A0A093J170_STRCA Loading...

Kinesin-like protein

AlphaFold DB , UniProt , Accession A0A093J170, Species STRCA (Struthio camelus australis), Gene n/a, Length 739 aa.

Structure Viewer
Loading PAE data...
(Predicted Aligned Error values between residue pairs)
Error loading PAE data: please refresh the page.

Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M31.6Very low63.8Low246 Ų246110.7 Ų110.7100%1.21259%0.587SS**  0128.20-55.3-177.2-154.500108K3M1-K3 PolarHBondContact O-N 3.43Å
2S33.7Very low66.5Low115 Ų115101.5 Ų101.580%0.80454%0.538SS*.  trans-74.2123.2171.838.40000109.3L4S2-L4 PolarHBondContact O-N 3.32Å
3K37.3Very low68.9Low207 Ų20793.8 Ų93.890%0.950%0.497SS*.  trans-59113.2163.5-79.5-177.1176178.60106.9M1 K5M1-K3 PolarHBondContact O-N 3.43Å; K3-K5 PolarHBondContact O-N 2.97Å
4L38.9Very low71Confident167 Ų16787.2 Ų87.287%0.87446%0.462SS*.  trans-54114.8169.4-82.6147.9000107.4S2 S6S2-L4 PolarHBondContact O-N 3.32Å; L4-S6 VanDerWaalsContact C-N 3.33Å; L4-S6 PolarHBondContact O-N 3.3Å
5K47.2Very low72.8Confident165 Ų16582.5 Ų82.572%0.71744%0.436SS*.  trans-66.496.1173.4-73.4176.9177.4172.10106.9K3 S7K3-K5 PolarHBondContact O-N 2.97Å; K5-S7 PolarHBondContact O-N 2.95Å
6S62Low74.3Confident100 Ų10077.3 Ų77.370%0.69941%0.408SS*.  trans-62.6109.4179.755.70000109.4L4L4-S6 VanDerWaalsContact C-N 3.33Å; L4-S6 PolarHBondContact O-N 3.3Å
7S78.9Confident75.5Confident73 Ų7375 Ų7551%0.5139%0.393SS..PPolyproline II helixtrans-71.2130.4165.434.90000109.4K5 N342K5-S7 PolarHBondContact O-N 2.95Å; S7-N342 VanDerWaalsContact CA-O 3.31Å; S7-N342 WeakPolarHBondContact CA-O 3.42Å
8E89.4Confident76.6Confident47 Ų4775.1 Ų75.122%0.2240%0.399CS..EExtended strand (participates in β ladder)trans-102.5136173.2-170171.8176.700108.1R11 K310 N342 P344E8-R11 IonicContact OE1-CZ 3.41Å; E8-R11 IonicContact OE1-NE 2.68Å; E8-R11 PolarHBondContact OE1-NE 2.73Å; E8-R11 IonicContact OE1-NH2 3.42Å; E8-R11 PolarHBondContact OE1-NH2 2.8Å; E8-K310 WeakPolarHBondContact OE2-CD 3.39Å; E8-K310 WeakPolarHBondContact OE2-CE 3.27Å; E8-K310 WeakPolarHBondContact OE2-CG 3.26Å; E8-N342 PolarHBondContact N-O 3.33Å; E8-N342 PolarHBondContact O-N 2.92Å; E8-P344 HydrophobicContact CB-CG 4.05Å
9S92.6Very high77.5Confident45 Ų4573.1 Ų73.132%0.31539%0.387SS..EExtended strand (participates in β ladder)trans-72.8148.8173.9-45.40000110.2R11 I340 K341S9-R11 PolarHBondContact O-N 3.2Å; S9-I340 CarbonylContact C-O 3.19Å; S9-I340 VanDerWaalsContact CA-O 3.28Å; S9-I340 WeakPolarHBondContact CA-O 3.42Å; S9-K341 PolarHBondContact OG-NZ 3.4Å
10V94.4Very high78Confident1 Ų172.3 Ų72.31%0.00638%0.383CS..PPolyproline II helixtrans-60.8124.4163.5175.30000108.2V12 T311 K338 I340V10-V12 HydrophobicContact CG1-CG2 4.39Å; V10-T311 HydrophobicContact CG1-CG2 4.07Å; V10-K338 WeakPolarHBondContact O-CA 3.43Å; V10-I340 HydrophobicContact CB-CB 4.28Å; V10-I340 HydrophobicContact CG2-CB 3.72Å; V10-I340 HydrophobicContact CG2-CD1 4.48Å; V10-I340 HydrophobicContact CG2-CG2 3.75Å; V10-I340 PolarHBondContact N-O 2.88Å
11R95.6Very high78.6Confident52 Ų5273.7 Ų73.720%0.19640%0.399CS..EExtended strand (participates in β ladder)trans-81136.6177.7-55.8-176.2-162.6177.64.1109E8 S9 D60 T311 V312 M313E8-R11 IonicContact OE1-CZ 3.41Å; E8-R11 IonicContact OE1-NE 2.68Å; E8-R11 PolarHBondContact OE1-NE 2.73Å; E8-R11 IonicContact OE1-NH2 3.42Å; E8-R11 PolarHBondContact OE1-NH2 2.8Å; S9-R11 PolarHBondContact O-N 3.2Å; R11-D60 WeakPolarHBondContact CA-OD2 3.39Å; R11-T311 PolarHBondContact N-O 3.3Å; R11-V312 HydrophobicContact CB-CG2 4.38Å; R11-V312 CarbonylContact O-C 3.24Å; R11-V312 WeakPolarHBondContact O-CA 3.42Å; R11-M313 PolarHBondContact O-N 3.18Å
12V96.9Very high81.2Confident0 Ų070.4 Ų70.40%038%0.378CS..EExtended strand (participates in β ladder)trans-128.2123.6-176.6-177.10000109.3V10 F59 D60 M313 A334 A337 K338V10-V12 HydrophobicContact CG1-CG2 4.39Å; V12-F59 HydrophobicContact CB-CD1 4.3Å; V12-F59 HydrophobicContact CG1-CD1 3.78Å; V12-F59 HydrophobicContact CG1-CE1 4.15Å; V12-D60 PolarHBondContact N-OD2 3.14Å; V12-D60 PolarHBondContact O-N 3.18Å; V12-M313 HydrophobicContact CG1-CB 4.39Å; V12-M313 HydrophobicContact CG1-CG 4.46Å; V12-M313 HydrophobicContact CG1-SD 4.26Å; V12-M313 HydrophobicContact CG2-CB 4.14Å; V12-A334 HydrophobicContact CG1-CB 3.72Å; V12-A337 HydrophobicContact CG2-CB 4.1Å; V12-K338 HydrophobicContact CB-CB 4.04Å; V12-K338 HydrophobicContact CG2-CB 3.58Å
13V97.3Very high83.9Confident2 Ų265.2 Ų65.21%0.01234%0.341CS..EExtended strand (participates in β ladder)trans-120.7141.7175.3-56.10000110.9A61 Y63 T76 M313 V314 A315V13-A61 VanDerWaalsContact CA-O 3.24Å; V13-A61 WeakPolarHBondContact CA-O 3.48Å; V13-A61 HydrophobicContact CB-CB 4.46Å; V13-A61 WeakPolarHBondContact CB-O 3.38Å; V13-A61 HydrophobicContact CG1-CB 3.82Å; V13-Y63 HydrophobicContact CB-CD2 4.4Å; V13-Y63 HydrophobicContact CB-CE2 4.01Å; V13-Y63 HydrophobicContact CG1-CE2 4.33Å; V13-Y63 HydrophobicContact CG2-CE2 4.32Å; V13-T76 HydrophobicContact CG1-CG2 3.71Å; V13-T76 HydrophobicContact CG2-CG2 4.11Å; V13-M313 PolarHBondContact N-O 2.69Å; V13-V314 HydrophobicContact CG2-CB 4.32Å; V13-V314 HydrophobicContact CG2-CG1 4.18Å; V13-V314 HydrophobicContact CG2-CG2 3.97Å; V13-V314 WeakPolarHBondContact O-CA 3.21Å; V13-A315 PolarHBondContact O-N 2.65Å
14V98.1Very high86.5Confident1 Ų161.8 Ų61.81%0.00633%0.326CS..EExtended strand (participates in β ladder)trans-104136.5176.5-178.30000110.2V41 F59 A61 V62 Y63 A315 I317 L331V14-V41 HydrophobicContact CB-CG2 4.01Å; V14-V41 HydrophobicContact CG1-CG2 3.95Å; V14-V41 HydrophobicContact CG2-CG2 4.3Å; V14-F59 HydrophobicContact CB-CD2 4.42Å; V14-F59 HydrophobicContact CG2-CD1 4Å; V14-F59 HydrophobicContact CG2-CD2 3.4Å; V14-F59 VanDerWaalsContact CG2-CD2 3.4Å; V14-F59 HydrophobicContact CG2-CE1 4.01Å; V14-F59 HydrophobicContact CG2-CE2 3.4Å; V14-F59 VanDerWaalsContact CG2-CE2 3.4Å; V14-F59 HydrophobicContact CG2-CG 3.7Å; V14-F59 HydrophobicContact CG2-CZ 3.72Å; V14-A61 PolarHBondContact N-O 3.16Å; V14-A61 VanDerWaalsContact N-O 3.16Å; V14-V62 HydrophobicContact CB-CG1 4.31Å; V14-V62 CarbonylContact O-C 3.6Å; V14-V62 WeakPolarHBondContact O-CA 3.3Å; V14-Y63 PolarHBondContact O-N 3.47Å; V14-A315 CarbonylContact C-O 3.6Å; V14-A315 WeakPolarHBondContact CA-O 3.27Å; V14-A315 HydrophobicContact CG2-CB 4.13Å; V14-I317 HydrophobicContact CG1-CD1 3.61Å; V14-I317 HydrophobicContact CG1-CG1 3.87Å; V14-L331 HydrophobicContact CG1-CD2 3.97Å; V14-L331 HydrophobicContact CG2-CD2 3.77Å
15R97.8Very high89.1Confident16 Ų1657.8 Ų57.86%0.0632%0.317CS..EExtended strand (participates in β ladder)trans-124.5113.3174.1-170.4-177.1-165.9177.312.9111.2T105 V314 A315 N316 I317R15-T105 PolarHBondContact NH1-OG1 3.5Å; R15-V314 HydrophobicContact CB-CG1 4.4Å; R15-A315 PolarHBondContact N-O 2.84Å; R15-N316 WeakPolarHBondContact O-CA 3.29Å; R15-I317 PolarHBondContact O-N 2.72Å
16C97.4Very high91.1Very high0 Ų052.2 Ų52.20%030%0.302CS..EExtended strand (participates in β ladder)trans-93.3116.6173.4-169.20000110.2V34 Y63 D64 W65 I317C16-V34 HydrophobicContact CB-CG2 3.87Å; C16-Y63 PolarHBondContact N-O 3.17Å; C16-D64 CarbonylContact O-C 3.53Å; C16-D64 VanDerWaalsContact O-C 3.24Å; C16-W65 WeakPolarHBondContact O-CA 3.41Å; C16-W65 PolarHBondContact O-N 2.73Å; C16-I317 HydrophobicContact CB-CD1 4.2Å; C16-I317 HydrophobicContact CB-CG1 3.91Å
17R95.3Very high92.5Very high38 Ų3852.5 Ų52.514%0.14330%0.304CS..PPolyproline II helixtrans-75.1162.4177.965.9152.2173.272.64.2112.5N20 E23 G99 T100 I317 P319R17-N20 PolarHBondContact NH2-ND2 3Å; R17-E23 IonicContact CZ-OE1 2.66Å; R17-E23 IonicContact CZ-OE2 3.05Å; R17-E23 IonicContact NH1-OE1 2.75Å; R17-E23 PolarHBondContact NH1-OE1 3.1Å; R17-E23 IonicContact NH1-OE2 2.82Å; R17-E23 PolarHBondContact NH1-OE2 3.27Å; R17-E23 IonicContact NH2-OE1 3.19Å; R17-E23 PolarHBondContact NH2-OE1 2.9Å; R17-E23 IonicContact NH2-OE2 3.51Å; R17-G99 PolarHBondContact NE-O 3.45Å; R17-G99 PolarHBondContact NH2-O 2.9Å; R17-T100 WeakPolarHBondContact CG-O 3.45Å; R17-I317 PolarHBondContact N-O 2.9Å; R17-P319 WeakPolarHBondContact O-CD 3.3Å; R17-P319 WeakPolarHBondContact O-CG 3.47Å
18P95.1Very high93.2Very high77 Ų7753 Ų5350%0.530%0.295SS..PPolyproline II helixtrans-54151.4164.1-24.132.6000112.9N20 W65P18-N20 PolarHBondContact O-N 3.43Å; P18-W65 HydrophobicContact CB-CB 4.31Å; P18-W65 HydrophobicContact CG-CB 4.06Å; P18-W65 WeakPolarHBondContact CG-O 3.26Å
19M92.4Very high93.2Very high37 Ų3756.6 Ų56.618%0.18231%0.312CS..PPolyproline II helixtrans-67.1127.7170.8-171.1178.5-100.700109.7E23 K24 Y28 K30 P319 A320M19-E23 WeakPolarHBondContact CA-OE2 3.37Å; M19-E23 HydrophobicContact CG-CB 3.51Å; M19-E23 HydrophobicContact CG-CG 4.48Å; M19-E23 WeakPolarHBondContact CG-OE2 3.27Å; M19-E23 HydrophobicContact SD-CB 4.3Å; M19-K24 HydrophobicContact CB-CG 4.43Å; M19-K24 HydrophobicContact CG-CG 3.95Å; M19-K24 VanDerWaalsContact O-CE 3.25Å; M19-K24 WeakPolarHBondContact O-CE 3.34Å; M19-K24 HydrophobicContact SD-CG 3.95Å; M19-Y28 WeakPolarHBondContact CE-O 3.48Å; M19-K30 HydrophobicContact CE-CB 4.4Å; M19-P319 HydrophobicContact CB-CG 3.84Å; M19-P319 HydrophobicContact CG-CG 4.46Å; M19-A320 HydrophobicContact CE-CB 3.79Å
20N89.1Confident93.2Very high56 Ų5659.6 Ų59.630%0.29932%0.319SS..PPolyproline II helixtrans-81.9167.4-172.976.847.2000111.9R17 P18 K22 E23 K24R17-N20 PolarHBondContact NH2-ND2 3Å; P18-N20 PolarHBondContact O-N 3.43Å; N20-K22 VanDerWaalsContact C-N 3.3Å; N20-K22 PolarHBondContact O-N 3.2Å; N20-K22 WeakPolarHBondContact OD1-CA 3.36Å; N20-K22 WeakPolarHBondContact OD1-CB 3.4Å; N20-K22 PolarHBondContact OD1-N 3.5Å; N20-E23 PolarHBondContact N-OE2 2.85Å; N20-E23 PolarHBondContact ND2-OE1 3.2Å; N20-E23 PolarHBondContact ND2-OE2 3.24Å; N20-E23 PolarHBondContact O-N 2.91Å; N20-E23 WeakPolarHBondContact OD1-CG 3.4Å; N20-E23 PolarHBondContact OD1-N 3.24Å; N20-K24 WeakPolarHBondContact O-CG 3.47Å; N20-K24 PolarHBondContact O-N 2.92Å
21S88.9Confident93.2Very high103 Ų10360 Ų6072%0.7232%0.322SS*.Hα-helixtrans-62.9-31.9-175.9-48.80000113.8A25S21-A25 VanDerWaalsContact O-CB 3.27Å; S21-A25 WeakPolarHBondContact O-CB 3.01Å; S21-A25 PolarHBondContact O-N 3.21Å
22K87.6Confident93.1Very high176 Ų17657.7 Ų57.777%0.76531%0.313SS*.Hα-helixtrans-70.7-42.3176.2-64.1-177.7178179.50111.1N20 A25 A26N20-K22 VanDerWaalsContact C-N 3.3Å; N20-K22 PolarHBondContact O-N 3.2Å; N20-K22 WeakPolarHBondContact OD1-CA 3.36Å; N20-K22 WeakPolarHBondContact OD1-CB 3.4Å; N20-K22 PolarHBondContact OD1-N 3.5Å; K22-A25 PolarHBondContact O-N 3.37Å; K22-A26 VanDerWaalsContact O-CB 3.29Å; K22-A26 WeakPolarHBondContact O-CB 3.44Å; K22-A26 PolarHBondContact O-N 3.07Å
23E90.1Very high93Very high7 Ų762.6 Ų62.63%0.03334%0.34CS..Hα-helixtrans-64.1-41176.8-69.1165.4163.700112R17 M19 N20 S27 Y28 A320 N323R17-E23 IonicContact CZ-OE1 2.66Å; R17-E23 IonicContact CZ-OE2 3.05Å; R17-E23 IonicContact NH1-OE1 2.75Å; R17-E23 PolarHBondContact NH1-OE1 3.1Å; R17-E23 IonicContact NH1-OE2 2.82Å; R17-E23 PolarHBondContact NH1-OE2 3.27Å; R17-E23 IonicContact NH2-OE1 3.19Å; R17-E23 PolarHBondContact NH2-OE1 2.9Å; R17-E23 IonicContact NH2-OE2 3.51Å; M19-E23 WeakPolarHBondContact CA-OE2 3.37Å; M19-E23 HydrophobicContact CG-CB 3.51Å; M19-E23 HydrophobicContact CG-CG 4.48Å; M19-E23 WeakPolarHBondContact CG-OE2 3.27Å; M19-E23 HydrophobicContact SD-CB 4.3Å; N20-E23 PolarHBondContact N-OE2 2.85Å; N20-E23 PolarHBondContact ND2-OE1 3.2Å; N20-E23 PolarHBondContact ND2-OE2 3.24Å; N20-E23 PolarHBondContact O-N 2.91Å; N20-E23 WeakPolarHBondContact OD1-CG 3.4Å; N20-E23 PolarHBondContact OD1-N 3.24Å; E23-S27 PolarHBondContact O-N 3.43Å; E23-Y28 HydrophobicContact CB-CD2 4.17Å; E23-Y28 HydrophobicContact CG-CD2 4.21Å; E23-Y28 PolarHBondContact O-N 3.2Å; E23-Y28 VanDerWaalsContact O-N 3.12Å; E23-A320 HydrophobicContact CB-CB 4.15Å; E23-A320 HydrophobicContact CG-CB 3.79Å; E23-N323 PolarHBondContact OE1-ND2 3.43Å
24K91.5Very high92.9Very high134 Ų13463.2 Ų63.258%0.58334%0.343SS*.Hα-helixtrans-65.3-45.4173.5-70.7176.2178.4174.30112M19 N20 A26 S27M19-K24 HydrophobicContact CB-CG 4.43Å; M19-K24 HydrophobicContact CG-CG 3.95Å; M19-K24 VanDerWaalsContact O-CE 3.25Å; M19-K24 WeakPolarHBondContact O-CE 3.34Å; M19-K24 HydrophobicContact SD-CG 3.95Å; N20-K24 WeakPolarHBondContact O-CG 3.47Å; N20-K24 PolarHBondContact O-N 2.92Å; K24-A26 VanDerWaalsContact C-N 3.33Å; K24-A26 PolarHBondContact O-N 3.1Å; K24-S27 PolarHBondContact O-N 3.49Å
25A92.9Very high92.7Very high83 Ų8366.2 Ų66.269%0.68636%0.359SS*.Hα-helixtrans-64.3-36.8177.900000112.4S21 K22 S27S21-A25 VanDerWaalsContact O-CB 3.27Å; S21-A25 WeakPolarHBondContact O-CB 3.01Å; S21-A25 PolarHBondContact O-N 3.21Å; K22-A25 PolarHBondContact O-N 3.37Å; A25-S27 PolarHBondContact O-N 2.78Å
26A90.8Very high92.3Very high48 Ų4867.8 Ų67.840%0.39737%0.37SS..THydrogen-bonded Turntrans-751173.400000113.9K22 K24 Y28K22-A26 VanDerWaalsContact O-CB 3.29Å; K22-A26 WeakPolarHBondContact O-CB 3.44Å; K22-A26 PolarHBondContact O-N 3.07Å; K24-A26 VanDerWaalsContact C-N 3.33Å; K24-A26 PolarHBondContact O-N 3.1Å; A26-Y28 HydrophobicContact CB-CD1 4.4Å; A26-Y28 HydrophobicContact CB-CD2 3.9Å; A26-Y28 HydrophobicContact CB-CE1 4.13Å; A26-Y28 HydrophobicContact CB-CE2 3.6Å; A26-Y28 HydrophobicContact CB-CG 4.28Å; A26-Y28 PolarHBondContact O-N 2.97Å
27S91.6Very high91.7Very high106 Ų10675.6 Ų75.674%0.74140%0.404SS*.THydrogen-bonded Turntrans53.534.8-179.2-56.50000114.2E23 K24 A25E23-S27 PolarHBondContact O-N 3.43Å; K24-S27 PolarHBondContact O-N 3.49Å; A25-S27 PolarHBondContact O-N 2.78Å
28Y91.6Very high91.2Very high84 Ų8475 Ų7533%0.32940%0.404SS..  trans-69.3137.7175.9-65.8-40.2000111.4M19 E23 A26 A320 Y322M19-Y28 WeakPolarHBondContact CE-O 3.48Å; E23-Y28 HydrophobicContact CB-CD2 4.17Å; E23-Y28 HydrophobicContact CG-CD2 4.21Å; E23-Y28 PolarHBondContact O-N 3.2Å; E23-Y28 VanDerWaalsContact O-N 3.12Å; A26-Y28 HydrophobicContact CB-CD1 4.4Å; A26-Y28 HydrophobicContact CB-CD2 3.9Å; A26-Y28 HydrophobicContact CB-CE1 4.13Å; A26-Y28 HydrophobicContact CB-CE2 3.6Å; A26-Y28 HydrophobicContact CB-CG 4.28Å; A26-Y28 PolarHBondContact O-N 2.97Å; Y28-A320 HydrophobicContact CD2-CB 4.46Å; Y28-Y322 HydrophobicContact CD2-CG 4.46Å; Y28-Y322 HydrophobicContact CE1-CD2 4.23Å; Y28-Y322 HydrophobicContact CE1-CG 4.37Å; Y28-Y322 HydrophobicContact CE2-CD1 4.36Å; Y28-Y322 HydrophobicContact CE2-CD2 4.28Å; Y28-Y322 AromaticContact CE2-CG 3.81Å; Y28-Y322 HydrophobicContact CE2-CG 3.81Å; Y28-Y322 AromaticContact CZ-CD2 3.76Å; Y28-Y322 AromaticContact CZ-CG 3.77Å; Y28-Y322 WeakPolarHBondContact OH-CD2 3.15Å
29E90.3Very high91Very high123 Ų12371.3 Ų71.358%0.57538%0.38SS*.  trans-68.5153.3174.5-65.1-170.5173.600111.9A320 S321E29-A320 CarbonylContact O-C 3.55Å; E29-A320 WeakPolarHBondContact O-CA 3.29Å; E29-S321 PolarHBondContact N-OG 2.98Å; E29-S321 PolarHBondContact O-N 3.16Å
30K93Very high91Very high108 Ų10872.1 Ų72.147%0.4738%0.383SS..BIsolated β-bridgetrans-86.9112.5169.8177.8177.8179-1750109.5M19 V32 W65 P319M19-K30 HydrophobicContact CE-CB 4.4Å; K30-V32 WeakPolarHBondContact CE-O 3.41Å; K30-W65 VanDerWaalsContact NZ-CE2 3.3Å; K30-W65 VanDerWaalsContact NZ-CE3 3.32Å; K30-P319 WeakPolarHBondContact CA-O 3.45Å; K30-P319 HydrophobicContact CG-CB 4.27Å
31V93.3Very high91.3Very high9 Ų969.5 Ų69.56%0.05537%0.369CS..  trans-105.9-10.6-174.8-63.70000114.3K44 P46 P319 V324V31-K44 WeakPolarHBondContact CB-O 3.31Å; V31-K44 PolarHBondContact O-N 2.65Å; V31-P46 HydrophobicContact CG1-CB 4.33Å; V31-P46 HydrophobicContact CG1-CG 4.22Å; V31-P319 PolarHBondContact N-O 3.17Å; V31-V324 HydrophobicContact CG2-CB 4.24Å; V31-V324 HydrophobicContact CG2-CG2 4.16Å
32V95.1Very high91.5Very high3 Ų365.9 Ų65.92%0.01834%0.344CS..EExtended strand (participates in β ladder)trans-100.3125178.1-174.10000110.1K30 V34 V41 V43 I317 G318 T327K30-V32 WeakPolarHBondContact CE-O 3.41Å; V32-V34 HydrophobicContact CG1-CG2 4.02Å; V32-V41 HydrophobicContact CG1-CG1 3.69Å; V32-V43 HydrophobicContact CG2-CG2 4.37Å; V32-I317 HydrophobicContact CG1-CD1 3.85Å; V32-G318 WeakPolarHBondContact CG2-O 3.41Å; V32-T327 HydrophobicContact CG2-CG2 3.97Å
33N94.2Very high91.7Very high104 Ų10457.6 Ų57.656%0.55631%0.308SS*.EExtended strand (participates in β ladder)trans-109141.5166-166.124.1000109.8S42N33-S42 PolarHBondContact N-O 3.31Å; N33-S42 PolarHBondContact O-N 3.26Å
34V95.4Very high91.7Very high14 Ų1463.1 Ų63.19%0.08533%0.332CS..EExtended strand (participates in β ladder)trans-128.8117.8-175.1-179.20000108.5C16 V32 V36 V62 D64 W65C16-V34 HydrophobicContact CB-CG2 3.87Å; V32-V34 HydrophobicContact CG1-CG2 4.02Å; V34-V36 HydrophobicContact CG1-CG2 4.11Å; V34-V62 HydrophobicContact CG1-CB 3.93Å; V34-V62 HydrophobicContact CG1-CG2 3.53Å; V34-D64 HydrophobicContact CB-CB 4.25Å; V34-D64 HydrophobicContact CG1-CB 4.21Å; V34-W65 HydrophobicContact CB-CZ3 4.4Å; V34-W65 HydrophobicContact CG2-CZ3 4.25Å
35D92.8Very high91.1Very high64 Ų6458.9 Ų58.934%0.34232%0.316SS..EExtended strand (participates in β ladder)trans-100.798.4171.8-166.2-41.9000109.9K37 L38 G39 Q40 V62D35-K37 PolarHBondContact O-N 2.87Å; D35-K37 WeakPolarHBondContact OD1-CA 3.35Å; D35-K37 WeakPolarHBondContact OD1-CB 3.49Å; D35-K37 PolarHBondContact OD1-N 2.97Å; D35-L38 HydrophobicContact CB-CB 4.35Å; D35-L38 PolarHBondContact O-N 3.19Å; D35-L38 PolarHBondContact OD1-N 3.2Å; D35-G39 PolarHBondContact O-N 3.39Å; D35-Q40 HydrophobicContact CB-CB 4.35Å; D35-Q40 PolarHBondContact N-O 3.2Å; D35-Q40 PolarHBondContact O-N 3.41Å; D35-V62 WeakPolarHBondContact O-CG2 3.45Å
36V90.2Very high90.3Very high49 Ų4957.6 Ų57.630%0.29730%0.3SS..THydrogen-bonded Turntrans-67.1-21.7-179.4-178.20000112.6V34 D64 R500V34-V36 HydrophobicContact CG1-CG2 4.11Å; V36-D64 HydrophobicContact CG2-CB 4.1Å; V36-R500 WeakPolarHBondContact O-CD 3.46Å; V36-R500 PolarHBondContact O-NE 2.92Å; V36-R500 VanDerWaalsContact O-NE 3.08Å
37K85.5Confident89.4Confident164 Ų16464 Ų6471%0.71331%0.314SS*.THydrogen-bonded Turntrans-80-44.1177.2-66.1-172.2175.2-169.60111D35 R500D35-K37 PolarHBondContact O-N 2.87Å; D35-K37 WeakPolarHBondContact OD1-CA 3.35Å; D35-K37 WeakPolarHBondContact OD1-CB 3.49Å; D35-K37 PolarHBondContact OD1-N 2.97Å; K37-R500 WeakPolarHBondContact O-CD 3.49Å; K37-R500 VanDerWaalsContact O-CG 3.27Å; K37-R500 WeakPolarHBondContact O-CG 3.38Å
38L84.4Confident88Confident26 Ų2660 Ų6014%0.13629%0.29CS..THydrogen-bonded Turntrans-86.6-7.7-177.7-56.8-174.4000113.7D35 Q40 Q503 Q504 E507D35-L38 HydrophobicContact CB-CB 4.35Å; D35-L38 PolarHBondContact O-N 3.19Å; D35-L38 PolarHBondContact OD1-N 3.2Å; L38-Q40 VanDerWaalsContact C-N 3.27Å; L38-Q40 HydrophobicContact CB-CB 4.33Å; L38-Q40 HydrophobicContact CB-CG 3.84Å; L38-Q503 HydrophobicContact CD2-CG 3.78Å; L38-Q504 PolarHBondContact O-NE2 3.08Å; L38-E507 WeakPolarHBondContact CD2-OE1 3.39Å
39G90.1Very high86.7Confident0 Ų061 Ų610%031%0.305CS..THydrogen-bonded Turntrans70.127.1-174.500000112.2D35 T58 F59 V62D35-G39 PolarHBondContact O-N 3.39Å; G39-T58 WeakPolarHBondContact O-CA 3.33Å; G39-F59 PolarHBondContact O-N 3.19Å; G39-V62 VanDerWaalsContact C-CG1 3.42Å; G39-V62 VanDerWaalsContact O-CG1 3.27Å; G39-V62 WeakPolarHBondContact O-CG1 3.46Å
40Q92.7Very high85.3Confident54 Ų5461.3 Ų61.325%0.25232%0.321SS..EExtended strand (participates in β ladder)trans-111.2143.1-170.3-66.3-176.819.300113.1D35 L38 T56 F57 T58D35-Q40 HydrophobicContact CB-CB 4.35Å; D35-Q40 PolarHBondContact N-O 3.2Å; D35-Q40 PolarHBondContact O-N 3.41Å; L38-Q40 VanDerWaalsContact C-N 3.27Å; L38-Q40 HydrophobicContact CB-CB 4.33Å; L38-Q40 HydrophobicContact CB-CG 3.84Å; Q40-T56 HydrophobicContact CB-CG2 4.35Å; Q40-F57 CarbonylContact C-O 3.6Å; Q40-F57 VanDerWaalsContact CA-O 3.29Å; Q40-F57 WeakPolarHBondContact CA-O 3.47Å; Q40-T58 HydrophobicContact CG-CG2 4.09Å
41V95Very high83.6Confident1 Ų164.3 Ų64.31%0.00634%0.336CS..EExtended strand (participates in β ladder)trans-122.5124.4170-175.30000108.7V14 V32 V43 T56 F57 F59 V62 I317 L331V14-V41 HydrophobicContact CB-CG2 4.01Å; V14-V41 HydrophobicContact CG1-CG2 3.95Å; V14-V41 HydrophobicContact CG2-CG2 4.3Å; V32-V41 HydrophobicContact CG1-CG1 3.69Å; V41-V43 HydrophobicContact CG1-CG2 4.34Å; V41-T56 CarbonylContact O-C 3.58Å; V41-T56 WeakPolarHBondContact O-CA 3.41Å; V41-F57 PolarHBondContact N-O 2.95Å; V41-F57 PolarHBondContact O-N 2.81Å; V41-F59 HydrophobicContact CB-CE2 4.47Å; V41-F59 HydrophobicContact CG2-CD2 4.32Å; V41-F59 HydrophobicContact CG2-CE2 4.32Å; V41-V62 HydrophobicContact CG2-CB 4.07Å; V41-V62 HydrophobicContact CG2-CG1 3.68Å; V41-I317 HydrophobicContact CG1-CD1 4.01Å; V41-L331 HydrophobicContact CB-CD2 4.31Å; V41-L331 HydrophobicContact CG1-CD1 4.02Å; V41-L331 HydrophobicContact CG1-CD2 4.23Å
42S93.1Very high82.4Confident27 Ų2767 Ų6719%0.18935%0.348CS..EExtended strand (participates in β ladder)trans-114.6129.4177.8-163.80000110.3N33 P54 K55 T56N33-S42 PolarHBondContact N-O 3.31Å; N33-S42 PolarHBondContact O-N 3.26Å; S42-P54 VanDerWaalsContact OG-CB 3.29Å; S42-P54 WeakPolarHBondContact OG-CB 3.5Å; S42-K55 CarbonylContact C-O 3.59Å; S42-K55 WeakPolarHBondContact CA-O 3.4Å; S42-T56 WeakPolarHBondContact CB-OG1 3.28Å; S42-T56 PolarHBondContact OG-OG1 2.63Å
43V93Very high81.4Confident1 Ų172.3 Ų72.31%0.00638%0.376CS..EExtended strand (participates in β ladder)trans-119.4119.9-177.4-175.40000109.8V32 V41 P54 K55 V324 T327 L328 L331V32-V43 HydrophobicContact CG2-CG2 4.37Å; V41-V43 HydrophobicContact CG1-CG2 4.34Å; V43-P54 WeakPolarHBondContact O-CA 3.32Å; V43-K55 PolarHBondContact N-O 3.18Å; V43-K55 PolarHBondContact O-N 3.35Å; V43-V324 HydrophobicContact CG1-CG2 3.71Å; V43-T327 HydrophobicContact CG2-CG2 4.23Å; V43-L328 HydrophobicContact CB-CD2 3.92Å; V43-L328 HydrophobicContact CG1-CD2 3.94Å; V43-L328 HydrophobicContact CG1-CG 4.19Å; V43-L328 HydrophobicContact CG2-CD2 4.37Å; V43-L331 HydrophobicContact CG2-CD1 3.41Å; V43-L331 VanDerWaalsContact CG2-CD1 3.41Å
44K88.4Confident80.9Confident123 Ų12370.4 Ų70.454%0.53537%0.369SS..  trans-85.6128.9173-172.9-175.2177.7-166.30109.4V31 P46V31-K44 WeakPolarHBondContact CB-O 3.31Å; V31-K44 PolarHBondContact O-N 2.65Å; K44-P46 VanDerWaalsContact O-CD 3.28Å; K44-P46 WeakPolarHBondContact O-CD 3.31Å
45N80.8Confident80.5Confident46 Ų4671.8 Ų71.825%0.24637%0.374CS..  trans-80113.8170.9-174.74.6000109.9R47 G48 E52N45-R47 PolarHBondContact O-N 3.06Å; N45-R47 PolarHBondContact OD1-N 3.03Å; N45-G48 VanDerWaalsContact CG-N 3.34Å; N45-G48 PolarHBondContact ND2-N 2.94Å; N45-G48 PolarHBondContact O-N 3.48Å; N45-G48 PolarHBondContact OD1-N 3.16Å; N45-E52 WeakPolarHBondContact CB-OE2 3.4Å; N45-E52 PolarHBondContact ND2-OE2 3Å
46P75.7Confident80.3Confident55 Ų5572.1 Ų72.136%0.35738%0.378SS..THydrogen-bonded Turntrans-73.5-15.817832.7-36.7000112.9V31 K44 V324V31-P46 HydrophobicContact CG1-CB 4.33Å; V31-P46 HydrophobicContact CG1-CG 4.22Å; K44-P46 VanDerWaalsContact O-CD 3.28Å; K44-P46 WeakPolarHBondContact O-CD 3.31Å; P46-V324 HydrophobicContact CG-CG1 4.22Å
47R70.7Confident80.3Confident182 Ų18270.6 Ų70.669%0.68737%0.368SS*.THydrogen-bonded Turntrans-99.10.4173.7-59.5-173.4-170149.78.8113N45 E325N45-R47 PolarHBondContact O-N 3.06Å; N45-R47 PolarHBondContact OD1-N 3.03Å; R47-E325 IonicContact CZ-OE1 3.24Å; R47-E325 IonicContact NH1-OE1 3.26Å; R47-E325 PolarHBondContact NH1-OE1 2.84Å; R47-E325 IonicContact NH2-OE1 3.56Å
48G63.3Low80.6Confident23 Ų2365.3 Ų65.324%0.23735%0.349CS..SBendtrans-67.5157.5177.800000111.7N45 E52N45-G48 VanDerWaalsContact CG-N 3.34Å; N45-G48 PolarHBondContact ND2-N 2.94Å; N45-G48 PolarHBondContact O-N 3.48Å; N45-G48 PolarHBondContact OD1-N 3.16Å; G48-E52 WeakPolarHBondContact CA-OE2 3.2Å
49T63.5Low81.1Confident106 Ų10664.4 Ų64.465%0.6534%0.344SS*.  trans-62157.3165.763.50000109.7H51 E52T49-H51 PolarHBondContact O-N 3.03Å; T49-E52 PolarHBondContact O-N 3.45Å
50S60.6Low81.2Confident128 Ų12868.2 Ų68.290%0.89537%0.365SS*.THydrogen-bonded Turntrans-57.6-7.5179.5-43.20000115.1
51H57Low81.3Confident172 Ų17265.8 Ų65.880%0.79635%0.354SS*.THydrogen-bonded Turntrans-109-2.6177.6-66.3-71.4000114.2T49 L53T49-H51 PolarHBondContact O-N 3.03Å; H51-L53 PolarHBondContact O-N 3.37Å
52E67.9Low81.3Confident66 Ų6665.8 Ų65.831%0.30835%0.354SS..  trans-70.1115.9175.2-164.9-174.1167.800109.9N45 G48 T49 K55N45-E52 WeakPolarHBondContact CB-OE2 3.4Å; N45-E52 PolarHBondContact ND2-OE2 3Å; G48-E52 WeakPolarHBondContact CA-OE2 3.2Å; T49-E52 PolarHBondContact O-N 3.45Å; E52-K55 WeakPolarHBondContact OE1-CE 3.43Å; E52-K55 IonicContact OE1-NZ 3.73Å; E52-K55 PolarHBondContact OE1-NZ 3.06Å
53L75.2Confident81.5Confident114 Ų11464.9 Ų64.960%0.59735%0.346SS*.PPolyproline II helixtrans-71.3145.6178.8-70.8171.2000111.2H51 K55H51-L53 PolarHBondContact O-N 3.37Å; L53-K55 PolarHBondContact O-N 3.41Å
54P83Confident81.6Confident64 Ų6466 Ų6642%0.41635%0.352SS..PPolyproline II helixtrans-57.1127.8174.6-25.435.3000112.7S42 V43 T56S42-P54 VanDerWaalsContact OG-CB 3.29Å; S42-P54 WeakPolarHBondContact OG-CB 3.5Å; V43-P54 WeakPolarHBondContact O-CA 3.32Å; P54-T56 PolarHBondContact O-N 3.16Å; P54-T56 PolarHBondContact O-OG1 3.49Å
55K86.8Confident81.9Confident43 Ų4363.7 Ų63.719%0.18734%0.34CS..EExtended strand (participates in β ladder)trans-75116.3178.8-75.9161.9172.7156.40108.6S42 V43 E52 L53 F57 L328 D550S42-K55 CarbonylContact C-O 3.59Å; S42-K55 WeakPolarHBondContact CA-O 3.4Å; V43-K55 PolarHBondContact N-O 3.18Å; V43-K55 PolarHBondContact O-N 3.35Å; E52-K55 WeakPolarHBondContact OE1-CE 3.43Å; E52-K55 IonicContact OE1-NZ 3.73Å; E52-K55 PolarHBondContact OE1-NZ 3.06Å; L53-K55 PolarHBondContact O-N 3.41Å; K55-F57 HydrophobicContact CB-CE2 4.01Å; K55-F57 HydrophobicContact CB-CZ 4.35Å; K55-L328 HydrophobicContact CB-CD2 4.11Å; K55-L328 HydrophobicContact CD-CD1 4.41Å; K55-L328 HydrophobicContact CD-CD2 4.09Å; K55-D550 WeakPolarHBondContact CE-OD2 2.81Å; K55-D550 IonicContact NZ-OD1 3.77Å; K55-D550 IonicContact NZ-OD2 3.2Å; K55-D550 PolarHBondContact NZ-OD2 3.24Å
56T88.4Confident82.5Confident71 Ų7167 Ų6744%0.43636%0.358SS..EExtended strand (participates in β ladder)trans-118.3132.1-170.7-53.80000110.7Q40 V41 S42 P54Q40-T56 HydrophobicContact CB-CG2 4.35Å; V41-T56 CarbonylContact O-C 3.58Å; V41-T56 WeakPolarHBondContact O-CA 3.41Å; S42-T56 WeakPolarHBondContact CB-OG1 3.28Å; S42-T56 PolarHBondContact OG-OG1 2.63Å; P54-T56 PolarHBondContact O-N 3.16Å; P54-T56 PolarHBondContact O-OG1 3.49Å
57F91.9Very high83.3Confident17 Ų1765.3 Ų65.38%0.07535%0.347CS..EExtended strand (participates in β ladder)trans-129.7140.6-172.7-57.5-91.3000110.4Q40 V41 K55 F59 L328 L331 R332 N335Q40-F57 CarbonylContact C-O 3.6Å; Q40-F57 VanDerWaalsContact CA-O 3.29Å; Q40-F57 WeakPolarHBondContact CA-O 3.47Å; V41-F57 PolarHBondContact N-O 2.95Å; V41-F57 PolarHBondContact O-N 2.81Å; K55-F57 HydrophobicContact CB-CE2 4.01Å; K55-F57 HydrophobicContact CB-CZ 4.35Å; F57-F59 HydrophobicContact CB-CD2 4.35Å; F57-F59 HydrophobicContact CB-CE2 3.39Å; F57-F59 HydrophobicContact CB-CZ 3.7Å; F57-F59 HydrophobicContact CG-CE2 4.44Å; F57-F59 HydrophobicContact CG-CZ 4.42Å; F57-L328 HydrophobicContact CE2-CD2 4.1Å; F57-L328 HydrophobicContact CZ-CD2 4.37Å; F57-L331 HydrophobicContact CD2-CB 4.01Å; F57-L331 HydrophobicContact CD2-CD1 3.97Å; F57-L331 HydrophobicContact CD2-CG 4.48Å; F57-L331 HydrophobicContact CE1-CB 4.5Å; F57-L331 HydrophobicContact CE2-CB 3.96Å; F57-L331 HydrophobicContact CE2-CD1 4.06Å; F57-L331 HydrophobicContact CG-CB 4.3Å; F57-L331 HydrophobicContact CZ-CB 4.21Å; F57-R332 HydrophobicContact CE1-CG 4.37Å; F57-R332 HydrophobicContact CZ-CG 4.4Å; F57-N335 HydrophobicContact CD1-CB 4.19Å
58T91.6Very high84.4Confident53 Ų5362.5 Ų62.533%0.32534%0.34SS..EExtended strand (participates in β ladder)trans-114133.9179.8-43.80000111.5G39 Q40 K338G39-T58 WeakPolarHBondContact O-CA 3.33Å; Q40-T58 HydrophobicContact CG-CG2 4.09Å; T58-K338 PolarHBondContact O-NZ 2.92Å
59F94.6Very high85.8Confident7 Ų761.7 Ų61.73%0.03133%0.33CS..  trans-131.7171.7-174.5-60.7-80.5000111.7V12 V14 G39 V41 F57 A61 V62 L331 A334 N335V12-F59 HydrophobicContact CB-CD1 4.3Å; V12-F59 HydrophobicContact CG1-CD1 3.78Å; V12-F59 HydrophobicContact CG1-CE1 4.15Å; V14-F59 HydrophobicContact CB-CD2 4.42Å; V14-F59 HydrophobicContact CG2-CD1 4Å; V14-F59 HydrophobicContact CG2-CD2 3.4Å; V14-F59 VanDerWaalsContact CG2-CD2 3.4Å; V14-F59 HydrophobicContact CG2-CE1 4.01Å; V14-F59 HydrophobicContact CG2-CE2 3.4Å; V14-F59 VanDerWaalsContact CG2-CE2 3.4Å; V14-F59 HydrophobicContact CG2-CG 3.7Å; V14-F59 HydrophobicContact CG2-CZ 3.72Å; G39-F59 PolarHBondContact O-N 3.19Å; V41-F59 HydrophobicContact CB-CE2 4.47Å; V41-F59 HydrophobicContact CG2-CD2 4.32Å; V41-F59 HydrophobicContact CG2-CE2 4.32Å; F57-F59 HydrophobicContact CB-CD2 4.35Å; F57-F59 HydrophobicContact CB-CE2 3.39Å; F57-F59 HydrophobicContact CB-CZ 3.7Å; F57-F59 HydrophobicContact CG-CE2 4.44Å; F57-F59 HydrophobicContact CG-CZ 4.42Å; F59-A61 VanDerWaalsContact C-N 3.3Å; F59-A61 PolarHBondContact O-N 3.4Å; F59-V62 HydrophobicContact CB-CG1 4.07Å; F59-V62 HydrophobicContact CD2-CG1 4.03Å; F59-L331 HydrophobicContact CE2-CD2 3.74Å; F59-L331 HydrophobicContact CZ-CD2 3.76Å; F59-A334 HydrophobicContact CE1-CB 3.66Å; F59-A334 HydrophobicContact CZ-CB 4.2Å; F59-N335 HydrophobicContact CE1-CB 4.3Å; F59-N335 HydrophobicContact CZ-CB 4.49Å
60D92.8Very high87Confident80 Ų8059 Ų5943%0.42831%0.313SS..SBendtrans-62.4-38179-60.5-88.4000112R11 V12R11-D60 WeakPolarHBondContact CA-OD2 3.39Å; V12-D60 PolarHBondContact N-OD2 3.14Å; V12-D60 PolarHBondContact O-N 3.18Å
61A93.7Very high88.3Confident3 Ų357.1 Ų57.13%0.02529%0.291CS..EExtended strand (participates in β ladder)trans-153.4155.1168.500000110.9V13 V14 F59 Y63V13-A61 VanDerWaalsContact CA-O 3.24Å; V13-A61 WeakPolarHBondContact CA-O 3.48Å; V13-A61 HydrophobicContact CB-CB 4.46Å; V13-A61 WeakPolarHBondContact CB-O 3.38Å; V13-A61 HydrophobicContact CG1-CB 3.82Å; V14-A61 PolarHBondContact N-O 3.16Å; V14-A61 VanDerWaalsContact N-O 3.16Å; F59-A61 VanDerWaalsContact C-N 3.3Å; F59-A61 PolarHBondContact O-N 3.4Å; A61-Y63 HydrophobicContact CB-CE2 3.83Å
62V95.8Very high90Very high1 Ų149 Ų491%0.00625%0.253CS..EExtended strand (participates in β ladder)trans-134.5142.4175.6-54.80000110.2V14 V34 D35 G39 V41 F59V14-V62 HydrophobicContact CB-CG1 4.31Å; V14-V62 CarbonylContact O-C 3.6Å; V14-V62 WeakPolarHBondContact O-CA 3.3Å; V34-V62 HydrophobicContact CG1-CB 3.93Å; V34-V62 HydrophobicContact CG1-CG2 3.53Å; D35-V62 WeakPolarHBondContact O-CG2 3.45Å; G39-V62 VanDerWaalsContact C-CG1 3.42Å; G39-V62 VanDerWaalsContact O-CG1 3.27Å; G39-V62 WeakPolarHBondContact O-CG1 3.46Å; V41-V62 HydrophobicContact CG2-CB 4.07Å; V41-V62 HydrophobicContact CG2-CG1 3.68Å; F59-V62 HydrophobicContact CB-CG1 4.07Å; F59-V62 HydrophobicContact CD2-CG1 4.03Å
63Y96.4Very high91.2Very high7 Ų746.2 Ų46.23%0.02724%0.24CC..EExtended strand (participates in β ladder)trans-125.8124.7-172.7-63.5-83.6000109.7V13 V14 C16 A61 L72 E75 T76V13-Y63 HydrophobicContact CB-CD2 4.4Å; V13-Y63 HydrophobicContact CB-CE2 4.01Å; V13-Y63 HydrophobicContact CG1-CE2 4.33Å; V13-Y63 HydrophobicContact CG2-CE2 4.32Å; V14-Y63 PolarHBondContact O-N 3.47Å; C16-Y63 PolarHBondContact N-O 3.17Å; A61-Y63 HydrophobicContact CB-CE2 3.83Å; Y63-L72 HydrophobicContact CD1-CD1 4.22Å; Y63-L72 HydrophobicContact CD2-CD1 3.54Å; Y63-L72 HydrophobicContact CE1-CB 4.25Å; Y63-L72 HydrophobicContact CE1-CD1 3.95Å; Y63-L72 HydrophobicContact CE2-CD1 3.23Å; Y63-L72 HydrophobicContact CG-CD1 4.02Å; Y63-L72 VanDerWaalsContact CZ-CD1 3.44Å; Y63-E75 PolarHBondContact OH-OE1 3.47Å; Y63-T76 PolarHBondContact OH-OG1 3.34Å
64D95Very high91.9Very high25 Ų2541.7 Ų41.713%0.13422%0.216CC..  trans-84.6-176.9-179.682.1-24.6000112.1C16 V34 V36 N66 S67C16-D64 CarbonylContact O-C 3.53Å; C16-D64 VanDerWaalsContact O-C 3.24Å; V34-D64 HydrophobicContact CB-CB 4.25Å; V34-D64 HydrophobicContact CG1-CB 4.21Å; V36-D64 HydrophobicContact CG2-CB 4.1Å; D64-N66 PolarHBondContact O-N 2.85Å; D64-N66 WeakPolarHBondContact OD1-CA 3.4Å; D64-N66 WeakPolarHBondContact OD1-CB 3.41Å; D64-N66 PolarHBondContact OD1-N 2.65Å; D64-N66 PolarHBondContact OD2-ND2 2.94Å; D64-S67 PolarHBondContact N-OG 2.97Å; D64-S67 WeakPolarHBondContact O-CB 3.35Å; D64-S67 PolarHBondContact O-N 3.33Å; D64-S67 PolarHBondContact O-OG 3.28Å; D64-S67 PolarHBondContact OD1-N 3.09Å; D64-S67 PolarHBondContact OD1-OG 2.66Å
65W94.3Very high92.2Very high75 Ų7540.3 Ų40.328%0.28420%0.204SC..THydrogen-bonded Turntrans-66.6-11.1177.549.179.9000114.3C16 P18 K30 V34C16-W65 WeakPolarHBondContact O-CA 3.41Å; C16-W65 PolarHBondContact O-N 2.73Å; P18-W65 HydrophobicContact CB-CB 4.31Å; P18-W65 HydrophobicContact CG-CB 4.06Å; P18-W65 WeakPolarHBondContact CG-O 3.26Å; K30-W65 VanDerWaalsContact NZ-CE2 3.3Å; K30-W65 VanDerWaalsContact NZ-CE3 3.32Å; V34-W65 HydrophobicContact CB-CZ3 4.4Å; V34-W65 HydrophobicContact CG2-CZ3 4.25Å
66N94.4Very high92.4Very high116 Ų11638.8 Ų38.862%0.6220%0.198SC*.THydrogen-bonded Turntrans-95.7-15.1176.5-59.4-55.4000113D64 K68D64-N66 PolarHBondContact O-N 2.85Å; D64-N66 WeakPolarHBondContact OD1-CA 3.4Å; D64-N66 WeakPolarHBondContact OD1-CB 3.41Å; D64-N66 PolarHBondContact OD1-N 2.65Å; D64-N66 PolarHBondContact OD2-ND2 2.94Å; N66-K68 PolarHBondContact O-N 2.95Å
67S93.3Very high92.8Very high19 Ų1935.5 Ų35.513%0.13318%0.178CC..  trans-67.3124.9-169.3-63.30000113.6D64D64-S67 PolarHBondContact N-OG 2.97Å; D64-S67 WeakPolarHBondContact O-CB 3.35Å; D64-S67 PolarHBondContact O-N 3.33Å; D64-S67 PolarHBondContact O-OG 3.28Å; D64-S67 PolarHBondContact OD1-N 3.09Å; D64-S67 PolarHBondContact OD1-OG 2.66Å
68K92.6Very high92.9Very high122 Ų12235.7 Ų35.753%0.5318%0.178SC..  trans-81159.9-174.5-59.1-176.6179.5-174.40112.7N66 E71 L72N66-K68 PolarHBondContact O-N 2.95Å; K68-E71 HydrophobicContact CB-CB 4.44Å; K68-E71 HydrophobicContact CB-CG 4.1Å; K68-E71 WeakPolarHBondContact CB-OE2 3.45Å; K68-E71 PolarHBondContact N-OE2 3.31Å; K68-L72 PolarHBondContact O-N 3.13Å
69Q92.9Very high92.9Very high7 Ų735.3 Ų35.33%0.03318%0.177CC..Hα-helixtrans-62.8-42.9176.7-59.5-78.458.400112.4L72 Y73 Y104 K115 R116Q69-L72 PolarHBondContact O-N 3.18Å; Q69-Y73 WeakPolarHBondContact O-CB 3.42Å; Q69-Y73 PolarHBondContact O-N 2.81Å; Q69-Y104 PolarHBondContact NE2-O 2.74Å; Q69-K115 PolarHBondContact NE2-O 2.99Å; Q69-R116 WeakPolarHBondContact CB-O 3.3Å; Q69-R116 WeakPolarHBondContact CG-O 3.37Å
70V89.6Confident93Very high48 Ų4835.2 Ų35.229%0.29118%0.176SC..Hα-helixtrans-66.1-40.8-177.5-178.90000111.1Y73 D74V70-Y73 PolarHBondContact O-N 3.32Å; V70-D74 WeakPolarHBondContact O-CB 3.43Å; V70-D74 PolarHBondContact O-N 2.96Å
71E88.3Confident93.1Very high90 Ų9031.4 Ų31.442%0.42116%0.156SC..Hα-helixtrans-62.1-47.6176.5-66.8163.3173.700111.2K68 Y73 E75K68-E71 HydrophobicContact CB-CB 4.44Å; K68-E71 HydrophobicContact CB-CG 4.1Å; K68-E71 WeakPolarHBondContact CB-OE2 3.45Å; K68-E71 PolarHBondContact N-OE2 3.31Å; E71-Y73 VanDerWaalsContact C-N 3.3Å; E71-Y73 PolarHBondContact O-N 2.93Å; E71-E75 VanDerWaalsContact O-CB 3.25Å; E71-E75 WeakPolarHBondContact O-CB 3.42Å; E71-E75 PolarHBondContact O-N 3.06Å
72L91.5Very high93.1Very high1 Ų133.3 Ų33.31%0.00517%0.166CC..Hα-helixtrans-59.7-39.1174.7175.864.8000112.1Y63 K68 Q69 T76 F77 T105Y63-L72 HydrophobicContact CD1-CD1 4.22Å; Y63-L72 HydrophobicContact CD2-CD1 3.54Å; Y63-L72 HydrophobicContact CE1-CB 4.25Å; Y63-L72 HydrophobicContact CE1-CD1 3.95Å; Y63-L72 HydrophobicContact CE2-CD1 3.23Å; Y63-L72 HydrophobicContact CG-CD1 4.02Å; Y63-L72 VanDerWaalsContact CZ-CD1 3.44Å; K68-L72 PolarHBondContact O-N 3.13Å; Q69-L72 PolarHBondContact O-N 3.18Å; L72-T76 WeakPolarHBondContact O-CB 3.35Å; L72-T76 PolarHBondContact O-N 3.24Å; L72-T76 VanDerWaalsContact O-N 3.1Å; L72-F77 HydrophobicContact CD1-CE2 4.19Å; L72-F77 HydrophobicContact CD1-CZ 4.01Å; L72-F77 HydrophobicContact CD2-CE2 3.89Å; L72-F77 HydrophobicContact CD2-CZ 4.13Å; L72-F77 HydrophobicContact CG-CD2 4.39Å; L72-F77 HydrophobicContact CG-CE2 3.56Å; L72-F77 HydrophobicContact CG-CZ 3.87Å; L72-T105 HydrophobicContact CD2-CG2 3.76Å
73Y93.7Very high93.1Very high7 Ų734 Ų343%0.02717%0.171CC..Iπ-helixtrans-69.2-54.6177.9-173.8-87000112.7Q69 V70 E71 E75 F77 R78 V118 N121 S122 H125Q69-Y73 WeakPolarHBondContact O-CB 3.42Å; Q69-Y73 PolarHBondContact O-N 2.81Å; V70-Y73 PolarHBondContact O-N 3.32Å; E71-Y73 VanDerWaalsContact C-N 3.3Å; E71-Y73 PolarHBondContact O-N 2.93Å; Y73-E75 VanDerWaalsContact C-N 3.27Å; Y73-E75 PolarHBondContact O-N 3.29Å; Y73-F77 HydrophobicContact CD2-CB 3.89Å; Y73-F77 HydrophobicContact CD2-CD2 4.01Å; Y73-F77 HydrophobicContact CD2-CG 4.48Å; Y73-F77 HydrophobicContact CE2-CB 4.06Å; Y73-F77 HydrophobicContact CG-CB 4.45Å; Y73-F77 PolarHBondContact O-N 3.31Å; Y73-R78 HydrophobicContact CD1-CB 4.33Å; Y73-R78 HydrophobicContact CE1-CB 4Å; Y73-R78 WeakPolarHBondContact O-CB 3.35Å; Y73-R78 PolarHBondContact O-N 3.46Å; Y73-V118 HydrophobicContact CD2-CB 4.39Å; Y73-V118 HydrophobicContact CD2-CG2 3.98Å; Y73-V118 HydrophobicContact CE2-CG2 4.01Å; Y73-N121 HydrophobicContact CD1-CB 4.28Å; Y73-N121 HydrophobicContact CD2-CB 3.46Å; Y73-N121 VanDerWaalsContact CD2-CB 3.46Å; Y73-N121 HydrophobicContact CE1-CB 4.42Å; Y73-N121 HydrophobicContact CE2-CB 3.63Å; Y73-N121 HydrophobicContact CG-CB 3.83Å; Y73-S122 WeakPolarHBondContact OH-CA 3.34Å; Y73-H125 HydrophobicContact CE1-CB 4.34Å; Y73-H125 VanDerWaalsContact OH-CB 3.28Å; Y73-H125 WeakPolarHBondContact OH-CB 3.46Å; Y73-H125 PolarHBondContact OH-ND1 2.82Å
74D90.1Very high93.1Very high20 Ų2033.7 Ų33.711%0.10717%0.17CC..Iπ-helixtrans-63.2-33.3-176.6-77.8-25.1000111.6V70 R78 R489V70-D74 WeakPolarHBondContact O-CB 3.43Å; V70-D74 PolarHBondContact O-N 2.96Å; D74-R78 IonicContact OD1-CZ 2.78Å; D74-R78 VanDerWaalsContact OD1-CZ 3.24Å; D74-R78 IonicContact OD1-NE 2.81Å; D74-R78 PolarHBondContact OD1-NE 3.03Å; D74-R78 IonicContact OD1-NH2 2.65Å; D74-R78 PolarHBondContact OD1-NH2 2.59Å; D74-R489 IonicContact OD2-CZ 2.73Å; D74-R489 IonicContact OD2-NH1 2.59Å; D74-R489 PolarHBondContact OD2-NH1 3.19Å
75E88.9Confident93Very high34 Ų3432.6 Ų32.616%0.15916%0.164CC..Iπ-helixtrans-82.8-48179.7-171.4-176.9135.900113.9Y63 E71 Y73 R500Y63-E75 PolarHBondContact OH-OE1 3.47Å; E71-E75 VanDerWaalsContact O-CB 3.25Å; E71-E75 WeakPolarHBondContact O-CB 3.42Å; E71-E75 PolarHBondContact O-N 3.06Å; Y73-E75 VanDerWaalsContact C-N 3.27Å; Y73-E75 PolarHBondContact O-N 3.29Å; E75-R500 IonicContact OE1-CZ 3.83Å; E75-R500 IonicContact OE1-NH1 3.68Å; E75-R500 PolarHBondContact OE1-NH1 3.34Å; E75-R500 IonicContact OE1-NH2 3.82Å; E75-R500 PolarHBondContact OE1-NH2 2.82Å; E75-R500 IonicContact OE2-CZ 2.6Å; E75-R500 IonicContact OE2-NH1 2.66Å; E75-R500 IonicContact OE2-NH2 3.72Å; E75-R500 PolarHBondContact OE2-NH2 2.59Å
76T91.6Very high92.9Very high11 Ų1133.4 Ų33.47%0.06717%0.171CC..Iπ-helixtrans-102.9-43.5-169.8-61.90000113.8V13 Y63 L72 V312V13-T76 HydrophobicContact CG1-CG2 3.71Å; V13-T76 HydrophobicContact CG2-CG2 4.11Å; Y63-T76 PolarHBondContact OH-OG1 3.34Å; L72-T76 WeakPolarHBondContact O-CB 3.35Å; L72-T76 PolarHBondContact O-N 3.24Å; L72-T76 VanDerWaalsContact O-N 3.1Å; T76-V312 HydrophobicContact CG2-CG1 3.65Å
77F95.4Very high92.8Very high2 Ų228 Ų281%0.00914%0.142CC..Iπ-helixtrans-92.6-34.5-167.9-54-40.5000113.3L72 Y73 L80 V81 I92 T105 V118 V312 V314L72-F77 HydrophobicContact CD1-CE2 4.19Å; L72-F77 HydrophobicContact CD1-CZ 4.01Å; L72-F77 HydrophobicContact CD2-CE2 3.89Å; L72-F77 HydrophobicContact CD2-CZ 4.13Å; L72-F77 HydrophobicContact CG-CD2 4.39Å; L72-F77 HydrophobicContact CG-CE2 3.56Å; L72-F77 HydrophobicContact CG-CZ 3.87Å; Y73-F77 HydrophobicContact CD2-CB 3.89Å; Y73-F77 HydrophobicContact CD2-CD2 4.01Å; Y73-F77 HydrophobicContact CD2-CG 4.48Å; Y73-F77 HydrophobicContact CE2-CB 4.06Å; Y73-F77 HydrophobicContact CG-CB 4.45Å; Y73-F77 PolarHBondContact O-N 3.31Å; F77-L80 WeakPolarHBondContact O-CB 3.27Å; F77-L80 PolarHBondContact O-N 2.98Å; F77-V81 PolarHBondContact O-N 3.49Å; F77-I92 HydrophobicContact CB-CD1 3.96Å; F77-I92 HydrophobicContact CD1-CD1 3.81Å; F77-I92 HydrophobicContact CD1-CG1 4.45Å; F77-I92 HydrophobicContact CD1-CG2 4.07Å; F77-I92 HydrophobicContact CE1-CG2 3.84Å; F77-I92 HydrophobicContact CG-CD1 3.99Å; F77-I92 HydrophobicContact CZ-CG2 4.45Å; F77-T105 HydrophobicContact CZ-CG2 4.4Å; F77-V118 HydrophobicContact CB-CG2 3.81Å; F77-V118 HydrophobicContact CD1-CG2 4.34Å; F77-V118 HydrophobicContact CD2-CB 3.54Å; F77-V118 HydrophobicContact CD2-CG1 4.48Å; F77-V118 HydrophobicContact CD2-CG2 3.32Å; F77-V118 HydrophobicContact CE2-CB 3.69Å; F77-V118 HydrophobicContact CE2-CG1 4.27Å; F77-V118 HydrophobicContact CE2-CG2 3.93Å; F77-V118 HydrophobicContact CG-CB 4.28Å; F77-V118 HydrophobicContact CG-CG2 3.58Å; F77-V312 HydrophobicContact CD1-CG1 4.16Å; F77-V312 HydrophobicContact CE1-CG1 3.88Å; F77-V314 HydrophobicContact CE1-CG2 3.57Å; F77-V314 HydrophobicContact CZ-CG2 3.55Å
78R93.6Very high92.8Very high22 Ų2229 Ų298%0.08314%0.144CC..Hα-helixtrans-51.9-51.4179.6170.5177.6-63.6-85.314.4112.9Y73 D74 L80 V81 D82 H125 E486Y73-R78 HydrophobicContact CD1-CB 4.33Å; Y73-R78 HydrophobicContact CE1-CB 4Å; Y73-R78 WeakPolarHBondContact O-CB 3.35Å; Y73-R78 PolarHBondContact O-N 3.46Å; D74-R78 IonicContact OD1-CZ 2.78Å; D74-R78 VanDerWaalsContact OD1-CZ 3.24Å; D74-R78 IonicContact OD1-NE 2.81Å; D74-R78 PolarHBondContact OD1-NE 3.03Å; D74-R78 IonicContact OD1-NH2 2.65Å; D74-R78 PolarHBondContact OD1-NH2 2.59Å; R78-L80 PolarHBondContact O-N 3.38Å; R78-L80 VanDerWaalsContact O-N 3.1Å; R78-V81 PolarHBondContact O-N 3.4Å; R78-D82 VanDerWaalsContact C-OD2 3.31Å; R78-D82 WeakPolarHBondContact CG-OD2 3.46Å; R78-D82 VanDerWaalsContact O-CG 3.26Å; R78-D82 PolarHBondContact O-N 2.92Å; R78-H125 PolarHBondContact NH1-CD2 3.07Å; R78-H125 VanDerWaalsContact NH1-CD2 3.29Å; R78-H125 PolarHBondContact NH1-NE2 2.91Å; R78-H125 VanDerWaalsContact NH1-NE2 3.14Å; R78-E486 IonicContact CZ-OE1 3.6Å; R78-E486 IonicContact NH1-OE1 3.82Å; R78-E486 PolarHBondContact NH1-OE1 2.98Å; R78-E486 IonicContact NH2-OE1 3.88Å; R78-E486 PolarHBondContact NH2-OE1 3.3Å
79P93.1Very high92.9Very high45 Ų4524.4 Ų24.429%0.29213%0.125SC..Hα-helixtrans-62-23178.2-23.434.7000114.9D82 S83P79-D82 WeakPolarHBondContact CA-OD2 3.36Å; P79-S83 PolarHBondContact O-N 3.23Å; P79-S83 PolarHBondContact O-OG 3.09Å
80L95.6Very high93.1Very high4 Ų424.1 Ų24.12%0.02112%0.124CC..Hα-helixtrans-76.5-46.3173.3-170.179.7000110.7F77 R78 D82 S83 V84 I92 L241 K310 V312F77-L80 WeakPolarHBondContact O-CB 3.27Å; F77-L80 PolarHBondContact O-N 2.98Å; R78-L80 PolarHBondContact O-N 3.38Å; R78-L80 VanDerWaalsContact O-N 3.1Å; L80-D82 VanDerWaalsContact C-N 3.33Å; L80-D82 PolarHBondContact O-N 3.39Å; L80-S83 WeakPolarHBondContact O-CA 3.44Å; L80-S83 VanDerWaalsContact O-CB 3.31Å; L80-S83 WeakPolarHBondContact O-CB 3.28Å; L80-S83 PolarHBondContact O-N 2.98Å; L80-V84 PolarHBondContact O-N 3.46Å; L80-I92 HydrophobicContact CD2-CD1 3.82Å; L80-I92 HydrophobicContact CD2-CG1 3.26Å; L80-L241 HydrophobicContact CD2-CD1 4.33Å; L80-K310 HydrophobicContact CD1-CB 3.33Å; L80-V312 HydrophobicContact CB-CG2 4.49Å; L80-V312 HydrophobicContact CD1-CG2 4.35Å; L80-V312 HydrophobicContact CD2-CG2 4.07Å
81V96.4Very high93.5Very high0 Ų021.8 Ų21.80%011%0.11CC..Hα-helixtrans-63.4-40.4177.2179.80000110.8F77 R78 S83 V84 L85 H125 I126 L241F77-V81 PolarHBondContact O-N 3.49Å; R78-V81 PolarHBondContact O-N 3.4Å; V81-S83 VanDerWaalsContact C-N 3.27Å; V81-S83 PolarHBondContact O-N 3.46Å; V81-V84 PolarHBondContact O-N 3.16Å; V81-L85 HydrophobicContact CG1-CD1 4.24Å; V81-L85 PolarHBondContact O-N 2.95Å; V81-H125 WeakPolarHBondContact CG1-ND1 3.48Å; V81-I126 HydrophobicContact CG1-CD1 4.27Å; V81-I126 HydrophobicContact CG1-CG1 3.76Å; V81-L241 HydrophobicContact CG2-CD2 4.04Å
82D93.9Very high94Very high44 Ų4417.5 Ų17.524%0.2359%0.09CC..Hα-helixtrans-53.9-44.4169.7-67.2-41.8000111.2R78 P79 L80 V84 L85 Q86 H125R78-D82 VanDerWaalsContact C-OD2 3.31Å; R78-D82 WeakPolarHBondContact CG-OD2 3.46Å; R78-D82 VanDerWaalsContact O-CG 3.26Å; R78-D82 PolarHBondContact O-N 2.92Å; P79-D82 WeakPolarHBondContact CA-OD2 3.36Å; L80-D82 VanDerWaalsContact C-N 3.33Å; L80-D82 PolarHBondContact O-N 3.39Å; D82-V84 VanDerWaalsContact C-N 3.34Å; D82-V84 PolarHBondContact O-N 2.95Å; D82-L85 PolarHBondContact O-N 3.46Å; D82-Q86 WeakPolarHBondContact O-CG 3.35Å; D82-Q86 PolarHBondContact O-N 2.92Å; D82-H125 IonicContact OD1-CE1 2.74Å; D82-H125 PolarHBondContact OD1-CE1 2.98Å; D82-H125 IonicContact OD1-NE2 2.85Å; D82-H125 PolarHBondContact OD1-NE2 3.19Å
83S95.1Very high94.2Very high15 Ų1517.6 Ų17.611%0.1059%0.09CC..Hα-helixtrans-64.7-36.1176.8-59.30000112.5P79 L80 V81 Q86 G87 F88 K310P79-S83 PolarHBondContact O-N 3.23Å; P79-S83 PolarHBondContact O-OG 3.09Å; L80-S83 WeakPolarHBondContact O-CA 3.44Å; L80-S83 VanDerWaalsContact O-CB 3.31Å; L80-S83 WeakPolarHBondContact O-CB 3.28Å; L80-S83 PolarHBondContact O-N 2.98Å; V81-S83 VanDerWaalsContact C-N 3.27Å; V81-S83 PolarHBondContact O-N 3.46Å; S83-Q86 PolarHBondContact O-N 2.83Å; S83-G87 PolarHBondContact O-N 3.45Å; S83-F88 WeakPolarHBondContact O-CB 3.35Å; S83-F88 WeakPolarHBondContact O-CD2 3.32Å; S83-F88 PolarHBondContact O-N 2.95Å; S83-K310 PolarHBondContact OG-NZ 3.39Å
84V95.9Very high94.3Very high1 Ų117.2 Ų17.21%0.0069%0.089CC..Hα-helixtrans-69.8-38.5176.8-1770000111.6L80 V81 D82 Q86 G87 F88 I223 L241L80-V84 PolarHBondContact O-N 3.46Å; V81-V84 PolarHBondContact O-N 3.16Å; D82-V84 VanDerWaalsContact C-N 3.34Å; D82-V84 PolarHBondContact O-N 2.95Å; V84-Q86 PolarHBondContact O-N 3.35Å; V84-G87 PolarHBondContact O-N 2.97Å; V84-F88 WeakPolarHBondContact CA-O 3.47Å; V84-I223 HydrophobicContact CG1-CD1 4.11Å; V84-L241 HydrophobicContact CB-CB 4.49Å; V84-L241 HydrophobicContact CG1-CB 4.04Å; V84-L241 HydrophobicContact CG2-CB 4.12Å; V84-L241 HydrophobicContact CG2-CD1 4.28Å
85L93.3Very high94.6Very high2 Ų216.8 Ų16.81%0.019%0.085CC..Hα-helixtrans-60.4-28.9173.1-72159.1000112.3V81 D82 G87 I126 H129 I223V81-L85 HydrophobicContact CG1-CD1 4.24Å; V81-L85 PolarHBondContact O-N 2.95Å; D82-L85 PolarHBondContact O-N 3.46Å; L85-G87 VanDerWaalsContact C-N 3.32Å; L85-I126 HydrophobicContact CD2-CG1 4.42Å; L85-I126 HydrophobicContact CD2-CG2 4.32Å; L85-H129 HydrophobicContact CD1-CB 3.76Å; L85-H129 HydrophobicContact CD2-CB 4.22Å; L85-I223 HydrophobicContact CD2-CD1 3.93Å; L85-I223 HydrophobicContact CG-CD1 4.36Å
