A0A096LQ71_POEFO Loading...

Syntaxin binding protein 1a

AlphaFold DB , UniProt , Accession A0A096LQ71, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 496 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M77.3Confident82.1Confident224 Ų22480.1 Ų80.1100%1.10344%0.436SS*.  0125.70-165.4174.7-108.600107V28M1-V28 WeakPolarHBondContact O-CB 3.48Å
2S87Confident82.1Confident80 Ų8075.1 Ų75.156%0.55941%0.411SS*.  trans-99.9145.8177.248.30000110.2V28S2-V28 WeakPolarHBondContact CA-O 3.47Å
3L91.3Very high82.3Confident63 Ų6374.8 Ų74.833%0.3342%0.415SS..EExtended strand (participates in β ladder)trans-115.4136.4-178.1-179.367.3000110.5V5 T25 V28 T29 K30L3-V5 HydrophobicContact CD1-CG2 4.37Å; L3-V5 HydrophobicContact CD2-CG2 3.58Å; L3-V5 HydrophobicContact CG-CG2 3.68Å; L3-T25 HydrophobicContact CD2-CG2 3.22Å; L3-V28 HydrophobicContact CB-CG2 4.35Å; L3-V28 PolarHBondContact N-O 3.36Å; L3-T29 CarbonylContact O-C 3.58Å; L3-T29 WeakPolarHBondContact O-CA 3.48Å; L3-K30 PolarHBondContact O-N 2.98Å
4N92.4Very high82.8Confident83 Ų8378.1 Ų78.144%0.44443%0.432SS..EExtended strand (participates in β ladder)trans-119.4121167.4-61.8-64.3000107.5F6 T31N4-F6 HydrophobicContact CB-CE2 3.77Å; N4-F6 HydrophobicContact CB-CZ 4.5Å; N4-T31 VanDerWaalsContact OD1-CB 3.29Å; N4-T31 WeakPolarHBondContact OD1-CB 3.46Å; N4-T31 PolarHBondContact OD1-N 3.33Å; N4-T31 PolarHBondContact OD1-OG1 3.4Å
5V90Very high83.4Confident28 Ų2879.4 Ų79.417%0.1745%0.445CS..EExtended strand (participates in β ladder)trans-108.7124.9-176.7-174.80000108.6L3 F7 T29 T31 L32 T33L3-V5 HydrophobicContact CD1-CG2 4.37Å; L3-V5 HydrophobicContact CD2-CG2 3.58Å; L3-V5 HydrophobicContact CG-CG2 3.68Å; V5-F7 HydrophobicContact CG1-CD1 4.37Å; V5-F7 HydrophobicContact CG1-CD2 4.36Å; V5-F7 HydrophobicContact CG1-CE1 3.97Å; V5-F7 HydrophobicContact CG1-CE2 3.97Å; V5-F7 HydrophobicContact CG1-CZ 3.76Å; V5-T29 HydrophobicContact CG2-CG2 4.25Å; V5-T31 PolarHBondContact N-O 2.87Å; V5-L32 WeakPolarHBondContact O-CA 3.45Å; V5-T33 PolarHBondContact O-N 3.25Å; V5-T33 VanDerWaalsContact O-N 3.1Å
6F90.8Very high83.9Confident112 Ų11280.8 Ų80.849%0.49145%0.45SS..EExtended strand (participates in β ladder)trans-122.3109.6174.4-62.8-91.9000107.5N4 T31 T33 I35N4-F6 HydrophobicContact CB-CE2 3.77Å; N4-F6 HydrophobicContact CB-CZ 4.5Å; F6-T31 HydrophobicContact CE1-CG2 4.28Å; F6-T31 HydrophobicContact CZ-CG2 4.13Å; F6-T33 CarbonylContact C-O 3.56Å; F6-T33 WeakPolarHBondContact CA-O 3.39Å; F6-T33 HydrophobicContact CD1-CG2 3.25Å; F6-T33 HydrophobicContact CE1-CG2 3.47Å; F6-T33 VanDerWaalsContact CE1-CG2 3.47Å; F6-T33 HydrophobicContact CG-CG2 4.23Å; F6-I35 HydrophobicContact CB-CG2 4.29Å; F6-I35 HydrophobicContact CD1-CG2 4.15Å
7F88.8Confident84.3Confident50 Ų5080.2 Ų80.222%0.21944%0.442CS..EExtended strand (participates in β ladder)trans-79.5123.2176.6-66.8-67000110.1V5 C12 L20 L32 T33 E34 I35V5-F7 HydrophobicContact CG1-CD1 4.37Å; V5-F7 HydrophobicContact CG1-CD2 4.36Å; V5-F7 HydrophobicContact CG1-CE1 3.97Å; V5-F7 HydrophobicContact CG1-CE2 3.97Å; V5-F7 HydrophobicContact CG1-CZ 3.76Å; F7-C12 HydrophobicContact CD2-CB 4.11Å; F7-C12 HydrophobicContact CE2-CB 3.98Å; F7-C12 HydrophobicContact CG-CB 4.46Å; F7-C12 HydrophobicContact CZ-CB 4.22Å; F7-L20 HydrophobicContact CE2-CD2 4.45Å; F7-L20 HydrophobicContact CZ-CD2 3.84Å; F7-L32 HydrophobicContact CE2-CD1 4.19Å; F7-L32 HydrophobicContact CE2-CD2 4.11Å; F7-L32 HydrophobicContact CE2-CG 4Å; F7-T33 PolarHBondContact N-O 2.86Å; F7-E34 HydrophobicContact CB-CG 4.22Å; F7-E34 HydrophobicContact CD2-CG 4.32Å; F7-I35 VanDerWaalsContact O-CG1 3.3Å; F7-I35 WeakPolarHBondContact O-CG1 3.46Å; F7-I35 PolarHBondContact O-N 2.71Å
8V79.5Confident84.8Confident82 Ų8280.1 Ų80.150%0.49744%0.44SS..SBendtrans-82.8-43.5-178-177.60000110.9I35 I37V8-I35 HydrophobicContact CB-CD1 4.36Å; V8-I35 HydrophobicContact CG1-CD1 4.34Å; V8-I35 HydrophobicContact CG2-CD1 4.05Å; V8-I37 WeakPolarHBondContact CG1-O 3.46Å; V8-I37 CarbonylContact O-C 3.56Å; V8-I37 PolarHBondContact O-N 2.79Å
9F70.3Confident85.3Confident81 Ų8182.9 Ų82.936%0.35545%0.45SS..SBendtrans-75.5144.3173.9-153.6-97.7000109.7A38 R73 E76 Q77F9-A38 HydrophobicContact CD2-CB 4.09Å; F9-R73 HydrophobicContact CE2-CG 4.05Å; F9-R73 HydrophobicContact CZ-CB 4.3Å; F9-R73 HydrophobicContact CZ-CG 3.76Å; F9-E76 WeakPolarHBondContact CE1-OE2 3.38Å; F9-Q77 HydrophobicContact CE2-CG 3.84Å; F9-Q77 HydrophobicContact CZ-CG 4.48Å
10P65.8Low85.6Confident12 Ų1280.8 Ų80.88%0.07844%0.438CS..SBendtrans-60.3164.2-176.820.5-29.6000112.9E76 T80P10-E76 HydrophobicContact CG-CB 3.75Å; P10-E76 HydrophobicContact CG-CG 4.28Å; P10-T80 HydrophobicContact CB-CG2 4.35Å; P10-T80 HydrophobicContact CG-CG2 4.11Å
11A69.9Low85.9Confident66 Ų6680 Ų8055%0.54544%0.436SS..SBendtrans10.9101.8-179.900000114.9P13 E34A11-P13 VanDerWaalsContact O-CD 3.29Å; A11-P13 WeakPolarHBondContact O-CD 3.42Å; A11-E34 WeakPolarHBondContact CA-OE1 3.42Å
12C81.8Confident86.7Confident20 Ų2077.6 Ų77.614%0.13542%0.419CS..  trans-52.5119.3174.7-175.60000109F7 D14 F17 E34F7-C12 HydrophobicContact CD2-CB 4.11Å; F7-C12 HydrophobicContact CE2-CB 3.98Å; F7-C12 HydrophobicContact CG-CB 4.46Å; F7-C12 HydrophobicContact CZ-CB 4.22Å; C12-D14 PolarHBondContact O-N 3.11Å; C12-F17 HydrophobicContact CB-CB 4.5Å; C12-E34 PolarHBondContact N-OE1 3.46Å
13P85.4Confident87.1Confident72 Ų7275.5 Ų75.547%0.46841%0.405SS..  trans-55.7134.7-174.7-27.934.1000111.2A11 L16 F17A11-P13 VanDerWaalsContact O-CD 3.29Å; A11-P13 WeakPolarHBondContact O-CD 3.42Å; P13-L16 HydrophobicContact CB-CD1 4.5Å; P13-L16 HydrophobicContact CG-CD1 4.21Å; P13-L16 WeakPolarHBondContact O-CA 3.49Å; P13-L16 PolarHBondContact O-N 3.16Å; P13-F17 PolarHBondContact O-N 3.2Å
14D88.7Confident87.2Confident121 Ų12183.4 Ų83.465%0.64743%0.43SS*.Hα-helixtrans-45.9-41-177.9-76.2-13.3000113.9C12 L16 N18C12-D14 PolarHBondContact O-N 3.11Å; D14-L16 PolarHBondContact O-N 2.83Å; D14-N18 WeakPolarHBondContact O-CB 3.49Å; D14-N18 PolarHBondContact O-N 3.19Å; D14-N18 PolarHBondContact O-ND2 3.29Å
15P92.3Very high87.1Confident97 Ų9782.1 Ų82.163%0.6343%0.426SS*.Hα-helixtrans-60.7-44.3176.1-24.435.8000113.5N18 E19P15-N18 PolarHBondContact O-N 3.01Å; P15-E19 PolarHBondContact O-N 3.48Å
16L91.1Very high87.2Confident101 Ų10183 Ų8353%0.52943%0.433SS..Hα-helixtrans-72.2-39.5179.7-67.6177.2000111.4P13 D14 N18 E19 L20P13-L16 HydrophobicContact CB-CD1 4.5Å; P13-L16 HydrophobicContact CG-CD1 4.21Å; P13-L16 WeakPolarHBondContact O-CA 3.49Å; P13-L16 PolarHBondContact O-N 3.16Å; D14-L16 PolarHBondContact O-N 2.83Å; L16-N18 VanDerWaalsContact C-N 3.34Å; L16-N18 PolarHBondContact O-N 3.03Å; L16-E19 PolarHBondContact O-N 2.77Å; L16-L20 WeakPolarHBondContact O-CB 3.13Å; L16-L20 PolarHBondContact O-N 2.82Å
17F91.3Very high87.3Confident72 Ų7286.6 Ų86.632%0.31645%0.448SS..Hα-helixtrans-61-45.1173.7-176.9-104000111.1C12 P13 E19 L20 V21 L32C12-F17 HydrophobicContact CB-CB 4.5Å; P13-F17 PolarHBondContact O-N 3.2Å; F17-E19 VanDerWaalsContact C-N 3.28Å; F17-E19 PolarHBondContact O-N 3.33Å; F17-L20 WeakPolarHBondContact O-CB 3.49Å; F17-L20 PolarHBondContact O-N 3.07Å; F17-L20 VanDerWaalsContact O-N 3.15Å; F17-V21 HydrophobicContact CD1-CG1 4.26Å; F17-V21 HydrophobicContact CE1-CG1 3.79Å; F17-V21 HydrophobicContact CE2-CG1 4.16Å; F17-V21 HydrophobicContact CZ-CG1 3.74Å; F17-V21 WeakPolarHBondContact O-CG1 3.31Å; F17-V21 PolarHBondContact O-N 3.44Å; F17-L32 HydrophobicContact CD2-CD2 4.39Å; F17-L32 HydrophobicContact CE2-CD1 4.17Å; F17-L32 HydrophobicContact CE2-CD2 3.63Å
18N92.6Very high87.6Confident77 Ų7787.1 Ų87.141%0.41246%0.456SS..Hα-helixtrans-63.1-32.1176.8-79.1-47.2000113.2D14 P15 L16 V21 K22D14-N18 WeakPolarHBondContact O-CB 3.49Å; D14-N18 PolarHBondContact O-N 3.19Å; D14-N18 PolarHBondContact O-ND2 3.29Å; P15-N18 PolarHBondContact O-N 3.01Å; L16-N18 VanDerWaalsContact C-N 3.34Å; L16-N18 PolarHBondContact O-N 3.03Å; N18-V21 VanDerWaalsContact O-CG2 3.25Å; N18-V21 WeakPolarHBondContact O-CG2 3.27Å; N18-K22 WeakPolarHBondContact O-CD 3.4Å; N18-K22 VanDerWaalsContact O-CG 3.25Å; N18-K22 WeakPolarHBondContact O-CG 3.16Å; N18-K22 PolarHBondContact O-N 3.4Å
19E94.2Very high88.2Confident135 Ų13584.7 Ų84.763%0.63144%0.441SS*.Hα-helixtrans-70.3-44.9172.1-171.1176.717000111.3P15 L16 F17 V21 K22 S23P15-E19 PolarHBondContact O-N 3.48Å; L16-E19 PolarHBondContact O-N 2.77Å; F17-E19 VanDerWaalsContact C-N 3.28Å; F17-E19 PolarHBondContact O-N 3.33Å; E19-V21 PolarHBondContact O-N 2.7Å; E19-K22 PolarHBondContact O-N 3.34Å; E19-K22 VanDerWaalsContact O-N 3.16Å; E19-S23 PolarHBondContact O-N 3.47Å
20L91.1Very high89.4Confident40 Ų4088.7 Ų88.721%0.20946%0.458CS..Hα-helixtrans-59.8-44.4178.9-179.862.3000112.1F7 L16 F17 K22 S23 L32F7-L20 HydrophobicContact CE2-CD2 4.45Å; F7-L20 HydrophobicContact CZ-CD2 3.84Å; L16-L20 WeakPolarHBondContact O-CB 3.13Å; L16-L20 PolarHBondContact O-N 2.82Å; F17-L20 WeakPolarHBondContact O-CB 3.49Å; F17-L20 PolarHBondContact O-N 3.07Å; F17-L20 VanDerWaalsContact O-N 3.15Å; L20-K22 VanDerWaalsContact C-N 3.27Å; L20-K22 PolarHBondContact O-N 2.8Å; L20-S23 WeakPolarHBondContact O-CB 3.49Å; L20-S23 PolarHBondContact O-N 2.9Å; L20-S23 VanDerWaalsContact O-N 3.16Å; L20-S23 PolarHBondContact O-OG 2.84Å; L20-L32 HydrophobicContact CD2-CD1 3.59Å
21V92.4Very high90.7Very high63 Ų6390.7 Ų90.738%0.38247%0.47SS..Hα-helixtrans-66.3-29.1178.9-60.40000112.6F17 N18 E19 S26F17-V21 HydrophobicContact CD1-CG1 4.26Å; F17-V21 HydrophobicContact CE1-CG1 3.79Å; F17-V21 HydrophobicContact CE2-CG1 4.16Å; F17-V21 HydrophobicContact CZ-CG1 3.74Å; F17-V21 WeakPolarHBondContact O-CG1 3.31Å; F17-V21 PolarHBondContact O-N 3.44Å; N18-V21 VanDerWaalsContact O-CG2 3.25Å; N18-V21 WeakPolarHBondContact O-CG2 3.27Å; E19-V21 PolarHBondContact O-N 2.7Å; V21-S26 VanDerWaalsContact O-CB 3.31Å; V21-S26 WeakPolarHBondContact O-CB 3.5Å; V21-S26 PolarHBondContact O-OG 3.35Å; V21-S26 VanDerWaalsContact O-OG 3.07Å
22K94.5Very high91.7Very high174 Ų17490.8 Ų90.876%0.75746%0.461SS*.Hα-helixtrans-80.8-18.1175.5-69.8171.9-171.4171.40113.2N18 E19 L20N18-K22 WeakPolarHBondContact O-CD 3.4Å; N18-K22 VanDerWaalsContact O-CG 3.25Å; N18-K22 WeakPolarHBondContact O-CG 3.16Å; N18-K22 PolarHBondContact O-N 3.4Å; E19-K22 PolarHBondContact O-N 3.34Å; E19-K22 VanDerWaalsContact O-N 3.16Å; L20-K22 VanDerWaalsContact C-N 3.27Å; L20-K22 PolarHBondContact O-N 2.8Å
23S94.3Very high92.1Very high36 Ų3692.8 Ų92.825%0.25247%0.473SS..SBendtrans-68.3164.4-179.980.70000112.6E19 L20 T25 S26E19-S23 PolarHBondContact O-N 3.47Å; L20-S23 WeakPolarHBondContact O-CB 3.49Å; L20-S23 PolarHBondContact O-N 2.9Å; L20-S23 VanDerWaalsContact O-N 3.16Å; L20-S23 PolarHBondContact O-OG 2.84Å; S23-T25 PolarHBondContact O-N 3.43Å; S23-T25 VanDerWaalsContact OG-CB 3.29Å; S23-T25 WeakPolarHBondContact OG-CB 3.42Å; S23-T25 PolarHBondContact OG-N 3.24Å; S23-T25 PolarHBondContact OG-OG1 3.2Å; S23-S26 PolarHBondContact O-N 3.34Å; S23-S26 PolarHBondContact O-OG 3.17Å
24R93.5Very high92.3Very high229 Ų22992.9 Ų92.986%0.86447%0.467SS*.G310 helixtrans-64.7-21.6171.6-64.9-177.8-176.2-178.31.9112.4S26 K27R24-S26 VanDerWaalsContact C-N 3.29Å; R24-S26 PolarHBondContact O-N 3.19Å; R24-K27 PolarHBondContact O-N 2.79Å
25T91.3Very high92.2Very high57 Ų5790.8 Ų90.835%0.3546%0.455SS..G310 helixtrans-69.3-26.9-176.3-45.50000112.1L3 S23 K27 V28 T29L3-T25 HydrophobicContact CD2-CG2 3.22Å; S23-T25 PolarHBondContact O-N 3.43Å; S23-T25 VanDerWaalsContact OG-CB 3.29Å; S23-T25 WeakPolarHBondContact OG-CB 3.42Å; S23-T25 PolarHBondContact OG-N 3.24Å; S23-T25 PolarHBondContact OG-OG1 3.2Å; T25-K27 VanDerWaalsContact C-N 3.25Å; T25-K27 PolarHBondContact O-N 3.1Å; T25-V28 HydrophobicContact CG2-CG2 4.37Å; T25-V28 WeakPolarHBondContact O-CG2 3.38Å; T25-V28 PolarHBondContact O-N 3.33Å; T25-V28 VanDerWaalsContact O-N 3.14Å; T25-T29 PolarHBondContact O-N 3.49Å; T25-T29 VanDerWaalsContact O-N 3.14Å; T25-T29 PolarHBondContact O-OG1 2.62Å
26S91.9Very high92Very high46 Ų4688.1 Ų88.132%0.32244%0.436SS..G310 helixtrans-57.8-37.6176.3650000112.4V21 S23 R24 V28 T29V21-S26 VanDerWaalsContact O-CB 3.31Å; V21-S26 WeakPolarHBondContact O-CB 3.5Å; V21-S26 PolarHBondContact O-OG 3.35Å; V21-S26 VanDerWaalsContact O-OG 3.07Å; S23-S26 PolarHBondContact O-N 3.34Å; S23-S26 PolarHBondContact O-OG 3.17Å; R24-S26 VanDerWaalsContact C-N 3.29Å; R24-S26 PolarHBondContact O-N 3.19Å; S26-V28 PolarHBondContact O-N 3.34Å; S26-T29 PolarHBondContact O-N 2.93Å
27K92.4Very high92Very high187 Ų18786.6 Ų86.681%0.81343%0.427SS*.G310 helixtrans-66-23.2-179.5-61.7-176.1-179.3-177.90114.2R24 T25R24-K27 PolarHBondContact O-N 2.79Å; T25-K27 VanDerWaalsContact C-N 3.25Å; T25-K27 PolarHBondContact O-N 3.1Å
28V95.1Very high92.2Very high62 Ų6283.6 Ų83.638%0.37642%0.416SS..G310 helixtrans-106.2-5.3-179.6-63.40000112.8M1 S2 L3 T25 S26M1-V28 WeakPolarHBondContact O-CB 3.48Å; S2-V28 WeakPolarHBondContact CA-O 3.47Å; L3-V28 HydrophobicContact CB-CG2 4.35Å; L3-V28 PolarHBondContact N-O 3.36Å; T25-V28 HydrophobicContact CG2-CG2 4.37Å; T25-V28 WeakPolarHBondContact O-CG2 3.38Å; T25-V28 PolarHBondContact O-N 3.33Å; T25-V28 VanDerWaalsContact O-N 3.14Å; S26-V28 PolarHBondContact O-N 3.34Å
29T93.1Very high92.4Very high31 Ų3181.2 Ų81.219%0.1940%0.402CS..EExtended strand (participates in β ladder)trans-76.8122.4179.1-58.40000110L3 V5 T25 S26 T31 L32L3-T29 CarbonylContact O-C 3.58Å; L3-T29 WeakPolarHBondContact O-CA 3.48Å; V5-T29 HydrophobicContact CG2-CG2 4.25Å; T25-T29 PolarHBondContact O-N 3.49Å; T25-T29 VanDerWaalsContact O-N 3.14Å; T25-T29 PolarHBondContact O-OG1 2.62Å; S26-T29 PolarHBondContact O-N 2.93Å; T29-T31 WeakPolarHBondContact CG2-O 3.37Å; T29-L32 HydrophobicContact CG2-CB 4.01Å; T29-L32 HydrophobicContact CG2-CD1 4.37Å
30K95.1Very high92.5Very high164 Ų16478.7 Ų78.771%0.71339%0.392SS*.EExtended strand (participates in β ladder)trans-101.4-37.5179.3-70.5-61.9-173.6-176.80112.5L3L3-K30 PolarHBondContact O-N 2.98Å
31T92.6Very high92.8Very high55 Ų5581.5 Ų81.534%0.33741%0.413SS..EExtended strand (participates in β ladder)trans-130133.3177.3-490000107.7N4 V5 F6 T29 T33N4-T31 VanDerWaalsContact OD1-CB 3.29Å; N4-T31 WeakPolarHBondContact OD1-CB 3.46Å; N4-T31 PolarHBondContact OD1-N 3.33Å; N4-T31 PolarHBondContact OD1-OG1 3.4Å; V5-T31 PolarHBondContact N-O 2.87Å; F6-T31 HydrophobicContact CE1-CG2 4.28Å; F6-T31 HydrophobicContact CZ-CG2 4.13Å; T29-T31 WeakPolarHBondContact CG2-O 3.37Å; T31-T33 HydrophobicContact CG2-CG2 4.26Å
32L91.4Very high93Very high68 Ų6880.9 Ų80.936%0.35640%0.404SS..EExtended strand (participates in β ladder)trans-139111171.3-174.5146000106.9V5 F7 F17 L20 T29V5-L32 WeakPolarHBondContact O-CA 3.45Å; F7-L32 HydrophobicContact CE2-CD1 4.19Å; F7-L32 HydrophobicContact CE2-CD2 4.11Å; F7-L32 HydrophobicContact CE2-CG 4Å; F17-L32 HydrophobicContact CD2-CD2 4.39Å; F17-L32 HydrophobicContact CE2-CD1 4.17Å; F17-L32 HydrophobicContact CE2-CD2 3.63Å; L20-L32 HydrophobicContact CD2-CD1 3.59Å; T29-L32 HydrophobicContact CG2-CB 4.01Å; T29-L32 HydrophobicContact CG2-CD1 4.37Å
33T90.6Very high93.2Very high61 Ų6173.2 Ų73.237%0.37437%0.371SS..EExtended strand (participates in β ladder)trans-150.1165.7-175.1-166.50000110.7V5 F6 F7 T31V5-T33 PolarHBondContact O-N 3.25Å; V5-T33 VanDerWaalsContact O-N 3.1Å; F6-T33 CarbonylContact C-O 3.56Å; F6-T33 WeakPolarHBondContact CA-O 3.39Å; F6-T33 HydrophobicContact CD1-CG2 3.25Å; F6-T33 HydrophobicContact CE1-CG2 3.47Å; F6-T33 VanDerWaalsContact CE1-CG2 3.47Å; F6-T33 HydrophobicContact CG-CG2 4.23Å; F7-T33 PolarHBondContact N-O 2.86Å; T31-T33 HydrophobicContact CG2-CG2 4.26Å
34E88.3Confident93.3Very high74 Ų7475.1 Ų75.135%0.34638%0.384SS..EExtended strand (participates in β ladder)trans-116.1127.3-177.1-55.8-178.4162.300107.8F7 A11 C12F7-E34 HydrophobicContact CB-CG 4.22Å; F7-E34 HydrophobicContact CD2-CG 4.32Å; A11-E34 WeakPolarHBondContact CA-OE1 3.42Å; C12-E34 PolarHBondContact N-OE1 3.46Å
35I87.8Confident93.6Very high77 Ų7765.2 Ų65.240%0.39535%0.348SS..  trans-90.5-19.5179.460.4165.9000112.3F6 F7 V8 I37F6-I35 HydrophobicContact CB-CG2 4.29Å; F6-I35 HydrophobicContact CD1-CG2 4.15Å; F7-I35 VanDerWaalsContact O-CG1 3.3Å; F7-I35 WeakPolarHBondContact O-CG1 3.46Å; F7-I35 PolarHBondContact O-N 2.71Å; V8-I35 HydrophobicContact CB-CD1 4.36Å; V8-I35 HydrophobicContact CG1-CD1 4.34Å; V8-I35 HydrophobicContact CG2-CD1 4.05Å; I35-I37 HydrophobicContact CD1-CB 4.35Å; I35-I37 PolarHBondContact O-N 2.92Å
36N86.9Confident93.9Very high42 Ų4262.6 Ų62.623%0.22533%0.332CS..  trans53.550.4179.9-65.4-51.4000113.1T80 Y114N36-T80 HydrophobicContact CB-CG2 4.47Å; N36-T80 VanDerWaalsContact O-CB 3.28Å; N36-T80 WeakPolarHBondContact O-CB 3.3Å; N36-Y114 HydrophobicContact CB-CE1 4.38Å; N36-Y114 PolarHBondContact OD1-OH 2.87Å
37I92.2Very high94.2Very high68 Ų6860.6 Ų60.635%0.34932%0.317SS..  trans-131.992.9175.3-58.2174.6000107.2V8 I35 F39V8-I37 WeakPolarHBondContact CG1-O 3.46Å; V8-I37 CarbonylContact O-C 3.56Å; V8-I37 PolarHBondContact O-N 2.79Å; I35-I37 HydrophobicContact CD1-CB 4.35Å; I35-I37 PolarHBondContact O-N 2.92Å; I37-F39 HydrophobicContact CG2-CD1 4.22Å; I37-F39 HydrophobicContact CG2-CE1 3.86Å; I37-F39 HydrophobicContact CG2-CZ 4.32Å
38A94.4Very high94.5Very high9 Ų952.2 Ų52.27%0.07428%0.282CS..  trans-116.140.3-17400000112.3F9 Q77 T80F9-A38 HydrophobicContact CD2-CB 4.09Å; A38-Q77 HydrophobicContact CB-CB 4.38Å; A38-Q77 HydrophobicContact CB-CG 3.87Å; A38-Q77 WeakPolarHBondContact O-CB 3.18Å; A38-Q77 VanDerWaalsContact O-CG 3.27Å; A38-Q77 WeakPolarHBondContact O-CG 3.4Å; A38-Q77 PolarHBondContact O-NE2 3.45Å; A38-T80 HydrophobicContact CB-CG2 4Å; A38-T80 PolarHBondContact N-OG1 3.49Å
39F96.2Very high94.6Very high27 Ų2749.3 Ų49.312%0.11826%0.264CS..SBendtrans-143.3159176.568.1-85000110.3I37 P41 L49 L81 T84I37-F39 HydrophobicContact CG2-CD1 4.22Å; I37-F39 HydrophobicContact CG2-CE1 3.86Å; I37-F39 HydrophobicContact CG2-CZ 4.32Å; F39-P41 HydrophobicContact CE2-CB 4.38Å; F39-L49 HydrophobicContact CB-CD2 3.76Å; F39-L81 HydrophobicContact CD1-CB 3.94Å; F39-L81 HydrophobicContact CD1-CD1 4.3Å; F39-L81 HydrophobicContact CD2-CD1 4.02Å; F39-L81 HydrophobicContact CE1-CB 4.03Å; F39-L81 HydrophobicContact CE1-CD1 3.94Å; F39-L81 HydrophobicContact CE2-CD1 3.61Å; F39-L81 HydrophobicContact CG-CB 4.38Å; F39-L81 HydrophobicContact CG-CD1 4.35Å; F39-L81 HydrophobicContact CZ-CD1 3.57Å; F39-T84 HydrophobicContact CZ-CG2 4.38Å
40L96.8Very high94.8Very high82 Ų8252.8 Ų52.843%0.42928%0.282SS..EExtended strand (participates in β ladder)trans-98122173.9-57-176000109.7Y42 Y47 S48 D50L40-Y42 VanDerWaalsContact C-N 3.26Å; L40-Y42 PolarHBondContact O-N 3.34Å; L40-Y47 CarbonylContact O-C 3.5Å; L40-Y47 VanDerWaalsContact O-CA 3.28Å; L40-Y47 WeakPolarHBondContact O-CA 3.01Å; L40-S48 PolarHBondContact N-O 3.15Å; L40-S48 PolarHBondContact O-N 3.23Å; L40-D50 HydrophobicContact CD1-CB 3.71Å; L40-D50 HydrophobicContact CG-CB 4.17Å
41P97.1Very high94.8Very high99 Ų9945.6 Ų45.664%0.64325%0.251SS*.EExtended strand (participates in β ladder)trans-76.77917032.4-33.4000109.4F39 E43F39-P41 HydrophobicContact CE2-CB 4.38Å; P41-E43 VanDerWaalsContact C-N 3.35Å; P41-E43 PolarHBondContact O-N 3.3Å
42Y97.8Very high95Very high50 Ų5045.7 Ų45.720%0.19625%0.252CS..EExtended strand (participates in β ladder)trans-62.1-41.8-174.3-175.9-110.5000112.1L40 V46 D164 F449 M452 I474L40-Y42 VanDerWaalsContact C-N 3.26Å; L40-Y42 PolarHBondContact O-N 3.34Å; Y42-V46 HydrophobicContact CD1-CB 4.47Å; Y42-V46 HydrophobicContact CD1-CG1 4.1Å; Y42-V46 PolarHBondContact N-O 3.33Å; Y42-D164 WeakPolarHBondContact CE2-OD2 3.33Å; Y42-D164 PolarHBondContact OH-OD1 3.03Å; Y42-F449 HydrophobicContact CE1-CE1 4.31Å; Y42-M452 HydrophobicContact CD1-CE 3.93Å; Y42-M452 HydrophobicContact CE1-CE 3.69Å; Y42-I474 HydrophobicContact CD1-CG1 3.98Å; Y42-I474 HydrophobicContact CE1-CG1 4.09Å; Y42-I474 HydrophobicContact CG-CG1 4.4Å
43E98.4Very high95Very high13 Ų1347.6 Ų47.66%0.06126%0.263CS..EExtended strand (participates in β ladder)trans-139.6173.9169.6-56.7-169.6145.600110.1P41 Q45 V46 Q152 E185 R194 M452 Y456P41-E43 VanDerWaalsContact C-N 3.35Å; P41-E43 PolarHBondContact O-N 3.3Å; E43-Q45 PolarHBondContact O-N 2.91Å; E43-Q45 VanDerWaalsContact O-N 3.13Å; E43-V46 HydrophobicContact CB-CB 3.82Å; E43-V46 HydrophobicContact CB-CG2 3.98Å; E43-V46 HydrophobicContact CG-CB 4.15Å; E43-V46 HydrophobicContact CG-CG2 4.25Å; E43-V46 PolarHBondContact N-O 3.41Å; E43-V46 PolarHBondContact O-N 2.76Å; E43-V46 VanDerWaalsContact O-N 3.15Å; E43-V46 WeakPolarHBondContact OE2-CG2 3.25Å; E43-Q152 PolarHBondContact OE1-NE2 3.04Å; E43-E185 WeakPolarHBondContact CA-OE1 3.18Å; E43-E185 VanDerWaalsContact CB-OE1 3.27Å; E43-E185 WeakPolarHBondContact CB-OE1 3.2Å; E43-R194 VanDerWaalsContact CD-CZ 3.48Å; E43-R194 IonicContact OE1-CZ 3.64Å; E43-R194 IonicContact OE1-NE 3.54Å; E43-R194 IonicContact OE1-NH1 2.84Å; E43-R194 PolarHBondContact OE1-NH1 3.37Å; E43-R194 IonicContact OE2-CZ 3.73Å; E43-R194 IonicContact OE2-NE 3.79Å; E43-R194 IonicContact OE2-NH1 3.81Å; E43-R194 PolarHBondContact OE2-NH1 2.97Å; E43-R194 IonicContact OE2-NH2 2.76Å; E43-M452 HydrophobicContact CG-CE 4.25Å; E43-Y456 WeakPolarHBondContact CB-OH 3.23Å; E43-Y456 WeakPolarHBondContact OE2-CE2 3.24Å; E43-Y456 PolarHBondContact OE2-OH 3.04Å
44S97Very high95.2Very high77 Ų7744.7 Ų44.754%0.53825%0.245SC..THydrogen-bonded Turntrans-54.9-31.1178.545.40000114.7E185 Y456S44-E185 PolarHBondContact N-OE1 3.17Å; S44-E185 PolarHBondContact OG-OE1 3.46Å; S44-Y456 PolarHBondContact OG-OH 3.23Å
45Q98.1Very high95.6Very high20 Ų2041.2 Ų41.29%0.09323%0.229CC..THydrogen-bonded Turntrans-121.614.3174.9-65.4177.9-123.500113.3E43 A455 Y456 T459 A467 I468 I469E43-Q45 PolarHBondContact O-N 2.91Å; E43-Q45 VanDerWaalsContact O-N 3.13Å; Q45-A455 PolarHBondContact NE2-O 3.26Å; Q45-A455 VanDerWaalsContact NE2-O 3.17Å; Q45-Y456 HydrophobicContact CB-CD1 4.31Å; Q45-Y456 HydrophobicContact CB-CE1 3.72Å; Q45-Y456 HydrophobicContact CB-CE2 4.24Å; Q45-Y456 HydrophobicContact CG-CD1 4.19Å; Q45-Y456 HydrophobicContact CG-CE1 3.79Å; Q45-Y456 PolarHBondContact N-OH 3.18Å; Q45-T459 PolarHBondContact NE2-OG1 3.24Å; Q45-A467 PolarHBondContact NE2-O 3.24Å; Q45-I468 WeakPolarHBondContact O-CA 3.41Å; Q45-I469 PolarHBondContact O-N 3.01Å
46V98.8Very high95.9Very high3 Ų338.8 Ų38.82%0.01822%0.216CC..EExtended strand (participates in β ladder)trans-127.5129.9-177.8-172.80000111.4Y42 E43 M452 Y456 I469 I474Y42-V46 HydrophobicContact CD1-CB 4.47Å; Y42-V46 HydrophobicContact CD1-CG1 4.1Å; Y42-V46 PolarHBondContact N-O 3.33Å; E43-V46 HydrophobicContact CB-CB 3.82Å; E43-V46 HydrophobicContact CB-CG2 3.98Å; E43-V46 HydrophobicContact CG-CB 4.15Å; E43-V46 HydrophobicContact CG-CG2 4.25Å; E43-V46 PolarHBondContact N-O 3.41Å; E43-V46 PolarHBondContact O-N 2.76Å; E43-V46 VanDerWaalsContact O-N 3.15Å; E43-V46 WeakPolarHBondContact OE2-CG2 3.25Å; V46-M452 HydrophobicContact CB-CE 4.35Å; V46-M452 HydrophobicContact CG1-CE 4.05Å; V46-M452 HydrophobicContact CG1-CG 3.9Å; V46-M452 HydrophobicContact CG1-SD 4.17Å; V46-M452 HydrophobicContact CG2-CB 3.97Å; V46-M452 HydrophobicContact CG2-CE 3.93Å; V46-M452 HydrophobicContact CG2-CG 3.9Å; V46-Y456 HydrophobicContact CG2-CE2 4Å; V46-I469 CarbonylContact C-O 3.6Å; V46-I469 WeakPolarHBondContact CA-O 3.5Å; V46-I469 HydrophobicContact CG2-CG2 3.96Å; V46-I474 HydrophobicContact CG1-CD1 3.95Å
47Y98.6Very high96.2Very high4 Ų437.1 Ų37.12%0.01621%0.208CC..EExtended strand (participates in β ladder)trans-122.4148.9173.969.1-84.7000112.7L40 L49 L78 L81 V441 F442 I468 I469 G470 S471L40-Y47 CarbonylContact O-C 3.5Å; L40-Y47 VanDerWaalsContact O-CA 3.28Å; L40-Y47 WeakPolarHBondContact O-CA 3.01Å; Y47-L49 HydrophobicContact CD2-CD2 4.05Å; Y47-L49 HydrophobicContact CE2-CD2 4.21Å; Y47-L78 HydrophobicContact CE2-CD2 3.7Å; Y47-L78 WeakPolarHBondContact OH-CD2 3.15Å; Y47-L81 HydrophobicContact CD1-CD2 3.65Å; Y47-L81 HydrophobicContact CD2-CD2 3.93Å; Y47-L81 HydrophobicContact CE1-CD2 3.46Å; Y47-L81 VanDerWaalsContact CE1-CD2 3.46Å; Y47-L81 HydrophobicContact CE2-CD2 3.76Å; Y47-L81 HydrophobicContact CG-CD2 3.87Å; Y47-V441 PolarHBondContact OH-O 3.26Å; Y47-F442 AromaticContact CE2-CD2 3.93Å; Y47-F442 HydrophobicContact CE2-CD2 3.93Å; Y47-F442 HydrophobicContact CE2-CE2 4.46Å; Y47-F442 WeakPolarHBondContact OH-CB 3.38Å; Y47-I468 HydrophobicContact CD1-CG2 3.67Å; Y47-I468 HydrophobicContact CE1-CG2 3.96Å; Y47-I469 WeakPolarHBondContact CD1-O 3.25Å; Y47-I469 PolarHBondContact N-O 3.35Å; Y47-G470 VanDerWaalsContact CE1-CA 3.47Å; Y47-G470 VanDerWaalsContact CE1-N 3.3Å; Y47-G470 WeakPolarHBondContact O-CA 3.49Å; Y47-S471 PolarHBondContact O-N 3.01Å
48S98.5Very high96.3Very high10 Ų1034.1 Ų34.17%0.0719%0.192CC..EExtended strand (participates in β ladder)trans-121.8143.7173.5177.70000110L40 D50L40-S48 PolarHBondContact N-O 3.15Å; L40-S48 PolarHBondContact O-N 3.23Å; S48-D50 VanDerWaalsContact C-N 3.33Å; S48-D50 PolarHBondContact OG-N 3.46Å; S48-D50 VanDerWaalsContact OG-N 3.16Å
49L97.9Very high96.4Very high1 Ų134 Ų341%0.00519%0.19CC..  trans-92.43.2172.4-56.2-170.8000113.4F39 Y47 N51 L74 Q77 L78 F442 S471F39-L49 HydrophobicContact CB-CD2 3.76Å; Y47-L49 HydrophobicContact CD2-CD2 4.05Å; Y47-L49 HydrophobicContact CE2-CD2 4.21Å; L49-N51 PolarHBondContact O-N 2.91Å; L49-L74 HydrophobicContact CB-CD2 4.35Å; L49-L74 HydrophobicContact CD1-CB 4.38Å; L49-L74 HydrophobicContact CD1-CD2 3.76Å; L49-Q77 HydrophobicContact CD1-CB 4.08Å; L49-Q77 HydrophobicContact CD2-CB 3.85Å; L49-Q77 HydrophobicContact CG-CB 4.45Å; L49-Q77 PolarHBondContact O-NE2 3.46Å; L49-L78 HydrophobicContact CD1-CD2 4.2Å; L49-L78 HydrophobicContact CD1-CG 4.1Å; L49-F442 HydrophobicContact CD1-CD2 4.37Å; L49-F442 HydrophobicContact CD1-CE2 3.38Å; L49-F442 HydrophobicContact CD1-CZ 3.54Å; L49-F442 HydrophobicContact CG-CE2 3.85Å; L49-F442 HydrophobicContact CG-CZ 4.4Å; L49-S471 PolarHBondContact N-O 3.09Å
50D96.6Very high96.3Very high105 Ų10533 Ų3356%0.56119%0.186SC*.  trans50.651.2176.8-163.234.7000113.1L40 S48 T472L40-D50 HydrophobicContact CD1-CB 3.71Å; L40-D50 HydrophobicContact CG-CB 4.17Å; S48-D50 VanDerWaalsContact C-N 3.33Å; S48-D50 PolarHBondContact OG-N 3.46Å; S48-D50 VanDerWaalsContact OG-N 3.16Å; D50-T472 PolarHBondContact N-O 3.06Å; D50-T472 VanDerWaalsContact N-O 3.15Å
51N95.6Very high95.9Very high13 Ų1332.2 Ų32.27%0.0719%0.186CC..  trans-140.268.6-177.3-168.9-3.5000111.2L49 D53 A54 T472L49-N51 PolarHBondContact O-N 2.91Å; N51-D53 PolarHBondContact O-N 2.63Å; N51-A54 HydrophobicContact CB-CB 4.38Å; N51-A54 WeakPolarHBondContact O-CB 3.14Å; N51-A54 PolarHBondContact O-N 3.45Å; N51-A54 VanDerWaalsContact O-N 3.15Å; N51-A54 PolarHBondContact OD1-N 3.13Å; N51-T472 PolarHBondContact N-O 2.72Å; N51-T472 WeakPolarHBondContact O-CB 3.19Å
52P94.9Very high95.6Very high56 Ų5633 Ų3336%0.36418%0.181SC..THydrogen-bonded Turntrans-59.5-33.9176.724.3-33.2000112.6A54 F55 H473P52-A54 PolarHBondContact O-N 3.45Å; P52-A54 VanDerWaalsContact O-N 3.09Å; P52-F55 WeakPolarHBondContact O-CB 3.21Å; P52-F55 PolarHBondContact O-N 2.88Å; P52-H473 HydrophobicContact CB-CB 4.29Å
53D93Very high95Very high109 Ų10932.4 Ų32.458%0.58318%0.179SC*.THydrogen-bonded Turntrans-62.3-18.1177.7-67.5-28.9000114N51 F55 H56 S57N51-D53 PolarHBondContact O-N 2.63Å; D53-F55 PolarHBondContact O-N 2.9Å; D53-H56 PolarHBondContact O-N 3.43Å; D53-S57 PolarHBondContact O-N 3.31Å; D53-S57 PolarHBondContact O-OG 3Å
54A94.6Very high94.3Very high0 Ų034.3 Ų34.30%020%0.197CC..Hα-helixtrans-57.9-32.5171.400000111.1N51 P52 H56 S57 F58 V70 T472N51-A54 HydrophobicContact CB-CB 4.38Å; N51-A54 WeakPolarHBondContact O-CB 3.14Å; N51-A54 PolarHBondContact O-N 3.45Å; N51-A54 VanDerWaalsContact O-N 3.15Å; N51-A54 PolarHBondContact OD1-N 3.13Å; P52-A54 PolarHBondContact O-N 3.45Å; P52-A54 VanDerWaalsContact O-N 3.09Å; A54-H56 PolarHBondContact O-N 3.12Å; A54-S57 PolarHBondContact O-N 3.42Å; A54-F58 HydrophobicContact CB-CD2 4.37Å; A54-F58 HydrophobicContact CB-CE2 4.49Å; A54-F58 VanDerWaalsContact O-CD2 3.23Å; A54-F58 WeakPolarHBondContact O-CD2 3.28Å; A54-F58 PolarHBondContact O-N 3.26Å; A54-V70 HydrophobicContact CB-CG1 3.99Å; A54-T472 HydrophobicContact CB-CG2 3.65Å
55F96Very high93.8Very high0 Ų039 Ų390%021%0.211CC..Hα-helixtrans-56.8-51.1177.7-173.2-94.5000111.6P52 D53 F58 Y59 L348 G445 L480 Q483 L484 M487P52-F55 WeakPolarHBondContact O-CB 3.21Å; P52-F55 PolarHBondContact O-N 2.88Å; D53-F55 PolarHBondContact O-N 2.9Å; F55-F58 PolarHBondContact O-N 3.27Å; F55-Y59 HydrophobicContact CD1-CD2 4.48Å; F55-Y59 AromaticContact CD2-CD2 3.72Å; F55-Y59 HydrophobicContact CD2-CD2 3.72Å; F55-Y59 AromaticContact CD2-CE2 3.95Å; F55-Y59 HydrophobicContact CD2-CE2 3.95Å; F55-Y59 AromaticContact CE2-CD2 3.84Å; F55-Y59 HydrophobicContact CE2-CD2 3.84Å; F55-Y59 HydrophobicContact CE2-CE2 4.12Å; F55-Y59 HydrophobicContact CG-CD2 4.07Å; F55-Y59 HydrophobicContact CZ-CD2 4.29Å; F55-Y59 WeakPolarHBondContact O-CB 3.24Å; F55-Y59 VanDerWaalsContact O-CD2 3.23Å; F55-Y59 WeakPolarHBondContact O-CD2 3.48Å; F55-Y59 PolarHBondContact O-N 3.45Å; F55-L348 HydrophobicContact CE2-CD1 4.33Å; F55-L348 HydrophobicContact CE2-CD2 4.15Å; F55-L348 HydrophobicContact CZ-CD1 3.86Å; F55-L348 HydrophobicContact CZ-CD2 4.23Å; F55-G445 WeakPolarHBondContact CD2-O 3.28Å; F55-L480 HydrophobicContact CE2-CD1 3.92Å; F55-L480 HydrophobicContact CZ-CD1 3.86Å; F55-Q483 HydrophobicContact CD1-CB 3.6Å; F55-Q483 HydrophobicContact CD1-CG 4.29Å; F55-Q483 HydrophobicContact CE1-CB 3.61Å; F55-Q483 HydrophobicContact CG-CB 4.34Å; F55-Q483 HydrophobicContact CZ-CB 4.36Å; F55-L484 HydrophobicContact CE1-CD2 4.31Å; F55-L484 HydrophobicContact CE1-CG 4.47Å; F55-L484 HydrophobicContact CZ-CD2 3.98Å; F55-L484 HydrophobicContact CZ-CG 4.21Å; F55-M487 HydrophobicContact CD1-CE 4.12Å; F55-M487 HydrophobicContact CE1-CE 3.32Å; F55-M487 HydrophobicContact CZ-CE 3.89Å
56H94.2Very high93.3Very high26 Ų2642 Ų4212%0.1223%0.227CC..Hα-helixtrans-68.6-36.7176.4-61162.2000112.2D53 A54 F58 S60 K63 Q483D53-H56 PolarHBondContact O-N 3.43Å; A54-H56 PolarHBondContact O-N 3.12Å; H56-F58 PolarHBondContact O-N 3.44Å; H56-S60 WeakPolarHBondContact O-CA 3.4Å; H56-S60 WeakPolarHBondContact O-CB 3.44Å; H56-S60 PolarHBondContact O-N 3.24Å; H56-K63 HydrophobicContact CB-CD 3.94Å; H56-Q483 PolarHBondContact NE2-O 2.97Å
57S93.9Very high93Very high8 Ų843.4 Ų43.46%0.05623%0.233CC..Hα-helixtrans-61.5-33.2177.9-56.20000112.9D53 A54D53-S57 PolarHBondContact O-N 3.31Å; D53-S57 PolarHBondContact O-OG 3Å; A54-S57 PolarHBondContact O-N 3.42Å
58F94.8Very high92.7Very high5 Ų548 Ų482%0.02226%0.257CS..Hα-helixtrans-86.5-42178.8-84.4-97.5000113.5A54 F55 H56 K67 V70 M71 L74 D99 I444A54-F58 HydrophobicContact CB-CD2 4.37Å; A54-F58 HydrophobicContact CB-CE2 4.49Å; A54-F58 VanDerWaalsContact O-CD2 3.23Å; A54-F58 WeakPolarHBondContact O-CD2 3.28Å; A54-F58 PolarHBondContact O-N 3.26Å; F55-F58 PolarHBondContact O-N 3.27Å; H56-F58 PolarHBondContact O-N 3.44Å; F58-K67 HydrophobicContact CD1-CD 4.24Å; F58-K67 HydrophobicContact CD1-CG 4.09Å; F58-K67 HydrophobicContact CE1-CG 4.23Å; F58-K67 HydrophobicContact CG-CG 4.41Å; F58-K67 VanDerWaalsContact O-CE 3.23Å; F58-K67 WeakPolarHBondContact O-CE 3.49Å; F58-K67 PolarHBondContact O-NZ 2.99Å; F58-V70 HydrophobicContact CD2-CG1 4.4Å; F58-V70 HydrophobicContact CE2-CB 4.49Å; F58-V70 HydrophobicContact CE2-CG1 3.77Å; F58-M71 HydrophobicContact CE1-CG 3.62Å; F58-M71 HydrophobicContact CE1-SD 4.04Å; F58-M71 HydrophobicContact CE2-CG 4.34Å; F58-M71 HydrophobicContact CZ-CB 4.47Å; F58-M71 HydrophobicContact CZ-CG 3.33Å; F58-M71 HydrophobicContact CZ-SD 4.36Å; F58-L74 HydrophobicContact CE2-CD1 3.65Å; F58-L74 HydrophobicContact CZ-CD1 3.87Å; F58-D99 HydrophobicContact CE1-CB 4.41Å; F58-I444 HydrophobicContact CB-CG2 4.27Å; F58-I444 HydrophobicContact CD1-CD1 4.47Å; F58-I444 HydrophobicContact CD1-CG2 3.67Å; F58-I444 HydrophobicContact CD2-CG2 3.79Å; F58-I444 HydrophobicContact CE1-CD1 3.92Å; F58-I444 HydrophobicContact CE1-CG2 3.79Å; F58-I444 HydrophobicContact CE2-CG2 3.89Å; F58-I444 HydrophobicContact CG-CG2 3.63Å; F58-I444 HydrophobicContact CZ-CD1 4.37Å; F58-I444 HydrophobicContact CZ-CG2 3.86Å
59Y95.3Very high92.5Very high6 Ų650.9 Ų50.92%0.02428%0.276CS..Hα-helixtrans-107.7-23.6-167-57.6-60.4000114.3F55 Y97 R137 H347 L348 I444F55-Y59 HydrophobicContact CD1-CD2 4.48Å; F55-Y59 AromaticContact CD2-CD2 3.72Å; F55-Y59 HydrophobicContact CD2-CD2 3.72Å; F55-Y59 AromaticContact CD2-CE2 3.95Å; F55-Y59 HydrophobicContact CD2-CE2 3.95Å; F55-Y59 AromaticContact CE2-CD2 3.84Å; F55-Y59 HydrophobicContact CE2-CD2 3.84Å; F55-Y59 HydrophobicContact CE2-CE2 4.12Å; F55-Y59 HydrophobicContact CG-CD2 4.07Å; F55-Y59 HydrophobicContact CZ-CD2 4.29Å; F55-Y59 WeakPolarHBondContact O-CB 3.24Å; F55-Y59 VanDerWaalsContact O-CD2 3.23Å; F55-Y59 WeakPolarHBondContact O-CD2 3.48Å; F55-Y59 PolarHBondContact O-N 3.45Å; Y59-Y97 WeakPolarHBondContact CD1-OH 2.88Å; Y59-Y97 HydrophobicContact CE1-CE1 4.35Å; Y59-Y97 HydrophobicContact CE1-CE2 4.18Å; Y59-Y97 AromaticContact CE1-CZ 3.71Å; Y59-Y97 VanDerWaalsContact CE1-OH 3.28Å; Y59-Y97 WeakPolarHBondContact CE1-OH 3.29Å; Y59-R137 HydrophobicContact CE2-CB 4.21Å; Y59-R137 PolarHBondContact OH-N 2.9Å; Y59-H347 WeakPolarHBondContact O-CB 3.5Å; Y59-L348 HydrophobicContact CD1-CD1 4.15Å; Y59-L348 HydrophobicContact CD1-CG 4.04Å; Y59-L348 HydrophobicContact CD2-CD1 4.15Å; Y59-L348 HydrophobicContact CD2-CG 4.23Å; Y59-L348 HydrophobicContact CE1-CG 4.19Å; Y59-L348 HydrophobicContact CE2-CG 4.38Å; Y59-L348 HydrophobicContact CG-CD1 3.82Å; Y59-L348 HydrophobicContact CG-CG 4.08Å; Y59-I444 PolarHBondContact OH-O 3Å; Y59-I444 VanDerWaalsContact OH-O 3.09Å
60S93.9Very high92.4Very high6 Ų651.9 Ų51.94%0.04228%0.282CS..  trans-71.3131176.31790000110.7H56 H62 K63 M487H56-S60 WeakPolarHBondContact O-CA 3.4Å; H56-S60 WeakPolarHBondContact O-CB 3.44Å; H56-S60 PolarHBondContact O-N 3.24Å; S60-H62 PolarHBondContact O-N 2.84Å; S60-H62 PolarHBondContact OG-N 3.08Å; S60-K63 PolarHBondContact O-N 3.01Å; S60-M487 WeakPolarHBondContact CB-O 3.25Å; S60-M487 PolarHBondContact OG-O 2.92Å
61P89.6Confident92.3Very high65 Ų6547 Ų4742%0.42226%0.256SS..G310 helixtrans-63.2-23.3174.226.6-33.8000112.4
62H89.2Confident92.3Very high117 Ų11751.3 Ų51.354%0.54228%0.276SS..G310 helixtrans-81.2-18.7-178.5-59.3-67.6000113.6S60S60-H62 PolarHBondContact O-N 2.84Å; S60-H62 PolarHBondContact OG-N 3.08Å
63K87.1Confident92.3Very high37 Ų3753.9 Ų53.916%0.16128%0.278CS..G310 helixtrans-110.314.7-175-62-165.7178.7-164.90114.4H56 S60 Q65 L66 D491H56-K63 HydrophobicContact CB-CD 3.94Å; S60-K63 PolarHBondContact O-N 3.01Å; K63-Q65 PolarHBondContact O-N 3.29Å; K63-L66 HydrophobicContact CB-CD1 4.34Å; K63-L66 HydrophobicContact CD-CD1 4.26Å; K63-L66 HydrophobicContact CG-CD1 4.41Å; K63-L66 WeakPolarHBondContact O-CB 3.42Å; K63-L66 PolarHBondContact O-N 3.14Å; K63-D491 WeakPolarHBondContact CE-OD1 3.43Å; K63-D491 IonicContact NZ-OD1 3.44Å; K63-D491 PolarHBondContact NZ-OD1 3.09Å
64A82.4Confident92.5Very high53 Ų5348.7 Ų48.744%0.43825%0.25SS..G310 helixtrans-54.3-29.7-177.300000114L66 K67A64-L66 VanDerWaalsContact C-N 3.35Å; A64-K67 VanDerWaalsContact O-CB 3.32Å; A64-K67 WeakPolarHBondContact O-CB 3.32Å; A64-K67 PolarHBondContact O-N 2.96Å
65Q86.8Confident92.7Very high175 Ų17548.7 Ų48.782%0.81825%0.25SS*.G310 helixtrans-71.1-27178-59.1-60.1-26.100113.4K63 K67K63-Q65 PolarHBondContact O-N 3.29Å; Q65-K67 VanDerWaalsContact C-N 3.28Å
66L88.6Confident92.6Very high83 Ų8350.9 Ų50.944%0.43526%0.261SS..G310 helixtrans-80.3-11.9178.7-60.6178.6000112.5K63 A64 N68 P69 V70K63-L66 HydrophobicContact CB-CD1 4.34Å; K63-L66 HydrophobicContact CD-CD1 4.26Å; K63-L66 HydrophobicContact CG-CD1 4.41Å; K63-L66 WeakPolarHBondContact O-CB 3.42Å; K63-L66 PolarHBondContact O-N 3.14Å; A64-L66 VanDerWaalsContact C-N 3.35Å; L66-N68 PolarHBondContact O-N 3.21Å; L66-P69 VanDerWaalsContact O-CD 3.23Å; L66-P69 WeakPolarHBondContact O-CD 3.37Å; L66-P69 VanDerWaalsContact O-CG 3.26Å; L66-P69 WeakPolarHBondContact O-CG 3.48Å; L66-V70 VanDerWaalsContact O-CG2 3.24Å; L66-V70 WeakPolarHBondContact O-CG2 3.36Å; L66-V70 PolarHBondContact O-N 3.07Å
67K90.6Very high92.7Very high32 Ų3250.1 Ų50.114%0.13926%0.257CS..Hα-helixtrans-60.1-46.1-173.7-169.3-178.3-65.4-157.90113.2F58 A64 Q65 V70 M71 D99F58-K67 HydrophobicContact CD1-CD 4.24Å; F58-K67 HydrophobicContact CD1-CG 4.09Å; F58-K67 HydrophobicContact CE1-CG 4.23Å; F58-K67 HydrophobicContact CG-CG 4.41Å; F58-K67 VanDerWaalsContact O-CE 3.23Å; F58-K67 WeakPolarHBondContact O-CE 3.49Å; F58-K67 PolarHBondContact O-NZ 2.99Å; A64-K67 VanDerWaalsContact O-CB 3.32Å; A64-K67 WeakPolarHBondContact O-CB 3.32Å; A64-K67 PolarHBondContact O-N 2.96Å; Q65-K67 VanDerWaalsContact C-N 3.28Å; K67-V70 PolarHBondContact O-N 3.33Å; K67-M71 HydrophobicContact CD-CE 4.4Å; K67-M71 HydrophobicContact CG-CE 4.01Å; K67-M71 HydrophobicContact CG-CG 4.47Å; K67-M71 HydrophobicContact CG-SD 4.37Å; K67-M71 WeakPolarHBondContact O-CG 3.44Å; K67-M71 PolarHBondContact O-N 3.2Å; K67-D99 VanDerWaalsContact CD-OD2 3.26Å; K67-D99 WeakPolarHBondContact CD-OD2 3.35Å; K67-D99 IonicContact NZ-OD2 2.72Å; K67-D99 PolarHBondContact NZ-OD2 2.9Å
68N93.3Very high92.9Very high100 Ų10049.8 Ų49.854%0.53526%0.255SS..Hα-helixtrans-61.6-53.4-177.7-69.2-13.5000113.6L66 V70 M71 E72L66-N68 PolarHBondContact O-N 3.21Å; N68-V70 VanDerWaalsContact C-N 3.26Å; N68-V70 PolarHBondContact O-N 3.06Å; N68-M71 HydrophobicContact CB-CE 4.46Å; N68-M71 WeakPolarHBondContact O-CB 3.49Å; N68-M71 PolarHBondContact O-N 2.98Å; N68-M71 VanDerWaalsContact O-N 3.13Å; N68-M71 WeakPolarHBondContact OD1-CE 3.32Å; N68-E72 PolarHBondContact O-N 3.47Å
69P93.6Very high93Very high72 Ų7249.5 Ų49.547%0.46825%0.254SS..Hα-helixtrans-64.2-32.3178.123.5-33.4000112.4L66 R73L66-P69 VanDerWaalsContact O-CD 3.23Å; L66-P69 WeakPolarHBondContact O-CD 3.37Å; L66-P69 VanDerWaalsContact O-CG 3.26Å; L66-P69 WeakPolarHBondContact O-CG 3.48Å; P69-R73 PolarHBondContact O-N 3.19Å; P69-R73 VanDerWaalsContact O-N 3.1Å
70V95.6Very high93.1Very high21 Ų2149.2 Ų49.213%0.12725%0.253CS..Hα-helixtrans-65.7-44.7172.9176.80000110.7A54 F58 L66 K67 N68 E72 R73 L74A54-V70 HydrophobicContact CB-CG1 3.99Å; F58-V70 HydrophobicContact CD2-CG1 4.4Å; F58-V70 HydrophobicContact CE2-CB 4.49Å; F58-V70 HydrophobicContact CE2-CG1 3.77Å; L66-V70 VanDerWaalsContact O-CG2 3.24Å; L66-V70 WeakPolarHBondContact O-CG2 3.36Å; L66-V70 PolarHBondContact O-N 3.07Å; K67-V70 PolarHBondContact O-N 3.33Å; N68-V70 VanDerWaalsContact C-N 3.26Å; N68-V70 PolarHBondContact O-N 3.06Å; V70-E72 PolarHBondContact O-N 3.22Å; V70-R73 PolarHBondContact O-N 3.21Å; V70-L74 HydrophobicContact CG1-CD1 4.21Å; V70-L74 HydrophobicContact CG1-CG 4.2Å; V70-L74 VanDerWaalsContact O-CG 3.3Å; V70-L74 WeakPolarHBondContact O-CG 3.45Å; V70-L74 PolarHBondContact O-N 2.69Å
