A0A096LZ55_POEFO Loading...

Tyrosine-protein kinase

AlphaFold DB , UniProt , Accession A0A096LZ55, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 459 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M56.6Low84.4Confident188 Ų18852.8 Ų52.893%0.92631%0.309SS*.  0123.70-68.8174.6-170.300106.1W3 Y43M1-W3 HydrophobicContact SD-CZ2 4.05Å; M1-Y43 PolarHBondContact O-OH 2.97Å
2N75.1Confident85Confident158 Ų15856.6 Ų56.685%0.84532%0.319SS*.  trans-111.499175.8-74.16000107.3Y43N2-Y43 WeakPolarHBondContact CA-OH 3.34Å
3W86.6Confident85.4Confident18 Ų1855.9 Ų55.97%0.06832%0.319CS..PPolyproline II helixtrans-77.8153.6172.8-64.7-43.6000110.1M1 T7 I33 T36 Y43 V61 E63M1-W3 HydrophobicContact SD-CZ2 4.05Å; W3-T7 HydrophobicContact CB-CG2 4.02Å; W3-T7 HydrophobicContact CG-CG2 3.9Å; W3-I33 HydrophobicContact CB-CG1 4.11Å; W3-I33 HydrophobicContact CE3-CD1 4.02Å; W3-I33 HydrophobicContact CE3-CG1 4.34Å; W3-T36 WeakPolarHBondContact O-CG2 3.28Å; W3-Y43 HydrophobicContact CB-CE1 4.11Å; W3-Y43 HydrophobicContact CD2-CE2 4.36Å; W3-Y43 AromaticContact CE3-CD2 3.73Å; W3-Y43 HydrophobicContact CE3-CD2 3.73Å; W3-Y43 HydrophobicContact CE3-CE1 4.42Å; W3-Y43 AromaticContact CE3-CE2 3.46Å; W3-Y43 HydrophobicContact CE3-CE2 3.46Å; W3-Y43 VanDerWaalsContact CE3-CE2 3.46Å; W3-Y43 HydrophobicContact CE3-CG 4.33Å; W3-Y43 AromaticContact CE3-CZ 3.84Å; W3-Y43 AromaticContact CZ3-CD2 3.94Å; W3-Y43 HydrophobicContact CZ3-CD2 3.94Å; W3-Y43 AromaticContact CZ3-CE2 3.8Å; W3-Y43 HydrophobicContact CZ3-CE2 3.8Å; W3-Y43 PolarHBondContact N-OH 2.84Å; W3-Y43 VanDerWaalsContact N-OH 3.16Å; W3-V61 HydrophobicContact CH2-CG2 3.6Å; W3-V61 HydrophobicContact CZ3-CG2 3.53Å; W3-E63 PolarHBondContact NE1-OE2 3.46Å
4A86.4Confident85.9Confident55 Ų5556.6 Ų56.646%0.45532%0.321SS..PPolyproline II helixtrans-97.3158.3175.900000110G6 T7A4-G6 PolarHBondContact O-N 3.48Å; A4-T7 PolarHBondContact N-OG1 3.18Å; A4-T7 VanDerWaalsContact O-CB 3.31Å; A4-T7 WeakPolarHBondContact O-CB 3.22Å; A4-T7 PolarHBondContact O-N 2.89Å; A4-T7 PolarHBondContact O-OG1 2.71Å
5P87.1Confident86.4Confident84 Ų8454.4 Ų54.455%0.54531%0.308SS..THydrogen-bonded Turntrans-50.9135.6164.9-27.237.3000111V34 T36P5-V34 WeakPolarHBondContact CB-O 3.47Å; P5-T36 HydrophobicContact CG-CG2 4.25Å
6G83.2Confident86.5Confident25 Ų2561.9 Ų61.926%0.25833%0.33SS..THydrogen-bonded Turntrans93.7-22.2-172.200000114.4A4 Q8 I33 Q240A4-G6 PolarHBondContact O-N 3.48Å; G6-Q8 PolarHBondContact O-N 3.49Å; G6-I33 PolarHBondContact N-O 3.07Å; G6-Q240 PolarHBondContact O-NE2 3.22Å; G6-Q240 PolarHBondContact O-OE1 2.81Å
7T88Confident86.4Confident23 Ų2369.8 Ų69.814%0.14136%0.361CS..  trans-55.1127-179.6-64.40000111W3 A4 I33 E63W3-T7 HydrophobicContact CB-CG2 4.02Å; W3-T7 HydrophobicContact CG-CG2 3.9Å; A4-T7 PolarHBondContact N-OG1 3.18Å; A4-T7 VanDerWaalsContact O-CB 3.31Å; A4-T7 WeakPolarHBondContact O-CB 3.22Å; A4-T7 PolarHBondContact O-N 2.89Å; A4-T7 PolarHBondContact O-OG1 2.71Å; T7-I33 WeakPolarHBondContact O-CG1 3.39Å; T7-I33 PolarHBondContact O-N 2.81Å; T7-E63 HydrophobicContact CG2-CG 3.85Å
8Q90.7Very high86.1Confident18 Ų1867.5 Ų67.58%0.08435%0.354CS..EExtended strand (participates in β ladder)trans-86.2139.4172.7-70.2-170.6-800110.5G6 I30 L31 N48 R64G6-Q8 PolarHBondContact O-N 3.49Å; Q8-I30 HydrophobicContact CB-CG2 4.26Å; Q8-I30 HydrophobicContact CG-CG2 4.42Å; Q8-L31 CarbonylContact C-O 3.57Å; Q8-L31 WeakPolarHBondContact CA-O 3.37Å; Q8-N48 PolarHBondContact NE2-ND2 2.98Å; Q8-R64 HydrophobicContact CB-CB 3.98Å; Q8-R64 WeakPolarHBondContact O-CB 3.48Å; Q8-R64 PolarHBondContact O-N 2.95Å
9C91.4Very high86.1Confident0 Ų071.5 Ų71.50%037%0.368CS..EExtended strand (participates in β ladder)trans-128.4151.1177.8-58.50000111I30 L31 V61 R62C9-I30 WeakPolarHBondContact O-CA 3.3Å; C9-L31 PolarHBondContact N-O 3.02Å; C9-L31 PolarHBondContact O-N 2.7Å; C9-V61 HydrophobicContact CB-CB 3.96Å; C9-V61 HydrophobicContact CB-CG2 4.12Å; C9-R62 CarbonylContact C-O 3.53Å; C9-R62 WeakPolarHBondContact CA-O 3.32Å; C9-R62 WeakPolarHBondContact CB-O 3.44Å
10V91.5Very high86.2Confident10 Ų1074.7 Ų74.76%0.06139%0.394CS..EExtended strand (participates in β ladder)trans-105.1128173.5-170.70000109K12 I30 V61 R62 R64V10-K12 PolarHBondContact O-N 2.7Å; V10-I30 HydrophobicContact CB-CD1 4.4Å; V10-I30 HydrophobicContact CG1-CD1 4.32Å; V10-I30 HydrophobicContact CG2-CD1 3.81Å; V10-V61 WeakPolarHBondContact O-CA 3.46Å; V10-R62 HydrophobicContact CB-CG 4.21Å; V10-R62 PolarHBondContact N-O 3.47Å; V10-R62 PolarHBondContact O-N 3.23Å; V10-R64 HydrophobicContact CG2-CB 3.86Å; V10-R64 HydrophobicContact CG2-CG 3.88Å
11A91.9Very high86.2Confident2 Ų273.8 Ų73.82%0.01740%0.402CS..EExtended strand (participates in β ladder)trans-66.5128.1172.900000111.5Y25 H26 G28 D29A11-Y25 HydrophobicContact CB-CD2 3.57Å; A11-Y25 HydrophobicContact CB-CE2 3.97Å; A11-Y25 HydrophobicContact CB-CG 4.44Å; A11-H26 VanDerWaalsContact CB-O 3.27Å; A11-H26 WeakPolarHBondContact CB-O 3.41Å; A11-G28 PolarHBondContact O-N 2.68Å; A11-D29 HydrophobicContact CB-CB 4.5Å; A11-D29 PolarHBondContact N-O 3.15Å
12K91.6Very high87.9Confident98 Ų9866.5 Ų66.543%0.42637%0.366SS..SBendtrans-88.1-20.8179.8-61.9-177.3-63.2-1660112.9V10 K27 S59 N60 V61 R62V10-K12 PolarHBondContact O-N 2.7Å; K12-K27 WeakPolarHBondContact O-CD 3.25Å; K12-K27 WeakPolarHBondContact O-CG 3.39Å; K12-S59 WeakPolarHBondContact CE-O 3.46Å; K12-S59 PolarHBondContact NZ-O 3.38Å; K12-N60 WeakPolarHBondContact CB-O 3.48Å; K12-N60 PolarHBondContact N-O 3.46Å; K12-V61 VanDerWaalsContact CE-O 3.27Å; K12-V61 WeakPolarHBondContact CE-O 3.35Å; K12-V61 PolarHBondContact NZ-O 2.81Å; K12-R62 HydrophobicContact CD-CB 4.28Å; K12-R62 HydrophobicContact CD-CG 4.49Å; K12-R62 HydrophobicContact CG-CG 4.29Å
13C90.7Very high88.8Confident48 Ų4859.2 Ų59.232%0.32433%0.327SS..SBendtrans-146.1169.8-178.554.80000110Y25C13-Y25 WeakPolarHBondContact O-CE2 3.28Å
14D92.1Very high89.1Confident65 Ų6562.6 Ų62.635%0.34835%0.346SS..  trans-81143.8174.3-57.4-9.1000110.8R16 K27D14-R16 HydrophobicContact CB-CG 3.94Å; D14-R16 IonicContact OD2-CZ 3.16Å; D14-R16 IonicContact OD2-NE 2.81Å; D14-R16 PolarHBondContact OD2-NE 2.72Å; D14-R16 IonicContact OD2-NH2 2.71Å; D14-R16 PolarHBondContact OD2-NH2 2.83Å; D14-K27 VanDerWaalsContact OD1-CB 3.25Å; D14-K27 WeakPolarHBondContact OD1-CB 3.49Å; D14-K27 PolarHBondContact OD1-N 3.12Å
15N92.6Very high89.4Confident24 Ų2460.1 Ų60.113%0.12833%0.325CS..BIsolated β-bridgetrans-117.867.8166.3-169.829.6000110.2K17 L23 L24 Y25N15-K17 VanDerWaalsContact C-N 3.31Å; N15-K17 PolarHBondContact O-N 2.77Å; N15-L23 PolarHBondContact ND2-O 3.12Å; N15-L24 VanDerWaalsContact O-CD2 3.22Å; N15-L24 WeakPolarHBondContact O-CD2 3.14Å; N15-Y25 HydrophobicContact CB-CD1 3.93Å; N15-Y25 HydrophobicContact CB-CD2 3.9Å; N15-Y25 HydrophobicContact CB-CE1 3.55Å; N15-Y25 HydrophobicContact CB-CE2 3.54Å; N15-Y25 HydrophobicContact CB-CG 4.09Å; N15-Y25 PolarHBondContact N-O 3.05Å
16R88.4Confident89.6Confident175 Ų17560.7 Ų60.766%0.6632%0.32SS*.THydrogen-bonded Turntrans-77.6-12.8-177.1-60.8-179.7-168-156.60.8114.5D14D14-R16 HydrophobicContact CB-CG 3.94Å; D14-R16 IonicContact OD2-CZ 3.16Å; D14-R16 IonicContact OD2-NE 2.81Å; D14-R16 PolarHBondContact OD2-NE 2.72Å; D14-R16 IonicContact OD2-NH2 2.71Å; D14-R16 PolarHBondContact OD2-NH2 2.83Å
17K84.6Confident89.9Confident195 Ų19566.3 Ų66.385%0.84834%0.337SS*.THydrogen-bonded Turntrans-126.855.3-178.2-64.6-175.2-179.6-178.10109.5N15 K19N15-K17 VanDerWaalsContact C-N 3.31Å; N15-K17 PolarHBondContact O-N 2.77Å; K17-K19 PolarHBondContact O-N 2.81Å
18A80.6Confident89.6Confident29 Ų2967.1 Ų67.124%0.2435%0.35CS..PPolyproline II helixtrans-59.3136.1179.700000110.6E22 L24A18-E22 HydrophobicContact CB-CB 3.9Å; A18-E22 WeakPolarHBondContact CB-O 3.25Å; A18-L24 HydrophobicContact CB-CD2 3.52Å; A18-L24 HydrophobicContact CB-CG 3.91Å
19K87.4Confident89.5Confident143 Ų14366.7 Ų66.762%0.62235%0.349SS*.PPolyproline II helixtrans-69163.8171.1-64.3178.9-178.1178.50109.8K17 G21 E22K17-K19 PolarHBondContact O-N 2.81Å; K19-G21 PolarHBondContact O-N 3.47Å; K19-E22 HydrophobicContact CB-CG 4.21Å; K19-E22 PolarHBondContact N-OE2 2.96Å; K19-E22 WeakPolarHBondContact O-CB 3.48Å; K19-E22 PolarHBondContact O-N 2.96Å
20P86.9Confident89.4Confident136 Ų13668 Ų6888%0.88336%0.355SS*.THydrogen-bonded Turntrans-50.8125.8173.8-27.435.5000111.8E22P20-E22 VanDerWaalsContact C-N 3.32Å
21G87.1Confident89.4Confident55 Ų5567.5 Ų67.557%0.56735%0.352SS*.THydrogen-bonded Turntrans82-2.8-177.400000115.6K19 L55K19-G21 PolarHBondContact O-N 3.47Å; G21-L55 WeakPolarHBondContact O-CB 3.42Å; G21-L55 PolarHBondContact O-N 3.02Å
22E92.8Very high89.4Confident35 Ų3568.1 Ų68.116%0.16436%0.356CS..BIsolated β-bridgetrans-89.7148.5170.2-67.617917600111.1A18 K19 P20 R39 L55A18-E22 HydrophobicContact CB-CB 3.9Å; A18-E22 WeakPolarHBondContact CB-O 3.25Å; K19-E22 HydrophobicContact CB-CG 4.21Å; K19-E22 PolarHBondContact N-OE2 2.96Å; K19-E22 WeakPolarHBondContact O-CB 3.48Å; K19-E22 PolarHBondContact O-N 2.96Å; P20-E22 VanDerWaalsContact C-N 3.32Å; E22-R39 IonicContact OE1-NH2 3.96Å; E22-R39 PolarHBondContact OE1-NH2 3.03Å; E22-L55 VanDerWaalsContact CA-O 3.31Å; E22-L55 WeakPolarHBondContact CA-O 3.43Å; E22-L55 HydrophobicContact CG-CB 4.24Å
23L93.8Very high89.5Confident5 Ų563.5 Ų63.53%0.02634%0.336CS..PPolyproline II helixtrans-82.2134.6-178.6-171.463.7000110.9N15 Y25 L31 H47 E52 L55 I56N15-L23 PolarHBondContact ND2-O 3.12Å; L23-Y25 HydrophobicContact CB-CD1 4.36Å; L23-Y25 HydrophobicContact CG-CD1 4.46Å; L23-Y25 WeakPolarHBondContact O-CD1 3.31Å; L23-Y25 VanDerWaalsContact O-CE1 3.28Å; L23-Y25 WeakPolarHBondContact O-CE1 3.42Å; L23-L31 HydrophobicContact CD2-CD2 3.91Å; L23-H47 HydrophobicContact CD1-CB 4.34Å; L23-H47 HydrophobicContact CD2-CB 4.1Å; L23-E52 HydrophobicContact CD1-CB 3.82Å; L23-E52 WeakPolarHBondContact CD1-O 3.28Å; L23-L55 PolarHBondContact N-O 3.33Å; L23-I56 HydrophobicContact CB-CG2 3.9Å; L23-I56 HydrophobicContact CD2-CG2 3.99Å
24L93.3Very high89.6Confident89 Ų8963.4 Ų63.447%0.46633%0.334SS..PPolyproline II helixtrans-77.8134.8169.2-70.3169.8000109.8N15 A18N15-L24 VanDerWaalsContact O-CD2 3.22Å; N15-L24 WeakPolarHBondContact O-CD2 3.14Å; A18-L24 HydrophobicContact CB-CD2 3.52Å; A18-L24 HydrophobicContact CB-CG 3.91Å
25Y93Very high89.4Confident4 Ų463.1 Ų63.12%0.01633%0.332CS..BIsolated β-bridgetrans-159.8160.6176.453-95.4000111.3A11 C13 N15 L23 L31 I56A11-Y25 HydrophobicContact CB-CD2 3.57Å; A11-Y25 HydrophobicContact CB-CE2 3.97Å; A11-Y25 HydrophobicContact CB-CG 4.44Å; C13-Y25 WeakPolarHBondContact O-CE2 3.28Å; N15-Y25 HydrophobicContact CB-CD1 3.93Å; N15-Y25 HydrophobicContact CB-CD2 3.9Å; N15-Y25 HydrophobicContact CB-CE1 3.55Å; N15-Y25 HydrophobicContact CB-CE2 3.54Å; N15-Y25 HydrophobicContact CB-CG 4.09Å; N15-Y25 PolarHBondContact N-O 3.05Å; L23-Y25 HydrophobicContact CB-CD1 4.36Å; L23-Y25 HydrophobicContact CG-CD1 4.46Å; L23-Y25 WeakPolarHBondContact O-CD1 3.31Å; L23-Y25 VanDerWaalsContact O-CE1 3.28Å; L23-Y25 WeakPolarHBondContact O-CE1 3.42Å; Y25-L31 HydrophobicContact CD1-CD1 3.84Å; Y25-L31 HydrophobicContact CD2-CD1 4.42Å; Y25-L31 HydrophobicContact CE1-CD1 4.19Å; Y25-L31 HydrophobicContact CG-CD1 3.98Å; Y25-I56 HydrophobicContact CD1-CG2 4.36Å; Y25-I56 HydrophobicContact CE1-CB 4.47Å; Y25-I56 HydrophobicContact CE1-CG2 3.91Å
26H90.8Very high89.1Confident96 Ų9664.9 Ų64.944%0.44434%0.344SS..  trans-106.8159.2172.4-57.889.8000110.6A11 G28 D29A11-H26 VanDerWaalsContact CB-O 3.27Å; A11-H26 WeakPolarHBondContact CB-O 3.41Å; H26-G28 PolarHBondContact O-N 3.29Å; H26-D29 WeakPolarHBondContact CA-OD2 3.5Å; H26-D29 WeakPolarHBondContact CB-OD2 3.32Å; H26-D29 IonicContact CG-OD2 3.98Å; H26-D29 PolarHBondContact N-OD2 2.96Å; H26-D29 IonicContact ND1-OD2 3.65Å; H26-D29 VanDerWaalsContact O-CB 3.28Å; H26-D29 WeakPolarHBondContact O-CB 3.33Å; H26-D29 VanDerWaalsContact O-CG 3.31Å; H26-D29 PolarHBondContact O-N 3.34Å
27K88.1Confident88.6Confident142 Ų14261.2 Ų61.262%0.61735%0.345SS*.THydrogen-bonded Turntrans-55.8127.7172.1178.4177.6178.9-173.90109.8K12 D14K12-K27 WeakPolarHBondContact O-CD 3.25Å; K12-K27 WeakPolarHBondContact O-CG 3.39Å; D14-K27 VanDerWaalsContact OD1-CB 3.25Å; D14-K27 WeakPolarHBondContact OD1-CB 3.49Å; D14-K27 PolarHBondContact OD1-N 3.12Å
28G82.3Confident88.4Confident40 Ų4053.9 Ų53.941%0.41232%0.317SS..THydrogen-bonded Turntrans95.6-12.4-17800000114.3A11 H26A11-G28 PolarHBondContact O-N 2.68Å; H26-G28 PolarHBondContact O-N 3.29Å
29D88.1Confident88.6Confident10 Ų1059.2 Ų59.25%0.05333%0.33CS..  trans-63.8145.5177.6-70.1-10.6000111.2A11 H26 L31 H47A11-D29 HydrophobicContact CB-CB 4.5Å; A11-D29 PolarHBondContact N-O 3.15Å; H26-D29 WeakPolarHBondContact CA-OD2 3.5Å; H26-D29 WeakPolarHBondContact CB-OD2 3.32Å; H26-D29 IonicContact CG-OD2 3.98Å; H26-D29 PolarHBondContact N-OD2 2.96Å; H26-D29 IonicContact ND1-OD2 3.65Å; H26-D29 VanDerWaalsContact O-CB 3.28Å; H26-D29 WeakPolarHBondContact O-CB 3.33Å; H26-D29 VanDerWaalsContact O-CG 3.31Å; H26-D29 PolarHBondContact O-N 3.34Å; D29-L31 HydrophobicContact CB-CD2 4.48Å; D29-H47 WeakPolarHBondContact CB-NE2 3.27Å; D29-H47 IonicContact OD2-CE1 2.68Å; D29-H47 IonicContact OD2-NE2 3.94Å; D29-H47 PolarHBondContact OD2-NE2 3.44Å
30I89.7Confident88.4Confident26 Ų2662.5 Ų62.513%0.13335%0.345CS..EExtended strand (participates in β ladder)trans-98.1124.2179.8-50.7-57.4000108.9Q8 C9 V10 N48Q8-I30 HydrophobicContact CB-CG2 4.26Å; Q8-I30 HydrophobicContact CG-CG2 4.42Å; C9-I30 WeakPolarHBondContact O-CA 3.3Å; V10-I30 HydrophobicContact CB-CD1 4.4Å; V10-I30 HydrophobicContact CG1-CD1 4.32Å; V10-I30 HydrophobicContact CG2-CD1 3.81Å; I30-N48 HydrophobicContact CB-CB 4.25Å; I30-N48 HydrophobicContact CG2-CB 4.41Å; I30-N48 VanDerWaalsContact O-CB 3.26Å; I30-N48 WeakPolarHBondContact O-CB 2.98Å; I30-N48 PolarHBondContact O-N 2.68Å; I30-N48 PolarHBondContact O-OD1 3.28Å
31L92.7Very high88.4Confident0 Ų057.5 Ų57.50%032%0.318CS..EExtended strand (participates in β ladder)trans-120.9134.8-177-48.1177.3000108.7Q8 C9 L23 Y25 D29 A45 R46 H47 I56 V61Q8-L31 CarbonylContact C-O 3.57Å; Q8-L31 WeakPolarHBondContact CA-O 3.37Å; C9-L31 PolarHBondContact N-O 3.02Å; C9-L31 PolarHBondContact O-N 2.7Å; L23-L31 HydrophobicContact CD2-CD2 3.91Å; Y25-L31 HydrophobicContact CD1-CD1 3.84Å; Y25-L31 HydrophobicContact CD2-CD1 4.42Å; Y25-L31 HydrophobicContact CE1-CD1 4.19Å; Y25-L31 HydrophobicContact CG-CD1 3.98Å; D29-L31 HydrophobicContact CB-CD2 4.48Å; L31-A45 HydrophobicContact CB-CB 4.35Å; L31-R46 CarbonylContact C-O 3.56Å; L31-R46 WeakPolarHBondContact CA-O 3.19Å; L31-H47 HydrophobicContact CD2-CB 4.22Å; L31-I56 HydrophobicContact CB-CD1 4.43Å; L31-I56 HydrophobicContact CD1-CD1 4.22Å; L31-I56 HydrophobicContact CD1-CG2 3.9Å; L31-V61 HydrophobicContact CD1-CG1 3.97Å
32T91.9Very high88.7Confident16 Ų1656.6 Ų56.610%0.09830%0.298CS..EExtended strand (participates in β ladder)trans-104.4124.3178.2-61.40000109.7V34 A45 R46 N48T32-V34 PolarHBondContact O-N 3.32Å; T32-A45 CarbonylContact O-C 3.46Å; T32-A45 WeakPolarHBondContact O-CA 3.37Å; T32-A45 WeakPolarHBondContact O-CB 3.41Å; T32-R46 PolarHBondContact N-O 2.96Å; T32-R46 PolarHBondContact O-N 3.15Å; T32-N48 WeakPolarHBondContact CB-OD1 3.33Å; T32-N48 PolarHBondContact N-OD1 3.01Å; T32-N48 VanDerWaalsContact N-OD1 3.16Å; T32-N48 VanDerWaalsContact OG1-CG 3.28Å; T32-N48 PolarHBondContact OG1-ND2 3.21Å; T32-N48 VanDerWaalsContact OG1-ND2 3.12Å; T32-N48 PolarHBondContact OG1-OD1 2.81Å
33I92.7Very high88.7Confident1 Ų155.8 Ų55.81%0.00529%0.294CS..EExtended strand (participates in β ladder)trans-62.5125.6174.4-55.3-55.3000108.9W3 G6 T7 T36 Y43 A45 I56W3-I33 HydrophobicContact CB-CG1 4.11Å; W3-I33 HydrophobicContact CE3-CD1 4.02Å; W3-I33 HydrophobicContact CE3-CG1 4.34Å; G6-I33 PolarHBondContact N-O 3.07Å; T7-I33 WeakPolarHBondContact O-CG1 3.39Å; T7-I33 PolarHBondContact O-N 2.81Å; I33-T36 HydrophobicContact CG2-CG2 4.03Å; I33-Y43 HydrophobicContact CD1-CD1 4.26Å; I33-Y43 HydrophobicContact CD1-CG 3.92Å; I33-Y43 HydrophobicContact CG2-CD1 3.8Å; I33-Y43 HydrophobicContact CG2-CG 4.43Å; I33-A45 HydrophobicContact CD1-CB 4.37Å; I33-I56 HydrophobicContact CD1-CD1 3.84Å
34V92.5Very high88.7Confident46 Ų4656.6 Ų56.628%0.27930%0.302SS..EExtended strand (participates in β ladder)trans-102-43.7178.5-179.10000109.9P5 T32 A44 R46P5-V34 WeakPolarHBondContact CB-O 3.47Å; T32-V34 PolarHBondContact O-N 3.32Å; V34-A44 PolarHBondContact N-O 2.92Å; V34-R46 HydrophobicContact CG2-CB 3.79Å
35D88.5Confident88.8Confident58 Ų5852.4 Ų52.431%0.3128%0.279SS..EExtended strand (participates in β ladder)trans-143.6145.7-179.5-176.823.6000111.3S37 A44D35-S37 VanDerWaalsContact CG-OG 3.31Å; D35-S37 WeakPolarHBondContact OD1-CB 3.27Å; D35-S37 PolarHBondContact OD1-N 2.86Å; D35-S37 PolarHBondContact OD1-OG 2.85Å; D35-S37 PolarHBondContact OD2-OG 3.27Å; D35-A44 HydrophobicContact CB-CB 3.98Å; D35-A44 PolarHBondContact N-O 2.84Å; D35-A44 PolarHBondContact O-N 3.04Å; D35-A44 VanDerWaalsContact O-N 3.07Å
