; V442-K452 HydrophobicContact CG1-CG 4.06Å; C443-K452 WeakPolarHBondContact O-CE 3.4Å; C443-K452 PolarHBondContact O-NZ 2.88Å; F447-K452 HydrophobicContact CB-CG 3.95Å; F447-K452 WeakPolarHBondContact O-CE 3.45Å; N448-K452 WeakPolarHBondContact O-CG 3.45Å; N448-K452 PolarHBondContact O-N 3.4Å; F449-K452 PolarHBondContact O-N 2.87Å; K452-S456 PolarHBondContact O-N 3.48Å; K452-S456 VanDerWaalsContact O-N 3.12Å; K452-S456 PolarHBondContact O-OG 3.25Å
453	V	94.1	Very high	89.7	Confident	42 Å²	42	38.7 Å²	38.7	26%	0.255	21%	0.206	S	C	.	.	H	α-helix	trans	-63.8	-45.5	174.6	173.2	0	0	0	0	110.6	F439 F449 K450 E451 V455 S456 L457 L518	F439-V453 HydrophobicContact CD2-CG2 4.5Å; F439-V453 HydrophobicContact CE2-CG2 4.09Å; F449-V453 HydrophobicContact CD1-CG2 4.26Å; F449-V453 HydrophobicContact CE1-CG2 3.87Å; F449-V453 HydrophobicContact CZ-CG2 4.15Å; F449-V453 WeakPolarHBondContact O-CG2 3.29Å; F449-V453 PolarHBondContact O-N 3.05Å; F449-V453 VanDerWaalsContact O-N 3.08Å; K450-V453 PolarHBondContact O-N 2.87Å; E451-V453 VanDerWaalsContact C-N 3.34Å; E451-V453 PolarHBondContact O-N 3.29Å; V453-V455 PolarHBondContact O-N 2.95Å; V453-S456 PolarHBondContact O-N 3.43Å; V453-L457 HydrophobicContact CG1-CD1 3.76Å; V453-L457 HydrophobicContact CG1-CG 4.26Å; V453-L457 WeakPolarHBondContact O-CB 3.23Å; V453-L457 VanDerWaalsContact O-CG 3.3Å; V453-L457 WeakPolarHBondContact O-CG 3.45Å; V453-L457 PolarHBondContact O-N 3.42Å; V453-L518 HydrophobicContact CB-CD1 4.33Å; V453-L518 HydrophobicContact CG1-CD1 3.96Å
454	F	94.9	Very high	89.7	Confident	0 Å²	0	37 Å²	37	0%	0	19%	0.194	C	C	.	.	H	α-helix	trans	-58.4	-48	176.8	177.2	-98	0	0	0	112.8	M255 L258 V269 L273 K450 E451 S456 L457 A458 I511 A514 L518 L519	M255-F454 HydrophobicContact CE-CE1 4.05Å; M255-F454 HydrophobicContact CE-CZ 3.76Å; M255-F454 HydrophobicContact SD-CE1 4.18Å; M255-F454 HydrophobicContact SD-CZ 4.16Å; L258-F454 HydrophobicContact CD1-CE1 4.5Å; L258-F454 HydrophobicContact CD1-CE2 4.09Å; L258-F454 HydrophobicContact CD1-CZ 3.53Å; V269-F454 HydrophobicContact CG1-CD1 3.91Å; V269-F454 HydrophobicContact CG1-CE1 4.05Å; L273-F454 HydrophobicContact CD1-CD1 4.22Å; L273-F454 HydrophobicContact CD1-CE1 3.63Å; K450-F454 PolarHBondContact O-N 3.26Å; E451-F454 PolarHBondContact O-N 2.99Å; F454-S456 VanDerWaalsContact C-N 3.3Å; F454-S456 PolarHBondContact O-N 3.43Å; F454-L457 PolarHBondContact O-N 3.24Å; F454-A458 HydrophobicContact CE1-CB 4.37Å; F454-A458 HydrophobicContact CZ-CB 4.42Å; F454-A458 WeakPolarHBondContact O-CB 3.21Å; F454-A458 PolarHBondContact O-N 3.4Å; F454-I511 HydrophobicContact CE2-CG2 4.3Å; F454-I511 HydrophobicContact CZ-CG2 4.22Å; F454-A514 HydrophobicContact CD2-CB 4.03Å; F454-A514 HydrophobicContact CE2-CB 4.5Å; F454-L518 HydrophobicContact CB-CB 4Å; F454-L518 HydrophobicContact CB-CD1 3.96Å; F454-L519 HydrophobicContact CB-CD2 4.38Å; F454-L519 HydrophobicContact CD1-CD1 4.1Å; F454-L519 HydrophobicContact CD1-CD2 3.61Å; F454-L519 HydrophobicContact CD1-CG 4Å; F454-L519 HydrophobicContact CD2-CG 4.45Å; F454-L519 HydrophobicContact CE1-CD1 3.76Å; F454-L519 HydrophobicContact CE1-CD2 4.09Å; F454-L519 HydrophobicContact CE1-CG 4.18Å; F454-L519 HydrophobicContact CE2-CD1 4.39Å; F454-L519 HydrophobicContact CG-CD2 4Å; F454-L519 HydrophobicContact CG-CG 4.12Å; F454-L519 HydrophobicContact CZ-CD1 3.92Å; F454-L519 HydrophobicContact CZ-CG 4.5Å
455	V	93.1	Very high	90.1	Very high	0 Å²	0	29.3 Å²	29.3	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-59.5	-42.3	178.7	169.8	0	0	0	0	111.2	L209 V269 L273 T438 V442 E451 V453 A458	L209-V455 HydrophobicContact CD1-CG1 4.02Å; L209-V455 HydrophobicContact CD2-CG1 4.17Å; V269-V455 HydrophobicContact CG1-CG2 3.7Å; L273-V455 HydrophobicContact CD1-CG2 4.4Å; L273-V455 HydrophobicContact CD2-CB 4.38Å; L273-V455 HydrophobicContact CD2-CG1 3.9Å; L273-V455 HydrophobicContact CD2-CG2 4.37Å; L273-V455 HydrophobicContact CG-CG2 4.48Å; T438-V455 HydrophobicContact CG2-CG1 4.05Å; V442-V455 HydrophobicContact CG1-CG1 4.36Å; V442-V455 HydrophobicContact CG2-CG1 3.67Å; E451-V455 WeakPolarHBondContact O-CG2 3.39Å; E451-V455 PolarHBondContact O-N 2.89Å; V453-V455 PolarHBondContact O-N 2.95Å; V455-A458 PolarHBondContact O-N 3.27Å
456	S	94.3	Very high	90.8	Very high	3 Å²	3	28.1 Å²	28.1	2%	0.021	15%	0.151	C	C	.	.	H	α-helix	trans	-65.7	-38.8	178	-50.9	0	0	0	0	112.9	F439 K452 V453 F454	F439-S456 VanDerWaalsContact CA-OG 3.31Å; F439-S456 WeakPolarHBondContact CA-OG 3.49Å; F439-S456 WeakPolarHBondContact CB-OG 3.3Å; F439-S456 PolarHBondContact N-OG 3.3Å; K452-S456 PolarHBondContact O-N 3.48Å; K452-S456 VanDerWaalsContact O-N 3.12Å; K452-S456 PolarHBondContact O-OG 3.25Å; V453-S456 PolarHBondContact O-N 3.43Å; F454-S456 VanDerWaalsContact C-N 3.3Å; F454-S456 PolarHBondContact O-N 3.43Å
457	L	93.9	Very high	91.1	Very high	45 Å²	45	25.1 Å²	25.1	24%	0.236	12%	0.12	C	C	.	.	H	α-helix	trans	-75.6	-31.5	178.2	-71.6	179.5	0	0	0	113.1	V453 F454 W459 I460 V510	V453-L457 HydrophobicContact CG1-CD1 3.76Å; V453-L457 HydrophobicContact CG1-CG 4.26Å; V453-L457 WeakPolarHBondContact O-CB 3.23Å; V453-L457 VanDerWaalsContact O-CG 3.3Å; V453-L457 WeakPolarHBondContact O-CG 3.45Å; V453-L457 PolarHBondContact O-N 3.42Å; F454-L457 PolarHBondContact O-N 3.24Å; L457-W459 PolarHBondContact O-N 2.96Å; L457-I460 HydrophobicContact CD2-CD1 3.85Å; L457-I460 WeakPolarHBondContact O-CD1 3.33Å; L457-I460 WeakPolarHBondContact O-CG1 3.23Å; L457-I460 PolarHBondContact O-N 2.94Å; L457-V510 HydrophobicContact CB-CG1 3.66Å; L457-V510 HydrophobicContact CD1-CG1 4.11Å; L457-V510 HydrophobicContact CD2-CG1 4.29Å; L457-V510 HydrophobicContact CG-CG1 4.23Å
458	A	92.3	Very high	90.9	Very high	0 Å²	0	24.4 Å²	24.4	0%	0	12%	0.118	C	C	.	.	T	Hydrogen-bonded Turn	trans	-66.6	-13.5	175.9	0	0	0	0	0	113.6	V251 M255 L273 F454 V455 P461 I511	V251-A458 WeakPolarHBondContact CG2-O 3.31Å; M255-A458 HydrophobicContact CE-CB 3.7Å; L273-A458 HydrophobicContact CD1-CB 4.01Å; L273-A458 HydrophobicContact CD2-CB 4.1Å; F454-A458 HydrophobicContact CE1-CB 4.37Å; F454-A458 HydrophobicContact CZ-CB 4.42Å; F454-A458 WeakPolarHBondContact O-CB 3.21Å; F454-A458 PolarHBondContact O-N 3.4Å; V455-A458 PolarHBondContact O-N 3.27Å; A458-P461 VanDerWaalsContact O-CD 3.26Å; A458-P461 WeakPolarHBondContact O-CD 3.39Å; A458-I511 HydrophobicContact CB-CD1 4.39Å; A458-I511 HydrophobicContact CB-CG1 4.07Å