71M95.8Very high93.2Very high2 Ų249.2 Ų49.21%0.0125%0.252CS..Hα-helixtrans-57.9-44.5176-79.6-173.7-61.100112.5F58 K67 N68 L74 A75 D99 T102 L103 L106F58-M71 HydrophobicContact CE1-CG 3.62Å; F58-M71 HydrophobicContact CE1-SD 4.04Å; F58-M71 HydrophobicContact CE2-CG 4.34Å; F58-M71 HydrophobicContact CZ-CB 4.47Å; F58-M71 HydrophobicContact CZ-CG 3.33Å; F58-M71 HydrophobicContact CZ-SD 4.36Å; K67-M71 HydrophobicContact CD-CE 4.4Å; K67-M71 HydrophobicContact CG-CE 4.01Å; K67-M71 HydrophobicContact CG-CG 4.47Å; K67-M71 HydrophobicContact CG-SD 4.37Å; K67-M71 WeakPolarHBondContact O-CG 3.44Å; K67-M71 PolarHBondContact O-N 3.2Å; N68-M71 HydrophobicContact CB-CE 4.46Å; N68-M71 WeakPolarHBondContact O-CB 3.49Å; N68-M71 PolarHBondContact O-N 2.98Å; N68-M71 VanDerWaalsContact O-N 3.13Å; N68-M71 WeakPolarHBondContact OD1-CE 3.32Å; M71-L74 PolarHBondContact O-N 3.36Å; M71-A75 WeakPolarHBondContact O-CB 3.11Å; M71-A75 PolarHBondContact O-N 2.93Å; M71-D99 HydrophobicContact SD-CB 4.19Å; M71-T102 HydrophobicContact CE-CG2 3.92Å; M71-T102 HydrophobicContact SD-CG2 4.04Å; M71-L103 HydrophobicContact CB-CD1 4.42Å; M71-L103 VanDerWaalsContact O-CD1 3.31Å; M71-L103 WeakPolarHBondContact O-CD1 3.38Å; M71-L106 HydrophobicContact CB-CD1 3.91Å
72E95.4Very high93.6Very high104 Ų10446.2 Ų46.249%0.48623%0.232SC..Hα-helixtrans-60-46176.4-73176.3-174.300111.5N68 V70 A75 E76 L106N68-E72 PolarHBondContact O-N 3.47Å; V70-E72 PolarHBondContact O-N 3.22Å; E72-A75 PolarHBondContact O-N 3.42Å; E72-E76 WeakPolarHBondContact O-CG 3.41Å; E72-E76 PolarHBondContact O-N 2.89Å; E72-L106 HydrophobicContact CG-CD1 4.16Å; E72-L106 HydrophobicContact CG-CD2 4.28Å
73R94.9Very high93.8Very high110 Ų11041.4 Ų41.442%0.41521%0.213SC..Hα-helixtrans-60.3-46174.8163.6162.3-179.6-166.60.6112.3F9 P69 V70 A75 E76 Q77F9-R73 HydrophobicContact CE2-CG 4.05Å; F9-R73 HydrophobicContact CZ-CB 4.3Å; F9-R73 HydrophobicContact CZ-CG 3.76Å; P69-R73 PolarHBondContact O-N 3.19Å; P69-R73 VanDerWaalsContact O-N 3.1Å; V70-R73 PolarHBondContact O-N 3.21Å; R73-A75 VanDerWaalsContact C-N 3.31Å; R73-A75 PolarHBondContact O-N 3.32Å; R73-E76 PolarHBondContact O-N 2.92Å; R73-Q77 WeakPolarHBondContact O-CG 3.27Å; R73-Q77 PolarHBondContact O-N 3.43Å
74L97.4Very high94.2Very high0 Ų042.7 Ų42.70%022%0.224CC..Hα-helixtrans-62.9-40.1178.1-64-177.7000111.2L49 F58 V70 M71 E76 Q77 L78 L103 F442 T472L49-L74 HydrophobicContact CB-CD2 4.35Å; L49-L74 HydrophobicContact CD1-CB 4.38Å; L49-L74 HydrophobicContact CD1-CD2 3.76Å; F58-L74 HydrophobicContact CE2-CD1 3.65Å; F58-L74 HydrophobicContact CZ-CD1 3.87Å; V70-L74 HydrophobicContact CG1-CD1 4.21Å; V70-L74 HydrophobicContact CG1-CG 4.2Å; V70-L74 VanDerWaalsContact O-CG 3.3Å; V70-L74 WeakPolarHBondContact O-CG 3.45Å; V70-L74 PolarHBondContact O-N 2.69Å; M71-L74 PolarHBondContact O-N 3.36Å; L74-E76 VanDerWaalsContact C-N 3.35Å; L74-E76 PolarHBondContact O-N 3.46Å; L74-Q77 PolarHBondContact O-N 3.24Å; L74-L78 WeakPolarHBondContact O-CB 3.43Å; L74-L78 VanDerWaalsContact O-CG 3.29Å; L74-L78 WeakPolarHBondContact O-CG 3.48Å; L74-L78 PolarHBondContact O-N 2.91Å; L74-L103 HydrophobicContact CB-CD1 4.08Å; L74-F442 HydrophobicContact CD1-CE1 4.36Å; L74-F442 HydrophobicContact CD1-CZ 4.28Å; L74-T472 HydrophobicContact CD1-CG2 3.84Å; L74-T472 HydrophobicContact CD2-CG2 3.99Å
75A97.8Very high94.8Very high0 Ų042.3 Ų42.30%021%0.214CC..Hα-helixtrans-61.5-43.5177.800000112.2M71 E72 R73 L78 A79 L103 L106 V107 K110M71-A75 WeakPolarHBondContact O-CB 3.11Å; M71-A75 PolarHBondContact O-N 2.93Å; E72-A75 PolarHBondContact O-N 3.42Å; R73-A75 VanDerWaalsContact C-N 3.31Å; R73-A75 PolarHBondContact O-N 3.32Å; A75-L78 PolarHBondContact O-N 3.49Å; A75-A79 WeakPolarHBondContact O-CB 3.41Å; A75-A79 PolarHBondContact O-N 2.77Å; A75-L103 HydrophobicContact CB-CD1 4Å; A75-L106 HydrophobicContact CB-CB 3.56Å; A75-V107 HydrophobicContact CB-CG2 3.84Å; A75-K110 HydrophobicContact CB-CG 4.5Å
76E95.2Very high95.2Very high47 Ų4739 Ų3922%0.2220%0.197CC..Hα-helixtrans-60.3-48.9174.6-78.1178.2-178.800111.9F9 P10 E72 R73 L74 L78 A79 T80 K110F9-E76 WeakPolarHBondContact CE1-OE2 3.38Å; P10-E76 HydrophobicContact CG-CB 3.75Å; P10-E76 HydrophobicContact CG-CG 4.28Å; E72-E76 WeakPolarHBondContact O-CG 3.41Å; E72-E76 PolarHBondContact O-N 2.89Å; R73-E76 PolarHBondContact O-N 2.92Å; L74-E76 VanDerWaalsContact C-N 3.35Å; L74-E76 PolarHBondContact O-N 3.46Å; E76-L78 PolarHBondContact O-N 3Å; E76-A79 PolarHBondContact O-N 2.89Å; E76-T80 WeakPolarHBondContact O-CG2 3.45Å; E76-T80 PolarHBondContact O-N 2.93Å; E76-K110 HydrophobicContact CG-CD 3.83Å; E76-K110 HydrophobicContact CG-CG 4.25Å; E76-K110 IonicContact OE1-NZ 3.98Å; E76-K110 PolarHBondContact OE1-NZ 3.29Å
77Q96.6Very high95.6Very high9 Ų935.1 Ų35.14%0.04218%0.177CC..Hα-helixtrans-61.4-42.7178.3-66.5-179.4-92.400112.1F9 A38 L49 R73 L74 A79 T80 L81F9-Q77 HydrophobicContact CE2-CG 3.84Å; F9-Q77 HydrophobicContact CZ-CG 4.48Å; A38-Q77 HydrophobicContact CB-CB 4.38Å; A38-Q77 HydrophobicContact CB-CG 3.87Å; A38-Q77 WeakPolarHBondContact O-CB 3.18Å; A38-Q77 VanDerWaalsContact O-CG 3.27Å; A38-Q77 WeakPolarHBondContact O-CG 3.4Å; A38-Q77 PolarHBondContact O-NE2 3.45Å; L49-Q77 HydrophobicContact CD1-CB 4.08Å; L49-Q77 HydrophobicContact CD2-CB 3.85Å; L49-Q77 HydrophobicContact CG-CB 4.45Å; L49-Q77 PolarHBondContact O-NE2 3.46Å; R73-Q77 WeakPolarHBondContact O-CG 3.27Å; R73-Q77 PolarHBondContact O-N 3.43Å; L74-Q77 PolarHBondContact O-N 3.24Å; Q77-A79 VanDerWaalsContact C-N 3.33Å; Q77-A79 PolarHBondContact O-N 3.37Å; Q77-T80 PolarHBondContact O-N 2.87Å; Q77-T80 VanDerWaalsContact O-N 3.16Å; Q77-T80 PolarHBondContact O-OG1 3.33Å; Q77-L81 PolarHBondContact O-N 3.42Å
78L97.6Very high95.9Very high1 Ų137.1 Ų37.11%0.00518%0.184CC..Hα-helixtrans-63.2-37.9175.7-72.3171.3000112.7Y47 L49 L74 A75 E76 T80 L81 C82 V107 F442Y47-L78 HydrophobicContact CE2-CD2 3.7Å; Y47-L78 WeakPolarHBondContact OH-CD2 3.15Å; L49-L78 HydrophobicContact CD1-CD2 4.2Å; L49-L78 HydrophobicContact CD1-CG 4.1Å; L74-L78 WeakPolarHBondContact O-CB 3.43Å; L74-L78 VanDerWaalsContact O-CG 3.29Å; L74-L78 WeakPolarHBondContact O-CG 3.48Å; L74-L78 PolarHBondContact O-N 2.91Å; A75-L78 PolarHBondContact O-N 3.49Å; E76-L78 PolarHBondContact O-N 3Å; L78-T80 VanDerWaalsContact C-N 3.31Å; L78-T80 PolarHBondContact O-N 3.01Å; L78-L81 WeakPolarHBondContact O-CB 3.32Å; L78-L81 PolarHBondContact O-N 3.16Å; L78-C82 PolarHBondContact O-N 2.95Å; L78-C82 PolarHBondContact O-SG 3.13Å; L78-C82 VanDerWaalsContact O-SG 3.37Å; L78-V107 HydrophobicContact CB-CG2 4.14Å; L78-V107 HydrophobicContact CD1-CG2 3.73Å; L78-F442 HydrophobicContact CD1-CB 4.37Å; L78-F442 HydrophobicContact CD1-CD1 3.7Å; L78-F442 HydrophobicContact CD1-CD2 4.36Å; L78-F442 HydrophobicContact CD1-CE1 4Å; L78-F442 HydrophobicContact CD1-CG 3.87Å; L78-F442 HydrophobicContact CD1-CZ 4.44Å; L78-F442 HydrophobicContact CD2-CB 4.07Å; L78-F442 HydrophobicContact CD2-CD1 4.4Å; L78-F442 HydrophobicContact CD2-CD2 3.6Å; L78-F442 HydrophobicContact CD2-CE2 4.07Å; L78-F442 HydrophobicContact CD2-CG 3.76Å; L78-F442 HydrophobicContact CG-CD2 4.44Å; L78-F442 HydrophobicContact CG-CG 4.4Å
79A96.9Very high96.1Very high0 Ų032.5 Ų32.50%016%0.159CC..Hα-helixtrans-64.8-36.7174.700000111.4A75 E76 Q77 L81 C82 A83 K110 L111 Y114A75-A79 WeakPolarHBondContact O-CB 3.41Å; A75-A79 PolarHBondContact O-N 2.77Å; E76-A79 PolarHBondContact O-N 2.89Å; Q77-A79 VanDerWaalsContact C-N 3.33Å; Q77-A79 PolarHBondContact O-N 3.37Å; A79-L81 VanDerWaalsContact C-N 3.33Å; A79-L81 PolarHBondContact O-N 2.67Å; A79-C82 PolarHBondContact O-N 3.06Å; A79-A83 WeakPolarHBondContact O-CB 3.23Å; A79-A83 PolarHBondContact O-N 3.47Å; A79-K110 HydrophobicContact CB-CB 3.59Å; A79-L111 HydrophobicContact CB-CD2 4.25Å; A79-Y114 HydrophobicContact CB-CD2 3.87Å; A79-Y114 HydrophobicContact CB-CE2 3.71Å
80T96.3Very high96.2Very high0 Ų030.5 Ų30.50%015%0.149CC..Hα-helixtrans-62.3-37.1174.370.10000113.3P10 N36 A38 E76 Q77 L78 A83 T84P10-T80 HydrophobicContact CB-CG2 4.35Å; P10-T80 HydrophobicContact CG-CG2 4.11Å; N36-T80 HydrophobicContact CB-CG2 4.47Å; N36-T80 VanDerWaalsContact O-CB 3.28Å; N36-T80 WeakPolarHBondContact O-CB 3.3Å; A38-T80 HydrophobicContact CB-CG2 4Å; A38-T80 PolarHBondContact N-OG1 3.49Å; E76-T80 WeakPolarHBondContact O-CG2 3.45Å; E76-T80 PolarHBondContact O-N 2.93Å; Q77-T80 PolarHBondContact O-N 2.87Å; Q77-T80 VanDerWaalsContact O-N 3.16Å; Q77-T80 PolarHBondContact O-OG1 3.33Å; L78-T80 VanDerWaalsContact C-N 3.31Å; L78-T80 PolarHBondContact O-N 3.01Å; T80-A83 PolarHBondContact O-N 2.96Å; T80-T84 VanDerWaalsContact O-CB 3.31Å; T80-T84 WeakPolarHBondContact O-CB 3.35Å; T80-T84 PolarHBondContact O-N 3.1Å; T80-T84 PolarHBondContact O-OG1 2.99Å
81L96.9Very high96.4Very high6 Ų629.6 Ų29.63%0.03114%0.144CC..Hα-helixtrans-60.4-50.7172.9172.868.4000110.6F39 Y47 Q77 L78 A79 A83 T84 L85F39-L81 HydrophobicContact CD1-CB 3.94Å; F39-L81 HydrophobicContact CD1-CD1 4.3Å; F39-L81 HydrophobicContact CD2-CD1 4.02Å; F39-L81 HydrophobicContact CE1-CB 4.03Å; F39-L81 HydrophobicContact CE1-CD1 3.94Å; F39-L81 HydrophobicContact CE2-CD1 3.61Å; F39-L81 HydrophobicContact CG-CB 4.38Å; F39-L81 HydrophobicContact CG-CD1 4.35Å; F39-L81 HydrophobicContact CZ-CD1 3.57Å; Y47-L81 HydrophobicContact CD1-CD2 3.65Å; Y47-L81 HydrophobicContact CD2-CD2 3.93Å; Y47-L81 HydrophobicContact CE1-CD2 3.46Å; Y47-L81 VanDerWaalsContact CE1-CD2 3.46Å; Y47-L81 HydrophobicContact CE2-CD2 3.76Å; Y47-L81 HydrophobicContact CG-CD2 3.87Å; Q77-L81 PolarHBondContact O-N 3.42Å; L78-L81 WeakPolarHBondContact O-CB 3.32Å; L78-L81 PolarHBondContact O-N 3.16Å; A79-L81 VanDerWaalsContact C-N 3.33Å; A79-L81 PolarHBondContact O-N 2.67Å; L81-A83 VanDerWaalsContact C-N 3.34Å; L81-A83 PolarHBondContact O-N 3.36Å; L81-T84 PolarHBondContact O-N 3.41Å; L81-L85 HydrophobicContact CD1-CD1 3.79Å; L81-L85 HydrophobicContact CD1-CG 4.37Å; L81-L85 HydrophobicContact CG-CD1 4.16Å; L81-L85 WeakPolarHBondContact O-CB 3.22Å; L81-L85 VanDerWaalsContact O-CG 3.31Å; L81-L85 WeakPolarHBondContact O-CG 3.43Å; L81-L85 PolarHBondContact O-N 2.94Å; L81-L85 VanDerWaalsContact O-N 3.09Å
82C96.9Very high96.5Very high1 Ų129.7 Ų29.71%0.00714%0.144CC..Hα-helixtrans-61.6-43.7179.3-62.70000111.4L78 A79 L85 K86 E87 L111L78-C82 PolarHBondContact O-N 2.95Å; L78-C82 PolarHBondContact O-SG 3.13Å; L78-C82 VanDerWaalsContact O-SG 3.37Å; A79-C82 PolarHBondContact O-N 3.06Å; C82-L85 CarbonylContact O-C 3.42Å; C82-L85 PolarHBondContact O-N 3.43Å; C82-K86 PolarHBondContact O-N 3.19Å; C82-E87 WeakPolarHBondContact CB-O 3.29Å; C82-E87 PolarHBondContact O-N 3.08Å; C82-L111 HydrophobicContact CB-CD2 3.39Å
83A95Very high96.7Very high17 Ų1726.9 Ų26.914%0.1413%0.129CC..Hα-helixtrans-62.6-45.7178.300000112.3A79 T80 L81 L85 K86 Y114 M121A79-A83 WeakPolarHBondContact O-CB 3.23Å; A79-A83 PolarHBondContact O-N 3.47Å; T80-A83 PolarHBondContact O-N 2.96Å; L81-A83 VanDerWaalsContact C-N 3.34Å; L81-A83 PolarHBondContact O-N 3.36Å; A83-L85 PolarHBondContact O-N 2.86Å; A83-K86 PolarHBondContact O-N 2.8Å; A83-Y114 HydrophobicContact CB-CD1 3.77Å; A83-Y114 HydrophobicContact CB-CD2 4.36Å; A83-Y114 HydrophobicContact CB-CE1 3.93Å; A83-Y114 HydrophobicContact CB-CE2 4.49Å; A83-Y114 HydrophobicContact CB-CG 4.02Å; A83-M121 HydrophobicContact CB-CE 3.82Å
84T94.9Very high96.8Very high64 Ų6423 Ų2339%0.39312%0.115SC..Hα-helixtrans-57.9-39.1176.4-60.30000111.4F39 T80 L81 K86F39-T84 HydrophobicContact CZ-CG2 4.38Å; T80-T84 VanDerWaalsContact O-CB 3.31Å; T80-T84 WeakPolarHBondContact O-CB 3.35Å; T80-T84 PolarHBondContact O-N 3.1Å; T80-T84 PolarHBondContact O-OG1 2.99Å; L81-T84 PolarHBondContact O-N 3.41Å; T84-K86 VanDerWaalsContact C-N 3.32Å
85L95.1Very high96.7Very high44 Ų4425 Ų2523%0.2314%0.135CC..THydrogen-bonded Turntrans-85.1-3.4179.1-64.3178.6000113.8L81 C82 A83 E87 K127 R438 I468L81-L85 HydrophobicContact CD1-CD1 3.79Å; L81-L85 HydrophobicContact CD1-CG 4.37Å; L81-L85 HydrophobicContact CG-CD1 4.16Å; L81-L85 WeakPolarHBondContact O-CB 3.22Å; L81-L85 VanDerWaalsContact O-CG 3.31Å; L81-L85 WeakPolarHBondContact O-CG 3.43Å; L81-L85 PolarHBondContact O-N 2.94Å; L81-L85 VanDerWaalsContact O-N 3.09Å; C82-L85 CarbonylContact O-C 3.42Å; C82-L85 PolarHBondContact O-N 3.43Å; A83-L85 PolarHBondContact O-N 2.86Å; L85-E87 HydrophobicContact CB-CG 3.9Å; L85-E87 PolarHBondContact O-N 3.15Å; L85-K127 PolarHBondContact O-NZ 3.18Å; L85-R438 VanDerWaalsContact CB-NH1 3.33Å; L85-I468 HydrophobicContact CD1-CD1 3.99Å
86K95.1Very high96.5Very high106 Ų10630.6 Ų30.646%0.46116%0.161SC..THydrogen-bonded Turntrans49.644-169.3-59.8-168.1171-149.20112.6C82 A83 T84 D118 G122 K127C82-K86 PolarHBondContact O-N 3.19Å; A83-K86 PolarHBondContact O-N 2.8Å; T84-K86 VanDerWaalsContact C-N 3.32Å; K86-D118 IonicContact NZ-OD2 3.42Å; K86-G122 PolarHBondContact O-N 2.9Å; K86-K127 PolarHBondContact O-NZ 3.03Å
87E96Very high96.4Very high1 Ų130 Ų301%0.00516%0.157CC..  trans-103.5138.4175.8-68.4-62.9154.100110.1C82 L85 M121 K127 S130 R438 M440C82-E87 WeakPolarHBondContact CB-O 3.29Å; C82-E87 PolarHBondContact O-N 3.08Å; L85-E87 HydrophobicContact CB-CG 3.9Å; L85-E87 PolarHBondContact O-N 3.15Å; E87-M121 WeakPolarHBondContact O-CG 3.35Å; E87-K127 IonicContact OE1-NZ 3.38Å; E87-K127 PolarHBondContact OE1-NZ 3.11Å; E87-S130 WeakPolarHBondContact OE2-CB 3.47Å; E87-S130 PolarHBondContact OE2-OG 3.16Å; E87-R438 WeakPolarHBondContact OE1-CD 3.37Å; E87-M440 HydrophobicContact CB-CE 3.97Å; E87-M440 HydrophobicContact CG-CE 4.22Å
88Y97Very high96.3Very high75 Ų7537.6 Ų37.629%0.29419%0.19SC..  trans-123.776167.6-176.1-99.9000107.5Q108 L111 D112 K115Y88-Q108 PolarHBondContact OH-NE2 3.37Å; Y88-Q108 VanDerWaalsContact OH-NE2 3.08Å; Y88-L111 HydrophobicContact CD2-CB 4.04Å; Y88-L111 HydrophobicContact CE2-CB 3.87Å; Y88-D112 WeakPolarHBondContact CE2-OD1 3.42Å; Y88-D112 PolarHBondContact OH-OD1 2.87Å; Y88-K115 HydrophobicContact CD2-CB 3.79Å; Y88-K115 HydrophobicContact CD2-CD 4.39Å; Y88-K115 HydrophobicContact CD2-CG 4.09Å; Y88-K115 HydrophobicContact CE2-CB 3.79Å; Y88-K115 HydrophobicContact CE2-CG 4.11Å; Y88-K115 HydrophobicContact CG-CD 4.4Å; Y88-K115 HydrophobicContact CG-CG 4.48Å
89P97.3Very high96.2Very high2 Ų238.9 Ų38.91%0.01320%0.197CC..  trans-74.4154.5-169.931.6-37.2000112.1V91 L111 S130 L132 M440P89-V91 PolarHBondContact O-N 3.4Å; P89-L111 HydrophobicContact CG-CD1 4.25Å; P89-S130 WeakPolarHBondContact CA-O 3.41Å; P89-L132 HydrophobicContact CB-CB 3.94Å; P89-L132 HydrophobicContact CG-CB 3.68Å; P89-L132 HydrophobicContact CG-CD2 4.5Å; P89-M440 HydrophobicContact CB-CE 3.47Å; P89-M440 VanDerWaalsContact CB-CE 3.47Å; P89-M440 HydrophobicContact CG-CE 3.51Å
90A97.7Very high96.3Very high31 Ų3138.9 Ų38.926%0.25620%0.197SC..EExtended strand (participates in β ladder)trans-70113.8165.900000109.8S130 Q131 L132 Y403A90-S130 PolarHBondContact N-O 2.91Å; A90-Q131 WeakPolarHBondContact O-CA 3.47Å; A90-L132 PolarHBondContact O-N 2.96Å; A90-Y403 HydrophobicContact CB-CD1 3.91Å; A90-Y403 HydrophobicContact CB-CE1 3.68Å
91V98.5Very high96.3Very high2 Ų240.2 Ų40.21%0.01221%0.208CC..EExtended strand (participates in β ladder)trans-79.9126.2-176.7-172.30000110.9P89 A104 V107 L111 L132 Y403 I404P89-V91 PolarHBondContact O-N 3.4Å; V91-A104 HydrophobicContact CG1-CB 3.85Å; V91-V107 HydrophobicContact CG2-CG1 4.39Å; V91-L111 HydrophobicContact CG2-CD1 3.83Å; V91-L132 CarbonylContact C-O 3.59Å; V91-L132 WeakPolarHBondContact CA-O 3.43Å; V91-Y403 WeakPolarHBondContact O-CA 3.33Å; V91-I404 HydrophobicContact CG1-CG1 4.33Å; V91-I404 PolarHBondContact O-N 2.67Å
92R98.2Very high96.3Very high3 Ų342.7 Ų42.71%0.01122%0.223CC..EExtended strand (participates in β ladder)trans-124.4159.1175.6-59.2-17978.5164.70.2110.2Q131 L132 I133 I134 L396 Y401 P402 Y403R92-Q131 VanDerWaalsContact CD-OE1 3.32Å; R92-L132 PolarHBondContact N-O 2.86Å; R92-I133 HydrophobicContact CB-CG1 4.27Å; R92-I133 WeakPolarHBondContact O-CA 3.24Å; R92-I134 PolarHBondContact O-N 3.37Å; R92-L396 PolarHBondContact NH2-O 3.44Å; R92-Y401 PolarHBondContact NE-O 3.42Å; R92-Y401 PolarHBondContact NH2-O 2.66Å; R92-P402 VanDerWaalsContact CA-O 3.23Å; R92-P402 WeakPolarHBondContact CA-O 3.44Å; R92-Y403 VanDerWaalsContact CD-CE1 3.42Å; R92-Y403 VanDerWaalsContact CD-CZ 3.49Å; R92-Y403 HydrophobicContact CG-CD1 3.35Å; R92-Y403 HydrophobicContact CG-CD2 4.41Å; R92-Y403 HydrophobicContact CG-CE1 3.31Å; R92-Y403 HydrophobicContact CG-CE2 4.39Å; R92-Y403 HydrophobicContact CG-CG 3.93Å; R92-Y403 PolarHBondContact NH1-OH 3.3Å
93Y98.5Very high96.4Very high46 Ų4642.6 Ų42.618%0.1822%0.223CC..EExtended strand (participates in β ladder)trans-148.1152.5177.363.5-85.2000111.3G95 N100 A101 A104 I134 Y401 P402 I404Y93-G95 PolarHBondContact O-N 2.95Å; Y93-N100 HydrophobicContact CD2-CB 4.29Å; Y93-A101 HydrophobicContact CD2-CB 3.9Å; Y93-A101 HydrophobicContact CE1-CB 4.45Å; Y93-A101 HydrophobicContact CE2-CB 3.47Å; Y93-A101 VanDerWaalsContact CE2-CB 3.47Å; Y93-A104 HydrophobicContact CD1-CB 3.88Å; Y93-A104 HydrophobicContact CG-CB 4.14Å; Y93-I134 CarbonylContact C-O 3.51Å; Y93-I134 WeakPolarHBondContact CA-O 3.34Å; Y93-Y401 VanDerWaalsContact O-CA 3.28Å; Y93-Y401 WeakPolarHBondContact O-CA 3.31Å; Y93-P402 HydrophobicContact CD1-CG 4.32Å; Y93-P402 HydrophobicContact CD2-CG 4.25Å; Y93-P402 HydrophobicContact CE1-CB 4.3Å; Y93-P402 HydrophobicContact CE1-CG 3.74Å; Y93-P402 HydrophobicContact CE2-CG 3.66Å; Y93-P402 PolarHBondContact N-O 3.36Å; Y93-P402 VanDerWaalsContact O-CD 3.3Å; Y93-P402 WeakPolarHBondContact O-CD 3.46Å; Y93-I404 HydrophobicContact CD1-CD1 3.75Å; Y93-I404 HydrophobicContact CD1-CG1 3.97Å; Y93-I404 HydrophobicContact CE1-CD1 3.46Å; Y93-I404 VanDerWaalsContact CE1-CD1 3.46Å; Y93-I404 HydrophobicContact CE1-CG1 4.02Å
94R97.6Very high96.6Very high28 Ų2841.8 Ų41.811%0.10622%0.216CC..  trans-72.6117.5170.2-177.6-178.9167.7-14313.2110E96 N100 I134 L135 D136 F139 H400 Y401R94-E96 VanDerWaalsContact C-N 3.33Å; R94-E96 HydrophobicContact CG-CB 4.46Å; R94-E96 IonicContact CZ-OE2 2.9Å; R94-E96 VanDerWaalsContact CZ-OE2 3.24Å; R94-E96 IonicContact NE-OE2 2.73Å; R94-E96 PolarHBondContact NE-OE2 2.66Å; R94-E96 IonicContact NH2-OE2 2.66Å; R94-E96 PolarHBondContact NH2-OE2 2.79Å; R94-E96 PolarHBondContact O-N 3.42Å; R94-N100 PolarHBondContact O-ND2 2.78Å; R94-N100 VanDerWaalsContact O-ND2 3.09Å; R94-I134 PolarHBondContact N-O 3.4Å; R94-L135 HydrophobicContact CB-CD2 3.88Å; R94-D136 IonicContact CZ-OD1 2.91Å; R94-D136 IonicContact NH1-OD1 3.42Å; R94-D136 PolarHBondContact NH1-OD1 3.07Å; R94-D136 IonicContact NH1-OD2 2.72Å; R94-D136 PolarHBondContact NH1-OD2 2.97Å; R94-F139 VanDerWaalsContact CZ-CA 3.41Å; R94-H400 WeakPolarHBondContact CA-O 3.45Å; R94-Y401 HydrophobicContact CB-CD1 4.08Å; R94-Y401 HydrophobicContact CB-CE1 3.78Å; R94-Y401 HydrophobicContact CG-CE1 4Å
95G95.8Very high96.7Very high41 Ų4142.7 Ų42.742%0.42322%0.216SC..THydrogen-bonded Turntrans-74.5-13.8-171.500000115.9Y93 Y97 H400Y93-G95 PolarHBondContact O-N 2.95Å; G95-Y97 VanDerWaalsContact C-N 3.34Å; G95-H400 PolarHBondContact N-O 2.83Å
96E92.6Very high96.9Very high118 Ų11842.3 Ų42.355%0.55121%0.214SC*.THydrogen-bonded Turntrans-69.8-29.8-180-69.4-177.2161.900113R94R94-E96 VanDerWaalsContact C-N 3.33Å; R94-E96 HydrophobicContact CG-CB 4.46Å; R94-E96 IonicContact CZ-OE2 2.9Å; R94-E96 VanDerWaalsContact CZ-OE2 3.24Å; R94-E96 IonicContact NE-OE2 2.73Å; R94-E96 PolarHBondContact NE-OE2 2.66Å; R94-E96 IonicContact NH2-OE2 2.66Å; R94-E96 PolarHBondContact NH2-OE2 2.79Å; R94-E96 PolarHBondContact O-N 3.42Å
97Y94.4Very high97Very high35 Ų3537.2 Ų37.214%0.13719%0.192CC..SBendtrans-106.7114.1179.8-164.3-98.9000110.5Y59 G95 D99 N100 D136Y59-Y97 WeakPolarHBondContact CD1-OH 2.88Å; Y59-Y97 HydrophobicContact CE1-CE1 4.35Å; Y59-Y97 HydrophobicContact CE1-CE2 4.18Å; Y59-Y97 AromaticContact CE1-CZ 3.71Å; Y59-Y97 VanDerWaalsContact CE1-OH 3.28Å; Y59-Y97 WeakPolarHBondContact CE1-OH 3.29Å; G95-Y97 VanDerWaalsContact C-N 3.34Å; Y97-D99 VanDerWaalsContact C-N 3.3Å; Y97-D99 HydrophobicContact CD1-CB 4.05Å; Y97-D99 HydrophobicContact CE1-CB 3.74Å; Y97-D99 PolarHBondContact O-N 2.66Å; Y97-N100 WeakPolarHBondContact O-CB 3.34Å; Y97-N100 PolarHBondContact O-N 2.85Å; Y97-N100 VanDerWaalsContact O-N 3.12Å; Y97-D136 VanDerWaalsContact CB-OD1 3.28Å; Y97-D136 WeakPolarHBondContact CB-OD1 3.33Å; Y97-D136 HydrophobicContact CD1-CB 3.58Å; Y97-D136 HydrophobicContact CD2-CB 4.18Å; Y97-D136 HydrophobicContact CE1-CB 4.14Å; Y97-D136 HydrophobicContact CG-CB 3.61Å
98K93.6Very high97.2Very high169 Ų16937.4 Ų37.474%0.73519%0.193SC*.Hα-helixtrans-56-40.8-169.7-177.1-176.7173.9-170.70113.4N100 A101K98-N100 PolarHBondContact O-N 3.26Å; K98-A101 WeakPolarHBondContact O-CB 3.25Å; K98-A101 PolarHBondContact O-N 3.03Å
99D95.9Very high97.2Very high27 Ų2737.7 Ų37.714%0.14420%0.199CC..Hα-helixtrans-69.9-19.7-174.3-58-31.2000112.4F58 K67 M71 Y97 A101 T102 L103F58-D99 HydrophobicContact CE1-CB 4.41Å; K67-D99 VanDerWaalsContact CD-OD2 3.26Å; K67-D99 WeakPolarHBondContact CD-OD2 3.35Å; K67-D99 IonicContact NZ-OD2 2.72Å; K67-D99 PolarHBondContact NZ-OD2 2.9Å; M71-D99 HydrophobicContact SD-CB 4.19Å; Y97-D99 VanDerWaalsContact C-N 3.3Å; Y97-D99 HydrophobicContact CD1-CB 4.05Å; Y97-D99 HydrophobicContact CE1-CB 3.74Å; Y97-D99 PolarHBondContact O-N 2.66Å; D99-A101 VanDerWaalsContact C-N 3.28Å; D99-A101 PolarHBondContact O-N 3.4Å; D99-T102 PolarHBondContact O-N 2.87Å; D99-L103 PolarHBondContact O-N 3.17Å
100N98.2Very high97.1Very high0 Ų040.8 Ų40.80%021%0.213CC..Hα-helixtrans-62.7-37.6173.8-64.3-13.1000111.3Y93 R94 Y97 K98 A104 I134 D136 I444Y93-N100 HydrophobicContact CD2-CB 4.29Å; R94-N100 PolarHBondContact O-ND2 2.78Å; R94-N100 VanDerWaalsContact O-ND2 3.09Å; Y97-N100 WeakPolarHBondContact O-CB 3.34Å; Y97-N100 PolarHBondContact O-N 2.85Å; Y97-N100 VanDerWaalsContact O-N 3.12Å; K98-N100 PolarHBondContact O-N 3.26Å; N100-A104 WeakPolarHBondContact O-CB 3.41Å; N100-A104 PolarHBondContact O-N 3.49Å; N100-I134 HydrophobicContact CB-CG2 4.3Å; N100-D136 PolarHBondContact ND2-N 3.05Å; N100-D136 PolarHBondContact ND2-OD1 2.92Å; N100-I444 WeakPolarHBondContact OD1-CD1 3.39Å
101A97.7Very high97.1Very high29 Ų2939.3 Ų39.324%0.2420%0.2CC..Hα-helixtrans-66.1-42.8177.700000111.3Y93 K98 D99 A104 Q105Y93-A101 HydrophobicContact CD2-CB 3.9Å; Y93-A101 HydrophobicContact CE1-CB 4.45Å; Y93-A101 HydrophobicContact CE2-CB 3.47Å; Y93-A101 VanDerWaalsContact CE2-CB 3.47Å; K98-A101 WeakPolarHBondContact O-CB 3.25Å; K98-A101 PolarHBondContact O-N 3.03Å; D99-A101 VanDerWaalsContact C-N 3.28Å; D99-A101 PolarHBondContact O-N 3.4Å; A101-A104 PolarHBondContact O-N 3.43Å; A101-Q105 PolarHBondContact O-N 3.28Å
102T97.4Very high97Very high57 Ų5742.3 Ų42.335%0.3522%0.216SC..Hα-helixtrans-62.2-49.2177-51.40000110.9M71 D99 A104 Q105 L106M71-T102 HydrophobicContact CE-CG2 3.92Å; M71-T102 HydrophobicContact SD-CG2 4.04Å; D99-T102 PolarHBondContact O-N 2.87Å; T102-A104 VanDerWaalsContact C-N 3.33Å; T102-A104 PolarHBondContact O-N 2.86Å; T102-Q105 PolarHBondContact O-N 2.68Å; T102-L106 HydrophobicContact CG2-CD1 4.3Å; T102-L106 WeakPolarHBondContact O-CG 3.31Å; T102-L106 PolarHBondContact O-N 2.91Å
103L98.4Very high96.8Very high0 Ų044.8 Ų44.80%024%0.237CC..Hα-helixtrans-62.4-41.4177.7-179.561000111.5M71 L74 A75 D99 Q105 L106 V107 I134 F442 I444M71-L103 HydrophobicContact CB-CD1 4.42Å; M71-L103 VanDerWaalsContact O-CD1 3.31Å; M71-L103 WeakPolarHBondContact O-CD1 3.38Å; L74-L103 HydrophobicContact CB-CD1 4.08Å; A75-L103 HydrophobicContact CB-CD1 4Å; D99-L103 PolarHBondContact O-N 3.17Å; L103-Q105 VanDerWaalsContact C-N 3.34Å; L103-Q105 PolarHBondContact O-N 3.46Å; L103-L106 PolarHBondContact O-N 3.33Å; L103-V107 HydrophobicContact CD1-CG2 4.31Å; L103-V107 HydrophobicContact CG-CG2 4.43Å; L103-V107 VanDerWaalsContact O-CG2 3.29Å; L103-V107 WeakPolarHBondContact O-CG2 3.45Å; L103-V107 PolarHBondContact O-N 3.02Å; L103-I134 HydrophobicContact CB-CD1 4.48Å; L103-I134 HydrophobicContact CD2-CD1 4.27Å; L103-I134 HydrophobicContact CD2-CG2 3.93Å; L103-I134 HydrophobicContact CG-CD1 3.97Å; L103-I134 HydrophobicContact CG-CG2 4.47Å; L103-F442 HydrophobicContact CD2-CD1 4.06Å; L103-F442 HydrophobicContact CD2-CE1 3.81Å; L103-I444 HydrophobicContact CD2-CD1 3.68Å; L103-I444 HydrophobicContact CD2-CG1 3.86Å
104A98.5Very high96.7Very high0 Ų044.4 Ų44.40%024%0.236CC..Hα-helixtrans-63-38.9178.300000112.7V91 Y93 N100 A101 T102 V107 Q108 I134 I404V91-A104 HydrophobicContact CG1-CB 3.85Å; Y93-A104 HydrophobicContact CD1-CB 3.88Å; Y93-A104 HydrophobicContact CG-CB 4.14Å; N100-A104 WeakPolarHBondContact O-CB 3.41Å; N100-A104 PolarHBondContact O-N 3.49Å; A101-A104 PolarHBondContact O-N 3.43Å; T102-A104 VanDerWaalsContact C-N 3.33Å; T102-A104 PolarHBondContact O-N 2.86Å; A104-V107 PolarHBondContact O-N 3.44Å; A104-Q108 WeakPolarHBondContact O-CB 3.49Å; A104-Q108 PolarHBondContact O-N 3.42Å; A104-I134 HydrophobicContact CB-CD1 3.84Å; A104-I404 HydrophobicContact CB-CD1 3.73Å; A104-I404 HydrophobicContact CB-CG1 3.58Å
105Q98.3Very high96.5Very high82 Ų8245.7 Ų45.738%0.38324%0.242SC..Hα-helixtrans-64.9-46.7173.1-173.962.157.600111.5A101 T102 L103 V107 Q108 D109 I404A101-Q105 PolarHBondContact O-N 3.28Å; T102-Q105 PolarHBondContact O-N 2.68Å; L103-Q105 VanDerWaalsContact C-N 3.34Å; L103-Q105 PolarHBondContact O-N 3.46Å; Q105-V107 VanDerWaalsContact C-N 3.29Å; Q105-V107 PolarHBondContact O-N 3.23Å; Q105-Q108 WeakPolarHBondContact O-CB 3.36Å; Q105-Q108 PolarHBondContact O-N 3.34Å; Q105-Q108 VanDerWaalsContact O-N 3.11Å; Q105-D109 PolarHBondContact NE2-OD1 3.4Å; Q105-D109 VanDerWaalsContact O-CG 3.26Å; Q105-D109 PolarHBondContact O-N 3.32Å; Q105-I404 HydrophobicContact CB-CD1 4.39Å; Q105-I404 VanDerWaalsContact OE1-CG2 3.29Å
106L98.3Very high96.6Very high36 Ų3647.3 Ų47.319%0.18825%0.251CS..Hα-helixtrans-59.9-41177.9-69.3168.2000111.5M71 E72 A75 T102 L103 D109 K110M71-L106 HydrophobicContact CB-CD1 3.91Å; E72-L106 HydrophobicContact CG-CD1 4.16Å; E72-L106 HydrophobicContact CG-CD2 4.28Å; A75-L106 HydrophobicContact CB-CB 3.56Å; T102-L106 HydrophobicContact CG2-CD1 4.3Å; T102-L106 WeakPolarHBondContact O-CG 3.31Å; T102-L106 PolarHBondContact O-N 2.91Å; L103-L106 PolarHBondContact O-N 3.33Å; L106-D109 PolarHBondContact O-N 3.24Å; L106-K110 VanDerWaalsContact O-CG 3.3Å; L106-K110 WeakPolarHBondContact O-CG 3.37Å; L106-K110 PolarHBondContact O-N 2.88Å; L106-K110 VanDerWaalsContact O-N 3.13Å
107V98.4Very high96.6Very high0 Ų048.5 Ų48.50%026%0.261CS..Hα-helixtrans-61.8-46174.41710000110.6A75 L78 V91 L103 A104 Q105 D109 K110 L111 L132 I134A75-V107 HydrophobicContact CB-CG2 3.84Å; L78-V107 HydrophobicContact CB-CG2 4.14Å; L78-V107 HydrophobicContact CD1-CG2 3.73Å; V91-V107 HydrophobicContact CG2-CG1 4.39Å; L103-V107 HydrophobicContact CD1-CG2 4.31Å; L103-V107 HydrophobicContact CG-CG2 4.43Å; L103-V107 VanDerWaalsContact O-CG2 3.29Å; L103-V107 WeakPolarHBondContact O-CG2 3.45Å; L103-V107 PolarHBondContact O-N 3.02Å; A104-V107 PolarHBondContact O-N 3.44Å; Q105-V107 VanDerWaalsContact C-N 3.29Å; Q105-V107 PolarHBondContact O-N 3.23Å; V107-D109 VanDerWaalsContact C-N 3.34Å; V107-D109 PolarHBondContact O-N 3.05Å; V107-K110 PolarHBondContact O-N 2.81Å; V107-L111 HydrophobicContact CG1-CD1 3.85Å; V107-L111 HydrophobicContact CG1-CG 4.17Å; V107-L111 VanDerWaalsContact O-CG 3.29Å; V107-L111 WeakPolarHBondContact O-CG 3.44Å; V107-L111 PolarHBondContact O-N 3.12Å; V107-L132 HydrophobicContact CG1-CD2 3.71Å; V107-I134 HydrophobicContact CG2-CD1 4.09Å
108Q98.2Very high96.5Very high5 Ų549 Ų492%0.02327%0.267CS..Hα-helixtrans-57.6-46.4177.7-174.86566.600111.5Y88 A104 Q105 K110 L111 D112 I404Y88-Q108 PolarHBondContact OH-NE2 3.37Å; Y88-Q108 VanDerWaalsContact OH-NE2 3.08Å; A104-Q108 WeakPolarHBondContact O-CB 3.49Å; A104-Q108 PolarHBondContact O-N 3.42Å; Q105-Q108 WeakPolarHBondContact O-CB 3.36Å; Q105-Q108 PolarHBondContact O-N 3.34Å; Q105-Q108 VanDerWaalsContact O-N 3.11Å; Q108-K110 VanDerWaalsContact C-N 3.3Å; Q108-K110 PolarHBondContact O-N 2.82Å; Q108-L111 PolarHBondContact O-N 3.44Å; Q108-D112 PolarHBondContact NE2-OD1 3.29Å; Q108-D112 VanDerWaalsContact O-CG 3.23Å; Q108-D112 PolarHBondContact O-N 2.92Å; Q108-I404 HydrophobicContact CB-CG2 4.01Å; Q108-I404 HydrophobicContact CG-CG2 4.01Å
109D97.3Very high96.6Very high80 Ų8044.7 Ų44.743%0.42826%0.256SS..Hα-helixtrans-60.4-40.1179.3-61.7-14.3000111.6Q105 L106 V107 A113Q105-D109 PolarHBondContact NE2-OD1 3.4Å; Q105-D109 VanDerWaalsContact O-CG 3.26Å; Q105-D109 PolarHBondContact O-N 3.32Å; L106-D109 PolarHBondContact O-N 3.24Å; V107-D109 VanDerWaalsContact C-N 3.34Å; V107-D109 PolarHBondContact O-N 3.05Å; D109-A113 PolarHBondContact O-N 2.86Å
110K96.3Very high96.4Very high68 Ų6846.8 Ų46.830%0.29627%0.27SS..Hα-helixtrans-70.3-39.8176.6-61.6-66172.9167.60112.1A75 E76 A79 L106 V107 Q108 D112 A113 Y114A75-K110 HydrophobicContact CB-CG 4.5Å; E76-K110 HydrophobicContact CG-CD 3.83Å; E76-K110 HydrophobicContact CG-CG 4.25Å; E76-K110 IonicContact OE1-NZ 3.98Å; E76-K110 PolarHBondContact OE1-NZ 3.29Å; A79-K110 HydrophobicContact CB-CB 3.59Å; L106-K110 VanDerWaalsContact O-CG 3.3Å; L106-K110 WeakPolarHBondContact O-CG 3.37Å; L106-K110 PolarHBondContact O-N 2.88Å; L106-K110 VanDerWaalsContact O-N 3.13Å; V107-K110 PolarHBondContact O-N 2.81Å; Q108-K110 VanDerWaalsContact C-N 3.3Å; Q108-K110 PolarHBondContact O-N 2.82Å; K110-D112 VanDerWaalsContact C-N 3.31Å; K110-D112 PolarHBondContact O-N 2.8Å; K110-A113 PolarHBondContact O-N 3.44Å; K110-Y114 VanDerWaalsContact O-CD2 3.28Å; K110-Y114 WeakPolarHBondContact O-CD2 3.49Å; K110-Y114 PolarHBondContact O-N 3.01Å; K110-Y114 VanDerWaalsContact O-N 3.15Å
111L96.8Very high96.3Very high0 Ų047 Ų470%027%0.271CS..Hα-helixtrans-63.3-38.3175.2-70.1176000111.8A79 C82 Y88 P89 V91 V107 Q108 A113 Y114 K115A79-L111 HydrophobicContact CB-CD2 4.25Å; C82-L111 HydrophobicContact CB-CD2 3.39Å; Y88-L111 HydrophobicContact CD2-CB 4.04Å; Y88-L111 HydrophobicContact CE2-CB 3.87Å; P89-L111 HydrophobicContact CG-CD1 4.25Å; V91-L111 HydrophobicContact CG2-CD1 3.83Å; V107-L111 HydrophobicContact CG1-CD1 3.85Å; V107-L111 HydrophobicContact CG1-CG 4.17Å; V107-L111 VanDerWaalsContact O-CG 3.29Å; V107-L111 WeakPolarHBondContact O-CG 3.44Å; V107-L111 PolarHBondContact O-N 3.12Å; Q108-L111 PolarHBondContact O-N 3.44Å; L111-A113 VanDerWaalsContact C-N 3.32Å; L111-A113 PolarHBondContact O-N 3.23Å; L111-Y114 PolarHBondContact O-N 2.83Å; L111-K115 WeakPolarHBondContact O-CB 3.31Å; L111-K115 PolarHBondContact O-N 3.33Å
112D96.8Very high96Very high65 Ų6546.1 Ų46.135%0.34827%0.265SS..Hα-helixtrans-62.8-39.9177.4-70.6-6.7000111.4Y88 Q108 K110 K115 A116Y88-D112 WeakPolarHBondContact CE2-OD1 3.42Å; Y88-D112 PolarHBondContact OH-OD1 2.87Å; Q108-D112 PolarHBondContact NE2-OD1 3.29Å; Q108-D112 VanDerWaalsContact O-CG 3.23Å; Q108-D112 PolarHBondContact O-N 2.92Å; K110-D112 VanDerWaalsContact C-N 3.31Å; K110-D112 PolarHBondContact O-N 2.8Å; D112-K115 PolarHBondContact O-N 3.27Å; D112-A116 WeakPolarHBondContact O-CB 3.3Å; D112-A116 PolarHBondContact O-N 3.36Å
113A95Very high95.6Very high54 Ų5449.3 Ų49.345%0.44628%0.275SS..Hα-helixtrans-62-48.8173.500000111.8D109 K110 L111 K115 A116 D117D109-A113 PolarHBondContact O-N 2.86Å; K110-A113 PolarHBondContact O-N 3.44Å; L111-A113 VanDerWaalsContact C-N 3.32Å; L111-A113 PolarHBondContact O-N 3.23Å; A113-K115 VanDerWaalsContact C-N 3.32Å; A113-K115 PolarHBondContact O-N 3Å; A113-A116 WeakPolarHBondContact O-CB 3.46Å; A113-A116 PolarHBondContact O-N 3.45Å; A113-D117 PolarHBondContact O-N 2.88Å
114Y94.5Very high95.2Very high39 Ų3951.1 Ų51.115%0.15330%0.295CS..Hα-helixtrans-62.1-37.2176.9-84.1-68.2000113.2N36 A79 A83 K110 L111 D117 D118 M121N36-Y114 HydrophobicContact CB-CE1 4.38Å; N36-Y114 PolarHBondContact OD1-OH 2.87Å; A79-Y114 HydrophobicContact CB-CD2 3.87Å; A79-Y114 HydrophobicContact CB-CE2 3.71Å; A83-Y114 HydrophobicContact CB-CD1 3.77Å; A83-Y114 HydrophobicContact CB-CD2 4.36Å; A83-Y114 HydrophobicContact CB-CE1 3.93Å; A83-Y114 HydrophobicContact CB-CE2 4.49Å; A83-Y114 HydrophobicContact CB-CG 4.02Å; K110-Y114 VanDerWaalsContact O-CD2 3.28Å; K110-Y114 WeakPolarHBondContact O-CD2 3.49Å; K110-Y114 PolarHBondContact O-N 3.01Å; K110-Y114 VanDerWaalsContact O-N 3.15Å; L111-Y114 PolarHBondContact O-N 2.83Å; Y114-D117 PolarHBondContact O-N 3.32Å; Y114-D118 PolarHBondContact O-N 2.89Å; Y114-M121 HydrophobicContact CG-CE 4.4Å
115K95.2Very high94.6Very high54 Ų5456.5 Ų56.524%0.23533%0.329CS..Hα-helixtrans-70.7-30.9177-179.463175.1-179.60112.3Y88 L111 D112 A113 D117 D118 P119 M121Y88-K115 HydrophobicContact CD2-CB 3.79Å; Y88-K115 HydrophobicContact CD2-CD 4.39Å; Y88-K115 HydrophobicContact CD2-CG 4.09Å; Y88-K115 HydrophobicContact CE2-CB 3.79Å; Y88-K115 HydrophobicContact CE2-CG 4.11Å; Y88-K115 HydrophobicContact CG-CD 4.4Å; Y88-K115 HydrophobicContact CG-CG 4.48Å; L111-K115 WeakPolarHBondContact O-CB 3.31Å; L111-K115 PolarHBondContact O-N 3.33Å; D112-K115 PolarHBondContact O-N 3.27Å; A113-K115 VanDerWaalsContact C-N 3.32Å; A113-K115 PolarHBondContact O-N 3Å; K115-D117 VanDerWaalsContact C-N 3.35Å; K115-D118 CarbonylContact O-C 3.57Å; K115-D118 VanDerWaalsContact O-C 3.23Å; K115-P119 WeakPolarHBondContact CE-O 3.47Å; K115-P119 PolarHBondContact NZ-O 3.49Å; K115-P119 WeakPolarHBondContact O-CA 3.25Å; K115-M121 HydrophobicContact CD-CB 3.97Å; K115-M121 WeakPolarHBondContact CD-O 3.41Å; K115-M121 WeakPolarHBondContact CE-O 3.44Å; K115-M121 PolarHBondContact NZ-O 3.06Å
116A95.9Very high94.2Very high75 Ų7555 Ų5562%0.6232%0.324SS*.Hα-helixtrans-66.3-38.8173.100000111.5D112 A113D112-A116 WeakPolarHBondContact O-CB 3.3Å; D112-A116 PolarHBondContact O-N 3.36Å; A113-A116 WeakPolarHBondContact O-CB 3.46Å; A113-A116 PolarHBondContact O-N 3.45Å
117D93.1Very high93.9Very high143 Ų14355.7 Ų55.777%0.76533%0.326SS*.Hα-helixtrans-77.8-37.5178.1-70-18.9000113.1A113 Y114 K115A113-D117 PolarHBondContact O-N 2.88Å; Y114-D117 PolarHBondContact O-N 3.32Å; K115-D117 VanDerWaalsContact C-N 3.35Å
118D93.1Very high93.6Very high47 Ų4758.3 Ų58.325%0.25135%0.347SS..  trans-122.989.7172.1-175.62.7000111.4K86 Y114 K115 T120 M121K86-D118 IonicContact NZ-OD2 3.42Å; Y114-D118 PolarHBondContact O-N 2.89Å; K115-D118 CarbonylContact O-C 3.57Å; K115-D118 VanDerWaalsContact O-C 3.23Å; D118-T120 PolarHBondContact O-N 2.95Å; D118-T120 WeakPolarHBondContact OD1-CB 3.44Å; D118-T120 PolarHBondContact OD1-N 3.29Å; D118-T120 PolarHBondContact OD1-OG1 2.83Å; D118-T120 PolarHBondContact OD2-OG1 3.43Å; D118-M121 VanDerWaalsContact O-CB 3.28Å; D118-M121 WeakPolarHBondContact O-CB 3.47Å; D118-M121 PolarHBondContact O-N 3.09Å
119P94.8Very high93.4Very high78 Ų7861 Ų6151%0.50636%0.357SS..THydrogen-bonded Turntrans-60-14.3177-26.835.9000114.5K115 M121K115-P119 WeakPolarHBondContact CE-O 3.47Å; K115-P119 PolarHBondContact NZ-O 3.49Å; K115-P119 WeakPolarHBondContact O-CA 3.25Å; P119-M121 VanDerWaalsContact C-N 3.3Å
120T93.4Very high93.3Very high70 Ų7057.3 Ų57.343%0.42934%0.338SS..THydrogen-bonded Turntrans-81-9.8177.172.40000113.3D118 G122 E123D118-T120 PolarHBondContact O-N 2.95Å; D118-T120 WeakPolarHBondContact OD1-CB 3.44Å; D118-T120 PolarHBondContact OD1-N 3.29Å; D118-T120 PolarHBondContact OD1-OG1 2.83Å; D118-T120 PolarHBondContact OD2-OG1 3.43Å; T120-G122 PolarHBondContact O-N 3.4Å; T120-E123 WeakPolarHBondContact O-CB 3.4Å; T120-E123 PolarHBondContact O-N 3.48Å; T120-E123 VanDerWaalsContact O-N 3.09Å
121M94.2Very high93.4Very high4 Ų454.1 Ų54.12%0.0232%0.323CS..THydrogen-bonded Turntrans-60.9124.1-179.1-175.2178.8-66.900111.9A83 E87 Y114 K115 D118 P119 E123A83-M121 HydrophobicContact CB-CE 3.82Å; E87-M121 WeakPolarHBondContact O-CG 3.35Å; Y114-M121 HydrophobicContact CG-CE 4.4Å; K115-M121 HydrophobicContact CD-CB 3.97Å; K115-M121 WeakPolarHBondContact CD-O 3.41Å; K115-M121 WeakPolarHBondContact CE-O 3.44Å; K115-M121 PolarHBondContact NZ-O 3.06Å; D118-M121 VanDerWaalsContact O-CB 3.28Å; D118-M121 WeakPolarHBondContact O-CB 3.47Å; D118-M121 PolarHBondContact O-N 3.09Å; P119-M121 VanDerWaalsContact C-N 3.3Å; M121-E123 VanDerWaalsContact C-N 3.26Å; M121-E123 PolarHBondContact O-N 2.66Å
122G92.4Very high93.5Very high11 Ų1154.1 Ų54.111%0.11332%0.324CS..THydrogen-bonded Turntrans74.19.2-177.700000115.3K86 T120K86-G122 PolarHBondContact O-N 2.9Å; T120-G122 PolarHBondContact O-N 3.4Å
123E89.9Confident93.6Very high124 Ų12451 Ų5158%0.57931%0.307SS*.  trans-75.1146173.4-69.9-164.9161.600112.4T120 M121 K127T120-E123 WeakPolarHBondContact O-CB 3.4Å; T120-E123 PolarHBondContact O-N 3.48Å; T120-E123 VanDerWaalsContact O-N 3.09Å; M121-E123 VanDerWaalsContact C-N 3.26Å; M121-E123 PolarHBondContact O-N 2.66Å; E123-K127 WeakPolarHBondContact O-CD 3.38Å
124G88.6Confident93.8Very high39 Ų3948.5 Ų48.540%0.40229%0.286SS..SBendtrans114.3158178.100000113.3D126 A128G124-D126 PolarHBondContact O-N 2.91Å; G124-A128 VanDerWaalsContact O-CB 3.26Å; G124-A128 WeakPolarHBondContact O-CB 3.22Å; G124-A128 PolarHBondContact O-N 3.47Å
125P86.4Confident94Very high112 Ų11246.6 Ų46.673%0.72728%0.279SS*.THydrogen-bonded Turntrans-65.3-26.4-171.626.5-35.4000113.7
126D90.6Very high94.1Very high51 Ų5144.2 Ų44.227%0.27327%0.268SS..THydrogen-bonded Turntrans-87.2-50.2178.8-68.2-47.2000111.4G124 A128 R129 P437 K464G124-D126 PolarHBondContact O-N 2.91Å; D126-A128 VanDerWaalsContact C-N 3.32Å; D126-A128 PolarHBondContact O-N 3.08Å; D126-R129 WeakPolarHBondContact O-CB 3.49Å; D126-R129 PolarHBondContact O-N 3.32Å; D126-P437 HydrophobicContact CB-CG 4.21Å; D126-P437 WeakPolarHBondContact O-CA 3.32Å; D126-P437 WeakPolarHBondContact O-CB 3.31Å; D126-K464 WeakPolarHBondContact OD1-CE 3.32Å; D126-K464 IonicContact OD1-NZ 3.74Å
127K92.1Very high94.2Very high51 Ų5140.7 Ų40.722%0.22224%0.239CC..G310 helixtrans-63.3-32.5-179.3-65.6-176.9162.7-750114L85 K86 E87 E123 R129 S130L85-K127 PolarHBondContact O-NZ 3.18Å; K86-K127 PolarHBondContact O-NZ 3.03Å; E87-K127 IonicContact OE1-NZ 3.38Å; E87-K127 PolarHBondContact OE1-NZ 3.11Å; E123-K127 WeakPolarHBondContact O-CD 3.38Å; K127-R129 PolarHBondContact O-N 3.22Å; K127-R129 VanDerWaalsContact O-N 3.07Å; K127-S130 VanDerWaalsContact O-CB 3.31Å; K127-S130 WeakPolarHBondContact O-CB 3.35Å; K127-S130 PolarHBondContact O-N 3.48Å; K127-S130 PolarHBondContact O-OG 2.87Å
128A90.2Very high94.4Very high55 Ų5534.3 Ų34.346%0.45521%0.207SC..G310 helixtrans-63.8-13.6175.700000113.7G124 D126G124-A128 VanDerWaalsContact O-CB 3.26Å; G124-A128 WeakPolarHBondContact O-CB 3.22Å; G124-A128 PolarHBondContact O-N 3.47Å; D126-A128 VanDerWaalsContact C-N 3.32Å; D126-A128 PolarHBondContact O-N 3.08Å
