A0A096LTC9_POEFO Loading...

Presenilin

Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.

AlphaFold DB , UniProt , Accession A0A096LTC9, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 476 aa.

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(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	37.7	Very low	38.9	Very low	242 Å²	242	153 Å²	153	100%	1.192	85%	0.846	S	S	*	*				0	80.6	0	-70.7	171.6	173.8	0	0	105.4
2	A	34.9	Very low	39	Very low	90 Å²	90	154.9 Å²	154.9	74%	0.744	85%	0.848	S	S	*	*				73.9	120	78.2	0	0	0	0	0	112.6
3	N	36.1	Very low	38.6	Very low	148 Å²	148	157.3 Å²	157.3	79%	0.791	85%	0.845	S	S	*	*			trans	83	133.1	155.4	-68.4	15.9	0	0	0	116.9
4	N	39.2	Very low	38.1	Very low	123 Å²	123	157.9 Å²	157.9	66%	0.658	85%	0.848	S	S	*	*			cis	-150.7	145.8	16.2	-97.1	-16.9	0	0	0	111.7
5	A	42.7	Very low	37.6	Very low	97 Å²	97	160.9 Å²	160.9	80%	0.802	86%	0.855	S	S	*	*			trans	-93	116.9	160.9	0	0	0	0	0	107.3
6	E	42.6	Very low	37.1	Very low	166 Å²	166	162.5 Å²	162.5	78%	0.776	86%	0.855	S	S	*	*			trans	-167.9	26.5	170.5	-115.7	169.1	179.2	0	0	114.9
7	D	42.2	Very low	36.6	Very low	168 Å²	168	164.4 Å²	164.4	90%	0.898	86%	0.858	S	S	*	*			trans	-109.5	25.1	-177.8	-74.9	-38.2	0	0	0	114.7
8	V	44.4	Very low	36.2	Very low	138 Å²	138	160.4 Å²	160.4	84%	0.836	85%	0.854	S	S	*	*	S	Bend	trans	-130.2	50.7	176.3	-166.5	0	0	0	0	110.9
9	E	39.2	Very low	35.7	Very low	182 Å²	182	160.3 Å²	160.3	85%	0.85	85%	0.853	S	S	*	*	S	Bend	trans	-160.3	38.9	166.2	-144.9	159.1	127.2	0	0	115.2
10	N	35	Very low	35.4	Very low	157 Å²	157	157.3 Å²	157.3	84%	0.84	85%	0.846	S	S	*	*			trans	-141.7	21.2	179.4	-96.9	-23.2	0	0	0	116.7
11	N	33.8	Very low	35.3	Very low	172 Å²	172	155.2 Å²	155.2	92%	0.92	84%	0.844	S	S	*	*	S	Bend	trans	-102.8	27.6	171.5	-145.5	-3	0	0	0	113.5
12	M	40.2	Very low	35.5	Very low	176 Å²	176	149 Å²	149	87%	0.867	82%	0.821	S	S	*	*	S	Bend	trans	-140.2	58.2	-178.5	-157.6	166.3	-171.3	0	0	110.3
13	K	33.4	Very low	35.3	Very low	186 Å²	186	153.6 Å²	153.6	81%	0.809	83%	0.827	S	S	*	*	S	Bend	trans	174.5	94.7	163.8	-94.1	145.4	-171.4	-179.3	0	107.6
14	D	32.4	Very low	34.9	Very low	165 Å²	165	150.9 Å²	150.9	88%	0.882	83%	0.825	S	S	*	*			trans	167.3	70.9	146.4	-84.4	-20.6	0	0	0	110
15	Q	30.9	Very low	34.5	Very low	204 Å²	204	149 Å²	149	95%	0.953	83%	0.827	S	S	*	*			trans	-154.6	73.7	151.1	-116.3	174.7	27.2	0	0	108.9
16	Q	28.7	Very low	33.8	Very low	186 Å²	186	153.4 Å²	153.4	87%	0.869	83%	0.831	S	S	*	*			trans	-143.4	97.4	166.9	-156.5	168.2	23.5	0	0	109
17	Q	28.7	Very low	33.4	Very low	194 Å²	194	154.5 Å²	154.5	91%	0.907	84%	0.836	S	S	*	*			trans	165.3	113.9	138.6	-95.2	171.7	-5.2	0	0	111
18	A	28.9	Very low	32.9	Very low	94 Å²	94	152 Å²	152	78%	0.777	83%	0.829	S	S	*	*				178.6	137.3	109.4	0	0	0	0	0	112.9
19	N	28.3	Very low	32.2	Very low	157 Å²	157	154.3 Å²	154.3	84%	0.84	83%	0.831	S	S	*	*			trans	80.3	122	165.3	-74.1	4.7	0	0	0	120.2
20	S	29.5	Very low	31.7	Very low	101 Å²	101	155 Å²	155	71%	0.706	83%	0.834	S	S	*	*			cis	175.5	123	-19.6	34	0	0	0	0	106.7
21	S	32	Very low	31.5	Very low	114 Å²	114	151.8 Å²	151.8	80%	0.797	83%	0.829	S	S	*	*			trans	-71.7	176.7	160.1	-42.2	0	0	0	0	110.4
22	P	43.5	Very low	32.1	Very low	111 Å²	111	149.4 Å²	149.4	72%	0.721	82%	0.823	S	S	*	*				-137.7	151	62.2	15.2	11.9	0	0	0	114.3
23	E	29.4	Very low	31.7	Very low	187 Å²	187	145.1 Å²	145.1	87%	0.874	82%	0.815	S	S	*	*				65.6	137.9	93.3	-119.9	176.3	122.4	0	0	113.2
24	A	28.7	Very low	31.5	Very low	90 Å²	90	142.5 Å²	142.5	74%	0.744	82%	0.815	S	S	*	*			cis	-166.9	177	27	0	0	0	0	0	111.9
25	A	30.8	Very low	31.4	Very low	84 Å²	84	146.3 Å²	146.3	69%	0.694	82%	0.817	S	S	*	*			trans	-43.7	152.5	179.4	0	0	0	0	0	120.2
26	Q	28.1	Very low	31.4	Very low	189 Å²	189	141 Å²	141	88%	0.883	81%	0.808	S	S	*	*				168.6	134.6	116.8	-94.5	160.8	-18.1	0	0	113.1
27	Q	32.4	Very low	31.4	Very low	189 Å²	189	143.6 Å²	143.6	88%	0.883	81%	0.81	S	S	*	*			trans	-64.9	143.1	153.8	-91.3	176.2	-17.6	0	0	109
28	P	33.6	Very low	31.6	Very low	116 Å²	116	139.8 Å²	139.8	75%	0.753	81%	0.805	S	S	*	*				-149.3	153.4	87.1	34.1	-13.8	0	0	0	116.4
29	Q	29.3	Very low	31.6	Very low	187 Å²	187	147.3 Å²	147.3	87%	0.874	81%	0.813	S	S	*	*			trans	25.2	114.9	132.2	-149.7	168.1	29.2	0	0	119.5
30	E	28.5	Very low	31.7	Very low	195 Å²	195	143.1 Å²	143.1	91%	0.911	81%	0.807	S	S	*	*			trans	-169	109	140.8	-109.4	175.4	-179.7	0	0	112.7
31	A	30.6	Very low	31.5	Very low	90 Å²	90	141.5 Å²	141.5	74%	0.744	81%	0.807	S	S	*	*			trans	-97.4	-179.6	136.7	0	0	0	0	0	106.3
32	P	46.6	Very low	31.4	Very low	123 Å²	123	142.7 Å²	142.7	80%	0.799	82%	0.815	S	S	*	*			cis	-139.5	179.4	7.5	34.7	-10.5	0	0	0	114
33	A	31.2	Very low	30.8	Very low	85 Å²	85	140.6 Å²	140.6	70%	0.702	81%	0.813	S	S	*	*				150.9	149.3	106.9	0	0	0	0	0	106.6
34	T	30	Very low	30.8	Very low	132 Å²	132	138.9 Å²	138.9	81%	0.81	81%	0.81	S	S	*	*			cis	-170.2	120.4	37	-21.2	0	0	0	0	105.9
35	R	30.3	Very low	31	Very low	244 Å²	244	143.2 Å²	143.2	92%	0.921	82%	0.815	S	S	*	*				54.4	110.5	83.1	-153.5	-177.4	-165.5	-178.9	5	117
36	A	30.3	Very low	30.9	Very low	92 Å²	92	142.6 Å²	142.6	76%	0.76	82%	0.817	S	S	*	*			trans	-174.3	138.8	135.1	0	0	0	0	0	108.5
37	R	28.8	Very low	30.9	Very low	242 Å²	242	137.8 Å²	137.8	91%	0.913	82%	0.818	S	S	*	*			cis	-165.6	136.4	-2.8	-126.4	176.9	179.8	174.6	-0	106.4
38	S	32.2	Very low	30.8	Very low	114 Å²	114	132.7 Å²	132.7	80%	0.797	82%	0.816	S	S	*	*			trans	-83.1	148.6	158.6	174.8	0	0	0	0	109.5
39	R	29.9	Very low	30.9	Very low	251 Å²	251	135.4 Å²	135.4	95%	0.947	82%	0.824	S	S	*	*			trans	-136.2	107.3	153.1	-120.7	-179.9	172.1	180	-4	103.2
40	G	29	Very low	31	Very low	70 Å²	70	129.3 Å²	129.3	72%	0.722	81%	0.811	S	S	*	*				75.5	115.7	81.3	0	0	0	0	0	107.6
41	G	27.1	Very low	31.2	Very low	67 Å²	67	125.7 Å²	125.7	69%	0.691	81%	0.808	S	S	*	*			cis	123.1	140.6	35.7	0	0	0	0	0	106.9
42	S	29.7	Very low	31.1	Very low	139 Å²	139	125 Å²	125	97%	0.972	81%	0.809	S	S	*	*			trans	74.9	143.2	171	-35.8	0	0	0	0	114.4
43	G	29.4	Very low	31.1	Very low	66 Å²	66	125 Å²	125	68%	0.68	81%	0.809	S	S	*	*			cis	155.3	123.3	16.4	0	0	0	0	0	103.5
44	D	31.3	Very low	31.6	Very low	151 Å²	151	129.7 Å²	129.7	81%	0.807	82%	0.816	S	S	*	*				78.5	146.8	119.7	-157.6	27.5	0	0	0	116.1
45	E	31.9	Very low	31.8	Very low	182 Å²	182	132.8 Å²	132.8	85%	0.85	82%	0.822	S	S	*	*			trans	68.7	139.3	173.1	-56.1	-179.5	98.5	0	0	115.8
46	G	29.1	Very low	32.1	Very low	71 Å²	71	129.2 Å²	129.2	73%	0.732	82%	0.821	S	S	*	*			cis	178.3	166.3	12.9	0	0	0	0	0	106.7
47	G	28.2	Very low	32.6	Very low	88 Å²	88	128 Å²	128	91%	0.907	82%	0.818	S	S	*	*			trans	-64.3	178.2	-166.4	0	0	0	0	0	117.2
48	G	29.3	Very low	32.9	Very low	81 Å²	81	125.2 Å²	125.2	84%	0.835	82%	0.815	S	S	*	*			trans	165.2	94.8	173	0	0	0	0	0	113.3
49	D	35.8	Very low	33.3	Very low	174 Å²	174	125 Å²	125	93%	0.93	81%	0.811	S	S	*	*			trans	-54.1	153.8	165.5	-161.4	7.5	0	0	0	112.9
50	G	31.2	Very low	33.9	Very low	58 Å²	58	119.2 Å²	119.2	60%	0.598	81%	0.806	S	S	*	*			trans	150.6	92.2	165.9	0	0	0	0	0	118.7
51	S	32.6	Very low	34.4	Very low	120 Å²	120	120.1 Å²	120.1	84%	0.839	81%	0.807	S	S	*	*				44.1	130.6	129.1	58.6	0	0	0	0	122.3
52	G	30.3	Very low	35.4	Very low	76 Å²	76	121.7 Å²	121.7	78%	0.784	81%	0.813	S	S	*	*			trans	-66.6	-145.4	-176.1	0	0	0	0	0	118.3
53	P	46.4	Very low	36	Very low	123 Å²	123	123.4 Å²	123.4	80%	0.799	81%	0.805	S	S	*	*			cis	-129.2	-169.1	0.3	39.4	-18.8	0	0	0	114.9
54	E	41.1	Very low	36.7	Very low	182 Å²	182	124.6 Å²	124.6	85%	0.85	80%	0.801	S	S	*	*			trans	-33.7	147.4	177.5	-58.8	160.8	87	0	0	120.3
55	Q	35	Very low	37.5	Very low	197 Å²	197	121.4 Å²	121.4	92%	0.921	80%	0.795	S	S	*	*			trans	-163.4	115.7	134.2	-121.7	169.5	46.5	0	0	116.4
56	N	36.3	Very low	38.1	Very low	170 Å²	170	122.1 Å²	122.1	91%	0.909	79%	0.79	S	S	*	*			trans	3.9	137.4	147.1	-96.6	-12.8	0	0	0	122.7
57	G	39.3	Very low	39.2	Very low	67 Å²	67	122.5 Å²	122.5	69%	0.691	78%	0.778	S	S	*	*				116	83.3	120.2	0	0	0	0	0	118.9
58	Q	35.7	Very low	40.3	Very low	182 Å²	182	122 Å²	122	85%	0.85	76%	0.758	S	S	*	*			trans	-144	128.3	159.4	-147.1	90.3	33.9	0	0	110
59	P	40	Very low	41.4	Very low	111 Å²	111	124.2 Å²	124.2	72%	0.721	75%	0.746	S	S	*	*	P	Polyproline II helix	trans	-69.7	144	173.7	28.4	-32.4	0	0	0	110.1	A61	P59-A61 PolarHBondContact O-N 3.31Å
60	P	43.6	Very low	42.1	Very low	129 Å²	129	119.9 Å²	119.9	84%	0.838	72%	0.723	S	S	*	*	P	Polyproline II helix	trans	-67.7	129.8	175.6	26.4	-29.9	0	0	0	109.7
61	A	39.9	Very low	43.3	Very low	89 Å²	89	122.3 Å²	122.3	74%	0.736	72%	0.719	S	S	*	*	P	Polyproline II helix	trans	-60	140.5	172.5	0	0	0	0	0	110.2	P59 H63	P59-A61 PolarHBondContact O-N 3.31Å; A61-H63 PolarHBondContact O-N 3.06Å
62	A	47.2	Very low	44.5	Very low	99 Å²	99	122.2 Å²	122.2	82%	0.818	71%	0.705	S	S	*	*	P	Polyproline II helix	trans	-54.2	122.6	175.6	0	0	0	0	0	110.7
63	H	43.3	Very low	45.7	Very low	175 Å²	175	124.7 Å²	124.7	81%	0.81	70%	0.696	S	S	*	*	P	Polyproline II helix	trans	-60.2	133.5	167.9	-81.3	-63.3	0	0	0	109.3	A61	A61-H63 PolarHBondContact O-N 3.06Å
64	P	42.4	Very low	46.2	Very low	92 Å²	92	123.5 Å²	123.5	60%	0.597	68%	0.68	S	S	*	*	P	Polyproline II helix	trans	-69.7	145.2	177.3	28.8	-31.7	0	0	0	109.9	R66	P64-R66 PolarHBondContact O-N 3.32Å
65	A	49.8	Very low	46.9	Very low	83 Å²	83	119.2 Å²	119.2	69%	0.686	66%	0.663	S	S	*	*	T	Hydrogen-bonded Turn	trans	-59.8	13.8	177.4	0	0	0	0	0	115.6
66	R	44.5	Very low	48.2	Very low	198 Å²	198	116.5 Å²	116.5	75%	0.747	65%	0.65	S	S	*	*	H	α-helix	trans	-88.9	-13.1	-174.4	-160.5	174.9	173.6	175.4	-1.4	113.6	P64	P64-R66 PolarHBondContact O-N 3.32Å
67	V	50.4	Low	49.3	Very low	78 Å²	78	114.9 Å²	114.9	47%	0.473	64%	0.637	S	S	.	*	H	α-helix	trans	-82.4	-33.4	177.4	-173.8	0	0	0	0	110.8	N70 E71	V67-N70 PolarHBondContact O-N 3.22Å; V67-E71 HydrophobicContact CG1-CG 4.47Å; V67-E71 VanDerWaalsContact O-CG 3.31Å; V67-E71 WeakPolarHBondContact O-CG 3.15Å; V67-E71 PolarHBondContact O-N 2.91Å
68	V	52.8	Low	50.1	Low	79 Å²	79	115.5 Å²	115.5	48%	0.479	62%	0.623	S	S	.	*	H	α-helix	trans	-72.6	-39.8	-179.5	-173.1	0	0	0	0	111.9	N70 E71 E72	V68-N70 VanDerWaalsContact C-N 3.3Å; V68-N70 PolarHBondContact O-N 3.39Å; V68-E71 PolarHBondContact O-N 3.14Å; V68-E72 HydrophobicContact CG1-CG 4.47Å; V68-E72 WeakPolarHBondContact O-CB 3.29Å; V68-E72 WeakPolarHBondContact O-CG 3.4Å; V68-E72 PolarHBondContact O-N 3.28Å
69	E	51.3	Low	51.5	Low	127 Å²	127	111.5 Å²	111.5	59%	0.593	61%	0.611	S	S	*	*	H	α-helix	trans	-65.3	-33.5	175.2	-70.9	179.8	157	0	0	112.2	E73	E69-E73 WeakPolarHBondContact O-CB 3.5Å; E69-E73 VanDerWaalsContact O-CG 3.3Å; E69-E73 WeakPolarHBondContact O-CG 3.3Å; E69-E73 PolarHBondContact O-N 2.81Å
70	N	51.7	Low	52.8	Low	83 Å²	83	112.8 Å²	112.8	44%	0.444	61%	0.611	S	S	.	*	H	α-helix	trans	-76.4	-34.8	179.2	-135.6	75.7	0	0	0	111.7	V67 V68 E74	V67-N70 PolarHBondContact O-N 3.22Å; V68-N70 VanDerWaalsContact C-N 3.3Å; V68-N70 PolarHBondContact O-N 3.39Å; N70-E74 PolarHBondContact ND2-OE1 3.21Å; N70-E74 VanDerWaalsContact O-CB 3.27Å; N70-E74 WeakPolarHBondContact O-CB 3.32Å; N70-E74 WeakPolarHBondContact O-CG 3.3Å; N70-E74 PolarHBondContact O-N 3.5Å
71	E	55.1	Low	53.9	Low	108 Å²	108	113.9 Å²	113.9	51%	0.505	60%	0.603	S	S	.	*	H	α-helix	trans	-68.6	-41.4	173	-73.2	172.6	176.6	0	0	111.4	V67 V68 E74 D75	V67-E71 HydrophobicContact CG1-CG 4.47Å; V67-E71 VanDerWaalsContact O-CG 3.31Å; V67-E71 WeakPolarHBondContact O-CG 3.15Å; V67-E71 PolarHBondContact O-N 2.91Å; V68-E71 PolarHBondContact O-N 3.14Å; E71-E74 PolarHBondContact O-N 2.95Å; E71-D75 WeakPolarHBondContact O-CB 3.43Å; E71-D75 VanDerWaalsContact O-CG 3.25Å; E71-D75 PolarHBondContact O-N 3.09Å
72	E	57.4	Low	55.1	Low	118 Å²	118	113.7 Å²	113.7	55%	0.551	58%	0.584	S	S	*	*	H	α-helix	trans	-66.8	-40.6	175.2	-72.1	177.7	-174	0	0	112.5	V68 D75 E76	V68-E72 HydrophobicContact CG1-CG 4.47Å; V68-E72 WeakPolarHBondContact O-CB 3.29Å; V68-E72 WeakPolarHBondContact O-CG 3.4Å; V68-E72 PolarHBondContact O-N 3.28Å; E72-D75 PolarHBondContact O-N 3.27Å; E72-E76 WeakPolarHBondContact O-CG 3.31Å; E72-E76 PolarHBondContact O-N 2.94Å
73	E	56.8	Low	56.2	Low	128 Å²	128	110.6 Å²	110.6	60%	0.598	56%	0.562	S	S	*	*	H	α-helix	trans	-66.4	-38.3	174.3	-78.2	-178.4	178.7	0	0	112.3	E69 E76 E77	E69-E73 WeakPolarHBondContact O-CB 3.5Å; E69-E73 VanDerWaalsContact O-CG 3.3Å; E69-E73 WeakPolarHBondContact O-CG 3.3Å; E69-E73 PolarHBondContact O-N 2.81Å; E73-E76 PolarHBondContact O-N 3.37Å; E73-E77 WeakPolarHBondContact O-CB 3.34Å; E73-E77 PolarHBondContact O-N 3.2Å
74	E	55.7	Low	57.9	Low	98 Å²	98	104.7 Å²	104.7	46%	0.458	54%	0.543	S	S	.	.	H	α-helix	trans	-67.5	-40.4	175.5	-76.4	171	-157	0	0	111.5	N70 E71 E77 M78	N70-E74 PolarHBondContact ND2-OE1 3.21Å; N70-E74 VanDerWaalsContact O-CB 3.27Å; N70-E74 WeakPolarHBondContact O-CB 3.32Å; N70-E74 WeakPolarHBondContact O-CG 3.3Å; N70-E74 PolarHBondContact O-N 3.5Å; E71-E74 PolarHBondContact O-N 2.95Å; E74-E77 PolarHBondContact O-N 2.83Å; E74-M78 HydrophobicContact CB-CE 4.44Å; E74-M78 VanDerWaalsContact O-CB 3.27Å; E74-M78 WeakPolarHBondContact O-CB 3.49Å; E74-M78 WeakPolarHBondContact O-CE 3.43Å; E74-M78 WeakPolarHBondContact O-CG 3.44Å; E74-M78 PolarHBondContact O-N 2.89Å
75	D	57.1	Low	59.6	Low	93 Å²	93	105.9 Å²	105.9	50%	0.497	54%	0.539	S	S	.	.	H	α-helix	trans	-64.6	-39.6	174.5	-75.5	-24.1	0	0	0	112.3	E71 E72 M78 T79	E71-D75 WeakPolarHBondContact O-CB 3.43Å; E71-D75 VanDerWaalsContact O-CG 3.25Å; E71-D75 PolarHBondContact O-N 3.09Å; E72-D75 PolarHBondContact O-N 3.27Å; D75-M78 WeakPolarHBondContact OD1-CE 3.14Å; D75-T79 VanDerWaalsContact O-CG2 3.23Å; D75-T79 WeakPolarHBondContact O-CG2 3.44Å; D75-T79 PolarHBondContact O-N 3.38Å; D75-T79 PolarHBondContact O-OG1 2.86Å; D75-T79 VanDerWaalsContact O-OG1 3.13Å
76	E	61.3	Low	60.7	Low	140 Å²	140	103.6 Å²	103.6	65%	0.654	51%	0.514	S	S	*	.	H	α-helix	trans	-67	-41.9	173.3	-74.5	-170.1	174.1	0	0	112.4	E72 E73 T79 L80	E72-E76 WeakPolarHBondContact O-CG 3.31Å; E72-E76 PolarHBondContact O-N 2.94Å; E73-E76 PolarHBondContact O-N 3.37Å; E76-T79 WeakPolarHBondContact CA-OG1 3.48Å; E76-T79 PolarHBondContact O-N 2.88Å; E76-T79 PolarHBondContact O-OG1 3.32Å; E76-L80 PolarHBondContact O-N 3.34Å; E76-L80 VanDerWaalsContact O-N 3.11Å
77	E	60.1	Low	62.4	Low	135 Å²	135	96.2 Å²	96.2	63%	0.631	49%	0.491	S	S	*	.	H	α-helix	trans	-65.5	-41	176.3	-169.6	-179.2	163.4	0	0	111.5	E73 E74 L80 K81	E73-E77 WeakPolarHBondContact O-CB 3.34Å; E73-E77 PolarHBondContact O-N 3.2Å; E74-E77 PolarHBondContact O-N 2.83Å; E77-L80 PolarHBondContact O-N 2.98Å; E77-K81 WeakPolarHBondContact O-CB 3.36Å; E77-K81 PolarHBondContact O-N 3.33Å
78	M	56.7	Low	64	Low	81 Å²	81	97.5 Å²	97.5	40%	0.399	49%	0.494	S	S	.	.	H	α-helix	trans	-59.9	-55.3	174.9	-78.5	-171.2	-65.9	0	0	110.3	E74 D75 L80 K81 Y82	E74-M78 HydrophobicContact CB-CE 4.44Å; E74-M78 VanDerWaalsContact O-CB 3.27Å; E74-M78 WeakPolarHBondContact O-CB 3.49Å; E74-M78 WeakPolarHBondContact O-CE 3.43Å; E74-M78 WeakPolarHBondContact O-CG 3.44Å; E74-M78 PolarHBondContact O-N 2.89Å; D75-M78 WeakPolarHBondContact OD1-CE 3.14Å; M78-L80 VanDerWaalsContact C-N 3.26Å; M78-L80 PolarHBondContact O-N 2.92Å; M78-K81 PolarHBondContact O-N 3.37Å; M78-K81 VanDerWaalsContact O-N 3.09Å; M78-Y82 VanDerWaalsContact C-CD2 3.43Å; M78-Y82 HydrophobicContact CB-CD2 4.21Å; M78-Y82 HydrophobicContact CB-CE2 3.89Å; M78-Y82 HydrophobicContact CG-CE2 4.37Å; M78-Y82 WeakPolarHBondContact O-CD2 3.21Å; M78-Y82 PolarHBondContact O-N 3.47Å
79	T	64.7	Low	65.4	Low	98 Å²	98	96.7 Å²	96.7	60%	0.601	49%	0.486	S	S	*	.	H	α-helix	trans	-56.8	-37.2	-179.8	56.5	0	0	0	0	113.2	D75 E76 G83	D75-T79 VanDerWaalsContact O-CG2 3.23Å; D75-T79 WeakPolarHBondContact O-CG2 3.44Å; D75-T79 PolarHBondContact O-N 3.38Å; D75-T79 PolarHBondContact O-OG1 2.86Å; D75-T79 VanDerWaalsContact O-OG1 3.13Å; E76-T79 WeakPolarHBondContact CA-OG1 3.48Å; E76-T79 PolarHBondContact O-N 2.88Å; E76-T79 PolarHBondContact O-OG1 3.32Å; T79-G83 PolarHBondContact O-N 2.91Å
80	L	66.2	Low	66.9	Low	138 Å²	138	90.7 Å²	90.7	72%	0.723	46%	0.458	S	S	*	.	H	α-helix	trans	-69.4	-41.8	177	-154	110.2	0	0	0	112.5	E76 E77 M78 G83 A84	E76-L80 PolarHBondContact O-N 3.34Å; E76-L80 VanDerWaalsContact O-N 3.11Å; E77-L80 PolarHBondContact O-N 2.98Å; M78-L80 VanDerWaalsContact C-N 3.26Å; M78-L80 PolarHBondContact O-N 2.92Å; L80-G83 PolarHBondContact O-N 3.3Å; L80-A84 PolarHBondContact O-N 2.86Å
81	K	68.3	Low	68.7	Low	151 Å²	151	88.4 Å²	88.4	66%	0.657	44%	0.444	S	S	*	.	H	α-helix	trans	-66.8	-39.1	178.2	-169.6	174.9	-178.3	179.2	0	111.9	E77 M78 A84 K85	E77-K81 WeakPolarHBondContact O-CB 3.36Å; E77-K81 PolarHBondContact O-N 3.33Å; M78-K81 PolarHBondContact O-N 3.37Å; M78-K81 VanDerWaalsContact O-N 3.09Å; K81-A84 PolarHBondContact O-N 3.15Å; K81-K85 WeakPolarHBondContact O-CB 3.29Å; K81-K85 PolarHBondContact O-N 3.36Å
82	Y	64.5	Low	70.4	Confident	85 Å²	85	87.5 Å²	87.5	33%	0.333	45%	0.445	S	S	.	.	H	α-helix	trans	-64.7	-45.6	172.3	-70.6	-71.1	0	0	0	110.9	M78 A84 K85 H86 E384	M78-Y82 VanDerWaalsContact C-CD2 3.43Å; M78-Y82 HydrophobicContact CB-CD2 4.21Å; M78-Y82 HydrophobicContact CB-CE2 3.89Å; M78-Y82 HydrophobicContact CG-CE2 4.37Å; M78-Y82 WeakPolarHBondContact O-CD2 3.21Å; M78-Y82 PolarHBondContact O-N 3.47Å; Y82-A84 PolarHBondContact O-N 3.49Å; Y82-K85 PolarHBondContact O-N 2.8Å; Y82-H86 PolarHBondContact O-CD2 3Å; Y82-H86 PolarHBondContact O-N 2.89Å; Y82-E384 HydrophobicContact CE1-CG 4.08Å; Y82-E384 WeakPolarHBondContact CE1-OE1 3.36Å; Y82-E384 PolarHBondContact OH-OE1 3.32Å
83	G	71	Confident	72	Confident	35 Å²	35	82.1 Å²	82.1	36%	0.361	42%	0.421	S	S	.	.	H	α-helix	trans	-53.8	-49.4	173.9	0	0	0	0	0	112.7	T79 L80 K85 H86 V87	T79-G83 PolarHBondContact O-N 2.91Å; L80-G83 PolarHBondContact O-N 3.3Å; G83-K85 PolarHBondContact O-N 3.14Å; G83-H86 PolarHBondContact O-N 3.02Å; G83-V87 WeakPolarHBondContact O-CG2 3.12Å; G83-V87 PolarHBondContact O-N 3.48Å
84	A	77.2	Confident	73.7	Confident	50 Å²	50	76.1 Å²	76.1	41%	0.413	39%	0.393	S	S	.	.	H	α-helix	trans	-63.7	-41.2	178.5	0	0	0	0	0	112.9	L80 K81 Y82 V87 I88	L80-A84 PolarHBondContact O-N 2.86Å; K81-A84 PolarHBondContact O-N 3.15Å; Y82-A84 PolarHBondContact O-N 3.49Å; A84-V87 PolarHBondContact O-N 3.36Å; A84-I88 WeakPolarHBondContact O-CG1 3.24Å; A84-I88 PolarHBondContact O-N 3.27Å
85	K	78.2	Confident	75.6	Confident	117 Å²	117	73.3 Å²	73.3	51%	0.509	38%	0.382	S	S	.	.	H	α-helix	trans	-62.1	-43.6	176	-175	-178.7	176.8	-171.8	0	111.4	K81 Y82 G83 I88 M89	K81-K85 WeakPolarHBondContact O-CB 3.29Å; K81-K85 PolarHBondContact O-N 3.36Å; Y82-K85 PolarHBondContact O-N 2.8Å; G83-K85 PolarHBondContact O-N 3.14Å; K85-I88 PolarHBondContact O-N 3.3Å; K85-M89 HydrophobicContact CD-CE 4.32Å; K85-M89 HydrophobicContact CG-CE 3.99Å; K85-M89 VanDerWaalsContact O-CG 3.3Å; K85-M89 WeakPolarHBondContact O-CG 3.18Å; K85-M89 PolarHBondContact O-N 3.06Å
86	H	73.9	Confident	77.4	Confident	35 Å²	35	73 Å²	73	16%	0.162	38%	0.38	C	S	.	.	H	α-helix	trans	-64.3	-40.2	175.9	-74.2	-64.9	0	0	0	112.4	Y82 G83 M89 L90 V388	Y82-H86 PolarHBondContact O-CD2 3Å; Y82-H86 PolarHBondContact O-N 2.89Å; G83-H86 PolarHBondContact O-N 3.02Å; H86-M89 PolarHBondContact O-N 3.23Å; H86-L90 PolarHBondContact O-N 2.66Å; H86-V388 HydrophobicContact CB-CG2 4.13Å
87	V	80.9	Confident	79	Confident	43 Å²	43	66.3 Å²	66.3	26%	0.261	35%	0.349	S	S	.	.	H	α-helix	trans	-59.2	-51.4	174.1	173.7	0	0	0	0	110.1	G83 A84 M89 L90 F91 L431	G83-V87 WeakPolarHBondContact O-CG2 3.12Å; G83-V87 PolarHBondContact O-N 3.48Å; A84-V87 PolarHBondContact O-N 3.36Å; V87-M89 VanDerWaalsContact C-N 3.3Å; V87-M89 PolarHBondContact O-N 3.08Å; V87-L90 PolarHBondContact O-N 3.31Å; V87-F91 HydrophobicContact CG1-CD2 3.69Å; V87-F91 HydrophobicContact CG1-CE2 3.55Å; V87-F91 HydrophobicContact CG1-CZ 4.35Å; V87-F91 WeakPolarHBondContact O-CD2 3.38Å; V87-F91 PolarHBondContact O-N 3.32Å; V87-L431 HydrophobicContact CB-CD1 4.12Å; V87-L431 HydrophobicContact CG1-CD1 3.95Å; V87-L431 HydrophobicContact CG2-CD1 3.71Å
88	I	82.7	Confident	80.7	Confident	106 Å²	106	60 Å²	60	54%	0.544	32%	0.319	S	S	.	.	H	α-helix	trans	-60.2	-40.4	-179.9	-67.5	167.2	0	0	0	111.3	A84 K85 L90 F91 V92	A84-I88 WeakPolarHBondContact O-CG1 3.24Å; A84-I88 PolarHBondContact O-N 3.27Å; K85-I88 PolarHBondContact O-N 3.3Å; I88-L90 PolarHBondContact O-N 3.39Å; I88-F91 PolarHBondContact O-N 2.88Å; I88-F91 VanDerWaalsContact O-N 3.17Å; I88-V92 HydrophobicContact CG2-CG2 4.11Å; I88-V92 WeakPolarHBondContact O-CG2 3.41Å; I88-V92 PolarHBondContact O-N 3.33Å; I88-V92 VanDerWaalsContact O-N 3.1Å
89	M	82.6	Confident	82.6	Confident	62 Å²	62	60.1 Å²	60.1	31%	0.305	32%	0.324	S	S	.	.	H	α-helix	trans	-61.8	-24.2	177.2	-75.9	-178.6	175.3	0	0	113.9	K85 H86 V87 P93	K85-M89 HydrophobicContact CD-CE 4.32Å; K85-M89 HydrophobicContact CG-CE 3.99Å; K85-M89 VanDerWaalsContact O-CG 3.3Å; K85-M89 WeakPolarHBondContact O-CG 3.18Å; K85-M89 PolarHBondContact O-N 3.06Å; H86-M89 PolarHBondContact O-N 3.23Å; V87-M89 VanDerWaalsContact C-N 3.3Å; V87-M89 PolarHBondContact O-N 3.08Å; M89-P93 WeakPolarHBondContact O-CD 3.26Å; M89-P93 WeakPolarHBondContact O-CG 3.5Å
90	L	83.3	Confident	84.1	Confident	1 Å²	1	57 Å²	57	1%	0.005	31%	0.305	C	S	.	.	H	α-helix	trans	-87	-37.4	172.3	-65.5	175.1	0	0	0	112.6	H86 V87 I88 P93 V94 V388 L390 L431	H86-L90 PolarHBondContact O-N 2.66Å; V87-L90 PolarHBondContact O-N 3.31Å; I88-L90 PolarHBondContact O-N 3.39Å; L90-P93 VanDerWaalsContact O-CD 3.29Å; L90-P93 WeakPolarHBondContact O-CD 3.45Å; L90-P93 VanDerWaalsContact O-CG 3.32Å; L90-P93 WeakPolarHBondContact O-CG 3.32Å; L90-V94 VanDerWaalsContact O-CG2 3.27Å; L90-V94 WeakPolarHBondContact O-CG2 3.4Å; L90-V94 PolarHBondContact O-N 3.09Å; L90-V388 HydrophobicContact CD1-CB 3.93Å; L90-V388 HydrophobicContact CD1-CG1 3.64Å; L90-V388 HydrophobicContact CD2-CB 4.26Å; L90-V388 HydrophobicContact CD2-CG1 4.3Å; L90-V388 HydrophobicContact CG-CB 4.35Å; L90-V388 HydrophobicContact CG-CG1 4.46Å; L90-L390 HydrophobicContact CD2-CB 4.19Å; L90-L431 HydrophobicContact CD1-CD1 4.02Å; L90-L431 HydrophobicContact CD1-CD2 3.92Å
91	F	89	Confident	85.5	Confident	35 Å²	35	50.4 Å²	50.4	15%	0.154	27%	0.271	C	S	.	.	H	α-helix	trans	-66.2	-43.8	-176.8	-90.2	-121.2	0	0	0	112.7	V87 I88 V94 T95 L424 L427 C428 L431	V87-F91 HydrophobicContact CG1-CD2 3.69Å; V87-F91 HydrophobicContact CG1-CE2 3.55Å; V87-F91 HydrophobicContact CG1-CZ 4.35Å; V87-F91 WeakPolarHBondContact O-CD2 3.38Å; V87-F91 PolarHBondContact O-N 3.32Å; I88-F91 PolarHBondContact O-N 2.88Å; I88-F91 VanDerWaalsContact O-N 3.17Å; F91-V94 PolarHBondContact O-N 3.33Å; F91-T95 VanDerWaalsContact O-CB 3.23Å; F91-T95 WeakPolarHBondContact O-CB 3.41Å; F91-T95 PolarHBondContact O-N 3.5Å; F91-T95 PolarHBondContact O-OG1 2.88Å; F91-L424 HydrophobicContact CD1-CD1 4.47Å; F91-L424 HydrophobicContact CD1-CD2 3.81Å; F91-L424 HydrophobicContact CE1-CB 3.91Å; F91-L424 HydrophobicContact CE1-CD2 3.85Å; F91-L424 HydrophobicContact CE1-CG 4.29Å; F91-L424 WeakPolarHBondContact CZ-O 3.32Å; F91-L427 HydrophobicContact CD2-CD2 3.93Å; F91-L427 HydrophobicContact CE2-CB 4.29Å; F91-L427 HydrophobicContact CE2-CD2 3.32Å; F91-L427 HydrophobicContact CE2-CG 4.28Å; F91-L427 HydrophobicContact CZ-CB 4.17Å; F91-L427 HydrophobicContact CZ-CD2 4.07Å; F91-C428 HydrophobicContact CZ-CB 4.18Å; F91-C428 WeakPolarHBondContact CZ-SG 3.41Å; F91-L431 HydrophobicContact CE2-CD1 4.18Å
92	V	91.1	Very high	86.8	Confident	88 Å²	88	43.9 Å²	43.9	53%	0.533	24%	0.243	S	C	.	.	H	α-helix	trans	-56.7	-55.2	-177.8	172.2	0	0	0	0	112.6	I88 V94 T95 L96	I88-V92 HydrophobicContact CG2-CG2 4.11Å; I88-V92 WeakPolarHBondContact O-CG2 3.41Å; I88-V92 PolarHBondContact O-N 3.33Å; I88-V92 VanDerWaalsContact O-N 3.1Å; V92-V94 PolarHBondContact O-N 2.83Å; V92-T95 PolarHBondContact O-N 3.43Å; V92-L96 WeakPolarHBondContact O-CB 3.41Å; V92-L96 PolarHBondContact O-N 3.16Å
93	P	91.4	Very high	88.3	Confident	6 Å²	6	42.2 Å²	42.2	4%	0.039	25%	0.247	C	C	.	.	H	α-helix	trans	-67.9	-35.1	-177.8	29.4	-39	0	0	0	112.8	M89 L90 L96 C97 I233 Y294 F395	M89-P93 WeakPolarHBondContact O-CD 3.26Å; M89-P93 WeakPolarHBondContact O-CG 3.5Å; L90-P93 VanDerWaalsContact O-CD 3.29Å; L90-P93 WeakPolarHBondContact O-CD 3.45Å; L90-P93 VanDerWaalsContact O-CG 3.32Å; L90-P93 WeakPolarHBondContact O-CG 3.32Å; P93-L96 PolarHBondContact O-N 3.12Å; P93-C97 WeakPolarHBondContact O-CB 3.36Å; P93-C97 PolarHBondContact O-N 2.85Å; P93-I233 HydrophobicContact CB-CD1 3.64Å; P93-I233 HydrophobicContact CB-CG1 4.09Å; P93-Y294 HydrophobicContact CB-CE1 4.17Å; P93-Y294 HydrophobicContact CB-CE2 4.04Å; P93-Y294 VanDerWaalsContact CB-OH 3.26Å; P93-Y294 WeakPolarHBondContact CB-OH 3.37Å; P93-Y294 HydrophobicContact CG-CE1 3.72Å; P93-Y294 HydrophobicContact CG-CE2 4.48Å; P93-Y294 WeakPolarHBondContact CG-OH 3.45Å; P93-F395 HydrophobicContact CB-CE1 3.95Å; P93-F395 HydrophobicContact CB-CZ 4.38Å; P93-F395 HydrophobicContact CG-CE1 4.29Å; P93-F395 HydrophobicContact CG-CZ 4.32Å
94	V	92.4	Very high	89.4	Confident	1 Å²	1	40.7 Å²	40.7	1%	0.006	23%	0.231	C	C	.	.	H	α-helix	trans	-64.6	-46.9	175.9	172	0	0	0	0	110.5	L90 F91 V92 L96 C97 M98 L390 F395 Y398 L427	L90-V94 VanDerWaalsContact O-CG2 3.27Å; L90-V94 WeakPolarHBondContact O-CG2 3.4Å; L90-V94 PolarHBondContact O-N 3.09Å; F91-V94 PolarHBondContact O-N 3.33Å; V92-V94 PolarHBondContact O-N 2.83Å; V94-L96 VanDerWaalsContact C-N 3.35Å; V94-L96 PolarHBondContact O-N 2.91Å; V94-C97 WeakPolarHBondContact O-CB 3.28Å; V94-C97 PolarHBondContact O-N 2.67Å; V94-M98 HydrophobicContact CG1-CE 3.49Å; V94-M98 VanDerWaalsContact CG1-CE 3.49Å; V94-M98 HydrophobicContact CG1-SD 4.27Å; V94-M98 WeakPolarHBondContact O-CG 3.33Å; V94-M98 PolarHBondContact O-N 3.39Å; V94-L390 HydrophobicContact CG2-CD2 4.03Å; V94-F395 HydrophobicContact CB-CE1 4.31Å; V94-F395 HydrophobicContact CG2-CD1 3.98Å; V94-F395 HydrophobicContact CG2-CD2 4.5Å; V94-F395 HydrophobicContact CG2-CE1 3.55Å; V94-F395 HydrophobicContact CG2-CE2 4.14Å; V94-F395 HydrophobicContact CG2-CG 4.43Å; V94-F395 HydrophobicContact CG2-CZ 3.64Å; V94-Y398 HydrophobicContact CG1-CD2 3.88Å; V94-L427 HydrophobicContact CG1-CD1 4.43Å; V94-L427 HydrophobicContact CG2-CD1 4.38Å
95	T	94.6	Very high	90.2	Very high	39 Å²	39	38.6 Å²	38.6	24%	0.239	21%	0.213	C	C	.	.	H	α-helix	trans	-60.1	-45.7	176.5	-62.5	0	0	0	0	111.1	F91 V92 C97 M98 V99 F420	F91-T95 VanDerWaalsContact O-CB 3.23Å; F91-T95 WeakPolarHBondContact O-CB 3.41Å; F91-T95 PolarHBondContact O-N 3.5Å; F91-T95 PolarHBondContact O-OG1 2.88Å; V92-T95 PolarHBondContact O-N 3.43Å; T95-C97 VanDerWaalsContact C-N 3.32Å; T95-C97 PolarHBondContact O-N 3.36Å; T95-M98 PolarHBondContact O-N 3.38Å; T95-V99 HydrophobicContact CG2-CG2 4.32Å; T95-V99 VanDerWaalsContact O-CG2 3.3Å; T95-V99 WeakPolarHBondContact O-CG2 3.24Å; T95-V99 PolarHBondContact O-N 3.46Å; T95-F420 HydrophobicContact CG2-CE2 3.85Å; T95-F420 HydrophobicContact CG2-CZ 3.59Å
96	L	95.2	Very high	90.8	Very high	87 Å²	87	36.3 Å²	36.3	46%	0.455	20%	0.203	S	C	.	.	H	α-helix	trans	-60.3	-43.4	178.1	-163.2	154.5	0	0	0	111.1	V92 P93 V94 V99 V100 I233	V92-L96 WeakPolarHBondContact O-CB 3.41Å; V92-L96 PolarHBondContact O-N 3.16Å; P93-L96 PolarHBondContact O-N 3.12Å; V94-L96 VanDerWaalsContact C-N 3.35Å; V94-L96 PolarHBondContact O-N 2.91Å; L96-V99 PolarHBondContact O-N 2.91Å; L96-V100 HydrophobicContact CD2-CG2 3.92Å; L96-V100 VanDerWaalsContact O-CG2 3.32Å; L96-V100 WeakPolarHBondContact O-CG2 3.48Å; L96-V100 PolarHBondContact O-N 3.2Å; L96-I233 HydrophobicContact CD2-CD1 4.46Å; L96-I233 HydrophobicContact CD2-CG2 3.72Å
97	C	95.9	Very high	91.6	Very high	0 Å²	0	36.9 Å²	36.9	0%	0	21%	0.211	C	C	.	.	H	α-helix	trans	-59.3	-47.4	175.8	-167.2	0	0	0	0	112.2	P93 V94 T95 V100 V101 I233 S236 F395 S399	P93-C97 WeakPolarHBondContact O-CB 3.36Å; P93-C97 PolarHBondContact O-N 2.85Å; V94-C97 WeakPolarHBondContact O-CB 3.28Å; V94-C97 PolarHBondContact O-N 2.67Å; T95-C97 VanDerWaalsContact C-N 3.32Å; T95-C97 PolarHBondContact O-N 3.36Å; C97-V100 PolarHBondContact O-N 2.88Å; C97-V101 WeakPolarHBondContact O-CG2 3.34Å; C97-V101 PolarHBondContact O-N 3.36Å; C97-V101 VanDerWaalsContact O-N 3.12Å; C97-I233 HydrophobicContact CB-CG2 3.73Å; C97-S236 PolarHBondContact SG-OG 2.97Å; C97-F395 HydrophobicContact CB-CD1 4.11Å; C97-S399 PolarHBondContact SG-OG 3.25Å
98	M	95.5	Very high	92.2	Very high	2 Å²	2	34.9 Å²	34.9	1%	0.01	20%	0.199	C	C	.	.	H	α-helix	trans	-60.5	-45.4	176.3	-67.6	170	178.9	0	0	111.9	V94 T95 V100 V101 V102 Y398 S399 V402 F420 I423	V94-M98 HydrophobicContact CG1-CE 3.49Å; V94-M98 VanDerWaalsContact CG1-CE 3.49Å; V94-M98 HydrophobicContact CG1-SD 4.27Å; V94-M98 WeakPolarHBondContact O-CG 3.33Å; V94-M98 PolarHBondContact O-N 3.39Å; T95-M98 PolarHBondContact O-N 3.38Å; M98-V100 PolarHBondContact O-N 2.88Å; M98-V101 PolarHBondContact O-N 3.46Å; M98-V102 WeakPolarHBondContact O-CG2 3.49Å; M98-V102 PolarHBondContact O-N 2.98Å; M98-Y398 HydrophobicContact CE-CD2 4.41Å; M98-Y398 HydrophobicContact CE-CG 4.14Å; M98-S399 PolarHBondContact N-OG 3.31Å; M98-V402 HydrophobicContact CB-CG1 4Å; M98-V402 HydrophobicContact CG-CG1 3.97Å; M98-F420 HydrophobicContact CB-CD2 4.23Å; M98-F420 HydrophobicContact CB-CE2 4.27Å; M98-F420 HydrophobicContact SD-CD2 3.44Å; M98-F420 WeakPolarHBondContact SD-CD2 3.22Å; M98-F420 HydrophobicContact SD-CE2 3.55Å; M98-F420 VanDerWaalsContact SD-CE2 3.55Å; M98-I423 HydrophobicContact CE-CB 3.95Å; M98-I423 HydrophobicContact CE-CD1 4.05Å; M98-I423 HydrophobicContact CE-CG2 3.36Å
99	V	96.1	Very high	92.4	Very high	83 Å²	83	32.3 Å²	32.3	50%	0.503	19%	0.19	S	C	.	.	H	α-helix	trans	-61.1	-45.3	179	169.8	0	0	0	0	111	T95 L96 V101 V102 A103	T95-V99 HydrophobicContact CG2-CG2 4.32Å; T95-V99 VanDerWaalsContact O-CG2 3.3Å; T95-V99 WeakPolarHBondContact O-CG2 3.24Å; T95-V99 PolarHBondContact O-N 3.46Å; L96-V99 PolarHBondContact O-N 2.91Å; V99-V101 VanDerWaalsContact C-N 3.32Å; V99-V101 PolarHBondContact O-N 2.86Å; V99-V102 PolarHBondContact O-N 3.23Å; V99-A103 WeakPolarHBondContact O-CB 3.39Å; V99-A103 PolarHBondContact O-N 3.39Å
100	V	96.4	Very high	92.7	Very high	33 Å²	33	30.9 Å²	30.9	20%	0.2	18%	0.182	C	C	.	.	H	α-helix	trans	-58.6	-44.3	176.9	169.7	0	0	0	0	111.2	L96 C97 M98 T104 M234 A237	L96-V100 HydrophobicContact CD2-CG2 3.92Å; L96-V100 VanDerWaalsContact O-CG2 3.32Å; L96-V100 WeakPolarHBondContact O-CG2 3.48Å; L96-V100 PolarHBondContact O-N 3.2Å; C97-V100 PolarHBondContact O-N 2.88Å; M98-V100 PolarHBondContact O-N 2.88Å; V100-T104 WeakPolarHBondContact O-CB 3.48Å; V100-T104 PolarHBondContact O-N 3.48Å; V100-T104 PolarHBondContact O-OG1 2.89Å; V100-M234 HydrophobicContact CG1-SD 4.36Å; V100-A237 HydrophobicContact CB-CB 4.47Å; V100-A237 HydrophobicContact CG1-CB 3.91Å