86Q91.9Very high94.8Very high92 Ų9215.1 Ų15.143%0.438%0.078SC..THydrogen-bonded Turntrans-843.5172.3-60.7-57.5-31.100114.5D82 S83 V84 F88 V346D82-Q86 WeakPolarHBondContact O-CG 3.35Å; D82-Q86 PolarHBondContact O-N 2.92Å; S83-Q86 PolarHBondContact O-N 2.83Å; V84-Q86 PolarHBondContact O-N 3.35Å; Q86-F88 HydrophobicContact CB-CD2 4.48Å; Q86-V346 WeakPolarHBondContact O-CG1 3.39Å
87G92.1Very high94.6Very high1 Ų115.6 Ų15.61%0.018%0.079CC..THydrogen-bonded Turntrans92.313.5175.800000116.1S83 V84 L85 N347S83-G87 PolarHBondContact O-N 3.45Å; V84-G87 PolarHBondContact O-N 2.97Å; L85-G87 VanDerWaalsContact C-N 3.32Å; G87-N347 PolarHBondContact O-N 2.72Å; G87-N347 PolarHBondContact O-ND2 3.04Å
88F94.1Very high94.2Very high42 Ų4217.6 Ų17.618%0.1849%0.091CC..BIsolated β-bridgetrans-81155.9167.1-69.6-93000111.2S83 V84 Q86 G239 P344 R345 V346S83-F88 WeakPolarHBondContact O-CB 3.35Å; S83-F88 WeakPolarHBondContact O-CD2 3.32Å; S83-F88 PolarHBondContact O-N 2.95Å; V84-F88 WeakPolarHBondContact CA-O 3.47Å; Q86-F88 HydrophobicContact CB-CD2 4.48Å; F88-G239 WeakPolarHBondContact O-CA 3.18Å; F88-P344 HydrophobicContact CD1-CB 3.94Å; F88-P344 HydrophobicContact CE1-CB 4.25Å; F88-R345 WeakPolarHBondContact CD1-O 3.22Å; F88-R345 VanDerWaalsContact CE1-C 3.48Å; F88-V346 HydrophobicContact CD2-CG2 4.08Å; F88-V346 HydrophobicContact CE1-CG2 4.13Å; F88-V346 HydrophobicContact CE2-CG2 3.58Å; F88-V346 HydrophobicContact CZ-CG2 3.61Å
89N94.7Very high93.8Very high25 Ų2519.1 Ų19.113%0.13411%0.114CC..  trans-76.9139.9160.8-61.5-39.5000110.3K240 N308 A309 K310 N347N89-K240 CarbonylContact C-O 3.55Å; N89-K240 WeakPolarHBondContact CA-O 3.47Å; N89-K240 PolarHBondContact OD1-N 3.43Å; N89-N308 WeakPolarHBondContact CB-O 3.42Å; N89-N308 PolarHBondContact ND2-O 2.94Å; N89-A309 HydrophobicContact CB-CB 3.73Å; N89-A309 WeakPolarHBondContact O-CA 3.05Å; N89-K310 PolarHBondContact O-N 2.95Å; N89-N347 PolarHBondContact ND2-ND2 3.21Å; N89-N347 PolarHBondContact OD1-ND2 3.11Å
90G96.5Very high93.7Very high0 Ų017 Ų170%010%0.101CC..EExtended strand (participates in β ladder)trans-132.1139.8177.400000111.1K240 L241 N242 K310G90-K240 PolarHBondContact N-O 2.68Å; G90-L241 CarbonylContact O-C 3.4Å; G90-L241 VanDerWaalsContact O-CA 3.29Å; G90-L241 WeakPolarHBondContact O-CA 3.19Å; G90-N242 PolarHBondContact O-N 2.9Å; G90-K310 CarbonylContact C-O 3.55Å; G90-K310 VanDerWaalsContact CA-O 3.31Å; G90-K310 WeakPolarHBondContact CA-O 3.21Å
91T97.9Very high93.5Very high0 Ų017.7 Ų17.70%011%0.108CC..EExtended strand (participates in β ladder)trans-132.6130.3173.7-64.20000110.5F93 N242 V244 L301 S304 K310 T311 V312T91-F93 HydrophobicContact CG2-CD1 4.31Å; T91-N242 CarbonylContact C-O 3.54Å; T91-N242 WeakPolarHBondContact CA-O 3.25Å; T91-N242 HydrophobicContact CG2-CB 4.14Å; T91-N242 PolarHBondContact OG1-ND2 3.02Å; T91-V244 HydrophobicContact CG2-CG2 4.35Å; T91-L301 HydrophobicContact CG2-CD2 4.28Å; T91-S304 WeakPolarHBondContact CB-OG 3.1Å; T91-S304 PolarHBondContact OG1-OG 3.23Å; T91-K310 PolarHBondContact N-O 3.06Å; T91-T311 HydrophobicContact CG2-CG2 4.35Å; T91-T311 CarbonylContact O-C 3.55Å; T91-T311 WeakPolarHBondContact O-CA 3.34Å; T91-V312 PolarHBondContact O-N 3.44Å
92I98.3Very high93.4Very high0 Ų018.2 Ų18.20%011%0.111CC..EExtended strand (participates in β ladder)trans-117.5122.5169.5-52.2178.5000107.2F77 L80 M106 V118 L241 N242 L243 V244 V312 V314F77-I92 HydrophobicContact CB-CD1 3.96Å; F77-I92 HydrophobicContact CD1-CD1 3.81Å; F77-I92 HydrophobicContact CD1-CG1 4.45Å; F77-I92 HydrophobicContact CD1-CG2 4.07Å; F77-I92 HydrophobicContact CE1-CG2 3.84Å; F77-I92 HydrophobicContact CG-CD1 3.99Å; F77-I92 HydrophobicContact CZ-CG2 4.45Å; L80-I92 HydrophobicContact CD2-CD1 3.82Å; L80-I92 HydrophobicContact CD2-CG1 3.26Å; I92-M106 HydrophobicContact CG2-SD 4.44Å; I92-V118 HydrophobicContact CD1-CG2 3.58Å; I92-V118 HydrophobicContact CG2-CG1 4.49Å; I92-L241 HydrophobicContact CG1-CD1 4.42Å; I92-N242 PolarHBondContact N-O 3.23Å; I92-L243 HydrophobicContact CB-CD2 4.27Å; I92-L243 HydrophobicContact CD1-CD2 4.05Å; I92-L243 HydrophobicContact CG1-CD2 4.48Å; I92-V244 PolarHBondContact O-N 3.18Å; I92-V312 WeakPolarHBondContact CA-O 3.44Å; I92-V314 HydrophobicContact CG2-CG2 4.33Å
93F96.6Very high93.3Very high2 Ų218.5 Ų18.51%0.00911%0.114CC..EExtended strand (participates in β ladder)trans-128.3132.2175.669.8-89.8000112.6T91 V244 L246 L305 T311 V312 M313 V314T91-F93 HydrophobicContact CG2-CD1 4.31Å; F93-V244 WeakPolarHBondContact CA-O 3.43Å; F93-V244 HydrophobicContact CB-CB 3.66Å; F93-V244 HydrophobicContact CB-CG1 4.06Å; F93-V244 HydrophobicContact CB-CG2 4.31Å; F93-L246 HydrophobicContact CD2-CD1 3.86Å; F93-L305 HydrophobicContact CE1-CD2 4.3Å; F93-L305 HydrophobicContact CZ-CD2 4.44Å; F93-T311 HydrophobicContact CD1-CG2 3.99Å; F93-T311 HydrophobicContact CE1-CG2 3.68Å; F93-V312 PolarHBondContact N-O 2.76Å; F93-M313 HydrophobicContact CD2-CG 4.16Å; F93-M313 HydrophobicContact CE1-CB 3.9Å; F93-M313 HydrophobicContact CE1-CG 4.41Å; F93-M313 HydrophobicContact CE2-CB 3.9Å; F93-M313 HydrophobicContact CE2-CE 4.44Å; F93-M313 HydrophobicContact CE2-CG 3.47Å; F93-M313 VanDerWaalsContact CE2-CG 3.47Å; F93-M313 HydrophobicContact CE2-SD 3.97Å; F93-M313 HydrophobicContact CZ-CB 3.55Å; F93-M313 HydrophobicContact CZ-CG 3.63Å; F93-M313 HydrophobicContact CZ-SD 4.04Å; F93-V314 PolarHBondContact O-N 2.78Å
94A96.3Very high93.3Very high0 Ų022.4 Ų22.40%013%0.127CC..EExtended strand (participates in β ladder)trans-93128.5173.400000110.5K102 M106 V244 L246 V314A94-K102 HydrophobicContact CB-CB 3.88Å; A94-K102 HydrophobicContact CB-CG 4.21Å; A94-M106 HydrophobicContact CB-CG 3.68Å; A94-M106 HydrophobicContact CB-SD 3.81Å; A94-V244 PolarHBondContact N-O 3.43Å; A94-L246 VanDerWaalsContact O-CB 3.3Å; A94-L246 WeakPolarHBondContact O-CB 3.47Å; A94-L246 WeakPolarHBondContact O-CG 3.46Å; A94-L246 PolarHBondContact O-N 2.8Å; A94-V314 WeakPolarHBondContact CA-O 3.43Å
95Y95.2Very high93.3Very high10 Ų1022.4 Ų22.44%0.03913%0.127CC..EExtended strand (participates in β ladder)trans-132.5149.3-175.6178.2-88.1000111.1L246 L272 M313 V314 N316 T330 Y333Y95-L246 HydrophobicContact CD2-CD1 3.82Å; Y95-L246 HydrophobicContact CG-CD1 4.47Å; Y95-L272 HydrophobicContact CD2-CD2 4.43Å; Y95-L272 HydrophobicContact CE2-CD2 4.19Å; Y95-M313 HydrophobicContact CD1-CE 3.54Å; Y95-M313 HydrophobicContact CE1-CE 4.4Å; Y95-M313 HydrophobicContact CG-CE 3.78Å; Y95-V314 PolarHBondContact N-O 2.65Å; Y95-N316 PolarHBondContact O-N 2.97Å; Y95-T330 HydrophobicContact CD1-CG2 4.11Å; Y95-T330 HydrophobicContact CE1-CG2 4.25Å; Y95-Y333 HydrophobicContact CD1-CD1 4.14Å; Y95-Y333 HydrophobicContact CD1-CE1 4.47Å; Y95-Y333 HydrophobicContact CD2-CE1 4.18Å; Y95-Y333 AromaticContact CE1-CD1 3.78Å; Y95-Y333 HydrophobicContact CE1-CD1 3.78Å; Y95-Y333 HydrophobicContact CE1-CD2 4.48Å; Y95-Y333 HydrophobicContact CE1-CE1 4.22Å; Y95-Y333 AromaticContact CE1-CG 3.92Å; Y95-Y333 HydrophobicContact CE1-CG 3.92Å; Y95-Y333 HydrophobicContact CE2-CD1 4.29Å; Y95-Y333 AromaticContact CE2-CE1 3.9Å; Y95-Y333 HydrophobicContact CE2-CE1 3.9Å; Y95-Y333 HydrophobicContact CE2-CE2 4.33Å; Y95-Y333 AromaticContact CE2-CZ 3.93Å; Y95-Y333 HydrophobicContact CG-CE1 4.47Å; Y95-Y333 AromaticContact CZ-CD1 3.86Å; Y95-Y333 AromaticContact CZ-CE1 3.93Å; Y95-Y333 AromaticContact CZ-CG 3.9Å
96G92.5Very high93.4Very high0 Ų022.3 Ų22.30%013%0.127CC..SBendtrans137.4-177.7176.100000112.9K102 S249G96-K102 PolarHBondContact O-NZ 3.22Å; G96-S249 WeakPolarHBondContact CA-OG 3.48Å; G96-S249 PolarHBondContact O-N 3.31Å; G96-S249 VanDerWaalsContact O-N 3.16Å; G96-S249 PolarHBondContact O-OG 3.35Å
97Q89Confident93.4Very high21 Ų2119.2 Ų19.210%0.09811%0.112CC..SBendtrans-60.2152.8-177.7-173.3-164.226.900112.1T100 K102 S249 E250 N323 E326Q97-T100 HydrophobicContact CB-CG2 3.69Å; Q97-T100 WeakPolarHBondContact O-CB 3.01Å; Q97-T100 WeakPolarHBondContact O-CG2 3.43Å; Q97-T100 PolarHBondContact O-N 2.78Å; Q97-T100 PolarHBondContact O-OG1 2.96Å; Q97-K102 PolarHBondContact O-NZ 3.36Å; Q97-K102 VanDerWaalsContact O-NZ 3.14Å; Q97-S249 PolarHBondContact N-OG 2.89Å; Q97-S249 VanDerWaalsContact N-OG 3.12Å; Q97-E250 WeakPolarHBondContact CA-OE2 3.3Å; Q97-E250 HydrophobicContact CG-CB 4.26Å; Q97-N323 PolarHBondContact NE2-OD1 3.03Å; Q97-N323 VanDerWaalsContact OE1-CG 3.23Å; Q97-N323 PolarHBondContact OE1-OD1 3.28Å; Q97-E326 HydrophobicContact CB-CB 4.14Å; Q97-E326 HydrophobicContact CG-CB 4.2Å; Q97-E326 HydrophobicContact CG-CG 4.24Å
98T87Confident93.4Very high43 Ų4320 Ų2026%0.26412%0.12SC..THydrogen-bonded Turntrans-53.7139.7167.9-70.20000111.8T100 S213 G248 E250T98-T100 VanDerWaalsContact C-N 3.27Å; T98-T100 PolarHBondContact O-N 2.87Å; T98-S213 WeakPolarHBondContact OG1-CB 3.42Å; T98-G248 WeakPolarHBondContact OG1-CA 3.48Å; T98-E250 WeakPolarHBondContact CB-OE1 3.25Å; T98-E250 PolarHBondContact N-OE2 3.19Å; T98-E250 PolarHBondContact OG1-OE1 3.41Å; T98-E250 PolarHBondContact OG1-OE2 3.32Å
99G85.3Confident93.1Very high54 Ų5420.9 Ų20.956%0.55713%0.128SC*.THydrogen-bonded Turntrans73.45.7-179.600000115.7R17R17-G99 PolarHBondContact NE-O 3.45Å; R17-G99 PolarHBondContact NH2-O 2.9Å
100T90.8Very high92.3Very high2 Ų226.4 Ų26.41%0.01215%0.147CC..SBendtrans-79.5-17.8173.556.20000114.2R17 Q97 T98 N316R17-T100 WeakPolarHBondContact CG-O 3.45Å; Q97-T100 HydrophobicContact CB-CG2 3.69Å; Q97-T100 WeakPolarHBondContact O-CB 3.01Å; Q97-T100 WeakPolarHBondContact O-CG2 3.43Å; Q97-T100 PolarHBondContact O-N 2.78Å; Q97-T100 PolarHBondContact O-OG1 2.96Å; T98-T100 VanDerWaalsContact C-N 3.27Å; T98-T100 PolarHBondContact O-N 2.87Å; T100-N316 WeakPolarHBondContact CB-O 3.36Å; T100-N316 WeakPolarHBondContact OG1-CB 3.31Å; T100-N316 PolarHBondContact OG1-O 2.9Å
101G91.5Very high91.2Very high17 Ų1730 Ų3018%0.17518%0.184CC..SBendtrans115.12417600000116.2Y104 T105G101-Y104 PolarHBondContact O-N 2.99Å; G101-T105 WeakPolarHBondContact O-CB 3.48Å; G101-T105 PolarHBondContact O-N 3.07Å; G101-T105 PolarHBondContact O-OG1 2.91Å
102K93.6Very high90.6Very high12 Ų1232 Ų325%0.05220%0.195CC..Hα-helixtrans-53.6-66.1173.3-60.6-170.4-65.1-800112.3A94 G96 Q97 Y104 T105 M106 D245 L246 A247 N316A94-K102 HydrophobicContact CB-CB 3.88Å; A94-K102 HydrophobicContact CB-CG 4.21Å; G96-K102 PolarHBondContact O-NZ 3.22Å; Q97-K102 PolarHBondContact O-NZ 3.36Å; Q97-K102 VanDerWaalsContact O-NZ 3.14Å; K102-Y104 VanDerWaalsContact C-N 3.26Å; K102-Y104 PolarHBondContact O-N 3.23Å; K102-T105 WeakPolarHBondContact O-CA 3.44Å; K102-T105 WeakPolarHBondContact O-CB 3.44Å; K102-T105 PolarHBondContact O-N 3.05Å; K102-M106 PolarHBondContact O-N 3.02Å; K102-D245 WeakPolarHBondContact CB-OD1 3.43Å; K102-L246 WeakPolarHBondContact CE-O 3.24Å; K102-A247 WeakPolarHBondContact CE-O 3.39Å; K102-A247 PolarHBondContact NZ-O 2.83Å; K102-N316 WeakPolarHBondContact CA-OD1 3.4Å; K102-N316 HydrophobicContact CG-CB 4.16Å
103T92.1Very high90Very high50 Ų5036.2 Ų36.231%0.30722%0.222SC..Hα-helixtrans-60.1-32.1177.1-410000112.9T105 M106 E107 G108 D245T103-T105 VanDerWaalsContact C-N 3.3Å; T103-T105 PolarHBondContact O-N 3.32Å; T103-M106 PolarHBondContact O-N 2.71Å; T103-E107 HydrophobicContact CG2-CB 4.43Å; T103-E107 PolarHBondContact O-N 3.35Å; T103-G108 PolarHBondContact O-N 2.89Å; T103-G108 VanDerWaalsContact O-N 3.17Å; T103-D245 WeakPolarHBondContact CA-OD1 3.02Å; T103-D245 WeakPolarHBondContact CB-OD2 3.26Å; T103-D245 WeakPolarHBondContact CG2-OD2 3.41Å; T103-D245 PolarHBondContact N-OD1 2.93Å; T103-D245 VanDerWaalsContact N-OD1 3.08Å; T103-D245 PolarHBondContact OG1-OD1 3.27Å; T103-D245 PolarHBondContact OG1-OD2 2.85Å
104Y93.9Very high89.5Confident96 Ų9642.6 Ų42.638%0.37625%0.252SS..Hα-helixtrans-66.5-31.4172179.6-94.6000112.5Q69 G101 K102 G108 V109Q69-Y104 PolarHBondContact NE2-O 2.74Å; G101-Y104 PolarHBondContact O-N 2.99Å; K102-Y104 VanDerWaalsContact C-N 3.26Å; K102-Y104 PolarHBondContact O-N 3.23Å; Y104-G108 WeakPolarHBondContact O-CA 3.37Å; Y104-G108 PolarHBondContact O-N 3.42Å; Y104-V109 HydrophobicContact CD2-CG2 4.33Å; Y104-V109 HydrophobicContact CE2-CG2 3.89Å
105T95.9Very high89.2Confident1 Ų146.5 Ų46.51%0.00627%0.269CS..Hα-helixtrans-77.2-41.3174.2-54.30000111.1R15 L72 F77 G101 K102 T103 G117 V118 V314 N316R15-T105 PolarHBondContact NH1-OG1 3.5Å; L72-T105 HydrophobicContact CD2-CG2 3.76Å; F77-T105 HydrophobicContact CZ-CG2 4.4Å; G101-T105 WeakPolarHBondContact O-CB 3.48Å; G101-T105 PolarHBondContact O-N 3.07Å; G101-T105 PolarHBondContact O-OG1 2.91Å; K102-T105 WeakPolarHBondContact O-CA 3.44Å; K102-T105 WeakPolarHBondContact O-CB 3.44Å; K102-T105 PolarHBondContact O-N 3.05Å; T103-T105 VanDerWaalsContact C-N 3.3Å; T103-T105 PolarHBondContact O-N 3.32Å; T105-G117 CarbonylContact O-C 3.59Å; T105-G117 VanDerWaalsContact O-CA 3.26Å; T105-G117 WeakPolarHBondContact O-CA 3.34Å; T105-V118 PolarHBondContact O-N 2.94Å; T105-V314 HydrophobicContact CG2-CG1 4.18Å; T105-N316 PolarHBondContact OG1-ND2 2.82Å
106M95.4Very high89.1Confident1 Ų149.1 Ų49.11%0.00528%0.279CS..Hα-helixtrans-72.4-57.4-178.4-62-52.7-66.500112.9I92 A94 K102 T103 G117 V118 I119 L243 D245I92-M106 HydrophobicContact CG2-SD 4.44Å; A94-M106 HydrophobicContact CB-CG 3.68Å; A94-M106 HydrophobicContact CB-SD 3.81Å; K102-M106 PolarHBondContact O-N 3.02Å; T103-M106 PolarHBondContact O-N 2.71Å; M106-G117 CarbonylContact O-C 3.6Å; M106-V118 HydrophobicContact CE-CG1 3.87Å; M106-V118 PolarHBondContact O-N 3.47Å; M106-V118 VanDerWaalsContact O-N 3.11Å; M106-V118 HydrophobicContact SD-CG1 3.61Å; M106-I119 HydrophobicContact CB-CD1 3.95Å; M106-I119 HydrophobicContact CB-CG1 4.44Å; M106-I119 HydrophobicContact CE-CD1 4.29Å; M106-I119 HydrophobicContact CE-CG1 4.2Å; M106-I119 VanDerWaalsContact O-CB 3.31Å; M106-I119 WeakPolarHBondContact O-CB 3.32Å; M106-I119 VanDerWaalsContact O-CG1 3.29Å; M106-I119 WeakPolarHBondContact O-CG1 3.2Å; M106-I119 PolarHBondContact O-N 3.26Å; M106-L243 HydrophobicContact CE-CB 3.88Å; M106-L243 HydrophobicContact CE-CD2 4.1Å; M106-D245 HydrophobicContact CB-CB 4.29Å; M106-D245 HydrophobicContact CG-CB 4.01Å
107E92.9Very high89.2Confident27 Ų2749.1 Ų49.113%0.12628%0.279CS..THydrogen-bonded Turntrans-98.6-41.7-177.3177.4169.8159.500112.6T103 R110 G117 M194 N198T103-E107 HydrophobicContact CG2-CB 4.43Å; T103-E107 PolarHBondContact O-N 3.35Å; E107-R110 IonicContact OE1-CZ 3.95Å; E107-R110 IonicContact OE1-NE 2.71Å; E107-R110 PolarHBondContact OE1-NE 3.47Å; E107-R110 IonicContact OE1-NH2 3.11Å; E107-R110 PolarHBondContact OE1-NH2 2.9Å; E107-R110 IonicContact OE2-NH2 2.82Å; E107-G117 WeakPolarHBondContact O-CA 3.18Å; E107-G117 PolarHBondContact O-N 3.17Å; E107-M194 HydrophobicContact CB-CE 3.82Å; E107-M194 HydrophobicContact CG-CE 3.57Å; E107-N198 VanDerWaalsContact CD-ND2 3.28Å; E107-N198 PolarHBondContact OE1-ND2 2.62Å; E107-N198 PolarHBondContact OE2-ND2 2.79Å
108G92Very high89.6Confident16 Ų1648.3 Ų48.317%0.16528%0.275CS..BIsolated β-bridgetrans75.7-147.9-175.800000113.3T103 Y104 K115T103-G108 PolarHBondContact O-N 2.89Å; T103-G108 VanDerWaalsContact O-N 3.17Å; Y104-G108 WeakPolarHBondContact O-CA 3.37Å; Y104-G108 PolarHBondContact O-N 3.42Å; G108-K115 CarbonylContact C-O 3.55Å; G108-K115 VanDerWaalsContact CA-O 3.23Å; G108-K115 WeakPolarHBondContact CA-O 3.4Å
109V87.6Confident90Very high61 Ų6146.6 Ų46.637%0.3727%0.265SS..  trans-103.5122.8178-178.10000109.6Y104 D112 K115Y104-V109 HydrophobicContact CD2-CG2 4.33Å; Y104-V109 HydrophobicContact CE2-CG2 3.89Å; V109-D112 HydrophobicContact CB-CB 4.2Å; V109-D112 HydrophobicContact CG1-CB 4.02Å; V109-K115 HydrophobicContact CB-CB 3.8Å; V109-K115 HydrophobicContact CG2-CB 3.89Å; V109-K115 HydrophobicContact CG2-CD 4.07Å; V109-K115 PolarHBondContact N-O 3.29Å
110R77.3Confident90.4Very high142 Ų14244.6 Ų44.654%0.53624%0.242SC..THydrogen-bonded Turntrans-63.7138.5176.7-61.3-171-168.3167.514.8110.8E107 D112 N195 N198E107-R110 IonicContact OE1-CZ 3.95Å; E107-R110 IonicContact OE1-NE 2.71Å; E107-R110 PolarHBondContact OE1-NE 3.47Å; E107-R110 IonicContact OE1-NH2 3.11Å; E107-R110 PolarHBondContact OE1-NH2 2.9Å; E107-R110 IonicContact OE2-NH2 2.82Å; R110-D112 PolarHBondContact O-N 2.91Å; R110-N195 PolarHBondContact NH1-OD1 3.21Å; R110-N198 PolarHBondContact NH2-ND2 3.49Å; R110-N198 VanDerWaalsContact NH2-ND2 3.11Å
111G74.2Confident90.6Very high74 Ų7445.7 Ų45.776%0.76325%0.248SC*.THydrogen-bonded Turntrans77.7-7.2176.600000115.8P113G111-P113 WeakPolarHBondContact O-CD 3.47Å
112D86.4Confident90.8Very high43 Ų4344.9 Ų44.923%0.2324%0.239CC..  trans-107.1104.1178.3-177-28.4000110.1V109 R110 E114 K115 R116V109-D112 HydrophobicContact CB-CB 4.2Å; V109-D112 HydrophobicContact CG1-CB 4.02Å; R110-D112 PolarHBondContact O-N 2.91Å; D112-E114 VanDerWaalsContact C-N 3.28Å; D112-E114 PolarHBondContact O-N 2.87Å; D112-E114 PolarHBondContact OD1-N 3.42Å; D112-E114 VanDerWaalsContact OD1-N 3.12Å; D112-K115 HydrophobicContact CB-CB 4.13Å; D112-K115 PolarHBondContact O-N 3.17Å; D112-K115 VanDerWaalsContact O-N 3.09Å; D112-K115 PolarHBondContact OD1-N 3.38Å; D112-K115 IonicContact OD1-NZ 2.79Å; D112-K115 VanDerWaalsContact OD2-CD 3.3Å; D112-K115 WeakPolarHBondContact OD2-CD 3.34Å; D112-K115 WeakPolarHBondContact OD2-CE 3.2Å; D112-K115 IonicContact OD2-NZ 3.95Å; D112-K115 PolarHBondContact OD2-NZ 3.43Å; D112-R116 PolarHBondContact O-N 3Å; D112-R116 VanDerWaalsContact O-N 3.15Å
113P83.8Confident90.9Very high89 Ų8944.3 Ų44.358%0.57824%0.237SC*.G310 helixtrans-57.5-34.7-176.4-26.235.9000114.6G111 K115G111-P113 WeakPolarHBondContact O-CD 3.47Å; P113-K115 VanDerWaalsContact C-N 3.28Å; P113-K115 PolarHBondContact O-N 3.27Å
114E86.8Confident90.9Very high136 Ų13645.8 Ų45.864%0.63624%0.243SC*.G310 helixtrans-74.4-23-179.5-61.2-163.6148.500112.6D112D112-E114 VanDerWaalsContact C-N 3.28Å; D112-E114 PolarHBondContact O-N 2.87Å; D112-E114 PolarHBondContact OD1-N 3.42Å; D112-E114 VanDerWaalsContact OD1-N 3.12Å
115K90.9Very high90.8Very high81 Ų8141.8 Ų41.835%0.35223%0.228SC..G310 helixtrans-107.95.4-175-61.1-172.8-164.468.30114.2Q69 G108 V109 D112 P113Q69-K115 PolarHBondContact NE2-O 2.99Å; G108-K115 CarbonylContact C-O 3.55Å; G108-K115 VanDerWaalsContact CA-O 3.23Å; G108-K115 WeakPolarHBondContact CA-O 3.4Å; V109-K115 HydrophobicContact CB-CB 3.8Å; V109-K115 HydrophobicContact CG2-CB 3.89Å; V109-K115 HydrophobicContact CG2-CD 4.07Å; V109-K115 PolarHBondContact N-O 3.29Å; D112-K115 HydrophobicContact CB-CB 4.13Å; D112-K115 PolarHBondContact O-N 3.17Å; D112-K115 VanDerWaalsContact O-N 3.09Å; D112-K115 PolarHBondContact OD1-N 3.38Å; D112-K115 IonicContact OD1-NZ 2.79Å; D112-K115 VanDerWaalsContact OD2-CD 3.3Å; D112-K115 WeakPolarHBondContact OD2-CD 3.34Å; D112-K115 WeakPolarHBondContact OD2-CE 3.2Å; D112-K115 IonicContact OD2-NZ 3.95Å; D112-K115 PolarHBondContact OD2-NZ 3.43Å; P113-K115 VanDerWaalsContact C-N 3.28Å; P113-K115 PolarHBondContact O-N 3.27Å
116R92.6Very high90.7Very high65 Ų6541.8 Ų41.825%0.24523%0.228CC..BIsolated β-bridgetrans-54.5131.9170.3-74.7178.9-177.4-121.5-4.8111.5Q69 D112 P120 N121 E191Q69-R116 WeakPolarHBondContact CB-O 3.3Å; Q69-R116 WeakPolarHBondContact CG-O 3.37Å; D112-R116 PolarHBondContact O-N 3Å; D112-R116 VanDerWaalsContact O-N 3.15Å; R116-P120 HydrophobicContact CB-CB 4.47Å; R116-P120 HydrophobicContact CB-CG 3.94Å; R116-P120 HydrophobicContact CG-CB 4.48Å; R116-P120 HydrophobicContact CG-CG 4.32Å; R116-N121 PolarHBondContact O-ND2 3.23Å; R116-E191 IonicContact CZ-OE1 2.81Å; R116-E191 IonicContact NH1-OE1 3.25Å; R116-E191 PolarHBondContact NH1-OE1 2.97Å; R116-E191 IonicContact NH2-OE1 3.94Å
117G95Very high90.6Very high1 Ų142.7 Ų42.71%0.0123%0.231CC..  trans-79.3-174.7176.800000113.8T105 M106 E107 I119 P120 N121T105-G117 CarbonylContact O-C 3.59Å; T105-G117 VanDerWaalsContact O-CA 3.26Å; T105-G117 WeakPolarHBondContact O-CA 3.34Å; M106-G117 CarbonylContact O-C 3.6Å; E107-G117 WeakPolarHBondContact O-CA 3.18Å; E107-G117 PolarHBondContact O-N 3.17Å; G117-I119 VanDerWaalsContact C-N 3.31Å; G117-I119 PolarHBondContact O-N 2.97Å; G117-P120 WeakPolarHBondContact O-CD 3.44Å; G117-P120 WeakPolarHBondContact O-CG 3.46Å; G117-N121 WeakPolarHBondContact O-CB 3.47Å; G117-N121 PolarHBondContact O-N 3.44Å; G117-N121 PolarHBondContact O-ND2 3.42Å
118V96.1Very high90.4Very high3 Ų343 Ų432%0.01824%0.235CC..Hα-helixtrans-62.8-33.6-178.957.30000113.6Y73 F77 I92 T105 M106 S122 L243Y73-V118 HydrophobicContact CD2-CB 4.39Å; Y73-V118 HydrophobicContact CD2-CG2 3.98Å; Y73-V118 HydrophobicContact CE2-CG2 4.01Å; F77-V118 HydrophobicContact CB-CG2 3.81Å; F77-V118 HydrophobicContact CD1-CG2 4.34Å; F77-V118 HydrophobicContact CD2-CB 3.54Å; F77-V118 HydrophobicContact CD2-CG1 4.48Å; F77-V118 HydrophobicContact CD2-CG2 3.32Å; F77-V118 HydrophobicContact CE2-CB 3.69Å; F77-V118 HydrophobicContact CE2-CG1 4.27Å; F77-V118 HydrophobicContact CE2-CG2 3.93Å; F77-V118 HydrophobicContact CG-CB 4.28Å; F77-V118 HydrophobicContact CG-CG2 3.58Å; I92-V118 HydrophobicContact CD1-CG2 3.58Å; I92-V118 HydrophobicContact CG2-CG1 4.49Å; T105-V118 PolarHBondContact O-N 2.94Å; M106-V118 HydrophobicContact CE-CG1 3.87Å; M106-V118 PolarHBondContact O-N 3.47Å; M106-V118 VanDerWaalsContact O-N 3.11Å; M106-V118 HydrophobicContact SD-CG1 3.61Å; V118-S122 VanDerWaalsContact O-CB 3.3Å; V118-S122 WeakPolarHBondContact O-CB 3.42Å; V118-S122 PolarHBondContact O-N 2.9Å; V118-S122 PolarHBondContact O-OG 3.12Å; V118-L243 HydrophobicContact CG1-CD2 4.25Å; V118-L243 HydrophobicContact CG2-CD2 4.09Å
119I95.6Very high90.3Very high7 Ų744.7 Ų44.74%0.03624%0.239CC..Hα-helixtrans-61.3-62.4178.9-62.5170.6000110.9M106 G117 N121 S122 F123 M194 L243M106-I119 HydrophobicContact CB-CD1 3.95Å; M106-I119 HydrophobicContact CB-CG1 4.44Å; M106-I119 HydrophobicContact CE-CD1 4.29Å; M106-I119 HydrophobicContact CE-CG1 4.2Å; M106-I119 VanDerWaalsContact O-CB 3.31Å; M106-I119 WeakPolarHBondContact O-CB 3.32Å; M106-I119 VanDerWaalsContact O-CG1 3.29Å; M106-I119 WeakPolarHBondContact O-CG1 3.2Å; M106-I119 PolarHBondContact O-N 3.26Å; G117-I119 VanDerWaalsContact C-N 3.31Å; G117-I119 PolarHBondContact O-N 2.97Å; I119-N121 VanDerWaalsContact C-N 3.32Å; I119-N121 PolarHBondContact O-N 2.66Å; I119-S122 WeakPolarHBondContact O-CB 3.4Å; I119-S122 PolarHBondContact O-N 2.77Å; I119-S122 PolarHBondContact O-OG 2.6Å; I119-F123 HydrophobicContact CG2-CE1 3.63Å; I119-F123 HydrophobicContact CG2-CE2 3.91Å; I119-F123 HydrophobicContact CG2-CZ 3.25Å; I119-F123 WeakPolarHBondContact O-CD1 3.23Å; I119-F123 PolarHBondContact O-N 3.31Å; I119-M194 HydrophobicContact CB-CE 4.05Å; I119-M194 HydrophobicContact CB-SD 4.46Å; I119-M194 HydrophobicContact CD1-CE 3.95Å; I119-M194 HydrophobicContact CG2-CE 3.68Å; I119-M194 HydrophobicContact CG2-SD 3.58Å; I119-M194 VanDerWaalsContact CG2-SD 3.58Å; I119-L243 HydrophobicContact CD1-CB 4.3Å; I119-L243 HydrophobicContact CG1-CB 3.85Å; I119-L243 HydrophobicContact CG1-CD1 4.09Å; I119-L243 HydrophobicContact CG1-CD2 4.06Å; I119-L243 HydrophobicContact CG1-CG 4.21Å; I119-L243 HydrophobicContact CG2-CD1 4.41Å
120P94.4Very high90.3Very high13 Ų1342 Ų428%0.08422%0.223CC..Hα-helixtrans-63.6-32.7179.823.6-34.2000113.8R116 G117 S122 F123 D124R116-P120 HydrophobicContact CB-CB 4.47Å; R116-P120 HydrophobicContact CB-CG 3.94Å; R116-P120 HydrophobicContact CG-CB 4.48Å; R116-P120 HydrophobicContact CG-CG 4.32Å; G117-P120 WeakPolarHBondContact O-CD 3.44Å; G117-P120 WeakPolarHBondContact O-CG 3.46Å; P120-S122 VanDerWaalsContact C-N 3.33Å; P120-F123 WeakPolarHBondContact O-CB 3.36Å; P120-F123 PolarHBondContact O-N 3.06Å; P120-D124 PolarHBondContact O-N 3.1Å
121N94.4Very high90.7Very high24 Ų2437.8 Ų37.813%0.12822%0.215CC..Hα-helixtrans-67.9-33.1174-69.8-35.3000112Y73 R116 G117 I119 F123 H125Y73-N121 HydrophobicContact CD1-CB 4.28Å; Y73-N121 HydrophobicContact CD2-CB 3.46Å; Y73-N121 VanDerWaalsContact CD2-CB 3.46Å; Y73-N121 HydrophobicContact CE1-CB 4.42Å; Y73-N121 HydrophobicContact CE2-CB 3.63Å; Y73-N121 HydrophobicContact CG-CB 3.83Å; R116-N121 PolarHBondContact O-ND2 3.23Å; G117-N121 WeakPolarHBondContact O-CB 3.47Å; G117-N121 PolarHBondContact O-N 3.44Å; G117-N121 PolarHBondContact O-ND2 3.42Å; I119-N121 VanDerWaalsContact C-N 3.32Å; I119-N121 PolarHBondContact O-N 2.66Å; N121-F123 VanDerWaalsContact C-N 3.34Å; N121-H125 WeakPolarHBondContact O-CB 3.41Å; N121-H125 PolarHBondContact O-N 3.27Å; N121-H125 VanDerWaalsContact O-N 3.07Å
122S96Very high91.1Very high0 Ų037.4 Ų37.40%019%0.19CC..Hα-helixtrans-66.3-34.9173.176.70000112.7Y73 V118 I119 P120 I126Y73-S122 WeakPolarHBondContact OH-CA 3.34Å; V118-S122 VanDerWaalsContact O-CB 3.3Å; V118-S122 WeakPolarHBondContact O-CB 3.42Å; V118-S122 PolarHBondContact O-N 2.9Å; V118-S122 PolarHBondContact O-OG 3.12Å; I119-S122 WeakPolarHBondContact O-CB 3.4Å; I119-S122 PolarHBondContact O-N 2.77Å; I119-S122 PolarHBondContact O-OG 2.6Å; P120-S122 VanDerWaalsContact C-N 3.33Å; S122-I126 WeakPolarHBondContact O-CB 3.28Å; S122-I126 VanDerWaalsContact O-CD1 3.3Å; S122-I126 WeakPolarHBondContact O-CD1 3.46Å; S122-I126 WeakPolarHBondContact O-CG1 3.38Å; S122-I126 PolarHBondContact O-N 2.9Å
123F95Very high91Very high0 Ų036 Ų360%018%0.183CC..Hα-helixtrans-61.9-51.6175.9-57.4-18.2000110.9I119 P120 N121 H125 I126 F127 V187 I190 E191 M194 F219 I221I119-F123 HydrophobicContact CG2-CE1 3.63Å; I119-F123 HydrophobicContact CG2-CE2 3.91Å; I119-F123 HydrophobicContact CG2-CZ 3.25Å; I119-F123 WeakPolarHBondContact O-CD1 3.23Å; I119-F123 PolarHBondContact O-N 3.31Å; P120-F123 WeakPolarHBondContact O-CB 3.36Å; P120-F123 PolarHBondContact O-N 3.06Å; N121-F123 VanDerWaalsContact C-N 3.34Å; F123-H125 PolarHBondContact O-N 3.31Å; F123-I126 PolarHBondContact O-N 2.86Å; F123-F127 VanDerWaalsContact O-CD2 3.28Å; F123-F127 WeakPolarHBondContact O-CD2 3.25Å; F123-F127 PolarHBondContact O-N 3.08Å; F123-V187 HydrophobicContact CB-CG1 4.25Å; F123-I190 HydrophobicContact CB-CG2 3.71Å; F123-I190 HydrophobicContact CD1-CD1 3.7Å; F123-I190 HydrophobicContact CD1-CG1 3.97Å; F123-I190 HydrophobicContact CD1-CG2 3.96Å; F123-I190 HydrophobicContact CD2-CG1 4.43Å; F123-I190 HydrophobicContact CD2-CG2 3.6Å; F123-I190 HydrophobicContact CE1-CD1 3.68Å; F123-I190 HydrophobicContact CE1-CG1 3.74Å; F123-I190 HydrophobicContact CE1-CG2 4.46Å; F123-I190 HydrophobicContact CE2-CG1 4.22Å; F123-I190 HydrophobicContact CE2-CG2 4.14Å; F123-I190 HydrophobicContact CG-CD1 4.37Å; F123-I190 HydrophobicContact CG-CG1 4.32Å; F123-I190 HydrophobicContact CG-CG2 3.49Å; F123-I190 VanDerWaalsContact CG-CG2 3.49Å; F123-I190 HydrophobicContact CZ-CD1 4.32Å; F123-I190 HydrophobicContact CZ-CG1 3.86Å; F123-E191 HydrophobicContact CD2-CG 3.97Å; F123-E191 HydrophobicContact CE2-CG 4.37Å; F123-M194 HydrophobicContact CE2-CB 4.2Å; F123-M194 HydrophobicContact CE2-SD 3.84Å; F123-M194 HydrophobicContact CZ-CB 4.27Å; F123-M194 HydrophobicContact CZ-SD 4.04Å; F123-F219 HydrophobicContact CE1-CD1 4.16Å; F123-F219 AromaticContact CE1-CE1 3.53Å; F123-F219 HydrophobicContact CE1-CE1 3.53Å; F123-F219 HydrophobicContact CE1-CZ 4.07Å; F123-F219 HydrophobicContact CZ-CD1 4.32Å; F123-F219 AromaticContact CZ-CE1 3.65Å; F123-F219 HydrophobicContact CZ-CE1 3.65Å; F123-F219 HydrophobicContact CZ-CE2 4.44Å; F123-F219 AromaticContact CZ-CZ 3.73Å; F123-F219 HydrophobicContact CZ-CZ 3.73Å; F123-I221 HydrophobicContact CD1-CD1 3.78Å; F123-I221 HydrophobicContact CE1-CD1 3.71Å
124D91.9Very high90.8Very high81 Ų8138.8 Ų38.843%0.43319%0.189SC..Hα-helixtrans-59.3-47.6179.2-168.28.4000111.2P120 I126 F127 T128P120-D124 PolarHBondContact O-N 3.1Å; D124-I126 PolarHBondContact O-N 3.08Å; D124-F127 PolarHBondContact O-N 2.77Å; D124-T128 WeakPolarHBondContact O-CB 3.24Å; D124-T128 PolarHBondContact O-N 2.94Å; D124-T128 PolarHBondContact O-OG1 3.26Å; D124-T128 PolarHBondContact OD1-OG1 3.19Å
125H92.9Very high90.4Very high13 Ų1339.6 Ų39.66%0.0620%0.197CC..Hα-helixtrans-59.3-46.2177.6-175-158000113Y73 R78 V81 D82 N121 F123 H129Y73-H125 HydrophobicContact CE1-CB 4.34Å; Y73-H125 VanDerWaalsContact OH-CB 3.28Å; Y73-H125 WeakPolarHBondContact OH-CB 3.46Å; Y73-H125 PolarHBondContact OH-ND1 2.82Å; R78-H125 PolarHBondContact NH1-CD2 3.07Å; R78-H125 VanDerWaalsContact NH1-CD2 3.29Å; R78-H125 PolarHBondContact NH1-NE2 2.91Å; R78-H125 VanDerWaalsContact NH1-NE2 3.14Å; V81-H125 WeakPolarHBondContact CG1-ND1 3.48Å; D82-H125 IonicContact OD1-CE1 2.74Å; D82-H125 PolarHBondContact OD1-CE1 2.98Å; D82-H125 IonicContact OD1-NE2 2.85Å; D82-H125 PolarHBondContact OD1-NE2 3.19Å; N121-H125 WeakPolarHBondContact O-CB 3.41Å; N121-H125 PolarHBondContact O-N 3.27Å; N121-H125 VanDerWaalsContact O-N 3.07Å; F123-H125 PolarHBondContact O-N 3.31Å; H125-H129 WeakPolarHBondContact O-CB 3.43Å; H125-H129 PolarHBondContact O-N 2.99Å
126I94Very high90.1Very high1 Ų137 Ų371%0.00519%0.186CC..Hα-helixtrans-62.3-51.8179.1-71.6161.9000111V81 L85 S122 F123 D124 T128 H129 I130 V140 I221 I223 L241V81-I126 HydrophobicContact CG1-CD1 4.27Å; V81-I126 HydrophobicContact CG1-CG1 3.76Å; L85-I126 HydrophobicContact CD2-CG1 4.42Å; L85-I126 HydrophobicContact CD2-CG2 4.32Å; S122-I126 WeakPolarHBondContact O-CB 3.28Å; S122-I126 VanDerWaalsContact O-CD1 3.3Å; S122-I126 WeakPolarHBondContact O-CD1 3.46Å; S122-I126 WeakPolarHBondContact O-CG1 3.38Å; S122-I126 PolarHBondContact O-N 2.9Å; F123-I126 PolarHBondContact O-N 2.86Å; D124-I126 PolarHBondContact O-N 3.08Å; I126-T128 PolarHBondContact O-N 3.31Å; I126-H129 PolarHBondContact O-N 2.86Å; I126-I130 HydrophobicContact CG2-CD1 3.77Å; I126-I130 VanDerWaalsContact O-CG1 3.25Å; I126-I130 WeakPolarHBondContact O-CG1 3.28Å; I126-I130 PolarHBondContact O-N 3Å; I126-V140 HydrophobicContact CG2-CG2 4.23Å; I126-I221 HydrophobicContact CD1-CD1 3.75Å; I126-I221 HydrophobicContact CD1-CG2 4.29Å; I126-I223 HydrophobicContact CD1-CD1 3.83Å; I126-I223 HydrophobicContact CG1-CD1 3.87Å; I126-I223 HydrophobicContact CG2-CD1 3.87Å; I126-L241 HydrophobicContact CD1-CD2 4.39Å
127F92Very high89.8Confident19 Ų1937 Ų378%0.08319%0.189CC..Hα-helixtrans-70.8-31.1-177.6-76.4-73.4000112.8F123 D124 I130 S131 V140 T184 V187 I190 L468F123-F127 VanDerWaalsContact O-CD2 3.28Å; F123-F127 WeakPolarHBondContact O-CD2 3.25Å; F123-F127 PolarHBondContact O-N 3.08Å; D124-F127 PolarHBondContact O-N 2.77Å; F127-I130 PolarHBondContact O-N 3Å; F127-S131 WeakPolarHBondContact O-CB 3.39Å; F127-S131 PolarHBondContact O-N 3.45Å; F127-S131 PolarHBondContact O-OG 3.3Å; F127-V140 HydrophobicContact CE1-CG2 4.4Å; F127-V140 HydrophobicContact CZ-CB 4.23Å; F127-V140 HydrophobicContact CZ-CG1 4.15Å; F127-V140 HydrophobicContact CZ-CG2 4.43Å; F127-T184 WeakPolarHBondContact CZ-O 3.34Å; F127-V187 HydrophobicContact CB-CG2 3.73Å; F127-V187 HydrophobicContact CD2-CG2 3.9Å; F127-V187 HydrophobicContact CG-CG2 4.1Å; F127-I190 HydrophobicContact CD2-CG2 4.33Å; F127-I190 HydrophobicContact CE2-CB 4.23Å; F127-I190 HydrophobicContact CE2-CD1 4.47Å; F127-I190 HydrophobicContact CE2-CG2 3.66Å; F127-L468 HydrophobicContact CD1-CD1 4.26Å; F127-L468 HydrophobicContact CE1-CD1 3.75Å
128T89.3Confident89.6Confident34 Ų3437 Ų3721%0.20919%0.189CC..Hα-helixtrans-68.5-37.8171.9-68.30000111.8D124 I126 S131 R132D124-T128 WeakPolarHBondContact O-CB 3.24Å; D124-T128 PolarHBondContact O-N 2.94Å; D124-T128 PolarHBondContact O-OG1 3.26Å; D124-T128 PolarHBondContact OD1-OG1 3.19Å; I126-T128 PolarHBondContact O-N 3.31Å; T128-S131 PolarHBondContact O-OG 3.23Å; T128-R132 WeakPolarHBondContact O-CD 3.32Å; T128-R132 WeakPolarHBondContact O-CG 3.32Å; T128-R132 PolarHBondContact O-N 2.91Å
129H89.3Confident89.3Confident51 Ų5136.9 Ų36.924%0.23619%0.188CC..Hα-helixtrans-63.7-47.8171.4-176.5-78.2000111.3L85 H125 I126 S131 R132 S133 Y138L85-H129 HydrophobicContact CD1-CB 3.76Å; L85-H129 HydrophobicContact CD2-CB 4.22Å; H125-H129 WeakPolarHBondContact O-CB 3.43Å; H125-H129 PolarHBondContact O-N 2.99Å; I126-H129 PolarHBondContact O-N 2.86Å; H129-S131 VanDerWaalsContact C-N 3.34Å; H129-S131 PolarHBondContact O-N 3.49Å; H129-R132 PolarHBondContact O-N 3.14Å; H129-S133 PolarHBondContact O-N 3.02Å; H129-Y138 PolarHBondContact CE1-OH 3.24Å
130I88.3Confident89.3Confident6 Ų636.6 Ų36.63%0.03119%0.187CC..Hα-helixtrans-60.2-42.2179.9-67.3167.9000111.4I126 F127 R132 S133 Y138 V140 L468 G470I126-I130 HydrophobicContact CG2-CD1 3.77Å; I126-I130 VanDerWaalsContact O-CG1 3.25Å; I126-I130 WeakPolarHBondContact O-CG1 3.28Å; I126-I130 PolarHBondContact O-N 3Å; F127-I130 PolarHBondContact O-N 3Å; I130-R132 PolarHBondContact O-N 3Å; I130-S133 PolarHBondContact O-OG 3.38Å; I130-Y138 HydrophobicContact CB-CD2 4.38Å; I130-Y138 HydrophobicContact CB-CG 4.44Å; I130-Y138 HydrophobicContact CD1-CD1 4.1Å; I130-Y138 HydrophobicContact CD1-CG 4.08Å; I130-Y138 HydrophobicContact CG1-CD1 3.78Å; I130-Y138 HydrophobicContact CG1-CD2 4Å; I130-Y138 HydrophobicContact CG1-CE1 4.15Å; I130-Y138 HydrophobicContact CG1-CE2 4.39Å; I130-Y138 HydrophobicContact CG1-CG 3.67Å; I130-Y138 HydrophobicContact CG2-CD2 3.95Å; I130-Y138 HydrophobicContact CG2-CG 4.1Å; I130-V140 HydrophobicContact CD1-CG2 3.41Å; I130-V140 VanDerWaalsContact CD1-CG2 3.41Å; I130-L468 HydrophobicContact CD1-CD1 4.26Å; I130-L468 HydrophobicContact CG2-CB 3.72Å; I130-L468 HydrophobicContact CG2-CD1 4.17Å; I130-G470 VanDerWaalsContact O-CA 3.25Å; I130-G470 WeakPolarHBondContact O-CA 3.28Å
131S85.5Confident89.3Confident53 Ų5337.7 Ų37.737%0.37119%0.189SC..Hα-helixtrans-64.8-26.7179.969.10000113.5F127 T128 H129 G471F127-S131 WeakPolarHBondContact O-CB 3.39Å; F127-S131 PolarHBondContact O-N 3.45Å; F127-S131 PolarHBondContact O-OG 3.3Å; T128-S131 PolarHBondContact O-OG 3.23Å; H129-S131 VanDerWaalsContact C-N 3.34Å; H129-S131 PolarHBondContact O-N 3.49Å; S131-G471 PolarHBondContact O-N 3.06Å
132R83.2Confident89.4Confident66 Ų6636.6 Ų36.625%0.24918%0.183CC..Hα-helixtrans-99.5-16.5-175-63.6162.298.6-172.529114.2T128 H129 I130 N479 K483 E486T128-R132 WeakPolarHBondContact O-CD 3.32Å; T128-R132 WeakPolarHBondContact O-CG 3.32Å; T128-R132 PolarHBondContact O-N 2.91Å; H129-R132 PolarHBondContact O-N 3.14Å; I130-R132 PolarHBondContact O-N 3Å; R132-N479 PolarHBondContact NH2-O 3.33Å; R132-K483 VanDerWaalsContact NH2-CB 3.26Å; R132-E486 IonicContact CZ-OE2 3.07Å; R132-E486 IonicContact NH1-OE2 3.7Å; R132-E486 PolarHBondContact NH1-OE2 3.13Å; R132-E486 IonicContact NH2-OE2 2.66Å
133S83.8Confident89.5Confident12 Ų1237 Ų378%0.08419%0.187CC..  trans-59.5151.3169.167.30000110.8H129 I130 Y138 G470 G471H129-S133 PolarHBondContact O-N 3.02Å; I130-S133 PolarHBondContact O-OG 3.38Å; S133-Y138 WeakPolarHBondContact OG-CE2 3.47Å; S133-G470 CarbonylContact O-C 3.57Å; S133-G470 WeakPolarHBondContact O-CA 3.31Å; S133-G471 PolarHBondContact O-N 3.44Å
134Q79.1Confident89.6Confident148 Ų14837.3 Ų37.369%0.69219%0.188SC*.SBendtrans-126.2148.9173.2-67.7-179.5-13.200107.7Q136Q134-Q136 PolarHBondContact O-N 3.4Å
135N79.2Confident89.7Confident153 Ų15333.7 Ų33.782%0.81817%0.168SC*.SBendtrans57.819.5177.7-50.5-24.7000115.3
136Q84.6Confident89.7Confident26 Ų2633.1 Ų33.112%0.12117%0.166CC..EExtended strand (participates in β ladder)trans-124.1139.9179.3-68.5174-7.900110.1Q134 Y138 S226 E227Q134-Q136 PolarHBondContact O-N 3.4Å; Q136-Y138 HydrophobicContact CB-CD2 4.28Å; Q136-Y138 HydrophobicContact CB-CE2 3.59Å; Q136-Y138 PolarHBondContact OE1-OH 2.98Å; Q136-S226 WeakPolarHBondContact CA-O 3.25Å; Q136-E227 HydrophobicContact CG-CB 4.13Å; Q136-E227 HydrophobicContact CG-CG 4.05Å; Q136-E227 VanDerWaalsContact NE2-CD 3.33Å; Q136-E227 PolarHBondContact NE2-OE1 3.17Å
137Q85.6Confident89.6Confident66 Ų6633.2 Ų33.231%0.30817%0.166SC..EExtended strand (participates in β ladder)trans-110132.3174.6-63.5-174.84.200109.9C225 S226 L468Q137-C225 CarbonylContact O-C 3.53Å; Q137-C225 WeakPolarHBondContact O-CA 3.32Å; Q137-S226 PolarHBondContact N-O 3.33Å; Q137-S226 PolarHBondContact O-N 3.44Å; Q137-L468 WeakPolarHBondContact CA-O 3.35Å
138Y90.4Very high89.3Confident1 Ų134 Ų340%0.00417%0.169CC..EExtended strand (participates in β ladder)trans-119.7144.6-178.7-70.9-96.9000112.3H129 I130 S133 Q136 I223 E224 C225 L468H129-Y138 PolarHBondContact CE1-OH 3.24Å; I130-Y138 HydrophobicContact CB-CD2 4.38Å; I130-Y138 HydrophobicContact CB-CG 4.44Å; I130-Y138 HydrophobicContact CD1-CD1 4.1Å; I130-Y138 HydrophobicContact CD1-CG 4.08Å; I130-Y138 HydrophobicContact CG1-CD1 3.78Å; I130-Y138 HydrophobicContact CG1-CD2 4Å; I130-Y138 HydrophobicContact CG1-CE1 4.15Å; I130-Y138 HydrophobicContact CG1-CE2 4.39Å; I130-Y138 HydrophobicContact CG1-CG 3.67Å; I130-Y138 HydrophobicContact CG2-CD2 3.95Å; I130-Y138 HydrophobicContact CG2-CG 4.1Å; S133-Y138 WeakPolarHBondContact OG-CE2 3.47Å; Q136-Y138 HydrophobicContact CB-CD2 4.28Å; Q136-Y138 HydrophobicContact CB-CE2 3.59Å; Q136-Y138 PolarHBondContact OE1-OH 2.98Å; Y138-I223 HydrophobicContact CD1-CG2 3.83Å; Y138-I223 HydrophobicContact CE1-CG2 4.28Å; Y138-E224 CarbonylContact C-O 3.53Å; Y138-E224 VanDerWaalsContact CA-O 3.3Å; Y138-E224 WeakPolarHBondContact CA-O 3.33Å; Y138-C225 HydrophobicContact CD1-CB 3.9Å; Y138-C225 HydrophobicContact CE1-CB 3.67Å; Y138-C225 VanDerWaalsContact CZ-SG 3.58Å; Y138-L468 PolarHBondContact N-O 3.46Å; Y138-L468 WeakPolarHBondContact O-CB 3.36Å; Y138-L468 PolarHBondContact O-N 3.13Å
139L91.3Very high88.9Confident0 Ų035.1 Ų35.10%017%0.172CC..EExtended strand (participates in β ladder)trans-128.3109.6168177.466000108.6V183 E224 L354 L355 F358L139-V183 HydrophobicContact CD1-CG1 3.65Å; L139-V183 HydrophobicContact CD1-CG2 4.12Å; L139-E224 HydrophobicContact CB-CB 4.32Å; L139-E224 PolarHBondContact N-O 2.88Å; L139-E224 PolarHBondContact O-N 3.41Å; L139-L354 HydrophobicContact CD2-CB 4.22Å; L139-L354 HydrophobicContact CD2-CD2 4.17Å; L139-L354 HydrophobicContact CD2-CG 4.15Å; L139-L355 HydrophobicContact CB-CB 4.29Å; L139-L355 HydrophobicContact CB-CD1 3.98Å; L139-L355 HydrophobicContact CB-CG 4.38Å; L139-L355 HydrophobicContact CD2-CB 4.18Å; L139-F358 HydrophobicContact CD1-CD2 4.32Å; L139-F358 HydrophobicContact CD1-CE2 4.02Å; L139-F358 HydrophobicContact CD2-CD2 3.82Å; L139-F358 HydrophobicContact CD2-CE2 3.77Å
140V94.9Very high88.9Confident1 Ų134.4 Ų34.41%0.00617%0.168CC..EExtended strand (participates in β ladder)trans-100.1129177.9-176.10000109.7I126 F127 I130 V183 T184 I221 T222 I223 L468I126-V140 HydrophobicContact CG2-CG2 4.23Å; F127-V140 HydrophobicContact CE1-CG2 4.4Å; F127-V140 HydrophobicContact CZ-CB 4.23Å; F127-V140 HydrophobicContact CZ-CG1 4.15Å; F127-V140 HydrophobicContact CZ-CG2 4.43Å; I130-V140 HydrophobicContact CD1-CG2 3.41Å; I130-V140 VanDerWaalsContact CD1-CG2 3.41Å; V140-V183 WeakPolarHBondContact O-CA 3.42Å; V140-T184 PolarHBondContact O-N 3.41Å; V140-I221 HydrophobicContact CG1-CG2 3.7Å; V140-T222 WeakPolarHBondContact CA-O 3.41Å; V140-I223 HydrophobicContact CG2-CG2 4.5Å; V140-L468 HydrophobicContact CG2-CD1 4.19Å
141R95.1Very high88.9Confident37 Ų3737.8 Ų37.814%0.1418%0.184CC..EExtended strand (participates in β ladder)trans-124.4141.2173.7-58.9-167.8-64-83.94.7111.5F182 V183 I221 T222 E224R141-F182 CarbonylContact C-O 3.55Å; R141-F182 VanDerWaalsContact CA-O 3.28Å; R141-F182 WeakPolarHBondContact CA-O 3.48Å; R141-V183 HydrophobicContact CG-CG2 4.13Å; R141-I221 CarbonylContact O-C 3.58Å; R141-I221 WeakPolarHBondContact O-CA 3.47Å; R141-T222 PolarHBondContact N-O 3.46Å; R141-T222 PolarHBondContact O-N 2.85Å; R141-E224 IonicContact CZ-OE1 2.73Å; R141-E224 IonicContact NH1-OE1 2.59Å; R141-E224 PolarHBondContact NH1-OE1 2.8Å; R141-E224 IonicContact NH1-OE2 2.93Å; R141-E224 PolarHBondContact NH1-OE2 3.12Å; R141-E224 IonicContact NH2-OE1 3.67Å; R141-E224 PolarHBondContact NH2-OE1 3.43Å
142A97Very high89.2Confident0 Ų035.3 Ų35.30%017%0.167CC..EExtended strand (participates in β ladder)trans-115.9134.5174.300000111S181 F182 T184 I190 V193 F219 V220A142-S181 WeakPolarHBondContact O-CA 3.33Å; A142-F182 PolarHBondContact N-O 2.88Å; A142-F182 PolarHBondContact O-N 3.45Å; A142-T184 HydrophobicContact CB-CG2 4.24Å; A142-I190 HydrophobicContact CB-CD1 4.03Å; A142-I190 HydrophobicContact CB-CG1 4.02Å; A142-V193 HydrophobicContact CB-CG1 3.99Å; A142-F219 HydrophobicContact CB-CE1 4.06Å; A142-F219 HydrophobicContact CB-CZ 3.84Å; A142-V220 WeakPolarHBondContact CA-O 3.26Å
143S96.8Very high89.6Confident10 Ų1033.8 Ų33.87%0.0716%0.161CC..EExtended strand (participates in β ladder)trans-128.6143.3169.6-69.30000108.5S180 S181 V220S143-S180 VanDerWaalsContact CB-O 3.32Å; S143-S180 WeakPolarHBondContact CB-O 3.39Å; S143-S180 PolarHBondContact OG-O 2.89Å; S143-S181 WeakPolarHBondContact OG-CA 3.43Å; S143-S181 VanDerWaalsContact OG-CB 3.27Å; S143-S181 WeakPolarHBondContact OG-CB 3.28Å; S143-S181 PolarHBondContact OG-OG 3.49Å; S143-V220 PolarHBondContact N-O 3.33Å; S143-V220 PolarHBondContact O-N 2.88Å
144Y96.8Very high90.2Very high6 Ų633.6 Ų33.62%0.02416%0.159CC..EExtended strand (participates in β ladder)trans-137.3122.4-178.8-165.3-171.6000110L155 L156 N198 A217 I218 F219Y144-L155 HydrophobicContact CD1-CB 4.34Å; Y144-L155 HydrophobicContact CD1-CD1 4.02Å; Y144-L155 HydrophobicContact CD2-CD1 3.82Å; Y144-L155 HydrophobicContact CE1-CD1 3.98Å; Y144-L155 HydrophobicContact CE2-CD1 3.81Å; Y144-L155 HydrophobicContact CG-CB 4.26Å; Y144-L155 HydrophobicContact CG-CD1 3.93Å; Y144-L155 WeakPolarHBondContact O-CB 3.46Å; Y144-L155 PolarHBondContact O-N 2.84Å; Y144-L156 HydrophobicContact CD1-CD2 4.48Å; Y144-N198 PolarHBondContact OH-OD1 2.72Å; Y144-A217 HydrophobicContact CE2-CB 3.93Å; Y144-I218 WeakPolarHBondContact CD2-O 3.09Å; Y144-F219 AromaticContact CD1-CD2 3.61Å; Y144-F219 HydrophobicContact CD1-CD2 3.61Å; Y144-F219 AromaticContact CD1-CE2 3.99Å; Y144-F219 HydrophobicContact CD1-CE2 3.99Å; Y144-F219 HydrophobicContact CD2-CB 3.93Å; Y144-F219 AromaticContact CD2-CD2 3.74Å; Y144-F219 HydrophobicContact CD2-CD2 3.74Å; Y144-F219 HydrophobicContact CD2-CG 4.3Å; Y144-F219 HydrophobicContact CE1-CD2 4.06Å; Y144-F219 HydrophobicContact CE2-CB 4.06Å; Y144-F219 HydrophobicContact CE2-CD2 4.14Å; Y144-F219 AromaticContact CG-CD2 3.46Å; Y144-F219 HydrophobicContact CG-CD2 3.46Å; Y144-F219 VanDerWaalsContact CG-CD2 3.46Å; Y144-F219 HydrophobicContact CG-CE2 4.08Å; Y144-F219 HydrophobicContact CG-CG 4.39Å
145L95Very high90.8Very high4 Ų426.5 Ų26.52%0.02113%0.126CC..EExtended strand (participates in β ladder)trans-130.1161.6-178.168.883.6000112.3I147 I152 R153 V176 L179 I218L145-I147 HydrophobicContact CD1-CG1 3.92Å; L145-I152 HydrophobicContact CB-CG2 4.43Å; L145-I152 HydrophobicContact CD1-CG2 4.41Å; L145-I152 HydrophobicContact CD2-CG2 4.46Å; L145-R153 WeakPolarHBondContact CA-O 3.38Å; L145-R153 WeakPolarHBondContact CB-O 3.23Å; L145-V176 HydrophobicContact CD2-CG2 3.84Å; L145-L179 HydrophobicContact CB-CD1 4.05Å; L145-L179 HydrophobicContact CD2-CD1 4.31Å; L145-L179 HydrophobicContact CD2-CD2 3.91Å; L145-I218 HydrophobicContact CD1-CB 3.81Å; L145-I218 HydrophobicContact CD1-CD1 4.16Å; L145-I218 HydrophobicContact CD1-CG1 4.02Å; L145-I218 HydrophobicContact CG-CB 4.05Å; L145-I218 PolarHBondContact N-O 3.36Å; L145-I218 VanDerWaalsContact N-O 3.07Å; L145-I218 PolarHBondContact O-N 3.23Å
146E92.5Very high91.6Very high2 Ų219.9 Ų19.91%0.0099%0.09CC..EExtended strand (participates in β ladder)trans-125.4136.6173.7-176.1169.5-125.500109.9R153 L155 R201 H211 S215 H216E146-R153 PolarHBondContact N-O 3.45Å; E146-R153 PolarHBondContact O-N 2.8Å; E146-L155 HydrophobicContact CB-CD1 4.09Å; E146-L155 HydrophobicContact CB-CD2 3.9Å; E146-L155 HydrophobicContact CB-CG 3.99Å; E146-R201 VanDerWaalsContact OE1-CG 3.3Å; E146-R201 WeakPolarHBondContact OE1-CG 3.23Å; E146-R201 IonicContact OE1-NE 3.2Å; E146-R201 PolarHBondContact OE1-NE 3.03Å; E146-H211 IonicContact OE1-CE1 3.23Å; E146-H211 PolarHBondContact OE1-CE1 3.07Å; E146-H211 VanDerWaalsContact OE1-CE1 3.28Å; E146-H211 IonicContact OE1-ND1 3.11Å; E146-H211 PolarHBondContact OE1-ND1 3.03Å; E146-H211 IonicContact OE2-CE1 2.72Å; E146-S215 WeakPolarHBondContact OE1-CB 3.42Å; E146-S215 PolarHBondContact OE1-OG 2.99Å; E146-H216 CarbonylContact C-O 3.58Å; E146-H216 WeakPolarHBondContact CA-O 3.35Å
147I91.3Very high91.9Very high2 Ų220 Ų201%0.019%0.094CC..EExtended strand (participates in β ladder)trans-105.6117.5167.5-47.6178.8000107.3L145 E151 I152 S215 H216 I218 K296 L297 L300L145-I147 HydrophobicContact CD1-CG1 3.92Å; I147-E151 WeakPolarHBondContact CA-O 3.43Å; I147-I152 HydrophobicContact CG1-CG1 4.47Å; I147-S215 WeakPolarHBondContact O-CA 3.4Å; I147-H216 HydrophobicContact CB-CB 4.29Å; I147-H216 PolarHBondContact N-O 2.89Å; I147-H216 PolarHBondContact O-N 3.11Å; I147-I218 HydrophobicContact CD1-CD1 4.11Å; I147-K296 HydrophobicContact CG2-CB 4.42Å; I147-L297 HydrophobicContact CD1-CB 4.04Å; I147-L297 HydrophobicContact CD1-CD1 4.02Å; I147-L300 HydrophobicContact CD1-CD1 3.78Å
148Y86.7Confident91.9Very high36 Ų3627.2 Ų27.214%0.14112%0.124CC..EExtended strand (participates in β ladder)trans-139.6128.7179.1175.5-111.8000109E150 E151 H211 R214 E264Y148-E150 VanDerWaalsContact C-N 3.26Å; Y148-E150 PolarHBondContact O-N 2.89Å; Y148-E151 PolarHBondContact N-O 3.46Å; Y148-E151 PolarHBondContact O-N 3.05Å; Y148-H211 AromaticContact CD1-NE2 3.86Å; Y148-H211 AromaticContact CD2-CE1 3.85Å; Y148-H211 AromaticContact CD2-NE2 3.63Å; Y148-H211 AromaticContact CE1-NE2 3.84Å; Y148-H211 AromaticContact CE2-NE2 3.63Å; Y148-H211 AromaticContact CG-CE1 3.94Å; Y148-H211 AromaticContact CG-NE2 3.74Å; Y148-H211 AromaticContact CZ-NE2 3.72Å; Y148-R214 WeakPolarHBondContact CD2-O 3.31Å; Y148-R214 HydrophobicContact CE2-CB 4.5Å; Y148-E264 HydrophobicContact CE2-CG 4.15Å; Y148-E264 PolarHBondContact OH-OE1 3.03Å
149Q81.6Confident91.7Very high58 Ų5831.1 Ų31.127%0.27115%0.145SC..THydrogen-bonded Turntrans54.633.9-177.4-61-169.517.200115.6E151 E264 K267Q149-E151 PolarHBondContact O-N 3.04Å; Q149-E264 HydrophobicContact CG-CG 4.48Å; Q149-K267 HydrophobicContact CB-CD 3.65Å; Q149-K267 HydrophobicContact CG-CD 4.15Å; Q149-K267 PolarHBondContact O-NZ 3.24Å
150E87.4Confident91.2Very high36 Ų3632.9 Ų32.917%0.16815%0.154CC..THydrogen-bonded Turntrans62.716.6-171.3-67.4-60.4103.800115.5Y148 L270 S271 S295 K296Y148-E150 VanDerWaalsContact C-N 3.26Å; Y148-E150 PolarHBondContact O-N 2.89Å; E150-L270 HydrophobicContact CG-CD2 4.19Å; E150-S271 WeakPolarHBondContact OE1-CB 3.33Å; E150-S295 WeakPolarHBondContact OE2-CA 3.41Å; E150-S295 WeakPolarHBondContact OE2-CB 3.3Å; E150-K296 WeakPolarHBondContact O-CG 3.33Å; E150-K296 WeakPolarHBondContact OE2-CG 3.4Å; E150-K296 PolarHBondContact OE2-N 2.66Å