36T85.4Confident88.9Confident62 Ų6256.9 Ų56.938%0.3830%0.296SS..  trans-110.2-8.6-177.665.90000111.7W3 P5 I33 T38 Y43W3-T36 WeakPolarHBondContact O-CG2 3.28Å; P5-T36 HydrophobicContact CG-CG2 4.25Å; I33-T36 HydrophobicContact CG2-CG2 4.03Å; T36-T38 PolarHBondContact O-N 2.9Å; T36-Y43 HydrophobicContact CG2-CD1 4.08Å; T36-Y43 HydrophobicContact CG2-CE1 3.96Å
37S79.3Confident89Confident98 Ų9852.8 Ų52.869%0.68528%0.277SS*.  trans-76.227.7-179.183.90000114.2D35D35-S37 VanDerWaalsContact CG-OG 3.31Å; D35-S37 WeakPolarHBondContact OD1-CB 3.27Å; D35-S37 PolarHBondContact OD1-N 2.86Å; D35-S37 PolarHBondContact OD1-OG 2.85Å; D35-S37 PolarHBondContact OD2-OG 3.27Å
38T79.3Confident88.7Confident40 Ų4046.7 Ų46.725%0.24525%0.252CS..SBendtrans-97.6173.2-17750.40000112.7T36 F42 Y43 A44 L55T36-T38 PolarHBondContact O-N 2.9Å; T38-F42 VanDerWaalsContact OG1-C 3.23Å; T38-F42 PolarHBondContact OG1-O 2.81Å; T38-Y43 VanDerWaalsContact OG1-CA 3.3Å; T38-Y43 WeakPolarHBondContact OG1-CA 3.33Å; T38-A44 HydrophobicContact CG2-CB 4.14Å; T38-L55 HydrophobicContact CG2-CD2 3.64Å
39R85.1Confident88.7Confident141 Ų14147.1 Ų47.153%0.53225%0.246SC..SBendtrans-55.1147.5175.368.1-177.5-178.3-163.8-3.8111.7E22 G41 F42E22-R39 IonicContact OE1-NH2 3.96Å; E22-R39 PolarHBondContact OE1-NH2 3.03Å; R39-G41 PolarHBondContact O-N 3.49Å; R39-F42 HydrophobicContact CG-CB 3.9Å; R39-F42 HydrophobicContact CG-CD2 3.78Å; R39-F42 HydrophobicContact CG-CG 4.03Å; R39-F42 PolarHBondContact O-N 3.05Å
40K84.3Confident88.5Confident213 Ų21350.2 Ų50.293%0.92627%0.266SS*.THydrogen-bonded Turntrans-50127.2-177.3-171.6176.1-178.8178.50111.8F42K40-F42 VanDerWaalsContact C-N 3.32Å
41G86.8Confident88.3Confident30 Ų3056.1 Ų56.131%0.30929%0.293SS..THydrogen-bonded Turntrans85.6-3.6178.700000114.9R39 N57 S58R39-G41 PolarHBondContact O-N 3.49Å; G41-N57 PolarHBondContact O-OD1 2.83Å; G41-S58 WeakPolarHBondContact O-CB 3.39Å; G41-S58 PolarHBondContact O-N 2.85Å; G41-S58 PolarHBondContact O-OG 3.43Å
42F91.9Very high88.2Confident36 Ų3661.2 Ų61.216%0.15832%0.317CS..EExtended strand (participates in β ladder)trans-113158.4171.6-73.1-102.2000111T38 R39 K40 L55 I56 N57T38-F42 VanDerWaalsContact OG1-C 3.23Å; T38-F42 PolarHBondContact OG1-O 2.81Å; R39-F42 HydrophobicContact CG-CB 3.9Å; R39-F42 HydrophobicContact CG-CD2 3.78Å; R39-F42 HydrophobicContact CG-CG 4.03Å; R39-F42 PolarHBondContact O-N 3.05Å; K40-F42 VanDerWaalsContact C-N 3.32Å; F42-L55 HydrophobicContact CD1-CB 4.25Å; F42-I56 CarbonylContact C-O 3.59Å; F42-I56 WeakPolarHBondContact CA-O 3.24Å; F42-I56 WeakPolarHBondContact CD1-O 3.37Å; F42-N57 HydrophobicContact CD1-CB 4.34Å; F42-N57 HydrophobicContact CE1-CB 3.94Å; F42-N57 HydrophobicContact CZ-CB 4.15Å
43Y93.4Very high88.3Confident18 Ų1866 Ų667%0.07134%0.338CS..EExtended strand (participates in β ladder)trans-134.5148.2170.7-70.4-89.9000109.2M1 N2 W3 I33 T36 T38 L55 I56M1-Y43 PolarHBondContact O-OH 2.97Å; N2-Y43 WeakPolarHBondContact CA-OH 3.34Å; W3-Y43 HydrophobicContact CB-CE1 4.11Å; W3-Y43 HydrophobicContact CD2-CE2 4.36Å; W3-Y43 AromaticContact CE3-CD2 3.73Å; W3-Y43 HydrophobicContact CE3-CD2 3.73Å; W3-Y43 HydrophobicContact CE3-CE1 4.42Å; W3-Y43 AromaticContact CE3-CE2 3.46Å; W3-Y43 HydrophobicContact CE3-CE2 3.46Å; W3-Y43 VanDerWaalsContact CE3-CE2 3.46Å; W3-Y43 HydrophobicContact CE3-CG 4.33Å; W3-Y43 AromaticContact CE3-CZ 3.84Å; W3-Y43 AromaticContact CZ3-CD2 3.94Å; W3-Y43 HydrophobicContact CZ3-CD2 3.94Å; W3-Y43 AromaticContact CZ3-CE2 3.8Å; W3-Y43 HydrophobicContact CZ3-CE2 3.8Å; W3-Y43 PolarHBondContact N-OH 2.84Å; W3-Y43 VanDerWaalsContact N-OH 3.16Å; I33-Y43 HydrophobicContact CD1-CD1 4.26Å; I33-Y43 HydrophobicContact CD1-CG 3.92Å; I33-Y43 HydrophobicContact CG2-CD1 3.8Å; I33-Y43 HydrophobicContact CG2-CG 4.43Å; T36-Y43 HydrophobicContact CG2-CD1 4.08Å; T36-Y43 HydrophobicContact CG2-CE1 3.96Å; T38-Y43 VanDerWaalsContact OG1-CA 3.3Å; T38-Y43 WeakPolarHBondContact OG1-CA 3.33Å; Y43-L55 CarbonylContact O-C 3.6Å; Y43-L55 WeakPolarHBondContact O-CA 3.42Å; Y43-I56 PolarHBondContact N-O 2.89Å; Y43-I56 PolarHBondContact O-N 3.24Å
44A94.3Very high88.4Confident23 Ų2366.7 Ų66.719%0.1935%0.345CS..EExtended strand (participates in β ladder)trans-78.4129161.700000107.8V34 D35 T38 L55V34-A44 PolarHBondContact N-O 2.92Å; D35-A44 HydrophobicContact CB-CB 3.98Å; D35-A44 PolarHBondContact N-O 2.84Å; D35-A44 PolarHBondContact O-N 3.04Å; D35-A44 VanDerWaalsContact O-N 3.07Å; T38-A44 HydrophobicContact CG2-CB 4.14Å; A44-L55 HydrophobicContact CB-CD2 4.46Å
45A94.9Very high88.5Confident0 Ų066.7 Ų66.70%034%0.343CS..EExtended strand (participates in β ladder)trans-138.5155.9-178.800000111.3L31 T32 I33 E53 G54 I56L31-A45 HydrophobicContact CB-CB 4.35Å; T32-A45 CarbonylContact O-C 3.46Å; T32-A45 WeakPolarHBondContact O-CA 3.37Å; T32-A45 WeakPolarHBondContact O-CB 3.41Å; I33-A45 HydrophobicContact CD1-CB 4.37Å; A45-E53 CarbonylContact O-C 3.6Å; A45-E53 WeakPolarHBondContact O-CA 3.47Å; A45-G54 PolarHBondContact N-O 3Å; A45-G54 PolarHBondContact O-N 3.48Å; A45-G54 VanDerWaalsContact O-O 3.09Å; A45-I56 HydrophobicContact CB-CB 4.46Å; A45-I56 HydrophobicContact CB-CD1 3.49Å; A45-I56 VanDerWaalsContact CB-CD1 3.49Å; A45-I56 HydrophobicContact CB-CG1 3.69Å; A45-I56 HydrophobicContact CB-CG2 3.93Å
46R94.3Very high88.8Confident98 Ų9864 Ų6437%0.3733%0.328SS..EExtended strand (participates in β ladder)trans-105.8136.3172.9-166.4-176.7-43.9141.512.4110.1L31 T32 V34 N48 E51 E52 E53L31-R46 CarbonylContact C-O 3.56Å; L31-R46 WeakPolarHBondContact CA-O 3.19Å; T32-R46 PolarHBondContact N-O 2.96Å; T32-R46 PolarHBondContact O-N 3.15Å; V34-R46 HydrophobicContact CG2-CB 3.79Å; R46-N48 PolarHBondContact O-OD1 3.22Å; R46-E51 VanDerWaalsContact CG-O 3.31Å; R46-E51 WeakPolarHBondContact CG-O 3.16Å; R46-E52 CarbonylContact C-O 3.51Å; R46-E52 VanDerWaalsContact CA-O 3.3Å; R46-E52 WeakPolarHBondContact CA-O 3.42Å; R46-E53 HydrophobicContact CB-CG 3.83Å; R46-E53 HydrophobicContact CG-CG 3.72Å; R46-E53 IonicContact CZ-OE1 3.77Å; R46-E53 IonicContact NE-OE1 3.95Å; R46-E53 PolarHBondContact NE-OE1 3.39Å; R46-E53 IonicContact NH2-OE1 3.78Å; R46-E53 PolarHBondContact NH2-OE1 3.02Å; R46-E53 VanDerWaalsContact NH2-OE1 3.11Å
47H92.4Very high89.2Confident11 Ų1163.1 Ų63.15%0.05132%0.322CS..EExtended strand (participates in β ladder)trans-73.9124.9170.1-165.5-72.4000110.1L23 D29 L31 T49 T50 E51 E52L23-H47 HydrophobicContact CD1-CB 4.34Å; L23-H47 HydrophobicContact CD2-CB 4.1Å; D29-H47 WeakPolarHBondContact CB-NE2 3.27Å; D29-H47 IonicContact OD2-CE1 2.68Å; D29-H47 IonicContact OD2-NE2 3.94Å; D29-H47 PolarHBondContact OD2-NE2 3.44Å; L31-H47 HydrophobicContact CD2-CB 4.22Å; H47-T49 PolarHBondContact ND1-N 3.27Å; H47-T49 PolarHBondContact O-N 3.31Å; H47-T50 VanDerWaalsContact CB-OG1 3.25Å; H47-T50 WeakPolarHBondContact CB-OG1 3.19Å; H47-T50 PolarHBondContact ND1-N 3.28Å; H47-E51 WeakPolarHBondContact O-CA 3.04Å; H47-E51 PolarHBondContact O-N 2.87Å; H47-E52 PolarHBondContact N-O 2.95Å
48N83.6Confident89.7Confident14 Ų1460.1 Ų60.18%0.07530%0.301CS..THydrogen-bonded Turntrans-72.6-12.7-171.1-74.330.7000115.1Q8 I30 T32 R46 R246Q8-N48 PolarHBondContact NE2-ND2 2.98Å; I30-N48 HydrophobicContact CB-CB 4.25Å; I30-N48 HydrophobicContact CG2-CB 4.41Å; I30-N48 VanDerWaalsContact O-CB 3.26Å; I30-N48 WeakPolarHBondContact O-CB 2.98Å; I30-N48 PolarHBondContact O-N 2.68Å; I30-N48 PolarHBondContact O-OD1 3.28Å; T32-N48 WeakPolarHBondContact CB-OD1 3.33Å; T32-N48 PolarHBondContact N-OD1 3.01Å; T32-N48 VanDerWaalsContact N-OD1 3.16Å; T32-N48 VanDerWaalsContact OG1-CG 3.28Å; T32-N48 PolarHBondContact OG1-ND2 3.21Å; T32-N48 VanDerWaalsContact OG1-ND2 3.12Å; T32-N48 PolarHBondContact OG1-OD1 2.81Å; R46-N48 PolarHBondContact O-OD1 3.22Å; N48-R246 PolarHBondContact ND2-NH1 2.88Å
49T80.6Confident90.3Very high48 Ų4861.5 Ų61.529%0.29431%0.312SS..THydrogen-bonded Turntrans-100.5-50.9178.5-51.20000112.5H47 Q213H47-T49 PolarHBondContact ND1-N 3.27Å; H47-T49 PolarHBondContact O-N 3.31Å; T49-Q213 HydrophobicContact CG2-CB 3.75Å; T49-Q213 PolarHBondContact OG1-OE1 3.17Å
50T84.2Confident90.7Very high76 Ų7657.1 Ų57.147%0.46630%0.299SS..THydrogen-bonded Turntrans-88.7-10.7-177.762.50000113.4H47 E52H47-T50 VanDerWaalsContact CB-OG1 3.25Å; H47-T50 WeakPolarHBondContact CB-OG1 3.19Å; H47-T50 PolarHBondContact ND1-N 3.28Å; T50-E52 PolarHBondContact O-N 2.75Å
51E85.3Confident91.1Very high150 Ų15047.1 Ų47.170%0.70126%0.256SS*.  trans61.23.5-174.8-53.1-165153.400115.4R46 H47R46-E51 VanDerWaalsContact CG-O 3.31Å; R46-E51 WeakPolarHBondContact CG-O 3.16Å; H47-E51 WeakPolarHBondContact O-CA 3.04Å; H47-E51 PolarHBondContact O-N 2.87Å
52E91.1Very high91.3Very high107 Ų10749.7 Ų49.750%0.526%0.256SS..  trans-64.4140.4175.5-67.1-176.3162.400111.3L23 R46 H47 T50L23-E52 HydrophobicContact CD1-CB 3.82Å; L23-E52 WeakPolarHBondContact CD1-O 3.28Å; R46-E52 CarbonylContact C-O 3.51Å; R46-E52 VanDerWaalsContact CA-O 3.3Å; R46-E52 WeakPolarHBondContact CA-O 3.42Å; H47-E52 PolarHBondContact N-O 2.95Å; T50-E52 PolarHBondContact O-N 2.75Å
53E94.6Very high91.2Very high116 Ų11652.1 Ų52.154%0.54227%0.268SS..EExtended strand (participates in β ladder)trans-108.4142.7176.2-65.4-166.6167.500111.3A45 R46A45-E53 CarbonylContact O-C 3.6Å; A45-E53 WeakPolarHBondContact O-CA 3.47Å; R46-E53 HydrophobicContact CB-CG 3.83Å; R46-E53 HydrophobicContact CG-CG 3.72Å; R46-E53 IonicContact CZ-OE1 3.77Å; R46-E53 IonicContact NE-OE1 3.95Å; R46-E53 PolarHBondContact NE-OE1 3.39Å; R46-E53 IonicContact NH2-OE1 3.78Å; R46-E53 PolarHBondContact NH2-OE1 3.02Å; R46-E53 VanDerWaalsContact NH2-OE1 3.11Å
54G94.6Very high91Very high15 Ų1551.8 Ų51.816%0.15527%0.267CS..EExtended strand (participates in β ladder)trans-176.3177.3178.500000112.7A45A45-G54 PolarHBondContact N-O 3Å; A45-G54 PolarHBondContact O-N 3.48Å; A45-G54 VanDerWaalsContact O-O 3.09Å
55L94.7Very high90.6Very high46 Ų4655.1 Ų55.124%0.24128%0.278CS..EExtended strand (participates in β ladder)trans-79.5137.3179.3-66.5173.9000111.6G21 E22 L23 T38 F42 Y43 A44G21-L55 WeakPolarHBondContact O-CB 3.42Å; G21-L55 PolarHBondContact O-N 3.02Å; E22-L55 VanDerWaalsContact CA-O 3.31Å; E22-L55 WeakPolarHBondContact CA-O 3.43Å; E22-L55 HydrophobicContact CG-CB 4.24Å; L23-L55 PolarHBondContact N-O 3.33Å; T38-L55 HydrophobicContact CG2-CD2 3.64Å; F42-L55 HydrophobicContact CD1-CB 4.25Å; Y43-L55 CarbonylContact O-C 3.6Å; Y43-L55 WeakPolarHBondContact O-CA 3.42Å; A44-L55 HydrophobicContact CB-CD2 4.46Å
56I94.4Very high90.1Very high1 Ų157 Ų571%0.00529%0.293CS..EExtended strand (participates in β ladder)trans-123.6145.1173.864.3165.2000110.2L23 Y25 L31 I33 F42 Y43 A45 V61L23-I56 HydrophobicContact CB-CG2 3.9Å; L23-I56 HydrophobicContact CD2-CG2 3.99Å; Y25-I56 HydrophobicContact CD1-CG2 4.36Å; Y25-I56 HydrophobicContact CE1-CB 4.47Å; Y25-I56 HydrophobicContact CE1-CG2 3.91Å; L31-I56 HydrophobicContact CB-CD1 4.43Å; L31-I56 HydrophobicContact CD1-CD1 4.22Å; L31-I56 HydrophobicContact CD1-CG2 3.9Å; I33-I56 HydrophobicContact CD1-CD1 3.84Å; F42-I56 CarbonylContact C-O 3.59Å; F42-I56 WeakPolarHBondContact CA-O 3.24Å; F42-I56 WeakPolarHBondContact CD1-O 3.37Å; Y43-I56 PolarHBondContact N-O 2.89Å; Y43-I56 PolarHBondContact O-N 3.24Å; A45-I56 HydrophobicContact CB-CB 4.46Å; A45-I56 HydrophobicContact CB-CD1 3.49Å; A45-I56 VanDerWaalsContact CB-CD1 3.49Å; A45-I56 HydrophobicContact CB-CG1 3.69Å; A45-I56 HydrophobicContact CB-CG2 3.93Å; I56-V61 HydrophobicContact CD1-CG1 4.13Å; I56-V61 HydrophobicContact CD1-CG2 4.05Å
57N93.2Very high89.5Confident45 Ų4552.4 Ų52.424%0.24128%0.276CS..EExtended strand (participates in β ladder)trans-85.2124.5173.2-169.1-28.7000109.7G41 F42 S59 N60G41-N57 PolarHBondContact O-OD1 2.83Å; F42-N57 HydrophobicContact CD1-CB 4.34Å; F42-N57 HydrophobicContact CE1-CB 3.94Å; F42-N57 HydrophobicContact CZ-CB 4.15Å; N57-S59 PolarHBondContact O-N 3.4Å; N57-S59 VanDerWaalsContact O-N 3.15Å; N57-S59 PolarHBondContact OD1-N 2.66Å; N57-S59 PolarHBondContact OD1-OG 2.94Å; N57-N60 PolarHBondContact O-N 2.84Å
58S91.3Very high88.5Confident35 Ų3561.2 Ų61.225%0.24531%0.309CS..G310 helixtrans-56.5-28.9178.762.50000113.8G41 N60 V61G41-S58 WeakPolarHBondContact O-CB 3.39Å; G41-S58 PolarHBondContact O-N 2.85Å; G41-S58 PolarHBondContact O-OG 3.43Å; S58-N60 VanDerWaalsContact C-N 3.28Å; S58-N60 PolarHBondContact O-N 2.92Å; S58-V61 VanDerWaalsContact O-O 3.14Å
59S91.9Very high87.6Confident68 Ų6865.3 Ų65.348%0.47633%0.334SS..G310 helixtrans-73.1-18.7176.967.50000113.5K12 N57K12-S59 WeakPolarHBondContact CE-O 3.46Å; K12-S59 PolarHBondContact NZ-O 3.38Å; N57-S59 PolarHBondContact O-N 3.4Å; N57-S59 VanDerWaalsContact O-N 3.15Å; N57-S59 PolarHBondContact OD1-N 2.66Å; N57-S59 PolarHBondContact OD1-OG 2.94Å
60N93.3Very high86.9Confident49 Ų4965.4 Ų65.426%0.26233%0.333SS..G310 helixtrans-93-8-179.7-69.7-10.4000112.9K12 N57 S58K12-N60 WeakPolarHBondContact CB-O 3.48Å; K12-N60 PolarHBondContact N-O 3.46Å; N57-N60 PolarHBondContact O-N 2.84Å; S58-N60 VanDerWaalsContact C-N 3.28Å; S58-N60 PolarHBondContact O-N 2.92Å
61V92.6Very high86Confident3 Ų368.2 Ų68.22%0.01835%0.352CS..EExtended strand (participates in β ladder)trans-122.7170.8-180-58.90000110.6W3 C9 V10 K12 L31 I56 S58W3-V61 HydrophobicContact CH2-CG2 3.6Å; W3-V61 HydrophobicContact CZ3-CG2 3.53Å; C9-V61 HydrophobicContact CB-CB 3.96Å; C9-V61 HydrophobicContact CB-CG2 4.12Å; V10-V61 WeakPolarHBondContact O-CA 3.46Å; K12-V61 VanDerWaalsContact CE-O 3.27Å; K12-V61 WeakPolarHBondContact CE-O 3.35Å; K12-V61 PolarHBondContact NZ-O 2.81Å; L31-V61 HydrophobicContact CD1-CG1 3.97Å; I56-V61 HydrophobicContact CD1-CG1 4.13Å; I56-V61 HydrophobicContact CD1-CG2 4.05Å; S58-V61 VanDerWaalsContact O-O 3.14Å
62R91.3Very high85.1Confident84 Ų8461.9 Ų61.932%0.31733%0.327SS..EExtended strand (participates in β ladder)trans-142.7153170.263.4-175.1-177.396.6-8.2108.7C9 V10 K12 R64 K181C9-R62 CarbonylContact C-O 3.53Å; C9-R62 WeakPolarHBondContact CA-O 3.32Å; C9-R62 WeakPolarHBondContact CB-O 3.44Å; V10-R62 HydrophobicContact CB-CG 4.21Å; V10-R62 PolarHBondContact N-O 3.47Å; V10-R62 PolarHBondContact O-N 3.23Å; K12-R62 HydrophobicContact CD-CB 4.28Å; K12-R62 HydrophobicContact CD-CG 4.49Å; K12-R62 HydrophobicContact CG-CG 4.29Å; R62-R64 PolarHBondContact O-N 3.01Å; R62-K181 PolarHBondContact NH1-O 3.28Å; R62-K181 PolarHBondContact NH2-O 3.08Å
63E89.4Confident84.2Confident87 Ų8758 Ų5841%0.40731%0.31SS..EExtended strand (participates in β ladder)trans-60.2137.6174.8-170.2167.617400111.1W3 T7 E65W3-E63 PolarHBondContact NE1-OE2 3.46Å; T7-E63 HydrophobicContact CG2-CG 3.85Å; E63-E65 PolarHBondContact O-N 2.92Å
64R89.1Confident83.3Confident12 Ų1253.9 Ų53.95%0.04529%0.294CS..  trans-84.686.9171-167.6-171.5-165-172.45107.7Q8 V10 R62 T182 G183 W184 L248Q8-R64 HydrophobicContact CB-CB 3.98Å; Q8-R64 WeakPolarHBondContact O-CB 3.48Å; Q8-R64 PolarHBondContact O-N 2.95Å; V10-R64 HydrophobicContact CG2-CB 3.86Å; V10-R64 HydrophobicContact CG2-CG 3.88Å; R62-R64 PolarHBondContact O-N 3.01Å; R64-T182 WeakPolarHBondContact CG-O 3.48Å; R64-G183 PolarHBondContact NE-O 3.27Å; R64-G183 PolarHBondContact NH2-O 2.89Å; R64-W184 HydrophobicContact CG-CZ2 4.1Å; R64-L248 PolarHBondContact NH1-O 3.49Å; R64-L248 PolarHBondContact NH2-O 2.81Å
65E85.5Confident82.4Confident93 Ų9354.3 Ų54.344%0.43529%0.293SS..PPolyproline II helixtrans-64.5140.2-175.1-63.7-175.9170.800111.7E63 T182 W184E63-E65 PolarHBondContact O-N 2.92Å; E65-T182 HydrophobicContact CB-CG2 4.46Å; E65-W184 PolarHBondContact O-NE1 3.09Å
66A84.2Confident81.7Confident38 Ų3852.7 Ų52.731%0.31428%0.284SS..PPolyproline II helixtrans-66.6146.1170.900000110.9R68 T237 K238A66-R68 PolarHBondContact O-N 2.92Å; A66-T237 WeakPolarHBondContact CB-O 3.4Å; A66-K238 HydrophobicContact CB-CB 4.43Å; A66-K238 HydrophobicContact CB-CG 3.58Å
67L82Confident81.2Confident2 Ų253.6 Ų53.61%0.0129%0.29CS..PPolyproline II helixtrans-65.1126.2175.6-72.1165.7000109.8E178 L179 T182 T233 A234 T237 K238L67-E178 HydrophobicContact CD2-CG 4.12Å; L67-L179 HydrophobicContact CD1-CD2 3.45Å; L67-L179 VanDerWaalsContact CD1-CD2 3.45Å; L67-L179 HydrophobicContact CD2-CD2 4.04Å; L67-L179 HydrophobicContact CD2-CG 4.48Å; L67-L179 HydrophobicContact CG-CD2 4.25Å; L67-T182 HydrophobicContact CD2-CG2 4.49Å; L67-T233 HydrophobicContact CD1-CG2 3.68Å; L67-A234 HydrophobicContact CB-CB 4.18Å; L67-T237 HydrophobicContact CB-CG2 4.33Å; L67-T237 HydrophobicContact CD1-CG2 3.74Å; L67-T237 HydrophobicContact CG-CG2 3.95Å; L67-T237 PolarHBondContact N-OG1 3.28Å; L67-K238 VanDerWaalsContact O-CE 3.26Å; L67-K238 WeakPolarHBondContact O-CE 3.16Å
68R71.4Confident81Confident197 Ų19752.3 Ų52.374%0.74328%0.282SS*.PPolyproline II helixtrans-72.9136.3169-62.3-174.6-174.7-167.11.9108.1A66 D70 L73A66-R68 PolarHBondContact O-N 2.92Å; R68-D70 VanDerWaalsContact C-N 3.27Å; R68-D70 PolarHBondContact O-N 3.17Å; R68-L73 WeakPolarHBondContact O-CD1 3.26Å
69V64.1Low80.8Confident100 Ų10052.6 Ų52.661%0.60628%0.279SS*.  trans-72.991.9171.6179.40000106.2A234V69-A234 HydrophobicContact CG2-CB 3.93Å