101	V	96.6	Very high	93	Very high	0 Å²	0	31.6 Å²	31.6	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-67.8	-48.6	178.7	173	0	0	0	0	111.4	C97 M98 V99 A103 T104 I105 A237 A240 L241 I244	C97-V101 WeakPolarHBondContact O-CG2 3.34Å; C97-V101 PolarHBondContact O-N 3.36Å; C97-V101 VanDerWaalsContact O-N 3.12Å; M98-V101 PolarHBondContact O-N 3.46Å; V99-V101 VanDerWaalsContact C-N 3.32Å; V99-V101 PolarHBondContact O-N 2.86Å; V101-A103 PolarHBondContact O-N 3.14Å; V101-T104 PolarHBondContact O-N 3.35Å; V101-I105 HydrophobicContact CG1-CG1 4.29Å; V101-I105 WeakPolarHBondContact O-CG1 3.38Å; V101-I105 PolarHBondContact O-N 2.7Å; V101-A237 HydrophobicContact CG2-CB 3.66Å; V101-A240 HydrophobicContact CG2-CB 4.15Å; V101-L241 HydrophobicContact CG1-CD2 4.11Å; V101-L241 HydrophobicContact CG2-CG 4.39Å; V101-I244 HydrophobicContact CG1-CD1 3.65Å
102	V	94.9	Very high	92.8	Very high	13 Å²	13	32.8 Å²	32.8	8%	0.079	20%	0.195	C	C	.	.	H	α-helix	trans	-60.9	-46.3	179	172.3	0	0	0	0	111.1	M98 V99 T104 I105 K106 V402 W413 T416	M98-V102 WeakPolarHBondContact O-CG2 3.49Å; M98-V102 PolarHBondContact O-N 2.98Å; V99-V102 PolarHBondContact O-N 3.23Å; V102-T104 VanDerWaalsContact C-N 3.29Å; V102-T104 PolarHBondContact O-N 3.32Å; V102-I105 PolarHBondContact O-N 2.97Å; V102-K106 HydrophobicContact CG1-CG 4.44Å; V102-K106 WeakPolarHBondContact O-CG 3.39Å; V102-K106 PolarHBondContact O-N 3.14Å; V102-V402 HydrophobicContact CG2-CB 4.45Å; V102-V402 HydrophobicContact CG2-CG1 4.01Å; V102-V402 HydrophobicContact CG2-CG2 3.73Å; V102-W413 HydrophobicContact CG1-CH2 4.43Å; V102-W413 HydrophobicContact CG1-CZ3 4.05Å; V102-T416 HydrophobicContact CG1-CG2 3.99Å; V102-T416 HydrophobicContact CG2-CG2 3.9Å
103	A	94.6	Very high	92.4	Very high	50 Å²	50	33.9 Å²	33.9	41%	0.413	19%	0.193	S	C	.	.	H	α-helix	trans	-60.2	-40.7	177	0	0	0	0	0	111.5	V99 V101 K106 S107	V99-A103 WeakPolarHBondContact O-CB 3.39Å; V99-A103 PolarHBondContact O-N 3.39Å; V101-A103 PolarHBondContact O-N 3.14Å; A103-K106 PolarHBondContact O-N 2.95Å; A103-S107 WeakPolarHBondContact O-CB 3.4Å; A103-S107 PolarHBondContact O-N 3.09Å; A103-S107 PolarHBondContact O-OG 3.36Å
104	T	94.9	Very high	91.5	Very high	4 Å²	4	39 Å²	39	3%	0.025	22%	0.22	C	C	.	.	H	α-helix	trans	-65	-47.5	175.7	-61	0	0	0	0	111.5	V100 V101 V102 K106 S107 V108 Y111 Y187 L241	V100-T104 WeakPolarHBondContact O-CB 3.48Å; V100-T104 PolarHBondContact O-N 3.48Å; V100-T104 PolarHBondContact O-OG1 2.89Å; V101-T104 PolarHBondContact O-N 3.35Å; V102-T104 VanDerWaalsContact C-N 3.29Å; V102-T104 PolarHBondContact O-N 3.32Å; T104-K106 VanDerWaalsContact C-N 3.26Å; T104-K106 PolarHBondContact O-N 3.49Å; T104-S107 PolarHBondContact O-N 3.22Å; T104-S107 PolarHBondContact O-OG 2.93Å; T104-V108 HydrophobicContact CG2-CB 4.32Å; T104-V108 HydrophobicContact CG2-CG2 4.33Å; T104-V108 WeakPolarHBondContact O-CB 3.49Å; T104-V108 PolarHBondContact O-N 3.48Å; T104-Y111 HydrophobicContact CG2-CD2 3.84Å; T104-Y111 HydrophobicContact CG2-CE2 3.79Å; T104-Y187 HydrophobicContact CG2-CD2 4.32Å; T104-Y187 HydrophobicContact CG2-CE2 3.62Å; T104-Y187 PolarHBondContact OG1-OH 3.13Å; T104-L241 HydrophobicContact CG2-CD1 3.74Å; T104-L241 HydrophobicContact CG2-CD2 3.71Å; T104-L241 HydrophobicContact CG2-CG 4.4Å
105	I	93.4	Very high	90.2	Very high	6 Å²	6	43.5 Å²	43.5	3%	0.031	24%	0.244	C	C	.	.	H	α-helix	trans	-59.9	-38.2	179	-68.2	-56	0	0	0	111.5	V101 V102 Y111 T112 L241 I244 A407	V101-I105 HydrophobicContact CG1-CG1 4.29Å; V101-I105 WeakPolarHBondContact O-CG1 3.38Å; V101-I105 PolarHBondContact O-N 2.7Å; V102-I105 PolarHBondContact O-N 2.97Å; I105-Y111 VanDerWaalsContact CD1-CB 3.45Å; I105-Y111 HydrophobicContact CD1-CG 4.23Å; I105-T112 HydrophobicContact CG2-CG2 3.88Å; I105-L241 HydrophobicContact CD1-CD2 3.66Å; I105-L241 HydrophobicContact CG1-CD2 4.09Å; I105-I244 HydrophobicContact CD1-CB 4.37Å; I105-I244 HydrophobicContact CD1-CD1 4.11Å; I105-I244 HydrophobicContact CD1-CG2 3.65Å; I105-I244 HydrophobicContact CG1-CD1 4.24Å; I105-A407 HydrophobicContact CG2-CB 3.83Å
106	K	91	Very high	88.7	Confident	69 Å²	69	44.2 Å²	44.2	30%	0.3	26%	0.259	S	S	.	.	H	α-helix	trans	-75.4	-36.9	178.6	-68.4	-60	-166.7	-162.3	0	113.4	V102 A103 T104 S406 G411 W413	V102-K106 HydrophobicContact CG1-CG 4.44Å; V102-K106 WeakPolarHBondContact O-CG 3.39Å; V102-K106 PolarHBondContact O-N 3.14Å; A103-K106 PolarHBondContact O-N 2.95Å; T104-K106 VanDerWaalsContact C-N 3.26Å; T104-K106 PolarHBondContact O-N 3.49Å; K106-S406 WeakPolarHBondContact CE-OG 3.15Å; K106-S406 PolarHBondContact NZ-O 3.2Å; K106-S406 VanDerWaalsContact NZ-O 3.08Å; K106-S406 PolarHBondContact NZ-OG 2.9Å; K106-G411 VanDerWaalsContact NZ-CA 3.27Å; K106-G411 PolarHBondContact NZ-O 2.99Å; K106-W413 HydrophobicContact CD-CZ2 4.49Å; K106-W413 HydrophobicContact CG-CH2 4.15Å; K106-W413 HydrophobicContact CG-CZ2 4.12Å
107	S	92.2	Very high	87.3	Confident	47 Å²	47	45.8 Å²	45.8	33%	0.329	26%	0.264	S	S	.	.	H	α-helix	trans	-81.8	-44.2	-178.6	53.3	0	0	0	0	112.2	A103 T104 T194	A103-S107 WeakPolarHBondContact O-CB 3.4Å; A103-S107 PolarHBondContact O-N 3.09Å; A103-S107 PolarHBondContact O-OG 3.36Å; T104-S107 PolarHBondContact O-N 3.22Å; T104-S107 PolarHBondContact O-OG 2.93Å; S107-T194 WeakPolarHBondContact O-CG2 3.17Å
108	V	92.9	Very high	86	Confident	1 Å²	1	51.5 Å²	51.5	1%	0.006	29%	0.285	C	S	.	.			trans	-104	98	-170	-177.7	0	0	0	0	111.1	T104 F110 Y111 E190 V191	T104-V108 HydrophobicContact CG2-CB 4.32Å; T104-V108 HydrophobicContact CG2-CG2 4.33Å; T104-V108 WeakPolarHBondContact O-CB 3.49Å; T104-V108 PolarHBondContact O-N 3.48Å; V108-F110 HydrophobicContact CG1-CB 4.04Å; V108-F110 PolarHBondContact O-N 3.41Å; V108-Y111 HydrophobicContact CB-CD2 4.01Å; V108-Y111 HydrophobicContact CB-CE2 4.35Å; V108-Y111 HydrophobicContact CG1-CD2 3.71Å; V108-Y111 HydrophobicContact CG1-CE2 3.87Å; V108-Y111 PolarHBondContact O-N 3.31Å; V108-E190 HydrophobicContact CG1-CB 4.17Å; V108-E190 HydrophobicContact CG1-CG 3.56Å; V108-V191 HydrophobicContact CG2-CG2 3.99Å
109	S	87.2	Confident	84.9	Confident	51 Å²	51	54 Å²	54	36%	0.357	30%	0.298	S	S	.	.	G	3₁₀ helix	trans	-61.8	-14.7	-176.9	71.6	0	0	0	0	115.5	Y111 T112 K113	S109-Y111 VanDerWaalsContact C-N 3.3Å; S109-Y111 PolarHBondContact O-N 2.94Å; S109-T112 PolarHBondContact O-N 2.84Å; S109-T112 PolarHBondContact O-OG1 2.99Å; S109-K113 WeakPolarHBondContact O-CG 3.39Å; S109-K113 PolarHBondContact O-N 3.27Å; S109-K113 PolarHBondContact OG-NZ 3.45Å
110	F	89.2	Confident	84	Confident	33 Å²	33	57.7 Å²	57.7	15%	0.145	31%	0.314	C	S	.	.	G	3₁₀ helix	trans	-62.4	-36.2	177.7	176.3	-100.7	0	0	0	113.4	V108 T112 K113 E190 K245	V108-F110 HydrophobicContact CG1-CB 4.04Å; V108-F110 PolarHBondContact O-N 3.41Å; F110-T112 PolarHBondContact O-N 3.23Å; F110-K113 PolarHBondContact O-N 2.91Å; F110-E190 VanDerWaalsContact CB-CD 3.45Å; F110-E190 HydrophobicContact CB-CG 3.24Å; F110-E190 VanDerWaalsContact CB-OE1 3.31Å; F110-E190 WeakPolarHBondContact CB-OE1 3.42Å; F110-E190 HydrophobicContact CD1-CG 3.81Å; F110-E190 HydrophobicContact CD2-CG 4.17Å; F110-E190 HydrophobicContact CG-CG 3.49Å; F110-E190 VanDerWaalsContact CG-CG 3.49Å; F110-K245 HydrophobicContact CD1-CD 3.98Å; F110-K245 HydrophobicContact CE1-CD 3.77Å; F110-K245 HydrophobicContact CE1-CG 4.22Å; F110-K245 HydrophobicContact CZ-CD 4.26Å; F110-K245 WeakPolarHBondContact O-CD 3.48Å; F110-K245 WeakPolarHBondContact O-CE 3.44Å
111	Y	88.4	Confident	83.1	Confident	16 Å²	16	61.3 Å²	61.3	6%	0.063	32%	0.324	C	S	.	.	G	3₁₀ helix	trans	-73.1	-15.9	-178.2	-69.8	-79.3	0	0	0	113.2	T104 I105 V108 S109 Y187 L241 K245	T104-Y111 HydrophobicContact CG2-CD2 3.84Å; T104-Y111 HydrophobicContact CG2-CE2 3.79Å; I105-Y111 VanDerWaalsContact CD1-CB 3.45Å; I105-Y111 HydrophobicContact CD1-CG 4.23Å; V108-Y111 HydrophobicContact CB-CD2 4.01Å; V108-Y111 HydrophobicContact CB-CE2 4.35Å; V108-Y111 HydrophobicContact CG1-CD2 3.71Å; V108-Y111 HydrophobicContact CG1-CE2 3.87Å; V108-Y111 PolarHBondContact O-N 3.31Å; S109-Y111 VanDerWaalsContact C-N 3.3Å; S109-Y111 PolarHBondContact O-N 2.94Å; Y111-Y187 HydrophobicContact CE2-CD2 4.33Å; Y111-L241 HydrophobicContact CD1-CB 3.99Å; Y111-L241 HydrophobicContact CD1-CD2 4.1Å; Y111-L241 HydrophobicContact CD2-CD2 4.44Å; Y111-L241 HydrophobicContact CE1-CB 3.68Å; Y111-L241 HydrophobicContact CE1-CD2 4.37Å; Y111-L241 HydrophobicContact CE1-CG 4.43Å; Y111-L241 HydrophobicContact CG-CD2 4.17Å; Y111-K245 HydrophobicContact CD1-CB 3.98Å; Y111-K245 HydrophobicContact CD1-CD 4.48Å
112	T	85.6	Confident	82.5	Confident	59 Å²	59	61.3 Å²	61.3	36%	0.362	33%	0.325	S	S	.	.	T	Hydrogen-bonded Turn	trans	-99.5	-15.7	176.2	61.5	0	0	0	0	113	I105 S109 F110 A407	I105-T112 HydrophobicContact CG2-CG2 3.88Å; S109-T112 PolarHBondContact O-N 2.84Å; S109-T112 PolarHBondContact O-OG1 2.99Å; F110-T112 PolarHBondContact O-N 3.23Å; T112-A407 HydrophobicContact CG2-CB 3.93Å
113	K	82.8	Confident	81.9	Confident	111 Å²	111	64 Å²	64	48%	0.483	34%	0.342	S	S	.	.			trans	-81.9	130.1	-179.9	-77.3	171	-179.8	166.1	0	112.4	S109 F110 D115 K245	S109-K113 WeakPolarHBondContact O-CG 3.39Å; S109-K113 PolarHBondContact O-N 3.27Å; S109-K113 PolarHBondContact OG-NZ 3.45Å; F110-K113 PolarHBondContact O-N 2.91Å; K113-D115 PolarHBondContact O-N 3.3Å; K113-K245 PolarHBondContact O-NZ 3.33Å
114	N	72.8	Confident	81.5	Confident	114 Å²	114	65.5 Å²	65.5	61%	0.61	34%	0.339	S	S	*	.			trans	-93.7	80.3	177.1	-66.4	-25.8	0	0	0	110.6	G116	N114-G116 PolarHBondContact O-N 3.32Å
115	D	64.9	Low	80.9	Confident	96 Å²	96	67.5 Å²	67.5	51%	0.513	35%	0.353	S	S	.	.			trans	-74.5	18.7	179.4	-64.6	-27.5	0	0	0	114.1	K113 Q117	K113-D115 PolarHBondContact O-N 3.3Å; D115-Q117 PolarHBondContact O-N 3.27Å
116	G	63.1	Low	80.2	Confident	53 Å²	53	68.3 Å²	68.3	55%	0.546	36%	0.356	S	S	.	.	S	Bend	trans	66.3	0.1	-176.7	0	0	0	0	0	115.2	N114 R118	N114-G116 PolarHBondContact O-N 3.32Å; G116-R118 PolarHBondContact O-N 3.02Å
117	Q	65.6	Low	79.6	Confident	120 Å²	120	72.6 Å²	72.6	56%	0.561	38%	0.377	S	S	*	.			trans	-71.6	107.8	173.7	-69.7	-170.4	-30.2	0	0	110.1	D115	D115-Q117 PolarHBondContact O-N 3.27Å
118	R	67.4	Low	79.2	Confident	121 Å²	121	71.1 Å²	71.1	46%	0.457	37%	0.367	S	S	.	.			trans	-103.5	151	179.8	-63.4	174.6	-169.2	141.7	7.6	110.3	G116	G116-R118 PolarHBondContact O-N 3.02Å
119	L	72.6	Confident	78.6	Confident	53 Å²	53	79.4 Å²	79.4	28%	0.277	41%	0.411	S	S	.	.			trans	-68.1	151.3	167.9	-73.6	159.1	0	0	0	109.1	Y121 T122 Y246 L247	L119-Y121 HydrophobicContact CB-CD2 4.39Å; L119-Y121 PolarHBondContact O-N 3.05Å; L119-T122 PolarHBondContact N-OG1 3Å; L119-T122 PolarHBondContact O-N 3.24Å; L119-T122 PolarHBondContact O-OG1 2.75Å; L119-Y246 HydrophobicContact CD1-CG 4.38Å; L119-Y246 HydrophobicContact CD2-CD2 4.46Å; L119-Y246 HydrophobicContact CD2-CG 4.31Å; L119-Y246 HydrophobicContact CG-CG 4.14Å; L119-L247 HydrophobicContact CD1-CD2 4.3Å
120	I	78.1	Confident	78.8	Confident	162 Å²	162	80.3 Å²	80.3	83%	0.831	41%	0.414	S	S	*	.	T	Hydrogen-bonded Turn	trans	-53.5	-26.6	168.9	-70.4	167.5	0	0	0	111.1
121	Y	76	Confident	78.9	Confident	108 Å²	108	83.5 Å²	83.5	42%	0.424	44%	0.436	S	S	.	.	T	Hydrogen-bonded Turn	trans	-83.7	-6.9	-179	-51.9	-65.1	0	0	0	114.8	L119 P123 V148	L119-Y121 HydrophobicContact CB-CD2 4.39Å; L119-Y121 PolarHBondContact O-N 3.05Å; Y121-P123 VanDerWaalsContact C-CD 3.45Å; Y121-P123 WeakPolarHBondContact O-CD 3.19Å; Y121-V148 HydrophobicContact CD1-CG1 4.28Å; Y121-V148 HydrophobicContact CD1-CG2 3.98Å; Y121-V148 HydrophobicContact CE1-CG1 3.93Å; Y121-V148 HydrophobicContact CE1-CG2 4.17Å
122	T	83.9	Confident	79	Confident	1 Å²	1	86.1 Å²	86.1	1%	0.006	46%	0.461	C	S	.	.			trans	-124.8	68.8	179.1	51.5	0	0	0	0	111.4	L119 F124 N141 L247 T251	L119-T122 PolarHBondContact N-OG1 3Å; L119-T122 PolarHBondContact O-N 3.24Å; L119-T122 PolarHBondContact O-OG1 2.75Å; T122-F124 PolarHBondContact O-N 3.16Å; T122-N141 HydrophobicContact CG2-CB 4.26Å; T122-L247 HydrophobicContact CG2-CD2 4.14Å; T122-T251 HydrophobicContact CG2-CG2 4.34Å
123	P	84.2	Confident	79.2	Confident	69 Å²	69	88.2 Å²	88.2	45%	0.448	47%	0.467	S	S	.	.			trans	-70.6	-27.2	-172.4	28	-35.3	0	0	0	114	Y121 N141 I144	Y121-P123 VanDerWaalsContact C-CD 3.45Å; Y121-P123 WeakPolarHBondContact O-CD 3.19Å; P123-N141 WeakPolarHBondContact CD-OD1 3.33Å; P123-I144 HydrophobicContact CG-CD1 4.04Å
124	F	85.1	Confident	79.6	Confident	81 Å²	81	86.8 Å²	86.8	36%	0.355	46%	0.459	S	S	.	.	S	Bend	trans	-89.9	128.1	-173.2	-58.1	-72.3	0	0	0	112	T122 N137 L140 N141 I144	T122-F124 PolarHBondContact O-N 3.16Å; F124-N137 HydrophobicContact CB-CB 3.92Å; F124-L140 HydrophobicContact CD2-CB 3.84Å; F124-L140 HydrophobicContact CD2-CD1 4.42Å; F124-L140 HydrophobicContact CE2-CB 3.9Å; F124-L140 HydrophobicContact CE2-CD1 4.19Å; F124-L140 HydrophobicContact CZ-CD1 4.43Å; F124-N141 WeakPolarHBondContact CB-OD1 3.48Å; F124-N141 WeakPolarHBondContact CD2-OD1 3.41Å; F124-N141 PolarHBondContact N-OD1 3.22Å; F124-N141 PolarHBondContact O-ND2 3.06Å; F124-I144 HydrophobicContact CD2-CD1 4.48Å; F124-I144 HydrophobicContact CE2-CD1 3.93Å
125	P	82.1	Confident	80.4	Confident	47 Å²	47	82.8 Å²	82.8	31%	0.305	44%	0.441	S	S	.	.			trans	-70.7	142.3	176.2	27.9	-33.1	0	0	0	112.3	N137	P125-N137 PolarHBondContact O-ND2 3.26Å
126	E	79.1	Confident	81.7	Confident	22 Å²	22	82 Å²	82	10%	0.103	44%	0.439	C	S	.	.	S	Bend	trans	-92.2	-10.9	172.3	-70.1	-171.6	178.8	0	0	113.4	T128 R134 S138 P248 W250 T251	E126-T128 PolarHBondContact O-N 3.34Å; E126-R134 HydrophobicContact CB-CG 4.12Å; E126-R134 WeakPolarHBondContact O-CG 3.44Å; E126-R134 PolarHBondContact O-NE 3.29Å; E126-S138 WeakPolarHBondContact OE1-CB 3.24Å; E126-P248 HydrophobicContact CB-CB 4.5Å; E126-P248 HydrophobicContact CG-CB 3.92Å; E126-P248 WeakPolarHBondContact OE1-CB 3.36Å; E126-P248 WeakPolarHBondContact OE2-CB 3.41Å; E126-W250 PolarHBondContact OE2-N 3.45Å; E126-W250 VanDerWaalsContact OE2-N 3.14Å; E126-T251 VanDerWaalsContact OE1-CB 3.26Å; E126-T251 WeakPolarHBondContact OE1-CB 3.46Å; E126-T251 PolarHBondContact OE1-N 3.19Å; E126-T251 PolarHBondContact OE1-OG1 3.33Å
127	E	77.8	Confident	83.1	Confident	159 Å²	159	80.3 Å²	80.3	74%	0.743	42%	0.418	S	S	*	.			trans	-76.2	72.6	172.9	-67.1	176.5	-161.5	0	0	110.2
128	T	83.7	Confident	84.3	Confident	17 Å²	17	74.8 Å²	74.8	10%	0.104	39%	0.392	C	S	.	.			trans	-119.2	150.7	175.1	60.3	0	0	0	0	111	E126 T130 Q133 R134	E126-T128 PolarHBondContact O-N 3.34Å; T128-T130 VanDerWaalsContact C-N 3.27Å; T128-T130 PolarHBondContact O-N 3.05Å; T128-T130 PolarHBondContact OG1-O 2.88Å; T128-Q133 HydrophobicContact CG2-CG 4.07Å; T128-R134 PolarHBondContact O-NH2 2.9Å; T128-R134 WeakPolarHBondContact OG1-CA 3.3Å; T128-R134 WeakPolarHBondContact OG1-CB 3.3Å; T128-R134 PolarHBondContact OG1-N 3.38Å; T128-R134 VanDerWaalsContact OG1-N 3.11Å
129	D	80.8	Confident	85.5	Confident	175 Å²	175	73.2 Å²	73.2	94%	0.936	39%	0.392	S	S	*	.	S	Bend	trans	-66.1	-27.2	-176.8	-60.2	-36.2	0	0	0	113.3
130	T	91.8	Very high	86.5	Confident	70 Å²	70	74.1 Å²	74.1	43%	0.429	40%	0.397	S	S	.	.	S	Bend	trans	-108.1	137.8	-179.7	67.2	0	0	0	0	112.1	T128 A132 Q133 R134	T128-T130 VanDerWaalsContact C-N 3.27Å; T128-T130 PolarHBondContact O-N 3.05Å; T128-T130 PolarHBondContact OG1-O 2.88Å; T130-A132 VanDerWaalsContact C-N 3.29Å; T130-A132 PolarHBondContact O-N 3.03Å; T130-Q133 PolarHBondContact O-N 2.85Å; T130-Q133 WeakPolarHBondContact OG1-CB 3.45Å; T130-Q133 PolarHBondContact OG1-N 3.33Å; T130-R134 PolarHBondContact O-N 3.31Å
131	V	90.7	Very high	87.1	Confident	99 Å²	99	66.4 Å²	66.4	60%	0.6	36%	0.358	S	S	*	.	H	α-helix	trans	-62.7	-37.6	176.4	179	0	0	0	0	111.1	R134 A135	V131-R134 PolarHBondContact O-N 3.14Å; V131-A135 WeakPolarHBondContact O-CB 3.22Å; V131-A135 PolarHBondContact O-N 3Å
132	A	90.3	Very high	87.8	Confident	72 Å²	72	61.3 Å²	61.3	60%	0.595	34%	0.337	S	S	*	.	H	α-helix	trans	-61.9	-45.1	177.9	0	0	0	0	0	111.8	T130 A135 V136	T130-A132 VanDerWaalsContact C-N 3.29Å; T130-A132 PolarHBondContact O-N 3.03Å; A132-A135 PolarHBondContact O-N 3.33Å; A132-V136 WeakPolarHBondContact O-CG2 3.48Å; A132-V136 PolarHBondContact O-N 3.32Å
133	Q	90.3	Very high	88.2	Confident	102 Å²	102	64.7 Å²	64.7	48%	0.477	36%	0.358	S	S	.	.	H	α-helix	trans	-68	-37.8	177.4	-169.6	177.7	-7.3	0	0	111.7	T128 T130 A135 V136 N137	T128-Q133 HydrophobicContact CG2-CG 4.07Å; T130-Q133 PolarHBondContact O-N 2.85Å; T130-Q133 WeakPolarHBondContact OG1-CB 3.45Å; T130-Q133 PolarHBondContact OG1-N 3.33Å; Q133-A135 VanDerWaalsContact C-N 3.34Å; Q133-A135 PolarHBondContact O-N 3.45Å; Q133-V136 PolarHBondContact O-N 2.91Å; Q133-N137 WeakPolarHBondContact O-CB 3.33Å; Q133-N137 PolarHBondContact O-N 3Å; Q133-N137 PolarHBondContact O-OD1 2.93Å
134	R	90.5	Very high	88.6	Confident	82 Å²	82	64.4 Å²	64.4	31%	0.309	35%	0.352	S	S	.	.	H	α-helix	trans	-59	-45.8	173	-176.4	178.2	-59.6	164.2	8.1	111.5	E126 T128 T130 V131 N137 S138 W250	E126-R134 HydrophobicContact CB-CG 4.12Å; E126-R134 WeakPolarHBondContact O-CG 3.44Å; E126-R134 PolarHBondContact O-NE 3.29Å; T128-R134 PolarHBondContact O-NH2 2.9Å; T128-R134 WeakPolarHBondContact OG1-CA 3.3Å; T128-R134 WeakPolarHBondContact OG1-CB 3.3Å; T128-R134 PolarHBondContact OG1-N 3.38Å; T128-R134 VanDerWaalsContact OG1-N 3.11Å; T130-R134 PolarHBondContact O-N 3.31Å; V131-R134 PolarHBondContact O-N 3.14Å; R134-N137 PolarHBondContact O-N 3.4Å; R134-S138 WeakPolarHBondContact O-CB 3.33Å; R134-S138 PolarHBondContact O-N 3.49Å; R134-S138 PolarHBondContact O-OG 3.26Å; R134-W250 HydrophobicContact CG-CG 4.47Å
135	A	91.4	Very high	88.8	Confident	29 Å²	29	61.4 Å²	61.4	24%	0.24	34%	0.34	C	S	.	.	H	α-helix	trans	-64.7	-43.1	178.6	0	0	0	0	0	112	V131 A132 Q133 S138 I139	V131-A135 WeakPolarHBondContact O-CB 3.22Å; V131-A135 PolarHBondContact O-N 3Å; A132-A135 PolarHBondContact O-N 3.33Å; Q133-A135 VanDerWaalsContact C-N 3.34Å; Q133-A135 PolarHBondContact O-N 3.45Å; A135-S138 WeakPolarHBondContact CA-OG 3.32Å; A135-S138 PolarHBondContact O-N 2.86Å; A135-S138 PolarHBondContact O-OG 3.01Å; A135-I139 WeakPolarHBondContact O-CB 3.46Å; A135-I139 WeakPolarHBondContact O-CD1 3.35Å; A135-I139 WeakPolarHBondContact O-CG1 3.14Å; A135-I139 PolarHBondContact O-N 2.7Å
136	V	92.1	Very high	89.2	Confident	79 Å²	79	60.1 Å²	60.1	48%	0.479	33%	0.33	S	S	.	.	H	α-helix	trans	-63.8	-44.6	176.5	172.2	0	0	0	0	110.8	A132 Q133 S138 I139 L140	A132-V136 WeakPolarHBondContact O-CG2 3.48Å; A132-V136 PolarHBondContact O-N 3.32Å; Q133-V136 PolarHBondContact O-N 2.91Å; V136-S138 PolarHBondContact O-N 2.99Å; V136-I139 PolarHBondContact O-N 3.26Å; V136-L140 HydrophobicContact CG1-CD1 4.03Å; V136-L140 HydrophobicContact CG1-CG 4.44Å; V136-L140 VanDerWaalsContact O-CG 3.3Å; V136-L140 WeakPolarHBondContact O-CG 3.47Å; V136-L140 PolarHBondContact O-N 3.19Å
137	N	90.9	Very high	89.7	Confident	19 Å²	19	62.6 Å²	62.6	10%	0.102	35%	0.347	C	S	.	.	H	α-helix	trans	-62.8	-41.6	178.4	-71.8	-1.8	0	0	0	112	F124 P125 Q133 R134 L140 N141	F124-N137 HydrophobicContact CB-CB 3.92Å; P125-N137 PolarHBondContact O-ND2 3.26Å; Q133-N137 WeakPolarHBondContact O-CB 3.33Å; Q133-N137 PolarHBondContact O-N 3Å; Q133-N137 PolarHBondContact O-OD1 2.93Å; R134-N137 PolarHBondContact O-N 3.4Å; N137-L140 PolarHBondContact O-N 3.49Å; N137-N141 WeakPolarHBondContact O-CB 3.3Å; N137-N141 VanDerWaalsContact O-CG 3.3Å; N137-N141 PolarHBondContact O-N 3.48Å; N137-N141 PolarHBondContact O-ND2 2.94Å
138	S	91.5	Very high	90.4	Very high	3 Å²	3	57 Å²	57	2%	0.021	32%	0.323	C	S	.	.	H	α-helix	trans	-68.3	-39	177.9	68	0	0	0	0	112.3	E126 R134 A135 V136 N141 A142	E126-S138 WeakPolarHBondContact OE1-CB 3.24Å; R134-S138 WeakPolarHBondContact O-CB 3.33Å; R134-S138 PolarHBondContact O-N 3.49Å; R134-S138 PolarHBondContact O-OG 3.26Å; A135-S138 WeakPolarHBondContact CA-OG 3.32Å; A135-S138 PolarHBondContact O-N 2.86Å; A135-S138 PolarHBondContact O-OG 3.01Å; V136-S138 PolarHBondContact O-N 2.99Å; S138-N141 PolarHBondContact O-N 2.72Å; S138-A142 VanDerWaalsContact O-CB 3.29Å; S138-A142 WeakPolarHBondContact O-CB 3.29Å; S138-A142 PolarHBondContact O-N 3.27Å
139	I	93.6	Very high	90.6	Very high	88 Å²	88	58.8 Å²	58.8	45%	0.451	33%	0.332	S	S	.	.	H	α-helix	trans	-60.6	-45.9	172.3	-69.4	161.5	0	0	0	110.9	A135 V136 A142 T143 L254	A135-I139 WeakPolarHBondContact O-CB 3.46Å; A135-I139 WeakPolarHBondContact O-CD1 3.35Å; A135-I139 WeakPolarHBondContact O-CG1 3.14Å; A135-I139 PolarHBondContact O-N 2.7Å; V136-I139 PolarHBondContact O-N 3.26Å; I139-A142 PolarHBondContact O-N 3.37Å; I139-T143 WeakPolarHBondContact O-CB 3.31Å; I139-T143 PolarHBondContact O-N 3.49Å; I139-T143 PolarHBondContact O-OG1 3.01Å; I139-L254 HydrophobicContact CB-CD1 4.16Å; I139-L254 HydrophobicContact CG1-CD1 3.6Å
140	L	91.8	Very high	91	Very high	73 Å²	73	52.9 Å²	52.9	38%	0.382	30%	0.299	S	S	.	.	H	α-helix	trans	-63.4	-47.2	178.8	-71.7	172.7	0	0	0	111.6	F124 V136 N137 T143 I144	F124-L140 HydrophobicContact CD2-CB 3.84Å; F124-L140 HydrophobicContact CD2-CD1 4.42Å; F124-L140 HydrophobicContact CE2-CB 3.9Å; F124-L140 HydrophobicContact CE2-CD1 4.19Å; F124-L140 HydrophobicContact CZ-CD1 4.43Å; V136-L140 HydrophobicContact CG1-CD1 4.03Å; V136-L140 HydrophobicContact CG1-CG 4.44Å; V136-L140 VanDerWaalsContact O-CG 3.3Å; V136-L140 WeakPolarHBondContact O-CG 3.47Å; V136-L140 PolarHBondContact O-N 3.19Å; N137-L140 PolarHBondContact O-N 3.49Å; L140-T143 PolarHBondContact O-N 2.9Å; L140-I144 VanDerWaalsContact O-CG1 3.3Å; L140-I144 WeakPolarHBondContact O-CG1 3.26Å; L140-I144 PolarHBondContact O-N 3.2Å
141	N	91.5	Very high	90.9	Very high	0 Å²	0	53.1 Å²	53.1	0%	0	30%	0.301	C	S	.	.	H	α-helix	trans	-58.3	-49	175.6	-77	-24.6	0	0	0	112	T122 P123 F124 N137 S138 T143 I144 M145 T251	T122-N141 HydrophobicContact CG2-CB 4.26Å; P123-N141 WeakPolarHBondContact CD-OD1 3.33Å; F124-N141 WeakPolarHBondContact CB-OD1 3.48Å; F124-N141 WeakPolarHBondContact CD2-OD1 3.41Å; F124-N141 PolarHBondContact N-OD1 3.22Å; F124-N141 PolarHBondContact O-ND2 3.06Å; N137-N141 WeakPolarHBondContact O-CB 3.3Å; N137-N141 VanDerWaalsContact O-CG 3.3Å; N137-N141 PolarHBondContact O-N 3.48Å; N137-N141 PolarHBondContact O-ND2 2.94Å; S138-N141 PolarHBondContact O-N 2.72Å; N141-T143 VanDerWaalsContact C-N 3.32Å; N141-T143 PolarHBondContact O-N 2.87Å; N141-I144 PolarHBondContact O-N 3.06Å; N141-M145 WeakPolarHBondContact O-CB 3.45Å; N141-M145 PolarHBondContact O-N 3.22Å; N141-T251 HydrophobicContact CB-CG2 3.97Å
142	A	91.1	Very high	90.8	Very high	0 Å²	0	52.7 Å²	52.7	0%	0	29%	0.293	C	S	.	.	H	α-helix	trans	-60.5	-43.9	178.7	0	0	0	0	0	111.1	S138 I139 I144 M145 I146 T251 L254 I255	S138-A142 VanDerWaalsContact O-CB 3.29Å; S138-A142 WeakPolarHBondContact O-CB 3.29Å; S138-A142 PolarHBondContact O-N 3.27Å; I139-A142 PolarHBondContact O-N 3.37Å; A142-I144 PolarHBondContact O-N 3.42Å; A142-M145 PolarHBondContact O-N 3.36Å; A142-I146 HydrophobicContact CB-CD1 4.38Å; A142-I146 WeakPolarHBondContact O-CB 3.35Å; A142-I146 VanDerWaalsContact O-CD1 3.25Å; A142-I146 WeakPolarHBondContact O-CD1 3.3Å; A142-I146 WeakPolarHBondContact O-CG1 3.09Å; A142-I146 PolarHBondContact O-N 2.9Å; A142-T251 HydrophobicContact CB-CG2 4.41Å; A142-L254 HydrophobicContact CB-CB 4.17Å; A142-L254 HydrophobicContact CB-CD1 3.94Å; A142-L254 HydrophobicContact CB-CD2 3.82Å; A142-L254 HydrophobicContact CB-CG 4.2Å; A142-I255 HydrophobicContact CB-CG1 3.98Å
143	T	91.8	Very high	90.6	Very high	72 Å²	72	51.2 Å²	51.2	44%	0.442	28%	0.277	S	S	.	.	H	α-helix	trans	-60.7	-44.2	178.6	-57.8	0	0	0	0	111.8	I139 L140 N141 T147	I139-T143 WeakPolarHBondContact O-CB 3.31Å; I139-T143 PolarHBondContact O-N 3.49Å; I139-T143 PolarHBondContact O-OG1 3.01Å; L140-T143 PolarHBondContact O-N 2.9Å; N141-T143 VanDerWaalsContact C-N 3.32Å; N141-T143 PolarHBondContact O-N 2.87Å; T143-T147 WeakPolarHBondContact O-CB 3.39Å; T143-T147 PolarHBondContact O-N 2.86Å; T143-T147 PolarHBondContact O-OG1 3.2Å
144	I	92.1	Very high	90.4	Very high	64 Å²	64	50.5 Å²	50.5	33%	0.328	28%	0.276	S	S	.	.	H	α-helix	trans	-60.9	-49.4	176.3	-68.4	164.4	0	0	0	110.1	P123 F124 L140 N141 A142 I146 T147 V148	P123-I144 HydrophobicContact CG-CD1 4.04Å; F124-I144 HydrophobicContact CD2-CD1 4.48Å; F124-I144 HydrophobicContact CE2-CD1 3.93Å; L140-I144 VanDerWaalsContact O-CG1 3.3Å; L140-I144 WeakPolarHBondContact O-CG1 3.26Å; L140-I144 PolarHBondContact O-N 3.2Å; N141-I144 PolarHBondContact O-N 3.06Å; A142-I144 PolarHBondContact O-N 3.42Å; I144-I146 PolarHBondContact O-N 3.45Å; I144-T147 WeakPolarHBondContact O-CB 3.23Å; I144-T147 PolarHBondContact O-N 3.33Å; I144-V148 WeakPolarHBondContact O-CG2 3.16Å; I144-V148 PolarHBondContact O-N 2.99Å
145	M	90.3	Very high	90.4	Very high	17 Å²	17	49.7 Å²	49.7	8%	0.084	28%	0.28	C	S	.	.	H	α-helix	trans	-62.8	-44.8	-177.8	-168.5	-96	-167.4	0	0	112	N141 A142 T147 V148 I149 F243 L247 I255	N141-M145 WeakPolarHBondContact O-CB 3.45Å; N141-M145 PolarHBondContact O-N 3.22Å; A142-M145 PolarHBondContact O-N 3.36Å; M145-T147 PolarHBondContact O-N 3.02Å; M145-V148 PolarHBondContact O-N 3.29Å; M145-I149 HydrophobicContact CE-CD1 3.81Å; M145-I149 WeakPolarHBondContact O-CG1 3.47Å; M145-I149 PolarHBondContact O-N 3.2Å; M145-I149 HydrophobicContact SD-CD1 3.46Å; M145-I149 WeakPolarHBondContact SD-CD1 3.3Å; M145-I149 HydrophobicContact SD-CG1 4.33Å; M145-F243 HydrophobicContact CE-CE1 4.08Å; M145-F243 HydrophobicContact CE-CZ 4.35Å; M145-L247 HydrophobicContact CE-CD1 4.4Å; M145-L247 HydrophobicContact CE-CD2 4.5Å; M145-I255 HydrophobicContact CB-CD1 4.33Å; M145-I255 HydrophobicContact CE-CD1 4.11Å; M145-I255 HydrophobicContact CE-CG2 4.43Å; M145-I255 HydrophobicContact CG-CD1 4.09Å; M145-I255 HydrophobicContact SD-CD1 3.55Å; M145-I255 VanDerWaalsContact SD-CD1 3.55Å; M145-I255 HydrophobicContact SD-CG1 4.01Å; M145-I255 HydrophobicContact SD-CG2 4.07Å
146	I	90.1	Very high	90	Very high	21 Å²	21	49.5 Å²	49.5	11%	0.108	28%	0.275	C	S	.	.	H	α-helix	trans	-62.9	-42.4	175.6	-68.6	157.2	0	0	0	111	A142 I144 V148 I149 I150 V258	A142-I146 HydrophobicContact CB-CD1 4.38Å; A142-I146 WeakPolarHBondContact O-CB 3.35Å; A142-I146 VanDerWaalsContact O-CD1 3.25Å; A142-I146 WeakPolarHBondContact O-CD1 3.3Å; A142-I146 WeakPolarHBondContact O-CG1 3.09Å; A142-I146 PolarHBondContact O-N 2.9Å; I144-I146 PolarHBondContact O-N 3.45Å; I146-V148 VanDerWaalsContact C-N 3.3Å; I146-V148 PolarHBondContact O-N 2.92Å; I146-I149 PolarHBondContact O-N 3.36Å; I146-I150 HydrophobicContact CG2-CD1 3.7Å; I146-I150 HydrophobicContact CG2-CG1 4.27Å; I146-I150 VanDerWaalsContact O-CG1 3.3Å; I146-I150 WeakPolarHBondContact O-CG1 3.5Å; I146-I150 PolarHBondContact O-N 3.46Å; I146-V258 HydrophobicContact CD1-CB 3.59Å; I146-V258 HydrophobicContact CD1-CG1 3.48Å; I146-V258 VanDerWaalsContact CD1-CG1 3.48Å; I146-V258 HydrophobicContact CD1-CG2 4.21Å; I146-V258 HydrophobicContact CG1-CG1 4.43Å
147	T	90.7	Very high	89.6	Confident	73 Å²	73	46.9 Å²	46.9	45%	0.448	26%	0.259	S	S	.	.	H	α-helix	trans	-59.6	-43.3	177.1	-58.7	0	0	0	0	110.8	T143 I144 M145 I150 V151	T143-T147 WeakPolarHBondContact O-CB 3.39Å; T143-T147 PolarHBondContact O-N 2.86Å; T143-T147 PolarHBondContact O-OG1 3.2Å; I144-T147 WeakPolarHBondContact O-CB 3.23Å; I144-T147 PolarHBondContact O-N 3.33Å; M145-T147 PolarHBondContact O-N 3.02Å; T147-I150 PolarHBondContact O-N 3.42Å; T147-V151 HydrophobicContact CG2-CG2 4.39Å; T147-V151 WeakPolarHBondContact O-CB 3.44Å; T147-V151 VanDerWaalsContact O-CG2 3.26Å; T147-V151 WeakPolarHBondContact O-CG2 3.36Å; T147-V151 PolarHBondContact O-N 3.44Å
148	V	91.3	Very high	89.4	Confident	41 Å²	41	50.3 Å²	50.3	25%	0.248	28%	0.277	C	S	.	.	H	α-helix	trans	-62.8	-44.6	175.9	172.6	0	0	0	0	111.3	Y121 I144 M145 I146 I150 V151 M152	Y121-V148 HydrophobicContact CD1-CG1 4.28Å; Y121-V148 HydrophobicContact CD1-CG2 3.98Å; Y121-V148 HydrophobicContact CE1-CG1 3.93Å; Y121-V148 HydrophobicContact CE1-CG2 4.17Å; I144-V148 WeakPolarHBondContact O-CG2 3.16Å; I144-V148 PolarHBondContact O-N 2.99Å; M145-V148 PolarHBondContact O-N 3.29Å; I146-V148 VanDerWaalsContact C-N 3.3Å; I146-V148 PolarHBondContact O-N 2.92Å; V148-I150 PolarHBondContact O-N 2.94Å; V148-V151 PolarHBondContact O-N 3.43Å; V148-M152 HydrophobicContact CG1-CG 4.29Å; V148-M152 WeakPolarHBondContact O-CB 3.11Å; V148-M152 VanDerWaalsContact O-CG 3.24Å; V148-M152 WeakPolarHBondContact O-CG 3.29Å; V148-M152 PolarHBondContact O-N 3.42Å
149	I	88.4	Confident	89.1	Confident	56 Å²	56	51.7 Å²	51.7	29%	0.287	28%	0.284	S	S	.	.	H	α-helix	trans	-57.9	-50.1	175.8	-69.2	172.6	0	0	0	110.2	M145 I146 V151 M152 T153 I259	M145-I149 HydrophobicContact CE-CD1 3.81Å; M145-I149 WeakPolarHBondContact O-CG1 3.47Å; M145-I149 PolarHBondContact O-N 3.2Å; M145-I149 HydrophobicContact SD-CD1 3.46Å; M145-I149 WeakPolarHBondContact SD-CD1 3.3Å; M145-I149 HydrophobicContact SD-CG1 4.33Å; I146-I149 PolarHBondContact O-N 3.36Å; I149-V151 PolarHBondContact O-N 3.37Å; I149-M152 PolarHBondContact O-N 2.96Å; I149-T153 HydrophobicContact CG2-CG2 4.28Å; I149-T153 WeakPolarHBondContact O-CG2 3.47Å; I149-T153 PolarHBondContact O-N 3.02Å; I149-I259 HydrophobicContact CD1-CD1 3.96Å
150	I	87.9	Confident	88.6	Confident	50 Å²	50	48.2 Å²	48.2	26%	0.256	27%	0.265	S	S	.	.	H	α-helix	trans	-59.4	-49.3	179.8	-67	170.1	0	0	0	110.3	I146 T147 V148 M152 T153 L154 Y262	I146-I150 HydrophobicContact CG2-CD1 3.7Å; I146-I150 HydrophobicContact CG2-CG1 4.27Å; I146-I150 VanDerWaalsContact O-CG1 3.3Å; I146-I150 WeakPolarHBondContact O-CG1 3.5Å; I146-I150 PolarHBondContact O-N 3.46Å; T147-I150 PolarHBondContact O-N 3.42Å; V148-I150 PolarHBondContact O-N 2.94Å; I150-M152 VanDerWaalsContact C-N 3.33Å; I150-M152 PolarHBondContact O-N 2.97Å; I150-T153 PolarHBondContact O-N 3.41Å; I150-T153 VanDerWaalsContact O-N 3.14Å; I150-T153 PolarHBondContact O-OG1 3.24Å; I150-L154 HydrophobicContact CG2-CD1 4.07Å; I150-L154 HydrophobicContact CG2-CG 4.37Å; I150-L154 WeakPolarHBondContact O-CG 3.05Å; I150-L154 PolarHBondContact O-N 2.89Å; I150-Y262 HydrophobicContact CD1-CD2 4.11Å; I150-Y262 HydrophobicContact CD1-CE2 3.82Å; I150-Y262 HydrophobicContact CG1-CD2 4.33Å; I150-Y262 HydrophobicContact CG1-CE2 3.74Å
151	V	91.1	Very high	88.1	Confident	75 Å²	75	52.9 Å²	52.9	46%	0.455	28%	0.282	S	S	.	.	H	α-helix	trans	-58.7	-44.9	178.2	170.4	0	0	0	0	111	T147 V148 I149 T153 L154 V155	T147-V151 HydrophobicContact CG2-CG2 4.39Å; T147-V151 WeakPolarHBondContact O-CB 3.44Å; T147-V151 VanDerWaalsContact O-CG2 3.26Å; T147-V151 WeakPolarHBondContact O-CG2 3.36Å; T147-V151 PolarHBondContact O-N 3.44Å; V148-V151 PolarHBondContact O-N 3.43Å; I149-V151 PolarHBondContact O-N 3.37Å; V151-T153 VanDerWaalsContact C-N 3.35Å; V151-T153 PolarHBondContact O-N 3.29Å; V151-L154 PolarHBondContact O-N 2.99Å; V151-V155 HydrophobicContact CG1-CG2 4.42Å; V151-V155 VanDerWaalsContact O-CG2 3.32Å; V151-V155 WeakPolarHBondContact O-CG2 3.46Å; V151-V155 PolarHBondContact O-N 3.38Å
