A0A096LNN5_HUMAN Loading...

Aquaporin 7

AlphaFold DB , UniProt , Accession A0A096LNN5, Species HUMAN (Homo sapiens, Human), Gene AQP7, Length 41 aa.

						>A0A096LNN5_HUMAN|A0A096LNN5|AQP7
MVQASGHRRGLLAPWIALSAPHPPICKVASLVCHFYWSSPN
					

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	45.5	Very low	51.8	Low	244 Å²	244	148.2 Å²	148.2	100%	1.202	81%	0.814	S	S	*	*				0	114	0	-62.5	170.2	-172.1	0	0	105.3
2	V	41.7	Very low	52	Low	144 Å²	144	146.5 Å²	146.5	87%	0.873	80%	0.802	S	S	*	*			cis	-133.9	131.6	41.2	174.4	0	0	0	0	109.4
3	Q	44.1	Very low	52.2	Low	181 Å²	181	141.8 Å²	141.8	85%	0.846	80%	0.795	S	S	*	*			trans	-82.9	112.2	177.7	177.1	172.9	-22.8	0	0	109
4	A	55.8	Low	52	Low	86 Å²	86	137.9 Å²	137.9	71%	0.711	78%	0.778	S	S	*	*	P	Polyproline II helix	trans	-75.9	119.8	169	0	0	0	0	0	109.3
5	S	49.1	Very low	51.7	Low	116 Å²	116	140.8 Å²	140.8	81%	0.811	77%	0.772	S	S	*	*	P	Polyproline II helix	trans	-51.6	138.3	-176.4	-73.7	0	0	0	0	113.8
6	G	63.3	Low	51.8	Low	74 Å²	74	140.3 Å²	140.3	76%	0.763	77%	0.767	S	S	*	*	P	Polyproline II helix	trans	-66.7	142.5	170.8	0	0	0	0	0	112.2
7	H	51.1	Low	51.8	Low	157 Å²	157	136.1 Å²	136.1	73%	0.727	76%	0.755	S	S	*	*	S	Bend	trans	-155	-32.2	149.7	-165.6	57.3	0	0	0	115
8	R	55.8	Low	51.7	Low	170 Å²	170	136.4 Å²	136.4	64%	0.642	75%	0.754	S	S	*	*			trans	-150.3	54.4	-176.5	-63.9	-171.9	-172.5	-173	2.3	115.6	G10	R8-G10 PolarHBondContact O-N 3.04Å
9	R	54.9	Low	51.8	Low	253 Å²	253	133.8 Å²	133.8	96%	0.955	75%	0.747	S	S	*	*	T	Hydrogen-bonded Turn	trans	-76.9	14.2	173.7	-81.1	-176.4	170.6	175.3	-3.1	114.7
10	G	54.8	Low	52.1	Low	70 Å²	70	130.2 Å²	130.2	72%	0.722	73%	0.734	S	S	*	*	T	Hydrogen-bonded Turn	trans	-146	10.1	-171.8	0	0	0	0	0	118.7	R8	R8-G10 PolarHBondContact O-N 3.04Å
11	L	53.4	Low	52.3	Low	135 Å²	135	130 Å²	130	71%	0.707	74%	0.739	S	S	*	*	S	Bend	trans	-129.1	7.6	-179.2	-74.2	173.4	0	0	0	114.9
12	L	54.8	Low	52.8	Low	128 Å²	128	124.7 Å²	124.7	67%	0.67	71%	0.711	S	S	*	*	S	Bend	trans	-116.1	20.5	-173.7	-72	172.8	0	0	0	114.4
13	A	55	Low	53.6	Low	85 Å²	85	121.5 Å²	121.5	70%	0.702	69%	0.693	S	S	*	*	S	Bend	trans	-147.5	78.9	172.4	0	0	0	0	0	109.8
14	P	48.2	Very low	54.4	Low	87 Å²	87	117.7 Å²	117.7	57%	0.565	68%	0.684	S	S	*	*	S	Bend		-133.9	15.5	110	38.1	-27.8	0	0	0	113.5	I16 A17	P14-I16 PolarHBondContact O-N 2.71Å; P14-I16 VanDerWaalsContact O-N 3.13Å; P14-A17 PolarHBondContact O-N 2.95Å