459	W	90.8	Very high	90.8	Very high	2 Å²	2	21.1 Å²	21.1	1%	0.008	10%	0.101	C	C	.	.	T	Hydrogen-bonded Turn	trans	-97.4	8	-177.5	-86.3	41	0	0	0	114.2	L209 P213 V246 A276 D280 R434 L457	L209-W459 HydrophobicContact CD1-CD2 4.27Å; L209-W459 HydrophobicContact CD1-CE3 4.3Å; L209-W459 HydrophobicContact CD1-CH2 4.35Å; L209-W459 HydrophobicContact CD1-CZ2 4.24Å; L209-W459 HydrophobicContact CD1-CZ3 4.36Å; L209-W459 HydrophobicContact CD2-CZ2 4.34Å; L209-W459 HydrophobicContact CG-CH2 4.04Å; L209-W459 HydrophobicContact CG-CZ2 3.87Å; L209-W459 HydrophobicContact CG-CZ3 4.5Å; L209-W459 WeakPolarHBondContact O-CH2 3.35Å; L209-W459 WeakPolarHBondContact O-CZ3 3.47Å; P213-W459 HydrophobicContact CB-CE3 3.88Å; P213-W459 HydrophobicContact CB-CZ3 3.99Å; P213-W459 HydrophobicContact CG-CE3 4.03Å; P213-W459 HydrophobicContact CG-CZ3 4.02Å; V246-W459 HydrophobicContact CG2-CD2 3.9Å; V246-W459 HydrophobicContact CG2-CE3 4Å; V246-W459 HydrophobicContact CG2-CG 4.24Å; V246-W459 HydrophobicContact CG2-CH2 4.46Å; V246-W459 HydrophobicContact CG2-CZ2 4.45Å; V246-W459 HydrophobicContact CG2-CZ3 4.26Å; A276-W459 HydrophobicContact CB-CH2 4.14Å; A276-W459 HydrophobicContact CB-CZ2 3.69Å; D280-W459 HydrophobicContact CB-CH2 3.75Å; D280-W459 HydrophobicContact CB-CZ3 4.2Å; D280-W459 VanDerWaalsContact OD1-CZ3 3.24Å; D280-W459 WeakPolarHBondContact OD1-CZ3 3.38Å; R434-W459 VanDerWaalsContact CD-O 3.29Å; R434-W459 WeakPolarHBondContact CD-O 3.31Å; R434-W459 PolarHBondContact NE-O 2.99Å; L457-W459 PolarHBondContact O-N 2.96Å
460	I	93.2	Very high	90.6	Very high	18 Å²	18	14.1 Å²	14.1	9%	0.092	7%	0.07	C	C	.	.			trans	-71.4	-41.5	173.1	-65.3	171.6	0	0	0	114.7	L431 I435 L457 K462	L431-I460 HydrophobicContact CD2-CG2 4.48Å; I435-I460 HydrophobicContact CD1-CD1 3.91Å; I435-I460 HydrophobicContact CD1-CG1 3.98Å; I435-I460 HydrophobicContact CG1-CD1 4.49Å; I435-I460 HydrophobicContact CG1-CG1 4.18Å; L457-I460 HydrophobicContact CD2-CD1 3.85Å; L457-I460 WeakPolarHBondContact O-CD1 3.33Å; L457-I460 WeakPolarHBondContact O-CG1 3.23Å; L457-I460 PolarHBondContact O-N 2.94Å; I460-K462 PolarHBondContact O-N 3.17Å
461	P	92.2	Very high	90.4	Very high	0 Å²	0	8.1 Å²	8.1	0%	0	4%	0.044	C	C	.	.			trans	-71.1	125.4	-166	1.4	5.1	0	0	0	114.2	S247 V250 V251 A458 I511	S247-P461 PolarHBondContact N-O 2.74Å; V250-P461 HydrophobicContact CB-CB 3.91Å; V250-P461 HydrophobicContact CB-CG 4.44Å; V250-P461 HydrophobicContact CG1-CB 3.76Å; V250-P461 HydrophobicContact CG1-CG 4.06Å; V250-P461 HydrophobicContact CG2-CB 4.44Å; V251-P461 HydrophobicContact CG2-CG 3.86Å; A458-P461 VanDerWaalsContact O-CD 3.26Å; A458-P461 WeakPolarHBondContact O-CD 3.39Å; P461-I511 HydrophobicContact CG-CD1 3.85Å
462	K	92.1	Very high	90.2	Very high	1 Å²	1	8.4 Å²	8.4	0%	0.004	5%	0.045	C	C	.	.			trans	-112.9	138	172.5	-60.1	170.1	149	62.3	0	109.5	E217 L243 L427 I460 Q466 A499 T503 A504	E217-K462 IonicContact OE1-NZ 3.49Å; E217-K462 PolarHBondContact OE1-NZ 2.95Å; E217-K462 IonicContact OE2-NZ 3.66Å; E217-K462 PolarHBondContact OE2-NZ 3.22Å; L243-K462 HydrophobicContact CD2-CD 4.22Å; L243-K462 WeakPolarHBondContact O-CE 3.48Å; L243-K462 PolarHBondContact O-NZ 2.85Å; L427-K462 HydrophobicContact CD1-CD 4.09Å; I460-K462 PolarHBondContact O-N 3.17Å; K462-Q466 HydrophobicContact CB-CG 4.05Å; K462-A499 HydrophobicContact CB-CB 4.42Å; K462-A499 HydrophobicContact CD-CB 3.96Å; K462-T503 WeakPolarHBondContact CA-OG1 3.33Å; K462-T503 WeakPolarHBondContact CB-OG1 3.45Å; K462-T503 HydrophobicContact CD-CG2 4.38Å; K462-T503 PolarHBondContact N-OG1 3.05Å; K462-T503 PolarHBondContact O-OG1 3.46Å; K462-A504 WeakPolarHBondContact O-CB 3.41Å
463	A	89	Confident	90	Very high	0 Å²	0	6.7 Å²	6.7	0%	0	4%	0.038	C	C	.	.			trans	-165.5	-80.3	-176.7	0	0	0	0	0	112.7	L148 S247 V250 A467 I500 A504	L148-A463 HydrophobicContact CD1-CB 4.12Å; S247-A463 VanDerWaalsContact CB-N 3.27Å; S247-A463 WeakPolarHBondContact OG-CB 3.35Å; V250-A463 HydrophobicContact CG2-CB 4.08Å; A463-A467 WeakPolarHBondContact O-CB 3.46Å; A463-A467 PolarHBondContact O-N 3.32Å; A463-A467 VanDerWaalsContact O-N 3.09Å; A463-I500 HydrophobicContact CB-CG2 4.39Å; A463-A504 HydrophobicContact CB-CB 4.26Å
464	T	84.3	Confident	89.7	Confident	5 Å²	5	4.7 Å²	4.7	3%	0.031	3%	0.026	C	C	.	.	H	α-helix	trans	-75.7	-40.3	-164.7	40.3	0	0	0	0	114.8	L148 S247 A249 W395 F403 A467 A468	L148-T464 HydrophobicContact CD1-CG2 3.95Å; S247-T464 PolarHBondContact OG-N 3.42Å; S247-T464 VanDerWaalsContact OG-N 3.11Å; S247-T464 PolarHBondContact OG-OG1 2.96Å; A249-T464 HydrophobicContact CB-CG2 3.49Å; A249-T464 VanDerWaalsContact CB-CG2 3.49Å; W395-T464 HydrophobicContact CZ2-CG2 4.36Å; F403-T464 HydrophobicContact CE2-CG2 4.22Å; F403-T464 HydrophobicContact CZ-CG2 3.86Å; T464-A467 PolarHBondContact O-N 2.92Å; T464-A468 WeakPolarHBondContact O-CB 3.39Å; T464-A468 PolarHBondContact O-N 3.49Å
465	V	86.8	Confident	89.3	Confident	8 Å²	8	5.5 Å²	5.5	5%	0.048	3%	0.03	C	C	.	.	H	α-helix	trans	-68.4	-45.2	178.5	-177.8	0	0	0	0	109.7	A245 D281 I285 A467 A468 I469	A245-V465 HydrophobicContact CB-CB 3.59Å; A245-V465 HydrophobicContact CB-CG1 3.46Å; A245-V465 VanDerWaalsContact CB-CG1 3.46Å; A245-V465 HydrophobicContact CB-CG2 3.99Å; D281-V465 HydrophobicContact CB-CG2 4.39Å; I285-V465 HydrophobicContact CD1-CG1 4.36Å; I285-V465 HydrophobicContact CG1-CG1 3.94Å; V465-A467 VanDerWaalsContact C-N 3.28Å; V465-A467 PolarHBondContact O-N 2.89Å; V465-A468 PolarHBondContact O-N 3.48Å; V465-I469 HydrophobicContact CG1-CD1 3.85Å; V465-I469 HydrophobicContact CG1-CG1 3.85Å; V465-I469 WeakPolarHBondContact O-CG1 3.26Å; V465-I469 PolarHBondContact O-N 3.38Å
466	Q	92.3	Very high	89	Confident	0 Å²	0	5.7 Å²	5.7	0%	0	3%	0.032	C	C	.	.	H	α-helix	trans	-54.9	-44.1	175.4	-70.1	71.1	29.7	0	0	112.2	V242 A245 K462 G470 A496 I500	V242-Q466 HydrophobicContact CG1-CB 4.38Å; V242-Q466 HydrophobicContact CG1-CG 4.17Å; V242-Q466 WeakPolarHBondContact O-CG 3.47Å; V242-Q466 PolarHBondContact O-NE2 3.44Å; A245-Q466 PolarHBondContact O-NE2 3.26Å; K462-Q466 HydrophobicContact CB-CG 4.05Å; Q466-G470 VanDerWaalsContact O-CA 3.26Å; Q466-G470 WeakPolarHBondContact O-CA 3.41Å; Q466-G470 PolarHBondContact O-N 3.45Å; Q466-A496 HydrophobicContact CB-CB 4.33Å; Q466-I500 HydrophobicContact CB-CD1 4.04Å; Q466-I500 HydrophobicContact CB-CG1 3.84Å
467	A	86.6	Confident	88.7	Confident	0 Å²	0	5.6 Å²	5.6	0%	0	3%	0.031	C	C	.	.	H	α-helix	trans	-63.8	-47.5	175.9	0	0	0	0	0	111.5	L402 F403 I406 A463 T464 V465 I500	L402-A467 HydrophobicContact CD2-CB 3.97Å; L402-A467 HydrophobicContact CG-CB 4.27Å; F403-A467 HydrophobicContact CD1-CB 4.15Å; F403-A467 HydrophobicContact CE1-CB 3.58Å; F403-A467 HydrophobicContact CE2-CB 4.28Å; F403-A467 HydrophobicContact CZ-CB 3.66Å; I406-A467 HydrophobicContact CD1-CB 3.59Å; I406-A467 WeakPolarHBondContact CD1-O 3.37Å; A463-A467 WeakPolarHBondContact O-CB 3.46Å; A463-A467 PolarHBondContact O-N 3.32Å; A463-A467 VanDerWaalsContact O-N 3.09Å; T464-A467 PolarHBondContact O-N 2.92Å; V465-A467 VanDerWaalsContact C-N 3.28Å; V465-A467 PolarHBondContact O-N 2.89Å; A467-I500 HydrophobicContact CB-CD1 4Å
468	A	82.8	Confident	88.3	Confident	5 Å²	5	5.6 Å²	5.6	4%	0.041	3%	0.028	C	C	.	.	H	α-helix	trans	-66.7	-52.5	-174.6	0	0	0	0	0	113.2	L183 I186 L402 T464 V465	L183-A468 HydrophobicContact CD1-CB 3.75Å; I186-A468 HydrophobicContact CG2-CB 3.84Å; L402-A468 HydrophobicContact CD2-CB 4.34Å; T464-A468 WeakPolarHBondContact O-CB 3.39Å; T464-A468 PolarHBondContact O-N 3.49Å; V465-A468 PolarHBondContact O-N 3.48Å
