A0A093JQN3_STRCA Loading...

Asparagine synthetase [glutamine-hydrolyzing]

AlphaFold DB , UniProt , Accession A0A093JQN3, Species STRCA (Struthio camelus australis), Gene n/a, Length 561 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M87.3Confident95.2Very high0 Ų09.4 Ų9.40%05%0.053CC..  0156.70-77.5-173.9-91.100108.2R27 G28 R143 D406 T409 A410 L414 E415 L416M1-R27 CarbonylContact C-O 3.52Å; M1-R27 PolarHBondContact N-O 3.18Å; M1-R27 CarbonylContact O-C 3.59Å; M1-R27 WeakPolarHBondContact O-CA 3.36Å; M1-R27 WeakPolarHBondContact O-CB 3.29Å; M1-G28 PolarHBondContact O-N 3.23Å; M1-R143 PolarHBondContact SD-NH1 3.19Å; M1-D406 HydrophobicContact CE-CB 3.92Å; M1-D406 WeakPolarHBondContact CE-O 3.31Å; M1-D406 WeakPolarHBondContact CE-OD1 3.24Å; M1-T409 VanDerWaalsContact CE-OG1 3.23Å; M1-T409 WeakPolarHBondContact CE-OG1 3.1Å; M1-A410 HydrophobicContact CB-CB 4.3Å; M1-A410 HydrophobicContact CE-CB 3.78Å; M1-L414 WeakPolarHBondContact CG-O 3.42Å; M1-L414 PolarHBondContact N-O 2.86Å; M1-E415 HydrophobicContact CG-CB 4.14Å; M1-E415 HydrophobicContact CG-CG 4.05Å; M1-L416 HydrophobicContact CE-CB 3.94Å; M1-L416 HydrophobicContact SD-CB 4.35Å
2C97.8Very high93.9Very high14 Ų1415.9 Ų15.910%0.0958%0.082CC..  trans-72.7159.5179.1-630000112.2R27 F47 H48 L50 N75C2-R27 PolarHBondContact O-NE 3.33Å; C2-R27 VanDerWaalsContact O-NE 3.1Å; C2-F47 HydrophobicContact CB-CE2 3.57Å; C2-F47 HydrophobicContact CB-CZ 3.47Å; C2-F47 VanDerWaalsContact CB-CZ 3.47Å; C2-F47 VanDerWaalsContact SG-CZ 3.53Å; C2-H48 CarbonylContact C-O 3.38Å; C2-H48 WeakPolarHBondContact CA-O 3.47Å; C2-H48 WeakPolarHBondContact CB-O 3.44Å; C2-L50 PolarHBondContact SG-N 2.99Å; C2-L50 VanDerWaalsContact SG-N 3.36Å; C2-L50 PolarHBondContact SG-O 2.75Å; C2-N75 HydrophobicContact CB-CB 4.14Å; C2-N75 PolarHBondContact N-OD1 3.04Å; C2-N75 PolarHBondContact O-ND2 2.91Å; C2-N75 PolarHBondContact O-OD1 3.25Å
3G98.6Very high92.6Very high0 Ų020.3 Ų20.30%011%0.114CC..EExtended strand (participates in β ladder)trans-112116.4169.300000109.6F47 H48G3-F47 WeakPolarHBondContact O-CA 3.37Å; G3-H48 PolarHBondContact N-O 3.28Å; G3-H48 PolarHBondContact O-N 3.47Å
4I98.8Very high91.7Very high0 Ų020.5 Ų20.50%012%0.115CC..EExtended strand (participates in β ladder)trans-100.3138.5173.161.7171.3000110I24 F47 C73 N75 A122 I124 L145 C158 S159I4-I24 WeakPolarHBondContact O-CD1 3.41Å; I4-F47 HydrophobicContact CG2-CD2 3.79Å; I4-F47 HydrophobicContact CG2-CE2 3.75Å; I4-C73 HydrophobicContact CB-CB 4.42Å; I4-C73 HydrophobicContact CG2-CB 4.04Å; I4-N75 HydrophobicContact CG2-CB 4.18Å; I4-A122 HydrophobicContact CD1-CB 4.27Å; I4-A122 WeakPolarHBondContact CD1-O 3.48Å; I4-I124 HydrophobicContact CD1-CD1 3.97Å; I4-I124 HydrophobicContact CD1-CG1 4.09Å; I4-I124 HydrophobicContact CG1-CD1 4.43Å; I4-L145 HydrophobicContact CD1-CD1 3.66Å; I4-L145 HydrophobicContact CG1-CD1 4.24Å; I4-C158 CarbonylContact O-C 3.59Å; I4-C158 VanDerWaalsContact O-CA 3.28Å; I4-C158 WeakPolarHBondContact O-CA 2.96Å; I4-S159 VanDerWaalsContact CG1-OG 3.3Å; I4-S159 WeakPolarHBondContact CG1-OG 3.47Å; I4-S159 PolarHBondContact N-OG 3.48Å; I4-S159 PolarHBondContact O-N 2.97Å
5W98.6Very high90.6Very high0 Ų025.1 Ų25.10%015%0.149CC..EExtended strand (participates in β ladder)trans-145.3136.8173.5-178.697.1000108.8L7 Q17 A21 I24 F34 C44 F45 G46 V157 G163 L167W5-L7 HydrophobicContact CH2-CB 4.42Å; W5-L7 HydrophobicContact CH2-CD1 3.26Å; W5-L7 HydrophobicContact CH2-CD2 4.23Å; W5-L7 HydrophobicContact CH2-CG 3.34Å; W5-L7 HydrophobicContact CZ2-CD1 3.46Å; W5-L7 VanDerWaalsContact CZ2-CD1 3.46Å; W5-L7 HydrophobicContact CZ2-CD2 3.85Å; W5-L7 HydrophobicContact CZ2-CG 3.47Å; W5-L7 VanDerWaalsContact CZ2-CG 3.47Å; W5-L7 HydrophobicContact CZ3-CD1 4.2Å; W5-L7 HydrophobicContact CZ3-CG 3.89Å; W5-Q17 HydrophobicContact CH2-CB 4.19Å; W5-Q17 HydrophobicContact CZ2-CB 4.29Å; W5-Q17 WeakPolarHBondContact CZ2-O 3.28Å; W5-A21 HydrophobicContact CB-CB 4.19Å; W5-A21 HydrophobicContact CD2-CB 3.69Å; W5-A21 HydrophobicContact CE3-CB 3.89Å; W5-A21 HydrophobicContact CG-CB 3.86Å; W5-A21 HydrophobicContact CZ3-CB 4.43Å; W5-I24 HydrophobicContact CB-CD1 4.1Å; W5-F34 HydrophobicContact CH2-CE2 4.31Å; W5-F34 AromaticContact CZ3-CE2 3.72Å; W5-F34 HydrophobicContact CZ3-CE2 3.72Å; W5-C44 VanDerWaalsContact CZ3-SG 3.55Å; W5-F45 WeakPolarHBondContact O-CA 3.33Å; W5-G46 PolarHBondContact N-O 2.73Å; W5-G46 PolarHBondContact O-N 2.8Å; W5-V157 CarbonylContact C-O 3.57Å; W5-V157 VanDerWaalsContact CA-O 3.28Å; W5-V157 WeakPolarHBondContact CA-O 3.49Å; W5-G163 PolarHBondContact NE1-O 3.39Å; W5-G163 VanDerWaalsContact NE1-O 3.1Å; W5-L167 HydrophobicContact CZ2-CD2 4.03Å
6A98.1Very high89.9Confident0 Ų029.2 Ų29.20%017%0.174CC..EExtended strand (participates in β ladder)trans-151.4151.2174.500000111.5F8 C44 F45 I124 G156 V157A6-F8 HydrophobicContact CB-CE2 3.92Å; A6-F8 HydrophobicContact CB-CZ 4.46Å; A6-C44 CarbonylContact C-O 3.53Å; A6-C44 WeakPolarHBondContact CA-O 3.39Å; A6-C44 WeakPolarHBondContact CB-O 3.13Å; A6-F45 HydrophobicContact CB-CD1 3.67Å; A6-F45 HydrophobicContact CB-CE1 3.93Å; A6-F45 HydrophobicContact CB-CG 4.31Å; A6-I124 HydrophobicContact CB-CD1 3.72Å; A6-I124 HydrophobicContact CB-CG2 4.39Å; A6-G156 WeakPolarHBondContact O-CA 3.36Å; A6-V157 PolarHBondContact N-O 3Å; A6-V157 PolarHBondContact O-N 2.87Å
7L97.5Very high89.5Confident0 Ų028.1 Ų28.10%017%0.166CC..EExtended strand (participates in β ladder)trans-125.7145.6172-59.9-177.4000110.4W5 Q17 C43 C44 F154 L155 L167W5-L7 HydrophobicContact CH2-CB 4.42Å; W5-L7 HydrophobicContact CH2-CD1 3.26Å; W5-L7 HydrophobicContact CH2-CD2 4.23Å; W5-L7 HydrophobicContact CH2-CG 3.34Å; W5-L7 HydrophobicContact CZ2-CD1 3.46Å; W5-L7 VanDerWaalsContact CZ2-CD1 3.46Å; W5-L7 HydrophobicContact CZ2-CD2 3.85Å; W5-L7 HydrophobicContact CZ2-CG 3.47Å; W5-L7 VanDerWaalsContact CZ2-CG 3.47Å; W5-L7 HydrophobicContact CZ3-CD1 4.2Å; W5-L7 HydrophobicContact CZ3-CG 3.89Å; L7-Q17 HydrophobicContact CD1-CB 3.85Å; L7-Q17 VanDerWaalsContact CD1-CD 3.48Å; L7-Q17 HydrophobicContact CD1-CG 4.2Å; L7-C43 CarbonylContact O-C 3.55Å; L7-C43 WeakPolarHBondContact O-CA 3.35Å; L7-C44 PolarHBondContact N-O 3.14Å; L7-C44 PolarHBondContact O-N 3.26Å; L7-F154 HydrophobicContact CB-CE2 4.31Å; L7-F154 HydrophobicContact CD1-CE2 4.28Å; L7-F154 HydrophobicContact CD1-CZ 4.4Å; L7-F154 HydrophobicContact CD2-CE2 4.01Å; L7-F154 HydrophobicContact CD2-CZ 3.76Å; L7-F154 HydrophobicContact CG-CE2 4.44Å; L7-L155 CarbonylContact C-O 3.41Å; L7-L155 VanDerWaalsContact CA-O 3.32Å; L7-L155 WeakPolarHBondContact CA-O 3.47Å; L7-L167 HydrophobicContact CD1-CD2 4.39Å; L7-L167 HydrophobicContact CD2-CD1 3.74Å; L7-L167 HydrophobicContact CD2-CD2 4.27Å
8F97.6Very high89.1Confident0 Ų027.6 Ų27.60%016%0.164CC..EExtended strand (participates in β ladder)trans-130.7126.4171.6-57.6-97.7000109.6A6 C43 F45 I124 L126 V133 L155 L190 G194 V196A6-F8 HydrophobicContact CB-CE2 3.92Å; A6-F8 HydrophobicContact CB-CZ 4.46Å; F8-C43 HydrophobicContact CD1-CB 4.04Å; F8-F45 HydrophobicContact CE1-CZ 4.27Å; F8-F45 HydrophobicContact CZ-CE1 4.23Å; F8-F45 AromaticContact CZ-CZ 3.8Å; F8-F45 HydrophobicContact CZ-CZ 3.8Å; F8-I124 HydrophobicContact CE2-CG2 3.95Å; F8-I124 HydrophobicContact CZ-CG2 3.87Å; F8-L126 HydrophobicContact CE1-CB 4.26Å; F8-L126 HydrophobicContact CE1-CD1 4.25Å; F8-L126 HydrophobicContact CE1-CD2 4.26Å; F8-L126 HydrophobicContact CE1-CG 4.49Å; F8-V133 HydrophobicContact CD1-CG2 3.67Å; F8-V133 HydrophobicContact CD2-CG1 4.47Å; F8-V133 HydrophobicContact CE1-CB 4.45Å; F8-V133 HydrophobicContact CE1-CG1 4.06Å; F8-V133 HydrophobicContact CE1-CG2 3.48Å; F8-V133 VanDerWaalsContact CE1-CG2 3.48Å; F8-V133 HydrophobicContact CE2-CG1 3.89Å; F8-V133 HydrophobicContact CG-CG2 4.34Å; F8-V133 HydrophobicContact CZ-CG1 3.66Å; F8-V133 HydrophobicContact CZ-CG2 4Å; F8-L155 HydrophobicContact CB-CB 4.26Å; F8-L155 HydrophobicContact CD2-CB 4.38Å; F8-L155 HydrophobicContact CD2-CD2 3.67Å; F8-L155 HydrophobicContact CD2-CG 4.21Å; F8-L155 HydrophobicContact CE2-CD2 4.15Å; F8-L155 HydrophobicContact CG-CD2 4.4Å; F8-L155 PolarHBondContact N-O 2.8Å; F8-L155 PolarHBondContact O-N 3.01Å; F8-L190 HydrophobicContact CD1-CD1 4.44Å; F8-G194 CarbonylContact C-O 3.34Å; F8-V196 HydrophobicContact CB-CG1 3.83Å; F8-V196 HydrophobicContact CG-CG1 4.3Å
9G95.4Very high89.1Confident0 Ų032.8 Ų32.80%019%0.191CC..SBendtrans73.239.6176.500000113.4N42 G194 K195G9-N42 PolarHBondContact N-O 3.21Å; G9-G194 VanDerWaalsContact CA-C 3.48Å; G9-G194 WeakPolarHBondContact CA-O 3.49Å; G9-G194 PolarHBondContact N-O 3.46Å; G9-K195 WeakPolarHBondContact O-CD 3.24Å; G9-K195 WeakPolarHBondContact O-CE 3.49Å; G9-K195 PolarHBondContact O-NZ 2.92Å
10S92.1Very high89Confident5 Ų531.6 Ų31.64%0.03518%0.184CC..  trans-70.4138174.6-173.40000111.5E12 Q17 N42S10-E12 PolarHBondContact OG-N 3.31Å; S10-Q17 PolarHBondContact OG-NE2 3.16Å; S10-Q17 PolarHBondContact OG-OE1 2.64Å; S10-N42 PolarHBondContact N-O 3.36Å; S10-N42 VanDerWaalsContact N-O 3.09Å; S10-N42 VanDerWaalsContact O-CB 3.25Å; S10-N42 WeakPolarHBondContact O-CB 3.2Å
11D85.8Confident89.1Confident84 Ų8430.1 Ų30.145%0.44918%0.175SC..  trans-94-7172.9-58.5-16.9000112H169 S170 K195D11-H169 IonicContact OD2-CE1 3.64Å; D11-H169 PolarHBondContact OD2-CE1 3.03Å; D11-H169 IonicContact OD2-ND1 3.9Å; D11-H169 IonicContact OD2-NE2 3.96Å; D11-S170 PolarHBondContact OD2-OG 2.98Å; D11-K195 WeakPolarHBondContact OD1-CE 3.49Å; D11-K195 IonicContact OD1-NZ 3.6Å; D11-K195 PolarHBondContact OD1-NZ 2.85Å; D11-K195 IonicContact OD2-NZ 2.82Å; D11-K195 PolarHBondContact OD2-NZ 3.43Å
12E79.5Confident89.5Confident88 Ų8833.8 Ų33.841%0.41119%0.194SC..SBendtrans-100.2166.5-173.6-72.8-67.2161.700112.4S10 L14 Q17S10-E12 PolarHBondContact OG-N 3.31Å; E12-L14 PolarHBondContact O-N 3.27Å; E12-Q17 HydrophobicContact CB-CG 4.36Å
13C76.4Confident89.4Confident73 Ų7336.3 Ų36.349%0.49320%0.203SC..  trans-62.3113.6170.9-1790000110.2S15 V16 Q17C13-S15 PolarHBondContact O-N 2.95Å; C13-V16 HydrophobicContact CB-CB 4.5Å; C13-V16 HydrophobicContact CB-CG2 3.98Å; C13-V16 WeakPolarHBondContact O-CB 3.06Å; C13-V16 PolarHBondContact O-N 3.26Å; C13-Q17 PolarHBondContact O-N 2.89Å
14L80.5Confident89.4Confident23 Ų2336.3 Ų36.312%0.1220%0.203CC..Hα-helixtrans-54.7-30.3178.6-69.8-171.6000113.3E12 V16 Q17 C18 F34 N36 T41 C44E12-L14 PolarHBondContact O-N 3.27Å; L14-V16 VanDerWaalsContact C-N 3.28Å; L14-V16 PolarHBondContact O-N 3.37Å; L14-Q17 PolarHBondContact O-N 3.43Å; L14-C18 WeakPolarHBondContact O-CB 3.09Å; L14-C18 PolarHBondContact O-N 3.47Å; L14-F34 HydrophobicContact CB-CZ 4.15Å; L14-N36 HydrophobicContact CD1-CB 3.93Å; L14-T41 WeakPolarHBondContact CD1-O 3.37Å; L14-C44 HydrophobicContact CD1-CB 3.85Å
15S74.9Confident89.3Confident90 Ų9038 Ų3863%0.62922%0.217SC*.Hα-helixtrans-63.7-33175.6-172.20000112.8C13C13-S15 PolarHBondContact O-N 2.95Å
16V80.1Confident89.3Confident90 Ų9040.5 Ų40.555%0.54523%0.228SC..Hα-helixtrans-73.2-43177.1177.30000109.6C13 L14 C18 L19C13-V16 HydrophobicContact CB-CB 4.5Å; C13-V16 HydrophobicContact CB-CG2 3.98Å; C13-V16 WeakPolarHBondContact O-CB 3.06Å; C13-V16 PolarHBondContact O-N 3.26Å; L14-V16 VanDerWaalsContact C-N 3.28Å; L14-V16 PolarHBondContact O-N 3.37Å; V16-C18 VanDerWaalsContact C-N 3.29Å; V16-C18 PolarHBondContact O-N 2.69Å; V16-L19 WeakPolarHBondContact O-CB 3.13Å; V16-L19 PolarHBondContact O-N 3.04Å
17Q82.4Confident89.4Confident10 Ų1040.5 Ų40.55%0.04723%0.228CC..Hα-helixtrans-71.3-22.7179-69.5175.1-27.300113.2W5 L7 S10 E12 C13 L14 L19 S20 L167 K168W5-Q17 HydrophobicContact CH2-CB 4.19Å; W5-Q17 HydrophobicContact CZ2-CB 4.29Å; W5-Q17 WeakPolarHBondContact CZ2-O 3.28Å; L7-Q17 HydrophobicContact CD1-CB 3.85Å; L7-Q17 VanDerWaalsContact CD1-CD 3.48Å; L7-Q17 HydrophobicContact CD1-CG 4.2Å; S10-Q17 PolarHBondContact OG-NE2 3.16Å; S10-Q17 PolarHBondContact OG-OE1 2.64Å; E12-Q17 HydrophobicContact CB-CG 4.36Å; C13-Q17 PolarHBondContact O-N 2.89Å; L14-Q17 PolarHBondContact O-N 3.43Å; Q17-L19 PolarHBondContact O-N 3.21Å; Q17-S20 WeakPolarHBondContact O-CA 3.45Å; Q17-S20 WeakPolarHBondContact O-CB 3.33Å; Q17-S20 PolarHBondContact O-N 3.49Å; Q17-L167 HydrophobicContact CB-CD2 4.41Å; Q17-L167 HydrophobicContact CG-CD2 4.36Å; Q17-K168 PolarHBondContact NE2-O 3.22Å
18C83.1Confident89.4Confident20 Ų2040.5 Ų40.514%0.13523%0.229CC..Hα-helixtrans-57.4-28.8172.9-174.90000112.7L14 V16 S20 A21 M22 F34L14-C18 WeakPolarHBondContact O-CB 3.09Å; L14-C18 PolarHBondContact O-N 3.47Å; V16-C18 VanDerWaalsContact C-N 3.29Å; V16-C18 PolarHBondContact O-N 2.69Å; C18-S20 PolarHBondContact O-N 3.01Å; C18-A21 WeakPolarHBondContact O-CB 3.22Å; C18-A21 PolarHBondContact O-N 2.99Å; C18-M22 PolarHBondContact O-N 3.16Å; C18-F34 HydrophobicContact CB-CD2 4.18Å; C18-F34 HydrophobicContact CB-CE2 3.83Å; C18-F34 HydrophobicContact CB-CZ 4.09Å; C18-F34 VanDerWaalsContact SG-CD2 3.6Å
19L87.8Confident89.4Confident127 Ų12743 Ų4367%0.66524%0.244SC*.Hα-helixtrans-60.1-32.1172.7-64.8175.2000112.1V16 Q17 A21 M22V16-L19 WeakPolarHBondContact O-CB 3.13Å; V16-L19 PolarHBondContact O-N 3.04Å; Q17-L19 PolarHBondContact O-N 3.21Å; L19-A21 VanDerWaalsContact C-N 3.34Å; L19-M22 WeakPolarHBondContact O-CB 3.36Å; L19-M22 PolarHBondContact O-N 3.32Å
20S88.4Confident89.5Confident8 Ų846.4 Ų46.46%0.05626%0.263CS..Hα-helixtrans-67.7-35.7175.6-149.20000111.8Q17 C18 M22 K23 G163Q17-S20 WeakPolarHBondContact O-CA 3.45Å; Q17-S20 WeakPolarHBondContact O-CB 3.33Å; Q17-S20 PolarHBondContact O-N 3.49Å; C18-S20 PolarHBondContact O-N 3.01Å; S20-M22 PolarHBondContact O-N 3.38Å; S20-K23 WeakPolarHBondContact O-CB 3.39Å; S20-K23 PolarHBondContact O-N 3.4Å; S20-G163 PolarHBondContact OG-O 2.84Å
21A90.5Very high89.8Confident0 Ų048.2 Ų48.20%028%0.278CS..Hα-helixtrans-63.9-26.5174.100000112.1W5 C18 L19 K23 I24 H48W5-A21 HydrophobicContact CB-CB 4.19Å; W5-A21 HydrophobicContact CD2-CB 3.69Å; W5-A21 HydrophobicContact CE3-CB 3.89Å; W5-A21 HydrophobicContact CG-CB 3.86Å; W5-A21 HydrophobicContact CZ3-CB 4.43Å; C18-A21 WeakPolarHBondContact O-CB 3.22Å; C18-A21 PolarHBondContact O-N 2.99Å; L19-A21 VanDerWaalsContact C-N 3.34Å; A21-K23 VanDerWaalsContact C-N 3.29Å; A21-K23 PolarHBondContact O-N 2.63Å; A21-I24 VanDerWaalsContact O-CG1 3.24Å; A21-I24 WeakPolarHBondContact O-CG1 3.43Å; A21-H48 PolarHBondContact O-CD2 3.07Å; A21-H48 VanDerWaalsContact O-CD2 3.32Å; A21-H48 PolarHBondContact O-NE2 3.48Å
22M95.6Very high90.4Very high78 Ų7847.7 Ų47.738%0.38427%0.272SS..Hα-helixtrans-72.6-20179.2-59.8-60.2168.100113.6C18 L19 S20 I24 A25 F32C18-M22 PolarHBondContact O-N 3.16Å; L19-M22 WeakPolarHBondContact O-CB 3.36Å; L19-M22 PolarHBondContact O-N 3.32Å; S20-M22 PolarHBondContact O-N 3.38Å; M22-I24 PolarHBondContact O-N 2.92Å; M22-I24 VanDerWaalsContact O-N 3.11Å; M22-A25 VanDerWaalsContact O-CB 3.24Å; M22-A25 WeakPolarHBondContact O-CB 3.44Å; M22-A25 PolarHBondContact O-N 3.17Å; M22-A25 VanDerWaalsContact O-N 3.11Å; M22-F32 HydrophobicContact CE-CD1 3.74Å; M22-F32 HydrophobicContact CE-CE1 3.16Å; M22-F32 HydrophobicContact CE-CE2 4.16Å; M22-F32 HydrophobicContact CE-CG 4.43Å; M22-F32 HydrophobicContact CE-CZ 3.38Å; M22-F32 HydrophobicContact SD-CD1 4.49Å; M22-F32 HydrophobicContact SD-CE1 4.28Å; M22-F32 HydrophobicContact SD-CE2 4.47Å; M22-F32 HydrophobicContact SD-CZ 4.24Å
23K95.6Very high91.3Very high67 Ų6747.9 Ų47.929%0.29127%0.269SS..THydrogen-bonded Turntrans-65.4-13.8179.6-68.2-174.8168.9-1610114.3S20 A21 H26 K162 D166S20-K23 WeakPolarHBondContact O-CB 3.39Å; S20-K23 PolarHBondContact O-N 3.4Å; A21-K23 VanDerWaalsContact C-N 3.29Å; A21-K23 PolarHBondContact O-N 2.63Å; K23-H26 PolarHBondContact O-CE1 3.2Å; K23-H26 PolarHBondContact O-ND1 3.46Å; K23-K162 WeakPolarHBondContact CD-O 3.36Å; K23-K162 PolarHBondContact NZ-O 3.14Å; K23-D166 WeakPolarHBondContact CE-OD2 3.46Å; K23-D166 IonicContact NZ-OD1 2.89Å; K23-D166 PolarHBondContact NZ-OD1 3.01Å; K23-D166 IonicContact NZ-OD2 3.8Å; K23-D166 PolarHBondContact NZ-OD2 2.98Å
24I98.1Very high92.3Very high0 Ų047.4 Ų47.40%026%0.259CS..THydrogen-bonded Turntrans-110.514.2177.961.8163.3000113I4 W5 A21 M22 H26 R27 E160 K162I4-I24 WeakPolarHBondContact O-CD1 3.41Å; W5-I24 HydrophobicContact CB-CD1 4.1Å; A21-I24 VanDerWaalsContact O-CG1 3.24Å; A21-I24 WeakPolarHBondContact O-CG1 3.43Å; M22-I24 PolarHBondContact O-N 2.92Å; M22-I24 VanDerWaalsContact O-N 3.11Å; I24-H26 PolarHBondContact O-N 2.9Å; I24-R27 WeakPolarHBondContact O-CB 3.48Å; I24-R27 WeakPolarHBondContact O-CG 3.44Å; I24-R27 PolarHBondContact O-N 2.78Å; I24-E160 HydrophobicContact CG2-CB 3.89Å; I24-E160 HydrophobicContact CG2-CG 4.37Å; I24-K162 HydrophobicContact CG2-CG 4.32Å
25A98.4Very high93Very high35 Ų3548.3 Ų48.329%0.28926%0.262SS..THydrogen-bonded Turntrans-61.2-29.8-177.700000113.4M22 R27 G28M22-A25 VanDerWaalsContact O-CB 3.24Å; M22-A25 WeakPolarHBondContact O-CB 3.44Å; M22-A25 PolarHBondContact O-N 3.17Å; M22-A25 VanDerWaalsContact O-N 3.11Å; A25-R27 PolarHBondContact O-N 3.27Å; A25-R27 VanDerWaalsContact O-N 3.16Å; A25-G28 CarbonylContact O-C 3.46Å; A25-G28 PolarHBondContact O-N 3.2Å
26H98.5Very high94Very high52 Ų5247.3 Ų47.324%0.24125%0.25CC..THydrogen-bonded Turntrans-55.5-32.5177.852.6-86.6000113.2K23 I24 E160 A410 G413K23-H26 PolarHBondContact O-CE1 3.2Å; K23-H26 PolarHBondContact O-ND1 3.46Å; I24-H26 PolarHBondContact O-N 2.9Å; H26-E160 IonicContact CD2-OE1 3.32Å; H26-E160 IonicContact CE1-OE2 3.55Å; H26-E160 PolarHBondContact CE1-OE2 3.34Å; H26-E160 VanDerWaalsContact NE2-CD 3.34Å; H26-E160 IonicContact NE2-OE1 3.77Å; H26-E160 PolarHBondContact NE2-OE1 3.26Å; H26-E160 IonicContact NE2-OE2 3.34Å; H26-E160 PolarHBondContact NE2-OE2 2.71Å; H26-A410 CarbonylContact C-O 3.51Å; H26-A410 VanDerWaalsContact O-O 3.06Å; H26-G413 VanDerWaalsContact O-CA 3.31Å; H26-G413 WeakPolarHBondContact O-CA 3.27Å; H26-G413 PolarHBondContact O-N 2.94Å
27R98.7Very high94.7Very high0 Ų043.1 Ų43.10%022%0.224CC..THydrogen-bonded Turntrans-62.1-53.1179.2-54-172.964.984-0.6109.8M1 C2 I24 A25 P29 N75 E160 D406 A410 G413M1-R27 CarbonylContact C-O 3.52Å; M1-R27 PolarHBondContact N-O 3.18Å; M1-R27 CarbonylContact O-C 3.59Å; M1-R27 WeakPolarHBondContact O-CA 3.36Å; M1-R27 WeakPolarHBondContact O-CB 3.29Å; C2-R27 PolarHBondContact O-NE 3.33Å; C2-R27 VanDerWaalsContact O-NE 3.1Å; I24-R27 WeakPolarHBondContact O-CB 3.48Å; I24-R27 WeakPolarHBondContact O-CG 3.44Å; I24-R27 PolarHBondContact O-N 2.78Å; A25-R27 PolarHBondContact O-N 3.27Å; A25-R27 VanDerWaalsContact O-N 3.16Å; R27-P29 WeakPolarHBondContact O-CD 3.34Å; R27-N75 PolarHBondContact NH2-ND2 2.65Å; R27-N75 VanDerWaalsContact NH2-ND2 3.2Å; R27-E160 VanDerWaalsContact CD-OE1 3.26Å; R27-E160 WeakPolarHBondContact CD-OE1 3.46Å; R27-E160 IonicContact CZ-OE1 2.68Å; R27-E160 IonicContact NE-OE1 2.77Å; R27-E160 IonicContact NH1-OE1 3.94Å; R27-E160 PolarHBondContact NH1-OE1 3.32Å; R27-D406 IonicContact CZ-OD1 3Å; R27-D406 IonicContact CZ-OD2 3.14Å; R27-D406 IonicContact NH1-OD1 3.11Å; R27-D406 IonicContact NH1-OD2 2.74Å; R27-D406 PolarHBondContact NH1-OD2 2.98Å; R27-D406 IonicContact NH2-OD1 3.81Å; R27-D406 PolarHBondContact NH2-OD1 2.96Å; R27-D406 IonicContact NH2-OD2 3.18Å; R27-D406 PolarHBondContact NH2-OD2 3.25Å; R27-D406 VanDerWaalsContact NH2-OD2 3.14Å; R27-A410 WeakPolarHBondContact CA-O 3.37Å; R27-A410 HydrophobicContact CB-CB 4.42Å; R27-A410 HydrophobicContact CG-CB 4.06Å; R27-A410 VanDerWaalsContact NH1-CB 3.26Å; R27-G413 WeakPolarHBondContact O-CA 3.47Å
28G98.4Very high95.2Very high1 Ų147.9 Ų47.91%0.0125%0.25CC..  trans-117.978.5-171.200000113.4M1 A25 D30 R49M1-G28 PolarHBondContact O-N 3.23Å; A25-G28 CarbonylContact O-C 3.46Å; A25-G28 PolarHBondContact O-N 3.2Å; G28-D30 VanDerWaalsContact C-N 3.32Å; G28-D30 PolarHBondContact O-N 3.09Å; G28-R49 CarbonylContact C-O 3.58Å; G28-R49 VanDerWaalsContact CA-O 3.31Å; G28-R49 WeakPolarHBondContact CA-O 3.43Å; G28-R49 PolarHBondContact O-N 2.92Å
29P97.7Very high95.6Very high51 Ų5158.5 Ų58.533%0.33129%0.287SS..  trans-77.4-9.2-171.333.4-40.1000115.2R27 L50R27-P29 WeakPolarHBondContact O-CD 3.34Å; P29-L50 HydrophobicContact CG-CD1 4.16Å
30D98.1Very high95.9Very high73 Ų7353.6 Ų53.639%0.3926%0.261SS..SBendtrans-84.2-35.7-168.2-61.6-19.6000112.2G28 R49 S51 R251G28-D30 VanDerWaalsContact C-N 3.32Å; G28-D30 PolarHBondContact O-N 3.09Å; D30-R49 WeakPolarHBondContact CA-O 3.29Å; D30-R49 VanDerWaalsContact CB-O 3.31Å; D30-R49 WeakPolarHBondContact CB-O 3.39Å; D30-R49 PolarHBondContact N-O 3.14Å; D30-S51 PolarHBondContact OD2-N 3.4Å; D30-R251 IonicContact OD2-NH1 3.89Å; D30-R251 PolarHBondContact OD2-NH1 2.99Å
31A98.1Very high96.2Very high42 Ų4257.7 Ų57.735%0.34729%0.286SS..EExtended strand (participates in β ladder)trans-160155.4178.600000112.2H48 R49 M59A31-H48 WeakPolarHBondContact O-CA 3.45Å; A31-R49 HydrophobicContact CB-CB 4.32Å; A31-R49 PolarHBondContact N-O 3.33Å; A31-R49 PolarHBondContact O-N 3.21Å; A31-M59 HydrophobicContact CB-CE 3.82Å; A31-M59 HydrophobicContact CB-SD 3.85Å
32F98.1Very high96.4Very high74 Ų7459.5 Ų59.533%0.32530%0.295SS..EExtended strand (participates in β ladder)trans-125.8139172.4175.6-111.3000111.1M22 F34 F47 H48M22-F32 HydrophobicContact CE-CD1 3.74Å; M22-F32 HydrophobicContact CE-CE1 3.16Å; M22-F32 HydrophobicContact CE-CE2 4.16Å; M22-F32 HydrophobicContact CE-CG 4.43Å; M22-F32 HydrophobicContact CE-CZ 3.38Å; M22-F32 HydrophobicContact SD-CD1 4.49Å; M22-F32 HydrophobicContact SD-CE1 4.28Å; M22-F32 HydrophobicContact SD-CE2 4.47Å; M22-F32 HydrophobicContact SD-CZ 4.24Å; F32-F34 HydrophobicContact CE1-CB 3.69Å; F32-F34 HydrophobicContact CZ-CB 3.65Å; F32-F34 HydrophobicContact CZ-CD2 4.28Å; F32-F34 HydrophobicContact CZ-CG 4.42Å; F32-F47 VanDerWaalsContact CA-O 3.31Å; F32-F47 WeakPolarHBondContact CA-O 3.37Å; F32-F47 VanDerWaalsContact CD2-O 3.32Å; F32-F47 WeakPolarHBondContact CD2-O 3.25Å; F32-H48 AromaticContact CD2-CD2 3.84Å; F32-H48 AromaticContact CD2-CE1 3.19Å; F32-H48 WeakPolarHBondContact CD2-CE1 3.18Å; F32-H48 AromaticContact CD2-CG 3.83Å; F32-H48 AromaticContact CD2-ND1 3.43Å; F32-H48 WeakPolarHBondContact CD2-ND1 3.39Å; F32-H48 AromaticContact CD2-NE2 3.45Å; F32-H48 WeakPolarHBondContact CD2-NE2 3.4Å; F32-H48 AromaticContact CE2-CE1 3.68Å; F32-H48 AromaticContact CE2-NE2 3.51Å; F32-H48 AromaticContact CG-CE1 3.8Å; F32-H48 AromaticContact CG-ND1 3.99Å
33R97.8Very high96.5Very high91 Ų9155.8 Ų55.834%0.34328%0.277SS..EExtended strand (participates in β ladder)trans-131.8136.3168.2-176.8-177.5-65.8165.3-1.6109.3G46 F47 M59 Q60 P61R33-G46 WeakPolarHBondContact O-CA 2.96Å; R33-F47 PolarHBondContact N-O 2.94Å; R33-F47 PolarHBondContact O-N 3.26Å; R33-M59 HydrophobicContact CB-CE 3.45Å; R33-M59 VanDerWaalsContact CB-CE 3.45Å; R33-M59 VanDerWaalsContact CZ-CG 3.46Å; R33-M59 VanDerWaalsContact N-CE 3.31Å; R33-M59 PolarHBondContact NH1-O 2.97Å; R33-Q60 WeakPolarHBondContact CB-O 3.29Å; R33-Q60 WeakPolarHBondContact CD-O 3.38Å; R33-P61 PolarHBondContact NH1-O 2.94Å
34F96.9Very high96.6Very high64 Ų6452.6 Ų52.628%0.28126%0.263SS..EExtended strand (participates in β ladder)trans-127.1126.6169.6-176.2-91.4000108.7W5 L14 C18 F32 C44 F45W5-F34 HydrophobicContact CH2-CE2 4.31Å; W5-F34 AromaticContact CZ3-CE2 3.72Å; W5-F34 HydrophobicContact CZ3-CE2 3.72Å; L14-F34 HydrophobicContact CB-CZ 4.15Å; C18-F34 HydrophobicContact CB-CD2 4.18Å; C18-F34 HydrophobicContact CB-CE2 3.83Å; C18-F34 HydrophobicContact CB-CZ 4.09Å; C18-F34 VanDerWaalsContact SG-CD2 3.6Å; F32-F34 HydrophobicContact CE1-CB 3.69Å; F32-F34 HydrophobicContact CZ-CB 3.65Å; F32-F34 HydrophobicContact CZ-CD2 4.28Å; F32-F34 HydrophobicContact CZ-CG 4.42Å; F34-C44 HydrophobicContact CE2-CB 4.33Å; F34-C44 HydrophobicContact CZ-CB 3.95Å; F34-F45 WeakPolarHBondContact CA-O 3.44Å
35E95.4Very high96.6Very high42 Ų4252.6 Ų52.620%0.19626%0.263CS..EExtended strand (participates in β ladder)trans-147.4148.3173.856.417616600111.3C44 F45 P61 R63 W71E35-C44 WeakPolarHBondContact O-CA 3.48Å; E35-C44 WeakPolarHBondContact O-CB 3.34Å; E35-F45 PolarHBondContact N-O 3.05Å; E35-F45 PolarHBondContact O-N 2.86Å; E35-P61 HydrophobicContact CG-CG 3.99Å; E35-P61 VanDerWaalsContact OE1-CD 3.26Å; E35-P61 WeakPolarHBondContact OE1-CD 3.42Å; E35-P61 VanDerWaalsContact OE1-CG 3.31Å; E35-P61 WeakPolarHBondContact OE1-CG 3.46Å; E35-R63 IonicContact OE2-NH1 2.64Å; E35-R63 PolarHBondContact OE2-NH1 3.36Å; E35-W71 VanDerWaalsContact CD-CZ3 3.47Å; E35-W71 HydrophobicContact CG-CZ3 3.89Å
36N95.6Very high96.5Very high69 Ų6951 Ų5137%0.36925%0.249SC..EExtended strand (participates in β ladder)trans-96.4164.2171.769.5-17.6000111.2L14 T41 C43 C44L14-N36 HydrophobicContact CD1-CB 3.93Å; N36-T41 PolarHBondContact ND2-O 3.42Å; N36-C43 CarbonylContact C-O 3.57Å; N36-C43 VanDerWaalsContact CA-O 3.28Å; N36-C43 WeakPolarHBondContact CA-O 3.34Å; N36-C43 WeakPolarHBondContact CB-O 3.3Å; N36-C44 HydrophobicContact CB-CB 4.12Å
37V96.4Very high96.5Very high1 Ų148.5 Ų48.51%0.00624%0.238CC..EExtended strand (participates in β ladder)trans-90127.8-176.4-177.30000109.9R39 F40 T41 C43 F45 W71 L126 T128V37-R39 PolarHBondContact O-N 3.11Å; V37-F40 HydrophobicContact CB-CB 4.17Å; V37-F40 HydrophobicContact CG1-CB 4.2Å; V37-F40 HydrophobicContact CG1-CD2 4.28Å; V37-F40 CarbonylContact O-C 3.43Å; V37-F40 PolarHBondContact O-N 3.43Å; V37-F40 VanDerWaalsContact O-O 3.04Å; V37-T41 PolarHBondContact O-N 3.3Å; V37-C43 HydrophobicContact CB-CB 4.23Å; V37-C43 HydrophobicContact CG2-CB 3.99Å; V37-C43 PolarHBondContact N-O 3.34Å; V37-F45 HydrophobicContact CG2-CD2 4.21Å; V37-F45 HydrophobicContact CG2-CE2 3.85Å; V37-W71 HydrophobicContact CG1-CZ2 4.32Å; V37-W71 HydrophobicContact CG2-CE3 4.46Å; V37-L126 HydrophobicContact CB-CD2 4.3Å; V37-L126 HydrophobicContact CG1-CD2 3.8Å; V37-L126 HydrophobicContact CG2-CD2 3.56Å; V37-T128 HydrophobicContact CG1-CG2 3.92Å
38N92.5Very high96.5Very high110 Ų11048.9 Ų48.959%0.58824%0.24SC*.THydrogen-bonded Turntrans-56.1135.8173.8-62.880.3000110.7F40N38-F40 PolarHBondContact O-N 3.18Å; N38-F40 VanDerWaalsContact O-N 3.14Å
39R90.5Very high96.5Very high243 Ų24349.5 Ų49.592%0.91724%0.242SC*.THydrogen-bonded Turntrans68.6-10.7-175.1-51.1178.7176.6179.6-1.4115.8V37V37-R39 PolarHBondContact O-N 3.11Å
40F95.4Very high96.6Very high24 Ų2447.3 Ų47.311%0.10523%0.227CC..EExtended strand (participates in β ladder)trans-127.763.2171.3-63.5-79.2000108.3V37 N38 N42 C43 T128 L190 K191V37-F40 HydrophobicContact CB-CB 4.17Å; V37-F40 HydrophobicContact CG1-CB 4.2Å; V37-F40 HydrophobicContact CG1-CD2 4.28Å; V37-F40 CarbonylContact O-C 3.43Å; V37-F40 PolarHBondContact O-N 3.43Å; V37-F40 VanDerWaalsContact O-O 3.04Å; N38-F40 PolarHBondContact O-N 3.18Å; N38-F40 VanDerWaalsContact O-N 3.14Å; F40-N42 PolarHBondContact O-N 3.1Å; F40-C43 HydrophobicContact CB-CB 4.09Å; F40-C43 WeakPolarHBondContact O-CB 3.3Å; F40-C43 PolarHBondContact O-N 2.88Å; F40-T128 HydrophobicContact CD2-CG2 4.39Å; F40-T128 HydrophobicContact CE2-CG2 4.43Å; F40-L190 HydrophobicContact CD1-CD1 4.48Å; F40-L190 HydrophobicContact CD1-CD2 4.1Å; F40-L190 HydrophobicContact CD1-CG 4.35Å; F40-L190 HydrophobicContact CD2-CD2 3.97Å; F40-L190 HydrophobicContact CE1-CD2 3.84Å; F40-L190 HydrophobicContact CE1-CG 3.99Å; F40-L190 HydrophobicContact CE2-CD2 3.69Å; F40-L190 HydrophobicContact CG-CD2 4.15Å; F40-L190 HydrophobicContact CZ-CD2 3.62Å; F40-L190 HydrophobicContact CZ-CG 4.15Å; F40-K191 WeakPolarHBondContact CE1-O 3.47Å
41T93.8Very high96.5Very high95 Ų9544.3 Ų44.358%0.58321%0.212SC*.EExtended strand (participates in β ladder)trans-66.9-10.4-168.752.30000114L14 N36 V37L14-T41 WeakPolarHBondContact CD1-O 3.37Å; N36-T41 PolarHBondContact ND2-O 3.42Å; V37-T41 PolarHBondContact O-N 3.3Å
42N95Very high96.4Very high37 Ų3742.5 Ų42.520%0.19820%0.197CC..EExtended strand (participates in β ladder)trans-95.65.9171.763.3-20.8000113.9G9 S10 F40 S193G9-N42 PolarHBondContact N-O 3.21Å; S10-N42 PolarHBondContact N-O 3.36Å; S10-N42 VanDerWaalsContact N-O 3.09Å; S10-N42 VanDerWaalsContact O-CB 3.25Å; S10-N42 WeakPolarHBondContact O-CB 3.2Å; F40-N42 PolarHBondContact O-N 3.1Å; N42-S193 PolarHBondContact ND2-O 3.33Å
43C97.3Very high96.3Very high1 Ų139.3 Ų39.31%0.00718%0.183CC..EExtended strand (participates in β ladder)trans-106.2136.3166.6-57.80000108.8L7 F8 N36 V37 F40 G194L7-C43 CarbonylContact O-C 3.55Å; L7-C43 WeakPolarHBondContact O-CA 3.35Å; F8-C43 HydrophobicContact CD1-CB 4.04Å; N36-C43 CarbonylContact C-O 3.57Å; N36-C43 VanDerWaalsContact CA-O 3.28Å; N36-C43 WeakPolarHBondContact CA-O 3.34Å; N36-C43 WeakPolarHBondContact CB-O 3.3Å; V37-C43 HydrophobicContact CB-CB 4.23Å; V37-C43 HydrophobicContact CG2-CB 3.99Å; V37-C43 PolarHBondContact N-O 3.34Å; F40-C43 HydrophobicContact CB-CB 4.09Å; F40-C43 WeakPolarHBondContact O-CB 3.3Å; F40-C43 PolarHBondContact O-N 2.88Å; C43-G194 PolarHBondContact SG-O 3.11Å; C43-G194 VanDerWaalsContact SG-O 3.34Å
44C97Very high96.1Very high0 Ų035.3 Ų35.30%017%0.169CC..EExtended strand (participates in β ladder)trans-152.3162.2-179.3630000113.2W5 A6 L7 L14 F34 E35 N36W5-C44 VanDerWaalsContact CZ3-SG 3.55Å; A6-C44 CarbonylContact C-O 3.53Å; A6-C44 WeakPolarHBondContact CA-O 3.39Å; A6-C44 WeakPolarHBondContact CB-O 3.13Å; L7-C44 PolarHBondContact N-O 3.14Å; L7-C44 PolarHBondContact O-N 3.26Å; L14-C44 HydrophobicContact CD1-CB 3.85Å; F34-C44 HydrophobicContact CE2-CB 4.33Å; F34-C44 HydrophobicContact CZ-CB 3.95Å; E35-C44 WeakPolarHBondContact O-CA 3.48Å; E35-C44 WeakPolarHBondContact O-CB 3.34Å; N36-C44 HydrophobicContact CB-CB 4.12Å
45F98.2Very high95.7Very high0 Ų037.5 Ų37.50%018%0.18CC..EExtended strand (participates in β ladder)trans-125.7136.2176.1-65.8-94000109.7W5 A6 F8 F34 E35 V37 P61 W71 C73 I124 L126W5-F45 WeakPolarHBondContact O-CA 3.33Å; A6-F45 HydrophobicContact CB-CD1 3.67Å; A6-F45 HydrophobicContact CB-CE1 3.93Å; A6-F45 HydrophobicContact CB-CG 4.31Å; F8-F45 HydrophobicContact CE1-CZ 4.27Å; F8-F45 HydrophobicContact CZ-CE1 4.23Å; F8-F45 AromaticContact CZ-CZ 3.8Å; F8-F45 HydrophobicContact CZ-CZ 3.8Å; F34-F45 WeakPolarHBondContact CA-O 3.44Å; E35-F45 PolarHBondContact N-O 3.05Å; E35-F45 PolarHBondContact O-N 2.86Å; V37-F45 HydrophobicContact CG2-CD2 4.21Å; V37-F45 HydrophobicContact CG2-CE2 3.85Å; F45-P61 HydrophobicContact CB-CG 3.45Å; F45-P61 VanDerWaalsContact CB-CG 3.45Å; F45-P61 HydrophobicContact CD2-CG 4.28Å; F45-P61 HydrophobicContact CG-CG 3.87Å; F45-W71 HydrophobicContact CD2-CE3 4.24Å; F45-W71 HydrophobicContact CE2-CB 4.14Å; F45-W71 HydrophobicContact CE2-CE3 4.33Å; F45-W71 HydrophobicContact CZ-CB 4.27Å; F45-C73 HydrophobicContact CD1-CB 4.01Å; F45-C73 HydrophobicContact CE1-CB 4.44Å; F45-I124 HydrophobicContact CE1-CB 4.22Å; F45-I124 HydrophobicContact CE1-CG2 3.74Å; F45-I124 HydrophobicContact CZ-CG2 4.39Å; F45-L126 HydrophobicContact CE2-CB 4.42Å; F45-L126 HydrophobicContact CE2-CD2 3.98Å; F45-L126 HydrophobicContact CZ-CB 3.9Å; F45-L126 HydrophobicContact CZ-CD2 4.26Å
46G97.8Very high95.6Very high0 Ų042.2 Ų42.20%021%0.205CC..EExtended strand (participates in β ladder)trans-117.7129.8167.500000109W5 R33W5-G46 PolarHBondContact N-O 2.73Å; W5-G46 PolarHBondContact O-N 2.8Å; R33-G46 WeakPolarHBondContact O-CA 2.96Å
47F98.6Very high95.6Very high0 Ų046 Ų460%022%0.216CC..EExtended strand (participates in β ladder)trans-135.1120.4-177.2-173.9-107.6000111.8C2 G3 I4 F32 R33 R49 M59 Q60C2-F47 HydrophobicContact CB-CE2 3.57Å; C2-F47 HydrophobicContact CB-CZ 3.47Å; C2-F47 VanDerWaalsContact CB-CZ 3.47Å; C2-F47 VanDerWaalsContact SG-CZ 3.53Å; G3-F47 WeakPolarHBondContact O-CA 3.37Å; I4-F47 HydrophobicContact CG2-CD2 3.79Å; I4-F47 HydrophobicContact CG2-CE2 3.75Å; F32-F47 VanDerWaalsContact CA-O 3.31Å; F32-F47 WeakPolarHBondContact CA-O 3.37Å; F32-F47 VanDerWaalsContact CD2-O 3.32Å; F32-F47 WeakPolarHBondContact CD2-O 3.25Å; R33-F47 PolarHBondContact N-O 2.94Å; R33-F47 PolarHBondContact O-N 3.26Å; F47-R49 HydrophobicContact CD1-CB 4.04Å; F47-R49 HydrophobicContact CE1-CB 3.54Å; F47-R49 HydrophobicContact CE1-CG 3.72Å; F47-R49 HydrophobicContact CZ-CB 4.44Å; F47-R49 HydrophobicContact CZ-CG 4.43Å; F47-M59 HydrophobicContact CD1-CE 4.12Å; F47-M59 HydrophobicContact CD1-SD 4.29Å; F47-Q60 HydrophobicContact CB-CB 4.43Å; F47-Q60 HydrophobicContact CD1-CB 3.57Å; F47-Q60 HydrophobicContact CD1-CG 3.94Å; F47-Q60 HydrophobicContact CD2-CB 4.05Å; F47-Q60 HydrophobicContact CD2-CG 4.47Å; F47-Q60 HydrophobicContact CE1-CB 3.67Å; F47-Q60 HydrophobicContact CE1-CG 3.46Å; F47-Q60 VanDerWaalsContact CE1-CG 3.46Å; F47-Q60 HydrophobicContact CE2-CB 4.14Å; F47-Q60 VanDerWaalsContact CE2-CD 3.48Å; F47-Q60 HydrophobicContact CE2-CG 4.06Å; F47-Q60 HydrophobicContact CG-CB 3.75Å; F47-Q60 HydrophobicContact CG-CG 4.4Å; F47-Q60 HydrophobicContact CZ-CB 3.96Å; F47-Q60 HydrophobicContact CZ-CG 3.53Å
48H98.7Very high95.6Very high8 Ų846 Ų464%0.03722%0.216CC..EExtended strand (participates in β ladder)trans-100.7120170.2-67.8-82.2000109C2 G3 A21 A31 F32C2-H48 CarbonylContact C-O 3.38Å; C2-H48 WeakPolarHBondContact CA-O 3.47Å; C2-H48 WeakPolarHBondContact CB-O 3.44Å; G3-H48 PolarHBondContact N-O 3.28Å; G3-H48 PolarHBondContact O-N 3.47Å; A21-H48 PolarHBondContact O-CD2 3.07Å; A21-H48 VanDerWaalsContact O-CD2 3.32Å; A21-H48 PolarHBondContact O-NE2 3.48Å; A31-H48 WeakPolarHBondContact O-CA 3.45Å; F32-H48 AromaticContact CD2-CD2 3.84Å; F32-H48 AromaticContact CD2-CE1 3.19Å; F32-H48 WeakPolarHBondContact CD2-CE1 3.18Å; F32-H48 AromaticContact CD2-CG 3.83Å; F32-H48 AromaticContact CD2-ND1 3.43Å; F32-H48 WeakPolarHBondContact CD2-ND1 3.39Å; F32-H48 AromaticContact CD2-NE2 3.45Å; F32-H48 WeakPolarHBondContact CD2-NE2 3.4Å; F32-H48 AromaticContact CE2-CE1 3.68Å; F32-H48 AromaticContact CE2-NE2 3.51Å; F32-H48 AromaticContact CG-CE1 3.8Å; F32-H48 AromaticContact CG-ND1 3.99Å
49R98.5Very high95.9Very high15 Ų1542.1 Ų42.16%0.05720%0.195CC..EExtended strand (participates in β ladder)trans-99.6128.3-172.4-167.1168.9-168.3-133.6-3.9111.3G28 D30 A31 F47 S51 V53 D54 Q55 G58 M59G28-R49 CarbonylContact C-O 3.58Å; G28-R49 VanDerWaalsContact CA-O 3.31Å; G28-R49 WeakPolarHBondContact CA-O 3.43Å; G28-R49 PolarHBondContact O-N 2.92Å; D30-R49 WeakPolarHBondContact CA-O 3.29Å; D30-R49 VanDerWaalsContact CB-O 3.31Å; D30-R49 WeakPolarHBondContact CB-O 3.39Å; D30-R49 PolarHBondContact N-O 3.14Å; A31-R49 HydrophobicContact CB-CB 4.32Å; A31-R49 PolarHBondContact N-O 3.33Å; A31-R49 PolarHBondContact O-N 3.21Å; F47-R49 HydrophobicContact CD1-CB 4.04Å; F47-R49 HydrophobicContact CE1-CB 3.54Å; F47-R49 HydrophobicContact CE1-CG 3.72Å; F47-R49 HydrophobicContact CZ-CB 4.44Å; F47-R49 HydrophobicContact CZ-CG 4.43Å; R49-S51 PolarHBondContact NH1-OG 2.98Å; R49-V53 PolarHBondContact NH2-O 2.68Å; R49-D54 PolarHBondContact NH1-O 3.39Å; R49-D54 PolarHBondContact NH2-O 3.04Å; R49-Q55 PolarHBondContact NH1-O 3.34Å; R49-G58 PolarHBondContact NE-O 3.35Å; R49-G58 VanDerWaalsContact NH2-C 3.3Å; R49-G58 VanDerWaalsContact NH2-CA 3.29Å; R49-G58 PolarHBondContact NH2-O 3.11Å; R49-G58 VanDerWaalsContact NH2-O 3.15Å; R49-M59 HydrophobicContact CB-CE 4.37Å; R49-M59 HydrophobicContact CB-SD 3.84Å; R49-M59 WeakPolarHBondContact CD-SD 3.39Å; R49-M59 HydrophobicContact CG-SD 4.28Å
50L98.1Very high96.2Very high5 Ų530.8 Ų30.83%0.02615%0.152CC..  trans-99.9115.4151.317968.7000106.5C2 P29 V52 V359 G413 E415C2-L50 PolarHBondContact SG-N 2.99Å; C2-L50 VanDerWaalsContact SG-N 3.36Å; C2-L50 PolarHBondContact SG-O 2.75Å; P29-L50 HydrophobicContact CG-CD1 4.16Å; L50-V52 HydrophobicContact CD2-CG2 4.02Å; L50-V52 HydrophobicContact CG-CG2 4Å; L50-V52 PolarHBondContact O-N 3.36Å; L50-V359 HydrophobicContact CD1-CG1 3.87Å; L50-V359 HydrophobicContact CD2-CG1 3.79Å; L50-V359 HydrophobicContact CG-CG1 4.1Å; L50-G413 VanDerWaalsContact CD1-O 3.29Å; L50-G413 WeakPolarHBondContact CD1-O 3.2Å; L50-G413 WeakPolarHBondContact CD2-O 3.32Å; L50-E415 HydrophobicContact CD2-CB 4.07Å
51S96.3Very high96.4Very high10 Ų1029.7 Ų29.77%0.0715%0.147CC..  trans-84.598.4-174.1-1710000111.1D30 R49 Q55 R251D30-S51 PolarHBondContact OD2-N 3.4Å; R49-S51 PolarHBondContact NH1-OG 2.98Å; S51-Q55 VanDerWaalsContact OG-CA 3.32Å; S51-Q55 WeakPolarHBondContact OG-CA 3.33Å; S51-Q55 WeakPolarHBondContact OG-CG 3.43Å; S51-R251 VanDerWaalsContact O-CD 3.31Å; S51-R251 WeakPolarHBondContact O-CD 3.33Å; S51-R251 WeakPolarHBondContact O-CG 3.43Å; S51-R251 PolarHBondContact O-NH1 3.46Å
52V96.6Very high96.6Very high4 Ų425.4 Ų25.42%0.02412%0.121CC..  trans-100.4-52.5-179.4-179.90000111.1L50 E77 T249 H250 V360 E415L50-V52 HydrophobicContact CD2-CG2 4.02Å; L50-V52 HydrophobicContact CG-CG2 4Å; L50-V52 PolarHBondContact O-N 3.36Å; V52-E77 WeakPolarHBondContact CG1-OE1 3.29Å; V52-T249 VanDerWaalsContact CG1-OG1 3.26Å; V52-T249 WeakPolarHBondContact CG1-OG1 3.28Å; V52-T249 PolarHBondContact O-OG1 3.3Å; V52-H250 PolarHBondContact O-N 3.33Å; V52-V360 HydrophobicContact CG1-CG2 3.66Å; V52-E415 HydrophobicContact CG2-CB 4.34Å
53V95.6Very high96.8Very high7 Ų728.6 Ų28.64%0.04213%0.13CC..SBendtrans-110.1137.5173.2-175.50000110R49 E77 L95 M248R49-V53 PolarHBondContact NH2-O 2.68Å; V53-E77 WeakPolarHBondContact CG2-OE2 3.41Å; V53-L95 WeakPolarHBondContact CG1-O 3.33Å; V53-M248 HydrophobicContact CG2-CE 4.27Å; V53-M248 HydrophobicContact CG2-CG 4.23Å
54D93.1Very high96.8Very high7 Ų728.8 Ų28.84%0.03713%0.131CC..  trans53.187.2178.9-177.59.6000115.1R49 L56 Y57 G58 L95 V96 H250R49-D54 PolarHBondContact NH1-O 3.39Å; R49-D54 PolarHBondContact NH2-O 3.04Å; D54-L56 VanDerWaalsContact C-N 3.29Å; D54-L56 PolarHBondContact O-N 2.89Å; D54-L56 PolarHBondContact OD1-N 3.42Å; D54-Y57 PolarHBondContact OD1-N 3.3Å; D54-Y57 WeakPolarHBondContact OD2-CB 3.32Å; D54-G58 PolarHBondContact O-N 3.34Å; D54-G58 PolarHBondContact OD2-N 2.94Å; D54-L95 VanDerWaalsContact CB-C 3.48Å; D54-L95 HydrophobicContact CB-CB 3.77Å; D54-L95 WeakPolarHBondContact OD2-CA 3.45Å; D54-L95 PolarHBondContact OD2-N 3.17Å; D54-V96 HydrophobicContact CB-CB 4.21Å; D54-V96 PolarHBondContact OD2-N 3.44Å; D54-H250 PolarHBondContact N-ND1 3.07Å
55Q90.1Very high96.9Very high109 Ų10937.5 Ų37.551%0.50917%0.169SC..THydrogen-bonded Turntrans-67.2-28.3-177.1-65.3-179.70.300114R49 S51R49-Q55 PolarHBondContact NH1-O 3.34Å; S51-Q55 VanDerWaalsContact OG-CA 3.32Å; S51-Q55 WeakPolarHBondContact OG-CA 3.33Å; S51-Q55 WeakPolarHBondContact OG-CG 3.43Å
56L93.1Very high96.9Very high141 Ų14142.7 Ų42.774%0.73819%0.192SC*.THydrogen-bonded Turntrans-92.8-42.3-169.8-63.4176.8000113D54D54-L56 VanDerWaalsContact C-N 3.29Å; D54-L56 PolarHBondContact O-N 2.89Å; D54-L56 PolarHBondContact OD1-N 3.42Å
57Y94.8Very high96.9Very high148 Ų14843 Ų4358%0.5819%0.193SC*.THydrogen-bonded Turntrans-113.2-11.7-168.6-48.4-75.8000114.5D54 M59D54-Y57 PolarHBondContact OD1-N 3.3Å; D54-Y57 WeakPolarHBondContact OD2-CB 3.32Å; Y57-M59 VanDerWaalsContact C-N 3.32Å; Y57-M59 PolarHBondContact O-N 2.96Å
58G96.2Very high96.8Very high1 Ų147.4 Ų47.41%0.0122%0.222CC..  trans-84.420.7-172.300000117R49 D54R49-G58 PolarHBondContact NE-O 3.35Å; R49-G58 VanDerWaalsContact NH2-C 3.3Å; R49-G58 VanDerWaalsContact NH2-CA 3.29Å; R49-G58 PolarHBondContact NH2-O 3.11Å; R49-G58 VanDerWaalsContact NH2-O 3.15Å; D54-G58 PolarHBondContact O-N 3.34Å; D54-G58 PolarHBondContact OD2-N 2.94Å
59M98.4Very high96.8Very high30 Ų3050.3 Ų50.315%0.14823%0.233CC..  trans-73.8136.8178.6-172.965.8-175.800111.4A31 R33 F47 R49 Y57A31-M59 HydrophobicContact CB-CE 3.82Å; A31-M59 HydrophobicContact CB-SD 3.85Å; R33-M59 HydrophobicContact CB-CE 3.45Å; R33-M59 VanDerWaalsContact CB-CE 3.45Å; R33-M59 VanDerWaalsContact CZ-CG 3.46Å; R33-M59 VanDerWaalsContact N-CE 3.31Å; R33-M59 PolarHBondContact NH1-O 2.97Å; F47-M59 HydrophobicContact CD1-CE 4.12Å; F47-M59 HydrophobicContact CD1-SD 4.29Å; R49-M59 HydrophobicContact CB-CE 4.37Å; R49-M59 HydrophobicContact CB-SD 3.84Å; R49-M59 WeakPolarHBondContact CD-SD 3.39Å; R49-M59 HydrophobicContact CG-SD 4.28Å; Y57-M59 VanDerWaalsContact C-N 3.32Å; Y57-M59 PolarHBondContact O-N 2.96Å
60Q98.5Very high96.8Very high5 Ų549.6 Ų49.62%0.02323%0.23CC..SBendtrans-108.3158-173.5-39-17416.800112.6R33 F47 I62 C73 Y74R33-Q60 WeakPolarHBondContact CB-O 3.29Å; R33-Q60 WeakPolarHBondContact CD-O 3.38Å; F47-Q60 HydrophobicContact CB-CB 4.43Å; F47-Q60 HydrophobicContact CD1-CB 3.57Å; F47-Q60 HydrophobicContact CD1-CG 3.94Å; F47-Q60 HydrophobicContact CD2-CB 4.05Å; F47-Q60 HydrophobicContact CD2-CG 4.47Å; F47-Q60 HydrophobicContact CE1-CB 3.67Å; F47-Q60 HydrophobicContact CE1-CG 3.46Å; F47-Q60 VanDerWaalsContact CE1-CG 3.46Å; F47-Q60 HydrophobicContact CE2-CB 4.14Å; F47-Q60 VanDerWaalsContact CE2-CD 3.48Å; F47-Q60 HydrophobicContact CE2-CG 4.06Å; F47-Q60 HydrophobicContact CG-CB 3.75Å; F47-Q60 HydrophobicContact CG-CG 4.4Å; F47-Q60 HydrophobicContact CZ-CB 3.96Å; F47-Q60 HydrophobicContact CZ-CG 3.53Å; Q60-I62 HydrophobicContact CB-CG1 4.09Å; Q60-I62 HydrophobicContact CG-CD1 4.15Å; Q60-I62 HydrophobicContact CG-CG1 3.64Å; Q60-C73 VanDerWaalsContact OE1-CA 3.32Å; Q60-Y74 PolarHBondContact NE2-O 3.1Å; Q60-Y74 PolarHBondContact OE1-O 3.37Å
61P98.4Very high96.8Very high1 Ų149.7 Ų49.71%0.00623%0.23CC..SBendcis-56.3131.61.8-2532.6000114R33 E35 F45 R63 W71 L72R33-P61 PolarHBondContact NH1-O 2.94Å; E35-P61 HydrophobicContact CG-CG 3.99Å; E35-P61 VanDerWaalsContact OE1-CD 3.26Å; E35-P61 WeakPolarHBondContact OE1-CD 3.42Å; E35-P61 VanDerWaalsContact OE1-CG 3.31Å; E35-P61 WeakPolarHBondContact OE1-CG 3.46Å; F45-P61 HydrophobicContact CB-CG 3.45Å; F45-P61 VanDerWaalsContact CB-CG 3.45Å; F45-P61 HydrophobicContact CD2-CG 4.28Å; F45-P61 HydrophobicContact CG-CG 3.87Å; P61-R63 PolarHBondContact O-N 2.91Å; P61-W71 HydrophobicContact CB-CE3 4.2Å; P61-W71 HydrophobicContact CG-CE3 4.48Å; P61-L72 CarbonylContact C-O 3.55Å; P61-L72 WeakPolarHBondContact CA-O 3.38Å
62I98.6Very high97Very high5 Ų549.2 Ų49.23%0.02623%0.227CC..BIsolated β-bridgetrans-73.4120.6176.4-54.1177.6000107.2Q60 V64 L72 Y74 V96 L102Q60-I62 HydrophobicContact CB-CG1 4.09Å; Q60-I62 HydrophobicContact CG-CD1 4.15Å; Q60-I62 HydrophobicContact CG-CG1 3.64Å; I62-V64 HydrophobicContact CG2-CG1 4.23Å; I62-L72 HydrophobicContact CB-CB 4.29Å; I62-L72 HydrophobicContact CD1-CD2 4.19Å; I62-L72 PolarHBondContact N-O 3.46Å; I62-L72 PolarHBondContact O-N 2.68Å; I62-L72 VanDerWaalsContact O-N 3.16Å; I62-Y74 HydrophobicContact CD1-CD1 4.19Å; I62-Y74 HydrophobicContact CD1-CE1 3.93Å; I62-V96 HydrophobicContact CD1-CG1 3.63Å; I62-L102 HydrophobicContact CB-CD1 4.44Å; I62-L102 HydrophobicContact CG2-CD1 3.78Å
63R98.2Very high97.1Very high103 Ų10349 Ų4939%0.38923%0.226SC..  trans-135.4123.3176.7-65.7168.363.6-167-1107.8E35 P61 W71E35-R63 IonicContact OE2-NH1 2.64Å; E35-R63 PolarHBondContact OE2-NH1 3.36Å; P61-R63 PolarHBondContact O-N 2.91Å; R63-W71 HydrophobicContact CG-CD2 4.11Å; R63-W71 HydrophobicContact CG-CE3 4.25Å; R63-W71 HydrophobicContact CG-CG 4.33Å; R63-W71 VanDerWaalsContact CZ-CH2 3.42Å; R63-W71 VanDerWaalsContact CZ-CZ2 3.41Å
64V98.4Very high97.2Very high5 Ų548.9 Ų48.93%0.0322%0.224CC..  trans-117.6146.6-178.4-580000110.1I62 K66 F67 Q93 E99 L102I62-V64 HydrophobicContact CG2-CG1 4.23Å; V64-K66 HydrophobicContact CG2-CB 4.38Å; V64-K66 PolarHBondContact O-N 3.14Å; V64-K66 VanDerWaalsContact O-N 3.16Å; V64-F67 HydrophobicContact CG2-CB 4.23Å; V64-F67 HydrophobicContact CG2-CD2 3.46Å; V64-F67 VanDerWaalsContact CG2-CD2 3.46Å; V64-F67 HydrophobicContact CG2-CE2 4.2Å; V64-F67 HydrophobicContact CG2-CG 4.19Å; V64-F67 CarbonylContact O-C 3.6Å; V64-F67 PolarHBondContact O-N 2.94Å; V64-Q93 HydrophobicContact CB-CB 4.18Å; V64-Q93 HydrophobicContact CG1-CB 4Å; V64-E99 HydrophobicContact CG1-CG 4.16Å; V64-L102 HydrophobicContact CG1-CD1 4.1Å; V64-L102 HydrophobicContact CG2-CD1 3.92Å
65K98.1Very high97.5Very high183 Ų18348.6 Ų48.680%0.79622%0.223SC*.THydrogen-bonded Turntrans-57.8-32.5-176.7-174.8178.7178.5-1770112.3F67 Q93K65-F67 VanDerWaalsContact C-N 3.26Å; K65-F67 PolarHBondContact O-N 3.09Å; K65-Q93 VanDerWaalsContact CB-OE1 3.25Å
66K98.3Very high97.9Very high110 Ų11043.7 Ų43.748%0.47820%0.202SC..THydrogen-bonded Turntrans-63.4-31.3179.1-163.7173.6-177.7168.70112.7V64V64-K66 HydrophobicContact CG2-CB 4.38Å; V64-K66 PolarHBondContact O-N 3.14Å; V64-K66 VanDerWaalsContact O-N 3.16Å
67F98.2Very high98.2Very high7 Ų737.3 Ų37.33%0.03117%0.168CC..  trans-130.870.9-175.8-44.6-57.6000110.5V64 K65 Y69 L70 L102 H103 N106V64-F67 HydrophobicContact CG2-CB 4.23Å; V64-F67 HydrophobicContact CG2-CD2 3.46Å; V64-F67 VanDerWaalsContact CG2-CD2 3.46Å; V64-F67 HydrophobicContact CG2-CE2 4.2Å; V64-F67 HydrophobicContact CG2-CG 4.19Å; V64-F67 CarbonylContact O-C 3.6Å; V64-F67 PolarHBondContact O-N 2.94Å; K65-F67 VanDerWaalsContact C-N 3.26Å; K65-F67 PolarHBondContact O-N 3.09Å; F67-Y69 PolarHBondContact O-N 3.29Å; F67-L70 HydrophobicContact CB-CB 4.07Å; F67-L70 HydrophobicContact CB-CD1 3.64Å; F67-L70 HydrophobicContact CB-CG 3.82Å; F67-L70 HydrophobicContact CD2-CD1 4.29Å; F67-L70 HydrophobicContact CG-CD1 3.98Å; F67-L70 PolarHBondContact O-N 2.98Å; F67-L70 VanDerWaalsContact O-N 3.09Å; F67-L102 HydrophobicContact CD2-CB 3.96Å; F67-L102 HydrophobicContact CE2-CB 4.22Å; F67-H103 AromaticContact CE2-CE1 3.71Å; F67-H103 AromaticContact CE2-CG 3.86Å; F67-H103 AromaticContact CE2-ND1 3.53Å; F67-H103 AromaticContact CZ-ND1 3.59Å; F67-N106 HydrophobicContact CD1-CB 4.01Å; F67-N106 HydrophobicContact CE1-CB 3.62Å; F67-N106 WeakPolarHBondContact CE1-ND2 3.26Å; F67-N106 HydrophobicContact CZ-CB 3.9Å
68P97.5Very high98.3Very high92 Ų9230.3 Ų30.360%0.59714%0.14SC*.THydrogen-bonded Turntrans-65.7-14.4-170.527.3-35.6000114.2
69Y97.8Very high98.4Very high68 Ų6830.6 Ų30.627%0.26714%0.141SC..THydrogen-bonded Turntrans-94.3-7.9179.948-91.9000113.8F67 N106 D127 T128 A129F67-Y69 PolarHBondContact O-N 3.29Å; Y69-N106 PolarHBondContact OH-OD1 3.21Å; Y69-D127 WeakPolarHBondContact CD2-OD1 3.29Å; Y69-T128 WeakPolarHBondContact CA-OG1 3.47Å; Y69-T128 WeakPolarHBondContact CB-OG1 3.26Å; Y69-T128 PolarHBondContact O-N 2.94Å; Y69-T128 PolarHBondContact O-OG1 3.46Å; Y69-A129 HydrophobicContact CD1-CB 4.27Å; Y69-A129 HydrophobicContact CD2-CB 3.79Å; Y69-A129 HydrophobicContact CE2-CB 4.46Å; Y69-A129 HydrophobicContact CG-CB 3.69Å
70L98.8Very high98.4Very high1 Ų129.5 Ų29.51%0.00514%0.136CC..EExtended strand (participates in β ladder)trans-98.9137.2-178.7-59.3-175.3000112.1F67 L102 Y105 L125 L126 D127F67-L70 HydrophobicContact CB-CB 4.07Å; F67-L70 HydrophobicContact CB-CD1 3.64Å; F67-L70 HydrophobicContact CB-CG 3.82Å; F67-L70 HydrophobicContact CD2-CD1 4.29Å; F67-L70 HydrophobicContact CG-CD1 3.98Å; F67-L70 PolarHBondContact O-N 2.98Å; F67-L70 VanDerWaalsContact O-N 3.09Å; L70-L102 HydrophobicContact CB-CD2 3.88Å; L70-L102 HydrophobicContact CD1-CD2 4.12Å; L70-Y105 HydrophobicContact CD1-CD1 3.84Å; L70-Y105 HydrophobicContact CD1-CE1 4.37Å; L70-Y105 HydrophobicContact CD2-CD1 3.95Å; L70-Y105 HydrophobicContact CD2-CE1 3.68Å; L70-L125 HydrophobicContact CB-CD1 4.49Å; L70-L126 WeakPolarHBondContact CA-O 3.35Å; L70-D127 HydrophobicContact CD2-CB 3.63Å
71W98.8Very high98.4Very high6 Ų629.7 Ų29.72%0.02314%0.137CC..EExtended strand (participates in β ladder)trans-132.5122177.1-60.562.6000108.6E35 V37 F45 P61 R63 L125 L126E35-W71 VanDerWaalsContact CD-CZ3 3.47Å; E35-W71 HydrophobicContact CG-CZ3 3.89Å; V37-W71 HydrophobicContact CG1-CZ2 4.32Å; V37-W71 HydrophobicContact CG2-CE3 4.46Å; F45-W71 HydrophobicContact CD2-CE3 4.24Å; F45-W71 HydrophobicContact CE2-CB 4.14Å; F45-W71 HydrophobicContact CE2-CE3 4.33Å; F45-W71 HydrophobicContact CZ-CB 4.27Å; P61-W71 HydrophobicContact CB-CE3 4.2Å; P61-W71 HydrophobicContact CG-CE3 4.48Å; R63-W71 HydrophobicContact CG-CD2 4.11Å; R63-W71 HydrophobicContact CG-CE3 4.25Å; R63-W71 HydrophobicContact CG-CG 4.33Å; R63-W71 VanDerWaalsContact CZ-CH2 3.42Å; R63-W71 VanDerWaalsContact CZ-CZ2 3.41Å; W71-L125 WeakPolarHBondContact O-CA 3.28Å; W71-L126 HydrophobicContact CB-CB 4.17Å; W71-L126 HydrophobicContact CB-CD2 4.39Å; W71-L126 HydrophobicContact CG-CD2 4.24Å; W71-L126 PolarHBondContact N-O 3.24Å; W71-L126 PolarHBondContact O-N 2.63Å
72L98.9Very high98.3Very high0 Ų036 Ų360%016%0.164CC..EExtended strand (participates in β ladder)trans-122.7125.7-178.217267.3000111.1P61 I62 G98 I101 L102 F123 L125P61-L72 CarbonylContact C-O 3.55Å; P61-L72 WeakPolarHBondContact CA-O 3.38Å; I62-L72 HydrophobicContact CB-CB 4.29Å; I62-L72 HydrophobicContact CD1-CD2 4.19Å; I62-L72 PolarHBondContact N-O 3.46Å; I62-L72 PolarHBondContact O-N 2.68Å; I62-L72 VanDerWaalsContact O-N 3.16Å; L72-G98 VanDerWaalsContact CD2-O 3.29Å; L72-G98 WeakPolarHBondContact CD2-O 3.37Å; L72-I101 HydrophobicContact CD1-CG2 4.06Å; L72-I101 HydrophobicContact CD2-CB 3.77Å; L72-I101 HydrophobicContact CD2-CD1 4.25Å; L72-I101 HydrophobicContact CD2-CG2 4.03Å; L72-L102 HydrophobicContact CB-CD2 3.68Å; L72-L102 HydrophobicContact CB-CG 4.31Å; L72-L102 HydrophobicContact CD2-CD2 4.12Å; L72-L102 HydrophobicContact CD2-CG 4.03Å; L72-F123 HydrophobicContact CD1-CB 3.98Å; L72-L125 HydrophobicContact CB-CD1 4.2Å; L72-L125 HydrophobicContact CD1-CB 4.33Å
73C98.8Very high98.2Very high0 Ų038.7 Ų38.70%018%0.176CC..EExtended strand (participates in β ladder)trans-115.4129.5160.1-86.90000108.7I4 F45 Q60 F123 I124I4-C73 HydrophobicContact CB-CB 4.42Å; I4-C73 HydrophobicContact CG2-CB 4.04Å; F45-C73 HydrophobicContact CD1-CB 4.01Å; F45-C73 HydrophobicContact CE1-CB 4.44Å; Q60-C73 VanDerWaalsContact OE1-CA 3.32Å; C73-F123 CarbonylContact O-C 3.6Å; C73-F123 VanDerWaalsContact O-CA 3.28Å; C73-F123 WeakPolarHBondContact O-CA 3.5Å; C73-I124 PolarHBondContact N-O 2.89Å; C73-I124 PolarHBondContact O-N 2.81Å
74Y98.8Very high98.1Very high5 Ų533.8 Ų33.82%0.0216%0.158CC..EExtended strand (participates in β ladder)trans-142146.1172.687.1-60.1000112Q60 I62 G76 I78 D97 G98 I101 A122Q60-Y74 PolarHBondContact NE2-O 3.1Å; Q60-Y74 PolarHBondContact OE1-O 3.37Å; I62-Y74 HydrophobicContact CD1-CD1 4.19Å; I62-Y74 HydrophobicContact CD1-CE1 3.93Å; Y74-G76 VanDerWaalsContact CE2-C 3.49Å; Y74-G76 VanDerWaalsContact CE2-O 3.25Å; Y74-G76 WeakPolarHBondContact CE2-O 3.39Å; Y74-I78 HydrophobicContact CE2-CG1 4.35Å; Y74-D97 PolarHBondContact OH-OD1 2.95Å; Y74-D97 PolarHBondContact OH-OD2 3.24Å; Y74-G98 VanDerWaalsContact CZ-CA 3.41Å; Y74-G98 WeakPolarHBondContact OH-CA 3.41Å; Y74-G98 PolarHBondContact OH-N 3.2Å; Y74-I101 HydrophobicContact CD2-CD1 4.27Å; Y74-I101 HydrophobicContact CG-CD1 4.38Å; Y74-A122 CarbonylContact C-O 3.6Å; Y74-A122 WeakPolarHBondContact CA-O 3.33Å; Y74-A122 WeakPolarHBondContact CB-O 3.46Å