70D67.6Low80.7Confident50 Ų5049.9 Ų49.927%0.26726%0.258SS..  trans-104.7115175.8-175.1-18.1000107.7R68 G72 L73 K173R68-D70 VanDerWaalsContact C-N 3.27Å; R68-D70 PolarHBondContact O-N 3.17Å; D70-G72 PolarHBondContact O-N 3.44Å; D70-G72 WeakPolarHBondContact OD1-CA 3.43Å; D70-G72 PolarHBondContact OD1-N 3.41Å; D70-L73 HydrophobicContact CB-CB 4.5Å; D70-L73 HydrophobicContact CB-CD1 3.73Å; D70-L73 HydrophobicContact CB-CG 3.89Å; D70-L73 WeakPolarHBondContact O-CB 3.21Å; D70-L73 PolarHBondContact O-N 3.11Å; D70-K173 WeakPolarHBondContact OD2-CD 3.29Å; D70-K173 WeakPolarHBondContact OD2-CE 3.4Å; D70-K173 IonicContact OD2-NZ 3.07Å; D70-K173 PolarHBondContact OD2-NZ 3.45Å
71P65.1Low80.3Confident134 Ų13447.9 Ų47.987%0.8725%0.25SC*.THydrogen-bonded Turntrans-57.6-17.8176.2-2333000113.9
72G65.6Low80Confident17 Ų1755.8 Ų55.818%0.17528%0.284CS..THydrogen-bonded Turntrans-83.3-13.8174.200000114.6D70 S74 A172 K173D70-G72 PolarHBondContact O-N 3.44Å; D70-G72 WeakPolarHBondContact OD1-CA 3.43Å; D70-G72 PolarHBondContact OD1-N 3.41Å; G72-S74 PolarHBondContact O-N 2.8Å; G72-A172 CarbonylContact O-C 3.55Å; G72-A172 VanDerWaalsContact O-CA 3.29Å; G72-A172 WeakPolarHBondContact O-CA 3.3Å; G72-K173 PolarHBondContact O-N 2.85Å
73L71.4Confident80.1Confident26 Ų2653 Ų5314%0.13628%0.275CS..EExtended strand (participates in β ladder)trans-67.4119.2175.6-80.9161.8000109.8R68 D70 K173 A175 E178 M230R68-L73 WeakPolarHBondContact O-CD1 3.26Å; D70-L73 HydrophobicContact CB-CB 4.5Å; D70-L73 HydrophobicContact CB-CD1 3.73Å; D70-L73 HydrophobicContact CB-CG 3.89Å; D70-L73 WeakPolarHBondContact O-CB 3.21Å; D70-L73 PolarHBondContact O-N 3.11Å; L73-K173 HydrophobicContact CD2-CB 4.4Å; L73-A175 HydrophobicContact CB-CB 4.46Å; L73-A175 HydrophobicContact CD2-CB 4.24Å; L73-E178 HydrophobicContact CD2-CB 3.56Å; L73-E178 HydrophobicContact CD2-CG 3.96Å; L73-M230 HydrophobicContact CB-CE 4.34Å; L73-M230 HydrophobicContact CD1-CE 4.46Å
74S76.2Confident80.4Confident30 Ų3050.8 Ų50.821%0.2127%0.269CS..EExtended strand (participates in β ladder)trans-131.1131.2178.2-1740000110.8G72 M76 K173 A175G72-S74 PolarHBondContact O-N 2.8Å; S74-M76 PolarHBondContact OG-N 2.63Å; S74-M76 PolarHBondContact OG-O 3.16Å; S74-K173 PolarHBondContact N-O 3.35Å; S74-A175 PolarHBondContact O-N 2.82Å
75L77.1Confident80.6Confident23 Ų2351 Ų5112%0.1228%0.275CS..SBendtrans-73.2-19.6165.5-71.3167000111.7P77 A175 L179 A226 F229 M230 L252 L256L75-P77 WeakPolarHBondContact O-CD 3.31Å; L75-A175 HydrophobicContact CD2-CB 3.72Å; L75-A175 HydrophobicContact CG-CB 3.84Å; L75-L179 HydrophobicContact CD2-CD1 4.49Å; L75-A226 HydrophobicContact CB-CB 4.39Å; L75-A226 HydrophobicContact CD1-CB 4.03Å; L75-F229 HydrophobicContact CD1-CD1 3.58Å; L75-F229 HydrophobicContact CD1-CE1 3.86Å; L75-M230 HydrophobicContact CD1-CG 3.82Å; L75-M230 HydrophobicContact CD1-SD 3.93Å; L75-M230 HydrophobicContact CD2-SD 4.25Å; L75-M230 HydrophobicContact CG-CG 4.05Å; L75-M230 HydrophobicContact CG-SD 3.94Å; L75-L252 HydrophobicContact CD2-CD1 3.54Å; L75-L252 HydrophobicContact CD2-CD2 3.78Å; L75-L252 HydrophobicContact CD2-CG 4.33Å; L75-L256 HydrophobicContact CD1-CD1 3.94Å; L75-L256 HydrophobicContact CD1-CD2 3.84Å
76M79.9Confident81.1Confident12 Ų1251.5 Ų51.56%0.05929%0.286CS..  trans-122.873.5-179.4-60.3-177.7-69.500108.9S74 W78 F79 L145 I146 A226S74-M76 PolarHBondContact OG-N 2.63Å; S74-M76 PolarHBondContact OG-O 3.16Å; M76-W78 HydrophobicContact CB-CD2 4.42Å; M76-W78 HydrophobicContact CB-CH2 3.91Å; M76-W78 HydrophobicContact CB-CZ2 3.88Å; M76-W78 HydrophobicContact CB-CZ3 4.27Å; M76-W78 HydrophobicContact CG-CH2 3.73Å; M76-W78 HydrophobicContact CG-CZ2 3.7Å; M76-W78 PolarHBondContact O-N 3.31Å; M76-W78 VanDerWaalsContact O-N 3.11Å; M76-W78 HydrophobicContact SD-CH2 3.58Å; M76-W78 VanDerWaalsContact SD-CH2 3.58Å; M76-W78 HydrophobicContact SD-CZ2 4.15Å; M76-W78 HydrophobicContact SD-CZ3 4.27Å; M76-F79 HydrophobicContact CB-CB 3.66Å; M76-F79 HydrophobicContact CE-CD1 4.37Å; M76-F79 HydrophobicContact CE-CG 4.45Å; M76-F79 WeakPolarHBondContact O-CB 3.34Å; M76-F79 PolarHBondContact O-N 2.88Å; M76-L145 HydrophobicContact SD-CB 4.39Å; M76-L145 HydrophobicContact SD-CD1 4.41Å; M76-I146 HydrophobicContact CG-CD1 4.2Å; M76-I146 HydrophobicContact CG-CG1 3.9Å; M76-I146 HydrophobicContact SD-CG1 4.32Å; M76-A226 HydrophobicContact CE-CB 3.9Å
77P82.6Confident81.7Confident21 Ų2152.8 Ų52.814%0.13629%0.291CS..THydrogen-bonded Turntrans-62.3-22.1-177.326-34.8000112.3L75 F79 K168 K169L75-P77 WeakPolarHBondContact O-CD 3.31Å; P77-F79 VanDerWaalsContact C-N 3.34Å; P77-K168 HydrophobicContact CB-CG 4.28Å; P77-K168 CarbonylContact O-C 3.54Å; P77-K168 VanDerWaalsContact O-CA 3.3Å; P77-K168 WeakPolarHBondContact O-CA 3.39Å; P77-K169 PolarHBondContact O-N 3Å
78W89.2Confident82.3Confident18 Ų1852.7 Ų52.77%0.06829%0.29CS..THydrogen-bonded Turntrans-82.8-2.9174.446.2-103000114.1M76 H80 F100 L101 V102 L145 I146 I149 P166M76-W78 HydrophobicContact CB-CD2 4.42Å; M76-W78 HydrophobicContact CB-CH2 3.91Å; M76-W78 HydrophobicContact CB-CZ2 3.88Å; M76-W78 HydrophobicContact CB-CZ3 4.27Å; M76-W78 HydrophobicContact CG-CH2 3.73Å; M76-W78 HydrophobicContact CG-CZ2 3.7Å; M76-W78 PolarHBondContact O-N 3.31Å; M76-W78 VanDerWaalsContact O-N 3.11Å; M76-W78 HydrophobicContact SD-CH2 3.58Å; M76-W78 VanDerWaalsContact SD-CH2 3.58Å; M76-W78 HydrophobicContact SD-CZ2 4.15Å; M76-W78 HydrophobicContact SD-CZ3 4.27Å; W78-H80 PolarHBondContact O-CD2 2.98Å; W78-H80 VanDerWaalsContact O-CD2 3.31Å; W78-F100 HydrophobicContact CB-CD2 4.41Å; W78-F100 HydrophobicContact CB-CE2 3.79Å; W78-F100 HydrophobicContact CB-CZ 4.41Å; W78-F100 HydrophobicContact CD2-CE2 4.25Å; W78-F100 AromaticContact CG-CE2 3.77Å; W78-F100 HydrophobicContact CG-CE2 3.77Å; W78-F100 HydrophobicContact CG-CZ 4.32Å; W78-L101 WeakPolarHBondContact O-CA 3.44Å; W78-V102 HydrophobicContact CD2-CG2 4.5Å; W78-V102 HydrophobicContact CE3-CB 3.58Å; W78-V102 HydrophobicContact CE3-CG2 3.38Å; W78-V102 HydrophobicContact CZ3-CB 3.59Å; W78-V102 HydrophobicContact CZ3-CG1 4.2Å; W78-V102 HydrophobicContact CZ3-CG2 3.45Å; W78-V102 VanDerWaalsContact CZ3-CG2 3.45Å; W78-V102 PolarHBondContact O-N 2.83Å; W78-L145 HydrophobicContact CH2-CB 3.44Å; W78-L145 VanDerWaalsContact CH2-CB 3.44Å; W78-L145 HydrophobicContact CH2-CD1 4.34Å; W78-L145 HydrophobicContact CH2-CG 4.47Å; W78-L145 HydrophobicContact CZ2-CB 4.47Å; W78-L145 HydrophobicContact CZ3-CB 4.03Å; W78-L145 HydrophobicContact CZ3-CD1 4.26Å; W78-I146 HydrophobicContact CZ2-CG1 4.23Å; W78-I149 HydrophobicContact CD2-CG1 4.2Å; W78-I149 HydrophobicContact CE3-CG1 4.26Å; W78-I149 HydrophobicContact CH2-CG1 3.88Å; W78-I149 HydrophobicContact CZ2-CB 4.22Å; W78-I149 HydrophobicContact CZ2-CG1 3.73Å; W78-I149 HydrophobicContact CZ3-CG1 4.12Å; W78-P166 HydrophobicContact CB-CB 3.84Å; W78-P166 HydrophobicContact CG-CB 4.34Å
79F88Confident83.6Confident40 Ų4045.9 Ų45.918%0.17527%0.27CS..BIsolated β-bridgetrans-92.3116.2177.4-176.9-109000111.1M76 P77 V102 E104 Y112 L145M76-F79 HydrophobicContact CB-CB 3.66Å; M76-F79 HydrophobicContact CE-CD1 4.37Å; M76-F79 HydrophobicContact CE-CG 4.45Å; M76-F79 WeakPolarHBondContact O-CB 3.34Å; M76-F79 PolarHBondContact O-N 2.88Å; P77-F79 VanDerWaalsContact C-N 3.34Å; F79-V102 WeakPolarHBondContact CA-O 3.33Å; F79-V102 HydrophobicContact CD2-CB 4.15Å; F79-V102 HydrophobicContact CD2-CG1 3.94Å; F79-V102 HydrophobicContact CE2-CG1 4.32Å; F79-E104 HydrophobicContact CE2-CG 4.35Å; F79-E104 HydrophobicContact CZ-CG 3.89Å; F79-Y112 AromaticContact CE2-CD1 3.77Å; F79-Y112 HydrophobicContact CE2-CD1 3.77Å; F79-Y112 AromaticContact CE2-CE1 3.84Å; F79-Y112 HydrophobicContact CE2-CE1 3.84Å; F79-Y112 HydrophobicContact CZ-CD1 4.36Å; F79-Y112 HydrophobicContact CZ-CE1 4.04Å; F79-L145 HydrophobicContact CD2-CD1 4.35Å; F79-L145 HydrophobicContact CE2-CD1 4.45Å
80H89.1Confident85.1Confident11 Ų1143.6 Ų43.65%0.05127%0.267CS..  trans-97.4-5.7-175.4-71.4-120.2000113.2W78 I83 K91 V102 R167W78-H80 PolarHBondContact O-CD2 2.98Å; W78-H80 VanDerWaalsContact O-CD2 3.31Å; H80-I83 HydrophobicContact CB-CD1 3.59Å; H80-I83 HydrophobicContact CB-CG1 3.99Å; H80-I83 HydrophobicContact CB-CG2 4.23Å; H80-K91 WeakPolarHBondContact ND1-CD 3.42Å; H80-V102 PolarHBondContact N-O 3.03Å; H80-R167 PolarHBondContact NE2-O 3.37Å
81G85.4Confident86.4Confident8 Ų844.3 Ų44.38%0.08227%0.267CS..  trans69.2-139.4-176.500000112.2I83 R103 E104G81-I83 PolarHBondContact O-N 3.09Å; G81-R103 WeakPolarHBondContact O-CA 3.22Å; G81-R103 WeakPolarHBondContact O-CB 3.44Å; G81-E104 PolarHBondContact O-N 2.81Å
82K86.8Confident87.9Confident169 Ų16937.9 Ų37.974%0.73523%0.226SC*.SBendtrans-77.582.7-178.5-63.4-179.2-178.2178.70111.9E104K82-E104 WeakPolarHBondContact CE-OE2 3.4Å; K82-E104 HydrophobicContact CG-CB 4.19Å; K82-E104 HydrophobicContact CG-CG 4.37Å; K82-E104 WeakPolarHBondContact CG-OE2 3.45Å
83I92.5Very high89.3Confident24 Ų2440.8 Ų40.812%0.12324%0.235CC..  trans-117.8152.1168.363.4165.6000110.9H80 G81 T87 A88 K91 L101 R103H80-I83 HydrophobicContact CB-CD1 3.59Å; H80-I83 HydrophobicContact CB-CG1 3.99Å; H80-I83 HydrophobicContact CB-CG2 4.23Å; G81-I83 PolarHBondContact O-N 3.09Å; I83-T87 HydrophobicContact CB-CG2 4.18Å; I83-T87 HydrophobicContact CG2-CG2 4.45Å; I83-A88 HydrophobicContact CD1-CB 3.88Å; I83-K91 HydrophobicContact CD1-CD 4.19Å; I83-L101 HydrophobicContact CD1-CD1 4.04Å; I83-L101 HydrophobicContact CD1-CD2 4.42Å; I83-R103 HydrophobicContact CD1-CB 4.31Å; I83-R103 HydrophobicContact CG1-CB 3.63Å; I83-R103 HydrophobicContact CG1-CG 4.4Å; I83-R103 WeakPolarHBondContact O-CD 3.49Å
84S94.9Very high90.4Very high41 Ų4144.4 Ų44.429%0.28726%0.26SS..  trans-72.7159.4176.381.30000111.8P86 T87 A88S84-P86 WeakPolarHBondContact OG-CD 3.15Å; S84-T87 PolarHBondContact O-N 3.34Å; S84-T87 WeakPolarHBondContact OG-CB 3.46Å; S84-T87 PolarHBondContact OG-N 3.32Å; S84-T87 VanDerWaalsContact OG-N 3.07Å; S84-T87 PolarHBondContact OG-OG1 2.81Å; S84-A88 PolarHBondContact O-N 2.88Å
85G94.1Very high91.3Very high16 Ų1646 Ų4617%0.16527%0.269CS..Hα-helixtrans-53.3-52.2171.100000112.6T87 A88 V89G85-T87 VanDerWaalsContact C-N 3.32Å; G85-T87 PolarHBondContact O-N 3.32Å; G85-A88 WeakPolarHBondContact O-CA 3.32Å; G85-A88 WeakPolarHBondContact O-CB 3.09Å; G85-A88 PolarHBondContact O-N 2.76Å; G85-V89 WeakPolarHBondContact O-CG2 3.3Å; G85-V89 PolarHBondContact O-N 2.77Å
86P96.4Very high92.2Very high104 Ų10449.4 Ų49.468%0.67529%0.285SS*.Hα-helixtrans-56.9-41.2175.5-28.535.9000113.9S84 A88 V89 G90S84-P86 WeakPolarHBondContact OG-CD 3.15Å; P86-A88 VanDerWaalsContact C-N 3.3Å; P86-A88 PolarHBondContact O-N 2.78Å; P86-V89 PolarHBondContact O-N 2.71Å; P86-G90 PolarHBondContact O-N 2.61Å
87T95.9Very high93.1Very high66 Ų6652.7 Ų52.741%0.40530%0.303SS..Hα-helixtrans-61.9-39174.9-53.20000111.7I83 S84 G85 K91I83-T87 HydrophobicContact CB-CG2 4.18Å; I83-T87 HydrophobicContact CG2-CG2 4.45Å; S84-T87 PolarHBondContact O-N 3.34Å; S84-T87 WeakPolarHBondContact OG-CB 3.46Å; S84-T87 PolarHBondContact OG-N 3.32Å; S84-T87 VanDerWaalsContact OG-N 3.07Å; S84-T87 PolarHBondContact OG-OG1 2.81Å; G85-T87 VanDerWaalsContact C-N 3.32Å; G85-T87 PolarHBondContact O-N 3.32Å; T87-K91 HydrophobicContact CG2-CD 4.42Å; T87-K91 WeakPolarHBondContact O-CG 3.42Å; T87-K91 PolarHBondContact O-N 3.07Å
88A95.9Very high93.7Very high0 Ų051.7 Ų51.70%030%0.296CS..Hα-helixtrans-64.6-44.5175.600000111.9I83 S84 G85 P86 G90 K91 L92 L101 C115I83-A88 HydrophobicContact CD1-CB 3.88Å; S84-A88 PolarHBondContact O-N 2.88Å; G85-A88 WeakPolarHBondContact O-CA 3.32Å; G85-A88 WeakPolarHBondContact O-CB 3.09Å; G85-A88 PolarHBondContact O-N 2.76Å; P86-A88 VanDerWaalsContact C-N 3.3Å; P86-A88 PolarHBondContact O-N 2.78Å; A88-G90 VanDerWaalsContact C-N 3.34Å; A88-G90 PolarHBondContact O-N 3.46Å; A88-K91 PolarHBondContact O-N 3.28Å; A88-K91 VanDerWaalsContact O-N 3.1Å; A88-L92 WeakPolarHBondContact O-CG 3.32Å; A88-L92 PolarHBondContact O-N 2.76Å; A88-L101 HydrophobicContact CB-CD1 3.92Å; A88-L101 HydrophobicContact CB-CD2 4.27Å; A88-C115 HydrophobicContact CB-CB 4.49Å
89V97Very high94.2Very high53 Ų5351.2 Ų51.232%0.32130%0.295SS..Hα-helixtrans-57.8-47.4176.1176.10000110.9G85 P86 K91 L92 V122G85-V89 WeakPolarHBondContact O-CG2 3.3Å; G85-V89 PolarHBondContact O-N 2.77Å; P86-V89 PolarHBondContact O-N 2.71Å; V89-K91 VanDerWaalsContact C-N 3.27Å; V89-K91 PolarHBondContact O-N 3.25Å; V89-L92 PolarHBondContact O-N 3.16Å; V89-L92 VanDerWaalsContact O-N 3.17Å; V89-V122 HydrophobicContact CG1-CG2 4.17Å; V89-V122 HydrophobicContact CG2-CB 4.03Å; V89-V122 HydrophobicContact CG2-CG1 4.05Å; V89-V122 HydrophobicContact CG2-CG2 4.38Å
90G96.2Very high94.6Very high52 Ų5249.5 Ų49.554%0.53629%0.287SS..Hα-helixtrans-63.3-31.4176.700000113.4P86 A88P86-G90 PolarHBondContact O-N 2.61Å; A88-G90 VanDerWaalsContact C-N 3.34Å; A88-G90 PolarHBondContact O-N 3.46Å
91K96Very high95Very high65 Ų6549 Ų4928%0.28329%0.285SS..Hα-helixtrans-75.3-24.6175.8-76.2-178.2-177.6-61.50113.4H80 I83 T87 A88 V89 Q93 L101 R167H80-K91 WeakPolarHBondContact ND1-CD 3.42Å; I83-K91 HydrophobicContact CD1-CD 4.19Å; T87-K91 HydrophobicContact CG2-CD 4.42Å; T87-K91 WeakPolarHBondContact O-CG 3.42Å; T87-K91 PolarHBondContact O-N 3.07Å; A88-K91 PolarHBondContact O-N 3.28Å; A88-K91 VanDerWaalsContact O-N 3.1Å; V89-K91 VanDerWaalsContact C-N 3.27Å; V89-K91 PolarHBondContact O-N 3.25Å; K91-Q93 PolarHBondContact O-N 2.7Å; K91-L101 HydrophobicContact CB-CD2 3.95Å; K91-R167 WeakPolarHBondContact O-CD 3.39Å; K91-R167 WeakPolarHBondContact O-CG 3.21Å; K91-R167 PolarHBondContact O-NE 2.96Å
92L96.6Very high95.5Very high0 Ų048.6 Ų48.60%028%0.281CS..THydrogen-bonded Turntrans-86.132.1176.9-66.9171.5000112.4A88 V89 L99 L101 C115 V122 R167A88-L92 WeakPolarHBondContact O-CG 3.32Å; A88-L92 PolarHBondContact O-N 2.76Å; V89-L92 PolarHBondContact O-N 3.16Å; V89-L92 VanDerWaalsContact O-N 3.17Å; L92-L99 HydrophobicContact CB-CD2 4.3Å; L92-L99 HydrophobicContact CD2-CD2 4.05Å; L92-L99 HydrophobicContact CD2-CG 3.75Å; L92-L101 HydrophobicContact CD1-CD2 4.48Å; L92-L101 HydrophobicContact CD1-CG 4.38Å; L92-L101 HydrophobicContact CD2-CD2 4.05Å; L92-L101 HydrophobicContact CD2-CG 4.17Å; L92-L101 HydrophobicContact CG-CD2 3.96Å; L92-L101 HydrophobicContact CG-CG 4.29Å; L92-C115 HydrophobicContact CD1-CB 3.77Å; L92-V122 HydrophobicContact CB-CG2 4.16Å; L92-V122 HydrophobicContact CD1-CG1 3.58Å; L92-V122 HydrophobicContact CD1-CG2 4.08Å; L92-R167 HydrophobicContact CD2-CB 3.97Å; L92-R167 HydrophobicContact CD2-CG 4.43Å
93Q94.4Very high95.8Very high78 Ų7841.8 Ų41.836%0.36425%0.251SS..  trans-110.5145.9174.6-61.5-60.6-44.200110.7K91 R167K91-Q93 PolarHBondContact O-N 2.7Å; Q93-R167 PolarHBondContact O-NH2 2.93Å
94P95.1Very high95.7Very high102 Ų10243.6 Ų43.666%0.66226%0.259SS*.SBendcis-66.1156.9-7.230.2-35.8000112.3Q96P94-Q96 PolarHBondContact O-N 2.91Å
95P93.9Very high95.4Very high62 Ų6242.2 Ų42.240%0.40325%0.249SC..  trans-65132.3-177.1-16.831.2000110.5
96Q97.2Very high95.1Very high96 Ų9647 Ų4745%0.44927%0.269SS..  trans-147.2127.8178.6176.5-176.613.200107.9P94 G98 L99 S117P94-Q96 PolarHBondContact O-N 2.91Å; Q96-G98 PolarHBondContact O-N 3.47Å; Q96-L99 HydrophobicContact CB-CB 4.02Å; Q96-L99 WeakPolarHBondContact O-CB 3.26Å; Q96-L99 PolarHBondContact O-N 3.29Å; Q96-S117 WeakPolarHBondContact O-CB 3.45Å
97D97.8Very high94.6Very high81 Ų8152.7 Ų52.743%0.43328%0.277SS..THydrogen-bonded Turntrans-60.2127.4-179.3-72.3-6000110.8L99 S117 F118 S119D97-L99 VanDerWaalsContact C-N 3.29Å; D97-L99 PolarHBondContact O-N 2.7Å; D97-S117 WeakPolarHBondContact CA-O 3.28Å; D97-F118 HydrophobicContact CB-CD2 4.06Å; D97-F118 WeakPolarHBondContact OD1-CA 3.47Å; D97-S119 PolarHBondContact OD1-N 3.26Å
98G96.3Very high94.2Very high0 Ų053.1 Ų53.10%028%0.275CS..THydrogen-bonded Turntrans78.46.4-176.900000114.4Q96 S117 V164 T165Q96-G98 PolarHBondContact O-N 3.47Å; G98-S117 PolarHBondContact N-O 2.87Å; G98-V164 PolarHBondContact O-N 3.29Å; G98-T165 PolarHBondContact O-N 2.77Å; G98-T165 VanDerWaalsContact O-N 3.08Å
99L98Very high93.6Very high7 Ų759 Ų594%0.03731%0.313CS..EExtended strand (participates in β ladder)trans-69.9127.3167.4-179.771.5000109.3L92 Q96 D97 S117 T165 R167L92-L99 HydrophobicContact CB-CD2 4.3Å; L92-L99 HydrophobicContact CD2-CD2 4.05Å; L92-L99 HydrophobicContact CD2-CG 3.75Å; Q96-L99 HydrophobicContact CB-CB 4.02Å; Q96-L99 WeakPolarHBondContact O-CB 3.26Å; Q96-L99 PolarHBondContact O-N 3.29Å; D97-L99 VanDerWaalsContact C-N 3.29Å; D97-L99 PolarHBondContact O-N 2.7Å; L99-S117 PolarHBondContact O-N 2.92Å; L99-T165 VanDerWaalsContact CA-O 3.31Å; L99-T165 WeakPolarHBondContact CA-O 3.45Å; L99-T165 HydrophobicContact CD1-CG2 3.84Å; L99-T165 WeakPolarHBondContact CD1-O 3.38Å; L99-R167 HydrophobicContact CD1-CB 4.07Å; L99-R167 HydrophobicContact CG-CB 4.49Å
