A0A093I596_STRCA Loading...

Major facilitator superfamily domain-containing protein 10

Probable organic anion transporter which may serve as a transporter for some non-steroidal anti-inflammatory drugs (NSAIDs) as well as other organic anions across the luminal membranes of renal proximal tubules at the final excretion step into the urine.

AlphaFold DB , UniProt , Accession A0A093I596, Species STRCA (Struthio camelus australis), Gene n/a, Length 461 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M49.4Very low47.3Very low198 Ų198117.1 Ų117.198%0.97563%0.63SS**  0-51.20-121.3158.4169.700111.5L3 R4 E5M1-L3 PolarHBondContact O-N 3.27Å; M1-R4 PolarHBondContact O-N 3.5Å; M1-R4 VanDerWaalsContact O-N 3.1Å; M1-E5 PolarHBondContact O-N 3.12Å; M1-E5 VanDerWaalsContact O-N 3.08Å
2A48.7Very low48.5Very low79 Ų79110.7 Ų110.765%0.65360%0.601SS**Hα-helixtrans-56.7-35.5177.900000116.2E5 G6A2-E5 PolarHBondContact O-N 3.1Å; A2-G6 PolarHBondContact O-N 3.15Å
3L43.9Very low49.7Very low154 Ų154107.6 Ų107.681%0.80659%0.588SS**Hα-helixtrans-69.5-35.5175.5-73.3167.3000112.9M1 E7M1-L3 PolarHBondContact O-N 3.27Å; L3-E7 PolarHBondContact O-N 3.04Å; L3-E7 VanDerWaalsContact O-N 3.15Å
4R41Very low50.6Low200 Ų200107.1 Ų107.176%0.75558%0.584SS**Hα-helixtrans-73.3-32175.6-99.2-177.8173.4178.9-2112.3M1 N8M1-R4 PolarHBondContact O-N 3.5Å; M1-R4 VanDerWaalsContact O-N 3.1Å; R4-N8 WeakPolarHBondContact O-CB 3.44Å; R4-N8 PolarHBondContact O-N 3.08Å; R4-N8 VanDerWaalsContact O-N 3.12Å
5E41.1Very low51.7Low131 Ų131106.6 Ų106.661%0.61258%0.581SS**Hα-helixtrans-72.8-37.3174.3-75.8178.4158.300112.2M1 A2 N9M1-E5 PolarHBondContact O-N 3.12Å; M1-E5 VanDerWaalsContact O-N 3.08Å; A2-E5 PolarHBondContact O-N 3.1Å; E5-N9 WeakPolarHBondContact O-CB 3.42Å; E5-N9 PolarHBondContact O-N 3.49Å
6G43.3Very low52.8Low43 Ų43109.3 Ų109.344%0.44359%0.585SS.*Hα-helixtrans-64-42172.700000113.3A2 N9 S10A2-G6 PolarHBondContact O-N 3.15Å; G6-N9 PolarHBondContact O-N 3Å; G6-S10 WeakPolarHBondContact O-CB 3.47Å; G6-S10 PolarHBondContact O-N 3.26Å; G6-S10 PolarHBondContact O-OG 2.81Å
7E44Very low53.8Low134 Ų134108.6 Ų108.663%0.62658%0.578SS**Hα-helixtrans-65.1-45.1174.9-77.8-178.915400112.2L3 N9 S10 S11L3-E7 PolarHBondContact O-N 3.04Å; L3-E7 VanDerWaalsContact O-N 3.15Å; E7-N9 PolarHBondContact O-N 3.29Å; E7-S10 PolarHBondContact O-N 3.45Å; E7-S10 PolarHBondContact O-OG 2.98Å; E7-S11 PolarHBondContact O-N 3.41Å; E7-S11 PolarHBondContact O-OG 2.89Å
8N45.8Very low54.9Low119 Ų119107.8 Ų107.864%0.63657%0.57SS**Hα-helixtrans-65.3-34176.9-94.1-6.1000113.5R4 S11 S12R4-N8 WeakPolarHBondContact O-CB 3.44Å; R4-N8 PolarHBondContact O-N 3.08Å; R4-N8 VanDerWaalsContact O-N 3.12Å; N8-S11 WeakPolarHBondContact CA-OG 3.45Å; N8-S11 PolarHBondContact O-OG 3.21Å; N8-S12 WeakPolarHBondContact O-CB 3.5Å; N8-S12 PolarHBondContact O-N 3.03Å; N8-S12 PolarHBondContact O-OG 3.14Å
9N50.3Low55.9Low113 Ų113109.7 Ų109.760%0.60458%0.575SS**Hα-helixtrans-71.2-41.1174.9-118.1-5.6000111.1E5 G6 E7 S12 V13E5-N9 WeakPolarHBondContact O-CB 3.42Å; E5-N9 PolarHBondContact O-N 3.49Å; G6-N9 PolarHBondContact O-N 3Å; E7-N9 PolarHBondContact O-N 3.29Å; N9-S12 PolarHBondContact O-N 2.98Å; N9-S12 PolarHBondContact O-OG 3.41Å; N9-V13 VanDerWaalsContact O-CG2 3.3Å; N9-V13 WeakPolarHBondContact O-CG2 3.33Å; N9-V13 PolarHBondContact O-N 3.16Å; N9-V13 VanDerWaalsContact O-N 3.1Å
10S54.7Low57.3Low65 Ų65107.8 Ų107.846%0.45557%0.571SS.*Hα-helixtrans-66.1-37.9178.775.10000113.4G6 E7 N14G6-S10 WeakPolarHBondContact O-CB 3.47Å; G6-S10 PolarHBondContact O-N 3.26Å; G6-S10 PolarHBondContact O-OG 2.81Å; E7-S10 PolarHBondContact O-N 3.45Å; E7-S10 PolarHBondContact O-OG 2.98Å; S10-N14 WeakPolarHBondContact O-CB 3.41Å; S10-N14 PolarHBondContact O-N 3.47Å; S10-N14 VanDerWaalsContact O-N 3.14Å
11S58.4Low58.7Low52 Ų52102.9 Ų102.936%0.36455%0.547SS..Hα-helixtrans-67-43.8174.960.40000111.4E7 N8 V13 N14 D15E7-S11 PolarHBondContact O-N 3.41Å; E7-S11 PolarHBondContact O-OG 2.89Å; N8-S11 WeakPolarHBondContact CA-OG 3.45Å; N8-S11 PolarHBondContact O-OG 3.21Å; S11-V13 VanDerWaalsContact C-N 3.33Å; S11-V13 PolarHBondContact O-N 2.93Å; S11-N14 PolarHBondContact O-N 3.3Å; S11-D15 WeakPolarHBondContact O-CB 3.3Å; S11-D15 PolarHBondContact O-N 3.36Å
12S61.8Low60.7Low40 Ų4096 Ų9628%0.2851%0.514SS..Hα-helixtrans-64.8-32.8178.879.80000113.9N8 N9 K16N8-S12 WeakPolarHBondContact O-CB 3.5Å; N8-S12 PolarHBondContact O-N 3.03Å; N8-S12 PolarHBondContact O-OG 3.14Å; N9-S12 PolarHBondContact O-N 2.98Å; N9-S12 PolarHBondContact O-OG 3.41Å; S12-K16 WeakPolarHBondContact O-CG 3.5Å; S12-K16 PolarHBondContact O-N 3.1Å; S12-K16 VanDerWaalsContact O-N 3.16Å
13V63.4Low62.9Low71 Ų71100.1 Ų100.143%0.4351%0.513SS..Hα-helixtrans-73.9-42.3176.4172.20000110.9N9 S11 K16 Q17N9-V13 VanDerWaalsContact O-CG2 3.3Å; N9-V13 WeakPolarHBondContact O-CG2 3.33Å; N9-V13 PolarHBondContact O-N 3.16Å; N9-V13 VanDerWaalsContact O-N 3.1Å; S11-V13 VanDerWaalsContact C-N 3.33Å; S11-V13 PolarHBondContact O-N 2.93Å; V13-K16 PolarHBondContact O-N 3.41Å; V13-Q17 WeakPolarHBondContact O-CG 3.32Å; V13-Q17 PolarHBondContact O-N 3Å
14N62.8Low65.4Low100 Ų10093.1 Ų93.154%0.53548%0.476SS..Hα-helixtrans-63-41.3175.2-83.2-23.4000111.8S10 S11 Q17 E18S10-N14 WeakPolarHBondContact O-CB 3.41Å; S10-N14 PolarHBondContact O-N 3.47Å; S10-N14 VanDerWaalsContact O-N 3.14Å; S11-N14 PolarHBondContact O-N 3.3Å; N14-Q17 PolarHBondContact O-N 3.22Å; N14-E18 WeakPolarHBondContact O-CB 3.48Å; N14-E18 PolarHBondContact O-N 3.38Å
15D66.7Low68Low100 Ų10083.8 Ų83.854%0.53544%0.441SS..Hα-helixtrans-64.1-43.4177.1-78-20.7000112S11 Q17 E18 Q19S11-D15 WeakPolarHBondContact O-CB 3.3Å; S11-D15 PolarHBondContact O-N 3.36Å; D15-Q17 VanDerWaalsContact C-N 3.35Å; D15-Q17 PolarHBondContact O-N 3.06Å; D15-E18 PolarHBondContact O-N 2.99Å; D15-Q19 VanDerWaalsContact O-CB 3.32Å; D15-Q19 WeakPolarHBondContact O-CB 3.43Å; D15-Q19 PolarHBondContact O-N 2.96Å
16K68.9Low70.7Confident149 Ų14981.2 Ų81.265%0.64843%0.434SS*.Hα-helixtrans-63.1-39.5175.4-76.4176.9-178.3176.30112.2S12 V13 S20S12-K16 WeakPolarHBondContact O-CG 3.5Å; S12-K16 PolarHBondContact O-N 3.1Å; S12-K16 VanDerWaalsContact O-N 3.16Å; V13-K16 PolarHBondContact O-N 3.41Å; K16-S20 VanDerWaalsContact O-CB 3.3Å; K16-S20 WeakPolarHBondContact O-CB 3.5Å; K16-S20 PolarHBondContact O-N 3.46Å
17Q70.8Confident73.3Confident99 Ų9979.7 Ų79.746%0.46342%0.416SS..Hα-helixtrans-68.4-40.4176.1-75.7-176.1-1.800112.3V13 N14 D15 G21V13-Q17 WeakPolarHBondContact O-CG 3.32Å; V13-Q17 PolarHBondContact O-N 3Å; N14-Q17 PolarHBondContact O-N 3.22Å; D15-Q17 VanDerWaalsContact C-N 3.35Å; D15-Q17 PolarHBondContact O-N 3.06Å; Q17-G21 PolarHBondContact O-N 3.31Å
18E72.9Confident75.8Confident93 Ų9373.5 Ų73.544%0.43539%0.387SS..Hα-helixtrans-68.8-38.4177.6-165166.7-166.300111.4N14 D15 G21 N22 K171N14-E18 WeakPolarHBondContact O-CB 3.48Å; N14-E18 PolarHBondContact O-N 3.38Å; D15-E18 PolarHBondContact O-N 2.99Å; E18-G21 PolarHBondContact O-N 2.9Å; E18-N22 WeakPolarHBondContact O-CB 3.3Å; E18-N22 VanDerWaalsContact O-CG 3.28Å; E18-N22 PolarHBondContact O-N 3.42Å; E18-N22 PolarHBondContact O-ND2 2.72Å; E18-K171 IonicContact OE1-NZ 3Å; E18-K171 PolarHBondContact OE1-NZ 3.21Å
19Q74.4Confident78.3Confident144 Ų14469.2 Ų69.267%0.67336%0.363SS*.Hα-helixtrans-66.2-43.1175.3-162.8176.517.100112D15 N22 R23D15-Q19 VanDerWaalsContact O-CB 3.32Å; D15-Q19 WeakPolarHBondContact O-CB 3.43Å; D15-Q19 PolarHBondContact O-N 2.96Å; Q19-N22 PolarHBondContact O-N 3.35Å; Q19-R23 PolarHBondContact O-N 2.89Å
20S82.8Confident80.6Confident71 Ų7167 Ų6750%0.49735%0.351SS..Hα-helixtrans-61.1-45.6173.6-176.60000111.8K16 N22 R23 V24K16-S20 VanDerWaalsContact O-CB 3.3Å; K16-S20 WeakPolarHBondContact O-CB 3.5Å; K16-S20 PolarHBondContact O-N 3.46Å; S20-N22 PolarHBondContact O-N 3.28Å; S20-R23 WeakPolarHBondContact O-CB 3.3Å; S20-R23 PolarHBondContact O-N 3.03Å; S20-V24 PolarHBondContact O-N 3.18Å
21G87.6Confident82.6Confident6 Ų664.2 Ų64.26%0.06233%0.331CS..Hα-helixtrans-60.8-41.9176.500000113Q17 E18 R23 V24 I25Q17-G21 PolarHBondContact O-N 3.31Å; E18-G21 PolarHBondContact O-N 2.9Å; G21-R23 VanDerWaalsContact C-N 3.32Å; G21-R23 PolarHBondContact O-N 2.81Å; G21-V24 PolarHBondContact O-N 3Å; G21-I25 WeakPolarHBondContact O-CD1 3.33Å; G21-I25 VanDerWaalsContact O-CG1 3.24Å; G21-I25 WeakPolarHBondContact O-CG1 3.22Å; G21-I25 PolarHBondContact O-N 2.71Å
22N91.5Very high84.4Confident52 Ų5261.8 Ų61.828%0.27832%0.315SS..Hα-helixtrans-63.9-36.7175.8-74.5-33.3000112.8E18 Q19 S20 T26 K175E18-N22 WeakPolarHBondContact O-CB 3.3Å; E18-N22 VanDerWaalsContact O-CG 3.28Å; E18-N22 PolarHBondContact O-N 3.42Å; E18-N22 PolarHBondContact O-ND2 2.72Å; Q19-N22 PolarHBondContact O-N 3.35Å; S20-N22 PolarHBondContact O-N 3.28Å; N22-T26 PolarHBondContact O-N 3.41Å; N22-T26 VanDerWaalsContact O-N 3.09Å; N22-T26 PolarHBondContact O-OG1 3.04Å; N22-K175 PolarHBondContact OD1-NZ 2.89Å
23R94.5Very high86.1Confident167 Ų16761.3 Ų61.363%0.6331%0.308SS*.Hα-helixtrans-63.7-48.3174.9-174.3179.2177.5178.4-0111Q19 S20 G21 I25 T26 I27Q19-R23 PolarHBondContact O-N 2.89Å; S20-R23 WeakPolarHBondContact O-CB 3.3Å; S20-R23 PolarHBondContact O-N 3.03Å; G21-R23 VanDerWaalsContact C-N 3.32Å; G21-R23 PolarHBondContact O-N 2.81Å; R23-I25 PolarHBondContact O-N 2.97Å; R23-T26 PolarHBondContact O-N 3.35Å; R23-I27 HydrophobicContact CG-CD1 3.85Å; R23-I27 WeakPolarHBondContact O-CD1 3.24Å; R23-I27 WeakPolarHBondContact O-CG1 3.46Å; R23-I27 PolarHBondContact O-N 3.44Å
24V96Very high87.8Confident6 Ų659.7 Ų59.74%0.03630%0.297CS..Hα-helixtrans-59.9-45.6177.2175.30000111.3S20 G21 T26 I27 V28 I163 L167 P232 T234S20-V24 PolarHBondContact O-N 3.18Å; G21-V24 PolarHBondContact O-N 3Å; V24-T26 VanDerWaalsContact C-N 3.27Å; V24-T26 PolarHBondContact O-N 2.94Å; V24-I27 PolarHBondContact O-N 3.09Å; V24-V28 HydrophobicContact CG1-CG2 4.22Å; V24-V28 WeakPolarHBondContact O-CG2 3.47Å; V24-V28 PolarHBondContact O-N 3.42Å; V24-I163 HydrophobicContact CG1-CG2 3.65Å; V24-L167 HydrophobicContact CB-CD2 4.28Å; V24-L167 HydrophobicContact CG1-CD2 4.27Å; V24-P232 HydrophobicContact CG2-CG 3.84Å; V24-T234 HydrophobicContact CG1-CG2 4.19Å
25I96.8Very high89.4Confident5 Ų555 Ų553%0.02627%0.272CS..Hα-helixtrans-56.4-43.4176.9-69163.4000111.3G21 R23 F29 I164 L167 A172 K175 M179G21-I25 WeakPolarHBondContact O-CD1 3.33Å; G21-I25 VanDerWaalsContact O-CG1 3.24Å; G21-I25 WeakPolarHBondContact O-CG1 3.22Å; G21-I25 PolarHBondContact O-N 2.71Å; R23-I25 PolarHBondContact O-N 2.97Å; I25-F29 VanDerWaalsContact O-CB 3.26Å; I25-F29 WeakPolarHBondContact O-CB 3.37Å; I25-F29 PolarHBondContact O-N 2.81Å; I25-I164 HydrophobicContact CB-CD1 4.44Å; I25-I164 HydrophobicContact CG1-CD1 3.88Å; I25-L167 HydrophobicContact CD1-CD1 3.94Å; I25-L167 HydrophobicContact CG1-CD1 3.68Å; I25-A172 HydrophobicContact CD1-CB 4.38Å; I25-A172 WeakPolarHBondContact CD1-O 3.43Å; I25-K175 HydrophobicContact CD1-CD 4.31Å; I25-K175 HydrophobicContact CD1-CG 4.24Å; I25-M179 HydrophobicContact CG2-CB 4.04Å; I25-M179 HydrophobicContact CG2-CG 3.82Å
26T97Very high90.8Very high76 Ų7650.3 Ų50.347%0.46625%0.247SC..Hα-helixtrans-68.1-42.3-178.4-53.90000111.5N22 R23 V24 F29 L30N22-T26 PolarHBondContact O-N 3.41Å; N22-T26 VanDerWaalsContact O-N 3.09Å; N22-T26 PolarHBondContact O-OG1 3.04Å; R23-T26 PolarHBondContact O-N 3.35Å; V24-T26 VanDerWaalsContact C-N 3.27Å; V24-T26 PolarHBondContact O-N 2.94Å; T26-F29 PolarHBondContact O-N 2.82Å; T26-L30 HydrophobicContact CG2-CD1 4.17Å; T26-L30 WeakPolarHBondContact O-CG 3.43Å; T26-L30 PolarHBondContact O-N 3.34Å
27I97.5Very high92.1Very high12 Ų1244.4 Ų44.46%0.06222%0.222CC..Hα-helixtrans-62.6-49.6176.5-66159000110.2R23 V24 F29 L30 A31 F226 L230 L231R23-I27 HydrophobicContact CG-CD1 3.85Å; R23-I27 WeakPolarHBondContact O-CD1 3.24Å; R23-I27 WeakPolarHBondContact O-CG1 3.46Å; R23-I27 PolarHBondContact O-N 3.44Å; V24-I27 PolarHBondContact O-N 3.09Å; I27-F29 VanDerWaalsContact C-N 3.31Å; I27-F29 PolarHBondContact O-N 2.88Å; I27-L30 PolarHBondContact O-N 2.97Å; I27-A31 VanDerWaalsContact O-CB 3.31Å; I27-A31 WeakPolarHBondContact O-CB 3.43Å; I27-A31 PolarHBondContact O-N 3Å; I27-F226 HydrophobicContact CB-CE1 4.47Å; I27-F226 HydrophobicContact CG2-CE1 3.8Å; I27-F226 HydrophobicContact CG2-CZ 4.41Å; I27-F226 WeakPolarHBondContact O-CE1 3.06Å; I27-L230 HydrophobicContact CD1-CB 4.49Å; I27-L230 VanDerWaalsContact CD1-O 3.3Å; I27-L230 WeakPolarHBondContact CD1-O 3.44Å; I27-L230 HydrophobicContact CG1-CB 4.47Å; I27-L230 HydrophobicContact CG2-CB 4.42Å; I27-L231 HydrophobicContact CG2-CB 4.14Å; I27-L231 HydrophobicContact CG2-CD1 3.83Å
28V97.4Very high93.3Very high3 Ų339.7 Ų39.72%0.01820%0.201CC..Hα-helixtrans-61.1-41.4178.8173.50000111.3V24 L32 I163 I164 I180 L231V24-V28 HydrophobicContact CG1-CG2 4.22Å; V24-V28 WeakPolarHBondContact O-CG2 3.47Å; V24-V28 PolarHBondContact O-N 3.42Å; V28-L32 WeakPolarHBondContact O-CB 3.38Å; V28-L32 PolarHBondContact O-N 3.07Å; V28-I163 HydrophobicContact CG2-CB 4.26Å; V28-I163 HydrophobicContact CG2-CG2 3.58Å; V28-I164 HydrophobicContact CB-CD1 4.18Å; V28-I164 HydrophobicContact CG1-CD1 4.25Å; V28-I164 HydrophobicContact CG1-CG1 4.22Å; V28-I164 HydrophobicContact CG2-CD1 4.26Å; V28-I180 HydrophobicContact CG1-CD1 4.37Å; V28-I180 HydrophobicContact CG1-CG1 4.35Å; V28-L231 HydrophobicContact CG2-CD1 4.14Å
29F97.7Very high94.4Very high30 Ų3036.6 Ų36.613%0.13219%0.186CC..Hα-helixtrans-59-50175.6165.3-103.2000112.3I25 T26 I27 L33 M179 V182 A183 L186I25-F29 VanDerWaalsContact O-CB 3.26Å; I25-F29 WeakPolarHBondContact O-CB 3.37Å; I25-F29 PolarHBondContact O-N 2.81Å; T26-F29 PolarHBondContact O-N 2.82Å; I27-F29 VanDerWaalsContact C-N 3.31Å; I27-F29 PolarHBondContact O-N 2.88Å; F29-L33 HydrophobicContact CE1-CD2 4.38Å; F29-L33 HydrophobicContact CZ-CD2 4.05Å; F29-L33 VanDerWaalsContact O-CB 3.28Å; F29-L33 WeakPolarHBondContact O-CB 3.49Å; F29-L33 PolarHBondContact O-N 2.99Å; F29-M179 HydrophobicContact CB-CB 4.44Å; F29-M179 HydrophobicContact CB-CE 4.44Å; F29-M179 HydrophobicContact CD1-CE 4.15Å; F29-M179 HydrophobicContact CD2-CB 4.41Å; F29-M179 HydrophobicContact CD2-CE 3.7Å; F29-M179 WeakPolarHBondContact CD2-O 3.34Å; F29-M179 HydrophobicContact CE1-CE 4.37Å; F29-M179 HydrophobicContact CE2-CE 3.93Å; F29-M179 HydrophobicContact CG-CE 3.81Å; F29-M179 HydrophobicContact CZ-CE 4.26Å; F29-V182 HydrophobicContact CE2-CB 4.11Å; F29-V182 HydrophobicContact CE2-CG1 3.9Å; F29-V182 HydrophobicContact CZ-CG1 4.42Å; F29-A183 HydrophobicContact CD2-CB 3.81Å; F29-A183 HydrophobicContact CE2-CB 3.97Å; F29-L186 HydrophobicContact CZ-CD1 4.36Å
30L97.9Very high95.4Very high67 Ų6729.8 Ų29.835%0.35115%0.154SC..Hα-helixtrans-67-46.1-178.1-71.8172.9000111.9T26 I27 L32 L33 I34 F226T26-L30 HydrophobicContact CG2-CD1 4.17Å; T26-L30 WeakPolarHBondContact O-CG 3.43Å; T26-L30 PolarHBondContact O-N 3.34Å; I27-L30 PolarHBondContact O-N 2.97Å; L30-L32 PolarHBondContact O-N 3.18Å; L30-L33 PolarHBondContact O-N 3.42Å; L30-I34 VanDerWaalsContact O-CG1 3.3Å; L30-I34 WeakPolarHBondContact O-CG1 3.33Å; L30-I34 PolarHBondContact O-N 3.41Å; L30-F226 HydrophobicContact CB-CE1 3.92Å; L30-F226 HydrophobicContact CB-CE2 4.42Å; L30-F226 HydrophobicContact CB-CZ 3.65Å; L30-F226 HydrophobicContact CD1-CE2 4.29Å; L30-F226 HydrophobicContact CD1-CZ 3.85Å; L30-F226 HydrophobicContact CG-CZ 4.41Å
31A97.5Very high95.9Very high5 Ų526.4 Ų26.44%0.04113%0.13CC..Hα-helixtrans-56.5-51.4176.700000111I27 L33 I34 D35 D223 F226 I227I27-A31 VanDerWaalsContact O-CB 3.31Å; I27-A31 WeakPolarHBondContact O-CB 3.43Å; I27-A31 PolarHBondContact O-N 3Å; A31-L33 VanDerWaalsContact C-N 3.32Å; A31-L33 PolarHBondContact O-N 3.21Å; A31-I34 PolarHBondContact O-N 2.71Å; A31-D35 PolarHBondContact O-N 2.94Å; A31-D223 WeakPolarHBondContact CA-OD1 3.37Å; A31-D223 VanDerWaalsContact CB-OD1 3.26Å; A31-D223 WeakPolarHBondContact CB-OD1 3.38Å; A31-D223 VanDerWaalsContact O-OD1 3.14Å; A31-F226 HydrophobicContact CB-CD1 3.96Å; A31-F226 HydrophobicContact CB-CE1 4.06Å; A31-I227 HydrophobicContact CB-CD1 4.05Å; A31-I227 HydrophobicContact CB-CG1 3.78Å
32L97.1Very high96.2Very high2 Ų226.1 Ų26.11%0.0113%0.127CC..Hα-helixtrans-64.1-37.2178.9-169.266.4000112.3V28 L30 D35 L36 V157 I180 A183 F184V28-L32 WeakPolarHBondContact O-CB 3.38Å; V28-L32 PolarHBondContact O-N 3.07Å; L30-L32 PolarHBondContact O-N 3.18Å; L32-D35 PolarHBondContact O-N 3.3Å; L32-L36 HydrophobicContact CD1-CD1 4.3Å; L32-L36 HydrophobicContact CD1-CG 4.31Å; L32-L36 HydrophobicContact CD2-CD1 4.32Å; L32-L36 HydrophobicContact CG-CD1 3.77Å; L32-L36 HydrophobicContact CG-CG 4.2Å; L32-L36 VanDerWaalsContact O-CB 3.27Å; L32-L36 WeakPolarHBondContact O-CB 3.36Å; L32-L36 WeakPolarHBondContact O-CD1 3.44Å; L32-L36 WeakPolarHBondContact O-CG 3.49Å; L32-L36 PolarHBondContact O-N 3.46Å; L32-V157 HydrophobicContact CD1-CG2 4.1Å; L32-I180 HydrophobicContact CD2-CB 4.21Å; L32-I180 HydrophobicContact CD2-CG1 4.08Å; L32-I180 HydrophobicContact CD2-CG2 3.72Å; L32-A183 HydrophobicContact CB-CB 4.32Å; L32-A183 HydrophobicContact CD2-CB 4.17Å; L32-A183 HydrophobicContact CG-CB 4.29Å; L32-F184 HydrophobicContact CD2-CD2 4.27Å; L32-F184 HydrophobicContact CD2-CE2 3.92Å
33L97.7Very high96Very high29 Ų2926.3 Ų26.315%0.15213%0.128CC..Hα-helixtrans-62.5-44.4175.9178.961.2000111.5F29 L30 A31 L36 L37 A183 L186F29-L33 HydrophobicContact CE1-CD2 4.38Å; F29-L33 HydrophobicContact CZ-CD2 4.05Å; F29-L33 VanDerWaalsContact O-CB 3.28Å; F29-L33 WeakPolarHBondContact O-CB 3.49Å; F29-L33 PolarHBondContact O-N 2.99Å; L30-L33 PolarHBondContact O-N 3.42Å; A31-L33 VanDerWaalsContact C-N 3.32Å; A31-L33 PolarHBondContact O-N 3.21Å; L33-L36 PolarHBondContact O-N 2.74Å; L33-L37 HydrophobicContact CD1-CD1 4.4Å; L33-L37 HydrophobicContact CD1-CG 4.29Å; L33-L37 HydrophobicContact CG-CD1 4.2Å; L33-L37 WeakPolarHBondContact O-CB 3.47Å; L33-L37 VanDerWaalsContact O-CG 3.25Å; L33-L37 WeakPolarHBondContact O-CG 3.34Å; L33-L37 PolarHBondContact O-N 3.07Å; L33-A183 HydrophobicContact CB-CB 4.22Å; L33-L186 HydrophobicContact CD1-CB 3.73Å
34I97.5Very high95.7Very high37 Ų3720.7 Ų20.719%0.1911%0.113CC..Hα-helixtrans-61.7-47.6177.5-63.8164.2000110.3L30 A31 L36 L37 G38 F219 D223L30-I34 VanDerWaalsContact O-CG1 3.3Å; L30-I34 WeakPolarHBondContact O-CG1 3.33Å; L30-I34 PolarHBondContact O-N 3.41Å; A31-I34 PolarHBondContact O-N 2.71Å; I34-L36 VanDerWaalsContact C-N 3.33Å; I34-L36 PolarHBondContact O-N 3.46Å; I34-L37 PolarHBondContact O-N 2.94Å; I34-G38 PolarHBondContact O-N 3.31Å; I34-G38 VanDerWaalsContact O-N 3.1Å; I34-F219 HydrophobicContact CG2-CB 3.85Å; I34-F219 HydrophobicContact CG2-CD1 4.22Å; I34-F219 HydrophobicContact CG2-CG 4.33Å; I34-F219 WeakPolarHBondContact CG2-O 3.33Å; I34-D223 HydrophobicContact CB-CB 4.29Å; I34-D223 HydrophobicContact CG2-CB 3.86Å
35D97.3Very high95.4Very high2 Ų220.6 Ų20.61%0.01111%0.113CC..Hα-helixtrans-57.8-44.6176.2171.155.4000112.6A31 L32 G38 F39 L127 K154 N156A31-D35 PolarHBondContact O-N 2.94Å; L32-D35 PolarHBondContact O-N 3.3Å; D35-G38 PolarHBondContact O-N 3.32Å; D35-F39 WeakPolarHBondContact O-CB 3.38Å; D35-F39 PolarHBondContact O-N 2.83Å; D35-L127 WeakPolarHBondContact OD1-CD1 3.27Å; D35-K154 IonicContact OD1-NZ 2.96Å; D35-K154 PolarHBondContact OD1-NZ 2.89Å; D35-K154 WeakPolarHBondContact OD2-CE 3.24Å; D35-K154 IonicContact OD2-NZ 3.24Å; D35-K154 PolarHBondContact OD2-NZ 2.98Å; D35-N156 PolarHBondContact OD2-ND2 2.88Å
36L96.7Very high94.8Very high2 Ų221.8 Ų21.81%0.0112%0.117CC..Hα-helixtrans-72.5-34.1-177-70.3174.6000112.7L32 L33 I34 F39 A40 A183 F184 F188L32-L36 HydrophobicContact CD1-CD1 4.3Å; L32-L36 HydrophobicContact CD1-CG 4.31Å; L32-L36 HydrophobicContact CD2-CD1 4.32Å; L32-L36 HydrophobicContact CG-CD1 3.77Å; L32-L36 HydrophobicContact CG-CG 4.2Å; L32-L36 VanDerWaalsContact O-CB 3.27Å; L32-L36 WeakPolarHBondContact O-CB 3.36Å; L32-L36 WeakPolarHBondContact O-CD1 3.44Å; L32-L36 WeakPolarHBondContact O-CG 3.49Å; L32-L36 PolarHBondContact O-N 3.46Å; L33-L36 PolarHBondContact O-N 2.74Å; I34-L36 VanDerWaalsContact C-N 3.33Å; I34-L36 PolarHBondContact O-N 3.46Å; L36-F39 PolarHBondContact O-N 3.01Å; L36-A40 WeakPolarHBondContact O-CB 3.48Å; L36-A40 PolarHBondContact O-N 3.12Å; L36-A183 HydrophobicContact CD1-CB 4.25Å; L36-F184 HydrophobicContact CD1-CB 4.33Å; L36-F184 HydrophobicContact CD1-CD1 3.89Å; L36-F184 HydrophobicContact CD1-CD2 3.94Å; L36-F184 HydrophobicContact CD1-CE1 4.06Å; L36-F184 HydrophobicContact CD1-CE2 4.12Å; L36-F184 HydrophobicContact CD1-CG 3.8Å; L36-F184 HydrophobicContact CD1-CZ 4.15Å; L36-F184 HydrophobicContact CD2-CD1 4.06Å; L36-F184 HydrophobicContact CD2-CE1 3.63Å; L36-F184 HydrophobicContact CD2-CZ 4Å; L36-F188 HydrophobicContact CD2-CE2 3.92Å
37L96.4Very high94.1Very high24 Ų2420.4 Ų20.413%0.12611%0.11CC..Hα-helixtrans-58.9-51169.2-74.5169.7000109.9L33 I34 F39 A40 L41 L190 F219L33-L37 HydrophobicContact CD1-CD1 4.4Å; L33-L37 HydrophobicContact CD1-CG 4.29Å; L33-L37 HydrophobicContact CG-CD1 4.2Å; L33-L37 WeakPolarHBondContact O-CB 3.47Å; L33-L37 VanDerWaalsContact O-CG 3.25Å; L33-L37 WeakPolarHBondContact O-CG 3.34Å; L33-L37 PolarHBondContact O-N 3.07Å; I34-L37 PolarHBondContact O-N 2.94Å; L37-F39 VanDerWaalsContact C-N 3.34Å; L37-F39 PolarHBondContact O-N 3.23Å; L37-A40 PolarHBondContact O-N 3.44Å; L37-L41 WeakPolarHBondContact O-CG 3.37Å; L37-L41 PolarHBondContact O-N 3.2Å; L37-L190 HydrophobicContact CD2-CB 3.73Å; L37-F219 HydrophobicContact CB-CD2 4.09Å; L37-F219 HydrophobicContact CB-CE2 3.97Å
38G95.8Very high93.5Very high1 Ų122.5 Ų22.51%0.0113%0.126CC..Hα-helixtrans-57.8-44177.400000113.3I34 D35 A216I34-G38 PolarHBondContact O-N 3.31Å; I34-G38 VanDerWaalsContact O-N 3.1Å; D35-G38 PolarHBondContact O-N 3.32Å; G38-A216 WeakPolarHBondContact O-CB 3.26Å
39F95.1Very high93.1Very high28 Ų2822.4 Ų22.412%0.12313%0.125CC..Hα-helixtrans-66.2-42.1178.1174.7-101000112.8D35 L36 L37 L41 I42 L43 F96 Y131 F188D35-F39 WeakPolarHBondContact O-CB 3.38Å; D35-F39 PolarHBondContact O-N 2.83Å; L36-F39 PolarHBondContact O-N 3.01Å; L37-F39 VanDerWaalsContact C-N 3.34Å; L37-F39 PolarHBondContact O-N 3.23Å; F39-L41 VanDerWaalsContact C-N 3.31Å; F39-L41 PolarHBondContact O-N 2.99Å; F39-I42 WeakPolarHBondContact O-CG2 3.35Å; F39-L43 HydrophobicContact CE1-CD2 4.44Å; F39-F96 HydrophobicContact CD2-CE1 4.38Å; F39-F96 HydrophobicContact CD2-CZ 4.11Å; F39-F96 HydrophobicContact CE2-CD1 4.17Å; F39-F96 AromaticContact CE2-CE1 3.37Å; F39-F96 HydrophobicContact CE2-CE1 3.37Å; F39-F96 HydrophobicContact CE2-CE2 4.09Å; F39-F96 AromaticContact CE2-CZ 3.36Å; F39-F96 HydrophobicContact CE2-CZ 3.36Å; F39-F96 HydrophobicContact CZ-CD1 4.13Å; F39-F96 AromaticContact CZ-CE1 3.59Å; F39-F96 HydrophobicContact CZ-CE1 3.59Å; F39-F96 HydrophobicContact CZ-CZ 4.08Å; F39-Y131 VanDerWaalsContact CA-OH 3.23Å; F39-Y131 WeakPolarHBondContact CA-OH 3.36Å; F39-Y131 PolarHBondContact N-OH 2.88Å; F39-F188 HydrophobicContact CD1-CE1 4.43Å; F39-F188 AromaticContact CD1-CZ 3.93Å; F39-F188 HydrophobicContact CD1-CZ 3.93Å; F39-F188 HydrophobicContact CE1-CE1 4.05Å; F39-F188 AromaticContact CE1-CZ 3.71Å; F39-F188 HydrophobicContact CE1-CZ 3.71Å
40A94.8Very high92.4Very high0 Ų021.1 Ų21.10%012%0.12CC..Hα-helixtrans-79-13.3-171.300000113.7L36 L37 I42 L43 G187 P192L36-A40 WeakPolarHBondContact O-CB 3.48Å; L36-A40 PolarHBondContact O-N 3.12Å; L37-A40 PolarHBondContact O-N 3.44Å; A40-I42 PolarHBondContact O-N 3Å; A40-L43 HydrophobicContact CB-CD1 3.94Å; A40-L43 PolarHBondContact O-N 2.8Å; A40-G187 WeakPolarHBondContact CB-O 3.47Å; A40-P192 HydrophobicContact CB-CG 4.24Å
41L95.1Very high91.6Very high0 Ų019.8 Ų19.80%011%0.113CC..THydrogen-bonded Turntrans-54.4-33.5173.6-74.1167.6000113.2L37 F39 L45 G191 I194 G195 L215 A216 F219L37-L41 WeakPolarHBondContact O-CG 3.37Å; L37-L41 PolarHBondContact O-N 3.2Å; F39-L41 VanDerWaalsContact C-N 3.31Å; F39-L41 PolarHBondContact O-N 2.99Å; L41-L45 WeakPolarHBondContact O-CD1 3.29Å; L41-G191 WeakPolarHBondContact CD2-O 3.47Å; L41-I194 HydrophobicContact CD2-CB 3.7Å; L41-I194 HydrophobicContact CD2-CG2 3.57Å; L41-G195 VanDerWaalsContact CD2-N 3.35Å; L41-G195 WeakPolarHBondContact O-CA 3.5Å; L41-L215 HydrophobicContact CD1-CB 4.02Å; L41-L215 HydrophobicContact CD1-CD2 4Å; L41-L215 HydrophobicContact CD1-CG 3.91Å; L41-L215 HydrophobicContact CD2-CD2 4.1Å; L41-A216 HydrophobicContact CD1-CB 3.93Å; L41-F219 HydrophobicContact CD1-CD2 4.14Å; L41-F219 HydrophobicContact CD1-CE2 4.18Å
42I92.3Very high91.1Very high1 Ų123.1 Ų23.11%0.00513%0.125CC..THydrogen-bonded Turntrans-78.9-24.1-177.9-167.3167.4000113.6F39 A40 P44 L45 F46 I49 W134 F143F39-I42 WeakPolarHBondContact O-CG2 3.35Å; A40-I42 PolarHBondContact O-N 3Å; I42-P44 VanDerWaalsContact C-CD 3.48Å; I42-L45 WeakPolarHBondContact O-CA 3.28Å; I42-L45 WeakPolarHBondContact O-CB 3.45Å; I42-L45 PolarHBondContact O-N 2.99Å; I42-F46 HydrophobicContact CB-CE2 4.47Å; I42-F46 HydrophobicContact CD1-CD1 4.48Å; I42-F46 HydrophobicContact CD1-CE1 3.95Å; I42-F46 HydrophobicContact CD1-CE2 4.47Å; I42-F46 HydrophobicContact CD1-CZ 3.93Å; I42-F46 HydrophobicContact CG1-CD2 4.37Å; I42-F46 HydrophobicContact CG1-CE1 4.3Å; I42-F46 HydrophobicContact CG1-CE2 4.14Å; I42-F46 HydrophobicContact CG1-CZ 4.1Å; I42-F46 HydrophobicContact CG2-CD2 4.46Å; I42-F46 HydrophobicContact CG2-CE2 3.69Å; I42-F46 HydrophobicContact CG2-CZ 3.96Å; I42-F46 PolarHBondContact O-N 3.42Å; I42-F46 VanDerWaalsContact O-N 3.17Å; I42-I49 HydrophobicContact CD1-CD1 3.94Å; I42-I49 HydrophobicContact CG1-CD1 3.87Å; I42-W134 HydrophobicContact CB-CH2 3.5Å; I42-W134 HydrophobicContact CB-CZ2 3.85Å; I42-W134 HydrophobicContact CB-CZ3 4.04Å; I42-W134 HydrophobicContact CD1-CD2 4.13Å; I42-W134 HydrophobicContact CD1-CH2 4.01Å; I42-W134 HydrophobicContact CD1-CZ2 3.52Å; I42-W134 HydrophobicContact CD1-CZ3 4.47Å; I42-W134 HydrophobicContact CG1-CH2 3.77Å; I42-W134 HydrophobicContact CG1-CZ2 3.53Å; I42-F143 HydrophobicContact CD1-CE2 3.58Å; I42-F143 HydrophobicContact CD1-CZ 3.75Å
43L89Confident90.5Very high55 Ų5523 Ų2329%0.28812%0.124SC..G310 helixtrans-52.7-49-168.4-63.6177.4000114.5F39 A40 L45 F46 F188 P192F39-L43 HydrophobicContact CE1-CD2 4.44Å; A40-L43 HydrophobicContact CB-CD1 3.94Å; A40-L43 PolarHBondContact O-N 2.8Å; L43-L45 PolarHBondContact O-N 3.28Å; L43-F46 HydrophobicContact CD2-CD2 4.37Å; L43-F46 HydrophobicContact CD2-CE2 4.04Å; L43-F188 HydrophobicContact CD1-CD1 3.55Å; L43-F188 HydrophobicContact CD1-CE1 3.62Å; L43-P192 HydrophobicContact CB-CG 4.37Å; L43-P192 HydrophobicContact CD1-CG 4.23Å
44P87.5Confident89.8Confident49 Ų4923.9 Ų23.932%0.31813%0.133SC..G310 helixtrans-74.9-16.2179.633.2-37.2000112.7I42 P192 A196I42-P44 VanDerWaalsContact C-CD 3.48Å; P44-P192 HydrophobicContact CG-CB 4.08Å; P44-P192 WeakPolarHBondContact CG-O 3.39Å; P44-A196 HydrophobicContact CB-CB 4.22Å; P44-A196 HydrophobicContact CG-CB 4.06Å
45L88.4Confident89.2Confident5 Ų530 Ų303%0.02616%0.158CC..G310 helixtrans-85.1-19.6-178-55.6175.6000112.1L41 I42 L43 S48 I49 W134 A199 F208 F209L41-L45 WeakPolarHBondContact O-CD1 3.29Å; I42-L45 WeakPolarHBondContact O-CA 3.28Å; I42-L45 WeakPolarHBondContact O-CB 3.45Å; I42-L45 PolarHBondContact O-N 2.99Å; L43-L45 PolarHBondContact O-N 3.28Å; L45-S48 CarbonylContact O-C 3.58Å; L45-S48 PolarHBondContact O-N 2.92Å; L45-S48 VanDerWaalsContact O-N 3.07Å; L45-I49 HydrophobicContact CB-CD1 3.77Å; L45-I49 HydrophobicContact CB-CG1 4.17Å; L45-I49 WeakPolarHBondContact O-CB 3.31Å; L45-I49 VanDerWaalsContact O-CG1 3.26Å; L45-I49 WeakPolarHBondContact O-CG1 3.3Å; L45-I49 PolarHBondContact O-N 3.31Å; L45-W134 HydrophobicContact CD1-CH2 4.47Å; L45-W134 HydrophobicContact CD1-CZ2 4.38Å; L45-A199 HydrophobicContact CD2-CB 3.21Å; L45-F208 HydrophobicContact CB-CE2 4.33Å; L45-F208 HydrophobicContact CD2-CD2 4.31Å; L45-F208 HydrophobicContact CD2-CE2 4.13Å; L45-F209 HydrophobicContact CD1-CB 4.24Å
46F85.9Confident88.2Confident29 Ų2933.3 Ų33.313%0.12718%0.178CC..Hα-helixtrans-50.3-51.2-176.9-88.2-62.6000113.6I42 L43 S48 I49 L50 V92 F143I42-F46 HydrophobicContact CB-CE2 4.47Å; I42-F46 HydrophobicContact CD1-CD1 4.48Å; I42-F46 HydrophobicContact CD1-CE1 3.95Å; I42-F46 HydrophobicContact CD1-CE2 4.47Å; I42-F46 HydrophobicContact CD1-CZ 3.93Å; I42-F46 HydrophobicContact CG1-CD2 4.37Å; I42-F46 HydrophobicContact CG1-CE1 4.3Å; I42-F46 HydrophobicContact CG1-CE2 4.14Å; I42-F46 HydrophobicContact CG1-CZ 4.1Å; I42-F46 HydrophobicContact CG2-CD2 4.46Å; I42-F46 HydrophobicContact CG2-CE2 3.69Å; I42-F46 HydrophobicContact CG2-CZ 3.96Å; I42-F46 PolarHBondContact O-N 3.42Å; I42-F46 VanDerWaalsContact O-N 3.17Å; L43-F46 HydrophobicContact CD2-CD2 4.37Å; L43-F46 HydrophobicContact CD2-CE2 4.04Å; F46-S48 VanDerWaalsContact C-N 3.33Å; F46-S48 PolarHBondContact O-N 3.39Å; F46-I49 PolarHBondContact O-N 3.47Å; F46-L50 VanDerWaalsContact O-CG 3.27Å; F46-L50 WeakPolarHBondContact O-CG 3.4Å; F46-L50 PolarHBondContact O-N 3.41Å; F46-V92 HydrophobicContact CE1-CG1 3.85Å; F46-V92 HydrophobicContact CZ-CG1 4.29Å; F46-F143 HydrophobicContact CD1-CZ 4.13Å; F46-F143 HydrophobicContact CE1-CE1 4.27Å; F46-F143 AromaticContact CE1-CZ 3.73Å; F46-F143 HydrophobicContact CE1-CZ 3.73Å
47P82.1Confident87.1Confident47 Ų4741.1 Ų41.131%0.30522%0.215SC..Hα-helixtrans-55.4-47.3176.8-27.737.2000112.8I49 L50 D51P47-I49 VanDerWaalsContact C-N 3.34Å; P47-I49 PolarHBondContact O-N 2.91Å; P47-L50 PolarHBondContact O-N 3.26Å; P47-D51 PolarHBondContact O-N 2.92Å
48S84.6Confident86.4Confident57 Ų5741.4 Ų41.440%0.39922%0.216SC..Hα-helixtrans-67.9-32.7-180-55.60000112.9L45 F46 Y52 F208L45-S48 CarbonylContact O-C 3.58Å; L45-S48 PolarHBondContact O-N 2.92Å; L45-S48 VanDerWaalsContact O-N 3.07Å; F46-S48 VanDerWaalsContact C-N 3.33Å; F46-S48 PolarHBondContact O-N 3.39Å; S48-Y52 WeakPolarHBondContact O-CB 3.28Å; S48-Y52 PolarHBondContact O-N 3.2Å; S48-F208 VanDerWaalsContact C-CZ 3.47Å
49I87.9Confident85.8Confident0 Ų043.5 Ų43.50%024%0.238CC..Hα-helixtrans-69.4-43.2177.5-70.9170.9000109.6I42 L45 F46 P47 Y52 Y53 W134 F143 F208 F209I42-I49 HydrophobicContact CD1-CD1 3.94Å; I42-I49 HydrophobicContact CG1-CD1 3.87Å; L45-I49 HydrophobicContact CB-CD1 3.77Å; L45-I49 HydrophobicContact CB-CG1 4.17Å; L45-I49 WeakPolarHBondContact O-CB 3.31Å; L45-I49 VanDerWaalsContact O-CG1 3.26Å; L45-I49 WeakPolarHBondContact O-CG1 3.3Å; L45-I49 PolarHBondContact O-N 3.31Å; F46-I49 PolarHBondContact O-N 3.47Å; P47-I49 VanDerWaalsContact C-N 3.34Å; P47-I49 PolarHBondContact O-N 2.91Å; I49-Y52 WeakPolarHBondContact O-CB 3.11Å; I49-Y52 PolarHBondContact O-N 3.49Å; I49-Y53 HydrophobicContact CG2-CD2 3.69Å; I49-Y53 HydrophobicContact CG2-CE2 3.53Å; I49-Y53 WeakPolarHBondContact O-CD2 3.19Å; I49-Y53 PolarHBondContact O-N 3.07Å; I49-W134 HydrophobicContact CD1-CZ2 4.18Å; I49-F143 HydrophobicContact CD1-CE2 4.13Å; I49-F143 HydrophobicContact CD1-CZ 4.34Å; I49-F143 HydrophobicContact CG2-CD1 4.36Å; I49-F143 HydrophobicContact CG2-CD2 4.26Å; I49-F143 HydrophobicContact CG2-CE1 4.03Å; I49-F143 HydrophobicContact CG2-CE2 3.94Å; I49-F143 HydrophobicContact CG2-CG 4.45Å; I49-F143 HydrophobicContact CG2-CZ 3.8Å; I49-F208 HydrophobicContact CB-CZ 4.32Å; I49-F208 HydrophobicContact CG1-CE2 4.03Å; I49-F208 HydrophobicContact CG1-CZ 3.59Å; I49-F209 HydrophobicContact CD1-CB 4.1Å; I49-F209 HydrophobicContact CD1-CD1 4.31Å; I49-F209 HydrophobicContact CD1-CG 4.28Å; I49-F209 HydrophobicContact CG1-CB 4.22Å; I49-F209 HydrophobicContact CG1-CD1 3.79Å; I49-F209 HydrophobicContact CG1-CE1 4.46Å; I49-F209 HydrophobicContact CG1-CG 4.22Å
50L83.9Confident85.3Confident4 Ų446.9 Ų46.92%0.02125%0.253CS..Hα-helixtrans-63.8-43175.8-65.2171.8000111F46 P47 Y52 Y53 S54 Y61 F88 F140F46-L50 VanDerWaalsContact O-CG 3.27Å; F46-L50 WeakPolarHBondContact O-CG 3.4Å; F46-L50 PolarHBondContact O-N 3.41Å; P47-L50 PolarHBondContact O-N 3.26Å; L50-Y52 VanDerWaalsContact C-N 3.28Å; L50-Y52 PolarHBondContact O-N 3.14Å; L50-Y53 PolarHBondContact O-N 3.4Å; L50-S54 WeakPolarHBondContact O-CB 3.23Å; L50-S54 PolarHBondContact O-N 2.91Å; L50-Y61 HydrophobicContact CB-CE2 4.36Å; L50-Y61 HydrophobicContact CD2-CE2 4.15Å; L50-F88 HydrophobicContact CD1-CB 3.78Å; L50-F88 HydrophobicContact CD1-CD1 3.46Å; L50-F88 VanDerWaalsContact CD1-CD1 3.46Å; L50-F88 HydrophobicContact CD1-CD2 4.46Å; L50-F88 HydrophobicContact CD1-CE1 4.2Å; L50-F88 HydrophobicContact CD1-CG 3.65Å; L50-F88 HydrophobicContact CD2-CD1 3.7Å; L50-F88 HydrophobicContact CD2-CE1 3.52Å; L50-F88 HydrophobicContact CD2-CG 4.36Å; L50-F88 HydrophobicContact CD2-CZ 4.01Å; L50-F88 HydrophobicContact CG-CD1 4.22Å; L50-F140 HydrophobicContact CD2-CE2 3.9Å
51D81.7Confident84.9Confident38 Ų3847.5 Ų47.520%0.20326%0.255CS..Hα-helixtrans-63.8-30.8174.1-79.9-14.3000113.5P47 S54 R81P47-D51 PolarHBondContact O-N 2.92Å; D51-S54 PolarHBondContact O-OG 2.95Å; D51-R81 VanDerWaalsContact CG-NH2 3.29Å; D51-R81 IonicContact OD1-NE 3.12Å; D51-R81 IonicContact OD1-NH2 3.37Å; D51-R81 IonicContact OD2-CZ 3.28Å; D51-R81 IonicContact OD2-NE 2.85Å; D51-R81 IonicContact OD2-NH2 2.92Å; D51-R81 PolarHBondContact OD2-NH2 3Å
52Y85.6Confident84.5Confident75 Ų7550.8 Ų50.829%0.29427%0.272SS..Hα-helixtrans-69-46.6175169.9-92.6000110.8S48 I49 L50 K55 F208 F209S48-Y52 WeakPolarHBondContact O-CB 3.28Å; S48-Y52 PolarHBondContact O-N 3.2Å; I49-Y52 WeakPolarHBondContact O-CB 3.11Å; I49-Y52 PolarHBondContact O-N 3.49Å; L50-Y52 VanDerWaalsContact C-N 3.28Å; L50-Y52 PolarHBondContact O-N 3.14Å; Y52-K55 PolarHBondContact O-N 3.26Å; Y52-F208 HydrophobicContact CD2-CE1 4.42Å; Y52-F208 HydrophobicContact CG-CE1 4.25Å; Y52-F209 HydrophobicContact CD1-CE1 4.25Å; Y52-F209 HydrophobicContact CE1-CE1 4.38Å
53Y86.1Confident84.3Confident0 Ų053.8 Ų53.80%029%0.293CS..Hα-helixtrans-74.3-25.3179.5-71.9-59.6000113.6I49 L50 K55 T56 S137 F140 F143I49-Y53 HydrophobicContact CG2-CD2 3.69Å; I49-Y53 HydrophobicContact CG2-CE2 3.53Å; I49-Y53 WeakPolarHBondContact O-CD2 3.19Å; I49-Y53 PolarHBondContact O-N 3.07Å; L50-Y53 PolarHBondContact O-N 3.4Å; Y53-K55 PolarHBondContact O-N 2.67Å; Y53-T56 PolarHBondContact O-N 3.13Å; Y53-T56 PolarHBondContact O-OG1 3.45Å; Y53-S137 PolarHBondContact OH-OG 3.18Å; Y53-F140 HydrophobicContact CD1-CB 3.94Å; Y53-F140 HydrophobicContact CD2-CB 4.27Å; Y53-F140 AromaticContact CD2-CD2 3.74Å; Y53-F140 HydrophobicContact CD2-CD2 3.74Å; Y53-F140 HydrophobicContact CD2-CG 4.49Å; Y53-F140 HydrophobicContact CE1-CB 4.49Å; Y53-F140 HydrophobicContact CE2-CD2 4.39Å; Y53-F140 HydrophobicContact CG-CB 3.84Å; Y53-F140 HydrophobicContact CG-CD2 4.01Å; Y53-F140 HydrophobicContact CG-CG 4.38Å; Y53-F143 HydrophobicContact CE2-CB 3.84Å; Y53-F143 HydrophobicContact CE2-CD1 4.32Å; Y53-F143 HydrophobicContact CE2-CD2 4.42Å; Y53-F143 AromaticContact CE2-CG 3.93Å; Y53-F143 HydrophobicContact CE2-CG 3.93Å
54S83.1Confident84.1Confident47 Ų4753.7 Ų53.733%0.32929%0.293SS..Hα-helixtrans-60.5-29.2175.777.60000112.9L50 D51 T56 Y61L50-S54 WeakPolarHBondContact O-CB 3.23Å; L50-S54 PolarHBondContact O-N 2.91Å; D51-S54 PolarHBondContact O-OG 2.95Å; S54-T56 VanDerWaalsContact C-N 3.31Å; S54-T56 PolarHBondContact O-N 3.5Å; S54-Y61 VanDerWaalsContact CB-CE1 3.45Å; S54-Y61 VanDerWaalsContact CB-OH 3.3Å; S54-Y61 WeakPolarHBondContact CB-OH 3.44Å
55K84Confident84.2Confident167 Ų16752.6 Ų52.673%0.72628%0.283SS*.THydrogen-bonded Turntrans-77.7-14.4177.9-62175.5-174.9179.20114Y52 Y53 E57Y52-K55 PolarHBondContact O-N 3.26Å; Y53-K55 PolarHBondContact O-N 2.67Å; K55-E57 VanDerWaalsContact C-N 3.35Å
56T76.1Confident84.2Confident70 Ų7060 Ų6043%0.42931%0.311SS..THydrogen-bonded Turntrans-90.43.9-175.555.30000113.9Y53 S54 D58Y53-T56 PolarHBondContact O-N 3.13Å; Y53-T56 PolarHBondContact O-OG1 3.45Å; S54-T56 VanDerWaalsContact C-N 3.31Å; S54-T56 PolarHBondContact O-N 3.5Å; T56-D58 PolarHBondContact O-N 2.94Å
57E73.9Confident84.4Confident166 Ų16660.4 Ų60.478%0.77632%0.323SS*.THydrogen-bonded Turntrans49.928.8-177-62.5-170.3171.200114.2K55 G59K55-E57 VanDerWaalsContact C-N 3.35Å; E57-G59 PolarHBondContact O-N 3.1Å
58D82.1Confident84.7Confident31 Ų3158.3 Ų58.317%0.16631%0.309CS..  trans-63.6117.7-179.1-176.6-50.9000110.3T56 F60 Y61 L62 F140T56-D58 PolarHBondContact O-N 2.94Å; D58-F60 PolarHBondContact O-N 2.86Å; D58-F60 WeakPolarHBondContact OD1-CA 3.41Å; D58-F60 VanDerWaalsContact OD1-CB 3.3Å; D58-F60 WeakPolarHBondContact OD1-CB 3.09Å; D58-F60 PolarHBondContact OD1-N 3.31Å; D58-Y61 WeakPolarHBondContact O-CB 3.47Å; D58-Y61 PolarHBondContact O-N 3.19Å; D58-Y61 VanDerWaalsContact O-N 3.14Å; D58-Y61 PolarHBondContact OD1-N 3.45Å; D58-Y61 VanDerWaalsContact OD1-N 3.16Å; D58-L62 WeakPolarHBondContact O-CG 3.3Å; D58-L62 PolarHBondContact O-N 2.89Å; D58-F140 HydrophobicContact CB-CB 4.38Å; D58-F140 WeakPolarHBondContact OD2-CB 3.39Å; D58-F140 PolarHBondContact OD2-N 3.09Å
59G82.8Confident85Confident45 Ų4558.6 Ų58.646%0.46431%0.307SS..Hα-helixtrans-61.2-27.6-17600000114.1E57 S63E57-G59 PolarHBondContact O-N 3.1Å; G59-S63 PolarHBondContact O-N 3.33Å; G59-S63 VanDerWaalsContact O-N 3.16Å; G59-S63 PolarHBondContact O-OG 3.3Å
60F83.6Confident85.2Confident98 Ų9866.7 Ų66.743%0.4334%0.337SS..Hα-helixtrans-78-39.2177.5-172.2-107.5000111.2D58 S63 L64 F140 L144D58-F60 PolarHBondContact O-N 2.86Å; D58-F60 WeakPolarHBondContact OD1-CA 3.41Å; D58-F60 VanDerWaalsContact OD1-CB 3.3Å; D58-F60 WeakPolarHBondContact OD1-CB 3.09Å; D58-F60 PolarHBondContact OD1-N 3.31Å; F60-S63 PolarHBondContact O-N 3.45Å; F60-L64 HydrophobicContact CE1-CD1 4.45Å; F60-L64 PolarHBondContact O-N 3.37Å; F60-F140 AromaticContact CD1-CD1 3.73Å; F60-F140 HydrophobicContact CD1-CD1 3.73Å; F60-F140 AromaticContact CD1-CE1 3.84Å; F60-F140 HydrophobicContact CD1-CE1 3.84Å; F60-F140 HydrophobicContact CE1-CD1 4.38Å; F60-F140 HydrophobicContact CE1-CE1 4.12Å; F60-L144 HydrophobicContact CE1-CB 4.28Å; F60-L144 HydrophobicContact CE1-CD2 3.31Å; F60-L144 HydrophobicContact CE1-CG 4.38Å; F60-L144 HydrophobicContact CZ-CD2 3.57Å
61Y87.3Confident85.6Confident14 Ų1468.1 Ų68.16%0.05534%0.343CS..Hα-helixtrans-58.4-49.8169.2172.2-94.7000111.3L50 S54 D58 S63 L64 Q65 F88 F140L50-Y61 HydrophobicContact CB-CE2 4.36Å; L50-Y61 HydrophobicContact CD2-CE2 4.15Å; S54-Y61 VanDerWaalsContact CB-CE1 3.45Å; S54-Y61 VanDerWaalsContact CB-OH 3.3Å; S54-Y61 WeakPolarHBondContact CB-OH 3.44Å; D58-Y61 WeakPolarHBondContact O-CB 3.47Å; D58-Y61 PolarHBondContact O-N 3.19Å; D58-Y61 VanDerWaalsContact O-N 3.14Å; D58-Y61 PolarHBondContact OD1-N 3.45Å; D58-Y61 VanDerWaalsContact OD1-N 3.16Å; Y61-S63 PolarHBondContact O-N 3.33Å; Y61-L64 PolarHBondContact O-N 3.16Å; Y61-L64 VanDerWaalsContact O-N 3.12Å; Y61-Q65 HydrophobicContact CE1-CB 4.26Å; Y61-Q65 WeakPolarHBondContact O-CB 3.46Å; Y61-Q65 PolarHBondContact O-N 3.49Å; Y61-Q65 PolarHBondContact OH-OE1 2.76Å; Y61-F88 HydrophobicContact CD2-CE2 4.41Å; Y61-F88 HydrophobicContact CD2-CZ 4.18Å; Y61-F88 AromaticContact CE2-CE2 3.8Å; Y61-F88 HydrophobicContact CE2-CE2 3.8Å; Y61-F88 AromaticContact CE2-CZ 3.94Å; Y61-F88 HydrophobicContact CE2-CZ 3.94Å; Y61-F140 HydrophobicContact CD2-CD1 4.41Å; Y61-F140 HydrophobicContact CD2-CD2 4.13Å; Y61-F140 HydrophobicContact CD2-CE1 4.43Å; Y61-F140 HydrophobicContact CD2-CE2 4.13Å; Y61-F140 HydrophobicContact CD2-CG 4.28Å; Y61-F140 HydrophobicContact CD2-CZ 4.29Å