152	M	87.6	Confident	87.8	Confident	90 Å²	90	60.7 Å²	60.7	44%	0.443	31%	0.313	S	S	.	.	H	α-helix	trans	-63	-39.7	176.7	-70.7	-65	173.3	0	0	112.2	V148 I149 I150 V155 L156	V148-M152 HydrophobicContact CG1-CG 4.29Å; V148-M152 WeakPolarHBondContact O-CB 3.11Å; V148-M152 VanDerWaalsContact O-CG 3.24Å; V148-M152 WeakPolarHBondContact O-CG 3.29Å; V148-M152 PolarHBondContact O-N 3.42Å; I149-M152 PolarHBondContact O-N 2.96Å; I150-M152 VanDerWaalsContact C-N 3.33Å; I150-M152 PolarHBondContact O-N 2.97Å; M152-V155 PolarHBondContact O-N 3.03Å; M152-L156 PolarHBondContact O-N 3.46Å
153	T	86.9	Confident	87.4	Confident	41 Å²	41	68 Å²	68	25%	0.252	34%	0.341	S	S	.	.	H	α-helix	trans	-64.5	-39.6	174.6	67.1	0	0	0	0	112	I149 I150 V151 L156 V157	I149-T153 HydrophobicContact CG2-CG2 4.28Å; I149-T153 WeakPolarHBondContact O-CG2 3.47Å; I149-T153 PolarHBondContact O-N 3.02Å; I150-T153 PolarHBondContact O-N 3.41Å; I150-T153 VanDerWaalsContact O-N 3.14Å; I150-T153 PolarHBondContact O-OG1 3.24Å; V151-T153 VanDerWaalsContact C-N 3.35Å; V151-T153 PolarHBondContact O-N 3.29Å; T153-L156 PolarHBondContact O-N 3.41Å; T153-V157 VanDerWaalsContact O-CG2 3.28Å; T153-V157 WeakPolarHBondContact O-CG2 3.44Å; T153-V157 PolarHBondContact O-N 2.91Å
154	L	86.6	Confident	87	Confident	88 Å²	88	66.7 Å²	66.7	46%	0.461	33%	0.334	S	S	.	.	H	α-helix	trans	-67	-40.4	176.1	-68.8	175.7	0	0	0	111.8	I150 V151 L156 V157 L158 P273	I150-L154 HydrophobicContact CG2-CD1 4.07Å; I150-L154 HydrophobicContact CG2-CG 4.37Å; I150-L154 WeakPolarHBondContact O-CG 3.05Å; I150-L154 PolarHBondContact O-N 2.89Å; V151-L154 PolarHBondContact O-N 2.99Å; L154-L156 VanDerWaalsContact C-N 3.33Å; L154-V157 PolarHBondContact O-N 2.84Å; L154-L158 WeakPolarHBondContact O-CB 3.19Å; L154-L158 PolarHBondContact O-N 2.79Å; L154-P273 HydrophobicContact CD2-CB 4.04Å; L154-P273 HydrophobicContact CD2-CG 4.44Å
155	V	89.4	Confident	86.5	Confident	65 Å²	65	67 Å²	67	39%	0.394	33%	0.331	S	S	.	.	H	α-helix	trans	-61.3	-43.1	174.3	169.6	0	0	0	0	110.6	V151 M152 L158 L159	V151-V155 HydrophobicContact CG1-CG2 4.42Å; V151-V155 VanDerWaalsContact O-CG2 3.32Å; V151-V155 WeakPolarHBondContact O-CG2 3.46Å; V151-V155 PolarHBondContact O-N 3.38Å; M152-V155 PolarHBondContact O-N 3.03Å; V155-L158 PolarHBondContact O-N 3.01Å; V155-L159 HydrophobicContact CG1-CD1 4.01Å; V155-L159 HydrophobicContact CG1-CG 4.41Å; V155-L159 WeakPolarHBondContact O-CB 3.35Å; V155-L159 VanDerWaalsContact O-CG 3.3Å; V155-L159 WeakPolarHBondContact O-CG 3.32Å; V155-L159 PolarHBondContact O-N 2.93Å
156	L	84.2	Confident	86.4	Confident	25 Å²	25	75.1 Å²	75.1	13%	0.131	37%	0.366	C	S	.	.	H	α-helix	trans	-60.5	-50.3	175.6	-167.8	158.2	0	0	0	111.2	M152 T153 L154 L158 L159 Y160 W171 L277	M152-L156 PolarHBondContact O-N 3.46Å; T153-L156 PolarHBondContact O-N 3.41Å; L154-L156 VanDerWaalsContact C-N 3.33Å; L156-L158 VanDerWaalsContact C-N 3.28Å; L156-L158 PolarHBondContact O-N 3.39Å; L156-L159 PolarHBondContact O-N 3.43Å; L156-Y160 WeakPolarHBondContact O-CB 3.25Å; L156-Y160 PolarHBondContact O-N 3.42Å; L156-W171 HydrophobicContact CB-CH2 4.27Å; L156-W171 HydrophobicContact CB-CZ3 3.79Å; L156-W171 HydrophobicContact CD1-CH2 4.15Å; L156-W171 HydrophobicContact CD1-CZ3 3.67Å; L156-W171 HydrophobicContact CG-CZ3 3.81Å; L156-L277 HydrophobicContact CD2-CD1 3.51Å
157	V	82.8	Confident	86.3	Confident	24 Å²	24	77.9 Å²	77.9	15%	0.145	38%	0.384	C	S	.	.	H	α-helix	trans	-61.1	-39.2	178.2	172.1	0	0	0	0	111.2	T153 L154 Y160 K161 P273 L277	T153-V157 VanDerWaalsContact O-CG2 3.28Å; T153-V157 WeakPolarHBondContact O-CG2 3.44Å; T153-V157 PolarHBondContact O-N 2.91Å; L154-V157 PolarHBondContact O-N 2.84Å; V157-Y160 WeakPolarHBondContact O-CB 3.2Å; V157-Y160 PolarHBondContact O-N 2.91Å; V157-K161 WeakPolarHBondContact O-CB 3.38Å; V157-K161 PolarHBondContact O-N 2.95Å; V157-P273 HydrophobicContact CG2-CB 4.17Å; V157-L277 HydrophobicContact CG2-CB 4.34Å; V157-L277 HydrophobicContact CG2-CD1 3.89Å
158	L	86.3	Confident	86	Confident	90 Å²	90	74.4 Å²	74.4	47%	0.471	36%	0.362	S	S	.	.	H	α-helix	trans	-65.7	-48.6	177.6	-176.4	143.9	0	0	0	111.1	L154 V155 L156 Y160 K161 Y162	L154-L158 WeakPolarHBondContact O-CB 3.19Å; L154-L158 PolarHBondContact O-N 2.79Å; V155-L158 PolarHBondContact O-N 3.01Å; L156-L158 VanDerWaalsContact C-N 3.28Å; L156-L158 PolarHBondContact O-N 3.39Å; L158-Y160 PolarHBondContact O-N 3.36Å; L158-K161 PolarHBondContact O-N 3.46Å; L158-K161 VanDerWaalsContact O-N 3.14Å; L158-Y162 HydrophobicContact CD1-CE2 3.99Å; L158-Y162 HydrophobicContact CD2-CD2 3.42Å; L158-Y162 VanDerWaalsContact CD2-CD2 3.42Å; L158-Y162 HydrophobicContact CD2-CE2 3.51Å; L158-Y162 HydrophobicContact CG-CD2 3.64Å; L158-Y162 HydrophobicContact CG-CE2 3.47Å; L158-Y162 VanDerWaalsContact CG-CE2 3.47Å; L158-Y162 WeakPolarHBondContact O-CD2 3.15Å; L158-Y162 PolarHBondContact O-N 2.89Å
159	L	86.2	Confident	85.6	Confident	32 Å²	32	78.7 Å²	78.7	17%	0.168	38%	0.38	C	S	.	.	H	α-helix	trans	-58.6	-38.2	174.9	-74.5	171.5	0	0	0	111.7	V155 L156 Y162 R163 C164 V167 I168	V155-L159 HydrophobicContact CG1-CD1 4.01Å; V155-L159 HydrophobicContact CG1-CG 4.41Å; V155-L159 WeakPolarHBondContact O-CB 3.35Å; V155-L159 VanDerWaalsContact O-CG 3.3Å; V155-L159 WeakPolarHBondContact O-CG 3.32Å; V155-L159 PolarHBondContact O-N 2.93Å; L156-L159 PolarHBondContact O-N 3.43Å; L159-Y162 PolarHBondContact O-N 2.94Å; L159-R163 PolarHBondContact O-N 3.46Å; L159-C164 HydrophobicContact CB-CB 4.39Å; L159-C164 HydrophobicContact CD2-CB 3.85Å; L159-C164 PolarHBondContact O-N 2.73Å; L159-V167 HydrophobicContact CD1-CG1 4Å; L159-V167 HydrophobicContact CD2-CB 4.48Å; L159-V167 HydrophobicContact CD2-CG1 4.13Å; L159-I168 HydrophobicContact CB-CD1 4.17Å; L159-I168 HydrophobicContact CB-CG1 3.91Å
160	Y	81.5	Confident	85.6	Confident	15 Å²	15	77.8 Å²	77.8	6%	0.059	38%	0.384	C	S	.	.	H	α-helix	trans	-64.1	-46.7	175.3	-172.7	-105	0	0	0	111.1	L156 V157 L158 Y162 R163 Y165 I168 T280 F289	L156-Y160 WeakPolarHBondContact O-CB 3.25Å; L156-Y160 PolarHBondContact O-N 3.42Å; V157-Y160 WeakPolarHBondContact O-CB 3.2Å; V157-Y160 PolarHBondContact O-N 2.91Å; L158-Y160 PolarHBondContact O-N 3.36Å; Y160-Y162 VanDerWaalsContact C-N 3.34Å; Y160-Y162 PolarHBondContact O-N 3.46Å; Y160-R163 PolarHBondContact O-N 3.25Å; Y160-Y165 HydrophobicContact CD2-CE1 4.37Å; Y160-Y165 HydrophobicContact CE2-CE1 4.02Å; Y160-I168 HydrophobicContact CD2-CD1 4.1Å; Y160-T280 HydrophobicContact CD1-CG2 4.39Å; Y160-T280 HydrophobicContact CE1-CG2 3.68Å; Y160-F289 HydrophobicContact CD2-CE2 4.02Å; Y160-F289 HydrophobicContact CD2-CZ 4.01Å; Y160-F289 HydrophobicContact CE2-CE2 4.18Å; Y160-F289 HydrophobicContact CE2-CZ 4.18Å
161	K	82.4	Confident	85.6	Confident	172 Å²	172	79.8 Å²	79.8	75%	0.748	39%	0.388	S	S	*	.	H	α-helix	trans	-61.7	-38.2	176.6	-172.9	173.6	-179	172.5	0	113	V157 L158 R163	V157-K161 WeakPolarHBondContact O-CB 3.38Å; V157-K161 PolarHBondContact O-N 2.95Å; L158-K161 PolarHBondContact O-N 3.46Å; L158-K161 VanDerWaalsContact O-N 3.14Å; K161-R163 PolarHBondContact O-N 3.08Å
162	Y	85.9	Confident	85.4	Confident	164 Å²	164	77.1 Å²	77.1	64%	0.643	37%	0.372	S	S	*	.	T	Hydrogen-bonded Turn	trans	-80	7.3	176.6	-73.7	-69.3	0	0	0	113.9	L158 L159 Y160 C164	L158-Y162 HydrophobicContact CD1-CE2 3.99Å; L158-Y162 HydrophobicContact CD2-CD2 3.42Å; L158-Y162 VanDerWaalsContact CD2-CD2 3.42Å; L158-Y162 HydrophobicContact CD2-CE2 3.51Å; L158-Y162 HydrophobicContact CG-CD2 3.64Å; L158-Y162 HydrophobicContact CG-CE2 3.47Å; L158-Y162 VanDerWaalsContact CG-CE2 3.47Å; L158-Y162 WeakPolarHBondContact O-CD2 3.15Å; L158-Y162 PolarHBondContact O-N 2.89Å; L159-Y162 PolarHBondContact O-N 2.94Å; Y160-Y162 VanDerWaalsContact C-N 3.34Å; Y160-Y162 PolarHBondContact O-N 3.46Å; Y162-C164 PolarHBondContact O-N 3.44Å
163	R	82.1	Confident	85.5	Confident	154 Å²	154	77.4 Å²	77.4	58%	0.581	37%	0.371	S	S	*	.	T	Hydrogen-bonded Turn	trans	56.1	31	-179.4	-63.7	-173.7	170.2	-172.7	-3.8	113.4	L159 Y160 K161 Y165	L159-R163 PolarHBondContact O-N 3.46Å; Y160-R163 PolarHBondContact O-N 3.25Å; K161-R163 PolarHBondContact O-N 3.08Å; R163-Y165 HydrophobicContact CB-CD2 4.11Å; R163-Y165 HydrophobicContact CB-CE2 3.66Å; R163-Y165 HydrophobicContact CG-CE2 3.9Å; R163-Y165 VanDerWaalsContact O-CD2 3.29Å; R163-Y165 WeakPolarHBondContact O-CD2 3.42Å; R163-Y165 PolarHBondContact O-N 2.96Å
164	C	83.6	Confident	85.7	Confident	44 Å²	44	80.6 Å²	80.6	30%	0.297	39%	0.385	S	S	.	.			trans	-79.1	50.7	177	-61.7	0	0	0	0	111.7	L159 Y162 K166 V167 I168	L159-C164 HydrophobicContact CB-CB 4.39Å; L159-C164 HydrophobicContact CD2-CB 3.85Å; L159-C164 PolarHBondContact O-N 2.73Å; Y162-C164 PolarHBondContact O-N 3.44Å; C164-K166 VanDerWaalsContact C-N 3.28Å; C164-K166 PolarHBondContact O-N 3.25Å; C164-V167 HydrophobicContact CB-CB 4.14Å; C164-V167 HydrophobicContact CB-CG2 4.12Å; C164-V167 WeakPolarHBondContact O-CA 3.31Å; C164-V167 WeakPolarHBondContact O-CB 3.4Å; C164-V167 PolarHBondContact O-N 3.26Å; C164-I168 PolarHBondContact O-N 2.84Å; C164-I168 VanDerWaalsContact O-N 3.09Å
165	Y	81.8	Confident	85.8	Confident	70 Å²	70	79.2 Å²	79.2	28%	0.275	38%	0.383	S	S	.	.	H	α-helix	trans	-57.1	-38	-172.6	-63.3	-74.9	0	0	0	113.4	Y160 R163 V167 I168 Q169 E286	Y160-Y165 HydrophobicContact CD2-CE1 4.37Å; Y160-Y165 HydrophobicContact CE2-CE1 4.02Å; R163-Y165 HydrophobicContact CB-CD2 4.11Å; R163-Y165 HydrophobicContact CB-CE2 3.66Å; R163-Y165 HydrophobicContact CG-CE2 3.9Å; R163-Y165 VanDerWaalsContact O-CD2 3.29Å; R163-Y165 WeakPolarHBondContact O-CD2 3.42Å; R163-Y165 PolarHBondContact O-N 2.96Å; Y165-V167 VanDerWaalsContact C-N 3.28Å; Y165-V167 PolarHBondContact O-N 2.78Å; Y165-I168 PolarHBondContact O-N 3.29Å; Y165-Q169 VanDerWaalsContact O-CB 3.3Å; Y165-Q169 WeakPolarHBondContact O-CB 3.32Å; Y165-Q169 PolarHBondContact O-N 2.95Å; Y165-E286 VanDerWaalsContact CE1-OE2 3.31Å; Y165-E286 WeakPolarHBondContact CE1-OE2 3.29Å; Y165-E286 PolarHBondContact OH-OE1 2.9Å; Y165-E286 PolarHBondContact OH-OE2 2.85Å
166	K	86.5	Confident	85.8	Confident	187 Å²	187	76.6 Å²	76.6	81%	0.813	37%	0.368	S	S	*	.	H	α-helix	trans	-62.1	-36	175.8	-67.9	-164	178.5	-179.6	0	112.7	C164 G170	C164-K166 VanDerWaalsContact C-N 3.28Å; C164-K166 PolarHBondContact O-N 3.25Å; K166-G170 PolarHBondContact O-N 3.21Å
167	V	88.4	Confident	86.2	Confident	80 Å²	80	78.3 Å²	78.3	49%	0.485	38%	0.377	S	S	.	.	H	α-helix	trans	-70.9	-44.4	177.1	-179.4	0	0	0	0	109.9	L159 C164 Y165 G170 W171	L159-V167 HydrophobicContact CD1-CG1 4Å; L159-V167 HydrophobicContact CD2-CB 4.48Å; L159-V167 HydrophobicContact CD2-CG1 4.13Å; C164-V167 HydrophobicContact CB-CB 4.14Å; C164-V167 HydrophobicContact CB-CG2 4.12Å; C164-V167 WeakPolarHBondContact O-CA 3.31Å; C164-V167 WeakPolarHBondContact O-CB 3.4Å; C164-V167 PolarHBondContact O-N 3.26Å; Y165-V167 VanDerWaalsContact C-N 3.28Å; Y165-V167 PolarHBondContact O-N 2.78Å; V167-G170 PolarHBondContact O-N 3.45Å; V167-W171 WeakPolarHBondContact O-CB 3.37Å; V167-W171 PolarHBondContact O-N 3.17Å
168	I	85.4	Confident	86.7	Confident	0 Å²	0	81.9 Å²	81.9	0%	0	39%	0.394	C	S	.	.	H	α-helix	trans	-63.5	-48	178.7	-57.7	170	0	0	0	110.5	L159 Y160 C164 Y165 G170 W171 L172 F289	L159-I168 HydrophobicContact CB-CD1 4.17Å; L159-I168 HydrophobicContact CB-CG1 3.91Å; Y160-I168 HydrophobicContact CD2-CD1 4.1Å; C164-I168 PolarHBondContact O-N 2.84Å; C164-I168 VanDerWaalsContact O-N 3.09Å; Y165-I168 PolarHBondContact O-N 3.29Å; I168-G170 PolarHBondContact O-N 3.1Å; I168-W171 PolarHBondContact O-N 3.44Å; I168-L172 HydrophobicContact CG2-CD1 3.97Å; I168-L172 HydrophobicContact CG2-CG 4.27Å; I168-L172 WeakPolarHBondContact O-CB 3.39Å; I168-L172 WeakPolarHBondContact O-CG 3.33Å; I168-L172 PolarHBondContact O-N 3.02Å; I168-F289 HydrophobicContact CB-CE1 4.37Å; I168-F289 HydrophobicContact CB-CZ 4.33Å; I168-F289 HydrophobicContact CD1-CZ 4.16Å; I168-F289 HydrophobicContact CG2-CD1 4.23Å; I168-F289 HydrophobicContact CG2-CE1 3.54Å; I168-F289 HydrophobicContact CG2-CE2 4.11Å; I168-F289 HydrophobicContact CG2-CZ 3.49Å; I168-F289 VanDerWaalsContact CG2-CZ 3.49Å
169	Q	82.9	Confident	86.9	Confident	130 Å²	130	78.3 Å²	78.3	61%	0.607	38%	0.376	S	S	*	.	H	α-helix	trans	-62	-45.3	178.4	-174.5	178.8	-5.4	0	0	111.4	Y165 F173	Y165-Q169 VanDerWaalsContact O-CB 3.3Å; Y165-Q169 WeakPolarHBondContact O-CB 3.32Å; Y165-Q169 PolarHBondContact O-N 2.95Å; Q169-F173 WeakPolarHBondContact O-CB 3.4Å; Q169-F173 PolarHBondContact O-N 3.48Å
170	G	88.2	Confident	87.2	Confident	37 Å²	37	76.8 Å²	76.8	38%	0.381	37%	0.368	S	S	.	.	H	α-helix	trans	-64.2	-40	177	0	0	0	0	0	112.8	K166 V167 I168 L174	K166-G170 PolarHBondContact O-N 3.21Å; V167-G170 PolarHBondContact O-N 3.45Å; I168-G170 PolarHBondContact O-N 3.1Å; G170-L174 VanDerWaalsContact O-CB 3.29Å; G170-L174 WeakPolarHBondContact O-CB 3.35Å; G170-L174 PolarHBondContact O-N 3.36Å
171	W	88.6	Confident	87.8	Confident	92 Å²	92	78.2 Å²	78.2	35%	0.348	37%	0.374	S	S	.	.	H	α-helix	trans	-68.9	-46.6	178.2	177.7	39	0	0	0	112.3	L156 V167 I168 L174 S175	L156-W171 HydrophobicContact CB-CH2 4.27Å; L156-W171 HydrophobicContact CB-CZ3 3.79Å; L156-W171 HydrophobicContact CD1-CH2 4.15Å; L156-W171 HydrophobicContact CD1-CZ3 3.67Å; L156-W171 HydrophobicContact CG-CZ3 3.81Å; V167-W171 WeakPolarHBondContact O-CB 3.37Å; V167-W171 PolarHBondContact O-N 3.17Å; I168-W171 PolarHBondContact O-N 3.44Å; W171-L174 PolarHBondContact O-N 2.77Å; W171-S175 WeakPolarHBondContact O-CB 3.5Å; W171-S175 PolarHBondContact O-N 3.24Å
172	L	85.3	Confident	88.4	Confident	20 Å²	20	75.1 Å²	75.1	11%	0.105	36%	0.361	C	S	.	.	H	α-helix	trans	-62.8	-42.5	175.5	-71.1	-178.7	0	0	0	111.4	I168 S175 S176 F289 L292	I168-L172 HydrophobicContact CG2-CD1 3.97Å; I168-L172 HydrophobicContact CG2-CG 4.27Å; I168-L172 WeakPolarHBondContact O-CB 3.39Å; I168-L172 WeakPolarHBondContact O-CG 3.33Å; I168-L172 PolarHBondContact O-N 3.02Å; L172-S175 PolarHBondContact O-N 2.84Å; L172-S176 PolarHBondContact O-N 3.36Å; L172-S176 PolarHBondContact O-OG 3Å; L172-S176 VanDerWaalsContact O-OG 3.14Å; L172-F289 HydrophobicContact CD1-CB 3.84Å; L172-F289 HydrophobicContact CD1-CD1 3.71Å; L172-F289 HydrophobicContact CD1-CD2 4.44Å; L172-F289 HydrophobicContact CD1-CE1 4.42Å; L172-F289 HydrophobicContact CD1-CG 3.73Å; L172-L292 HydrophobicContact CD1-CD1 4.13Å; L172-L292 HydrophobicContact CD2-CD1 4.13Å; L172-L292 HydrophobicContact CD2-CD2 4.48Å; L172-L292 HydrophobicContact CD2-CG 4.32Å
173	F	89.5	Confident	88.7	Confident	95 Å²	95	69.1 Å²	69.1	42%	0.417	34%	0.339	S	S	.	.	H	α-helix	trans	-60.7	-45	175.2	179.7	-87.6	0	0	0	112	Q169 S176 L177 M216	Q169-F173 WeakPolarHBondContact O-CB 3.4Å; Q169-F173 PolarHBondContact O-N 3.48Å; F173-S176 PolarHBondContact O-OG 3.11Å; F173-L177 HydrophobicContact CE1-CD1 3.78Å; F173-L177 HydrophobicContact CZ-CD1 4.27Å; F173-L177 WeakPolarHBondContact O-CB 3.48Å; F173-L177 PolarHBondContact O-N 3.37Å; F173-M216 HydrophobicContact CD1-CE 4.23Å; F173-M216 HydrophobicContact CD2-CE 3.25Å; F173-M216 HydrophobicContact CE1-CE 4.18Å; F173-M216 HydrophobicContact CE2-CE 3.2Å; F173-M216 HydrophobicContact CG-CE 3.8Å; F173-M216 HydrophobicContact CZ-CE 3.69Å
174	L	91.2	Very high	89.3	Confident	108 Å²	108	62 Å²	62	57%	0.565	31%	0.312	S	S	*	.	H	α-helix	trans	-66.1	-41.2	177.5	-177.7	64.8	0	0	0	111.4	G170 W171 L177 L178	G170-L174 VanDerWaalsContact O-CB 3.29Å; G170-L174 WeakPolarHBondContact O-CB 3.35Å; G170-L174 PolarHBondContact O-N 3.36Å; W171-L174 PolarHBondContact O-N 2.77Å; L174-L177 PolarHBondContact O-N 2.91Å; L174-L178 WeakPolarHBondContact O-CB 3.12Å; L174-L178 PolarHBondContact O-N 3.5Å
175	S	89.6	Confident	89.9	Confident	59 Å²	59	63 Å²	63	41%	0.413	31%	0.312	S	S	.	.	H	α-helix	trans	-62.3	-46.5	177.7	-172.4	0	0	0	0	111.4	W171 L172 L179	W171-S175 WeakPolarHBondContact O-CB 3.5Å; W171-S175 PolarHBondContact O-N 3.24Å; L172-S175 PolarHBondContact O-N 2.84Å; S175-L179 VanDerWaalsContact O-CB 3.23Å; S175-L179 WeakPolarHBondContact O-CB 3.44Å; S175-L179 PolarHBondContact O-N 3Å
176	S	89.3	Confident	90.4	Very high	10 Å²	10	61.3 Å²	61.3	7%	0.07	31%	0.307	C	S	.	.	H	α-helix	trans	-68.4	-35.9	177.5	60.8	0	0	0	0	112.4	L172 F173 L179 L180 M216 H220	L172-S176 PolarHBondContact O-N 3.36Å; L172-S176 PolarHBondContact O-OG 3Å; L172-S176 VanDerWaalsContact O-OG 3.14Å; F173-S176 PolarHBondContact O-OG 3.11Å; S176-L179 PolarHBondContact O-N 2.81Å; S176-L180 WeakPolarHBondContact O-CB 3.19Å; S176-L180 PolarHBondContact O-N 3.45Å; S176-M216 VanDerWaalsContact OG-CE 3.31Å; S176-M216 WeakPolarHBondContact OG-CE 3.46Å; S176-M216 PolarHBondContact OG-SD 3.16Å; S176-H220 PolarHBondContact OG-CE1 3.12Å
177	L	93	Very high	90.8	Very high	62 Å²	62	54.7 Å²	54.7	33%	0.325	28%	0.277	S	S	.	.	H	α-helix	trans	-65.1	-50.6	176.6	-175.4	158.4	0	0	0	110.4	F173 L174 L179 L180 F181 M216	F173-L177 HydrophobicContact CE1-CD1 3.78Å; F173-L177 HydrophobicContact CZ-CD1 4.27Å; F173-L177 WeakPolarHBondContact O-CB 3.48Å; F173-L177 PolarHBondContact O-N 3.37Å; L174-L177 PolarHBondContact O-N 2.91Å; L177-L179 PolarHBondContact O-N 3.44Å; L177-L180 PolarHBondContact O-N 3.48Å; L177-F181 HydrophobicContact CD2-CD2 4.28Å; L177-F181 HydrophobicContact CG-CD2 3.96Å; L177-F181 HydrophobicContact CG-CE2 4.13Å; L177-F181 WeakPolarHBondContact O-CB 3.27Å; L177-F181 VanDerWaalsContact O-CD2 3.3Å; L177-F181 WeakPolarHBondContact O-CD2 3.21Å; L177-F181 PolarHBondContact O-N 3.39Å; L177-M216 HydrophobicContact CB-CE 4.11Å; L177-M216 HydrophobicContact CB-SD 4.09Å
178	L	91.9	Very high	91.1	Very high	98 Å²	98	52.5 Å²	52.5	51%	0.513	26%	0.263	S	S	.	.	H	α-helix	trans	-54.8	-47.8	175.8	-177.1	76.8	0	0	0	109.7	L174 F182	L174-L178 WeakPolarHBondContact O-CB 3.12Å; L174-L178 PolarHBondContact O-N 3.5Å; L178-F182 HydrophobicContact CD1-CB 4.22Å; L178-F182 WeakPolarHBondContact O-CA 3.18Å; L178-F182 WeakPolarHBondContact O-CB 3.25Å; L178-F182 PolarHBondContact O-N 2.89Å
179	L	90.6	Very high	91.4	Very high	16 Å²	16	55.1 Å²	55.1	8%	0.084	28%	0.275	C	S	.	.	I	π-helix	trans	-64.8	-50.7	-175.9	-168.5	170.4	0	0	0	112.2	S175 S176 L177 F183 I235 L238 M239	S175-L179 VanDerWaalsContact O-CB 3.23Å; S175-L179 WeakPolarHBondContact O-CB 3.44Å; S175-L179 PolarHBondContact O-N 3Å; S176-L179 PolarHBondContact O-N 2.81Å; L177-L179 PolarHBondContact O-N 3.44Å; L179-F183 HydrophobicContact CB-CD2 4.34Å; L179-F183 HydrophobicContact CG-CD2 4.12Å; L179-F183 WeakPolarHBondContact O-CB 3.43Å; L179-F183 PolarHBondContact O-N 3.03Å; L179-I235 HydrophobicContact CD1-CG2 3.77Å; L179-I235 HydrophobicContact CD2-CB 4.16Å; L179-I235 HydrophobicContact CD2-CG1 3.91Å; L179-I235 HydrophobicContact CD2-CG2 3.87Å; L179-I235 HydrophobicContact CG-CG2 4.49Å; L179-L238 HydrophobicContact CD2-CB 4.25Å; L179-L238 HydrophobicContact CD2-CD1 4.36Å; L179-M239 HydrophobicContact CD1-CG 3.46Å; L179-M239 VanDerWaalsContact CD1-CG 3.46Å; L179-M239 HydrophobicContact CD1-SD 3.39Å; L179-M239 WeakPolarHBondContact CD1-SD 3.5Å; L179-M239 HydrophobicContact CG-CG 4.16Å; L179-M239 HydrophobicContact CG-SD 3.87Å
180	L	92.8	Very high	91.9	Very high	0 Å²	0	50 Å²	50	0%	0	25%	0.251	C	S	.	.	I	π-helix	trans	-69.3	-33.9	-177.4	-82.3	175.9	0	0	0	113.8	S176 L177 S184 F211 M216 I219 Y231 I235	S176-L180 WeakPolarHBondContact O-CB 3.19Å; S176-L180 PolarHBondContact O-N 3.45Å; L177-L180 PolarHBondContact O-N 3.48Å; L180-S184 WeakPolarHBondContact O-CB 2.98Å; L180-S184 PolarHBondContact O-OG 2.99Å; L180-F211 HydrophobicContact CD2-CE1 3.63Å; L180-F211 HydrophobicContact CD2-CZ 4.13Å; L180-M216 HydrophobicContact CD1-CG 4.28Å; L180-M216 HydrophobicContact CD1-SD 4.06Å; L180-I219 HydrophobicContact CD1-CD1 3.85Å; L180-Y231 HydrophobicContact CD2-CD1 4.17Å; L180-I235 HydrophobicContact CD1-CD1 4.13Å; L180-I235 HydrophobicContact CD2-CD1 3.89Å; L180-I235 HydrophobicContact CD2-CG1 3.64Å; L180-I235 HydrophobicContact CG-CD1 3.84Å; L180-I235 HydrophobicContact CG-CG1 4.06Å
181	F	95.4	Very high	92.2	Very high	44 Å²	44	49.4 Å²	49.4	19%	0.193	24%	0.24	C	C	.	.	I	π-helix	trans	-89.5	-53.2	-178.9	-75.2	-97.8	0	0	0	111.3	L177 F185 V208 W209 G212 V213 M216	L177-F181 HydrophobicContact CD2-CD2 4.28Å; L177-F181 HydrophobicContact CG-CD2 3.96Å; L177-F181 HydrophobicContact CG-CE2 4.13Å; L177-F181 WeakPolarHBondContact O-CB 3.27Å; L177-F181 VanDerWaalsContact O-CD2 3.3Å; L177-F181 WeakPolarHBondContact O-CD2 3.21Å; L177-F181 PolarHBondContact O-N 3.39Å; F181-F185 WeakPolarHBondContact O-CB 3.46Å; F181-F185 PolarHBondContact O-N 2.84Å; F181-V208 HydrophobicContact CD1-CG1 4.3Å; F181-W209 HydrophobicContact CE1-CE3 4.1Å; F181-G212 VanDerWaalsContact CE2-C 3.46Å; F181-V213 HydrophobicContact CE1-CG2 4.39Å; F181-V213 HydrophobicContact CZ-CG2 3.86Å; F181-M216 HydrophobicContact CE2-CG 3.99Å
182	F	94.1	Very high	92.4	Very high	108 Å²	108	47 Å²	47	47%	0.474	23%	0.232	S	C	.	.	I	π-helix	trans	-71.8	-49.4	-172.4	-175.6	-104.9	0	0	0	112.2	L178 F185 I186	L178-F182 HydrophobicContact CD1-CB 4.22Å; L178-F182 WeakPolarHBondContact O-CA 3.18Å; L178-F182 WeakPolarHBondContact O-CB 3.25Å; L178-F182 PolarHBondContact O-N 2.89Å; F182-F185 WeakPolarHBondContact O-CB 3.4Å; F182-F185 PolarHBondContact O-N 2.96Å; F182-I186 HydrophobicContact CD1-CD1 3.89Å; F182-I186 HydrophobicContact CE1-CD1 3.42Å; F182-I186 VanDerWaalsContact CE1-CD1 3.42Å; F182-I186 HydrophobicContact CE2-CD1 4.31Å; F182-I186 HydrophobicContact CZ-CD1 3.67Å; F182-I186 WeakPolarHBondContact O-CG1 3.43Å; F182-I186 PolarHBondContact O-N 2.6Å; F182-I186 VanDerWaalsContact O-N 3.12Å
183	F	93.3	Very high	92.7	Very high	38 Å²	38	51.6 Å²	51.6	17%	0.167	25%	0.251	C	S	.	.	I	π-helix	trans	-73.2	-33.4	-179.5	-67.2	-60.6	0	0	0	112.5	L179 F185 I186 Y187 V242	L179-F183 HydrophobicContact CB-CD2 4.34Å; L179-F183 HydrophobicContact CG-CD2 4.12Å; L179-F183 WeakPolarHBondContact O-CB 3.43Å; L179-F183 PolarHBondContact O-N 3.03Å; F183-F185 VanDerWaalsContact C-N 3.33Å; F183-I186 HydrophobicContact CD1-CD1 4.46Å; F183-I186 PolarHBondContact O-N 3.41Å; F183-Y187 VanDerWaalsContact O-CB 3.25Å; F183-Y187 WeakPolarHBondContact O-CB 3.17Å; F183-Y187 PolarHBondContact O-N 3.36Å; F183-V242 HydrophobicContact CD1-CG2 3.42Å; F183-V242 VanDerWaalsContact CD1-CG2 3.42Å; F183-V242 HydrophobicContact CD2-CG2 4.1Å; F183-V242 HydrophobicContact CE1-CG1 4.24Å; F183-V242 HydrophobicContact CE1-CG2 3.43Å; F183-V242 VanDerWaalsContact CE1-CG2 3.43Å; F183-V242 HydrophobicContact CE2-CG2 4.14Å; F183-V242 HydrophobicContact CG-CG2 3.79Å; F183-V242 HydrophobicContact CZ-CG1 4.13Å; F183-V242 HydrophobicContact CZ-CG2 3.82Å
184	S	94.2	Very high	92.9	Very high	4 Å²	4	49.5 Å²	49.5	3%	0.028	25%	0.246	C	C	.	.	H	α-helix	trans	-66.4	-36.4	173.1	-53.9	0	0	0	0	112.4	L180 Y187 L188 F211 L238	L180-S184 WeakPolarHBondContact O-CB 2.98Å; L180-S184 PolarHBondContact O-OG 2.99Å; S184-Y187 PolarHBondContact O-N 2.98Å; S184-L188 WeakPolarHBondContact O-CB 3.49Å; S184-L188 PolarHBondContact O-N 2.9Å; S184-F211 WeakPolarHBondContact OG-CE1 3.33Å; S184-L238 WeakPolarHBondContact OG-CD1 3.45Å
185	F	94.9	Very high	93	Very high	65 Å²	65	51.3 Å²	51.3	29%	0.285	25%	0.246	S	C	.	.	H	α-helix	trans	-60	-50.4	172.8	172.3	-97.8	0	0	0	111.2	F181 F182 F183 Y187 L188 Q189 L204 V208	F181-F185 WeakPolarHBondContact O-CB 3.46Å; F181-F185 PolarHBondContact O-N 2.84Å; F182-F185 WeakPolarHBondContact O-CB 3.4Å; F182-F185 PolarHBondContact O-N 2.96Å; F183-F185 VanDerWaalsContact C-N 3.33Å; F185-Y187 VanDerWaalsContact C-N 3.33Å; F185-Y187 PolarHBondContact O-N 3.27Å; F185-L188 PolarHBondContact O-N 3.28Å; F185-Q189 VanDerWaalsContact O-CB 3.29Å; F185-Q189 WeakPolarHBondContact O-CB 3.28Å; F185-Q189 PolarHBondContact O-N 3.11Å; F185-L204 HydrophobicContact CD2-CD2 3.95Å; F185-L204 HydrophobicContact CD2-CG 4.25Å; F185-L204 HydrophobicContact CE2-CD2 3.47Å; F185-L204 VanDerWaalsContact CE2-CD2 3.47Å; F185-L204 HydrophobicContact CE2-CG 4.15Å; F185-L204 HydrophobicContact CZ-CD2 4.29Å; F185-V208 HydrophobicContact CB-CG1 4.28Å; F185-V208 HydrophobicContact CB-CG2 4.28Å; F185-V208 HydrophobicContact CD2-CG2 4.34Å
186	I	93	Very high	93.2	Very high	34 Å²	34	55.6 Å²	55.6	17%	0.174	27%	0.265	C	S	.	.	H	α-helix	trans	-60.4	-44.7	177.2	-65.8	170.8	0	0	0	110.6	F182 F183 Q189 E190	F182-I186 HydrophobicContact CD1-CD1 3.89Å; F182-I186 HydrophobicContact CE1-CD1 3.42Å; F182-I186 VanDerWaalsContact CE1-CD1 3.42Å; F182-I186 HydrophobicContact CE2-CD1 4.31Å; F182-I186 HydrophobicContact CZ-CD1 3.67Å; F182-I186 WeakPolarHBondContact O-CG1 3.43Å; F182-I186 PolarHBondContact O-N 2.6Å; F182-I186 VanDerWaalsContact O-N 3.12Å; F183-I186 HydrophobicContact CD1-CD1 4.46Å; F183-I186 PolarHBondContact O-N 3.41Å; I186-Q189 PolarHBondContact O-N 3.49Å; I186-E190 WeakPolarHBondContact O-CB 3.36Å; I186-E190 PolarHBondContact O-N 2.95Å
187	Y	94.5	Very high	93.4	Very high	49 Å²	49	58.8 Å²	58.8	19%	0.192	28%	0.284	C	S	.	.	H	α-helix	trans	-58.7	-53.8	178.9	173.3	-101.3	0	0	0	112	T104 Y111 F183 S184 F185 Q189 E190 V191 L238 L241	T104-Y187 HydrophobicContact CG2-CD2 4.32Å; T104-Y187 HydrophobicContact CG2-CE2 3.62Å; T104-Y187 PolarHBondContact OG1-OH 3.13Å; Y111-Y187 HydrophobicContact CE2-CD2 4.33Å; F183-Y187 VanDerWaalsContact O-CB 3.25Å; F183-Y187 WeakPolarHBondContact O-CB 3.17Å; F183-Y187 PolarHBondContact O-N 3.36Å; S184-Y187 PolarHBondContact O-N 2.98Å; F185-Y187 VanDerWaalsContact C-N 3.33Å; F185-Y187 PolarHBondContact O-N 3.27Å; Y187-Q189 VanDerWaalsContact C-N 3.35Å; Y187-Q189 PolarHBondContact O-N 3.39Å; Y187-E190 PolarHBondContact O-N 3.45Å; Y187-V191 HydrophobicContact CD1-CG2 4.4Å; Y187-V191 HydrophobicContact CD2-CG2 4.41Å; Y187-V191 HydrophobicContact CE1-CG2 4.04Å; Y187-V191 HydrophobicContact CE2-CG2 4.06Å; Y187-V191 VanDerWaalsContact O-CG2 3.29Å; Y187-V191 WeakPolarHBondContact O-CG2 3.13Å; Y187-V191 PolarHBondContact O-N 2.93Å; Y187-L238 HydrophobicContact CD2-CD2 4.28Å; Y187-L238 HydrophobicContact CG-CD2 3.98Å; Y187-L241 HydrophobicContact CD2-CD1 4.18Å; Y187-L241 HydrophobicContact CE2-CD1 4.16Å
188	L	94.4	Very high	93.3	Very high	33 Å²	33	61 Å²	61	17%	0.173	31%	0.311	C	S	.	.	H	α-helix	trans	-60.7	-43.7	178.7	-85.7	154.8	0	0	0	111.7	S184 F185 E190 V191 F192 L204 V207 V208	S184-L188 WeakPolarHBondContact O-CB 3.49Å; S184-L188 PolarHBondContact O-N 2.9Å; F185-L188 PolarHBondContact O-N 3.28Å; L188-E190 VanDerWaalsContact C-N 3.26Å; L188-E190 PolarHBondContact O-N 3.46Å; L188-V191 PolarHBondContact O-N 3.23Å; L188-F192 HydrophobicContact CB-CE2 4.16Å; L188-F192 HydrophobicContact CD2-CE2 3.8Å; L188-F192 HydrophobicContact CD2-CZ 4Å; L188-F192 WeakPolarHBondContact O-CD2 3.44Å; L188-F192 WeakPolarHBondContact O-CG 3.24Å; L188-F192 PolarHBondContact O-N 3.11Å; L188-L204 HydrophobicContact CB-CD1 3.83Å; L188-V207 HydrophobicContact CD1-CG1 4.16Å; L188-V208 HydrophobicContact CD1-CG2 3.72Å
189	Q	93.3	Very high	93.2	Very high	56 Å²	56	59.7 Å²	59.7	26%	0.262	30%	0.303	S	S	.	.	H	α-helix	trans	-57.9	-42.8	177.6	-175	-178.1	-8.5	0	0	111.2	F185 I186 Y187 F192 K193	F185-Q189 VanDerWaalsContact O-CB 3.29Å; F185-Q189 WeakPolarHBondContact O-CB 3.28Å; F185-Q189 PolarHBondContact O-N 3.11Å; I186-Q189 PolarHBondContact O-N 3.49Å; Y187-Q189 VanDerWaalsContact C-N 3.35Å; Y187-Q189 PolarHBondContact O-N 3.39Å; Q189-F192 PolarHBondContact O-N 3.21Å; Q189-K193 WeakPolarHBondContact O-CG 3.5Å; Q189-K193 PolarHBondContact O-N 2.89Å
190	E	92.9	Very high	93.4	Very high	22 Å²	22	62.9 Å²	62.9	10%	0.103	32%	0.32	C	S	.	.	H	α-helix	trans	-76.3	-32.3	-177.7	-157.9	56.4	-144.6	0	0	113.3	V108 F110 I186 Y187 L188 K193 T194	V108-E190 HydrophobicContact CG1-CB 4.17Å; V108-E190 HydrophobicContact CG1-CG 3.56Å; F110-E190 VanDerWaalsContact CB-CD 3.45Å; F110-E190 HydrophobicContact CB-CG 3.24Å; F110-E190 VanDerWaalsContact CB-OE1 3.31Å; F110-E190 WeakPolarHBondContact CB-OE1 3.42Å; F110-E190 HydrophobicContact CD1-CG 3.81Å; F110-E190 HydrophobicContact CD2-CG 4.17Å; F110-E190 HydrophobicContact CG-CG 3.49Å; F110-E190 VanDerWaalsContact CG-CG 3.49Å; I186-E190 WeakPolarHBondContact O-CB 3.36Å; I186-E190 PolarHBondContact O-N 2.95Å; Y187-E190 PolarHBondContact O-N 3.45Å; L188-E190 VanDerWaalsContact C-N 3.26Å; L188-E190 PolarHBondContact O-N 3.46Å; E190-K193 PolarHBondContact O-N 3.14Å; E190-K193 WeakPolarHBondContact OE2-CD 3.43Å; E190-K193 IonicContact OE2-NZ 3.49Å; E190-K193 PolarHBondContact OE2-NZ 3Å; E190-T194 WeakPolarHBondContact O-CB 3.32Å; E190-T194 PolarHBondContact O-N 2.95Å; E190-T194 PolarHBondContact O-OG1 3.31Å
191	V	93.9	Very high	93.4	Very high	24 Å²	24	71.4 Å²	71.4	15%	0.145	35%	0.354	C	S	.	.	H	α-helix	trans	-58.6	-51.2	167.7	167.8	0	0	0	0	109.8	V108 Y187 L188 K193 T194 Y195	V108-V191 HydrophobicContact CG2-CG2 3.99Å; Y187-V191 HydrophobicContact CD1-CG2 4.4Å; Y187-V191 HydrophobicContact CD2-CG2 4.41Å; Y187-V191 HydrophobicContact CE1-CG2 4.04Å; Y187-V191 HydrophobicContact CE2-CG2 4.06Å; Y187-V191 VanDerWaalsContact O-CG2 3.29Å; Y187-V191 WeakPolarHBondContact O-CG2 3.13Å; Y187-V191 PolarHBondContact O-N 2.93Å; L188-V191 PolarHBondContact O-N 3.23Å; V191-K193 PolarHBondContact O-N 2.9Å; V191-T194 WeakPolarHBondContact O-CB 3.37Å; V191-T194 PolarHBondContact O-N 3.22Å; V191-T194 VanDerWaalsContact O-N 3.13Å; V191-Y195 HydrophobicContact CG1-CD2 3.75Å; V191-Y195 HydrophobicContact CG1-CE2 3.88Å; V191-Y195 VanDerWaalsContact O-CD2 3.22Å; V191-Y195 WeakPolarHBondContact O-CD2 3.21Å; V191-Y195 PolarHBondContact O-N 3Å
192	F	93.6	Very high	93.4	Very high	43 Å²	43	76.4 Å²	76.4	19%	0.189	38%	0.376	C	S	.	.	H	α-helix	trans	-63.9	-37.9	-180	-68.2	-52.3	0	0	0	113.3	L188 Q189 T194 N196 V197 M199 L204	L188-F192 HydrophobicContact CB-CE2 4.16Å; L188-F192 HydrophobicContact CD2-CE2 3.8Å; L188-F192 HydrophobicContact CD2-CZ 4Å; L188-F192 WeakPolarHBondContact O-CD2 3.44Å; L188-F192 WeakPolarHBondContact O-CG 3.24Å; L188-F192 PolarHBondContact O-N 3.11Å; Q189-F192 PolarHBondContact O-N 3.21Å; F192-T194 VanDerWaalsContact C-N 3.34Å; F192-T194 PolarHBondContact O-N 2.91Å; F192-N196 PolarHBondContact O-N 3.5Å; F192-V197 HydrophobicContact CD1-CB 4.19Å; F192-V197 HydrophobicContact CD1-CG1 4.35Å; F192-V197 PolarHBondContact O-N 3.48Å; F192-M199 HydrophobicContact CD1-CE 4.15Å; F192-M199 HydrophobicContact CD2-CB 4.39Å; F192-M199 HydrophobicContact CD2-CE 4.47Å; F192-M199 HydrophobicContact CD2-SD 4.04Å; F192-M199 HydrophobicContact CE1-CE 3.38Å; F192-M199 HydrophobicContact CE1-SD 4.17Å; F192-M199 HydrophobicContact CE2-CE 3.77Å; F192-M199 HydrophobicContact CE2-SD 3.39Å; F192-M199 WeakPolarHBondContact CE2-SD 3.37Å; F192-M199 HydrophobicContact CG-CB 4.45Å; F192-M199 HydrophobicContact CZ-CE 3.17Å; F192-M199 HydrophobicContact CZ-SD 3.48Å; F192-M199 WeakPolarHBondContact CZ-SD 3.35Å; F192-L204 HydrophobicContact CD2-CD1 4.21Å; F192-L204 HydrophobicContact CE2-CD1 3.86Å