75N98.8Very high98Very high1 Ų136.5 Ų36.51%0.00517%0.171CC..EExtended strand (participates in β ladder)trans-109.3108.3164.5168.833.3000107.3C2 I4 R27 F121 A122 R143C2-N75 HydrophobicContact CB-CB 4.14Å; C2-N75 PolarHBondContact N-OD1 3.04Å; C2-N75 PolarHBondContact O-ND2 2.91Å; C2-N75 PolarHBondContact O-OD1 3.25Å; I4-N75 HydrophobicContact CG2-CB 4.18Å; R27-N75 PolarHBondContact NH2-ND2 2.65Å; R27-N75 VanDerWaalsContact NH2-ND2 3.2Å; N75-F121 CarbonylContact O-C 3.52Å; N75-F121 WeakPolarHBondContact O-CA 3.43Å; N75-A122 PolarHBondContact N-O 3.44Å; N75-A122 PolarHBondContact O-N 3.11Å; N75-R143 WeakPolarHBondContact O-CB 3.46Å; N75-R143 VanDerWaalsContact O-CG 3.3Å; N75-R143 WeakPolarHBondContact O-CG 3.26Å
76G98.4Very high97.9Very high6 Ų636.7 Ų36.76%0.06217%0.171CC..EExtended strand (participates in β ladder)trans173-179.5-174.500000114.3Y74 V120Y74-G76 VanDerWaalsContact CE2-C 3.49Å; Y74-G76 VanDerWaalsContact CE2-O 3.25Å; Y74-G76 WeakPolarHBondContact CE2-O 3.39Å; G76-V120 CarbonylContact C-O 3.55Å; G76-V120 WeakPolarHBondContact CA-O 3.46Å
77E98.8Very high97.8Very high7 Ų736.9 Ų36.93%0.03317%0.174CC..EExtended strand (participates in β ladder)trans-138.7118.9175.3-68.4-75.6144.600107.8V52 V53 Y79 D97 G119 V120 M248 E415 R417V52-E77 WeakPolarHBondContact CG1-OE1 3.29Å; V53-E77 WeakPolarHBondContact CG2-OE2 3.41Å; E77-Y79 HydrophobicContact CB-CD1 4.22Å; E77-Y79 HydrophobicContact CB-CE1 3.57Å; E77-Y79 HydrophobicContact CG-CE1 4.45Å; E77-D97 WeakPolarHBondContact CA-OD2 2.95Å; E77-G119 WeakPolarHBondContact O-CA 3.33Å; E77-V120 HydrophobicContact CB-CG2 4.49Å; E77-V120 PolarHBondContact N-O 2.89Å; E77-V120 PolarHBondContact O-N 3.13Å; E77-V120 VanDerWaalsContact O-N 3.08Å; E77-M248 HydrophobicContact CB-CE 4.03Å; E77-M248 WeakPolarHBondContact OE2-CE 3.48Å; E77-E415 WeakPolarHBondContact CG-OE2 3.4Å; E77-R417 IonicContact OE1-NH2 2.67Å; E77-R417 IonicContact OE2-CZ 3.82Å; E77-R417 IonicContact OE2-NH2 3.89Å; E77-R417 PolarHBondContact OE2-NH2 3.13Å
78I98.6Very high97.7Very high0 Ų038 Ų380%018%0.179CC..EExtended strand (participates in β ladder)trans-98.892.6177.3-47.7-54.5000109.1Y74 N80 F81 D97 V100 I101 L117 D118 F121Y74-I78 HydrophobicContact CE2-CG1 4.35Å; I78-N80 VanDerWaalsContact C-N 3.27Å; I78-N80 WeakPolarHBondContact CG2-OD1 3.03Å; I78-N80 PolarHBondContact O-N 3.34Å; I78-F81 HydrophobicContact CB-CB 4.38Å; I78-F81 HydrophobicContact CG2-CB 4.31Å; I78-F81 WeakPolarHBondContact O-CB 3.46Å; I78-F81 VanDerWaalsContact O-CD1 3.32Å; I78-F81 WeakPolarHBondContact O-CD1 3.5Å; I78-F81 PolarHBondContact O-N 3.2Å; I78-D97 HydrophobicContact CB-CB 4.38Å; I78-D97 PolarHBondContact N-OD2 3.5Å; I78-V100 HydrophobicContact CB-CG1 4.18Å; I78-V100 HydrophobicContact CG1-CG1 4.29Å; I78-V100 HydrophobicContact CG2-CG1 3.79Å; I78-I101 HydrophobicContact CD1-CD1 4.39Å; I78-I101 HydrophobicContact CG1-CD1 4.37Å; I78-L117 HydrophobicContact CD1-CB 4.31Å; I78-L117 HydrophobicContact CD1-CD1 4.16Å; I78-L117 HydrophobicContact CD1-CD2 4.23Å; I78-L117 HydrophobicContact CD1-CG 4.44Å; I78-L117 HydrophobicContact CG1-CD2 4.4Å; I78-L117 HydrophobicContact CG2-CB 4.47Å; I78-L117 HydrophobicContact CG2-CD2 3.78Å; I78-D118 CarbonylContact C-O 3.35Å; I78-F121 HydrophobicContact CD1-CB 4.09Å; I78-F121 HydrophobicContact CD1-CD1 3.74Å; I78-F121 HydrophobicContact CD1-CG 4.21Å
79Y98.3Very high97.7Very high8 Ų836.4 Ų36.43%0.03118%0.179CC..THydrogen-bonded Turntrans-65.8-26.9-169.5-52.5-60.2000113.9E77 D118 K245 R246 M248E77-Y79 HydrophobicContact CB-CD1 4.22Å; E77-Y79 HydrophobicContact CB-CE1 3.57Å; E77-Y79 HydrophobicContact CG-CE1 4.45Å; Y79-D118 WeakPolarHBondContact CB-O 3.41Å; Y79-D118 PolarHBondContact N-O 3.23Å; Y79-K245 HydrophobicContact CD2-CD 4.34Å; Y79-K245 HydrophobicContact CD2-CG 4.44Å; Y79-K245 HydrophobicContact CG-CD 4.38Å; Y79-K245 HydrophobicContact CG-CG 4.16Å; Y79-R246 HydrophobicContact CD1-CG 4.11Å; Y79-R246 HydrophobicContact CD2-CG 4.38Å; Y79-R246 HydrophobicContact CE1-CB 4.35Å; Y79-R246 HydrophobicContact CE1-CG 3.65Å; Y79-R246 HydrophobicContact CE2-CG 3.97Å; Y79-R246 HydrophobicContact CG-CG 4.46Å; Y79-M248 HydrophobicContact CD1-CE 4.04Å
80N97.9Very high97.7Very high7 Ų734.1 Ų34.14%0.03717%0.17CC..THydrogen-bonded Turntrans-92.510.6179.170.6-19.2000114.7I78 K82 Q83 L84 M116 D118I78-N80 VanDerWaalsContact C-N 3.27Å; I78-N80 WeakPolarHBondContact CG2-OD1 3.03Å; I78-N80 PolarHBondContact O-N 3.34Å; N80-K82 VanDerWaalsContact C-N 3.26Å; N80-K82 PolarHBondContact O-N 3.03Å; N80-Q83 PolarHBondContact O-N 3.15Å; N80-Q83 VanDerWaalsContact O-N 3.12Å; N80-Q83 PolarHBondContact O-OE1 3.37Å; N80-L84 WeakPolarHBondContact O-CG 3.25Å; N80-L84 PolarHBondContact O-N 3.26Å; N80-L84 WeakPolarHBondContact OD1-CD1 3.42Å; N80-M116 PolarHBondContact ND2-O 3.46Å; N80-D118 HydrophobicContact CB-CB 3.73Å; N80-D118 VanDerWaalsContact CG-CB 3.42Å; N80-D118 PolarHBondContact ND2-N 3Å; N80-D118 PolarHBondContact OD1-N 3.37Å; N80-D118 VanDerWaalsContact OD1-N 3.11Å
81F97.8Very high97.7Very high9 Ų941.3 Ų41.34%0.03920%0.204CC..Hα-helixtrans-59.4-34.6-171.184.8-86.7000113.8I78 Q85 Y92 D97 V100 M248I78-F81 HydrophobicContact CB-CB 4.38Å; I78-F81 HydrophobicContact CG2-CB 4.31Å; I78-F81 WeakPolarHBondContact O-CB 3.46Å; I78-F81 VanDerWaalsContact O-CD1 3.32Å; I78-F81 WeakPolarHBondContact O-CD1 3.5Å; I78-F81 PolarHBondContact O-N 3.2Å; F81-Q85 VanDerWaalsContact O-CB 3.3Å; F81-Q85 WeakPolarHBondContact O-CB 3.31Å; F81-Q85 PolarHBondContact O-N 3.01Å; F81-Y92 AromaticContact CD2-CE2 3.9Å; F81-Y92 HydrophobicContact CD2-CE2 3.9Å; F81-Y92 HydrophobicContact CE2-CE2 4.41Å; F81-Y92 PolarHBondContact O-OH 2.94Å; F81-D97 HydrophobicContact CB-CB 4.12Å; F81-D97 HydrophobicContact CD1-CB 3.44Å; F81-D97 VanDerWaalsContact CD1-CB 3.44Å; F81-D97 HydrophobicContact CD2-CB 4.35Å; F81-D97 HydrophobicContact CE1-CB 3.79Å; F81-D97 HydrophobicContact CG-CB 3.72Å; F81-D97 HydrophobicContact CZ-CB 4.35Å; F81-V100 HydrophobicContact CB-CB 4.1Å; F81-V100 HydrophobicContact CB-CG1 4Å; F81-M248 HydrophobicContact CD1-CE 4.44Å; F81-M248 HydrophobicContact CD1-SD 3.49Å; F81-M248 WeakPolarHBondContact CD1-SD 3.4Å; F81-M248 HydrophobicContact CE1-CG 4.18Å; F81-M248 HydrophobicContact CE1-SD 3.35Å; F81-M248 WeakPolarHBondContact CE1-SD 3.44Å
82K96.4Very high97.6Very high134 Ų13442.8 Ų42.858%0.58321%0.21SC*.Hα-helixtrans-72.4-38.1178.9-68.4-172.6178.5179.90112N80 Q85 K86N80-K82 VanDerWaalsContact C-N 3.26Å; N80-K82 PolarHBondContact O-N 3.03Å; K82-Q85 PolarHBondContact O-N 3.16Å; K82-K86 PolarHBondContact O-N 3.44Å
83Q95.9Very high97.6Very high60 Ų6048 Ų4828%0.2823%0.234SC..Hα-helixtrans-63.1-47.6175.5-67.280.2-8.600109.5N80 Q85 K86 Q87 T218N80-Q83 PolarHBondContact O-N 3.15Å; N80-Q83 VanDerWaalsContact O-N 3.12Å; N80-Q83 PolarHBondContact O-OE1 3.37Å; Q83-Q85 PolarHBondContact O-N 3.49Å; Q83-K86 PolarHBondContact O-N 3.35Å; Q83-Q87 VanDerWaalsContact O-CB 3.24Å; Q83-Q87 WeakPolarHBondContact O-CB 3.48Å; Q83-Q87 PolarHBondContact O-N 2.9Å; Q83-T218 HydrophobicContact CG-CG2 4.31Å
84L96.6Very high97.5Very high0 Ų048.6 Ų48.60%024%0.238CC..Hα-helixtrans-62.7-42.3176.6-63.8171000112.1N80 K86 Q87 F88 V100 L104 M116N80-L84 WeakPolarHBondContact O-CG 3.25Å; N80-L84 PolarHBondContact O-N 3.26Å; N80-L84 WeakPolarHBondContact OD1-CD1 3.42Å; L84-K86 PolarHBondContact O-N 2.95Å; L84-Q87 PolarHBondContact O-N 3.07Å; L84-F88 HydrophobicContact CB-CD2 4.44Å; L84-F88 HydrophobicContact CD2-CD2 4.4Å; L84-F88 HydrophobicContact CD2-CE2 3.8Å; L84-F88 WeakPolarHBondContact O-CD2 3.29Å; L84-F88 PolarHBondContact O-N 3.16Å; L84-V100 HydrophobicContact CB-CG2 3.82Å; L84-V100 HydrophobicContact CD1-CG2 3.72Å; L84-V100 HydrophobicContact CG-CG2 4.46Å; L84-L104 HydrophobicContact CD1-CD1 4.07Å; L84-M116 HydrophobicContact CD2-CE 3.4Å; L84-M116 VanDerWaalsContact CD2-CE 3.4Å
85Q97Very high97.4Very high63 Ų6353.6 Ų53.629%0.29426%0.264SS..Hα-helixtrans-55.9-50.6174.9-174.2-1721700111.2F81 K82 Q83 G89 F90 Y92F81-Q85 VanDerWaalsContact O-CB 3.3Å; F81-Q85 WeakPolarHBondContact O-CB 3.31Å; F81-Q85 PolarHBondContact O-N 3.01Å; K82-Q85 PolarHBondContact O-N 3.16Å; Q83-Q85 PolarHBondContact O-N 3.49Å; Q85-G89 WeakPolarHBondContact O-CA 3.25Å; Q85-G89 PolarHBondContact O-N 3.44Å; Q85-F90 HydrophobicContact CG-CB 4.26Å; Q85-F90 VanDerWaalsContact CG-O 3.25Å; Q85-F90 WeakPolarHBondContact CG-O 3.42Å; Q85-F90 PolarHBondContact NE2-O 2.79Å; Q85-F90 PolarHBondContact O-N 3.35Å; Q85-Y92 HydrophobicContact CB-CE1 4.33Å; Q85-Y92 HydrophobicContact CB-CE2 4.42Å; Q85-Y92 HydrophobicContact CG-CD1 4.25Å; Q85-Y92 HydrophobicContact CG-CE1 4.01Å; Q85-Y92 HydrophobicContact CG-CE2 4.38Å
86K96.2Very high97.4Very high186 Ų18653.8 Ų53.881%0.80927%0.266SS*.Hα-helixtrans-65-46.5179.1-176.3-177.6176.7-173.60111.6K82 Q83 L84 F88 G89K82-K86 PolarHBondContact O-N 3.44Å; Q83-K86 PolarHBondContact O-N 3.35Å; L84-K86 PolarHBondContact O-N 2.95Å; K86-F88 PolarHBondContact O-N 2.83Å; K86-G89 PolarHBondContact O-N 2.99Å
87Q95.1Very high97.4Very high115 Ų11553.6 Ų53.654%0.53726%0.263SS..Hα-helixtrans-61.3-42.6-176179.364.814.100112.4Q83 L84 Y216Q83-Q87 VanDerWaalsContact O-CB 3.24Å; Q83-Q87 WeakPolarHBondContact O-CB 3.48Å; Q83-Q87 PolarHBondContact O-N 2.9Å; L84-Q87 PolarHBondContact O-N 3.07Å; Q87-Y216 HydrophobicContact CB-CD1 4.4Å; Q87-Y216 HydrophobicContact CG-CD1 3.6Å; Q87-Y216 HydrophobicContact CG-CE1 3.6Å
88F96.6Very high97.4Very high30 Ų3053.2 Ų53.213%0.13226%0.261CS..Hα-helixtrans-100.51.6-176.1-60.8-58.7000113.8L84 K86 F90 L104 M116 Y216L84-F88 HydrophobicContact CB-CD2 4.44Å; L84-F88 HydrophobicContact CD2-CD2 4.4Å; L84-F88 HydrophobicContact CD2-CE2 3.8Å; L84-F88 WeakPolarHBondContact O-CD2 3.29Å; L84-F88 PolarHBondContact O-N 3.16Å; K86-F88 PolarHBondContact O-N 2.83Å; F88-F90 VanDerWaalsContact C-N 3.35Å; F88-F90 HydrophobicContact CB-CD1 3.9Å; F88-F90 HydrophobicContact CB-CD2 4.07Å; F88-F90 HydrophobicContact CB-CE1 3.5Å; F88-F90 HydrophobicContact CB-CE2 3.69Å; F88-F90 HydrophobicContact CB-CG 4.18Å; F88-F90 HydrophobicContact CB-CZ 3.39Å; F88-F90 AromaticContact CD2-CE2 3.76Å; F88-F90 HydrophobicContact CD2-CE2 3.76Å; F88-F90 AromaticContact CD2-CZ 3.83Å; F88-F90 HydrophobicContact CD2-CZ 3.83Å; F88-F90 HydrophobicContact CG-CE1 4.37Å; F88-F90 HydrophobicContact CG-CE2 4.12Å; F88-F90 AromaticContact CG-CZ 3.85Å; F88-F90 HydrophobicContact CG-CZ 3.85Å; F88-F90 PolarHBondContact O-N 3.44Å; F88-L104 HydrophobicContact CD2-CD2 4.27Å; F88-L104 HydrophobicContact CE2-CD2 4.09Å; F88-M116 HydrophobicContact CE2-CE 3.88Å; F88-M116 HydrophobicContact CZ-CE 3.96Å; F88-Y216 HydrophobicContact CZ-CE1 4.22Å
89G97.6Very high97.4Very high58 Ų5853.3 Ų53.360%0.59826%0.262SS*.THydrogen-bonded Turntrans62.739.3179.800000112.8Q85 K86Q85-G89 WeakPolarHBondContact O-CA 3.25Å; Q85-G89 PolarHBondContact O-N 3.44Å; K86-G89 PolarHBondContact O-N 2.99Å
90F97.9Very high97.4Very high20 Ų2052.9 Ų52.99%0.08826%0.26CS..  trans-76.5128.5-178.7-60.3-38.9000111.9Q85 F88 Y92 H103 L104Q85-F90 HydrophobicContact CG-CB 4.26Å; Q85-F90 VanDerWaalsContact CG-O 3.25Å; Q85-F90 WeakPolarHBondContact CG-O 3.42Å; Q85-F90 PolarHBondContact NE2-O 2.79Å; Q85-F90 PolarHBondContact O-N 3.35Å; F88-F90 VanDerWaalsContact C-N 3.35Å; F88-F90 HydrophobicContact CB-CD1 3.9Å; F88-F90 HydrophobicContact CB-CD2 4.07Å; F88-F90 HydrophobicContact CB-CE1 3.5Å; F88-F90 HydrophobicContact CB-CE2 3.69Å; F88-F90 HydrophobicContact CB-CG 4.18Å; F88-F90 HydrophobicContact CB-CZ 3.39Å; F88-F90 AromaticContact CD2-CE2 3.76Å; F88-F90 HydrophobicContact CD2-CE2 3.76Å; F88-F90 AromaticContact CD2-CZ 3.83Å; F88-F90 HydrophobicContact CD2-CZ 3.83Å; F88-F90 HydrophobicContact CG-CE1 4.37Å; F88-F90 HydrophobicContact CG-CE2 4.12Å; F88-F90 AromaticContact CG-CZ 3.85Å; F88-F90 HydrophobicContact CG-CZ 3.85Å; F88-F90 PolarHBondContact O-N 3.44Å; F90-Y92 HydrophobicContact CB-CD1 3.85Å; F90-Y92 HydrophobicContact CB-CE1 3.39Å; F90-Y92 HydrophobicContact CD2-CE1 4.08Å; F90-Y92 HydrophobicContact CG-CE1 4.16Å; F90-H103 HydrophobicContact CB-CB 4.28Å; F90-H103 HydrophobicContact CD1-CB 3.75Å; F90-H103 HydrophobicContact CD2-CB 3.62Å; F90-H103 HydrophobicContact CE1-CB 3.83Å; F90-H103 HydrophobicContact CE2-CB 3.71Å; F90-H103 HydrophobicContact CG-CB 3.64Å; F90-H103 AromaticContact CG-CG 3.91Å; F90-H103 HydrophobicContact CZ-CB 3.81Å; F90-L104 HydrophobicContact CE2-CD2 4.12Å; F90-L104 HydrophobicContact CE2-CG 4.33Å; F90-L104 HydrophobicContact CZ-CD2 4.21Å
91E97.8Very high97.5Very high152 Ų15252.6 Ų52.671%0.7126%0.258SS*.  trans-91.5108.1172.7-67177.5175.100109.7H103E91-H103 PolarHBondContact O-CE1 3.2Å
92Y98.2Very high97.5Very high37 Ų3752.1 Ų52.115%0.14526%0.256CS..  trans-88.3148.5-177.8-72.910.1000112F81 Q85 F90 T94 E99 V100 H103F81-Y92 AromaticContact CD2-CE2 3.9Å; F81-Y92 HydrophobicContact CD2-CE2 3.9Å; F81-Y92 HydrophobicContact CE2-CE2 4.41Å; F81-Y92 PolarHBondContact O-OH 2.94Å; Q85-Y92 HydrophobicContact CB-CE1 4.33Å; Q85-Y92 HydrophobicContact CB-CE2 4.42Å; Q85-Y92 HydrophobicContact CG-CD1 4.25Å; Q85-Y92 HydrophobicContact CG-CE1 4.01Å; Q85-Y92 HydrophobicContact CG-CE2 4.38Å; F90-Y92 HydrophobicContact CB-CD1 3.85Å; F90-Y92 HydrophobicContact CB-CE1 3.39Å; F90-Y92 HydrophobicContact CD2-CE1 4.08Å; F90-Y92 HydrophobicContact CG-CE1 4.16Å; Y92-T94 WeakPolarHBondContact CB-O 3.44Å; Y92-E99 WeakPolarHBondContact CA-OE1 3.49Å; Y92-E99 HydrophobicContact CD1-CG 4.42Å; Y92-E99 HydrophobicContact CD2-CB 4.22Å; Y92-E99 HydrophobicContact CD2-CG 4.41Å; Y92-E99 HydrophobicContact CE2-CB 4.34Å; Y92-E99 HydrophobicContact CG-CG 4.28Å; Y92-V100 VanDerWaalsContact OH-CA 3.29Å; Y92-V100 WeakPolarHBondContact OH-CA 3.44Å; Y92-V100 WeakPolarHBondContact OH-CB 3.21Å; Y92-V100 WeakPolarHBondContact OH-CG2 3.13Å; Y92-H103 AromaticContact CD1-CD2 3.49Å; Y92-H103 VanDerWaalsContact CD1-CD2 3.49Å; Y92-H103 WeakPolarHBondContact CD1-CD2 3.47Å; Y92-H103 AromaticContact CD1-CE1 3.95Å; Y92-H103 AromaticContact CD1-NE2 3.27Å; Y92-H103 VanDerWaalsContact CD1-NE2 3.27Å; Y92-H103 WeakPolarHBondContact CD1-NE2 3.21Å; Y92-H103 AromaticContact CE1-CD2 3.29Å; Y92-H103 WeakPolarHBondContact CE1-CD2 3.43Å; Y92-H103 AromaticContact CE1-CG 3.91Å; Y92-H103 AromaticContact CE1-NE2 3.62Å
93Q98.3Very high97.6Very high111 Ų11146 Ų4652%0.51923%0.23SC..SBendtrans-92-30.8172.2-169.2-177.1-69.600112.2V64 K65 E99V64-Q93 HydrophobicContact CB-CB 4.18Å; V64-Q93 HydrophobicContact CG1-CB 4Å; K65-Q93 VanDerWaalsContact CB-OE1 3.25Å; Q93-E99 PolarHBondContact N-OE1 3.5Å; Q93-E99 PolarHBondContact N-OE2 2.81Å
94T97.4Very high97.8Very high12 Ų1243.1 Ų43.17%0.07422%0.216CC..SBendtrans-112.1178.617974.10000110.2Y92 V96 E99Y92-T94 WeakPolarHBondContact CB-O 3.44Å; T94-V96 WeakPolarHBondContact OG1-CG1 3.26Å; T94-V96 PolarHBondContact OG1-N 3.35Å; T94-E99 WeakPolarHBondContact CA-OE2 3.34Å; T94-E99 VanDerWaalsContact CB-OE2 3.28Å; T94-E99 WeakPolarHBondContact CB-OE2 3.48Å; T94-E99 PolarHBondContact N-OE2 3.37Å; T94-E99 PolarHBondContact OG1-OE2 3.39Å
95L96.9Very high97.9Very high110 Ų11044 Ų4458%0.57622%0.22SC*.  trans-111.37.9172.7-55.2174.8000111.8V53 D54V53-L95 WeakPolarHBondContact CG1-O 3.33Å; D54-L95 VanDerWaalsContact CB-C 3.48Å; D54-L95 HydrophobicContact CB-CB 3.77Å; D54-L95 WeakPolarHBondContact OD2-CA 3.45Å; D54-L95 PolarHBondContact OD2-N 3.17Å
96V98Very high97.9Very high5 Ų544.5 Ų44.53%0.0323%0.225CC..  trans-77.7138.7178.584.60000110D54 I62 T94 G98 E99D54-V96 HydrophobicContact CB-CB 4.21Å; D54-V96 PolarHBondContact OD2-N 3.44Å; I62-V96 HydrophobicContact CD1-CG1 3.63Å; T94-V96 WeakPolarHBondContact OG1-CG1 3.26Å; T94-V96 PolarHBondContact OG1-N 3.35Å; V96-G98 VanDerWaalsContact C-N 3.29Å; V96-G98 PolarHBondContact O-N 2.69Å; V96-E99 HydrophobicContact CG1-CB 4.37Å; V96-E99 PolarHBondContact O-N 3.37Å
97D98.5Very high98Very high1 Ų142.3 Ų42.31%0.00521%0.211CC..THydrogen-bonded Turntrans-59.5-38.9-177.655.2-66.9000112.3Y74 E77 I78 F81 E99 V100 M248Y74-D97 PolarHBondContact OH-OD1 2.95Å; Y74-D97 PolarHBondContact OH-OD2 3.24Å; E77-D97 WeakPolarHBondContact CA-OD2 2.95Å; I78-D97 HydrophobicContact CB-CB 4.38Å; I78-D97 PolarHBondContact N-OD2 3.5Å; F81-D97 HydrophobicContact CB-CB 4.12Å; F81-D97 HydrophobicContact CD1-CB 3.44Å; F81-D97 VanDerWaalsContact CD1-CB 3.44Å; F81-D97 HydrophobicContact CD2-CB 4.35Å; F81-D97 HydrophobicContact CE1-CB 3.79Å; F81-D97 HydrophobicContact CG-CB 3.72Å; F81-D97 HydrophobicContact CZ-CB 4.35Å; D97-E99 PolarHBondContact O-N 2.83Å; D97-E99 VanDerWaalsContact O-N 3.14Å; D97-V100 WeakPolarHBondContact O-CG1 3.35Å; D97-V100 PolarHBondContact O-N 3.38Å; D97-M248 HydrophobicContact CB-CE 3.79Å; D97-M248 HydrophobicContact CB-SD 4.32Å
98G98.4Very high98Very high0 Ų038.5 Ų38.50%020%0.203CC..THydrogen-bonded Turntrans-64.9-14.4-178.700000115.9L72 Y74 V96 V100 I101L72-G98 VanDerWaalsContact CD2-O 3.29Å; L72-G98 WeakPolarHBondContact CD2-O 3.37Å; Y74-G98 VanDerWaalsContact CZ-CA 3.41Å; Y74-G98 WeakPolarHBondContact OH-CA 3.41Å; Y74-G98 PolarHBondContact OH-N 3.2Å; V96-G98 VanDerWaalsContact C-N 3.29Å; V96-G98 PolarHBondContact O-N 2.69Å; G98-V100 PolarHBondContact O-N 2.82Å; G98-I101 WeakPolarHBondContact O-CB 3.49Å; G98-I101 PolarHBondContact O-N 3.44Å; G98-I101 VanDerWaalsContact O-N 3.12Å
99E98.7Very high98.1Very high1 Ų138.3 Ų38.31%0.00521%0.209CC..Hα-helixtrans-59.4-28.6174.9-176.4173.9158.100111.6V64 Y92 Q93 T94 V96 D97 I101 L102 H103V64-E99 HydrophobicContact CG1-CG 4.16Å; Y92-E99 WeakPolarHBondContact CA-OE1 3.49Å; Y92-E99 HydrophobicContact CD1-CG 4.42Å; Y92-E99 HydrophobicContact CD2-CB 4.22Å; Y92-E99 HydrophobicContact CD2-CG 4.41Å; Y92-E99 HydrophobicContact CE2-CB 4.34Å; Y92-E99 HydrophobicContact CG-CG 4.28Å; Q93-E99 PolarHBondContact N-OE1 3.5Å; Q93-E99 PolarHBondContact N-OE2 2.81Å; T94-E99 WeakPolarHBondContact CA-OE2 3.34Å; T94-E99 VanDerWaalsContact CB-OE2 3.28Å; T94-E99 WeakPolarHBondContact CB-OE2 3.48Å; T94-E99 PolarHBondContact N-OE2 3.37Å; T94-E99 PolarHBondContact OG1-OE2 3.39Å; V96-E99 HydrophobicContact CG1-CB 4.37Å; V96-E99 PolarHBondContact O-N 3.37Å; D97-E99 PolarHBondContact O-N 2.83Å; D97-E99 VanDerWaalsContact O-N 3.14Å; E99-I101 PolarHBondContact O-N 3.49Å; E99-I101 VanDerWaalsContact O-N 3.11Å; E99-L102 WeakPolarHBondContact O-CB 3.37Å; E99-L102 PolarHBondContact O-N 3.13Å; E99-H103 PolarHBondContact O-CD2 3.49Å; E99-H103 PolarHBondContact O-N 3.35Å; E99-H103 IonicContact OE1-CD2 2.89Å; E99-H103 IonicContact OE1-CE1 2.96Å; E99-H103 IonicContact OE1-NE2 3.33Å; E99-H103 PolarHBondContact OE1-NE2 3.13Å
100V98.7Very high98.1Very high0 Ų036.2 Ų36.20%018%0.184CC..Hα-helixtrans-54.3-32.1176.572.70000113.3I78 F81 L84 Y92 D97 G98 L102 H103 L104 L117I78-V100 HydrophobicContact CB-CG1 4.18Å; I78-V100 HydrophobicContact CG1-CG1 4.29Å; I78-V100 HydrophobicContact CG2-CG1 3.79Å; F81-V100 HydrophobicContact CB-CB 4.1Å; F81-V100 HydrophobicContact CB-CG1 4Å; L84-V100 HydrophobicContact CB-CG2 3.82Å; L84-V100 HydrophobicContact CD1-CG2 3.72Å; L84-V100 HydrophobicContact CG-CG2 4.46Å; Y92-V100 VanDerWaalsContact OH-CA 3.29Å; Y92-V100 WeakPolarHBondContact OH-CA 3.44Å; Y92-V100 WeakPolarHBondContact OH-CB 3.21Å; Y92-V100 WeakPolarHBondContact OH-CG2 3.13Å; D97-V100 WeakPolarHBondContact O-CG1 3.35Å; D97-V100 PolarHBondContact O-N 3.38Å; G98-V100 PolarHBondContact O-N 2.82Å; V100-L102 VanDerWaalsContact C-N 3.29Å; V100-L102 PolarHBondContact O-N 2.93Å; V100-H103 PolarHBondContact O-N 2.92Å; V100-L104 HydrophobicContact CG2-CD1 4.04Å; V100-L104 HydrophobicContact CG2-CG 4.12Å; V100-L104 WeakPolarHBondContact O-CB 3.25Å; V100-L104 WeakPolarHBondContact O-CG 3.27Å; V100-L104 PolarHBondContact O-N 3.42Å; V100-L117 HydrophobicContact CG1-CD2 4.15Å
101I98.8Very high98Very high0 Ų041 Ų410%021%0.207CC..Hα-helixtrans-62.2-39.6179.3-62.1173.8000110L72 Y74 I78 G98 E99 Y105 T113 L117 F123L72-I101 HydrophobicContact CD1-CG2 4.06Å; L72-I101 HydrophobicContact CD2-CB 3.77Å; L72-I101 HydrophobicContact CD2-CD1 4.25Å; L72-I101 HydrophobicContact CD2-CG2 4.03Å; Y74-I101 HydrophobicContact CD2-CD1 4.27Å; Y74-I101 HydrophobicContact CG-CD1 4.38Å; I78-I101 HydrophobicContact CD1-CD1 4.39Å; I78-I101 HydrophobicContact CG1-CD1 4.37Å; G98-I101 WeakPolarHBondContact O-CB 3.49Å; G98-I101 PolarHBondContact O-N 3.44Å; G98-I101 VanDerWaalsContact O-N 3.12Å; E99-I101 PolarHBondContact O-N 3.49Å; E99-I101 VanDerWaalsContact O-N 3.11Å; I101-Y105 WeakPolarHBondContact O-CB 3.4Å; I101-Y105 PolarHBondContact O-N 3.26Å; I101-T113 HydrophobicContact CB-CG2 4.49Å; I101-T113 HydrophobicContact CG2-CG2 3.95Å; I101-L117 HydrophobicContact CD1-CD1 4.26Å; I101-L117 HydrophobicContact CG1-CD1 4.07Å; I101-L117 HydrophobicContact CG1-CD2 4.01Å; I101-F123 HydrophobicContact CD1-CD1 4.45Å
102L98.8Very high97.8Very high0 Ų037.2 Ų37.20%019%0.189CC..Hα-helixtrans-65.5-43.2177.4-62.2-178.7000111.6I62 V64 F67 L70 L72 E99 V100 N106 L125I62-L102 HydrophobicContact CB-CD1 4.44Å; I62-L102 HydrophobicContact CG2-CD1 3.78Å; V64-L102 HydrophobicContact CG1-CD1 4.1Å; V64-L102 HydrophobicContact CG2-CD1 3.92Å; F67-L102 HydrophobicContact CD2-CB 3.96Å; F67-L102 HydrophobicContact CE2-CB 4.22Å; L70-L102 HydrophobicContact CB-CD2 3.88Å; L70-L102 HydrophobicContact CD1-CD2 4.12Å; L72-L102 HydrophobicContact CB-CD2 3.68Å; L72-L102 HydrophobicContact CB-CG 4.31Å; L72-L102 HydrophobicContact CD2-CD2 4.12Å; L72-L102 HydrophobicContact CD2-CG 4.03Å; E99-L102 WeakPolarHBondContact O-CB 3.37Å; E99-L102 PolarHBondContact O-N 3.13Å; V100-L102 VanDerWaalsContact C-N 3.29Å; V100-L102 PolarHBondContact O-N 2.93Å; L102-N106 WeakPolarHBondContact O-CB 3.49Å; L102-N106 PolarHBondContact O-N 3.02Å; L102-L125 HydrophobicContact CD2-CD1 3.74Å
103H98.8Very high97.8Very high4 Ų435.4 Ų35.42%0.01918%0.182CC..Hα-helixtrans-70.6-42.1-179.2-69-86.8000112.3F67 F90 E91 Y92 E99 V100 R107F67-H103 AromaticContact CE2-CE1 3.71Å; F67-H103 AromaticContact CE2-CG 3.86Å; F67-H103 AromaticContact CE2-ND1 3.53Å; F67-H103 AromaticContact CZ-ND1 3.59Å; F90-H103 HydrophobicContact CB-CB 4.28Å; F90-H103 HydrophobicContact CD1-CB 3.75Å; F90-H103 HydrophobicContact CD2-CB 3.62Å; F90-H103 HydrophobicContact CE1-CB 3.83Å; F90-H103 HydrophobicContact CE2-CB 3.71Å; F90-H103 HydrophobicContact CG-CB 3.64Å; F90-H103 AromaticContact CG-CG 3.91Å; F90-H103 HydrophobicContact CZ-CB 3.81Å; E91-H103 PolarHBondContact O-CE1 3.2Å; Y92-H103 AromaticContact CD1-CD2 3.49Å; Y92-H103 VanDerWaalsContact CD1-CD2 3.49Å; Y92-H103 WeakPolarHBondContact CD1-CD2 3.47Å; Y92-H103 AromaticContact CD1-CE1 3.95Å; Y92-H103 AromaticContact CD1-NE2 3.27Å; Y92-H103 VanDerWaalsContact CD1-NE2 3.27Å; Y92-H103 WeakPolarHBondContact CD1-NE2 3.21Å; Y92-H103 AromaticContact CE1-CD2 3.29Å; Y92-H103 WeakPolarHBondContact CE1-CD2 3.43Å; Y92-H103 AromaticContact CE1-CG 3.91Å; Y92-H103 AromaticContact CE1-NE2 3.62Å; E99-H103 PolarHBondContact O-CD2 3.49Å; E99-H103 PolarHBondContact O-N 3.35Å; E99-H103 IonicContact OE1-CD2 2.89Å; E99-H103 IonicContact OE1-CE1 2.96Å; E99-H103 IonicContact OE1-NE2 3.33Å; E99-H103 PolarHBondContact OE1-NE2 3.13Å; V100-H103 PolarHBondContact O-N 2.92Å; H103-R107 VanDerWaalsContact O-CB 3.31Å; H103-R107 WeakPolarHBondContact O-CB 3.28Å; H103-R107 PolarHBondContact O-N 3.5Å
104L98.5Very high97.6Very high0 Ų030.2 Ų30.20%016%0.158CC..Hα-helixtrans-62.7-45.2174.4-74.3175.1000111.4L84 F88 F90 V100 N106 R107 G108 T113 M116 L117L84-L104 HydrophobicContact CD1-CD1 4.07Å; F88-L104 HydrophobicContact CD2-CD2 4.27Å; F88-L104 HydrophobicContact CE2-CD2 4.09Å; F90-L104 HydrophobicContact CE2-CD2 4.12Å; F90-L104 HydrophobicContact CE2-CG 4.33Å; F90-L104 HydrophobicContact CZ-CD2 4.21Å; V100-L104 HydrophobicContact CG2-CD1 4.04Å; V100-L104 HydrophobicContact CG2-CG 4.12Å; V100-L104 WeakPolarHBondContact O-CB 3.25Å; V100-L104 WeakPolarHBondContact O-CG 3.27Å; V100-L104 PolarHBondContact O-N 3.42Å; L104-N106 PolarHBondContact O-N 3.04Å; L104-R107 WeakPolarHBondContact O-CB 3.47Å; L104-R107 PolarHBondContact O-N 2.88Å; L104-R107 VanDerWaalsContact O-N 3.09Å; L104-G108 PolarHBondContact O-N 2.8Å; L104-T113 HydrophobicContact CB-CG2 3.92Å; L104-T113 WeakPolarHBondContact CB-OG1 3.47Å; L104-T113 HydrophobicContact CD1-CG2 4.33Å; L104-M116 HydrophobicContact CD1-CB 4.02Å; L104-M116 HydrophobicContact CD2-CB 4.45Å; L104-L117 HydrophobicContact CD1-CD2 3.82Å
105Y98.8Very high97.5Very high20 Ų2030.7 Ų30.78%0.07816%0.161CC..Hα-helixtrans-61.6-47.4-180173.2-98000111.3L70 I101 R107 G108 G109 I110 T113 L125 D127 F134L70-Y105 HydrophobicContact CD1-CD1 3.84Å; L70-Y105 HydrophobicContact CD1-CE1 4.37Å; L70-Y105 HydrophobicContact CD2-CD1 3.95Å; L70-Y105 HydrophobicContact CD2-CE1 3.68Å; I101-Y105 WeakPolarHBondContact O-CB 3.4Å; I101-Y105 PolarHBondContact O-N 3.26Å; Y105-R107 PolarHBondContact O-N 2.72Å; Y105-G108 PolarHBondContact O-N 3.39Å; Y105-G109 WeakPolarHBondContact O-CA 3.33Å; Y105-G109 PolarHBondContact O-N 3.06Å; Y105-I110 HydrophobicContact CD2-CB 4.33Å; Y105-I110 HydrophobicContact CD2-CD1 4.47Å; Y105-I110 HydrophobicContact CE2-CB 4.35Å; Y105-T113 WeakPolarHBondContact CA-OG1 3.33Å; Y105-T113 PolarHBondContact N-OG1 3.08Å; Y105-L125 HydrophobicContact CD1-CD2 3.89Å; Y105-L125 HydrophobicContact CD2-CD2 3.56Å; Y105-L125 HydrophobicContact CE1-CD2 4.35Å; Y105-L125 HydrophobicContact CE2-CD2 4.05Å; Y105-L125 HydrophobicContact CG-CD2 3.48Å; Y105-L125 VanDerWaalsContact CG-CD2 3.48Å; Y105-D127 HydrophobicContact CE1-CB 4.17Å; Y105-D127 WeakPolarHBondContact CE1-OD2 3.42Å; Y105-D127 PolarHBondContact OH-OD2 2.86Å; Y105-D127 VanDerWaalsContact OH-OD2 3.08Å; Y105-F134 HydrophobicContact CD2-CE2 4.49Å; Y105-F134 AromaticContact CE2-CD2 3.97Å; Y105-F134 HydrophobicContact CE2-CD2 3.97Å; Y105-F134 HydrophobicContact CE2-CE1 4.28Å; Y105-F134 AromaticContact CE2-CE2 3.41Å; Y105-F134 HydrophobicContact CE2-CE2 3.41Å; Y105-F134 VanDerWaalsContact CE2-CE2 3.41Å; Y105-F134 AromaticContact CE2-CZ 3.57Å; Y105-F134 HydrophobicContact CE2-CZ 3.57Å; Y105-F134 AromaticContact CZ-CE2 3.47Å; Y105-F134 VanDerWaalsContact CZ-CE2 3.47Å; Y105-F134 AromaticContact CZ-CZ 3.84Å; Y105-F134 WeakPolarHBondContact OH-CE2 3.34Å; Y105-F134 VanDerWaalsContact OH-CZ 3.29Å; Y105-F134 WeakPolarHBondContact OH-CZ 3.24Å
106N98.3Very high97.4Very high73 Ų7325.8 Ų25.839%0.3914%0.136SC..Hα-helixtrans-64.8-27.1177.5-172.387.1000112.5F67 Y69 L102 L104F67-N106 HydrophobicContact CD1-CB 4.01Å; F67-N106 HydrophobicContact CE1-CB 3.62Å; F67-N106 WeakPolarHBondContact CE1-ND2 3.26Å; F67-N106 HydrophobicContact CZ-CB 3.9Å; Y69-N106 PolarHBondContact OH-OD1 3.21Å; L102-N106 WeakPolarHBondContact O-CB 3.49Å; L102-N106 PolarHBondContact O-N 3.02Å; L104-N106 PolarHBondContact O-N 3.04Å
107R97.3Very high97.4Very high139 Ų13925.7 Ų25.753%0.52514%0.135SC..Hα-helixtrans-77-42.1179.6180-178.5176.499.83.4112.7H103 L104 Y105H103-R107 VanDerWaalsContact O-CB 3.31Å; H103-R107 WeakPolarHBondContact O-CB 3.28Å; H103-R107 PolarHBondContact O-N 3.5Å; L104-R107 WeakPolarHBondContact O-CB 3.47Å; L104-R107 PolarHBondContact O-N 2.88Å; L104-R107 VanDerWaalsContact O-N 3.09Å; Y105-R107 PolarHBondContact O-N 2.72Å
108G96Very high97.4Very high36 Ų3625.9 Ų25.937%0.37114%0.136SC..Hα-helixtrans-153.919.9-168.900000116.1L104 Y105 Q112L104-G108 PolarHBondContact O-N 2.8Å; Y105-G108 PolarHBondContact O-N 3.39Å; G108-Q112 VanDerWaalsContact CA-OE1 3.3Å; G108-Q112 WeakPolarHBondContact O-CB 3.36Å
109G98.1Very high97.3Very high25 Ų2525.9 Ų25.926%0.25814%0.136SC..Hα-helixtrans76-174175.200000114Y105 T113Y105-G109 WeakPolarHBondContact O-CA 3.33Å; Y105-G109 PolarHBondContact O-N 3.06Å; G109-T113 WeakPolarHBondContact O-CB 2.89Å; G109-T113 PolarHBondContact O-N 2.84Å; G109-T113 VanDerWaalsContact O-N 3.16Å; G109-T113 PolarHBondContact O-OG1 3.04Å
110I98.1Very high97.3Very high14 Ų1426.2 Ų26.27%0.07214%0.138CC..Hα-helixtrans-72-37-168.6-167.763.2000113.2Y105 T113 A114 F123 F134 Y185 V187Y105-I110 HydrophobicContact CD2-CB 4.33Å; Y105-I110 HydrophobicContact CD2-CD1 4.47Å; Y105-I110 HydrophobicContact CE2-CB 4.35Å; I110-T113 WeakPolarHBondContact O-CB 3.38Å; I110-T113 PolarHBondContact O-N 3.26Å; I110-A114 WeakPolarHBondContact O-CB 3.37Å; I110-A114 PolarHBondContact O-N 2.97Å; I110-F123 HydrophobicContact CD1-CE2 3.8Å; I110-F123 HydrophobicContact CD1-CZ 3.7Å; I110-F134 HydrophobicContact CB-CD1 3.65Å; I110-F134 HydrophobicContact CB-CE1 3.83Å; I110-F134 HydrophobicContact CB-CG 4.29Å; I110-F134 HydrophobicContact CD1-CB 3.76Å; I110-F134 HydrophobicContact CD1-CD1 4.1Å; I110-F134 HydrophobicContact CD1-CG 3.94Å; I110-F134 HydrophobicContact CG1-CB 4.06Å; I110-F134 HydrophobicContact CG1-CD1 3.62Å; I110-F134 HydrophobicContact CG1-CE1 4.32Å; I110-F134 HydrophobicContact CG1-CG 3.99Å; I110-F134 HydrophobicContact CG2-CD1 3.8Å; I110-F134 HydrophobicContact CG2-CE1 3.74Å; I110-Y185 HydrophobicContact CG1-CD2 3.89Å; I110-Y185 HydrophobicContact CG1-CE2 4.46Å; I110-Y185 HydrophobicContact CG1-CG 4.06Å; I110-Y185 HydrophobicContact CG2-CD2 3.79Å; I110-Y185 HydrophobicContact CG2-CE2 3.53Å; I110-V187 HydrophobicContact CG2-CG2 4.13Å
111E95.7Very high97.3Very high120 Ų12026.2 Ų26.256%0.56114%0.138SC*.Hα-helixtrans-64.1-52.9-179.2-175.5177.9-146.600110.9T113 A114 C115 Y185E111-T113 PolarHBondContact O-N 2.84Å; E111-A114 PolarHBondContact O-N 3.25Å; E111-C115 PolarHBondContact O-N 2.92Å; E111-C115 VanDerWaalsContact O-N 3.14Å; E111-C115 PolarHBondContact O-SG 2.62Å; E111-C115 VanDerWaalsContact O-SG 3.36Å; E111-Y185 HydrophobicContact CB-CE1 4.22Å; E111-Y185 HydrophobicContact CG-CE1 4.33Å
112Q93.8Very high97.3Very high73 Ų7326.2 Ų26.234%0.34114%0.138SC..Hα-helixtrans-58.6-37.8175.4-177.2170.516.400111G108 M116G108-Q112 VanDerWaalsContact CA-OE1 3.3Å; G108-Q112 WeakPolarHBondContact O-CB 3.36Å; Q112-M116 HydrophobicContact CG-CG 4.13Å; Q112-M116 VanDerWaalsContact O-CB 3.26Å; Q112-M116 WeakPolarHBondContact O-CB 3.48Å; Q112-M116 WeakPolarHBondContact O-CG 3.38Å; Q112-M116 PolarHBondContact O-N 3.14Å
113T97.4Very high97.3Very high0 Ų026.2 Ų26.20%014%0.138CC..Hα-helixtrans-61.9-57.1177.5-58.50000110.9I101 L104 Y105 G109 I110 E111 C115 M116 L117I101-T113 HydrophobicContact CB-CG2 4.49Å; I101-T113 HydrophobicContact CG2-CG2 3.95Å; L104-T113 HydrophobicContact CB-CG2 3.92Å; L104-T113 WeakPolarHBondContact CB-OG1 3.47Å; L104-T113 HydrophobicContact CD1-CG2 4.33Å; Y105-T113 WeakPolarHBondContact CA-OG1 3.33Å; Y105-T113 PolarHBondContact N-OG1 3.08Å; G109-T113 WeakPolarHBondContact O-CB 2.89Å; G109-T113 PolarHBondContact O-N 2.84Å; G109-T113 VanDerWaalsContact O-N 3.16Å; G109-T113 PolarHBondContact O-OG1 3.04Å; I110-T113 WeakPolarHBondContact O-CB 3.38Å; I110-T113 PolarHBondContact O-N 3.26Å; E111-T113 PolarHBondContact O-N 2.84Å; T113-C115 VanDerWaalsContact C-N 3.3Å; T113-C115 PolarHBondContact O-N 3.32Å; T113-M116 PolarHBondContact O-N 3.24Å; T113-M116 VanDerWaalsContact O-N 3.07Å; T113-L117 HydrophobicContact CG2-CD1 4.48Å; T113-L117 WeakPolarHBondContact O-CG 3.46Å
114A95.3Very high97.3Very high2 Ų226 Ų262%0.01714%0.138CC..Hα-helixtrans-57.4-41.5-175.300000112.5I110 E111 M116 Y185 F204I110-A114 WeakPolarHBondContact O-CB 3.37Å; I110-A114 PolarHBondContact O-N 2.97Å; E111-A114 PolarHBondContact O-N 3.25Å; A114-M116 VanDerWaalsContact C-N 3.3Å; A114-M116 PolarHBondContact O-N 3.45Å; A114-Y185 HydrophobicContact CB-CD1 3.9Å; A114-F204 HydrophobicContact CB-CB 4.1Å; A114-F204 HydrophobicContact CB-CD1 3.82Å; A114-F204 HydrophobicContact CB-CD2 3.95Å; A114-F204 HydrophobicContact CB-CE1 4.2Å; A114-F204 HydrophobicContact CB-CE2 4.34Å; A114-F204 HydrophobicContact CB-CG 3.69Å; A114-F204 HydrophobicContact CB-CZ 4.46Å; A114-F204 WeakPolarHBondContact O-CE2 3.3Å
115C94.2Very high97.4Very high21 Ų2126 Ų2614%0.14214%0.138CC..Hα-helixtrans-72.8-18.1-179.5-61.80000114.6E111 T113 F204 L212E111-C115 PolarHBondContact O-N 2.92Å; E111-C115 VanDerWaalsContact O-N 3.14Å; E111-C115 PolarHBondContact O-SG 2.62Å; E111-C115 VanDerWaalsContact O-SG 3.36Å; T113-C115 VanDerWaalsContact C-N 3.3Å; T113-C115 PolarHBondContact O-N 3.32Å; C115-F204 PolarHBondContact SG-O 3.42Å; C115-F204 VanDerWaalsContact SG-O 3.4Å; C115-L212 HydrophobicContact CB-CB 4.48Å; C115-L212 HydrophobicContact CB-CD1 3.87Å; C115-L212 HydrophobicContact CB-CG 4.48Å
116M96.4Very high97.4Very high8 Ų825.1 Ų25.14%0.03913%0.134CC..Hα-helixtrans-96.1-8.3-174.1-72.9-70.3-58.200114N80 L84 F88 L104 Q112 T113 A114 D118 H213 Y216N80-M116 PolarHBondContact ND2-O 3.46Å; L84-M116 HydrophobicContact CD2-CE 3.4Å; L84-M116 VanDerWaalsContact CD2-CE 3.4Å; F88-M116 HydrophobicContact CE2-CE 3.88Å; F88-M116 HydrophobicContact CZ-CE 3.96Å; L104-M116 HydrophobicContact CD1-CB 4.02Å; L104-M116 HydrophobicContact CD2-CB 4.45Å; Q112-M116 HydrophobicContact CG-CG 4.13Å; Q112-M116 VanDerWaalsContact O-CB 3.26Å; Q112-M116 WeakPolarHBondContact O-CB 3.48Å; Q112-M116 WeakPolarHBondContact O-CG 3.38Å; Q112-M116 PolarHBondContact O-N 3.14Å; T113-M116 PolarHBondContact O-N 3.24Å; T113-M116 VanDerWaalsContact O-N 3.07Å; A114-M116 VanDerWaalsContact C-N 3.3Å; A114-M116 PolarHBondContact O-N 3.45Å; M116-D118 PolarHBondContact O-N 3.34Å; M116-H213 VanDerWaalsContact O-CB 3.31Å; M116-H213 WeakPolarHBondContact O-CB 3.49Å; M116-Y216 HydrophobicContact CE-CD2 3.38Å; M116-Y216 HydrophobicContact CE-CE2 3.12Å; M116-Y216 HydrophobicContact CE-CG 4.3Å; M116-Y216 HydrophobicContact SD-CD2 4.18Å; M116-Y216 HydrophobicContact SD-CE2 3.65Å
117L97.3Very high97.4Very high3 Ų321.7 Ų21.72%0.01612%0.116CC..  trans-83.1111.9-177.7-59.6177.9000110.9I78 V100 I101 L104 T113 G119 F121 F123I78-L117 HydrophobicContact CD1-CB 4.31Å; I78-L117 HydrophobicContact CD1-CD1 4.16Å; I78-L117 HydrophobicContact CD1-CD2 4.23Å; I78-L117 HydrophobicContact CD1-CG 4.44Å; I78-L117 HydrophobicContact CG1-CD2 4.4Å; I78-L117 HydrophobicContact CG2-CB 4.47Å; I78-L117 HydrophobicContact CG2-CD2 3.78Å; V100-L117 HydrophobicContact CG1-CD2 4.15Å; I101-L117 HydrophobicContact CD1-CD1 4.26Å; I101-L117 HydrophobicContact CG1-CD1 4.07Å; I101-L117 HydrophobicContact CG1-CD2 4.01Å; L104-L117 HydrophobicContact CD1-CD2 3.82Å; T113-L117 HydrophobicContact CG2-CD1 4.48Å; T113-L117 WeakPolarHBondContact O-CG 3.46Å; L117-G119 PolarHBondContact O-N 3.07Å; L117-F121 HydrophobicContact CB-CD1 4.17Å; L117-F121 HydrophobicContact CB-CE1 3.51Å; L117-F121 HydrophobicContact CB-CZ 4.11Å; L117-F121 HydrophobicContact CD1-CD1 3.98Å; L117-F121 HydrophobicContact CD1-CD2 4.41Å; L117-F121 HydrophobicContact CD1-CE1 3.65Å; L117-F121 HydrophobicContact CD1-CE2 4.1Å; L117-F121 HydrophobicContact CD1-CG 4.36Å; L117-F121 HydrophobicContact CD1-CZ 3.7Å; L117-F121 HydrophobicContact CG-CE1 4.21Å; L117-F121 HydrophobicContact CG-CZ 4.49Å; L117-F123 HydrophobicContact CD1-CE1 4.48Å
118D97.6Very high97.4Very high4 Ų417 Ų172%0.02110%0.102CC..  trans-89.493.3165.3-170.717.9000109I78 Y79 N80 M116 H213 K245 H423I78-D118 CarbonylContact C-O 3.35Å; Y79-D118 WeakPolarHBondContact CB-O 3.41Å; Y79-D118 PolarHBondContact N-O 3.23Å; N80-D118 HydrophobicContact CB-CB 3.73Å; N80-D118 VanDerWaalsContact CG-CB 3.42Å; N80-D118 PolarHBondContact ND2-N 3Å; N80-D118 PolarHBondContact OD1-N 3.37Å; N80-D118 VanDerWaalsContact OD1-N 3.11Å; M116-D118 PolarHBondContact O-N 3.34Å; D118-H213 VanDerWaalsContact CB-CE1 3.47Å; D118-H213 WeakPolarHBondContact CB-CE1 3.49Å; D118-H213 WeakPolarHBondContact CB-ND1 3.33Å; D118-H213 IonicContact OD1-CE1 3.55Å; D118-H213 PolarHBondContact OD1-CE1 2.67Å; D118-H213 VanDerWaalsContact OD1-CE1 3.32Å; D118-H213 IonicContact OD1-NE2 2.69Å; D118-K245 IonicContact OD1-NZ 3.81Å; D118-K245 VanDerWaalsContact OD2-CD 3.28Å; D118-K245 WeakPolarHBondContact OD2-CD 3.38Å; D118-K245 WeakPolarHBondContact OD2-CE 3.33Å; D118-K245 IonicContact OD2-NZ 2.68Å; D118-K245 PolarHBondContact OD2-NZ 3.43Å; D118-H423 IonicContact OD1-ND1 3.89Å; D118-H423 PolarHBondContact OD1-ND1 2.93Å
119G97.3Very high97.5Very high1 Ų118.3 Ų18.31%0.0111%0.11CC..EExtended strand (participates in β ladder)trans-179.4-178.9-169.800000113.8E77 L117 H423E77-G119 WeakPolarHBondContact O-CA 3.33Å; L117-G119 PolarHBondContact O-N 3.07Å; G119-H423 PolarHBondContact O-CE1 3.15Å
120V98.7Very high97.5Very high7 Ų722.1 Ų22.14%0.04212%0.124CC..EExtended strand (participates in β ladder)trans-117.2132.3171.1-63.70000107.5G76 E77 V142 R143G76-V120 CarbonylContact C-O 3.55Å; G76-V120 WeakPolarHBondContact CA-O 3.46Å; E77-V120 HydrophobicContact CB-CG2 4.49Å; E77-V120 PolarHBondContact N-O 2.89Å; E77-V120 PolarHBondContact O-N 3.13Å; E77-V120 VanDerWaalsContact O-N 3.08Å; V120-V142 HydrophobicContact CB-CB 3.88Å; V120-V142 HydrophobicContact CB-CG1 3.99Å; V120-V142 HydrophobicContact CG1-CB 3.61Å; V120-V142 HydrophobicContact CG1-CG1 3.76Å; V120-V142 HydrophobicContact CG1-CG2 3.83Å; V120-V142 HydrophobicContact CG2-CG1 4.38Å; V120-R143 HydrophobicContact CB-CG 4.07Å; V120-R143 HydrophobicContact CG2-CG 4.1Å
121F98.8Very high97.5Very high1 Ų127.8 Ų27.80%0.00415%0.145CC..EExtended strand (participates in β ladder)trans-163.7146.7-170.257.4-95.6000112.6N75 I78 L117 F123 R137 D138 F204N75-F121 CarbonylContact O-C 3.52Å; N75-F121 WeakPolarHBondContact O-CA 3.43Å; I78-F121 HydrophobicContact CD1-CB 4.09Å; I78-F121 HydrophobicContact CD1-CD1 3.74Å; I78-F121 HydrophobicContact CD1-CG 4.21Å; L117-F121 HydrophobicContact CB-CD1 4.17Å; L117-F121 HydrophobicContact CB-CE1 3.51Å; L117-F121 HydrophobicContact CB-CZ 4.11Å; L117-F121 HydrophobicContact CD1-CD1 3.98Å; L117-F121 HydrophobicContact CD1-CD2 4.41Å; L117-F121 HydrophobicContact CD1-CE1 3.65Å; L117-F121 HydrophobicContact CD1-CE2 4.1Å; L117-F121 HydrophobicContact CD1-CG 4.36Å; L117-F121 HydrophobicContact CD1-CZ 3.7Å; L117-F121 HydrophobicContact CG-CE1 4.21Å; L117-F121 HydrophobicContact CG-CZ 4.49Å; F121-F123 AromaticContact CD2-CD1 3.57Å; F121-F123 HydrophobicContact CD2-CD1 3.57Å; F121-F123 AromaticContact CD2-CE1 3.87Å; F121-F123 HydrophobicContact CD2-CE1 3.87Å; F121-F123 AromaticContact CE2-CD1 3.93Å; F121-F123 HydrophobicContact CE2-CD1 3.93Å; F121-F123 AromaticContact CE2-CE1 3.71Å; F121-F123 HydrophobicContact CE2-CE1 3.71Å; F121-F123 HydrophobicContact CG-CD1 4.48Å; F121-R137 CarbonylContact O-C 3.52Å; F121-R137 WeakPolarHBondContact O-CA 3.18Å; F121-D138 HydrophobicContact CD1-CB 4Å; F121-D138 HydrophobicContact CD2-CB 4.45Å; F121-D138 HydrophobicContact CE1-CB 4.03Å; F121-D138 HydrophobicContact CE2-CB 4.49Å; F121-D138 HydrophobicContact CG-CB 4.21Å; F121-D138 HydrophobicContact CZ-CB 4.3Å; F121-D138 PolarHBondContact N-OD2 3.32Å; F121-D138 PolarHBondContact O-N 2.96Å; F121-F204 HydrophobicContact CE2-CZ 4.41Å; F121-F204 AromaticContact CZ-CZ 3.93Å; F121-F204 HydrophobicContact CZ-CZ 3.93Å
122A98.9Very high97.6Very high0 Ų024.5 Ų24.50%013%0.129CC..EExtended strand (participates in β ladder)trans-127126.5155.300000106.7I4 Y74 N75 G136 R143 P144 L145I4-A122 HydrophobicContact CD1-CB 4.27Å; I4-A122 WeakPolarHBondContact CD1-O 3.48Å; Y74-A122 CarbonylContact C-O 3.6Å; Y74-A122 WeakPolarHBondContact CA-O 3.33Å; Y74-A122 WeakPolarHBondContact CB-O 3.46Å; N75-A122 PolarHBondContact N-O 3.44Å; N75-A122 PolarHBondContact O-N 3.11Å; A122-G136 CarbonylContact C-O 3.58Å; A122-G136 WeakPolarHBondContact CA-O 3.22Å; A122-R143 HydrophobicContact CB-CB 4.14Å; A122-P144 VanDerWaalsContact CB-O 3.3Å; A122-P144 WeakPolarHBondContact CB-O 3.43Å; A122-L145 HydrophobicContact CB-CB 3.87Å; A122-L145 HydrophobicContact CB-CD1 4.2Å; A122-L145 HydrophobicContact CB-CD2 4.39Å; A122-L145 HydrophobicContact CB-CG 4.39Å
123F98.9Very high97.9Very high0 Ų021 Ų210%011%0.112CC..EExtended strand (participates in β ladder)trans-132.4156.4-178.571.1-107000113.6L72 C73 I101 I110 L117 F121 L125 F134 L135 G136L72-F123 HydrophobicContact CD1-CB 3.98Å; C73-F123 CarbonylContact O-C 3.6Å; C73-F123 VanDerWaalsContact O-CA 3.28Å; C73-F123 WeakPolarHBondContact O-CA 3.5Å; I101-F123 HydrophobicContact CD1-CD1 4.45Å; I110-F123 HydrophobicContact CD1-CE2 3.8Å; I110-F123 HydrophobicContact CD1-CZ 3.7Å; L117-F123 HydrophobicContact CD1-CE1 4.48Å; F121-F123 AromaticContact CD2-CD1 3.57Å; F121-F123 HydrophobicContact CD2-CD1 3.57Å; F121-F123 AromaticContact CD2-CE1 3.87Å; F121-F123 HydrophobicContact CD2-CE1 3.87Å; F121-F123 AromaticContact CE2-CD1 3.93Å; F121-F123 HydrophobicContact CE2-CD1 3.93Å; F121-F123 AromaticContact CE2-CE1 3.71Å; F121-F123 HydrophobicContact CE2-CE1 3.71Å; F121-F123 HydrophobicContact CG-CD1 4.48Å; F123-L125 HydrophobicContact CD2-CB 4.23Å; F123-L125 HydrophobicContact CE2-CB 4.42Å; F123-F134 HydrophobicContact CE2-CB 4.34Å; F123-L135 WeakPolarHBondContact O-CA 3.38Å; F123-G136 PolarHBondContact N-O 2.6Å; F123-G136 PolarHBondContact O-N 3.49Å; F123-G136 VanDerWaalsContact O-N 3.12Å
124I98.9Very high98Very high0 Ų021.5 Ų21.50%011%0.114CC..EExtended strand (participates in β ladder)trans-127.2116.5169.1-53.8159.3000106I4 A6 F8 F45 C73 V133 F134 L135 V157I4-I124 HydrophobicContact CD1-CD1 3.97Å; I4-I124 HydrophobicContact CD1-CG1 4.09Å; I4-I124 HydrophobicContact CG1-CD1 4.43Å; A6-I124 HydrophobicContact CB-CD1 3.72Å; A6-I124 HydrophobicContact CB-CG2 4.39Å; F8-I124 HydrophobicContact CE2-CG2 3.95Å; F8-I124 HydrophobicContact CZ-CG2 3.87Å; F45-I124 HydrophobicContact CE1-CB 4.22Å; F45-I124 HydrophobicContact CE1-CG2 3.74Å; F45-I124 HydrophobicContact CZ-CG2 4.39Å; C73-I124 PolarHBondContact N-O 2.89Å; C73-I124 PolarHBondContact O-N 2.81Å; I124-V133 HydrophobicContact CG2-CG1 4.41Å; I124-F134 WeakPolarHBondContact CA-O 3.42Å; I124-L135 HydrophobicContact CB-CD2 4.33Å; I124-L135 HydrophobicContact CG1-CD2 3.96Å; I124-L135 HydrophobicContact CG2-CD2 4Å; I124-V157 HydrophobicContact CD1-CB 3.77Å; I124-V157 HydrophobicContact CD1-CG1 3.66Å; I124-V157 HydrophobicContact CG1-CB 4.27Å; I124-V157 HydrophobicContact CG1-CG1 3.84Å
125L98.9Very high98.1Very high0 Ų021.4 Ų21.40%011%0.114CC..EExtended strand (participates in β ladder)trans-116.6122.7177.4173.667.4000109.2L70 W71 L72 L102 Y105 F123 V133 F134L70-L125 HydrophobicContact CB-CD1 4.49Å; W71-L125 WeakPolarHBondContact O-CA 3.28Å; L72-L125 HydrophobicContact CB-CD1 4.2Å; L72-L125 HydrophobicContact CD1-CB 4.33Å; L102-L125 HydrophobicContact CD2-CD1 3.74Å; Y105-L125 HydrophobicContact CD1-CD2 3.89Å; Y105-L125 HydrophobicContact CD2-CD2 3.56Å; Y105-L125 HydrophobicContact CE1-CD2 4.35Å; Y105-L125 HydrophobicContact CE2-CD2 4.05Å; Y105-L125 HydrophobicContact CG-CD2 3.48Å; Y105-L125 VanDerWaalsContact CG-CD2 3.48Å; F123-L125 HydrophobicContact CD2-CB 4.23Å; F123-L125 HydrophobicContact CE2-CB 4.42Å; L125-V133 CarbonylContact O-C 3.53Å; L125-V133 WeakPolarHBondContact O-CA 3.32Å; L125-F134 HydrophobicContact CB-CB 4.24Å; L125-F134 HydrophobicContact CB-CD2 4.38Å; L125-F134 HydrophobicContact CD2-CD2 4.07Å; L125-F134 HydrophobicContact CG-CD2 4.17Å; L125-F134 PolarHBondContact N-O 3.43Å; L125-F134 PolarHBondContact O-N 2.77Å
126L98.9Very high98.3Very high1 Ų120.4 Ų20.41%0.00511%0.107CC..EExtended strand (participates in β ladder)trans-106.6126.7173.2161.568.9000109.5F8 V37 F45 L70 W71 T128 V133 L190F8-L126 HydrophobicContact CE1-CB 4.26Å; F8-L126 HydrophobicContact CE1-CD1 4.25Å; F8-L126 HydrophobicContact CE1-CD2 4.26Å; F8-L126 HydrophobicContact CE1-CG 4.49Å; V37-L126 HydrophobicContact CB-CD2 4.3Å; V37-L126 HydrophobicContact CG1-CD2 3.8Å; V37-L126 HydrophobicContact CG2-CD2 3.56Å; F45-L126 HydrophobicContact CE2-CB 4.42Å; F45-L126 HydrophobicContact CE2-CD2 3.98Å; F45-L126 HydrophobicContact CZ-CB 3.9Å; F45-L126 HydrophobicContact CZ-CD2 4.26Å; L70-L126 WeakPolarHBondContact CA-O 3.35Å; W71-L126 HydrophobicContact CB-CB 4.17Å; W71-L126 HydrophobicContact CB-CD2 4.39Å; W71-L126 HydrophobicContact CG-CD2 4.24Å; W71-L126 PolarHBondContact N-O 3.24Å; W71-L126 PolarHBondContact O-N 2.63Å; L126-T128 HydrophobicContact CD1-CG2 4.07Å; L126-T128 HydrophobicContact CD2-CG2 3.92Å; L126-T128 HydrophobicContact CG-CG2 3.94Å; L126-V133 HydrophobicContact CD1-CG2 3.99Å; L126-L190 HydrophobicContact CD1-CD2 3.74Å
127D98.6Very high98.5Very high1 Ų120.2 Ų20.21%0.00511%0.106CC..EExtended strand (participates in β ladder)trans-111106.3167.4-174.7-21.8000109.8Y69 L70 Y105 A129 N130 R131 K132 F134Y69-D127 WeakPolarHBondContact CD2-OD1 3.29Å; L70-D127 HydrophobicContact CD2-CB 3.63Å; Y105-D127 HydrophobicContact CE1-CB 4.17Å; Y105-D127 WeakPolarHBondContact CE1-OD2 3.42Å; Y105-D127 PolarHBondContact OH-OD2 2.86Å; Y105-D127 VanDerWaalsContact OH-OD2 3.08Å; D127-A129 WeakPolarHBondContact OD1-CA 3.19Å; D127-A129 WeakPolarHBondContact OD1-CB 3.28Å; D127-A129 PolarHBondContact OD1-N 2.97Å; D127-N130 PolarHBondContact OD1-N 3Å; D127-N130 PolarHBondContact OD2-ND2 2.61Å; D127-R131 CarbonylContact O-C 3.51Å; D127-R131 VanDerWaalsContact O-CA 3.26Å; D127-R131 WeakPolarHBondContact O-CA 3.44Å; D127-R131 PolarHBondContact O-N 3.38Å; D127-K132 PolarHBondContact N-O 2.96Å; D127-K132 PolarHBondContact O-N 3.27Å; D127-F134 HydrophobicContact CB-CE2 4.39Å
128T98.3Very high98.5Very high39 Ų3920.1 Ų20.124%0.23911%0.105CC..THydrogen-bonded Turntrans-77.6-21.7179.254.90000113.8V37 F40 Y69 L126V37-T128 HydrophobicContact CG1-CG2 3.92Å; F40-T128 HydrophobicContact CD2-CG2 4.39Å; F40-T128 HydrophobicContact CE2-CG2 4.43Å; Y69-T128 WeakPolarHBondContact CA-OG1 3.47Å; Y69-T128 WeakPolarHBondContact CB-OG1 3.26Å; Y69-T128 PolarHBondContact O-N 2.94Å; Y69-T128 PolarHBondContact O-OG1 3.46Å; L126-T128 HydrophobicContact CD1-CG2 4.07Å; L126-T128 HydrophobicContact CD2-CG2 3.92Å; L126-T128 HydrophobicContact CG-CG2 3.94Å
129A97.6Very high98.5Very high65 Ų6520 Ų2054%0.53711%0.105SC..THydrogen-bonded Turntrans-76-46178.600000110.6Y69 D127 R131Y69-A129 HydrophobicContact CD1-CB 4.27Å; Y69-A129 HydrophobicContact CD2-CB 3.79Å; Y69-A129 HydrophobicContact CE2-CB 4.46Å; Y69-A129 HydrophobicContact CG-CB 3.69Å; D127-A129 WeakPolarHBondContact OD1-CA 3.19Å; D127-A129 WeakPolarHBondContact OD1-CB 3.28Å; D127-A129 PolarHBondContact OD1-N 2.97Å; A129-R131 VanDerWaalsContact C-N 3.34Å
130N98Very high98.5Very high104 Ų10420 Ų2056%0.55611%0.105SC*.THydrogen-bonded Turntrans-87.7-4.9177.3-65.7-50.7000113.4D127 K132D127-N130 PolarHBondContact OD1-N 3Å; D127-N130 PolarHBondContact OD2-ND2 2.61Å; N130-K132 HydrophobicContact CB-CG 4.3Å
131R98.3Very high98.5Very high133 Ų13319.8 Ų19.850%0.50210%0.103SC..THydrogen-bonded Turntrans53.856.6-177-63.8-170.9-63.9-169.4-0.6111.9D127 A129 L190D127-R131 CarbonylContact O-C 3.51Å; D127-R131 VanDerWaalsContact O-CA 3.26Å; D127-R131 WeakPolarHBondContact O-CA 3.44Å; D127-R131 PolarHBondContact O-N 3.38Å; A129-R131 VanDerWaalsContact C-N 3.34Å; R131-L190 HydrophobicContact CB-CB 4.13Å; R131-L190 WeakPolarHBondContact CB-O 3.49Å; R131-L190 PolarHBondContact O-N 3.06Å
132K98.6Very high98.5Very high51 Ų5119.8 Ų19.822%0.22210%0.103CC..EExtended strand (participates in β ladder)trans-129.5145179.3-64.7-67.3-171.4168.90111.3D127 N130 F134 V187 L188 D189D127-K132 PolarHBondContact N-O 2.96Å; D127-K132 PolarHBondContact O-N 3.27Å; N130-K132 HydrophobicContact CB-CG 4.3Å; K132-F134 HydrophobicContact CB-CD2 4.29Å; K132-F134 HydrophobicContact CB-CE1 4.28Å; K132-F134 HydrophobicContact CB-CE2 3.38Å; K132-F134 HydrophobicContact CB-CZ 3.38Å; K132-F134 HydrophobicContact CG-CE2 4.34Å; K132-F134 HydrophobicContact CG-CZ 3.89Å; K132-V187 HydrophobicContact CD-CG1 4.04Å; K132-L188 CarbonylContact C-O 3.52Å; K132-L188 VanDerWaalsContact CA-O 3.3Å; K132-L188 WeakPolarHBondContact CA-O 3.26Å; K132-D189 WeakPolarHBondContact CE-OD1 3.43Å; K132-D189 IonicContact NZ-OD1 3.61Å; K132-D189 PolarHBondContact NZ-OD1 2.84Å
133V98.9Very high98.4Very high0 Ų019.8 Ų19.80%010%0.103CC..EExtended strand (participates in β ladder)trans-117.1134.5165.8-179.50000107.2F8 I124 L125 L126 L135 L155 L188 V196F8-V133 HydrophobicContact CD1-CG2 3.67Å; F8-V133 HydrophobicContact CD2-CG1 4.47Å; F8-V133 HydrophobicContact CE1-CB 4.45Å; F8-V133 HydrophobicContact CE1-CG1 4.06Å; F8-V133 HydrophobicContact CE1-CG2 3.48Å; F8-V133 VanDerWaalsContact CE1-CG2 3.48Å; F8-V133 HydrophobicContact CE2-CG1 3.89Å; F8-V133 HydrophobicContact CG-CG2 4.34Å; F8-V133 HydrophobicContact CZ-CG1 3.66Å; F8-V133 HydrophobicContact CZ-CG2 4Å; I124-V133 HydrophobicContact CG2-CG1 4.41Å; L125-V133 CarbonylContact O-C 3.53Å; L125-V133 WeakPolarHBondContact O-CA 3.32Å; L126-V133 HydrophobicContact CD1-CG2 3.99Å; V133-L135 HydrophobicContact CG1-CD2 4.39Å; V133-L155 HydrophobicContact CG1-CD2 4.27Å; V133-L188 HydrophobicContact CB-CB 4.35Å; V133-L188 PolarHBondContact N-O 2.74Å; V133-L188 PolarHBondContact O-N 3Å; V133-V196 HydrophobicContact CG2-CG1 4.06Å
134F98.9Very high98.4Very high10 Ų1019.8 Ų19.84%0.04410%0.104CC..EExtended strand (participates in β ladder)trans-121.2133.1177.3-52.2-87.9000109.8Y105 I110 F123 I124 L125 D127 K132 E186 V187Y105-F134 HydrophobicContact CD2-CE2 4.49Å; Y105-F134 AromaticContact CE2-CD2 3.97Å; Y105-F134 HydrophobicContact CE2-CD2 3.97Å; Y105-F134 HydrophobicContact CE2-CE1 4.28Å; Y105-F134 AromaticContact CE2-CE2 3.41Å; Y105-F134 HydrophobicContact CE2-CE2 3.41Å; Y105-F134 VanDerWaalsContact CE2-CE2 3.41Å; Y105-F134 AromaticContact CE2-CZ 3.57Å; Y105-F134 HydrophobicContact CE2-CZ 3.57Å; Y105-F134 AromaticContact CZ-CE2 3.47Å; Y105-F134 VanDerWaalsContact CZ-CE2 3.47Å; Y105-F134 AromaticContact CZ-CZ 3.84Å; Y105-F134 WeakPolarHBondContact OH-CE2 3.34Å; Y105-F134 VanDerWaalsContact OH-CZ 3.29Å; Y105-F134 WeakPolarHBondContact OH-CZ 3.24Å; I110-F134 HydrophobicContact CB-CD1 3.65Å; I110-F134 HydrophobicContact CB-CE1 3.83Å; I110-F134 HydrophobicContact CB-CG 4.29Å; I110-F134 HydrophobicContact CD1-CB 3.76Å; I110-F134 HydrophobicContact CD1-CD1 4.1Å; I110-F134 HydrophobicContact CD1-CG 3.94Å; I110-F134 HydrophobicContact CG1-CB 4.06Å; I110-F134 HydrophobicContact CG1-CD1 3.62Å; I110-F134 HydrophobicContact CG1-CE1 4.32Å; I110-F134 HydrophobicContact CG1-CG 3.99Å; I110-F134 HydrophobicContact CG2-CD1 3.8Å; I110-F134 HydrophobicContact CG2-CE1 3.74Å; F123-F134 HydrophobicContact CE2-CB 4.34Å; I124-F134 WeakPolarHBondContact CA-O 3.42Å; L125-F134 HydrophobicContact CB-CB 4.24Å; L125-F134 HydrophobicContact CB-CD2 4.38Å; L125-F134 HydrophobicContact CD2-CD2 4.07Å; L125-F134 HydrophobicContact CG-CD2 4.17Å; L125-F134 PolarHBondContact N-O 3.43Å; L125-F134 PolarHBondContact O-N 2.77Å; D127-F134 HydrophobicContact CB-CE2 4.39Å; K132-F134 HydrophobicContact CB-CD2 4.29Å; K132-F134 HydrophobicContact CB-CE1 4.28Å; K132-F134 HydrophobicContact CB-CE2 3.38Å; K132-F134 HydrophobicContact CB-CZ 3.38Å; K132-F134 HydrophobicContact CG-CE2 4.34Å; K132-F134 HydrophobicContact CG-CZ 3.89Å; F134-E186 VanDerWaalsContact CA-O 3.27Å; F134-E186 WeakPolarHBondContact CA-O 3.4Å; F134-V187 HydrophobicContact CD1-CB 4.36Å; F134-V187 HydrophobicContact CD1-CG1 4.25Å; F134-V187 HydrophobicContact CD1-CG2 3.95Å; F134-V187 HydrophobicContact CE1-CB 4.31Å; F134-V187 HydrophobicContact CE1-CG1 3.78Å; F134-V187 HydrophobicContact CE1-CG2 3.93Å