62L86.5Confident86.1Confident69 Ų6966.7 Ų66.736%0.36134%0.337SS..Hα-helixtrans-59.6-32.7-179.8-69.9172.6000112.7D58 R66D58-L62 WeakPolarHBondContact O-CG 3.3Å; D58-L62 PolarHBondContact O-N 2.89Å; L62-R66 WeakPolarHBondContact O-CG 3.46Å; L62-R66 PolarHBondContact O-N 3.31Å; L62-R66 PolarHBondContact O-NE 3.42Å
63S87.4Confident86.4Confident63 Ų6368.8 Ų68.844%0.44136%0.357SS..Hα-helixtrans-68.7-42177.3-61.40000112G59 F60 Y61 G67G59-S63 PolarHBondContact O-N 3.33Å; G59-S63 VanDerWaalsContact O-N 3.16Å; G59-S63 PolarHBondContact O-OG 3.3Å; F60-S63 PolarHBondContact O-N 3.45Å; Y61-S63 PolarHBondContact O-N 3.33Å; S63-G67 PolarHBondContact O-N 3.42Å
64L86.8Confident86.7Confident54 Ų5473.3 Ų73.328%0.28338%0.379SS..Hα-helixtrans-69.5-40.4174-69.5-177.9000111.8F60 Y61 R66 G67 V68 F88 F140F60-L64 HydrophobicContact CE1-CD1 4.45Å; F60-L64 PolarHBondContact O-N 3.37Å; Y61-L64 PolarHBondContact O-N 3.16Å; Y61-L64 VanDerWaalsContact O-N 3.12Å; L64-R66 VanDerWaalsContact C-N 3.31Å; L64-R66 PolarHBondContact O-N 3.46Å; L64-G67 WeakPolarHBondContact O-CA 3.34Å; L64-G67 PolarHBondContact O-N 3.42Å; L64-V68 PolarHBondContact O-N 3.15Å; L64-F88 HydrophobicContact CB-CZ 3.83Å; L64-F140 HydrophobicContact CD1-CE1 3.66Å; L64-F140 HydrophobicContact CD1-CZ 3.85Å
65Q88.1Confident87.1Confident25 Ų2571.1 Ų71.112%0.11736%0.364CS..Hα-helixtrans-57.4-43.9176.7-174.964.247.100111.2Y61 G67 V68 D69 N84 F88Y61-Q65 HydrophobicContact CE1-CB 4.26Å; Y61-Q65 WeakPolarHBondContact O-CB 3.46Å; Y61-Q65 PolarHBondContact O-N 3.49Å; Y61-Q65 PolarHBondContact OH-OE1 2.76Å; Q65-G67 VanDerWaalsContact C-N 3.26Å; Q65-G67 PolarHBondContact O-N 3.06Å; Q65-V68 WeakPolarHBondContact O-CB 3.31Å; Q65-V68 PolarHBondContact O-N 2.82Å; Q65-D69 PolarHBondContact NE2-OD1 3.47Å; Q65-D69 VanDerWaalsContact O-CG 3.23Å; Q65-D69 PolarHBondContact O-N 3.23Å; Q65-N84 PolarHBondContact NE2-ND2 3.42Å; Q65-N84 PolarHBondContact NE2-OD1 3.07Å; Q65-F88 HydrophobicContact CB-CE2 4.08Å
66R89.7Confident87.4Confident162 Ų16265.8 Ų65.861%0.61136%0.356SS*.Hα-helixtrans-57.7-37.3174.6-77.8-179.8-118159.1-4.4113.1L62 L64 W70L62-R66 WeakPolarHBondContact O-CG 3.46Å; L62-R66 PolarHBondContact O-N 3.31Å; L62-R66 PolarHBondContact O-NE 3.42Å; L64-R66 VanDerWaalsContact C-N 3.31Å; L64-R66 PolarHBondContact O-N 3.46Å; R66-W70 VanDerWaalsContact O-CB 3.29Å; R66-W70 WeakPolarHBondContact O-CB 3.24Å; R66-W70 PolarHBondContact O-N 2.63Å
67G89.1Confident88.1Confident36 Ų3663.1 Ų63.137%0.37134%0.339SS..Hα-helixtrans-66.7-40.617500000112.6S63 L64 Q65 F71S63-G67 PolarHBondContact O-N 3.42Å; L64-G67 WeakPolarHBondContact O-CA 3.34Å; L64-G67 PolarHBondContact O-N 3.42Å; Q65-G67 VanDerWaalsContact C-N 3.26Å; Q65-G67 PolarHBondContact O-N 3.06Å; G67-F71 PolarHBondContact O-N 2.86Å
68V89.7Confident88.9Confident4 Ų458 Ų582%0.02432%0.32CS..Hα-helixtrans-64.1-46174.7174.30000110.8L64 Q65 F71 A72 L87 F88 L91L64-V68 PolarHBondContact O-N 3.15Å; Q65-V68 WeakPolarHBondContact O-CB 3.31Å; Q65-V68 PolarHBondContact O-N 2.82Å; V68-F71 PolarHBondContact O-N 3.08Å; V68-A72 WeakPolarHBondContact O-CB 3.27Å; V68-A72 PolarHBondContact O-N 2.98Å; V68-L87 HydrophobicContact CG1-CB 4.27Å; V68-L87 HydrophobicContact CG1-CD2 3.75Å; V68-L87 HydrophobicContact CG1-CG 3.95Å; V68-F88 HydrophobicContact CB-CD2 4.28Å; V68-F88 HydrophobicContact CG1-CB 4.3Å; V68-F88 HydrophobicContact CG1-CD2 4.4Å; V68-F88 HydrophobicContact CG2-CB 4.22Å; V68-F88 HydrophobicContact CG2-CD2 3.75Å; V68-F88 HydrophobicContact CG2-CE2 4.21Å; V68-F88 HydrophobicContact CG2-CG 3.92Å; V68-L91 HydrophobicContact CG2-CD2 3.57Å
69D90.4Very high89.1Confident63 Ų6363.2 Ų63.234%0.33736%0.356SS..Hα-helixtrans-65.4-41.8179.8-64.1-22.2000111.3Q65 F71 A72 V73 N84Q65-D69 PolarHBondContact NE2-OD1 3.47Å; Q65-D69 VanDerWaalsContact O-CG 3.23Å; Q65-D69 PolarHBondContact O-N 3.23Å; D69-F71 VanDerWaalsContact C-N 3.34Å; D69-F71 PolarHBondContact O-N 2.91Å; D69-A72 PolarHBondContact O-N 2.97Å; D69-V73 WeakPolarHBondContact O-CG2 3.19Å; D69-V73 PolarHBondContact O-N 3.43Å; D69-N84 PolarHBondContact OD1-ND2 3.08Å
70W92.6Very high89.2Confident170 Ų17064.7 Ų64.764%0.64435%0.351SS*.Hα-helixtrans-58.5-46.2173.7172.181.6000111.8R66 V73 M74R66-W70 VanDerWaalsContact O-CB 3.29Å; R66-W70 WeakPolarHBondContact O-CB 3.24Å; R66-W70 PolarHBondContact O-N 2.63Å; W70-V73 PolarHBondContact O-N 3.36Å; W70-M74 HydrophobicContact CE3-CE 4.06Å; W70-M74 HydrophobicContact CH2-CE 3.07Å; W70-M74 HydrophobicContact CZ2-CE 3.58Å; W70-M74 HydrophobicContact CZ3-CE 3.33Å; W70-M74 WeakPolarHBondContact O-CB 3.48Å; W70-M74 PolarHBondContact O-N 3.39Å
71F91.4Very high89.1Confident33 Ų3368.2 Ų68.215%0.14536%0.361CS..Hα-helixtrans-65.6-42.3177.6-177.5-95.1000111.7G67 V68 D69 V73 M74 V75 L87 I422 T426G67-F71 PolarHBondContact O-N 2.86Å; V68-F71 PolarHBondContact O-N 3.08Å; D69-F71 VanDerWaalsContact C-N 3.34Å; D69-F71 PolarHBondContact O-N 2.91Å; F71-V73 VanDerWaalsContact C-N 3.35Å; F71-V73 PolarHBondContact O-N 3.32Å; F71-M74 HydrophobicContact CD2-CE 4.03Å; F71-M74 WeakPolarHBondContact O-CB 3.17Å; F71-M74 PolarHBondContact O-N 2.63Å; F71-V75 HydrophobicContact CD1-CG1 4.32Å; F71-V75 HydrophobicContact CD1-CG2 4.47Å; F71-V75 HydrophobicContact CD2-CG1 4.41Å; F71-V75 HydrophobicContact CE1-CG1 3.9Å; F71-V75 HydrophobicContact CE1-CG2 4.31Å; F71-V75 HydrophobicContact CE2-CG1 3.99Å; F71-V75 HydrophobicContact CZ-CG1 3.73Å; F71-V75 WeakPolarHBondContact O-CG2 3.28Å; F71-V75 PolarHBondContact O-N 3.39Å; F71-L87 HydrophobicContact CD1-CD1 3.8Å; F71-L87 HydrophobicContact CD1-CD2 3.95Å; F71-L87 HydrophobicContact CD1-CG 4.38Å; F71-L87 HydrophobicContact CE1-CD1 3.8Å; F71-I422 HydrophobicContact CE2-CG2 4.04Å; F71-I422 HydrophobicContact CZ-CG2 4.05Å; F71-T426 WeakPolarHBondContact CZ-OG1 3.42Å
72A91.7Very high88.8Confident8 Ų869.4 Ų69.47%0.06637%0.367CS..Hα-helixtrans-57.1-46.7176.400000112V68 D69 V75 G76 M77 L87V68-A72 WeakPolarHBondContact O-CB 3.27Å; V68-A72 PolarHBondContact O-N 2.98Å; D69-A72 PolarHBondContact O-N 2.97Å; A72-V75 PolarHBondContact O-N 3.47Å; A72-G76 PolarHBondContact O-N 2.89Å; A72-M77 HydrophobicContact CB-CB 4.2Å; A72-M77 HydrophobicContact CB-CE 3.64Å; A72-M77 HydrophobicContact CB-SD 4.4Å; A72-M77 WeakPolarHBondContact O-CB 3.38Å; A72-M77 PolarHBondContact O-N 2.94Å; A72-L87 HydrophobicContact CB-CD2 3.86Å
73V92.8Very high88.7Confident119 Ų11966.8 Ų66.872%0.72135%0.352SS*.Hα-helixtrans-64.5-43.8176.5172.70000110.9D69 W70 F71 V75 G76D69-V73 WeakPolarHBondContact O-CG2 3.19Å; D69-V73 PolarHBondContact O-N 3.43Å; W70-V73 PolarHBondContact O-N 3.36Å; F71-V73 VanDerWaalsContact C-N 3.35Å; F71-V73 PolarHBondContact O-N 3.32Å; V73-V75 VanDerWaalsContact C-N 3.31Å; V73-V75 PolarHBondContact O-N 3.45Å; V73-G76 PolarHBondContact O-N 3.1Å; V73-G76 VanDerWaalsContact O-N 3.14Å
74M92.8Very high88.6Confident95 Ų9565.5 Ų65.547%0.46834%0.34SS..Hα-helixtrans-58.6-41.2179.4-177.3-132.3-68.800112.5W70 F71 G76W70-M74 HydrophobicContact CE3-CE 4.06Å; W70-M74 HydrophobicContact CH2-CE 3.07Å; W70-M74 HydrophobicContact CZ2-CE 3.58Å; W70-M74 HydrophobicContact CZ3-CE 3.33Å; W70-M74 WeakPolarHBondContact O-CB 3.48Å; W70-M74 PolarHBondContact O-N 3.39Å; F71-M74 HydrophobicContact CD2-CE 4.03Å; F71-M74 WeakPolarHBondContact O-CB 3.17Å; F71-M74 PolarHBondContact O-N 2.63Å; M74-G76 VanDerWaalsContact C-N 3.32Å
75V90.9Very high88.4Confident1 Ų163.7 Ų63.71%0.00633%0.332CS..THydrogen-bonded Turntrans-881.3-179.2-54.10000113.5F71 A72 V73 M77 T426 W429F71-V75 HydrophobicContact CD1-CG1 4.32Å; F71-V75 HydrophobicContact CD1-CG2 4.47Å; F71-V75 HydrophobicContact CD2-CG1 4.41Å; F71-V75 HydrophobicContact CE1-CG1 3.9Å; F71-V75 HydrophobicContact CE1-CG2 4.31Å; F71-V75 HydrophobicContact CE2-CG1 3.99Å; F71-V75 HydrophobicContact CZ-CG1 3.73Å; F71-V75 WeakPolarHBondContact O-CG2 3.28Å; F71-V75 PolarHBondContact O-N 3.39Å; A72-V75 PolarHBondContact O-N 3.47Å; V73-V75 VanDerWaalsContact C-N 3.31Å; V73-V75 PolarHBondContact O-N 3.45Å; V75-M77 VanDerWaalsContact C-N 3.34Å; V75-M77 HydrophobicContact CG2-CB 4.01Å; V75-T426 HydrophobicContact CG1-CG2 4.19Å; V75-W429 HydrophobicContact CB-CB 4.02Å; V75-W429 HydrophobicContact CG2-CB 3.82Å; V75-W429 HydrophobicContact CG2-CG 4.07Å; V75-W429 CarbonylContact O-C 3.55Å; V75-W429 VanDerWaalsContact O-CB 3.28Å; V75-W429 WeakPolarHBondContact O-CB 3.49Å
76G89.9Confident88.2Confident55 Ų5563.9 Ų63.957%0.56734%0.335SS*.THydrogen-bonded Turntrans70.925.6-179.200000114.2A72 V73 M74A72-G76 PolarHBondContact O-N 2.89Å; V73-G76 PolarHBondContact O-N 3.1Å; V73-G76 VanDerWaalsContact O-N 3.14Å; M74-G76 VanDerWaalsContact C-N 3.32Å
77M91.5Very high88.1Confident15 Ų1556.7 Ų56.77%0.07431%0.309CS..  trans-68.3130.1178.8-174-179.190.400110.5A72 V75 N84 L87 W429A72-M77 HydrophobicContact CB-CB 4.2Å; A72-M77 HydrophobicContact CB-CE 3.64Å; A72-M77 HydrophobicContact CB-SD 4.4Å; A72-M77 WeakPolarHBondContact O-CB 3.38Å; A72-M77 PolarHBondContact O-N 2.94Å; V75-M77 VanDerWaalsContact C-N 3.34Å; V75-M77 HydrophobicContact CG2-CB 4.01Å; M77-N84 HydrophobicContact CE-CB 4.39Å; M77-L87 HydrophobicContact CE-CD2 3.96Å; M77-L87 HydrophobicContact SD-CB 4.34Å; M77-L87 HydrophobicContact SD-CD2 3.92Å; M77-W429 HydrophobicContact CB-CD2 4.06Å; M77-W429 HydrophobicContact CB-CE3 4.43Å; M77-W429 HydrophobicContact CB-CG 4.23Å; M77-W429 HydrophobicContact CG-CD2 3.88Å; M77-W429 HydrophobicContact CG-CE3 4.22Å; M77-W429 HydrophobicContact CG-CG 4.44Å; M77-W429 HydrophobicContact CG-CH2 4.07Å; M77-W429 HydrophobicContact CG-CZ2 3.69Å; M77-W429 HydrophobicContact CG-CZ3 4.33Å; M77-W429 HydrophobicContact SD-CZ2 4.11Å
78P89.8Confident87.9Confident57 Ų5755.1 Ų55.137%0.3729%0.291SS..  trans-57.6144175.9-24.133.8000111.9E80 Y83 W429P78-E80 PolarHBondContact O-N 3.4Å; P78-Y83 HydrophobicContact CB-CD2 4.33Å; P78-Y83 HydrophobicContact CB-CE2 4.35Å; P78-Y83 HydrophobicContact CG-CE2 4.39Å; P78-W429 HydrophobicContact CG-CZ3 4.07Å
79P85.6Confident87.5Confident142 Ų14256 Ų5692%0.92230%0.302SS*.  trans-76.363.8-179.533.4-36.3000111
80E85.9Confident87.2Confident76 Ų7653.5 Ų53.536%0.35529%0.291SS..  trans-105.7134176.2-165.2179162.400110P78 K82 Y83 N84 H307P78-E80 PolarHBondContact O-N 3.4Å; E80-K82 VanDerWaalsContact C-N 3.27Å; E80-K82 PolarHBondContact O-N 3.3Å; E80-Y83 HydrophobicContact CB-CD2 3.47Å; E80-Y83 VanDerWaalsContact CB-CD2 3.47Å; E80-Y83 HydrophobicContact CB-CE2 3.82Å; E80-Y83 HydrophobicContact CB-CG 4.15Å; E80-Y83 HydrophobicContact CG-CD2 4.38Å; E80-Y83 HydrophobicContact CG-CE2 4.42Å; E80-Y83 PolarHBondContact O-N 3.12Å; E80-Y83 VanDerWaalsContact O-N 3.13Å; E80-Y83 WeakPolarHBondContact OE2-CE2 3.34Å; E80-Y83 VanDerWaalsContact OE2-CZ 3.22Å; E80-Y83 PolarHBondContact OE2-OH 3.44Å; E80-N84 PolarHBondContact O-N 3.15Å; E80-N84 VanDerWaalsContact O-N 3.08Å; E80-H307 IonicContact OE1-CD2 2.67Å; E80-H307 IonicContact OE1-NE2 2.69Å; E80-H307 PolarHBondContact OE1-NE2 3.46Å
81R81.4Confident86.8Confident171 Ų17148.4 Ų48.465%0.64528%0.276SS*.Hα-helixtrans-54.4-43.4-176.5-175.9175176.1177.8-3.6112.4D51 Y83 N84 S85D51-R81 VanDerWaalsContact CG-NH2 3.29Å; D51-R81 IonicContact OD1-NE 3.12Å; D51-R81 IonicContact OD1-NH2 3.37Å; D51-R81 IonicContact OD2-CZ 3.28Å; D51-R81 IonicContact OD2-NE 2.85Å; D51-R81 IonicContact OD2-NH2 2.92Å; D51-R81 PolarHBondContact OD2-NH2 3Å; R81-Y83 PolarHBondContact O-N 2.93Å; R81-N84 PolarHBondContact O-N 2.9Å; R81-S85 PolarHBondContact O-N 3.38Å; R81-S85 PolarHBondContact O-OG 3.16Å; R81-S85 VanDerWaalsContact O-OG 3.06Å
82K80.1Confident86.4Confident40 Ų4047.4 Ų47.417%0.17427%0.272CS..Hα-helixtrans-67-37.6-178-169172.3173.8-167.60112.3E80 S85 V86 H307 F312E80-K82 VanDerWaalsContact C-N 3.27Å; E80-K82 PolarHBondContact O-N 3.3Å; K82-S85 PolarHBondContact O-N 3.48Å; K82-V86 WeakPolarHBondContact O-CG2 3.44Å; K82-V86 PolarHBondContact O-N 3.41Å; K82-H307 PolarHBondContact NZ-ND1 2.94Å; K82-F312 PolarHBondContact NZ-O 3.48Å
83Y85.5Confident86.1Confident14 Ų1448.7 Ų48.76%0.05529%0.286CS..Hα-helixtrans-66.5-41.8175.3-60.3-34.3000111.6P78 E80 R81 V86 L87 F304 H307 W429P78-Y83 HydrophobicContact CB-CD2 4.33Å; P78-Y83 HydrophobicContact CB-CE2 4.35Å; P78-Y83 HydrophobicContact CG-CE2 4.39Å; E80-Y83 HydrophobicContact CB-CD2 3.47Å; E80-Y83 VanDerWaalsContact CB-CD2 3.47Å; E80-Y83 HydrophobicContact CB-CE2 3.82Å; E80-Y83 HydrophobicContact CB-CG 4.15Å; E80-Y83 HydrophobicContact CG-CD2 4.38Å; E80-Y83 HydrophobicContact CG-CE2 4.42Å; E80-Y83 PolarHBondContact O-N 3.12Å; E80-Y83 VanDerWaalsContact O-N 3.13Å; E80-Y83 WeakPolarHBondContact OE2-CE2 3.34Å; E80-Y83 VanDerWaalsContact OE2-CZ 3.22Å; E80-Y83 PolarHBondContact OE2-OH 3.44Å; R81-Y83 PolarHBondContact O-N 2.93Å; Y83-V86 PolarHBondContact O-N 3.45Å; Y83-L87 VanDerWaalsContact O-CB 3.27Å; Y83-L87 WeakPolarHBondContact O-CB 3.46Å; Y83-L87 PolarHBondContact O-N 2.74Å; Y83-F304 AromaticContact CD1-CD1 3.87Å; Y83-F304 HydrophobicContact CD1-CD1 3.87Å; Y83-F304 HydrophobicContact CD1-CE1 4.33Å; Y83-F304 HydrophobicContact CE1-CD1 4.47Å; Y83-H307 AromaticContact CE1-CD2 3.62Å; Y83-H307 AromaticContact CZ-CD2 3.99Å; Y83-W429 AromaticContact CD1-CH2 3.89Å; Y83-W429 HydrophobicContact CD1-CH2 3.89Å; Y83-W429 AromaticContact CD1-CZ2 3.96Å; Y83-W429 HydrophobicContact CD1-CZ2 3.96Å; Y83-W429 AromaticContact CD2-CH2 3.63Å; Y83-W429 HydrophobicContact CD2-CH2 3.63Å; Y83-W429 HydrophobicContact CD2-CZ2 4.18Å; Y83-W429 HydrophobicContact CD2-CZ3 4.5Å; Y83-W429 AromaticContact CE1-CH2 3.92Å; Y83-W429 HydrophobicContact CE1-CH2 3.92Å; Y83-W429 HydrophobicContact CE1-CZ2 4.36Å; Y83-W429 AromaticContact CE2-CH2 3.72Å; Y83-W429 HydrophobicContact CE2-CH2 3.72Å; Y83-W429 HydrophobicContact CE2-CZ3 4.44Å; Y83-W429 AromaticContact CG-CH2 3.77Å; Y83-W429 HydrophobicContact CG-CH2 3.77Å; Y83-W429 AromaticContact CG-CZ2 3.89Å; Y83-W429 HydrophobicContact CG-CZ2 3.89Å; Y83-W429 AromaticContact CZ-CH2 3.9Å
84N85.4Confident85.8Confident36 Ų3643.2 Ų43.219%0.19325%0.253CS..Hα-helixtrans-61.6-45.5175.4-164-64000111.4Q65 D69 M77 E80 R81 V86 L87 F88Q65-N84 PolarHBondContact NE2-ND2 3.42Å; Q65-N84 PolarHBondContact NE2-OD1 3.07Å; D69-N84 PolarHBondContact OD1-ND2 3.08Å; M77-N84 HydrophobicContact CE-CB 4.39Å; E80-N84 PolarHBondContact O-N 3.15Å; E80-N84 VanDerWaalsContact O-N 3.08Å; R81-N84 PolarHBondContact O-N 2.9Å; N84-V86 PolarHBondContact O-N 2.91Å; N84-L87 PolarHBondContact O-N 2.92Å; N84-F88 WeakPolarHBondContact O-CB 3.37Å; N84-F88 PolarHBondContact O-N 2.85Å
85S82.4Confident85.6Confident16 Ų1641.5 Ų41.511%0.11225%0.248CC..Hα-helixtrans-60.9-42.6177.4-57.30000113.1R81 K82 G89R81-S85 PolarHBondContact O-N 3.38Å; R81-S85 PolarHBondContact O-OG 3.16Å; R81-S85 VanDerWaalsContact O-OG 3.06Å; K82-S85 PolarHBondContact O-N 3.48Å; S85-G89 PolarHBondContact O-N 2.89Å
86V84.5Confident85.4Confident28 Ų2842.5 Ų42.517%0.1725%0.252CS..Hα-helixtrans-66.4-43.3176.4173.50000110.2K82 Y83 N84 G89 G90 Y300 F304K82-V86 WeakPolarHBondContact O-CG2 3.44Å; K82-V86 PolarHBondContact O-N 3.41Å; Y83-V86 PolarHBondContact O-N 3.45Å; N84-V86 PolarHBondContact O-N 2.91Å; V86-G89 PolarHBondContact O-N 3.16Å; V86-G90 PolarHBondContact O-N 2.89Å; V86-Y300 HydrophobicContact CG1-CE2 3.88Å; V86-Y300 PolarHBondContact O-OH 2.79Å; V86-F304 HydrophobicContact CB-CD1 4.43Å; V86-F304 HydrophobicContact CB-CE1 3.64Å; V86-F304 HydrophobicContact CB-CZ 4.2Å; V86-F304 HydrophobicContact CG1-CD1 4.07Å; V86-F304 HydrophobicContact CG1-CE1 3.37Å; V86-F304 HydrophobicContact CG1-CE2 4.45Å; V86-F304 HydrophobicContact CG1-CZ 3.58Å
87L86.8Confident85.6Confident12 Ų1240.5 Ų40.56%0.06323%0.23CC..Hα-helixtrans-59.4-48177.8-173.363.4000112.8V68 F71 A72 M77 Y83 N84 G90 L91 Y300V68-L87 HydrophobicContact CG1-CB 4.27Å; V68-L87 HydrophobicContact CG1-CD2 3.75Å; V68-L87 HydrophobicContact CG1-CG 3.95Å; F71-L87 HydrophobicContact CD1-CD1 3.8Å; F71-L87 HydrophobicContact CD1-CD2 3.95Å; F71-L87 HydrophobicContact CD1-CG 4.38Å; F71-L87 HydrophobicContact CE1-CD1 3.8Å; A72-L87 HydrophobicContact CB-CD2 3.86Å; M77-L87 HydrophobicContact CE-CD2 3.96Å; M77-L87 HydrophobicContact SD-CB 4.34Å; M77-L87 HydrophobicContact SD-CD2 3.92Å; Y83-L87 VanDerWaalsContact O-CB 3.27Å; Y83-L87 WeakPolarHBondContact O-CB 3.46Å; Y83-L87 PolarHBondContact O-N 2.74Å; N84-L87 PolarHBondContact O-N 2.92Å; L87-G90 PolarHBondContact O-N 3.22Å; L87-L91 PolarHBondContact O-N 3.49Å; L87-Y300 WeakPolarHBondContact CA-OH 3.47Å
88F85.5Confident85.6Confident2 Ų243.3 Ų43.31%0.00924%0.244CC..Hα-helixtrans-62.7-45.7176.4-156.9-50.8000110.5L50 Y61 L64 Q65 V68 N84 G90 L91 V92 F140L50-F88 HydrophobicContact CD1-CB 3.78Å; L50-F88 HydrophobicContact CD1-CD1 3.46Å; L50-F88 VanDerWaalsContact CD1-CD1 3.46Å; L50-F88 HydrophobicContact CD1-CD2 4.46Å; L50-F88 HydrophobicContact CD1-CE1 4.2Å; L50-F88 HydrophobicContact CD1-CG 3.65Å; L50-F88 HydrophobicContact CD2-CD1 3.7Å; L50-F88 HydrophobicContact CD2-CE1 3.52Å; L50-F88 HydrophobicContact CD2-CG 4.36Å; L50-F88 HydrophobicContact CD2-CZ 4.01Å; L50-F88 HydrophobicContact CG-CD1 4.22Å; Y61-F88 HydrophobicContact CD2-CE2 4.41Å; Y61-F88 HydrophobicContact CD2-CZ 4.18Å; Y61-F88 AromaticContact CE2-CE2 3.8Å; Y61-F88 HydrophobicContact CE2-CE2 3.8Å; Y61-F88 AromaticContact CE2-CZ 3.94Å; Y61-F88 HydrophobicContact CE2-CZ 3.94Å; L64-F88 HydrophobicContact CB-CZ 3.83Å; Q65-F88 HydrophobicContact CB-CE2 4.08Å; V68-F88 HydrophobicContact CB-CD2 4.28Å; V68-F88 HydrophobicContact CG1-CB 4.3Å; V68-F88 HydrophobicContact CG1-CD2 4.4Å; V68-F88 HydrophobicContact CG2-CB 4.22Å; V68-F88 HydrophobicContact CG2-CD2 3.75Å; V68-F88 HydrophobicContact CG2-CE2 4.21Å; V68-F88 HydrophobicContact CG2-CG 3.92Å; N84-F88 WeakPolarHBondContact O-CB 3.37Å; N84-F88 PolarHBondContact O-N 2.85Å; F88-G90 VanDerWaalsContact C-N 3.26Å; F88-G90 PolarHBondContact O-N 2.97Å; F88-L91 WeakPolarHBondContact O-CB 3.45Å; F88-L91 PolarHBondContact O-N 3.1Å; F88-L91 VanDerWaalsContact O-N 3.11Å; F88-V92 HydrophobicContact CD1-CG2 3.77Å; F88-V92 HydrophobicContact CE1-CG2 3.79Å; F88-V92 PolarHBondContact O-N 3.38Å; F88-F140 HydrophobicContact CZ-CZ 4.49Å
89G81.5Confident85.8Confident23 Ų2342.1 Ų42.124%0.23724%0.235CC..Hα-helixtrans-56-41.5174.700000112.6S85 V86 V92 G93S85-G89 PolarHBondContact O-N 2.89Å; V86-G89 PolarHBondContact O-N 3.16Å; G89-V92 PolarHBondContact O-N 3.36Å; G89-G93 PolarHBondContact O-N 3.03Å
90G83.5Confident86.2Confident11 Ų1135.9 Ų35.911%0.11319%0.193CC..Hα-helixtrans-60-46.4173.100000112.8V86 L87 F88 V92 G93 S94V86-G90 PolarHBondContact O-N 2.89Å; L87-G90 PolarHBondContact O-N 3.22Å; F88-G90 VanDerWaalsContact C-N 3.26Å; F88-G90 PolarHBondContact O-N 2.97Å; G90-V92 PolarHBondContact O-N 3.36Å; G90-G93 CarbonylContact O-C 3.57Å; G90-G93 PolarHBondContact O-N 2.92Å; G90-S94 PolarHBondContact O-N 3.22Å; G90-S94 PolarHBondContact O-OG 2.96Å
91L84.1Confident86.5Confident63 Ų6332.6 Ų32.633%0.3318%0.178SC..Hα-helixtrans-59.8-45.9176.9-177.268000111.9V68 L87 F88 G93 S94 V95V68-L91 HydrophobicContact CG2-CD2 3.57Å; L87-L91 PolarHBondContact O-N 3.49Å; F88-L91 WeakPolarHBondContact O-CB 3.45Å; F88-L91 PolarHBondContact O-N 3.1Å; F88-L91 VanDerWaalsContact O-N 3.11Å; L91-G93 VanDerWaalsContact C-N 3.32Å; L91-G93 PolarHBondContact O-N 3.44Å; L91-S94 WeakPolarHBondContact O-CB 3.44Å; L91-S94 PolarHBondContact O-N 3.22Å; L91-V95 WeakPolarHBondContact O-CG2 3.29Å; L91-V95 PolarHBondContact O-N 3.42Å
92V82.5Confident87Confident11 Ų1128.8 Ų28.87%0.06717%0.166CC..Hα-helixtrans-62.8-40.9176.6175.10000110.8F46 F88 G89 G90 S94 V95 F96F46-V92 HydrophobicContact CE1-CG1 3.85Å; F46-V92 HydrophobicContact CZ-CG1 4.29Å; F88-V92 HydrophobicContact CD1-CG2 3.77Å; F88-V92 HydrophobicContact CE1-CG2 3.79Å; F88-V92 PolarHBondContact O-N 3.38Å; G89-V92 PolarHBondContact O-N 3.36Å; G90-V92 PolarHBondContact O-N 3.36Å; V92-S94 VanDerWaalsContact C-N 3.34Å; V92-S94 PolarHBondContact O-N 2.99Å; V92-V95 PolarHBondContact O-N 2.92Å; V92-F96 PolarHBondContact O-N 3.14Å
93G84.9Confident87.5Confident35 Ų3527.2 Ų27.236%0.36116%0.16SC..Hα-helixtrans-61.3-39.1173.100000113.3G89 G90 L91 F96 S97G89-G93 PolarHBondContact O-N 3.03Å; G90-G93 CarbonylContact O-C 3.57Å; G90-G93 PolarHBondContact O-N 2.92Å; L91-G93 VanDerWaalsContact C-N 3.32Å; L91-G93 PolarHBondContact O-N 3.44Å; G93-F96 PolarHBondContact O-N 3.47Å; G93-S97 WeakPolarHBondContact O-CB 3.31Å; G93-S97 PolarHBondContact O-N 2.8Å; G93-S97 PolarHBondContact O-OG 3.33Å
94S87.8Confident87.8Confident4 Ų426.6 Ų26.63%0.02816%0.158CC..Hα-helixtrans-66.6-43.2174.8-72.10000111.8G90 L91 V92 F96 S97 I98 A418G90-S94 PolarHBondContact O-N 3.22Å; G90-S94 PolarHBondContact O-OG 2.96Å; L91-S94 WeakPolarHBondContact O-CB 3.44Å; L91-S94 PolarHBondContact O-N 3.22Å; V92-S94 VanDerWaalsContact C-N 3.34Å; V92-S94 PolarHBondContact O-N 2.99Å; S94-F96 VanDerWaalsContact C-N 3.32Å; S94-F96 PolarHBondContact O-N 3.47Å; S94-S97 CarbonylContact O-C 3.58Å; S94-S97 WeakPolarHBondContact O-CB 3.45Å; S94-S97 PolarHBondContact O-N 3.02Å; S94-S97 VanDerWaalsContact O-N 3.1Å; S94-I98 WeakPolarHBondContact O-CG1 3.4Å; S94-I98 PolarHBondContact O-N 2.76Å; S94-A418 PolarHBondContact OG-O 3.04Å
95V87.1Confident87.9Confident59 Ų5924.9 Ų24.936%0.35815%0.149SC..Hα-helixtrans-58.5-45.8173.6172.20000110.7L91 V92 S97 I98 L99L91-V95 WeakPolarHBondContact O-CG2 3.29Å; L91-V95 PolarHBondContact O-N 3.42Å; V92-V95 PolarHBondContact O-N 2.92Å; V95-S97 VanDerWaalsContact C-N 3.25Å; V95-S97 PolarHBondContact O-N 3.29Å; V95-I98 PolarHBondContact O-N 2.83Å; V95-L99 HydrophobicContact CG1-CD1 4.46Å; V95-L99 WeakPolarHBondContact O-CG 3.47Å; V95-L99 PolarHBondContact O-N 3.46Å
96F88.6Confident88.3Confident22 Ų2228.3 Ų28.310%0.09617%0.165CC..Hα-helixtrans-60.7-36.5176.4-168.2-102.2000112.4F39 V92 G93 S94 Q100 G151 K154F39-F96 HydrophobicContact CD2-CE1 4.38Å; F39-F96 HydrophobicContact CD2-CZ 4.11Å; F39-F96 HydrophobicContact CE2-CD1 4.17Å; F39-F96 AromaticContact CE2-CE1 3.37Å; F39-F96 HydrophobicContact CE2-CE1 3.37Å; F39-F96 HydrophobicContact CE2-CE2 4.09Å; F39-F96 AromaticContact CE2-CZ 3.36Å; F39-F96 HydrophobicContact CE2-CZ 3.36Å; F39-F96 HydrophobicContact CZ-CD1 4.13Å; F39-F96 AromaticContact CZ-CE1 3.59Å; F39-F96 HydrophobicContact CZ-CE1 3.59Å; F39-F96 HydrophobicContact CZ-CZ 4.08Å; V92-F96 PolarHBondContact O-N 3.14Å; G93-F96 PolarHBondContact O-N 3.47Å; S94-F96 VanDerWaalsContact C-N 3.32Å; S94-F96 PolarHBondContact O-N 3.47Å; F96-Q100 PolarHBondContact O-N 3.47Å; F96-G151 VanDerWaalsContact CE2-N 3.27Å; F96-K154 HydrophobicContact CE1-CG 4.38Å; F96-K154 HydrophobicContact CZ-CB 4.31Å; F96-K154 HydrophobicContact CZ-CD 4.34Å; F96-K154 HydrophobicContact CZ-CG 4.19Å
97S92.3Very high88.7Confident13 Ų1327.6 Ų27.69%0.09116%0.161CC..Hα-helixtrans-71.8-35.1176.1-59.60000112.7G93 S94 V95 Q100 F101 A414G93-S97 WeakPolarHBondContact O-CB 3.31Å; G93-S97 PolarHBondContact O-N 2.8Å; G93-S97 PolarHBondContact O-OG 3.33Å; S94-S97 CarbonylContact O-C 3.58Å; S94-S97 WeakPolarHBondContact O-CB 3.45Å; S94-S97 PolarHBondContact O-N 3.02Å; S94-S97 VanDerWaalsContact O-N 3.1Å; V95-S97 VanDerWaalsContact C-N 3.25Å; V95-S97 PolarHBondContact O-N 3.29Å; S97-Q100 WeakPolarHBondContact O-CB 3.45Å; S97-Q100 PolarHBondContact O-N 2.81Å; S97-F101 PolarHBondContact O-N 3.46Å; S97-A414 WeakPolarHBondContact CB-O 3.47Å; S97-A414 WeakPolarHBondContact O-CB 3.47Å
98I93.3Very high88.9Confident74 Ų7427 Ų2738%0.37916%0.158SC..Hα-helixtrans-64.3-42.5173.6-69.4165.8000110.8S94 V95 Q100 F101 F102 A418S94-I98 WeakPolarHBondContact O-CG1 3.4Å; S94-I98 PolarHBondContact O-N 2.76Å; V95-I98 PolarHBondContact O-N 2.83Å; I98-Q100 VanDerWaalsContact C-N 3.3Å; I98-Q100 PolarHBondContact O-N 2.86Å; I98-F101 WeakPolarHBondContact O-CB 3.33Å; I98-F101 PolarHBondContact O-N 3.39Å; I98-F101 VanDerWaalsContact O-N 3.15Å; I98-F102 HydrophobicContact CG2-CD2 4Å; I98-F102 HydrophobicContact CG2-CE2 3.58Å; I98-F102 WeakPolarHBondContact O-CD2 3.4Å; I98-F102 PolarHBondContact O-N 3.46Å; I98-A418 HydrophobicContact CD1-CB 4.5Å; I98-A418 HydrophobicContact CG1-CB 3.74Å
99L93.6Very high89.1Confident33 Ų3327.4 Ų27.417%0.17316%0.162CC..Hα-helixtrans-61.4-41.4175.9-66.2169.2000111.6V95 F101 F102 S103 I148 I152V95-L99 HydrophobicContact CG1-CD1 4.46Å; V95-L99 WeakPolarHBondContact O-CG 3.47Å; V95-L99 PolarHBondContact O-N 3.46Å; L99-F101 VanDerWaalsContact C-N 3.34Å; L99-F102 PolarHBondContact O-N 3.26Å; L99-S103 WeakPolarHBondContact O-CB 3.33Å; L99-S103 PolarHBondContact O-N 2.83Å; L99-S103 PolarHBondContact O-OG 2.98Å; L99-S103 VanDerWaalsContact O-OG 3.13Å; L99-I148 HydrophobicContact CD1-CB 4.26Å; L99-I148 HydrophobicContact CD1-CG1 4.19Å; L99-I148 HydrophobicContact CD1-CG2 4.36Å; L99-I148 HydrophobicContact CD2-CG2 4.4Å; L99-I152 HydrophobicContact CD2-CG1 4.2Å
100Q92.8Very high89.6Confident11 Ų1127.6 Ų27.65%0.05116%0.158CC..Hα-helixtrans-65.3-35174-77.6176.452.200113.5F96 S97 I98 F102 S103 S104 K154 R410 A414F96-Q100 PolarHBondContact O-N 3.47Å; S97-Q100 WeakPolarHBondContact O-CB 3.45Å; S97-Q100 PolarHBondContact O-N 2.81Å; I98-Q100 VanDerWaalsContact C-N 3.3Å; I98-Q100 PolarHBondContact O-N 2.86Å; Q100-F102 VanDerWaalsContact C-N 3.29Å; Q100-F102 PolarHBondContact O-N 3.41Å; Q100-S103 WeakPolarHBondContact CA-OG 3.37Å; Q100-S103 PolarHBondContact O-N 3.41Å; Q100-S104 VanDerWaalsContact O-CB 3.23Å; Q100-S104 WeakPolarHBondContact O-CB 3.35Å; Q100-S104 PolarHBondContact O-N 3.08Å; Q100-S104 PolarHBondContact O-OG 3.38Å; Q100-K154 HydrophobicContact CG-CB 4.02Å; Q100-R410 VanDerWaalsContact OE1-CZ 3.25Å; Q100-A414 HydrophobicContact CB-CB 3.82Å
101F93.1Very high90Very high7 Ų727 Ų273%0.03115%0.153CC..Hα-helixtrans-57.7-45.2176.6164.4-104.5000110.7S97 I98 L99 P105 P257 L260 S411 A414 L415S97-F101 PolarHBondContact O-N 3.46Å; I98-F101 WeakPolarHBondContact O-CB 3.33Å; I98-F101 PolarHBondContact O-N 3.39Å; I98-F101 VanDerWaalsContact O-N 3.15Å; L99-F101 VanDerWaalsContact C-N 3.34Å; F101-P105 WeakPolarHBondContact O-CD 3.42Å; F101-P257 HydrophobicContact CE1-CG 4.41Å; F101-P257 HydrophobicContact CZ-CB 4.28Å; F101-P257 HydrophobicContact CZ-CG 3.81Å; F101-L260 HydrophobicContact CD2-CD1 4.2Å; F101-L260 HydrophobicContact CE2-CD1 3.28Å; F101-L260 HydrophobicContact CZ-CD1 3.62Å; F101-S411 WeakPolarHBondContact CD2-O 3.32Å; F101-S411 WeakPolarHBondContact CD2-OG 3.32Å; F101-S411 WeakPolarHBondContact CE2-OG 3.2Å; F101-S411 WeakPolarHBondContact O-CB 3.48Å; F101-S411 PolarHBondContact O-OG 2.84Å; F101-A414 HydrophobicContact CB-CB 4.09Å; F101-L415 HydrophobicContact CD2-CB 3.62Å; F101-L415 HydrophobicContact CD2-CD1 4.33Å; F101-L415 HydrophobicContact CD2-CD2 4.43Å; F101-L415 HydrophobicContact CD2-CG 4.34Å; F101-L415 HydrophobicContact CE2-CB 3.98Å; F101-L415 HydrophobicContact CE2-CD1 4.36Å; F101-L415 HydrophobicContact CE2-CD2 3.95Å; F101-L415 HydrophobicContact CE2-CG 4.33Å; F101-L415 HydrophobicContact CG-CB 4.31Å; F101-L415 HydrophobicContact CG-CD1 4.5Å; F101-L415 HydrophobicContact CZ-CD2 4.46Å
102F90.9Very high90.3Very high90 Ų9024 Ų2440%0.39514%0.137SC..Hα-helixtrans-78-37.3178.1-64.1-61000113.6I98 L99 Q100 L255I98-F102 HydrophobicContact CG2-CD2 4Å; I98-F102 HydrophobicContact CG2-CE2 3.58Å; I98-F102 WeakPolarHBondContact O-CD2 3.4Å; I98-F102 PolarHBondContact O-N 3.46Å; L99-F102 PolarHBondContact O-N 3.26Å; Q100-F102 VanDerWaalsContact C-N 3.29Å; Q100-F102 PolarHBondContact O-N 3.41Å; F102-L255 HydrophobicContact CB-CD2 3.89Å; F102-L255 HydrophobicContact CD1-CB 4.33Å; F102-L255 HydrophobicContact CD1-CD2 3.51Å; F102-L255 HydrophobicContact CD1-CG 4.49Å; F102-L255 HydrophobicContact CE1-CD2 4.45Å; F102-L255 HydrophobicContact CG-CD2 4.13Å
103S91.7Very high90.6Very high8 Ų824.3 Ų24.36%0.05614%0.139CC..Hα-helixtrans-77.3-37.8-175.568.60000113.5L99 Q100 L106 T107 G151 I152L99-S103 WeakPolarHBondContact O-CB 3.33Å; L99-S103 PolarHBondContact O-N 2.83Å; L99-S103 PolarHBondContact O-OG 2.98Å; L99-S103 VanDerWaalsContact O-OG 3.13Å; Q100-S103 WeakPolarHBondContact CA-OG 3.37Å; Q100-S103 PolarHBondContact O-N 3.41Å; S103-L106 PolarHBondContact O-N 3.09Å; S103-T107 PolarHBondContact O-N 3.19Å; S103-T107 PolarHBondContact O-OG1 2.83Å; S103-G151 PolarHBondContact OG-O 3.15Å; S103-I152 VanDerWaalsContact CB-O 3.26Å; S103-I152 WeakPolarHBondContact CB-O 3.37Å; S103-I152 PolarHBondContact OG-O 3.31Å
104S91.3Very high90.9Very high0 Ų026.8 Ų26.80%014%0.144CC..Hα-helixtrans-59.9-45.1-171.2-58.30000114.6Q100 G108Q100-S104 VanDerWaalsContact O-CB 3.23Å; Q100-S104 WeakPolarHBondContact O-CB 3.35Å; Q100-S104 PolarHBondContact O-N 3.08Å; Q100-S104 PolarHBondContact O-OG 3.38Å; S104-G108 PolarHBondContact O-N 3.29Å
105P88.6Confident91.1Very high0 Ų026.6 Ų26.60%014%0.142CC..Hα-helixtrans-68.1-39.1177.9-19.234.5000111.8F101 G108 A109 L254 L260 S411F101-P105 WeakPolarHBondContact O-CD 3.42Å; P105-G108 PolarHBondContact O-N 2.85Å; P105-A109 WeakPolarHBondContact O-CB 3.35Å; P105-A109 PolarHBondContact O-N 3.47Å; P105-L254 HydrophobicContact CB-CB 3.99Å; P105-L254 HydrophobicContact CB-CD2 3.62Å; P105-L254 HydrophobicContact CB-CG 4.31Å; P105-L260 HydrophobicContact CB-CD2 4.27Å; P105-L260 HydrophobicContact CG-CD2 4Å; P105-S411 WeakPolarHBondContact CG-OG 3.33Å
106L90.7Very high91.5Very high88 Ų8823.9 Ų23.946%0.46113%0.125SC..Hα-helixtrans-64.3-50.2178.8-178.463.3000110.9S103 G108 A109 V110S103-L106 PolarHBondContact O-N 3.09Å; L106-G108 VanDerWaalsContact C-N 3.28Å; L106-G108 PolarHBondContact O-N 2.97Å; L106-A109 PolarHBondContact O-N 3.2Å; L106-V110 HydrophobicContact CD1-CG2 4.3Å; L106-V110 HydrophobicContact CG-CG2 4.48Å; L106-V110 WeakPolarHBondContact O-CB 3.43Å; L106-V110 VanDerWaalsContact O-CG2 3.26Å; L106-V110 WeakPolarHBondContact O-CG2 3.28Å; L106-V110 PolarHBondContact O-N 3.37Å
107T92.4Very high91.8Very high13 Ų1326.8 Ų26.88%0.0814%0.136CC..Hα-helixtrans-60-40.7176.5-51.60000111.3S103 V110 S111 V119 T123 L159S103-T107 PolarHBondContact O-N 3.19Å; S103-T107 PolarHBondContact O-OG1 2.83Å; T107-V110 PolarHBondContact O-N 3.02Å; T107-S111 WeakPolarHBondContact O-CB 3.15Å; T107-S111 PolarHBondContact O-N 3.28Å; T107-S111 PolarHBondContact O-OG 3.07Å; T107-V119 HydrophobicContact CG2-CG1 3.59Å; T107-T123 HydrophobicContact CG2-CG2 3.78Å; T107-L159 HydrophobicContact CG2-CD1 3.67Å; T107-L159 HydrophobicContact CG2-CD2 4.09Å; T107-L159 HydrophobicContact CG2-CG 3.88Å
108G91.4Very high92Very high0 Ų029.1 Ų29.10%015%0.151CC..Hα-helixtrans-57.4-51.8173.900000112.3S104 P105 L106 V110 S111 D112 G403S104-G108 PolarHBondContact O-N 3.29Å; P105-G108 PolarHBondContact O-N 2.85Å; L106-G108 VanDerWaalsContact C-N 3.28Å; L106-G108 PolarHBondContact O-N 2.97Å; G108-V110 PolarHBondContact O-N 3.42Å; G108-S111 PolarHBondContact O-N 3.38Å; G108-S111 PolarHBondContact O-OG 3.06Å; G108-D112 PolarHBondContact O-N 3.07Å; G108-D112 VanDerWaalsContact O-N 3.14Å; G108-G403 WeakPolarHBondContact CA-O 3.45Å
109A88.9Confident92.1Very high11 Ų1125.7 Ų25.79%0.09113%0.133CC..Hα-helixtrans-64-40.3179.400000113.3P105 L106 S111 D112 C113 L254 R404P105-A109 WeakPolarHBondContact O-CB 3.35Å; P105-A109 PolarHBondContact O-N 3.47Å; L106-A109 PolarHBondContact O-N 3.2Å; A109-S111 VanDerWaalsContact C-N 3.29Å; A109-S111 PolarHBondContact O-N 3.46Å; A109-D112 PolarHBondContact O-N 3.45Å; A109-C113 PolarHBondContact O-SG 3.1Å; A109-C113 VanDerWaalsContact O-SG 3.38Å; A109-L254 HydrophobicContact CB-CD1 3.75Å; A109-R404 HydrophobicContact CB-CG 3.87Å
110V91.1Very high92.3Very high26 Ų2624.4 Ų24.416%0.15813%0.126CC..Hα-helixtrans-62.7-38.8175.6172.80000110.5L106 T107 G108 D112 C113 L114 V119 V244L106-V110 HydrophobicContact CD1-CG2 4.3Å; L106-V110 HydrophobicContact CG-CG2 4.48Å; L106-V110 WeakPolarHBondContact O-CB 3.43Å; L106-V110 VanDerWaalsContact O-CG2 3.26Å; L106-V110 WeakPolarHBondContact O-CG2 3.28Å; L106-V110 PolarHBondContact O-N 3.37Å; T107-V110 PolarHBondContact O-N 3.02Å; G108-V110 PolarHBondContact O-N 3.42Å; V110-D112 PolarHBondContact O-N 3.16Å; V110-C113 PolarHBondContact O-N 2.9Å; V110-C113 VanDerWaalsContact O-N 3.15Å; V110-L114 HydrophobicContact CG1-CD1 3.61Å; V110-L114 HydrophobicContact CG1-CG 4.14Å; V110-L114 PolarHBondContact O-N 3.37Å; V110-V119 HydrophobicContact CG1-CG1 4.31Å; V110-V119 HydrophobicContact CG1-CG2 3.91Å; V110-V244 HydrophobicContact CG2-CG1 4.4Å
111S93.1Very high92.5Very high0 Ų025.3 Ų25.30%013%0.131CC..Hα-helixtrans-70.4-27177.576.20000114.6T107 G108 A109 C113 G115 R116 L159T107-S111 WeakPolarHBondContact O-CB 3.15Å; T107-S111 PolarHBondContact O-N 3.28Å; T107-S111 PolarHBondContact O-OG 3.07Å; G108-S111 PolarHBondContact O-N 3.38Å; G108-S111 PolarHBondContact O-OG 3.06Å; A109-S111 VanDerWaalsContact C-N 3.29Å; A109-S111 PolarHBondContact O-N 3.46Å; S111-C113 PolarHBondContact O-N 3.24Å; S111-G115 CarbonylContact O-C 3.56Å; S111-G115 VanDerWaalsContact O-C 3.24Å; S111-G115 VanDerWaalsContact O-CA 3.26Å; S111-G115 WeakPolarHBondContact O-CA 3.41Å; S111-G115 PolarHBondContact O-N 3.35Å; S111-R116 VanDerWaalsContact C-NH1 3.33Å; S111-R116 PolarHBondContact O-NH1 3.29Å; S111-R116 PolarHBondContact OG-NH1 3.32Å; S111-L159 WeakPolarHBondContact OG-CD2 3.44Å
112D90.4Very high92.7Very high0 Ų030.5 Ų30.50%016%0.157CC..Hα-helixtrans-66.7-19.4172-76.2-27.8000112.3G108 A109 V110 R116 V241 S400 G403 R404G108-D112 PolarHBondContact O-N 3.07Å; G108-D112 VanDerWaalsContact O-N 3.14Å; A109-D112 PolarHBondContact O-N 3.45Å; V110-D112 PolarHBondContact O-N 3.16Å; D112-R116 IonicContact OD1-CZ 3.88Å; D112-R116 IonicContact OD1-NH1 3.67Å; D112-R116 PolarHBondContact OD1-NH1 3.07Å; D112-R116 IonicContact OD1-NH2 3.22Å; D112-R116 PolarHBondContact OD1-NH2 3.42Å; D112-V241 HydrophobicContact CB-CG2 4.42Å; D112-V241 PolarHBondContact O-N 3.43Å; D112-S400 VanDerWaalsContact CB-O 3.23Å; D112-S400 WeakPolarHBondContact CB-O 3.34Å; D112-G403 WeakPolarHBondContact OD1-CA 3.48Å; D112-G403 PolarHBondContact OD1-N 3.31Å; D112-G403 WeakPolarHBondContact OD2-CA 3.44Å; D112-G403 PolarHBondContact OD2-N 3.07Å; D112-R404 WeakPolarHBondContact OD2-CG 3.32Å; D112-R404 PolarHBondContact OD2-N 2.99Å
113C88.4Confident92.9Very high16 Ų1626.5 Ų26.511%0.10814%0.14CC..Hα-helixtrans-103.1-45.4179.9-52.70000112.6A109 V110 S111 R240 V244A109-C113 PolarHBondContact O-SG 3.1Å; A109-C113 VanDerWaalsContact O-SG 3.38Å; V110-C113 PolarHBondContact O-N 2.9Å; V110-C113 VanDerWaalsContact O-N 3.15Å; S111-C113 PolarHBondContact O-N 3.24Å; C113-R240 WeakPolarHBondContact O-CD 3.33Å; C113-V244 HydrophobicContact CB-CB 4.47Å; C113-V244 HydrophobicContact CB-CG2 3.27Å; C113-V244 VanDerWaalsContact SG-CG2 3.57Å
114L90.9Very high93.2Very high88 Ų8826.1 Ų26.146%0.46114%0.137SC..Hα-helixtrans-88.7-16.1-176-61.2-176.2000113.5V110 V119 R240V110-L114 HydrophobicContact CG1-CD1 3.61Å; V110-L114 HydrophobicContact CG1-CG 4.14Å; V110-L114 PolarHBondContact O-N 3.37Å; L114-V119 HydrophobicContact CB-CG2 3.91Å; L114-V119 HydrophobicContact CD1-CG2 4.33Å; L114-R240 PolarHBondContact O-NH1 2.91Å
115G92.7Very high93.5Very high0 Ų031 Ų310%016%0.161CC..  trans99.9163-169.300000112.3S111 V119S111-G115 CarbonylContact O-C 3.56Å; S111-G115 VanDerWaalsContact O-C 3.24Å; S111-G115 VanDerWaalsContact O-CA 3.26Å; S111-G115 WeakPolarHBondContact O-CA 3.41Å; S111-G115 PolarHBondContact O-N 3.35Å; G115-V119 WeakPolarHBondContact O-CG2 3.14Å
116R95.2Very high93.9Very high1 Ų131.6 Ų31.60%0.00417%0.168CC..Hα-helixtrans-74.5-44.2-177.2-55.4-54.9-178.6-144.8-10.3111.6S111 D112 V119 I120 I163 D166 E233 T234 L235S111-R116 VanDerWaalsContact C-NH1 3.33Å; S111-R116 PolarHBondContact O-NH1 3.29Å; S111-R116 PolarHBondContact OG-NH1 3.32Å; D112-R116 IonicContact OD1-CZ 3.88Å; D112-R116 IonicContact OD1-NH1 3.67Å; D112-R116 PolarHBondContact OD1-NH1 3.07Å; D112-R116 IonicContact OD1-NH2 3.22Å; D112-R116 PolarHBondContact OD1-NH2 3.42Å; R116-V119 PolarHBondContact O-N 2.84Å; R116-I120 WeakPolarHBondContact O-CG2 3.49Å; R116-I120 PolarHBondContact O-N 3.02Å; R116-I163 HydrophobicContact CB-CD1 4.15Å; R116-I163 HydrophobicContact CB-CG1 3.64Å; R116-I163 HydrophobicContact CG-CG1 3.86Å; R116-D166 WeakPolarHBondContact CG-OD2 3.22Å; R116-D166 IonicContact CZ-OD1 3.64Å; R116-D166 IonicContact CZ-OD2 3.49Å; R116-D166 IonicContact NE-OD1 3.98Å; R116-D166 IonicContact NE-OD2 3.97Å; R116-D166 PolarHBondContact NE-OD2 3.3Å; R116-D166 IonicContact NH2-OD1 2.66Å; R116-D166 PolarHBondContact NH2-OD1 3.49Å; R116-D166 IonicContact NH2-OD2 2.64Å; R116-E233 PolarHBondContact N-OE1 3.27Å; R116-E233 PolarHBondContact N-OE2 3.07Å; R116-T234 VanDerWaalsContact CG-OG1 3.28Å; R116-T234 WeakPolarHBondContact CG-OG1 2.97Å; R116-L235 HydrophobicContact CG-CB 4.21Å
117R95.8Very high94.2Very high84 Ų8427.5 Ų27.532%0.31715%0.147SC..Hα-helixtrans-65.3-45.8-172.7-176.5-175.7178.9-162.7-2.8113.1V119 I120 L121 F228 L231 E233R117-V119 VanDerWaalsContact C-N 3.34Å; R117-V119 PolarHBondContact O-N 2.91Å; R117-I120 VanDerWaalsContact O-CG2 3.26Å; R117-I120 WeakPolarHBondContact O-CG2 3.28Å; R117-L121 HydrophobicContact CG-CD1 4.22Å; R117-L121 VanDerWaalsContact O-CG 3.3Å; R117-L121 WeakPolarHBondContact O-CG 3.3Å; R117-L121 PolarHBondContact O-N 3.39Å; R117-F228 PolarHBondContact NH2-O 3.18Å; R117-L231 VanDerWaalsContact CD-O 3.23Å; R117-L231 WeakPolarHBondContact CD-O 3.22Å; R117-L231 PolarHBondContact NE-O 2.69Å; R117-E233 PolarHBondContact N-OE2 3.37Å
118P95.9Very high94.5Very high62 Ų6228.3 Ų28.340%0.40315%0.15SC..Hα-helixtrans-63.7-39.7178.8-23.935.6000112.7L121 M122 E233P118-L121 PolarHBondContact O-N 3.36Å; P118-M122 PolarHBondContact O-N 3.41Å; P118-E233 VanDerWaalsContact CD-OE2 3.31Å; P118-E233 WeakPolarHBondContact CD-OE2 3.38Å
119V96.1Very high94.8Very high2 Ų230.3 Ų30.31%0.01217%0.167CC..Hα-helixtrans-74.7-37-175.5-1720000111.3T107 V110 L114 G115 R116 R117 L121 M122 T123 L159T107-V119 HydrophobicContact CG2-CG1 3.59Å; V110-V119 HydrophobicContact CG1-CG1 4.31Å; V110-V119 HydrophobicContact CG1-CG2 3.91Å; L114-V119 HydrophobicContact CB-CG2 3.91Å; L114-V119 HydrophobicContact CD1-CG2 4.33Å; G115-V119 WeakPolarHBondContact O-CG2 3.14Å; R116-V119 PolarHBondContact O-N 2.84Å; R117-V119 VanDerWaalsContact C-N 3.34Å; R117-V119 PolarHBondContact O-N 2.91Å; V119-L121 VanDerWaalsContact C-N 3.34Å; V119-M122 HydrophobicContact CG1-CE 4.24Å; V119-M122 WeakPolarHBondContact O-CB 3.11Å; V119-M122 PolarHBondContact O-N 3.39Å; V119-T123 PolarHBondContact O-N 3.03Å; V119-T123 PolarHBondContact O-OG1 2.91Å; V119-L159 HydrophobicContact CB-CD1 4.09Å; V119-L159 HydrophobicContact CG1-CD1 3.83Å; V119-L159 HydrophobicContact CG1-CD2 4.41Å
120I96.6Very high95.2Very high5 Ų529.9 Ų29.93%0.02616%0.163CC..Hα-helixtrans-66-38.8175.2-163.9170.4000111.2R116 R117 M122 T123 V124 N156 L159 I163 I227 L231R116-I120 WeakPolarHBondContact O-CG2 3.49Å; R116-I120 PolarHBondContact O-N 3.02Å; R117-I120 VanDerWaalsContact O-CG2 3.26Å; R117-I120 WeakPolarHBondContact O-CG2 3.28Å; I120-M122 PolarHBondContact O-N 3.06Å; I120-T123 VanDerWaalsContact CA-OG1 3.31Å; I120-T123 WeakPolarHBondContact CA-OG1 3.26Å; I120-T123 PolarHBondContact O-N 2.84Å; I120-T123 PolarHBondContact O-OG1 3.26Å; I120-V124 WeakPolarHBondContact O-CG2 3.18Å; I120-V124 PolarHBondContact O-N 3.03Å; I120-N156 HydrophobicContact CG1-CB 4.15Å; I120-L159 VanDerWaalsContact CA-CD1 3.49Å; I120-L159 HydrophobicContact CB-CB 4.43Å; I120-L159 HydrophobicContact CB-CD1 3.78Å; I120-L159 HydrophobicContact CD1-CB 4.45Å; I120-L159 HydrophobicContact CG1-CB 4.49Å; I120-L159 HydrophobicContact CG1-CD1 4.29Å; I120-I163 HydrophobicContact CD1-CD1 4.11Å; I120-I227 HydrophobicContact CD1-CD1 4.22Å; I120-I227 HydrophobicContact CG1-CD1 4.28Å; I120-I227 HydrophobicContact CG2-CG2 3.79Å; I120-L231 HydrophobicContact CD1-CD2 4.43Å; I120-L231 HydrophobicContact CG2-CD2 3.67Å