129R94Very high94.5Very high62 Ų6232.6 Ų32.623%0.23420%0.197CC..G310 helixtrans-98.5-5.7177-63.417364.7-143.60.8112.7D126 K127 P437 W465D126-R129 WeakPolarHBondContact O-CB 3.49Å; D126-R129 PolarHBondContact O-N 3.32Å; K127-R129 PolarHBondContact O-N 3.22Å; K127-R129 VanDerWaalsContact O-N 3.07Å; R129-P437 HydrophobicContact CB-CB 3.91Å; R129-P437 HydrophobicContact CB-CG 4.11Å; R129-P437 VanDerWaalsContact NH1-CG 3.34Å; R129-W465 HydrophobicContact CB-CH2 4.24Å; R129-W465 HydrophobicContact CB-CZ2 4.46Å; R129-W465 WeakPolarHBondContact O-CH2 3.29Å
130S96.8Very high94.7Very high2 Ų229.1 Ų29.11%0.01417%0.174CC..  trans-61.5146-177.5-63.20000111.9E87 P89 A90 K127 R438E87-S130 WeakPolarHBondContact OE2-CB 3.47Å; E87-S130 PolarHBondContact OE2-OG 3.16Å; P89-S130 WeakPolarHBondContact CA-O 3.41Å; A90-S130 PolarHBondContact N-O 2.91Å; K127-S130 VanDerWaalsContact O-CB 3.31Å; K127-S130 WeakPolarHBondContact O-CB 3.35Å; K127-S130 PolarHBondContact O-N 3.48Å; K127-S130 PolarHBondContact O-OG 2.87Å; S130-R438 CarbonylContact C-O 3.53Å; S130-R438 WeakPolarHBondContact CA-O 3.42Å; S130-R438 WeakPolarHBondContact CB-O 3.41Å; S130-R438 PolarHBondContact OG-N 2.87Å; S130-R438 VanDerWaalsContact OG-N 3.13Å
131Q98.2Very high94.8Very high0 Ų026.9 Ų26.90%016%0.161CC..EExtended strand (participates in β ladder)trans-130.6147.2-179-68.1-179.980.600109.8A90 R92 A391 Y403 R438 L439 M440A90-Q131 WeakPolarHBondContact O-CA 3.47Å; R92-Q131 VanDerWaalsContact CD-OE1 3.32Å; Q131-A391 PolarHBondContact NE2-O 3.21Å; Q131-Y403 PolarHBondContact OE1-OH 3.42Å; Q131-R438 PolarHBondContact N-O 3.29Å; Q131-L439 HydrophobicContact CB-CD1 3.83Å; Q131-M440 PolarHBondContact O-N 3.04Å
132L98.7Very high95Very high1 Ų127.4 Ų27.41%0.00516%0.164CC..EExtended strand (participates in β ladder)trans-122.9121.5170.317162.1000108.2P89 A90 V91 R92 V107 M440P89-L132 HydrophobicContact CB-CB 3.94Å; P89-L132 HydrophobicContact CG-CB 3.68Å; P89-L132 HydrophobicContact CG-CD2 4.5Å; A90-L132 PolarHBondContact O-N 2.96Å; V91-L132 CarbonylContact C-O 3.59Å; V91-L132 WeakPolarHBondContact CA-O 3.43Å; R92-L132 PolarHBondContact N-O 2.86Å; V107-L132 HydrophobicContact CG1-CD2 3.71Å; L132-M440 CarbonylContact C-O 3.57Å; L132-M440 VanDerWaalsContact CA-O 3.29Å; L132-M440 WeakPolarHBondContact CA-O 3.38Å; L132-M440 HydrophobicContact CB-CB 4.37Å; L132-M440 HydrophobicContact CD1-CB 3.61Å
133I98.8Very high95.3Very high0 Ų027 Ų270%016%0.16CC..EExtended strand (participates in β ladder)trans-111.7123.7-179-53.8-178.6000109.8R92 L135 I387 A391 L396 Y401 L439 M440 V441 F442R92-I133 HydrophobicContact CB-CG1 4.27Å; R92-I133 WeakPolarHBondContact O-CA 3.24Å; I133-L135 HydrophobicContact CG2-CD2 3.83Å; I133-L135 HydrophobicContact CG2-CG 4.14Å; I133-I387 HydrophobicContact CD1-CG2 4.14Å; I133-A391 HydrophobicContact CD1-CB 3.68Å; I133-L396 HydrophobicContact CD1-CD2 3.75Å; I133-Y401 HydrophobicContact CG2-CD1 4.37Å; I133-L439 HydrophobicContact CD1-CD1 3.77Å; I133-L439 HydrophobicContact CG1-CD1 4.05Å; I133-M440 PolarHBondContact N-O 3.37Å; I133-V441 WeakPolarHBondContact O-CA 3.2Å; I133-F442 PolarHBondContact O-N 3.21Å
134I98.9Very high95.7Very high0 Ų021.2 Ų21.20%013%0.133CC..EExtended strand (participates in β ladder)trans-99.9128.2176-56.1-169.3000110.7R92 Y93 R94 N100 L103 A104 V107 F442 I444R92-I134 PolarHBondContact O-N 3.37Å; Y93-I134 CarbonylContact C-O 3.51Å; Y93-I134 WeakPolarHBondContact CA-O 3.34Å; R94-I134 PolarHBondContact N-O 3.4Å; N100-I134 HydrophobicContact CB-CG2 4.3Å; L103-I134 HydrophobicContact CB-CD1 4.48Å; L103-I134 HydrophobicContact CD2-CD1 4.27Å; L103-I134 HydrophobicContact CD2-CG2 3.93Å; L103-I134 HydrophobicContact CG-CD1 3.97Å; L103-I134 HydrophobicContact CG-CG2 4.47Å; A104-I134 HydrophobicContact CB-CD1 3.84Å; V107-I134 HydrophobicContact CG2-CD1 4.09Å; I134-F442 WeakPolarHBondContact CA-O 3.26Å; I134-F442 HydrophobicContact CG2-CD1 4.49Å; I134-I444 HydrophobicContact CG2-CD1 4.26Å
135L98.8Very high96.2Very high0 Ų019.4 Ų19.40%011%0.114CC..EExtended strand (participates in β ladder)trans-128.4148.6-177.5-55.4175.6000110.5R94 I133 F139 I384 I387 Y401 V441 F442 I443 I444R94-L135 HydrophobicContact CB-CD2 3.88Å; I133-L135 HydrophobicContact CG2-CD2 3.83Å; I133-L135 HydrophobicContact CG2-CG 4.14Å; L135-F139 HydrophobicContact CB-CD1 4.28Å; L135-F139 HydrophobicContact CB-CG 4.47Å; L135-F139 HydrophobicContact CD1-CD2 4.22Å; L135-F139 HydrophobicContact CD1-CE1 4.33Å; L135-F139 HydrophobicContact CD1-CE2 4.05Å; L135-F139 HydrophobicContact CD1-CG 4.46Å; L135-F139 HydrophobicContact CD1-CZ 4.1Å; L135-I384 HydrophobicContact CD1-CD1 3.42Å; L135-I384 VanDerWaalsContact CD1-CD1 3.42Å; L135-I387 HydrophobicContact CD1-CD1 4.36Å; L135-Y401 HydrophobicContact CD2-CD1 4.33Å; L135-Y401 HydrophobicContact CD2-CE1 3.7Å; L135-V441 HydrophobicContact CD1-CG1 3.9Å; L135-F442 PolarHBondContact N-O 2.73Å; L135-I443 HydrophobicContact CB-CG1 4.28Å; L135-I443 HydrophobicContact CD1-CG1 4.26Å; L135-I443 CarbonylContact O-C 3.23Å; L135-I443 WeakPolarHBondContact O-CA 3.23Å; L135-I444 PolarHBondContact O-N 3.34Å
136D98.2Very high96.8Very high3 Ų314.1 Ų14.12%0.0168%0.08CC..EExtended strand (participates in β ladder)trans-95.7149.9167.460.8-70.2000110.2R94 Y97 N100 G138 F139R94-D136 IonicContact CZ-OD1 2.91Å; R94-D136 IonicContact NH1-OD1 3.42Å; R94-D136 PolarHBondContact NH1-OD1 3.07Å; R94-D136 IonicContact NH1-OD2 2.72Å; R94-D136 PolarHBondContact NH1-OD2 2.97Å; Y97-D136 VanDerWaalsContact CB-OD1 3.28Å; Y97-D136 WeakPolarHBondContact CB-OD1 3.33Å; Y97-D136 HydrophobicContact CD1-CB 3.58Å; Y97-D136 HydrophobicContact CD2-CB 4.18Å; Y97-D136 HydrophobicContact CE1-CB 4.14Å; Y97-D136 HydrophobicContact CG-CB 3.61Å; N100-D136 PolarHBondContact ND2-N 3.05Å; N100-D136 PolarHBondContact ND2-OD1 2.92Å; D136-G138 PolarHBondContact O-N 3.35Å; D136-G138 PolarHBondContact OD2-N 3.48Å; D136-F139 WeakPolarHBondContact O-CB 3.26Å; D136-F139 WeakPolarHBondContact O-CD1 3.12Å; D136-F139 PolarHBondContact O-N 3.08Å
137R97.6Very high97.2Very high2 Ų212 Ų121%0.0087%0.068CC..G310 helixtrans-55.4-28.2-177-167.858.1-86.8175-8114.8Y59 F139 D140 L348 I444 G446 E451Y59-R137 HydrophobicContact CE2-CB 4.21Å; Y59-R137 PolarHBondContact OH-N 2.9Å; R137-F139 PolarHBondContact O-N 3.39Å; R137-F139 VanDerWaalsContact O-N 3.11Å; R137-D140 PolarHBondContact NH2-O 3.08Å; R137-L348 HydrophobicContact CB-CD2 3.9Å; R137-L348 HydrophobicContact CB-CG 4.48Å; R137-L348 HydrophobicContact CG-CD2 3.71Å; R137-I444 WeakPolarHBondContact CB-O 3.37Å; R137-I444 PolarHBondContact N-O 3.34Å; R137-I444 VanDerWaalsContact N-O 3.09Å; R137-G446 VanDerWaalsContact CD-O 3.3Å; R137-G446 WeakPolarHBondContact CD-O 3.28Å; R137-G446 PolarHBondContact NH1-O 2.98Å; R137-E451 IonicContact CZ-OE1 3.53Å; R137-E451 IonicContact CZ-OE2 2.84Å; R137-E451 IonicContact NH1-OE1 3.13Å; R137-E451 PolarHBondContact NH1-OE1 3.49Å; R137-E451 IonicContact NH1-OE2 2.71Å; R137-E451 PolarHBondContact NH1-OE2 3.48Å; R137-E451 IonicContact NH2-OE1 2.78Å; R137-E451 PolarHBondContact NH2-OE1 3.29Å; R137-E451 IonicContact NH2-OE2 3.8Å
138G96.3Very high97.4Very high9 Ų910.3 Ų10.39%0.0936%0.061CC..G310 helixtrans-66.9-4.3177.700000115D136 D140 L348D136-G138 PolarHBondContact O-N 3.35Å; D136-G138 PolarHBondContact OD2-N 3.48Å; G138-D140 VanDerWaalsContact C-N 3.33Å; G138-L348 WeakPolarHBondContact CA-O 3.48Å
139F96.6Very high97.8Very high11 Ų117.9 Ų7.95%0.0484%0.04CC..G310 helixtrans-66.3-34.9178.689.1-76.8000113.7R94 L135 D136 R137 L383 I384 I387 I443 E451R94-F139 VanDerWaalsContact CZ-CA 3.41Å; L135-F139 HydrophobicContact CB-CD1 4.28Å; L135-F139 HydrophobicContact CB-CG 4.47Å; L135-F139 HydrophobicContact CD1-CD2 4.22Å; L135-F139 HydrophobicContact CD1-CE1 4.33Å; L135-F139 HydrophobicContact CD1-CE2 4.05Å; L135-F139 HydrophobicContact CD1-CG 4.46Å; L135-F139 HydrophobicContact CD1-CZ 4.1Å; D136-F139 WeakPolarHBondContact O-CB 3.26Å; D136-F139 WeakPolarHBondContact O-CD1 3.12Å; D136-F139 PolarHBondContact O-N 3.08Å; R137-F139 PolarHBondContact O-N 3.39Å; R137-F139 VanDerWaalsContact O-N 3.11Å; F139-L383 HydrophobicContact CD2-CD2 4.17Å; F139-L383 HydrophobicContact CE2-CB 4.43Å; F139-L383 WeakPolarHBondContact O-CD2 3.45Å; F139-I384 HydrophobicContact CE2-CB 4.07Å; F139-I384 HydrophobicContact CE2-CD1 4.33Å; F139-I384 HydrophobicContact CZ-CB 4.09Å; F139-I384 HydrophobicContact CZ-CD1 4.44Å; F139-I387 HydrophobicContact CD2-CD1 3.85Å; F139-I387 HydrophobicContact CE2-CD1 3.97Å; F139-I443 HydrophobicContact CE1-CD1 3.88Å; F139-I443 HydrophobicContact CE1-CG1 4.14Å; F139-I443 HydrophobicContact CE1-CG2 4.07Å; F139-I443 HydrophobicContact CZ-CD1 4.03Å; F139-E451 VanDerWaalsContact CZ-OE1 3.23Å; F139-E451 WeakPolarHBondContact CZ-OE1 3.3Å
140D97.4Very high98Very high4 Ų45.6 Ų5.62%0.0213%0.033CC..  trans-144.493.2177.2-175.5-6.9000108R137 G138 V142 S143 P144 L383R137-D140 PolarHBondContact NH2-O 3.08Å; G138-D140 VanDerWaalsContact C-N 3.33Å; D140-V142 VanDerWaalsContact C-N 3.29Å; D140-V142 WeakPolarHBondContact OD1-CB 3.47Å; D140-V142 PolarHBondContact OD1-N 3.02Å; D140-S143 VanDerWaalsContact CG-OG 3.26Å; D140-S143 PolarHBondContact OD1-N 3.31Å; D140-S143 PolarHBondContact OD1-OG 3.27Å; D140-S143 WeakPolarHBondContact OD2-CB 3.42Å; D140-S143 PolarHBondContact OD2-OG 3.14Å; D140-P144 WeakPolarHBondContact O-CD 3.42Å; D140-P144 WeakPolarHBondContact O-CG 3.35Å; D140-L383 HydrophobicContact CB-CB 4.03Å; D140-L383 WeakPolarHBondContact OD2-CB 3.31Å; D140-L383 PolarHBondContact OD2-N 2.67Å
141P97.1Very high98.1Very high23 Ų235.5 Ų5.515%0.1493%0.033CC..SBendtrans-83.4-7.2175.735.1-36.4000112.5F315 V350P141-F315 HydrophobicContact CB-CD1 4.49Å; P141-F315 HydrophobicContact CB-CD2 4.32Å; P141-F315 HydrophobicContact CB-CE1 4.04Å; P141-F315 HydrophobicContact CB-CE2 3.83Å; P141-F315 HydrophobicContact CB-CZ 3.67Å; P141-F315 HydrophobicContact CG-CD1 4.18Å; P141-F315 HydrophobicContact CG-CD2 4.22Å; P141-F315 HydrophobicContact CG-CE1 4.21Å; P141-F315 HydrophobicContact CG-CE2 4.23Å; P141-F315 HydrophobicContact CG-CG 4.21Å; P141-F315 HydrophobicContact CG-CZ 4.22Å; P141-F315 WeakPolarHBondContact O-CE2 3.29Å; P141-V350 HydrophobicContact CB-CG1 4.18Å; P141-V350 HydrophobicContact CB-CG2 3.87Å; P141-V350 HydrophobicContact CG-CG1 3.95Å; P141-V350 HydrophobicContact CG-CG2 4.09Å
142V98.2Very high98.2Very high15 Ų155.6 Ų5.69%0.0913%0.033CC..SBendtrans-82.4-52.8-177.1173.70000110.5D140 P144 V145 L146 A275 L312 F315 W380D140-V142 VanDerWaalsContact C-N 3.29Å; D140-V142 WeakPolarHBondContact OD1-CB 3.47Å; D140-V142 PolarHBondContact OD1-N 3.02Å; V142-P144 VanDerWaalsContact C-CD 3.42Å; V142-P144 VanDerWaalsContact C-N 3.32Å; V142-V145 WeakPolarHBondContact O-CG2 3.34Å; V142-V145 PolarHBondContact O-N 3.05Å; V142-V145 VanDerWaalsContact O-N 3.12Å; V142-L146 HydrophobicContact CG1-CD1 3.69Å; V142-L146 HydrophobicContact CG1-CG 4.1Å; V142-L146 PolarHBondContact O-N 3.44Å; V142-A275 HydrophobicContact CG1-CB 3.76Å; V142-L312 HydrophobicContact CB-CD2 4.41Å; V142-L312 HydrophobicContact CG1-CD2 3.77Å; V142-L312 HydrophobicContact CG2-CD2 4.49Å; V142-F315 HydrophobicContact CG2-CB 4.1Å; V142-F315 HydrophobicContact CG2-CD2 3.83Å; V142-F315 HydrophobicContact CG2-CG 4.34Å; V142-W380 HydrophobicContact CB-CH2 3.82Å; V142-W380 HydrophobicContact CB-CZ2 3.62Å; V142-W380 HydrophobicContact CG1-CD2 3.94Å; V142-W380 HydrophobicContact CG1-CE3 4.13Å; V142-W380 HydrophobicContact CG1-CH2 3.69Å; V142-W380 HydrophobicContact CG1-CZ2 3.51Å; V142-W380 HydrophobicContact CG1-CZ3 3.99Å; V142-W380 HydrophobicContact CG2-CH2 4.15Å; V142-W380 HydrophobicContact CG2-CZ2 4.43Å
143S98.4Very high98.1Very high3 Ų36 Ų62%0.0214%0.036CC..G310 helixtrans-54.7-38.5-177-60.80000114.7D140 V145 W380 P382D140-S143 VanDerWaalsContact CG-OG 3.26Å; D140-S143 PolarHBondContact OD1-N 3.31Å; D140-S143 PolarHBondContact OD1-OG 3.27Å; D140-S143 WeakPolarHBondContact OD2-CB 3.42Å; D140-S143 PolarHBondContact OD2-OG 3.14Å; S143-V145 VanDerWaalsContact C-N 3.29Å; S143-V145 PolarHBondContact O-N 3.12Å; S143-W380 PolarHBondContact OG-NE1 3.12Å; S143-P382 VanDerWaalsContact OG-CA 3.25Å; S143-P382 WeakPolarHBondContact OG-CA 3.34Å; S143-P382 WeakPolarHBondContact OG-CB 3.26Å
144P98.4Very high98.1Very high3 Ų36 Ų62%0.0194%0.037CC..G310 helixtrans-66.9-20178.5-30.341.6000116.6D140 V142 F475 P477 L480D140-P144 WeakPolarHBondContact O-CD 3.42Å; D140-P144 WeakPolarHBondContact O-CG 3.35Å; V142-P144 VanDerWaalsContact C-CD 3.42Å; V142-P144 VanDerWaalsContact C-N 3.32Å; P144-F475 HydrophobicContact CB-CE2 3.59Å; P144-F475 HydrophobicContact CB-CZ 3.62Å; P144-F475 HydrophobicContact CG-CE2 4.29Å; P144-F475 HydrophobicContact CG-CZ 3.88Å; P144-P477 WeakPolarHBondContact O-CA 3.25Å; P144-P477 WeakPolarHBondContact O-CG 3.4Å; P144-L480 HydrophobicContact CB-CD2 3.44Å; P144-L480 VanDerWaalsContact CB-CD2 3.44Å; P144-L480 HydrophobicContact CG-CD2 4.47Å
145V98.6Very high98.1Very high0 Ų06 Ų60%04%0.037CC..G310 helixtrans-112.2-4.4-172.4-590000113.5V142 S143 R308 L311 L312 F315 L480V142-V145 WeakPolarHBondContact O-CG2 3.34Å; V142-V145 PolarHBondContact O-N 3.05Å; V142-V145 VanDerWaalsContact O-N 3.12Å; S143-V145 VanDerWaalsContact C-N 3.29Å; S143-V145 PolarHBondContact O-N 3.12Å; V145-R308 HydrophobicContact CB-CG 4.32Å; V145-R308 PolarHBondContact O-NE 3.28Å; V145-R308 PolarHBondContact O-NH2 3.05Å; V145-L311 HydrophobicContact CG1-CD1 4.32Å; V145-L312 HydrophobicContact CG2-CD2 3.81Å; V145-L312 HydrophobicContact CG2-CG 3.97Å; V145-F315 HydrophobicContact CG2-CE2 4.09Å; V145-L480 HydrophobicContact CG1-CD2 4.05Å
146L98.5Very high98.1Very high2 Ų26.8 Ų6.81%0.014%0.04CC..SBendtrans-77.6143.3178.1-77.3172.9000111.9V142 E148 E271 A275 R308 L312 W380V142-L146 HydrophobicContact CG1-CD1 3.69Å; V142-L146 HydrophobicContact CG1-CG 4.1Å; V142-L146 PolarHBondContact O-N 3.44Å; L146-E148 PolarHBondContact O-N 3.43Å; L146-E271 HydrophobicContact CD2-CB 3.72Å; L146-E271 HydrophobicContact CD2-CG 4.42Å; L146-A275 HydrophobicContact CD1-CB 4.1Å; L146-A275 HydrophobicContact CD2-CB 4.09Å; L146-R308 PolarHBondContact O-NH2 3.49Å; L146-R308 VanDerWaalsContact O-NH2 3.14Å; L146-L312 HydrophobicContact CD2-CD1 3.76Å; L146-L312 HydrophobicContact CD2-CD2 3.96Å; L146-L312 HydrophobicContact CG-CD2 4.26Å; L146-W380 HydrophobicContact CD1-CB 3.74Å; L146-W380 HydrophobicContact CD1-CD2 3.97Å; L146-W380 HydrophobicContact CD1-CG 3.36Å
147H98.8Very high98.1Very high5 Ų57.7 Ų7.72%0.0235%0.045CC..PPolyproline II helixtrans-71.7116.4163.6-75.194.9000109D157 V264 E271 D305 R308H147-D157 IonicContact CD2-OD2 3.24Å; H147-D157 PolarHBondContact CD2-OD2 3.13Å; H147-D157 IonicContact CG-OD2 2.66Å; H147-D157 IonicContact NE2-OD2 3.17Å; H147-V264 HydrophobicContact CB-CG1 4.44Å; H147-E271 WeakPolarHBondContact CB-OE2 3.48Å; H147-E271 IonicContact CE1-OE1 3.6Å; H147-E271 IonicContact CG-OE1 3.32Å; H147-E271 IonicContact CG-OE2 2.72Å; H147-E271 PolarHBondContact N-OE2 2.98Å; H147-E271 IonicContact ND1-OE1 2.81Å; H147-E271 PolarHBondContact ND1-OE1 3.46Å; H147-E271 IonicContact ND1-OE2 3.25Å; H147-E271 PolarHBondContact ND1-OE2 2.72Å; H147-D305 IonicContact CE1-OD1 3.72Å; H147-D305 PolarHBondContact CE1-OD1 3.05Å; H147-D305 VanDerWaalsContact CE1-OD1 3.26Å; H147-D305 IonicContact NE2-OD1 3.98Å; H147-R308 PolarHBondContact CD2-NH2 3.48Å; H147-R308 PolarHBondContact CE1-NH1 3Å; H147-R308 VanDerWaalsContact CG-NH2 3.29Å; H147-R308 VanDerWaalsContact N-NH2 3.13Å; H147-R308 PolarHBondContact ND1-NH2 2.97Å; H147-R308 PolarHBondContact NE2-NH1 2.85Å
148E98.1Very high98.1Very high16 Ų168.8 Ų8.88%0.0755%0.051CC..PPolyproline II helixtrans-99.4142.7179.9-80.3-82.9174.800110.9L146 A153 M154 S450 R453L146-E148 PolarHBondContact O-N 3.43Å; E148-A153 HydrophobicContact CB-CB 3.57Å; E148-A153 HydrophobicContact CG-CB 4.36Å; E148-M154 WeakPolarHBondContact O-CA 3.41Å; E148-M154 WeakPolarHBondContact O-CB 3.29Å; E148-S450 VanDerWaalsContact CD-CB 3.41Å; E148-S450 WeakPolarHBondContact OE1-CB 3.43Å; E148-R453 IonicContact OE1-NH2 3.21Å; E148-R453 IonicContact OE2-CZ 2.78Å; E148-R453 IonicContact OE2-NH1 3.15Å; E148-R453 PolarHBondContact OE2-NH1 3.2Å; E148-R453 IonicContact OE2-NH2 2.66Å
149L98.3Very high98.2Very high4 Ų49 Ų92%0.0215%0.05CC..  trans-110.914.5-174.3-56.9-178000113.2M154 I198 Y260 L377L149-M154 HydrophobicContact CD2-CE 4.14Å; L149-M154 HydrophobicContact CD2-SD 4.17Å; L149-I198 HydrophobicContact CB-CG2 4.25Å; L149-I198 PolarHBondContact O-N 3.35Å; L149-Y260 HydrophobicContact CD1-CE2 4.13Å; L149-Y260 HydrophobicContact CD2-CD2 3.81Å; L149-Y260 HydrophobicContact CD2-CE2 3.69Å; L149-L377 HydrophobicContact CD1-CB 3.81Å
150T98.4Very high98.2Very high14 Ų1413.4 Ų13.49%0.0868%0.079CC..BIsolated β-bridgetrans-88.3143.6166.757.80000110.7Q152 A153 M154 K196 R453T150-Q152 PolarHBondContact O-N 3.23Å; T150-A153 PolarHBondContact O-N 3.44Å; T150-A153 VanDerWaalsContact O-N 3.12Å; T150-M154 WeakPolarHBondContact O-CB 3.5Å; T150-M154 PolarHBondContact O-N 3.18Å; T150-K196 CarbonylContact C-O 3.45Å; T150-K196 VanDerWaalsContact CA-O 3.29Å; T150-K196 WeakPolarHBondContact CA-O 3.31Å; T150-R453 PolarHBondContact OG1-NH1 3.23Å
151F98.6Very high98.2Very high0 Ų014.1 Ų14.10%08%0.083CC..Hα-helixtrans-51-50.1-159.9-166.6-147.3000115.4G155 W190 L193 R194 K196 I198 V201 H249 L252 A253F151-G155 PolarHBondContact O-N 3.29Å; F151-W190 HydrophobicContact CD1-CE3 4.28Å; F151-W190 AromaticContact CD1-CZ3 3.97Å; F151-W190 HydrophobicContact CD1-CZ3 3.97Å; F151-W190 HydrophobicContact CE1-CE3 4.17Å; F151-W190 HydrophobicContact CE1-CZ3 4.02Å; F151-L193 WeakPolarHBondContact CB-O 3.49Å; F151-L193 HydrophobicContact CD1-CB 3.7Å; F151-L193 HydrophobicContact CE1-CB 4.03Å; F151-L193 HydrophobicContact CE1-CD1 4.21Å; F151-R194 PolarHBondContact N-O 2.99Å; F151-K196 PolarHBondContact N-O 3.02Å; F151-I198 HydrophobicContact CD2-CD1 3.97Å; F151-I198 HydrophobicContact CE2-CD1 4.35Å; F151-V201 HydrophobicContact CB-CG2 3.8Å; F151-V201 HydrophobicContact CD1-CG1 4.04Å; F151-V201 HydrophobicContact CD1-CG2 4.3Å; F151-V201 HydrophobicContact CD2-CG1 4.02Å; F151-V201 HydrophobicContact CD2-CG2 4.16Å; F151-V201 HydrophobicContact CE1-CG1 3.92Å; F151-V201 HydrophobicContact CE2-CG1 3.91Å; F151-V201 HydrophobicContact CG-CG1 4.08Å; F151-V201 HydrophobicContact CG-CG2 3.85Å; F151-V201 HydrophobicContact CZ-CG1 3.84Å; F151-H249 AromaticContact CE1-ND1 3.72Å; F151-H249 HydrophobicContact CZ-CB 4.47Å; F151-L252 HydrophobicContact CE1-CD2 4.1Å; F151-L252 HydrophobicContact CE2-CB 4.23Å; F151-L252 HydrophobicContact CE2-CD2 3.96Å; F151-L252 HydrophobicContact CE2-CG 3.73Å; F151-L252 HydrophobicContact CZ-CB 3.95Å; F151-L252 HydrophobicContact CZ-CD2 3.55Å; F151-L252 HydrophobicContact CZ-CG 3.7Å; F151-A253 HydrophobicContact CE2-CB 4.01Å; F151-A253 HydrophobicContact CZ-CB 4.4Å
152Q98.7Very high98.1Very high3 Ų319.5 Ų19.51%0.01411%0.106CC..Hα-helixtrans-67.7-51.6178.9173.1-177.238.200112.2E43 T150 M154 G155 Y156 W190 R194 H195 F449E43-Q152 PolarHBondContact OE1-NE2 3.04Å; T150-Q152 PolarHBondContact O-N 3.23Å; Q152-M154 VanDerWaalsContact C-N 3.28Å; Q152-M154 PolarHBondContact O-N 2.95Å; Q152-G155 PolarHBondContact O-N 3.45Å; Q152-Y156 HydrophobicContact CG-CD2 4.11Å; Q152-Y156 HydrophobicContact CG-CE2 4.11Å; Q152-Y156 VanDerWaalsContact O-CD2 3.24Å; Q152-Y156 WeakPolarHBondContact O-CD2 3.39Å; Q152-Y156 PolarHBondContact O-N 3.32Å; Q152-W190 HydrophobicContact CB-CH2 3.69Å; Q152-W190 HydrophobicContact CB-CZ2 3.82Å; Q152-W190 HydrophobicContact CG-CH2 3.97Å; Q152-W190 HydrophobicContact CG-CZ2 3.72Å; Q152-R194 HydrophobicContact CB-CB 3.84Å; Q152-R194 VanDerWaalsContact CB-O 3.3Å; Q152-R194 WeakPolarHBondContact CB-O 3.14Å; Q152-R194 PolarHBondContact N-O 3.12Å; Q152-H195 PolarHBondContact OE1-CE1 2.76Å; Q152-F449 VanDerWaalsContact CD-CD1 3.47Å; Q152-F449 HydrophobicContact CG-CD1 3.5Å; Q152-F449 VanDerWaalsContact CG-CD1 3.5Å; Q152-F449 HydrophobicContact CG-CE1 3.85Å; Q152-F449 HydrophobicContact CG-CG 4.2Å
153A98.6Very high97.9Very high8 Ų825.7 Ų25.77%0.06614%0.139CC..Hα-helixtrans-58.5-43-179.500000111.8E148 T150 D157 F449E148-A153 HydrophobicContact CB-CB 3.57Å; E148-A153 HydrophobicContact CG-CB 4.36Å; T150-A153 PolarHBondContact O-N 3.44Å; T150-A153 VanDerWaalsContact O-N 3.12Å; A153-D157 WeakPolarHBondContact O-CB 3.3Å; A153-D157 PolarHBondContact O-N 2.93Å; A153-D157 VanDerWaalsContact O-N 3.12Å; A153-F449 HydrophobicContact CB-CB 3.61Å
154M98.6Very high97.8Very high1 Ų127.3 Ų27.31%0.00515%0.147CC..Hα-helixtrans-66-45.3177.9-169.9179-177.400112.3E148 L149 T150 Q152 D157 L158 I198 C256 Y260E148-M154 WeakPolarHBondContact O-CA 3.41Å; E148-M154 WeakPolarHBondContact O-CB 3.29Å; L149-M154 HydrophobicContact CD2-CE 4.14Å; L149-M154 HydrophobicContact CD2-SD 4.17Å; T150-M154 WeakPolarHBondContact O-CB 3.5Å; T150-M154 PolarHBondContact O-N 3.18Å; Q152-M154 VanDerWaalsContact C-N 3.28Å; Q152-M154 PolarHBondContact O-N 2.95Å; M154-D157 PolarHBondContact O-N 3.37Å; M154-L158 HydrophobicContact CE-CD1 3.65Å; M154-L158 HydrophobicContact CG-CD1 3.78Å; M154-L158 HydrophobicContact CG-CG 4.36Å; M154-L158 WeakPolarHBondContact O-CB 3.4Å; M154-L158 WeakPolarHBondContact O-CG 3.27Å; M154-L158 PolarHBondContact O-N 3.04Å; M154-I198 HydrophobicContact CE-CG1 4.37Å; M154-I198 HydrophobicContact CE-CG2 4.43Å; M154-I198 HydrophobicContact SD-CB 3.66Å; M154-I198 HydrophobicContact SD-CD1 4.22Å; M154-I198 HydrophobicContact SD-CG1 3.69Å; M154-I198 HydrophobicContact SD-CG2 3.76Å; M154-C256 HydrophobicContact CE-CB 3.98Å; M154-C256 WeakPolarHBondContact CE-O 3.41Å; M154-C256 HydrophobicContact CG-CB 4.37Å; M154-C256 HydrophobicContact SD-CB 4Å; M154-Y260 HydrophobicContact CE-CD2 3.95Å; M154-Y260 HydrophobicContact CE-CG 3.96Å
155G98.4Very high97.8Very high1 Ų129 Ų291%0.0116%0.157CC..Hα-helixtrans-62.1-44.1-179.500000112.1F151 Q152 L159 I161F151-G155 PolarHBondContact O-N 3.29Å; Q152-G155 PolarHBondContact O-N 3.45Å; G155-L159 WeakPolarHBondContact O-CB 3.36Å; G155-L159 PolarHBondContact O-N 2.99Å; G155-I161 WeakPolarHBondContact O-CD1 3.35Å
156Y98.6Very high97.7Very high16 Ų1629.1 Ų29.16%0.06316%0.158CC..Hα-helixtrans-74.8-25.2179.9-80-108.2000113.4Q152 I161 D164 L183 W190 F449 T476Q152-Y156 HydrophobicContact CG-CD2 4.11Å; Q152-Y156 HydrophobicContact CG-CE2 4.11Å; Q152-Y156 VanDerWaalsContact O-CD2 3.24Å; Q152-Y156 WeakPolarHBondContact O-CD2 3.39Å; Q152-Y156 PolarHBondContact O-N 3.32Å; Y156-I161 HydrophobicContact CD1-CB 4.29Å; Y156-I161 HydrophobicContact CD1-CG2 4.03Å; Y156-I161 HydrophobicContact CD2-CD1 3.99Å; Y156-I161 HydrophobicContact CE1-CB 4.41Å; Y156-I161 HydrophobicContact CE1-CG2 3.64Å; Y156-I161 HydrophobicContact CE2-CD1 4.2Å; Y156-I161 HydrophobicContact CE2-CG2 4.24Å; Y156-I161 HydrophobicContact CG-CD1 4.38Å; Y156-I161 HydrophobicContact CG-CG2 4.49Å; Y156-D164 WeakPolarHBondContact OH-CA 3.49Å; Y156-D164 WeakPolarHBondContact OH-CB 3.48Å; Y156-D164 PolarHBondContact OH-OD1 3.4Å; Y156-L183 HydrophobicContact CE2-CD1 4.02Å; Y156-W190 HydrophobicContact CE2-CH2 4.06Å; Y156-W190 HydrophobicContact CE2-CZ2 4.05Å; Y156-F449 HydrophobicContact CD1-CE1 4.33Å; Y156-F449 AromaticContact CD1-CE2 3.69Å; Y156-F449 HydrophobicContact CD1-CE2 3.69Å; Y156-F449 AromaticContact CD1-CZ 3.38Å; Y156-F449 HydrophobicContact CD1-CZ 3.38Å; Y156-F449 HydrophobicContact CD2-CE1 4.43Å; Y156-F449 HydrophobicContact CD2-CE2 4.46Å; Y156-F449 HydrophobicContact CD2-CZ 4.12Å; Y156-F449 HydrophobicContact CE1-CE1 4.42Å; Y156-F449 HydrophobicContact CE1-CE2 4.49Å; Y156-F449 AromaticContact CE1-CZ 3.73Å; Y156-F449 HydrophobicContact CE1-CZ 3.73Å; Y156-F449 HydrophobicContact CE2-CZ 4.43Å; Y156-F449 HydrophobicContact CG-CD2 4.43Å; Y156-F449 HydrophobicContact CG-CE1 4.31Å; Y156-F449 AromaticContact CG-CE2 3.66Å; Y156-F449 HydrophobicContact CG-CE2 3.66Å; Y156-F449 AromaticContact CG-CZ 3.58Å; Y156-F449 HydrophobicContact CG-CZ 3.58Å; Y156-T476 VanDerWaalsContact O-CG2 3.31Å; Y156-T476 WeakPolarHBondContact O-CG2 3.27Å
157D98.4Very high97.6Very high21 Ų2134 Ų3411%0.11218%0.179CC..Hα-helixtrans-77.9-45.8174.8-17219.8000111.6H147 A153 M154 R308 P477H147-D157 IonicContact CD2-OD2 3.24Å; H147-D157 PolarHBondContact CD2-OD2 3.13Å; H147-D157 IonicContact CG-OD2 2.66Å; H147-D157 IonicContact NE2-OD2 3.17Å; A153-D157 WeakPolarHBondContact O-CB 3.3Å; A153-D157 PolarHBondContact O-N 2.93Å; A153-D157 VanDerWaalsContact O-N 3.12Å; M154-D157 PolarHBondContact O-N 3.37Å; D157-R308 IonicContact OD1-CZ 2.9Å; D157-R308 IonicContact OD1-NH1 3.54Å; D157-R308 PolarHBondContact OD1-NH1 2.86Å; D157-R308 IonicContact OD1-NH2 3.54Å; D157-R308 IonicContact OD2-CZ 2.66Å; D157-R308 IonicContact OD2-NH1 2.86Å; D157-R308 PolarHBondContact OD2-NH1 2.85Å; D157-R308 IonicContact OD2-NH2 3.98Å; D157-R308 PolarHBondContact OD2-NH2 3.02Å; D157-P477 HydrophobicContact CB-CG 4.47Å; D157-P477 WeakPolarHBondContact OD1-CG 3.47Å
158L98Very high97.3Very high26 Ų2634.2 Ų34.214%0.13618%0.179CC..Hα-helixtrans-94.1-19.4-168.6-61.3-174.4000115M154 H259 V264M154-L158 HydrophobicContact CE-CD1 3.65Å; M154-L158 HydrophobicContact CG-CD1 3.78Å; M154-L158 HydrophobicContact CG-CG 4.36Å; M154-L158 WeakPolarHBondContact O-CB 3.4Å; M154-L158 WeakPolarHBondContact O-CG 3.27Å; M154-L158 PolarHBondContact O-N 3.04Å; L158-H259 HydrophobicContact CB-CB 4.07Å; L158-H259 HydrophobicContact CD1-CB 4.25Å; L158-H259 PolarHBondContact O-ND1 3.29Å; L158-V264 HydrophobicContact CD1-CG1 4.41Å; L158-V264 HydrophobicContact CD2-CG1 4.33Å; L158-V264 HydrophobicContact CD2-CG2 3.99Å
159L97.9Very high96.8Very high13 Ų1340 Ų407%0.06821%0.206CC..SBendtrans-118.4152.2-173.8-50176.4000110.7G155 I161 Y166 L252 D255G155-L159 WeakPolarHBondContact O-CB 3.36Å; G155-L159 PolarHBondContact O-N 2.99Å; L159-I161 HydrophobicContact CB-CG1 4.24Å; L159-I161 PolarHBondContact O-N 2.9Å; L159-Y166 HydrophobicContact CD1-CE2 4.28Å; L159-L252 HydrophobicContact CD1-CD1 3.42Å; L159-L252 VanDerWaalsContact CD1-CD1 3.42Å; L159-D255 HydrophobicContact CD1-CB 3.95Å; L159-D255 HydrophobicContact CD2-CB 3.88Å
160P96.4Very high95.7Very high104 Ų10441.4 Ų41.468%0.67522%0.215SC*.  trans-7867.6-179.933.7-36.6000111.2
161I97.6Very high94.2Very high18 Ų1845.4 Ų45.49%0.09224%0.244CC..  trans-90.1115.3174.2-58.8175.4000107.9G155 Y156 L159 Y166 L183 L252G155-I161 WeakPolarHBondContact O-CD1 3.35Å; Y156-I161 HydrophobicContact CD1-CB 4.29Å; Y156-I161 HydrophobicContact CD1-CG2 4.03Å; Y156-I161 HydrophobicContact CD2-CD1 3.99Å; Y156-I161 HydrophobicContact CE1-CB 4.41Å; Y156-I161 HydrophobicContact CE1-CG2 3.64Å; Y156-I161 HydrophobicContact CE2-CD1 4.2Å; Y156-I161 HydrophobicContact CE2-CG2 4.24Å; Y156-I161 HydrophobicContact CG-CD1 4.38Å; Y156-I161 HydrophobicContact CG-CG2 4.49Å; L159-I161 HydrophobicContact CB-CG1 4.24Å; L159-I161 PolarHBondContact O-N 2.9Å; I161-Y166 HydrophobicContact CG1-CD2 4.26Å; I161-L183 HydrophobicContact CD1-CD1 3.89Å; I161-L183 HydrophobicContact CG2-CD1 4.41Å; I161-L252 HydrophobicContact CD1-CD1 4.29Å
162E94.3Very high92.4Very high136 Ų13647.1 Ų47.164%0.63626%0.262SS*.BIsolated β-bridgetrans-117.3129.1-179.1-66.7178.3-177.800109.4D164 V165E162-D164 PolarHBondContact O-N 3.5Å; E162-V165 PolarHBondContact N-O 2.99Å; E162-V165 WeakPolarHBondContact O-CB 3.44Å; E162-V165 PolarHBondContact O-N 2.82Å
163N93.9Very high90.2Very high145 Ų14554.2 Ų54.278%0.77530%0.297SS*.THydrogen-bonded Turntrans49.144.8-178.1-58.1-49.3000112.6V165N163-V165 PolarHBondContact O-N 3.28Å; N163-V165 VanDerWaalsContact O-N 3.07Å
164D97.1Very high88.2Confident38 Ų3857.8 Ų57.820%0.20333%0.334CS..THydrogen-bonded Turntrans6211.4-178.1-41.7-48.9000115Y42 Y156 E162 L182 L183Y42-D164 WeakPolarHBondContact CE2-OD2 3.33Å; Y42-D164 PolarHBondContact OH-OD1 3.03Å; Y156-D164 WeakPolarHBondContact OH-CA 3.49Å; Y156-D164 WeakPolarHBondContact OH-CB 3.48Å; Y156-D164 PolarHBondContact OH-OD1 3.4Å; E162-D164 PolarHBondContact O-N 3.5Å; D164-L182 HydrophobicContact CB-CD1 3.96Å; D164-L183 PolarHBondContact O-N 3.18Å
165V97.9Very high86.5Confident37 Ų3763.4 Ų63.422%0.22436%0.364CS..EExtended strand (participates in β ladder)trans-96.4111.9178.3-177.50000110.3E162 N163 K167 E180 V181 L182E162-V165 PolarHBondContact N-O 2.99Å; E162-V165 WeakPolarHBondContact O-CB 3.44Å; E162-V165 PolarHBondContact O-N 2.82Å; N163-V165 PolarHBondContact O-N 3.28Å; N163-V165 VanDerWaalsContact O-N 3.07Å; V165-K167 HydrophobicContact CG1-CG 4.3Å; V165-E180 HydrophobicContact CG1-CB 3.89Å; V165-V181 WeakPolarHBondContact CA-O 3.25Å; V165-L182 HydrophobicContact CG2-CD1 4.13Å
166Y97.7Very high85.2Confident4 Ų466.5 Ų66.52%0.01639%0.386CS..EExtended strand (participates in β ladder)trans-91.5132.4171.1171.1-124.8000110.7L159 I161 Y168 V181 T248 Q251 L252 D255L159-Y166 HydrophobicContact CD1-CE2 4.28Å; I161-Y166 HydrophobicContact CG1-CD2 4.26Å; Y166-Y168 AromaticContact CD1-CD1 3.71Å; Y166-Y168 HydrophobicContact CD1-CD1 3.71Å; Y166-Y168 HydrophobicContact CD1-CE1 4.2Å; Y166-Y168 AromaticContact CE1-CD1 3.31Å; Y166-Y168 HydrophobicContact CE1-CD1 3.31Å; Y166-Y168 AromaticContact CE1-CE1 3.94Å; Y166-Y168 HydrophobicContact CE1-CE1 3.94Å; Y166-Y168 AromaticContact CE1-CG 3.94Å; Y166-Y168 HydrophobicContact CE1-CG 3.94Å; Y166-Y168 AromaticContact CZ-CD1 3.95Å; Y166-V181 PolarHBondContact N-O 3.07Å; Y166-V181 PolarHBondContact O-N 3.17Å; Y166-T248 HydrophobicContact CD1-CG2 4Å; Y166-T248 HydrophobicContact CE1-CG2 4.3Å; Y166-Q251 WeakPolarHBondContact OH-CG 3.38Å; Y166-L252 HydrophobicContact CD1-CB 4.35Å; Y166-L252 HydrophobicContact CD1-CD1 4.08Å; Y166-L252 HydrophobicContact CD2-CD1 3.92Å; Y166-L252 HydrophobicContact CE1-CB 3.82Å; Y166-L252 HydrophobicContact CE1-CD1 3.97Å; Y166-L252 HydrophobicContact CE1-CG 4.45Å; Y166-L252 HydrophobicContact CE2-CD1 3.84Å; Y166-L252 HydrophobicContact CG-CD1 4.05Å; Y166-D255 PolarHBondContact OH-OD2 3.44Å
167K95.9Very high84.4Confident104 Ų10473.6 Ų73.645%0.45241%0.412SS..EExtended strand (participates in β ladder)trans-116.3129180-50.2-167.7-172.4-163.30110.5V165 V178 K179 E180V165-K167 HydrophobicContact CG1-CG 4.3Å; K167-V178 HydrophobicContact CB-CG1 4.35Å; K167-K179 WeakPolarHBondContact CA-O 3.34Å; K167-E180 HydrophobicContact CD-CG 4.05Å; K167-E180 WeakPolarHBondContact CD-OE1 3.49Å; K167-E180 WeakPolarHBondContact CE-OE1 3.49Å; K167-E180 HydrophobicContact CG-CG 4.03Å; K167-E180 IonicContact NZ-OE1 2.68Å; K167-E180 PolarHBondContact NZ-OE1 3.33Å
168Y92.1Very high84Confident9 Ų977.1 Ų77.14%0.03543%0.434CS..EExtended strand (participates in β ladder)trans-144.8154.1175.267-84.3000112.4Y166 K179 V181 T248 Q251Y166-Y168 AromaticContact CD1-CD1 3.71Å; Y166-Y168 HydrophobicContact CD1-CD1 3.71Å; Y166-Y168 HydrophobicContact CD1-CE1 4.2Å; Y166-Y168 AromaticContact CE1-CD1 3.31Å; Y166-Y168 HydrophobicContact CE1-CD1 3.31Å; Y166-Y168 AromaticContact CE1-CE1 3.94Å; Y166-Y168 HydrophobicContact CE1-CE1 3.94Å; Y166-Y168 AromaticContact CE1-CG 3.94Å; Y166-Y168 HydrophobicContact CE1-CG 3.94Å; Y166-Y168 AromaticContact CZ-CD1 3.95Å; Y168-K179 HydrophobicContact CE1-CB 4.38Å; Y168-K179 HydrophobicContact CE1-CD 4.17Å; Y168-K179 HydrophobicContact CE1-CG 4.39Å; Y168-K179 HydrophobicContact CE2-CD 4.34Å; Y168-K179 PolarHBondContact N-O 3.45Å; Y168-K179 PolarHBondContact O-N 2.75Å; Y168-K179 WeakPolarHBondContact OH-CD 3.39Å; Y168-K179 PolarHBondContact OH-NZ 2.83Å; Y168-V181 HydrophobicContact CE1-CG2 3.8Å; Y168-T248 HydrophobicContact CE1-CG2 3.93Å; Y168-T248 WeakPolarHBondContact OH-CA 3.43Å; Y168-T248 PolarHBondContact OH-N 3.04Å; Y168-T248 PolarHBondContact OH-OG1 2.78Å; Y168-Q251 HydrophobicContact CD2-CB 4.11Å; Y168-Q251 HydrophobicContact CD2-CG 3.66Å; Y168-Q251 HydrophobicContact CE2-CB 4.26Å; Y168-Q251 HydrophobicContact CE2-CG 4.3Å; Y168-Q251 HydrophobicContact CG-CB 4.42Å; Y168-Q251 HydrophobicContact CG-CG 3.87Å
169E86.5Confident83.6Confident137 Ų13778.2 Ų78.264%0.6444%0.438SS*.EExtended strand (participates in β ladder)trans-82.8131.1173.4-71.1-169.6-161.800110.8S176 V178E169-S176 PolarHBondContact OE2-OG 3.33Å; E169-V178 HydrophobicContact CG-CG2 4.31Å
170T75.5Confident83.5Confident35 Ų3583.4 Ų83.422%0.21546%0.462CS..EExtended strand (participates in β ladder)trans-125.5133.9172.5-178.90000110.6G172 R177 K179T170-G172 PolarHBondContact O-N 2.93Å; T170-R177 PolarHBondContact N-O 2.88Å; T170-R177 PolarHBondContact O-N 3.46Å; T170-R177 VanDerWaalsContact O-N 3.12Å; T170-K179 HydrophobicContact CG2-CB 4.16Å; T170-K179 HydrophobicContact CG2-CD 4.37Å
171S67Low83.4Confident98 Ų9879.7 Ų79.769%0.68544%0.437SS*.EExtended strand (participates in β ladder)trans-77.787.5172.7-49.40000110
172G60.5Low83.4Confident36 Ų3683.5 Ų83.537%0.37146%0.457SS..  trans-74.8-175.9167.300000112T170 G174T170-G172 PolarHBondContact O-N 2.93Å; G172-G174 VanDerWaalsContact C-N 3.3Å; G172-G174 PolarHBondContact O-N 3.49Å
173M52.8Low83.5Confident152 Ų15277.3 Ų77.375%0.74943%0.429SS*.SBendtrans-54.684.1176.8-74.7173.3119.300112.9K234M173-K234 HydrophobicContact CE-CD 4.39Å; M173-K234 HydrophobicContact CG-CD 4.43Å
174G56.1Low83.5Confident82 Ų8274 Ų7485%0.84541%0.408SS*.SBendtrans98.1-15.5165.400000117.3G172G172-G174 VanDerWaalsContact C-N 3.3Å; G172-G174 PolarHBondContact O-N 3.49Å
175D62.8Low83.4Confident119 Ų11974.5 Ų74.564%0.63641%0.409SS*.SBendtrans-137.2141.4-179.6-119.8-14.2000111.4R177D175-R177 PolarHBondContact O-N 3.06Å
176S71.8Confident83.2Confident67 Ų6778.9 Ų78.947%0.46943%0.432SS..EExtended strand (participates in β ladder)trans-66.9124.7169-168.50000108E169E169-S176 PolarHBondContact OE2-OG 3.33Å
177R82.1Confident83.1Confident164 Ų16479.3 Ų79.362%0.61943%0.434SS*.EExtended strand (participates in β ladder)trans-120.1130.7176.8-65.1-176.1-176-178.2-0.2108.9T170 D175 K179T170-R177 PolarHBondContact N-O 2.88Å; T170-R177 PolarHBondContact O-N 3.46Å; T170-R177 VanDerWaalsContact O-N 3.12Å; D175-R177 PolarHBondContact O-N 3.06Å; R177-K179 PolarHBondContact O-N 3.48Å
178V88.9Confident83Confident95 Ų9580.5 Ų80.558%0.57645%0.445SS*.EExtended strand (participates in β ladder)trans-72.1125.4166.1-177.80000107.5K167 E169K167-V178 HydrophobicContact CB-CG1 4.35Å; E169-V178 HydrophobicContact CG-CG2 4.31Å
179K90.5Very high83.2Confident50 Ų5080.5 Ų80.522%0.21745%0.446CS..EExtended strand (participates in β ladder)trans-111128.3176.5-174.7175.8167.3-164.20108.5K167 Y168 T170 R177 V181 S244K167-K179 WeakPolarHBondContact CA-O 3.34Å; Y168-K179 HydrophobicContact CE1-CB 4.38Å; Y168-K179 HydrophobicContact CE1-CD 4.17Å; Y168-K179 HydrophobicContact CE1-CG 4.39Å; Y168-K179 HydrophobicContact CE2-CD 4.34Å; Y168-K179 PolarHBondContact N-O 3.45Å; Y168-K179 PolarHBondContact O-N 2.75Å; Y168-K179 WeakPolarHBondContact OH-CD 3.39Å; Y168-K179 PolarHBondContact OH-NZ 2.83Å; T170-K179 HydrophobicContact CG2-CB 4.16Å; T170-K179 HydrophobicContact CG2-CD 4.37Å; R177-K179 PolarHBondContact O-N 3.48Å; K179-V181 HydrophobicContact CD-CG2 4.16Å; K179-V181 HydrophobicContact CG-CG2 3.88Å; K179-S244 WeakPolarHBondContact CE-OG 3.39Å; K179-S244 PolarHBondContact NZ-O 2.83Å; K179-S244 PolarHBondContact NZ-OG 3.01Å
180E95Very high83.7Confident122 Ų12274.2 Ų74.257%0.5742%0.416SS*.EExtended strand (participates in β ladder)trans-101.6129.1174-55.5-170.2150.400108.3V165 K167V165-E180 HydrophobicContact CG1-CB 3.89Å; K167-E180 HydrophobicContact CD-CG 4.05Å; K167-E180 WeakPolarHBondContact CD-OE1 3.49Å; K167-E180 WeakPolarHBondContact CE-OE1 3.49Å; K167-E180 HydrophobicContact CG-CG 4.03Å; K167-E180 IonicContact NZ-OE1 2.68Å; K167-E180 PolarHBondContact NZ-OE1 3.33Å
181V95.5Very high84.7Confident26 Ų2674.8 Ų74.816%0.15842%0.42CS..EExtended strand (participates in β ladder)trans-132.8125.6-178.2-172.70000109.4V165 Y166 Y168 K179 T248V165-V181 WeakPolarHBondContact CA-O 3.25Å; Y166-V181 PolarHBondContact N-O 3.07Å; Y166-V181 PolarHBondContact O-N 3.17Å; Y168-V181 HydrophobicContact CE1-CG2 3.8Å; K179-V181 HydrophobicContact CD-CG2 4.16Å; K179-V181 HydrophobicContact CG-CG2 3.88Å; V181-T248 HydrophobicContact CB-CG2 4.08Å; V181-T248 HydrophobicContact CG1-CG2 3.95Å; V181-T248 HydrophobicContact CG2-CG2 4.16Å
182L96.9Very high86.1Confident98 Ų9872.4 Ų72.451%0.51340%0.403SS..EExtended strand (participates in β ladder)trans-77.4124.4172.2-173.571000109.9D164 V165 H184D164-L182 HydrophobicContact CB-CD1 3.96Å; V165-L182 HydrophobicContact CG2-CD1 4.13Å; L182-H184 HydrophobicContact CD2-CB 3.98Å; L182-H184 HydrophobicContact CG-CB 4.04Å; L182-H184 PolarHBondContact O-N 3.29Å
183L96.8Very high87.9Confident6 Ų670.7 Ų70.73%0.03139%0.385CS..  trans-87.594.8174-59178.7000108.9Y156 I161 D164 W190 L252Y156-L183 HydrophobicContact CE2-CD1 4.02Å; I161-L183 HydrophobicContact CD1-CD1 3.89Å; I161-L183 HydrophobicContact CG2-CD1 4.41Å; D164-L183 PolarHBondContact O-N 3.18Å; L183-W190 HydrophobicContact CB-CD2 4.28Å; L183-W190 HydrophobicContact CB-CH2 4.46Å; L183-W190 HydrophobicContact CB-CZ2 4.09Å; L183-W190 HydrophobicContact CD1-CH2 3.85Å; L183-W190 HydrophobicContact CD1-CZ2 4.24Å; L183-W190 HydrophobicContact CD1-CZ3 4.09Å; L183-W190 HydrophobicContact CD2-CD2 4.47Å; L183-W190 HydrophobicContact CD2-CE3 4.19Å; L183-W190 HydrophobicContact CD2-CZ3 4.34Å; L183-L252 HydrophobicContact CD1-CD2 4.2Å; L183-L252 HydrophobicContact CD2-CD2 4.22Å
184H94.3Very high90.1Very high74 Ų7463.7 Ų63.734%0.34335%0.35SS..  trans-134.1165.6-170.1-170.6-109.6000112.5L182 D186 D187L182-H184 HydrophobicContact CD2-CB 3.98Å; L182-H184 HydrophobicContact CG-CB 4.04Å; L182-H184 PolarHBondContact O-N 3.29Å; H184-D186 IonicContact CE1-OD2 3.74Å; H184-D186 PolarHBondContact CE1-OD2 3.12Å; H184-D186 PolarHBondContact ND1-N 2.9Å; H184-D186 IonicContact ND1-OD2 2.69Å; H184-D186 PolarHBondContact ND1-OD2 2.76Å; H184-D186 PolarHBondContact O-N 3.14Å; H184-D187 PolarHBondContact O-N 3.18Å
185E95Very high92.1Very high49 Ų4961.6 Ų61.623%0.22932%0.319CS..THydrogen-bonded Turntrans-61.2-18.1176.4-72-84.4-175.700113.4E43 S44 D187 V191 R194E43-E185 WeakPolarHBondContact CA-OE1 3.18Å; E43-E185 VanDerWaalsContact CB-OE1 3.27Å; E43-E185 WeakPolarHBondContact CB-OE1 3.2Å; S44-E185 PolarHBondContact N-OE1 3.17Å; S44-E185 PolarHBondContact OG-OE1 3.46Å; E185-D187 PolarHBondContact O-N 2.95Å; E185-V191 VanDerWaalsContact OE2-CG2 3.24Å; E185-V191 WeakPolarHBondContact OE2-CG2 3.39Å; E185-R194 IonicContact OE1-CZ 2.66Å; E185-R194 IonicContact OE1-NH1 3.57Å; E185-R194 PolarHBondContact OE1-NH1 3.38Å; E185-R194 IonicContact OE1-NH2 3.34Å; E185-R194 PolarHBondContact OE1-NH2 3.24Å; E185-R194 IonicContact OE2-NH1 3.86Å; E185-R194 IonicContact OE2-NH2 2.76Å