135L98.9Very high98.4Very high0 Ų019.8 Ų19.80%010%0.104CC..EExtended strand (participates in β ladder)trans-109.4144.4168.3-50.7-176.5000107.8F123 I124 V133 L145 K147 L155 V157 F180 Y185 E186 L188F123-L135 WeakPolarHBondContact O-CA 3.38Å; I124-L135 HydrophobicContact CB-CD2 4.33Å; I124-L135 HydrophobicContact CG1-CD2 3.96Å; I124-L135 HydrophobicContact CG2-CD2 4Å; V133-L135 HydrophobicContact CG1-CD2 4.39Å; L135-L145 HydrophobicContact CB-CD2 4.44Å; L135-K147 HydrophobicContact CD1-CD 4.29Å; L135-L155 HydrophobicContact CD1-CD1 4.47Å; L135-V157 HydrophobicContact CD1-CG2 3.97Å; L135-V157 HydrophobicContact CD2-CG1 4.23Å; L135-V157 HydrophobicContact CD2-CG2 3.86Å; L135-F180 HydrophobicContact CB-CD2 4.17Å; L135-F180 HydrophobicContact CB-CE2 3.55Å; L135-F180 HydrophobicContact CB-CZ 3.77Å; L135-F180 HydrophobicContact CD1-CD2 4.06Å; L135-F180 HydrophobicContact CD1-CE2 3.95Å; L135-F180 HydrophobicContact CG-CE2 4.37Å; L135-Y185 CarbonylContact O-C 3.6Å; L135-Y185 WeakPolarHBondContact O-CA 3.45Å; L135-Y185 VanDerWaalsContact O-CB 3.31Å; L135-Y185 WeakPolarHBondContact O-CB 3.3Å; L135-E186 HydrophobicContact CB-CB 4.3Å; L135-E186 PolarHBondContact N-O 3.4Å; L135-E186 VanDerWaalsContact N-O 3.07Å; L135-E186 PolarHBondContact O-N 3.43Å; L135-L188 HydrophobicContact CD1-CD1 4.34Å; L135-L188 HydrophobicContact CG-CD1 4.07Å
136G98.6Very high98.4Very high0 Ų020.3 Ų20.30%011%0.106CC..EExtended strand (participates in β ladder)trans-152.9145.9174.500000112.3A122 F123 H184A122-G136 CarbonylContact C-O 3.58Å; A122-G136 WeakPolarHBondContact CA-O 3.22Å; F123-G136 PolarHBondContact N-O 2.6Å; F123-G136 PolarHBondContact O-N 3.49Å; F123-G136 VanDerWaalsContact O-N 3.12Å; G136-H184 WeakPolarHBondContact CA-O 3.2Å
137R98.8Very high98.4Very high4 Ų421 Ų212%0.01511%0.109CC..EExtended strand (participates in β ladder)trans-138.6139.7-179.1-169.1177.3-176.3-170.9-7.9111F121 G141 R143 F180 G183 H184 F204F121-R137 CarbonylContact O-C 3.52Å; F121-R137 WeakPolarHBondContact O-CA 3.18Å; R137-G141 PolarHBondContact NH2-O 3.27Å; R137-R143 PolarHBondContact NE-O 3.37Å; R137-F180 HydrophobicContact CB-CD1 3.68Å; R137-F180 HydrophobicContact CB-CE1 3.95Å; R137-F180 WeakPolarHBondContact CD-O 3.47Å; R137-F180 PolarHBondContact NH1-O 3.44Å; R137-G183 PolarHBondContact O-N 3.24Å; R137-G183 VanDerWaalsContact O-N 3.14Å; R137-H184 PolarHBondContact N-O 3.44Å; R137-F204 VanDerWaalsContact O-CE1 3.3Å; R137-F204 WeakPolarHBondContact O-CE1 3.18Å; R137-F204 WeakPolarHBondContact O-CZ 3.41Å
138D98.4Very high98.2Very high1 Ų121 Ų211%0.00511%0.109CC..  trans-59.8160.9-177.768.578.1000113.4F121 Y140 G141 V142 R143 P182 G183F121-D138 HydrophobicContact CD1-CB 4Å; F121-D138 HydrophobicContact CD2-CB 4.45Å; F121-D138 HydrophobicContact CE1-CB 4.03Å; F121-D138 HydrophobicContact CE2-CB 4.49Å; F121-D138 HydrophobicContact CG-CB 4.21Å; F121-D138 HydrophobicContact CZ-CB 4.3Å; F121-D138 PolarHBondContact N-OD2 3.32Å; F121-D138 PolarHBondContact O-N 2.96Å; D138-Y140 VanDerWaalsContact C-N 3.33Å; D138-Y140 PolarHBondContact O-N 3.45Å; D138-Y140 PolarHBondContact OD1-N 3.38Å; D138-G141 PolarHBondContact O-N 2.9Å; D138-G141 VanDerWaalsContact O-N 3.08Å; D138-G141 WeakPolarHBondContact OD1-CA 3.32Å; D138-G141 PolarHBondContact OD1-N 3.36Å; D138-V142 PolarHBondContact OD1-N 3.27Å; D138-V142 PolarHBondContact OD2-N 3.09Å; D138-R143 PolarHBondContact OD2-N 3.11Å; D138-P182 CarbonylContact O-C 3.57Å; D138-P182 WeakPolarHBondContact O-CA 3.48Å; D138-G183 PolarHBondContact O-N 3.34Å
139T96.9Very high98.1Very high2 Ų222 Ų221%0.01211%0.112CC..THydrogen-bonded Turntrans-46.2-49.2-172.5-63.40000114.4P182 H205 Y207 H423T139-P182 WeakPolarHBondContact O-CB 3.41Å; T139-H205 WeakPolarHBondContact CG2-CD2 3.28Å; T139-H205 PolarHBondContact OG1-CD2 3.42Å; T139-Y207 HydrophobicContact CG2-CD1 3.63Å; T139-Y207 HydrophobicContact CG2-CE1 3.52Å; T139-H423 WeakPolarHBondContact CB-NE2 3.49Å; T139-H423 PolarHBondContact OG1-CD2 2.88Å; T139-H423 PolarHBondContact OG1-NE2 3.11Å
140Y97.6Very high98Very high2 Ų219.8 Ų19.81%0.0089%0.092CC..THydrogen-bonded Turntrans-101.20.9-174.2-61.6-70.3000112.6D138 V142 Y207 L394 L421 T426D138-Y140 VanDerWaalsContact C-N 3.33Å; D138-Y140 PolarHBondContact O-N 3.45Å; D138-Y140 PolarHBondContact OD1-N 3.38Å; Y140-V142 VanDerWaalsContact C-N 3.31Å; Y140-Y207 HydrophobicContact CD1-CD1 4.02Å; Y140-Y207 AromaticContact CD1-CE1 3.76Å; Y140-Y207 HydrophobicContact CD1-CE1 3.76Å; Y140-Y207 AromaticContact CE1-CD1 3.3Å; Y140-Y207 HydrophobicContact CE1-CD1 3.3Å; Y140-Y207 AromaticContact CE1-CE1 3.55Å; Y140-Y207 HydrophobicContact CE1-CE1 3.55Å; Y140-Y207 HydrophobicContact CE1-CG 4.39Å; Y140-Y207 AromaticContact CZ-CD1 3.79Å; Y140-L394 HydrophobicContact CD1-CB 4.41Å; Y140-L394 HydrophobicContact CD1-CD2 4.43Å; Y140-L394 HydrophobicContact CE1-CB 4.14Å; Y140-L394 HydrophobicContact CE1-CD1 4.49Å; Y140-L394 HydrophobicContact CE1-CD2 4.13Å; Y140-L394 HydrophobicContact CE1-CG 4.5Å; Y140-L421 HydrophobicContact CD1-CD2 4.44Å; Y140-L421 HydrophobicContact CD2-CB 3.93Å; Y140-L421 HydrophobicContact CD2-CD2 4.32Å; Y140-L421 HydrophobicContact CE2-CB 4.42Å; Y140-L421 HydrophobicContact CG-CB 4.46Å; Y140-L421 HydrophobicContact CG-CD2 4.22Å; Y140-T426 HydrophobicContact CE2-CG2 4.03Å; Y140-T426 WeakPolarHBondContact OH-CB 3.34Å; Y140-T426 PolarHBondContact OH-OG1 3.07Å
141G98.1Very high97.7Very high1 Ų123.4 Ų23.41%0.0111%0.112CC..  trans70.629.5179.400000112.7R137 D138 R143 V402R137-G141 PolarHBondContact NH2-O 3.27Å; D138-G141 PolarHBondContact O-N 2.9Å; D138-G141 VanDerWaalsContact O-N 3.08Å; D138-G141 WeakPolarHBondContact OD1-CA 3.32Å; D138-G141 PolarHBondContact OD1-N 3.36Å; G141-R143 VanDerWaalsContact C-N 3.26Å; G141-R143 PolarHBondContact O-N 2.97Å; G141-V402 WeakPolarHBondContact O-CG1 3.28Å
142V98.6Very high97.5Very high1 Ų119.8 Ų19.81%0.00610%0.102CC..  trans-57.6-40.5-178.9-179.60000111.2V120 D138 Y140 V402 V418 L421V120-V142 HydrophobicContact CB-CB 3.88Å; V120-V142 HydrophobicContact CB-CG1 3.99Å; V120-V142 HydrophobicContact CG1-CB 3.61Å; V120-V142 HydrophobicContact CG1-CG1 3.76Å; V120-V142 HydrophobicContact CG1-CG2 3.83Å; V120-V142 HydrophobicContact CG2-CG1 4.38Å; D138-V142 PolarHBondContact OD1-N 3.27Å; D138-V142 PolarHBondContact OD2-N 3.09Å; Y140-V142 VanDerWaalsContact C-N 3.31Å; V142-V402 VanDerWaalsContact CA-CG1 3.47Å; V142-V402 HydrophobicContact CB-CG1 4.48Å; V142-V418 HydrophobicContact CG1-CG2 3.81Å; V142-V418 HydrophobicContact CG2-CG2 4.07Å; V142-L421 HydrophobicContact CG2-CD1 3.87Å
143R98.8Very high97.3Very high0 Ų017.6 Ų17.60%09%0.094CC..SBendtrans-97.8133.6169.6-62.7-67-175.2-990.3109.6M1 N75 V120 A122 R137 D138 G141 E415 L416M1-R143 PolarHBondContact SD-NH1 3.19Å; N75-R143 WeakPolarHBondContact O-CB 3.46Å; N75-R143 VanDerWaalsContact O-CG 3.3Å; N75-R143 WeakPolarHBondContact O-CG 3.26Å; V120-R143 HydrophobicContact CB-CG 4.07Å; V120-R143 HydrophobicContact CG2-CG 4.1Å; A122-R143 HydrophobicContact CB-CB 4.14Å; R137-R143 PolarHBondContact NE-O 3.37Å; D138-R143 PolarHBondContact OD2-N 3.11Å; G141-R143 VanDerWaalsContact C-N 3.26Å; G141-R143 PolarHBondContact O-N 2.97Å; R143-E415 IonicContact NH2-OE2 3.04Å; R143-L416 PolarHBondContact NH1-O 3.44Å; R143-L416 VanDerWaalsContact NH1-O 3.09Å; R143-L416 PolarHBondContact NH2-O 3.19Å
144P98.7Very high97.2Very high1 Ų117.6 Ų17.61%0.0069%0.094CC..  trans-85.5151.5-17437.2-41.6000113.1A122 S159 D406 R407A122-P144 VanDerWaalsContact CB-O 3.3Å; A122-P144 WeakPolarHBondContact CB-O 3.43Å; P144-S159 CarbonylContact C-O 3.59Å; P144-S159 WeakPolarHBondContact CB-O 3.42Å; P144-S159 WeakPolarHBondContact CG-O 3.2Å; P144-D406 VanDerWaalsContact CD-CG 3.5Å; P144-D406 WeakPolarHBondContact CD-OD1 3.41Å; P144-D406 WeakPolarHBondContact CG-OD2 3.34Å; P144-R407 VanDerWaalsContact CB-CZ 3.43Å; P144-R407 VanDerWaalsContact CB-NH2 3.29Å; P144-R407 VanDerWaalsContact CG-NH1 3.3Å
145L98.8Very high97.1Very high0 Ų017.1 Ų17.10%09%0.092CC..  trans-151.2135.1173.1-165.461.6000109.2I4 A122 L135 V157 C158 F180I4-L145 HydrophobicContact CD1-CD1 3.66Å; I4-L145 HydrophobicContact CG1-CD1 4.24Å; A122-L145 HydrophobicContact CB-CB 3.87Å; A122-L145 HydrophobicContact CB-CD1 4.2Å; A122-L145 HydrophobicContact CB-CD2 4.39Å; A122-L145 HydrophobicContact CB-CG 4.39Å; L135-L145 HydrophobicContact CB-CD2 4.44Å; L145-V157 HydrophobicContact CD1-CG1 3.37Å; L145-V157 HydrophobicContact CD2-CG1 4.25Å; L145-V157 HydrophobicContact CG-CG1 3.87Å; L145-C158 CarbonylContact C-O 3.5Å; L145-F180 HydrophobicContact CB-CB 3.95Å; L145-F180 HydrophobicContact CD2-CB 4.1Å; L145-F180 HydrophobicContact CD2-CD1 4.02Å; L145-F180 HydrophobicContact CD2-CG 3.96Å; L145-F180 HydrophobicContact CG-CB 4.02Å; L145-F180 HydrophobicContact CG-CG 4.42Å; L145-F180 WeakPolarHBondContact O-CB 3.38Å; L145-F180 PolarHBondContact O-N 3.35Å
146F98.7Very high97.1Very high10 Ų1017.1 Ų17.14%0.0449%0.092CC..EExtended strand (participates in β ladder)trans-126.5152173.6-71.3-100.6000108.9V157 C158 A161 L164 V177 E178 P179F146-V157 WeakPolarHBondContact O-CA 3.21Å; F146-V157 WeakPolarHBondContact O-CG1 3.37Å; F146-C158 PolarHBondContact N-O 3.42Å; F146-C158 PolarHBondContact O-N 3.37Å; F146-A161 HydrophobicContact CD1-CB 3.73Å; F146-A161 HydrophobicContact CD2-CB 4.33Å; F146-A161 HydrophobicContact CE1-CB 3.82Å; F146-A161 HydrophobicContact CE2-CB 4.42Å; F146-A161 HydrophobicContact CG-CB 3.99Å; F146-A161 HydrophobicContact CZ-CB 4.18Å; F146-L164 HydrophobicContact CB-CD1 3.88Å; F146-V177 HydrophobicContact CB-CG1 4.14Å; F146-V177 HydrophobicContact CD1-CG1 4.03Å; F146-V177 HydrophobicContact CG-CG1 4.48Å; F146-E178 CarbonylContact C-O 3.53Å; F146-E178 VanDerWaalsContact CA-O 3.3Å; F146-E178 WeakPolarHBondContact CA-O 3.32Å; F146-P179 HydrophobicContact CD1-CB 4.21Å; F146-P179 HydrophobicContact CD1-CG 4.16Å; F146-P179 HydrophobicContact CE1-CB 3.95Å; F146-P179 HydrophobicContact CE1-CG 3.66Å; F146-P179 HydrophobicContact CZ-CB 4.47Å; F146-P179 HydrophobicContact CZ-CG 4.41Å
147K97.9Very high97.1Very high16 Ų1617.1 Ų17.17%0.079%0.092CC..EExtended strand (participates in β ladder)trans-134159.2174.770171.1-176.2179.90112.4L135 L155 G156 V157 V177 E178 F180 E186L135-K147 HydrophobicContact CD1-CD 4.29Å; K147-L155 HydrophobicContact CB-CD1 4.4Å; K147-G156 CarbonylContact C-O 3.51Å; K147-G156 VanDerWaalsContact CA-O 3.23Å; K147-G156 WeakPolarHBondContact CA-O 3.1Å; K147-V157 HydrophobicContact CB-CG2 4.35Å; K147-V177 WeakPolarHBondContact O-CA 3.45Å; K147-E178 WeakPolarHBondContact CE-OE1 3.43Å; K147-E178 HydrophobicContact CG-CG 3.96Å; K147-E178 PolarHBondContact N-O 3.18Å; K147-E178 IonicContact NZ-OE1 2.7Å; K147-E178 PolarHBondContact O-N 3.15Å; K147-F180 HydrophobicContact CD-CD2 4.22Å; K147-E186 IonicContact NZ-OE1 3.67Å; K147-E186 PolarHBondContact NZ-OE1 3.07Å; K147-E186 IonicContact NZ-OE2 2.88Å; K147-E186 PolarHBondContact NZ-OE2 2.81Å
148V95.9Very high97.1Very high1 Ų117 Ų171%0.0069%0.092CC..EExtended strand (participates in β ladder)trans-125.7127.1165.2155.90000105.7T150 F154 L155 G156 L164 P175 V177V148-T150 HydrophobicContact CG1-CG2 4.42Å; V148-F154 HydrophobicContact CG1-CD1 4.28Å; V148-F154 HydrophobicContact CG1-CE1 4.2Å; V148-L155 CarbonylContact O-C 3.54Å; V148-L155 VanDerWaalsContact O-CA 3.28Å; V148-L155 WeakPolarHBondContact O-CA 2.83Å; V148-L155 WeakPolarHBondContact O-CD1 3.07Å; V148-G156 PolarHBondContact N-O 2.99Å; V148-G156 PolarHBondContact O-N 3.4Å; V148-L164 HydrophobicContact CG2-CB 4.19Å; V148-L164 HydrophobicContact CG2-CD1 4.27Å; V148-P175 HydrophobicContact CB-CB 4.23Å; V148-P175 HydrophobicContact CG1-CB 3.28Å; V148-P175 HydrophobicContact CG1-CG 4Å; V148-P175 HydrophobicContact CG2-CB 3.93Å; V148-P175 HydrophobicContact CG2-CG 4.27Å; V148-V177 HydrophobicContact CG2-CB 4.2Å; V148-V177 HydrophobicContact CG2-CG2 3.6Å
149L95.7Very high97.1Very high60 Ų6016.9 Ų16.931%0.3149%0.091SC..EExtended strand (participates in β ladder)trans-132.3120.6170-179.863.4000108.8F154 L155 L188 V196L149-F154 WeakPolarHBondContact CA-O 3.13Å; L149-L155 HydrophobicContact CB-CD1 4.34Å; L149-L155 HydrophobicContact CD1-CB 4.16Å; L149-L155 HydrophobicContact CD1-CD1 4.31Å; L149-L188 HydrophobicContact CD2-CD2 4.44Å; L149-V196 HydrophobicContact CD1-CG2 3.84Å
150T94.8Very high97.2Very high18 Ų1816.9 Ų16.911%0.119%0.091CC..  trans-94.2162.2176.866.80000111.4V148 D152 G153 F154V148-T150 HydrophobicContact CG1-CG2 4.42Å; T150-D152 WeakPolarHBondContact CB-OD1 3.23Å; T150-D152 PolarHBondContact O-N 3.37Å; T150-D152 PolarHBondContact OG1-OD1 3.35Å; T150-G153 WeakPolarHBondContact O-CA 3.34Å; T150-G153 PolarHBondContact O-N 2.96Å; T150-F154 HydrophobicContact CG2-CB 4.34Å; T150-F154 HydrophobicContact CG2-CD1 4.03Å; T150-F154 PolarHBondContact N-O 3.38Å; T150-F154 WeakPolarHBondContact OG1-CB 3.49Å; T150-F154 PolarHBondContact OG1-N 3.22Å; T150-F154 VanDerWaalsContact OG1-N 3.07Å
151D92.6Very high97.2Very high181 Ų18116.8 Ų16.897%0.9689%0.091SC*.THydrogen-bonded Turntrans-61.5-30.3-179.7-63.1-22.3000113.2G153D151-G153 PolarHBondContact O-N 3Å
152D93.1Very high97.1Very high56 Ų5616.8 Ų16.830%0.2999%0.09SC..THydrogen-bonded Turntrans-81-0.8175.571.4-65.1000113.5T150 H169 T171 K195T150-D152 WeakPolarHBondContact CB-OD1 3.23Å; T150-D152 PolarHBondContact O-N 3.37Å; T150-D152 PolarHBondContact OG1-OD1 3.35Å; D152-H169 VanDerWaalsContact CG-NE2 3.29Å; D152-H169 IonicContact OD1-CD2 2.79Å; D152-H169 IonicContact OD1-NE2 2.82Å; D152-H169 PolarHBondContact OD1-NE2 2.98Å; D152-H169 IonicContact OD2-CD2 3.97Å; D152-H169 IonicContact OD2-CE1 3.7Å; D152-H169 PolarHBondContact OD2-CE1 3.12Å; D152-H169 IonicContact OD2-NE2 2.78Å; D152-H169 PolarHBondContact OD2-NE2 2.77Å; D152-T171 HydrophobicContact CB-CG2 4.4Å; D152-T171 PolarHBondContact OD1-OG1 3.33Å; D152-K195 WeakPolarHBondContact O-CD 3.32Å; D152-K195 IonicContact OD2-NZ 3.43Å; D152-K195 PolarHBondContact OD2-NZ 2.66Å
153G95.5Very high97Very high6 Ų616.8 Ų16.86%0.0629%0.09CC..  trans8822.3174.400000115T150 D151 K195 V196T150-G153 WeakPolarHBondContact O-CA 3.34Å; T150-G153 PolarHBondContact O-N 2.96Å; D151-G153 PolarHBondContact O-N 3Å; G153-K195 CarbonylContact O-C 3.56Å; G153-K195 WeakPolarHBondContact O-CA 3.25Å; G153-K195 WeakPolarHBondContact O-CB 3.3Å; G153-V196 WeakPolarHBondContact CA-O 3.47Å; G153-V196 PolarHBondContact O-N 2.95Å
154F95.9Very high96.8Very high0 Ų016.8 Ų16.80%09%0.09CC..  trans-75.9124165.8167.7-107.4000109.2L7 V148 L149 T150 L167 H169L7-F154 HydrophobicContact CB-CE2 4.31Å; L7-F154 HydrophobicContact CD1-CE2 4.28Å; L7-F154 HydrophobicContact CD1-CZ 4.4Å; L7-F154 HydrophobicContact CD2-CE2 4.01Å; L7-F154 HydrophobicContact CD2-CZ 3.76Å; L7-F154 HydrophobicContact CG-CE2 4.44Å; V148-F154 HydrophobicContact CG1-CD1 4.28Å; V148-F154 HydrophobicContact CG1-CE1 4.2Å; L149-F154 WeakPolarHBondContact CA-O 3.13Å; T150-F154 HydrophobicContact CG2-CB 4.34Å; T150-F154 HydrophobicContact CG2-CD1 4.03Å; T150-F154 PolarHBondContact N-O 3.38Å; T150-F154 WeakPolarHBondContact OG1-CB 3.49Å; T150-F154 PolarHBondContact OG1-N 3.22Å; T150-F154 VanDerWaalsContact OG1-N 3.07Å; F154-L167 HydrophobicContact CZ-CD1 4.28Å; F154-H169 WeakPolarHBondContact CB-NE2 3.48Å; F154-H169 HydrophobicContact CD1-CB 4.02Å; F154-H169 AromaticContact CD1-CG 3.74Å; F154-H169 HydrophobicContact CE1-CB 4.18Å; F154-H169 AromaticContact CG-CG 3.88Å; F154-H169 AromaticContact CG-ND1 3.86Å
155L97.6Very high96.4Very high0 Ų018.2 Ų18.20%010%0.099CC..EExtended strand (participates in β ladder)trans-115.6125177.8174.276.8000109.7L7 F8 V133 L135 K147 V148 L149 V157 L188 V196L7-L155 CarbonylContact C-O 3.41Å; L7-L155 VanDerWaalsContact CA-O 3.32Å; L7-L155 WeakPolarHBondContact CA-O 3.47Å; F8-L155 HydrophobicContact CB-CB 4.26Å; F8-L155 HydrophobicContact CD2-CB 4.38Å; F8-L155 HydrophobicContact CD2-CD2 3.67Å; F8-L155 HydrophobicContact CD2-CG 4.21Å; F8-L155 HydrophobicContact CE2-CD2 4.15Å; F8-L155 HydrophobicContact CG-CD2 4.4Å; F8-L155 PolarHBondContact N-O 2.8Å; F8-L155 PolarHBondContact O-N 3.01Å; V133-L155 HydrophobicContact CG1-CD2 4.27Å; L135-L155 HydrophobicContact CD1-CD1 4.47Å; K147-L155 HydrophobicContact CB-CD1 4.4Å; V148-L155 CarbonylContact O-C 3.54Å; V148-L155 VanDerWaalsContact O-CA 3.28Å; V148-L155 WeakPolarHBondContact O-CA 2.83Å; V148-L155 WeakPolarHBondContact O-CD1 3.07Å; L149-L155 HydrophobicContact CB-CD1 4.34Å; L149-L155 HydrophobicContact CD1-CB 4.16Å; L149-L155 HydrophobicContact CD1-CD1 4.31Å; L155-V157 HydrophobicContact CD1-CG2 3.84Å; L155-V157 HydrophobicContact CD2-CG2 3.94Å; L155-V157 HydrophobicContact CG-CG2 3.75Å; L155-L188 HydrophobicContact CD1-CD2 4.49Å; L155-L188 HydrophobicContact CD2-CD2 4.23Å; L155-V196 HydrophobicContact CB-CG2 3.47Å; L155-V196 VanDerWaalsContact CB-CG2 3.47Å; L155-V196 HydrophobicContact CD2-CG2 4.06Å; L155-V196 HydrophobicContact CG-CG2 4.29Å
156G97.3Very high95.8Very high0 Ų022.9 Ų22.90%012%0.124CC..EExtended strand (participates in β ladder)trans-115.5136.2165.500000110.4A6 K147 V148A6-G156 WeakPolarHBondContact O-CA 3.36Å; K147-G156 CarbonylContact C-O 3.51Å; K147-G156 VanDerWaalsContact CA-O 3.23Å; K147-G156 WeakPolarHBondContact CA-O 3.1Å; V148-G156 PolarHBondContact N-O 2.99Å; V148-G156 PolarHBondContact O-N 3.4Å
157V98.6Very high95.3Very high0 Ų022.6 Ų22.60%012%0.123CC..EExtended strand (participates in β ladder)trans-134.7136.9-179.7-172.40000109.4W5 A6 I124 L135 L145 F146 K147 L155W5-V157 CarbonylContact C-O 3.57Å; W5-V157 VanDerWaalsContact CA-O 3.28Å; W5-V157 WeakPolarHBondContact CA-O 3.49Å; A6-V157 PolarHBondContact N-O 3Å; A6-V157 PolarHBondContact O-N 2.87Å; I124-V157 HydrophobicContact CD1-CB 3.77Å; I124-V157 HydrophobicContact CD1-CG1 3.66Å; I124-V157 HydrophobicContact CG1-CB 4.27Å; I124-V157 HydrophobicContact CG1-CG1 3.84Å; L135-V157 HydrophobicContact CD1-CG2 3.97Å; L135-V157 HydrophobicContact CD2-CG1 4.23Å; L135-V157 HydrophobicContact CD2-CG2 3.86Å; L145-V157 HydrophobicContact CD1-CG1 3.37Å; L145-V157 HydrophobicContact CD2-CG1 4.25Å; L145-V157 HydrophobicContact CG-CG1 3.87Å; F146-V157 WeakPolarHBondContact O-CA 3.21Å; F146-V157 WeakPolarHBondContact O-CG1 3.37Å; K147-V157 HydrophobicContact CB-CG2 4.35Å; L155-V157 HydrophobicContact CD1-CG2 3.84Å; L155-V157 HydrophobicContact CD2-CG2 3.94Å; L155-V157 HydrophobicContact CG-CG2 3.75Å
158C98.7Very high94.6Very high0 Ų028.8 Ų28.80%015%0.15CC..EExtended strand (participates in β ladder)trans-150.6152.7-177.1-170.20000112.1I4 L145 F146 E160 L164I4-C158 CarbonylContact O-C 3.59Å; I4-C158 VanDerWaalsContact O-CA 3.28Å; I4-C158 WeakPolarHBondContact O-CA 2.96Å; L145-C158 CarbonylContact C-O 3.5Å; F146-C158 PolarHBondContact N-O 3.42Å; F146-C158 PolarHBondContact O-N 3.37Å; C158-E160 VanDerWaalsContact C-N 3.28Å; C158-E160 WeakPolarHBondContact CB-O 3.29Å; C158-E160 PolarHBondContact O-N 2.91Å; C158-E160 PolarHBondContact SG-O 2.66Å; C158-L164 HydrophobicContact CB-CD1 3.89Å; C158-L164 HydrophobicContact CB-CD2 3.65Å; C158-L164 HydrophobicContact CB-CG 3.53Å
159S98.8Very high94Very high0 Ų029 Ų290%015%0.151CC..SBendtrans-60.3-36.6170.3-63.80000113.3I4 P144I4-S159 VanDerWaalsContact CG1-OG 3.3Å; I4-S159 WeakPolarHBondContact CG1-OG 3.47Å; I4-S159 PolarHBondContact N-OG 3.48Å; I4-S159 PolarHBondContact O-N 2.97Å; P144-S159 CarbonylContact C-O 3.59Å; P144-S159 WeakPolarHBondContact CB-O 3.42Å; P144-S159 WeakPolarHBondContact CG-O 3.2Å
160E98.7Very high93.2Very high1 Ų129.9 Ų29.91%0.00516%0.162CC..SBendtrans-130.3141.2-176.3-62.9180178.700109.7I24 H26 R27 C158 K162 G163 E332I24-E160 HydrophobicContact CG2-CB 3.89Å; I24-E160 HydrophobicContact CG2-CG 4.37Å; H26-E160 IonicContact CD2-OE1 3.32Å; H26-E160 IonicContact CE1-OE2 3.55Å; H26-E160 PolarHBondContact CE1-OE2 3.34Å; H26-E160 VanDerWaalsContact NE2-CD 3.34Å; H26-E160 IonicContact NE2-OE1 3.77Å; H26-E160 PolarHBondContact NE2-OE1 3.26Å; H26-E160 IonicContact NE2-OE2 3.34Å; H26-E160 PolarHBondContact NE2-OE2 2.71Å; R27-E160 VanDerWaalsContact CD-OE1 3.26Å; R27-E160 WeakPolarHBondContact CD-OE1 3.46Å; R27-E160 IonicContact CZ-OE1 2.68Å; R27-E160 IonicContact NE-OE1 2.77Å; R27-E160 IonicContact NH1-OE1 3.94Å; R27-E160 PolarHBondContact NH1-OE1 3.32Å; C158-E160 VanDerWaalsContact C-N 3.28Å; C158-E160 WeakPolarHBondContact CB-O 3.29Å; C158-E160 PolarHBondContact O-N 2.91Å; C158-E160 PolarHBondContact SG-O 2.66Å; E160-K162 HydrophobicContact CB-CG 4Å; E160-K162 PolarHBondContact O-N 2.84Å; E160-K162 WeakPolarHBondContact OE2-CD 3.26Å; E160-K162 WeakPolarHBondContact OE2-CE 3.46Å; E160-K162 IonicContact OE2-NZ 2.95Å; E160-K162 PolarHBondContact OE2-NZ 2.68Å; E160-G163 PolarHBondContact O-N 3.44Å; E160-E332 WeakPolarHBondContact CB-OE1 3.49Å
161A97.7Very high92.1Very high0 Ų033.2 Ų33.20%018%0.182CC..G310 helixtrans-59.2-34-174.400000112.3F146 G163 L164 T165 V177 E332 W532F146-A161 HydrophobicContact CD1-CB 3.73Å; F146-A161 HydrophobicContact CD2-CB 4.33Å; F146-A161 HydrophobicContact CE1-CB 3.82Å; F146-A161 HydrophobicContact CE2-CB 4.42Å; F146-A161 HydrophobicContact CG-CB 3.99Å; F146-A161 HydrophobicContact CZ-CB 4.18Å; A161-G163 PolarHBondContact O-N 3Å; A161-L164 WeakPolarHBondContact O-CA 3.11Å; A161-L164 WeakPolarHBondContact O-CB 2.77Å; A161-L164 PolarHBondContact O-N 3.47Å; A161-T165 PolarHBondContact O-N 3.49Å; A161-V177 HydrophobicContact CB-CG1 3.91Å; A161-E332 VanDerWaalsContact N-CD 3.32Å; A161-E332 PolarHBondContact N-OE1 3.15Å; A161-E332 PolarHBondContact N-OE2 3.48Å; A161-W532 HydrophobicContact CB-CD2 4.23Å; A161-W532 HydrophobicContact CB-CE3 4.03Å; A161-W532 HydrophobicContact CB-CH2 3.36Å; A161-W532 HydrophobicContact CB-CZ2 3.56Å; A161-W532 HydrophobicContact CB-CZ3 3.61Å
162K96.3Very high91Very high2 Ų226.2 Ų26.21%0.00915%0.147CC..G310 helixtrans-55.1-26.317769.6-179.966.359.40113.7K23 I24 E160 L164 T165 F329 S330 E332 Y526K23-K162 WeakPolarHBondContact CD-O 3.36Å; K23-K162 PolarHBondContact NZ-O 3.14Å; I24-K162 HydrophobicContact CG2-CG 4.32Å; E160-K162 HydrophobicContact CB-CG 4Å; E160-K162 PolarHBondContact O-N 2.84Å; E160-K162 WeakPolarHBondContact OE2-CD 3.26Å; E160-K162 WeakPolarHBondContact OE2-CE 3.46Å; E160-K162 IonicContact OE2-NZ 2.95Å; E160-K162 PolarHBondContact OE2-NZ 2.68Å; K162-L164 PolarHBondContact O-N 3.31Å; K162-T165 PolarHBondContact O-OG1 3.44Å; K162-F329 HydrophobicContact CD-CE1 4.03Å; K162-F329 HydrophobicContact CD-CZ 3.83Å; K162-F329 WeakPolarHBondContact CE-O 3.41Å; K162-F329 PolarHBondContact NZ-O 2.91Å; K162-S330 PolarHBondContact NZ-O 3.04Å; K162-E332 VanDerWaalsContact CB-OE1 3.23Å; K162-E332 WeakPolarHBondContact CB-OE1 3.37Å; K162-E332 WeakPolarHBondContact CE-OE1 3.32Å; K162-E332 VanDerWaalsContact CG-OE1 3.27Å; K162-E332 WeakPolarHBondContact CG-OE1 3.48Å; K162-E332 PolarHBondContact N-OE1 3.34Å; K162-E332 VanDerWaalsContact NZ-CD 3.27Å; K162-E332 IonicContact NZ-OE1 3.32Å; K162-E332 PolarHBondContact NZ-OE1 2.98Å; K162-Y526 HydrophobicContact CB-CE1 3.89Å; K162-Y526 WeakPolarHBondContact CE-OH 3.07Å
163G96.3Very high89.7Confident0 Ų031.6 Ų31.60%018%0.175CC..G310 helixtrans-77.5-4.6174.900000114.4W5 S20 E160 A161W5-G163 PolarHBondContact NE1-O 3.39Å; W5-G163 VanDerWaalsContact NE1-O 3.1Å; S20-G163 PolarHBondContact OG-O 2.84Å; E160-G163 PolarHBondContact O-N 3.44Å; A161-G163 PolarHBondContact O-N 3Å
164L94.8Very high88.4Confident0 Ų035.2 Ų35.20%020%0.199CC..THydrogen-bonded Turntrans-116.8-21.4-179.7-57.8176.8000113.6F146 V148 C158 A161 K162 D166 L167 V177F146-L164 HydrophobicContact CB-CD1 3.88Å; V148-L164 HydrophobicContact CG2-CB 4.19Å; V148-L164 HydrophobicContact CG2-CD1 4.27Å; C158-L164 HydrophobicContact CB-CD1 3.89Å; C158-L164 HydrophobicContact CB-CD2 3.65Å; C158-L164 HydrophobicContact CB-CG 3.53Å; A161-L164 WeakPolarHBondContact O-CA 3.11Å; A161-L164 WeakPolarHBondContact O-CB 2.77Å; A161-L164 PolarHBondContact O-N 3.47Å; K162-L164 PolarHBondContact O-N 3.31Å; L164-D166 VanDerWaalsContact C-N 3.25Å; L164-D166 PolarHBondContact O-N 3.01Å; L164-L167 HydrophobicContact CB-CD1 4.22Å; L164-L167 HydrophobicContact CD2-CD1 3.56Å; L164-L167 WeakPolarHBondContact O-CB 3.49Å; L164-L167 WeakPolarHBondContact O-CG 3.37Å; L164-L167 PolarHBondContact O-N 2.97Å; L164-V177 HydrophobicContact CB-CG1 4.33Å; L164-V177 HydrophobicContact CB-CG2 3.87Å; L164-V177 HydrophobicContact CD1-CG1 4Å
165T90.6Very high87.4Confident32 Ų3235.4 Ų35.420%0.19620%0.2CC..THydrogen-bonded Turntrans-62.1-26.5-171.757.20000115.1A161 K162 Y526 W532A161-T165 PolarHBondContact O-N 3.49Å; K162-T165 PolarHBondContact O-OG1 3.44Å; T165-Y526 HydrophobicContact CG2-CD1 4.1Å; T165-Y526 HydrophobicContact CG2-CE1 4.44Å; T165-W532 HydrophobicContact CG2-CH2 3.77Å; T165-W532 HydrophobicContact CG2-CZ2 4.21Å
166D87.2Confident86.9Confident98 Ų9842.2 Ų42.252%0.52423%0.229SC..THydrogen-bonded Turntrans-105.87.7-175.2-62.223.2000111.9K23 L164 K168K23-D166 WeakPolarHBondContact CE-OD2 3.46Å; K23-D166 IonicContact NZ-OD1 2.89Å; K23-D166 PolarHBondContact NZ-OD1 3.01Å; K23-D166 IonicContact NZ-OD2 3.8Å; K23-D166 PolarHBondContact NZ-OD2 2.98Å; L164-D166 VanDerWaalsContact C-N 3.25Å; L164-D166 PolarHBondContact O-N 3.01Å; D166-K168 PolarHBondContact O-N 3.44Å
167L88.3Confident86.8Confident3 Ų342.3 Ų42.32%0.01623%0.23CC..  trans-65.7124175.9-67.5178.6000109.3W5 L7 Q17 F154 L164W5-L167 HydrophobicContact CZ2-CD2 4.03Å; L7-L167 HydrophobicContact CD1-CD2 4.39Å; L7-L167 HydrophobicContact CD2-CD1 3.74Å; L7-L167 HydrophobicContact CD2-CD2 4.27Å; Q17-L167 HydrophobicContact CB-CD2 4.41Å; Q17-L167 HydrophobicContact CG-CD2 4.36Å; F154-L167 HydrophobicContact CZ-CD1 4.28Å; L164-L167 HydrophobicContact CB-CD1 4.22Å; L164-L167 HydrophobicContact CD2-CD1 3.56Å; L164-L167 WeakPolarHBondContact O-CB 3.49Å; L164-L167 WeakPolarHBondContact O-CG 3.37Å; L164-L167 PolarHBondContact O-N 2.97Å
168K82.1Confident86.7Confident146 Ų14645.3 Ų45.364%0.63524%0.244SC*.  trans-94.5134.9171.3-61.5-175.5-178.2-178.20108.8Q17 D166Q17-K168 PolarHBondContact NE2-O 3.22Å; D166-K168 PolarHBondContact O-N 3.44Å
169H83.8Confident86.6Confident7 Ų746.7 Ų46.73%0.03225%0.253CS..BIsolated β-bridgetrans-138.1143.1173.7-170.545.9000110.3D11 D152 F154 T171 S172 K195D11-H169 IonicContact OD2-CE1 3.64Å; D11-H169 PolarHBondContact OD2-CE1 3.03Å; D11-H169 IonicContact OD2-ND1 3.9Å; D11-H169 IonicContact OD2-NE2 3.96Å; D152-H169 VanDerWaalsContact CG-NE2 3.29Å; D152-H169 IonicContact OD1-CD2 2.79Å; D152-H169 IonicContact OD1-NE2 2.82Å; D152-H169 PolarHBondContact OD1-NE2 2.98Å; D152-H169 IonicContact OD2-CD2 3.97Å; D152-H169 IonicContact OD2-CE1 3.7Å; D152-H169 PolarHBondContact OD2-CE1 3.12Å; D152-H169 IonicContact OD2-NE2 2.78Å; D152-H169 PolarHBondContact OD2-NE2 2.77Å; F154-H169 WeakPolarHBondContact CB-NE2 3.48Å; F154-H169 HydrophobicContact CD1-CB 4.02Å; F154-H169 AromaticContact CD1-CG 3.74Å; F154-H169 HydrophobicContact CE1-CB 4.18Å; F154-H169 AromaticContact CG-CG 3.88Å; F154-H169 AromaticContact CG-ND1 3.86Å; H169-T171 PolarHBondContact CD2-OG1 3.15Å; H169-T171 PolarHBondContact NE2-OG1 3.25Å; H169-T171 PolarHBondContact O-N 3.17Å; H169-T171 VanDerWaalsContact O-N 3.13Å; H169-S172 PolarHBondContact N-O 2.9Å; H169-S172 CarbonylContact O-C 3.49Å; H169-S172 PolarHBondContact O-N 3.11Å; H169-K195 PolarHBondContact CE1-NZ 2.64Å
170S79.3Confident86.6Confident78 Ų7846.8 Ų46.855%0.54525%0.254SS..THydrogen-bonded Turntrans-56.9-33.7-170.662.70000113.3D11D11-S170 PolarHBondContact OD2-OG 2.98Å
171T72.2Confident86.6Confident88 Ų8850 Ų5054%0.5427%0.271SS..THydrogen-bonded Turntrans-96.5-9-179.260.40000113.7D152 H169D152-T171 HydrophobicContact CB-CG2 4.4Å; D152-T171 PolarHBondContact OD1-OG1 3.33Å; H169-T171 PolarHBondContact CD2-OG1 3.15Å; H169-T171 PolarHBondContact NE2-OG1 3.25Å; H169-T171 PolarHBondContact O-N 3.17Å; H169-T171 VanDerWaalsContact O-N 3.13Å
172S68.9Low86.6Confident33 Ų3350.5 Ų50.523%0.23127%0.273CS..BIsolated β-bridgetrans-149.8116.1-178.3-171.80000112.4H169 C174H169-S172 PolarHBondContact N-O 2.9Å; H169-S172 CarbonylContact O-C 3.49Å; H169-S172 PolarHBondContact O-N 3.11Å; S172-C174 VanDerWaalsContact C-N 3.32Å; S172-C174 PolarHBondContact OG-O 2.85Å
173L65.4Low86.6Confident170 Ų17050.4 Ų50.489%0.8927%0.273SS*.SBendtrans-75.5-20.9176.6-71.4165.3000113
174C68.1Low86.7Confident81 Ų8152 Ų5255%0.54728%0.281SS..SBendtrans-144.782.8177.6-170.30000108.5S172S172-C174 VanDerWaalsContact C-N 3.32Å; S172-C174 PolarHBondContact OG-O 2.85Å
175P74.9Confident86.9Confident4 Ų452.5 Ų52.53%0.02628%0.283CS..  trans-61.2140.3179.718.5-27000111.4V148 V177V148-P175 HydrophobicContact CB-CB 4.23Å; V148-P175 HydrophobicContact CG1-CB 3.28Å; V148-P175 HydrophobicContact CG1-CG 4Å; V148-P175 HydrophobicContact CG2-CB 3.93Å; V148-P175 HydrophobicContact CG2-CG 4.27Å; P175-V177 PolarHBondContact O-N 3.39Å; P175-V177 VanDerWaalsContact O-N 3.09Å
176K88.1Confident87.3Confident143 Ų14351.1 Ų51.162%0.62227%0.274SS*.  trans-67109.9176.6-174.2-172.2176.3-155.10109.5E178K176-E178 IonicContact NZ-OE2 3.41Å
177V95Very high87.8Confident2 Ų246.8 Ų46.81%0.01225%0.251CS..EExtended strand (participates in β ladder)trans-85.8132.4172.6-1760000108.5F146 K147 V148 A161 L164 P175 W532F146-V177 HydrophobicContact CB-CG1 4.14Å; F146-V177 HydrophobicContact CD1-CG1 4.03Å; F146-V177 HydrophobicContact CG-CG1 4.48Å; K147-V177 WeakPolarHBondContact O-CA 3.45Å; V148-V177 HydrophobicContact CG2-CB 4.2Å; V148-V177 HydrophobicContact CG2-CG2 3.6Å; A161-V177 HydrophobicContact CB-CG1 3.91Å; L164-V177 HydrophobicContact CB-CG1 4.33Å; L164-V177 HydrophobicContact CB-CG2 3.87Å; L164-V177 HydrophobicContact CD1-CG1 4Å; P175-V177 PolarHBondContact O-N 3.39Å; P175-V177 VanDerWaalsContact O-N 3.09Å; V177-W532 HydrophobicContact CB-CZ2 3.81Å; V177-W532 HydrophobicContact CG1-CZ2 3.94Å; V177-W532 HydrophobicContact CG2-CZ2 4.32Å; V177-W532 PolarHBondContact O-NE1 3.44Å
178E95.6Very high88.3Confident64 Ų6446.6 Ų46.630%0.29925%0.25SS..EExtended strand (participates in β ladder)trans-136145.9175.761.4-172.6-169.500112F146 K147 K176 F180F146-E178 CarbonylContact C-O 3.53Å; F146-E178 VanDerWaalsContact CA-O 3.3Å; F146-E178 WeakPolarHBondContact CA-O 3.32Å; K147-E178 WeakPolarHBondContact CE-OE1 3.43Å; K147-E178 HydrophobicContact CG-CG 3.96Å; K147-E178 PolarHBondContact N-O 3.18Å; K147-E178 IonicContact NZ-OE1 2.7Å; K147-E178 PolarHBondContact O-N 3.15Å; K176-E178 IonicContact NZ-OE2 3.41Å; E178-F180 PolarHBondContact O-N 3.25Å
179P97.7Very high89.1Confident29 Ų2942 Ų4219%0.18823%0.232CC..EExtended strand (participates in β ladder)trans-61133.8169.9-15.626.4000110.6F146 Y398F146-P179 HydrophobicContact CD1-CB 4.21Å; F146-P179 HydrophobicContact CD1-CG 4.16Å; F146-P179 HydrophobicContact CE1-CB 3.95Å; F146-P179 HydrophobicContact CE1-CG 3.66Å; F146-P179 HydrophobicContact CZ-CB 4.47Å; F146-P179 HydrophobicContact CZ-CG 4.41Å; P179-Y398 HydrophobicContact CB-CE2 4.07Å
180F98.4Very high89.8Confident2 Ų241.9 Ų41.91%0.00923%0.232CC..PPolyproline II helixtrans-78.4131.4169.9-173.9-86000109.7L135 R137 L145 K147 E178 H184 E186 L201L135-F180 HydrophobicContact CB-CD2 4.17Å; L135-F180 HydrophobicContact CB-CE2 3.55Å; L135-F180 HydrophobicContact CB-CZ 3.77Å; L135-F180 HydrophobicContact CD1-CD2 4.06Å; L135-F180 HydrophobicContact CD1-CE2 3.95Å; L135-F180 HydrophobicContact CG-CE2 4.37Å; R137-F180 HydrophobicContact CB-CD1 3.68Å; R137-F180 HydrophobicContact CB-CE1 3.95Å; R137-F180 WeakPolarHBondContact CD-O 3.47Å; R137-F180 PolarHBondContact NH1-O 3.44Å; L145-F180 HydrophobicContact CB-CB 3.95Å; L145-F180 HydrophobicContact CD2-CB 4.1Å; L145-F180 HydrophobicContact CD2-CD1 4.02Å; L145-F180 HydrophobicContact CD2-CG 3.96Å; L145-F180 HydrophobicContact CG-CB 4.02Å; L145-F180 HydrophobicContact CG-CG 4.42Å; L145-F180 WeakPolarHBondContact O-CB 3.38Å; L145-F180 PolarHBondContact O-N 3.35Å; K147-F180 HydrophobicContact CD-CD2 4.22Å; E178-F180 PolarHBondContact O-N 3.25Å; F180-H184 HydrophobicContact CE1-CB 4.26Å; F180-H184 WeakPolarHBondContact CE1-O 3.39Å; F180-H184 HydrophobicContact CZ-CB 4.5Å; F180-E186 HydrophobicContact CE2-CB 3.67Å; F180-E186 WeakPolarHBondContact CE2-OE2 3.06Å; F180-E186 HydrophobicContact CZ-CB 3.94Å; F180-L201 HydrophobicContact CE2-CD1 4.1Å; F180-L201 HydrophobicContact CZ-CD1 4.03Å
181L97.8Very high90.7Very high69 Ų6941.7 Ų41.736%0.36122%0.221SC..PPolyproline II helixtrans-65.8137-169-62.4179.6000112.9H184 L201L181-H184 HydrophobicContact CB-CB 4.35Å; L181-H184 WeakPolarHBondContact CB-ND1 3.24Å; L181-L201 HydrophobicContact CD1-CD2 4.21Å
182P98Very high91.9Very high9 Ų942.2 Ų42.26%0.05823%0.226CC..THydrogen-bonded Turntrans-58.6146.1169.5-26.736.7000113.5D138 T139 H184 Y398D138-P182 CarbonylContact O-C 3.57Å; D138-P182 WeakPolarHBondContact O-CA 3.48Å; T139-P182 WeakPolarHBondContact O-CB 3.41Å; P182-H184 PolarHBondContact O-CE1 2.77Å; P182-H184 PolarHBondContact O-N 2.93Å; P182-H184 PolarHBondContact O-ND1 3.49Å; P182-Y398 HydrophobicContact CG-CD1 3.48Å; P182-Y398 VanDerWaalsContact CG-CD1 3.48Å; P182-Y398 HydrophobicContact CG-CD2 4.12Å; P182-Y398 HydrophobicContact CG-CE1 4.05Å; P182-Y398 HydrophobicContact CG-CG 3.5Å
183G97Very high93.2Very high1 Ų144 Ų441%0.0124%0.239CC..THydrogen-bonded Turntrans6622.2176.800000114.2R137 D138 K203 F204R137-G183 PolarHBondContact O-N 3.24Å; R137-G183 VanDerWaalsContact O-N 3.14Å; D138-G183 PolarHBondContact O-N 3.34Å; G183-K203 WeakPolarHBondContact O-CA 3.47Å; G183-F204 WeakPolarHBondContact O-CD1 3.46Å; G183-F204 PolarHBondContact O-N 3.32Å
184H97.9Very high94.7Very high34 Ų3435.9 Ų35.916%0.15720%0.196CC..EExtended strand (participates in β ladder)trans-121.5155177.3-65.970.7000111.9G136 R137 F180 L181 P182 L201 V202 K203G136-H184 WeakPolarHBondContact CA-O 3.2Å; R137-H184 PolarHBondContact N-O 3.44Å; F180-H184 HydrophobicContact CE1-CB 4.26Å; F180-H184 WeakPolarHBondContact CE1-O 3.39Å; F180-H184 HydrophobicContact CZ-CB 4.5Å; L181-H184 HydrophobicContact CB-CB 4.35Å; L181-H184 WeakPolarHBondContact CB-ND1 3.24Å; P182-H184 PolarHBondContact O-CE1 2.77Å; P182-H184 PolarHBondContact O-N 2.93Å; P182-H184 PolarHBondContact O-ND1 3.49Å; H184-L201 HydrophobicContact CB-CD1 3.97Å; H184-V202 CarbonylContact C-O 3.51Å; H184-V202 WeakPolarHBondContact CA-O 3.47Å; H184-V202 WeakPolarHBondContact CB-O 3.47Å; H184-K203 PolarHBondContact CD2-N 3.36Å; H184-K203 WeakPolarHBondContact NE2-CB 3.47Å
185Y98.5Very high96.1Very high9 Ų933.2 Ų33.24%0.03518%0.175CC..EExtended strand (participates in β ladder)trans-122.7153157.669.1-96.3000110I110 E111 A114 L135 V187 V202 F204I110-Y185 HydrophobicContact CG1-CD2 3.89Å; I110-Y185 HydrophobicContact CG1-CE2 4.46Å; I110-Y185 HydrophobicContact CG1-CG 4.06Å; I110-Y185 HydrophobicContact CG2-CD2 3.79Å; I110-Y185 HydrophobicContact CG2-CE2 3.53Å; E111-Y185 HydrophobicContact CB-CE1 4.22Å; E111-Y185 HydrophobicContact CG-CE1 4.33Å; A114-Y185 HydrophobicContact CB-CD1 3.9Å; L135-Y185 CarbonylContact O-C 3.6Å; L135-Y185 WeakPolarHBondContact O-CA 3.45Å; L135-Y185 VanDerWaalsContact O-CB 3.31Å; L135-Y185 WeakPolarHBondContact O-CB 3.3Å; Y185-V187 HydrophobicContact CD2-CG2 3.99Å; Y185-V187 HydrophobicContact CE2-CG2 3.81Å; Y185-V202 HydrophobicContact CD1-CB 4.31Å; Y185-V202 HydrophobicContact CD2-CB 4.37Å; Y185-V202 HydrophobicContact CE1-CB 3.74Å; Y185-V202 HydrophobicContact CE1-CG1 3.77Å; Y185-V202 HydrophobicContact CE2-CB 3.81Å; Y185-V202 HydrophobicContact CE2-CG2 3.91Å; Y185-V202 VanDerWaalsContact CZ-CB 3.47Å; Y185-V202 PolarHBondContact N-O 3.1Å; Y185-V202 PolarHBondContact O-N 3.24Å; Y185-F204 HydrophobicContact CD1-CB 3.93Å; Y185-F204 HydrophobicContact CD1-CD1 4.08Å; Y185-F204 HydrophobicContact CD1-CG 4.39Å; Y185-F204 HydrophobicContact CE1-CB 4.01Å
186E98.7Very high97.2Very high4 Ų433.3 Ų33.32%0.01918%0.176CC..EExtended strand (participates in β ladder)trans-122.1137.2175.8-171.4174.8-171.700109.5F134 L135 K147 F180 L188 S198 E200 L201F134-E186 VanDerWaalsContact CA-O 3.27Å; F134-E186 WeakPolarHBondContact CA-O 3.4Å; L135-E186 HydrophobicContact CB-CB 4.3Å; L135-E186 PolarHBondContact N-O 3.4Å; L135-E186 VanDerWaalsContact N-O 3.07Å; L135-E186 PolarHBondContact O-N 3.43Å; K147-E186 IonicContact NZ-OE1 3.67Å; K147-E186 PolarHBondContact NZ-OE1 3.07Å; K147-E186 IonicContact NZ-OE2 2.88Å; K147-E186 PolarHBondContact NZ-OE2 2.81Å; F180-E186 HydrophobicContact CE2-CB 3.67Å; F180-E186 WeakPolarHBondContact CE2-OE2 3.06Å; F180-E186 HydrophobicContact CZ-CB 3.94Å; E186-L188 HydrophobicContact CB-CD1 4.28Å; E186-L188 HydrophobicContact CG-CD1 3.86Å; E186-L188 HydrophobicContact CG-CG 4.17Å; E186-S198 WeakPolarHBondContact OE1-CB 3.44Å; E186-S198 PolarHBondContact OE1-OG 3.07Å; E186-E200 CarbonylContact C-O 3.04Å; E186-E200 WeakPolarHBondContact CA-O 3.44Å; E186-E200 WeakPolarHBondContact CG-O 3.36Å; E186-L201 HydrophobicContact CB-CD1 3.85Å; E186-L201 HydrophobicContact CG-CD1 4.31Å
187V98.8Very high97.7Very high6 Ų628.2 Ų28.24%0.03616%0.16CC..EExtended strand (participates in β ladder)trans-106.6125.5175.5-175.70000108.4I110 K132 F134 Y185 V199 E200I110-V187 HydrophobicContact CG2-CG2 4.13Å; K132-V187 HydrophobicContact CD-CG1 4.04Å; F134-V187 HydrophobicContact CD1-CB 4.36Å; F134-V187 HydrophobicContact CD1-CG1 4.25Å; F134-V187 HydrophobicContact CD1-CG2 3.95Å; F134-V187 HydrophobicContact CE1-CB 4.31Å; F134-V187 HydrophobicContact CE1-CG1 3.78Å; F134-V187 HydrophobicContact CE1-CG2 3.93Å; Y185-V187 HydrophobicContact CD2-CG2 3.99Å; Y185-V187 HydrophobicContact CE2-CG2 3.81Å; V187-V199 HydrophobicContact CB-CB 4.45Å; V187-V199 HydrophobicContact CG1-CB 4.44Å; V187-V199 WeakPolarHBondContact O-CB 3.25Å; V187-V199 PolarHBondContact O-N 3.38Å; V187-E200 HydrophobicContact CB-CG 3.83Å; V187-E200 HydrophobicContact CG2-CG 3.76Å; V187-E200 PolarHBondContact N-O 3.27Å; V187-E200 PolarHBondContact O-N 2.86Å
188L98.8Very high97.7Very high0 Ų030.9 Ų30.90%018%0.179CC..EExtended strand (participates in β ladder)trans-124.6138.3175.2-51.696.6000110.7K132 V133 L135 L149 L155 E186 V196 A197K132-L188 CarbonylContact C-O 3.52Å; K132-L188 VanDerWaalsContact CA-O 3.3Å; K132-L188 WeakPolarHBondContact CA-O 3.26Å; V133-L188 HydrophobicContact CB-CB 4.35Å; V133-L188 PolarHBondContact N-O 2.74Å; V133-L188 PolarHBondContact O-N 3Å; L135-L188 HydrophobicContact CD1-CD1 4.34Å; L135-L188 HydrophobicContact CG-CD1 4.07Å; L149-L188 HydrophobicContact CD2-CD2 4.44Å; L155-L188 HydrophobicContact CD1-CD2 4.49Å; L155-L188 HydrophobicContact CD2-CD2 4.23Å; E186-L188 HydrophobicContact CB-CD1 4.28Å; E186-L188 HydrophobicContact CG-CD1 3.86Å; E186-L188 HydrophobicContact CG-CG 4.17Å; L188-V196 HydrophobicContact CB-CB 4.13Å; L188-V196 HydrophobicContact CD2-CB 4.28Å; L188-V196 HydrophobicContact CD2-CG2 3.8Å; L188-A197 CarbonylContact C-O 3.55Å; L188-A197 VanDerWaalsContact CA-O 3.26Å; L188-A197 WeakPolarHBondContact CA-O 3.32Å
189D98.6Very high97.8Very high49 Ų4931.5 Ų31.526%0.26219%0.187SC..EExtended strand (participates in β ladder)trans-76.1126.2170.6-82.2-12.6000110.6K132 K191 V196 A197 V199K132-D189 WeakPolarHBondContact CE-OD1 3.43Å; K132-D189 IonicContact NZ-OD1 3.61Å; K132-D189 PolarHBondContact NZ-OD1 2.84Å; D189-K191 HydrophobicContact CB-CD 4.41Å; D189-K191 IonicContact OD2-NZ 3.55Å; D189-K191 PolarHBondContact OD2-NZ 3.22Å; D189-K191 VanDerWaalsContact OD2-NZ 3.11Å; D189-V196 CarbonylContact O-C 3.56Å; D189-V196 WeakPolarHBondContact O-CA 2.94Å; D189-A197 PolarHBondContact N-O 3.12Å; D189-A197 PolarHBondContact O-N 2.76Å; D189-V199 HydrophobicContact CB-CG2 4.38Å
190L98.6Very high97.8Very high4 Ų434.5 Ų34.52%0.02120%0.198CC..EExtended strand (participates in β ladder)trans-82.1116.6167.8-176.667.1000110.1F8 F40 L126 R131 G194 V196F8-L190 HydrophobicContact CD1-CD1 4.44Å; F40-L190 HydrophobicContact CD1-CD1 4.48Å; F40-L190 HydrophobicContact CD1-CD2 4.1Å; F40-L190 HydrophobicContact CD1-CG 4.35Å; F40-L190 HydrophobicContact CD2-CD2 3.97Å; F40-L190 HydrophobicContact CE1-CD2 3.84Å; F40-L190 HydrophobicContact CE1-CG 3.99Å; F40-L190 HydrophobicContact CE2-CD2 3.69Å; F40-L190 HydrophobicContact CG-CD2 4.15Å; F40-L190 HydrophobicContact CZ-CD2 3.62Å; F40-L190 HydrophobicContact CZ-CG 4.15Å; L126-L190 HydrophobicContact CD1-CD2 3.74Å; R131-L190 HydrophobicContact CB-CB 4.13Å; R131-L190 WeakPolarHBondContact CB-O 3.49Å; R131-L190 PolarHBondContact O-N 3.06Å; L190-G194 WeakPolarHBondContact CD1-O 3.29Å; L190-V196 HydrophobicContact CD1-CG1 4.13Å
191K98.1Very high97.8Very high75 Ų7538.3 Ų38.333%0.32622%0.218SC..PPolyproline II helixtrans-81.7157.6177.3-53.8-53.9-179.9-172.40110.4F40 D189 S193 G194 K195F40-K191 WeakPolarHBondContact CE1-O 3.47Å; D189-K191 HydrophobicContact CB-CD 4.41Å; D189-K191 IonicContact OD2-NZ 3.55Å; D189-K191 PolarHBondContact OD2-NZ 3.22Å; D189-K191 VanDerWaalsContact OD2-NZ 3.11Å; K191-S193 PolarHBondContact O-N 3.23Å; K191-G194 PolarHBondContact O-N 2.87Å; K191-K195 WeakPolarHBondContact CB-O 3.35Å; K191-K195 PolarHBondContact N-O 3.35Å
192P96.8Very high97.8Very high99 Ų9936.6 Ų36.664%0.64321%0.211SC*.THydrogen-bonded Turntrans-55.4-24.4176.4-2735.8000114.5G194P192-G194 VanDerWaalsContact C-N 3.26Å; P192-G194 PolarHBondContact O-N 3.11Å
193S95.8Very high97.7Very high70 Ų7041.1 Ų41.149%0.4923%0.23SC..THydrogen-bonded Turntrans-75.2-6.9174.956.20000114.3N42 K191 K195N42-S193 PolarHBondContact ND2-O 3.33Å; K191-S193 PolarHBondContact O-N 3.23Å; S193-K195 PolarHBondContact O-N 3.01Å; S193-K195 WeakPolarHBondContact OG-CG 3.26Å
194G97.1Very high97.5Very high0 Ų042.5 Ų42.50%024%0.235CC..SBendtrans84.5-12.5-171.400000114.5F8 G9 C43 L190 K191 P192F8-G194 CarbonylContact C-O 3.34Å; G9-G194 VanDerWaalsContact CA-C 3.48Å; G9-G194 WeakPolarHBondContact CA-O 3.49Å; G9-G194 PolarHBondContact N-O 3.46Å; C43-G194 PolarHBondContact SG-O 3.11Å; C43-G194 VanDerWaalsContact SG-O 3.34Å; L190-G194 WeakPolarHBondContact CD1-O 3.29Å; K191-G194 PolarHBondContact O-N 2.87Å; P192-G194 VanDerWaalsContact C-N 3.26Å; P192-G194 PolarHBondContact O-N 3.11Å
195K97.4Very high96.8Very high25 Ų2542 Ų4211%0.10923%0.233CC..  trans-66.8162.2170.5-58.5-76.5178.9175.60110.6G9 D11 D152 G153 H169 K191 S193G9-K195 WeakPolarHBondContact O-CD 3.24Å; G9-K195 WeakPolarHBondContact O-CE 3.49Å; G9-K195 PolarHBondContact O-NZ 2.92Å; D11-K195 WeakPolarHBondContact OD1-CE 3.49Å; D11-K195 IonicContact OD1-NZ 3.6Å; D11-K195 PolarHBondContact OD1-NZ 2.85Å; D11-K195 IonicContact OD2-NZ 2.82Å; D11-K195 PolarHBondContact OD2-NZ 3.43Å; D152-K195 WeakPolarHBondContact O-CD 3.32Å; D152-K195 IonicContact OD2-NZ 3.43Å; D152-K195 PolarHBondContact OD2-NZ 2.66Å; G153-K195 CarbonylContact O-C 3.56Å; G153-K195 WeakPolarHBondContact O-CA 3.25Å; G153-K195 WeakPolarHBondContact O-CB 3.3Å; H169-K195 PolarHBondContact CE1-NZ 2.64Å; K191-K195 WeakPolarHBondContact CB-O 3.35Å; K191-K195 PolarHBondContact N-O 3.35Å; S193-K195 PolarHBondContact O-N 3.01Å; S193-K195 WeakPolarHBondContact OG-CG 3.26Å
196V98.4Very high96Very high6 Ų643.7 Ų43.74%0.03625%0.246CC..EExtended strand (participates in β ladder)trans-123.4158.8179-58.10000112.8F8 V133 L149 G153 L155 L188 D189 L190F8-V196 HydrophobicContact CB-CG1 3.83Å; F8-V196 HydrophobicContact CG-CG1 4.3Å; V133-V196 HydrophobicContact CG2-CG1 4.06Å; L149-V196 HydrophobicContact CD1-CG2 3.84Å; G153-V196 WeakPolarHBondContact CA-O 3.47Å; G153-V196 PolarHBondContact O-N 2.95Å; L155-V196 HydrophobicContact CB-CG2 3.47Å; L155-V196 VanDerWaalsContact CB-CG2 3.47Å; L155-V196 HydrophobicContact CD2-CG2 4.06Å; L155-V196 HydrophobicContact CG-CG2 4.29Å; L188-V196 HydrophobicContact CB-CB 4.13Å; L188-V196 HydrophobicContact CD2-CB 4.28Å; L188-V196 HydrophobicContact CD2-CG2 3.8Å; D189-V196 CarbonylContact O-C 3.56Å; D189-V196 WeakPolarHBondContact O-CA 2.94Å; L190-V196 HydrophobicContact CD1-CG1 4.13Å
197A98.1Very high95.1Very high36 Ų3644.4 Ų44.430%0.29825%0.249SC..EExtended strand (participates in β ladder)trans-131.2126.5167.700000109.1L188 D189 V199L188-A197 CarbonylContact C-O 3.55Å; L188-A197 VanDerWaalsContact CA-O 3.26Å; L188-A197 WeakPolarHBondContact CA-O 3.32Å; D189-A197 PolarHBondContact N-O 3.12Å; D189-A197 PolarHBondContact O-N 2.76Å; A197-V199 PolarHBondContact O-N 2.72Å
198S96.7Very high94Very high57 Ų5749.4 Ų49.440%0.39927%0.27SS..EExtended strand (participates in β ladder)trans-64.4134.4175.4-170.10000109.9E186E186-S198 WeakPolarHBondContact OE1-CB 3.44Å; E186-S198 PolarHBondContact OE1-OG 3.07Å
199V97.3Very high93.4Very high77 Ų7754 Ų5447%0.46730%0.295SS..EExtended strand (participates in β ladder)trans-105.5-52.8180179.20000109.2V187 D189 A197V187-V199 HydrophobicContact CB-CB 4.45Å; V187-V199 HydrophobicContact CG1-CB 4.44Å; V187-V199 WeakPolarHBondContact O-CB 3.25Å; V187-V199 PolarHBondContact O-N 3.38Å; D189-V199 HydrophobicContact CB-CG2 4.38Å; A197-V199 PolarHBondContact O-N 2.72Å
200E97.1Very high92.7Very high92 Ų9257.7 Ų57.743%0.4331%0.31SS..EExtended strand (participates in β ladder)trans-154.5149-178.359.9-175161.900111.4E186 V187 V202E186-E200 CarbonylContact C-O 3.04Å; E186-E200 WeakPolarHBondContact CA-O 3.44Å; E186-E200 WeakPolarHBondContact CG-O 3.36Å; V187-E200 HydrophobicContact CB-CG 3.83Å; V187-E200 HydrophobicContact CG2-CG 3.76Å; V187-E200 PolarHBondContact N-O 3.27Å; V187-E200 PolarHBondContact O-N 2.86Å; E200-V202 HydrophobicContact CB-CG2 4.17Å; E200-V202 HydrophobicContact CG-CG2 3.95Å
201L97.8Very high92.3Very high82 Ų8257.8 Ų57.843%0.42931%0.311SS..EExtended strand (participates in β ladder)trans-120.1114.7170.4177.468.8000107.2F180 L181 H184 E186F180-L201 HydrophobicContact CE2-CD1 4.1Å; F180-L201 HydrophobicContact CZ-CD1 4.03Å; L181-L201 HydrophobicContact CD1-CD2 4.21Å; H184-L201 HydrophobicContact CB-CD1 3.97Å; E186-L201 HydrophobicContact CB-CD1 3.85Å; E186-L201 HydrophobicContact CG-CD1 4.31Å
202V98.1Very high91.8Very high33 Ų3360 Ų6020%0.233%0.326CS..EExtended strand (participates in β ladder)trans-119.7129.1-168.6-178.10000110H184 Y185 E200H184-V202 CarbonylContact C-O 3.51Å; H184-V202 WeakPolarHBondContact CA-O 3.47Å; H184-V202 WeakPolarHBondContact CB-O 3.47Å; Y185-V202 HydrophobicContact CD1-CB 4.31Å; Y185-V202 HydrophobicContact CD2-CB 4.37Å; Y185-V202 HydrophobicContact CE1-CB 3.74Å; Y185-V202 HydrophobicContact CE1-CG1 3.77Å; Y185-V202 HydrophobicContact CE2-CB 3.81Å; Y185-V202 HydrophobicContact CE2-CG2 3.91Å; Y185-V202 VanDerWaalsContact CZ-CB 3.47Å; Y185-V202 PolarHBondContact N-O 3.1Å; Y185-V202 PolarHBondContact O-N 3.24Å; E200-V202 HydrophobicContact CB-CG2 4.17Å; E200-V202 HydrophobicContact CG-CG2 3.95Å
203K96.1Very high91.5Very high105 Ų10555.5 Ų55.546%0.45730%0.296SS..EExtended strand (participates in β ladder)trans-80.1117.4169.5-169179.2-179.4-1700109.1G183 H184 H205G183-K203 WeakPolarHBondContact O-CA 3.47Å; H184-K203 PolarHBondContact CD2-N 3.36Å; H184-K203 WeakPolarHBondContact NE2-CB 3.47Å; K203-H205 WeakPolarHBondContact CE-O 3.43Å
204F92.9Very high91.1Very high30 Ų3052.6 Ų52.613%0.13228%0.277CS..  trans-99.3-10.4-173.469.3-98.1000114A114 C115 F121 R137 G183 Y185A114-F204 HydrophobicContact CB-CB 4.1Å; A114-F204 HydrophobicContact CB-CD1 3.82Å; A114-F204 HydrophobicContact CB-CD2 3.95Å; A114-F204 HydrophobicContact CB-CE1 4.2Å; A114-F204 HydrophobicContact CB-CE2 4.34Å; A114-F204 HydrophobicContact CB-CG 3.69Å; A114-F204 HydrophobicContact CB-CZ 4.46Å; A114-F204 WeakPolarHBondContact O-CE2 3.3Å; C115-F204 PolarHBondContact SG-O 3.42Å; C115-F204 VanDerWaalsContact SG-O 3.4Å; F121-F204 HydrophobicContact CE2-CZ 4.41Å; F121-F204 AromaticContact CZ-CZ 3.93Å; F121-F204 HydrophobicContact CZ-CZ 3.93Å; R137-F204 VanDerWaalsContact O-CE1 3.3Å; R137-F204 WeakPolarHBondContact O-CE1 3.18Å; R137-F204 WeakPolarHBondContact O-CZ 3.41Å; G183-F204 WeakPolarHBondContact O-CD1 3.46Å; G183-F204 PolarHBondContact O-N 3.32Å; Y185-F204 HydrophobicContact CD1-CB 3.93Å; Y185-F204 HydrophobicContact CD1-CD1 4.08Å; Y185-F204 HydrophobicContact CD1-CG 4.39Å; Y185-F204 HydrophobicContact CE1-CB 4.01Å
205H82.9Confident90.6Very high24 Ų2456.6 Ų56.611%0.11131%0.309CS..  trans-138.6144.4-177.4-176.871.9000113.1T139 K203T139-H205 WeakPolarHBondContact CG2-CD2 3.28Å; T139-H205 PolarHBondContact OG1-CD2 3.42Å; K203-H205 WeakPolarHBondContact CE-O 3.43Å
206S82.5Confident89.9Confident44 Ų4458.6 Ų58.631%0.30832%0.317SS..  trans-118.5126.1174.9164.40000108.6K208 D209S206-K208 PolarHBondContact O-N 3.07Å; S206-D209 WeakPolarHBondContact CB-OD2 3.07Å; S206-D209 PolarHBondContact O-N 2.87Å; S206-D209 VanDerWaalsContact O-N 3.12Å; S206-D209 PolarHBondContact OG-OD2 3.41Å
207Y78.6Confident89.2Confident19 Ų1959.8 Ų59.88%0.07532%0.323CS..THydrogen-bonded Turntrans-62-17.9-173.8-48.3-75.6000114.6T139 Y140 K395 L430T139-Y207 HydrophobicContact CG2-CD1 3.63Å; T139-Y207 HydrophobicContact CG2-CE1 3.52Å; Y140-Y207 HydrophobicContact CD1-CD1 4.02Å; Y140-Y207 AromaticContact CD1-CE1 3.76Å; Y140-Y207 HydrophobicContact CD1-CE1 3.76Å; Y140-Y207 AromaticContact CE1-CD1 3.3Å; Y140-Y207 HydrophobicContact CE1-CD1 3.3Å; Y140-Y207 AromaticContact CE1-CE1 3.55Å; Y140-Y207 HydrophobicContact CE1-CE1 3.55Å; Y140-Y207 HydrophobicContact CE1-CG 4.39Å; Y140-Y207 AromaticContact CZ-CD1 3.79Å; Y207-K395 HydrophobicContact CD2-CG 4.33Å; Y207-K395 HydrophobicContact CE2-CD 4.29Å; Y207-K395 HydrophobicContact CE2-CG 3.47Å; Y207-K395 VanDerWaalsContact CE2-CG 3.47Å; Y207-L430 VanDerWaalsContact O-CD1 3.29Å; Y207-L430 WeakPolarHBondContact O-CD1 3.14Å
208K77.3Confident88.3Confident111 Ų11162.2 Ų62.248%0.48333%0.334SS..THydrogen-bonded Turntrans-90.6-22.1-178.7-65.8-173.5179.1-173.70112.9S206 E391S206-K208 PolarHBondContact O-N 3.07Å; K208-E391 WeakPolarHBondContact CE-OE1 3.48Å; K208-E391 WeakPolarHBondContact CE-OE2 3.31Å; K208-E391 IonicContact NZ-OE1 3Å; K208-E391 PolarHBondContact NZ-OE1 2.92Å; K208-E391 IonicContact NZ-OE2 3.62Å; K208-E391 PolarHBondContact NZ-OE2 2.75Å
209D84.5Confident87.7Confident97 Ų9760.8 Ų60.852%0.51932%0.323SS..SBendtrans-90.5143.8-173.2-58.5-46000109.1S206 S427S206-D209 WeakPolarHBondContact CB-OD2 3.07Å; S206-D209 PolarHBondContact O-N 2.87Å; S206-D209 VanDerWaalsContact O-N 3.12Å; S206-D209 PolarHBondContact OG-OD2 3.41Å; D209-S427 WeakPolarHBondContact O-CB 3.31Å; D209-S427 PolarHBondContact O-OG 2.94Å
210E85.6Confident86.7Confident125 Ų12565.3 Ų65.358%0.58434%0.339SS*.PPolyproline II helixtrans-62.9127.3170.1-168.1174.2-147.600108.1A214 R424E210-A214 HydrophobicContact CG-CB 3.58Å; E210-R424 IonicContact OE1-NE 3.79Å; E210-R424 IonicContact OE1-NH2 2.92Å
211P88.2Confident86Confident6 Ų668.9 Ų68.94%0.03936%0.361CS..PPolyproline II helixtrans-65.3144.9-17628.5-37.5000110.7H213 A214 H423 R424P211-H213 VanDerWaalsContact CB-NE2 3.34Å; P211-H213 WeakPolarHBondContact CB-NE2 3.41Å; P211-H213 VanDerWaalsContact CG-CE1 3.49Å; P211-H213 WeakPolarHBondContact CG-CE1 3.29Å; P211-H213 PolarHBondContact O-N 3.12Å; P211-A214 HydrophobicContact CG-CB 4.24Å; P211-A214 WeakPolarHBondContact O-CB 3.35Å; P211-A214 PolarHBondContact O-N 3.38Å; P211-H423 HydrophobicContact CB-CB 4.33Å; P211-H423 HydrophobicContact CG-CB 3.85Å; P211-R424 HydrophobicContact CG-CG 4.03Å