121L97.5Very high95.5Very high30 Ų3028.9 Ų28.916%0.15716%0.156CC..Hα-helixtrans-60.8-43.5173.3-71170.1000111.7R117 P118 V119 T123 V124 M125 L224 I227 F228R117-L121 HydrophobicContact CG-CD1 4.22Å; R117-L121 VanDerWaalsContact O-CG 3.3Å; R117-L121 WeakPolarHBondContact O-CG 3.3Å; R117-L121 PolarHBondContact O-N 3.39Å; P118-L121 PolarHBondContact O-N 3.36Å; V119-L121 VanDerWaalsContact C-N 3.34Å; L121-T123 VanDerWaalsContact C-N 3.33Å; L121-T123 PolarHBondContact O-N 3.26Å; L121-V124 PolarHBondContact O-N 3.38Å; L121-M125 WeakPolarHBondContact O-CG 3.34Å; L121-M125 PolarHBondContact O-N 3.35Å; L121-L224 HydrophobicContact CD2-CD1 3.79Å; L121-I227 HydrophobicContact CD2-CB 4.18Å; L121-I227 HydrophobicContact CD2-CG2 3.64Å; L121-I227 HydrophobicContact CG-CG2 4.08Å; L121-F228 HydrophobicContact CD1-CD2 4.13Å; L121-F228 HydrophobicContact CD2-CB 4Å; L121-F228 HydrophobicContact CD2-CD2 4.5Å
122M96.6Very high95.8Very high116 Ų11630.8 Ų30.857%0.57117%0.173SC*.Hα-helixtrans-60.3-41.2175.5-174.1-177.572.600112.1P118 V119 I120 M125 G126P118-M122 PolarHBondContact O-N 3.41Å; V119-M122 HydrophobicContact CG1-CE 4.24Å; V119-M122 WeakPolarHBondContact O-CB 3.11Å; V119-M122 PolarHBondContact O-N 3.39Å; I120-M122 PolarHBondContact O-N 3.06Å; M122-M125 PolarHBondContact O-N 2.97Å; M122-G126 PolarHBondContact O-N 3.25Å
123T96Very high96.1Very high6 Ų633.2 Ų33.24%0.03719%0.185CC..Hα-helixtrans-64.5-41.4175.951.80000112.4T107 V119 I120 L121 G126 L127 S153 N156 L159T107-T123 HydrophobicContact CG2-CG2 3.78Å; V119-T123 PolarHBondContact O-N 3.03Å; V119-T123 PolarHBondContact O-OG1 2.91Å; I120-T123 VanDerWaalsContact CA-OG1 3.31Å; I120-T123 WeakPolarHBondContact CA-OG1 3.26Å; I120-T123 PolarHBondContact O-N 2.84Å; I120-T123 PolarHBondContact O-OG1 3.26Å; L121-T123 VanDerWaalsContact C-N 3.33Å; L121-T123 PolarHBondContact O-N 3.26Å; T123-G126 PolarHBondContact O-N 2.85Å; T123-L127 PolarHBondContact O-N 3Å; T123-L127 VanDerWaalsContact O-N 3.08Å; T123-S153 VanDerWaalsContact CB-O 3.27Å; T123-S153 WeakPolarHBondContact CB-O 3.48Å; T123-S153 WeakPolarHBondContact O-CB 3.23Å; T123-N156 WeakPolarHBondContact OG1-CB 3.47Å; T123-L159 HydrophobicContact CG2-CD1 4.27Å
124V97.1Very high96.5Very high0 Ų032.5 Ų32.50%018%0.18CC..Hα-helixtrans-68.1-36.8178.8178.50000111.6I120 L121 G126 L127 I128 A220 L224 I227I120-V124 WeakPolarHBondContact O-CG2 3.18Å; I120-V124 PolarHBondContact O-N 3.03Å; L121-V124 PolarHBondContact O-N 3.38Å; V124-G126 VanDerWaalsContact C-N 3.28Å; V124-G126 PolarHBondContact O-N 3.3Å; V124-L127 WeakPolarHBondContact O-CA 3.36Å; V124-L127 WeakPolarHBondContact O-CB 3.3Å; V124-L127 PolarHBondContact O-N 3.45Å; V124-I128 WeakPolarHBondContact O-CG1 3.33Å; V124-I128 PolarHBondContact O-N 3.4Å; V124-A220 WeakPolarHBondContact CG1-O 3.36Å; V124-L224 HydrophobicContact CB-CD1 4.12Å; V124-L224 HydrophobicContact CG1-CB 3.71Å; V124-L224 HydrophobicContact CG1-CD1 4.01Å; V124-L224 HydrophobicContact CG1-CG 4.49Å; V124-I227 HydrophobicContact CG2-CD1 3.85Å
125M97.6Very high96.7Very high102 Ų10228.8 Ų28.850%0.50216%0.162SC..Hα-helixtrans-58.1-40.7171.7-72.8-60.9-63.100112.4L121 M122 L127 I128 A129 L224L121-M125 WeakPolarHBondContact O-CG 3.34Å; L121-M125 PolarHBondContact O-N 3.35Å; M122-M125 PolarHBondContact O-N 2.97Å; M125-L127 VanDerWaalsContact C-N 3.34Å; M125-I128 WeakPolarHBondContact O-CB 3.31Å; M125-I128 PolarHBondContact O-N 3.45Å; M125-I128 HydrophobicContact SD-CD1 4.18Å; M125-A129 PolarHBondContact O-N 3.15Å; M125-A129 VanDerWaalsContact O-N 3.07Å; M125-L224 HydrophobicContact CG-CD1 3.97Å; M125-L224 HydrophobicContact SD-CD1 3.83Å; M125-L224 HydrophobicContact SD-CD2 3.42Å; M125-L224 WeakPolarHBondContact SD-CD2 3.25Å; M125-L224 HydrophobicContact SD-CG 4.28Å
126G97.3Very high96.8Very high14 Ų1431.5 Ų31.514%0.14419%0.185CC..Hα-helixtrans-66.4-3417400000113.3M122 T123 V124 A129 S130 I149 S153M122-G126 PolarHBondContact O-N 3.25Å; T123-G126 PolarHBondContact O-N 2.85Å; V124-G126 VanDerWaalsContact C-N 3.28Å; V124-G126 PolarHBondContact O-N 3.3Å; G126-A129 PolarHBondContact O-N 3.47Å; G126-S130 WeakPolarHBondContact O-CB 3.44Å; G126-S130 PolarHBondContact O-N 3.02Å; G126-I149 WeakPolarHBondContact O-CG2 3.47Å; G126-S153 WeakPolarHBondContact CA-OG 3.41Å
127L96.8Very high96.7Very high2 Ų231.5 Ų31.51%0.0119%0.185CC..Hα-helixtrans-66.8-39.1172.7-66.5171.7000112.4D35 T123 V124 M125 A129 S130 Y131 K154D35-L127 WeakPolarHBondContact OD1-CD1 3.27Å; T123-L127 PolarHBondContact O-N 3Å; T123-L127 VanDerWaalsContact O-N 3.08Å; V124-L127 WeakPolarHBondContact O-CA 3.36Å; V124-L127 WeakPolarHBondContact O-CB 3.3Å; V124-L127 PolarHBondContact O-N 3.45Å; M125-L127 VanDerWaalsContact C-N 3.34Å; L127-A129 VanDerWaalsContact C-N 3.35Å; L127-S130 WeakPolarHBondContact O-CB 3.36Å; L127-S130 PolarHBondContact O-N 3.38Å; L127-Y131 HydrophobicContact CB-CE2 4.29Å; L127-Y131 VanDerWaalsContact O-CD2 3.22Å; L127-Y131 WeakPolarHBondContact O-CD2 3.12Å; L127-Y131 PolarHBondContact O-N 3.2Å; L127-K154 HydrophobicContact CD1-CD 4.48Å; L127-K154 HydrophobicContact CD2-CD 3.87Å
128I98.4Very high96.3Very high29 Ų2933.4 Ų33.415%0.14919%0.192CC..Hα-helixtrans-58.7-48172.4-68.9169.3000110.1V124 M125 S130 Y131 A132 L217 A220 V221 L224V124-I128 WeakPolarHBondContact O-CG1 3.33Å; V124-I128 PolarHBondContact O-N 3.4Å; M125-I128 WeakPolarHBondContact O-CB 3.31Å; M125-I128 PolarHBondContact O-N 3.45Å; M125-I128 HydrophobicContact SD-CD1 4.18Å; I128-S130 VanDerWaalsContact C-N 3.32Å; I128-S130 PolarHBondContact O-N 3.08Å; I128-Y131 PolarHBondContact O-N 3.35Å; I128-A132 WeakPolarHBondContact O-CB 3.45Å; I128-A132 PolarHBondContact O-N 3.24Å; I128-L217 HydrophobicContact CB-CD1 4.36Å; I128-L217 HydrophobicContact CG2-CD1 3.72Å; I128-L217 WeakPolarHBondContact O-CD1 3.25Å; I128-A220 HydrophobicContact CG1-CB 3.68Å; I128-V221 HydrophobicContact CD1-CG2 4Å; I128-V221 HydrophobicContact CG1-CG2 4.15Å; I128-V221 HydrophobicContact CG2-CG2 4.34Å; I128-L224 HydrophobicContact CD1-CB 3.96Å; I128-L224 HydrophobicContact CD1-CD2 3.72Å; I128-L224 HydrophobicContact CD1-CG 4.33Å
129A98.1Very high96Very high43 Ų4333.6 Ų33.636%0.35519%0.192SC..Hα-helixtrans-60.3-41.7176.600000112.2M125 G126 L127 A132 L133 I149M125-A129 PolarHBondContact O-N 3.15Å; M125-A129 VanDerWaalsContact O-N 3.07Å; G126-A129 PolarHBondContact O-N 3.47Å; L127-A129 VanDerWaalsContact C-N 3.35Å; A129-A132 PolarHBondContact O-N 3.47Å; A129-L133 WeakPolarHBondContact O-CG 3.48Å; A129-L133 PolarHBondContact O-N 3.34Å; A129-I149 HydrophobicContact CB-CG2 4.47Å
130S97.7Very high95.7Very high2 Ų233.5 Ų33.51%0.01419%0.191CC..Hα-helixtrans-58.7-50.7174.61740000112.2G126 L127 I128 L133 W134 S146 G150G126-S130 WeakPolarHBondContact O-CB 3.44Å; G126-S130 PolarHBondContact O-N 3.02Å; L127-S130 WeakPolarHBondContact O-CB 3.36Å; L127-S130 PolarHBondContact O-N 3.38Å; I128-S130 VanDerWaalsContact C-N 3.32Å; I128-S130 PolarHBondContact O-N 3.08Å; S130-L133 PolarHBondContact O-N 2.96Å; S130-W134 PolarHBondContact O-N 2.91Å; S130-S146 WeakPolarHBondContact CB-O 3.37Å; S130-S146 WeakPolarHBondContact O-CB 3.47Å; S130-S146 PolarHBondContact OG-O 3.05Å; S130-G150 WeakPolarHBondContact OG-CA 3.46Å; S130-G150 PolarHBondContact OG-N 3.35Å
131Y97.8Very high95.4Very high4 Ų434.8 Ų34.82%0.01621%0.206CC..Hα-helixtrans-70.6-32.7-179.2-61.1-44.3000112.9F39 L127 I128 W134 A135 A216 A220F39-Y131 VanDerWaalsContact CA-OH 3.23Å; F39-Y131 WeakPolarHBondContact CA-OH 3.36Å; F39-Y131 PolarHBondContact N-OH 2.88Å; L127-Y131 HydrophobicContact CB-CE2 4.29Å; L127-Y131 VanDerWaalsContact O-CD2 3.22Å; L127-Y131 WeakPolarHBondContact O-CD2 3.12Å; L127-Y131 PolarHBondContact O-N 3.2Å; I128-Y131 PolarHBondContact O-N 3.35Å; Y131-W134 HydrophobicContact CD1-CE3 4.11Å; Y131-W134 PolarHBondContact O-N 2.89Å; Y131-A135 PolarHBondContact O-N 3.16Å; Y131-A216 HydrophobicContact CD1-CB 3.81Å; Y131-A216 HydrophobicContact CD2-CB 4.17Å; Y131-A216 WeakPolarHBondContact CD2-O 3.46Å; Y131-A216 HydrophobicContact CE1-CB 4.04Å; Y131-A216 HydrophobicContact CE2-CB 4.38Å; Y131-A216 HydrophobicContact CG-CB 3.89Å; Y131-A220 HydrophobicContact CD2-CB 3.61Å; Y131-A220 HydrophobicContact CE2-CB 3.81Å
132A98.1Very high95.2Very high41 Ų4136.3 Ų36.334%0.33921%0.214SC..Hα-helixtrans-62.6-44.7172.200000111.8I128 A129 W134 A135 A136 L217I128-A132 WeakPolarHBondContact O-CB 3.45Å; I128-A132 PolarHBondContact O-N 3.24Å; A129-A132 PolarHBondContact O-N 3.47Å; A132-W134 VanDerWaalsContact C-N 3.31Å; A132-W134 PolarHBondContact O-N 2.59Å; A132-A135 PolarHBondContact O-N 2.97Å; A132-A136 WeakPolarHBondContact O-CB 3.45Å; A132-A136 PolarHBondContact O-N 3.38Å; A132-L217 HydrophobicContact CB-CD1 4.28Å; A132-L217 HydrophobicContact CB-CD2 4.4Å
133L97.3Very high95Very high51 Ų5130.8 Ų30.827%0.26719%0.187SC..Hα-helixtrans-62.8-37.5173.8-75.1175000112.4A129 S130 A136 S137 I142 L145 I149A129-L133 WeakPolarHBondContact O-CG 3.48Å; A129-L133 PolarHBondContact O-N 3.34Å; S130-L133 PolarHBondContact O-N 2.96Å; L133-A136 CarbonylContact O-C 3.49Å; L133-A136 PolarHBondContact O-N 2.91Å; L133-S137 WeakPolarHBondContact O-CB 3.42Å; L133-S137 PolarHBondContact O-N 3.44Å; L133-I142 HydrophobicContact CD2-CG2 4.48Å; L133-L145 HydrophobicContact CD1-CD2 4.27Å; L133-L145 HydrophobicContact CD1-CG 4.18Å; L133-I149 HydrophobicContact CD1-CD1 3.49Å; L133-I149 VanDerWaalsContact CD1-CD1 3.49Å
134W96.6Very high94.7Very high0 Ų031.6 Ų31.60%019%0.191CC..Hα-helixtrans-66-43.2175.7-178.827000112I42 L45 I49 S130 Y131 A132 A136 S137 F143 F209 A213 A216I42-W134 HydrophobicContact CB-CH2 3.5Å; I42-W134 HydrophobicContact CB-CZ2 3.85Å; I42-W134 HydrophobicContact CB-CZ3 4.04Å; I42-W134 HydrophobicContact CD1-CD2 4.13Å; I42-W134 HydrophobicContact CD1-CH2 4.01Å; I42-W134 HydrophobicContact CD1-CZ2 3.52Å; I42-W134 HydrophobicContact CD1-CZ3 4.47Å; I42-W134 HydrophobicContact CG1-CH2 3.77Å; I42-W134 HydrophobicContact CG1-CZ2 3.53Å; L45-W134 HydrophobicContact CD1-CH2 4.47Å; L45-W134 HydrophobicContact CD1-CZ2 4.38Å; I49-W134 HydrophobicContact CD1-CZ2 4.18Å; S130-W134 PolarHBondContact O-N 2.91Å; Y131-W134 HydrophobicContact CD1-CE3 4.11Å; Y131-W134 PolarHBondContact O-N 2.89Å; A132-W134 VanDerWaalsContact C-N 3.31Å; A132-W134 PolarHBondContact O-N 2.59Å; W134-A136 PolarHBondContact O-N 3.25Å; W134-S137 PolarHBondContact O-N 2.72Å; W134-S137 VanDerWaalsContact O-N 3.12Å; W134-S137 PolarHBondContact O-OG 3.34Å; W134-F143 AromaticContact CD1-CD2 3.63Å; W134-F143 AromaticContact CD1-CE2 3.75Å; W134-F143 AromaticContact NE1-CD2 3.93Å; W134-F143 AromaticContact NE1-CE2 3.66Å; W134-F209 HydrophobicContact CZ2-CB 4.15Å; W134-F209 AromaticContact NE1-CD2 3.43Å; W134-F209 AromaticContact NE1-CE2 3.83Å; W134-A213 HydrophobicContact CB-CB 4.49Å; W134-A213 HydrophobicContact CD2-CB 3.55Å; W134-A213 HydrophobicContact CE3-CB 3.55Å; W134-A213 HydrophobicContact CG-CB 4Å; W134-A213 HydrophobicContact CH2-CB 4.25Å; W134-A213 HydrophobicContact CZ2-CB 4.25Å; W134-A213 VanDerWaalsContact CZ3-CA 3.5Å; W134-A213 HydrophobicContact CZ3-CB 3.93Å; W134-A216 HydrophobicContact CE3-CB 4.49Å; W134-A216 HydrophobicContact CZ3-CB 4.01Å
135A95.8Very high94.5Very high10 Ų1035.5 Ų35.58%0.08321%0.211CC..Hα-helixtrans-61.4-36.2174.700000111.9Y131 A132 R138 L210 A213 L214Y131-A135 PolarHBondContact O-N 3.16Å; A132-A135 PolarHBondContact O-N 2.97Å; A135-R138 PolarHBondContact O-NH1 2.88Å; A135-L210 HydrophobicContact CB-CD1 4.19Å; A135-L210 WeakPolarHBondContact O-CD1 3.35Å; A135-A213 HydrophobicContact CB-CB 3.93Å; A135-L214 HydrophobicContact CB-CD2 4.01Å
136A94.8Very high94.4Very high58 Ų5830.6 Ų30.648%0.47919%0.187SC..Hα-helixtrans-81.6-6.8176.900000114.3A132 L133 W134 R138A132-A136 WeakPolarHBondContact O-CB 3.45Å; A132-A136 PolarHBondContact O-N 3.38Å; L133-A136 CarbonylContact O-C 3.49Å; L133-A136 PolarHBondContact O-N 2.91Å; W134-A136 PolarHBondContact O-N 3.25Å; A136-R138 PolarHBondContact O-N 2.99Å
137S91.9Very high94.2Very high0 Ų030.6 Ų30.60%018%0.182CC..  trans-69.9121-170.566.50000111.4Y53 L133 W134Y53-S137 PolarHBondContact OH-OG 3.18Å; L133-S137 WeakPolarHBondContact O-CB 3.42Å; L133-S137 PolarHBondContact O-N 3.44Å; W134-S137 PolarHBondContact O-N 2.72Å; W134-S137 VanDerWaalsContact O-N 3.12Å; W134-S137 PolarHBondContact O-OG 3.34Å
138R88.9Confident94.1Very high125 Ų12533.2 Ų33.247%0.47220%0.196SC..  trans-115.1-18172.2-59.7-61.2178.3-92.6-1.1113A135 A136A135-R138 PolarHBondContact O-NH1 2.88Å; A136-R138 PolarHBondContact O-N 2.99Å
139T90.1Very high94Very high65 Ų6534.1 Ų34.140%0.39920%0.201SC..SBendtrans-117.3158.1173.6610000110.4G141 I142 F143T139-G141 VanDerWaalsContact C-N 3.26Å; T139-G141 PolarHBondContact O-N 3.24Å; T139-I142 PolarHBondContact O-N 2.87Å; T139-I142 WeakPolarHBondContact OG1-CG1 3.45Å; T139-F143 PolarHBondContact O-N 3.21Å
140F89.1Confident93.8Very high0 Ų032.2 Ų32.20%019%0.185CC..Hα-helixtrans-67.2-31179.9-179.9-106.8000111.5L50 Y53 D58 F60 Y61 L64 F88 F143 L144L50-F140 HydrophobicContact CD2-CE2 3.9Å; Y53-F140 HydrophobicContact CD1-CB 3.94Å; Y53-F140 HydrophobicContact CD2-CB 4.27Å; Y53-F140 AromaticContact CD2-CD2 3.74Å; Y53-F140 HydrophobicContact CD2-CD2 3.74Å; Y53-F140 HydrophobicContact CD2-CG 4.49Å; Y53-F140 HydrophobicContact CE1-CB 4.49Å; Y53-F140 HydrophobicContact CE2-CD2 4.39Å; Y53-F140 HydrophobicContact CG-CB 3.84Å; Y53-F140 HydrophobicContact CG-CD2 4.01Å; Y53-F140 HydrophobicContact CG-CG 4.38Å; D58-F140 HydrophobicContact CB-CB 4.38Å; D58-F140 WeakPolarHBondContact OD2-CB 3.39Å; D58-F140 PolarHBondContact OD2-N 3.09Å; F60-F140 AromaticContact CD1-CD1 3.73Å; F60-F140 HydrophobicContact CD1-CD1 3.73Å; F60-F140 AromaticContact CD1-CE1 3.84Å; F60-F140 HydrophobicContact CD1-CE1 3.84Å; F60-F140 HydrophobicContact CE1-CD1 4.38Å; F60-F140 HydrophobicContact CE1-CE1 4.12Å; Y61-F140 HydrophobicContact CD2-CD1 4.41Å; Y61-F140 HydrophobicContact CD2-CD2 4.13Å; Y61-F140 HydrophobicContact CD2-CE1 4.43Å; Y61-F140 HydrophobicContact CD2-CE2 4.13Å; Y61-F140 HydrophobicContact CD2-CG 4.28Å; Y61-F140 HydrophobicContact CD2-CZ 4.29Å; L64-F140 HydrophobicContact CD1-CE1 3.66Å; L64-F140 HydrophobicContact CD1-CZ 3.85Å; F88-F140 HydrophobicContact CZ-CZ 4.49Å; F140-F143 AromaticContact CD2-CD1 3.99Å; F140-F143 HydrophobicContact CD2-CD1 3.99Å; F140-F143 AromaticContact CE2-CD1 3.92Å; F140-F143 HydrophobicContact CE2-CD1 3.92Å; F140-F143 HydrophobicContact CE2-CE1 4.38Å; F140-F143 WeakPolarHBondContact O-CB 3.38Å; F140-F143 PolarHBondContact O-N 2.99Å; F140-L144 PolarHBondContact O-N 2.97Å
141G90.3Very high93.6Very high32 Ų3232.1 Ų32.133%0.3318%0.184SC..Hα-helixtrans-59.5-46.2174.100000113.8T139 F143 L144 L145T139-G141 VanDerWaalsContact C-N 3.26Å; T139-G141 PolarHBondContact O-N 3.24Å; G141-F143 VanDerWaalsContact C-N 3.31Å; G141-F143 PolarHBondContact O-N 3.42Å; G141-L144 PolarHBondContact O-N 3.27Å; G141-L145 WeakPolarHBondContact O-CB 3.25Å; G141-L145 PolarHBondContact O-N 3.5Å
142I92.7Very high93.4Very high62 Ų6236.2 Ų36.232%0.31821%0.206SC..Hα-helixtrans-66-39.3176.5-63170.3000110.2L133 T139 L145 S146L133-I142 HydrophobicContact CD2-CG2 4.48Å; T139-I142 PolarHBondContact O-N 2.87Å; T139-I142 WeakPolarHBondContact OG1-CG1 3.45Å; I142-L145 PolarHBondContact O-N 3.42Å; I142-S146 PolarHBondContact O-N 3.34Å
143F91.9Very high93.3Very high1 Ų135.1 Ų35.10%0.00420%0.195CC..Hα-helixtrans-58.7-48.3174.3174.9-103.9000111.7I42 F46 I49 Y53 W134 T139 F140 G141 S146 R147I42-F143 HydrophobicContact CD1-CE2 3.58Å; I42-F143 HydrophobicContact CD1-CZ 3.75Å; F46-F143 HydrophobicContact CD1-CZ 4.13Å; F46-F143 HydrophobicContact CE1-CE1 4.27Å; F46-F143 AromaticContact CE1-CZ 3.73Å; F46-F143 HydrophobicContact CE1-CZ 3.73Å; I49-F143 HydrophobicContact CD1-CE2 4.13Å; I49-F143 HydrophobicContact CD1-CZ 4.34Å; I49-F143 HydrophobicContact CG2-CD1 4.36Å; I49-F143 HydrophobicContact CG2-CD2 4.26Å; I49-F143 HydrophobicContact CG2-CE1 4.03Å; I49-F143 HydrophobicContact CG2-CE2 3.94Å; I49-F143 HydrophobicContact CG2-CG 4.45Å; I49-F143 HydrophobicContact CG2-CZ 3.8Å; Y53-F143 HydrophobicContact CE2-CB 3.84Å; Y53-F143 HydrophobicContact CE2-CD1 4.32Å; Y53-F143 HydrophobicContact CE2-CD2 4.42Å; Y53-F143 AromaticContact CE2-CG 3.93Å; Y53-F143 HydrophobicContact CE2-CG 3.93Å; W134-F143 AromaticContact CD1-CD2 3.63Å; W134-F143 AromaticContact CD1-CE2 3.75Å; W134-F143 AromaticContact NE1-CD2 3.93Å; W134-F143 AromaticContact NE1-CE2 3.66Å; T139-F143 PolarHBondContact O-N 3.21Å; F140-F143 AromaticContact CD2-CD1 3.99Å; F140-F143 HydrophobicContact CD2-CD1 3.99Å; F140-F143 AromaticContact CE2-CD1 3.92Å; F140-F143 HydrophobicContact CE2-CD1 3.92Å; F140-F143 HydrophobicContact CE2-CE1 4.38Å; F140-F143 WeakPolarHBondContact O-CB 3.38Å; F140-F143 PolarHBondContact O-N 2.99Å; G141-F143 VanDerWaalsContact C-N 3.31Å; G141-F143 PolarHBondContact O-N 3.42Å; F143-S146 VanDerWaalsContact O-CB 3.3Å; F143-S146 WeakPolarHBondContact O-CB 3.44Å; F143-S146 PolarHBondContact O-N 2.99Å; F143-S146 PolarHBondContact O-OG 3.27Å; F143-R147 HydrophobicContact CE1-CG 4.36Å; F143-R147 HydrophobicContact CZ-CG 4.34Å; F143-R147 PolarHBondContact O-N 2.86Å
144L90.4Very high92.9Very high23 Ų2333 Ų3312%0.1218%0.184CC..Hα-helixtrans-65.5-41.5177.9-17170.2000111.5F60 F140 G141 S146 R147 I148F60-L144 HydrophobicContact CE1-CB 4.28Å; F60-L144 HydrophobicContact CE1-CD2 3.31Å; F60-L144 HydrophobicContact CE1-CG 4.38Å; F60-L144 HydrophobicContact CZ-CD2 3.57Å; F140-L144 PolarHBondContact O-N 2.97Å; G141-L144 PolarHBondContact O-N 3.27Å; L144-S146 PolarHBondContact O-N 3.5Å; L144-R147 WeakPolarHBondContact O-CA 3.46Å; L144-R147 WeakPolarHBondContact O-CB 3.42Å; L144-R147 PolarHBondContact O-N 3.03Å; L144-I148 HydrophobicContact CD2-CD1 4.33Å; L144-I148 HydrophobicContact CG-CD1 4.19Å; L144-I148 HydrophobicContact CG-CG1 4.43Å; L144-I148 WeakPolarHBondContact O-CG1 3.19Å; L144-I148 PolarHBondContact O-N 2.91Å
145L93.3Very high92.6Very high81 Ų8133 Ų3342%0.42418%0.184SC..Hα-helixtrans-55.9-41175.2-178.761.9000111.2L133 G141 I142 R147 I148 I149L133-L145 HydrophobicContact CD1-CD2 4.27Å; L133-L145 HydrophobicContact CD1-CG 4.18Å; G141-L145 WeakPolarHBondContact O-CB 3.25Å; G141-L145 PolarHBondContact O-N 3.5Å; I142-L145 PolarHBondContact O-N 3.42Å; L145-R147 VanDerWaalsContact C-N 3.29Å; L145-R147 PolarHBondContact O-N 3.03Å; L145-I148 PolarHBondContact O-N 3.39Å; L145-I149 HydrophobicContact CD1-CD1 4.4Å; L145-I149 HydrophobicContact CD1-CG1 4.36Å; L145-I149 HydrophobicContact CG-CD1 4.34Å; L145-I149 WeakPolarHBondContact O-CG1 3.35Å; L145-I149 PolarHBondContact O-N 3.45Å
146S95.3Very high92.4Very high0 Ų032.7 Ų32.70%018%0.181CC..Hα-helixtrans-56-43.8173.2890000111.7S130 I142 F143 L144 G150S130-S146 WeakPolarHBondContact CB-O 3.37Å; S130-S146 WeakPolarHBondContact O-CB 3.47Å; S130-S146 PolarHBondContact OG-O 3.05Å; I142-S146 PolarHBondContact O-N 3.34Å; F143-S146 VanDerWaalsContact O-CB 3.3Å; F143-S146 WeakPolarHBondContact O-CB 3.44Å; F143-S146 PolarHBondContact O-N 2.99Å; F143-S146 PolarHBondContact O-OG 3.27Å; L144-S146 PolarHBondContact O-N 3.5Å; S146-G150 PolarHBondContact O-N 2.92Å
147R93.4Very high92.3Very high13 Ų1330.1 Ų30.15%0.04916%0.159CC..Hα-helixtrans-68.3-36.5179.1-60.4-5688.3169.19111.8F143 L144 L145 G150 G151F143-R147 HydrophobicContact CE1-CG 4.36Å; F143-R147 HydrophobicContact CZ-CG 4.34Å; F143-R147 PolarHBondContact O-N 2.86Å; L144-R147 WeakPolarHBondContact O-CA 3.46Å; L144-R147 WeakPolarHBondContact O-CB 3.42Å; L144-R147 PolarHBondContact O-N 3.03Å; L145-R147 VanDerWaalsContact C-N 3.29Å; L145-R147 PolarHBondContact O-N 3.03Å; R147-G150 PolarHBondContact O-N 2.89Å; R147-G151 PolarHBondContact O-N 3.45Å
148I93.9Very high92.3Very high58 Ų5830.1 Ų30.130%0.29716%0.159SC..Hα-helixtrans-63.7-52178.1-67.2169.2000110.6L99 L144 L145 G150 G151 I152L99-I148 HydrophobicContact CD1-CB 4.26Å; L99-I148 HydrophobicContact CD1-CG1 4.19Å; L99-I148 HydrophobicContact CD1-CG2 4.36Å; L99-I148 HydrophobicContact CD2-CG2 4.4Å; L144-I148 HydrophobicContact CD2-CD1 4.33Å; L144-I148 HydrophobicContact CG-CD1 4.19Å; L144-I148 HydrophobicContact CG-CG1 4.43Å; L144-I148 WeakPolarHBondContact O-CG1 3.19Å; L144-I148 PolarHBondContact O-N 2.91Å; L145-I148 PolarHBondContact O-N 3.39Å; I148-G150 VanDerWaalsContact C-N 3.32Å; I148-G150 PolarHBondContact O-N 2.9Å; I148-G151 PolarHBondContact O-N 2.81Å; I148-I152 HydrophobicContact CG2-CD1 3.85Å; I148-I152 WeakPolarHBondContact O-CG1 3.35Å; I148-I152 PolarHBondContact O-N 3.43Å
149I96.1Very high92.7Very high48 Ų4824.1 Ų24.125%0.24614%0.137CC..Hα-helixtrans-59.6-46.9177.4-63.2-176.3000109.9G126 A129 L133 L145 G151 I152 S153G126-I149 WeakPolarHBondContact O-CG2 3.47Å; A129-I149 HydrophobicContact CB-CG2 4.47Å; L133-I149 HydrophobicContact CD1-CD1 3.49Å; L133-I149 VanDerWaalsContact CD1-CD1 3.49Å; L145-I149 HydrophobicContact CD1-CD1 4.4Å; L145-I149 HydrophobicContact CD1-CG1 4.36Å; L145-I149 HydrophobicContact CG-CD1 4.34Å; L145-I149 WeakPolarHBondContact O-CG1 3.35Å; L145-I149 PolarHBondContact O-N 3.45Å; I149-G151 VanDerWaalsContact C-N 3.3Å; I149-G151 PolarHBondContact O-N 2.66Å; I149-I152 PolarHBondContact O-N 3.41Å; I149-S153 VanDerWaalsContact O-CB 3.26Å; I149-S153 WeakPolarHBondContact O-CB 3.28Å; I149-S153 PolarHBondContact O-N 2.87Å; I149-S153 PolarHBondContact O-OG 3.47Å
150G94.8Very high93Very high3 Ų321.2 Ų21.23%0.03112%0.119CC..Hα-helixtrans-59.8-37.8178.200000113.4S130 S146 R147 I148 S153 K154S130-G150 WeakPolarHBondContact OG-CA 3.46Å; S130-G150 PolarHBondContact OG-N 3.35Å; S146-G150 PolarHBondContact O-N 2.92Å; R147-G150 PolarHBondContact O-N 2.89Å; I148-G150 VanDerWaalsContact C-N 3.32Å; I148-G150 PolarHBondContact O-N 2.9Å; G150-S153 CarbonylContact O-C 3.58Å; G150-S153 PolarHBondContact O-N 3.4Å; G150-K154 WeakPolarHBondContact O-CB 3.41Å; G150-K154 PolarHBondContact O-N 2.9Å
151G93.1Very high93.3Very high0 Ų021.8 Ų21.80%012%0.122CC..Hα-helixtrans-70.3-43.5179.700000112.8F96 S103 R147 I148 I149 S153 K154F96-G151 VanDerWaalsContact CE2-N 3.27Å; S103-G151 PolarHBondContact OG-O 3.15Å; R147-G151 PolarHBondContact O-N 3.45Å; I148-G151 PolarHBondContact O-N 2.81Å; I149-G151 VanDerWaalsContact C-N 3.3Å; I149-G151 PolarHBondContact O-N 2.66Å; G151-S153 VanDerWaalsContact C-N 3.29Å; G151-S153 PolarHBondContact O-N 3.15Å; G151-K154 PolarHBondContact O-N 3.11Å
152I94.2Very high93.6Very high90 Ų9020.3 Ų20.346%0.46211%0.107SC..Hα-helixtrans-64.8-38.8175.1-63.8167.1000110.1L99 S103 I148 I149 K154L99-I152 HydrophobicContact CD2-CG1 4.2Å; S103-I152 VanDerWaalsContact CB-O 3.26Å; S103-I152 WeakPolarHBondContact CB-O 3.37Å; S103-I152 PolarHBondContact OG-O 3.31Å; I148-I152 HydrophobicContact CG2-CD1 3.85Å; I148-I152 WeakPolarHBondContact O-CG1 3.35Å; I148-I152 PolarHBondContact O-N 3.43Å; I149-I152 PolarHBondContact O-N 3.41Å; I152-K154 VanDerWaalsContact C-N 3.3Å; I152-K154 PolarHBondContact O-N 3.24Å
153S95.1Very high93.8Very high17 Ų1717.3 Ų17.312%0.1199%0.092CC..THydrogen-bonded Turntrans-80.3-1.9179.4-600000114.6T123 G126 I149 G150 G151 G155T123-S153 VanDerWaalsContact CB-O 3.27Å; T123-S153 WeakPolarHBondContact CB-O 3.48Å; T123-S153 WeakPolarHBondContact O-CB 3.23Å; G126-S153 WeakPolarHBondContact CA-OG 3.41Å; I149-S153 VanDerWaalsContact O-CB 3.26Å; I149-S153 WeakPolarHBondContact O-CB 3.28Å; I149-S153 PolarHBondContact O-N 2.87Å; I149-S153 PolarHBondContact O-OG 3.47Å; G150-S153 CarbonylContact O-C 3.58Å; G150-S153 PolarHBondContact O-N 3.4Å; G151-S153 VanDerWaalsContact C-N 3.29Å; G151-S153 PolarHBondContact O-N 3.15Å; S153-G155 PolarHBondContact O-N 2.95Å
154K90.3Very high94.1Very high7 Ų717.3 Ų17.33%0.039%0.092CC..THydrogen-bonded Turntrans-78.716.4179.2-143.665175168.70114.7D35 F96 Q100 L127 G150 G151 I152 N156 V157D35-K154 IonicContact OD1-NZ 2.96Å; D35-K154 PolarHBondContact OD1-NZ 2.89Å; D35-K154 WeakPolarHBondContact OD2-CE 3.24Å; D35-K154 IonicContact OD2-NZ 3.24Å; D35-K154 PolarHBondContact OD2-NZ 2.98Å; F96-K154 HydrophobicContact CE1-CG 4.38Å; F96-K154 HydrophobicContact CZ-CB 4.31Å; F96-K154 HydrophobicContact CZ-CD 4.34Å; F96-K154 HydrophobicContact CZ-CG 4.19Å; Q100-K154 HydrophobicContact CG-CB 4.02Å; L127-K154 HydrophobicContact CD1-CD 4.48Å; L127-K154 HydrophobicContact CD2-CD 3.87Å; G150-K154 WeakPolarHBondContact O-CB 3.41Å; G150-K154 PolarHBondContact O-N 2.9Å; G151-K154 PolarHBondContact O-N 3.11Å; I152-K154 VanDerWaalsContact C-N 3.3Å; I152-K154 PolarHBondContact O-N 3.24Å; K154-N156 PolarHBondContact O-N 3.41Å; K154-N156 PolarHBondContact O-OD1 3.48Å; K154-V157 HydrophobicContact CG-CG2 4.42Å
155G88.4Confident94.3Very high0 Ų016.3 Ų16.30%09%0.087CC..THydrogen-bonded Turntrans-64.3-1717200000113.6S153 V157 S158 L159S153-G155 PolarHBondContact O-N 2.95Å; G155-V157 PolarHBondContact O-N 2.96Å; G155-S158 WeakPolarHBondContact O-CB 3.38Å; G155-S158 PolarHBondContact O-N 3.19Å; G155-L159 WeakPolarHBondContact O-CG 3.4Å; G155-L159 PolarHBondContact O-N 3.19Å
156N92.1Very high94.4Very high3 Ų313.6 Ų13.62%0.0167%0.073CC..Hα-helixtrans-54.6-34176.670.8-41.7000113.6D35 I120 T123 K154 L159 S160D35-N156 PolarHBondContact OD2-ND2 2.88Å; I120-N156 HydrophobicContact CG1-CB 4.15Å; T123-N156 WeakPolarHBondContact OG1-CB 3.47Å; K154-N156 PolarHBondContact O-N 3.41Å; K154-N156 PolarHBondContact O-OD1 3.48Å; N156-L159 PolarHBondContact O-N 3.1Å; N156-S160 WeakPolarHBondContact O-CB 3.49Å; N156-S160 PolarHBondContact O-N 3.35Å; N156-S160 PolarHBondContact O-OG 2.7Å
157V92.3Very high94.2Very high4 Ų414.5 Ų14.52%0.0248%0.077CC..Hα-helixtrans-64.7-47.8174.8176.60000111.1L32 K154 G155 L159 S160 T161 F184L32-V157 HydrophobicContact CD1-CG2 4.1Å; K154-V157 HydrophobicContact CG-CG2 4.42Å; G155-V157 PolarHBondContact O-N 2.96Å; V157-L159 VanDerWaalsContact C-N 3.33Å; V157-S160 WeakPolarHBondContact O-CB 3.2Å; V157-S160 PolarHBondContact O-N 3.39Å; V157-T161 PolarHBondContact O-N 2.79Å; V157-T161 VanDerWaalsContact O-N 3.15Å; V157-F184 HydrophobicContact CB-CZ 4.44Å; V157-F184 HydrophobicContact CG1-CE2 3.88Å; V157-F184 HydrophobicContact CG1-CZ 3.55Å; V157-F184 HydrophobicContact CG2-CZ 3.98Å
158S93.4Very high93.9Very high0 Ų020.6 Ų20.60%011%0.106CC..Hα-helixtrans-60.4-45.6176.7173.60000110.6G155 S160 T161 A162 G407G155-S158 WeakPolarHBondContact O-CB 3.38Å; G155-S158 PolarHBondContact O-N 3.19Å; S158-S160 VanDerWaalsContact C-N 3.34Å; S158-S160 PolarHBondContact O-N 2.78Å; S158-T161 PolarHBondContact O-N 2.8Å; S158-T161 VanDerWaalsContact O-N 3.15Å; S158-T161 PolarHBondContact O-OG1 3.49Å; S158-A162 PolarHBondContact O-N 2.96Å; S158-G407 VanDerWaalsContact OG-CA 3.24Å; S158-G407 WeakPolarHBondContact OG-CA 3.44Å; S158-G407 PolarHBondContact OG-N 3.46Å
159L96Very high93.6Very high0 Ų020.4 Ų20.40%011%0.11CC..Hα-helixtrans-62.7-38.9177.4-65.1176.2000112.7T107 S111 V119 I120 T123 G155 N156 V157 T161 A162 I163T107-L159 HydrophobicContact CG2-CD1 3.67Å; T107-L159 HydrophobicContact CG2-CD2 4.09Å; T107-L159 HydrophobicContact CG2-CG 3.88Å; S111-L159 WeakPolarHBondContact OG-CD2 3.44Å; V119-L159 HydrophobicContact CB-CD1 4.09Å; V119-L159 HydrophobicContact CG1-CD1 3.83Å; V119-L159 HydrophobicContact CG1-CD2 4.41Å; I120-L159 VanDerWaalsContact CA-CD1 3.49Å; I120-L159 HydrophobicContact CB-CB 4.43Å; I120-L159 HydrophobicContact CB-CD1 3.78Å; I120-L159 HydrophobicContact CD1-CB 4.45Å; I120-L159 HydrophobicContact CG1-CB 4.49Å; I120-L159 HydrophobicContact CG1-CD1 4.29Å; T123-L159 HydrophobicContact CG2-CD1 4.27Å; G155-L159 WeakPolarHBondContact O-CG 3.4Å; G155-L159 PolarHBondContact O-N 3.19Å; N156-L159 PolarHBondContact O-N 3.1Å; V157-L159 VanDerWaalsContact C-N 3.33Å; L159-T161 VanDerWaalsContact C-N 3.31Å; L159-T161 PolarHBondContact O-N 2.67Å; L159-A162 CarbonylContact O-C 3.59Å; L159-A162 WeakPolarHBondContact O-CB 3.41Å; L159-A162 PolarHBondContact O-N 3.27Å; L159-A162 VanDerWaalsContact O-N 3.11Å; L159-I163 WeakPolarHBondContact O-CD1 3.29Å; L159-I163 VanDerWaalsContact O-CG1 3.23Å; L159-I163 WeakPolarHBondContact O-CG1 3.27Å; L159-I163 PolarHBondContact O-N 3.14Å
160S96.9Very high93.4Very high3 Ų321.1 Ų21.12%0.02112%0.118CC..Hα-helixtrans-58.8-44.6174.2-640000111N156 V157 S158 A162 I163 I164N156-S160 WeakPolarHBondContact O-CB 3.49Å; N156-S160 PolarHBondContact O-N 3.35Å; N156-S160 PolarHBondContact O-OG 2.7Å; V157-S160 WeakPolarHBondContact O-CB 3.2Å; V157-S160 PolarHBondContact O-N 3.39Å; S158-S160 VanDerWaalsContact C-N 3.34Å; S158-S160 PolarHBondContact O-N 2.78Å; S160-A162 VanDerWaalsContact C-N 3.35Å; S160-A162 PolarHBondContact O-N 2.77Å; S160-I163 PolarHBondContact O-N 2.92Å; S160-I164 WeakPolarHBondContact O-CG1 3.32Å; S160-I164 PolarHBondContact O-N 3.48Å; S160-I164 VanDerWaalsContact O-N 3.1Å
161T96.5Very high93.2Very high13 Ų1326.6 Ų26.68%0.0814%0.141CC..Hα-helixtrans-67.1-34174.761.20000112.8V157 S158 L159 I164 A165 M177 I180 M406V157-T161 PolarHBondContact O-N 2.79Å; V157-T161 VanDerWaalsContact O-N 3.15Å; S158-T161 PolarHBondContact O-N 2.8Å; S158-T161 VanDerWaalsContact O-N 3.15Å; S158-T161 PolarHBondContact O-OG1 3.49Å; L159-T161 VanDerWaalsContact C-N 3.31Å; L159-T161 PolarHBondContact O-N 2.67Å; T161-I164 PolarHBondContact O-N 3.47Å; T161-A165 WeakPolarHBondContact O-CB 3.29Å; T161-A165 PolarHBondContact O-N 2.91Å; T161-M177 HydrophobicContact CG2-SD 4.09Å; T161-M177 WeakPolarHBondContact O-CE 3.31Å; T161-I180 HydrophobicContact CG2-CD1 3.75Å; T161-I180 HydrophobicContact CG2-CG2 4.43Å; T161-M406 HydrophobicContact CG2-CE 4.44Å
162A96.1Very high93.2Very high0 Ų027.4 Ų27.40%015%0.147CC..Hα-helixtrans-67.9-41.3174.500000112.5S158 L159 S160 I164 A165 D166 M406S158-A162 PolarHBondContact O-N 2.96Å; L159-A162 CarbonylContact O-C 3.59Å; L159-A162 WeakPolarHBondContact O-CB 3.41Å; L159-A162 PolarHBondContact O-N 3.27Å; L159-A162 VanDerWaalsContact O-N 3.11Å; S160-A162 VanDerWaalsContact C-N 3.35Å; S160-A162 PolarHBondContact O-N 2.77Å; A162-I164 VanDerWaalsContact C-N 3.31Å; A162-I164 PolarHBondContact O-N 3.44Å; A162-A165 CarbonylContact O-C 3.24Å; A162-A165 WeakPolarHBondContact O-CA 3.46Å; A162-A165 WeakPolarHBondContact O-CB 3.32Å; A162-A165 PolarHBondContact O-N 3.23Å; A162-D166 VanDerWaalsContact O-CG 3.3Å; A162-D166 PolarHBondContact O-N 3.49Å; A162-M406 HydrophobicContact CB-CB 4.41Å
163I97.1Very high93.2Very high0 Ų025 Ų250%013%0.132CC..Hα-helixtrans-60.2-42.8174.8-70.1160.9000110.4V24 V28 R116 I120 L159 S160 A165 D166 L231 T234V24-I163 HydrophobicContact CG1-CG2 3.65Å; V28-I163 HydrophobicContact CG2-CB 4.26Å; V28-I163 HydrophobicContact CG2-CG2 3.58Å; R116-I163 HydrophobicContact CB-CD1 4.15Å; R116-I163 HydrophobicContact CB-CG1 3.64Å; R116-I163 HydrophobicContact CG-CG1 3.86Å; I120-I163 HydrophobicContact CD1-CD1 4.11Å; L159-I163 WeakPolarHBondContact O-CD1 3.29Å; L159-I163 VanDerWaalsContact O-CG1 3.23Å; L159-I163 WeakPolarHBondContact O-CG1 3.27Å; L159-I163 PolarHBondContact O-N 3.14Å; S160-I163 PolarHBondContact O-N 2.92Å; I163-A165 VanDerWaalsContact C-N 3.33Å; I163-D166 PolarHBondContact O-N 2.98Å; I163-L231 HydrophobicContact CD1-CD1 4.4Å; I163-L231 HydrophobicContact CD1-CD2 3.92Å; I163-T234 HydrophobicContact CG2-CG2 3.81Å
164I97.1Very high93.1Very high1 Ų124.8 Ų24.81%0.00513%0.131CC..Hα-helixtrans-65.5-38.4173.1-64.3-51.8000111I25 V28 S160 T161 A162 D166 L167 R173 M177 I180I25-I164 HydrophobicContact CB-CD1 4.44Å; I25-I164 HydrophobicContact CG1-CD1 3.88Å; V28-I164 HydrophobicContact CB-CD1 4.18Å; V28-I164 HydrophobicContact CG1-CD1 4.25Å; V28-I164 HydrophobicContact CG1-CG1 4.22Å; V28-I164 HydrophobicContact CG2-CD1 4.26Å; S160-I164 WeakPolarHBondContact O-CG1 3.32Å; S160-I164 PolarHBondContact O-N 3.48Å; S160-I164 VanDerWaalsContact O-N 3.1Å; T161-I164 PolarHBondContact O-N 3.47Å; A162-I164 VanDerWaalsContact C-N 3.31Å; A162-I164 PolarHBondContact O-N 3.44Å; I164-D166 VanDerWaalsContact C-N 3.26Å; I164-D166 PolarHBondContact O-N 3.2Å; I164-L167 HydrophobicContact CD1-CD1 4.19Å; I164-L167 HydrophobicContact CG2-CD1 4.44Å; I164-L167 VanDerWaalsContact O-CB 3.28Å; I164-L167 WeakPolarHBondContact O-CB 3.46Å; I164-L167 VanDerWaalsContact O-CG 3.29Å; I164-L167 WeakPolarHBondContact O-CG 3.44Å; I164-L167 PolarHBondContact O-N 3.4Å; I164-L167 VanDerWaalsContact O-N 3.14Å; I164-R173 WeakPolarHBondContact O-CG 3.32Å; I164-M177 HydrophobicContact CB-CE 4.24Å; I164-M177 HydrophobicContact CG2-CE 4.03Å; I164-M177 HydrophobicContact CG2-CG 4.2Å; I164-M177 HydrophobicContact CG2-SD 4.21Å; I164-I180 HydrophobicContact CB-CD1 4.44Å; I164-I180 HydrophobicContact CG1-CD1 3.72Å; I164-I180 HydrophobicContact CG1-CG1 4.45Å
165A95.4Very high93.3Very high2 Ų226.6 Ų26.62%0.01714%0.139CC..Hα-helixtrans-66.9-23.8177.900000113.9T161 A162 I163 L167 K402 M406T161-A165 WeakPolarHBondContact O-CB 3.29Å; T161-A165 PolarHBondContact O-N 2.91Å; A162-A165 CarbonylContact O-C 3.24Å; A162-A165 WeakPolarHBondContact O-CA 3.46Å; A162-A165 WeakPolarHBondContact O-CB 3.32Å; A162-A165 PolarHBondContact O-N 3.23Å; I163-A165 VanDerWaalsContact C-N 3.33Å; A165-L167 PolarHBondContact O-N 3.47Å; A165-K402 HydrophobicContact CB-CB 4.11Å; A165-K402 HydrophobicContact CB-CD 4.13Å; A165-K402 HydrophobicContact CB-CG 4.26Å; A165-M406 HydrophobicContact CB-CG 4.07Å
166D94.4Very high93.7Very high24 Ų2426.6 Ų26.613%0.12814%0.139CC..THydrogen-bonded Turntrans-71.3-13.4173.6-65.5-25.7000112.3R116 A162 I163 I164 T234R116-D166 WeakPolarHBondContact CG-OD2 3.22Å; R116-D166 IonicContact CZ-OD1 3.64Å; R116-D166 IonicContact CZ-OD2 3.49Å; R116-D166 IonicContact NE-OD1 3.98Å; R116-D166 IonicContact NE-OD2 3.97Å; R116-D166 PolarHBondContact NE-OD2 3.3Å; R116-D166 IonicContact NH2-OD1 2.66Å; R116-D166 PolarHBondContact NH2-OD1 3.49Å; R116-D166 IonicContact NH2-OD2 2.64Å; A162-D166 VanDerWaalsContact O-CG 3.3Å; A162-D166 PolarHBondContact O-N 3.49Å; I163-D166 PolarHBondContact O-N 2.98Å; I164-D166 VanDerWaalsContact C-N 3.26Å; I164-D166 PolarHBondContact O-N 3.2Å; D166-T234 PolarHBondContact OD2-OG1 3Å
167L92.8Very high93.9Very high19 Ų1926.6 Ų26.610%0.09914%0.139CC..  trans-69.3132177-59.4178.2000111.7V24 I25 I164 A165 S169 A172 R173V24-L167 HydrophobicContact CB-CD2 4.28Å; V24-L167 HydrophobicContact CG1-CD2 4.27Å; I25-L167 HydrophobicContact CD1-CD1 3.94Å; I25-L167 HydrophobicContact CG1-CD1 3.68Å; I164-L167 HydrophobicContact CD1-CD1 4.19Å; I164-L167 HydrophobicContact CG2-CD1 4.44Å; I164-L167 VanDerWaalsContact O-CB 3.28Å; I164-L167 WeakPolarHBondContact O-CB 3.46Å; I164-L167 VanDerWaalsContact O-CG 3.29Å; I164-L167 WeakPolarHBondContact O-CG 3.44Å; I164-L167 PolarHBondContact O-N 3.4Å; I164-L167 VanDerWaalsContact O-N 3.14Å; A165-L167 PolarHBondContact O-N 3.47Å; L167-S169 PolarHBondContact O-N 3.36Å; L167-A172 HydrophobicContact CB-CB 4.25Å; L167-A172 HydrophobicContact CD1-CB 4.1Å; L167-R173 HydrophobicContact CB-CG 4.18Å; L167-R173 WeakPolarHBondContact O-CD 3.41Å; L167-R173 WeakPolarHBondContact O-CG 3.42Å
168H85.2Confident94.2Very high140 Ų14026.4 Ų26.465%0.64814%0.138SC*.SBendtrans-62.6-42.1-173.9-59.392.9000114.1
169S89.6Confident94.4Very high55 Ų5527.6 Ų27.639%0.38514%0.144SC..  trans-83.8130-172.9177.50000112.1L167 K171 A172 R173L167-S169 PolarHBondContact O-N 3.36Å; S169-K171 PolarHBondContact O-N 2.94Å; S169-K171 PolarHBondContact OG-N 3.3Å; S169-A172 WeakPolarHBondContact O-CB 3.22Å; S169-A172 PolarHBondContact O-N 3.48Å; S169-R173 PolarHBondContact O-N 2.65Å
170P89.9Confident94.4Very high63 Ų6328.2 Ų28.241%0.40915%0.147SC..Hα-helixtrans-52.8-38.6170.1-2432.2000112.8A172 R173 S174 P341P170-A172 VanDerWaalsContact C-N 3.33Å; P170-A172 PolarHBondContact O-N 2.87Å; P170-R173 PolarHBondContact O-N 2.89Å; P170-S174 PolarHBondContact O-N 3.21Å; P170-S174 PolarHBondContact O-OG 2.99Å; P170-S174 VanDerWaalsContact O-OG 3.07Å; P170-P341 HydrophobicContact CB-CB 3.89Å; P170-P341 HydrophobicContact CB-CG 4.08Å
171K91.3Very high94.4Very high118 Ų11828.4 Ų28.451%0.51315%0.15SC..Hα-helixtrans-62.9-40.5177.5-176-172171.1-155.60111.5E18 S169 K175 P341E18-K171 IonicContact OE1-NZ 3Å; E18-K171 PolarHBondContact OE1-NZ 3.21Å; S169-K171 PolarHBondContact O-N 2.94Å; S169-K171 PolarHBondContact OG-N 3.3Å; K171-K175 VanDerWaalsContact O-CB 3.24Å; K171-K175 WeakPolarHBondContact O-CB 3.39Å; K171-K175 PolarHBondContact O-N 3.03Å; K171-P341 HydrophobicContact CB-CG 4.02Å
172A92.8Very high94.5Very high17 Ų1728.4 Ų28.414%0.1415%0.15CC..Hα-helixtrans-68.3-42.3177.300000111.7I25 L167 S169 P170 K175 G176I25-A172 HydrophobicContact CD1-CB 4.38Å; I25-A172 WeakPolarHBondContact CD1-O 3.43Å; L167-A172 HydrophobicContact CB-CB 4.25Å; L167-A172 HydrophobicContact CD1-CB 4.1Å; S169-A172 WeakPolarHBondContact O-CB 3.22Å; S169-A172 PolarHBondContact O-N 3.48Å; P170-A172 VanDerWaalsContact C-N 3.33Å; P170-A172 PolarHBondContact O-N 2.87Å; A172-K175 PolarHBondContact O-N 3.43Å; A172-G176 PolarHBondContact O-N 3.31Å
173R94.3Very high94.6Very high38 Ų3828.4 Ų28.414%0.14315%0.15CC..Hα-helixtrans-60.1-51175.1-67.9-174.1-70179.8-3111.7I164 L167 S169 P170 K175 G176 M177 S394I164-R173 WeakPolarHBondContact O-CG 3.32Å; L167-R173 HydrophobicContact CB-CG 4.18Å; L167-R173 WeakPolarHBondContact O-CD 3.41Å; L167-R173 WeakPolarHBondContact O-CG 3.42Å; S169-R173 PolarHBondContact O-N 2.65Å; P170-R173 PolarHBondContact O-N 2.89Å; R173-K175 PolarHBondContact O-N 3.46Å; R173-G176 PolarHBondContact O-N 3.17Å; R173-M177 VanDerWaalsContact O-CG 3.32Å; R173-M177 WeakPolarHBondContact O-CG 3.39Å; R173-M177 PolarHBondContact O-N 2.94Å; R173-S394 PolarHBondContact NH1-O 2.92Å
174S93.7Very high94.5Very high13 Ų1330.8 Ų30.89%0.09116%0.16CC..Hα-helixtrans-60.4-45178.3-580000112.1P170 A178 E344P170-S174 PolarHBondContact O-N 3.21Å; P170-S174 PolarHBondContact O-OG 2.99Å; P170-S174 VanDerWaalsContact O-OG 3.07Å; S174-A178 PolarHBondContact O-N 3.45Å; S174-A178 VanDerWaalsContact O-N 3.12Å; S174-E344 PolarHBondContact OG-OE1 3.37Å
175K95.1Very high94.5Very high45 Ų4531 Ų3120%0.19616%0.162CC..Hα-helixtrans-60.7-45.3173.3171.1175.9172.3-176.80112.1N22 I25 K171 A172 R173 A178 M179 R337N22-K175 PolarHBondContact OD1-NZ 2.89Å; I25-K175 HydrophobicContact CD1-CD 4.31Å; I25-K175 HydrophobicContact CD1-CG 4.24Å; K171-K175 VanDerWaalsContact O-CB 3.24Å; K171-K175 WeakPolarHBondContact O-CB 3.39Å; K171-K175 PolarHBondContact O-N 3.03Å; A172-K175 PolarHBondContact O-N 3.43Å; R173-K175 PolarHBondContact O-N 3.46Å; K175-A178 PolarHBondContact O-N 2.95Å; K175-M179 WeakPolarHBondContact O-CG 3.39Å; K175-M179 PolarHBondContact O-N 2.98Å; K175-R337 HydrophobicContact CB-CG 4.39Å; K175-R337 VanDerWaalsContact CE-CZ 3.48Å; K175-R337 HydrophobicContact CG-CG 3.94Å
176G96.3Very high94.6Very high0 Ų033 Ų330%017%0.172CC..Hα-helixtrans-63.3-44179.900000112.5A172 R173 A178 M179 I180A172-G176 PolarHBondContact O-N 3.31Å; R173-G176 PolarHBondContact O-N 3.17Å; G176-A178 VanDerWaalsContact C-N 3.32Å; G176-A178 PolarHBondContact O-N 3.06Å; G176-M179 PolarHBondContact O-N 2.91Å; G176-M179 VanDerWaalsContact O-N 3.16Å; G176-I180 PolarHBondContact O-N 3.44Å