469	I	87.4	Confident	87.8	Confident	2 Å²	2	9.1 Å²	9.1	1%	0.01	5%	0.052	C	C	.	.	H	α-helix	trans	-92	-22.5	-175.8	53.4	158	0	0	0	114	L183 V242 F288 V465 S471 L472	L183-I469 HydrophobicContact CD1-CG2 4.07Å; V242-I469 HydrophobicContact CG2-CD1 4Å; V242-I469 HydrophobicContact CG2-CG1 4.26Å; F288-I469 HydrophobicContact CB-CD1 3.7Å; F288-I469 HydrophobicContact CD1-CB 3.87Å; F288-I469 HydrophobicContact CD1-CD1 4.11Å; F288-I469 HydrophobicContact CD1-CG2 4Å; F288-I469 HydrophobicContact CD2-CB 4.3Å; F288-I469 HydrophobicContact CD2-CD1 3.76Å; F288-I469 HydrophobicContact CD2-CG1 4.45Å; F288-I469 HydrophobicContact CE1-CB 3.81Å; F288-I469 HydrophobicContact CE1-CG2 4.12Å; F288-I469 HydrophobicContact CE2-CB 4.17Å; F288-I469 HydrophobicContact CE2-CD1 4.39Å; F288-I469 WeakPolarHBondContact CE2-O 3.28Å; F288-I469 HydrophobicContact CG-CB 4.14Å; F288-I469 HydrophobicContact CG-CD1 3.57Å; F288-I469 HydrophobicContact CG-CG1 4.41Å; F288-I469 HydrophobicContact CZ-CB 3.96Å; F288-I469 WeakPolarHBondContact CZ-O 3.49Å; V465-I469 HydrophobicContact CG1-CD1 3.85Å; V465-I469 HydrophobicContact CG1-CG1 3.85Å; V465-I469 WeakPolarHBondContact O-CG1 3.26Å; V465-I469 PolarHBondContact O-N 3.38Å; I469-S471 VanDerWaalsContact C-N 3.27Å; I469-S471 PolarHBondContact O-N 3.27Å; I469-L472 WeakPolarHBondContact O-CB 3.36Å; I469-L472 PolarHBondContact O-N 3.34Å
470	G	87.7	Confident	87.3	Confident	0 Å²	0	13.8 Å²	13.8	0%	0	7%	0.074	C	C	.	.	H	α-helix	trans	-62.1	-30.7	-177.8	0	0	0	0	0	114.2	Q466	Q466-G470 VanDerWaalsContact O-CA 3.26Å; Q466-G470 WeakPolarHBondContact O-CA 3.41Å; Q466-G470 PolarHBondContact O-N 3.45Å
471	S	86.5	Confident	86.7	Confident	2 Å²	2	21.7 Å²	21.7	1%	0.014	11%	0.11	C	C	.	.	T	Hydrogen-bonded Turn	trans	-83.5	-21.9	174.1	54.6	0	0	0	0	114	R179 I469 A473 L474 D475	R179-S471 WeakPolarHBondContact CD-OG 3.37Å; I469-S471 VanDerWaalsContact C-N 3.27Å; I469-S471 PolarHBondContact O-N 3.27Å; S471-A473 VanDerWaalsContact C-N 3.3Å; S471-A473 PolarHBondContact O-N 3.31Å; S471-L474 WeakPolarHBondContact O-CB 3.37Å; S471-L474 PolarHBondContact O-N 2.93Å; S471-D475 PolarHBondContact O-N 3.46Å
472	L	86.9	Confident	86.2	Confident	7 Å²	7	24.9 Å²	24.9	4%	0.037	13%	0.128	C	C	.	.	H	α-helix	trans	-66.2	-33.4	-174.4	179.4	56.1	0	0	0	112	L183 F288 L292 I469 T476	L183-L472 HydrophobicContact CD2-CD2 3.96Å; F288-L472 HydrophobicContact CE1-CB 4.27Å; F288-L472 HydrophobicContact CE1-CD2 4Å; F288-L472 HydrophobicContact CE1-CG 4.31Å; F288-L472 HydrophobicContact CZ-CB 4.18Å; L292-L472 HydrophobicContact CD2-CD2 4.28Å; L292-L472 HydrophobicContact CD2-CG 4.05Å; I469-L472 WeakPolarHBondContact O-CB 3.36Å; I469-L472 PolarHBondContact O-N 3.34Å; L472-T476 VanDerWaalsContact O-CB 3.32Å; L472-T476 WeakPolarHBondContact O-CB 3.49Å; L472-T476 PolarHBondContact O-N 3.49Å; L472-T476 PolarHBondContact O-OG1 3.37Å
473	A	88.6	Confident	86	Confident	0 Å²	0	32.6 Å²	32.6	0%	0	16%	0.164	C	C	.	.	H	α-helix	trans	-66.8	-40.1	175.4	0	0	0	0	0	112.3	W235 I238 F288 L292 S471 A477	W235-A473 HydrophobicContact CH2-CB 4.18Å; W235-A473 HydrophobicContact CZ3-CB 3.74Å; I238-A473 HydrophobicContact CG2-CB 3.97Å; F288-A473 HydrophobicContact CE2-CB 4.31Å; F288-A473 HydrophobicContact CZ-CB 4.15Å; L292-A473 HydrophobicContact CD1-CB 4Å; S471-A473 VanDerWaalsContact C-N 3.3Å; S471-A473 PolarHBondContact O-N 3.31Å; A473-A477 WeakPolarHBondContact O-CB 3.2Å; A473-A477 PolarHBondContact O-N 3.31Å
474	L	89	Confident	86	Confident	0 Å²	0	37.6 Å²	37.6	0%	0	19%	0.187	C	C	.	.	H	α-helix	trans	-66.8	-46	173.9	174.5	63.9	0	0	0	112.1	S471 T476 A477 R478 E486 M490 L493	S471-L474 WeakPolarHBondContact O-CB 3.37Å; S471-L474 PolarHBondContact O-N 2.93Å; L474-T476 VanDerWaalsContact C-N 3.29Å; L474-T476 PolarHBondContact O-N 3.03Å; L474-A477 WeakPolarHBondContact O-CB 3.38Å; L474-A477 PolarHBondContact O-N 3.36Å; L474-A477 VanDerWaalsContact O-N 3.17Å; L474-R478 HydrophobicContact CD1-CG 4.39Å; L474-R478 WeakPolarHBondContact O-CG 3.39Å; L474-R478 PolarHBondContact O-N 2.89Å; L474-E486 HydrophobicContact CD1-CG 3.81Å; L474-M490 HydrophobicContact CD1-CG 3.84Å; L474-M490 HydrophobicContact CD1-SD 3.81Å; L474-M490 HydrophobicContact CD2-SD 3.47Å; L474-M490 WeakPolarHBondContact CD2-SD 3.34Å; L474-M490 HydrophobicContact CG-SD 4.3Å; L474-L493 HydrophobicContact CD2-CD2 3.48Å; L474-L493 VanDerWaalsContact CD2-CD2 3.48Å
475	D	86.1	Confident	86.2	Confident	17 Å²	17	38.9 Å²	38.9	9%	0.091	19%	0.193	C	C	.	.	H	α-helix	trans	-65.5	-34.5	179.9	-72	-28.7	0	0	0	111.4	A176 R179 S471 R478 S479	A176-D475 HydrophobicContact CB-CB 4.21Å; R179-D475 IonicContact CZ-OD1 2.88Å; R179-D475 IonicContact CZ-OD2 3.42Å; R179-D475 IonicContact NE-OD2 3.25Å; R179-D475 PolarHBondContact NE-OD2 2.99Å; R179-D475 VanDerWaalsContact NH2-CG 3.31Å; R179-D475 IonicContact NH2-OD1 3.05Å; R179-D475 PolarHBondContact NH2-OD1 3.17Å; R179-D475 IonicContact NH2-OD2 2.87Å; R179-D475 PolarHBondContact NH2-OD2 2.97Å; R179-D475 VanDerWaalsContact NH2-OD2 3.11Å; S471-D475 PolarHBondContact O-N 3.46Å; D475-R478 IonicContact OD1-NH1 2.74Å; D475-S479 PolarHBondContact O-N 2.84Å
476	T	85.6	Confident	86.4	Confident	5 Å²	5	41.5 Å²	41.5	3%	0.031	21%	0.205	C	C	.	.	H	α-helix	trans	-70.1	-38.2	171.6	-52.1	0	0	0	0	111.9	F296 P362 L472 L474 S479 H480	F296-T476 HydrophobicContact CD1-CG2 4.08Å; F296-T476 HydrophobicContact CD2-CG2 3.62Å; F296-T476 HydrophobicContact CE1-CG2 4.1Å; F296-T476 HydrophobicContact CE2-CG2 3.66Å; F296-T476 HydrophobicContact CG-CG2 3.85Å; F296-T476 HydrophobicContact CZ-CG2 3.9Å; P362-T476 HydrophobicContact CB-CG2 4.31Å; P362-T476 HydrophobicContact CG-CG2 4.13Å; L472-T476 VanDerWaalsContact O-CB 3.32Å; L472-T476 WeakPolarHBondContact O-CB 3.49Å; L472-T476 PolarHBondContact O-N 3.49Å; L472-T476 PolarHBondContact O-OG1 3.37Å; L474-T476 VanDerWaalsContact C-N 3.29Å; L474-T476 PolarHBondContact O-N 3.03Å; T476-S479 PolarHBondContact O-N 3.31Å; T476-S479 PolarHBondContact O-OG 3.43Å; T476-H480 PolarHBondContact O-N 2.8Å; T476-H480 PolarHBondContact O-ND1 3.34Å
477	A	87.7	Confident	86.2	Confident	0 Å²	0	46.6 Å²	46.6	0%	0	23%	0.227	C	C	.	.	H	α-helix	trans	-61.6	-47.8	174.4	0	0	0	0	0	112	W235 F296 A473 L474 S479 H480 Q481 L485	W235-A477 HydrophobicContact CH2-CB 4.39Å; F296-A477 HydrophobicContact CE1-CB 4.38Å; F296-A477 HydrophobicContact CZ-CB 3.95Å; A473-A477 WeakPolarHBondContact O-CB 3.2Å; A473-A477 PolarHBondContact O-N 3.31Å; L474-A477 WeakPolarHBondContact O-CB 3.38Å; L474-A477 PolarHBondContact O-N 3.36Å; L474-A477 VanDerWaalsContact O-N 3.17Å; A477-S479 VanDerWaalsContact C-N 3.29Å; A477-S479 PolarHBondContact O-N 3.43Å; A477-H480 PolarHBondContact O-N 3.43Å; A477-Q481 PolarHBondContact O-N 3.03Å; A477-L485 VanDerWaalsContact CB-C 3.42Å; A477-L485 HydrophobicContact CB-CB 3.8Å; A477-L485 WeakPolarHBondContact CB-O 3.24Å