212L88.9Confident85.4Confident121 Ų12167 Ų6763%0.63435%0.351SS*.G310 helixtrans-57.1-29.2-178.4-66.9-175000113.3C115 A214C115-L212 HydrophobicContact CB-CB 4.48Å; C115-L212 HydrophobicContact CB-CD1 3.87Å; C115-L212 HydrophobicContact CB-CG 4.48Å; L212-A214 PolarHBondContact O-N 2.73Å
213H90.1Very high84.9Confident5 Ų568.6 Ų68.62%0.02336%0.362CS..G310 helixtrans-70.2-15176.867.470.2000114.3M116 D118 P211 A215 Y216 H423M116-H213 VanDerWaalsContact O-CB 3.31Å; M116-H213 WeakPolarHBondContact O-CB 3.49Å; D118-H213 VanDerWaalsContact CB-CE1 3.47Å; D118-H213 WeakPolarHBondContact CB-CE1 3.49Å; D118-H213 WeakPolarHBondContact CB-ND1 3.33Å; D118-H213 IonicContact OD1-CE1 3.55Å; D118-H213 PolarHBondContact OD1-CE1 2.67Å; D118-H213 VanDerWaalsContact OD1-CE1 3.32Å; D118-H213 IonicContact OD1-NE2 2.69Å; P211-H213 VanDerWaalsContact CB-NE2 3.34Å; P211-H213 WeakPolarHBondContact CB-NE2 3.41Å; P211-H213 VanDerWaalsContact CG-CE1 3.49Å; P211-H213 WeakPolarHBondContact CG-CE1 3.29Å; P211-H213 PolarHBondContact O-N 3.12Å; H213-A215 PolarHBondContact O-N 3.03Å; H213-A215 VanDerWaalsContact O-N 3.15Å; H213-Y216 PolarHBondContact O-N 3.4Å; H213-H423 AromaticContact CE1-ND1 3.77Å; H213-H423 AromaticContact NE2-CG 3.68Å; H213-H423 AromaticContact NE2-ND1 3.11Å; H213-H423 PolarHBondContact NE2-ND1 3.06Å; H213-H423 VanDerWaalsContact NE2-ND1 3.11Å
214A88.1Confident84.4Confident10 Ų1068.9 Ų68.98%0.08338%0.378CS..G310 helixtrans-58.5-27.9176.700000112.4E210 P211 L212 Y216 D217 R424E210-A214 HydrophobicContact CG-CB 3.58Å; P211-A214 HydrophobicContact CG-CB 4.24Å; P211-A214 WeakPolarHBondContact O-CB 3.35Å; P211-A214 PolarHBondContact O-N 3.38Å; L212-A214 PolarHBondContact O-N 2.73Å; A214-Y216 PolarHBondContact O-N 2.61Å; A214-D217 PolarHBondContact O-N 2.93Å; A214-R424 HydrophobicContact CB-CG 3.94Å
215A85.6Confident84.2Confident83 Ų8369.4 Ų69.469%0.68639%0.392SS*.G310 helixtrans-60.8-14.2173.800000114H213H213-A215 PolarHBondContact O-N 3.03Å; H213-A215 VanDerWaalsContact O-N 3.15Å
216Y83.3Confident84.7Confident67 Ų6773.3 Ų73.326%0.26341%0.408SS..G310 helixtrans-121.310.6-177.9-50.2-80000113.1Q87 F88 M116 H213 A214Q87-Y216 HydrophobicContact CB-CD1 4.4Å; Q87-Y216 HydrophobicContact CG-CD1 3.6Å; Q87-Y216 HydrophobicContact CG-CE1 3.6Å; F88-Y216 HydrophobicContact CZ-CE1 4.22Å; M116-Y216 HydrophobicContact CE-CD2 3.38Å; M116-Y216 HydrophobicContact CE-CE2 3.12Å; M116-Y216 HydrophobicContact CE-CG 4.3Å; M116-Y216 HydrophobicContact SD-CD2 4.18Å; M116-Y216 HydrophobicContact SD-CE2 3.65Å; H213-Y216 PolarHBondContact O-N 3.4Å; A214-Y216 PolarHBondContact O-N 2.61Å
217D82.7Confident85.3Confident32 Ų3275.2 Ų75.217%0.17142%0.415CS..  trans-75.6160.9176.5-163.4-26.4000110.8A214 V219 N241 K245 R424A214-D217 PolarHBondContact O-N 2.93Å; D217-V219 PolarHBondContact OD1-N 3.32Å; D217-N241 PolarHBondContact OD1-ND2 3.01Å; D217-N241 PolarHBondContact OD2-ND2 2.8Å; D217-K245 IonicContact OD2-NZ 3.24Å; D217-K245 PolarHBondContact OD2-NZ 3.11Å; D217-R424 IonicContact OD1-NH1 3.57Å; D217-R424 WeakPolarHBondContact OD2-CD 3.45Å; D217-R424 IonicContact OD2-CZ 2.72Å; D217-R424 IonicContact OD2-NE 2.98Å; D217-R424 IonicContact OD2-NH1 3.59Å; D217-R424 PolarHBondContact OD2-NH1 3.25Å
218T79.9Confident86.1Confident86 Ų8677.8 Ų77.853%0.52843%0.43SS..SBendtrans-76.8-24.6175.853.80000114.3Q83 E220 N241Q83-T218 HydrophobicContact CG-CG2 4.31Å; T218-E220 PolarHBondContact O-N 3.06Å; T218-N241 PolarHBondContact OG1-OD1 3.22Å
219V84.4Confident87Confident27 Ų2777.4 Ų77.416%0.16443%0.43CS..SBendtrans-80.4113.3173171.20000108.6D217 L222 I237 N241 R424D217-V219 PolarHBondContact OD1-N 3.32Å; V219-L222 HydrophobicContact CG1-CD2 3.95Å; V219-I237 HydrophobicContact CG1-CG2 3.63Å; V219-I237 HydrophobicContact CG2-CG2 4.14Å; V219-N241 HydrophobicContact CG2-CB 3.53Å; V219-R424 PolarHBondContact O-NH1 3.06Å; V219-R424 PolarHBondContact O-NH2 3.47Å
220E77.2Confident87.6Confident173 Ų17373.9 Ų73.981%0.80841%0.412SS*.  trans-62.4-172.8175.5-62.6-172.3172.700112.5T218 L222T218-E220 PolarHBondContact O-N 3.06Å; E220-L222 PolarHBondContact O-N 3.32Å; E220-L222 VanDerWaalsContact O-N 3.17Å
221N80.7Confident88.2Confident166 Ų16668 Ų6889%0.88838%0.384SS*.PPolyproline II helixtrans-53.6120.7-178.7-66.6-32.3000111.6
222L86.8Confident88.6Confident42 Ų4267.9 Ų67.922%0.2238%0.383CS..PPolyproline II helixtrans-68.7144.3172.9-63.7172.4000109.8V219 E220 S224 N234 I237 L238 Y428V219-L222 HydrophobicContact CG1-CD2 3.95Å; E220-L222 PolarHBondContact O-N 3.32Å; E220-L222 VanDerWaalsContact O-N 3.17Å; L222-S224 PolarHBondContact O-N 2.7Å; L222-N234 HydrophobicContact CD2-CB 4.48Å; L222-I237 HydrophobicContact CD2-CG2 4.18Å; L222-L238 HydrophobicContact CD1-CD1 3.78Å; L222-L238 HydrophobicContact CD1-CD2 4.11Å; L222-L238 HydrophobicContact CD1-CG 4.1Å; L222-L238 HydrophobicContact CD2-CD2 4.32Å; L222-L238 HydrophobicContact CD2-CG 4.27Å; L222-Y428 HydrophobicContact CD1-CD2 4.1Å; L222-Y428 HydrophobicContact CD1-CE2 4.44Å
223P87.4Confident89Confident67 Ų6763.9 Ų63.944%0.43537%0.365SS..PPolyproline II helixtrans-53.8132.7168.18.6-16.9000110.9T230 N234P223-T230 HydrophobicContact CB-CG2 3.91Å; P223-T230 HydrophobicContact CG-CG2 4.28Å; P223-T230 WeakPolarHBondContact O-CG2 3.4Å; P223-N234 VanDerWaalsContact CD-OD1 3.22Å; P223-N234 WeakPolarHBondContact CD-OD1 3.16Å; P223-N234 WeakPolarHBondContact CG-OD1 3.26Å; P223-N234 PolarHBondContact O-ND2 2.88Å
224S85.4Confident89.3Confident112 Ų11263.7 Ų63.778%0.78336%0.364SS*.PPolyproline II helixtrans-82.7145.4-176.759.20000111.7L222L222-S224 PolarHBondContact O-N 2.7Å
225G89.1Confident89.8Confident41 Ų4163.2 Ų63.242%0.42336%0.361SS..SBendtrans115.1171177.400000112.5
226F92.3Very high90.4Very high105 Ų10562 Ų6246%0.46134%0.338SS..  trans-121.624.1-179.1-60.8-63.6000112.3V231 L432 P433 L436F226-V231 HydrophobicContact CB-CG2 4.41Å; F226-V231 HydrophobicContact CD1-CG2 4.38Å; F226-L432 HydrophobicContact CD1-CD2 3.69Å; F226-L432 HydrophobicContact CE1-CD2 3.84Å; F226-P433 HydrophobicContact CB-CG 4.33Å; F226-P433 HydrophobicContact CD2-CG 4.14Å; F226-P433 HydrophobicContact CG-CG 4.1Å; F226-L436 HydrophobicContact CB-CD1 4.44Å
227D95.4Very high91Very high85 Ų8562 Ų6246%0.45534%0.342SS..  trans-65.8149.2167.373.887.8000110E229 T230 V231D227-E229 VanDerWaalsContact C-N 3.31Å; D227-E229 PolarHBondContact O-N 3.42Å; D227-E229 PolarHBondContact OD1-N 2.89Å; D227-T230 VanDerWaalsContact CG-OG1 3.23Å; D227-T230 PolarHBondContact O-N 3.48Å; D227-T230 PolarHBondContact OD1-N 2.71Å; D227-T230 PolarHBondContact OD1-OG1 3.26Å; D227-T230 WeakPolarHBondContact OD2-CB 3.41Å; D227-T230 PolarHBondContact OD2-OG1 3.41Å; D227-V231 WeakPolarHBondContact O-CG2 3.11Å; D227-V231 PolarHBondContact O-N 3.02Å
228L95.3Very high91.7Very high73 Ų7360.5 Ų60.538%0.38233%0.334SS..Hα-helixtrans-60.6-38.5-166.9-177.161.3000113V231 K232 L447L228-V231 PolarHBondContact O-N 3.27Å; L228-K232 HydrophobicContact CD1-CD 4.34Å; L228-K232 HydrophobicContact CD1-CG 4.32Å; L228-K232 HydrophobicContact CG-CD 4.02Å; L228-K232 HydrophobicContact CG-CG 4.43Å; L228-K232 WeakPolarHBondContact O-CB 3.36Å; L228-K232 VanDerWaalsContact O-CG 3.24Å; L228-K232 WeakPolarHBondContact O-CG 3.17Å; L228-K232 PolarHBondContact O-N 3.08Å; L228-L447 HydrophobicContact CD1-CD1 3.83Å
229E95.9Very high92.6Very high102 Ų10256.4 Ų56.448%0.47731%0.309SS..Hα-helixtrans-74.4-38.2-178.1-72.5-55.7134.400112D227 K232 S233D227-E229 VanDerWaalsContact C-N 3.31Å; D227-E229 PolarHBondContact O-N 3.42Å; D227-E229 PolarHBondContact OD1-N 2.89Å; E229-K232 PolarHBondContact O-N 3.03Å; E229-K232 WeakPolarHBondContact OE1-CD 3.12Å; E229-K232 WeakPolarHBondContact OE1-CE 2.99Å; E229-K232 IonicContact OE1-NZ 3.69Å; E229-K232 PolarHBondContact OE1-NZ 2.9Å; E229-K232 IonicContact OE2-NZ 2.75Å; E229-S233 VanDerWaalsContact O-CB 3.29Å; E229-S233 WeakPolarHBondContact O-CB 3.41Å; E229-S233 PolarHBondContact O-N 3.39Å
230T96.7Very high93.3Very high24 Ų2456.9 Ų56.915%0.14731%0.309CS..Hα-helixtrans-59-47169.5-65.60000111.2P223 D227 S233 N234P223-T230 HydrophobicContact CB-CG2 3.91Å; P223-T230 HydrophobicContact CG-CG2 4.28Å; P223-T230 WeakPolarHBondContact O-CG2 3.4Å; D227-T230 VanDerWaalsContact CG-OG1 3.23Å; D227-T230 PolarHBondContact O-N 3.48Å; D227-T230 PolarHBondContact OD1-N 2.71Å; D227-T230 PolarHBondContact OD1-OG1 3.26Å; D227-T230 WeakPolarHBondContact OD2-CB 3.41Å; D227-T230 PolarHBondContact OD2-OG1 3.41Å; T230-S233 PolarHBondContact O-N 2.87Å; T230-N234 WeakPolarHBondContact O-CB 3.43Å; T230-N234 VanDerWaalsContact O-CG 3.28Å; T230-N234 PolarHBondContact O-N 2.66Å
231V97.9Very high94.3Very high0 Ų049 Ų490%027%0.273CS..Hα-helixtrans-62.3-48.8178.91740000111.5F226 D227 L228 S233 N234 I235 Y428 L432 L436 L447F226-V231 HydrophobicContact CB-CG2 4.41Å; F226-V231 HydrophobicContact CD1-CG2 4.38Å; D227-V231 WeakPolarHBondContact O-CG2 3.11Å; D227-V231 PolarHBondContact O-N 3.02Å; L228-V231 PolarHBondContact O-N 3.27Å; V231-S233 VanDerWaalsContact C-N 3.27Å; V231-S233 PolarHBondContact O-N 3.45Å; V231-N234 PolarHBondContact O-N 3.35Å; V231-I235 HydrophobicContact CG1-CD1 3.84Å; V231-I235 HydrophobicContact CG1-CG1 4.44Å; V231-I235 WeakPolarHBondContact O-CG1 3.31Å; V231-I235 PolarHBondContact O-N 2.89Å; V231-Y428 WeakPolarHBondContact CA-OH 3.46Å; V231-L432 HydrophobicContact CG1-CD1 3.84Å; V231-L432 HydrophobicContact CG1-CD2 3.86Å; V231-L432 HydrophobicContact CG2-CD2 3.91Å; V231-L436 HydrophobicContact CG2-CD1 4.45Å; V231-L447 HydrophobicContact CG1-CD1 4.03Å; V231-L447 HydrophobicContact CG1-CD2 3.95Å; V231-L447 HydrophobicContact CG1-CG 4.44Å
232K97.8Very high95.1Very high4 Ų441 Ų412%0.01723%0.23CC..Hα-helixtrans-56-43.2175.7-76.3172.253.9178.30111.3L228 E229 R236 Q450 E453 D454L228-K232 HydrophobicContact CD1-CD 4.34Å; L228-K232 HydrophobicContact CD1-CG 4.32Å; L228-K232 HydrophobicContact CG-CD 4.02Å; L228-K232 HydrophobicContact CG-CG 4.43Å; L228-K232 WeakPolarHBondContact O-CB 3.36Å; L228-K232 VanDerWaalsContact O-CG 3.24Å; L228-K232 WeakPolarHBondContact O-CG 3.17Å; L228-K232 PolarHBondContact O-N 3.08Å; E229-K232 PolarHBondContact O-N 3.03Å; E229-K232 WeakPolarHBondContact OE1-CD 3.12Å; E229-K232 WeakPolarHBondContact OE1-CE 2.99Å; E229-K232 IonicContact OE1-NZ 3.69Å; E229-K232 PolarHBondContact OE1-NZ 2.9Å; E229-K232 IonicContact OE2-NZ 2.75Å; K232-R236 WeakPolarHBondContact O-CG 2.98Å; K232-R236 PolarHBondContact O-N 3.44Å; K232-Q450 HydrophobicContact CD-CB 4.33Å; K232-Q450 VanDerWaalsContact CE-O 3.24Å; K232-Q450 WeakPolarHBondContact CE-O 3.43Å; K232-E453 IonicContact NZ-OE1 3.44Å; K232-E453 PolarHBondContact NZ-OE1 3.11Å; K232-D454 IonicContact NZ-OD2 3.52Å
233S96.6Very high95.7Very high37 Ų3739 Ų3926%0.25922%0.22SC..Hα-helixtrans-64.3-47.8178.2-170.20000112.4E229 T230 V231 I235 R236 I237E229-S233 VanDerWaalsContact O-CB 3.29Å; E229-S233 WeakPolarHBondContact O-CB 3.41Å; E229-S233 PolarHBondContact O-N 3.39Å; T230-S233 PolarHBondContact O-N 2.87Å; V231-S233 VanDerWaalsContact C-N 3.27Å; V231-S233 PolarHBondContact O-N 3.45Å; S233-I235 PolarHBondContact O-N 2.98Å; S233-R236 PolarHBondContact O-N 3.15Å; S233-I237 WeakPolarHBondContact O-CG1 3.37Å; S233-I237 PolarHBondContact O-N 2.74Å
234N97.1Very high96.2Very high1 Ų140.5 Ų40.51%0.00522%0.217CC..Hα-helixtrans-64.6-39.6-179.7-71.1-12.9000112L222 P223 T230 V231 R236 I237 L238 Y428L222-N234 HydrophobicContact CD2-CB 4.48Å; P223-N234 VanDerWaalsContact CD-OD1 3.22Å; P223-N234 WeakPolarHBondContact CD-OD1 3.16Å; P223-N234 WeakPolarHBondContact CG-OD1 3.26Å; P223-N234 PolarHBondContact O-ND2 2.88Å; T230-N234 WeakPolarHBondContact O-CB 3.43Å; T230-N234 VanDerWaalsContact O-CG 3.28Å; T230-N234 PolarHBondContact O-N 2.66Å; V231-N234 PolarHBondContact O-N 3.35Å; N234-R236 VanDerWaalsContact C-N 3.35Å; N234-R236 PolarHBondContact O-N 3.43Å; N234-I237 PolarHBondContact O-N 2.73Å; N234-L238 WeakPolarHBondContact O-CB 3.4Å; N234-L238 WeakPolarHBondContact O-CG 2.9Å; N234-L238 PolarHBondContact O-N 2.78Å; N234-Y428 HydrophobicContact CB-CD1 4.31Å; N234-Y428 HydrophobicContact CB-CE1 3.51Å; N234-Y428 HydrophobicContact CB-CE2 4.02Å; N234-Y428 WeakPolarHBondContact CB-OH 2.97Å; N234-Y428 PolarHBondContact ND2-OH 2.75Å; N234-Y428 VanDerWaalsContact ND2-OH 3.11Å
235I98.1Very high96.8Very high0 Ų036.2 Ų36.20%018%0.184CC..Hα-helixtrans-57.3-48.1173-72.8171.5000110.5V231 S233 F239 F425 Y428 Y429 L432 L447 L448 S451 F452V231-I235 HydrophobicContact CG1-CD1 3.84Å; V231-I235 HydrophobicContact CG1-CG1 4.44Å; V231-I235 WeakPolarHBondContact O-CG1 3.31Å; V231-I235 PolarHBondContact O-N 2.89Å; S233-I235 PolarHBondContact O-N 2.98Å; I235-F239 WeakPolarHBondContact O-CB 3.37Å; I235-F239 PolarHBondContact O-N 2.8Å; I235-F425 HydrophobicContact CG2-CE2 4.07Å; I235-F425 HydrophobicContact CG2-CZ 4.48Å; I235-Y428 HydrophobicContact CG1-CE1 4.13Å; I235-Y429 HydrophobicContact CD1-CD2 4.11Å; I235-Y429 HydrophobicContact CD1-CE2 3.93Å; I235-Y429 HydrophobicContact CG1-CD2 4.31Å; I235-L432 HydrophobicContact CD1-CD1 4.48Å; I235-L447 HydrophobicContact CD1-CD1 4.37Å; I235-L447 HydrophobicContact CD1-CD2 3.84Å; I235-L447 HydrophobicContact CD1-CG 3.77Å; I235-L448 HydrophobicContact CG2-CD1 4.13Å; I235-S451 WeakPolarHBondContact CD1-OG 3.24Å; I235-F452 HydrophobicContact CG2-CE2 4.24Å
236R97.9Very high97.3Very high59 Ų5934.5 Ų34.522%0.22317%0.165CC..Hα-helixtrans-60.9-50.6177.3-72-173.9-66.7-94.33.7112K232 S233 N234 L238 F239 E240 S451 F452K232-R236 WeakPolarHBondContact O-CG 2.98Å; K232-R236 PolarHBondContact O-N 3.44Å; S233-R236 PolarHBondContact O-N 3.15Å; N234-R236 VanDerWaalsContact C-N 3.35Å; N234-R236 PolarHBondContact O-N 3.43Å; R236-L238 PolarHBondContact O-N 2.95Å; R236-F239 PolarHBondContact O-N 2.96Å; R236-E240 WeakPolarHBondContact O-CB 3.12Å; R236-E240 VanDerWaalsContact O-CG 3.3Å; R236-E240 WeakPolarHBondContact O-CG 3.23Å; R236-E240 PolarHBondContact O-N 3.1Å; R236-S451 WeakPolarHBondContact CD-O 3.38Å; R236-S451 WeakPolarHBondContact CG-O 3.26Å; R236-S451 PolarHBondContact NH1-O 2.92Å; R236-F452 HydrophobicContact CB-CE1 4.43Å; R236-F452 HydrophobicContact CG-CD1 4.07Å; R236-F452 HydrophobicContact CG-CE1 3.85Å; R236-F452 HydrophobicContact CG-CZ 4.27Å
237I97.3Very high97.6Very high65 Ų6530.6 Ų30.633%0.33315%0.148SC..Hα-helixtrans-59-49.5-177.4-69.2165.3000110.7V219 L222 S233 N234 N241V219-I237 HydrophobicContact CG1-CG2 3.63Å; V219-I237 HydrophobicContact CG2-CG2 4.14Å; L222-I237 HydrophobicContact CD2-CG2 4.18Å; S233-I237 WeakPolarHBondContact O-CG1 3.37Å; S233-I237 PolarHBondContact O-N 2.74Å; N234-I237 PolarHBondContact O-N 2.73Å; I237-N241 WeakPolarHBondContact O-CB 3.17Å; I237-N241 PolarHBondContact O-N 3.48Å
238L97.4Very high97.7Very high2 Ų228 Ų281%0.0113%0.134CC..Hα-helixtrans-69.2-39.5-177.5-70.7175.1000112.2L222 N234 R236 N241 A242 R424 F425 Y428L222-L238 HydrophobicContact CD1-CD1 3.78Å; L222-L238 HydrophobicContact CD1-CD2 4.11Å; L222-L238 HydrophobicContact CD1-CG 4.1Å; L222-L238 HydrophobicContact CD2-CD2 4.32Å; L222-L238 HydrophobicContact CD2-CG 4.27Å; N234-L238 WeakPolarHBondContact O-CB 3.4Å; N234-L238 WeakPolarHBondContact O-CG 2.9Å; N234-L238 PolarHBondContact O-N 2.78Å; R236-L238 PolarHBondContact O-N 2.95Å; L238-N241 PolarHBondContact O-N 3.21Å; L238-A242 WeakPolarHBondContact O-CB 3.49Å; L238-A242 PolarHBondContact O-N 2.91Å; L238-R424 HydrophobicContact CD2-CB 4.2Å; L238-F425 HydrophobicContact CB-CB 4.39Å; L238-F425 HydrophobicContact CB-CD2 3.85Å; L238-Y428 HydrophobicContact CD1-CD1 3.65Å; L238-Y428 HydrophobicContact CD1-CD2 4.18Å; L238-Y428 HydrophobicContact CD1-CG 3.42Å; L238-Y428 VanDerWaalsContact CD1-CG 3.42Å
239F98.6Very high97.8Very high0 Ų026 Ų260%013%0.125CC..Hα-helixtrans-67.7-42.2176.9-170.3-107.5000111.9I235 R236 N241 A242 V243 L265 V266 V269 P419 F420 F425 F452I235-F239 WeakPolarHBondContact O-CB 3.37Å; I235-F239 PolarHBondContact O-N 2.8Å; R236-F239 PolarHBondContact O-N 2.96Å; F239-N241 VanDerWaalsContact C-N 3.31Å; F239-N241 PolarHBondContact O-N 2.79Å; F239-A242 WeakPolarHBondContact O-CB 3.48Å; F239-A242 PolarHBondContact O-N 2.98Å; F239-V243 HydrophobicContact CE1-CG2 4.27Å; F239-V243 HydrophobicContact CZ-CG2 4.42Å; F239-V243 WeakPolarHBondContact O-CG2 3.25Å; F239-V243 PolarHBondContact O-N 2.87Å; F239-L265 HydrophobicContact CE1-CB 4.23Å; F239-V266 HydrophobicContact CZ-CG2 3.81Å; F239-V269 HydrophobicContact CD1-CG2 4.12Å; F239-V269 HydrophobicContact CE1-CB 4.33Å; F239-V269 HydrophobicContact CE1-CG2 4.04Å; F239-P419 HydrophobicContact CE2-CB 4.39Å; F239-P419 HydrophobicContact CE2-CG 4.36Å; F239-P419 HydrophobicContact CZ-CG 4.45Å; F239-F420 HydrophobicContact CD2-CD1 4.32Å; F239-F420 HydrophobicContact CD2-CE1 4.16Å; F239-F420 HydrophobicContact CD2-CZ 4.43Å; F239-F420 AromaticContact CE2-CD1 3.76Å; F239-F420 HydrophobicContact CE2-CD1 3.76Å; F239-F420 AromaticContact CE2-CD2 3.78Å; F239-F420 HydrophobicContact CE2-CD2 3.78Å; F239-F420 AromaticContact CE2-CE1 3.56Å; F239-F420 HydrophobicContact CE2-CE1 3.56Å; F239-F420 AromaticContact CE2-CE2 3.61Å; F239-F420 HydrophobicContact CE2-CE2 3.61Å; F239-F420 AromaticContact CE2-CG 3.85Å; F239-F420 HydrophobicContact CE2-CG 3.85Å; F239-F420 AromaticContact CE2-CZ 3.48Å; F239-F420 HydrophobicContact CE2-CZ 3.48Å; F239-F420 VanDerWaalsContact CE2-CZ 3.48Å; F239-F420 HydrophobicContact CZ-CD2 4.16Å; F239-F420 HydrophobicContact CZ-CE1 4.13Å; F239-F420 AromaticContact CZ-CE2 3.61Å; F239-F420 HydrophobicContact CZ-CE2 3.61Å; F239-F420 AromaticContact CZ-CZ 3.58Å; F239-F420 HydrophobicContact CZ-CZ 3.58Å; F239-F425 HydrophobicContact CB-CD2 4.01Å; F239-F425 HydrophobicContact CB-CE2 3.74Å; F239-F425 HydrophobicContact CB-CZ 4.39Å; F239-F425 HydrophobicContact CD2-CD2 4.44Å; F239-F425 HydrophobicContact CD2-CE1 4.21Å; F239-F425 HydrophobicContact CD2-CE2 4.11Å; F239-F425 AromaticContact CD2-CZ 3.99Å; F239-F425 HydrophobicContact CD2-CZ 3.99Å; F239-F425 HydrophobicContact CG-CE2 4.37Å; F239-F452 HydrophobicContact CB-CZ 4.14Å; F239-F452 HydrophobicContact CD1-CE1 4.39Å; F239-F452 HydrophobicContact CD1-CE2 4.48Å; F239-F452 AromaticContact CD1-CZ 3.7Å; F239-F452 HydrophobicContact CD1-CZ 3.7Å; F239-F452 HydrophobicContact CE1-CZ 4.47Å; F239-F452 HydrophobicContact CG-CZ 4.17Å
240E98.2Very high97.8Very high36 Ų3626.8 Ų26.817%0.16813%0.128CC..Hα-helixtrans-61.5-40.3173.2-72.8-171.3-177.200111.3R236 V243 R244 V269 K272 L273R236-E240 WeakPolarHBondContact O-CB 3.12Å; R236-E240 VanDerWaalsContact O-CG 3.3Å; R236-E240 WeakPolarHBondContact O-CG 3.23Å; R236-E240 PolarHBondContact O-N 3.1Å; E240-V243 PolarHBondContact O-N 3.5Å; E240-R244 VanDerWaalsContact O-CB 3.25Å; E240-R244 WeakPolarHBondContact O-CB 3.41Å; E240-R244 PolarHBondContact O-N 2.89Å; E240-V269 HydrophobicContact CB-CG1 4.48Å; E240-V269 HydrophobicContact CG-CG1 3.96Å; E240-K272 IonicContact OE1-NZ 3.63Å; E240-K272 PolarHBondContact OE1-NZ 3.03Å; E240-K272 IonicContact OE2-NZ 2.87Å; E240-K272 PolarHBondContact OE2-NZ 3.1Å; E240-L273 VanDerWaalsContact O-CD1 3.31Å; E240-L273 WeakPolarHBondContact O-CD1 3.29Å
241N98Very high97.8Very high7 Ų728.6 Ų28.64%0.03713%0.132CC..Hα-helixtrans-65.1-41.3174.8-171.845.4000112.6D217 T218 V219 I237 L238 F239 V243 R244 K245D217-N241 PolarHBondContact OD1-ND2 3.01Å; D217-N241 PolarHBondContact OD2-ND2 2.8Å; T218-N241 PolarHBondContact OG1-OD1 3.22Å; V219-N241 HydrophobicContact CG2-CB 3.53Å; I237-N241 WeakPolarHBondContact O-CB 3.17Å; I237-N241 PolarHBondContact O-N 3.48Å; L238-N241 PolarHBondContact O-N 3.21Å; F239-N241 VanDerWaalsContact C-N 3.31Å; F239-N241 PolarHBondContact O-N 2.79Å; N241-V243 VanDerWaalsContact C-N 3.29Å; N241-V243 PolarHBondContact O-N 2.84Å; N241-R244 PolarHBondContact O-N 3.22Å; N241-K245 WeakPolarHBondContact ND2-CE 3.44Å; N241-K245 WeakPolarHBondContact O-CG 3.42Å; N241-K245 PolarHBondContact O-N 3.33Å
242A98.4Very high97.9Very high0 Ų030.4 Ų30.40%014%0.139CC..Hα-helixtrans-56.8-43.9175.500000111.4L238 F239 R246 P419 D422L238-A242 WeakPolarHBondContact O-CB 3.49Å; L238-A242 PolarHBondContact O-N 2.91Å; F239-A242 WeakPolarHBondContact O-CB 3.48Å; F239-A242 PolarHBondContact O-N 2.98Å; A242-R246 WeakPolarHBondContact O-CD 3.49Å; A242-R246 VanDerWaalsContact O-CG 3.3Å; A242-R246 WeakPolarHBondContact O-CG 3.39Å; A242-R246 PolarHBondContact O-NH1 2.5Å; A242-P419 HydrophobicContact CB-CB 4.09Å; A242-P419 WeakPolarHBondContact CB-O 3.33Å; A242-D422 HydrophobicContact CB-CB 3.4Å
243V98.8Very high97.9Very high0 Ų030.2 Ų30.20%014%0.138CC..Hα-helixtrans-71.5-42.2175.5-178.10000111.3F239 E240 N241 R246 L247 V269 L270 L273 F362 P419F239-V243 HydrophobicContact CE1-CG2 4.27Å; F239-V243 HydrophobicContact CZ-CG2 4.42Å; F239-V243 WeakPolarHBondContact O-CG2 3.25Å; F239-V243 PolarHBondContact O-N 2.87Å; E240-V243 PolarHBondContact O-N 3.5Å; N241-V243 VanDerWaalsContact C-N 3.29Å; N241-V243 PolarHBondContact O-N 2.84Å; V243-R246 CarbonylContact O-C 3.58Å; V243-R246 WeakPolarHBondContact O-CA 3.17Å; V243-R246 WeakPolarHBondContact O-CB 3.32Å; V243-R246 PolarHBondContact O-N 2.85Å; V243-R246 VanDerWaalsContact O-N 3.13Å; V243-L247 PolarHBondContact O-N 2.82Å; V243-V269 HydrophobicContact CB-CG1 3.9Å; V243-V269 HydrophobicContact CG1-CG1 4.15Å; V243-V269 HydrophobicContact CG2-CB 4.45Å; V243-V269 HydrophobicContact CG2-CG1 3.83Å; V243-L270 HydrophobicContact CG1-CB 4.06Å; V243-L270 HydrophobicContact CG1-CD1 4.01Å; V243-L273 HydrophobicContact CB-CD1 3.59Å; V243-L273 HydrophobicContact CG1-CD1 3.6Å; V243-F362 HydrophobicContact CG1-CE1 3.97Å; V243-P419 HydrophobicContact CG2-CB 3.69Å; V243-P419 HydrophobicContact CG2-CG 3.91Å
244R98.5Very high98Very high97 Ų9728.4 Ų28.437%0.36613%0.126SC..Hα-helixtrans-60.5-49.2-177.3-171.3-176.7-60.4-78.54.4112.3E240 N241 R246 L247 L273 E276E240-R244 VanDerWaalsContact O-CB 3.25Å; E240-R244 WeakPolarHBondContact O-CB 3.41Å; E240-R244 PolarHBondContact O-N 2.89Å; N241-R244 PolarHBondContact O-N 3.22Å; R244-R246 PolarHBondContact O-N 3.05Å; R244-L247 WeakPolarHBondContact O-CB 3.32Å; R244-L247 WeakPolarHBondContact O-CG 3.45Å; R244-L247 PolarHBondContact O-N 3.43Å; R244-L273 HydrophobicContact CB-CD1 4.06Å; R244-L273 HydrophobicContact CB-CD2 4.49Å; R244-E276 IonicContact CZ-OE2 3.32Å; R244-E276 VanDerWaalsContact CZ-OE2 3.24Å; R244-E276 IonicContact NH1-OE2 2.74Å; R244-E276 PolarHBondContact NH1-OE2 2.68Å; R244-E276 IonicContact NH2-OE2 3.53Å; R244-E276 PolarHBondContact NH2-OE2 3.21Å
245K97.9Very high98.1Very high23 Ų2328.4 Ų28.410%0.113%0.126CC..Hα-helixtrans-63.7-26.5178.874.6-18075.4167.60112.2Y79 D118 D217 N241 L247 D422Y79-K245 HydrophobicContact CD2-CD 4.34Å; Y79-K245 HydrophobicContact CD2-CG 4.44Å; Y79-K245 HydrophobicContact CG-CD 4.38Å; Y79-K245 HydrophobicContact CG-CG 4.16Å; D118-K245 IonicContact OD1-NZ 3.81Å; D118-K245 VanDerWaalsContact OD2-CD 3.28Å; D118-K245 WeakPolarHBondContact OD2-CD 3.38Å; D118-K245 WeakPolarHBondContact OD2-CE 3.33Å; D118-K245 IonicContact OD2-NZ 2.68Å; D118-K245 PolarHBondContact OD2-NZ 3.43Å; D217-K245 IonicContact OD2-NZ 3.24Å; D217-K245 PolarHBondContact OD2-NZ 3.11Å; N241-K245 WeakPolarHBondContact ND2-CE 3.44Å; N241-K245 WeakPolarHBondContact O-CG 3.42Å; N241-K245 PolarHBondContact O-N 3.33Å; K245-L247 VanDerWaalsContact C-N 3.29Å; K245-L247 PolarHBondContact O-N 3.36Å; K245-D422 WeakPolarHBondContact CD-OD2 3.11Å; K245-D422 VanDerWaalsContact CE-OD2 3.26Å; K245-D422 WeakPolarHBondContact CE-OD2 3.24Å; K245-D422 IonicContact NZ-OD1 3.73Å; K245-D422 PolarHBondContact NZ-OD1 3.08Å; K245-D422 IonicContact NZ-OD2 2.73Å; K245-D422 PolarHBondContact NZ-OD2 3.36Å
246R98.6Very high98.2Very high4 Ų429.3 Ų29.32%0.01513%0.13CC..THydrogen-bonded Turntrans-80.83.5174.5-73.1168.8-178.467.11.4113.7Y79 A242 V243 R244 M248 F362 R417 D422Y79-R246 HydrophobicContact CD1-CG 4.11Å; Y79-R246 HydrophobicContact CD2-CG 4.38Å; Y79-R246 HydrophobicContact CE1-CB 4.35Å; Y79-R246 HydrophobicContact CE1-CG 3.65Å; Y79-R246 HydrophobicContact CE2-CG 3.97Å; Y79-R246 HydrophobicContact CG-CG 4.46Å; A242-R246 WeakPolarHBondContact O-CD 3.49Å; A242-R246 VanDerWaalsContact O-CG 3.3Å; A242-R246 WeakPolarHBondContact O-CG 3.39Å; A242-R246 PolarHBondContact O-NH1 2.5Å; V243-R246 CarbonylContact O-C 3.58Å; V243-R246 WeakPolarHBondContact O-CA 3.17Å; V243-R246 WeakPolarHBondContact O-CB 3.32Å; V243-R246 PolarHBondContact O-N 2.85Å; V243-R246 VanDerWaalsContact O-N 3.13Å; R244-R246 PolarHBondContact O-N 3.05Å; R246-M248 PolarHBondContact O-N 3.34Å; R246-F362 HydrophobicContact CB-CE1 3.65Å; R246-F362 HydrophobicContact CB-CZ 3.6Å; R246-F362 WeakPolarHBondContact O-CZ 3.47Å; R246-R417 WeakPolarHBondContact O-CD 3.07Å; R246-R417 PolarHBondContact O-NH1 3.41Å; R246-D422 IonicContact CZ-OD2 2.76Å; R246-D422 IonicContact NH1-OD2 3.91Å; R246-D422 PolarHBondContact NH1-OD2 2.92Å; R246-D422 VanDerWaalsContact NH2-CA 3.32Å; R246-D422 IonicContact NH2-OD2 3.48Å; R246-D422 PolarHBondContact NH2-OD2 3.43Å
247L98.6Very high98.2Very high23 Ų2326.6 Ų26.612%0.1212%0.12CC..THydrogen-bonded Turntrans-75.6-6.1167.8-62.8-178.3000113.2V243 R244 K245 T249 I253 L270 L273 M274 A277V243-L247 PolarHBondContact O-N 2.82Å; R244-L247 WeakPolarHBondContact O-CB 3.32Å; R244-L247 WeakPolarHBondContact O-CG 3.45Å; R244-L247 PolarHBondContact O-N 3.43Å; K245-L247 VanDerWaalsContact C-N 3.29Å; K245-L247 PolarHBondContact O-N 3.36Å; L247-T249 PolarHBondContact O-N 3.26Å; L247-I253 HydrophobicContact CD2-CD1 3.88Å; L247-L270 HydrophobicContact CD2-CD1 3.49Å; L247-L270 VanDerWaalsContact CD2-CD1 3.49Å; L247-L273 HydrophobicContact CD1-CB 4.01Å; L247-M274 HydrophobicContact CD2-CG 4.08Å; L247-A277 HydrophobicContact CD1-CB 3.97Å
248M97.9Very high98.1Very high30 Ų3024.9 Ų24.915%0.14811%0.114CC..  trans-61.896.2-179.2179.4-178.290.900112.6V53 E77 Y79 F81 D97 R246 R417V53-M248 HydrophobicContact CG2-CE 4.27Å; V53-M248 HydrophobicContact CG2-CG 4.23Å; E77-M248 HydrophobicContact CB-CE 4.03Å; E77-M248 WeakPolarHBondContact OE2-CE 3.48Å; Y79-M248 HydrophobicContact CD1-CE 4.04Å; F81-M248 HydrophobicContact CD1-CE 4.44Å; F81-M248 HydrophobicContact CD1-SD 3.49Å; F81-M248 WeakPolarHBondContact CD1-SD 3.4Å; F81-M248 HydrophobicContact CE1-CG 4.18Å; F81-M248 HydrophobicContact CE1-SD 3.35Å; F81-M248 WeakPolarHBondContact CE1-SD 3.44Å; D97-M248 HydrophobicContact CB-CE 3.79Å; D97-M248 HydrophobicContact CB-SD 4.32Å; R246-M248 PolarHBondContact O-N 3.34Å; M248-R417 VanDerWaalsContact O-CZ 3.24Å; M248-R417 PolarHBondContact O-NH1 3.35Å; M248-R417 PolarHBondContact O-NH2 3.45Å
249T97.4Very high97.9Very high31 Ų3124.8 Ų24.819%0.1911%0.114CC..  trans-167.5158.3175.81790000111.5V52 L247 R251 I253 V360V52-T249 VanDerWaalsContact CG1-OG1 3.26Å; V52-T249 WeakPolarHBondContact CG1-OG1 3.28Å; V52-T249 PolarHBondContact O-OG1 3.3Å; L247-T249 PolarHBondContact O-N 3.26Å; T249-R251 VanDerWaalsContact CG2-O 3.25Å; T249-R251 WeakPolarHBondContact CG2-O 3.4Å; T249-R251 PolarHBondContact OG1-N 3.38Å; T249-R251 PolarHBondContact OG1-O 3.27Å; T249-I253 HydrophobicContact CG2-CD1 3.76Å; T249-I253 HydrophobicContact CG2-CG1 3.59Å; T249-V360 HydrophobicContact CG2-CG2 4.2Å
250H96.2Very high97.8Very high119 Ų11925.9 Ų25.955%0.55113%0.125SC*.SBendtrans-103.76.9165.6-59.389.9000112.5V52 D54V52-H250 PolarHBondContact O-N 3.33Å; D54-H250 PolarHBondContact N-ND1 3.07Å
251R97.5Very high97.8Very high63 Ų6324.5 Ų24.524%0.23812%0.118CC..SBendtrans-111.9158.5-180-59-66.1-70.9-876.5110.4D30 S51 T249 I253 V359 V360D30-R251 IonicContact OD2-NH1 3.89Å; D30-R251 PolarHBondContact OD2-NH1 2.99Å; S51-R251 VanDerWaalsContact O-CD 3.31Å; S51-R251 WeakPolarHBondContact O-CD 3.33Å; S51-R251 WeakPolarHBondContact O-CG 3.43Å; S51-R251 PolarHBondContact O-NH1 3.46Å; T249-R251 VanDerWaalsContact CG2-O 3.25Å; T249-R251 WeakPolarHBondContact CG2-O 3.4Å; T249-R251 PolarHBondContact OG1-N 3.38Å; T249-R251 PolarHBondContact OG1-O 3.27Å; R251-I253 PolarHBondContact O-N 3.14Å; R251-V359 HydrophobicContact CB-CB 4.03Å; R251-V359 HydrophobicContact CB-CG1 4.29Å; R251-V359 HydrophobicContact CG-CG1 4.41Å; R251-V360 HydrophobicContact CB-CG2 4.49Å
252R98.6Very high97.8Very high37 Ų3724.8 Ų24.814%0.1412%0.12CC..EExtended strand (participates in β ladder)trans-64.1134179.4-166.4177.9-176.3173.5-2.2110.8Y281 P282 Q284 E309 D357 V359 V360R252-Y281 HydrophobicContact CG-CD1 4.33Å; R252-Y281 HydrophobicContact CG-CD2 3.7Å; R252-Y281 HydrophobicContact CG-CE1 4.19Å; R252-Y281 HydrophobicContact CG-CE2 3.55Å; R252-Y281 HydrophobicContact CG-CG 4.11Å; R252-P282 PolarHBondContact NH2-O 3.31Å; R252-Q284 VanDerWaalsContact CZ-CD 3.41Å; R252-E309 IonicContact NH2-OE2 2.88Å; R252-E309 PolarHBondContact NH2-OE2 3.13Å; R252-D357 WeakPolarHBondContact CB-O 3.31Å; R252-D357 VanDerWaalsContact CD-CG 3.41Å; R252-D357 WeakPolarHBondContact CD-OD1 3.3Å; R252-D357 WeakPolarHBondContact CD-OD2 3.33Å; R252-D357 IonicContact CZ-OD1 3.45Å; R252-D357 IonicContact NE-OD1 2.82Å; R252-D357 IonicContact NH1-OD1 2.81Å; R252-D357 PolarHBondContact NH1-OD1 2.99Å; R252-D357 IonicContact NH1-OD2 3.14Å; R252-V359 PolarHBondContact O-N 3.34Å; R252-V360 PolarHBondContact O-N 3.37Å; R252-V360 VanDerWaalsContact O-N 3.15Å
253I98.9Very high97.8Very high0 Ų025.2 Ų25.20%012%0.123CC..EExtended strand (participates in β ladder)trans-91.9132.7175-60170.4000109.6L247 T249 R251 L270 Y281 L283 V360 F362L247-I253 HydrophobicContact CD2-CD1 3.88Å; T249-I253 HydrophobicContact CG2-CD1 3.76Å; T249-I253 HydrophobicContact CG2-CG1 3.59Å; R251-I253 PolarHBondContact O-N 3.14Å; I253-L270 HydrophobicContact CG2-CD1 4.19Å; I253-L270 HydrophobicContact CG2-CD2 3.91Å; I253-Y281 HydrophobicContact CB-CE2 4.49Å; I253-Y281 WeakPolarHBondContact CB-OH 3.32Å; I253-Y281 WeakPolarHBondContact CG1-OH 3.46Å; I253-Y281 PolarHBondContact N-OH 3.09Å; I253-L283 HydrophobicContact CG2-CD1 4.5Å; I253-V360 CarbonylContact C-O 3.58Å; I253-V360 WeakPolarHBondContact CA-O 3.4Å; I253-V360 HydrophobicContact CG1-CB 4.22Å; I253-V360 HydrophobicContact CG1-CG1 4.31Å; I253-F362 HydrophobicContact CD1-CE2 4.37Å; I253-F362 HydrophobicContact CG1-CE2 4.5Å; I253-F362 HydrophobicContact CG2-CD2 3.53Å; I253-F362 HydrophobicContact CG2-CE2 3.49Å; I253-F362 VanDerWaalsContact CG2-CE2 3.49Å
254G98.8Very high97.8Very high0 Ų025.2 Ų25.20%012%0.123CC..EExtended strand (participates in β ladder)trans-125.4176.6166.300000111.4Q284 V360 I361 F362G254-Q284 CarbonylContact C-O 3.51Å; G254-Q284 VanDerWaalsContact CA-O 3.28Å; G254-Q284 WeakPolarHBondContact CA-O 3.26Å; G254-V360 PolarHBondContact N-O 3.44Å; G254-I361 WeakPolarHBondContact O-CA 3.22Å; G254-F362 PolarHBondContact O-N 2.88Å
255C98.9Very high97.8Very high0 Ų020.6 Ų20.60%011%0.106CC..EExtended strand (participates in β ladder)trans-143136180-168.70000111.5L270 L283 Q284 T285 F286 F362C255-L270 HydrophobicContact CB-CD2 3.93Å; C255-L283 HydrophobicContact CB-CD1 4.26Å; C255-Q284 PolarHBondContact N-O 3.04Å; C255-T285 HydrophobicContact CB-CG2 4.33Å; C255-T285 CarbonylContact O-C 3.58Å; C255-T285 VanDerWaalsContact O-CA 3.26Å; C255-T285 WeakPolarHBondContact O-CA 3.34Å; C255-F286 PolarHBondContact O-N 2.59Å; C255-F362 WeakPolarHBondContact CA-O 3.11Å; C255-F362 HydrophobicContact CB-CB 4.26Å
256L98.8Very high97.8Very high19 Ų1919.5 Ų19.510%0.09910%0.101CC..EExtended strand (participates in β ladder)trans-71.5135.4164.6-60.1-176.9000108.9F286 M345 V348 I352 I361 F362L256-F286 HydrophobicContact CD2-CB 4.18Å; L256-M345 HydrophobicContact CD1-CE 3.56Å; L256-M345 HydrophobicContact CD1-CG 4.42Å; L256-V348 HydrophobicContact CD2-CG1 4.03Å; L256-V348 HydrophobicContact CD2-CG2 4.38Å; L256-I352 HydrophobicContact CD2-CD1 3.92Å; L256-I361 HydrophobicContact CD1-CG2 4.37Å; L256-I361 HydrophobicContact CD2-CG2 3.9Å; L256-I361 HydrophobicContact CG-CG2 3.64Å; L256-F362 PolarHBondContact N-O 2.86Å
257L98.4Very high97.8Very high2 Ų219.3 Ų19.31%0.0110%0.1CC..  trans-137.8100.9-177.7179.261.5000109.3A267 T285 F286 A287 A299 V302 A303L257-A267 HydrophobicContact CD1-CB 4.09Å; L257-T285 HydrophobicContact CB-CG2 4.41Å; L257-T285 HydrophobicContact CD2-CG2 4.12Å; L257-F286 PolarHBondContact N-O 2.93Å; L257-A287 WeakPolarHBondContact O-CA 3.38Å; L257-A287 WeakPolarHBondContact O-CB 3.44Å; L257-A299 HydrophobicContact CD2-CB 4.5Å; L257-A299 HydrophobicContact CG-CB 4.07Å; L257-A299 WeakPolarHBondContact O-CB 3.24Å; L257-V302 HydrophobicContact CD1-CB 4.13Å; L257-V302 HydrophobicContact CD1-CG1 3.78Å; L257-V302 HydrophobicContact CD2-CB 4.2Å; L257-V302 HydrophobicContact CD2-CG1 4.17Å; L257-A303 HydrophobicContact CD2-CB 3.97Å
258S95.7Very high97.8Very high30 Ų3018.4 Ų18.421%0.2110%0.096CC..  trans-89.2-10.7175.560.30000113.1G260 S263 D295S258-G260 PolarHBondContact O-N 3.48Å; S258-G260 PolarHBondContact OG-N 3.36Å; S258-S263 PolarHBondContact N-OG 3.3Å; S258-S263 VanDerWaalsContact N-OG 3.11Å; S258-S263 PolarHBondContact OG-OG 3.33Å; S258-D295 CarbonylContact O-C 3.4Å; S258-D295 VanDerWaalsContact O-CA 3.32Å; S258-D295 WeakPolarHBondContact O-CA 3.45Å; S258-D295 WeakPolarHBondContact O-CB 3.38Å; S258-D295 VanDerWaalsContact O-O 3.06Å
259G94.1Very high97.9Very high0 Ų017 Ų170%09%0.089CC..SBendtrans760.3-171.100000114.4S264G259-S264 WeakPolarHBondContact CA-OG 3.16Å
260G95.3Very high97.9Very high22 Ų2215.5 Ų15.523%0.2278%0.08CC..SBendtrans-69.4161.8162.700000111.6S258 D262 S263 S264S258-G260 PolarHBondContact O-N 3.48Å; S258-G260 PolarHBondContact OG-N 3.36Å; G260-D262 VanDerWaalsContact C-N 3.32Å; G260-D262 PolarHBondContact O-N 3.43Å; G260-S263 PolarHBondContact O-OG 3.4Å; G260-S264 WeakPolarHBondContact O-CB 3.27Å; G260-S264 PolarHBondContact O-N 3.1Å; G260-S264 VanDerWaalsContact O-N 3.14Å; G260-S264 PolarHBondContact O-OG 3.46Å
261L97.7Very high98.1Very high7 Ų710.6 Ų10.64%0.0376%0.058CC..Hα-helixtrans-49.6-50.3-175.5176.466000112.8S264 L265 K445 L448 R449 L458 L463L261-S264 PolarHBondContact O-N 3.18Å; L261-L265 HydrophobicContact CD1-CD1 3.86Å; L261-L265 HydrophobicContact CD1-CG 4.08Å; L261-L265 HydrophobicContact CG-CD1 4Å; L261-L265 HydrophobicContact CG-CG 4.5Å; L261-L265 WeakPolarHBondContact O-CG 3.49Å; L261-L265 PolarHBondContact O-N 3.05Å; L261-K445 HydrophobicContact CD2-CB 4.02Å; L261-K445 HydrophobicContact CD2-CD 3.86Å; L261-L448 HydrophobicContact CD2-CD2 3.99Å; L261-L448 HydrophobicContact CD2-CG 4.49Å; L261-R449 HydrophobicContact CD1-CG 4.18Å; L261-R449 HydrophobicContact CD2-CG 3.54Å; L261-L458 HydrophobicContact CD1-CD1 4.46Å; L261-L463 HydrophobicContact CD1-CD1 3.79Å
262D98.2Very high98.1Very high14 Ų1411 Ų118%0.0756%0.061CC..Hα-helixtrans-70.5-52.1-166.7-40.1-59.1000112.1G260 S264 L265 V266 S367 F420 K445G260-D262 VanDerWaalsContact C-N 3.32Å; G260-D262 PolarHBondContact O-N 3.43Å; D262-S264 PolarHBondContact O-N 2.53Å; D262-L265 PolarHBondContact O-N 3.36Å; D262-V266 WeakPolarHBondContact O-CG2 3.31Å; D262-V266 PolarHBondContact O-N 2.91Å; D262-S367 VanDerWaalsContact CG-OG 3.28Å; D262-S367 WeakPolarHBondContact OD1-CB 3.48Å; D262-S367 PolarHBondContact OD1-OG 3.48Å; D262-F420 HydrophobicContact CB-CE2 3.78Å; D262-F420 HydrophobicContact CB-CZ 4.14Å; D262-K445 IonicContact OD1-NZ 2.95Å; D262-K445 PolarHBondContact OD1-NZ 2.75Å; D262-K445 IonicContact OD2-NZ 3.95Å; D262-K445 PolarHBondContact OD2-NZ 3.01Å
263S98.1Very high98.1Very high9 Ų99.3 Ų9.36%0.0636%0.055CC..Hα-helixtrans-63-32.7177.963.10000111.5S258 G260 A267S258-S263 PolarHBondContact N-OG 3.3Å; S258-S263 VanDerWaalsContact N-OG 3.11Å; S258-S263 PolarHBondContact OG-OG 3.33Å; G260-S263 PolarHBondContact O-OG 3.4Å; S263-A267 WeakPolarHBondContact O-CB 3.45Å; S263-A267 PolarHBondContact O-N 3.46Å
264S98.7Very high98.1Very high0 Ų09.4 Ų9.40%06%0.056CC..Hα-helixtrans-67.6-46.3175.3-55.40000112G259 G260 L261 D262 V266 A267 A268 V302G259-S264 WeakPolarHBondContact CA-OG 3.16Å; G260-S264 WeakPolarHBondContact O-CB 3.27Å; G260-S264 PolarHBondContact O-N 3.1Å; G260-S264 VanDerWaalsContact O-N 3.14Å; G260-S264 PolarHBondContact O-OG 3.46Å; L261-S264 PolarHBondContact O-N 3.18Å; D262-S264 PolarHBondContact O-N 2.53Å; S264-V266 VanDerWaalsContact C-N 3.35Å; S264-V266 PolarHBondContact O-N 2.97Å; S264-A267 PolarHBondContact O-N 2.58Å; S264-A268 WeakPolarHBondContact O-CB 3.45Å; S264-A268 PolarHBondContact O-N 3.04Å; S264-V302 WeakPolarHBondContact OG-CG2 3.48Å
265L98.8Very high98Very high0 Ų015.9 Ų15.90%08%0.083CC..Hα-helixtrans-60.7-44.2175-76175.6000111.2F239 L261 D262 A268 V269 L448 F452 L458F239-L265 HydrophobicContact CE1-CB 4.23Å; L261-L265 HydrophobicContact CD1-CD1 3.86Å; L261-L265 HydrophobicContact CD1-CG 4.08Å; L261-L265 HydrophobicContact CG-CD1 4Å; L261-L265 HydrophobicContact CG-CG 4.5Å; L261-L265 WeakPolarHBondContact O-CG 3.49Å; L261-L265 PolarHBondContact O-N 3.05Å; D262-L265 PolarHBondContact O-N 3.36Å; L265-A268 PolarHBondContact O-N 3.29Å; L265-V269 WeakPolarHBondContact O-CB 3.46Å; L265-V269 VanDerWaalsContact O-CG2 3.3Å; L265-V269 WeakPolarHBondContact O-CG2 3.45Å; L265-V269 PolarHBondContact O-N 3.12Å; L265-L448 HydrophobicContact CD1-CD1 4.34Å; L265-L448 HydrophobicContact CD1-CD2 4.07Å; L265-L448 HydrophobicContact CD1-CG 4Å; L265-F452 HydrophobicContact CD1-CD2 3.78Å; L265-F452 HydrophobicContact CD1-CE2 4.02Å; L265-F452 HydrophobicContact CD2-CB 3.8Å; L265-F452 HydrophobicContact CD2-CD1 4.08Å; L265-F452 HydrophobicContact CD2-CD2 3.69Å; L265-F452 HydrophobicContact CD2-CE2 4.28Å; L265-F452 HydrophobicContact CD2-CG 3.58Å; L265-F452 HydrophobicContact CG-CD2 4.4Å; L265-L458 HydrophobicContact CD2-CD1 3.71Å; L265-L458 HydrophobicContact CD2-CG 4.36Å; L265-L458 HydrophobicContact CG-CD1 3.91Å
266V98.9Very high97.9Very high0 Ų020 Ų200%010%0.103CC..Hα-helixtrans-58.6-51.8175.4173.80000110.7F239 D262 S264 A268 L270 F362 P419 F420F239-V266 HydrophobicContact CZ-CG2 3.81Å; D262-V266 WeakPolarHBondContact O-CG2 3.31Å; D262-V266 PolarHBondContact O-N 2.91Å; S264-V266 VanDerWaalsContact C-N 3.35Å; S264-V266 PolarHBondContact O-N 2.97Å; V266-A268 PolarHBondContact O-N 3.15Å; V266-L270 WeakPolarHBondContact O-CB 3.23Å; V266-L270 PolarHBondContact O-N 3.41Å; V266-F362 HydrophobicContact CG1-CB 3.79Å; V266-F362 HydrophobicContact CG1-CD1 4.08Å; V266-F362 HydrophobicContact CG1-CG 4.42Å; V266-P419 HydrophobicContact CG1-CG 4.13Å; V266-P419 HydrophobicContact CG2-CG 3.72Å; V266-F420 HydrophobicContact CG2-CD2 4.06Å; V266-F420 HydrophobicContact CG2-CE2 3.71Å
267A98.9Very high97.9Very high0 Ų021.4 Ų21.40%012%0.117CC..Hα-helixtrans-62.3-42.4-17800000112.6L257 S263 S264 L271 T285 I306L257-A267 HydrophobicContact CD1-CB 4.09Å; S263-A267 WeakPolarHBondContact O-CB 3.45Å; S263-A267 PolarHBondContact O-N 3.46Å; S264-A267 PolarHBondContact O-N 2.58Å; A267-L271 WeakPolarHBondContact O-CB 3.4Å; A267-L271 PolarHBondContact O-N 2.88Å; A267-T285 HydrophobicContact CB-CG2 4.43Å; A267-I306 HydrophobicContact CB-CD1 3.94Å
268A98.8Very high97.8Very high4 Ų427.3 Ų27.33%0.03315%0.149CC..Hα-helixtrans-66.9-48-179.900000112.1S264 L265 V266 L271 K272 I306 L457 L458S264-A268 WeakPolarHBondContact O-CB 3.45Å; S264-A268 PolarHBondContact O-N 3.04Å; L265-A268 PolarHBondContact O-N 3.29Å; V266-A268 PolarHBondContact O-N 3.15Å; A268-L271 PolarHBondContact O-N 2.96Å; A268-K272 PolarHBondContact O-N 2.74Å; A268-K272 VanDerWaalsContact O-N 3.07Å; A268-I306 HydrophobicContact CB-CG2 3.92Å; A268-L457 HydrophobicContact CB-CB 4.05Å; A268-L457 HydrophobicContact CB-CD2 4.3Å; A268-L458 HydrophobicContact CB-CD2 3.95Å
269V98.8Very high97.9Very high0 Ų027.9 Ų27.90%015%0.149CC..Hα-helixtrans-65.1-42.2176.9172.30000110.5F239 E240 V243 L265 L271 K272 L273 F452 L457F239-V269 HydrophobicContact CD1-CG2 4.12Å; F239-V269 HydrophobicContact CE1-CB 4.33Å; F239-V269 HydrophobicContact CE1-CG2 4.04Å; E240-V269 HydrophobicContact CB-CG1 4.48Å; E240-V269 HydrophobicContact CG-CG1 3.96Å; V243-V269 HydrophobicContact CB-CG1 3.9Å; V243-V269 HydrophobicContact CG1-CG1 4.15Å; V243-V269 HydrophobicContact CG2-CB 4.45Å; V243-V269 HydrophobicContact CG2-CG1 3.83Å; L265-V269 WeakPolarHBondContact O-CB 3.46Å; L265-V269 VanDerWaalsContact O-CG2 3.3Å; L265-V269 WeakPolarHBondContact O-CG2 3.45Å; L265-V269 PolarHBondContact O-N 3.12Å; V269-L271 PolarHBondContact O-N 3.16Å; V269-K272 WeakPolarHBondContact O-CB 3.35Å; V269-K272 PolarHBondContact O-N 3.01Å; V269-L273 HydrophobicContact CG1-CD1 3.57Å; V269-L273 HydrophobicContact CG1-CG 4.14Å; V269-L273 WeakPolarHBondContact O-CB 3.16Å; V269-L273 WeakPolarHBondContact O-CG 3.39Å; V269-L273 PolarHBondContact O-N 2.85Å; V269-F452 HydrophobicContact CG2-CE1 4.44Å; V269-L457 HydrophobicContact CG2-CD1 3.85Å
270L98.8Very high97.9Very high0 Ų035.3 Ų35.30%019%0.189CC..Hα-helixtrans-57.5-48.9176.8177.261.3000111.5V243 L247 I253 C255 V266 K272 L273 M274 L283 F362V243-L270 HydrophobicContact CG1-CB 4.06Å; V243-L270 HydrophobicContact CG1-CD1 4.01Å; L247-L270 HydrophobicContact CD2-CD1 3.49Å; L247-L270 VanDerWaalsContact CD2-CD1 3.49Å; I253-L270 HydrophobicContact CG2-CD1 4.19Å; I253-L270 HydrophobicContact CG2-CD2 3.91Å; C255-L270 HydrophobicContact CB-CD2 3.93Å; V266-L270 WeakPolarHBondContact O-CB 3.23Å; V266-L270 PolarHBondContact O-N 3.41Å; L270-K272 PolarHBondContact O-N 2.72Å; L270-L273 PolarHBondContact O-N 3.24Å; L270-M274 HydrophobicContact CD1-CG 4.11Å; L270-M274 HydrophobicContact CD1-SD 4.13Å; L270-M274 HydrophobicContact CG-CG 4.38Å; L270-M274 HydrophobicContact CG-SD 3.92Å; L270-M274 WeakPolarHBondContact O-CB 3.38Å; L270-M274 VanDerWaalsContact O-CG 3.25Å; L270-M274 WeakPolarHBondContact O-CG 3.43Å; L270-M274 PolarHBondContact O-N 2.82Å; L270-L283 HydrophobicContact CD2-CD1 3.7Å; L270-L283 HydrophobicContact CD2-CD2 4.09Å; L270-L283 HydrophobicContact CG-CD1 4.31Å; L270-L283 HydrophobicContact CG-CD2 4.22Å; L270-F362 HydrophobicContact CD1-CD1 4.36Å; L270-F362 HydrophobicContact CD1-CD2 4.26Å; L270-F362 HydrophobicContact CD1-CE1 4.05Å; L270-F362 HydrophobicContact CD1-CE2 3.96Å; L270-F362 HydrophobicContact CD1-CG 4.43Å; L270-F362 HydrophobicContact CD1-CZ 3.81Å; L270-F362 HydrophobicContact CD2-CB 3.95Å; L270-F362 HydrophobicContact CD2-CD1 4.3Å; L270-F362 HydrophobicContact CD2-CD2 3.86Å; L270-F362 HydrophobicContact CD2-CE2 4.38Å; L270-F362 HydrophobicContact CD2-CG 3.79Å
271L98.5Very high98Very high16 Ų1637.5 Ų37.58%0.08419%0.191CC..Hα-helixtrans-64.3-40.4179.3-174.761.8000112.4A267 A268 V269 L273 M274 K275 L283 I306A267-L271 WeakPolarHBondContact O-CB 3.4Å; A267-L271 PolarHBondContact O-N 2.88Å; A268-L271 PolarHBondContact O-N 2.96Å; V269-L271 PolarHBondContact O-N 3.16Å; L271-L273 VanDerWaalsContact C-N 3.35Å; L271-M274 PolarHBondContact O-N 3.44Å; L271-K275 WeakPolarHBondContact O-CG 3.25Å; L271-K275 PolarHBondContact O-N 2.73Å; L271-K275 VanDerWaalsContact O-N 3.14Å; L271-L283 HydrophobicContact CB-CD2 3.92Å; L271-L283 HydrophobicContact CD1-CB 3.81Å; L271-L283 HydrophobicContact CD1-CD2 4.37Å; L271-I306 HydrophobicContact CD2-CB 3.91Å; L271-I306 HydrophobicContact CD2-CD1 4.48Å; L271-I306 HydrophobicContact CD2-CG1 4.08Å; L271-I306 WeakPolarHBondContact CD2-O 3.3Å
272K98.3Very high98Very high72 Ų7240.4 Ų40.431%0.31321%0.21SC..Hα-helixtrans-55.2-51.8173172.5-173.4165.9-172.50110.4E240 A268 V269 L270 K275 E276 L457E240-K272 IonicContact OE1-NZ 3.63Å; E240-K272 PolarHBondContact OE1-NZ 3.03Å; E240-K272 IonicContact OE2-NZ 2.87Å; E240-K272 PolarHBondContact OE2-NZ 3.1Å; A268-K272 PolarHBondContact O-N 2.74Å; A268-K272 VanDerWaalsContact O-N 3.07Å; V269-K272 WeakPolarHBondContact O-CB 3.35Å; V269-K272 PolarHBondContact O-N 3.01Å; L270-K272 PolarHBondContact O-N 2.72Å; K272-K275 WeakPolarHBondContact O-CB 3.34Å; K272-K275 PolarHBondContact O-N 3.18Å; K272-E276 WeakPolarHBondContact CE-OE1 2.94Å; K272-E276 PolarHBondContact O-N 3.33Å; K272-E276 VanDerWaalsContact O-N 3.11Å; K272-L457 HydrophobicContact CD-CD2 4.45Å
273L98.5Very high98Very high0 Ų039.8 Ų39.80%021%0.207CC..Hα-helixtrans-71.6-32.1-175.8-63173.6000113.1E240 V243 R244 L247 V269 L270 L271 K275 E276 A277E240-L273 VanDerWaalsContact O-CD1 3.31Å; E240-L273 WeakPolarHBondContact O-CD1 3.29Å; V243-L273 HydrophobicContact CB-CD1 3.59Å; V243-L273 HydrophobicContact CG1-CD1 3.6Å; R244-L273 HydrophobicContact CB-CD1 4.06Å; R244-L273 HydrophobicContact CB-CD2 4.49Å; L247-L273 HydrophobicContact CD1-CB 4.01Å; V269-L273 HydrophobicContact CG1-CD1 3.57Å; V269-L273 HydrophobicContact CG1-CG 4.14Å; V269-L273 WeakPolarHBondContact O-CB 3.16Å; V269-L273 WeakPolarHBondContact O-CG 3.39Å; V269-L273 PolarHBondContact O-N 2.85Å; L270-L273 PolarHBondContact O-N 3.24Å; L271-L273 VanDerWaalsContact C-N 3.35Å; L273-K275 VanDerWaalsContact C-N 3.32Å; L273-E276 WeakPolarHBondContact CD2-OE2 3.44Å; L273-E276 PolarHBondContact O-N 2.95Å; L273-A277 VanDerWaalsContact O-CB 3.29Å; L273-A277 WeakPolarHBondContact O-CB 3.23Å; L273-A277 PolarHBondContact O-N 3.46Å
274M98.4Very high98Very high3 Ų339.7 Ų39.72%0.01521%0.205CC..Hα-helixtrans-61.6-41.2171.7-76.9175.365.700111.5L247 L270 L271 A277 N278 I279 Y281 L283L247-M274 HydrophobicContact CD2-CG 4.08Å; L270-M274 HydrophobicContact CD1-CG 4.11Å; L270-M274 HydrophobicContact CD1-SD 4.13Å; L270-M274 HydrophobicContact CG-CG 4.38Å; L270-M274 HydrophobicContact CG-SD 3.92Å; L270-M274 WeakPolarHBondContact O-CB 3.38Å; L270-M274 VanDerWaalsContact O-CG 3.25Å; L270-M274 WeakPolarHBondContact O-CG 3.43Å; L270-M274 PolarHBondContact O-N 2.82Å; L271-M274 PolarHBondContact O-N 3.44Å; M274-A277 CarbonylContact O-C 3.05Å; M274-A277 PolarHBondContact O-N 2.97Å; M274-N278 PolarHBondContact O-N 2.98Å; M274-I279 HydrophobicContact CB-CB 4.21Å; M274-I279 HydrophobicContact CB-CD1 4.42Å; M274-I279 HydrophobicContact CE-CB 4.38Å; M274-I279 HydrophobicContact CE-CG2 3.75Å; M274-I279 HydrophobicContact CG-CD1 4.06Å; M274-I279 PolarHBondContact O-N 3.47Å; M274-Y281 HydrophobicContact CE-CD2 3.98Å; M274-Y281 HydrophobicContact CE-CE2 3.42Å; M274-Y281 VanDerWaalsContact CE-CE2 3.42Å; M274-L283 HydrophobicContact CE-CB 4.12Å; M274-L283 HydrophobicContact CE-CD1 4.46Å; M274-L283 HydrophobicContact SD-CB 4.02Å; M274-L283 HydrophobicContact SD-CD1 3.81Å; M274-L283 HydrophobicContact SD-CD2 4.45Å; M274-L283 HydrophobicContact SD-CG 4.29Å
275K97.4Very high98.1Very high135 Ų13539.7 Ų39.759%0.58721%0.205SC*.Hα-helixtrans-63.6-45.7174.5-70.2172.3-178.8174.90111.2L271 K272 L273 A277 N278L271-K275 WeakPolarHBondContact O-CG 3.25Å; L271-K275 PolarHBondContact O-N 2.73Å; L271-K275 VanDerWaalsContact O-N 3.14Å; K272-K275 WeakPolarHBondContact O-CB 3.34Å; K272-K275 PolarHBondContact O-N 3.18Å; L273-K275 VanDerWaalsContact C-N 3.32Å; K275-A277 VanDerWaalsContact C-N 3.27Å; K275-A277 PolarHBondContact O-N 2.9Å; K275-N278 PolarHBondContact O-N 3.2Å; K275-N278 VanDerWaalsContact O-N 3.1Å
276E97.7Very high98.1Very high88 Ų8839.8 Ų39.841%0.41121%0.206SC..Hα-helixtrans-61-35.4175.6-68.9174.3-164.400112.7R244 K272 L273 N278R244-E276 IonicContact CZ-OE2 3.32Å; R244-E276 VanDerWaalsContact CZ-OE2 3.24Å; R244-E276 IonicContact NH1-OE2 2.74Å; R244-E276 PolarHBondContact NH1-OE2 2.68Å; R244-E276 IonicContact NH2-OE2 3.53Å; R244-E276 PolarHBondContact NH2-OE2 3.21Å; K272-E276 WeakPolarHBondContact CE-OE1 2.94Å; K272-E276 PolarHBondContact O-N 3.33Å; K272-E276 VanDerWaalsContact O-N 3.11Å; L273-E276 WeakPolarHBondContact CD2-OE2 3.44Å; L273-E276 PolarHBondContact O-N 2.95Å; E276-N278 VanDerWaalsContact C-N 3.25Å; E276-N278 PolarHBondContact O-N 3.4Å
277A97.5Very high98Very high48 Ų4839.9 Ų39.940%0.39721%0.206SC..THydrogen-bonded Turntrans-823.6177.600000113.9L247 L273 M274 K275 I279L247-A277 HydrophobicContact CD1-CB 3.97Å; L273-A277 VanDerWaalsContact O-CB 3.29Å; L273-A277 WeakPolarHBondContact O-CB 3.23Å; L273-A277 PolarHBondContact O-N 3.46Å; M274-A277 CarbonylContact O-C 3.05Å; M274-A277 PolarHBondContact O-N 2.97Å; K275-A277 VanDerWaalsContact C-N 3.27Å; K275-A277 PolarHBondContact O-N 2.9Å; A277-I279 VanDerWaalsContact C-N 3.27Å; A277-I279 HydrophobicContact CB-CD1 4.14Å; A277-I279 HydrophobicContact CB-CG1 4.09Å; A277-I279 PolarHBondContact O-N 2.85Å
278N97.1Very high97.9Very high126 Ų12640.3 Ų40.367%0.67421%0.208SC*.THydrogen-bonded Turntrans54.438.9-176.2-57.8-67.3000113.7M274 K275 E276 N280M274-N278 PolarHBondContact O-N 2.98Å; K275-N278 PolarHBondContact O-N 3.2Å; K275-N278 VanDerWaalsContact O-N 3.1Å; E276-N278 VanDerWaalsContact C-N 3.25Å; E276-N278 PolarHBondContact O-N 3.4Å; N278-N280 PolarHBondContact O-N 2.77Å; N278-N280 PolarHBondContact O-ND2 3.33Å; N278-N280 PolarHBondContact O-OD1 2.95Å
279I97.5Very high97.7Very high42 Ų4240.1 Ų40.122%0.21521%0.207CC..  trans-81.1113.5173.6-63.1174.1000108.5M274 A277 Y281M274-I279 HydrophobicContact CB-CB 4.21Å; M274-I279 HydrophobicContact CB-CD1 4.42Å; M274-I279 HydrophobicContact CE-CB 4.38Å; M274-I279 HydrophobicContact CE-CG2 3.75Å; M274-I279 HydrophobicContact CG-CD1 4.06Å; M274-I279 PolarHBondContact O-N 3.47Å; A277-I279 VanDerWaalsContact C-N 3.27Å; A277-I279 HydrophobicContact CB-CD1 4.14Å; A277-I279 HydrophobicContact CB-CG1 4.09Å; A277-I279 PolarHBondContact O-N 2.85Å; I279-Y281 HydrophobicContact CG2-CD1 3.85Å; I279-Y281 HydrophobicContact CG2-CD2 4.24Å; I279-Y281 HydrophobicContact CG2-CE1 3.38Å; I279-Y281 HydrophobicContact CG2-CE2 3.81Å; I279-Y281 HydrophobicContact CG2-CG 4.24Å
280N93.3Very high97.4Very high156 Ų15640.7 Ų40.783%0.83421%0.21SC*.  trans-94.34.2-162.8-64.8-37.8000115.9N278N278-N280 PolarHBondContact O-N 2.77Å; N278-N280 PolarHBondContact O-ND2 3.33Å; N278-N280 PolarHBondContact O-OD1 2.95Å
281Y97.9Very high96.9Very high68 Ų6847.2 Ų47.227%0.26724%0.24SC..SBendtrans-96.2148.8170.557.3-105.7000110.4R252 I253 M274 I279R252-Y281 HydrophobicContact CG-CD1 4.33Å; R252-Y281 HydrophobicContact CG-CD2 3.7Å; R252-Y281 HydrophobicContact CG-CE1 4.19Å; R252-Y281 HydrophobicContact CG-CE2 3.55Å; R252-Y281 HydrophobicContact CG-CG 4.11Å; I253-Y281 HydrophobicContact CB-CE2 4.49Å; I253-Y281 WeakPolarHBondContact CB-OH 3.32Å; I253-Y281 WeakPolarHBondContact CG1-OH 3.46Å; I253-Y281 PolarHBondContact N-OH 3.09Å; M274-Y281 HydrophobicContact CE-CD2 3.98Å; M274-Y281 HydrophobicContact CE-CE2 3.42Å; M274-Y281 VanDerWaalsContact CE-CE2 3.42Å; I279-Y281 HydrophobicContact CG2-CD1 3.85Å; I279-Y281 HydrophobicContact CG2-CD2 4.24Å; I279-Y281 HydrophobicContact CG2-CE1 3.38Å; I279-Y281 HydrophobicContact CG2-CE2 3.81Å; I279-Y281 HydrophobicContact CG2-CG 4.24Å
282P97.8Very high96.3Very high68 Ų6850.4 Ų50.444%0.44226%0.257SS..PPolyproline II helixtrans-65.9137.5175.327.2-33.4000110.6R252 Q284 E309R252-P282 PolarHBondContact NH2-O 3.31Å; P282-Q284 PolarHBondContact O-N 3.37Å; P282-E309 HydrophobicContact CB-CB 4.1Å; P282-E309 HydrophobicContact CG-CB 4.44Å; P282-E309 VanDerWaalsContact CG-OE2 3.22Å; P282-E309 WeakPolarHBondContact CG-OE2 3.33Å