193	K	91.8	Very high	93.5	Very high	115 Å²	115	73.9 Å²	73.9	50%	0.5	37%	0.369	S	S	.	.	H	α-helix	trans	-61.1	-43	172.3	-74.1	-174.7	-155	148.3	0	112	Q189 E190 V191 N196	Q189-K193 WeakPolarHBondContact O-CG 3.5Å; Q189-K193 PolarHBondContact O-N 2.89Å; E190-K193 PolarHBondContact O-N 3.14Å; E190-K193 WeakPolarHBondContact OE2-CD 3.43Å; E190-K193 IonicContact OE2-NZ 3.49Å; E190-K193 PolarHBondContact OE2-NZ 3Å; V191-K193 PolarHBondContact O-N 2.9Å; K193-N196 PolarHBondContact O-N 3.41Å
194	T	92.6	Very high	93.5	Very high	51 Å²	51	72.5 Å²	72.5	31%	0.313	36%	0.363	S	S	.	.	H	α-helix	trans	-64.5	-44.4	-179.4	-62.1	0	0	0	0	111.6	S107 E190 V191 F192 N196	S107-T194 WeakPolarHBondContact O-CG2 3.17Å; E190-T194 WeakPolarHBondContact O-CB 3.32Å; E190-T194 PolarHBondContact O-N 2.95Å; E190-T194 PolarHBondContact O-OG1 3.31Å; V191-T194 WeakPolarHBondContact O-CB 3.37Å; V191-T194 PolarHBondContact O-N 3.22Å; V191-T194 VanDerWaalsContact O-N 3.13Å; F192-T194 VanDerWaalsContact C-N 3.34Å; F192-T194 PolarHBondContact O-N 2.91Å; T194-N196 PolarHBondContact O-N 2.98Å
195	Y	93.6	Very high	93.5	Very high	146 Å²	146	74.9 Å²	74.9	57%	0.573	38%	0.383	S	S	*	.	T	Hydrogen-bonded Turn	trans	-80.2	1.7	176.7	-70.2	-73.5	0	0	0	113.5	V191 V197	V191-Y195 HydrophobicContact CG1-CD2 3.75Å; V191-Y195 HydrophobicContact CG1-CE2 3.88Å; V191-Y195 VanDerWaalsContact O-CD2 3.22Å; V191-Y195 WeakPolarHBondContact O-CD2 3.21Å; V191-Y195 PolarHBondContact O-N 3Å; Y195-V197 PolarHBondContact O-N 3.35Å
196	N	94.2	Very high	93.6	Very high	150 Å²	150	75.5 Å²	75.5	80%	0.802	39%	0.389	S	S	*	.	T	Hydrogen-bonded Turn	trans	51.6	38.3	-178	-163.8	35.8	0	0	0	113.3	F192 K193 T194	F192-N196 PolarHBondContact O-N 3.5Å; K193-N196 PolarHBondContact O-N 3.41Å; T194-N196 PolarHBondContact O-N 2.98Å
197	V	93.5	Very high	93.8	Very high	76 Å²	76	76.8 Å²	76.8	46%	0.461	40%	0.398	S	S	.	.			trans	-96.6	118.6	178.4	177.7	0	0	0	0	108.7	F192 Y195 M199	F192-V197 HydrophobicContact CD1-CB 4.19Å; F192-V197 HydrophobicContact CD1-CG1 4.35Å; F192-V197 PolarHBondContact O-N 3.48Å; Y195-V197 PolarHBondContact O-N 3.35Å; V197-M199 PolarHBondContact O-N 3.43Å
198	A	90.9	Very high	93.9	Very high	108 Å²	108	75 Å²	75	89%	0.893	39%	0.392	S	S	*	.			trans	-75.4	104.5	174	0	0	0	0	0	109.9
199	M	90.3	Very high	94	Very high	71 Å²	71	81.4 Å²	81.4	35%	0.35	41%	0.414	S	S	.	.			trans	-111.6	135.7	172.4	-172.6	171	-69.9	0	0	109.8	F192 V197 T203 L204	F192-M199 HydrophobicContact CD1-CE 4.15Å; F192-M199 HydrophobicContact CD2-CB 4.39Å; F192-M199 HydrophobicContact CD2-CE 4.47Å; F192-M199 HydrophobicContact CD2-SD 4.04Å; F192-M199 HydrophobicContact CE1-CE 3.38Å; F192-M199 HydrophobicContact CE1-SD 4.17Å; F192-M199 HydrophobicContact CE2-CE 3.77Å; F192-M199 HydrophobicContact CE2-SD 3.39Å; F192-M199 WeakPolarHBondContact CE2-SD 3.37Å; F192-M199 HydrophobicContact CG-CB 4.45Å; F192-M199 HydrophobicContact CZ-CE 3.17Å; F192-M199 HydrophobicContact CZ-SD 3.48Å; F192-M199 WeakPolarHBondContact CZ-SD 3.35Å; V197-M199 PolarHBondContact O-N 3.43Å; M199-T203 HydrophobicContact CG-CG2 4.19Å; M199-T203 HydrophobicContact SD-CG2 3.99Å; M199-L204 HydrophobicContact SD-CB 4.39Å
200	D	94.2	Very high	94.1	Very high	84 Å²	84	83 Å²	83	45%	0.449	43%	0.425	S	S	.	.			trans	-74.4	151.7	176.3	66.2	-74.4	0	0	0	111.7	F202 T203 L204	D200-F202 PolarHBondContact O-N 3.36Å; D200-F202 WeakPolarHBondContact OD2-CB 3.17Å; D200-F202 PolarHBondContact OD2-N 3.25Å; D200-T203 VanDerWaalsContact CG-OG1 3.24Å; D200-T203 PolarHBondContact O-N 3.05Å; D200-T203 VanDerWaalsContact OD1-CB 3.24Å; D200-T203 WeakPolarHBondContact OD1-CB 3.12Å; D200-T203 PolarHBondContact OD1-OG1 3.47Å; D200-T203 PolarHBondContact OD2-N 3.34Å; D200-T203 PolarHBondContact OD2-OG1 2.88Å; D200-T203 VanDerWaalsContact OD2-OG1 3.08Å; D200-L204 PolarHBondContact O-N 3.34Å; D200-L204 VanDerWaalsContact O-N 3.11Å
201	Y	93.6	Very high	94.3	Very high	179 Å²	179	84.5 Å²	84.5	70%	0.702	43%	0.431	S	S	*	.	H	α-helix	trans	-62.9	-26	-178.8	-70.4	-69.6	0	0	0	113.5	A205	Y201-A205 WeakPolarHBondContact O-CB 3.41Å; Y201-A205 PolarHBondContact O-N 3.31Å
202	F	95.4	Very high	94.3	Very high	149 Å²	149	83.3 Å²	83.3	65%	0.654	42%	0.424	S	S	*	.	H	α-helix	trans	-73.2	-48	-179.1	-179.4	-100.1	0	0	0	111	D200 L204 A205 I206	D200-F202 PolarHBondContact O-N 3.36Å; D200-F202 WeakPolarHBondContact OD2-CB 3.17Å; D200-F202 PolarHBondContact OD2-N 3.25Å; F202-L204 VanDerWaalsContact C-N 3.34Å; F202-L204 PolarHBondContact O-N 2.93Å; F202-A205 PolarHBondContact O-N 2.53Å; F202-I206 HydrophobicContact CD1-CD1 3.83Å; F202-I206 HydrophobicContact CE1-CD1 3.34Å; F202-I206 HydrophobicContact CE1-CG1 4.44Å; F202-I206 HydrophobicContact CE2-CD1 4.37Å; F202-I206 HydrophobicContact CZ-CD1 3.65Å; F202-I206 WeakPolarHBondContact O-CG1 3.48Å; F202-I206 PolarHBondContact O-N 2.87Å
203	T	94.8	Very high	94.4	Very high	54 Å²	54	83.5 Å²	83.5	33%	0.331	43%	0.428	S	S	.	.	H	α-helix	trans	-58.1	-46.6	172.1	-59.2	0	0	0	0	111	M199 D200 A205 I206 V207	M199-T203 HydrophobicContact CG-CG2 4.19Å; M199-T203 HydrophobicContact SD-CG2 3.99Å; D200-T203 VanDerWaalsContact CG-OG1 3.24Å; D200-T203 PolarHBondContact O-N 3.05Å; D200-T203 VanDerWaalsContact OD1-CB 3.24Å; D200-T203 WeakPolarHBondContact OD1-CB 3.12Å; D200-T203 PolarHBondContact OD1-OG1 3.47Å; D200-T203 PolarHBondContact OD2-N 3.34Å; D200-T203 PolarHBondContact OD2-OG1 2.88Å; D200-T203 VanDerWaalsContact OD2-OG1 3.08Å; T203-A205 VanDerWaalsContact C-N 3.34Å; T203-A205 PolarHBondContact O-N 3.04Å; T203-I206 PolarHBondContact O-N 3.36Å; T203-V207 HydrophobicContact CG2-CG2 4.46Å; T203-V207 VanDerWaalsContact O-CG2 3.29Å; T203-V207 WeakPolarHBondContact O-CG2 3.42Å; T203-V207 PolarHBondContact O-N 3.23Å
204	L	94.3	Very high	94.6	Very high	9 Å²	9	80.6 Å²	80.6	5%	0.047	42%	0.42	C	S	.	.	H	α-helix	trans	-59.7	-43.6	177.4	-177.1	65.5	0	0	0	111.9	F185 L188 F192 M199 D200 F202 I206 V207 V208	F185-L204 HydrophobicContact CD2-CD2 3.95Å; F185-L204 HydrophobicContact CD2-CG 4.25Å; F185-L204 HydrophobicContact CE2-CD2 3.47Å; F185-L204 VanDerWaalsContact CE2-CD2 3.47Å; F185-L204 HydrophobicContact CE2-CG 4.15Å; F185-L204 HydrophobicContact CZ-CD2 4.29Å; L188-L204 HydrophobicContact CB-CD1 3.83Å; F192-L204 HydrophobicContact CD2-CD1 4.21Å; F192-L204 HydrophobicContact CE2-CD1 3.86Å; M199-L204 HydrophobicContact SD-CB 4.39Å; D200-L204 PolarHBondContact O-N 3.34Å; D200-L204 VanDerWaalsContact O-N 3.11Å; F202-L204 VanDerWaalsContact C-N 3.34Å; F202-L204 PolarHBondContact O-N 2.93Å; L204-I206 PolarHBondContact O-N 3.04Å; L204-V207 PolarHBondContact O-N 2.88Å; L204-V208 HydrophobicContact CD1-CG2 4.26Å; L204-V208 HydrophobicContact CG-CG2 4.47Å; L204-V208 WeakPolarHBondContact O-CB 3.07Å; L204-V208 WeakPolarHBondContact O-CG2 3.49Å; L204-V208 PolarHBondContact O-N 3.5Å
205	A	95	Very high	94.6	Very high	55 Å²	55	78.2 Å²	78.2	46%	0.455	41%	0.405	S	S	.	.	H	α-helix	trans	-62.7	-41.9	177.6	0	0	0	0	0	112	Y201 F202 T203 W209	Y201-A205 WeakPolarHBondContact O-CB 3.41Å; Y201-A205 PolarHBondContact O-N 3.31Å; F202-A205 PolarHBondContact O-N 2.53Å; T203-A205 VanDerWaalsContact C-N 3.34Å; T203-A205 PolarHBondContact O-N 3.04Å; A205-W209 WeakPolarHBondContact O-CB 3.14Å; A205-W209 PolarHBondContact O-N 3.37Å
206	I	96.8	Very high	94.5	Very high	78 Å²	78	72 Å²	72	40%	0.4	38%	0.382	S	S	.	.	H	α-helix	trans	-62.9	-45.2	175.8	-70.1	172.7	0	0	0	110.8	F202 T203 L204 W209 N210	F202-I206 HydrophobicContact CD1-CD1 3.83Å; F202-I206 HydrophobicContact CE1-CD1 3.34Å; F202-I206 HydrophobicContact CE1-CG1 4.44Å; F202-I206 HydrophobicContact CE2-CD1 4.37Å; F202-I206 HydrophobicContact CZ-CD1 3.65Å; F202-I206 WeakPolarHBondContact O-CG1 3.48Å; F202-I206 PolarHBondContact O-N 2.87Å; T203-I206 PolarHBondContact O-N 3.36Å; L204-I206 PolarHBondContact O-N 3.04Å; I206-W209 PolarHBondContact O-N 3.35Å; I206-N210 WeakPolarHBondContact CG2-ND2 3.43Å; I206-N210 PolarHBondContact O-N 3.45Å; I206-N210 PolarHBondContact O-ND2 3.23Å
207	V	96.1	Very high	94.4	Very high	61 Å²	61	68.7 Å²	68.7	37%	0.37	36%	0.363	S	S	.	.	H	α-helix	trans	-62.1	-50	179.8	171.7	0	0	0	0	110.7	L188 T203 L204 W209 N210 F211	L188-V207 HydrophobicContact CD1-CG1 4.16Å; T203-V207 HydrophobicContact CG2-CG2 4.46Å; T203-V207 VanDerWaalsContact O-CG2 3.29Å; T203-V207 WeakPolarHBondContact O-CG2 3.42Å; T203-V207 PolarHBondContact O-N 3.23Å; L204-V207 PolarHBondContact O-N 2.88Å; V207-W209 VanDerWaalsContact C-N 3.33Å; V207-W209 PolarHBondContact O-N 2.96Å; V207-N210 PolarHBondContact O-N 3.1Å; V207-F211 WeakPolarHBondContact O-CB 3.4Å; V207-F211 PolarHBondContact O-N 3.22Å
208	V	96.3	Very high	94.2	Very high	11 Å²	11	65.3 Å²	65.3	7%	0.067	34%	0.343	C	S	.	.	H	α-helix	trans	-64.3	-38.7	178.7	173.2	0	0	0	0	111.2	F181 F185 L188 L204 F211 G212	F181-V208 HydrophobicContact CD1-CG1 4.3Å; F185-V208 HydrophobicContact CB-CG1 4.28Å; F185-V208 HydrophobicContact CB-CG2 4.28Å; F185-V208 HydrophobicContact CD2-CG2 4.34Å; L188-V208 HydrophobicContact CD1-CG2 3.72Å; L204-V208 HydrophobicContact CD1-CG2 4.26Å; L204-V208 HydrophobicContact CG-CG2 4.47Å; L204-V208 WeakPolarHBondContact O-CB 3.07Å; L204-V208 WeakPolarHBondContact O-CG2 3.49Å; L204-V208 PolarHBondContact O-N 3.5Å; V208-F211 PolarHBondContact O-N 3.41Å; V208-G212 PolarHBondContact O-N 3.38Å
209	W	96.5	Very high	94	Very high	167 Å²	167	60.4 Å²	60.4	63%	0.633	30%	0.301	S	S	*	.	H	α-helix	trans	-61.5	-48.9	176.2	179.3	-93.5	0	0	0	111.8	F181 A205 I206 V207 G212 V213	F181-W209 HydrophobicContact CE1-CE3 4.1Å; A205-W209 WeakPolarHBondContact O-CB 3.14Å; A205-W209 PolarHBondContact O-N 3.37Å; I206-W209 PolarHBondContact O-N 3.35Å; V207-W209 VanDerWaalsContact C-N 3.33Å; V207-W209 PolarHBondContact O-N 2.96Å; W209-G212 PolarHBondContact O-N 2.86Å; W209-V213 HydrophobicContact CD2-CG2 3.95Å; W209-V213 HydrophobicContact CE3-CG2 4.46Å; W209-V213 HydrophobicContact CG-CG2 4.33Å; W209-V213 HydrophobicContact CH2-CG2 4.44Å; W209-V213 HydrophobicContact CZ2-CG2 3.92Å; W209-V213 WeakPolarHBondContact O-CB 3.47Å; W209-V213 VanDerWaalsContact O-CG2 3.29Å; W209-V213 WeakPolarHBondContact O-CG2 3.35Å; W209-V213 PolarHBondContact O-N 3.38Å
210	N	96.4	Very high	93.8	Very high	91 Å²	91	59.8 Å²	59.8	49%	0.487	30%	0.298	S	S	.	.	H	α-helix	trans	-61.6	-47.9	177.5	-80.4	-80.2	0	0	0	111.3	I206 V207 V214	I206-N210 WeakPolarHBondContact CG2-ND2 3.43Å; I206-N210 PolarHBondContact O-N 3.45Å; I206-N210 PolarHBondContact O-ND2 3.23Å; V207-N210 PolarHBondContact O-N 3.1Å; N210-V214 VanDerWaalsContact O-CB 3.27Å; N210-V214 WeakPolarHBondContact O-CB 3.26Å; N210-V214 WeakPolarHBondContact O-CG2 3.37Å; N210-V214 PolarHBondContact O-N 3.39Å
211	F	96.3	Very high	93.3	Very high	52 Å²	52	65.7 Å²	65.7	23%	0.228	31%	0.314	C	S	.	.	H	α-helix	trans	-59.6	-48.4	177.6	179	-94.8	0	0	0	112	L180 S184 V207 V208 G215 Y231 M234	L180-F211 HydrophobicContact CD2-CE1 3.63Å; L180-F211 HydrophobicContact CD2-CZ 4.13Å; S184-F211 WeakPolarHBondContact OG-CE1 3.33Å; V207-F211 WeakPolarHBondContact O-CB 3.4Å; V207-F211 PolarHBondContact O-N 3.22Å; V208-F211 PolarHBondContact O-N 3.41Å; F211-G215 PolarHBondContact O-N 3.46Å; F211-Y231 HydrophobicContact CD1-CE1 4.49Å; F211-Y231 AromaticContact CD2-CE1 3.78Å; F211-Y231 HydrophobicContact CD2-CE1 3.78Å; F211-Y231 HydrophobicContact CE1-CE1 4.24Å; F211-Y231 HydrophobicContact CE2-CD1 4.12Å; F211-Y231 AromaticContact CE2-CE1 3.5Å; F211-Y231 HydrophobicContact CE2-CE1 3.5Å; F211-Y231 HydrophobicContact CG-CE1 4.27Å; F211-Y231 HydrophobicContact CZ-CD1 4.04Å; F211-Y231 AromaticContact CZ-CE1 3.76Å; F211-Y231 HydrophobicContact CZ-CE1 3.76Å; F211-Y231 WeakPolarHBondContact O-CE1 3.42Å; F211-Y231 PolarHBondContact O-OH 3.33Å; F211-M234 HydrophobicContact CZ-CB 4.42Å
212	G	95.4	Very high	92.7	Very high	0 Å²	0	63.2 Å²	63.2	0%	0	31%	0.307	C	S	.	.	H	α-helix	trans	-66.8	-47.4	-177.8	0	0	0	0	0	112.9	F181 V208 W209 G215 M216	F181-G212 VanDerWaalsContact CE2-C 3.46Å; V208-G212 PolarHBondContact O-N 3.38Å; W209-G212 PolarHBondContact O-N 2.86Å; G212-G215 PolarHBondContact O-N 3.41Å; G212-M216 WeakPolarHBondContact O-CB 3.47Å; G212-M216 VanDerWaalsContact O-CG 3.26Å; G212-M216 WeakPolarHBondContact O-CG 3.48Å; G212-M216 PolarHBondContact O-N 2.88Å
213	V	95.5	Very high	92	Very high	47 Å²	47	57 Å²	57	29%	0.285	28%	0.284	S	S	.	.	H	α-helix	trans	-66.4	-46.5	-179.5	173.6	0	0	0	0	111.1	F181 W209 G215 M216 I217	F181-V213 HydrophobicContact CE1-CG2 4.39Å; F181-V213 HydrophobicContact CZ-CG2 3.86Å; W209-V213 HydrophobicContact CD2-CG2 3.95Å; W209-V213 HydrophobicContact CE3-CG2 4.46Å; W209-V213 HydrophobicContact CG-CG2 4.33Å; W209-V213 HydrophobicContact CH2-CG2 4.44Å; W209-V213 HydrophobicContact CZ2-CG2 3.92Å; W209-V213 WeakPolarHBondContact O-CB 3.47Å; W209-V213 VanDerWaalsContact O-CG2 3.29Å; W209-V213 WeakPolarHBondContact O-CG2 3.35Å; W209-V213 PolarHBondContact O-N 3.38Å; V213-G215 VanDerWaalsContact C-N 3.31Å; V213-G215 PolarHBondContact O-N 3.42Å; V213-M216 PolarHBondContact O-N 2.79Å; V213-I217 HydrophobicContact CG1-CD1 3.81Å; V213-I217 HydrophobicContact CG1-CG1 4.44Å; V213-I217 VanDerWaalsContact O-CG1 3.3Å; V213-I217 WeakPolarHBondContact O-CG1 2.97Å; V213-I217 PolarHBondContact O-N 3.11Å
214	V	95.4	Very high	91.8	Very high	54 Å²	54	58.3 Å²	58.3	33%	0.327	29%	0.294	S	S	.	.	H	α-helix	trans	-63.1	-40.7	177.8	175.7	0	0	0	0	110.4	N210 I217 C218 L227 Y231	N210-V214 VanDerWaalsContact O-CB 3.27Å; N210-V214 WeakPolarHBondContact O-CB 3.26Å; N210-V214 WeakPolarHBondContact O-CG2 3.37Å; N210-V214 PolarHBondContact O-N 3.39Å; V214-I217 PolarHBondContact O-N 3.09Å; V214-C218 WeakPolarHBondContact O-CB 3.5Å; V214-C218 PolarHBondContact O-N 3.23Å; V214-C218 PolarHBondContact O-SG 3.07Å; V214-L227 HydrophobicContact CG1-CD2 4.09Å; V214-Y231 WeakPolarHBondContact CB-OH 3.46Å; V214-Y231 HydrophobicContact CG1-CE2 3.86Å; V214-Y231 WeakPolarHBondContact CG1-OH 3.4Å
215	G	92.8	Very high	91.3	Very high	0 Å²	0	60.6 Å²	60.6	0%	0	31%	0.306	C	S	.	.	H	α-helix	trans	-60.4	-45.4	174	0	0	0	0	0	112.8	F211 G212 V213 I217 C218 I219 Y231	F211-G215 PolarHBondContact O-N 3.46Å; G212-G215 PolarHBondContact O-N 3.41Å; V213-G215 VanDerWaalsContact C-N 3.31Å; V213-G215 PolarHBondContact O-N 3.42Å; G215-I217 PolarHBondContact O-N 2.8Å; G215-C218 PolarHBondContact O-N 3.34Å; G215-I219 WeakPolarHBondContact O-CD1 3.45Å; G215-I219 VanDerWaalsContact O-CG1 3.24Å; G215-I219 WeakPolarHBondContact O-CG1 3.43Å; G215-I219 PolarHBondContact O-N 3.11Å; G215-Y231 VanDerWaalsContact CA-CD1 3.48Å
216	M	91.6	Very high	91	Very high	15 Å²	15	66.7 Å²	66.7	7%	0.074	32%	0.317	C	S	.	.	H	α-helix	trans	-62.2	-41.9	176.9	-73	-57.8	-64.3	0	0	112.3	F173 S176 L177 L180 F181 G212 V213 I219 H220	F173-M216 HydrophobicContact CD1-CE 4.23Å; F173-M216 HydrophobicContact CD2-CE 3.25Å; F173-M216 HydrophobicContact CE1-CE 4.18Å; F173-M216 HydrophobicContact CE2-CE 3.2Å; F173-M216 HydrophobicContact CG-CE 3.8Å; F173-M216 HydrophobicContact CZ-CE 3.69Å; S176-M216 VanDerWaalsContact OG-CE 3.31Å; S176-M216 WeakPolarHBondContact OG-CE 3.46Å; S176-M216 PolarHBondContact OG-SD 3.16Å; L177-M216 HydrophobicContact CB-CE 4.11Å; L177-M216 HydrophobicContact CB-SD 4.09Å; L180-M216 HydrophobicContact CD1-CG 4.28Å; L180-M216 HydrophobicContact CD1-SD 4.06Å; F181-M216 HydrophobicContact CE2-CG 3.99Å; G212-M216 WeakPolarHBondContact O-CB 3.47Å; G212-M216 VanDerWaalsContact O-CG 3.26Å; G212-M216 WeakPolarHBondContact O-CG 3.48Å; G212-M216 PolarHBondContact O-N 2.88Å; V213-M216 PolarHBondContact O-N 2.79Å; M216-I219 PolarHBondContact O-N 3.33Å; M216-H220 WeakPolarHBondContact O-CB 3.4Å; M216-H220 PolarHBondContact O-N 3.22Å
217	I	90.8	Very high	90.7	Very high	82 Å²	82	66.3 Å²	66.3	42%	0.421	32%	0.315	S	S	.	.	H	α-helix	trans	-63.4	-43.6	174.9	-66.4	166.8	0	0	0	110.5	V213 V214 G215 I219 W221	V213-I217 HydrophobicContact CG1-CD1 3.81Å; V213-I217 HydrophobicContact CG1-CG1 4.44Å; V213-I217 VanDerWaalsContact O-CG1 3.3Å; V213-I217 WeakPolarHBondContact O-CG1 2.97Å; V213-I217 PolarHBondContact O-N 3.11Å; V214-I217 PolarHBondContact O-N 3.09Å; G215-I217 PolarHBondContact O-N 2.8Å; I217-I219 VanDerWaalsContact C-N 3.32Å; I217-I219 PolarHBondContact O-N 2.8Å; I217-W221 HydrophobicContact CG2-CB 4.13Å; I217-W221 CarbonylContact O-C 3.13Å; I217-W221 WeakPolarHBondContact O-CA 3.39Å; I217-W221 WeakPolarHBondContact O-CB 3.05Å; I217-W221 PolarHBondContact O-N 3.42Å; I217-W221 VanDerWaalsContact O-O 3.1Å
218	C	89.4	Confident	90.4	Very high	4 Å²	4	65.5 Å²	65.5	3%	0.027	31%	0.308	C	S	.	.	H	α-helix	trans	-68.4	-28.8	-178.8	-67	0	0	0	0	113.7	V214 G215 L227 Q228 Y231	V214-C218 WeakPolarHBondContact O-CB 3.5Å; V214-C218 PolarHBondContact O-N 3.23Å; V214-C218 PolarHBondContact O-SG 3.07Å; G215-C218 PolarHBondContact O-N 3.34Å; C218-L227 VanDerWaalsContact SG-CD2 3.52Å; C218-Q228 HydrophobicContact CB-CB 4.5Å; C218-Q228 WeakPolarHBondContact O-CG 3.19Å; C218-Y231 HydrophobicContact CB-CD2 4.04Å
219	I	86.9	Confident	90.1	Very high	5 Å²	5	65.6 Å²	65.6	3%	0.026	31%	0.307	C	S	.	.	H	α-helix	trans	-90.7	-44	-176.9	-63.5	164.1	0	0	0	111.9	L180 G215 M216 I217 L232 I235 P290 A291	L180-I219 HydrophobicContact CD1-CD1 3.85Å; G215-I219 WeakPolarHBondContact O-CD1 3.45Å; G215-I219 VanDerWaalsContact O-CG1 3.24Å; G215-I219 WeakPolarHBondContact O-CG1 3.43Å; G215-I219 PolarHBondContact O-N 3.11Å; M216-I219 PolarHBondContact O-N 3.33Å; I217-I219 VanDerWaalsContact C-N 3.32Å; I217-I219 PolarHBondContact O-N 2.8Å; I219-L232 HydrophobicContact CG1-CD1 4.06Å; I219-I235 HydrophobicContact CD1-CD1 3.27Å; I219-P290 WeakPolarHBondContact O-CB 3.36Å; I219-A291 HydrophobicContact CG2-CB 3.71Å
220	H	85.9	Confident	89.9	Confident	58 Å²	58	59.8 Å²	59.8	27%	0.269	30%	0.295	S	S	.	.	H	α-helix	trans	-102.5	-13.8	-173.2	-68.5	79.5	0	0	0	113.4	S176 M216	S176-H220 PolarHBondContact OG-CE1 3.12Å; M216-H220 WeakPolarHBondContact O-CB 3.4Å; M216-H220 PolarHBondContact O-N 3.22Å
221	W	84.6	Confident	89.8	Confident	208 Å²	208	56.4 Å²	56.4	79%	0.788	28%	0.275	S	S	*	.	S	Bend	trans	-123.8	-174.1	178.3	-140.6	-86.3	0	0	0	110.4	I217 G223	I217-W221 HydrophobicContact CG2-CB 4.13Å; I217-W221 CarbonylContact O-C 3.13Å; I217-W221 WeakPolarHBondContact O-CA 3.39Å; I217-W221 WeakPolarHBondContact O-CB 3.05Å; I217-W221 PolarHBondContact O-N 3.42Å; I217-W221 VanDerWaalsContact O-O 3.1Å; W221-G223 PolarHBondContact O-N 3.34Å
222	K	81.2	Confident	89.5	Confident	128 Å²	128	54.2 Å²	54.2	56%	0.557	27%	0.266	S	S	*	.			trans	-74.3	111.1	176.9	-165.3	162	-179.7	72.9	0	110.6	W300	K222-W300 HydrophobicContact CB-CH2 4.42Å; K222-W300 HydrophobicContact CB-CZ2 3.84Å; K222-W300 HydrophobicContact CD-CH2 3.81Å; K222-W300 HydrophobicContact CD-CZ2 3.56Å; K222-W300 HydrophobicContact CG-CH2 4.22Å; K222-W300 HydrophobicContact CG-CZ2 3.51Å
223	G	80.3	Confident	89.4	Confident	17 Å²	17	54.8 Å²	54.8	18%	0.175	27%	0.269	C	S	.	.			trans	-127.5	166.1	173	0	0	0	0	0	112.8	W221	W221-G223 PolarHBondContact O-N 3.34Å
224	P	89.8	Confident	89.4	Confident	83 Å²	83	54.9 Å²	54.9	54%	0.539	27%	0.267	S	S	.	.			trans	-69.1	135.7	174	23.6	-25.4	0	0	0	110.6	R226 L227 Q228	P224-R226 VanDerWaalsContact C-N 3.33Å; P224-R226 PolarHBondContact O-N 2.75Å; P224-L227 HydrophobicContact CG-CB 3.75Å; P224-L227 HydrophobicContact CG-CD2 4.02Å; P224-L227 WeakPolarHBondContact O-CB 3.35Å; P224-L227 PolarHBondContact O-N 3.46Å; P224-Q228 PolarHBondContact O-N 3.12Å
225	L	84.6	Confident	89.2	Confident	56 Å²	56	53.4 Å²	53.4	29%	0.293	26%	0.257	S	S	.	.	H	α-helix	trans	-56.2	-42.7	-169.2	-175.2	148.5	0	0	0	113.3	L227 Q228 Q229 M298	L225-L227 VanDerWaalsContact C-N 3.33Å; L225-L227 PolarHBondContact O-N 3.41Å; L225-Q228 PolarHBondContact O-N 2.79Å; L225-Q229 VanDerWaalsContact CD2-CD 3.49Å; L225-Q229 HydrophobicContact CD2-CG 4.21Å; L225-Q229 VanDerWaalsContact CD2-NE2 3.31Å; L225-Q229 WeakPolarHBondContact O-CG 3.09Å; L225-Q229 PolarHBondContact O-N 2.7Å; L225-M298 HydrophobicContact CD1-CB 4.19Å; L225-M298 HydrophobicContact CD1-CG 3.78Å
226	R	88.3	Confident	89.3	Confident	184 Å²	184	53.4 Å²	53.4	69%	0.694	26%	0.257	S	S	*	.	H	α-helix	trans	-64.9	-36.2	178.4	-64.4	-58.2	-172.6	176.5	2.9	112.9	P224 Q229 A230	P224-R226 VanDerWaalsContact C-N 3.33Å; P224-R226 PolarHBondContact O-N 2.75Å; R226-Q229 PolarHBondContact O-N 3.17Å; R226-A230 PolarHBondContact O-N 2.88Å
227	L	90.8	Very high	89.5	Confident	69 Å²	69	52.8 Å²	52.8	36%	0.361	25%	0.254	S	S	.	.	H	α-helix	trans	-72.8	-41.2	178.6	-170.3	59.4	0	0	0	110.6	V214 C218 P224 L225 Q229 A230 Y231	V214-L227 HydrophobicContact CG1-CD2 4.09Å; C218-L227 VanDerWaalsContact SG-CD2 3.52Å; P224-L227 HydrophobicContact CG-CB 3.75Å; P224-L227 HydrophobicContact CG-CD2 4.02Å; P224-L227 WeakPolarHBondContact O-CB 3.35Å; P224-L227 PolarHBondContact O-N 3.46Å; L225-L227 VanDerWaalsContact C-N 3.33Å; L225-L227 PolarHBondContact O-N 3.41Å; L227-Q229 VanDerWaalsContact C-N 3.35Å; L227-Q229 PolarHBondContact O-N 3.4Å; L227-A230 PolarHBondContact O-N 3.42Å; L227-Y231 HydrophobicContact CD1-CD2 4.14Å; L227-Y231 HydrophobicContact CD1-CE2 3.76Å; L227-Y231 HydrophobicContact CD2-CE2 4.34Å; L227-Y231 HydrophobicContact CG-CD2 3.96Å; L227-Y231 HydrophobicContact CG-CE2 3.77Å; L227-Y231 VanDerWaalsContact O-CD2 3.26Å; L227-Y231 WeakPolarHBondContact O-CD2 3.44Å; L227-Y231 PolarHBondContact O-N 3.01Å
228	Q	89.9	Confident	89.7	Confident	45 Å²	45	49.1 Å²	49.1	21%	0.21	24%	0.235	C	C	.	.	H	α-helix	trans	-56.7	-49.1	171.2	-179.7	177.3	-8.1	0	0	110.7	C218 P224 L225 A230 Y231 L232	C218-Q228 HydrophobicContact CB-CB 4.5Å; C218-Q228 WeakPolarHBondContact O-CG 3.19Å; P224-Q228 PolarHBondContact O-N 3.12Å; L225-Q228 PolarHBondContact O-N 2.79Å; Q228-A230 VanDerWaalsContact C-N 3.33Å; Q228-A230 PolarHBondContact O-N 2.95Å; Q228-Y231 PolarHBondContact O-N 3.22Å; Q228-L232 HydrophobicContact CG-CD1 3.75Å; Q228-L232 WeakPolarHBondContact O-CD1 3.29Å; Q228-L232 PolarHBondContact O-N 2.82Å
229	Q	90.4	Very high	89.8	Confident	12 Å²	12	50.8 Å²	50.8	6%	0.056	24%	0.243	C	C	.	.	H	α-helix	trans	-56	-44.6	175.4	-73.1	178.2	-19.1	0	0	112.3	L225 R226 L227 L232 I233 Y294 S295 S296	L225-Q229 VanDerWaalsContact CD2-CD 3.49Å; L225-Q229 HydrophobicContact CD2-CG 4.21Å; L225-Q229 VanDerWaalsContact CD2-NE2 3.31Å; L225-Q229 WeakPolarHBondContact O-CG 3.09Å; L225-Q229 PolarHBondContact O-N 2.7Å; R226-Q229 PolarHBondContact O-N 3.17Å; L227-Q229 VanDerWaalsContact C-N 3.35Å; L227-Q229 PolarHBondContact O-N 3.4Å; Q229-L232 PolarHBondContact O-N 3.11Å; Q229-I233 VanDerWaalsContact O-CG1 3.27Å; Q229-I233 WeakPolarHBondContact O-CG1 3.47Å; Q229-I233 PolarHBondContact O-N 3.43Å; Q229-Y294 HydrophobicContact CB-CE2 3.8Å; Q229-Y294 HydrophobicContact CG-CE2 3.67Å; Q229-Y294 WeakPolarHBondContact CG-OH 3.49Å; Q229-Y294 PolarHBondContact NE2-OH 2.79Å; Q229-S295 PolarHBondContact NE2-O 2.97Å; Q229-S296 PolarHBondContact NE2-O 2.97Å; Q229-S296 VanDerWaalsContact NE2-O 3.16Å
230	A	92.5	Very high	90.2	Very high	45 Å²	45	50.6 Å²	50.6	37%	0.372	24%	0.242	S	C	.	.	H	α-helix	trans	-61.7	-43.9	176.9	0	0	0	0	0	112.5	R226 L227 Q228 I233 M234	R226-A230 PolarHBondContact O-N 2.88Å; L227-A230 PolarHBondContact O-N 3.42Å; Q228-A230 VanDerWaalsContact C-N 3.33Å; Q228-A230 PolarHBondContact O-N 2.95Å; A230-I233 PolarHBondContact O-N 3.16Å; A230-M234 WeakPolarHBondContact O-CG 3.32Å; A230-M234 PolarHBondContact O-N 2.88Å
231	Y	93.2	Very high	90.6	Very high	21 Å²	21	48 Å²	48	8%	0.082	23%	0.23	C	C	.	.	H	α-helix	trans	-64.8	-39.3	175.2	-84.5	-73	0	0	0	112.5	L180 F211 V214 G215 C218 L227 Q228 I233 M234 I235	L180-Y231 HydrophobicContact CD2-CD1 4.17Å; F211-Y231 HydrophobicContact CD1-CE1 4.49Å; F211-Y231 AromaticContact CD2-CE1 3.78Å; F211-Y231 HydrophobicContact CD2-CE1 3.78Å; F211-Y231 HydrophobicContact CE1-CE1 4.24Å; F211-Y231 HydrophobicContact CE2-CD1 4.12Å; F211-Y231 AromaticContact CE2-CE1 3.5Å; F211-Y231 HydrophobicContact CE2-CE1 3.5Å; F211-Y231 HydrophobicContact CG-CE1 4.27Å; F211-Y231 HydrophobicContact CZ-CD1 4.04Å; F211-Y231 AromaticContact CZ-CE1 3.76Å; F211-Y231 HydrophobicContact CZ-CE1 3.76Å; F211-Y231 WeakPolarHBondContact O-CE1 3.42Å; F211-Y231 PolarHBondContact O-OH 3.33Å; V214-Y231 WeakPolarHBondContact CB-OH 3.46Å; V214-Y231 HydrophobicContact CG1-CE2 3.86Å; V214-Y231 WeakPolarHBondContact CG1-OH 3.4Å; G215-Y231 VanDerWaalsContact CA-CD1 3.48Å; C218-Y231 HydrophobicContact CB-CD2 4.04Å; L227-Y231 HydrophobicContact CD1-CD2 4.14Å; L227-Y231 HydrophobicContact CD1-CE2 3.76Å; L227-Y231 HydrophobicContact CD2-CE2 4.34Å; L227-Y231 HydrophobicContact CG-CD2 3.96Å; L227-Y231 HydrophobicContact CG-CE2 3.77Å; L227-Y231 VanDerWaalsContact O-CD2 3.26Å; L227-Y231 WeakPolarHBondContact O-CD2 3.44Å; L227-Y231 PolarHBondContact O-N 3.01Å; Q228-Y231 PolarHBondContact O-N 3.22Å; Y231-I233 VanDerWaalsContact C-N 3.34Å; Y231-I233 PolarHBondContact O-N 3.23Å; Y231-M234 PolarHBondContact O-N 3.08Å; Y231-I235 WeakPolarHBondContact O-CB 3.24Å; Y231-I235 VanDerWaalsContact O-CG1 3.32Å; Y231-I235 WeakPolarHBondContact O-CG1 3.45Å; Y231-I235 PolarHBondContact O-N 3.25Å
232	L	90.8	Very high	90.9	Very high	5 Å²	5	38.9 Å²	38.9	3%	0.026	20%	0.197	C	C	.	.	H	α-helix	trans	-61	-44	175.6	-93.6	69.4	0	0	0	111.2	I219 Q228 Q229 I235 S236 I293 Y294 L392	I219-L232 HydrophobicContact CG1-CD1 4.06Å; Q228-L232 HydrophobicContact CG-CD1 3.75Å; Q228-L232 WeakPolarHBondContact O-CD1 3.29Å; Q228-L232 PolarHBondContact O-N 2.82Å; Q229-L232 PolarHBondContact O-N 3.11Å; L232-I235 PolarHBondContact O-N 3.46Å; L232-S236 PolarHBondContact O-N 3.41Å; L232-S236 PolarHBondContact O-OG 2.93Å; L232-S236 VanDerWaalsContact O-OG 3.1Å; L232-I293 WeakPolarHBondContact CD2-O 3.34Å; L232-Y294 HydrophobicContact CB-CD2 4.15Å; L232-Y294 HydrophobicContact CD2-CD2 4.01Å; L232-L392 HydrophobicContact CB-CD2 3.96Å; L232-L392 HydrophobicContact CD2-CD1 4.28Å; L232-L392 HydrophobicContact CD2-CD2 3.93Å; L232-L392 HydrophobicContact CD2-CG 4.45Å; L232-L392 HydrophobicContact CG-CD1 4.2Å; L232-L392 HydrophobicContact CG-CD2 3.96Å
233	I	93.3	Very high	91.4	Very high	12 Å²	12	34.4 Å²	34.4	6%	0.062	18%	0.178	C	C	.	.	H	α-helix	trans	-62.5	-42.8	175.5	-65.9	162.2	0	0	0	111.2	P93 L96 C97 Q229 A230 Y231 S236 A237 Y294	P93-I233 HydrophobicContact CB-CD1 3.64Å; P93-I233 HydrophobicContact CB-CG1 4.09Å; L96-I233 HydrophobicContact CD2-CD1 4.46Å; L96-I233 HydrophobicContact CD2-CG2 3.72Å; C97-I233 HydrophobicContact CB-CG2 3.73Å; Q229-I233 VanDerWaalsContact O-CG1 3.27Å; Q229-I233 WeakPolarHBondContact O-CG1 3.47Å; Q229-I233 PolarHBondContact O-N 3.43Å; A230-I233 PolarHBondContact O-N 3.16Å; Y231-I233 VanDerWaalsContact C-N 3.34Å; Y231-I233 PolarHBondContact O-N 3.23Å; I233-S236 WeakPolarHBondContact CA-OG 3.29Å; I233-S236 PolarHBondContact O-N 3.32Å; I233-S236 PolarHBondContact O-OG 2.79Å; I233-A237 WeakPolarHBondContact O-CB 3.4Å; I233-A237 PolarHBondContact O-N 2.96Å; I233-Y294 HydrophobicContact CG1-CE2 4.46Å
234	M	94	Very high	92	Very high	50 Å²	50	33.8 Å²	33.8	25%	0.246	17%	0.171	C	C	.	.	H	α-helix	trans	-65.3	-39.9	177.2	-73	-58.5	-61.8	0	0	112.3	V100 F211 A230 Y231 A237 L238	V100-M234 HydrophobicContact CG1-SD 4.36Å; F211-M234 HydrophobicContact CZ-CB 4.42Å; A230-M234 WeakPolarHBondContact O-CG 3.32Å; A230-M234 PolarHBondContact O-N 2.88Å; Y231-M234 PolarHBondContact O-N 3.08Å; M234-A237 PolarHBondContact O-N 2.99Å; M234-L238 WeakPolarHBondContact O-CB 3.39Å; M234-L238 WeakPolarHBondContact O-CG 3.41Å; M234-L238 PolarHBondContact O-N 3.39Å
235	I	93	Very high	92	Very high	22 Å²	22	30.3 Å²	30.3	11%	0.113	15%	0.147	C	C	.	.	H	α-helix	trans	-63.3	-45.2	175.6	-74.9	-177.2	0	0	0	110.9	L179 L180 I219 Y231 L232 A237 L238 M239	L179-I235 HydrophobicContact CD1-CG2 3.77Å; L179-I235 HydrophobicContact CD2-CB 4.16Å; L179-I235 HydrophobicContact CD2-CG1 3.91Å; L179-I235 HydrophobicContact CD2-CG2 3.87Å; L179-I235 HydrophobicContact CG-CG2 4.49Å; L180-I235 HydrophobicContact CD1-CD1 4.13Å; L180-I235 HydrophobicContact CD2-CD1 3.89Å; L180-I235 HydrophobicContact CD2-CG1 3.64Å; L180-I235 HydrophobicContact CG-CD1 3.84Å; L180-I235 HydrophobicContact CG-CG1 4.06Å; I219-I235 HydrophobicContact CD1-CD1 3.27Å; Y231-I235 WeakPolarHBondContact O-CB 3.24Å; Y231-I235 VanDerWaalsContact O-CG1 3.32Å; Y231-I235 WeakPolarHBondContact O-CG1 3.45Å; Y231-I235 PolarHBondContact O-N 3.25Å; L232-I235 PolarHBondContact O-N 3.46Å; I235-A237 VanDerWaalsContact C-N 3.32Å; I235-A237 PolarHBondContact O-N 2.81Å; I235-L238 PolarHBondContact O-N 3.42Å; I235-M239 WeakPolarHBondContact O-CB 3.19Å; I235-M239 WeakPolarHBondContact O-CG 3.19Å; I235-M239 PolarHBondContact O-N 3.47Å
236	S	93.7	Very high	92.2	Very high	1 Å²	1	30 Å²	30	1%	0.007	14%	0.143	C	C	.	.	H	α-helix	trans	-64.3	-39.1	177.1	50.1	0	0	0	0	111.9	C97 L232 I233 M239 A240	C97-S236 PolarHBondContact SG-OG 2.97Å; L232-S236 PolarHBondContact O-N 3.41Å; L232-S236 PolarHBondContact O-OG 2.93Å; L232-S236 VanDerWaalsContact O-OG 3.1Å; I233-S236 WeakPolarHBondContact CA-OG 3.29Å; I233-S236 PolarHBondContact O-N 3.32Å; I233-S236 PolarHBondContact O-OG 2.79Å; S236-M239 PolarHBondContact O-N 2.89Å; S236-A240 WeakPolarHBondContact O-CB 3.37Å; S236-A240 PolarHBondContact O-N 3.41Å
237	A	95.6	Very high	92.1	Very high	2 Å²	2	21.4 Å²	21.4	2%	0.017	11%	0.11	C	C	.	.	H	α-helix	trans	-64	-46.5	175.3	0	0	0	0	0	112	V100 V101 I233 M234 I235 M239 A240 L241	V100-A237 HydrophobicContact CB-CB 4.47Å; V100-A237 HydrophobicContact CG1-CB 3.91Å; V101-A237 HydrophobicContact CG2-CB 3.66Å; I233-A237 WeakPolarHBondContact O-CB 3.4Å; I233-A237 PolarHBondContact O-N 2.96Å; M234-A237 PolarHBondContact O-N 2.99Å; I235-A237 VanDerWaalsContact C-N 3.32Å; I235-A237 PolarHBondContact O-N 2.81Å; A237-M239 VanDerWaalsContact C-N 3.35Å; A237-M239 PolarHBondContact O-N 3Å; A237-A240 PolarHBondContact O-N 3.38Å; A237-L241 WeakPolarHBondContact O-CB 3.28Å; A237-L241 VanDerWaalsContact O-CG 3.28Å; A237-L241 WeakPolarHBondContact O-CG 3.49Å; A237-L241 PolarHBondContact O-N 2.81Å