478	R	85.7	Confident	86.5	Confident	46 Å²	46	49 Å²	49	17%	0.174	24%	0.236	C	C	.	.	H	α-helix	trans	-59.4	-35.8	177.4	-74.4	169.8	170.3	167.5	-2.1	112.9	E409 L474 D475 H480 Q481 E486	E409-R478 VanDerWaalsContact CD-NH1 3.29Å; E409-R478 IonicContact OE1-NH1 3.5Å; E409-R478 PolarHBondContact OE1-NH1 3.44Å; E409-R478 IonicContact OE2-CZ 2.71Å; E409-R478 IonicContact OE2-NH1 3.77Å; E409-R478 PolarHBondContact OE2-NH1 3.47Å; E409-R478 IonicContact OE2-NH2 3.91Å; E409-R478 PolarHBondContact OE2-NH2 3.22Å; L474-R478 HydrophobicContact CD1-CG 4.39Å; L474-R478 WeakPolarHBondContact O-CG 3.39Å; L474-R478 PolarHBondContact O-N 2.89Å; D475-R478 IonicContact OD1-NH1 2.74Å; R478-H480 VanDerWaalsContact C-N 3.26Å; R478-H480 PolarHBondContact O-N 3.04Å; R478-Q481 PolarHBondContact O-N 3.22Å; R478-E486 HydrophobicContact CG-CG 4.27Å; R478-E486 IonicContact CZ-OE1 3.62Å; R478-E486 IonicContact NE-OE1 3.42Å; R478-E486 PolarHBondContact NE-OE1 3.06Å; R478-E486 IonicContact NH2-OE1 2.7Å; R478-E486 PolarHBondContact NH2-OE1 2.91Å
479	S	82.4	Confident	86.9	Confident	73 Å²	73	48.7 Å²	48.7	51%	0.51	24%	0.235	S	C	.	.	H	α-helix	trans	-69.3	-23.4	176.9	74	0	0	0	0	113.6	D475 T476 A477	D475-S479 PolarHBondContact O-N 2.84Å; T476-S479 PolarHBondContact O-N 3.31Å; T476-S479 PolarHBondContact O-OG 3.43Å; A477-S479 VanDerWaalsContact C-N 3.29Å; A477-S479 PolarHBondContact O-N 3.43Å
480	H	81.3	Confident	87	Confident	100 Å²	100	50.8 Å²	50.8	46%	0.463	25%	0.245	S	C	.	.	H	α-helix	trans	-90.4	-5.7	175.6	-68.4	81.7	0	0	0	113.4	F296 T476 A477 R478 D482	F296-H480 AromaticContact CD1-CE1 3.58Å; F296-H480 AromaticContact CD1-CG 3.83Å; F296-H480 AromaticContact CD1-ND1 3.48Å; F296-H480 WeakPolarHBondContact CD1-ND1 3.46Å; F296-H480 AromaticContact CD1-NE2 3.97Å; F296-H480 HydrophobicContact CE1-CB 4.42Å; F296-H480 AromaticContact CE1-ND1 3.72Å; T476-H480 PolarHBondContact O-N 2.8Å; T476-H480 PolarHBondContact O-ND1 3.34Å; A477-H480 PolarHBondContact O-N 3.43Å; R478-H480 VanDerWaalsContact C-N 3.26Å; R478-H480 PolarHBondContact O-N 3.04Å; H480-D482 VanDerWaalsContact C-N 3.3Å; H480-D482 PolarHBondContact O-N 2.96Å
481	Q	79.4	Confident	87.1	Confident	184 Å²	184	52 Å²	52	86%	0.86	25%	0.251	S	S	*	.	T	Hydrogen-bonded Turn	trans	59.1	32.4	176.9	-53.5	-173.3	-49.5	0	0	114.8	A477 R478	A477-Q481 PolarHBondContact O-N 3.03Å; R478-Q481 PolarHBondContact O-N 3.22Å
482	D	83.1	Confident	87.4	Confident	68 Å²	68	51.9 Å²	51.9	36%	0.364	25%	0.25	S	S	.	.			trans	-104.7	114.5	176.4	-175.2	-34.9	0	0	0	110.8	H480 Q484 L485 E486	H480-D482 VanDerWaalsContact C-N 3.3Å; H480-D482 PolarHBondContact O-N 2.96Å; D482-Q484 VanDerWaalsContact C-N 3.31Å; D482-Q484 PolarHBondContact O-N 2.93Å; D482-Q484 WeakPolarHBondContact OD1-CA 3.31Å; D482-Q484 WeakPolarHBondContact OD1-CB 3.15Å; D482-Q484 PolarHBondContact OD1-N 3.38Å; D482-L485 HydrophobicContact CB-CB 4.07Å; D482-L485 HydrophobicContact CB-CD1 3.89Å; D482-L485 HydrophobicContact CB-CG 3.91Å; D482-L485 PolarHBondContact O-N 2.92Å; D482-L485 PolarHBondContact OD1-N 3.16Å; D482-E486 PolarHBondContact O-N 3.31Å
483	E	86.3	Confident	87.6	Confident	163 Å²	163	51.6 Å²	51.6	76%	0.762	25%	0.249	S	C	*	.	H	α-helix	trans	-63.1	-30.8	-179.1	-65	-171.9	164.9	0	0	113.8	K487	E483-K487 WeakPolarHBondContact O-CB 3.47Å; E483-K487 PolarHBondContact O-N 3.04Å; E483-K487 VanDerWaalsContact O-N 3.08Å
484	Q	88.9	Confident	87.7	Confident	104 Å²	104	51.8 Å²	51.8	49%	0.486	25%	0.25	S	C	.	.	H	α-helix	trans	-71.9	-43	177.4	-63.3	-59.9	-56.2	0	0	110.4	D482 E486 K487 Y488	D482-Q484 VanDerWaalsContact C-N 3.31Å; D482-Q484 PolarHBondContact O-N 2.93Å; D482-Q484 WeakPolarHBondContact OD1-CA 3.31Å; D482-Q484 WeakPolarHBondContact OD1-CB 3.15Å; D482-Q484 PolarHBondContact OD1-N 3.38Å; Q484-E486 VanDerWaalsContact C-N 3.35Å; Q484-K487 WeakPolarHBondContact O-CB 3.34Å; Q484-K487 PolarHBondContact O-N 2.81Å; Q484-Y488 WeakPolarHBondContact O-CD2 3.49Å; Q484-Y488 VanDerWaalsContact O-CG 3.31Å; Q484-Y488 PolarHBondContact O-N 3.47Å
485	L	89.5	Confident	87.9	Confident	32 Å²	32	51.8 Å²	51.8	17%	0.168	25%	0.25	C	C	.	.	H	α-helix	trans	-67.2	-36.1	176.1	-58.1	-177.6	0	0	0	111.5	W235 F296 A477 D482 K487 Y488 G489	W235-L485 HydrophobicContact CZ2-CB 4.07Å; W235-L485 HydrophobicContact CZ2-CD2 3.95Å; F296-L485 HydrophobicContact CD1-CD1 4.16Å; F296-L485 HydrophobicContact CE1-CB 4.47Å; F296-L485 HydrophobicContact CE1-CD1 3.61Å; F296-L485 HydrophobicContact CZ-CD1 4.34Å; A477-L485 VanDerWaalsContact CB-C 3.42Å; A477-L485 HydrophobicContact CB-CB 3.8Å; A477-L485 WeakPolarHBondContact CB-O 3.24Å; D482-L485 HydrophobicContact CB-CB 4.07Å; D482-L485 HydrophobicContact CB-CD1 3.89Å; D482-L485 HydrophobicContact CB-CG 3.91Å; D482-L485 PolarHBondContact O-N 2.92Å; D482-L485 PolarHBondContact OD1-N 3.16Å; L485-K487 VanDerWaalsContact C-N 3.35Å; L485-Y488 HydrophobicContact CD2-CD2 4.06Å; L485-Y488 HydrophobicContact CD2-CE2 4.38Å; L485-Y488 PolarHBondContact O-N 3.48Å; L485-G489 PolarHBondContact O-N 3.26Å
486	E	90.3	Very high	88.2	Confident	64 Å²	64	51 Å²	51	30%	0.299	25%	0.246	S	C	.	.	H	α-helix	trans	-62.7	-42.7	173.8	174.6	157.2	-163.5	0	0	111.1	L474 R478 D482 Q484 Y488 G489 M490	L474-E486 HydrophobicContact CD1-CG 3.81Å; R478-E486 HydrophobicContact CG-CG 4.27Å; R478-E486 IonicContact CZ-OE1 3.62Å; R478-E486 IonicContact NE-OE1 3.42Å; R478-E486 PolarHBondContact NE-OE1 3.06Å; R478-E486 IonicContact NH2-OE1 2.7Å; R478-E486 PolarHBondContact NH2-OE1 2.91Å; D482-E486 PolarHBondContact O-N 3.31Å; Q484-E486 VanDerWaalsContact C-N 3.35Å; E486-Y488 PolarHBondContact O-N 3.13Å; E486-G489 CarbonylContact O-C 3.59Å; E486-G489 PolarHBondContact O-N 2.87Å; E486-G489 VanDerWaalsContact O-N 3.17Å; E486-M490 HydrophobicContact CG-CG 4.48Å; E486-M490 WeakPolarHBondContact O-CG 3.45Å; E486-M490 PolarHBondContact O-N 3.31Å
487	K	89.4	Confident	88.6	Confident	107 Å²	107	51 Å²	51	47%	0.465	25%	0.246	S	C	.	.	H	α-helix	trans	-60	-45.2	175.1	-174.9	-179.7	175.1	-170.7	0	112.2	E483 Q484 L485 G489 M490 D491	E483-K487 WeakPolarHBondContact O-CB 3.47Å; E483-K487 PolarHBondContact O-N 3.04Å; E483-K487 VanDerWaalsContact O-N 3.08Å; Q484-K487 WeakPolarHBondContact O-CB 3.34Å; Q484-K487 PolarHBondContact O-N 2.81Å; L485-K487 VanDerWaalsContact C-N 3.35Å; K487-G489 VanDerWaalsContact C-N 3.32Å; K487-G489 PolarHBondContact O-N 3.26Å; K487-M490 PolarHBondContact O-N 3.26Å; K487-D491 PolarHBondContact O-N 3.35Å
488	Y	91.3	Very high	88.8	Confident	49 Å²	49	51.9 Å²	51.9	19%	0.192	25%	0.25	C	S	.	.	H	α-helix	trans	-62.9	-38.5	174.8	-57.9	-28.9	0	0	0	112	L231 P232 W235 Q484 L485 E486 D491 V492	L231-Y488 HydrophobicContact CD2-CD1 3.28Å; L231-Y488 HydrophobicContact CD2-CE1 3.99Å; L231-Y488 HydrophobicContact CD2-CG 3.79Å; P232-Y488 HydrophobicContact CG-CD2 4.42Å; P232-Y488 HydrophobicContact CG-CE2 3.71Å; W235-Y488 AromaticContact CD1-CD2 3.69Å; W235-Y488 HydrophobicContact CD2-CD2 4.18Å; W235-Y488 HydrophobicContact CD2-CG 4.3Å; W235-Y488 AromaticContact CE2-CD2 3.98Å; W235-Y488 HydrophobicContact CG-CD2 4.03Å; W235-Y488 HydrophobicContact CG-CG 4.28Å; W235-Y488 AromaticContact NE1-CD2 3.66Å; Q484-Y488 WeakPolarHBondContact O-CD2 3.49Å; Q484-Y488 VanDerWaalsContact O-CG 3.31Å; Q484-Y488 PolarHBondContact O-N 3.47Å; L485-Y488 HydrophobicContact CD2-CD2 4.06Å; L485-Y488 HydrophobicContact CD2-CE2 4.38Å; L485-Y488 PolarHBondContact O-N 3.48Å; E486-Y488 PolarHBondContact O-N 3.13Å; Y488-D491 PolarHBondContact O-N 2.72Å; Y488-V492 WeakPolarHBondContact O-CG2 3.4Å; Y488-V492 PolarHBondContact O-N 3.4Å