283L98.7Very high95.9Very high1 Ų147 Ų471%0.00524%0.243CC..PPolyproline II helixtrans-64.6117.7171.3175.862.2000108.6I253 C255 L270 L271 M274 T285 S308 E309I253-L283 HydrophobicContact CG2-CD1 4.5Å; C255-L283 HydrophobicContact CB-CD1 4.26Å; L270-L283 HydrophobicContact CD2-CD1 3.7Å; L270-L283 HydrophobicContact CD2-CD2 4.09Å; L270-L283 HydrophobicContact CG-CD1 4.31Å; L270-L283 HydrophobicContact CG-CD2 4.22Å; L271-L283 HydrophobicContact CB-CD2 3.92Å; L271-L283 HydrophobicContact CD1-CB 3.81Å; L271-L283 HydrophobicContact CD1-CD2 4.37Å; M274-L283 HydrophobicContact CE-CB 4.12Å; M274-L283 HydrophobicContact CE-CD1 4.46Å; M274-L283 HydrophobicContact SD-CB 4.02Å; M274-L283 HydrophobicContact SD-CD1 3.81Å; M274-L283 HydrophobicContact SD-CD2 4.45Å; M274-L283 HydrophobicContact SD-CG 4.29Å; L283-T285 HydrophobicContact CD2-CG2 4.18Å; L283-T285 HydrophobicContact CG-CG2 4.16Å; L283-S308 WeakPolarHBondContact O-CB 3.5Å; L283-E309 PolarHBondContact O-N 3.27Å
284Q98.9Very high95.5Very high7 Ų748.9 Ų48.93%0.03326%0.255CS..EExtended strand (participates in β ladder)trans-82.5125.7170.8-70.8174.6-31.400109.4R252 G254 C255 P282 F286 E309 S358R252-Q284 VanDerWaalsContact CZ-CD 3.41Å; G254-Q284 CarbonylContact C-O 3.51Å; G254-Q284 VanDerWaalsContact CA-O 3.28Å; G254-Q284 WeakPolarHBondContact CA-O 3.26Å; C255-Q284 PolarHBondContact N-O 3.04Å; P282-Q284 PolarHBondContact O-N 3.37Å; Q284-F286 HydrophobicContact CB-CE1 4.37Å; Q284-F286 HydrophobicContact CB-CE2 3.74Å; Q284-F286 HydrophobicContact CB-CZ 3.52Å; Q284-F286 HydrophobicContact CG-CZ 4.46Å; Q284-E309 VanDerWaalsContact CA-O 3.28Å; Q284-E309 WeakPolarHBondContact CA-O 3.4Å; Q284-E309 HydrophobicContact CG-CB 4.2Å; Q284-E309 HydrophobicContact CG-CG 4.29Å; Q284-E309 WeakPolarHBondContact CG-OE1 3.15Å; Q284-E309 PolarHBondContact NE2-OE1 2.99Å; Q284-S358 PolarHBondContact OE1-OG 2.78Å
285T98.9Very high95.1Very high0 Ų049 Ų490%026%0.256CS..EExtended strand (participates in β ladder)trans-113.2140.9174.953.60000110.2C255 L257 A267 L283 S308 E309 H310 H311C255-T285 HydrophobicContact CB-CG2 4.33Å; C255-T285 CarbonylContact O-C 3.58Å; C255-T285 VanDerWaalsContact O-CA 3.26Å; C255-T285 WeakPolarHBondContact O-CA 3.34Å; L257-T285 HydrophobicContact CB-CG2 4.41Å; L257-T285 HydrophobicContact CD2-CG2 4.12Å; A267-T285 HydrophobicContact CB-CG2 4.43Å; L283-T285 HydrophobicContact CD2-CG2 4.18Å; L283-T285 HydrophobicContact CG-CG2 4.16Å; T285-S308 WeakPolarHBondContact CG2-OG 3.37Å; T285-S308 WeakPolarHBondContact OG1-CB 3.49Å; T285-S308 PolarHBondContact OG1-OG 3.38Å; T285-E309 PolarHBondContact N-O 3.09Å; T285-H310 PolarHBondContact O-ND1 2.95Å; T285-H310 PolarHBondContact OG1-ND1 3.13Å; T285-H311 PolarHBondContact O-N 3.47Å
286F98.8Very high95Very high2 Ų242.6 Ų42.61%0.00923%0.228CC..EExtended strand (participates in β ladder)trans-125.8119.6-172.5-54-85000110.8C255 L256 L257 Q284 H311 V348 Y351 I352 T356 I361C255-F286 PolarHBondContact O-N 2.59Å; L256-F286 HydrophobicContact CD2-CB 4.18Å; L257-F286 PolarHBondContact N-O 2.93Å; Q284-F286 HydrophobicContact CB-CE1 4.37Å; Q284-F286 HydrophobicContact CB-CE2 3.74Å; Q284-F286 HydrophobicContact CB-CZ 3.52Å; Q284-F286 HydrophobicContact CG-CZ 4.46Å; F286-H311 WeakPolarHBondContact CA-O 3.44Å; F286-H311 HydrophobicContact CD1-CB 3.56Å; F286-H311 AromaticContact CD1-CG 3.94Å; F286-H311 HydrophobicContact CE1-CB 3.92Å; F286-H311 AromaticContact CE1-CD2 3.78Å; F286-H311 AromaticContact CE1-CG 3.74Å; F286-V348 HydrophobicContact CB-CG2 3.86Å; F286-Y351 HydrophobicContact CD1-CD1 4.5Å; F286-I352 HydrophobicContact CB-CD1 4.11Å; F286-I352 HydrophobicContact CB-CG1 4.3Å; F286-I352 HydrophobicContact CD1-CD1 4.23Å; F286-I352 HydrophobicContact CD1-CG1 3.54Å; F286-I352 HydrophobicContact CD2-CD1 3.73Å; F286-I352 HydrophobicContact CD2-CG1 3.81Å; F286-I352 HydrophobicContact CE1-CG1 3.71Å; F286-I352 HydrophobicContact CE2-CD1 4.19Å; F286-I352 HydrophobicContact CE2-CG1 3.95Å; F286-I352 HydrophobicContact CE2-CG2 4.42Å; F286-I352 HydrophobicContact CG-CD1 3.75Å; F286-I352 HydrophobicContact CG-CG1 3.6Å; F286-I352 HydrophobicContact CZ-CG1 3.9Å; F286-I352 HydrophobicContact CZ-CG2 4.27Å; F286-T356 HydrophobicContact CE1-CG2 3.71Å; F286-T356 HydrophobicContact CZ-CG2 3.9Å; F286-I361 HydrophobicContact CE2-CD1 4.4Å
287A98.2Very high94.9Very high2 Ų241.9 Ų41.92%0.01723%0.226CC..EExtended strand (participates in β ladder)trans-109.9145.1169.200000109L257 I296 A299 H311 V313L257-A287 WeakPolarHBondContact O-CA 3.38Å; L257-A287 WeakPolarHBondContact O-CB 3.44Å; A287-I296 HydrophobicContact CB-CD1 3.82Å; A287-A299 HydrophobicContact CB-CB 3.57Å; A287-H311 PolarHBondContact N-O 2.98Å; A287-V313 WeakPolarHBondContact O-CB 3.47Å; A287-V313 PolarHBondContact O-N 3.45Å
288I97.1Very high94.8Very high8 Ų839.7 Ų39.74%0.04121%0.208CC..EExtended strand (participates in β ladder)trans-128.2142170.4-176.4159.6000110V313 F315 G344 L347 V348 F470 I474I288-V313 VanDerWaalsContact CA-O 3.28Å; I288-V313 WeakPolarHBondContact CA-O 3.41Å; I288-V313 HydrophobicContact CB-CB 4.15Å; I288-V313 HydrophobicContact CD1-CB 4.37Å; I288-V313 HydrophobicContact CD1-CG1 3.95Å; I288-V313 HydrophobicContact CG1-CB 4.18Å; I288-V313 HydrophobicContact CG1-CG1 4.24Å; I288-V313 WeakPolarHBondContact CG1-O 3.43Å; I288-F315 HydrophobicContact CD1-CB 4.43Å; I288-F315 HydrophobicContact CD1-CD1 4.13Å; I288-F315 HydrophobicContact CG1-CD1 3.82Å; I288-F315 HydrophobicContact CG1-CE1 4.46Å; I288-G344 WeakPolarHBondContact CD1-O 3.19Å; I288-L347 HydrophobicContact CD1-CB 3.61Å; I288-V348 HydrophobicContact CB-CB 3.88Å; I288-V348 HydrophobicContact CB-CG2 4.14Å; I288-V348 HydrophobicContact CD1-CB 4.02Å; I288-V348 HydrophobicContact CG2-CB 3.85Å; I288-V348 HydrophobicContact CG2-CG1 4.16Å; I288-V348 HydrophobicContact CG2-CG2 4.36Å; I288-F470 HydrophobicContact CG2-CE2 4.47Å; I288-F470 HydrophobicContact CG2-CZ 3.86Å; I288-I474 VanDerWaalsContact O-CG2 3.26Å; I288-I474 WeakPolarHBondContact O-CG2 3.31Å
289G94.6Very high94.8Very high0 Ų033.7 Ų33.70%018%0.176CC..EExtended strand (participates in β ladder)trans-176.8172.6174.500000111.6V313 I314 F315G289-V313 PolarHBondContact N-O 3.42Å; G289-V313 VanDerWaalsContact N-O 3.1Å; G289-I314 WeakPolarHBondContact O-CA 3.2Å; G289-F315 PolarHBondContact O-N 2.94Å
290M91.3Very high94.9Very high12 Ų1236.1 Ų36.16%0.05918%0.182CC..SBendtrans-67.9161.5163-66-179.2174.600109.7N292 S293 F315 I474 W481 I484M290-N292 PolarHBondContact O-N 3.34Å; M290-S293 WeakPolarHBondContact O-CB 3.45Å; M290-S293 PolarHBondContact O-N 3.29Å; M290-S293 PolarHBondContact O-OG 2.87Å; M290-F315 HydrophobicContact CE-CE2 3.96Å; M290-F315 HydrophobicContact CE-CZ 3.96Å; M290-F315 HydrophobicContact CG-CE1 4.08Å; M290-F315 HydrophobicContact CG-CZ 4.05Å; M290-I474 WeakPolarHBondContact CB-O 3.14Å; M290-I474 WeakPolarHBondContact CG-O 3.48Å; M290-I474 PolarHBondContact N-O 3.42Å; M290-W481 HydrophobicContact CE-CB 4.2Å; M290-W481 HydrophobicContact CE-CD2 4.43Å; M290-W481 HydrophobicContact CE-CE3 3.73Å; M290-I484 HydrophobicContact CE-CD1 3.65Å; M290-I484 HydrophobicContact SD-CD1 4.05Å
291E88.2Confident95.1Very high138 Ų13833.6 Ų33.665%0.64516%0.164SC*.THydrogen-bonded Turntrans-54.2131-178.7-164-175.1175.700111.7S293 I314E291-S293 PolarHBondContact O-N 2.93Å; E291-I314 HydrophobicContact CB-CG2 4.17Å
292N86.6Confident95.1Very high83 Ų8330.4 Ų30.444%0.44415%0.152SC..THydrogen-bonded Turntrans5726.2-177.7-58.5-52.9000115M290M290-N292 PolarHBondContact O-N 3.34Å
293S90.5Very high95.2Very high0 Ų027.4 Ų27.40%013%0.133CC..  trans-63.5152.2173.9560000112.7M290 E291 D295 I296 L297 G473 T475M290-S293 WeakPolarHBondContact O-CB 3.45Å; M290-S293 PolarHBondContact O-N 3.29Å; M290-S293 PolarHBondContact O-OG 2.87Å; E291-S293 PolarHBondContact O-N 2.93Å; S293-D295 PolarHBondContact O-N 2.8Å; S293-I296 PolarHBondContact O-N 3.2Å; S293-I296 WeakPolarHBondContact OG-CG1 3.3Å; S293-L297 PolarHBondContact O-N 3.49Å; S293-L297 VanDerWaalsContact O-N 3.15Å; S293-G473 WeakPolarHBondContact CB-O 3.41Å; S293-T475 VanDerWaalsContact CA-O 3.23Å; S293-T475 WeakPolarHBondContact CA-O 3.19Å; S293-T475 WeakPolarHBondContact CB-O 3.28Å
294P89.3Confident95.1Very high40 Ų4032.6 Ų32.626%0.2616%0.164SC..Hα-helixtrans-54.2-37.8179.5-27.334.4000114.2A298 G473 T475P294-A298 WeakPolarHBondContact O-CB 3.25Å; P294-A298 PolarHBondContact O-N 3.36Å; P294-A298 VanDerWaalsContact O-N 3.08Å; P294-G473 WeakPolarHBondContact CD-O 3.37Å; P294-T475 HydrophobicContact CG-CG2 4.33Å
295D90.6Very high95.1Very high6 Ų635.9 Ų35.93%0.03218%0.18CC..Hα-helixtrans-70.4-42.1178.6-81.74.1000111.8S258 S293 L297 A298 A299 G473S258-D295 CarbonylContact O-C 3.4Å; S258-D295 VanDerWaalsContact O-CA 3.32Å; S258-D295 WeakPolarHBondContact O-CA 3.45Å; S258-D295 WeakPolarHBondContact O-CB 3.38Å; S258-D295 VanDerWaalsContact O-O 3.06Å; S293-D295 PolarHBondContact O-N 2.8Å; D295-L297 VanDerWaalsContact C-N 3.32Å; D295-L297 PolarHBondContact O-N 3.32Å; D295-A298 PolarHBondContact O-N 3.24Å; D295-A299 WeakPolarHBondContact O-CB 3.23Å; D295-A299 PolarHBondContact O-N 3.47Å; D295-G473 WeakPolarHBondContact CB-O 3.38Å; D295-G473 PolarHBondContact N-O 3.39Å
296I95Very high95.1Very high0 Ų036.9 Ų36.90%019%0.185CC..Hα-helixtrans-59.1-45.5176.3-70.6-71.1000110.7A287 S293 R300 E312 I314A287-I296 HydrophobicContact CB-CD1 3.82Å; S293-I296 PolarHBondContact O-N 3.2Å; S293-I296 WeakPolarHBondContact OG-CG1 3.3Å; I296-R300 WeakPolarHBondContact O-CB 3.4Å; I296-R300 PolarHBondContact O-N 3.11Å; I296-E312 HydrophobicContact CD1-CB 4.15Å; I296-E312 HydrophobicContact CD1-CG 4.3Å; I296-E312 HydrophobicContact CG2-CG 4.23Å; I296-E312 WeakPolarHBondContact CG2-OE2 3.46Å; I296-I314 HydrophobicContact CD1-CD1 4.09Å; I296-I314 HydrophobicContact CG1-CD1 4.22Å
297L94.9Very high95Very high73 Ų7339.6 Ų39.638%0.38221%0.214SC..Hα-helixtrans-65.3-40.6178.9-64.2178000112.2S293 D295 K301S293-L297 PolarHBondContact O-N 3.49Å; S293-L297 VanDerWaalsContact O-N 3.15Å; D295-L297 VanDerWaalsContact C-N 3.32Å; D295-L297 PolarHBondContact O-N 3.32Å; L297-K301 WeakPolarHBondContact O-CG 3.47Å; L297-K301 PolarHBondContact O-N 3.26Å
298A96.1Very high95.1Very high2 Ų240.3 Ų40.32%0.01722%0.219CC..Hα-helixtrans-67.9-46.4178.100000111.9P294 D295 R300 K301 V302 I462P294-A298 WeakPolarHBondContact O-CB 3.25Å; P294-A298 PolarHBondContact O-N 3.36Å; P294-A298 VanDerWaalsContact O-N 3.08Å; D295-A298 PolarHBondContact O-N 3.24Å; A298-R300 VanDerWaalsContact C-N 3.32Å; A298-R300 PolarHBondContact O-N 3.12Å; A298-K301 WeakPolarHBondContact O-CB 3.5Å; A298-K301 PolarHBondContact O-N 2.99Å; A298-K301 VanDerWaalsContact O-N 3.17Å; A298-V302 PolarHBondContact O-N 2.74Å; A298-V302 VanDerWaalsContact O-N 3.13Å; A298-I462 HydrophobicContact CB-CD1 4.17Å
299A97.7Very high95.1Very high0 Ų043.3 Ų43.30%023%0.232CC..Hα-helixtrans-58.8-43.7178.200000111.4L257 A287 D295 K301 V302 A303L257-A299 HydrophobicContact CD2-CB 4.5Å; L257-A299 HydrophobicContact CG-CB 4.07Å; L257-A299 WeakPolarHBondContact O-CB 3.24Å; A287-A299 HydrophobicContact CB-CB 3.57Å; D295-A299 WeakPolarHBondContact O-CB 3.23Å; D295-A299 PolarHBondContact O-N 3.47Å; A299-K301 VanDerWaalsContact C-N 3.31Å; A299-K301 PolarHBondContact O-N 3.14Å; A299-V302 PolarHBondContact O-N 2.83Å; A299-A303 VanDerWaalsContact O-CB 3.29Å; A299-A303 WeakPolarHBondContact O-CB 3.36Å; A299-A303 PolarHBondContact O-N 3.16Å
300R97.9Very high95.3Very high92 Ų9245.6 Ų45.635%0.34724%0.243SC..Hα-helixtrans-56.8-43175.7-170.6-174.8-62.4140.34.5112.6I296 A298 A303 T304 E312I296-R300 WeakPolarHBondContact O-CB 3.4Å; I296-R300 PolarHBondContact O-N 3.11Å; A298-R300 VanDerWaalsContact C-N 3.32Å; A298-R300 PolarHBondContact O-N 3.12Å; R300-A303 PolarHBondContact O-N 2.67Å; R300-T304 WeakPolarHBondContact O-CB 3.46Å; R300-T304 PolarHBondContact O-N 2.73Å; R300-T304 PolarHBondContact O-OG1 3.48Å; R300-E312 IonicContact CZ-OE1 3.5Å; R300-E312 VanDerWaalsContact CZ-OE1 3.31Å; R300-E312 IonicContact CZ-OE2 3.78Å; R300-E312 IonicContact NE-OE1 2.8Å; R300-E312 PolarHBondContact NE-OE1 3.17Å; R300-E312 IonicContact NE-OE2 3.01Å; R300-E312 VanDerWaalsContact NH2-CD 3.29Å; R300-E312 IonicContact NH2-OE1 2.9Å; R300-E312 PolarHBondContact NH2-OE1 2.88Å; R300-E312 VanDerWaalsContact NH2-OE1 3.14Å; R300-E312 IonicContact NH2-OE2 2.76Å; R300-E312 PolarHBondContact NH2-OE2 2.92Å
301K98.1Very high95.7Very high104 Ų10446.5 Ų46.545%0.45225%0.247SC..Hα-helixtrans-62.8-46.6177.8-71.3175.1169.1-163.60111.5L297 A298 A299 T304 H305 E461L297-K301 WeakPolarHBondContact O-CG 3.47Å; L297-K301 PolarHBondContact O-N 3.26Å; A298-K301 WeakPolarHBondContact O-CB 3.5Å; A298-K301 PolarHBondContact O-N 2.99Å; A298-K301 VanDerWaalsContact O-N 3.17Å; A299-K301 VanDerWaalsContact C-N 3.31Å; A299-K301 PolarHBondContact O-N 3.14Å; K301-T304 PolarHBondContact O-N 3.04Å; K301-H305 PolarHBondContact O-N 3.13Å; K301-E461 VanDerWaalsContact CD-OE1 3.25Å; K301-E461 WeakPolarHBondContact CD-OE1 3.45Å; K301-E461 WeakPolarHBondContact CE-OE1 3.43Å; K301-E461 IonicContact NZ-OE1 3.01Å; K301-E461 PolarHBondContact NZ-OE1 2.78Å
302V98.5Very high96.2Very high0 Ų043 Ų430%023%0.231CC..Hα-helixtrans-64.1-46.6178.2178.40000110.8L257 S264 A298 A299 T304 H305 I306 L458 I462L257-V302 HydrophobicContact CD1-CB 4.13Å; L257-V302 HydrophobicContact CD1-CG1 3.78Å; L257-V302 HydrophobicContact CD2-CB 4.2Å; L257-V302 HydrophobicContact CD2-CG1 4.17Å; S264-V302 WeakPolarHBondContact OG-CG2 3.48Å; A298-V302 PolarHBondContact O-N 2.74Å; A298-V302 VanDerWaalsContact O-N 3.13Å; A299-V302 PolarHBondContact O-N 2.83Å; V302-T304 VanDerWaalsContact C-N 3.28Å; V302-T304 PolarHBondContact O-N 2.89Å; V302-H305 WeakPolarHBondContact O-CB 3.43Å; V302-H305 PolarHBondContact O-N 3.09Å; V302-H305 VanDerWaalsContact O-N 3.11Å; V302-I306 HydrophobicContact CG1-CD1 4.48Å; V302-I306 HydrophobicContact CG1-CG2 4.35Å; V302-I306 WeakPolarHBondContact O-CG1 3.43Å; V302-I306 PolarHBondContact O-N 3.2Å; V302-L458 HydrophobicContact CG1-CD2 3.95Å; V302-I462 HydrophobicContact CG2-CB 4.22Å; V302-I462 HydrophobicContact CG2-CD1 4.1Å; V302-I462 HydrophobicContact CG2-CG1 3.74Å; V302-I462 HydrophobicContact CG2-CG2 3.71Å
303A98.6Very high96.7Very high5 Ų539.6 Ų39.64%0.04121%0.213CC..Hα-helixtrans-58.7-40.7178.400000112.4L257 A299 R300 G307 S308 H310L257-A303 HydrophobicContact CD2-CB 3.97Å; A299-A303 VanDerWaalsContact O-CB 3.29Å; A299-A303 WeakPolarHBondContact O-CB 3.36Å; A299-A303 PolarHBondContact O-N 3.16Å; R300-A303 PolarHBondContact O-N 2.67Å; A303-G307 WeakPolarHBondContact O-CA 3.39Å; A303-G307 PolarHBondContact O-N 2.94Å; A303-S308 WeakPolarHBondContact CA-OG 3.34Å; A303-S308 WeakPolarHBondContact CB-OG 3.49Å; A303-S308 PolarHBondContact O-N 3.45Å; A303-S308 VanDerWaalsContact O-N 3.16Å; A303-H310 HydrophobicContact CB-CB 3.65Å; A303-H310 VanDerWaalsContact CB-CG 3.43Å
304T98.4Very high97Very high110 Ų11043.5 Ų43.568%0.67523%0.233SC*.Hα-helixtrans-64.9-43.4174.8-56.50000111.3R300 K301 V302R300-T304 WeakPolarHBondContact O-CB 3.46Å; R300-T304 PolarHBondContact O-N 2.73Å; R300-T304 PolarHBondContact O-OG1 3.48Å; K301-T304 PolarHBondContact O-N 3.04Å; V302-T304 VanDerWaalsContact C-N 3.28Å; V302-T304 PolarHBondContact O-N 2.89Å
305H98.4Very high97.2Very high77 Ų7741.8 Ų41.836%0.35622%0.221SC..Hα-helixtrans-63.3-46.1178.9-176.889.8000112.4K301 V302 N456 L457 P459K301-H305 PolarHBondContact O-N 3.13Å; V302-H305 WeakPolarHBondContact O-CB 3.43Å; V302-H305 PolarHBondContact O-N 3.09Å; V302-H305 VanDerWaalsContact O-N 3.11Å; H305-N456 PolarHBondContact NE2-O 2.89Å; H305-L457 PolarHBondContact CD2-O 3.07Å; H305-P459 HydrophobicContact CB-CG 3.79Å
306I97.9Very high97.2Very high20 Ų2045.7 Ų45.710%0.10324%0.242CC..Hα-helixtrans-82.5-24-177.572.6-179.6000112.4A267 A268 L271 V302A267-I306 HydrophobicContact CB-CD1 3.94Å; A268-I306 HydrophobicContact CB-CG2 3.92Å; L271-I306 HydrophobicContact CD2-CB 3.91Å; L271-I306 HydrophobicContact CD2-CD1 4.48Å; L271-I306 HydrophobicContact CD2-CG1 4.08Å; L271-I306 WeakPolarHBondContact CD2-O 3.3Å; V302-I306 HydrophobicContact CG1-CD1 4.48Å; V302-I306 HydrophobicContact CG1-CG2 4.35Å; V302-I306 WeakPolarHBondContact O-CG1 3.43Å; V302-I306 PolarHBondContact O-N 3.2Å
307G97.9Very high97Very high60 Ų6048.2 Ų48.262%0.61926%0.26SS*.THydrogen-bonded Turntrans79.341.1-177.800000113.6A303A303-G307 WeakPolarHBondContact O-CA 3.39Å; A303-G307 PolarHBondContact O-N 2.94Å
308S98.5Very high97Very high17 Ų1750.5 Ų50.512%0.11927%0.268CS..  trans-83.8155.3175.359.90000112.5L283 T285 A303 H310L283-S308 WeakPolarHBondContact O-CB 3.5Å; T285-S308 WeakPolarHBondContact CG2-OG 3.37Å; T285-S308 WeakPolarHBondContact OG1-CB 3.49Å; T285-S308 PolarHBondContact OG1-OG 3.38Å; A303-S308 WeakPolarHBondContact CA-OG 3.34Å; A303-S308 WeakPolarHBondContact CB-OG 3.49Å; A303-S308 PolarHBondContact O-N 3.45Å; A303-S308 VanDerWaalsContact O-N 3.16Å; S308-H310 PolarHBondContact O-N 3.31Å
309E98.6Very high96.9Very high71 Ų7153.9 Ų53.933%0.33228%0.284SS..EExtended strand (participates in β ladder)trans-73.695.2166.9-173.6-165.2129.200108.7R252 P282 L283 Q284 T285 H311R252-E309 IonicContact NH2-OE2 2.88Å; R252-E309 PolarHBondContact NH2-OE2 3.13Å; P282-E309 HydrophobicContact CB-CB 4.1Å; P282-E309 HydrophobicContact CG-CB 4.44Å; P282-E309 VanDerWaalsContact CG-OE2 3.22Å; P282-E309 WeakPolarHBondContact CG-OE2 3.33Å; L283-E309 PolarHBondContact O-N 3.27Å; Q284-E309 VanDerWaalsContact CA-O 3.28Å; Q284-E309 WeakPolarHBondContact CA-O 3.4Å; Q284-E309 HydrophobicContact CG-CB 4.2Å; Q284-E309 HydrophobicContact CG-CG 4.29Å; Q284-E309 WeakPolarHBondContact CG-OE1 3.15Å; Q284-E309 PolarHBondContact NE2-OE1 2.99Å; T285-E309 PolarHBondContact N-O 3.09Å; E309-H311 PolarHBondContact O-CD2 3.06Å; E309-H311 IonicContact OE1-CE1 3.87Å; E309-H311 IonicContact OE1-NE2 3.88Å; E309-H311 PolarHBondContact OE1-NE2 2.96Å
310H98.7Very high96.8Very high48 Ų4853.9 Ų53.922%0.22228%0.284CS..EExtended strand (participates in β ladder)trans-90.1135.3-169.3-162.345.6000113.4T285 A303 S308 E312T285-H310 PolarHBondContact O-ND1 2.95Å; T285-H310 PolarHBondContact OG1-ND1 3.13Å; A303-H310 HydrophobicContact CB-CB 3.65Å; A303-H310 VanDerWaalsContact CB-CG 3.43Å; S308-H310 PolarHBondContact O-N 3.31Å; H310-E312 IonicContact CD2-OE1 2.72Å
311H98.7Very high96.7Very high31 Ų3151 Ų5114%0.14428%0.275CS..EExtended strand (participates in β ladder)trans-118.5115.3176.2-66.3-102.5000109.2T285 F286 A287 E309 Y351T285-H311 PolarHBondContact O-N 3.47Å; F286-H311 WeakPolarHBondContact CA-O 3.44Å; F286-H311 HydrophobicContact CD1-CB 3.56Å; F286-H311 AromaticContact CD1-CG 3.94Å; F286-H311 HydrophobicContact CE1-CB 3.92Å; F286-H311 AromaticContact CE1-CD2 3.78Å; F286-H311 AromaticContact CE1-CG 3.74Å; A287-H311 PolarHBondContact N-O 2.98Å; E309-H311 PolarHBondContact O-CD2 3.06Å; E309-H311 IonicContact OE1-CE1 3.87Å; E309-H311 IonicContact OE1-NE2 3.88Å; E309-H311 PolarHBondContact OE1-NE2 2.96Å; H311-Y351 HydrophobicContact CB-CE1 4.22Å; H311-Y351 AromaticContact ND1-CE1 3.87Å
312E98.2Very high96.7Very high64 Ų6452.2 Ų52.230%0.29928%0.282SS..EExtended strand (participates in β ladder)trans-96.9111.7172.3-68.5177.6-164.500109.4I296 R300 H310I296-E312 HydrophobicContact CD1-CB 4.15Å; I296-E312 HydrophobicContact CD1-CG 4.3Å; I296-E312 HydrophobicContact CG2-CG 4.23Å; I296-E312 WeakPolarHBondContact CG2-OE2 3.46Å; R300-E312 IonicContact CZ-OE1 3.5Å; R300-E312 VanDerWaalsContact CZ-OE1 3.31Å; R300-E312 IonicContact CZ-OE2 3.78Å; R300-E312 IonicContact NE-OE1 2.8Å; R300-E312 PolarHBondContact NE-OE1 3.17Å; R300-E312 IonicContact NE-OE2 3.01Å; R300-E312 VanDerWaalsContact NH2-CD 3.29Å; R300-E312 IonicContact NH2-OE1 2.9Å; R300-E312 PolarHBondContact NH2-OE1 2.88Å; R300-E312 VanDerWaalsContact NH2-OE1 3.14Å; R300-E312 IonicContact NH2-OE2 2.76Å; R300-E312 PolarHBondContact NH2-OE2 2.92Å; H310-E312 IonicContact CD2-OE1 2.72Å
313V97.6Very high96.6Very high12 Ų1252.6 Ų52.67%0.07329%0.285CS..EExtended strand (participates in β ladder)trans-95.8111.9179.9-174.10000108.3A287 I288 G289 V348 Y351A287-V313 WeakPolarHBondContact O-CB 3.47Å; A287-V313 PolarHBondContact O-N 3.45Å; I288-V313 VanDerWaalsContact CA-O 3.28Å; I288-V313 WeakPolarHBondContact CA-O 3.41Å; I288-V313 HydrophobicContact CB-CB 4.15Å; I288-V313 HydrophobicContact CD1-CB 4.37Å; I288-V313 HydrophobicContact CD1-CG1 3.95Å; I288-V313 HydrophobicContact CG1-CB 4.18Å; I288-V313 HydrophobicContact CG1-CG1 4.24Å; I288-V313 WeakPolarHBondContact CG1-O 3.43Å; G289-V313 PolarHBondContact N-O 3.42Å; G289-V313 VanDerWaalsContact N-O 3.1Å; V313-V348 HydrophobicContact CG2-CG2 4.07Å; V313-Y351 HydrophobicContact CG1-CD2 3.96Å; V313-Y351 HydrophobicContact CG1-CG 4.11Å; V313-Y351 HydrophobicContact CG2-CD1 3.61Å; V313-Y351 HydrophobicContact CG2-CD2 3.86Å; V313-Y351 HydrophobicContact CG2-CE1 3.99Å; V313-Y351 HydrophobicContact CG2-CE2 4.17Å; V313-Y351 HydrophobicContact CG2-CG 3.56Å
314I96.4Very high96.6Very high81 Ų8152.4 Ų52.442%0.41528%0.284SS..EExtended strand (participates in β ladder)trans-96.5122.3176.7-52.7-54.6000109G289 E291 I296G289-I314 WeakPolarHBondContact O-CA 3.2Å; E291-I314 HydrophobicContact CB-CG2 4.17Å; I296-I314 HydrophobicContact CD1-CD1 4.09Å; I296-I314 HydrophobicContact CG1-CD1 4.22Å
315F93.5Very high96.6Very high5 Ų550.8 Ų50.82%0.02227%0.269CS..  trans-110.8151.2171.882.1-77.2000110.3I288 G289 M290 L347 I474 W481I288-F315 HydrophobicContact CD1-CB 4.43Å; I288-F315 HydrophobicContact CD1-CD1 4.13Å; I288-F315 HydrophobicContact CG1-CD1 3.82Å; I288-F315 HydrophobicContact CG1-CE1 4.46Å; G289-F315 PolarHBondContact O-N 2.94Å; M290-F315 HydrophobicContact CE-CE2 3.96Å; M290-F315 HydrophobicContact CE-CZ 3.96Å; M290-F315 HydrophobicContact CG-CE1 4.08Å; M290-F315 HydrophobicContact CG-CZ 4.05Å; F315-L347 HydrophobicContact CB-CD1 3.89Å; F315-L347 HydrophobicContact CD2-CD1 3.94Å; F315-L347 HydrophobicContact CG-CD1 4.03Å; F315-I474 HydrophobicContact CE1-CB 4.25Å; F315-I474 HydrophobicContact CE1-CD1 4.09Å; F315-I474 HydrophobicContact CE1-CG1 4.47Å; F315-I474 HydrophobicContact CZ-CD1 3.93Å; F315-I474 HydrophobicContact CZ-CG1 4.47Å; F315-W481 HydrophobicContact CE2-CD2 4.48Å; F315-W481 HydrophobicContact CE2-CE3 4.29Å
316N91.6Very high96.6Very high88 Ų8851.7 Ų51.747%0.47127%0.273SS..  trans-103167.8175.171.848.3000111.4E318 E319 G320N316-E318 VanDerWaalsContact C-N 3.31Å; N316-E318 PolarHBondContact O-N 3.41Å; N316-E318 WeakPolarHBondContact OD1-CB 3.41Å; N316-E318 PolarHBondContact OD1-N 3.48Å; N316-E319 PolarHBondContact O-N 2.89Å; N316-E319 PolarHBondContact OD1-N 3.15Å; N316-G320 PolarHBondContact O-N 2.7Å
317S91.3Very high96.6Very high53 Ų5350.8 Ų50.837%0.37127%0.268SS..Hα-helixtrans-60.2-38.2-17848.10000113.8G320 I321S317-G320 PolarHBondContact O-N 3Å; S317-I321 VanDerWaalsContact O-CG1 3.3Å; S317-I321 WeakPolarHBondContact O-CG1 3.47Å; S317-I321 PolarHBondContact O-N 3.38Å
318E93.7Very high96.7Very high120 Ų12047.9 Ų47.956%0.56124%0.239SC*.Hα-helixtrans-67.5-45.4-179.1-176.3-177.8172.800110.8N316 G320 I321 Q322N316-E318 VanDerWaalsContact C-N 3.31Å; N316-E318 PolarHBondContact O-N 3.41Å; N316-E318 WeakPolarHBondContact OD1-CB 3.41Å; N316-E318 PolarHBondContact OD1-N 3.48Å; E318-G320 VanDerWaalsContact C-N 3.31Å; E318-G320 PolarHBondContact O-N 3.46Å; E318-I321 PolarHBondContact O-N 3.27Å; E318-Q322 HydrophobicContact CG-CG 4.41Å; E318-Q322 WeakPolarHBondContact O-CB 3.37Å; E318-Q322 VanDerWaalsContact O-CG 3.29Å; E318-Q322 WeakPolarHBondContact O-CG 3.38Å; E318-Q322 PolarHBondContact O-N 2.71Å; E318-Q322 PolarHBondContact OE1-NE2 3.49Å
319E95.4Very high96.7Very high74 Ų7450.7 Ų50.735%0.34625%0.249SC..Hα-helixtrans-59.1-43.2174.9-176.7177.7-160.700111.3N316 A323 L347N316-E319 PolarHBondContact O-N 2.89Å; N316-E319 PolarHBondContact OD1-N 3.15Å; E319-A323 WeakPolarHBondContact O-CB 3.45Å; E319-A323 PolarHBondContact O-N 3.16Å; E319-A323 VanDerWaalsContact O-N 3.08Å; E319-L347 HydrophobicContact CG-CD1 4.03Å; E319-L347 HydrophobicContact CG-CD2 3.95Å
320G94.8Very high96.7Very high0 Ų047.8 Ų47.80%024%0.236CC..Hα-helixtrans-62.2-44176.400000113N316 S317 E318 A323 W481N316-G320 PolarHBondContact O-N 2.7Å; S317-G320 PolarHBondContact O-N 3Å; E318-G320 VanDerWaalsContact C-N 3.31Å; E318-G320 PolarHBondContact O-N 3.46Å; G320-A323 PolarHBondContact O-N 2.83Å; G320-W481 VanDerWaalsContact C-CH2 3.42Å
321I96.1Very high96.7Very high31 Ų3145.5 Ų45.516%0.15923%0.226CC..Hα-helixtrans-68.1-45.1179.3-71164.4000110.7S317 E318 A323 L324 W481 I484 Y488S317-I321 VanDerWaalsContact O-CG1 3.3Å; S317-I321 WeakPolarHBondContact O-CG1 3.47Å; S317-I321 PolarHBondContact O-N 3.38Å; E318-I321 PolarHBondContact O-N 3.27Å; I321-A323 PolarHBondContact O-N 2.85Å; I321-L324 HydrophobicContact CG2-CD1 4.5Å; I321-L324 WeakPolarHBondContact O-CB 3.09Å; I321-L324 WeakPolarHBondContact O-CG 2.98Å; I321-L324 PolarHBondContact O-N 3.26Å; I321-L324 VanDerWaalsContact O-N 3.11Å; I321-W481 HydrophobicContact CG1-CH2 4.12Å; I321-W481 HydrophobicContact CG1-CZ3 4.21Å; I321-I484 HydrophobicContact CD1-CG2 4.08Å; I321-Y488 HydrophobicContact CD1-CD2 4.2Å; I321-Y488 HydrophobicContact CD1-CG 3.95Å; I321-Y488 HydrophobicContact CG1-CD1 4.45Å; I321-Y488 HydrophobicContact CG1-CG 4.36Å; I321-Y488 HydrophobicContact CG2-CD1 3.79Å; I321-Y488 HydrophobicContact CG2-CD2 4Å; I321-Y488 HydrophobicContact CG2-CE1 3.56Å; I321-Y488 HydrophobicContact CG2-CE2 3.8Å; I321-Y488 HydrophobicContact CG2-CG 4Å
322Q96.9Very high96.7Very high129 Ų12944.2 Ų44.260%0.60322%0.22SC*.Hα-helixtrans-62.1-29178.5-74.2173.9-0.800112.4E318 L324E318-Q322 HydrophobicContact CG-CG 4.41Å; E318-Q322 WeakPolarHBondContact O-CB 3.37Å; E318-Q322 VanDerWaalsContact O-CG 3.29Å; E318-Q322 WeakPolarHBondContact O-CG 3.38Å; E318-Q322 PolarHBondContact O-N 2.71Å; E318-Q322 PolarHBondContact OE1-NE2 3.49Å; Q322-L324 VanDerWaalsContact C-N 3.33Å
323A97.8Very high96.7Very high8 Ų841.4 Ų41.47%0.06621%0.207CC..THydrogen-bonded Turntrans-75.6-15.2177.600000114.2E319 G320 I321 E325 E326 V327 V343 L347E319-A323 WeakPolarHBondContact O-CB 3.45Å; E319-A323 PolarHBondContact O-N 3.16Å; E319-A323 VanDerWaalsContact O-N 3.08Å; G320-A323 PolarHBondContact O-N 2.83Å; I321-A323 PolarHBondContact O-N 2.85Å; A323-E325 VanDerWaalsContact C-N 3.34Å; A323-E325 PolarHBondContact O-N 3.29Å; A323-E326 PolarHBondContact O-N 3.24Å; A323-V327 HydrophobicContact CB-CG2 4.26Å; A323-V327 VanDerWaalsContact O-CB 3.32Å; A323-V327 WeakPolarHBondContact O-CB 3.48Å; A323-V327 WeakPolarHBondContact O-CG2 3.5Å; A323-V327 PolarHBondContact O-N 2.82Å; A323-V343 HydrophobicContact CB-CG1 4.46Å; A323-L347 HydrophobicContact CB-CD2 4.24Å
324L98.1Very high96.7Very high1 Ų140.9 Ų40.91%0.00520%0.204CC..Hα-helixtrans-56.3-43.8-172.2-75.6169.8000113.3I321 Q322 V327 I328 V339 V343 L485 Y517 Y518I321-L324 HydrophobicContact CG2-CD1 4.5Å; I321-L324 WeakPolarHBondContact O-CB 3.09Å; I321-L324 WeakPolarHBondContact O-CG 2.98Å; I321-L324 PolarHBondContact O-N 3.26Å; I321-L324 VanDerWaalsContact O-N 3.11Å; Q322-L324 VanDerWaalsContact C-N 3.33Å; L324-V327 PolarHBondContact O-N 3.14Å; L324-I328 WeakPolarHBondContact O-CG1 3.12Å; L324-I328 PolarHBondContact O-N 3.34Å; L324-V339 HydrophobicContact CD2-CG1 4.01Å; L324-V343 HydrophobicContact CD2-CG2 3.77Å; L324-L485 HydrophobicContact CD1-CD2 3.79Å; L324-L485 HydrophobicContact CD2-CD2 4.23Å; L324-L485 HydrophobicContact CG-CD2 4.49Å; L324-Y517 HydrophobicContact CD1-CE1 4.13Å; L324-Y518 HydrophobicContact CD2-CE1 3.98Å
325E98.3Very high96.7Very high77 Ų7737 Ų3736%0.3618%0.184SC..Hα-helixtrans-64.9-49.8-179.5-175.4170.1157.300111.6A323 V327 I328 F329 I521 K524 H525A323-E325 VanDerWaalsContact C-N 3.34Å; A323-E325 PolarHBondContact O-N 3.29Å; E325-V327 VanDerWaalsContact C-N 3.27Å; E325-V327 PolarHBondContact O-N 3.36Å; E325-I328 PolarHBondContact O-N 2.82Å; E325-F329 WeakPolarHBondContact O-CB 3.29Å; E325-F329 PolarHBondContact O-N 2.89Å; E325-I521 HydrophobicContact CB-CG2 4.38Å; E325-I521 HydrophobicContact CG-CG2 4.11Å; E325-K524 IonicContact OE1-NZ 2.8Å; E325-K524 PolarHBondContact OE1-NZ 2.88Å; E325-K524 IonicContact OE2-NZ 3.69Å; E325-K524 PolarHBondContact OE2-NZ 3.41Å; E325-H525 VanDerWaalsContact CG-NE2 3.26Å; E325-H525 WeakPolarHBondContact CG-NE2 3.47Å; E325-H525 IonicContact OE1-CE1 2.74Å; E325-H525 PolarHBondContact OE1-CE1 2.9Å; E325-H525 IonicContact OE1-NE2 3.19Å; E325-H525 PolarHBondContact OE1-NE2 3.2Å
326E98.4Very high96.8Very high96 Ų9637.2 Ų37.245%0.44919%0.185SC..Hα-helixtrans-62.4-35.3177-69.1-174.6-167.600112.3A323 S330 Y346A323-E326 PolarHBondContact O-N 3.24Å; E326-S330 WeakPolarHBondContact O-CB 3.31Å; E326-S330 PolarHBondContact O-N 3.08Å; E326-S330 PolarHBondContact O-OG 3.46Å; E326-Y346 HydrophobicContact CB-CE1 4.42Å; E326-Y346 PolarHBondContact OE2-OH 3.33Å
327V98.8Very high96.7Very high0 Ų034.4 Ų34.40%017%0.171CC..Hα-helixtrans-66.5-50.5177166.90000110.3A323 L324 E325 F329 S330 L331 V343 Y346A323-V327 HydrophobicContact CB-CG2 4.26Å; A323-V327 VanDerWaalsContact O-CB 3.32Å; A323-V327 WeakPolarHBondContact O-CB 3.48Å; A323-V327 WeakPolarHBondContact O-CG2 3.5Å; A323-V327 PolarHBondContact O-N 2.82Å; L324-V327 PolarHBondContact O-N 3.14Å; E325-V327 VanDerWaalsContact C-N 3.27Å; E325-V327 PolarHBondContact O-N 3.36Å; V327-F329 VanDerWaalsContact C-N 3.32Å; V327-F329 PolarHBondContact O-N 2.96Å; V327-S330 PolarHBondContact O-N 3.37Å; V327-S330 VanDerWaalsContact O-N 3.09Å; V327-L331 HydrophobicContact CG1-CD1 3.61Å; V327-L331 HydrophobicContact CG1-CG 4.15Å; V327-L331 WeakPolarHBondContact O-CB 3.4Å; V327-L331 WeakPolarHBondContact O-CG 3.44Å; V327-L331 PolarHBondContact O-N 2.87Å; V327-V343 HydrophobicContact CG1-CG2 4.38Å; V327-V343 HydrophobicContact CG2-CG2 4.29Å; V327-Y346 HydrophobicContact CG2-CD1 3.94Å; V327-Y346 HydrophobicContact CG2-CD2 4.2Å; V327-Y346 HydrophobicContact CG2-CG 3.72Å
328I98.8Very high97Very high0 Ų032.1 Ų32.10%016%0.155CC..Hα-helixtrans-63.5-39.8178.8-70166.6000110.9L324 E325 S330 L331 E332 V339 Y518 I521 F522L324-I328 WeakPolarHBondContact O-CG1 3.12Å; L324-I328 PolarHBondContact O-N 3.34Å; E325-I328 PolarHBondContact O-N 2.82Å; I328-S330 VanDerWaalsContact C-N 3.35Å; I328-S330 PolarHBondContact O-N 3.37Å; I328-L331 PolarHBondContact O-N 3.09Å; I328-E332 PolarHBondContact O-N 2.76Å; I328-V339 HydrophobicContact CD1-CG1 4.15Å; I328-V339 HydrophobicContact CD1-CG2 4.42Å; I328-V339 HydrophobicContact CG1-CG1 3.98Å; I328-V339 HydrophobicContact CG1-CG2 3.84Å; I328-Y518 HydrophobicContact CD1-CD1 3.86Å; I328-Y518 HydrophobicContact CD1-CG 4.17Å; I328-I521 HydrophobicContact CB-CG2 3.81Å; I328-I521 HydrophobicContact CD1-CB 3.84Å; I328-I521 HydrophobicContact CD1-CD1 3.84Å; I328-I521 HydrophobicContact CD1-CG1 4.44Å; I328-I521 HydrophobicContact CD1-CG2 3.79Å; I328-I521 HydrophobicContact CG1-CG2 4.4Å; I328-I521 HydrophobicContact CG2-CB 4.33Å; I328-I521 HydrophobicContact CG2-CG2 3.75Å; I328-F522 HydrophobicContact CG2-CB 4.04Å
329F98.6Very high97.1Very high76 Ų7626.4 Ų26.433%0.33313%0.128SC..Hα-helixtrans-58.5-44.7170.8174.5-97.4000112K162 E325 V327 H525 Y526K162-F329 HydrophobicContact CD-CE1 4.03Å; K162-F329 HydrophobicContact CD-CZ 3.83Å; K162-F329 WeakPolarHBondContact CE-O 3.41Å; K162-F329 PolarHBondContact NZ-O 2.91Å; E325-F329 WeakPolarHBondContact O-CB 3.29Å; E325-F329 PolarHBondContact O-N 2.89Å; V327-F329 VanDerWaalsContact C-N 3.32Å; V327-F329 PolarHBondContact O-N 2.96Å; F329-H525 HydrophobicContact CD2-CB 4.23Å; F329-H525 AromaticContact CD2-CG 3.95Å; F329-H525 AromaticContact CD2-ND1 3.76Å; F329-Y526 VanDerWaalsContact CD2-OH 3.24Å; F329-Y526 WeakPolarHBondContact CD2-OH 3.43Å; F329-Y526 WeakPolarHBondContact CE2-OH 3.46Å; F329-Y526 PolarHBondContact O-OH 2.84Å
330S98.7Very high97Very high9 Ų923.1 Ų23.16%0.06311%0.113CC..Hα-helixtrans-67.2-42.2179.8-61.10000111.9K162 E326 V327 I328 R407K162-S330 PolarHBondContact NZ-O 3.04Å; E326-S330 WeakPolarHBondContact O-CB 3.31Å; E326-S330 PolarHBondContact O-N 3.08Å; E326-S330 PolarHBondContact O-OG 3.46Å; V327-S330 PolarHBondContact O-N 3.37Å; V327-S330 VanDerWaalsContact O-N 3.09Å; I328-S330 VanDerWaalsContact C-N 3.35Å; I328-S330 PolarHBondContact O-N 3.37Å; S330-R407 WeakPolarHBondContact O-CB 3.18Å; S330-R407 WeakPolarHBondContact O-CD 3.36Å; S330-R407 WeakPolarHBondContact O-CG 3.16Å
331L98.8Very high96.9Very high0 Ų023.4 Ų23.40%012%0.115CC..Hα-helixtrans-70.6-38.9-176.4-72173.5000113.8V327 I328 T333 T338 V339 S342 L403 R404 R407 T408V327-L331 HydrophobicContact CG1-CD1 3.61Å; V327-L331 HydrophobicContact CG1-CG 4.15Å; V327-L331 WeakPolarHBondContact O-CB 3.4Å; V327-L331 WeakPolarHBondContact O-CG 3.44Å; V327-L331 PolarHBondContact O-N 2.87Å; I328-L331 PolarHBondContact O-N 3.09Å; L331-T333 VanDerWaalsContact C-N 3.28Å; L331-T333 HydrophobicContact CB-CG2 4Å; L331-T338 HydrophobicContact CD1-CG2 4.34Å; L331-T338 HydrophobicContact CD2-CG2 4.24Å; L331-V339 HydrophobicContact CD1-CG2 4.02Å; L331-S342 WeakPolarHBondContact CD1-OG 3.44Å; L331-S342 VanDerWaalsContact CD2-OG 3.29Å; L331-S342 WeakPolarHBondContact CD2-OG 3.17Å; L331-L403 HydrophobicContact CB-CD2 4.03Å; L331-L403 HydrophobicContact CD2-CD2 3.52Å; L331-L403 HydrophobicContact CG-CD2 4.36Å; L331-L403 WeakPolarHBondContact O-CD2 3.39Å; L331-R404 HydrophobicContact CD2-CB 4.35Å; L331-R407 HydrophobicContact CD2-CB 4.18Å; L331-T408 HydrophobicContact CD2-CG2 4.21Å
332E98.6Very high97Very high5 Ų522 Ų222%0.02311%0.108CC..THydrogen-bonded Turntrans63.733.4-172.6-46.2173.4147.600112.4E160 A161 K162 I328 R407 F522 Y526 W532E160-E332 WeakPolarHBondContact CB-OE1 3.49Å; A161-E332 VanDerWaalsContact N-CD 3.32Å; A161-E332 PolarHBondContact N-OE1 3.15Å; A161-E332 PolarHBondContact N-OE2 3.48Å; K162-E332 VanDerWaalsContact CB-OE1 3.23Å; K162-E332 WeakPolarHBondContact CB-OE1 3.37Å; K162-E332 WeakPolarHBondContact CE-OE1 3.32Å; K162-E332 VanDerWaalsContact CG-OE1 3.27Å; K162-E332 WeakPolarHBondContact CG-OE1 3.48Å; K162-E332 PolarHBondContact N-OE1 3.34Å; K162-E332 VanDerWaalsContact NZ-CD 3.27Å; K162-E332 IonicContact NZ-OE1 3.32Å; K162-E332 PolarHBondContact NZ-OE1 2.98Å; I328-E332 PolarHBondContact O-N 2.76Å; E332-R407 IonicContact OE2-NE 2.66Å; E332-F522 WeakPolarHBondContact O-CE2 3.03Å; E332-Y526 HydrophobicContact CB-CE2 4.19Å; E332-Y526 HydrophobicContact CG-CE2 4.02Å; E332-W532 HydrophobicContact CB-CE3 4.09Å; E332-W532 HydrophobicContact CB-CZ3 4Å
333T98.6Very high97Very high4 Ų415.8 Ų15.83%0.0258%0.079CC..  trans-148.1163.8173.8-174.40000111.1L331 D335 T338 L403L331-T333 VanDerWaalsContact C-N 3.28Å; L331-T333 HydrophobicContact CB-CG2 4Å; T333-D335 PolarHBondContact OG1-N 3.01Å; T333-T338 HydrophobicContact CG2-CG2 3.95Å; T333-L403 HydrophobicContact CG2-CD1 4.35Å; T333-L403 HydrophobicContact CG2-CD2 3.83Å
334Y97.8Very high97Very high1 Ų115.4 Ų15.40%0.0048%0.076CC..  trans-120.715178.655.1-87.9000112.5I336 N508 R519 F522 S530 L533 F536Y334-I336 PolarHBondContact O-N 3.46Å; Y334-N508 HydrophobicContact CE2-CB 4.18Å; Y334-N508 VanDerWaalsContact OH-CB 3.28Å; Y334-N508 WeakPolarHBondContact OH-CB 3.45Å; Y334-R519 HydrophobicContact CD2-CB 4.46Å; Y334-F522 HydrophobicContact CD1-CB 4.2Å; Y334-F522 AromaticContact CD1-CD1 3.65Å; Y334-F522 HydrophobicContact CD1-CD1 3.65Å; Y334-F522 AromaticContact CD1-CD2 3.93Å; Y334-F522 HydrophobicContact CD1-CD2 3.93Å; Y334-F522 AromaticContact CD1-CE1 3.99Å; Y334-F522 HydrophobicContact CD1-CE1 3.99Å; Y334-F522 HydrophobicContact CD1-CE2 4.22Å; Y334-F522 AromaticContact CD1-CG 3.63Å; Y334-F522 HydrophobicContact CD1-CG 3.63Å; Y334-F522 HydrophobicContact CD1-CZ 4.25Å; Y334-F522 HydrophobicContact CE1-CD1 4.18Å; Y334-F522 HydrophobicContact CE1-CE1 4.13Å; Y334-F522 HydrophobicContact CE1-CZ 4.43Å; Y334-F522 HydrophobicContact CG-CB 4.43Å; Y334-F522 HydrophobicContact CG-CG 4.34Å; Y334-S530 PolarHBondContact OH-O 3.25Å; Y334-S530 VanDerWaalsContact OH-O 3.08Å; Y334-L533 HydrophobicContact CD2-CD2 4.09Å; Y334-L533 HydrophobicContact CE1-CB 4.03Å; Y334-L533 HydrophobicContact CE1-CD2 4.27Å; Y334-L533 HydrophobicContact CE2-CD2 3.81Å; Y334-L533 HydrophobicContact CG-CD2 4.45Å; Y334-F536 AromaticContact CD2-CE1 3.77Å; Y334-F536 HydrophobicContact CD2-CE1 3.77Å; Y334-F536 AromaticContact CD2-CZ 3.66Å; Y334-F536 HydrophobicContact CD2-CZ 3.66Å; Y334-F536 HydrophobicContact CE2-CE1 4.01Å; Y334-F536 HydrophobicContact CE2-CE2 4.2Å; Y334-F536 AromaticContact CE2-CZ 3.57Å; Y334-F536 HydrophobicContact CE2-CZ 3.57Å
335D97.4Very high97Very high0 Ų015.5 Ų15.50%08%0.076CC..  trans-63.5130.4175.8176.372.8000111.9T333 T337 T338 V339 F400 L533 F536 W537T333-D335 PolarHBondContact OG1-N 3.01Å; D335-T337 PolarHBondContact OD2-N 3.07Å; D335-T338 PolarHBondContact O-N 3.38Å; D335-T338 VanDerWaalsContact OD2-CB 3.29Å; D335-T338 WeakPolarHBondContact OD2-CB 3.47Å; D335-T338 PolarHBondContact OD2-N 2.81Å; D335-T338 PolarHBondContact OD2-OG1 2.87Å; D335-V339 WeakPolarHBondContact O-CB 3.25Å; D335-V339 VanDerWaalsContact O-CG2 3.27Å; D335-V339 WeakPolarHBondContact O-CG2 3.36Å; D335-V339 PolarHBondContact O-N 3.28Å; D335-F400 HydrophobicContact CB-CD1 4.47Å; D335-F400 HydrophobicContact CB-CE1 4.39Å; D335-L533 HydrophobicContact CB-CD1 4.41Å; D335-L533 HydrophobicContact CB-CD2 3.83Å; D335-F536 WeakPolarHBondContact OD1-CA 3.09Å; D335-W537 PolarHBondContact OD1-N 2.81Å
336I93.9Very high97Very high9 Ų912.7 Ų12.75%0.0466%0.062CC..Hα-helixtrans-60.7-52.4-173.8-64.6161.3000111.5Y334 T338 V339 R340 E514 P547Y334-I336 PolarHBondContact O-N 3.46Å; I336-T338 VanDerWaalsContact C-N 3.29Å; I336-T338 PolarHBondContact O-N 2.84Å; I336-V339 PolarHBondContact O-N 3.46Å; I336-R340 HydrophobicContact CG2-CG 4.33Å; I336-R340 WeakPolarHBondContact O-CB 3.29Å; I336-R340 VanDerWaalsContact O-CG 3.32Å; I336-R340 WeakPolarHBondContact O-CG 3.44Å; I336-R340 PolarHBondContact O-N 2.72Å; I336-E514 HydrophobicContact CG2-CG 4.46Å; I336-P547 HydrophobicContact CB-CG 3.99Å; I336-P547 HydrophobicContact CD1-CG 4.49Å; I336-P547 HydrophobicContact CG2-CG 4.09Å
337T91.2Very high97Very high30 Ų308.5 Ų8.518%0.1844%0.043CC..Hα-helixtrans-60.4-45.1-176.8-58.60000110.7D335 A341 W537 P547D335-T337 PolarHBondContact OD2-N 3.07Å; T337-A341 WeakPolarHBondContact O-CB 3.21Å; T337-A341 PolarHBondContact O-N 3.46Å; T337-A341 VanDerWaalsContact O-N 3.15Å; T337-W537 HydrophobicContact CG2-CE3 4.31Å; T337-P547 WeakPolarHBondContact OG1-CB 3.43Å; T337-P547 WeakPolarHBondContact OG1-CG 3.24Å
338T96Very high97Very high4 Ų48.7 Ų8.73%0.0254%0.044CC..Hα-helixtrans-62.8-50.4-179.5-540000110.6L331 T333 D335 I336 A341 S342 L403 R404L331-T338 HydrophobicContact CD1-CG2 4.34Å; L331-T338 HydrophobicContact CD2-CG2 4.24Å; T333-T338 HydrophobicContact CG2-CG2 3.95Å; D335-T338 PolarHBondContact O-N 3.38Å; D335-T338 VanDerWaalsContact OD2-CB 3.29Å; D335-T338 WeakPolarHBondContact OD2-CB 3.47Å; D335-T338 PolarHBondContact OD2-N 2.81Å; D335-T338 PolarHBondContact OD2-OG1 2.87Å; I336-T338 VanDerWaalsContact C-N 3.29Å; I336-T338 PolarHBondContact O-N 2.84Å; T338-A341 PolarHBondContact O-N 2.9Å; T338-S342 WeakPolarHBondContact O-CB 3.43Å; T338-S342 PolarHBondContact O-N 2.96Å; T338-S342 PolarHBondContact O-OG 2.76Å; T338-L403 HydrophobicContact CG2-CD2 4.08Å; T338-R404 HydrophobicContact CG2-CB 4.02Å
339V97.1Very high97Very high0 Ų08.7 Ų8.70%04%0.044CC..Hα-helixtrans-62.5-48.6-179.3173.10000111.3L324 I328 L331 D335 I336 A341 S342 V343 Y518L324-V339 HydrophobicContact CD2-CG1 4.01Å; I328-V339 HydrophobicContact CD1-CG1 4.15Å; I328-V339 HydrophobicContact CD1-CG2 4.42Å; I328-V339 HydrophobicContact CG1-CG1 3.98Å; I328-V339 HydrophobicContact CG1-CG2 3.84Å; L331-V339 HydrophobicContact CD1-CG2 4.02Å; D335-V339 WeakPolarHBondContact O-CB 3.25Å; D335-V339 VanDerWaalsContact O-CG2 3.27Å; D335-V339 WeakPolarHBondContact O-CG2 3.36Å; D335-V339 PolarHBondContact O-N 3.28Å; I336-V339 PolarHBondContact O-N 3.46Å; V339-A341 VanDerWaalsContact C-N 3.35Å; V339-A341 PolarHBondContact O-N 2.87Å; V339-S342 PolarHBondContact O-N 2.9Å; V339-S342 VanDerWaalsContact O-N 3.12Å; V339-V343 PolarHBondContact O-N 3.48Å; V339-Y518 HydrophobicContact CB-CD2 3.86Å; V339-Y518 HydrophobicContact CB-CE2 3.71Å; V339-Y518 HydrophobicContact CB-CG 4.44Å; V339-Y518 HydrophobicContact CG1-CD1 4.08Å; V339-Y518 HydrophobicContact CG1-CD2 3.91Å; V339-Y518 HydrophobicContact CG1-CE1 3.82Å; V339-Y518 HydrophobicContact CG1-CE2 3.6Å; V339-Y518 HydrophobicContact CG1-CG 4.13Å; V339-Y518 HydrophobicContact CG2-CD2 4.12Å; V339-Y518 HydrophobicContact CG2-CE2 4.48Å; V339-Y518 HydrophobicContact CG2-CG 4.44Å
340R93.1Very high97Very high5 Ų59.4 Ų9.42%0.0195%0.047CC..Hα-helixtrans-54.9-48.4179.6-74.8176.5-179.6160.45112.3I336 S342 W481 L485 E514 D546I336-R340 HydrophobicContact CG2-CG 4.33Å; I336-R340 WeakPolarHBondContact O-CB 3.29Å; I336-R340 VanDerWaalsContact O-CG 3.32Å; I336-R340 WeakPolarHBondContact O-CG 3.44Å; I336-R340 PolarHBondContact O-N 2.72Å; R340-S342 VanDerWaalsContact C-N 3.34Å; R340-W481 PolarHBondContact O-NE1 3.21Å; R340-L485 HydrophobicContact CG-CD1 4.06Å; R340-E514 WeakPolarHBondContact CG-OE1 3.31Å; R340-E514 IonicContact CZ-OE1 2.85Å; R340-E514 IonicContact CZ-OE2 2.82Å; R340-E514 IonicContact NE-OE1 3.41Å; R340-E514 PolarHBondContact NE-OE1 3.3Å; R340-E514 IonicContact NE-OE2 2.65Å; R340-E514 PolarHBondContact NE-OE2 3.44Å; R340-E514 VanDerWaalsContact NH2-CD 3.32Å; R340-E514 IonicContact NH2-OE1 3.32Å; R340-E514 PolarHBondContact NH2-OE1 2.99Å; R340-E514 IonicContact NH2-OE2 2.76Å; R340-E514 PolarHBondContact NH2-OE2 3.1Å; R340-D546 IonicContact CZ-OD1 3.14Å; R340-D546 IonicContact CZ-OD2 3.31Å; R340-D546 IonicContact NH1-OD1 2.68Å; R340-D546 PolarHBondContact NH1-OD1 3.02Å; R340-D546 IonicContact NH1-OD2 3.62Å; R340-D546 IonicContact NH2-OD1 3.49Å; R340-D546 PolarHBondContact NH2-OD1 3.13Å; R340-D546 IonicContact NH2-OD2 3.6Å; R340-D546 PolarHBondContact NH2-OD2 3.03Å
341A92.7Very high97Very high7 Ų712.3 Ų12.36%0.0586%0.057CC..Hα-helixtrans-72.2-28.4-179.200000112.6T337 T338 V339 V343 F470T337-A341 WeakPolarHBondContact O-CB 3.21Å; T337-A341 PolarHBondContact O-N 3.46Å; T337-A341 VanDerWaalsContact O-N 3.15Å; T338-A341 PolarHBondContact O-N 2.9Å; V339-A341 VanDerWaalsContact C-N 3.35Å; V339-A341 PolarHBondContact O-N 2.87Å; A341-V343 PolarHBondContact O-N 3.07Å; A341-F470 HydrophobicContact CB-CD1 4.03Å; A341-F470 WeakPolarHBondContact O-CD1 3.46Å; A341-F470 VanDerWaalsContact O-CE1 3.23Å; A341-F470 WeakPolarHBondContact O-CE1 3.37Å
342S97.5Very high97Very high0 Ų012.3 Ų12.30%06%0.057CC..Hα-helixtrans-73.7-25.9-175.8-64.30000114L331 T338 V339 R340 G344 M345 Y346 R404L331-S342 WeakPolarHBondContact CD1-OG 3.44Å; L331-S342 VanDerWaalsContact CD2-OG 3.29Å; L331-S342 WeakPolarHBondContact CD2-OG 3.17Å; T338-S342 WeakPolarHBondContact O-CB 3.43Å; T338-S342 PolarHBondContact O-N 2.96Å; T338-S342 PolarHBondContact O-OG 2.76Å; V339-S342 PolarHBondContact O-N 2.9Å; V339-S342 VanDerWaalsContact O-N 3.12Å; R340-S342 VanDerWaalsContact C-N 3.34Å; S342-G344 PolarHBondContact O-N 3.08Å; S342-M345 PolarHBondContact O-N 3.33Å; S342-Y346 WeakPolarHBondContact O-CB 3.11Å; S342-Y346 PolarHBondContact O-N 3.26Å; S342-R404 WeakPolarHBondContact OG-CB 3.3Å; S342-R404 WeakPolarHBondContact OG-CD 3.35Å; S342-R404 WeakPolarHBondContact OG-CG 3.41Å
343V97.5Very high97Very high0 Ų017.6 Ų17.60%08%0.077CC..Hα-helixtrans-57.9-51.3178.2173.20000111A323 L324 V327 V339 A341 M345 Y346 L347 W481A323-V343 HydrophobicContact CB-CG1 4.46Å; L324-V343 HydrophobicContact CD2-CG2 3.77Å; V327-V343 HydrophobicContact CG1-CG2 4.38Å; V327-V343 HydrophobicContact CG2-CG2 4.29Å; V339-V343 PolarHBondContact O-N 3.48Å; A341-V343 PolarHBondContact O-N 3.07Å; V343-M345 PolarHBondContact O-N 2.69Å; V343-Y346 PolarHBondContact O-N 3.32Å; V343-L347 HydrophobicContact CG1-CD1 4.07Å; V343-L347 VanDerWaalsContact O-CG 3.3Å; V343-L347 WeakPolarHBondContact O-CG 3.11Å; V343-L347 PolarHBondContact O-N 3.2Å; V343-W481 HydrophobicContact CB-CZ2 4.19Å; V343-W481 HydrophobicContact CG1-CH2 4.48Å; V343-W481 HydrophobicContact CG1-CZ2 3.93Å; V343-W481 HydrophobicContact CG2-CZ2 4.12Å
344G96.5Very high97Very high0 Ų025 Ų250%011%0.109CC..Hα-helixtrans-61.6-45.1176.200000112.2I288 S342 Y346 L347 V348I288-G344 WeakPolarHBondContact CD1-O 3.19Å; S342-G344 PolarHBondContact O-N 3.08Å; G344-Y346 VanDerWaalsContact C-N 3.33Å; G344-Y346 PolarHBondContact O-N 3.35Å; G344-L347 PolarHBondContact O-N 2.76Å; G344-V348 WeakPolarHBondContact O-CG1 3.32Å; G344-V348 PolarHBondContact O-N 3.35Å
345M98.4Very high97Very high3 Ų331.4 Ų31.42%0.01514%0.137CC..Hα-helixtrans-67-33.1-177.6-159.3174.2-170.700113.2L256 S342 V343 V348 S349 R404 A405 T408 T409 L416 F470L256-M345 HydrophobicContact CD1-CE 3.56Å; L256-M345 HydrophobicContact CD1-CG 4.42Å; S342-M345 PolarHBondContact O-N 3.33Å; V343-M345 PolarHBondContact O-N 2.69Å; M345-V348 WeakPolarHBondContact O-CG1 3.36Å; M345-S349 VanDerWaalsContact O-CB 3.26Å; M345-S349 WeakPolarHBondContact O-CB 3.35Å; M345-S349 PolarHBondContact O-N 2.94Å; M345-S349 VanDerWaalsContact O-N 3.13Å; M345-S349 PolarHBondContact O-OG 3.16Å; M345-R404 HydrophobicContact SD-CG 3.86Å; M345-R404 PolarHBondContact SD-NH1 2.93Å; M345-A405 HydrophobicContact CE-CB 3.7Å; M345-A405 HydrophobicContact SD-CB 4.19Å; M345-T408 HydrophobicContact CB-CG2 4.39Å; M345-T408 VanDerWaalsContact CG-OG1 3.24Å; M345-T408 WeakPolarHBondContact CG-OG1 3.47Å; M345-T408 PolarHBondContact SD-OG1 3Å; M345-T408 VanDerWaalsContact SD-OG1 3.38Å; M345-T409 HydrophobicContact CE-CG2 4.04Å; M345-L416 HydrophobicContact CE-CD1 4.39Å; M345-F470 HydrophobicContact CB-CE1 4.4Å
346Y98.8Very high97.1Very high17 Ų1732.5 Ų32.57%0.06714%0.143CC..Hα-helixtrans-67.2-49.8173.4-176.3-93.4000110.9E326 V327 S342 V343 G344 V348 S349 K350 A411 H412E326-Y346 HydrophobicContact CB-CE1 4.42Å; E326-Y346 PolarHBondContact OE2-OH 3.33Å; V327-Y346 HydrophobicContact CG2-CD1 3.94Å; V327-Y346 HydrophobicContact CG2-CD2 4.2Å; V327-Y346 HydrophobicContact CG2-CG 3.72Å; S342-Y346 WeakPolarHBondContact O-CB 3.11Å; S342-Y346 PolarHBondContact O-N 3.26Å; V343-Y346 PolarHBondContact O-N 3.32Å; G344-Y346 VanDerWaalsContact C-N 3.33Å; G344-Y346 PolarHBondContact O-N 3.35Å; Y346-V348 PolarHBondContact O-N 3.15Å; Y346-S349 WeakPolarHBondContact O-CB 3.47Å; Y346-S349 PolarHBondContact O-N 3.12Å; Y346-K350 PolarHBondContact O-N 3.36Å; Y346-A411 HydrophobicContact CD2-CB 3.97Å; Y346-A411 HydrophobicContact CE2-CB 3.57Å; Y346-H412 AromaticContact CD1-NE2 3.76Å; Y346-H412 AromaticContact CD2-NE2 3.58Å; Y346-H412 AromaticContact CE1-CE1 3.96Å; Y346-H412 AromaticContact CE1-NE2 3.57Å; Y346-H412 AromaticContact CE2-CE1 3.92Å; Y346-H412 AromaticContact CE2-NE2 3.36Å; Y346-H412 WeakPolarHBondContact CE2-NE2 3.45Å; Y346-H412 AromaticContact CG-NE2 3.77Å; Y346-H412 AromaticContact CZ-CE1 3.59Å; Y346-H412 AromaticContact CZ-NE2 3.35Å; Y346-H412 VanDerWaalsContact CZ-NE2 3.35Å; Y346-H412 PolarHBondContact O-CD2 2.73Å; Y346-H412 PolarHBondContact O-NE2 2.83Å
347L98.7Very high97.3Very high9 Ų936.4 Ų36.45%0.04716%0.164CC..Hα-helixtrans-64-40.6-179.3-68.3175.9000112.7I288 F315 E319 A323 V343 G344 S349 K350 Y351I288-L347 HydrophobicContact CD1-CB 3.61Å; F315-L347 HydrophobicContact CB-CD1 3.89Å; F315-L347 HydrophobicContact CD2-CD1 3.94Å; F315-L347 HydrophobicContact CG-CD1 4.03Å; E319-L347 HydrophobicContact CG-CD1 4.03Å; E319-L347 HydrophobicContact CG-CD2 3.95Å; A323-L347 HydrophobicContact CB-CD2 4.24Å; V343-L347 HydrophobicContact CG1-CD1 4.07Å; V343-L347 VanDerWaalsContact O-CG 3.3Å; V343-L347 WeakPolarHBondContact O-CG 3.11Å; V343-L347 PolarHBondContact O-N 3.2Å; G344-L347 PolarHBondContact O-N 2.76Å; L347-S349 VanDerWaalsContact C-N 3.35Å; L347-K350 WeakPolarHBondContact O-CB 3.21Å; L347-K350 PolarHBondContact O-N 3.1Å; L347-Y351 PolarHBondContact O-N 3.19Å
348V98.7Very high97.6Very high3 Ų335 Ų352%0.01816%0.156CC..Hα-helixtrans-67.1-37.7175.374.30000111.4L256 F286 I288 V313 G344 M345 Y346 K350 Y351 I352L256-V348 HydrophobicContact CD2-CG1 4.03Å; L256-V348 HydrophobicContact CD2-CG2 4.38Å; F286-V348 HydrophobicContact CB-CG2 3.86Å; I288-V348 HydrophobicContact CB-CB 3.88Å; I288-V348 HydrophobicContact CB-CG2 4.14Å; I288-V348 HydrophobicContact CD1-CB 4.02Å; I288-V348 HydrophobicContact CG2-CB 3.85Å; I288-V348 HydrophobicContact CG2-CG1 4.16Å; I288-V348 HydrophobicContact CG2-CG2 4.36Å; V313-V348 HydrophobicContact CG2-CG2 4.07Å; G344-V348 WeakPolarHBondContact O-CG1 3.32Å; G344-V348 PolarHBondContact O-N 3.35Å; M345-V348 WeakPolarHBondContact O-CG1 3.36Å; Y346-V348 PolarHBondContact O-N 3.15Å; V348-K350 PolarHBondContact O-N 3.03Å; V348-Y351 WeakPolarHBondContact O-CB 3.2Å; V348-Y351 PolarHBondContact O-N 2.76Å; V348-I352 HydrophobicContact CG2-CD1 4.24Å; V348-I352 VanDerWaalsContact O-CG1 3.23Å; V348-I352 WeakPolarHBondContact O-CG1 3.43Å; V348-I352 PolarHBondContact O-N 3Å
349S98.8Very high97.7Very high1 Ų135.3 Ų35.31%0.00716%0.158CC..Hα-helixtrans-64.1-41.1175.4-64.40000111.5M345 Y346 L347 Y351 I352 R353 T408 L414M345-S349 VanDerWaalsContact O-CB 3.26Å; M345-S349 WeakPolarHBondContact O-CB 3.35Å; M345-S349 PolarHBondContact O-N 2.94Å; M345-S349 VanDerWaalsContact O-N 3.13Å; M345-S349 PolarHBondContact O-OG 3.16Å; Y346-S349 WeakPolarHBondContact O-CB 3.47Å; Y346-S349 PolarHBondContact O-N 3.12Å; L347-S349 VanDerWaalsContact C-N 3.35Å; S349-Y351 VanDerWaalsContact C-N 3.33Å; S349-Y351 PolarHBondContact O-N 2.99Å; S349-I352 PolarHBondContact O-N 3.2Å; S349-R353 PolarHBondContact O-N 2.96Å; S349-R353 VanDerWaalsContact O-N 3.09Å; S349-T408 WeakPolarHBondContact CB-O 3.42Å; S349-T408 PolarHBondContact OG-O 3.45Å; S349-L414 WeakPolarHBondContact O-CD1 3.37Å
350K98.8Very high97.8Very high91 Ų9135.3 Ų35.340%0.39616%0.158SC..Hα-helixtrans-59.4-43.5172.3-170.6175.7-178.6172.40111.5Y346 L347 V348 K354 H412Y346-K350 PolarHBondContact O-N 3.36Å; L347-K350 WeakPolarHBondContact O-CB 3.21Å; L347-K350 PolarHBondContact O-N 3.1Å; V348-K350 PolarHBondContact O-N 3.03Å; K350-K354 VanDerWaalsContact O-CB 3.25Å; K350-K354 WeakPolarHBondContact O-CB 3.45Å; K350-K354 PolarHBondContact O-N 3.35Å; K350-K354 VanDerWaalsContact O-N 3.12Å; K350-H412 PolarHBondContact N-CD2 3.49Å