15	W	48.8	Very low	54.7	Low	182 Å²	182	119.7 Å²	119.7	69%	0.689	68%	0.681	S	S	*	*	T	Hydrogen-bonded Turn	trans	-64.9	-12.4	175.7	-72.7	92	0	0	0	114.2
16	I	52.6	Low	55.4	Low	133 Å²	133	116.9 Å²	116.9	68%	0.682	66%	0.661	S	S	*	*	T	Hydrogen-bonded Turn	trans	-88.4	-17.9	174.8	-53.5	172.7	0	0	0	110.8	P14 S19	P14-I16 PolarHBondContact O-N 2.71Å; P14-I16 VanDerWaalsContact O-N 3.13Å; I16-S19 PolarHBondContact O-OG 3.44Å
17	A	51.2	Low	55.7	Low	69 Å²	69	121 Å²	121	57%	0.57	66%	0.658	S	S	*	*	G	3₁₀ helix	trans	-85.3	-13.9	174.1	0	0	0	0	0	113	P14 S19 A20	P14-A17 PolarHBondContact O-N 2.95Å; A17-S19 PolarHBondContact O-N 3.35Å; A17-A20 WeakPolarHBondContact O-CB 3.15Å; A17-A20 PolarHBondContact O-N 2.94Å
18	L	50.4	Low	57	Low	141 Å²	141	117.8 Å²	117.8	74%	0.738	65%	0.649	S	S	*	*	G	3₁₀ helix	trans	-70.7	-14.7	167.5	-104.8	86.7	0	0	0	113	A20	L18-A20 VanDerWaalsContact C-N 3.33Å
19	S	53.2	Low	57.9	Low	88 Å²	88	112.5 Å²	112.5	62%	0.615	64%	0.642	S	S	*	*	G	3₁₀ helix	trans	-96.1	24.3	169.8	43.6	0	0	0	0	112.5	I16 A17	I16-S19 PolarHBondContact O-OG 3.44Å; A17-S19 PolarHBondContact O-N 3.35Å
20	A	57.7	Low	58.9	Low	60 Å²	60	103.4 Å²	103.4	50%	0.496	62%	0.617	S	S	.	*	S	Bend	trans	-63.1	134.3	162.2	0	0	0	0	0	108.7	A17 L18 H22	A17-A20 WeakPolarHBondContact O-CB 3.15Å; A17-A20 PolarHBondContact O-N 2.94Å; L18-A20 VanDerWaalsContact C-N 3.33Å; A20-H22 PolarHBondContact O-N 3.41Å
21	P	57.7	Low	60.1	Low	127 Å²	127	105.9 Å²	105.9	83%	0.825	61%	0.613	S	S	*	*			trans	-60.6	107.2	-177.4	23.2	-31.8	0	0	0	109.5
22	H	54.6	Low	61.5	Low	133 Å²	133	104 Å²	104	62%	0.616	61%	0.607	S	S	*	*			trans	-64.5	139.4	177.6	-125.6	-123.9	0	0	0	109.4	A20 C26	A20-H22 PolarHBondContact O-N 3.41Å; H22-C26 HydrophobicContact CB-CB 3.65Å; H22-C26 WeakPolarHBondContact CB-SG 3.23Å; H22-C26 PolarHBondContact ND1-SG 3.49Å
23	P	58.5	Low	62.8	Low	77 Å²	77	102.1 Å²	102.1	50%	0.5	60%	0.603	S	S	.	*			trans	-54.1	162.3	179.4	22	-32.2	0	0	0	111.6	I25 C26	P23-I25 PolarHBondContact O-N 3.35Å; P23-C26 PolarHBondContact O-N 2.96Å
24	P	60.9	Low	63.7	Low	101 Å²	101	103.9 Å²	103.9	66%	0.656	60%	0.597	S	S	*	*	T	Hydrogen-bonded Turn	trans	-41.2	-23.4	-166.6	12.3	-32.2	0	0	0	117.8	C26 K27 V28	P24-C26 VanDerWaalsContact C-N 3.28Å; P24-C26 PolarHBondContact O-N 3.35Å; P24-K27 VanDerWaalsContact O-N 3.07Å; P24-K27 PolarHBondContact O-N 3.4Å; P24-K27 WeakPolarHBondContact O-CB 3.25Å; P24-V28 PolarHBondContact O-N 2.93Å; P24-V28 VanDerWaalsContact O-N 3.15Å