489	G	91.2	Very high	89.2	Confident	0 Å²	0	49.7 Å²	49.7	0%	0	24%	0.242	C	C	.	.	H	α-helix	trans	-61.6	-40.6	172.6	0	0	0	0	0	113.4	L485 E486 K487 V492 L493	L485-G489 PolarHBondContact O-N 3.26Å; E486-G489 CarbonylContact O-C 3.59Å; E486-G489 PolarHBondContact O-N 2.87Å; E486-G489 VanDerWaalsContact O-N 3.17Å; K487-G489 VanDerWaalsContact C-N 3.32Å; K487-G489 PolarHBondContact O-N 3.26Å; G489-V492 PolarHBondContact O-N 3.43Å; G489-L493 WeakPolarHBondContact O-CB 3.02Å; G489-L493 PolarHBondContact O-N 2.9Å
490	M	89.8	Confident	89.7	Confident	46 Å²	46	46.3 Å²	46.3	23%	0.227	22%	0.218	C	C	.	.	H	α-helix	trans	-66.6	-38.6	175.6	-74.3	-59	-58.3	0	0	112.1	L474 E486 K487 L493 T494	L474-M490 HydrophobicContact CD1-CG 3.84Å; L474-M490 HydrophobicContact CD1-SD 3.81Å; L474-M490 HydrophobicContact CD2-SD 3.47Å; L474-M490 WeakPolarHBondContact CD2-SD 3.34Å; L474-M490 HydrophobicContact CG-SD 4.3Å; E486-M490 HydrophobicContact CG-CG 4.48Å; E486-M490 WeakPolarHBondContact O-CG 3.45Å; E486-M490 PolarHBondContact O-N 3.31Å; K487-M490 PolarHBondContact O-N 3.26Å; M490-L493 PolarHBondContact O-N 3.06Å; M490-T494 VanDerWaalsContact O-CB 3.27Å; M490-T494 WeakPolarHBondContact O-CB 3.36Å; M490-T494 PolarHBondContact O-N 2.87Å; M490-T494 PolarHBondContact O-OG1 2.99Å
491	D	90.4	Very high	90.2	Very high	24 Å²	24	44 Å²	44	13%	0.128	21%	0.209	C	C	.	.	H	α-helix	trans	-63.7	-46.1	174	-76.1	-29	0	0	0	111	M229 L231 K487 Y488 L493 T494 V495	M229-D491 HydrophobicContact CE-CB 3.79Å; L231-D491 HydrophobicContact CD2-CB 4.47Å; K487-D491 PolarHBondContact O-N 3.35Å; Y488-D491 PolarHBondContact O-N 2.72Å; D491-L493 PolarHBondContact O-N 3.01Å; D491-T494 PolarHBondContact O-N 3.47Å; D491-V495 WeakPolarHBondContact O-CG2 3.28Å; D491-V495 PolarHBondContact O-N 2.99Å
492	V	92.6	Very high	90.8	Very high	0 Å²	0	38 Å²	38	0%	0	18%	0.182	C	C	.	.	H	α-helix	trans	-58.6	-48.5	174.3	172.9	0	0	0	0	111.5	W235 I238 L239 V242 Y488 G489 T494 V495 A496	W235-V492 HydrophobicContact CE3-CG2 3.94Å; W235-V492 HydrophobicContact CZ3-CG2 4.31Å; I238-V492 HydrophobicContact CG2-CG1 4.31Å; I238-V492 HydrophobicContact CG2-CG2 4.32Å; L239-V492 HydrophobicContact CB-CG2 4.19Å; V242-V492 HydrophobicContact CG2-CG1 4.14Å; Y488-V492 WeakPolarHBondContact O-CG2 3.4Å; Y488-V492 PolarHBondContact O-N 3.4Å; G489-V492 PolarHBondContact O-N 3.43Å; V492-T494 VanDerWaalsContact C-N 3.32Å; V492-T494 PolarHBondContact O-N 3.33Å; V492-V495 PolarHBondContact O-N 3.04Å; V492-A496 WeakPolarHBondContact O-CB 3.38Å; V492-A496 PolarHBondContact O-N 3.49Å
493	L	91.6	Very high	91.3	Very high	1 Å²	1	34.8 Å²	34.8	1%	0.005	17%	0.165	C	C	.	.	H	α-helix	trans	-64.2	-37	-179.7	-177.3	60.3	0	0	0	112	I406 E409 L474 G489 M490 D491 A496 F497	I406-L493 HydrophobicContact CG2-CD1 4.08Å; E409-L493 HydrophobicContact CB-CD2 3.72Å; E409-L493 HydrophobicContact CG-CD2 4.07Å; L474-L493 HydrophobicContact CD2-CD2 3.48Å; L474-L493 VanDerWaalsContact CD2-CD2 3.48Å; G489-L493 WeakPolarHBondContact O-CB 3.02Å; G489-L493 PolarHBondContact O-N 2.9Å; M490-L493 PolarHBondContact O-N 3.06Å; D491-L493 PolarHBondContact O-N 3.01Å; L493-A496 PolarHBondContact O-N 3.47Å; L493-F497 WeakPolarHBondContact O-CB 3.4Å; L493-F497 PolarHBondContact O-N 3.31Å
494	T	90.8	Very high	91.5	Very high	4 Å²	4	27.1 Å²	27.1	3%	0.025	13%	0.13	C	C	.	.	H	α-helix	trans	-64.1	-48.5	176.6	-64.4	0	0	0	0	111.3	L415 M490 D491 V492 A496 F497 L498	L415-T494 HydrophobicContact CD1-CG2 4.3Å; L415-T494 HydrophobicContact CD2-CG2 3.44Å; L415-T494 VanDerWaalsContact CD2-CG2 3.44Å; M490-T494 VanDerWaalsContact O-CB 3.27Å; M490-T494 WeakPolarHBondContact O-CB 3.36Å; M490-T494 PolarHBondContact O-N 2.87Å; M490-T494 PolarHBondContact O-OG1 2.99Å; D491-T494 PolarHBondContact O-N 3.47Å; V492-T494 VanDerWaalsContact C-N 3.32Å; V492-T494 PolarHBondContact O-N 3.33Å; T494-A496 VanDerWaalsContact C-N 3.3Å; T494-A496 PolarHBondContact O-N 3.08Å; T494-F497 PolarHBondContact O-N 3.47Å; T494-L498 HydrophobicContact CG2-CD1 4.06Å; T494-L498 WeakPolarHBondContact O-CG 3.22Å; T494-L498 PolarHBondContact O-N 3.06Å
495	V	92.4	Very high	91.5	Very high	0 Å²	0	23.6 Å²	23.6	0%	0	12%	0.116	C	C	.	.	H	α-helix	trans	-64.8	-38.5	178.1	-176.5	0	0	0	0	110.4	M229 L239 L243 C423 D491 V492 L498 A499	M229-V495 HydrophobicContact CE-CG2 3.7Å; M229-V495 HydrophobicContact SD-CG2 3.97Å; L239-V495 HydrophobicContact CD1-CB 3.71Å; L239-V495 HydrophobicContact CD1-CG1 3.75Å; L239-V495 HydrophobicContact CD1-CG2 4.28Å; L239-V495 HydrophobicContact CD2-CB 4.39Å; L239-V495 HydrophobicContact CD2-CG1 4.42Å; L239-V495 HydrophobicContact CD2-CG2 4.08Å; L243-V495 HydrophobicContact CD1-CG1 3.92Å; L243-V495 HydrophobicContact CD2-CG1 4.22Å; L243-V495 HydrophobicContact CG-CG1 4.44Å; C423-V495 HydrophobicContact CB-CG2 3.81Å; C423-V495 WeakPolarHBondContact SG-CG2 3.46Å; D491-V495 WeakPolarHBondContact O-CG2 3.28Å; D491-V495 PolarHBondContact O-N 2.99Å; V492-V495 PolarHBondContact O-N 3.04Å; V495-L498 PolarHBondContact O-N 3.16Å; V495-A499 VanDerWaalsContact O-CB 3.28Å; V495-A499 WeakPolarHBondContact O-CB 3.41Å; V495-A499 PolarHBondContact O-N 2.91Å
496	A	93.3	Very high	91.6	Very high	1 Å²	1	25.8 Å²	25.8	1%	0.008	13%	0.127	C	C	.	.	H	α-helix	trans	-59.6	-48.9	173.4	0	0	0	0	0	111.8	V242 Q466 V492 L493 T494 L498 A499 I500	V242-A496 HydrophobicContact CG1-CB 3.83Å; Q466-A496 HydrophobicContact CB-CB 4.33Å; V492-A496 WeakPolarHBondContact O-CB 3.38Å; V492-A496 PolarHBondContact O-N 3.49Å; L493-A496 PolarHBondContact O-N 3.47Å; T494-A496 VanDerWaalsContact C-N 3.3Å; T494-A496 PolarHBondContact O-N 3.08Å; A496-L498 PolarHBondContact O-N 3.28Å; A496-A499 WeakPolarHBondContact O-CB 3.41Å; A496-A499 PolarHBondContact O-N 2.98Å; A496-I500 WeakPolarHBondContact O-CD1 3.35Å; A496-I500 WeakPolarHBondContact O-CG1 3.43Å; A496-I500 PolarHBondContact O-N 3.16Å
497	F	92.5	Very high	91.6	Very high	6 Å²	6	22.8 Å²	22.8	3%	0.026	11%	0.113	C	C	.	.	H	α-helix	trans	-57.4	-48.4	176	172.3	-86.9	0	0	0	112.2	L152 F156 V410 L493 T494 A499 I500 L501	L152-F497 HydrophobicContact CD1-CD2 3.85Å; L152-F497 HydrophobicContact CD1-CE2 4.14Å; L152-F497 HydrophobicContact CD2-CD2 3.89Å; L152-F497 HydrophobicContact CD2-CE2 3.34Å; L152-F497 HydrophobicContact CD2-CZ 3.87Å; L152-F497 HydrophobicContact CG-CD2 3.91Å; L152-F497 HydrophobicContact CG-CE2 3.68Å; F156-F497 HydrophobicContact CB-CE2 4.17Å; F156-F497 HydrophobicContact CB-CZ 4.12Å; F156-F497 HydrophobicContact CD2-CE1 4.11Å; F156-F497 AromaticContact CD2-CE2 3.97Å; F156-F497 HydrophobicContact CD2-CE2 3.97Å; F156-F497 AromaticContact CD2-CZ 3.38Å; F156-F497 HydrophobicContact CD2-CZ 3.38Å; F156-F497 HydrophobicContact CE2-CE1 4.18Å; F156-F497 AromaticContact CE2-CZ 3.88Å; F156-F497 HydrophobicContact CE2-CZ 3.88Å; F156-F497 HydrophobicContact CG-CE2 4.36Å; F156-F497 AromaticContact CG-CZ 3.85Å; F156-F497 HydrophobicContact CG-CZ 3.85Å; V410-F497 HydrophobicContact CB-CD2 4.21Å; V410-F497 HydrophobicContact CB-CE2 4.37Å; V410-F497 HydrophobicContact CB-CG 4.31Å; V410-F497 HydrophobicContact CG1-CD1 4.01Å; V410-F497 HydrophobicContact CG1-CE1 4.16Å; V410-F497 HydrophobicContact CG1-CG 4.23Å; V410-F497 HydrophobicContact CG1-CZ 4.48Å; V410-F497 HydrophobicContact CG2-CB 3.89Å; V410-F497 HydrophobicContact CG2-CD1 4.4Å; V410-F497 HydrophobicContact CG2-CD2 3.81Å; V410-F497 HydrophobicContact CG2-CE2 4.45Å; V410-F497 HydrophobicContact CG2-CG 3.79Å; L493-F497 WeakPolarHBondContact O-CB 3.4Å; L493-F497 PolarHBondContact O-N 3.31Å; T494-F497 PolarHBondContact O-N 3.47Å; F497-A499 VanDerWaalsContact C-N 3.32Å; F497-A499 PolarHBondContact O-N 2.83Å; F497-I500 PolarHBondContact O-N 3.26Å; F497-L501 HydrophobicContact CE1-CD2 3.84Å; F497-L501 HydrophobicContact CZ-CD2 4.35Å; F497-L501 WeakPolarHBondContact O-CB 3.33Å; F497-L501 PolarHBondContact O-N 3.46Å