351Y98.8Very high98.1Very high70 Ų7035.1 Ų35.128%0.27516%0.157SC..Hα-helixtrans-61.6-52.9175.9-179.9-81.1000111.5F286 H311 V313 L347 V348 S349 R353 K354 K355F286-Y351 HydrophobicContact CD1-CD1 4.5Å; H311-Y351 HydrophobicContact CB-CE1 4.22Å; H311-Y351 AromaticContact ND1-CE1 3.87Å; V313-Y351 HydrophobicContact CG1-CD2 3.96Å; V313-Y351 HydrophobicContact CG1-CG 4.11Å; V313-Y351 HydrophobicContact CG2-CD1 3.61Å; V313-Y351 HydrophobicContact CG2-CD2 3.86Å; V313-Y351 HydrophobicContact CG2-CE1 3.99Å; V313-Y351 HydrophobicContact CG2-CE2 4.17Å; V313-Y351 HydrophobicContact CG2-CG 3.56Å; L347-Y351 PolarHBondContact O-N 3.19Å; V348-Y351 WeakPolarHBondContact O-CB 3.2Å; V348-Y351 PolarHBondContact O-N 2.76Å; S349-Y351 VanDerWaalsContact C-N 3.33Å; S349-Y351 PolarHBondContact O-N 2.99Å; Y351-R353 VanDerWaalsContact C-N 3.32Å; Y351-R353 PolarHBondContact O-N 3.25Å; Y351-K354 PolarHBondContact O-N 3.22Å; Y351-K355 HydrophobicContact CD1-CB 4.15Å; Y351-K355 HydrophobicContact CD1-CG 4.3Å; Y351-K355 HydrophobicContact CD2-CG 3.95Å; Y351-K355 HydrophobicContact CE1-CB 3.81Å; Y351-K355 HydrophobicContact CE1-CG 4.13Å; Y351-K355 HydrophobicContact CE2-CB 4.38Å; Y351-K355 HydrophobicContact CE2-CG 3.81Å; Y351-K355 HydrophobicContact CG-CG 4.2Å; Y351-K355 VanDerWaalsContact O-CB 3.31Å; Y351-K355 WeakPolarHBondContact O-CB 3.44Å; Y351-K355 WeakPolarHBondContact O-CG 3.3Å; Y351-K355 PolarHBondContact O-N 3.4Å
352I98.8Very high98.4Very high0 Ų034.8 Ų34.80%015%0.154CC..Hα-helixtrans-52.9-51.7-178.2-70.3163.1000110L256 F286 V348 S349 K354 K355 T356 S358 I361 L414L256-I352 HydrophobicContact CD2-CD1 3.92Å; F286-I352 HydrophobicContact CB-CD1 4.11Å; F286-I352 HydrophobicContact CB-CG1 4.3Å; F286-I352 HydrophobicContact CD1-CD1 4.23Å; F286-I352 HydrophobicContact CD1-CG1 3.54Å; F286-I352 HydrophobicContact CD2-CD1 3.73Å; F286-I352 HydrophobicContact CD2-CG1 3.81Å; F286-I352 HydrophobicContact CE1-CG1 3.71Å; F286-I352 HydrophobicContact CE2-CD1 4.19Å; F286-I352 HydrophobicContact CE2-CG1 3.95Å; F286-I352 HydrophobicContact CE2-CG2 4.42Å; F286-I352 HydrophobicContact CG-CD1 3.75Å; F286-I352 HydrophobicContact CG-CG1 3.6Å; F286-I352 HydrophobicContact CZ-CG1 3.9Å; F286-I352 HydrophobicContact CZ-CG2 4.27Å; V348-I352 HydrophobicContact CG2-CD1 4.24Å; V348-I352 VanDerWaalsContact O-CG1 3.23Å; V348-I352 WeakPolarHBondContact O-CG1 3.43Å; V348-I352 PolarHBondContact O-N 3Å; S349-I352 PolarHBondContact O-N 3.2Å; I352-K354 VanDerWaalsContact C-N 3.32Å; I352-K354 PolarHBondContact O-N 3.46Å; I352-K355 PolarHBondContact O-N 2.86Å; I352-T356 PolarHBondContact O-N 3.05Å; I352-T356 PolarHBondContact O-OG1 3.16Å; I352-S358 WeakPolarHBondContact CG2-O 3.39Å; I352-I361 HydrophobicContact CD1-CD1 4.26Å; I352-I361 HydrophobicContact CD1-CG1 4.48Å; I352-I361 HydrophobicContact CG2-CD1 3.87Å; I352-I361 HydrophobicContact CG2-CG1 4.49Å; I352-L414 HydrophobicContact CB-CD1 3.81Å; I352-L414 HydrophobicContact CD1-CD1 4.28Å; I352-L414 HydrophobicContact CG2-CD1 3.69Å; I352-L414 HydrophobicContact CG2-CD2 3.9Å; I352-L414 HydrophobicContact CG2-CG 4.48Å
353R98.3Very high98.5Very high115 Ų11535.1 Ų35.143%0.43416%0.157SC..Hα-helixtrans-61.9-37.5179.4174.858.6-176.5-79.32.8113.2S349 Y351 H412 L414S349-R353 PolarHBondContact O-N 2.96Å; S349-R353 VanDerWaalsContact O-N 3.09Å; Y351-R353 VanDerWaalsContact C-N 3.32Å; Y351-R353 PolarHBondContact O-N 3.25Å; R353-H412 HydrophobicContact CB-CB 4.02Å; R353-H412 WeakPolarHBondContact CB-O 3.41Å; R353-H412 WeakPolarHBondContact CD-O 3.28Å; R353-H412 HydrophobicContact CG-CB 4.48Å; R353-H412 VanDerWaalsContact CG-O 3.24Å; R353-H412 WeakPolarHBondContact CG-O 3.39Å; R353-H412 PolarHBondContact NH1-O 2.88Å; R353-L414 HydrophobicContact CB-CD2 4.35Å
354K98.4Very high98.5Very high161 Ų16135.6 Ų35.670%0.716%0.162SC*.Hα-helixtrans-81.1-28.9-175.3-175.1173.4-1781780112.9K350 Y351 I352K350-K354 VanDerWaalsContact O-CB 3.25Å; K350-K354 WeakPolarHBondContact O-CB 3.45Å; K350-K354 PolarHBondContact O-N 3.35Å; K350-K354 VanDerWaalsContact O-N 3.12Å; Y351-K354 PolarHBondContact O-N 3.22Å; I352-K354 VanDerWaalsContact C-N 3.32Å; I352-K354 PolarHBondContact O-N 3.46Å
355K98.5Very high98.6Very high134 Ų13436.7 Ų36.758%0.58317%0.167SC*.Hα-helixtrans-116.5-14.6-165.9-62-61.5-170.7170.60114.1Y351 I352Y351-K355 HydrophobicContact CD1-CB 4.15Å; Y351-K355 HydrophobicContact CD1-CG 4.3Å; Y351-K355 HydrophobicContact CD2-CG 3.95Å; Y351-K355 HydrophobicContact CE1-CB 3.81Å; Y351-K355 HydrophobicContact CE1-CG 4.13Å; Y351-K355 HydrophobicContact CE2-CB 4.38Å; Y351-K355 HydrophobicContact CE2-CG 3.81Å; Y351-K355 HydrophobicContact CG-CG 4.2Å; Y351-K355 VanDerWaalsContact O-CB 3.31Å; Y351-K355 WeakPolarHBondContact O-CB 3.44Å; Y351-K355 WeakPolarHBondContact O-CG 3.3Å; Y351-K355 PolarHBondContact O-N 3.4Å; I352-K355 PolarHBondContact O-N 2.86Å
356T98.5Very high98.5Very high23 Ų2336.6 Ų36.614%0.14117%0.166CC..  trans-136.2172.3-177.475.70000111.5F286 I352 S358F286-T356 HydrophobicContact CE1-CG2 3.71Å; F286-T356 HydrophobicContact CZ-CG2 3.9Å; I352-T356 PolarHBondContact O-N 3.05Å; I352-T356 PolarHBondContact O-OG1 3.16Å; T356-S358 PolarHBondContact OG1-N 3.36Å
357D97.4Very high98.5Very high91 Ų9135.8 Ų35.849%0.48716%0.163SC..  trans-102.15.1171.363.5-31.8000112.7R252 V359R252-D357 WeakPolarHBondContact CB-O 3.31Å; R252-D357 VanDerWaalsContact CD-CG 3.41Å; R252-D357 WeakPolarHBondContact CD-OD1 3.3Å; R252-D357 WeakPolarHBondContact CD-OD2 3.33Å; R252-D357 IonicContact CZ-OD1 3.45Å; R252-D357 IonicContact NE-OD1 2.82Å; R252-D357 IonicContact NH1-OD1 2.81Å; R252-D357 PolarHBondContact NH1-OD1 2.99Å; R252-D357 IonicContact NH1-OD2 3.14Å; D357-V359 WeakPolarHBondContact O-CG2 3.42Å; D357-V359 PolarHBondContact O-N 3.27Å
358S98.6Very high98.5Very high1 Ų136.1 Ų36.11%0.00717%0.165CC..EExtended strand (participates in β ladder)trans-64.7124.3171.2-76.20000110.4Q284 I352 T356 L414Q284-S358 PolarHBondContact OE1-OG 2.78Å; I352-S358 WeakPolarHBondContact CG2-O 3.39Å; T356-S358 PolarHBondContact OG1-N 3.36Å; S358-L414 WeakPolarHBondContact O-CD2 3.12Å
359V98.8Very high98.5Very high10 Ų1036.2 Ų36.26%0.06117%0.165CC..EExtended strand (participates in β ladder)trans-123.1-41-173171.10000110.8L50 R251 R252 D357 E415L50-V359 HydrophobicContact CD1-CG1 3.87Å; L50-V359 HydrophobicContact CD2-CG1 3.79Å; L50-V359 HydrophobicContact CG-CG1 4.1Å; R251-V359 HydrophobicContact CB-CB 4.03Å; R251-V359 HydrophobicContact CB-CG1 4.29Å; R251-V359 HydrophobicContact CG-CG1 4.41Å; R252-V359 PolarHBondContact O-N 3.34Å; D357-V359 WeakPolarHBondContact O-CG2 3.42Å; D357-V359 PolarHBondContact O-N 3.27Å; V359-E415 PolarHBondContact O-N 2.79Å
360V98.8Very high98.5Very high0 Ų036.1 Ų36.10%017%0.165CC..EExtended strand (participates in β ladder)trans-90.3114.4174.1176.20000108.2V52 T249 R251 R252 I253 G254 F362 E415 R417V52-V360 HydrophobicContact CG1-CG2 3.66Å; T249-V360 HydrophobicContact CG2-CG2 4.2Å; R251-V360 HydrophobicContact CB-CG2 4.49Å; R252-V360 PolarHBondContact O-N 3.37Å; R252-V360 VanDerWaalsContact O-N 3.15Å; I253-V360 CarbonylContact C-O 3.58Å; I253-V360 WeakPolarHBondContact CA-O 3.4Å; I253-V360 HydrophobicContact CG1-CB 4.22Å; I253-V360 HydrophobicContact CG1-CG1 4.31Å; G254-V360 PolarHBondContact N-O 3.44Å; V360-F362 HydrophobicContact CG1-CD2 4.33Å; V360-F362 HydrophobicContact CG1-CE2 4.04Å; V360-E415 CarbonylContact C-O 2.77Å; V360-R417 VanDerWaalsContact CG1-CD 3.45Å; V360-R417 HydrophobicContact CG1-CG 3.91Å
361I98.9Very high98.4Very high1 Ų131.8 Ų31.81%0.00515%0.146CC..EExtended strand (participates in β ladder)trans-114.6115.5-173.3-53.5-56.7000109.6G254 L256 F286 I352 L414 E415 L416 R417G254-I361 WeakPolarHBondContact O-CA 3.22Å; L256-I361 HydrophobicContact CD1-CG2 4.37Å; L256-I361 HydrophobicContact CD2-CG2 3.9Å; L256-I361 HydrophobicContact CG-CG2 3.64Å; F286-I361 HydrophobicContact CE2-CD1 4.4Å; I352-I361 HydrophobicContact CD1-CD1 4.26Å; I352-I361 HydrophobicContact CD1-CG1 4.48Å; I352-I361 HydrophobicContact CG2-CD1 3.87Å; I352-I361 HydrophobicContact CG2-CG1 4.49Å; I361-L414 HydrophobicContact CG1-CB 4.19Å; I361-L414 HydrophobicContact CG1-CD1 4.17Å; I361-E415 PolarHBondContact N-O 2.89Å; I361-L416 WeakPolarHBondContact O-CA 3.5Å; I361-R417 PolarHBondContact O-N 2.93Å
362F98.9Very high98.4Very high0 Ų028.5 Ų28.50%013%0.133CC..EExtended strand (participates in β ladder)trans-79.6146.3172.6-80.4-112000111V243 R246 I253 G254 C255 L256 V266 L270 V360 R417 P419V243-F362 HydrophobicContact CG1-CE1 3.97Å; R246-F362 HydrophobicContact CB-CE1 3.65Å; R246-F362 HydrophobicContact CB-CZ 3.6Å; R246-F362 WeakPolarHBondContact O-CZ 3.47Å; I253-F362 HydrophobicContact CD1-CE2 4.37Å; I253-F362 HydrophobicContact CG1-CE2 4.5Å; I253-F362 HydrophobicContact CG2-CD2 3.53Å; I253-F362 HydrophobicContact CG2-CE2 3.49Å; I253-F362 VanDerWaalsContact CG2-CE2 3.49Å; G254-F362 PolarHBondContact O-N 2.88Å; C255-F362 WeakPolarHBondContact CA-O 3.11Å; C255-F362 HydrophobicContact CB-CB 4.26Å; L256-F362 PolarHBondContact N-O 2.86Å; V266-F362 HydrophobicContact CG1-CB 3.79Å; V266-F362 HydrophobicContact CG1-CD1 4.08Å; V266-F362 HydrophobicContact CG1-CG 4.42Å; L270-F362 HydrophobicContact CD1-CD1 4.36Å; L270-F362 HydrophobicContact CD1-CD2 4.26Å; L270-F362 HydrophobicContact CD1-CE1 4.05Å; L270-F362 HydrophobicContact CD1-CE2 3.96Å; L270-F362 HydrophobicContact CD1-CG 4.43Å; L270-F362 HydrophobicContact CD1-CZ 3.81Å; L270-F362 HydrophobicContact CD2-CB 3.95Å; L270-F362 HydrophobicContact CD2-CD1 4.3Å; L270-F362 HydrophobicContact CD2-CD2 3.86Å; L270-F362 HydrophobicContact CD2-CE2 4.38Å; L270-F362 HydrophobicContact CD2-CG 3.79Å; V360-F362 HydrophobicContact CG1-CD2 4.33Å; V360-F362 HydrophobicContact CG1-CE2 4.04Å; F362-R417 WeakPolarHBondContact CA-O 3.37Å; F362-R417 HydrophobicContact CD1-CB 4.3Å; F362-R417 HydrophobicContact CD2-CB 4.28Å; F362-R417 HydrophobicContact CE1-CB 4.36Å; F362-R417 HydrophobicContact CE2-CB 4.34Å; F362-R417 HydrophobicContact CG-CB 4.29Å; F362-R417 HydrophobicContact CZ-CB 4.41Å; F362-P419 HydrophobicContact CD1-CG 4.45Å
363S98.7Very high98.3Very high7 Ų728.5 Ų28.55%0.04913%0.133CC..  trans-150.3166.9177.4-1630000112.4E365 R417 P419S363-E365 WeakPolarHBondContact CB-OE2 3.32Å; S363-E365 PolarHBondContact OG-OE2 2.81Å; S363-R417 PolarHBondContact N-O 3.47Å; S363-P419 WeakPolarHBondContact O-CD 3.43Å
364G98.2Very high98.1Very high10 Ų1024.4 Ų24.410%0.10312%0.118CC..  trans-94.73-17200000116.3S367G364-S367 PolarHBondContact O-N 3.06Å
365E98.1Very high97.7Very high24 Ų2418.6 Ų18.611%0.1129%0.094CC..THydrogen-bonded Turntrans-56.8146.9-179.2-7776.3-171.100112.8S363 S367 D401 R404 A405 V418S363-E365 WeakPolarHBondContact CB-OE2 3.32Å; S363-E365 PolarHBondContact OG-OE2 2.81Å; E365-S367 VanDerWaalsContact C-N 3.35Å; E365-D401 HydrophobicContact CG-CB 4.4Å; E365-R404 IonicContact OE1-CZ 3.1Å; E365-R404 IonicContact OE1-NH1 2.55Å; E365-R404 PolarHBondContact OE1-NH1 3.39Å; E365-R404 IonicContact OE1-NH2 3.43Å; E365-R404 PolarHBondContact OE1-NH2 3.42Å; E365-A405 HydrophobicContact CG-CB 4.06Å; E365-V418 HydrophobicContact CB-CG1 3.97Å
366G98.1Very high97.4Very high0 Ų012.4 Ų12.40%07%0.067CC..THydrogen-bonded Turntrans93.8-18.5-175.500000114E369 L370G366-E369 VanDerWaalsContact C-OE2 3.32Å; G366-E369 WeakPolarHBondContact CA-OE2 3.36Å; G366-E369 PolarHBondContact N-OE2 3.44Å; G366-L370 WeakPolarHBondContact O-CB 3.34Å; G366-L370 PolarHBondContact O-N 3.03Å; G366-L370 VanDerWaalsContact O-N 3.07Å
367S98.6Very high97.3Very high0 Ų011.6 Ų11.60%06%0.061CC..Hα-helixtrans-65.4-48.4-180-175.70000112D262 G364 E365 E369 L370 T371 F420D262-S367 VanDerWaalsContact CG-OG 3.28Å; D262-S367 WeakPolarHBondContact OD1-CB 3.48Å; D262-S367 PolarHBondContact OD1-OG 3.48Å; G364-S367 PolarHBondContact O-N 3.06Å; E365-S367 VanDerWaalsContact C-N 3.35Å; S367-E369 VanDerWaalsContact C-N 3.33Å; S367-E369 PolarHBondContact O-N 3.07Å; S367-L370 PolarHBondContact O-N 3.39Å; S367-T371 WeakPolarHBondContact O-CB 3.33Å; S367-T371 WeakPolarHBondContact O-CG2 3.45Å; S367-T371 PolarHBondContact O-N 2.84Å; S367-T371 PolarHBondContact O-OG1 2.87Å; S367-F420 WeakPolarHBondContact OG-CE1 3.44Å
368D97.9Very high97.1Very high17 Ų1710.8 Ų10.89%0.0916%0.055CC..Hα-helixtrans-61.5-42.6-177.8-78.1-57.6000111.9Q372 G373 Y374 K445 K467D368-Q372 WeakPolarHBondContact O-CA 3.21Å; D368-Q372 PolarHBondContact O-N 3.42Å; D368-Q372 VanDerWaalsContact O-N 3.07Å; D368-G373 PolarHBondContact O-N 3.43Å; D368-G373 WeakPolarHBondContact OD1-CA 3.21Å; D368-Y374 HydrophobicContact CB-CD1 4.24Å; D368-Y374 HydrophobicContact CB-CD2 4.14Å; D368-Y374 HydrophobicContact CB-CE1 3.89Å; D368-Y374 HydrophobicContact CB-CE2 3.77Å; D368-Y374 HydrophobicContact CB-CG 4.35Å; D368-K445 VanDerWaalsContact CG-NZ 3.28Å; D368-K445 WeakPolarHBondContact OD1-CE 3.21Å; D368-K445 IonicContact OD1-NZ 3.69Å; D368-K445 PolarHBondContact OD1-NZ 3.12Å; D368-K445 IonicContact OD2-NZ 3.39Å; D368-K467 WeakPolarHBondContact OD1-CE 3.41Å; D368-K467 WeakPolarHBondContact OD2-CE 3.26Å; D368-K467 IonicContact OD2-NZ 2.84Å
369E98.1Very high96.9Very high4 Ų414.3 Ų14.32%0.0197%0.07CC..Hα-helixtrans-66.3-43.6179.3-63.775.7-161.800111.7G366 S367 Y374 S390 L393 L394 L397G366-E369 VanDerWaalsContact C-OE2 3.32Å; G366-E369 WeakPolarHBondContact CA-OE2 3.36Å; G366-E369 PolarHBondContact N-OE2 3.44Å; S367-E369 VanDerWaalsContact C-N 3.33Å; S367-E369 PolarHBondContact O-N 3.07Å; E369-Y374 HydrophobicContact CG-CE2 4.18Å; E369-Y374 WeakPolarHBondContact OE1-CE2 3.3Å; E369-Y374 PolarHBondContact OE1-OH 2.84Å; E369-S390 WeakPolarHBondContact O-CA 3.33Å; E369-S390 VanDerWaalsContact O-CB 3.26Å; E369-S390 WeakPolarHBondContact O-CB 3.48Å; E369-S390 PolarHBondContact O-OG 2.55Å; E369-L393 HydrophobicContact CB-CB 3.85Å; E369-L393 HydrophobicContact CB-CD1 4.41Å; E369-L393 HydrophobicContact CG-CB 3.64Å; E369-L393 HydrophobicContact CG-CD1 4.23Å; E369-L393 HydrophobicContact CG-CG 4.48Å; E369-L394 HydrophobicContact CB-CD2 3.87Å; E369-L394 HydrophobicContact CB-CG 4.17Å; E369-L397 HydrophobicContact CB-CD2 4.5Å; E369-L397 VanDerWaalsContact CD-CD2 3.5Å; E369-L397 HydrophobicContact CG-CD2 3.65Å; E369-L397 HydrophobicContact CG-CG 4.13Å
370L98.4Very high96.8Very high0 Ų015 Ų150%08%0.077CC..Hα-helixtrans-71.5-41.3-179.8-177.567.2000112.6G366 S367 S390 L394 F425 T426 Y429 L430G366-L370 WeakPolarHBondContact O-CB 3.34Å; G366-L370 PolarHBondContact O-N 3.03Å; G366-L370 VanDerWaalsContact O-N 3.07Å; S367-L370 PolarHBondContact O-N 3.39Å; L370-S390 PolarHBondContact O-OG 3.36Å; L370-L394 HydrophobicContact CB-CD2 4.49Å; L370-L394 HydrophobicContact CD1-CD1 4.11Å; L370-F425 HydrophobicContact CD2-CD1 3.73Å; L370-F425 HydrophobicContact CD2-CE1 3.43Å; L370-F425 VanDerWaalsContact CD2-CE1 3.43Å; L370-F425 HydrophobicContact CD2-CZ 4.44Å; L370-T426 HydrophobicContact CD1-CG2 4.08Å; L370-T426 HydrophobicContact CD2-CG2 4.02Å; L370-Y429 HydrophobicContact CD1-CD1 4.28Å; L370-Y429 HydrophobicContact CD1-CG 4.48Å; L370-Y429 HydrophobicContact CD2-CG 4.21Å; L370-Y429 HydrophobicContact CG-CD1 3.96Å; L370-Y429 HydrophobicContact CG-CG 4.1Å; L370-L430 HydrophobicContact CD1-CD1 4.3Å; L370-L430 HydrophobicContact CD1-CD2 3.95Å; L370-L430 HydrophobicContact CD1-CG 3.75Å
371T98.3Very high96.7Very high0 Ų019 Ų190%010%0.103CC..Hα-helixtrans-105.613.6-167.568.70000113.9S367 G373 Y429 K445 L448S367-T371 WeakPolarHBondContact O-CB 3.33Å; S367-T371 WeakPolarHBondContact O-CG2 3.45Å; S367-T371 PolarHBondContact O-N 2.84Å; S367-T371 PolarHBondContact O-OG1 2.87Å; T371-G373 VanDerWaalsContact C-N 3.31Å; T371-G373 PolarHBondContact O-N 3.04Å; T371-Y429 HydrophobicContact CG2-CD1 4.47Å; T371-Y429 HydrophobicContact CG2-CD2 4.42Å; T371-Y429 HydrophobicContact CG2-CE1 3.89Å; T371-Y429 HydrophobicContact CG2-CE2 3.83Å; T371-K445 WeakPolarHBondContact OG1-CD 3.08Å; T371-K445 VanDerWaalsContact OG1-CG 3.28Å; T371-K445 WeakPolarHBondContact OG1-CG 3.31Å; T371-L448 HydrophobicContact CG2-CD2 4.35Å
372Q97.7Very high96.7Very high0 Ų020.3 Ų20.30%011%0.112CC..THydrogen-bonded Turntrans58.144.8177.2-58.6175.32.300111.9D368 F377 A386 R437D368-Q372 WeakPolarHBondContact O-CA 3.21Å; D368-Q372 PolarHBondContact O-N 3.42Å; D368-Q372 VanDerWaalsContact O-N 3.07Å; Q372-F377 VanDerWaalsContact C-CD2 3.43Å; Q372-F377 HydrophobicContact CB-CB 4.15Å; Q372-F377 HydrophobicContact CB-CD1 3.61Å; Q372-F377 HydrophobicContact CB-CD2 4Å; Q372-F377 HydrophobicContact CB-CE1 3.9Å; Q372-F377 HydrophobicContact CB-CE2 4.26Å; Q372-F377 HydrophobicContact CB-CG 3.66Å; Q372-F377 HydrophobicContact CB-CZ 4.21Å; Q372-F377 HydrophobicContact CG-CD1 3.81Å; Q372-F377 HydrophobicContact CG-CE1 3.68Å; Q372-F377 HydrophobicContact CG-CG 4.36Å; Q372-F377 HydrophobicContact CG-CZ 4.13Å; Q372-F377 WeakPolarHBondContact O-CB 3.34Å; Q372-A386 VanDerWaalsContact NE2-C 3.29Å; Q372-A386 PolarHBondContact NE2-O 2.92Å; Q372-R437 PolarHBondContact OE1-O 2.83Å
373G96.3Very high96.6Very high0 Ų021.8 Ų21.80%012%0.121CC..  trans-85.9-15.7-16900000116.1D368 T371 E444 K445D368-G373 PolarHBondContact O-N 3.43Å; D368-G373 WeakPolarHBondContact OD1-CA 3.21Å; T371-G373 VanDerWaalsContact C-N 3.31Å; T371-G373 PolarHBondContact O-N 3.04Å; G373-E444 WeakPolarHBondContact O-CG 3.28Å; G373-K445 VanDerWaalsContact CA-CE 3.4Å
374Y94.1Very high96.6Very high30 Ų3026 Ų2612%0.11814%0.141CC..SBendtrans-70.9141175.5-66-59.8000111.4D368 E369 Y376 F377 L393 W537D368-Y374 HydrophobicContact CB-CD1 4.24Å; D368-Y374 HydrophobicContact CB-CD2 4.14Å; D368-Y374 HydrophobicContact CB-CE1 3.89Å; D368-Y374 HydrophobicContact CB-CE2 3.77Å; D368-Y374 HydrophobicContact CB-CG 4.35Å; E369-Y374 HydrophobicContact CG-CE2 4.18Å; E369-Y374 WeakPolarHBondContact OE1-CE2 3.3Å; E369-Y374 PolarHBondContact OE1-OH 2.84Å; Y374-Y376 AromaticContact CD2-CE1 3.96Å; Y374-Y376 HydrophobicContact CD2-CE1 3.96Å; Y374-Y376 HydrophobicContact CG-CD1 4.42Å; Y374-Y376 AromaticContact CG-CE1 3.86Å; Y374-Y376 HydrophobicContact CG-CE1 3.86Å; Y374-Y376 PolarHBondContact O-N 3.2Å; Y374-F377 HydrophobicContact CD2-CE2 4.11Å; Y374-F377 WeakPolarHBondContact O-CB 3.29Å; Y374-F377 WeakPolarHBondContact O-CD2 3.45Å; Y374-F377 PolarHBondContact O-N 3.14Å; Y374-L393 HydrophobicContact CD2-CD1 3.89Å; Y374-L393 HydrophobicContact CE2-CD1 4.03Å; Y374-W537 HydrophobicContact CD1-CZ2 4.36Å; Y374-W537 HydrophobicContact CD2-CZ2 4.23Å; Y374-W537 HydrophobicContact CE1-CZ2 4.23Å; Y374-W537 HydrophobicContact CE2-CZ2 4.12Å; Y374-W537 HydrophobicContact CG-CZ2 4.37Å
375I90.9Very high96.6Very high38 Ų3829.1 Ų29.120%0.19515%0.152CC..G310 helixtrans-55.6-29.8-175.8-61.6-58.2000113.2F377 H378 K467 Y555I375-F377 PolarHBondContact O-N 2.81Å; I375-H378 WeakPolarHBondContact O-CB 3.42Å; I375-H378 PolarHBondContact O-CD2 2.65Å; I375-H378 VanDerWaalsContact O-CD2 3.24Å; I375-H378 PolarHBondContact O-N 2.82Å; I375-K467 HydrophobicContact CD1-CB 4.1Å; I375-Y555 HydrophobicContact CG1-CE2 4.06Å
376Y92.8Very high96.6Very high5 Ų528 Ų282%0.0215%0.147CC..G310 helixtrans-69.1-15.6179.274.5-89.9000113.7Y374 H378 K379 E389 L393 W537 P539 R540 W541Y374-Y376 AromaticContact CD2-CE1 3.96Å; Y374-Y376 HydrophobicContact CD2-CE1 3.96Å; Y374-Y376 HydrophobicContact CG-CD1 4.42Å; Y374-Y376 AromaticContact CG-CE1 3.86Å; Y374-Y376 HydrophobicContact CG-CE1 3.86Å; Y374-Y376 PolarHBondContact O-N 3.2Å; Y376-H378 PolarHBondContact O-N 2.9Å; Y376-K379 WeakPolarHBondContact O-CB 3.47Å; Y376-K379 PolarHBondContact O-N 3.48Å; Y376-E389 HydrophobicContact CE2-CG 3.88Å; Y376-E389 PolarHBondContact OH-OE1 3.43Å; Y376-L393 WeakPolarHBondContact OH-CD1 3.35Å; Y376-W537 HydrophobicContact CE1-CH2 4.35Å; Y376-W537 HydrophobicContact CE1-CZ2 4.32Å; Y376-P539 HydrophobicContact CD1-CB 3.65Å; Y376-P539 HydrophobicContact CD2-CB 4.35Å; Y376-P539 HydrophobicContact CE1-CB 4.21Å; Y376-P539 HydrophobicContact CG-CB 3.73Å; Y376-R540 HydrophobicContact CD2-CB 4.16Å; Y376-R540 WeakPolarHBondContact CD2-O 3.34Å; Y376-R540 HydrophobicContact CE2-CB 3.93Å; Y376-W541 AromaticContact CD2-CE3 3.7Å; Y376-W541 HydrophobicContact CD2-CE3 3.7Å; Y376-W541 AromaticContact CD2-CZ3 3.72Å; Y376-W541 HydrophobicContact CD2-CZ3 3.72Å; Y376-W541 HydrophobicContact CE2-CE3 4.23Å; Y376-W541 AromaticContact CE2-CZ3 3.89Å; Y376-W541 HydrophobicContact CE2-CZ3 3.89Å
377F95.5Very high96.6Very high5 Ų528.3 Ų28.32%0.02215%0.15CC..G310 helixtrans-63.5-22.9171.8-79.2-77.8000113.5Q372 Y374 I375 K379 A380 A386 E389 L393 P439 W541Q372-F377 VanDerWaalsContact C-CD2 3.43Å; Q372-F377 HydrophobicContact CB-CB 4.15Å; Q372-F377 HydrophobicContact CB-CD1 3.61Å; Q372-F377 HydrophobicContact CB-CD2 4Å; Q372-F377 HydrophobicContact CB-CE1 3.9Å; Q372-F377 HydrophobicContact CB-CE2 4.26Å; Q372-F377 HydrophobicContact CB-CG 3.66Å; Q372-F377 HydrophobicContact CB-CZ 4.21Å; Q372-F377 HydrophobicContact CG-CD1 3.81Å; Q372-F377 HydrophobicContact CG-CE1 3.68Å; Q372-F377 HydrophobicContact CG-CG 4.36Å; Q372-F377 HydrophobicContact CG-CZ 4.13Å; Q372-F377 WeakPolarHBondContact O-CB 3.34Å; Y374-F377 HydrophobicContact CD2-CE2 4.11Å; Y374-F377 WeakPolarHBondContact O-CB 3.29Å; Y374-F377 WeakPolarHBondContact O-CD2 3.45Å; Y374-F377 PolarHBondContact O-N 3.14Å; I375-F377 PolarHBondContact O-N 2.81Å; F377-K379 PolarHBondContact O-N 3.03Å; F377-K379 VanDerWaalsContact O-N 3.11Å; F377-A380 WeakPolarHBondContact O-CB 3.46Å; F377-A380 PolarHBondContact O-N 3.48Å; F377-A380 VanDerWaalsContact O-N 3.09Å; F377-A386 HydrophobicContact CD1-CB 4.08Å; F377-A386 HydrophobicContact CE1-CB 4.38Å; F377-A386 WeakPolarHBondContact CE1-O 3.48Å; F377-E389 HydrophobicContact CE1-CB 3.93Å; F377-E389 HydrophobicContact CE1-CG 3.71Å; F377-E389 HydrophobicContact CZ-CB 4.27Å; F377-E389 HydrophobicContact CZ-CG 3.66Å; F377-L393 HydrophobicContact CE2-CD1 3.82Å; F377-L393 HydrophobicContact CZ-CD1 3.71Å; F377-P439 HydrophobicContact CB-CG 4.24Å; F377-W541 HydrophobicContact CD1-CH2 4.21Å; F377-W541 HydrophobicContact CD1-CZ3 4.06Å; F377-W541 HydrophobicContact CE1-CH2 4.34Å; F377-W541 HydrophobicContact CE1-CZ3 4.49Å
378H93.6Very high96.5Very high75 Ų7534 Ų3435%0.34718%0.176SC..G310 helixtrans-62.7-15170.2-68.4-70.1000113.5I375 Y376 P439 E444I375-H378 WeakPolarHBondContact O-CB 3.42Å; I375-H378 PolarHBondContact O-CD2 2.65Å; I375-H378 VanDerWaalsContact O-CD2 3.24Å; I375-H378 PolarHBondContact O-N 2.82Å; Y376-H378 PolarHBondContact O-N 2.9Å; H378-P439 VanDerWaalsContact CE1-CB 3.46Å; H378-P439 WeakPolarHBondContact CE1-CB 3.44Å; H378-P439 WeakPolarHBondContact ND1-CB 3.49Å; H378-E444 IonicContact NE2-OE2 3.93Å
379K94Very high96.5Very high74 Ų7433.2 Ų33.232%0.32217%0.172SC..G310 helixtrans-107.79177.8-61.4-175.4178.4-171.60113.3Y376 F377 P381 W541 I542 H554Y376-K379 WeakPolarHBondContact O-CB 3.47Å; Y376-K379 PolarHBondContact O-N 3.48Å; F377-K379 PolarHBondContact O-N 3.03Å; F377-K379 VanDerWaalsContact O-N 3.11Å; K379-P381 WeakPolarHBondContact O-CD 3.41Å; K379-W541 HydrophobicContact CB-CB 4.3Å; K379-I542 HydrophobicContact CD-CD1 3.84Å; K379-I542 HydrophobicContact CD-CG1 3.61Å; K379-H554 VanDerWaalsContact CE-CD2 3.49Å; K379-H554 WeakPolarHBondContact CE-CD2 3.25Å
380A96.3Very high96.5Very high25 Ų2533 Ų3321%0.20717%0.171CC..  trans-57.6128.6173.500000109.5F377 S382 A386 W541F377-A380 WeakPolarHBondContact O-CB 3.46Å; F377-A380 PolarHBondContact O-N 3.48Å; F377-A380 VanDerWaalsContact O-N 3.09Å; A380-S382 PolarHBondContact O-N 3.38Å; A380-A386 HydrophobicContact CB-CB 3.71Å; A380-W541 HydrophobicContact CB-CE3 4.08Å; A380-W541 HydrophobicContact CB-CH2 3.53Å; A380-W541 HydrophobicContact CB-CZ2 4.03Å; A380-W541 HydrophobicContact CB-CZ3 3.56Å
381P97.2Very high96.4Very high84 Ų8434.3 Ų34.355%0.54518%0.177SC..SBendtrans-67.2-26.9-178-24.135.3000113.4K379 E385 W541K379-P381 WeakPolarHBondContact O-CD 3.41Å; P381-E385 WeakPolarHBondContact CB-OE1 3.16Å; P381-E385 WeakPolarHBondContact CD-OE2 3.32Å; P381-E385 VanDerWaalsContact CG-OE2 3.24Å; P381-E385 WeakPolarHBondContact CG-OE2 3.48Å; P381-W541 VanDerWaalsContact CD-CE2 3.43Å; P381-W541 HydrophobicContact CG-CG 4.43Å
382S98.1Very high96.3Very high29 Ų2936.3 Ų36.320%0.20319%0.185CC..SBendtrans-151.5159.7178.960.60000111.5A380 E384 E385 A386A380-S382 PolarHBondContact O-N 3.38Å; S382-E384 PolarHBondContact O-N 2.93Å; S382-E385 PolarHBondContact O-N 3Å; S382-E385 WeakPolarHBondContact OG-CB 3.44Å; S382-E385 WeakPolarHBondContact OG-CG 3.45Å; S382-E385 PolarHBondContact OG-N 2.85Å; S382-E385 PolarHBondContact OG-OE1 3.07Å; S382-A386 PolarHBondContact O-N 3.12Å
383P98.3Very high96.3Very high30 Ų3036.6 Ų36.620%0.19519%0.186CC..Hα-helixtrans-56-36.9171-24.635000113.3A386 A387 A434 E435 I438P383-A386 WeakPolarHBondContact O-CB 3.41Å; P383-A386 PolarHBondContact O-N 2.8Å; P383-A387 WeakPolarHBondContact O-CB 3.3Å; P383-A387 PolarHBondContact O-N 2.58Å; P383-A434 HydrophobicContact CB-CB 3.61Å; P383-E435 HydrophobicContact CB-CG 4.27Å; P383-E435 HydrophobicContact CG-CG 4.05Å; P383-I438 HydrophobicContact CB-CG2 3.86Å; P383-I438 HydrophobicContact CG-CD1 4.31Å; P383-I438 HydrophobicContact CG-CG2 4.19Å
384E98.2Very high96.4Very high97 Ų9736.7 Ų36.745%0.45319%0.187SC..Hα-helixtrans-65.9-46.9179.2-66.567.3-147.100111.1S382 A386 A387 E388S382-E384 PolarHBondContact O-N 2.93Å; E384-A386 VanDerWaalsContact C-N 3.28Å; E384-A386 PolarHBondContact O-N 3.39Å; E384-A387 WeakPolarHBondContact O-CB 3.29Å; E384-A387 PolarHBondContact O-N 2.96Å; E384-A387 VanDerWaalsContact O-N 3.08Å; E384-E388 WeakPolarHBondContact O-CG 3.37Å; E384-E388 PolarHBondContact O-N 3.49Å
385E98.3Very high96.5Very high74 Ų7439.6 Ų39.635%0.34620%0.2SC..Hα-helixtrans-64.5-34.1175.8-75.1179.1-118.100112.2P381 S382 E389 W541P381-E385 WeakPolarHBondContact CB-OE1 3.16Å; P381-E385 WeakPolarHBondContact CD-OE2 3.32Å; P381-E385 VanDerWaalsContact CG-OE2 3.24Å; P381-E385 WeakPolarHBondContact CG-OE2 3.48Å; S382-E385 PolarHBondContact O-N 3Å; S382-E385 WeakPolarHBondContact OG-CB 3.44Å; S382-E385 WeakPolarHBondContact OG-CG 3.45Å; S382-E385 PolarHBondContact OG-N 2.85Å; S382-E385 PolarHBondContact OG-OE1 3.07Å; E385-E389 WeakPolarHBondContact O-CB 3.5Å; E385-E389 PolarHBondContact O-N 3Å; E385-W541 HydrophobicContact CB-CZ2 4.06Å; E385-W541 PolarHBondContact OE2-NE1 3.26Å
386A98.1Very high96.8Very high0 Ų039.2 Ų39.20%020%0.197CC..Hα-helixtrans-65.1-39.1171.400000112.1Q372 F377 A380 S382 P383 E384 S390 I438Q372-A386 VanDerWaalsContact NE2-C 3.29Å; Q372-A386 PolarHBondContact NE2-O 2.92Å; F377-A386 HydrophobicContact CD1-CB 4.08Å; F377-A386 HydrophobicContact CE1-CB 4.38Å; F377-A386 WeakPolarHBondContact CE1-O 3.48Å; A380-A386 HydrophobicContact CB-CB 3.71Å; S382-A386 PolarHBondContact O-N 3.12Å; P383-A386 WeakPolarHBondContact O-CB 3.41Å; P383-A386 PolarHBondContact O-N 2.8Å; E384-A386 VanDerWaalsContact C-N 3.28Å; E384-A386 PolarHBondContact O-N 3.39Å; A386-S390 WeakPolarHBondContact O-CB 3.48Å; A386-S390 PolarHBondContact O-N 3.43Å; A386-I438 HydrophobicContact CB-CG2 4.35Å
387A97.5Very high97Very high8 Ų839 Ų397%0.06620%0.197CC..Hα-helixtrans-66-45.2175.500000111.9P383 E384 E389 S390 E391 A434 R437P383-A387 WeakPolarHBondContact O-CB 3.3Å; P383-A387 PolarHBondContact O-N 2.58Å; E384-A387 WeakPolarHBondContact O-CB 3.29Å; E384-A387 PolarHBondContact O-N 2.96Å; E384-A387 VanDerWaalsContact O-N 3.08Å; A387-E389 VanDerWaalsContact C-N 3.3Å; A387-E389 PolarHBondContact O-N 2.95Å; A387-S390 WeakPolarHBondContact O-CB 3.31Å; A387-S390 PolarHBondContact O-N 3.12Å; A387-E391 WeakPolarHBondContact O-CG 3.35Å; A387-E391 PolarHBondContact O-N 3.1Å; A387-A434 HydrophobicContact CB-CB 4.32Å; A387-R437 VanDerWaalsContact CB-NH2 3.26Å
388E97.4Very high97.1Very high119 Ų11940.6 Ų40.656%0.55620%0.203SC*.Hα-helixtrans-61.4-39.3176.5-72.4-178.4-177.600112.3E384 E391 R392E384-E388 WeakPolarHBondContact O-CG 3.37Å; E384-E388 PolarHBondContact O-N 3.49Å; E388-E391 PolarHBondContact O-N 3.07Å; E388-R392 PolarHBondContact O-N 2.66Å
389E97.8Very high97.4Very high0 Ų037.4 Ų37.40%019%0.188CC..Hα-helixtrans-67.1-42.6176.3175.461.2178.700112.1Y376 F377 E385 A387 E391 R392 L393 R540 W541Y376-E389 HydrophobicContact CE2-CG 3.88Å; Y376-E389 PolarHBondContact OH-OE1 3.43Å; F377-E389 HydrophobicContact CE1-CB 3.93Å; F377-E389 HydrophobicContact CE1-CG 3.71Å; F377-E389 HydrophobicContact CZ-CB 4.27Å; F377-E389 HydrophobicContact CZ-CG 3.66Å; E385-E389 WeakPolarHBondContact O-CB 3.5Å; E385-E389 PolarHBondContact O-N 3Å; A387-E389 VanDerWaalsContact C-N 3.3Å; A387-E389 PolarHBondContact O-N 2.95Å; E389-E391 VanDerWaalsContact C-N 3.29Å; E389-E391 PolarHBondContact O-N 2.85Å; E389-R392 WeakPolarHBondContact O-CB 3.42Å; E389-R392 PolarHBondContact O-N 2.85Å; E389-R392 VanDerWaalsContact O-N 3.16Å; E389-R392 IonicContact OE1-CZ 2.74Å; E389-R392 IonicContact OE1-NE 3.83Å; E389-R392 IonicContact OE1-NH2 3.49Å; E389-R392 PolarHBondContact OE1-NH2 3.41Å; E389-R392 IonicContact OE2-CZ 3.48Å; E389-R392 IonicContact OE2-NE 3.41Å; E389-R392 PolarHBondContact OE2-NE 3.24Å; E389-R392 IonicContact OE2-NH2 3.44Å; E389-R392 PolarHBondContact OE2-NH2 2.92Å; E389-L393 HydrophobicContact CG-CD1 4.43Å; E389-L393 WeakPolarHBondContact O-CG 3.34Å; E389-L393 PolarHBondContact O-N 3.43Å; E389-R540 WeakPolarHBondContact OE2-CD 3.15Å; E389-R540 IonicContact OE2-CZ 2.71Å; E389-R540 IonicContact OE2-NE 3.71Å; E389-R540 PolarHBondContact OE2-NE 3.21Å; E389-R540 IonicContact OE2-NH1 3.58Å; E389-W541 HydrophobicContact CB-CH2 3.79Å; E389-W541 HydrophobicContact CB-CZ2 4.18Å; E389-W541 HydrophobicContact CG-CH2 4.01Å
390S97.8Very high97.6Very high0 Ų034.1 Ų34.10%017%0.174CC..Hα-helixtrans-55.8-44.9172.4172.30000111.5E369 L370 A386 A387 R392 L393 L394E369-S390 WeakPolarHBondContact O-CA 3.33Å; E369-S390 VanDerWaalsContact O-CB 3.26Å; E369-S390 WeakPolarHBondContact O-CB 3.48Å; E369-S390 PolarHBondContact O-OG 2.55Å; L370-S390 PolarHBondContact O-OG 3.36Å; A386-S390 WeakPolarHBondContact O-CB 3.48Å; A386-S390 PolarHBondContact O-N 3.43Å; A387-S390 WeakPolarHBondContact O-CB 3.31Å; A387-S390 PolarHBondContact O-N 3.12Å; S390-R392 PolarHBondContact O-N 3.25Å; S390-L393 PolarHBondContact O-N 3.41Å; S390-L394 VanDerWaalsContact O-CG 3.32Å; S390-L394 WeakPolarHBondContact O-CG 3.26Å; S390-L394 PolarHBondContact O-N 3.48Å
391E96.6Very high97.6Very high27 Ų2733.9 Ų33.913%0.12617%0.169CC..Hα-helixtrans-64.2-38.4176-71.1176.6-136.200113.3K208 A387 E388 E389 K395K208-E391 WeakPolarHBondContact CE-OE1 3.48Å; K208-E391 WeakPolarHBondContact CE-OE2 3.31Å; K208-E391 IonicContact NZ-OE1 3Å; K208-E391 PolarHBondContact NZ-OE1 2.92Å; K208-E391 IonicContact NZ-OE2 3.62Å; K208-E391 PolarHBondContact NZ-OE2 2.75Å; A387-E391 WeakPolarHBondContact O-CG 3.35Å; A387-E391 PolarHBondContact O-N 3.1Å; E388-E391 PolarHBondContact O-N 3.07Å; E389-E391 VanDerWaalsContact C-N 3.29Å; E389-E391 PolarHBondContact O-N 2.85Å; E391-K395 WeakPolarHBondContact O-CD 3.34Å; E391-K395 VanDerWaalsContact O-CG 3.25Å; E391-K395 WeakPolarHBondContact O-CG 3.49Å; E391-K395 PolarHBondContact O-N 3.48Å; E391-K395 VanDerWaalsContact O-N 3.1Å
392R96.8Very high97.7Very high43 Ų4330 Ų3016%0.16214%0.144CC..Hα-helixtrans-63.4-48.1175.5-173.8-169.170.4783.8110.6E388 E389 S390 L394 K395 E396E388-R392 PolarHBondContact O-N 2.66Å; E389-R392 WeakPolarHBondContact O-CB 3.42Å; E389-R392 PolarHBondContact O-N 2.85Å; E389-R392 VanDerWaalsContact O-N 3.16Å; E389-R392 IonicContact OE1-CZ 2.74Å; E389-R392 IonicContact OE1-NE 3.83Å; E389-R392 IonicContact OE1-NH2 3.49Å; E389-R392 PolarHBondContact OE1-NH2 3.41Å; E389-R392 IonicContact OE2-CZ 3.48Å; E389-R392 IonicContact OE2-NE 3.41Å; E389-R392 PolarHBondContact OE2-NE 3.24Å; E389-R392 IonicContact OE2-NH2 3.44Å; E389-R392 PolarHBondContact OE2-NH2 2.92Å; S390-R392 PolarHBondContact O-N 3.25Å; R392-L394 PolarHBondContact O-N 2.62Å; R392-K395 WeakPolarHBondContact O-CB 3.48Å; R392-K395 PolarHBondContact O-N 2.67Å; R392-E396 VanDerWaalsContact CG-OE1 3.31Å; R392-E396 WeakPolarHBondContact CG-OE1 3.37Å; R392-E396 IonicContact CZ-OE2 3.63Å; R392-E396 IonicContact NH1-OE1 3.6Å; R392-E396 PolarHBondContact NH1-OE1 3.49Å; R392-E396 IonicContact NH1-OE2 2.72Å; R392-E396 PolarHBondContact NH1-OE2 3.5Å; R392-E396 WeakPolarHBondContact O-CG 3.37Å; R392-E396 PolarHBondContact O-N 2.71Å; R392-E396 VanDerWaalsContact O-N 3.08Å
393L97.4Very high97.7Very high6 Ų629.2 Ų29.23%0.03114%0.138CC..Hα-helixtrans-59.4-46.1178.1-68.2173.4000111.6E369 Y374 Y376 F377 E389 S390 K395 E396 L397E369-L393 HydrophobicContact CB-CB 3.85Å; E369-L393 HydrophobicContact CB-CD1 4.41Å; E369-L393 HydrophobicContact CG-CB 3.64Å; E369-L393 HydrophobicContact CG-CD1 4.23Å; E369-L393 HydrophobicContact CG-CG 4.48Å; Y374-L393 HydrophobicContact CD2-CD1 3.89Å; Y374-L393 HydrophobicContact CE2-CD1 4.03Å; Y376-L393 WeakPolarHBondContact OH-CD1 3.35Å; F377-L393 HydrophobicContact CE2-CD1 3.82Å; F377-L393 HydrophobicContact CZ-CD1 3.71Å; E389-L393 HydrophobicContact CG-CD1 4.43Å; E389-L393 WeakPolarHBondContact O-CG 3.34Å; E389-L393 PolarHBondContact O-N 3.43Å; S390-L393 PolarHBondContact O-N 3.41Å; L393-K395 VanDerWaalsContact C-N 3.28Å; L393-K395 PolarHBondContact O-N 3.41Å; L393-E396 CarbonylContact O-C 3.58Å; L393-E396 PolarHBondContact O-N 3.25Å; L393-L397 PolarHBondContact O-N 3.43Å
394L97.4Very high97.7Very high1 Ų128.5 Ų28.51%0.00513%0.131CC..Hα-helixtrans-59.5-37.1176.8-72.4172.7000112.7Y140 E369 L370 S390 R392 E396 L397 L421 L430Y140-L394 HydrophobicContact CD1-CB 4.41Å; Y140-L394 HydrophobicContact CD1-CD2 4.43Å; Y140-L394 HydrophobicContact CE1-CB 4.14Å; Y140-L394 HydrophobicContact CE1-CD1 4.49Å; Y140-L394 HydrophobicContact CE1-CD2 4.13Å; Y140-L394 HydrophobicContact CE1-CG 4.5Å; E369-L394 HydrophobicContact CB-CD2 3.87Å; E369-L394 HydrophobicContact CB-CG 4.17Å; L370-L394 HydrophobicContact CB-CD2 4.49Å; L370-L394 HydrophobicContact CD1-CD1 4.11Å; S390-L394 VanDerWaalsContact O-CG 3.32Å; S390-L394 WeakPolarHBondContact O-CG 3.26Å; S390-L394 PolarHBondContact O-N 3.48Å; R392-L394 PolarHBondContact O-N 2.62Å; L394-E396 VanDerWaalsContact C-N 3.32Å; L394-L397 HydrophobicContact CD2-CD1 3.76Å; L394-L421 HydrophobicContact CD2-CD2 4.02Å; L394-L430 HydrophobicContact CD1-CD1 3.78Å; L394-L430 HydrophobicContact CD1-CD2 4.04Å; L394-L430 HydrophobicContact CD1-CG 4.38Å
395K96.1Very high97.7Very high91 Ų9123.9 Ų23.940%0.39611%0.109SC..Hα-helixtrans-68-30.5175-73.7163.5-170164.70112.9Y207 E391 R392 L393 Y398Y207-K395 HydrophobicContact CD2-CG 4.33Å; Y207-K395 HydrophobicContact CE2-CD 4.29Å; Y207-K395 HydrophobicContact CE2-CG 3.47Å; Y207-K395 VanDerWaalsContact CE2-CG 3.47Å; E391-K395 WeakPolarHBondContact O-CD 3.34Å; E391-K395 VanDerWaalsContact O-CG 3.25Å; E391-K395 WeakPolarHBondContact O-CG 3.49Å; E391-K395 PolarHBondContact O-N 3.48Å; E391-K395 VanDerWaalsContact O-N 3.1Å; R392-K395 WeakPolarHBondContact O-CB 3.48Å; R392-K395 PolarHBondContact O-N 2.67Å; L393-K395 VanDerWaalsContact C-N 3.28Å; L393-K395 PolarHBondContact O-N 3.41Å; K395-Y398 VanDerWaalsContact O-CD1 3.3Å; K395-Y398 WeakPolarHBondContact O-CD1 3.29Å; K395-Y398 WeakPolarHBondContact O-CE1 3.48Å
396E97.3Very high97.7Very high30 Ų3020.4 Ų20.414%0.149%0.093CC..Hα-helixtrans-99.7-4.2-174.7-68.3177.7-159.100113.6R392 L393 L394 Y398 L399 F400 H535R392-E396 VanDerWaalsContact CG-OE1 3.31Å; R392-E396 WeakPolarHBondContact CG-OE1 3.37Å; R392-E396 IonicContact CZ-OE2 3.63Å; R392-E396 IonicContact NH1-OE1 3.6Å; R392-E396 PolarHBondContact NH1-OE1 3.49Å; R392-E396 IonicContact NH1-OE2 2.72Å; R392-E396 PolarHBondContact NH1-OE2 3.5Å; R392-E396 WeakPolarHBondContact O-CG 3.37Å; R392-E396 PolarHBondContact O-N 2.71Å; R392-E396 VanDerWaalsContact O-N 3.08Å; L393-E396 CarbonylContact O-C 3.58Å; L393-E396 PolarHBondContact O-N 3.25Å; L394-E396 VanDerWaalsContact C-N 3.32Å; E396-Y398 PolarHBondContact O-N 3.36Å; E396-L399 WeakPolarHBondContact O-CB 3.38Å; E396-L399 PolarHBondContact O-N 2.74Å; E396-F400 HydrophobicContact CB-CD2 4.15Å; E396-F400 HydrophobicContact CB-CE2 3.99Å; E396-F400 WeakPolarHBondContact O-CD2 3.28Å; E396-F400 WeakPolarHBondContact OE2-CE2 3.45Å; E396-H535 VanDerWaalsContact CD-NE2 3.29Å; E396-H535 IonicContact OE1-CE1 2.66Å; E396-H535 IonicContact OE1-NE2 2.65Å; E396-H535 IonicContact OE2-CD2 2.68Å; E396-H535 IonicContact OE2-CE1 3.88Å; E396-H535 PolarHBondContact OE2-CE1 2.85Å; E396-H535 IonicContact OE2-NE2 3.93Å; E396-H535 PolarHBondContact OE2-NE2 3.23Å
397L97.5Very high97.8Very high2 Ų220.6 Ų20.61%0.019%0.094CC..G310 helixtrans-45.6-41.5178.8-89.3175000112.9E369 L393 L394 L399 F400 D401 V402 L421E369-L397 HydrophobicContact CB-CD2 4.5Å; E369-L397 VanDerWaalsContact CD-CD2 3.5Å; E369-L397 HydrophobicContact CG-CD2 3.65Å; E369-L397 HydrophobicContact CG-CG 4.13Å; L393-L397 PolarHBondContact O-N 3.43Å; L394-L397 HydrophobicContact CD2-CD1 3.76Å; L397-L399 PolarHBondContact O-N 2.8Å; L397-L399 VanDerWaalsContact O-N 3.13Å; L397-F400 CarbonylContact O-C 3.54Å; L397-F400 PolarHBondContact O-N 3.47Å; L397-D401 HydrophobicContact CD2-CB 3.98Å; L397-D401 PolarHBondContact O-N 2.89Å; L397-V402 HydrophobicContact CB-CB 4.2Å; L397-V402 HydrophobicContact CB-CG2 3.9Å; L397-V402 HydrophobicContact CD1-CG2 4.34Å; L397-V402 HydrophobicContact CD2-CG2 4.2Å; L397-V402 HydrophobicContact CG-CG2 4.4Å; L397-V402 WeakPolarHBondContact O-CB 3.44Å; L397-V402 PolarHBondContact O-N 2.75Å; L397-L421 HydrophobicContact CD1-CD1 3.91Å; L397-L421 HydrophobicContact CD1-CD2 3.59Å; L397-L421 HydrophobicContact CD1-CG 4.41Å
398Y98.3Very high97.8Very high37 Ų3720.2 Ų20.215%0.1459%0.091CC..G310 helixtrans-64.6-12.4-178.684.9-81.9000115P179 P182 K395 E396 L403P179-Y398 HydrophobicContact CB-CE2 4.07Å; P182-Y398 HydrophobicContact CG-CD1 3.48Å; P182-Y398 VanDerWaalsContact CG-CD1 3.48Å; P182-Y398 HydrophobicContact CG-CD2 4.12Å; P182-Y398 HydrophobicContact CG-CE1 4.05Å; P182-Y398 HydrophobicContact CG-CG 3.5Å; K395-Y398 VanDerWaalsContact O-CD1 3.3Å; K395-Y398 WeakPolarHBondContact O-CD1 3.29Å; K395-Y398 WeakPolarHBondContact O-CE1 3.48Å; E396-Y398 PolarHBondContact O-N 3.36Å; Y398-L403 WeakPolarHBondContact O-CB 3.42Å
399L98.3Very high97.9Very high9 Ų914.5 Ų14.55%0.0476%0.064CC..G310 helixtrans-95.2-21.9174.5-62.3171.1000112.3E396 L397 P534E396-L399 WeakPolarHBondContact O-CB 3.38Å; E396-L399 PolarHBondContact O-N 2.74Å; L397-L399 PolarHBondContact O-N 2.8Å; L397-L399 VanDerWaalsContact O-N 3.13Å; L399-P534 HydrophobicContact CD1-CG 3.74Å
400F98Very high97.9Very high4 Ų414.5 Ų14.52%0.0186%0.064CC..THydrogen-bonded Turntrans-125-104.1-169-54.7-62000111.5D335 E396 L397 V402 L403 R404 L533 H535 W537D335-F400 HydrophobicContact CB-CD1 4.47Å; D335-F400 HydrophobicContact CB-CE1 4.39Å; E396-F400 HydrophobicContact CB-CD2 4.15Å; E396-F400 HydrophobicContact CB-CE2 3.99Å; E396-F400 WeakPolarHBondContact O-CD2 3.28Å; E396-F400 WeakPolarHBondContact OE2-CE2 3.45Å; L397-F400 CarbonylContact O-C 3.54Å; L397-F400 PolarHBondContact O-N 3.47Å; F400-V402 PolarHBondContact O-N 3.44Å; F400-L403 WeakPolarHBondContact O-CA 3.45Å; F400-L403 WeakPolarHBondContact O-CB 3.43Å; F400-L403 PolarHBondContact O-N 3.39Å; F400-L403 VanDerWaalsContact O-N 3.09Å; F400-R404 PolarHBondContact O-N 3.04Å; F400-L533 HydrophobicContact CE1-CD1 3.88Å; F400-L533 HydrophobicContact CZ-CD1 4.4Å; F400-H535 AromaticContact CE2-NE2 3.95Å; F400-H535 AromaticContact CZ-CD2 3.88Å; F400-H535 AromaticContact CZ-NE2 3.85Å; F400-W537 HydrophobicContact CD1-CB 3.74Å; F400-W537 HydrophobicContact CD1-CG 4.39Å; F400-W537 AromaticContact CD2-CD1 3.7Å; F400-W537 HydrophobicContact CE1-CB 3.58Å; F400-W537 HydrophobicContact CE2-CB 4.38Å; F400-W537 HydrophobicContact CG-CB 4.22Å; F400-W537 AromaticContact CG-CD1 3.79Å; F400-W537 HydrophobicContact CG-CG 4.39Å; F400-W537 HydrophobicContact CZ-CB 3.92Å
401D97.6Very high98Very high21 Ų2115.1 Ų15.111%0.1127%0.069CC..Hα-helixtrans-61.6-41.5-171-68.9-91.6000114E365 L397 R404 A405E365-D401 HydrophobicContact CG-CB 4.4Å; L397-D401 HydrophobicContact CD2-CB 3.98Å; L397-D401 PolarHBondContact O-N 2.89Å; D401-R404 PolarHBondContact O-N 3.37Å; D401-R404 IonicContact OD1-CZ 3.67Å; D401-R404 IonicContact OD1-NH2 3.84Å; D401-R404 PolarHBondContact OD1-NH2 3.17Å; D401-A405 VanDerWaalsContact O-CB 3.25Å; D401-A405 WeakPolarHBondContact O-CB 3.48Å; D401-A405 PolarHBondContact O-N 3.4Å
402V98Very high98.1Very high2 Ų215 Ų151%0.0127%0.069CC..Hα-helixtrans-71.6-33.7176.1160.10000111.2G141 V142 L397 F400 A405 D406 L421G141-V402 WeakPolarHBondContact O-CG1 3.28Å; V142-V402 VanDerWaalsContact CA-CG1 3.47Å; V142-V402 HydrophobicContact CB-CG1 4.48Å; L397-V402 HydrophobicContact CB-CB 4.2Å; L397-V402 HydrophobicContact CB-CG2 3.9Å; L397-V402 HydrophobicContact CD1-CG2 4.34Å; L397-V402 HydrophobicContact CD2-CG2 4.2Å; L397-V402 HydrophobicContact CG-CG2 4.4Å; L397-V402 WeakPolarHBondContact O-CB 3.44Å; L397-V402 PolarHBondContact O-N 2.75Å; F400-V402 PolarHBondContact O-N 3.44Å; V402-A405 PolarHBondContact O-N 3.16Å; V402-D406 WeakPolarHBondContact O-CB 3.25Å; V402-D406 PolarHBondContact O-N 3.09Å; V402-L421 HydrophobicContact CG2-CD1 3.71Å
403L98.7Very high98.2Very high13 Ų1313.1 Ų13.17%0.0686%0.062CC..Hα-helixtrans-60.9-53171.9-179.5154.9000110.2L331 T333 T338 Y398 F400 A405 D406 R407L331-L403 HydrophobicContact CB-CD2 4.03Å; L331-L403 HydrophobicContact CD2-CD2 3.52Å; L331-L403 HydrophobicContact CG-CD2 4.36Å; L331-L403 WeakPolarHBondContact O-CD2 3.39Å; T333-L403 HydrophobicContact CG2-CD1 4.35Å; T333-L403 HydrophobicContact CG2-CD2 3.83Å; T338-L403 HydrophobicContact CG2-CD2 4.08Å; Y398-L403 WeakPolarHBondContact O-CB 3.42Å; F400-L403 WeakPolarHBondContact O-CA 3.45Å; F400-L403 WeakPolarHBondContact O-CB 3.43Å; F400-L403 PolarHBondContact O-N 3.39Å; F400-L403 VanDerWaalsContact O-N 3.09Å; L403-A405 VanDerWaalsContact C-N 3.34Å; L403-A405 PolarHBondContact O-N 3.03Å; L403-D406 PolarHBondContact O-N 3.16Å; L403-R407 HydrophobicContact CD2-CG 4.21Å; L403-R407 HydrophobicContact CG-CG 4.26Å; L403-R407 WeakPolarHBondContact O-CB 3.36Å; L403-R407 VanDerWaalsContact O-CG 3.25Å; L403-R407 WeakPolarHBondContact O-CG 3.32Å; L403-R407 PolarHBondContact O-N 3.1Å
404R98.6Very high98.2Very high14 Ų1412.8 Ų12.85%0.0536%0.061CC..Hα-helixtrans-53.2-52.9175.8162.9174.965.369.41.7110.9L331 T338 S342 M345 E365 F400 D401 D406 R407 T408L331-R404 HydrophobicContact CD2-CB 4.35Å; T338-R404 HydrophobicContact CG2-CB 4.02Å; S342-R404 WeakPolarHBondContact OG-CB 3.3Å; S342-R404 WeakPolarHBondContact OG-CD 3.35Å; S342-R404 WeakPolarHBondContact OG-CG 3.41Å; M345-R404 HydrophobicContact SD-CG 3.86Å; M345-R404 PolarHBondContact SD-NH1 2.93Å; E365-R404 IonicContact OE1-CZ 3.1Å; E365-R404 IonicContact OE1-NH1 2.55Å; E365-R404 PolarHBondContact OE1-NH1 3.39Å; E365-R404 IonicContact OE1-NH2 3.43Å; E365-R404 PolarHBondContact OE1-NH2 3.42Å; F400-R404 PolarHBondContact O-N 3.04Å; D401-R404 PolarHBondContact O-N 3.37Å; D401-R404 IonicContact OD1-CZ 3.67Å; D401-R404 IonicContact OD1-NH2 3.84Å; D401-R404 PolarHBondContact OD1-NH2 3.17Å; R404-D406 PolarHBondContact O-N 2.94Å; R404-R407 PolarHBondContact O-N 3.23Å; R404-T408 HydrophobicContact CG-CG2 4.47Å; R404-T408 WeakPolarHBondContact O-CB 3.19Å; R404-T408 WeakPolarHBondContact O-CG2 3.46Å; R404-T408 PolarHBondContact O-N 2.89Å; R404-T408 PolarHBondContact O-OG1 2.86Å
405A98.5Very high98.3Very high0 Ų013 Ų130%06%0.061CC..Hα-helixtrans-63.7-42.1-173.700000112.2M345 E365 D401 V402 L403 T409 L416M345-A405 HydrophobicContact CE-CB 3.7Å; M345-A405 HydrophobicContact SD-CB 4.19Å; E365-A405 HydrophobicContact CG-CB 4.06Å; D401-A405 VanDerWaalsContact O-CB 3.25Å; D401-A405 WeakPolarHBondContact O-CB 3.48Å; D401-A405 PolarHBondContact O-N 3.4Å; V402-A405 PolarHBondContact O-N 3.16Å; L403-A405 VanDerWaalsContact C-N 3.34Å; L403-A405 PolarHBondContact O-N 3.03Å; A405-T409 WeakPolarHBondContact O-CB 3.36Å; A405-T409 WeakPolarHBondContact O-CG2 3.29Å; A405-T409 PolarHBondContact O-OG1 3.08Å; A405-L416 HydrophobicContact CB-CD1 4.16Å; A405-L416 HydrophobicContact CB-CD2 3.39Å; A405-L416 HydrophobicContact CB-CG 4.4Å
406D98.8Very high98.4Very high1 Ų18.7 Ų8.71%0.0054%0.043CC..Hα-helixtrans-68-54.2175.417298.6000111.8M1 R27 P144 V402 L403 R404 T408 T409 A410M1-D406 HydrophobicContact CE-CB 3.92Å; M1-D406 WeakPolarHBondContact CE-O 3.31Å; M1-D406 WeakPolarHBondContact CE-OD1 3.24Å; R27-D406 IonicContact CZ-OD1 3Å; R27-D406 IonicContact CZ-OD2 3.14Å; R27-D406 IonicContact NH1-OD1 3.11Å; R27-D406 IonicContact NH1-OD2 2.74Å; R27-D406 PolarHBondContact NH1-OD2 2.98Å; R27-D406 IonicContact NH2-OD1 3.81Å; R27-D406 PolarHBondContact NH2-OD1 2.96Å; R27-D406 IonicContact NH2-OD2 3.18Å; R27-D406 PolarHBondContact NH2-OD2 3.25Å; R27-D406 VanDerWaalsContact NH2-OD2 3.14Å; P144-D406 VanDerWaalsContact CD-CG 3.5Å; P144-D406 WeakPolarHBondContact CD-OD1 3.41Å; P144-D406 WeakPolarHBondContact CG-OD2 3.34Å; V402-D406 WeakPolarHBondContact O-CB 3.25Å; V402-D406 PolarHBondContact O-N 3.09Å; L403-D406 PolarHBondContact O-N 3.16Å; R404-D406 PolarHBondContact O-N 2.94Å; D406-T408 PolarHBondContact O-N 3.04Å; D406-T409 PolarHBondContact O-N 2.71Å; D406-T409 PolarHBondContact O-OG1 3.26Å; D406-A410 WeakPolarHBondContact O-CB 3.27Å; D406-A410 PolarHBondContact O-N 3.45Å
407R98.8Very high98.5Very high4 Ų47.3 Ų7.32%0.0154%0.036CC..Hα-helixtrans-65.2-42.7-170.6-64.8-57.8179.8-63.9-17.5112.4P144 S330 L331 E332 L403 R404 A411P144-R407 VanDerWaalsContact CB-CZ 3.43Å; P144-R407 VanDerWaalsContact CB-NH2 3.29Å; P144-R407 VanDerWaalsContact CG-NH1 3.3Å; S330-R407 WeakPolarHBondContact O-CB 3.18Å; S330-R407 WeakPolarHBondContact O-CD 3.36Å; S330-R407 WeakPolarHBondContact O-CG 3.16Å; L331-R407 HydrophobicContact CD2-CB 4.18Å; E332-R407 IonicContact OE2-NE 2.66Å; L403-R407 HydrophobicContact CD2-CG 4.21Å; L403-R407 HydrophobicContact CG-CG 4.26Å; L403-R407 WeakPolarHBondContact O-CB 3.36Å; L403-R407 VanDerWaalsContact O-CG 3.25Å; L403-R407 WeakPolarHBondContact O-CG 3.32Å; L403-R407 PolarHBondContact O-N 3.1Å; R404-R407 PolarHBondContact O-N 3.23Å; R407-A411 VanDerWaalsContact O-CB 3.28Å; R407-A411 WeakPolarHBondContact O-CB 3.47Å; R407-A411 PolarHBondContact O-N 2.87Å
408T98.8Very high98.6Very high0 Ų07.2 Ų7.20%04%0.036CC..Hα-helixtrans-72.1-34.4-176.7590000112.9L331 M345 S349 R404 D406L331-T408 HydrophobicContact CD2-CG2 4.21Å; M345-T408 HydrophobicContact CB-CG2 4.39Å; M345-T408 VanDerWaalsContact CG-OG1 3.24Å; M345-T408 WeakPolarHBondContact CG-OG1 3.47Å; M345-T408 PolarHBondContact SD-OG1 3Å; M345-T408 VanDerWaalsContact SD-OG1 3.38Å; S349-T408 WeakPolarHBondContact CB-O 3.42Å; S349-T408 PolarHBondContact OG-O 3.45Å; R404-T408 HydrophobicContact CG-CG2 4.47Å; R404-T408 WeakPolarHBondContact O-CB 3.19Å; R404-T408 WeakPolarHBondContact O-CG2 3.46Å; R404-T408 PolarHBondContact O-N 2.89Å; R404-T408 PolarHBondContact O-OG1 2.86Å; D406-T408 PolarHBondContact O-N 3.04Å
409T98.8Very high98.6Very high0 Ų05.5 Ų5.50%03%0.029CC..Hα-helixtrans-76-42.2174.457.80000111.5M1 M345 A405 D406 A411 H412 L414 L416M1-T409 VanDerWaalsContact CE-OG1 3.23Å; M1-T409 WeakPolarHBondContact CE-OG1 3.1Å; M345-T409 HydrophobicContact CE-CG2 4.04Å; A405-T409 WeakPolarHBondContact O-CB 3.36Å; A405-T409 WeakPolarHBondContact O-CG2 3.29Å; A405-T409 PolarHBondContact O-OG1 3.08Å; D406-T409 PolarHBondContact O-N 2.71Å; D406-T409 PolarHBondContact O-OG1 3.26Å; T409-A411 VanDerWaalsContact C-N 3.32Å; T409-A411 PolarHBondContact O-N 2.96Å; T409-H412 PolarHBondContact O-N 3.25Å; T409-L414 WeakPolarHBondContact O-CB 3.42Å; T409-L414 PolarHBondContact O-N 2.85Å; T409-L414 VanDerWaalsContact O-N 3.1Å; T409-L416 HydrophobicContact CG2-CD1 4.5Å
410A98.8Very high98.6Very high0 Ų05 Ų50%03%0.027CC..Hα-helixtrans-67.6-29.9178.200000113M1 H26 R27 D406 H412 G413M1-A410 HydrophobicContact CB-CB 4.3Å; M1-A410 HydrophobicContact CE-CB 3.78Å; H26-A410 CarbonylContact C-O 3.51Å; H26-A410 VanDerWaalsContact O-O 3.06Å; R27-A410 WeakPolarHBondContact CA-O 3.37Å; R27-A410 HydrophobicContact CB-CB 4.42Å; R27-A410 HydrophobicContact CG-CB 4.06Å; R27-A410 VanDerWaalsContact NH1-CB 3.26Å; D406-A410 WeakPolarHBondContact O-CB 3.27Å; D406-A410 PolarHBondContact O-N 3.45Å; A410-H412 PolarHBondContact O-N 3.08Å; A410-G413 PolarHBondContact O-N 2.85Å
411A98.8Very high98.6Very high13 Ų135 Ų511%0.1073%0.027CC..THydrogen-bonded Turntrans-53.5-22.8172.700000113.4Y346 R407 T409Y346-A411 HydrophobicContact CD2-CB 3.97Å; Y346-A411 HydrophobicContact CE2-CB 3.57Å; R407-A411 VanDerWaalsContact O-CB 3.28Å; R407-A411 WeakPolarHBondContact O-CB 3.47Å; R407-A411 PolarHBondContact O-N 2.87Å; T409-A411 VanDerWaalsContact C-N 3.32Å; T409-A411 PolarHBondContact O-N 2.96Å
412H98.7Very high98.6Very high25 Ų254 Ų412%0.1162%0.021CC..THydrogen-bonded Turntrans-118.218.2179.2-59.4-58.9000113.6Y346 K350 R353 T409 A410 L414Y346-H412 AromaticContact CD1-NE2 3.76Å; Y346-H412 AromaticContact CD2-NE2 3.58Å; Y346-H412 AromaticContact CE1-CE1 3.96Å; Y346-H412 AromaticContact CE1-NE2 3.57Å; Y346-H412 AromaticContact CE2-CE1 3.92Å; Y346-H412 AromaticContact CE2-NE2 3.36Å; Y346-H412 WeakPolarHBondContact CE2-NE2 3.45Å; Y346-H412 AromaticContact CG-NE2 3.77Å; Y346-H412 AromaticContact CZ-CE1 3.59Å; Y346-H412 AromaticContact CZ-NE2 3.35Å; Y346-H412 VanDerWaalsContact CZ-NE2 3.35Å; Y346-H412 PolarHBondContact O-CD2 2.73Å; Y346-H412 PolarHBondContact O-NE2 2.83Å; K350-H412 PolarHBondContact N-CD2 3.49Å; R353-H412 HydrophobicContact CB-CB 4.02Å; R353-H412 WeakPolarHBondContact CB-O 3.41Å; R353-H412 WeakPolarHBondContact CD-O 3.28Å; R353-H412 HydrophobicContact CG-CB 4.48Å; R353-H412 VanDerWaalsContact CG-O 3.24Å; R353-H412 WeakPolarHBondContact CG-O 3.39Å; R353-H412 PolarHBondContact NH1-O 2.88Å; T409-H412 PolarHBondContact O-N 3.25Å; A410-H412 PolarHBondContact O-N 3.08Å; H412-L414 VanDerWaalsContact C-N 3.34Å; H412-L414 PolarHBondContact O-N 2.77Å
413G98.5Very high98.5Very high2 Ų24.3 Ų4.32%0.0212%0.023CC..THydrogen-bonded Turntrans66.834176.400000113.6H26 R27 L50 A410H26-G413 VanDerWaalsContact O-CA 3.31Å; H26-G413 WeakPolarHBondContact O-CA 3.27Å; H26-G413 PolarHBondContact O-N 2.94Å; R27-G413 WeakPolarHBondContact O-CA 3.47Å; L50-G413 VanDerWaalsContact CD1-O 3.29Å; L50-G413 WeakPolarHBondContact CD1-O 3.2Å; L50-G413 WeakPolarHBondContact CD2-O 3.32Å; A410-G413 PolarHBondContact O-N 2.85Å
414L98.9Very high98.3Very high0 Ų04.4 Ų4.40%02%0.022CC..  trans-103.5158.3174.1-54.7176.3000110.4M1 S349 I352 R353 S358 I361 T409 H412M1-L414 WeakPolarHBondContact CG-O 3.42Å; M1-L414 PolarHBondContact N-O 2.86Å; S349-L414 WeakPolarHBondContact O-CD1 3.37Å; I352-L414 HydrophobicContact CB-CD1 3.81Å; I352-L414 HydrophobicContact CD1-CD1 4.28Å; I352-L414 HydrophobicContact CG2-CD1 3.69Å; I352-L414 HydrophobicContact CG2-CD2 3.9Å; I352-L414 HydrophobicContact CG2-CG 4.48Å; R353-L414 HydrophobicContact CB-CD2 4.35Å; S358-L414 WeakPolarHBondContact O-CD2 3.12Å; I361-L414 HydrophobicContact CG1-CB 4.19Å; I361-L414 HydrophobicContact CG1-CD1 4.17Å; T409-L414 WeakPolarHBondContact O-CB 3.42Å; T409-L414 PolarHBondContact O-N 2.85Å; T409-L414 VanDerWaalsContact O-N 3.1Å; H412-L414 VanDerWaalsContact C-N 3.34Å; H412-L414 PolarHBondContact O-N 2.77Å