151E89Confident90.5Very high76 Ų7637.1 Ų37.136%0.35518%0.183SC..EExtended strand (participates in β ladder)trans-106.6137.9171.2-55.8-172122.300110.5I147 Y148 Q149 R163I147-E151 WeakPolarHBondContact CA-O 3.43Å; Y148-E151 PolarHBondContact N-O 3.46Å; Y148-E151 PolarHBondContact O-N 3.05Å; Q149-E151 PolarHBondContact O-N 3.04Å; E151-R163 HydrophobicContact CB-CG 4.49Å; E151-R163 VanDerWaalsContact CD-NE 3.32Å; E151-R163 IonicContact OE1-NE 2.69Å; E151-R163 IonicContact OE2-CZ 2.75Å; E151-R163 IonicContact OE2-NE 2.68Å; E151-R163 PolarHBondContact OE2-NE 2.85Å; E151-R163 IonicContact OE2-NH2 3.96Å; E151-R163 PolarHBondContact OE2-NH2 3.44Å
152I92.4Very high90.1Very high2 Ų239.2 Ų39.21%0.0119%0.193CC..EExtended strand (participates in β ladder)trans-94130176.2-57.2176.9000109.1L145 I147 R163 L164 L166 V176 K296 L300L145-I152 HydrophobicContact CB-CG2 4.43Å; L145-I152 HydrophobicContact CD1-CG2 4.41Å; L145-I152 HydrophobicContact CD2-CG2 4.46Å; I147-I152 HydrophobicContact CG1-CG1 4.47Å; I152-R163 WeakPolarHBondContact O-CA 3.41Å; I152-L164 HydrophobicContact CB-CB 4.3Å; I152-L164 HydrophobicContact CG2-CB 4.16Å; I152-L164 PolarHBondContact O-N 2.81Å; I152-L166 HydrophobicContact CD1-CD1 4.18Å; I152-L166 HydrophobicContact CD1-CD2 3.43Å; I152-L166 VanDerWaalsContact CD1-CD2 3.43Å; I152-L166 HydrophobicContact CD1-CG 3.56Å; I152-V176 HydrophobicContact CD1-CG2 4.23Å; I152-V176 HydrophobicContact CG2-CG1 4.05Å; I152-V176 HydrophobicContact CG2-CG2 4.46Å; I152-K296 HydrophobicContact CD1-CB 4.39Å; I152-K296 HydrophobicContact CG1-CB 4.44Å; I152-L300 HydrophobicContact CD1-CD1 4.03Å
153R92Very high89.7Confident33 Ų3344 Ų4413%0.12521%0.211CC..EExtended strand (participates in β ladder)trans-123.6134.8176.2178.3174.4163.7-162.5-6.1109.9L145 E146 Q160 N200L145-R153 WeakPolarHBondContact CA-O 3.38Å; L145-R153 WeakPolarHBondContact CB-O 3.23Å; E146-R153 PolarHBondContact N-O 3.45Å; E146-R153 PolarHBondContact O-N 2.8Å; R153-Q160 PolarHBondContact NE-O 2.77Å; R153-N200 PolarHBondContact NH2-O 3.32Å; R153-N200 VanDerWaalsContact NH2-O 3.14Å
154D94.9Very high89.5Confident8 Ų844.3 Ų44.34%0.04321%0.212CC..EExtended strand (participates in β ladder)trans-82.1119.4173.2-175.9-25.6000109.6L156 S157 Q160 L164 L179 S180D154-L156 VanDerWaalsContact C-N 3.3Å; D154-L156 WeakPolarHBondContact OD1-CA 3.45Å; D154-L156 PolarHBondContact OD1-N 3.29Å; D154-S157 PolarHBondContact OD1-N 3.4Å; D154-Q160 PolarHBondContact O-NE2 3.42Å; D154-Q160 PolarHBondContact O-OE1 3.14Å; D154-L164 HydrophobicContact CB-CD1 3.89Å; D154-L179 HydrophobicContact CB-CD1 4.17Å; D154-S180 VanDerWaalsContact CG-OG 3.24Å; D154-S180 PolarHBondContact OD1-OG 3.38Å; D154-S180 VanDerWaalsContact OD1-OG 3.07Å; D154-S180 WeakPolarHBondContact OD2-CB 3.46Å; D154-S180 PolarHBondContact OD2-N 2.86Å; D154-S180 PolarHBondContact OD2-OG 2.87Å
155L93.3Very high89.2Confident0 Ų047 Ų470%023%0.225CC..SBendtrans-79.8-11.1-179.4-66178.2000113Y144 E146 G197 N200 R201Y144-L155 HydrophobicContact CD1-CB 4.34Å; Y144-L155 HydrophobicContact CD1-CD1 4.02Å; Y144-L155 HydrophobicContact CD2-CD1 3.82Å; Y144-L155 HydrophobicContact CE1-CD1 3.98Å; Y144-L155 HydrophobicContact CE2-CD1 3.81Å; Y144-L155 HydrophobicContact CG-CB 4.26Å; Y144-L155 HydrophobicContact CG-CD1 3.93Å; Y144-L155 WeakPolarHBondContact O-CB 3.46Å; Y144-L155 PolarHBondContact O-N 2.84Å; E146-L155 HydrophobicContact CB-CD1 4.09Å; E146-L155 HydrophobicContact CB-CD2 3.9Å; E146-L155 HydrophobicContact CB-CG 3.99Å; L155-G197 WeakPolarHBondContact O-CA 3.48Å; L155-N200 WeakPolarHBondContact O-CB 3.42Å; L155-N200 PolarHBondContact O-ND2 2.68Å; L155-R201 HydrophobicContact CD1-CB 4.33Å; L155-R201 HydrophobicContact CD2-CB 4.12Å
156L94.3Very high89.1Confident13 Ų1347.7 Ų47.77%0.06823%0.228CC..SBendtrans-106.1-15.3-178.8-49.1178.5000112.9Y144 D154 F182 V193Y144-L156 HydrophobicContact CD1-CD2 4.48Å; D154-L156 VanDerWaalsContact C-N 3.3Å; D154-L156 WeakPolarHBondContact OD1-CA 3.45Å; D154-L156 PolarHBondContact OD1-N 3.29Å; L156-F182 HydrophobicContact CB-CD2 4.09Å; L156-F182 HydrophobicContact CB-CE2 3.55Å; L156-F182 HydrophobicContact CB-CZ 4.4Å; L156-F182 HydrophobicContact CD1-CD2 3.73Å; L156-F182 HydrophobicContact CD1-CE2 4.09Å; L156-F182 HydrophobicContact CG-CE2 4.45Å; L156-V193 HydrophobicContact CD1-CG1 3.52Å; L156-V193 HydrophobicContact CD2-CG1 3.7Å; L156-V193 WeakPolarHBondContact CD2-O 3.16Å; L156-V193 HydrophobicContact CG-CG1 4.27Å
157S91.4Very high88.9Confident28 Ų2850.5 Ų50.520%0.19624%0.241CC..SBendtrans-58.4147.1171.6175.30000112.4D154 D159 Q160D154-S157 PolarHBondContact OD1-N 3.4Å; S157-D159 WeakPolarHBondContact CB-O 3.38Å; S157-D159 PolarHBondContact OG-N 3.29Å; S157-D159 PolarHBondContact OG-O 2.9Å; S157-Q160 PolarHBondContact O-NE2 3.07Å
158K85.9Confident88.7Confident219 Ų21954.7 Ų54.795%0.95226%0.26SS*.SBendtrans-71.6-35.3168.3-64.3-174.9-178.7-178.10112.1Q160K158-Q160 PolarHBondContact O-N 2.7Å
159D86.1Confident88.4Confident82 Ų8258.8 Ų58.844%0.43928%0.275SS..  trans-88.9105.3172.4-178.41.2000108.8S157 S161 K162S157-D159 WeakPolarHBondContact CB-O 3.38Å; S157-D159 PolarHBondContact OG-N 3.29Å; S157-D159 PolarHBondContact OG-O 2.9Å; D159-S161 VanDerWaalsContact C-N 3.35Å; D159-S161 WeakPolarHBondContact OD1-CA 3.22Å; D159-S161 WeakPolarHBondContact OD1-CB 3.34Å; D159-S161 PolarHBondContact OD1-N 3.43Å; D159-S161 PolarHBondContact OD1-OG 2.93Å; D159-K162 PolarHBondContact OD1-N 3.35Å
160Q80.9Confident88.1Confident38 Ų3862.8 Ų62.818%0.17831%0.307CS..SBendtrans-88.4-2.8178.7-70.8-65.6-49.500112.9R153 D154 S157 K158R153-Q160 PolarHBondContact NE-O 2.77Å; D154-Q160 PolarHBondContact O-NE2 3.42Å; D154-Q160 PolarHBondContact O-OE1 3.14Å; S157-Q160 PolarHBondContact O-NE2 3.07Å; K158-Q160 PolarHBondContact O-N 2.7Å
161S79.8Confident87.3Confident90 Ų9065.9 Ų65.963%0.62932%0.324SS*.SBendtrans-91.5-26.1175.774.30000113.1D159 R163D159-S161 VanDerWaalsContact C-N 3.35Å; D159-S161 WeakPolarHBondContact OD1-CA 3.22Å; D159-S161 WeakPolarHBondContact OD1-CB 3.34Å; D159-S161 PolarHBondContact OD1-N 3.43Å; D159-S161 PolarHBondContact OD1-OG 2.93Å; S161-R163 PolarHBondContact O-N 3.47Å
162K87.1Confident86.4Confident81 Ų8165.1 Ų65.135%0.35233%0.325SS..  trans-57.8127.2176.1-170.9-177.3-180-1680111.1D159 L164 D178D159-K162 PolarHBondContact OD1-N 3.35Å; K162-L164 HydrophobicContact CD-CD2 3.81Å; K162-L164 HydrophobicContact CG-CD2 4.09Å; K162-D178 IonicContact NZ-OD2 2.65Å; K162-D178 PolarHBondContact NZ-OD2 3.31Å
163R88.4Confident85.9Confident99 Ų9966 Ų6637%0.37434%0.335SS..  trans-91.5143.4166.7-56.4-46.3-158.9-170.57.6109.8E151 I152 S161E151-R163 HydrophobicContact CB-CG 4.49Å; E151-R163 VanDerWaalsContact CD-NE 3.32Å; E151-R163 IonicContact OE1-NE 2.69Å; E151-R163 IonicContact OE2-CZ 2.75Å; E151-R163 IonicContact OE2-NE 2.68Å; E151-R163 PolarHBondContact OE2-NE 2.85Å; E151-R163 IonicContact OE2-NH2 3.96Å; E151-R163 PolarHBondContact OE2-NH2 3.44Å; I152-R163 WeakPolarHBondContact O-CA 3.41Å; S161-R163 PolarHBondContact O-N 3.47Å
164L92.8Very high85.7Confident17 Ų1765 Ų659%0.08933%0.332CS..BIsolated β-bridgetrans-109.6147.2179.8-58.9-171.9000112.4I152 D154 K162 V176 D178 L179I152-L164 HydrophobicContact CB-CB 4.3Å; I152-L164 HydrophobicContact CG2-CB 4.16Å; I152-L164 PolarHBondContact O-N 2.81Å; D154-L164 HydrophobicContact CB-CD1 3.89Å; K162-L164 HydrophobicContact CD-CD2 3.81Å; K162-L164 HydrophobicContact CG-CD2 4.09Å; L164-V176 HydrophobicContact CB-CG1 3.51Å; L164-V176 HydrophobicContact CD1-CG1 3.63Å; L164-V176 HydrophobicContact CG-CG1 4.23Å; L164-D178 HydrophobicContact CD2-CB 4.29Å; L164-L179 HydrophobicContact CD1-CB 4.13Å; L164-L179 HydrophobicContact CD1-CD1 4.05Å
165E90.8Very high85.5Confident63 Ų6367.4 Ų67.429%0.29434%0.341SS..  trans-95.7147.9-179.2-67.8150.4-159.900111.1K167 K177E165-K167 WeakPolarHBondContact OE2-CE 3.42Å; E165-K167 IonicContact OE2-NZ 3.76Å; E165-K177 PolarHBondContact O-N 3.32Å; E165-K177 IonicContact OE2-NZ 3.59Å; E165-K177 PolarHBondContact OE2-NZ 2.99Å
166L91.6Very high85.5Confident18 Ų1868.1 Ų68.19%0.09435%0.345CS..EExtended strand (participates in β ladder)trans-89.1130166-69.3-179.1000109.9I152 V174 V176 K296 R299 L300I152-L166 HydrophobicContact CD1-CD1 4.18Å; I152-L166 HydrophobicContact CD1-CD2 3.43Å; I152-L166 VanDerWaalsContact CD1-CD2 3.43Å; I152-L166 HydrophobicContact CD1-CG 3.56Å; L166-V174 HydrophobicContact CD1-CG1 4.46Å; L166-V174 HydrophobicContact CD2-CG1 4.25Å; L166-V176 HydrophobicContact CD2-CG2 3.78Å; L166-K296 HydrophobicContact CD1-CB 3.99Å; L166-K296 HydrophobicContact CD1-CD 3.85Å; L166-K296 HydrophobicContact CD1-CG 4.48Å; L166-K296 HydrophobicContact CG-CD 4.36Å; L166-R299 HydrophobicContact CD1-CB 3.75Å; L166-L300 HydrophobicContact CD1-CG 4.31Å; L166-L300 HydrophobicContact CD2-CD1 4.07Å; L166-L300 HydrophobicContact CD2-CD2 3.66Å; L166-L300 HydrophobicContact CD2-CG 3.7Å
167K89.8Confident85.3Confident61 Ų6170.7 Ų70.727%0.26536%0.356SS..EExtended strand (participates in β ladder)trans-124162.6169.5-58.6-154.3179.6-115.50109.6E165 Y175 K177 E602E165-K167 WeakPolarHBondContact OE2-CE 3.42Å; E165-K167 IonicContact OE2-NZ 3.76Å; K167-Y175 HydrophobicContact CB-CE1 3.94Å; K167-Y175 PolarHBondContact N-O 3.45Å; K167-Y175 WeakPolarHBondContact O-CD1 3.31Å; K167-Y175 PolarHBondContact O-N 3.09Å; K167-Y175 VanDerWaalsContact O-O 3.06Å; K167-K177 HydrophobicContact CD-CD 3.93Å; K167-K177 HydrophobicContact CG-CB 4.29Å; K167-E602 IonicContact NZ-OE1 2.72Å; K167-E602 PolarHBondContact NZ-OE1 2.72Å
168E85.6Confident85.3Confident90 Ų9074.1 Ų74.142%0.42137%0.372SS..EExtended strand (participates in β ladder)trans-133.8133-172-170.2170.5166.600107.9G173 V174 R299E168-G173 WeakPolarHBondContact CA-O 3.45Å; E168-V174 HydrophobicContact CB-CG2 4.4Å; E168-V174 HydrophobicContact CG-CG2 3.93Å; E168-R299 IonicContact OE2-NH2 3.49Å; E168-R299 PolarHBondContact OE2-NH2 2.92Å
169R81.6Confident85.7Confident122 Ų12265.7 Ų65.746%0.4634%0.337SS..EExtended strand (participates in β ladder)trans-126.4148.6173.1-73.8168.8-176.7-155.2-1.2110.1D171 G173 Y175R169-D171 WeakPolarHBondContact CB-OD1 3.5Å; R169-D171 PolarHBondContact O-N 3.02Å; R169-G173 PolarHBondContact N-O 3.15Å; R169-G173 WeakPolarHBondContact O-CA 3.47Å; R169-G173 PolarHBondContact O-N 2.84Å; R169-Y175 HydrophobicContact CG-CE1 3.83Å; R169-Y175 PolarHBondContact NE-OH 3.48Å
170P75.4Confident86.1Confident143 Ų14363.2 Ų63.293%0.92933%0.326SS*.THydrogen-bonded Turntrans-63-25.3178.3-2334.6000114.8
171D69.9Low86.7Confident100 Ų10064 Ų6454%0.53534%0.336SS..THydrogen-bonded Turntrans-84.4-51.4179.741.446.4000112.7R169R169-D171 WeakPolarHBondContact CB-OD1 3.5Å; R169-D171 PolarHBondContact O-N 3.02Å
172T70.4Confident87.4Confident60 Ų6064.1 Ų64.137%0.36833%0.325SS..THydrogen-bonded Turntrans-94.2-17-167.8-46.50000112.8
173G81.6Confident87.7Confident21 Ų2162.4 Ų62.422%0.21632%0.321CS..EExtended strand (participates in β ladder)trans75.8-148.5-168.700000112.6E168 R169E168-G173 WeakPolarHBondContact CA-O 3.45Å; R169-G173 PolarHBondContact N-O 3.15Å; R169-G173 WeakPolarHBondContact O-CA 3.47Å; R169-G173 PolarHBondContact O-N 2.84Å
174V87.9Confident87.9Confident13 Ų1357.8 Ų57.88%0.07930%0.304CS..EExtended strand (participates in β ladder)trans-82.9130.1179.6-179.70000110.3L166 E168 R299L166-V174 HydrophobicContact CD1-CG1 4.46Å; L166-V174 HydrophobicContact CD2-CG1 4.25Å; E168-V174 HydrophobicContact CB-CG2 4.4Å; E168-V174 HydrophobicContact CG-CG2 3.93Å; V174-R299 HydrophobicContact CG1-CB 4.34Å
175Y90.2Very high87.7Confident58 Ų5860.3 Ų60.323%0.22732%0.315CS..EExtended strand (participates in β ladder)trans-141.5159.9178.272.9-77.2000112.1K167 R169K167-Y175 HydrophobicContact CB-CE1 3.94Å; K167-Y175 PolarHBondContact N-O 3.45Å; K167-Y175 WeakPolarHBondContact O-CD1 3.31Å; K167-Y175 PolarHBondContact O-N 3.09Å; K167-Y175 VanDerWaalsContact O-O 3.06Å; R169-Y175 HydrophobicContact CG-CE1 3.83Å; R169-Y175 PolarHBondContact NE-OH 3.48Å
176V93.4Very high87.7Confident14 Ų1459.4 Ų59.49%0.08532%0.315CS..EExtended strand (participates in β ladder)trans-89.2122.8174.5-172.70000108.8L145 I152 L164 L166 L179 L300L145-V176 HydrophobicContact CD2-CG2 3.84Å; I152-V176 HydrophobicContact CD1-CG2 4.23Å; I152-V176 HydrophobicContact CG2-CG1 4.05Å; I152-V176 HydrophobicContact CG2-CG2 4.46Å; L164-V176 HydrophobicContact CB-CG1 3.51Å; L164-V176 HydrophobicContact CD1-CG1 3.63Å; L164-V176 HydrophobicContact CG-CG1 4.23Å; L166-V176 HydrophobicContact CD2-CG2 3.78Å; V176-L179 HydrophobicContact CB-CB 3.88Å; V176-L179 HydrophobicContact CB-CD2 4.12Å; V176-L179 HydrophobicContact CG1-CB 3.96Å; V176-L179 HydrophobicContact CG2-CD2 4.35Å; V176-L300 HydrophobicContact CG2-CD1 4.39Å; V176-L300 HydrophobicContact CG2-CD2 3.82Å
177K91.4Very high87.7Confident68 Ų6860.1 Ų60.130%0.29632%0.32SS..THydrogen-bonded Turntrans-71.4141.4175.7173.8-177.4151.5-146.10110.3E165 K167 L179E165-K177 PolarHBondContact O-N 3.32Å; E165-K177 IonicContact OE2-NZ 3.59Å; E165-K177 PolarHBondContact OE2-NZ 2.99Å; K167-K177 HydrophobicContact CD-CD 3.93Å; K167-K177 HydrophobicContact CG-CB 4.29Å; K177-L179 PolarHBondContact O-N 2.82Å; K177-L179 VanDerWaalsContact O-N 3.15Å
178D91.3Very high87.8Confident99 Ų9965.3 Ų65.353%0.52934%0.343SS..THydrogen-bonded Turntrans56.220.1-179.1-48.9-17.3000115.6K162 L164 S180K162-D178 IonicContact NZ-OD2 2.65Å; K162-D178 PolarHBondContact NZ-OD2 3.31Å; L164-D178 HydrophobicContact CD2-CB 4.29Å; D178-S180 PolarHBondContact O-N 3.4Å
179L93.6Very high88.2Confident42 Ų4264.6 Ų64.622%0.2234%0.339CS..  trans-67.4125.4173.2179.466.5000109.9L145 D154 L164 V176 K177L145-L179 HydrophobicContact CB-CD1 4.05Å; L145-L179 HydrophobicContact CD2-CD1 4.31Å; L145-L179 HydrophobicContact CD2-CD2 3.91Å; D154-L179 HydrophobicContact CB-CD1 4.17Å; L164-L179 HydrophobicContact CD1-CB 4.13Å; L164-L179 HydrophobicContact CD1-CD1 4.05Å; V176-L179 HydrophobicContact CB-CB 3.88Å; V176-L179 HydrophobicContact CB-CD2 4.12Å; V176-L179 HydrophobicContact CG1-CB 3.96Å; V176-L179 HydrophobicContact CG2-CD2 4.35Å; K177-L179 PolarHBondContact O-N 2.82Å; K177-L179 VanDerWaalsContact O-N 3.15Å
180S93.9Very high88.8Confident30 Ų3058.9 Ų58.921%0.2132%0.318CS..  trans-68.4146.3178.569.10000111.7S143 D154 D178S143-S180 VanDerWaalsContact CB-O 3.32Å; S143-S180 WeakPolarHBondContact CB-O 3.39Å; S143-S180 PolarHBondContact OG-O 2.89Å; D154-S180 VanDerWaalsContact CG-OG 3.24Å; D154-S180 PolarHBondContact OD1-OG 3.38Å; D154-S180 VanDerWaalsContact OD1-OG 3.07Å; D154-S180 WeakPolarHBondContact OD2-CB 3.46Å; D154-S180 PolarHBondContact OD2-N 2.86Å; D154-S180 PolarHBondContact OD2-OG 2.87Å; D178-S180 PolarHBondContact O-N 3.4Å
181S93.2Very high89.7Confident54 Ų5454.4 Ų54.438%0.37828%0.284SS..  trans-141.1125.9-178.7-154.30000109.4A142 S143A142-S181 WeakPolarHBondContact O-CA 3.33Å; S143-S181 WeakPolarHBondContact OG-CA 3.43Å; S143-S181 VanDerWaalsContact OG-CB 3.27Å; S143-S181 WeakPolarHBondContact OG-CB 3.28Å; S143-S181 PolarHBondContact OG-OG 3.49Å
182F94.9Very high90.8Very high94 Ų9455.5 Ų55.541%0.41229%0.286SS..EExtended strand (participates in β ladder)trans-108.9125.5-174.4-72.2-100.7000109.5R141 A142 L156 T184 V193R141-F182 CarbonylContact C-O 3.55Å; R141-F182 VanDerWaalsContact CA-O 3.28Å; R141-F182 WeakPolarHBondContact CA-O 3.48Å; A142-F182 PolarHBondContact N-O 2.88Å; A142-F182 PolarHBondContact O-N 3.45Å; L156-F182 HydrophobicContact CB-CD2 4.09Å; L156-F182 HydrophobicContact CB-CE2 3.55Å; L156-F182 HydrophobicContact CB-CZ 4.4Å; L156-F182 HydrophobicContact CD1-CD2 3.73Å; L156-F182 HydrophobicContact CD1-CE2 4.09Å; L156-F182 HydrophobicContact CG-CE2 4.45Å; F182-T184 PolarHBondContact O-N 3.42Å; F182-V193 HydrophobicContact CB-CG2 4.06Å; F182-V193 HydrophobicContact CG-CG2 4.5Å
183V94.3Very high92Very high44 Ų4453.4 Ų53.427%0.26727%0.273SS..EExtended strand (participates in β ladder)trans-70.8127.1171.6178.60000108.3L139 V140 R141 K466L139-V183 HydrophobicContact CD1-CG1 3.65Å; L139-V183 HydrophobicContact CD1-CG2 4.12Å; V140-V183 WeakPolarHBondContact O-CA 3.42Å; R141-V183 HydrophobicContact CG-CG2 4.13Å; V183-K466 HydrophobicContact CG1-CB 4.27Å
184T93.1Very high92.6Very high2 Ų252.9 Ų52.91%0.01227%0.265CS..  trans-122.9127.6-177.354.10000110.3F127 V140 A142 F182 E189 I190 V193F127-T184 WeakPolarHBondContact CZ-O 3.34Å; V140-T184 PolarHBondContact O-N 3.41Å; A142-T184 HydrophobicContact CB-CG2 4.24Å; F182-T184 PolarHBondContact O-N 3.42Å; T184-E189 HydrophobicContact CG2-CB 4.41Å; T184-I190 HydrophobicContact CG2-CB 3.89Å; T184-I190 HydrophobicContact CG2-CG1 4.23Å; T184-V193 HydrophobicContact CG2-CG2 3.97Å
185K88.8Confident92.8Very high71 Ų7155.5 Ų55.531%0.30928%0.279SS..  trans-103.5-12.6-172.5-52.5173.9-174.6-163.10114E189 S465 L468K185-E189 WeakPolarHBondContact CB-OE2 3.43Å; K185-E189 WeakPolarHBondContact CG-OE2 3.4Å; K185-E189 PolarHBondContact N-OE2 2.9Å; K185-S465 VanDerWaalsContact CD-O 3.24Å; K185-S465 WeakPolarHBondContact CD-O 3.44Å; K185-S465 WeakPolarHBondContact CE-O 3.36Å; K185-S465 PolarHBondContact NZ-O 3.23Å; K185-S465 PolarHBondContact NZ-OG 2.93Å; K185-L468 HydrophobicContact CB-CD2 4.07Å; K185-L468 WeakPolarHBondContact O-CD2 3.38Å
186S89.8Confident92.9Very high43 Ų4354.8 Ų54.830%0.30128%0.281SS..SBendtrans-151.9162.9-179.168.60000111.8K188 E189 I190S186-K188 PolarHBondContact O-N 2.95Å; S186-E189 PolarHBondContact O-N 3.07Å; S186-E189 PolarHBondContact OG-N 3.19Å; S186-I190 PolarHBondContact O-N 3.17Å
187V91.8Very high92.8Very high34 Ų3454.1 Ų54.121%0.20628%0.277CS..Hα-helixtrans-51-42.1173.2-176.80000111.3F123 F127 E189 I190 E191F123-V187 HydrophobicContact CB-CG1 4.25Å; F127-V187 HydrophobicContact CB-CG2 3.73Å; F127-V187 HydrophobicContact CD2-CG2 3.9Å; F127-V187 HydrophobicContact CG-CG2 4.1Å; V187-E189 PolarHBondContact O-N 3.05Å; V187-I190 VanDerWaalsContact O-CG2 3.25Å; V187-I190 WeakPolarHBondContact O-CG2 3.42Å; V187-I190 PolarHBondContact O-N 2.75Å; V187-E191 HydrophobicContact CG1-CG 4.2Å; V187-E191 WeakPolarHBondContact O-CB 3.15Å; V187-E191 VanDerWaalsContact O-CG 3.32Å; V187-E191 WeakPolarHBondContact O-CG 3.46Å; V187-E191 PolarHBondContact O-N 3.35Å
188K91.8Very high92.6Very high169 Ų16951.5 Ų51.574%0.73527%0.266SS*.Hα-helixtrans-64.5-36.3179.8-66-177.2-179.8178.10113.1S186 H192S186-K188 PolarHBondContact O-N 2.95Å; K188-H192 WeakPolarHBondContact O-CB 3.47Å; K188-H192 PolarHBondContact O-N 3.42Å
189E93.9Very high92.4Very high76 Ų7652.7 Ų52.736%0.35527%0.268SS..Hα-helixtrans-70.5-43.5178-73176.5-155.700111.6T184 K185 S186 V187 H192 V193T184-E189 HydrophobicContact CG2-CB 4.41Å; K185-E189 WeakPolarHBondContact CB-OE2 3.43Å; K185-E189 WeakPolarHBondContact CG-OE2 3.4Å; K185-E189 PolarHBondContact N-OE2 2.9Å; S186-E189 PolarHBondContact O-N 3.07Å; S186-E189 PolarHBondContact OG-N 3.19Å; V187-E189 PolarHBondContact O-N 3.05Å; E189-H192 WeakPolarHBondContact O-CB 3.46Å; E189-H192 PolarHBondContact O-N 2.93Å; E189-V193 WeakPolarHBondContact O-CG2 3.48Å; E189-V193 PolarHBondContact O-N 3.45Å
190I95.1Very high92.1Very high1 Ų152.5 Ų52.51%0.00527%0.267CS..Hα-helixtrans-72.5-34.2178-164.2164000112.3F123 F127 A142 T184 S186 V187 H192 V193 M194 F219 I221F123-I190 HydrophobicContact CB-CG2 3.71Å; F123-I190 HydrophobicContact CD1-CD1 3.7Å; F123-I190 HydrophobicContact CD1-CG1 3.97Å; F123-I190 HydrophobicContact CD1-CG2 3.96Å; F123-I190 HydrophobicContact CD2-CG1 4.43Å; F123-I190 HydrophobicContact CD2-CG2 3.6Å; F123-I190 HydrophobicContact CE1-CD1 3.68Å; F123-I190 HydrophobicContact CE1-CG1 3.74Å; F123-I190 HydrophobicContact CE1-CG2 4.46Å; F123-I190 HydrophobicContact CE2-CG1 4.22Å; F123-I190 HydrophobicContact CE2-CG2 4.14Å; F123-I190 HydrophobicContact CG-CD1 4.37Å; F123-I190 HydrophobicContact CG-CG1 4.32Å; F123-I190 HydrophobicContact CG-CG2 3.49Å; F123-I190 VanDerWaalsContact CG-CG2 3.49Å; F123-I190 HydrophobicContact CZ-CD1 4.32Å; F123-I190 HydrophobicContact CZ-CG1 3.86Å; F127-I190 HydrophobicContact CD2-CG2 4.33Å; F127-I190 HydrophobicContact CE2-CB 4.23Å; F127-I190 HydrophobicContact CE2-CD1 4.47Å; F127-I190 HydrophobicContact CE2-CG2 3.66Å; A142-I190 HydrophobicContact CB-CD1 4.03Å; A142-I190 HydrophobicContact CB-CG1 4.02Å; T184-I190 HydrophobicContact CG2-CB 3.89Å; T184-I190 HydrophobicContact CG2-CG1 4.23Å; S186-I190 PolarHBondContact O-N 3.17Å; V187-I190 VanDerWaalsContact O-CG2 3.25Å; V187-I190 WeakPolarHBondContact O-CG2 3.42Å; V187-I190 PolarHBondContact O-N 2.75Å; I190-H192 VanDerWaalsContact C-N 3.29Å; I190-H192 PolarHBondContact O-N 3.35Å; I190-V193 PolarHBondContact O-N 2.87Å; I190-M194 PolarHBondContact O-N 3.02Å; I190-F219 HydrophobicContact CD1-CE1 4.15Å; I190-F219 HydrophobicContact CD1-CZ 4.43Å; I190-F219 HydrophobicContact CG1-CE1 4.14Å; I190-F219 HydrophobicContact CG1-CZ 3.93Å; I190-I221 HydrophobicContact CD1-CD1 4.15Å; I190-I221 HydrophobicContact CD1-CG1 4.36Å; I190-I221 HydrophobicContact CD1-CG2 4.36Å
191E93.3Very high91.7Very high49 Ų4951.9 Ų51.923%0.22926%0.26CS..Hα-helixtrans-60.8-38.4167.9-77.7-177.5162.700110.8R116 F123 V187 M194 N195R116-E191 IonicContact CZ-OE1 2.81Å; R116-E191 IonicContact NH1-OE1 3.25Å; R116-E191 PolarHBondContact NH1-OE1 2.97Å; R116-E191 IonicContact NH2-OE1 3.94Å; F123-E191 HydrophobicContact CD2-CG 3.97Å; F123-E191 HydrophobicContact CE2-CG 4.37Å; V187-E191 HydrophobicContact CG1-CG 4.2Å; V187-E191 WeakPolarHBondContact O-CB 3.15Å; V187-E191 VanDerWaalsContact O-CG 3.32Å; V187-E191 WeakPolarHBondContact O-CG 3.46Å; V187-E191 PolarHBondContact O-N 3.35Å; E191-M194 PolarHBondContact O-N 2.82Å; E191-N195 WeakPolarHBondContact O-CB 3.35Å; E191-N195 PolarHBondContact O-N 2.99Å; E191-N195 PolarHBondContact O-ND2 2.9Å
192H93.6Very high90.5Very high124 Ų12452.3 Ų52.357%0.57426%0.263SS*.Hα-helixtrans-65.3-44.6174.5-175.272.6000112.2K188 E189 I190 M194 N195 V196K188-H192 WeakPolarHBondContact O-CB 3.47Å; K188-H192 PolarHBondContact O-N 3.42Å; E189-H192 WeakPolarHBondContact O-CB 3.46Å; E189-H192 PolarHBondContact O-N 2.93Å; I190-H192 VanDerWaalsContact C-N 3.29Å; I190-H192 PolarHBondContact O-N 3.35Å; H192-M194 VanDerWaalsContact C-N 3.33Å; H192-M194 PolarHBondContact O-N 3.17Å; H192-N195 PolarHBondContact O-N 2.99Å; H192-N195 VanDerWaalsContact O-N 3.17Å; H192-V196 WeakPolarHBondContact O-CG2 3.3Å; H192-V196 PolarHBondContact O-N 3.21Å
193V95.3Very high88.9Confident15 Ų1551.8 Ų51.89%0.09127%0.268CS..Hα-helixtrans-57.1-45.6174.11720000111.3A142 L156 F182 T184 E189 I190 N195 V196 G197 F219A142-V193 HydrophobicContact CB-CG1 3.99Å; L156-V193 HydrophobicContact CD1-CG1 3.52Å; L156-V193 HydrophobicContact CD2-CG1 3.7Å; L156-V193 WeakPolarHBondContact CD2-O 3.16Å; L156-V193 HydrophobicContact CG-CG1 4.27Å; F182-V193 HydrophobicContact CB-CG2 4.06Å; F182-V193 HydrophobicContact CG-CG2 4.5Å; T184-V193 HydrophobicContact CG2-CG2 3.97Å; E189-V193 WeakPolarHBondContact O-CG2 3.48Å; E189-V193 PolarHBondContact O-N 3.45Å; I190-V193 PolarHBondContact O-N 2.87Å; V193-N195 PolarHBondContact O-N 3.5Å; V193-V196 PolarHBondContact O-N 2.93Å; V193-G197 PolarHBondContact O-N 2.95Å; V193-G197 VanDerWaalsContact O-N 3.08Å; V193-F219 HydrophobicContact CG1-CE2 4.35Å; V193-F219 HydrophobicContact CG1-CZ 4.37Å
194M93.7Very high87Confident11 Ų1150.6 Ų50.65%0.05426%0.264CS..Hα-helixtrans-61.3-43.7175.4-172.4-174.2-175.900112.2E107 I119 F123 I190 E191 H192 G197 N198 F219E107-M194 HydrophobicContact CB-CE 3.82Å; E107-M194 HydrophobicContact CG-CE 3.57Å; I119-M194 HydrophobicContact CB-CE 4.05Å; I119-M194 HydrophobicContact CB-SD 4.46Å; I119-M194 HydrophobicContact CD1-CE 3.95Å; I119-M194 HydrophobicContact CG2-CE 3.68Å; I119-M194 HydrophobicContact CG2-SD 3.58Å; I119-M194 VanDerWaalsContact CG2-SD 3.58Å; F123-M194 HydrophobicContact CE2-CB 4.2Å; F123-M194 HydrophobicContact CE2-SD 3.84Å; F123-M194 HydrophobicContact CZ-CB 4.27Å; F123-M194 HydrophobicContact CZ-SD 4.04Å; I190-M194 PolarHBondContact O-N 3.02Å; E191-M194 PolarHBondContact O-N 2.82Å; H192-M194 VanDerWaalsContact C-N 3.33Å; H192-M194 PolarHBondContact O-N 3.17Å; M194-G197 PolarHBondContact O-N 3.49Å; M194-N198 WeakPolarHBondContact O-CB 3.3Å; M194-N198 PolarHBondContact O-N 2.83Å; M194-F219 HydrophobicContact CB-CE2 3.89Å; M194-F219 HydrophobicContact CB-CZ 4.37Å; M194-F219 HydrophobicContact CG-CE2 4.25Å
195N92.1Very high85.2Confident67 Ų6751.8 Ų51.836%0.35827%0.274SS..Hα-helixtrans-63.6-42.1178.5-79.2-54.6000112.7R110 E191 H192 V193 N198 Q199R110-N195 PolarHBondContact NH1-OD1 3.21Å; E191-N195 WeakPolarHBondContact O-CB 3.35Å; E191-N195 PolarHBondContact O-N 2.99Å; E191-N195 PolarHBondContact O-ND2 2.9Å; H192-N195 PolarHBondContact O-N 2.99Å; H192-N195 VanDerWaalsContact O-N 3.17Å; V193-N195 PolarHBondContact O-N 3.5Å; N195-N198 PolarHBondContact O-N 2.85Å; N195-Q199 WeakPolarHBondContact O-CB 3.38Å; N195-Q199 PolarHBondContact O-N 2.98Å
196V92.5Very high83.1Confident44 Ų4453.9 Ų53.927%0.26729%0.293SS..Hα-helixtrans-61.5-48.6175.5170.10000110.9H192 V193 N198 Q199 N200H192-V196 WeakPolarHBondContact O-CG2 3.3Å; H192-V196 PolarHBondContact O-N 3.21Å; V193-V196 PolarHBondContact O-N 2.93Å; V196-N198 VanDerWaalsContact C-N 3.34Å; V196-N198 PolarHBondContact O-N 3.24Å; V196-Q199 WeakPolarHBondContact O-CB 3.3Å; V196-Q199 PolarHBondContact O-N 3.39Å; V196-N200 PolarHBondContact O-N 2.75Å
197G91.3Very high80.9Confident0 Ų058.6 Ų58.60%032%0.315CS..Hα-helixtrans-63.5-39.2178.400000113.3L155 V193 M194 Q199 N200 R201L155-G197 WeakPolarHBondContact O-CA 3.48Å; V193-G197 PolarHBondContact O-N 2.95Å; V193-G197 VanDerWaalsContact O-N 3.08Å; M194-G197 PolarHBondContact O-N 3.49Å; G197-Q199 PolarHBondContact O-N 2.81Å; G197-N200 PolarHBondContact O-N 3.37Å; G197-R201 WeakPolarHBondContact O-CB 3.25Å; G197-R201 PolarHBondContact O-N 3.03Å
198N88.3Confident78.4Confident12 Ų1262.2 Ų62.26%0.06433%0.331CS..Hα-helixtrans-66.7-34.4174-85.8-21.8000113.3E107 R110 Y144 M194 N195 V196 R201 S202E107-N198 VanDerWaalsContact CD-ND2 3.28Å; E107-N198 PolarHBondContact OE1-ND2 2.62Å; E107-N198 PolarHBondContact OE2-ND2 2.79Å; R110-N198 PolarHBondContact NH2-ND2 3.49Å; R110-N198 VanDerWaalsContact NH2-ND2 3.11Å; Y144-N198 PolarHBondContact OH-OD1 2.72Å; M194-N198 WeakPolarHBondContact O-CB 3.3Å; M194-N198 PolarHBondContact O-N 2.83Å; N195-N198 PolarHBondContact O-N 2.85Å; V196-N198 VanDerWaalsContact C-N 3.34Å; V196-N198 PolarHBondContact O-N 3.24Å; N198-R201 PolarHBondContact O-N 2.8Å; N198-S202 WeakPolarHBondContact O-CB 3.14Å; N198-S202 PolarHBondContact O-N 3.35Å; N198-S202 PolarHBondContact O-OG 2.75Å
199Q87.4Confident76Confident125 Ų12558.1 Ų58.158%0.58432%0.317SS*.Hα-helixtrans-63.5-47.7172.2-174.3175.1-0.900110.2N195 V196 G197 R201 S202 V203N195-Q199 WeakPolarHBondContact O-CB 3.38Å; N195-Q199 PolarHBondContact O-N 2.98Å; V196-Q199 WeakPolarHBondContact O-CB 3.3Å; V196-Q199 PolarHBondContact O-N 3.39Å; G197-Q199 PolarHBondContact O-N 2.81Å; Q199-R201 VanDerWaalsContact C-N 3.33Å; Q199-R201 PolarHBondContact O-N 2.91Å; Q199-S202 PolarHBondContact O-N 3.05Å; Q199-S202 VanDerWaalsContact O-N 3.07Å; Q199-S202 PolarHBondContact O-OG 2.87Å; Q199-V203 WeakPolarHBondContact O-CG2 3.43Å; Q199-V203 PolarHBondContact O-N 3.04Å
200N87.3Confident74.1Confident37 Ų3761.5 Ų61.520%0.19833%0.333CS..Hα-helixtrans-63.3-35.3177.5-72.8-22.2000113.2R153 L155 V196 G197R153-N200 PolarHBondContact NH2-O 3.32Å; R153-N200 VanDerWaalsContact NH2-O 3.14Å; L155-N200 WeakPolarHBondContact O-CB 3.42Å; L155-N200 PolarHBondContact O-ND2 2.68Å; V196-N200 PolarHBondContact O-N 2.75Å; G197-N200 PolarHBondContact O-N 3.37Å
201R83.8Confident72.3Confident18 Ų1862.2 Ų62.27%0.06834%0.336CS..Hα-helixtrans-62.1-45169.7-162.9177.8-174.7-157.3-1.5111.3E146 L155 G197 N198 Q199 G204 A205 S212 S215 A217 D245E146-R201 VanDerWaalsContact OE1-CG 3.3Å; E146-R201 WeakPolarHBondContact OE1-CG 3.23Å; E146-R201 IonicContact OE1-NE 3.2Å; E146-R201 PolarHBondContact OE1-NE 3.03Å; L155-R201 HydrophobicContact CD1-CB 4.33Å; L155-R201 HydrophobicContact CD2-CB 4.12Å; G197-R201 WeakPolarHBondContact O-CB 3.25Å; G197-R201 PolarHBondContact O-N 3.03Å; N198-R201 PolarHBondContact O-N 2.8Å; Q199-R201 VanDerWaalsContact C-N 3.33Å; Q199-R201 PolarHBondContact O-N 2.91Å; R201-G204 PolarHBondContact O-N 3.46Å; R201-A205 PolarHBondContact O-N 3.22Å; R201-S212 PolarHBondContact NH2-O 2.87Å; R201-S215 PolarHBondContact NH2-O 3.22Å; R201-S215 PolarHBondContact NH2-OG 3.43Å; R201-A217 VanDerWaalsContact CZ-CB 3.47Å; R201-D245 IonicContact NH1-OD2 3.35Å; R201-D245 PolarHBondContact NH1-OD2 2.7Å
202S69Low70.9Confident62 Ų6262.6 Ų62.643%0.43434%0.344SS..Hα-helixtrans-68.8-34.6-178.973.50000114.5N198 Q199 G204 A205 T206N198-S202 WeakPolarHBondContact O-CB 3.14Å; N198-S202 PolarHBondContact O-N 3.35Å; N198-S202 PolarHBondContact O-OG 2.75Å; Q199-S202 PolarHBondContact O-N 3.05Å; Q199-S202 VanDerWaalsContact O-N 3.07Å; Q199-S202 PolarHBondContact O-OG 2.87Å; S202-G204 PolarHBondContact O-N 3.4Å; S202-A205 WeakPolarHBondContact O-CB 3.34Å; S202-A205 PolarHBondContact O-N 2.86Å; S202-T206 PolarHBondContact O-N 3.11Å; S202-T206 VanDerWaalsContact O-N 3.17Å
203V61.3Low69.6Low84 Ų8457.5 Ų57.551%0.50932%0.322SS..Hα-helixtrans-65-30.4175.1172.80000111.5Q199 T206Q199-V203 WeakPolarHBondContact O-CG2 3.43Å; Q199-V203 PolarHBondContact O-N 3.04Å; V203-T206 PolarHBondContact O-OG1 3.39Å
204G54.9Low68.7Low19 Ų1959.1 Ų59.120%0.19633%0.327CS..Hα-helixtrans-63.7-42.1168.400000112.7R201 S202 T206 N207R201-G204 PolarHBondContact O-N 3.46Å; S202-G204 PolarHBondContact O-N 3.4Å; G204-T206 PolarHBondContact O-N 3.02Å; G204-N207 PolarHBondContact O-N 3.25Å
205A53.9Low68.2Low26 Ų2658.7 Ų58.722%0.21533%0.325CS..Hα-helixtrans-65.4-39.2-177.800000113.7R201 S202 N207 M208 N209 H211R201-A205 PolarHBondContact O-N 3.22Å; S202-A205 WeakPolarHBondContact O-CB 3.34Å; S202-A205 PolarHBondContact O-N 2.86Å; A205-N207 PolarHBondContact O-N 2.94Å; A205-N207 VanDerWaalsContact O-N 3.12Å; A205-M208 PolarHBondContact O-N 3.23Å; A205-N209 CarbonylContact O-C 3.57Å; A205-N209 PolarHBondContact O-N 2.97Å; A205-H211 HydrophobicContact CB-CB 3.57Å
206T45.2Very low68.2Low116 Ų11655.7 Ų55.771%0.71231%0.309SS*.THydrogen-bonded Turntrans-64.1-16.8-177.7420000114.5S202 V203 G204S202-T206 PolarHBondContact O-N 3.11Å; S202-T206 VanDerWaalsContact O-N 3.17Å; V203-T206 PolarHBondContact O-OG1 3.39Å; G204-T206 PolarHBondContact O-N 3.02Å
207N43.1Very low68.2Low142 Ų14253.6 Ų53.676%0.75930%0.296SS*.THydrogen-bonded Turntrans-87-22.1-178-99.40.3000115.3G204 A205G204-N207 PolarHBondContact O-N 3.25Å; A205-N207 PolarHBondContact O-N 2.94Å; A205-N207 VanDerWaalsContact O-N 3.12Å
208M40.4Very low68.5Low110 Ų11053.9 Ų53.954%0.54230%0.297SS..THydrogen-bonded Turntrans-147-20.2-177.5-75.2-163.794.100119.2A205 R261A205-M208 PolarHBondContact O-N 3.23Å; M208-R261 PolarHBondContact O-NH2 3.28Å; M208-R261 VanDerWaalsContact O-NH2 3.08Å
209N40.7Very low68.9Low83 Ų8353.3 Ų53.344%0.44430%0.295SS..SBendtrans161.1178.2166-97.313000111.2A205 H211 R261A205-N209 CarbonylContact O-C 3.57Å; A205-N209 PolarHBondContact O-N 2.97Å; N209-H211 PolarHBondContact O-N 2.97Å; N209-R261 PolarHBondContact ND2-NH2 2.88Å; N209-R261 VanDerWaalsContact ND2-NH2 3.2Å; N209-R261 PolarHBondContact OD1-NH2 2.87Å; N209-R261 VanDerWaalsContact OD1-NH2 3.15Å
210E53.8Low69.4Low146 Ų14648.1 Ų48.168%0.68227%0.271SS*.  trans-43.593.3170.5-168.7172.2-160.100113.4S213E210-S213 PolarHBondContact O-OG 3.19Å; E210-S213 VanDerWaalsContact O-OG 3.13Å
211H57.6Low69.8Low16 Ų1646.3 Ų46.37%0.07426%0.262CS..  trans-91.8-18.6-166.4-169.1-83.5000114.4E146 Y148 A205 N209 S213 R214 S215E146-H211 IonicContact OE1-CE1 3.23Å; E146-H211 PolarHBondContact OE1-CE1 3.07Å; E146-H211 VanDerWaalsContact OE1-CE1 3.28Å; E146-H211 IonicContact OE1-ND1 3.11Å; E146-H211 PolarHBondContact OE1-ND1 3.03Å; E146-H211 IonicContact OE2-CE1 2.72Å; Y148-H211 AromaticContact CD1-NE2 3.86Å; Y148-H211 AromaticContact CD2-CE1 3.85Å; Y148-H211 AromaticContact CD2-NE2 3.63Å; Y148-H211 AromaticContact CE1-NE2 3.84Å; Y148-H211 AromaticContact CE2-NE2 3.63Å; Y148-H211 AromaticContact CG-CE1 3.94Å; Y148-H211 AromaticContact CG-NE2 3.74Å; Y148-H211 AromaticContact CZ-NE2 3.72Å; A205-H211 HydrophobicContact CB-CB 3.57Å; N209-H211 PolarHBondContact O-N 2.97Å; H211-S213 PolarHBondContact O-N 2.81Å; H211-R214 WeakPolarHBondContact O-CA 3.36Å; H211-R214 WeakPolarHBondContact O-CB 3.26Å; H211-R214 PolarHBondContact O-N 2.87Å; H211-S215 PolarHBondContact ND1-OG 3.22Å; H211-S215 PolarHBondContact O-N 2.95Å; H211-S215 PolarHBondContact O-OG 2.79Å
212S62.9Low70.4Confident57 Ų5746.3 Ų46.340%0.39926%0.264SS..THydrogen-bonded Turntrans-67.1-23.7-177.353.10000113.7R201 R214R201-S212 PolarHBondContact NH2-O 2.87Å; S212-R214 VanDerWaalsContact C-N 3.27Å
213S67.7Low71.6Confident17 Ų1743.5 Ų43.512%0.11924%0.244CC..THydrogen-bonded Turntrans-78.1-9170.548.60000113.7T98 E210 H211 A247 G248T98-S213 WeakPolarHBondContact OG1-CB 3.42Å; E210-S213 PolarHBondContact O-OG 3.19Å; E210-S213 VanDerWaalsContact O-OG 3.13Å; H211-S213 PolarHBondContact O-N 2.81Å; S213-A247 WeakPolarHBondContact O-CA 3.47Å; S213-A247 WeakPolarHBondContact O-CB 3.37Å; S213-G248 PolarHBondContact O-N 3.46Å
214R75.2Confident73.1Confident50 Ų5039.7 Ų39.719%0.18922%0.22CC..SBendtrans-120.70.4-165.1-63.6-161.6-179.5-173.3-10.7114.4Y148 H211 S212 E264 I268Y148-R214 WeakPolarHBondContact CD2-O 3.31Å; Y148-R214 HydrophobicContact CE2-CB 4.5Å; H211-R214 WeakPolarHBondContact O-CA 3.36Å; H211-R214 WeakPolarHBondContact O-CB 3.26Å; H211-R214 PolarHBondContact O-N 2.87Å; S212-R214 VanDerWaalsContact C-N 3.27Å; R214-E264 WeakPolarHBondContact CD-OE1 3.22Å; R214-E264 IonicContact CZ-OE1 3.71Å; R214-E264 IonicContact CZ-OE2 3Å; R214-E264 IonicContact NE-OE1 3.95Å; R214-E264 IonicContact NH1-OE1 3.15Å; R214-E264 PolarHBondContact NH1-OE1 3.39Å; R214-E264 IonicContact NH1-OE2 3.16Å; R214-E264 PolarHBondContact NH1-OE2 3.25Å; R214-I268 HydrophobicContact CB-CD1 3.52Å; R214-I268 HydrophobicContact CB-CG1 4.47Å; R214-I268 HydrophobicContact CG-CD1 3.79Å; R214-I268 WeakPolarHBondContact O-CG1 3.47Å
215S85Confident74.7Confident1 Ų138.9 Ų38.91%0.00721%0.212CC..SBendtrans-139148179.367.60000110.9E146 I147 R201 H211E146-S215 WeakPolarHBondContact OE1-CB 3.42Å; E146-S215 PolarHBondContact OE1-OG 2.99Å; I147-S215 WeakPolarHBondContact O-CA 3.4Å; R201-S215 PolarHBondContact NH2-O 3.22Å; R201-S215 PolarHBondContact NH2-OG 3.43Å; H211-S215 PolarHBondContact ND1-OG 3.22Å; H211-S215 PolarHBondContact O-N 2.95Å; H211-S215 PolarHBondContact O-OG 2.79Å
216H90.9Very high76.3Confident4 Ų437.8 Ų37.82%0.01920%0.202CC..EExtended strand (participates in β ladder)trans-91.9122.2173-49.9-73.9000108.8E146 I147 D245 L246 A247 S271 L297E146-H216 CarbonylContact C-O 3.58Å; E146-H216 WeakPolarHBondContact CA-O 3.35Å; I147-H216 HydrophobicContact CB-CB 4.29Å; I147-H216 PolarHBondContact N-O 2.89Å; I147-H216 PolarHBondContact O-N 3.11Å; H216-D245 WeakPolarHBondContact CA-O 3.42Å; H216-L246 HydrophobicContact CB-CD2 4.28Å; H216-L246 WeakPolarHBondContact ND1-CA 3.38Å; H216-L246 WeakPolarHBondContact ND1-CD2 3.27Å; H216-A247 VanDerWaalsContact CE1-CB 3.41Å; H216-A247 WeakPolarHBondContact CE1-CB 3.34Å; H216-A247 PolarHBondContact CE1-N 2.96Å; H216-A247 PolarHBondContact ND1-N 3.23Å; H216-S271 PolarHBondContact NE2-OG 3.28Å; H216-L297 HydrophobicContact CB-CD1 4.28Å
217A93.4Very high78.3Confident1 Ų135.1 Ų35.11%0.00818%0.182CC..EExtended strand (participates in β ladder)trans-99.6129174.200000109.6Y144 R201 V244 D245Y144-A217 HydrophobicContact CE2-CB 3.93Å; R201-A217 VanDerWaalsContact CZ-CB 3.47Å; A217-V244 WeakPolarHBondContact O-CA 3.46Å; A217-D245 HydrophobicContact CB-CB 4.34Å; A217-D245 PolarHBondContact N-O 3.43Å; A217-D245 PolarHBondContact O-N 3Å
218I96.1Very high80Confident5 Ų533.5 Ų33.53%0.02617%0.173CC..EExtended strand (participates in β ladder)trans-124.3107178.4-52.3-174.1000108.9Y144 L145 I147 V220 V244 L297 L300Y144-I218 WeakPolarHBondContact CD2-O 3.09Å; L145-I218 HydrophobicContact CD1-CB 3.81Å; L145-I218 HydrophobicContact CD1-CD1 4.16Å; L145-I218 HydrophobicContact CD1-CG1 4.02Å; L145-I218 HydrophobicContact CG-CB 4.05Å; L145-I218 PolarHBondContact N-O 3.36Å; L145-I218 VanDerWaalsContact N-O 3.07Å; L145-I218 PolarHBondContact O-N 3.23Å; I147-I218 HydrophobicContact CD1-CD1 4.11Å; I218-V220 HydrophobicContact CG2-CG2 3.78Å; I218-V244 HydrophobicContact CD1-CG2 4.46Å; I218-V244 HydrophobicContact CG1-CG1 4.17Å; I218-V244 HydrophobicContact CG1-CG2 4.17Å; I218-V244 HydrophobicContact CG2-CG2 4.08Å; I218-L297 HydrophobicContact CD1-CD1 4.26Å; I218-L300 HydrophobicContact CD1-CD1 4.41Å
219F97.3Very high81.7Confident1 Ų129.2 Ų29.20%0.00416%0.157CC..EExtended strand (participates in β ladder)trans-91.6119.9170.8-163.1-83.3000108.6F123 A142 Y144 I190 V193 M194 I221 L243F123-F219 HydrophobicContact CE1-CD1 4.16Å; F123-F219 AromaticContact CE1-CE1 3.53Å; F123-F219 HydrophobicContact CE1-CE1 3.53Å; F123-F219 HydrophobicContact CE1-CZ 4.07Å; F123-F219 HydrophobicContact CZ-CD1 4.32Å; F123-F219 AromaticContact CZ-CE1 3.65Å; F123-F219 HydrophobicContact CZ-CE1 3.65Å; F123-F219 HydrophobicContact CZ-CE2 4.44Å; F123-F219 AromaticContact CZ-CZ 3.73Å; F123-F219 HydrophobicContact CZ-CZ 3.73Å; A142-F219 HydrophobicContact CB-CE1 4.06Å; A142-F219 HydrophobicContact CB-CZ 3.84Å; Y144-F219 AromaticContact CD1-CD2 3.61Å; Y144-F219 HydrophobicContact CD1-CD2 3.61Å; Y144-F219 AromaticContact CD1-CE2 3.99Å; Y144-F219 HydrophobicContact CD1-CE2 3.99Å; Y144-F219 HydrophobicContact CD2-CB 3.93Å; Y144-F219 AromaticContact CD2-CD2 3.74Å; Y144-F219 HydrophobicContact CD2-CD2 3.74Å; Y144-F219 HydrophobicContact CD2-CG 4.3Å; Y144-F219 HydrophobicContact CE1-CD2 4.06Å; Y144-F219 HydrophobicContact CE2-CB 4.06Å; Y144-F219 HydrophobicContact CE2-CD2 4.14Å; Y144-F219 AromaticContact CG-CD2 3.46Å; Y144-F219 HydrophobicContact CG-CD2 3.46Å; Y144-F219 VanDerWaalsContact CG-CD2 3.46Å; Y144-F219 HydrophobicContact CG-CE2 4.08Å; Y144-F219 HydrophobicContact CG-CG 4.39Å; I190-F219 HydrophobicContact CD1-CE1 4.15Å; I190-F219 HydrophobicContact CD1-CZ 4.43Å; I190-F219 HydrophobicContact CG1-CE1 4.14Å; I190-F219 HydrophobicContact CG1-CZ 3.93Å; V193-F219 HydrophobicContact CG1-CE2 4.35Å; V193-F219 HydrophobicContact CG1-CZ 4.37Å; M194-F219 HydrophobicContact CB-CE2 3.89Å; M194-F219 HydrophobicContact CB-CZ 4.37Å; M194-F219 HydrophobicContact CG-CE2 4.25Å; F219-I221 HydrophobicContact CD1-CG1 3.93Å; F219-I221 HydrophobicContact CE1-CD1 4.36Å; F219-I221 HydrophobicContact CE1-CG1 3.85Å; F219-L243 HydrophobicContact CB-CB 4.29Å; F219-L243 HydrophobicContact CD1-CD1 4.43Å; F219-L243 PolarHBondContact N-O 3.5Å; F219-L243 PolarHBondContact O-N 2.9Å
220V97.1Very high83.3Confident15 Ų1534.7 Ų34.79%0.09119%0.185CC..EExtended strand (participates in β ladder)trans-111.5119.6-175.9-174.70000109A142 S143 I218 K240 L241A142-V220 WeakPolarHBondContact CA-O 3.26Å; S143-V220 PolarHBondContact N-O 3.33Å; S143-V220 PolarHBondContact O-N 2.88Å; I218-V220 HydrophobicContact CG2-CG2 3.78Å; V220-K240 HydrophobicContact CG1-CD 3.82Å; V220-K240 HydrophobicContact CG1-CG 3.63Å; V220-L241 WeakPolarHBondContact CA-O 3.39Å
221I97.3Very high84.4Confident0 Ų032.4 Ų32.40%018%0.178CC..EExtended strand (participates in β ladder)trans-102.9121.8169.3-43-177.9000107.8F123 I126 V140 R141 I190 F219 I223 K240 L241 L243F123-I221 HydrophobicContact CD1-CD1 3.78Å; F123-I221 HydrophobicContact CE1-CD1 3.71Å; I126-I221 HydrophobicContact CD1-CD1 3.75Å; I126-I221 HydrophobicContact CD1-CG2 4.29Å; V140-I221 HydrophobicContact CG1-CG2 3.7Å; R141-I221 CarbonylContact O-C 3.58Å; R141-I221 WeakPolarHBondContact O-CA 3.47Å; I190-I221 HydrophobicContact CD1-CD1 4.15Å; I190-I221 HydrophobicContact CD1-CG1 4.36Å; I190-I221 HydrophobicContact CD1-CG2 4.36Å; F219-I221 HydrophobicContact CD1-CG1 3.93Å; F219-I221 HydrophobicContact CE1-CD1 4.36Å; F219-I221 HydrophobicContact CE1-CG1 3.85Å; I221-I223 HydrophobicContact CG2-CG1 4.09Å; I221-K240 CarbonylContact O-C 3.6Å; I221-K240 WeakPolarHBondContact O-CA 3.28Å; I221-L241 HydrophobicContact CB-CB 4.3Å; I221-L241 HydrophobicContact CD1-CD2 4.25Å; I221-L241 PolarHBondContact N-O 3.19Å; I221-L241 PolarHBondContact O-N 2.66Å; I221-L243 HydrophobicContact CD1-CD1 3.94Å; I221-L243 HydrophobicContact CG1-CD1 4.24Å
222T95.3Very high85.1Confident18 Ų1834.1 Ų34.111%0.1120%0.199CC..EExtended strand (participates in β ladder)trans-105.7123.7170.3-52.30000108.4V140 R141 V238V140-T222 WeakPolarHBondContact CA-O 3.41Å; R141-T222 PolarHBondContact N-O 3.46Å; R141-T222 PolarHBondContact O-N 2.85Å; T222-V238 HydrophobicContact CG2-CG1 3.97Å
223I94.2Very high85.7Confident3 Ų337.8 Ų37.82%0.01521%0.21CC..EExtended strand (participates in β ladder)trans-114.8112.5179.6-51.8177000106.9V84 L85 I126 Y138 V140 I221 G239V84-I223 HydrophobicContact CG1-CD1 4.11Å; L85-I223 HydrophobicContact CD2-CD1 3.93Å; L85-I223 HydrophobicContact CG-CD1 4.36Å; I126-I223 HydrophobicContact CD1-CD1 3.83Å; I126-I223 HydrophobicContact CG1-CD1 3.87Å; I126-I223 HydrophobicContact CG2-CD1 3.87Å; Y138-I223 HydrophobicContact CD1-CG2 3.83Å; Y138-I223 HydrophobicContact CE1-CG2 4.28Å; V140-I223 HydrophobicContact CG2-CG2 4.5Å; I221-I223 HydrophobicContact CG2-CG1 4.09Å; I223-G239 PolarHBondContact N-O 3.08Å; I223-G239 PolarHBondContact O-N 3.42Å
224E92.3Very high86.1Confident3 Ų341.3 Ų41.31%0.01423%0.228CC..EExtended strand (participates in β ladder)trans-99.1131.8168.1-60.5179-170.300108.3Y138 L139 R141 R237 V238 L354 L355Y138-E224 CarbonylContact C-O 3.53Å; Y138-E224 VanDerWaalsContact CA-O 3.3Å; Y138-E224 WeakPolarHBondContact CA-O 3.33Å; L139-E224 HydrophobicContact CB-CB 4.32Å; L139-E224 PolarHBondContact N-O 2.88Å; L139-E224 PolarHBondContact O-N 3.41Å; R141-E224 IonicContact CZ-OE1 2.73Å; R141-E224 IonicContact NH1-OE1 2.59Å; R141-E224 PolarHBondContact NH1-OE1 2.8Å; R141-E224 IonicContact NH1-OE2 2.93Å; R141-E224 PolarHBondContact NH1-OE2 3.12Å; R141-E224 IonicContact NH2-OE1 3.67Å; R141-E224 PolarHBondContact NH2-OE1 3.43Å; E224-R237 WeakPolarHBondContact CA-O 3.3Å; E224-V238 HydrophobicContact CG-CG1 4.05Å; E224-V238 HydrophobicContact CG-CG2 4.04Å; E224-L354 PolarHBondContact OE2-N 2.88Å; E224-L354 VanDerWaalsContact OE2-N 3.12Å; E224-L355 HydrophobicContact CB-CB 4.07Å; E224-L355 HydrophobicContact CB-CD1 4.02Å; E224-L355 WeakPolarHBondContact OE2-CB 3.29Å; E224-L355 PolarHBondContact OE2-N 2.85Å
225C90.1Very high86.5Confident2 Ų242.5 Ų42.51%0.01424%0.235CC..EExtended strand (participates in β ladder)trans-123.9127.3178.7177.90000108.8Q137 Y138 I236 R237Q137-C225 CarbonylContact O-C 3.53Å; Q137-C225 WeakPolarHBondContact O-CA 3.32Å; Y138-C225 HydrophobicContact CD1-CB 3.9Å; Y138-C225 HydrophobicContact CE1-CB 3.67Å; Y138-C225 VanDerWaalsContact CZ-SG 3.58Å; C225-I236 CarbonylContact O-C 3.53Å; C225-I236 WeakPolarHBondContact O-CA 3.5Å; C225-R237 PolarHBondContact N-O 2.92Å; C225-R237 PolarHBondContact O-N 3.5Å
226S87.6Confident86.6Confident3 Ų342.9 Ų42.92%0.02124%0.237CC..EExtended strand (participates in β ladder)trans-110.3131168.9171.30000109.5Q136 Q137 H235 Q359Q136-S226 WeakPolarHBondContact CA-O 3.25Å; Q137-S226 PolarHBondContact N-O 3.33Å; Q137-S226 PolarHBondContact O-N 3.44Å; S226-H235 WeakPolarHBondContact CA-O 3.32Å; S226-Q359 PolarHBondContact OG-NE2 3.47Å
227E85.6Confident86.6Confident60 Ų6044 Ų4428%0.2824%0.241SC..EExtended strand (participates in β ladder)trans-135.7136.5-178.6179.5168.8-138.800109.1Q136 G229 H235 R237Q136-E227 HydrophobicContact CG-CB 4.13Å; Q136-E227 HydrophobicContact CG-CG 4.05Å; Q136-E227 VanDerWaalsContact NE2-CD 3.33Å; Q136-E227 PolarHBondContact NE2-OE1 3.17Å; E227-G229 PolarHBondContact O-N 3.49Å; E227-H235 PolarHBondContact N-O 3.17Å; E227-H235 PolarHBondContact O-N 2.95Å; E227-R237 IonicContact OE2-CZ 3.72Å; E227-R237 IonicContact OE2-NH1 3.74Å; E227-R237 PolarHBondContact OE2-NH1 3.3Å; E227-R237 IonicContact OE2-NH2 2.67Å; E227-R237 PolarHBondContact OE2-NH2 3.46Å
228L79.9Confident86.5Confident108 Ų10845.5 Ų45.557%0.56525%0.25SS*.EExtended strand (participates in β ladder)trans-75.7117.4172.1-164.978.7000108.6G232 N234L228-G232 WeakPolarHBondContact CD1-O 3.28Å; L228-N234 WeakPolarHBondContact CD1-OD1 3.46Å
229G75.9Confident86.4Confident21 Ų2145.3 Ų45.322%0.21625%0.25CC..  trans-71.3168.1178.200000112.8E227 D231 G232 E233E227-G229 PolarHBondContact O-N 3.49Å; G229-D231 VanDerWaalsContact CA-OD1 3.31Å; G229-D231 WeakPolarHBondContact CA-OD1 3.45Å; G229-D231 PolarHBondContact O-N 2.92Å; G229-G232 PolarHBondContact O-N 2.87Å; G229-E233 PolarHBondContact N-O 2.99Å
230L74.8Confident86.3Confident197 Ų19748.3 Ų48.3100%1.03126%0.263SS*.THydrogen-bonded Turntrans-67.7-13.8173.7-61.2176.6000112.9G232L230-G232 VanDerWaalsContact C-N 3.35Å
231D76.3Confident86.3Confident99 Ų9947.6 Ų47.653%0.52926%0.258SS..THydrogen-bonded Turntrans-81.7-10.9170.448.316.2000113.1G229 E233 H235G229-D231 VanDerWaalsContact CA-OD1 3.31Å; G229-D231 WeakPolarHBondContact CA-OD1 3.45Å; G229-D231 PolarHBondContact O-N 2.92Å; D231-E233 VanDerWaalsContact C-N 3.32Å; D231-E233 PolarHBondContact OD1-N 3Å; D231-H235 IonicContact OD1-CD2 2.8Å; D231-H235 IonicContact OD1-NE2 3.04Å; D231-H235 PolarHBondContact OD1-NE2 2.76Å; D231-H235 IonicContact OD2-CD2 3.24Å; D231-H235 IonicContact OD2-CE1 2.81Å; D231-H235 PolarHBondContact OD2-CE1 2.69Å; D231-H235 IonicContact OD2-NE2 2.66Å; D231-H235 PolarHBondContact OD2-NE2 3.28Å
232G71.4Confident86.3Confident51 Ų5148.7 Ų48.753%0.52626%0.264SS..SBendtrans81.65.2-174.200000114.3L228 G229 L230L228-G232 WeakPolarHBondContact CD1-O 3.28Å; G229-G232 PolarHBondContact O-N 2.87Å; L230-G232 VanDerWaalsContact C-N 3.35Å
233E76.5Confident86.4Confident135 Ų13547.9 Ų47.963%0.63126%0.259SS*.  trans-91.8150174.8-63.4-161.816300111.3G229 D231 H235G229-E233 PolarHBondContact N-O 2.99Å; D231-E233 VanDerWaalsContact C-N 3.32Å; D231-E233 PolarHBondContact OD1-N 3Å; E233-H235 PolarHBondContact O-CD2 3.11Å; E233-H235 PolarHBondContact O-N 2.75Å