238	L	94.6	Very high	92	Very high	4 Å²	4	19.5 Å²	19.5	2%	0.021	10%	0.102	C	C	.	.	H	α-helix	trans	-61.1	-43	176.9	-74.6	166.2	0	0	0	111.5	L179 S184 Y187 M234 I235 L241 V242	L179-L238 HydrophobicContact CD2-CB 4.25Å; L179-L238 HydrophobicContact CD2-CD1 4.36Å; S184-L238 WeakPolarHBondContact OG-CD1 3.45Å; Y187-L238 HydrophobicContact CD2-CD2 4.28Å; Y187-L238 HydrophobicContact CG-CD2 3.98Å; M234-L238 WeakPolarHBondContact O-CB 3.39Å; M234-L238 WeakPolarHBondContact O-CG 3.41Å; M234-L238 PolarHBondContact O-N 3.39Å; I235-L238 PolarHBondContact O-N 3.42Å; L238-L241 PolarHBondContact O-N 2.96Å; L238-V242 VanDerWaalsContact O-CG2 3.28Å; L238-V242 WeakPolarHBondContact O-CG2 3.45Å; L238-V242 PolarHBondContact O-N 3.44Å
239	M	93.1	Very high	91.8	Very high	40 Å²	40	21.1 Å²	21.1	20%	0.197	11%	0.11	C	C	.	.	H	α-helix	trans	-64.6	-41.2	176	-76.1	-58.9	-60.6	0	0	112.9	L179 I235 S236 A237 L241 V242 F243 I396	L179-M239 HydrophobicContact CD1-CG 3.46Å; L179-M239 VanDerWaalsContact CD1-CG 3.46Å; L179-M239 HydrophobicContact CD1-SD 3.39Å; L179-M239 WeakPolarHBondContact CD1-SD 3.5Å; L179-M239 HydrophobicContact CG-CG 4.16Å; L179-M239 HydrophobicContact CG-SD 3.87Å; I235-M239 WeakPolarHBondContact O-CB 3.19Å; I235-M239 WeakPolarHBondContact O-CG 3.19Å; I235-M239 PolarHBondContact O-N 3.47Å; S236-M239 PolarHBondContact O-N 2.89Å; A237-M239 VanDerWaalsContact C-N 3.35Å; A237-M239 PolarHBondContact O-N 3Å; M239-L241 VanDerWaalsContact C-N 3.33Å; M239-L241 PolarHBondContact O-N 3.45Å; M239-V242 WeakPolarHBondContact O-CB 3.32Å; M239-V242 PolarHBondContact O-N 3.33Å; M239-F243 HydrophobicContact CE-CE1 4.46Å; M239-F243 HydrophobicContact CE-CZ 4.26Å; M239-F243 PolarHBondContact O-N 3.33Å; M239-I396 HydrophobicContact CB-CD1 3.89Å; M239-I396 HydrophobicContact CB-CG1 3.98Å; M239-I396 HydrophobicContact CB-CG2 4.13Å; M239-I396 HydrophobicContact CG-CD1 4.32Å
240	A	94.9	Very high	91.8	Very high	0 Å²	0	26.3 Å²	26.3	0%	0	13%	0.129	C	C	.	.	H	α-helix	trans	-62.1	-42.5	174.5	0	0	0	0	0	111.3	V101 S236 A237 V242 F243 I244 I396 M400	V101-A240 HydrophobicContact CG2-CB 4.15Å; S236-A240 WeakPolarHBondContact O-CB 3.37Å; S236-A240 PolarHBondContact O-N 3.41Å; A237-A240 PolarHBondContact O-N 3.38Å; A240-V242 PolarHBondContact O-N 3.47Å; A240-F243 PolarHBondContact O-N 3.33Å; A240-I244 WeakPolarHBondContact O-CD1 3.47Å; A240-I244 VanDerWaalsContact O-CG1 3.24Å; A240-I244 WeakPolarHBondContact O-CG1 3.36Å; A240-I244 PolarHBondContact O-N 2.88Å; A240-I396 HydrophobicContact CB-CG2 4.45Å; A240-M400 HydrophobicContact CB-CB 4.44Å
241	L	93.6	Very high	91.8	Very high	3 Å²	3	24.1 Å²	24.1	2%	0.016	11%	0.111	C	C	.	.	H	α-helix	trans	-63	-39.8	176	-72.4	169.7	0	0	0	112.6	V101 T104 I105 Y111 Y187 A237 L238 M239 I244 K245	V101-L241 HydrophobicContact CG1-CD2 4.11Å; V101-L241 HydrophobicContact CG2-CG 4.39Å; T104-L241 HydrophobicContact CG2-CD1 3.74Å; T104-L241 HydrophobicContact CG2-CD2 3.71Å; T104-L241 HydrophobicContact CG2-CG 4.4Å; I105-L241 HydrophobicContact CD1-CD2 3.66Å; I105-L241 HydrophobicContact CG1-CD2 4.09Å; Y111-L241 HydrophobicContact CD1-CB 3.99Å; Y111-L241 HydrophobicContact CD1-CD2 4.1Å; Y111-L241 HydrophobicContact CD2-CD2 4.44Å; Y111-L241 HydrophobicContact CE1-CB 3.68Å; Y111-L241 HydrophobicContact CE1-CD2 4.37Å; Y111-L241 HydrophobicContact CE1-CG 4.43Å; Y111-L241 HydrophobicContact CG-CD2 4.17Å; Y187-L241 HydrophobicContact CD2-CD1 4.18Å; Y187-L241 HydrophobicContact CE2-CD1 4.16Å; A237-L241 WeakPolarHBondContact O-CB 3.28Å; A237-L241 VanDerWaalsContact O-CG 3.28Å; A237-L241 WeakPolarHBondContact O-CG 3.49Å; A237-L241 PolarHBondContact O-N 2.81Å; L238-L241 PolarHBondContact O-N 2.96Å; M239-L241 VanDerWaalsContact C-N 3.33Å; M239-L241 PolarHBondContact O-N 3.45Å; L241-I244 PolarHBondContact O-N 3.36Å; L241-K245 WeakPolarHBondContact O-CB 3.26Å; L241-K245 PolarHBondContact O-N 3.39Å
242	V	91.9	Very high	91.7	Very high	17 Å²	17	23.1 Å²	23.1	10%	0.103	11%	0.107	C	C	.	.	H	α-helix	trans	-59.3	-47.8	172.4	167.7	0	0	0	0	110.1	F183 L238 M239 A240 I244 K245 Y246	F183-V242 HydrophobicContact CD1-CG2 3.42Å; F183-V242 VanDerWaalsContact CD1-CG2 3.42Å; F183-V242 HydrophobicContact CD2-CG2 4.1Å; F183-V242 HydrophobicContact CE1-CG1 4.24Å; F183-V242 HydrophobicContact CE1-CG2 3.43Å; F183-V242 VanDerWaalsContact CE1-CG2 3.43Å; F183-V242 HydrophobicContact CE2-CG2 4.14Å; F183-V242 HydrophobicContact CG-CG2 3.79Å; F183-V242 HydrophobicContact CZ-CG1 4.13Å; F183-V242 HydrophobicContact CZ-CG2 3.82Å; L238-V242 VanDerWaalsContact O-CG2 3.28Å; L238-V242 WeakPolarHBondContact O-CG2 3.45Å; L238-V242 PolarHBondContact O-N 3.44Å; M239-V242 WeakPolarHBondContact O-CB 3.32Å; M239-V242 PolarHBondContact O-N 3.33Å; A240-V242 PolarHBondContact O-N 3.47Å; V242-I244 PolarHBondContact O-N 2.93Å; V242-K245 PolarHBondContact O-N 3.49Å; V242-Y246 HydrophobicContact CB-CD2 4.46Å; V242-Y246 HydrophobicContact CG1-CD2 3.72Å; V242-Y246 HydrophobicContact CG1-CE2 3.96Å; V242-Y246 WeakPolarHBondContact O-CD2 3.24Å; V242-Y246 PolarHBondContact O-N 2.85Å; V242-Y246 VanDerWaalsContact O-N 3.11Å
243	F	91.9	Very high	91.8	Very high	35 Å²	35	24.1 Å²	24.1	15%	0.154	11%	0.11	C	C	.	.	H	α-helix	trans	-62.9	-41.6	176.1	-73.2	-22	0	0	0	113	M145 M239 A240 K245 L247 I396 F397 M400	M145-F243 HydrophobicContact CE-CE1 4.08Å; M145-F243 HydrophobicContact CE-CZ 4.35Å; M239-F243 HydrophobicContact CE-CE1 4.46Å; M239-F243 HydrophobicContact CE-CZ 4.26Å; M239-F243 PolarHBondContact O-N 3.33Å; A240-F243 PolarHBondContact O-N 3.33Å; F243-K245 PolarHBondContact O-N 3.34Å; F243-L247 HydrophobicContact CB-CD1 3.92Å; F243-L247 HydrophobicContact CD1-CD1 4.19Å; F243-L247 HydrophobicContact CG-CD1 4.16Å; F243-L247 WeakPolarHBondContact O-CB 3.39Å; F243-L247 WeakPolarHBondContact O-CG 3.36Å; F243-L247 PolarHBondContact O-N 3.36Å; F243-I396 HydrophobicContact CD2-CG2 3.75Å; F243-I396 HydrophobicContact CE2-CG2 3.7Å; F243-F397 HydrophobicContact CE2-CE1 4.39Å; F243-M400 HydrophobicContact CB-CE 4.29Å; F243-M400 HydrophobicContact CB-CG 4.22Å; F243-M400 HydrophobicContact CB-SD 3.71Å; F243-M400 HydrophobicContact CD2-SD 3.83Å; F243-M400 HydrophobicContact CG-SD 4.13Å
244	I	91.6	Very high	91.8	Very high	4 Å²	4	25.7 Å²	25.7	2%	0.021	12%	0.119	C	C	.	.	H	α-helix	trans	-62.3	-43.7	178	-68.4	159	0	0	0	111.1	V101 I105 A240 L241 V242 M400 K404	V101-I244 HydrophobicContact CG1-CD1 3.65Å; I105-I244 HydrophobicContact CD1-CB 4.37Å; I105-I244 HydrophobicContact CD1-CD1 4.11Å; I105-I244 HydrophobicContact CD1-CG2 3.65Å; I105-I244 HydrophobicContact CG1-CD1 4.24Å; A240-I244 WeakPolarHBondContact O-CD1 3.47Å; A240-I244 VanDerWaalsContact O-CG1 3.24Å; A240-I244 WeakPolarHBondContact O-CG1 3.36Å; A240-I244 PolarHBondContact O-N 2.88Å; L241-I244 PolarHBondContact O-N 3.36Å; V242-I244 PolarHBondContact O-N 2.93Å; I244-M400 HydrophobicContact CG1-CG 4.42Å; I244-K404 HydrophobicContact CG1-CD 4.44Å; I244-K404 HydrophobicContact CG1-CG 4.19Å; I244-K404 HydrophobicContact CG2-CD 4.25Å; I244-K404 PolarHBondContact O-NZ 2.93Å
245	K	90.1	Very high	91.7	Very high	10 Å²	10	23.4 Å²	23.4	4%	0.043	11%	0.107	C	C	.	.	H	α-helix	trans	-67.2	-40.7	-177.3	-179.8	66.9	-168.2	86	0	113.5	F110 Y111 K113 L241 V242 F243	F110-K245 HydrophobicContact CD1-CD 3.98Å; F110-K245 HydrophobicContact CE1-CD 3.77Å; F110-K245 HydrophobicContact CE1-CG 4.22Å; F110-K245 HydrophobicContact CZ-CD 4.26Å; F110-K245 WeakPolarHBondContact O-CD 3.48Å; F110-K245 WeakPolarHBondContact O-CE 3.44Å; Y111-K245 HydrophobicContact CD1-CB 3.98Å; Y111-K245 HydrophobicContact CD1-CD 4.48Å; K113-K245 PolarHBondContact O-NZ 3.33Å; L241-K245 WeakPolarHBondContact O-CB 3.26Å; L241-K245 PolarHBondContact O-N 3.39Å; V242-K245 PolarHBondContact O-N 3.49Å; F243-K245 PolarHBondContact O-N 3.34Å
246	Y	88.3	Confident	91.7	Very high	49 Å²	49	22.4 Å²	22.4	19%	0.192	10%	0.103	C	C	.	.	H	α-helix	trans	-105.6	-16.7	-167.3	-65.6	-61.9	0	0	0	114.5	L119 V242	L119-Y246 HydrophobicContact CD1-CG 4.38Å; L119-Y246 HydrophobicContact CD2-CD2 4.46Å; L119-Y246 HydrophobicContact CD2-CG 4.31Å; L119-Y246 HydrophobicContact CG-CG 4.14Å; V242-Y246 HydrophobicContact CB-CD2 4.46Å; V242-Y246 HydrophobicContact CG1-CD2 3.72Å; V242-Y246 HydrophobicContact CG1-CE2 3.96Å; V242-Y246 WeakPolarHBondContact O-CD2 3.24Å; V242-Y246 PolarHBondContact O-N 2.85Å; V242-Y246 VanDerWaalsContact O-N 3.11Å
247	L	87.5	Confident	91.6	Very high	4 Å²	4	24.2 Å²	24.2	2%	0.021	12%	0.118	C	C	.	.	S	Bend	trans	-89.6	127.5	176.5	-64.6	174	0	0	0	110.8	L119 T122 M145 F243 A252 I255 M400 K404	L119-L247 HydrophobicContact CD1-CD2 4.3Å; T122-L247 HydrophobicContact CG2-CD2 4.14Å; M145-L247 HydrophobicContact CE-CD1 4.4Å; M145-L247 HydrophobicContact CE-CD2 4.5Å; F243-L247 HydrophobicContact CB-CD1 3.92Å; F243-L247 HydrophobicContact CD1-CD1 4.19Å; F243-L247 HydrophobicContact CG-CD1 4.16Å; F243-L247 WeakPolarHBondContact O-CB 3.39Å; F243-L247 WeakPolarHBondContact O-CG 3.36Å; F243-L247 PolarHBondContact O-N 3.36Å; L247-A252 HydrophobicContact CB-CB 4.08Å; L247-I255 HydrophobicContact CD1-CD1 4.03Å; L247-I255 HydrophobicContact CD2-CD1 3.92Å; L247-M400 HydrophobicContact CD1-CE 3.46Å; L247-M400 VanDerWaalsContact CD1-CE 3.46Å; L247-M400 HydrophobicContact CD1-SD 4.39Å; L247-K404 PolarHBondContact O-NZ 2.59Å
248	P	88.2	Confident	91.5	Very high	29 Å²	29	26.8 Å²	26.8	19%	0.188	13%	0.133	C	C	.	.			trans	-56.8	158.6	167.3	-24.1	35	0	0	0	112.1	E126 A252	E126-P248 HydrophobicContact CB-CB 4.5Å; E126-P248 HydrophobicContact CG-CB 3.92Å; E126-P248 WeakPolarHBondContact OE1-CB 3.36Å; E126-P248 WeakPolarHBondContact OE2-CB 3.41Å; P248-A252 WeakPolarHBondContact O-CB 3.27Å; P248-A252 PolarHBondContact O-N 3.27Å
249	E	86.7	Confident	91.2	Very high	79 Å²	79	27.3 Å²	27.3	37%	0.369	14%	0.135	S	C	.	.	H	α-helix	trans	-62.7	-53.4	-172.8	-67.9	173.3	-167.3	0	0	112.7	T251 A252 W253 T408	E249-T251 PolarHBondContact O-N 3.22Å; E249-A252 PolarHBondContact O-N 2.77Å; E249-W253 PolarHBondContact O-N 3.49Å; E249-T408 HydrophobicContact CG-CG2 4.2Å
250	W	89.8	Confident	91.1	Very high	120 Å²	120	25.9 Å²	25.9	46%	0.455	13%	0.129	S	C	.	.	H	α-helix	trans	-66.2	-44.5	-177.1	-75	75.4	0	0	0	110.9	E126 R134 A252 W253 L254	E126-W250 PolarHBondContact OE2-N 3.45Å; E126-W250 VanDerWaalsContact OE2-N 3.14Å; R134-W250 HydrophobicContact CG-CG 4.47Å; W250-A252 VanDerWaalsContact C-N 3.29Å; W250-A252 PolarHBondContact O-N 2.96Å; W250-W253 PolarHBondContact O-N 3.35Å; W250-L254 WeakPolarHBondContact O-CB 3.34Å; W250-L254 PolarHBondContact O-N 2.95Å
251	T	91.9	Very high	90.8	Very high	0 Å²	0	29.7 Å²	29.7	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-56.1	-42.4	174.7	-64.9	0	0	0	0	111.4	T122 E126 N141 A142 E249 L254 I255	T122-T251 HydrophobicContact CG2-CG2 4.34Å; E126-T251 VanDerWaalsContact OE1-CB 3.26Å; E126-T251 WeakPolarHBondContact OE1-CB 3.46Å; E126-T251 PolarHBondContact OE1-N 3.19Å; E126-T251 PolarHBondContact OE1-OG1 3.33Å; N141-T251 HydrophobicContact CB-CG2 3.97Å; A142-T251 HydrophobicContact CB-CG2 4.41Å; E249-T251 PolarHBondContact O-N 3.22Å; T251-L254 PolarHBondContact O-N 3.48Å; T251-I255 HydrophobicContact CG2-CD1 3.52Å; T251-I255 HydrophobicContact CG2-CG1 4.25Å; T251-I255 WeakPolarHBondContact O-CB 3.25Å; T251-I255 WeakPolarHBondContact O-CD1 3.47Å; T251-I255 WeakPolarHBondContact O-CG1 3.49Å; T251-I255 PolarHBondContact O-N 3.27Å
252	A	91.6	Very high	90.5	Very high	0 Å²	0	32 Å²	32	0%	0	16%	0.161	C	C	.	.	H	α-helix	trans	-64.1	-46.7	179.9	0	0	0	0	0	112.9	L247 P248 E249 W250 L254 I255 L256 M400 K404	L247-A252 HydrophobicContact CB-CB 4.08Å; P248-A252 WeakPolarHBondContact O-CB 3.27Å; P248-A252 PolarHBondContact O-N 3.27Å; E249-A252 PolarHBondContact O-N 2.77Å; W250-A252 VanDerWaalsContact C-N 3.29Å; W250-A252 PolarHBondContact O-N 2.96Å; A252-L254 VanDerWaalsContact C-N 3.3Å; A252-L254 PolarHBondContact O-N 3.18Å; A252-I255 PolarHBondContact O-N 2.85Å; A252-L256 WeakPolarHBondContact O-CG 3.32Å; A252-L256 PolarHBondContact O-N 2.91Å; A252-M400 HydrophobicContact CB-CE 3.65Å; A252-K404 HydrophobicContact CB-CD 4.46Å; A252-K404 VanDerWaalsContact CB-CE 3.42Å; A252-K404 HydrophobicContact CB-CG 4.42Å
253	W	92.9	Very high	90.2	Very high	25 Å²	25	32.4 Å²	32.4	10%	0.095	16%	0.163	C	C	.	.	H	α-helix	trans	-62.1	-40.5	177	-63.5	120.4	0	0	0	111.8	E249 W250 L256 A257 L401 K404 L452 Y455 F456	E249-W253 PolarHBondContact O-N 3.49Å; W250-W253 PolarHBondContact O-N 3.35Å; W253-L256 HydrophobicContact CE3-CD1 4.1Å; W253-L256 HydrophobicContact CZ3-CD1 4.3Å; W253-L256 PolarHBondContact O-N 2.93Å; W253-A257 PolarHBondContact O-N 3.17Å; W253-L401 HydrophobicContact CZ3-CG 4.21Å; W253-K404 HydrophobicContact CH2-CB 4Å; W253-K404 HydrophobicContact CZ2-CB 4.02Å; W253-L452 HydrophobicContact CE3-CD2 3.42Å; W253-L452 VanDerWaalsContact CE3-CD2 3.42Å; W253-L452 HydrophobicContact CZ3-CD2 3.81Å; W253-Y455 HydrophobicContact CD2-CE1 4.37Å; W253-Y455 AromaticContact CE2-CE1 3.69Å; W253-Y455 AromaticContact CE2-CZ 3.94Å; W253-Y455 HydrophobicContact CE3-CD1 4.43Å; W253-Y455 AromaticContact CH2-CD1 3.65Å; W253-Y455 HydrophobicContact CH2-CD1 3.65Å; W253-Y455 AromaticContact CH2-CD2 3.61Å; W253-Y455 HydrophobicContact CH2-CD2 3.61Å; W253-Y455 AromaticContact CH2-CE1 3.65Å; W253-Y455 HydrophobicContact CH2-CE1 3.65Å; W253-Y455 AromaticContact CH2-CE2 3.6Å; W253-Y455 HydrophobicContact CH2-CE2 3.6Å; W253-Y455 AromaticContact CH2-CG 3.64Å; W253-Y455 HydrophobicContact CH2-CG 3.64Å; W253-Y455 AromaticContact CH2-CZ 3.62Å; W253-Y455 AromaticContact CZ2-CD1 3.84Å; W253-Y455 HydrophobicContact CZ2-CD1 3.84Å; W253-Y455 HydrophobicContact CZ2-CD2 4.1Å; W253-Y455 AromaticContact CZ2-CE1 3.32Å; W253-Y455 HydrophobicContact CZ2-CE1 3.32Å; W253-Y455 AromaticContact CZ2-CE2 3.61Å; W253-Y455 HydrophobicContact CZ2-CE2 3.61Å; W253-Y455 HydrophobicContact CZ2-CG 4.2Å; W253-Y455 AromaticContact CZ2-CZ 3.19Å; W253-Y455 WeakPolarHBondContact CZ2-OH 3.3Å; W253-Y455 AromaticContact CZ3-CD1 3.97Å; W253-Y455 HydrophobicContact CZ3-CD1 3.97Å; W253-Y455 HydrophobicContact CZ3-CD2 4.41Å; W253-Y455 HydrophobicContact CZ3-CE1 4.29Å; W253-Y455 HydrophobicContact CZ3-CG 4.04Å; W253-F456 HydrophobicContact CD2-CZ 4.49Å; W253-F456 HydrophobicContact CG-CZ 4.33Å
254	L	93.1	Very high	89.7	Confident	46 Å²	46	34 Å²	34	24%	0.241	17%	0.173	C	C	.	.	H	α-helix	trans	-65.9	-43.9	177.8	-152.6	176.7	0	0	0	111.3	I139 A142 W250 T251 A252 L256 A257 V258	I139-L254 HydrophobicContact CB-CD1 4.16Å; I139-L254 HydrophobicContact CG1-CD1 3.6Å; A142-L254 HydrophobicContact CB-CB 4.17Å; A142-L254 HydrophobicContact CB-CD1 3.94Å; A142-L254 HydrophobicContact CB-CD2 3.82Å; A142-L254 HydrophobicContact CB-CG 4.2Å; W250-L254 WeakPolarHBondContact O-CB 3.34Å; W250-L254 PolarHBondContact O-N 2.95Å; T251-L254 PolarHBondContact O-N 3.48Å; A252-L254 VanDerWaalsContact C-N 3.3Å; A252-L254 PolarHBondContact O-N 3.18Å; L254-L256 PolarHBondContact O-N 2.84Å; L254-A257 PolarHBondContact O-N 2.98Å; L254-V258 HydrophobicContact CD2-CG2 3.47Å; L254-V258 VanDerWaalsContact CD2-CG2 3.47Å; L254-V258 WeakPolarHBondContact O-CG2 3.18Å; L254-V258 PolarHBondContact O-N 3.28Å
255	I	92.5	Very high	89.3	Confident	1 Å²	1	38.4 Å²	38.4	1%	0.005	20%	0.196	C	C	.	.	H	α-helix	trans	-59.4	-45.6	175.7	-73.4	164.2	0	0	0	110.8	A142 M145 L247 T251 A252 A257 V258 I259	A142-I255 HydrophobicContact CB-CG1 3.98Å; M145-I255 HydrophobicContact CB-CD1 4.33Å; M145-I255 HydrophobicContact CE-CD1 4.11Å; M145-I255 HydrophobicContact CE-CG2 4.43Å; M145-I255 HydrophobicContact CG-CD1 4.09Å; M145-I255 HydrophobicContact SD-CD1 3.55Å; M145-I255 VanDerWaalsContact SD-CD1 3.55Å; M145-I255 HydrophobicContact SD-CG1 4.01Å; M145-I255 HydrophobicContact SD-CG2 4.07Å; L247-I255 HydrophobicContact CD1-CD1 4.03Å; L247-I255 HydrophobicContact CD2-CD1 3.92Å; T251-I255 HydrophobicContact CG2-CD1 3.52Å; T251-I255 HydrophobicContact CG2-CG1 4.25Å; T251-I255 WeakPolarHBondContact O-CB 3.25Å; T251-I255 WeakPolarHBondContact O-CD1 3.47Å; T251-I255 WeakPolarHBondContact O-CG1 3.49Å; T251-I255 PolarHBondContact O-N 3.27Å; A252-I255 PolarHBondContact O-N 2.85Å; I255-A257 VanDerWaalsContact C-N 3.32Å; I255-A257 PolarHBondContact O-N 3.3Å; I255-V258 PolarHBondContact O-N 2.93Å; I255-I259 HydrophobicContact CG2-CD1 3.46Å; I255-I259 VanDerWaalsContact CG2-CD1 3.46Å; I255-I259 HydrophobicContact CG2-CG1 4.1Å; I255-I259 VanDerWaalsContact O-CB 3.29Å; I255-I259 WeakPolarHBondContact O-CB 3.26Å; I255-I259 VanDerWaalsContact O-CG1 3.32Å; I255-I259 WeakPolarHBondContact O-CG1 3.33Å; I255-I259 PolarHBondContact O-N 2.93Å
256	L	92.7	Very high	88.7	Confident	2 Å²	2	38.1 Å²	38.1	1%	0.01	20%	0.195	C	C	.	.	H	α-helix	trans	-60	-42.9	177	-71.3	170.4	0	0	0	111.7	A252 W253 L254 S260 F397 M400 L401 I448	A252-L256 WeakPolarHBondContact O-CG 3.32Å; A252-L256 PolarHBondContact O-N 2.91Å; W253-L256 HydrophobicContact CE3-CD1 4.1Å; W253-L256 HydrophobicContact CZ3-CD1 4.3Å; W253-L256 PolarHBondContact O-N 2.93Å; L254-L256 PolarHBondContact O-N 2.84Å; L256-S260 WeakPolarHBondContact O-CB 3.43Å; L256-S260 PolarHBondContact O-N 3.13Å; L256-S260 VanDerWaalsContact O-N 3.16Å; L256-S260 PolarHBondContact O-OG 3.1Å; L256-F397 HydrophobicContact CD2-CB 4.13Å; L256-F397 HydrophobicContact CD2-CD1 3.86Å; L256-F397 HydrophobicContact CD2-CG 4.44Å; L256-M400 HydrophobicContact CD2-CG 4.5Å; L256-M400 HydrophobicContact CD2-SD 4.09Å; L256-M400 HydrophobicContact CG-CE 4.3Å; L256-M400 HydrophobicContact CG-SD 4.47Å; L256-L401 HydrophobicContact CD1-CB 3.97Å; L256-L401 HydrophobicContact CD1-CG 4.16Å; L256-I448 HydrophobicContact CB-CG2 4.26Å; L256-I448 HydrophobicContact CD2-CD1 4.38Å
257	A	92.1	Very high	88.1	Confident	39 Å²	39	37.7 Å²	37.7	32%	0.322	20%	0.198	S	C	.	.	H	α-helix	trans	-66.4	-41.9	178.1	0	0	0	0	0	112.4	W253 L254 I255 S260 V261 L452	W253-A257 PolarHBondContact O-N 3.17Å; L254-A257 PolarHBondContact O-N 2.98Å; I255-A257 VanDerWaalsContact C-N 3.32Å; I255-A257 PolarHBondContact O-N 3.3Å; A257-S260 PolarHBondContact O-OG 2.9Å; A257-V261 WeakPolarHBondContact O-CG2 3.37Å; A257-V261 PolarHBondContact O-N 3.37Å; A257-L452 HydrophobicContact CB-CD1 4.08Å
258	V	91.9	Very high	87.5	Confident	55 Å²	55	42.3 Å²	42.3	33%	0.333	22%	0.222	S	C	.	.	H	α-helix	trans	-79.9	-35.5	-177.5	179	0	0	0	0	112.1	I146 L254 I255 S260 V261 Y262	I146-V258 HydrophobicContact CD1-CB 3.59Å; I146-V258 HydrophobicContact CD1-CG1 3.48Å; I146-V258 VanDerWaalsContact CD1-CG1 3.48Å; I146-V258 HydrophobicContact CD1-CG2 4.21Å; I146-V258 HydrophobicContact CG1-CG1 4.43Å; L254-V258 HydrophobicContact CD2-CG2 3.47Å; L254-V258 VanDerWaalsContact CD2-CG2 3.47Å; L254-V258 WeakPolarHBondContact O-CG2 3.18Å; L254-V258 PolarHBondContact O-N 3.28Å; I255-V258 PolarHBondContact O-N 2.93Å; V258-S260 VanDerWaalsContact C-N 3.32Å; V258-S260 PolarHBondContact O-N 2.98Å; V258-V261 PolarHBondContact O-N 3.48Å; V258-Y262 VanDerWaalsContact O-CB 3.31Å; V258-Y262 WeakPolarHBondContact O-CB 3.3Å; V258-Y262 PolarHBondContact O-N 3.22Å
259	I	89.3	Confident	86.8	Confident	15 Å²	15	43.6 Å²	43.6	8%	0.077	23%	0.231	C	C	.	.	H	α-helix	trans	-65	-38.1	175.6	-71.8	-179.6	0	0	0	110.9	I149 I255 Y262 D263 F397 L444	I149-I259 HydrophobicContact CD1-CD1 3.96Å; I255-I259 HydrophobicContact CG2-CD1 3.46Å; I255-I259 VanDerWaalsContact CG2-CD1 3.46Å; I255-I259 HydrophobicContact CG2-CG1 4.1Å; I255-I259 VanDerWaalsContact O-CB 3.29Å; I255-I259 WeakPolarHBondContact O-CB 3.26Å; I255-I259 VanDerWaalsContact O-CG1 3.32Å; I255-I259 WeakPolarHBondContact O-CG1 3.33Å; I255-I259 PolarHBondContact O-N 2.93Å; I259-Y262 PolarHBondContact O-N 3.18Å; I259-D263 WeakPolarHBondContact O-CB 3.29Å; I259-D263 PolarHBondContact O-N 3.38Å; I259-F397 HydrophobicContact CD1-CE1 3.57Å; I259-F397 HydrophobicContact CD1-CZ 3.57Å; I259-F397 HydrophobicContact CG2-CD2 4.37Å; I259-F397 HydrophobicContact CG2-CE1 4.25Å; I259-F397 HydrophobicContact CG2-CE2 3.86Å; I259-F397 HydrophobicContact CG2-CZ 3.81Å; I259-L444 HydrophobicContact CG2-CD1 4.42Å
260	S	90.1	Very high	85.8	Confident	10 Å²	10	44.6 Å²	44.6	7%	0.07	25%	0.245	C	C	.	.	H	α-helix	trans	-61.2	-44.1	173.3	45.1	0	0	0	0	112.7	L256 A257 V258 L264 L444	L256-S260 WeakPolarHBondContact O-CB 3.43Å; L256-S260 PolarHBondContact O-N 3.13Å; L256-S260 VanDerWaalsContact O-N 3.16Å; L256-S260 PolarHBondContact O-OG 3.1Å; A257-S260 PolarHBondContact O-OG 2.9Å; V258-S260 VanDerWaalsContact C-N 3.32Å; V258-S260 PolarHBondContact O-N 2.98Å; S260-L264 PolarHBondContact O-N 3Å; S260-L444 VanDerWaalsContact CA-CD2 3.5Å
261	V	88.5	Confident	84.9	Confident	81 Å²	81	47.6 Å²	47.6	49%	0.491	26%	0.261	S	S	.	.	H	α-helix	trans	-65.9	-40.6	174.1	176.4	0	0	0	0	111.4	A257 V258 L264 L265	A257-V261 WeakPolarHBondContact O-CG2 3.37Å; A257-V261 PolarHBondContact O-N 3.37Å; V258-V261 PolarHBondContact O-N 3.48Å; V261-L264 WeakPolarHBondContact O-CB 3.04Å; V261-L264 PolarHBondContact O-N 3.43Å; V261-L265 HydrophobicContact CG1-CD1 4.09Å; V261-L265 HydrophobicContact CG1-CG 4.44Å; V261-L265 WeakPolarHBondContact O-CG 3.25Å; V261-L265 PolarHBondContact O-N 3Å
262	Y	87.5	Confident	83.9	Confident	50 Å²	50	47.8 Å²	47.8	20%	0.196	26%	0.263	C	S	.	.	H	α-helix	trans	-63.3	-44.2	178.9	175.2	-98.2	0	0	0	112	I150 V258 I259 L264 L265 A266	I150-Y262 HydrophobicContact CD1-CD2 4.11Å; I150-Y262 HydrophobicContact CD1-CE2 3.82Å; I150-Y262 HydrophobicContact CG1-CD2 4.33Å; I150-Y262 HydrophobicContact CG1-CE2 3.74Å; V258-Y262 VanDerWaalsContact O-CB 3.31Å; V258-Y262 WeakPolarHBondContact O-CB 3.3Å; V258-Y262 PolarHBondContact O-N 3.22Å; I259-Y262 PolarHBondContact O-N 3.18Å; Y262-L264 VanDerWaalsContact C-N 3.31Å; Y262-L264 PolarHBondContact O-N 3.42Å; Y262-L265 PolarHBondContact O-N 2.96Å; Y262-A266 HydrophobicContact CE1-CB 4.17Å; Y262-A266 VanDerWaalsContact O-CB 3.24Å; Y262-A266 WeakPolarHBondContact O-CB 3.2Å; Y262-A266 PolarHBondContact O-N 3.49Å
263	D	85.3	Confident	82.8	Confident	27 Å²	27	48.9 Å²	48.9	14%	0.144	27%	0.27	C	S	.	.	H	α-helix	trans	-61	-42	177.6	-170.9	53.9	0	0	0	111.1	I259 L265 A266 V267 P442	I259-D263 WeakPolarHBondContact O-CB 3.29Å; I259-D263 PolarHBondContact O-N 3.38Å; D263-L265 PolarHBondContact O-N 3.37Å; D263-A266 PolarHBondContact O-N 2.82Å; D263-V267 WeakPolarHBondContact O-CG2 3.31Å; D263-V267 PolarHBondContact O-N 2.96Å; D263-V267 VanDerWaalsContact O-N 3.1Å; D263-P442 WeakPolarHBondContact OD2-CB 3.48Å
264	L	82.7	Confident	81.4	Confident	69 Å²	69	50.9 Å²	50.9	36%	0.361	28%	0.282	S	S	.	.	H	α-helix	trans	-55.9	-51.1	171.8	-169.3	70.8	0	0	0	111.6	S260 V261 Y262 V267 L268 P442 P445	S260-L264 PolarHBondContact O-N 3Å; V261-L264 WeakPolarHBondContact O-CB 3.04Å; V261-L264 PolarHBondContact O-N 3.43Å; Y262-L264 VanDerWaalsContact C-N 3.31Å; Y262-L264 PolarHBondContact O-N 3.42Å; L264-V267 PolarHBondContact O-N 3.2Å; L264-L268 HydrophobicContact CD1-CD1 3.24Å; L264-L268 HydrophobicContact CG-CD1 3.52Å; L264-L268 WeakPolarHBondContact O-CB 3.44Å; L264-L268 WeakPolarHBondContact O-CD1 3.23Å; L264-L268 PolarHBondContact O-N 2.96Å; L264-P442 HydrophobicContact CD1-CG 3.83Å; L264-P445 HydrophobicContact CB-CB 4.45Å; L264-P445 HydrophobicContact CB-CG 4.3Å; L264-P445 HydrophobicContact CD1-CG 4.06Å
265	L	82.8	Confident	80.3	Confident	95 Å²	95	53.2 Å²	53.2	50%	0.497	29%	0.287	S	S	.	.	H	α-helix	trans	-66.8	-40	-179.8	-66.2	175.4	0	0	0	112.5	V261 Y262 D263 V267 C269	V261-L265 HydrophobicContact CG1-CD1 4.09Å; V261-L265 HydrophobicContact CG1-CG 4.44Å; V261-L265 WeakPolarHBondContact O-CG 3.25Å; V261-L265 PolarHBondContact O-N 3Å; Y262-L265 PolarHBondContact O-N 2.96Å; D263-L265 PolarHBondContact O-N 3.37Å; L265-V267 VanDerWaalsContact C-N 3.28Å; L265-V267 PolarHBondContact O-N 3.39Å; L265-C269 WeakPolarHBondContact O-CB 3.29Å; L265-C269 PolarHBondContact O-N 2.91Å; L265-C269 PolarHBondContact O-SG 3.33Å
266	A	78	Confident	79.2	Confident	4 Å²	4	56.3 Å²	56.3	3%	0.033	30%	0.304	C	S	.	.	H	α-helix	trans	-69.3	-25	-177.6	0	0	0	0	0	113	Y262 D263 G272 L274	Y262-A266 HydrophobicContact CE1-CB 4.17Å; Y262-A266 VanDerWaalsContact O-CB 3.24Å; Y262-A266 WeakPolarHBondContact O-CB 3.2Å; Y262-A266 PolarHBondContact O-N 3.49Å; D263-A266 PolarHBondContact O-N 2.82Å; A266-G272 WeakPolarHBondContact O-CA 3.46Å; A266-L274 HydrophobicContact CB-CB 4.48Å; A266-L274 HydrophobicContact CB-CD1 3.88Å; A266-L274 HydrophobicContact CB-CG 4.46Å
267	V	74.5	Confident	78.1	Confident	41 Å²	41	57.7 Å²	57.7	25%	0.248	31%	0.311	C	S	.	.	H	α-helix	trans	-90.7	-46.2	175.6	176.3	0	0	0	0	112	D263 L264 L265 P442	D263-V267 WeakPolarHBondContact O-CG2 3.31Å; D263-V267 PolarHBondContact O-N 2.96Å; D263-V267 VanDerWaalsContact O-N 3.1Å; L264-V267 PolarHBondContact O-N 3.2Å; L265-V267 VanDerWaalsContact C-N 3.28Å; L265-V267 PolarHBondContact O-N 3.39Å; V267-P442 HydrophobicContact CB-CB 4.42Å; V267-P442 HydrophobicContact CB-CG 4.15Å; V267-P442 HydrophobicContact CG1-CG 4.41Å; V267-P442 HydrophobicContact CG2-CB 4.13Å; V267-P442 HydrophobicContact CG2-CG 4.4Å
268	L	74.9	Confident	76.9	Confident	101 Å²	101	59.1 Å²	59.1	53%	0.529	32%	0.315	S	S	.	.	H	α-helix	trans	-74.6	-29.8	-175.9	-79.6	143.4	0	0	0	113.3	L264	L264-L268 HydrophobicContact CD1-CD1 3.24Å; L264-L268 HydrophobicContact CG-CD1 3.52Å; L264-L268 WeakPolarHBondContact O-CB 3.44Å; L264-L268 WeakPolarHBondContact O-CD1 3.23Å; L264-L268 PolarHBondContact O-N 2.96Å
269	C	73.6	Confident	75.8	Confident	56 Å²	56	59.9 Å²	59.9	38%	0.378	32%	0.315	S	S	.	.	S	Bend	trans	-75.6	133.6	-179.8	-66.3	0	0	0	0	111.8	L265 K271 G272	L265-C269 WeakPolarHBondContact O-CB 3.29Å; L265-C269 PolarHBondContact O-N 2.91Å; L265-C269 PolarHBondContact O-SG 3.33Å; C269-K271 PolarHBondContact O-N 3.42Å; C269-G272 PolarHBondContact O-N 3.16Å
270	P	65.8	Low	74.5	Confident	100 Å²	100	61.1 Å²	61.1	65%	0.649	32%	0.324	S	S	*	.	T	Hydrogen-bonded Turn	trans	-67.7	-4.9	-177.3	27.6	-35.8	0	0	0	114.8
271	K	71.1	Confident	73	Confident	183 Å²	183	61 Å²	61	80%	0.796	32%	0.323	S	S	*	.	T	Hydrogen-bonded Turn	trans	-120.7	19.8	174.2	-67.7	-165.8	169	80	0	112.6	C269	C269-K271 PolarHBondContact O-N 3.42Å
272	G	71.4	Confident	71.6	Confident	4 Å²	4	63.5 Å²	63.5	4%	0.041	33%	0.329	C	S	.	.			trans	-65.6	138.6	180	0	0	0	0	0	112.1	A266 C269 L274 R275 I276	A266-G272 WeakPolarHBondContact O-CA 3.46Å; C269-G272 PolarHBondContact O-N 3.16Å; G272-L274 VanDerWaalsContact C-N 3.3Å; G272-L274 PolarHBondContact O-N 2.68Å; G272-R275 PolarHBondContact O-N 3.34Å; G272-I276 WeakPolarHBondContact O-CG1 3.37Å; G272-I276 PolarHBondContact O-N 2.86Å
273	P	67.5	Low	70.3	Confident	22 Å²	22	68.3 Å²	68.3	14%	0.143	35%	0.354	C	S	.	.	H	α-helix	trans	-62.2	-36.7	-178	21.9	-30.9	0	0	0	112.7	L154 V157 L277	L154-P273 HydrophobicContact CD2-CB 4.04Å; L154-P273 HydrophobicContact CD2-CG 4.44Å; V157-P273 HydrophobicContact CG2-CB 4.17Å; P273-L277 PolarHBondContact O-N 2.91Å; P273-L277 VanDerWaalsContact O-N 3.09Å
274	L	65.1	Low	68.9	Low	68 Å²	68	73.3 Å²	73.3	36%	0.356	37%	0.371	S	S	.	.	H	α-helix	trans	-67.2	-44.1	175.4	-75	168.7	0	0	0	111.5	A266 G272 I276 L277 V278	A266-L274 HydrophobicContact CB-CB 4.48Å; A266-L274 HydrophobicContact CB-CD1 3.88Å; A266-L274 HydrophobicContact CB-CG 4.46Å; G272-L274 VanDerWaalsContact C-N 3.3Å; G272-L274 PolarHBondContact O-N 2.68Å; L274-I276 PolarHBondContact O-N 3.28Å; L274-L277 PolarHBondContact O-N 3.02Å; L274-V278 WeakPolarHBondContact O-CG2 3.35Å; L274-V278 PolarHBondContact O-N 3.36Å
275	R	69.2	Low	67.3	Low	94 Å²	94	77.3 Å²	77.3	36%	0.355	39%	0.392	S	S	.	.	H	α-helix	trans	-61.5	-43.5	176.2	-175.5	172.8	175.6	168	1.7	112.2	G272 L277 V278 E279	G272-R275 PolarHBondContact O-N 3.34Å; R275-L277 VanDerWaalsContact C-N 3.3Å; R275-L277 PolarHBondContact O-N 3.16Å; R275-V278 PolarHBondContact O-N 3.49Å; R275-E279 HydrophobicContact CG-CG 4.27Å; R275-E279 WeakPolarHBondContact CG-OE1 3.48Å; R275-E279 IonicContact CZ-OE1 3.17Å; R275-E279 IonicContact NE-OE1 3.26Å; R275-E279 PolarHBondContact NE-OE1 3.14Å; R275-E279 IonicContact NH2-OE1 3.64Å; R275-E279 PolarHBondContact NH2-OE1 3.3Å; R275-E279 WeakPolarHBondContact O-CB 3.49Å; R275-E279 WeakPolarHBondContact O-CG 3.46Å; R275-E279 PolarHBondContact O-N 3.46Å
276	I	69.5	Low	66.1	Low	67 Å²	67	76.1 Å²	76.1	34%	0.344	38%	0.384	S	S	.	.	H	α-helix	trans	-61	-41.3	176	-67.9	164.3	0	0	0	110.8	G272 L274 T280	G272-I276 WeakPolarHBondContact O-CG1 3.37Å; G272-I276 PolarHBondContact O-N 2.86Å; L274-I276 PolarHBondContact O-N 3.28Å; I276-T280 WeakPolarHBondContact O-CB 3.39Å; I276-T280 PolarHBondContact O-N 2.68Å; I276-T280 PolarHBondContact O-OG1 3Å
277	L	68.9	Low	65	Low	31 Å²	31	80.9 Å²	80.9	16%	0.162	42%	0.415	C	S	.	.	H	α-helix	trans	-66.8	-41	178.3	-169.5	138.6	0	0	0	111.9	L156 V157 P273 L274 R275 A281	L156-L277 HydrophobicContact CD2-CD1 3.51Å; V157-L277 HydrophobicContact CG2-CB 4.34Å; V157-L277 HydrophobicContact CG2-CD1 3.89Å; P273-L277 PolarHBondContact O-N 2.91Å; P273-L277 VanDerWaalsContact O-N 3.09Å; L274-L277 PolarHBondContact O-N 3.02Å; R275-L277 VanDerWaalsContact C-N 3.3Å; R275-L277 PolarHBondContact O-N 3.16Å; L277-A281 VanDerWaalsContact O-CB 3.24Å; L277-A281 WeakPolarHBondContact O-CB 3.4Å; L277-A281 PolarHBondContact O-N 3.17Å
278	V	66.7	Low	64.1	Low	69 Å²	69	82 Å²	82	42%	0.418	42%	0.418	S	S	.	.	H	α-helix	trans	-66.6	-49.1	176.6	173.2	0	0	0	0	111.3	L274 R275 T280 A281 Q282	L274-V278 WeakPolarHBondContact O-CG2 3.35Å; L274-V278 PolarHBondContact O-N 3.36Å; R275-V278 PolarHBondContact O-N 3.49Å; V278-T280 PolarHBondContact O-N 3.35Å; V278-A281 PolarHBondContact O-N 3.33Å; V278-Q282 HydrophobicContact CG1-CG 4.5Å; V278-Q282 WeakPolarHBondContact O-CB 3.31Å; V278-Q282 VanDerWaalsContact O-CG 3.32Å; V278-Q282 WeakPolarHBondContact O-CG 3.37Å; V278-Q282 PolarHBondContact O-N 3.46Å
279	E	69.5	Low	63.4	Low	71 Å²	71	79 Å²	79	33%	0.332	40%	0.401	S	S	.	.	H	α-helix	trans	-62.2	-44	179.2	-73.2	174.9	174.9	0	0	110.9	R275 A281 Q282 E283	R275-E279 HydrophobicContact CG-CG 4.27Å; R275-E279 WeakPolarHBondContact CG-OE1 3.48Å; R275-E279 IonicContact CZ-OE1 3.17Å; R275-E279 IonicContact NE-OE1 3.26Å; R275-E279 PolarHBondContact NE-OE1 3.14Å; R275-E279 IonicContact NH2-OE1 3.64Å; R275-E279 PolarHBondContact NH2-OE1 3.3Å; R275-E279 WeakPolarHBondContact O-CB 3.49Å; R275-E279 WeakPolarHBondContact O-CG 3.46Å; R275-E279 PolarHBondContact O-N 3.46Å; E279-A281 PolarHBondContact O-N 3.45Å; E279-Q282 PolarHBondContact O-N 3.03Å; E279-E283 WeakPolarHBondContact O-CB 3.5Å; E279-E283 WeakPolarHBondContact O-CG 3.4Å; E279-E283 PolarHBondContact O-N 3.25Å