415E98.8Very high98.2Very high5 Ų53.7 Ų3.72%0.0232%0.019CC..EExtended strand (participates in β ladder)trans-107.8122175179-179.892.300112.4M1 L50 V52 E77 R143 V359 V360 I361 R417M1-E415 HydrophobicContact CG-CB 4.14Å; M1-E415 HydrophobicContact CG-CG 4.05Å; L50-E415 HydrophobicContact CD2-CB 4.07Å; V52-E415 HydrophobicContact CG2-CB 4.34Å; E77-E415 WeakPolarHBondContact CG-OE2 3.4Å; R143-E415 IonicContact NH2-OE2 3.04Å; V359-E415 PolarHBondContact O-N 2.79Å; V360-E415 CarbonylContact C-O 2.77Å; I361-E415 PolarHBondContact N-O 2.89Å; E415-R417 IonicContact OE1-CZ 3.74Å; E415-R417 IonicContact OE1-NE 3.68Å; E415-R417 PolarHBondContact OE1-NE 2.68Å; E415-R417 IonicContact OE1-NH2 3.71Å; E415-R417 PolarHBondContact OE1-NH2 2.72Å
416L98.8Very high98.1Very high0 Ų03.7 Ų3.70%02%0.019CC..EExtended strand (participates in β ladder)trans-80.6135173.2-17874.4000112.4M1 R143 M345 I361 A405 T409 V418M1-L416 HydrophobicContact CE-CB 3.94Å; M1-L416 HydrophobicContact SD-CB 4.35Å; R143-L416 PolarHBondContact NH1-O 3.44Å; R143-L416 VanDerWaalsContact NH1-O 3.09Å; R143-L416 PolarHBondContact NH2-O 3.19Å; M345-L416 HydrophobicContact CE-CD1 4.39Å; I361-L416 WeakPolarHBondContact O-CA 3.5Å; A405-L416 HydrophobicContact CB-CD1 4.16Å; A405-L416 HydrophobicContact CB-CD2 3.39Å; A405-L416 HydrophobicContact CB-CG 4.4Å; T409-L416 HydrophobicContact CG2-CD1 4.5Å; L416-V418 HydrophobicContact CD1-CG1 4.08Å; L416-V418 HydrophobicContact CD2-CG1 3.92Å; L416-V418 HydrophobicContact CG-CG1 3.94Å
417R98.8Very high98Very high1 Ų14 Ų40%0.0042%0.021CC..EExtended strand (participates in β ladder)trans-126.3127.3164.8-62.2-169.2-175.8-155.3-7.2111.4E77 R246 M248 V360 I361 F362 S363 E415E77-R417 IonicContact OE1-NH2 2.67Å; E77-R417 IonicContact OE2-CZ 3.82Å; E77-R417 IonicContact OE2-NH2 3.89Å; E77-R417 PolarHBondContact OE2-NH2 3.13Å; R246-R417 WeakPolarHBondContact O-CD 3.07Å; R246-R417 PolarHBondContact O-NH1 3.41Å; M248-R417 VanDerWaalsContact O-CZ 3.24Å; M248-R417 PolarHBondContact O-NH1 3.35Å; M248-R417 PolarHBondContact O-NH2 3.45Å; V360-R417 VanDerWaalsContact CG1-CD 3.45Å; V360-R417 HydrophobicContact CG1-CG 3.91Å; I361-R417 PolarHBondContact O-N 2.93Å; F362-R417 WeakPolarHBondContact CA-O 3.37Å; F362-R417 HydrophobicContact CD1-CB 4.3Å; F362-R417 HydrophobicContact CD2-CB 4.28Å; F362-R417 HydrophobicContact CE1-CB 4.36Å; F362-R417 HydrophobicContact CE2-CB 4.34Å; F362-R417 HydrophobicContact CG-CB 4.29Å; F362-R417 HydrophobicContact CZ-CB 4.41Å; S363-R417 PolarHBondContact N-O 3.47Å; E415-R417 IonicContact OE1-CZ 3.74Å; E415-R417 IonicContact OE1-NE 3.68Å; E415-R417 PolarHBondContact OE1-NE 2.68Å; E415-R417 IonicContact OE1-NH2 3.71Å; E415-R417 PolarHBondContact OE1-NH2 2.72Å
418V98.7Very high97.8Very high1 Ų15.1 Ų5.11%0.0063%0.026CC..  trans-123.790.3-174.5-76.30000110V142 E365 L416 F420 L421V142-V418 HydrophobicContact CG1-CG2 3.81Å; V142-V418 HydrophobicContact CG2-CG2 4.07Å; E365-V418 HydrophobicContact CB-CG1 3.97Å; L416-V418 HydrophobicContact CD1-CG1 4.08Å; L416-V418 HydrophobicContact CD2-CG1 3.92Å; L416-V418 HydrophobicContact CG-CG1 3.94Å; V418-F420 VanDerWaalsContact C-N 3.29Å; V418-F420 PolarHBondContact O-N 3.41Å; V418-L421 HydrophobicContact CB-CD1 4.5Å; V418-L421 HydrophobicContact CG2-CB 4.27Å; V418-L421 HydrophobicContact CG2-CD1 3.95Å; V418-L421 HydrophobicContact CG2-CG 4.37Å; V418-L421 PolarHBondContact O-N 2.85Å
419P98.8Very high97.7Very high0 Ų05.1 Ų5.10%03%0.026CC..G310 helixtrans-67.7-23.6-174.727-35.3000114.1F239 A242 V243 V266 F362 S363 L421 D422F239-P419 HydrophobicContact CE2-CB 4.39Å; F239-P419 HydrophobicContact CE2-CG 4.36Å; F239-P419 HydrophobicContact CZ-CG 4.45Å; A242-P419 HydrophobicContact CB-CB 4.09Å; A242-P419 WeakPolarHBondContact CB-O 3.33Å; V243-P419 HydrophobicContact CG2-CB 3.69Å; V243-P419 HydrophobicContact CG2-CG 3.91Å; V266-P419 HydrophobicContact CG1-CG 4.13Å; V266-P419 HydrophobicContact CG2-CG 3.72Å; F362-P419 HydrophobicContact CD1-CG 4.45Å; S363-P419 WeakPolarHBondContact O-CD 3.43Å; P419-L421 PolarHBondContact O-N 3.3Å; P419-D422 VanDerWaalsContact O-CB 3.26Å; P419-D422 WeakPolarHBondContact O-CB 3.45Å; P419-D422 PolarHBondContact O-N 2.76Å; P419-D422 VanDerWaalsContact O-N 3.1Å
420F98.8Very high97.6Very high0 Ų05.7 Ų5.70%03%0.029CC..G310 helixtrans-64.6-20.7174.9-80.5-79000113.5F239 D262 V266 S367 V418 D422 F425 T426 L448F239-F420 HydrophobicContact CD2-CD1 4.32Å; F239-F420 HydrophobicContact CD2-CE1 4.16Å; F239-F420 HydrophobicContact CD2-CZ 4.43Å; F239-F420 AromaticContact CE2-CD1 3.76Å; F239-F420 HydrophobicContact CE2-CD1 3.76Å; F239-F420 AromaticContact CE2-CD2 3.78Å; F239-F420 HydrophobicContact CE2-CD2 3.78Å; F239-F420 AromaticContact CE2-CE1 3.56Å; F239-F420 HydrophobicContact CE2-CE1 3.56Å; F239-F420 AromaticContact CE2-CE2 3.61Å; F239-F420 HydrophobicContact CE2-CE2 3.61Å; F239-F420 AromaticContact CE2-CG 3.85Å; F239-F420 HydrophobicContact CE2-CG 3.85Å; F239-F420 AromaticContact CE2-CZ 3.48Å; F239-F420 HydrophobicContact CE2-CZ 3.48Å; F239-F420 VanDerWaalsContact CE2-CZ 3.48Å; F239-F420 HydrophobicContact CZ-CD2 4.16Å; F239-F420 HydrophobicContact CZ-CE1 4.13Å; F239-F420 AromaticContact CZ-CE2 3.61Å; F239-F420 HydrophobicContact CZ-CE2 3.61Å; F239-F420 AromaticContact CZ-CZ 3.58Å; F239-F420 HydrophobicContact CZ-CZ 3.58Å; D262-F420 HydrophobicContact CB-CE2 3.78Å; D262-F420 HydrophobicContact CB-CZ 4.14Å; V266-F420 HydrophobicContact CG2-CD2 4.06Å; V266-F420 HydrophobicContact CG2-CE2 3.71Å; S367-F420 WeakPolarHBondContact OG-CE1 3.44Å; V418-F420 VanDerWaalsContact C-N 3.29Å; V418-F420 PolarHBondContact O-N 3.41Å; F420-D422 VanDerWaalsContact C-N 3.34Å; F420-F425 AromaticContact CD1-CE1 3.73Å; F420-F425 HydrophobicContact CD1-CE1 3.73Å; F420-F425 HydrophobicContact CD1-CZ 4.33Å; F420-F425 HydrophobicContact CE1-CE1 4.28Å; F420-F425 HydrophobicContact CE1-CZ 4.44Å; F420-T426 WeakPolarHBondContact O-CG2 3.34Å; F420-L448 HydrophobicContact CE1-CD1 4.25Å; F420-L448 HydrophobicContact CE1-CD2 3.89Å; F420-L448 HydrophobicContact CZ-CD2 4.18Å
421L98.2Very high97.4Very high4 Ų48.4 Ų8.42%0.0215%0.048CC..G310 helixtrans-96.219175.5-60.8-178.5000112.9Y140 V142 L394 L397 V402 V418 P419 H423Y140-L421 HydrophobicContact CD1-CD2 4.44Å; Y140-L421 HydrophobicContact CD2-CB 3.93Å; Y140-L421 HydrophobicContact CD2-CD2 4.32Å; Y140-L421 HydrophobicContact CE2-CB 4.42Å; Y140-L421 HydrophobicContact CG-CB 4.46Å; Y140-L421 HydrophobicContact CG-CD2 4.22Å; V142-L421 HydrophobicContact CG2-CD1 3.87Å; L394-L421 HydrophobicContact CD2-CD2 4.02Å; L397-L421 HydrophobicContact CD1-CD1 3.91Å; L397-L421 HydrophobicContact CD1-CD2 3.59Å; L397-L421 HydrophobicContact CD1-CG 4.41Å; V402-L421 HydrophobicContact CG2-CD1 3.71Å; V418-L421 HydrophobicContact CB-CD1 4.5Å; V418-L421 HydrophobicContact CG2-CB 4.27Å; V418-L421 HydrophobicContact CG2-CD1 3.95Å; V418-L421 HydrophobicContact CG2-CG 4.37Å; V418-L421 PolarHBondContact O-N 2.85Å; P419-L421 PolarHBondContact O-N 3.3Å; L421-H423 PolarHBondContact O-N 3.35Å
422D97.8Very high97.3Very high0 Ų08 Ų80%04%0.044CC..  trans-64.7129.7171.3-176.9-88.4000111.4A242 K245 R246 P419 F420 R424 F425 T426A242-D422 HydrophobicContact CB-CB 3.4Å; K245-D422 WeakPolarHBondContact CD-OD2 3.11Å; K245-D422 VanDerWaalsContact CE-OD2 3.26Å; K245-D422 WeakPolarHBondContact CE-OD2 3.24Å; K245-D422 IonicContact NZ-OD1 3.73Å; K245-D422 PolarHBondContact NZ-OD1 3.08Å; K245-D422 IonicContact NZ-OD2 2.73Å; K245-D422 PolarHBondContact NZ-OD2 3.36Å; R246-D422 IonicContact CZ-OD2 2.76Å; R246-D422 IonicContact NH1-OD2 3.91Å; R246-D422 PolarHBondContact NH1-OD2 2.92Å; R246-D422 VanDerWaalsContact NH2-CA 3.32Å; R246-D422 IonicContact NH2-OD2 3.48Å; R246-D422 PolarHBondContact NH2-OD2 3.43Å; P419-D422 VanDerWaalsContact O-CB 3.26Å; P419-D422 WeakPolarHBondContact O-CB 3.45Å; P419-D422 PolarHBondContact O-N 2.76Å; P419-D422 VanDerWaalsContact O-N 3.1Å; F420-D422 VanDerWaalsContact C-N 3.34Å; D422-R424 VanDerWaalsContact C-N 3.31Å; D422-R424 PolarHBondContact O-N 3.29Å; D422-R424 PolarHBondContact OD1-N 3.49Å; D422-R424 VanDerWaalsContact OD1-N 3.13Å; D422-F425 HydrophobicContact CB-CB 3.95Å; D422-F425 PolarHBondContact O-N 3.28Å; D422-F425 VanDerWaalsContact O-N 3.11Å; D422-F425 PolarHBondContact OD1-N 3.33Å; D422-T426 WeakPolarHBondContact O-CG2 3.38Å; D422-T426 PolarHBondContact O-N 3.09Å; D422-T426 PolarHBondContact O-OG1 2.88Å
423H95.7Very high97.2Very high8 Ų89 Ų94%0.0375%0.053CC..Hα-helixtrans-55.9-41.7-171.9-59.1139.5000113.4D118 G119 T139 P211 H213 L421 T426 S427D118-H423 IonicContact OD1-ND1 3.89Å; D118-H423 PolarHBondContact OD1-ND1 2.93Å; G119-H423 PolarHBondContact O-CE1 3.15Å; T139-H423 WeakPolarHBondContact CB-NE2 3.49Å; T139-H423 PolarHBondContact OG1-CD2 2.88Å; T139-H423 PolarHBondContact OG1-NE2 3.11Å; P211-H423 HydrophobicContact CB-CB 4.33Å; P211-H423 HydrophobicContact CG-CB 3.85Å; H213-H423 AromaticContact CE1-ND1 3.77Å; H213-H423 AromaticContact NE2-CG 3.68Å; H213-H423 AromaticContact NE2-ND1 3.11Å; H213-H423 PolarHBondContact NE2-ND1 3.06Å; H213-H423 VanDerWaalsContact NE2-ND1 3.11Å; L421-H423 PolarHBondContact O-N 3.35Å; H423-T426 PolarHBondContact O-OG1 3.41Å; H423-T426 VanDerWaalsContact O-OG1 3.12Å; H423-S427 VanDerWaalsContact O-CB 3.25Å; H423-S427 WeakPolarHBondContact O-CB 3.26Å; H423-S427 PolarHBondContact O-N 2.78Å; H423-S427 PolarHBondContact O-OG 2.95Å
424R94.3Very high97.2Very high14 Ų149.6 Ų9.65%0.0536%0.057CC..Hα-helixtrans-76.3-37.3179.9-72.2-176.179.6-165.85.7111.7E210 P211 A214 D217 V219 L238 D422 Y428E210-R424 IonicContact OE1-NE 3.79Å; E210-R424 IonicContact OE1-NH2 2.92Å; P211-R424 HydrophobicContact CG-CG 4.03Å; A214-R424 HydrophobicContact CB-CG 3.94Å; D217-R424 IonicContact OD1-NH1 3.57Å; D217-R424 WeakPolarHBondContact OD2-CD 3.45Å; D217-R424 IonicContact OD2-CZ 2.72Å; D217-R424 IonicContact OD2-NE 2.98Å; D217-R424 IonicContact OD2-NH1 3.59Å; D217-R424 PolarHBondContact OD2-NH1 3.25Å; V219-R424 PolarHBondContact O-NH1 3.06Å; V219-R424 PolarHBondContact O-NH2 3.47Å; L238-R424 HydrophobicContact CD2-CB 4.2Å; D422-R424 VanDerWaalsContact C-N 3.31Å; D422-R424 PolarHBondContact O-N 3.29Å; D422-R424 PolarHBondContact OD1-N 3.49Å; D422-R424 VanDerWaalsContact OD1-N 3.13Å; R424-Y428 VanDerWaalsContact O-CB 3.26Å; R424-Y428 WeakPolarHBondContact O-CB 3.32Å; R424-Y428 PolarHBondContact O-N 2.98Å
425F96.7Very high97.1Very high0 Ų014.2 Ų14.20%08%0.079CC..Hα-helixtrans-61.7-47.8175.8-178.1-105.2000111.5I235 L238 F239 L370 F420 D422 Y429I235-F425 HydrophobicContact CG2-CE2 4.07Å; I235-F425 HydrophobicContact CG2-CZ 4.48Å; L238-F425 HydrophobicContact CB-CB 4.39Å; L238-F425 HydrophobicContact CB-CD2 3.85Å; F239-F425 HydrophobicContact CB-CD2 4.01Å; F239-F425 HydrophobicContact CB-CE2 3.74Å; F239-F425 HydrophobicContact CB-CZ 4.39Å; F239-F425 HydrophobicContact CD2-CD2 4.44Å; F239-F425 HydrophobicContact CD2-CE1 4.21Å; F239-F425 HydrophobicContact CD2-CE2 4.11Å; F239-F425 AromaticContact CD2-CZ 3.99Å; F239-F425 HydrophobicContact CD2-CZ 3.99Å; F239-F425 HydrophobicContact CG-CE2 4.37Å; L370-F425 HydrophobicContact CD2-CD1 3.73Å; L370-F425 HydrophobicContact CD2-CE1 3.43Å; L370-F425 VanDerWaalsContact CD2-CE1 3.43Å; L370-F425 HydrophobicContact CD2-CZ 4.44Å; F420-F425 AromaticContact CD1-CE1 3.73Å; F420-F425 HydrophobicContact CD1-CE1 3.73Å; F420-F425 HydrophobicContact CD1-CZ 4.33Å; F420-F425 HydrophobicContact CE1-CE1 4.28Å; F420-F425 HydrophobicContact CE1-CZ 4.44Å; D422-F425 HydrophobicContact CB-CB 3.95Å; D422-F425 PolarHBondContact O-N 3.28Å; D422-F425 VanDerWaalsContact O-N 3.11Å; D422-F425 PolarHBondContact OD1-N 3.33Å; F425-Y429 HydrophobicContact CZ-CD2 4.45Å; F425-Y429 WeakPolarHBondContact O-CB 3.39Å; F425-Y429 PolarHBondContact O-N 2.65Å
426T97Very high97Very high0 Ų015.9 Ų15.90%09%0.088CC..Hα-helixtrans-67.4-47.2178.954.10000111.8Y140 L370 F420 D422 H423 Y428 Y429 L430Y140-T426 HydrophobicContact CE2-CG2 4.03Å; Y140-T426 WeakPolarHBondContact OH-CB 3.34Å; Y140-T426 PolarHBondContact OH-OG1 3.07Å; L370-T426 HydrophobicContact CD1-CG2 4.08Å; L370-T426 HydrophobicContact CD2-CG2 4.02Å; F420-T426 WeakPolarHBondContact O-CG2 3.34Å; D422-T426 WeakPolarHBondContact O-CG2 3.38Å; D422-T426 PolarHBondContact O-N 3.09Å; D422-T426 PolarHBondContact O-OG1 2.88Å; H423-T426 PolarHBondContact O-OG1 3.41Å; H423-T426 VanDerWaalsContact O-OG1 3.12Å; T426-Y428 VanDerWaalsContact C-N 3.31Å; T426-Y428 PolarHBondContact O-N 2.9Å; T426-Y429 PolarHBondContact O-N 2.83Å; T426-L430 WeakPolarHBondContact O-CB 3.36Å; T426-L430 VanDerWaalsContact O-CG 3.27Å; T426-L430 WeakPolarHBondContact O-CG 3.31Å; T426-L430 PolarHBondContact O-N 2.84Å
427S95.1Very high97Very high6 Ų616.4 Ų16.44%0.0429%0.09CC..Hα-helixtrans-58.3-43.5177.1-67.20000111.4D209 H423 S431D209-S427 WeakPolarHBondContact O-CB 3.31Å; D209-S427 PolarHBondContact O-OG 2.94Å; H423-S427 VanDerWaalsContact O-CB 3.25Å; H423-S427 WeakPolarHBondContact O-CB 3.26Å; H423-S427 PolarHBondContact O-N 2.78Å; H423-S427 PolarHBondContact O-OG 2.95Å; S427-S431 WeakPolarHBondContact O-CB 3.19Å; S427-S431 PolarHBondContact O-N 2.83Å
428Y95.6Very high96.9Very high28 Ų2818.6 Ų18.611%0.1110%0.101CC..Hα-helixtrans-62.7-51.2176179.4-102.9000111.8L222 V231 N234 I235 L238 R424 T426 L430 S431 L432L222-Y428 HydrophobicContact CD1-CD2 4.1Å; L222-Y428 HydrophobicContact CD1-CE2 4.44Å; V231-Y428 WeakPolarHBondContact CA-OH 3.46Å; N234-Y428 HydrophobicContact CB-CD1 4.31Å; N234-Y428 HydrophobicContact CB-CE1 3.51Å; N234-Y428 HydrophobicContact CB-CE2 4.02Å; N234-Y428 WeakPolarHBondContact CB-OH 2.97Å; N234-Y428 PolarHBondContact ND2-OH 2.75Å; N234-Y428 VanDerWaalsContact ND2-OH 3.11Å; I235-Y428 HydrophobicContact CG1-CE1 4.13Å; L238-Y428 HydrophobicContact CD1-CD1 3.65Å; L238-Y428 HydrophobicContact CD1-CD2 4.18Å; L238-Y428 HydrophobicContact CD1-CG 3.42Å; L238-Y428 VanDerWaalsContact CD1-CG 3.42Å; R424-Y428 VanDerWaalsContact O-CB 3.26Å; R424-Y428 WeakPolarHBondContact O-CB 3.32Å; R424-Y428 PolarHBondContact O-N 2.98Å; T426-Y428 VanDerWaalsContact C-N 3.31Å; T426-Y428 PolarHBondContact O-N 2.9Å; Y428-L430 VanDerWaalsContact C-N 3.31Å; Y428-L430 PolarHBondContact O-N 3.13Å; Y428-S431 WeakPolarHBondContact O-CB 3.49Å; Y428-S431 PolarHBondContact O-N 3.28Å; Y428-S431 VanDerWaalsContact O-N 3.1Å; Y428-S431 PolarHBondContact O-OG 2.95Å; Y428-L432 HydrophobicContact CE1-CD2 4.06Å; Y428-L432 PolarHBondContact O-N 3.2Å
429Y97.3Very high96.7Very high0 Ų019.6 Ų19.60%011%0.107CC..Hα-helixtrans-61.4-41.7-178.3-159.5-78.5000111.1I235 L370 T371 F425 T426 S431 L432 R437 L447I235-Y429 HydrophobicContact CD1-CD2 4.11Å; I235-Y429 HydrophobicContact CD1-CE2 3.93Å; I235-Y429 HydrophobicContact CG1-CD2 4.31Å; L370-Y429 HydrophobicContact CD1-CD1 4.28Å; L370-Y429 HydrophobicContact CD1-CG 4.48Å; L370-Y429 HydrophobicContact CD2-CG 4.21Å; L370-Y429 HydrophobicContact CG-CD1 3.96Å; L370-Y429 HydrophobicContact CG-CG 4.1Å; T371-Y429 HydrophobicContact CG2-CD1 4.47Å; T371-Y429 HydrophobicContact CG2-CD2 4.42Å; T371-Y429 HydrophobicContact CG2-CE1 3.89Å; T371-Y429 HydrophobicContact CG2-CE2 3.83Å; F425-Y429 HydrophobicContact CZ-CD2 4.45Å; F425-Y429 WeakPolarHBondContact O-CB 3.39Å; F425-Y429 PolarHBondContact O-N 2.65Å; T426-Y429 PolarHBondContact O-N 2.83Å; Y429-S431 VanDerWaalsContact C-N 3.29Å; Y429-S431 PolarHBondContact O-N 3.44Å; Y429-L432 HydrophobicContact CD2-CD1 4.34Å; Y429-L432 HydrophobicContact CG-CD1 4.36Å; Y429-L432 WeakPolarHBondContact O-CB 3.43Å; Y429-L432 WeakPolarHBondContact O-CG 3.24Å; Y429-L432 PolarHBondContact O-N 2.89Å; Y429-R437 HydrophobicContact CD1-CG 4.17Å; Y429-R437 HydrophobicContact CE1-CB 4.23Å; Y429-R437 VanDerWaalsContact CE1-CD 3.49Å; Y429-R437 HydrophobicContact CE1-CG 3.64Å; Y429-R437 VanDerWaalsContact O-CD 3.3Å; Y429-R437 WeakPolarHBondContact O-CD 3.45Å; Y429-L447 HydrophobicContact CE2-CD2 4.33Å
430L96.6Very high96.5Very high13 Ų1323.4 Ų23.47%0.06812%0.124CC..Hα-helixtrans-69-24.2177.3-68.9172.8000113.6Y207 L370 L394 T426 Y428 L432Y207-L430 VanDerWaalsContact O-CD1 3.29Å; Y207-L430 WeakPolarHBondContact O-CD1 3.14Å; L370-L430 HydrophobicContact CD1-CD1 4.3Å; L370-L430 HydrophobicContact CD1-CD2 3.95Å; L370-L430 HydrophobicContact CD1-CG 3.75Å; L394-L430 HydrophobicContact CD1-CD1 3.78Å; L394-L430 HydrophobicContact CD1-CD2 4.04Å; L394-L430 HydrophobicContact CD1-CG 4.38Å; T426-L430 WeakPolarHBondContact O-CB 3.36Å; T426-L430 VanDerWaalsContact O-CG 3.27Å; T426-L430 WeakPolarHBondContact O-CG 3.31Å; T426-L430 PolarHBondContact O-N 2.84Å; Y428-L430 VanDerWaalsContact C-N 3.31Å; Y428-L430 PolarHBondContact O-N 3.13Å; L430-L432 VanDerWaalsContact C-N 3.27Å; L430-L432 PolarHBondContact O-N 2.66Å
431S94.7Very high96.2Very high57 Ų5730 Ų3040%0.39916%0.159SC..Hα-helixtrans-74.3-15.8174.579.40000113.8S427 Y428 Y429S427-S431 WeakPolarHBondContact O-CB 3.19Å; S427-S431 PolarHBondContact O-N 2.83Å; Y428-S431 WeakPolarHBondContact O-CB 3.49Å; Y428-S431 PolarHBondContact O-N 3.28Å; Y428-S431 VanDerWaalsContact O-N 3.1Å; Y428-S431 PolarHBondContact O-OG 2.95Å; Y429-S431 VanDerWaalsContact C-N 3.29Å; Y429-S431 PolarHBondContact O-N 3.44Å
432L96.3Very high95.9Very high4 Ų433.1 Ų33.12%0.02119%0.192CC..SBendtrans-65.7144.1179.4-60.6177.2000111.1F226 V231 I235 Y428 Y429 L430 A434 R437 L447F226-L432 HydrophobicContact CD1-CD2 3.69Å; F226-L432 HydrophobicContact CE1-CD2 3.84Å; V231-L432 HydrophobicContact CG1-CD1 3.84Å; V231-L432 HydrophobicContact CG1-CD2 3.86Å; V231-L432 HydrophobicContact CG2-CD2 3.91Å; I235-L432 HydrophobicContact CD1-CD1 4.48Å; Y428-L432 HydrophobicContact CE1-CD2 4.06Å; Y428-L432 PolarHBondContact O-N 3.2Å; Y429-L432 HydrophobicContact CD2-CD1 4.34Å; Y429-L432 HydrophobicContact CG-CD1 4.36Å; Y429-L432 WeakPolarHBondContact O-CB 3.43Å; Y429-L432 WeakPolarHBondContact O-CG 3.24Å; Y429-L432 PolarHBondContact O-N 2.89Å; L430-L432 VanDerWaalsContact C-N 3.27Å; L430-L432 PolarHBondContact O-N 2.66Å; L432-A434 PolarHBondContact O-N 3.47Å; L432-R437 HydrophobicContact CB-CG 4.24Å; L432-R437 PolarHBondContact O-NE 3.49Å; L432-L447 HydrophobicContact CD1-CD2 3.65Å
433P96.8Very high95.7Very high47 Ų4734 Ų3431%0.30520%0.197SC..  trans-46.6134.8168.1-26.832.4000111.4F226 E435 L436F226-P433 HydrophobicContact CB-CG 4.33Å; F226-P433 HydrophobicContact CD2-CG 4.14Å; F226-P433 HydrophobicContact CG-CG 4.1Å; P433-E435 WeakPolarHBondContact CB-OE2 3.34Å; P433-E435 PolarHBondContact O-N 3.38Å; P433-E435 VanDerWaalsContact O-N 3.16Å; P433-L436 HydrophobicContact CB-CD1 4.46Å; P433-L436 HydrophobicContact CB-CG 4.3Å; P433-L436 HydrophobicContact CG-CD1 4.24Å; P433-L436 WeakPolarHBondContact O-CB 3.34Å; P433-L436 PolarHBondContact O-N 3.2Å
434A97.3Very high95.8Very high14 Ų1433.8 Ų33.812%0.11620%0.196CC..Hα-helixtrans-59.4-33-171.700000112.1P383 A387 L432 L436 R437 I438P383-A434 HydrophobicContact CB-CB 3.61Å; A387-A434 HydrophobicContact CB-CB 4.32Å; L432-A434 PolarHBondContact O-N 3.47Å; A434-L436 PolarHBondContact O-N 3.21Å; A434-R437 PolarHBondContact O-N 2.94Å; A434-I438 PolarHBondContact O-N 2.78Å
435E97.4Very high95.9Very high96 Ų9633.1 Ų33.145%0.44919%0.193SC..Hα-helixtrans-67.8-18179.4-5187.9160.400113.8P383 P433 K440P383-E435 HydrophobicContact CB-CG 4.27Å; P383-E435 HydrophobicContact CG-CG 4.05Å; P433-E435 WeakPolarHBondContact CB-OE2 3.34Å; P433-E435 PolarHBondContact O-N 3.38Å; P433-E435 VanDerWaalsContact O-N 3.16Å; E435-K440 VanDerWaalsContact O-CE 3.29Å; E435-K440 WeakPolarHBondContact O-CE 3.24Å; E435-K440 PolarHBondContact O-NZ 3.09Å
436L97.1Very high96Very high40 Ų4035.2 Ų35.221%0.20920%0.202CC..Hα-helixtrans-82-22.8172.1-63.5-175.2000112F226 V231 P433 A434 L447F226-L436 HydrophobicContact CB-CD1 4.44Å; V231-L436 HydrophobicContact CG2-CD1 4.45Å; P433-L436 HydrophobicContact CB-CD1 4.46Å; P433-L436 HydrophobicContact CB-CG 4.3Å; P433-L436 HydrophobicContact CG-CD1 4.24Å; P433-L436 WeakPolarHBondContact O-CB 3.34Å; P433-L436 PolarHBondContact O-N 3.2Å; A434-L436 PolarHBondContact O-N 3.21Å; L436-L447 HydrophobicContact CB-CD2 4.37Å
437R97.4Very high96Very high12 Ų1235.6 Ų35.65%0.04520%0.203CC..Hα-helixtrans-92.9-24.3-173.8-64.4-168.8-81.3139.1-5114.2Q372 A387 Y429 L432 A434Q372-R437 PolarHBondContact OE1-O 2.83Å; A387-R437 VanDerWaalsContact CB-NH2 3.26Å; Y429-R437 HydrophobicContact CD1-CG 4.17Å; Y429-R437 HydrophobicContact CE1-CB 4.23Å; Y429-R437 VanDerWaalsContact CE1-CD 3.49Å; Y429-R437 HydrophobicContact CE1-CG 3.64Å; Y429-R437 VanDerWaalsContact O-CD 3.3Å; Y429-R437 WeakPolarHBondContact O-CD 3.45Å; L432-R437 HydrophobicContact CB-CG 4.24Å; L432-R437 PolarHBondContact O-NE 3.49Å; A434-R437 PolarHBondContact O-N 2.94Å
438I97.2Very high96.2Very high46 Ų4635.3 Ų35.324%0.23620%0.201CC..SBendtrans-61.1150.8-179.760.8173.9000112.4P383 A386 A434P383-I438 HydrophobicContact CB-CG2 3.86Å; P383-I438 HydrophobicContact CG-CD1 4.31Å; P383-I438 HydrophobicContact CG-CG2 4.19Å; A386-I438 HydrophobicContact CB-CG2 4.35Å; A434-I438 PolarHBondContact O-N 2.78Å
439P95.6Very high96.3Very high22 Ų2234 Ų3414%0.14320%0.196CC..  trans-52.3140.3167.9-25.234.2000112F377 H378 I443F377-P439 HydrophobicContact CB-CG 4.24Å; H378-P439 VanDerWaalsContact CE1-CB 3.46Å; H378-P439 WeakPolarHBondContact CE1-CB 3.44Å; H378-P439 WeakPolarHBondContact ND1-CB 3.49Å; P439-I443 WeakPolarHBondContact CA-O 3.26Å
440K94.3Very high96.4Very high81 Ų8135.4 Ų35.435%0.35220%0.203SC..BIsolated β-bridgetrans-132.9151.1177.6-73.8-175.1-178.5173.60109.9E435 G442 I443 Y446E435-K440 VanDerWaalsContact O-CE 3.29Å; E435-K440 WeakPolarHBondContact O-CE 3.24Å; E435-K440 PolarHBondContact O-NZ 3.09Å; K440-G442 PolarHBondContact O-N 3.21Å; K440-G442 VanDerWaalsContact O-N 3.15Å; K440-I443 PolarHBondContact N-O 2.76Å; K440-I443 VanDerWaalsContact O-CG2 3.29Å; K440-I443 WeakPolarHBondContact O-CG2 3.4Å; K440-I443 PolarHBondContact O-N 3.34Å; K440-I443 VanDerWaalsContact O-O 3.13Å; K440-Y446 HydrophobicContact CB-CD1 3.93Å; K440-Y446 HydrophobicContact CB-CD2 4.21Å; K440-Y446 HydrophobicContact CB-CE1 4.41Å; K440-Y446 HydrophobicContact CB-CG 3.82Å; K440-Y446 HydrophobicContact CD-CD1 4.35Å
441N92.9Very high96.4Very high138 Ų13834.8 Ų34.874%0.73820%0.199SC*.THydrogen-bonded Turntrans53.135.4178.5-58.1-22.2000113.8I443 Y446N441-I443 PolarHBondContact O-N 3.16Å; N441-Y446 HydrophobicContact CB-CE2 4.33Å; N441-Y446 PolarHBondContact ND2-OH 2.98Å
442G90.2Very high96.6Very high69 Ų6932.2 Ų32.271%0.71118%0.181SC*.THydrogen-bonded Turntrans7210.4179.500000115.1K440K440-G442 PolarHBondContact O-N 3.21Å; K440-G442 VanDerWaalsContact O-N 3.15Å
443I94.8Very high96.6Very high20 Ų2034.9 Ų34.910%0.10319%0.193CC..BIsolated β-bridgetrans-126.3133.6178.9-169.8153.6000111.9P439 K440 N441 Y446 W464P439-I443 WeakPolarHBondContact CA-O 3.26Å; K440-I443 PolarHBondContact N-O 2.76Å; K440-I443 VanDerWaalsContact O-CG2 3.29Å; K440-I443 WeakPolarHBondContact O-CG2 3.4Å; K440-I443 PolarHBondContact O-N 3.34Å; K440-I443 VanDerWaalsContact O-O 3.13Å; N441-I443 PolarHBondContact O-N 3.16Å; I443-Y446 HydrophobicContact CG2-CD2 3.55Å; I443-Y446 HydrophobicContact CG2-CE2 4.32Å; I443-Y446 HydrophobicContact CG2-CG 4.5Å; I443-W464 HydrophobicContact CD1-CE3 4.02Å; I443-W464 VanDerWaalsContact CD1-O 3.26Å; I443-W464 WeakPolarHBondContact CD1-O 3.44Å; I443-W464 HydrophobicContact CG2-CE3 4.33Å; I443-W464 HydrophobicContact CG2-CZ3 4.11Å
444E96.6Very high96.4Very high2 Ų238.5 Ų38.51%0.00921%0.21CC..THydrogen-bonded Turntrans-71.8158.3174.273.7-61.2151.400112G373 H378 Y446 R449 K467G373-E444 WeakPolarHBondContact O-CG 3.28Å; H378-E444 IonicContact NE2-OE2 3.93Å; E444-Y446 PolarHBondContact O-N 3.15Å; E444-Y446 VanDerWaalsContact O-N 3.13Å; E444-R449 PolarHBondContact O-NE 3.18Å; E444-R449 IonicContact OE1-CZ 2.69Å; E444-R449 IonicContact OE1-NH2 3.5Å; E444-R449 PolarHBondContact OE1-NH2 2.87Å; E444-K467 HydrophobicContact CG-CB 3.89Å; E444-K467 WeakPolarHBondContact OE1-CB 3.47Å; E444-K467 PolarHBondContact OE1-N 2.84Å
445K97.8Very high96.2Very high1 Ų140 Ų400%0.00422%0.22CC..THydrogen-bonded Turntrans55.329.5-179.6-47.5-179.1179.2166.60113.5L261 D262 D368 T371 G373 L447 L448 R449L261-K445 HydrophobicContact CD2-CB 4.02Å; L261-K445 HydrophobicContact CD2-CD 3.86Å; D262-K445 IonicContact OD1-NZ 2.95Å; D262-K445 PolarHBondContact OD1-NZ 2.75Å; D262-K445 IonicContact OD2-NZ 3.95Å; D262-K445 PolarHBondContact OD2-NZ 3.01Å; D368-K445 VanDerWaalsContact CG-NZ 3.28Å; D368-K445 WeakPolarHBondContact OD1-CE 3.21Å; D368-K445 IonicContact OD1-NZ 3.69Å; D368-K445 PolarHBondContact OD1-NZ 3.12Å; D368-K445 IonicContact OD2-NZ 3.39Å; T371-K445 WeakPolarHBondContact OG1-CD 3.08Å; T371-K445 VanDerWaalsContact OG1-CG 3.28Å; T371-K445 WeakPolarHBondContact OG1-CG 3.31Å; G373-K445 VanDerWaalsContact CA-CE 3.4Å; K445-L447 VanDerWaalsContact C-N 3.3Å; K445-L447 PolarHBondContact O-N 3.47Å; K445-L448 HydrophobicContact CB-CB 4.19Å; K445-L448 HydrophobicContact CD-CD2 4.4Å; K445-L448 WeakPolarHBondContact O-CB 3.48Å; K445-L448 PolarHBondContact O-N 2.9Å; K445-R449 WeakPolarHBondContact O-CG 3.28Å; K445-R449 PolarHBondContact O-N 3.38Å
446Y97.8Very high96.1Very high44 Ų4441.4 Ų41.417%0.17323%0.231CC..Hα-helixtrans-53.1-47-173.8-174.3-95.1000112.1K440 N441 I443 E444 L448 R449 Q450 W464K440-Y446 HydrophobicContact CB-CD1 3.93Å; K440-Y446 HydrophobicContact CB-CD2 4.21Å; K440-Y446 HydrophobicContact CB-CE1 4.41Å; K440-Y446 HydrophobicContact CB-CG 3.82Å; K440-Y446 HydrophobicContact CD-CD1 4.35Å; N441-Y446 HydrophobicContact CB-CE2 4.33Å; N441-Y446 PolarHBondContact ND2-OH 2.98Å; I443-Y446 HydrophobicContact CG2-CD2 3.55Å; I443-Y446 HydrophobicContact CG2-CE2 4.32Å; I443-Y446 HydrophobicContact CG2-CG 4.5Å; E444-Y446 PolarHBondContact O-N 3.15Å; E444-Y446 VanDerWaalsContact O-N 3.13Å; Y446-L448 PolarHBondContact O-N 3.21Å; Y446-R449 PolarHBondContact O-N 3.47Å; Y446-Q450 HydrophobicContact CD1-CG 4.06Å; Y446-Q450 HydrophobicContact CE1-CG 3.71Å; Y446-Q450 WeakPolarHBondContact O-CG 3.27Å; Y446-Q450 PolarHBondContact O-N 2.76Å; Y446-Q450 PolarHBondContact OH-NE2 3.32Å; Y446-W464 HydrophobicContact CD2-CH2 4.06Å; Y446-W464 AromaticContact CD2-CZ3 3.68Å; Y446-W464 HydrophobicContact CD2-CZ3 3.68Å; Y446-W464 AromaticContact CE2-CH2 3.77Å; Y446-W464 HydrophobicContact CE2-CH2 3.77Å; Y446-W464 AromaticContact CE2-CZ3 3.7Å; Y446-W464 HydrophobicContact CE2-CZ3 3.7Å
447L98.4Very high96Very high7 Ų740.8 Ų40.84%0.03723%0.227CC..Hα-helixtrans-61.5-41.4178.2-179.462.4000112.8L228 V231 I235 Y429 L432 L436 K445 S451L228-L447 HydrophobicContact CD1-CD1 3.83Å; V231-L447 HydrophobicContact CG1-CD1 4.03Å; V231-L447 HydrophobicContact CG1-CD2 3.95Å; V231-L447 HydrophobicContact CG1-CG 4.44Å; I235-L447 HydrophobicContact CD1-CD1 4.37Å; I235-L447 HydrophobicContact CD1-CD2 3.84Å; I235-L447 HydrophobicContact CD1-CG 3.77Å; Y429-L447 HydrophobicContact CE2-CD2 4.33Å; L432-L447 HydrophobicContact CD1-CD2 3.65Å; L436-L447 HydrophobicContact CB-CD2 4.37Å; K445-L447 VanDerWaalsContact C-N 3.3Å; K445-L447 PolarHBondContact O-N 3.47Å; L447-S451 WeakPolarHBondContact O-CB 3.23Å; L447-S451 PolarHBondContact O-N 3.26Å; L447-S451 PolarHBondContact O-OG 2.79Å
448L98.6Very high95.9Very high0 Ų040.7 Ų40.70%023%0.228CC..Hα-helixtrans-63-45.2176.4-176.267.1000110.6I235 L261 L265 T371 F420 K445 Y446 S451 F452I235-L448 HydrophobicContact CG2-CD1 4.13Å; L261-L448 HydrophobicContact CD2-CD2 3.99Å; L261-L448 HydrophobicContact CD2-CG 4.49Å; L265-L448 HydrophobicContact CD1-CD1 4.34Å; L265-L448 HydrophobicContact CD1-CD2 4.07Å; L265-L448 HydrophobicContact CD1-CG 4Å; T371-L448 HydrophobicContact CG2-CD2 4.35Å; F420-L448 HydrophobicContact CE1-CD1 4.25Å; F420-L448 HydrophobicContact CE1-CD2 3.89Å; F420-L448 HydrophobicContact CZ-CD2 4.18Å; K445-L448 HydrophobicContact CB-CB 4.19Å; K445-L448 HydrophobicContact CD-CD2 4.4Å; K445-L448 WeakPolarHBondContact O-CB 3.48Å; K445-L448 PolarHBondContact O-N 2.9Å; Y446-L448 PolarHBondContact O-N 3.21Å; L448-S451 WeakPolarHBondContact O-CB 3.46Å; L448-S451 PolarHBondContact O-N 2.91Å; L448-F452 HydrophobicContact CD1-CD2 4.3Å; L448-F452 HydrophobicContact CD1-CE2 3.81Å; L448-F452 WeakPolarHBondContact O-CD2 3.39Å
449R98.4Very high95.9Very high2 Ų239.7 Ų39.71%0.00822%0.224CC..Hα-helixtrans-60.9-48.8178.3-63.1172.1-172.1-87.26.3111.5L261 E444 K445 Y446 S451 F452 E453 L463 W464 R465L261-R449 HydrophobicContact CD1-CG 4.18Å; L261-R449 HydrophobicContact CD2-CG 3.54Å; E444-R449 PolarHBondContact O-NE 3.18Å; E444-R449 IonicContact OE1-CZ 2.69Å; E444-R449 IonicContact OE1-NH2 3.5Å; E444-R449 PolarHBondContact OE1-NH2 2.87Å; K445-R449 WeakPolarHBondContact O-CG 3.28Å; K445-R449 PolarHBondContact O-N 3.38Å; Y446-R449 PolarHBondContact O-N 3.47Å; R449-S451 VanDerWaalsContact C-N 3.26Å; R449-S451 PolarHBondContact O-N 3.03Å; R449-F452 PolarHBondContact O-N 3.43Å; R449-F452 VanDerWaalsContact O-N 3.14Å; R449-E453 PolarHBondContact O-N 3.14Å; R449-L463 HydrophobicContact CB-CD1 4.39Å; R449-L463 WeakPolarHBondContact CD-O 3.3Å; R449-L463 VanDerWaalsContact CG-O 3.29Å; R449-L463 WeakPolarHBondContact CG-O 3.23Å; R449-L463 PolarHBondContact NH1-O 3.48Å; R449-W464 HydrophobicContact CB-CD2 4.43Å; R449-W464 HydrophobicContact CB-CE3 4.07Å; R449-W464 HydrophobicContact CB-CH2 3.86Å; R449-W464 HydrophobicContact CB-CZ2 4.22Å; R449-W464 HydrophobicContact CB-CZ3 3.78Å; R449-W464 HydrophobicContact CG-CE3 4.45Å; R449-W464 HydrophobicContact CG-CZ3 4.45Å; R449-R465 VanDerWaalsContact CZ-O 3.25Å; R449-R465 PolarHBondContact NH1-O 2.99Å; R449-R465 PolarHBondContact NH2-O 3.33Å
450Q97.8Very high96Very high28 Ų2846.5 Ų46.513%0.13125%0.252CS..Hα-helixtrans-59.1-37.7175.7-72.1-162.5-58.100112.4K232 Y446 F452 E453 W464K232-Q450 HydrophobicContact CD-CB 4.33Å; K232-Q450 VanDerWaalsContact CE-O 3.24Å; K232-Q450 WeakPolarHBondContact CE-O 3.43Å; Y446-Q450 HydrophobicContact CD1-CG 4.06Å; Y446-Q450 HydrophobicContact CE1-CG 3.71Å; Y446-Q450 WeakPolarHBondContact O-CG 3.27Å; Y446-Q450 PolarHBondContact O-N 2.76Å; Y446-Q450 PolarHBondContact OH-NE2 3.32Å; Q450-F452 PolarHBondContact O-N 3.18Å; Q450-F452 VanDerWaalsContact O-N 3.09Å; Q450-E453 VanDerWaalsContact O-CG 3.31Å; Q450-E453 WeakPolarHBondContact O-CG 3.45Å; Q450-E453 PolarHBondContact O-N 3.35Å; Q450-W464 HydrophobicContact CG-CH2 3.87Å; Q450-W464 HydrophobicContact CG-CZ2 4.38Å
451S98.2Very high96Very high0 Ų048.1 Ų48.10%026%0.26CS..Hα-helixtrans-60.1-23.8179.9-600000112.9I235 R236 L447 L448 R449I235-S451 WeakPolarHBondContact CD1-OG 3.24Å; R236-S451 WeakPolarHBondContact CD-O 3.38Å; R236-S451 WeakPolarHBondContact CG-O 3.26Å; R236-S451 PolarHBondContact NH1-O 2.92Å; L447-S451 WeakPolarHBondContact O-CB 3.23Å; L447-S451 PolarHBondContact O-N 3.26Å; L447-S451 PolarHBondContact O-OG 2.79Å; L448-S451 WeakPolarHBondContact O-CB 3.46Å; L448-S451 PolarHBondContact O-N 2.91Å; R449-S451 VanDerWaalsContact C-N 3.26Å; R449-S451 PolarHBondContact O-N 3.03Å
452F98.1Very high96.2Very high3 Ų341.8 Ų41.81%0.01323%0.226CC..Hα-helixtrans-1144.9-179.9-66.4-78.4000114.4I235 R236 F239 L265 V269 L448 R449 Q450 D454 S455 L457 L463I235-F452 HydrophobicContact CG2-CE2 4.24Å; R236-F452 HydrophobicContact CB-CE1 4.43Å; R236-F452 HydrophobicContact CG-CD1 4.07Å; R236-F452 HydrophobicContact CG-CE1 3.85Å; R236-F452 HydrophobicContact CG-CZ 4.27Å; F239-F452 HydrophobicContact CB-CZ 4.14Å; F239-F452 HydrophobicContact CD1-CE1 4.39Å; F239-F452 HydrophobicContact CD1-CE2 4.48Å; F239-F452 AromaticContact CD1-CZ 3.7Å; F239-F452 HydrophobicContact CD1-CZ 3.7Å; F239-F452 HydrophobicContact CE1-CZ 4.47Å; F239-F452 HydrophobicContact CG-CZ 4.17Å; L265-F452 HydrophobicContact CD1-CD2 3.78Å; L265-F452 HydrophobicContact CD1-CE2 4.02Å; L265-F452 HydrophobicContact CD2-CB 3.8Å; L265-F452 HydrophobicContact CD2-CD1 4.08Å; L265-F452 HydrophobicContact CD2-CD2 3.69Å; L265-F452 HydrophobicContact CD2-CE2 4.28Å; L265-F452 HydrophobicContact CD2-CG 3.58Å; L265-F452 HydrophobicContact CG-CD2 4.4Å; V269-F452 HydrophobicContact CG2-CE1 4.44Å; L448-F452 HydrophobicContact CD1-CD2 4.3Å; L448-F452 HydrophobicContact CD1-CE2 3.81Å; L448-F452 WeakPolarHBondContact O-CD2 3.39Å; R449-F452 PolarHBondContact O-N 3.43Å; R449-F452 VanDerWaalsContact O-N 3.14Å; Q450-F452 PolarHBondContact O-N 3.18Å; Q450-F452 VanDerWaalsContact O-N 3.09Å; F452-D454 PolarHBondContact O-N 3.11Å; F452-S455 WeakPolarHBondContact O-CB 3.2Å; F452-S455 PolarHBondContact O-N 2.92Å; F452-S455 PolarHBondContact O-OG 2.97Å; F452-L457 HydrophobicContact CD1-CD1 3.87Å; F452-L457 HydrophobicContact CE1-CD1 4.32Å; F452-L463 HydrophobicContact CB-CD1 4.31Å
453E96.1Very high96.5Very high60 Ų6038.8 Ų38.828%0.2819%0.194SC..G310 helixtrans-61.9-38.1-173.376.9-165.2156.800114.4K232 R449 Q450 S455 L463K232-E453 IonicContact NZ-OE1 3.44Å; K232-E453 PolarHBondContact NZ-OE1 3.11Å; R449-E453 PolarHBondContact O-N 3.14Å; Q450-E453 VanDerWaalsContact O-CG 3.31Å; Q450-E453 WeakPolarHBondContact O-CG 3.45Å; Q450-E453 PolarHBondContact O-N 3.35Å; E453-S455 VanDerWaalsContact C-N 3.33Å; E453-L463 VanDerWaalsContact CA-CD2 3.49Å; E453-L463 HydrophobicContact CB-CD2 3.97Å
454D93.4Very high96.6Very high124 Ų12441.7 Ų41.766%0.66320%0.204SC*.G310 helixtrans-89.3-0.3-177.7-57.4-51.5000113.1K232 F452K232-D454 IonicContact NZ-OD2 3.52Å; F452-D454 PolarHBondContact O-N 3.11Å
455S92.7Very high96.5Very high45 Ų4544.4 Ų44.432%0.31521%0.214SC..G310 helixtrans-82.5-17-173.5720000114.1F452 E453 L457F452-S455 WeakPolarHBondContact O-CB 3.2Å; F452-S455 PolarHBondContact O-N 2.92Å; F452-S455 PolarHBondContact O-OG 2.97Å; E453-S455 VanDerWaalsContact C-N 3.33Å; S455-L457 PolarHBondContact O-N 3.08Å; S455-L457 WeakPolarHBondContact OG-CB 3.44Å; S455-L457 WeakPolarHBondContact OG-CD1 3.26Å; S455-L457 VanDerWaalsContact OG-CG 3.28Å; S455-L457 WeakPolarHBondContact OG-CG 3.37Å; S455-L457 PolarHBondContact OG-N 3.07Å
456N94Very high96.1Very high126 Ų12648.5 Ų48.567%0.67424%0.241SC*.  trans5219.8-168.7-164.539.8000114.2H305 L458H305-N456 PolarHBondContact NE2-O 2.89Å; N456-L458 VanDerWaalsContact C-N 3.26Å; N456-L458 PolarHBondContact O-N 3.2Å
457L95.1Very high95.6Very high27 Ų2748.3 Ų48.314%0.14124%0.241CC..SBendtrans-67-29.5179.5-75.4173000112.4A268 V269 K272 H305 F452 S455A268-L457 HydrophobicContact CB-CB 4.05Å; A268-L457 HydrophobicContact CB-CD2 4.3Å; V269-L457 HydrophobicContact CG2-CD1 3.85Å; K272-L457 HydrophobicContact CD-CD2 4.45Å; H305-L457 PolarHBondContact CD2-O 3.07Å; F452-L457 HydrophobicContact CD1-CD1 3.87Å; F452-L457 HydrophobicContact CE1-CD1 4.32Å; S455-L457 PolarHBondContact O-N 3.08Å; S455-L457 WeakPolarHBondContact OG-CB 3.44Å; S455-L457 WeakPolarHBondContact OG-CD1 3.26Å; S455-L457 VanDerWaalsContact OG-CG 3.28Å; S455-L457 WeakPolarHBondContact OG-CG 3.37Å; S455-L457 PolarHBondContact OG-N 3.07Å
458L97Very high94.8Very high10 Ų1050.3 Ų50.35%0.05225%0.25CC..SBendtrans-132.1152.2-178-62.8-178.8000111.3L261 L265 A268 V302 N456 K460 I462 L463L261-L458 HydrophobicContact CD1-CD1 4.46Å; L265-L458 HydrophobicContact CD2-CD1 3.71Å; L265-L458 HydrophobicContact CD2-CG 4.36Å; L265-L458 HydrophobicContact CG-CD1 3.91Å; A268-L458 HydrophobicContact CB-CD2 3.95Å; V302-L458 HydrophobicContact CG1-CD2 3.95Å; N456-L458 VanDerWaalsContact C-N 3.26Å; N456-L458 PolarHBondContact O-N 3.2Å; L458-K460 PolarHBondContact O-N 2.74Å; L458-I462 HydrophobicContact CD1-CG2 4.42Å; L458-L463 HydrophobicContact CB-CB 4.46Å; L458-L463 HydrophobicContact CD1-CD1 4.49Å
459P97.1Very high93.8Very high24 Ų2451.7 Ų51.716%0.15626%0.261CS..  trans-56.6137.9164.6-21.332.8000110.5H305 E461 I462 L463H305-P459 HydrophobicContact CB-CG 3.79Å; P459-E461 HydrophobicContact CB-CG 3.98Å; P459-E461 PolarHBondContact O-N 2.85Å; P459-E461 VanDerWaalsContact O-N 3.16Å; P459-I462 HydrophobicContact CB-CG1 4.2Å; P459-I462 HydrophobicContact CG-CG1 4.24Å; P459-I462 PolarHBondContact O-N 3.49Å; P459-L463 PolarHBondContact O-N 2.74Å
460K96.2Very high93Very high166 Ų16654 Ų5472%0.72227%0.271SS*.Hα-helixtrans-54.8-37.4-178.8-71.3-170.3175.3-173.10113L458 I462 L463 W464L458-K460 PolarHBondContact O-N 2.74Å; K460-I462 VanDerWaalsContact C-N 3.27Å; K460-I462 PolarHBondContact O-N 2.92Å; K460-L463 PolarHBondContact O-N 3.37Å; K460-W464 PolarHBondContact O-N 2.82Å
461E95.7Very high91.9Very high115 Ų11553.5 Ų53.554%0.53727%0.271SS..Hα-helixtrans-64.4-27.8177.259.1-177.6-131.400113.8K301 P459 R465K301-E461 VanDerWaalsContact CD-OE1 3.25Å; K301-E461 WeakPolarHBondContact CD-OE1 3.45Å; K301-E461 WeakPolarHBondContact CE-OE1 3.43Å; K301-E461 IonicContact NZ-OE1 3.01Å; K301-E461 PolarHBondContact NZ-OE1 2.78Å; P459-E461 HydrophobicContact CB-CG 3.98Å; P459-E461 PolarHBondContact O-N 2.85Å; P459-E461 VanDerWaalsContact O-N 3.16Å; E461-R465 WeakPolarHBondContact O-CB 3.3Å; E461-R465 PolarHBondContact O-N 2.96Å
462I96.4Very high90.9Very high4 Ų453.7 Ų53.72%0.02127%0.272CS..Hα-helixtrans-82.7-45.1172.9-61.2-64.1000109.8A298 V302 L458 P459 K460 W464 R465A298-I462 HydrophobicContact CB-CD1 4.17Å; V302-I462 HydrophobicContact CG2-CB 4.22Å; V302-I462 HydrophobicContact CG2-CD1 4.1Å; V302-I462 HydrophobicContact CG2-CG1 3.74Å; V302-I462 HydrophobicContact CG2-CG2 3.71Å; L458-I462 HydrophobicContact CD1-CG2 4.42Å; P459-I462 HydrophobicContact CB-CG1 4.2Å; P459-I462 HydrophobicContact CG-CG1 4.24Å; P459-I462 PolarHBondContact O-N 3.49Å; K460-I462 VanDerWaalsContact C-N 3.27Å; K460-I462 PolarHBondContact O-N 2.92Å; I462-W464 PolarHBondContact O-N 2.75Å; I462-W464 VanDerWaalsContact O-N 3.14Å; I462-R465 WeakPolarHBondContact O-CB 3.36Å; I462-R465 PolarHBondContact O-N 3.04Å; I462-R465 VanDerWaalsContact O-N 3.09Å
463L97.4Very high89.8Confident6 Ų653.5 Ų53.53%0.03127%0.271CS..Hα-helixtrans-57.6-30179.9-177.867000112.6L261 R449 F452 E453 L458 P459 K460L261-L463 HydrophobicContact CD1-CD1 3.79Å; R449-L463 HydrophobicContact CB-CD1 4.39Å; R449-L463 WeakPolarHBondContact CD-O 3.3Å; R449-L463 VanDerWaalsContact CG-O 3.29Å; R449-L463 WeakPolarHBondContact CG-O 3.23Å; R449-L463 PolarHBondContact NH1-O 3.48Å; F452-L463 HydrophobicContact CB-CD1 4.31Å; E453-L463 VanDerWaalsContact CA-CD2 3.49Å; E453-L463 HydrophobicContact CB-CD2 3.97Å; L458-L463 HydrophobicContact CB-CB 4.46Å; L458-L463 HydrophobicContact CD1-CD1 4.49Å; P459-L463 PolarHBondContact O-N 2.74Å; K460-L463 PolarHBondContact O-N 3.37Å
464W96.7Very high89Confident81 Ų8150.7 Ų50.731%0.30726%0.258SS..THydrogen-bonded Turntrans-112.814.1178.7-64.1103.1000113.7I443 Y446 R449 Q450 K460 I462I443-W464 HydrophobicContact CD1-CE3 4.02Å; I443-W464 VanDerWaalsContact CD1-O 3.26Å; I443-W464 WeakPolarHBondContact CD1-O 3.44Å; I443-W464 HydrophobicContact CG2-CE3 4.33Å; I443-W464 HydrophobicContact CG2-CZ3 4.11Å; Y446-W464 HydrophobicContact CD2-CH2 4.06Å; Y446-W464 AromaticContact CD2-CZ3 3.68Å; Y446-W464 HydrophobicContact CD2-CZ3 3.68Å; Y446-W464 AromaticContact CE2-CH2 3.77Å; Y446-W464 HydrophobicContact CE2-CH2 3.77Å; Y446-W464 AromaticContact CE2-CZ3 3.7Å; Y446-W464 HydrophobicContact CE2-CZ3 3.7Å; R449-W464 HydrophobicContact CB-CD2 4.43Å; R449-W464 HydrophobicContact CB-CE3 4.07Å; R449-W464 HydrophobicContact CB-CH2 3.86Å; R449-W464 HydrophobicContact CB-CZ2 4.22Å; R449-W464 HydrophobicContact CB-CZ3 3.78Å; R449-W464 HydrophobicContact CG-CE3 4.45Å; R449-W464 HydrophobicContact CG-CZ3 4.45Å; Q450-W464 HydrophobicContact CG-CH2 3.87Å; Q450-W464 HydrophobicContact CG-CZ2 4.38Å; K460-W464 PolarHBondContact O-N 2.82Å; I462-W464 PolarHBondContact O-N 2.75Å; I462-W464 VanDerWaalsContact O-N 3.14Å
465R93Very high88.4Confident60 Ų6045.4 Ų45.423%0.22623%0.23CC..PPolyproline II helixtrans-67.1129172.9-176.4178.6170.5140.1-13.7110.2R449 E461 I462 E468R449-R465 VanDerWaalsContact CZ-O 3.25Å; R449-R465 PolarHBondContact NH1-O 2.99Å; R449-R465 PolarHBondContact NH2-O 3.33Å; E461-R465 WeakPolarHBondContact O-CB 3.3Å; E461-R465 PolarHBondContact O-N 2.96Å; I462-R465 WeakPolarHBondContact O-CB 3.36Å; I462-R465 PolarHBondContact O-N 3.04Å; I462-R465 VanDerWaalsContact O-N 3.09Å; R465-E468 IonicContact CZ-OE2 3.74Å; R465-E468 IonicContact NH2-OE2 2.69Å; R465-E468 PolarHBondContact NH2-OE2 2.9Å
466P91.1Very high87.7Confident87 Ų8744.5 Ų44.557%0.56522%0.224SC*.PPolyproline II helixtrans-59154.5173.4-2434.2000113.1E468P466-E468 PolarHBondContact O-N 3.19Å
467K86.1Confident86.7Confident40 Ų4044.6 Ų44.617%0.17423%0.228CC..PPolyproline II helixtrans-62132.6-179.6-179.162.2168.275.30111.4D368 I375 E444 Y555D368-K467 WeakPolarHBondContact OD1-CE 3.41Å; D368-K467 WeakPolarHBondContact OD2-CE 3.26Å; D368-K467 IonicContact OD2-NZ 2.84Å; I375-K467 HydrophobicContact CD1-CB 4.1Å; E444-K467 HydrophobicContact CG-CB 3.89Å; E444-K467 WeakPolarHBondContact OE1-CB 3.47Å; E444-K467 PolarHBondContact OE1-N 2.84Å; K467-Y555 PolarHBondContact O-OH 3.5Å
468E81.3Confident85.7Confident49 Ų4953.2 Ų53.223%0.22927%0.265CS..  trans-120.7132.1167.8-165.7166.8-174.700109.1R465 P466 D472 G473R465-E468 IonicContact CZ-OE2 3.74Å; R465-E468 IonicContact NH2-OE2 2.69Å; R465-E468 PolarHBondContact NH2-OE2 2.9Å; P466-E468 PolarHBondContact O-N 3.19Å; E468-D472 HydrophobicContact CG-CB 4.43Å; E468-G473 WeakPolarHBondContact OE1-CA 3.41Å
469A78.7Confident84.9Confident29 Ų2956.4 Ų56.424%0.2428%0.278CS..  trans-70.9146.2177.600000110.7S471 D472 G473A469-S471 PolarHBondContact O-N 3Å; A469-D472 HydrophobicContact CB-CB 4.31Å; A469-D472 CarbonylContact O-C 3.55Å; A469-D472 WeakPolarHBondContact O-CA 3.44Å; A469-D472 WeakPolarHBondContact O-CB 2.97Å; A469-D472 PolarHBondContact O-N 3Å; A469-G473 PolarHBondContact O-N 2.9Å
470F80.8Confident84.3Confident51 Ų5155.7 Ų55.722%0.22427%0.274CS..Hα-helixtrans-59.6-46.6-172.1-175.8-113.9000113.1I288 A341 M345 D472 G473 I474I288-F470 HydrophobicContact CG2-CE2 4.47Å; I288-F470 HydrophobicContact CG2-CZ 3.86Å; A341-F470 HydrophobicContact CB-CD1 4.03Å; A341-F470 WeakPolarHBondContact O-CD1 3.46Å; A341-F470 VanDerWaalsContact O-CE1 3.23Å; A341-F470 WeakPolarHBondContact O-CE1 3.37Å; M345-F470 HydrophobicContact CB-CE1 4.4Å; F470-D472 PolarHBondContact O-N 2.92Å; F470-D472 VanDerWaalsContact O-N 3.13Å; F470-G473 PolarHBondContact O-N 2.9Å; F470-I474 HydrophobicContact CD2-CG2 4.42Å; F470-I474 HydrophobicContact CE2-CG2 4.09Å; F470-I474 HydrophobicContact CZ-CG2 4.2Å; F470-I474 WeakPolarHBondContact O-CG2 3.41Å; F470-I474 PolarHBondContact O-N 3.25Å
471S74.6Confident83.8Confident16 Ų1647.8 Ų47.811%0.11224%0.24CC..Hα-helixtrans-62.7-21.2176.258.10000113.5A469 I474A469-S471 PolarHBondContact O-N 3Å; S471-I474 WeakPolarHBondContact O-CG1 3.49Å
472D77.3Confident83.3Confident4 Ų444.4 Ų44.42%0.02122%0.223CC..Hα-helixtrans-87.7-42.2179-64.7-28.7000111.4E468 A469 F470 I474 T475 R550E468-D472 HydrophobicContact CG-CB 4.43Å; A469-D472 HydrophobicContact CB-CB 4.31Å; A469-D472 CarbonylContact O-C 3.55Å; A469-D472 WeakPolarHBondContact O-CA 3.44Å; A469-D472 WeakPolarHBondContact O-CB 2.97Å; A469-D472 PolarHBondContact O-N 3Å; F470-D472 PolarHBondContact O-N 2.92Å; F470-D472 VanDerWaalsContact O-N 3.13Å; D472-I474 VanDerWaalsContact C-N 3.28Å; D472-I474 PolarHBondContact O-N 2.85Å; D472-T475 WeakPolarHBondContact O-CB 3.38Å; D472-T475 WeakPolarHBondContact O-CG2 3.49Å; D472-T475 PolarHBondContact O-N 3.46Å; D472-R550 PolarHBondContact O-NH2 3.1Å; D472-R550 WeakPolarHBondContact OD1-CD 3.48Å; D472-R550 IonicContact OD1-CZ 2.81Å; D472-R550 IonicContact OD1-NE 2.62Å; D472-R550 PolarHBondContact OD1-NE 3.48Å; D472-R550 IonicContact OD1-NH2 2.63Å
473G74.3Confident82.8Confident0 Ų046.1 Ų46.10%024%0.235CC..Hα-helixtrans-68-22.6-17800000114.6S293 P294 D295 E468 A469 F470 T475S293-G473 WeakPolarHBondContact CB-O 3.41Å; P294-G473 WeakPolarHBondContact CD-O 3.37Å; D295-G473 WeakPolarHBondContact CB-O 3.38Å; D295-G473 PolarHBondContact N-O 3.39Å; E468-G473 WeakPolarHBondContact OE1-CA 3.41Å; A469-G473 PolarHBondContact O-N 2.9Å; F470-G473 PolarHBondContact O-N 2.9Å; G473-T475 PolarHBondContact O-N 3.2Å
474I80.5Confident82.4Confident0 Ų047 Ų470%024%0.24CC..THydrogen-bonded Turntrans-80.83.2176.366.4174.8000114.4I288 M290 F315 F470 S471 D472 W481I288-I474 VanDerWaalsContact O-CG2 3.26Å; I288-I474 WeakPolarHBondContact O-CG2 3.31Å; M290-I474 WeakPolarHBondContact CB-O 3.14Å; M290-I474 WeakPolarHBondContact CG-O 3.48Å; M290-I474 PolarHBondContact N-O 3.42Å; F315-I474 HydrophobicContact CE1-CB 4.25Å; F315-I474 HydrophobicContact CE1-CD1 4.09Å; F315-I474 HydrophobicContact CE1-CG1 4.47Å; F315-I474 HydrophobicContact CZ-CD1 3.93Å; F315-I474 HydrophobicContact CZ-CG1 4.47Å; F470-I474 HydrophobicContact CD2-CG2 4.42Å; F470-I474 HydrophobicContact CE2-CG2 4.09Å; F470-I474 HydrophobicContact CZ-CG2 4.2Å; F470-I474 WeakPolarHBondContact O-CG2 3.41Å; F470-I474 PolarHBondContact O-N 3.25Å; S471-I474 WeakPolarHBondContact O-CG1 3.49Å; D472-I474 VanDerWaalsContact C-N 3.28Å; D472-I474 PolarHBondContact O-N 2.85Å; I474-W481 HydrophobicContact CD1-CG 4.45Å
475T80.4Confident82.1Confident14 Ų1443.1 Ų43.19%0.08623%0.225CC..  trans-69.1144.7-175.9-178.10000114.3S293 P294 D472 G473 S480S293-T475 VanDerWaalsContact CA-O 3.23Å; S293-T475 WeakPolarHBondContact CA-O 3.19Å; S293-T475 WeakPolarHBondContact CB-O 3.28Å; P294-T475 HydrophobicContact CG-CG2 4.33Å; D472-T475 WeakPolarHBondContact O-CB 3.38Å; D472-T475 WeakPolarHBondContact O-CG2 3.49Å; D472-T475 PolarHBondContact O-N 3.46Å; G473-T475 PolarHBondContact O-N 3.2Å; T475-S480 WeakPolarHBondContact OG1-CA 3.12Å; T475-S480 WeakPolarHBondContact OG1-CB 3.12Å
476S78Confident81.9Confident26 Ų2642.1 Ų42.118%0.18222%0.223CC..  trans-72.4159.9164840000111K478 K479S476-K478 VanDerWaalsContact C-N 3.27Å; S476-K478 PolarHBondContact O-N 3Å; S476-K478 PolarHBondContact OG-N 3.48Å; S476-K479 PolarHBondContact OG-N 2.86Å; S476-K479 PolarHBondContact OG-O 3.27Å
477V72.4Confident82Confident127 Ų12741.7 Ų41.777%0.7722%0.216SC*.SBendtrans-66.7-29.2172.7-177.30000111.9
478K75.3Confident82.4Confident209 Ų20942.9 Ų42.991%0.90922%0.22SC*.SBendtrans-80.6-44.5-175.1-67.3-178.7-179.6175.20112.7S476S476-K478 VanDerWaalsContact C-N 3.27Å; S476-K478 PolarHBondContact O-N 3Å; S476-K478 PolarHBondContact OG-N 3.48Å
479K80.4Confident83Confident76 Ų7640.6 Ų40.633%0.3321%0.209SC..SBendtrans-153.8138.9-177.3-165.9174.6-177.9175.70110.8S476 I484 D487S476-K479 PolarHBondContact OG-N 2.86Å; S476-K479 PolarHBondContact OG-O 3.27Å; K479-I484 HydrophobicContact CB-CD1 4.35Å; K479-I484 HydrophobicContact CB-CG1 4.38Å; K479-I484 HydrophobicContact CD-CG1 3.77Å; K479-I484 HydrophobicContact CG-CD1 4.41Å; K479-I484 HydrophobicContact CG-CG1 3.93Å; K479-D487 IonicContact NZ-OD1 3.29Å; K479-D487 PolarHBondContact NZ-OD1 3.37Å; K479-D487 VanDerWaalsContact NZ-OD1 3.1Å; K479-D487 IonicContact NZ-OD2 3.55Å; K479-D487 PolarHBondContact NZ-OD2 2.76Å
480S83Confident83.8Confident9 Ų943.1 Ų43.16%0.06322%0.219CC..  trans-76.9149.3-178.3820000114.2T475 F482 S483 I484 R550T475-S480 WeakPolarHBondContact OG1-CA 3.12Å; T475-S480 WeakPolarHBondContact OG1-CB 3.12Å; S480-F482 PolarHBondContact O-N 3.14Å; S480-S483 PolarHBondContact O-N 3.11Å; S480-S483 WeakPolarHBondContact OG-CB 2.84Å; S480-S483 PolarHBondContact OG-N 2.65Å; S480-S483 PolarHBondContact OG-OG 2.86Å; S480-I484 WeakPolarHBondContact O-CG1 3.48Å; S480-I484 PolarHBondContact O-N 2.92Å; S480-R550 PolarHBondContact OG-NH1 2.82Å
481W85.7Confident84.4Confident1 Ų147.8 Ų47.80%0.00424%0.241CC..Hα-helixtrans-55-43.7173.5172.7-127.6000111.1M290 F315 G320 I321 R340 V343 I474 S483 I484 L485M290-W481 HydrophobicContact CE-CB 4.2Å; M290-W481 HydrophobicContact CE-CD2 4.43Å; M290-W481 HydrophobicContact CE-CE3 3.73Å; F315-W481 HydrophobicContact CE2-CD2 4.48Å; F315-W481 HydrophobicContact CE2-CE3 4.29Å; G320-W481 VanDerWaalsContact C-CH2 3.42Å; I321-W481 HydrophobicContact CG1-CH2 4.12Å; I321-W481 HydrophobicContact CG1-CZ3 4.21Å; R340-W481 PolarHBondContact O-NE1 3.21Å; V343-W481 HydrophobicContact CB-CZ2 4.19Å; V343-W481 HydrophobicContact CG1-CH2 4.48Å; V343-W481 HydrophobicContact CG1-CZ2 3.93Å; V343-W481 HydrophobicContact CG2-CZ2 4.12Å; I474-W481 HydrophobicContact CD1-CG 4.45Å; W481-S483 PolarHBondContact O-N 3.18Å; W481-I484 HydrophobicContact CE3-CB 4.32Å; W481-I484 HydrophobicContact CE3-CG2 4.1Å; W481-I484 HydrophobicContact CZ3-CG2 3.98Å; W481-I484 PolarHBondContact O-N 3.33Å; W481-L485 HydrophobicContact CD2-CD1 4.07Å; W481-L485 HydrophobicContact CD2-CG 4.07Å; W481-L485 VanDerWaalsContact CE2-CD1 3.46Å; W481-L485 HydrophobicContact CE3-CG 4.26Å; W481-L485 HydrophobicContact CG-CD1 4.46Å; W481-L485 HydrophobicContact CH2-CD1 4.33Å; W481-L485 HydrophobicContact CH2-CD2 3.53Å; W481-L485 HydrophobicContact CH2-CG 3.79Å; W481-L485 HydrophobicContact CZ2-CD1 3.62Å; W481-L485 HydrophobicContact CZ2-CD2 3.54Å; W481-L485 HydrophobicContact CZ2-CG 3.6Å; W481-L485 HydrophobicContact CZ3-CD2 4.23Å; W481-L485 HydrophobicContact CZ3-CG 4.13Å; W481-L485 WeakPolarHBondContact O-CG 3.34Å; W481-L485 PolarHBondContact O-N 3.42Å
482F85.5Confident85.4Confident44 Ų4451.3 Ų51.319%0.19326%0.256CS..Hα-helixtrans-54.9-50.4171.5166.7-106.3000112.5S480 I484 L485 Q486S480-F482 PolarHBondContact O-N 3.14Å; F482-I484 VanDerWaalsContact C-N 3.32Å; F482-I484 PolarHBondContact O-N 2.8Å; F482-L485 WeakPolarHBondContact O-CB 3.43Å; F482-L485 PolarHBondContact O-N 3.42Å; F482-Q486 HydrophobicContact CD2-CG 4.28Å; F482-Q486 HydrophobicContact CE1-CG 4.14Å; F482-Q486 HydrophobicContact CE2-CG 3.74Å; F482-Q486 HydrophobicContact CZ-CG 3.67Å; F482-Q486 WeakPolarHBondContact O-CG 3.22Å; F482-Q486 PolarHBondContact O-N 3.39Å
483S86.4Confident86.2Confident40 Ų4051.1 Ų51.128%0.2826%0.255SS..Hα-helixtrans-65-36.2179.3-550000112.4S480 W481 L485 Q486 D487S480-S483 PolarHBondContact O-N 3.11Å; S480-S483 WeakPolarHBondContact OG-CB 2.84Å; S480-S483 PolarHBondContact OG-N 2.65Å; S480-S483 PolarHBondContact OG-OG 2.86Å; W481-S483 PolarHBondContact O-N 3.18Å; S483-L485 VanDerWaalsContact C-N 3.34Å; S483-Q486 PolarHBondContact O-N 2.76Å; S483-D487 PolarHBondContact O-N 3.08Å; S483-D487 VanDerWaalsContact O-N 3.07Å
484I89.7Confident87.1Confident23 Ų2355.2 Ų55.212%0.11828%0.277CS..Hα-helixtrans-63.7-42.9175.3-73.2159.8000110.5M290 I321 K479 S480 W481 F482 Y488M290-I484 HydrophobicContact CE-CD1 3.65Å; M290-I484 HydrophobicContact SD-CD1 4.05Å; I321-I484 HydrophobicContact CD1-CG2 4.08Å; K479-I484 HydrophobicContact CB-CD1 4.35Å; K479-I484 HydrophobicContact CB-CG1 4.38Å; K479-I484 HydrophobicContact CD-CG1 3.77Å; K479-I484 HydrophobicContact CG-CD1 4.41Å; K479-I484 HydrophobicContact CG-CG1 3.93Å; S480-I484 WeakPolarHBondContact O-CG1 3.48Å; S480-I484 PolarHBondContact O-N 2.92Å; W481-I484 HydrophobicContact CE3-CB 4.32Å; W481-I484 HydrophobicContact CE3-CG2 4.1Å; W481-I484 HydrophobicContact CZ3-CG2 3.98Å; W481-I484 PolarHBondContact O-N 3.33Å; F482-I484 VanDerWaalsContact C-N 3.32Å; F482-I484 PolarHBondContact O-N 2.8Å; I484-Y488 PolarHBondContact O-N 2.82Å