234N76.6Confident86.5Confident91 Ų9147.8 Ų47.849%0.48726%0.258SS..EExtended strand (participates in β ladder)trans-82.8104.4174.8-87.1-26.5000110.1L228L228-N234 WeakPolarHBondContact CD1-OD1 3.46Å
235H83.4Confident86.7Confident75 Ų7548 Ų4835%0.34726%0.26SS..EExtended strand (participates in β ladder)trans-82.6128.9173.1-68.6-88000109.6S226 E227 D231 E233S226-H235 WeakPolarHBondContact CA-O 3.32Å; E227-H235 PolarHBondContact N-O 3.17Å; E227-H235 PolarHBondContact O-N 2.95Å; D231-H235 IonicContact OD1-CD2 2.8Å; D231-H235 IonicContact OD1-NE2 3.04Å; D231-H235 PolarHBondContact OD1-NE2 2.76Å; D231-H235 IonicContact OD2-CD2 3.24Å; D231-H235 IonicContact OD2-CE1 2.81Å; D231-H235 PolarHBondContact OD2-CE1 2.69Å; D231-H235 IonicContact OD2-NE2 2.66Å; D231-H235 PolarHBondContact OD2-NE2 3.28Å; E233-H235 PolarHBondContact O-CD2 3.11Å; E233-H235 PolarHBondContact O-N 2.75Å
236I87.3Confident86.8Confident9 Ų947.9 Ų47.95%0.04626%0.259CS..EExtended strand (participates in β ladder)trans-114.1126.9178.7-53.6178.3000109.5C225 E348 A353 L355 R356C225-I236 CarbonylContact O-C 3.53Å; C225-I236 WeakPolarHBondContact O-CA 3.5Å; I236-E348 CarbonylContact O-C 3.55Å; I236-E348 WeakPolarHBondContact O-CA 3.49Å; I236-A353 HydrophobicContact CB-CB 4.45Å; I236-A353 HydrophobicContact CD1-CB 4.33Å; I236-A353 HydrophobicContact CG2-CB 3.58Å; I236-L355 HydrophobicContact CD1-CD2 4.36Å; I236-R356 HydrophobicContact CD1-CB 3.69Å; I236-R356 HydrophobicContact CD1-CG 4.26Å
237R90.6Very high86.8Confident27 Ų2747.7 Ų47.710%0.10226%0.258CS..EExtended strand (participates in β ladder)trans-118.4139.6179.9-60-170.1-65.6-87.42.8110.5E224 C225 E227 V346 N347 E348E224-R237 WeakPolarHBondContact CA-O 3.3Å; C225-R237 PolarHBondContact N-O 2.92Å; C225-R237 PolarHBondContact O-N 3.5Å; E227-R237 IonicContact OE2-CZ 3.72Å; E227-R237 IonicContact OE2-NH1 3.74Å; E227-R237 PolarHBondContact OE2-NH1 3.3Å; E227-R237 IonicContact OE2-NH2 2.67Å; E227-R237 PolarHBondContact OE2-NH2 3.46Å; R237-V346 HydrophobicContact CG-CG1 4.22Å; R237-N347 WeakPolarHBondContact CA-O 3.29Å; R237-E348 HydrophobicContact CG-CG 4.3Å
238V91.6Very high86.8Confident33 Ų3344.9 Ų44.920%0.225%0.245CC..EExtended strand (participates in β ladder)trans-124.2105.9-177-172.20000111T222 E224 N347 A353T222-V238 HydrophobicContact CG2-CG1 3.97Å; E224-V238 HydrophobicContact CG-CG1 4.05Å; E224-V238 HydrophobicContact CG-CG2 4.04Å; V238-N347 PolarHBondContact N-O 3.35Å; V238-N347 WeakPolarHBondContact O-CB 3.37Å; V238-N347 PolarHBondContact O-ND2 2.69Å; V238-A353 HydrophobicContact CG2-CB 4.49Å
239G93.1Very high87Confident1 Ų140.5 Ų40.51%0.0122%0.223CC..EExtended strand (participates in β ladder)trans-97.6129.217300000111.7F88 I223F88-G239 WeakPolarHBondContact O-CA 3.18Å; I223-G239 PolarHBondContact N-O 3.08Å; I223-G239 PolarHBondContact O-N 3.42Å
240K94.5Very high87Confident64 Ų6441.1 Ų41.128%0.27822%0.221SC..EExtended strand (participates in β ladder)trans-109.6120.1169.9-175.2-178-73.41720110.3N89 G90 V220 I221N89-K240 CarbonylContact C-O 3.55Å; N89-K240 WeakPolarHBondContact CA-O 3.47Å; N89-K240 PolarHBondContact OD1-N 3.43Å; G90-K240 PolarHBondContact N-O 2.68Å; V220-K240 HydrophobicContact CG1-CD 3.82Å; V220-K240 HydrophobicContact CG1-CG 3.63Å; I221-K240 CarbonylContact O-C 3.6Å; I221-K240 WeakPolarHBondContact O-CA 3.28Å
241L97.5Very high86.4Confident0 Ų034 Ų340%018%0.18CC..EExtended strand (participates in β ladder)trans-100.9114.5170.317958.5000110L80 V81 V84 G90 I92 I126 V220 I221 L243L80-L241 HydrophobicContact CD2-CD1 4.33Å; V81-L241 HydrophobicContact CG2-CD2 4.04Å; V84-L241 HydrophobicContact CB-CB 4.49Å; V84-L241 HydrophobicContact CG1-CB 4.04Å; V84-L241 HydrophobicContact CG2-CB 4.12Å; V84-L241 HydrophobicContact CG2-CD1 4.28Å; G90-L241 CarbonylContact O-C 3.4Å; G90-L241 VanDerWaalsContact O-CA 3.29Å; G90-L241 WeakPolarHBondContact O-CA 3.19Å; I92-L241 HydrophobicContact CG1-CD1 4.42Å; I126-L241 HydrophobicContact CD1-CD2 4.39Å; V220-L241 WeakPolarHBondContact CA-O 3.39Å; I221-L241 HydrophobicContact CB-CB 4.3Å; I221-L241 HydrophobicContact CD1-CD2 4.25Å; I221-L241 PolarHBondContact N-O 3.19Å; I221-L241 PolarHBondContact O-N 2.66Å; L241-L243 HydrophobicContact CD1-CG 4.49Å; L241-L243 HydrophobicContact CD2-CD1 3.98Å; L241-L243 HydrophobicContact CD2-CD2 4.49Å; L241-L243 HydrophobicContact CD2-CG 4.26Å; L241-L243 HydrophobicContact CG-CD1 4.11Å; L241-L243 HydrophobicContact CG-CG 4.03Å
242N97.6Very high85.6Confident22 Ų2232 Ų3212%0.11817%0.167CC..EExtended strand (participates in β ladder)trans-96.5122.8171-51.4-65000109.8G90 T91 I92 V244G90-N242 PolarHBondContact O-N 2.9Å; T91-N242 CarbonylContact C-O 3.54Å; T91-N242 WeakPolarHBondContact CA-O 3.25Å; T91-N242 HydrophobicContact CG2-CB 4.14Å; T91-N242 PolarHBondContact OG1-ND2 3.02Å; I92-N242 PolarHBondContact N-O 3.23Å; N242-V244 HydrophobicContact CB-CG2 4.39Å
243L97.6Very high84.9Confident2 Ų234.2 Ų34.21%0.0118%0.181CC..EExtended strand (participates in β ladder)trans-113.2107.3176.6-68.2148.3000108.2I92 M106 V118 I119 F219 I221 L241I92-L243 HydrophobicContact CB-CD2 4.27Å; I92-L243 HydrophobicContact CD1-CD2 4.05Å; I92-L243 HydrophobicContact CG1-CD2 4.48Å; M106-L243 HydrophobicContact CE-CB 3.88Å; M106-L243 HydrophobicContact CE-CD2 4.1Å; V118-L243 HydrophobicContact CG1-CD2 4.25Å; V118-L243 HydrophobicContact CG2-CD2 4.09Å; I119-L243 HydrophobicContact CD1-CB 4.3Å; I119-L243 HydrophobicContact CG1-CB 3.85Å; I119-L243 HydrophobicContact CG1-CD1 4.09Å; I119-L243 HydrophobicContact CG1-CD2 4.06Å; I119-L243 HydrophobicContact CG1-CG 4.21Å; I119-L243 HydrophobicContact CG2-CD1 4.41Å; F219-L243 HydrophobicContact CB-CB 4.29Å; F219-L243 HydrophobicContact CD1-CD1 4.43Å; F219-L243 PolarHBondContact N-O 3.5Å; F219-L243 PolarHBondContact O-N 2.9Å; I221-L243 HydrophobicContact CD1-CD1 3.94Å; I221-L243 HydrophobicContact CG1-CD1 4.24Å; L241-L243 HydrophobicContact CD1-CG 4.49Å; L241-L243 HydrophobicContact CD2-CD1 3.98Å; L241-L243 HydrophobicContact CD2-CD2 4.49Å; L241-L243 HydrophobicContact CD2-CG 4.26Å; L241-L243 HydrophobicContact CG-CD1 4.11Å; L241-L243 HydrophobicContact CG-CG 4.03Å
244V97Very high83.9Confident0 Ų031.9 Ų31.90%017%0.169CC..EExtended strand (participates in β ladder)trans-113.6119.6-166.8-177.40000111.1T91 I92 F93 A94 A217 I218 N242 L246 L301T91-V244 HydrophobicContact CG2-CG2 4.35Å; I92-V244 PolarHBondContact O-N 3.18Å; F93-V244 WeakPolarHBondContact CA-O 3.43Å; F93-V244 HydrophobicContact CB-CB 3.66Å; F93-V244 HydrophobicContact CB-CG1 4.06Å; F93-V244 HydrophobicContact CB-CG2 4.31Å; A94-V244 PolarHBondContact N-O 3.43Å; A217-V244 WeakPolarHBondContact O-CA 3.46Å; I218-V244 HydrophobicContact CD1-CG2 4.46Å; I218-V244 HydrophobicContact CG1-CG1 4.17Å; I218-V244 HydrophobicContact CG1-CG2 4.17Å; I218-V244 HydrophobicContact CG2-CG2 4.08Å; N242-V244 HydrophobicContact CB-CG2 4.39Å; V244-L246 HydrophobicContact CG1-CD2 3.4Å; V244-L246 VanDerWaalsContact CG1-CD2 3.4Å; V244-L246 HydrophobicContact CG1-CG 3.87Å; V244-L301 HydrophobicContact CG2-CD2 4.08Å
245D95.1Very high82.9Confident7 Ų730.8 Ų30.84%0.03717%0.165CC..EExtended strand (participates in β ladder)trans-103.8101.6168.8-172.537.3000107.9K102 T103 M106 R201 H216 A217K102-D245 WeakPolarHBondContact CB-OD1 3.43Å; T103-D245 WeakPolarHBondContact CA-OD1 3.02Å; T103-D245 WeakPolarHBondContact CB-OD2 3.26Å; T103-D245 WeakPolarHBondContact CG2-OD2 3.41Å; T103-D245 PolarHBondContact N-OD1 2.93Å; T103-D245 VanDerWaalsContact N-OD1 3.08Å; T103-D245 PolarHBondContact OG1-OD1 3.27Å; T103-D245 PolarHBondContact OG1-OD2 2.85Å; M106-D245 HydrophobicContact CB-CB 4.29Å; M106-D245 HydrophobicContact CG-CB 4.01Å; R201-D245 IonicContact NH1-OD2 3.35Å; R201-D245 PolarHBondContact NH1-OD2 2.7Å; H216-D245 WeakPolarHBondContact CA-O 3.42Å; A217-D245 HydrophobicContact CB-CB 4.34Å; A217-D245 PolarHBondContact N-O 3.43Å; A217-D245 PolarHBondContact O-N 3Å
246L92.3Very high81.6Confident0 Ų030.4 Ų30.40%018%0.182CC..PPolyproline II helixtrans-76.7163.4-177.3-61.5175.9000112F93 A94 Y95 K102 H216 V244 L272 L275 L297F93-L246 HydrophobicContact CD2-CD1 3.86Å; A94-L246 VanDerWaalsContact O-CB 3.3Å; A94-L246 WeakPolarHBondContact O-CB 3.47Å; A94-L246 WeakPolarHBondContact O-CG 3.46Å; A94-L246 PolarHBondContact O-N 2.8Å; Y95-L246 HydrophobicContact CD2-CD1 3.82Å; Y95-L246 HydrophobicContact CG-CD1 4.47Å; K102-L246 WeakPolarHBondContact CE-O 3.24Å; H216-L246 HydrophobicContact CB-CD2 4.28Å; H216-L246 WeakPolarHBondContact ND1-CA 3.38Å; H216-L246 WeakPolarHBondContact ND1-CD2 3.27Å; V244-L246 HydrophobicContact CG1-CD2 3.4Å; V244-L246 VanDerWaalsContact CG1-CD2 3.4Å; V244-L246 HydrophobicContact CG1-CG 3.87Å; L246-L272 HydrophobicContact CB-CD2 4.46Å; L246-L272 HydrophobicContact CD1-CD2 4.3Å; L246-L275 HydrophobicContact CD1-CD2 4.04Å; L246-L297 HydrophobicContact CD2-CD1 3.89Å; L246-L297 HydrophobicContact CD2-CD2 3.85Å; L246-L297 HydrophobicContact CD2-CG 4.49Å
247A88.6Confident80.2Confident0 Ų031 Ų310%019%0.188CC..PPolyproline II helixtrans-63.8172.1168.500000112.8K102 S213 H216 I268 L272K102-A247 WeakPolarHBondContact CE-O 3.39Å; K102-A247 PolarHBondContact NZ-O 2.83Å; S213-A247 WeakPolarHBondContact O-CA 3.47Å; S213-A247 WeakPolarHBondContact O-CB 3.37Å; H216-A247 VanDerWaalsContact CE1-CB 3.41Å; H216-A247 WeakPolarHBondContact CE1-CB 3.34Å; H216-A247 PolarHBondContact CE1-N 2.96Å; H216-A247 PolarHBondContact ND1-N 3.23Å; A247-I268 HydrophobicContact CB-CG2 3.78Å; A247-L272 HydrophobicContact CB-CD1 4.4Å
248G85.3Confident78.3Confident1 Ų137.7 Ų37.71%0.0122%0.221CC..PPolyproline II helixtrans-62.5133.317200000112.9T98 S213 E250 L272T98-G248 WeakPolarHBondContact OG1-CA 3.48Å; S213-G248 PolarHBondContact O-N 3.46Å; G248-E250 VanDerWaalsContact C-N 3.29Å; G248-E250 VanDerWaalsContact C-OE2 3.29Å; G248-E250 WeakPolarHBondContact CA-OE2 3.4Å; G248-L272 WeakPolarHBondContact O-CD1 3.34Å
249S83.3Confident77.2Confident15 Ų1538.7 Ų38.711%0.10524%0.238CC..  trans-84.74.5176.970.50000114.5G96 Q97G96-S249 WeakPolarHBondContact CA-OG 3.48Å; G96-S249 PolarHBondContact O-N 3.31Å; G96-S249 VanDerWaalsContact O-N 3.16Å; G96-S249 PolarHBondContact O-OG 3.35Å; Q97-S249 PolarHBondContact N-OG 2.89Å; Q97-S249 VanDerWaalsContact N-OG 3.12Å
250E75.7Confident75.6Confident35 Ų3545.8 Ų45.816%0.16427%0.271CS..  trans-65.8144.1-175.852.9-86.3-164.500114.8Q97 T98 G248 N269 E326Q97-E250 WeakPolarHBondContact CA-OE2 3.3Å; Q97-E250 HydrophobicContact CG-CB 4.26Å; T98-E250 WeakPolarHBondContact CB-OE1 3.25Å; T98-E250 PolarHBondContact N-OE2 3.19Å; T98-E250 PolarHBondContact OG1-OE1 3.41Å; T98-E250 PolarHBondContact OG1-OE2 3.32Å; G248-E250 VanDerWaalsContact C-N 3.29Å; G248-E250 VanDerWaalsContact C-OE2 3.29Å; G248-E250 WeakPolarHBondContact CA-OE2 3.4Å; E250-N269 PolarHBondContact O-ND2 3.34Å; E250-E326 WeakPolarHBondContact CA-OE2 3.09Å
251R64.1Low74.1Confident46 Ų4647.5 Ų47.517%0.17428%0.275CS..  trans-67.4135.9173.4-63.2-169.8-178.6-127.4-3.3111.7A253 K254 E554 E558 E561R251-A253 PolarHBondContact O-N 2.66Å; R251-A253 VanDerWaalsContact O-N 3.09Å; R251-K254 PolarHBondContact O-N 3.35Å; R251-K254 VanDerWaalsContact O-N 3.1Å; R251-E554 IonicContact NH2-OE1 3.86Å; R251-E554 PolarHBondContact NH2-OE1 3.35Å; R251-E558 IonicContact NH2-OE1 3.86Å; R251-E558 PolarHBondContact NH2-OE1 3.47Å; R251-E558 VanDerWaalsContact NH2-OE1 3.15Å; R251-E561 IonicContact NH1-OE1 2.62Å; R251-E561 PolarHBondContact NH1-OE1 3.32Å; R251-E561 VanDerWaalsContact NH1-OE1 3.17Å; R251-E561 IonicContact NH1-OE2 3.83Å; R251-E561 PolarHBondContact NH1-OE2 2.82Å; R251-E561 VanDerWaalsContact NH1-OE2 3.11Å
252Q58.8Low72.4Confident57 Ų5750.7 Ų50.727%0.26629%0.292SS..G310 helixtrans-49.3-38.4-178.9-83.9156.942.900114K254 T255 A265 N269Q252-K254 PolarHBondContact O-N 2.9Å; Q252-T255 WeakPolarHBondContact O-CB 3.43Å; Q252-T255 PolarHBondContact O-N 3.26Å; Q252-T255 PolarHBondContact O-OG1 2.79Å; Q252-A265 HydrophobicContact CG-CB 3.89Å; Q252-A265 PolarHBondContact NE2-O 2.85Å; Q252-A265 VanDerWaalsContact NE2-O 3.16Å; Q252-N269 PolarHBondContact NE2-ND2 3.02Å
253A56Low70.9Confident98 Ų9855.9 Ų55.981%0.8131%0.314SS*.G310 helixtrans-54.7-26.6-178.900000114.2R251R251-A253 PolarHBondContact O-N 2.66Å; R251-A253 VanDerWaalsContact O-N 3.09Å
254K55.5Low69.3Low86 Ų8656.4 Ų56.437%0.37432%0.316SS..G310 helixtrans-82.1-12.6176.8-73.7176.2-179.4162.80114.3R251 Q252 E325 E326R251-K254 PolarHBondContact O-N 3.35Å; R251-K254 VanDerWaalsContact O-N 3.1Å; Q252-K254 PolarHBondContact O-N 2.9Å; K254-E325 VanDerWaalsContact CE-OE2 3.32Å; K254-E325 WeakPolarHBondContact CE-OE2 3.49Å; K254-E325 IonicContact NZ-OE2 2.66Å; K254-E325 PolarHBondContact NZ-OE2 3.08Å; K254-E326 WeakPolarHBondContact CD-OE1 3.34Å; K254-E326 WeakPolarHBondContact CE-OE1 3.45Å; K254-E326 IonicContact NZ-OE1 2.6Å; K254-E326 PolarHBondContact NZ-OE1 3.2Å
255T56.3Low67.7Low68 Ų6857 Ų5742%0.41732%0.321SS..THydrogen-bonded Turntrans-89.5-19-172.669.90000114Q252 A257Q252-T255 WeakPolarHBondContact O-CB 3.43Å; Q252-T255 PolarHBondContact O-N 3.26Å; Q252-T255 PolarHBondContact O-OG1 2.79Å; T255-A257 PolarHBondContact O-N 2.95Å; T255-A257 VanDerWaalsContact O-N 3.16Å
256G57Low66.3Low68 Ų6859.5 Ų59.570%0.70134%0.336SS*.  trans60.519.3-178.100000114.7
257A56.6Low65.1Low21 Ų2163.5 Ų63.517%0.17435%0.353CS..  trans-71.6136.8-174.400000112.5T255 R261T255-A257 PolarHBondContact O-N 2.95Å; T255-A257 VanDerWaalsContact O-N 3.16Å; A257-R261 HydrophobicContact CB-CB 4.05Å
258Q51.6Low64.1Low168 Ų16864 Ų6479%0.78536%0.356SS*.  trans-125.4157.4175.1-66-175.6-10.700110.8
259G68Low63.3Low54 Ų5465.4 Ų65.456%0.55736%0.364SS*.THydrogen-bonded Turntrans67.6-136.1174.600000113.7R261 L262 K263G259-R261 PolarHBondContact O-N 2.83Å; G259-L262 VanDerWaalsContact O-CB 3.31Å; G259-L262 WeakPolarHBondContact O-CB 3.33Å; G259-L262 PolarHBondContact O-N 2.8Å; G259-K263 PolarHBondContact O-N 3.24Å
260E59.7Low63.2Low150 Ų15068.8 Ų68.870%0.70138%0.38SS*.Hα-helixtrans-60-33.2-179.6-64.8-172140.400113L262 K263 E264E260-L262 PolarHBondContact O-N 2.91Å; E260-K263 PolarHBondContact O-N 2.68Å; E260-E264 WeakPolarHBondContact O-CB 3.31Å; E260-E264 PolarHBondContact O-N 3.34Å
261R62Low63.6Low99 Ų9967.1 Ų67.137%0.37437%0.372SS..Hα-helixtrans-64.3-25.7175.3-69.9179.4172.3164.30.7113M208 N209 A257 G259 A265M208-R261 PolarHBondContact O-NH2 3.28Å; M208-R261 VanDerWaalsContact O-NH2 3.08Å; N209-R261 PolarHBondContact ND2-NH2 2.88Å; N209-R261 VanDerWaalsContact ND2-NH2 3.2Å; N209-R261 PolarHBondContact OD1-NH2 2.87Å; N209-R261 VanDerWaalsContact OD1-NH2 3.15Å; A257-R261 HydrophobicContact CB-CB 4.05Å; G259-R261 PolarHBondContact O-N 2.83Å; R261-A265 WeakPolarHBondContact O-CB 3.47Å; R261-A265 PolarHBondContact O-N 2.89Å
262L62.8Low64.6Low68 Ų6865.4 Ų65.436%0.35637%0.366SS..Hα-helixtrans-71.3-50.4172.7-176.463.4000109.9G259 E260 E264 A265 T266G259-L262 VanDerWaalsContact O-CB 3.31Å; G259-L262 WeakPolarHBondContact O-CB 3.33Å; G259-L262 PolarHBondContact O-N 2.8Å; E260-L262 PolarHBondContact O-N 2.91Å; L262-E264 VanDerWaalsContact C-N 3.25Å; L262-E264 PolarHBondContact O-N 3.49Å; L262-A265 PolarHBondContact O-N 2.75Å; L262-T266 PolarHBondContact O-N 3.1Å; L262-T266 PolarHBondContact O-OG1 3.05Å
263K65.8Low65.8Low131 Ų13165.8 Ų65.857%0.5738%0.376SS*.Hα-helixtrans-57.8-37.8176.6-64.5-172.3172.9-171.10112.6G259 E260 K267 E572G259-K263 PolarHBondContact O-N 3.24Å; E260-K263 PolarHBondContact O-N 2.68Å; K263-K267 PolarHBondContact O-N 3.03Å; K263-E572 IonicContact NZ-OE1 3.75Å
264E64.5Low67.4Low13 Ų1361.2 Ų61.26%0.06134%0.338CS..Hα-helixtrans-61.7-52.1171.7-174.5-165.8163.400111.4Y148 Q149 R214 E260 L262 T266 K267 I268Y148-E264 HydrophobicContact CE2-CG 4.15Å; Y148-E264 PolarHBondContact OH-OE1 3.03Å; Q149-E264 HydrophobicContact CG-CG 4.48Å; R214-E264 WeakPolarHBondContact CD-OE1 3.22Å; R214-E264 IonicContact CZ-OE1 3.71Å; R214-E264 IonicContact CZ-OE2 3Å; R214-E264 IonicContact NE-OE1 3.95Å; R214-E264 IonicContact NH1-OE1 3.15Å; R214-E264 PolarHBondContact NH1-OE1 3.39Å; R214-E264 IonicContact NH1-OE2 3.16Å; R214-E264 PolarHBondContact NH1-OE2 3.25Å; E260-E264 WeakPolarHBondContact O-CB 3.31Å; E260-E264 PolarHBondContact O-N 3.34Å; L262-E264 VanDerWaalsContact C-N 3.25Å; L262-E264 PolarHBondContact O-N 3.49Å; E264-T266 VanDerWaalsContact C-N 3.31Å; E264-T266 PolarHBondContact O-N 2.98Å; E264-K267 PolarHBondContact O-N 2.75Å; E264-K267 VanDerWaalsContact O-N 3.13Å; E264-I268 HydrophobicContact CG-CD1 3.99Å; E264-I268 VanDerWaalsContact O-CG1 3.31Å; E264-I268 WeakPolarHBondContact O-CG1 3.39Å; E264-I268 PolarHBondContact O-N 3.35Å
265A63Low69.1Low12 Ų1257.2 Ų57.210%0.09932%0.32CS..Hα-helixtrans-63.1-32.9178.900000113.4Q252 R261 L262 I268 N269Q252-A265 HydrophobicContact CG-CB 3.89Å; Q252-A265 PolarHBondContact NE2-O 2.85Å; Q252-A265 VanDerWaalsContact NE2-O 3.16Å; R261-A265 WeakPolarHBondContact O-CB 3.47Å; R261-A265 PolarHBondContact O-N 2.89Å; L262-A265 PolarHBondContact O-N 2.75Å; A265-I268 PolarHBondContact O-N 3.07Å; A265-N269 PolarHBondContact O-N 2.96Å; A265-N269 VanDerWaalsContact O-N 3.13Å
266T65.4Low70.6Confident59 Ų5954.5 Ų54.536%0.36231%0.306SS..Hα-helixtrans-59.7-48.2170.8-48.40000111.4L262 E264 N269 L270L262-T266 PolarHBondContact O-N 3.1Å; L262-T266 PolarHBondContact O-OG1 3.05Å; E264-T266 VanDerWaalsContact C-N 3.31Å; E264-T266 PolarHBondContact O-N 2.98Å; T266-N269 PolarHBondContact O-N 3.05Å; T266-L270 PolarHBondContact O-N 3.03Å
267K68.1Low72Confident84 Ų8455.4 Ų55.437%0.36530%0.295SS..Hα-helixtrans-68.7-33.6179.1-72.8-175.6164.5-161.40113.6Q149 K263 E264 L270Q149-K267 HydrophobicContact CB-CD 3.65Å; Q149-K267 HydrophobicContact CG-CD 4.15Å; Q149-K267 PolarHBondContact O-NZ 3.24Å; K263-K267 PolarHBondContact O-N 3.03Å; E264-K267 PolarHBondContact O-N 2.75Å; E264-K267 VanDerWaalsContact O-N 3.13Å; K267-L270 WeakPolarHBondContact O-CB 3.35Å; K267-L270 PolarHBondContact O-N 3.1Å
268I66.3Low73.7Confident12 Ų1254.4 Ų54.46%0.06229%0.287CS..Hα-helixtrans-63.9-49.2176.4-65.6161.1000109.5R214 A247 E264 A265 L270 S271R214-I268 HydrophobicContact CB-CD1 3.52Å; R214-I268 HydrophobicContact CB-CG1 4.47Å; R214-I268 HydrophobicContact CG-CD1 3.79Å; R214-I268 WeakPolarHBondContact O-CG1 3.47Å; A247-I268 HydrophobicContact CB-CG2 3.78Å; E264-I268 HydrophobicContact CG-CD1 3.99Å; E264-I268 VanDerWaalsContact O-CG1 3.31Å; E264-I268 WeakPolarHBondContact O-CG1 3.39Å; E264-I268 PolarHBondContact O-N 3.35Å; A265-I268 PolarHBondContact O-N 3.07Å; I268-L270 VanDerWaalsContact C-N 3.33Å; I268-L270 PolarHBondContact O-N 3.49Å; I268-S271 PolarHBondContact O-N 2.86Å; I268-S271 PolarHBondContact O-OG 3.17Å
269N69.1Low75.6Confident30 Ų3046.5 Ų46.516%0.1625%0.249CC..Hα-helixtrans-68.7-30.8179.8-72.314000112.4E250 Q252 A265 T266 S271 L272 S273E250-N269 PolarHBondContact O-ND2 3.34Å; Q252-N269 PolarHBondContact NE2-ND2 3.02Å; A265-N269 PolarHBondContact O-N 2.96Å; A265-N269 VanDerWaalsContact O-N 3.13Å; T266-N269 PolarHBondContact O-N 3.05Å; N269-S271 VanDerWaalsContact C-N 3.28Å; N269-S271 PolarHBondContact O-N 3.26Å; N269-L272 PolarHBondContact O-N 3.35Å; N269-L272 VanDerWaalsContact O-N 3.11Å; N269-S273 WeakPolarHBondContact O-CB 3.46Å; N269-S273 PolarHBondContact O-N 3.44Å; N269-S273 PolarHBondContact O-OG 3.4Å; N269-S273 VanDerWaalsContact O-OG 3.11Å
270L80.3Confident76.5Confident85 Ų8545 Ų4545%0.44523%0.23SC..Hα-helixtrans-49.2-49.4174178.764.2000112E150 T266 K267 I268 L272 S273 A274E150-L270 HydrophobicContact CG-CD2 4.19Å; T266-L270 PolarHBondContact O-N 3.03Å; K267-L270 WeakPolarHBondContact O-CB 3.35Å; K267-L270 PolarHBondContact O-N 3.1Å; I268-L270 VanDerWaalsContact C-N 3.33Å; I268-L270 PolarHBondContact O-N 3.49Å; L270-L272 PolarHBondContact O-N 2.9Å; L270-S273 PolarHBondContact O-N 3.04Å; L270-A274 VanDerWaalsContact O-CB 3.26Å; L270-A274 WeakPolarHBondContact O-CB 3.45Å; L270-A274 PolarHBondContact O-N 2.83Å
271S84.1Confident77.8Confident1 Ų138.4 Ų38.41%0.00720%0.202CC..Hα-helixtrans-65.4-35.2-179.6660000114.3E150 H216 I268 N269 L275E150-S271 WeakPolarHBondContact OE1-CB 3.33Å; H216-S271 PolarHBondContact NE2-OG 3.28Å; I268-S271 PolarHBondContact O-N 2.86Å; I268-S271 PolarHBondContact O-OG 3.17Å; N269-S271 VanDerWaalsContact C-N 3.28Å; N269-S271 PolarHBondContact O-N 3.26Å; S271-L275 WeakPolarHBondContact O-CB 3.41Å; S271-L275 PolarHBondContact O-N 2.81Å; S271-L275 VanDerWaalsContact O-N 3.16Å
272L85.9Confident79.1Confident9 Ų935.8 Ų35.85%0.04720%0.195CC..Hα-helixtrans-80.9-33.5178.1-69.1-178.8000112.5Y95 L246 A247 G248 N269 L270 L275 G276 L297Y95-L272 HydrophobicContact CD2-CD2 4.43Å; Y95-L272 HydrophobicContact CE2-CD2 4.19Å; L246-L272 HydrophobicContact CB-CD2 4.46Å; L246-L272 HydrophobicContact CD1-CD2 4.3Å; A247-L272 HydrophobicContact CB-CD1 4.4Å; G248-L272 WeakPolarHBondContact O-CD1 3.34Å; N269-L272 PolarHBondContact O-N 3.35Å; N269-L272 VanDerWaalsContact O-N 3.11Å; L270-L272 PolarHBondContact O-N 2.9Å; L272-L275 HydrophobicContact CD2-CD2 4.43Å; L272-L275 WeakPolarHBondContact O-CB 3.45Å; L272-L275 PolarHBondContact O-N 2.86Å; L272-G276 PolarHBondContact O-N 3.44Å; L272-L297 HydrophobicContact CD2-CD2 4.43Å
273S84.5Confident80.2Confident66 Ų6634.6 Ų34.646%0.46219%0.19SC..Hα-helixtrans-67-44.1171.2-64.40000111N269 L270 L275 G276 N277N269-S273 WeakPolarHBondContact O-CB 3.46Å; N269-S273 PolarHBondContact O-N 3.44Å; N269-S273 PolarHBondContact O-OG 3.4Å; N269-S273 VanDerWaalsContact O-OG 3.11Å; L270-S273 PolarHBondContact O-N 3.04Å; S273-L275 VanDerWaalsContact C-N 3.3Å; S273-L275 PolarHBondContact O-N 2.95Å; S273-G276 CarbonylContact O-C 3.39Å; S273-G276 WeakPolarHBondContact O-CA 3.46Å; S273-G276 PolarHBondContact O-N 2.78Å; S273-N277 PolarHBondContact O-N 3.06Å; S273-N277 PolarHBondContact O-OD1 2.85Å
274A88.3Confident80.9Confident2 Ų233.1 Ų33.12%0.01719%0.189CC..Hα-helixtrans-56.6-44171.600000111.5L270 G276 N277 V278 D294 T298L270-A274 VanDerWaalsContact O-CB 3.26Å; L270-A274 WeakPolarHBondContact O-CB 3.45Å; L270-A274 PolarHBondContact O-N 2.83Å; A274-G276 VanDerWaalsContact C-N 3.31Å; A274-G276 PolarHBondContact O-N 2.94Å; A274-N277 PolarHBondContact O-N 3.29Å; A274-V278 WeakPolarHBondContact O-CG2 3.39Å; A274-V278 PolarHBondContact O-N 3.2Å; A274-D294 HydrophobicContact CB-CB 3.8Å; A274-T298 HydrophobicContact CB-CG2 4.1Å
275L90.9Very high81.3Confident1 Ų136 Ų361%0.00522%0.222CC..Hα-helixtrans-59.4-41.8173.8-162.772.2000111.4L246 S271 L272 S273 V278 I279 L297 T298 L301 L305 Y333L246-L275 HydrophobicContact CD1-CD2 4.04Å; S271-L275 WeakPolarHBondContact O-CB 3.41Å; S271-L275 PolarHBondContact O-N 2.81Å; S271-L275 VanDerWaalsContact O-N 3.16Å; L272-L275 HydrophobicContact CD2-CD2 4.43Å; L272-L275 WeakPolarHBondContact O-CB 3.45Å; L272-L275 PolarHBondContact O-N 2.86Å; S273-L275 VanDerWaalsContact C-N 3.3Å; S273-L275 PolarHBondContact O-N 2.95Å; L275-V278 PolarHBondContact O-N 2.87Å; L275-I279 WeakPolarHBondContact O-CG1 3.36Å; L275-I279 PolarHBondContact O-N 3.21Å; L275-L297 HydrophobicContact CD2-CD2 4.41Å; L275-T298 HydrophobicContact CB-CG2 4.05Å; L275-T298 HydrophobicContact CD1-CG2 3.81Å; L275-L301 HydrophobicContact CD1-CD1 4.33Å; L275-L305 HydrophobicContact CD1-CD1 3.58Å; L275-Y333 VanDerWaalsContact CB-OH 3.3Å; L275-Y333 WeakPolarHBondContact CB-OH 3.44Å; L275-Y333 WeakPolarHBondContact CD2-OH 3.36Å; L275-Y333 WeakPolarHBondContact CG-OH 3.17Å; L275-Y333 PolarHBondContact O-OH 2.88Å
276G88.5Confident82Confident11 Ų1144.1 Ų44.111%0.11326%0.255CS..Hα-helixtrans-64.6-38.3175.200000114.5L272 S273 A274 I279 S280 Y333L272-G276 PolarHBondContact O-N 3.44Å; S273-G276 CarbonylContact O-C 3.39Å; S273-G276 WeakPolarHBondContact O-CA 3.46Å; S273-G276 PolarHBondContact O-N 2.78Å; A274-G276 VanDerWaalsContact C-N 3.31Å; A274-G276 PolarHBondContact O-N 2.94Å; G276-I279 PolarHBondContact O-N 2.91Å; G276-S280 WeakPolarHBondContact O-CB 3.43Å; G276-S280 PolarHBondContact O-N 3.41Å; G276-S280 PolarHBondContact O-OG 2.87Å; G276-Y333 VanDerWaalsContact CA-CE2 3.42Å; G276-Y333 PolarHBondContact N-OH 2.81Å; G276-Y333 VanDerWaalsContact N-OH 3.13Å
277N87.6Confident82.6Confident88 Ų8843.8 Ų43.847%0.47126%0.255SS..Hα-helixtrans-65.6-44.6175-67.8-10.6000110.9S273 A274 S280 A281 P291S273-N277 PolarHBondContact O-N 3.06Å; S273-N277 PolarHBondContact O-OD1 2.85Å; A274-N277 PolarHBondContact O-N 3.29Å; N277-S280 PolarHBondContact O-N 2.83Å; N277-A281 VanDerWaalsContact O-CB 3.27Å; N277-A281 WeakPolarHBondContact O-CB 3.37Å; N277-A281 PolarHBondContact O-N 2.85Å; N277-P291 HydrophobicContact CB-CG 4.1Å
278V91.6Very high83.2Confident0 Ų046.9 Ų46.90%028%0.282CS..Hα-helixtrans-58.5-48.5174.1164.80000111.4A274 L275 A281 L282 I290 P291 Y292 T298 L305A274-V278 WeakPolarHBondContact O-CG2 3.39Å; A274-V278 PolarHBondContact O-N 3.2Å; L275-V278 PolarHBondContact O-N 2.87Å; V278-A281 PolarHBondContact O-N 2.87Å; V278-L282 HydrophobicContact CG1-CD1 3.83Å; V278-L282 WeakPolarHBondContact O-CB 3.44Å; V278-L282 VanDerWaalsContact O-CG 3.28Å; V278-L282 WeakPolarHBondContact O-CG 3.39Å; V278-L282 PolarHBondContact O-N 3.46Å; V278-I290 HydrophobicContact CB-CG2 4.29Å; V278-I290 HydrophobicContact CG1-CG2 3.91Å; V278-I290 HydrophobicContact CG2-CG2 4.19Å; V278-P291 HydrophobicContact CG2-CG 4.14Å; V278-P291 WeakPolarHBondContact CG2-O 3.37Å; V278-Y292 HydrophobicContact CG1-CD1 3.82Å; V278-Y292 HydrophobicContact CG1-CE1 3.48Å; V278-Y292 VanDerWaalsContact CG1-CE1 3.48Å; V278-Y292 HydrophobicContact CG2-CD1 4.03Å; V278-Y292 HydrophobicContact CG2-CE1 4.46Å; V278-T298 HydrophobicContact CB-CG2 4.41Å; V278-T298 HydrophobicContact CG2-CG2 3.86Å; V278-L305 HydrophobicContact CG1-CB 4.41Å; V278-L305 HydrophobicContact CG1-CD1 4.15Å
279I90.2Very high84.1Confident1 Ų153 Ų531%0.00531%0.309CS..Hα-helixtrans-63.3-44.2179.1-70-173.5000111.6L275 G276 L282 V283 Y333 R336 A337 I340L275-I279 WeakPolarHBondContact O-CG1 3.36Å; L275-I279 PolarHBondContact O-N 3.21Å; G276-I279 PolarHBondContact O-N 2.91Å; I279-L282 PolarHBondContact O-N 3.42Å; I279-V283 VanDerWaalsContact O-CG2 3.25Å; I279-V283 WeakPolarHBondContact O-CG2 3.29Å; I279-V283 PolarHBondContact O-N 3.45Å; I279-Y333 HydrophobicContact CD1-CD1 4.27Å; I279-Y333 HydrophobicContact CD1-CE1 3.45Å; I279-Y333 VanDerWaalsContact CD1-CE1 3.45Å; I279-R336 HydrophobicContact CG2-CB 3.91Å; I279-A337 HydrophobicContact CD1-CB 4.05Å; I279-A337 HydrophobicContact CG2-CB 4.35Å; I279-I340 HydrophobicContact CB-CD1 4.24Å; I279-I340 HydrophobicContact CD1-CD1 4.24Å; I279-I340 HydrophobicContact CG1-CD1 3.76Å; I279-I340 HydrophobicContact CG2-CD1 4.07Å
280S86.9Confident85.1Confident22 Ų2253 Ų5315%0.15431%0.309CS..Hα-helixtrans-66-45.2-179.5-52.90000110.8G276 N277 L282 V283 D284 R336G276-S280 WeakPolarHBondContact O-CB 3.43Å; G276-S280 PolarHBondContact O-N 3.41Å; G276-S280 PolarHBondContact O-OG 2.87Å; N277-S280 PolarHBondContact O-N 2.83Å; S280-L282 VanDerWaalsContact C-N 3.31Å; S280-L282 PolarHBondContact O-N 2.8Å; S280-V283 PolarHBondContact O-N 2.77Å; S280-V283 VanDerWaalsContact O-N 3.13Å; S280-D284 WeakPolarHBondContact O-CB 3.48Å; S280-D284 VanDerWaalsContact O-CG 3.25Å; S280-D284 PolarHBondContact O-N 2.73Å; S280-R336 PolarHBondContact OG-NH1 2.85Å
281A88.3Confident85.6Confident12 Ų1249.9 Ų49.910%0.09929%0.294CS..Hα-helixtrans-61-35.817600000113.5N277 V278 V283 I290N277-A281 VanDerWaalsContact O-CB 3.27Å; N277-A281 WeakPolarHBondContact O-CB 3.37Å; N277-A281 PolarHBondContact O-N 2.85Å; V278-A281 PolarHBondContact O-N 2.87Å; A281-V283 VanDerWaalsContact C-N 3.33Å; A281-I290 HydrophobicContact CB-CD1 3.73Å
282L88.8Confident86Confident44 Ų4451.5 Ų51.523%0.2330%0.3CS..Hα-helixtrans-69.8-27.1176.6-80.1168.4000113.8V278 I279 S280 I290 L305 I340V278-L282 HydrophobicContact CG1-CD1 3.83Å; V278-L282 WeakPolarHBondContact O-CB 3.44Å; V278-L282 VanDerWaalsContact O-CG 3.28Å; V278-L282 WeakPolarHBondContact O-CG 3.39Å; V278-L282 PolarHBondContact O-N 3.46Å; I279-L282 PolarHBondContact O-N 3.42Å; S280-L282 VanDerWaalsContact C-N 3.31Å; S280-L282 PolarHBondContact O-N 2.8Å; L282-I290 HydrophobicContact CD2-CD1 4.06Å; L282-I290 HydrophobicContact CD2-CG1 4.03Å; L282-I290 HydrophobicContact CD2-CG2 4.42Å; L282-I290 HydrophobicContact CG-CD1 4.17Å; L282-I290 HydrophobicContact CG-CG1 4.39Å; L282-I290 HydrophobicContact CG-CG2 4.06Å; L282-L305 HydrophobicContact CD1-CB 3.91Å; L282-I340 HydrophobicContact CB-CG1 4.21Å; L282-I340 HydrophobicContact CD1-CD1 4.35Å; L282-I340 HydrophobicContact CD1-CG1 4.47Å; L282-I340 HydrophobicContact CD1-CG2 4.05Å
283V86.9Confident86.2Confident44 Ų4459.3 Ų59.327%0.26733%0.329SS..Hα-helixtrans-96.2-34.9-174.7174.80000111.9I279 S280 A281 G285 R336 N339 I340I279-V283 VanDerWaalsContact O-CG2 3.25Å; I279-V283 WeakPolarHBondContact O-CG2 3.29Å; I279-V283 PolarHBondContact O-N 3.45Å; S280-V283 PolarHBondContact O-N 2.77Å; S280-V283 VanDerWaalsContact O-N 3.13Å; A281-V283 VanDerWaalsContact C-N 3.33Å; V283-G285 PolarHBondContact O-N 3.12Å; V283-R336 VanDerWaalsContact CG2-O 3.3Å; V283-R336 WeakPolarHBondContact CG2-O 3.41Å; V283-N339 HydrophobicContact CG1-CB 3.85Å; V283-N339 HydrophobicContact CG2-CB 4.04Å; V283-I340 HydrophobicContact CG2-CG1 3.86Å
284D79.6Confident86.3Confident99 Ų9960 Ų6053%0.52933%0.327SS..Hα-helixtrans-64.8-21.2-177.4-75.8-11.3000113.8S280 K286S280-D284 WeakPolarHBondContact O-CB 3.48Å; S280-D284 VanDerWaalsContact O-CG 3.25Å; S280-D284 PolarHBondContact O-N 2.73Å; D284-K286 PolarHBondContact O-N 2.7Å
285G72.5Confident86.5Confident74 Ų7460 Ų6076%0.76333%0.327SS*.SBendtrans66.5-6.2176.700000115.8V283V283-G285 PolarHBondContact O-N 3.12Å
286K78.4Confident86.5Confident182 Ų18263.4 Ų63.479%0.79134%0.342SS*.  trans-89.7-23.4178.4-64.1165.1-170.61690112.9D284 T288D284-K286 PolarHBondContact O-N 2.7Å; K286-T288 PolarHBondContact O-N 3.22Å
287S77.3Confident86.7Confident53 Ų5362.9 Ų62.937%0.37134%0.337SS..  trans-86.8107.3-172.6-59.90000111.4H289S287-H289 VanDerWaalsContact C-N 3.31Å
288T80.2Confident87Confident149 Ų14958.7 Ų58.791%0.91431%0.314SS*.SBendtrans-68.5-30.7175.8-46.90000112.7K286K286-T288 PolarHBondContact O-N 3.22Å
289H86.4Confident87.1Confident140 Ų14061 Ų6165%0.64832%0.323SS*.SBendtrans-109133.2177.8178.9-95.4000110S287S287-H289 VanDerWaalsContact C-N 3.31Å
290I90.2Very high87.2Confident29 Ų2962.6 Ų62.615%0.14933%0.331CS..  trans-109.1125.3176.9-50.9-59.3000108.5V278 A281 L282 Y292V278-I290 HydrophobicContact CB-CG2 4.29Å; V278-I290 HydrophobicContact CG1-CG2 3.91Å; V278-I290 HydrophobicContact CG2-CG2 4.19Å; A281-I290 HydrophobicContact CB-CD1 3.73Å; L282-I290 HydrophobicContact CD2-CD1 4.06Å; L282-I290 HydrophobicContact CD2-CG1 4.03Å; L282-I290 HydrophobicContact CD2-CG2 4.42Å; L282-I290 HydrophobicContact CG-CD1 4.17Å; L282-I290 HydrophobicContact CG-CG1 4.39Å; L282-I290 HydrophobicContact CG-CG2 4.06Å; I290-Y292 HydrophobicContact CB-CD2 4.04Å; I290-Y292 HydrophobicContact CB-CE2 3.53Å; I290-Y292 HydrophobicContact CG1-CE2 4.32Å; I290-Y292 HydrophobicContact CG2-CD1 4.33Å; I290-Y292 HydrophobicContact CG2-CD2 4.03Å; I290-Y292 HydrophobicContact CG2-CE1 3.85Å; I290-Y292 HydrophobicContact CG2-CE2 3.54Å; I290-Y292 HydrophobicContact CG2-CG 4.39Å; I290-Y292 VanDerWaalsContact CG2-CZ 3.41Å; I290-Y292 PolarHBondContact O-N 2.92Å
291P91Very high87.5Confident21 Ų2161.7 Ų61.714%0.13633%0.325CS..  trans-80.956.9-168.833.8-37.7000113.5N277 V278 R293 D294N277-P291 HydrophobicContact CB-CG 4.1Å; V278-P291 HydrophobicContact CG2-CG 4.14Å; V278-P291 WeakPolarHBondContact CG2-O 3.37Å; P291-R293 PolarHBondContact O-N 3.43Å; P291-D294 PolarHBondContact O-N 3.4Å
292Y91.9Very high87.7Confident34 Ų3463.5 Ų63.513%0.13333%0.331CS..G310 helixtrans-63-24.5178.3-61.1-72000113.1V278 I290 D294 T298 R299 Q302 L305V278-Y292 HydrophobicContact CG1-CD1 3.82Å; V278-Y292 HydrophobicContact CG1-CE1 3.48Å; V278-Y292 VanDerWaalsContact CG1-CE1 3.48Å; V278-Y292 HydrophobicContact CG2-CD1 4.03Å; V278-Y292 HydrophobicContact CG2-CE1 4.46Å; I290-Y292 HydrophobicContact CB-CD2 4.04Å; I290-Y292 HydrophobicContact CB-CE2 3.53Å; I290-Y292 HydrophobicContact CG1-CE2 4.32Å; I290-Y292 HydrophobicContact CG2-CD1 4.33Å; I290-Y292 HydrophobicContact CG2-CD2 4.03Å; I290-Y292 HydrophobicContact CG2-CE1 3.85Å; I290-Y292 HydrophobicContact CG2-CE2 3.54Å; I290-Y292 HydrophobicContact CG2-CG 4.39Å; I290-Y292 VanDerWaalsContact CG2-CZ 3.41Å; I290-Y292 PolarHBondContact O-N 2.92Å; Y292-D294 VanDerWaalsContact C-N 3.33Å; Y292-D294 PolarHBondContact O-N 3.22Å; Y292-T298 CarbonylContact O-C 3.59Å; Y292-T298 VanDerWaalsContact O-CB 3.3Å; Y292-T298 WeakPolarHBondContact O-CB 3.4Å; Y292-T298 PolarHBondContact O-OG1 3.37Å; Y292-R299 WeakPolarHBondContact O-CG 3.46Å; Y292-R299 PolarHBondContact O-N 2.89Å; Y292-R299 VanDerWaalsContact O-N 3.11Å; Y292-Q302 HydrophobicContact CD1-CB 3.97Å; Y292-Q302 HydrophobicContact CD1-CG 3.92Å; Y292-Q302 HydrophobicContact CD2-CG 3.77Å; Y292-Q302 HydrophobicContact CE1-CB 4.38Å; Y292-Q302 HydrophobicContact CE1-CG 4.15Å; Y292-Q302 HydrophobicContact CE2-CG 3.98Å; Y292-Q302 HydrophobicContact CG-CB 4.13Å; Y292-Q302 HydrophobicContact CG-CG 3.75Å; Y292-L305 HydrophobicContact CE1-CB 4.5Å; Y292-L305 PolarHBondContact OH-O 2.88Å
293R90Very high87.8Confident173 Ų17364 Ų6465%0.65333%0.334SS*.G310 helixtrans-76-17.2-174.1-68.7-174.9173.8-165.5-3.3114.3P291 S295P291-R293 PolarHBondContact O-N 3.43Å; R293-S295 PolarHBondContact O-N 2.92Å; R293-S295 VanDerWaalsContact O-N 3.12Å
294D86.6Confident88.1Confident80 Ų8062.1 Ų62.143%0.42832%0.323SS..G310 helixtrans-63.6-16.9-176-64.621.2000113.9A274 P291 Y292A274-D294 HydrophobicContact CB-CB 3.8Å; P291-D294 PolarHBondContact O-N 3.4Å; Y292-D294 VanDerWaalsContact C-N 3.33Å; Y292-D294 PolarHBondContact O-N 3.22Å
295S92Very high88.7Confident2 Ų257.4 Ų57.41%0.01430%0.298CS..  trans-149.1155.1168.775.30000113E150 R293 L297 T298 R299E150-S295 WeakPolarHBondContact OE2-CA 3.41Å; E150-S295 WeakPolarHBondContact OE2-CB 3.3Å; R293-S295 PolarHBondContact O-N 2.92Å; R293-S295 VanDerWaalsContact O-N 3.12Å; S295-L297 PolarHBondContact O-N 3.31Å; S295-T298 PolarHBondContact N-OG1 3.06Å; S295-T298 PolarHBondContact O-N 3.32Å; S295-T298 PolarHBondContact O-OG1 3.47Å; S295-T298 PolarHBondContact OG-N 2.97Å; S295-T298 PolarHBondContact OG-OG1 3Å; S295-R299 WeakPolarHBondContact O-CG 3.27Å; S295-R299 PolarHBondContact O-N 3.24Å; S295-R299 VanDerWaalsContact O-N 3.1Å
296K91.9Very high89.4Confident73 Ų7354.9 Ų54.932%0.31727%0.272SS..Hα-helixtrans-60.9-33.2172.7-54.4-65.1176.9168.70111.4I147 E150 I152 L166 L300I147-K296 HydrophobicContact CG2-CB 4.42Å; E150-K296 WeakPolarHBondContact O-CG 3.33Å; E150-K296 WeakPolarHBondContact OE2-CG 3.4Å; E150-K296 PolarHBondContact OE2-N 2.66Å; I152-K296 HydrophobicContact CD1-CB 4.39Å; I152-K296 HydrophobicContact CG1-CB 4.44Å; L166-K296 HydrophobicContact CD1-CB 3.99Å; L166-K296 HydrophobicContact CD1-CD 3.85Å; L166-K296 HydrophobicContact CD1-CG 4.48Å; L166-K296 HydrophobicContact CG-CD 4.36Å; K296-L300 PolarHBondContact O-N 3.31Å
297L93.1Very high89.9Confident0 Ų047.1 Ų47.10%024%0.243CC..Hα-helixtrans-62.8-50.8176178.467.1000111.4I147 H216 I218 L246 L272 L275 S295 R299 L300 L301I147-L297 HydrophobicContact CD1-CB 4.04Å; I147-L297 HydrophobicContact CD1-CD1 4.02Å; H216-L297 HydrophobicContact CB-CD1 4.28Å; I218-L297 HydrophobicContact CD1-CD1 4.26Å; L246-L297 HydrophobicContact CD2-CD1 3.89Å; L246-L297 HydrophobicContact CD2-CD2 3.85Å; L246-L297 HydrophobicContact CD2-CG 4.49Å; L272-L297 HydrophobicContact CD2-CD2 4.43Å; L275-L297 HydrophobicContact CD2-CD2 4.41Å; S295-L297 PolarHBondContact O-N 3.31Å; L297-R299 VanDerWaalsContact C-N 3.33Å; L297-R299 PolarHBondContact O-N 2.74Å; L297-L300 PolarHBondContact O-N 2.82Å; L297-L301 HydrophobicContact CD1-CD1 3.76Å; L297-L301 HydrophobicContact CD1-CG 4.26Å; L297-L301 HydrophobicContact CG-CD1 4.15Å; L297-L301 WeakPolarHBondContact O-CB 3.5Å; L297-L301 WeakPolarHBondContact O-CG 3.39Å; L297-L301 PolarHBondContact O-N 2.72Å
298T93.3Very high90.6Very high0 Ų046.5 Ų46.50%024%0.236CC..Hα-helixtrans-67.5-31.2179.944.30000113A274 L275 V278 Y292 S295 Q302A274-T298 HydrophobicContact CB-CG2 4.1Å; L275-T298 HydrophobicContact CB-CG2 4.05Å; L275-T298 HydrophobicContact CD1-CG2 3.81Å; V278-T298 HydrophobicContact CB-CG2 4.41Å; V278-T298 HydrophobicContact CG2-CG2 3.86Å; Y292-T298 CarbonylContact O-C 3.59Å; Y292-T298 VanDerWaalsContact O-CB 3.3Å; Y292-T298 WeakPolarHBondContact O-CB 3.4Å; Y292-T298 PolarHBondContact O-OG1 3.37Å; S295-T298 PolarHBondContact N-OG1 3.06Å; S295-T298 PolarHBondContact O-N 3.32Å; S295-T298 PolarHBondContact O-OG1 3.47Å; S295-T298 PolarHBondContact OG-N 2.97Å; S295-T298 PolarHBondContact OG-OG1 3Å; T298-Q302 PolarHBondContact O-N 2.81Å
299R93Very high91.2Very high50 Ų5039.4 Ų39.419%0.18919%0.193CC..Hα-helixtrans-66.1-42.9170.6-68.7-169.273179.2-0.5112.2L166 E168 V174 Y292 S295 L297 L301 Q302L166-R299 HydrophobicContact CD1-CB 3.75Å; E168-R299 IonicContact OE2-NH2 3.49Å; E168-R299 PolarHBondContact OE2-NH2 2.92Å; V174-R299 HydrophobicContact CG1-CB 4.34Å; Y292-R299 WeakPolarHBondContact O-CG 3.46Å; Y292-R299 PolarHBondContact O-N 2.89Å; Y292-R299 VanDerWaalsContact O-N 3.11Å; S295-R299 WeakPolarHBondContact O-CG 3.27Å; S295-R299 PolarHBondContact O-N 3.24Å; S295-R299 VanDerWaalsContact O-N 3.1Å; L297-R299 VanDerWaalsContact C-N 3.33Å; L297-R299 PolarHBondContact O-N 2.74Å; R299-L301 VanDerWaalsContact C-N 3.35Å; R299-Q302 VanDerWaalsContact O-CB 3.3Å; R299-Q302 WeakPolarHBondContact O-CB 3.43Å; R299-Q302 PolarHBondContact O-N 3.08Å
300L92.9Very high91.7Very high33 Ų3334.2 Ų34.217%0.17317%0.168CC..Hα-helixtrans-68.7-32.1177-81.7167000113.2I147 I152 L166 V176 I218 K296 L297I147-L300 HydrophobicContact CD1-CD1 3.78Å; I152-L300 HydrophobicContact CD1-CD1 4.03Å; L166-L300 HydrophobicContact CD1-CG 4.31Å; L166-L300 HydrophobicContact CD2-CD1 4.07Å; L166-L300 HydrophobicContact CD2-CD2 3.66Å; L166-L300 HydrophobicContact CD2-CG 3.7Å; V176-L300 HydrophobicContact CG2-CD1 4.39Å; V176-L300 HydrophobicContact CG2-CD2 3.82Å; I218-L300 HydrophobicContact CD1-CD1 4.41Å; K296-L300 PolarHBondContact O-N 3.31Å; L297-L300 PolarHBondContact O-N 2.82Å
301L92.8Very high92Very high3 Ų333.1 Ų33.12%0.01616%0.163CC..THydrogen-bonded Turntrans-93.88.8178.7-60.3-177.3000113.7T91 V244 L275 L297 R299 D303 S304 L305T91-L301 HydrophobicContact CG2-CD2 4.28Å; V244-L301 HydrophobicContact CG2-CD2 4.08Å; L275-L301 HydrophobicContact CD1-CD1 4.33Å; L297-L301 HydrophobicContact CD1-CD1 3.76Å; L297-L301 HydrophobicContact CD1-CG 4.26Å; L297-L301 HydrophobicContact CG-CD1 4.15Å; L297-L301 WeakPolarHBondContact O-CB 3.5Å; L297-L301 WeakPolarHBondContact O-CG 3.39Å; L297-L301 PolarHBondContact O-N 2.72Å; R299-L301 VanDerWaalsContact C-N 3.35Å; L301-D303 VanDerWaalsContact C-N 3.32Å; L301-D303 PolarHBondContact O-N 3.34Å; L301-S304 WeakPolarHBondContact O-CA 3.45Å; L301-S304 VanDerWaalsContact O-CB 3.28Å; L301-S304 WeakPolarHBondContact O-CB 3.49Å; L301-S304 PolarHBondContact O-N 2.92Å; L301-L305 PolarHBondContact O-N 3Å; L301-L305 VanDerWaalsContact O-N 3.14Å
302Q92.3Very high92.3Very high50 Ų5032.1 Ų32.123%0.23416%0.156CC..G310 helixtrans-55.3-42.9-179.2-179.4172.3-44.500112.5Y292 T298 R299 S304 L305Y292-Q302 HydrophobicContact CD1-CB 3.97Å; Y292-Q302 HydrophobicContact CD1-CG 3.92Å; Y292-Q302 HydrophobicContact CD2-CG 3.77Å; Y292-Q302 HydrophobicContact CE1-CB 4.38Å; Y292-Q302 HydrophobicContact CE1-CG 4.15Å; Y292-Q302 HydrophobicContact CE2-CG 3.98Å; Y292-Q302 HydrophobicContact CG-CB 4.13Å; Y292-Q302 HydrophobicContact CG-CG 3.75Å; T298-Q302 PolarHBondContact O-N 2.81Å; R299-Q302 VanDerWaalsContact O-CB 3.3Å; R299-Q302 WeakPolarHBondContact O-CB 3.43Å; R299-Q302 PolarHBondContact O-N 3.08Å; Q302-S304 VanDerWaalsContact C-N 3.26Å; Q302-S304 PolarHBondContact O-N 2.97Å; Q302-L305 PolarHBondContact O-N 2.67Å
303D90.8Very high92.6Very high56 Ų5630.5 Ų30.530%0.29915%0.15SC..G310 helixtrans-70.2-23175.2-75.6-48.9000113.7L301 G307 N308 A309L301-D303 VanDerWaalsContact C-N 3.32Å; L301-D303 PolarHBondContact O-N 3.34Å; D303-G307 CarbonylContact O-C 3.53Å; D303-G307 VanDerWaalsContact O-CA 3.32Å; D303-G307 WeakPolarHBondContact O-CA 3.42Å; D303-N308 CarbonylContact O-C 3.59Å; D303-N308 PolarHBondContact O-N 2.8Å; D303-A309 WeakPolarHBondContact O-CB 3.34Å; D303-A309 PolarHBondContact O-N 3.29Å
304S93.4Very high93Very high3 Ų322.3 Ų22.32%0.02112%0.119CC..G310 helixtrans-81.6-21.1-179.2-51.70000113.1T91 L301 Q302 T311 N342T91-S304 WeakPolarHBondContact CB-OG 3.1Å; T91-S304 PolarHBondContact OG1-OG 3.23Å; L301-S304 WeakPolarHBondContact O-CA 3.45Å; L301-S304 VanDerWaalsContact O-CB 3.28Å; L301-S304 WeakPolarHBondContact O-CB 3.49Å; L301-S304 PolarHBondContact O-N 2.92Å; Q302-S304 VanDerWaalsContact C-N 3.26Å; Q302-S304 PolarHBondContact O-N 2.97Å; S304-T311 WeakPolarHBondContact O-CB 3.49Å; S304-T311 PolarHBondContact O-OG1 3.46Å; S304-N342 PolarHBondContact O-ND2 2.89Å
305L92.3Very high93.5Very high1 Ų118.5 Ų18.51%0.00510%0.099CC..SBendtrans-123.495.6-175.5-60.2175.1000108.6F93 L275 V278 L282 Y292 L301 Q302 G307 I340F93-L305 HydrophobicContact CE1-CD2 4.3Å; F93-L305 HydrophobicContact CZ-CD2 4.44Å; L275-L305 HydrophobicContact CD1-CD1 3.58Å; V278-L305 HydrophobicContact CG1-CB 4.41Å; V278-L305 HydrophobicContact CG1-CD1 4.15Å; L282-L305 HydrophobicContact CD1-CB 3.91Å; Y292-L305 HydrophobicContact CE1-CB 4.5Å; Y292-L305 PolarHBondContact OH-O 2.88Å; L301-L305 PolarHBondContact O-N 3Å; L301-L305 VanDerWaalsContact O-N 3.14Å; Q302-L305 PolarHBondContact O-N 2.67Å; L305-G307 VanDerWaalsContact C-N 3.32Å; L305-G307 PolarHBondContact O-N 3.07Å; L305-I340 HydrophobicContact CD2-CD1 4.09Å
306G87.3Confident93.8Very high21 Ų2118.4 Ų18.422%0.21610%0.098CC..SBendtrans84.1-6.2-177.100000115.7N342G306-N342 WeakPolarHBondContact CA-OD1 3.23Å; G306-N342 PolarHBondContact N-OD1 2.74Å
307G90.2Very high94Very high19 Ų1915 Ų1520%0.1968%0.083CC..SBendtrans-101-150.7-175.100000116.1D303 L305 A309 K343D303-G307 CarbonylContact O-C 3.53Å; D303-G307 VanDerWaalsContact O-CA 3.32Å; D303-G307 WeakPolarHBondContact O-CA 3.42Å; L305-G307 VanDerWaalsContact C-N 3.32Å; L305-G307 PolarHBondContact O-N 3.07Å; G307-A309 PolarHBondContact O-N 3.48Å; G307-K343 PolarHBondContact O-N 2.82Å
308N91.6Very high94Very high39 Ų3915 Ų1521%0.2098%0.083CC..SBendtrans-9166.7-179.1-178.431.5000112.3N89 D303 R345 N347N89-N308 WeakPolarHBondContact CB-O 3.42Å; N89-N308 PolarHBondContact ND2-O 2.94Å; D303-N308 CarbonylContact O-C 3.59Å; D303-N308 PolarHBondContact O-N 2.8Å; N308-R345 PolarHBondContact OD1-N 3.35Å; N308-N347 PolarHBondContact ND2-OD1 3.37Å
309A93.3Very high94.1Very high1 Ų115.1 Ų15.11%0.0088%0.084CC..SBendtrans-154.2155.5168.600000112.1N89 D303 G307 N342N89-A309 HydrophobicContact CB-CB 3.73Å; N89-A309 WeakPolarHBondContact O-CA 3.05Å; D303-A309 WeakPolarHBondContact O-CB 3.34Å; D303-A309 PolarHBondContact O-N 3.29Å; G307-A309 PolarHBondContact O-N 3.48Å; A309-N342 VanDerWaalsContact O-CB 3.25Å; A309-N342 WeakPolarHBondContact O-CB 3.32Å; A309-N342 PolarHBondContact O-ND2 2.88Å
310K96.1Very high94.1Very high31 Ų3112.7 Ų12.714%0.1358%0.075CC..EExtended strand (participates in β ladder)trans-83.8140.4160.1-62.4-170.1-174.7179.90108.2E8 L80 S83 N89 G90 T91 P344E8-K310 WeakPolarHBondContact OE2-CD 3.39Å; E8-K310 WeakPolarHBondContact OE2-CE 3.27Å; E8-K310 WeakPolarHBondContact OE2-CG 3.26Å; L80-K310 HydrophobicContact CD1-CB 3.33Å; S83-K310 PolarHBondContact OG-NZ 3.39Å; N89-K310 PolarHBondContact O-N 2.95Å; G90-K310 CarbonylContact C-O 3.55Å; G90-K310 VanDerWaalsContact CA-O 3.31Å; G90-K310 WeakPolarHBondContact CA-O 3.21Å; T91-K310 PolarHBondContact N-O 3.06Å; K310-P344 HydrophobicContact CG-CB 3.62Å; K310-P344 HydrophobicContact CG-CG 3.9Å
311T96.8Very high94Very high5 Ų512.2 Ų12.23%0.0317%0.074CC..EExtended strand (participates in β ladder)trans-141.8136.3-171.6-58.30000112.1V10 R11 T91 F93 S304 N342V10-T311 HydrophobicContact CG1-CG2 4.07Å; R11-T311 PolarHBondContact N-O 3.3Å; T91-T311 HydrophobicContact CG2-CG2 4.35Å; T91-T311 CarbonylContact O-C 3.55Å; T91-T311 WeakPolarHBondContact O-CA 3.34Å; F93-T311 HydrophobicContact CD1-CG2 3.99Å; F93-T311 HydrophobicContact CE1-CG2 3.68Å; S304-T311 WeakPolarHBondContact O-CB 3.49Å; S304-T311 PolarHBondContact O-OG1 3.46Å; T311-N342 PolarHBondContact OG1-ND2 3.39Å
312V97.9Very high93.7Very high1 Ų118 Ų181%0.00610%0.097CC..EExtended strand (participates in β ladder)trans-120.7120.6175.5179.50000108.8R11 T76 F77 L80 T91 I92 F93 V314R11-V312 HydrophobicContact CB-CG2 4.38Å; R11-V312 CarbonylContact O-C 3.24Å; R11-V312 WeakPolarHBondContact O-CA 3.42Å; T76-V312 HydrophobicContact CG2-CG1 3.65Å; F77-V312 HydrophobicContact CD1-CG1 4.16Å; F77-V312 HydrophobicContact CE1-CG1 3.88Å; L80-V312 HydrophobicContact CB-CG2 4.49Å; L80-V312 HydrophobicContact CD1-CG2 4.35Å; L80-V312 HydrophobicContact CD2-CG2 4.07Å; T91-V312 PolarHBondContact O-N 3.44Å; I92-V312 WeakPolarHBondContact CA-O 3.44Å; F93-V312 PolarHBondContact N-O 2.76Å; V312-V314 HydrophobicContact CG1-CG2 4.44Å
313M97.4Very high93.5Very high0 Ų016.2 Ų16.20%09%0.089CC..EExtended strand (participates in β ladder)trans-93.6132.7166.9178.8-179.417600109.6R11 V12 V13 F93 Y95 A315 Y333 A334 A337R11-M313 PolarHBondContact O-N 3.18Å; V12-M313 HydrophobicContact CG1-CB 4.39Å; V12-M313 HydrophobicContact CG1-CG 4.46Å; V12-M313 HydrophobicContact CG1-SD 4.26Å; V12-M313 HydrophobicContact CG2-CB 4.14Å; V13-M313 PolarHBondContact N-O 2.69Å; F93-M313 HydrophobicContact CD2-CG 4.16Å; F93-M313 HydrophobicContact CE1-CB 3.9Å; F93-M313 HydrophobicContact CE1-CG 4.41Å; F93-M313 HydrophobicContact CE2-CB 3.9Å; F93-M313 HydrophobicContact CE2-CE 4.44Å; F93-M313 HydrophobicContact CE2-CG 3.47Å; F93-M313 VanDerWaalsContact CE2-CG 3.47Å; F93-M313 HydrophobicContact CE2-SD 3.97Å; F93-M313 HydrophobicContact CZ-CB 3.55Å; F93-M313 HydrophobicContact CZ-CG 3.63Å; F93-M313 HydrophobicContact CZ-SD 4.04Å; Y95-M313 HydrophobicContact CD1-CE 3.54Å; Y95-M313 HydrophobicContact CE1-CE 4.4Å; Y95-M313 HydrophobicContact CG-CE 3.78Å; M313-A315 HydrophobicContact CE-CB 4.2Å; M313-Y333 HydrophobicContact CE-CD1 3.73Å; M313-Y333 HydrophobicContact CE-CE1 4.2Å; M313-Y333 HydrophobicContact SD-CD1 4.47Å; M313-A334 HydrophobicContact CE-CB 3.98Å; M313-A334 HydrophobicContact SD-CB 4.3Å; M313-A337 HydrophobicContact SD-CB 3.62Å