100F98.1Very high92.8Very high4 Ų459 Ų592%0.01832%0.323CS..EExtended strand (participates in β ladder)trans-141.3161.4-172.674.5-85.3000114.6W78 L114 C115 V116 I149 L163 T165 P166 R167W78-F100 HydrophobicContact CB-CD2 4.41Å; W78-F100 HydrophobicContact CB-CE2 3.79Å; W78-F100 HydrophobicContact CB-CZ 4.41Å; W78-F100 HydrophobicContact CD2-CE2 4.25Å; W78-F100 AromaticContact CG-CE2 3.77Å; W78-F100 HydrophobicContact CG-CE2 3.77Å; W78-F100 HydrophobicContact CG-CZ 4.32Å; F100-L114 HydrophobicContact CB-CD1 4.27Å; F100-L114 HydrophobicContact CD2-CD1 3.96Å; F100-L114 HydrophobicContact CG-CD1 4.49Å; F100-C115 CarbonylContact C-O 3.51Å; F100-C115 WeakPolarHBondContact CA-O 3.23Å; F100-C115 WeakPolarHBondContact CB-O 3.34Å; F100-V116 HydrophobicContact CB-CG2 4.28Å; F100-I149 HydrophobicContact CD2-CD1 4.12Å; F100-I149 HydrophobicContact CE2-CD1 3.75Å; F100-I149 HydrophobicContact CE2-CG1 4.34Å; F100-I149 HydrophobicContact CE2-CG2 3.76Å; F100-I149 HydrophobicContact CZ-CG2 3.63Å; F100-L163 HydrophobicContact CB-CD2 3.86Å; F100-L163 HydrophobicContact CD1-CB 3.78Å; F100-L163 HydrophobicContact CD1-CD2 4.06Å; F100-L163 HydrophobicContact CD1-CG 4.34Å; F100-L163 HydrophobicContact CD2-CD1 4.28Å; F100-L163 HydrophobicContact CD2-CD2 4.42Å; F100-L163 HydrophobicContact CE1-CB 3.77Å; F100-L163 HydrophobicContact CE2-CD1 4.28Å; F100-L163 HydrophobicContact CG-CB 4.37Å; F100-L163 HydrophobicContact CG-CD1 4.41Å; F100-L163 HydrophobicContact CG-CD2 3.86Å; F100-L163 HydrophobicContact CG-CG 4.44Å; F100-L163 HydrophobicContact CZ-CB 4.35Å; F100-L163 HydrophobicContact CZ-CD1 4.39Å; F100-T165 VanDerWaalsContact CD1-O 3.23Å; F100-T165 WeakPolarHBondContact CD1-O 3.19Å; F100-T165 PolarHBondContact N-O 2.85Å; F100-P166 HydrophobicContact CE1-CB 3.93Å; F100-P166 HydrophobicContact CE2-CB 4.33Å; F100-P166 HydrophobicContact CZ-CB 3.7Å; F100-R167 VanDerWaalsContact O-CB 3.28Å; F100-R167 WeakPolarHBondContact O-CB 3.44Å; F100-R167 PolarHBondContact O-N 3.28Å
101L96.9Very high92.6Very high0 Ų057.2 Ų57.20%030%0.301CS..EExtended strand (participates in β ladder)trans-147.8162.3164.664.782.7000110.7W78 I83 A88 K91 L92 R103 C115 R167W78-L101 WeakPolarHBondContact O-CA 3.44Å; I83-L101 HydrophobicContact CD1-CD1 4.04Å; I83-L101 HydrophobicContact CD1-CD2 4.42Å; A88-L101 HydrophobicContact CB-CD1 3.92Å; A88-L101 HydrophobicContact CB-CD2 4.27Å; K91-L101 HydrophobicContact CB-CD2 3.95Å; L92-L101 HydrophobicContact CD1-CD2 4.48Å; L92-L101 HydrophobicContact CD1-CG 4.38Å; L92-L101 HydrophobicContact CD2-CD2 4.05Å; L92-L101 HydrophobicContact CD2-CG 4.17Å; L92-L101 HydrophobicContact CG-CD2 3.96Å; L92-L101 HydrophobicContact CG-CG 4.29Å; L101-R103 HydrophobicContact CD1-CB 4.34Å; L101-C115 HydrophobicContact CD1-CB 4.05Å; L101-C115 HydrophobicContact CG-CB 4.21Å; L101-C115 PolarHBondContact N-O 2.92Å; L101-C115 PolarHBondContact O-N 3.12Å; L101-R167 HydrophobicContact CB-CB 4.27Å; L101-R167 HydrophobicContact CD2-CG 4.5Å
102V94.7Very high92.5Very high0 Ų055.3 Ų55.30%029%0.293CS..EExtended strand (participates in β ladder)trans-115.4142.4171.2-177.50000109.7W78 F79 H80 V113 L114 L145 I149W78-V102 HydrophobicContact CD2-CG2 4.5Å; W78-V102 HydrophobicContact CE3-CB 3.58Å; W78-V102 HydrophobicContact CE3-CG2 3.38Å; W78-V102 HydrophobicContact CZ3-CB 3.59Å; W78-V102 HydrophobicContact CZ3-CG1 4.2Å; W78-V102 HydrophobicContact CZ3-CG2 3.45Å; W78-V102 VanDerWaalsContact CZ3-CG2 3.45Å; W78-V102 PolarHBondContact O-N 2.83Å; F79-V102 WeakPolarHBondContact CA-O 3.33Å; F79-V102 HydrophobicContact CD2-CB 4.15Å; F79-V102 HydrophobicContact CD2-CG1 3.94Å; F79-V102 HydrophobicContact CE2-CG1 4.32Å; H80-V102 PolarHBondContact N-O 3.03Å; V102-V113 WeakPolarHBondContact CA-O 3.37Å; V102-L114 HydrophobicContact CG2-CD1 3.84Å; V102-L145 HydrophobicContact CG1-CD1 4.14Å; V102-L145 HydrophobicContact CG1-CD2 4.13Å; V102-I149 HydrophobicContact CG2-CD1 3.89Å
103R93Very high92.5Very high27 Ų2755.8 Ų55.810%0.10230%0.296CS..EExtended strand (participates in β ladder)trans-136.8163.1176.262.2177-178.179-2.5110.8G81 I83 L101 Y112 V113G81-R103 WeakPolarHBondContact O-CA 3.22Å; G81-R103 WeakPolarHBondContact O-CB 3.44Å; I83-R103 HydrophobicContact CD1-CB 4.31Å; I83-R103 HydrophobicContact CG1-CB 3.63Å; I83-R103 HydrophobicContact CG1-CG 4.4Å; I83-R103 WeakPolarHBondContact O-CD 3.49Å; L101-R103 HydrophobicContact CD1-CB 4.34Å; R103-Y112 CarbonylContact O-C 3.55Å; R103-Y112 WeakPolarHBondContact O-CA 3.42Å; R103-V113 HydrophobicContact CG-CB 3.92Å; R103-V113 PolarHBondContact N-O 2.89Å; R103-V113 PolarHBondContact O-N 3.41Å
104E90.5Very high92.6Very high62 Ų6252 Ų5229%0.2928%0.278SS..EExtended strand (participates in β ladder)trans-69.4146.8169.5-70.2176.2-13700111F79 G81 K82 I106 Y112F79-E104 HydrophobicContact CE2-CG 4.35Å; F79-E104 HydrophobicContact CZ-CG 3.89Å; G81-E104 PolarHBondContact O-N 2.81Å; K82-E104 WeakPolarHBondContact CE-OE2 3.4Å; K82-E104 HydrophobicContact CG-CB 4.19Å; K82-E104 HydrophobicContact CG-CG 4.37Å; K82-E104 WeakPolarHBondContact CG-OE2 3.45Å; E104-I106 PolarHBondContact O-N 3.49Å; E104-Y112 HydrophobicContact CG-CD1 4.32Å; E104-Y112 HydrophobicContact CG-CE1 4.29Å
105S89.2Confident92.8Very high12 Ų1247.2 Ų47.28%0.08425%0.247CC..  trans-78.3117171.8-179.80000109.9H108 D111S105-H108 VanDerWaalsContact CB-O 3.32Å; S105-H108 WeakPolarHBondContact CB-O 3.46Å; S105-H108 PolarHBondContact OG-N 2.79Å; S105-H108 PolarHBondContact OG-O 3.3Å; S105-D111 WeakPolarHBondContact CB-O 3.34Å; S105-D111 PolarHBondContact N-O 3.42Å
106I87.2Confident93Very high115 Ų11544.2 Ų44.259%0.5923%0.227SC*.SBendtrans-74.5-31.9174.1-58.6172.1000110.7E104E104-I106 PolarHBondContact O-N 3.49Å
107R86.7Confident93Very high225 Ų22539.7 Ų39.785%0.84921%0.206SC*.SBendtrans-79.8-29.2-177-63.2-175.1-162.3171.44.8113
108H88.1Confident93Very high75 Ų7538.5 Ų38.535%0.34720%0.197SC..SBendtrans-130.889.7-177-52.7105.3000108.3S105 G110 D111 R126S105-H108 VanDerWaalsContact CB-O 3.32Å; S105-H108 WeakPolarHBondContact CB-O 3.46Å; S105-H108 PolarHBondContact OG-N 2.79Å; S105-H108 PolarHBondContact OG-O 3.3Å; H108-G110 PolarHBondContact O-N 3.19Å; H108-D111 HydrophobicContact CB-CB 4.12Å; H108-D111 WeakPolarHBondContact CB-OD2 3.4Å; H108-D111 WeakPolarHBondContact O-CB 3.18Å; H108-D111 PolarHBondContact O-N 3.4Å; H108-D111 VanDerWaalsContact O-N 3.09Å; H108-R126 PolarHBondContact CD2-NH2 3.19Å; H108-R126 VanDerWaalsContact CD2-NH2 3.32Å; H108-R126 PolarHBondContact CE1-NH1 3.18Å; H108-R126 VanDerWaalsContact CG-CZ 3.42Å; H108-R126 PolarHBondContact ND1-NE 2.81Å; H108-R126 PolarHBondContact NE2-NH1 2.93Å
109P83.7Confident93Very high123 Ų12342 Ų4280%0.79922%0.221SC*.THydrogen-bonded Turntrans-54.1130.1179.6-26.535.2000111.6
110G80.2Confident92.8Very high53 Ų5350.1 Ų50.155%0.54626%0.257SS..THydrogen-bonded Turntrans100-24.6-176.100000114.3H108H108-G110 PolarHBondContact O-N 3.19Å
111D90.8Very high92.7Very high14 Ų1455.9 Ų55.98%0.07528%0.284CS..  trans-85.6166.2175.1-73.7-13.4000112.5S105 H108 R126 V127 Y129S105-D111 WeakPolarHBondContact CB-O 3.34Å; S105-D111 PolarHBondContact N-O 3.42Å; H108-D111 HydrophobicContact CB-CB 4.12Å; H108-D111 WeakPolarHBondContact CB-OD2 3.4Å; H108-D111 WeakPolarHBondContact O-CB 3.18Å; H108-D111 PolarHBondContact O-N 3.4Å; H108-D111 VanDerWaalsContact O-N 3.09Å; D111-R126 IonicContact OD2-CZ 2.72Å; D111-R126 IonicContact OD2-NE 3.61Å; D111-R126 PolarHBondContact OD2-NE 2.97Å; D111-R126 IonicContact OD2-NH2 2.72Å; D111-R126 PolarHBondContact OD2-NH2 3.19Å; D111-V127 WeakPolarHBondContact CB-O 3.47Å; D111-Y129 PolarHBondContact OD1-N 2.8Å
112Y93.6Very high92.8Very high25 Ų2557.2 Ų57.210%0.09829%0.292CS..EExtended strand (participates in β ladder)trans-116.4170.5172.7-52.7-82.5000111.7F79 R103 E104 V127 L134 L145F79-Y112 AromaticContact CE2-CD1 3.77Å; F79-Y112 HydrophobicContact CE2-CD1 3.77Å; F79-Y112 AromaticContact CE2-CE1 3.84Å; F79-Y112 HydrophobicContact CE2-CE1 3.84Å; F79-Y112 HydrophobicContact CZ-CD1 4.36Å; F79-Y112 HydrophobicContact CZ-CE1 4.04Å; R103-Y112 CarbonylContact O-C 3.55Å; R103-Y112 WeakPolarHBondContact O-CA 3.42Å; E104-Y112 HydrophobicContact CG-CD1 4.32Å; E104-Y112 HydrophobicContact CG-CE1 4.29Å; Y112-V127 PolarHBondContact N-O 2.81Å; Y112-V127 PolarHBondContact O-N 2.8Å; Y112-L134 HydrophobicContact CD2-CD2 3.85Å; Y112-L134 HydrophobicContact CE2-CD2 4Å; Y112-L145 HydrophobicContact CD1-CD1 4.04Å; Y112-L145 HydrophobicContact CD2-CD1 4.15Å; Y112-L145 HydrophobicContact CD2-CD2 4.12Å; Y112-L145 HydrophobicContact CD2-CG 4.35Å; Y112-L145 HydrophobicContact CE1-CD1 4.07Å; Y112-L145 HydrophobicContact CE2-CD1 4.2Å; Y112-L145 HydrophobicContact CG-CD1 4.05Å; Y112-L145 HydrophobicContact CG-CD2 4.22Å
113V96.6Very high92.9Very high10 Ų1060.2 Ų60.26%0.06131%0.305CS..EExtended strand (participates in β ladder)trans-133.3120.8171.7-1740000109.1V102 R103 H124 Y125V102-V113 WeakPolarHBondContact CA-O 3.37Å; R103-V113 HydrophobicContact CG-CB 3.92Å; R103-V113 PolarHBondContact N-O 2.89Å; R103-V113 PolarHBondContact O-N 3.41Å; V113-H124 HydrophobicContact CG1-CB 3.99Å; V113-Y125 CarbonylContact C-O 3.58Å; V113-Y125 VanDerWaalsContact CA-O 3.25Å; V113-Y125 WeakPolarHBondContact CA-O 3.21Å; V113-Y125 WeakPolarHBondContact CG1-O 3.4Å
114L97.8Very high93.2Very high0 Ų062.8 Ų62.80%032%0.318CS..EExtended strand (participates in β ladder)trans-85.9122.1168.4171.363.8000108.4F100 V102 V116 Y125 V127 I136 I149 L159 L163F100-L114 HydrophobicContact CB-CD1 4.27Å; F100-L114 HydrophobicContact CD2-CD1 3.96Å; F100-L114 HydrophobicContact CG-CD1 4.49Å; V102-L114 HydrophobicContact CG2-CD1 3.84Å; L114-V116 HydrophobicContact CD1-CG2 4.12Å; L114-V116 HydrophobicContact CD2-CG2 4.17Å; L114-V116 HydrophobicContact CG-CG2 3.79Å; L114-Y125 PolarHBondContact N-O 2.86Å; L114-Y125 PolarHBondContact O-N 3.24Å; L114-V127 HydrophobicContact CB-CG2 3.99Å; L114-I136 HydrophobicContact CD2-CD1 3.94Å; L114-I149 HydrophobicContact CD1-CD1 3.86Å; L114-L159 HydrophobicContact CD2-CD1 3.86Å; L114-L159 HydrophobicContact CD2-CD2 4.07Å; L114-L163 HydrophobicContact CD1-CD1 4.38Å; L114-L163 HydrophobicContact CD1-CD2 4.29Å; L114-L163 HydrophobicContact CD2-CD1 4.35Å; L114-L163 HydrophobicContact CD2-CD2 4.32Å
115C98.2Very high93.5Very high0 Ų061.6 Ų61.60%031%0.311CS..EExtended strand (participates in β ladder)trans-109.1122.3178.8-55.50000108.6A88 L92 F100 L101 V122 F123 H124A88-C115 HydrophobicContact CB-CB 4.49Å; L92-C115 HydrophobicContact CD1-CB 3.77Å; F100-C115 CarbonylContact C-O 3.51Å; F100-C115 WeakPolarHBondContact CA-O 3.23Å; F100-C115 WeakPolarHBondContact CB-O 3.34Å; L101-C115 HydrophobicContact CD1-CB 4.05Å; L101-C115 HydrophobicContact CG-CB 4.21Å; L101-C115 PolarHBondContact N-O 2.92Å; L101-C115 PolarHBondContact O-N 3.12Å; C115-V122 HydrophobicContact CB-CG1 4.27Å; C115-F123 CarbonylContact C-O 3.52Å; C115-F123 VanDerWaalsContact CA-O 3.29Å; C115-F123 WeakPolarHBondContact CA-O 3.44Å; C115-H124 PolarHBondContact SG-ND1 2.85Å
116V98.3Very high93.9Very high0 Ų066.2 Ų66.20%033%0.326CS..EExtended strand (participates in β ladder)trans-126.4127-174.9-171.40000109.5F100 L114 V122 F123 Y125 T161 L163F100-V116 HydrophobicContact CB-CG2 4.28Å; L114-V116 HydrophobicContact CD1-CG2 4.12Å; L114-V116 HydrophobicContact CD2-CG2 4.17Å; L114-V116 HydrophobicContact CG-CG2 3.79Å; V116-V122 CarbonylContact O-C 3.41Å; V116-V122 WeakPolarHBondContact O-CA 3.41Å; V116-F123 PolarHBondContact N-O 2.85Å; V116-F123 PolarHBondContact O-N 2.97Å; V116-Y125 HydrophobicContact CB-CE2 4.36Å; V116-Y125 HydrophobicContact CG2-CD2 4.14Å; V116-Y125 HydrophobicContact CG2-CE2 4.06Å; V116-T161 HydrophobicContact CG1-CG2 4Å; V116-L163 HydrophobicContact CG1-CD2 4.22Å; V116-L163 HydrophobicContact CG2-CD2 3.7Å
117S98.2Very high94.3Very high0 Ų060.7 Ų60.70%030%0.298CS..EExtended strand (participates in β ladder)trans-83.1128.6171.4-1720000109.9Q96 D97 G98 L99 E121Q96-S117 WeakPolarHBondContact O-CB 3.45Å; D97-S117 WeakPolarHBondContact CA-O 3.28Å; G98-S117 PolarHBondContact N-O 2.87Å; L99-S117 PolarHBondContact O-N 2.92Å; S117-E121 CarbonylContact C-O 3.51Å; S117-E121 VanDerWaalsContact CA-O 3.26Å; S117-E121 WeakPolarHBondContact CA-O 3.47Å; S117-E121 PolarHBondContact OG-O 3.28Å
118F97.9Very high94.6Very high56 Ų5651.8 Ų51.825%0.24627%0.267CS..EExtended strand (participates in β ladder)trans-154.3136.4176.5-179.3-111.2000109.8D97 K120 E121 F123 V160 T161D97-F118 HydrophobicContact CB-CD2 4.06Å; D97-F118 WeakPolarHBondContact OD1-CA 3.47Å; F118-K120 PolarHBondContact O-N 3.09Å; F118-E121 PolarHBondContact N-O 3.49Å; F118-E121 PolarHBondContact O-N 3.22Å; F118-F123 HydrophobicContact CB-CD2 4.14Å; F118-F123 HydrophobicContact CB-CE2 4.08Å; F118-F123 HydrophobicContact CD1-CE2 4.25Å; F118-V160 HydrophobicContact CB-CB 4.42Å; F118-V160 HydrophobicContact CB-CG2 3.73Å; F118-V160 HydrophobicContact CD1-CB 3.86Å; F118-V160 HydrophobicContact CD1-CG2 4.12Å; F118-V160 HydrophobicContact CE1-CB 4.44Å; F118-V160 HydrophobicContact CG-CB 4.24Å; F118-V160 HydrophobicContact CG-CG2 4.05Å; F118-T161 HydrophobicContact CB-CG2 4.11Å; F118-T161 HydrophobicContact CD2-CG2 3.7Å; F118-T161 HydrophobicContact CE2-CG2 4.48Å; F118-T161 HydrophobicContact CG-CG2 4.13Å
119S96.4Very high94.5Very high73 Ų7351.6 Ų51.651%0.5126%0.264SS..THydrogen-bonded Turntrans52.140178.7-64.10000113.2D97 E121D97-S119 PolarHBondContact OD1-N 3.26Å; S119-E121 PolarHBondContact O-N 3.21Å
120K93.6Very high94.4Very high178 Ų17851.3 Ų51.377%0.77425%0.252SS*.THydrogen-bonded Turntrans67.20.9-176.8-53.6174.1-179.4175.20115.9F118F118-K120 PolarHBondContact O-N 3.09Å
121E96.1Very high94.4Very high126 Ų12655.2 Ų55.259%0.58926%0.26SS*.EExtended strand (participates in β ladder)trans-103.7167.8174-62.7-169.9155.400111.1S117 F118 S119 F123S117-E121 CarbonylContact C-O 3.51Å; S117-E121 VanDerWaalsContact CA-O 3.26Å; S117-E121 WeakPolarHBondContact CA-O 3.47Å; S117-E121 PolarHBondContact OG-O 3.28Å; F118-E121 PolarHBondContact N-O 3.49Å; F118-E121 PolarHBondContact O-N 3.22Å; S119-E121 PolarHBondContact O-N 3.21Å; E121-F123 HydrophobicContact CB-CE2 3.99Å; E121-F123 HydrophobicContact CB-CZ 4.45Å
122V97.9Very high93.3Very high27 Ų2759.9 Ų59.916%0.16429%0.285CS..EExtended strand (participates in β ladder)trans-120.3115.3175175.60000109.2V89 L92 C115 V116V89-V122 HydrophobicContact CG1-CG2 4.17Å; V89-V122 HydrophobicContact CG2-CB 4.03Å; V89-V122 HydrophobicContact CG2-CG1 4.05Å; V89-V122 HydrophobicContact CG2-CG2 4.38Å; L92-V122 HydrophobicContact CB-CG2 4.16Å; L92-V122 HydrophobicContact CD1-CG1 3.58Å; L92-V122 HydrophobicContact CD1-CG2 4.08Å; C115-V122 HydrophobicContact CB-CG1 4.27Å; V116-V122 CarbonylContact O-C 3.41Å; V116-V122 WeakPolarHBondContact O-CA 3.41Å
123F98.1Very high92.8Very high63 Ų6362.5 Ų62.528%0.27630%0.297SS..EExtended strand (participates in β ladder)trans-90.5137.4177.6-66.3-94000110.2C115 V116 F118 E121 Y125 V160C115-F123 CarbonylContact C-O 3.52Å; C115-F123 VanDerWaalsContact CA-O 3.29Å; C115-F123 WeakPolarHBondContact CA-O 3.44Å; V116-F123 PolarHBondContact N-O 2.85Å; V116-F123 PolarHBondContact O-N 2.97Å; F118-F123 HydrophobicContact CB-CD2 4.14Å; F118-F123 HydrophobicContact CB-CE2 4.08Å; F118-F123 HydrophobicContact CD1-CE2 4.25Å; E121-F123 HydrophobicContact CB-CE2 3.99Å; E121-F123 HydrophobicContact CB-CZ 4.45Å; F123-Y125 HydrophobicContact CB-CD2 4.47Å; F123-Y125 HydrophobicContact CB-CE2 3.68Å; F123-V160 HydrophobicContact CB-CG2 4.31Å; F123-V160 HydrophobicContact CD1-CG1 3.86Å; F123-V160 HydrophobicContact CD2-CG1 4.21Å; F123-V160 HydrophobicContact CD2-CG2 3.81Å; F123-V160 HydrophobicContact CE1-CG1 3.9Å; F123-V160 HydrophobicContact CE2-CG1 4.24Å; F123-V160 HydrophobicContact CE2-CG2 4.34Å; F123-V160 HydrophobicContact CG-CG1 4.03Å; F123-V160 HydrophobicContact CG-CG2 4.01Å; F123-V160 HydrophobicContact CZ-CG1 4.1Å
124H97.9Very high92.4Very high82 Ų8262 Ų6238%0.3829%0.294SS..EExtended strand (participates in β ladder)trans-115.5107.6-179.3-66.8-85.3000110.3V113 C115V113-H124 HydrophobicContact CG1-CB 3.99Å; C115-H124 PolarHBondContact SG-ND1 2.85Å
125Y97.8Very high92.2Very high36 Ų3662.2 Ų62.214%0.14130%0.295CS..EExtended strand (participates in β ladder)trans-95.8121.4176.4-61.4-86.3000109.7V113 L114 V116 F123 V127 I136 L159 V160V113-Y125 CarbonylContact C-O 3.58Å; V113-Y125 VanDerWaalsContact CA-O 3.25Å; V113-Y125 WeakPolarHBondContact CA-O 3.21Å; V113-Y125 WeakPolarHBondContact CG1-O 3.4Å; L114-Y125 PolarHBondContact N-O 2.86Å; L114-Y125 PolarHBondContact O-N 3.24Å; V116-Y125 HydrophobicContact CB-CE2 4.36Å; V116-Y125 HydrophobicContact CG2-CD2 4.14Å; V116-Y125 HydrophobicContact CG2-CE2 4.06Å; F123-Y125 HydrophobicContact CB-CD2 4.47Å; F123-Y125 HydrophobicContact CB-CE2 3.68Å; Y125-V127 PolarHBondContact O-N 2.96Å; Y125-I136 HydrophobicContact CD1-CG2 3.96Å; Y125-I136 HydrophobicContact CG-CG2 4.37Å; Y125-L159 HydrophobicContact CD1-CD2 3.75Å; Y125-L159 HydrophobicContact CD2-CD2 3.78Å; Y125-L159 HydrophobicContact CE1-CD2 3.81Å; Y125-L159 HydrophobicContact CE2-CD2 3.84Å; Y125-L159 HydrophobicContact CG-CD2 3.73Å; Y125-V160 HydrophobicContact CE2-CG2 4.48Å; Y125-V160 WeakPolarHBondContact OH-CG1 3.23Å; Y125-V160 WeakPolarHBondContact OH-CG2 3.44Å; Y125-V160 PolarHBondContact OH-N 2.84Å
126R96.4Very high92.2Very high109 Ų10963.5 Ų63.541%0.41130%0.302SS..EExtended strand (participates in β ladder)trans-68.9127.3168.8-176.5-177.9-178.5-177.5-4.2108H108 D111 I128H108-R126 PolarHBondContact CD2-NH2 3.19Å; H108-R126 VanDerWaalsContact CD2-NH2 3.32Å; H108-R126 PolarHBondContact CE1-NH1 3.18Å; H108-R126 VanDerWaalsContact CG-CZ 3.42Å; H108-R126 PolarHBondContact ND1-NE 2.81Å; H108-R126 PolarHBondContact NE2-NH1 2.93Å; D111-R126 IonicContact OD2-CZ 2.72Å; D111-R126 IonicContact OD2-NE 3.61Å; D111-R126 PolarHBondContact OD2-NE 2.97Å; D111-R126 IonicContact OD2-NH2 2.72Å; D111-R126 PolarHBondContact OD2-NH2 3.19Å; R126-I128 HydrophobicContact CG-CG1 4.14Å