177M96.8Very high94.7Very high3 Ų331.9 Ų31.92%0.01517%0.166CC..Hα-helixtrans-64-37.1176.5-66.6-59.6-179.700112.1T161 I164 R173 I180 G181 P387 A391 M406T161-M177 HydrophobicContact CG2-SD 4.09Å; T161-M177 WeakPolarHBondContact O-CE 3.31Å; I164-M177 HydrophobicContact CB-CE 4.24Å; I164-M177 HydrophobicContact CG2-CE 4.03Å; I164-M177 HydrophobicContact CG2-CG 4.2Å; I164-M177 HydrophobicContact CG2-SD 4.21Å; R173-M177 VanDerWaalsContact O-CG 3.32Å; R173-M177 WeakPolarHBondContact O-CG 3.39Å; R173-M177 PolarHBondContact O-N 2.94Å; M177-I180 PolarHBondContact O-N 3.29Å; M177-I180 HydrophobicContact SD-CD1 4.25Å; M177-G181 PolarHBondContact O-N 3.02Å; M177-G181 VanDerWaalsContact O-N 3.08Å; M177-P387 HydrophobicContact CB-CB 4.49Å; M177-P387 WeakPolarHBondContact CB-O 3.47Å; M177-A391 HydrophobicContact CB-CB 4.27Å; M177-A391 HydrophobicContact CG-CB 4.13Å; M177-M406 HydrophobicContact CE-CE 3.71Å; M177-M406 HydrophobicContact CE-SD 4.42Å; M177-M406 HydrophobicContact SD-CE 4.5Å
178A96.9Very high94.7Very high1 Ų134.8 Ų34.81%0.00818%0.178CC..Hα-helixtrans-64.8-41.7172.500000112.1S174 K175 G176 G181 V182 A336 R337 P387S174-A178 PolarHBondContact O-N 3.45Å; S174-A178 VanDerWaalsContact O-N 3.12Å; K175-A178 PolarHBondContact O-N 2.95Å; G176-A178 VanDerWaalsContact C-N 3.32Å; G176-A178 PolarHBondContact O-N 3.06Å; A178-G181 WeakPolarHBondContact O-CA 3.2Å; A178-G181 PolarHBondContact O-N 2.86Å; A178-G181 VanDerWaalsContact O-N 3.08Å; A178-V182 PolarHBondContact O-N 3.28Å; A178-A336 HydrophobicContact CB-CB 4.4Å; A178-R337 HydrophobicContact CB-CB 3.79Å; A178-P387 HydrophobicContact CB-CB 4.43Å
179M97.5Very high95.2Very high25 Ų2528.4 Ų28.412%0.12315%0.149CC..Hα-helixtrans-64.9-37.7175.8-69.4-57.5-55.800112.4I25 F29 K175 G176 G181 V182 A183 R337I25-M179 HydrophobicContact CG2-CB 4.04Å; I25-M179 HydrophobicContact CG2-CG 3.82Å; F29-M179 HydrophobicContact CB-CB 4.44Å; F29-M179 HydrophobicContact CB-CE 4.44Å; F29-M179 HydrophobicContact CD1-CE 4.15Å; F29-M179 HydrophobicContact CD2-CB 4.41Å; F29-M179 HydrophobicContact CD2-CE 3.7Å; F29-M179 WeakPolarHBondContact CD2-O 3.34Å; F29-M179 HydrophobicContact CE1-CE 4.37Å; F29-M179 HydrophobicContact CE2-CE 3.93Å; F29-M179 HydrophobicContact CG-CE 3.81Å; F29-M179 HydrophobicContact CZ-CE 4.26Å; K175-M179 WeakPolarHBondContact O-CG 3.39Å; K175-M179 PolarHBondContact O-N 2.98Å; G176-M179 PolarHBondContact O-N 2.91Å; G176-M179 VanDerWaalsContact O-N 3.16Å; M179-G181 VanDerWaalsContact C-N 3.27Å; M179-G181 PolarHBondContact O-N 2.81Å; M179-V182 WeakPolarHBondContact O-CB 3.46Å; M179-V182 PolarHBondContact O-N 3.15Å; M179-V182 VanDerWaalsContact O-N 3.12Å; M179-A183 PolarHBondContact O-N 2.99Å; M179-R337 PolarHBondContact SD-NH1 2.92Å; M179-R337 VanDerWaalsContact SD-NH1 3.41Å
180I97.3Very high95.4Very high12 Ų1229.1 Ų29.16%0.06215%0.148CC..Hα-helixtrans-56.4-45.3169.2-74.4176000110V28 L32 T161 I164 G176 M177 V182 A183 F184V28-I180 HydrophobicContact CG1-CD1 4.37Å; V28-I180 HydrophobicContact CG1-CG1 4.35Å; L32-I180 HydrophobicContact CD2-CB 4.21Å; L32-I180 HydrophobicContact CD2-CG1 4.08Å; L32-I180 HydrophobicContact CD2-CG2 3.72Å; T161-I180 HydrophobicContact CG2-CD1 3.75Å; T161-I180 HydrophobicContact CG2-CG2 4.43Å; I164-I180 HydrophobicContact CB-CD1 4.44Å; I164-I180 HydrophobicContact CG1-CD1 3.72Å; I164-I180 HydrophobicContact CG1-CG1 4.45Å; G176-I180 PolarHBondContact O-N 3.44Å; M177-I180 PolarHBondContact O-N 3.29Å; M177-I180 HydrophobicContact SD-CD1 4.25Å; I180-V182 VanDerWaalsContact C-N 3.33Å; I180-V182 PolarHBondContact O-N 3.05Å; I180-A183 WeakPolarHBondContact O-CB 3.41Å; I180-A183 PolarHBondContact O-N 2.89Å; I180-A183 VanDerWaalsContact O-N 3.16Å; I180-F184 HydrophobicContact CG2-CD2 3.98Å; I180-F184 HydrophobicContact CG2-CE2 3.99Å; I180-F184 WeakPolarHBondContact O-CD2 3.25Å; I180-F184 PolarHBondContact O-N 3.3Å; I180-F184 VanDerWaalsContact O-N 3.07Å
181G96.5Very high95.7Very high8 Ų826.1 Ų26.18%0.08213%0.128CC..Hα-helixtrans-53.9-47.5172.800000112.8M177 A178 M179 A183 F184 S185 Q332M177-G181 PolarHBondContact O-N 3.02Å; M177-G181 VanDerWaalsContact O-N 3.08Å; A178-G181 WeakPolarHBondContact O-CA 3.2Å; A178-G181 PolarHBondContact O-N 2.86Å; A178-G181 VanDerWaalsContact O-N 3.08Å; M179-G181 VanDerWaalsContact C-N 3.27Å; M179-G181 PolarHBondContact O-N 2.81Å; G181-A183 VanDerWaalsContact C-N 3.31Å; G181-A183 PolarHBondContact O-N 3.4Å; G181-F184 WeakPolarHBondContact O-CB 3.47Å; G181-F184 PolarHBondContact O-N 3.32Å; G181-F184 VanDerWaalsContact O-N 3.15Å; G181-S185 PolarHBondContact O-N 3.16Å; G181-S185 PolarHBondContact O-OG 3.3Å; G181-Q332 VanDerWaalsContact C-CD 3.42Å; G181-Q332 PolarHBondContact O-OE1 3.39Å
182V98.1Very high95.8Very high13 Ų1321.8 Ų21.88%0.07911%0.113CC..Hα-helixtrans-59.1-41.7177.5179.90000111.4F29 A178 M179 I180 F184 S185 L186 A329 Q332F29-V182 HydrophobicContact CE2-CB 4.11Å; F29-V182 HydrophobicContact CE2-CG1 3.9Å; F29-V182 HydrophobicContact CZ-CG1 4.42Å; A178-V182 PolarHBondContact O-N 3.28Å; M179-V182 WeakPolarHBondContact O-CB 3.46Å; M179-V182 PolarHBondContact O-N 3.15Å; M179-V182 VanDerWaalsContact O-N 3.12Å; I180-V182 VanDerWaalsContact C-N 3.33Å; I180-V182 PolarHBondContact O-N 3.05Å; V182-F184 VanDerWaalsContact C-N 3.34Å; V182-F184 PolarHBondContact O-N 2.83Å; V182-S185 PolarHBondContact O-N 2.9Å; V182-L186 HydrophobicContact CG1-CD1 3.82Å; V182-L186 HydrophobicContact CG1-CG 4.15Å; V182-L186 WeakPolarHBondContact O-CB 3.45Å; V182-L186 WeakPolarHBondContact O-CG 3.44Å; V182-L186 PolarHBondContact O-N 3.21Å; V182-A329 HydrophobicContact CG1-CB 4.47Å; V182-Q332 HydrophobicContact CG2-CB 3.58Å
183A97.9Very high95.8Very high0 Ų025.8 Ų25.80%013%0.129CC..Hα-helixtrans-61.4-42.2176.700000111.9F29 L32 L33 L36 M179 I180 G181 G187F29-A183 HydrophobicContact CD2-CB 3.81Å; F29-A183 HydrophobicContact CE2-CB 3.97Å; L32-A183 HydrophobicContact CB-CB 4.32Å; L32-A183 HydrophobicContact CD2-CB 4.17Å; L32-A183 HydrophobicContact CG-CB 4.29Å; L33-A183 HydrophobicContact CB-CB 4.22Å; L36-A183 HydrophobicContact CD1-CB 4.25Å; M179-A183 PolarHBondContact O-N 2.99Å; I180-A183 WeakPolarHBondContact O-CB 3.41Å; I180-A183 PolarHBondContact O-N 2.89Å; I180-A183 VanDerWaalsContact O-N 3.16Å; G181-A183 VanDerWaalsContact C-N 3.31Å; G181-A183 PolarHBondContact O-N 3.4Å; A183-G187 PolarHBondContact O-N 3.46Å
184F96.3Very high95.8Very high49 Ų4926.8 Ų26.822%0.21514%0.137CC..Hα-helixtrans-57.9-52.6171.3-87.3-82.5000112.4L32 L36 V157 I180 G181 V182 L186 G187 F188L32-F184 HydrophobicContact CD2-CD2 4.27Å; L32-F184 HydrophobicContact CD2-CE2 3.92Å; L36-F184 HydrophobicContact CD1-CB 4.33Å; L36-F184 HydrophobicContact CD1-CD1 3.89Å; L36-F184 HydrophobicContact CD1-CD2 3.94Å; L36-F184 HydrophobicContact CD1-CE1 4.06Å; L36-F184 HydrophobicContact CD1-CE2 4.12Å; L36-F184 HydrophobicContact CD1-CG 3.8Å; L36-F184 HydrophobicContact CD1-CZ 4.15Å; L36-F184 HydrophobicContact CD2-CD1 4.06Å; L36-F184 HydrophobicContact CD2-CE1 3.63Å; L36-F184 HydrophobicContact CD2-CZ 4Å; V157-F184 HydrophobicContact CB-CZ 4.44Å; V157-F184 HydrophobicContact CG1-CE2 3.88Å; V157-F184 HydrophobicContact CG1-CZ 3.55Å; V157-F184 HydrophobicContact CG2-CZ 3.98Å; I180-F184 HydrophobicContact CG2-CD2 3.98Å; I180-F184 HydrophobicContact CG2-CE2 3.99Å; I180-F184 WeakPolarHBondContact O-CD2 3.25Å; I180-F184 PolarHBondContact O-N 3.3Å; I180-F184 VanDerWaalsContact O-N 3.07Å; G181-F184 WeakPolarHBondContact O-CB 3.47Å; G181-F184 PolarHBondContact O-N 3.32Å; G181-F184 VanDerWaalsContact O-N 3.15Å; V182-F184 VanDerWaalsContact C-N 3.34Å; V182-F184 PolarHBondContact O-N 2.83Å; F184-L186 PolarHBondContact O-N 3.34Å; F184-G187 PolarHBondContact O-N 3.14Å; F184-F188 AromaticContact CD1-CD2 4Å; F184-F188 HydrophobicContact CD1-CD2 4Å; F184-F188 AromaticContact CD1-CE2 3.57Å; F184-F188 HydrophobicContact CD1-CE2 3.57Å; F184-F188 AromaticContact CE1-CE2 3.9Å; F184-F188 HydrophobicContact CE1-CE2 3.9Å; F184-F188 WeakPolarHBondContact O-CB 3.08Å; F184-F188 WeakPolarHBondContact O-CD2 3.27Å; F184-F188 PolarHBondContact O-N 3.29Å
185S96.6Very high95.7Very high7 Ų726.1 Ų26.15%0.04913%0.133CC..Hα-helixtrans-60.4-46.7-178.5-61.70000111.8G181 V182 T189 G325 M328 Q332G181-S185 PolarHBondContact O-N 3.16Å; G181-S185 PolarHBondContact O-OG 3.3Å; V182-S185 PolarHBondContact O-N 2.9Å; S185-T189 VanDerWaalsContact O-CB 3.22Å; S185-T189 WeakPolarHBondContact O-CB 3.45Å; S185-T189 PolarHBondContact O-N 3.35Å; S185-T189 VanDerWaalsContact O-N 3.09Å; S185-T189 PolarHBondContact O-OG1 2.91Å; S185-G325 WeakPolarHBondContact CB-O 3.16Å; S185-M328 WeakPolarHBondContact OG-CB 3.22Å; S185-Q332 PolarHBondContact OG-OE1 2.98Å
186L97.1Very high95.5Very high43 Ų4325.6 Ų25.623%0.22514%0.137CC..Hα-helixtrans-68.8-43.8178.8-67.8178.4000112.7F29 L33 V182 F184 T189 L190 A329F29-L186 HydrophobicContact CZ-CD1 4.36Å; L33-L186 HydrophobicContact CD1-CB 3.73Å; V182-L186 HydrophobicContact CG1-CD1 3.82Å; V182-L186 HydrophobicContact CG1-CG 4.15Å; V182-L186 WeakPolarHBondContact O-CB 3.45Å; V182-L186 WeakPolarHBondContact O-CG 3.44Å; V182-L186 PolarHBondContact O-N 3.21Å; F184-L186 PolarHBondContact O-N 3.34Å; L186-T189 PolarHBondContact O-N 3.3Å; L186-L190 WeakPolarHBondContact O-CB 3.4Å; L186-L190 WeakPolarHBondContact O-CG 3.33Å; L186-L190 PolarHBondContact O-N 3.4Å; L186-A329 HydrophobicContact CD2-CB 3.95Å; L186-A329 HydrophobicContact CG-CB 4.19Å
187G96.6Very high95.3Very high0 Ų032.4 Ų32.40%016%0.163CC..Hα-helixtrans-61.9-46.5-179.900000112.4A40 A183 F184 T189 G191A40-G187 WeakPolarHBondContact CB-O 3.47Å; A183-G187 PolarHBondContact O-N 3.46Å; F184-G187 PolarHBondContact O-N 3.14Å; G187-T189 VanDerWaalsContact C-N 3.28Å; G187-T189 PolarHBondContact O-N 3.18Å; G187-G191 WeakPolarHBondContact O-CA 3.37Å; G187-G191 PolarHBondContact O-N 3.06Å
188F93.6Very high95.1Very high81 Ų8133.9 Ų33.936%0.35517%0.171SC..Hα-helixtrans-75.4-13.8177.1-79.5-99.4000113.8L36 F39 L43 F184 P192L36-F188 HydrophobicContact CD2-CE2 3.92Å; F39-F188 HydrophobicContact CD1-CE1 4.43Å; F39-F188 AromaticContact CD1-CZ 3.93Å; F39-F188 HydrophobicContact CD1-CZ 3.93Å; F39-F188 HydrophobicContact CE1-CE1 4.05Å; F39-F188 AromaticContact CE1-CZ 3.71Å; F39-F188 HydrophobicContact CE1-CZ 3.71Å; L43-F188 HydrophobicContact CD1-CD1 3.55Å; L43-F188 HydrophobicContact CD1-CE1 3.62Å; F184-F188 AromaticContact CD1-CD2 4Å; F184-F188 HydrophobicContact CD1-CD2 4Å; F184-F188 AromaticContact CD1-CE2 3.57Å; F184-F188 HydrophobicContact CD1-CE2 3.57Å; F184-F188 AromaticContact CE1-CE2 3.9Å; F184-F188 HydrophobicContact CE1-CE2 3.9Å; F184-F188 WeakPolarHBondContact O-CB 3.08Å; F184-F188 WeakPolarHBondContact O-CD2 3.27Å; F184-F188 PolarHBondContact O-N 3.29Å; F188-P192 WeakPolarHBondContact O-CD 3.47Å; F188-P192 VanDerWaalsContact O-CG 3.25Å; F188-P192 WeakPolarHBondContact O-CG 3.18Å
189T94.8Very high94.7Very high5 Ų534.7 Ų34.73%0.03118%0.178CC..Hα-helixtrans-84.1-53.9172.1-62.70000111.1S185 L186 G187 M193 F322 G325 I326S185-T189 VanDerWaalsContact O-CB 3.22Å; S185-T189 WeakPolarHBondContact O-CB 3.45Å; S185-T189 PolarHBondContact O-N 3.35Å; S185-T189 VanDerWaalsContact O-N 3.09Å; S185-T189 PolarHBondContact O-OG1 2.91Å; L186-T189 PolarHBondContact O-N 3.3Å; G187-T189 VanDerWaalsContact C-N 3.28Å; G187-T189 PolarHBondContact O-N 3.18Å; T189-M193 WeakPolarHBondContact O-CG 3.23Å; T189-F322 HydrophobicContact CG2-CD2 3.21Å; T189-F322 HydrophobicContact CG2-CE2 3.49Å; T189-F322 VanDerWaalsContact CG2-CE2 3.49Å; T189-F322 HydrophobicContact CG2-CG 4.07Å; T189-G325 VanDerWaalsContact OG1-CA 3.27Å; T189-G325 WeakPolarHBondContact OG1-CA 3.45Å; T189-I326 HydrophobicContact CG2-CD1 3.86Å; T189-I326 HydrophobicContact CG2-CG1 3.92Å
190L95.3Very high94.2Very high70 Ų7040.3 Ų40.337%0.36621%0.206SC..Hα-helixtrans-83-36.6-171.2-61.4176.7000112.2L37 L186 M193 I194L37-L190 HydrophobicContact CD2-CB 3.73Å; L186-L190 WeakPolarHBondContact O-CB 3.4Å; L186-L190 WeakPolarHBondContact O-CG 3.33Å; L186-L190 PolarHBondContact O-N 3.4Å; L190-M193 PolarHBondContact O-N 2.91Å; L190-I194 VanDerWaalsContact O-CG1 3.31Å; L190-I194 WeakPolarHBondContact O-CG1 3.48Å; L190-I194 PolarHBondContact O-N 3.02Å
191G95.4Very high93.7Very high0 Ų044.6 Ų44.60%023%0.225CC..Hα-helixtrans-57.1-52.5-178.800000112.9L41 G187 M193 I194 G195L41-G191 WeakPolarHBondContact CD2-O 3.47Å; G187-G191 WeakPolarHBondContact O-CA 3.37Å; G187-G191 PolarHBondContact O-N 3.06Å; G191-M193 VanDerWaalsContact C-N 3.3Å; G191-M193 PolarHBondContact O-N 3.24Å; G191-I194 PolarHBondContact O-N 2.93Å; G191-G195 PolarHBondContact O-N 3.32Å
192P93.1Very high93.1Very high28 Ų2845.6 Ų45.618%0.18223%0.233CC..Hα-helixtrans-61-37.6177.6-27.739.7000112.9A40 L43 P44 F188 I194 G195 A196A40-P192 HydrophobicContact CB-CG 4.24Å; L43-P192 HydrophobicContact CB-CG 4.37Å; L43-P192 HydrophobicContact CD1-CG 4.23Å; P44-P192 HydrophobicContact CG-CB 4.08Å; P44-P192 WeakPolarHBondContact CG-O 3.39Å; F188-P192 WeakPolarHBondContact O-CD 3.47Å; F188-P192 VanDerWaalsContact O-CG 3.25Å; F188-P192 WeakPolarHBondContact O-CG 3.18Å; P192-I194 PolarHBondContact O-N 3.4Å; P192-G195 PolarHBondContact O-N 2.86Å; P192-A196 VanDerWaalsContact O-CB 3.31Å; P192-A196 WeakPolarHBondContact O-CB 3.46Å; P192-A196 PolarHBondContact O-N 3.4Å
193M91.8Very high92.3Very high100 Ų10051.5 Ų51.549%0.49326%0.259SS..Hα-helixtrans-61.5-47.9177.3-67.9177.569.400111.8T189 L190 G191 G195 Y197 F322T189-M193 WeakPolarHBondContact O-CG 3.23Å; L190-M193 PolarHBondContact O-N 2.91Å; G191-M193 VanDerWaalsContact C-N 3.3Å; G191-M193 PolarHBondContact O-N 3.24Å; M193-G195 VanDerWaalsContact C-N 3.34Å; M193-Y197 WeakPolarHBondContact O-CB 3.38Å; M193-Y197 PolarHBondContact O-N 3.3Å; M193-F322 HydrophobicContact CE-CD2 4.29Å; M193-F322 HydrophobicContact CE-CE2 4.13Å; M193-F322 HydrophobicContact CG-CD2 4.44Å; M193-F322 HydrophobicContact SD-CD2 3.2Å; M193-F322 WeakPolarHBondContact SD-CD2 3.44Å; M193-F322 HydrophobicContact SD-CE2 3.34Å; M193-F322 WeakPolarHBondContact SD-CE2 3.47Å; M193-F322 HydrophobicContact SD-CG 4.3Å
194I94.3Very high91.1Very high59 Ų5962.1 Ų62.130%0.30331%0.305SS..Hα-helixtrans-64.4-42.7178.7-61.7163.8000109.9L41 L190 G191 P192 A196 Y197 L198 L215L41-I194 HydrophobicContact CD2-CB 3.7Å; L41-I194 HydrophobicContact CD2-CG2 3.57Å; L190-I194 VanDerWaalsContact O-CG1 3.31Å; L190-I194 WeakPolarHBondContact O-CG1 3.48Å; L190-I194 PolarHBondContact O-N 3.02Å; G191-I194 PolarHBondContact O-N 2.93Å; P192-I194 PolarHBondContact O-N 3.4Å; I194-A196 PolarHBondContact O-N 3.23Å; I194-Y197 PolarHBondContact O-N 3.29Å; I194-L198 HydrophobicContact CG2-CD1 4.02Å; I194-L198 HydrophobicContact CG2-CG 4.38Å; I194-L198 WeakPolarHBondContact O-CG 3.16Å; I194-L198 PolarHBondContact O-N 3.49Å; I194-L215 HydrophobicContact CG2-CD2 3.61Å
195G93.2Very high89.9Confident0 Ų064 Ų640%034%0.339CS..Hα-helixtrans-65-41-178.400000113L41 G191 P192 M193 A199 S212L41-G195 VanDerWaalsContact CD2-N 3.35Å; L41-G195 WeakPolarHBondContact O-CA 3.5Å; G191-G195 PolarHBondContact O-N 3.32Å; P192-G195 PolarHBondContact O-N 2.86Å; M193-G195 VanDerWaalsContact C-N 3.34Å; G195-A199 PolarHBondContact O-N 3.44Å; G195-S212 PolarHBondContact O-OG 3.39Å
196A90.5Very high89.3Confident34 Ų3466.4 Ų66.428%0.28135%0.349SS..Hα-helixtrans-66.8-43.5174.900000111.7P44 P192 I194 A199 M200P44-A196 HydrophobicContact CB-CB 4.22Å; P44-A196 HydrophobicContact CG-CB 4.06Å; P192-A196 VanDerWaalsContact O-CB 3.31Å; P192-A196 WeakPolarHBondContact O-CB 3.46Å; P192-A196 PolarHBondContact O-N 3.4Å; I194-A196 PolarHBondContact O-N 3.23Å; A196-A199 PolarHBondContact O-N 2.86Å; A196-M200 WeakPolarHBondContact O-CG 3.35Å; A196-M200 PolarHBondContact O-N 3.45Å; A196-M200 VanDerWaalsContact O-N 3.11Å
197Y91.6Very high88.7Confident142 Ų14265.5 Ų65.556%0.55735%0.346SS*.Hα-helixtrans-59.2-49.1177.4175.3-99.7000111.9M193 I194 A199 M200 E201M193-Y197 WeakPolarHBondContact O-CB 3.38Å; M193-Y197 PolarHBondContact O-N 3.3Å; I194-Y197 PolarHBondContact O-N 3.29Å; Y197-A199 PolarHBondContact O-N 2.89Å; Y197-M200 PolarHBondContact O-N 3.36Å; Y197-M200 VanDerWaalsContact O-N 3.11Å; Y197-E201 HydrophobicContact CE1-CG 4.16Å; Y197-E201 HydrophobicContact CE2-CG 4.17Å; Y197-E201 PolarHBondContact O-N 3.31Å
198L92.3Very high88.5Confident34 Ų3467.4 Ų67.418%0.17835%0.354CS..Hα-helixtrans-62-32.1180-71.8175.5000113.5I194 R211 S212 L215I194-L198 HydrophobicContact CG2-CD1 4.02Å; I194-L198 HydrophobicContact CG2-CG 4.38Å; I194-L198 WeakPolarHBondContact O-CG 3.16Å; I194-L198 PolarHBondContact O-N 3.49Å; L198-R211 HydrophobicContact CB-CB 4.24Å; L198-R211 HydrophobicContact CD2-CB 4.44Å; L198-S212 WeakPolarHBondContact CB-OG 3.4Å; L198-L215 HydrophobicContact CD1-CB 4.19Å; L198-L215 HydrophobicContact CD1-CD2 3.62Å
199A88.6Confident88.4Confident19 Ų1963.6 Ų63.616%0.15734%0.337CS..Hα-helixtrans-76-29176.200000113.7L45 G195 A196 Y197 E201 A202 F208L45-A199 HydrophobicContact CD2-CB 3.21Å; G195-A199 PolarHBondContact O-N 3.44Å; A196-A199 PolarHBondContact O-N 2.86Å; Y197-A199 PolarHBondContact O-N 2.89Å; A199-E201 VanDerWaalsContact C-N 3.35Å; A199-A202 WeakPolarHBondContact O-CB 3.42Å; A199-F208 WeakPolarHBondContact CA-O 3.49Å; A199-F208 HydrophobicContact CB-CD2 3.94Å
200M87Confident88.4Confident143 Ų14365 Ų6570%0.70434%0.344SS*.Hα-helixtrans-71.3-32.8174.6-71.2178.162.700112A196 Y197 A202A196-M200 WeakPolarHBondContact O-CG 3.35Å; A196-M200 PolarHBondContact O-N 3.45Å; A196-M200 VanDerWaalsContact O-N 3.11Å; Y197-M200 PolarHBondContact O-N 3.36Å; Y197-M200 VanDerWaalsContact O-N 3.11Å; M200-A202 PolarHBondContact O-N 2.95Å
201E87.5Confident88.4Confident102 Ų10265 Ų6548%0.47734%0.339SS..THydrogen-bonded Turntrans-82.46.3178.4-68.1-62.9138.100113.8Y197 A199 E203 R211Y197-E201 HydrophobicContact CE1-CG 4.16Å; Y197-E201 HydrophobicContact CE2-CG 4.17Å; Y197-E201 PolarHBondContact O-N 3.31Å; A199-E201 VanDerWaalsContact C-N 3.35Å; E201-E203 PolarHBondContact O-N 3.41Å; E201-R211 PolarHBondContact O-NH1 3.22Å
202A83.8Confident88.4Confident28 Ų2865 Ų6523%0.23134%0.339CS..  trans-67.9129.9179.700000111.3A199 M200 F208A199-A202 WeakPolarHBondContact O-CB 3.42Å; M200-A202 PolarHBondContact O-N 2.95Å; A202-F208 HydrophobicContact CB-CB 3.96Å
203E81.8Confident88.5Confident138 Ų13863.7 Ų63.765%0.64533%0.331SS*.  trans-73156.3179.7-73.7170.4-140.500112.1E201 G205 E206 R211E201-E203 PolarHBondContact O-N 3.41Å; E203-G205 PolarHBondContact O-N 2.99Å; E203-E206 WeakPolarHBondContact O-CB 3.26Å; E203-E206 PolarHBondContact O-N 3.46Å; E203-R211 IonicContact OE1-NH2 3.26Å; E203-R211 PolarHBondContact OE1-NH2 3.25Å; E203-R211 VanDerWaalsContact OE1-NH2 3.12Å
204K72.2Confident88.8Confident222 Ų22263 Ų6397%0.96533%0.329SS*.THydrogen-bonded Turntrans-60.8114.6176.7-73.9-175.9179.9177.90110
205G71.6Confident88.9Confident89 Ų8961.9 Ų61.992%0.91832%0.323SS*.THydrogen-bonded Turntrans105-13.8-178.800000114E203E203-G205 PolarHBondContact O-N 2.99Å
206E82.6Confident89.2Confident58 Ų5861.9 Ų61.927%0.27132%0.323SS..SBendtrans-80.5144.1170.5-163.5-179.1167.900110.3E203 F208 L210 R211E203-E206 WeakPolarHBondContact O-CB 3.26Å; E203-E206 PolarHBondContact O-N 3.46Å; E206-F208 PolarHBondContact O-N 3.3Å; E206-L210 HydrophobicContact CG-CD2 4.27Å; E206-R211 VanDerWaalsContact OE1-CG 3.25Å; E206-R211 WeakPolarHBondContact OE1-CG 3.34Å; E206-R211 IonicContact OE1-NE 3.19Å; E206-R211 PolarHBondContact OE1-NE 3.1Å; E206-R211 IonicContact OE2-CZ 3.86Å; E206-R211 VanDerWaalsContact OE2-CZ 3.28Å; E206-R211 IonicContact OE2-NE 2.78Å; E206-R211 PolarHBondContact OE2-NE 2.94Å; E206-R211 IonicContact OE2-NH2 3.89Å; E206-R211 PolarHBondContact OE2-NH2 3.34Å
207V86.1Confident89.5Confident24 Ų2462.1 Ų62.115%0.14532%0.32CS..  trans-70.4114.2169.7-179.90000108F209 L210V207-F209 HydrophobicContact CG1-CD1 3.51Å; V207-F209 HydrophobicContact CG1-CD2 4.03Å; V207-F209 HydrophobicContact CG1-CE1 3.17Å; V207-F209 HydrophobicContact CG1-CE2 3.72Å; V207-F209 HydrophobicContact CG1-CG 3.95Å; V207-F209 HydrophobicContact CG1-CZ 3.29Å; V207-F209 PolarHBondContact O-N 3.42Å; V207-L210 HydrophobicContact CB-CB 4.45Å; V207-L210 WeakPolarHBondContact O-CB 3.4Å; V207-L210 PolarHBondContact O-N 3.02Å
208F90.8Very high89.8Confident40 Ų4061.3 Ų61.318%0.17532%0.322CS..THydrogen-bonded Turntrans-54.6-26.1-168.873.7-85.4000115.6L45 S48 I49 Y52 A199 A202 E206L45-F208 HydrophobicContact CB-CE2 4.33Å; L45-F208 HydrophobicContact CD2-CD2 4.31Å; L45-F208 HydrophobicContact CD2-CE2 4.13Å; S48-F208 VanDerWaalsContact C-CZ 3.47Å; I49-F208 HydrophobicContact CB-CZ 4.32Å; I49-F208 HydrophobicContact CG1-CE2 4.03Å; I49-F208 HydrophobicContact CG1-CZ 3.59Å; Y52-F208 HydrophobicContact CD2-CE1 4.42Å; Y52-F208 HydrophobicContact CG-CE1 4.25Å; A199-F208 WeakPolarHBondContact CA-O 3.49Å; A199-F208 HydrophobicContact CB-CD2 3.94Å; A202-F208 HydrophobicContact CB-CB 3.96Å; E206-F208 PolarHBondContact O-N 3.3Å
209F92.6Very high90.1Very high0 Ų061.8 Ų61.80%032%0.323CS..THydrogen-bonded Turntrans-88.9-5.5179.461.8-105.7000114.2L45 I49 Y52 W134 V207 S212 A213L45-F209 HydrophobicContact CD1-CB 4.24Å; I49-F209 HydrophobicContact CD1-CB 4.1Å; I49-F209 HydrophobicContact CD1-CD1 4.31Å; I49-F209 HydrophobicContact CD1-CG 4.28Å; I49-F209 HydrophobicContact CG1-CB 4.22Å; I49-F209 HydrophobicContact CG1-CD1 3.79Å; I49-F209 HydrophobicContact CG1-CE1 4.46Å; I49-F209 HydrophobicContact CG1-CG 4.22Å; Y52-F209 HydrophobicContact CD1-CE1 4.25Å; Y52-F209 HydrophobicContact CE1-CE1 4.38Å; W134-F209 HydrophobicContact CZ2-CB 4.15Å; W134-F209 AromaticContact NE1-CD2 3.43Å; W134-F209 AromaticContact NE1-CE2 3.83Å; V207-F209 HydrophobicContact CG1-CD1 3.51Å; V207-F209 HydrophobicContact CG1-CD2 4.03Å; V207-F209 HydrophobicContact CG1-CE1 3.17Å; V207-F209 HydrophobicContact CG1-CE2 3.72Å; V207-F209 HydrophobicContact CG1-CG 3.95Å; V207-F209 HydrophobicContact CG1-CZ 3.29Å; V207-F209 PolarHBondContact O-N 3.42Å; F209-S212 PolarHBondContact O-N 2.91Å; F209-A213 PolarHBondContact O-N 2.98Å
210L94.3Very high90.6Very high35 Ų3561 Ų6118%0.18332%0.316CS..Hα-helixtrans-62.1-48.9-172.8179.159.7000112.2A135 E206 V207 S212 A213 L214A135-L210 HydrophobicContact CB-CD1 4.19Å; A135-L210 WeakPolarHBondContact O-CD1 3.35Å; E206-L210 HydrophobicContact CG-CD2 4.27Å; V207-L210 HydrophobicContact CB-CB 4.45Å; V207-L210 WeakPolarHBondContact O-CB 3.4Å; V207-L210 PolarHBondContact O-N 3.02Å; L210-S212 VanDerWaalsContact C-N 3.29Å; L210-S212 PolarHBondContact O-N 2.95Å; L210-A213 WeakPolarHBondContact O-CB 3.31Å; L210-A213 PolarHBondContact O-N 2.89Å; L210-A213 VanDerWaalsContact O-N 3.09Å; L210-L214 HydrophobicContact CD1-CD1 4.21Å; L210-L214 HydrophobicContact CD1-CG 4.14Å; L210-L214 HydrophobicContact CG-CD1 4.11Å; L210-L214 HydrophobicContact CG-CG 4.45Å; L210-L214 WeakPolarHBondContact O-CG 3.3Å; L210-L214 PolarHBondContact O-N 3.14Å
211R94.8Very high91.1Very high70 Ų7057 Ų5726%0.26430%0.3SS..Hα-helixtrans-58.1-42.2178.1-60.3-175.7-176.2-170.7-3.2111.7L198 E201 E203 E206 L214 L215L198-R211 HydrophobicContact CB-CB 4.24Å; L198-R211 HydrophobicContact CD2-CB 4.44Å; E201-R211 PolarHBondContact O-NH1 3.22Å; E203-R211 IonicContact OE1-NH2 3.26Å; E203-R211 PolarHBondContact OE1-NH2 3.25Å; E203-R211 VanDerWaalsContact OE1-NH2 3.12Å; E206-R211 VanDerWaalsContact OE1-CG 3.25Å; E206-R211 WeakPolarHBondContact OE1-CG 3.34Å; E206-R211 IonicContact OE1-NE 3.19Å; E206-R211 PolarHBondContact OE1-NE 3.1Å; E206-R211 IonicContact OE2-CZ 3.86Å; E206-R211 VanDerWaalsContact OE2-CZ 3.28Å; E206-R211 IonicContact OE2-NE 2.78Å; E206-R211 PolarHBondContact OE2-NE 2.94Å; E206-R211 IonicContact OE2-NH2 3.89Å; E206-R211 PolarHBondContact OE2-NH2 3.34Å; R211-L214 PolarHBondContact O-N 3.38Å; R211-L215 WeakPolarHBondContact O-CB 3.44Å; R211-L215 PolarHBondContact O-N 3.26Å
212S95.6Very high91.6Very high0 Ų054.1 Ų54.10%029%0.294CS..Hα-helixtrans-65-39.2175.9-58.60000112.2G195 L198 F209 L210 A216G195-S212 PolarHBondContact O-OG 3.39Å; L198-S212 WeakPolarHBondContact CB-OG 3.4Å; F209-S212 PolarHBondContact O-N 2.91Å; L210-S212 VanDerWaalsContact C-N 3.29Å; L210-S212 PolarHBondContact O-N 2.95Å; S212-A216 WeakPolarHBondContact O-CB 3.26Å; S212-A216 PolarHBondContact O-N 3.1Å
213A96.3Very high92.3Very high0 Ų052.9 Ų52.90%028%0.283CS..Hα-helixtrans-67.3-41.7175.900000112.7W134 A135 F209 L210 A216 L217W134-A213 HydrophobicContact CB-CB 4.49Å; W134-A213 HydrophobicContact CD2-CB 3.55Å; W134-A213 HydrophobicContact CE3-CB 3.55Å; W134-A213 HydrophobicContact CG-CB 4Å; W134-A213 HydrophobicContact CH2-CB 4.25Å; W134-A213 HydrophobicContact CZ2-CB 4.25Å; W134-A213 VanDerWaalsContact CZ3-CA 3.5Å; W134-A213 HydrophobicContact CZ3-CB 3.93Å; A135-A213 HydrophobicContact CB-CB 3.93Å; F209-A213 PolarHBondContact O-N 2.98Å; L210-A213 WeakPolarHBondContact O-CB 3.31Å; L210-A213 PolarHBondContact O-N 2.89Å; L210-A213 VanDerWaalsContact O-N 3.09Å; A213-A216 PolarHBondContact O-N 3.46Å; A213-L217 WeakPolarHBondContact O-CB 3.42Å; A213-L217 PolarHBondContact O-N 2.85Å
214L97Very high93.1Very high86 Ų8647.8 Ų47.845%0.4526%0.26SS..Hα-helixtrans-66.1-39.3176.1-69.3175.7000111.9A135 L210 R211 L217 M218A135-L214 HydrophobicContact CB-CD2 4.01Å; L210-L214 HydrophobicContact CD1-CD1 4.21Å; L210-L214 HydrophobicContact CD1-CG 4.14Å; L210-L214 HydrophobicContact CG-CD1 4.11Å; L210-L214 HydrophobicContact CG-CG 4.45Å; L210-L214 WeakPolarHBondContact O-CG 3.3Å; L210-L214 PolarHBondContact O-N 3.14Å; R211-L214 PolarHBondContact O-N 3.38Å; L214-L217 WeakPolarHBondContact O-CB 3.37Å; L214-L217 PolarHBondContact O-N 2.88Å; L214-M218 WeakPolarHBondContact O-CB 3.41Å; L214-M218 PolarHBondContact O-N 3.04Å
215L97.6Very high94.3Very high36 Ų3641.4 Ų41.419%0.18824%0.236CC..Hα-helixtrans-66.4-40.6174.3-176.962.4000111.7L41 I194 L198 R211 L217 M218 F219L41-L215 HydrophobicContact CD1-CB 4.02Å; L41-L215 HydrophobicContact CD1-CD2 4Å; L41-L215 HydrophobicContact CD1-CG 3.91Å; L41-L215 HydrophobicContact CD2-CD2 4.1Å; I194-L215 HydrophobicContact CG2-CD2 3.61Å; L198-L215 HydrophobicContact CD1-CB 4.19Å; L198-L215 HydrophobicContact CD1-CD2 3.62Å; R211-L215 WeakPolarHBondContact O-CB 3.44Å; R211-L215 PolarHBondContact O-N 3.26Å; L215-L217 VanDerWaalsContact C-N 3.31Å; L215-L217 PolarHBondContact O-N 3.32Å; L215-M218 HydrophobicContact CD1-SD 4.23Å; L215-M218 WeakPolarHBondContact O-CB 3.32Å; L215-M218 PolarHBondContact O-N 3.38Å; L215-F219 HydrophobicContact CD1-CD2 4.45Å; L215-F219 HydrophobicContact CD1-CE1 4.25Å; L215-F219 HydrophobicContact CD1-CE2 4.01Å; L215-F219 HydrophobicContact CD1-CZ 3.9Å; L215-F219 HydrophobicContact CD2-CE2 3.92Å; L215-F219 HydrophobicContact CD2-CZ 4.22Å; L215-F219 HydrophobicContact CG-CD2 4.09Å; L215-F219 HydrophobicContact CG-CE2 3.69Å; L215-F219 HydrophobicContact CG-CZ 4.07Å; L215-F219 PolarHBondContact O-N 3.4Å
216A97.8Very high95.6Very high0 Ų039.3 Ų39.30%020%0.202CC..Hα-helixtrans-60.3-41.617400000111.9G38 L41 Y131 W134 S212 A213 F219 A220G38-A216 WeakPolarHBondContact O-CB 3.26Å; L41-A216 HydrophobicContact CD1-CB 3.93Å; Y131-A216 HydrophobicContact CD1-CB 3.81Å; Y131-A216 HydrophobicContact CD2-CB 4.17Å; Y131-A216 WeakPolarHBondContact CD2-O 3.46Å; Y131-A216 HydrophobicContact CE1-CB 4.04Å; Y131-A216 HydrophobicContact CE2-CB 4.38Å; Y131-A216 HydrophobicContact CG-CB 3.89Å; W134-A216 HydrophobicContact CE3-CB 4.49Å; W134-A216 HydrophobicContact CZ3-CB 4.01Å; S212-A216 WeakPolarHBondContact O-CB 3.26Å; S212-A216 PolarHBondContact O-N 3.1Å; A213-A216 PolarHBondContact O-N 3.46Å; A216-F219 PolarHBondContact O-N 3.4Å; A216-A220 PolarHBondContact O-N 3.31Å
217L98.3Very high96.2Very high39 Ų3936.6 Ų36.620%0.20419%0.189CC..Hα-helixtrans-62.3-45.2174.1179.161.2000111.6I128 A132 A213 L214 L215 F219 A220 V221I128-L217 HydrophobicContact CB-CD1 4.36Å; I128-L217 HydrophobicContact CG2-CD1 3.72Å; I128-L217 WeakPolarHBondContact O-CD1 3.25Å; A132-L217 HydrophobicContact CB-CD1 4.28Å; A132-L217 HydrophobicContact CB-CD2 4.4Å; A213-L217 WeakPolarHBondContact O-CB 3.42Å; A213-L217 PolarHBondContact O-N 2.85Å; L214-L217 WeakPolarHBondContact O-CB 3.37Å; L214-L217 PolarHBondContact O-N 2.88Å; L215-L217 VanDerWaalsContact C-N 3.31Å; L215-L217 PolarHBondContact O-N 3.32Å; L217-F219 VanDerWaalsContact C-N 3.35Å; L217-F219 PolarHBondContact O-N 3.34Å; L217-A220 PolarHBondContact O-N 2.89Å; L217-V221 HydrophobicContact CD1-CG2 4.42Å; L217-V221 WeakPolarHBondContact O-CG2 3.3Å; L217-V221 PolarHBondContact O-N 3.29Å
218M98.3Very high96.8Very high124 Ų12440.3 Ų40.361%0.61120%0.204SC*.Hα-helixtrans-59.3-45176.2-175-168.5-6200111.5L214 L215 A220 V221 A222L214-M218 WeakPolarHBondContact O-CB 3.41Å; L214-M218 PolarHBondContact O-N 3.04Å; L215-M218 HydrophobicContact CD1-SD 4.23Å; L215-M218 WeakPolarHBondContact O-CB 3.32Å; L215-M218 PolarHBondContact O-N 3.38Å; M218-A220 PolarHBondContact O-N 3.21Å; M218-V221 PolarHBondContact O-N 2.8Å; M218-A222 WeakPolarHBondContact O-CB 3.26Å; M218-A222 PolarHBondContact O-N 3.33Å
219F98.3Very high97.1Very high44 Ų4445.4 Ų45.419%0.19323%0.226CC..Hα-helixtrans-61.8-41.9175-73.4-35.1000112.2I34 L37 L41 L215 A216 L217 V221 A222 D223I34-F219 HydrophobicContact CG2-CB 3.85Å; I34-F219 HydrophobicContact CG2-CD1 4.22Å; I34-F219 HydrophobicContact CG2-CG 4.33Å; I34-F219 WeakPolarHBondContact CG2-O 3.33Å; L37-F219 HydrophobicContact CB-CD2 4.09Å; L37-F219 HydrophobicContact CB-CE2 3.97Å; L41-F219 HydrophobicContact CD1-CD2 4.14Å; L41-F219 HydrophobicContact CD1-CE2 4.18Å; L215-F219 HydrophobicContact CD1-CD2 4.45Å; L215-F219 HydrophobicContact CD1-CE1 4.25Å; L215-F219 HydrophobicContact CD1-CE2 4.01Å; L215-F219 HydrophobicContact CD1-CZ 3.9Å; L215-F219 HydrophobicContact CD2-CE2 3.92Å; L215-F219 HydrophobicContact CD2-CZ 4.22Å; L215-F219 HydrophobicContact CG-CD2 4.09Å; L215-F219 HydrophobicContact CG-CE2 3.69Å; L215-F219 HydrophobicContact CG-CZ 4.07Å; L215-F219 PolarHBondContact O-N 3.4Å; A216-F219 PolarHBondContact O-N 3.4Å; L217-F219 VanDerWaalsContact C-N 3.35Å; L217-F219 PolarHBondContact O-N 3.34Å; F219-V221 PolarHBondContact O-N 3.48Å; F219-A222 PolarHBondContact O-N 3.11Å; F219-D223 WeakPolarHBondContact O-CB 3.09Å; F219-D223 PolarHBondContact O-N 3.2Å
220A98.1Very high97.3Very high2 Ų249 Ų492%0.01725%0.245CC..Hα-helixtrans-65.6-38.4177.400000113.2V124 I128 Y131 A216 L217 M218 D223 L224V124-A220 WeakPolarHBondContact CG1-O 3.36Å; I128-A220 HydrophobicContact CG1-CB 3.68Å; Y131-A220 HydrophobicContact CD2-CB 3.61Å; Y131-A220 HydrophobicContact CE2-CB 3.81Å; A216-A220 PolarHBondContact O-N 3.31Å; L217-A220 PolarHBondContact O-N 2.89Å; M218-A220 PolarHBondContact O-N 3.21Å; A220-D223 PolarHBondContact O-N 3.28Å; A220-L224 WeakPolarHBondContact O-CB 3.44Å; A220-L224 PolarHBondContact O-N 3.04Å
221V98.4Very high97.4Very high60 Ų6047.6 Ų47.636%0.36424%0.237SC..Hα-helixtrans-66.5-43.1173.6173.50000110.6I128 L217 M218 F219 D223 L224 L225I128-V221 HydrophobicContact CD1-CG2 4Å; I128-V221 HydrophobicContact CG1-CG2 4.15Å; I128-V221 HydrophobicContact CG2-CG2 4.34Å; L217-V221 HydrophobicContact CD1-CG2 4.42Å; L217-V221 WeakPolarHBondContact O-CG2 3.3Å; L217-V221 PolarHBondContact O-N 3.29Å; M218-V221 PolarHBondContact O-N 2.8Å; F219-V221 PolarHBondContact O-N 3.48Å; V221-D223 VanDerWaalsContact C-N 3.33Å; V221-D223 PolarHBondContact O-N 3.41Å; V221-L224 WeakPolarHBondContact O-CB 3.29Å; V221-L224 PolarHBondContact O-N 2.83Å; V221-L225 HydrophobicContact CG1-CD1 4.28Å; V221-L225 WeakPolarHBondContact O-CG 3.47Å; V221-L225 PolarHBondContact O-N 3.5Å
222A98.1Very high97.3Very high42 Ų4246.9 Ų46.935%0.34724%0.242SC..Hα-helixtrans-61.3-42.3175.600000111.6M218 F219 L225 F226M218-A222 WeakPolarHBondContact O-CB 3.26Å; M218-A222 PolarHBondContact O-N 3.33Å; F219-A222 PolarHBondContact O-N 3.11Å; A222-L225 PolarHBondContact O-N 3.35Å; A222-F226 WeakPolarHBondContact O-CB 3.41Å; A222-F226 PolarHBondContact O-N 2.89Å
223D97.6Very high97.3Very high2 Ų249.7 Ų49.71%0.01126%0.255CS..Hα-helixtrans-64.2-42.1176.1-169.634.4000111.7A31 I34 F219 A220 V221 L225 F226 I227A31-D223 WeakPolarHBondContact CA-OD1 3.37Å; A31-D223 VanDerWaalsContact CB-OD1 3.26Å; A31-D223 WeakPolarHBondContact CB-OD1 3.38Å; A31-D223 VanDerWaalsContact O-OD1 3.14Å; I34-D223 HydrophobicContact CB-CB 4.29Å; I34-D223 HydrophobicContact CG2-CB 3.86Å; F219-D223 WeakPolarHBondContact O-CB 3.09Å; F219-D223 PolarHBondContact O-N 3.2Å; A220-D223 PolarHBondContact O-N 3.28Å; V221-D223 VanDerWaalsContact C-N 3.33Å; V221-D223 PolarHBondContact O-N 3.41Å; D223-L225 PolarHBondContact O-N 3.17Å; D223-F226 PolarHBondContact O-N 3.28Å; D223-I227 WeakPolarHBondContact O-CB 3.49Å; D223-I227 VanDerWaalsContact O-CG1 3.3Å; D223-I227 WeakPolarHBondContact O-CG1 3.48Å; D223-I227 PolarHBondContact O-N 3.2Å; D223-I227 WeakPolarHBondContact OD1-CD1 3.38Å
224L98.1Very high97.1Very high31 Ų3151.1 Ų51.116%0.16226%0.264CS..Hα-helixtrans-57.4-51.1174.7-176.776000111.3L121 V124 M125 I128 A220 V221 F226 F228L121-L224 HydrophobicContact CD2-CD1 3.79Å; V124-L224 HydrophobicContact CB-CD1 4.12Å; V124-L224 HydrophobicContact CG1-CB 3.71Å; V124-L224 HydrophobicContact CG1-CD1 4.01Å; V124-L224 HydrophobicContact CG1-CG 4.49Å; M125-L224 HydrophobicContact CG-CD1 3.97Å; M125-L224 HydrophobicContact SD-CD1 3.83Å; M125-L224 HydrophobicContact SD-CD2 3.42Å; M125-L224 WeakPolarHBondContact SD-CD2 3.25Å; M125-L224 HydrophobicContact SD-CG 4.28Å; I128-L224 HydrophobicContact CD1-CB 3.96Å; I128-L224 HydrophobicContact CD1-CD2 3.72Å; I128-L224 HydrophobicContact CD1-CG 4.33Å; A220-L224 WeakPolarHBondContact O-CB 3.44Å; A220-L224 PolarHBondContact O-N 3.04Å; V221-L224 WeakPolarHBondContact O-CB 3.29Å; V221-L224 PolarHBondContact O-N 2.83Å; L224-F226 VanDerWaalsContact C-N 3.34Å; L224-F228 WeakPolarHBondContact O-CB 3.42Å; L224-F228 PolarHBondContact O-N 3.31Å
225L98.1Very high96.8Very high88 Ų8847.1 Ų47.146%0.46124%0.243SC..Hα-helixtrans-62.6-44.6179.2-66.4174.5000110.6V221 A222 D223 F228 F229V221-L225 HydrophobicContact CG1-CD1 4.28Å; V221-L225 WeakPolarHBondContact O-CG 3.47Å; V221-L225 PolarHBondContact O-N 3.5Å; A222-L225 PolarHBondContact O-N 3.35Å; D223-L225 PolarHBondContact O-N 3.17Å; L225-F228 PolarHBondContact O-N 3.39Å; L225-F229 HydrophobicContact CB-CD2 4.45Å; L225-F229 HydrophobicContact CB-CE2 4.43Å; L225-F229 HydrophobicContact CD2-CE2 4.16Å; L225-F229 WeakPolarHBondContact O-CD2 3.16Å; L225-F229 PolarHBondContact O-N 3.11Å
226F98Very high96.4Very high44 Ų4448.1 Ų48.119%0.19325%0.252CS..Hα-helixtrans-59.1-50.6179-177.3-92.7000111.7I27 L30 A31 A222 D223 L224 F229 L230I27-F226 HydrophobicContact CB-CE1 4.47Å; I27-F226 HydrophobicContact CG2-CE1 3.8Å; I27-F226 HydrophobicContact CG2-CZ 4.41Å; I27-F226 WeakPolarHBondContact O-CE1 3.06Å; L30-F226 HydrophobicContact CB-CE1 3.92Å; L30-F226 HydrophobicContact CB-CE2 4.42Å; L30-F226 HydrophobicContact CB-CZ 3.65Å; L30-F226 HydrophobicContact CD1-CE2 4.29Å; L30-F226 HydrophobicContact CD1-CZ 3.85Å; L30-F226 HydrophobicContact CG-CZ 4.41Å; A31-F226 HydrophobicContact CB-CD1 3.96Å; A31-F226 HydrophobicContact CB-CE1 4.06Å; A222-F226 WeakPolarHBondContact O-CB 3.41Å; A222-F226 PolarHBondContact O-N 2.89Å; D223-F226 PolarHBondContact O-N 3.28Å; L224-F226 VanDerWaalsContact C-N 3.34Å; F226-F229 PolarHBondContact O-N 3.28Å; F226-L230 HydrophobicContact CD2-CD1 3.55Å; F226-L230 HydrophobicContact CE1-CD1 4.48Å; F226-L230 HydrophobicContact CE2-CD1 3.29Å; F226-L230 HydrophobicContact CG-CD1 4.24Å; F226-L230 HydrophobicContact CZ-CD1 3.8Å; F226-L230 VanDerWaalsContact O-CB 3.28Å; F226-L230 WeakPolarHBondContact O-CB 3.41Å; F226-L230 PolarHBondContact O-N 3.26Å
227I97.1Very high95.8Very high2 Ų255.7 Ų55.71%0.0129%0.285CS..Hα-helixtrans-63.6-43.3176.4-70167.2000110.8A31 I120 L121 V124 D223 F229 L231A31-I227 HydrophobicContact CB-CD1 4.05Å; A31-I227 HydrophobicContact CB-CG1 3.78Å; I120-I227 HydrophobicContact CD1-CD1 4.22Å; I120-I227 HydrophobicContact CG1-CD1 4.28Å; I120-I227 HydrophobicContact CG2-CG2 3.79Å; L121-I227 HydrophobicContact CD2-CB 4.18Å; L121-I227 HydrophobicContact CD2-CG2 3.64Å; L121-I227 HydrophobicContact CG-CG2 4.08Å; V124-I227 HydrophobicContact CG2-CD1 3.85Å; D223-I227 WeakPolarHBondContact O-CB 3.49Å; D223-I227 VanDerWaalsContact O-CG1 3.3Å; D223-I227 WeakPolarHBondContact O-CG1 3.48Å; D223-I227 PolarHBondContact O-N 3.2Å; D223-I227 WeakPolarHBondContact OD1-CD1 3.38Å; I227-F229 VanDerWaalsContact C-N 3.34Å; I227-F229 PolarHBondContact O-N 2.81Å; I227-L231 HydrophobicContact CG2-CB 3.96Å; I227-L231 HydrophobicContact CG2-CD2 3.78Å; I227-L231 VanDerWaalsContact O-CB 3.27Å; I227-L231 WeakPolarHBondContact O-CB 3.47Å; I227-L231 PolarHBondContact O-N 3.2Å
228F97.3Very high95.2Very high102 Ų10261.5 Ų61.545%0.44731%0.311SS..Hα-helixtrans-60-43.3-178.9-179.5-97.3000111.6R117 L121 L224 L225R117-F228 PolarHBondContact NH2-O 3.18Å; L121-F228 HydrophobicContact CD1-CD2 4.13Å; L121-F228 HydrophobicContact CD2-CB 4Å; L121-F228 HydrophobicContact CD2-CD2 4.5Å; L224-F228 WeakPolarHBondContact O-CB 3.42Å; L224-F228 PolarHBondContact O-N 3.31Å; L225-F228 PolarHBondContact O-N 3.39Å
229F97.3Very high94.5Very high147 Ų14760.5 Ų60.565%0.64530%0.303SS*.Hα-helixtrans-85.3-33.9-178.4-69.5-63.9000114.1L225 F226 I227L225-F229 HydrophobicContact CB-CD2 4.45Å; L225-F229 HydrophobicContact CB-CE2 4.43Å; L225-F229 HydrophobicContact CD2-CE2 4.16Å; L225-F229 WeakPolarHBondContact O-CD2 3.16Å; L225-F229 PolarHBondContact O-N 3.11Å; F226-F229 PolarHBondContact O-N 3.28Å; I227-F229 VanDerWaalsContact C-N 3.34Å; I227-F229 PolarHBondContact O-N 2.81Å
230L96.8Very high93.8Very high74 Ų7461.1 Ų61.139%0.38730%0.304SS..Hα-helixtrans-110.5-27.7-165.6-60.2174.9000114.8I27 F226 P232I27-L230 HydrophobicContact CD1-CB 4.49Å; I27-L230 VanDerWaalsContact CD1-O 3.3Å; I27-L230 WeakPolarHBondContact CD1-O 3.44Å; I27-L230 HydrophobicContact CG1-CB 4.47Å; I27-L230 HydrophobicContact CG2-CB 4.42Å; F226-L230 HydrophobicContact CD2-CD1 3.55Å; F226-L230 HydrophobicContact CE1-CD1 4.48Å; F226-L230 HydrophobicContact CE2-CD1 3.29Å; F226-L230 HydrophobicContact CG-CD1 4.24Å; F226-L230 HydrophobicContact CZ-CD1 3.8Å; F226-L230 VanDerWaalsContact O-CB 3.28Å; F226-L230 WeakPolarHBondContact O-CB 3.41Å; F226-L230 PolarHBondContact O-N 3.26Å; L230-P232 WeakPolarHBondContact O-CD 3.44Å
231L96.1Very high92.9Very high6 Ų663 Ų633%0.03132%0.315CS..  trans-76.2114.6-176.2-173.672000110.7I27 V28 R117 I120 I163 I227I27-L231 HydrophobicContact CG2-CB 4.14Å; I27-L231 HydrophobicContact CG2-CD1 3.83Å; V28-L231 HydrophobicContact CG2-CD1 4.14Å; R117-L231 VanDerWaalsContact CD-O 3.23Å; R117-L231 WeakPolarHBondContact CD-O 3.22Å; R117-L231 PolarHBondContact NE-O 2.69Å; I120-L231 HydrophobicContact CD1-CD2 4.43Å; I120-L231 HydrophobicContact CG2-CD2 3.67Å; I163-L231 HydrophobicContact CD1-CD1 4.4Å; I163-L231 HydrophobicContact CD1-CD2 3.92Å; I227-L231 HydrophobicContact CG2-CB 3.96Å; I227-L231 HydrophobicContact CG2-CD2 3.78Å; I227-L231 VanDerWaalsContact O-CB 3.27Å; I227-L231 WeakPolarHBondContact O-CB 3.47Å; I227-L231 PolarHBondContact O-N 3.2Å