186D93.8Very high93.7Very high130 Ų13059 Ų5970%0.69530%0.302SS*.THydrogen-bonded Turntrans-72.2-6.8172.4-63.9-46000113.4H184 K245H184-D186 IonicContact CE1-OD2 3.74Å; H184-D186 PolarHBondContact CE1-OD2 3.12Å; H184-D186 PolarHBondContact ND1-N 2.9Å; H184-D186 IonicContact ND1-OD2 2.69Å; H184-D186 PolarHBondContact ND1-OD2 2.76Å; H184-D186 PolarHBondContact O-N 3.14Å; D186-K245 PolarHBondContact O-NZ 3.06Å; D186-K245 VanDerWaalsContact O-NZ 3.1Å
187D95.1Very high95Very high13 Ų1357 Ų577%0.0729%0.285CS..  trans-101.391.4171.2-165.34.2000112.6H184 E185 L189 W190 V191 K245 H249H184-D187 PolarHBondContact O-N 3.18Å; E185-D187 PolarHBondContact O-N 2.95Å; D187-L189 PolarHBondContact O-N 3.13Å; D187-L189 PolarHBondContact OD1-N 3.25Å; D187-W190 HydrophobicContact CB-CB 3.84Å; D187-W190 WeakPolarHBondContact O-CA 3.47Å; D187-W190 VanDerWaalsContact O-CB 3.25Å; D187-W190 WeakPolarHBondContact O-CB 3.4Å; D187-W190 PolarHBondContact O-N 2.98Å; D187-V191 PolarHBondContact O-N 2.56Å; D187-K245 WeakPolarHBondContact OD1-CD 3.48Å; D187-K245 VanDerWaalsContact OD1-CE 3.29Å; D187-K245 WeakPolarHBondContact OD1-CE 3.02Å; D187-K245 IonicContact OD1-NZ 3.51Å; D187-K245 PolarHBondContact OD1-NZ 3.1Å; D187-H249 IonicContact OD2-CD2 3.42Å; D187-H249 IonicContact OD2-CE1 3.32Å; D187-H249 IonicContact OD2-NE2 3.7Å; D187-H249 PolarHBondContact OD2-NE2 2.96Å
188D94.4Very high95.7Very high128 Ų12849.6 Ų49.668%0.68426%0.257SS*.Hα-helixtrans-48.5-34.2175.3-57.4-39.9000113.5S192D188-S192 WeakPolarHBondContact O-CB 3.42Å; D188-S192 PolarHBondContact O-N 2.86Å; D188-S192 PolarHBondContact O-OG 3.16Å
189L94.7Very high95.9Very high9 Ų947.6 Ų47.65%0.04725%0.251CS..Hα-helixtrans-68.1-44.9177.6-172.955.6000110.3D187 S192 L193 Y246 H249D187-L189 PolarHBondContact O-N 3.13Å; D187-L189 PolarHBondContact OD1-N 3.25Å; L189-S192 PolarHBondContact O-N 2.93Å; L189-S192 PolarHBondContact O-OG 3.03Å; L189-L193 HydrophobicContact CD1-CD1 3.59Å; L189-L193 HydrophobicContact CD1-CG 4.06Å; L189-L193 HydrophobicContact CG-CD1 3.65Å; L189-L193 HydrophobicContact CG-CG 4.47Å; L189-L193 WeakPolarHBondContact O-CB 3.38Å; L189-L193 WeakPolarHBondContact O-CD1 3.34Å; L189-L193 WeakPolarHBondContact O-CG 3.33Å; L189-L193 PolarHBondContact O-N 3.14Å; L189-L193 VanDerWaalsContact O-N 3.08Å; L189-Y246 HydrophobicContact CD1-CE1 4.37Å; L189-Y246 HydrophobicContact CD2-CD1 3.56Å; L189-Y246 HydrophobicContact CD2-CE1 3.81Å; L189-Y246 HydrophobicContact CD2-CG 4.05Å; L189-H249 HydrophobicContact CD2-CB 4.34Å; L189-H249 VanDerWaalsContact CD2-CD2 3.43Å; L189-H249 WeakPolarHBondContact CD2-CD2 3.37Å
190W97.5Very high96.2Very high5 Ų549 Ų492%0.01926%0.258CS..Hα-helixtrans-57.8-50.5173175.1-114.9000111.7F151 Q152 Y156 L183 D187 S192 L193 R194 H249 L252F151-W190 HydrophobicContact CD1-CE3 4.28Å; F151-W190 AromaticContact CD1-CZ3 3.97Å; F151-W190 HydrophobicContact CD1-CZ3 3.97Å; F151-W190 HydrophobicContact CE1-CE3 4.17Å; F151-W190 HydrophobicContact CE1-CZ3 4.02Å; Q152-W190 HydrophobicContact CB-CH2 3.69Å; Q152-W190 HydrophobicContact CB-CZ2 3.82Å; Q152-W190 HydrophobicContact CG-CH2 3.97Å; Q152-W190 HydrophobicContact CG-CZ2 3.72Å; Y156-W190 HydrophobicContact CE2-CH2 4.06Å; Y156-W190 HydrophobicContact CE2-CZ2 4.05Å; L183-W190 HydrophobicContact CB-CD2 4.28Å; L183-W190 HydrophobicContact CB-CH2 4.46Å; L183-W190 HydrophobicContact CB-CZ2 4.09Å; L183-W190 HydrophobicContact CD1-CH2 3.85Å; L183-W190 HydrophobicContact CD1-CZ2 4.24Å; L183-W190 HydrophobicContact CD1-CZ3 4.09Å; L183-W190 HydrophobicContact CD2-CD2 4.47Å; L183-W190 HydrophobicContact CD2-CE3 4.19Å; L183-W190 HydrophobicContact CD2-CZ3 4.34Å; D187-W190 HydrophobicContact CB-CB 3.84Å; D187-W190 WeakPolarHBondContact O-CA 3.47Å; D187-W190 VanDerWaalsContact O-CB 3.25Å; D187-W190 WeakPolarHBondContact O-CB 3.4Å; D187-W190 PolarHBondContact O-N 2.98Å; W190-S192 VanDerWaalsContact C-N 3.25Å; W190-S192 PolarHBondContact O-N 3.21Å; W190-L193 PolarHBondContact O-N 2.95Å; W190-R194 HydrophobicContact CD2-CB 4.18Å; W190-R194 HydrophobicContact CE3-CB 4.47Å; W190-R194 HydrophobicContact CH2-CB 4.46Å; W190-R194 HydrophobicContact CZ2-CB 4.13Å; W190-R194 WeakPolarHBondContact O-CB 3.22Å; W190-R194 PolarHBondContact O-N 2.85Å; W190-H249 AromaticContact CE3-CE1 3.76Å; W190-L252 HydrophobicContact CZ3-CD2 3.87Å
191V97.6Very high96.2Very high48 Ų4843.1 Ų43.129%0.29123%0.231SC..Hα-helixtrans-57.8-39.4179.8178.80000111.3E185 D187E185-V191 VanDerWaalsContact OE2-CG2 3.24Å; E185-V191 WeakPolarHBondContact OE2-CG2 3.39Å; D187-V191 PolarHBondContact O-N 2.56Å
192S96.6Very high95.9Very high47 Ų4744.1 Ų44.133%0.32924%0.239SC..Hα-helixtrans-73.7-22.6178.278.70000114.6D188 L189 W190 K196D188-S192 WeakPolarHBondContact O-CB 3.42Å; D188-S192 PolarHBondContact O-N 2.86Å; D188-S192 PolarHBondContact O-OG 3.16Å; L189-S192 PolarHBondContact O-N 2.93Å; L189-S192 PolarHBondContact O-OG 3.03Å; W190-S192 VanDerWaalsContact C-N 3.25Å; W190-S192 PolarHBondContact O-N 3.21Å; S192-K196 WeakPolarHBondContact O-CE 3.31Å
193L97.8Very high95.6Very high0 Ų046.5 Ų46.50%025%0.248CC..Hα-helixtrans-105.6-29.1-172.9-66171.9000113.9F151 L189 W190 H195 K196 V201 E204 V205 H249F151-L193 WeakPolarHBondContact CB-O 3.49Å; F151-L193 HydrophobicContact CD1-CB 3.7Å; F151-L193 HydrophobicContact CE1-CB 4.03Å; F151-L193 HydrophobicContact CE1-CD1 4.21Å; L189-L193 HydrophobicContact CD1-CD1 3.59Å; L189-L193 HydrophobicContact CD1-CG 4.06Å; L189-L193 HydrophobicContact CG-CD1 3.65Å; L189-L193 HydrophobicContact CG-CG 4.47Å; L189-L193 WeakPolarHBondContact O-CB 3.38Å; L189-L193 WeakPolarHBondContact O-CD1 3.34Å; L189-L193 WeakPolarHBondContact O-CG 3.33Å; L189-L193 PolarHBondContact O-N 3.14Å; L189-L193 VanDerWaalsContact O-N 3.08Å; W190-L193 PolarHBondContact O-N 2.95Å; L193-H195 PolarHBondContact O-N 3.34Å; L193-K196 HydrophobicContact CD2-CD 4.08Å; L193-K196 WeakPolarHBondContact O-CB 3.3Å; L193-K196 PolarHBondContact O-N 2.56Å; L193-V201 HydrophobicContact CD2-CG1 4.4Å; L193-E204 HydrophobicContact CD2-CB 4.06Å; L193-E204 HydrophobicContact CD2-CG 3.71Å; L193-V205 HydrophobicContact CD1-CG2 3.41Å; L193-V205 VanDerWaalsContact CD1-CG2 3.41Å; L193-V205 HydrophobicContact CD2-CG2 4.1Å; L193-V205 HydrophobicContact CG-CG2 4.42Å; L193-H249 HydrophobicContact CD1-CB 4.05Å
194R98.3Very high95.4Very high5 Ų547.8 Ų47.82%0.01925%0.254CS..THydrogen-bonded Turntrans-53.2-32.3-166.860.7169.1-175.7-146.3-10.6114.6E43 F151 Q152 E185 W190 Y456E43-R194 VanDerWaalsContact CD-CZ 3.48Å; E43-R194 IonicContact OE1-CZ 3.64Å; E43-R194 IonicContact OE1-NE 3.54Å; E43-R194 IonicContact OE1-NH1 2.84Å; E43-R194 PolarHBondContact OE1-NH1 3.37Å; E43-R194 IonicContact OE2-CZ 3.73Å; E43-R194 IonicContact OE2-NE 3.79Å; E43-R194 IonicContact OE2-NH1 3.81Å; E43-R194 PolarHBondContact OE2-NH1 2.97Å; E43-R194 IonicContact OE2-NH2 2.76Å; F151-R194 PolarHBondContact N-O 2.99Å; Q152-R194 HydrophobicContact CB-CB 3.84Å; Q152-R194 VanDerWaalsContact CB-O 3.3Å; Q152-R194 WeakPolarHBondContact CB-O 3.14Å; Q152-R194 PolarHBondContact N-O 3.12Å; E185-R194 IonicContact OE1-CZ 2.66Å; E185-R194 IonicContact OE1-NH1 3.57Å; E185-R194 PolarHBondContact OE1-NH1 3.38Å; E185-R194 IonicContact OE1-NH2 3.34Å; E185-R194 PolarHBondContact OE1-NH2 3.24Å; E185-R194 IonicContact OE2-NH1 3.86Å; E185-R194 IonicContact OE2-NH2 2.76Å; W190-R194 HydrophobicContact CD2-CB 4.18Å; W190-R194 HydrophobicContact CE3-CB 4.47Å; W190-R194 HydrophobicContact CH2-CB 4.46Å; W190-R194 HydrophobicContact CZ2-CB 4.13Å; W190-R194 WeakPolarHBondContact O-CB 3.22Å; W190-R194 PolarHBondContact O-N 2.85Å; R194-Y456 VanDerWaalsContact NH2-CE1 3.3Å; R194-Y456 PolarHBondContact NH2-OH 2.77Å
195H98.2Very high95.3Very high39 Ų3944.3 Ų44.318%0.18124%0.237CC..THydrogen-bonded Turntrans-102-1.1-178.8-60.1-29.8000114.2Q152 L193 R453 Y456Q152-H195 PolarHBondContact OE1-CE1 2.76Å; L193-H195 PolarHBondContact O-N 3.34Å; H195-R453 HydrophobicContact CB-CG 3.9Å; H195-Y456 AromaticContact CD2-CD2 3.76Å; H195-Y456 AromaticContact CD2-CG 3.82Å; H195-Y456 AromaticContact CE1-CD2 3.88Å; H195-Y456 AromaticContact CE1-CE2 3.99Å; H195-Y456 AromaticContact NE2-CD2 3.07Å; H195-Y456 WeakPolarHBondContact NE2-CD2 3.1Å; H195-Y456 AromaticContact NE2-CE2 3.31Å; H195-Y456 VanDerWaalsContact NE2-CE2 3.31Å; H195-Y456 WeakPolarHBondContact NE2-CE2 3.32Å; H195-Y456 AromaticContact NE2-CG 3.56Å; H195-Y456 AromaticContact NE2-CZ 3.99Å
196K97.8Very high94.9Very high64 Ų6444 Ų4428%0.27824%0.239SC..SBendtrans-75.7150176-71.5179.4171.9-81.90110.8T150 F151 S192 L193 V201 E204T150-K196 CarbonylContact C-O 3.45Å; T150-K196 VanDerWaalsContact CA-O 3.29Å; T150-K196 WeakPolarHBondContact CA-O 3.31Å; F151-K196 PolarHBondContact N-O 3.02Å; S192-K196 WeakPolarHBondContact O-CE 3.31Å; L193-K196 HydrophobicContact CD2-CD 4.08Å; L193-K196 WeakPolarHBondContact O-CB 3.3Å; L193-K196 PolarHBondContact O-N 2.56Å; K196-V201 HydrophobicContact CB-CG2 4.13Å; K196-E204 HydrophobicContact CD-CG 4.14Å
197H97.8Very high94.7Very high24 Ų2443 Ų4311%0.11123%0.226CC..BIsolated β-bridgetrans-68.1139.5173.1-172.2-91.6000110.6A199 E200 V201 Y375 S378H197-A199 VanDerWaalsContact ND1-CB 3.3Å; H197-A199 WeakPolarHBondContact ND1-CB 3.44Å; H197-A199 PolarHBondContact ND1-N 3.4Å; H197-A199 PolarHBondContact O-N 3.42Å; H197-A199 VanDerWaalsContact O-N 3.08Å; H197-E200 PolarHBondContact O-N 3.14Å; H197-V201 PolarHBondContact O-N 3.01Å; H197-Y375 HydrophobicContact CB-CD2 4.14Å; H197-Y375 HydrophobicContact CB-CE2 3.77Å; H197-Y375 AromaticContact CD2-CD2 3.68Å; H197-Y375 AromaticContact CE1-CD1 3.86Å; H197-Y375 AromaticContact CE1-CD2 3.92Å; H197-Y375 AromaticContact CE1-CG 3.76Å; H197-Y375 AromaticContact CG-CD2 3.6Å; H197-Y375 AromaticContact CG-CE2 3.57Å; H197-Y375 AromaticContact ND1-CD2 3.75Å; H197-Y375 AromaticContact ND1-CE1 3.99Å; H197-Y375 AromaticContact ND1-CE2 3.6Å; H197-Y375 AromaticContact ND1-CZ 3.73Å; H197-Y375 AromaticContact NE2-CD2 3.89Å; H197-Y375 AromaticContact NE2-CG 3.79Å; H197-S378 PolarHBondContact NE2-OG 2.86Å
198I96.9Very high94.5Very high9 Ų944.2 Ų44.25%0.04623%0.231CC..Hα-helixtrans-55.8-32.3-173.9-171.562.9000113.2L149 F151 M154 E200 V201 A253 C256 M257L149-I198 HydrophobicContact CB-CG2 4.25Å; L149-I198 PolarHBondContact O-N 3.35Å; F151-I198 HydrophobicContact CD2-CD1 3.97Å; F151-I198 HydrophobicContact CE2-CD1 4.35Å; M154-I198 HydrophobicContact CE-CG1 4.37Å; M154-I198 HydrophobicContact CE-CG2 4.43Å; M154-I198 HydrophobicContact SD-CB 3.66Å; M154-I198 HydrophobicContact SD-CD1 4.22Å; M154-I198 HydrophobicContact SD-CG1 3.69Å; M154-I198 HydrophobicContact SD-CG2 3.76Å; I198-E200 PolarHBondContact O-N 2.84Å; I198-V201 HydrophobicContact CD1-CB 4.41Å; I198-V201 PolarHBondContact O-N 3.12Å; I198-A253 HydrophobicContact CD1-CB 4.21Å; I198-C256 HydrophobicContact CD1-CB 3.94Å; I198-C256 HydrophobicContact CG1-CB 4.47Å; I198-M257 HydrophobicContact CG1-CG 4.15Å; I198-M257 HydrophobicContact CG1-SD 3.68Å; I198-M257 HydrophobicContact CG2-SD 4.28Å
199A94.4Very high94.1Very high54 Ų5438.1 Ų38.145%0.44620%0.198SC..Hα-helixtrans-60.5-25176.800000113.7H197 Y375H197-A199 VanDerWaalsContact ND1-CB 3.3Å; H197-A199 WeakPolarHBondContact ND1-CB 3.44Å; H197-A199 PolarHBondContact ND1-N 3.4Å; H197-A199 PolarHBondContact O-N 3.42Å; H197-A199 VanDerWaalsContact O-N 3.08Å; A199-Y375 HydrophobicContact CB-CE1 4.06Å
200E95Very high93.7Very high78 Ų7842.7 Ų42.736%0.36422%0.218SC..Hα-helixtrans-97.3-25.9-180-59.9178.5-157.700112.6H197 I198 S202 Q203 E204 Y375H197-E200 PolarHBondContact O-N 3.14Å; I198-E200 PolarHBondContact O-N 2.84Å; E200-S202 PolarHBondContact O-N 3.36Å; E200-Q203 PolarHBondContact O-N 3.32Å; E200-E204 WeakPolarHBondContact O-CB 3.44Å; E200-E204 PolarHBondContact O-N 3.22Å; E200-Y375 WeakPolarHBondContact CG-OH 3.36Å; E200-Y375 PolarHBondContact OE1-OH 3.47Å
201V95.3Very high93.2Very high0 Ų047 Ų470%024%0.238CC..Hα-helixtrans-57.6-51.9-169.9172.60000112F151 L193 K196 H197 I198 Q203 E204 V205 A253F151-V201 HydrophobicContact CB-CG2 3.8Å; F151-V201 HydrophobicContact CD1-CG1 4.04Å; F151-V201 HydrophobicContact CD1-CG2 4.3Å; F151-V201 HydrophobicContact CD2-CG1 4.02Å; F151-V201 HydrophobicContact CD2-CG2 4.16Å; F151-V201 HydrophobicContact CE1-CG1 3.92Å; F151-V201 HydrophobicContact CE2-CG1 3.91Å; F151-V201 HydrophobicContact CG-CG1 4.08Å; F151-V201 HydrophobicContact CG-CG2 3.85Å; F151-V201 HydrophobicContact CZ-CG1 3.84Å; L193-V201 HydrophobicContact CD2-CG1 4.4Å; K196-V201 HydrophobicContact CB-CG2 4.13Å; H197-V201 PolarHBondContact O-N 3.01Å; I198-V201 HydrophobicContact CD1-CB 4.41Å; I198-V201 PolarHBondContact O-N 3.12Å; V201-Q203 VanDerWaalsContact C-N 3.28Å; V201-Q203 PolarHBondContact O-N 3.06Å; V201-E204 PolarHBondContact O-N 3.18Å; V201-E204 VanDerWaalsContact O-N 3.15Å; V201-V205 HydrophobicContact CG1-CG2 4.08Å; V201-V205 VanDerWaalsContact O-CG2 3.22Å; V201-V205 WeakPolarHBondContact O-CG2 3.09Å; V201-V205 PolarHBondContact O-N 2.78Å; V201-A253 HydrophobicContact CG1-CB 4Å
202S89.4Confident92.7Very high47 Ų4746.1 Ų46.133%0.32923%0.23SC..Hα-helixtrans-62.5-36.7-177.2-53.80000112.6E200 T206E200-S202 PolarHBondContact O-N 3.36Å; S202-T206 WeakPolarHBondContact O-CB 3.5Å; S202-T206 PolarHBondContact O-N 3.32Å; S202-T206 VanDerWaalsContact O-N 3.17Å; S202-T206 PolarHBondContact O-OG1 2.63Å
203Q90.3Very high92Very high148 Ų14843.9 Ų43.969%0.69222%0.215SC*.Hα-helixtrans-67.8-43.9176.4-63-174.92.700110.5E200 V201 T206 R207E200-Q203 PolarHBondContact O-N 3.32Å; V201-Q203 VanDerWaalsContact C-N 3.28Å; V201-Q203 PolarHBondContact O-N 3.06Å; Q203-T206 PolarHBondContact O-N 3.02Å; Q203-R207 WeakPolarHBondContact O-CB 3.47Å; Q203-R207 PolarHBondContact O-N 3.09Å
204E93.6Very high91.3Very high33 Ų3347.4 Ų47.415%0.15424%0.24CC..Hα-helixtrans-66.4-43.6-179.3-176.656.7-160.700112.4L193 K196 E200 V201 T206 R207 Q208L193-E204 HydrophobicContact CD2-CB 4.06Å; L193-E204 HydrophobicContact CD2-CG 3.71Å; K196-E204 HydrophobicContact CD-CG 4.14Å; E200-E204 WeakPolarHBondContact O-CB 3.44Å; E200-E204 PolarHBondContact O-N 3.22Å; V201-E204 PolarHBondContact O-N 3.18Å; V201-E204 VanDerWaalsContact O-N 3.15Å; E204-T206 VanDerWaalsContact C-N 3.31Å; E204-T206 PolarHBondContact O-N 2.73Å; E204-R207 WeakPolarHBondContact O-CB 3.33Å; E204-R207 PolarHBondContact O-N 2.95Å; E204-R207 IonicContact OE1-CZ 3.63Å; E204-R207 IonicContact OE1-NE 2.87Å; E204-R207 IonicContact OE1-NH2 3.5Å; E204-R207 PolarHBondContact OE1-NH2 3.06Å; E204-R207 IonicContact OE2-CZ 3.78Å; E204-R207 IonicContact OE2-NE 3.48Å; E204-R207 PolarHBondContact OE2-NE 3.39Å; E204-R207 IonicContact OE2-NH2 3.76Å; E204-Q208 WeakPolarHBondContact O-CG 3.42Å; E204-Q208 PolarHBondContact O-N 2.97Å; E204-Q208 PolarHBondContact OE1-NE2 2.98Å
205V90.9Very high90.7Very high0 Ų050.8 Ų50.80%026%0.264CS..Hα-helixtrans-59.9-44.2174.5178.80000110.6L193 V201 Q208 L209 Y246 H249 L250L193-V205 HydrophobicContact CD1-CG2 3.41Å; L193-V205 VanDerWaalsContact CD1-CG2 3.41Å; L193-V205 HydrophobicContact CD2-CG2 4.1Å; L193-V205 HydrophobicContact CG-CG2 4.42Å; V201-V205 HydrophobicContact CG1-CG2 4.08Å; V201-V205 VanDerWaalsContact O-CG2 3.22Å; V201-V205 WeakPolarHBondContact O-CG2 3.09Å; V201-V205 PolarHBondContact O-N 2.78Å; V205-Q208 PolarHBondContact O-N 2.95Å; V205-L209 WeakPolarHBondContact O-CB 3.24Å; V205-L209 PolarHBondContact O-N 3.41Å; V205-Y246 HydrophobicContact CG1-CD1 4.05Å; V205-H249 HydrophobicContact CG1-CB 4.44Å; V205-H249 HydrophobicContact CG2-CB 4.05Å; V205-L250 HydrophobicContact CB-CD2 4Å; V205-L250 HydrophobicContact CB-CG 4.5Å; V205-L250 HydrophobicContact CG1-CD2 3.66Å; V205-L250 HydrophobicContact CG1-CG 3.63Å
206T87.6Confident90Very high44 Ų4453.3 Ų53.327%0.2727%0.274SS..Hα-helixtrans-66.7-38.9178.9-560000111.6S202 Q203 E204 L209 K210S202-T206 WeakPolarHBondContact O-CB 3.5Å; S202-T206 PolarHBondContact O-N 3.32Å; S202-T206 VanDerWaalsContact O-N 3.17Å; S202-T206 PolarHBondContact O-OG1 2.63Å; Q203-T206 PolarHBondContact O-N 3.02Å; E204-T206 VanDerWaalsContact C-N 3.31Å; E204-T206 PolarHBondContact O-N 2.73Å; T206-L209 PolarHBondContact O-N 3.26Å; T206-K210 WeakPolarHBondContact O-CB 3.35Å; T206-K210 PolarHBondContact O-N 3.07Å
207R90.1Very high88.7Confident109 Ų10961.6 Ų61.641%0.41130%0.304SS..Hα-helixtrans-61-52.4175.4-172.9-170.771.677.22.1110.9Q203 E204 L209 K210 E211Q203-R207 WeakPolarHBondContact O-CB 3.47Å; Q203-R207 PolarHBondContact O-N 3.09Å; E204-R207 WeakPolarHBondContact O-CB 3.33Å; E204-R207 PolarHBondContact O-N 2.95Å; E204-R207 IonicContact OE1-CZ 3.63Å; E204-R207 IonicContact OE1-NE 2.87Å; E204-R207 IonicContact OE1-NH2 3.5Å; E204-R207 PolarHBondContact OE1-NH2 3.06Å; E204-R207 IonicContact OE2-CZ 3.78Å; E204-R207 IonicContact OE2-NE 3.48Å; E204-R207 PolarHBondContact OE2-NE 3.39Å; E204-R207 IonicContact OE2-NH2 3.76Å; R207-L209 VanDerWaalsContact C-N 3.31Å; R207-L209 PolarHBondContact O-N 3.12Å; R207-K210 WeakPolarHBondContact O-CB 3.28Å; R207-K210 PolarHBondContact O-N 3.33Å; R207-K210 VanDerWaalsContact O-N 3.16Å; R207-E211 IonicContact CZ-OE1 3.03Å; R207-E211 IonicContact CZ-OE2 3.88Å; R207-E211 IonicContact NH1-OE1 2.62Å; R207-E211 PolarHBondContact NH1-OE1 3.05Å; R207-E211 IonicContact NH1-OE2 2.93Å; R207-E211 PolarHBondContact NH1-OE2 2.86Å; R207-E211 PolarHBondContact O-N 3.46Å
208Q90.4Very high87.2Confident37 Ų3762.2 Ų62.217%0.17331%0.307CS..Hα-helixtrans-62.6-37.8179.2-69.3-171.233.500111.9E204 V205 K210 E211 F212 Y246E204-Q208 WeakPolarHBondContact O-CG 3.42Å; E204-Q208 PolarHBondContact O-N 2.97Å; E204-Q208 PolarHBondContact OE1-NE2 2.98Å; V205-Q208 PolarHBondContact O-N 2.95Å; Q208-K210 PolarHBondContact O-N 3.34Å; Q208-E211 PolarHBondContact O-N 2.84Å; Q208-F212 WeakPolarHBondContact O-CB 3.1Å; Q208-F212 PolarHBondContact O-N 3.5Å; Q208-Y246 HydrophobicContact CB-CE1 3.79Å; Q208-Y246 PolarHBondContact O-OH 3.22Å
209L87Confident85.6Confident1 Ų169.9 Ų69.91%0.00535%0.349CS..Hα-helixtrans-62.9-39.9174.517861.6000112.5V205 T206 R207 F212 S213 T224 L229 L243 Y246V205-L209 WeakPolarHBondContact O-CB 3.24Å; V205-L209 PolarHBondContact O-N 3.41Å; T206-L209 PolarHBondContact O-N 3.26Å; R207-L209 VanDerWaalsContact C-N 3.31Å; R207-L209 PolarHBondContact O-N 3.12Å; L209-F212 PolarHBondContact O-N 2.99Å; L209-S213 WeakPolarHBondContact O-CB 3.41Å; L209-S213 PolarHBondContact O-N 3.47Å; L209-S213 PolarHBondContact O-OG 3.4Å; L209-T224 HydrophobicContact CD2-CG2 3.58Å; L209-T224 HydrophobicContact CG-CG2 4.43Å; L209-L229 HydrophobicContact CD1-CD1 3.69Å; L209-L229 HydrophobicContact CD2-CD1 3.44Å; L209-L229 VanDerWaalsContact CD2-CD1 3.44Å; L209-L229 HydrophobicContact CG-CD1 4.22Å; L209-L243 HydrophobicContact CD1-CD2 3.91Å; L209-Y246 HydrophobicContact CB-CD1 3.73Å; L209-Y246 HydrophobicContact CB-CE1 3.92Å; L209-Y246 HydrophobicContact CB-CG 4.2Å; L209-Y246 HydrophobicContact CD1-CD1 4.23Å; L209-Y246 HydrophobicContact CD1-CD2 3.86Å; L209-Y246 HydrophobicContact CD1-CE2 4.32Å; L209-Y246 HydrophobicContact CD1-CG 3.82Å; L209-Y246 HydrophobicContact CG-CD1 4.5Å
210K85.3Confident84Confident105 Ų10568.8 Ų68.846%0.45734%0.336SS..Hα-helixtrans-66.6-42.7176.5-172176.9-177.1177.40111.2T206 R207 Q208 S213 S214T206-K210 WeakPolarHBondContact O-CB 3.35Å; T206-K210 PolarHBondContact O-N 3.07Å; R207-K210 WeakPolarHBondContact O-CB 3.28Å; R207-K210 PolarHBondContact O-N 3.33Å; R207-K210 VanDerWaalsContact O-N 3.16Å; Q208-K210 PolarHBondContact O-N 3.34Å; K210-S213 PolarHBondContact O-N 2.87Å; K210-S214 WeakPolarHBondContact O-CB 3.36Å; K210-S214 PolarHBondContact O-N 3.07Å; K210-S214 PolarHBondContact O-OG 3.5Å
211E87.6Confident82.3Confident96 Ų9667.6 Ų67.645%0.44935%0.345SS..Hα-helixtrans-61.1-47.1174.8-74.7174.3-175.500111.2R207 Q208 S213 S214 S215R207-E211 IonicContact CZ-OE1 3.03Å; R207-E211 IonicContact CZ-OE2 3.88Å; R207-E211 IonicContact NH1-OE1 2.62Å; R207-E211 PolarHBondContact NH1-OE1 3.05Å; R207-E211 IonicContact NH1-OE2 2.93Å; R207-E211 PolarHBondContact NH1-OE2 2.86Å; R207-E211 PolarHBondContact O-N 3.46Å; Q208-E211 PolarHBondContact O-N 2.84Å; E211-S213 PolarHBondContact O-N 3.16Å; E211-S214 PolarHBondContact O-N 3.28Å; E211-S214 PolarHBondContact O-OG 2.96Å; E211-S215 WeakPolarHBondContact O-CB 3.3Å; E211-S215 PolarHBondContact O-N 3.42Å
212F86.1Confident80.4Confident28 Ų2876.6 Ų76.612%0.12339%0.387CS..Hα-helixtrans-55.4-50.9173.7178.6-96.9000111.5Q208 L209 S214 S215 K216 Y239 E242 L243 Y246Q208-F212 WeakPolarHBondContact O-CB 3.1Å; Q208-F212 PolarHBondContact O-N 3.5Å; L209-F212 PolarHBondContact O-N 2.99Å; F212-S214 PolarHBondContact O-N 3.36Å; F212-S215 PolarHBondContact O-N 2.95Å; F212-S215 PolarHBondContact O-OG 3.38Å; F212-K216 HydrophobicContact CE1-CG 4.43Å; F212-K216 HydrophobicContact CE2-CG 4.49Å; F212-K216 HydrophobicContact CZ-CG 4.29Å; F212-K216 WeakPolarHBondContact O-CG 3.46Å; F212-K216 PolarHBondContact O-N 3.37Å; F212-Y239 HydrophobicContact CZ-CD1 4.1Å; F212-Y239 HydrophobicContact CZ-CG 4.03Å; F212-E242 HydrophobicContact CE2-CB 4.04Å; F212-E242 HydrophobicContact CE2-CG 4.21Å; F212-E242 HydrophobicContact CZ-CB 3.86Å; F212-E242 HydrophobicContact CZ-CG 4.34Å; F212-L243 HydrophobicContact CD1-CD2 4.33Å; F212-L243 HydrophobicContact CE1-CD2 4.06Å; F212-L243 HydrophobicContact CE1-CG 4.37Å; F212-Y246 HydrophobicContact CB-CE2 4.26Å; F212-Y246 HydrophobicContact CD1-CE2 4.47Å; F212-Y246 HydrophobicContact CG-CE2 4.19Å
213S83Confident78.9Confident0 Ų083 Ų830%041%0.409CS..Hα-helixtrans-59.4-46.2-179.9-59.10000112.1L209 K210 E211 S215 K216 R217 M218 T220 M232L209-S213 WeakPolarHBondContact O-CB 3.41Å; L209-S213 PolarHBondContact O-N 3.47Å; L209-S213 PolarHBondContact O-OG 3.4Å; K210-S213 PolarHBondContact O-N 2.87Å; E211-S213 PolarHBondContact O-N 3.16Å; S213-S215 PolarHBondContact O-N 3.44Å; S213-K216 CarbonylContact O-C 3.58Å; S213-K216 PolarHBondContact O-N 3.47Å; S213-R217 PolarHBondContact O-N 2.82Å; S213-M218 VanDerWaalsContact O-CB 3.32Å; S213-M218 WeakPolarHBondContact O-CB 3.44Å; S213-M218 PolarHBondContact O-N 3.29Å; S213-T220 WeakPolarHBondContact OG-CG2 3.24Å; S213-M232 WeakPolarHBondContact OG-CE 3.22Å
214S82.8Confident77.7Confident75 Ų7576.8 Ų76.852%0.52438%0.381SS..Hα-helixtrans-63.1-40.7178.272.80000112.3K210 E211 F212 K216 R217K210-S214 WeakPolarHBondContact O-CB 3.36Å; K210-S214 PolarHBondContact O-N 3.07Å; K210-S214 PolarHBondContact O-OG 3.5Å; E211-S214 PolarHBondContact O-N 3.28Å; E211-S214 PolarHBondContact O-OG 2.96Å; F212-S214 PolarHBondContact O-N 3.36Å; S214-K216 PolarHBondContact O-N 3.45Å; S214-R217 PolarHBondContact O-N 3.03Å
215S85.8Confident76.4Confident76 Ų7678.5 Ų78.553%0.53139%0.394SS..Hα-helixtrans-62.6-27.6177.881.10000112.7E211 F212 S213E211-S215 WeakPolarHBondContact O-CB 3.3Å; E211-S215 PolarHBondContact O-N 3.42Å; F212-S215 PolarHBondContact O-N 2.95Å; F212-S215 PolarHBondContact O-OG 3.38Å; S213-S215 PolarHBondContact O-N 3.44Å
216K82.4Confident75.3Confident91 Ų9180.9 Ų80.940%0.39641%0.406SS..THydrogen-bonded Turntrans-95.814.5177-53.9-49.4179.8-173.60113F212 S213 S214 M218 Y239F212-K216 HydrophobicContact CE1-CG 4.43Å; F212-K216 HydrophobicContact CE2-CG 4.49Å; F212-K216 HydrophobicContact CZ-CG 4.29Å; F212-K216 WeakPolarHBondContact O-CG 3.46Å; F212-K216 PolarHBondContact O-N 3.37Å; S213-K216 CarbonylContact O-C 3.58Å; S213-K216 PolarHBondContact O-N 3.47Å; S214-K216 PolarHBondContact O-N 3.45Å; K216-M218 VanDerWaalsContact C-N 3.32Å; K216-M218 HydrophobicContact CB-CG 4.42Å; K216-M218 PolarHBondContact O-N 3.24Å; K216-Y239 HydrophobicContact CB-CE2 4.27Å; K216-Y239 HydrophobicContact CD-CE1 4.33Å; K216-Y239 HydrophobicContact CD-CE2 4.35Å; K216-Y239 HydrophobicContact CG-CE2 4.09Å
217R71.8Confident74.5Confident238 Ų23888.6 Ų88.690%0.89843%0.43SS*.THydrogen-bonded Turntrans57.841.1-179.4-58.4-178.4178.6-175.4-1.1113.3S213 S214S213-R217 PolarHBondContact O-N 2.82Å; S214-R217 PolarHBondContact O-N 3.03Å
218M66.4Low73.6Confident37 Ų3786 Ų8618%0.18242%0.424CS..  trans-105.2138.7172.8-57.9-179.770.600111.4S213 K216 T220 M232 M236S213-M218 VanDerWaalsContact O-CB 3.32Å; S213-M218 WeakPolarHBondContact O-CB 3.44Å; S213-M218 PolarHBondContact O-N 3.29Å; K216-M218 VanDerWaalsContact C-N 3.32Å; K216-M218 HydrophobicContact CB-CG 4.42Å; K216-M218 PolarHBondContact O-N 3.24Å; M218-T220 PolarHBondContact O-N 3.23Å; M218-M232 HydrophobicContact CE-CB 4.46Å; M218-M232 HydrophobicContact CE-CE 3.51Å; M218-M232 HydrophobicContact CE-CG 3.88Å; M218-M232 HydrophobicContact CE-SD 4.36Å; M218-M232 HydrophobicContact SD-CE 3.73Å; M218-M236 HydrophobicContact CE-CE 3.06Å; M218-M236 HydrophobicContact CE-SD 3.78Å; M218-M236 HydrophobicContact CG-SD 4.18Å; M218-M236 HydrophobicContact SD-CE 3.11Å; M218-M236 WeakPolarHBondContact SD-CE 3.44Å; M218-M236 HydrophobicContact SD-SD 3.34Å
219N62.7Low72.8Confident171 Ų17184.3 Ų84.391%0.91442%0.416SS*.  trans-88.4105.6166.7-71.7-7.7000108.6
220T61.6Low72.2Confident31 Ų3186.2 Ų86.219%0.1943%0.429CS..  trans-88.8141.1158.447.80000108.4S213 M218 M232S213-T220 WeakPolarHBondContact OG-CG2 3.24Å; M218-T220 PolarHBondContact O-N 3.23Å; T220-M232 HydrophobicContact CG2-CE 3.98Å; T220-M232 HydrophobicContact CG2-SD 3.84Å
221G59Low71.7Confident53 Ų5386.2 Ų86.255%0.54643%0.431SS..  trans-62.9172172.700000111.8K223G221-K223 PolarHBondContact O-N 3.11Å
222E54.8Low71.1Confident188 Ų18882.2 Ų82.288%0.87941%0.413SS*.SBendtrans-57.1-32.6-179.1-98.4-178.4161.200114.2
223K58.8Low70.7Confident182 Ų18283 Ų8379%0.79142%0.418SS*.SBendtrans-115121.4172.6-67.7-174.5178.4-176.70108.6G221G221-K223 PolarHBondContact O-N 3.11Å
224T63.2Low70.4Confident18 Ų1889.1 Ų89.111%0.1144%0.444CS..  trans-99.5119173.8-50.20000108.4L209 D228L209-T224 HydrophobicContact CD2-CG2 3.58Å; L209-T224 HydrophobicContact CG-CG2 4.43Å; T224-D228 HydrophobicContact CG2-CB 3.99Å
225T67.9Low70.3Confident68 Ų6893 Ų9342%0.41745%0.452SS..  trans-103166.5-179.265.60000111.4R227 D228 L229T225-R227 PolarHBondContact O-N 3.13Å; T225-R227 VanDerWaalsContact O-N 3.15Å; T225-R227 PolarHBondContact OG1-N 3.34Å; T225-D228 WeakPolarHBondContact CB-OD2 3.49Å; T225-D228 PolarHBondContact N-OD2 3.46Å; T225-D228 WeakPolarHBondContact O-CB 3.48Å; T225-D228 PolarHBondContact O-N 2.97Å; T225-D228 VanDerWaalsContact OG1-CG 3.3Å; T225-D228 PolarHBondContact OG1-N 3.42Å; T225-D228 PolarHBondContact OG1-OD2 3.36Å; T225-L229 PolarHBondContact O-N 2.94Å
226M67.5Low69.8Low51 Ų5190.3 Ų90.325%0.25143%0.431SS..Hα-helixtrans-55.4-29.5171.5-70.6-64.1-81.800113S230 L250 Q251M226-S230 PolarHBondContact O-N 3.45Å; M226-S230 VanDerWaalsContact O-N 3.07Å; M226-S230 PolarHBondContact O-OG 3.08Å; M226-L250 HydrophobicContact SD-CB 3.72Å; M226-L250 HydrophobicContact SD-CD1 3.88Å; M226-L250 HydrophobicContact SD-CG 4.46Å; M226-Q251 HydrophobicContact CE-CB 4.29Å
227R69.8Low69.7Low206 Ų20690.1 Ų90.178%0.77744%0.439SS*.Hα-helixtrans-68.9-40.1174.1-69.2-177-179.2171.31.3111.9T225 L229 S230 Q231T225-R227 PolarHBondContact O-N 3.13Å; T225-R227 VanDerWaalsContact O-N 3.15Å; T225-R227 PolarHBondContact OG1-N 3.34Å; R227-L229 VanDerWaalsContact C-N 3.33Å; R227-S230 PolarHBondContact O-N 2.91Å; R227-Q231 WeakPolarHBondContact O-CG 3.3Å; R227-Q231 PolarHBondContact O-N 3.33Å; R227-Q231 VanDerWaalsContact O-N 3.1Å
228D71.8Confident70.3Confident55 Ų5584.6 Ų84.629%0.29442%0.423SS..Hα-helixtrans-65.6-41.2177.1-57.8-48000110.4T224 T225 S230 Q231 M232T224-D228 HydrophobicContact CG2-CB 3.99Å; T225-D228 WeakPolarHBondContact CB-OD2 3.49Å; T225-D228 PolarHBondContact N-OD2 3.46Å; T225-D228 WeakPolarHBondContact O-CB 3.48Å; T225-D228 PolarHBondContact O-N 2.97Å; T225-D228 VanDerWaalsContact OG1-CG 3.3Å; T225-D228 PolarHBondContact OG1-N 3.42Å; T225-D228 PolarHBondContact OG1-OD2 3.36Å; D228-S230 PolarHBondContact O-N 3.32Å; D228-Q231 WeakPolarHBondContact O-CB 3.45Å; D228-Q231 PolarHBondContact O-N 2.94Å; D228-Q231 VanDerWaalsContact O-N 3.13Å; D228-M232 VanDerWaalsContact O-CG 3.27Å; D228-M232 WeakPolarHBondContact O-CG 3.46Å; D228-M232 PolarHBondContact O-N 2.92Å
229L74.2Confident71.2Confident0 Ų085.7 Ų85.70%043%0.426CS..Hα-helixtrans-61.7-44.5176.5-156.292.3000112.2L209 T225 R227 Q231 M232 L233 L243L209-L229 HydrophobicContact CD1-CD1 3.69Å; L209-L229 HydrophobicContact CD2-CD1 3.44Å; L209-L229 VanDerWaalsContact CD2-CD1 3.44Å; L209-L229 HydrophobicContact CG-CD1 4.22Å; T225-L229 PolarHBondContact O-N 2.94Å; R227-L229 VanDerWaalsContact C-N 3.33Å; L229-Q231 VanDerWaalsContact C-N 3.27Å; L229-Q231 PolarHBondContact O-N 3.41Å; L229-M232 PolarHBondContact O-N 3.38Å; L229-M232 VanDerWaalsContact O-N 3.16Å; L229-L233 HydrophobicContact CD2-CD1 4.5Å; L229-L233 PolarHBondContact O-N 3.05Å; L229-L243 HydrophobicContact CD1-CD2 4.25Å
230S73.6Confident72.3Confident41 Ų4183 Ų8329%0.28741%0.408SS..Hα-helixtrans-59.6-35.5173.9-71.90000112.8M226 R227 D228 K234M226-S230 PolarHBondContact O-N 3.45Å; M226-S230 VanDerWaalsContact O-N 3.07Å; M226-S230 PolarHBondContact O-OG 3.08Å; R227-S230 PolarHBondContact O-N 2.91Å; D228-S230 PolarHBondContact O-N 3.32Å; S230-K234 PolarHBondContact O-N 3.47Å
231Q75.2Confident73.5Confident106 Ų10689.2 Ų89.250%0.49543%0.432SS..Hα-helixtrans-73-39.2174.1-70-176.615.200112.2R227 D228 L229 L233 K234 K235R227-Q231 WeakPolarHBondContact O-CG 3.3Å; R227-Q231 PolarHBondContact O-N 3.33Å; R227-Q231 VanDerWaalsContact O-N 3.1Å; D228-Q231 WeakPolarHBondContact O-CB 3.45Å; D228-Q231 PolarHBondContact O-N 2.94Å; D228-Q231 VanDerWaalsContact O-N 3.13Å; L229-Q231 VanDerWaalsContact C-N 3.27Å; L229-Q231 PolarHBondContact O-N 3.41Å; Q231-L233 VanDerWaalsContact C-N 3.34Å; Q231-K234 PolarHBondContact O-N 3.28Å; Q231-K235 WeakPolarHBondContact O-CG 3.3Å; Q231-K235 PolarHBondContact O-N 3.35Å; Q231-K235 VanDerWaalsContact O-N 3.08Å
232M74.8Confident74.8Confident12 Ų1290.3 Ų90.36%0.05942%0.423CS..Hα-helixtrans-62.9-41.2176.9-69.3172.670.700111.6S213 M218 T220 D228 L229 K234 K235 M236 L243S213-M232 WeakPolarHBondContact OG-CE 3.22Å; M218-M232 HydrophobicContact CE-CB 4.46Å; M218-M232 HydrophobicContact CE-CE 3.51Å; M218-M232 HydrophobicContact CE-CG 3.88Å; M218-M232 HydrophobicContact CE-SD 4.36Å; M218-M232 HydrophobicContact SD-CE 3.73Å; T220-M232 HydrophobicContact CG2-CE 3.98Å; T220-M232 HydrophobicContact CG2-SD 3.84Å; D228-M232 VanDerWaalsContact O-CG 3.27Å; D228-M232 WeakPolarHBondContact O-CG 3.46Å; D228-M232 PolarHBondContact O-N 2.92Å; L229-M232 PolarHBondContact O-N 3.38Å; L229-M232 VanDerWaalsContact O-N 3.16Å; M232-K234 VanDerWaalsContact C-N 3.26Å; M232-K234 PolarHBondContact O-N 3.45Å; M232-K235 PolarHBondContact O-N 3.4Å; M232-K235 VanDerWaalsContact O-N 3.11Å; M232-M236 HydrophobicContact CB-CE 4.13Å; M232-M236 HydrophobicContact CE-CE 4.41Å; M232-M236 PolarHBondContact O-N 3.13Å; M232-L243 HydrophobicContact CB-CD1 3.89Å; M232-L243 HydrophobicContact CE-CD2 3.92Å
233L77.2Confident76.3Confident43 Ų4381.4 Ų81.423%0.22538%0.382CS..Hα-helixtrans-55.8-39173.6-84.6155.5000112.3L229 Q231 Q240 L243L229-L233 HydrophobicContact CD2-CD1 4.5Å; L229-L233 PolarHBondContact O-N 3.05Å; Q231-L233 VanDerWaalsContact C-N 3.34Å; L233-Q240 HydrophobicContact CD2-CB 4.27Å; L233-Q240 HydrophobicContact CD2-CG 3.71Å; L233-L243 HydrophobicContact CD2-CB 3.93Å; L233-L243 HydrophobicContact CG-CB 3.99Å; L233-L243 HydrophobicContact CG-CD1 4.39Å
234K78.3Confident77.7Confident129 Ų12974.2 Ų74.256%0.56136%0.355SS*.Hα-helixtrans-73.1-35.4176.2-68.3177.9-174.8-177.20113M173 S230 Q231 M232M173-K234 HydrophobicContact CE-CD 4.39Å; M173-K234 HydrophobicContact CG-CD 4.43Å; S230-K234 PolarHBondContact O-N 3.47Å; Q231-K234 PolarHBondContact O-N 3.28Å; M232-K234 VanDerWaalsContact C-N 3.26Å; M232-K234 PolarHBondContact O-N 3.45Å
235K79.9Confident79Confident157 Ų15775.8 Ų75.868%0.68336%0.36SS*.Hα-helixtrans-78.6-24.1-176.3-73.1-178.5-178.3177.20113.3Q231 M232Q231-K235 WeakPolarHBondContact O-CG 3.3Å; Q231-K235 PolarHBondContact O-N 3.35Å; Q231-K235 VanDerWaalsContact O-N 3.08Å; M232-K235 PolarHBondContact O-N 3.4Å; M232-K235 VanDerWaalsContact O-N 3.11Å
236M74.1Confident80.1Confident19 Ų1973.9 Ų73.99%0.09435%0.345CS..  trans-139.683.8-179-55.8165.2-69.400112M218 M232 Q238 Y239 L243M218-M236 HydrophobicContact CE-CE 3.06Å; M218-M236 HydrophobicContact CE-SD 3.78Å; M218-M236 HydrophobicContact CG-SD 4.18Å; M218-M236 HydrophobicContact SD-CE 3.11Å; M218-M236 WeakPolarHBondContact SD-CE 3.44Å; M218-M236 HydrophobicContact SD-SD 3.34Å; M232-M236 HydrophobicContact CB-CE 4.13Å; M232-M236 HydrophobicContact CE-CE 4.41Å; M232-M236 PolarHBondContact O-N 3.13Å; M236-Q238 VanDerWaalsContact CA-OE1 3.27Å; M236-Q238 PolarHBondContact O-N 3.26Å; M236-Q238 VanDerWaalsContact O-N 3.15Å; M236-Y239 HydrophobicContact CB-CD2 3.99Å; M236-Y239 HydrophobicContact CG-CD2 4.38Å; M236-Y239 PolarHBondContact O-N 3.03Å; M236-Y239 VanDerWaalsContact O-N 3.15Å; M236-Y239 HydrophobicContact SD-CD2 3.73Å; M236-Y239 HydrophobicContact SD-CE2 4.18Å; M236-L243 HydrophobicContact CE-CD1 4.08Å
237P80.9Confident81.1Confident87 Ų8771.7 Ų71.757%0.56534%0.335SS*.G310 helixtrans-59.5-26.117524.7-33.7000112.4Y239 Q240P237-Y239 PolarHBondContact O-N 2.87Å; P237-Q240 VanDerWaalsContact O-CB 3.22Å; P237-Q240 WeakPolarHBondContact O-CB 3.47Å; P237-Q240 PolarHBondContact O-N 3.15Å
238Q85.3Confident82.2Confident122 Ų12262 Ų6257%0.5730%0.298SS*.G310 helixtrans-66.1-20.2178.571.4-84.621.700114.6M236M236-Q238 VanDerWaalsContact CA-OE1 3.27Å; M236-Q238 PolarHBondContact O-N 3.26Å; M236-Q238 VanDerWaalsContact O-N 3.15Å
239Y85.7Confident83.3Confident60 Ų6059.4 Ų59.424%0.23528%0.284CS..G310 helixtrans-112.918.6177-59.5-53.2000112.2F212 K216 M236 P237 K241 E242 L243F212-Y239 HydrophobicContact CZ-CD1 4.1Å; F212-Y239 HydrophobicContact CZ-CG 4.03Å; K216-Y239 HydrophobicContact CB-CE2 4.27Å; K216-Y239 HydrophobicContact CD-CE1 4.33Å; K216-Y239 HydrophobicContact CD-CE2 4.35Å; K216-Y239 HydrophobicContact CG-CE2 4.09Å; M236-Y239 HydrophobicContact CB-CD2 3.99Å; M236-Y239 HydrophobicContact CG-CD2 4.38Å; M236-Y239 PolarHBondContact O-N 3.03Å; M236-Y239 VanDerWaalsContact O-N 3.15Å; M236-Y239 HydrophobicContact SD-CD2 3.73Å; M236-Y239 HydrophobicContact SD-CE2 4.18Å; P237-Y239 PolarHBondContact O-N 2.87Å; Y239-K241 PolarHBondContact O-N 3.15Å; Y239-E242 PolarHBondContact O-N 2.83Å; Y239-L243 WeakPolarHBondContact O-CB 3.48Å; Y239-L243 WeakPolarHBondContact O-CG 3.29Å; Y239-L243 PolarHBondContact O-N 3.26Å
240Q84.2Confident84.1Confident114 Ų11460.5 Ų60.553%0.53329%0.29SS..Hα-helixtrans-60.3-36.4-176.1-179.1175.27.500112L233 P237 S244L233-Q240 HydrophobicContact CD2-CB 4.27Å; L233-Q240 HydrophobicContact CD2-CG 3.71Å; P237-Q240 VanDerWaalsContact O-CB 3.22Å; P237-Q240 WeakPolarHBondContact O-CB 3.47Å; P237-Q240 PolarHBondContact O-N 3.15Å; Q240-S244 WeakPolarHBondContact O-CB 3.21Å; Q240-S244 PolarHBondContact O-N 3Å
241K86.9Confident85.1Confident162 Ų16260.2 Ų60.270%0.70429%0.285SS*.Hα-helixtrans-65-47.9179.9-172.9-179.5178.8-1760111.3Y239 S244 K245Y239-K241 PolarHBondContact O-N 3.15Å; K241-S244 WeakPolarHBondContact O-CB 3.3Å; K241-S244 PolarHBondContact O-N 2.87Å; K241-K245 PolarHBondContact O-N 3.2Å
242E87Confident86.1Confident77 Ų7755.2 Ų55.236%0.3626%0.261SS..Hα-helixtrans-67.5-48.4-179.9-64.292.3143.200111.5F212 Y239 S244 K245 Y246F212-E242 HydrophobicContact CE2-CB 4.04Å; F212-E242 HydrophobicContact CE2-CG 4.21Å; F212-E242 HydrophobicContact CZ-CB 3.86Å; F212-E242 HydrophobicContact CZ-CG 4.34Å; Y239-E242 PolarHBondContact O-N 2.83Å; E242-S244 PolarHBondContact O-N 3.35Å; E242-K245 WeakPolarHBondContact O-CB 3.43Å; E242-K245 PolarHBondContact O-N 3Å; E242-Y246 VanDerWaalsContact O-CD2 3.24Å; E242-Y246 WeakPolarHBondContact O-CD2 3.33Å; E242-Y246 PolarHBondContact O-N 3.07Å
243L86Confident87.1Confident0 Ų054.6 Ų54.60%026%0.258CS..Hα-helixtrans-61.8-34.5177.2-68.7173.7000112L209 F212 L229 M232 L233 M236 Y239 K245 Y246 S247L209-L243 HydrophobicContact CD1-CD2 3.91Å; F212-L243 HydrophobicContact CD1-CD2 4.33Å; F212-L243 HydrophobicContact CE1-CD2 4.06Å; F212-L243 HydrophobicContact CE1-CG 4.37Å; L229-L243 HydrophobicContact CD1-CD2 4.25Å; M232-L243 HydrophobicContact CB-CD1 3.89Å; M232-L243 HydrophobicContact CE-CD2 3.92Å; L233-L243 HydrophobicContact CD2-CB 3.93Å; L233-L243 HydrophobicContact CG-CB 3.99Å; L233-L243 HydrophobicContact CG-CD1 4.39Å; M236-L243 HydrophobicContact CE-CD1 4.08Å; Y239-L243 WeakPolarHBondContact O-CB 3.48Å; Y239-L243 WeakPolarHBondContact O-CG 3.29Å; Y239-L243 PolarHBondContact O-N 3.26Å; L243-K245 VanDerWaalsContact C-N 3.28Å; L243-K245 PolarHBondContact O-N 3.3Å; L243-Y246 PolarHBondContact O-N 3.33Å; L243-S247 PolarHBondContact O-N 3.21Å
244S87.6Confident88Confident32 Ų3257.9 Ų57.922%0.22427%0.272CS..Hα-helixtrans-60.8-35.4174.51680000112.7K179 Q240 K241 E242 S247 T248K179-S244 WeakPolarHBondContact CE-OG 3.39Å; K179-S244 PolarHBondContact NZ-O 2.83Å; K179-S244 PolarHBondContact NZ-OG 3.01Å; Q240-S244 WeakPolarHBondContact O-CB 3.21Å; Q240-S244 PolarHBondContact O-N 3Å; K241-S244 WeakPolarHBondContact O-CB 3.3Å; K241-S244 PolarHBondContact O-N 2.87Å; E242-S244 PolarHBondContact O-N 3.35Å; S244-S247 WeakPolarHBondContact O-CB 3.34Å; S244-S247 PolarHBondContact O-N 3.45Å; S244-T248 PolarHBondContact O-N 2.86Å; S244-T248 VanDerWaalsContact O-N 3.16Å; S244-T248 PolarHBondContact O-OG1 3.03Å; S244-T248 VanDerWaalsContact O-OG1 3.1Å
245K91.2Very high88.8Confident51 Ų5153.1 Ų53.122%0.22225%0.253CS..Hα-helixtrans-66.1-49.5175.6-68.5172.4157.9-152.90111.3D186 D187 K241 E242 L243 S247 T248 H249D186-K245 PolarHBondContact O-NZ 3.06Å; D186-K245 VanDerWaalsContact O-NZ 3.1Å; D187-K245 WeakPolarHBondContact OD1-CD 3.48Å; D187-K245 VanDerWaalsContact OD1-CE 3.29Å; D187-K245 WeakPolarHBondContact OD1-CE 3.02Å; D187-K245 IonicContact OD1-NZ 3.51Å; D187-K245 PolarHBondContact OD1-NZ 3.1Å; K241-K245 PolarHBondContact O-N 3.2Å; E242-K245 WeakPolarHBondContact O-CB 3.43Å; E242-K245 PolarHBondContact O-N 3Å; L243-K245 VanDerWaalsContact C-N 3.28Å; L243-K245 PolarHBondContact O-N 3.3Å; K245-S247 VanDerWaalsContact C-N 3.26Å; K245-S247 PolarHBondContact O-N 2.74Å; K245-T248 WeakPolarHBondContact O-CB 3.24Å; K245-T248 PolarHBondContact O-N 2.9Å; K245-H249 PolarHBondContact O-CD2 3.03Å; K245-H249 PolarHBondContact O-N 2.71Å; K245-H249 VanDerWaalsContact O-N 3.12Å