127V95.8Very high91.9Very high0 Ų065.6 Ų65.60%031%0.313CS..EExtended strand (participates in β ladder)trans-104.7107.6172.2-176.30000106.1D111 Y112 L114 Y125 L134 T135 I136 L145 M148D111-V127 WeakPolarHBondContact CB-O 3.47Å; Y112-V127 PolarHBondContact N-O 2.81Å; Y112-V127 PolarHBondContact O-N 2.8Å; L114-V127 HydrophobicContact CB-CG2 3.99Å; Y125-V127 PolarHBondContact O-N 2.96Å; V127-L134 HydrophobicContact CG1-CB 4.07Å; V127-L134 HydrophobicContact CG1-CD2 3.84Å; V127-L134 HydrophobicContact CG1-CG 4.45Å; V127-T135 CarbonylContact C-O 3.59Å; V127-T135 WeakPolarHBondContact CA-O 3.3Å; V127-I136 HydrophobicContact CG2-CD1 4.17Å; V127-I136 HydrophobicContact CG2-CG1 3.97Å; V127-L145 HydrophobicContact CG1-CD2 4.24Å; V127-M148 HydrophobicContact CB-SD 4.46Å; V127-M148 HydrophobicContact CG1-CE 4.26Å; V127-M148 HydrophobicContact CG1-SD 3.59Å; V127-M148 VanDerWaalsContact CG1-SD 3.59Å; V127-M148 HydrophobicContact CG2-CE 3.94Å; V127-M148 HydrophobicContact CG2-SD 3.99Å
128I93.9Very high91.6Very high37 Ų3770 Ų7019%0.1934%0.336CS..EExtended strand (participates in β ladder)trans-81.4129.4-176.6-58.1170.9000108.2R126 Q130 L134 T135R126-I128 HydrophobicContact CG-CG1 4.14Å; I128-Q130 HydrophobicContact CG2-CB 4.36Å; I128-L134 CarbonylContact O-C 3.53Å; I128-L134 VanDerWaalsContact O-CA 3.28Å; I128-L134 WeakPolarHBondContact O-CA 3.15Å; I128-T135 HydrophobicContact CB-CG2 4.22Å; I128-T135 PolarHBondContact N-O 3.36Å; I128-T135 PolarHBondContact O-N 3.46Å
129Y84.8Confident91.3Very high72 Ų7275.3 Ų75.328%0.28236%0.362SS..EExtended strand (participates in β ladder)trans-103.9112.1170.7-178.3-108.3000110.3D111 N132 K133 L134 C222D111-Y129 PolarHBondContact OD1-N 2.8Å; Y129-N132 WeakPolarHBondContact OH-CA 3.31Å; Y129-N132 PolarHBondContact OH-OD1 3.45Å; Y129-K133 WeakPolarHBondContact CA-O 3.28Å; Y129-K133 WeakPolarHBondContact CD2-O 3.36Å; Y129-L134 HydrophobicContact CD2-CD2 3.64Å; Y129-L134 HydrophobicContact CD2-CG 4.05Å; Y129-L134 HydrophobicContact CG-CD2 4.2Å; Y129-C222 WeakPolarHBondContact CE2-SG 3.37Å; Y129-C222 PolarHBondContact OH-SG 3.44Å
130Q83.1Confident91.1Very high116 Ų11675.4 Ų75.454%0.54236%0.355SS..EExtended strand (participates in β ladder)trans-146.9142.3-179.6-174.1176.8-9.200110.4I128 N132 K133I128-Q130 HydrophobicContact CG2-CB 4.36Å; Q130-N132 PolarHBondContact O-N 2.97Å; Q130-K133 PolarHBondContact N-O 2.78Å; Q130-K133 PolarHBondContact O-N 2.76Å
131D78.7Confident90.9Very high135 Ų13571.9 Ų71.972%0.72234%0.337SS*.THydrogen-bonded Turntrans52.339.7177.3-56.8-36.8000113.8K133D131-K133 PolarHBondContact O-N 2.87Å
132N69.3Low90.4Very high113 Ų11366.5 Ų66.560%0.60431%0.312SS*.THydrogen-bonded Turntrans58.427.9-175.6-57-45000114.5Y129 Q130Y129-N132 WeakPolarHBondContact OH-CA 3.31Å; Y129-N132 PolarHBondContact OH-OD1 3.45Å; Q130-N132 PolarHBondContact O-N 2.97Å
133K82Confident89.3Confident80 Ų8072.5 Ų72.535%0.34833%0.333SS..EExtended strand (participates in β ladder)trans-133.3157.7175.4-63.6-176-177.2-179.60110.9Y129 Q130 D131 Y141 F142Y129-K133 WeakPolarHBondContact CA-O 3.28Å; Y129-K133 WeakPolarHBondContact CD2-O 3.36Å; Q130-K133 PolarHBondContact N-O 2.78Å; Q130-K133 PolarHBondContact O-N 2.76Å; D131-K133 PolarHBondContact O-N 2.87Å; K133-Y141 HydrophobicContact CB-CD1 4.06Å; K133-Y141 HydrophobicContact CD-CD1 4.3Å; K133-Y141 HydrophobicContact CD-CG 4.39Å; K133-F142 CarbonylContact C-O 3.59Å; K133-F142 VanDerWaalsContact CA-O 3.25Å; K133-F142 WeakPolarHBondContact CA-O 3.41Å
134L88.4Confident88.3Confident0 Ų070.2 Ų70.20%032%0.323CS..EExtended strand (participates in β ladder)trans-111.1142.1176.2-65.1162.1000110.2Y112 V127 I128 Y129 Y141 F142 L145 D223Y112-L134 HydrophobicContact CD2-CD2 3.85Å; Y112-L134 HydrophobicContact CE2-CD2 4Å; V127-L134 HydrophobicContact CG1-CB 4.07Å; V127-L134 HydrophobicContact CG1-CD2 3.84Å; V127-L134 HydrophobicContact CG1-CG 4.45Å; I128-L134 CarbonylContact O-C 3.53Å; I128-L134 VanDerWaalsContact O-CA 3.28Å; I128-L134 WeakPolarHBondContact O-CA 3.15Å; Y129-L134 HydrophobicContact CD2-CD2 3.64Å; Y129-L134 HydrophobicContact CD2-CG 4.05Å; Y129-L134 HydrophobicContact CG-CD2 4.2Å; L134-Y141 CarbonylContact O-C 3.59Å; L134-Y141 VanDerWaalsContact O-CA 3.3Å; L134-Y141 WeakPolarHBondContact O-CA 3.38Å; L134-F142 HydrophobicContact CB-CB 4.37Å; L134-F142 PolarHBondContact N-O 3.31Å; L134-F142 PolarHBondContact O-N 3.45Å; L134-L145 HydrophobicContact CD1-CB 4.48Å; L134-L145 HydrophobicContact CD1-CD2 4.07Å; L134-L145 HydrophobicContact CD1-CG 3.94Å; L134-D223 WeakPolarHBondContact CD1-OD2 3.26Å
135T94.6Very high87.6Confident4 Ų466.3 Ų66.33%0.02531%0.305CS..EExtended strand (participates in β ladder)trans-150.1156172.1-173.10000111.7V127 I128 D137 N138 Q140 Y141V127-T135 CarbonylContact C-O 3.59Å; V127-T135 WeakPolarHBondContact CA-O 3.3Å; I128-T135 HydrophobicContact CB-CG2 4.22Å; I128-T135 PolarHBondContact N-O 3.36Å; I128-T135 PolarHBondContact O-N 3.46Å; T135-D137 PolarHBondContact OG1-N 2.72Å; T135-N138 VanDerWaalsContact CG2-OD1 3.31Å; T135-N138 WeakPolarHBondContact CG2-OD1 3.15Å; T135-N138 WeakPolarHBondContact OG1-CA 3.4Å; T135-N138 PolarHBondContact OG1-N 2.8Å; T135-Q140 WeakPolarHBondContact CB-O 3.31Å; T135-Q140 PolarHBondContact OG1-O 2.89Å; T135-Y141 HydrophobicContact CG2-CD1 4.23Å; T135-Y141 HydrophobicContact CG2-CE1 3.86Å
136I96.4Very high86.9Confident26 Ų2666.8 Ų66.813%0.13331%0.31CS..SBendtrans-106.2-32.6172.1-64.3-179000110.8L114 Y125 V127 M148 Y152 L159L114-I136 HydrophobicContact CD2-CD1 3.94Å; Y125-I136 HydrophobicContact CD1-CG2 3.96Å; Y125-I136 HydrophobicContact CG-CG2 4.37Å; V127-I136 HydrophobicContact CG2-CD1 4.17Å; V127-I136 HydrophobicContact CG2-CG1 3.97Å; I136-M148 HydrophobicContact CD1-SD 4.07Å; I136-M148 HydrophobicContact CG1-SD 4.23Å; I136-Y152 HydrophobicContact CD1-CD2 4.29Å; I136-Y152 HydrophobicContact CD1-CE2 3.59Å; I136-Y152 HydrophobicContact CG1-CE2 4.36Å; I136-L159 HydrophobicContact CD1-CD2 3.93Å
137D92.9Very high86.3Confident44 Ų4462.9 Ų62.924%0.23530%0.297CS..SBendtrans-125.72.1-168.553.823.7000114.4T135 Q139 Q140 S158T135-D137 PolarHBondContact OG1-N 2.72Å; D137-Q139 PolarHBondContact O-N 3.09Å; D137-Q139 PolarHBondContact OD1-N 3.39Å; D137-Q140 PolarHBondContact OD1-N 3.48Å; D137-S158 VanDerWaalsContact OD2-CB 3.26Å; D137-S158 WeakPolarHBondContact OD2-CB 3.28Å; D137-S158 PolarHBondContact OD2-OG 3.19Å
138N92Very high86Confident92 Ų9262.9 Ų62.949%0.49230%0.297SS..SBendtrans5917.4-173.3-56.5-48.1000114.4T135 Y141T135-N138 VanDerWaalsContact CG2-OD1 3.31Å; T135-N138 WeakPolarHBondContact CG2-OD1 3.15Å; T135-N138 WeakPolarHBondContact OG1-CA 3.4Å; T135-N138 PolarHBondContact OG1-N 2.8Å; N138-Y141 PolarHBondContact O-OH 3.38Å
139Q91.2Very high85.9Confident169 Ų16961.5 Ų61.579%0.7929%0.29SS*.SBendtrans-112.1-46.3174.6-62.8-1787.700109.9D137D137-Q139 PolarHBondContact O-N 3.09Å; D137-Q139 PolarHBondContact OD1-N 3.39Å
140Q92.4Very high86Confident75 Ų7561.2 Ų61.235%0.3529%0.291SS..SBendtrans-102130.8176.7-174.36257.800110.7T135 D137 F142 F151T135-Q140 WeakPolarHBondContact CB-O 3.31Å; T135-Q140 PolarHBondContact OG1-O 2.89Å; D137-Q140 PolarHBondContact OD1-N 3.48Å; Q140-F142 HydrophobicContact CB-CE2 4.29Å; Q140-F142 HydrophobicContact CB-CZ 4.25Å; Q140-F142 HydrophobicContact CG-CD2 4.49Å; Q140-F142 HydrophobicContact CG-CE1 3.74Å; Q140-F142 HydrophobicContact CG-CE2 3.61Å; Q140-F142 HydrophobicContact CG-CZ 3.19Å; Q140-F151 HydrophobicContact CG-CE1 4.22Å; Q140-F151 HydrophobicContact CG-CZ 4.19Å
141Y90.4Very high86.5Confident104 Ų10459 Ų5941%0.40828%0.28SS..  trans-119.5146.3179.8-65.7-93.5000111.3K133 L134 T135 N138K133-Y141 HydrophobicContact CB-CD1 4.06Å; K133-Y141 HydrophobicContact CD-CD1 4.3Å; K133-Y141 HydrophobicContact CD-CG 4.39Å; L134-Y141 CarbonylContact O-C 3.59Å; L134-Y141 VanDerWaalsContact O-CA 3.3Å; L134-Y141 WeakPolarHBondContact O-CA 3.38Å; T135-Y141 HydrophobicContact CG2-CD1 4.23Å; T135-Y141 HydrophobicContact CG2-CE1 3.86Å; N138-Y141 PolarHBondContact O-OH 3.38Å
142F85.6Confident87.3Confident12 Ų1252.5 Ų52.55%0.05325%0.245CC..BIsolated β-bridgetrans-132.9153.1-179.8-51.6-81.1000110.5K133 L134 Q140 M148 F151 Y152K133-F142 CarbonylContact C-O 3.59Å; K133-F142 VanDerWaalsContact CA-O 3.25Å; K133-F142 WeakPolarHBondContact CA-O 3.41Å; L134-F142 HydrophobicContact CB-CB 4.37Å; L134-F142 PolarHBondContact N-O 3.31Å; L134-F142 PolarHBondContact O-N 3.45Å; Q140-F142 HydrophobicContact CB-CE2 4.29Å; Q140-F142 HydrophobicContact CB-CZ 4.25Å; Q140-F142 HydrophobicContact CG-CD2 4.49Å; Q140-F142 HydrophobicContact CG-CE1 3.74Å; Q140-F142 HydrophobicContact CG-CE2 3.61Å; Q140-F142 HydrophobicContact CG-CZ 3.19Å; F142-M148 HydrophobicContact CB-CB 3.98Å; F142-M148 HydrophobicContact CD1-CB 4.14Å; F142-M148 HydrophobicContact CD2-CB 3.68Å; F142-M148 HydrophobicContact CD2-CG 3.57Å; F142-M148 HydrophobicContact CD2-SD 4.43Å; F142-M148 HydrophobicContact CE2-CB 4.13Å; F142-M148 HydrophobicContact CE2-CG 3.65Å; F142-M148 HydrophobicContact CG-CB 3.65Å; F142-M148 HydrophobicContact CG-CG 4.09Å; F142-M148 HydrophobicContact CZ-CG 4.22Å; F142-F151 HydrophobicContact CD1-CB 4.44Å; F142-F151 HydrophobicContact CE1-CB 3.47Å; F142-F151 VanDerWaalsContact CE1-CB 3.47Å; F142-F151 AromaticContact CE1-CD1 3.85Å; F142-F151 HydrophobicContact CE1-CD1 3.85Å; F142-F151 HydrophobicContact CE1-CD2 4.11Å; F142-F151 AromaticContact CE1-CG 3.55Å; F142-F151 HydrophobicContact CE1-CG 3.55Å; F142-F151 HydrophobicContact CZ-CB 3.97Å; F142-F151 AromaticContact CZ-CD1 3.52Å; F142-F151 HydrophobicContact CZ-CD1 3.52Å; F142-F151 HydrophobicContact CZ-CE1 4.1Å; F142-F151 AromaticContact CZ-CG 3.76Å; F142-F151 HydrophobicContact CZ-CG 3.76Å; F142-Y152 AromaticContact CE2-CE2 3.76Å; F142-Y152 HydrophobicContact CE2-CE2 3.76Å; F142-Y152 HydrophobicContact CZ-CD2 4.41Å; F142-Y152 AromaticContact CZ-CE2 3.88Å; F142-Y152 HydrophobicContact CZ-CE2 3.88Å
143Y74.4Confident88.5Confident154 Ų15449.6 Ų49.660%0.60423%0.234SC*.SBendtrans-87-20.2178.3-69.1-77.4000113.4
144N76.5Confident89.1Confident15 Ų1552.7 Ų52.78%0.0825%0.247CC..SBendtrans-158166.5178.160.171.4000110.7I146 D147 M148 D223N144-I146 VanDerWaalsContact C-N 3.3Å; N144-I146 PolarHBondContact O-N 3.48Å; N144-I146 WeakPolarHBondContact OD1-CA 3.23Å; N144-I146 WeakPolarHBondContact OD1-CB 3.4Å; N144-I146 PolarHBondContact OD1-N 3.24Å; N144-I146 VanDerWaalsContact OD1-N 3.08Å; N144-D147 PolarHBondContact ND2-OD2 3.24Å; N144-D147 PolarHBondContact O-N 2.84Å; N144-D147 VanDerWaalsContact OD1-CG 3.3Å; N144-D147 PolarHBondContact OD1-N 3.06Å; N144-D147 PolarHBondContact OD1-OD2 2.63Å; N144-M148 PolarHBondContact O-N 3.49Å; N144-D223 WeakPolarHBondContact CA-OD2 3.45Å
145L84.3Confident89.3Confident0 Ų056.3 Ų56.30%027%0.269CS..Hα-helixtrans-68.4-29.2-178-70165.3000111.3M76 W78 F79 V102 Y112 V127 L134 M148 I149 D223M76-L145 HydrophobicContact SD-CB 4.39Å; M76-L145 HydrophobicContact SD-CD1 4.41Å; W78-L145 HydrophobicContact CH2-CB 3.44Å; W78-L145 VanDerWaalsContact CH2-CB 3.44Å; W78-L145 HydrophobicContact CH2-CD1 4.34Å; W78-L145 HydrophobicContact CH2-CG 4.47Å; W78-L145 HydrophobicContact CZ2-CB 4.47Å; W78-L145 HydrophobicContact CZ3-CB 4.03Å; W78-L145 HydrophobicContact CZ3-CD1 4.26Å; F79-L145 HydrophobicContact CD2-CD1 4.35Å; F79-L145 HydrophobicContact CE2-CD1 4.45Å; V102-L145 HydrophobicContact CG1-CD1 4.14Å; V102-L145 HydrophobicContact CG1-CD2 4.13Å; Y112-L145 HydrophobicContact CD1-CD1 4.04Å; Y112-L145 HydrophobicContact CD2-CD1 4.15Å; Y112-L145 HydrophobicContact CD2-CD2 4.12Å; Y112-L145 HydrophobicContact CD2-CG 4.35Å; Y112-L145 HydrophobicContact CE1-CD1 4.07Å; Y112-L145 HydrophobicContact CE2-CD1 4.2Å; Y112-L145 HydrophobicContact CG-CD1 4.05Å; Y112-L145 HydrophobicContact CG-CD2 4.22Å; V127-L145 HydrophobicContact CG1-CD2 4.24Å; L134-L145 HydrophobicContact CD1-CB 4.48Å; L134-L145 HydrophobicContact CD1-CD2 4.07Å; L134-L145 HydrophobicContact CD1-CG 3.94Å; L145-M148 HydrophobicContact CD2-CE 3.55Å; L145-M148 HydrophobicContact CD2-SD 4.32Å; L145-M148 PolarHBondContact O-N 2.83Å; L145-I149 WeakPolarHBondContact O-CB 3.49Å; L145-I149 WeakPolarHBondContact O-CG1 3.31Å; L145-I149 PolarHBondContact O-N 3.47Å; L145-D223 VanDerWaalsContact CB-OD1 3.27Å; L145-D223 WeakPolarHBondContact CB-OD1 3.36Å; L145-D223 HydrophobicContact CD1-CB 4.14Å; L145-D223 HydrophobicContact CG-CB 4.39Å; L145-D223 VanDerWaalsContact CG-CG 3.47Å; L145-D223 VanDerWaalsContact CG-OD2 3.3Å; L145-D223 WeakPolarHBondContact CG-OD2 3.36Å; L145-D223 PolarHBondContact N-OD1 3.1Å; L145-D223 PolarHBondContact N-OD2 3.12Å
146I82.9Confident89.3Confident46 Ų4662.2 Ų62.224%0.23630%0.295CS..Hα-helixtrans-62-50.4177.3-61.6170.8000109.8M76 W78 N144 M148 I149 E150 L256M76-I146 HydrophobicContact CG-CD1 4.2Å; M76-I146 HydrophobicContact CG-CG1 3.9Å; M76-I146 HydrophobicContact SD-CG1 4.32Å; W78-I146 HydrophobicContact CZ2-CG1 4.23Å; N144-I146 VanDerWaalsContact C-N 3.3Å; N144-I146 PolarHBondContact O-N 3.48Å; N144-I146 WeakPolarHBondContact OD1-CA 3.23Å; N144-I146 WeakPolarHBondContact OD1-CB 3.4Å; N144-I146 PolarHBondContact OD1-N 3.24Å; N144-I146 VanDerWaalsContact OD1-N 3.08Å; I146-M148 VanDerWaalsContact C-N 3.32Å; I146-M148 PolarHBondContact O-N 3.49Å; I146-I149 PolarHBondContact O-N 3.39Å; I146-E150 WeakPolarHBondContact O-CB 3.41Å; I146-E150 PolarHBondContact O-N 3.16Å; I146-L256 HydrophobicContact CD1-CD2 4.11Å
147D82.1Confident89.2Confident26 Ų2662.8 Ų62.814%0.13931%0.307CS..Hα-helixtrans-62.1-40.7178.1-63.6-20.3000111.4N144 E150 F151 K254 G255N144-D147 PolarHBondContact ND2-OD2 3.24Å; N144-D147 PolarHBondContact O-N 2.84Å; N144-D147 VanDerWaalsContact OD1-CG 3.3Å; N144-D147 PolarHBondContact OD1-N 3.06Å; N144-D147 PolarHBondContact OD1-OD2 2.63Å; D147-E150 PolarHBondContact O-N 2.86Å; D147-F151 WeakPolarHBondContact O-CB 3.04Å; D147-F151 PolarHBondContact O-N 3.4Å; D147-K254 VanDerWaalsContact OD1-C 3.28Å; D147-K254 VanDerWaalsContact OD1-CA 3.28Å; D147-K254 WeakPolarHBondContact OD1-CA 3.43Å; D147-G255 PolarHBondContact OD1-N 2.83Å
148M90.3Very high89.2Confident0 Ų063.1 Ų63.10%031%0.313CS..Hα-helixtrans-60.4-48.3175.2-177.4-170.778.200111.5V127 I136 F142 N144 L145 I146 F151 Y152V127-M148 HydrophobicContact CB-SD 4.46Å; V127-M148 HydrophobicContact CG1-CE 4.26Å; V127-M148 HydrophobicContact CG1-SD 3.59Å; V127-M148 VanDerWaalsContact CG1-SD 3.59Å; V127-M148 HydrophobicContact CG2-CE 3.94Å; V127-M148 HydrophobicContact CG2-SD 3.99Å; I136-M148 HydrophobicContact CD1-SD 4.07Å; I136-M148 HydrophobicContact CG1-SD 4.23Å; F142-M148 HydrophobicContact CB-CB 3.98Å; F142-M148 HydrophobicContact CD1-CB 4.14Å; F142-M148 HydrophobicContact CD2-CB 3.68Å; F142-M148 HydrophobicContact CD2-CG 3.57Å; F142-M148 HydrophobicContact CD2-SD 4.43Å; F142-M148 HydrophobicContact CE2-CB 4.13Å; F142-M148 HydrophobicContact CE2-CG 3.65Å; F142-M148 HydrophobicContact CG-CB 3.65Å; F142-M148 HydrophobicContact CG-CG 4.09Å; F142-M148 HydrophobicContact CZ-CG 4.22Å; N144-M148 PolarHBondContact O-N 3.49Å; L145-M148 HydrophobicContact CD2-CE 3.55Å; L145-M148 HydrophobicContact CD2-SD 4.32Å; L145-M148 PolarHBondContact O-N 2.83Å; I146-M148 VanDerWaalsContact C-N 3.32Å; I146-M148 PolarHBondContact O-N 3.49Å; M148-F151 PolarHBondContact O-N 3.45Å; M148-Y152 HydrophobicContact CG-CD2 3.71Å; M148-Y152 HydrophobicContact CG-CE2 3.72Å; M148-Y152 VanDerWaalsContact O-CD2 3.23Å; M148-Y152 WeakPolarHBondContact O-CD2 3.25Å; M148-Y152 PolarHBondContact O-N 2.85Å; M148-Y152 HydrophobicContact SD-CE2 4.49Å
149I91.3Very high89.4Confident9 Ų959.1 Ų59.15%0.04629%0.292CS..Hα-helixtrans-66.3-38.9179-66.7-61.2000111W78 F100 V102 L114 L145 I146 Y152 S153 L163W78-I149 HydrophobicContact CD2-CG1 4.2Å; W78-I149 HydrophobicContact CE3-CG1 4.26Å; W78-I149 HydrophobicContact CH2-CG1 3.88Å; W78-I149 HydrophobicContact CZ2-CB 4.22Å; W78-I149 HydrophobicContact CZ2-CG1 3.73Å; W78-I149 HydrophobicContact CZ3-CG1 4.12Å; F100-I149 HydrophobicContact CD2-CD1 4.12Å; F100-I149 HydrophobicContact CE2-CD1 3.75Å; F100-I149 HydrophobicContact CE2-CG1 4.34Å; F100-I149 HydrophobicContact CE2-CG2 3.76Å; F100-I149 HydrophobicContact CZ-CG2 3.63Å; V102-I149 HydrophobicContact CG2-CD1 3.89Å; L114-I149 HydrophobicContact CD1-CD1 3.86Å; L145-I149 WeakPolarHBondContact O-CB 3.49Å; L145-I149 WeakPolarHBondContact O-CG1 3.31Å; L145-I149 PolarHBondContact O-N 3.47Å; I146-I149 PolarHBondContact O-N 3.39Å; I149-Y152 PolarHBondContact O-N 3.19Å; I149-S153 WeakPolarHBondContact O-CB 3.2Å; I149-S153 PolarHBondContact O-N 3.01Å; I149-S153 PolarHBondContact O-OG 2.81Å; I149-L163 HydrophobicContact CB-CD1 4.42Å; I149-L163 HydrophobicContact CD1-CD1 3.47Å; I149-L163 VanDerWaalsContact CD1-CD1 3.47Å; I149-L163 HydrophobicContact CG1-CD1 4.5Å; I149-L163 HydrophobicContact CG2-CD1 4.12Å
150E87.9Confident89.7Confident65 Ų6553.4 Ų53.430%0.30427%0.268SS..Hα-helixtrans-61.9-44.7176.1-169.9-173.4165.600111.1I146 D147 S153 K154I146-E150 WeakPolarHBondContact O-CB 3.41Å; I146-E150 PolarHBondContact O-N 3.16Å; D147-E150 PolarHBondContact O-N 2.86Å; E150-S153 PolarHBondContact O-N 2.82Å; E150-K154 PolarHBondContact O-N 3.24Å; E150-K154 IonicContact OE1-NZ 3.47Å; E150-K154 PolarHBondContact OE1-NZ 3.01Å