232P94.2Very high91.3Very high55 Ų5566.2 Ų66.236%0.35734%0.34SS..  trans-73.1157.9172.632.7-35.4000110.9V24 L230 T234V24-P232 HydrophobicContact CG2-CG 3.84Å; L230-P232 WeakPolarHBondContact O-CD 3.44Å; P232-T234 PolarHBondContact O-N 3.27Å
233E94.8Very high89.5Confident60 Ų6066 Ų6628%0.2834%0.336SS..  trans-72.1125.1168.1-179.361-100.300109.8R116 R117 P118 L235 R240R116-E233 PolarHBondContact N-OE1 3.27Å; R116-E233 PolarHBondContact N-OE2 3.07Å; R117-E233 PolarHBondContact N-OE2 3.37Å; P118-E233 VanDerWaalsContact CD-OE2 3.31Å; P118-E233 WeakPolarHBondContact CD-OE2 3.38Å; E233-L235 WeakPolarHBondContact CG-O 3.49Å; E233-L235 PolarHBondContact OE1-N 3.47Å; E233-L235 VanDerWaalsContact OE1-N 3.14Å; E233-R240 IonicContact OE2-NH2 3.91Å; E233-R240 PolarHBondContact OE2-NH2 3.37Å
234T92.6Very high87.5Confident30 Ų3069.7 Ų69.718%0.18436%0.358CS..  trans-98.6-13.2179.356.40000113.5V24 R116 I163 D166 P232 P236V24-T234 HydrophobicContact CG1-CG2 4.19Å; R116-T234 VanDerWaalsContact CG-OG1 3.28Å; R116-T234 WeakPolarHBondContact CG-OG1 2.97Å; I163-T234 HydrophobicContact CG2-CG2 3.81Å; D166-T234 PolarHBondContact OD2-OG1 3Å; P232-T234 PolarHBondContact O-N 3.27Å; T234-P236 WeakPolarHBondContact O-CD 3.44Å
235L90.4Very high85Confident2 Ų274.2 Ų74.21%0.0139%0.388CS..SBendtrans-111.798.2174.9-171.965.5000111.4R116 E233 K239 R240R116-L235 HydrophobicContact CG-CB 4.21Å; E233-L235 WeakPolarHBondContact CG-O 3.49Å; E233-L235 PolarHBondContact OE1-N 3.47Å; E233-L235 VanDerWaalsContact OE1-N 3.14Å; L235-K239 HydrophobicContact CD1-CB 4.04Å; L235-R240 HydrophobicContact CD2-CG 3.95Å; L235-R240 HydrophobicContact CG-CG 3.99Å; L235-R240 PolarHBondContact O-NE 3.22Å; L235-R240 VanDerWaalsContact O-NE 3.08Å; L235-R240 PolarHBondContact O-NH2 3.22Å
236P87.9Confident82.6Confident57 Ų5773.8 Ų73.837%0.3739%0.392SS..  trans-58.7151.3176.8-22.432.8000112.4T234 E238 K239 R240T234-P236 WeakPolarHBondContact O-CD 3.44Å; P236-E238 WeakPolarHBondContact CB-OE2 3.17Å; P236-E238 PolarHBondContact O-N 3.5Å; P236-K239 PolarHBondContact O-N 2.88Å; P236-K239 VanDerWaalsContact O-N 3.09Å; P236-R240 WeakPolarHBondContact O-CG 3.27Å
237K86.7Confident80.3Confident159 Ų15973.4 Ų73.469%0.69140%0.4SS*.G310 helixtrans-59.5-32.8-174.7-72.7-176.9178.8-179.70112.8K239 R240K237-K239 VanDerWaalsContact C-N 3.25Å; K237-K239 PolarHBondContact O-N 3.44Å; K237-R240 WeakPolarHBondContact O-CB 3.49Å; K237-R240 PolarHBondContact O-N 3.38Å
238E85.2Confident78.2Confident161 Ų16181.6 Ų81.675%0.75244%0.436SS*.G310 helixtrans-70.7-23.7-177.2-51.970.7-148.200112P236P236-E238 WeakPolarHBondContact CB-OE2 3.17Å; P236-E238 PolarHBondContact O-N 3.5Å
239K82.8Confident76.4Confident102 Ų10281.9 Ų81.944%0.44344%0.439SS..G310 helixtrans-97.73179.3-62.9-173.8-179.9-179.70112.9L235 P236 K237 A399 S400L235-K239 HydrophobicContact CD1-CB 4.04Å; P236-K239 PolarHBondContact O-N 2.88Å; P236-K239 VanDerWaalsContact O-N 3.09Å; K237-K239 VanDerWaalsContact C-N 3.25Å; K237-K239 PolarHBondContact O-N 3.44Å; K239-A399 HydrophobicContact CD-CB 4.17Å; K239-S400 WeakPolarHBondContact O-CB 3.18Å
240R84.6Confident74.9Confident58 Ų5876.7 Ų76.722%0.21942%0.419CS..SBendtrans-81.8151.2-178.5-66.3174.6-165.5-165.4-9.1111.2C113 L114 E233 L235 P236 K237C113-R240 WeakPolarHBondContact O-CD 3.33Å; L114-R240 PolarHBondContact O-NH1 2.91Å; E233-R240 IonicContact OE2-NH2 3.91Å; E233-R240 PolarHBondContact OE2-NH2 3.37Å; L235-R240 HydrophobicContact CD2-CG 3.95Å; L235-R240 HydrophobicContact CG-CG 3.99Å; L235-R240 PolarHBondContact O-NE 3.22Å; L235-R240 VanDerWaalsContact O-NE 3.08Å; L235-R240 PolarHBondContact O-NH2 3.22Å; P236-R240 WeakPolarHBondContact O-CG 3.27Å; K237-R240 WeakPolarHBondContact O-CB 3.49Å; K237-R240 PolarHBondContact O-N 3.38Å
241V78.9Confident73.4Confident40 Ų4075 Ų7524%0.24242%0.416CS..  trans-71.6133.8172.4-172.90000108.9D112 S243D112-V241 HydrophobicContact CB-CG2 4.42Å; D112-V241 PolarHBondContact O-N 3.43Å; V241-S243 VanDerWaalsContact C-N 3.26Å; V241-S243 PolarHBondContact O-N 2.98Å
242S64.6Low72.1Confident128 Ų12877.4 Ų77.490%0.89543%0.431SS*.SBendtrans-69-15.3-172.752.90000115
243S61.1Low71.1Confident38 Ų3875.3 Ų75.327%0.26642%0.417SS..  trans-148.7140.117180.70000113.4V241 S246V241-S243 VanDerWaalsContact C-N 3.26Å; V241-S243 PolarHBondContact O-N 2.98Å; S243-S246 PolarHBondContact OG-N 2.85Å
244V55.5Low70.1Confident79 Ų7972.7 Ų72.748%0.47940%0.404SS..SBendtrans-72.9-23162.4179.90000110.2V110 C113V110-V244 HydrophobicContact CG2-CG1 4.4Å; C113-V244 HydrophobicContact CB-CB 4.47Å; C113-V244 HydrophobicContact CB-CG2 3.27Å; C113-V244 VanDerWaalsContact SG-CG2 3.57Å
245T45.8Very low69.5Low126 Ų12674.7 Ų74.777%0.77341%0.414SS*.  trans-100.17-158.327.60000115.9G247T245-G247 PolarHBondContact O-N 3.12Å
246S47Very low69.3Low80 Ų8076.7 Ų76.756%0.55943%0.428SS*.SBendtrans-75.970.4168.553.50000111.9S243 V250S243-S246 PolarHBondContact OG-N 2.85Å; S246-V250 VanDerWaalsContact O-CG2 3.25Å; S246-V250 WeakPolarHBondContact O-CG2 3.22Å
247G50.8Low69.1Low35 Ų3576.5 Ų76.536%0.36143%0.427SS..  trans113.2119.4153.800000115.4T245 Q249 V250 A251T245-G247 PolarHBondContact O-N 3.12Å; G247-Q249 PolarHBondContact O-N 2.92Å; G247-V250 PolarHBondContact O-N 3.35Å; G247-A251 PolarHBondContact O-N 2.95Å
248F52.9Low69.1Low175 Ų17575.5 Ų75.577%0.76843%0.428SS*.Hα-helixtrans-39.4-33.6150.7177.4-100.1000111.6V250 A251 V252F248-V250 PolarHBondContact O-N 3.32Å; F248-A251 WeakPolarHBondContact O-CB 3.22Å; F248-A251 PolarHBondContact O-N 3.42Å; F248-V252 HydrophobicContact CD1-CG2 3.94Å; F248-V252 HydrophobicContact CE1-CG2 3.72Å; F248-V252 HydrophobicContact CZ-CG2 4.13Å; F248-V252 VanDerWaalsContact O-CG2 3.28Å; F248-V252 WeakPolarHBondContact O-CG2 3.46Å; F248-V252 PolarHBondContact O-N 2.88Å
249Q59.3Low69.1Low107 Ų10768.4 Ų68.450%0.540%0.397SS..Hα-helixtrans-60.1-38.6173.2-160.563.647.600115.1G247 V252 D253G247-Q249 PolarHBondContact O-N 2.92Å; Q249-V252 PolarHBondContact O-N 3.37Å; Q249-D253 WeakPolarHBondContact O-CB 3.24Å; Q249-D253 PolarHBondContact O-N 3.09Å
250V66Low69.4Low39 Ų3963.6 Ų63.624%0.23638%0.376CS..Hα-helixtrans-71-37.6175.2174.60000110.2S246 G247 F248 D253 L254S246-V250 VanDerWaalsContact O-CG2 3.25Å; S246-V250 WeakPolarHBondContact O-CG2 3.22Å; G247-V250 PolarHBondContact O-N 3.35Å; F248-V250 PolarHBondContact O-N 3.32Å; V250-D253 PolarHBondContact O-N 3.35Å; V250-L254 HydrophobicContact CG1-CD1 3.93Å; V250-L254 HydrophobicContact CG1-CG 4.35Å; V250-L254 WeakPolarHBondContact O-CB 3.2Å; V250-L254 WeakPolarHBondContact O-CD1 3.48Å; V250-L254 WeakPolarHBondContact O-CG 3.3Å; V250-L254 PolarHBondContact O-N 2.96Å
251A64.6Low69.6Low38 Ų3863.1 Ų63.131%0.31438%0.375SS..Hα-helixtrans-62.6-43.1171.400000111.1G247 F248 L254 L255G247-A251 PolarHBondContact O-N 2.95Å; F248-A251 WeakPolarHBondContact O-CB 3.22Å; F248-A251 PolarHBondContact O-N 3.42Å; A251-L254 PolarHBondContact O-N 2.93Å; A251-L255 WeakPolarHBondContact O-CD1 3.43Å; A251-L255 WeakPolarHBondContact O-CG 3.42Å; A251-L255 PolarHBondContact O-N 3.34Å
252V67.6Low70Confident56 Ų5665.6 Ų65.634%0.33938%0.384SS..Hα-helixtrans-61.2-43.9173.9170.60000111.6F248 Q249 L254 L255 S256F248-V252 HydrophobicContact CD1-CG2 3.94Å; F248-V252 HydrophobicContact CE1-CG2 3.72Å; F248-V252 HydrophobicContact CZ-CG2 4.13Å; F248-V252 VanDerWaalsContact O-CG2 3.28Å; F248-V252 WeakPolarHBondContact O-CG2 3.46Å; F248-V252 PolarHBondContact O-N 2.88Å; Q249-V252 PolarHBondContact O-N 3.37Å; V252-L254 VanDerWaalsContact C-N 3.29Å; V252-L254 PolarHBondContact O-N 2.92Å; V252-L255 PolarHBondContact O-N 3.24Å; V252-S256 WeakPolarHBondContact O-CB 3.35Å; V252-S256 PolarHBondContact O-N 2.92Å
253D73.1Confident71.1Confident12 Ų1259.5 Ų59.56%0.06434%0.342CS..Hα-helixtrans-63.5-34.5176-70.6-16.6000112.1Q249 V250 L255 A259 R268Q249-D253 WeakPolarHBondContact O-CB 3.24Å; Q249-D253 PolarHBondContact O-N 3.09Å; V250-D253 PolarHBondContact O-N 3.35Å; D253-L255 VanDerWaalsContact C-N 3.3Å; D253-A259 HydrophobicContact CB-CB 4.18Å; D253-A259 WeakPolarHBondContact O-CB 3.35Å; D253-R268 VanDerWaalsContact CG-NH1 3.32Å; D253-R268 IonicContact OD1-NH1 3.65Å; D253-R268 PolarHBondContact OD1-NH1 2.98Å; D253-R268 IonicContact OD2-CZ 3.56Å; D253-R268 IonicContact OD2-NE 2.71Å; D253-R268 IonicContact OD2-NH1 3.83Å; D253-R268 PolarHBondContact OD2-NH1 3.35Å
254L74.4Confident72Confident5 Ų558.6 Ų58.63%0.02634%0.335CS..Hα-helixtrans-76.6-16.7177.9-72.8171000113P105 A109 V250 A251 V252 A265 I408P105-L254 HydrophobicContact CB-CB 3.99Å; P105-L254 HydrophobicContact CB-CD2 3.62Å; P105-L254 HydrophobicContact CB-CG 4.31Å; A109-L254 HydrophobicContact CB-CD1 3.75Å; V250-L254 HydrophobicContact CG1-CD1 3.93Å; V250-L254 HydrophobicContact CG1-CG 4.35Å; V250-L254 WeakPolarHBondContact O-CB 3.2Å; V250-L254 WeakPolarHBondContact O-CD1 3.48Å; V250-L254 WeakPolarHBondContact O-CG 3.3Å; V250-L254 PolarHBondContact O-N 2.96Å; A251-L254 PolarHBondContact O-N 2.93Å; V252-L254 VanDerWaalsContact C-N 3.29Å; V252-L254 PolarHBondContact O-N 2.92Å; L254-A265 HydrophobicContact CD2-CB 3.59Å; L254-A265 HydrophobicContact CG-CB 4.05Å; L254-I408 HydrophobicContact CD2-CG1 4.44Å
255L80.1Confident73Confident72 Ų7255.1 Ų55.138%0.37732%0.315SS..Hα-helixtrans-102.3-21.7178.6-63.3169.2000112.5F102 A251 V252 D253 P257F102-L255 HydrophobicContact CB-CD2 3.89Å; F102-L255 HydrophobicContact CD1-CB 4.33Å; F102-L255 HydrophobicContact CD1-CD2 3.51Å; F102-L255 HydrophobicContact CD1-CG 4.49Å; F102-L255 HydrophobicContact CE1-CD2 4.45Å; F102-L255 HydrophobicContact CG-CD2 4.13Å; A251-L255 WeakPolarHBondContact O-CD1 3.43Å; A251-L255 WeakPolarHBondContact O-CG 3.42Å; A251-L255 PolarHBondContact O-N 3.34Å; V252-L255 PolarHBondContact O-N 3.24Å; D253-L255 VanDerWaalsContact C-N 3.3Å; L255-P257 WeakPolarHBondContact O-CD 3.17Å
256S86.8Confident74.7Confident44 Ų4449.1 Ų49.131%0.30828%0.278SS..  trans-79121.8-179.5172.50000111.8V252 L258 A259 L260V252-S256 WeakPolarHBondContact O-CB 3.35Å; V252-S256 PolarHBondContact O-N 2.92Å; S256-L258 VanDerWaalsContact C-N 3.3Å; S256-L258 PolarHBondContact O-N 3.06Å; S256-A259 PolarHBondContact O-N 3.36Å; S256-A259 VanDerWaalsContact O-N 3.13Å; S256-L260 WeakPolarHBondContact O-CG 3.43Å; S256-L260 PolarHBondContact O-N 3.38Å
257P83.3Confident75.8Confident53 Ų5347 Ų4734%0.34426%0.263SS..Hα-helixtrans-53.9-44.3177.9-24.631.2000113.1F101 L255 A259 L260 F261 L415F101-P257 HydrophobicContact CE1-CG 4.41Å; F101-P257 HydrophobicContact CZ-CB 4.28Å; F101-P257 HydrophobicContact CZ-CG 3.81Å; L255-P257 WeakPolarHBondContact O-CD 3.17Å; P257-A259 VanDerWaalsContact C-N 3.34Å; P257-A259 PolarHBondContact O-N 3.24Å; P257-L260 WeakPolarHBondContact O-CB 3.42Å; P257-L260 PolarHBondContact O-N 2.99Å; P257-F261 WeakPolarHBondContact O-CD2 3.41Å; P257-F261 PolarHBondContact O-N 3.42Å; P257-F261 VanDerWaalsContact O-N 3.13Å; P257-L415 HydrophobicContact CB-CD2 4.26Å
258L86.8Confident76.6Confident138 Ų13853 Ų5372%0.72328%0.275SS*.Hα-helixtrans-63.5-40.9-179.6-8478.6000111.6S256 L260 F261 Q262S256-L258 VanDerWaalsContact C-N 3.3Å; S256-L258 PolarHBondContact O-N 3.06Å; L258-L260 VanDerWaalsContact C-N 3.31Å; L258-L260 PolarHBondContact O-N 3.08Å; L258-F261 PolarHBondContact O-N 3.28Å; L258-Q262 WeakPolarHBondContact O-CG 3.25Å; L258-Q262 PolarHBondContact O-N 3.15Å; L258-Q262 VanDerWaalsContact O-N 3.13Å
259A85.5Confident77.1Confident11 Ų1145.7 Ų45.79%0.09125%0.249CC..Hα-helixtrans-68.3-31.9179.200000112.2D253 S256 P257 Q262 F263 S264D253-A259 HydrophobicContact CB-CB 4.18Å; D253-A259 WeakPolarHBondContact O-CB 3.35Å; S256-A259 PolarHBondContact O-N 3.36Å; S256-A259 VanDerWaalsContact O-N 3.13Å; P257-A259 VanDerWaalsContact C-N 3.34Å; P257-A259 PolarHBondContact O-N 3.24Å; A259-Q262 CarbonylContact O-C 3.59Å; A259-Q262 PolarHBondContact O-N 3.25Å; A259-F263 PolarHBondContact O-N 3.07Å; A259-S264 PolarHBondContact O-N 3.34Å; A259-S264 PolarHBondContact O-OG 3.2Å
260L87.9Confident77.2Confident1 Ų152.9 Ų52.91%0.00527%0.271CS..Hα-helixtrans-66.4-43.7173.5-66.2171.9000112F101 P105 S256 P257 L258 Q262 F263 I408 S411 L412F101-L260 HydrophobicContact CD2-CD1 4.2Å; F101-L260 HydrophobicContact CE2-CD1 3.28Å; F101-L260 HydrophobicContact CZ-CD1 3.62Å; P105-L260 HydrophobicContact CB-CD2 4.27Å; P105-L260 HydrophobicContact CG-CD2 4Å; S256-L260 WeakPolarHBondContact O-CG 3.43Å; S256-L260 PolarHBondContact O-N 3.38Å; P257-L260 WeakPolarHBondContact O-CB 3.42Å; P257-L260 PolarHBondContact O-N 2.99Å; L258-L260 VanDerWaalsContact C-N 3.31Å; L258-L260 PolarHBondContact O-N 3.08Å; L260-Q262 PolarHBondContact O-N 2.9Å; L260-F263 PolarHBondContact O-N 3.21Å; L260-F263 VanDerWaalsContact O-N 3.08Å; L260-I408 HydrophobicContact CB-CG2 4.17Å; L260-I408 HydrophobicContact CD2-CB 4.24Å; L260-I408 HydrophobicContact CD2-CG1 3.73Å; L260-I408 HydrophobicContact CD2-CG2 3.99Å; L260-I408 WeakPolarHBondContact O-CG2 3.35Å; L260-S411 WeakPolarHBondContact CD1-OG 3.49Å; L260-L412 HydrophobicContact CB-CD2 4.02Å
261F90.1Very high77.4Confident48 Ų4855.6 Ų55.621%0.21129%0.285CS..Hα-helixtrans-63.7-29.4174-78.8-73.5000113P257 L258 F263 L286 F289 L412 L415P257-F261 WeakPolarHBondContact O-CD2 3.41Å; P257-F261 PolarHBondContact O-N 3.42Å; P257-F261 VanDerWaalsContact O-N 3.13Å; L258-F261 PolarHBondContact O-N 3.28Å; F261-F263 VanDerWaalsContact C-N 3.34Å; F261-L286 HydrophobicContact CD1-CD1 4.1Å; F261-L286 HydrophobicContact CE1-CD1 3.82Å; F261-F289 HydrophobicContact CE1-CB 3.73Å; F261-F289 AromaticContact CE1-CD1 3.93Å; F261-F289 HydrophobicContact CE1-CD1 3.93Å; F261-F289 HydrophobicContact CE1-CD2 4.21Å; F261-F289 AromaticContact CE1-CG 3.68Å; F261-F289 HydrophobicContact CE1-CG 3.68Å; F261-F289 HydrophobicContact CZ-CB 4.07Å; F261-F289 AromaticContact CZ-CD1 3.7Å; F261-F289 HydrophobicContact CZ-CD1 3.7Å; F261-F289 AromaticContact CZ-CD2 3.65Å; F261-F289 HydrophobicContact CZ-CD2 3.65Å; F261-F289 HydrophobicContact CZ-CE1 4.04Å; F261-F289 AromaticContact CZ-CE2 4Å; F261-F289 HydrophobicContact CZ-CE2 4Å; F261-F289 AromaticContact CZ-CG 3.51Å; F261-F289 HydrophobicContact CZ-CG 3.51Å; F261-F289 HydrophobicContact CZ-CZ 4.18Å; F261-L412 HydrophobicContact CD1-CD1 4.49Å; F261-L412 HydrophobicContact CD1-CD2 3.91Å; F261-L412 HydrophobicContact CD2-CD2 4.07Å; F261-L412 HydrophobicContact CE1-CD2 3.81Å; F261-L412 HydrophobicContact CE2-CD2 3.94Å; F261-L412 HydrophobicContact CG-CD2 4.04Å; F261-L412 HydrophobicContact CZ-CD2 3.82Å; F261-L415 HydrophobicContact CE2-CD2 4.48Å
262Q87.6Confident77.7Confident93 Ų9356.5 Ų56.544%0.43529%0.289SS..THydrogen-bonded Turntrans-84.8-7.3176-65.2-64.4-24.500113.3L258 A259 L260 S264 K282L258-Q262 WeakPolarHBondContact O-CG 3.25Å; L258-Q262 PolarHBondContact O-N 3.15Å; L258-Q262 VanDerWaalsContact O-N 3.13Å; A259-Q262 CarbonylContact O-C 3.59Å; A259-Q262 PolarHBondContact O-N 3.25Å; L260-Q262 PolarHBondContact O-N 2.9Å; Q262-S264 WeakPolarHBondContact CB-OG 3.5Å; Q262-S264 PolarHBondContact O-N 3.41Å; Q262-K282 WeakPolarHBondContact O-CE 3.44Å
263F86Confident78.1Confident0 Ų054.7 Ų54.70%028%0.278CS..THydrogen-bonded Turntrans50.436.8-171.1-70.5-100.4000112.7A259 L260 F261 A265 V266 S267 L278 L281 K282 I408 L412A259-F263 PolarHBondContact O-N 3.07Å; L260-F263 PolarHBondContact O-N 3.21Å; L260-F263 VanDerWaalsContact O-N 3.08Å; F261-F263 VanDerWaalsContact C-N 3.34Å; F263-A265 VanDerWaalsContact C-N 3.25Å; F263-A265 PolarHBondContact O-N 3.46Å; F263-V266 HydrophobicContact CD1-CG2 4.46Å; F263-V266 WeakPolarHBondContact O-CB 3.45Å; F263-V266 PolarHBondContact O-N 3.06Å; F263-S267 PolarHBondContact O-N 3.3Å; F263-S267 VanDerWaalsContact O-N 3.09Å; F263-L278 HydrophobicContact CB-CD1 4.22Å; F263-L281 HydrophobicContact CB-CD2 4.02Å; F263-L281 HydrophobicContact CD1-CD1 4.32Å; F263-L281 HydrophobicContact CD1-CD2 3.44Å; F263-L281 VanDerWaalsContact CD1-CD2 3.44Å; F263-L281 HydrophobicContact CD1-CG 3.67Å; F263-L281 HydrophobicContact CD2-CD2 4.34Å; F263-L281 HydrophobicContact CD2-CG 3.96Å; F263-L281 HydrophobicContact CE1-CD1 3.92Å; F263-L281 HydrophobicContact CE1-CD2 3.91Å; F263-L281 HydrophobicContact CE1-CG 3.71Å; F263-L281 HydrophobicContact CE2-CG 4Å; F263-L281 VanDerWaalsContact CE2-O 3.3Å; F263-L281 WeakPolarHBondContact CE2-O 3.34Å; F263-L281 HydrophobicContact CG-CD2 3.68Å; F263-L281 HydrophobicContact CG-CG 3.8Å; F263-L281 HydrophobicContact CZ-CD1 4.1Å; F263-L281 HydrophobicContact CZ-CG 3.88Å; F263-K282 HydrophobicContact CD2-CG 4.35Å; F263-I408 HydrophobicContact CD1-CB 4.09Å; F263-I408 HydrophobicContact CD1-CD1 3.86Å; F263-I408 HydrophobicContact CD1-CG2 3.66Å; F263-I408 HydrophobicContact CE1-CB 3.89Å; F263-I408 HydrophobicContact CE1-CG2 3.43Å; F263-I408 VanDerWaalsContact CE1-CG2 3.43Å; F263-I408 HydrophobicContact CE2-CG2 4.4Å; F263-I408 HydrophobicContact CG-CG2 4.25Å; F263-I408 HydrophobicContact CZ-CG2 3.84Å; F263-L412 HydrophobicContact CE2-CD1 4.31Å; F263-L412 HydrophobicContact CZ-CD1 4.21Å
264S80.8Confident78.5Confident19 Ų1957.1 Ų57.113%0.13330%0.296CS..Hα-helixtrans-58.5-34.8-172.4-60.90000113.4A259 Q262 V266 S267 R268A259-S264 PolarHBondContact O-N 3.34Å; A259-S264 PolarHBondContact O-OG 3.2Å; Q262-S264 WeakPolarHBondContact CB-OG 3.5Å; Q262-S264 PolarHBondContact O-N 3.41Å; S264-V266 PolarHBondContact O-N 3.4Å; S264-S267 WeakPolarHBondContact CA-OG 3.38Å; S264-S267 PolarHBondContact O-N 2.81Å; S264-S267 PolarHBondContact O-OG 3.44Å; S264-S267 VanDerWaalsContact O-OG 3.12Å; S264-R268 WeakPolarHBondContact O-CG 3.31Å; S264-R268 PolarHBondContact O-N 2.96Å
265A77.7Confident78.9Confident5 Ų565 Ų654%0.04133%0.333CS..Hα-helixtrans-68.8-15.817800000113.9L254 F263 R404 I408L254-A265 HydrophobicContact CD2-CB 3.59Å; L254-A265 HydrophobicContact CG-CB 4.05Å; F263-A265 VanDerWaalsContact C-N 3.25Å; F263-A265 PolarHBondContact O-N 3.46Å; A265-R404 PolarHBondContact O-NH1 2.95Å; A265-I408 HydrophobicContact CB-CD1 4.41Å
266V80Confident79.1Confident0 Ų066 Ų660%033%0.334CS..Hα-helixtrans-95-39.5173.7-175.70000110.2F263 S264 R268 G269 P273 R404 V405 I408F263-V266 HydrophobicContact CD1-CG2 4.46Å; F263-V266 WeakPolarHBondContact O-CB 3.45Å; F263-V266 PolarHBondContact O-N 3.06Å; S264-V266 PolarHBondContact O-N 3.4Å; V266-R268 VanDerWaalsContact C-N 3.29Å; V266-R268 PolarHBondContact O-N 3.24Å; V266-G269 PolarHBondContact O-N 2.96Å; V266-P273 HydrophobicContact CG1-CG 3.88Å; V266-R404 HydrophobicContact CG2-CB 4.26Å; V266-V405 HydrophobicContact CG1-CG2 4.07Å; V266-V405 HydrophobicContact CG2-CG2 3.82Å; V266-I408 HydrophobicContact CG2-CD1 3.8Å
267S71.3Confident79.1Confident35 Ų3565.5 Ų65.525%0.24533%0.328CS..Hα-helixtrans-71.4-19.5-176.369.10000114.7F263 S264 S272F263-S267 PolarHBondContact O-N 3.3Å; F263-S267 VanDerWaalsContact O-N 3.09Å; S264-S267 WeakPolarHBondContact CA-OG 3.38Å; S264-S267 PolarHBondContact O-N 2.81Å; S264-S267 PolarHBondContact O-OG 3.44Å; S264-S267 VanDerWaalsContact O-OG 3.12Å; S267-S272 WeakPolarHBondContact CA-OG 3.46Å; S267-S272 WeakPolarHBondContact O-CB 3.37Å; S267-S272 PolarHBondContact O-OG 3.18Å
268R66.9Low79.3Confident162 Ų16264 Ų6461%0.61132%0.317SS*.THydrogen-bonded Turntrans-92.3-1.3-178.3-68.7176.8176.4-179.5-3.9114.2D253 S264 V266D253-R268 VanDerWaalsContact CG-NH1 3.32Å; D253-R268 IonicContact OD1-NH1 3.65Å; D253-R268 PolarHBondContact OD1-NH1 2.98Å; D253-R268 IonicContact OD2-CZ 3.56Å; D253-R268 IonicContact OD2-NE 2.71Å; D253-R268 IonicContact OD2-NH1 3.83Å; D253-R268 PolarHBondContact OD2-NH1 3.35Å; S264-R268 WeakPolarHBondContact O-CG 3.31Å; S264-R268 PolarHBondContact O-N 2.96Å; V266-R268 VanDerWaalsContact C-N 3.29Å; V266-R268 PolarHBondContact O-N 3.24Å
269G64.3Low79.4Confident22 Ų2262.9 Ų62.923%0.22731%0.308CS..SBendtrans-76.9160.1177.300000113V266 D271 S272V266-G269 PolarHBondContact O-N 2.96Å; G269-D271 PolarHBondContact O-N 3.47Å; G269-S272 PolarHBondContact O-N 3.39Å
270R61.1Low79.8Confident257 Ų25762.5 Ų62.597%0.9730%0.304SS*.SBendtrans-57.6-34.7173.2-75.6-175.7179.3175.8-1112.4S272R270-S272 PolarHBondContact O-N 2.95Å
271D68.7Low80Confident97 Ų9762.4 Ų62.452%0.51930%0.304SS..SBendtrans-97.158.1175.6-52.6-41.5000110.7G269 A398 Q401G269-D271 PolarHBondContact O-N 3.47Å; D271-A398 HydrophobicContact CB-CB 3.78Å; D271-Q401 PolarHBondContact O-NE2 3.08Å; D271-Q401 PolarHBondContact O-OE1 3.1Å
272S71.8Confident80.2Confident56 Ų5663.2 Ų63.239%0.39231%0.307SS..PPolyproline II helixtrans-70.1136.6-179.1-165.30000110.7S267 G269 R270S267-S272 WeakPolarHBondContact CA-OG 3.46Å; S267-S272 WeakPolarHBondContact O-CB 3.37Å; S267-S272 PolarHBondContact O-OG 3.18Å; G269-S272 PolarHBondContact O-N 3.39Å; R270-S272 PolarHBondContact O-N 2.95Å
273P77.1Confident80.5Confident19 Ų1960.1 Ų60.112%0.12329%0.293CS..PPolyproline II helixtrans-58.3148.7172.7-19.230000111.2V266 N277 L278V266-P273 HydrophobicContact CG1-CG 3.88Å; P273-N277 HydrophobicContact CB-CB 4.06Å; P273-L278 HydrophobicContact CB-CB 4.49Å
274S80.3Confident81Confident62 Ų6260.1 Ų60.143%0.43429%0.293SS..PPolyproline II helixtrans-53.4150.417067.40000111.1K276 N277 L278S274-K276 PolarHBondContact O-N 3.33Å; S274-K276 VanDerWaalsContact O-N 3.14Å; S274-N277 CarbonylContact O-C 3.57Å; S274-N277 WeakPolarHBondContact O-CA 3.48Å; S274-N277 WeakPolarHBondContact O-CB 3.34Å; S274-N277 PolarHBondContact O-N 3.01Å; S274-N277 WeakPolarHBondContact OG-CB 3.48Å; S274-N277 PolarHBondContact OG-N 3.17Å; S274-N277 PolarHBondContact OG-ND2 2.98Å; S274-L278 PolarHBondContact O-N 2.92Å
275E82.4Confident81.7Confident171 Ų17159.2 Ų59.280%0.79929%0.287SS*.Hα-helixtrans-53.5-40.4-175.4-171.3176.8-174.500112.4L278 Q279E275-L278 PolarHBondContact O-N 2.95Å; E275-Q279 WeakPolarHBondContact O-CB 3.44Å; E275-Q279 PolarHBondContact O-N 3.24Å
276K84.4Confident82.6Confident92 Ų9262 Ų6240%0.430%0.301SS..Hα-helixtrans-62.3-44.3174-175.9-177.7174.9-171.90112.5S274 Q279 N280S274-K276 PolarHBondContact O-N 3.33Å; S274-K276 VanDerWaalsContact O-N 3.14Å; K276-Q279 PolarHBondContact O-N 3.02Å; K276-N280 PolarHBondContact O-N 3.04Å
277N86.5Confident83.5Confident34 Ų3462 Ų6218%0.18230%0.301CS..Hα-helixtrans-67.8-37.7178.3-79.9-21.2000111.6P273 S274 N280 L281 Y396 Q457P273-N277 HydrophobicContact CB-CB 4.06Å; S274-N277 CarbonylContact O-C 3.57Å; S274-N277 WeakPolarHBondContact O-CA 3.48Å; S274-N277 WeakPolarHBondContact O-CB 3.34Å; S274-N277 PolarHBondContact O-N 3.01Å; S274-N277 WeakPolarHBondContact OG-CB 3.48Å; S274-N277 PolarHBondContact OG-N 3.17Å; S274-N277 PolarHBondContact OG-ND2 2.98Å; N277-N280 PolarHBondContact O-N 3.41Å; N277-L281 WeakPolarHBondContact O-CB 3.24Å; N277-L281 PolarHBondContact O-N 3.46Å; N277-Y396 HydrophobicContact CB-CD1 3.92Å; N277-Y396 HydrophobicContact CB-CE1 3.94Å; N277-Q457 PolarHBondContact OD1-NE2 3.15Å; N277-Q457 VanDerWaalsContact OD1-NE2 3.16Å
278L88.1Confident84.7Confident23 Ų2360.9 Ų60.912%0.1229%0.292CS..Hα-helixtrans-65.7-42.7174.5-176.863000111.4F263 P273 S274 E275 L281 K282F263-L278 HydrophobicContact CB-CD1 4.22Å; P273-L278 HydrophobicContact CB-CB 4.49Å; S274-L278 PolarHBondContact O-N 2.92Å; E275-L278 PolarHBondContact O-N 2.95Å; L278-L281 WeakPolarHBondContact O-CB 3.33Å; L278-L281 PolarHBondContact O-N 3.36Å; L278-K282 WeakPolarHBondContact O-CG 3.37Å; L278-K282 PolarHBondContact O-N 3.03Å
279Q90.1Very high86.2Confident113 Ų11354.6 Ų54.653%0.52827%0.269SS..Hα-helixtrans-61.8-44.8175.2-170.4178.425.600111.7E275 K276 L281 K282 I283E275-Q279 WeakPolarHBondContact O-CB 3.44Å; E275-Q279 PolarHBondContact O-N 3.24Å; K276-Q279 PolarHBondContact O-N 3.02Å; Q279-L281 VanDerWaalsContact C-N 3.3Å; Q279-L281 PolarHBondContact O-N 3.03Å; Q279-K282 PolarHBondContact O-N 2.87Å; Q279-I283 HydrophobicContact CG-CD1 4.18Å; Q279-I283 WeakPolarHBondContact O-CG1 3.23Å; Q279-I283 PolarHBondContact O-N 3.44Å
280N92.1Very high87.8Confident3 Ų354.9 Ų54.92%0.01627%0.265CS..Hα-helixtrans-57.9-43.4173.7-80.7-17.5000111.5K276 N277 I283 L284 Y396 V454 K455K276-N280 PolarHBondContact O-N 3.04Å; N277-N280 PolarHBondContact O-N 3.41Å; N280-I283 PolarHBondContact O-N 2.84Å; N280-L284 WeakPolarHBondContact O-CB 3.35Å; N280-L284 WeakPolarHBondContact O-CG 3.44Å; N280-L284 PolarHBondContact O-N 2.87Å; N280-Y396 HydrophobicContact CB-CE1 4.07Å; N280-V454 HydrophobicContact CB-CG1 4.47Å; N280-K455 PolarHBondContact ND2-O 2.81Å; N280-K455 PolarHBondContact OD1-N 2.95Å
281L92.1Very high89.5Confident0 Ų042.7 Ų42.70%022%0.219CC..Hα-helixtrans-62.8-42.6178.7-171.362.6000112.2F263 N277 L278 Q279 L284 G285 V393 Y396 V405F263-L281 HydrophobicContact CB-CD2 4.02Å; F263-L281 HydrophobicContact CD1-CD1 4.32Å; F263-L281 HydrophobicContact CD1-CD2 3.44Å; F263-L281 VanDerWaalsContact CD1-CD2 3.44Å; F263-L281 HydrophobicContact CD1-CG 3.67Å; F263-L281 HydrophobicContact CD2-CD2 4.34Å; F263-L281 HydrophobicContact CD2-CG 3.96Å; F263-L281 HydrophobicContact CE1-CD1 3.92Å; F263-L281 HydrophobicContact CE1-CD2 3.91Å; F263-L281 HydrophobicContact CE1-CG 3.71Å; F263-L281 HydrophobicContact CE2-CG 4Å; F263-L281 VanDerWaalsContact CE2-O 3.3Å; F263-L281 WeakPolarHBondContact CE2-O 3.34Å; F263-L281 HydrophobicContact CG-CD2 3.68Å; F263-L281 HydrophobicContact CG-CG 3.8Å; F263-L281 HydrophobicContact CZ-CD1 4.1Å; F263-L281 HydrophobicContact CZ-CG 3.88Å; N277-L281 WeakPolarHBondContact O-CB 3.24Å; N277-L281 PolarHBondContact O-N 3.46Å; L278-L281 WeakPolarHBondContact O-CB 3.33Å; L278-L281 PolarHBondContact O-N 3.36Å; Q279-L281 VanDerWaalsContact C-N 3.3Å; Q279-L281 PolarHBondContact O-N 3.03Å; L281-L284 PolarHBondContact O-N 2.87Å; L281-G285 PolarHBondContact O-N 3.44Å; L281-V393 HydrophobicContact CD1-CG1 3.79Å; L281-V393 HydrophobicContact CD1-CG2 4.4Å; L281-Y396 HydrophobicContact CD1-CD2 4.31Å; L281-Y396 HydrophobicContact CD1-CG 4.26Å; L281-V405 HydrophobicContact CD1-CG1 4.28Å
282K94.6Very high90.9Very high65 Ų6538 Ų3828%0.28319%0.194SC..Hα-helixtrans-60.3-46.1174.3-68174.8-177.6-175.60111.8Q262 F263 L278 Q279 G285 L286Q262-K282 WeakPolarHBondContact O-CE 3.44Å; F263-K282 HydrophobicContact CD2-CG 4.35Å; L278-K282 WeakPolarHBondContact O-CG 3.37Å; L278-K282 PolarHBondContact O-N 3.03Å; Q279-K282 PolarHBondContact O-N 2.87Å; K282-G285 PolarHBondContact O-N 3.06Å; K282-L286 WeakPolarHBondContact O-CB 3.27Å; K282-L286 PolarHBondContact O-N 3.43Å
283I94.9Very high92.2Very high27 Ų2736.9 Ų36.914%0.13818%0.182CC..Hα-helixtrans-62.5-45.2177.6-66.8167.1000110.7Q279 N280 L286 A287 L450 V454Q279-I283 HydrophobicContact CG-CD1 4.18Å; Q279-I283 WeakPolarHBondContact O-CG1 3.23Å; Q279-I283 PolarHBondContact O-N 3.44Å; N280-I283 PolarHBondContact O-N 2.84Å; I283-L286 PolarHBondContact O-N 2.88Å; I283-A287 WeakPolarHBondContact O-CB 3.41Å; I283-A287 PolarHBondContact O-N 3.41Å; I283-L450 HydrophobicContact CG2-CB 4.26Å; I283-L450 VanDerWaalsContact CG2-O 3.22Å; I283-L450 WeakPolarHBondContact CG2-O 3.29Å; I283-V454 HydrophobicContact CB-CG2 4.31Å; I283-V454 HydrophobicContact CG2-CG2 3.62Å
284L95.8Very high93.1Very high0 Ų036.2 Ų36.20%018%0.178CC..Hα-helixtrans-63.3-43.3178-71.4166.4000111.9N280 L281 A287 Y288 I345 L389 V392 V393 Y396 L451 V454N280-L284 WeakPolarHBondContact O-CB 3.35Å; N280-L284 WeakPolarHBondContact O-CG 3.44Å; N280-L284 PolarHBondContact O-N 2.87Å; L281-L284 PolarHBondContact O-N 2.87Å; L284-A287 PolarHBondContact O-N 3.42Å; L284-Y288 VanDerWaalsContact O-CB 3.22Å; L284-Y288 WeakPolarHBondContact O-CB 3.22Å; L284-Y288 PolarHBondContact O-N 3.33Å; L284-I345 HydrophobicContact CD2-CD1 3.68Å; L284-L389 HydrophobicContact CD2-CD2 4.07Å; L284-V392 HydrophobicContact CD1-CG1 3.73Å; L284-V392 HydrophobicContact CD2-CG1 4.27Å; L284-V393 HydrophobicContact CB-CG2 3.84Å; L284-V393 HydrophobicContact CD1-CG2 4.08Å; L284-V393 HydrophobicContact CG-CG2 4.5Å; L284-Y396 HydrophobicContact CD1-CD2 4.38Å; L284-Y396 HydrophobicContact CD1-CE2 3.63Å; L284-L451 HydrophobicContact CD2-CD2 3.82Å; L284-V454 HydrophobicContact CD2-CG2 4.24Å; L284-V454 HydrophobicContact CG-CG2 4.38Å
285G95.9Very high93.9Very high0 Ų033.7 Ų33.70%016%0.159CC..Hα-helixtrans-63.6-42.9176.400000112.6L281 K282 Y288 F289L281-G285 PolarHBondContact O-N 3.44Å; K282-G285 PolarHBondContact O-N 3.06Å; G285-Y288 PolarHBondContact O-N 2.83Å; G285-F289 WeakPolarHBondContact O-CB 3.49Å; G285-F289 PolarHBondContact O-N 3.22Å
286L97.1Very high94.6Very high64 Ų6425.8 Ų25.834%0.33512%0.123SC..Hα-helixtrans-64.7-45.4175.3-178.262000111.8F261 K282 I283 Y288 F289 I290 L450F261-L286 HydrophobicContact CD1-CD1 4.1Å; F261-L286 HydrophobicContact CE1-CD1 3.82Å; K282-L286 WeakPolarHBondContact O-CB 3.27Å; K282-L286 PolarHBondContact O-N 3.43Å; I283-L286 PolarHBondContact O-N 2.88Å; L286-Y288 VanDerWaalsContact C-N 3.31Å; L286-Y288 PolarHBondContact O-N 2.67Å; L286-F289 PolarHBondContact O-N 3.02Å; L286-I290 HydrophobicContact CD1-CD1 3.93Å; L286-I290 HydrophobicContact CD1-CG1 4.19Å; L286-I290 HydrophobicContact CG-CD1 3.91Å; L286-I290 WeakPolarHBondContact O-CG1 3.25Å; L286-I290 PolarHBondContact O-N 3.4Å; L286-L450 HydrophobicContact CD2-CD1 3.85Å; L286-L450 HydrophobicContact CD2-CD2 4.38Å; L286-L450 HydrophobicContact CG-CD1 3.92Å
287A97.3Very high95.1Very high1 Ų121.4 Ų21.41%0.00810%0.104CC..Hα-helixtrans-61.8-40.7176.200000111.6I283 L284 Y291 P447 L450 L451I283-A287 WeakPolarHBondContact O-CB 3.41Å; I283-A287 PolarHBondContact O-N 3.41Å; L284-A287 PolarHBondContact O-N 3.42Å; A287-Y291 WeakPolarHBondContact O-CB 3.22Å; A287-Y291 PolarHBondContact O-N 3.07Å; A287-P447 HydrophobicContact CB-CB 4.16Å; A287-L450 HydrophobicContact CB-CB 4.45Å; A287-L451 HydrophobicContact CB-CD2 3.87Å; A287-L451 HydrophobicContact CB-CG 3.97Å
288Y97.4Very high95.6Very high10 Ų1019.8 Ų19.84%0.03910%0.095CC..Hα-helixtrans-63-44.2175.6-174.7-95.9000112.2L284 G285 L286 L292 I386 L389 L409L284-Y288 VanDerWaalsContact O-CB 3.22Å; L284-Y288 WeakPolarHBondContact O-CB 3.22Å; L284-Y288 PolarHBondContact O-N 3.33Å; G285-Y288 PolarHBondContact O-N 2.83Å; L286-Y288 VanDerWaalsContact C-N 3.31Å; L286-Y288 PolarHBondContact O-N 2.67Å; Y288-L292 HydrophobicContact CD1-CD1 3.94Å; Y288-L292 HydrophobicContact CE1-CD1 3.31Å; Y288-L292 HydrophobicContact CE1-CG 4.44Å; Y288-L292 HydrophobicContact CE2-CD1 4.23Å; Y288-L292 VanDerWaalsContact CZ-CD1 3.48Å; Y288-L292 WeakPolarHBondContact O-CB 3.48Å; Y288-L292 PolarHBondContact O-N 2.91Å; Y288-I386 HydrophobicContact CE2-CG2 4.21Å; Y288-L389 HydrophobicContact CD2-CB 3.99Å; Y288-L389 HydrophobicContact CD2-CD1 3.89Å; Y288-L409 HydrophobicContact CD1-CD1 3.59Å; Y288-L409 HydrophobicContact CD1-CG 3.95Å; Y288-L409 HydrophobicContact CD2-CD1 4.05Å; Y288-L409 HydrophobicContact CD2-CG 4.4Å; Y288-L409 HydrophobicContact CE1-CD1 4.09Å; Y288-L409 HydrophobicContact CE1-CG 3.91Å; Y288-L409 WeakPolarHBondContact CE1-O 3.48Å; Y288-L409 HydrophobicContact CE2-CD2 4.41Å; Y288-L409 HydrophobicContact CE2-CG 4.39Å; Y288-L409 HydrophobicContact CG-CD1 3.57Å; Y288-L409 HydrophobicContact CG-CG 4.2Å
289F98Very high95.9Very high30 Ų3021.7 Ų21.713%0.13210%0.103CC..Hα-helixtrans-60.1-54.8174.9172.3-94.6000111.6F261 G285 L286 Y291 L292 F293 L412 L415 A416F261-F289 HydrophobicContact CE1-CB 3.73Å; F261-F289 AromaticContact CE1-CD1 3.93Å; F261-F289 HydrophobicContact CE1-CD1 3.93Å; F261-F289 HydrophobicContact CE1-CD2 4.21Å; F261-F289 AromaticContact CE1-CG 3.68Å; F261-F289 HydrophobicContact CE1-CG 3.68Å; F261-F289 HydrophobicContact CZ-CB 4.07Å; F261-F289 AromaticContact CZ-CD1 3.7Å; F261-F289 HydrophobicContact CZ-CD1 3.7Å; F261-F289 AromaticContact CZ-CD2 3.65Å; F261-F289 HydrophobicContact CZ-CD2 3.65Å; F261-F289 HydrophobicContact CZ-CE1 4.04Å; F261-F289 AromaticContact CZ-CE2 4Å; F261-F289 HydrophobicContact CZ-CE2 4Å; F261-F289 AromaticContact CZ-CG 3.51Å; F261-F289 HydrophobicContact CZ-CG 3.51Å; F261-F289 HydrophobicContact CZ-CZ 4.18Å; G285-F289 WeakPolarHBondContact O-CB 3.49Å; G285-F289 PolarHBondContact O-N 3.22Å; L286-F289 PolarHBondContact O-N 3.02Å; F289-Y291 VanDerWaalsContact C-N 3.32Å; F289-Y291 PolarHBondContact O-N 2.93Å; F289-L292 PolarHBondContact O-N 3.3Å; F289-F293 HydrophobicContact CE1-CB 4.5Å; F289-F293 HydrophobicContact CZ-CD2 4.43Å; F289-F293 WeakPolarHBondContact O-CB 3.44Å; F289-F293 PolarHBondContact O-N 3.41Å; F289-L412 HydrophobicContact CB-CB 4.47Å; F289-L412 WeakPolarHBondContact CD2-O 3.38Å; F289-L415 HydrophobicContact CE2-CB 4.18Å; F289-L415 HydrophobicContact CE2-CD2 3.98Å; F289-L415 HydrophobicContact CE2-CG 3.94Å; F289-A416 HydrophobicContact CD2-CB 3.73Å; F289-A416 HydrophobicContact CE2-CB 3.91Å; F289-A416 HydrophobicContact CG-CB 4.42Å; F289-A416 WeakPolarHBondContact O-CB 3.34Å
290I97.9Very high96.1Very high29 Ų2918 Ų1815%0.1499%0.085CC..Hα-helixtrans-62.4-42.7-177-63.5171.2000110.5L286 F293 L294 I446 P447 L450L286-I290 HydrophobicContact CD1-CD1 3.93Å; L286-I290 HydrophobicContact CD1-CG1 4.19Å; L286-I290 HydrophobicContact CG-CD1 3.91Å; L286-I290 WeakPolarHBondContact O-CG1 3.25Å; L286-I290 PolarHBondContact O-N 3.4Å; I290-F293 PolarHBondContact O-N 2.93Å; I290-L294 HydrophobicContact CG2-CD1 3.97Å; I290-L294 HydrophobicContact CG2-CG 4.42Å; I290-L294 WeakPolarHBondContact O-CG 3.41Å; I290-L294 PolarHBondContact O-N 2.93Å; I290-I446 HydrophobicContact CD1-CG2 3.79Å; I290-P447 HydrophobicContact CG2-CG 4.23Å; I290-L450 HydrophobicContact CD1-CD1 3.81Å
291Y98Very high96.3Very high0 Ų017.9 Ų17.90%08%0.084CC..Hα-helixtrans-55.4-54174.6167.3-95.4000111.4A287 F289 F293 F295 I352 L355 V385 I386 F444A287-Y291 WeakPolarHBondContact O-CB 3.22Å; A287-Y291 PolarHBondContact O-N 3.07Å; F289-Y291 VanDerWaalsContact C-N 3.32Å; F289-Y291 PolarHBondContact O-N 2.93Å; Y291-F293 VanDerWaalsContact C-N 3.29Å; Y291-F293 PolarHBondContact O-N 3.26Å; Y291-F295 HydrophobicContact CE1-CB 4.34Å; Y291-F295 HydrophobicContact CE1-CG 4.39Å; Y291-F295 WeakPolarHBondContact O-CB 3.49Å; Y291-F295 PolarHBondContact O-N 3.07Å; Y291-F295 WeakPolarHBondContact OH-CD2 3.47Å; Y291-I352 HydrophobicContact CD2-CG1 4.5Å; Y291-L355 HydrophobicContact CD2-CD1 4.33Å; Y291-L355 HydrophobicContact CE2-CD1 3.6Å; Y291-V385 HydrophobicContact CD1-CG1 3.67Å; Y291-V385 HydrophobicContact CD2-CB 4.28Å; Y291-V385 HydrophobicContact CD2-CG1 3.6Å; Y291-V385 HydrophobicContact CD2-CG2 4.33Å; Y291-V385 HydrophobicContact CE1-CB 4.01Å; Y291-V385 HydrophobicContact CE1-CG1 3.65Å; Y291-V385 HydrophobicContact CE2-CB 3.69Å; Y291-V385 HydrophobicContact CE2-CG1 3.53Å; Y291-V385 HydrophobicContact CE2-CG2 3.7Å; Y291-V385 HydrophobicContact CG-CG1 3.67Å; Y291-I386 HydrophobicContact CD1-CG1 4.49Å; Y291-I386 HydrophobicContact CE1-CD1 4.23Å; Y291-I386 HydrophobicContact CE1-CG1 3.74Å; Y291-F444 HydrophobicContact CD2-CD1 4.08Å; Y291-F444 AromaticContact CD2-CE1 3.6Å; Y291-F444 HydrophobicContact CD2-CE1 3.6Å; Y291-F444 AromaticContact CE2-CE1 3.96Å; Y291-F444 HydrophobicContact CE2-CE1 3.96Å; Y291-F444 HydrophobicContact CG-CE1 4.46Å
292L97.6Very high96.4Very high0 Ų018 Ų180%09%0.085CC..Hα-helixtrans-67.4-31.9-178.5-84.4176.9000112.7Y288 F289 F295 S296 I386 A416Y288-L292 HydrophobicContact CD1-CD1 3.94Å; Y288-L292 HydrophobicContact CE1-CD1 3.31Å; Y288-L292 HydrophobicContact CE1-CG 4.44Å; Y288-L292 HydrophobicContact CE2-CD1 4.23Å; Y288-L292 VanDerWaalsContact CZ-CD1 3.48Å; Y288-L292 WeakPolarHBondContact O-CB 3.48Å; Y288-L292 PolarHBondContact O-N 2.91Å; F289-L292 PolarHBondContact O-N 3.3Å; L292-F295 HydrophobicContact CD2-CD1 4.46Å; L292-S296 WeakPolarHBondContact O-CB 3.37Å; L292-S296 PolarHBondContact O-N 3.41Å; L292-S296 PolarHBondContact O-OG 2.88Å; L292-I386 HydrophobicContact CD2-CD1 3.75Å; L292-I386 HydrophobicContact CD2-CG1 4.34Å; L292-A416 HydrophobicContact CB-CB 3.69Å
293F97.8Very high96.4Very high32 Ų3216 Ų1614%0.148%0.078CC..Hα-helixtrans-64.2-50.5179.8173.4-95.4000110.2F289 I290 Y291 S296 G297 A416 M419 G420 L423F289-F293 HydrophobicContact CE1-CB 4.5Å; F289-F293 HydrophobicContact CZ-CD2 4.43Å; F289-F293 WeakPolarHBondContact O-CB 3.44Å; F289-F293 PolarHBondContact O-N 3.41Å; I290-F293 PolarHBondContact O-N 2.93Å; Y291-F293 VanDerWaalsContact C-N 3.29Å; Y291-F293 PolarHBondContact O-N 3.26Å; F293-S296 PolarHBondContact O-OG 3.1Å; F293-G297 PolarHBondContact O-N 3.23Å; F293-A416 HydrophobicContact CB-CB 4.02Å; F293-M419 HydrophobicContact CD2-CB 4.05Å; F293-M419 HydrophobicContact CE2-CB 3.71Å; F293-G420 WeakPolarHBondContact O-CA 3.46Å; F293-L423 HydrophobicContact CE1-CD2 4.04Å; F293-L423 HydrophobicContact CE2-CB 4.42Å; F293-L423 HydrophobicContact CZ-CB 3.84Å; F293-L423 HydrophobicContact CZ-CD1 3.97Å; F293-L423 HydrophobicContact CZ-CD2 3.86Å; F293-L423 HydrophobicContact CZ-CG 4.07Å
294L97.5Very high96.3Very high5 Ų514.7 Ų14.73%0.0267%0.072CC..Hα-helixtrans-67.5-45.4176-63172.6000111.6I290 G297 L298 C440 F443 F444I290-L294 HydrophobicContact CG2-CD1 3.97Å; I290-L294 HydrophobicContact CG2-CG 4.42Å; I290-L294 WeakPolarHBondContact O-CG 3.41Å; I290-L294 PolarHBondContact O-N 2.93Å; L294-G297 PolarHBondContact O-N 3.28Å; L294-L298 PolarHBondContact O-N 3.4Å; L294-C440 HydrophobicContact CD2-CB 4.27Å; L294-F443 VanDerWaalsContact CD1-C 3.45Å; L294-F443 HydrophobicContact CD1-CB 3.76Å; L294-F443 HydrophobicContact CD2-CB 3.97Å; L294-F444 HydrophobicContact CB-CD2 4.32Å; L294-F444 HydrophobicContact CB-CE1 3.95Å; L294-F444 HydrophobicContact CB-CE2 3.69Å; L294-F444 HydrophobicContact CB-CZ 3.5Å; L294-F444 VanDerWaalsContact CB-CZ 3.5Å; L294-F444 HydrophobicContact CD1-CD1 4.23Å; L294-F444 HydrophobicContact CD1-CD2 4.18Å; L294-F444 HydrophobicContact CD1-CE1 4.42Å; L294-F444 HydrophobicContact CD1-CE2 4.38Å; L294-F444 HydrophobicContact CD1-CG 4.11Å
295F96.9Very high96.3Very high8 Ų814.7 Ų14.74%0.0357%0.072CC..Hα-helixtrans-61-51.7-177.4175.1-89.8000112Y291 L292 G297 L298 E299 Y378 A382 F444Y291-F295 HydrophobicContact CE1-CB 4.34Å; Y291-F295 HydrophobicContact CE1-CG 4.39Å; Y291-F295 WeakPolarHBondContact O-CB 3.49Å; Y291-F295 PolarHBondContact O-N 3.07Å; Y291-F295 WeakPolarHBondContact OH-CD2 3.47Å; L292-F295 HydrophobicContact CD2-CD1 4.46Å; F295-G297 VanDerWaalsContact C-N 3.3Å; F295-G297 PolarHBondContact O-N 2.96Å; F295-L298 PolarHBondContact O-N 3.4Å; F295-E299 WeakPolarHBondContact CE1-OE2 3.44Å; F295-E299 WeakPolarHBondContact O-CB 3.42Å; F295-E299 PolarHBondContact O-N 2.92Å; F295-Y378 AromaticContact CD2-CE2 3.81Å; F295-Y378 HydrophobicContact CD2-CE2 3.81Å; F295-Y378 HydrophobicContact CE2-CD2 4.18Å; F295-Y378 AromaticContact CE2-CE2 3.2Å; F295-Y378 HydrophobicContact CE2-CE2 3.2Å; F295-Y378 AromaticContact CE2-CZ 3.43Å; F295-Y378 VanDerWaalsContact CE2-CZ 3.43Å; F295-Y378 VanDerWaalsContact CE2-OH 3.27Å; F295-Y378 WeakPolarHBondContact CE2-OH 3.39Å; F295-Y378 AromaticContact CZ-CE2 3.89Å; F295-Y378 HydrophobicContact CZ-CE2 3.89Å; F295-Y378 AromaticContact CZ-CZ 3.63Å; F295-Y378 WeakPolarHBondContact CZ-OH 3.12Å; F295-A382 HydrophobicContact CE2-CB 3.5Å; F295-A382 HydrophobicContact CZ-CB 3.93Å; F295-F444 HydrophobicContact CB-CE1 4.46Å; F295-F444 HydrophobicContact CB-CZ 4.12Å
296S96.1Very high96.3Very high6 Ų614.7 Ų14.74%0.0427%0.072CC..Hα-helixtrans-68.1-32.3-178.262.10000112.6L292 F293 Y300L292-S296 WeakPolarHBondContact O-CB 3.37Å; L292-S296 PolarHBondContact O-N 3.41Å; L292-S296 PolarHBondContact O-OG 2.88Å; F293-S296 PolarHBondContact O-OG 3.1Å; S296-Y300 VanDerWaalsContact O-CB 3.23Å; S296-Y300 WeakPolarHBondContact O-CB 3.49Å; S296-Y300 PolarHBondContact O-N 2.93Å