498	L	92.5	Very high	91.5	Very high	18 Å²	18	17.9 Å²	17.9	9%	0.094	9%	0.092	C	C	.	.	H	α-helix	trans	-62.9	-38.8	177.9	-69.4	169.9	0	0	0	111.7	V420 C423 I424 T494 V495 A496 L501 I502	V420-L498 HydrophobicContact CG1-CD1 4.11Å; V420-L498 HydrophobicContact CG1-CD2 4.41Å; C423-L498 HydrophobicContact CB-CD1 3.61Å; I424-L498 HydrophobicContact CG1-CD1 4.42Å; T494-L498 HydrophobicContact CG2-CD1 4.06Å; T494-L498 WeakPolarHBondContact O-CG 3.22Å; T494-L498 PolarHBondContact O-N 3.06Å; V495-L498 PolarHBondContact O-N 3.16Å; A496-L498 PolarHBondContact O-N 3.28Å; L498-L501 PolarHBondContact O-N 3.06Å; L498-I502 WeakPolarHBondContact O-CB 3.27Å; L498-I502 VanDerWaalsContact O-CG1 3.31Å; L498-I502 WeakPolarHBondContact O-CG1 3.31Å; L498-I502 PolarHBondContact O-N 3.47Å
499	A	94	Very high	91.4	Very high	0 Å²	0	18.7 Å²	18.7	0%	0	10%	0.1	C	C	.	.	H	α-helix	trans	-62.9	-42.6	175.6	0	0	0	0	0	112.4	L243 L427 K462 V495 A496 F497 T503	L243-A499 HydrophobicContact CD2-CB 3.72Å; L427-A499 HydrophobicContact CD1-CB 3.75Å; L427-A499 HydrophobicContact CD2-CB 4.09Å; K462-A499 HydrophobicContact CB-CB 4.42Å; K462-A499 HydrophobicContact CD-CB 3.96Å; V495-A499 VanDerWaalsContact O-CB 3.28Å; V495-A499 WeakPolarHBondContact O-CB 3.41Å; V495-A499 PolarHBondContact O-N 2.91Å; A496-A499 WeakPolarHBondContact O-CB 3.41Å; A496-A499 PolarHBondContact O-N 2.98Å; F497-A499 VanDerWaalsContact C-N 3.32Å; F497-A499 PolarHBondContact O-N 2.83Å; A499-T503 WeakPolarHBondContact O-CB 3.44Å; A499-T503 WeakPolarHBondContact O-CG2 3.27Å; A499-T503 PolarHBondContact O-N 3.35Å; A499-T503 PolarHBondContact O-OG1 2.8Å
500	I	93	Very high	91.4	Very high	1 Å²	1	20.4 Å²	20.4	1%	0.005	11%	0.11	C	C	.	.	H	α-helix	trans	-63.6	-49.7	174.7	-57.7	159.3	0	0	0	110.4	L152 F403 A463 Q466 A467 A496 F497 I502 A504	L152-I500 HydrophobicContact CD1-CB 4.08Å; L152-I500 HydrophobicContact CD1-CD1 3.98Å; L152-I500 HydrophobicContact CD1-CG2 3.8Å; F403-I500 HydrophobicContact CE1-CG2 4.35Å; A463-I500 HydrophobicContact CB-CG2 4.39Å; Q466-I500 HydrophobicContact CB-CD1 4.04Å; Q466-I500 HydrophobicContact CB-CG1 3.84Å; A467-I500 HydrophobicContact CB-CD1 4Å; A496-I500 WeakPolarHBondContact O-CD1 3.35Å; A496-I500 WeakPolarHBondContact O-CG1 3.43Å; A496-I500 PolarHBondContact O-N 3.16Å; F497-I500 PolarHBondContact O-N 3.26Å; I500-I502 PolarHBondContact O-N 3.17Å; I500-A504 WeakPolarHBondContact O-CB 3.42Å; I500-A504 PolarHBondContact O-N 3.35Å
501	L	91.8	Very high	91.5	Very high	53 Å²	53	18.2 Å²	18.2	28%	0.277	10%	0.099	S	C	.	.	H	α-helix	trans	-59.4	-42.1	-176.9	177.2	58.2	0	0	0	112.7	L149 L153 F497 L498 P505	L149-L501 HydrophobicContact CD1-CD1 3.87Å; L153-L501 HydrophobicContact CD2-CD1 3.98Å; F497-L501 HydrophobicContact CE1-CD2 3.84Å; F497-L501 HydrophobicContact CZ-CD2 4.35Å; F497-L501 WeakPolarHBondContact O-CB 3.33Å; F497-L501 PolarHBondContact O-N 3.46Å; L498-L501 PolarHBondContact O-N 3.06Å; L501-P505 WeakPolarHBondContact O-CD 3.49Å; L501-P505 VanDerWaalsContact O-CG 3.3Å; L501-P505 WeakPolarHBondContact O-CG 3.5Å
502	I	92.4	Very high	91.3	Very high	56 Å²	56	18.2 Å²	18.2	29%	0.287	11%	0.105	S	C	.	.	H	α-helix	trans	-86.9	-51	-175.6	-64.3	168.6	0	0	0	111.2	I424 L427 L498 I500 P505 I506	I424-I502 HydrophobicContact CD1-CD1 4.42Å; I424-I502 HydrophobicContact CG1-CD1 4.09Å; L427-I502 HydrophobicContact CD2-CD1 4.31Å; L498-I502 WeakPolarHBondContact O-CB 3.27Å; L498-I502 VanDerWaalsContact O-CG1 3.31Å; L498-I502 WeakPolarHBondContact O-CG1 3.31Å; L498-I502 PolarHBondContact O-N 3.47Å; I500-I502 PolarHBondContact O-N 3.17Å; I502-P505 WeakPolarHBondContact O-CD 3.32Å; I502-I506 HydrophobicContact CG2-CD1 3.76Å; I502-I506 WeakPolarHBondContact O-CB 3.39Å; I502-I506 WeakPolarHBondContact O-CD1 3.36Å; I502-I506 VanDerWaalsContact O-CG1 3.23Å; I502-I506 WeakPolarHBondContact O-CG1 3.32Å
503	T	93.8	Very high	91.2	Very high	2 Å²	2	21.2 Å²	21.2	1%	0.012	12%	0.12	C	C	.	.	H	α-helix	trans	-87.3	-26.3	-165.1	73.2	0	0	0	0	114.2	L427 L431 K462 A499 G507	L427-T503 HydrophobicContact CD1-CG2 4.31Å; L427-T503 HydrophobicContact CD2-CG2 4.27Å; L431-T503 HydrophobicContact CD1-CG2 3.66Å; K462-T503 WeakPolarHBondContact CA-OG1 3.33Å; K462-T503 WeakPolarHBondContact CB-OG1 3.45Å; K462-T503 HydrophobicContact CD-CG2 4.38Å; K462-T503 PolarHBondContact N-OG1 3.05Å; K462-T503 PolarHBondContact O-OG1 3.46Å; A499-T503 WeakPolarHBondContact O-CB 3.44Å; A499-T503 WeakPolarHBondContact O-CG2 3.27Å; A499-T503 PolarHBondContact O-N 3.35Å; A499-T503 PolarHBondContact O-OG1 2.8Å; T503-G507 WeakPolarHBondContact O-CA 3.38Å; T503-G507 PolarHBondContact O-N 2.98Å
504	A	90.3	Very high	91.1	Very high	2 Å²	2	21.8 Å²	21.8	2%	0.017	13%	0.125	C	C	.	.	H	α-helix	trans	-61.2	-51.1	176	0	0	0	0	0	112.7	P146 V250 K462 A463 I500 A508	P146-A504 HydrophobicContact CG-CB 4.45Å; V250-A504 HydrophobicContact CG2-CB 4.29Å; K462-A504 WeakPolarHBondContact O-CB 3.41Å; A463-A504 HydrophobicContact CB-CB 4.26Å; I500-A504 WeakPolarHBondContact O-CB 3.42Å; I500-A504 PolarHBondContact O-N 3.35Å; A504-A508 WeakPolarHBondContact O-CB 3.28Å; A504-A508 PolarHBondContact O-N 3.1Å; A504-A508 VanDerWaalsContact O-N 3.07Å
505	P	89.6	Confident	91	Very high	30 Å²	30	21.6 Å²	21.6	20%	0.195	12%	0.124	C	C	.	.	H	α-helix	trans	-69.9	-40.6	177.6	26.9	-34	0	0	0	112.5	L145 L149 L501 I502 A508 L509	L145-P505 HydrophobicContact CD2-CB 4.33Å; L149-P505 HydrophobicContact CD2-CB 4.23Å; L149-P505 HydrophobicContact CD2-CG 4.12Å; L501-P505 WeakPolarHBondContact O-CD 3.49Å; L501-P505 VanDerWaalsContact O-CG 3.3Å; L501-P505 WeakPolarHBondContact O-CG 3.5Å; I502-P505 WeakPolarHBondContact O-CD 3.32Å; P505-A508 PolarHBondContact O-N 2.93Å; P505-L509 VanDerWaalsContact O-CB 3.23Å; P505-L509 WeakPolarHBondContact O-CB 3.5Å; P505-L509 PolarHBondContact O-N 2.76Å
506	I	90.8	Very high	90.8	Very high	78 Å²	78	24.4 Å²	24.4	40%	0.4	14%	0.142	S	C	.	.	H	α-helix	trans	-63	-45.3	177.4	-67.7	174.7	0	0	0	110.6	I502 L509 V510	I502-I506 HydrophobicContact CG2-CD1 3.76Å; I502-I506 WeakPolarHBondContact O-CB 3.39Å; I502-I506 WeakPolarHBondContact O-CD1 3.36Å; I502-I506 VanDerWaalsContact O-CG1 3.23Å; I502-I506 WeakPolarHBondContact O-CG1 3.32Å; I506-L509 WeakPolarHBondContact O-CB 3.38Å; I506-L509 PolarHBondContact O-N 2.95Å; I506-V510 HydrophobicContact CG2-CG2 4.19Å; I506-V510 VanDerWaalsContact O-CB 3.31Å; I506-V510 WeakPolarHBondContact O-CB 3.48Å; I506-V510 WeakPolarHBondContact O-CG2 3.4Å; I506-V510 PolarHBondContact O-N 2.91Å