151F92.4Very high90Very high69 Ų6951 Ų5130%0.30326%0.259SS..Hα-helixtrans-60-53.4176.5176.1-90.4000111.6Q140 F142 D147 M148 S153 K154 T155Q140-F151 HydrophobicContact CG-CE1 4.22Å; Q140-F151 HydrophobicContact CG-CZ 4.19Å; F142-F151 HydrophobicContact CD1-CB 4.44Å; F142-F151 HydrophobicContact CE1-CB 3.47Å; F142-F151 VanDerWaalsContact CE1-CB 3.47Å; F142-F151 AromaticContact CE1-CD1 3.85Å; F142-F151 HydrophobicContact CE1-CD1 3.85Å; F142-F151 HydrophobicContact CE1-CD2 4.11Å; F142-F151 AromaticContact CE1-CG 3.55Å; F142-F151 HydrophobicContact CE1-CG 3.55Å; F142-F151 HydrophobicContact CZ-CB 3.97Å; F142-F151 AromaticContact CZ-CD1 3.52Å; F142-F151 HydrophobicContact CZ-CD1 3.52Å; F142-F151 HydrophobicContact CZ-CE1 4.1Å; F142-F151 AromaticContact CZ-CG 3.76Å; F142-F151 HydrophobicContact CZ-CG 3.76Å; D147-F151 WeakPolarHBondContact O-CB 3.04Å; D147-F151 PolarHBondContact O-N 3.4Å; M148-F151 PolarHBondContact O-N 3.45Å; F151-S153 PolarHBondContact O-N 2.82Å; F151-K154 PolarHBondContact O-N 2.75Å; F151-T155 PolarHBondContact O-N 3.28Å
152Y96Very high90.3Very high0 Ų048.3 Ų48.30%025%0.253CS..Hα-helixtrans-71-14.8-177.6-75.3-62000114I136 F142 M148 I149 K154 T155 K156 S158 L159 T162 L163I136-Y152 HydrophobicContact CD1-CD2 4.29Å; I136-Y152 HydrophobicContact CD1-CE2 3.59Å; I136-Y152 HydrophobicContact CG1-CE2 4.36Å; F142-Y152 AromaticContact CE2-CE2 3.76Å; F142-Y152 HydrophobicContact CE2-CE2 3.76Å; F142-Y152 HydrophobicContact CZ-CD2 4.41Å; F142-Y152 AromaticContact CZ-CE2 3.88Å; F142-Y152 HydrophobicContact CZ-CE2 3.88Å; M148-Y152 HydrophobicContact CG-CD2 3.71Å; M148-Y152 HydrophobicContact CG-CE2 3.72Å; M148-Y152 VanDerWaalsContact O-CD2 3.23Å; M148-Y152 WeakPolarHBondContact O-CD2 3.25Å; M148-Y152 PolarHBondContact O-N 2.85Å; M148-Y152 HydrophobicContact SD-CE2 4.49Å; I149-Y152 PolarHBondContact O-N 3.19Å; Y152-K154 VanDerWaalsContact C-N 3.35Å; Y152-T155 CarbonylContact C-O 3.58Å; Y152-T155 VanDerWaalsContact CA-O 3.28Å; Y152-T155 WeakPolarHBondContact CA-O 3.41Å; Y152-K156 WeakPolarHBondContact CD1-O 3.42Å; Y152-S158 PolarHBondContact OH-OG 2.94Å; Y152-L159 HydrophobicContact CD1-CD1 3.46Å; Y152-L159 VanDerWaalsContact CD1-CD1 3.46Å; Y152-L159 HydrophobicContact CD1-CG 3.57Å; Y152-L159 HydrophobicContact CD2-CD1 4.17Å; Y152-L159 HydrophobicContact CE1-CD1 4.11Å; Y152-L159 HydrophobicContact CE1-CD2 4.36Å; Y152-L159 HydrophobicContact CE1-CG 3.73Å; Y152-L159 HydrophobicContact CG-CD1 3.5Å; Y152-L159 VanDerWaalsContact CG-CD1 3.5Å; Y152-L159 HydrophobicContact CG-CG 4.08Å; Y152-T162 WeakPolarHBondContact O-CA 3.39Å; Y152-L163 PolarHBondContact O-N 3.01Å
153S94.4Very high90.9Very high52 Ų5248 Ų4836%0.36425%0.252SS..Hα-helixtrans-75-24.9169.4-57.70000112.8I149 E150 F151 L163I149-S153 WeakPolarHBondContact O-CB 3.2Å; I149-S153 PolarHBondContact O-N 3.01Å; I149-S153 PolarHBondContact O-OG 2.81Å; E150-S153 PolarHBondContact O-N 2.82Å; F151-S153 PolarHBondContact O-N 2.82Å; S153-L163 WeakPolarHBondContact CA-O 3.3Å
154K94.5Very high91.9Very high145 Ų14544.8 Ų44.863%0.6325%0.248SC*.Hα-helixtrans-97-27.3179.3-64.6174.6-170.3168.70112.6E150 F151 Y152E150-K154 PolarHBondContact O-N 3.24Å; E150-K154 IonicContact OE1-NZ 3.47Å; E150-K154 PolarHBondContact OE1-NZ 3.01Å; F151-K154 PolarHBondContact O-N 2.75Å; Y152-K154 VanDerWaalsContact C-N 3.35Å
155T93.8Very high92.8Very high76 Ų7646.2 Ų46.247%0.46626%0.257SS..  trans-145.3134.9-174.9-57.10000110.1F151 Y152 G157F151-T155 PolarHBondContact O-N 3.28Å; Y152-T155 CarbonylContact C-O 3.58Å; Y152-T155 VanDerWaalsContact CA-O 3.28Å; Y152-T155 WeakPolarHBondContact CA-O 3.41Å; T155-G157 VanDerWaalsContact C-N 3.27Å; T155-G157 PolarHBondContact O-N 2.9Å
156K93.9Very high93.2Very high127 Ų12748.3 Ų48.355%0.55227%0.271SS*.  trans-64.4-31.9-177.669.5170.5-172.5174.60113.1Y152 S158 L159 T162Y152-K156 WeakPolarHBondContact CD1-O 3.42Å; K156-S158 PolarHBondContact O-N 3.31Å; K156-L159 VanDerWaalsContact O-CB 3.24Å; K156-L159 WeakPolarHBondContact O-CB 3.25Å; K156-L159 WeakPolarHBondContact O-CG 3.33Å; K156-L159 PolarHBondContact O-N 3.36Å; K156-T162 HydrophobicContact CB-CG2 4.1Å
157G93.3Very high93.8Very high39 Ų3950.9 Ų50.940%0.40228%0.278SS..THydrogen-bonded Turntrans50.3-126.6-173.400000111.6T155 L159T155-G157 VanDerWaalsContact C-N 3.27Å; T155-G157 PolarHBondContact O-N 2.9Å; G157-L159 VanDerWaalsContact C-N 3.32Å
158S93.6Very high94.1Very high51 Ų5155.6 Ų55.636%0.35730%0.297SS..THydrogen-bonded Turntrans-81.50.1175.748.50000115D137 Y152 K156D137-S158 VanDerWaalsContact OD2-CB 3.26Å; D137-S158 WeakPolarHBondContact OD2-CB 3.28Å; D137-S158 PolarHBondContact OD2-OG 3.19Å; Y152-S158 PolarHBondContact OH-OG 2.94Å; K156-S158 PolarHBondContact O-N 3.31Å
159L97.1Very high93.9Very high8 Ų860.6 Ų60.64%0.04232%0.319CS..SBendtrans-83.1158.9178.2-51.3-175.9000112.6L114 Y125 I136 Y152 K156 G157 T161 L163L114-L159 HydrophobicContact CD2-CD1 3.86Å; L114-L159 HydrophobicContact CD2-CD2 4.07Å; Y125-L159 HydrophobicContact CD1-CD2 3.75Å; Y125-L159 HydrophobicContact CD2-CD2 3.78Å; Y125-L159 HydrophobicContact CE1-CD2 3.81Å; Y125-L159 HydrophobicContact CE2-CD2 3.84Å; Y125-L159 HydrophobicContact CG-CD2 3.73Å; I136-L159 HydrophobicContact CD1-CD2 3.93Å; Y152-L159 HydrophobicContact CD1-CD1 3.46Å; Y152-L159 VanDerWaalsContact CD1-CD1 3.46Å; Y152-L159 HydrophobicContact CD1-CG 3.57Å; Y152-L159 HydrophobicContact CD2-CD1 4.17Å; Y152-L159 HydrophobicContact CE1-CD1 4.11Å; Y152-L159 HydrophobicContact CE1-CD2 4.36Å; Y152-L159 HydrophobicContact CE1-CG 3.73Å; Y152-L159 HydrophobicContact CG-CD1 3.5Å; Y152-L159 VanDerWaalsContact CG-CD1 3.5Å; Y152-L159 HydrophobicContact CG-CG 4.08Å; K156-L159 VanDerWaalsContact O-CB 3.24Å; K156-L159 WeakPolarHBondContact O-CB 3.25Å; K156-L159 WeakPolarHBondContact O-CG 3.33Å; K156-L159 PolarHBondContact O-N 3.36Å; G157-L159 VanDerWaalsContact C-N 3.32Å; L159-T161 VanDerWaalsContact C-N 3.28Å; L159-T161 WeakPolarHBondContact CB-O 3.38Å; L159-T161 PolarHBondContact O-N 2.92Å; L159-L163 HydrophobicContact CD1-CD2 3.94Å; L159-L163 HydrophobicContact CD1-CG 4.14Å
160V97.1Very high93.5Very high49 Ų4968.7 Ų68.730%0.29736%0.356SS..SBendtrans-63.1-32.5175.1-77.80000112.9F118 F123 Y125F118-V160 HydrophobicContact CB-CB 4.42Å; F118-V160 HydrophobicContact CB-CG2 3.73Å; F118-V160 HydrophobicContact CD1-CB 3.86Å; F118-V160 HydrophobicContact CD1-CG2 4.12Å; F118-V160 HydrophobicContact CE1-CB 4.44Å; F118-V160 HydrophobicContact CG-CB 4.24Å; F118-V160 HydrophobicContact CG-CG2 4.05Å; F123-V160 HydrophobicContact CB-CG2 4.31Å; F123-V160 HydrophobicContact CD1-CG1 3.86Å; F123-V160 HydrophobicContact CD2-CG1 4.21Å; F123-V160 HydrophobicContact CD2-CG2 3.81Å; F123-V160 HydrophobicContact CE1-CG1 3.9Å; F123-V160 HydrophobicContact CE2-CG1 4.24Å; F123-V160 HydrophobicContact CE2-CG2 4.34Å; F123-V160 HydrophobicContact CG-CG1 4.03Å; F123-V160 HydrophobicContact CG-CG2 4.01Å; F123-V160 HydrophobicContact CZ-CG1 4.1Å; Y125-V160 HydrophobicContact CE2-CG2 4.48Å; Y125-V160 WeakPolarHBondContact OH-CG1 3.23Å; Y125-V160 WeakPolarHBondContact OH-CG2 3.44Å; Y125-V160 PolarHBondContact OH-N 2.84Å
161T97.7Very high93Very high25 Ų2568.6 Ų68.615%0.15337%0.373CS..SBendtrans-153.7164.2177.7-169.50000109.9V116 F118 L159V116-T161 HydrophobicContact CG1-CG2 4Å; F118-T161 HydrophobicContact CB-CG2 4.11Å; F118-T161 HydrophobicContact CD2-CG2 3.7Å; F118-T161 HydrophobicContact CE2-CG2 4.48Å; F118-T161 HydrophobicContact CG-CG2 4.13Å; L159-T161 VanDerWaalsContact C-N 3.28Å; L159-T161 WeakPolarHBondContact CB-O 3.38Å; L159-T161 PolarHBondContact O-N 2.92Å
162T97.5Very high92.3Very high47 Ų4766.5 Ų66.529%0.28837%0.368SS..  trans-64.3148.5170.445.80000110.9Y152 K156 V164Y152-T162 WeakPolarHBondContact O-CA 3.39Å; K156-T162 HydrophobicContact CB-CG2 4.1Å; T162-V164 PolarHBondContact O-N 3.26Å
163L97.8Very high91.5Very high5 Ų572 Ų723%0.02639%0.392CS..  trans-72.4126.2171.9-56-177.5000109.6F100 L114 V116 I149 Y152 S153 L159F100-L163 HydrophobicContact CB-CD2 3.86Å; F100-L163 HydrophobicContact CD1-CB 3.78Å; F100-L163 HydrophobicContact CD1-CD2 4.06Å; F100-L163 HydrophobicContact CD1-CG 4.34Å; F100-L163 HydrophobicContact CD2-CD1 4.28Å; F100-L163 HydrophobicContact CD2-CD2 4.42Å; F100-L163 HydrophobicContact CE1-CB 3.77Å; F100-L163 HydrophobicContact CE2-CD1 4.28Å; F100-L163 HydrophobicContact CG-CB 4.37Å; F100-L163 HydrophobicContact CG-CD1 4.41Å; F100-L163 HydrophobicContact CG-CD2 3.86Å; F100-L163 HydrophobicContact CG-CG 4.44Å; F100-L163 HydrophobicContact CZ-CB 4.35Å; F100-L163 HydrophobicContact CZ-CD1 4.39Å; L114-L163 HydrophobicContact CD1-CD1 4.38Å; L114-L163 HydrophobicContact CD1-CD2 4.29Å; L114-L163 HydrophobicContact CD2-CD1 4.35Å; L114-L163 HydrophobicContact CD2-CD2 4.32Å; V116-L163 HydrophobicContact CG1-CD2 4.22Å; V116-L163 HydrophobicContact CG2-CD2 3.7Å; I149-L163 HydrophobicContact CB-CD1 4.42Å; I149-L163 HydrophobicContact CD1-CD1 3.47Å; I149-L163 VanDerWaalsContact CD1-CD1 3.47Å; I149-L163 HydrophobicContact CG1-CD1 4.5Å; I149-L163 HydrophobicContact CG2-CD1 4.12Å; Y152-L163 PolarHBondContact O-N 3.01Å; S153-L163 WeakPolarHBondContact CA-O 3.3Å; L159-L163 HydrophobicContact CD1-CD2 3.94Å; L159-L163 HydrophobicContact CD1-CG 4.14Å
164V95.7Very high90.9Very high87 Ų8770.8 Ų70.853%0.52738%0.384SS..  trans-117-60-175.1-178.30000110.5G98 T162G98-V164 PolarHBondContact O-N 3.29Å; T162-V164 PolarHBondContact O-N 3.26Å
165T94.4Very high90.4Very high44 Ų4463.9 Ų63.927%0.2735%0.354SS..EExtended strand (participates in β ladder)trans-116.6117-171.9-56.40000110.1G98 L99 F100 R167G98-T165 PolarHBondContact O-N 2.77Å; G98-T165 VanDerWaalsContact O-N 3.08Å; L99-T165 VanDerWaalsContact CA-O 3.31Å; L99-T165 WeakPolarHBondContact CA-O 3.45Å; L99-T165 HydrophobicContact CD1-CG2 3.84Å; L99-T165 WeakPolarHBondContact CD1-O 3.38Å; F100-T165 VanDerWaalsContact CD1-O 3.23Å; F100-T165 WeakPolarHBondContact CD1-O 3.19Å; F100-T165 PolarHBondContact N-O 2.85Å; T165-R167 PolarHBondContact O-N 2.66Å
166P93.6Very high89.9Confident45 Ų4565.4 Ų65.429%0.29236%0.356SS..EExtended strand (participates in β ladder)trans-74.3125.7173.627.2-31.6000110.6W78 F100 K168W78-P166 HydrophobicContact CB-CB 3.84Å; W78-P166 HydrophobicContact CG-CB 4.34Å; F100-P166 HydrophobicContact CE1-CB 3.93Å; F100-P166 HydrophobicContact CE2-CB 4.33Å; F100-P166 HydrophobicContact CZ-CB 3.7Å; P166-K168 PolarHBondContact O-N 2.8Å; P166-K168 VanDerWaalsContact O-N 3.1Å
167R94.5Very high89.4Confident100 Ų10065.5 Ų65.538%0.37736%0.358SS..  trans-76.499.5169.6-173.957.5166.7178.3-3.9109.1H80 K91 L92 Q93 L99 F100 L101 T165H80-R167 PolarHBondContact NE2-O 3.37Å; K91-R167 WeakPolarHBondContact O-CD 3.39Å; K91-R167 WeakPolarHBondContact O-CG 3.21Å; K91-R167 PolarHBondContact O-NE 2.96Å; L92-R167 HydrophobicContact CD2-CB 3.97Å; L92-R167 HydrophobicContact CD2-CG 4.43Å; Q93-R167 PolarHBondContact O-NH2 2.93Å; L99-R167 HydrophobicContact CD1-CB 4.07Å; L99-R167 HydrophobicContact CG-CB 4.49Å; F100-R167 VanDerWaalsContact O-CB 3.28Å; F100-R167 WeakPolarHBondContact O-CB 3.44Å; F100-R167 PolarHBondContact O-N 3.28Å; L101-R167 HydrophobicContact CB-CB 4.27Å; L101-R167 HydrophobicContact CD2-CG 4.5Å; T165-R167 PolarHBondContact O-N 2.66Å
168K89.6Confident89.1Confident125 Ų12566.2 Ų66.254%0.54335%0.351SS..PPolyproline II helixtrans-62.6136.3-179.2-58.7-175.5-1781770111.3P77 P166 Q170P77-K168 HydrophobicContact CB-CG 4.28Å; P77-K168 CarbonylContact O-C 3.54Å; P77-K168 VanDerWaalsContact O-CA 3.3Å; P77-K168 WeakPolarHBondContact O-CA 3.39Å; P166-K168 PolarHBondContact O-N 2.8Å; P166-K168 VanDerWaalsContact O-N 3.1Å; K168-Q170 PolarHBondContact O-N 3.19Å
169K86.1Confident88.8Confident104 Ų10463.8 Ų63.845%0.45233%0.334SS..PPolyproline II helixtrans-61.5132.9168.4-176.9-179.8-177.5177.30108.8P77 G171 A172P77-K169 PolarHBondContact O-N 3Å; K169-G171 PolarHBondContact O-N 3.16Å; K169-A172 HydrophobicContact CB-CB 4Å; K169-A172 WeakPolarHBondContact O-CB 3.27Å; K169-A172 PolarHBondContact O-N 2.86Å
170Q83.3Confident88.3Confident179 Ų17966.8 Ų66.884%0.83636%0.355SS*.THydrogen-bonded Turntrans-60.5131.4-179.2-167.2174.97.200110K168 A172K168-Q170 PolarHBondContact O-N 3.19Å; Q170-A172 VanDerWaalsContact C-N 3.26Å; Q170-A172 PolarHBondContact O-N 2.77Å
171G77.4Confident87.7Confident64 Ų6470.7 Ų70.766%0.6637%0.368SS*.THydrogen-bonded Turntrans80-3.7-174.900000115.1K169K169-G171 PolarHBondContact O-N 3.16Å
172A77Confident87.2Confident24 Ų2469.7 Ų69.720%0.19836%0.362CS..PPolyproline II helixtrans-76.2126.4176.300000111.4G72 K169 Q170G72-A172 CarbonylContact O-C 3.55Å; G72-A172 VanDerWaalsContact O-CA 3.29Å; G72-A172 WeakPolarHBondContact O-CA 3.3Å; K169-A172 HydrophobicContact CB-CB 4Å; K169-A172 WeakPolarHBondContact O-CB 3.27Å; K169-A172 PolarHBondContact O-N 2.86Å; Q170-A172 VanDerWaalsContact C-N 3.26Å; Q170-A172 PolarHBondContact O-N 2.77Å
173K79.3Confident86.7Confident115 Ų11568.1 Ų68.150%0.536%0.355SS..EExtended strand (participates in β ladder)trans-97.9143.7168.9-63177.9-171.4163.30108.8D70 G72 L73 S74 A175D70-K173 WeakPolarHBondContact OD2-CD 3.29Å; D70-K173 WeakPolarHBondContact OD2-CE 3.4Å; D70-K173 IonicContact OD2-NZ 3.07Å; D70-K173 PolarHBondContact OD2-NZ 3.45Å; G72-K173 PolarHBondContact O-N 2.85Å; L73-K173 HydrophobicContact CD2-CB 4.4Å; S74-K173 PolarHBondContact N-O 3.35Å; K173-A175 PolarHBondContact O-N 3.12Å
174S82.7Confident86.4Confident27 Ų2768.2 Ų68.219%0.18936%0.356CS..EExtended strand (participates in β ladder)trans-71118.4177.51730000110.1E176 Q177 E178S174-E176 VanDerWaalsContact C-N 3.3Å; S174-E176 PolarHBondContact OG-N 2.66Å; S174-Q177 PolarHBondContact O-N 2.89Å; S174-Q177 PolarHBondContact OG-N 3.48Å; S174-E178 PolarHBondContact O-N 2.96Å; S174-E178 VanDerWaalsContact O-N 3.16Å
175A82.4Confident86.1Confident0 Ų066.3 Ų66.30%034%0.342CS..Hα-helixtrans-63.3-37.8174.200000111.9L73 S74 L75 K173 Q177 E178 L179 M230L73-A175 HydrophobicContact CB-CB 4.46Å; L73-A175 HydrophobicContact CD2-CB 4.24Å; S74-A175 PolarHBondContact O-N 2.82Å; L75-A175 HydrophobicContact CD2-CB 3.72Å; L75-A175 HydrophobicContact CG-CB 3.84Å; K173-A175 PolarHBondContact O-N 3.12Å; A175-Q177 PolarHBondContact O-N 3.01Å; A175-E178 PolarHBondContact O-N 3.46Å; A175-L179 VanDerWaalsContact O-CB 3.31Å; A175-L179 WeakPolarHBondContact O-CB 3.29Å; A175-L179 WeakPolarHBondContact O-CD1 3.5Å; A175-L179 WeakPolarHBondContact O-CG 3.38Å; A175-L179 PolarHBondContact O-N 3.34Å; A175-M230 HydrophobicContact CB-CE 3.74Å; A175-M230 HydrophobicContact CB-SD 3.79Å
176E83.5Confident86Confident108 Ų10865.3 Ų65.351%0.50534%0.335SS..Hα-helixtrans-59.8-45.8175.8-179.9-174.3173.500112.2S174 E178 L179 S180 L185 L252S174-E176 VanDerWaalsContact C-N 3.3Å; S174-E176 PolarHBondContact OG-N 2.66Å; E176-E178 VanDerWaalsContact C-N 3.35Å; E176-E178 PolarHBondContact O-N 2.84Å; E176-L179 PolarHBondContact O-N 3.39Å; E176-S180 WeakPolarHBondContact O-CB 3.08Å; E176-S180 PolarHBondContact O-N 2.88Å; E176-L185 HydrophobicContact CG-CD2 3.9Å; E176-L252 HydrophobicContact CB-CD1 3.76Å; E176-L252 HydrophobicContact CG-CD1 3.96Å
177Q84Confident85.7Confident130 Ų13066.4 Ų66.461%0.60734%0.339SS*.Hα-helixtrans-64.7-40.7178.5-70.5178.9-27.400111.5S174 A175 S180 K181S174-Q177 PolarHBondContact O-N 2.89Å; S174-Q177 PolarHBondContact OG-N 3.48Å; A175-Q177 PolarHBondContact O-N 3.01Å; Q177-S180 PolarHBondContact O-N 2.91Å; Q177-K181 VanDerWaalsContact O-CB 3.23Å; Q177-K181 WeakPolarHBondContact O-CB 3.27Å; Q177-K181 PolarHBondContact O-N 2.96Å
178E85.9Confident85.4Confident54 Ų5464.1 Ų64.125%0.25233%0.333SS..Hα-helixtrans-68.1-41.8177.6-166.663.4-160.800111.4L67 L73 S174 A175 E176 S180 K181 T182L67-E178 HydrophobicContact CD2-CG 4.12Å; L73-E178 HydrophobicContact CD2-CB 3.56Å; L73-E178 HydrophobicContact CD2-CG 3.96Å; S174-E178 PolarHBondContact O-N 2.96Å; S174-E178 VanDerWaalsContact O-N 3.16Å; A175-E178 PolarHBondContact O-N 3.46Å; E176-E178 VanDerWaalsContact C-N 3.35Å; E176-E178 PolarHBondContact O-N 2.84Å; E178-S180 PolarHBondContact O-N 3.08Å; E178-K181 PolarHBondContact O-N 2.82Å; E178-T182 HydrophobicContact CG-CG2 4.43Å; E178-T182 WeakPolarHBondContact O-CB 3.42Å; E178-T182 WeakPolarHBondContact O-CG2 3.36Å; E178-T182 PolarHBondContact O-N 2.91Å; E178-T182 PolarHBondContact O-OG1 3.48Å
179L87.9Confident85.4Confident0 Ų063.7 Ų63.70%034%0.341CS..Hα-helixtrans-60.5-43.2174.5-74.7164.5000111.7L67 L75 A175 E176 T182 G183 W184 L185 M230 T233 V250 L252L67-L179 HydrophobicContact CD1-CD2 3.45Å; L67-L179 VanDerWaalsContact CD1-CD2 3.45Å; L67-L179 HydrophobicContact CD2-CD2 4.04Å; L67-L179 HydrophobicContact CD2-CG 4.48Å; L67-L179 HydrophobicContact CG-CD2 4.25Å; L75-L179 HydrophobicContact CD2-CD1 4.49Å; A175-L179 VanDerWaalsContact O-CB 3.31Å; A175-L179 WeakPolarHBondContact O-CB 3.29Å; A175-L179 WeakPolarHBondContact O-CD1 3.5Å; A175-L179 WeakPolarHBondContact O-CG 3.38Å; A175-L179 PolarHBondContact O-N 3.34Å; E176-L179 PolarHBondContact O-N 3.39Å; L179-T182 WeakPolarHBondContact CA-OG1 3.17Å; L179-T182 PolarHBondContact O-N 3.43Å; L179-T182 PolarHBondContact O-OG1 3.08Å; L179-G183 PolarHBondContact O-N 2.69Å; L179-W184 HydrophobicContact CD2-CB 3.72Å; L179-W184 PolarHBondContact O-N 2.82Å; L179-L185 HydrophobicContact CB-CB 3.95Å; L179-L185 PolarHBondContact O-N 3.03Å; L179-L185 VanDerWaalsContact O-N 3.09Å; L179-M230 HydrophobicContact CD1-SD 4.42Å; L179-T233 HydrophobicContact CD2-CG2 4.34Å; L179-V250 HydrophobicContact CD1-CG2 3.76Å; L179-V250 HydrophobicContact CD2-CG2 3.68Å; L179-V250 HydrophobicContact CG-CG2 4.22Å; L179-L252 HydrophobicContact CD1-CD1 3.99Å