297G95.5Very high96.2Very high0 Ų012.6 Ų12.60%06%0.06CC..Hα-helixtrans-62.4-51.9173.600000112.9F293 L294 F295 Y300 T301 G420 S424F293-G297 PolarHBondContact O-N 3.23Å; L294-G297 PolarHBondContact O-N 3.28Å; F295-G297 VanDerWaalsContact C-N 3.3Å; F295-G297 PolarHBondContact O-N 2.96Å; G297-Y300 PolarHBondContact O-N 2.85Å; G297-T301 WeakPolarHBondContact O-CG2 3.5Å; G297-T301 PolarHBondContact O-N 2.91Å; G297-T301 PolarHBondContact O-OG1 3.16Å; G297-G420 VanDerWaalsContact CA-C 3.49Å; G297-G420 WeakPolarHBondContact CA-O 3.13Å; G297-S424 VanDerWaalsContact C-CB 3.5Å; G297-S424 WeakPolarHBondContact CA-OG 3.13Å; G297-S424 WeakPolarHBondContact O-CB 3.38Å
298L96.6Very high96Very high0 Ų016.9 Ų16.90%08%0.08CC..Hα-helixtrans-70.9-35.2178.5-67.6-178.2000113.4L294 F295 Y300 T301 L302 F359 F437 C440 F444L294-L298 PolarHBondContact O-N 3.4Å; F295-L298 PolarHBondContact O-N 3.4Å; L298-Y300 VanDerWaalsContact C-N 3.28Å; L298-Y300 PolarHBondContact O-N 3.49Å; L298-T301 WeakPolarHBondContact CA-OG1 3.37Å; L298-T301 PolarHBondContact O-OG1 3.48Å; L298-L302 WeakPolarHBondContact O-CB 3.39Å; L298-L302 PolarHBondContact O-N 3.37Å; L298-F359 HydrophobicContact CB-CD1 4.03Å; L298-F359 HydrophobicContact CB-CE1 3.51Å; L298-F359 HydrophobicContact CB-CZ 3.89Å; L298-F359 HydrophobicContact CD1-CB 4.16Å; L298-F359 HydrophobicContact CD1-CD1 3.53Å; L298-F359 HydrophobicContact CD1-CD2 3.71Å; L298-F359 HydrophobicContact CD1-CE1 3.69Å; L298-F359 HydrophobicContact CD1-CE2 3.87Å; L298-F359 HydrophobicContact CD1-CG 3.53Å; L298-F359 HydrophobicContact CD1-CZ 3.84Å; L298-F359 HydrophobicContact CG-CD1 4.39Å; L298-F359 HydrophobicContact CG-CE1 4.26Å; L298-F437 HydrophobicContact CB-CE1 4.27Å; L298-F437 HydrophobicContact CD2-CD1 3.98Å; L298-F437 HydrophobicContact CD2-CD2 4.17Å; L298-F437 HydrophobicContact CD2-CE1 4.1Å; L298-F437 HydrophobicContact CD2-CE2 4.3Å; L298-F437 HydrophobicContact CD2-CG 4.01Å; L298-F437 HydrophobicContact CD2-CZ 4.26Å; L298-C440 HydrophobicContact CD1-CB 3.76Å; L298-C440 HydrophobicContact CD2-CB 3.75Å; L298-C440 HydrophobicContact CG-CB 3.85Å; L298-F444 HydrophobicContact CD1-CE2 4.21Å
299E95.3Very high95.9Very high63 Ų6319.9 Ų19.929%0.2949%0.091SC..Hα-helixtrans-59.6-41.2172.3177.8179.4-130.300111.2F295 L302 Y378F295-E299 WeakPolarHBondContact CE1-OE2 3.44Å; F295-E299 WeakPolarHBondContact O-CB 3.42Å; F295-E299 PolarHBondContact O-N 2.92Å; E299-L302 WeakPolarHBondContact O-CB 3.3Å; E299-Y378 PolarHBondContact OE1-OH 3.4Å
300Y93.9Very high95.8Very high35 Ų3520.3 Ų20.314%0.1379%0.093CC..Hα-helixtrans-68.8-50.3177.1173.7-109.8000112.4V86 L87 S296 G297 L298 L302 S303 F304 P421 A425V86-Y300 HydrophobicContact CG1-CE2 3.88Å; V86-Y300 PolarHBondContact O-OH 2.79Å; L87-Y300 WeakPolarHBondContact CA-OH 3.47Å; S296-Y300 VanDerWaalsContact O-CB 3.23Å; S296-Y300 WeakPolarHBondContact O-CB 3.49Å; S296-Y300 PolarHBondContact O-N 2.93Å; G297-Y300 PolarHBondContact O-N 2.85Å; L298-Y300 VanDerWaalsContact C-N 3.28Å; L298-Y300 PolarHBondContact O-N 3.49Å; Y300-L302 PolarHBondContact O-N 2.88Å; Y300-S303 PolarHBondContact O-N 2.85Å; Y300-F304 HydrophobicContact CD1-CE2 4.33Å; Y300-F304 AromaticContact CE1-CE2 3.69Å; Y300-F304 HydrophobicContact CE1-CE2 3.69Å; Y300-F304 HydrophobicContact CE1-CZ 4.06Å; Y300-F304 AromaticContact CZ-CZ 4Å; Y300-P421 HydrophobicContact CD1-CB 3.61Å; Y300-P421 HydrophobicContact CD2-CB 4.48Å; Y300-P421 HydrophobicContact CE1-CB 4.11Å; Y300-P421 HydrophobicContact CG-CB 3.8Å; Y300-P421 HydrophobicContact CG-CG 4.39Å; Y300-A425 HydrophobicContact CE1-CB 4.09Å
301T95.4Very high95.6Very high0 Ų025 Ų250%012%0.115CC..Hα-helixtrans-69.4-15.4-178.458.10000113.7G297 L298 S303 F304 L305 Y428G297-T301 WeakPolarHBondContact O-CG2 3.5Å; G297-T301 PolarHBondContact O-N 2.91Å; G297-T301 PolarHBondContact O-OG1 3.16Å; L298-T301 WeakPolarHBondContact CA-OG1 3.37Å; L298-T301 PolarHBondContact O-OG1 3.48Å; T301-S303 PolarHBondContact O-N 3.08Å; T301-F304 HydrophobicContact CG2-CD2 4.21Å; T301-F304 WeakPolarHBondContact O-CA 3.35Å; T301-F304 WeakPolarHBondContact O-CB 3.34Å; T301-F304 PolarHBondContact O-N 3.04Å; T301-L305 PolarHBondContact O-N 3.09Å; T301-Y428 HydrophobicContact CG2-CD2 4.38Å; T301-Y428 HydrophobicContact CG2-CG 4.37Å
302L96Very high95.4Very high4 Ų426.1 Ų26.12%0.02112%0.119CC..Hα-helixtrans-55-32170.7-175.662.5000112.6L298 E299 Y300 F304 L305 T306 M320 I324 I362 L371 L375L298-L302 WeakPolarHBondContact O-CB 3.39Å; L298-L302 PolarHBondContact O-N 3.37Å; E299-L302 WeakPolarHBondContact O-CB 3.3Å; Y300-L302 PolarHBondContact O-N 2.88Å; L302-F304 VanDerWaalsContact C-N 3.33Å; L302-L305 PolarHBondContact O-N 3.26Å; L302-T306 HydrophobicContact CD1-CG2 4.04Å; L302-T306 HydrophobicContact CG-CG2 4.32Å; L302-T306 WeakPolarHBondContact O-CB 3.4Å; L302-T306 WeakPolarHBondContact O-CG2 3.31Å; L302-T306 PolarHBondContact O-N 3.05Å; L302-T306 PolarHBondContact O-OG1 2.89Å; L302-M320 HydrophobicContact CD2-CE 3.68Å; L302-M320 HydrophobicContact CD2-SD 4.1Å; L302-M320 HydrophobicContact CG-CE 3.89Å; L302-M320 HydrophobicContact CG-SD 4.3Å; L302-I324 HydrophobicContact CD2-CD1 4.37Å; L302-I362 HydrophobicContact CD1-CG2 3.6Å; L302-L371 HydrophobicContact CD1-CD1 4.4Å; L302-L375 HydrophobicContact CD1-CD2 4.39Å; L302-L375 HydrophobicContact CD2-CD2 3.81Å
303S92.8Very high95.1Very high21 Ų2128.6 Ų28.615%0.14714%0.137CC..Hα-helixtrans-67-34.2175.5-60.90000112.3Y300 T301 T306 H307 Q317Y300-S303 PolarHBondContact O-N 2.85Å; T301-S303 PolarHBondContact O-N 3.08Å; S303-T306 PolarHBondContact O-OG1 3.17Å; S303-H307 PolarHBondContact O-N 2.69Å; S303-Q317 PolarHBondContact O-NE2 3.44Å
304F93.4Very high94.4Very high1 Ų131 Ų310%0.00416%0.158CC..Hα-helixtrans-71.1-49.2172.8-58.3-48.9000110.8Y83 V86 Y300 T301 L302 T306 H307 Q308 A425 Y428 W429Y83-F304 AromaticContact CD1-CD1 3.87Å; Y83-F304 HydrophobicContact CD1-CD1 3.87Å; Y83-F304 HydrophobicContact CD1-CE1 4.33Å; Y83-F304 HydrophobicContact CE1-CD1 4.47Å; V86-F304 HydrophobicContact CB-CD1 4.43Å; V86-F304 HydrophobicContact CB-CE1 3.64Å; V86-F304 HydrophobicContact CB-CZ 4.2Å; V86-F304 HydrophobicContact CG1-CD1 4.07Å; V86-F304 HydrophobicContact CG1-CE1 3.37Å; V86-F304 HydrophobicContact CG1-CE2 4.45Å; V86-F304 HydrophobicContact CG1-CZ 3.58Å; Y300-F304 HydrophobicContact CD1-CE2 4.33Å; Y300-F304 AromaticContact CE1-CE2 3.69Å; Y300-F304 HydrophobicContact CE1-CE2 3.69Å; Y300-F304 HydrophobicContact CE1-CZ 4.06Å; Y300-F304 AromaticContact CZ-CZ 4Å; T301-F304 HydrophobicContact CG2-CD2 4.21Å; T301-F304 WeakPolarHBondContact O-CA 3.35Å; T301-F304 WeakPolarHBondContact O-CB 3.34Å; T301-F304 PolarHBondContact O-N 3.04Å; L302-F304 VanDerWaalsContact C-N 3.33Å; F304-T306 PolarHBondContact O-N 2.92Å; F304-H307 PolarHBondContact O-N 3.32Å; F304-Q308 WeakPolarHBondContact O-CB 3.33Å; F304-Q308 PolarHBondContact O-N 3.47Å; F304-A425 HydrophobicContact CE2-CB 4.33Å; F304-Y428 HydrophobicContact CB-CD1 4.25Å; F304-Y428 HydrophobicContact CB-CE1 3.66Å; F304-Y428 HydrophobicContact CB-CE2 4.29Å; F304-Y428 HydrophobicContact CD2-CD1 4.39Å; F304-Y428 HydrophobicContact CG-CE1 4.46Å; F304-W429 HydrophobicContact CB-CZ2 4.27Å; F304-W429 AromaticContact CD1-CZ2 3.77Å; F304-W429 HydrophobicContact CD1-CZ2 3.77Å; F304-W429 HydrophobicContact CD2-CZ2 4.32Å; F304-W429 AromaticContact CD2-NE1 3.95Å; F304-W429 HydrophobicContact CE1-CZ2 4.1Å; F304-W429 AromaticContact CE2-NE1 3.76Å; F304-W429 AromaticContact CG-CZ2 3.89Å; F304-W429 HydrophobicContact CG-CZ2 3.89Å; F304-W429 AromaticContact CZ-NE1 3.99Å
305L96.5Very high93.9Very high0 Ų036.4 Ų36.40%018%0.184CC..Hα-helixtrans-56-49.5-178.5-174.7154.4000112.1T301 L302 H307 Q308 R309 F310 I362 Y428 A433 F437T301-L305 PolarHBondContact O-N 3.09Å; L302-L305 PolarHBondContact O-N 3.26Å; L305-H307 VanDerWaalsContact C-N 3.29Å; L305-H307 PolarHBondContact O-N 3.12Å; L305-Q308 PolarHBondContact O-N 3.05Å; L305-R309 WeakPolarHBondContact O-CB 3.28Å; L305-R309 PolarHBondContact O-N 3.18Å; L305-F310 HydrophobicContact CD2-CD2 4.47Å; L305-F310 HydrophobicContact CD2-CE2 4.08Å; L305-I362 HydrophobicContact CD1-CG2 4.22Å; L305-Y428 WeakPolarHBondContact CA-OH 2.98Å; L305-Y428 HydrophobicContact CB-CE2 4.11Å; L305-Y428 PolarHBondContact N-OH 3.24Å; L305-A433 HydrophobicContact CD1-CB 4.26Å; L305-F437 HydrophobicContact CB-CE2 4.34Å; L305-F437 HydrophobicContact CD1-CD2 3.85Å; L305-F437 HydrophobicContact CD1-CE1 4.37Å; L305-F437 HydrophobicContact CD1-CE2 3.54Å; L305-F437 HydrophobicContact CD1-CG 4.39Å; L305-F437 HydrophobicContact CD1-CZ 3.83Å
306T96.4Very high93.6Very high0 Ų040 Ų400%020%0.201CC..Hα-helixtrans-67.4-31.9-17752.50000112.9L302 S303 F304 F310 Q311 F312 Q317 M320 L371L302-T306 HydrophobicContact CD1-CG2 4.04Å; L302-T306 HydrophobicContact CG-CG2 4.32Å; L302-T306 WeakPolarHBondContact O-CB 3.4Å; L302-T306 WeakPolarHBondContact O-CG2 3.31Å; L302-T306 PolarHBondContact O-N 3.05Å; L302-T306 PolarHBondContact O-OG1 2.89Å; S303-T306 PolarHBondContact O-OG1 3.17Å; F304-T306 PolarHBondContact O-N 2.92Å; T306-F310 CarbonylContact O-C 3.58Å; T306-F310 WeakPolarHBondContact O-CB 3.44Å; T306-F310 PolarHBondContact O-N 2.86Å; T306-Q311 PolarHBondContact O-N 3.31Å; T306-F312 HydrophobicContact CG2-CD2 4.25Å; T306-F312 HydrophobicContact CG2-CE2 4.49Å; T306-F312 WeakPolarHBondContact O-CB 3.29Å; T306-F312 PolarHBondContact O-N 3.19Å; T306-F312 VanDerWaalsContact O-N 3.15Å; T306-Q317 PolarHBondContact OG1-NE2 2.91Å; T306-M320 HydrophobicContact CG2-CE 4.3Å; T306-M320 HydrophobicContact CG2-SD 3.72Å; T306-L371 HydrophobicContact CG2-CD2 4.01Å
307H93.4Very high93.4Very high19 Ų1940.6 Ų40.69%0.08820%0.203CC..Hα-helixtrans-74.8-50.6174.3-169.749000111.4E80 K82 Y83 S303 F304 L305 R309 Q311 F312E80-H307 IonicContact OE1-CD2 2.67Å; E80-H307 IonicContact OE1-NE2 2.69Å; E80-H307 PolarHBondContact OE1-NE2 3.46Å; K82-H307 PolarHBondContact NZ-ND1 2.94Å; Y83-H307 AromaticContact CE1-CD2 3.62Å; Y83-H307 AromaticContact CZ-CD2 3.99Å; S303-H307 PolarHBondContact O-N 2.69Å; F304-H307 PolarHBondContact O-N 3.32Å; L305-H307 VanDerWaalsContact C-N 3.29Å; L305-H307 PolarHBondContact O-N 3.12Å; H307-R309 PolarHBondContact O-N 2.95Å; H307-Q311 WeakPolarHBondContact O-CA 3.33Å; H307-Q311 PolarHBondContact O-N 3.3Å; H307-Q311 PolarHBondContact O-NE2 3.07Å; H307-F312 PolarHBondContact ND1-O 3.43Å
308Q93.6Very high93.1Very high92 Ų9242.5 Ų42.543%0.4322%0.223SC..Hα-helixtrans-62.8-45.8-176.1-171.6178.59.400112.1F304 L305 Q311 Y428F304-Q308 WeakPolarHBondContact O-CB 3.33Å; F304-Q308 PolarHBondContact O-N 3.47Å; L305-Q308 PolarHBondContact O-N 3.05Å; Q308-Q311 PolarHBondContact O-NE2 3.41Å; Q308-Y428 PolarHBondContact OE1-OH 2.77Å
309R95.5Very high92.8Very high73 Ų7349.2 Ų49.228%0.27525%0.252SS..Hα-helixtrans-89.4-38.9-173.1-166.3177.2-68.1161.41.9114.1L305 H307 G363 A365 E434L305-R309 WeakPolarHBondContact O-CB 3.28Å; L305-R309 PolarHBondContact O-N 3.18Å; H307-R309 PolarHBondContact O-N 2.95Å; R309-G363 VanDerWaalsContact CZ-O 3.26Å; R309-G363 PolarHBondContact NH1-O 2.97Å; R309-G363 PolarHBondContact NH2-O 2.9Å; R309-A365 WeakPolarHBondContact CD-O 3.37Å; R309-A365 VanDerWaalsContact NH1-N 3.16Å; R309-A365 PolarHBondContact NH1-O 2.68Å; R309-E434 IonicContact CZ-OE1 3.17Å; R309-E434 VanDerWaalsContact NH2-CD 3.27Å; R309-E434 IonicContact NH2-OE1 3.55Å; R309-E434 PolarHBondContact NH2-OE1 3.12Å; R309-E434 IonicContact NH2-OE2 2.8Å
310F96Very high92.8Very high39 Ų3946.8 Ų46.817%0.17124%0.241CC..Hα-helixtrans-110.81-174.3-58.1-73.9000113.6L305 T306 F312 A365 V368 L371L305-F310 HydrophobicContact CD2-CD2 4.47Å; L305-F310 HydrophobicContact CD2-CE2 4.08Å; T306-F310 CarbonylContact O-C 3.58Å; T306-F310 WeakPolarHBondContact O-CB 3.44Å; T306-F310 PolarHBondContact O-N 2.86Å; F310-F312 HydrophobicContact CB-CD1 3.49Å; F310-F312 VanDerWaalsContact CB-CD1 3.49Å; F310-F312 HydrophobicContact CB-CE1 3.54Å; F310-F312 HydrophobicContact CB-CG 4.31Å; F310-F312 HydrophobicContact CB-CZ 4.38Å; F310-F312 HydrophobicContact CG-CE1 4.29Å; F310-F312 PolarHBondContact O-N 3.2Å; F310-F312 VanDerWaalsContact O-N 3.15Å; F310-A365 HydrophobicContact CE2-CB 4.13Å; F310-A365 HydrophobicContact CZ-CB 3.74Å; F310-A365 WeakPolarHBondContact CZ-O 3.48Å; F310-V368 HydrophobicContact CD1-CG2 4.14Å; F310-L371 HydrophobicContact CD2-CD2 4.01Å; F310-L371 HydrophobicContact CE2-CB 4.32Å; F310-L371 HydrophobicContact CE2-CD2 3.87Å; F310-L371 HydrophobicContact CE2-CG 4.49Å; F310-L371 HydrophobicContact CZ-CB 4.34Å
311Q94Very high92.7Very high127 Ų12748.4 Ų48.459%0.59325%0.249SC*.  trans54.532.9-177.8-62.4-62.8-45.100112.5T306 H307 Q308 S313T306-Q311 PolarHBondContact O-N 3.31Å; H307-Q311 WeakPolarHBondContact O-CA 3.33Å; H307-Q311 PolarHBondContact O-N 3.3Å; H307-Q311 PolarHBondContact O-NE2 3.07Å; Q308-Q311 PolarHBondContact O-NE2 3.41Å; Q311-S313 PolarHBondContact O-N 3.49Å
312F93.8Very high92.6Very high23 Ų2352.2 Ų52.210%0.10127%0.266CS..  trans-61.1128.1179.9-83.616.3000110.5K82 T306 H307 F310 Q316 Q317 V368 L371K82-F312 PolarHBondContact NZ-O 3.48Å; T306-F312 HydrophobicContact CG2-CD2 4.25Å; T306-F312 HydrophobicContact CG2-CE2 4.49Å; T306-F312 WeakPolarHBondContact O-CB 3.29Å; T306-F312 PolarHBondContact O-N 3.19Å; T306-F312 VanDerWaalsContact O-N 3.15Å; H307-F312 PolarHBondContact ND1-O 3.43Å; F310-F312 HydrophobicContact CB-CD1 3.49Å; F310-F312 VanDerWaalsContact CB-CD1 3.49Å; F310-F312 HydrophobicContact CB-CE1 3.54Å; F310-F312 HydrophobicContact CB-CG 4.31Å; F310-F312 HydrophobicContact CB-CZ 4.38Å; F310-F312 HydrophobicContact CG-CE1 4.29Å; F310-F312 PolarHBondContact O-N 3.2Å; F310-F312 VanDerWaalsContact O-N 3.15Å; F312-Q316 HydrophobicContact CB-CB 4.03Å; F312-Q316 HydrophobicContact CD1-CB 4.4Å; F312-Q316 HydrophobicContact CD2-CB 3.98Å; F312-Q316 HydrophobicContact CG-CB 3.9Å; F312-Q317 HydrophobicContact CB-CG 4.05Å; F312-Q317 HydrophobicContact CD2-CG 4.44Å; F312-V368 HydrophobicContact CE1-CG2 4.2Å; F312-V368 HydrophobicContact CZ-CG1 4.4Å; F312-V368 HydrophobicContact CZ-CG2 4.3Å; F312-L371 HydrophobicContact CE2-CD2 4.26Å; F312-L371 HydrophobicContact CZ-CD2 4.29Å
313S90.3Very high92.6Very high52 Ų5256.1 Ų56.136%0.36428%0.283SS..  trans-65.3162.5164.262.30000111Q311 M315 Q316 Q317Q311-S313 PolarHBondContact O-N 3.49Å; S313-M315 PolarHBondContact O-N 3.38Å; S313-Q316 PolarHBondContact O-N 2.86Å; S313-Q316 VanDerWaalsContact O-N 3.1Å; S313-Q316 WeakPolarHBondContact OG-CG 3.45Å; S313-Q316 PolarHBondContact OG-N 3.22Å; S313-Q316 PolarHBondContact OG-OE1 3.21Å; S313-Q317 PolarHBondContact O-N 2.88Å
314S84.3Confident92.8Very high84 Ų8455.4 Ų55.459%0.58728%0.277SS*.Hα-helixtrans-59.1-33175.2-49.90000112.1Q317 G318S314-Q317 PolarHBondContact O-N 3.27Å; S314-G318 PolarHBondContact O-N 3.31Å
315M85.9Confident92.9Very high117 Ų11755.7 Ų55.758%0.57628%0.28SS*.Hα-helixtrans-65.7-41.5174.5-178.85969.300112.2S313 G318 K319S313-M315 PolarHBondContact O-N 3.38Å; M315-G318 PolarHBondContact O-N 2.98Å; M315-K319 WeakPolarHBondContact O-CG 3.19Å; M315-K319 PolarHBondContact O-N 3.13Å
316Q91.3Very high92.9Very high85 Ų8558.6 Ų58.640%0.39730%0.295SS..Hα-helixtrans-67.2-38.8176.3-75.3162.8-48.100111.9F312 S313 G318 K319 M320F312-Q316 HydrophobicContact CB-CB 4.03Å; F312-Q316 HydrophobicContact CD1-CB 4.4Å; F312-Q316 HydrophobicContact CD2-CB 3.98Å; F312-Q316 HydrophobicContact CG-CB 3.9Å; S313-Q316 PolarHBondContact O-N 2.86Å; S313-Q316 VanDerWaalsContact O-N 3.1Å; S313-Q316 WeakPolarHBondContact OG-CG 3.45Å; S313-Q316 PolarHBondContact OG-N 3.22Å; S313-Q316 PolarHBondContact OG-OE1 3.21Å; Q316-G318 VanDerWaalsContact C-N 3.31Å; Q316-G318 PolarHBondContact O-N 3Å; Q316-K319 PolarHBondContact O-N 3.07Å; Q316-M320 WeakPolarHBondContact O-CB 3.26Å; Q316-M320 PolarHBondContact O-N 2.59Å
317Q90.9Very high92.9Very high17 Ų1759.6 Ų59.68%0.07930%0.301CS..Hα-helixtrans-62.2-39.6171.2-69.9175.9-15.600111.5S303 T306 F312 S313 S314 M320 F321S303-Q317 PolarHBondContact O-NE2 3.44Å; T306-Q317 PolarHBondContact OG1-NE2 2.91Å; F312-Q317 HydrophobicContact CB-CG 4.05Å; F312-Q317 HydrophobicContact CD2-CG 4.44Å; S313-Q317 PolarHBondContact O-N 2.88Å; S314-Q317 PolarHBondContact O-N 3.27Å; Q317-M320 WeakPolarHBondContact O-CB 3.44Å; Q317-M320 PolarHBondContact O-N 2.92Å; Q317-F321 VanDerWaalsContact O-CD2 3.24Å; Q317-F321 WeakPolarHBondContact O-CD2 3.36Å; Q317-F321 PolarHBondContact O-N 2.99Å
318G89.1Confident93.1Very high40 Ų4060 Ų6041%0.41230%0.303SS..Hα-helixtrans-58.4-47.7171.900000112.9S314 M315 Q316 M320 F321 F322S314-G318 PolarHBondContact O-N 3.31Å; M315-G318 PolarHBondContact O-N 2.98Å; Q316-G318 VanDerWaalsContact C-N 3.31Å; Q316-G318 PolarHBondContact O-N 3Å; G318-M320 VanDerWaalsContact C-N 3.29Å; G318-M320 PolarHBondContact O-N 3.37Å; G318-F321 PolarHBondContact O-N 3.35Å; G318-F322 WeakPolarHBondContact O-CB 3.38Å; G318-F322 PolarHBondContact O-N 3.36Å
319K91.3Very high93.3Very high142 Ų14256.1 Ų56.162%0.61729%0.287SS*.Hα-helixtrans-61.3-36.9175-70.1179-179.1-177.20112.5M315 Q316 F322 F323M315-K319 WeakPolarHBondContact O-CG 3.19Å; M315-K319 PolarHBondContact O-N 3.13Å; Q316-K319 PolarHBondContact O-N 3.07Å; K319-F322 WeakPolarHBondContact O-CB 3.24Å; K319-F322 PolarHBondContact O-N 3.44Å; K319-F323 PolarHBondContact O-N 2.98Å
320M94.7Very high93.4Very high12 Ų1257.3 Ų57.36%0.05930%0.302CS..Hα-helixtrans-64.1-50.4175.7179.6-169.571.300111.6L302 T306 Q316 Q317 G318 F322 F323 I324 L375L302-M320 HydrophobicContact CD2-CE 3.68Å; L302-M320 HydrophobicContact CD2-SD 4.1Å; L302-M320 HydrophobicContact CG-CE 3.89Å; L302-M320 HydrophobicContact CG-SD 4.3Å; T306-M320 HydrophobicContact CG2-CE 4.3Å; T306-M320 HydrophobicContact CG2-SD 3.72Å; Q316-M320 WeakPolarHBondContact O-CB 3.26Å; Q316-M320 PolarHBondContact O-N 2.59Å; Q317-M320 WeakPolarHBondContact O-CB 3.44Å; Q317-M320 PolarHBondContact O-N 2.92Å; G318-M320 VanDerWaalsContact C-N 3.29Å; G318-M320 PolarHBondContact O-N 3.37Å; M320-F322 VanDerWaalsContact C-N 3.28Å; M320-F322 PolarHBondContact O-N 3.03Å; M320-F323 WeakPolarHBondContact O-CB 3.32Å; M320-F323 PolarHBondContact O-N 3.01Å; M320-I324 HydrophobicContact CG-CD1 4.17Å; M320-I324 WeakPolarHBondContact O-CG1 3.38Å; M320-I324 PolarHBondContact O-N 3.01Å; M320-L375 HydrophobicContact CG-CD1 3.45Å; M320-L375 VanDerWaalsContact CG-CD1 3.45Å; M320-L375 HydrophobicContact SD-CD1 3.74Å
321F92.6Very high93.4Very high69 Ų6956.8 Ų56.830%0.30330%0.301SS..Hα-helixtrans-65.5-31.9177-76.3-64.7000112.6Q317 G318 I324 G325Q317-F321 VanDerWaalsContact O-CD2 3.24Å; Q317-F321 WeakPolarHBondContact O-CD2 3.36Å; Q317-F321 PolarHBondContact O-N 2.99Å; G318-F321 PolarHBondContact O-N 3.35Å; F321-I324 HydrophobicContact CD1-CD1 4.03Å; F321-I324 HydrophobicContact CE1-CD1 4.38Å; F321-I324 PolarHBondContact O-N 3.32Å; F321-G325 PolarHBondContact O-N 2.92Å
322F93.7Very high93.5Very high80 Ų8051.1 Ų51.135%0.35128%0.275SS..Hα-helixtrans-60.1-48.6170.6178.9-92.7000111.9T189 M193 G318 K319 M320 I324 G325 I326T189-F322 HydrophobicContact CG2-CD2 3.21Å; T189-F322 HydrophobicContact CG2-CE2 3.49Å; T189-F322 VanDerWaalsContact CG2-CE2 3.49Å; T189-F322 HydrophobicContact CG2-CG 4.07Å; M193-F322 HydrophobicContact CE-CD2 4.29Å; M193-F322 HydrophobicContact CE-CE2 4.13Å; M193-F322 HydrophobicContact CG-CD2 4.44Å; M193-F322 HydrophobicContact SD-CD2 3.2Å; M193-F322 WeakPolarHBondContact SD-CD2 3.44Å; M193-F322 HydrophobicContact SD-CE2 3.34Å; M193-F322 WeakPolarHBondContact SD-CE2 3.47Å; M193-F322 HydrophobicContact SD-CG 4.3Å; G318-F322 WeakPolarHBondContact O-CB 3.38Å; G318-F322 PolarHBondContact O-N 3.36Å; K319-F322 WeakPolarHBondContact O-CB 3.24Å; K319-F322 PolarHBondContact O-N 3.44Å; M320-F322 VanDerWaalsContact C-N 3.28Å; M320-F322 PolarHBondContact O-N 3.03Å; F322-I324 VanDerWaalsContact C-N 3.34Å; F322-I324 PolarHBondContact O-N 2.99Å; F322-G325 PolarHBondContact O-N 3.35Å; F322-I326 HydrophobicContact CD1-CG1 4.3Å; F322-I326 HydrophobicContact CD2-CG1 4.45Å; F322-I326 HydrophobicContact CE1-CG1 3.87Å; F322-I326 HydrophobicContact CE2-CD1 4.33Å; F322-I326 HydrophobicContact CE2-CG1 4.05Å; F322-I326 HydrophobicContact CZ-CD1 4.21Å; F322-I326 HydrophobicContact CZ-CG1 3.74Å; F322-I326 WeakPolarHBondContact O-CG1 3.07Å; F322-I326 PolarHBondContact O-N 3.47Å
323F95.3Very high93.4Very high86 Ų8651.3 Ų51.338%0.37728%0.283SS..Hα-helixtrans-58.9-45.3175.8169.6-100.4000111.9K319 M320 T327 L375 L376K319-F323 PolarHBondContact O-N 2.98Å; M320-F323 WeakPolarHBondContact O-CB 3.32Å; M320-F323 PolarHBondContact O-N 3.01Å; F323-T327 VanDerWaalsContact O-CB 3.31Å; F323-T327 WeakPolarHBondContact O-CB 3.19Å; F323-T327 PolarHBondContact O-N 2.66Å; F323-T327 PolarHBondContact O-OG1 2.79Å; F323-L375 HydrophobicContact CE1-CB 4.41Å; F323-L376 HydrophobicContact CZ-CB 4.42Å; F323-L376 HydrophobicContact CZ-CD1 4.19Å
324I96.1Very high93.6Very high5 Ų549.9 Ų49.93%0.02628%0.276CS..Hα-helixtrans-58.7-51177.5-70.2167.4000110.4L302 M320 F321 F322 T327 M328 L375 Y378 S379L302-I324 HydrophobicContact CD2-CD1 4.37Å; M320-I324 HydrophobicContact CG-CD1 4.17Å; M320-I324 WeakPolarHBondContact O-CG1 3.38Å; M320-I324 PolarHBondContact O-N 3.01Å; F321-I324 HydrophobicContact CD1-CD1 4.03Å; F321-I324 HydrophobicContact CE1-CD1 4.38Å; F321-I324 PolarHBondContact O-N 3.32Å; F322-I324 VanDerWaalsContact C-N 3.34Å; F322-I324 PolarHBondContact O-N 2.99Å; I324-T327 PolarHBondContact O-N 3Å; I324-M328 HydrophobicContact CG2-CG 4.48Å; I324-M328 HydrophobicContact CG2-SD 3.82Å; I324-M328 WeakPolarHBondContact O-CB 3.34Å; I324-M328 VanDerWaalsContact O-CG 3.28Å; I324-M328 WeakPolarHBondContact O-CG 3.38Å; I324-M328 PolarHBondContact O-N 2.8Å; I324-L375 HydrophobicContact CD1-CD2 3.94Å; I324-L375 HydrophobicContact CG1-CD2 4.49Å; I324-Y378 HydrophobicContact CD1-CE1 4.25Å; I324-Y378 HydrophobicContact CG2-CD1 4.3Å; I324-Y378 HydrophobicContact CG2-CE1 3.75Å; I324-S379 WeakPolarHBondContact CA-OG 3.2Å; I324-S379 PolarHBondContact O-OG 3.36Å
325G95.6Very high94.1Very high7 Ų750.8 Ų50.87%0.07227%0.268CS..Hα-helixtrans-68-41.7-174.600000113.5S185 T189 F321 F322 M328 A329S185-G325 WeakPolarHBondContact CB-O 3.16Å; T189-G325 VanDerWaalsContact OG1-CA 3.27Å; T189-G325 WeakPolarHBondContact OG1-CA 3.45Å; F321-G325 PolarHBondContact O-N 2.92Å; F322-G325 PolarHBondContact O-N 3.35Å; G325-M328 PolarHBondContact O-N 2.95Å; G325-A329 WeakPolarHBondContact O-CB 3.42Å; G325-A329 PolarHBondContact O-N 3.44Å
326I96.8Very high94.5Very high62 Ų6245.5 Ų45.532%0.31824%0.242SC..Hα-helixtrans-62.5-45.2173.5-68.3-60.9000111T189 F322 M328 A329 V330T189-I326 HydrophobicContact CG2-CD1 3.86Å; T189-I326 HydrophobicContact CG2-CG1 3.92Å; F322-I326 HydrophobicContact CD1-CG1 4.3Å; F322-I326 HydrophobicContact CD2-CG1 4.45Å; F322-I326 HydrophobicContact CE1-CG1 3.87Å; F322-I326 HydrophobicContact CE2-CD1 4.33Å; F322-I326 HydrophobicContact CE2-CG1 4.05Å; F322-I326 HydrophobicContact CZ-CD1 4.21Å; F322-I326 HydrophobicContact CZ-CG1 3.74Å; F322-I326 WeakPolarHBondContact O-CG1 3.07Å; F322-I326 PolarHBondContact O-N 3.47Å; I326-M328 VanDerWaalsContact C-N 3.32Å; I326-M328 PolarHBondContact O-N 3.48Å; I326-A329 PolarHBondContact O-N 2.92Å; I326-V330 HydrophobicContact CG2-CG2 4.47Å; I326-V330 WeakPolarHBondContact O-CG2 3.42Å; I326-V330 PolarHBondContact O-N 3.37Å
327T97.4Very high94.6Very high21 Ų2146.1 Ų46.113%0.12924%0.241CC..Hα-helixtrans-59.3-46177.3-580000110.6F323 I324 A329 V330 I331 L376F323-T327 VanDerWaalsContact O-CB 3.31Å; F323-T327 WeakPolarHBondContact O-CB 3.19Å; F323-T327 PolarHBondContact O-N 2.66Å; F323-T327 PolarHBondContact O-OG1 2.79Å; I324-T327 PolarHBondContact O-N 3Å; T327-A329 PolarHBondContact O-N 2.64Å; T327-V330 PolarHBondContact O-N 2.74Å; T327-I331 HydrophobicContact CG2-CG1 4.46Å; T327-I331 WeakPolarHBondContact O-CG1 3.44Å; T327-I331 PolarHBondContact O-N 2.99Å; T327-L376 HydrophobicContact CG2-CD1 3.94Å
328M97.4Very high94.6Very high26 Ų2654.4 Ų54.413%0.12827%0.272CS..Hα-helixtrans-61-43.3177-73.7177.567.700112.4S185 I324 G325 I326 V330 I331 Q332 S379 A382 A383S185-M328 WeakPolarHBondContact OG-CB 3.22Å; I324-M328 HydrophobicContact CG2-CG 4.48Å; I324-M328 HydrophobicContact CG2-SD 3.82Å; I324-M328 WeakPolarHBondContact O-CB 3.34Å; I324-M328 VanDerWaalsContact O-CG 3.28Å; I324-M328 WeakPolarHBondContact O-CG 3.38Å; I324-M328 PolarHBondContact O-N 2.8Å; G325-M328 PolarHBondContact O-N 2.95Å; I326-M328 VanDerWaalsContact C-N 3.32Å; I326-M328 PolarHBondContact O-N 3.48Å; M328-V330 PolarHBondContact O-N 2.98Å; M328-I331 PolarHBondContact O-N 2.9Å; M328-Q332 VanDerWaalsContact O-CB 3.27Å; M328-Q332 WeakPolarHBondContact O-CB 3.48Å; M328-Q332 VanDerWaalsContact O-CG 3.24Å; M328-Q332 WeakPolarHBondContact O-CG 3.35Å; M328-Q332 PolarHBondContact O-N 3.33Å; M328-Q332 PolarHBondContact O-OE1 3.35Å; M328-S379 WeakPolarHBondContact CG-O 3.49Å; M328-A382 HydrophobicContact CE-CB 3.81Å; M328-A382 HydrophobicContact SD-CB 4.1Å; M328-A383 HydrophobicContact CB-CB 4.34Å; M328-A383 HydrophobicContact CG-CB 4.32Å
329A96.7Very high94.9Very high12 Ų1253.5 Ų53.510%0.09926%0.257CS..Hα-helixtrans-61-43177.400000112V182 L186 G325 I326 T327 Q332 G333V182-A329 HydrophobicContact CG1-CB 4.47Å; L186-A329 HydrophobicContact CD2-CB 3.95Å; L186-A329 HydrophobicContact CG-CB 4.19Å; G325-A329 WeakPolarHBondContact O-CB 3.42Å; G325-A329 PolarHBondContact O-N 3.44Å; I326-A329 PolarHBondContact O-N 2.92Å; T327-A329 PolarHBondContact O-N 2.64Å; A329-Q332 PolarHBondContact O-N 3.39Å; A329-G333 PolarHBondContact O-N 3.28Å
330V97.6Very high94.9Very high97 Ų9754 Ų5459%0.58826%0.259SS*.Hα-helixtrans-63.9-46.4177171.80000111I326 T327 M328 G334I326-V330 HydrophobicContact CG2-CG2 4.47Å; I326-V330 WeakPolarHBondContact O-CG2 3.42Å; I326-V330 PolarHBondContact O-N 3.37Å; T327-V330 PolarHBondContact O-N 2.74Å; M328-V330 PolarHBondContact O-N 2.98Å; V330-G334 WeakPolarHBondContact O-CA 3.39Å; V330-G334 PolarHBondContact O-N 3.22Å
331I97.5Very high94.6Very high29 Ų2956.3 Ų56.315%0.14928%0.275CS..Hα-helixtrans-67.8-38.6179-62.2-54.7000111.4T327 M328 Y335 A336 F380 A383 I384T327-I331 HydrophobicContact CG2-CG1 4.46Å; T327-I331 WeakPolarHBondContact O-CG1 3.44Å; T327-I331 PolarHBondContact O-N 2.99Å; M328-I331 PolarHBondContact O-N 2.9Å; I331-Y335 CarbonylContact O-C 3.57Å; I331-Y335 WeakPolarHBondContact O-CA 3.37Å; I331-Y335 WeakPolarHBondContact O-CB 3.44Å; I331-Y335 PolarHBondContact O-N 2.94Å; I331-A336 PolarHBondContact O-N 3.44Å; I331-F380 HydrophobicContact CD1-CD2 3.57Å; I331-F380 HydrophobicContact CD1-CE2 3.78Å; I331-F380 HydrophobicContact CG1-CD2 3.84Å; I331-F380 HydrophobicContact CG1-CE2 4.41Å; I331-F380 HydrophobicContact CG2-CD2 4.07Å; I331-F380 HydrophobicContact CG2-CE2 4.21Å; I331-A383 HydrophobicContact CB-CB 3.72Å; I331-A383 HydrophobicContact CG2-CB 3.56Å; I331-I384 HydrophobicContact CG2-CG1 4.33Å
332Q95.3Very high94.4Very high8 Ų855 Ų554%0.03728%0.281CS..Hα-helixtrans-66.7-49176.8-76.6161.9-16.600112.1G181 V182 S185 M328 A329 R337 A383G181-Q332 VanDerWaalsContact C-CD 3.42Å; G181-Q332 PolarHBondContact O-OE1 3.39Å; V182-Q332 HydrophobicContact CG2-CB 3.58Å; S185-Q332 PolarHBondContact OG-OE1 2.98Å; M328-Q332 VanDerWaalsContact O-CB 3.27Å; M328-Q332 WeakPolarHBondContact O-CB 3.48Å; M328-Q332 VanDerWaalsContact O-CG 3.24Å; M328-Q332 WeakPolarHBondContact O-CG 3.35Å; M328-Q332 PolarHBondContact O-N 3.33Å; M328-Q332 PolarHBondContact O-OE1 3.35Å; A329-Q332 PolarHBondContact O-N 3.39Å; Q332-R337 WeakPolarHBondContact O-CB 3.45Å; Q332-R337 PolarHBondContact O-N 3.25Å; Q332-A383 HydrophobicContact CG-CB 3.85Å; Q332-A383 WeakPolarHBondContact CG-O 3.38Å
333G92.7Very high94.4Very high27 Ų2754.1 Ų54.128%0.27828%0.28SS..Hα-helixtrans-71.2-32.8-179.400000113.2A329A329-G333 PolarHBondContact O-N 3.28Å
334G93.9Very high94.3Very high21 Ų2150.7 Ų50.722%0.21627%0.265CS..Hα-helixtrans-89.7-62.5-178.600000113.8V330 R338V330-G334 WeakPolarHBondContact O-CA 3.39Å; V330-G334 PolarHBondContact O-N 3.22Å; G334-R338 VanDerWaalsContact O-CD 3.22Å; G334-R338 WeakPolarHBondContact O-CD 3.38Å; G334-R338 VanDerWaalsContact O-CG 3.3Å; G334-R338 WeakPolarHBondContact O-CG 3.1Å; G334-R338 PolarHBondContact O-NH1 3.39Å
335Y95.3Very high94.3Very high104 Ų10451.6 Ų51.641%0.40827%0.27SS..THydrogen-bonded Turntrans-90.7-56.2-172.1-179.8-103.6000112.4I331 R337 R338 I339 F380 I384I331-Y335 CarbonylContact O-C 3.57Å; I331-Y335 WeakPolarHBondContact O-CA 3.37Å; I331-Y335 WeakPolarHBondContact O-CB 3.44Å; I331-Y335 PolarHBondContact O-N 2.94Å; Y335-R337 VanDerWaalsContact C-N 3.33Å; Y335-R337 PolarHBondContact O-N 3.47Å; Y335-R338 PolarHBondContact O-N 3.43Å; Y335-I339 HydrophobicContact CD1-CD1 4.39Å; Y335-I339 HydrophobicContact CE1-CD1 4.05Å; Y335-I339 HydrophobicContact CE1-CG1 4.29Å; Y335-I339 PolarHBondContact O-N 3.36Å; Y335-F380 HydrophobicContact CD1-CZ 4.35Å; Y335-F380 HydrophobicContact CE1-CZ 4.44Å; Y335-I384 HydrophobicContact CD1-CD1 3.8Å; Y335-I384 HydrophobicContact CD1-CG1 4.1Å; Y335-I384 HydrophobicContact CE1-CD1 3.66Å; Y335-I384 HydrophobicContact CE1-CG1 4.27Å
336A93.6Very high94.3Very high5 Ų557.6 Ų57.64%0.04129%0.29CS..G310 helixtrans-61.2-41.1-171.400000112.3A178 I331 R338 I339A178-A336 HydrophobicContact CB-CB 4.4Å; I331-A336 PolarHBondContact O-N 3.44Å; A336-R338 PolarHBondContact O-N 2.83Å; A336-I339 HydrophobicContact CB-CD1 4.43Å; A336-I339 WeakPolarHBondContact O-CB 3.49Å; A336-I339 WeakPolarHBondContact O-CG1 3.39Å; A336-I339 PolarHBondContact O-N 3.36Å
337R92.3Very high94.3Very high99 Ų9955.1 Ų55.137%0.37428%0.279SS..G310 helixtrans-59.9-24175173.8172.4164.5-177.9-7.6114.1K175 A178 M179 Q332 Y335K175-R337 HydrophobicContact CB-CG 4.39Å; K175-R337 VanDerWaalsContact CE-CZ 3.48Å; K175-R337 HydrophobicContact CG-CG 3.94Å; A178-R337 HydrophobicContact CB-CB 3.79Å; M179-R337 PolarHBondContact SD-NH1 2.92Å; M179-R337 VanDerWaalsContact SD-NH1 3.41Å; Q332-R337 WeakPolarHBondContact O-CB 3.45Å; Q332-R337 PolarHBondContact O-N 3.25Å; Y335-R337 VanDerWaalsContact C-N 3.33Å; Y335-R337 PolarHBondContact O-N 3.47Å
338R92.9Very high94.2Very high191 Ų19154.1 Ų54.172%0.72127%0.273SS*.G310 helixtrans-98.10.3-177.3-64.5-175.8-179.5116.2-6.5113.2G334 Y335 A336 K340G334-R338 VanDerWaalsContact O-CD 3.22Å; G334-R338 WeakPolarHBondContact O-CD 3.38Å; G334-R338 VanDerWaalsContact O-CG 3.3Å; G334-R338 WeakPolarHBondContact O-CG 3.1Å; G334-R338 PolarHBondContact O-NH1 3.39Å; Y335-R338 PolarHBondContact O-N 3.43Å; A336-R338 PolarHBondContact O-N 2.83Å; R338-K340 PolarHBondContact O-N 3.15Å
339I93.4Very high94.2Very high20 Ų2055.6 Ų55.610%0.10328%0.279CS..PPolyproline II helixtrans-63.4124.5175.2-65.2170.4000108.9Y335 A336 N343 E344 A347 I384 C388Y335-I339 HydrophobicContact CD1-CD1 4.39Å; Y335-I339 HydrophobicContact CE1-CD1 4.05Å; Y335-I339 HydrophobicContact CE1-CG1 4.29Å; Y335-I339 PolarHBondContact O-N 3.36Å; A336-I339 HydrophobicContact CB-CD1 4.43Å; A336-I339 WeakPolarHBondContact O-CB 3.49Å; A336-I339 WeakPolarHBondContact O-CG1 3.39Å; A336-I339 PolarHBondContact O-N 3.36Å; I339-N343 HydrophobicContact CG2-CB 4.22Å; I339-E344 HydrophobicContact CG2-CG 4.34Å; I339-A347 HydrophobicContact CD1-CB 3.72Å; I339-A347 HydrophobicContact CG2-CB 4.46Å; I339-I384 HydrophobicContact CD1-CG2 4.2Å; I339-C388 VanDerWaalsContact CD1-SG 3.53Å
340K91.4Very high94.2Very high154 Ų15463.1 Ų63.167%0.6731%0.305SS*.PPolyproline II helixtrans-69.7141-179.8-64.9-176.4-179.6-179.30110.5R338 G342 N343R338-K340 PolarHBondContact O-N 3.15Å; K340-G342 PolarHBondContact O-N 3Å; K340-N343 WeakPolarHBondContact O-CB 3.46Å; K340-N343 PolarHBondContact O-N 3.01Å; K340-N343 VanDerWaalsContact O-N 3.07Å
341P89.5Confident94.2Very high59 Ų5958.7 Ų58.738%0.38328%0.278SS..THydrogen-bonded Turntrans-52.8134.1172.9-27.335.5000113.1P170 K171 E344P170-P341 HydrophobicContact CB-CB 3.89Å; P170-P341 HydrophobicContact CB-CG 4.08Å; K171-P341 HydrophobicContact CB-CG 4.02Å; P341-E344 WeakPolarHBondContact CA-OE1 3.28Å
342G88.1Confident94.2Very high43 Ų4357.3 Ų57.344%0.44327%0.271SS..THydrogen-bonded Turntrans96-17.5-173.300000114.4K340 E344 Q456K340-G342 PolarHBondContact O-N 3Å; G342-E344 WeakPolarHBondContact CA-OE2 3.43Å; G342-E344 PolarHBondContact N-OE2 3.24Å; G342-Q456 PolarHBondContact O-NE2 3.34Å
343N93.6Very high94.3Very high60 Ų6060.9 Ų60.932%0.32129%0.289SS..  trans-98.8-1.1178.9-70.6-44.3000113.6I339 K340 I345 R346 A347I339-N343 HydrophobicContact CG2-CB 4.22Å; K340-N343 WeakPolarHBondContact O-CB 3.46Å; K340-N343 PolarHBondContact O-N 3.01Å; K340-N343 VanDerWaalsContact O-N 3.07Å; N343-I345 PolarHBondContact O-N 3.25Å; N343-R346 WeakPolarHBondContact O-CB 3.43Å; N343-R346 PolarHBondContact O-N 3.04Å; N343-A347 PolarHBondContact O-N 3.46Å
344E94.1Very high94.5Very high14 Ų1461.9 Ų61.97%0.06529%0.287CS..Hα-helixtrans-58.4-49.6-176-65.990.3163.200111.8S174 I339 P341 G342 R346 A347 V348 C388 V392S174-E344 PolarHBondContact OG-OE1 3.37Å; I339-E344 HydrophobicContact CG2-CG 4.34Å; P341-E344 WeakPolarHBondContact CA-OE1 3.28Å; G342-E344 WeakPolarHBondContact CA-OE2 3.43Å; G342-E344 PolarHBondContact N-OE2 3.24Å; E344-R346 VanDerWaalsContact C-N 3.27Å; E344-R346 PolarHBondContact O-N 3.45Å; E344-A347 WeakPolarHBondContact O-CB 3.35Å; E344-A347 PolarHBondContact O-N 2.96Å; E344-A347 VanDerWaalsContact O-N 3.1Å; E344-V348 VanDerWaalsContact O-CG2 3.3Å; E344-V348 WeakPolarHBondContact O-CG2 3.43Å; E344-V348 PolarHBondContact O-N 3.19Å; E344-C388 HydrophobicContact CB-CB 3.96Å; E344-C388 HydrophobicContact CG-CB 4.4Å; E344-V392 HydrophobicContact CB-CG2 3.49Å; E344-V392 VanDerWaalsContact CB-CG2 3.49Å; E344-V392 HydrophobicContact CG-CG2 4.13Å
345I94.8Very high94.6Very high24 Ų2460.9 Ų60.912%0.12328%0.277CS..Hα-helixtrans-61-38.2179-61.2-61000111.5L284 N343 V348 K349 L389 V392 L451L284-I345 HydrophobicContact CD2-CD1 3.68Å; N343-I345 PolarHBondContact O-N 3.25Å; I345-V348 PolarHBondContact O-N 3.19Å; I345-K349 HydrophobicContact CG2-CD 4.44Å; I345-K349 WeakPolarHBondContact O-CG 3.36Å; I345-K349 PolarHBondContact O-N 3.21Å; I345-L389 HydrophobicContact CD1-CD2 4.39Å; I345-V392 HydrophobicContact CD1-CB 4.33Å; I345-V392 HydrophobicContact CD1-CG1 4.12Å; I345-V392 HydrophobicContact CD1-CG2 3.93Å; I345-V392 HydrophobicContact CG1-CG1 4.47Å; I345-V392 HydrophobicContact CG1-CG2 4.11Å; I345-L451 HydrophobicContact CD1-CD2 4.24Å; I345-L451 HydrophobicContact CG2-CB 4.4Å
346R95.4Very high94.7Very high134 Ų13457 Ų5751%0.50626%0.263SS..Hα-helixtrans-65.2-41.5176.3-173.3-179.4-65.3163.8-0.6111.3N343 E344 K349 R350N343-R346 WeakPolarHBondContact O-CB 3.43Å; N343-R346 PolarHBondContact O-N 3.04Å; E344-R346 VanDerWaalsContact C-N 3.27Å; E344-R346 PolarHBondContact O-N 3.45Å; R346-K349 PolarHBondContact O-N 2.75Å; R346-R350 WeakPolarHBondContact O-CG 3.4Å; R346-R350 PolarHBondContact O-N 3.07Å; R346-R350 VanDerWaalsContact O-N 3.13Å
347A96.5Very high94.9Very high10 Ų1059.4 Ų59.48%0.08328%0.278CS..Hα-helixtrans-65-42.9175.700000111.6I339 N343 E344 R350 A351 I384I339-A347 HydrophobicContact CD1-CB 3.72Å; I339-A347 HydrophobicContact CG2-CB 4.46Å; N343-A347 PolarHBondContact O-N 3.46Å; E344-A347 WeakPolarHBondContact O-CB 3.35Å; E344-A347 PolarHBondContact O-N 2.96Å; E344-A347 VanDerWaalsContact O-N 3.1Å; A347-R350 PolarHBondContact O-N 3.04Å; A347-A351 WeakPolarHBondContact O-CB 3.2Å; A347-A351 PolarHBondContact O-N 3.44Å; A347-I384 HydrophobicContact CB-CG2 3.97Å
348V97.3Very high95.1Very high0 Ų054.7 Ų54.70%026%0.261CS..Hα-helixtrans-60-47.9175.2174.70000110.9E344 I345 R350 A351 I352 V385 C388 L389 L451E344-V348 VanDerWaalsContact O-CG2 3.3Å; E344-V348 WeakPolarHBondContact O-CG2 3.43Å; E344-V348 PolarHBondContact O-N 3.19Å; I345-V348 PolarHBondContact O-N 3.19Å; V348-R350 VanDerWaalsContact C-N 3.3Å; V348-R350 PolarHBondContact O-N 3.04Å; V348-A351 PolarHBondContact O-N 3.41Å; V348-A351 VanDerWaalsContact O-N 3.16Å; V348-I352 HydrophobicContact CG1-CD1 3.69Å; V348-I352 HydrophobicContact CG1-CG1 4.21Å; V348-I352 WeakPolarHBondContact O-CG1 3.47Å; V348-I352 PolarHBondContact O-N 2.82Å; V348-V385 HydrophobicContact CG1-CG1 4.04Å; V348-V385 HydrophobicContact CG1-CG2 4.4Å; V348-C388 HydrophobicContact CG2-CB 3.37Å; V348-L389 HydrophobicContact CG1-CD1 4.39Å; V348-L389 HydrophobicContact CG1-CD2 4.09Å; V348-L389 HydrophobicContact CG1-CG 4.11Å; V348-L389 HydrophobicContact CG2-CD2 4.2Å; V348-L389 HydrophobicContact CG2-CG 4.04Å; V348-L451 HydrophobicContact CB-CD1 4.36Å; V348-L451 HydrophobicContact CG1-CD1 3.45Å; V348-L451 VanDerWaalsContact CG1-CD1 3.45Å
349K97Very high95.3Very high57 Ų5745.7 Ų45.725%0.24823%0.227CC..Hα-helixtrans-58.7-41.7178-74.9-172.672.8168.60112.1I345 R346 M353 F448 L451I345-K349 HydrophobicContact CG2-CD 4.44Å; I345-K349 WeakPolarHBondContact O-CG 3.36Å; I345-K349 PolarHBondContact O-N 3.21Å; R346-K349 PolarHBondContact O-N 2.75Å; K349-M353 WeakPolarHBondContact O-CG 3.43Å; K349-M353 PolarHBondContact O-N 3.22Å; K349-F448 HydrophobicContact CB-CD2 3.9Å; K349-F448 HydrophobicContact CB-CE2 3.82Å; K349-F448 HydrophobicContact CD-CE2 4.42Å; K349-F448 HydrophobicContact CG-CD2 4.11Å; K349-F448 HydrophobicContact CG-CE2 4.27Å; K349-L451 HydrophobicContact CD-CB 4.32Å; K349-L451 HydrophobicContact CG-CB 4.08Å; K349-L451 HydrophobicContact CG-CD1 4.46Å
350R97.1Very high95.5Very high170 Ų17047.7 Ų47.764%0.64224%0.237SC*.Hα-helixtrans-65.1-42.6175.2-71.9177.3178.8-174.4-2.1112.2R346 A347 V348 M353 L354R346-R350 WeakPolarHBondContact O-CG 3.4Å; R346-R350 PolarHBondContact O-N 3.07Å; R346-R350 VanDerWaalsContact O-N 3.13Å; A347-R350 PolarHBondContact O-N 3.04Å; V348-R350 VanDerWaalsContact C-N 3.3Å; V348-R350 PolarHBondContact O-N 3.04Å; R350-M353 PolarHBondContact O-N 2.92Å; R350-L354 PolarHBondContact O-N 3.41Å
351A97.4Very high95.8Very high3 Ų342.7 Ų42.73%0.02522%0.217CC..Hα-helixtrans-63.4-43.917700000111.8A347 V348 M353 L354 L355 A381 I384 V385A347-A351 WeakPolarHBondContact O-CB 3.2Å; A347-A351 PolarHBondContact O-N 3.44Å; V348-A351 PolarHBondContact O-N 3.41Å; V348-A351 VanDerWaalsContact O-N 3.16Å; A351-M353 VanDerWaalsContact C-N 3.34Å; A351-M353 PolarHBondContact O-N 3.25Å; A351-L354 WeakPolarHBondContact O-CB 3.23Å; A351-L354 PolarHBondContact O-N 3.23Å; A351-L354 VanDerWaalsContact O-N 3.07Å; A351-L355 PolarHBondContact O-N 3.45Å; A351-L355 VanDerWaalsContact O-N 3.07Å; A351-A381 HydrophobicContact CB-CB 4.1Å; A351-A381 VanDerWaalsContact O-CB 3.25Å; A351-A381 WeakPolarHBondContact O-CB 3.34Å; A351-I384 HydrophobicContact CB-CB 4.03Å; A351-I384 HydrophobicContact CB-CD1 4.39Å; A351-I384 HydrophobicContact CB-CG2 4.14Å; A351-V385 HydrophobicContact CB-CG2 3.72Å
352I96.5Very high96.2Very high1 Ų140 Ų401%0.00520%0.2CC..Hα-helixtrans-61.5-42.6176.2-68.5173.9000111.1Y291 V348 L354 L355 V385 F444 P447 F448 L451Y291-I352 HydrophobicContact CD2-CG1 4.5Å; V348-I352 HydrophobicContact CG1-CD1 3.69Å; V348-I352 HydrophobicContact CG1-CG1 4.21Å; V348-I352 WeakPolarHBondContact O-CG1 3.47Å; V348-I352 PolarHBondContact O-N 2.82Å; I352-L354 PolarHBondContact O-N 3.46Å; I352-L355 WeakPolarHBondContact O-CB 3.42Å; I352-L355 PolarHBondContact O-N 3.16Å; I352-L355 VanDerWaalsContact O-N 3.14Å; I352-V385 HydrophobicContact CG1-CG2 4.16Å; I352-F444 HydrophobicContact CG2-CB 3.98Å; I352-F444 WeakPolarHBondContact CG2-O 3.48Å; I352-P447 HydrophobicContact CD1-CB 4.18Å; I352-P447 HydrophobicContact CD1-CG 4.38Å; I352-F448 HydrophobicContact CG2-CB 3.88Å; I352-L451 HydrophobicContact CD1-CD1 3.76Å