507	G	90.4	Very high	90.5	Very high	0 Å²	0	33.8 Å²	33.8	0%	0	18%	0.177	C	C	.	.	H	α-helix	trans	-64.1	-43.1	179.2	0	0	0	0	0	112.6	T503 V510 I511	T503-G507 WeakPolarHBondContact O-CA 3.38Å; T503-G507 PolarHBondContact O-N 2.98Å; G507-V510 PolarHBondContact O-N 3.17Å; G507-I511 WeakPolarHBondContact O-CD1 3.2Å; G507-I511 VanDerWaalsContact O-CG1 3.26Å; G507-I511 WeakPolarHBondContact O-CG1 3.47Å; G507-I511 PolarHBondContact O-N 3.17Å
508	A	87.6	Confident	90.4	Very high	4 Å²	4	35.2 Å²	35.2	3%	0.033	19%	0.185	C	C	.	.	H	α-helix	trans	-59.7	-51.8	173.3	0	0	0	0	0	111.5	P143 P146 V250 A504 P505 V510 I511 G512	P143-A508 HydrophobicContact CG-CB 4.35Å; P143-A508 WeakPolarHBondContact CG-O 3.3Å; P146-A508 HydrophobicContact CG-CB 4.41Å; V250-A508 HydrophobicContact CG1-CB 3.94Å; A504-A508 WeakPolarHBondContact O-CB 3.28Å; A504-A508 PolarHBondContact O-N 3.1Å; A504-A508 VanDerWaalsContact O-N 3.07Å; P505-A508 PolarHBondContact O-N 2.93Å; A508-V510 VanDerWaalsContact C-N 3.33Å; A508-V510 PolarHBondContact O-N 2.77Å; A508-I511 PolarHBondContact O-N 3.3Å; A508-G512 PolarHBondContact O-N 3.44Å
509	L	89	Confident	90.2	Very high	67 Å²	67	34.9 Å²	34.9	35%	0.351	18%	0.183	S	C	.	.	H	α-helix	trans	-51.7	-49.6	175.3	166.6	62.9	0	0	0	111.9	L142 P505 I506 G512 L513	L142-L509 HydrophobicContact CD1-CD1 4.08Å; L142-L509 HydrophobicContact CD2-CD1 3.29Å; L142-L509 HydrophobicContact CG-CD1 4.31Å; P505-L509 VanDerWaalsContact O-CB 3.23Å; P505-L509 WeakPolarHBondContact O-CB 3.5Å; P505-L509 PolarHBondContact O-N 2.76Å; I506-L509 WeakPolarHBondContact O-CB 3.38Å; I506-L509 PolarHBondContact O-N 2.95Å; L509-G512 PolarHBondContact O-N 3.08Å; L509-L513 HydrophobicContact CD1-CD1 3.49Å; L509-L513 VanDerWaalsContact CD1-CD1 3.49Å; L509-L513 HydrophobicContact CD1-CG 4.07Å; L509-L513 HydrophobicContact CG-CD1 4.33Å; L509-L513 WeakPolarHBondContact O-CB 3.29Å; L509-L513 WeakPolarHBondContact O-CG 3.3Å; L509-L513 PolarHBondContact O-N 3.09Å
510	V	91.4	Very high	89.9	Confident	35 Å²	35	39.4 Å²	39.4	21%	0.212	20%	0.204	C	C	.	.	H	α-helix	trans	-65.2	-47.1	-178.7	167.4	0	0	0	0	111.3	L457 I506 G507 A508 G512 L513 A514	L457-V510 HydrophobicContact CB-CG1 3.66Å; L457-V510 HydrophobicContact CD1-CG1 4.11Å; L457-V510 HydrophobicContact CD2-CG1 4.29Å; L457-V510 HydrophobicContact CG-CG1 4.23Å; I506-V510 HydrophobicContact CG2-CG2 4.19Å; I506-V510 VanDerWaalsContact O-CB 3.31Å; I506-V510 WeakPolarHBondContact O-CB 3.48Å; I506-V510 WeakPolarHBondContact O-CG2 3.4Å; I506-V510 PolarHBondContact O-N 2.91Å; G507-V510 PolarHBondContact O-N 3.17Å; A508-V510 VanDerWaalsContact C-N 3.33Å; A508-V510 PolarHBondContact O-N 2.77Å; V510-G512 PolarHBondContact O-N 3.25Å; V510-L513 PolarHBondContact O-N 3.45Å; V510-A514 WeakPolarHBondContact O-CB 3.37Å; V510-A514 PolarHBondContact O-N 3.31Å
511	I	90.8	Very high	89.6	Confident	1 Å²	1	45.2 Å²	45.2	1%	0.005	23%	0.23	C	C	.	.	H	α-helix	trans	-60.8	-45.6	178	-67.3	162.3	0	0	0	110.8	V251 M255 L258 F454 A458 P461 G507 A508 L513 G515	V251-I511 HydrophobicContact CG2-CD1 4.31Å; M255-I511 HydrophobicContact CE-CD1 4.24Å; M255-I511 HydrophobicContact CE-CG1 4.34Å; M255-I511 HydrophobicContact CE-CG2 3.78Å; L258-I511 HydrophobicContact CD1-CG2 3.94Å; F454-I511 HydrophobicContact CE2-CG2 4.3Å; F454-I511 HydrophobicContact CZ-CG2 4.22Å; A458-I511 HydrophobicContact CB-CD1 4.39Å; A458-I511 HydrophobicContact CB-CG1 4.07Å; P461-I511 HydrophobicContact CG-CD1 3.85Å; G507-I511 WeakPolarHBondContact O-CD1 3.2Å; G507-I511 VanDerWaalsContact O-CG1 3.26Å; G507-I511 WeakPolarHBondContact O-CG1 3.47Å; G507-I511 PolarHBondContact O-N 3.17Å; A508-I511 PolarHBondContact O-N 3.3Å; I511-L513 PolarHBondContact O-N 3.07Å; I511-G515 PolarHBondContact O-N 3.25Å
512	G	87.5	Confident	89	Confident	24 Å²	24	44.1 Å²	44.1	25%	0.247	23%	0.228	C	C	.	.	H	α-helix	trans	-66	-36.1	-178	0	0	0	0	0	114.2	A508 L509 V510 P516	A508-G512 PolarHBondContact O-N 3.44Å; L509-G512 PolarHBondContact O-N 3.08Å; V510-G512 PolarHBondContact O-N 3.25Å; G512-P516 WeakPolarHBondContact O-CD 3.35Å
513	L	88.8	Confident	87.7	Confident	63 Å²	63	49.3 Å²	49.3	33%	0.33	25%	0.251	S	S	.	.	H	α-helix	trans	-83.2	-36.6	176.9	-69.8	-178.3	0	0	0	113.2	L142 L509 V510 I511 R517	L142-L513 HydrophobicContact CD2-CD1 4.29Å; L142-L513 HydrophobicContact CD2-CD2 4.07Å; L142-L513 HydrophobicContact CD2-CG 4.13Å; L509-L513 HydrophobicContact CD1-CD1 3.49Å; L509-L513 VanDerWaalsContact CD1-CD1 3.49Å; L509-L513 HydrophobicContact CD1-CG 4.07Å; L509-L513 HydrophobicContact CG-CD1 4.33Å; L509-L513 WeakPolarHBondContact O-CB 3.29Å; L509-L513 WeakPolarHBondContact O-CG 3.3Å; L509-L513 PolarHBondContact O-N 3.09Å; V510-L513 PolarHBondContact O-N 3.45Å; I511-L513 PolarHBondContact O-N 3.07Å; L513-R517 WeakPolarHBondContact O-CD 3.49Å; L513-R517 WeakPolarHBondContact O-CG 3.29Å
514	A	89.9	Confident	85.6	Confident	12 Å²	12	55.2 Å²	55.2	10%	0.099	29%	0.287	C	S	.	.	H	α-helix	trans	-80.9	-35.9	-176	0	0	0	0	0	112.3	F454 V510 R517 L518	F454-A514 HydrophobicContact CD2-CB 4.03Å; F454-A514 HydrophobicContact CE2-CB 4.5Å; V510-A514 WeakPolarHBondContact O-CB 3.37Å; V510-A514 PolarHBondContact O-N 3.31Å; A514-R517 PolarHBondContact O-N 2.9Å; A514-R517 VanDerWaalsContact O-N 3.16Å; A514-L518 HydrophobicContact CB-CD1 3.97Å; A514-L518 HydrophobicContact CB-CG 4.47Å; A514-L518 VanDerWaalsContact O-CB 3.28Å; A514-L518 WeakPolarHBondContact O-CB 3.39Å; A514-L518 WeakPolarHBondContact O-CG 3.47Å; A514-L518 PolarHBondContact O-N 3.19Å
515	G	89.2	Confident	83.2	Confident	0 Å²	0	59.9 Å²	59.9	0%	0	31%	0.312	C	S	.	.	H	α-helix	trans	-53.5	-60.4	-177.7	0	0	0	0	0	113	I511 R517 L518 L519	I511-G515 PolarHBondContact O-N 3.25Å; G515-R517 PolarHBondContact O-N 3.48Å; G515-R517 VanDerWaalsContact O-N 3.11Å; G515-L518 PolarHBondContact O-N 3.32Å; G515-L519 VanDerWaalsContact O-CB 3.29Å; G515-L519 WeakPolarHBondContact O-CB 3.47Å; G515-L519 PolarHBondContact O-N 3.45Å
516	P	87.3	Confident	80.7	Confident	60 Å²	60	66 Å²	66	39%	0.39	34%	0.335	S	S	.	.	H	α-helix	trans	-65.9	-14.3	-179.5	-22.1	34.9	0	0	0	114.9	L258 Y263 G512	L258-P516 HydrophobicContact CD2-CG 4.25Å; Y263-P516 HydrophobicContact CE1-CB 4.05Å; G512-P516 WeakPolarHBondContact O-CD 3.35Å
517	R	88.6	Confident	78.3	Confident	197 Å²	197	69.5 Å²	69.5	74%	0.743	35%	0.35	S	S	*	.	H	α-helix	trans	-99.3	-28.7	-178.5	-70	-176.9	173.9	-177.2	-1.6	114	L513 A514 G515	L513-R517 WeakPolarHBondContact O-CD 3.49Å; L513-R517 WeakPolarHBondContact O-CG 3.29Å; A514-R517 PolarHBondContact O-N 2.9Å; A514-R517 VanDerWaalsContact O-N 3.16Å; G515-R517 PolarHBondContact O-N 3.48Å; G515-R517 VanDerWaalsContact O-N 3.11Å