246Y91Very high89.7Confident28 Ų2845.7 Ų45.711%0.1122%0.221CC..Hα-helixtrans-56.1-40.9175.4-70.7-76.4000112.4L189 V205 Q208 L209 F212 E242 L243 T248 H249 L250L189-Y246 HydrophobicContact CD1-CE1 4.37Å; L189-Y246 HydrophobicContact CD2-CD1 3.56Å; L189-Y246 HydrophobicContact CD2-CE1 3.81Å; L189-Y246 HydrophobicContact CD2-CG 4.05Å; V205-Y246 HydrophobicContact CG1-CD1 4.05Å; Q208-Y246 HydrophobicContact CB-CE1 3.79Å; Q208-Y246 PolarHBondContact O-OH 3.22Å; L209-Y246 HydrophobicContact CB-CD1 3.73Å; L209-Y246 HydrophobicContact CB-CE1 3.92Å; L209-Y246 HydrophobicContact CB-CG 4.2Å; L209-Y246 HydrophobicContact CD1-CD1 4.23Å; L209-Y246 HydrophobicContact CD1-CD2 3.86Å; L209-Y246 HydrophobicContact CD1-CE2 4.32Å; L209-Y246 HydrophobicContact CD1-CG 3.82Å; L209-Y246 HydrophobicContact CG-CD1 4.5Å; F212-Y246 HydrophobicContact CB-CE2 4.26Å; F212-Y246 HydrophobicContact CD1-CE2 4.47Å; F212-Y246 HydrophobicContact CG-CE2 4.19Å; E242-Y246 VanDerWaalsContact O-CD2 3.24Å; E242-Y246 WeakPolarHBondContact O-CD2 3.33Å; E242-Y246 PolarHBondContact O-N 3.07Å; L243-Y246 PolarHBondContact O-N 3.33Å; Y246-T248 VanDerWaalsContact C-N 3.34Å; Y246-T248 PolarHBondContact O-N 3.31Å; Y246-H249 PolarHBondContact O-N 3.17Å; Y246-L250 WeakPolarHBondContact O-CG 3.25Å; Y246-L250 PolarHBondContact O-N 2.78Å
247S88.7Confident90.7Very high5 Ų547.5 Ų47.54%0.03523%0.23CC..Hα-helixtrans-58-46.6175.5-161.50000112.2L243 S244 K245 Q251L243-S247 PolarHBondContact O-N 3.21Å; S244-S247 WeakPolarHBondContact O-CB 3.34Å; S244-S247 PolarHBondContact O-N 3.45Å; K245-S247 VanDerWaalsContact C-N 3.26Å; K245-S247 PolarHBondContact O-N 2.74Å; S247-Q251 WeakPolarHBondContact O-CB 3.31Å; S247-Q251 PolarHBondContact O-N 2.94Å
248T92.8Very high91.5Very high2 Ų250.5 Ų50.51%0.01223%0.234CC..Hα-helixtrans-61.5-48.5-178.7-61.90000110.8Y166 Y168 V181 S244 K245 Y246 Q251 L252Y166-T248 HydrophobicContact CD1-CG2 4Å; Y166-T248 HydrophobicContact CE1-CG2 4.3Å; Y168-T248 HydrophobicContact CE1-CG2 3.93Å; Y168-T248 WeakPolarHBondContact OH-CA 3.43Å; Y168-T248 PolarHBondContact OH-N 3.04Å; Y168-T248 PolarHBondContact OH-OG1 2.78Å; V181-T248 HydrophobicContact CB-CG2 4.08Å; V181-T248 HydrophobicContact CG1-CG2 3.95Å; V181-T248 HydrophobicContact CG2-CG2 4.16Å; S244-T248 PolarHBondContact O-N 2.86Å; S244-T248 VanDerWaalsContact O-N 3.16Å; S244-T248 PolarHBondContact O-OG1 3.03Å; S244-T248 VanDerWaalsContact O-OG1 3.1Å; K245-T248 WeakPolarHBondContact O-CB 3.24Å; K245-T248 PolarHBondContact O-N 2.9Å; Y246-T248 VanDerWaalsContact C-N 3.34Å; Y246-T248 PolarHBondContact O-N 3.31Å; T248-Q251 PolarHBondContact O-N 2.98Å; T248-L252 VanDerWaalsContact O-CB 3.29Å; T248-L252 WeakPolarHBondContact O-CB 3.44Å; T248-L252 PolarHBondContact O-N 2.8Å
249H94.8Very high92Very high0 Ų049.1 Ų49.10%023%0.227CC..Hα-helixtrans-72.3-31-175.9-66.3-62.3000113.2F151 D187 L189 W190 L193 V205 K245 Y246 A253F151-H249 AromaticContact CE1-ND1 3.72Å; F151-H249 HydrophobicContact CZ-CB 4.47Å; D187-H249 IonicContact OD2-CD2 3.42Å; D187-H249 IonicContact OD2-CE1 3.32Å; D187-H249 IonicContact OD2-NE2 3.7Å; D187-H249 PolarHBondContact OD2-NE2 2.96Å; L189-H249 HydrophobicContact CD2-CB 4.34Å; L189-H249 VanDerWaalsContact CD2-CD2 3.43Å; L189-H249 WeakPolarHBondContact CD2-CD2 3.37Å; W190-H249 AromaticContact CE3-CE1 3.76Å; L193-H249 HydrophobicContact CD1-CB 4.05Å; V205-H249 HydrophobicContact CG1-CB 4.44Å; V205-H249 HydrophobicContact CG2-CB 4.05Å; K245-H249 PolarHBondContact O-CD2 3.03Å; K245-H249 PolarHBondContact O-N 2.71Å; K245-H249 VanDerWaalsContact O-N 3.12Å; Y246-H249 PolarHBondContact O-N 3.17Å; H249-A253 WeakPolarHBondContact O-CB 3.34Å; H249-A253 PolarHBondContact O-N 2.86Å
250L91.8Very high92.5Very high23 Ų2347.8 Ų47.812%0.1222%0.222CC..Hα-helixtrans-63.8-47.2169.3-75.2176.4000111.4V205 M226 Y246 A253 E254V205-L250 HydrophobicContact CB-CD2 4Å; V205-L250 HydrophobicContact CB-CG 4.5Å; V205-L250 HydrophobicContact CG1-CD2 3.66Å; V205-L250 HydrophobicContact CG1-CG 3.63Å; M226-L250 HydrophobicContact SD-CB 3.72Å; M226-L250 HydrophobicContact SD-CD1 3.88Å; M226-L250 HydrophobicContact SD-CG 4.46Å; Y246-L250 WeakPolarHBondContact O-CG 3.25Å; Y246-L250 PolarHBondContact O-N 2.78Å; L250-A253 PolarHBondContact O-N 3.41Å; L250-E254 WeakPolarHBondContact O-CB 3.34Å; L250-E254 PolarHBondContact O-N 2.88Å
251Q93.5Very high92.9Very high36 Ų3648.8 Ų48.817%0.16823%0.227CC..Hα-helixtrans-64.2-44178.6-170.963.95000111.6Y166 Y168 M226 S247 T248 A253 E254 D255Y166-Q251 WeakPolarHBondContact OH-CG 3.38Å; Y168-Q251 HydrophobicContact CD2-CB 4.11Å; Y168-Q251 HydrophobicContact CD2-CG 3.66Å; Y168-Q251 HydrophobicContact CE2-CB 4.26Å; Y168-Q251 HydrophobicContact CE2-CG 4.3Å; Y168-Q251 HydrophobicContact CG-CB 4.42Å; Y168-Q251 HydrophobicContact CG-CG 3.87Å; M226-Q251 HydrophobicContact CE-CB 4.29Å; S247-Q251 WeakPolarHBondContact O-CB 3.31Å; S247-Q251 PolarHBondContact O-N 2.94Å; T248-Q251 PolarHBondContact O-N 2.98Å; Q251-A253 VanDerWaalsContact C-N 3.32Å; Q251-A253 PolarHBondContact O-N 2.75Å; Q251-E254 PolarHBondContact O-N 2.79Å; Q251-E254 VanDerWaalsContact O-N 3.17Å; Q251-D255 PolarHBondContact NE2-OD1 3.44Å; Q251-D255 WeakPolarHBondContact O-CB 3.2Å; Q251-D255 PolarHBondContact O-N 3.16Å
252L96.8Very high93.1Very high0 Ų043.2 Ų43.20%022%0.215CC..Hα-helixtrans-60-43178.2-17861.4000111.4F151 L159 I161 Y166 L183 W190 T248 C256F151-L252 HydrophobicContact CE1-CD2 4.1Å; F151-L252 HydrophobicContact CE2-CB 4.23Å; F151-L252 HydrophobicContact CE2-CD2 3.96Å; F151-L252 HydrophobicContact CE2-CG 3.73Å; F151-L252 HydrophobicContact CZ-CB 3.95Å; F151-L252 HydrophobicContact CZ-CD2 3.55Å; F151-L252 HydrophobicContact CZ-CG 3.7Å; L159-L252 HydrophobicContact CD1-CD1 3.42Å; L159-L252 VanDerWaalsContact CD1-CD1 3.42Å; I161-L252 HydrophobicContact CD1-CD1 4.29Å; Y166-L252 HydrophobicContact CD1-CB 4.35Å; Y166-L252 HydrophobicContact CD1-CD1 4.08Å; Y166-L252 HydrophobicContact CD2-CD1 3.92Å; Y166-L252 HydrophobicContact CE1-CB 3.82Å; Y166-L252 HydrophobicContact CE1-CD1 3.97Å; Y166-L252 HydrophobicContact CE1-CG 4.45Å; Y166-L252 HydrophobicContact CE2-CD1 3.84Å; Y166-L252 HydrophobicContact CG-CD1 4.05Å; L183-L252 HydrophobicContact CD1-CD2 4.2Å; L183-L252 HydrophobicContact CD2-CD2 4.22Å; W190-L252 HydrophobicContact CZ3-CD2 3.87Å; T248-L252 VanDerWaalsContact O-CB 3.29Å; T248-L252 WeakPolarHBondContact O-CB 3.44Å; T248-L252 PolarHBondContact O-N 2.8Å; L252-C256 WeakPolarHBondContact O-CB 3.34Å; L252-C256 PolarHBondContact O-N 2.89Å; L252-C256 PolarHBondContact O-SG 2.7Å
253A96.3Very high93.4Very high0 Ų041.5 Ų41.50%021%0.21CC..Hα-helixtrans-66.8-39175.400000112.6F151 I198 V201 H249 L250 Q251 C256 M257F151-A253 HydrophobicContact CE2-CB 4.01Å; F151-A253 HydrophobicContact CZ-CB 4.4Å; I198-A253 HydrophobicContact CD1-CB 4.21Å; V201-A253 HydrophobicContact CG1-CB 4Å; H249-A253 WeakPolarHBondContact O-CB 3.34Å; H249-A253 PolarHBondContact O-N 2.86Å; L250-A253 PolarHBondContact O-N 3.41Å; Q251-A253 VanDerWaalsContact C-N 3.32Å; Q251-A253 PolarHBondContact O-N 2.75Å; A253-C256 PolarHBondContact O-N 3.1Å; A253-M257 WeakPolarHBondContact O-CG 3.3Å; A253-M257 PolarHBondContact O-N 3.02Å
254E94.6Very high93.9Very high111 Ų11142.1 Ų42.152%0.51921%0.213SC..Hα-helixtrans-63.6-44.9175.6-174.4171.5-178.400111.6L250 Q251 M257 K258L250-E254 WeakPolarHBondContact O-CB 3.34Å; L250-E254 PolarHBondContact O-N 2.88Å; Q251-E254 PolarHBondContact O-N 2.79Å; Q251-E254 VanDerWaalsContact O-N 3.17Å; E254-M257 PolarHBondContact O-N 2.81Å; E254-K258 WeakPolarHBondContact O-CB 3.46Å; E254-K258 PolarHBondContact O-N 3.07Å
255D96.7Very high94.2Very high30 Ų3042.5 Ų42.516%0.1621%0.213CC..Hα-helixtrans-63.3-44176.8-74.2-1.8000111.2L159 Y166 Q251 M257 K258 H259L159-D255 HydrophobicContact CD1-CB 3.95Å; L159-D255 HydrophobicContact CD2-CB 3.88Å; Y166-D255 PolarHBondContact OH-OD2 3.44Å; Q251-D255 PolarHBondContact NE2-OD1 3.44Å; Q251-D255 WeakPolarHBondContact O-CB 3.2Å; Q251-D255 PolarHBondContact O-N 3.16Å; D255-M257 VanDerWaalsContact C-N 3.33Å; D255-M257 PolarHBondContact O-N 3.42Å; D255-K258 WeakPolarHBondContact O-CB 3.44Å; D255-K258 PolarHBondContact O-N 3.09Å; D255-H259 PolarHBondContact O-CD2 2.77Å; D255-H259 VanDerWaalsContact O-CD2 3.24Å; D255-H259 PolarHBondContact O-N 3.22Å
256C97.8Very high94.4Very high0 Ų045 Ų450%022%0.224CC..Hα-helixtrans-55.2-49173.1-71.30000111.3M154 I198 L252 A253 K258 H259 Y260M154-C256 HydrophobicContact CE-CB 3.98Å; M154-C256 WeakPolarHBondContact CE-O 3.41Å; M154-C256 HydrophobicContact CG-CB 4.37Å; M154-C256 HydrophobicContact SD-CB 4Å; I198-C256 HydrophobicContact CD1-CB 3.94Å; I198-C256 HydrophobicContact CG1-CB 4.47Å; L252-C256 WeakPolarHBondContact O-CB 3.34Å; L252-C256 PolarHBondContact O-N 2.89Å; L252-C256 PolarHBondContact O-SG 2.7Å; A253-C256 PolarHBondContact O-N 3.1Å; C256-K258 VanDerWaalsContact C-N 3.33Å; C256-K258 PolarHBondContact O-N 2.74Å; C256-H259 PolarHBondContact O-N 3.35Å; C256-Y260 VanDerWaalsContact O-CB 3.31Å; C256-Y260 WeakPolarHBondContact O-CB 3.41Å; C256-Y260 PolarHBondContact O-N 2.84Å
257M96.2Very high94.8Very high58 Ų5843.7 Ų43.729%0.28622%0.219SC..Hα-helixtrans-66.7-34.3-179.5-72.7-57.2-57.900112.8I198 A253 E254 D255 Y260 Q261I198-M257 HydrophobicContact CG1-CG 4.15Å; I198-M257 HydrophobicContact CG1-SD 3.68Å; I198-M257 HydrophobicContact CG2-SD 4.28Å; A253-M257 WeakPolarHBondContact O-CG 3.3Å; A253-M257 PolarHBondContact O-N 3.02Å; E254-M257 PolarHBondContact O-N 2.81Å; D255-M257 VanDerWaalsContact C-N 3.33Å; D255-M257 PolarHBondContact O-N 3.42Å; M257-Y260 HydrophobicContact CE-CD1 4.11Å; M257-Y260 PolarHBondContact O-N 3.12Å; M257-Q261 VanDerWaalsContact O-CG 3.25Å; M257-Q261 WeakPolarHBondContact O-CG 3.31Å; M257-Q261 PolarHBondContact O-N 3.01Å
258K96.4Very high95.2Very high150 Ų15043.5 Ų43.565%0.65222%0.217SC*.Hα-helixtrans-64.2-42.8175.2-177.5-173.9175.9-170.50111.7E254 D255 C256E254-K258 WeakPolarHBondContact O-CB 3.46Å; E254-K258 PolarHBondContact O-N 3.07Å; D255-K258 WeakPolarHBondContact O-CB 3.44Å; D255-K258 PolarHBondContact O-N 3.09Å; C256-K258 VanDerWaalsContact C-N 3.33Å; C256-K258 PolarHBondContact O-N 2.74Å
259H96.2Very high95.3Very high93 Ų9349 Ų4943%0.43124%0.238SC..Hα-helixtrans-73.7-29.4176.9-78.7-109.7000112.5L158 D255 C256 V264L158-H259 HydrophobicContact CB-CB 4.07Å; L158-H259 HydrophobicContact CD1-CB 4.25Å; L158-H259 PolarHBondContact O-ND1 3.29Å; D255-H259 PolarHBondContact O-CD2 2.77Å; D255-H259 VanDerWaalsContact O-CD2 3.24Å; D255-H259 PolarHBondContact O-N 3.22Å; C256-H259 PolarHBondContact O-N 3.35Å; H259-V264 WeakPolarHBondContact O-CG2 3.35Å
260Y96Very high95.5Very high31 Ų3149.7 Ų49.712%0.12224%0.242CC..Iπ-helixtrans-69.1-43.8176.4176.6-99.6000113.7L149 M154 C256 M257 G262 V264 D265 L377L149-Y260 HydrophobicContact CD1-CE2 4.13Å; L149-Y260 HydrophobicContact CD2-CD2 3.81Å; L149-Y260 HydrophobicContact CD2-CE2 3.69Å; M154-Y260 HydrophobicContact CE-CD2 3.95Å; M154-Y260 HydrophobicContact CE-CG 3.96Å; C256-Y260 VanDerWaalsContact O-CB 3.31Å; C256-Y260 WeakPolarHBondContact O-CB 3.41Å; C256-Y260 PolarHBondContact O-N 2.84Å; M257-Y260 HydrophobicContact CE-CD1 4.11Å; M257-Y260 PolarHBondContact O-N 3.12Å; Y260-G262 PolarHBondContact O-N 3.39Å; Y260-V264 HydrophobicContact CD2-CB 4.36Å; Y260-V264 HydrophobicContact CD2-CG1 3.92Å; Y260-V264 HydrophobicContact CE2-CG1 4.49Å; Y260-D265 HydrophobicContact CE1-CB 3.86Å; Y260-D265 HydrophobicContact CE2-CB 4.24Å; Y260-D265 PolarHBondContact O-N 3.46Å; Y260-D265 VanDerWaalsContact O-N 3.12Å; Y260-D265 PolarHBondContact OH-OD1 2.95Å; Y260-L377 WeakPolarHBondContact OH-CD1 3.05Å
261Q92.9Very high95.8Very high136 Ų13648.6 Ų48.664%0.63624%0.236SC*.Iπ-helixtrans-64.9120.6-174-76.5174.11900111.6M257M257-Q261 VanDerWaalsContact O-CG 3.25Å; M257-Q261 WeakPolarHBondContact O-CG 3.31Å; M257-Q261 PolarHBondContact O-N 3.01Å
262G89.9Confident96Very high44 Ų4447 Ų4745%0.45423%0.229SC..Iπ-helixtrans113.3-89.9175.900000112.4Y260 K266Y260-G262 PolarHBondContact O-N 3.39Å; G262-K266 WeakPolarHBondContact O-CE 3.44Å; G262-K266 WeakPolarHBondContact O-CG 3.38Å
263T93.4Very high95.9Very high41 Ų4148.9 Ų48.925%0.25224%0.239SC..Iπ-helixtrans-81.7-49.4-173.1-55.40000112.1D265 K266 L267 V301T263-D265 PolarHBondContact O-N 3.03Å; T263-K266 WeakPolarHBondContact O-CB 3.07Å; T263-K266 PolarHBondContact O-N 3.02Å; T263-K266 VanDerWaalsContact O-N 3.09Å; T263-L267 HydrophobicContact CG2-CD1 4.13Å; T263-L267 HydrophobicContact CG2-CG 4.42Å; T263-L267 WeakPolarHBondContact O-CG 3.24Å; T263-L267 PolarHBondContact O-N 3.49Å; T263-L267 VanDerWaalsContact O-N 3.08Å; T263-V301 HydrophobicContact CG2-CB 4.43Å; T263-V301 HydrophobicContact CG2-CG2 3.75Å
264V96.4Very high96Very high13 Ų1349.1 Ų49.18%0.07924%0.24CC..Iπ-helixtrans-65.5-37.7-174.91780000112.4H147 L158 H259 Y260 K266 L267 C268H147-V264 HydrophobicContact CB-CG1 4.44Å; L158-V264 HydrophobicContact CD1-CG1 4.41Å; L158-V264 HydrophobicContact CD2-CG1 4.33Å; L158-V264 HydrophobicContact CD2-CG2 3.99Å; H259-V264 WeakPolarHBondContact O-CG2 3.35Å; Y260-V264 HydrophobicContact CD2-CB 4.36Å; Y260-V264 HydrophobicContact CD2-CG1 3.92Å; Y260-V264 HydrophobicContact CE2-CG1 4.49Å; V264-K266 VanDerWaalsContact C-N 3.26Å; V264-K266 PolarHBondContact O-N 3.03Å; V264-L267 WeakPolarHBondContact O-CB 3.21Å; V264-L267 PolarHBondContact O-N 3.29Å; V264-L267 VanDerWaalsContact O-N 3.12Å; V264-C268 PolarHBondContact O-N 3.33Å; V264-C268 PolarHBondContact O-SG 2.98Å
265D95.3Very high96Very high40 Ų4044.7 Ų44.721%0.21422%0.222CC..Hα-helixtrans-54.5-41.7171.9177.461.1000112.4Y260 T263 R269 L377Y260-D265 HydrophobicContact CE1-CB 3.86Å; Y260-D265 HydrophobicContact CE2-CB 4.24Å; Y260-D265 PolarHBondContact O-N 3.46Å; Y260-D265 VanDerWaalsContact O-N 3.12Å; Y260-D265 PolarHBondContact OH-OD1 2.95Å; T263-D265 PolarHBondContact O-N 3.03Å; D265-R269 WeakPolarHBondContact O-CG 3.49Å; D265-R269 PolarHBondContact O-N 3.24Å; D265-R269 IonicContact OD1-NE 3.86Å; D265-R269 IonicContact OD1-NH2 3.4Å; D265-R269 PolarHBondContact OD1-NH2 2.83Å; D265-R269 IonicContact OD2-CZ 3.89Å; D265-R269 IonicContact OD2-NE 3.47Å; D265-R269 PolarHBondContact OD2-NE 3.34Å; D265-R269 IonicContact OD2-NH2 3.34Å; D265-R269 PolarHBondContact OD2-NH2 2.85Å; D265-L377 WeakPolarHBondContact OD1-CD1 2.96Å
266K95.7Very high95.9Very high105 Ų10545.9 Ų45.946%0.45723%0.227SC..Hα-helixtrans-69.5-40.7177.7-63.3173.8-169.2171.20111.4G262 T263 V264 R269 I295G262-K266 WeakPolarHBondContact O-CE 3.44Å; G262-K266 WeakPolarHBondContact O-CG 3.38Å; T263-K266 WeakPolarHBondContact O-CB 3.07Å; T263-K266 PolarHBondContact O-N 3.02Å; T263-K266 VanDerWaalsContact O-N 3.09Å; V264-K266 VanDerWaalsContact C-N 3.26Å; V264-K266 PolarHBondContact O-N 3.03Å; K266-R269 PolarHBondContact O-N 2.83Å; K266-I295 HydrophobicContact CB-CD1 4.38Å
267L97.9Very high95.6Very high0 Ų046.8 Ų46.80%024%0.237CC..Hα-helixtrans-60.5-51.2177.4-66.3172000110.4T263 V264 R269 V270 E271 I295 V301 D305 I309T263-L267 HydrophobicContact CG2-CD1 4.13Å; T263-L267 HydrophobicContact CG2-CG 4.42Å; T263-L267 WeakPolarHBondContact O-CG 3.24Å; T263-L267 PolarHBondContact O-N 3.49Å; T263-L267 VanDerWaalsContact O-N 3.08Å; V264-L267 WeakPolarHBondContact O-CB 3.21Å; V264-L267 PolarHBondContact O-N 3.29Å; V264-L267 VanDerWaalsContact O-N 3.12Å; L267-R269 PolarHBondContact O-N 3.39Å; L267-R269 VanDerWaalsContact O-N 3.13Å; L267-V270 PolarHBondContact O-N 2.66Å; L267-E271 WeakPolarHBondContact O-CB 3.19Å; L267-E271 VanDerWaalsContact O-CG 3.3Å; L267-E271 WeakPolarHBondContact O-CG 3.46Å; L267-E271 PolarHBondContact O-N 3.25Å; L267-I295 HydrophobicContact CD2-CD1 4.28Å; L267-I295 HydrophobicContact CD2-CG2 3.56Å; L267-V301 HydrophobicContact CD2-CG1 4.07Å; L267-D305 HydrophobicContact CD1-CB 3.69Å; L267-D305 HydrophobicContact CD2-CB 4.39Å; L267-I309 HydrophobicContact CD2-CD1 4.24Å; L267-I309 HydrophobicContact CD2-CG1 4.05Å
268C98.1Very high95.4Very high0 Ų045.7 Ų45.70%023%0.234CC..Hα-helixtrans-54.3-37.9-178.6-67.90000112.6V264 Q272 L377V264-C268 PolarHBondContact O-N 3.33Å; V264-C268 PolarHBondContact O-SG 2.98Å; C268-Q272 WeakPolarHBondContact O-CB 3.28Å; C268-Q272 WeakPolarHBondContact O-CG 3.34Å; C268-Q272 PolarHBondContact O-N 3.03Å; C268-L377 HydrophobicContact CB-CB 4.31Å; C268-L377 HydrophobicContact CB-CD1 4.35Å; C268-L377 HydrophobicContact CB-CD2 4.47Å
269R95.6Very high95.2Very high119 Ų11940.7 Ų40.745%0.44921%0.214SC..Hα-helixtrans-58.6-52.5176-70.4169.2-167.1-77.6-6.6111.6D265 K266 L267 D273 L377D265-R269 WeakPolarHBondContact O-CG 3.49Å; D265-R269 PolarHBondContact O-N 3.24Å; D265-R269 IonicContact OD1-NE 3.86Å; D265-R269 IonicContact OD1-NH2 3.4Å; D265-R269 PolarHBondContact OD1-NH2 2.83Å; D265-R269 IonicContact OD2-CZ 3.89Å; D265-R269 IonicContact OD2-NE 3.47Å; D265-R269 PolarHBondContact OD2-NE 3.34Å; D265-R269 IonicContact OD2-NH2 3.34Å; D265-R269 PolarHBondContact OD2-NH2 2.85Å; K266-R269 PolarHBondContact O-N 2.83Å; L267-R269 PolarHBondContact O-N 3.39Å; L267-R269 VanDerWaalsContact O-N 3.13Å; R269-D273 PolarHBondContact O-N 3.3Å; R269-L377 HydrophobicContact CB-CD2 4.25Å; R269-L377 HydrophobicContact CG-CD2 3.49Å; R269-L377 VanDerWaalsContact CG-CD2 3.49Å
270V97.6Very high94.9Very high14 Ų1438.3 Ų38.39%0.08521%0.21CC..Hα-helixtrans-68.1-42.1-178.9-176.80000110.5L267 Q272 D273 L274 A291 I292 I295 I309L267-V270 PolarHBondContact O-N 2.66Å; V270-Q272 PolarHBondContact O-N 3.34Å; V270-D273 PolarHBondContact O-N 2.82Å; V270-L274 HydrophobicContact CG1-CD1 3.89Å; V270-L274 HydrophobicContact CG1-CG 4.25Å; V270-L274 VanDerWaalsContact O-CG 3.24Å; V270-L274 WeakPolarHBondContact O-CG 3.5Å; V270-L274 PolarHBondContact O-N 3.06Å; V270-A291 HydrophobicContact CG1-CB 4.18Å; V270-A291 HydrophobicContact CG2-CB 4.19Å; V270-I292 HydrophobicContact CG1-CG1 4.11Å; V270-I295 HydrophobicContact CG2-CG1 4.23Å; V270-I309 HydrophobicContact CB-CD1 4.16Å; V270-I309 HydrophobicContact CG1-CD1 4.08Å
271E98.4Very high94.5Very high0 Ų043.6 Ų43.60%024%0.236CC..Hα-helixtrans-58.4-46.8179-74.1-174.5-178.400112.7L146 H147 L267 L274 A275 I309 L312L146-E271 HydrophobicContact CD2-CB 3.72Å; L146-E271 HydrophobicContact CD2-CG 4.42Å; H147-E271 WeakPolarHBondContact CB-OE2 3.48Å; H147-E271 IonicContact CE1-OE1 3.6Å; H147-E271 IonicContact CG-OE1 3.32Å; H147-E271 IonicContact CG-OE2 2.72Å; H147-E271 PolarHBondContact N-OE2 2.98Å; H147-E271 IonicContact ND1-OE1 2.81Å; H147-E271 PolarHBondContact ND1-OE1 3.46Å; H147-E271 IonicContact ND1-OE2 3.25Å; H147-E271 PolarHBondContact ND1-OE2 2.72Å; L267-E271 WeakPolarHBondContact O-CB 3.19Å; L267-E271 VanDerWaalsContact O-CG 3.3Å; L267-E271 WeakPolarHBondContact O-CG 3.46Å; L267-E271 PolarHBondContact O-N 3.25Å; E271-L274 PolarHBondContact O-N 3.25Å; E271-A275 VanDerWaalsContact O-CB 3.31Å; E271-A275 WeakPolarHBondContact O-CB 3.23Å; E271-A275 PolarHBondContact O-N 3.17Å; E271-I309 HydrophobicContact CG-CD1 3.52Å; E271-L312 HydrophobicContact CB-CD1 3.89Å; E271-L312 HydrophobicContact CG-CD1 3.6Å
272Q97Very high94.3Very high3 Ų339.3 Ų39.31%0.01423%0.229CC..Hα-helixtrans-65.9-40.1179.8-66.2-68.3-4500111.3C268 V270 L274 A275 M276 L377 R379C268-Q272 WeakPolarHBondContact O-CB 3.28Å; C268-Q272 WeakPolarHBondContact O-CG 3.34Å; C268-Q272 PolarHBondContact O-N 3.03Å; V270-Q272 PolarHBondContact O-N 3.34Å; Q272-L274 VanDerWaalsContact C-N 3.31Å; Q272-L274 PolarHBondContact O-N 2.83Å; Q272-A275 PolarHBondContact O-N 3.16Å; Q272-M276 WeakPolarHBondContact O-CB 3.35Å; Q272-M276 WeakPolarHBondContact O-CG 3.47Å; Q272-M276 PolarHBondContact O-N 2.88Å; Q272-L377 WeakPolarHBondContact CG-O 3.45Å; Q272-L377 PolarHBondContact NE2-O 3.35Å; Q272-R379 VanDerWaalsContact CB-NH2 3.31Å
273D96.1Very high94.3Very high39 Ų3943.2 Ų43.221%0.20924%0.235CC..Hα-helixtrans-61.7-40174.3-72.1-7.1000112R269 V270 G277 D279 I285 R379R269-D273 PolarHBondContact O-N 3.3Å; V270-D273 PolarHBondContact O-N 2.82Å; D273-G277 VanDerWaalsContact O-CA 3.28Å; D273-G277 WeakPolarHBondContact O-CA 3.31Å; D273-G277 PolarHBondContact O-N 3.11Å; D273-D279 WeakPolarHBondContact OD1-CA 3.2Å; D273-I285 HydrophobicContact CB-CD1 3.77Å; D273-I285 HydrophobicContact CB-CG1 4.05Å; D273-R379 IonicContact OD1-CZ 3.68Å; D273-R379 IonicContact OD1-NH1 3.76Å; D273-R379 IonicContact OD1-NH2 2.7Å; D273-R379 PolarHBondContact OD1-NH2 3.2Å
274L97.3Very high94.3Very high5 Ų549.1 Ų49.13%0.02626%0.257CS..Hα-helixtrans-71.5-41.9178.3-66175.2000112.7V270 E271 Q272 P288 I292 I309 L312 Y313 L316V270-L274 HydrophobicContact CG1-CD1 3.89Å; V270-L274 HydrophobicContact CG1-CG 4.25Å; V270-L274 VanDerWaalsContact O-CG 3.24Å; V270-L274 WeakPolarHBondContact O-CG 3.5Å; V270-L274 PolarHBondContact O-N 3.06Å; E271-L274 PolarHBondContact O-N 3.25Å; Q272-L274 VanDerWaalsContact C-N 3.31Å; Q272-L274 PolarHBondContact O-N 2.83Å; L274-P288 HydrophobicContact CD2-CB 3.87Å; L274-I292 HydrophobicContact CD1-CD1 3.94Å; L274-I292 HydrophobicContact CD1-CG1 4.07Å; L274-I292 HydrophobicContact CD2-CD1 3.8Å; L274-I292 HydrophobicContact CD2-CG1 4.47Å; L274-I292 HydrophobicContact CG-CD1 4.48Å; L274-I309 HydrophobicContact CD1-CG2 4.23Å; L274-L312 HydrophobicContact CB-CB 3.95Å; L274-L312 HydrophobicContact CD1-CB 4.01Å; L274-Y313 HydrophobicContact CD2-CD2 4.37Å; L274-L316 HydrophobicContact CD2-CD2 3.79Å
275A95.9Very high94.1Very high17 Ų1750.6 Ų50.614%0.1426%0.264CS..Hα-helixtrans-67.7-44.2178.700000111.8V142 L146 E271 Q272 W380V142-A275 HydrophobicContact CG1-CB 3.76Å; L146-A275 HydrophobicContact CD1-CB 4.1Å; L146-A275 HydrophobicContact CD2-CB 4.09Å; E271-A275 VanDerWaalsContact O-CB 3.31Å; E271-A275 WeakPolarHBondContact O-CB 3.23Å; E271-A275 PolarHBondContact O-N 3.17Å; Q272-A275 PolarHBondContact O-N 3.16Å; A275-W380 HydrophobicContact CB-CB 4.49Å; A275-W380 HydrophobicContact CB-CD2 4.17Å; A275-W380 HydrophobicContact CB-CE3 3.74Å; A275-W380 HydrophobicContact CB-CZ3 4.29Å; A275-W380 WeakPolarHBondContact O-CZ3 3.16Å
276M93.2Very high93.8Very high55 Ų5558 Ų5827%0.27129%0.294SS..Hα-helixtrans-80.8-27.4-178.3-61-58.4-70.800112.8Q272 T278 V370 R379 W380Q272-M276 WeakPolarHBondContact O-CB 3.35Å; Q272-M276 WeakPolarHBondContact O-CG 3.47Å; Q272-M276 PolarHBondContact O-N 2.88Å; M276-T278 PolarHBondContact O-N 3.24Å; M276-V370 HydrophobicContact CE-CG2 4.06Å; M276-R379 HydrophobicContact CE-CB 4.2Å; M276-R379 HydrophobicContact CG-CB 3.98Å; M276-R379 HydrophobicContact SD-CB 4.16Å; M276-W380 HydrophobicContact SD-CB 4.25Å; M276-W380 HydrophobicContact SD-CE3 4.01Å
277G92.7Very high93.7Very high19 Ų1956.2 Ų56.220%0.19629%0.29CS..SBendtrans68.87-170.100000114D273 I285D273-G277 VanDerWaalsContact O-CA 3.28Å; D273-G277 WeakPolarHBondContact O-CA 3.31Å; D273-G277 PolarHBondContact O-N 3.11Å; G277-I285 PolarHBondContact O-N 3.03Å
278T92.3Very high93.5Very high36 Ų3656.5 Ų56.522%0.22129%0.292CS..BIsolated β-bridgetrans-138.6152.6178.746.20000109.9M276 G282 E283 K284 R379M276-T278 PolarHBondContact O-N 3.24Å; T278-G282 WeakPolarHBondContact CG2-O 3.47Å; T278-E283 CarbonylContact C-O 3.44Å; T278-E283 WeakPolarHBondContact CA-O 3.16Å; T278-E283 WeakPolarHBondContact CB-O 3.45Å; T278-K284 HydrophobicContact CG2-CG 4.23Å; T278-R379 PolarHBondContact O-NH1 3.39Å
279D91.7Very high93.2Very high45 Ų4558.9 Ų58.924%0.24130%0.304CS..  trans-80.1-178.7174.663.719.4000112.1D273 E281 G282 E283 I285 R379D273-D279 WeakPolarHBondContact OD1-CA 3.2Å; D279-E281 PolarHBondContact O-N 2.66Å; D279-E281 PolarHBondContact OD1-N 3.08Å; D279-E281 VanDerWaalsContact OD1-N 3.16Å; D279-G282 PolarHBondContact O-N 3.17Å; D279-G282 PolarHBondContact OD1-N 3.21Å; D279-G282 VanDerWaalsContact OD1-N 3.11Å; D279-E283 PolarHBondContact N-O 3.24Å; D279-E283 WeakPolarHBondContact OD1-CB 3.5Å; D279-E283 PolarHBondContact OD1-N 3.12Å; D279-E283 WeakPolarHBondContact OD2-CB 3.43Å; D279-I285 HydrophobicContact CB-CD1 3.83Å; D279-R379 PolarHBondContact O-NH1 2.74Å
280A89.4Confident93.1Very high43 Ų4362.7 Ų62.736%0.35532%0.318SS..THydrogen-bonded Turntrans-63.3-22.3-174.600000112.5Q376A280-Q376 HydrophobicContact CB-CG 4.37Å
281E88.4Confident93Very high142 Ų14264 Ų6466%0.66433%0.33SS*.THydrogen-bonded Turntrans-88.7-5.3176.9-63.669.7-152.500112.7D279D279-E281 PolarHBondContact O-N 2.66Å; D279-E281 PolarHBondContact OD1-N 3.08Å; D279-E281 VanDerWaalsContact OD1-N 3.16Å
282G87.6Confident92.9Very high46 Ų4664 Ų6447%0.47433%0.33SS..SBendtrans87.76.7-18000000114.1T278 D279T278-G282 WeakPolarHBondContact CG2-O 3.47Å; D279-G282 PolarHBondContact O-N 3.17Å; D279-G282 PolarHBondContact OD1-N 3.21Å; D279-G282 VanDerWaalsContact OD1-N 3.11Å
283E91Very high92.8Very high125 Ų12566.2 Ų66.258%0.58434%0.344SS*.  trans-79.5139.5178.2-69.5-66.7138.700110.8T278 D279 I285T278-E283 CarbonylContact C-O 3.44Å; T278-E283 WeakPolarHBondContact CA-O 3.16Å; T278-E283 WeakPolarHBondContact CB-O 3.45Å; D279-E283 PolarHBondContact N-O 3.24Å; D279-E283 WeakPolarHBondContact OD1-CB 3.5Å; D279-E283 PolarHBondContact OD1-N 3.12Å; D279-E283 WeakPolarHBondContact OD2-CB 3.43Å; E283-I285 PolarHBondContact O-N 3.17Å
284K92.6Very high92.8Very high165 Ų16568 Ų6872%0.71736%0.358SS*.BIsolated β-bridgetrans-64.4134.9-178.7-71.7-175179179.20111.5T278 K286T278-K284 HydrophobicContact CG2-CG 4.23Å; K284-K286 PolarHBondContact O-N 3.25Å; K284-K286 VanDerWaalsContact O-N 3.1Å
285I92.8Very high92.8Very high44 Ų4468.4 Ų68.423%0.22636%0.36CS..  trans-67.6111.4176-53.1-58000110.2D273 G277 D279 E283 P288D273-I285 HydrophobicContact CB-CD1 3.77Å; D273-I285 HydrophobicContact CB-CG1 4.05Å; G277-I285 PolarHBondContact O-N 3.03Å; D279-I285 HydrophobicContact CB-CD1 3.83Å; E283-I285 PolarHBondContact O-N 3.17Å; I285-P288 HydrophobicContact CG2-CB 4.15Å; I285-P288 HydrophobicContact CG2-CG 3.75Å
286K89.4Confident92.9Very high195 Ų19567.6 Ų67.685%0.84835%0.353SS*.SBendtrans-78.9-44.6-176.1-65177.9-175.71690113.1K284K284-K286 PolarHBondContact O-N 3.25Å; K284-K286 VanDerWaalsContact O-N 3.1Å
287D92.1Very high93Very high69 Ų6970.2 Ų70.237%0.36937%0.367SS..  trans-135.782.5-177-172.6-0.3000111M289 R290D287-M289 PolarHBondContact O-N 2.91Å; D287-M289 PolarHBondContact OD1-N 2.87Å; D287-R290 HydrophobicContact CB-CG 4.35Å; D287-R290 PolarHBondContact O-N 3.05Å; D287-R290 VanDerWaalsContact OD2-CD 3.31Å; D287-R290 WeakPolarHBondContact OD2-CD 3.4Å; D287-R290 VanDerWaalsContact OD2-CG 3.27Å; D287-R290 WeakPolarHBondContact OD2-CG 3.37Å; D287-R290 IonicContact OD2-CZ 3.77Å; D287-R290 IonicContact OD2-NE 2.82Å; D287-R290 PolarHBondContact OD2-NE 2.78Å
288P93.4Very high93.2Very high6 Ų671.1 Ų71.14%0.03937%0.368CS..THydrogen-bonded Turntrans-59.4-26.6-179.4-20.729.7000113.4L274 I285 R290 A291 I292 Y313 L316L274-P288 HydrophobicContact CD2-CB 3.87Å; I285-P288 HydrophobicContact CG2-CB 4.15Å; I285-P288 HydrophobicContact CG2-CG 3.75Å; P288-R290 VanDerWaalsContact C-N 3.29Å; P288-R290 PolarHBondContact O-N 3.39Å; P288-A291 PolarHBondContact O-N 3.25Å; P288-I292 HydrophobicContact CB-CD1 4.19Å; P288-I292 WeakPolarHBondContact O-CD1 3.14Å; P288-I292 WeakPolarHBondContact O-CG1 3.35Å; P288-I292 PolarHBondContact O-N 3.33Å; P288-I292 VanDerWaalsContact O-N 3.14Å; P288-Y313 HydrophobicContact CB-CD2 4.15Å; P288-Y313 HydrophobicContact CB-CE2 4.16Å; P288-L316 HydrophobicContact CB-CD2 4.44Å; P288-L316 HydrophobicContact CG-CD2 3.97Å
289M93.3Very high93.4Very high50 Ų5073.9 Ų73.925%0.24639%0.394CS..Hα-helixtrans-67.3-30-175.5-65.4-76.676.800112.6D287 A291 I292 V293 Y313 L328D287-M289 PolarHBondContact O-N 2.91Å; D287-M289 PolarHBondContact OD1-N 2.87Å; M289-A291 PolarHBondContact O-N 3Å; M289-I292 HydrophobicContact CE-CB 3.84Å; M289-I292 HydrophobicContact CE-CD1 3.23Å; M289-I292 HydrophobicContact CE-CG1 4.11Å; M289-I292 HydrophobicContact CE-CG2 3.94Å; M289-I292 PolarHBondContact O-N 3.17Å; M289-V293 WeakPolarHBondContact O-CB 3.46Å; M289-V293 VanDerWaalsContact O-CG2 3.32Å; M289-V293 WeakPolarHBondContact O-CG2 3.46Å; M289-V293 PolarHBondContact O-N 3.24Å; M289-Y313 HydrophobicContact CE-CD1 3.98Å; M289-Y313 HydrophobicContact CE-CD2 3.64Å; M289-Y313 HydrophobicContact CE-CE1 3.8Å; M289-Y313 HydrophobicContact CE-CE2 3.45Å; M289-Y313 VanDerWaalsContact CE-CE2 3.45Å; M289-Y313 HydrophobicContact CE-CG 3.9Å; M289-Y313 HydrophobicContact SD-CE1 4.22Å; M289-Y313 HydrophobicContact SD-CE2 4.23Å; M289-L328 HydrophobicContact CE-CD2 4.08Å; M289-L328 HydrophobicContact SD-CD2 4.1Å
290R93.9Very high93.5Very high198 Ų19877.9 Ų77.975%0.74742%0.416SS*.Hα-helixtrans-61.4-33.2175.1-74.1177-171.8-156.1-6.1113.1D287 P288 P294D287-R290 HydrophobicContact CB-CG 4.35Å; D287-R290 PolarHBondContact O-N 3.05Å; D287-R290 VanDerWaalsContact OD2-CD 3.31Å; D287-R290 WeakPolarHBondContact OD2-CD 3.4Å; D287-R290 VanDerWaalsContact OD2-CG 3.27Å; D287-R290 WeakPolarHBondContact OD2-CG 3.37Å; D287-R290 IonicContact OD2-CZ 3.77Å; D287-R290 IonicContact OD2-NE 2.82Å; D287-R290 PolarHBondContact OD2-NE 2.78Å; P288-R290 VanDerWaalsContact C-N 3.29Å; P288-R290 PolarHBondContact O-N 3.39Å; R290-P294 WeakPolarHBondContact O-CD 3.35Å; R290-P294 WeakPolarHBondContact O-CG 3.48Å
291A93.7Very high93.9Very high41 Ų4176.2 Ų76.234%0.33940%0.401SS..Hα-helixtrans-83.4-35.6177.700000111.8V270 P288 M289V270-A291 HydrophobicContact CG1-CB 4.18Å; V270-A291 HydrophobicContact CG2-CB 4.19Å; P288-A291 PolarHBondContact O-N 3.25Å; M289-A291 PolarHBondContact O-N 3Å
292I96.1Very high94.3Very high0 Ų071.9 Ų71.90%039%0.387CS..Hα-helixtrans-75.7-47-175.7-69.5163.2000112.5V270 L274 P288 M289 I295 L296 I309 Y313V270-I292 HydrophobicContact CG1-CG1 4.11Å; L274-I292 HydrophobicContact CD1-CD1 3.94Å; L274-I292 HydrophobicContact CD1-CG1 4.07Å; L274-I292 HydrophobicContact CD2-CD1 3.8Å; L274-I292 HydrophobicContact CD2-CG1 4.47Å; L274-I292 HydrophobicContact CG-CD1 4.48Å; P288-I292 HydrophobicContact CB-CD1 4.19Å; P288-I292 WeakPolarHBondContact O-CD1 3.14Å; P288-I292 WeakPolarHBondContact O-CG1 3.35Å; P288-I292 PolarHBondContact O-N 3.33Å; P288-I292 VanDerWaalsContact O-N 3.14Å; M289-I292 HydrophobicContact CE-CB 3.84Å; M289-I292 HydrophobicContact CE-CD1 3.23Å; M289-I292 HydrophobicContact CE-CG1 4.11Å; M289-I292 HydrophobicContact CE-CG2 3.94Å; M289-I292 PolarHBondContact O-N 3.17Å; I292-I295 WeakPolarHBondContact O-CB 3.46Å; I292-I295 PolarHBondContact O-N 3.02Å; I292-L296 HydrophobicContact CG2-CD1 3.65Å; I292-L296 HydrophobicContact CG2-CD2 4.3Å; I292-L296 HydrophobicContact CG2-CG 3.77Å; I292-L296 WeakPolarHBondContact O-CG 3.45Å; I292-L296 PolarHBondContact O-N 3.46Å; I292-I309 HydrophobicContact CB-CG2 4.38Å; I292-I309 HydrophobicContact CG1-CG2 3.92Å; I292-I309 HydrophobicContact CG2-CG2 3.92Å; I292-Y313 HydrophobicContact CD1-CD2 3.47Å; I292-Y313 VanDerWaalsContact CD1-CD2 3.47Å; I292-Y313 HydrophobicContact CD1-CE2 4.32Å; I292-Y313 HydrophobicContact CD1-CG 3.69Å
293V95.6Very high94.8Very high50 Ų5072 Ų7230%0.30338%0.378SS..Hα-helixtrans-55.8-43.8-173.2169.90000113M289 I295 L296 L297M289-V293 WeakPolarHBondContact O-CB 3.46Å; M289-V293 VanDerWaalsContact O-CG2 3.32Å; M289-V293 WeakPolarHBondContact O-CG2 3.46Å; M289-V293 PolarHBondContact O-N 3.24Å; V293-I295 VanDerWaalsContact C-N 3.28Å; V293-I295 PolarHBondContact O-N 3.06Å; V293-L296 PolarHBondContact O-N 3.46Å; V293-L297 HydrophobicContact CG1-CD1 3.69Å; V293-L297 HydrophobicContact CG1-CG 4.23Å; V293-L297 WeakPolarHBondContact O-CG 3.45Å; V293-L297 PolarHBondContact O-N 2.91Å
294P96.8Very high95.2Very high78 Ų7868.2 Ų68.251%0.50636%0.359SS..Hα-helixtrans-57.8-37.4175-26.235.7000113.9R290 D298R290-P294 WeakPolarHBondContact O-CD 3.35Å; R290-P294 WeakPolarHBondContact O-CG 3.48Å; P294-D298 PolarHBondContact O-N 3.19Å
295I97.2Very high95.5Very high13 Ų1361.5 Ų61.57%0.06733%0.331CS..Hα-helixtrans-68.1-43177.1-61.9-62.7000110.8K266 L267 V270 I292 V293 L297 D298 V301 I309K266-I295 HydrophobicContact CB-CD1 4.38Å; L267-I295 HydrophobicContact CD2-CD1 4.28Å; L267-I295 HydrophobicContact CD2-CG2 3.56Å; V270-I295 HydrophobicContact CG2-CG1 4.23Å; I292-I295 WeakPolarHBondContact O-CB 3.46Å; I292-I295 PolarHBondContact O-N 3.02Å; V293-I295 VanDerWaalsContact C-N 3.28Å; V293-I295 PolarHBondContact O-N 3.06Å; I295-L297 VanDerWaalsContact C-N 3.3Å; I295-L297 PolarHBondContact O-N 3.33Å; I295-D298 PolarHBondContact O-N 3.13Å; I295-V301 HydrophobicContact CG2-CG1 4.04Å; I295-V301 HydrophobicContact CG2-CG2 4.21Å; I295-I309 HydrophobicContact CG2-CG1 4.19Å
296L96.9Very high95.8Very high0 Ų060.1 Ų60.10%032%0.323CS..Hα-helixtrans-65.6-34.2-179.6-59.4-172.6000112.4I292 V293 K306 I310 L328 A332I292-L296 HydrophobicContact CG2-CD1 3.65Å; I292-L296 HydrophobicContact CG2-CD2 4.3Å; I292-L296 HydrophobicContact CG2-CG 3.77Å; I292-L296 WeakPolarHBondContact O-CG 3.45Å; I292-L296 PolarHBondContact O-N 3.46Å; V293-L296 PolarHBondContact O-N 3.46Å; L296-K306 HydrophobicContact CD2-CB 3.98Å; L296-K306 HydrophobicContact CD2-CG 4.19Å; L296-K306 VanDerWaalsContact O-CE 3.32Å; L296-K306 WeakPolarHBondContact O-CE 3.26Å; L296-K306 PolarHBondContact O-NZ 3.07Å; L296-I310 HydrophobicContact CD1-CD1 4.45Å; L296-I310 HydrophobicContact CD1-CG1 4.33Å; L296-I310 HydrophobicContact CD2-CD1 4.06Å; L296-I310 HydrophobicContact CD2-CG1 3.95Å; L296-L328 HydrophobicContact CD1-CB 4.46Å; L296-L328 HydrophobicContact CD1-CD2 3.74Å; L296-A332 HydrophobicContact CB-CB 4.07Å; L296-A332 HydrophobicContact CD1-CB 4.41Å; L296-A332 HydrophobicContact CD2-CB 4.04Å; L296-A332 HydrophobicContact CG-CB 4.37Å
297L96.7Very high96.2Very high109 Ų10950.9 Ų50.957%0.57128%0.283SS*.Hα-helixtrans-82-14.8178.8-64.4175000113.8V293 I295 A299V293-L297 HydrophobicContact CG1-CD1 3.69Å; V293-L297 HydrophobicContact CG1-CG 4.23Å; V293-L297 WeakPolarHBondContact O-CG 3.45Å; V293-L297 PolarHBondContact O-N 2.91Å; I295-L297 VanDerWaalsContact C-N 3.3Å; I295-L297 PolarHBondContact O-N 3.33Å; L297-A299 PolarHBondContact O-N 3.2Å
298D96.6Very high96.5Very high38 Ų3847.8 Ų47.820%0.20327%0.266CS..  trans-73.6123.8179.6-166.9-17.3000110.2P294 I295 N300 V301 K306P294-D298 PolarHBondContact O-N 3.19Å; I295-D298 PolarHBondContact O-N 3.13Å; D298-N300 VanDerWaalsContact C-N 3.27Å; D298-N300 PolarHBondContact O-N 2.71Å; D298-N300 WeakPolarHBondContact OD1-CB 3.21Å; D298-N300 PolarHBondContact OD1-N 3.13Å; D298-N300 PolarHBondContact OD1-ND2 3.18Å; D298-V301 HydrophobicContact CB-CB 4.5Å; D298-V301 HydrophobicContact CB-CG2 3.77Å; D298-K306 VanDerWaalsContact O-CE 3.22Å; D298-K306 WeakPolarHBondContact O-CE 3.2Å; D298-K306 PolarHBondContact O-NZ 2.63Å
299A95.3Very high96.8Very high95 Ų9547.5 Ų47.579%0.78526%0.264SS*.THydrogen-bonded Turntrans-75.9-14.8178.600000113L297 V301L297-A299 PolarHBondContact O-N 3.2Å; A299-V301 VanDerWaalsContact C-N 3.34Å
300N95.3Very high97Very high129 Ų12945.1 Ų45.169%0.6925%0.253SS*.THydrogen-bonded Turntrans-85.2-9.4177.1-53.7-68000113D298D298-N300 VanDerWaalsContact C-N 3.27Å; D298-N300 PolarHBondContact O-N 2.71Å; D298-N300 WeakPolarHBondContact OD1-CB 3.21Å; D298-N300 PolarHBondContact OD1-N 3.13Å; D298-N300 PolarHBondContact OD1-ND2 3.18Å
301V97.6Very high97.3Very high7 Ų735.7 Ų35.74%0.04222%0.217CC..SBendtrans-88.2129.7176.7-179.80000108.5T263 L267 I295 D298 A299 D305 K306T263-V301 HydrophobicContact CG2-CB 4.43Å; T263-V301 HydrophobicContact CG2-CG2 3.75Å; L267-V301 HydrophobicContact CD2-CG1 4.07Å; I295-V301 HydrophobicContact CG2-CG1 4.04Å; I295-V301 HydrophobicContact CG2-CG2 4.21Å; D298-V301 HydrophobicContact CB-CB 4.5Å; D298-V301 HydrophobicContact CB-CG2 3.77Å; A299-V301 VanDerWaalsContact C-N 3.34Å; V301-D305 HydrophobicContact CG1-CB 3.64Å; V301-K306 HydrophobicContact CB-CG 4.38Å; V301-K306 HydrophobicContact CG1-CG 3.76Å; V301-K306 WeakPolarHBondContact O-CE 3.46Å
302S97.4Very high97.5Very high52 Ų5233.8 Ų33.836%0.36420%0.201SC..  trans-66.2157.9-17980.10000111.9Y304 D305 K306S302-Y304 VanDerWaalsContact C-N 3.27Å; S302-Y304 PolarHBondContact O-N 3.44Å; S302-D305 WeakPolarHBondContact CB-OD2 3.37Å; S302-D305 PolarHBondContact O-N 2.89Å; S302-D305 WeakPolarHBondContact OG-CB 3.2Å; S302-D305 PolarHBondContact OG-N 3.24Å; S302-D305 VanDerWaalsContact OG-N 3.09Å; S302-D305 PolarHBondContact OG-OD2 3.15Å; S302-K306 WeakPolarHBondContact O-CG 3.12Å; S302-K306 PolarHBondContact O-N 3.41Å; S302-K306 VanDerWaalsContact O-N 3.07Å
303T98.2Very high97.6Very high49 Ų4934.9 Ų34.930%0.30121%0.206SC..Hα-helixtrans-56.8-42.9175.4-55.90000111.7K306 I307 I334 D338T303-K306 PolarHBondContact O-N 2.98Å; T303-I307 HydrophobicContact CG2-CD1 4.07Å; T303-I307 WeakPolarHBondContact O-CG1 3.27Å; T303-I307 PolarHBondContact O-N 2.92Å; T303-I334 HydrophobicContact CG2-CB 4.45Å; T303-I334 HydrophobicContact CG2-CG1 4.23Å; T303-I334 HydrophobicContact CG2-CG2 3.91Å; T303-D338 HydrophobicContact CG2-CB 3.97Å
304Y98.4Very high97.7Very high44 Ų4432.5 Ų32.517%0.17319%0.191CC..Hα-helixtrans-67.7-38-178.6-79.520.9000111.5S302 K306 I307 R308 I341 T478 L481 E482S302-Y304 VanDerWaalsContact C-N 3.27Å; S302-Y304 PolarHBondContact O-N 3.44Å; Y304-K306 PolarHBondContact O-N 2.92Å; Y304-I307 HydrophobicContact CD1-CD1 4.44Å; Y304-I307 WeakPolarHBondContact O-CB 3.45Å; Y304-I307 PolarHBondContact O-N 2.81Å; Y304-I307 VanDerWaalsContact O-N 3.16Å; Y304-R308 VanDerWaalsContact O-CG 3.31Å; Y304-R308 WeakPolarHBondContact O-CG 3.4Å; Y304-R308 PolarHBondContact O-N 2.98Å; Y304-I341 HydrophobicContact CE1-CD1 4.14Å; Y304-T478 HydrophobicContact CD2-CG2 4.01Å; Y304-T478 HydrophobicContact CE2-CG2 3.87Å; Y304-L481 HydrophobicContact CD2-CB 4.13Å; Y304-L481 HydrophobicContact CD2-CD1 3.73Å; Y304-L481 HydrophobicContact CE2-CB 4.06Å; Y304-L481 HydrophobicContact CE2-CD1 4.49Å; Y304-L481 HydrophobicContact CG-CD1 3.79Å; Y304-E482 HydrophobicContact CE2-CG 4.13Å
305D98.6Very high97.6Very high24 Ų2429.5 Ų29.513%0.12817%0.17CC..Hα-helixtrans-64.3-39.7174.3-63.7-35.1000112.2H147 L267 V301 S302 I307 R308 I309H147-D305 IonicContact CE1-OD1 3.72Å; H147-D305 PolarHBondContact CE1-OD1 3.05Å; H147-D305 VanDerWaalsContact CE1-OD1 3.26Å; H147-D305 IonicContact NE2-OD1 3.98Å; L267-D305 HydrophobicContact CD1-CB 3.69Å; L267-D305 HydrophobicContact CD2-CB 4.39Å; V301-D305 HydrophobicContact CG1-CB 3.64Å; S302-D305 WeakPolarHBondContact CB-OD2 3.37Å; S302-D305 PolarHBondContact O-N 2.89Å; S302-D305 WeakPolarHBondContact OG-CB 3.2Å; S302-D305 PolarHBondContact OG-N 3.24Å; S302-D305 VanDerWaalsContact OG-N 3.09Å; S302-D305 PolarHBondContact OG-OD2 3.15Å; D305-I307 VanDerWaalsContact C-N 3.31Å; D305-I307 PolarHBondContact O-N 2.81Å; D305-R308 PolarHBondContact O-N 2.83Å; D305-R308 IonicContact OD1-NH1 3.28Å; D305-I309 WeakPolarHBondContact O-CG1 3.44Å; D305-I309 PolarHBondContact O-N 2.82Å; D305-I309 VanDerWaalsContact O-N 3.07Å
306K98.6Very high97.5Very high16 Ų1630.8 Ų30.87%0.0718%0.177CC..Hα-helixtrans-61.8-41.2172.7-66-179.5-170.9-171.40111.3L296 D298 V301 S302 T303 Y304 I309 I310 A332 I334L296-K306 HydrophobicContact CD2-CB 3.98Å; L296-K306 HydrophobicContact CD2-CG 4.19Å; L296-K306 VanDerWaalsContact O-CE 3.32Å; L296-K306 WeakPolarHBondContact O-CE 3.26Å; L296-K306 PolarHBondContact O-NZ 3.07Å; D298-K306 VanDerWaalsContact O-CE 3.22Å; D298-K306 WeakPolarHBondContact O-CE 3.2Å; D298-K306 PolarHBondContact O-NZ 2.63Å; V301-K306 HydrophobicContact CB-CG 4.38Å; V301-K306 HydrophobicContact CG1-CG 3.76Å; V301-K306 WeakPolarHBondContact O-CE 3.46Å; S302-K306 WeakPolarHBondContact O-CG 3.12Å; S302-K306 PolarHBondContact O-N 3.41Å; S302-K306 VanDerWaalsContact O-N 3.07Å; T303-K306 PolarHBondContact O-N 2.98Å; Y304-K306 PolarHBondContact O-N 2.92Å; K306-I309 PolarHBondContact O-N 2.75Å; K306-I310 VanDerWaalsContact O-CG1 3.28Å; K306-I310 WeakPolarHBondContact O-CG1 3.31Å; K306-I310 PolarHBondContact O-N 2.82Å; K306-A332 HydrophobicContact CB-CB 4.39Å; K306-A332 HydrophobicContact CD-CB 4.03Å; K306-A332 PolarHBondContact NZ-O 2.98Å; K306-I334 HydrophobicContact CB-CD1 4.39Å