353M96.9Very high96.6Very high83 Ų8337.9 Ų37.941%0.40918%0.178SC..Hα-helixtrans-62.6-30.8174.6-72.8-59.5-61.100112.9K349 R350 A351 I356 P357 L445 F448K349-M353 WeakPolarHBondContact O-CG 3.43Å; K349-M353 PolarHBondContact O-N 3.22Å; R350-M353 PolarHBondContact O-N 2.92Å; A351-M353 VanDerWaalsContact C-N 3.34Å; A351-M353 PolarHBondContact O-N 3.25Å; M353-I356 HydrophobicContact CE-CD1 4.39Å; M353-I356 HydrophobicContact SD-CD1 4.11Å; M353-P357 WeakPolarHBondContact O-CD 3.45Å; M353-L445 HydrophobicContact SD-CD2 4.08Å; M353-F448 HydrophobicContact CG-CD2 3.61Å; M353-F448 HydrophobicContact CG-CE2 3.4Å; M353-F448 HydrophobicContact CG-CG 4.46Å; M353-F448 HydrophobicContact CG-CZ 4.13Å; M353-F448 HydrophobicContact SD-CD1 4.33Å; M353-F448 HydrophobicContact SD-CD2 3.81Å; M353-F448 HydrophobicContact SD-CE1 4.32Å; M353-F448 HydrophobicContact SD-CE2 3.78Å; M353-F448 HydrophobicContact SD-CG 4.08Å; M353-F448 HydrophobicContact SD-CZ 4.05Å
354L97.5Very high96.8Very high48 Ų4842 Ų4225%0.25119%0.19SC..Hα-helixtrans-74.8-26176.2-16865.5000112.8R350 A351 I352 I356 P357 A358 L377 F380 A381R350-L354 PolarHBondContact O-N 3.41Å; A351-L354 WeakPolarHBondContact O-CB 3.23Å; A351-L354 PolarHBondContact O-N 3.23Å; A351-L354 VanDerWaalsContact O-N 3.07Å; I352-L354 PolarHBondContact O-N 3.46Å; L354-I356 VanDerWaalsContact C-N 3.3Å; L354-I356 PolarHBondContact O-N 3.09Å; L354-P357 VanDerWaalsContact O-CD 3.32Å; L354-P357 WeakPolarHBondContact O-CD 3.41Å; L354-P357 WeakPolarHBondContact O-CG 3.15Å; L354-A358 WeakPolarHBondContact O-CB 3.41Å; L354-A358 PolarHBondContact O-N 3.33Å; L354-L377 HydrophobicContact CD1-CD1 4.43Å; L354-L377 HydrophobicContact CD1-CD2 4.1Å; L354-L377 HydrophobicContact CD2-CD2 4.44Å; L354-L377 HydrophobicContact CG-CB 4.34Å; L354-L377 HydrophobicContact CG-CD2 4.47Å; L354-F380 HydrophobicContact CD2-CB 4.35Å; L354-F380 HydrophobicContact CD2-CD1 3.64Å; L354-F380 HydrophobicContact CD2-CE1 4.41Å; L354-F380 HydrophobicContact CD2-CG 4.33Å; L354-A381 HydrophobicContact CB-CB 4.3Å; L354-A381 HydrophobicContact CD2-CB 4.4Å
355L96.9Very high97Very high0 Ų041.4 Ų41.40%019%0.187CC..Hα-helixtrans-67.4-30.6176.9-73.7171000113.1Y291 A351 I352 A358 F359 Y378 A381 F444Y291-L355 HydrophobicContact CD2-CD1 4.33Å; Y291-L355 HydrophobicContact CE2-CD1 3.6Å; A351-L355 PolarHBondContact O-N 3.45Å; A351-L355 VanDerWaalsContact O-N 3.07Å; I352-L355 WeakPolarHBondContact O-CB 3.42Å; I352-L355 PolarHBondContact O-N 3.16Å; I352-L355 VanDerWaalsContact O-N 3.14Å; L355-A358 WeakPolarHBondContact O-CB 3.47Å; L355-A358 PolarHBondContact O-N 3.33Å; L355-F359 HydrophobicContact CB-CD2 4.15Å; L355-F359 HydrophobicContact CB-CE2 4.15Å; L355-F359 HydrophobicContact CD2-CD2 4.48Å; L355-F359 HydrophobicContact CD2-CE2 3.89Å; L355-F359 HydrophobicContact CD2-CZ 4.49Å; L355-F359 HydrophobicContact CG-CE2 4.44Å; L355-F359 VanDerWaalsContact O-CD2 3.25Å; L355-F359 WeakPolarHBondContact O-CD2 3.17Å; L355-F359 PolarHBondContact O-N 3.47Å; L355-Y378 HydrophobicContact CD2-CD2 4.15Å; L355-A381 HydrophobicContact CD1-CB 4.32Å; L355-A381 HydrophobicContact CD2-CB 3.56Å; L355-A381 HydrophobicContact CG-CB 3.56Å; L355-F444 HydrophobicContact CB-CG 4.49Å; L355-F444 HydrophobicContact CD1-CD1 4.06Å; L355-F444 HydrophobicContact CD1-CE1 3.87Å; L355-F444 HydrophobicContact CD1-CZ 4.27Å
356I96.1Very high97Very high23 Ų2344.3 Ų44.312%0.11821%0.214CC..Hα-helixtrans-59.5-60.2179.6-57169.7000110.5M353 L354 A358 F359 L360 F444 L445M353-I356 HydrophobicContact CE-CD1 4.39Å; M353-I356 HydrophobicContact SD-CD1 4.11Å; L354-I356 VanDerWaalsContact C-N 3.3Å; L354-I356 PolarHBondContact O-N 3.09Å; I356-A358 VanDerWaalsContact C-N 3.27Å; I356-A358 PolarHBondContact O-N 3.37Å; I356-F359 PolarHBondContact O-N 2.93Å; I356-L360 HydrophobicContact CG2-CD1 4.19Å; I356-L360 VanDerWaalsContact O-CG 3.3Å; I356-L360 WeakPolarHBondContact O-CG 3.4Å; I356-L360 PolarHBondContact O-N 3.46Å; I356-L360 VanDerWaalsContact O-N 3.08Å; I356-F444 HydrophobicContact CG1-CB 4.32Å; I356-L445 HydrophobicContact CD1-CD2 3.53Å; I356-L445 HydrophobicContact CD1-CG 3.76Å
357P97.4Very high97Very high55 Ų5541.9 Ų41.936%0.35721%0.211SC..Hα-helixtrans-64.4-30.6175.626.6-34000112.5M353 L354 L360 L361M353-P357 WeakPolarHBondContact O-CD 3.45Å; L354-P357 VanDerWaalsContact O-CD 3.32Å; L354-P357 WeakPolarHBondContact O-CD 3.41Å; L354-P357 WeakPolarHBondContact O-CG 3.15Å; P357-L360 PolarHBondContact O-N 3.44Å; P357-L361 WeakPolarHBondContact O-CB 3.26Å; P357-L361 VanDerWaalsContact O-CG 3.25Å; P357-L361 WeakPolarHBondContact O-CG 3.48Å; P357-L361 PolarHBondContact O-N 3.13Å
358A98.1Very high97Very high0 Ų044.8 Ų44.80%023%0.228CC..Hα-helixtrans-59.7-50.6176.200000112.1L354 L355 I356 L361 I362 L377L354-A358 WeakPolarHBondContact O-CB 3.41Å; L354-A358 PolarHBondContact O-N 3.33Å; L355-A358 WeakPolarHBondContact O-CB 3.47Å; L355-A358 PolarHBondContact O-N 3.33Å; I356-A358 VanDerWaalsContact C-N 3.27Å; I356-A358 PolarHBondContact O-N 3.37Å; A358-L361 PolarHBondContact O-N 2.83Å; A358-I362 WeakPolarHBondContact O-CD1 3.26Å; A358-I362 VanDerWaalsContact O-CG1 3.26Å; A358-I362 WeakPolarHBondContact O-CG1 3.44Å; A358-I362 PolarHBondContact O-N 3.13Å; A358-L377 HydrophobicContact CB-CB 3.67Å
359F97.3Very high96.9Very high2 Ų249.6 Ų49.61%0.00926%0.258CS..Hα-helixtrans-72.8-29.2179.7-74.2-59.2000113.2L298 L355 I356 I362 G363 Y378 F437 F444L298-F359 HydrophobicContact CB-CD1 4.03Å; L298-F359 HydrophobicContact CB-CE1 3.51Å; L298-F359 HydrophobicContact CB-CZ 3.89Å; L298-F359 HydrophobicContact CD1-CB 4.16Å; L298-F359 HydrophobicContact CD1-CD1 3.53Å; L298-F359 HydrophobicContact CD1-CD2 3.71Å; L298-F359 HydrophobicContact CD1-CE1 3.69Å; L298-F359 HydrophobicContact CD1-CE2 3.87Å; L298-F359 HydrophobicContact CD1-CG 3.53Å; L298-F359 HydrophobicContact CD1-CZ 3.84Å; L298-F359 HydrophobicContact CG-CD1 4.39Å; L298-F359 HydrophobicContact CG-CE1 4.26Å; L355-F359 HydrophobicContact CB-CD2 4.15Å; L355-F359 HydrophobicContact CB-CE2 4.15Å; L355-F359 HydrophobicContact CD2-CD2 4.48Å; L355-F359 HydrophobicContact CD2-CE2 3.89Å; L355-F359 HydrophobicContact CD2-CZ 4.49Å; L355-F359 HydrophobicContact CG-CE2 4.44Å; L355-F359 VanDerWaalsContact O-CD2 3.25Å; L355-F359 WeakPolarHBondContact O-CD2 3.17Å; L355-F359 PolarHBondContact O-N 3.47Å; I356-F359 PolarHBondContact O-N 2.93Å; F359-I362 HydrophobicContact CD1-CD1 4.06Å; F359-I362 HydrophobicContact CE1-CD1 4.45Å; F359-I362 PolarHBondContact O-N 3.49Å; F359-G363 PolarHBondContact O-N 3.41Å; F359-Y378 AromaticContact CE1-CD2 3.76Å; F359-Y378 HydrophobicContact CE1-CD2 3.76Å; F359-Y378 AromaticContact CE1-CE2 3.96Å; F359-Y378 HydrophobicContact CE1-CE2 3.96Å; F359-Y378 HydrophobicContact CE2-CD2 4.35Å; F359-Y378 AromaticContact CZ-CD2 3.56Å; F359-Y378 HydrophobicContact CZ-CD2 3.56Å; F359-Y378 AromaticContact CZ-CE2 3.66Å; F359-Y378 HydrophobicContact CZ-CE2 3.66Å; F359-F437 HydrophobicContact CB-CD1 4.41Å; F359-F437 AromaticContact CD1-CD1 3.94Å; F359-F437 HydrophobicContact CD1-CD1 3.94Å; F359-F437 HydrophobicContact CD1-CE1 4.03Å; F359-F444 HydrophobicContact CD2-CD2 4.13Å; F359-F444 AromaticContact CD2-CE2 3.63Å; F359-F444 HydrophobicContact CD2-CE2 3.63Å; F359-F444 HydrophobicContact CD2-CZ 4.43Å; F359-F444 HydrophobicContact CE2-CD2 4.18Å; F359-F444 AromaticContact CE2-CE2 3.32Å; F359-F444 HydrophobicContact CE2-CE2 3.32Å; F359-F444 AromaticContact CE2-CZ 3.68Å; F359-F444 HydrophobicContact CE2-CZ 3.68Å; F359-F444 HydrophobicContact CZ-CE2 4.31Å; F359-F444 HydrophobicContact CZ-CZ 4.46Å
360L96.8Very high96.9Very high61 Ų6149.5 Ų49.532%0.31926%0.259SS..Hα-helixtrans-63.9-45.9169.4-68.5173.3000111.2I356 P357 I362 G363 W364 T438I356-L360 HydrophobicContact CG2-CD1 4.19Å; I356-L360 VanDerWaalsContact O-CG 3.3Å; I356-L360 WeakPolarHBondContact O-CG 3.4Å; I356-L360 PolarHBondContact O-N 3.46Å; I356-L360 VanDerWaalsContact O-N 3.08Å; P357-L360 PolarHBondContact O-N 3.44Å; L360-I362 VanDerWaalsContact C-N 3.34Å; L360-I362 PolarHBondContact O-N 3.2Å; L360-G363 PolarHBondContact O-N 3.43Å; L360-W364 WeakPolarHBondContact O-CB 3.5Å; L360-W364 VanDerWaalsContact O-CD1 3.31Å; L360-W364 PolarHBondContact O-N 3.18Å; L360-T438 HydrophobicContact CD2-CG2 3.88Å
361L97.8Very high96.9Very high49 Ų4941.5 Ų41.526%0.25723%0.229SC..Hα-helixtrans-61.2-41.6175.9-73.1174.4000112P357 A358 A365 M370 V373 L377P357-L361 WeakPolarHBondContact O-CB 3.26Å; P357-L361 VanDerWaalsContact O-CG 3.25Å; P357-L361 WeakPolarHBondContact O-CG 3.48Å; P357-L361 PolarHBondContact O-N 3.13Å; A358-L361 PolarHBondContact O-N 2.83Å; L361-A365 VanDerWaalsContact O-CA 3.31Å; L361-A365 WeakPolarHBondContact O-CA 3.5Å; L361-A365 VanDerWaalsContact O-CB 3.29Å; L361-A365 WeakPolarHBondContact O-CB 3.2Å; L361-A365 PolarHBondContact O-N 3.1Å; L361-M370 HydrophobicContact CD2-CE 3.81Å; L361-M370 HydrophobicContact CD2-CG 4.17Å; L361-V373 HydrophobicContact CD1-CG1 3.99Å; L361-L377 HydrophobicContact CD1-CD1 3.98Å
362I97.9Very high96.9Very high2 Ų243.8 Ų43.81%0.0124%0.244CC..Hα-helixtrans-66-50.7176.7-67.1163.2000110.6L302 L305 A358 F359 L360 W364 A365 L371 L375 F437L302-I362 HydrophobicContact CD1-CG2 3.6Å; L305-I362 HydrophobicContact CD1-CG2 4.22Å; A358-I362 WeakPolarHBondContact O-CD1 3.26Å; A358-I362 VanDerWaalsContact O-CG1 3.26Å; A358-I362 WeakPolarHBondContact O-CG1 3.44Å; A358-I362 PolarHBondContact O-N 3.13Å; F359-I362 HydrophobicContact CD1-CD1 4.06Å; F359-I362 HydrophobicContact CE1-CD1 4.45Å; F359-I362 PolarHBondContact O-N 3.49Å; L360-I362 VanDerWaalsContact C-N 3.34Å; L360-I362 PolarHBondContact O-N 3.2Å; I362-W364 VanDerWaalsContact C-N 3.27Å; I362-W364 PolarHBondContact O-N 2.92Å; I362-A365 WeakPolarHBondContact O-CB 3.38Å; I362-A365 PolarHBondContact O-N 3.43Å; I362-L371 HydrophobicContact CB-CD1 4.49Å; I362-L371 HydrophobicContact CG1-CD1 4.33Å; I362-L371 HydrophobicContact CG2-CD1 4.05Å; I362-L375 HydrophobicContact CD1-CD2 3.91Å; I362-L375 HydrophobicContact CG1-CD2 4.27Å; I362-F437 HydrophobicContact CB-CD1 4.26Å; I362-F437 HydrophobicContact CB-CE1 4.28Å; I362-F437 HydrophobicContact CG2-CD1 3.86Å; I362-F437 HydrophobicContact CG2-CE1 3.45Å; I362-F437 VanDerWaalsContact CG2-CE1 3.45Å; I362-F437 HydrophobicContact CG2-CZ 4.16Å
363G97.1Very high97Very high0 Ų047.1 Ų47.10%026%0.264CS..Hα-helixtrans-60.2-35.1-177.900000113.2R309 F359 L360 F437R309-G363 VanDerWaalsContact CZ-O 3.26Å; R309-G363 PolarHBondContact NH1-O 2.97Å; R309-G363 PolarHBondContact NH2-O 2.9Å; F359-G363 PolarHBondContact O-N 3.41Å; L360-G363 PolarHBondContact O-N 3.43Å; G363-F437 VanDerWaalsContact CA-CB 3.48Å
364W97.6Very high97Very high147 Ų14743.1 Ų43.156%0.55725%0.245SC*.THydrogen-bonded Turntrans-105.911.5-179.1-67.184.9000113.8L360 I362 A366 M370 E434 T438L360-W364 WeakPolarHBondContact O-CB 3.5Å; L360-W364 VanDerWaalsContact O-CD1 3.31Å; L360-W364 PolarHBondContact O-N 3.18Å; I362-W364 VanDerWaalsContact C-N 3.27Å; I362-W364 PolarHBondContact O-N 2.92Å; W364-A366 PolarHBondContact O-N 3.25Å; W364-M370 HydrophobicContact CB-CE 4.03Å; W364-M370 WeakPolarHBondContact O-CE 3.43Å; W364-E434 HydrophobicContact CD2-CB 4.37Å; W364-E434 HydrophobicContact CD2-CG 4.15Å; W364-E434 HydrophobicContact CE3-CG 4.15Å; W364-E434 HydrophobicContact CH2-CB 4.28Å; W364-E434 HydrophobicContact CH2-CG 4.37Å; W364-E434 HydrophobicContact CZ2-CB 3.91Å; W364-E434 HydrophobicContact CZ2-CG 4.36Å; W364-E434 HydrophobicContact CZ3-CG 4.26Å; W364-T438 PolarHBondContact NE1-OG1 2.85Å
365A97.2Very high97Very high0 Ų041 Ų410%023%0.234CC..  trans-57.2115.7-177.700000111.4R309 F310 L361 I362 M370 L371R309-A365 WeakPolarHBondContact CD-O 3.37Å; R309-A365 VanDerWaalsContact NH1-N 3.16Å; R309-A365 PolarHBondContact NH1-O 2.68Å; F310-A365 HydrophobicContact CE2-CB 4.13Å; F310-A365 HydrophobicContact CZ-CB 3.74Å; F310-A365 WeakPolarHBondContact CZ-O 3.48Å; L361-A365 VanDerWaalsContact O-CA 3.31Å; L361-A365 WeakPolarHBondContact O-CA 3.5Å; L361-A365 VanDerWaalsContact O-CB 3.29Å; L361-A365 WeakPolarHBondContact O-CB 3.2Å; L361-A365 PolarHBondContact O-N 3.1Å; I362-A365 WeakPolarHBondContact O-CB 3.38Å; I362-A365 PolarHBondContact O-N 3.43Å; A365-M370 HydrophobicContact CB-CB 4.42Å; A365-M370 HydrophobicContact CB-CG 4.33Å; A365-L371 HydrophobicContact CB-CB 3.87Å; A365-L371 HydrophobicContact CB-CD1 4.45Å
366A95.4Very high97.1Very high85 Ų8545.1 Ų45.170%0.70226%0.255SS*.  trans-90.5-19.9176.300000113W364W364-A366 PolarHBondContact O-N 3.25Å
367N96Very high97.2Very high83 Ų8346.2 Ų46.244%0.44426%0.261SS..SBendtrans-144.5165.7178.957.854.4000110.4T369 M370 L371N367-T369 PolarHBondContact O-N 3.45Å; N367-T369 WeakPolarHBondContact OD1-CB 3.41Å; N367-T369 PolarHBondContact OD1-N 3.48Å; N367-M370 PolarHBondContact O-N 3.07Å; N367-M370 WeakPolarHBondContact OD1-CB 3.32Å; N367-M370 PolarHBondContact OD1-N 3.43Å; N367-L371 PolarHBondContact O-N 3.06Å; N367-L371 VanDerWaalsContact O-N 3.16Å
368V95.1Very high97.2Very high71 Ų7143.7 Ų43.743%0.4324%0.244SC..Hα-helixtrans-61.8-33.3-177.8179.60000111.5F310 F312 L371 S372F310-V368 HydrophobicContact CD1-CG2 4.14Å; F312-V368 HydrophobicContact CE1-CG2 4.2Å; F312-V368 HydrophobicContact CZ-CG1 4.4Å; F312-V368 HydrophobicContact CZ-CG2 4.3Å; V368-L371 WeakPolarHBondContact O-CB 3.26Å; V368-L371 PolarHBondContact O-N 3.13Å; V368-S372 WeakPolarHBondContact O-CB 3.38Å; V368-S372 PolarHBondContact O-N 3.27Å; V368-S372 PolarHBondContact O-OG 2.8Å
369T95.8Very high97.1Very high102 Ų10243.7 Ų43.763%0.62624%0.244SC*.Hα-helixtrans-63-47.3178.3-50.30000111.8N367 L371 S372 V373N367-T369 PolarHBondContact O-N 3.45Å; N367-T369 WeakPolarHBondContact OD1-CB 3.41Å; N367-T369 PolarHBondContact OD1-N 3.48Å; T369-L371 VanDerWaalsContact C-N 3.32Å; T369-L371 PolarHBondContact O-N 3.2Å; T369-S372 PolarHBondContact O-N 2.92Å; T369-V373 WeakPolarHBondContact O-CG2 3.35Å; T369-V373 PolarHBondContact O-N 3.35Å
370M97.5Very high97.1Very high55 Ų5547.2 Ų47.227%0.27126%0.26SS..Hα-helixtrans-62.1-41.2176.7-175.1174170.700111.3L361 W364 A365 N367 V373 G374L361-M370 HydrophobicContact CD2-CE 3.81Å; L361-M370 HydrophobicContact CD2-CG 4.17Å; W364-M370 HydrophobicContact CB-CE 4.03Å; W364-M370 WeakPolarHBondContact O-CE 3.43Å; A365-M370 HydrophobicContact CB-CB 4.42Å; A365-M370 HydrophobicContact CB-CG 4.33Å; N367-M370 PolarHBondContact O-N 3.07Å; N367-M370 WeakPolarHBondContact OD1-CB 3.32Å; N367-M370 PolarHBondContact OD1-N 3.43Å; M370-V373 PolarHBondContact O-N 3.31Å; M370-G374 PolarHBondContact O-N 3.18Å
371L97.6Very high97.1Very high2 Ų244.3 Ų44.31%0.0125%0.245CC..Hα-helixtrans-58.9-50.1172.2177.966.3000110.9L302 T306 F310 F312 I362 A365 N367 V368 T369 V373 G374 L375L302-L371 HydrophobicContact CD1-CD1 4.4Å; T306-L371 HydrophobicContact CG2-CD2 4.01Å; F310-L371 HydrophobicContact CD2-CD2 4.01Å; F310-L371 HydrophobicContact CE2-CB 4.32Å; F310-L371 HydrophobicContact CE2-CD2 3.87Å; F310-L371 HydrophobicContact CE2-CG 4.49Å; F310-L371 HydrophobicContact CZ-CB 4.34Å; F312-L371 HydrophobicContact CE2-CD2 4.26Å; F312-L371 HydrophobicContact CZ-CD2 4.29Å; I362-L371 HydrophobicContact CB-CD1 4.49Å; I362-L371 HydrophobicContact CG1-CD1 4.33Å; I362-L371 HydrophobicContact CG2-CD1 4.05Å; A365-L371 HydrophobicContact CB-CB 3.87Å; A365-L371 HydrophobicContact CB-CD1 4.45Å; N367-L371 PolarHBondContact O-N 3.06Å; N367-L371 VanDerWaalsContact O-N 3.16Å; V368-L371 WeakPolarHBondContact O-CB 3.26Å; V368-L371 PolarHBondContact O-N 3.13Å; T369-L371 VanDerWaalsContact C-N 3.32Å; T369-L371 PolarHBondContact O-N 3.2Å; L371-V373 VanDerWaalsContact C-N 3.34Å; L371-V373 PolarHBondContact O-N 3.2Å; L371-G374 PolarHBondContact O-N 2.89Å; L371-G374 VanDerWaalsContact O-N 3.15Å; L371-L375 HydrophobicContact CD1-CD1 4.28Å; L371-L375 HydrophobicContact CD1-CG 4.18Å; L371-L375 HydrophobicContact CG-CD1 3.99Å; L371-L375 HydrophobicContact CG-CG 4.27Å; L371-L375 VanDerWaalsContact O-CG 3.29Å; L371-L375 WeakPolarHBondContact O-CG 3.43Å; L371-L375 PolarHBondContact O-N 3.37Å
372S96.7Very high97Very high51 Ų5142 Ų4236%0.35723%0.233SC..Hα-helixtrans-60.9-38.9-179.1-64.80000113.1V368 T369 L375 L376V368-S372 WeakPolarHBondContact O-CB 3.38Å; V368-S372 PolarHBondContact O-N 3.27Å; V368-S372 PolarHBondContact O-OG 2.8Å; T369-S372 PolarHBondContact O-N 2.92Å; S372-L375 PolarHBondContact O-N 2.97Å; S372-L376 WeakPolarHBondContact O-CB 3.18Å; S372-L376 PolarHBondContact O-N 3Å
373V97.9Very high96.9Very high70 Ų7041.9 Ų41.942%0.42423%0.232SC..Hα-helixtrans-64.2-46.5173.7174.90000110.5L361 T369 M370 L371 L375 L376 L377L361-V373 HydrophobicContact CD1-CG1 3.99Å; T369-V373 WeakPolarHBondContact O-CG2 3.35Å; T369-V373 PolarHBondContact O-N 3.35Å; M370-V373 PolarHBondContact O-N 3.31Å; L371-V373 VanDerWaalsContact C-N 3.34Å; L371-V373 PolarHBondContact O-N 3.2Å; V373-L375 VanDerWaalsContact C-N 3.33Å; V373-L375 PolarHBondContact O-N 3.41Å; V373-L376 PolarHBondContact O-N 3.04Å; V373-L377 WeakPolarHBondContact O-CG 3.25Å; V373-L377 PolarHBondContact O-N 3.15Å; V373-L377 VanDerWaalsContact O-N 3.1Å
374G98Very high96.9Very high0 Ų042.1 Ų42.10%023%0.233CC..Hα-helixtrans-57.9-44.1175.100000112.5M370 L371 L377 Y378M370-G374 PolarHBondContact O-N 3.18Å; L371-G374 PolarHBondContact O-N 2.89Å; L371-G374 VanDerWaalsContact O-N 3.15Å; G374-L377 PolarHBondContact O-N 3.18Å; G374-Y378 VanDerWaalsContact O-CB 3.3Å; G374-Y378 WeakPolarHBondContact O-CB 3.36Å; G374-Y378 PolarHBondContact O-N 3.33Å
375L97.8Very high96.9Very high4 Ų435.1 Ų35.12%0.02121%0.207CC..Hα-helixtrans-64.9-37.9176.8-68179.2000112.9L302 M320 F323 I324 I362 L371 S372 V373 Y378 S379L302-L375 HydrophobicContact CD1-CD2 4.39Å; L302-L375 HydrophobicContact CD2-CD2 3.81Å; M320-L375 HydrophobicContact CG-CD1 3.45Å; M320-L375 VanDerWaalsContact CG-CD1 3.45Å; M320-L375 HydrophobicContact SD-CD1 3.74Å; F323-L375 HydrophobicContact CE1-CB 4.41Å; I324-L375 HydrophobicContact CD1-CD2 3.94Å; I324-L375 HydrophobicContact CG1-CD2 4.49Å; I362-L375 HydrophobicContact CD1-CD2 3.91Å; I362-L375 HydrophobicContact CG1-CD2 4.27Å; L371-L375 HydrophobicContact CD1-CD1 4.28Å; L371-L375 HydrophobicContact CD1-CG 4.18Å; L371-L375 HydrophobicContact CG-CD1 3.99Å; L371-L375 HydrophobicContact CG-CG 4.27Å; L371-L375 VanDerWaalsContact O-CG 3.29Å; L371-L375 WeakPolarHBondContact O-CG 3.43Å; L371-L375 PolarHBondContact O-N 3.37Å; S372-L375 PolarHBondContact O-N 2.97Å; V373-L375 VanDerWaalsContact C-N 3.33Å; V373-L375 PolarHBondContact O-N 3.41Å; L375-Y378 WeakPolarHBondContact O-CB 3.49Å; L375-Y378 PolarHBondContact O-N 3.06Å; L375-S379 WeakPolarHBondContact O-CB 3.29Å; L375-S379 PolarHBondContact O-N 3.21Å; L375-S379 PolarHBondContact O-OG 3.26Å; L375-S379 VanDerWaalsContact O-OG 3.06Å
376L98.1Very high96.8Very high85 Ų8537.1 Ų37.145%0.44522%0.217SC..Hα-helixtrans-62.3-46.3175.417965.4000111.3F323 T327 S372 V373 S379 F380F323-L376 HydrophobicContact CZ-CB 4.42Å; F323-L376 HydrophobicContact CZ-CD1 4.19Å; T327-L376 HydrophobicContact CG2-CD1 3.94Å; S372-L376 WeakPolarHBondContact O-CB 3.18Å; S372-L376 PolarHBondContact O-N 3Å; V373-L376 PolarHBondContact O-N 3.04Å; L376-S379 PolarHBondContact O-N 2.91Å; L376-F380 PolarHBondContact O-N 3.4Å
377L98.1Very high96.8Very high46 Ų4633.4 Ų33.424%0.24119%0.186CC..Hα-helixtrans-63.9-42.9176.3-63.6-173.7000111.5L354 A358 L361 V373 G374 F380 A381L354-L377 HydrophobicContact CD1-CD1 4.43Å; L354-L377 HydrophobicContact CD1-CD2 4.1Å; L354-L377 HydrophobicContact CD2-CD2 4.44Å; L354-L377 HydrophobicContact CG-CB 4.34Å; L354-L377 HydrophobicContact CG-CD2 4.47Å; A358-L377 HydrophobicContact CB-CB 3.67Å; L361-L377 HydrophobicContact CD1-CD1 3.98Å; V373-L377 WeakPolarHBondContact O-CG 3.25Å; V373-L377 PolarHBondContact O-N 3.15Å; V373-L377 VanDerWaalsContact O-N 3.1Å; G374-L377 PolarHBondContact O-N 3.18Å; L377-F380 PolarHBondContact O-N 2.85Å; L377-A381 PolarHBondContact O-N 3.24Å
378Y97.5Very high96.8Very high2 Ų229.7 Ų29.71%0.00817%0.166CC..Hα-helixtrans-56.3-52174.2162.4-93.8000111.2F295 E299 I324 L355 F359 G374 L375 F380 A381 A382F295-Y378 AromaticContact CD2-CE2 3.81Å; F295-Y378 HydrophobicContact CD2-CE2 3.81Å; F295-Y378 HydrophobicContact CE2-CD2 4.18Å; F295-Y378 AromaticContact CE2-CE2 3.2Å; F295-Y378 HydrophobicContact CE2-CE2 3.2Å; F295-Y378 AromaticContact CE2-CZ 3.43Å; F295-Y378 VanDerWaalsContact CE2-CZ 3.43Å; F295-Y378 VanDerWaalsContact CE2-OH 3.27Å; F295-Y378 WeakPolarHBondContact CE2-OH 3.39Å; F295-Y378 AromaticContact CZ-CE2 3.89Å; F295-Y378 HydrophobicContact CZ-CE2 3.89Å; F295-Y378 AromaticContact CZ-CZ 3.63Å; F295-Y378 WeakPolarHBondContact CZ-OH 3.12Å; E299-Y378 PolarHBondContact OE1-OH 3.4Å; I324-Y378 HydrophobicContact CD1-CE1 4.25Å; I324-Y378 HydrophobicContact CG2-CD1 4.3Å; I324-Y378 HydrophobicContact CG2-CE1 3.75Å; L355-Y378 HydrophobicContact CD2-CD2 4.15Å; F359-Y378 AromaticContact CE1-CD2 3.76Å; F359-Y378 HydrophobicContact CE1-CD2 3.76Å; F359-Y378 AromaticContact CE1-CE2 3.96Å; F359-Y378 HydrophobicContact CE1-CE2 3.96Å; F359-Y378 HydrophobicContact CE2-CD2 4.35Å; F359-Y378 AromaticContact CZ-CD2 3.56Å; F359-Y378 HydrophobicContact CZ-CD2 3.56Å; F359-Y378 AromaticContact CZ-CE2 3.66Å; F359-Y378 HydrophobicContact CZ-CE2 3.66Å; G374-Y378 VanDerWaalsContact O-CB 3.3Å; G374-Y378 WeakPolarHBondContact O-CB 3.36Å; G374-Y378 PolarHBondContact O-N 3.33Å; L375-Y378 WeakPolarHBondContact O-CB 3.49Å; L375-Y378 PolarHBondContact O-N 3.06Å; Y378-F380 VanDerWaalsContact C-N 3.33Å; Y378-F380 PolarHBondContact O-N 2.64Å; Y378-A381 PolarHBondContact O-N 3.38Å; Y378-A382 WeakPolarHBondContact O-CB 3.45Å; Y378-A382 PolarHBondContact O-N 3.03Å
379S97Very high96.9Very high0 Ų026.3 Ų26.30%015%0.146CC..Hα-helixtrans-60.6-41.5179.5-67.50000112.3I324 M328 L375 L376 A383I324-S379 WeakPolarHBondContact CA-OG 3.2Å; I324-S379 PolarHBondContact O-OG 3.36Å; M328-S379 WeakPolarHBondContact CG-O 3.49Å; L375-S379 WeakPolarHBondContact O-CB 3.29Å; L375-S379 PolarHBondContact O-N 3.21Å; L375-S379 PolarHBondContact O-OG 3.26Å; L375-S379 VanDerWaalsContact O-OG 3.06Å; L376-S379 PolarHBondContact O-N 2.91Å; S379-A383 WeakPolarHBondContact O-CB 3.5Å; S379-A383 PolarHBondContact O-N 3.36Å; S379-A383 VanDerWaalsContact O-N 3.08Å
380F96.9Very high96.9Very high76 Ų7621.9 Ų21.933%0.33312%0.119SC..Hα-helixtrans-62-46.3177.5-173.3-84.1000111.9I331 Y335 L354 L376 L377 Y378 I384I331-F380 HydrophobicContact CD1-CD2 3.57Å; I331-F380 HydrophobicContact CD1-CE2 3.78Å; I331-F380 HydrophobicContact CG1-CD2 3.84Å; I331-F380 HydrophobicContact CG1-CE2 4.41Å; I331-F380 HydrophobicContact CG2-CD2 4.07Å; I331-F380 HydrophobicContact CG2-CE2 4.21Å; Y335-F380 HydrophobicContact CD1-CZ 4.35Å; Y335-F380 HydrophobicContact CE1-CZ 4.44Å; L354-F380 HydrophobicContact CD2-CB 4.35Å; L354-F380 HydrophobicContact CD2-CD1 3.64Å; L354-F380 HydrophobicContact CD2-CE1 4.41Å; L354-F380 HydrophobicContact CD2-CG 4.33Å; L376-F380 PolarHBondContact O-N 3.4Å; L377-F380 PolarHBondContact O-N 2.85Å; Y378-F380 VanDerWaalsContact C-N 3.33Å; Y378-F380 PolarHBondContact O-N 2.64Å; F380-I384 HydrophobicContact CD1-CD1 3.91Å; F380-I384 HydrophobicContact CE1-CD1 3.51Å; F380-I384 HydrophobicContact CZ-CD1 4.12Å; F380-I384 WeakPolarHBondContact O-CD1 3.34Å
381A96.6Very high96.8Very high0 Ų019.6 Ų19.60%011%0.109CC..Hα-helixtrans-70.4-46.3-179.700000112.4A351 L354 L355 L377 Y378 A383 I384 V385A351-A381 HydrophobicContact CB-CB 4.1Å; A351-A381 VanDerWaalsContact O-CB 3.25Å; A351-A381 WeakPolarHBondContact O-CB 3.34Å; L354-A381 HydrophobicContact CB-CB 4.3Å; L354-A381 HydrophobicContact CD2-CB 4.4Å; L355-A381 HydrophobicContact CD1-CB 4.32Å; L355-A381 HydrophobicContact CD2-CB 3.56Å; L355-A381 HydrophobicContact CG-CB 3.56Å; L377-A381 PolarHBondContact O-N 3.24Å; Y378-A381 PolarHBondContact O-N 3.38Å; A381-A383 PolarHBondContact O-N 2.91Å; A381-I384 PolarHBondContact O-N 3.17Å; A381-V385 PolarHBondContact O-N 3.46Å
382A95Very high96.7Very high1 Ų120.6 Ų20.61%0.00812%0.115CC..Hα-helixtrans-57.7-37.1179.600000112.4F295 M328 Y378 I384F295-A382 HydrophobicContact CE2-CB 3.5Å; F295-A382 HydrophobicContact CZ-CB 3.93Å; M328-A382 HydrophobicContact CE-CB 3.81Å; M328-A382 HydrophobicContact SD-CB 4.1Å; Y378-A382 WeakPolarHBondContact O-CB 3.45Å; Y378-A382 PolarHBondContact O-N 3.03Å; A382-I384 PolarHBondContact O-N 3.43Å
383A96.9Very high96.6Very high0 Ų018.2 Ų18.20%010%0.098CC..Hα-helixtrans-59.8-27176.900000113.9M328 I331 Q332 S379 A381 P387M328-A383 HydrophobicContact CB-CB 4.34Å; M328-A383 HydrophobicContact CG-CB 4.32Å; I331-A383 HydrophobicContact CB-CB 3.72Å; I331-A383 HydrophobicContact CG2-CB 3.56Å; Q332-A383 HydrophobicContact CG-CB 3.85Å; Q332-A383 WeakPolarHBondContact CG-O 3.38Å; S379-A383 WeakPolarHBondContact O-CB 3.5Å; S379-A383 PolarHBondContact O-N 3.36Å; S379-A383 VanDerWaalsContact O-N 3.08Å; A381-A383 PolarHBondContact O-N 2.91Å; A383-P387 WeakPolarHBondContact O-CG 3.49Å
384I97.4Very high96.4Very high4 Ų414.9 Ų14.92%0.0218%0.078CC..Hα-helixtrans-96.3-42.1-172.1-64.3165.2000111.8I331 Y335 I339 A347 A351 F380 A381 A382 P387 C388I331-I384 HydrophobicContact CG2-CG1 4.33Å; Y335-I384 HydrophobicContact CD1-CD1 3.8Å; Y335-I384 HydrophobicContact CD1-CG1 4.1Å; Y335-I384 HydrophobicContact CE1-CD1 3.66Å; Y335-I384 HydrophobicContact CE1-CG1 4.27Å; I339-I384 HydrophobicContact CD1-CG2 4.2Å; A347-I384 HydrophobicContact CB-CG2 3.97Å; A351-I384 HydrophobicContact CB-CB 4.03Å; A351-I384 HydrophobicContact CB-CD1 4.39Å; A351-I384 HydrophobicContact CB-CG2 4.14Å; F380-I384 HydrophobicContact CD1-CD1 3.91Å; F380-I384 HydrophobicContact CE1-CD1 3.51Å; F380-I384 HydrophobicContact CZ-CD1 4.12Å; F380-I384 WeakPolarHBondContact O-CD1 3.34Å; A381-I384 PolarHBondContact O-N 3.17Å; A382-I384 PolarHBondContact O-N 3.43Å; I384-P387 WeakPolarHBondContact O-CD 3.4Å; I384-C388 VanDerWaalsContact O-CB 3.28Å; I384-C388 WeakPolarHBondContact O-CB 3.35Å; I384-C388 PolarHBondContact O-N 3.39Å; I384-C388 VanDerWaalsContact O-N 3.15Å; I384-C388 PolarHBondContact O-SG 2.85Å; I384-C388 VanDerWaalsContact O-SG 3.42Å
385V97Very high96Very high0 Ų016.1 Ų16.10%09%0.091CC..Hα-helixtrans-62.7-53.5-164.2176.90000112.9Y291 V348 A351 I352 A381 L389Y291-V385 HydrophobicContact CD1-CG1 3.67Å; Y291-V385 HydrophobicContact CD2-CB 4.28Å; Y291-V385 HydrophobicContact CD2-CG1 3.6Å; Y291-V385 HydrophobicContact CD2-CG2 4.33Å; Y291-V385 HydrophobicContact CE1-CB 4.01Å; Y291-V385 HydrophobicContact CE1-CG1 3.65Å; Y291-V385 HydrophobicContact CE2-CB 3.69Å; Y291-V385 HydrophobicContact CE2-CG1 3.53Å; Y291-V385 HydrophobicContact CE2-CG2 3.7Å; Y291-V385 HydrophobicContact CG-CG1 3.67Å; V348-V385 HydrophobicContact CG1-CG1 4.04Å; V348-V385 HydrophobicContact CG1-CG2 4.4Å; A351-V385 HydrophobicContact CB-CG2 3.72Å; I352-V385 HydrophobicContact CG1-CG2 4.16Å; A381-V385 PolarHBondContact O-N 3.46Å; V385-L389 HydrophobicContact CG1-CD1 3.66Å; V385-L389 HydrophobicContact CG1-CG 4.27Å; V385-L389 WeakPolarHBondContact O-CB 3.47Å; V385-L389 WeakPolarHBondContact O-CG 3.38Å; V385-L389 PolarHBondContact O-N 3.19Å
386I95.1Very high95.7Very high43 Ų4316.6 Ų16.622%0.2219%0.092CC..Hα-helixtrans-64.8-50.1-175-63172.1000111.6Y288 Y291 L292 C388 S390Y288-I386 HydrophobicContact CE2-CG2 4.21Å; Y291-I386 HydrophobicContact CD1-CG1 4.49Å; Y291-I386 HydrophobicContact CE1-CD1 4.23Å; Y291-I386 HydrophobicContact CE1-CG1 3.74Å; L292-I386 HydrophobicContact CD2-CD1 3.75Å; L292-I386 HydrophobicContact CD2-CG1 4.34Å; I386-C388 PolarHBondContact O-N 2.82Å; I386-S390 VanDerWaalsContact O-CB 3.29Å; I386-S390 WeakPolarHBondContact O-CB 3.23Å; I386-S390 PolarHBondContact O-N 3.12Å; I386-S390 PolarHBondContact O-OG 3.34Å
387P95.1Very high95.1Very high6 Ų613.5 Ų13.54%0.0398%0.081CC..Hα-helixtrans-59.3-43.5178.3-28.538000113.6M177 A178 A383 I384 S390 A391M177-P387 HydrophobicContact CB-CB 4.49Å; M177-P387 WeakPolarHBondContact CB-O 3.47Å; A178-P387 HydrophobicContact CB-CB 4.43Å; A383-P387 WeakPolarHBondContact O-CG 3.49Å; I384-P387 WeakPolarHBondContact O-CD 3.4Å; P387-S390 PolarHBondContact O-N 2.95Å; P387-A391 VanDerWaalsContact O-CB 3.29Å; P387-A391 WeakPolarHBondContact O-CB 3.16Å; P387-A391 PolarHBondContact O-N 3.24Å
388C96.4Very high94.5Very high5 Ų512.7 Ų12.73%0.0348%0.081CC..Hα-helixtrans-69.6-43.1-178.3-74.40000112.6I339 E344 V348 I384 I386 S390 A391 V392I339-C388 VanDerWaalsContact CD1-SG 3.53Å; E344-C388 HydrophobicContact CB-CB 3.96Å; E344-C388 HydrophobicContact CG-CB 4.4Å; V348-C388 HydrophobicContact CG2-CB 3.37Å; I384-C388 VanDerWaalsContact O-CB 3.28Å; I384-C388 WeakPolarHBondContact O-CB 3.35Å; I384-C388 PolarHBondContact O-N 3.39Å; I384-C388 VanDerWaalsContact O-N 3.15Å; I384-C388 PolarHBondContact O-SG 2.85Å; I384-C388 VanDerWaalsContact O-SG 3.42Å; I386-C388 PolarHBondContact O-N 2.82Å; C388-S390 VanDerWaalsContact C-N 3.34Å; C388-A391 PolarHBondContact O-N 3.48Å; C388-V392 WeakPolarHBondContact O-CG2 3.46Å; C388-V392 PolarHBondContact O-N 2.99Å
389L96.4Very high93.8Very high1 Ų114.8 Ų14.81%0.00510%0.099CC..Hα-helixtrans-63.2-42.3174.8-73.7178.6000111.4L284 Y288 I345 V348 V385 A391 V392 V393 L451L284-L389 HydrophobicContact CD2-CD2 4.07Å; Y288-L389 HydrophobicContact CD2-CB 3.99Å; Y288-L389 HydrophobicContact CD2-CD1 3.89Å; I345-L389 HydrophobicContact CD1-CD2 4.39Å; V348-L389 HydrophobicContact CG1-CD1 4.39Å; V348-L389 HydrophobicContact CG1-CD2 4.09Å; V348-L389 HydrophobicContact CG1-CG 4.11Å; V348-L389 HydrophobicContact CG2-CD2 4.2Å; V348-L389 HydrophobicContact CG2-CG 4.04Å; V385-L389 HydrophobicContact CG1-CD1 3.66Å; V385-L389 HydrophobicContact CG1-CG 4.27Å; V385-L389 WeakPolarHBondContact O-CB 3.47Å; V385-L389 WeakPolarHBondContact O-CG 3.38Å; V385-L389 PolarHBondContact O-N 3.19Å; L389-A391 VanDerWaalsContact C-N 3.32Å; L389-A391 PolarHBondContact O-N 2.59Å; L389-V392 PolarHBondContact O-N 3.27Å; L389-V393 WeakPolarHBondContact O-CB 3.33Å; L389-V393 VanDerWaalsContact O-CG2 3.32Å; L389-V393 WeakPolarHBondContact O-CG2 3.06Å; L389-V393 PolarHBondContact O-N 3.36Å; L389-L451 HydrophobicContact CD2-CD1 4.41Å; L389-L451 HydrophobicContact CD2-CD2 3.94Å
390S96.1Very high93Very high8 Ų815.6 Ų15.66%0.05610%0.104CC..Hα-helixtrans-64.5-38.1177.9-54.30000111.7I386 P387 C388 S394I386-S390 VanDerWaalsContact O-CB 3.29Å; I386-S390 WeakPolarHBondContact O-CB 3.23Å; I386-S390 PolarHBondContact O-N 3.12Å; I386-S390 PolarHBondContact O-OG 3.34Å; P387-S390 PolarHBondContact O-N 2.95Å; C388-S390 VanDerWaalsContact C-N 3.34Å; S390-S394 VanDerWaalsContact O-CB 3.29Å; S390-S394 WeakPolarHBondContact O-CB 3.37Å; S390-S394 PolarHBondContact O-N 3Å
391A95.1Very high92.6Very high7 Ų712.2 Ų12.26%0.0589%0.09CC..Hα-helixtrans-63.4-45.6175.400000111.8M177 P387 C388 L389 S394 G395M177-A391 HydrophobicContact CB-CB 4.27Å; M177-A391 HydrophobicContact CG-CB 4.13Å; P387-A391 VanDerWaalsContact O-CB 3.29Å; P387-A391 WeakPolarHBondContact O-CB 3.16Å; P387-A391 PolarHBondContact O-N 3.24Å; C388-A391 PolarHBondContact O-N 3.48Å; L389-A391 VanDerWaalsContact C-N 3.32Å; L389-A391 PolarHBondContact O-N 2.59Å; A391-S394 PolarHBondContact O-N 3.24Å; A391-S394 PolarHBondContact O-OG 2.96Å; A391-G395 PolarHBondContact O-N 3.28Å
392V95Very high92.3Very high24 Ų2412.9 Ų12.915%0.1459%0.092CC..Hα-helixtrans-65.3-46177.4177.70000110.9L284 E344 I345 C388 L389 S394 G395 Y396L284-V392 HydrophobicContact CD1-CG1 3.73Å; L284-V392 HydrophobicContact CD2-CG1 4.27Å; E344-V392 HydrophobicContact CB-CG2 3.49Å; E344-V392 VanDerWaalsContact CB-CG2 3.49Å; E344-V392 HydrophobicContact CG-CG2 4.13Å; I345-V392 HydrophobicContact CD1-CB 4.33Å; I345-V392 HydrophobicContact CD1-CG1 4.12Å; I345-V392 HydrophobicContact CD1-CG2 3.93Å; I345-V392 HydrophobicContact CG1-CG1 4.47Å; I345-V392 HydrophobicContact CG1-CG2 4.11Å; C388-V392 WeakPolarHBondContact O-CG2 3.46Å; C388-V392 PolarHBondContact O-N 2.99Å; L389-V392 PolarHBondContact O-N 3.27Å; V392-S394 VanDerWaalsContact C-N 3.3Å; V392-S394 PolarHBondContact O-N 3.35Å; V392-G395 VanDerWaalsContact O-CA 3.31Å; V392-G395 WeakPolarHBondContact O-CA 3.36Å; V392-G395 PolarHBondContact O-N 2.83Å; V392-Y396 HydrophobicContact CG1-CE2 4.01Å; V392-Y396 WeakPolarHBondContact O-CD2 3.49Å; V392-Y396 VanDerWaalsContact O-CE2 3.32Å; V392-Y396 WeakPolarHBondContact O-CE2 3.49Å
393V95.3Very high92.1Very high0 Ų012.8 Ų12.80%09%0.092CC..Hα-helixtrans-62.2-37.1178171.20000111.8L281 L284 L389 G395 Y396 V405 M406 L409L281-V393 HydrophobicContact CD1-CG1 3.79Å; L281-V393 HydrophobicContact CD1-CG2 4.4Å; L284-V393 HydrophobicContact CB-CG2 3.84Å; L284-V393 HydrophobicContact CD1-CG2 4.08Å; L284-V393 HydrophobicContact CG-CG2 4.5Å; L389-V393 WeakPolarHBondContact O-CB 3.33Å; L389-V393 VanDerWaalsContact O-CG2 3.32Å; L389-V393 WeakPolarHBondContact O-CG2 3.06Å; L389-V393 PolarHBondContact O-N 3.36Å; V393-G395 PolarHBondContact O-N 2.92Å; V393-G395 VanDerWaalsContact O-N 3.1Å; V393-Y396 PolarHBondContact O-N 3.07Å; V393-V405 HydrophobicContact CG1-CG1 3.59Å; V393-M406 HydrophobicContact CG1-SD 4.12Å; V393-L409 HydrophobicContact CB-CD2 3.93Å; V393-L409 HydrophobicContact CG1-CB 4.37Å; V393-L409 HydrophobicContact CG1-CD1 4.35Å; V393-L409 HydrophobicContact CG1-CD2 3.87Å; V393-L409 HydrophobicContact CG1-CG 4.42Å; V393-L409 HydrophobicContact CG2-CD1 4.09Å; V393-L409 HydrophobicContact CG2-CD2 4.19Å
394S93.8Very high91.8Very high0 Ų014 Ų140%010%0.097CC..Hα-helixtrans-61.6-18.9173.781.20000113.5R173 S390 A391 V392 Y396 K402R173-S394 PolarHBondContact NH1-O 2.92Å; S390-S394 VanDerWaalsContact O-CB 3.29Å; S390-S394 WeakPolarHBondContact O-CB 3.37Å; S390-S394 PolarHBondContact O-N 3Å; A391-S394 PolarHBondContact O-N 3.24Å; A391-S394 PolarHBondContact O-OG 2.96Å; V392-S394 VanDerWaalsContact C-N 3.3Å; V392-S394 PolarHBondContact O-N 3.35Å; S394-Y396 VanDerWaalsContact C-N 3.26Å; S394-Y396 PolarHBondContact O-N 2.64Å; S394-K402 PolarHBondContact O-NZ 3.38Å
395G90.6Very high91.6Very high26 Ų2613.9 Ų13.927%0.26810%0.096SC..THydrogen-bonded Turntrans-52.9-40.516800000113.6A391 V392 V393 K402A391-G395 PolarHBondContact O-N 3.28Å; V392-G395 VanDerWaalsContact O-CA 3.31Å; V392-G395 WeakPolarHBondContact O-CA 3.36Å; V392-G395 PolarHBondContact O-N 2.83Å; V393-G395 PolarHBondContact O-N 2.92Å; V393-G395 VanDerWaalsContact O-N 3.1Å; G395-K402 PolarHBondContact O-NZ 3.21Å
396Y89.9Confident91.5Very high14 Ų1414 Ų146%0.05510%0.096CC..SBendtrans-91.9161.1-166.5-63-91.1000113.3N277 N280 L281 L284 V392 V393 S394 K402N277-Y396 HydrophobicContact CB-CD1 3.92Å; N277-Y396 HydrophobicContact CB-CE1 3.94Å; N280-Y396 HydrophobicContact CB-CE1 4.07Å; L281-Y396 HydrophobicContact CD1-CD2 4.31Å; L281-Y396 HydrophobicContact CD1-CG 4.26Å; L284-Y396 HydrophobicContact CD1-CD2 4.38Å; L284-Y396 HydrophobicContact CD1-CE2 3.63Å; V392-Y396 HydrophobicContact CG1-CE2 4.01Å; V392-Y396 WeakPolarHBondContact O-CD2 3.49Å; V392-Y396 VanDerWaalsContact O-CE2 3.32Å; V392-Y396 WeakPolarHBondContact O-CE2 3.49Å; V393-Y396 PolarHBondContact O-N 3.07Å; S394-Y396 VanDerWaalsContact C-N 3.26Å; S394-Y396 PolarHBondContact O-N 2.64Å; Y396-K402 PolarHBondContact O-NZ 2.9Å
397G85.3Confident91.4Very high21 Ų2111.9 Ų11.922%0.2169%0.086CC..SBendtrans77152-178.800000113.4K402G397-K402 WeakPolarHBondContact O-CE 3.47Å; G397-K402 PolarHBondContact O-NZ 3.46Å
398A85.4Confident91.4Very high29 Ų2911.7 Ų11.724%0.248%0.084CC..  trans-64.1166.2174.700000111.6D271 S400 Q401 K402D271-A398 HydrophobicContact CB-CB 3.78Å; A398-S400 PolarHBondContact O-N 3.5Å; A398-Q401 HydrophobicContact CB-CG 4.35Å; A398-Q401 VanDerWaalsContact N-OE1 3.1Å; A398-Q401 PolarHBondContact O-N 2.82Å; A398-K402 PolarHBondContact O-N 3.3Å
399A82.4Confident91.3Very high45 Ų4511.5 Ų11.537%0.3728%0.083SC..G310 helixtrans-56.1-34.2176.800000112.4K239 Q401K239-A399 HydrophobicContact CD-CB 4.17Å; A399-Q401 PolarHBondContact O-N 3.33Å
400S82Confident91.3Very high17 Ų1712.6 Ų12.612%0.1199%0.087CC..G310 helixtrans-74.1-5.9177.559.80000114.6D112 K239 A398D112-S400 VanDerWaalsContact CB-O 3.23Å; D112-S400 WeakPolarHBondContact CB-O 3.34Å; K239-S400 WeakPolarHBondContact O-CB 3.18Å; A398-S400 PolarHBondContact O-N 3.5Å
401Q87.6Confident91.2Very high5 Ų512.2 Ų12.22%0.0238%0.084CC..G310 helixtrans-120-1.6-172.5-64.9174.3-2200113.5D271 A398 A399 G403 R404 V405D271-Q401 PolarHBondContact O-NE2 3.08Å; D271-Q401 PolarHBondContact O-OE1 3.1Å; A398-Q401 HydrophobicContact CB-CG 4.35Å; A398-Q401 VanDerWaalsContact N-OE1 3.1Å; A398-Q401 PolarHBondContact O-N 2.82Å; A399-Q401 PolarHBondContact O-N 3.33Å; Q401-G403 PolarHBondContact O-N 3.05Å; Q401-R404 PolarHBondContact O-N 3.42Å; Q401-V405 WeakPolarHBondContact O-CG2 2.99Å; Q401-V405 PolarHBondContact O-N 3.17Å
402K90.8Very high91.3Very high14 Ų1411.9 Ų11.96%0.0618%0.082CC..Hα-helixtrans-59.5-34.1-176-63.3-56.2-172.2-172.80112.3A165 S394 G395 Y396 G397 A398 M406A165-K402 HydrophobicContact CB-CB 4.11Å; A165-K402 HydrophobicContact CB-CD 4.13Å; A165-K402 HydrophobicContact CB-CG 4.26Å; S394-K402 PolarHBondContact O-NZ 3.38Å; G395-K402 PolarHBondContact O-NZ 3.21Å; Y396-K402 PolarHBondContact O-NZ 2.9Å; G397-K402 WeakPolarHBondContact O-CE 3.47Å; G397-K402 PolarHBondContact O-NZ 3.46Å; A398-K402 PolarHBondContact O-N 3.3Å; K402-M406 WeakPolarHBondContact O-CB 3.36Å; K402-M406 WeakPolarHBondContact O-CG 3.38Å; K402-M406 PolarHBondContact O-N 3.49Å
403G90.4Very high91.4Very high0 Ų010.8 Ų10.80%08%0.075CC..Hα-helixtrans-63.2-49.8175.700000112G108 D112 Q401 G407G108-G403 WeakPolarHBondContact CA-O 3.45Å; D112-G403 WeakPolarHBondContact OD1-CA 3.48Å; D112-G403 PolarHBondContact OD1-N 3.31Å; D112-G403 WeakPolarHBondContact OD2-CA 3.44Å; D112-G403 PolarHBondContact OD2-N 3.07Å; Q401-G403 PolarHBondContact O-N 3.05Å; G403-G407 WeakPolarHBondContact O-CA 3.37Å; G403-G407 PolarHBondContact O-N 3.04Å
404R90.7Very high91.4Very high26 Ų2610.8 Ų10.810%0.0988%0.075CC..Hα-helixtrans-60.2-49.2174.5-73174.5-156.4-172.43.7112.2A109 D112 A265 V266 Q401 M406 G407 I408A109-R404 HydrophobicContact CB-CG 3.87Å; D112-R404 WeakPolarHBondContact OD2-CG 3.32Å; D112-R404 PolarHBondContact OD2-N 2.99Å; A265-R404 PolarHBondContact O-NH1 2.95Å; V266-R404 HydrophobicContact CG2-CB 4.26Å; Q401-R404 PolarHBondContact O-N 3.42Å; R404-M406 PolarHBondContact O-N 3.13Å; R404-G407 PolarHBondContact O-N 3.22Å; R404-I408 WeakPolarHBondContact O-CB 3.49Å; R404-I408 WeakPolarHBondContact O-CG1 3.18Å; R404-I408 PolarHBondContact O-N 3.32Å
405V92.9Very high91.5Very high0 Ų012.1 Ų12.10%08%0.082CC..Hα-helixtrans-58.5-50.9-177.6171.20000110.8V266 L281 V393 Q401 L409V266-V405 HydrophobicContact CG1-CG2 4.07Å; V266-V405 HydrophobicContact CG2-CG2 3.82Å; L281-V405 HydrophobicContact CD1-CG1 4.28Å; V393-V405 HydrophobicContact CG1-CG1 3.59Å; Q401-V405 WeakPolarHBondContact O-CG2 2.99Å; Q401-V405 PolarHBondContact O-N 3.17Å; V405-L409 PolarHBondContact O-N 3.06Å; V405-L409 VanDerWaalsContact O-N 3.1Å