180S86.9Confident85.6Confident70 Ų7062.9 Ų62.949%0.4934%0.338SS..Hα-helixtrans-64-49.1175.2-179.90000111.3E176 Q177 E178 T182 G183E176-S180 WeakPolarHBondContact O-CB 3.08Å; E176-S180 PolarHBondContact O-N 2.88Å; Q177-S180 PolarHBondContact O-N 2.91Å; E178-S180 PolarHBondContact O-N 3.08Å; S180-T182 VanDerWaalsContact C-N 3.3Å; S180-T182 PolarHBondContact O-N 2.73Å; S180-G183 PolarHBondContact O-N 3.06Å; S180-G183 VanDerWaalsContact O-N 3.09Å
181K85.3Confident86Confident131 Ų13155.4 Ų55.457%0.5730%0.303SS*.Hα-helixtrans-59.4-39.6177.6-178.6-172169.1-1590112R62 Q177 E178 G183R62-K181 PolarHBondContact NH1-O 3.28Å; R62-K181 PolarHBondContact NH2-O 3.08Å; Q177-K181 VanDerWaalsContact O-CB 3.23Å; Q177-K181 WeakPolarHBondContact O-CB 3.27Å; Q177-K181 PolarHBondContact O-N 2.96Å; E178-K181 PolarHBondContact O-N 2.82Å; K181-G183 VanDerWaalsContact C-N 3.32Å
182T86.9Confident86.8Confident4 Ų457.7 Ų57.73%0.02530%0.299CS..Hα-helixtrans-83.3-8-179.850.70000113.2R64 E65 L67 E178 L179 S180 W184R64-T182 WeakPolarHBondContact CG-O 3.48Å; E65-T182 HydrophobicContact CB-CG2 4.46Å; L67-T182 HydrophobicContact CD2-CG2 4.49Å; E178-T182 HydrophobicContact CG-CG2 4.43Å; E178-T182 WeakPolarHBondContact O-CB 3.42Å; E178-T182 WeakPolarHBondContact O-CG2 3.36Å; E178-T182 PolarHBondContact O-N 2.91Å; E178-T182 PolarHBondContact O-OG1 3.48Å; L179-T182 WeakPolarHBondContact CA-OG1 3.17Å; L179-T182 PolarHBondContact O-N 3.43Å; L179-T182 PolarHBondContact O-OG1 3.08Å; S180-T182 VanDerWaalsContact C-N 3.3Å; S180-T182 PolarHBondContact O-N 2.73Å; T182-W184 VanDerWaalsContact OG1-CD1 3.31Å
183G86.8Confident87.6Confident14 Ų1460.7 Ų60.714%0.14431%0.311CS..THydrogen-bonded Turntrans78.524.6178.800000113.6R64 L179 S180 K181R64-G183 PolarHBondContact NE-O 3.27Å; R64-G183 PolarHBondContact NH2-O 2.89Å; L179-G183 PolarHBondContact O-N 2.69Å; S180-G183 PolarHBondContact O-N 3.06Å; S180-G183 VanDerWaalsContact O-N 3.09Å; K181-G183 VanDerWaalsContact C-N 3.32Å
184W91.4Very high88.3Confident8 Ų857 Ų573%0.0331%0.307CS..  trans-97.7-20.3174.3-67.4107.3000112.9R64 E65 L179 T182 L186 T237 L247 G249 V250R64-W184 HydrophobicContact CG-CZ2 4.1Å; E65-W184 PolarHBondContact O-NE1 3.09Å; L179-W184 HydrophobicContact CD2-CB 3.72Å; L179-W184 PolarHBondContact O-N 2.82Å; T182-W184 VanDerWaalsContact OG1-CD1 3.31Å; W184-L186 PolarHBondContact O-N 2.93Å; W184-T237 HydrophobicContact CD2-CG2 3.45Å; W184-T237 VanDerWaalsContact CD2-CG2 3.45Å; W184-T237 HydrophobicContact CE3-CG2 3.9Å; W184-T237 HydrophobicContact CG-CG2 3.81Å; W184-T237 HydrophobicContact CH2-CG2 4.19Å; W184-T237 HydrophobicContact CZ2-CG2 3.77Å; W184-T237 HydrophobicContact CZ3-CG2 4.24Å; W184-L247 HydrophobicContact CE3-CD2 3.68Å; W184-L247 HydrophobicContact CE3-CG 4.07Å; W184-L247 HydrophobicContact CZ3-CB 4.19Å; W184-L247 HydrophobicContact CZ3-CD2 3.67Å; W184-L247 HydrophobicContact CZ3-CG 3.84Å; W184-G249 CarbonylContact O-C 3.49Å; W184-G249 VanDerWaalsContact O-CA 3.3Å; W184-G249 WeakPolarHBondContact O-CA 3.27Å; W184-V250 PolarHBondContact O-N 3.46Å
185L90.3Very high88.8Confident47 Ų4761.9 Ų61.925%0.24633%0.326CS..BIsolated β-bridgetrans-75.6119172.7-168.965.5000110.3E176 L179 L252E176-L185 HydrophobicContact CG-CD2 3.9Å; L179-L185 HydrophobicContact CB-CB 3.95Å; L179-L185 PolarHBondContact O-N 3.03Å; L179-L185 VanDerWaalsContact O-N 3.09Å; L185-L252 HydrophobicContact CD1-CB 4.14Å; L185-L252 HydrophobicContact CD1-CD1 3.83Å; L185-L252 HydrophobicContact CD1-CG 3.68Å
186L90.9Very high89.3Confident23 Ų2365.6 Ų65.612%0.1235%0.346CS..  trans-94.6153.3177.4-58.3-178.1000110.9W184 Y210 V250 I251 V259W184-L186 PolarHBondContact O-N 2.93Å; L186-Y210 HydrophobicContact CB-CE2 3.84Å; L186-Y210 HydrophobicContact CD1-CE1 4.33Å; L186-Y210 HydrophobicContact CD1-CE2 4.29Å; L186-Y210 HydrophobicContact CD2-CE1 4.04Å; L186-Y210 HydrophobicContact CG-CE2 4.49Å; L186-V250 PolarHBondContact N-O 2.94Å; L186-I251 HydrophobicContact CB-CD1 4.31Å; L186-I251 HydrophobicContact CB-CG1 3.69Å; L186-V259 HydrophobicContact CD1-CB 3.85Å; L186-V259 HydrophobicContact CD1-CG1 4.13Å; L186-V259 HydrophobicContact CD1-CG2 3.94Å
187D87.9Confident89.6Confident68 Ų6864.3 Ų64.336%0.36434%0.342SS..  trans-85.8112.5179.5-177.9-9.5000110.2T189 K190 Y210D187-T189 PolarHBondContact O-N 3.31Å; D187-T189 VanDerWaalsContact O-N 3.12Å; D187-T189 WeakPolarHBondContact OD1-CB 3.47Å; D187-T189 WeakPolarHBondContact OD1-CG2 3.46Å; D187-T189 PolarHBondContact OD1-N 2.87Å; D187-T189 PolarHBondContact OD1-OG1 2.96Å; D187-T189 PolarHBondContact OD2-OG1 3.23Å; D187-K190 HydrophobicContact CB-CD 4.16Å; D187-K190 HydrophobicContact CB-CG 4.1Å; D187-K190 PolarHBondContact O-N 2.71Å; D187-Y210 PolarHBondContact N-OH 3.37Å; D187-Y210 WeakPolarHBondContact O-CE2 3.3Å
188I88.9Confident89.6Confident51 Ų5159.4 Ų59.426%0.26233%0.326SS..G310 helixtrans-55.8-30.5-179.5-174.263.3000112.9K190 L191 I251 H253I188-K190 PolarHBondContact O-N 3.27Å; I188-K190 VanDerWaalsContact O-N 3.12Å; I188-L191 HydrophobicContact CD1-CB 4.31Å; I188-L191 HydrophobicContact CD1-CD2 3.99Å; I188-L191 PolarHBondContact O-N 2.95Å; I188-I251 HydrophobicContact CB-CG2 3.77Å; I188-I251 HydrophobicContact CD1-CD1 4.23Å; I188-I251 HydrophobicContact CD1-CG2 3.76Å; I188-I251 HydrophobicContact CG1-CG2 4.19Å; I188-H253 HydrophobicContact CB-CB 3.97Å; I188-H253 HydrophobicContact CD1-CB 4.45Å; I188-H253 HydrophobicContact CG1-CB 3.94Å; I188-H253 HydrophobicContact CG2-CB 4.05Å
189T88.9Confident89.3Confident117 Ų11763.5 Ų63.572%0.71835%0.345SS*.G310 helixtrans-66.7-16.2-178.167.10000113D187D187-T189 PolarHBondContact O-N 3.31Å; D187-T189 VanDerWaalsContact O-N 3.12Å; D187-T189 WeakPolarHBondContact OD1-CB 3.47Å; D187-T189 WeakPolarHBondContact OD1-CG2 3.46Å; D187-T189 PolarHBondContact OD1-N 2.87Å; D187-T189 PolarHBondContact OD1-OG1 2.96Å; D187-T189 PolarHBondContact OD2-OG1 3.23Å
190K89.5Confident88.3Confident86 Ų8665.7 Ų65.737%0.37437%0.368SS..G310 helixtrans-96.7-1.3177.4-53.9-173.1-176.8-1760113.3D187 I188 Y210 M211D187-K190 HydrophobicContact CB-CD 4.16Å; D187-K190 HydrophobicContact CB-CG 4.1Å; D187-K190 PolarHBondContact O-N 2.71Å; I188-K190 PolarHBondContact O-N 3.27Å; I188-K190 VanDerWaalsContact O-N 3.12Å; K190-Y210 HydrophobicContact CB-CD2 4.2Å; K190-Y210 HydrophobicContact CB-CE2 3.78Å; K190-M211 HydrophobicContact CB-CG 3.91Å; K190-M211 HydrophobicContact CD-CG 3.66Å; K190-M211 HydrophobicContact CD-SD 3.55Å; K190-M211 VanDerWaalsContact CD-SD 3.55Å; K190-M211 HydrophobicContact CG-CG 4.37Å; K190-M211 PolarHBondContact O-N 2.99Å
191L92.7Very high87.1Confident22 Ų2269.6 Ų69.612%0.11538%0.379CS..EExtended strand (participates in β ladder)trans-97.3125.9176.7179.568.4000110.2I188 L193 E209 Y210 V215 V217 I251I188-L191 HydrophobicContact CD1-CB 4.31Å; I188-L191 HydrophobicContact CD1-CD2 3.99Å; I188-L191 PolarHBondContact O-N 2.95Å; L191-L193 HydrophobicContact CD2-CD1 4.4Å; L191-E209 WeakPolarHBondContact CA-O 3.44Å; L191-Y210 HydrophobicContact CB-CD2 4.15Å; L191-V215 HydrophobicContact CD1-CG2 4.01Å; L191-V217 HydrophobicContact CD1-CG2 3.96Å; L191-V217 HydrophobicContact CD2-CG1 4.43Å; L191-V217 HydrophobicContact CD2-CG2 4.15Å; L191-I251 HydrophobicContact CB-CD1 4.17Å; L191-I251 HydrophobicContact CD2-CD1 3.6Å; L191-I251 HydrophobicContact CG-CD1 4.4Å
192I94.6Very high86.1Confident112 Ų11266.8 Ų66.857%0.57437%0.366SS*.EExtended strand (participates in β ladder)trans-103.3109.8165-56173.4000107G208 E209I192-G208 CarbonylContact O-C 3.56Å; I192-G208 WeakPolarHBondContact O-CA 3.19Å; I192-E209 HydrophobicContact CB-CB 4.44Å; I192-E209 PolarHBondContact N-O 3.48Å; I192-E209 PolarHBondContact O-N 3.11Å
193L93.1Very high85.6Confident87 Ų8766.7 Ų66.746%0.45537%0.367SS..EExtended strand (participates in β ladder)trans-80.5132.1177.2-162.470.3000109.8L191 Y206 V217L191-L193 HydrophobicContact CD2-CD1 4.4Å; L193-Y206 HydrophobicContact CD1-CD2 4.49Å; L193-Y206 HydrophobicContact CD1-CG 4.03Å; L193-Y206 HydrophobicContact CD2-CD1 4.33Å; L193-Y206 HydrophobicContact CD2-CG 4.24Å; L193-Y206 HydrophobicContact CG-CD1 4.4Å; L193-Y206 HydrophobicContact CG-CG 4.21Å; L193-V217 HydrophobicContact CD1-CB 3.94Å; L193-V217 HydrophobicContact CD1-CG1 4.11Å; L193-V217 HydrophobicContact CD1-CG2 4.04Å
194G93.6Very high85.4Confident39 Ų3966.2 Ų66.240%0.40236%0.361SS..EExtended strand (participates in β ladder)trans-108.9-146.9178.600000112.6R207G194-R207 CarbonylContact C-O 3.56Å; G194-R207 WeakPolarHBondContact CA-O 3.37Å; G194-R207 PolarHBondContact N-O 2.91Å
195E93.3Very high85.3Confident129 Ų12967.8 Ų67.860%0.60337%0.372SS*.EExtended strand (participates in β ladder)trans-70.6155-175.970.7-158161.500113.7I197 Y206 R207E195-I197 HydrophobicContact CG-CG2 4Å; E195-I197 PolarHBondContact O-N 3.25Å; E195-Y206 CarbonylContact O-C 3.47Å; E195-Y206 VanDerWaalsContact O-CA 3.32Å; E195-Y206 WeakPolarHBondContact O-CA 3.43Å; E195-R207 HydrophobicContact CG-CB 4.28Å; E195-R207 PolarHBondContact O-N 2.8Å
196N92.8Very high85.5Confident78 Ų7868.6 Ų68.642%0.41737%0.372SS..EExtended strand (participates in β ladder)trans-72.6123.6170.4-176-27.9000109.2G198 V205 Y206N196-G198 PolarHBondContact OD1-N 2.76Å; N196-G198 PolarHBondContact OD1-O 2.77Å; N196-V205 PolarHBondContact OD1-O 3.02Å; N196-Y206 HydrophobicContact CB-CD1 3.99Å; N196-Y206 HydrophobicContact CB-CE1 3.8Å
197I90.6Very high85.7Confident81 Ų8172.2 Ų72.242%0.41538%0.384SS..EExtended strand (participates in β ladder)trans-110.3-1.8-178.958.5170.3000113.1E195 V205 R207 L262E195-I197 HydrophobicContact CG-CG2 4Å; E195-I197 PolarHBondContact O-N 3.25Å; I197-V205 HydrophobicContact CD1-CG1 4.01Å; I197-V205 HydrophobicContact CG1-CB 4.27Å; I197-V205 HydrophobicContact CG1-CG1 3.93Å; I197-V205 VanDerWaalsContact CG1-O 3.28Å; I197-V205 WeakPolarHBondContact CG1-O 3.43Å; I197-V205 PolarHBondContact N-O 3.17Å; I197-R207 HydrophobicContact CD1-CB 4.47Å; I197-R207 HydrophobicContact CG2-CB 3.77Å; I197-L262 HydrophobicContact CD1-CD1 3.88Å
198G83.5Confident86.1Confident27 Ų2769 Ų6928%0.27837%0.367SS..EExtended strand (participates in β ladder)trans178.6148.9177.200000112.7N196 A204 V205N196-G198 PolarHBondContact OD1-N 2.76Å; N196-G198 PolarHBondContact OD1-O 2.77Å; G198-A204 CarbonylContact O-C 3.54Å; G198-V205 PolarHBondContact N-O 3.23Å; G198-V205 PolarHBondContact O-N 3.1Å
199E79.8Confident86.3Confident139 Ų13970.4 Ų70.465%0.6537%0.373SS*.EExtended strand (participates in β ladder)trans-129.9132.2171.7-172.3165.1-156.900109.1K221E199-K221 IonicContact OE1-NZ 2.68Å; E199-K221 PolarHBondContact OE1-NZ 3.04Å
200G66.4Low86.4Confident46 Ų4666.3 Ų66.347%0.47434%0.344SS..EExtended strand (participates in β ladder)trans-136.5-176.9-179.700000112.2F202 G203G200-F202 PolarHBondContact O-N 3.45Å; G200-G203 PolarHBondContact N-O 3.35Å; G200-G203 PolarHBondContact O-N 2.99Å; G200-G203 VanDerWaalsContact O-N 3.14Å
201E62.1Low86.2Confident153 Ų15365.7 Ų65.772%0.71534%0.344SS*.THydrogen-bonded Turntrans-57.1-34-179.1-173.5173-177.500112.5
202F64.6Low85.7Confident71 Ų7167.3 Ų67.331%0.31137%0.366SS..THydrogen-bonded Turntrans-91.1-3.6-176.1-54.7-69.8000114.2G200 K221G200-F202 PolarHBondContact O-N 3.45Å; F202-K221 PolarHBondContact O-N 2.74Å
203G74.9Confident85.3Confident3 Ų363.9 Ų63.93%0.03135%0.347CS..EExtended strand (participates in β ladder)trans133-167.3177.400000114G200 T219G200-G203 PolarHBondContact N-O 3.35Å; G200-G203 PolarHBondContact O-N 2.99Å; G200-G203 VanDerWaalsContact O-N 3.14Å; G203-T219 WeakPolarHBondContact CA-O 3.15Å
204A83.8Confident85.3Confident3 Ų362.4 Ų62.43%0.02534%0.339CS..EExtended strand (participates in β ladder)trans-94147.5-178.700000111G198 Y206 T219G198-A204 CarbonylContact O-C 3.54Å; A204-Y206 HydrophobicContact CB-CD2 4.38Å; A204-Y206 HydrophobicContact CB-CE2 3.58Å; A204-T219 PolarHBondContact O-N 3.04Å; A204-T219 PolarHBondContact O-OG1 3.14Å
205V90.2Very high85.4Confident42 Ų4260.6 Ų60.626%0.25532%0.32SS..EExtended strand (participates in β ladder)trans-114.9125.3176-172.60000107.8N196 I197 G198 A216 V217 K218N196-V205 PolarHBondContact OD1-O 3.02Å; I197-V205 HydrophobicContact CD1-CG1 4.01Å; I197-V205 HydrophobicContact CG1-CB 4.27Å; I197-V205 HydrophobicContact CG1-CG1 3.93Å; I197-V205 VanDerWaalsContact CG1-O 3.28Å; I197-V205 WeakPolarHBondContact CG1-O 3.43Å; I197-V205 PolarHBondContact N-O 3.17Å; G198-V205 PolarHBondContact N-O 3.23Å; G198-V205 PolarHBondContact O-N 3.1Å; V205-A216 HydrophobicContact CG1-CB 4.28Å; V205-V217 CarbonylContact C-O 3.57Å; V205-V217 WeakPolarHBondContact CA-O 3.49Å; V205-K218 HydrophobicContact CG2-CB 4.28Å; V205-K218 HydrophobicContact CG2-CG 4.19Å
206Y93.2Very high85.5Confident64 Ų6454.9 Ų54.925%0.25130%0.295SS..EExtended strand (participates in β ladder)trans-112.1146.8179.7-63.4-94.4000110.4L193 E195 N196 A204 A216 V217 T219L193-Y206 HydrophobicContact CD1-CD2 4.49Å; L193-Y206 HydrophobicContact CD1-CG 4.03Å; L193-Y206 HydrophobicContact CD2-CD1 4.33Å; L193-Y206 HydrophobicContact CD2-CG 4.24Å; L193-Y206 HydrophobicContact CG-CD1 4.4Å; L193-Y206 HydrophobicContact CG-CG 4.21Å; E195-Y206 CarbonylContact O-C 3.47Å; E195-Y206 VanDerWaalsContact O-CA 3.32Å; E195-Y206 WeakPolarHBondContact O-CA 3.43Å; N196-Y206 HydrophobicContact CB-CD1 3.99Å; N196-Y206 HydrophobicContact CB-CE1 3.8Å; A204-Y206 HydrophobicContact CB-CD2 4.38Å; A204-Y206 HydrophobicContact CB-CE2 3.58Å; Y206-A216 CarbonylContact O-C 3.55Å; Y206-A216 WeakPolarHBondContact O-CA 3.29Å; Y206-V217 PolarHBondContact N-O 2.9Å; Y206-V217 PolarHBondContact O-N 2.8Å; Y206-T219 HydrophobicContact CE2-CG2 4.48Å; Y206-T219 WeakPolarHBondContact CE2-OG1 3.25Å
207R95.6Very high85.5Confident98 Ų9851.1 Ų51.137%0.3728%0.275SS..EExtended strand (participates in β ladder)trans-71.1142.6160.1-174.5178.6-173.5-80.5-0.4107.8G194 E195 I197 M214 L262G194-R207 CarbonylContact C-O 3.56Å; G194-R207 WeakPolarHBondContact CA-O 3.37Å; G194-R207 PolarHBondContact N-O 2.91Å; E195-R207 HydrophobicContact CG-CB 4.28Å; E195-R207 PolarHBondContact O-N 2.8Å; I197-R207 HydrophobicContact CD1-CB 4.47Å; I197-R207 HydrophobicContact CG2-CB 3.77Å; R207-M214 HydrophobicContact CG-CE 3.57Å; R207-M214 PolarHBondContact NH2-SD 2.98Å; R207-L262 HydrophobicContact CG-CD2 4.13Å
208G95.6Very high85.4Confident2 Ų248.8 Ų48.82%0.02126%0.261CS..EExtended strand (participates in β ladder)trans-153.5173.3173.600000112.1I192 M214 V215I192-G208 CarbonylContact O-C 3.56Å; I192-G208 WeakPolarHBondContact O-CA 3.19Å; G208-M214 WeakPolarHBondContact O-CE 3.43Å; G208-V215 PolarHBondContact N-O 3.43Å; G208-V215 WeakPolarHBondContact O-CG2 3.47Å; G208-V215 PolarHBondContact O-N 3.35Å
209E94Very high85.4Confident80 Ų8048.9 Ų48.937%0.37426%0.257SS..EExtended strand (participates in β ladder)trans-124.2126173.5-171.5-173135.100108.9L191 I192 G212 Q213 M214L191-E209 WeakPolarHBondContact CA-O 3.44Å; I192-E209 HydrophobicContact CB-CB 4.44Å; I192-E209 PolarHBondContact N-O 3.48Å; I192-E209 PolarHBondContact O-N 3.11Å; E209-G212 VanDerWaalsContact OE1-CA 3.32Å; E209-G212 WeakPolarHBondContact OE1-CA 3.31Å; E209-Q213 CarbonylContact C-O 3.49Å; E209-Q213 WeakPolarHBondContact CA-O 3.27Å; E209-M214 HydrophobicContact CB-SD 4.42Å
210Y91Very high85.2Confident30 Ų3043 Ų4312%0.11823%0.23CC..EExtended strand (participates in β ladder)trans-121.2113.5176.7-175-95.4000109.3L186 D187 K190 L191 G212 Q213L186-Y210 HydrophobicContact CB-CE2 3.84Å; L186-Y210 HydrophobicContact CD1-CE1 4.33Å; L186-Y210 HydrophobicContact CD1-CE2 4.29Å; L186-Y210 HydrophobicContact CD2-CE1 4.04Å; L186-Y210 HydrophobicContact CG-CE2 4.49Å; D187-Y210 PolarHBondContact N-OH 3.37Å; D187-Y210 WeakPolarHBondContact O-CE2 3.3Å; K190-Y210 HydrophobicContact CB-CD2 4.2Å; K190-Y210 HydrophobicContact CB-CE2 3.78Å; L191-Y210 HydrophobicContact CB-CD2 4.15Å; Y210-G212 VanDerWaalsContact C-N 3.29Å; Y210-G212 PolarHBondContact O-N 2.72Å; Y210-Q213 PolarHBondContact N-O 2.72Å; Y210-Q213 PolarHBondContact O-N 2.75Å
211M85.6Confident85.2Confident73 Ų7346.1 Ų46.136%0.3623%0.23SC..THydrogen-bonded Turntrans50.644-177.9-62.3-177.157.300113.6K190 Q213K190-M211 HydrophobicContact CB-CG 3.91Å; K190-M211 HydrophobicContact CD-CG 3.66Å; K190-M211 HydrophobicContact CD-SD 3.55Å; K190-M211 VanDerWaalsContact CD-SD 3.55Å; K190-M211 HydrophobicContact CG-CG 4.37Å; K190-M211 PolarHBondContact O-N 2.99Å; M211-Q213 VanDerWaalsContact C-N 3.25Å; M211-Q213 PolarHBondContact O-N 3.27Å