307I98.8Very high97.3Very high0 Ų034.5 Ų34.50%019%0.193CC..Hα-helixtrans-63.5-44.4176.4-70.2167.7000111.1T303 Y304 D305 I309 I310 L311 I334 D338 I341 I342 L481T303-I307 HydrophobicContact CG2-CD1 4.07Å; T303-I307 WeakPolarHBondContact O-CG1 3.27Å; T303-I307 PolarHBondContact O-N 2.92Å; Y304-I307 HydrophobicContact CD1-CD1 4.44Å; Y304-I307 WeakPolarHBondContact O-CB 3.45Å; Y304-I307 PolarHBondContact O-N 2.81Å; Y304-I307 VanDerWaalsContact O-N 3.16Å; D305-I307 VanDerWaalsContact C-N 3.31Å; D305-I307 PolarHBondContact O-N 2.81Å; I307-I309 VanDerWaalsContact C-N 3.34Å; I307-I309 PolarHBondContact O-N 2.84Å; I307-I310 PolarHBondContact O-N 3.23Å; I307-L311 HydrophobicContact CG2-CD1 3.83Å; I307-L311 HydrophobicContact CG2-CG 4.23Å; I307-L311 WeakPolarHBondContact O-CB 3.44Å; I307-L311 WeakPolarHBondContact O-CG 3.46Å; I307-L311 PolarHBondContact O-N 2.61Å; I307-I334 HydrophobicContact CD1-CG2 4.18Å; I307-I334 HydrophobicContact CG1-CD1 3.89Å; I307-I334 HydrophobicContact CG1-CG2 4.41Å; I307-D338 HydrophobicContact CD1-CB 3.95Å; I307-D338 WeakPolarHBondContact CD1-O 3.37Å; I307-I341 HydrophobicContact CD1-CD1 3.99Å; I307-I341 HydrophobicContact CG2-CG2 4.01Å; I307-I342 HydrophobicContact CG1-CD1 4.42Å; I307-I342 HydrophobicContact CG1-CG1 4.48Å; I307-I342 HydrophobicContact CG2-CG1 3.96Å; I307-L481 HydrophobicContact CG2-CD2 3.86Å
308R98.8Very high97.1Very high5 Ų530.7 Ų30.72%0.01917%0.173CC..Hα-helixtrans-55.6-47.7175.4-68.5163.173.8157.710.7111.2V145 L146 H147 D157 Y304 D305 I310 L311 L312 L481V145-R308 HydrophobicContact CB-CG 4.32Å; V145-R308 PolarHBondContact O-NE 3.28Å; V145-R308 PolarHBondContact O-NH2 3.05Å; L146-R308 PolarHBondContact O-NH2 3.49Å; L146-R308 VanDerWaalsContact O-NH2 3.14Å; H147-R308 PolarHBondContact CD2-NH2 3.48Å; H147-R308 PolarHBondContact CE1-NH1 3Å; H147-R308 VanDerWaalsContact CG-NH2 3.29Å; H147-R308 VanDerWaalsContact N-NH2 3.13Å; H147-R308 PolarHBondContact ND1-NH2 2.97Å; H147-R308 PolarHBondContact NE2-NH1 2.85Å; D157-R308 IonicContact OD1-CZ 2.9Å; D157-R308 IonicContact OD1-NH1 3.54Å; D157-R308 PolarHBondContact OD1-NH1 2.86Å; D157-R308 IonicContact OD1-NH2 3.54Å; D157-R308 IonicContact OD2-CZ 2.66Å; D157-R308 IonicContact OD2-NH1 2.86Å; D157-R308 PolarHBondContact OD2-NH1 2.85Å; D157-R308 IonicContact OD2-NH2 3.98Å; D157-R308 PolarHBondContact OD2-NH2 3.02Å; Y304-R308 VanDerWaalsContact O-CG 3.31Å; Y304-R308 WeakPolarHBondContact O-CG 3.4Å; Y304-R308 PolarHBondContact O-N 2.98Å; D305-R308 PolarHBondContact O-N 2.83Å; D305-R308 IonicContact OD1-NH1 3.28Å; R308-I310 PolarHBondContact O-N 2.94Å; R308-L311 PolarHBondContact O-N 3.07Å; R308-L312 VanDerWaalsContact O-CG 3.31Å; R308-L312 WeakPolarHBondContact O-CG 3.36Å; R308-L312 PolarHBondContact O-N 2.92Å; R308-L481 HydrophobicContact CG-CD1 4.11Å
309I98.6Very high96.9Very high0 Ų028.9 Ų28.90%016%0.164CC..Hα-helixtrans-62.5-44.1177.5-66.3-72.8000112L267 V270 E271 L274 I292 I295 D305 K306 I307 L312 Y313L267-I309 HydrophobicContact CD2-CD1 4.24Å; L267-I309 HydrophobicContact CD2-CG1 4.05Å; V270-I309 HydrophobicContact CB-CD1 4.16Å; V270-I309 HydrophobicContact CG1-CD1 4.08Å; E271-I309 HydrophobicContact CG-CD1 3.52Å; L274-I309 HydrophobicContact CD1-CG2 4.23Å; I292-I309 HydrophobicContact CB-CG2 4.38Å; I292-I309 HydrophobicContact CG1-CG2 3.92Å; I292-I309 HydrophobicContact CG2-CG2 3.92Å; I295-I309 HydrophobicContact CG2-CG1 4.19Å; D305-I309 WeakPolarHBondContact O-CG1 3.44Å; D305-I309 PolarHBondContact O-N 2.82Å; D305-I309 VanDerWaalsContact O-N 3.07Å; K306-I309 PolarHBondContact O-N 2.75Å; I307-I309 VanDerWaalsContact C-N 3.34Å; I307-I309 PolarHBondContact O-N 2.84Å; I309-L312 PolarHBondContact O-N 2.91Å; I309-Y313 PolarHBondContact O-N 3.2Å
310I98.7Very high96.9Very high0 Ų024.7 Ų24.70%013%0.128CC..Hα-helixtrans-63.5-44.4177.7-69.4166.6000110.5L296 K306 I307 R308 Y313 I314 L325 L328 A332 I334 I342L296-I310 HydrophobicContact CD1-CD1 4.45Å; L296-I310 HydrophobicContact CD1-CG1 4.33Å; L296-I310 HydrophobicContact CD2-CD1 4.06Å; L296-I310 HydrophobicContact CD2-CG1 3.95Å; K306-I310 VanDerWaalsContact O-CG1 3.28Å; K306-I310 WeakPolarHBondContact O-CG1 3.31Å; K306-I310 PolarHBondContact O-N 2.82Å; I307-I310 PolarHBondContact O-N 3.23Å; R308-I310 PolarHBondContact O-N 2.94Å; I310-Y313 WeakPolarHBondContact O-CB 3.5Å; I310-Y313 PolarHBondContact O-N 2.95Å; I310-I314 HydrophobicContact CG2-CD1 3.75Å; I310-I314 HydrophobicContact CG2-CG1 4.42Å; I310-I314 VanDerWaalsContact O-CG1 3.24Å; I310-I314 WeakPolarHBondContact O-CG1 3.31Å; I310-I314 PolarHBondContact O-N 3.35Å; I310-L325 HydrophobicContact CG2-CD1 4.28Å; I310-L328 HydrophobicContact CD1-CB 4.26Å; I310-L328 HydrophobicContact CG1-CB 4.37Å; I310-L328 HydrophobicContact CG2-CD1 4.32Å; I310-A332 HydrophobicContact CD1-CB 4.18Å; I310-I334 HydrophobicContact CD1-CD1 3.55Å; I310-I342 HydrophobicContact CB-CD1 4.46Å; I310-I342 HydrophobicContact CD1-CD1 4.36Å; I310-I342 HydrophobicContact CG2-CD1 3.91Å; I310-I342 HydrophobicContact CG2-CG2 4.43Å
311L98.8Very high96.9Very high0 Ų021 Ų210%011%0.11CC..Hα-helixtrans-59.3-49176.6-77172.4000111.5V145 I307 R308 Y313 I314 F315 I342 M345 I352 L481V145-L311 HydrophobicContact CG1-CD1 4.32Å; I307-L311 HydrophobicContact CG2-CD1 3.83Å; I307-L311 HydrophobicContact CG2-CG 4.23Å; I307-L311 WeakPolarHBondContact O-CB 3.44Å; I307-L311 WeakPolarHBondContact O-CG 3.46Å; I307-L311 PolarHBondContact O-N 2.61Å; R308-L311 PolarHBondContact O-N 3.07Å; L311-Y313 VanDerWaalsContact C-N 3.29Å; L311-Y313 PolarHBondContact O-N 2.88Å; L311-I314 WeakPolarHBondContact O-CB 3.21Å; L311-I314 PolarHBondContact O-N 2.84Å; L311-F315 HydrophobicContact CB-CE1 4.46Å; L311-F315 HydrophobicContact CB-CE2 3.87Å; L311-F315 HydrophobicContact CB-CZ 3.77Å; L311-F315 HydrophobicContact CD2-CE1 4.19Å; L311-F315 HydrophobicContact CD2-CZ 3.89Å; L311-F315 HydrophobicContact CG-CZ 4.33Å; L311-F315 WeakPolarHBondContact O-CD1 3.43Å; L311-F315 VanDerWaalsContact O-CD2 3.3Å; L311-F315 WeakPolarHBondContact O-CD2 3.48Å; L311-F315 WeakPolarHBondContact O-CG 3.39Å; L311-F315 PolarHBondContact O-N 3.12Å; L311-I342 HydrophobicContact CD2-CG2 4.13Å; L311-M345 HydrophobicContact CD1-CE 4Å; L311-M345 HydrophobicContact CD2-CB 4.16Å; L311-M345 HydrophobicContact CD2-CE 4.32Å; L311-M345 HydrophobicContact CD2-CG 4.21Å; L311-I352 HydrophobicContact CD2-CD1 4.38Å; L311-L481 HydrophobicContact CD1-CD2 3.98Å
312L98.6Very high96.8Very high1 Ų126.2 Ų26.21%0.00513%0.134CC..Hα-helixtrans-59.5-39.4177.2-71.2167.5000112.3V142 V145 L146 E271 L274 R308 I309 F315 L316V142-L312 HydrophobicContact CB-CD2 4.41Å; V142-L312 HydrophobicContact CG1-CD2 3.77Å; V142-L312 HydrophobicContact CG2-CD2 4.49Å; V145-L312 HydrophobicContact CG2-CD2 3.81Å; V145-L312 HydrophobicContact CG2-CG 3.97Å; L146-L312 HydrophobicContact CD2-CD1 3.76Å; L146-L312 HydrophobicContact CD2-CD2 3.96Å; L146-L312 HydrophobicContact CG-CD2 4.26Å; E271-L312 HydrophobicContact CB-CD1 3.89Å; E271-L312 HydrophobicContact CG-CD1 3.6Å; L274-L312 HydrophobicContact CB-CB 3.95Å; L274-L312 HydrophobicContact CD1-CB 4.01Å; R308-L312 VanDerWaalsContact O-CG 3.31Å; R308-L312 WeakPolarHBondContact O-CG 3.36Å; R308-L312 PolarHBondContact O-N 2.92Å; I309-L312 PolarHBondContact O-N 2.91Å; L312-F315 HydrophobicContact CD2-CD2 4.37Å; L312-F315 PolarHBondContact O-N 3.46Å; L312-L316 WeakPolarHBondContact O-CB 3.45Å; L312-L316 PolarHBondContact O-N 3.16Å
313Y98.1Very high96.7Very high23 Ų2329.7 Ų29.79%0.0914%0.144CC..Hα-helixtrans-62.1-43.8173.4173.4-109.1000112.4L274 P288 M289 I292 I309 I310 L311 F315 L316 K317 I320 L328L274-Y313 HydrophobicContact CD2-CD2 4.37Å; P288-Y313 HydrophobicContact CB-CD2 4.15Å; P288-Y313 HydrophobicContact CB-CE2 4.16Å; M289-Y313 HydrophobicContact CE-CD1 3.98Å; M289-Y313 HydrophobicContact CE-CD2 3.64Å; M289-Y313 HydrophobicContact CE-CE1 3.8Å; M289-Y313 HydrophobicContact CE-CE2 3.45Å; M289-Y313 VanDerWaalsContact CE-CE2 3.45Å; M289-Y313 HydrophobicContact CE-CG 3.9Å; M289-Y313 HydrophobicContact SD-CE1 4.22Å; M289-Y313 HydrophobicContact SD-CE2 4.23Å; I292-Y313 HydrophobicContact CD1-CD2 3.47Å; I292-Y313 VanDerWaalsContact CD1-CD2 3.47Å; I292-Y313 HydrophobicContact CD1-CE2 4.32Å; I292-Y313 HydrophobicContact CD1-CG 3.69Å; I309-Y313 PolarHBondContact O-N 3.2Å; I310-Y313 WeakPolarHBondContact O-CB 3.5Å; I310-Y313 PolarHBondContact O-N 2.95Å; L311-Y313 VanDerWaalsContact C-N 3.29Å; L311-Y313 PolarHBondContact O-N 2.88Å; Y313-F315 VanDerWaalsContact C-N 3.35Å; Y313-L316 WeakPolarHBondContact O-CB 3.33Å; Y313-L316 PolarHBondContact O-N 2.8Å; Y313-K317 HydrophobicContact CD2-CG 4.27Å; Y313-K317 HydrophobicContact CE1-CG 4.31Å; Y313-K317 HydrophobicContact CE2-CD 4.27Å; Y313-K317 VanDerWaalsContact CE2-CE 3.46Å; Y313-K317 HydrophobicContact CE2-CG 3.76Å; Y313-K317 WeakPolarHBondContact O-CG 3.34Å; Y313-K317 PolarHBondContact O-N 3.37Å; Y313-I320 HydrophobicContact CD1-CG2 4.5Å; Y313-I320 HydrophobicContact CE1-CD1 4.46Å; Y313-I320 HydrophobicContact CE1-CG2 3.94Å; Y313-L328 HydrophobicContact CD1-CD1 3.78Å; Y313-L328 HydrophobicContact CE1-CD1 3.89Å
314I97.1Very high96.5Very high0 Ų030.7 Ų30.70%015%0.148CC..Hα-helixtrans-62.9-42.9176.9-68167.9000110.4I310 L311 K317 N318 G319 I320 L325 I342 I352I310-I314 HydrophobicContact CG2-CD1 3.75Å; I310-I314 HydrophobicContact CG2-CG1 4.42Å; I310-I314 VanDerWaalsContact O-CG1 3.24Å; I310-I314 WeakPolarHBondContact O-CG1 3.31Å; I310-I314 PolarHBondContact O-N 3.35Å; L311-I314 WeakPolarHBondContact O-CB 3.21Å; L311-I314 PolarHBondContact O-N 2.84Å; I314-K317 CarbonylContact O-C 3.55Å; I314-K317 PolarHBondContact O-N 3.09Å; I314-N318 PolarHBondContact O-N 2.84Å; I314-G319 PolarHBondContact O-N 3.21Å; I314-I320 HydrophobicContact CD1-CD1 4.07Å; I314-I320 HydrophobicContact CD1-CG1 4.45Å; I314-I320 HydrophobicContact CG1-CD1 3.69Å; I314-I320 HydrophobicContact CG1-CG1 3.98Å; I314-I320 HydrophobicContact CG1-CG2 4.45Å; I314-L325 HydrophobicContact CD1-CD1 4.06Å; I314-I342 HydrophobicContact CD1-CG2 3.58Å; I314-I352 HydrophobicContact CD1-CG2 4.19Å; I314-I352 HydrophobicContact CG2-CB 4.48Å; I314-I352 HydrophobicContact CG2-CD1 3.89Å; I314-I352 HydrophobicContact CG2-CG2 4.37Å
315F95.8Very high96.5Very high14 Ų1428.8 Ų28.86%0.06114%0.141CC..Hα-helixtrans-65-39.8176.5-54.3-24.3000111.7P141 V142 V145 L311 L312 Y313 K317 N318 M345 V350 I352 K363P141-F315 HydrophobicContact CB-CD1 4.49Å; P141-F315 HydrophobicContact CB-CD2 4.32Å; P141-F315 HydrophobicContact CB-CE1 4.04Å; P141-F315 HydrophobicContact CB-CE2 3.83Å; P141-F315 HydrophobicContact CB-CZ 3.67Å; P141-F315 HydrophobicContact CG-CD1 4.18Å; P141-F315 HydrophobicContact CG-CD2 4.22Å; P141-F315 HydrophobicContact CG-CE1 4.21Å; P141-F315 HydrophobicContact CG-CE2 4.23Å; P141-F315 HydrophobicContact CG-CG 4.21Å; P141-F315 HydrophobicContact CG-CZ 4.22Å; P141-F315 WeakPolarHBondContact O-CE2 3.29Å; V142-F315 HydrophobicContact CG2-CB 4.1Å; V142-F315 HydrophobicContact CG2-CD2 3.83Å; V142-F315 HydrophobicContact CG2-CG 4.34Å; V145-F315 HydrophobicContact CG2-CE2 4.09Å; L311-F315 HydrophobicContact CB-CE1 4.46Å; L311-F315 HydrophobicContact CB-CE2 3.87Å; L311-F315 HydrophobicContact CB-CZ 3.77Å; L311-F315 HydrophobicContact CD2-CE1 4.19Å; L311-F315 HydrophobicContact CD2-CZ 3.89Å; L311-F315 HydrophobicContact CG-CZ 4.33Å; L311-F315 WeakPolarHBondContact O-CD1 3.43Å; L311-F315 VanDerWaalsContact O-CD2 3.3Å; L311-F315 WeakPolarHBondContact O-CD2 3.48Å; L311-F315 WeakPolarHBondContact O-CG 3.39Å; L311-F315 PolarHBondContact O-N 3.12Å; L312-F315 HydrophobicContact CD2-CD2 4.37Å; L312-F315 PolarHBondContact O-N 3.46Å; Y313-F315 VanDerWaalsContact C-N 3.35Å; F315-K317 VanDerWaalsContact C-N 3.32Å; F315-K317 PolarHBondContact O-N 2.96Å; F315-N318 PolarHBondContact O-N 3.41Å; F315-M345 HydrophobicContact CE1-CG 4.11Å; F315-M345 HydrophobicContact CZ-CE 4.19Å; F315-M345 HydrophobicContact CZ-CG 4.1Å; F315-M345 HydrophobicContact CZ-SD 4.48Å; F315-V350 HydrophobicContact CD1-CG1 3.82Å; F315-V350 HydrophobicContact CE1-CG1 3.55Å; F315-I352 HydrophobicContact CE1-CD1 3.96Å; F315-K363 VanDerWaalsContact O-CE 3.25Å; F315-K363 WeakPolarHBondContact O-CE 3.34Å; F315-K363 PolarHBondContact O-NZ 2.81Å
316L94.3Very high96.4Very high40 Ų4031.7 Ų31.721%0.20916%0.156CC..Hα-helixtrans-57.9-46.2172.8176.861.4000111L274 P288 L312 Y313 N318 K363L274-L316 HydrophobicContact CD2-CD2 3.79Å; P288-L316 HydrophobicContact CB-CD2 4.44Å; P288-L316 HydrophobicContact CG-CD2 3.97Å; L312-L316 WeakPolarHBondContact O-CB 3.45Å; L312-L316 PolarHBondContact O-N 3.16Å; Y313-L316 WeakPolarHBondContact O-CB 3.33Å; Y313-L316 PolarHBondContact O-N 2.8Å; L316-N318 VanDerWaalsContact C-N 3.33Å; L316-K363 PolarHBondContact O-NZ 3.32Å
317K92.8Very high96.3Very high78 Ų7835.1 Ų35.134%0.33917%0.171SC..Hα-helixtrans-78.9-11.2-179.1-65.9-61.9-177-176.60114.7Y313 I314 F315 I320Y313-K317 HydrophobicContact CD2-CG 4.27Å; Y313-K317 HydrophobicContact CE1-CG 4.31Å; Y313-K317 HydrophobicContact CE2-CD 4.27Å; Y313-K317 VanDerWaalsContact CE2-CE 3.46Å; Y313-K317 HydrophobicContact CE2-CG 3.76Å; Y313-K317 WeakPolarHBondContact O-CG 3.34Å; Y313-K317 PolarHBondContact O-N 3.37Å; I314-K317 CarbonylContact O-C 3.55Å; I314-K317 PolarHBondContact O-N 3.09Å; F315-K317 VanDerWaalsContact C-N 3.32Å; F315-K317 PolarHBondContact O-N 2.96Å; K317-I320 HydrophobicContact CB-CG2 3.86Å; K317-I320 HydrophobicContact CG-CG2 4.18Å
318N92Very high96.2Very high30 Ų3035.5 Ų35.516%0.1617%0.173CC..THydrogen-bonded Turntrans56.151.6-173-161.434.9000111.4I314 F315 L316 P351 R360 G361I314-N318 PolarHBondContact O-N 2.84Å; F315-N318 PolarHBondContact O-N 3.41Å; L316-N318 VanDerWaalsContact C-N 3.33Å; N318-P351 WeakPolarHBondContact OD1-CG 3.44Å; N318-R360 WeakPolarHBondContact ND2-CA 3.48Å; N318-R360 WeakPolarHBondContact ND2-CB 3.36Å; N318-G361 PolarHBondContact ND2-N 2.72Å; N318-G361 PolarHBondContact ND2-O 3.45Å
319G93.6Very high96.2Very high0 Ų036.6 Ų36.60%018%0.179CC..SBendtrans92.3144.5-175.600000114.3I314 P351 I352 T354 R360I314-G319 PolarHBondContact O-N 3.21Å; G319-P351 WeakPolarHBondContact CA-O 3.23Å; G319-P351 PolarHBondContact N-O 3.09Å; G319-I352 VanDerWaalsContact CA-O 3.3Å; G319-I352 WeakPolarHBondContact CA-O 3.31Å; G319-T354 VanDerWaalsContact C-OG1 3.25Å; G319-T354 PolarHBondContact O-OG1 3.01Å; G319-R360 PolarHBondContact O-NH2 3.03Å
320I94.6Very high96Very high6 Ų643.5 Ų43.53%0.03121%0.212CC..BIsolated β-bridgetrans-125.8168.3179.163.9175.2000111Y313 I314 K317 N324 L325 L328 I352 V353 T354Y313-I320 HydrophobicContact CD1-CG2 4.5Å; Y313-I320 HydrophobicContact CE1-CD1 4.46Å; Y313-I320 HydrophobicContact CE1-CG2 3.94Å; I314-I320 HydrophobicContact CD1-CD1 4.07Å; I314-I320 HydrophobicContact CD1-CG1 4.45Å; I314-I320 HydrophobicContact CG1-CD1 3.69Å; I314-I320 HydrophobicContact CG1-CG1 3.98Å; I314-I320 HydrophobicContact CG1-CG2 4.45Å; K317-I320 HydrophobicContact CB-CG2 3.86Å; K317-I320 HydrophobicContact CG-CG2 4.18Å; I320-N324 HydrophobicContact CD1-CB 4.46Å; I320-L325 HydrophobicContact CD1-CB 3.81Å; I320-L325 HydrophobicContact CD1-CD1 4.31Å; I320-L325 HydrophobicContact CG1-CB 4.23Å; I320-L328 HydrophobicContact CD1-CD1 3.89Å; I320-I352 PolarHBondContact N-O 3.28Å; I320-V353 CarbonylContact O-C 3.55Å; I320-V353 VanDerWaalsContact O-CA 3.3Å; I320-V353 WeakPolarHBondContact O-CA 3.32Å; I320-T354 PolarHBondContact O-N 3.07Å
321T95Very high95.8Very high52 Ų5247.9 Ų47.932%0.31923%0.232SC..  trans-74.5153.617458.60000110.8E323 N324 L325T321-E323 VanDerWaalsContact C-N 3.28Å; T321-E323 PolarHBondContact O-N 3.35Å; T321-N324 PolarHBondContact O-N 3.31Å; T321-N324 VanDerWaalsContact O-N 3.11Å; T321-N324 WeakPolarHBondContact OG1-CB 3.5Å; T321-N324 VanDerWaalsContact OG1-CG 3.32Å; T321-N324 PolarHBondContact OG1-N 3.09Å; T321-N324 PolarHBondContact OG1-ND2 3.34Å; T321-N324 VanDerWaalsContact OG1-ND2 3.09Å; T321-L325 PolarHBondContact O-N 3.16Å
322E95.3Very high95.7Very high116 Ų11648 Ų4854%0.54223%0.232SC..Hα-helixtrans-57.5-40.7177.4-169.5175.2-175.800112.1N324 L325 N326 V353E322-N324 VanDerWaalsContact C-N 3.32Å; E322-N324 PolarHBondContact O-N 3.22Å; E322-L325 PolarHBondContact O-N 2.96Å; E322-N326 WeakPolarHBondContact O-CB 3.3Å; E322-N326 PolarHBondContact O-N 2.99Å; E322-N326 PolarHBondContact O-ND2 3.27Å; E322-V353 HydrophobicContact CB-CG1 3.96Å
323E95.7Very high95.6Very high125 Ų12556 Ų5658%0.58427%0.27SS*.Hα-helixtrans-58.1-43175.8-170.6-167.1157.900112.3T321 K327T321-E323 VanDerWaalsContact C-N 3.28Å; T321-E323 PolarHBondContact O-N 3.35Å; E323-K327 WeakPolarHBondContact O-CG 3.47Å; E323-K327 PolarHBondContact O-N 3.41Å; E323-K327 VanDerWaalsContact O-N 3.13Å; E323-K327 WeakPolarHBondContact OE1-CE 3.3Å; E323-K327 IonicContact OE1-NZ 3.53Å; E323-K327 PolarHBondContact OE1-NZ 2.95Å
324N95.6Very high95.6Very high70 Ų7055.6 Ų55.637%0.37427%0.269SS..Hα-helixtrans-71.3-37.1179.7-75-24.3000111.5I320 T321 E322 K327 L328I320-N324 HydrophobicContact CD1-CB 4.46Å; T321-N324 PolarHBondContact O-N 3.31Å; T321-N324 VanDerWaalsContact O-N 3.11Å; T321-N324 WeakPolarHBondContact OG1-CB 3.5Å; T321-N324 VanDerWaalsContact OG1-CG 3.32Å; T321-N324 PolarHBondContact OG1-N 3.09Å; T321-N324 PolarHBondContact OG1-ND2 3.34Å; T321-N324 VanDerWaalsContact OG1-ND2 3.09Å; E322-N324 VanDerWaalsContact C-N 3.32Å; E322-N324 PolarHBondContact O-N 3.22Å; N324-K327 PolarHBondContact O-N 2.9Å; N324-L328 WeakPolarHBondContact O-CG 2.87Å; N324-L328 PolarHBondContact O-N 2.98Å; N324-L328 VanDerWaalsContact O-N 3.13Å
325L96.9Very high95.5Very high4 Ų457.8 Ų57.82%0.02128%0.283CS..Hα-helixtrans-61.4-47.8174.2177.356.3000110.9I310 I314 I320 T321 E322 K327 L328 I329 I342 T343 I352 V353I310-L325 HydrophobicContact CG2-CD1 4.28Å; I314-L325 HydrophobicContact CD1-CD1 4.06Å; I320-L325 HydrophobicContact CD1-CB 3.81Å; I320-L325 HydrophobicContact CD1-CD1 4.31Å; I320-L325 HydrophobicContact CG1-CB 4.23Å; T321-L325 PolarHBondContact O-N 3.16Å; E322-L325 PolarHBondContact O-N 2.96Å; L325-K327 VanDerWaalsContact C-N 3.3Å; L325-K327 PolarHBondContact O-N 3.31Å; L325-L328 WeakPolarHBondContact O-CB 3.28Å; L325-L328 PolarHBondContact O-N 3.34Å; L325-L328 VanDerWaalsContact O-N 3.08Å; L325-I329 HydrophobicContact CD1-CD1 3.88Å; L325-I329 HydrophobicContact CD1-CG1 4.18Å; L325-I329 HydrophobicContact CG-CD1 3.8Å; L325-I329 WeakPolarHBondContact O-CG1 3.43Å; L325-I329 PolarHBondContact O-N 3.43Å; L325-I342 HydrophobicContact CD1-CD1 4.39Å; L325-I342 HydrophobicContact CD1-CG2 3.8Å; L325-I342 HydrophobicContact CD2-CG2 4.42Å; L325-T343 HydrophobicContact CD2-CG2 4.15Å; L325-I352 HydrophobicContact CD2-CG2 4.43Å; L325-V353 HydrophobicContact CD2-CG2 3.77Å
326N96.6Very high95.4Very high85 Ų8562 Ų6246%0.45531%0.312SS..Hα-helixtrans-60.4-38.5179-72.1-22000112.3E322 I329 Q330E322-N326 WeakPolarHBondContact O-CB 3.3Å; E322-N326 PolarHBondContact O-N 2.99Å; E322-N326 PolarHBondContact O-ND2 3.27Å; N326-I329 PolarHBondContact O-N 3.31Å; N326-Q330 VanDerWaalsContact O-CB 3.3Å; N326-Q330 WeakPolarHBondContact O-CB 3.42Å; N326-Q330 PolarHBondContact O-N 2.97Å
327K96.6Very high95.3Very high88 Ų8865.7 Ų65.738%0.38333%0.328SS..Hα-helixtrans-62.8-43173.5-73.5173.7-173.5166.30112.3E323 N324 L325 Q330 H331E323-K327 WeakPolarHBondContact O-CG 3.47Å; E323-K327 PolarHBondContact O-N 3.41Å; E323-K327 VanDerWaalsContact O-N 3.13Å; E323-K327 WeakPolarHBondContact OE1-CE 3.3Å; E323-K327 IonicContact OE1-NZ 3.53Å; E323-K327 PolarHBondContact OE1-NZ 2.95Å; N324-K327 PolarHBondContact O-N 2.9Å; L325-K327 VanDerWaalsContact C-N 3.3Å; L325-K327 PolarHBondContact O-N 3.31Å; K327-Q330 PolarHBondContact O-N 2.99Å; K327-H331 WeakPolarHBondContact O-CB 3.28Å; K327-H331 PolarHBondContact O-CD2 2.88Å; K327-H331 PolarHBondContact O-N 3.27Å
328L97.3Very high95.5Very high9 Ų962.6 Ų62.65%0.04732%0.316CS..Hα-helixtrans-63.3-46.2177.4-69.4169.5000111.4M289 L296 I310 Y313 I320 N324 L325 Q330 H331 A332M289-L328 HydrophobicContact CE-CD2 4.08Å; M289-L328 HydrophobicContact SD-CD2 4.1Å; L296-L328 HydrophobicContact CD1-CB 4.46Å; L296-L328 HydrophobicContact CD1-CD2 3.74Å; I310-L328 HydrophobicContact CD1-CB 4.26Å; I310-L328 HydrophobicContact CG1-CB 4.37Å; I310-L328 HydrophobicContact CG2-CD1 4.32Å; Y313-L328 HydrophobicContact CD1-CD1 3.78Å; Y313-L328 HydrophobicContact CE1-CD1 3.89Å; I320-L328 HydrophobicContact CD1-CD1 3.89Å; N324-L328 WeakPolarHBondContact O-CG 2.87Å; N324-L328 PolarHBondContact O-N 2.98Å; N324-L328 VanDerWaalsContact O-N 3.13Å; L325-L328 WeakPolarHBondContact O-CB 3.28Å; L325-L328 PolarHBondContact O-N 3.34Å; L325-L328 VanDerWaalsContact O-N 3.08Å; L328-Q330 VanDerWaalsContact C-N 3.33Å; L328-Q330 PolarHBondContact O-N 3.07Å; L328-H331 PolarHBondContact O-N 3.33Å; L328-A332 VanDerWaalsContact O-CB 3.24Å; L328-A332 WeakPolarHBondContact O-CB 3.41Å; L328-A332 PolarHBondContact O-N 2.66Å
329I97.5Very high95.6Very high27 Ų2762.3 Ų62.314%0.13832%0.316CS..Hα-helixtrans-59.3-45.3176.7-68.4164.9000110.5L325 N326 A332 Q333 I334 I342L325-I329 HydrophobicContact CD1-CD1 3.88Å; L325-I329 HydrophobicContact CD1-CG1 4.18Å; L325-I329 HydrophobicContact CG-CD1 3.8Å; L325-I329 WeakPolarHBondContact O-CG1 3.43Å; L325-I329 PolarHBondContact O-N 3.43Å; N326-I329 PolarHBondContact O-N 3.31Å; I329-A332 PolarHBondContact O-N 2.88Å; I329-Q333 PolarHBondContact O-N 3.19Å; I329-I334 HydrophobicContact CG2-CB 4.36Å; I329-I334 PolarHBondContact O-N 3.28Å; I329-I342 HydrophobicContact CD1-CD1 4.46Å; I329-I342 HydrophobicContact CG1-CD1 4.13Å
330Q96.1Very high95.7Very high146 Ų14666.2 Ų66.268%0.68233%0.334SS*.Hα-helixtrans-63.1-46178.9-173.5-178.131.600112.2N326 K327 L328 A332 Q333N326-Q330 VanDerWaalsContact O-CB 3.3Å; N326-Q330 WeakPolarHBondContact O-CB 3.42Å; N326-Q330 PolarHBondContact O-N 2.97Å; K327-Q330 PolarHBondContact O-N 2.99Å; L328-Q330 VanDerWaalsContact C-N 3.33Å; L328-Q330 PolarHBondContact O-N 3.07Å; Q330-A332 VanDerWaalsContact C-N 3.3Å; Q330-A332 PolarHBondContact O-N 2.82Å; Q330-Q333 PolarHBondContact O-N 3.24Å
331H93.8Very high95.9Very high91 Ų9166 Ų6642%0.42133%0.333SS..Hα-helixtrans-64.5-35.8177.2-76.3-53000112.5K327 L328 Q333K327-H331 WeakPolarHBondContact O-CB 3.28Å; K327-H331 PolarHBondContact O-CD2 2.88Å; K327-H331 PolarHBondContact O-N 3.27Å; L328-H331 PolarHBondContact O-N 3.33Å; H331-Q333 VanDerWaalsContact C-N 3.28Å; H331-Q333 PolarHBondContact O-N 3.39Å
332A96.5Very high96Very high2 Ų263.5 Ų63.52%0.01732%0.318CS..Hα-helixtrans-76.7-13.7179.100000113.8L296 K306 I310 L328 I329 Q330 I334L296-A332 HydrophobicContact CB-CB 4.07Å; L296-A332 HydrophobicContact CD1-CB 4.41Å; L296-A332 HydrophobicContact CD2-CB 4.04Å; L296-A332 HydrophobicContact CG-CB 4.37Å; K306-A332 HydrophobicContact CB-CB 4.39Å; K306-A332 HydrophobicContact CD-CB 4.03Å; K306-A332 PolarHBondContact NZ-O 2.98Å; I310-A332 HydrophobicContact CD1-CB 4.18Å; L328-A332 VanDerWaalsContact O-CB 3.24Å; L328-A332 WeakPolarHBondContact O-CB 3.41Å; L328-A332 PolarHBondContact O-N 2.66Å; I329-A332 PolarHBondContact O-N 2.88Å; Q330-A332 VanDerWaalsContact C-N 3.3Å; Q330-A332 PolarHBondContact O-N 2.82Å; A332-I334 HydrophobicContact CB-CD1 3.53Å; A332-I334 HydrophobicContact CB-CG1 3.6Å; A332-I334 PolarHBondContact O-N 3.19Å
333Q97Very high96.1Very high171 Ų17160.6 Ų60.680%0.79931%0.308SS*.THydrogen-bonded Turntrans5439.5-174.3-58.7-175-40.200112.8I329 Q330 H331I329-Q333 PolarHBondContact O-N 3.19Å; Q330-Q333 PolarHBondContact O-N 3.24Å; H331-Q333 VanDerWaalsContact C-N 3.28Å; H331-Q333 PolarHBondContact O-N 3.39Å
334I96.9Very high96.2Very high13 Ų1354.8 Ų54.87%0.06728%0.281CS..  trans-75.3132.3-178.6-64.7163.9000109.4T303 K306 I307 I310 I329 A332 D338T303-I334 HydrophobicContact CG2-CB 4.45Å; T303-I334 HydrophobicContact CG2-CG1 4.23Å; T303-I334 HydrophobicContact CG2-CG2 3.91Å; K306-I334 HydrophobicContact CB-CD1 4.39Å; I307-I334 HydrophobicContact CD1-CG2 4.18Å; I307-I334 HydrophobicContact CG1-CD1 3.89Å; I307-I334 HydrophobicContact CG1-CG2 4.41Å; I310-I334 HydrophobicContact CD1-CD1 3.55Å; I329-I334 HydrophobicContact CG2-CB 4.36Å; I329-I334 PolarHBondContact O-N 3.28Å; A332-I334 HydrophobicContact CB-CD1 3.53Å; A332-I334 HydrophobicContact CB-CG1 3.6Å; A332-I334 PolarHBondContact O-N 3.19Å; I334-D338 HydrophobicContact CG2-CB 3.7Å
335P96.4Very high96.2Very high46 Ų4651.6 Ų51.630%0.29926%0.264SS..  trans-56.9146.6173.6-26.236000112.5E337 D338 S339P335-E337 VanDerWaalsContact C-N 3.28Å; P335-E337 HydrophobicContact CB-CG 3.87Å; P335-E337 PolarHBondContact O-N 3.14Å; P335-D338 HydrophobicContact CB-CB 4.49Å; P335-D338 PolarHBondContact O-N 3.37Å; P335-S339 PolarHBondContact O-N 3.37Å
336P93.1Very high96.2Very high103 Ų10353.6 Ų53.667%0.66928%0.281SS*.Hα-helixtrans-53.5-43.8-179.9-2835.5000113.5D338 S339 E340P336-D338 VanDerWaalsContact C-N 3.25Å; P336-D338 PolarHBondContact O-N 3.21Å; P336-S339 PolarHBondContact O-N 3.33Å; P336-S339 VanDerWaalsContact O-N 3.14Å; P336-S339 PolarHBondContact O-OG 2.95Å; P336-E340 PolarHBondContact O-N 3.14Å
337E92.1Very high96.1Very high118 Ų11852.9 Ų52.955%0.55128%0.275SS*.Hα-helixtrans-58.7-30.917759.9-174.1-110.100114.4P335 K485P335-E337 VanDerWaalsContact C-N 3.28Å; P335-E337 HydrophobicContact CB-CG 3.87Å; P335-E337 PolarHBondContact O-N 3.14Å; E337-K485 IonicContact OE1-NZ 3.06Å; E337-K485 PolarHBondContact OE1-NZ 3.16Å
338D96.3Very high96.1Very high13 Ų1348.9 Ų48.97%0.0726%0.258CS..Hα-helixtrans-89.8-27.6178.7-68.6-33.3000110.9T303 I307 I334 P335 P336 E340 I341 K485T303-D338 HydrophobicContact CG2-CB 3.97Å; I307-D338 HydrophobicContact CD1-CB 3.95Å; I307-D338 WeakPolarHBondContact CD1-O 3.37Å; I334-D338 HydrophobicContact CG2-CB 3.7Å; P335-D338 HydrophobicContact CB-CB 4.49Å; P335-D338 PolarHBondContact O-N 3.37Å; P336-D338 VanDerWaalsContact C-N 3.25Å; P336-D338 PolarHBondContact O-N 3.21Å; D338-E340 PolarHBondContact O-N 3Å; D338-I341 HydrophobicContact CB-CD1 4.34Å; D338-I341 WeakPolarHBondContact O-CB 3.38Å; D338-I341 WeakPolarHBondContact O-CD1 3.35Å; D338-I341 VanDerWaalsContact O-CG1 3.29Å; D338-I341 WeakPolarHBondContact O-CG1 3.4Å; D338-I341 PolarHBondContact O-N 2.69Å; D338-I341 VanDerWaalsContact O-N 3.14Å; D338-K485 WeakPolarHBondContact OD1-CD 3.41Å; D338-K485 WeakPolarHBondContact OD1-CE 3.33Å; D338-K485 IonicContact OD1-NZ 3.74Å; D338-K485 PolarHBondContact OD1-NZ 3.36Å
339S95.6Very high95.9Very high24 Ų2451.3 Ų51.317%0.16829%0.285CS..Hα-helixtrans-64.6-29.2177.875.80000112.6P335 P336 I341 I342P335-S339 PolarHBondContact O-N 3.37Å; P336-S339 PolarHBondContact O-N 3.33Å; P336-S339 VanDerWaalsContact O-N 3.14Å; P336-S339 PolarHBondContact O-OG 2.95Å; S339-I341 PolarHBondContact O-N 3.22Å; S339-I342 WeakPolarHBondContact O-CB 3.26Å; S339-I342 PolarHBondContact O-N 3.09Å; S339-I342 VanDerWaalsContact O-N 3.12Å
340E95.3Very high95.7Very high82 Ų8250.4 Ų50.438%0.38328%0.281SS..Hα-helixtrans-61.2-26.5175-70.5-167.8-160.700112.9P336 D338 I342 T343 N344 N488P336-E340 PolarHBondContact O-N 3.14Å; D338-E340 PolarHBondContact O-N 3Å; E340-I342 PolarHBondContact O-N 3.38Å; E340-T343 WeakPolarHBondContact CA-OG1 3.2Å; E340-T343 PolarHBondContact O-N 3.04Å; E340-T343 PolarHBondContact O-OG1 2.69Å; E340-N344 VanDerWaalsContact O-CB 3.26Å; E340-N344 WeakPolarHBondContact O-CB 3.44Å; E340-N344 PolarHBondContact O-N 2.79Å; E340-N344 PolarHBondContact O-ND2 3.26Å; E340-N344 PolarHBondContact O-OD1 3.23Å; E340-N488 PolarHBondContact OE2-ND2 2.91Å; E340-N488 VanDerWaalsContact OE2-ND2 3.12Å
341I98Very high95.6Very high0 Ų045.7 Ų45.70%026%0.262CS..Hα-helixtrans-54.3-40.5175.2-63.7167.9000110.5Y304 I307 D338 S339 M345 L481 L484 K485Y304-I341 HydrophobicContact CE1-CD1 4.14Å; I307-I341 HydrophobicContact CD1-CD1 3.99Å; I307-I341 HydrophobicContact CG2-CG2 4.01Å; D338-I341 HydrophobicContact CB-CD1 4.34Å; D338-I341 WeakPolarHBondContact O-CB 3.38Å; D338-I341 WeakPolarHBondContact O-CD1 3.35Å; D338-I341 VanDerWaalsContact O-CG1 3.29Å; D338-I341 WeakPolarHBondContact O-CG1 3.4Å; D338-I341 PolarHBondContact O-N 2.69Å; D338-I341 VanDerWaalsContact O-N 3.14Å; S339-I341 PolarHBondContact O-N 3.22Å; I341-M345 PolarHBondContact O-N 3.42Å; I341-L481 HydrophobicContact CD1-CB 4.42Å; I341-L481 HydrophobicContact CG2-CB 4.25Å; I341-L481 HydrophobicContact CG2-CD2 3.53Å; I341-L481 HydrophobicContact CG2-CG 4.47Å; I341-L484 HydrophobicContact CB-CB 4.5Å; I341-L484 HydrophobicContact CG2-CB 3.85Å; I341-L484 HydrophobicContact CG2-CD1 4.09Å; I341-K485 HydrophobicContact CD1-CB 3.94Å; I341-K485 HydrophobicContact CD1-CD 4.27Å; I341-K485 HydrophobicContact CD1-CG 4.26Å; I341-K485 HydrophobicContact CG1-CB 3.69Å; I341-K485 HydrophobicContact CG1-CG 4.15Å
342I98.2Very high95.7Very high0 Ų041.5 Ų41.50%024%0.243CC..Hα-helixtrans-66.6-46.7-177.9-59.3162.6000110.4I307 I310 L311 I314 L325 I329 S339 E340 M345 I352I307-I342 HydrophobicContact CG1-CD1 4.42Å; I307-I342 HydrophobicContact CG1-CG1 4.48Å; I307-I342 HydrophobicContact CG2-CG1 3.96Å; I310-I342 HydrophobicContact CB-CD1 4.46Å; I310-I342 HydrophobicContact CD1-CD1 4.36Å; I310-I342 HydrophobicContact CG2-CD1 3.91Å; I310-I342 HydrophobicContact CG2-CG2 4.43Å; L311-I342 HydrophobicContact CD2-CG2 4.13Å; I314-I342 HydrophobicContact CD1-CG2 3.58Å; L325-I342 HydrophobicContact CD1-CD1 4.39Å; L325-I342 HydrophobicContact CD1-CG2 3.8Å; L325-I342 HydrophobicContact CD2-CG2 4.42Å; I329-I342 HydrophobicContact CD1-CD1 4.46Å; I329-I342 HydrophobicContact CG1-CD1 4.13Å; S339-I342 WeakPolarHBondContact O-CB 3.26Å; S339-I342 PolarHBondContact O-N 3.09Å; S339-I342 VanDerWaalsContact O-N 3.12Å; E340-I342 PolarHBondContact O-N 3.38Å; I342-M345 WeakPolarHBondContact O-CB 3.29Å; I342-I352 HydrophobicContact CG2-CG2 3.97Å; I342-I352 WeakPolarHBondContact O-CG2 3.48Å
343T96.4Very high95.6Very high56 Ų5644.3 Ų44.334%0.34426%0.26SS..Hα-helixtrans-71.6-34.5-179.948.70000112.2L325 E340 M345 A346L325-T343 HydrophobicContact CD2-CG2 4.15Å; E340-T343 WeakPolarHBondContact CA-OG1 3.2Å; E340-T343 PolarHBondContact O-N 3.04Å; E340-T343 PolarHBondContact O-OG1 2.69Å; T343-M345 PolarHBondContact O-N 2.91Å; T343-A346 WeakPolarHBondContact O-CB 3.17Å; T343-A346 PolarHBondContact O-N 3.47Å
344N97Very high95.1Very high3 Ų337 Ų372%0.01623%0.227CC..Hα-helixtrans-68.3-22.7-178.4-67.7-4.3000112.5E340 A346 H347 L484 M487 N488E340-N344 VanDerWaalsContact O-CB 3.26Å; E340-N344 WeakPolarHBondContact O-CB 3.44Å; E340-N344 PolarHBondContact O-N 2.79Å; E340-N344 PolarHBondContact O-ND2 3.26Å; E340-N344 PolarHBondContact O-OD1 3.23Å; N344-A346 PolarHBondContact O-N 3.12Å; N344-H347 WeakPolarHBondContact O-CB 3.45Å; N344-H347 PolarHBondContact O-CD2 2.98Å; N344-H347 PolarHBondContact O-N 3.23Å; N344-L484 HydrophobicContact CB-CD2 4.4Å; N344-L484 PolarHBondContact ND2-O 3.42Å; N344-M487 HydrophobicContact CB-CB 4.25Å; N344-M487 HydrophobicContact CB-SD 4.11Å; N344-N488 VanDerWaalsContact CG-ND2 3.35Å; N344-N488 PolarHBondContact ND2-ND2 3.07Å; N344-N488 PolarHBondContact OD1-ND2 3.37Å; N344-N488 PolarHBondContact OD1-OD1 3.24Å
345M97.3Very high94.2Very high2 Ų242.8 Ų42.81%0.0126%0.258CS..G310 helixtrans-55.4-24.3169.4-172.364.477.800112.5L311 F315 I341 I342 T343 H347 L348 V350 I352 L484L311-M345 HydrophobicContact CD1-CE 4Å; L311-M345 HydrophobicContact CD2-CB 4.16Å; L311-M345 HydrophobicContact CD2-CE 4.32Å; L311-M345 HydrophobicContact CD2-CG 4.21Å; F315-M345 HydrophobicContact CE1-CG 4.11Å; F315-M345 HydrophobicContact CZ-CE 4.19Å; F315-M345 HydrophobicContact CZ-CG 4.1Å; F315-M345 HydrophobicContact CZ-SD 4.48Å; I341-M345 PolarHBondContact O-N 3.42Å; I342-M345 WeakPolarHBondContact O-CB 3.29Å; T343-M345 PolarHBondContact O-N 2.91Å; M345-H347 PolarHBondContact O-N 2.96Å; M345-L348 PolarHBondContact O-N 3.02Å; M345-L348 HydrophobicContact SD-CD2 3.93Å; M345-V350 HydrophobicContact CG-CB 4.09Å; M345-V350 HydrophobicContact CG-CG1 4.28Å; M345-V350 HydrophobicContact CG-CG2 4.32Å; M345-V350 HydrophobicContact SD-CG2 4.39Å; M345-I352 HydrophobicContact CB-CD1 3.79Å; M345-I352 HydrophobicContact CB-CG1 4.02Å; M345-I352 HydrophobicContact CG-CD1 3.77Å; M345-I352 HydrophobicContact CG-CG1 4.41Å; M345-L484 HydrophobicContact CE-CD1 3.42Å; M345-L484 VanDerWaalsContact CE-CD1 3.42Å; M345-L484 HydrophobicContact SD-CD1 4.26Å
346A95.9Very high92.8Very high47 Ų4742.8 Ų42.839%0.38826%0.259SS..G310 helixtrans-63.1-26.4175.200000113.6T343 N344 L348 G349 V350 I352T343-A346 WeakPolarHBondContact O-CB 3.17Å; T343-A346 PolarHBondContact O-N 3.47Å; N344-A346 PolarHBondContact O-N 3.12Å; A346-L348 PolarHBondContact O-N 2.95Å; A346-G349 PolarHBondContact O-N 2.98Å; A346-V350 WeakPolarHBondContact CA-O 3.46Å; A346-I352 HydrophobicContact CB-CB 4.42Å; A346-I352 HydrophobicContact CB-CG1 4.05Å
347H95.5Very high91.3Very high70 Ų7043.1 Ų43.132%0.32426%0.259SS..G310 helixtrans-69-19.3177.9-68-63.4000113.6Y59 N344 M345 G349 M487Y59-H347 WeakPolarHBondContact O-CB 3.5Å; N344-H347 WeakPolarHBondContact O-CB 3.45Å; N344-H347 PolarHBondContact O-CD2 2.98Å; N344-H347 PolarHBondContact O-N 3.23Å; M345-H347 PolarHBondContact O-N 2.96Å; H347-G349 PolarHBondContact O-N 3.2Å; H347-M487 HydrophobicContact CB-SD 3.42Å; H347-M487 WeakPolarHBondContact CB-SD 3.16Å; H347-M487 PolarHBondContact CD2-SD 3.41Å
348L96Very high89.7Confident3 Ų345.2 Ų45.22%0.01627%0.274CS..G310 helixtrans-78.62171.1-79.464000112F55 Y59 R137 G138 M345 A346 V350 L484 M487F55-L348 HydrophobicContact CE2-CD1 4.33Å; F55-L348 HydrophobicContact CE2-CD2 4.15Å; F55-L348 HydrophobicContact CZ-CD1 3.86Å; F55-L348 HydrophobicContact CZ-CD2 4.23Å; Y59-L348 HydrophobicContact CD1-CD1 4.15Å; Y59-L348 HydrophobicContact CD1-CG 4.04Å; Y59-L348 HydrophobicContact CD2-CD1 4.15Å; Y59-L348 HydrophobicContact CD2-CG 4.23Å; Y59-L348 HydrophobicContact CE1-CG 4.19Å; Y59-L348 HydrophobicContact CE2-CG 4.38Å; Y59-L348 HydrophobicContact CG-CD1 3.82Å; Y59-L348 HydrophobicContact CG-CG 4.08Å; R137-L348 HydrophobicContact CB-CD2 3.9Å; R137-L348 HydrophobicContact CB-CG 4.48Å; R137-L348 HydrophobicContact CG-CD2 3.71Å; G138-L348 WeakPolarHBondContact CA-O 3.48Å; M345-L348 PolarHBondContact O-N 3.02Å; M345-L348 HydrophobicContact SD-CD2 3.93Å; A346-L348 PolarHBondContact O-N 2.95Å; L348-V350 HydrophobicContact CB-CG2 4.11Å; L348-L484 HydrophobicContact CD1-CD2 3.91Å; L348-M487 HydrophobicContact CD1-CE 3.87Å
349G93.2Very high87.7Confident60 Ų6054.6 Ų54.662%0.61931%0.308SS*.THydrogen-bonded Turntrans83.113.8-175.400000113.7A346 H347A346-G349 PolarHBondContact O-N 2.98Å; H347-G349 PolarHBondContact O-N 3.2Å
350V93.8Very high86.2Confident9 Ų958.6 Ų58.66%0.05532%0.32CS..  trans-89.5132.3-179.3-175.70000110.2P141 F315 M345 A346 L348 I352P141-V350 HydrophobicContact CB-CG1 4.18Å; P141-V350 HydrophobicContact CB-CG2 3.87Å; P141-V350 HydrophobicContact CG-CG1 3.95Å; P141-V350 HydrophobicContact CG-CG2 4.09Å; F315-V350 HydrophobicContact CD1-CG1 3.82Å; F315-V350 HydrophobicContact CE1-CG1 3.55Å; M345-V350 HydrophobicContact CG-CB 4.09Å; M345-V350 HydrophobicContact CG-CG1 4.28Å; M345-V350 HydrophobicContact CG-CG2 4.32Å; M345-V350 HydrophobicContact SD-CG2 4.39Å; A346-V350 WeakPolarHBondContact CA-O 3.46Å; L348-V350 HydrophobicContact CB-CG2 4.11Å; V350-I352 HydrophobicContact CG1-CD1 4.1Å; V350-I352 PolarHBondContact O-N 3.06Å; V350-I352 VanDerWaalsContact O-N 3.17Å
351P93.3Very high84.7Confident46 Ų4657.1 Ų57.130%0.29933%0.326SS..  trans-73.511017926.9-31.7000111.6N318 G319 T354N318-P351 WeakPolarHBondContact OD1-CG 3.44Å; G319-P351 WeakPolarHBondContact CA-O 3.23Å; G319-P351 PolarHBondContact N-O 3.09Å; P351-T354 HydrophobicContact CB-CG2 4.05Å
352I95.4Very high83.2Confident3 Ų365.2 Ų65.22%0.01536%0.361CS..  trans-101.4-66.4177.4-55.4-57.1000111.5L311 I314 F315 G319 I320 L325 I342 M345 A346 V350L311-I352 HydrophobicContact CD2-CD1 4.38Å; I314-I352 HydrophobicContact CD1-CG2 4.19Å; I314-I352 HydrophobicContact CG2-CB 4.48Å; I314-I352 HydrophobicContact CG2-CD1 3.89Å; I314-I352 HydrophobicContact CG2-CG2 4.37Å; F315-I352 HydrophobicContact CE1-CD1 3.96Å; G319-I352 VanDerWaalsContact CA-O 3.3Å; G319-I352 WeakPolarHBondContact CA-O 3.31Å; I320-I352 PolarHBondContact N-O 3.28Å; L325-I352 HydrophobicContact CD2-CG2 4.43Å; I342-I352 HydrophobicContact CG2-CG2 3.97Å; I342-I352 WeakPolarHBondContact O-CG2 3.48Å; M345-I352 HydrophobicContact CB-CD1 3.79Å; M345-I352 HydrophobicContact CB-CG1 4.02Å; M345-I352 HydrophobicContact CG-CD1 3.77Å; M345-I352 HydrophobicContact CG-CG1 4.41Å; A346-I352 HydrophobicContact CB-CB 4.42Å; A346-I352 HydrophobicContact CB-CG1 4.05Å; V350-I352 HydrophobicContact CG1-CD1 4.1Å; V350-I352 PolarHBondContact O-N 3.06Å; V350-I352 VanDerWaalsContact O-N 3.17Å
353V94.4Very high81.8Confident61 Ų6170.1 Ų70.137%0.3738%0.383SS..BIsolated β-bridgetrans-100.8122.2176.3-176.90000109.3I320 E322 L325I320-V353 CarbonylContact O-C 3.55Å; I320-V353 VanDerWaalsContact O-CA 3.3Å; I320-V353 WeakPolarHBondContact O-CA 3.32Å; E322-V353 HydrophobicContact CB-CG1 3.96Å; L325-V353 HydrophobicContact CD2-CG2 3.77Å
354T88Confident80.5Confident17 Ų1770.9 Ų70.910%0.10438%0.383CS..  trans-136.1110.4-178.960.70000110.9G319 I320 P351G319-T354 VanDerWaalsContact C-OG1 3.25Å; G319-T354 PolarHBondContact O-OG1 3.01Å; I320-T354 PolarHBondContact O-N 3.07Å; P351-T354 HydrophobicContact CB-CG2 4.05Å
355D76.8Confident79.5Confident136 Ų13676.8 Ų76.873%0.72742%0.415SS*.SBendtrans-82.3-15.6179-59.4-40000113.6
356S66.7Low79.1Confident45 Ų4580.9 Ų80.932%0.31543%0.43SS..  trans-127.7135.4-178.165.60000112L358 R359S356-L358 PolarHBondContact O-N 2.97Å; S356-R359 PolarHBondContact O-N 3.39Å
357T63Low78.7Confident110 Ų11081.4 Ų81.468%0.67542%0.423SS*.G310 helixtrans-65.2-19.2175.150.80000112.9R359 R360T357-R359 VanDerWaalsContact C-N 3.34Å; T357-R359 PolarHBondContact O-N 3.16Å; T357-R360 PolarHBondContact O-N 3.23Å
358L56.8Low77.9Confident163 Ų16387.4 Ų87.485%0.85345%0.452SS*.G310 helixtrans-70.9-22.8-178.9-73.3162.4000114S356S356-L358 PolarHBondContact O-N 2.97Å
359R55.8Low77Confident209 Ų20990.3 Ų90.379%0.78946%0.462SS*.G310 helixtrans-90.21.8-179.8-68.7-171.6-178.5-170.11.4113.9S356 T357 G361S356-R359 PolarHBondContact O-N 3.39Å; T357-R359 VanDerWaalsContact C-N 3.34Å; T357-R359 PolarHBondContact O-N 3.16Å; R359-G361 PolarHBondContact O-N 2.8Å; R359-G361 VanDerWaalsContact O-N 3.12Å