25	I	63.1	Low	65.2	Low	127 Å²	127	107.8 Å²	107.8	65%	0.651	61%	0.605	S	S	*	*	H	α-helix	trans	-51.3	-39.7	171.4	-59.9	165.5	0	0	0	112.7	P23 K27 V28 A29	P23-I25 PolarHBondContact O-N 3.35Å; I25-K27 VanDerWaalsContact C-N 3.34Å; I25-K27 PolarHBondContact O-N 3.36Å; I25-V28 PolarHBondContact O-N 2.99Å; I25-A29 PolarHBondContact O-N 3.48Å
26	C	64.3	Low	66.7	Low	57 Å²	57	108.4 Å²	108.4	39%	0.385	61%	0.609	S	S	.	*	H	α-helix	trans	-70.7	-29	177.7	-83.8	0	0	0	0	113.6	H22 P23 P24 S30	H22-C26 HydrophobicContact CB-CB 3.65Å; H22-C26 WeakPolarHBondContact CB-SG 3.23Å; H22-C26 PolarHBondContact ND1-SG 3.49Å; P23-C26 PolarHBondContact O-N 2.96Å; P24-C26 VanDerWaalsContact C-N 3.28Å; P24-C26 PolarHBondContact O-N 3.35Å; C26-S30 VanDerWaalsContact O-CB 3.31Å; C26-S30 WeakPolarHBondContact O-CB 3.45Å; C26-S30 PolarHBondContact O-N 3.01Å
27	K	68.7	Low	68.1	Low	162 Å²	162	112.9 Å²	112.9	70%	0.704	62%	0.617	S	S	*	*	H	α-helix	trans	-67.5	-42.3	171.6	-70.8	-176	175.8	176	0	110.6	P24 I25 S30 L31	P24-K27 VanDerWaalsContact O-N 3.07Å; P24-K27 PolarHBondContact O-N 3.4Å; P24-K27 WeakPolarHBondContact O-CB 3.25Å; I25-K27 VanDerWaalsContact C-N 3.34Å; I25-K27 PolarHBondContact O-N 3.36Å; K27-S30 PolarHBondContact O-N 3.04Å; K27-L31 WeakPolarHBondContact O-CB 3.42Å; K27-L31 VanDerWaalsContact O-CG 3.32Å; K27-L31 WeakPolarHBondContact O-CG 3.43Å; K27-L31 PolarHBondContact O-N 2.98Å
28	V	77.9	Confident	68.9	Low	89 Å²	89	113.6 Å²	113.6	54%	0.539	62%	0.618	S	S	.	*	H	α-helix	trans	-61.8	-48.2	176.1	179.2	0	0	0	0	110.6	P24 I25 S30 L31 V32	P24-V28 PolarHBondContact O-N 2.93Å; P24-V28 VanDerWaalsContact O-N 3.15Å; I25-V28 PolarHBondContact O-N 2.99Å; V28-S30 VanDerWaalsContact C-N 3.35Å; V28-S30 PolarHBondContact O-N 3Å; V28-L31 PolarHBondContact O-N 3.41Å; V28-V32 HydrophobicContact CG1-CG2 4.48Å; V28-V32 WeakPolarHBondContact O-CG2 3.47Å; V28-V32 PolarHBondContact O-N 2.91Å
29	A	75.2	Confident	69.4	Low	59 Å²	59	109.8 Å²	109.8	49%	0.488	60%	0.603	S	S	.	*	H	α-helix	trans	-61.2	-41.2	178.7	0	0	0	0	0	112.7	I25 C33	I25-A29 PolarHBondContact O-N 3.48Å; A29-C33 WeakPolarHBondContact O-CB 3.46Å; A29-C33 PolarHBondContact O-N 3.31Å