314V97.9Very high93.4Very high0 Ų013.8 Ų13.80%08%0.076CC..EExtended strand (participates in β ladder)trans-109.5110.1168.6-171.70000109.2V13 R15 F77 I92 F93 A94 Y95 T105 V312 N316V13-V314 HydrophobicContact CG2-CB 4.32Å; V13-V314 HydrophobicContact CG2-CG1 4.18Å; V13-V314 HydrophobicContact CG2-CG2 3.97Å; V13-V314 WeakPolarHBondContact O-CA 3.21Å; R15-V314 HydrophobicContact CB-CG1 4.4Å; F77-V314 HydrophobicContact CE1-CG2 3.57Å; F77-V314 HydrophobicContact CZ-CG2 3.55Å; I92-V314 HydrophobicContact CG2-CG2 4.33Å; F93-V314 PolarHBondContact O-N 2.78Å; A94-V314 WeakPolarHBondContact CA-O 3.43Å; Y95-V314 PolarHBondContact N-O 2.65Å; T105-V314 HydrophobicContact CG2-CG1 4.18Å; V312-V314 HydrophobicContact CG1-CG2 4.44Å; V314-N316 PolarHBondContact O-N 3.07Å
315A97.7Very high93Very high0 Ų017.2 Ų17.20%09%0.092CC..EExtended strand (participates in β ladder)trans-88.2102.917600000109.9V13 V14 R15 M313 T330 A334V13-A315 PolarHBondContact O-N 2.65Å; V14-A315 CarbonylContact C-O 3.6Å; V14-A315 WeakPolarHBondContact CA-O 3.27Å; V14-A315 HydrophobicContact CG2-CB 4.13Å; R15-A315 PolarHBondContact N-O 2.84Å; M313-A315 HydrophobicContact CE-CB 4.2Å; A315-T330 HydrophobicContact CB-CG2 4.05Å; A315-A334 HydrophobicContact CB-CB 3.8Å
316N97.1Very high92.8Very high1 Ų117.3 Ų17.31%0.0059%0.092CC..EExtended strand (participates in β ladder)trans-87.5123.9178.8-69.4109.8000111R15 Y95 T100 K102 T105 V314R15-N316 WeakPolarHBondContact O-CA 3.29Å; Y95-N316 PolarHBondContact O-N 2.97Å; T100-N316 WeakPolarHBondContact CB-O 3.36Å; T100-N316 WeakPolarHBondContact OG1-CB 3.31Å; T100-N316 PolarHBondContact OG1-O 2.9Å; K102-N316 WeakPolarHBondContact CA-OD1 3.4Å; K102-N316 HydrophobicContact CG-CB 4.16Å; T105-N316 PolarHBondContact OG1-ND2 2.82Å; V314-N316 PolarHBondContact O-N 3.07Å
317I96.5Very high93.1Very high1 Ų116.4 Ų16.41%0.0058%0.082CC..EExtended strand (participates in β ladder)trans-128.3154.3-178.162.9171.8000112.9V14 R15 C16 R17 V32 V41 T327 T330 L331V14-I317 HydrophobicContact CG1-CD1 3.61Å; V14-I317 HydrophobicContact CG1-CG1 3.87Å; R15-I317 PolarHBondContact O-N 2.72Å; C16-I317 HydrophobicContact CB-CD1 4.2Å; C16-I317 HydrophobicContact CB-CG1 3.91Å; R17-I317 PolarHBondContact N-O 2.9Å; V32-I317 HydrophobicContact CG1-CD1 3.85Å; V41-I317 HydrophobicContact CG1-CD1 4.01Å; I317-T327 HydrophobicContact CB-CG2 3.98Å; I317-T327 HydrophobicContact CD1-CG2 4.06Å; I317-T327 HydrophobicContact CG2-CG2 4.08Å; I317-T330 HydrophobicContact CG2-CG2 3.67Å; I317-L331 HydrophobicContact CD1-CD1 4.48Å; I317-L331 HydrophobicContact CD1-CD2 4.37Å
318G94.1Very high93.1Very high0 Ų016.2 Ų16.20%08%0.077CC..  trans-96.4149.317300000111.7V32V32-G318 WeakPolarHBondContact CG2-O 3.41Å
319P94.4Very high93Very high2 Ų215.7 Ų15.71%0.0138%0.075CC..  trans-84-12.2-178.332.2-35.2000114.5R17 M19 K30 V31R17-P319 WeakPolarHBondContact O-CD 3.3Å; R17-P319 WeakPolarHBondContact O-CG 3.47Å; M19-P319 HydrophobicContact CB-CG 3.84Å; M19-P319 HydrophobicContact CG-CG 4.46Å; K30-P319 WeakPolarHBondContact CA-O 3.45Å; K30-P319 HydrophobicContact CG-CB 4.27Å; V31-P319 PolarHBondContact N-O 3.17Å
320A93.1Very high93Very high0 Ų015.7 Ų15.70%08%0.075CC..BIsolated β-bridgetrans-85.7141.9-165.600000114.1M19 E23 Y28 E29 Y322 N323M19-A320 HydrophobicContact CE-CB 3.79Å; E23-A320 HydrophobicContact CB-CB 4.15Å; E23-A320 HydrophobicContact CG-CB 3.79Å; Y28-A320 HydrophobicContact CD2-CB 4.46Å; E29-A320 CarbonylContact O-C 3.55Å; E29-A320 WeakPolarHBondContact O-CA 3.29Å; A320-Y322 PolarHBondContact O-N 3.02Å; A320-Y322 VanDerWaalsContact O-N 3.16Å; A320-N323 PolarHBondContact O-N 3.49Å
321S90.5Very high92.9Very high23 Ų2314.2 Ų14.216%0.1617%0.069CC..G310 helixtrans-52.3-36179.859.40000114.3E29 N323 V324E29-S321 PolarHBondContact N-OG 2.98Å; E29-S321 PolarHBondContact O-N 3.16Å; S321-N323 PolarHBondContact O-N 3.38Å; S321-V324 WeakPolarHBondContact O-CB 3.47Å; S321-V324 VanDerWaalsContact O-CG1 3.31Å; S321-V324 WeakPolarHBondContact O-CG1 3.4Å; S321-V324 PolarHBondContact O-N 2.99Å
322Y87.3Confident92.6Very high124 Ų12415.5 Ų15.549%0.4867%0.073SC..G310 helixtrans-58-32176.7-179.7-101.8000113.7Y28 A320Y28-Y322 HydrophobicContact CD2-CG 4.46Å; Y28-Y322 HydrophobicContact CE1-CD2 4.23Å; Y28-Y322 HydrophobicContact CE1-CG 4.37Å; Y28-Y322 HydrophobicContact CE2-CD1 4.36Å; Y28-Y322 HydrophobicContact CE2-CD2 4.28Å; Y28-Y322 AromaticContact CE2-CG 3.81Å; Y28-Y322 HydrophobicContact CE2-CG 3.81Å; Y28-Y322 AromaticContact CZ-CD2 3.76Å; Y28-Y322 AromaticContact CZ-CG 3.77Å; Y28-Y322 WeakPolarHBondContact OH-CD2 3.15Å; A320-Y322 PolarHBondContact O-N 3.02Å; A320-Y322 VanDerWaalsContact O-N 3.16Å
323N87.1Confident92.2Very high13 Ų1316.5 Ų16.57%0.078%0.077CC..G310 helixtrans-102.116.2-176.2-65.5-46000113.1E23 Q97 A320 S321 E325 E326 T327E23-N323 PolarHBondContact OE1-ND2 3.43Å; Q97-N323 PolarHBondContact NE2-OD1 3.03Å; Q97-N323 VanDerWaalsContact OE1-CG 3.23Å; Q97-N323 PolarHBondContact OE1-OD1 3.28Å; A320-N323 PolarHBondContact O-N 3.49Å; S321-N323 PolarHBondContact O-N 3.38Å; N323-E325 VanDerWaalsContact C-N 3.34Å; N323-E325 PolarHBondContact O-N 3.14Å; N323-E326 PolarHBondContact O-N 2.77Å; N323-T327 WeakPolarHBondContact O-CB 3.31Å; N323-T327 PolarHBondContact O-N 3.05Å; N323-T327 PolarHBondContact O-OG1 3.01Å
324V89.6Confident92.1Very high5 Ų516.5 Ų16.53%0.038%0.077CC..Hα-helixtrans-59.8-40.4-174.368.70000113.1V31 V43 P46 S321 T327 L328V31-V324 HydrophobicContact CG2-CB 4.24Å; V31-V324 HydrophobicContact CG2-CG2 4.16Å; V43-V324 HydrophobicContact CG1-CG2 3.71Å; P46-V324 HydrophobicContact CG-CG1 4.22Å; S321-V324 WeakPolarHBondContact O-CB 3.47Å; S321-V324 VanDerWaalsContact O-CG1 3.31Å; S321-V324 WeakPolarHBondContact O-CG1 3.4Å; S321-V324 PolarHBondContact O-N 2.99Å; V324-T327 WeakPolarHBondContact O-CB 3.47Å; V324-T327 PolarHBondContact O-N 2.84Å; V324-L328 HydrophobicContact CG2-CD1 4.38Å; V324-L328 WeakPolarHBondContact O-CG 3.19Å; V324-L328 PolarHBondContact O-N 3.39Å
325E85.7Confident91.8Very high74 Ų7418.3 Ų18.335%0.3469%0.087SC..Hα-helixtrans-61.6-54.5179-66.2164.7-168.200111.2R47 K254 N323 T327 L328 T329R47-E325 IonicContact CZ-OE1 3.24Å; R47-E325 IonicContact NH1-OE1 3.26Å; R47-E325 PolarHBondContact NH1-OE1 2.84Å; R47-E325 IonicContact NH2-OE1 3.56Å; K254-E325 VanDerWaalsContact CE-OE2 3.32Å; K254-E325 WeakPolarHBondContact CE-OE2 3.49Å; K254-E325 IonicContact NZ-OE2 2.66Å; K254-E325 PolarHBondContact NZ-OE2 3.08Å; N323-E325 VanDerWaalsContact C-N 3.34Å; N323-E325 PolarHBondContact O-N 3.14Å; E325-T327 PolarHBondContact O-N 3.43Å; E325-L328 PolarHBondContact O-N 2.9Å; E325-L328 VanDerWaalsContact O-N 3.11Å; E325-T329 PolarHBondContact O-N 2.74Å; E325-T329 PolarHBondContact O-OG1 3.18Å
326E87.9Confident91.4Very high3 Ų322.7 Ų22.71%0.01410%0.103CC..Hα-helixtrans-64.1-31.5179.8-52.4-57.2149.500111.8Q97 E250 K254 N323 T330Q97-E326 HydrophobicContact CB-CB 4.14Å; Q97-E326 HydrophobicContact CG-CB 4.2Å; Q97-E326 HydrophobicContact CG-CG 4.24Å; E250-E326 WeakPolarHBondContact CA-OE2 3.09Å; K254-E326 WeakPolarHBondContact CD-OE1 3.34Å; K254-E326 WeakPolarHBondContact CE-OE1 3.45Å; K254-E326 IonicContact NZ-OE1 2.6Å; K254-E326 PolarHBondContact NZ-OE1 3.2Å; N323-E326 PolarHBondContact O-N 2.77Å; E326-T330 VanDerWaalsContact O-CB 3.29Å; E326-T330 WeakPolarHBondContact O-CB 3.26Å; E326-T330 PolarHBondContact O-N 2.75Å; E326-T330 PolarHBondContact O-OG1 2.75Å
327T92.2Very high91.2Very high2 Ų222.7 Ų22.71%0.01210%0.103CC..Hα-helixtrans-66.7-44.2174.3-620000111V32 V43 I317 N323 V324 E325 T330 L331V32-T327 HydrophobicContact CG2-CG2 3.97Å; V43-T327 HydrophobicContact CG2-CG2 4.23Å; I317-T327 HydrophobicContact CB-CG2 3.98Å; I317-T327 HydrophobicContact CD1-CG2 4.06Å; I317-T327 HydrophobicContact CG2-CG2 4.08Å; N323-T327 WeakPolarHBondContact O-CB 3.31Å; N323-T327 PolarHBondContact O-N 3.05Å; N323-T327 PolarHBondContact O-OG1 3.01Å; V324-T327 WeakPolarHBondContact O-CB 3.47Å; V324-T327 PolarHBondContact O-N 2.84Å; E325-T327 PolarHBondContact O-N 3.43Å; T327-T330 PolarHBondContact O-N 2.85Å; T327-L331 HydrophobicContact CG2-CD1 3.97Å; T327-L331 WeakPolarHBondContact O-CB 3.42Å; T327-L331 VanDerWaalsContact O-CG 3.25Å; T327-L331 WeakPolarHBondContact O-CG 3.34Å; T327-L331 PolarHBondContact O-N 2.84Å
328L90.6Very high91.1Very high15 Ų1525.1 Ų25.18%0.07911%0.114CC..Hα-helixtrans-64.9-44.3174.8-73.1172.6000111.7V43 K55 F57 V324 E325 T330 L331 R332V43-L328 HydrophobicContact CB-CD2 3.92Å; V43-L328 HydrophobicContact CG1-CD2 3.94Å; V43-L328 HydrophobicContact CG1-CG 4.19Å; V43-L328 HydrophobicContact CG2-CD2 4.37Å; K55-L328 HydrophobicContact CB-CD2 4.11Å; K55-L328 HydrophobicContact CD-CD1 4.41Å; K55-L328 HydrophobicContact CD-CD2 4.09Å; F57-L328 HydrophobicContact CE2-CD2 4.1Å; F57-L328 HydrophobicContact CZ-CD2 4.37Å; V324-L328 HydrophobicContact CG2-CD1 4.38Å; V324-L328 WeakPolarHBondContact O-CG 3.19Å; V324-L328 PolarHBondContact O-N 3.39Å; E325-L328 PolarHBondContact O-N 2.9Å; E325-L328 VanDerWaalsContact O-N 3.11Å; L328-T330 VanDerWaalsContact C-N 3.33Å; L328-T330 PolarHBondContact O-N 2.97Å; L328-L331 PolarHBondContact O-N 3.01Å; L328-R332 WeakPolarHBondContact O-CB 3.2Å; L328-R332 WeakPolarHBondContact O-CG 3.31Å; L328-R332 PolarHBondContact O-N 2.71Å
329T89.4Confident90.9Very high29 Ų2928.7 Ų28.718%0.17813%0.133CC..Hα-helixtrans-57.9-46.6174.1-56.40000110.8E325 L331 R332 Y333E325-T329 PolarHBondContact O-N 2.74Å; E325-T329 PolarHBondContact O-OG1 3.18Å; T329-L331 PolarHBondContact O-N 3.05Å; T329-R332 PolarHBondContact O-N 3.22Å; T329-Y333 VanDerWaalsContact O-CB 3.25Å; T329-Y333 WeakPolarHBondContact O-CB 3.29Å; T329-Y333 PolarHBondContact O-N 3.44Å
330T93.4Very high90.8Very high1 Ų128.7 Ų28.71%0.00613%0.132CC..Hα-helixtrans-59.7-42.8177-59.50000112.3Y95 A315 I317 E326 T327 L328 A334Y95-T330 HydrophobicContact CD1-CG2 4.11Å; Y95-T330 HydrophobicContact CE1-CG2 4.25Å; A315-T330 HydrophobicContact CB-CG2 4.05Å; I317-T330 HydrophobicContact CG2-CG2 3.67Å; E326-T330 VanDerWaalsContact O-CB 3.29Å; E326-T330 WeakPolarHBondContact O-CB 3.26Å; E326-T330 PolarHBondContact O-N 2.75Å; E326-T330 PolarHBondContact O-OG1 2.75Å; T327-T330 PolarHBondContact O-N 2.85Å; L328-T330 VanDerWaalsContact C-N 3.33Å; L328-T330 PolarHBondContact O-N 2.97Å; T330-A334 VanDerWaalsContact O-CB 3.26Å; T330-A334 WeakPolarHBondContact O-CB 3.35Å; T330-A334 PolarHBondContact O-N 3.16Å
331L94.3Very high90.8Very high0 Ų033.6 Ų33.60%015%0.154CC..Hα-helixtrans-72.1-40.4179.6-71.2169.3000112.9V14 V41 V43 F57 F59 I317 T327 L328 T329 Y333 A334 N335V14-L331 HydrophobicContact CG1-CD2 3.97Å; V14-L331 HydrophobicContact CG2-CD2 3.77Å; V41-L331 HydrophobicContact CB-CD2 4.31Å; V41-L331 HydrophobicContact CG1-CD1 4.02Å; V41-L331 HydrophobicContact CG1-CD2 4.23Å; V43-L331 HydrophobicContact CG2-CD1 3.41Å; V43-L331 VanDerWaalsContact CG2-CD1 3.41Å; F57-L331 HydrophobicContact CD2-CB 4.01Å; F57-L331 HydrophobicContact CD2-CD1 3.97Å; F57-L331 HydrophobicContact CD2-CG 4.48Å; F57-L331 HydrophobicContact CE1-CB 4.5Å; F57-L331 HydrophobicContact CE2-CB 3.96Å; F57-L331 HydrophobicContact CE2-CD1 4.06Å; F57-L331 HydrophobicContact CG-CB 4.3Å; F57-L331 HydrophobicContact CZ-CB 4.21Å; F59-L331 HydrophobicContact CE2-CD2 3.74Å; F59-L331 HydrophobicContact CZ-CD2 3.76Å; I317-L331 HydrophobicContact CD1-CD1 4.48Å; I317-L331 HydrophobicContact CD1-CD2 4.37Å; T327-L331 HydrophobicContact CG2-CD1 3.97Å; T327-L331 WeakPolarHBondContact O-CB 3.42Å; T327-L331 VanDerWaalsContact O-CG 3.25Å; T327-L331 WeakPolarHBondContact O-CG 3.34Å; T327-L331 PolarHBondContact O-N 2.84Å; L328-L331 PolarHBondContact O-N 3.01Å; T329-L331 PolarHBondContact O-N 3.05Å; L331-Y333 VanDerWaalsContact C-N 3.34Å; L331-A334 PolarHBondContact O-N 3.43Å; L331-N335 VanDerWaalsContact O-CB 3.23Å; L331-N335 WeakPolarHBondContact O-CB 3.38Å; L331-N335 PolarHBondContact O-N 2.93Å
332R90.4Very high90.9Very high32 Ų3232.6 Ų32.612%0.12115%0.147CC..Hα-helixtrans-59.2-46.7172.5-74.1175.2-178.1160.44.4110.7F57 L328 T329 N335 R336 D550 E554F57-R332 HydrophobicContact CE1-CG 4.37Å; F57-R332 HydrophobicContact CZ-CG 4.4Å; L328-R332 WeakPolarHBondContact O-CB 3.2Å; L328-R332 WeakPolarHBondContact O-CG 3.31Å; L328-R332 PolarHBondContact O-N 2.71Å; T329-R332 PolarHBondContact O-N 3.22Å; R332-N335 PolarHBondContact O-N 2.94Å; R332-R336 PolarHBondContact O-N 2.86Å; R332-D550 IonicContact CZ-OD2 2.79Å; R332-D550 IonicContact NH2-OD2 3.83Å; R332-D550 PolarHBondContact NH2-OD2 2.85Å; R332-E554 IonicContact CZ-OE2 2.91Å; R332-E554 IonicContact NH1-OE1 2.8Å; R332-E554 IonicContact NH1-OE2 2.68Å; R332-E554 PolarHBondContact NH1-OE2 2.87Å
333Y90.2Very high91.1Very high21 Ų2132.3 Ų32.38%0.08215%0.148CC..Hα-helixtrans-60-49.8178.3-166-81.7000111.8Y95 L275 G276 I279 M313 T329 L331 N335 R336 A337Y95-Y333 HydrophobicContact CD1-CD1 4.14Å; Y95-Y333 HydrophobicContact CD1-CE1 4.47Å; Y95-Y333 HydrophobicContact CD2-CE1 4.18Å; Y95-Y333 AromaticContact CE1-CD1 3.78Å; Y95-Y333 HydrophobicContact CE1-CD1 3.78Å; Y95-Y333 HydrophobicContact CE1-CD2 4.48Å; Y95-Y333 HydrophobicContact CE1-CE1 4.22Å; Y95-Y333 AromaticContact CE1-CG 3.92Å; Y95-Y333 HydrophobicContact CE1-CG 3.92Å; Y95-Y333 HydrophobicContact CE2-CD1 4.29Å; Y95-Y333 AromaticContact CE2-CE1 3.9Å; Y95-Y333 HydrophobicContact CE2-CE1 3.9Å; Y95-Y333 HydrophobicContact CE2-CE2 4.33Å; Y95-Y333 AromaticContact CE2-CZ 3.93Å; Y95-Y333 HydrophobicContact CG-CE1 4.47Å; Y95-Y333 AromaticContact CZ-CD1 3.86Å; Y95-Y333 AromaticContact CZ-CE1 3.93Å; Y95-Y333 AromaticContact CZ-CG 3.9Å; L275-Y333 VanDerWaalsContact CB-OH 3.3Å; L275-Y333 WeakPolarHBondContact CB-OH 3.44Å; L275-Y333 WeakPolarHBondContact CD2-OH 3.36Å; L275-Y333 WeakPolarHBondContact CG-OH 3.17Å; L275-Y333 PolarHBondContact O-OH 2.88Å; G276-Y333 VanDerWaalsContact CA-CE2 3.42Å; G276-Y333 PolarHBondContact N-OH 2.81Å; G276-Y333 VanDerWaalsContact N-OH 3.13Å; I279-Y333 HydrophobicContact CD1-CD1 4.27Å; I279-Y333 HydrophobicContact CD1-CE1 3.45Å; I279-Y333 VanDerWaalsContact CD1-CE1 3.45Å; M313-Y333 HydrophobicContact CE-CD1 3.73Å; M313-Y333 HydrophobicContact CE-CE1 4.2Å; M313-Y333 HydrophobicContact SD-CD1 4.47Å; T329-Y333 VanDerWaalsContact O-CB 3.25Å; T329-Y333 WeakPolarHBondContact O-CB 3.29Å; T329-Y333 PolarHBondContact O-N 3.44Å; L331-Y333 VanDerWaalsContact C-N 3.34Å; Y333-N335 VanDerWaalsContact C-N 3.32Å; Y333-N335 PolarHBondContact O-N 2.96Å; Y333-R336 PolarHBondContact O-N 2.84Å; Y333-A337 PolarHBondContact O-N 3.06Å
334A94.2Very high91.3Very high0 Ų032.7 Ų32.70%015%0.151CC..Hα-helixtrans-58.7-41174.500000112.4V12 F59 M313 A315 T330 L331 R336 A337 K338V12-A334 HydrophobicContact CG1-CB 3.72Å; F59-A334 HydrophobicContact CE1-CB 3.66Å; F59-A334 HydrophobicContact CZ-CB 4.2Å; M313-A334 HydrophobicContact CE-CB 3.98Å; M313-A334 HydrophobicContact SD-CB 4.3Å; A315-A334 HydrophobicContact CB-CB 3.8Å; T330-A334 VanDerWaalsContact O-CB 3.26Å; T330-A334 WeakPolarHBondContact O-CB 3.35Å; T330-A334 PolarHBondContact O-N 3.16Å; L331-A334 PolarHBondContact O-N 3.43Å; A334-R336 VanDerWaalsContact C-N 3.34Å; A334-R336 PolarHBondContact O-N 2.86Å; A334-A337 PolarHBondContact O-N 2.9Å; A334-K338 PolarHBondContact O-N 3.38Å
335N91.9Very high91.4Very high39 Ų3939 Ų3921%0.20917%0.174CC..Hα-helixtrans-68.9-29.5179.6-171.852.9000113F57 F59 L331 R332 Y333 K338 N339F57-N335 HydrophobicContact CD1-CB 4.19Å; F59-N335 HydrophobicContact CE1-CB 4.3Å; F59-N335 HydrophobicContact CZ-CB 4.49Å; L331-N335 VanDerWaalsContact O-CB 3.23Å; L331-N335 WeakPolarHBondContact O-CB 3.38Å; L331-N335 PolarHBondContact O-N 2.93Å; R332-N335 PolarHBondContact O-N 2.94Å; Y333-N335 VanDerWaalsContact C-N 3.32Å; Y333-N335 PolarHBondContact O-N 2.96Å; N335-K338 WeakPolarHBondContact OD1-CE 3.4Å; N335-K338 PolarHBondContact OD1-NZ 2.84Å; N335-N339 PolarHBondContact O-ND2 3.01Å
336R90.6Very high91.6Very high91 Ų9137.7 Ų37.734%0.34317%0.171SC..Hα-helixtrans-70.1-50.1167.2-64.8-179.3-163.4164.89.4110.4I279 S280 V283 R332 Y333 A334 K338 N339 L551I279-R336 HydrophobicContact CG2-CB 3.91Å; S280-R336 PolarHBondContact OG-NH1 2.85Å; V283-R336 VanDerWaalsContact CG2-O 3.3Å; V283-R336 WeakPolarHBondContact CG2-O 3.41Å; R332-R336 PolarHBondContact O-N 2.86Å; Y333-R336 PolarHBondContact O-N 2.84Å; A334-R336 VanDerWaalsContact C-N 3.34Å; A334-R336 PolarHBondContact O-N 2.86Å; R336-K338 VanDerWaalsContact C-N 3.25Å; R336-K338 PolarHBondContact O-N 2.87Å; R336-K338 VanDerWaalsContact O-N 3.13Å; R336-N339 WeakPolarHBondContact O-CB 3.42Å; R336-N339 PolarHBondContact O-N 2.82Å; R336-L551 VanDerWaalsContact NH2-CD2 3.32Å
337A92.9Very high91.6Very high1 Ų139.2 Ų39.21%0.00818%0.18CC..Hα-helixtrans-53.4-37-174.800000114.1V12 I279 M313 Y333 A334 N339 I340V12-A337 HydrophobicContact CG2-CB 4.1Å; I279-A337 HydrophobicContact CD1-CB 4.05Å; I279-A337 HydrophobicContact CG2-CB 4.35Å; M313-A337 HydrophobicContact SD-CB 3.62Å; Y333-A337 PolarHBondContact O-N 3.06Å; A334-A337 PolarHBondContact O-N 2.9Å; A337-N339 PolarHBondContact O-N 3.49Å; A337-N339 VanDerWaalsContact O-N 3.08Å; A337-I340 HydrophobicContact CB-CD1 4.41Å; A337-I340 WeakPolarHBondContact O-CB 3.49Å; A337-I340 VanDerWaalsContact O-CG1 3.28Å; A337-I340 WeakPolarHBondContact O-CG1 3.24Å; A337-I340 PolarHBondContact O-N 2.87Å; A337-I340 VanDerWaalsContact O-N 3.1Å
338K92.4Very high90.9Very high53 Ų5345.1 Ų45.123%0.2321%0.207CC..THydrogen-bonded Turntrans-62.1-18.2-179.887.7-167-169.6-168.60114.5V10 V12 T58 A334 N335 R336V10-K338 WeakPolarHBondContact O-CA 3.43Å; V12-K338 HydrophobicContact CB-CB 4.04Å; V12-K338 HydrophobicContact CG2-CB 3.58Å; T58-K338 PolarHBondContact O-NZ 2.92Å; A334-K338 PolarHBondContact O-N 3.38Å; N335-K338 WeakPolarHBondContact OD1-CE 3.4Å; N335-K338 PolarHBondContact OD1-NZ 2.84Å; R336-K338 VanDerWaalsContact C-N 3.25Å; R336-K338 PolarHBondContact O-N 2.87Å; R336-K338 VanDerWaalsContact O-N 3.13Å
339N91.3Very high89.7Confident75 Ų7548.3 Ų48.340%0.40122%0.224SC..THydrogen-bonded Turntrans-88.4-12.4-179.2-61-41.8000113V283 N335 R336 A337 K341V283-N339 HydrophobicContact CG1-CB 3.85Å; V283-N339 HydrophobicContact CG2-CB 4.04Å; N335-N339 PolarHBondContact O-ND2 3.01Å; R336-N339 WeakPolarHBondContact O-CB 3.42Å; R336-N339 PolarHBondContact O-N 2.82Å; A337-N339 PolarHBondContact O-N 3.49Å; A337-N339 VanDerWaalsContact O-N 3.08Å; N339-K341 VanDerWaalsContact O-CE 3.31Å; N339-K341 WeakPolarHBondContact O-CE 3.19Å
340I92.6Very high88.2Confident1 Ų150.4 Ų50.41%0.00524%0.238CC..  trans-61.5135.2176.7-59.7168.7000109.6S9 V10 I279 L282 V283 L305 A337S9-I340 CarbonylContact C-O 3.19Å; S9-I340 VanDerWaalsContact CA-O 3.28Å; S9-I340 WeakPolarHBondContact CA-O 3.42Å; V10-I340 HydrophobicContact CB-CB 4.28Å; V10-I340 HydrophobicContact CG2-CB 3.72Å; V10-I340 HydrophobicContact CG2-CD1 4.48Å; V10-I340 HydrophobicContact CG2-CG2 3.75Å; V10-I340 PolarHBondContact N-O 2.88Å; I279-I340 HydrophobicContact CB-CD1 4.24Å; I279-I340 HydrophobicContact CD1-CD1 4.24Å; I279-I340 HydrophobicContact CG1-CD1 3.76Å; I279-I340 HydrophobicContact CG2-CD1 4.07Å; L282-I340 HydrophobicContact CB-CG1 4.21Å; L282-I340 HydrophobicContact CD1-CD1 4.35Å; L282-I340 HydrophobicContact CD1-CG1 4.47Å; L282-I340 HydrophobicContact CD1-CG2 4.05Å; V283-I340 HydrophobicContact CG2-CG1 3.86Å; L305-I340 HydrophobicContact CD2-CD1 4.09Å; A337-I340 HydrophobicContact CB-CD1 4.41Å; A337-I340 WeakPolarHBondContact O-CB 3.49Å; A337-I340 VanDerWaalsContact O-CG1 3.28Å; A337-I340 WeakPolarHBondContact O-CG1 3.24Å; A337-I340 PolarHBondContact O-N 2.87Å; A337-I340 VanDerWaalsContact O-N 3.1Å
341K92.1Very high86.5Confident104 Ų10457.3 Ų57.345%0.45227%0.268SS..EExtended strand (participates in β ladder)trans-111.2106.8-178.7-56.1-57.4174.2-176.90111.1S9 N339S9-K341 PolarHBondContact OG-NZ 3.4Å; N339-K341 VanDerWaalsContact O-CE 3.31Å; N339-K341 WeakPolarHBondContact O-CE 3.19Å
342N93.2Very high84.8Confident2 Ų261.9 Ų61.91%0.01129%0.292CS..EExtended strand (participates in β ladder)trans-85.8164174.2-68.612.9000111S7 E8 S304 G306 A309 T311 P344S7-N342 VanDerWaalsContact CA-O 3.31Å; S7-N342 WeakPolarHBondContact CA-O 3.42Å; E8-N342 PolarHBondContact N-O 3.33Å; E8-N342 PolarHBondContact O-N 2.92Å; S304-N342 PolarHBondContact O-ND2 2.89Å; G306-N342 WeakPolarHBondContact CA-OD1 3.23Å; G306-N342 PolarHBondContact N-OD1 2.74Å; A309-N342 VanDerWaalsContact O-CB 3.25Å; A309-N342 WeakPolarHBondContact O-CB 3.32Å; A309-N342 PolarHBondContact O-ND2 2.88Å; T311-N342 PolarHBondContact OG1-ND2 3.39Å; N342-P344 VanDerWaalsContact C-CD 3.42Å
343K92.1Very high83.7Confident118 Ų11860.4 Ų60.451%0.51329%0.287SS..  trans-12861.7179.2-66.8167.4-1731570110.4G307G307-K343 PolarHBondContact O-N 2.82Å
344P91.4Very high83.1Confident20 Ų2061.5 Ų61.513%0.1330%0.295CS..  trans-62142.1-176.228.1-36.5000112.1E8 F88 K310 N342E8-P344 HydrophobicContact CB-CG 4.05Å; F88-P344 HydrophobicContact CD1-CB 3.94Å; F88-P344 HydrophobicContact CE1-CB 4.25Å; K310-P344 HydrophobicContact CG-CB 3.62Å; K310-P344 HydrophobicContact CG-CG 3.9Å; N342-P344 VanDerWaalsContact C-CD 3.42Å
345R90.5Very high82.3Confident138 Ų13861.5 Ų61.552%0.52130%0.295SS..  trans-138.4158.5175.6-53-174.2-164.7168.413.6109.5F88 N308F88-R345 WeakPolarHBondContact CD1-O 3.22Å; F88-R345 VanDerWaalsContact CE1-C 3.48Å; N308-R345 PolarHBondContact OD1-N 3.35Å
346V89.8Confident81.7Confident46 Ų4663.5 Ų63.528%0.27930%0.299SS..BIsolated β-bridgetrans-72.8134.1166-172.20000107.6Q86 F88 R237 E348Q86-V346 WeakPolarHBondContact O-CG1 3.39Å; F88-V346 HydrophobicContact CD2-CG2 4.08Å; F88-V346 HydrophobicContact CE1-CG2 4.13Å; F88-V346 HydrophobicContact CE2-CG2 3.58Å; F88-V346 HydrophobicContact CZ-CG2 3.61Å; R237-V346 HydrophobicContact CG-CG1 4.22Å; V346-E348 HydrophobicContact CB-CG 4.06Å; V346-E348 HydrophobicContact CG1-CG 3.55Å
347N87.5Confident81.2Confident36 Ų3664.7 Ų64.719%0.19331%0.308CS..  trans-93.8103.3173.9-43.8-57.7000108.4G87 N89 R237 V238 N308G87-N347 PolarHBondContact O-N 2.72Å; G87-N347 PolarHBondContact O-ND2 3.04Å; N89-N347 PolarHBondContact ND2-ND2 3.21Å; N89-N347 PolarHBondContact OD1-ND2 3.11Å; R237-N347 WeakPolarHBondContact CA-O 3.29Å; V238-N347 PolarHBondContact N-O 3.35Å; V238-N347 WeakPolarHBondContact O-CB 3.37Å; V238-N347 PolarHBondContact O-ND2 2.69Å; N308-N347 PolarHBondContact ND2-OD1 3.37Å
348E78.6Confident80.5Confident125 Ų12566.1 Ų66.158%0.58432%0.315SS*.  trans-109.622.4-174.9-56.3177.4153.600111.7I236 R237 V346 P350I236-E348 CarbonylContact O-C 3.55Å; I236-E348 WeakPolarHBondContact O-CA 3.49Å; R237-E348 HydrophobicContact CG-CG 4.3Å; V346-E348 HydrophobicContact CB-CG 4.06Å; V346-E348 HydrophobicContact CG1-CG 3.55Å; E348-P350 VanDerWaalsContact O-CD 3.23Å; E348-P350 WeakPolarHBondContact O-CD 3.46Å
349D65.8Low79.8Confident82 Ų8265.4 Ų65.444%0.43931%0.312SS..  trans-74.2115.5-173.4-160-43.4000111K351D349-K351 PolarHBondContact O-N 2.85Å; D349-K351 VanDerWaalsContact OD1-CB 3.31Å; D349-K351 WeakPolarHBondContact OD1-CB 3.37Å; D349-K351 WeakPolarHBondContact OD1-CG 3.39Å; D349-K351 PolarHBondContact OD1-N 2.82Å
350P56.5Low79.4Confident73 Ų7366.7 Ų66.747%0.47432%0.316SS..SBendtrans-73.8-13.9-178.231.6-36.5000112.8E348 R356E348-P350 VanDerWaalsContact O-CD 3.23Å; E348-P350 WeakPolarHBondContact O-CD 3.46Å; P350-R356 PolarHBondContact O-NE 2.81Å; P350-R356 PolarHBondContact O-NH2 2.98Å
351K58.1Low78.9Confident147 Ų14768.8 Ų68.864%0.63933%0.326SS*.SBendtrans-75.2-44.1-166.5-67.3179.5-178.3174.60113.5D349 R356D349-K351 PolarHBondContact O-N 2.85Å; D349-K351 VanDerWaalsContact OD1-CB 3.31Å; D349-K351 WeakPolarHBondContact OD1-CB 3.37Å; D349-K351 WeakPolarHBondContact OD1-CG 3.39Å; D349-K351 PolarHBondContact OD1-N 2.82Å; K351-R356 PolarHBondContact O-NH2 2.82Å
352D58.2Low78.4Confident95 Ų9564.5 Ų64.551%0.50831%0.307SS..SBendtrans-102.86.5-168.4-71.2-12.7000114.6L354D352-L354 PolarHBondContact O-N 3.22Å
353A68Low77.9Confident2 Ų267.1 Ų67.12%0.01733%0.329CS..  trans-74.1115.5-179.600000112.3I236 V238 L355 R356 E357I236-A353 HydrophobicContact CB-CB 4.45Å; I236-A353 HydrophobicContact CD1-CB 4.33Å; I236-A353 HydrophobicContact CG2-CB 3.58Å; V238-A353 HydrophobicContact CG2-CB 4.49Å; A353-L355 PolarHBondContact O-N 3.29Å; A353-R356 HydrophobicContact CB-CB 4.47Å; A353-R356 VanDerWaalsContact O-CB 3.3Å; A353-R356 WeakPolarHBondContact O-CB 3.31Å; A353-R356 PolarHBondContact O-N 3.43Å; A353-E357 PolarHBondContact O-N 3.2Å
354L77.4Confident77.6Confident44 Ų4468.7 Ų68.723%0.2333%0.332CS..Hα-helixtrans-60.8-29176.2-177.964.7000112.2L139 E224 D352 R356 E357 F358L139-L354 HydrophobicContact CD2-CB 4.22Å; L139-L354 HydrophobicContact CD2-CD2 4.17Å; L139-L354 HydrophobicContact CD2-CG 4.15Å; E224-L354 PolarHBondContact OE2-N 2.88Å; E224-L354 VanDerWaalsContact OE2-N 3.12Å; D352-L354 PolarHBondContact O-N 3.22Å; L354-R356 PolarHBondContact O-N 3.39Å; L354-E357 HydrophobicContact CD1-CB 4.39Å; L354-E357 WeakPolarHBondContact CD1-OE2 3.36Å; L354-E357 PolarHBondContact O-N 3.47Å; L354-F358 HydrophobicContact CD1-CD1 4.47Å; L354-F358 HydrophobicContact CD1-CE1 4.01Å; L354-F358 HydrophobicContact CD1-CZ 4.13Å; L354-F358 HydrophobicContact CD2-CE2 4.11Å; L354-F358 HydrophobicContact CD2-CZ 3.92Å; L354-F358 HydrophobicContact CG-CD2 4.44Å; L354-F358 HydrophobicContact CG-CE1 4.21Å; L354-F358 HydrophobicContact CG-CE2 4.04Å; L354-F358 HydrophobicContact CG-CZ 3.91Å; L354-F358 PolarHBondContact O-N 3.12Å
355L77.8Confident77.1Confident0 Ų068 Ų680%033%0.327CS..Hα-helixtrans-57.9-38172-172.6159.7000111.2L139 E224 I236 A353 F358 Q359 L467L139-L355 HydrophobicContact CB-CB 4.29Å; L139-L355 HydrophobicContact CB-CD1 3.98Å; L139-L355 HydrophobicContact CB-CG 4.38Å; L139-L355 HydrophobicContact CD2-CB 4.18Å; E224-L355 HydrophobicContact CB-CB 4.07Å; E224-L355 HydrophobicContact CB-CD1 4.02Å; E224-L355 WeakPolarHBondContact OE2-CB 3.29Å; E224-L355 PolarHBondContact OE2-N 2.85Å; I236-L355 HydrophobicContact CD1-CD2 4.36Å; A353-L355 PolarHBondContact O-N 3.29Å; L355-F358 PolarHBondContact O-N 3.28Å; L355-Q359 HydrophobicContact CD2-CG 4.07Å; L355-Q359 WeakPolarHBondContact O-CG 3.1Å; L355-Q359 PolarHBondContact O-N 3.34Å; L355-L467 HydrophobicContact CG-CD2 4.27Å
356R78.8Confident76.7Confident81 Ų8166.2 Ų66.231%0.30632%0.323SS..Hα-helixtrans-67.1-45.5174-170.8171.660.8103.3-2111.4I236 P350 K351 A353 L354 F358 Q359 E360I236-R356 HydrophobicContact CD1-CB 3.69Å; I236-R356 HydrophobicContact CD1-CG 4.26Å; P350-R356 PolarHBondContact O-NE 2.81Å; P350-R356 PolarHBondContact O-NH2 2.98Å; K351-R356 PolarHBondContact O-NH2 2.82Å; A353-R356 HydrophobicContact CB-CB 4.47Å; A353-R356 VanDerWaalsContact O-CB 3.3Å; A353-R356 WeakPolarHBondContact O-CB 3.31Å; A353-R356 PolarHBondContact O-N 3.43Å; L354-R356 PolarHBondContact O-N 3.39Å; R356-F358 VanDerWaalsContact C-N 3.25Å; R356-F358 PolarHBondContact O-N 2.72Å; R356-Q359 PolarHBondContact O-N 3.3Å; R356-Q359 VanDerWaalsContact O-N 3.12Å; R356-E360 WeakPolarHBondContact CD-OE1 3.4Å; R356-E360 HydrophobicContact CG-CG 4.19Å; R356-E360 WeakPolarHBondContact CG-OE1 3.48Å; R356-E360 IonicContact CZ-OE1 2.66Å; R356-E360 IonicContact NE-OE1 3.72Å; R356-E360 IonicContact NH1-OE1 3.99Å; R356-E360 PolarHBondContact NH1-OE1 2.87Å; R356-E360 WeakPolarHBondContact O-CB 3.33Å; R356-E360 WeakPolarHBondContact O-CG 3.32Å; R356-E360 PolarHBondContact O-N 2.9Å
357E80.3Confident76.4Confident115 Ų11565.6 Ų65.654%0.53732%0.323SS..Hα-helixtrans-58.4-39.3175.4-60.7-171.5164.700111.7A353 L354 E361A353-E357 PolarHBondContact O-N 3.2Å; L354-E357 HydrophobicContact CD1-CB 4.39Å; L354-E357 WeakPolarHBondContact CD1-OE2 3.36Å; L354-E357 PolarHBondContact O-N 3.47Å; E357-E361 VanDerWaalsContact O-CB 3.3Å; E357-E361 WeakPolarHBondContact O-CB 3.4Å; E357-E361 PolarHBondContact O-N 2.89Å
358F78Confident76.1Confident32 Ų3268 Ų6814%0.1433%0.333CS..Hα-helixtrans-67.7-42.4173.6-71.1-14.6000112.5L139 L354 L355 R356 I362 K466 L467L139-F358 HydrophobicContact CD1-CD2 4.32Å; L139-F358 HydrophobicContact CD1-CE2 4.02Å; L139-F358 HydrophobicContact CD2-CD2 3.82Å; L139-F358 HydrophobicContact CD2-CE2 3.77Å; L354-F358 HydrophobicContact CD1-CD1 4.47Å; L354-F358 HydrophobicContact CD1-CE1 4.01Å; L354-F358 HydrophobicContact CD1-CZ 4.13Å; L354-F358 HydrophobicContact CD2-CE2 4.11Å; L354-F358 HydrophobicContact CD2-CZ 3.92Å; L354-F358 HydrophobicContact CG-CD2 4.44Å; L354-F358 HydrophobicContact CG-CE1 4.21Å; L354-F358 HydrophobicContact CG-CE2 4.04Å; L354-F358 HydrophobicContact CG-CZ 3.91Å; L354-F358 PolarHBondContact O-N 3.12Å; L355-F358 PolarHBondContact O-N 3.28Å; R356-F358 VanDerWaalsContact C-N 3.25Å; R356-F358 PolarHBondContact O-N 2.72Å; F358-I362 VanDerWaalsContact O-CB 3.24Å; F358-I362 WeakPolarHBondContact O-CB 3.38Å; F358-I362 WeakPolarHBondContact O-CD1 3.46Å; F358-I362 WeakPolarHBondContact O-CG1 3.44Å; F358-I362 PolarHBondContact O-N 2.75Å; F358-K466 HydrophobicContact CE2-CD 4.34Å; F358-K466 HydrophobicContact CZ-CD 4.4Å; F358-L467 HydrophobicContact CB-CD2 4.47Å; F358-L467 HydrophobicContact CD2-CD2 4.38Å
359Q77.6Confident76.1Confident37 Ų3764.3 Ų64.317%0.17332%0.317CS..Hα-helixtrans-62.6-45.5174.7-76.7177.4-1500111.8S226 L355 R356 I362 A363S226-Q359 PolarHBondContact OG-NE2 3.47Å; L355-Q359 HydrophobicContact CD2-CG 4.07Å; L355-Q359 WeakPolarHBondContact O-CG 3.1Å; L355-Q359 PolarHBondContact O-N 3.34Å; R356-Q359 PolarHBondContact O-N 3.3Å; R356-Q359 VanDerWaalsContact O-N 3.12Å; Q359-I362 PolarHBondContact O-N 3.34Å; Q359-A363 WeakPolarHBondContact O-CB 3.43Å; Q359-A363 PolarHBondContact O-N 3.07Å
360E83.1Confident76.6Confident103 Ų10365.9 Ų65.948%0.48132%0.322SS..Hα-helixtrans-64.7-45.9178.5-73.3179.7-166.300112.1R356 A363 R364R356-E360 WeakPolarHBondContact CD-OE1 3.4Å; R356-E360 HydrophobicContact CG-CG 4.19Å; R356-E360 WeakPolarHBondContact CG-OE1 3.48Å; R356-E360 IonicContact CZ-OE1 2.66Å; R356-E360 IonicContact NE-OE1 3.72Å; R356-E360 IonicContact NH1-OE1 3.99Å; R356-E360 PolarHBondContact NH1-OE1 2.87Å; R356-E360 WeakPolarHBondContact O-CB 3.33Å; R356-E360 WeakPolarHBondContact O-CG 3.32Å; R356-E360 PolarHBondContact O-N 2.9Å; E360-A363 PolarHBondContact O-N 2.89Å; E360-R364 VanDerWaalsContact O-CB 3.26Å; E360-R364 WeakPolarHBondContact O-CB 3.38Å; E360-R364 PolarHBondContact O-N 3.06Å
361E81.6Confident77.5Confident45 Ų4570 Ų7021%0.2133%0.332CS..Hα-helixtrans-69.5-36.9176.3179.975.3175.100111.1E357 R364 L365 K459 M463E357-E361 VanDerWaalsContact O-CB 3.3Å; E357-E361 WeakPolarHBondContact O-CB 3.4Å; E357-E361 PolarHBondContact O-N 2.89Å; E361-R364 PolarHBondContact O-N 3.06Å; E361-R364 WeakPolarHBondContact OE2-CD 3.39Å; E361-R364 IonicContact OE2-CZ 2.68Å; E361-R364 IonicContact OE2-NH1 3.82Å; E361-R364 PolarHBondContact OE2-NH1 2.92Å; E361-L365 HydrophobicContact CG-CG 4.36Å; E361-L365 VanDerWaalsContact O-CG 3.28Å; E361-L365 WeakPolarHBondContact O-CG 3.29Å; E361-L365 PolarHBondContact O-N 2.91Å; E361-K459 IonicContact OE1-NZ 2.62Å; E361-K459 PolarHBondContact OE1-NZ 3.41Å; E361-M463 HydrophobicContact CG-CE 3.91Å; E361-M463 HydrophobicContact CG-SD 4.03Å
362I81.4Confident78.1Confident13 Ų1367.9 Ų67.97%0.06732%0.32CS..Hα-helixtrans-59.2-48.7171.1-73164.7000110.4F358 Q359 R364 L365 K366 M463 E464 L467F358-I362 VanDerWaalsContact O-CB 3.24Å; F358-I362 WeakPolarHBondContact O-CB 3.38Å; F358-I362 WeakPolarHBondContact O-CD1 3.46Å; F358-I362 WeakPolarHBondContact O-CG1 3.44Å; F358-I362 PolarHBondContact O-N 2.75Å; Q359-I362 PolarHBondContact O-N 3.34Å; I362-R364 VanDerWaalsContact C-N 3.33Å; I362-R364 PolarHBondContact O-N 3.19Å; I362-L365 PolarHBondContact O-N 3.4Å; I362-K366 HydrophobicContact CG2-CD 4.08Å; I362-K366 HydrophobicContact CG2-CG 4.47Å; I362-K366 WeakPolarHBondContact O-CB 3.33Å; I362-K366 WeakPolarHBondContact O-CG 3.5Å; I362-K366 PolarHBondContact O-N 3.15Å; I362-M463 HydrophobicContact CD1-CB 4.06Å; I362-M463 HydrophobicContact CG1-CB 3.87Å; I362-M463 HydrophobicContact CG1-CE 3.86Å; I362-E464 HydrophobicContact CD1-CG 4.05Å; I362-E464 HydrophobicContact CG1-CG 4.46Å; I362-E464 HydrophobicContact CG2-CG 4.28Å; I362-L467 HydrophobicContact CD1-CD1 3.66Å
363A82.7Confident78.3Confident57 Ų5766 Ų6647%0.47132%0.315SS..Hα-helixtrans-60.5-42.2177.600000111.8Q359 E360 K366 A367Q359-A363 WeakPolarHBondContact O-CB 3.43Å; Q359-A363 PolarHBondContact O-N 3.07Å; E360-A363 PolarHBondContact O-N 2.89Å; A363-K366 PolarHBondContact O-N 3.28Å; A363-A367 WeakPolarHBondContact O-CB 3.33Å; A363-A367 PolarHBondContact O-N 3.45Å
364R85.5Confident77.9Confident151 Ų15169.8 Ų69.857%0.5733%0.334SS*.Hα-helixtrans-63.4-44.3176.7-173.1-169.6-174.5-164.37112.7E360 E361 I362 A367 Q368E360-R364 VanDerWaalsContact O-CB 3.26Å; E360-R364 WeakPolarHBondContact O-CB 3.38Å; E360-R364 PolarHBondContact O-N 3.06Å; E361-R364 PolarHBondContact O-N 3.06Å; E361-R364 WeakPolarHBondContact OE2-CD 3.39Å; E361-R364 IonicContact OE2-CZ 2.68Å; E361-R364 IonicContact OE2-NH1 3.82Å; E361-R364 PolarHBondContact OE2-NH1 2.92Å; I362-R364 VanDerWaalsContact C-N 3.33Å; I362-R364 PolarHBondContact O-N 3.19Å; R364-A367 PolarHBondContact O-N 3.13Å; R364-Q368 WeakPolarHBondContact O-CG 3.45Å; R364-Q368 PolarHBondContact O-N 2.88Å
365L82.7Confident76.9Confident6 Ų669.8 Ų69.83%0.03135%0.345CS..Hα-helixtrans-69.6-37.5177.4-63.1-169.4000111.5E361 I362 Q368 L369 L456 K459 I460 M463E361-L365 HydrophobicContact CG-CG 4.36Å; E361-L365 VanDerWaalsContact O-CG 3.28Å; E361-L365 WeakPolarHBondContact O-CG 3.29Å; E361-L365 PolarHBondContact O-N 2.91Å; I362-L365 PolarHBondContact O-N 3.4Å; L365-Q368 WeakPolarHBondContact O-CB 3.44Å; L365-Q368 PolarHBondContact O-N 2.8Å; L365-L369 PolarHBondContact O-N 3.42Å; L365-L456 HydrophobicContact CB-CD1 3.82Å; L365-L456 HydrophobicContact CD1-CD1 4Å; L365-L456 HydrophobicContact CD2-CD1 3.63Å; L365-L456 HydrophobicContact CG-CD1 3.99Å; L365-K459 HydrophobicContact CD1-CB 4.16Å; L365-K459 HydrophobicContact CD1-CD 3.54Å; L365-K459 HydrophobicContact CD1-CG 3.72Å; L365-I460 HydrophobicContact CB-CD1 3.76Å; L365-I460 HydrophobicContact CB-CG1 3.53Å; L365-I460 HydrophobicContact CD1-CG1 3.96Å; L365-I460 HydrophobicContact CG-CG1 4.43Å; L365-M463 HydrophobicContact CD1-CE 3.33Å; L365-M463 HydrophobicContact CG-CE 4.18Å
366K81.6Confident75.8Confident100 Ų10072.4 Ų72.444%0.43536%0.356SS..Hα-helixtrans-59.5-49.2171.8-76.6-177.6178.3-176.10111.1I362 A363 Q368 L369 E370 I460 E464I362-K366 HydrophobicContact CG2-CD 4.08Å; I362-K366 HydrophobicContact CG2-CG 4.47Å; I362-K366 WeakPolarHBondContact O-CB 3.33Å; I362-K366 WeakPolarHBondContact O-CG 3.5Å; I362-K366 PolarHBondContact O-N 3.15Å; A363-K366 PolarHBondContact O-N 3.28Å; K366-Q368 PolarHBondContact O-N 2.89Å; K366-L369 WeakPolarHBondContact O-CB 3.47Å; K366-L369 PolarHBondContact O-N 2.5Å; K366-L369 VanDerWaalsContact O-N 3.08Å; K366-E370 WeakPolarHBondContact O-CB 3.4Å; K366-E370 PolarHBondContact O-N 3.33Å; K366-I460 HydrophobicContact CG-CD1 4.08Å; K366-I460 HydrophobicContact CG-CG2 4.45Å; K366-E464 WeakPolarHBondContact CE-OE1 3.23Å; K366-E464 IonicContact NZ-OE1 2.65Å; K366-E464 PolarHBondContact NZ-OE1 3.24Å
367A83.5Confident74.7Confident33 Ų3376.3 Ų76.327%0.27337%0.371SS..Hα-helixtrans-62.5-26175.200000113.5A363 R364 K371A363-A367 WeakPolarHBondContact O-CB 3.33Å; A363-A367 PolarHBondContact O-N 3.45Å; R364-A367 PolarHBondContact O-N 3.13Å; A367-K371 WeakPolarHBondContact O-CB 3.33Å; A367-K371 VanDerWaalsContact O-CG 3.23Å; A367-K371 WeakPolarHBondContact O-CG 3.46Å; A367-K371 PolarHBondContact O-N 3.43Å
368Q80.8Confident73.2Confident86 Ų8677.3 Ų77.340%0.40237%0.373SS..Hα-helixtrans-74.2-38.3171.7-76.8179.66.700112.8R364 L365 K366 R372 L456R364-Q368 WeakPolarHBondContact O-CG 3.45Å; R364-Q368 PolarHBondContact O-N 2.88Å; L365-Q368 WeakPolarHBondContact O-CB 3.44Å; L365-Q368 PolarHBondContact O-N 2.8Å; K366-Q368 PolarHBondContact O-N 2.89Å; Q368-R372 WeakPolarHBondContact O-CG 3.46Å; Q368-R372 PolarHBondContact O-N 3.4Å; Q368-L456 HydrophobicContact CB-CD2 3.92Å
369L78.8Confident71.9Confident49 Ų4984.7 Ų84.726%0.25740%0.4SS..Hα-helixtrans-64.1-44.8169.8-78.8178.1000111.1L365 K366 R372 S373 T453 L456 I460L365-L369 PolarHBondContact O-N 3.42Å; K366-L369 WeakPolarHBondContact O-CB 3.47Å; K366-L369 PolarHBondContact O-N 2.5Å; K366-L369 VanDerWaalsContact O-N 3.08Å; L369-R372 CarbonylContact O-C 3.21Å; L369-R372 WeakPolarHBondContact O-CA 3.3Å; L369-R372 WeakPolarHBondContact O-CB 3.17Å; L369-R372 PolarHBondContact O-N 3.28Å; L369-R372 VanDerWaalsContact O-N 3.08Å; L369-S373 PolarHBondContact O-N 3.34Å; L369-T453 HydrophobicContact CD2-CG2 4.38Å; L369-L456 HydrophobicContact CD2-CB 4.14Å; L369-L456 HydrophobicContact CD2-CD2 3.7Å; L369-L456 HydrophobicContact CD2-CG 3.96Å; L369-L456 HydrophobicContact CG-CD2 3.7Å; L369-L456 HydrophobicContact CG-CG 3.87Å; L369-I460 HydrophobicContact CD1-CD1 3.44Å; L369-I460 VanDerWaalsContact CD1-CD1 3.44Å; L369-I460 HydrophobicContact CG-CD1 4.16Å
370E75.8Confident70.6Confident114 Ų11491.3 Ų91.353%0.53342%0.424SS..Hα-helixtrans-65.9-42-177.7-165-173.2-172.200112.2K366 R372 S373 I374K366-E370 WeakPolarHBondContact O-CB 3.4Å; K366-E370 PolarHBondContact O-N 3.33Å; E370-R372 PolarHBondContact O-N 3.15Å; E370-S373 WeakPolarHBondContact CA-OG 3.42Å; E370-S373 PolarHBondContact O-N 3.45Å; E370-S373 VanDerWaalsContact O-N 3.11Å; E370-S373 PolarHBondContact O-OG 3.49Å; E370-I374 HydrophobicContact CG-CD1 3.83Å; E370-I374 HydrophobicContact CG-CG1 4.37Å; E370-I374 WeakPolarHBondContact O-CB 3.08Å; E370-I374 VanDerWaalsContact O-CG1 3.31Å; E370-I374 WeakPolarHBondContact O-CG1 3.2Å; E370-I374 PolarHBondContact O-N 2.75Å
371K76.7Confident68.9Low161 Ų16192 Ų9270%0.743%0.427SS*.Hα-helixtrans-61.4-31.1171.8-75.8171.4-177.7177.30112.5A367 G375A367-K371 WeakPolarHBondContact O-CB 3.33Å; A367-K371 VanDerWaalsContact O-CG 3.23Å; A367-K371 WeakPolarHBondContact O-CG 3.46Å; A367-K371 PolarHBondContact O-N 3.43Å; K371-G375 PolarHBondContact O-N 2.8Å
372R69.9Low67.4Low101 Ų101100.4 Ų100.438%0.38146%0.456SS..Hα-helixtrans-75-33.3173.2-75.6179.3167.2-153.6-3.1112.8Q368 L369 E370Q368-R372 WeakPolarHBondContact O-CG 3.46Å; Q368-R372 PolarHBondContact O-N 3.4Å; L369-R372 CarbonylContact O-C 3.21Å; L369-R372 WeakPolarHBondContact O-CA 3.3Å; L369-R372 WeakPolarHBondContact O-CB 3.17Å; L369-R372 PolarHBondContact O-N 3.28Å; L369-R372 VanDerWaalsContact O-N 3.08Å; E370-R372 PolarHBondContact O-N 3.15Å
373S62.8Low65.9Low56 Ų56109.1 Ų109.139%0.39249%0.489SS..Hα-helixtrans-75.2-43.8174.563.90000112.3L369 E370 G375 K376 R377L369-S373 PolarHBondContact O-N 3.34Å; E370-S373 WeakPolarHBondContact CA-OG 3.42Å; E370-S373 PolarHBondContact O-N 3.45Å; E370-S373 VanDerWaalsContact O-N 3.11Å; E370-S373 PolarHBondContact O-OG 3.49Å; S373-G375 VanDerWaalsContact C-N 3.29Å; S373-G375 PolarHBondContact O-N 3.12Å; S373-K376 WeakPolarHBondContact O-CA 3.37Å; S373-K376 WeakPolarHBondContact O-CB 3.39Å; S373-K376 PolarHBondContact O-N 3.45Å; S373-R377 PolarHBondContact O-N 3.2Å
374I58.4Low64.2Low81 Ų81115.4 Ų115.442%0.41550%0.5SS..Hα-helixtrans-61.1-38.1176.3-67168.5000111.2E370 K376 R377 K378E370-I374 HydrophobicContact CG-CD1 3.83Å; E370-I374 HydrophobicContact CG-CG1 4.37Å; E370-I374 WeakPolarHBondContact O-CB 3.08Å; E370-I374 VanDerWaalsContact O-CG1 3.31Å; E370-I374 WeakPolarHBondContact O-CG1 3.2Å; E370-I374 PolarHBondContact O-N 2.75Å; I374-K376 PolarHBondContact O-N 2.83Å; I374-R377 PolarHBondContact O-N 2.62Å; I374-K378 PolarHBondContact O-N 2.88Å
375G57.5Low62.2Low45 Ų45115.8 Ų115.846%0.46451%0.513SS..Hα-helixtrans-58.8-27.3172.800000113.8K371 S373 R379K371-G375 PolarHBondContact O-N 2.8Å; S373-G375 VanDerWaalsContact C-N 3.29Å; S373-G375 PolarHBondContact O-N 3.12Å; G375-R379 WeakPolarHBondContact O-CB 3.03Å
376K55.1Low60.3Low55 Ų55119.3 Ų119.324%0.23955%0.551CS.*Hα-helixtrans-82.5-44.2173.1-64.5173.5174-177.90112S373 I374 K378 R379 R380 E449S373-K376 WeakPolarHBondContact O-CA 3.37Å; S373-K376 WeakPolarHBondContact O-CB 3.39Å; S373-K376 PolarHBondContact O-N 3.45Å; I374-K376 PolarHBondContact O-N 2.83Å; K376-K378 PolarHBondContact O-N 2.69Å; K376-R379 PolarHBondContact O-N 3.27Å; K376-R380 PolarHBondContact O-N 3.32Å; K376-E449 VanDerWaalsContact CE-OE1 3.28Å; K376-E449 WeakPolarHBondContact CE-OE1 3.39Å; K376-E449 IonicContact NZ-OE1 3.19Å
377R54.5Low58.3Low163 Ų163117.2 Ų117.262%0.61556%0.558SS**Hα-helixtrans-58.5-46.4178.2-162.1163.8171.9148.8-4110.8S373 I374 R379 R380 E381 E395S373-R377 PolarHBondContact O-N 3.2Å; I374-R377 PolarHBondContact O-N 2.62Å; R377-R379 VanDerWaalsContact C-N 3.31Å; R377-R379 PolarHBondContact O-N 2.75Å; R377-R380 WeakPolarHBondContact O-CB 3.37Å; R377-R380 PolarHBondContact O-N 2.84Å; R377-R380 VanDerWaalsContact O-N 3.09Å; R377-E381 PolarHBondContact O-N 3.11Å; R377-E395 IonicContact CZ-OE1 2.72Å; R377-E395 IonicContact NH1-OE1 3.59Å; R377-E395 PolarHBondContact NH1-OE1 2.84Å; R377-E395 IonicContact NH2-OE1 3.35Å; R377-E395 PolarHBondContact NH2-OE1 2.95Å
378K49Very low56.2Low136 Ų136124.9 Ų124.959%0.59159%0.588SS**Hα-helixtrans-63.8-27.1173.6-81-172.4170.9-179.30115.3I374 K376 R382I374-K378 PolarHBondContact O-N 2.88Å; K376-K378 PolarHBondContact O-N 2.69Å; K378-R382 PolarHBondContact O-N 2.86Å
379R51.8Low54.3Low186 Ų186130.1 Ų130.170%0.70261%0.613SS**Hα-helixtrans-82.6-19.9176.1-173.7171.9170.2175.9-5.9112.4G375 K376 R377G375-R379 WeakPolarHBondContact O-CB 3.03Å; K376-R379 PolarHBondContact O-N 3.27Å; R377-R379 VanDerWaalsContact C-N 3.31Å; R377-R379 PolarHBondContact O-N 2.75Å
380R50Low52.2Low177 Ų177136.6 Ų136.667%0.66864%0.642SS**Hα-helixtrans-80.8-43.1170.4-172.2170.3165168.8-7.8110.6K376 R377 R383 R384K376-R380 PolarHBondContact O-N 3.32Å; R377-R380 WeakPolarHBondContact O-CB 3.37Å; R377-R380 PolarHBondContact O-N 2.84Å; R377-R380 VanDerWaalsContact O-N 3.09Å; R380-R383 PolarHBondContact O-N 2.91Å; R380-R383 VanDerWaalsContact O-N 3.13Å; R380-R384 PolarHBondContact O-N 3.19Å
381E47.3Very low50.3Low117 Ų117140.3 Ų140.355%0.54766%0.659SS.*Hα-helixtrans-55.5-53170.4-103167.8-179.300112.9R377 R383 R384 D385R377-E381 PolarHBondContact O-N 3.11Å; E381-R383 PolarHBondContact O-N 2.96Å; E381-R384 PolarHBondContact O-N 2.82Å; E381-D385 PolarHBondContact O-N 2.8Å
382R49.6Very low48.3Very low221 Ų221140.8 Ų140.883%0.83467%0.669SS**THydrogen-bonded Turntrans-63.8-2.7176.8-79.9-176.8164-171.5-5.7115.3K378K378-R382 PolarHBondContact O-N 2.86Å
383R50.1Low46.4Very low197 Ų197142.5 Ų142.574%0.74369%0.691SS**THydrogen-bonded Turntrans-105.3-10.6171-83.4179.6144.5-173.1-10.1113.2R380 E381R380-R383 PolarHBondContact O-N 2.91Å; R380-R383 VanDerWaalsContact O-N 3.13Å; E381-R383 PolarHBondContact O-N 2.96Å
384R46.4Very low45.1Very low188 Ų188149 Ų14971%0.70972%0.716SS**THydrogen-bonded Turntrans-96.3-17.3178.3-134.2177.2-178-177.3-3.2112.7R380 E381 G386 G387R380-R384 PolarHBondContact O-N 3.19Å; E381-R384 PolarHBondContact O-N 2.82Å; R384-G386 PolarHBondContact O-N 2.78Å; R384-G387 PolarHBondContact O-N 3.27Å
385D43.3Very low43.9Very low159 Ų159152.8 Ų152.885%0.8573%0.731SS**THydrogen-bonded Turntrans-69.948.1174-161.527.3000113.1E381E381-D385 PolarHBondContact O-N 2.8Å
386G42.7Very low42.6Very low80 Ų80154 Ų15483%0.82574%0.744SS**THydrogen-bonded Turntrans-166.712.3-173.500000114.6R384R384-G386 PolarHBondContact O-N 2.78Å
387G40.7Very low41.8Very low56 Ų56161.2 Ų161.258%0.57778%0.779SS**SBendtrans179.8102175.900000113.4R384R384-G387 PolarHBondContact O-N 3.27Å
388E38.7Very low40.8Very low195 Ų195159.3 Ų159.391%0.91178%0.78SS**  trans45.9143.9156.8-67.8175.1174.200121.6
389E40.5Very low40.6Very low195 Ų195158.7 Ų158.791%0.91178%0.784SS**  trans-83.2132.2-177.1-59172152.900110.7
390E34.3Very low40.2Very low185 Ų185152 Ų15286%0.86477%0.772SS**  trans-137146158.8-80.5-166.9151.600109.4
391E37.4Very low39.8Very low192 Ų192149.7 Ų149.790%0.89777%0.773SS**  trans-71.1148.3-158.5-63.4176.4124.300115
392D34.1Very low40Very low172 Ų172149.9 Ų149.992%0.9278%0.778SS**  trans-63.9135.2171.6-76.6-48.6000111.4
393T29.9Very low40.2Very low137 Ų137143.6 Ų143.684%0.8476%0.757SS**  trans-123139.7160.2-24.40000108.7
394E35.8Very low40.5Very low193 Ų193137.9 Ų137.990%0.90274%0.741SS**PPolyproline II helixtrans-61.7139.8-158.6-64174.3125.500115G396E394-G396 PolarHBondContact O-N 2.86Å
395E32.7Very low41.2Very low160 Ų160132.6 Ų132.675%0.74873%0.727SS**PPolyproline II helixtrans-68118.5-177.2-67.1-179153.300111.4R377R377-E395 IonicContact CZ-OE1 2.72Å; R377-E395 IonicContact NH1-OE1 3.59Å; R377-E395 PolarHBondContact NH1-OE1 2.84Å; R377-E395 IonicContact NH2-OE1 3.35Å; R377-E395 PolarHBondContact NH2-OE1 2.95Å
396G29.9Very low42.3Very low71 Ų71129.1 Ų129.173%0.73270%0.702SS**PPolyproline II helixtrans-93.2134.2166.200000111.5E394 D398E394-G396 PolarHBondContact O-N 2.86Å; G396-D398 PolarHBondContact O-N 2.98Å; G396-D398 VanDerWaalsContact O-N 3.07Å
397E38.6Very low43.5Very low206 Ų206126.2 Ų126.296%0.96367%0.667SS**SBendtrans-73.492.7-174.7-60.8-178.2143.100113.5
398D34.5Very low44.8Very low122 Ų122130.1 Ų130.165%0.65266%0.664SS**  trans-144.467.3156.6-158.8-1.7000112.5G396 G400G396-D398 PolarHBondContact O-N 2.98Å; G396-D398 VanDerWaalsContact O-N 3.07Å; D398-G400 PolarHBondContact O-N 2.86Å
399D45.2Very low46.3Very low124 Ų124125.4 Ų125.466%0.66364%0.642SS**THydrogen-bonded Turntrans-78.824.2-171-164.935.2000113.2K403D399-K403 PolarHBondContact O-NZ 2.8Å; D399-K403 IonicContact OD1-NZ 3.48Å; D399-K403 PolarHBondContact OD1-NZ 3.32Å; D399-K403 IonicContact OD2-NZ 3.55Å; D399-K403 PolarHBondContact OD2-NZ 3.25Å
400G42.1Very low47.8Very low45 Ų45118.1 Ų118.146%0.46461%0.608SS.*THydrogen-bonded Turntrans-94.7-64.6-175.300000114.2D398D398-G400 PolarHBondContact O-N 2.86Å
401D41Very low49.6Very low128 Ų128113.1 Ų113.168%0.68458%0.584SS**THydrogen-bonded Turntrans-75.2-33.1-168.5-78-20.1000113.2K403 D404D401-K403 PolarHBondContact O-N 2.97Å; D401-D404 PolarHBondContact O-N 2.85Å
402D52.5Low51.4Low122 Ų122109.7 Ų109.765%0.65257%0.568SS**Hα-helixtrans-53.4-26.6179.5-1093.9000114.4Y406D402-Y406 WeakPolarHBondContact O-CB 3.29Å; D402-Y406 PolarHBondContact O-N 3.48Å; D402-Y406 VanDerWaalsContact O-N 3.16Å
403K54.9Low53.5Low89 Ų89106.2 Ų106.239%0.38755%0.545SS..Hα-helixtrans-78.3-34.7-175.2-68.4-174.6178.3710113.1D399 D401 W407D399-K403 PolarHBondContact O-NZ 2.8Å; D399-K403 IonicContact OD1-NZ 3.48Å; D399-K403 PolarHBondContact OD1-NZ 3.32Å; D399-K403 IonicContact OD2-NZ 3.55Å; D399-K403 PolarHBondContact OD2-NZ 3.25Å; D401-K403 PolarHBondContact O-N 2.97Å; K403-W407 PolarHBondContact O-N 3.27Å