360R64.3Low75.5Confident109 Ų10991.9 Ų91.941%0.41146%0.46SS..  trans-75.8102.2179.3-69.8-172.7172166.2-2.4109.7N318 G319 T357N318-R360 WeakPolarHBondContact ND2-CA 3.48Å; N318-R360 WeakPolarHBondContact ND2-CB 3.36Å; G319-R360 PolarHBondContact O-NH2 3.03Å; T357-R360 PolarHBondContact O-N 3.23Å
361G63.6Low74.2Confident50 Ų5094.3 Ų94.352%0.51548%0.477SS..PPolyproline II helixtrans-57.9153.6173.100000112.3N318 R359 K363N318-G361 PolarHBondContact ND2-N 2.72Å; N318-G361 PolarHBondContact ND2-O 3.45Å; R359-G361 PolarHBondContact O-N 2.8Å; R359-G361 VanDerWaalsContact O-N 3.12Å; G361-K363 PolarHBondContact O-N 3.12Å
362K66.1Low72.4Confident170 Ų170101.7 Ų101.774%0.73951%0.508SS*.PPolyproline II helixtrans-69.2127.5174.2-167.4-167.6170.6-158.50108.2D365K362-D365 IonicContact NZ-OD1 2.95Å; K362-D365 IonicContact NZ-OD2 2.66Å; K362-D365 PolarHBondContact NZ-OD2 2.92Å
363K68.2Low71.1Confident104 Ų104110 Ų11045%0.45255%0.546SS..PPolyproline II helixtrans-62.5139.5169.6-73.6-172.4171.4-1750109.3F315 L316 G361 D365F315-K363 VanDerWaalsContact O-CE 3.25Å; F315-K363 WeakPolarHBondContact O-CE 3.34Å; F315-K363 PolarHBondContact O-NZ 2.81Å; L316-K363 PolarHBondContact O-NZ 3.32Å; G361-K363 PolarHBondContact O-N 3.12Å; K363-D365 PolarHBondContact O-N 3.39Å
364M70.1Confident70.5Confident72 Ų72109.5 Ų109.536%0.35554%0.544SS..PPolyproline II helixtrans-60.2133.6170.9-74.8-174.266.400109.3R366 L383 Y401M364-R366 PolarHBondContact O-N 3.4Å; M364-L383 HydrophobicContact SD-CD2 4.17Å; M364-Y401 HydrophobicContact CE-CE2 4.08Å
365D76.4Confident70.6Confident126 Ų126113.2 Ų113.267%0.67456%0.557SS**PPolyproline II helixtrans-66.9125176.5-63.6-43.2000108K362 K363K362-D365 IonicContact NZ-OD1 2.95Å; K362-D365 IonicContact NZ-OD2 2.66Å; K362-D365 PolarHBondContact NZ-OD2 2.92Å; K363-D365 PolarHBondContact O-N 3.39Å
366R88.9Confident71.3Confident89 Ų89112.5 Ų112.534%0.33655%0.549SS..PPolyproline II helixtrans-83.3146.1-178.1-62.2-58.5-51.2-76.1-5.5110.1M364 T381 D386M364-R366 PolarHBondContact O-N 3.4Å; R366-T381 PolarHBondContact NH1-O 3.04Å; R366-T381 PolarHBondContact NH2-O 3.31Å; R366-D386 IonicContact CZ-OD2 3.79Å; R366-D386 IonicContact NE-OD2 3.42Å; R366-D386 PolarHBondContact NE-OD2 3.3Å; R366-D386 IonicContact NH2-OD1 3.4Å; R366-D386 IonicContact NH2-OD2 3.61Å; R366-D386 PolarHBondContact NH2-OD2 3.25Å
367K86.9Confident72.6Confident57 Ų57111.4 Ų111.425%0.24854%0.539CS..PPolyproline II helixtrans-66.7135.5168.8-77.6178.5172.5171.90110R369 D386 E389 D390K367-R369 HydrophobicContact CB-CG 4.21Å; K367-R369 PolarHBondContact O-N 3.12Å; K367-D386 HydrophobicContact CD-CB 4.28Å; K367-D386 HydrophobicContact CG-CB 4.48Å; K367-D386 PolarHBondContact N-OD2 3.09Å; K367-D386 PolarHBondContact NZ-O 3.17Å; K367-E389 VanDerWaalsContact NZ-CB 3.26Å; K367-E389 IonicContact NZ-OE2 2.67Å; K367-E389 PolarHBondContact NZ-OE2 3.26Å; K367-D390 WeakPolarHBondContact CE-OD1 3.3Å; K367-D390 VanDerWaalsContact CE-OD2 3.29Å; K367-D390 WeakPolarHBondContact CE-OD2 3.28Å; K367-D390 IonicContact NZ-OD1 2.78Å; K367-D390 PolarHBondContact NZ-OD1 3.3Å; K367-D390 IonicContact NZ-OD2 3.86Å
368E77.9Confident74.1Confident196 Ų196107.5 Ų107.592%0.91652%0.517SS*.PPolyproline II helixtrans-73.7117.2174.4-168.8172.7-171.300109.4
369R77.8Confident75.9Confident64 Ų64100.7 Ų100.724%0.24248%0.479CS..  trans-134.8-8.6-170.9-65176.1-177.3-77.96.4114.4K367 S371 D386 E389K367-R369 HydrophobicContact CB-CG 4.21Å; K367-R369 PolarHBondContact O-N 3.12Å; R369-S371 PolarHBondContact O-N 2.93Å; R369-D386 IonicContact CZ-OD1 2.8Å; R369-D386 IonicContact NE-OD1 3.53Å; R369-D386 PolarHBondContact NE-OD1 3.09Å; R369-D386 IonicContact NH2-OD1 2.67Å; R369-D386 PolarHBondContact NH2-OD1 3.38Å; R369-E389 IonicContact CZ-OE1 3.69Å; R369-E389 IonicContact CZ-OE2 3.41Å; R369-E389 IonicContact NH1-OE1 2.81Å; R369-E389 PolarHBondContact NH1-OE1 3.08Å; R369-E389 IonicContact NH1-OE2 2.75Å; R369-E389 PolarHBondContact NH1-OE2 3.23Å; R369-E389 IonicContact NH2-OE1 3.61Å; R369-E389 PolarHBondContact NH2-OE1 3.37Å; R369-E389 IonicContact NH2-OE2 2.88Å; R369-E389 PolarHBondContact NH2-OE2 3.19Å
370V61.9Low77.8Confident94 Ų9491.8 Ų91.857%0.5745%0.446SS*.  trans-67.5113.9-173.9-175.60000108.2M276M276-V370 HydrophobicContact CE-CG2 4.06Å
371S65.8Low79.4Confident60 Ų6088 Ų8842%0.4243%0.434SS..  trans-109.2156.6177.2170.40000109R369 Q373 T374R369-S371 PolarHBondContact O-N 2.93Å; S371-Q373 PolarHBondContact O-N 3.04Å; S371-Q373 PolarHBondContact OG-N 3.46Å; S371-T374 PolarHBondContact N-OG1 3.22Å; S371-T374 WeakPolarHBondContact O-CB 3.42Å; S371-T374 PolarHBondContact O-N 3.18Å; S371-T374 PolarHBondContact O-OG1 3.39Å
372E56.8Low81Confident201 Ų20185.6 Ų85.694%0.93941%0.41SS*.THydrogen-bonded Turntrans-57.2-18.9172-65.3-178.2172.900112.9
373Q66.3Low82.4Confident177 Ų17778.2 Ų78.283%0.82738%0.378SS*.THydrogen-bonded Turntrans-86.6-6.2178.6-64.2-179.3-12.700113.9S371S371-Q373 PolarHBondContact O-N 3.04Å; S371-Q373 PolarHBondContact OG-N 3.46Å
374T83.1Confident83.9Confident51 Ų5173.2 Ų73.231%0.31336%0.357SS..SBendtrans-77.4127.2-179.4-54.90000110.5S371 Q376 S378 R379S371-T374 PolarHBondContact N-OG1 3.22Å; S371-T374 WeakPolarHBondContact O-CB 3.42Å; S371-T374 PolarHBondContact O-N 3.18Å; S371-T374 PolarHBondContact O-OG1 3.39Å; T374-Q376 PolarHBondContact O-N 3.38Å; T374-S378 VanDerWaalsContact CG2-O 3.25Å; T374-S378 WeakPolarHBondContact CG2-O 3.44Å; T374-R379 HydrophobicContact CG2-CG 4.42Å
375Y90.3Very high85.2Confident95 Ų9571.6 Ų71.637%0.37335%0.348SS..  trans-60136.4173.6-71-82.4000110.9H197 A199 E200 L377 S378H197-Y375 HydrophobicContact CB-CD2 4.14Å; H197-Y375 HydrophobicContact CB-CE2 3.77Å; H197-Y375 AromaticContact CD2-CD2 3.68Å; H197-Y375 AromaticContact CE1-CD1 3.86Å; H197-Y375 AromaticContact CE1-CD2 3.92Å; H197-Y375 AromaticContact CE1-CG 3.76Å; H197-Y375 AromaticContact CG-CD2 3.6Å; H197-Y375 AromaticContact CG-CE2 3.57Å; H197-Y375 AromaticContact ND1-CD2 3.75Å; H197-Y375 AromaticContact ND1-CE1 3.99Å; H197-Y375 AromaticContact ND1-CE2 3.6Å; H197-Y375 AromaticContact ND1-CZ 3.73Å; H197-Y375 AromaticContact NE2-CD2 3.89Å; H197-Y375 AromaticContact NE2-CG 3.79Å; A199-Y375 HydrophobicContact CB-CE1 4.06Å; E200-Y375 WeakPolarHBondContact CG-OH 3.36Å; E200-Y375 PolarHBondContact OE1-OH 3.47Å; Y375-L377 PolarHBondContact O-N 3.27Å; Y375-S378 CarbonylContact O-C 3.5Å; Y375-S378 PolarHBondContact O-N 3.39Å
376Q90.3Very high86.2Confident121 Ų12165.9 Ų65.957%0.56532%0.317SS*.THydrogen-bonded Turntrans-55.6-30.9-175.3-70.1-175.4-2200114A280 T374 R379A280-Q376 HydrophobicContact CB-CG 4.37Å; T374-Q376 PolarHBondContact O-N 3.38Å; Q376-R379 WeakPolarHBondContact O-CD 3.15Å; Q376-R379 WeakPolarHBondContact O-CG 3.38Å; Q376-R379 PolarHBondContact O-NE 2.85Å
377L94Very high86.6Confident22 Ų2261.7 Ų61.712%0.11530%0.302CS..THydrogen-bonded Turntrans-98.611.4-179.4-56.6-179.2000113.3L149 Y260 D265 C268 R269 Q272 Y375L149-L377 HydrophobicContact CD1-CB 3.81Å; Y260-L377 WeakPolarHBondContact OH-CD1 3.05Å; D265-L377 WeakPolarHBondContact OD1-CD1 2.96Å; C268-L377 HydrophobicContact CB-CB 4.31Å; C268-L377 HydrophobicContact CB-CD1 4.35Å; C268-L377 HydrophobicContact CB-CD2 4.47Å; R269-L377 HydrophobicContact CB-CD2 4.25Å; R269-L377 HydrophobicContact CG-CD2 3.49Å; R269-L377 VanDerWaalsContact CG-CD2 3.49Å; Q272-L377 WeakPolarHBondContact CG-O 3.45Å; Q272-L377 PolarHBondContact NE2-O 3.35Å; Y375-L377 PolarHBondContact O-N 3.27Å
378S95.3Very high87.1Confident28 Ų2859 Ų5920%0.19629%0.29CS..  trans-13946.5178.7-52.10000110.5H197 T374 Y375H197-S378 PolarHBondContact NE2-OG 2.86Å; T374-S378 VanDerWaalsContact CG2-O 3.25Å; T374-S378 WeakPolarHBondContact CG2-O 3.44Å; Y375-S378 CarbonylContact O-C 3.5Å; Y375-S378 PolarHBondContact O-N 3.39Å
379R94.7Very high88Confident20 Ų2051.9 Ų51.98%0.07526%0.256CS..  trans-79.7-34.4-179-69.8178.6-74.6145.4-1.5112.1Q272 D273 M276 T278 D279 T374 Q376 T381Q272-R379 VanDerWaalsContact CB-NH2 3.31Å; D273-R379 IonicContact OD1-CZ 3.68Å; D273-R379 IonicContact OD1-NH1 3.76Å; D273-R379 IonicContact OD1-NH2 2.7Å; D273-R379 PolarHBondContact OD1-NH2 3.2Å; M276-R379 HydrophobicContact CE-CB 4.2Å; M276-R379 HydrophobicContact CG-CB 3.98Å; M276-R379 HydrophobicContact SD-CB 4.16Å; T278-R379 PolarHBondContact O-NH1 3.39Å; D279-R379 PolarHBondContact O-NH1 2.74Å; T374-R379 HydrophobicContact CG2-CG 4.42Å; Q376-R379 WeakPolarHBondContact O-CD 3.15Å; Q376-R379 WeakPolarHBondContact O-CG 3.38Å; Q376-R379 PolarHBondContact O-NE 2.85Å; R379-T381 PolarHBondContact O-N 3.3Å
380W95.6Very high89Confident22 Ų2250.6 Ų50.68%0.08325%0.254CS..  trans-61.4134.5178178.7-101.4000111.3V142 S143 L146 A275 M276V142-W380 HydrophobicContact CB-CH2 3.82Å; V142-W380 HydrophobicContact CB-CZ2 3.62Å; V142-W380 HydrophobicContact CG1-CD2 3.94Å; V142-W380 HydrophobicContact CG1-CE3 4.13Å; V142-W380 HydrophobicContact CG1-CH2 3.69Å; V142-W380 HydrophobicContact CG1-CZ2 3.51Å; V142-W380 HydrophobicContact CG1-CZ3 3.99Å; V142-W380 HydrophobicContact CG2-CH2 4.15Å; V142-W380 HydrophobicContact CG2-CZ2 4.43Å; S143-W380 PolarHBondContact OG-NE1 3.12Å; L146-W380 HydrophobicContact CD1-CB 3.74Å; L146-W380 HydrophobicContact CD1-CD2 3.97Å; L146-W380 HydrophobicContact CD1-CG 3.36Å; A275-W380 HydrophobicContact CB-CB 4.49Å; A275-W380 HydrophobicContact CB-CD2 4.17Å; A275-W380 HydrophobicContact CB-CE3 3.74Å; A275-W380 HydrophobicContact CB-CZ3 4.29Å; A275-W380 WeakPolarHBondContact O-CZ3 3.16Å; M276-W380 HydrophobicContact SD-CB 4.25Å; M276-W380 HydrophobicContact SD-CE3 4.01Å
381T96.4Very high90.6Very high28 Ų2846.1 Ų46.117%0.17223%0.227CC..  trans-114.8131.4167.3-63.30000107.5R366 R379 K385R366-T381 PolarHBondContact NH1-O 3.04Å; R366-T381 PolarHBondContact NH2-O 3.31Å; R379-T381 PolarHBondContact O-N 3.3Å; T381-K385 HydrophobicContact CG2-CB 3.82Å; T381-K385 HydrophobicContact CG2-CD 3.6Å; T381-K385 HydrophobicContact CG2-CG 4.27Å
382P97.6Very high92.1Very high0 Ų043.7 Ų43.70%021%0.21CC..  trans-56.7140.7174.6-29.537.3000113.3S143 I384 K385 E451S143-P382 VanDerWaalsContact OG-CA 3.25Å; S143-P382 WeakPolarHBondContact OG-CA 3.34Å; S143-P382 WeakPolarHBondContact OG-CB 3.26Å; P382-I384 HydrophobicContact CB-CG2 3.97Å; P382-I384 PolarHBondContact O-N 3.39Å; P382-I384 VanDerWaalsContact O-N 3.14Å; P382-K385 WeakPolarHBondContact O-CB 3.39Å; P382-K385 PolarHBondContact O-N 2.66Å; P382-E451 HydrophobicContact CB-CG 4.11Å
383L96.7Very high93.9Very high15 Ų1537.8 Ų37.88%0.07919%0.185CC..Hα-helixtrans-60.6-28.2-178.1-179.262000111.7F139 D140 M364 K385 D386 I387F139-L383 HydrophobicContact CD2-CD2 4.17Å; F139-L383 HydrophobicContact CE2-CB 4.43Å; F139-L383 WeakPolarHBondContact O-CD2 3.45Å; D140-L383 HydrophobicContact CB-CB 4.03Å; D140-L383 WeakPolarHBondContact OD2-CB 3.31Å; D140-L383 PolarHBondContact OD2-N 2.67Å; M364-L383 HydrophobicContact SD-CD2 4.17Å; L383-K385 PolarHBondContact O-N 2.84Å; L383-D386 HydrophobicContact CD1-CB 4.25Å; L383-D386 WeakPolarHBondContact O-CB 3.28Å; L383-D386 PolarHBondContact O-N 2.96Å; L383-I387 HydrophobicContact CG-CD1 4.23Å; L383-I387 PolarHBondContact O-N 3.38Å; L383-I387 VanDerWaalsContact O-N 3.16Å
384I98.2Very high95.2Very high0 Ų032.4 Ų32.40%016%0.162CC..Hα-helixtrans-58.6-30.4177.9-167.656.6000113L135 F139 P382 D386 I387 M388 V441 E451 C454 I469L135-I384 HydrophobicContact CD1-CD1 3.42Å; L135-I384 VanDerWaalsContact CD1-CD1 3.42Å; F139-I384 HydrophobicContact CE2-CB 4.07Å; F139-I384 HydrophobicContact CE2-CD1 4.33Å; F139-I384 HydrophobicContact CZ-CB 4.09Å; F139-I384 HydrophobicContact CZ-CD1 4.44Å; P382-I384 HydrophobicContact CB-CG2 3.97Å; P382-I384 PolarHBondContact O-N 3.39Å; P382-I384 VanDerWaalsContact O-N 3.14Å; I384-D386 VanDerWaalsContact C-N 3.34Å; I384-I387 HydrophobicContact CD1-CB 4.21Å; I384-I387 HydrophobicContact CD1-CD1 4.3Å; I384-I387 HydrophobicContact CD1-CG2 4.31Å; I384-I387 PolarHBondContact O-N 2.6Å; I384-M388 HydrophobicContact CD1-CE 4.46Å; I384-M388 HydrophobicContact CD1-CG 4.4Å; I384-M388 HydrophobicContact CG1-CE 3.75Å; I384-M388 HydrophobicContact CG1-CG 4.18Å; I384-M388 HydrophobicContact CG1-SD 4.19Å; I384-M388 WeakPolarHBondContact O-CB 3.45Å; I384-M388 VanDerWaalsContact O-CG 3.27Å; I384-M388 WeakPolarHBondContact O-CG 3.34Å; I384-M388 PolarHBondContact O-N 2.89Å; I384-V441 HydrophobicContact CD1-CG1 3.66Å; I384-V441 HydrophobicContact CD1-CG2 4.27Å; I384-V441 HydrophobicContact CG1-CG1 4.3Å; I384-E451 HydrophobicContact CG2-CB 3.85Å; I384-E451 HydrophobicContact CG2-CG 3.79Å; I384-C454 HydrophobicContact CG2-CB 4.07Å; I384-I469 HydrophobicContact CG1-CD1 4.29Å
385K98.1Very high95.8Very high37 Ų3736.5 Ų36.516%0.16118%0.175CC..Hα-helixtrans-65.4-40.2176.3-164.4175.3-179.1175.10111.6T381 P382 L383 M388 E389 C454 E457 V458T381-K385 HydrophobicContact CG2-CB 3.82Å; T381-K385 HydrophobicContact CG2-CD 3.6Å; T381-K385 HydrophobicContact CG2-CG 4.27Å; P382-K385 WeakPolarHBondContact O-CB 3.39Å; P382-K385 PolarHBondContact O-N 2.66Å; L383-K385 PolarHBondContact O-N 2.84Å; K385-M388 PolarHBondContact O-N 3.45Å; K385-E389 WeakPolarHBondContact O-CB 3.39Å; K385-E389 WeakPolarHBondContact O-CG 3.33Å; K385-E389 PolarHBondContact O-N 3.46Å; K385-C454 HydrophobicContact CB-CB 4Å; K385-C454 HydrophobicContact CG-CB 4.29Å; K385-E457 WeakPolarHBondContact CE-OE2 3.36Å; K385-E457 IonicContact NZ-OE2 3.3Å; K385-E457 PolarHBondContact NZ-OE2 3Å; K385-V458 HydrophobicContact CG-CG2 3.83Å
386D97.1Very high96Very high6 Ų632.5 Ų32.53%0.03216%0.16CC..Hα-helixtrans-61-49.2175.4-60.1-9.8000109.8R366 K367 R369 L383 I384 M388 E389 D390R366-D386 IonicContact CZ-OD2 3.79Å; R366-D386 IonicContact NE-OD2 3.42Å; R366-D386 PolarHBondContact NE-OD2 3.3Å; R366-D386 IonicContact NH2-OD1 3.4Å; R366-D386 IonicContact NH2-OD2 3.61Å; R366-D386 PolarHBondContact NH2-OD2 3.25Å; K367-D386 HydrophobicContact CD-CB 4.28Å; K367-D386 HydrophobicContact CG-CB 4.48Å; K367-D386 PolarHBondContact N-OD2 3.09Å; K367-D386 PolarHBondContact NZ-O 3.17Å; R369-D386 IonicContact CZ-OD1 2.8Å; R369-D386 IonicContact NE-OD1 3.53Å; R369-D386 PolarHBondContact NE-OD1 3.09Å; R369-D386 IonicContact NH2-OD1 2.67Å; R369-D386 PolarHBondContact NH2-OD1 3.38Å; L383-D386 HydrophobicContact CD1-CB 4.25Å; L383-D386 WeakPolarHBondContact O-CB 3.28Å; L383-D386 PolarHBondContact O-N 2.96Å; I384-D386 VanDerWaalsContact C-N 3.34Å; D386-M388 PolarHBondContact O-N 2.83Å; D386-E389 PolarHBondContact O-N 2.74Å; D386-D390 WeakPolarHBondContact O-CB 3.42Å; D386-D390 PolarHBondContact O-N 3.42Å
387I97.8Very high96.2Very high2 Ų230.1 Ų30.11%0.0115%0.151CC..Hα-helixtrans-59.4-46.4178.3-63.7169.8000111.3I133 L135 F139 L383 I384 D390 A391 L396 Y401I133-I387 HydrophobicContact CD1-CG2 4.14Å; L135-I387 HydrophobicContact CD1-CD1 4.36Å; F139-I387 HydrophobicContact CD2-CD1 3.85Å; F139-I387 HydrophobicContact CE2-CD1 3.97Å; L383-I387 HydrophobicContact CG-CD1 4.23Å; L383-I387 PolarHBondContact O-N 3.38Å; L383-I387 VanDerWaalsContact O-N 3.16Å; I384-I387 HydrophobicContact CD1-CB 4.21Å; I384-I387 HydrophobicContact CD1-CD1 4.3Å; I384-I387 HydrophobicContact CD1-CG2 4.31Å; I384-I387 PolarHBondContact O-N 2.6Å; I387-D390 PolarHBondContact O-N 3.49Å; I387-A391 VanDerWaalsContact O-CB 3.27Å; I387-A391 WeakPolarHBondContact O-CB 3.46Å; I387-A391 PolarHBondContact O-N 3.23Å; I387-L396 HydrophobicContact CB-CD1 4.45Å; I387-L396 HydrophobicContact CG2-CD1 4.1Å; I387-L396 HydrophobicContact CG2-CD2 4.06Å; I387-Y401 HydrophobicContact CD1-CE1 4.27Å; I387-Y401 WeakPolarHBondContact CD1-OH 3.23Å
388M98.3Very high96.2Very high0 Ų033.3 Ų33.30%017%0.171CC..Hα-helixtrans-63.9-48.5-177.9-76.2175171.500112I384 K385 D386 A391 I392 L439 V441 A455 V458 A467 I469I384-M388 HydrophobicContact CD1-CE 4.46Å; I384-M388 HydrophobicContact CD1-CG 4.4Å; I384-M388 HydrophobicContact CG1-CE 3.75Å; I384-M388 HydrophobicContact CG1-CG 4.18Å; I384-M388 HydrophobicContact CG1-SD 4.19Å; I384-M388 WeakPolarHBondContact O-CB 3.45Å; I384-M388 VanDerWaalsContact O-CG 3.27Å; I384-M388 WeakPolarHBondContact O-CG 3.34Å; I384-M388 PolarHBondContact O-N 2.89Å; K385-M388 PolarHBondContact O-N 3.45Å; D386-M388 PolarHBondContact O-N 2.83Å; M388-A391 PolarHBondContact O-N 2.62Å; M388-I392 WeakPolarHBondContact O-CG1 3.37Å; M388-I392 PolarHBondContact O-N 3.16Å; M388-L439 HydrophobicContact CB-CD2 3.78Å; M388-L439 HydrophobicContact CG-CD2 3.83Å; M388-L439 WeakPolarHBondContact O-CD2 3.4Å; M388-V441 HydrophobicContact CE-CB 4.14Å; M388-V441 HydrophobicContact CE-CG2 3.72Å; M388-V441 HydrophobicContact CG-CG2 4.13Å; M388-A455 HydrophobicContact CE-CB 4Å; M388-A455 HydrophobicContact SD-CB 4.42Å; M388-V458 HydrophobicContact CB-CG1 4.25Å; M388-V458 HydrophobicContact CB-CG2 4.16Å; M388-V458 HydrophobicContact SD-CG2 4.45Å; M388-A467 HydrophobicContact SD-CB 4.34Å; M388-I469 HydrophobicContact CE-CB 3.97Å; M388-I469 HydrophobicContact CE-CD1 3.98Å; M388-I469 HydrophobicContact CE-CG1 4.27Å
389E97Very high96.1Very high46 Ų4639.9 Ų39.922%0.21520%0.197CC..Hα-helixtrans-64.1-42.9177.4-72.1174.3-176.200111.9K367 R369 K385 D386 A391 I392 D393 V458K367-E389 VanDerWaalsContact NZ-CB 3.26Å; K367-E389 IonicContact NZ-OE2 2.67Å; K367-E389 PolarHBondContact NZ-OE2 3.26Å; R369-E389 IonicContact CZ-OE1 3.69Å; R369-E389 IonicContact CZ-OE2 3.41Å; R369-E389 IonicContact NH1-OE1 2.81Å; R369-E389 PolarHBondContact NH1-OE1 3.08Å; R369-E389 IonicContact NH1-OE2 2.75Å; R369-E389 PolarHBondContact NH1-OE2 3.23Å; R369-E389 IonicContact NH2-OE1 3.61Å; R369-E389 PolarHBondContact NH2-OE1 3.37Å; R369-E389 IonicContact NH2-OE2 2.88Å; R369-E389 PolarHBondContact NH2-OE2 3.19Å; K385-E389 WeakPolarHBondContact O-CB 3.39Å; K385-E389 WeakPolarHBondContact O-CG 3.33Å; K385-E389 PolarHBondContact O-N 3.46Å; D386-E389 PolarHBondContact O-N 2.74Å; E389-A391 VanDerWaalsContact C-N 3.31Å; E389-A391 PolarHBondContact O-N 2.53Å; E389-I392 PolarHBondContact O-N 3.45Å; E389-D393 WeakPolarHBondContact O-CB 3.39Å; E389-D393 PolarHBondContact O-N 2.81Å; E389-V458 HydrophobicContact CG-CG1 4.48Å; E389-V458 HydrophobicContact CG-CG2 3.99Å
390D96.8Very high96Very high37 Ų3742.3 Ų42.320%0.19821%0.209CC..Hα-helixtrans-66.2-33.1177.4-78.1-25.6000112.4K367 D386 I387 D394 K395 L396K367-D390 WeakPolarHBondContact CE-OD1 3.3Å; K367-D390 VanDerWaalsContact CE-OD2 3.29Å; K367-D390 WeakPolarHBondContact CE-OD2 3.28Å; K367-D390 IonicContact NZ-OD1 2.78Å; K367-D390 PolarHBondContact NZ-OD1 3.3Å; K367-D390 IonicContact NZ-OD2 3.86Å; D386-D390 WeakPolarHBondContact O-CB 3.42Å; D386-D390 PolarHBondContact O-N 3.42Å; I387-D390 PolarHBondContact O-N 3.49Å; D390-D394 CarbonylContact O-C 3.55Å; D390-D394 PolarHBondContact O-N 3.11Å; D390-K395 HydrophobicContact CB-CB 4.3Å; D390-K395 PolarHBondContact O-N 3.21Å; D390-L396 HydrophobicContact CB-CB 4.02Å; D390-L396 HydrophobicContact CB-CD1 4.13Å; D390-L396 PolarHBondContact O-N 2.92Å
391A96.8Very high96.1Very high0 Ų041.4 Ų41.40%021%0.205CC..Hα-helixtrans-67.8-41.4175.100000112Q131 I133 I387 M388 E389 D394 L396 L439Q131-A391 PolarHBondContact NE2-O 3.21Å; I133-A391 HydrophobicContact CD1-CB 3.68Å; I387-A391 VanDerWaalsContact O-CB 3.27Å; I387-A391 WeakPolarHBondContact O-CB 3.46Å; I387-A391 PolarHBondContact O-N 3.23Å; M388-A391 PolarHBondContact O-N 2.62Å; E389-A391 VanDerWaalsContact C-N 3.31Å; E389-A391 PolarHBondContact O-N 2.53Å; A391-D394 PolarHBondContact O-N 3.24Å; A391-L396 HydrophobicContact CB-CB 4.4Å; A391-L396 HydrophobicContact CB-CD2 4.1Å; A391-L439 HydrophobicContact CB-CD1 3.87Å; A391-L439 HydrophobicContact CB-CD2 3.96Å
392I96Very high96.1Very high9 Ų941.3 Ų41.35%0.04621%0.205CC..Hα-helixtrans-66.4-38.7177.7-75.4167.3000111.5M388 E389 D394 L439 V458 N462 W465M388-I392 WeakPolarHBondContact O-CG1 3.37Å; M388-I392 PolarHBondContact O-N 3.16Å; E389-I392 PolarHBondContact O-N 3.45Å; I392-D394 PolarHBondContact O-N 3.43Å; I392-L439 HydrophobicContact CD1-CD2 4.24Å; I392-L439 HydrophobicContact CG1-CB 4.42Å; I392-L439 HydrophobicContact CG1-CD2 4.07Å; I392-V458 HydrophobicContact CD1-CG1 3.36Å; I392-N462 VanDerWaalsContact CG2-ND2 3.34Å; I392-N462 WeakPolarHBondContact CG2-ND2 3.36Å; I392-W465 HydrophobicContact CB-CD2 4.39Å; I392-W465 HydrophobicContact CB-CG 4.46Å; I392-W465 HydrophobicContact CD1-CB 3.94Å; I392-W465 HydrophobicContact CD1-CG 4.32Å; I392-W465 HydrophobicContact CG1-CB 4.11Å; I392-W465 HydrophobicContact CG1-CD2 3.85Å; I392-W465 HydrophobicContact CG1-CE3 3.95Å; I392-W465 HydrophobicContact CG1-CG 3.96Å; I392-W465 HydrophobicContact CG2-CB 4.36Å; I392-W465 HydrophobicContact CG2-CD2 4.12Å; I392-W465 HydrophobicContact CG2-CG 3.82Å
393D95.3Very high96Very high78 Ų7843.5 Ų43.542%0.41721%0.214SC..THydrogen-bonded Turntrans-80.50.6177.5-82.46.2000113.5E389 K395E389-D393 WeakPolarHBondContact O-CB 3.39Å; E389-D393 PolarHBondContact O-N 2.81Å; D393-K395 HydrophobicContact CB-CB 4.44Å; D393-K395 HydrophobicContact CB-CD 3.9Å; D393-K395 HydrophobicContact CB-CG 4.04Å; D393-K395 PolarHBondContact O-N 2.99Å; D393-K395 IonicContact OD2-NZ 3.52Å; D393-K395 PolarHBondContact OD2-NZ 2.98Å
394D94.6Very high95.8Very high64 Ų6444.6 Ų44.634%0.34222%0.219SC..THydrogen-bonded Turntrans54.629.4-172.4-77.3-55.9000113.3D390 A391 I392 R407D390-D394 CarbonylContact O-C 3.55Å; D390-D394 PolarHBondContact O-N 3.11Å; A391-D394 PolarHBondContact O-N 3.24Å; I392-D394 PolarHBondContact O-N 3.43Å; D394-R407 IonicContact OD1-CZ 3.02Å; D394-R407 IonicContact OD1-NH1 3.78Å; D394-R407 PolarHBondContact OD1-NH1 3.03Å; D394-R407 IonicContact OD1-NH2 3.18Å; D394-R407 PolarHBondContact OD1-NH2 3.45Å; D394-R407 IonicContact OD2-NH2 3.89Å
395K95.4Very high95.2Very high137 Ų13747.4 Ų47.460%0.59624%0.239SC*.  trans-100.7-7.9176.7-68.1172.3-168.8151.60113.9D390 D393 D397D390-K395 HydrophobicContact CB-CB 4.3Å; D390-K395 PolarHBondContact O-N 3.21Å; D393-K395 HydrophobicContact CB-CB 4.44Å; D393-K395 HydrophobicContact CB-CD 3.9Å; D393-K395 HydrophobicContact CB-CG 4.04Å; D393-K395 PolarHBondContact O-N 2.99Å; D393-K395 IonicContact OD2-NZ 3.52Å; D393-K395 PolarHBondContact OD2-NZ 2.98Å; K395-D397 PolarHBondContact O-N 3.44Å
396L95.1Very high93.5Very high10 Ų1052.6 Ų52.65%0.05227%0.274CS..SBendtrans-66.1118.5-179.4-171.969.8000110.5R92 I133 I387 D390 A391 T398 Y401R92-L396 PolarHBondContact NH2-O 3.44Å; I133-L396 HydrophobicContact CD1-CD2 3.75Å; I387-L396 HydrophobicContact CB-CD1 4.45Å; I387-L396 HydrophobicContact CG2-CD1 4.1Å; I387-L396 HydrophobicContact CG2-CD2 4.06Å; D390-L396 HydrophobicContact CB-CB 4.02Å; D390-L396 HydrophobicContact CB-CD1 4.13Å; D390-L396 PolarHBondContact O-N 2.92Å; A391-L396 HydrophobicContact CB-CB 4.4Å; A391-L396 HydrophobicContact CB-CD2 4.1Å; L396-T398 PolarHBondContact O-N 3.39Å; L396-Y401 HydrophobicContact CD1-CD2 3.57Å; L396-Y401 HydrophobicContact CD1-CE2 3.76Å; L396-Y401 HydrophobicContact CD1-CG 4.11Å; L396-Y401 HydrophobicContact CD2-CD1 4.16Å; L396-Y401 HydrophobicContact CD2-CD2 4.05Å; L396-Y401 HydrophobicContact CD2-CG 3.72Å; L396-Y401 HydrophobicContact CG-CD2 3.67Å; L396-Y401 HydrophobicContact CG-CE2 4.38Å; L396-Y401 HydrophobicContact CG-CG 3.85Å
397D93.6Very high91.4Very high71 Ų7155.9 Ų55.938%0.3829%0.286SS..  trans-55120.1-174.1-176.8-7.9000112.3K395 K399 H400 Y401K395-D397 PolarHBondContact O-N 3.44Å; D397-K399 PolarHBondContact O-N 3.48Å; D397-K399 WeakPolarHBondContact OD1-CB 3.49Å; D397-K399 PolarHBondContact OD1-N 2.99Å; D397-H400 PolarHBondContact O-N 3.33Å; D397-H400 IonicContact OD2-CE1 2.66Å; D397-H400 PolarHBondContact OD2-CE1 2.88Å; D397-H400 IonicContact OD2-CG 3.63Å; D397-H400 IonicContact OD2-ND1 2.79Å; D397-H400 PolarHBondContact OD2-ND1 3.5Å; D397-Y401 WeakPolarHBondContact O-CA 3.49Å; D397-Y401 WeakPolarHBondContact O-CB 3.29Å; D397-Y401 PolarHBondContact O-N 3.15Å
398T94.1Very high88.9Confident89 Ų8959.9 Ų59.955%0.54631%0.314SS..THydrogen-bonded Turntrans-71.7-15.2179.9550000113.8L396 P402 Y403L396-T398 PolarHBondContact O-N 3.39Å; T398-P402 WeakPolarHBondContact O-CA 3.45Å; T398-P402 WeakPolarHBondContact O-CB 3.38Å; T398-Y403 HydrophobicContact CG2-CE2 4.26Å
399K92.7Very high86.2Confident167 Ų16765 Ų6573%0.72635%0.35SS*.THydrogen-bonded Turntrans-74.8-43.6173.3-176.1-175.9173.9-172.80111.3D397D397-K399 PolarHBondContact O-N 3.48Å; D397-K399 WeakPolarHBondContact OD1-CB 3.49Å; D397-K399 PolarHBondContact OD1-N 2.99Å
400H93.3Very high83.4Confident70 Ų7066.7 Ų66.732%0.32437%0.371SS..THydrogen-bonded Turntrans-84.5-29.8178.4-63111.6000112.1R94 G95 D397 P402R94-H400 WeakPolarHBondContact CA-O 3.45Å; G95-H400 PolarHBondContact N-O 2.83Å; D397-H400 PolarHBondContact O-N 3.33Å; D397-H400 IonicContact OD2-CE1 2.66Å; D397-H400 PolarHBondContact OD2-CE1 2.88Å; D397-H400 IonicContact OD2-CG 3.63Å; D397-H400 IonicContact OD2-ND1 2.79Å; D397-H400 PolarHBondContact OD2-ND1 3.5Å; H400-P402 VanDerWaalsContact C-CD 3.42Å; H400-P402 WeakPolarHBondContact O-CD 3.48Å
401Y96.8Very high80.7Confident3 Ų367.9 Ų67.91%0.01238%0.383CS..SBendtrans-126.265.7179.7-58.2-89.4000111.6R92 Y93 R94 I133 L135 M364 I387 L396 D397R92-Y401 PolarHBondContact NE-O 3.42Å; R92-Y401 PolarHBondContact NH2-O 2.66Å; Y93-Y401 VanDerWaalsContact O-CA 3.28Å; Y93-Y401 WeakPolarHBondContact O-CA 3.31Å; R94-Y401 HydrophobicContact CB-CD1 4.08Å; R94-Y401 HydrophobicContact CB-CE1 3.78Å; R94-Y401 HydrophobicContact CG-CE1 4Å; I133-Y401 HydrophobicContact CG2-CD1 4.37Å; L135-Y401 HydrophobicContact CD2-CD1 4.33Å; L135-Y401 HydrophobicContact CD2-CE1 3.7Å; M364-Y401 HydrophobicContact CE-CE2 4.08Å; I387-Y401 HydrophobicContact CD1-CE1 4.27Å; I387-Y401 WeakPolarHBondContact CD1-OH 3.23Å; L396-Y401 HydrophobicContact CD1-CD2 3.57Å; L396-Y401 HydrophobicContact CD1-CE2 3.76Å; L396-Y401 HydrophobicContact CD1-CG 4.11Å; L396-Y401 HydrophobicContact CD2-CD1 4.16Å; L396-Y401 HydrophobicContact CD2-CD2 4.05Å; L396-Y401 HydrophobicContact CD2-CG 3.72Å; L396-Y401 HydrophobicContact CG-CD2 3.67Å; L396-Y401 HydrophobicContact CG-CE2 4.38Å; L396-Y401 HydrophobicContact CG-CG 3.85Å; D397-Y401 WeakPolarHBondContact O-CA 3.49Å; D397-Y401 WeakPolarHBondContact O-CB 3.29Å; D397-Y401 PolarHBondContact O-N 3.15Å
402P97.1Very high78.2Confident26 Ų2672.6 Ų72.617%0.16940%0.403CS..  trans-62.8159.3178.827.7-38.1000113R92 Y93 T398 H400R92-P402 VanDerWaalsContact CA-O 3.23Å; R92-P402 WeakPolarHBondContact CA-O 3.44Å; Y93-P402 HydrophobicContact CD1-CG 4.32Å; Y93-P402 HydrophobicContact CD2-CG 4.25Å; Y93-P402 HydrophobicContact CE1-CB 4.3Å; Y93-P402 HydrophobicContact CE1-CG 3.74Å; Y93-P402 HydrophobicContact CE2-CG 3.66Å; Y93-P402 PolarHBondContact N-O 3.36Å; Y93-P402 VanDerWaalsContact O-CD 3.3Å; Y93-P402 WeakPolarHBondContact O-CD 3.46Å; T398-P402 WeakPolarHBondContact O-CA 3.45Å; T398-P402 WeakPolarHBondContact O-CB 3.38Å; H400-P402 VanDerWaalsContact C-CD 3.42Å; H400-P402 WeakPolarHBondContact O-CD 3.48Å
403Y96.1Very high75.3Confident47 Ų4776.4 Ų76.418%0.18443%0.431CS..BIsolated β-bridgetrans-89.2149.5167.9-67.5-89.7000110.3A90 V91 R92 Q131 T398 S405A90-Y403 HydrophobicContact CB-CD1 3.91Å; A90-Y403 HydrophobicContact CB-CE1 3.68Å; V91-Y403 WeakPolarHBondContact O-CA 3.33Å; R92-Y403 VanDerWaalsContact CD-CE1 3.42Å; R92-Y403 VanDerWaalsContact CD-CZ 3.49Å; R92-Y403 HydrophobicContact CG-CD1 3.35Å; R92-Y403 HydrophobicContact CG-CD2 4.41Å; R92-Y403 HydrophobicContact CG-CE1 3.31Å; R92-Y403 HydrophobicContact CG-CE2 4.39Å; R92-Y403 HydrophobicContact CG-CG 3.93Å; R92-Y403 PolarHBondContact NH1-OH 3.3Å; Q131-Y403 PolarHBondContact OE1-OH 3.42Å; T398-Y403 HydrophobicContact CG2-CE2 4.26Å; Y403-S405 WeakPolarHBondContact CB-O 3.4Å
404I92.9Very high72.6Confident37 Ų3779.3 Ų79.319%0.1945%0.451CS..SBendtrans-72-52.1170.8-70.1-68.9000110.9V91 Y93 A104 Q105 Q108V91-I404 HydrophobicContact CG1-CG1 4.33Å; V91-I404 PolarHBondContact O-N 2.67Å; Y93-I404 HydrophobicContact CD1-CD1 3.75Å; Y93-I404 HydrophobicContact CD1-CG1 3.97Å; Y93-I404 HydrophobicContact CE1-CD1 3.46Å; Y93-I404 VanDerWaalsContact CE1-CD1 3.46Å; Y93-I404 HydrophobicContact CE1-CG1 4.02Å; A104-I404 HydrophobicContact CB-CD1 3.73Å; A104-I404 HydrophobicContact CB-CG1 3.58Å; Q105-I404 HydrophobicContact CB-CD1 4.39Å; Q105-I404 VanDerWaalsContact OE1-CG2 3.29Å; Q108-I404 HydrophobicContact CB-CG2 4.01Å; Q108-I404 HydrophobicContact CG-CG2 4.01Å
405S84.1Confident69.6Low60 Ų6081.9 Ų81.942%0.4247%0.47SS..SBendtrans-102144.2178.7-65.50000110.5Y403 R407Y403-S405 WeakPolarHBondContact CB-O 3.4Å; S405-R407 PolarHBondContact O-N 3.27Å
406T61.9Low66.8Low145 Ų14580 Ų8089%0.8948%0.48SS*.PPolyproline II helixtrans-62122.2176.232.60000109.9S408T406-S408 PolarHBondContact O-N 3.32Å; T406-S408 VanDerWaalsContact O-N 3.12Å
407R54.3Low64.1Low75 Ų7586.2 Ų86.228%0.28352%0.518SS..PPolyproline II helixtrans-60.2117173.5-160.7178.3-169.1177.15.5107.5D394 S405 S409 F412D394-R407 IonicContact OD1-CZ 3.02Å; D394-R407 IonicContact OD1-NH1 3.78Å; D394-R407 PolarHBondContact OD1-NH1 3.03Å; D394-R407 IonicContact OD1-NH2 3.18Å; D394-R407 PolarHBondContact OD1-NH2 3.45Å; D394-R407 IonicContact OD2-NH2 3.89Å; S405-R407 PolarHBondContact O-N 3.27Å; R407-S409 PolarHBondContact O-N 2.98Å; R407-F412 VanDerWaalsContact CZ-CE2 3.49Å; R407-F412 VanDerWaalsContact CZ-CZ 3.47Å; R407-F412 VanDerWaalsContact NH2-CZ 3.27Å
408S45Very low61.5Low87 Ų8787 Ų8761%0.60853%0.529SS*.  trans-64.6106.1169.4380000107.6T406 A410 S411T406-S408 PolarHBondContact O-N 3.32Å; T406-S408 VanDerWaalsContact O-N 3.12Å; S408-A410 PolarHBondContact O-N 3.45Å; S408-S411 PolarHBondContact O-N 3.39Å; S408-S411 PolarHBondContact O-OG 2.84Å
409S42Very low58.9Low108 Ų10887.8 Ų87.876%0.75554%0.544SS*.G310 helixtrans-59.2-5.4179.448.30000114.2R407 S411R407-S409 PolarHBondContact O-N 2.98Å; S409-S411 VanDerWaalsContact C-N 3.34Å; S409-S411 PolarHBondContact O-N 2.91Å
410A37.8Very low56.4Low80 Ų8090.4 Ų90.466%0.66155%0.55SS*.G310 helixtrans-74.8-13-179.500000114.8S408S408-A410 PolarHBondContact O-N 3.45Å
411S40.9Very low53.6Low62 Ų6297.7 Ų97.743%0.43458%0.576SS.*G310 helixtrans-85.5-4.8-175.448.20000115S408 S409S408-S411 PolarHBondContact O-N 3.39Å; S408-S411 PolarHBondContact O-OG 2.84Å; S409-S411 VanDerWaalsContact C-N 3.34Å; S409-S411 PolarHBondContact O-N 2.91Å
412F43.6Very low50.6Low100 Ų100101 Ų10144%0.43961%0.611SS.*G310 helixtrans-91.73.7178-78.8-79.7000114.9R407 T414R407-F412 VanDerWaalsContact CZ-CE2 3.49Å; R407-F412 VanDerWaalsContact CZ-CZ 3.47Å; R407-F412 VanDerWaalsContact NH2-CZ 3.27Å; F412-T414 VanDerWaalsContact C-N 3.31Å; F412-T414 PolarHBondContact O-N 2.96Å
413S34.7Very low47.8Very low89 Ų89109.1 Ų109.162%0.62265%0.646SS**  trans-67.898.2168.971.70000108.2T415S413-T415 PolarHBondContact O-N 3.29Å
414T38Very low45.3Very low138 Ų138117.5 Ų117.585%0.84768%0.678SS**  trans-61.291.2160.644.30000106.6F412 A416F412-T414 VanDerWaalsContact C-N 3.31Å; F412-T414 PolarHBondContact O-N 2.96Å; T414-A416 VanDerWaalsContact C-N 3.28Å; T414-A416 PolarHBondContact O-N 3.27Å
415T33.1Very low42.7Very low119 Ų119123.9 Ų123.973%0.7371%0.706SS**  trans-62.4102.1162.84.90000105.3S413 V417S413-T415 PolarHBondContact O-N 3.29Å; T415-V417 WeakPolarHBondContact O-CG2 3.49Å; T415-V417 PolarHBondContact O-N 2.98Å
416A35Very low40.5Very low98 Ų98130.4 Ų130.481%0.8173%0.727SS**  trans-55.4103.8174.800000108T414 S418T414-A416 VanDerWaalsContact C-N 3.28Å; T414-A416 PolarHBondContact O-N 3.27Å; A416-S418 PolarHBondContact O-N 3.19Å
417V40.2Very low39.1Very low139 Ų139131.4 Ų131.484%0.84273%0.727SS**  trans-73104.7176.7-163.10000106.3T415 A419T415-V417 WeakPolarHBondContact O-CG2 3.49Å; T415-V417 PolarHBondContact O-N 2.98Å; V417-A419 PolarHBondContact O-N 2.92Å
418S37Very low38.2Very low87 Ų87137.7 Ų137.761%0.60876%0.756SS**  trans-50.3119.9176.7172.10000110.6A416 R420A416-S418 PolarHBondContact O-N 3.19Å; S418-R420 PolarHBondContact O-N 3.15Å; S418-R420 PolarHBondContact OG-N 3.42Å
419A39.5Very low37.6Very low106 Ų106139.2 Ų139.288%0.87676%0.762SS**THydrogen-bonded Turntrans-68.215176.400000114.2V417V417-A419 PolarHBondContact O-N 2.92Å
420R40.6Very low37.3Very low223 Ų223140.6 Ų140.684%0.84277%0.768SS**THydrogen-bonded Turntrans-103.511-171.3-63.9-168.2-157.3-157.64.8116S418S418-R420 PolarHBondContact O-N 3.15Å; S418-R420 PolarHBondContact OG-N 3.42Å
421Y34Very low37.3Very low223 Ų223139.9 Ų139.988%0.87577%0.769SS**SBendtrans-127.997171.9-131.9-99000113.7
422G34.5Very low37.4Very low72 Ų72144.3 Ų144.374%0.74278%0.783SS**  trans2.7109.3159.800000119.9W424G422-W424 VanDerWaalsContact C-N 3.34Å; G422-W424 PolarHBondContact O-N 3.2Å
423H39.1Very low37.5Very low197 Ų197149.8 Ų149.891%0.91280%0.802SS**  trans-82.753.9165.8-105.373.5000112.8
424W43.3Very low38.4Very low223 Ų223155.8 Ų155.885%0.84581%0.811SS**  trans-93.3-18.4-176.5-160.9-77.8000115.1G422G422-W424 VanDerWaalsContact C-N 3.34Å; G422-W424 PolarHBondContact O-N 3.2Å
425H38.1Very low39.6Very low171 Ų171151.8 Ų151.879%0.79279%0.787SS**SBendtrans-130.585.3-179.1-70.4-77.3000112.1
426K37.1Very low41.9Very low197 Ų197146.7 Ų146.786%0.85776%0.757SS**  trans-15997.3147.3-104173.9-169-171.60107.3K428K426-K428 PolarHBondContact O-N 3.09Å
427N33.4Very low44.8Very low166 Ų166142 Ų14289%0.88872%0.719SS**  trans-54.4123.2166.3-78.4-19.3000107.8T429N427-T429 PolarHBondContact O-N 3.33Å; N427-T429 VanDerWaalsContact O-N 3.17Å
428K36.2Very low47.5Very low206 Ų206136.5 Ų136.590%0.89668%0.683SS**  trans-63.3112.2177.1-70.6177.8176.4179.60108.9K426K426-K428 PolarHBondContact O-N 3.09Å
429T32Very low50.4Low120 Ų120132.3 Ų132.374%0.73665%0.654SS**  trans-72.1126.6156.322.70000108.2N427 G431N427-T429 PolarHBondContact O-N 3.33Å; N427-T429 VanDerWaalsContact O-N 3.17Å; T429-G431 PolarHBondContact O-N 2.69Å
430P35.8Very low53.2Low136 Ų136127.3 Ų127.388%0.88361%0.612SS**THydrogen-bonded Turntrans-73.4109.3170.424-19.8000108
431G38Very low56Low65 Ų65116.7 Ų116.767%0.6757%0.572SS**THydrogen-bonded Turntrans168.3-24.5179.200000116.6T429 Y433T429-G431 PolarHBondContact O-N 2.69Å; G431-Y433 PolarHBondContact O-N 2.92Å
432E41.4Very low59.1Low155 Ų155106 Ų10672%0.72453%0.53SS*.  trans-86.489170.8-80.6-179.5175.600109.5R434E432-R434 VanDerWaalsContact C-N 3.26Å; E432-R434 PolarHBondContact O-N 2.98Å
433Y46.8Very low62.1Low215 Ų215102.6 Ų102.684%0.84350%0.495SS*.  trans-59.698.9154.6-78.2-88.5000106.5G431 T435G431-Y433 PolarHBondContact O-N 2.92Å; Y433-T435 PolarHBondContact O-N 3.31Å
434R53.3Low65Low216 Ų21693.2 Ų93.282%0.81545%0.451SS*.  trans-70.386.4170.3-73.8-173.8-177173.60107.4E432E432-R434 VanDerWaalsContact C-N 3.26Å; E432-R434 PolarHBondContact O-N 2.98Å
435T63.3Low67.5Low54 Ų5482.6 Ų82.633%0.33141%0.411SS..  trans-71.4126.2165.6490000106.6Y433 R438 E466Y433-T435 PolarHBondContact O-N 3.31Å; T435-R438 PolarHBondContact OG1-NH2 3.4Å; T435-E466 WeakPolarHBondContact CB-OE2 3.29Å; T435-E466 WeakPolarHBondContact CG2-OE2 3.29Å
436G82.3Confident70.3Confident11 Ų1174.5 Ų74.511%0.11337%0.373CS..  trans-68.7-156.9176.300000111.1K464G436-K464 VanDerWaalsContact CA-O 3.3Å; G436-K464 WeakPolarHBondContact CA-O 3.47Å
437P94.3Very high73.2Confident0 Ų065.1 Ų65.10%033%0.333CS..SBendtrans-59.2146.1176.9-16.227.5000111.5D126 R129 W465 E466D126-P437 HydrophobicContact CB-CG 4.21Å; D126-P437 WeakPolarHBondContact O-CA 3.32Å; D126-P437 WeakPolarHBondContact O-CB 3.31Å; R129-P437 HydrophobicContact CB-CB 3.91Å; R129-P437 HydrophobicContact CB-CG 4.11Å; R129-P437 VanDerWaalsContact NH1-CG 3.34Å; P437-W465 HydrophobicContact CB-CD2 3.71Å; P437-W465 HydrophobicContact CB-CE3 3.62Å; P437-W465 HydrophobicContact CB-CG 4.46Å; P437-W465 HydrophobicContact CB-CH2 3.86Å; P437-W465 HydrophobicContact CB-CZ2 3.97Å; P437-W465 HydrophobicContact CB-CZ3 3.68Å; P437-W465 HydrophobicContact CG-CD2 4.19Å; P437-W465 HydrophobicContact CG-CZ2 4.3Å; P437-W465 WeakPolarHBondContact O-CA 3.3Å; P437-E466 PolarHBondContact O-N 3.02Å
438R96.9Very high76.3Confident23 Ų2357.5 Ų57.59%0.08729%0.293CS..EExtended strand (participates in β ladder)trans-106134.5-178.9-70.3-177.6167.5-176.4-13112.2L85 E87 S130 Q131 T435 E466L85-R438 VanDerWaalsContact CB-NH1 3.33Å; E87-R438 WeakPolarHBondContact OE1-CD 3.37Å; S130-R438 CarbonylContact C-O 3.53Å; S130-R438 WeakPolarHBondContact CA-O 3.42Å; S130-R438 WeakPolarHBondContact CB-O 3.41Å; S130-R438 PolarHBondContact OG-N 2.87Å; S130-R438 VanDerWaalsContact OG-N 3.13Å; Q131-R438 PolarHBondContact N-O 3.29Å; T435-R438 PolarHBondContact OG1-NH2 3.4Å; R438-E466 CarbonylContact C-O 3.6Å; R438-E466 VanDerWaalsContact CA-O 3.31Å; R438-E466 WeakPolarHBondContact CA-O 3.42Å; R438-E466 HydrophobicContact CG-CB 4.27Å; R438-E466 IonicContact CZ-OE2 2.88Å; R438-E466 IonicContact NE-OE2 2.69Å; R438-E466 PolarHBondContact NE-OE2 3.42Å; R438-E466 IonicContact NH2-OE1 3.85Å; R438-E466 IonicContact NH2-OE2 3.26Å; R438-E466 PolarHBondContact NH2-OE2 2.93Å
439L98.4Very high79.3Confident0 Ų048.3 Ų48.30%025%0.253CS..EExtended strand (participates in β ladder)trans-106.4106.7166177.366.9000108.5Q131 I133 M388 A391 I392 V441 W465 E466 A467 I468Q131-L439 HydrophobicContact CB-CD1 3.83Å; I133-L439 HydrophobicContact CD1-CD1 3.77Å; I133-L439 HydrophobicContact CG1-CD1 4.05Å; M388-L439 HydrophobicContact CB-CD2 3.78Å; M388-L439 HydrophobicContact CG-CD2 3.83Å; M388-L439 WeakPolarHBondContact O-CD2 3.4Å; A391-L439 HydrophobicContact CB-CD1 3.87Å; A391-L439 HydrophobicContact CB-CD2 3.96Å; I392-L439 HydrophobicContact CD1-CD2 4.24Å; I392-L439 HydrophobicContact CG1-CB 4.42Å; I392-L439 HydrophobicContact CG1-CD2 4.07Å; L439-V441 HydrophobicContact CG-CG2 4.42Å; L439-W465 HydrophobicContact CB-CE3 4.22Å; L439-W465 HydrophobicContact CB-CZ3 4.44Å; L439-E466 PolarHBondContact N-O 3.42Å; L439-A467 CarbonylContact O-C 3.58Å; L439-A467 VanDerWaalsContact O-CA 3.3Å; L439-A467 WeakPolarHBondContact O-CA 3.29Å; L439-I468 PolarHBondContact O-N 3Å
440M98.7Very high82.5Confident0 Ų042.7 Ų42.70%022%0.219CC..EExtended strand (participates in β ladder)trans-94.6136174.7-66.8164.5-78.200109.7E87 P89 Q131 L132 I133 I468E87-M440 HydrophobicContact CB-CE 3.97Å; E87-M440 HydrophobicContact CG-CE 4.22Å; P89-M440 HydrophobicContact CB-CE 3.47Å; P89-M440 VanDerWaalsContact CB-CE 3.47Å; P89-M440 HydrophobicContact CG-CE 3.51Å; Q131-M440 PolarHBondContact O-N 3.04Å; L132-M440 CarbonylContact C-O 3.57Å; L132-M440 VanDerWaalsContact CA-O 3.29Å; L132-M440 WeakPolarHBondContact CA-O 3.38Å; L132-M440 HydrophobicContact CB-CB 4.37Å; L132-M440 HydrophobicContact CD1-CB 3.61Å; I133-M440 PolarHBondContact N-O 3.37Å; M440-I468 CarbonylContact C-O 3.53Å; M440-I468 VanDerWaalsContact CA-O 3.31Å; M440-I468 WeakPolarHBondContact CA-O 3.23Å; M440-I468 HydrophobicContact CG-CB 4.29Å