280	T	61.4	Low	62.4	Low	41 Å²	41	79.7 Å²	79.7	25%	0.252	41%	0.405	S	S	.	.	H	α-helix	trans	-67.5	-35.5	178.4	-50.9	0	0	0	0	112.1	Y160 I276 V278 R284	Y160-T280 HydrophobicContact CD1-CG2 4.39Å; Y160-T280 HydrophobicContact CE1-CG2 3.68Å; I276-T280 WeakPolarHBondContact O-CB 3.39Å; I276-T280 PolarHBondContact O-N 2.68Å; I276-T280 PolarHBondContact O-OG1 3Å; V278-T280 PolarHBondContact O-N 3.35Å; T280-R284 WeakPolarHBondContact O-CB 2.99Å; T280-R284 WeakPolarHBondContact O-CG 3.29Å; T280-R284 PolarHBondContact O-N 2.92Å
281	A	59	Low	62	Low	7 Å²	7	76 Å²	76	6%	0.058	38%	0.383	C	S	.	.	H	α-helix	trans	-69.3	-38.7	175.7	0	0	0	0	0	112	L277 V278 E279 R284 N285 I288	L277-A281 VanDerWaalsContact O-CB 3.24Å; L277-A281 WeakPolarHBondContact O-CB 3.4Å; L277-A281 PolarHBondContact O-N 3.17Å; V278-A281 PolarHBondContact O-N 3.33Å; E279-A281 PolarHBondContact O-N 3.45Å; A281-R284 PolarHBondContact O-N 3.32Å; A281-N285 PolarHBondContact O-N 2.99Å; A281-I288 HydrophobicContact CB-CG1 4.2Å
282	Q	58.5	Low	61.7	Low	134 Å²	134	70.8 Å²	70.8	63%	0.626	36%	0.364	S	S	*	.	H	α-helix	trans	-66.6	-40.2	175.2	-74.2	178.4	-27.6	0	0	112.1	V278 E279 R284	V278-Q282 HydrophobicContact CG1-CG 4.5Å; V278-Q282 WeakPolarHBondContact O-CB 3.31Å; V278-Q282 VanDerWaalsContact O-CG 3.32Å; V278-Q282 WeakPolarHBondContact O-CG 3.37Å; V278-Q282 PolarHBondContact O-N 3.46Å; E279-Q282 PolarHBondContact O-N 3.03Å; Q282-R284 PolarHBondContact O-N 3.09Å
283	E	61.2	Low	61.6	Low	151 Å²	151	72.8 Å²	72.8	71%	0.706	37%	0.373	S	S	*	.	H	α-helix	trans	-64	-24.1	175.3	-77	178.2	-175.6	0	0	113.5	E279	E279-E283 WeakPolarHBondContact O-CB 3.5Å; E279-E283 WeakPolarHBondContact O-CG 3.4Å; E279-E283 PolarHBondContact O-N 3.25Å
284	R	54.8	Low	61.7	Low	132 Å²	132	72 Å²	72	50%	0.498	37%	0.367	S	S	.	.	H	α-helix	trans	-103.6	-6.1	-173.2	-65.2	-63.6	-166.5	-165.6	-1.5	114.8	T280 A281 Q282 E286	T280-R284 WeakPolarHBondContact O-CB 2.99Å; T280-R284 WeakPolarHBondContact O-CG 3.29Å; T280-R284 PolarHBondContact O-N 2.92Å; A281-R284 PolarHBondContact O-N 3.32Å; Q282-R284 PolarHBondContact O-N 3.09Å; R284-E286 HydrophobicContact CB-CG 4.13Å; R284-E286 PolarHBondContact O-N 2.9Å; R284-E286 VanDerWaalsContact O-N 3.14Å
285	N	50.8	Low	61.8	Low	153 Å²	153	70.2 Å²	70.2	82%	0.818	36%	0.36	S	S	*	.	T	Hydrogen-bonded Turn	trans	51.1	31	-176.3	-87.3	-47.5	0	0	0	113.5	A281	A281-N285 PolarHBondContact O-N 2.99Å
286	E	56.5	Low	60.9	Low	70 Å²	70	66.1 Å²	66.1	33%	0.327	35%	0.346	S	S	.	.			trans	-90.6	137	178.1	-71.7	175.7	-178.7	0	0	110.1	Y165 R284 I288	Y165-E286 VanDerWaalsContact CE1-OE2 3.31Å; Y165-E286 WeakPolarHBondContact CE1-OE2 3.29Å; Y165-E286 PolarHBondContact OH-OE1 2.9Å; Y165-E286 PolarHBondContact OH-OE2 2.85Å; R284-E286 HydrophobicContact CB-CG 4.13Å; R284-E286 PolarHBondContact O-N 2.9Å; R284-E286 VanDerWaalsContact O-N 3.14Å; E286-I288 PolarHBondContact O-N 3.19Å
287	P	54.3	Low	59.8	Low	103 Å²	103	64.2 Å²	64.2	67%	0.669	34%	0.338	S	S	*	.			trans	-62.3	115	176.6	25.4	-32.3	0	0	0	109.3	F289	P287-F289 PolarHBondContact O-N 2.68Å
288	I	57.3	Low	58.4	Low	64 Å²	64	68.8 Å²	68.8	33%	0.328	36%	0.36	S	S	.	.			trans	-58.4	138	-179.4	-51.1	169.9	0	0	0	109.2	A281 E286 P290 I293	A281-I288 HydrophobicContact CB-CG1 4.2Å; E286-I288 PolarHBondContact O-N 3.19Å; I288-P290 WeakPolarHBondContact O-CD 3.39Å; I288-P290 VanDerWaalsContact O-N 3.15Å; I288-I293 HydrophobicContact CB-CD1 4.01Å; I288-I293 HydrophobicContact CD1-CD1 4.34Å; I288-I293 HydrophobicContact CG2-CD1 3.37Å; I288-I293 HydrophobicContact CG2-CG1 4.39Å
289	F	60.1	Low	57.1	Low	39 Å²	39	69 Å²	69	17%	0.171	36%	0.361	C	S	.	.			trans	-44	114.4	-169.3	-61.6	-73	0	0	0	113.4	Y160 I168 L172 P287 A291 L292	Y160-F289 HydrophobicContact CD2-CE2 4.02Å; Y160-F289 HydrophobicContact CD2-CZ 4.01Å; Y160-F289 HydrophobicContact CE2-CE2 4.18Å; Y160-F289 HydrophobicContact CE2-CZ 4.18Å; I168-F289 HydrophobicContact CB-CE1 4.37Å; I168-F289 HydrophobicContact CB-CZ 4.33Å; I168-F289 HydrophobicContact CD1-CZ 4.16Å; I168-F289 HydrophobicContact CG2-CD1 4.23Å; I168-F289 HydrophobicContact CG2-CE1 3.54Å; I168-F289 HydrophobicContact CG2-CE2 4.11Å; I168-F289 HydrophobicContact CG2-CZ 3.49Å; I168-F289 VanDerWaalsContact CG2-CZ 3.49Å; L172-F289 HydrophobicContact CD1-CB 3.84Å; L172-F289 HydrophobicContact CD1-CD1 3.71Å; L172-F289 HydrophobicContact CD1-CD2 4.44Å; L172-F289 HydrophobicContact CD1-CE1 4.42Å; L172-F289 HydrophobicContact CD1-CG 3.73Å; P287-F289 PolarHBondContact O-N 2.68Å; F289-A291 PolarHBondContact O-N 3.4Å; F289-L292 HydrophobicContact CB-CD1 4.1Å; F289-L292 HydrophobicContact CD2-CD1 4.37Å; F289-L292 PolarHBondContact O-N 3.03Å; F289-L292 VanDerWaalsContact O-N 3.08Å
290	P	52	Low	55.4	Low	70 Å²	70	72.9 Å²	72.9	46%	0.455	37%	0.372	S	S	.	.	T	Hydrogen-bonded Turn	trans	-57.3	-24.2	-174.4	-27.8	34.1	0	0	0	115.1	I219 I288	I219-P290 WeakPolarHBondContact O-CB 3.36Å; I288-P290 WeakPolarHBondContact O-CD 3.39Å; I288-P290 VanDerWaalsContact O-N 3.15Å
291	A	57.8	Low	54.1	Low	24 Å²	24	76.5 Å²	76.5	20%	0.198	39%	0.39	C	S	.	.	T	Hydrogen-bonded Turn	trans	-83.3	-7.1	-177.7	0	0	0	0	0	114.6	I219 F289 L392	I219-A291 HydrophobicContact CG2-CB 3.71Å; F289-A291 PolarHBondContact O-N 3.4Å; A291-L392 WeakPolarHBondContact O-CD1 3.32Å
292	L	64.7	Low	52.9	Low	73 Å²	73	81 Å²	81	38%	0.382	42%	0.416	S	S	.	.	T	Hydrogen-bonded Turn	trans	-112.2	-15.5	-174.4	-74.1	169.6	0	0	0	113.9	L172 F289 L392	L172-L292 HydrophobicContact CD1-CD1 4.13Å; L172-L292 HydrophobicContact CD2-CD1 4.13Å; L172-L292 HydrophobicContact CD2-CD2 4.48Å; L172-L292 HydrophobicContact CD2-CG 4.32Å; F289-L292 HydrophobicContact CB-CD1 4.1Å; F289-L292 HydrophobicContact CD2-CD1 4.37Å; F289-L292 PolarHBondContact O-N 3.03Å; F289-L292 VanDerWaalsContact O-N 3.08Å; L292-L392 PolarHBondContact O-N 3.48Å
293	I	69.9	Low	51.5	Low	45 Å²	45	81.2 Å²	81.2	23%	0.231	42%	0.422	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-126.5	133.7	-174.4	-61.3	-177.7	0	0	0	110.2	L232 I288 K389	L232-I293 WeakPolarHBondContact CD2-O 3.34Å; I288-I293 HydrophobicContact CB-CD1 4.01Å; I288-I293 HydrophobicContact CD1-CD1 4.34Å; I288-I293 HydrophobicContact CG2-CD1 3.37Å; I288-I293 HydrophobicContact CG2-CG1 4.39Å; I293-K389 HydrophobicContact CG2-CB 3.71Å; I293-K389 HydrophobicContact CG2-CD 4.22Å; I293-K389 HydrophobicContact CG2-CG 4.09Å
294	Y	68.9	Low	50.3	Low	7 Å²	7	83 Å²	83	3%	0.027	43%	0.432	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-82.4	117.6	167.3	-176.4	-91	0	0	0	109.9	P93 Q229 L232 I233 K389 L390 F395	P93-Y294 HydrophobicContact CB-CE1 4.17Å; P93-Y294 HydrophobicContact CB-CE2 4.04Å; P93-Y294 VanDerWaalsContact CB-OH 3.26Å; P93-Y294 WeakPolarHBondContact CB-OH 3.37Å; P93-Y294 HydrophobicContact CG-CE1 3.72Å; P93-Y294 HydrophobicContact CG-CE2 4.48Å; P93-Y294 WeakPolarHBondContact CG-OH 3.45Å; Q229-Y294 HydrophobicContact CB-CE2 3.8Å; Q229-Y294 HydrophobicContact CG-CE2 3.67Å; Q229-Y294 WeakPolarHBondContact CG-OH 3.49Å; Q229-Y294 PolarHBondContact NE2-OH 2.79Å; L232-Y294 HydrophobicContact CB-CD2 4.15Å; L232-Y294 HydrophobicContact CD2-CD2 4.01Å; I233-Y294 HydrophobicContact CG1-CE2 4.46Å; Y294-K389 WeakPolarHBondContact O-CA 3.32Å; Y294-L390 WeakPolarHBondContact CB-O 3.32Å; Y294-L390 PolarHBondContact N-O 3.25Å; Y294-L390 PolarHBondContact O-N 2.98Å; Y294-L390 VanDerWaalsContact O-N 3.09Å; Y294-F395 HydrophobicContact CD1-CE2 4.33Å; Y294-F395 AromaticContact CD1-CZ 3.86Å; Y294-F395 HydrophobicContact CD1-CZ 3.86Å; Y294-F395 HydrophobicContact CD2-CZ 4.06Å; Y294-F395 HydrophobicContact CE1-CZ 4.33Å; Y294-F395 HydrophobicContact CG-CE2 4.01Å; Y294-F395 AromaticContact CG-CZ 3.72Å; Y294-F395 HydrophobicContact CG-CZ 3.72Å
295	S	67.6	Low	49.2	Very low	29 Å²	29	80.5 Å²	80.5	20%	0.203	44%	0.44	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-98.2	117.8	172.6	-159.7	0	0	0	0	110	Q229 T297	Q229-S295 PolarHBondContact NE2-O 2.97Å; S295-T297 PolarHBondContact OG-O 2.94Å
296	S	50.3	Low	48.4	Very low	9 Å²	9	80.6 Å²	80.6	6%	0.063	44%	0.441	C	S	.	.	S	Bend	trans	-75.2	-30.4	178.5	55.8	0	0	0	0	112.8	Q229 V388	Q229-S296 PolarHBondContact NE2-O 2.97Å; Q229-S296 VanDerWaalsContact NE2-O 3.16Å; S296-V388 PolarHBondContact OG-N 3.43Å; S296-V388 PolarHBondContact OG-O 3.32Å
297	T	46.4	Very low	47.6	Very low	27 Å²	27	83.2 Å²	83.2	17%	0.166	46%	0.461	C	S	.	.	S	Bend	trans	-125.8	162.7	179.8	-41.1	0	0	0	0	111.2	S295 V299 G387	S295-T297 PolarHBondContact OG-O 2.94Å; T297-V299 PolarHBondContact O-N 3.33Å; T297-V299 VanDerWaalsContact O-N 3.11Å; T297-G387 VanDerWaalsContact OG1-CA 3.3Å; T297-G387 WeakPolarHBondContact OG1-CA 3.49Å
298	M	39.2	Very low	46.5	Very low	127 Å²	127	85.6 Å²	85.6	63%	0.626	47%	0.469	S	S	*	.			trans	-55.8	107.7	-173.7	-52.5	165.3	80.9	0	0	110.7	L225	L225-M298 HydrophobicContact CD1-CB 4.19Å; L225-M298 HydrophobicContact CD1-CG 3.78Å
299	V	38.8	Very low	45.3	Very low	73 Å²	73	85.5 Å²	85.5	44%	0.442	48%	0.483	S	S	.	.			trans	-113	75.9	159.4	-178.3	0	0	0	0	106.3	T297	T297-V299 PolarHBondContact O-N 3.33Å; T297-V299 VanDerWaalsContact O-N 3.11Å
300	W	33	Very low	44	Very low	152 Å²	152	89.8 Å²	89.8	58%	0.576	52%	0.515	S	S	*	.			trans	-97	99.8	145.5	-98.8	85	0	0	0	105	K222 V302	K222-W300 HydrophobicContact CB-CH2 4.42Å; K222-W300 HydrophobicContact CB-CZ2 3.84Å; K222-W300 HydrophobicContact CD-CH2 3.81Å; K222-W300 HydrophobicContact CD-CZ2 3.56Å; K222-W300 HydrophobicContact CG-CH2 4.22Å; K222-W300 HydrophobicContact CG-CZ2 3.51Å; W300-V302 HydrophobicContact CB-CG2 4.46Å; W300-V302 PolarHBondContact O-N 2.92Å
301	L	34.3	Very low	43	Very low	118 Å²	118	96.3 Å²	96.3	62%	0.618	54%	0.536	S	S	*	.			trans	-58.3	85.3	158.7	-108.6	151.9	0	0	0	106.5	N303	L301-N303 HydrophobicContact CD2-CB 4.26Å; L301-N303 PolarHBondContact O-N 3.35Å
302	V	33.8	Very low	41.7	Very low	101 Å²	101	106 Å²	106	61%	0.612	57%	0.568	S	S	*	*			trans	-69.2	78.4	159.3	177.8	0	0	0	0	105	W300 M304 A305	W300-V302 HydrophobicContact CB-CG2 4.46Å; W300-V302 PolarHBondContact O-N 2.92Å; V302-M304 VanDerWaalsContact C-N 3.27Å; V302-A305 HydrophobicContact CG1-CB 3.64Å
303	N	31	Very low	40	Very low	139 Å²	139	110.1 Å²	110.1	74%	0.743	59%	0.59	S	S	*	*			trans	-97.2	23.1	162.8	-159.4	32.4	0	0	0	111.1	L301	L301-N303 HydrophobicContact CD2-CB 4.26Å; L301-N303 PolarHBondContact O-N 3.35Å
304	M	34.3	Very low	38.2	Very low	188 Å²	188	113 Å²	113	93%	0.926	62%	0.615	S	S	*	*	S	Bend	trans	-149.4	63.7	172.4	-82.9	-157.2	162.2	0	0	111.1	V302	V302-M304 VanDerWaalsContact C-N 3.27Å
305	A	32.6	Very low	36.3	Very low	80 Å²	80	118.7 Å²	118.7	66%	0.661	65%	0.65	S	S	*	*			trans	-147.5	56	153.8	0	0	0	0	0	109	V302	V302-A305 HydrophobicContact CG1-CB 3.64Å
306	D	34.3	Very low	34.5	Very low	155 Å²	155	126.2 Å²	126.2	83%	0.829	68%	0.682	S	S	*	*			trans	-111.2	88.8	151.6	-159.3	5.8	0	0	0	107
307	T	38.9	Very low	33.4	Very low	124 Å²	124	130.6 Å²	130.6	76%	0.761	72%	0.719	S	S	*	*			trans	-165.7	76.1	160.1	4.8	0	0	0	0	105.8
308	D	31.9	Very low	32.6	Very low	154 Å²	154	135.5 Å²	135.5	82%	0.824	75%	0.749	S	S	*	*				169.2	128.2	122.8	-86.7	-22.6	0	0	0	110.2
309	G	31.5	Very low	32.3	Very low	62 Å²	62	135.1 Å²	135.1	64%	0.639	76%	0.756	S	S	*	*			trans	-61.1	164	-175.3	0	0	0	0	0	114.6	K311	G309-K311 PolarHBondContact O-N 3.2Å
310	P	33.2	Very low	32	Very low	129 Å²	129	136.9 Å²	136.9	84%	0.838	77%	0.769	S	S	*	*			trans	-74.9	115.4	-166.5	28.5	-33	0	0	0	112.2	R312	P310-R312 PolarHBondContact O-N 3.25Å
311	K	30.2	Very low	31.8	Very low	206 Å²	206	139 Å²	139	90%	0.896	79%	0.785	S	S	*	*			trans	-73.3	99.6	157.3	-78.8	-177.7	178.7	177.2	0	108.9	G309 N313	G309-K311 PolarHBondContact O-N 3.2Å; K311-N313 PolarHBondContact O-N 3.41Å
312	R	30.3	Very low	31.3	Very low	228 Å²	228	141.5 Å²	141.5	86%	0.86	79%	0.794	S	S	*	*			trans	-71.3	112.9	163.9	-96.4	176.8	156.3	168.7	-6.7	109.2	P310	P310-R312 PolarHBondContact O-N 3.25Å
313	N	29.3	Very low	30.9	Very low	159 Å²	159	144.4 Å²	144.4	85%	0.85	80%	0.801	S	S	*	*			trans	-77.3	123.3	154.2	-86.6	-8.5	0	0	0	107.9	K311	K311-N313 PolarHBondContact O-N 3.41Å
314	S	32.5	Very low	30.7	Very low	107 Å²	107	143.2 Å²	143.2	75%	0.748	80%	0.798	S	S	*	*			trans	-134	109.2	161.8	-61.3	0	0	0	0	107.7
315	T	29.4	Very low	30.3	Very low	126 Å²	126	142.4 Å²	142.4	77%	0.773	79%	0.793	S	S	*	*			trans	-70.8	156.5	168.1	-32.4	0	0	0	0	109.4
316	E	29.2	Very low	30.1	Very low	186 Å²	186	146.3 Å²	146.3	87%	0.869	80%	0.802	S	S	*	*			trans	82.9	105.6	166.4	-65.8	178.3	114.6	0	0	118.2
317	A	27.7	Very low	29.8	Very low	102 Å²	102	144.2 Å²	144.2	84%	0.843	80%	0.8	S	S	*	*				178	114.9	95.9	0	0	0	0	0	110.9
318	T	29.3	Very low	29.3	Very low	130 Å²	130	143.3 Å²	143.3	80%	0.798	81%	0.805	S	S	*	*			trans	-76.5	155.4	159.6	-25.2	0	0	0	0	108.2
319	P	32	Very low	29.2	Very low	119 Å²	119	142.5 Å²	142.5	77%	0.773	81%	0.805	S	S	*	*				-153.6	-161.5	85.9	47.6	-26.9	0	0	0	111.8
320	P	34.1	Very low	29.1	Very low	110 Å²	110	148.2 Å²	148.2	71%	0.714	82%	0.815	S	S	*	*				-120.8	160.9	-114	25.2	-1.3	0	0	0	113.5
321	Q	27.7	Very low	28.8	Very low	197 Å²	197	147.6 Å²	147.6	92%	0.921	81%	0.814	S	S	*	*			trans	-150.5	124.4	150.9	-115	167.1	14.3	0	0	113.1
322	Q	24.8	Very low	29.3	Very low	170 Å²	170	143.9 Å²	143.9	79%	0.794	81%	0.811	S	S	*	*			trans	-53.3	157.2	169.1	-67.7	152.8	-35.3	0	0	110.3
323	Q	25.7	Very low	29.2	Very low	162 Å²	162	137.3 Å²	137.3	76%	0.757	81%	0.805	S	S	*	*				-178.4	143.6	50.6	-141.1	160.8	14.6	0	0	110
324	T	25.9	Very low	29.5	Very low	113 Å²	113	135.7 Å²	135.7	69%	0.693	80%	0.804	S	S	*	*			trans	59.2	103.9	146	33.7	0	0	0	0	122.9
325	Q	26.3	Very low	29.5	Very low	172 Å²	172	135.7 Å²	135.7	80%	0.804	80%	0.804	S	S	*	*				53.9	109.3	106	-154.6	168.6	50.5	0	0	119
326	D	28.5	Very low	29.9	Very low	162 Å²	162	134.9 Å²	134.9	87%	0.866	80%	0.803	S	S	*	*				-162.8	152.2	120.6	-109.3	-24.8	0	0	0	113.9
327	S	27.5	Very low	30.4	Very low	111 Å²	111	132.3 Å²	132.3	78%	0.776	80%	0.802	S	S	*	*			trans	-90.7	145.6	-169	-54.2	0	0	0	0	112.6
328	A	29	Very low	30.9	Very low	105 Å²	105	132.8 Å²	132.8	87%	0.868	80%	0.8	S	S	*	*				177.3	145.6	129.2	0	0	0	0	0	112.4
329	V	29.6	Very low	31.5	Very low	136 Å²	136	135 Å²	135	82%	0.824	80%	0.801	S	S	*	*			trans	-79.4	135.1	-172	172	0	0	0	0	111.5
330	E	28.6	Very low	32	Very low	183 Å²	183	136.9 Å²	136.9	86%	0.855	81%	0.805	S	S	*	*				175	134.2	124.3	-116.5	162.3	-179.1	0	0	112.1
331	S	26.6	Very low	32.6	Very low	116 Å²	116	137.6 Å²	137.6	81%	0.811	80%	0.802	S	S	*	*			trans	-128.6	164.6	163.5	-71.4	0	0	0	0	106.1
332	P	40.8	Very low	33.8	Very low	127 Å²	127	131.1 Å²	131.1	83%	0.825	79%	0.788	S	S	*	*			cis	-133.4	-175.7	16.2	39.8	-19.2	0	0	0	111.6
333	A	28.1	Very low	35.2	Very low	90 Å²	90	125.8 Å²	125.8	74%	0.744	78%	0.779	S	S	*	*			cis	-158.7	148.8	16.5	0	0	0	0	0	108.2
334	P	35.3	Very low	36	Very low	126 Å²	126	125.1 Å²	125.1	82%	0.818	77%	0.774	S	S	*	*			trans	-99.8	143.4	169.9	35.1	-27.4	0	0	0	112.3
335	S	32.9	Very low	37.9	Very low	107 Å²	107	123.3 Å²	123.3	75%	0.748	76%	0.763	S	S	*	*			trans	-67.2	145.6	165.2	43.2	0	0	0	0	112.4
336	S	37.3	Very low	39.5	Very low	109 Å²	109	120.3 Å²	120.3	76%	0.762	76%	0.761	S	S	*	*			trans	68.8	129	163.5	41.8	0	0	0	0	119.3
337	P	40.2	Very low	40.9	Very low	132 Å²	132	115.7 Å²	115.7	86%	0.857	74%	0.741	S	S	*	*	P	Polyproline II helix	trans	-92.8	116.6	159.8	31.4	-21.8	0	0	0	110.5
338	S	37.6	Very low	42.5	Very low	112 Å²	112	116.3 Å²	116.3	78%	0.783	73%	0.726	S	S	*	*	P	Polyproline II helix	trans	-67.2	146.2	161.8	45.6	0	0	0	0	110.9	D340	S338-D340 PolarHBondContact O-N 3.32Å
339	Q	41.8	Very low	44.1	Very low	175 Å²	175	114.9 Å²	114.9	82%	0.818	71%	0.707	S	S	*	*	P	Polyproline II helix	trans	-58.2	131.3	173	-76.7	168.1	-47.4	0	0	111.2	D341	Q339-D341 PolarHBondContact O-N 2.96Å
340	D	44	Very low	45.5	Very low	160 Å²	160	111.6 Å²	111.6	86%	0.856	69%	0.69	S	S	*	*			trans	-84.2	80.1	177.2	-171.1	20	0	0	0	109.6	S338 G342	S338-D340 PolarHBondContact O-N 3.32Å; D340-G342 VanDerWaalsContact C-N 3.31Å; D340-G342 PolarHBondContact O-N 3.03Å
341	D	45.2	Very low	46.9	Very low	124 Å²	124	108.8 Å²	108.8	66%	0.663	68%	0.677	S	S	*	*			trans	-86.2	70.6	174.4	-80.4	-21.2	0	0	0	110.4	Q339 G343 F344	Q339-D341 PolarHBondContact O-N 2.96Å; D341-G343 PolarHBondContact O-N 3.48Å; D341-F344 PolarHBondContact O-N 3.31Å
342	G	53.4	Low	48.2	Very low	61 Å²	61	107.8 Å²	107.8	63%	0.629	66%	0.659	S	S	*	*	T	Hydrogen-bonded Turn	trans	39.6	28.9	147.4	0	0	0	0	0	120.3	D340 F344	D340-G342 VanDerWaalsContact C-N 3.31Å; D340-G342 PolarHBondContact O-N 3.03Å; G342-F344 VanDerWaalsContact C-N 3.31Å; G342-F344 WeakPolarHBondContact O-CD2 3.47Å; G342-F344 PolarHBondContact O-N 3.27Å
343	G	54.1	Low	48.9	Very low	58 Å²	58	109 Å²	109	60%	0.598	65%	0.654	S	S	*	*	T	Hydrogen-bonded Turn	trans	72.6	6.8	177	0	0	0	0	0	117	D341	D341-G343 PolarHBondContact O-N 3.48Å
344	F	42.4	Very low	50.1	Low	149 Å²	149	113 Å²	113	65%	0.654	66%	0.657	S	S	*	*			trans	-108.7	72	177.7	-75.7	-86.5	0	0	0	111.2	D341 G342 W348	D341-F344 PolarHBondContact O-N 3.31Å; G342-F344 VanDerWaalsContact C-N 3.31Å; G342-F344 WeakPolarHBondContact O-CD2 3.47Å; G342-F344 PolarHBondContact O-N 3.27Å; F344-W348 AromaticContact CD1-CE3 3.89Å; F344-W348 HydrophobicContact CD1-CE3 3.89Å; F344-W348 AromaticContact CD1-CZ3 3.89Å; F344-W348 HydrophobicContact CD1-CZ3 3.89Å; F344-W348 AromaticContact CE1-CE3 4Å; F344-W348 HydrophobicContact CE1-CE3 4Å; F344-W348 HydrophobicContact CE1-CH2 4.1Å; F344-W348 AromaticContact CE1-CZ3 3.51Å; F344-W348 HydrophobicContact CE1-CZ3 3.51Å
345	T	65.9	Low	50.8	Low	75 Å²	75	117.2 Å²	117.2	46%	0.46	66%	0.657	S	S	.	*			trans	-76.4	151.5	172	55.5	0	0	0	0	110.7	S347 W348 V349	T345-S347 WeakPolarHBondContact CB-OG 3.4Å; T345-S347 PolarHBondContact O-N 2.87Å; T345-S347 VanDerWaalsContact O-N 3.15Å; T345-S347 PolarHBondContact OG1-OG 2.83Å; T345-W348 WeakPolarHBondContact O-CA 3.48Å; T345-W348 WeakPolarHBondContact O-CB 3.41Å; T345-W348 PolarHBondContact O-N 2.78Å; T345-W348 PolarHBondContact OG1-N 2.91Å; T345-V349 PolarHBondContact O-N 2.99Å
346	S	59.8	Low	51.8	Low	108 Å²	108	117 Å²	117	76%	0.755	65%	0.647	S	S	*	*	H	α-helix	trans	-56.1	-30.7	175.2	56.3	0	0	0	0	112.5	S350	S346-S350 PolarHBondContact O-N 3.26Å; S346-S350 VanDerWaalsContact O-N 3.14Å; S346-S350 PolarHBondContact O-OG 3.48Å
347	S	58.2	Low	52.6	Low	66 Å²	66	114.3 Å²	114.3	46%	0.462	64%	0.636	S	S	.	*	H	α-helix	trans	-63.1	-38.8	171.1	43.1	0	0	0	0	113.1	T345 S350 Q351	T345-S347 WeakPolarHBondContact CB-OG 3.4Å; T345-S347 PolarHBondContact O-N 2.87Å; T345-S347 VanDerWaalsContact O-N 3.15Å; T345-S347 PolarHBondContact OG1-OG 2.83Å; S347-S350 WeakPolarHBondContact CA-OG 3.42Å; S347-S350 PolarHBondContact O-N 3.4Å; S347-S350 PolarHBondContact O-OG 3.27Å; S347-Q351 WeakPolarHBondContact O-CB 3.36Å; S347-Q351 PolarHBondContact O-N 3.12Å; S347-Q351 VanDerWaalsContact O-N 3.08Å
348	W	62.5	Low	52.9	Low	123 Å²	123	116.7 Å²	116.7	47%	0.466	64%	0.635	S	S	.	*	H	α-helix	trans	-67.4	-42.6	179.4	-166.4	91.8	0	0	0	111.9	F344 T345 Q351 Q352	F344-W348 AromaticContact CD1-CE3 3.89Å; F344-W348 HydrophobicContact CD1-CE3 3.89Å; F344-W348 AromaticContact CD1-CZ3 3.89Å; F344-W348 HydrophobicContact CD1-CZ3 3.89Å; F344-W348 AromaticContact CE1-CE3 4Å; F344-W348 HydrophobicContact CE1-CE3 4Å; F344-W348 HydrophobicContact CE1-CH2 4.1Å; F344-W348 AromaticContact CE1-CZ3 3.51Å; F344-W348 HydrophobicContact CE1-CZ3 3.51Å; T345-W348 WeakPolarHBondContact O-CA 3.48Å; T345-W348 WeakPolarHBondContact O-CB 3.41Å; T345-W348 PolarHBondContact O-N 2.78Å; T345-W348 PolarHBondContact OG1-N 2.91Å; W348-Q351 PolarHBondContact O-N 3.34Å; W348-Q352 PolarHBondContact O-N 2.86Å
349	V	61.5	Low	53.6	Low	75 Å²	75	117.8 Å²	117.8	46%	0.455	63%	0.632	S	S	.	*	H	α-helix	trans	-61.9	-45.6	175.7	177.6	0	0	0	0	111.2	T345 Q351 Q352 E353	T345-V349 PolarHBondContact O-N 2.99Å; V349-Q351 PolarHBondContact O-N 3.01Å; V349-Q352 PolarHBondContact O-N 3.33Å; V349-E353 PolarHBondContact O-N 3.46Å
350	S	58.8	Low	53.8	Low	68 Å²	68	117 Å²	117	48%	0.476	63%	0.628	S	S	.	*	H	α-helix	trans	-65.1	-28.1	178.1	64.7	0	0	0	0	113.4	S346 S347	S346-S350 PolarHBondContact O-N 3.26Å; S346-S350 VanDerWaalsContact O-N 3.14Å; S346-S350 PolarHBondContact O-OG 3.48Å; S347-S350 WeakPolarHBondContact CA-OG 3.42Å; S347-S350 PolarHBondContact O-N 3.4Å; S347-S350 PolarHBondContact O-OG 3.27Å
351	Q	57.7	Low	54.1	Low	123 Å²	123	115.1 Å²	115.1	58%	0.575	62%	0.623	S	S	*	*	H	α-helix	trans	-84	-22.9	179.9	-160.9	153.8	14.7	0	0	112.9	S347 W348 V349	S347-Q351 WeakPolarHBondContact O-CB 3.36Å; S347-Q351 PolarHBondContact O-N 3.12Å; S347-Q351 VanDerWaalsContact O-N 3.08Å; W348-Q351 PolarHBondContact O-N 3.34Å; V349-Q351 PolarHBondContact O-N 3.01Å
352	Q	55.3	Low	54.9	Low	95 Å²	95	113 Å²	113	44%	0.444	61%	0.614	S	S	.	*	H	α-helix	trans	-70.2	-43.2	171.9	-172	179.2	-14.6	0	0	111.7	W348 V349 H354 R355 L356	W348-Q352 PolarHBondContact O-N 2.86Å; V349-Q352 PolarHBondContact O-N 3.33Å; Q352-H354 PolarHBondContact O-N 3.25Å; Q352-R355 PolarHBondContact O-N 3.42Å; Q352-L356 HydrophobicContact CG-CD1 4.13Å; Q352-L356 PolarHBondContact O-N 3.41Å
353	E	53.9	Low	55.1	Low	154 Å²	154	117 Å²	117	72%	0.72	62%	0.616	S	S	*	*	H	α-helix	trans	-59.6	-35.9	176.3	-88.2	-174.7	132.4	0	0	112.4	V349	V349-E353 PolarHBondContact O-N 3.46Å
354	H	54.1	Low	55.1	Low	173 Å²	173	121.2 Å²	121.2	80%	0.801	62%	0.621	S	S	*	*	H	α-helix	trans	-79.1	-18.6	-175.9	-134.2	-66.9	0	0	0	114.3	Q352	Q352-H354 PolarHBondContact O-N 3.25Å
355	R	50.9	Low	55.8	Low	214 Å²	214	117.5 Å²	117.5	81%	0.808	61%	0.61	S	S	*	*	H	α-helix	trans	-96.1	-27.1	-179.4	-85.1	-158	-157.7	-153	7.3	114.9	Q352	Q352-R355 PolarHBondContact O-N 3.42Å
356	L	53.8	Low	55.4	Low	104 Å²	104	122.6 Å²	122.6	55%	0.545	62%	0.621	S	S	.	*	H	α-helix	trans	-102.7	-5.6	-171.4	-82.2	159.3	0	0	0	114.7	Q352 L359	Q352-L356 HydrophobicContact CG-CD1 4.13Å; Q352-L356 PolarHBondContact O-N 3.41Å; L356-L359 HydrophobicContact CB-CD1 4.06Å; L356-L359 HydrophobicContact CD2-CD1 4.23Å
357	G	52.7	Low	55.2	Low	51 Å²	51	124.9 Å²	124.9	53%	0.526	61%	0.613	S	S	.	*			trans	60.8	175.5	-172.6	0	0	0	0	0	111.8	L359	G357-L359 PolarHBondContact O-N 2.98Å
358	Q	46.9	Very low	55.2	Low	183 Å²	183	128.2 Å²	128.2	86%	0.855	62%	0.621	S	S	*	*			trans	-72.8	90	-179.1	-157.8	171.9	27.4	0	0	109.3	Q360	Q358-Q360 VanDerWaalsContact C-N 3.3Å; Q358-Q360 PolarHBondContact O-N 2.96Å
359	L	52.4	Low	55	Low	134 Å²	134	127.7 Å²	127.7	70%	0.702	63%	0.627	S	S	*	*			trans	-68.4	88	173.9	-81.1	163	0	0	0	109.4	L356 G357	L356-L359 HydrophobicContact CB-CD1 4.06Å; L356-L359 HydrophobicContact CD2-CD1 4.23Å; G357-L359 PolarHBondContact O-N 2.98Å
360	Q	47.4	Very low	54.8	Low	159 Å²	159	131.4 Å²	131.4	74%	0.743	64%	0.639	S	S	*	*			trans	-80	115.4	162	-98.6	179.2	-23.8	0	0	108.5	Q358 T362	Q358-Q360 VanDerWaalsContact C-N 3.3Å; Q358-Q360 PolarHBondContact O-N 2.96Å; Q360-T362 PolarHBondContact O-N 3.32Å; Q360-T362 VanDerWaalsContact O-N 3.09Å
361	T	50	Low	54.3	Low	121 Å²	121	135.7 Å²	135.7	74%	0.742	65%	0.651	S	S	*	*			trans	-70.4	101.1	168.1	61.9	0	0	0	0	108
362	T	62.2	Low	53.9	Low	80 Å²	80	135.7 Å²	135.7	49%	0.491	65%	0.653	S	S	.	*			trans	-69.6	148.3	173.2	-40	0	0	0	0	109.5	Q360 E364 T365 R366	Q360-T362 PolarHBondContact O-N 3.32Å; Q360-T362 VanDerWaalsContact O-N 3.09Å; T362-E364 PolarHBondContact O-N 3.42Å; T362-E364 VanDerWaalsContact O-N 3.12Å; T362-T365 PolarHBondContact O-N 2.96Å; T362-T365 VanDerWaalsContact O-N 3.16Å; T362-R366 PolarHBondContact O-N 3.41Å
363	E	56	Low	53.3	Low	143 Å²	143	137 Å²	137	67%	0.668	67%	0.67	S	S	*	*	H	α-helix	trans	-56.1	-29.3	178.9	-73.5	-168.6	154.6	0	0	112.9	R366 R367	E363-R366 PolarHBondContact O-N 3.18Å; E363-R367 WeakPolarHBondContact O-CG 3.44Å; E363-R367 PolarHBondContact O-N 3.25Å; E363-R367 VanDerWaalsContact O-N 3.16Å
364	E	54.7	Low	52.8	Low	147 Å²	147	134.2 Å²	134.2	69%	0.687	67%	0.668	S	S	*	*	H	α-helix	trans	-67.2	-45.3	177.3	-70.9	-178	149.9	0	0	112.6	T362 R366 R367 E368	T362-E364 PolarHBondContact O-N 3.42Å; T362-E364 VanDerWaalsContact O-N 3.12Å; E364-R366 PolarHBondContact O-N 3.45Å; E364-R367 WeakPolarHBondContact O-CB 3.43Å; E364-R367 PolarHBondContact O-N 2.87Å; E364-E368 PolarHBondContact O-N 2.9Å
365	T	57.8	Low	52.3	Low	72 Å²	72	131 Å²	131	44%	0.442	67%	0.671	S	S	.	*	H	α-helix	trans	-63.6	-31.7	177.2	-45.2	0	0	0	0	111.7	T362 I369	T362-T365 PolarHBondContact O-N 2.96Å; T362-T365 VanDerWaalsContact O-N 3.16Å; T365-I369 WeakPolarHBondContact O-CG1 3.41Å; T365-I369 PolarHBondContact O-N 2.97Å
366	R	56.8	Low	51.9	Low	181 Å²	181	130.5 Å²	130.5	68%	0.683	67%	0.669	S	S	*	*	H	α-helix	trans	-69.9	-34.8	175	-159	177.3	-162.9	160.2	4.9	111.9	T362 E363 E364 Q370	T362-R366 PolarHBondContact O-N 3.41Å; E363-R366 PolarHBondContact O-N 3.18Å; E364-R366 PolarHBondContact O-N 3.45Å; R366-Q370 PolarHBondContact O-N 3Å
367	R	55.9	Low	51.3	Low	157 Å²	157	130.4 Å²	130.4	59%	0.592	68%	0.675	S	S	*	*	H	α-helix	trans	-72.6	-38.3	177.5	-72.8	177.1	-175.5	-175	5.6	112.4	E363 E364 Q370 Q371	E363-R367 WeakPolarHBondContact O-CG 3.44Å; E363-R367 PolarHBondContact O-N 3.25Å; E363-R367 VanDerWaalsContact O-N 3.16Å; E364-R367 WeakPolarHBondContact O-CB 3.43Å; E364-R367 PolarHBondContact O-N 2.87Å; R367-Q370 PolarHBondContact O-N 3.47Å; R367-Q371 WeakPolarHBondContact O-CG 3.29Å; R367-Q371 PolarHBondContact O-N 3.45Å
368	E	57.3	Low	50.7	Low	135 Å²	135	133.6 Å²	133.6	63%	0.631	69%	0.686	S	S	*	*	H	α-helix	trans	-63.2	-40.6	174.8	-87.1	-175.8	134.2	0	0	112.4	E364 Q370 Q371 M372	E364-E368 PolarHBondContact O-N 2.9Å; E368-Q370 VanDerWaalsContact C-N 3.28Å; E368-Q370 PolarHBondContact O-N 3.47Å; E368-Q371 PolarHBondContact O-N 3.47Å; E368-M372 PolarHBondContact O-N 3.4Å
369	I	58.7	Low	50.4	Low	113 Å²	113	128.7 Å²	128.7	58%	0.579	68%	0.677	S	S	*	*	H	α-helix	trans	-68.5	-30.2	176.7	-63.7	170	0	0	0	111.5	T365 Q371 M372	T365-I369 WeakPolarHBondContact O-CG1 3.41Å; T365-I369 PolarHBondContact O-N 2.97Å; I369-Q371 VanDerWaalsContact C-N 3.32Å; I369-M372 HydrophobicContact CB-CE 4.18Å; I369-M372 HydrophobicContact CG1-CE 3.92Å; I369-M372 HydrophobicContact CG2-CE 4.26Å
370	Q	57.3	Low	49.7	Very low	153 Å²	153	130.8 Å²	130.8	72%	0.715	68%	0.683	S	S	*	*	H	α-helix	trans	-76.3	-18	175.1	-120.2	161	-9.5	0	0	113.8	R366 R367 E368	R366-Q370 PolarHBondContact O-N 3Å; R367-Q370 PolarHBondContact O-N 3.47Å; E368-Q370 VanDerWaalsContact C-N 3.28Å; E368-Q370 PolarHBondContact O-N 3.47Å
371	Q	49.3	Very low	49.1	Very low	157 Å²	157	129.6 Å²	129.6	73%	0.734	68%	0.682	S	S	*	*	H	α-helix	trans	-95.5	-4.5	178.5	-73.9	178.6	-0.9	0	0	113.4	R367 E368 I369	R367-Q371 WeakPolarHBondContact O-CG 3.29Å; R367-Q371 PolarHBondContact O-N 3.45Å; E368-Q371 PolarHBondContact O-N 3.47Å; I369-Q371 VanDerWaalsContact C-N 3.32Å
372	M	47.8	Very low	48.6	Very low	123 Å²	123	130 Å²	130	61%	0.606	68%	0.679	S	S	*	*	S	Bend	trans	-69.8	132.2	171.8	-76	-166.9	-93.4	0	0	110.3	E368 I369 S374	E368-M372 PolarHBondContact O-N 3.4Å; I369-M372 HydrophobicContact CB-CE 4.18Å; I369-M372 HydrophobicContact CG1-CE 3.92Å; I369-M372 HydrophobicContact CG2-CE 4.26Å; M372-S374 PolarHBondContact O-N 3.45Å; M372-S374 VanDerWaalsContact O-N 3.11Å
373	P	44.2	Very low	47.6	Very low	122 Å²	122	130.4 Å²	130.4	79%	0.792	68%	0.679	S	S	*	*			trans	-57	121.3	172.8	-17.5	28.7	0	0	0	108.4	A375	P373-A375 PolarHBondContact O-N 2.94Å
374	S	43	Very low	46.9	Very low	97 Å²	97	129.3 Å²	129.3	68%	0.678	67%	0.673	S	S	*	*			trans	-61	111.9	173.3	-164.8	0	0	0	0	107.5	M372 R376	M372-S374 PolarHBondContact O-N 3.45Å; M372-S374 VanDerWaalsContact O-N 3.11Å; S374-R376 PolarHBondContact O-N 2.88Å; S374-R376 WeakPolarHBondContact OG-CB 3.11Å
375	A	44	Very low	46.5	Very low	106 Å²	106	127.3 Å²	127.3	88%	0.876	66%	0.664	S	S	*	*			trans	-72.4	32	169.1	0	0	0	0	0	111.5	P373	P373-A375 PolarHBondContact O-N 2.94Å
376	R	41.7	Very low	46.2	Very low	203 Å²	203	132.8 Å²	132.8	77%	0.766	68%	0.677	S	S	*	*	S	Bend	trans	-88.3	116.6	166.8	-165	173	-173	158.3	1.5	104.5	S374	S374-R376 PolarHBondContact O-N 2.88Å; S374-R376 WeakPolarHBondContact OG-CB 3.11Å
377	P	41.3	Very low	46.1	Very low	102 Å²	102	124.8 Å²	124.8	66%	0.662	65%	0.65	S	S	*	*	P	Polyproline II helix	trans	-50.1	139.7	166.2	21.8	-29.8	0	0	0	107.2	A379	P377-A379 PolarHBondContact O-N 3.1Å; P377-A379 VanDerWaalsContact O-N 3.16Å
378	P	40	Very low	46.6	Very low	117 Å²	117	119.8 Å²	119.8	76%	0.76	64%	0.637	S	S	*	*	P	Polyproline II helix	trans	-48.4	132.4	169.6	22.9	-30.8	0	0	0	106.2	E380	P378-E380 PolarHBondContact O-N 2.8Å
379	A	40.8	Very low	47.3	Very low	81 Å²	81	118.1 Å²	118.1	67%	0.669	63%	0.628	S	S	*	*			trans	-53.5	112.9	168	0	0	0	0	0	104.8	P377 D381	P377-A379 PolarHBondContact O-N 3.1Å; P377-A379 VanDerWaalsContact O-N 3.16Å; A379-D381 PolarHBondContact O-N 3Å
380	E	36.8	Very low	48.1	Very low	178 Å²	178	113.6 Å²	113.6	83%	0.832	61%	0.605	S	S	*	*			trans	-51.5	114.8	164.1	-70.7	175.8	160.3	0	0	104.1	P378 D382	P378-E380 PolarHBondContact O-N 2.8Å; E380-D382 PolarHBondContact O-N 3.17Å; E380-D382 VanDerWaalsContact O-N 3.17Å
381	D	35.4	Very low	49.2	Very low	133 Å²	133	107.7 Å²	107.7	71%	0.711	59%	0.585	S	S	*	*			trans	-52.3	126	-179.1	-77.4	-55.3	0	0	0	107.7	A379 D383	A379-D381 PolarHBondContact O-N 3Å; D381-D383 PolarHBondContact O-N 3.27Å
382	D	39	Very low	50.7	Low	129 Å²	129	101 Å²	101	69%	0.69	55%	0.554	S	S	*	*	G	3₁₀ helix	trans	-61.4	32.9	173.6	-77.7	-42.5	0	0	0	112.6	E380 E384 E385	E380-D382 PolarHBondContact O-N 3.17Å; E380-D382 VanDerWaalsContact O-N 3.17Å; D382-E384 PolarHBondContact O-N 3.22Å; D382-E385 PolarHBondContact O-N 3.04Å
383	D	42.1	Very low	52.5	Low	89 Å²	89	96.4 Å²	96.4	48%	0.476	54%	0.539	S	S	.	.	G	3₁₀ helix	trans	-69.5	-19.7	172.9	-79.4	-37.9	0	0	0	111.6	D381 E385 R386	D381-D383 PolarHBondContact O-N 3.27Å; D383-E385 PolarHBondContact O-N 3.36Å; D383-R386 PolarHBondContact O-N 2.99Å; D383-R386 IonicContact OD1-CZ 3.24Å; D383-R386 IonicContact OD1-NE 3.45Å; D383-R386 IonicContact OD1-NH1 2.75Å; D383-R386 PolarHBondContact OD1-NH1 2.99Å
384	E	40.4	Very low	54.6	Low	120 Å²	120	91.6 Å²	91.6	56%	0.561	51%	0.506	S	S	*	.	G	3₁₀ helix	trans	-66.5	-17.8	173.2	-78.3	-170.1	128	0	0	114.3	Y82 D382	Y82-E384 HydrophobicContact CE1-CG 4.08Å; Y82-E384 WeakPolarHBondContact CE1-OE1 3.36Å; Y82-E384 PolarHBondContact OH-OE1 3.32Å; D382-E384 PolarHBondContact O-N 3.22Å
385	E	46.8	Very low	56.9	Low	106 Å²	106	87 Å²	87	50%	0.495	47%	0.474	S	S	.	.	G	3₁₀ helix	trans	-99.4	-2	179.4	-73.1	-161.6	152.6	0	0	114.7	D382 D383 G387	D382-E385 PolarHBondContact O-N 3.04Å; D383-E385 PolarHBondContact O-N 3.36Å; E385-G387 PolarHBondContact O-N 3.44Å