30	S	75.6	Confident	69.8	Low	61 Å²	61	111.3 Å²	111.3	43%	0.427	61%	0.611	S	S	.	*	H	α-helix	trans	-65.2	-42.5	176.5	-177.6	0	0	0	0	112.3	C26 K27 V28 C33 H34	C26-S30 VanDerWaalsContact O-CB 3.31Å; C26-S30 WeakPolarHBondContact O-CB 3.45Å; C26-S30 PolarHBondContact O-N 3.01Å; K27-S30 PolarHBondContact O-N 3.04Å; V28-S30 VanDerWaalsContact C-N 3.35Å; V28-S30 PolarHBondContact O-N 3Å; S30-C33 PolarHBondContact O-N 3.28Å; S30-H34 WeakPolarHBondContact O-CB 3.31Å; S30-H34 PolarHBondContact O-CD2 2.99Å; S30-H34 PolarHBondContact O-N 3.07Å
31	L	81.5	Confident	69.7	Low	123 Å²	123	119.2 Å²	119.2	64%	0.644	65%	0.645	S	S	*	*	H	α-helix	trans	-62.5	-45.5	176.8	-76.8	166.3	0	0	0	112.3	K27 V28 C33 H34 F35	K27-L31 WeakPolarHBondContact O-CB 3.42Å; K27-L31 VanDerWaalsContact O-CG 3.32Å; K27-L31 WeakPolarHBondContact O-CG 3.43Å; K27-L31 PolarHBondContact O-N 2.98Å; V28-L31 PolarHBondContact O-N 3.41Å; L31-C33 VanDerWaalsContact C-N 3.33Å; L31-C33 PolarHBondContact O-N 3.42Å; L31-H34 PolarHBondContact O-N 3.46Å; L31-F35 WeakPolarHBondContact O-CB 3.33Å; L31-F35 PolarHBondContact O-N 2.67Å
32	V	82.3	Confident	70.3	Confident	96 Å²	96	118.8 Å²	118.8	58%	0.582	64%	0.636	S	S	*	*	H	α-helix	trans	-62.2	-43.5	177.5	173.4	0	0	0	0	110.7	V28 F35 Y36	V28-V32 HydrophobicContact CG1-CG2 4.48Å; V28-V32 WeakPolarHBondContact O-CG2 3.47Å; V28-V32 PolarHBondContact O-N 2.91Å; V32-F35 PolarHBondContact O-N 2.72Å; V32-Y36 WeakPolarHBondContact O-CB 3.32Å; V32-Y36 PolarHBondContact O-N 3.27Å
33	C	80.8	Confident	71.1	Confident	88 Å²	88	118.1 Å²	118.1	60%	0.595	64%	0.637	S	S	*	*	H	α-helix	trans	-64.7	-42.8	179.3	-154.1	0	0	0	0	111.8	A29 S30 L31 Y36 W37	A29-C33 WeakPolarHBondContact O-CB 3.46Å; A29-C33 PolarHBondContact O-N 3.31Å; S30-C33 PolarHBondContact O-N 3.28Å; L31-C33 VanDerWaalsContact C-N 3.33Å; L31-C33 PolarHBondContact O-N 3.42Å; C33-Y36 PolarHBondContact O-N 3.15Å; C33-W37 VanDerWaalsContact O-CB 3.25Å; C33-W37 WeakPolarHBondContact O-CB 3.36Å; C33-W37 PolarHBondContact O-N 3.19Å
34	H	75.6	Confident	71.8	Confident	121 Å²	121	120.3 Å²	120.3	56%	0.56	64%	0.644	S	S	*	*	H	α-helix	trans	-62	-43.1	174.3	-94.3	-80.4	0	0	0	112.8	S30 L31 S38	S30-H34 WeakPolarHBondContact O-CB 3.31Å; S30-H34 PolarHBondContact O-CD2 2.99Å; S30-H34 PolarHBondContact O-N 3.07Å; L31-H34 PolarHBondContact O-N 3.46Å; H34-S38 VanDerWaalsContact O-CB 3.23Å; H34-S38 WeakPolarHBondContact O-CB 3.28Å; H34-S38 PolarHBondContact O-N 3.1Å; H34-S38 PolarHBondContact O-OG 3.13Å