441V98.8Very high85.5Confident0 Ų036.2 Ų36.20%018%0.177CC..EExtended strand (participates in β ladder)trans-124.7130177173.20000108.6Y47 I133 L135 I384 M388 L439 I443 I468 I469 G470Y47-V441 PolarHBondContact OH-O 3.26Å; I133-V441 WeakPolarHBondContact O-CA 3.2Å; L135-V441 HydrophobicContact CD1-CG1 3.9Å; I384-V441 HydrophobicContact CD1-CG1 3.66Å; I384-V441 HydrophobicContact CD1-CG2 4.27Å; I384-V441 HydrophobicContact CG1-CG1 4.3Å; M388-V441 HydrophobicContact CE-CB 4.14Å; M388-V441 HydrophobicContact CE-CG2 3.72Å; M388-V441 HydrophobicContact CG-CG2 4.13Å; L439-V441 HydrophobicContact CG-CG2 4.42Å; V441-I443 HydrophobicContact CG1-CG1 4.23Å; V441-I468 PolarHBondContact N-O 2.68Å; V441-I469 HydrophobicContact CB-CG1 4.24Å; V441-I469 HydrophobicContact CG1-CG1 4.17Å; V441-I469 CarbonylContact O-C 3.49Å; V441-I469 WeakPolarHBondContact O-CA 3.49Å; V441-G470 PolarHBondContact O-N 3.44Å
442F98.9Very high88.4Confident0 Ų033.1 Ų33.10%015%0.145CC..EExtended strand (participates in β ladder)trans-120.1124.1171.9-175.8-112.2000111.3Y47 L49 L74 L78 L103 I133 I134 L135 I444 G470 S471 T472Y47-F442 AromaticContact CE2-CD2 3.93Å; Y47-F442 HydrophobicContact CE2-CD2 3.93Å; Y47-F442 HydrophobicContact CE2-CE2 4.46Å; Y47-F442 WeakPolarHBondContact OH-CB 3.38Å; L49-F442 HydrophobicContact CD1-CD2 4.37Å; L49-F442 HydrophobicContact CD1-CE2 3.38Å; L49-F442 HydrophobicContact CD1-CZ 3.54Å; L49-F442 HydrophobicContact CG-CE2 3.85Å; L49-F442 HydrophobicContact CG-CZ 4.4Å; L74-F442 HydrophobicContact CD1-CE1 4.36Å; L74-F442 HydrophobicContact CD1-CZ 4.28Å; L78-F442 HydrophobicContact CD1-CB 4.37Å; L78-F442 HydrophobicContact CD1-CD1 3.7Å; L78-F442 HydrophobicContact CD1-CD2 4.36Å; L78-F442 HydrophobicContact CD1-CE1 4Å; L78-F442 HydrophobicContact CD1-CG 3.87Å; L78-F442 HydrophobicContact CD1-CZ 4.44Å; L78-F442 HydrophobicContact CD2-CB 4.07Å; L78-F442 HydrophobicContact CD2-CD1 4.4Å; L78-F442 HydrophobicContact CD2-CD2 3.6Å; L78-F442 HydrophobicContact CD2-CE2 4.07Å; L78-F442 HydrophobicContact CD2-CG 3.76Å; L78-F442 HydrophobicContact CG-CD2 4.44Å; L78-F442 HydrophobicContact CG-CG 4.4Å; L103-F442 HydrophobicContact CD2-CD1 4.06Å; L103-F442 HydrophobicContact CD2-CE1 3.81Å; I133-F442 PolarHBondContact O-N 3.21Å; I134-F442 WeakPolarHBondContact CA-O 3.26Å; I134-F442 HydrophobicContact CG2-CD1 4.49Å; L135-F442 PolarHBondContact N-O 2.73Å; F442-I444 HydrophobicContact CD1-CG1 4.23Å; F442-I444 HydrophobicContact CE1-CG1 3.85Å; F442-G470 CarbonylContact C-O 3.51Å; F442-G470 WeakPolarHBondContact CA-O 3.43Å; F442-S471 VanDerWaalsContact CE2-C 3.41Å; F442-T472 HydrophobicContact CZ-CG2 3.86Å
443I98.9Very high91.1Very high0 Ų026.6 Ų26.60%011%0.113CC..EExtended strand (participates in β ladder)trans-106.4120.8175-54166.7000109.3L135 F139 V441 G445 G446 A447 I469 G470 S471L135-I443 HydrophobicContact CB-CG1 4.28Å; L135-I443 HydrophobicContact CD1-CG1 4.26Å; L135-I443 CarbonylContact O-C 3.23Å; L135-I443 WeakPolarHBondContact O-CA 3.23Å; F139-I443 HydrophobicContact CE1-CD1 3.88Å; F139-I443 HydrophobicContact CE1-CG1 4.14Å; F139-I443 HydrophobicContact CE1-CG2 4.07Å; F139-I443 HydrophobicContact CZ-CD1 4.03Å; V441-I443 HydrophobicContact CG1-CG1 4.23Å; I443-G445 PolarHBondContact O-N 3.24Å; I443-G446 WeakPolarHBondContact CG2-O 3.47Å; I443-A447 HydrophobicContact CD1-CB 4.25Å; I443-I469 HydrophobicContact CD1-CD1 4.11Å; I443-G470 PolarHBondContact N-O 3.38Å; I443-S471 VanDerWaalsContact O-CA 3.26Å; I443-S471 WeakPolarHBondContact O-CA 3.08Å; I443-S471 WeakPolarHBondContact O-CB 3.45Å; I443-S471 PolarHBondContact O-OG 3.29Å; I443-S471 VanDerWaalsContact O-OG 3.12Å
444I98.3Very high93.6Very high0 Ų016.3 Ų16.30%07%0.073CC..EExtended strand (participates in β ladder)trans-73.6123.6171.7-54.7170.2000107.9F58 Y59 N100 L103 I134 L135 R137 F442F58-I444 HydrophobicContact CB-CG2 4.27Å; F58-I444 HydrophobicContact CD1-CD1 4.47Å; F58-I444 HydrophobicContact CD1-CG2 3.67Å; F58-I444 HydrophobicContact CD2-CG2 3.79Å; F58-I444 HydrophobicContact CE1-CD1 3.92Å; F58-I444 HydrophobicContact CE1-CG2 3.79Å; F58-I444 HydrophobicContact CE2-CG2 3.89Å; F58-I444 HydrophobicContact CG-CG2 3.63Å; F58-I444 HydrophobicContact CZ-CD1 4.37Å; F58-I444 HydrophobicContact CZ-CG2 3.86Å; Y59-I444 PolarHBondContact OH-O 3Å; Y59-I444 VanDerWaalsContact OH-O 3.09Å; N100-I444 WeakPolarHBondContact OD1-CD1 3.39Å; L103-I444 HydrophobicContact CD2-CD1 3.68Å; L103-I444 HydrophobicContact CD2-CG1 3.86Å; I134-I444 HydrophobicContact CG2-CD1 4.26Å; L135-I444 PolarHBondContact O-N 3.34Å; R137-I444 WeakPolarHBondContact CB-O 3.37Å; R137-I444 PolarHBondContact N-O 3.34Å; R137-I444 VanDerWaalsContact N-O 3.09Å; F442-I444 HydrophobicContact CD1-CG1 4.23Å; F442-I444 HydrophobicContact CE1-CG1 3.85Å
445G96.1Very high95.7Very high0 Ų06 Ų60%03%0.034CC..THydrogen-bonded Turntrans89.828.9173.400000115.5F55 I443 T472F55-G445 WeakPolarHBondContact CD2-O 3.28Å; I443-G445 PolarHBondContact O-N 3.24Å; G445-T472 PolarHBondContact N-OG1 2.87Å
446G97.6Very high97.4Very high0 Ų04 Ų40%02%0.02CC..  trans108.3141.616700000114.5R137 I443 S471 H473 F475R137-G446 VanDerWaalsContact CD-O 3.3Å; R137-G446 WeakPolarHBondContact CD-O 3.28Å; R137-G446 PolarHBondContact NH1-O 2.98Å; I443-G446 WeakPolarHBondContact CG2-O 3.47Å; G446-S471 WeakPolarHBondContact CA-OG 3.33Å; G446-S471 PolarHBondContact N-OG 2.91Å; G446-H473 VanDerWaalsContact CA-O 3.28Å; G446-H473 WeakPolarHBondContact CA-O 3.34Å; G446-F475 VanDerWaalsContact CA-CD1 3.46Å; G446-F475 VanDerWaalsContact CA-CE1 3.41Å; G446-F475 WeakPolarHBondContact O-CE1 3.28Å
447A98.4Very high98.1Very high0 Ų06.3 Ų6.30%03%0.028CC..EExtended strand (participates in β ladder)trans-114.8141.417100000109.8I443 S471 H473 I474 F475I443-A447 HydrophobicContact CD1-CB 4.25Å; A447-S471 PolarHBondContact N-OG 2.89Å; A447-S471 VanDerWaalsContact N-OG 3.16Å; A447-H473 PolarHBondContact N-O 3.19Å; A447-H473 VanDerWaalsContact N-O 3.12Å; A447-I474 HydrophobicContact CB-CD1 4.17Å; A447-F475 PolarHBondContact O-N 2.94Å
448S98.6Very high98.2Very high7 Ų76.5 Ų6.55%0.0493%0.03CC..EExtended strand (participates in β ladder)trans-87.7159.2174.478.10000111.7S450 E451 M452S448-S450 VanDerWaalsContact C-N 3.26Å; S448-S450 PolarHBondContact O-N 3.37Å; S448-S450 PolarHBondContact OG-OG 3.41Å; S448-E451 PolarHBondContact N-OE2 3.28Å; S448-E451 WeakPolarHBondContact O-CB 3.41Å; S448-E451 PolarHBondContact O-N 2.87Å; S448-E451 VanDerWaalsContact O-N 3.16Å; S448-E451 WeakPolarHBondContact OG-CG 2.98Å; S448-E451 PolarHBondContact OG-N 3.39Å; S448-M452 WeakPolarHBondContact O-CG 3.33Å; S448-M452 PolarHBondContact O-N 3.34Å
449F98.8Very high98.2Very high12 Ų126.6 Ų6.65%0.0533%0.033CC..Hα-helixtrans-62.7-29176.1-70.6-76.1000113.8Y42 Q152 A153 Y156 M452 R453 I474 T476Y42-F449 HydrophobicContact CE1-CE1 4.31Å; Q152-F449 VanDerWaalsContact CD-CD1 3.47Å; Q152-F449 HydrophobicContact CG-CD1 3.5Å; Q152-F449 VanDerWaalsContact CG-CD1 3.5Å; Q152-F449 HydrophobicContact CG-CE1 3.85Å; Q152-F449 HydrophobicContact CG-CG 4.2Å; A153-F449 HydrophobicContact CB-CB 3.61Å; Y156-F449 HydrophobicContact CD1-CE1 4.33Å; Y156-F449 AromaticContact CD1-CE2 3.69Å; Y156-F449 HydrophobicContact CD1-CE2 3.69Å; Y156-F449 AromaticContact CD1-CZ 3.38Å; Y156-F449 HydrophobicContact CD1-CZ 3.38Å; Y156-F449 HydrophobicContact CD2-CE1 4.43Å; Y156-F449 HydrophobicContact CD2-CE2 4.46Å; Y156-F449 HydrophobicContact CD2-CZ 4.12Å; Y156-F449 HydrophobicContact CE1-CE1 4.42Å; Y156-F449 HydrophobicContact CE1-CE2 4.49Å; Y156-F449 AromaticContact CE1-CZ 3.73Å; Y156-F449 HydrophobicContact CE1-CZ 3.73Å; Y156-F449 HydrophobicContact CE2-CZ 4.43Å; Y156-F449 HydrophobicContact CG-CD2 4.43Å; Y156-F449 HydrophobicContact CG-CE1 4.31Å; Y156-F449 AromaticContact CG-CE2 3.66Å; Y156-F449 HydrophobicContact CG-CE2 3.66Å; Y156-F449 AromaticContact CG-CZ 3.58Å; Y156-F449 HydrophobicContact CG-CZ 3.58Å; F449-M452 HydrophobicContact CD1-CE 3.72Å; F449-M452 HydrophobicContact CD1-SD 3.68Å; F449-M452 HydrophobicContact CE1-CE 3.98Å; F449-M452 HydrophobicContact CE1-SD 4.11Å; F449-M452 HydrophobicContact CG-SD 4.32Å; F449-M452 PolarHBondContact O-N 2.82Å; F449-R453 PolarHBondContact O-N 3.49Å; F449-I474 HydrophobicContact CD1-CG2 4.42Å; F449-I474 HydrophobicContact CE1-CG2 3.93Å; F449-I474 HydrophobicContact CE2-CG2 4.03Å; F449-I474 HydrophobicContact CZ-CG2 3.71Å; F449-T476 HydrophobicContact CE2-CG2 4.19Å
450S98.6Very high98Very high3 Ų313.7 Ų13.72%0.0217%0.066CC..Hα-helixtrans-71.6-33.517554.90000112.6E148 S448 R453 C454E148-S450 VanDerWaalsContact CD-CB 3.41Å; E148-S450 WeakPolarHBondContact OE1-CB 3.43Å; S448-S450 VanDerWaalsContact C-N 3.26Å; S448-S450 PolarHBondContact O-N 3.37Å; S448-S450 PolarHBondContact OG-OG 3.41Å; S450-R453 WeakPolarHBondContact O-CB 3.27Å; S450-C454 PolarHBondContact O-N 3.02Å; S450-C454 PolarHBondContact O-SG 3.42Å
451E98.8Very high97.8Very high0 Ų017.9 Ų17.90%010%0.1CC..Hα-helixtrans-69.9-40.7172.5-67.1174.7142.500111.6R137 F139 P382 I384 S448 R453 C454 I469R137-E451 IonicContact CZ-OE1 3.53Å; R137-E451 IonicContact CZ-OE2 2.84Å; R137-E451 IonicContact NH1-OE1 3.13Å; R137-E451 PolarHBondContact NH1-OE1 3.49Å; R137-E451 IonicContact NH1-OE2 2.71Å; R137-E451 PolarHBondContact NH1-OE2 3.48Å; R137-E451 IonicContact NH2-OE1 2.78Å; R137-E451 PolarHBondContact NH2-OE1 3.29Å; R137-E451 IonicContact NH2-OE2 3.8Å; F139-E451 VanDerWaalsContact CZ-OE1 3.23Å; F139-E451 WeakPolarHBondContact CZ-OE1 3.3Å; P382-E451 HydrophobicContact CB-CG 4.11Å; I384-E451 HydrophobicContact CG2-CB 3.85Å; I384-E451 HydrophobicContact CG2-CG 3.79Å; S448-E451 PolarHBondContact N-OE2 3.28Å; S448-E451 WeakPolarHBondContact O-CB 3.41Å; S448-E451 PolarHBondContact O-N 2.87Å; S448-E451 VanDerWaalsContact O-N 3.16Å; S448-E451 WeakPolarHBondContact OG-CG 2.98Å; S448-E451 PolarHBondContact OG-N 3.39Å; E451-R453 VanDerWaalsContact C-N 3.34Å; E451-R453 PolarHBondContact O-N 3.3Å; E451-C454 WeakPolarHBondContact O-CB 3.41Å; E451-C454 PolarHBondContact O-N 3.05Å; E451-C454 VanDerWaalsContact O-N 3.14Å; E451-I469 HydrophobicContact CB-CD1 3.97Å
452M98.8Very high97.5Very high0 Ų020.8 Ų20.80%012%0.116CC..Hα-helixtrans-56-48.8172.6-69.6164.352.200111.4Y42 E43 V46 S448 F449 C454 A455 Y456 I469 I474Y42-M452 HydrophobicContact CD1-CE 3.93Å; Y42-M452 HydrophobicContact CE1-CE 3.69Å; E43-M452 HydrophobicContact CG-CE 4.25Å; V46-M452 HydrophobicContact CB-CE 4.35Å; V46-M452 HydrophobicContact CG1-CE 4.05Å; V46-M452 HydrophobicContact CG1-CG 3.9Å; V46-M452 HydrophobicContact CG1-SD 4.17Å; V46-M452 HydrophobicContact CG2-CB 3.97Å; V46-M452 HydrophobicContact CG2-CE 3.93Å; V46-M452 HydrophobicContact CG2-CG 3.9Å; S448-M452 WeakPolarHBondContact O-CG 3.33Å; S448-M452 PolarHBondContact O-N 3.34Å; F449-M452 HydrophobicContact CD1-CE 3.72Å; F449-M452 HydrophobicContact CD1-SD 3.68Å; F449-M452 HydrophobicContact CE1-CE 3.98Å; F449-M452 HydrophobicContact CE1-SD 4.11Å; F449-M452 HydrophobicContact CG-SD 4.32Å; F449-M452 PolarHBondContact O-N 2.82Å; M452-C454 PolarHBondContact O-N 2.9Å; M452-A455 WeakPolarHBondContact O-CB 3.38Å; M452-A455 PolarHBondContact O-N 3.36Å; M452-A455 VanDerWaalsContact O-N 3.09Å; M452-Y456 WeakPolarHBondContact O-CD2 3.47Å; M452-I469 HydrophobicContact CG-CG2 4.46Å; M452-I474 HydrophobicContact SD-CD1 3.91Å; M452-I474 HydrophobicContact SD-CG1 4.32Å; M452-I474 HydrophobicContact SD-CG2 3.68Å
453R98.7Very high96.8Very high17 Ų1724.2 Ų24.26%0.06415%0.151CC..Hα-helixtrans-52.7-40.7175.8-176.1-175.773-131-3.5112.4E148 T150 H195 F449 S450 E451 A455 Y456 E457E148-R453 IonicContact OE1-NH2 3.21Å; E148-R453 IonicContact OE2-CZ 2.78Å; E148-R453 IonicContact OE2-NH1 3.15Å; E148-R453 PolarHBondContact OE2-NH1 3.2Å; E148-R453 IonicContact OE2-NH2 2.66Å; T150-R453 PolarHBondContact OG1-NH1 3.23Å; H195-R453 HydrophobicContact CB-CG 3.9Å; F449-R453 PolarHBondContact O-N 3.49Å; S450-R453 WeakPolarHBondContact O-CB 3.27Å; E451-R453 VanDerWaalsContact C-N 3.34Å; E451-R453 PolarHBondContact O-N 3.3Å; R453-A455 VanDerWaalsContact C-N 3.27Å; R453-A455 PolarHBondContact O-N 3.15Å; R453-Y456 PolarHBondContact O-N 2.9Å; R453-Y456 VanDerWaalsContact O-N 3.13Å; R453-E457 VanDerWaalsContact CD-OE1 3.25Å; R453-E457 WeakPolarHBondContact CD-OE1 3.44Å; R453-E457 HydrophobicContact CG-CG 4.25Å; R453-E457 WeakPolarHBondContact CG-OE1 2.81Å; R453-E457 IonicContact NE-OE1 3.99Å; R453-E457 PolarHBondContact NE-OE1 2.82Å; R453-E457 WeakPolarHBondContact O-CG 3.49Å; R453-E457 PolarHBondContact O-N 3.35Å
454C98.6Very high96.5Very high0 Ų029.3 Ų29.30%017%0.173CC..Hα-helixtrans-60.9-34.1-178.8-66.40000112.7I384 K385 S450 E451 M452 Y456 E457 V458I384-C454 HydrophobicContact CG2-CB 4.07Å; K385-C454 HydrophobicContact CB-CB 4Å; K385-C454 HydrophobicContact CG-CB 4.29Å; S450-C454 PolarHBondContact O-N 3.02Å; S450-C454 PolarHBondContact O-SG 3.42Å; E451-C454 WeakPolarHBondContact O-CB 3.41Å; E451-C454 PolarHBondContact O-N 3.05Å; E451-C454 VanDerWaalsContact O-N 3.14Å; M452-C454 PolarHBondContact O-N 2.9Å; C454-Y456 VanDerWaalsContact C-N 3.33Å; C454-Y456 PolarHBondContact O-N 2.93Å; C454-E457 PolarHBondContact O-N 3.03Å; C454-V458 WeakPolarHBondContact O-CB 3.44Å; C454-V458 VanDerWaalsContact O-CG2 3.25Å; C454-V458 WeakPolarHBondContact O-CG2 3.3Å; C454-V458 PolarHBondContact O-N 3.29Å
455A98.5Very high96.4Very high0 Ų029.8 Ų29.80%018%0.175CC..Hα-helixtrans-61.5-41.617600000111.8Q45 M388 M452 R453 T459 A467 I469Q45-A455 PolarHBondContact NE2-O 3.26Å; Q45-A455 VanDerWaalsContact NE2-O 3.17Å; M388-A455 HydrophobicContact CE-CB 4Å; M388-A455 HydrophobicContact SD-CB 4.42Å; M452-A455 WeakPolarHBondContact O-CB 3.38Å; M452-A455 PolarHBondContact O-N 3.36Å; M452-A455 VanDerWaalsContact O-N 3.09Å; R453-A455 VanDerWaalsContact C-N 3.27Å; R453-A455 PolarHBondContact O-N 3.15Å; A455-T459 WeakPolarHBondContact O-CB 3.32Å; A455-T459 PolarHBondContact O-N 3.45Å; A455-T459 VanDerWaalsContact O-N 3.08Å; A455-T459 PolarHBondContact O-OG1 3.03Å; A455-A467 HydrophobicContact CB-CB 4.27Å; A455-I469 HydrophobicContact CB-CB 4.17Å; A455-I469 HydrophobicContact CB-CG2 3.7Å
456Y98.4Very high96.4Very high11 Ų1131.3 Ų31.34%0.04318%0.182CC..Hα-helixtrans-68.4-45.6175.6-64.9-85.9000112.1E43 S44 Q45 V46 R194 H195 M452 R453 C454 V458 T459 Q460E43-Y456 WeakPolarHBondContact CB-OH 3.23Å; E43-Y456 WeakPolarHBondContact OE2-CE2 3.24Å; E43-Y456 PolarHBondContact OE2-OH 3.04Å; S44-Y456 PolarHBondContact OG-OH 3.23Å; Q45-Y456 HydrophobicContact CB-CD1 4.31Å; Q45-Y456 HydrophobicContact CB-CE1 3.72Å; Q45-Y456 HydrophobicContact CB-CE2 4.24Å; Q45-Y456 HydrophobicContact CG-CD1 4.19Å; Q45-Y456 HydrophobicContact CG-CE1 3.79Å; Q45-Y456 PolarHBondContact N-OH 3.18Å; V46-Y456 HydrophobicContact CG2-CE2 4Å; R194-Y456 VanDerWaalsContact NH2-CE1 3.3Å; R194-Y456 PolarHBondContact NH2-OH 2.77Å; H195-Y456 AromaticContact CD2-CD2 3.76Å; H195-Y456 AromaticContact CD2-CG 3.82Å; H195-Y456 AromaticContact CE1-CD2 3.88Å; H195-Y456 AromaticContact CE1-CE2 3.99Å; H195-Y456 AromaticContact NE2-CD2 3.07Å; H195-Y456 WeakPolarHBondContact NE2-CD2 3.1Å; H195-Y456 AromaticContact NE2-CE2 3.31Å; H195-Y456 VanDerWaalsContact NE2-CE2 3.31Å; H195-Y456 WeakPolarHBondContact NE2-CE2 3.32Å; H195-Y456 AromaticContact NE2-CG 3.56Å; H195-Y456 AromaticContact NE2-CZ 3.99Å; M452-Y456 WeakPolarHBondContact O-CD2 3.47Å; R453-Y456 PolarHBondContact O-N 2.9Å; R453-Y456 VanDerWaalsContact O-N 3.13Å; C454-Y456 VanDerWaalsContact C-N 3.33Å; C454-Y456 PolarHBondContact O-N 2.93Å; Y456-V458 VanDerWaalsContact C-N 3.3Å; Y456-V458 PolarHBondContact O-N 3.13Å; Y456-T459 PolarHBondContact O-N 3.1Å; Y456-Q460 WeakPolarHBondContact O-CB 3.46Å; Y456-Q460 VanDerWaalsContact O-CG 3.26Å; Y456-Q460 WeakPolarHBondContact O-CG 3.42Å; Y456-Q460 PolarHBondContact O-N 3.43Å
457E97.3Very high96.4Very high59 Ų5931.3 Ų31.328%0.27618%0.182SC..Hα-helixtrans-58.5-43.5178.7-69.7175-175.600111.5K385 R453 C454 A461K385-E457 WeakPolarHBondContact CE-OE2 3.36Å; K385-E457 IonicContact NZ-OE2 3.3Å; K385-E457 PolarHBondContact NZ-OE2 3Å; R453-E457 VanDerWaalsContact CD-OE1 3.25Å; R453-E457 WeakPolarHBondContact CD-OE1 3.44Å; R453-E457 HydrophobicContact CG-CG 4.25Å; R453-E457 WeakPolarHBondContact CG-OE1 2.81Å; R453-E457 IonicContact NE-OE1 3.99Å; R453-E457 PolarHBondContact NE-OE1 2.82Å; R453-E457 WeakPolarHBondContact O-CG 3.49Å; R453-E457 PolarHBondContact O-N 3.35Å; C454-E457 PolarHBondContact O-N 3.03Å; E457-A461 VanDerWaalsContact O-CB 3.23Å; E457-A461 WeakPolarHBondContact O-CB 3.26Å; E457-A461 PolarHBondContact O-N 3.31Å
458V96.8Very high96.4Very high5 Ų531.9 Ų31.93%0.0319%0.185CC..Hα-helixtrans-68.2-44.6179.2171.80000111.5K385 M388 E389 I392 C454 Y456 Q460 A461 N462 A467K385-V458 HydrophobicContact CG-CG2 3.83Å; M388-V458 HydrophobicContact CB-CG1 4.25Å; M388-V458 HydrophobicContact CB-CG2 4.16Å; M388-V458 HydrophobicContact SD-CG2 4.45Å; E389-V458 HydrophobicContact CG-CG1 4.48Å; E389-V458 HydrophobicContact CG-CG2 3.99Å; I392-V458 HydrophobicContact CD1-CG1 3.36Å; C454-V458 WeakPolarHBondContact O-CB 3.44Å; C454-V458 VanDerWaalsContact O-CG2 3.25Å; C454-V458 WeakPolarHBondContact O-CG2 3.3Å; C454-V458 PolarHBondContact O-N 3.29Å; Y456-V458 VanDerWaalsContact C-N 3.3Å; Y456-V458 PolarHBondContact O-N 3.13Å; V458-Q460 PolarHBondContact O-N 2.91Å; V458-A461 PolarHBondContact O-N 2.87Å; V458-N462 WeakPolarHBondContact O-CB 3.35Å; V458-N462 PolarHBondContact O-N 3.13Å; V458-A467 HydrophobicContact CG1-CB 4.47Å
459T96.5Very high96.5Very high25 Ų2531.6 Ų31.615%0.15318%0.183CC..Hα-helixtrans-59-47.1175.7-67.20000111.3Q45 A455 Y456 G463 A467Q45-T459 PolarHBondContact NE2-OG1 3.24Å; A455-T459 WeakPolarHBondContact O-CB 3.32Å; A455-T459 PolarHBondContact O-N 3.45Å; A455-T459 VanDerWaalsContact O-N 3.08Å; A455-T459 PolarHBondContact O-OG1 3.03Å; Y456-T459 PolarHBondContact O-N 3.1Å; T459-G463 PolarHBondContact O-N 3.33Å; T459-A467 PolarHBondContact OG1-N 2.91Å
460Q94.8Very high96.5Very high148 Ų14831 Ų3169%0.69218%0.18SC*.Hα-helixtrans-65.9-41.9-179.7-7117729.700112.3Y456 V458Y456-Q460 WeakPolarHBondContact O-CB 3.46Å; Y456-Q460 VanDerWaalsContact O-CG 3.26Å; Y456-Q460 WeakPolarHBondContact O-CG 3.42Å; Y456-Q460 PolarHBondContact O-N 3.43Å; V458-Q460 PolarHBondContact O-N 2.91Å
461A93Very high96.5Very high88 Ų8830.9 Ų30.973%0.72718%0.179SC*.Hα-helixtrans-69.4-36.2-179.800000112.7E457 V458E457-A461 VanDerWaalsContact O-CB 3.23Å; E457-A461 WeakPolarHBondContact O-CB 3.26Å; E457-A461 PolarHBondContact O-N 3.31Å; V458-A461 PolarHBondContact O-N 2.87Å
462N92.4Very high96.4Very high62 Ų6230.9 Ų30.933%0.33218%0.179SC..Hα-helixtrans-80.1-39.8-179.6-171.8-87.8000112.9I392 V458 K464 W465I392-N462 VanDerWaalsContact CG2-ND2 3.34Å; I392-N462 WeakPolarHBondContact CG2-ND2 3.36Å; V458-N462 WeakPolarHBondContact O-CB 3.35Å; V458-N462 PolarHBondContact O-N 3.13Å; N462-K464 PolarHBondContact O-N 3.37Å; N462-K464 PolarHBondContact OD1-N 3.23Å; N462-W465 VanDerWaalsContact OD1-CD1 3.28Å; N462-W465 PolarHBondContact OD1-N 2.85Å
463G85.1Confident96.4Very high71 Ų7131.6 Ų31.673%0.73218%0.183SC*.SBendtrans71.3-10.6178.400000116.1T459T459-G463 PolarHBondContact O-N 3.33Å
464K92.1Very high96.4Very high108 Ų10832.3 Ų32.347%0.4719%0.188SC..SBendtrans-112.7-47.5175.4-176.3-179.5179.9178.60112.7D126 G436 N462D126-K464 WeakPolarHBondContact OD1-CE 3.32Å; D126-K464 IonicContact OD1-NZ 3.74Å; G436-K464 VanDerWaalsContact CA-O 3.3Å; G436-K464 WeakPolarHBondContact CA-O 3.47Å; N462-K464 PolarHBondContact O-N 3.37Å; N462-K464 PolarHBondContact OD1-N 3.23Å
465W95.7Very high96.2Very high9 Ų932.6 Ų32.63%0.03419%0.189CC..  trans-81145.8179.2-7578000111.2R129 I392 P437 L439 N462R129-W465 HydrophobicContact CB-CH2 4.24Å; R129-W465 HydrophobicContact CB-CZ2 4.46Å; R129-W465 WeakPolarHBondContact O-CH2 3.29Å; I392-W465 HydrophobicContact CB-CD2 4.39Å; I392-W465 HydrophobicContact CB-CG 4.46Å; I392-W465 HydrophobicContact CD1-CB 3.94Å; I392-W465 HydrophobicContact CD1-CG 4.32Å; I392-W465 HydrophobicContact CG1-CB 4.11Å; I392-W465 HydrophobicContact CG1-CD2 3.85Å; I392-W465 HydrophobicContact CG1-CE3 3.95Å; I392-W465 HydrophobicContact CG1-CG 3.96Å; I392-W465 HydrophobicContact CG2-CB 4.36Å; I392-W465 HydrophobicContact CG2-CD2 4.12Å; I392-W465 HydrophobicContact CG2-CG 3.82Å; P437-W465 HydrophobicContact CB-CD2 3.71Å; P437-W465 HydrophobicContact CB-CE3 3.62Å; P437-W465 HydrophobicContact CB-CG 4.46Å; P437-W465 HydrophobicContact CB-CH2 3.86Å; P437-W465 HydrophobicContact CB-CZ2 3.97Å; P437-W465 HydrophobicContact CB-CZ3 3.68Å; P437-W465 HydrophobicContact CG-CD2 4.19Å; P437-W465 HydrophobicContact CG-CZ2 4.3Å; P437-W465 WeakPolarHBondContact O-CA 3.3Å; L439-W465 HydrophobicContact CB-CE3 4.22Å; L439-W465 HydrophobicContact CB-CZ3 4.44Å; N462-W465 VanDerWaalsContact OD1-CD1 3.28Å; N462-W465 PolarHBondContact OD1-N 2.85Å
466E97.5Very high96.2Very high33 Ų3333.5 Ų33.515%0.15420%0.195CC..EExtended strand (participates in β ladder)trans-111.3112.9171.5-179.5-175.8-163.300108.9T435 P437 R438 L439 I468T435-E466 WeakPolarHBondContact CB-OE2 3.29Å; T435-E466 WeakPolarHBondContact CG2-OE2 3.29Å; P437-E466 PolarHBondContact O-N 3.02Å; R438-E466 CarbonylContact C-O 3.6Å; R438-E466 VanDerWaalsContact CA-O 3.31Å; R438-E466 WeakPolarHBondContact CA-O 3.42Å; R438-E466 HydrophobicContact CG-CB 4.27Å; R438-E466 IonicContact CZ-OE2 2.88Å; R438-E466 IonicContact NE-OE2 2.69Å; R438-E466 PolarHBondContact NE-OE2 3.42Å; R438-E466 IonicContact NH2-OE1 3.85Å; R438-E466 IonicContact NH2-OE2 3.26Å; R438-E466 PolarHBondContact NH2-OE2 2.93Å; L439-E466 PolarHBondContact N-O 3.42Å; E466-I468 HydrophobicContact CG-CG1 4.2Å
467A98.1Very high96.2Very high0 Ų033.7 Ų33.70%020%0.197CC..EExtended strand (participates in β ladder)trans-85.9128.817300000110.3Q45 M388 L439 A455 V458 T459Q45-A467 PolarHBondContact NE2-O 3.24Å; M388-A467 HydrophobicContact SD-CB 4.34Å; L439-A467 CarbonylContact O-C 3.58Å; L439-A467 VanDerWaalsContact O-CA 3.3Å; L439-A467 WeakPolarHBondContact O-CA 3.29Å; A455-A467 HydrophobicContact CB-CB 4.27Å; V458-A467 HydrophobicContact CG1-CB 4.47Å; T459-A467 PolarHBondContact OG1-N 2.91Å
468I98.4Very high96.1Very high12 Ų1233.2 Ų33.26%0.06220%0.198CC..EExtended strand (participates in β ladder)trans-123.3127.3176.7-56.9175.1000107.1Q45 Y47 L85 L439 M440 V441 E466Q45-I468 WeakPolarHBondContact O-CA 3.41Å; Y47-I468 HydrophobicContact CD1-CG2 3.67Å; Y47-I468 HydrophobicContact CE1-CG2 3.96Å; L85-I468 HydrophobicContact CD1-CD1 3.99Å; L439-I468 PolarHBondContact O-N 3Å; M440-I468 CarbonylContact C-O 3.53Å; M440-I468 VanDerWaalsContact CA-O 3.31Å; M440-I468 WeakPolarHBondContact CA-O 3.23Å; M440-I468 HydrophobicContact CG-CB 4.29Å; V441-I468 PolarHBondContact N-O 2.68Å; E466-I468 HydrophobicContact CG-CG1 4.2Å
469I98.8Very high96.1Very high0 Ų035.3 Ų35.30%021%0.213CC..EExtended strand (participates in β ladder)trans-116.6142.9-179.1-172170.9000110.4Q45 V46 Y47 I384 M388 V441 I443 E451 M452 A455Q45-I469 PolarHBondContact O-N 3.01Å; V46-I469 CarbonylContact C-O 3.6Å; V46-I469 WeakPolarHBondContact CA-O 3.5Å; V46-I469 HydrophobicContact CG2-CG2 3.96Å; Y47-I469 WeakPolarHBondContact CD1-O 3.25Å; Y47-I469 PolarHBondContact N-O 3.35Å; I384-I469 HydrophobicContact CG1-CD1 4.29Å; M388-I469 HydrophobicContact CE-CB 3.97Å; M388-I469 HydrophobicContact CE-CD1 3.98Å; M388-I469 HydrophobicContact CE-CG1 4.27Å; V441-I469 HydrophobicContact CB-CG1 4.24Å; V441-I469 HydrophobicContact CG1-CG1 4.17Å; V441-I469 CarbonylContact O-C 3.49Å; V441-I469 WeakPolarHBondContact O-CA 3.49Å; I443-I469 HydrophobicContact CD1-CD1 4.11Å; E451-I469 HydrophobicContact CB-CD1 3.97Å; M452-I469 HydrophobicContact CG-CG2 4.46Å; A455-I469 HydrophobicContact CB-CB 4.17Å; A455-I469 HydrophobicContact CB-CG2 3.7Å
470G98.7Very high96.1Very high0 Ų034.2 Ų34.20%021%0.206CC..EExtended strand (participates in β ladder)trans-157.2175.9172.800000112.9Y47 V441 F442 I443Y47-G470 VanDerWaalsContact CE1-CA 3.47Å; Y47-G470 VanDerWaalsContact CE1-N 3.3Å; Y47-G470 WeakPolarHBondContact O-CA 3.49Å; V441-G470 PolarHBondContact O-N 3.44Å; F442-G470 CarbonylContact C-O 3.51Å; F442-G470 WeakPolarHBondContact CA-O 3.43Å; I443-G470 PolarHBondContact N-O 3.38Å
471S98.8Very high96.3Very high0 Ų027.2 Ų27.20%017%0.173CC..EExtended strand (participates in β ladder)trans-160.8173.2-170.5164.90000110.2Y47 L49 F442 I443 G446 A447 H473Y47-S471 PolarHBondContact O-N 3.01Å; L49-S471 PolarHBondContact N-O 3.09Å; F442-S471 VanDerWaalsContact CE2-C 3.41Å; I443-S471 VanDerWaalsContact O-CA 3.26Å; I443-S471 WeakPolarHBondContact O-CA 3.08Å; I443-S471 WeakPolarHBondContact O-CB 3.45Å; I443-S471 PolarHBondContact O-OG 3.29Å; I443-S471 VanDerWaalsContact O-OG 3.12Å; G446-S471 WeakPolarHBondContact CA-OG 3.33Å; G446-S471 PolarHBondContact N-OG 2.91Å; A447-S471 PolarHBondContact N-OG 2.89Å; A447-S471 VanDerWaalsContact N-OG 3.16Å; S471-H473 VanDerWaalsContact CB-O 3.31Å; S471-H473 WeakPolarHBondContact CB-O 3.46Å; S471-H473 PolarHBondContact O-N 3.17Å; S471-H473 PolarHBondContact OG-N 3.1Å; S471-H473 PolarHBondContact OG-O 3.01Å
472T98.2Very high96.4Very high0 Ų027.8 Ų27.80%016%0.161CC..SBendtrans-59.3-33.717060.50000112.2D50 N51 A54 L74 F442 G445D50-T472 PolarHBondContact N-O 3.06Å; D50-T472 VanDerWaalsContact N-O 3.15Å; N51-T472 PolarHBondContact N-O 2.72Å; N51-T472 WeakPolarHBondContact O-CB 3.19Å; A54-T472 HydrophobicContact CB-CG2 3.65Å; L74-T472 HydrophobicContact CD1-CG2 3.84Å; L74-T472 HydrophobicContact CD2-CG2 3.99Å; F442-T472 HydrophobicContact CZ-CG2 3.86Å; G445-T472 PolarHBondContact N-OG1 2.87Å
473H98.3Very high96.6Very high15 Ų1526 Ų267%0.06915%0.151CC..  trans-160170.7174.262.2-67.9000110.4P52 G446 A447 S471 F475 Q483P52-H473 HydrophobicContact CB-CB 4.29Å; G446-H473 VanDerWaalsContact CA-O 3.28Å; G446-H473 WeakPolarHBondContact CA-O 3.34Å; A447-H473 PolarHBondContact N-O 3.19Å; A447-H473 VanDerWaalsContact N-O 3.12Å; S471-H473 VanDerWaalsContact CB-O 3.31Å; S471-H473 WeakPolarHBondContact CB-O 3.46Å; S471-H473 PolarHBondContact O-N 3.17Å; S471-H473 PolarHBondContact OG-N 3.1Å; S471-H473 PolarHBondContact OG-O 3.01Å; H473-F475 AromaticContact NE2-CD1 3.83Å; H473-Q483 PolarHBondContact NE2-NE2 2.96Å; H473-Q483 PolarHBondContact NE2-OE1 2.64Å
474I97.9Very high97.1Very high33 Ų3322.7 Ų22.717%0.16912%0.116CC..EExtended strand (participates in β ladder)trans-100.9140.5168.4-51.4-54.2000107.5Y42 V46 A447 F449 M452Y42-I474 HydrophobicContact CD1-CG1 3.98Å; Y42-I474 HydrophobicContact CE1-CG1 4.09Å; Y42-I474 HydrophobicContact CG-CG1 4.4Å; V46-I474 HydrophobicContact CG1-CD1 3.95Å; A447-I474 HydrophobicContact CB-CD1 4.17Å; F449-I474 HydrophobicContact CD1-CG2 4.42Å; F449-I474 HydrophobicContact CE1-CG2 3.93Å; F449-I474 HydrophobicContact CE2-CG2 4.03Å; F449-I474 HydrophobicContact CZ-CG2 3.71Å; M452-I474 HydrophobicContact SD-CD1 3.91Å; M452-I474 HydrophobicContact SD-CG1 4.32Å; M452-I474 HydrophobicContact SD-CG2 3.68Å
475F94.9Very high97.3Very high5 Ų519.5 Ų19.52%0.02210%0.102CC..EExtended strand (participates in β ladder)trans-132.7161.9178.465.7-118.5000112.7P144 G446 A447 H473 C479 L480P144-F475 HydrophobicContact CB-CE2 3.59Å; P144-F475 HydrophobicContact CB-CZ 3.62Å; P144-F475 HydrophobicContact CG-CE2 4.29Å; P144-F475 HydrophobicContact CG-CZ 3.88Å; G446-F475 VanDerWaalsContact CA-CD1 3.46Å; G446-F475 VanDerWaalsContact CA-CE1 3.41Å; G446-F475 WeakPolarHBondContact O-CE1 3.28Å; A447-F475 PolarHBondContact O-N 2.94Å; H473-F475 AromaticContact NE2-CD1 3.83Å; F475-C479 HydrophobicContact CB-CB 3.9Å; F475-L480 HydrophobicContact CD2-CB 4.07Å; F475-L480 HydrophobicContact CE2-CB 4.19Å; F475-L480 HydrophobicContact CE2-CD2 4.36Å; F475-L480 HydrophobicContact CG-CB 4.42Å; F475-L480 HydrophobicContact CZ-CD2 4.39Å
476T97.8Very high97.1Very high20 Ų2020.2 Ų20.212%0.12311%0.11CC..  trans-97.4163.416367.90000109.9Y156 F449 T478 C479 L480Y156-T476 VanDerWaalsContact O-CG2 3.31Å; Y156-T476 WeakPolarHBondContact O-CG2 3.27Å; F449-T476 HydrophobicContact CE2-CG2 4.19Å; T476-T478 PolarHBondContact O-N 3.44Å; T476-C479 PolarHBondContact O-N 2.8Å; T476-C479 VanDerWaalsContact O-N 3.09Å; T476-C479 PolarHBondContact OG1-N 2.78Å; T476-C479 PolarHBondContact OG1-SG 2.86Å; T476-L480 PolarHBondContact O-N 3.49Å; T476-L480 VanDerWaalsContact O-N 3.07Å
477P98.2Very high96.6Very high15 Ų1518.6 Ų18.610%0.09710%0.102CC..Hα-helixtrans-51.7-42.4174.2-28.437000112.4P144 D157 L480 L481P144-P477 WeakPolarHBondContact O-CA 3.25Å; P144-P477 WeakPolarHBondContact O-CG 3.4Å; D157-P477 HydrophobicContact CB-CG 4.47Å; D157-P477 WeakPolarHBondContact OD1-CG 3.47Å; P477-L480 PolarHBondContact O-N 3.14Å; P477-L481 WeakPolarHBondContact O-CG 3.18Å; P477-L481 PolarHBondContact O-N 2.81Å; P477-L481 VanDerWaalsContact O-N 3.08Å
478T97Very high95.7Very high49 Ų4920.9 Ų20.930%0.30112%0.115SC..Hα-helixtrans-59.4-48.3175.7-56.80000112.2Y304 T476 L480 L481 E482Y304-T478 HydrophobicContact CD2-CG2 4.01Å; Y304-T478 HydrophobicContact CE2-CG2 3.87Å; T476-T478 PolarHBondContact O-N 3.44Å; T478-L480 VanDerWaalsContact C-N 3.31Å; T478-L480 PolarHBondContact O-N 3.25Å; T478-L481 PolarHBondContact O-N 3.44Å; T478-L481 VanDerWaalsContact O-N 3.16Å; T478-E482 WeakPolarHBondContact O-CG 3.25Å; T478-E482 PolarHBondContact O-N 3.26Å
479C95.3Very high94.6Very high49 Ų4924.9 Ų24.933%0.33113%0.132SC..Hα-helixtrans-60.4-38.8178.1-67.70000112.5F475 T476 E482 Q483F475-C479 HydrophobicContact CB-CB 3.9Å; T476-C479 PolarHBondContact O-N 2.8Å; T476-C479 VanDerWaalsContact O-N 3.09Å; T476-C479 PolarHBondContact OG1-N 2.78Å; T476-C479 PolarHBondContact OG1-SG 2.86Å; C479-E482 PolarHBondContact O-N 3.31Å; C479-Q483 WeakPolarHBondContact O-CG 3.29Å; C479-Q483 PolarHBondContact O-N 2.92Å
480L97.5Very high93.1Very high2 Ų228 Ų281%0.0115%0.152CC..Hα-helixtrans-62.6-46.4175.1172.764.5000111.4F55 P144 V145 F475 T476 P477 T478 E482 Q483 L484F55-L480 HydrophobicContact CE2-CD1 3.92Å; F55-L480 HydrophobicContact CZ-CD1 3.86Å; P144-L480 HydrophobicContact CB-CD2 3.44Å; P144-L480 VanDerWaalsContact CB-CD2 3.44Å; P144-L480 HydrophobicContact CG-CD2 4.47Å; V145-L480 HydrophobicContact CG1-CD2 4.05Å; F475-L480 HydrophobicContact CD2-CB 4.07Å; F475-L480 HydrophobicContact CE2-CB 4.19Å; F475-L480 HydrophobicContact CE2-CD2 4.36Å; F475-L480 HydrophobicContact CG-CB 4.42Å; F475-L480 HydrophobicContact CZ-CD2 4.39Å; T476-L480 PolarHBondContact O-N 3.49Å; T476-L480 VanDerWaalsContact O-N 3.07Å; P477-L480 PolarHBondContact O-N 3.14Å; T478-L480 VanDerWaalsContact C-N 3.31Å; T478-L480 PolarHBondContact O-N 3.25Å; L480-E482 VanDerWaalsContact C-N 3.29Å; L480-E482 PolarHBondContact O-N 2.83Å; L480-Q483 PolarHBondContact O-N 2.77Å; L480-L484 HydrophobicContact CD1-CD1 4.1Å; L480-L484 HydrophobicContact CD1-CG 4.28Å; L480-L484 HydrophobicContact CG-CD1 3.99Å; L480-L484 WeakPolarHBondContact O-CG 3.34Å; L480-L484 PolarHBondContact O-N 3.45Å
481L98.1Very high91.6Very high1 Ų132 Ų321%0.00517%0.173CC..Hα-helixtrans-62.9-37.5179.1-64.3175.4000111.5Y304 I307 R308 L311 I341 P477 T478 L484 K485Y304-L481 HydrophobicContact CD2-CB 4.13Å; Y304-L481 HydrophobicContact CD2-CD1 3.73Å; Y304-L481 HydrophobicContact CE2-CB 4.06Å; Y304-L481 HydrophobicContact CE2-CD1 4.49Å; Y304-L481 HydrophobicContact CG-CD1 3.79Å; I307-L481 HydrophobicContact CG2-CD2 3.86Å; R308-L481 HydrophobicContact CG-CD1 4.11Å; L311-L481 HydrophobicContact CD1-CD2 3.98Å; I341-L481 HydrophobicContact CD1-CB 4.42Å; I341-L481 HydrophobicContact CG2-CB 4.25Å; I341-L481 HydrophobicContact CG2-CD2 3.53Å; I341-L481 HydrophobicContact CG2-CG 4.47Å; P477-L481 WeakPolarHBondContact O-CG 3.18Å; P477-L481 PolarHBondContact O-N 2.81Å; P477-L481 VanDerWaalsContact O-N 3.08Å; T478-L481 PolarHBondContact O-N 3.44Å; T478-L481 VanDerWaalsContact O-N 3.16Å; L481-L484 PolarHBondContact O-N 3.18Å; L481-K485 WeakPolarHBondContact O-CB 3.48Å; L481-K485 PolarHBondContact O-N 3.14Å
482E96.1Very high89.7Confident100 Ų10040.6 Ų40.647%0.46721%0.213SC..Hα-helixtrans-65.7-43.3174.7-72.5172.8171.400112.8Y304 T478 C479 L480 L484 K485 A486Y304-E482 HydrophobicContact CE2-CG 4.13Å; T478-E482 WeakPolarHBondContact O-CG 3.25Å; T478-E482 PolarHBondContact O-N 3.26Å; C479-E482 PolarHBondContact O-N 3.31Å; L480-E482 VanDerWaalsContact C-N 3.29Å; L480-E482 PolarHBondContact O-N 2.83Å; E482-L484 VanDerWaalsContact C-N 3.32Å; E482-L484 PolarHBondContact O-N 3.49Å; E482-K485 WeakPolarHBondContact O-CB 3.31Å; E482-K485 PolarHBondContact O-N 3.36Å; E482-A486 PolarHBondContact O-N 3.15Å
483Q95.4Very high87.5Confident25 Ų2546.4 Ų46.412%0.11724%0.24CC..Hα-helixtrans-62.6-39.9174.3-73.6-178.4-0.100111.7F55 H56 H473 C479 L480 K485 A486 M487F55-Q483 HydrophobicContact CD1-CB 3.6Å; F55-Q483 HydrophobicContact CD1-CG 4.29Å; F55-Q483 HydrophobicContact CE1-CB 3.61Å; F55-Q483 HydrophobicContact CG-CB 4.34Å; F55-Q483 HydrophobicContact CZ-CB 4.36Å; H56-Q483 PolarHBondContact NE2-O 2.97Å; H473-Q483 PolarHBondContact NE2-NE2 2.96Å; H473-Q483 PolarHBondContact NE2-OE1 2.64Å; C479-Q483 WeakPolarHBondContact O-CG 3.29Å; C479-Q483 PolarHBondContact O-N 2.92Å; L480-Q483 PolarHBondContact O-N 2.77Å; Q483-K485 VanDerWaalsContact C-N 3.34Å; Q483-A486 PolarHBondContact O-N 2.82Å; Q483-M487 PolarHBondContact O-N 3.49Å
484L96.5Very high85.2Confident0 Ų049.4 Ų49.40%026%0.26CS..Hα-helixtrans-65.1-37.9173.7-71.4166.2000112F55 I341 N344 M345 L348 L480 L481 E482 A486 M487F55-L484 HydrophobicContact CE1-CD2 4.31Å; F55-L484 HydrophobicContact CE1-CG 4.47Å; F55-L484 HydrophobicContact CZ-CD2 3.98Å; F55-L484 HydrophobicContact CZ-CG 4.21Å; I341-L484 HydrophobicContact CB-CB 4.5Å; I341-L484 HydrophobicContact CG2-CB 3.85Å; I341-L484 HydrophobicContact CG2-CD1 4.09Å; N344-L484 HydrophobicContact CB-CD2 4.4Å; N344-L484 PolarHBondContact ND2-O 3.42Å; M345-L484 HydrophobicContact CE-CD1 3.42Å; M345-L484 VanDerWaalsContact CE-CD1 3.42Å; M345-L484 HydrophobicContact SD-CD1 4.26Å; L348-L484 HydrophobicContact CD1-CD2 3.91Å; L480-L484 HydrophobicContact CD1-CD1 4.1Å; L480-L484 HydrophobicContact CD1-CG 4.28Å; L480-L484 HydrophobicContact CG-CD1 3.99Å; L480-L484 WeakPolarHBondContact O-CG 3.34Å; L480-L484 PolarHBondContact O-N 3.45Å; L481-L484 PolarHBondContact O-N 3.18Å; E482-L484 VanDerWaalsContact C-N 3.32Å; E482-L484 PolarHBondContact O-N 3.49Å; L484-A486 VanDerWaalsContact C-N 3.26Å; L484-A486 PolarHBondContact O-N 2.87Å; L484-M487 HydrophobicContact CD2-CE 3.82Å; L484-M487 VanDerWaalsContact O-CB 3.3Å; L484-M487 WeakPolarHBondContact O-CB 3.35Å; L484-M487 PolarHBondContact O-N 3.47Å
485K95.3Very high82.3Confident41 Ų4153.9 Ų53.918%0.17829%0.289CS..Hα-helixtrans-62.1-34.7175.5-166.5173.8179.4172.50111.8E337 D338 I341 L481 E482 Q483E337-K485 IonicContact OE1-NZ 3.06Å; E337-K485 PolarHBondContact OE1-NZ 3.16Å; D338-K485 WeakPolarHBondContact OD1-CD 3.41Å; D338-K485 WeakPolarHBondContact OD1-CE 3.33Å; D338-K485 IonicContact OD1-NZ 3.74Å; D338-K485 PolarHBondContact OD1-NZ 3.36Å; I341-K485 HydrophobicContact CD1-CB 3.94Å; I341-K485 HydrophobicContact CD1-CD 4.27Å; I341-K485 HydrophobicContact CD1-CG 4.26Å; I341-K485 HydrophobicContact CG1-CB 3.69Å; I341-K485 HydrophobicContact CG1-CG 4.15Å; L481-K485 WeakPolarHBondContact O-CB 3.48Å; L481-K485 PolarHBondContact O-N 3.14Å; E482-K485 WeakPolarHBondContact O-CB 3.31Å; E482-K485 PolarHBondContact O-N 3.36Å; Q483-K485 VanDerWaalsContact C-N 3.34Å
486A91.8Very high79.2Confident24 Ų2461.4 Ų61.420%0.19834%0.342CS..THydrogen-bonded Turntrans-83.7-5-179.400000114.4E482 Q483 L484 N488 K489E482-A486 PolarHBondContact O-N 3.15Å; Q483-A486 PolarHBondContact O-N 2.82Å; L484-A486 VanDerWaalsContact C-N 3.26Å; L484-A486 PolarHBondContact O-N 2.87Å; A486-N488 PolarHBondContact O-N 3.25Å; A486-K489 PolarHBondContact O-N 3.06Å
487M86.6Confident78.2Confident0 Ų063.5 Ų63.50%035%0.353CS..THydrogen-bonded Turntrans-65.7-34.3-168.1-169.8167.3-71.500115.4F55 S60 N344 H347 L348 Q483 L484F55-M487 HydrophobicContact CD1-CE 4.12Å; F55-M487 HydrophobicContact CE1-CE 3.32Å; F55-M487 HydrophobicContact CZ-CE 3.89Å; S60-M487 WeakPolarHBondContact CB-O 3.25Å; S60-M487 PolarHBondContact OG-O 2.92Å; N344-M487 HydrophobicContact CB-CB 4.25Å; N344-M487 HydrophobicContact CB-SD 4.11Å; H347-M487 HydrophobicContact CB-SD 3.42Å; H347-M487 WeakPolarHBondContact CB-SD 3.16Å; H347-M487 PolarHBondContact CD2-SD 3.41Å; L348-M487 HydrophobicContact CD1-CE 3.87Å; Q483-M487 PolarHBondContact O-N 3.49Å; L484-M487 HydrophobicContact CD2-CE 3.82Å; L484-M487 VanDerWaalsContact O-CB 3.3Å; L484-M487 WeakPolarHBondContact O-CB 3.35Å; L484-M487 PolarHBondContact O-N 3.47Å
488N79.9Confident77.2Confident48 Ų4866.1 Ų66.126%0.25737%0.367SS..THydrogen-bonded Turntrans-95-1.7-178.2-63.1-17.8000113.4E340 N344 A486E340-N488 PolarHBondContact OE2-ND2 2.91Å; E340-N488 VanDerWaalsContact OE2-ND2 3.12Å; N344-N488 VanDerWaalsContact CG-ND2 3.35Å; N344-N488 PolarHBondContact ND2-ND2 3.07Å; N344-N488 PolarHBondContact OD1-ND2 3.37Å; N344-N488 PolarHBondContact OD1-OD1 3.24Å; A486-N488 PolarHBondContact O-N 3.25Å
489K76.1Confident76.1Confident96 Ų9667 Ų6742%0.41737%0.37SS..SBendtrans-79131.1-177-64.4-168.8177.6-172.40110.1A486 V494A486-K489 PolarHBondContact O-N 3.06Å; K489-V494 HydrophobicContact CB-CG2 4.14Å
490P67.6Low74.9Confident66 Ų6668.1 Ų68.143%0.42937%0.373SS..  trans-64.4150172.826.1-30.8000110.4E492 E493P490-E492 PolarHBondContact O-N 3.25Å; P490-E493 HydrophobicContact CG-CG 4.35Å; P490-E493 PolarHBondContact O-N 3.02Å; P490-E493 VanDerWaalsContact O-N 3.09Å
491D65.9Low73.5Confident84 Ų8472.2 Ų72.245%0.44940%0.395SS..G310 helixtrans-56.5-24.6-174.7-86.1-38.5000114.2K63 E493K63-D491 WeakPolarHBondContact CE-OD1 3.43Å; K63-D491 IonicContact NZ-OD1 3.44Å; K63-D491 PolarHBondContact NZ-OD1 3.09Å; D491-E493 VanDerWaalsContact C-N 3.29Å; D491-E493 PolarHBondContact O-N 3.16Å
492E59.1Low71.9Confident180 Ų18076.9 Ų76.984%0.84142%0.421SS*.G310 helixtrans-70.3-19.3-179.7-63.1-176.3177.200113.9P490P490-E492 PolarHBondContact O-N 3.25Å
493E51.5Low70.2Confident121 Ų12175.3 Ų75.357%0.56542%0.418SS*.G310 helixtrans-99.5-9.6-177.1-70.8-173.216600114.3P490 D491 S496P490-E493 HydrophobicContact CG-CG 4.35Å; P490-E493 PolarHBondContact O-N 3.02Å; P490-E493 VanDerWaalsContact O-N 3.09Å; D491-E493 VanDerWaalsContact C-N 3.29Å; D491-E493 PolarHBondContact O-N 3.16Å; E493-S496 PolarHBondContact O-OG 3.47Å
494V51.6Low68.2Low78 Ų7879.2 Ų79.247%0.47344%0.441SS..THydrogen-bonded Turntrans-88.7-13.9-173.8-174.80000112.2K489K489-V494 HydrophobicContact CB-CG2 4.14Å
495T35.4Very low65.9Low128 Ų12885.8 Ų85.879%0.78548%0.478SS*.THydrogen-bonded Turntrans-97.18.6-177.647.60000115.4
496S29.7Very low63.2Low163 Ų16389.8 Ų89.8100%1.1451%0.505SS*.  trans-104.50-178.362.50000113.8E493E493-S496 PolarHBondContact O-OG 3.47Å

Retrieved 496 of 496 residues in 247 ms (Link to these results)