404D56Low55.6Low77 Ų77100.8 Ų100.841%0.41251%0.511SS..Hα-helixtrans-79.3-32.1177.9-96.1-33.4000111.8D401 W407 R408 K450D401-D404 PolarHBondContact O-N 2.85Å; D404-W407 PolarHBondContact O-N 3.26Å; D404-R408 PolarHBondContact O-N 2.89Å; D404-K450 IonicContact OD1-NZ 2.72Å; D404-K450 PolarHBondContact OD1-NZ 2.69Å
405D60.3Low57.6Low77 Ų7796.3 Ų96.341%0.41249%0.49SS..Hα-helixtrans-68.4-39.5173-75.5-14.1000112.5W407 R408 E409D405-W407 VanDerWaalsContact C-N 3.28Å; D405-W407 PolarHBondContact O-N 2.98Å; D405-R408 PolarHBondContact O-N 3.05Å; D405-R408 IonicContact OD1-CZ 3.14Å; D405-R408 IonicContact OD1-NE 2.84Å; D405-R408 PolarHBondContact OD1-NE 3.27Å; D405-R408 IonicContact OD1-NH2 2.65Å; D405-R408 PolarHBondContact OD1-NH2 2.86Å; D405-E409 PolarHBondContact O-N 2.94Å
406Y66.4Low59.9Low85 Ų8593.9 Ų93.933%0.33348%0.481SS..Hα-helixtrans-57.3-39.7169.8176.4-92.4000112.9D402 Q410D402-Y406 WeakPolarHBondContact O-CB 3.29Å; D402-Y406 PolarHBondContact O-N 3.48Å; D402-Y406 VanDerWaalsContact O-N 3.16Å; Y406-Q410 HydrophobicContact CD1-CG 4.47Å; Y406-Q410 HydrophobicContact CE1-CG 3.97Å; Y406-Q410 HydrophobicContact CE2-CG 4.15Å; Y406-Q410 WeakPolarHBondContact O-CG 3.47Å; Y406-Q410 PolarHBondContact O-N 3.16Å
407W68.2Low62.1Low20 Ų2094.7 Ų94.78%0.07647%0.466CS..Hα-helixtrans-69.4-41.5176.7-71.4125.7000111.9K403 D404 D405 Q410 Q411 L446 E449 K450K403-W407 PolarHBondContact O-N 3.27Å; D404-W407 PolarHBondContact O-N 3.26Å; D405-W407 VanDerWaalsContact C-N 3.28Å; D405-W407 PolarHBondContact O-N 2.98Å; W407-Q410 PolarHBondContact O-N 2.8Å; W407-Q411 WeakPolarHBondContact O-CG 3.44Å; W407-Q411 PolarHBondContact O-N 2.99Å; W407-Q411 VanDerWaalsContact O-N 3.08Å; W407-L446 HydrophobicContact CE3-CD1 4.2Å; W407-L446 HydrophobicContact CE3-CD2 4.46Å; W407-L446 HydrophobicContact CE3-CG 4.12Å; W407-L446 HydrophobicContact CZ3-CD1 3.65Å; W407-L446 HydrophobicContact CZ3-CG 3.8Å; W407-E449 HydrophobicContact CH2-CB 4.14Å; W407-E449 HydrophobicContact CH2-CG 4.11Å; W407-K450 HydrophobicContact CB-CD 4.36Å; W407-K450 HydrophobicContact CD2-CD 4.42Å; W407-K450 HydrophobicContact CG-CD 4.11Å; W407-K450 HydrophobicContact CH2-CB 4.37Å; W407-K450 HydrophobicContact CZ2-CB 4.13Å
408R67.9Low64Low137 Ų13787.5 Ų87.552%0.51743%0.431SS..Hα-helixtrans-58.3-52.2174.3-77.8-172.8-90.4-119.90.2111.2D404 D405 Q410 Q411 E412D404-R408 PolarHBondContact O-N 2.89Å; D405-R408 PolarHBondContact O-N 3.05Å; D405-R408 IonicContact OD1-CZ 3.14Å; D405-R408 IonicContact OD1-NE 2.84Å; D405-R408 PolarHBondContact OD1-NE 3.27Å; D405-R408 IonicContact OD1-NH2 2.65Å; D405-R408 PolarHBondContact OD1-NH2 2.86Å; R408-Q410 VanDerWaalsContact C-N 3.3Å; R408-Q410 PolarHBondContact O-N 3.42Å; R408-Q411 PolarHBondContact O-N 3.36Å; R408-Q411 VanDerWaalsContact O-N 3.1Å; R408-E412 PolarHBondContact O-N 3.39Å
409E71.1Confident66Low96 Ų9687.3 Ų87.345%0.44943%0.425SS..Hα-helixtrans-56-41.5178.1-80.5-158.5-179.600113.2D405 K413D405-E409 PolarHBondContact O-N 2.94Å; E409-K413 VanDerWaalsContact O-CB 3.29Å; E409-K413 WeakPolarHBondContact O-CB 3.29Å; E409-K413 VanDerWaalsContact O-CG 3.27Å; E409-K413 WeakPolarHBondContact O-CG 3.27Å; E409-K413 PolarHBondContact O-N 3.43Å; E409-K413 IonicContact OE2-NZ 2.71Å; E409-K413 PolarHBondContact OE2-NZ 2.77Å
410Q70.9Confident67.7Low42 Ų4284 Ų8420%0.19642%0.415CS..Hα-helixtrans-71.4-32.6-179.8-70.1-58.6-5900112.2Y406 W407 R408 L414 L446Y406-Q410 HydrophobicContact CD1-CG 4.47Å; Y406-Q410 HydrophobicContact CE1-CG 3.97Å; Y406-Q410 HydrophobicContact CE2-CG 4.15Å; Y406-Q410 WeakPolarHBondContact O-CG 3.47Å; Y406-Q410 PolarHBondContact O-N 3.16Å; W407-Q410 PolarHBondContact O-N 2.8Å; R408-Q410 VanDerWaalsContact C-N 3.3Å; R408-Q410 PolarHBondContact O-N 3.42Å; Q410-L414 WeakPolarHBondContact O-CB 3.5Å; Q410-L414 WeakPolarHBondContact O-CD1 3.48Å; Q410-L414 VanDerWaalsContact O-CG 3.29Å; Q410-L414 WeakPolarHBondContact O-CG 3.39Å; Q410-L414 PolarHBondContact O-N 3.14Å; Q410-L446 HydrophobicContact CB-CD2 4.15Å
411Q71.3Confident69.2Low80 Ų8083 Ų8337%0.37440%0.399SS..Hα-helixtrans-68-48.8171.9-71.2-177.1-69.500110.7W407 R408 K413 L414 E415 L446W407-Q411 WeakPolarHBondContact O-CG 3.44Å; W407-Q411 PolarHBondContact O-N 2.99Å; W407-Q411 VanDerWaalsContact O-N 3.08Å; R408-Q411 PolarHBondContact O-N 3.36Å; R408-Q411 VanDerWaalsContact O-N 3.1Å; Q411-K413 PolarHBondContact O-N 2.97Å; Q411-L414 PolarHBondContact O-N 3.12Å; Q411-E415 PolarHBondContact O-N 3.35Å; Q411-L446 HydrophobicContact CG-CD2 4.08Å
412E76.9Confident70.8Confident120 Ų12080.6 Ų80.656%0.56139%0.388SS*.Hα-helixtrans-60.7-44178.4-71.2-178172.800112.4R408 L414 E415 I416R408-E412 PolarHBondContact O-N 3.39Å; E412-L414 VanDerWaalsContact C-N 3.35Å; E412-L414 PolarHBondContact O-N 3.33Å; E412-E415 PolarHBondContact O-N 2.71Å; E412-I416 WeakPolarHBondContact O-CB 3.43Å; E412-I416 VanDerWaalsContact O-CG1 3.26Å; E412-I416 WeakPolarHBondContact O-CG1 3.25Å; E412-I416 PolarHBondContact O-N 3.16Å
413K78.1Confident71.9Confident100 Ų10081.4 Ų81.444%0.43539%0.388SS..Hα-helixtrans-59.5-43.2175-77.3165.6-179.1160.20111.7E409 Q411 I416 E417E409-K413 VanDerWaalsContact O-CB 3.29Å; E409-K413 WeakPolarHBondContact O-CB 3.29Å; E409-K413 VanDerWaalsContact O-CG 3.27Å; E409-K413 WeakPolarHBondContact O-CG 3.27Å; E409-K413 PolarHBondContact O-N 3.43Å; E409-K413 IonicContact OE2-NZ 2.71Å; E409-K413 PolarHBondContact OE2-NZ 2.77Å; Q411-K413 PolarHBondContact O-N 2.97Å; K413-I416 PolarHBondContact O-N 2.57Å; K413-E417 WeakPolarHBondContact O-CB 3.33Å; K413-E417 VanDerWaalsContact O-CG 3.3Å; K413-E417 WeakPolarHBondContact O-CG 3.49Å; K413-E417 PolarHBondContact O-N 2.92Å
414L73.8Confident72.8Confident22 Ų2280.3 Ų80.312%0.11539%0.386CS..Hα-helixtrans-68.3-32.9176.6-74.1170.2000112.9Q410 Q411 E412 K418 K439 M443 L446Q410-L414 WeakPolarHBondContact O-CB 3.5Å; Q410-L414 WeakPolarHBondContact O-CD1 3.48Å; Q410-L414 VanDerWaalsContact O-CG 3.29Å; Q410-L414 WeakPolarHBondContact O-CG 3.39Å; Q410-L414 PolarHBondContact O-N 3.14Å; Q411-L414 PolarHBondContact O-N 3.12Å; E412-L414 VanDerWaalsContact C-N 3.35Å; E412-L414 PolarHBondContact O-N 3.33Å; L414-K418 VanDerWaalsContact O-CB 3.31Å; L414-K418 WeakPolarHBondContact O-CB 3.33Å; L414-K418 PolarHBondContact O-N 3.4Å; L414-K439 HydrophobicContact CD2-CD 4.06Å; L414-M443 HydrophobicContact CB-CG 3.95Å; L414-M443 HydrophobicContact CB-SD 4.33Å; L414-M443 HydrophobicContact CD1-CG 3.89Å; L414-L446 HydrophobicContact CD1-CD2 4.2Å
415E77.9Confident73.3Confident99 Ų9985.2 Ų85.246%0.46341%0.406SS..Hα-helixtrans-71.9-41.3174.1-75.4-163.8178.800113.1Q411 E412 K418 K419 M443Q411-E415 PolarHBondContact O-N 3.35Å; E412-E415 PolarHBondContact O-N 2.71Å; E415-K418 PolarHBondContact O-N 2.99Å; E415-K419 WeakPolarHBondContact O-CG 3.38Å; E415-K419 PolarHBondContact O-N 3.02Å; E415-M443 HydrophobicContact CG-SD 4.32Å
416I80.6Confident73.5Confident110 Ų11086.7 Ų86.756%0.56442%0.423SS*.Hα-helixtrans-62.2-46.6175-68.7163.7000109.7E412 K413 K418 K419 A420E412-I416 WeakPolarHBondContact O-CB 3.43Å; E412-I416 VanDerWaalsContact O-CG1 3.26Å; E412-I416 WeakPolarHBondContact O-CG1 3.25Å; E412-I416 PolarHBondContact O-N 3.16Å; K413-I416 PolarHBondContact O-N 2.57Å; I416-K418 VanDerWaalsContact C-N 3.33Å; I416-K418 PolarHBondContact O-N 3.33Å; I416-K419 PolarHBondContact O-N 2.88Å; I416-A420 PolarHBondContact O-N 2.85Å
417E76.9Confident73.4Confident87 Ų8785.2 Ų85.241%0.40742%0.421SS..Hα-helixtrans-61.8-38.4173.8-72.2179.213300112.2K413 A420 I421 K439K413-E417 WeakPolarHBondContact O-CB 3.33Å; K413-E417 VanDerWaalsContact O-CG 3.3Å; K413-E417 WeakPolarHBondContact O-CG 3.49Å; K413-E417 PolarHBondContact O-N 2.92Å; E417-A420 PolarHBondContact O-N 2.73Å; E417-I421 WeakPolarHBondContact O-CD1 3.44Å; E417-I421 VanDerWaalsContact O-CG1 3.27Å; E417-I421 WeakPolarHBondContact O-CG1 3.28Å; E417-I421 PolarHBondContact O-N 2.81Å; E417-I421 VanDerWaalsContact O-N 3.1Å; E417-K439 IonicContact OE1-NZ 2.63Å; E417-K439 PolarHBondContact OE1-NZ 3.33Å; E417-K439 IonicContact OE2-NZ 2.72Å; E417-K439 PolarHBondContact OE2-NZ 2.71Å
418K77.6Confident73.5Confident56 Ų5689 Ų8924%0.24345%0.445CS..Hα-helixtrans-63-42.7175.3-169.6178.7-173178.70111.2L414 E415 I416 V422 L436 E440 M443L414-K418 VanDerWaalsContact O-CB 3.31Å; L414-K418 WeakPolarHBondContact O-CB 3.33Å; L414-K418 PolarHBondContact O-N 3.4Å; E415-K418 PolarHBondContact O-N 2.99Å; I416-K418 VanDerWaalsContact C-N 3.33Å; I416-K418 PolarHBondContact O-N 3.33Å; K418-V422 WeakPolarHBondContact O-CG2 3.49Å; K418-V422 PolarHBondContact O-N 2.84Å; K418-L436 HydrophobicContact CG-CD2 3.72Å; K418-E440 IonicContact NZ-OE1 3.18Å; K418-E440 PolarHBondContact NZ-OE1 2.94Å; K418-M443 HydrophobicContact CD-CE 3.76Å
419K77.3Confident73.6Confident117 Ų11786 Ų8651%0.50945%0.451SS..Hα-helixtrans-64.2-47.4176.2-73167.5-177.7163.40111.6E415 I416 I421 V422 E423E415-K419 WeakPolarHBondContact O-CG 3.38Å; E415-K419 PolarHBondContact O-N 3.02Å; I416-K419 PolarHBondContact O-N 2.88Å; K419-I421 VanDerWaalsContact C-N 3.31Å; K419-I421 PolarHBondContact O-N 2.93Å; K419-V422 CarbonylContact O-C 3.59Å; K419-V422 WeakPolarHBondContact O-CA 3.49Å; K419-V422 WeakPolarHBondContact O-CB 3.44Å; K419-V422 PolarHBondContact O-N 2.77Å; K419-E423 PolarHBondContact O-N 3.2Å
420A79.4Confident73.5Confident55 Ų5589.3 Ų89.346%0.45547%0.466SS..Hα-helixtrans-57-41.6177.300000112.7I416 E417 V422 E423 D424I416-A420 PolarHBondContact O-N 2.85Å; E417-A420 PolarHBondContact O-N 2.73Å; A420-V422 VanDerWaalsContact C-N 3.31Å; A420-V422 PolarHBondContact O-N 3.2Å; A420-E423 PolarHBondContact O-N 2.79Å; A420-D424 PolarHBondContact O-N 2.65Å
421I74.3Confident73.6Confident25 Ų2591.5 Ų91.513%0.12848%0.476CS..Hα-helixtrans-66.3-31.4175.4-65.8160.6000111.9E417 K419 K432 L435 L436 K439E417-I421 WeakPolarHBondContact O-CD1 3.44Å; E417-I421 VanDerWaalsContact O-CG1 3.27Å; E417-I421 WeakPolarHBondContact O-CG1 3.28Å; E417-I421 PolarHBondContact O-N 2.81Å; E417-I421 VanDerWaalsContact O-N 3.1Å; K419-I421 VanDerWaalsContact C-N 3.31Å; K419-I421 PolarHBondContact O-N 2.93Å; I421-K432 HydrophobicContact CG2-CG 4.21Å; I421-K432 WeakPolarHBondContact O-CE 3.32Å; I421-K432 PolarHBondContact O-NZ 2.83Å; I421-L435 HydrophobicContact CD1-CB 4.28Å; I421-L435 HydrophobicContact CG2-CB 4.21Å; I421-L436 HydrophobicContact CG2-CD2 4.25Å; I421-L436 HydrophobicContact CG2-CG 4.04Å; I421-K439 HydrophobicContact CD1-CG 4.11Å
422V74.7Confident73.8Confident77 Ų7789.5 Ų89.547%0.46747%0.466SS..Hα-helixtrans-73.7-35.8175173.10000112K418 K419 A420 K432 L436K418-V422 WeakPolarHBondContact O-CG2 3.49Å; K418-V422 PolarHBondContact O-N 2.84Å; K419-V422 CarbonylContact O-C 3.59Å; K419-V422 WeakPolarHBondContact O-CA 3.49Å; K419-V422 WeakPolarHBondContact O-CB 3.44Å; K419-V422 PolarHBondContact O-N 2.77Å; A420-V422 VanDerWaalsContact C-N 3.31Å; A420-V422 PolarHBondContact O-N 3.2Å; V422-K432 WeakPolarHBondContact O-CE 3.38Å; V422-K432 PolarHBondContact O-NZ 3.33Å; V422-L436 HydrophobicContact CG2-CD1 4.29Å; V422-L436 HydrophobicContact CG2-CD2 3.85Å
423E74.8Confident73.6Confident138 Ų13890.3 Ų90.365%0.64547%0.472SS*.Hα-helixtrans-83.9-21.9-177.6-70.3170-176.400113.3K419 A420 H425K419-E423 PolarHBondContact O-N 3.2Å; A420-E423 PolarHBondContact O-N 2.79Å; E423-H425 PolarHBondContact O-CD2 3.08Å; E423-H425 PolarHBondContact O-N 3.24Å
424D73.9Confident73.8Confident66 Ų6693.2 Ų93.235%0.35348%0.48SS..  trans-67.8114.5175.4-171.8-1.9000111.9A420 S426 L427 K432A420-D424 PolarHBondContact O-N 2.65Å; D424-S426 WeakPolarHBondContact OD1-CB 3.32Å; D424-S426 PolarHBondContact OD1-N 3.16Å; D424-L427 HydrophobicContact CB-CD1 4.12Å; D424-L427 WeakPolarHBondContact OD2-CD1 3.47Å; D424-L427 WeakPolarHBondContact OD2-CG 3.31Å; D424-K432 PolarHBondContact O-NZ 2.78Å
425H67.1Low74Confident180 Ų18094.5 Ų94.583%0.83349%0.486SS*.SBendtrans-89.7-5.2177.8-71.1-75000113.8E423E423-H425 PolarHBondContact O-CD2 3.08Å; E423-H425 PolarHBondContact O-N 3.24Å
426S65.5Low74Confident109 Ų10991.6 Ų91.676%0.76247%0.474SS*.SBendtrans-81.8-15.7179.8-170.70000113.9D424D424-S426 WeakPolarHBondContact OD1-CB 3.32Å; D424-S426 PolarHBondContact OD1-N 3.16Å
427L62.5Low74.1Confident54 Ų5494 Ų9428%0.28348%0.48SS..SBendtrans-88.7140.1-172.3-69.6169.1000113.2D424 K432D424-L427 HydrophobicContact CB-CD1 4.12Å; D424-L427 WeakPolarHBondContact OD2-CD1 3.47Å; D424-L427 WeakPolarHBondContact OD2-CG 3.31Å; L427-K432 HydrophobicContact CB-CB 4.35Å
428V70.3Confident74.3Confident98 Ų9894 Ų9459%0.59448%0.48SS*.  trans-63.3136172.2-179.30000109.8E430 E431 K432V428-E430 VanDerWaalsContact C-N 3.28Å; V428-E430 PolarHBondContact O-N 3.08Å; V428-E430 VanDerWaalsContact O-N 3.16Å; V428-E431 PolarHBondContact O-N 2.89Å; V428-K432 PolarHBondContact O-N 2.87Å
429A69.9Low74.3Confident76 Ų7693 Ų9363%0.62848%0.476SS*.Hα-helixtrans-55.7-36.5-171.500000114.3M433A429-M433 WeakPolarHBondContact O-CB 3.31Å; A429-M433 PolarHBondContact O-N 3.36Å
430E70.4Confident74.4Confident165 Ų16592.5 Ų92.577%0.77148%0.475SS*.Hα-helixtrans-66.6-41.3176.1-65.9-169.1140.300112.7V428 M433 R434V428-E430 VanDerWaalsContact C-N 3.28Å; V428-E430 PolarHBondContact O-N 3.08Å; V428-E430 VanDerWaalsContact O-N 3.16Å; E430-M433 PolarHBondContact O-N 3.12Å; E430-R434 PolarHBondContact O-N 3.21Å
431E73.3Confident74.5Confident87 Ų8796.5 Ų96.541%0.40748%0.483SS..Hα-helixtrans-71.2-41.3-179-173.4159.2-138.300111.2V428 M433 R434 L435V428-E431 PolarHBondContact O-N 2.89Å; E431-M433 VanDerWaalsContact C-N 3.34Å; E431-M433 PolarHBondContact O-N 3.35Å; E431-R434 WeakPolarHBondContact O-CB 3.39Å; E431-R434 PolarHBondContact O-N 3.24Å; E431-R434 VanDerWaalsContact O-N 3.16Å; E431-R434 IonicContact OE1-NH2 3.79Å; E431-L435 HydrophobicContact CG-CD1 4.39Å; E431-L435 WeakPolarHBondContact O-CG 3.49Å; E431-L435 PolarHBondContact O-N 3.27Å
432K73.8Confident74.6Confident38 Ų3899.8 Ų99.817%0.16550%0.496CS..Hα-helixtrans-56.4-45.4170.2-175.5164.8179.2148.40111.9I421 V422 D424 L427 V428 L435 L436I421-K432 HydrophobicContact CG2-CG 4.21Å; I421-K432 WeakPolarHBondContact O-CE 3.32Å; I421-K432 PolarHBondContact O-NZ 2.83Å; V422-K432 WeakPolarHBondContact O-CE 3.38Å; V422-K432 PolarHBondContact O-NZ 3.33Å; D424-K432 PolarHBondContact O-NZ 2.78Å; L427-K432 HydrophobicContact CB-CB 4.35Å; V428-K432 PolarHBondContact O-N 2.87Å; K432-L435 PolarHBondContact O-N 3.32Å; K432-L436 HydrophobicContact CG-CD1 4.36Å; K432-L436 WeakPolarHBondContact O-CB 3.48Å; K432-L436 WeakPolarHBondContact O-CG 3.41Å; K432-L436 PolarHBondContact O-N 3.41Å
433M74Confident74.7Confident138 Ų13898 Ų9868%0.6848%0.483SS*.Hα-helixtrans-65.4-37.7175.8-166.9-174.4-66.700112.3A429 E430 E431 K437A429-M433 WeakPolarHBondContact O-CB 3.31Å; A429-M433 PolarHBondContact O-N 3.36Å; E430-M433 PolarHBondContact O-N 3.12Å; E431-M433 VanDerWaalsContact C-N 3.34Å; E431-M433 PolarHBondContact O-N 3.35Å; M433-K437 WeakPolarHBondContact O-CB 3.3Å; M433-K437 PolarHBondContact O-N 3.46Å; M433-K437 VanDerWaalsContact O-N 3.16Å
434R81.6Confident75Confident161 Ų16194.5 Ų94.561%0.60847%0.467SS*.Hα-helixtrans-64-47.1176.3-164-177.677.5-169.1-3.5111.8E430 E431 K437 E438E430-R434 PolarHBondContact O-N 3.21Å; E431-R434 WeakPolarHBondContact O-CB 3.39Å; E431-R434 PolarHBondContact O-N 3.24Å; E431-R434 VanDerWaalsContact O-N 3.16Å; E431-R434 IonicContact OE1-NH2 3.79Å; R434-K437 PolarHBondContact O-N 3.42Å; R434-E438 PolarHBondContact O-N 3.2Å; R434-E438 VanDerWaalsContact O-N 3.09Å
435L78.1Confident75.2Confident48 Ų4895 Ų9525%0.25147%0.469SS..Hα-helixtrans-64.7-42.8179.7-70.7171000112.1I421 E431 K432 K437 E438 K439I421-L435 HydrophobicContact CD1-CB 4.28Å; I421-L435 HydrophobicContact CG2-CB 4.21Å; E431-L435 HydrophobicContact CG-CD1 4.39Å; E431-L435 WeakPolarHBondContact O-CG 3.49Å; E431-L435 PolarHBondContact O-N 3.27Å; K432-L435 PolarHBondContact O-N 3.32Å; L435-K437 PolarHBondContact O-N 3.27Å; L435-E438 PolarHBondContact O-N 3.08Å; L435-K439 WeakPolarHBondContact O-CG 3.47Å; L435-K439 PolarHBondContact O-N 3.43Å
436L78.6Confident75.6Confident39 Ų3988 Ų8820%0.20444%0.438CS..Hα-helixtrans-58.2-47.3175.2-77.5168.7000111.9K418 I421 V422 K432 E438 K439 E440K418-L436 HydrophobicContact CG-CD2 3.72Å; I421-L436 HydrophobicContact CG2-CD2 4.25Å; I421-L436 HydrophobicContact CG2-CG 4.04Å; V422-L436 HydrophobicContact CG2-CD1 4.29Å; V422-L436 HydrophobicContact CG2-CD2 3.85Å; K432-L436 HydrophobicContact CG-CD1 4.36Å; K432-L436 WeakPolarHBondContact O-CB 3.48Å; K432-L436 WeakPolarHBondContact O-CG 3.41Å; K432-L436 PolarHBondContact O-N 3.41Å; L436-E438 VanDerWaalsContact C-N 3.29Å; L436-E438 PolarHBondContact O-N 3.31Å; L436-K439 PolarHBondContact O-N 2.85Å; L436-E440 VanDerWaalsContact O-CB 3.3Å; L436-E440 WeakPolarHBondContact O-CB 3.45Å; L436-E440 PolarHBondContact O-N 2.77Å
437K82.1Confident76.3Confident159 Ų15988.7 Ų88.769%0.69142%0.424SS*.Hα-helixtrans-63.1-34.2178.3-170.4172.4-176.5173.50112.7M433 R434 L435 K441M433-K437 WeakPolarHBondContact O-CB 3.3Å; M433-K437 PolarHBondContact O-N 3.46Å; M433-K437 VanDerWaalsContact O-N 3.16Å; R434-K437 PolarHBondContact O-N 3.42Å; L435-K437 PolarHBondContact O-N 3.27Å; K437-K441 WeakPolarHBondContact O-CB 3.18Å; K437-K441 PolarHBondContact O-N 3.45Å; K437-K441 VanDerWaalsContact O-N 3.07Å
438E81.6Confident77.2Confident88 Ų8892.3 Ų92.341%0.41143%0.434SS..Hα-helixtrans-71-42.8176-162.2-165.8136.700112.5R434 L435 L436 K441 K442R434-E438 PolarHBondContact O-N 3.2Å; R434-E438 VanDerWaalsContact O-N 3.09Å; L435-E438 PolarHBondContact O-N 3.08Å; L436-E438 VanDerWaalsContact C-N 3.29Å; L436-E438 PolarHBondContact O-N 3.31Å; E438-K441 PolarHBondContact O-N 2.88Å; E438-K442 WeakPolarHBondContact O-CG 3.35Å; E438-K442 PolarHBondContact O-N 2.96Å; E438-K442 WeakPolarHBondContact OE1-CE 3.37Å; E438-K442 IonicContact OE1-NZ 2.65Å; E438-K442 PolarHBondContact OE1-NZ 2.65Å
439K77.9Confident77.6Confident35 Ų3590.9 Ų90.915%0.15242%0.421CS..Hα-helixtrans-67-38.9176.4-67.2-73-174.9172.60111.9L414 E417 I421 L435 L436 K442 M443L414-K439 HydrophobicContact CD2-CD 4.06Å; E417-K439 IonicContact OE1-NZ 2.63Å; E417-K439 PolarHBondContact OE1-NZ 3.33Å; E417-K439 IonicContact OE2-NZ 2.72Å; E417-K439 PolarHBondContact OE2-NZ 2.71Å; I421-K439 HydrophobicContact CD1-CG 4.11Å; L435-K439 WeakPolarHBondContact O-CG 3.47Å; L435-K439 PolarHBondContact O-N 3.43Å; L436-K439 PolarHBondContact O-N 2.85Å; K439-K442 WeakPolarHBondContact O-CB 2.88Å; K439-K442 PolarHBondContact O-N 3.34Å; K439-M443 PolarHBondContact O-N 3.04Å
440E78.6Confident78Confident106 Ų10689.3 Ų89.350%0.49540%0.399SS..Hα-helixtrans-65.9-42.1176.1-167.4155.5-98.200112K418 L436 K442 M443 E444K418-E440 IonicContact NZ-OE1 3.18Å; K418-E440 PolarHBondContact NZ-OE1 2.94Å; L436-E440 VanDerWaalsContact O-CB 3.3Å; L436-E440 WeakPolarHBondContact O-CB 3.45Å; L436-E440 PolarHBondContact O-N 2.77Å; E440-K442 VanDerWaalsContact C-N 3.34Å; E440-K442 PolarHBondContact O-N 3.39Å; E440-M443 PolarHBondContact O-N 3.5Å; E440-E444 PolarHBondContact O-N 3.22Å
441K81.7Confident78.5Confident139 Ų13984.9 Ų84.960%0.60438%0.379SS*.Hα-helixtrans-59.7-43.5170-174.8-178.8175.6-173.70111.9K437 E438 M443 E444 D445K437-K441 WeakPolarHBondContact O-CB 3.18Å; K437-K441 PolarHBondContact O-N 3.45Å; K437-K441 VanDerWaalsContact O-N 3.07Å; E438-K441 PolarHBondContact O-N 2.88Å; K441-M443 PolarHBondContact O-N 3.05Å; K441-E444 PolarHBondContact O-N 3.34Å; K441-D445 WeakPolarHBondContact O-CB 3.2Å; K441-D445 PolarHBondContact O-N 2.77Å
442K76.6Confident78.8Confident94 Ų9482.2 Ų82.241%0.40937%0.372SS..Hα-helixtrans-61.5-38.7176.9-79.5167.5171.5168.80112.8E438 K439 E440 L446E438-K442 WeakPolarHBondContact O-CG 3.35Å; E438-K442 PolarHBondContact O-N 2.96Å; E438-K442 WeakPolarHBondContact OE1-CE 3.37Å; E438-K442 IonicContact OE1-NZ 2.65Å; E438-K442 PolarHBondContact OE1-NZ 2.65Å; K439-K442 WeakPolarHBondContact O-CB 2.88Å; K439-K442 PolarHBondContact O-N 3.34Å; E440-K442 VanDerWaalsContact C-N 3.34Å; E440-K442 PolarHBondContact O-N 3.39Å; K442-L446 WeakPolarHBondContact O-CB 3.07Å; K442-L446 PolarHBondContact O-N 3.42Å
443M76.3Confident79Confident40 Ų4081.5 Ų81.520%0.19737%0.37CS..Hα-helixtrans-66.4-43.3173.8-80.5-168.7-72.300112.7L414 E415 K418 K439 E440 K441 L446 R447L414-M443 HydrophobicContact CB-CG 3.95Å; L414-M443 HydrophobicContact CB-SD 4.33Å; L414-M443 HydrophobicContact CD1-CG 3.89Å; E415-M443 HydrophobicContact CG-SD 4.32Å; K418-M443 HydrophobicContact CD-CE 3.76Å; K439-M443 PolarHBondContact O-N 3.04Å; E440-M443 PolarHBondContact O-N 3.5Å; K441-M443 PolarHBondContact O-N 3.05Å; M443-L446 WeakPolarHBondContact O-CB 3.36Å; M443-L446 PolarHBondContact O-N 2.9Å; M443-R447 PolarHBondContact O-N 3.06Å
444E80.7Confident79.3Confident65 Ų6579.7 Ų79.730%0.30436%0.36SS..Hα-helixtrans-64.5-42.3177.5176.964.4-170.200111.9E440 K441 L446 R447 R448E440-E444 PolarHBondContact O-N 3.22Å; K441-E444 PolarHBondContact O-N 3.34Å; E444-L446 VanDerWaalsContact C-N 3.35Å; E444-L446 PolarHBondContact O-N 2.8Å; E444-R447 PolarHBondContact O-N 2.81Å; E444-R447 IonicContact OE2-NH1 3.49Å; E444-R448 WeakPolarHBondContact O-CG 3.15Å; E444-R448 PolarHBondContact O-N 2.95Å; E444-R448 IonicContact OE1-CZ 3.6Å; E444-R448 IonicContact OE1-NE 2.77Å; E444-R448 PolarHBondContact OE1-NE 2.87Å; E444-R448 IonicContact OE1-NH2 2.73Å; E444-R448 PolarHBondContact OE1-NH2 2.75Å
445D79Confident79.3Confident75 Ų7578.2 Ų78.240%0.40136%0.362SS..Hα-helixtrans-63.4-39.8175-70.7-26.1000111.3K441 R448 E449K441-D445 WeakPolarHBondContact O-CB 3.2Å; K441-D445 PolarHBondContact O-N 2.77Å; D445-R448 IonicContact OD1-NH1 3.72Å; D445-E449 PolarHBondContact O-N 3.33Å
446L76.3Confident79.3Confident33 Ų3376.9 Ų76.917%0.17336%0.355CS..Hα-helixtrans-63.2-42.5174.8-161.981000111.9W407 Q410 Q411 L414 K442 M443 E444 E449 K450W407-L446 HydrophobicContact CE3-CD1 4.2Å; W407-L446 HydrophobicContact CE3-CD2 4.46Å; W407-L446 HydrophobicContact CE3-CG 4.12Å; W407-L446 HydrophobicContact CZ3-CD1 3.65Å; W407-L446 HydrophobicContact CZ3-CG 3.8Å; Q410-L446 HydrophobicContact CB-CD2 4.15Å; Q411-L446 HydrophobicContact CG-CD2 4.08Å; L414-L446 HydrophobicContact CD1-CD2 4.2Å; K442-L446 WeakPolarHBondContact O-CB 3.07Å; K442-L446 PolarHBondContact O-N 3.42Å; M443-L446 WeakPolarHBondContact O-CB 3.36Å; M443-L446 PolarHBondContact O-N 2.9Å; E444-L446 VanDerWaalsContact C-N 3.35Å; E444-L446 PolarHBondContact O-N 2.8Å; L446-E449 PolarHBondContact O-N 3.05Å; L446-K450 PolarHBondContact O-N 2.86Å
447R79.2Confident79.3Confident124 Ų12477 Ų7747%0.46836%0.359SS..Hα-helixtrans-65.3-43.9179.8-150.5-171.188-152.80.3111.6M443 E444 E449 K450 E451M443-R447 PolarHBondContact O-N 3.06Å; E444-R447 PolarHBondContact O-N 2.81Å; E444-R447 IonicContact OE2-NH1 3.49Å; R447-E449 VanDerWaalsContact C-N 3.3Å; R447-E449 PolarHBondContact O-N 2.95Å; R447-K450 PolarHBondContact O-N 3.46Å; R447-E451 IonicContact CZ-OE1 3.55Å; R447-E451 VanDerWaalsContact CZ-OE1 3.25Å; R447-E451 IonicContact NE-OE1 3.33Å; R447-E451 PolarHBondContact NE-OE1 3.13Å; R447-E451 IonicContact NH2-OE1 3.28Å; R447-E451 PolarHBondContact NH2-OE1 3.1Å; R447-E451 WeakPolarHBondContact O-CG 3.41Å; R447-E451 PolarHBondContact O-N 3.08Å
448R81.8Confident79.3Confident131 Ų13172.2 Ų72.249%0.49435%0.349SS..Hα-helixtrans-62.3-35.7174.1-69.7171.6-172.7169.50.9112.5E444 D445 A452E444-R448 WeakPolarHBondContact O-CG 3.15Å; E444-R448 PolarHBondContact O-N 2.95Å; E444-R448 IonicContact OE1-CZ 3.6Å; E444-R448 IonicContact OE1-NE 2.77Å; E444-R448 PolarHBondContact OE1-NE 2.87Å; E444-R448 IonicContact OE1-NH2 2.73Å; E444-R448 PolarHBondContact OE1-NH2 2.75Å; D445-R448 IonicContact OD1-NH1 3.72Å; R448-A452 WeakPolarHBondContact O-CB 3.49Å; R448-A452 PolarHBondContact O-N 2.97Å
449E78.1Confident79.2Confident68 Ų6872.4 Ų72.432%0.31835%0.348SS..Hα-helixtrans-65.1-45.7174.4-163.1-173.1157.600111K376 W407 D445 L446 R447 A452 T453K376-E449 VanDerWaalsContact CE-OE1 3.28Å; K376-E449 WeakPolarHBondContact CE-OE1 3.39Å; K376-E449 IonicContact NZ-OE1 3.19Å; W407-E449 HydrophobicContact CH2-CB 4.14Å; W407-E449 HydrophobicContact CH2-CG 4.11Å; D445-E449 PolarHBondContact O-N 3.33Å; L446-E449 PolarHBondContact O-N 3.05Å; R447-E449 VanDerWaalsContact C-N 3.3Å; R447-E449 PolarHBondContact O-N 2.95Å; E449-A452 PolarHBondContact O-N 3.25Å; E449-T453 PolarHBondContact O-N 3.41Å; E449-T453 PolarHBondContact O-OG1 2.88Å
450K77.9Confident79.2Confident42 Ų4271.2 Ų71.218%0.18334%0.343CS..Hα-helixtrans-58.7-55.2175.3-178.3165.8-178.8156.10111.6D404 W407 L446 R447 A452 T453 E454D404-K450 IonicContact OD1-NZ 2.72Å; D404-K450 PolarHBondContact OD1-NZ 2.69Å; W407-K450 HydrophobicContact CB-CD 4.36Å; W407-K450 HydrophobicContact CD2-CD 4.42Å; W407-K450 HydrophobicContact CG-CD 4.11Å; W407-K450 HydrophobicContact CH2-CB 4.37Å; W407-K450 HydrophobicContact CZ2-CB 4.13Å; L446-K450 PolarHBondContact O-N 2.86Å; R447-K450 PolarHBondContact O-N 3.46Å; K450-A452 VanDerWaalsContact C-N 3.26Å; K450-A452 PolarHBondContact O-N 3.21Å; K450-T453 WeakPolarHBondContact CA-OG1 2.96Å; K450-T453 PolarHBondContact O-N 3.24Å; K450-T453 PolarHBondContact O-OG1 3.3Å; K450-E454 WeakPolarHBondContact CE-OE1 3.47Å; K450-E454 HydrophobicContact CG-CG 4.43Å; K450-E454 WeakPolarHBondContact CG-OE1 3.36Å; K450-E454 IonicContact NZ-OE1 3.47Å; K450-E454 PolarHBondContact O-N 2.91Å
451E81.6Confident79.2Confident73 Ų7372.9 Ų72.934%0.34135%0.349SS..Hα-helixtrans-52.9-42.1176.6-71.7170.9-166.400111.9R447 M455R447-E451 IonicContact CZ-OE1 3.55Å; R447-E451 VanDerWaalsContact CZ-OE1 3.25Å; R447-E451 IonicContact NE-OE1 3.33Å; R447-E451 PolarHBondContact NE-OE1 3.13Å; R447-E451 IonicContact NH2-OE1 3.28Å; R447-E451 PolarHBondContact NH2-OE1 3.1Å; R447-E451 WeakPolarHBondContact O-CG 3.41Å; R447-E451 PolarHBondContact O-N 3.08Å; E451-M455 WeakPolarHBondContact O-CB 3.5Å; E451-M455 PolarHBondContact O-N 3.02Å
452A79.9Confident79.1Confident31 Ų3168.6 Ų68.626%0.25634%0.34SS..Hα-helixtrans-70.4-34.6177.300000113.4R448 E449 K450 L456R448-A452 WeakPolarHBondContact O-CB 3.49Å; R448-A452 PolarHBondContact O-N 2.97Å; E449-A452 PolarHBondContact O-N 3.25Å; K450-A452 VanDerWaalsContact C-N 3.26Å; K450-A452 PolarHBondContact O-N 3.21Å; A452-L456 WeakPolarHBondContact O-CB 3.25Å; A452-L456 PolarHBondContact O-N 2.92Å; A452-L456 VanDerWaalsContact O-N 3.14Å
453T77.4Confident79.2Confident22 Ų2264.9 Ų64.914%0.13532%0.324CS..Hα-helixtrans-71.8-36.6173.448.80000112.7L369 E449 K450 L456 S457L369-T453 HydrophobicContact CD2-CG2 4.38Å; E449-T453 PolarHBondContact O-N 3.41Å; E449-T453 PolarHBondContact O-OG1 2.88Å; K450-T453 WeakPolarHBondContact CA-OG1 2.96Å; K450-T453 PolarHBondContact O-N 3.24Å; K450-T453 PolarHBondContact O-OG1 3.3Å; T453-L456 PolarHBondContact O-N 2.98Å; T453-S457 WeakPolarHBondContact O-CB 2.94Å; T453-S457 PolarHBondContact O-N 2.8Å
454E80.8Confident79.2Confident100 Ų10066.5 Ų66.547%0.46733%0.331SS..Hα-helixtrans-65.8-46.4174.5-73.3174.5-176.600111.4K450 L456 S457 A458K450-E454 WeakPolarHBondContact CE-OE1 3.47Å; K450-E454 HydrophobicContact CG-CG 4.43Å; K450-E454 WeakPolarHBondContact CG-OE1 3.36Å; K450-E454 IonicContact NZ-OE1 3.47Å; K450-E454 PolarHBondContact O-N 2.91Å; E454-L456 VanDerWaalsContact C-N 3.29Å; E454-L456 PolarHBondContact O-N 3.29Å; E454-S457 PolarHBondContact O-N 3.41Å; E454-A458 VanDerWaalsContact O-CB 3.27Å; E454-A458 WeakPolarHBondContact O-CB 3.46Å; E454-A458 PolarHBondContact O-N 3.11Å
455M82.3Confident79.2Confident130 Ų13066.1 Ų66.164%0.6434%0.336SS*.Hα-helixtrans-57.6-40.8172.9-86-171-85.900112.5E451 K459E451-M455 WeakPolarHBondContact O-CB 3.5Å; E451-M455 PolarHBondContact O-N 3.02Å; M455-K459 WeakPolarHBondContact O-CB 3.45Å; M455-K459 PolarHBondContact O-N 3.41Å
456L77.2Confident79.2Confident21 Ų2166.2 Ų66.211%0.1133%0.333CS..Hα-helixtrans-68.7-43.6179.2-174.558000111.7L365 Q368 L369 A452 T453 E454 K459 I460L365-L456 HydrophobicContact CB-CD1 3.82Å; L365-L456 HydrophobicContact CD1-CD1 4Å; L365-L456 HydrophobicContact CD2-CD1 3.63Å; L365-L456 HydrophobicContact CG-CD1 3.99Å; Q368-L456 HydrophobicContact CB-CD2 3.92Å; L369-L456 HydrophobicContact CD2-CB 4.14Å; L369-L456 HydrophobicContact CD2-CD2 3.7Å; L369-L456 HydrophobicContact CD2-CG 3.96Å; L369-L456 HydrophobicContact CG-CD2 3.7Å; L369-L456 HydrophobicContact CG-CG 3.87Å; A452-L456 WeakPolarHBondContact O-CB 3.25Å; A452-L456 PolarHBondContact O-N 2.92Å; A452-L456 VanDerWaalsContact O-N 3.14Å; T453-L456 PolarHBondContact O-N 2.98Å; E454-L456 VanDerWaalsContact C-N 3.29Å; E454-L456 PolarHBondContact O-N 3.29Å; L456-K459 PolarHBondContact O-N 2.85Å; L456-I460 WeakPolarHBondContact O-CG1 3.39Å; L456-I460 PolarHBondContact O-N 3.25Å
457S78.7Confident79.4Confident42 Ų4265.6 Ų65.629%0.29433%0.329SS..Hα-helixtrans-61.3-45.3173.4-1790000111.9T453 E454 K459 I460 K461T453-S457 WeakPolarHBondContact O-CB 2.94Å; T453-S457 PolarHBondContact O-N 2.8Å; E454-S457 PolarHBondContact O-N 3.41Å; S457-K459 PolarHBondContact O-N 3.45Å; S457-I460 PolarHBondContact O-N 2.95Å; S457-K461 WeakPolarHBondContact O-CG 3.37Å; S457-K461 PolarHBondContact O-N 2.98Å
458A82.1Confident79.3Confident57 Ų5761 Ų6147%0.47131%0.314SS..Hα-helixtrans-62-39.917500000112.1E454 A462E454-A458 VanDerWaalsContact O-CB 3.27Å; E454-A458 WeakPolarHBondContact O-CB 3.46Å; E454-A458 PolarHBondContact O-N 3.11Å; A458-A462 WeakPolarHBondContact O-CB 3.23Å; A458-A462 PolarHBondContact O-N 3.47Å
459K79.9Confident78.9Confident93 Ų9357.8 Ų57.840%0.40431%0.309SS..Hα-helixtrans-64.4-40.3175-170.7-178.4172.6-153.60111.8E361 L365 M455 L456 S457 A462 M463E361-K459 IonicContact OE1-NZ 2.62Å; E361-K459 PolarHBondContact OE1-NZ 3.41Å; L365-K459 HydrophobicContact CD1-CB 4.16Å; L365-K459 HydrophobicContact CD1-CD 3.54Å; L365-K459 HydrophobicContact CD1-CG 3.72Å; M455-K459 WeakPolarHBondContact O-CB 3.45Å; M455-K459 PolarHBondContact O-N 3.41Å; L456-K459 PolarHBondContact O-N 2.85Å; S457-K459 PolarHBondContact O-N 3.45Å; K459-A462 PolarHBondContact O-N 3.48Å; K459-M463 HydrophobicContact CG-CE 4.46Å; K459-M463 WeakPolarHBondContact O-CG 3.15Å; K459-M463 PolarHBondContact O-N 3.14Å
460I77Confident78.3Confident9 Ų955 Ų555%0.04630%0.299CS..Hα-helixtrans-63.6-55.1174.3-68.4165.5000110.2L365 K366 L369 L456 S457 A462 M463 E464L365-I460 HydrophobicContact CB-CD1 3.76Å; L365-I460 HydrophobicContact CB-CG1 3.53Å; L365-I460 HydrophobicContact CD1-CG1 3.96Å; L365-I460 HydrophobicContact CG-CG1 4.43Å; K366-I460 HydrophobicContact CG-CD1 4.08Å; K366-I460 HydrophobicContact CG-CG2 4.45Å; L369-I460 HydrophobicContact CD1-CD1 3.44Å; L369-I460 VanDerWaalsContact CD1-CD1 3.44Å; L369-I460 HydrophobicContact CG-CD1 4.16Å; L456-I460 WeakPolarHBondContact O-CG1 3.39Å; L456-I460 PolarHBondContact O-N 3.25Å; S457-I460 PolarHBondContact O-N 2.95Å; I460-A462 PolarHBondContact O-N 2.96Å; I460-M463 PolarHBondContact O-N 3.45Å; I460-E464 HydrophobicContact CG2-CG 4.06Å; I460-E464 WeakPolarHBondContact O-CG 3.2Å; I460-E464 PolarHBondContact O-N 3.4Å
461K78.9Confident77.6Confident141 Ų14155.5 Ų55.561%0.61332%0.315SS*.Hα-helixtrans-53.9-40.1177.4-71.4179.8179.4-177.20111.7S457 S465S457-K461 WeakPolarHBondContact O-CG 3.37Å; S457-K461 PolarHBondContact O-N 2.98Å; K461-S465 VanDerWaalsContact O-CB 3.26Å; K461-S465 WeakPolarHBondContact O-CB 3.37Å; K461-S465 PolarHBondContact O-N 3.29Å
462A79.6Confident76.3Confident50 Ų5059.7 Ų59.741%0.41333%0.332SS..Hα-helixtrans-65-39176.600000113.2A458 K459 I460 S465A458-A462 WeakPolarHBondContact O-CB 3.23Å; A458-A462 PolarHBondContact O-N 3.47Å; K459-A462 PolarHBondContact O-N 3.48Å; I460-A462 PolarHBondContact O-N 2.96Å; A462-S465 PolarHBondContact O-OG 2.72Å
463M77.6Confident74.8Confident16 Ų1664.6 Ų64.68%0.07935%0.354CS..Hα-helixtrans-77.2-42.6176.8-68.4-172.2-5100112.7E361 I362 L365 K459 I460 S465 K466E361-M463 HydrophobicContact CG-CE 3.91Å; E361-M463 HydrophobicContact CG-SD 4.03Å; I362-M463 HydrophobicContact CD1-CB 4.06Å; I362-M463 HydrophobicContact CG1-CB 3.87Å; I362-M463 HydrophobicContact CG1-CE 3.86Å; L365-M463 HydrophobicContact CD1-CE 3.33Å; L365-M463 HydrophobicContact CG-CE 4.18Å; K459-M463 HydrophobicContact CG-CE 4.46Å; K459-M463 WeakPolarHBondContact O-CG 3.15Å; K459-M463 PolarHBondContact O-N 3.14Å; I460-M463 PolarHBondContact O-N 3.45Å; M463-S465 PolarHBondContact O-N 3.38Å; M463-K466 WeakPolarHBondContact O-CB 3.48Å; M463-K466 PolarHBondContact O-N 2.91Å
464E77.7Confident73.3Confident73 Ų7370.9 Ų70.934%0.34139%0.385SS..Hα-helixtrans-57.7-38.6173-70.8-177.5145.700111.1I362 K366 I460 K466 L467I362-E464 HydrophobicContact CD1-CG 4.05Å; I362-E464 HydrophobicContact CG1-CG 4.46Å; I362-E464 HydrophobicContact CG2-CG 4.28Å; K366-E464 WeakPolarHBondContact CE-OE1 3.23Å; K366-E464 IonicContact NZ-OE1 2.65Å; K366-E464 PolarHBondContact NZ-OE1 3.24Å; I460-E464 HydrophobicContact CG2-CG 4.06Å; I460-E464 WeakPolarHBondContact O-CG 3.2Å; I460-E464 PolarHBondContact O-N 3.4Å; E464-K466 PolarHBondContact O-N 3.38Å; E464-K466 VanDerWaalsContact O-N 3.1Å; E464-L467 PolarHBondContact O-N 2.88Å
465S79.3Confident71.8Confident57 Ų5769.8 Ų69.840%0.39939%0.385SS..THydrogen-bonded Turntrans-63.7-14175.483.10000114.6K185 K461 A462 M463K185-S465 VanDerWaalsContact CD-O 3.24Å; K185-S465 WeakPolarHBondContact CD-O 3.44Å; K185-S465 WeakPolarHBondContact CE-O 3.36Å; K185-S465 PolarHBondContact NZ-O 3.23Å; K185-S465 PolarHBondContact NZ-OG 2.93Å; K461-S465 VanDerWaalsContact O-CB 3.26Å; K461-S465 WeakPolarHBondContact O-CB 3.37Å; K461-S465 PolarHBondContact O-N 3.29Å; A462-S465 PolarHBondContact O-OG 2.72Å; M463-S465 PolarHBondContact O-N 3.38Å
466K80.9Confident70.5Confident78 Ų7868.9 Ų68.934%0.33938%0.383SS..THydrogen-bonded Turntrans-87.7-19175.6-65.2175.6-175.3178.40112.7V183 F358 M463 E464V183-K466 HydrophobicContact CG1-CB 4.27Å; F358-K466 HydrophobicContact CE2-CD 4.34Å; F358-K466 HydrophobicContact CZ-CD 4.4Å; M463-K466 WeakPolarHBondContact O-CB 3.48Å; M463-K466 PolarHBondContact O-N 2.91Å; E464-K466 PolarHBondContact O-N 3.38Å; E464-K466 VanDerWaalsContact O-N 3.1Å
467L79.4Confident69.3Low20 Ų2073.8 Ų73.811%0.10541%0.405CS..SBendtrans-88.1129.8175.9-61.7178.5000109.1L355 F358 I362 E464L355-L467 HydrophobicContact CG-CD2 4.27Å; F358-L467 HydrophobicContact CB-CD2 4.47Å; F358-L467 HydrophobicContact CD2-CD2 4.38Å; I362-L467 HydrophobicContact CD1-CD1 3.66Å; E464-L467 PolarHBondContact O-N 2.88Å
468L77.6Confident68.4Low27 Ų2774.9 Ų74.914%0.14141%0.41CS..EExtended strand (participates in β ladder)trans-92.1115.8176-62.7168.2000108.2F127 I130 Q137 Y138 V140 K185F127-L468 HydrophobicContact CD1-CD1 4.26Å; F127-L468 HydrophobicContact CE1-CD1 3.75Å; I130-L468 HydrophobicContact CD1-CD1 4.26Å; I130-L468 HydrophobicContact CG2-CB 3.72Å; I130-L468 HydrophobicContact CG2-CD1 4.17Å; Q137-L468 WeakPolarHBondContact CA-O 3.35Å; Y138-L468 PolarHBondContact N-O 3.46Å; Y138-L468 WeakPolarHBondContact O-CB 3.36Å; Y138-L468 PolarHBondContact O-N 3.13Å; V140-L468 HydrophobicContact CG2-CD1 4.19Å; K185-L468 HydrophobicContact CB-CD2 4.07Å; K185-L468 WeakPolarHBondContact O-CD2 3.38Å
469V73.4Confident67.5Low64 Ų6474.5 Ų74.539%0.38840%0.4SS..EExtended strand (participates in β ladder)trans-103120.4174.5-175.20000107.5K472V469-K472 HydrophobicContact CB-CD 4.32Å
470G64Low66.9Low10 Ų1075 Ų7510%0.10340%0.404CS..THydrogen-bonded Turntrans-63.2155.5177.700000113I130 S133I130-G470 VanDerWaalsContact O-CA 3.25Å; I130-G470 WeakPolarHBondContact O-CA 3.28Å; S133-G470 CarbonylContact O-C 3.57Å; S133-G470 WeakPolarHBondContact O-CA 3.31Å
471G63.6Low66.3Low51 Ų5180 Ų8053%0.52643%0.427SS..THydrogen-bonded Turntrans84.43.8176.400000117.1S131 S133 N473S131-G471 PolarHBondContact O-N 3.06Å; S133-G471 PolarHBondContact O-N 3.44Å; G471-N473 PolarHBondContact O-N 3.3Å
472K55.3Low65.9Low161 Ų16178.3 Ų78.370%0.742%0.421SS*.  trans-82.70-175.4-77.9-169.9174.3-176.90117.3V469V469-K472 HydrophobicContact CB-CD 4.32Å
473N48.2Very low65.4Low134 Ų13481.2 Ų81.272%0.71743%0.425SS*.SBendtrans-125.3114.7-178.9-76.6-31.7000112.5G471 V475G471-N473 PolarHBondContact O-N 3.3Å; N473-V475 PolarHBondContact O-N 2.94Å
474I46.4Very low65.5Low154 Ų15485.2 Ų85.279%0.7945%0.445SS*.  trans-71.5118.7176.4-61.8163.1000110.2
475V47.8Very low65.4Low77 Ų7786.3 Ų86.347%0.46745%0.453SS..  -162.286.3122.3-176.40000106.1N473 H477 T478 N479N473-V475 PolarHBondContact O-N 2.94Å; V475-H477 VanDerWaalsContact C-N 3.29Å; V475-H477 PolarHBondContact O-N 3.03Å; V475-T478 VanDerWaalsContact CB-OG1 3.32Å; V475-T478 WeakPolarHBondContact CB-OG1 3.38Å; V475-T478 HydrophobicContact CG1-CG2 4.02Å; V475-T478 WeakPolarHBondContact CG1-OG1 3.42Å; V475-T478 PolarHBondContact O-N 3.24Å; V475-T478 PolarHBondContact O-OG1 3.45Å; V475-N479 PolarHBondContact O-N 2.97Å; V475-N479 VanDerWaalsContact O-N 3.16Å; V475-N479 PolarHBondContact O-ND2 3.27Å
476D55.8Low65.1Low112 Ų11285.3 Ų85.360%0.59944%0.442SS*.Hα-helixtrans-58.1-40.9-170.3-63-45.8000112.7T478 N479 E480D476-T478 PolarHBondContact O-N 3.05Å; D476-N479 PolarHBondContact O-N 2.67Å; D476-E480 WeakPolarHBondContact O-CB 3.43Å; D476-E480 VanDerWaalsContact O-CG 3.31Å; D476-E480 WeakPolarHBondContact O-CG 3.23Å; D476-E480 PolarHBondContact O-N 2.68Å
477H53.1Low65Low123 Ų12385.9 Ų85.957%0.56945%0.446SS*.Hα-helixtrans-67.9-35.7-174.9-145.457.6000114.1V475 E480 Q481V475-H477 VanDerWaalsContact C-N 3.29Å; V475-H477 PolarHBondContact O-N 3.03Å; H477-E480 IonicContact ND1-OE2 3.22Å; H477-E480 PolarHBondContact ND1-OE2 3.18Å; H477-Q481 WeakPolarHBondContact O-CB 3.28Å; H477-Q481 VanDerWaalsContact O-CG 3.28Å; H477-Q481 WeakPolarHBondContact O-CG 3.25Å; H477-Q481 PolarHBondContact O-N 3.32Å
478T59.1Low65Low65 Ų6589.7 Ų89.740%0.39946%0.462SS..Hα-helixtrans-74.7-35.1173.151.20000111.5V475 D476 E480 Q481 Q482V475-T478 VanDerWaalsContact CB-OG1 3.32Å; V475-T478 WeakPolarHBondContact CB-OG1 3.38Å; V475-T478 HydrophobicContact CG1-CG2 4.02Å; V475-T478 WeakPolarHBondContact CG1-OG1 3.42Å; V475-T478 PolarHBondContact O-N 3.24Å; V475-T478 PolarHBondContact O-OG1 3.45Å; D476-T478 PolarHBondContact O-N 3.05Å; T478-E480 VanDerWaalsContact C-N 3.34Å; T478-Q481 PolarHBondContact O-N 3.3Å; T478-Q482 WeakPolarHBondContact O-CB 3.33Å; T478-Q482 VanDerWaalsContact O-CG 3.3Å; T478-Q482 WeakPolarHBondContact O-CG 3.45Å; T478-Q482 PolarHBondContact O-N 3.39Å
479N63.4Low65.1Low50 Ų5093.4 Ų93.427%0.26747%0.474SS..Hα-helixtrans-65.6-37.6176.2-71.2-17.8000111.7R132 V475 D476 K483R132-N479 PolarHBondContact NH2-O 3.33Å; V475-N479 PolarHBondContact O-N 2.97Å; V475-N479 VanDerWaalsContact O-N 3.16Å; V475-N479 PolarHBondContact O-ND2 3.27Å; D476-N479 PolarHBondContact O-N 2.67Å; N479-K483 WeakPolarHBondContact O-CB 3.28Å; N479-K483 PolarHBondContact O-N 2.87Å
480E66.8Low65.2Low103 Ų10393.4 Ų93.448%0.48147%0.47SS..Hα-helixtrans-66.8-49172.7-76.7178.5153.500112.1D476 H477 T478 Q482 K483 I484D476-E480 WeakPolarHBondContact O-CB 3.43Å; D476-E480 VanDerWaalsContact O-CG 3.31Å; D476-E480 WeakPolarHBondContact O-CG 3.23Å; D476-E480 PolarHBondContact O-N 2.68Å; H477-E480 IonicContact ND1-OE2 3.22Å; H477-E480 PolarHBondContact ND1-OE2 3.18Å; T478-E480 VanDerWaalsContact C-N 3.34Å; E480-Q482 VanDerWaalsContact C-N 3.31Å; E480-Q482 PolarHBondContact O-N 3.42Å; E480-K483 WeakPolarHBondContact O-CA 3.39Å; E480-K483 VanDerWaalsContact O-CB 3.26Å; E480-K483 WeakPolarHBondContact O-CB 3.25Å; E480-K483 PolarHBondContact O-N 2.97Å; E480-I484 WeakPolarHBondContact O-CG1 3.26Å; E480-I484 PolarHBondContact O-N 3.16Å
481Q65.4Low66Low114 Ų11497.6 Ų97.653%0.53349%0.486SS..Hα-helixtrans-59.8-41.9176.4-73.81771000111.7H477 T478 K483 I484 L485H477-Q481 WeakPolarHBondContact O-CB 3.28Å; H477-Q481 VanDerWaalsContact O-CG 3.28Å; H477-Q481 WeakPolarHBondContact O-CG 3.25Å; H477-Q481 PolarHBondContact O-N 3.32Å; T478-Q481 PolarHBondContact O-N 3.3Å; Q481-K483 VanDerWaalsContact C-N 3.3Å; Q481-K483 PolarHBondContact O-N 2.7Å; Q481-I484 PolarHBondContact O-N 2.89Å; Q481-L485 WeakPolarHBondContact O-CB 3.45Å; Q481-L485 PolarHBondContact O-N 2.75Å
482Q68.6Low66.9Low106 Ų10699.4 Ų99.450%0.49548%0.483SS..Hα-helixtrans-64.1-33.7171.6-74177.9-9.600112.3T478 E480 L485 E486T478-Q482 WeakPolarHBondContact O-CB 3.33Å; T478-Q482 VanDerWaalsContact O-CG 3.3Å; T478-Q482 WeakPolarHBondContact O-CG 3.45Å; T478-Q482 PolarHBondContact O-N 3.39Å; E480-Q482 VanDerWaalsContact C-N 3.31Å; E480-Q482 PolarHBondContact O-N 3.42Å; Q482-L485 PolarHBondContact O-N 3.07Å; Q482-E486 VanDerWaalsContact O-CB 3.22Å; Q482-E486 WeakPolarHBondContact O-CB 3.32Å; Q482-E486 PolarHBondContact O-N 3Å
483K71.1Confident67.9Low111 Ų11192.4 Ų92.448%0.48346%0.456SS..Hα-helixtrans-66.6-46.2178.3-161.5174.6-178.4177.60110.9R132 N479 E480 Q481 E486 Q487R132-K483 VanDerWaalsContact NH2-CB 3.26Å; N479-K483 WeakPolarHBondContact O-CB 3.28Å; N479-K483 PolarHBondContact O-N 2.87Å; E480-K483 WeakPolarHBondContact O-CA 3.39Å; E480-K483 VanDerWaalsContact O-CB 3.26Å; E480-K483 WeakPolarHBondContact O-CB 3.25Å; E480-K483 PolarHBondContact O-N 2.97Å; Q481-K483 VanDerWaalsContact C-N 3.3Å; Q481-K483 PolarHBondContact O-N 2.7Å; K483-E486 PolarHBondContact O-N 3.47Å; K483-Q487 VanDerWaalsContact O-CB 3.32Å; K483-Q487 WeakPolarHBondContact O-CB 3.36Å; K483-Q487 VanDerWaalsContact O-CG 3.23Å; K483-Q487 WeakPolarHBondContact O-CG 3.17Å; K483-Q487 PolarHBondContact O-N 2.89Å
484I77.9Confident69.5Low99 Ų9991 Ų9151%0.50844%0.444SS..Hα-helixtrans-62.8-44.7176-63.9163.3000109.8E480 Q481 E486 K488E480-I484 WeakPolarHBondContact O-CG1 3.26Å; E480-I484 PolarHBondContact O-N 3.16Å; Q481-I484 PolarHBondContact O-N 2.89Å; I484-E486 PolarHBondContact O-N 2.72Å; I484-K488 HydrophobicContact CG2-CG 4.41Å; I484-K488 WeakPolarHBondContact O-CB 3.3Å; I484-K488 WeakPolarHBondContact O-CG 3.44Å; I484-K488 PolarHBondContact O-N 3.05Å
485L76.1Confident71.2Confident97 Ų9789.9 Ų89.951%0.50844%0.436SS..Hα-helixtrans-62.4-42.3178.1-175.864.6000112.4Q481 Q482 K488 R489Q481-L485 WeakPolarHBondContact O-CB 3.45Å; Q481-L485 PolarHBondContact O-N 2.75Å; Q482-L485 PolarHBondContact O-N 3.07Å; L485-K488 PolarHBondContact O-N 3.38Å; L485-R489 WeakPolarHBondContact O-CG 3.38Å; L485-R489 PolarHBondContact O-N 2.93Å
486E74.1Confident72.6Confident36 Ų3691 Ų9117%0.16844%0.435CS..Hα-helixtrans-69.9-43.6179.2-173.1167.8-136.700112.1R78 R132 Q482 K483 I484 K488 R489 Q490R78-E486 IonicContact CZ-OE1 3.6Å; R78-E486 IonicContact NH1-OE1 3.82Å; R78-E486 PolarHBondContact NH1-OE1 2.98Å; R78-E486 IonicContact NH2-OE1 3.88Å; R78-E486 PolarHBondContact NH2-OE1 3.3Å; R132-E486 IonicContact CZ-OE2 3.07Å; R132-E486 IonicContact NH1-OE2 3.7Å; R132-E486 PolarHBondContact NH1-OE2 3.13Å; R132-E486 IonicContact NH2-OE2 2.66Å; Q482-E486 VanDerWaalsContact O-CB 3.22Å; Q482-E486 WeakPolarHBondContact O-CB 3.32Å; Q482-E486 PolarHBondContact O-N 3Å; K483-E486 PolarHBondContact O-N 3.47Å; I484-E486 PolarHBondContact O-N 2.72Å; E486-K488 VanDerWaalsContact C-N 3.33Å; E486-K488 PolarHBondContact O-N 2.95Å; E486-R489 WeakPolarHBondContact O-CB 3.49Å; E486-R489 PolarHBondContact O-N 3.27Å; E486-Q490 WeakPolarHBondContact O-CG 3.29Å; E486-Q490 PolarHBondContact O-N 3.29Å
487Q78Confident73.7Confident90 Ų9091 Ų9142%0.42143%0.426SS..Hα-helixtrans-59.1-43.2171.6-75174.7-24.400111.4K483 R489 Q490 E491K483-Q487 VanDerWaalsContact O-CB 3.32Å; K483-Q487 WeakPolarHBondContact O-CB 3.36Å; K483-Q487 VanDerWaalsContact O-CG 3.23Å; K483-Q487 WeakPolarHBondContact O-CG 3.17Å; K483-Q487 PolarHBondContact O-N 2.89Å; Q487-R489 VanDerWaalsContact C-N 3.34Å; Q487-R489 PolarHBondContact O-N 2.92Å; Q487-Q490 PolarHBondContact O-N 3.37Å; Q487-E491 WeakPolarHBondContact O-CG 3.49Å; Q487-E491 PolarHBondContact O-N 3.19Å
488K80.2Confident74.9Confident99 Ų9992 Ų9243%0.4343%0.425SS..Hα-helixtrans-65.1-35.5175.9-70.5-71.8161.8-132.20112.5I484 L485 E486 E491 I492I484-K488 HydrophobicContact CG2-CG 4.41Å; I484-K488 WeakPolarHBondContact O-CB 3.3Å; I484-K488 WeakPolarHBondContact O-CG 3.44Å; I484-K488 PolarHBondContact O-N 3.05Å; L485-K488 PolarHBondContact O-N 3.38Å; E486-K488 VanDerWaalsContact C-N 3.33Å; E486-K488 PolarHBondContact O-N 2.95Å; K488-E491 WeakPolarHBondContact CD-OE2 3.39Å; K488-E491 IonicContact NZ-OE1 3.34Å; K488-E491 PolarHBondContact NZ-OE1 3.26Å; K488-E491 IonicContact NZ-OE2 3.17Å; K488-E491 PolarHBondContact NZ-OE2 3.05Å; K488-I492 WeakPolarHBondContact O-CB 3.08Å; K488-I492 WeakPolarHBondContact O-CD1 3.44Å; K488-I492 WeakPolarHBondContact O-CG1 3.48Å; K488-I492 PolarHBondContact O-N 2.83Å
489R78.6Confident75.9Confident105 Ų10595 Ų9540%0.39644%0.435SS..Hα-helixtrans-66-42.5171.8-73.5171.7178.9-146.811.3112.2D74 L485 E486 Q487 I492 A493D74-R489 IonicContact OD2-CZ 2.73Å; D74-R489 IonicContact OD2-NH1 2.59Å; D74-R489 PolarHBondContact OD2-NH1 3.19Å; L485-R489 WeakPolarHBondContact O-CG 3.38Å; L485-R489 PolarHBondContact O-N 2.93Å; E486-R489 WeakPolarHBondContact O-CB 3.49Å; E486-R489 PolarHBondContact O-N 3.27Å; Q487-R489 VanDerWaalsContact C-N 3.34Å; Q487-R489 PolarHBondContact O-N 2.92Å; R489-I492 PolarHBondContact O-N 2.93Å; R489-A493 WeakPolarHBondContact O-CB 3.43Å; R489-A493 PolarHBondContact O-N 3.08Å
490Q75.6Confident76.7Confident65 Ų6594 Ų9430%0.30443%0.427SS..Hα-helixtrans-61.7-47.8174.7-74.2173.1-31.300111.4E486 Q487 I492 A493 E494E486-Q490 WeakPolarHBondContact O-CG 3.29Å; E486-Q490 PolarHBondContact O-N 3.29Å; Q487-Q490 PolarHBondContact O-N 3.37Å; Q490-I492 VanDerWaalsContact C-N 3.34Å; Q490-I492 PolarHBondContact O-N 2.92Å; Q490-A493 PolarHBondContact O-N 3.26Å; Q490-E494 WeakPolarHBondContact O-CB 3.32Å; Q490-E494 PolarHBondContact O-N 2.98Å
491E82Confident77.3Confident97 Ų9792.4 Ų92.445%0.45342%0.419SS..Hα-helixtrans-55.5-46.5174.3-75.2174.4-158.400111.8Q487 K488 E494 Q495Q487-E491 WeakPolarHBondContact O-CG 3.49Å; Q487-E491 PolarHBondContact O-N 3.19Å; K488-E491 WeakPolarHBondContact CD-OE2 3.39Å; K488-E491 IonicContact NZ-OE1 3.34Å; K488-E491 PolarHBondContact NZ-OE1 3.26Å; K488-E491 IonicContact NZ-OE2 3.17Å; K488-E491 PolarHBondContact NZ-OE2 3.05Å; E491-E494 PolarHBondContact O-N 3.14Å; E491-Q495 WeakPolarHBondContact O-CB 3.46Å; E491-Q495 PolarHBondContact O-N 2.87Å