386	R	50.9	Low	59.3	Low	187 Å²	187	83.1 Å²	83.1	71%	0.706	44%	0.438	S	S	*	.			trans	-74.6	70.2	176.5	-77.5	178.8	170.2	164.7	-3.7	111.4	D383 V388	D383-R386 PolarHBondContact O-N 2.99Å; D383-R386 IonicContact OD1-CZ 3.24Å; D383-R386 IonicContact OD1-NE 3.45Å; D383-R386 IonicContact OD1-NH1 2.75Å; D383-R386 PolarHBondContact OD1-NH1 2.99Å; R386-V388 PolarHBondContact O-N 3.36Å
387	G	56.2	Low	61.7	Low	12 Å²	12	74.8 Å²	74.8	12%	0.124	41%	0.408	C	S	.	.	P	Polyproline II helix	trans	-56.2	135.1	172.5	0	0	0	0	0	111.9	T297 E385 K389	T297-G387 VanDerWaalsContact OG1-CA 3.3Å; T297-G387 WeakPolarHBondContact OG1-CA 3.49Å; E385-G387 PolarHBondContact O-N 3.44Å; G387-K389 PolarHBondContact O-N 3.45Å
388	V	65.4	Low	64.3	Low	53 Å²	53	69.9 Å²	69.9	32%	0.321	38%	0.376	S	S	.	.	P	Polyproline II helix	trans	-67.6	125.6	175.2	-174.6	0	0	0	0	109	H86 L90 S296 R386	H86-V388 HydrophobicContact CB-CG2 4.13Å; L90-V388 HydrophobicContact CD1-CB 3.93Å; L90-V388 HydrophobicContact CD1-CG1 3.64Å; L90-V388 HydrophobicContact CD2-CB 4.26Å; L90-V388 HydrophobicContact CD2-CG1 4.3Å; L90-V388 HydrophobicContact CG-CB 4.35Å; L90-V388 HydrophobicContact CG-CG1 4.46Å; S296-V388 PolarHBondContact OG-N 3.43Å; S296-V388 PolarHBondContact OG-O 3.32Å; R386-V388 PolarHBondContact O-N 3.36Å
389	K	72.2	Confident	67	Low	100 Å²	100	64.4 Å²	64.4	44%	0.435	34%	0.34	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-95.9	133.2	177.9	-69.8	176	-175.8	175.6	0	109	I293 Y294 G387	I293-K389 HydrophobicContact CG2-CB 3.71Å; I293-K389 HydrophobicContact CG2-CD 4.22Å; I293-K389 HydrophobicContact CG2-CG 4.09Å; Y294-K389 WeakPolarHBondContact O-CA 3.32Å; G387-K389 PolarHBondContact O-N 3.45Å
390	L	75.3	Confident	69.5	Low	17 Å²	17	60.5 Å²	60.5	9%	0.089	31%	0.308	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-121.1	142.6	176.8	-164	67.6	0	0	0	109.4	L90 V94 Y294 D394 F395 A443	L90-L390 HydrophobicContact CD2-CB 4.19Å; V94-L390 HydrophobicContact CG2-CD2 4.03Å; Y294-L390 WeakPolarHBondContact CB-O 3.32Å; Y294-L390 PolarHBondContact N-O 3.25Å; Y294-L390 PolarHBondContact O-N 2.98Å; Y294-L390 VanDerWaalsContact O-N 3.09Å; L390-D394 WeakPolarHBondContact CD1-OD2 3.27Å; L390-D394 HydrophobicContact CD2-CB 4.4Å; L390-D394 HydrophobicContact CG-CB 4.22Å; L390-D394 WeakPolarHBondContact CG-OD2 3.3Å; L390-F395 HydrophobicContact CB-CE2 4.06Å; L390-F395 HydrophobicContact CD2-CD2 4.24Å; L390-F395 HydrophobicContact CD2-CE2 3.62Å; L390-F395 HydrophobicContact CD2-CZ 4.23Å; L390-F395 HydrophobicContact CG-CE2 4.05Å; L390-A443 HydrophobicContact CD1-CB 4.14Å
391	G	79.9	Confident	72.3	Confident	29 Å²	29	52 Å²	52	30%	0.299	27%	0.269	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-68.5	138.7	178.9	0	0	0	0	0	110.3	G393 D394 F395	G391-G393 PolarHBondContact O-N 2.9Å; G391-D394 WeakPolarHBondContact O-CB 3.48Å; G391-D394 PolarHBondContact O-N 2.9Å; G391-D394 VanDerWaalsContact O-N 3.11Å; G391-F395 WeakPolarHBondContact O-CD2 3.38Å
392	L	82	Confident	75.2	Confident	16 Å²	16	45.8 Å²	45.8	8%	0.084	24%	0.235	C	C	.	.	H	α-helix	trans	-61.9	-26.2	173.7	-74.7	175	0	0	0	112.5	L232 A291 L292 D394 F395 I396	L232-L392 HydrophobicContact CB-CD2 3.96Å; L232-L392 HydrophobicContact CD2-CD1 4.28Å; L232-L392 HydrophobicContact CD2-CD2 3.93Å; L232-L392 HydrophobicContact CD2-CG 4.45Å; L232-L392 HydrophobicContact CG-CD1 4.2Å; L232-L392 HydrophobicContact CG-CD2 3.96Å; A291-L392 WeakPolarHBondContact O-CD1 3.32Å; L292-L392 PolarHBondContact O-N 3.48Å; L392-D394 VanDerWaalsContact C-N 3.26Å; L392-D394 PolarHBondContact O-N 2.92Å; L392-F395 PolarHBondContact O-N 3.03Å; L392-I396 WeakPolarHBondContact O-CG1 3.17Å; L392-I396 PolarHBondContact O-N 3.27Å
393	G	84.3	Confident	77.8	Confident	28 Å²	28	39.6 Å²	39.6	29%	0.289	20%	0.202	S	C	.	.	H	α-helix	trans	-55.6	-41.6	172.9	0	0	0	0	0	112.4	G391 F395 I396 F397	G391-G393 PolarHBondContact O-N 2.9Å; G393-F395 VanDerWaalsContact C-N 3.34Å; G393-F395 PolarHBondContact O-N 2.85Å; G393-I396 WeakPolarHBondContact O-CB 3.3Å; G393-I396 PolarHBondContact O-N 3.43Å; G393-I396 VanDerWaalsContact O-N 3.1Å; G393-F397 WeakPolarHBondContact O-CD2 3.35Å; G393-F397 PolarHBondContact O-N 3.49Å
394	D	88.3	Confident	80.1	Confident	20 Å²	20	35.9 Å²	35.9	11%	0.107	18%	0.182	C	C	.	.	H	α-helix	trans	-60.6	-45.6	-178.3	-57.6	-16.9	0	0	0	110.6	L390 G391 L392 I396 F397 Y398	L390-D394 WeakPolarHBondContact CD1-OD2 3.27Å; L390-D394 HydrophobicContact CD2-CB 4.4Å; L390-D394 HydrophobicContact CG-CB 4.22Å; L390-D394 WeakPolarHBondContact CG-OD2 3.3Å; G391-D394 WeakPolarHBondContact O-CB 3.48Å; G391-D394 PolarHBondContact O-N 2.9Å; G391-D394 VanDerWaalsContact O-N 3.11Å; L392-D394 VanDerWaalsContact C-N 3.26Å; L392-D394 PolarHBondContact O-N 2.92Å; D394-I396 VanDerWaalsContact C-N 3.32Å; D394-I396 PolarHBondContact O-N 3.31Å; D394-F397 PolarHBondContact O-N 3.43Å; D394-Y398 HydrophobicContact CB-CD2 4.32Å; D394-Y398 HydrophobicContact CB-CE2 3.71Å; D394-Y398 WeakPolarHBondContact O-CB 3.43Å; D394-Y398 WeakPolarHBondContact O-CD2 3.26Å; D394-Y398 PolarHBondContact O-N 2.96Å
395	F	91.9	Very high	82.6	Confident	1 Å²	1	30.1 Å²	30.1	0%	0.004	16%	0.155	C	C	.	.	H	α-helix	trans	-58	-45.3	175.3	-70.7	-111.2	0	0	0	111.6	P93 V94 C97 Y294 L390 G391 L392 G393 S399	P93-F395 HydrophobicContact CB-CE1 3.95Å; P93-F395 HydrophobicContact CB-CZ 4.38Å; P93-F395 HydrophobicContact CG-CE1 4.29Å; P93-F395 HydrophobicContact CG-CZ 4.32Å; V94-F395 HydrophobicContact CB-CE1 4.31Å; V94-F395 HydrophobicContact CG2-CD1 3.98Å; V94-F395 HydrophobicContact CG2-CD2 4.5Å; V94-F395 HydrophobicContact CG2-CE1 3.55Å; V94-F395 HydrophobicContact CG2-CE2 4.14Å; V94-F395 HydrophobicContact CG2-CG 4.43Å; V94-F395 HydrophobicContact CG2-CZ 3.64Å; C97-F395 HydrophobicContact CB-CD1 4.11Å; Y294-F395 HydrophobicContact CD1-CE2 4.33Å; Y294-F395 AromaticContact CD1-CZ 3.86Å; Y294-F395 HydrophobicContact CD1-CZ 3.86Å; Y294-F395 HydrophobicContact CD2-CZ 4.06Å; Y294-F395 HydrophobicContact CE1-CZ 4.33Å; Y294-F395 HydrophobicContact CG-CE2 4.01Å; Y294-F395 AromaticContact CG-CZ 3.72Å; Y294-F395 HydrophobicContact CG-CZ 3.72Å; L390-F395 HydrophobicContact CB-CE2 4.06Å; L390-F395 HydrophobicContact CD2-CD2 4.24Å; L390-F395 HydrophobicContact CD2-CE2 3.62Å; L390-F395 HydrophobicContact CD2-CZ 4.23Å; L390-F395 HydrophobicContact CG-CE2 4.05Å; G391-F395 WeakPolarHBondContact O-CD2 3.38Å; L392-F395 PolarHBondContact O-N 3.03Å; G393-F395 VanDerWaalsContact C-N 3.34Å; G393-F395 PolarHBondContact O-N 2.85Å; F395-S399 VanDerWaalsContact O-CB 3.25Å; F395-S399 WeakPolarHBondContact O-CB 3.34Å; F395-S399 PolarHBondContact O-N 3.38Å; F395-S399 PolarHBondContact O-OG 3.3Å
396	I	93.6	Very high	84.7	Confident	24 Å²	24	25.2 Å²	25.2	12%	0.123	13%	0.132	C	C	.	.	H	α-helix	trans	-62.3	-47.7	-178.9	-64	164.9	0	0	0	110.2	M239 A240 F243 L392 G393 D394 M400	M239-I396 HydrophobicContact CB-CD1 3.89Å; M239-I396 HydrophobicContact CB-CG1 3.98Å; M239-I396 HydrophobicContact CB-CG2 4.13Å; M239-I396 HydrophobicContact CG-CD1 4.32Å; A240-I396 HydrophobicContact CB-CG2 4.45Å; F243-I396 HydrophobicContact CD2-CG2 3.75Å; F243-I396 HydrophobicContact CE2-CG2 3.7Å; L392-I396 WeakPolarHBondContact O-CG1 3.17Å; L392-I396 PolarHBondContact O-N 3.27Å; G393-I396 WeakPolarHBondContact O-CB 3.3Å; G393-I396 PolarHBondContact O-N 3.43Å; G393-I396 VanDerWaalsContact O-N 3.1Å; D394-I396 VanDerWaalsContact C-N 3.32Å; D394-I396 PolarHBondContact O-N 3.31Å; I396-M400 WeakPolarHBondContact O-CB 3.44Å; I396-M400 PolarHBondContact O-N 2.96Å
397	F	94.2	Very high	86.5	Confident	28 Å²	28	17.7 Å²	17.7	12%	0.123	11%	0.11	C	C	.	.	H	α-helix	trans	-72.3	-37.5	-177.1	-66.4	-61.4	0	0	0	112.7	F243 L256 I259 G393 D394 M400 L401 L444 I448	F243-F397 HydrophobicContact CE2-CE1 4.39Å; L256-F397 HydrophobicContact CD2-CB 4.13Å; L256-F397 HydrophobicContact CD2-CD1 3.86Å; L256-F397 HydrophobicContact CD2-CG 4.44Å; I259-F397 HydrophobicContact CD1-CE1 3.57Å; I259-F397 HydrophobicContact CD1-CZ 3.57Å; I259-F397 HydrophobicContact CG2-CD2 4.37Å; I259-F397 HydrophobicContact CG2-CE1 4.25Å; I259-F397 HydrophobicContact CG2-CE2 3.86Å; I259-F397 HydrophobicContact CG2-CZ 3.81Å; G393-F397 WeakPolarHBondContact O-CD2 3.35Å; G393-F397 PolarHBondContact O-N 3.49Å; D394-F397 PolarHBondContact O-N 3.43Å; F397-M400 HydrophobicContact CD1-SD 4.46Å; F397-M400 PolarHBondContact O-N 2.99Å; F397-L401 WeakPolarHBondContact O-CB 3.38Å; F397-L401 PolarHBondContact O-N 3.32Å; F397-L444 HydrophobicContact CB-CD1 4.44Å; F397-L444 HydrophobicContact CD2-CD1 3.47Å; F397-L444 VanDerWaalsContact CD2-CD1 3.47Å; F397-L444 HydrophobicContact CE2-CD1 4.1Å; F397-L444 HydrophobicContact CG-CD1 4.25Å; F397-I448 HydrophobicContact CB-CD1 4.19Å
398	Y	94.9	Very high	87.7	Confident	0 Å²	0	19 Å²	19	0%	0	12%	0.116	C	C	.	.	H	α-helix	trans	-61.5	-48.2	173.1	-63.4	-25.2	0	0	0	111.6	V94 M98 D394 M400 L401 V402 I423 L427 A443 I448	V94-Y398 HydrophobicContact CG1-CD2 3.88Å; M98-Y398 HydrophobicContact CE-CD2 4.41Å; M98-Y398 HydrophobicContact CE-CG 4.14Å; D394-Y398 HydrophobicContact CB-CD2 4.32Å; D394-Y398 HydrophobicContact CB-CE2 3.71Å; D394-Y398 WeakPolarHBondContact O-CB 3.43Å; D394-Y398 WeakPolarHBondContact O-CD2 3.26Å; D394-Y398 PolarHBondContact O-N 2.96Å; Y398-M400 VanDerWaalsContact C-N 3.35Å; Y398-L401 PolarHBondContact O-N 3.5Å; Y398-V402 WeakPolarHBondContact O-CG1 3.17Å; Y398-V402 PolarHBondContact O-N 3.18Å; Y398-I423 HydrophobicContact CD1-CG2 3.68Å; Y398-I423 HydrophobicContact CD2-CG2 4.29Å; Y398-I423 HydrophobicContact CE1-CG2 4.16Å; Y398-I423 HydrophobicContact CG-CG2 3.78Å; Y398-L427 HydrophobicContact CE2-CD1 4.01Å; Y398-A443 PolarHBondContact OH-O 3.49Å; Y398-A443 VanDerWaalsContact OH-O 3.14Å; Y398-I448 HydrophobicContact CD1-CD1 3.91Å; Y398-I448 HydrophobicContact CD1-CG1 4.45Å; Y398-I448 HydrophobicContact CE1-CD1 4.28Å; Y398-I448 HydrophobicContact CE1-CG1 4.33Å
399	S	95.7	Very high	87.8	Confident	1 Å²	1	16.5 Å²	16.5	1%	0.007	10%	0.1	C	C	.	.	H	α-helix	trans	-66.5	-34.6	176.8	-72.3	0	0	0	0	112.9	C97 M98 F395 V402 G403	C97-S399 PolarHBondContact SG-OG 3.25Å; M98-S399 PolarHBondContact N-OG 3.31Å; F395-S399 VanDerWaalsContact O-CB 3.25Å; F395-S399 WeakPolarHBondContact O-CB 3.34Å; F395-S399 PolarHBondContact O-N 3.38Å; F395-S399 PolarHBondContact O-OG 3.3Å; S399-V402 WeakPolarHBondContact O-CG1 3.26Å; S399-G403 WeakPolarHBondContact O-CA 3.45Å; S399-G403 PolarHBondContact O-N 2.88Å
400	M	94.9	Very high	87.2	Confident	0 Å²	0	15.3 Å²	15.3	0%	0	11%	0.105	C	C	.	.	H	α-helix	trans	-64.9	-45.2	175.1	178.6	-177.1	167	0	0	111.5	A240 F243 I244 L247 A252 L256 I396 F397 Y398 G403 K404	A240-M400 HydrophobicContact CB-CB 4.44Å; F243-M400 HydrophobicContact CB-CE 4.29Å; F243-M400 HydrophobicContact CB-CG 4.22Å; F243-M400 HydrophobicContact CB-SD 3.71Å; F243-M400 HydrophobicContact CD2-SD 3.83Å; F243-M400 HydrophobicContact CG-SD 4.13Å; I244-M400 HydrophobicContact CG1-CG 4.42Å; L247-M400 HydrophobicContact CD1-CE 3.46Å; L247-M400 VanDerWaalsContact CD1-CE 3.46Å; L247-M400 HydrophobicContact CD1-SD 4.39Å; A252-M400 HydrophobicContact CB-CE 3.65Å; L256-M400 HydrophobicContact CD2-CG 4.5Å; L256-M400 HydrophobicContact CD2-SD 4.09Å; L256-M400 HydrophobicContact CG-CE 4.3Å; L256-M400 HydrophobicContact CG-SD 4.47Å; I396-M400 WeakPolarHBondContact O-CB 3.44Å; I396-M400 PolarHBondContact O-N 2.96Å; F397-M400 HydrophobicContact CD1-SD 4.46Å; F397-M400 PolarHBondContact O-N 2.99Å; Y398-M400 VanDerWaalsContact C-N 3.35Å; M400-G403 PolarHBondContact O-N 2.95Å; M400-K404 VanDerWaalsContact O-CB 3.32Å; M400-K404 WeakPolarHBondContact O-CB 3.46Å; M400-K404 WeakPolarHBondContact O-CG 3.43Å; M400-K404 PolarHBondContact O-N 2.88Å
401	L	95	Very high	86.6	Confident	0 Å²	0	16 Å²	16	0%	0	12%	0.116	C	C	.	.	H	α-helix	trans	-61.1	-54.7	179.1	-169.4	165.2	0	0	0	110.8	W253 L256 F397 Y398 G403 K404 A405 C419 I423 I448 L452	W253-L401 HydrophobicContact CZ3-CG 4.21Å; L256-L401 HydrophobicContact CD1-CB 3.97Å; L256-L401 HydrophobicContact CD1-CG 4.16Å; F397-L401 WeakPolarHBondContact O-CB 3.38Å; F397-L401 PolarHBondContact O-N 3.32Å; Y398-L401 PolarHBondContact O-N 3.5Å; L401-G403 VanDerWaalsContact C-N 3.32Å; L401-G403 PolarHBondContact O-N 3.3Å; L401-K404 PolarHBondContact O-N 2.95Å; L401-A405 PolarHBondContact O-N 3.11Å; L401-C419 HydrophobicContact CD2-CB 3.93Å; L401-I423 HydrophobicContact CB-CD1 4.41Å; L401-I423 HydrophobicContact CD1-CD1 4.5Å; L401-I423 HydrophobicContact CD2-CD1 4.21Å; L401-I448 HydrophobicContact CB-CD1 4.47Å; L401-I448 HydrophobicContact CD1-CD1 3.79Å; L401-I448 HydrophobicContact CD1-CG2 4.37Å; L401-L452 HydrophobicContact CD1-CD2 4.4Å; L401-L452 HydrophobicContact CD1-CG 4.31Å
402	V	95.2	Very high	86.6	Confident	1 Å²	1	16.7 Å²	16.7	1%	0.006	11%	0.113	C	C	.	.	H	α-helix	trans	-65.6	-35.7	-179.4	70.7	0	0	0	0	112.1	M98 V102 Y398 S399 A405 S406 T416 F420	M98-V402 HydrophobicContact CB-CG1 4Å; M98-V402 HydrophobicContact CG-CG1 3.97Å; V102-V402 HydrophobicContact CG2-CB 4.45Å; V102-V402 HydrophobicContact CG2-CG1 4.01Å; V102-V402 HydrophobicContact CG2-CG2 3.73Å; Y398-V402 WeakPolarHBondContact O-CG1 3.17Å; Y398-V402 PolarHBondContact O-N 3.18Å; S399-V402 WeakPolarHBondContact O-CG1 3.26Å; V402-A405 PolarHBondContact O-N 3.45Å; V402-S406 WeakPolarHBondContact O-CB 3.38Å; V402-S406 PolarHBondContact O-N 2.87Å; V402-T416 HydrophobicContact CG2-CG2 3.69Å; V402-F420 HydrophobicContact CG2-CB 4.3Å
403	G	93.7	Very high	86.9	Confident	0 Å²	0	23.7 Å²	23.7	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-68.5	-40.5	176.6	0	0	0	0	0	112.8	S399 M400 L401 S406 A407	S399-G403 WeakPolarHBondContact O-CA 3.45Å; S399-G403 PolarHBondContact O-N 2.88Å; M400-G403 PolarHBondContact O-N 2.95Å; L401-G403 VanDerWaalsContact C-N 3.32Å; L401-G403 PolarHBondContact O-N 3.3Å; G403-S406 WeakPolarHBondContact O-CB 3.41Å; G403-S406 PolarHBondContact O-N 3.34Å; G403-A407 WeakPolarHBondContact O-CB 3.14Å; G403-A407 PolarHBondContact O-N 3.29Å
404	K	91.9	Very high	87.2	Confident	10 Å²	10	26.1 Å²	26.1	4%	0.043	14%	0.144	C	C	.	.	H	α-helix	trans	-63.8	-41.2	172	-85.3	-59.9	-152.7	-172.1	0	112	I244 L247 A252 W253 M400 L401 S406 A407 T408	I244-K404 HydrophobicContact CG1-CD 4.44Å; I244-K404 HydrophobicContact CG1-CG 4.19Å; I244-K404 HydrophobicContact CG2-CD 4.25Å; I244-K404 PolarHBondContact O-NZ 2.93Å; L247-K404 PolarHBondContact O-NZ 2.59Å; A252-K404 HydrophobicContact CB-CD 4.46Å; A252-K404 VanDerWaalsContact CB-CE 3.42Å; A252-K404 HydrophobicContact CB-CG 4.42Å; W253-K404 HydrophobicContact CH2-CB 4Å; W253-K404 HydrophobicContact CZ2-CB 4.02Å; M400-K404 VanDerWaalsContact O-CB 3.32Å; M400-K404 WeakPolarHBondContact O-CB 3.46Å; M400-K404 WeakPolarHBondContact O-CG 3.43Å; M400-K404 PolarHBondContact O-N 2.88Å; L401-K404 PolarHBondContact O-N 2.95Å; K404-S406 VanDerWaalsContact C-N 3.32Å; K404-S406 PolarHBondContact O-N 3.33Å; K404-A407 PolarHBondContact O-N 2.99Å; K404-T408 WeakPolarHBondContact O-CB 2.86Å; K404-T408 PolarHBondContact O-N 3.39Å; K404-T408 PolarHBondContact O-OG1 2.96Å
405	A	92.3	Very high	87.3	Confident	0 Å²	0	25.1 Å²	25.1	0%	0	14%	0.139	C	C	.	.	H	α-helix	trans	-59.5	-45	174.5	0	0	0	0	0	111.3	L401 V402 A407 A409 C419 Y455	L401-A405 PolarHBondContact O-N 3.11Å; V402-A405 PolarHBondContact O-N 3.45Å; A405-A407 VanDerWaalsContact C-N 3.32Å; A405-A407 PolarHBondContact O-N 3.13Å; A405-A409 VanDerWaalsContact O-CB 3.26Å; A405-A409 WeakPolarHBondContact O-CB 3.49Å; A405-A409 PolarHBondContact O-N 3.49Å; A405-A409 VanDerWaalsContact O-N 3.15Å; A405-C419 HydrophobicContact CB-CB 4.43Å; A405-Y455 HydrophobicContact CB-CD2 3.6Å; A405-Y455 HydrophobicContact CB-CE2 3.79Å
406	S	91.7	Very high	87.4	Confident	2 Å²	2	25.4 Å²	25.4	1%	0.014	14%	0.141	C	C	.	.	H	α-helix	trans	-62.9	-33.9	176.8	179.6	0	0	0	0	114	K106 V402 G403 K404 T416	K106-S406 WeakPolarHBondContact CE-OG 3.15Å; K106-S406 PolarHBondContact NZ-O 3.2Å; K106-S406 VanDerWaalsContact NZ-O 3.08Å; K106-S406 PolarHBondContact NZ-OG 2.9Å; V402-S406 WeakPolarHBondContact O-CB 3.38Å; V402-S406 PolarHBondContact O-N 2.87Å; G403-S406 WeakPolarHBondContact O-CB 3.41Å; G403-S406 PolarHBondContact O-N 3.34Å; K404-S406 VanDerWaalsContact C-N 3.32Å; K404-S406 PolarHBondContact O-N 3.33Å; S406-T416 VanDerWaalsContact CA-OG1 3.29Å; S406-T416 WeakPolarHBondContact CA-OG1 3.43Å
407	A	88.7	Confident	87.4	Confident	30 Å²	30	29.3 Å²	29.3	25%	0.248	16%	0.162	C	C	.	.	H	α-helix	trans	-81	-40.5	-179.6	0	0	0	0	0	113.6	I105 T112 G403 K404 A405	I105-A407 HydrophobicContact CG2-CB 3.83Å; T112-A407 HydrophobicContact CG2-CB 3.93Å; G403-A407 WeakPolarHBondContact O-CB 3.14Å; G403-A407 PolarHBondContact O-N 3.29Å; K404-A407 PolarHBondContact O-N 2.99Å; A405-A407 VanDerWaalsContact C-N 3.32Å; A405-A407 PolarHBondContact O-N 3.13Å
408	T	81.6	Confident	87.4	Confident	39 Å²	39	29 Å²	29	24%	0.239	17%	0.165	C	C	.	.	H	α-helix	trans	-95.9	-33.7	-166.4	-41.9	0	0	0	0	113	E249 K404 S410	E249-T408 HydrophobicContact CG-CG2 4.2Å; K404-T408 WeakPolarHBondContact O-CB 2.86Å; K404-T408 PolarHBondContact O-N 3.39Å; K404-T408 PolarHBondContact O-OG1 2.96Å; T408-S410 PolarHBondContact O-N 3.48Å
409	A	67.3	Low	87.3	Confident	0 Å²	0	29 Å²	29	0%	0	17%	0.165	C	C	.	.	S	Bend	trans	-77	49.8	-177.8	0	0	0	0	0	111.9	A405 G411 D412 T415 Y455	A405-A409 VanDerWaalsContact O-CB 3.26Å; A405-A409 WeakPolarHBondContact O-CB 3.49Å; A405-A409 PolarHBondContact O-N 3.49Å; A405-A409 VanDerWaalsContact O-N 3.15Å; A409-G411 PolarHBondContact O-N 3.02Å; A409-D412 PolarHBondContact O-N 3.22Å; A409-T415 HydrophobicContact CB-CG2 3.92Å; A409-Y455 HydrophobicContact CB-CE2 4.44Å
410	S	58.9	Low	87.3	Confident	75 Å²	75	31 Å²	31	52%	0.524	17%	0.173	S	C	.	.	T	Hydrogen-bonded Turn	trans	53.2	8.1	-178.9	76.8	0	0	0	0	117.3	T408 D412 R463	T408-S410 PolarHBondContact O-N 3.48Å; S410-D412 PolarHBondContact OG-OD2 2.99Å; S410-R463 VanDerWaalsContact CB-NH2 3.3Å; S410-R463 PolarHBondContact OG-NH1 3.17Å; S410-R463 PolarHBondContact OG-NH2 3.34Å
411	G	62.7	Low	87.3	Confident	31 Å²	31	34.1 Å²	34.1	32%	0.32	19%	0.192	S	C	.	.	T	Hydrogen-bonded Turn	trans	96.2	7.8	-173.3	0	0	0	0	0	114.9	K106 A409	K106-G411 VanDerWaalsContact NZ-CA 3.27Å; K106-G411 PolarHBondContact NZ-O 2.99Å; A409-G411 PolarHBondContact O-N 3.02Å
412	D	79.8	Confident	87.3	Confident	44 Å²	44	34.2 Å²	34.2	24%	0.235	19%	0.193	C	C	.	.			trans	-75.1	134.5	-176.4	-72.5	-16.2	0	0	0	113.3	A409 S410 N414 T416 R463	A409-D412 PolarHBondContact O-N 3.22Å; S410-D412 PolarHBondContact OG-OD2 2.99Å; D412-N414 VanDerWaalsContact C-N 3.32Å; D412-T416 PolarHBondContact O-OG1 3.32Å; D412-R463 IonicContact OD2-CZ 3.81Å; D412-R463 IonicContact OD2-NE 2.81Å; D412-R463 PolarHBondContact OD2-NE 2.93Å; D412-R463 IonicContact OD2-NH2 2.79Å; D412-R463 PolarHBondContact OD2-NH2 2.96Å
413	W	87.7	Confident	87.2	Confident	163 Å²	163	34.1 Å²	34.1	62%	0.617	19%	0.192	S	C	*	.	H	α-helix	trans	-71.4	-28.6	177.7	-73.1	97.7	0	0	0	112.1	V102 K106 T416 L417	V102-W413 HydrophobicContact CG1-CH2 4.43Å; V102-W413 HydrophobicContact CG1-CZ3 4.05Å; K106-W413 HydrophobicContact CD-CZ2 4.49Å; K106-W413 HydrophobicContact CG-CH2 4.15Å; K106-W413 HydrophobicContact CG-CZ2 4.12Å; W413-T416 PolarHBondContact O-N 3.13Å; W413-L417 VanDerWaalsContact O-CB 3.28Å; W413-L417 WeakPolarHBondContact O-CB 3.23Å; W413-L417 PolarHBondContact O-N 3.31Å
414	N	90.4	Very high	87.2	Confident	79 Å²	79	35.6 Å²	35.6	42%	0.422	20%	0.2	S	C	.	.	H	α-helix	trans	-60.9	-50.9	-177.1	-66.6	-4.1	0	0	0	111.9	D412 T416 L417 A418	D412-N414 VanDerWaalsContact C-N 3.32Å; N414-T416 VanDerWaalsContact C-N 3.34Å; N414-T416 PolarHBondContact O-N 2.98Å; N414-L417 PolarHBondContact O-N 2.93Å; N414-A418 VanDerWaalsContact O-CB 3.3Å; N414-A418 WeakPolarHBondContact O-CB 3.13Å; N414-A418 PolarHBondContact O-N 3.33Å
415	T	91.8	Very high	87.2	Confident	0 Å²	0	39.2 Å²	39.2	0%	0	22%	0.219	C	C	.	.	H	α-helix	trans	-64.3	-40.3	178.4	-49.6	0	0	0	0	111.7	A409 A418 C419 Y455 T458 D459	A409-T415 HydrophobicContact CB-CG2 3.92Å; T415-A418 PolarHBondContact O-N 3.5Å; T415-C419 WeakPolarHBondContact O-CB 3.4Å; T415-C419 PolarHBondContact O-N 2.97Å; T415-C419 PolarHBondContact O-SG 3.4Å; T415-Y455 HydrophobicContact CG2-CD2 3.58Å; T415-Y455 HydrophobicContact CG2-CE2 3.83Å; T415-T458 HydrophobicContact CG2-CG2 4.43Å; T415-D459 HydrophobicContact CG2-CB 4.35Å
416	T	93.3	Very high	87.2	Confident	6 Å²	6	39.2 Å²	39.2	4%	0.037	22%	0.219	C	C	.	.	H	α-helix	trans	-63.7	-45.9	178.1	-52.1	0	0	0	0	111.3	V102 V402 S406 D412 W413 N414 C419 F420	V102-T416 HydrophobicContact CG1-CG2 3.99Å; V102-T416 HydrophobicContact CG2-CG2 3.9Å; V402-T416 HydrophobicContact CG2-CG2 3.69Å; S406-T416 VanDerWaalsContact CA-OG1 3.29Å; S406-T416 WeakPolarHBondContact CA-OG1 3.43Å; D412-T416 PolarHBondContact O-OG1 3.32Å; W413-T416 PolarHBondContact O-N 3.13Å; N414-T416 VanDerWaalsContact C-N 3.34Å; N414-T416 PolarHBondContact O-N 2.98Å; T416-C419 PolarHBondContact O-N 2.8Å; T416-F420 WeakPolarHBondContact O-CB 3.27Å; T416-F420 PolarHBondContact O-N 2.67Å
417	L	93.3	Very high	87.1	Confident	106 Å²	106	39.2 Å²	39.2	56%	0.555	22%	0.219	S	C	*	.	H	α-helix	trans	-67.8	-41.3	179.7	-174.5	65.9	0	0	0	111.5	W413 N414 C419 F420 V421	W413-L417 VanDerWaalsContact O-CB 3.28Å; W413-L417 WeakPolarHBondContact O-CB 3.23Å; W413-L417 PolarHBondContact O-N 3.31Å; N414-L417 PolarHBondContact O-N 2.93Å; L417-C419 VanDerWaalsContact C-N 3.35Å; L417-C419 PolarHBondContact O-N 3.39Å; L417-F420 HydrophobicContact CD1-CD1 4.4Å; L417-F420 WeakPolarHBondContact O-CB 3.45Å; L417-F420 PolarHBondContact O-N 3.08Å; L417-V421 HydrophobicContact CD1-CG2 4.48Å; L417-V421 WeakPolarHBondContact O-CG2 3.07Å; L417-V421 PolarHBondContact O-N 2.86Å
418	A	94.1	Very high	87	Confident	23 Å²	23	40.6 Å²	40.6	19%	0.19	23%	0.226	C	C	.	.	H	α-helix	trans	-59.5	-45.2	174.6	0	0	0	0	0	111.4	N414 T415 A422 F454 T458	N414-A418 VanDerWaalsContact O-CB 3.3Å; N414-A418 WeakPolarHBondContact O-CB 3.13Å; N414-A418 PolarHBondContact O-N 3.33Å; T415-A418 PolarHBondContact O-N 3.5Å; A418-A422 VanDerWaalsContact O-CB 3.24Å; A418-A422 WeakPolarHBondContact O-CB 3.4Å; A418-A422 PolarHBondContact O-N 3.47Å; A418-F454 HydrophobicContact CB-CD1 4.47Å; A418-T458 HydrophobicContact CB-CG2 4.05Å; A418-T458 WeakPolarHBondContact CB-OG1 3.41Å
419	C	93.6	Very high	87.4	Confident	0 Å²	0	41.6 Å²	41.6	0%	0	23%	0.23	C	C	.	.	H	α-helix	trans	-63.4	-43	175.1	-66.6	0	0	0	0	112.2	L401 A405 T415 T416 L417 A422 I423 Y455	L401-C419 HydrophobicContact CD2-CB 3.93Å; A405-C419 HydrophobicContact CB-CB 4.43Å; T415-C419 WeakPolarHBondContact O-CB 3.4Å; T415-C419 PolarHBondContact O-N 2.97Å; T415-C419 PolarHBondContact O-SG 3.4Å; T416-C419 PolarHBondContact O-N 2.8Å; L417-C419 VanDerWaalsContact C-N 3.35Å; L417-C419 PolarHBondContact O-N 3.39Å; C419-A422 PolarHBondContact O-N 3.2Å; C419-I423 VanDerWaalsContact O-CG1 3.3Å; C419-I423 WeakPolarHBondContact O-CG1 3.22Å; C419-I423 PolarHBondContact O-N 2.77Å; C419-Y455 VanDerWaalsContact SG-CB 3.55Å
420	F	94.9	Very high	88.3	Confident	43 Å²	43	41.7 Å²	41.7	19%	0.189	23%	0.23	C	C	.	.	H	α-helix	trans	-58.7	-51.2	177.6	173.7	-95.9	0	0	0	111.5	T95 M98 V402 T416 L417 A422 I423 L424	T95-F420 HydrophobicContact CG2-CE2 3.85Å; T95-F420 HydrophobicContact CG2-CZ 3.59Å; M98-F420 HydrophobicContact CB-CD2 4.23Å; M98-F420 HydrophobicContact CB-CE2 4.27Å; M98-F420 HydrophobicContact SD-CD2 3.44Å; M98-F420 WeakPolarHBondContact SD-CD2 3.22Å; M98-F420 HydrophobicContact SD-CE2 3.55Å; M98-F420 VanDerWaalsContact SD-CE2 3.55Å; V402-F420 HydrophobicContact CG2-CB 4.3Å; T416-F420 WeakPolarHBondContact O-CB 3.27Å; T416-F420 PolarHBondContact O-N 2.67Å; L417-F420 HydrophobicContact CD1-CD1 4.4Å; L417-F420 WeakPolarHBondContact O-CB 3.45Å; L417-F420 PolarHBondContact O-N 3.08Å; F420-A422 PolarHBondContact O-N 3.35Å; F420-I423 PolarHBondContact O-N 2.84Å; F420-L424 HydrophobicContact CD1-CD1 4.22Å; F420-L424 HydrophobicContact CE1-CD1 3.48Å; F420-L424 VanDerWaalsContact CE1-CD1 3.48Å; F420-L424 HydrophobicContact CE1-CG 4.32Å; F420-L424 HydrophobicContact CE2-CD1 4.32Å; F420-L424 HydrophobicContact CZ-CD1 3.54Å; F420-L424 HydrophobicContact CZ-CG 4.24Å; F420-L424 WeakPolarHBondContact O-CG 3.35Å; F420-L424 PolarHBondContact O-N 3.39Å; F420-L424 VanDerWaalsContact O-N 3.11Å
421	V	94.9	Very high	89.4	Confident	64 Å²	64	39.5 Å²	39.5	39%	0.388	21%	0.212	S	C	.	.	H	α-helix	trans	-63.1	-41.6	177.8	173.6	0	0	0	0	111	L417 I423 L424 I425	L417-V421 HydrophobicContact CD1-CG2 4.48Å; L417-V421 WeakPolarHBondContact O-CG2 3.07Å; L417-V421 PolarHBondContact O-N 2.86Å; V421-I423 PolarHBondContact O-N 3.15Å; V421-L424 PolarHBondContact O-N 3.41Å; V421-I425 HydrophobicContact CG1-CD1 3.64Å; V421-I425 HydrophobicContact CG1-CG1 4.23Å; V421-I425 VanDerWaalsContact O-CG1 3.3Å; V421-I425 WeakPolarHBondContact O-CG1 3.17Å; V421-I425 PolarHBondContact O-N 3.49Å
422	A	95.3	Very high	90.4	Very high	2 Å²	2	42.8 Å²	42.8	2%	0.017	22%	0.222	C	C	.	.	H	α-helix	trans	-61.2	-41.1	178	0	0	0	0	0	112.8	A418 C419 F420 I425 G426 F450 F454	A418-A422 VanDerWaalsContact O-CB 3.24Å; A418-A422 WeakPolarHBondContact O-CB 3.4Å; A418-A422 PolarHBondContact O-N 3.47Å; C419-A422 PolarHBondContact O-N 3.2Å; F420-A422 PolarHBondContact O-N 3.35Å; A422-I425 PolarHBondContact O-N 2.9Å; A422-G426 PolarHBondContact O-N 2.92Å; A422-F450 HydrophobicContact CB-CB 4.36Å; A422-F454 HydrophobicContact CB-CB 3.76Å; A422-F454 HydrophobicContact CB-CD1 4.09Å; A422-F454 HydrophobicContact CB-CD2 3.97Å; A422-F454 HydrophobicContact CB-CG 3.67Å
423	I	94.4	Very high	90.5	Very high	0 Å²	0	42.7 Å²	42.7	0%	0	22%	0.221	C	C	.	.	H	α-helix	trans	-65.8	-43.7	176	-65.5	164.5	0	0	0	110.6	M98 Y398 L401 C419 F420 V421 G426 L427	M98-I423 HydrophobicContact CE-CB 3.95Å; M98-I423 HydrophobicContact CE-CD1 4.05Å; M98-I423 HydrophobicContact CE-CG2 3.36Å; Y398-I423 HydrophobicContact CD1-CG2 3.68Å; Y398-I423 HydrophobicContact CD2-CG2 4.29Å; Y398-I423 HydrophobicContact CE1-CG2 4.16Å; Y398-I423 HydrophobicContact CG-CG2 3.78Å; L401-I423 HydrophobicContact CB-CD1 4.41Å; L401-I423 HydrophobicContact CD1-CD1 4.5Å; L401-I423 HydrophobicContact CD2-CD1 4.21Å; C419-I423 VanDerWaalsContact O-CG1 3.3Å; C419-I423 WeakPolarHBondContact O-CG1 3.22Å; C419-I423 PolarHBondContact O-N 2.77Å; F420-I423 PolarHBondContact O-N 2.84Å; V421-I423 PolarHBondContact O-N 3.15Å; I423-G426 PolarHBondContact O-N 3.32Å; I423-L427 WeakPolarHBondContact O-CB 3.45Å; I423-L427 PolarHBondContact O-N 3.15Å
424	L	92.7	Very high	90	Very high	30 Å²	30	37.3 Å²	37.3	16%	0.157	20%	0.204	C	C	.	.	H	α-helix	trans	-62.7	-42.4	177.6	-70.6	-170.4	0	0	0	112.2	F91 F420 V421 L427 C428	F91-L424 HydrophobicContact CD1-CD1 4.47Å; F91-L424 HydrophobicContact CD1-CD2 3.81Å; F91-L424 HydrophobicContact CE1-CB 3.91Å; F91-L424 HydrophobicContact CE1-CD2 3.85Å; F91-L424 HydrophobicContact CE1-CG 4.29Å; F91-L424 WeakPolarHBondContact CZ-O 3.32Å; F420-L424 HydrophobicContact CD1-CD1 4.22Å; F420-L424 HydrophobicContact CE1-CD1 3.48Å; F420-L424 VanDerWaalsContact CE1-CD1 3.48Å; F420-L424 HydrophobicContact CE1-CG 4.32Å; F420-L424 HydrophobicContact CE2-CD1 4.32Å; F420-L424 HydrophobicContact CZ-CD1 3.54Å; F420-L424 HydrophobicContact CZ-CG 4.24Å; F420-L424 WeakPolarHBondContact O-CG 3.35Å; F420-L424 PolarHBondContact O-N 3.39Å; F420-L424 VanDerWaalsContact O-N 3.11Å; V421-L424 PolarHBondContact O-N 3.41Å; L424-L427 PolarHBondContact O-N 3.46Å; L424-C428 PolarHBondContact O-N 3.02Å
425	I	92.5	Very high	89.3	Confident	86 Å²	86	36.9 Å²	36.9	44%	0.441	21%	0.212	S	C	.	.	H	α-helix	trans	-63.3	-43.9	174.7	-68.2	170	0	0	0	110.6	V421 A422 L427 C428 L429	V421-I425 HydrophobicContact CG1-CD1 3.64Å; V421-I425 HydrophobicContact CG1-CG1 4.23Å; V421-I425 VanDerWaalsContact O-CG1 3.3Å; V421-I425 WeakPolarHBondContact O-CG1 3.17Å; V421-I425 PolarHBondContact O-N 3.49Å; A422-I425 PolarHBondContact O-N 2.9Å; I425-L427 VanDerWaalsContact C-N 3.31Å; I425-L427 PolarHBondContact O-N 2.84Å; I425-C428 WeakPolarHBondContact O-CB 3.36Å; I425-C428 PolarHBondContact O-N 2.91Å; I425-L429 WeakPolarHBondContact O-CB 3.32Å; I425-L429 PolarHBondContact O-N 3.05Å
426	G	91.7	Very high	88.8	Confident	0 Å²	0	42.4 Å²	42.4	0%	0	24%	0.24	C	C	.	.	H	α-helix	trans	-59.6	-41.4	175.4	0	0	0	0	0	112.4	A422 I423 L429 T430	A422-G426 PolarHBondContact O-N 2.92Å; I423-G426 PolarHBondContact O-N 3.32Å; G426-L429 PolarHBondContact O-N 3.42Å; G426-T430 WeakPolarHBondContact O-CG2 3.23Å; G426-T430 PolarHBondContact O-N 3Å
427	L	88.8	Confident	88	Confident	2 Å²	2	48.1 Å²	48.1	1%	0.01	27%	0.265	C	S	.	.	H	α-helix	trans	-65.4	-46.8	176.5	-156.2	158.6	0	0	0	110.6	F91 V94 Y398 I423 L424 I425 L429 T430 L431 S447	F91-L427 HydrophobicContact CD2-CD2 3.93Å; F91-L427 HydrophobicContact CE2-CB 4.29Å; F91-L427 HydrophobicContact CE2-CD2 3.32Å; F91-L427 HydrophobicContact CE2-CG 4.28Å; F91-L427 HydrophobicContact CZ-CB 4.17Å; F91-L427 HydrophobicContact CZ-CD2 4.07Å; V94-L427 HydrophobicContact CG1-CD1 4.43Å; V94-L427 HydrophobicContact CG2-CD1 4.38Å; Y398-L427 HydrophobicContact CE2-CD1 4.01Å; I423-L427 WeakPolarHBondContact O-CB 3.45Å; I423-L427 PolarHBondContact O-N 3.15Å; L424-L427 PolarHBondContact O-N 3.46Å; I425-L427 VanDerWaalsContact C-N 3.31Å; I425-L427 PolarHBondContact O-N 2.84Å; L427-L429 VanDerWaalsContact C-N 3.29Å; L427-L429 PolarHBondContact O-N 3.49Å; L427-T430 WeakPolarHBondContact CA-OG1 3.09Å; L427-T430 PolarHBondContact O-N 3.47Å; L427-T430 PolarHBondContact O-OG1 3.11Å; L427-L431 HydrophobicContact CD2-CD1 3.53Å; L427-L431 HydrophobicContact CD2-CG 3.88Å; L427-L431 WeakPolarHBondContact O-CG 3.44Å; L427-L431 PolarHBondContact O-N 3.47Å; L427-S447 PolarHBondContact N-OG 3.09Å; L427-S447 VanDerWaalsContact N-OG 3.16Å
428	C	88.2	Confident	87	Confident	60 Å²	60	54.2 Å²	54.2	41%	0.405	28%	0.281	S	S	.	.	H	α-helix	trans	-52.2	-48.3	172	-87	0	0	0	0	111.5	F91 L424 I425 T430 L431 L432	F91-C428 HydrophobicContact CZ-CB 4.18Å; F91-C428 WeakPolarHBondContact CZ-SG 3.41Å; L424-C428 PolarHBondContact O-N 3.02Å; I425-C428 WeakPolarHBondContact O-CB 3.36Å; I425-C428 PolarHBondContact O-N 2.91Å; C428-T430 PolarHBondContact O-N 2.92Å; C428-L431 PolarHBondContact O-N 3.35Å; C428-L432 WeakPolarHBondContact O-CB 3.29Å; C428-L432 PolarHBondContact O-N 3.48Å