406M94.8Very high91.8Very high2 Ų210.9 Ų10.91%0.017%0.069CC..Hα-helixtrans-72.4-32-179.9-63-48.4-63.900112.4T161 A162 A165 M177 V393 K402 R404 L409 R410T161-M406 HydrophobicContact CG2-CE 4.44Å; A162-M406 HydrophobicContact CB-CB 4.41Å; A165-M406 HydrophobicContact CB-CG 4.07Å; M177-M406 HydrophobicContact CE-CE 3.71Å; M177-M406 HydrophobicContact CE-SD 4.42Å; M177-M406 HydrophobicContact SD-CE 4.5Å; V393-M406 HydrophobicContact CG1-SD 4.12Å; K402-M406 WeakPolarHBondContact O-CB 3.36Å; K402-M406 WeakPolarHBondContact O-CG 3.38Å; K402-M406 PolarHBondContact O-N 3.49Å; R404-M406 PolarHBondContact O-N 3.13Å; M406-L409 HydrophobicContact CE-CD2 3.85Å; M406-L409 PolarHBondContact O-N 2.95Å; M406-R410 WeakPolarHBondContact O-CB 3.26Å; M406-R410 PolarHBondContact O-N 3.22Å
407G93.9Very high92Very high0 Ų013.1 Ų13.10%08%0.078CC..Hα-helixtrans-63.4-43.8173.600000113.3S158 G403 R404 R410 S411S158-G407 VanDerWaalsContact OG-CA 3.24Å; S158-G407 WeakPolarHBondContact OG-CA 3.44Å; S158-G407 PolarHBondContact OG-N 3.46Å; G403-G407 WeakPolarHBondContact O-CA 3.37Å; G403-G407 PolarHBondContact O-N 3.04Å; R404-G407 PolarHBondContact O-N 3.22Å; G407-R410 PolarHBondContact O-N 3.27Å; G407-S411 VanDerWaalsContact O-CB 3.28Å; G407-S411 WeakPolarHBondContact O-CB 3.27Å; G407-S411 PolarHBondContact O-N 2.96Å
408I94.3Very high92.5Very high1 Ų112.4 Ų12.41%0.0057%0.069CC..Hα-helixtrans-62.8-48.3173.6-66.5166.1000109.9L254 L260 F263 A265 V266 R404 R410 S411 L412L254-I408 HydrophobicContact CD2-CG1 4.44Å; L260-I408 HydrophobicContact CB-CG2 4.17Å; L260-I408 HydrophobicContact CD2-CB 4.24Å; L260-I408 HydrophobicContact CD2-CG1 3.73Å; L260-I408 HydrophobicContact CD2-CG2 3.99Å; L260-I408 WeakPolarHBondContact O-CG2 3.35Å; F263-I408 HydrophobicContact CD1-CB 4.09Å; F263-I408 HydrophobicContact CD1-CD1 3.86Å; F263-I408 HydrophobicContact CD1-CG2 3.66Å; F263-I408 HydrophobicContact CE1-CB 3.89Å; F263-I408 HydrophobicContact CE1-CG2 3.43Å; F263-I408 VanDerWaalsContact CE1-CG2 3.43Å; F263-I408 HydrophobicContact CE2-CG2 4.4Å; F263-I408 HydrophobicContact CG-CG2 4.25Å; F263-I408 HydrophobicContact CZ-CG2 3.84Å; A265-I408 HydrophobicContact CB-CD1 4.41Å; V266-I408 HydrophobicContact CG2-CD1 3.8Å; R404-I408 WeakPolarHBondContact O-CB 3.49Å; R404-I408 WeakPolarHBondContact O-CG1 3.18Å; R404-I408 PolarHBondContact O-N 3.32Å; I408-R410 VanDerWaalsContact C-N 3.28Å; I408-R410 PolarHBondContact O-N 2.86Å; I408-S411 WeakPolarHBondContact O-CB 3.41Å; I408-S411 PolarHBondContact O-N 3.38Å; I408-S411 VanDerWaalsContact O-N 3.16Å; I408-L412 HydrophobicContact CG2-CD1 4.29Å; I408-L412 HydrophobicContact CG2-CG 4.41Å; I408-L412 WeakPolarHBondContact O-CG 3.4Å; I408-L412 PolarHBondContact O-N 2.99Å
409L95.4Very high92.9Very high2 Ų215.4 Ų15.41%0.018%0.079CC..Hα-helixtrans-57.2-44177.8-170.770.8000111.3Y288 V393 V405 M406 S411 L412 G413Y288-L409 HydrophobicContact CD1-CD1 3.59Å; Y288-L409 HydrophobicContact CD1-CG 3.95Å; Y288-L409 HydrophobicContact CD2-CD1 4.05Å; Y288-L409 HydrophobicContact CD2-CG 4.4Å; Y288-L409 HydrophobicContact CE1-CD1 4.09Å; Y288-L409 HydrophobicContact CE1-CG 3.91Å; Y288-L409 WeakPolarHBondContact CE1-O 3.48Å; Y288-L409 HydrophobicContact CE2-CD2 4.41Å; Y288-L409 HydrophobicContact CE2-CG 4.39Å; Y288-L409 HydrophobicContact CG-CD1 3.57Å; Y288-L409 HydrophobicContact CG-CG 4.2Å; V393-L409 HydrophobicContact CB-CD2 3.93Å; V393-L409 HydrophobicContact CG1-CB 4.37Å; V393-L409 HydrophobicContact CG1-CD1 4.35Å; V393-L409 HydrophobicContact CG1-CD2 3.87Å; V393-L409 HydrophobicContact CG1-CG 4.42Å; V393-L409 HydrophobicContact CG2-CD1 4.09Å; V393-L409 HydrophobicContact CG2-CD2 4.19Å; V405-L409 PolarHBondContact O-N 3.06Å; V405-L409 VanDerWaalsContact O-N 3.1Å; M406-L409 HydrophobicContact CE-CD2 3.85Å; M406-L409 PolarHBondContact O-N 2.95Å; L409-S411 VanDerWaalsContact C-N 3.34Å; L409-S411 PolarHBondContact O-N 3.41Å; L409-L412 PolarHBondContact O-N 2.88Å; L409-G413 PolarHBondContact O-N 3.11Å
410R94.8Very high93.5Very high24 Ų2413.2 Ų13.29%0.0916%0.062CC..Hα-helixtrans-67-36.9179.3-17362.4-173.982.5-1.5112.6Q100 M406 G407 I408 G413 A414Q100-R410 VanDerWaalsContact OE1-CZ 3.25Å; M406-R410 WeakPolarHBondContact O-CB 3.26Å; M406-R410 PolarHBondContact O-N 3.22Å; G407-R410 PolarHBondContact O-N 3.27Å; I408-R410 VanDerWaalsContact C-N 3.28Å; I408-R410 PolarHBondContact O-N 2.86Å; R410-G413 PolarHBondContact O-N 2.99Å; R410-A414 WeakPolarHBondContact O-CB 3.44Å; R410-A414 PolarHBondContact O-N 3.34Å
411S95.3Very high94.1Very high0 Ų013.1 Ų13.10%06%0.061CC..Hα-helixtrans-65.9-47.7175.5177.10000112F101 P105 L260 G407 I408 L409 G413 A414 L415F101-S411 WeakPolarHBondContact CD2-O 3.32Å; F101-S411 WeakPolarHBondContact CD2-OG 3.32Å; F101-S411 WeakPolarHBondContact CE2-OG 3.2Å; F101-S411 WeakPolarHBondContact O-CB 3.48Å; F101-S411 PolarHBondContact O-OG 2.84Å; P105-S411 WeakPolarHBondContact CG-OG 3.33Å; L260-S411 WeakPolarHBondContact CD1-OG 3.49Å; G407-S411 VanDerWaalsContact O-CB 3.28Å; G407-S411 WeakPolarHBondContact O-CB 3.27Å; G407-S411 PolarHBondContact O-N 2.96Å; I408-S411 WeakPolarHBondContact O-CB 3.41Å; I408-S411 PolarHBondContact O-N 3.38Å; I408-S411 VanDerWaalsContact O-N 3.16Å; L409-S411 VanDerWaalsContact C-N 3.34Å; L409-S411 PolarHBondContact O-N 3.41Å; S411-G413 PolarHBondContact O-N 3.33Å; S411-A414 CarbonylContact O-C 3.52Å; S411-A414 WeakPolarHBondContact O-CA 3.16Å; S411-A414 WeakPolarHBondContact O-CB 3.25Å; S411-A414 PolarHBondContact O-N 2.93Å; S411-L415 PolarHBondContact O-N 3.25Å
412L96.4Very high94.3Very high0 Ų016.5 Ų16.50%08%0.078CC..Hα-helixtrans-54.6-44.2172.1-69.3177.4000111L260 F261 F263 F289 I408 L409 A414 L415 A416L260-L412 HydrophobicContact CB-CD2 4.02Å; F261-L412 HydrophobicContact CD1-CD1 4.49Å; F261-L412 HydrophobicContact CD1-CD2 3.91Å; F261-L412 HydrophobicContact CD2-CD2 4.07Å; F261-L412 HydrophobicContact CE1-CD2 3.81Å; F261-L412 HydrophobicContact CE2-CD2 3.94Å; F261-L412 HydrophobicContact CG-CD2 4.04Å; F261-L412 HydrophobicContact CZ-CD2 3.82Å; F263-L412 HydrophobicContact CE2-CD1 4.31Å; F263-L412 HydrophobicContact CZ-CD1 4.21Å; F289-L412 HydrophobicContact CB-CB 4.47Å; F289-L412 WeakPolarHBondContact CD2-O 3.38Å; I408-L412 HydrophobicContact CG2-CD1 4.29Å; I408-L412 HydrophobicContact CG2-CG 4.41Å; I408-L412 WeakPolarHBondContact O-CG 3.4Å; I408-L412 PolarHBondContact O-N 2.99Å; L409-L412 PolarHBondContact O-N 2.88Å; L412-A414 VanDerWaalsContact C-N 3.32Å; L412-A414 PolarHBondContact O-N 2.85Å; L412-L415 PolarHBondContact O-N 2.99Å; L412-A416 WeakPolarHBondContact O-CB 3.43Å; L412-A416 PolarHBondContact O-N 3.46Å
413G96.4Very high94.4Very high0 Ų019.7 Ų19.70%010%0.095CC..Hα-helixtrans-64.6-32.5174.500000114.4L409 R410 S411 R417L409-G413 PolarHBondContact O-N 3.11Å; R410-G413 PolarHBondContact O-N 2.99Å; S411-G413 PolarHBondContact O-N 3.33Å; G413-R417 WeakPolarHBondContact O-CG 3.3Å; G413-R417 PolarHBondContact O-N 3.24Å; G413-R417 VanDerWaalsContact O-N 3.1Å
414A95.7Very high94.6Very high1 Ų119.7 Ų19.71%0.00810%0.095CC..Hα-helixtrans-72-42.1176.100000111.6S97 Q100 F101 R410 S411 L412 A416 R417 A418S97-A414 WeakPolarHBondContact CB-O 3.47Å; S97-A414 WeakPolarHBondContact O-CB 3.47Å; Q100-A414 HydrophobicContact CB-CB 3.82Å; F101-A414 HydrophobicContact CB-CB 4.09Å; R410-A414 WeakPolarHBondContact O-CB 3.44Å; R410-A414 PolarHBondContact O-N 3.34Å; S411-A414 CarbonylContact O-C 3.52Å; S411-A414 WeakPolarHBondContact O-CA 3.16Å; S411-A414 WeakPolarHBondContact O-CB 3.25Å; S411-A414 PolarHBondContact O-N 2.93Å; L412-A414 VanDerWaalsContact C-N 3.32Å; L412-A414 PolarHBondContact O-N 2.85Å; A414-A416 VanDerWaalsContact C-N 3.31Å; A414-A416 PolarHBondContact O-N 2.87Å; A414-R417 PolarHBondContact O-N 3.38Å; A414-A418 PolarHBondContact O-N 2.91Å
415L95.9Very high94.8Very high27 Ų2718.5 Ų18.514%0.1419%0.091CC..Hα-helixtrans-59-44.7172.2-174.262.4000111.2F101 P257 F261 F289 S411 L412 R417 A418 M419F101-L415 HydrophobicContact CD2-CB 3.62Å; F101-L415 HydrophobicContact CD2-CD1 4.33Å; F101-L415 HydrophobicContact CD2-CD2 4.43Å; F101-L415 HydrophobicContact CD2-CG 4.34Å; F101-L415 HydrophobicContact CE2-CB 3.98Å; F101-L415 HydrophobicContact CE2-CD1 4.36Å; F101-L415 HydrophobicContact CE2-CD2 3.95Å; F101-L415 HydrophobicContact CE2-CG 4.33Å; F101-L415 HydrophobicContact CG-CB 4.31Å; F101-L415 HydrophobicContact CG-CD1 4.5Å; F101-L415 HydrophobicContact CZ-CD2 4.46Å; P257-L415 HydrophobicContact CB-CD2 4.26Å; F261-L415 HydrophobicContact CE2-CD2 4.48Å; F289-L415 HydrophobicContact CE2-CB 4.18Å; F289-L415 HydrophobicContact CE2-CD2 3.98Å; F289-L415 HydrophobicContact CE2-CG 3.94Å; S411-L415 PolarHBondContact O-N 3.25Å; L412-L415 PolarHBondContact O-N 2.99Å; L415-R417 VanDerWaalsContact C-N 3.34Å; L415-R417 PolarHBondContact O-N 3.37Å; L415-A418 WeakPolarHBondContact O-CB 3.3Å; L415-A418 PolarHBondContact O-N 2.71Å; L415-A418 VanDerWaalsContact O-N 3.16Å; L415-M419 HydrophobicContact CD1-CG 4.41Å; L415-M419 HydrophobicContact CD1-SD 3.96Å; L415-M419 HydrophobicContact CG-SD 4.06Å; L415-M419 WeakPolarHBondContact O-CG 3.46Å; L415-M419 PolarHBondContact O-N 2.98Å; L415-M419 VanDerWaalsContact O-N 3.09Å
416A96.8Very high94.8Very high0 Ų020.2 Ų20.20%010%0.102CC..Hα-helixtrans-57.7-44.4176.300000112.1F289 L292 F293 L412 A414 M419 G420F289-A416 HydrophobicContact CD2-CB 3.73Å; F289-A416 HydrophobicContact CE2-CB 3.91Å; F289-A416 HydrophobicContact CG-CB 4.42Å; F289-A416 WeakPolarHBondContact O-CB 3.34Å; L292-A416 HydrophobicContact CB-CB 3.69Å; F293-A416 HydrophobicContact CB-CB 4.02Å; L412-A416 WeakPolarHBondContact O-CB 3.43Å; L412-A416 PolarHBondContact O-N 3.46Å; A414-A416 VanDerWaalsContact C-N 3.31Å; A414-A416 PolarHBondContact O-N 2.87Å; A416-M419 PolarHBondContact O-N 3.29Å; A416-G420 WeakPolarHBondContact O-CA 3.31Å; A416-G420 PolarHBondContact O-N 3.48Å
417R95.6Very high94.8Very high62 Ų6222 Ų2223%0.23411%0.112CC..Hα-helixtrans-72.9-23.5176.4-70.2-166.1-168.2113-0.4114.4G413 A414 L415 P421G413-R417 WeakPolarHBondContact O-CG 3.3Å; G413-R417 PolarHBondContact O-N 3.24Å; G413-R417 VanDerWaalsContact O-N 3.1Å; A414-R417 PolarHBondContact O-N 3.38Å; L415-R417 VanDerWaalsContact C-N 3.34Å; L415-R417 PolarHBondContact O-N 3.37Å; R417-P421 WeakPolarHBondContact O-CD 3.41Å; R417-P421 WeakPolarHBondContact O-CG 3.34Å
418A94.2Very high94.9Very high5 Ų522.2 Ų22.24%0.04111%0.113CC..Hα-helixtrans-71.4-41.2173.200000111.3S94 I98 A414 L415 I422S94-A418 PolarHBondContact OG-O 3.04Å; I98-A418 HydrophobicContact CD1-CB 4.5Å; I98-A418 HydrophobicContact CG1-CB 3.74Å; A414-A418 PolarHBondContact O-N 2.91Å; L415-A418 WeakPolarHBondContact O-CB 3.3Å; L415-A418 PolarHBondContact O-N 2.71Å; L415-A418 VanDerWaalsContact O-N 3.16Å; A418-I422 WeakPolarHBondContact O-CD1 3.15Å
419M94.6Very high95Very high92 Ų9223.6 Ų23.645%0.45312%0.118SC..Hα-helixtrans-92.5-34.2-173.3-60.9178.565.700114F293 L415 A416 I422 L423F293-M419 HydrophobicContact CD2-CB 4.05Å; F293-M419 HydrophobicContact CE2-CB 3.71Å; L415-M419 HydrophobicContact CD1-CG 4.41Å; L415-M419 HydrophobicContact CD1-SD 3.96Å; L415-M419 HydrophobicContact CG-SD 4.06Å; L415-M419 WeakPolarHBondContact O-CG 3.46Å; L415-M419 PolarHBondContact O-N 2.98Å; L415-M419 VanDerWaalsContact O-N 3.09Å; A416-M419 PolarHBondContact O-N 3.29Å; M419-I422 PolarHBondContact O-N 3.4Å; M419-L423 PolarHBondContact O-N 2.91Å; M419-L423 VanDerWaalsContact O-N 3.07Å
420G95.3Very high95Very high0 Ų029 Ų290%015%0.147CC..Hα-helixtrans-56.3-51.7-175.100000114F293 G297 A416 I422 L423 S424F293-G420 WeakPolarHBondContact O-CA 3.46Å; G297-G420 VanDerWaalsContact CA-C 3.49Å; G297-G420 WeakPolarHBondContact CA-O 3.13Å; A416-G420 WeakPolarHBondContact O-CA 3.31Å; A416-G420 PolarHBondContact O-N 3.48Å; G420-I422 VanDerWaalsContact C-N 3.33Å; G420-I422 PolarHBondContact O-N 3.23Å; G420-L423 PolarHBondContact O-N 2.83Å; G420-S424 WeakPolarHBondContact O-CB 2.92Å; G420-S424 PolarHBondContact O-N 3.21Å; G420-S424 PolarHBondContact O-OG 3.26Å
421P94.1Very high95Very high15 Ų1529.9 Ų29.910%0.09716%0.159CC..Hα-helixtrans-57.2-41.4176-3038.7000113.6Y300 R417 A425Y300-P421 HydrophobicContact CD1-CB 3.61Å; Y300-P421 HydrophobicContact CD2-CB 4.48Å; Y300-P421 HydrophobicContact CE1-CB 4.11Å; Y300-P421 HydrophobicContact CG-CB 3.8Å; Y300-P421 HydrophobicContact CG-CG 4.39Å; R417-P421 WeakPolarHBondContact O-CD 3.41Å; R417-P421 WeakPolarHBondContact O-CG 3.34Å; P421-A425 WeakPolarHBondContact O-CB 3.27Å; P421-A425 PolarHBondContact O-N 2.96Å
422I92.3Very high95Very high75 Ų7531 Ų3139%0.38517%0.171SC..Hα-helixtrans-64-53.7-179.4-59.3174.2000109.6F71 A418 M419 G420 S424 A425 T426F71-I422 HydrophobicContact CE2-CG2 4.04Å; F71-I422 HydrophobicContact CZ-CG2 4.05Å; A418-I422 WeakPolarHBondContact O-CD1 3.15Å; M419-I422 PolarHBondContact O-N 3.4Å; G420-I422 VanDerWaalsContact C-N 3.33Å; G420-I422 PolarHBondContact O-N 3.23Å; I422-S424 PolarHBondContact O-N 2.84Å; I422-A425 PolarHBondContact O-N 2.89Å; I422-T426 PolarHBondContact O-N 3.21Å; I422-T426 PolarHBondContact O-OG1 3.38Å; I422-T426 VanDerWaalsContact O-OG1 3.05Å
423L93.3Very high94.9Very high82 Ų8231.3 Ų31.343%0.42917%0.174SC..Hα-helixtrans-64.2-42.9-178.3-175.5132.5000111.8F293 M419 G420 T426 V427F293-L423 HydrophobicContact CE1-CD2 4.04Å; F293-L423 HydrophobicContact CE2-CB 4.42Å; F293-L423 HydrophobicContact CZ-CB 3.84Å; F293-L423 HydrophobicContact CZ-CD1 3.97Å; F293-L423 HydrophobicContact CZ-CD2 3.86Å; F293-L423 HydrophobicContact CZ-CG 4.07Å; M419-L423 PolarHBondContact O-N 2.91Å; M419-L423 VanDerWaalsContact O-N 3.07Å; G420-L423 PolarHBondContact O-N 2.83Å; L423-T426 PolarHBondContact O-N 3.33Å; L423-V427 HydrophobicContact CD2-CG2 4.34Å; L423-V427 WeakPolarHBondContact O-CG2 3.42Å; L423-V427 PolarHBondContact O-N 3.01Å
424S94.6Very high94.9Very high0 Ų034.6 Ų34.60%019%0.189CC..Hα-helixtrans-69.2-36.5-179.3-59.10000111.9G297 G420 I422 V427 Y428G297-S424 VanDerWaalsContact C-CB 3.5Å; G297-S424 WeakPolarHBondContact CA-OG 3.13Å; G297-S424 WeakPolarHBondContact O-CB 3.38Å; G420-S424 WeakPolarHBondContact O-CB 2.92Å; G420-S424 PolarHBondContact O-N 3.21Å; G420-S424 PolarHBondContact O-OG 3.26Å; I422-S424 PolarHBondContact O-N 2.84Å; S424-V427 PolarHBondContact O-N 3.49Å; S424-Y428 WeakPolarHBondContact O-CB 3.45Å; S424-Y428 PolarHBondContact O-N 3.49Å
425A93.3Very high95Very high1 Ų138.6 Ų38.61%0.00821%0.209CC..Hα-helixtrans-63.7-42.3172.500000111.8Y300 F304 P421 I422 Y428 W429Y300-A425 HydrophobicContact CE1-CB 4.09Å; F304-A425 HydrophobicContact CE2-CB 4.33Å; P421-A425 WeakPolarHBondContact O-CB 3.27Å; P421-A425 PolarHBondContact O-N 2.96Å; I422-A425 PolarHBondContact O-N 2.89Å; A425-Y428 PolarHBondContact O-N 2.97Å; A425-W429 PolarHBondContact O-N 3.08Å
426T93.6Very high95Very high36 Ų3637.3 Ų37.322%0.22120%0.203CC..Hα-helixtrans-58.3-49.3174.4-59.40000111.3F71 V75 I422 L423 Y428 L430F71-T426 WeakPolarHBondContact CZ-OG1 3.42Å; V75-T426 HydrophobicContact CG1-CG2 4.19Å; I422-T426 PolarHBondContact O-N 3.21Å; I422-T426 PolarHBondContact O-OG1 3.38Å; I422-T426 VanDerWaalsContact O-OG1 3.05Å; L423-T426 PolarHBondContact O-N 3.33Å; T426-Y428 PolarHBondContact O-N 3Å; T426-L430 HydrophobicContact CG2-CD1 3.62Å; T426-L430 HydrophobicContact CG2-CG 4.36Å; T426-L430 VanDerWaalsContact O-CB 3.3Å; T426-L430 WeakPolarHBondContact O-CB 3.45Å; T426-L430 VanDerWaalsContact O-CG 3.28Å; T426-L430 WeakPolarHBondContact O-CG 3.2Å; T426-L430 PolarHBondContact O-N 3.28Å
427V95.4Very high95Very high39 Ų3937.3 Ų37.324%0.23620%0.203CC..Hα-helixtrans-65.4-40.7178.6179.50000111.2L423 S424 W429 A431 C436L423-V427 HydrophobicContact CD2-CG2 4.34Å; L423-V427 WeakPolarHBondContact O-CG2 3.42Å; L423-V427 PolarHBondContact O-N 3.01Å; S424-V427 PolarHBondContact O-N 3.49Å; V427-W429 PolarHBondContact O-N 2.92Å; V427-A431 HydrophobicContact CG1-CB 4.4Å; V427-A431 WeakPolarHBondContact O-CA 3.47Å; V427-A431 WeakPolarHBondContact O-CB 3.37Å; V427-A431 PolarHBondContact O-N 2.91Å; V427-C436 HydrophobicContact CB-CB 4.49Å; V427-C436 HydrophobicContact CG1-CB 3.92Å
428Y96.6Very high95.1Very high4 Ų436.4 Ų36.42%0.01620%0.204CC..Hα-helixtrans-59.2-47.4179-175.4-80.7000112T301 F304 L305 Q308 S424 A425 T426 G432 A433 C436 F437T301-Y428 HydrophobicContact CG2-CD2 4.38Å; T301-Y428 HydrophobicContact CG2-CG 4.37Å; F304-Y428 HydrophobicContact CB-CD1 4.25Å; F304-Y428 HydrophobicContact CB-CE1 3.66Å; F304-Y428 HydrophobicContact CB-CE2 4.29Å; F304-Y428 HydrophobicContact CD2-CD1 4.39Å; F304-Y428 HydrophobicContact CG-CE1 4.46Å; L305-Y428 WeakPolarHBondContact CA-OH 2.98Å; L305-Y428 HydrophobicContact CB-CE2 4.11Å; L305-Y428 PolarHBondContact N-OH 3.24Å; Q308-Y428 PolarHBondContact OE1-OH 2.77Å; S424-Y428 WeakPolarHBondContact O-CB 3.45Å; S424-Y428 PolarHBondContact O-N 3.49Å; A425-Y428 PolarHBondContact O-N 2.97Å; T426-Y428 PolarHBondContact O-N 3Å; Y428-G432 CarbonylContact O-C 3.4Å; Y428-G432 WeakPolarHBondContact O-CA 3.46Å; Y428-G432 PolarHBondContact O-N 2.82Å; Y428-A433 HydrophobicContact CD2-CB 4.16Å; Y428-A433 HydrophobicContact CE2-CB 3.43Å; Y428-A433 VanDerWaalsContact CE2-CB 3.43Å; Y428-C436 HydrophobicContact CD2-CB 4.4Å; Y428-F437 HydrophobicContact CD2-CE2 4.25Å; Y428-F437 HydrophobicContact CE2-CE2 4.22Å
429W95.2Very high95.1Very high30 Ų3039.6 Ų39.611%0.11422%0.219CC..Hα-helixtrans-80-31.6-176.6-69.4116.6000113.4V75 M77 P78 Y83 F304 A425 V427V75-W429 HydrophobicContact CB-CB 4.02Å; V75-W429 HydrophobicContact CG2-CB 3.82Å; V75-W429 HydrophobicContact CG2-CG 4.07Å; V75-W429 CarbonylContact O-C 3.55Å; V75-W429 VanDerWaalsContact O-CB 3.28Å; V75-W429 WeakPolarHBondContact O-CB 3.49Å; M77-W429 HydrophobicContact CB-CD2 4.06Å; M77-W429 HydrophobicContact CB-CE3 4.43Å; M77-W429 HydrophobicContact CB-CG 4.23Å; M77-W429 HydrophobicContact CG-CD2 3.88Å; M77-W429 HydrophobicContact CG-CE3 4.22Å; M77-W429 HydrophobicContact CG-CG 4.44Å; M77-W429 HydrophobicContact CG-CH2 4.07Å; M77-W429 HydrophobicContact CG-CZ2 3.69Å; M77-W429 HydrophobicContact CG-CZ3 4.33Å; M77-W429 HydrophobicContact SD-CZ2 4.11Å; P78-W429 HydrophobicContact CG-CZ3 4.07Å; Y83-W429 AromaticContact CD1-CH2 3.89Å; Y83-W429 HydrophobicContact CD1-CH2 3.89Å; Y83-W429 AromaticContact CD1-CZ2 3.96Å; Y83-W429 HydrophobicContact CD1-CZ2 3.96Å; Y83-W429 AromaticContact CD2-CH2 3.63Å; Y83-W429 HydrophobicContact CD2-CH2 3.63Å; Y83-W429 HydrophobicContact CD2-CZ2 4.18Å; Y83-W429 HydrophobicContact CD2-CZ3 4.5Å; Y83-W429 AromaticContact CE1-CH2 3.92Å; Y83-W429 HydrophobicContact CE1-CH2 3.92Å; Y83-W429 HydrophobicContact CE1-CZ2 4.36Å; Y83-W429 AromaticContact CE2-CH2 3.72Å; Y83-W429 HydrophobicContact CE2-CH2 3.72Å; Y83-W429 HydrophobicContact CE2-CZ3 4.44Å; Y83-W429 AromaticContact CG-CH2 3.77Å; Y83-W429 HydrophobicContact CG-CH2 3.77Å; Y83-W429 AromaticContact CG-CZ2 3.89Å; Y83-W429 HydrophobicContact CG-CZ2 3.89Å; Y83-W429 AromaticContact CZ-CH2 3.9Å; F304-W429 HydrophobicContact CB-CZ2 4.27Å; F304-W429 AromaticContact CD1-CZ2 3.77Å; F304-W429 HydrophobicContact CD1-CZ2 3.77Å; F304-W429 HydrophobicContact CD2-CZ2 4.32Å; F304-W429 AromaticContact CD2-NE1 3.95Å; F304-W429 HydrophobicContact CE1-CZ2 4.1Å; F304-W429 AromaticContact CE2-NE1 3.76Å; F304-W429 AromaticContact CG-CZ2 3.89Å; F304-W429 HydrophobicContact CG-CZ2 3.89Å; F304-W429 AromaticContact CZ-NE1 3.99Å; A425-W429 PolarHBondContact O-N 3.08Å; V427-W429 PolarHBondContact O-N 2.92Å
430L95.1Very high95Very high115 Ų11535.4 Ų35.460%0.60220%0.199SC*.Hα-helixtrans-80.9-37.8177.8-67.7178.6000113.7T426T426-L430 HydrophobicContact CG2-CD1 3.62Å; T426-L430 HydrophobicContact CG2-CG 4.36Å; T426-L430 VanDerWaalsContact O-CB 3.3Å; T426-L430 WeakPolarHBondContact O-CB 3.45Å; T426-L430 VanDerWaalsContact O-CG 3.28Å; T426-L430 WeakPolarHBondContact O-CG 3.2Å; T426-L430 PolarHBondContact O-N 3.28Å
431A95.3Very high95Very high43 Ų4335.4 Ų35.436%0.35520%0.199SC..Hα-helixtrans-114.8-7.7-171.400000113.9V427 I435V427-A431 HydrophobicContact CG1-CB 4.4Å; V427-A431 WeakPolarHBondContact O-CA 3.47Å; V427-A431 WeakPolarHBondContact O-CB 3.37Å; V427-A431 PolarHBondContact O-N 2.91Å; A431-I435 HydrophobicContact CB-CB 4.05Å; A431-I435 HydrophobicContact CB-CD1 4.34Å; A431-I435 HydrophobicContact CB-CG2 3.85Å; A431-I435 VanDerWaalsContact O-CD1 3.3Å; A431-I435 WeakPolarHBondContact O-CD1 3.28Å; A431-I435 WeakPolarHBondContact O-CG1 3.48Å
432G95.3Very high95Very high25 Ų2537.4 Ų37.426%0.25821%0.211SC..  trans89.2165.8-177.800000114.1Y428 C436Y428-G432 CarbonylContact O-C 3.4Å; Y428-G432 WeakPolarHBondContact O-CA 3.46Å; Y428-G432 PolarHBondContact O-N 2.82Å; G432-C436 VanDerWaalsContact O-CB 3.31Å; G432-C436 WeakPolarHBondContact O-CB 3.44Å; G432-C436 PolarHBondContact O-N 3.22Å; G432-C436 VanDerWaalsContact O-N 3.07Å
433A95.4Very high95.2Very high6 Ų638.8 Ų38.85%0.0522%0.215CC..Hα-helixtrans-64.5-45.9-173.700000112.4L305 Y428 I435 C436 F437L305-A433 HydrophobicContact CD1-CB 4.26Å; Y428-A433 HydrophobicContact CD2-CB 4.16Å; Y428-A433 HydrophobicContact CE2-CB 3.43Å; Y428-A433 VanDerWaalsContact CE2-CB 3.43Å; A433-I435 PolarHBondContact O-N 3.02Å; A433-C436 PolarHBondContact O-N 3Å; A433-F437 WeakPolarHBondContact O-CB 3.45Å; A433-F437 VanDerWaalsContact O-CD2 3.29Å; A433-F437 WeakPolarHBondContact O-CD2 3.17Å; A433-F437 PolarHBondContact O-N 3.03Å
434E96.3Very high95.3Very high69 Ų6934.9 Ų34.932%0.32219%0.194SC..Hα-helixtrans-60.7-46.5-176.7-63.877.9-172.900110.7R309 W364 T438R309-E434 IonicContact CZ-OE1 3.17Å; R309-E434 VanDerWaalsContact NH2-CD 3.27Å; R309-E434 IonicContact NH2-OE1 3.55Å; R309-E434 PolarHBondContact NH2-OE1 3.12Å; R309-E434 IonicContact NH2-OE2 2.8Å; W364-E434 HydrophobicContact CD2-CB 4.37Å; W364-E434 HydrophobicContact CD2-CG 4.15Å; W364-E434 HydrophobicContact CE3-CG 4.15Å; W364-E434 HydrophobicContact CH2-CB 4.28Å; W364-E434 HydrophobicContact CH2-CG 4.37Å; W364-E434 HydrophobicContact CZ2-CB 3.91Å; W364-E434 HydrophobicContact CZ2-CG 4.36Å; W364-E434 HydrophobicContact CZ3-CG 4.26Å; E434-T438 WeakPolarHBondContact O-CB 3.44Å; E434-T438 PolarHBondContact O-N 2.88Å; E434-T438 PolarHBondContact O-OG1 3.16Å
435I96.3Very high95.4Very high84 Ų8438 Ų3843%0.43121%0.211SC..Hα-helixtrans-67.1-46.8179.3-60-170.7000110.3A431 A433 F437 T438 I439A431-I435 HydrophobicContact CB-CB 4.05Å; A431-I435 HydrophobicContact CB-CD1 4.34Å; A431-I435 HydrophobicContact CB-CG2 3.85Å; A431-I435 VanDerWaalsContact O-CD1 3.3Å; A431-I435 WeakPolarHBondContact O-CD1 3.28Å; A431-I435 WeakPolarHBondContact O-CG1 3.48Å; A433-I435 PolarHBondContact O-N 3.02Å; I435-F437 PolarHBondContact O-N 3.2Å; I435-T438 PolarHBondContact O-N 2.68Å; I435-I439 HydrophobicContact CG2-CD1 3.44Å; I435-I439 VanDerWaalsContact CG2-CD1 3.44Å; I435-I439 HydrophobicContact CG2-CG1 4.09Å; I435-I439 WeakPolarHBondContact O-CB 3.34Å; I435-I439 WeakPolarHBondContact O-CG1 3.49Å; I435-I439 PolarHBondContact O-N 2.89Å
436C96.8Very high95.6Very high0 Ų041.6 Ų41.60%023%0.229CC..Hα-helixtrans-55.8-53.8178.2179.10000112V427 Y428 G432 A433 T438 C440V427-C436 HydrophobicContact CB-CB 4.49Å; V427-C436 HydrophobicContact CG1-CB 3.92Å; Y428-C436 HydrophobicContact CD2-CB 4.4Å; G432-C436 VanDerWaalsContact O-CB 3.31Å; G432-C436 WeakPolarHBondContact O-CB 3.44Å; G432-C436 PolarHBondContact O-N 3.22Å; G432-C436 VanDerWaalsContact O-N 3.07Å; A433-C436 PolarHBondContact O-N 3Å; C436-T438 PolarHBondContact O-N 3.14Å; C436-C440 VanDerWaalsContact O-CB 3.25Å; C436-C440 WeakPolarHBondContact O-CB 3.38Å; C436-C440 PolarHBondContact O-N 2.9Å; C436-C440 PolarHBondContact O-SG 3.49Å; C436-C440 VanDerWaalsContact O-SG 3.39Å
437F97.3Very high95.7Very high1 Ų140 Ų400%0.00422%0.219CC..Hα-helixtrans-68-33.4-178.6-83.5-101000112.7L298 L305 F359 I362 G363 Y428 A433 I435 G441L298-F437 HydrophobicContact CB-CE1 4.27Å; L298-F437 HydrophobicContact CD2-CD1 3.98Å; L298-F437 HydrophobicContact CD2-CD2 4.17Å; L298-F437 HydrophobicContact CD2-CE1 4.1Å; L298-F437 HydrophobicContact CD2-CE2 4.3Å; L298-F437 HydrophobicContact CD2-CG 4.01Å; L298-F437 HydrophobicContact CD2-CZ 4.26Å; L305-F437 HydrophobicContact CB-CE2 4.34Å; L305-F437 HydrophobicContact CD1-CD2 3.85Å; L305-F437 HydrophobicContact CD1-CE1 4.37Å; L305-F437 HydrophobicContact CD1-CE2 3.54Å; L305-F437 HydrophobicContact CD1-CG 4.39Å; L305-F437 HydrophobicContact CD1-CZ 3.83Å; F359-F437 HydrophobicContact CB-CD1 4.41Å; F359-F437 AromaticContact CD1-CD1 3.94Å; F359-F437 HydrophobicContact CD1-CD1 3.94Å; F359-F437 HydrophobicContact CD1-CE1 4.03Å; I362-F437 HydrophobicContact CB-CD1 4.26Å; I362-F437 HydrophobicContact CB-CE1 4.28Å; I362-F437 HydrophobicContact CG2-CD1 3.86Å; I362-F437 HydrophobicContact CG2-CE1 3.45Å; I362-F437 VanDerWaalsContact CG2-CE1 3.45Å; I362-F437 HydrophobicContact CG2-CZ 4.16Å; G363-F437 VanDerWaalsContact CA-CB 3.48Å; Y428-F437 HydrophobicContact CD2-CE2 4.25Å; Y428-F437 HydrophobicContact CE2-CE2 4.22Å; A433-F437 WeakPolarHBondContact O-CB 3.45Å; A433-F437 VanDerWaalsContact O-CD2 3.29Å; A433-F437 WeakPolarHBondContact O-CD2 3.17Å; A433-F437 PolarHBondContact O-N 3.03Å; I435-F437 PolarHBondContact O-N 3.2Å; F437-G441 VanDerWaalsContact O-CA 3.28Å; F437-G441 WeakPolarHBondContact O-CA 3.28Å; F437-G441 PolarHBondContact O-N 3.2Å
438T96.8Very high95.7Very high42 Ų4240.7 Ų40.726%0.25822%0.219SC..Hα-helixtrans-70.3-48177.4-57.90000111.8L360 W364 E434 I435 C436 T442L360-T438 HydrophobicContact CD2-CG2 3.88Å; W364-T438 PolarHBondContact NE1-OG1 2.85Å; E434-T438 WeakPolarHBondContact O-CB 3.44Å; E434-T438 PolarHBondContact O-N 2.88Å; E434-T438 PolarHBondContact O-OG1 3.16Å; I435-T438 PolarHBondContact O-N 2.68Å; C436-T438 PolarHBondContact O-N 3.14Å; T438-T442 WeakPolarHBondContact O-CB 3.46Å; T438-T442 PolarHBondContact O-N 3.14Å; T438-T442 PolarHBondContact O-OG1 3.23Å
439I94.6Very high95.7Very high72 Ų7245.8 Ų45.837%0.36925%0.245SC..Hα-helixtrans-67.1-55-179.2-67.2178.4000110.3I435 G441 T442 F443I435-I439 HydrophobicContact CG2-CD1 3.44Å; I435-I439 VanDerWaalsContact CG2-CD1 3.44Å; I435-I439 HydrophobicContact CG2-CG1 4.09Å; I435-I439 WeakPolarHBondContact O-CB 3.34Å; I435-I439 WeakPolarHBondContact O-CG1 3.49Å; I435-I439 PolarHBondContact O-N 2.89Å; I439-G441 VanDerWaalsContact C-N 3.29Å; I439-G441 PolarHBondContact O-N 3.48Å; I439-T442 PolarHBondContact O-N 3.36Å; I439-F443 HydrophobicContact CG2-CD2 4.3Å; I439-F443 HydrophobicContact CG2-CE1 4.16Å; I439-F443 HydrophobicContact CG2-CE2 3.9Å; I439-F443 HydrophobicContact CG2-CZ 3.83Å; I439-F443 WeakPolarHBondContact O-CG 3.3Å; I439-F443 PolarHBondContact O-N 2.96Å
440C93.3Very high95.7Very high4 Ų446.4 Ų46.43%0.02725%0.25CS..Hα-helixtrans-64-36.7-179.4-650000111.6L294 L298 C436 F443 F444L294-C440 HydrophobicContact CD2-CB 4.27Å; L298-C440 HydrophobicContact CD1-CB 3.76Å; L298-C440 HydrophobicContact CD2-CB 3.75Å; L298-C440 HydrophobicContact CG-CB 3.85Å; C436-C440 VanDerWaalsContact O-CB 3.25Å; C436-C440 WeakPolarHBondContact O-CB 3.38Å; C436-C440 PolarHBondContact O-N 2.9Å; C436-C440 PolarHBondContact O-SG 3.49Å; C436-C440 VanDerWaalsContact O-SG 3.39Å; C440-F443 PolarHBondContact O-N 2.94Å; C440-F444 WeakPolarHBondContact O-CD2 3.3Å
441G93.4Very high95.6Very high0 Ų041 Ų410%022%0.223CC..Hα-helixtrans-60.5-44.2173.300000112.6F437 I439 F444F437-G441 VanDerWaalsContact O-CA 3.28Å; F437-G441 WeakPolarHBondContact O-CA 3.28Å; F437-G441 PolarHBondContact O-N 3.2Å; I439-G441 VanDerWaalsContact C-N 3.29Å; I439-G441 PolarHBondContact O-N 3.48Å; G441-F444 WeakPolarHBondContact O-CB 3.5Å; G441-F444 WeakPolarHBondContact O-CD2 3.28Å; G441-F444 PolarHBondContact O-N 3.45Å
442T94.4Very high95.3Very high58 Ų5841.2 Ų41.236%0.35623%0.228SC..Hα-helixtrans-70.5-32.7178.7-55.60000112.1T438 I439 F444 L445T438-T442 WeakPolarHBondContact O-CB 3.46Å; T438-T442 PolarHBondContact O-N 3.14Å; T438-T442 PolarHBondContact O-OG1 3.23Å; I439-T442 PolarHBondContact O-N 3.36Å; T442-F444 PolarHBondContact O-N 3.46Å; T442-F444 VanDerWaalsContact O-N 3.1Å; T442-L445 HydrophobicContact CG2-CD1 4Å; T442-L445 WeakPolarHBondContact O-CB 3.4Å; T442-L445 WeakPolarHBondContact O-CG 3.48Å; T442-L445 PolarHBondContact O-N 3.01Å
443F96.4Very high95Very high104 Ų10443.5 Ų43.546%0.45624%0.24SC..Hα-helixtrans-65-11.8177.6-762.9000114.1L294 I439 C440 L445 I446 P447L294-F443 VanDerWaalsContact CD1-C 3.45Å; L294-F443 HydrophobicContact CD1-CB 3.76Å; L294-F443 HydrophobicContact CD2-CB 3.97Å; I439-F443 HydrophobicContact CG2-CD2 4.3Å; I439-F443 HydrophobicContact CG2-CE1 4.16Å; I439-F443 HydrophobicContact CG2-CE2 3.9Å; I439-F443 HydrophobicContact CG2-CZ 3.83Å; I439-F443 WeakPolarHBondContact O-CG 3.3Å; I439-F443 PolarHBondContact O-N 2.96Å; C440-F443 PolarHBondContact O-N 2.94Å; F443-L445 PolarHBondContact O-N 3.3Å; F443-I446 HydrophobicContact CB-CD1 4.28Å; F443-I446 HydrophobicContact CG-CD1 4.32Å; F443-I446 WeakPolarHBondContact O-CB 3.38Å; F443-I446 WeakPolarHBondContact O-CG1 3.38Å; F443-I446 PolarHBondContact O-N 3.46Å; F443-P447 WeakPolarHBondContact O-CD 3.43Å
444F96.1Very high94.6Very high0 Ų044 Ų440%024%0.243CC..THydrogen-bonded Turntrans-61.7-15.6166-80.2-77.6000113.4Y291 L294 F295 L298 I352 L355 I356 F359 C440 G441 T442 I446 P447 F448Y291-F444 HydrophobicContact CD2-CD1 4.08Å; Y291-F444 AromaticContact CD2-CE1 3.6Å; Y291-F444 HydrophobicContact CD2-CE1 3.6Å; Y291-F444 AromaticContact CE2-CE1 3.96Å; Y291-F444 HydrophobicContact CE2-CE1 3.96Å; Y291-F444 HydrophobicContact CG-CE1 4.46Å; L294-F444 HydrophobicContact CB-CD2 4.32Å; L294-F444 HydrophobicContact CB-CE1 3.95Å; L294-F444 HydrophobicContact CB-CE2 3.69Å; L294-F444 HydrophobicContact CB-CZ 3.5Å; L294-F444 VanDerWaalsContact CB-CZ 3.5Å; L294-F444 HydrophobicContact CD1-CD1 4.23Å; L294-F444 HydrophobicContact CD1-CD2 4.18Å; L294-F444 HydrophobicContact CD1-CE1 4.42Å; L294-F444 HydrophobicContact CD1-CE2 4.38Å; L294-F444 HydrophobicContact CD1-CG 4.11Å; F295-F444 HydrophobicContact CB-CE1 4.46Å; F295-F444 HydrophobicContact CB-CZ 4.12Å; L298-F444 HydrophobicContact CD1-CE2 4.21Å; I352-F444 HydrophobicContact CG2-CB 3.98Å; I352-F444 WeakPolarHBondContact CG2-O 3.48Å; L355-F444 HydrophobicContact CB-CG 4.49Å; L355-F444 HydrophobicContact CD1-CD1 4.06Å; L355-F444 HydrophobicContact CD1-CE1 3.87Å; L355-F444 HydrophobicContact CD1-CZ 4.27Å; I356-F444 HydrophobicContact CG1-CB 4.32Å; F359-F444 HydrophobicContact CD2-CD2 4.13Å; F359-F444 AromaticContact CD2-CE2 3.63Å; F359-F444 HydrophobicContact CD2-CE2 3.63Å; F359-F444 HydrophobicContact CD2-CZ 4.43Å; F359-F444 HydrophobicContact CE2-CD2 4.18Å; F359-F444 AromaticContact CE2-CE2 3.32Å; F359-F444 HydrophobicContact CE2-CE2 3.32Å; F359-F444 AromaticContact CE2-CZ 3.68Å; F359-F444 HydrophobicContact CE2-CZ 3.68Å; F359-F444 HydrophobicContact CZ-CE2 4.31Å; F359-F444 HydrophobicContact CZ-CZ 4.46Å; C440-F444 WeakPolarHBondContact O-CD2 3.3Å; G441-F444 WeakPolarHBondContact O-CB 3.5Å; G441-F444 WeakPolarHBondContact O-CD2 3.28Å; G441-F444 PolarHBondContact O-N 3.45Å; T442-F444 PolarHBondContact O-N 3.46Å; T442-F444 VanDerWaalsContact O-N 3.1Å; F444-I446 PolarHBondContact O-N 2.85Å; F444-P447 HydrophobicContact CD1-CG 4.49Å; F444-P447 WeakPolarHBondContact O-CD 3.47Å; F444-P447 VanDerWaalsContact O-CG 3.26Å; F444-P447 WeakPolarHBondContact O-CG 3.43Å; F444-F448 PolarHBondContact O-N 3.28Å
445L96.4Very high93.6Very high66 Ų6647 Ų4735%0.34626%0.255SS..Hα-helixtrans-61.7-28.9168.8-71.4172.9000112.6M353 I356 T442 F443 F448 I449M353-L445 HydrophobicContact SD-CD2 4.08Å; I356-L445 HydrophobicContact CD1-CD2 3.53Å; I356-L445 HydrophobicContact CD1-CG 3.76Å; T442-L445 HydrophobicContact CG2-CD1 4Å; T442-L445 WeakPolarHBondContact O-CB 3.4Å; T442-L445 WeakPolarHBondContact O-CG 3.48Å; T442-L445 PolarHBondContact O-N 3.01Å; F443-L445 PolarHBondContact O-N 3.3Å; L445-F448 WeakPolarHBondContact O-CB 3.33Å; L445-F448 PolarHBondContact O-N 3.07Å; L445-I449 VanDerWaalsContact O-CG1 3.24Å; L445-I449 WeakPolarHBondContact O-CG1 3.3Å; L445-I449 PolarHBondContact O-N 3.28Å
446I96.9Very high91.9Very high76 Ų7648.9 Ų48.939%0.3926%0.262SS..Hα-helixtrans-61.6-57.8179.7-58.9171000111.2I290 F443 F444 F448 I449 L450I290-I446 HydrophobicContact CD1-CG2 3.79Å; F443-I446 HydrophobicContact CB-CD1 4.28Å; F443-I446 HydrophobicContact CG-CD1 4.32Å; F443-I446 WeakPolarHBondContact O-CB 3.38Å; F443-I446 WeakPolarHBondContact O-CG1 3.38Å; F443-I446 PolarHBondContact O-N 3.46Å; F444-I446 PolarHBondContact O-N 2.85Å; I446-F448 PolarHBondContact O-N 2.83Å; I446-I449 PolarHBondContact O-N 2.92Å; I446-L450 HydrophobicContact CG2-CD1 4.14Å; I446-L450 HydrophobicContact CG2-CG 4.49Å; I446-L450 WeakPolarHBondContact O-CG 3.38Å; I446-L450 PolarHBondContact O-N 3.04Å
447P96.3Very high89.9Confident1 Ų154.1 Ų54.11%0.00629%0.286CS..Hα-helixtrans-62.9-29.917624.4-33.2000112.3A287 I290 I352 F443 F444 L451A287-P447 HydrophobicContact CB-CB 4.16Å; I290-P447 HydrophobicContact CG2-CG 4.23Å; I352-P447 HydrophobicContact CD1-CB 4.18Å; I352-P447 HydrophobicContact CD1-CG 4.38Å; F443-P447 WeakPolarHBondContact O-CD 3.43Å; F444-P447 HydrophobicContact CD1-CG 4.49Å; F444-P447 WeakPolarHBondContact O-CD 3.47Å; F444-P447 VanDerWaalsContact O-CG 3.26Å; F444-P447 WeakPolarHBondContact O-CG 3.43Å; P447-L451 WeakPolarHBondContact O-CB 3.49Å; P447-L451 WeakPolarHBondContact O-CG 3.35Å; P447-L451 PolarHBondContact O-N 3.47Å
448F95.8Very high87.2Confident55 Ų5559.3 Ų59.324%0.24132%0.318CS..Hα-helixtrans-60.9-45.1173174.3-92.1000112.8K349 I352 M353 F444 L445 I446 G452K349-F448 HydrophobicContact CB-CD2 3.9Å; K349-F448 HydrophobicContact CB-CE2 3.82Å; K349-F448 HydrophobicContact CD-CE2 4.42Å; K349-F448 HydrophobicContact CG-CD2 4.11Å; K349-F448 HydrophobicContact CG-CE2 4.27Å; I352-F448 HydrophobicContact CG2-CB 3.88Å; M353-F448 HydrophobicContact CG-CD2 3.61Å; M353-F448 HydrophobicContact CG-CE2 3.4Å; M353-F448 HydrophobicContact CG-CG 4.46Å; M353-F448 HydrophobicContact CG-CZ 4.13Å; M353-F448 HydrophobicContact SD-CD1 4.33Å; M353-F448 HydrophobicContact SD-CD2 3.81Å; M353-F448 HydrophobicContact SD-CE1 4.32Å; M353-F448 HydrophobicContact SD-CE2 3.78Å; M353-F448 HydrophobicContact SD-CG 4.08Å; M353-F448 HydrophobicContact SD-CZ 4.05Å; F444-F448 PolarHBondContact O-N 3.28Å; L445-F448 WeakPolarHBondContact O-CB 3.33Å; L445-F448 PolarHBondContact O-N 3.07Å; I446-F448 PolarHBondContact O-N 2.83Å; F448-G452 PolarHBondContact O-N 3.07Å
449I96.2Very high84.4Confident111 Ų11167.6 Ų67.657%0.56935%0.351SS*.Hα-helixtrans-67.3-47.3178.3-67.4163.5000110L445 I446 L451 G452L445-I449 VanDerWaalsContact O-CG1 3.24Å; L445-I449 WeakPolarHBondContact O-CG1 3.3Å; L445-I449 PolarHBondContact O-N 3.28Å; I446-I449 PolarHBondContact O-N 2.92Å; I449-L451 VanDerWaalsContact C-N 3.29Å; I449-L451 PolarHBondContact O-N 3.05Å; I449-G452 WeakPolarHBondContact O-CA 3.42Å; I449-G452 PolarHBondContact O-N 3.04Å
450L95.1Very high81.2Confident42 Ų4272.2 Ų72.222%0.2237%0.371CS..Hα-helixtrans-55.5-44.1178.3-71.5175.5000112I283 L286 A287 I290 I446 G452 S453I283-L450 HydrophobicContact CG2-CB 4.26Å; I283-L450 VanDerWaalsContact CG2-O 3.22Å; I283-L450 WeakPolarHBondContact CG2-O 3.29Å; L286-L450 HydrophobicContact CD2-CD1 3.85Å; L286-L450 HydrophobicContact CD2-CD2 4.38Å; L286-L450 HydrophobicContact CG-CD1 3.92Å; A287-L450 HydrophobicContact CB-CB 4.45Å; I290-L450 HydrophobicContact CD1-CD1 3.81Å; I446-L450 HydrophobicContact CG2-CD1 4.14Å; I446-L450 HydrophobicContact CG2-CG 4.49Å; I446-L450 WeakPolarHBondContact O-CG 3.38Å; I446-L450 PolarHBondContact O-N 3.04Å; L450-G452 PolarHBondContact O-N 3.39Å; L450-S453 WeakPolarHBondContact O-CB 3.45Å; L450-S453 PolarHBondContact O-N 3.46Å
451L93.9Very high78.2Confident3 Ų384.5 Ų84.52%0.01643%0.428CS..Hα-helixtrans-67.3-17.1177.6-68.6173000113.5L284 A287 I345 V348 K349 I352 L389 P447 I449 S453 V454L284-L451 HydrophobicContact CD2-CD2 3.82Å; A287-L451 HydrophobicContact CB-CD2 3.87Å; A287-L451 HydrophobicContact CB-CG 3.97Å; I345-L451 HydrophobicContact CD1-CD2 4.24Å; I345-L451 HydrophobicContact CG2-CB 4.4Å; V348-L451 HydrophobicContact CB-CD1 4.36Å; V348-L451 HydrophobicContact CG1-CD1 3.45Å; V348-L451 VanDerWaalsContact CG1-CD1 3.45Å; K349-L451 HydrophobicContact CD-CB 4.32Å; K349-L451 HydrophobicContact CG-CB 4.08Å; K349-L451 HydrophobicContact CG-CD1 4.46Å; I352-L451 HydrophobicContact CD1-CD1 3.76Å; L389-L451 HydrophobicContact CD2-CD1 4.41Å; L389-L451 HydrophobicContact CD2-CD2 3.94Å; P447-L451 WeakPolarHBondContact O-CB 3.49Å; P447-L451 WeakPolarHBondContact O-CG 3.35Å; P447-L451 PolarHBondContact O-N 3.47Å; I449-L451 VanDerWaalsContact C-N 3.29Å; I449-L451 PolarHBondContact O-N 3.05Å; L451-S453 VanDerWaalsContact C-N 3.28Å; L451-V454 HydrophobicContact CD2-CG2 4.33Å
452G89.5Confident77.4Confident46 Ų4688.7 Ų88.747%0.47445%0.449SS..Hα-helixtrans-68.2-26.2170.300000113.7F448 I449 L450 V454F448-G452 PolarHBondContact O-N 3.07Å; I449-G452 WeakPolarHBondContact O-CA 3.42Å; I449-G452 PolarHBondContact O-N 3.04Å; L450-G452 PolarHBondContact O-N 3.39Å; G452-V454 VanDerWaalsContact C-N 3.35Å
453S88.1Confident76.5Confident73 Ų7390.3 Ų90.351%0.5145%0.454SS..THydrogen-bonded Turntrans-85.4-7.7-179.3-55.60000113.5L450 L451 K455L450-S453 WeakPolarHBondContact O-CB 3.45Å; L450-S453 PolarHBondContact O-N 3.46Å; L451-S453 VanDerWaalsContact C-N 3.28Å; S453-K455 PolarHBondContact O-N 3.19Å; S453-K455 VanDerWaalsContact O-N 3.15Å
454V86.8Confident75.4Confident18 Ų1889.6 Ų89.611%0.10945%0.454CS..  trans-71.4108.3177.9179.90000108.9N280 I283 L284 L451 G452 Q456N280-V454 HydrophobicContact CB-CG1 4.47Å; I283-V454 HydrophobicContact CB-CG2 4.31Å; I283-V454 HydrophobicContact CG2-CG2 3.62Å; L284-V454 HydrophobicContact CD2-CG2 4.24Å; L284-V454 HydrophobicContact CG-CG2 4.38Å; L451-V454 HydrophobicContact CD2-CG2 4.33Å; G452-V454 VanDerWaalsContact C-N 3.35Å; V454-Q456 PolarHBondContact O-N 3.28Å
455K74.7Confident74.2Confident132 Ų13294.8 Ų94.857%0.57448%0.48SS*.  trans-73.1117176.4-66.9-179.7-179177.50108.3N280 S453 Q457N280-K455 PolarHBondContact ND2-O 2.81Å; N280-K455 PolarHBondContact OD1-N 2.95Å; S453-K455 PolarHBondContact O-N 3.19Å; S453-K455 VanDerWaalsContact O-N 3.15Å; K455-Q457 PolarHBondContact O-N 3.16Å
456Q62Low72.8Confident123 Ų12396.6 Ų96.658%0.57549%0.489SS*.  trans-56.1139176.6-75.6-174.4-30.900110.1G342 V454 T458G342-Q456 PolarHBondContact O-NE2 3.34Å; V454-Q456 PolarHBondContact O-N 3.28Å; Q456-T458 PolarHBondContact O-N 3.06Å; Q456-T458 VanDerWaalsContact O-N 3.16Å
457Q55Low71.2Confident110 Ų11098 Ų9851%0.51450%0.495SS..  trans-65.2111.8166.6-72.9-178.4-27.900107N277 K455N277-Q457 PolarHBondContact OD1-NE2 3.15Å; N277-Q457 VanDerWaalsContact OD1-NE2 3.16Å; K455-Q457 PolarHBondContact O-N 3.16Å
458T39.9Very low69.4Low110 Ų110104.9 Ų104.968%0.67553%0.53SS*.  trans-57.3137.9161.98.90000107.2Q456 E460Q456-T458 PolarHBondContact O-N 3.06Å; Q456-T458 VanDerWaalsContact O-N 3.16Å; T458-E460 PolarHBondContact O-N 3.18Å
459K36.8Very low67.4Low216 Ų216108.8 Ų108.894%0.93955%0.553SS**SBendtrans-66.917.3-171.5-108.5-177.8177.1-174.80115
460E27.5Very low65Low168 Ų168108.6 Ų108.679%0.78555%0.551SS**  trans-124.684.6-172.5-69.5176170.900108.2T458T458-E460 PolarHBondContact O-N 3.18Å
461E30.7Very low62.3Low262 Ų262114.6 Ų114.6100%1.22458%0.581SS**  trans-167.70153.2-105.4169.9-15100109.5

Retrieved 461 of 461 residues in 206.8 ms (Link to these results)

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