485L89.4Confident87.8Confident0 Ų060 Ų600%030%0.302CS..Hα-helixtrans-62-46174.5-77.9172.1000111.8L324 R340 W481 F482 S483 Y488 I489L324-L485 HydrophobicContact CD1-CD2 3.79Å; L324-L485 HydrophobicContact CD2-CD2 4.23Å; L324-L485 HydrophobicContact CG-CD2 4.49Å; R340-L485 HydrophobicContact CG-CD1 4.06Å; W481-L485 HydrophobicContact CD2-CD1 4.07Å; W481-L485 HydrophobicContact CD2-CG 4.07Å; W481-L485 VanDerWaalsContact CE2-CD1 3.46Å; W481-L485 HydrophobicContact CE3-CG 4.26Å; W481-L485 HydrophobicContact CG-CD1 4.46Å; W481-L485 HydrophobicContact CH2-CD1 4.33Å; W481-L485 HydrophobicContact CH2-CD2 3.53Å; W481-L485 HydrophobicContact CH2-CG 3.79Å; W481-L485 HydrophobicContact CZ2-CD1 3.62Å; W481-L485 HydrophobicContact CZ2-CD2 3.54Å; W481-L485 HydrophobicContact CZ2-CG 3.6Å; W481-L485 HydrophobicContact CZ3-CD2 4.23Å; W481-L485 HydrophobicContact CZ3-CG 4.13Å; W481-L485 WeakPolarHBondContact O-CG 3.34Å; W481-L485 PolarHBondContact O-N 3.42Å; F482-L485 WeakPolarHBondContact O-CB 3.43Å; F482-L485 PolarHBondContact O-N 3.42Å; S483-L485 VanDerWaalsContact C-N 3.34Å; L485-Y488 PolarHBondContact O-N 3.38Å; L485-I489 HydrophobicContact CB-CD1 4.31Å; L485-I489 WeakPolarHBondContact O-CB 3.32Å; L485-I489 WeakPolarHBondContact O-CD1 3.1Å; L485-I489 WeakPolarHBondContact O-CG1 3.38Å; L485-I489 PolarHBondContact O-N 3.07Å
486Q90Very high88.4Confident39 Ų3966.3 Ų66.318%0.18233%0.326CS..Hα-helixtrans-58.1-51.6178.1-67.2-46.5-80.800111.4F482 S483 Y488 I489 D490 E514F482-Q486 HydrophobicContact CD2-CG 4.28Å; F482-Q486 HydrophobicContact CE1-CG 4.14Å; F482-Q486 HydrophobicContact CE2-CG 3.74Å; F482-Q486 HydrophobicContact CZ-CG 3.67Å; F482-Q486 WeakPolarHBondContact O-CG 3.22Å; F482-Q486 PolarHBondContact O-N 3.39Å; S483-Q486 PolarHBondContact O-N 2.76Å; Q486-Y488 PolarHBondContact O-N 3.45Å; Q486-I489 PolarHBondContact O-N 3.14Å; Q486-I489 VanDerWaalsContact O-N 3.13Å; Q486-D490 WeakPolarHBondContact O-CB 3.42Å; Q486-D490 PolarHBondContact O-N 3.37Å; Q486-E514 PolarHBondContact NE2-OE2 3.03Å
487D92.9Very high89.2Confident79 Ų7967.7 Ų67.742%0.42233%0.331SS..Hα-helixtrans-56.5-37.3179.7-82.955.2000113.3K479 S483 Q491K479-D487 IonicContact NZ-OD1 3.29Å; K479-D487 PolarHBondContact NZ-OD1 3.37Å; K479-D487 VanDerWaalsContact NZ-OD1 3.1Å; K479-D487 IonicContact NZ-OD2 3.55Å; K479-D487 PolarHBondContact NZ-OD2 2.76Å; S483-D487 PolarHBondContact O-N 3.08Å; S483-D487 VanDerWaalsContact O-N 3.07Å; D487-Q491 WeakPolarHBondContact O-CG 3.28Å; D487-Q491 PolarHBondContact O-NE2 3.05Å
488Y94.7Very high90.3Very high65 Ų6563.8 Ų63.826%0.25531%0.305SS..Hα-helixtrans-71.7-47.6176.9174.3-104.6000111.1I321 I484 L485 Q486 Q491 Q492 Y517I321-Y488 HydrophobicContact CD1-CD2 4.2Å; I321-Y488 HydrophobicContact CD1-CG 3.95Å; I321-Y488 HydrophobicContact CG1-CD1 4.45Å; I321-Y488 HydrophobicContact CG1-CG 4.36Å; I321-Y488 HydrophobicContact CG2-CD1 3.79Å; I321-Y488 HydrophobicContact CG2-CD2 4Å; I321-Y488 HydrophobicContact CG2-CE1 3.56Å; I321-Y488 HydrophobicContact CG2-CE2 3.8Å; I321-Y488 HydrophobicContact CG2-CG 4Å; I484-Y488 PolarHBondContact O-N 2.82Å; L485-Y488 PolarHBondContact O-N 3.38Å; Q486-Y488 PolarHBondContact O-N 3.45Å; Y488-Q491 WeakPolarHBondContact O-CB 3.38Å; Y488-Q491 PolarHBondContact O-N 3.03Å; Y488-Q492 HydrophobicContact CD1-CG 4.45Å; Y488-Q492 HydrophobicContact CE1-CG 4.03Å; Y488-Q492 HydrophobicContact CE2-CG 4.49Å; Y488-Q492 WeakPolarHBondContact O-CG 3.46Å; Y488-Y517 HydrophobicContact CE1-CE1 4.16Å; Y488-Y517 AromaticContact CE1-CZ 3.81Å; Y488-Y517 WeakPolarHBondContact CE1-OH 3.43Å; Y488-Y517 PolarHBondContact OH-OH 3.26Å
489I94.2Very high91.3Very high0 Ų061.2 Ų61.20%030%0.296CS..Hα-helixtrans-68.3-36.3-175.7-71166.5000111.9L485 Q486 Q491 Q492 V493 K513 E514 Y517 Y518L485-I489 HydrophobicContact CB-CD1 4.31Å; L485-I489 WeakPolarHBondContact O-CB 3.32Å; L485-I489 WeakPolarHBondContact O-CD1 3.1Å; L485-I489 WeakPolarHBondContact O-CG1 3.38Å; L485-I489 PolarHBondContact O-N 3.07Å; Q486-I489 PolarHBondContact O-N 3.14Å; Q486-I489 VanDerWaalsContact O-N 3.13Å; I489-Q491 PolarHBondContact O-N 2.95Å; I489-Q491 VanDerWaalsContact O-N 3.14Å; I489-Q492 WeakPolarHBondContact O-CA 3.32Å; I489-Q492 PolarHBondContact O-N 3.38Å; I489-V493 PolarHBondContact O-N 2.91Å; I489-K513 HydrophobicContact CG2-CB 3.86Å; I489-E514 HydrophobicContact CD1-CB 3.86Å; I489-E514 HydrophobicContact CD1-CG 3.73Å; I489-E514 HydrophobicContact CG2-CB 4.42Å; I489-Y517 HydrophobicContact CD1-CD1 4.24Å; I489-Y517 HydrophobicContact CG1-CD1 3.92Å; I489-Y517 HydrophobicContact CG1-CE1 4.49Å; I489-Y517 HydrophobicContact CG1-CG 4.16Å; I489-Y518 HydrophobicContact CD1-CE1 4.25Å
490D93.4Very high92Very high82 Ų8261 Ų6144%0.43930%0.295SS..THydrogen-bonded Turntrans-60.4-22.6175.5-81.1-30.3000112.6Q486 K513Q486-D490 WeakPolarHBondContact O-CB 3.42Å; Q486-D490 PolarHBondContact O-N 3.37Å; D490-K513 WeakPolarHBondContact OD1-CD 3.33Å; D490-K513 IonicContact OD1-NZ 3.04Å
491Q94.6Very high92.7Very high149 Ų14960.7 Ų60.770%0.69629%0.293SS*.THydrogen-bonded Turntrans-85.8-16.6173.3-60.1169.535.500113D487 Y488 I489D487-Q491 WeakPolarHBondContact O-CG 3.28Å; D487-Q491 PolarHBondContact O-NE2 3.05Å; Y488-Q491 WeakPolarHBondContact O-CB 3.38Å; Y488-Q491 PolarHBondContact O-N 3.03Å; I489-Q491 PolarHBondContact O-N 2.95Å; I489-Q491 VanDerWaalsContact O-N 3.14Å
492Q94.5Very high93.2Very high90 Ų9063.4 Ų63.442%0.42132%0.316SS..THydrogen-bonded Turntrans-98.3-31.9-178.7-54.9-51-56.700112.8Y488 I489 Y517Y488-Q492 HydrophobicContact CD1-CG 4.45Å; Y488-Q492 HydrophobicContact CE1-CG 4.03Å; Y488-Q492 HydrophobicContact CE2-CG 4.49Å; Y488-Q492 WeakPolarHBondContact O-CG 3.46Å; I489-Q492 WeakPolarHBondContact O-CA 3.32Å; I489-Q492 PolarHBondContact O-N 3.38Å; Q492-Y517 HydrophobicContact CB-CD2 3.83Å; Q492-Y517 HydrophobicContact CB-CE2 3.79Å; Q492-Y517 HydrophobicContact CG-CD2 4.27Å; Q492-Y517 HydrophobicContact CG-CE2 3.79Å
493V94.7Very high93.7Very high1 Ų168 Ų681%0.00634%0.338CS..  trans-123.6113.6-175.8-1740000109.5I489 L497 K513 Y516 Y517I489-V493 PolarHBondContact O-N 2.91Å; V493-L497 HydrophobicContact CG1-CB 4.09Å; V493-L497 HydrophobicContact CG1-CD1 4.44Å; V493-K513 HydrophobicContact CB-CB 4.09Å; V493-K513 HydrophobicContact CB-CG 4.19Å; V493-K513 HydrophobicContact CG1-CB 4.21Å; V493-K513 HydrophobicContact CG1-CG 4.03Å; V493-K513 VanDerWaalsContact O-CD 3.22Å; V493-K513 WeakPolarHBondContact O-CD 3.46Å; V493-K513 WeakPolarHBondContact O-CE 3.5Å; V493-K513 PolarHBondContact O-NZ 3.3Å; V493-Y516 HydrophobicContact CG1-CD1 3.87Å; V493-Y516 HydrophobicContact CG1-CE1 4.48Å; V493-Y516 HydrophobicContact CG1-CG 4.08Å; V493-Y516 HydrophobicContact CG2-CD1 4.09Å; V493-Y517 HydrophobicContact CG2-CD2 4.21Å
494D94.1Very high94.2Very high85 Ų8571 Ų7146%0.45535%0.346SS..  trans-81167.6173.167.537.2000112.3Y496 L497 L498D494-Y496 VanDerWaalsContact C-N 3.25Å; D494-Y496 PolarHBondContact O-N 3.36Å; D494-Y496 WeakPolarHBondContact OD1-CB 3.49Å; D494-Y496 PolarHBondContact OD1-N 3.26Å; D494-Y496 VanDerWaalsContact OD1-N 3.1Å; D494-L497 PolarHBondContact O-N 3.19Å; D494-L497 WeakPolarHBondContact OD1-CG 3.19Å; D494-L497 PolarHBondContact OD1-N 3.27Å; D494-L498 PolarHBondContact O-N 3.05Å
495D94Very high94.6Very high101 Ų10170.6 Ų70.654%0.5434%0.343SS..Hα-helixtrans-65.6-30.5-177.8-65.3-15.5000112L498 E499 K513D495-L498 PolarHBondContact O-N 3.34Å; D495-E499 WeakPolarHBondContact O-CG 3.41Å; D495-E499 PolarHBondContact O-N 2.82Å; D495-K513 WeakPolarHBondContact OD1-CE 3.47Å; D495-K513 IonicContact OD1-NZ 3.69Å; D495-K513 PolarHBondContact OD1-NZ 2.76Å
496Y94.6Very high94.9Very high147 Ų14775.5 Ų75.558%0.57638%0.375SS*.Hα-helixtrans-65.9-42.4179.1176-97.2000111.8D494 L498 E499 K500D494-Y496 VanDerWaalsContact C-N 3.25Å; D494-Y496 PolarHBondContact O-N 3.36Å; D494-Y496 WeakPolarHBondContact OD1-CB 3.49Å; D494-Y496 PolarHBondContact OD1-N 3.26Å; D494-Y496 VanDerWaalsContact OD1-N 3.1Å; Y496-L498 VanDerWaalsContact C-N 3.31Å; Y496-L498 PolarHBondContact O-N 2.96Å; Y496-E499 PolarHBondContact O-N 3.43Å; Y496-K500 HydrophobicContact CE1-CG 4.25Å; Y496-K500 HydrophobicContact CE2-CG 4.25Å; Y496-K500 WeakPolarHBondContact O-CB 3.32Å; Y496-K500 WeakPolarHBondContact O-CG 3.39Å; Y496-K500 PolarHBondContact O-N 2.71Å; Y496-K500 VanDerWaalsContact O-N 3.08Å
497L94.6Very high95.3Very high55 Ų5577.7 Ų77.729%0.28838%0.384SS..Hα-helixtrans-60.4-41.4174.7-71.2177.5000111.7V493 D494 K500 A501 Y516V493-L497 HydrophobicContact CG1-CB 4.09Å; V493-L497 HydrophobicContact CG1-CD1 4.44Å; D494-L497 PolarHBondContact O-N 3.19Å; D494-L497 WeakPolarHBondContact OD1-CG 3.19Å; D494-L497 PolarHBondContact OD1-N 3.27Å; L497-K500 CarbonylContact O-C 3.32Å; L497-K500 PolarHBondContact O-N 3.1Å; L497-A501 PolarHBondContact O-N 3.48Å; L497-A501 VanDerWaalsContact O-N 3.13Å; L497-Y516 HydrophobicContact CB-CE1 4.37Å; L497-Y516 HydrophobicContact CB-CE2 4.45Å; L497-Y516 WeakPolarHBondContact O-CE2 3.29Å
498L94.8Very high95.4Very high44 Ų4475.8 Ų75.823%0.2337%0.374CS..Hα-helixtrans-68.9-42.1178.3-175.862.4000111.9D494 D495 Y496 K500 A501 K513 Y516D494-L498 PolarHBondContact O-N 3.05Å; D495-L498 PolarHBondContact O-N 3.34Å; Y496-L498 VanDerWaalsContact C-N 3.31Å; Y496-L498 PolarHBondContact O-N 2.96Å; L498-K500 PolarHBondContact O-N 2.93Å; L498-A501 HydrophobicContact CD1-CB 4.41Å; L498-A501 WeakPolarHBondContact O-CB 3.49Å; L498-A501 PolarHBondContact O-N 2.9Å; L498-K513 HydrophobicContact CD2-CG 4.14Å; L498-Y516 HydrophobicContact CD1-CD2 4.5Å
499E95.9Very high95.5Very high155 Ų15574.8 Ų74.872%0.72438%0.375SS*.Hα-helixtrans-57.4-35.1173.7-76.5178.7-178.200111.9D495 Y496 A501D495-E499 WeakPolarHBondContact O-CG 3.41Å; D495-E499 PolarHBondContact O-N 2.82Å; Y496-E499 PolarHBondContact O-N 3.43Å; E499-A501 VanDerWaalsContact C-N 3.35Å
500K96.3Very high95.5Very high72 Ų7275 Ų7531%0.31338%0.376SS..THydrogen-bonded Turntrans-89.25.6178.4-65.7-72.4174.5178.10114.1Y496 L497 L498 A502 E503 K504Y496-K500 HydrophobicContact CE1-CG 4.25Å; Y496-K500 HydrophobicContact CE2-CG 4.25Å; Y496-K500 WeakPolarHBondContact O-CB 3.32Å; Y496-K500 WeakPolarHBondContact O-CG 3.39Å; Y496-K500 PolarHBondContact O-N 2.71Å; Y496-K500 VanDerWaalsContact O-N 3.08Å; L497-K500 CarbonylContact O-C 3.32Å; L497-K500 PolarHBondContact O-N 3.1Å; L498-K500 PolarHBondContact O-N 2.93Å; K500-A502 VanDerWaalsContact C-N 3.29Å; K500-A502 PolarHBondContact O-N 3.33Å; K500-E503 VanDerWaalsContact CD-CD 3.43Å; K500-E503 VanDerWaalsContact CD-OE1 3.25Å; K500-E503 WeakPolarHBondContact CD-OE1 3.01Å; K500-E503 WeakPolarHBondContact CD-OE2 3.21Å; K500-E503 IonicContact NZ-OE1 3.43Å; K500-E503 PolarHBondContact NZ-OE1 3.32Å; K500-E503 IonicContact NZ-OE2 3.13Å; K500-E503 PolarHBondContact NZ-OE2 3.41Å; K500-E503 PolarHBondContact O-N 2.65Å; K500-E503 VanDerWaalsContact O-N 3.11Å; K500-K504 PolarHBondContact O-N 2.95Å
501A96.3Very high95.5Very high2 Ų279.3 Ų79.32%0.01739%0.391CS..Hα-helixtrans-59.7-36.5-175.800000113.3L497 L498 E499 E503 K504 Y505 T509 P510 Y516L497-A501 PolarHBondContact O-N 3.48Å; L497-A501 VanDerWaalsContact O-N 3.13Å; L498-A501 HydrophobicContact CD1-CB 4.41Å; L498-A501 WeakPolarHBondContact O-CB 3.49Å; L498-A501 PolarHBondContact O-N 2.9Å; E499-A501 VanDerWaalsContact C-N 3.35Å; A501-E503 VanDerWaalsContact C-N 3.28Å; A501-E503 PolarHBondContact O-N 2.85Å; A501-K504 PolarHBondContact O-N 2.68Å; A501-Y505 CarbonylContact O-C 3.49Å; A501-Y505 WeakPolarHBondContact O-CA 3.4Å; A501-Y505 PolarHBondContact O-N 2.81Å; A501-T509 HydrophobicContact CB-CG2 3.96Å; A501-P510 HydrophobicContact CB-CB 4.5Å; A501-Y516 HydrophobicContact CB-CD2 3.71Å; A501-Y516 HydrophobicContact CB-CE2 3.8Å
502A96.9Very high95.4Very high58 Ų5873.5 Ų73.548%0.47937%0.366SS..Hα-helixtrans-66.8-29.1179.600000113.1K500 P506 T509K500-A502 VanDerWaalsContact C-N 3.29Å; K500-A502 PolarHBondContact O-N 3.33Å; A502-P506 WeakPolarHBondContact O-CA 3.45Å; A502-T509 HydrophobicContact CB-CG2 3.93Å
503E96.8Very high95.4Very high140 Ų14071 Ų7165%0.65435%0.353SS*.Hα-helixtrans-73.9-41.5177.4-62.6176-160.200110.8K500 A501K500-E503 VanDerWaalsContact CD-CD 3.43Å; K500-E503 VanDerWaalsContact CD-OE1 3.25Å; K500-E503 WeakPolarHBondContact CD-OE1 3.01Å; K500-E503 WeakPolarHBondContact CD-OE2 3.21Å; K500-E503 IonicContact NZ-OE1 3.43Å; K500-E503 PolarHBondContact NZ-OE1 3.32Å; K500-E503 IonicContact NZ-OE2 3.13Å; K500-E503 PolarHBondContact NZ-OE2 3.41Å; K500-E503 PolarHBondContact O-N 2.65Å; K500-E503 VanDerWaalsContact O-N 3.11Å; A501-E503 VanDerWaalsContact C-N 3.28Å; A501-E503 PolarHBondContact O-N 2.85Å
504K96.8Very high95.4Very high105 Ų10570.9 Ų70.946%0.45735%0.353SS..Hα-helixtrans-80.3-40-179.6-166.3-179.8-180-1760112.6K500 A501 Y516 E520K500-K504 PolarHBondContact O-N 2.95Å; A501-K504 PolarHBondContact O-N 2.68Å; K504-Y516 VanDerWaalsContact CD-OH 3.3Å; K504-Y516 WeakPolarHBondContact CD-OH 3.4Å; K504-E520 IonicContact NZ-OE1 2.66Å
505Y97.3Very high95.5Very high13 Ų1367 Ų675%0.05133%0.332CS..  trans-128.576.6-173.9-53.4-48.9000110.5A501 F507 T509 P510 Y516 R519 E523A501-Y505 CarbonylContact O-C 3.49Å; A501-Y505 WeakPolarHBondContact O-CA 3.4Å; A501-Y505 PolarHBondContact O-N 2.81Å; Y505-F507 VanDerWaalsContact C-N 3.32Å; Y505-F507 PolarHBondContact O-N 2.95Å; Y505-T509 WeakPolarHBondContact O-CA 3.28Å; Y505-T509 WeakPolarHBondContact O-CB 3.41Å; Y505-T509 PolarHBondContact O-OG1 3.07Å; Y505-P510 HydrophobicContact CD2-CG 3.95Å; Y505-Y516 HydrophobicContact CD2-CD2 4.35Å; Y505-Y516 HydrophobicContact CD2-CE2 4.12Å; Y505-Y516 HydrophobicContact CE2-CD2 4.22Å; Y505-Y516 HydrophobicContact CE2-CE1 4.18Å; Y505-Y516 AromaticContact CE2-CE2 3.87Å; Y505-Y516 HydrophobicContact CE2-CE2 3.87Å; Y505-Y516 AromaticContact CE2-CZ 3.85Å; Y505-R519 HydrophobicContact CD1-CG 4.09Å; Y505-R519 HydrophobicContact CD2-CG 3.78Å; Y505-R519 HydrophobicContact CE1-CG 4.2Å; Y505-R519 HydrophobicContact CE2-CB 4.4Å; Y505-R519 HydrophobicContact CE2-CG 3.86Å; Y505-R519 HydrophobicContact CG-CG 3.88Å; Y505-E523 HydrophobicContact CD1-CG 4.29Å; Y505-E523 HydrophobicContact CE1-CB 4.41Å; Y505-E523 HydrophobicContact CE1-CG 3.76Å
506P96.6Very high95.6Very high104 Ų10462.3 Ų62.368%0.67531%0.307SS*.  trans-70.3-27.3-176.827-35.5000113.4A502 T509A502-P506 WeakPolarHBondContact O-CA 3.45Å; P506-T509 PolarHBondContact O-OG1 2.89Å
507F96.5Very high95.8Very high85 Ų8556.9 Ų56.937%0.37329%0.286SS..SBendtrans-91.2128.1175-177.8-94.1000110.2Y505 T509 R519 S530 L533Y505-F507 VanDerWaalsContact C-N 3.32Å; Y505-F507 PolarHBondContact O-N 2.95Å; F507-T509 VanDerWaalsContact C-N 3.31Å; F507-T509 PolarHBondContact O-N 2.84Å; F507-R519 PolarHBondContact O-NH1 2.82Å; F507-R519 PolarHBondContact O-NH2 3.43Å; F507-S530 WeakPolarHBondContact CE1-O 3.41Å; F507-L533 WeakPolarHBondContact CE1-O 3.41Å
508N95.3Very high96Very high39 Ų3954.2 Ų54.221%0.20927%0.272CS..SBendtrans46.854.8-176.1-82.6-17.5000112.1Y334 P510 R519 L533 P534 H535 F536Y334-N508 HydrophobicContact CE2-CB 4.18Å; Y334-N508 VanDerWaalsContact OH-CB 3.28Å; Y334-N508 WeakPolarHBondContact OH-CB 3.45Å; N508-P510 WeakPolarHBondContact O-CD 3.33Å; N508-R519 PolarHBondContact O-NH1 3.1Å; N508-L533 PolarHBondContact ND2-O 2.78Å; N508-P534 PolarHBondContact ND2-O 3.43Å; N508-P534 PolarHBondContact OD1-O 2.93Å; N508-H535 PolarHBondContact ND2-N 2.58Å; N508-F536 HydrophobicContact CB-CE2 4.2Å
509T96.6Very high96.1Very high43 Ų4352.3 Ų52.326%0.26426%0.262SS..  trans-53.3125.1-177.2-56.20000111.2A501 A502 Y505 P506 F507 K511A501-T509 HydrophobicContact CB-CG2 3.96Å; A502-T509 HydrophobicContact CB-CG2 3.93Å; Y505-T509 WeakPolarHBondContact O-CA 3.28Å; Y505-T509 WeakPolarHBondContact O-CB 3.41Å; Y505-T509 PolarHBondContact O-OG1 3.07Å; P506-T509 PolarHBondContact O-OG1 2.89Å; F507-T509 VanDerWaalsContact C-N 3.31Å; F507-T509 PolarHBondContact O-N 2.84Å; T509-K511 PolarHBondContact O-N 3.19Å
510P94.9Very high96.2Very high5 Ų548.6 Ų48.63%0.03224%0.244CC..  trans-53.7134.3172.7-30.138000112.7A501 Y505 N508 S515 Y516 R519A501-P510 HydrophobicContact CB-CB 4.5Å; Y505-P510 HydrophobicContact CD2-CG 3.95Å; N508-P510 WeakPolarHBondContact O-CD 3.33Å; P510-S515 WeakPolarHBondContact CA-OG 3.49Å; P510-S515 WeakPolarHBondContact CB-OG 3.12Å; P510-Y516 HydrophobicContact CB-CD2 4.26Å; P510-Y516 HydrophobicContact CG-CD2 4.37Å; P510-R519 HydrophobicContact CG-CB 3.92Å; P510-R519 HydrophobicContact CG-CG 4.09Å
511K92.9Very high96.3Very high173 Ų17345.8 Ų45.875%0.75223%0.232SC*.  trans-107.8-11.3179.2-63.8-174.9179.8178.50113.5T509 S515T509-K511 PolarHBondContact O-N 3.19Å; K511-S515 PolarHBondContact N-OG 3.09Å; K511-S515 VanDerWaalsContact N-OG 3.09Å
512T93.3Very high96.4Very high27 Ų2745.7 Ų45.717%0.16623%0.232CC..SBendtrans-132.3155.7177.367.40000109.7E514 S515 Y516T512-E514 PolarHBondContact O-N 3.23Å; T512-S515 PolarHBondContact N-OG 2.99Å; T512-S515 PolarHBondContact O-N 2.84Å; T512-S515 VanDerWaalsContact O-N 3.15Å; T512-S515 PolarHBondContact O-OG 3.38Å; T512-S515 PolarHBondContact OG1-N 2.99Å; T512-S515 VanDerWaalsContact OG1-N 3.12Å; T512-S515 PolarHBondContact OG1-OG 3.21Å; T512-Y516 PolarHBondContact O-N 3.18Å
513K95.3Very high96.4Very high36 Ų3644.5 Ų44.516%0.15722%0.216CC..Hα-helixtrans-54.5-35.9174.3-71.5178.2171.6-179.40112.6I489 D490 V493 D495 L498 Y516 Y517I489-K513 HydrophobicContact CG2-CB 3.86Å; D490-K513 WeakPolarHBondContact OD1-CD 3.33Å; D490-K513 IonicContact OD1-NZ 3.04Å; V493-K513 HydrophobicContact CB-CB 4.09Å; V493-K513 HydrophobicContact CB-CG 4.19Å; V493-K513 HydrophobicContact CG1-CB 4.21Å; V493-K513 HydrophobicContact CG1-CG 4.03Å; V493-K513 VanDerWaalsContact O-CD 3.22Å; V493-K513 WeakPolarHBondContact O-CD 3.46Å; V493-K513 WeakPolarHBondContact O-CE 3.5Å; V493-K513 PolarHBondContact O-NZ 3.3Å; D495-K513 WeakPolarHBondContact OD1-CE 3.47Å; D495-K513 IonicContact OD1-NZ 3.69Å; D495-K513 PolarHBondContact OD1-NZ 2.76Å; L498-K513 HydrophobicContact CD2-CG 4.14Å; K513-Y516 WeakPolarHBondContact O-CB 3.43Å; K513-Y516 PolarHBondContact O-N 3.26Å; K513-Y517 WeakPolarHBondContact O-CB 3.26Å; K513-Y517 PolarHBondContact O-N 2.82Å
514E95Very high96.4Very high0 Ų044.1 Ų44.10%021%0.212CC..Hα-helixtrans-66.5-49.1175.4176.6173.3-172.900113.4I336 R340 Q486 I489 T512 Y516 Y517 Y518I336-E514 HydrophobicContact CG2-CG 4.46Å; R340-E514 WeakPolarHBondContact CG-OE1 3.31Å; R340-E514 IonicContact CZ-OE1 2.85Å; R340-E514 IonicContact CZ-OE2 2.82Å; R340-E514 IonicContact NE-OE1 3.41Å; R340-E514 PolarHBondContact NE-OE1 3.3Å; R340-E514 IonicContact NE-OE2 2.65Å; R340-E514 PolarHBondContact NE-OE2 3.44Å; R340-E514 VanDerWaalsContact NH2-CD 3.32Å; R340-E514 IonicContact NH2-OE1 3.32Å; R340-E514 PolarHBondContact NH2-OE1 2.99Å; R340-E514 IonicContact NH2-OE2 2.76Å; R340-E514 PolarHBondContact NH2-OE2 3.1Å; Q486-E514 PolarHBondContact NE2-OE2 3.03Å; I489-E514 HydrophobicContact CD1-CB 3.86Å; I489-E514 HydrophobicContact CD1-CG 3.73Å; I489-E514 HydrophobicContact CG2-CB 4.42Å; T512-E514 PolarHBondContact O-N 3.23Å; E514-Y516 PolarHBondContact O-N 3.11Å; E514-Y517 PolarHBondContact O-N 3.36Å; E514-Y518 HydrophobicContact CG-CD2 3.93Å; E514-Y518 HydrophobicContact CG-CE1 4.2Å; E514-Y518 HydrophobicContact CG-CE2 3.41Å; E514-Y518 VanDerWaalsContact CG-CE2 3.41Å; E514-Y518 PolarHBondContact O-N 3.34Å; E514-Y518 WeakPolarHBondContact OE1-CE2 3.35Å; E514-Y518 PolarHBondContact OE1-OH 3.4Å
515S95.1Very high96.4Very high2 Ų241.9 Ų41.91%0.01420%0.203CC..Hα-helixtrans-59.1-31.3173.455.20000111.9P510 K511 T512 R519P510-S515 WeakPolarHBondContact CA-OG 3.49Å; P510-S515 WeakPolarHBondContact CB-OG 3.12Å; K511-S515 PolarHBondContact N-OG 3.09Å; K511-S515 VanDerWaalsContact N-OG 3.09Å; T512-S515 PolarHBondContact N-OG 2.99Å; T512-S515 PolarHBondContact O-N 2.84Å; T512-S515 VanDerWaalsContact O-N 3.15Å; T512-S515 PolarHBondContact O-OG 3.38Å; T512-S515 PolarHBondContact OG1-N 2.99Å; T512-S515 VanDerWaalsContact OG1-N 3.12Å; T512-S515 PolarHBondContact OG1-OG 3.21Å; S515-R519 WeakPolarHBondContact O-CB 3.29Å; S515-R519 PolarHBondContact O-N 2.87Å
516Y97.2Very high96.3Very high4 Ų441.5 Ų41.52%0.01620%0.202CC..Hα-helixtrans-69.6-48.6177.2-169.7-74.3000110.8V493 L497 L498 A501 K504 Y505 P510 T512 K513 E514 Y518 R519 E520V493-Y516 HydrophobicContact CG1-CD1 3.87Å; V493-Y516 HydrophobicContact CG1-CE1 4.48Å; V493-Y516 HydrophobicContact CG1-CG 4.08Å; V493-Y516 HydrophobicContact CG2-CD1 4.09Å; L497-Y516 HydrophobicContact CB-CE1 4.37Å; L497-Y516 HydrophobicContact CB-CE2 4.45Å; L497-Y516 WeakPolarHBondContact O-CE2 3.29Å; L498-Y516 HydrophobicContact CD1-CD2 4.5Å; A501-Y516 HydrophobicContact CB-CD2 3.71Å; A501-Y516 HydrophobicContact CB-CE2 3.8Å; K504-Y516 VanDerWaalsContact CD-OH 3.3Å; K504-Y516 WeakPolarHBondContact CD-OH 3.4Å; Y505-Y516 HydrophobicContact CD2-CD2 4.35Å; Y505-Y516 HydrophobicContact CD2-CE2 4.12Å; Y505-Y516 HydrophobicContact CE2-CD2 4.22Å; Y505-Y516 HydrophobicContact CE2-CE1 4.18Å; Y505-Y516 AromaticContact CE2-CE2 3.87Å; Y505-Y516 HydrophobicContact CE2-CE2 3.87Å; Y505-Y516 AromaticContact CE2-CZ 3.85Å; P510-Y516 HydrophobicContact CB-CD2 4.26Å; P510-Y516 HydrophobicContact CG-CD2 4.37Å; T512-Y516 PolarHBondContact O-N 3.18Å; K513-Y516 WeakPolarHBondContact O-CB 3.43Å; K513-Y516 PolarHBondContact O-N 3.26Å; E514-Y516 PolarHBondContact O-N 3.11Å; Y516-Y518 PolarHBondContact O-N 3.22Å; Y516-R519 WeakPolarHBondContact O-CB 3.15Å; Y516-R519 PolarHBondContact O-N 3.05Å; Y516-E520 WeakPolarHBondContact O-CB 3.38Å; Y516-E520 PolarHBondContact O-N 2.77Å
517Y97.9Very high96.1Very high32 Ų3241 Ų4113%0.12520%0.201CC..Hα-helixtrans-59.6-46.6178.8-175.8-104.6000111.8L324 Y488 I489 Q492 V493 K513 E514 R519 E520 I521L324-Y517 HydrophobicContact CD1-CE1 4.13Å; Y488-Y517 HydrophobicContact CE1-CE1 4.16Å; Y488-Y517 AromaticContact CE1-CZ 3.81Å; Y488-Y517 WeakPolarHBondContact CE1-OH 3.43Å; Y488-Y517 PolarHBondContact OH-OH 3.26Å; I489-Y517 HydrophobicContact CD1-CD1 4.24Å; I489-Y517 HydrophobicContact CG1-CD1 3.92Å; I489-Y517 HydrophobicContact CG1-CE1 4.49Å; I489-Y517 HydrophobicContact CG1-CG 4.16Å; Q492-Y517 HydrophobicContact CB-CD2 3.83Å; Q492-Y517 HydrophobicContact CB-CE2 3.79Å; Q492-Y517 HydrophobicContact CG-CD2 4.27Å; Q492-Y517 HydrophobicContact CG-CE2 3.79Å; V493-Y517 HydrophobicContact CG2-CD2 4.21Å; K513-Y517 WeakPolarHBondContact O-CB 3.26Å; K513-Y517 PolarHBondContact O-N 2.82Å; E514-Y517 PolarHBondContact O-N 3.36Å; Y517-R519 VanDerWaalsContact C-N 3.34Å; Y517-R519 PolarHBondContact O-N 2.88Å; Y517-E520 PolarHBondContact O-N 3.37Å; Y517-I521 HydrophobicContact CD1-CD1 4Å; Y517-I521 HydrophobicContact CE1-CD1 3.44Å; Y517-I521 VanDerWaalsContact CE1-CD1 3.44Å; Y517-I521 HydrophobicContact CE1-CG1 4.48Å; Y517-I521 PolarHBondContact O-N 3.39Å; Y517-I521 VanDerWaalsContact O-N 3.1Å
518Y97.9Very high95.8Very high0 Ų039.5 Ų39.50%021%0.21CC..Hα-helixtrans-64.3-39.5175.7-63.3-15.1000112.1L324 I328 V339 I489 E514 Y516 E520 I521 F522L324-Y518 HydrophobicContact CD2-CE1 3.98Å; I328-Y518 HydrophobicContact CD1-CD1 3.86Å; I328-Y518 HydrophobicContact CD1-CG 4.17Å; V339-Y518 HydrophobicContact CB-CD2 3.86Å; V339-Y518 HydrophobicContact CB-CE2 3.71Å; V339-Y518 HydrophobicContact CB-CG 4.44Å; V339-Y518 HydrophobicContact CG1-CD1 4.08Å; V339-Y518 HydrophobicContact CG1-CD2 3.91Å; V339-Y518 HydrophobicContact CG1-CE1 3.82Å; V339-Y518 HydrophobicContact CG1-CE2 3.6Å; V339-Y518 HydrophobicContact CG1-CG 4.13Å; V339-Y518 HydrophobicContact CG2-CD2 4.12Å; V339-Y518 HydrophobicContact CG2-CE2 4.48Å; V339-Y518 HydrophobicContact CG2-CG 4.44Å; I489-Y518 HydrophobicContact CD1-CE1 4.25Å; E514-Y518 HydrophobicContact CG-CD2 3.93Å; E514-Y518 HydrophobicContact CG-CE1 4.2Å; E514-Y518 HydrophobicContact CG-CE2 3.41Å; E514-Y518 VanDerWaalsContact CG-CE2 3.41Å; E514-Y518 PolarHBondContact O-N 3.34Å; E514-Y518 WeakPolarHBondContact OE1-CE2 3.35Å; E514-Y518 PolarHBondContact OE1-OH 3.4Å; Y516-Y518 PolarHBondContact O-N 3.22Å; Y518-E520 VanDerWaalsContact C-N 3.32Å; Y518-E520 PolarHBondContact O-N 3.35Å; Y518-I521 PolarHBondContact O-N 3.11Å; Y518-F522 WeakPolarHBondContact O-CB 3.3Å; Y518-F522 PolarHBondContact O-N 3.25Å
519R97.8Very high95.8Very high4 Ų438.6 Ų38.62%0.01520%0.204CC..Hα-helixtrans-63.6-38.4175.5-178.757.7176.1-81.8-6.3111.9Y334 Y505 F507 N508 P510 S515 Y516 Y517 F522 E523 S530Y334-R519 HydrophobicContact CD2-CB 4.46Å; Y505-R519 HydrophobicContact CD1-CG 4.09Å; Y505-R519 HydrophobicContact CD2-CG 3.78Å; Y505-R519 HydrophobicContact CE1-CG 4.2Å; Y505-R519 HydrophobicContact CE2-CB 4.4Å; Y505-R519 HydrophobicContact CE2-CG 3.86Å; Y505-R519 HydrophobicContact CG-CG 3.88Å; F507-R519 PolarHBondContact O-NH1 2.82Å; F507-R519 PolarHBondContact O-NH2 3.43Å; N508-R519 PolarHBondContact O-NH1 3.1Å; P510-R519 HydrophobicContact CG-CB 3.92Å; P510-R519 HydrophobicContact CG-CG 4.09Å; S515-R519 WeakPolarHBondContact O-CB 3.29Å; S515-R519 PolarHBondContact O-N 2.87Å; Y516-R519 WeakPolarHBondContact O-CB 3.15Å; Y516-R519 PolarHBondContact O-N 3.05Å; Y517-R519 VanDerWaalsContact C-N 3.34Å; Y517-R519 PolarHBondContact O-N 2.88Å; R519-F522 PolarHBondContact O-N 3.13Å; R519-E523 HydrophobicContact CG-CG 4.3Å; R519-E523 IonicContact CZ-OE1 3.55Å; R519-E523 VanDerWaalsContact CZ-OE1 3.29Å; R519-E523 IonicContact NE-OE1 2.71Å; R519-E523 PolarHBondContact NE-OE1 3.41Å; R519-E523 IonicContact NH2-OE1 3.35Å; R519-E523 PolarHBondContact NH2-OE1 2.92Å; R519-E523 WeakPolarHBondContact O-CB 3.19Å; R519-E523 VanDerWaalsContact O-CG 3.26Å; R519-E523 WeakPolarHBondContact O-CG 3.46Å; R519-E523 PolarHBondContact O-N 3.08Å; R519-S530 PolarHBondContact NH2-OG 3.26Å
520E97.8Very high95.7Very high77 Ų7737.1 Ų37.136%0.3620%0.196SC..Hα-helixtrans-65.6-44.4177.3-177.4164.6-163.500112.4K504 Y516 Y517 Y518 F522 E523 K524K504-E520 IonicContact NZ-OE1 2.66Å; Y516-E520 WeakPolarHBondContact O-CB 3.38Å; Y516-E520 PolarHBondContact O-N 2.77Å; Y517-E520 PolarHBondContact O-N 3.37Å; Y518-E520 VanDerWaalsContact C-N 3.32Å; Y518-E520 PolarHBondContact O-N 3.35Å; E520-F522 VanDerWaalsContact C-N 3.32Å; E520-F522 PolarHBondContact O-N 3.35Å; E520-E523 PolarHBondContact O-N 3.38Å; E520-K524 WeakPolarHBondContact O-CB 3.47Å; E520-K524 PolarHBondContact O-N 3.44Å
521I98.3Very high95.7Very high13 Ų1339.9 Ų39.97%0.06722%0.215CC..Hα-helixtrans-61.6-43.4172.5-64.8172.6000110.6E325 I328 Y517 Y518 K524 H525E325-I521 HydrophobicContact CB-CG2 4.38Å; E325-I521 HydrophobicContact CG-CG2 4.11Å; I328-I521 HydrophobicContact CB-CG2 3.81Å; I328-I521 HydrophobicContact CD1-CB 3.84Å; I328-I521 HydrophobicContact CD1-CD1 3.84Å; I328-I521 HydrophobicContact CD1-CG1 4.44Å; I328-I521 HydrophobicContact CD1-CG2 3.79Å; I328-I521 HydrophobicContact CG1-CG2 4.4Å; I328-I521 HydrophobicContact CG2-CB 4.33Å; I328-I521 HydrophobicContact CG2-CG2 3.75Å; Y517-I521 HydrophobicContact CD1-CD1 4Å; Y517-I521 HydrophobicContact CE1-CD1 3.44Å; Y517-I521 VanDerWaalsContact CE1-CD1 3.44Å; Y517-I521 HydrophobicContact CE1-CG1 4.48Å; Y517-I521 PolarHBondContact O-N 3.39Å; Y517-I521 VanDerWaalsContact O-N 3.1Å; Y518-I521 PolarHBondContact O-N 3.11Å; I521-K524 WeakPolarHBondContact O-CB 3.47Å; I521-K524 PolarHBondContact O-N 3.29Å; I521-H525 PolarHBondContact O-CD2 3.4Å; I521-H525 VanDerWaalsContact O-CD2 3.23Å; I521-H525 PolarHBondContact O-N 3.33Å
522F98.6Very high95.8Very high0 Ų032.2 Ų32.20%018%0.182CC..Hα-helixtrans-60-48.9177.4174.1-88.8000111.7I328 E332 Y334 Y518 R519 E520 K524 H525 Y526 Q529 W532I328-F522 HydrophobicContact CG2-CB 4.04Å; E332-F522 WeakPolarHBondContact O-CE2 3.03Å; Y334-F522 HydrophobicContact CD1-CB 4.2Å; Y334-F522 AromaticContact CD1-CD1 3.65Å; Y334-F522 HydrophobicContact CD1-CD1 3.65Å; Y334-F522 AromaticContact CD1-CD2 3.93Å; Y334-F522 HydrophobicContact CD1-CD2 3.93Å; Y334-F522 AromaticContact CD1-CE1 3.99Å; Y334-F522 HydrophobicContact CD1-CE1 3.99Å; Y334-F522 HydrophobicContact CD1-CE2 4.22Å; Y334-F522 AromaticContact CD1-CG 3.63Å; Y334-F522 HydrophobicContact CD1-CG 3.63Å; Y334-F522 HydrophobicContact CD1-CZ 4.25Å; Y334-F522 HydrophobicContact CE1-CD1 4.18Å; Y334-F522 HydrophobicContact CE1-CE1 4.13Å; Y334-F522 HydrophobicContact CE1-CZ 4.43Å; Y334-F522 HydrophobicContact CG-CB 4.43Å; Y334-F522 HydrophobicContact CG-CG 4.34Å; Y518-F522 WeakPolarHBondContact O-CB 3.3Å; Y518-F522 PolarHBondContact O-N 3.25Å; R519-F522 PolarHBondContact O-N 3.13Å; E520-F522 VanDerWaalsContact C-N 3.32Å; E520-F522 PolarHBondContact O-N 3.35Å; F522-K524 VanDerWaalsContact C-N 3.26Å; F522-K524 PolarHBondContact O-N 3.4Å; F522-H525 PolarHBondContact O-N 3.33Å; F522-H525 VanDerWaalsContact O-N 3.11Å; F522-Y526 AromaticContact CD2-CD2 3.79Å; F522-Y526 HydrophobicContact CD2-CD2 3.79Å; F522-Y526 AromaticContact CE2-CD2 3.7Å; F522-Y526 HydrophobicContact CE2-CD2 3.7Å; F522-Y526 HydrophobicContact CE2-CG 4.16Å; F522-Y526 HydrophobicContact CZ-CD2 4.39Å; F522-Y526 HydrophobicContact CZ-CG 4.42Å; F522-Y526 WeakPolarHBondContact O-CA 3.38Å; F522-Y526 WeakPolarHBondContact O-CB 3.4Å; F522-Y526 PolarHBondContact O-N 3.32Å; F522-Q529 HydrophobicContact CE1-CB 4.43Å; F522-Q529 HydrophobicContact CZ-CB 4.14Å; F522-W532 HydrophobicContact CE2-CE3 4.11Å; F522-W532 HydrophobicContact CE2-CZ3 4.38Å; F522-W532 HydrophobicContact CZ-CE3 4Å; F522-W532 HydrophobicContact CZ-CZ3 4.35Å
523E97.2Very high96Very high32 Ų3231.1 Ų31.115%0.1517%0.174CC..Hα-helixtrans-67.8-25-179.6-67.1-77179.700112.6Y505 R519 E520 H525 S527 G528Y505-E523 HydrophobicContact CD1-CG 4.29Å; Y505-E523 HydrophobicContact CE1-CB 4.41Å; Y505-E523 HydrophobicContact CE1-CG 3.76Å; R519-E523 HydrophobicContact CG-CG 4.3Å; R519-E523 IonicContact CZ-OE1 3.55Å; R519-E523 VanDerWaalsContact CZ-OE1 3.29Å; R519-E523 IonicContact NE-OE1 2.71Å; R519-E523 PolarHBondContact NE-OE1 3.41Å; R519-E523 IonicContact NH2-OE1 3.35Å; R519-E523 PolarHBondContact NH2-OE1 2.92Å; R519-E523 WeakPolarHBondContact O-CB 3.19Å; R519-E523 VanDerWaalsContact O-CG 3.26Å; R519-E523 WeakPolarHBondContact O-CG 3.46Å; R519-E523 PolarHBondContact O-N 3.08Å; E520-E523 PolarHBondContact O-N 3.38Å; E523-H525 VanDerWaalsContact C-N 3.33Å; E523-S527 VanDerWaalsContact O-CA 3.29Å; E523-S527 WeakPolarHBondContact O-CA 3.36Å; E523-S527 WeakPolarHBondContact O-CB 3.39Å; E523-S527 PolarHBondContact O-N 2.81Å; E523-S527 WeakPolarHBondContact OE2-CA 3.41Å; E523-G528 PolarHBondContact OE2-N 3.03Å
524K97.1Very high96.1Very high133 Ų13332.2 Ų32.258%0.57819%0.185SC*.Hα-helixtrans-61.8-39.2170.1179.1-169.9179.6-172.10112E325 E520 I521 F522E325-K524 IonicContact OE1-NZ 2.8Å; E325-K524 PolarHBondContact OE1-NZ 2.88Å; E325-K524 IonicContact OE2-NZ 3.69Å; E325-K524 PolarHBondContact OE2-NZ 3.41Å; E520-K524 WeakPolarHBondContact O-CB 3.47Å; E520-K524 PolarHBondContact O-N 3.44Å; I521-K524 WeakPolarHBondContact O-CB 3.47Å; I521-K524 PolarHBondContact O-N 3.29Å; F522-K524 VanDerWaalsContact C-N 3.26Å; F522-K524 PolarHBondContact O-N 3.4Å
525H96.1Very high96.1Very high58 Ų5835.1 Ų35.127%0.26920%0.199SC..Hα-helixtrans-94.3-31.9-179.1-66-67.6000113.7E325 F329 I521 F522 E523E325-H525 VanDerWaalsContact CG-NE2 3.26Å; E325-H525 WeakPolarHBondContact CG-NE2 3.47Å; E325-H525 IonicContact OE1-CE1 2.74Å; E325-H525 PolarHBondContact OE1-CE1 2.9Å; E325-H525 IonicContact OE1-NE2 3.19Å; E325-H525 PolarHBondContact OE1-NE2 3.2Å; F329-H525 HydrophobicContact CD2-CB 4.23Å; F329-H525 AromaticContact CD2-CG 3.95Å; F329-H525 AromaticContact CD2-ND1 3.76Å; I521-H525 PolarHBondContact O-CD2 3.4Å; I521-H525 VanDerWaalsContact O-CD2 3.23Å; I521-H525 PolarHBondContact O-N 3.33Å; F522-H525 PolarHBondContact O-N 3.33Å; F522-H525 VanDerWaalsContact O-N 3.11Å; E523-H525 VanDerWaalsContact C-N 3.33Å
526Y95.1Very high96Very high4 Ų436.8 Ų36.82%0.01621%0.206CC..SBendtrans-134.152.3-168.3-55.7-58.3000111.2K162 T165 F329 E332 F522 G528 Q529 W532K162-Y526 HydrophobicContact CB-CE1 3.89Å; K162-Y526 WeakPolarHBondContact CE-OH 3.07Å; T165-Y526 HydrophobicContact CG2-CD1 4.1Å; T165-Y526 HydrophobicContact CG2-CE1 4.44Å; F329-Y526 VanDerWaalsContact CD2-OH 3.24Å; F329-Y526 WeakPolarHBondContact CD2-OH 3.43Å; F329-Y526 WeakPolarHBondContact CE2-OH 3.46Å; F329-Y526 PolarHBondContact O-OH 2.84Å; E332-Y526 HydrophobicContact CB-CE2 4.19Å; E332-Y526 HydrophobicContact CG-CE2 4.02Å; F522-Y526 AromaticContact CD2-CD2 3.79Å; F522-Y526 HydrophobicContact CD2-CD2 3.79Å; F522-Y526 AromaticContact CE2-CD2 3.7Å; F522-Y526 HydrophobicContact CE2-CD2 3.7Å; F522-Y526 HydrophobicContact CE2-CG 4.16Å; F522-Y526 HydrophobicContact CZ-CD2 4.39Å; F522-Y526 HydrophobicContact CZ-CG 4.42Å; F522-Y526 WeakPolarHBondContact O-CA 3.38Å; F522-Y526 WeakPolarHBondContact O-CB 3.4Å; F522-Y526 PolarHBondContact O-N 3.32Å; Y526-G528 PolarHBondContact O-N 3.09Å; Y526-Q529 VanDerWaalsContact O-CB 3.29Å; Y526-Q529 WeakPolarHBondContact O-CB 3.17Å; Y526-Q529 PolarHBondContact O-N 3.37Å; Y526-W532 AromaticContact CD1-CH2 3.75Å; Y526-W532 HydrophobicContact CD1-CH2 3.75Å; Y526-W532 AromaticContact CD1-CZ3 3.73Å; Y526-W532 HydrophobicContact CD1-CZ3 3.73Å; Y526-W532 HydrophobicContact CD2-CZ3 4.21Å; Y526-W532 HydrophobicContact CE1-CH2 4.42Å; Y526-W532 HydrophobicContact CE1-CZ3 4.31Å; Y526-W532 HydrophobicContact CG-CH2 4.09Å; Y526-W532 AromaticContact CG-CZ3 3.68Å; Y526-W532 HydrophobicContact CG-CZ3 3.68Å
527S93.2Very high95.8Very high93 Ų9337.6 Ų37.665%0.6521%0.209SC*.THydrogen-bonded Turntrans-52124-176.7-169.80000112.1E523 Q529E523-S527 VanDerWaalsContact O-CA 3.29Å; E523-S527 WeakPolarHBondContact O-CA 3.36Å; E523-S527 WeakPolarHBondContact O-CB 3.39Å; E523-S527 PolarHBondContact O-N 2.81Å; E523-S527 WeakPolarHBondContact OE2-CA 3.41Å; S527-Q529 VanDerWaalsContact C-N 3.27Å; S527-Q529 PolarHBondContact O-N 3.27Å
528G90.2Very high95.5Very high55 Ų5539 Ų3957%0.56722%0.218SC*.THydrogen-bonded Turntrans78.12.9178.500000115.2E523 Y526E523-G528 PolarHBondContact OE2-N 3.03Å; Y526-G528 PolarHBondContact O-N 3.09Å
529Q94.1Very high95.1Very high19 Ų1939.7 Ų39.79%0.08922%0.222CC..  trans-96.915.7-174.9-57.8-61.9-23.800113.9F522 Y526 S527 S531 W532F522-Q529 HydrophobicContact CE1-CB 4.43Å; F522-Q529 HydrophobicContact CZ-CB 4.14Å; Y526-Q529 VanDerWaalsContact O-CB 3.29Å; Y526-Q529 WeakPolarHBondContact O-CB 3.17Å; Y526-Q529 PolarHBondContact O-N 3.37Å; S527-Q529 VanDerWaalsContact C-N 3.27Å; S527-Q529 PolarHBondContact O-N 3.27Å; Q529-S531 PolarHBondContact O-N 2.59Å; Q529-W532 HydrophobicContact CB-CD2 3.86Å; Q529-W532 HydrophobicContact CB-CE3 4.06Å; Q529-W532 HydrophobicContact CB-CH2 3.71Å; Q529-W532 HydrophobicContact CB-CZ2 3.49Å; Q529-W532 VanDerWaalsContact CB-CZ2 3.49Å; Q529-W532 HydrophobicContact CB-CZ3 3.98Å; Q529-W532 HydrophobicContact CG-CH2 3.75Å; Q529-W532 HydrophobicContact CG-CZ2 3.48Å; Q529-W532 VanDerWaalsContact CG-CZ2 3.48Å; Q529-W532 HydrophobicContact CG-CZ3 4.49Å; Q529-W532 VanDerWaalsContact O-CG 3.31Å; Q529-W532 PolarHBondContact O-N 2.95Å; Q529-W532 VanDerWaalsContact O-N 3.1Å
530S94Very high94.8Very high12 Ų1244.4 Ų44.48%0.08424%0.239CC..G310 helixtrans-58.8-21.1-175.857.30000114.8Y334 F507 R519 W532 L533Y334-S530 PolarHBondContact OH-O 3.25Å; Y334-S530 VanDerWaalsContact OH-O 3.08Å; F507-S530 WeakPolarHBondContact CE1-O 3.41Å; R519-S530 PolarHBondContact NH2-OG 3.26Å; S530-W532 PolarHBondContact O-N 3.04Å; S530-L533 PolarHBondContact O-N 2.88Å
531S94.9Very high94.6Very high64 Ų6444.2 Ų44.245%0.44824%0.235SC..G310 helixtrans-66.8-10.6176.8630000114.9Q529 L533Q529-S531 PolarHBondContact O-N 2.59Å; S531-L533 PolarHBondContact O-N 3.44Å
532W96.4Very high93.9Very high12 Ų1245.1 Ų45.15%0.04524%0.24CC..G310 helixtrans-61.8-28.6170.6-62.9-12.9000112.7A161 T165 V177 E332 F522 Y526 Q529 S530 P534A161-W532 HydrophobicContact CB-CD2 4.23Å; A161-W532 HydrophobicContact CB-CE3 4.03Å; A161-W532 HydrophobicContact CB-CH2 3.36Å; A161-W532 HydrophobicContact CB-CZ2 3.56Å; A161-W532 HydrophobicContact CB-CZ3 3.61Å; T165-W532 HydrophobicContact CG2-CH2 3.77Å; T165-W532 HydrophobicContact CG2-CZ2 4.21Å; V177-W532 HydrophobicContact CB-CZ2 3.81Å; V177-W532 HydrophobicContact CG1-CZ2 3.94Å; V177-W532 HydrophobicContact CG2-CZ2 4.32Å; V177-W532 PolarHBondContact O-NE1 3.44Å; E332-W532 HydrophobicContact CB-CE3 4.09Å; E332-W532 HydrophobicContact CB-CZ3 4Å; F522-W532 HydrophobicContact CE2-CE3 4.11Å; F522-W532 HydrophobicContact CE2-CZ3 4.38Å; F522-W532 HydrophobicContact CZ-CE3 4Å; F522-W532 HydrophobicContact CZ-CZ3 4.35Å; Y526-W532 AromaticContact CD1-CH2 3.75Å; Y526-W532 HydrophobicContact CD1-CH2 3.75Å; Y526-W532 AromaticContact CD1-CZ3 3.73Å; Y526-W532 HydrophobicContact CD1-CZ3 3.73Å; Y526-W532 HydrophobicContact CD2-CZ3 4.21Å; Y526-W532 HydrophobicContact CE1-CH2 4.42Å; Y526-W532 HydrophobicContact CE1-CZ3 4.31Å; Y526-W532 HydrophobicContact CG-CH2 4.09Å; Y526-W532 AromaticContact CG-CZ3 3.68Å; Y526-W532 HydrophobicContact CG-CZ3 3.68Å; Q529-W532 HydrophobicContact CB-CD2 3.86Å; Q529-W532 HydrophobicContact CB-CE3 4.06Å; Q529-W532 HydrophobicContact CB-CH2 3.71Å; Q529-W532 HydrophobicContact CB-CZ2 3.49Å; Q529-W532 VanDerWaalsContact CB-CZ2 3.49Å; Q529-W532 HydrophobicContact CB-CZ3 3.98Å; Q529-W532 HydrophobicContact CG-CH2 3.75Å; Q529-W532 HydrophobicContact CG-CZ2 3.48Å; Q529-W532 VanDerWaalsContact CG-CZ2 3.48Å; Q529-W532 HydrophobicContact CG-CZ3 4.49Å; Q529-W532 VanDerWaalsContact O-CG 3.31Å; Q529-W532 PolarHBondContact O-N 2.95Å; Q529-W532 VanDerWaalsContact O-N 3.1Å; S530-W532 PolarHBondContact O-N 3.04Å; W532-P534 WeakPolarHBondContact O-CD 3.25Å
533L97.2Very high93.1Very high3 Ų354.8 Ų54.82%0.01629%0.285CS..SBendtrans-104.4105.7170.6-177.967.8000108.9Y334 D335 F400 F507 N508 S530 S531 H535 F536Y334-L533 HydrophobicContact CD2-CD2 4.09Å; Y334-L533 HydrophobicContact CE1-CB 4.03Å; Y334-L533 HydrophobicContact CE1-CD2 4.27Å; Y334-L533 HydrophobicContact CE2-CD2 3.81Å; Y334-L533 HydrophobicContact CG-CD2 4.45Å; D335-L533 HydrophobicContact CB-CD1 4.41Å; D335-L533 HydrophobicContact CB-CD2 3.83Å; F400-L533 HydrophobicContact CE1-CD1 3.88Å; F400-L533 HydrophobicContact CZ-CD1 4.4Å; F507-L533 WeakPolarHBondContact CE1-O 3.41Å; N508-L533 PolarHBondContact ND2-O 2.78Å; S530-L533 PolarHBondContact O-N 2.88Å; S531-L533 PolarHBondContact O-N 3.44Å; L533-H535 VanDerWaalsContact C-N 3.35Å; L533-H535 WeakPolarHBondContact CD1-O 3.5Å; L533-H535 WeakPolarHBondContact CG-O 3.33Å; L533-H535 PolarHBondContact O-N 3.07Å; L533-F536 HydrophobicContact CD2-CD1 4.4Å
534P96.3Very high92.2Very high59 Ų5954.4 Ų54.438%0.38329%0.288SS..  trans-69.8-31.3-179.725.6-32.9000112.9L399 N508 W532L399-P534 HydrophobicContact CD1-CG 3.74Å; N508-P534 PolarHBondContact ND2-O 3.43Å; N508-P534 PolarHBondContact OD1-O 2.93Å; W532-P534 WeakPolarHBondContact O-CD 3.25Å
535H95.2Very high91Very high61 Ų6153.7 Ų53.728%0.28230%0.295SS..SBendtrans-156.9156.818054-89.2000111.4E396 F400 N508 L533E396-H535 VanDerWaalsContact CD-NE2 3.29Å; E396-H535 IonicContact OE1-CE1 2.66Å; E396-H535 IonicContact OE1-NE2 2.65Å; E396-H535 IonicContact OE2-CD2 2.68Å; E396-H535 IonicContact OE2-CE1 3.88Å; E396-H535 PolarHBondContact OE2-CE1 2.85Å; E396-H535 IonicContact OE2-NE2 3.93Å; E396-H535 PolarHBondContact OE2-NE2 3.23Å; F400-H535 AromaticContact CE2-NE2 3.95Å; F400-H535 AromaticContact CZ-CD2 3.88Å; F400-H535 AromaticContact CZ-NE2 3.85Å; N508-H535 PolarHBondContact ND2-N 2.58Å; L533-H535 VanDerWaalsContact C-N 3.35Å; L533-H535 WeakPolarHBondContact CD1-O 3.5Å; L533-H535 WeakPolarHBondContact CG-O 3.33Å; L533-H535 PolarHBondContact O-N 3.07Å
536F94.4Very high90.1Very high38 Ų3851.4 Ų51.417%0.16729%0.285CS..  trans-70.7145.7169-71-80.6000110.9Y334 D335 N508 L533 M538Y334-F536 AromaticContact CD2-CE1 3.77Å; Y334-F536 HydrophobicContact CD2-CE1 3.77Å; Y334-F536 AromaticContact CD2-CZ 3.66Å; Y334-F536 HydrophobicContact CD2-CZ 3.66Å; Y334-F536 HydrophobicContact CE2-CE1 4.01Å; Y334-F536 HydrophobicContact CE2-CE2 4.2Å; Y334-F536 AromaticContact CE2-CZ 3.57Å; Y334-F536 HydrophobicContact CE2-CZ 3.57Å; D335-F536 WeakPolarHBondContact OD1-CA 3.09Å; N508-F536 HydrophobicContact CB-CE2 4.2Å; L533-F536 HydrophobicContact CD2-CD1 4.4Å; F536-M538 HydrophobicContact CB-CG 4.49Å; F536-M538 PolarHBondContact O-N 3.04Å
537W93.2Very high89Confident20 Ų2051.7 Ų51.78%0.07629%0.287CS..  trans-64.6126170-171.896.4000109.1D335 T337 Y374 Y376 F400 P547D335-W537 PolarHBondContact OD1-N 2.81Å; T337-W537 HydrophobicContact CG2-CE3 4.31Å; Y374-W537 HydrophobicContact CD1-CZ2 4.36Å; Y374-W537 HydrophobicContact CD2-CZ2 4.23Å; Y374-W537 HydrophobicContact CE1-CZ2 4.23Å; Y374-W537 HydrophobicContact CE2-CZ2 4.12Å; Y374-W537 HydrophobicContact CG-CZ2 4.37Å; Y376-W537 HydrophobicContact CE1-CH2 4.35Å; Y376-W537 HydrophobicContact CE1-CZ2 4.32Å; F400-W537 HydrophobicContact CD1-CB 3.74Å; F400-W537 HydrophobicContact CD1-CG 4.39Å; F400-W537 AromaticContact CD2-CD1 3.7Å; F400-W537 HydrophobicContact CE1-CB 3.58Å; F400-W537 HydrophobicContact CE2-CB 4.38Å; F400-W537 HydrophobicContact CG-CB 4.22Å; F400-W537 AromaticContact CG-CD1 3.79Å; F400-W537 HydrophobicContact CG-CG 4.39Å; F400-W537 HydrophobicContact CZ-CB 3.92Å; W537-P547 HydrophobicContact CE3-CB 3.66Å; W537-P547 HydrophobicContact CZ3-CB 4Å; W537-P547 VanDerWaalsContact O-CB 3.29Å; W537-P547 WeakPolarHBondContact O-CB 3.33Å
538M90.8Very high87.7Confident63 Ų6347.7 Ų47.731%0.3126%0.259SS..  trans-142.1140.4179.5-66.7-60.5-64.200110.8F536 A544 P547F536-M538 HydrophobicContact CB-CG 4.49Å; F536-M538 PolarHBondContact O-N 3.04Å; M538-A544 HydrophobicContact CE-CB 4.08Å; M538-A544 WeakPolarHBondContact CE-O 3.5Å; M538-P547 HydrophobicContact SD-CB 4.04Å
539P90.2Very high86.3Confident13 Ų1346 Ų468%0.08424%0.24CC..  trans-68.1142.8175.728.9-34.7000111.3Y376 A544Y376-P539 HydrophobicContact CD1-CB 3.65Å; Y376-P539 HydrophobicContact CD2-CB 4.35Å; Y376-P539 HydrophobicContact CE1-CB 4.21Å; Y376-P539 HydrophobicContact CG-CB 3.73Å; P539-A544 HydrophobicContact CG-CB 4.14Å
540R90.7Very high84.7Confident103 Ų10349 Ų4939%0.38925%0.25SC..SBendtrans-81.4162.6171.6-75.5-161.3175179.1-5.9112.3Y376 E389 I542Y376-R540 HydrophobicContact CD2-CB 4.16Å; Y376-R540 WeakPolarHBondContact CD2-O 3.34Å; Y376-R540 HydrophobicContact CE2-CB 3.93Å; E389-R540 WeakPolarHBondContact OE2-CD 3.15Å; E389-R540 IonicContact OE2-CZ 2.71Å; E389-R540 IonicContact OE2-NE 3.71Å; E389-R540 PolarHBondContact OE2-NE 3.21Å; E389-R540 IonicContact OE2-NH1 3.58Å; R540-I542 PolarHBondContact O-N 3.48Å
541W92.6Very high82.8Confident73 Ų7351.9 Ų51.928%0.27727%0.267SS..SBendtrans59.913.7175.4-42.3-64.6000115.1Y376 F377 K379 A380 P381 E385 E389Y376-W541 AromaticContact CD2-CE3 3.7Å; Y376-W541 HydrophobicContact CD2-CE3 3.7Å; Y376-W541 AromaticContact CD2-CZ3 3.72Å; Y376-W541 HydrophobicContact CD2-CZ3 3.72Å; Y376-W541 HydrophobicContact CE2-CE3 4.23Å; Y376-W541 AromaticContact CE2-CZ3 3.89Å; Y376-W541 HydrophobicContact CE2-CZ3 3.89Å; F377-W541 HydrophobicContact CD1-CH2 4.21Å; F377-W541 HydrophobicContact CD1-CZ3 4.06Å; F377-W541 HydrophobicContact CE1-CH2 4.34Å; F377-W541 HydrophobicContact CE1-CZ3 4.49Å; K379-W541 HydrophobicContact CB-CB 4.3Å; A380-W541 HydrophobicContact CB-CE3 4.08Å; A380-W541 HydrophobicContact CB-CH2 3.53Å; A380-W541 HydrophobicContact CB-CZ2 4.03Å; A380-W541 HydrophobicContact CB-CZ3 3.56Å; P381-W541 VanDerWaalsContact CD-CE2 3.43Å; P381-W541 HydrophobicContact CG-CG 4.43Å; E385-W541 HydrophobicContact CB-CZ2 4.06Å; E385-W541 PolarHBondContact OE2-NE1 3.26Å; E389-W541 HydrophobicContact CB-CH2 3.79Å; E389-W541 HydrophobicContact CB-CZ2 4.18Å; E389-W541 HydrophobicContact CG-CH2 4.01Å
542I84.9Confident81Confident32 Ų3249.5 Ų49.516%0.16425%0.25CC..SBendtrans-135.1130.2176.1-49.4175.8000108.9K379 R540 A544 L552K379-I542 HydrophobicContact CD-CD1 3.84Å; K379-I542 HydrophobicContact CD-CG1 3.61Å; R540-I542 PolarHBondContact O-N 3.48Å; I542-A544 PolarHBondContact O-N 3.41Å; I542-A544 VanDerWaalsContact O-N 3.1Å; I542-L552 HydrophobicContact CB-CD2 4.21Å; I542-L552 HydrophobicContact CD1-CD1 3.7Å; I542-L552 HydrophobicContact CD1-CD2 3.8Å; I542-L552 HydrophobicContact CD1-CG 4.32Å; I542-L552 HydrophobicContact CG2-CD2 3.41Å; I542-L552 VanDerWaalsContact CG2-CD2 3.41Å
543E80.8Confident78.7Confident203 Ų20358 Ų5895%0.94929%0.287SS*.  trans-70.5102.1166.5-66.2-176.817300108.9
544A78.4Confident76.3Confident25 Ų2563.2 Ų63.221%0.20731%0.311CS..  trans-129.6137.6177.100000109.7M538 P539 I542 L552M538-A544 HydrophobicContact CE-CB 4.08Å; M538-A544 WeakPolarHBondContact CE-O 3.5Å; P539-A544 HydrophobicContact CG-CB 4.14Å; I542-A544 PolarHBondContact O-N 3.41Å; I542-A544 VanDerWaalsContact O-N 3.1Å; A544-L552 HydrophobicContact CB-CD2 4.47Å
545T73.2Confident73.9Confident117 Ų11763.3 Ų63.372%0.71830%0.304SS*.SBendtrans-98-17171.7510000112.3
546D76.5Confident71.3Confident11 Ų1167.9 Ų67.96%0.05932%0.323CS..SBendtrans-124.5140.3173.8-174.2-88.2000108.9R340 S548 T551R340-D546 IonicContact CZ-OD1 3.14Å; R340-D546 IonicContact CZ-OD2 3.31Å; R340-D546 IonicContact NH1-OD1 2.68Å; R340-D546 PolarHBondContact NH1-OD1 3.02Å; R340-D546 IonicContact NH1-OD2 3.62Å; R340-D546 IonicContact NH2-OD1 3.49Å; R340-D546 PolarHBondContact NH2-OD1 3.13Å; R340-D546 IonicContact NH2-OD2 3.6Å; R340-D546 PolarHBondContact NH2-OD2 3.03Å; D546-S548 VanDerWaalsContact C-N 3.25Å; D546-S548 PolarHBondContact O-N 2.66Å; D546-S548 WeakPolarHBondContact OD1-CA 3.34Å; D546-S548 WeakPolarHBondContact OD1-CB 3.47Å; D546-S548 PolarHBondContact OD1-N 2.87Å; D546-T551 HydrophobicContact CB-CG2 4.05Å
547P72.3Confident68.4Low9 Ų969.5 Ų69.56%0.05834%0.339CS..  trans-75.6-7.9-178.329.4-35.5000114.9I336 T337 W537 M538 A549I336-P547 HydrophobicContact CB-CG 3.99Å; I336-P547 HydrophobicContact CD1-CG 4.49Å; I336-P547 HydrophobicContact CG2-CG 4.09Å; T337-P547 WeakPolarHBondContact OG1-CB 3.43Å; T337-P547 WeakPolarHBondContact OG1-CG 3.24Å; W537-P547 HydrophobicContact CE3-CB 3.66Å; W537-P547 HydrophobicContact CZ3-CB 4Å; W537-P547 VanDerWaalsContact O-CB 3.29Å; W537-P547 WeakPolarHBondContact O-CB 3.33Å; M538-P547 HydrophobicContact SD-CB 4.04Å; P547-A549 PolarHBondContact O-N 3.17Å
548S66.6Low65.5Low9 Ų972.7 Ų72.76%0.06337%0.37CS..  trans-65.2131.1177.9179.30000111.5D546 R550 T551D546-S548 VanDerWaalsContact C-N 3.25Å; D546-S548 PolarHBondContact O-N 2.66Å; D546-S548 WeakPolarHBondContact OD1-CA 3.34Å; D546-S548 WeakPolarHBondContact OD1-CB 3.47Å; D546-S548 PolarHBondContact OD1-N 2.87Å; S548-R550 PolarHBondContact O-N 3.35Å; S548-R550 VanDerWaalsContact O-N 3.12Å; S548-R550 WeakPolarHBondContact OG-CB 3.5Å; S548-R550 WeakPolarHBondContact OG-CG 3.33Å; S548-R550 PolarHBondContact OG-N 3.07Å; S548-R550 VanDerWaalsContact OG-N 3.07Å; S548-T551 PolarHBondContact O-N 2.79Å; S548-T551 VanDerWaalsContact O-N 3.15Å; S548-T551 PolarHBondContact O-OG1 3.07Å
549A59.5Low62.6Low20 Ų2073.8 Ų73.817%0.16539%0.389CS..G310 helixtrans-60.2-20171.300000113P547 T551 L552 Y555P547-A549 PolarHBondContact O-N 3.17Å; A549-T551 PolarHBondContact O-N 3.13Å; A549-L552 HydrophobicContact CB-CD1 4.23Å; A549-L552 VanDerWaalsContact O-CB 3.24Å; A549-L552 WeakPolarHBondContact O-CB 3.37Å; A549-L552 WeakPolarHBondContact O-CG 3.34Å; A549-L552 PolarHBondContact O-N 3.43Å; A549-Y555 HydrophobicContact CB-CD2 3.65Å; A549-Y555 HydrophobicContact CB-CE2 3.35Å; A549-Y555 WeakPolarHBondContact O-CD2 3.41Å
550R60.2Low59.4Low81 Ų8181.3 Ų81.331%0.30642%0.423SS..G310 helixtrans-64.3-24.3176.1-64.5-175.5179.3-120.3-5.8113.7D472 S480 S548D472-R550 PolarHBondContact O-NH2 3.1Å; D472-R550 WeakPolarHBondContact OD1-CD 3.48Å; D472-R550 IonicContact OD1-CZ 2.81Å; D472-R550 IonicContact OD1-NE 2.62Å; D472-R550 PolarHBondContact OD1-NE 3.48Å; D472-R550 IonicContact OD1-NH2 2.63Å; S480-R550 PolarHBondContact OG-NH1 2.82Å; S548-R550 PolarHBondContact O-N 3.35Å; S548-R550 VanDerWaalsContact O-N 3.12Å; S548-R550 WeakPolarHBondContact OG-CB 3.5Å; S548-R550 WeakPolarHBondContact OG-CG 3.33Å; S548-R550 PolarHBondContact OG-N 3.07Å; S548-R550 VanDerWaalsContact OG-N 3.07Å
551T53.9Low56.4Low73 Ų7388.5 Ų88.545%0.44846%0.461SS..G310 helixtrans-79.5-11.3176.166.40000112.4D546 S548 A549D546-T551 HydrophobicContact CB-CG2 4.05Å; S548-T551 PolarHBondContact O-N 2.79Å; S548-T551 VanDerWaalsContact O-N 3.15Å; S548-T551 PolarHBondContact O-OG1 3.07Å; A549-T551 PolarHBondContact O-N 3.13Å
552L57.2Low54.5Low15 Ų1589.3 Ų89.38%0.07947%0.47CS..SBendtrans-83.6130.4-177.9-52.1179.1000111.1I542 A544 A549 H554 Y555I542-L552 HydrophobicContact CB-CD2 4.21Å; I542-L552 HydrophobicContact CD1-CD1 3.7Å; I542-L552 HydrophobicContact CD1-CD2 3.8Å; I542-L552 HydrophobicContact CD1-CG 4.32Å; I542-L552 HydrophobicContact CG2-CD2 3.41Å; I542-L552 VanDerWaalsContact CG2-CD2 3.41Å; A544-L552 HydrophobicContact CB-CD2 4.47Å; A549-L552 HydrophobicContact CB-CD1 4.23Å; A549-L552 VanDerWaalsContact O-CB 3.24Å; A549-L552 WeakPolarHBondContact O-CB 3.37Å; A549-L552 WeakPolarHBondContact O-CG 3.34Å; A549-L552 PolarHBondContact O-N 3.43Å; L552-H554 PolarHBondContact O-N 2.73Å; L552-Y555 PolarHBondContact O-N 2.78Å
553K48.2Very low53Low189 Ų18992.3 Ų92.382%0.82249%0.486SS*.G310 helixtrans-53.8-30.5-178.1-69.8-178.3-179.5176.20114.5Y555 K556K553-Y555 PolarHBondContact O-N 3.04Å; K553-K556 PolarHBondContact O-N 3.23Å
554H47.3Very low51.4Low113 Ų11386.1 Ų86.152%0.52346%0.46SS..G310 helixtrans-72.3-20.6179.7-80.2-56.1000114.8K379 L552 K556 S557K379-H554 VanDerWaalsContact CE-CD2 3.49Å; K379-H554 WeakPolarHBondContact CE-CD2 3.25Å; L552-H554 PolarHBondContact O-N 2.73Å; H554-K556 PolarHBondContact O-N 3.39Å; H554-S557 PolarHBondContact O-N 3.02Å; H554-S557 PolarHBondContact O-OG 3.13Å
555Y47Very low49.8Very low61 Ų6189.7 Ų89.724%0.23948%0.475CS..G310 helixtrans-68.8-24.8173.7-118.1-86.6000111.8I375 K467 A549 L552 K553I375-Y555 HydrophobicContact CG1-CE2 4.06Å; K467-Y555 PolarHBondContact O-OH 3.5Å; A549-Y555 HydrophobicContact CB-CD2 3.65Å; A549-Y555 HydrophobicContact CB-CE2 3.35Å; A549-Y555 WeakPolarHBondContact O-CD2 3.41Å; L552-Y555 PolarHBondContact O-N 2.78Å; K553-Y555 PolarHBondContact O-N 3.04Å
556K39.6Very low48.4Very low158 Ų15888 Ų8869%0.68746%0.46SS*.THydrogen-bonded Turntrans-74.5-27.4179-70.5-172.8176.5-177.20113.5K553 H554K553-K556 PolarHBondContact O-N 3.23Å; H554-K556 PolarHBondContact O-N 3.39Å
557S32.8Very low46.5Very low71 Ų7193.1 Ų93.150%0.49749%0.487SS..THydrogen-bonded Turntrans-79-26.7-177.748.30000113.7H554H554-S557 PolarHBondContact O-N 3.02Å; H554-S557 PolarHBondContact O-OG 3.13Å
558A33.7Very low44.6Very low87 Ų8799.1 Ų99.172%0.71952%0.517SS*.THydrogen-bonded Turntrans-84.1-13179.500000113.9
559A28.7Very low42.9Very low86 Ų86106.1 Ų106.171%0.71155%0.552SS**THydrogen-bonded Turntrans-98.15.9-179.800000113.5
560Q24.1Very low41.6Very low172 Ų172113.3 Ų113.380%0.80459%0.585SS**  trans-127.213-176.7-77.5-167.6-25.100114.8
561E26.2Very low39.9Very low253 Ų253116.2 Ų116.2100%1.18261%0.61SS**  trans-116.80169.6-73.4-172.7169.100112.3

Retrieved 561 of 561 residues in 435.3 ms (Link to these results)