518	L	89.1	Confident	75.9	Confident	37 Å²	37	76.3 Å²	76.3	19%	0.194	39%	0.387	C	S	.	.	H	α-helix	trans	-108.8	-28.9	-173.3	-63.9	-176.5	0	0	0	113.4	K450 V453 F454 A514 G515	K450-L518 HydrophobicContact CB-CB 4.17Å; K450-L518 HydrophobicContact CB-CD2 3.97Å; K450-L518 WeakPolarHBondContact CB-O 3.36Å; K450-L518 HydrophobicContact CD-CD2 4.49Å; K450-L518 HydrophobicContact CG-CD2 4.13Å; V453-L518 HydrophobicContact CB-CD1 4.33Å; V453-L518 HydrophobicContact CG1-CD1 3.96Å; F454-L518 HydrophobicContact CB-CB 4Å; F454-L518 HydrophobicContact CB-CD1 3.96Å; A514-L518 HydrophobicContact CB-CD1 3.97Å; A514-L518 HydrophobicContact CB-CG 4.47Å; A514-L518 VanDerWaalsContact O-CB 3.28Å; A514-L518 WeakPolarHBondContact O-CB 3.39Å; A514-L518 WeakPolarHBondContact O-CG 3.47Å; A514-L518 PolarHBondContact O-N 3.19Å; G515-L518 PolarHBondContact O-N 3.32Å
519	L	89.1	Confident	73.6	Confident	10 Å²	10	83.5 Å²	83.5	5%	0.052	42%	0.42	C	S	.	.	S	Bend	trans	-84.9	141	176.8	-62	177.4	0	0	0	111	L258 Y263 V269 E451 F454 G515	L258-L519 HydrophobicContact CD1-CD1 4.17Å; Y263-L519 HydrophobicContact CD1-CB 4.5Å; V269-L519 HydrophobicContact CB-CD2 4.17Å; V269-L519 HydrophobicContact CG1-CD2 3.95Å; V269-L519 HydrophobicContact CG2-CD2 4.29Å; E451-L519 HydrophobicContact CG-CD2 4.38Å; F454-L519 HydrophobicContact CB-CD2 4.38Å; F454-L519 HydrophobicContact CD1-CD1 4.1Å; F454-L519 HydrophobicContact CD1-CD2 3.61Å; F454-L519 HydrophobicContact CD1-CG 4Å; F454-L519 HydrophobicContact CD2-CG 4.45Å; F454-L519 HydrophobicContact CE1-CD1 3.76Å; F454-L519 HydrophobicContact CE1-CD2 4.09Å; F454-L519 HydrophobicContact CE1-CG 4.18Å; F454-L519 HydrophobicContact CE2-CD1 4.39Å; F454-L519 HydrophobicContact CG-CD2 4Å; F454-L519 HydrophobicContact CG-CG 4.12Å; F454-L519 HydrophobicContact CZ-CD1 3.92Å; F454-L519 HydrophobicContact CZ-CG 4.5Å; G515-L519 VanDerWaalsContact O-CB 3.29Å; G515-L519 WeakPolarHBondContact O-CB 3.47Å; G515-L519 PolarHBondContact O-N 3.45Å
520	Q	86.5	Confident	71.1	Confident	95 Å²	95	88.1 Å²	88.1	44%	0.444	44%	0.439	S	S	.	.	P	Polyproline II helix	trans	-69.3	135.7	167.4	-65.1	179.7	-90.5	0	0	108.9	G264 N448	G264-Q520 PolarHBondContact N-O 3.08Å; N448-Q520 PolarHBondContact ND2-OE1 3.13Å
521	K	87.4	Confident	68.3	Low	124 Å²	124	89.4 Å²	89.4	54%	0.539	46%	0.46	S	S	.	.	B	Isolated β-bridge	trans	-86.5	129.5	170.6	-171.6	-177.1	178.5	-173.8	0	107.9	G261 G262 Y263 Q523	G261-K521 WeakPolarHBondContact O-CE 3.38Å; G262-K521 WeakPolarHBondContact O-CA 3.45Å; Y263-K521 HydrophobicContact CD1-CB 4.05Å; Y263-K521 HydrophobicContact CD1-CG 4.46Å; Y263-K521 HydrophobicContact CE1-CB 3.96Å; Y263-K521 HydrophobicContact CE1-CD 4.43Å; Y263-K521 HydrophobicContact CE1-CG 4.29Å; K521-Q523 PolarHBondContact O-N 3.32Å
522	A	79.1	Confident	65.7	Low	29 Å²	29	93.3 Å²	93.3	24%	0.24	49%	0.493	C	S	.	.	P	Polyproline II helix	trans	-54.8	131.6	174.5	0	0	0	0	0	110.2	G262 E266 T524	G262-A522 PolarHBondContact O-N 2.93Å; E266-A522 HydrophobicContact CG-CB 4.2Å; E266-A522 WeakPolarHBondContact OE1-CA 3.44Å; A522-T524 PolarHBondContact O-N 2.93Å
523	Q	66.1	Low	63.3	Low	166 Å²	166	101.1 Å²	101.1	78%	0.776	52%	0.523	S	S	*	.			trans	-73.6	115.1	172.4	-72.4	-176	-36.8	0	0	108.3	K521 N525	K521-Q523 PolarHBondContact O-N 3.32Å; Q523-N525 PolarHBondContact O-N 3.49Å
524	T	49	Very low	60.8	Low	125 Å²	125	102.6 Å²	102.6	77%	0.767	54%	0.544	S	S	*	.			trans	-73.4	104.7	161.7	-44.7	0	0	0	0	105.9	A522 K526	A522-T524 PolarHBondContact O-N 2.93Å; T524-K526 PolarHBondContact O-N 3.03Å; T524-K526 VanDerWaalsContact O-N 3.14Å
525	N	39	Very low	58.2	Low	101 Å²	101	105.3 Å²	105.3	54%	0.54	57%	0.573	S	S	.	*			trans	-57.8	119.9	175.3	-75	3.3	0	0	0	108.4	Q523	Q523-N525 PolarHBondContact O-N 3.49Å
526	K	38.6	Very low	55.5	Low	157 Å²	157	114.6 Å²	114.6	68%	0.683	62%	0.616	S	S	*	*			trans	-85.6	3.4	173.4	-83	-170.4	155.2	-141.3	0	112.9	T524 D528	T524-K526 PolarHBondContact O-N 3.03Å; T524-K526 VanDerWaalsContact O-N 3.14Å; K526-D528 VanDerWaalsContact C-N 3.27Å; K526-D528 PolarHBondContact O-N 3.33Å
527	E	38.8	Very low	52.9	Low	152 Å²	152	120.8 Å²	120.8	71%	0.71	64%	0.64	S	S	*	*	H	α-helix	trans	-75.2	-16.5	-172.2	-62.9	178.3	160.8	0	0	112.6
528	D	41.6	Very low	50.2	Low	143 Å²	143	117.4 Å²	117.4	77%	0.765	64%	0.644	S	S	*	*	H	α-helix	trans	-84.7	-10.1	178.9	-63.1	-33.3	0	0	0	114.2	K526	K526-D528 VanDerWaalsContact C-N 3.27Å; K526-D528 PolarHBondContact O-N 3.33Å
529	E	38.5	Very low	47.5	Very low	156 Å²	156	125 Å²	125	73%	0.729	68%	0.678	S	S	*	*	H	α-helix	trans	-97.4	-35.7	175	-75.1	-174.9	155.1	0	0	112.7	G531	E529-G531 VanDerWaalsContact C-N 3.33Å; E529-G531 PolarHBondContact O-N 2.98Å
530	E	35.9	Very low	44.7	Very low	163 Å²	163	131.1 Å²	131.1	76%	0.762	72%	0.716	S	S	*	*	H	α-helix	trans	-79.5	-13.4	179.6	-71	179.8	173	0	0	113.4	A532	E530-A532 VanDerWaalsContact C-N 3.34Å
531	G	33.7	Very low	42	Very low	63 Å²	63	133 Å²	133	65%	0.649	74%	0.738	S	S	*	*	T	Hydrogen-bonded Turn	trans	-78.6	-9.8	175.3	0	0	0	0	0	115.4	E529	E529-G531 VanDerWaalsContact C-N 3.33Å; E529-G531 PolarHBondContact O-N 2.98Å
532	A	36.2	Very low	39.3	Very low	83 Å²	83	134.1 Å²	134.1	69%	0.686	75%	0.746	S	S	*	*	S	Bend	trans	-97.5	-15.7	-173.4	0	0	0	0	0	114.7	E530	E530-A532 VanDerWaalsContact C-N 3.34Å
533	E	36	Very low	37	Very low	188 Å²	188	142.9 Å²	142.9	88%	0.879	77%	0.772	S	S	*	*	S	Bend	trans	-97.6	-3.1	-179.4	-66.9	-167	153.9	0	0	113.9
534	A	37.3	Very low	35.4	Very low	94 Å²	94	144.2 Å²	144.2	78%	0.777	80%	0.8	S	S	*	*	S	Bend	trans	-104.3	56.9	-179.8	0	0	0	0	0	112.3
535	G	35.5	Very low	34.7	Very low	69 Å²	69	145.2 Å²	145.2	71%	0.711	80%	0.801	S	S	*	*			trans	-156.3	9.4	-168.1	0	0	0	0	0	119.3
536	E	32.8	Very low	34.5	Very low	194 Å²	194	147.5 Å²	147.5	91%	0.907	82%	0.815	S	S	*	*			trans	-133.3	86.9	173.8	-72.7	-167.8	145.2	0	0	112.2
537	E	31.3	Very low	34.3	Very low	190 Å²	190	146.9 Å²	146.9	89%	0.888	82%	0.822	S	S	*	*			trans	-89.5	131.8	151	-75	-167.4	150	0	0	108.5	E539	E537-E539 PolarHBondContact O-N 3.27Å
538	P	33.5	Very low	34	Very low	126 Å²	126	146.6 Å²	146.6	82%	0.818	83%	0.829	S	S	*	*			trans	-79.7	115.5	-178.2	30	-32.7	0	0	0	111.4	T540	P538-T540 PolarHBondContact O-N 2.98Å
539	E	30.9	Very low	33.5	Very low	197 Å²	197	146.9 Å²	146.9	92%	0.921	83%	0.833	S	S	*	*			trans	-59.7	128.6	167.9	-79.8	-166.2	138.5	0	0	111	E537 C541	E537-E539 PolarHBondContact O-N 3.27Å; E539-C541 PolarHBondContact O-N 3.15Å
540	T	31.5	Very low	33.2	Very low	139 Å²	139	146.3 Å²	146.3	85%	0.853	84%	0.84	S	S	*	*			trans	-69.1	116.2	174	41.2	0	0	0	0	111.1	P538	P538-T540 PolarHBondContact O-N 2.98Å
541	C	29.9	Very low	33	Very low	134 Å²	134	145.1 Å²	145.1	91%	0.905	85%	0.846	S	S	*	*			trans	-90	114.2	174	-153.8	0	0	0	0	110.5	E539	E539-C541 PolarHBondContact O-N 3.15Å
542	E	29.9	Very low	33	Very low	148 Å²	148	151.4 Å²	151.4	69%	0.692	86%	0.861	S	S	*	*			trans	-105.5	141.6	177.2	-144	-162.9	-134	0	0	110.7
543	R	31.4	Very low	32.7	Very low	213 Å²	213	157.1 Å²	157.1	80%	0.804	88%	0.875	S	S	*	*			trans	76.1	144.4	171.4	-49.6	173.5	-169.4	-165.3	-1.7	116.3
544	S	32.3	Very low	32.4	Very low	193 Å²	193	154.3 Å²	154.3	100%	1.35	88%	0.875	S	S	*	*			cis	-129.9	0	4.4	-54	0	0	0	0	111.7

Retrieved 544 of 544 residues in 704.1 ms (Link to these results)

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