429	L	88.4	Confident	85.8	Confident	60 Å²	60	60.6 Å²	60.6	31%	0.314	30%	0.304	S	S	.	.	H	α-helix	trans	-64.2	-42.3	-179.2	-167.5	147.5	0	0	0	110.9	I425 G426 L427 L431 L432 L433 I446 F450	I425-L429 WeakPolarHBondContact O-CB 3.32Å; I425-L429 PolarHBondContact O-N 3.05Å; G426-L429 PolarHBondContact O-N 3.42Å; L427-L429 VanDerWaalsContact C-N 3.29Å; L427-L429 PolarHBondContact O-N 3.49Å; L429-L431 PolarHBondContact O-N 3.26Å; L429-L432 PolarHBondContact O-N 3.33Å; L429-L433 HydrophobicContact CD2-CD1 3.55Å; L429-L433 HydrophobicContact CD2-CD2 3.97Å; L429-L433 HydrophobicContact CD2-CG 4.35Å; L429-L433 HydrophobicContact CG-CD1 3.99Å; L429-L433 WeakPolarHBondContact O-CB 3.3Å; L429-L433 VanDerWaalsContact O-CD1 3.26Å; L429-L433 WeakPolarHBondContact O-CD1 3.26Å; L429-L433 PolarHBondContact O-N 3.11Å; L429-I446 HydrophobicContact CD2-CD1 3.99Å; L429-I446 HydrophobicContact CD2-CG2 3.8Å; L429-F450 HydrophobicContact CD1-CE2 4.23Å; L429-F450 HydrophobicContact CD1-CZ 4.46Å
430	T	86.9	Confident	84.5	Confident	2 Å²	2	64.9 Å²	64.9	1%	0.012	34%	0.339	C	S	.	.	H	α-helix	trans	-61.3	-42.4	176.3	62.4	0	0	0	0	112.3	G426 L427 C428 L433 L434 I446	G426-T430 WeakPolarHBondContact O-CG2 3.23Å; G426-T430 PolarHBondContact O-N 3Å; L427-T430 WeakPolarHBondContact CA-OG1 3.09Å; L427-T430 PolarHBondContact O-N 3.47Å; L427-T430 PolarHBondContact O-OG1 3.11Å; C428-T430 PolarHBondContact O-N 2.92Å; T430-L433 PolarHBondContact O-N 3.5Å; T430-L434 VanDerWaalsContact O-CG 3.29Å; T430-L434 WeakPolarHBondContact O-CG 3.38Å; T430-L434 PolarHBondContact O-N 2.91Å; T430-I446 HydrophobicContact CG2-CB 3.58Å; T430-I446 HydrophobicContact CG2-CD1 3.84Å; T430-I446 HydrophobicContact CG2-CG1 4.08Å; T430-I446 HydrophobicContact CG2-CG2 4.01Å
431	L	82.4	Confident	83.3	Confident	29 Å²	29	65.3 Å²	65.3	15%	0.152	34%	0.343	C	S	.	.	H	α-helix	trans	-66.3	-40	177.5	-66.7	179.8	0	0	0	111.7	V87 L90 F91 L427 C428 L429 L434 A435	V87-L431 HydrophobicContact CB-CD1 4.12Å; V87-L431 HydrophobicContact CG1-CD1 3.95Å; V87-L431 HydrophobicContact CG2-CD1 3.71Å; L90-L431 HydrophobicContact CD1-CD1 4.02Å; L90-L431 HydrophobicContact CD1-CD2 3.92Å; F91-L431 HydrophobicContact CE2-CD1 4.18Å; L427-L431 HydrophobicContact CD2-CD1 3.53Å; L427-L431 HydrophobicContact CD2-CG 3.88Å; L427-L431 WeakPolarHBondContact O-CG 3.44Å; L427-L431 PolarHBondContact O-N 3.47Å; C428-L431 PolarHBondContact O-N 3.35Å; L429-L431 PolarHBondContact O-N 3.26Å; L431-L434 HydrophobicContact CD2-CD1 4.16Å; L431-L434 WeakPolarHBondContact O-CB 3.48Å; L431-L434 PolarHBondContact O-N 3.35Å; L431-A435 PolarHBondContact O-N 2.98Å
432	L	83.8	Confident	82.3	Confident	100 Å²	100	62.8 Å²	62.8	52%	0.524	33%	0.328	S	S	.	.	H	α-helix	trans	-64.6	-41.5	175.1	-174.4	149.6	0	0	0	111.6	C428 L429 A435 I436	C428-L432 WeakPolarHBondContact O-CB 3.29Å; C428-L432 PolarHBondContact O-N 3.48Å; L429-L432 PolarHBondContact O-N 3.33Å; L432-A435 WeakPolarHBondContact O-CB 3.25Å; L432-A435 PolarHBondContact O-N 2.94Å; L432-I436 HydrophobicContact CD2-CD1 3.47Å; L432-I436 VanDerWaalsContact CD2-CD1 3.47Å; L432-I436 HydrophobicContact CD2-CG1 4.34Å; L432-I436 HydrophobicContact CG-CD1 4.36Å; L432-I436 WeakPolarHBondContact O-CG1 3.46Å; L432-I436 PolarHBondContact O-N 3.25Å
433	L	82.3	Confident	81.3	Confident	41 Å²	41	63.3 Å²	63.3	22%	0.215	33%	0.333	C	S	.	.	H	α-helix	trans	-65	-38	175	-95.9	64.3	0	0	0	112.3	L429 T430 A435 I436 F437 L441 I446	L429-L433 HydrophobicContact CD2-CD1 3.55Å; L429-L433 HydrophobicContact CD2-CD2 3.97Å; L429-L433 HydrophobicContact CD2-CG 4.35Å; L429-L433 HydrophobicContact CG-CD1 3.99Å; L429-L433 WeakPolarHBondContact O-CB 3.3Å; L429-L433 VanDerWaalsContact O-CD1 3.26Å; L429-L433 WeakPolarHBondContact O-CD1 3.26Å; L429-L433 PolarHBondContact O-N 3.11Å; T430-L433 PolarHBondContact O-N 3.5Å; L433-A435 VanDerWaalsContact C-N 3.33Å; L433-I436 PolarHBondContact O-N 2.89Å; L433-F437 HydrophobicContact CB-CD2 4.22Å; L433-F437 HydrophobicContact CD2-CE2 4.31Å; L433-F437 HydrophobicContact CG-CD2 4.17Å; L433-F437 HydrophobicContact CG-CE2 3.94Å; L433-F437 WeakPolarHBondContact O-CB 3.24Å; L433-F437 WeakPolarHBondContact O-CD2 3.49Å; L433-F437 PolarHBondContact O-N 2.9Å; L433-L441 HydrophobicContact CB-CD1 3.87Å; L433-I446 HydrophobicContact CD2-CD1 3.92Å
434	L	76.5	Confident	80.8	Confident	50 Å²	50	63.6 Å²	63.6	26%	0.262	33%	0.334	S	S	.	.	H	α-helix	trans	-61.3	-42.5	172.8	-74.7	171.9	0	0	0	111.3	T430 L431 R438 K439 L441	T430-L434 VanDerWaalsContact O-CG 3.29Å; T430-L434 WeakPolarHBondContact O-CG 3.38Å; T430-L434 PolarHBondContact O-N 2.91Å; L431-L434 HydrophobicContact CD2-CD1 4.16Å; L431-L434 WeakPolarHBondContact O-CB 3.48Å; L431-L434 PolarHBondContact O-N 3.35Å; L434-R438 PolarHBondContact O-N 2.8Å; L434-R438 VanDerWaalsContact O-N 3.09Å; L434-K439 WeakPolarHBondContact CD2-O 3.32Å; L434-L441 HydrophobicContact CD2-CB 3.7Å; L434-L441 HydrophobicContact CD2-CD1 4.46Å; L434-L441 HydrophobicContact CD2-CG 4.17Å; L434-L441 HydrophobicContact CG-CB 4.38Å
435	A	76.2	Confident	80.5	Confident	71 Å²	71	62.9 Å²	62.9	59%	0.587	33%	0.331	S	S	*	.	H	α-helix	trans	-64	-42.4	178.4	0	0	0	0	0	112.2	L431 L432 L433	L431-A435 PolarHBondContact O-N 2.98Å; L432-A435 WeakPolarHBondContact O-CB 3.25Å; L432-A435 PolarHBondContact O-N 2.94Å; L433-A435 VanDerWaalsContact C-N 3.33Å
436	I	79.9	Confident	80.4	Confident	115 Å²	115	60.9 Å²	60.9	59%	0.59	32%	0.321	S	S	*	.	H	α-helix	trans	-74.4	-49	-179.5	-65	175.3	0	0	0	111.8	L432 L433	L432-I436 HydrophobicContact CD2-CD1 3.47Å; L432-I436 VanDerWaalsContact CD2-CD1 3.47Å; L432-I436 HydrophobicContact CD2-CG1 4.34Å; L432-I436 HydrophobicContact CG-CD1 4.36Å; L432-I436 WeakPolarHBondContact O-CG1 3.46Å; L432-I436 PolarHBondContact O-N 3.25Å; L433-I436 PolarHBondContact O-N 2.89Å
437	F	76.4	Confident	80.4	Confident	127 Å²	127	60.9 Å²	60.9	56%	0.557	32%	0.321	S	S	*	.	H	α-helix	trans	-83.9	-10.9	-171.4	-69.4	-55	0	0	0	114.2	L433 K439 L441	L433-F437 HydrophobicContact CB-CD2 4.22Å; L433-F437 HydrophobicContact CD2-CE2 4.31Å; L433-F437 HydrophobicContact CG-CD2 4.17Å; L433-F437 HydrophobicContact CG-CE2 3.94Å; L433-F437 WeakPolarHBondContact O-CB 3.24Å; L433-F437 WeakPolarHBondContact O-CD2 3.49Å; L433-F437 PolarHBondContact O-N 2.9Å; F437-K439 WeakPolarHBondContact O-CG 3.18Å; F437-K439 PolarHBondContact O-N 3.02Å; F437-L441 HydrophobicContact CD2-CD1 4.2Å
438	R	72.9	Confident	80.6	Confident	234 Å²	234	60.8 Å²	60.8	88%	0.883	32%	0.321	S	S	*	.			trans	44.6	32.4	-176.2	-64.8	-161.9	174.7	-179.3	-0.4	113.5	L434	L434-R438 PolarHBondContact O-N 2.8Å; L434-R438 VanDerWaalsContact O-N 3.09Å
439	K	68.6	Low	80.9	Confident	157 Å²	157	64 Å²	64	68%	0.683	33%	0.328	S	S	*	.	S	Bend	trans	-124.4	141.2	178	-77.5	179.5	179.4	176.2	0	108.4	L434 F437 L441	L434-K439 WeakPolarHBondContact CD2-O 3.32Å; F437-K439 WeakPolarHBondContact O-CG 3.18Å; F437-K439 PolarHBondContact O-N 3.02Å; K439-L441 PolarHBondContact O-N 3.23Å; K439-L441 VanDerWaalsContact O-N 3.12Å
440	A	66.4	Low	81.1	Confident	90 Å²	90	64.1 Å²	64.1	74%	0.744	33%	0.326	S	S	*	.			trans	-64.5	113	172.6	0	0	0	0	0	109.7
441	L	69.3	Low	81.4	Confident	51 Å²	51	64 Å²	64	27%	0.267	33%	0.325	S	S	.	.			trans	-108.4	142.7	174.2	-66.3	168.7	0	0	0	109.2	L433 L434 F437 K439 A443	L433-L441 HydrophobicContact CB-CD1 3.87Å; L434-L441 HydrophobicContact CD2-CB 3.7Å; L434-L441 HydrophobicContact CD2-CD1 4.46Å; L434-L441 HydrophobicContact CD2-CG 4.17Å; L434-L441 HydrophobicContact CG-CB 4.38Å; F437-L441 HydrophobicContact CD2-CD1 4.2Å; K439-L441 PolarHBondContact O-N 3.23Å; K439-L441 VanDerWaalsContact O-N 3.12Å; L441-A443 PolarHBondContact O-N 3.49Å
442	P	74.9	Confident	82	Confident	12 Å²	12	63.6 Å²	63.6	8%	0.078	32%	0.323	C	S	.	.			trans	-65.9	128.5	171.3	21.9	-23.4	0	0	0	109.9	D263 L264 V267 P445	D263-P442 WeakPolarHBondContact OD2-CB 3.48Å; L264-P442 HydrophobicContact CD1-CG 3.83Å; V267-P442 HydrophobicContact CB-CB 4.42Å; V267-P442 HydrophobicContact CB-CG 4.15Å; V267-P442 HydrophobicContact CG1-CG 4.41Å; V267-P442 HydrophobicContact CG2-CB 4.13Å; V267-P442 HydrophobicContact CG2-CG 4.4Å; P442-P445 HydrophobicContact CB-CG 4.05Å; P442-P445 HydrophobicContact CG-CG 3.95Å; P442-P445 WeakPolarHBondContact O-CD 3.33Å
443	A	74.9	Confident	82.5	Confident	13 Å²	13	62 Å²	62	11%	0.107	32%	0.318	C	S	.	.	S	Bend	trans	-80.4	-25	-178	0	0	0	0	0	113	L390 Y398 L441 S447	L390-A443 HydrophobicContact CD1-CB 4.14Å; Y398-A443 PolarHBondContact OH-O 3.49Å; Y398-A443 VanDerWaalsContact OH-O 3.14Å; L441-A443 PolarHBondContact O-N 3.49Å; A443-S447 PolarHBondContact O-OG 2.86Å
444	L	82.5	Confident	83.1	Confident	6 Å²	6	64.3 Å²	64.3	3%	0.031	33%	0.326	C	S	.	.	H	α-helix	trans	-63.9	-48.1	-176.3	-165.8	160.3	0	0	0	114.3	I259 S260 F397 I446 S447 I448	I259-L444 HydrophobicContact CG2-CD1 4.42Å; S260-L444 VanDerWaalsContact CA-CD2 3.5Å; F397-L444 HydrophobicContact CB-CD1 4.44Å; F397-L444 HydrophobicContact CD2-CD1 3.47Å; F397-L444 VanDerWaalsContact CD2-CD1 3.47Å; F397-L444 HydrophobicContact CE2-CD1 4.1Å; F397-L444 HydrophobicContact CG-CD1 4.25Å; L444-I446 PolarHBondContact O-N 2.93Å; L444-S447 PolarHBondContact O-N 3.01Å; L444-I448 HydrophobicContact CD2-CB 4.37Å; L444-I448 HydrophobicContact CD2-CG1 3.66Å; L444-I448 HydrophobicContact CG-CG1 4.11Å; L444-I448 WeakPolarHBondContact O-CB 3.34Å; L444-I448 VanDerWaalsContact O-CG1 3.29Å; L444-I448 WeakPolarHBondContact O-CG1 3.35Å; L444-I448 PolarHBondContact O-N 3.37Å
445	P	87.9	Confident	83.9	Confident	15 Å²	15	62.2 Å²	62.2	10%	0.097	32%	0.315	C	S	.	.	H	α-helix	trans	-66.1	-44.4	-166.3	19.3	-31.2	0	0	0	115.2	L264 P442 F449	L264-P445 HydrophobicContact CB-CB 4.45Å; L264-P445 HydrophobicContact CB-CG 4.3Å; L264-P445 HydrophobicContact CD1-CG 4.06Å; P442-P445 HydrophobicContact CB-CG 4.05Å; P442-P445 HydrophobicContact CG-CG 3.95Å; P442-P445 WeakPolarHBondContact O-CD 3.33Å; P445-F449 VanDerWaalsContact O-CB 3.23Å; P445-F449 WeakPolarHBondContact O-CB 3.3Å; P445-F449 PolarHBondContact O-N 2.92Å
446	I	89.6	Confident	84.6	Confident	44 Å²	44	63.5 Å²	63.5	23%	0.226	31%	0.307	C	S	.	.	H	α-helix	trans	-64.5	-46.5	-177.7	-64.2	-178.3	0	0	0	109.8	L429 T430 L433 L444 F449 F450	L429-I446 HydrophobicContact CD2-CD1 3.99Å; L429-I446 HydrophobicContact CD2-CG2 3.8Å; T430-I446 HydrophobicContact CG2-CB 3.58Å; T430-I446 HydrophobicContact CG2-CD1 3.84Å; T430-I446 HydrophobicContact CG2-CG1 4.08Å; T430-I446 HydrophobicContact CG2-CG2 4.01Å; L433-I446 HydrophobicContact CD2-CD1 3.92Å; L444-I446 PolarHBondContact O-N 2.93Å; I446-F449 PolarHBondContact O-N 3.42Å; I446-F450 HydrophobicContact CG2-CD2 3.8Å; I446-F450 HydrophobicContact CG2-CE2 3.66Å; I446-F450 VanDerWaalsContact O-CD2 3.25Å; I446-F450 WeakPolarHBondContact O-CD2 3.18Å; I446-F450 PolarHBondContact O-N 3Å
447	S	92.6	Very high	85.3	Confident	0 Å²	0	59.8 Å²	59.8	0%	0	29%	0.294	C	S	.	.	H	α-helix	trans	-65.8	-42.3	-178.5	-50.3	0	0	0	0	112.5	L427 A443 L444 G451	L427-S447 PolarHBondContact N-OG 3.09Å; L427-S447 VanDerWaalsContact N-OG 3.16Å; A443-S447 PolarHBondContact O-OG 2.86Å; L444-S447 PolarHBondContact O-N 3.01Å; S447-G451 PolarHBondContact O-N 2.96Å
448	I	92.8	Very high	86	Confident	0 Å²	0	54.2 Å²	54.2	0%	0	27%	0.27	C	S	.	.	H	α-helix	trans	-67.7	-40.2	175.5	-67.2	-63.1	0	0	0	111.3	L256 F397 Y398 L401 L444 G451 L452	L256-I448 HydrophobicContact CB-CG2 4.26Å; L256-I448 HydrophobicContact CD2-CD1 4.38Å; F397-I448 HydrophobicContact CB-CD1 4.19Å; Y398-I448 HydrophobicContact CD1-CD1 3.91Å; Y398-I448 HydrophobicContact CD1-CG1 4.45Å; Y398-I448 HydrophobicContact CE1-CD1 4.28Å; Y398-I448 HydrophobicContact CE1-CG1 4.33Å; L401-I448 HydrophobicContact CB-CD1 4.47Å; L401-I448 HydrophobicContact CD1-CD1 3.79Å; L401-I448 HydrophobicContact CD1-CG2 4.37Å; L444-I448 HydrophobicContact CD2-CB 4.37Å; L444-I448 HydrophobicContact CD2-CG1 3.66Å; L444-I448 HydrophobicContact CG-CG1 4.11Å; L444-I448 WeakPolarHBondContact O-CB 3.34Å; L444-I448 VanDerWaalsContact O-CG1 3.29Å; L444-I448 WeakPolarHBondContact O-CG1 3.35Å; L444-I448 PolarHBondContact O-N 3.37Å; I448-G451 PolarHBondContact O-N 2.93Å; I448-L452 HydrophobicContact CG2-CD1 3.89Å; I448-L452 HydrophobicContact CG2-CG 4.18Å; I448-L452 WeakPolarHBondContact O-CB 3.44Å; I448-L452 VanDerWaalsContact O-CG 3.31Å; I448-L452 WeakPolarHBondContact O-CG 3.14Å; I448-L452 PolarHBondContact O-N 3.46Å
449	F	93.4	Very high	86.9	Confident	127 Å²	127	45 Å²	45	56%	0.557	24%	0.238	S	C	*	.	H	α-helix	trans	-59.8	-50.6	176.9	176.7	-100.3	0	0	0	111.7	P445 I446 G451 L452 V453	P445-F449 VanDerWaalsContact O-CB 3.23Å; P445-F449 WeakPolarHBondContact O-CB 3.3Å; P445-F449 PolarHBondContact O-N 2.92Å; I446-F449 PolarHBondContact O-N 3.42Å; F449-G451 VanDerWaalsContact C-N 3.34Å; F449-G451 PolarHBondContact O-N 3.41Å; F449-L452 PolarHBondContact O-N 3.42Å; F449-V453 HydrophobicContact CD1-CG2 4.46Å; F449-V453 HydrophobicContact CD2-CG2 4.45Å; F449-V453 HydrophobicContact CE1-CG2 4.07Å; F449-V453 HydrophobicContact CE2-CG2 4.06Å; F449-V453 HydrophobicContact CZ-CG2 3.86Å; F449-V453 WeakPolarHBondContact O-CG2 3.19Å; F449-V453 PolarHBondContact O-N 2.76Å
450	F	93.9	Very high	87.9	Confident	62 Å²	62	42.4 Å²	42.4	27%	0.272	23%	0.232	S	C	.	.	H	α-helix	trans	-60	-43.8	175	-79.7	-61.7	0	0	0	111.9	A422 L429 I446 L452 V453 F454	A422-F450 HydrophobicContact CB-CB 4.36Å; L429-F450 HydrophobicContact CD1-CE2 4.23Å; L429-F450 HydrophobicContact CD1-CZ 4.46Å; I446-F450 HydrophobicContact CG2-CD2 3.8Å; I446-F450 HydrophobicContact CG2-CE2 3.66Å; I446-F450 VanDerWaalsContact O-CD2 3.25Å; I446-F450 WeakPolarHBondContact O-CD2 3.18Å; I446-F450 PolarHBondContact O-N 3Å; F450-L452 PolarHBondContact O-N 3.43Å; F450-V453 PolarHBondContact O-N 3.23Å; F450-F454 WeakPolarHBondContact O-CB 3.44Å; F450-F454 WeakPolarHBondContact O-CD2 3.35Å; F450-F454 PolarHBondContact O-N 2.99Å
451	G	93.3	Very high	89.1	Confident	0 Å²	0	44.1 Å²	44.1	0%	0	23%	0.228	C	C	.	.	H	α-helix	trans	-58.3	-44	176.8	0	0	0	0	0	113.2	S447 I448 F449 Y455	S447-G451 PolarHBondContact O-N 2.96Å; I448-G451 PolarHBondContact O-N 2.93Å; F449-G451 VanDerWaalsContact C-N 3.34Å; F449-G451 PolarHBondContact O-N 3.41Å; G451-Y455 VanDerWaalsContact O-CB 3.26Å; G451-Y455 WeakPolarHBondContact O-CB 3.27Å; G451-Y455 PolarHBondContact O-N 3.05Å
452	L	93.8	Very high	90.2	Very high	20 Å²	20	44.3 Å²	44.3	11%	0.105	23%	0.231	C	C	.	.	H	α-helix	trans	-67.1	-44.6	177.5	-71.2	174.2	0	0	0	112	W253 A257 L401 I448 F449 F450 Y455 F456	W253-L452 HydrophobicContact CE3-CD2 3.42Å; W253-L452 VanDerWaalsContact CE3-CD2 3.42Å; W253-L452 HydrophobicContact CZ3-CD2 3.81Å; A257-L452 HydrophobicContact CB-CD1 4.08Å; L401-L452 HydrophobicContact CD1-CD2 4.4Å; L401-L452 HydrophobicContact CD1-CG 4.31Å; I448-L452 HydrophobicContact CG2-CD1 3.89Å; I448-L452 HydrophobicContact CG2-CG 4.18Å; I448-L452 WeakPolarHBondContact O-CB 3.44Å; I448-L452 VanDerWaalsContact O-CG 3.31Å; I448-L452 WeakPolarHBondContact O-CG 3.14Å; I448-L452 PolarHBondContact O-N 3.46Å; F449-L452 PolarHBondContact O-N 3.42Å; F450-L452 PolarHBondContact O-N 3.43Å; L452-Y455 WeakPolarHBondContact O-CB 3.31Å; L452-Y455 PolarHBondContact O-N 2.63Å; L452-F456 WeakPolarHBondContact O-CD2 3.28Å; L452-F456 PolarHBondContact O-N 2.9Å
453	V	94.7	Very high	90.8	Very high	68 Å²	68	46.3 Å²	46.3	41%	0.412	24%	0.237	S	C	.	.	H	α-helix	trans	-61.2	-47.9	178.3	170.6	0	0	0	0	110.6	F449 F450 F456 A457	F449-V453 HydrophobicContact CD1-CG2 4.46Å; F449-V453 HydrophobicContact CD2-CG2 4.45Å; F449-V453 HydrophobicContact CE1-CG2 4.07Å; F449-V453 HydrophobicContact CE2-CG2 4.06Å; F449-V453 HydrophobicContact CZ-CG2 3.86Å; F449-V453 WeakPolarHBondContact O-CG2 3.19Å; F449-V453 PolarHBondContact O-N 2.76Å; F450-V453 PolarHBondContact O-N 3.23Å; V453-F456 PolarHBondContact O-N 2.74Å; V453-A457 WeakPolarHBondContact O-CB 3.46Å; V453-A457 PolarHBondContact O-N 2.85Å
454	F	93.9	Very high	91.6	Very high	88 Å²	88	49 Å²	49	39%	0.386	25%	0.254	S	S	.	.	H	α-helix	trans	-66.4	-37.8	177.7	-87.7	-113.7	0	0	0	111.9	A418 A422 F450 T458	A418-F454 HydrophobicContact CB-CD1 4.47Å; A422-F454 HydrophobicContact CB-CB 3.76Å; A422-F454 HydrophobicContact CB-CD1 4.09Å; A422-F454 HydrophobicContact CB-CD2 3.97Å; A422-F454 HydrophobicContact CB-CG 3.67Å; F450-F454 WeakPolarHBondContact O-CB 3.44Å; F450-F454 WeakPolarHBondContact O-CD2 3.35Å; F450-F454 PolarHBondContact O-N 2.99Å; F454-T458 WeakPolarHBondContact O-CB 3.2Å; F454-T458 PolarHBondContact O-N 3.26Å; F454-T458 PolarHBondContact O-OG1 3.37Å
455	Y	93.1	Very high	92	Very high	7 Å²	7	54 Å²	54	3%	0.027	28%	0.275	C	S	.	.	H	α-helix	trans	-55.2	-57.6	173.7	174.6	-101	0	0	0	111.4	W253 A405 A409 T415 C419 G451 L452 A457 T458 D459	W253-Y455 HydrophobicContact CD2-CE1 4.37Å; W253-Y455 AromaticContact CE2-CE1 3.69Å; W253-Y455 AromaticContact CE2-CZ 3.94Å; W253-Y455 HydrophobicContact CE3-CD1 4.43Å; W253-Y455 AromaticContact CH2-CD1 3.65Å; W253-Y455 HydrophobicContact CH2-CD1 3.65Å; W253-Y455 AromaticContact CH2-CD2 3.61Å; W253-Y455 HydrophobicContact CH2-CD2 3.61Å; W253-Y455 AromaticContact CH2-CE1 3.65Å; W253-Y455 HydrophobicContact CH2-CE1 3.65Å; W253-Y455 AromaticContact CH2-CE2 3.6Å; W253-Y455 HydrophobicContact CH2-CE2 3.6Å; W253-Y455 AromaticContact CH2-CG 3.64Å; W253-Y455 HydrophobicContact CH2-CG 3.64Å; W253-Y455 AromaticContact CH2-CZ 3.62Å; W253-Y455 AromaticContact CZ2-CD1 3.84Å; W253-Y455 HydrophobicContact CZ2-CD1 3.84Å; W253-Y455 HydrophobicContact CZ2-CD2 4.1Å; W253-Y455 AromaticContact CZ2-CE1 3.32Å; W253-Y455 HydrophobicContact CZ2-CE1 3.32Å; W253-Y455 AromaticContact CZ2-CE2 3.61Å; W253-Y455 HydrophobicContact CZ2-CE2 3.61Å; W253-Y455 HydrophobicContact CZ2-CG 4.2Å; W253-Y455 AromaticContact CZ2-CZ 3.19Å; W253-Y455 WeakPolarHBondContact CZ2-OH 3.3Å; W253-Y455 AromaticContact CZ3-CD1 3.97Å; W253-Y455 HydrophobicContact CZ3-CD1 3.97Å; W253-Y455 HydrophobicContact CZ3-CD2 4.41Å; W253-Y455 HydrophobicContact CZ3-CE1 4.29Å; W253-Y455 HydrophobicContact CZ3-CG 4.04Å; A405-Y455 HydrophobicContact CB-CD2 3.6Å; A405-Y455 HydrophobicContact CB-CE2 3.79Å; A409-Y455 HydrophobicContact CB-CE2 4.44Å; T415-Y455 HydrophobicContact CG2-CD2 3.58Å; T415-Y455 HydrophobicContact CG2-CE2 3.83Å; C419-Y455 VanDerWaalsContact SG-CB 3.55Å; G451-Y455 VanDerWaalsContact O-CB 3.26Å; G451-Y455 WeakPolarHBondContact O-CB 3.27Å; G451-Y455 PolarHBondContact O-N 3.05Å; L452-Y455 WeakPolarHBondContact O-CB 3.31Å; L452-Y455 PolarHBondContact O-N 2.63Å; Y455-A457 PolarHBondContact O-N 3.19Å; Y455-T458 PolarHBondContact O-N 3.46Å; Y455-D459 VanDerWaalsContact O-CB 3.25Å; Y455-D459 WeakPolarHBondContact O-CB 3.17Å; Y455-D459 PolarHBondContact O-N 2.84Å
456	F	92.4	Very high	92.1	Very high	97 Å²	97	56 Å²	56	43%	0.425	28%	0.284	S	S	.	.	H	α-helix	trans	-68.1	-38	-176.9	-72.5	-66.5	0	0	0	112.3	W253 L452 V453 N460	W253-F456 HydrophobicContact CD2-CZ 4.49Å; W253-F456 HydrophobicContact CG-CZ 4.33Å; L452-F456 WeakPolarHBondContact O-CD2 3.28Å; L452-F456 PolarHBondContact O-N 2.9Å; V453-F456 PolarHBondContact O-N 2.74Å; F456-N460 VanDerWaalsContact O-CB 3.32Å; F456-N460 WeakPolarHBondContact O-CB 3.3Å; F456-N460 PolarHBondContact O-N 3.39Å; F456-N460 PolarHBondContact O-ND2 2.82Å
457	A	93.4	Very high	92.1	Very high	37 Å²	37	57.1 Å²	57.1	31%	0.306	29%	0.29	S	S	.	.	H	α-helix	trans	-65.8	-44.5	176.6	0	0	0	0	0	111.7	V453 Y455 L461 V462	V453-A457 WeakPolarHBondContact O-CB 3.46Å; V453-A457 PolarHBondContact O-N 2.85Å; Y455-A457 PolarHBondContact O-N 3.19Å; A457-L461 WeakPolarHBondContact O-CA 3.37Å; A457-L461 VanDerWaalsContact O-CB 3.24Å; A457-L461 WeakPolarHBondContact O-CB 3.37Å; A457-L461 PolarHBondContact O-N 3.31Å; A457-V462 PolarHBondContact O-N 2.89Å
458	T	92.4	Very high	92.1	Very high	11 Å²	11	61.8 Å²	61.8	7%	0.067	31%	0.312	C	S	.	.	I	π-helix	trans	-68.9	-43.2	179.7	-59.5	0	0	0	0	111.2	T415 A418 F454 Y455 V462 R463	T415-T458 HydrophobicContact CG2-CG2 4.43Å; A418-T458 HydrophobicContact CB-CG2 4.05Å; A418-T458 WeakPolarHBondContact CB-OG1 3.41Å; F454-T458 WeakPolarHBondContact O-CB 3.2Å; F454-T458 PolarHBondContact O-N 3.26Å; F454-T458 PolarHBondContact O-OG1 3.37Å; Y455-T458 PolarHBondContact O-N 3.46Å; T458-V462 HydrophobicContact CG2-CB 4.05Å; T458-V462 HydrophobicContact CG2-CG1 4.39Å; T458-V462 PolarHBondContact O-N 2.63Å; T458-R463 WeakPolarHBondContact O-CB 3.46Å; T458-R463 PolarHBondContact O-N 3.28Å
459	D	90.3	Very high	92.1	Very high	40 Å²	40	62.9 Å²	62.9	21%	0.214	32%	0.318	C	S	.	.	I	π-helix	trans	-68.1	-39.4	-179.1	-167.4	51	0	0	0	113	T415 Y455 R463	T415-D459 HydrophobicContact CG2-CB 4.35Å; Y455-D459 VanDerWaalsContact O-CB 3.25Å; Y455-D459 WeakPolarHBondContact O-CB 3.17Å; Y455-D459 PolarHBondContact O-N 2.84Å; D459-R463 IonicContact OD1-NH1 2.63Å
460	N	90.4	Very high	92	Very high	103 Å²	103	60.1 Å²	60.1	55%	0.551	32%	0.318	S	S	*	.	I	π-helix	trans	-92.4	-28	-175.9	-67	-88.6	0	0	0	114.5	F456 P464	F456-N460 VanDerWaalsContact O-CB 3.32Å; F456-N460 WeakPolarHBondContact O-CB 3.3Å; F456-N460 PolarHBondContact O-N 3.39Å; F456-N460 PolarHBondContact O-ND2 2.82Å; N460-P464 WeakPolarHBondContact O-CG 3.48Å
461	L	91.9	Very high	92	Very high	125 Å²	125	63.4 Å²	63.4	65%	0.654	34%	0.338	S	S	*	.	I	π-helix	trans	-113.8	-55.4	-173.9	-55.4	173	0	0	0	112.3	A457 F465	A457-L461 WeakPolarHBondContact O-CA 3.37Å; A457-L461 VanDerWaalsContact O-CB 3.24Å; A457-L461 WeakPolarHBondContact O-CB 3.37Å; A457-L461 PolarHBondContact O-N 3.31Å; L461-F465 WeakPolarHBondContact O-CB 3.49Å
462	V	91.1	Very high	92.1	Very high	55 Å²	55	68.3 Å²	68.3	33%	0.333	36%	0.361	S	S	.	.	I	π-helix	trans	-72.2	-41.7	-171.2	-178.6	0	0	0	0	110.9	A457 T458 F465 M466	A457-V462 PolarHBondContact O-N 2.89Å; T458-V462 HydrophobicContact CG2-CB 4.05Å; T458-V462 HydrophobicContact CG2-CG1 4.39Å; T458-V462 PolarHBondContact O-N 2.63Å; V462-F465 PolarHBondContact O-N 2.86Å; V462-M466 HydrophobicContact CG1-CE 4.18Å; V462-M466 HydrophobicContact CG1-CG 3.75Å; V462-M466 WeakPolarHBondContact O-CB 3.2Å; V462-M466 WeakPolarHBondContact O-CG 3.24Å; V462-M466 PolarHBondContact O-N 3.13Å
463	R	88.6	Confident	92	Very high	55 Å²	55	74 Å²	74	21%	0.208	39%	0.387	C	S	.	.	H	α-helix	trans	-59.6	-57.3	-177.2	-179	179.5	178.2	-153	-16.7	113.6	S410 D412 T458 D459 F465 M466 D467	S410-R463 VanDerWaalsContact CB-NH2 3.3Å; S410-R463 PolarHBondContact OG-NH1 3.17Å; S410-R463 PolarHBondContact OG-NH2 3.34Å; D412-R463 IonicContact OD2-CZ 3.81Å; D412-R463 IonicContact OD2-NE 2.81Å; D412-R463 PolarHBondContact OD2-NE 2.93Å; D412-R463 IonicContact OD2-NH2 2.79Å; D412-R463 PolarHBondContact OD2-NH2 2.96Å; T458-R463 WeakPolarHBondContact O-CB 3.46Å; T458-R463 PolarHBondContact O-N 3.28Å; D459-R463 IonicContact OD1-NH1 2.63Å; R463-F465 PolarHBondContact O-N 3.47Å; R463-M466 PolarHBondContact O-N 2.81Å; R463-M466 VanDerWaalsContact O-N 3.13Å; R463-D467 WeakPolarHBondContact O-CB 3.2Å; R463-D467 VanDerWaalsContact O-CG 3.27Å; R463-D467 PolarHBondContact O-N 3.22Å
464	P	90.8	Very high	92	Very high	70 Å²	70	77.4 Å²	77.4	46%	0.455	40%	0.396	S	S	.	.	H	α-helix	trans	-61.4	-32.3	179.1	24.1	-34.5	0	0	0	112.6	N460 E468	N460-P464 WeakPolarHBondContact O-CG 3.48Å; P464-E468 PolarHBondContact O-N 3.21Å
465	F	91.1	Very high	91.8	Very high	110 Å²	110	82.8 Å²	82.8	48%	0.482	42%	0.416	S	S	.	.	H	α-helix	trans	-66.7	-48.3	174	175.4	-103.4	0	0	0	112	L461 V462 R463 D467 E468 L469 I476	L461-F465 WeakPolarHBondContact O-CB 3.49Å; V462-F465 PolarHBondContact O-N 2.86Å; R463-F465 PolarHBondContact O-N 3.47Å; F465-D467 VanDerWaalsContact C-N 3.33Å; F465-D467 PolarHBondContact O-N 3.37Å; F465-E468 PolarHBondContact O-N 2.81Å; F465-L469 HydrophobicContact CD1-CD1 3.95Å; F465-L469 HydrophobicContact CD2-CD1 3.76Å; F465-L469 HydrophobicContact CE1-CD1 3.65Å; F465-L469 HydrophobicContact CE1-CD2 4.08Å; F465-L469 HydrophobicContact CE2-CD1 3.44Å; F465-L469 VanDerWaalsContact CE2-CD1 3.44Å; F465-L469 HydrophobicContact CG-CD1 4.01Å; F465-L469 HydrophobicContact CZ-CD1 3.39Å; F465-L469 HydrophobicContact CZ-CD2 4.13Å; F465-L469 HydrophobicContact CZ-CG 4.42Å; F465-L469 WeakPolarHBondContact O-CD1 3.35Å; F465-L469 PolarHBondContact O-N 2.86Å; F465-I476 HydrophobicContact CE1-CD1 3.94Å
466	M	90.3	Very high	91.5	Very high	58 Å²	58	91.1 Å²	91.1	29%	0.286	46%	0.458	S	S	.	.	H	α-helix	trans	-65.2	-36.2	178.7	-72.6	-67.3	161.9	0	0	112.4	V462 R463 L469 A470 I476	V462-M466 HydrophobicContact CG1-CE 4.18Å; V462-M466 HydrophobicContact CG1-CG 3.75Å; V462-M466 WeakPolarHBondContact O-CB 3.2Å; V462-M466 WeakPolarHBondContact O-CG 3.24Å; V462-M466 PolarHBondContact O-N 3.13Å; R463-M466 PolarHBondContact O-N 2.81Å; R463-M466 VanDerWaalsContact O-N 3.13Å; M466-L469 PolarHBondContact O-N 3.37Å; M466-A470 VanDerWaalsContact O-CB 3.27Å; M466-A470 WeakPolarHBondContact O-CB 3.41Å; M466-A470 PolarHBondContact O-N 3.03Å; M466-I476 HydrophobicContact CE-CD1 3.83Å; M466-I476 HydrophobicContact CE-CG1 4.48Å
467	D	90.3	Very high	91.5	Very high	66 Å²	66	90.8 Å²	90.8	35%	0.353	46%	0.46	S	S	.	.	H	α-helix	trans	-63.4	-43.2	175.8	-70	-14.1	0	0	0	110.5	R463 F465 A470 L471	R463-D467 WeakPolarHBondContact O-CB 3.2Å; R463-D467 VanDerWaalsContact O-CG 3.27Å; R463-D467 PolarHBondContact O-N 3.22Å; F465-D467 VanDerWaalsContact C-N 3.33Å; F465-D467 PolarHBondContact O-N 3.37Å; D467-A470 PolarHBondContact O-N 2.89Å; D467-L471 WeakPolarHBondContact O-CB 3.27Å; D467-L471 WeakPolarHBondContact O-CG 3.06Å; D467-L471 PolarHBondContact O-N 3.35Å
468	E	91.9	Very high	91.4	Very high	99 Å²	99	93.6 Å²	93.6	46%	0.463	47%	0.468	S	S	.	.	H	α-helix	trans	-64.6	-42.5	175.6	-167	65.4	-162.4	0	0	111.8	P464 F465 A470 L471 H472	P464-E468 PolarHBondContact O-N 3.21Å; F465-E468 PolarHBondContact O-N 2.81Å; E468-A470 PolarHBondContact O-N 3.42Å; E468-L471 PolarHBondContact O-N 3.16Å; E468-H472 PolarHBondContact O-CD2 3.19Å; E468-H472 PolarHBondContact O-N 3.48Å; E468-H472 VanDerWaalsContact O-N 3.16Å; E468-H472 IonicContact OE1-CD2 3.42Å; E468-H472 PolarHBondContact OE1-CD2 3.48Å; E468-H472 IonicContact OE1-NE2 2.81Å; E468-H472 PolarHBondContact OE1-NE2 3.3Å
469	L	92.6	Very high	91.3	Very high	23 Å²	23	98.2 Å²	98.2	12%	0.12	49%	0.49	C	S	.	.	H	α-helix	trans	-60.9	-45	174.8	-92.1	79.2	0	0	0	111.7	F465 M466 L471 H472 Q473 F474 I476	F465-L469 HydrophobicContact CD1-CD1 3.95Å; F465-L469 HydrophobicContact CD2-CD1 3.76Å; F465-L469 HydrophobicContact CE1-CD1 3.65Å; F465-L469 HydrophobicContact CE1-CD2 4.08Å; F465-L469 HydrophobicContact CE2-CD1 3.44Å; F465-L469 VanDerWaalsContact CE2-CD1 3.44Å; F465-L469 HydrophobicContact CG-CD1 4.01Å; F465-L469 HydrophobicContact CZ-CD1 3.39Å; F465-L469 HydrophobicContact CZ-CD2 4.13Å; F465-L469 HydrophobicContact CZ-CG 4.42Å; F465-L469 WeakPolarHBondContact O-CD1 3.35Å; F465-L469 PolarHBondContact O-N 2.86Å; M466-L469 PolarHBondContact O-N 3.37Å; L469-L471 VanDerWaalsContact C-N 3.34Å; L469-L471 PolarHBondContact O-N 2.95Å; L469-H472 CarbonylContact O-C 3.54Å; L469-H472 PolarHBondContact O-N 3.31Å; L469-Q473 PolarHBondContact O-N 3.5Å; L469-F474 HydrophobicContact CG-CB 4.48Å; L469-F474 PolarHBondContact O-N 2.92Å; L469-I476 HydrophobicContact CD2-CB 4.36Å; L469-I476 HydrophobicContact CD2-CD1 4.07Å; L469-I476 HydrophobicContact CD2-CG1 3.86Å; L469-I476 HydrophobicContact CD2-CG2 3.68Å
470	A	91.2	Very high	91.4	Very high	68 Å²	68	101.6 Å²	101.6	56%	0.562	51%	0.507	S	S	*	.	H	α-helix	trans	-65	-37.9	179	0	0	0	0	0	111.9	M466 D467 E468 H472 Q473	M466-A470 VanDerWaalsContact O-CB 3.27Å; M466-A470 WeakPolarHBondContact O-CB 3.41Å; M466-A470 PolarHBondContact O-N 3.03Å; D467-A470 PolarHBondContact O-N 2.89Å; E468-A470 PolarHBondContact O-N 3.42Å; A470-H472 VanDerWaalsContact C-N 3.34Å; A470-H472 PolarHBondContact O-N 3.16Å; A470-Q473 PolarHBondContact O-N 3.35Å; A470-Q473 VanDerWaalsContact O-N 3.16Å
471	L	94.2	Very high	91.4	Very high	131 Å²	131	101.6 Å²	101.6	69%	0.686	50%	0.504	S	S	*	.	H	α-helix	trans	-60.9	-41.3	175.2	-77.2	169.9	0	0	0	112.1	D467 E468 L469 Q473	D467-L471 WeakPolarHBondContact O-CB 3.27Å; D467-L471 WeakPolarHBondContact O-CG 3.06Å; D467-L471 PolarHBondContact O-N 3.35Å; E468-L471 PolarHBondContact O-N 3.16Å; L469-L471 VanDerWaalsContact C-N 3.34Å; L469-L471 PolarHBondContact O-N 2.95Å; L471-Q473 VanDerWaalsContact C-N 3.33Å
472	H	95.3	Very high	91.4	Very high	103 Å²	103	100 Å²	100	48%	0.477	49%	0.494	S	S	.	.	T	Hydrogen-bonded Turn	trans	-87.6	0.8	176.2	-65.4	-72	0	0	0	113.9	E468 L469 A470 F474	E468-H472 PolarHBondContact O-CD2 3.19Å; E468-H472 PolarHBondContact O-N 3.48Å; E468-H472 VanDerWaalsContact O-N 3.16Å; E468-H472 IonicContact OE1-CD2 3.42Å; E468-H472 PolarHBondContact OE1-CD2 3.48Å; E468-H472 IonicContact OE1-NE2 2.81Å; E468-H472 PolarHBondContact OE1-NE2 3.3Å; L469-H472 CarbonylContact O-C 3.54Å; L469-H472 PolarHBondContact O-N 3.31Å; A470-H472 VanDerWaalsContact C-N 3.34Å; A470-H472 PolarHBondContact O-N 3.16Å; H472-F474 HydrophobicContact CB-CD2 3.56Å; H472-F474 HydrophobicContact CB-CE2 3.53Å; H472-F474 HydrophobicContact CB-CG 4.1Å; H472-F474 HydrophobicContact CB-CZ 4.05Å; H472-F474 PolarHBondContact O-N 3.27Å
473	Q	92.8	Very high	91.4	Very high	141 Å²	141	103.2 Å²	103.2	66%	0.659	51%	0.505	S	S	*	.	T	Hydrogen-bonded Turn	trans	54.9	32.4	-174.6	-54.1	-173.6	-49.8	0	0	113.8	L469 A470 L471 Y475	L469-Q473 PolarHBondContact O-N 3.5Å; A470-Q473 PolarHBondContact O-N 3.35Å; A470-Q473 VanDerWaalsContact O-N 3.16Å; L471-Q473 VanDerWaalsContact C-N 3.33Å; Q473-Y475 WeakPolarHBondContact O-CD2 3.25Å; Q473-Y475 VanDerWaalsContact O-CE2 3.25Å; Q473-Y475 WeakPolarHBondContact O-CE2 3.37Å
474	F	93.8	Very high	91.6	Very high	138 Å²	138	106.9 Å²	106.9	61%	0.605	53%	0.528	S	S	*	.			trans	-87.7	130.2	171.6	-61.3	-34.4	0	0	0	109.9	L469 H472	L469-F474 HydrophobicContact CG-CB 4.48Å; L469-F474 PolarHBondContact O-N 2.92Å; H472-F474 HydrophobicContact CB-CD2 3.56Å; H472-F474 HydrophobicContact CB-CE2 3.53Å; H472-F474 HydrophobicContact CB-CG 4.1Å; H472-F474 HydrophobicContact CB-CZ 4.05Å; H472-F474 PolarHBondContact O-N 3.27Å
475	Y	90.4	Very high	91.7	Very high	202 Å²	202	110 Å²	110	79%	0.792	53%	0.534	S	S	*	.			trans	-111.2	139.6	179.8	-56.9	-83.1	0	0	0	109.6	Q473	Q473-Y475 WeakPolarHBondContact O-CD2 3.25Å; Q473-Y475 VanDerWaalsContact O-CE2 3.25Å; Q473-Y475 WeakPolarHBondContact O-CE2 3.37Å
476	I	86.9	Confident	91.8	Very high	181 Å²	181	110 Å²	110	93%	0.928	54%	0.539	S	S	*	.			trans	-121.4	0	177.3	57.4	164.3	0	0	0	112.3	F465 M466 L469	F465-I476 HydrophobicContact CE1-CD1 3.94Å; M466-I476 HydrophobicContact CE-CD1 3.83Å; M466-I476 HydrophobicContact CE-CG1 4.48Å; L469-I476 HydrophobicContact CD2-CB 4.36Å; L469-I476 HydrophobicContact CD2-CD1 4.07Å; L469-I476 HydrophobicContact CD2-CG1 3.86Å; L469-I476 HydrophobicContact CD2-CG2 3.68Å

Retrieved 476 of 476 residues in 1977 ms (Link to these results)

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