492I81.1Confident77.9Confident89 Ų8991.8 Ų91.846%0.45642%0.419SS..Hα-helixtrans-64.8-41.3178.1-70.2164.1000111.5K488 R489 Q490 Q495 K496K488-I492 WeakPolarHBondContact O-CB 3.08Å; K488-I492 WeakPolarHBondContact O-CD1 3.44Å; K488-I492 WeakPolarHBondContact O-CG1 3.48Å; K488-I492 PolarHBondContact O-N 2.83Å; R489-I492 PolarHBondContact O-N 2.93Å; Q490-I492 VanDerWaalsContact C-N 3.34Å; Q490-I492 PolarHBondContact O-N 2.92Å; I492-Q495 PolarHBondContact O-N 3.36Å; I492-K496 HydrophobicContact CG2-CD 4.31Å; I492-K496 WeakPolarHBondContact O-CB 3.17Å; I492-K496 WeakPolarHBondContact O-CG 3.41Å; I492-K496 PolarHBondContact O-N 3.14Å
493A77.6Confident78.3Confident15 Ų1590.5 Ų90.512%0.12441%0.413CS..Hα-helixtrans-66.5-44.6178.200000111.7R489 Q490 R497R489-A493 WeakPolarHBondContact O-CB 3.43Å; R489-A493 PolarHBondContact O-N 3.08Å; Q490-A493 PolarHBondContact O-N 3.26Å; A493-R497 WeakPolarHBondContact O-CB 3.38Å; A493-R497 PolarHBondContact O-N 2.84Å
494E80.8Confident78.4Confident103 Ų10387.9 Ų87.948%0.48140%0.402SS..Hα-helixtrans-63.8-42.9173.5-77.7-160.9-160.900112.3Q490 E491 R497 R498Q490-E494 WeakPolarHBondContact O-CB 3.32Å; Q490-E494 PolarHBondContact O-N 2.98Å; E491-E494 PolarHBondContact O-N 3.14Å; E494-R497 PolarHBondContact O-N 2.99Å; E494-R498 WeakPolarHBondContact O-CB 3.43Å; E494-R498 VanDerWaalsContact O-CG 3.29Å; E494-R498 WeakPolarHBondContact O-CG 3.38Å; E494-R498 PolarHBondContact O-N 3.49Å; E494-R498 IonicContact OE2-CZ 2.79Å; E494-R498 IonicContact OE2-NE 4Å; E494-R498 IonicContact OE2-NH2 3.84Å; E494-R498 PolarHBondContact OE2-NH2 3.27Å
495Q81.3Confident78.4Confident132 Ų13289.5 Ų89.562%0.61741%0.408SS*.Hα-helixtrans-61.2-48.7177.9-176.3177.32.200110.8E491 I492 R497 R498 E499E491-Q495 WeakPolarHBondContact O-CB 3.46Å; E491-Q495 PolarHBondContact O-N 2.87Å; I492-Q495 PolarHBondContact O-N 3.36Å; Q495-R497 VanDerWaalsContact C-N 3.32Å; Q495-R497 PolarHBondContact O-N 3.35Å; Q495-R498 PolarHBondContact O-N 3.29Å; Q495-E499 VanDerWaalsContact O-CB 3.28Å; Q495-E499 WeakPolarHBondContact O-CB 3.49Å; Q495-E499 PolarHBondContact O-N 3.37Å
496K78.5Confident78.2Confident100 Ų10089.5 Ų89.544%0.43541%0.406SS..Hα-helixtrans-56.7-45.7174-78.1177.3176.5-178.20111.6I492 E499 R500I492-K496 HydrophobicContact CG2-CD 4.31Å; I492-K496 WeakPolarHBondContact O-CB 3.17Å; I492-K496 WeakPolarHBondContact O-CG 3.41Å; I492-K496 PolarHBondContact O-N 3.14Å; K496-E499 WeakPolarHBondContact O-CB 3.45Å; K496-E499 PolarHBondContact O-N 3.48Å; K496-R500 WeakPolarHBondContact O-CG 3.42Å; K496-R500 PolarHBondContact O-N 2.95Å
497R77.9Confident78.1Confident112 Ų11291 Ų9142%0.42341%0.413SS..Hα-helixtrans-61.8-48.5179.1-178.4-178.7163.5-161.4-10.5111.6A493 E494 Q495 E499 R500 E501A493-R497 WeakPolarHBondContact O-CB 3.38Å; A493-R497 PolarHBondContact O-N 2.84Å; E494-R497 PolarHBondContact O-N 2.99Å; Q495-R497 VanDerWaalsContact C-N 3.32Å; Q495-R497 PolarHBondContact O-N 3.35Å; R497-E499 VanDerWaalsContact C-N 3.32Å; R497-E499 PolarHBondContact O-N 3.25Å; R497-R500 PolarHBondContact O-N 3.29Å; R497-E501 IonicContact CZ-OE1 2.7Å; R497-E501 IonicContact NE-OE1 2.77Å; R497-E501 PolarHBondContact NE-OE1 2.94Å; R497-E501 IonicContact NH2-OE1 3.8Å; R497-E501 PolarHBondContact NH2-OE1 3.32Å; R497-E501 WeakPolarHBondContact O-CG 3.43Å; R497-E501 PolarHBondContact O-N 2.99Å
498R79.3Confident77.6Confident145 Ų14589.7 Ų89.755%0.54741%0.414SS..Hα-helixtrans-63.2-38.2177.3-67.4176.9-160.3-169.17.4111.5E494 Q495 E501 I502E494-R498 WeakPolarHBondContact O-CB 3.43Å; E494-R498 VanDerWaalsContact O-CG 3.29Å; E494-R498 WeakPolarHBondContact O-CG 3.38Å; E494-R498 PolarHBondContact O-N 3.49Å; E494-R498 IonicContact OE2-CZ 2.79Å; E494-R498 IonicContact OE2-NE 4Å; E494-R498 IonicContact OE2-NH2 3.84Å; E494-R498 PolarHBondContact OE2-NH2 3.27Å; Q495-R498 PolarHBondContact O-N 3.29Å; R498-E501 PolarHBondContact O-N 2.76Å; R498-I502 VanDerWaalsContact O-CB 3.31Å; R498-I502 WeakPolarHBondContact O-CB 3.38Å; R498-I502 WeakPolarHBondContact O-CD1 3.02Å; R498-I502 WeakPolarHBondContact O-CG1 3.34Å; R498-I502 PolarHBondContact O-N 3.33Å
499E80.3Confident76.8Confident128 Ų12892.7 Ų92.760%0.59842%0.423SS*.Hα-helixtrans-60.4-44.5174-173.9-177.1175.300111.1Q495 K496 R497 Q503Q495-E499 VanDerWaalsContact O-CB 3.28Å; Q495-E499 WeakPolarHBondContact O-CB 3.49Å; Q495-E499 PolarHBondContact O-N 3.37Å; K496-E499 WeakPolarHBondContact O-CB 3.45Å; K496-E499 PolarHBondContact O-N 3.48Å; R497-E499 VanDerWaalsContact C-N 3.32Å; R497-E499 PolarHBondContact O-N 3.25Å; E499-Q503 VanDerWaalsContact O-CB 3.29Å; E499-Q503 WeakPolarHBondContact O-CB 3.24Å; E499-Q503 PolarHBondContact O-N 2.81Å
500R79.4Confident76.1Confident27 Ų2791.7 Ų91.710%0.10243%0.425CS..Hα-helixtrans-65.7-45.4173.9-62.6-165-151102-0.4112.8V36 K37 E75 K496 R497 I502 Q503 Q504V36-R500 WeakPolarHBondContact O-CD 3.46Å; V36-R500 PolarHBondContact O-NE 2.92Å; V36-R500 VanDerWaalsContact O-NE 3.08Å; K37-R500 WeakPolarHBondContact O-CD 3.49Å; K37-R500 VanDerWaalsContact O-CG 3.27Å; K37-R500 WeakPolarHBondContact O-CG 3.38Å; E75-R500 IonicContact OE1-CZ 3.83Å; E75-R500 IonicContact OE1-NH1 3.68Å; E75-R500 PolarHBondContact OE1-NH1 3.34Å; E75-R500 IonicContact OE1-NH2 3.82Å; E75-R500 PolarHBondContact OE1-NH2 2.82Å; E75-R500 IonicContact OE2-CZ 2.6Å; E75-R500 IonicContact OE2-NH1 2.66Å; E75-R500 IonicContact OE2-NH2 3.72Å; E75-R500 PolarHBondContact OE2-NH2 2.59Å; K496-R500 WeakPolarHBondContact O-CG 3.42Å; K496-R500 PolarHBondContact O-N 2.95Å; R497-R500 PolarHBondContact O-N 3.29Å; R500-I502 VanDerWaalsContact C-N 3.3Å; R500-I502 PolarHBondContact O-N 2.93Å; R500-Q503 PolarHBondContact O-N 2.9Å; R500-Q504 WeakPolarHBondContact O-CB 3.34Å; R500-Q504 WeakPolarHBondContact O-CG 3.31Å; R500-Q504 PolarHBondContact O-N 3.02Å
501E78.6Confident75.6Confident70 Ų7092.9 Ų92.933%0.32743%0.431SS..Hα-helixtrans-60.7-41.3178.2-73.7175.7-179.400111R497 R498 Q505R497-E501 IonicContact CZ-OE1 2.7Å; R497-E501 IonicContact NE-OE1 2.77Å; R497-E501 PolarHBondContact NE-OE1 2.94Å; R497-E501 IonicContact NH2-OE1 3.8Å; R497-E501 PolarHBondContact NH2-OE1 3.32Å; R497-E501 WeakPolarHBondContact O-CG 3.43Å; R497-E501 PolarHBondContact O-N 2.99Å; R498-E501 PolarHBondContact O-N 2.76Å; E501-Q505 WeakPolarHBondContact O-CB 3.22Å; E501-Q505 VanDerWaalsContact O-CG 3.26Å; E501-Q505 WeakPolarHBondContact O-CG 3.37Å; E501-Q505 PolarHBondContact O-N 3.05Å
502I79.4Confident74.5Confident101 Ų10193.1 Ų93.152%0.51843%0.432SS..Hα-helixtrans-66.8-43.5173.6-69.7165.6000110.9R498 R500 Q505 M506R498-I502 VanDerWaalsContact O-CB 3.31Å; R498-I502 WeakPolarHBondContact O-CB 3.38Å; R498-I502 WeakPolarHBondContact O-CD1 3.02Å; R498-I502 WeakPolarHBondContact O-CG1 3.34Å; R498-I502 PolarHBondContact O-N 3.33Å; R500-I502 VanDerWaalsContact C-N 3.3Å; R500-I502 PolarHBondContact O-N 2.93Å; I502-Q505 CarbonylContact O-C 3.6Å; I502-Q505 PolarHBondContact O-N 3.25Å; I502-M506 HydrophobicContact CG2-CG 3.99Å; I502-M506 VanDerWaalsContact O-CB 3.31Å; I502-M506 WeakPolarHBondContact O-CB 3.35Å; I502-M506 WeakPolarHBondContact O-CG 3.46Å; I502-M506 PolarHBondContact O-N 3.28Å
503Q76.6Confident73.3Confident79 Ų7991.2 Ų91.237%0.36942%0.424SS..Hα-helixtrans-64.9-42.1179.5-175.961.43000111.9L38 E499 R500 M506 E507L38-Q503 HydrophobicContact CD2-CG 3.78Å; E499-Q503 VanDerWaalsContact O-CB 3.29Å; E499-Q503 WeakPolarHBondContact O-CB 3.24Å; E499-Q503 PolarHBondContact O-N 2.81Å; R500-Q503 PolarHBondContact O-N 2.9Å; Q503-M506 PolarHBondContact O-N 2.8Å; Q503-E507 PolarHBondContact NE2-OE1 2.73Å; Q503-E507 PolarHBondContact O-N 3.05Å
504Q74.1Confident72.2Confident57 Ų5795.1 Ų95.127%0.26644%0.443SS..Hα-helixtrans-62.4-42.2173.3-73.3176.2-8.400111.6L38 R500 S508L38-Q504 PolarHBondContact O-NE2 3.08Å; R500-Q504 WeakPolarHBondContact O-CB 3.34Å; R500-Q504 WeakPolarHBondContact O-CG 3.31Å; R500-Q504 PolarHBondContact O-N 3.02Å; Q504-S508 WeakPolarHBondContact O-CB 2.94Å; Q504-S508 PolarHBondContact O-N 2.66Å
505Q76.4Confident70.9Confident133 Ų13395 Ų9562%0.62144%0.442SS*.Hα-helixtrans-67.9-37.5175-75.5177.731.400112.4E501 I502 R509E501-Q505 WeakPolarHBondContact O-CB 3.22Å; E501-Q505 VanDerWaalsContact O-CG 3.26Å; E501-Q505 WeakPolarHBondContact O-CG 3.37Å; E501-Q505 PolarHBondContact O-N 3.05Å; I502-Q505 CarbonylContact O-C 3.6Å; I502-Q505 PolarHBondContact O-N 3.25Å; Q505-R509 WeakPolarHBondContact O-CB 3.36Å; Q505-R509 PolarHBondContact O-N 3.24Å
506M72.9Confident69.5Low96 Ų9696.1 Ų96.147%0.47345%0.451SS..Hα-helixtrans-63.2-48.1174.7-73.3-94.3-69.900110.1I502 Q503 R509 D510I502-M506 HydrophobicContact CG2-CG 3.99Å; I502-M506 VanDerWaalsContact O-CB 3.31Å; I502-M506 WeakPolarHBondContact O-CB 3.35Å; I502-M506 WeakPolarHBondContact O-CG 3.46Å; I502-M506 PolarHBondContact O-N 3.28Å; Q503-M506 PolarHBondContact O-N 2.8Å; M506-R509 CarbonylContact O-C 3.56Å; M506-R509 PolarHBondContact O-N 3.46Å; M506-D510 WeakPolarHBondContact O-CB 3.3Å; M506-D510 PolarHBondContact O-N 3.4Å
507E70.6Confident68.1Low68 Ų6899.5 Ų99.532%0.31847%0.466SS..Hα-helixtrans-63.2-44.3176.2-75.8179.4-174.500112.6L38 Q503 R509 D510 E511L38-E507 WeakPolarHBondContact CD2-OE1 3.39Å; Q503-E507 PolarHBondContact NE2-OE1 2.73Å; Q503-E507 PolarHBondContact O-N 3.05Å; E507-R509 VanDerWaalsContact C-N 3.31Å; E507-R509 PolarHBondContact O-N 2.77Å; E507-D510 PolarHBondContact O-N 2.7Å; E507-E511 WeakPolarHBondContact O-CG 3.31Å; E507-E511 PolarHBondContact O-N 3.37Å
508S68.3Low67.1Low62 Ų6296.7 Ų96.743%0.43446%0.458SS..Hα-helixtrans-60.4-42.2175-167.40000111.6Q504 E511 E512Q504-S508 WeakPolarHBondContact O-CB 2.94Å; Q504-S508 PolarHBondContact O-N 2.66Å; S508-E511 PolarHBondContact O-N 3.47Å; S508-E512 WeakPolarHBondContact O-CG 3.12Å; S508-E512 PolarHBondContact O-N 3Å
509R64.4Low66.2Low162 Ų16296.5 Ų96.561%0.61147%0.473SS*.Hα-helixtrans-77.3-27.6-179.3-171177.4-178.486.6-4.5112.3Q505 M506 E507 T513Q505-R509 WeakPolarHBondContact O-CB 3.36Å; Q505-R509 PolarHBondContact O-N 3.24Å; M506-R509 CarbonylContact O-C 3.56Å; M506-R509 PolarHBondContact O-N 3.46Å; E507-R509 VanDerWaalsContact C-N 3.31Å; E507-R509 PolarHBondContact O-N 2.77Å; R509-T513 HydrophobicContact CG-CG2 4.21Å; R509-T513 VanDerWaalsContact O-CB 3.23Å; R509-T513 WeakPolarHBondContact O-CB 3.25Å; R509-T513 WeakPolarHBondContact O-CG2 3.07Å; R509-T513 PolarHBondContact O-N 3.49Å; R509-T513 PolarHBondContact O-OG1 3.03Å
510D63.9Low65.5Low84 Ų8494 Ų9445%0.44946%0.459SS..Hα-helixtrans-72.5-37.8171.4-77.2-13.9000109.7M506 E507 L514M506-D510 WeakPolarHBondContact O-CB 3.3Å; M506-D510 PolarHBondContact O-N 3.4Å; E507-D510 PolarHBondContact O-N 2.7Å; D510-L514 WeakPolarHBondContact O-CB 3.44Å; D510-L514 WeakPolarHBondContact O-CD1 3.28Å; D510-L514 VanDerWaalsContact O-CG 3.23Å; D510-L514 WeakPolarHBondContact O-CG 3.34Å; D510-L514 PolarHBondContact O-N 2.97Å
511E63.2Low64.9Low91 Ų9197.9 Ų97.943%0.42549%0.49SS..Hα-helixtrans-59.7-52.5166.5-70.8-155.3153.100111.3E507 S508 T513 L514 E515 K540E507-E511 WeakPolarHBondContact O-CG 3.31Å; E507-E511 PolarHBondContact O-N 3.37Å; S508-E511 PolarHBondContact O-N 3.47Å; E511-T513 PolarHBondContact O-N 2.83Å; E511-L514 PolarHBondContact O-N 3.42Å; E511-E515 WeakPolarHBondContact O-CG 3.43Å; E511-E515 PolarHBondContact O-N 3.42Å; E511-K540 IonicContact OE1-NZ 3.6Å; E511-K540 IonicContact OE2-NZ 3.11Å; E511-K540 PolarHBondContact OE2-NZ 2.99Å
512E60.8Low64.8Low101 Ų10197.2 Ų97.247%0.47249%0.493SS..Hα-helixtrans-63-34.4178.8-72.9172-167.500113.9S508 E515 L516S508-E512 WeakPolarHBondContact O-CG 3.12Å; S508-E512 PolarHBondContact O-N 3Å; E512-E515 WeakPolarHBondContact O-CB 3.39Å; E512-E515 PolarHBondContact O-N 2.94Å; E512-L516 PolarHBondContact O-N 3.25Å
513T55Low64.5Low49 Ų4998.7 Ų98.730%0.30150%0.501SS..Hα-helixtrans-86.1-27.1-18058.40000112.8R509 E511 L516 K517R509-T513 HydrophobicContact CG-CG2 4.21Å; R509-T513 VanDerWaalsContact O-CB 3.23Å; R509-T513 WeakPolarHBondContact O-CB 3.25Å; R509-T513 WeakPolarHBondContact O-CG2 3.07Å; R509-T513 PolarHBondContact O-N 3.49Å; R509-T513 PolarHBondContact O-OG1 3.03Å; E511-T513 PolarHBondContact O-N 2.83Å; T513-L516 PolarHBondContact O-N 3.05Å; T513-K517 WeakPolarHBondContact O-CB 3.41Å; T513-K517 PolarHBondContact O-N 2.66Å
514L54.9Low64.4Low97 Ų97100.9 Ų100.951%0.50851%0.512SS..Hα-helixtrans-61.9-33.2159.4-81162.8000110.9D510 E511 K533D510-L514 WeakPolarHBondContact O-CB 3.44Å; D510-L514 WeakPolarHBondContact O-CD1 3.28Å; D510-L514 VanDerWaalsContact O-CG 3.23Å; D510-L514 WeakPolarHBondContact O-CG 3.34Å; D510-L514 PolarHBondContact O-N 2.97Å; E511-L514 PolarHBondContact O-N 3.42Å; L514-K533 VanDerWaalsContact O-CE 3.24Å; L514-K533 WeakPolarHBondContact O-CE 3.22Å; L514-K533 PolarHBondContact O-NZ 3.28Å
515E54.1Low64.5Low102 Ų102101.8 Ų101.848%0.47752%0.516SS..Hα-helixtrans-66.7-41.4173.1-75.2175.1-176.200112.3E511 E512 K533E511-E515 WeakPolarHBondContact O-CG 3.43Å; E511-E515 PolarHBondContact O-N 3.42Å; E512-E515 WeakPolarHBondContact O-CB 3.39Å; E512-E515 PolarHBondContact O-N 2.94Å; E515-K533 PolarHBondContact O-NZ 3.43Å
516L50.3Low64.5Low154 Ų15497.9 Ų97.981%0.80650%0.498SS*.Hα-helixtrans-89.6-32.5-177.2-102.497.1000117.8E512 T513E512-L516 PolarHBondContact O-N 3.25Å; T513-L516 PolarHBondContact O-N 3.05Å
517K50.2Low64.7Low172 Ų17296.8 Ų96.875%0.74850%0.496SS*.  trans-107.155.8-166.2-71.8-173.2173.6178.80114.7T513T513-K517 WeakPolarHBondContact O-CB 3.41Å; T513-K517 PolarHBondContact O-N 2.66Å
518E55.5Low65Low52 Ų5297.4 Ų97.424%0.24350%0.501CS..  trans-118.189.5168.3-70.4173.114500110.2Y520 I529 K533E518-Y520 HydrophobicContact CB-CD1 4.36Å; E518-Y520 HydrophobicContact CB-CE1 3.77Å; E518-Y520 WeakPolarHBondContact O-CE2 3.43Å; E518-Y520 PolarHBondContact O-N 3.38Å; E518-I529 WeakPolarHBondContact OE1-CG2 3.19Å; E518-I529 WeakPolarHBondContact OE2-CG2 3.45Å; E518-K533 WeakPolarHBondContact OE2-CE 3.29Å; E518-K533 IonicContact OE2-NZ 3.23Å; E518-K533 PolarHBondContact OE2-NZ 3.11Å
519T60.7Low65.3Low141 Ų14195.8 Ų95.887%0.86549%0.487SS*.  trans-74.9107.2162.247.10000108.3
520Y66.3Low65.9Low76 Ų7693 Ų9330%0.29848%0.48SS..  trans-73.6129.7-178.1-46.8-72.7000111.1E518 E526 I529E518-Y520 HydrophobicContact CB-CD1 4.36Å; E518-Y520 HydrophobicContact CB-CE1 3.77Å; E518-Y520 WeakPolarHBondContact O-CE2 3.43Å; E518-Y520 PolarHBondContact O-N 3.38Å; Y520-E526 VanDerWaalsContact CD1-CA 3.43Å; Y520-E526 HydrophobicContact CD1-CB 3.71Å; Y520-E526 HydrophobicContact CD1-CG 4.01Å; Y520-E526 HydrophobicContact CD2-CB 3.93Å; Y520-E526 HydrophobicContact CD2-CG 3.63Å; Y520-E526 HydrophobicContact CE1-CB 4.22Å; Y520-E526 HydrophobicContact CE1-CG 4.09Å; Y520-E526 HydrophobicContact CE2-CB 4.45Å; Y520-E526 HydrophobicContact CE2-CG 3.76Å; Y520-E526 HydrophobicContact CG-CB 3.53Å; Y520-E526 HydrophobicContact CG-CG 3.77Å; Y520-I529 HydrophobicContact CD1-CD1 4.33Å; Y520-I529 HydrophobicContact CE1-CB 4.23Å; Y520-I529 HydrophobicContact CE1-CD1 4.4Å; Y520-I529 HydrophobicContact CE1-CG2 3.99Å
521S67.5Low66.7Low108 Ų10891.8 Ų91.876%0.75548%0.476SS*.SBendtrans-84.4-14.3174.671.90000112.9Q525S521-Q525 PolarHBondContact OG-OE1 2.97Å
522S75Confident67.4Low56 Ų5694.3 Ų94.339%0.39249%0.485SS..SBendtrans-153.4155.3174.366.30000112.1Q524 Q525 E526S522-Q524 PolarHBondContact O-N 3.4Å; S522-Q525 PolarHBondContact O-N 3.16Å; S522-Q525 WeakPolarHBondContact OG-CB 3.3Å; S522-Q525 PolarHBondContact OG-N 3.46Å; S522-E526 PolarHBondContact O-N 2.86Å
523L72.9Confident67.8Low133 Ų13391.6 Ų91.670%0.69647%0.472SS*.Hα-helixtrans-61.3-32.2176.8-166.273000112.5E526 V527L523-E526 WeakPolarHBondContact O-CB 3.47Å; L523-E526 PolarHBondContact O-N 2.67Å; L523-V527 WeakPolarHBondContact O-CG2 3.34Å; L523-V527 PolarHBondContact O-N 3.12Å
524Q74.7Confident68.8Low125 Ų12595.1 Ų95.158%0.58449%0.488SS*.Hα-helixtrans-67.3-44.2176.6-170.963.140.300111.3S522 E526 V527 D528S522-Q524 PolarHBondContact O-N 3.4Å; Q524-E526 VanDerWaalsContact C-N 3.3Å; Q524-E526 PolarHBondContact O-N 2.79Å; Q524-V527 PolarHBondContact O-N 3.46Å; Q524-D528 PolarHBondContact O-N 3.11Å
525Q76.3Confident69.8Low76 Ų7697.3 Ų97.336%0.35549%0.493SS..Hα-helixtrans-62.6-39.2175.1-169.7-171.122.600111.2S521 S522 D528 I529S521-Q525 PolarHBondContact OG-OE1 2.97Å; S522-Q525 PolarHBondContact O-N 3.16Å; S522-Q525 WeakPolarHBondContact OG-CB 3.3Å; S522-Q525 PolarHBondContact OG-N 3.46Å; Q525-D528 PolarHBondContact O-N 2.74Å; Q525-I529 HydrophobicContact CG-CD1 3.74Å; Q525-I529 HydrophobicContact CG-CG1 4.42Å; Q525-I529 VanDerWaalsContact O-CB 3.25Å; Q525-I529 WeakPolarHBondContact O-CB 3.26Å; Q525-I529 WeakPolarHBondContact O-CG1 3.3Å; Q525-I529 PolarHBondContact O-N 3.23Å
526E76.3Confident70.6Confident51 Ų5198.7 Ų98.724%0.23850%0.498CS..Hα-helixtrans-59.6-46172.9-177.2175.4176.400112.3Y520 S522 L523 Q524 K530Y520-E526 VanDerWaalsContact CD1-CA 3.43Å; Y520-E526 HydrophobicContact CD1-CB 3.71Å; Y520-E526 HydrophobicContact CD1-CG 4.01Å; Y520-E526 HydrophobicContact CD2-CB 3.93Å; Y520-E526 HydrophobicContact CD2-CG 3.63Å; Y520-E526 HydrophobicContact CE1-CB 4.22Å; Y520-E526 HydrophobicContact CE1-CG 4.09Å; Y520-E526 HydrophobicContact CE2-CB 4.45Å; Y520-E526 HydrophobicContact CE2-CG 3.76Å; Y520-E526 HydrophobicContact CG-CB 3.53Å; Y520-E526 HydrophobicContact CG-CG 3.77Å; S522-E526 PolarHBondContact O-N 2.86Å; L523-E526 WeakPolarHBondContact O-CB 3.47Å; L523-E526 PolarHBondContact O-N 2.67Å; Q524-E526 VanDerWaalsContact C-N 3.3Å; Q524-E526 PolarHBondContact O-N 2.79Å; E526-K530 HydrophobicContact CG-CD 3.89Å; E526-K530 HydrophobicContact CG-CG 4.42Å; E526-K530 VanDerWaalsContact O-CB 3.22Å; E526-K530 WeakPolarHBondContact O-CB 3.2Å; E526-K530 VanDerWaalsContact O-CG 3.29Å; E526-K530 WeakPolarHBondContact O-CG 3.13Å; E526-K530 PolarHBondContact O-N 3.1Å; E526-K530 WeakPolarHBondContact OE1-CE 3.37Å; E526-K530 IonicContact OE1-NZ 3.45Å; E526-K530 PolarHBondContact OE1-NZ 3.47Å
527V78Confident71.8Confident72 Ų7295.9 Ų95.944%0.43648%0.483SS..Hα-helixtrans-63.9-46.5177.6169.50000111.6L523 Q524 I529 K530 T531L523-V527 WeakPolarHBondContact O-CG2 3.34Å; L523-V527 PolarHBondContact O-N 3.12Å; Q524-V527 PolarHBondContact O-N 3.46Å; V527-I529 PolarHBondContact O-N 3.48Å; V527-K530 PolarHBondContact O-N 3.09Å; V527-T531 VanDerWaalsContact O-CB 3.22Å; V527-T531 WeakPolarHBondContact O-CB 3.46Å; V527-T531 PolarHBondContact O-N 3.16Å; V527-T531 PolarHBondContact O-OG1 3.1Å
528D77.3Confident73Confident81 Ų8193.6 Ų93.643%0.43347%0.474SS..Hα-helixtrans-64.1-40.8-179.3-73.3-22.4000112.1Q524 Q525 T531 K532Q524-D528 PolarHBondContact O-N 3.11Å; Q525-D528 PolarHBondContact O-N 2.74Å; D528-T531 PolarHBondContact O-N 3.26Å; D528-K532 WeakPolarHBondContact O-CG 3.4Å; D528-K532 PolarHBondContact O-N 3.11Å
529I73.7Confident73.8Confident28 Ų2893.7 Ų93.714%0.14448%0.48CS..Hα-helixtrans-71.3-47.2178.1-71.1176.9000111.1E518 Y520 Q525 V527 T531 K532 K533E518-I529 WeakPolarHBondContact OE1-CG2 3.19Å; E518-I529 WeakPolarHBondContact OE2-CG2 3.45Å; Y520-I529 HydrophobicContact CD1-CD1 4.33Å; Y520-I529 HydrophobicContact CE1-CB 4.23Å; Y520-I529 HydrophobicContact CE1-CD1 4.4Å; Y520-I529 HydrophobicContact CE1-CG2 3.99Å; Q525-I529 HydrophobicContact CG-CD1 3.74Å; Q525-I529 HydrophobicContact CG-CG1 4.42Å; Q525-I529 VanDerWaalsContact O-CB 3.25Å; Q525-I529 WeakPolarHBondContact O-CB 3.26Å; Q525-I529 WeakPolarHBondContact O-CG1 3.3Å; Q525-I529 PolarHBondContact O-N 3.23Å; V527-I529 PolarHBondContact O-N 3.48Å; I529-T531 PolarHBondContact O-N 3.47Å; I529-K532 CarbonylContact O-C 3.59Å; I529-K532 WeakPolarHBondContact O-CA 3.2Å; I529-K532 WeakPolarHBondContact O-CB 3.31Å; I529-K532 PolarHBondContact O-N 3.19Å; I529-K533 PolarHBondContact O-N 3.05Å
530K76.6Confident74.2Confident104 Ų10491.5 Ų91.545%0.45246%0.458SS..Hα-helixtrans-59.6-34.3173.5-76.2-179.5175176.90111.7E526 V527 K533 L534E526-K530 HydrophobicContact CG-CD 3.89Å; E526-K530 HydrophobicContact CG-CG 4.42Å; E526-K530 VanDerWaalsContact O-CB 3.22Å; E526-K530 WeakPolarHBondContact O-CB 3.2Å; E526-K530 VanDerWaalsContact O-CG 3.29Å; E526-K530 WeakPolarHBondContact O-CG 3.13Å; E526-K530 PolarHBondContact O-N 3.1Å; E526-K530 WeakPolarHBondContact OE1-CE 3.37Å; E526-K530 IonicContact OE1-NZ 3.45Å; E526-K530 PolarHBondContact OE1-NZ 3.47Å; V527-K530 PolarHBondContact O-N 3.09Å; K530-K533 PolarHBondContact O-N 3.41Å; K530-L534 VanDerWaalsContact O-CB 3.22Å; K530-L534 WeakPolarHBondContact O-CB 3.25Å; K530-L534 PolarHBondContact O-N 3.13Å
531T81.4Confident74.6Confident59 Ų5992.2 Ų92.236%0.36247%0.467SS..Hα-helixtrans-66.8-40.3173.4-600000111.8V527 D528 I529 K535V527-T531 VanDerWaalsContact O-CB 3.22Å; V527-T531 WeakPolarHBondContact O-CB 3.46Å; V527-T531 PolarHBondContact O-N 3.16Å; V527-T531 PolarHBondContact O-OG1 3.1Å; D528-T531 PolarHBondContact O-N 3.26Å; I529-T531 PolarHBondContact O-N 3.47Å; T531-K535 WeakPolarHBondContact O-CB 3.22Å; T531-K535 WeakPolarHBondContact O-CG 3.46Å; T531-K535 PolarHBondContact O-N 3Å
532K77.4Confident75Confident143 Ų14392.4 Ų92.462%0.62246%0.456SS*.Hα-helixtrans-66-42.8172.7-73.5170.7-178.4173.80112D528 I529 K535 K536D528-K532 WeakPolarHBondContact O-CG 3.4Å; D528-K532 PolarHBondContact O-N 3.11Å; I529-K532 CarbonylContact O-C 3.59Å; I529-K532 WeakPolarHBondContact O-CA 3.2Å; I529-K532 WeakPolarHBondContact O-CB 3.31Å; I529-K532 PolarHBondContact O-N 3.19Å; K532-K535 PolarHBondContact O-N 2.75Å; K532-K536 PolarHBondContact O-N 2.97Å
533K70.6Confident74.8Confident45 Ų4592.2 Ų92.220%0.19646%0.458CS..Hα-helixtrans-61.3-47173.8-78.4-178.1164.5171.50111.5L514 E515 E518 I529 K530 K535 K536 L537L514-K533 VanDerWaalsContact O-CE 3.24Å; L514-K533 WeakPolarHBondContact O-CE 3.22Å; L514-K533 PolarHBondContact O-NZ 3.28Å; E515-K533 PolarHBondContact O-NZ 3.43Å; E518-K533 WeakPolarHBondContact OE2-CE 3.29Å; E518-K533 IonicContact OE2-NZ 3.23Å; E518-K533 PolarHBondContact OE2-NZ 3.11Å; I529-K533 PolarHBondContact O-N 3.05Å; K530-K533 PolarHBondContact O-N 3.41Å; K533-K535 VanDerWaalsContact C-N 3.33Å; K533-K535 PolarHBondContact O-N 2.87Å; K533-K536 PolarHBondContact O-N 3.27Å; K533-L537 WeakPolarHBondContact O-CB 3.5Å; K533-L537 WeakPolarHBondContact O-CG 3.38Å; K533-L537 PolarHBondContact O-N 3.35Å
534L75.5Confident74.6Confident122 Ų12289.4 Ų89.464%0.63945%0.446SS*.Hα-helixtrans-59.6-42175.5-174.265.9000111.4K530 F538K530-L534 VanDerWaalsContact O-CB 3.22Å; K530-L534 WeakPolarHBondContact O-CB 3.25Å; K530-L534 PolarHBondContact O-N 3.13Å; L534-F538 WeakPolarHBondContact O-CB 3.46Å; L534-F538 PolarHBondContact O-N 3.06Å
535K75.7Confident74.6Confident143 Ų14389.9 Ų89.962%0.62245%0.446SS*.Hα-helixtrans-61.8-47.6173-76.7176.6179.2-177.80112.3T531 K532 K533 F538 S539T531-K535 WeakPolarHBondContact O-CB 3.22Å; T531-K535 WeakPolarHBondContact O-CG 3.46Å; T531-K535 PolarHBondContact O-N 3Å; K532-K535 PolarHBondContact O-N 2.75Å; K533-K535 VanDerWaalsContact C-N 3.33Å; K533-K535 PolarHBondContact O-N 2.87Å; K535-F538 PolarHBondContact O-N 3.01Å; K535-S539 PolarHBondContact O-N 2.65Å; K535-S539 PolarHBondContact O-OG 3.03Å
536K71.7Confident74.4Confident132 Ų13288.4 Ų88.457%0.57445%0.446SS*.Hα-helixtrans-59.4-48.5176.1-79.3-169.1174-167.90112.2K532 K533 F538 S539 K540K532-K536 PolarHBondContact O-N 2.97Å; K533-K536 PolarHBondContact O-N 3.27Å; K536-F538 VanDerWaalsContact C-N 3.35Å; K536-S539 PolarHBondContact O-N 2.89Å; K536-K540 PolarHBondContact O-N 3.23Å
537L73.7Confident74.2Confident95 Ų9589.8 Ų89.850%0.49745%0.453SS..Hα-helixtrans-65.6-37.3178.6-71.5172.5000111.9K533 K540 L541K533-L537 WeakPolarHBondContact O-CB 3.5Å; K533-L537 WeakPolarHBondContact O-CG 3.38Å; K533-L537 PolarHBondContact O-N 3.35Å; L537-K540 PolarHBondContact O-N 2.92Å; L537-L541 VanDerWaalsContact O-CB 3.24Å; L537-L541 WeakPolarHBondContact O-CB 3.33Å; L537-L541 PolarHBondContact O-N 3.15Å
538F75.8Confident74Confident124 Ų12490.4 Ų90.454%0.54445%0.453SS..Hα-helixtrans-64.7-41.9173.3-174.7-92.7000111.3L534 K535 K536 L541 Q542L534-F538 WeakPolarHBondContact O-CB 3.46Å; L534-F538 PolarHBondContact O-N 3.06Å; K535-F538 PolarHBondContact O-N 3.01Å; K536-F538 VanDerWaalsContact C-N 3.35Å; F538-L541 PolarHBondContact O-N 3.17Å; F538-Q542 WeakPolarHBondContact O-CB 3.22Å; F538-Q542 PolarHBondContact O-N 2.95Å
539S71.9Confident74Confident53 Ų5391.3 Ų91.337%0.37145%0.454SS..Hα-helixtrans-64.5-42.8173-63.20000112.7K535 K536 Q542 A543K535-S539 PolarHBondContact O-N 2.65Å; K535-S539 PolarHBondContact O-OG 3.03Å; K536-S539 PolarHBondContact O-N 2.89Å; S539-Q542 PolarHBondContact O-N 3.23Å; S539-A543 WeakPolarHBondContact O-CB 3.44Å; S539-A543 PolarHBondContact O-N 3.03Å
540K70.1Confident73.9Confident96 Ų9691.4 Ų91.442%0.41746%0.455SS..Hα-helixtrans-60-46.7172.7-75.3-173.1175.8-176.40110.9E511 K536 L537 Q542 A543 V544E511-K540 IonicContact OE1-NZ 3.6Å; E511-K540 IonicContact OE2-NZ 3.11Å; E511-K540 PolarHBondContact OE2-NZ 2.99Å; K536-K540 PolarHBondContact O-N 3.23Å; L537-K540 PolarHBondContact O-N 2.92Å; K540-Q542 PolarHBondContact O-N 3.45Å; K540-A543 PolarHBondContact O-N 3.21Å; K540-V544 WeakPolarHBondContact O-CG2 3.42Å; K540-V544 PolarHBondContact O-N 3.32Å
541L74.6Confident73.6Confident90 Ų9089.2 Ų89.247%0.47145%0.448SS..Hα-helixtrans-62.8-39.9176.718065.6000112.4L537 F538 V544 K545L537-L541 VanDerWaalsContact O-CB 3.24Å; L537-L541 WeakPolarHBondContact O-CB 3.33Å; L537-L541 PolarHBondContact O-N 3.15Å; F538-L541 PolarHBondContact O-N 3.17Å; L541-V544 PolarHBondContact O-N 3.47Å; L541-K545 HydrophobicContact CG-CD 4.41Å; L541-K545 WeakPolarHBondContact O-CB 3.41Å; L541-K545 VanDerWaalsContact O-CG 3.32Å; L541-K545 WeakPolarHBondContact O-CG 3.22Å; L541-K545 PolarHBondContact O-N 2.85Å
542Q75.9Confident73.3Confident113 Ų11391.8 Ų91.853%0.52846%0.456SS..Hα-helixtrans-69.6-37.5178.5-171.51714.300111.4F538 S539 K540 K545 A546F538-Q542 WeakPolarHBondContact O-CB 3.22Å; F538-Q542 PolarHBondContact O-N 2.95Å; S539-Q542 PolarHBondContact O-N 3.23Å; K540-Q542 PolarHBondContact O-N 3.45Å; Q542-K545 PolarHBondContact O-N 2.98Å; Q542-A546 WeakPolarHBondContact O-CB 3.1Å; Q542-A546 PolarHBondContact O-N 3.4Å
543A69.9Low73.3Confident52 Ų5290.1 Ų90.143%0.4345%0.45SS..Hα-helixtrans-63.4-46.6171.900000111.8S539 K540 K545 A546 E547S539-A543 WeakPolarHBondContact O-CB 3.44Å; S539-A543 PolarHBondContact O-N 3.03Å; K540-A543 PolarHBondContact O-N 3.21Å; A543-K545 PolarHBondContact O-N 3Å; A543-A546 PolarHBondContact O-N 3.49Å; A543-E547 PolarHBondContact O-N 3.28Å
544V70.6Confident73.3Confident73 Ų7389.1 Ų89.144%0.44245%0.447SS..Hα-helixtrans-64.8-38.8176.1172.80000111.7K540 L541 E547 I548K540-V544 WeakPolarHBondContact O-CG2 3.42Å; K540-V544 PolarHBondContact O-N 3.32Å; L541-V544 PolarHBondContact O-N 3.47Å; V544-E547 PolarHBondContact O-N 2.84Å; V544-I548 HydrophobicContact CG1-CD1 3.98Å; V544-I548 VanDerWaalsContact O-CG1 3.31Å; V544-I548 WeakPolarHBondContact O-CG1 3.24Å; V544-I548 PolarHBondContact O-N 3.49Å
545K74.1Confident73.1Confident136 Ų13689.4 Ų89.459%0.59144%0.444SS*.Hα-helixtrans-64.2-40.8173.7-79.3-176.6175.5-168.10112.4L541 Q542 A543 I548 H549L541-K545 HydrophobicContact CG-CD 4.41Å; L541-K545 WeakPolarHBondContact O-CB 3.41Å; L541-K545 VanDerWaalsContact O-CG 3.32Å; L541-K545 WeakPolarHBondContact O-CG 3.22Å; L541-K545 PolarHBondContact O-N 2.85Å; Q542-K545 PolarHBondContact O-N 2.98Å; A543-K545 PolarHBondContact O-N 3Å; K545-I548 PolarHBondContact O-N 2.68Å; K545-H549 WeakPolarHBondContact O-CB 3.32Å; K545-H549 PolarHBondContact O-N 3.43Å
546A72.5Confident73.2Confident44 Ų4487 Ų8736%0.36444%0.437SS..Hα-helixtrans-65-39.7173.800000111.3Q542 A543 H549 D550Q542-A546 WeakPolarHBondContact O-CB 3.1Å; Q542-A546 PolarHBondContact O-N 3.4Å; A543-A546 PolarHBondContact O-N 3.49Å; A546-H549 PolarHBondContact O-N 3.05Å; A546-D550 VanDerWaalsContact O-CB 3.32Å; A546-D550 WeakPolarHBondContact O-CB 3.4Å; A546-D550 PolarHBondContact O-N 2.83Å
547E71.4Confident73.4Confident80 Ų8085.9 Ų85.937%0.37443%0.432SS..Hα-helixtrans-64.1-41.9174.5-174.5174.5-160.600112.3A543 V544 H549 D550 L551A543-E547 PolarHBondContact O-N 3.28Å; V544-E547 PolarHBondContact O-N 2.84Å; E547-H549 VanDerWaalsContact C-N 3.35Å; E547-D550 PolarHBondContact O-N 3.46Å; E547-L551 HydrophobicContact CG-CD1 4.06Å; E547-L551 WeakPolarHBondContact O-CB 3.36Å; E547-L551 WeakPolarHBondContact O-CD1 3.18Å; E547-L551 WeakPolarHBondContact O-CG 3.31Å; E547-L551 PolarHBondContact O-N 2.98Å
548I74.1Confident73.1Confident86 Ų8685.2 Ų85.244%0.44143%0.427SS..Hα-helixtrans-62.2-43.4174.2-69.4165.2000110.8V544 K545 L551 Q552V544-I548 HydrophobicContact CG1-CD1 3.98Å; V544-I548 VanDerWaalsContact O-CG1 3.31Å; V544-I548 WeakPolarHBondContact O-CG1 3.24Å; V544-I548 PolarHBondContact O-N 3.49Å; K545-I548 PolarHBondContact O-N 2.68Å; I548-L551 PolarHBondContact O-N 2.93Å; I548-Q552 WeakPolarHBondContact O-CB 3.34Å; I548-Q552 VanDerWaalsContact O-CG 3.3Å; I548-Q552 WeakPolarHBondContact O-CG 3.48Å; I548-Q552 PolarHBondContact O-N 2.79Å
549H76.4Confident73.1Confident100 Ų10086.9 Ų86.946%0.46343%0.429SS..Hα-helixtrans-63.8-49.8177.2-173-83.6000111.8K545 A546 E547 L551 Q552 E553K545-H549 WeakPolarHBondContact O-CB 3.32Å; K545-H549 PolarHBondContact O-N 3.43Å; A546-H549 PolarHBondContact O-N 3.05Å; E547-H549 VanDerWaalsContact C-N 3.35Å; H549-L551 VanDerWaalsContact C-N 3.26Å; H549-L551 PolarHBondContact O-N 3.16Å; H549-Q552 WeakPolarHBondContact O-CB 3.27Å; H549-Q552 PolarHBondContact O-N 2.85Å; H549-Q552 VanDerWaalsContact O-N 3.08Å; H549-E553 IonicContact CE1-OE1 2.73Å; H549-E553 PolarHBondContact CE1-OE1 3.2Å; H549-E553 VanDerWaalsContact CE1-OE1 3.23Å; H549-E553 IonicContact CE1-OE2 3.94Å; H549-E553 IonicContact ND1-OE1 3.17Å; H549-E553 IonicContact ND1-OE2 4Å; H549-E553 PolarHBondContact O-N 3.35Å
550D72.9Confident73.3Confident30 Ų3089.4 Ų89.416%0.1644%0.435CS..Hα-helixtrans-52.9-43.1173.9-84.316.7000112K55 R332 A546 E547 E554K55-D550 WeakPolarHBondContact CE-OD2 2.81Å; K55-D550 IonicContact NZ-OD1 3.77Å; K55-D550 IonicContact NZ-OD2 3.2Å; K55-D550 PolarHBondContact NZ-OD2 3.24Å; R332-D550 IonicContact CZ-OD2 2.79Å; R332-D550 IonicContact NH2-OD2 3.83Å; R332-D550 PolarHBondContact NH2-OD2 2.85Å; A546-D550 VanDerWaalsContact O-CB 3.32Å; A546-D550 WeakPolarHBondContact O-CB 3.4Å; A546-D550 PolarHBondContact O-N 2.83Å; E547-D550 PolarHBondContact O-N 3.46Å; D550-E554 VanDerWaalsContact O-CB 3.29Å; D550-E554 WeakPolarHBondContact O-CB 3.29Å; D550-E554 PolarHBondContact O-N 3.41Å
551L69.1Low73.3Confident58 Ų5888.1 Ų88.130%0.30443%0.431SS..Hα-helixtrans-70.3-35.8178.6-73.9169000111.9R336 E547 I548 H549 H555R336-L551 VanDerWaalsContact NH2-CD2 3.32Å; E547-L551 HydrophobicContact CG-CD1 4.06Å; E547-L551 WeakPolarHBondContact O-CB 3.36Å; E547-L551 WeakPolarHBondContact O-CD1 3.18Å; E547-L551 WeakPolarHBondContact O-CG 3.31Å; E547-L551 PolarHBondContact O-N 2.98Å; I548-L551 PolarHBondContact O-N 2.93Å; H549-L551 VanDerWaalsContact C-N 3.26Å; H549-L551 PolarHBondContact O-N 3.16Å; L551-H555 WeakPolarHBondContact O-CB 3.41Å; L551-H555 PolarHBondContact O-N 2.89Å
552Q74.7Confident73Confident113 Ų11389.7 Ų89.753%0.52844%0.439SS..Hα-helixtrans-67.7-44.7173.7-75.7174-3000111.3I548 H549 H555 I556I548-Q552 WeakPolarHBondContact O-CB 3.34Å; I548-Q552 VanDerWaalsContact O-CG 3.3Å; I548-Q552 WeakPolarHBondContact O-CG 3.48Å; I548-Q552 PolarHBondContact O-N 2.79Å; H549-Q552 WeakPolarHBondContact O-CB 3.27Å; H549-Q552 PolarHBondContact O-N 2.85Å; H549-Q552 VanDerWaalsContact O-N 3.08Å; Q552-H555 PolarHBondContact O-N 2.79Å; Q552-I556 WeakPolarHBondContact O-CB 3.48Å; Q552-I556 WeakPolarHBondContact O-CD1 3.39Å; Q552-I556 WeakPolarHBondContact O-CG1 3.17Å; Q552-I556 PolarHBondContact O-N 2.9Å
553E77.5Confident73.1Confident108 Ų10888.8 Ų88.851%0.50544%0.435SS..Hα-helixtrans-62.7-44.3174.1-73.6-172.2141.900112.1H549 H555 I556 K557H549-E553 IonicContact CE1-OE1 2.73Å; H549-E553 PolarHBondContact CE1-OE1 3.2Å; H549-E553 VanDerWaalsContact CE1-OE1 3.23Å; H549-E553 IonicContact CE1-OE2 3.94Å; H549-E553 IonicContact ND1-OE1 3.17Å; H549-E553 IonicContact ND1-OE2 4Å; H549-E553 PolarHBondContact O-N 3.35Å; E553-H555 VanDerWaalsContact C-N 3.34Å; E553-H555 PolarHBondContact O-N 2.81Å; E553-I556 PolarHBondContact O-N 3.41Å; E553-K557 VanDerWaalsContact O-CB 3.28Å; E553-K557 WeakPolarHBondContact O-CB 3.43Å; E553-K557 PolarHBondContact O-N 2.82Å
554E71.3Confident73.4Confident24 Ų2492.6 Ų92.611%0.11244%0.444CS..Hα-helixtrans-61.4-43176.4-177158.5-132.700111R251 R332 D550 K557 E558R251-E554 IonicContact NH2-OE1 3.86Å; R251-E554 PolarHBondContact NH2-OE1 3.35Å; R332-E554 IonicContact CZ-OE2 2.91Å; R332-E554 IonicContact NH1-OE1 2.8Å; R332-E554 IonicContact NH1-OE2 2.68Å; R332-E554 PolarHBondContact NH1-OE2 2.87Å; D550-E554 VanDerWaalsContact O-CB 3.29Å; D550-E554 WeakPolarHBondContact O-CB 3.29Å; D550-E554 PolarHBondContact O-N 3.41Å; E554-K557 PolarHBondContact O-N 2.88Å; E554-E558 WeakPolarHBondContact CG-OE1 3.47Å; E554-E558 WeakPolarHBondContact O-CB 3.47Å; E554-E558 WeakPolarHBondContact O-CG 3.43Å; E554-E558 PolarHBondContact O-N 3.27Å
555H71.8Confident73.3Confident127 Ų12791.7 Ų91.759%0.58844%0.439SS*.Hα-helixtrans-69.1-37.5176.8-176.3-94.1000113.5L551 Q552 E553 R559L551-H555 WeakPolarHBondContact O-CB 3.41Å; L551-H555 PolarHBondContact O-N 2.89Å; Q552-H555 PolarHBondContact O-N 2.79Å; E553-H555 VanDerWaalsContact C-N 3.34Å; E553-H555 PolarHBondContact O-N 2.81Å; H555-R559 VanDerWaalsContact O-CB 3.29Å; H555-R559 WeakPolarHBondContact O-CB 3.28Å; H555-R559 PolarHBondContact O-N 3.47Å
556I77.6Confident73.4Confident93 Ų9391.1 Ų91.148%0.47744%0.438SS..Hα-helixtrans-63.3-45.6172.9-72.4162.5000109.7Q552 E553 R559 Q560Q552-I556 WeakPolarHBondContact O-CB 3.48Å; Q552-I556 WeakPolarHBondContact O-CD1 3.39Å; Q552-I556 WeakPolarHBondContact O-CG1 3.17Å; Q552-I556 PolarHBondContact O-N 2.9Å; E553-I556 PolarHBondContact O-N 3.41Å; I556-R559 WeakPolarHBondContact O-CB 3.37Å; I556-R559 PolarHBondContact O-N 2.9Å; I556-Q560 WeakPolarHBondContact O-CG 3.32Å; I556-Q560 PolarHBondContact O-N 3.49Å
557K74.9Confident73.8Confident108 Ų10893.5 Ų93.547%0.4745%0.445SS..Hα-helixtrans-65.3-43.6179.1-173.7178.2-179.5-177.20112.2E553 E554 R559 Q560 E561E553-K557 VanDerWaalsContact O-CB 3.28Å; E553-K557 WeakPolarHBondContact O-CB 3.43Å; E553-K557 PolarHBondContact O-N 2.82Å; E554-K557 PolarHBondContact O-N 2.88Å; K557-R559 VanDerWaalsContact C-N 3.33Å; K557-R559 PolarHBondContact O-N 2.9Å; K557-Q560 PolarHBondContact O-N 2.86Å; K557-E561 WeakPolarHBondContact CE-OE1 3.28Å; K557-E561 WeakPolarHBondContact O-CB 3.32Å; K557-E561 WeakPolarHBondContact O-CG 3.32Å; K557-E561 PolarHBondContact O-N 3.39Å
558E67.8Low74Confident81 Ų8195.8 Ų95.838%0.37946%0.455SS..Hα-helixtrans-61.7-40.9174.1-77.7171.4-172.100111.6R251 E554 E561 L562R251-E558 IonicContact NH2-OE1 3.86Å; R251-E558 PolarHBondContact NH2-OE1 3.47Å; R251-E558 VanDerWaalsContact NH2-OE1 3.15Å; E554-E558 WeakPolarHBondContact CG-OE1 3.47Å; E554-E558 WeakPolarHBondContact O-CB 3.47Å; E554-E558 WeakPolarHBondContact O-CG 3.43Å; E554-E558 PolarHBondContact O-N 3.27Å; E558-E561 PolarHBondContact O-N 2.98Å; E558-L562 WeakPolarHBondContact O-CB 3.37Å; E558-L562 VanDerWaalsContact O-CG 3.27Å; E558-L562 WeakPolarHBondContact O-CG 3.42Å; E558-L562 PolarHBondContact O-N 3.34Å
559R76Confident74Confident160 Ų16096.5 Ų96.560%0.60446%0.459SS*.Hα-helixtrans-61.5-43.3173.4180177.3169.9178.9-3.1112H555 I556 K557 L562 E563H555-R559 VanDerWaalsContact O-CB 3.29Å; H555-R559 WeakPolarHBondContact O-CB 3.28Å; H555-R559 PolarHBondContact O-N 3.47Å; I556-R559 WeakPolarHBondContact O-CB 3.37Å; I556-R559 PolarHBondContact O-N 2.9Å; K557-R559 VanDerWaalsContact C-N 3.33Å; K557-R559 PolarHBondContact O-N 2.9Å; R559-L562 PolarHBondContact O-N 3.31Å; R559-E563 VanDerWaalsContact O-CB 3.28Å; R559-E563 WeakPolarHBondContact O-CB 3.3Å; R559-E563 PolarHBondContact O-N 3.48Å
560Q77Confident74.3Confident106 Ų10694.4 Ų94.450%0.49545%0.453SS..Hα-helixtrans-65-42.8175.7-73.5172.7-19.100112.3I556 K557 L562 E563 Q564I556-Q560 WeakPolarHBondContact O-CG 3.32Å; I556-Q560 PolarHBondContact O-N 3.49Å; K557-Q560 PolarHBondContact O-N 2.86Å; Q560-L562 VanDerWaalsContact C-N 3.33Å; Q560-L562 PolarHBondContact O-N 2.94Å; Q560-E563 PolarHBondContact O-N 3.26Å; Q560-Q564 WeakPolarHBondContact O-CB 3.45Å; Q560-Q564 WeakPolarHBondContact O-CG 3.48Å; Q560-Q564 PolarHBondContact O-N 3.44Å
561E69.5Low74.7Confident68 Ų6899.8 Ų99.832%0.31847%0.472SS..Hα-helixtrans-60.9-41175-73.9173.8-169.100111R251 K557 E558 T565R251-E561 IonicContact NH1-OE1 2.62Å; R251-E561 PolarHBondContact NH1-OE1 3.32Å; R251-E561 VanDerWaalsContact NH1-OE1 3.17Å; R251-E561 IonicContact NH1-OE2 3.83Å; R251-E561 PolarHBondContact NH1-OE2 2.82Å; R251-E561 VanDerWaalsContact NH1-OE2 3.11Å; K557-E561 WeakPolarHBondContact CE-OE1 3.28Å; K557-E561 WeakPolarHBondContact O-CB 3.32Å; K557-E561 WeakPolarHBondContact O-CG 3.32Å; K557-E561 PolarHBondContact O-N 3.39Å; E558-E561 PolarHBondContact O-N 2.98Å; E561-T565 WeakPolarHBondContact O-CB 3.21Å; E561-T565 PolarHBondContact O-N 2.94Å; E561-T565 PolarHBondContact O-OG1 3.49Å
562L68.1Low75.2Confident123 Ų123100.1 Ų100.164%0.64447%0.472SS*.Hα-helixtrans-67.5-42174.5-72.8170.7000112.8E558 R559 Q560 T565 Q566E558-L562 WeakPolarHBondContact O-CB 3.37Å; E558-L562 VanDerWaalsContact O-CG 3.27Å; E558-L562 WeakPolarHBondContact O-CG 3.42Å; E558-L562 PolarHBondContact O-N 3.34Å; R559-L562 PolarHBondContact O-N 3.31Å; Q560-L562 VanDerWaalsContact C-N 3.33Å; Q560-L562 PolarHBondContact O-N 2.94Å; L562-T565 WeakPolarHBondContact O-CB 3.29Å; L562-T565 PolarHBondContact O-N 3.19Å; L562-Q566 WeakPolarHBondContact O-CB 3.32Å; L562-Q566 PolarHBondContact O-N 3.13Å
563E77.8Confident75.4Confident95 Ų9599.3 Ų99.344%0.44447%0.471SS..Hα-helixtrans-67-41179.2-175.3162.5-162.500111.7R559 Q560 Q566 N567R559-E563 VanDerWaalsContact O-CB 3.28Å; R559-E563 WeakPolarHBondContact O-CB 3.3Å; R559-E563 PolarHBondContact O-N 3.48Å; Q560-E563 PolarHBondContact O-N 3.26Å; E563-Q566 PolarHBondContact O-N 3.33Å; E563-N567 WeakPolarHBondContact O-CB 3.28Å; E563-N567 VanDerWaalsContact O-CG 3.24Å; E563-N567 PolarHBondContact O-N 3.4Å; E563-N567 PolarHBondContact O-ND2 2.92Å
564Q76.2Confident75.9Confident131 Ų131100.9 Ų100.961%0.61248%0.476SS*.Hα-helixtrans-59.5-47.1169.5-74177.1-0.800111.5Q560 Q566 N567 E568Q560-Q564 WeakPolarHBondContact O-CB 3.45Å; Q560-Q564 WeakPolarHBondContact O-CG 3.48Å; Q560-Q564 PolarHBondContact O-N 3.44Å; Q564-Q566 VanDerWaalsContact C-N 3.32Å; Q564-Q566 PolarHBondContact O-N 3.22Å; Q564-N567 PolarHBondContact O-N 3.3Å; Q564-E568 WeakPolarHBondContact O-CG 3.39Å; Q564-E568 PolarHBondContact O-N 2.9Å
565T68.1Low76.6Confident55 Ų55104.5 Ų104.534%0.33750%0.495SS..Hα-helixtrans-60.5-41.4177.1-54.20000111.5E561 L562 E568 L569E561-T565 WeakPolarHBondContact O-CB 3.21Å; E561-T565 PolarHBondContact O-N 2.94Å; E561-T565 PolarHBondContact O-OG1 3.49Å; L562-T565 WeakPolarHBondContact O-CB 3.29Å; L562-T565 PolarHBondContact O-N 3.19Å; T565-E568 PolarHBondContact O-N 3.2Å; T565-L569 HydrophobicContact CG2-CD1 4.09Å; T565-L569 WeakPolarHBondContact O-CB 3.44Å; T565-L569 VanDerWaalsContact O-CG 3.28Å; T565-L569 WeakPolarHBondContact O-CG 3.19Å; T565-L569 PolarHBondContact O-N 2.81Å
566Q77Confident77.1Confident124 Ų124103.1 Ų103.158%0.57949%0.487SS*.Hα-helixtrans-64-40.7175.9179.5177-18.600112L562 E563 Q564 T570L562-Q566 WeakPolarHBondContact O-CB 3.32Å; L562-Q566 PolarHBondContact O-N 3.13Å; E563-Q566 PolarHBondContact O-N 3.33Å; Q564-Q566 VanDerWaalsContact C-N 3.32Å; Q564-Q566 PolarHBondContact O-N 3.22Å; Q566-T570 WeakPolarHBondContact O-CB 3.41Å; Q566-T570 PolarHBondContact O-N 2.95Å; Q566-T570 PolarHBondContact O-OG1 2.87Å
567N81.1Confident77.5Confident94 Ų94103 Ų10350%0.50349%0.485SS..Hα-helixtrans-67.7-40.9177-72.7-20.2000111.7E563 Q564 T570 R571E563-N567 WeakPolarHBondContact O-CB 3.28Å; E563-N567 VanDerWaalsContact O-CG 3.24Å; E563-N567 PolarHBondContact O-N 3.4Å; E563-N567 PolarHBondContact O-ND2 2.92Å; Q564-N567 PolarHBondContact O-N 3.3Å; N567-T570 PolarHBondContact O-N 3.11Å; N567-R571 WeakPolarHBondContact O-CB 3.48Å; N567-R571 PolarHBondContact O-N 3.38Å
568E75.4Confident78Confident127 Ų127102.7 Ų102.759%0.59349%0.488SS*.Hα-helixtrans-62.2-47.9172.9-73.2-172.8171.400112.3Q564 T565 T570 R571 E572Q564-E568 WeakPolarHBondContact O-CG 3.39Å; Q564-E568 PolarHBondContact O-N 2.9Å; T565-E568 PolarHBondContact O-N 3.2Å; E568-T570 VanDerWaalsContact C-N 3.29Å; E568-T570 PolarHBondContact O-N 3.15Å; E568-R571 WeakPolarHBondContact O-CB 3.42Å; E568-R571 PolarHBondContact O-N 3.47Å; E568-E572 PolarHBondContact O-N 2.86Å
569L73.5Confident78.9Confident102 Ų102102.7 Ų102.753%0.53449%0.489SS..Hα-helixtrans-61.9-38.4176.3-73.4171000111.7T565 E572 L573T565-L569 HydrophobicContact CG2-CD1 4.09Å; T565-L569 WeakPolarHBondContact O-CB 3.44Å; T565-L569 VanDerWaalsContact O-CG 3.28Å; T565-L569 WeakPolarHBondContact O-CG 3.19Å; T565-L569 PolarHBondContact O-N 2.81Å; L569-E572 PolarHBondContact O-N 2.87Å; L569-L573 WeakPolarHBondContact O-CB 3.37Å; L569-L573 PolarHBondContact O-N 3.17Å
570T82.9Confident79.2Confident55 Ų5597.7 Ų97.734%0.33747%0.474SS..Hα-helixtrans-67.6-38.6176.3-62.50000111Q566 N567 E568 L573 K574Q566-T570 WeakPolarHBondContact O-CB 3.41Å; Q566-T570 PolarHBondContact O-N 2.95Å; Q566-T570 PolarHBondContact O-OG1 2.87Å; N567-T570 PolarHBondContact O-N 3.11Å; E568-T570 VanDerWaalsContact C-N 3.29Å; E568-T570 PolarHBondContact O-N 3.15Å; T570-L573 PolarHBondContact O-N 3.47Å; T570-K574 HydrophobicContact CG2-CD 4.32Å; T570-K574 WeakPolarHBondContact O-CB 3.27Å; T570-K574 VanDerWaalsContact O-CG 3.29Å; T570-K574 WeakPolarHBondContact O-CG 3.36Å; T570-K574 PolarHBondContact O-N 3.2Å
571R81.8Confident79.5Confident143 Ų14398.2 Ų98.254%0.5448%0.477SS..Hα-helixtrans-65.7-43.1173.9-170.7179.5-79.3161.8-5.7111.3N567 E568 K574 L575 D687N567-R571 WeakPolarHBondContact O-CB 3.48Å; N567-R571 PolarHBondContact O-N 3.38Å; E568-R571 WeakPolarHBondContact O-CB 3.42Å; E568-R571 PolarHBondContact O-N 3.47Å; R571-K574 PolarHBondContact O-N 3.17Å; R571-L575 WeakPolarHBondContact O-CB 3.5Å; R571-L575 PolarHBondContact O-N 3.33Å; R571-D687 IonicContact NH2-OD1 2.74Å; R571-D687 PolarHBondContact NH2-OD1 3.43Å
572E78.4Confident80.2Confident65 Ų65100.3 Ų100.330%0.30449%0.49SS..Hα-helixtrans-65.1-38.6174.3-160-165.1174.700111.6K263 E568 L569 L575 K576K263-E572 IonicContact NZ-OE1 3.75Å; E568-E572 PolarHBondContact O-N 2.86Å; L569-E572 PolarHBondContact O-N 2.87Å; E572-L575 PolarHBondContact O-N 3.09Å; E572-K576 HydrophobicContact CG-CD 4.49Å; E572-K576 WeakPolarHBondContact O-CG 3.41Å; E572-K576 PolarHBondContact O-N 3.05Å; E572-K576 WeakPolarHBondContact OE1-CE 3.28Å; E572-K576 IonicContact OE1-NZ 3.58Å; E572-K576 PolarHBondContact OE1-NZ 2.6Å; E572-K576 IonicContact OE2-NZ 2.7Å; E572-K576 PolarHBondContact OE2-NZ 2.86Å
573L80.8Confident81.1Confident97 Ų97102.2 Ų102.251%0.50849%0.493SS..Hα-helixtrans-67.4-44.8177-175151.2000111.7L569 T570 L575 K576 H577L569-L573 WeakPolarHBondContact O-CB 3.37Å; L569-L573 PolarHBondContact O-N 3.17Å; T570-L573 PolarHBondContact O-N 3.47Å; L573-L575 VanDerWaalsContact C-N 3.34Å; L573-L575 PolarHBondContact O-N 3.29Å; L573-K576 PolarHBondContact O-N 3.37Å; L573-H577 VanDerWaalsContact CD2-CE1 3.45Å; L573-H577 WeakPolarHBondContact CD2-CE1 3.34Å; L573-H577 WeakPolarHBondContact CD2-ND1 3.46Å; L573-H577 PolarHBondContact O-N 3.42Å; L573-H577 PolarHBondContact O-ND1 3.38Å
574K87.1Confident81.3Confident141 Ų141100.8 Ų100.861%0.61349%0.488SS*.Hα-helixtrans-57.4-45.7172.6-77.6174.6177-179.40111T570 R571 H577 L578T570-K574 HydrophobicContact CG2-CD 4.32Å; T570-K574 WeakPolarHBondContact O-CB 3.27Å; T570-K574 VanDerWaalsContact O-CG 3.29Å; T570-K574 WeakPolarHBondContact O-CG 3.36Å; T570-K574 PolarHBondContact O-N 3.2Å; R571-K574 PolarHBondContact O-N 3.17Å; K574-H577 PolarHBondContact O-N 2.93Å; K574-L578 WeakPolarHBondContact O-CB 3.44Å; K574-L578 PolarHBondContact O-N 2.87Å
575L84.9Confident81.9Confident100 Ų10098.2 Ų98.252%0.52448%0.483SS..Hα-helixtrans-60.5-45.6176.1178.663.3000112.2R571 E572 L573 H577 L578 I579R571-L575 WeakPolarHBondContact O-CB 3.5Å; R571-L575 PolarHBondContact O-N 3.33Å; E572-L575 PolarHBondContact O-N 3.09Å; L573-L575 VanDerWaalsContact C-N 3.34Å; L573-L575 PolarHBondContact O-N 3.29Å; L575-H577 VanDerWaalsContact C-N 3.35Å; L575-H577 PolarHBondContact O-N 2.97Å; L575-L578 PolarHBondContact O-N 3.05Å; L575-I579 HydrophobicContact CD1-CD1 4.24Å; L575-I579 HydrophobicContact CG-CD1 4.08Å; L575-I579 WeakPolarHBondContact O-CG1 3.4Å; L575-I579 PolarHBondContact O-N 3.45Å
576K84.1Confident82.5Confident97 Ų97101 Ų10142%0.42250%0.495SS..Hα-helixtrans-61.4-41.5176.4-74.3166.4-175.4162.20112E572 L573 I579 I580E572-K576 HydrophobicContact CG-CD 4.49Å; E572-K576 WeakPolarHBondContact O-CG 3.41Å; E572-K576 PolarHBondContact O-N 3.05Å; E572-K576 WeakPolarHBondContact OE1-CE 3.28Å; E572-K576 IonicContact OE1-NZ 3.58Å; E572-K576 PolarHBondContact OE1-NZ 2.6Å; E572-K576 IonicContact OE2-NZ 2.7Å; E572-K576 PolarHBondContact OE2-NZ 2.86Å; L573-K576 PolarHBondContact O-N 3.37Å; K576-I579 PolarHBondContact O-N 3.23Å; K576-I580 WeakPolarHBondContact O-CD1 3.5Å; K576-I580 VanDerWaalsContact O-CG1 3.22Å; K576-I580 WeakPolarHBondContact O-CG1 3.49Å; K576-I580 PolarHBondContact O-N 3.05Å
577H84.9Confident82.8Confident92 Ų92100.9 Ų100.943%0.42649%0.494SS..Hα-helixtrans-63.4-45.4175.2-77.773.7000111.7L573 K574 L575 I579 I580 E581L573-H577 VanDerWaalsContact CD2-CE1 3.45Å; L573-H577 WeakPolarHBondContact CD2-CE1 3.34Å; L573-H577 WeakPolarHBondContact CD2-ND1 3.46Å; L573-H577 PolarHBondContact O-N 3.42Å; L573-H577 PolarHBondContact O-ND1 3.38Å; K574-H577 PolarHBondContact O-N 2.93Å; L575-H577 VanDerWaalsContact C-N 3.35Å; L575-H577 PolarHBondContact O-N 2.97Å; H577-I579 VanDerWaalsContact C-N 3.29Å; H577-I579 PolarHBondContact O-N 2.83Å; H577-I580 PolarHBondContact O-N 3.39Å; H577-I580 VanDerWaalsContact O-N 3.13Å; H577-E581 WeakPolarHBondContact O-CB 3.5Å; H577-E581 WeakPolarHBondContact O-CG 3.49Å; H577-E581 PolarHBondContact O-N 2.93Å
578L86.3Confident82.8Confident100 Ų100100.5 Ų100.552%0.52449%0.49SS..Hα-helixtrans-58.8-40.2176.3-166.976.4000112K574 L575 E581 N582K574-L578 WeakPolarHBondContact O-CB 3.44Å; K574-L578 PolarHBondContact O-N 2.87Å; L575-L578 PolarHBondContact O-N 3.05Å; L578-E581 PolarHBondContact O-N 2.89Å; L578-N582 WeakPolarHBondContact O-CB 3.34Å; L578-N582 PolarHBondContact O-N 3.36Å; L578-N582 VanDerWaalsContact O-N 3.07Å; L578-N582 PolarHBondContact O-ND2 3.47Å