35	F	79.2	Confident	72.5	Confident	169 Å²	169	121.5 Å²	121.5	74%	0.741	64%	0.644	S	S	*	*	H	α-helix	trans	-66.3	-41.6	-179.9	-170.1	-95.5	0	0	0	111.8	L31 V32 S39	L31-F35 WeakPolarHBondContact O-CB 3.33Å; L31-F35 PolarHBondContact O-N 2.67Å; V32-F35 PolarHBondContact O-N 2.72Å; F35-S39 PolarHBondContact O-N 3.4Å
36	Y	80.8	Confident	73.1	Confident	196 Å²	196	121.1 Å²	121.1	77%	0.769	64%	0.643	S	S	*	*	H	α-helix	trans	-68.3	-43.7	177.6	-168.9	-101.7	0	0	0	112.1	V32 C33 S39	V32-Y36 WeakPolarHBondContact O-CB 3.32Å; V32-Y36 PolarHBondContact O-N 3.27Å; C33-Y36 PolarHBondContact O-N 3.15Å; Y36-S39 PolarHBondContact O-N 2.99Å
37	W	80.7	Confident	73.6	Confident	227 Å²	227	125.4 Å²	125.4	86%	0.86	66%	0.66	S	S	*	*	H	α-helix	trans	-66.9	-35.9	178.1	-175.6	-87.1	0	0	0	113.2	C33 S39	C33-W37 VanDerWaalsContact O-CB 3.25Å; C33-W37 WeakPolarHBondContact O-CB 3.36Å; C33-W37 PolarHBondContact O-N 3.19Å; W37-S39 VanDerWaalsContact C-N 3.25Å; W37-S39 PolarHBondContact O-N 2.92Å
38	S	68.9	Low	74	Confident	83 Å²	83	122.8 Å²	122.8	58%	0.58	66%	0.657	S	S	*	*	T	Hydrogen-bonded Turn	trans	-84.3	1.5	-178.2	-49.8	0	0	0	0	113.4	H34 P40	H34-S38 VanDerWaalsContact O-CB 3.23Å; H34-S38 WeakPolarHBondContact O-CB 3.28Å; H34-S38 PolarHBondContact O-N 3.1Å; H34-S38 PolarHBondContact O-OG 3.13Å; S38-P40 WeakPolarHBondContact O-CD 3.38Å
39	S	59.8	Low	73.7	Confident	62 Å²	62	125.4 Å²	125.4	43%	0.434	67%	0.666	S	S	.	*			trans	-96.4	99.4	174.1	-163.2	0	0	0	0	108.7	F35 Y36 W37 N41	F35-S39 PolarHBondContact O-N 3.4Å; Y36-S39 PolarHBondContact O-N 2.99Å; W37-S39 VanDerWaalsContact C-N 3.25Å; W37-S39 PolarHBondContact O-N 2.92Å; S39-N41 PolarHBondContact O-N 3.22Å
40	P	62.1	Low	73.6	Confident	120 Å²	120	130.9 Å²	130.9	78%	0.779	68%	0.681	S	S	*	*			trans	-74.7	96	170.7	32.2	-31.4	0	0	0	107.2	S38	S38-P40 WeakPolarHBondContact O-CD 3.38Å
41	N	55.6	Low	73.4	Confident	225 Å²	225	137.3 Å²	137.3	100%	1.203	70%	0.704	S	S	*	*			trans	-70.6	0	147.5	-98.6	-91.8	0	0	0	108.5	S39	S39-N41 PolarHBondContact O-N 3.22Å

Retrieved 41 of 41 residues in 10.5 ms (Link to these results)

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