579I85.3Confident83.1Confident81 Ų8197.1 Ų97.142%0.41547%0.473SS..Hα-helixtrans-65.1-46.5174.8-67.8164.9000110.8L575 K576 H577 E581 N582 F583L575-I579 HydrophobicContact CD1-CD1 4.24Å; L575-I579 HydrophobicContact CG-CD1 4.08Å; L575-I579 WeakPolarHBondContact O-CG1 3.4Å; L575-I579 PolarHBondContact O-N 3.45Å; K576-I579 PolarHBondContact O-N 3.23Å; H577-I579 VanDerWaalsContact C-N 3.29Å; H577-I579 PolarHBondContact O-N 2.83Å; I579-E581 VanDerWaalsContact C-N 3.29Å; I579-E581 PolarHBondContact O-N 3.08Å; I579-N582 PolarHBondContact O-N 2.97Å; I579-F583 HydrophobicContact CG2-CD2 4.42Å; I579-F583 WeakPolarHBondContact O-CB 3.19Å; I579-F583 PolarHBondContact O-N 2.88Å
580I83.5Confident83.6Confident56 Ų5696.3 Ų96.329%0.28747%0.469SS..Hα-helixtrans-60.1-40.1178.2-69.2162.5000111.1K576 H577 I584 K589K576-I580 WeakPolarHBondContact O-CD1 3.5Å; K576-I580 VanDerWaalsContact O-CG1 3.22Å; K576-I580 WeakPolarHBondContact O-CG1 3.49Å; K576-I580 PolarHBondContact O-N 3.05Å; H577-I580 PolarHBondContact O-N 3.39Å; H577-I580 VanDerWaalsContact O-N 3.13Å; I580-I584 HydrophobicContact CB-CD1 4.31Å; I580-I584 HydrophobicContact CG1-CD1 3.93Å; I580-I584 HydrophobicContact CG2-CD1 4.37Å; I580-I584 WeakPolarHBondContact O-CB 3.33Å; I580-I584 PolarHBondContact O-N 2.83Å; I580-K589 HydrophobicContact CG2-CD 3.78Å; I580-K589 HydrophobicContact CG2-CG 4.24Å
581E83.2Confident83.5Confident117 Ų11798.8 Ų98.855%0.54748%0.475SS..Hα-helixtrans-77.6-32.4-176.4-71.8177.2171.700114H577 L578 I579 K589H577-E581 WeakPolarHBondContact O-CB 3.5Å; H577-E581 WeakPolarHBondContact O-CG 3.49Å; H577-E581 PolarHBondContact O-N 2.93Å; L578-E581 PolarHBondContact O-N 2.89Å; I579-E581 VanDerWaalsContact C-N 3.29Å; I579-E581 PolarHBondContact O-N 3.08Å; E581-K589 IonicContact OE1-NZ 2.89Å
582N84.3Confident83.6Confident111 Ų11195.9 Ų95.959%0.59447%0.469SS*.Hα-helixtrans-95.6-25.2-177.5-69.5-82.4000114.1L578 I579L578-N582 WeakPolarHBondContact O-CB 3.34Å; L578-N582 PolarHBondContact O-N 3.36Å; L578-N582 VanDerWaalsContact O-N 3.07Å; L578-N582 PolarHBondContact O-ND2 3.47Å; I579-N582 PolarHBondContact O-N 2.97Å
583F86.5Confident83.8Confident164 Ų16498 Ų9872%0.71948%0.481SS*.Hα-helixtrans-118.8-12.5-172.3-63.5-90.9000115.1I579I579-F583 HydrophobicContact CG2-CD2 4.42Å; I579-F583 WeakPolarHBondContact O-CB 3.19Å; I579-F583 PolarHBondContact O-N 2.88Å
584I81.8Confident84Confident65 Ų65100 Ų10033%0.33349%0.492SS..SBendtrans-107.3120176.8-53.3-176.7000109.5I580 L586 E588 K589I580-I584 HydrophobicContact CB-CD1 4.31Å; I580-I584 HydrophobicContact CG1-CD1 3.93Å; I580-I584 HydrophobicContact CG2-CD1 4.37Å; I580-I584 WeakPolarHBondContact O-CB 3.33Å; I580-I584 PolarHBondContact O-N 2.83Å; I584-L586 PolarHBondContact O-N 2.95Å; I584-E588 HydrophobicContact CG2-CB 4.34Å; I584-K589 HydrophobicContact CG2-CB 4.42Å
585P89.9Confident83.9Confident76 Ų7696.9 Ų96.949%0.49448%0.476SS..  trans-54.3138.7174.7-2735.4000112.3E587 E588 K589P585-E587 WeakPolarHBondContact CB-OE2 3.4Å; P585-E587 PolarHBondContact O-N 3.38Å; P585-E587 VanDerWaalsContact O-N 3.15Å; P585-E588 PolarHBondContact O-N 2.85Å; P585-K589 PolarHBondContact O-N 3.25Å
586L80.2Confident84.1Confident113 Ų11393.4 Ų93.459%0.59246%0.46SS*.Hα-helixtrans-57.5-32.7-176.3-71.7167.1000112.1I584 N590I584-L586 PolarHBondContact O-N 2.95Å; L586-N590 VanDerWaalsContact O-CB 3.29Å; L586-N590 WeakPolarHBondContact O-CB 3.4Å; L586-N590 PolarHBondContact O-N 3.4Å; L586-N590 PolarHBondContact O-ND2 2.92Å
587E82.3Confident84.3Confident122 Ų12292.2 Ų92.257%0.5746%0.455SS*.Hα-helixtrans-64.5-42.4176.8-5876.5-16900111.9P585 K591P585-E587 WeakPolarHBondContact CB-OE2 3.4Å; P585-E587 PolarHBondContact O-N 3.38Å; P585-E587 VanDerWaalsContact O-N 3.15Å; E587-K591 WeakPolarHBondContact O-CB 3.27Å; E587-K591 WeakPolarHBondContact O-CD 3.35Å; E587-K591 WeakPolarHBondContact O-CG 3.41Å; E587-K591 PolarHBondContact O-N 3.38Å
588E81Confident84.4Confident87 Ų8792 Ų9241%0.40745%0.453SS..Hα-helixtrans-74.7-39.1178.3-63.2-52.7138.200111.4I584 P585 N590 K591 I592I584-E588 HydrophobicContact CG2-CB 4.34Å; P585-E588 PolarHBondContact O-N 2.85Å; E588-N590 VanDerWaalsContact C-N 3.34Å; E588-N590 PolarHBondContact O-N 3.39Å; E588-K591 PolarHBondContact O-N 2.85Å; E588-K591 IonicContact OE1-NZ 2.75Å; E588-K591 PolarHBondContact OE1-NZ 3.47Å; E588-K591 WeakPolarHBondContact OE2-CD 3.33Å; E588-K591 IonicContact OE2-NZ 3.82Å; E588-I592 WeakPolarHBondContact O-CG1 3.33Å; E588-I592 PolarHBondContact O-N 3.06Å
589K81.5Confident84.2Confident55 Ų5588.7 Ų88.724%0.23944%0.436CS..Hα-helixtrans-54.4-50.8170.4-175.5180-178.9176.30110.5I580 E581 I584 P585 I592 M593I580-K589 HydrophobicContact CG2-CD 3.78Å; I580-K589 HydrophobicContact CG2-CG 4.24Å; E581-K589 IonicContact OE1-NZ 2.89Å; I584-K589 HydrophobicContact CG2-CB 4.42Å; P585-K589 PolarHBondContact O-N 3.25Å; K589-I592 PolarHBondContact O-N 2.91Å; K589-M593 VanDerWaalsContact O-CG 3.31Å; K589-M593 WeakPolarHBondContact O-CG 3.42Å; K589-M593 PolarHBondContact O-N 3.32Å
590N84.1Confident83.8Confident85 Ų8593.2 Ų93.246%0.45546%0.455SS..Hα-helixtrans-66.9-37.1-179.9-69.4-19.1000112.8L586 E588 I592 M593 N594L586-N590 VanDerWaalsContact O-CB 3.29Å; L586-N590 WeakPolarHBondContact O-CB 3.4Å; L586-N590 PolarHBondContact O-N 3.4Å; L586-N590 PolarHBondContact O-ND2 2.92Å; E588-N590 VanDerWaalsContact C-N 3.34Å; E588-N590 PolarHBondContact O-N 3.39Å; N590-I592 VanDerWaalsContact C-N 3.32Å; N590-I592 PolarHBondContact O-N 2.88Å; N590-M593 PolarHBondContact O-N 2.83Å; N590-N594 VanDerWaalsContact O-CB 3.28Å; N590-N594 WeakPolarHBondContact O-CB 3.36Å; N590-N594 PolarHBondContact O-N 3.49Å; N590-N594 PolarHBondContact O-ND2 3.3Å
591K82.5Confident82.8Confident107 Ų10798.5 Ų98.547%0.46548%0.479SS..Hα-helixtrans-62.6-36.4173.4-76.2165.4-168.3173.60112.8E587 E588 R595E587-K591 WeakPolarHBondContact O-CB 3.27Å; E587-K591 WeakPolarHBondContact O-CD 3.35Å; E587-K591 WeakPolarHBondContact O-CG 3.41Å; E587-K591 PolarHBondContact O-N 3.38Å; E588-K591 PolarHBondContact O-N 2.85Å; E588-K591 IonicContact OE1-NZ 2.75Å; E588-K591 PolarHBondContact OE1-NZ 3.47Å; E588-K591 WeakPolarHBondContact OE2-CD 3.33Å; E588-K591 IonicContact OE2-NZ 3.82Å; K591-R595 WeakPolarHBondContact O-CB 3.22Å; K591-R595 WeakPolarHBondContact O-CD 3.29Å; K591-R595 VanDerWaalsContact O-CG 3.27Å; K591-R595 WeakPolarHBondContact O-CG 3.35Å
592I82.9Confident82Confident82 Ų8295.3 Ų95.342%0.42146%0.464SS..Hα-helixtrans-71.8-51.6176.3-67.4167.5000109.5E588 K589 N590 N594 R595 S596 L607E588-I592 WeakPolarHBondContact O-CG1 3.33Å; E588-I592 PolarHBondContact O-N 3.06Å; K589-I592 PolarHBondContact O-N 2.91Å; N590-I592 VanDerWaalsContact C-N 3.32Å; N590-I592 PolarHBondContact O-N 2.88Å; I592-N594 PolarHBondContact O-N 2.73Å; I592-R595 CarbonylContact O-C 3.51Å; I592-R595 PolarHBondContact O-N 2.89Å; I592-S596 PolarHBondContact O-N 3.18Å; I592-S596 PolarHBondContact O-OG 3.4Å; I592-L607 HydrophobicContact CG2-CD2 4.12Å
593M82.3Confident81.4Confident111 Ų11196 Ų9655%0.54747%0.468SS..Hα-helixtrans-58.1-43.1-179.6-68.7-61.8-62.800113K589 N590 R595 S596K589-M593 VanDerWaalsContact O-CG 3.31Å; K589-M593 WeakPolarHBondContact O-CG 3.42Å; K589-M593 PolarHBondContact O-N 3.32Å; N590-M593 PolarHBondContact O-N 2.83Å; M593-R595 PolarHBondContact O-N 3.27Å; M593-S596 WeakPolarHBondContact CA-OG 3.37Å; M593-S596 PolarHBondContact O-N 2.89Å; M593-S596 PolarHBondContact O-OG 3.31Å
594N84.8Confident80.9Confident139 Ų13993.9 Ų93.974%0.74346%0.46SS*.THydrogen-bonded Turntrans-71.5-11.2178.1-68.5-11000113.6N590 I592N590-N594 VanDerWaalsContact O-CB 3.28Å; N590-N594 WeakPolarHBondContact O-CB 3.36Å; N590-N594 PolarHBondContact O-N 3.49Å; N590-N594 PolarHBondContact O-ND2 3.3Å; I592-N594 PolarHBondContact O-N 2.73Å
595R85.3Confident80.9Confident75 Ų7599.2 Ų99.228%0.28348%0.476SS..THydrogen-bonded Turntrans-107.4-15.4177.1-73.7175.155.4-133.3-12.1112.7K591 I592 M593 L607 H608 I610K591-R595 WeakPolarHBondContact O-CB 3.22Å; K591-R595 WeakPolarHBondContact O-CD 3.29Å; K591-R595 VanDerWaalsContact O-CG 3.27Å; K591-R595 WeakPolarHBondContact O-CG 3.35Å; I592-R595 CarbonylContact O-C 3.51Å; I592-R595 PolarHBondContact O-N 2.89Å; M593-R595 PolarHBondContact O-N 3.27Å; R595-L607 HydrophobicContact CB-CD2 4.08Å; R595-L607 CarbonylContact O-C 3.55Å; R595-L607 WeakPolarHBondContact O-CA 3.38Å; R595-H608 PolarHBondContact NE-O 3.36Å; R595-H608 VanDerWaalsContact NE-O 3.13Å; R595-H608 PolarHBondContact NH2-O 2.74Å; R595-H608 PolarHBondContact O-CD2 2.9Å; R595-H608 PolarHBondContact O-N 2.88Å; R595-I610 VanDerWaalsContact NH2-CG1 3.3Å
596S89.3Confident80.6Confident27 Ų2799 Ų9919%0.18947%0.468CS..EExtended strand (participates in β ladder)trans-81.9119.7177.256.90000110.1I592 M593 K606I592-S596 PolarHBondContact O-N 3.18Å; I592-S596 PolarHBondContact O-OG 3.4Å; M593-S596 WeakPolarHBondContact CA-OG 3.37Å; M593-S596 PolarHBondContact O-N 2.89Å; M593-S596 PolarHBondContact O-OG 3.31Å; S596-K606 WeakPolarHBondContact CA-O 3.22Å
597F88.6Confident80.8Confident71 Ų7198 Ų9831%0.31146%0.462SS..EExtended strand (participates in β ladder)trans-115150.416666.9-83.8000108.8D599 W605 K606 H608F597-D599 HydrophobicContact CE2-CB 4.22Å; F597-W605 WeakPolarHBondContact O-CA 3.43Å; F597-K606 HydrophobicContact CD1-CB 4.42Å; F597-K606 WeakPolarHBondContact CD1-O 3.33Å; F597-K606 HydrophobicContact CE1-CB 3.8Å; F597-K606 HydrophobicContact CE2-CB 3.98Å; F597-K606 HydrophobicContact CE2-CD 4.48Å; F597-K606 HydrophobicContact CZ-CB 3.56Å; F597-K606 HydrophobicContact CZ-CD 4.33Å; F597-K606 PolarHBondContact N-O 2.84Å; F597-K606 PolarHBondContact O-N 3.13Å; F597-H608 AromaticContact CD1-CD2 3.74Å; F597-H608 AromaticContact CD1-CE1 3.4Å; F597-H608 VanDerWaalsContact CD1-CE1 3.4Å; F597-H608 WeakPolarHBondContact CD1-CE1 3.45Å; F597-H608 AromaticContact CD1-CG 3.95Å; F597-H608 AromaticContact CD1-ND1 3.75Å; F597-H608 AromaticContact CD1-NE2 3.4Å; F597-H608 WeakPolarHBondContact CD1-NE2 3.42Å; F597-H608 AromaticContact CE1-CE1 3.59Å; F597-H608 AromaticContact CE1-ND1 3.6Å
598F86.1Confident80.7Confident87 Ų8796.9 Ų96.938%0.38246%0.457SS..EExtended strand (participates in β ladder)trans-86.8126.7171.3-170-106.4000108.7E600 D603 W605F598-E600 HydrophobicContact CD1-CG 4.06Å; F598-E600 HydrophobicContact CE1-CG 4.39Å; F598-D603 WeakPolarHBondContact CZ-OD1 3.5Å; F598-W605 HydrophobicContact CB-CD2 4.32Å; F598-W605 HydrophobicContact CB-CE3 4.21Å; F598-W605 HydrophobicContact CB-CH2 4.29Å; F598-W605 HydrophobicContact CB-CZ2 4.36Å; F598-W605 HydrophobicContact CB-CZ3 4.21Å; F598-W605 AromaticContact CD2-CD1 3.88Å; F598-W605 HydrophobicContact CD2-CD2 4.03Å; F598-W605 AromaticContact CD2-CE2 3.84Å; F598-W605 HydrophobicContact CD2-CG 4.08Å; F598-W605 HydrophobicContact CD2-CZ2 4.41Å; F598-W605 AromaticContact CD2-NE1 3.71Å
599D83.9Confident80.2Confident31 Ų3197.7 Ų97.717%0.16647%0.469CS..EExtended strand (participates in β ladder)trans-92.8104.6175.5-170.3-40000108.7F597 E601 E602 D603 Q604 K606F597-D599 HydrophobicContact CE2-CB 4.22Å; D599-E601 VanDerWaalsContact C-N 3.25Å; D599-E601 PolarHBondContact O-N 2.93Å; D599-E601 PolarHBondContact OD1-N 3.18Å; D599-E602 PolarHBondContact O-N 3.4Å; D599-E602 PolarHBondContact OD1-N 2.87Å; D599-D603 WeakPolarHBondContact O-CA 3.46Å; D599-D603 PolarHBondContact O-N 2.92Å; D599-Q604 WeakPolarHBondContact CB-O 3.4Å; D599-Q604 PolarHBondContact N-O 3.4Å; D599-Q604 PolarHBondContact O-N 3.43Å; D599-K606 HydrophobicContact CB-CD 3.91Å; D599-K606 HydrophobicContact CB-CG 4.31Å; D599-K606 WeakPolarHBondContact OD2-CD 3.31Å; D599-K606 VanDerWaalsContact OD2-CE 3.28Å; D599-K606 WeakPolarHBondContact OD2-CE 3.28Å; D599-K606 IonicContact OD2-NZ 3.97Å; D599-K606 PolarHBondContact OD2-NZ 3.36Å
600E76.8Confident79.5Confident176 Ų176101.7 Ų101.782%0.82249%0.492SS*.THydrogen-bonded Turntrans-68.7-19.1-178.2-66.6-173.9177.100113.6F598F598-E600 HydrophobicContact CD1-CG 4.06Å; F598-E600 HydrophobicContact CE1-CG 4.39Å
601E61.7Low78.1Confident168 Ų168103 Ų10379%0.78550%0.503SS*.THydrogen-bonded Turntrans-80.4-36.7176.8-64.6-167.4179.500111.7D599D599-E601 VanDerWaalsContact C-N 3.25Å; D599-E601 PolarHBondContact O-N 2.93Å; D599-E601 PolarHBondContact OD1-N 3.18Å
602E66.4Low76.7Confident49 Ų49109.2 Ų109.223%0.22952%0.524CS..THydrogen-bonded Turntrans-105.9-1.1-175.8-61.7-60.2154.700114.3K167 D599 Q604K167-E602 IonicContact NZ-OE1 2.72Å; K167-E602 PolarHBondContact NZ-OE1 2.72Å; D599-E602 PolarHBondContact O-N 3.4Å; D599-E602 PolarHBondContact OD1-N 2.87Å; E602-Q604 VanDerWaalsContact C-N 3.32Å; E602-Q604 WeakPolarHBondContact O-CG 3.21Å; E602-Q604 PolarHBondContact O-N 3.26Å
603D72.5Confident75.1Confident126 Ų126112.9 Ų112.967%0.67454%0.543SS*.THydrogen-bonded Turntrans58.537.1176.7-161.140.7000113.4F598 D599F598-D603 WeakPolarHBondContact CZ-OD1 3.5Å; D599-D603 WeakPolarHBondContact O-CA 3.46Å; D599-D603 PolarHBondContact O-N 2.92Å
604Q74.9Confident73.3Confident119 Ų119115 Ų11556%0.55656%0.557SS**EExtended strand (participates in β ladder)trans-140.5144.3-172.5-72.4179.522.900113.3D599 E602 K606D599-Q604 WeakPolarHBondContact CB-O 3.4Å; D599-Q604 PolarHBondContact N-O 3.4Å; D599-Q604 PolarHBondContact O-N 3.43Å; E602-Q604 VanDerWaalsContact C-N 3.32Å; E602-Q604 WeakPolarHBondContact O-CG 3.21Å; E602-Q604 PolarHBondContact O-N 3.26Å; Q604-K606 PolarHBondContact O-N 2.79Å
605W82.6Confident71.3Confident178 Ų178115.6 Ų115.667%0.67456%0.56SS**EExtended strand (participates in β ladder)trans-73.7116.2168.2-73.594.7000110.8F597 F598F597-W605 WeakPolarHBondContact O-CA 3.43Å; F598-W605 HydrophobicContact CB-CD2 4.32Å; F598-W605 HydrophobicContact CB-CE3 4.21Å; F598-W605 HydrophobicContact CB-CH2 4.29Å; F598-W605 HydrophobicContact CB-CZ2 4.36Å; F598-W605 HydrophobicContact CB-CZ3 4.21Å; F598-W605 AromaticContact CD2-CD1 3.88Å; F598-W605 HydrophobicContact CD2-CD2 4.03Å; F598-W605 AromaticContact CD2-CE2 3.84Å; F598-W605 HydrophobicContact CD2-CG 4.08Å; F598-W605 HydrophobicContact CD2-CZ2 4.41Å; F598-W605 AromaticContact CD2-NE1 3.71Å
606K83.3Confident69.6Low72 Ų72121.7 Ų121.731%0.31359%0.592SS.*EExtended strand (participates in β ladder)trans-110.1146.9177.1-67.4-178.4-173.6170.90110.3S596 F597 D599 Q604S596-K606 WeakPolarHBondContact CA-O 3.22Å; F597-K606 HydrophobicContact CD1-CB 4.42Å; F597-K606 WeakPolarHBondContact CD1-O 3.33Å; F597-K606 HydrophobicContact CE1-CB 3.8Å; F597-K606 HydrophobicContact CE2-CB 3.98Å; F597-K606 HydrophobicContact CE2-CD 4.48Å; F597-K606 HydrophobicContact CZ-CB 3.56Å; F597-K606 HydrophobicContact CZ-CD 4.33Å; F597-K606 PolarHBondContact N-O 2.84Å; F597-K606 PolarHBondContact O-N 3.13Å; D599-K606 HydrophobicContact CB-CD 3.91Å; D599-K606 HydrophobicContact CB-CG 4.31Å; D599-K606 WeakPolarHBondContact OD2-CD 3.31Å; D599-K606 VanDerWaalsContact OD2-CE 3.28Å; D599-K606 WeakPolarHBondContact OD2-CE 3.28Å; D599-K606 IonicContact OD2-NZ 3.97Å; D599-K606 PolarHBondContact OD2-NZ 3.36Å; Q604-K606 PolarHBondContact O-N 2.79Å
607L84.1Confident67.6Low90 Ų90128.4 Ų128.447%0.47162%0.62SS.*EExtended strand (participates in β ladder)trans-99.9129.7175.5-71171.4000110.4I592 R595I592-L607 HydrophobicContact CG2-CD2 4.12Å; R595-L607 HydrophobicContact CB-CD2 4.08Å; R595-L607 CarbonylContact O-C 3.55Å; R595-L607 WeakPolarHBondContact O-CA 3.38Å
608H80.8Confident65.7Low99 Ų99133.8 Ų133.846%0.45865%0.649SS.*PPolyproline II helixtrans-56.4131.4170.2-73.1-61.7000110.9R595 F597R595-H608 PolarHBondContact NE-O 3.36Å; R595-H608 VanDerWaalsContact NE-O 3.13Å; R595-H608 PolarHBondContact NH2-O 2.74Å; R595-H608 PolarHBondContact O-CD2 2.9Å; R595-H608 PolarHBondContact O-N 2.88Å; F597-H608 AromaticContact CD1-CD2 3.74Å; F597-H608 AromaticContact CD1-CE1 3.4Å; F597-H608 VanDerWaalsContact CD1-CE1 3.4Å; F597-H608 WeakPolarHBondContact CD1-CE1 3.45Å; F597-H608 AromaticContact CD1-CG 3.95Å; F597-H608 AromaticContact CD1-ND1 3.75Å; F597-H608 AromaticContact CD1-NE2 3.4Å; F597-H608 WeakPolarHBondContact CD1-NE2 3.42Å; F597-H608 AromaticContact CE1-CE1 3.59Å; F597-H608 AromaticContact CE1-ND1 3.6Å
609P69.5Low64Low104 Ų104138.4 Ų138.468%0.67567%0.674SS**PPolyproline II helixtrans-55.7144.5177-27.535.8000113T611P609-T611 PolarHBondContact O-N 2.87Å
610I66.8Low62.5Low140 Ų140146.7 Ų146.772%0.71871%0.708SS**  trans-73.7-13.9-179.2-58.2176.5000111.9R595 R612R595-I610 VanDerWaalsContact NH2-CG1 3.3Å; I610-R612 PolarHBondContact O-N 3.29Å
611T56.2Low61.3Low111 Ų111149 Ų14968%0.68171%0.709SS**  trans-61.8110.9-176.8390000111.9P609 L613P609-T611 PolarHBondContact O-N 2.87Å; T611-L613 PolarHBondContact O-N 2.85Å; T611-L613 VanDerWaalsContact O-N 3.09Å
612R51.8Low61Low239 Ų239145.9 Ų145.990%0.90270%0.704SS**  trans-51114.7154.3-74.5-179.6172.3175.3-4.2107.9I610 D614I610-R612 PolarHBondContact O-N 3.29Å; R612-D614 PolarHBondContact O-N 2.86Å
613L49.1Very low60.5Low158 Ų158150 Ų15083%0.82773%0.732SS**THydrogen-bonded Turntrans-60.4119.3165.5-70152.5000107.1T611T611-L613 PolarHBondContact O-N 2.85Å; T611-L613 VanDerWaalsContact O-N 3.09Å
614D44.8Very low59.7Low156 Ų156145.2 Ų145.283%0.83471%0.708SS**THydrogen-bonded Turntrans159.1-4.4150.8-84.8-4.2000114.8R612R612-D614 PolarHBondContact O-N 2.86Å
615N42.7Very low58.7Low151 Ų151144.6 Ų144.681%0.80772%0.723SS**  trans-142.9113.9168.7-97.4-60.3000113.8Q617N615-Q617 PolarHBondContact O-N 3.41Å
616Q50.8Low57.6Low204 Ų204140.6 Ų140.695%0.95372%0.719SS**  trans-75.258.6173.2-72.2-173.9-16.400112.7
617Q47.2Very low56.6Low167 Ų167141.4 Ų141.478%0.7875%0.747SS**  trans-13097.9159.6-74.7-168.40.300109.8N615 M619N615-Q617 PolarHBondContact O-N 3.41Å; Q617-M619 PolarHBondContact O-N 3.37Å
618M48.8Very low55.6Low185 Ų185143.2 Ų143.291%0.91175%0.749SS**  trans-56.6112155.3-67.5179.572.700107.1K620M618-K620 PolarHBondContact O-N 2.84Å
619M49.2Very low54.6Low184 Ų184146.5 Ų146.591%0.90676%0.762SS**  trans-56.4100.9176.8-74.4-104.9-8300109.2Q617 R621Q617-M619 PolarHBondContact O-N 3.37Å; M619-R621 PolarHBondContact O-N 3.42Å
620K52.8Low54.4Low204 Ų204147.1 Ų147.189%0.88775%0.75SS**PPolyproline II helixtrans-58.6123.2172.8-80.3-175.2175.8178.20107.3M618M618-K620 PolarHBondContact O-N 2.84Å
621R52.1Low54.2Low225 Ų225144.3 Ų144.385%0.84974%0.742SS**PPolyproline II helixtrans-55.5131.1175.3-74.1-174.9173-168.4-1108.6M619 V623M619-R621 PolarHBondContact O-N 3.42Å; R621-V623 PolarHBondContact O-N 3.01Å; R621-V623 VanDerWaalsContact O-N 3.16Å
622P55Low54.7Low103 Ų103140.6 Ų140.667%0.66972%0.717SS**PPolyproline II helixtrans-61.9120.7179.224.2-32.8000109.6
623V56.8Low55.7Low136 Ų136132.7 Ų132.782%0.82470%0.699SS**PPolyproline II helixtrans-72.9143174.1-81.20000110.2R621R621-V623 PolarHBondContact O-N 3.01Å; R621-V623 VanDerWaalsContact O-N 3.16Å
624S54.5Low56.9Low25 Ų25132.4 Ų132.418%0.17569%0.693CS.*PPolyproline II helixtrans-70.6139.3174.3-158.90000110.2V626 Y628 R630 P631S624-V626 PolarHBondContact O-N 3.48Å; S624-V626 VanDerWaalsContact O-N 3.11Å; S624-Y628 WeakPolarHBondContact CB-O 3.17Å; S624-R630 VanDerWaalsContact CB-O 3.25Å; S624-R630 WeakPolarHBondContact CB-O 3.44Å; S624-R630 PolarHBondContact OG-O 2.94Å; S624-P631 WeakPolarHBondContact OG-CA 3.37Å
625A54.9Low58.5Low106 Ų106131 Ų13188%0.87668%0.682SS**SBendtrans-67.2-9.9-179.700000114.2
626V59.4Low59.9Low94 Ų94124.3 Ų124.357%0.5765%0.647SS**SBendtrans-144.679.9-175.2-164.10000111.2S624 Y628S624-V626 PolarHBondContact O-N 3.48Å; S624-V626 VanDerWaalsContact O-N 3.11Å; V626-Y628 WeakPolarHBondContact O-CD2 3.45Å; V626-Y628 PolarHBondContact O-N 3.44Å
627G61.7Low60.9Low89 Ų89120.2 Ų120.292%0.91862%0.622SS**SBendtrans66.2-22.2162.800000119.4
628Y62.7Low62.2Low128 Ų128115.8 Ų115.850%0.50261%0.607SS.*SBendtrans-83.8151-178.6-65.6-73.5000112.2S624 V626 R630 A650S624-Y628 WeakPolarHBondContact CB-O 3.17Å; V626-Y628 WeakPolarHBondContact O-CD2 3.45Å; V626-Y628 PolarHBondContact O-N 3.44Å; Y628-R630 PolarHBondContact O-N 3.49Å; Y628-R630 VanDerWaalsContact O-N 3.08Å; Y628-A650 HydrophobicContact CD1-CB 3.66Å; Y628-A650 HydrophobicContact CE1-CB 4.33Å; Y628-A650 HydrophobicContact CG-CB 4.13Å
629K60Low63.6Low168 Ų168108.1 Ų108.173%0.7357%0.572SS**SBendtrans-68.1-6.7179-64.2174.7-169.2143.30114.3E651K629-E651 IonicContact NZ-OE1 3.17Å; K629-E651 PolarHBondContact NZ-OE1 3.44Å
630R64.8Low64.7Low116 Ų116102.4 Ų102.444%0.43854%0.543SS..SBendtrans-144.8149.6179.4-63.5-176.6-179.2-177.41111.6S624 Y628 N652S624-R630 VanDerWaalsContact CB-O 3.25Å; S624-R630 WeakPolarHBondContact CB-O 3.44Å; S624-R630 PolarHBondContact OG-O 2.94Å; Y628-R630 PolarHBondContact O-N 3.49Å; Y628-R630 VanDerWaalsContact O-N 3.08Å; R630-N652 PolarHBondContact NH1-ND2 2.62Å; R630-N652 VanDerWaalsContact NH1-ND2 3.15Å; R630-N652 PolarHBondContact NH1-OD1 3.12Å
631P63.6Low65.5Low82 Ų82101 Ų10153%0.53254%0.542SS..  trans-63.5135.3170.8-20.833.3000112.1S624S624-P631 WeakPolarHBondContact OG-CA 3.37Å
632L66Low66.6Low32 Ų3296.7 Ų96.717%0.16854%0.535CS..  trans-122.2135.8175.4-77.1178.3000111.7A636 R637 M640 A650L632-A636 HydrophobicContact CD2-CB 4.38Å; L632-R637 HydrophobicContact CB-CG 4.32Å; L632-R637 PolarHBondContact O-NE 2.97Å; L632-R637 PolarHBondContact O-NH2 3.34Å; L632-M640 HydrophobicContact CD1-SD 4.46Å; L632-A650 HydrophobicContact CD1-CB 3.79Å; L632-A650 HydrophobicContact CG-CB 4.48Å
633S73.5Confident67.1Low74 Ų7499.7 Ų99.752%0.51753%0.533SS..  trans-64.5156.8172.371.80000111.2H635 A636 R637S633-H635 VanDerWaalsContact C-N 3.31Å; S633-H635 PolarHBondContact O-N 3.3Å; S633-A636 PolarHBondContact O-N 2.95Å; S633-A636 WeakPolarHBondContact OG-CB 3.27Å; S633-A636 PolarHBondContact OG-N 3.28Å; S633-R637 PolarHBondContact O-N 3.38Å
634Q74.3Confident67.4Low152 Ų15297.9 Ų97.971%0.7152%0.523SS*.Hα-helixtrans-65-37.4178.4-169.7171-1.300111.5A636 R637 T638Q634-A636 PolarHBondContact O-N 2.83Å; Q634-R637 PolarHBondContact O-N 2.91Å; Q634-T638 PolarHBondContact O-N 3.47Å; Q634-T638 VanDerWaalsContact O-N 3.08Å; Q634-T638 PolarHBondContact O-OG1 3.3Å
635H77.6Confident67.9Low127 Ų127100.1 Ų100.159%0.58853%0.531SS*.Hα-helixtrans-58.7-46.7174.2-178.782.4000112.3S633 R637 T638 S639S633-H635 VanDerWaalsContact C-N 3.31Å; S633-H635 PolarHBondContact O-N 3.3Å; H635-R637 VanDerWaalsContact C-N 3.29Å; H635-R637 PolarHBondContact O-N 3.36Å; H635-T638 PolarHBondContact O-N 2.96Å; H635-S639 PolarHBondContact O-N 3.48Å; H635-S639 PolarHBondContact O-OG 2.94Å
636A71.6Confident68.4Low9 Ų998.4 Ų98.47%0.07452%0.517CS..Hα-helixtrans-61.1-37.7177.900000112.4L632 S633 Q634 M640 Y648L632-A636 HydrophobicContact CD2-CB 4.38Å; S633-A636 PolarHBondContact O-N 2.95Å; S633-A636 WeakPolarHBondContact OG-CB 3.27Å; S633-A636 PolarHBondContact OG-N 3.28Å; Q634-A636 PolarHBondContact O-N 2.83Å; A636-M640 WeakPolarHBondContact O-CG 3.23Å; A636-M640 PolarHBondContact O-N 2.96Å; A636-Y648 HydrophobicContact CB-CD1 4.2Å
637R71.9Confident68.7Low118 Ų118102.9 Ų102.945%0.44552%0.524SS..Hα-helixtrans-64.3-46.9176.2-73.2180-107.7170-8.1112.4L632 S633 Q634 H635 M640 M641L632-R637 HydrophobicContact CB-CG 4.32Å; L632-R637 PolarHBondContact O-NE 2.97Å; L632-R637 PolarHBondContact O-NH2 3.34Å; S633-R637 PolarHBondContact O-N 3.38Å; Q634-R637 PolarHBondContact O-N 2.91Å; H635-R637 VanDerWaalsContact C-N 3.29Å; H635-R637 PolarHBondContact O-N 3.36Å; R637-M640 PolarHBondContact O-N 2.99Å; R637-M641 PolarHBondContact O-N 3.45Å
638T75.8Confident69Low74 Ų74100.9 Ų100.945%0.45449%0.489SS..Hα-helixtrans-64.8-42.5177.5-48.40000111.2Q634 H635 M640 M641 I642Q634-T638 PolarHBondContact O-N 3.47Å; Q634-T638 VanDerWaalsContact O-N 3.08Å; Q634-T638 PolarHBondContact O-OG1 3.3Å; H635-T638 PolarHBondContact O-N 2.96Å; T638-M640 PolarHBondContact O-N 3.37Å; T638-M641 PolarHBondContact O-N 3.44Å; T638-I642 HydrophobicContact CG2-CD1 4.03Å; T638-I642 PolarHBondContact O-N 3.25Å
639S77.6Confident69.1Low25 Ų2599.4 Ų99.418%0.17548%0.482CS..Hα-helixtrans-61.9-41.7177.1-66.10000112.3H635 M641 I642 R643H635-S639 PolarHBondContact O-N 3.48Å; H635-S639 PolarHBondContact O-OG 2.94Å; S639-M641 VanDerWaalsContact C-N 3.26Å; S639-M641 PolarHBondContact O-N 2.93Å; S639-I642 PolarHBondContact O-N 3.24Å; S639-I642 VanDerWaalsContact O-N 3.12Å; S639-R643 CarbonylContact O-C 3.58Å; S639-R643 PolarHBondContact O-N 3.49Å
640M71.9Confident69.2Low63 Ų6391.9 Ų91.931%0.3145%0.452SS..Hα-helixtrans-57.9-34.2175.6-79.6-174.472.900113.8L632 A636 R637 T638 Y648 R649L632-M640 HydrophobicContact CD1-SD 4.46Å; A636-M640 WeakPolarHBondContact O-CG 3.23Å; A636-M640 PolarHBondContact O-N 2.96Å; R637-M640 PolarHBondContact O-N 2.99Å; T638-M640 PolarHBondContact O-N 3.37Å; M640-Y648 WeakPolarHBondContact CG-O 3.47Å; M640-R649 HydrophobicContact CE-CG 4.49Å
641M69.9Low69.2Low174 Ų17490.3 Ų90.386%0.85745%0.449SS*.Hα-helixtrans-75.1-25.5178.6-70.3-179.6168.300113.2R637 T638 S639R637-M641 PolarHBondContact O-N 3.45Å; T638-M641 PolarHBondContact O-N 3.44Å; S639-M641 VanDerWaalsContact C-N 3.26Å; S639-M641 PolarHBondContact O-N 2.93Å
642I74.9Confident68.9Low135 Ų13592.5 Ų92.569%0.69246%0.457SS*.Hα-helixtrans-95.6-38.9-177.4-61.4170000111.1T638 S639T638-I642 HydrophobicContact CG2-CD1 4.03Å; T638-I642 PolarHBondContact O-N 3.25Å; S639-I642 PolarHBondContact O-N 3.24Å; S639-I642 VanDerWaalsContact O-N 3.12Å
643R66.3Low68.6Low167 Ų16795.9 Ų95.963%0.6347%0.474SS*.  trans-145.1122.2173.5-84.9-170.6177.61720.8111.2S639 E645S639-R643 CarbonylContact O-C 3.58Å; S639-R643 PolarHBondContact O-N 3.49Å; R643-E645 HydrophobicContact CB-CG 4.26Å; R643-E645 WeakPolarHBondContact CD-OE1 3.21Å; R643-E645 IonicContact NH1-OE1 3.29Å; R643-E645 PolarHBondContact O-N 3.39Å
644P63.3Low67.7Low97 Ų9797.7 Ų97.763%0.6348%0.481SS*.  trans-78.744.8-179.433.5-36.7000113.7R649P644-R649 PolarHBondContact O-NH2 3.29Å
645E65.1Low66.7Low72 Ų7296.5 Ų96.534%0.33648%0.48SS..  trans-62.4135.3176.8-73.4174.7-157.800111.3R643 R647 Y648R643-E645 HydrophobicContact CB-CG 4.26Å; R643-E645 WeakPolarHBondContact CD-OE1 3.21Å; R643-E645 IonicContact NH1-OE1 3.29Å; R643-E645 PolarHBondContact O-N 3.39Å; E645-R647 HydrophobicContact CB-CG 4.19Å; E645-R647 PolarHBondContact O-N 3.02Å; E645-Y648 HydrophobicContact CB-CD2 4.1Å; E645-Y648 HydrophobicContact CB-CE2 4.44Å; E645-Y648 PolarHBondContact O-N 2.94Å; E645-Y648 VanDerWaalsContact O-N 3.14Å
646A64.4Low65.6Low71 Ų7197.1 Ų97.159%0.58749%0.486SS*.G310 helixtrans-55.5-31.6-174.500000113.7Y648 R649A646-Y648 PolarHBondContact O-N 3.34Å; A646-R649 PolarHBondContact O-N 2.99Å
647R65.2Low64.6Low188 Ų188105.4 Ų105.471%0.70952%0.524SS*.G310 helixtrans-63.5-17.2-178.972.4-176.8-64.3-1743.5115.3E645E645-R647 HydrophobicContact CB-CG 4.19Å; E645-R647 PolarHBondContact O-N 3.02Å
648Y68Low63.5Low47 Ų47106.8 Ų106.818%0.18454%0.539CS..G310 helixtrans-107.6-3.2-178.5-59.3-64000113.5A636 M640 E645 A646A636-Y648 HydrophobicContact CB-CD1 4.2Å; M640-Y648 WeakPolarHBondContact CG-O 3.47Å; E645-Y648 HydrophobicContact CB-CD2 4.1Å; E645-Y648 HydrophobicContact CB-CE2 4.44Å; E645-Y648 PolarHBondContact O-N 2.94Å; E645-Y648 VanDerWaalsContact O-N 3.14Å; A646-Y648 PolarHBondContact O-N 3.34Å
649R66.4Low62.3Low96 Ų96110.7 Ų110.736%0.36256%0.557SS.*  trans-67.9147.2-176.9-64.7-175.3-178.5-168.40112.2M640 P644 A646 E651M640-R649 HydrophobicContact CE-CG 4.49Å; P644-R649 PolarHBondContact O-NH2 3.29Å; A646-R649 PolarHBondContact O-N 2.99Å; R649-E651 VanDerWaalsContact C-N 3.25Å; R649-E651 PolarHBondContact O-N 2.96Å
650A62.2Low60.8Low11 Ų11116.8 Ų116.89%0.09159%0.585CS.*SBendtrans-66.1-25.4177.600000114.1Y628 L632Y628-A650 HydrophobicContact CD1-CB 3.66Å; Y628-A650 HydrophobicContact CE1-CB 4.33Å; Y628-A650 HydrophobicContact CG-CB 4.13Å; L632-A650 HydrophobicContact CD1-CB 3.79Å; L632-A650 HydrophobicContact CG-CB 4.48Å
651E63.3Low59.9Low82 Ų82118.4 Ų118.438%0.38360%0.6SS.*SBendtrans-116.7132-174.8-55.5-162139.300109.9K629 R649 I653K629-E651 IonicContact NZ-OE1 3.17Å; K629-E651 PolarHBondContact NZ-OE1 3.44Å; R649-E651 VanDerWaalsContact C-N 3.25Å; R649-E651 PolarHBondContact O-N 2.96Å; E651-I653 HydrophobicContact CB-CD1 4.32Å; E651-I653 HydrophobicContact CB-CG1 4.21Å; E651-I653 PolarHBondContact O-N 3.3Å
652N57.6Low59.2Low128 Ų128115.3 Ų115.368%0.68460%0.595SS**  trans-77.748.5175.6-69.317.9000111R630R630-N652 PolarHBondContact NH1-ND2 2.62Å; R630-N652 VanDerWaalsContact NH1-ND2 3.15Å; R630-N652 PolarHBondContact NH1-OD1 3.12Å
653I59.1Low58.1Low103 Ų103119.3 Ų119.353%0.52860%0.602SS.*  trans-105106175.8-58.4177.5000106.7E651 L655E651-I653 HydrophobicContact CB-CD1 4.32Å; E651-I653 HydrophobicContact CB-CG1 4.21Å; E651-I653 PolarHBondContact O-N 3.3Å; I653-L655 HydrophobicContact CG2-CG 4.49Å; I653-L655 PolarHBondContact O-N 3.28Å; I653-L655 VanDerWaalsContact O-N 3.14Å
654V55.1Low57.5Low112 Ų112117.1 Ų117.168%0.67961%0.607SS**  trans-76.398.5169.5-171.60000106.9L656V654-L656 VanDerWaalsContact C-N 3.26Å; V654-L656 HydrophobicContact CG1-CD2 3.85Å; V654-L656 HydrophobicContact CG1-CG 3.92Å; V654-L656 PolarHBondContact O-N 3.2Å
655L53.7Low57Low128 Ų128117.7 Ų117.767%0.6761%0.609SS**  trans-70.490.5165-87.1147.9000107.6I653 E657I653-L655 HydrophobicContact CG2-CG 4.49Å; I653-L655 PolarHBondContact O-N 3.28Å; I653-L655 VanDerWaalsContact O-N 3.14Å; L655-E657 PolarHBondContact O-N 2.87Å
656L53.9Low56.6Low140 Ų140123.8 Ų123.873%0.73363%0.629SS**  trans-75.297.3162.1-65173.2000106.8V654 L658V654-L656 VanDerWaalsContact C-N 3.26Å; V654-L656 HydrophobicContact CG1-CD2 3.85Å; V654-L656 HydrophobicContact CG1-CG 3.92Å; V654-L656 PolarHBondContact O-N 3.2Å; L656-L658 PolarHBondContact O-N 3.13Å; L656-L658 VanDerWaalsContact O-N 3.08Å
657E52.1Low56.4Low183 Ų183126.9 Ų126.986%0.85564%0.636SS**  trans-63.7108.1157.9-74.3178.917100106.5L655 D659L655-E657 PolarHBondContact O-N 2.87Å; E657-D659 PolarHBondContact O-N 2.83Å
658L48.6Very low55.8Low146 Ų146127.5 Ų127.576%0.76464%0.639SS**  trans-7187.4174.2-93156.2000107.9L656 M660L656-L658 PolarHBondContact O-N 3.13Å; L656-L658 VanDerWaalsContact O-N 3.08Å; L658-M660 VanDerWaalsContact C-N 3.31Å; L658-M660 PolarHBondContact O-N 3.07Å
659D50Low55.2Low156 Ų156132.3 Ų132.383%0.83466%0.664SS**  trans-65.295.1167.5-155.517.7000107.3E657 P661E657-D659 PolarHBondContact O-N 2.83Å; D659-P661 WeakPolarHBondContact O-CD 3.49Å
660M47Very low55Low154 Ų154129.7 Ų129.776%0.75967%0.666SS**  trans-68112.4-171.7-77.6-72-70.900109.4L658L658-M660 VanDerWaalsContact C-N 3.31Å; L658-M660 PolarHBondContact O-N 3.07Å
661P52.5Low54.9Low97 Ų97134 Ų13463%0.6369%0.693SS**  trans-66.1142.9-179.5-16.530.7000110.2D659 R663D659-P661 WeakPolarHBondContact O-CD 3.49Å; P661-R663 PolarHBondContact O-N 3.49Å
662S55.8Low54.8Low109 Ų109134.9 Ų134.976%0.76272%0.715SS**SBendtrans-57.7125.1158.143.30000108.2T664S662-T664 VanDerWaalsContact O-CG2 3.32Å; S662-T664 WeakPolarHBondContact O-CG2 3.4Å; S662-T664 PolarHBondContact O-N 3.48Å
663R51.5Low54.8Low218 Ų218133.2 Ų133.282%0.82371%0.705SS**SBendtrans-35.4106-167.9-178.3-175.3175.2-168.3-0.6114.2P661P661-R663 PolarHBondContact O-N 3.49Å
664T53.5Low55Low121 Ų121131 Ų13174%0.74270%0.702SS**  trans-124.929.1177.3460000113.5S662S662-T664 VanDerWaalsContact O-CG2 3.32Å; S662-T664 WeakPolarHBondContact O-CG2 3.4Å; S662-T664 PolarHBondContact O-N 3.48Å
665T53.2Low55.5Low110 Ų110131 Ų13168%0.67570%0.704SS**PPolyproline II helixtrans-88.7118.9170.143.50000111.4
666R54.7Low55.6Low200 Ų200133.7 Ų133.776%0.75571%0.71SS**PPolyproline II helixtrans-73145.1150.9178.4176.7169.3-179.2-6.5107.5E669R666-E669 IonicContact CZ-OE1 3.17Å; R666-E669 IonicContact NE-OE1 2.75Å; R666-E669 IonicContact NH2-OE1 3.93Å; R666-E669 PolarHBondContact NH2-OE1 3.22Å; R666-E669 IonicContact NH2-OE2 3.39Å
667D60.4Low55.9Low136 Ų136130.8 Ų130.873%0.72770%0.698SS**PPolyproline II helixtrans-60.5146.4-179-61.6-53.8000112E669D667-E669 PolarHBondContact O-N 3.02Å; D667-E669 VanDerWaalsContact O-N 3.12Å
668Y53.3Low56.6Low200 Ų200126.3 Ų126.378%0.78468%0.677SS**  trans-77.497.1-174.7177-103.5000111.3G670 P671Y668-G670 VanDerWaalsContact CE1-CA 3.41Å; Y668-G670 PolarHBondContact O-N 3.15Å; Y668-P671 VanDerWaalsContact OH-CD 3.27Å; Y668-P671 WeakPolarHBondContact OH-CD 3.43Å
669E54.6Low57.5Low149 Ų149121.9 Ų121.970%0.69666%0.662SS**  trans-74.2102.4157.3-69.9167.8-138.400107.6R666 D667R666-E669 IonicContact CZ-OE1 3.17Å; R666-E669 IonicContact NE-OE1 2.75Å; R666-E669 IonicContact NH2-OE1 3.93Å; R666-E669 PolarHBondContact NH2-OE1 3.22Å; R666-E669 IonicContact NH2-OE2 3.39Å; D667-E669 PolarHBondContact O-N 3.02Å; D667-E669 VanDerWaalsContact O-N 3.12Å
670G63Low58.1Low40 Ų40117.3 Ų117.341%0.41265%0.646SS.*  trans-63.8158.8178.800000112.7Y668 A672Y668-G670 VanDerWaalsContact CE1-CA 3.41Å; Y668-G670 PolarHBondContact O-N 3.15Å; G670-A672 PolarHBondContact O-N 2.91Å
671P59.8Low58.6Low102 Ų102114.7 Ų114.766%0.66263%0.634SS**  trans-59.1130.6176.126.7-33.7000109.3Y668 I673Y668-P671 VanDerWaalsContact OH-CD 3.27Å; Y668-P671 WeakPolarHBondContact OH-CD 3.43Å; P671-I673 PolarHBondContact O-N 2.9Å
672A60.6Low59.3Low101 Ų101115.4 Ų115.484%0.83563%0.629SS**  trans-57.2107.6176.300000109.2G670 A674G670-A672 PolarHBondContact O-N 2.91Å; A672-A674 PolarHBondContact O-N 3.27Å
673I58.8Low59.7Low92 Ų92113.5 Ų113.547%0.47262%0.62SS.*  trans-58.2126.4176.3-60.1175.6000106.3P671 V677 Q678P671-I673 PolarHBondContact O-N 2.9Å; I673-V677 HydrophobicContact CG2-CB 3.78Å; I673-V677 HydrophobicContact CG2-CG1 3.82Å; I673-Q678 HydrophobicContact CB-CB 4.36Å; I673-Q678 HydrophobicContact CG2-CB 3.9Å
674A63.4Low59.9Low56 Ų56106.7 Ų106.746%0.46361%0.61SS.*  trans-53.8131.6-179.500000108.8A672 K676 V677 Q678A672-A674 PolarHBondContact O-N 3.27Å; A674-K676 PolarHBondContact O-N 3.1Å; A674-V677 HydrophobicContact CB-CG2 4.29Å; A674-V677 WeakPolarHBondContact O-CA 3.29Å; A674-V677 WeakPolarHBondContact O-CB 3.44Å; A674-V677 PolarHBondContact O-N 2.89Å; A674-Q678 PolarHBondContact O-N 2.63Å; A674-Q678 VanDerWaalsContact O-N 3.15Å
675P64.5Low60Low112 Ų112106 Ų10673%0.72760%0.602SS**Hα-helixtrans-54.7-28.3-169.5-31.535.7000114.7A679P675-A679 WeakPolarHBondContact O-CB 3.47Å; P675-A679 PolarHBondContact O-N 2.97Å
676K57.1Low60.1Low185 Ų185108.1 Ų108.180%0.80460%0.604SS**Hα-helixtrans-65.9-37.3171.9-74.7-174.8172.2-177.30114.3A674 A680A674-K676 PolarHBondContact O-N 3.1Å; K676-A680 WeakPolarHBondContact O-CB 3.18Å; K676-A680 PolarHBondContact O-N 2.89Å
677V60.2Low60Low79 Ų79104.4 Ų104.448%0.47960%0.599SS.*Hα-helixtrans-75.5-38178.2179.20000110.1I673 A674 A680 L681I673-V677 HydrophobicContact CG2-CB 3.78Å; I673-V677 HydrophobicContact CG2-CG1 3.82Å; A674-V677 HydrophobicContact CB-CG2 4.29Å; A674-V677 WeakPolarHBondContact O-CA 3.29Å; A674-V677 WeakPolarHBondContact O-CB 3.44Å; A674-V677 PolarHBondContact O-N 2.89Å; V677-A680 PolarHBondContact O-N 2.89Å; V677-L681 HydrophobicContact CG1-CD1 4.19Å; V677-L681 WeakPolarHBondContact O-CD1 3.18Å; V677-L681 PolarHBondContact O-N 2.87Å
678Q67.3Low59.4Low90 Ų90107.1 Ų107.142%0.42161%0.607SS.*Hα-helixtrans-66.7-46.9174.2-171.3165.8-10.200111.4I673 A674 A680 L681 E682I673-Q678 HydrophobicContact CB-CB 4.36Å; I673-Q678 HydrophobicContact CG2-CB 3.9Å; A674-Q678 PolarHBondContact O-N 2.63Å; A674-Q678 VanDerWaalsContact O-N 3.15Å; Q678-A680 VanDerWaalsContact C-N 3.29Å; Q678-A680 PolarHBondContact O-N 3.15Å; Q678-L681 VanDerWaalsContact O-N 3.14Å; Q678-L681 PolarHBondContact O-N 3.19Å; Q678-E682 PolarHBondContact O-N 3.04Å
679A65.9Low58.8Low53 Ų53105 Ų10544%0.43861%0.609SS.*Hα-helixtrans-63.3-32.4174.100000113P675 A683P675-A679 WeakPolarHBondContact O-CB 3.47Å; P675-A679 PolarHBondContact O-N 2.97Å; A679-A683 WeakPolarHBondContact O-CB 3.48Å; A679-A683 PolarHBondContact O-N 2.81Å
680A62.8Low58.1Low60 Ų60105.4 Ų105.450%0.49661%0.612SS.*Hα-helixtrans-71.8-34.2173.400000112.6K676 V677 Q678 A684K676-A680 WeakPolarHBondContact O-CB 3.18Å; K676-A680 PolarHBondContact O-N 2.89Å; V677-A680 PolarHBondContact O-N 2.89Å; Q678-A680 VanDerWaalsContact C-N 3.29Å; Q678-A680 PolarHBondContact O-N 3.15Å; A680-A684 WeakPolarHBondContact O-CB 3.49Å; A680-A684 PolarHBondContact O-N 2.88Å; A680-A684 VanDerWaalsContact O-N 3.13Å
681L58.7Low57Low99 Ų99110.9 Ų110.952%0.51863%0.63SS.*Hα-helixtrans-67.9-47.5170.3-105.692.3000111.2V677 Q678 A684 L685V677-L681 HydrophobicContact CG1-CD1 4.19Å; V677-L681 WeakPolarHBondContact O-CD1 3.18Å; V677-L681 PolarHBondContact O-N 2.87Å; Q678-L681 VanDerWaalsContact O-N 3.14Å; Q678-L681 PolarHBondContact O-N 3.19Å; L681-A684 VanDerWaalsContact O-N 3.16Å; L681-A684 PolarHBondContact O-N 3.11Å; L681-A684 CarbonylContact O-C 3.49Å; L681-L685 HydrophobicContact CB-CD1 4.48Å; L681-L685 HydrophobicContact CD2-CD1 4.37Å; L681-L685 VanDerWaalsContact O-CB 3.23Å; L681-L685 WeakPolarHBondContact O-CB 3.46Å; L681-L685 WeakPolarHBondContact O-CD1 3.19Å; L681-L685 WeakPolarHBondContact O-CG 3.16Å; L681-L685 PolarHBondContact O-N 3.34Å
682E65.6Low55.7Low112 Ų112113.5 Ų113.552%0.52363%0.633SS.*Hα-helixtrans-62.9-43.8179.2-75.5173.916500111.5Q678 A684 L685 Q686Q678-E682 PolarHBondContact O-N 3.04Å; E682-A684 VanDerWaalsContact C-N 3.26Å; E682-A684 PolarHBondContact O-N 3.24Å; E682-L685 CarbonylContact O-C 3.5Å; E682-L685 VanDerWaalsContact O-N 3.11Å; E682-L685 PolarHBondContact O-N 3.34Å; E682-Q686 PolarHBondContact O-N 2.92Å
683A64.9Low54.6Low68 Ų68114.1 Ų114.156%0.56263%0.626SS**Hα-helixtrans-67.8-22.6174.700000113.8A679A679-A683 WeakPolarHBondContact O-CB 3.48Å; A679-A683 PolarHBondContact O-N 2.81Å
684A54.7Low53.4Low76 Ų76115.3 Ų115.363%0.62863%0.634SS**Hα-helixtrans-91.1-6.117300000113.6A680 L681 E682A680-A684 WeakPolarHBondContact O-CB 3.49Å; A680-A684 PolarHBondContact O-N 2.88Å; A680-A684 VanDerWaalsContact O-N 3.13Å; L681-A684 VanDerWaalsContact O-N 3.16Å; L681-A684 PolarHBondContact O-N 3.11Å; L681-A684 CarbonylContact O-C 3.49Å; E682-A684 VanDerWaalsContact C-N 3.26Å; E682-A684 PolarHBondContact O-N 3.24Å
685L56.6Low52.3Low107 Ų107116.4 Ų116.456%0.5664%0.642SS**Hα-helixtrans-114.6-10.5178.8-73.9169.2000113.1L681 E682 D687L681-L685 HydrophobicContact CB-CD1 4.48Å; L681-L685 HydrophobicContact CD2-CD1 4.37Å; L681-L685 VanDerWaalsContact O-CB 3.23Å; L681-L685 WeakPolarHBondContact O-CB 3.46Å; L681-L685 WeakPolarHBondContact O-CD1 3.19Å; L681-L685 WeakPolarHBondContact O-CG 3.16Å; L681-L685 PolarHBondContact O-N 3.34Å; E682-L685 CarbonylContact O-C 3.5Å; E682-L685 VanDerWaalsContact O-N 3.11Å; E682-L685 PolarHBondContact O-N 3.34Å; L685-D687 PolarHBondContact O-N 3.16Å
686Q54.8Low51Low153 Ų153115 Ų11572%0.71564%0.635SS**SBendtrans-62.6113.7159.2-80.1-178.7-40.900107.5E682 E688E682-Q686 PolarHBondContact O-N 2.92Å; Q686-E688 PolarHBondContact O-N 3.13Å
687D52.8Low49.9Very low123 Ų123112 Ų11266%0.65863%0.633SS**PPolyproline II helixtrans-58.8126.9167.5-61.6-54.5000107.2R571 L685 D689R571-D687 IonicContact NH2-OD1 2.74Å; R571-D687 PolarHBondContact NH2-OD1 3.43Å; L685-D687 PolarHBondContact O-N 3.16Å; D687-D689 PolarHBondContact O-N 2.84Å
688E47.7Very low48.5Very low192 Ų192118 Ų11890%0.89765%0.653SS**PPolyproline II helixtrans-63.3123.5173.8-72.1-170.6171.500108.1Q686Q686-E688 PolarHBondContact O-N 3.13Å
689D41Very low46.9Very low155 Ų155122.5 Ų122.583%0.82967%0.674SS**PPolyproline II helixtrans-51.1141.1-172.5-75.2-57.7000112.5D687 I691D687-D689 PolarHBondContact O-N 2.84Å; D689-I691 PolarHBondContact O-N 3.37Å
690E39.7Very low45.3Very low159 Ų159124.9 Ų124.974%0.74369%0.687SS**  trans-47.2112.7179.7-63.6-177.7156.300112.1Q692E690-Q692 HydrophobicContact CB-CG 4.34Å; E690-Q692 PolarHBondContact OE2-NE2 2.92Å; E690-Q692 PolarHBondContact O-N 3.14Å
691I39.2Very low43.7Very low155 Ų155129.3 Ų129.380%0.79571%0.709SS**  trans-72.488.3160.6-55.9-179.8000107.1D689 V693D689-I691 PolarHBondContact O-N 3.37Å; I691-V693 VanDerWaalsContact C-N 3.33Å; I691-V693 HydrophobicContact CG2-CG2 4.04Å; I691-V693 PolarHBondContact O-N 3.15Å
692Q33.6Very low42.3Very low156 Ų156129.7 Ų129.773%0.72972%0.719SS**  trans-63.496.6166.1-69.6-1722.200108.7E690 D694E690-Q692 HydrophobicContact CB-CG 4.34Å; E690-Q692 PolarHBondContact OE2-NE2 2.92Å; E690-Q692 PolarHBondContact O-N 3.14Å; Q692-D694 PolarHBondContact O-N 3.23Å
693V37Very low40.7Very low115 Ų115132 Ų13270%0.69774%0.735SS**  trans-74.381173.5-171.70000108.4I691 A695I691-V693 VanDerWaalsContact C-N 3.33Å; I691-V693 HydrophobicContact CG2-CG2 4.04Å; I691-V693 PolarHBondContact O-N 3.15Å; V693-A695 PolarHBondContact O-N 3.02Å
694D34.5Very low39Very low117 Ų117138.5 Ų138.563%0.62675%0.751SS**  trans-66.397.9173.6-170.7-19.1000109.7Q692 S696Q692-D694 PolarHBondContact O-N 3.23Å; D694-S696 VanDerWaalsContact CG-OG 3.3Å; D694-S696 PolarHBondContact O-N 2.89Å; D694-S696 WeakPolarHBondContact OD1-CB 3.18Å; D694-S696 PolarHBondContact OD1-N 2.96Å; D694-S696 VanDerWaalsContact OD1-N 3.15Å; D694-S696 PolarHBondContact OD1-OG 3.4Å
695A39.1Very low37.8Very low78 Ų78144.6 Ų144.665%0.64576%0.763SS**G310 helixtrans-80.717.3-17600000113.9V693 T697V693-A695 PolarHBondContact O-N 3.02Å; A695-T697 PolarHBondContact O-N 2.92Å; A695-T697 VanDerWaalsContact O-N 3.1Å
696S38.1Very low36.5Very low83 Ų83145.3 Ų145.358%0.5878%0.777SS**G310 helixtrans-65.9-3.8176.154.50000115D694D694-S696 VanDerWaalsContact CG-OG 3.3Å; D694-S696 PolarHBondContact O-N 2.89Å; D694-S696 WeakPolarHBondContact OD1-CB 3.18Å; D694-S696 PolarHBondContact OD1-N 2.96Å; D694-S696 VanDerWaalsContact OD1-N 3.15Å; D694-S696 PolarHBondContact OD1-OG 3.4Å
697T33.3Very low35.3Very low122 Ų122148 Ų14875%0.74879%0.786SS**G310 helixtrans-90.47.4-176.735.50000115.9A695A695-T697 PolarHBondContact O-N 2.92Å; A695-T697 VanDerWaalsContact O-N 3.1Å
698F32.2Very low34.2Very low205 Ų205148.1 Ų148.190%0.89980%0.797SS**  trans-102.740173.6-95.6-82.9000114.4
699E32.3Very low33.3Very low184 Ų184150.7 Ų150.786%0.8680%0.798SS**  trans-81.6126.8160.2-77.8-150.8144.100111.7
700S32.5Very low33.5Very low104 Ų104148.8 Ų148.873%0.72779%0.794SS**  trans-64.2130.7-173.755.60000113.8S702S700-S702 PolarHBondContact O-N 2.75Å
701T29.3Very low33Very low153 Ų153150.5 Ų150.594%0.93980%0.799SS**  trans-61.9102.616536.90000111.1
702S30.2Very low32.5Very low107 Ų107149.6 Ų149.675%0.74880%0.801SS**  trans-122.6138.3170.167.70000111.8S700 K704S700-S702 PolarHBondContact O-N 2.75Å; S702-K704 PolarHBondContact O-N 3.47Å
703N31.2Very low32.2Very low159 Ų159145.9 Ų145.985%0.8581%0.805SS**  trans-56.7129.9-170.6-88.3-57.7000114.3
704K29.3Very low31.9Very low206 Ų206150.6 Ų150.690%0.89681%0.81SS**  trans-142.6115.5143.7-104.9171.8-165.6175.10111.9S702S702-K704 PolarHBondContact O-N 3.47Å
705K29.2Very low31.8Very low203 Ų203153.5 Ų153.588%0.88382%0.817SS**  trans-78.3128.9168.1-74.7172.7174170.80109.9
706S29Very low31.3Very low122 Ų122155.4 Ų155.485%0.85383%0.825SS**  trans-155.7143.2148.5490000111.9
707K30.2Very low30.8Very low210 Ų210155.4 Ų155.491%0.91384%0.838SS**  trans-86.7142-172.2-57.6161.1176.1172.10111.7
708S29.3Very low30.6Very low125 Ų125152.8 Ų152.887%0.87484%0.836SS**  trans-161.2139142.149.90000112.2
709R30Very low30.4Very low246 Ų246148.8 Ų148.893%0.92883%0.834SS**  trans-90.7164.7179.9-94.7174.290.6177.66.9112
710P43.4Very low30.4Very low115 Ų115144.8 Ų144.875%0.74783%0.826SS**  trans-93.2166.3-165.237.8-38000114.5
711K29.7Very low30.3Very low195 Ų195145.2 Ų145.285%0.84883%0.829SS**  trans-159.7111.3158.5-97173.6-176.4-179.30108
712T28.5Very low30.3Very low137 Ų137142.9 Ų142.984%0.8483%0.825SS**  82120.473.359.70000116.5
713G29Very low30.2Very low77 Ų77141.5 Ų141.579%0.79483%0.828SS**  trans122142.9149.100000115.4
714R30.7Very low30.2Very low214 Ų214139.8 Ų139.881%0.80882%0.823SS**  cis173127.6-21.2-132-167.6173-176.3-0.6107.1
715K31.3Very low30.3Very low179 Ų179138 Ų13878%0.77882%0.818SS**  trans62.6159.7153.7-64.2-174.4171.1-165.30117.8
716S29.6Very low30.4Very low117 Ų117133 Ų13382%0.81881%0.808SS**  cis-165.7169.9-2.725.90000108.9
717G27.6Very low30.5Very low83 Ų83132.3 Ų132.386%0.85680%0.803SS**  cis145.3127.5-4.200000114
718G28.5Very low30.8Very low67 Ų67131.4 Ų131.469%0.69180%0.802SS**  trans144.3117.1179.800000110.9
719S28.7Very low31Very low122 Ų122133.5 Ų133.585%0.85380%0.803SS**  70.6130.870.970.70000113.2
720S30.4Very low31.4Very low100 Ų100132.6 Ų132.670%0.69980%0.801SS**  cis-166.2159.729.850.70000115.1
721S30.7Very low31.3Very low112 Ų112133 Ų13378%0.78380%0.804SS**  trans55.2150.1147.459.20000122
722A30.6Very low31.4Very low105 Ų105133 Ų13387%0.86881%0.807SS**  cis-172.5152.2-19.800000108.2
723G28Very low32.1Very low78 Ų78131.8 Ų131.880%0.80480%0.804SS**  trans168.993.6176.900000116.7
724T30.6Very low32.4Very low123 Ų123140.3 Ų140.376%0.75581%0.812SS**  trans-35.8136.3172.639.80000119.2
725H31.2Very low32.5Very low169 Ų169133.4 Ų133.478%0.78281%0.807SS**  -172146.3100.9-103.2-76.2000115.8
726S31.2Very low32.8Very low96 Ų96132.7 Ų132.767%0.67181%0.811SS**  trans-29160.3162.147.10000119.2
727S31.5Very low33.2Very low109 Ų109133.1 Ų133.176%0.76281%0.808SS**  cis-176.5144-11.848.70000109.1
728Q36.3Very low34.2Very low190 Ų190134.4 Ų134.489%0.88880%0.802SS**  trans-77.7143.6174.9-69.7176.1-34.100112.8
729L34Very low34.7Very low170 Ų170144.5 Ų144.589%0.8983%0.827SS**  trans-166.8120.5151.9-106.1145000111.5
730Y38.3Very low35Very low226 Ų226145.7 Ų145.789%0.88683%0.825SS**  trans-78.8158.2162.7-78.1-92.7000110.3
731P40.5Very low35.3Very low124 Ų124148.1 Ų148.181%0.80583%0.832SS**  trans-128.5160.9141.535-24.2000114.1
732Q32.2Very low35.5Very low195 Ų195150.1 Ų150.191%0.91184%0.835SS**  trans-89.9173.6-174.2-68.4177.2-45.200114.4
733S43.1Very low35.8Very low111 Ų111152.7 Ų152.778%0.77683%0.833SS**  trans-62.5145.4178.154.40000117.6
734R34.8Very low36.3Very low257 Ų257157.4 Ų157.497%0.9784%0.835SS**  trans-170.3151.8145.3-98.2166.3-174.7-161.80.8106.5
735G34.6Very low36.7Very low68 Ų68159.7 Ų159.770%0.70184%0.84SS**  cis145.689.91.600000111.7
736L36.1Very low37.1Very low164 Ų164159 Ų15986%0.85984%0.844SS**  trans60.3120.2157.5-62.5165.9000122.4
737V38.2Very low37.6Very low126 Ų126163.8 Ų163.876%0.76486%0.857SS**  60.9153.1121.7-173.20000119.6
738P48.8Very low38.1Very low111 Ų111168.4 Ų168.472%0.72187%0.865SS**  cis-124.8179.8-36.337.4-21.6000113.5
739K39.9Very low38.2Very low279 Ų279166.5 Ų166.5100%1.21386%0.863SS**  -151.20124.5-117.8-176.6-175.1-177.70111

Retrieved 739 of 739 residues in 137.7 ms (Link to these results)