212G81.7Confident84.9Confident57 Ų5740 Ų4059%0.58820%0.204SC*.THydrogen-bonded Turntrans82.6-9.5-179.200000115.2E209 Y210E209-G212 VanDerWaalsContact OE1-CA 3.32Å; E209-G212 WeakPolarHBondContact OE1-CA 3.31Å; Y210-G212 VanDerWaalsContact C-N 3.29Å; Y210-G212 PolarHBondContact O-N 2.72Å
213Q86.5Confident84.2Confident39 Ų3937.3 Ų37.318%0.18219%0.193CC..EExtended strand (participates in β ladder)trans-95.5133.5177.1173.2167.922.700111.3T49 E209 Y210 M211 V215T49-Q213 HydrophobicContact CG2-CB 3.75Å; T49-Q213 PolarHBondContact OG1-OE1 3.17Å; E209-Q213 CarbonylContact C-O 3.49Å; E209-Q213 WeakPolarHBondContact CA-O 3.27Å; Y210-Q213 PolarHBondContact N-O 2.72Å; Y210-Q213 PolarHBondContact O-N 2.75Å; M211-Q213 VanDerWaalsContact C-N 3.25Å; M211-Q213 PolarHBondContact O-N 3.27Å; Q213-V215 HydrophobicContact CG-CG1 4.34Å
214M92.9Very high83.1Confident57 Ų5742.8 Ų42.828%0.28123%0.225SC..EExtended strand (participates in β ladder)trans-68.6129.6172.4-71.5-53.8-40.400111.8R207 G208 E209 L262R207-M214 HydrophobicContact CG-CE 3.57Å; R207-M214 PolarHBondContact NH2-SD 2.98Å; G208-M214 WeakPolarHBondContact O-CE 3.43Å; E209-M214 HydrophobicContact CB-SD 4.42Å; M214-L262 HydrophobicContact CB-CB 4.37Å; M214-L262 HydrophobicContact CB-CD2 3.97Å; M214-L262 HydrophobicContact CE-CD2 3.77Å
215V95Very high82Confident0 Ų044 Ų440%023%0.232CC..EExtended strand (participates in β ladder)trans-133.7159-175.5-58.10000112.4L191 G208 Q213 V217 L248 V259 T260L191-V215 HydrophobicContact CD1-CG2 4.01Å; G208-V215 PolarHBondContact N-O 3.43Å; G208-V215 WeakPolarHBondContact O-CG2 3.47Å; G208-V215 PolarHBondContact O-N 3.35Å; Q213-V215 HydrophobicContact CG-CG1 4.34Å; V215-V217 HydrophobicContact CG2-CG2 3.94Å; V215-L248 HydrophobicContact CB-CD1 4.18Å; V215-L248 HydrophobicContact CG1-CD1 3.31Å; V215-V259 HydrophobicContact CB-CG1 3.75Å; V215-V259 HydrophobicContact CG1-CG1 3.99Å; V215-V259 HydrophobicContact CG2-CG1 3.88Å; V215-T260 WeakPolarHBondContact CA-O 3.28Å; V215-T260 WeakPolarHBondContact CB-O 3.43Å
216A95.1Very high80.8Confident9 Ų942.4 Ų42.47%0.07422%0.224CC..EExtended strand (participates in β ladder)trans-104.2134.1163.700000109.3V205 Y206 V259 T260 L262V205-A216 HydrophobicContact CG1-CB 4.28Å; Y206-A216 CarbonylContact O-C 3.55Å; Y206-A216 WeakPolarHBondContact O-CA 3.29Å; A216-V259 WeakPolarHBondContact O-CA 3.42Å; A216-T260 PolarHBondContact N-O 3.28Å; A216-T260 PolarHBondContact O-N 2.93Å; A216-L262 HydrophobicContact CB-CD1 4.07Å
217V93.4Very high79.6Confident0 Ų046 Ų460%024%0.243CC..EExtended strand (participates in β ladder)trans-118.8102.9-177.3-174.10000108.9L191 L193 V205 Y206 V215 H257 V259L191-V217 HydrophobicContact CD1-CG2 3.96Å; L191-V217 HydrophobicContact CD2-CG1 4.43Å; L191-V217 HydrophobicContact CD2-CG2 4.15Å; L193-V217 HydrophobicContact CD1-CB 3.94Å; L193-V217 HydrophobicContact CD1-CG1 4.11Å; L193-V217 HydrophobicContact CD1-CG2 4.04Å; V205-V217 CarbonylContact C-O 3.57Å; V205-V217 WeakPolarHBondContact CA-O 3.49Å; Y206-V217 PolarHBondContact N-O 2.9Å; Y206-V217 PolarHBondContact O-N 2.8Å; V215-V217 HydrophobicContact CG2-CG2 3.94Å; V217-H257 HydrophobicContact CG1-CB 4.02Å; V217-V259 HydrophobicContact CG2-CG2 4.49Å
218K88.9Confident78.4Confident31 Ų3143.2 Ų43.214%0.13524%0.241CC..EExtended strand (participates in β ladder)trans-86.4110.1174.4-176.5-179.5176.7-172.10108.6V205 I220 E232 H257 I258 D326V205-K218 HydrophobicContact CG2-CB 4.28Å; V205-K218 HydrophobicContact CG2-CG 4.19Å; K218-I220 HydrophobicContact CD-CD1 4.08Å; K218-I220 HydrophobicContact CG-CD1 3.91Å; K218-E232 IonicContact NZ-OE1 3.11Å; K218-E232 PolarHBondContact NZ-OE1 3.11Å; K218-E232 IonicContact NZ-OE2 3.39Å; K218-H257 WeakPolarHBondContact O-CA 3.29Å; K218-I258 HydrophobicContact CB-CB 4.37Å; K218-I258 PolarHBondContact N-O 3.1Å; K218-I258 PolarHBondContact O-N 2.97Å; K218-D326 IonicContact NZ-OD1 2.8Å; K218-D326 PolarHBondContact NZ-OD1 2.92Å
219T84.1Confident77.6Confident29 Ų2943.1 Ų43.118%0.17824%0.24CC..EExtended strand (participates in β ladder)trans-80.4128.4169.7310000110.3G203 A204 Y206 H257G203-T219 WeakPolarHBondContact CA-O 3.15Å; A204-T219 PolarHBondContact O-N 3.04Å; A204-T219 PolarHBondContact O-OG1 3.14Å; Y206-T219 HydrophobicContact CE2-CG2 4.48Å; Y206-T219 WeakPolarHBondContact CE2-OG1 3.25Å; T219-H257 WeakPolarHBondContact CG2-CD2 3.34Å; T219-H257 WeakPolarHBondContact CG2-NE2 3.41Å
220I75.6Confident76.8Confident17 Ų1740.3 Ų40.39%0.08723%0.227CC..EExtended strand (participates in β ladder)trans-95.8124.8177.4-49.8-58.4000109.7K218 T225 F229 L256 I258K218-I220 HydrophobicContact CD-CD1 4.08Å; K218-I220 HydrophobicContact CG-CD1 3.91Å; I220-T225 HydrophobicContact CG2-CG2 3.79Å; I220-T225 WeakPolarHBondContact CG2-OG1 3.42Å; I220-F229 HydrophobicContact CG1-CD2 3.87Å; I220-L256 HydrophobicContact CB-CB 4.23Å; I220-L256 PolarHBondContact N-O 3.31Å; I220-I258 HydrophobicContact CD1-CD1 4.15Å; I220-I258 HydrophobicContact CG1-CD1 4.45Å; I220-I258 HydrophobicContact CG1-CG1 4.48Å
221K65.1Low76Confident111 Ų11143.5 Ų43.548%0.48324%0.243SC..PPolyproline II helixtrans-87.1133.6178.5-63.6179.5-177.3173.20110.8E199 F202 T225E199-K221 IonicContact OE1-NZ 2.68Å; E199-K221 PolarHBondContact OE1-NZ 3.04Å; F202-K221 PolarHBondContact O-N 2.74Å; K221-T225 WeakPolarHBondContact O-CG2 3.34Å
222C55.6Low75.7Confident23 Ų2340.7 Ų40.716%0.15523%0.229CC..SBendtrans77148.2159.7-156.60000121.1Y129 V224 T225Y129-C222 WeakPolarHBondContact CE2-SG 3.37Å; Y129-C222 PolarHBondContact OH-SG 3.44Å; C222-V224 PolarHBondContact O-N 3.13Å; C222-V224 VanDerWaalsContact O-N 3.11Å; C222-T225 VanDerWaalsContact O-CB 3.29Å; C222-T225 WeakPolarHBondContact O-CB 3.38Å; C222-T225 WeakPolarHBondContact O-CG2 3.29Å; C222-T225 PolarHBondContact O-N 2.99Å; C222-T225 PolarHBondContact O-OG1 2.99Å
223D51.3Low75.7Confident15 Ų1538 Ų388%0.0820%0.201CC..THydrogen-bonded Turntrans-63.5-12.2-167.9-73.9-64.3000119.6L134 N144 L145 T225L134-D223 WeakPolarHBondContact CD1-OD2 3.26Å; N144-D223 WeakPolarHBondContact CA-OD2 3.45Å; L145-D223 VanDerWaalsContact CB-OD1 3.27Å; L145-D223 WeakPolarHBondContact CB-OD1 3.36Å; L145-D223 HydrophobicContact CD1-CB 4.14Å; L145-D223 HydrophobicContact CG-CB 4.39Å; L145-D223 VanDerWaalsContact CG-CG 3.47Å; L145-D223 VanDerWaalsContact CG-OD2 3.3Å; L145-D223 WeakPolarHBondContact CG-OD2 3.36Å; L145-D223 PolarHBondContact N-OD1 3.1Å; L145-D223 PolarHBondContact N-OD2 3.12Å; D223-T225 PolarHBondContact O-N 3.42Å
224V51.7Low75.5Confident118 Ų11836.3 Ų36.372%0.71519%0.194SC*.THydrogen-bonded Turntrans-77.7-8.7171.7-155.70000110.8C222C222-V224 PolarHBondContact O-N 3.13Å; C222-V224 VanDerWaalsContact O-N 3.11Å
225T59.4Low75.1Confident28 Ų2834.3 Ų34.317%0.17219%0.185CC..Hα-helixtrans-97.6-11-173.567.50000115.3I220 K221 C222 D223 Q227 A228 F229I220-T225 HydrophobicContact CG2-CG2 3.79Å; I220-T225 WeakPolarHBondContact CG2-OG1 3.42Å; K221-T225 WeakPolarHBondContact O-CG2 3.34Å; C222-T225 VanDerWaalsContact O-CB 3.29Å; C222-T225 WeakPolarHBondContact O-CB 3.38Å; C222-T225 WeakPolarHBondContact O-CG2 3.29Å; C222-T225 PolarHBondContact O-N 2.99Å; C222-T225 PolarHBondContact O-OG1 2.99Å; D223-T225 PolarHBondContact O-N 3.42Å; T225-Q227 PolarHBondContact O-N 2.85Å; T225-A228 CarbonylContact O-C 3.46Å; T225-A228 PolarHBondContact O-N 2.89Å; T225-F229 WeakPolarHBondContact O-CB 3.5Å; T225-F229 PolarHBondContact O-N 2.84Å
226A65.3Low74.8Confident9 Ų934.8 Ų34.87%0.07419%0.187CC..Hα-helixtrans-58.2-38.5179.400000111.6L75 M76 M230 L256L75-A226 HydrophobicContact CB-CB 4.39Å; L75-A226 HydrophobicContact CD1-CB 4.03Å; M76-A226 HydrophobicContact CE-CB 3.9Å; A226-M230 WeakPolarHBondContact O-CB 3.19Å; A226-M230 VanDerWaalsContact O-CG 3.23Å; A226-M230 WeakPolarHBondContact O-CG 3.4Å; A226-M230 PolarHBondContact O-N 2.88Å; A226-L256 HydrophobicContact CB-CD1 4.23Å
227Q68.9Low74.4Confident140 Ų14035 Ų3565%0.65419%0.188SC*.Hα-helixtrans-70.8-41.5174.3-172.5171.2-6.100112.2T225 M230 Q231T225-Q227 PolarHBondContact O-N 2.85Å; Q227-M230 PolarHBondContact O-N 2.55Å; Q227-Q231 WeakPolarHBondContact O-CB 3.41Å; Q227-Q231 VanDerWaalsContact O-CG 3.26Å; Q227-Q231 WeakPolarHBondContact O-CG 3.38Å; Q227-Q231 PolarHBondContact O-N 3.02Å
228A70.3Confident74.1Confident39 Ų3938.4 Ų38.432%0.32220%0.202SC..Hα-helixtrans-63.6-43.5176.200000111.7T225 Q231 E232T225-A228 CarbonylContact O-C 3.46Å; T225-A228 PolarHBondContact O-N 2.89Å; A228-Q231 WeakPolarHBondContact O-CB 3.26Å; A228-Q231 PolarHBondContact O-N 2.85Å; A228-E232 WeakPolarHBondContact O-CB 3.47Å; A228-E232 PolarHBondContact O-N 2.98Å
229F77.7Confident74Confident1 Ų137.8 Ų37.80%0.00420%0.2CC..Hα-helixtrans-58.8-47.1171.9169-89.9000111.1L75 I220 T225 Q231 E232 T233 V250 L252 L256 I258L75-F229 HydrophobicContact CD1-CD1 3.58Å; L75-F229 HydrophobicContact CD1-CE1 3.86Å; I220-F229 HydrophobicContact CG1-CD2 3.87Å; T225-F229 WeakPolarHBondContact O-CB 3.5Å; T225-F229 PolarHBondContact O-N 2.84Å; F229-Q231 VanDerWaalsContact C-N 3.3Å; F229-Q231 PolarHBondContact O-N 3.4Å; F229-E232 PolarHBondContact O-N 2.97Å; F229-T233 WeakPolarHBondContact O-CB 3.23Å; F229-T233 PolarHBondContact O-N 3.14Å; F229-T233 PolarHBondContact O-OG1 3.21Å; F229-V250 HydrophobicContact CE2-CB 4.4Å; F229-V250 HydrophobicContact CE2-CG1 4.08Å; F229-V250 HydrophobicContact CZ-CB 3.74Å; F229-V250 HydrophobicContact CZ-CG1 3.66Å; F229-V250 HydrophobicContact CZ-CG2 4.28Å; F229-L252 HydrophobicContact CE1-CD2 4.14Å; F229-L252 HydrophobicContact CZ-CD2 4.08Å; F229-L256 HydrophobicContact CB-CD1 4.1Å; F229-L256 HydrophobicContact CD1-CD1 4.22Å; F229-L256 HydrophobicContact CD2-CB 4Å; F229-L256 HydrophobicContact CE2-CB 4Å; F229-L256 HydrophobicContact CG-CB 4.34Å; F229-L256 HydrophobicContact CG-CD1 4.03Å; F229-L256 HydrophobicContact CZ-CB 4.38Å; F229-I258 HydrophobicContact CD2-CD1 3.88Å; F229-I258 HydrophobicContact CD2-CG1 3.6Å; F229-I258 HydrophobicContact CE2-CD1 4.21Å; F229-I258 HydrophobicContact CE2-CG1 3.43Å; F229-I258 VanDerWaalsContact CE2-CG1 3.43Å
230M77.9Confident74.2Confident20 Ų2040 Ų4010%0.09921%0.209CC..Hα-helixtrans-65.3-35.3177.1-75-56.1-60.200111.7L73 L75 A175 L179 A226 Q227 A234L73-M230 HydrophobicContact CB-CE 4.34Å; L73-M230 HydrophobicContact CD1-CE 4.46Å; L75-M230 HydrophobicContact CD1-CG 3.82Å; L75-M230 HydrophobicContact CD1-SD 3.93Å; L75-M230 HydrophobicContact CD2-SD 4.25Å; L75-M230 HydrophobicContact CG-CG 4.05Å; L75-M230 HydrophobicContact CG-SD 3.94Å; A175-M230 HydrophobicContact CB-CE 3.74Å; A175-M230 HydrophobicContact CB-SD 3.79Å; L179-M230 HydrophobicContact CD1-SD 4.42Å; A226-M230 WeakPolarHBondContact O-CB 3.19Å; A226-M230 VanDerWaalsContact O-CG 3.23Å; A226-M230 WeakPolarHBondContact O-CG 3.4Å; A226-M230 PolarHBondContact O-N 2.88Å; Q227-M230 PolarHBondContact O-N 2.55Å; M230-A234 WeakPolarHBondContact O-CB 3.37Å; M230-A234 PolarHBondContact O-N 2.79Å
231Q74.2Confident75Confident98 Ų9841.6 Ų41.646%0.45822%0.216SC..Hα-helixtrans-66.8-51.6174.3-75.5170.9-10.200111.6Q227 A228 F229 T233 A234 V235Q227-Q231 WeakPolarHBondContact O-CB 3.41Å; Q227-Q231 VanDerWaalsContact O-CG 3.26Å; Q227-Q231 WeakPolarHBondContact O-CG 3.38Å; Q227-Q231 PolarHBondContact O-N 3.02Å; A228-Q231 WeakPolarHBondContact O-CB 3.26Å; A228-Q231 PolarHBondContact O-N 2.85Å; F229-Q231 VanDerWaalsContact C-N 3.3Å; F229-Q231 PolarHBondContact O-N 3.4Å; Q231-T233 PolarHBondContact O-N 3.2Å; Q231-A234 PolarHBondContact O-N 3.04Å; Q231-V235 WeakPolarHBondContact O-CG2 3.21Å; Q231-V235 PolarHBondContact O-N 3.11Å
232E78.6Confident76.4Confident13 Ų1342.4 Ų42.46%0.06122%0.219CC..Hα-helixtrans-57.4-50.5177.2-174.2172.8-179.200110.1K218 A228 F229 A234 V235 M236 I258K218-E232 IonicContact NZ-OE1 3.11Å; K218-E232 PolarHBondContact NZ-OE1 3.11Å; K218-E232 IonicContact NZ-OE2 3.39Å; A228-E232 WeakPolarHBondContact O-CB 3.47Å; A228-E232 PolarHBondContact O-N 2.98Å; F229-E232 PolarHBondContact O-N 2.97Å; E232-A234 PolarHBondContact O-N 3.2Å; E232-V235 PolarHBondContact O-N 2.79Å; E232-M236 HydrophobicContact CG-SD 3.99Å; E232-M236 WeakPolarHBondContact O-CB 3.46Å; E232-M236 VanDerWaalsContact O-CG 3.27Å; E232-M236 WeakPolarHBondContact O-CG 3.42Å; E232-M236 PolarHBondContact O-N 2.95Å; E232-I258 HydrophobicContact CB-CD1 4.46Å; E232-I258 HydrophobicContact CG-CD1 4.02Å
233T81.9Confident78.4Confident0 Ų041.3 Ų41.30%021%0.212CC..Hα-helixtrans-59.9-48.5177-54.40000110.7L67 L179 F229 Q231 V235 M236 T237 L247 V250L67-T233 HydrophobicContact CD1-CG2 3.68Å; L179-T233 HydrophobicContact CD2-CG2 4.34Å; F229-T233 WeakPolarHBondContact O-CB 3.23Å; F229-T233 PolarHBondContact O-N 3.14Å; F229-T233 PolarHBondContact O-OG1 3.21Å; Q231-T233 PolarHBondContact O-N 3.2Å; T233-V235 VanDerWaalsContact C-N 3.28Å; T233-V235 PolarHBondContact O-N 2.92Å; T233-M236 PolarHBondContact O-N 2.85Å; T233-M236 VanDerWaalsContact O-N 3.15Å; T233-T237 HydrophobicContact CG2-CG2 4.22Å; T233-T237 VanDerWaalsContact O-CG2 3.29Å; T233-T237 WeakPolarHBondContact O-CG2 3.4Å; T233-T237 PolarHBondContact O-N 2.88Å; T233-T237 PolarHBondContact O-OG1 2.69Å; T233-L247 HydrophobicContact CG2-CD2 4.13Å; T233-V250 HydrophobicContact CG2-CG1 3.62Å
234A83.4Confident80.5Confident5 Ų540.8 Ų40.84%0.04121%0.209CC..Hα-helixtrans-63.3-32.6-178.800000113.3L67 V69 M230 Q231 E232 T237 K238L67-A234 HydrophobicContact CB-CB 4.18Å; V69-A234 HydrophobicContact CG2-CB 3.93Å; M230-A234 WeakPolarHBondContact O-CB 3.37Å; M230-A234 PolarHBondContact O-N 2.79Å; Q231-A234 PolarHBondContact O-N 3.04Å; E232-A234 PolarHBondContact O-N 3.2Å; A234-T237 PolarHBondContact O-OG1 3.35Å; A234-T237 VanDerWaalsContact O-OG1 3.04Å; A234-K238 WeakPolarHBondContact O-CE 3.41Å
235V83.8Confident82.5Confident15 Ų1535.5 Ų35.59%0.09118%0.177CC..Hα-helixtrans-67.6-54.5170.3171.20000109.6Q231 E232 T233 T237 K238 L239 L304 F327 A330Q231-V235 WeakPolarHBondContact O-CG2 3.21Å; Q231-V235 PolarHBondContact O-N 3.11Å; E232-V235 PolarHBondContact O-N 2.79Å; T233-V235 VanDerWaalsContact C-N 3.28Å; T233-V235 PolarHBondContact O-N 2.92Å; V235-T237 VanDerWaalsContact C-N 3.29Å; V235-T237 PolarHBondContact O-N 3Å; V235-K238 WeakPolarHBondContact O-CB 3.43Å; V235-K238 PolarHBondContact O-N 3.03Å; V235-L239 HydrophobicContact CG1-CD1 3.89Å; V235-L239 HydrophobicContact CG1-CG 4.35Å; V235-L239 WeakPolarHBondContact O-CG 3.33Å; V235-L304 HydrophobicContact CG1-CD1 4.28Å; V235-F327 HydrophobicContact CG1-CB 4.33Å; V235-A330 HydrophobicContact CG1-CB 4.14Å
236M87.6Confident84.1Confident10 Ų1037 Ų375%0.04918%0.18CC..Hα-helixtrans-59.3-34.7-175.4-71.3-179.379.100113.6E232 T233 K238 L239 L247 I258 T260 F327E232-M236 HydrophobicContact CG-SD 3.99Å; E232-M236 WeakPolarHBondContact O-CB 3.46Å; E232-M236 VanDerWaalsContact O-CG 3.27Å; E232-M236 WeakPolarHBondContact O-CG 3.42Å; E232-M236 PolarHBondContact O-N 2.95Å; T233-M236 PolarHBondContact O-N 2.85Å; T233-M236 VanDerWaalsContact O-N 3.15Å; M236-K238 PolarHBondContact O-N 3.13Å; M236-K238 VanDerWaalsContact O-N 3.1Å; M236-L239 PolarHBondContact O-N 3.19Å; M236-L247 HydrophobicContact CB-CB 3.97Å; M236-L247 HydrophobicContact CB-CD2 3.85Å; M236-L247 HydrophobicContact CB-CG 4.41Å; M236-L247 HydrophobicContact CE-CB 3.82Å; M236-L247 HydrophobicContact CE-CD1 4.14Å; M236-L247 HydrophobicContact SD-CD1 4.44Å; M236-I258 HydrophobicContact CE-CG2 4.46Å; M236-I258 HydrophobicContact SD-CG2 4.25Å; M236-T260 HydrophobicContact CE-CG2 3.61Å; M236-F327 HydrophobicContact CE-CD2 4.36Å; M236-F327 HydrophobicContact CG-CB 4.3Å; M236-F327 HydrophobicContact CG-CD2 3.69Å; M236-F327 HydrophobicContact CG-CE2 4.49Å; M236-F327 HydrophobicContact CG-CG 4.34Å; M236-F327 HydrophobicContact SD-CD2 4.27Å
237T88.3Confident85.3Confident13 Ų1336.8 Ų36.88%0.0818%0.177CC..THydrogen-bonded Turntrans-62.4-16.2175.660.10000114.3A66 L67 W184 T233 A234 V235 L247A66-T237 WeakPolarHBondContact CB-O 3.4Å; L67-T237 HydrophobicContact CB-CG2 4.33Å; L67-T237 HydrophobicContact CD1-CG2 3.74Å; L67-T237 HydrophobicContact CG-CG2 3.95Å; L67-T237 PolarHBondContact N-OG1 3.28Å; W184-T237 HydrophobicContact CD2-CG2 3.45Å; W184-T237 VanDerWaalsContact CD2-CG2 3.45Å; W184-T237 HydrophobicContact CE3-CG2 3.9Å; W184-T237 HydrophobicContact CG-CG2 3.81Å; W184-T237 HydrophobicContact CH2-CG2 4.19Å; W184-T237 HydrophobicContact CZ2-CG2 3.77Å; W184-T237 HydrophobicContact CZ3-CG2 4.24Å; T233-T237 HydrophobicContact CG2-CG2 4.22Å; T233-T237 VanDerWaalsContact O-CG2 3.29Å; T233-T237 WeakPolarHBondContact O-CG2 3.4Å; T233-T237 PolarHBondContact O-N 2.88Å; T233-T237 PolarHBondContact O-OG1 2.69Å; A234-T237 PolarHBondContact O-OG1 3.35Å; A234-T237 VanDerWaalsContact O-OG1 3.04Å; V235-T237 VanDerWaalsContact C-N 3.29Å; V235-T237 PolarHBondContact O-N 3Å; T237-L247 HydrophobicContact CG2-CD2 3.81Å
238K86Confident86.4Confident71 Ų7130.8 Ų30.831%0.30915%0.15SC..THydrogen-bonded Turntrans-97.9-7.5177.8-60169.1-172.9171.20112.9A66 L67 A234 V235 M236 Y298A66-K238 HydrophobicContact CB-CB 4.43Å; A66-K238 HydrophobicContact CB-CG 3.58Å; L67-K238 VanDerWaalsContact O-CE 3.26Å; L67-K238 WeakPolarHBondContact O-CE 3.16Å; A234-K238 WeakPolarHBondContact O-CE 3.41Å; V235-K238 WeakPolarHBondContact O-CB 3.43Å; V235-K238 PolarHBondContact O-N 3.03Å; M236-K238 PolarHBondContact O-N 3.13Å; M236-K238 VanDerWaalsContact O-N 3.1Å; K238-Y298 PolarHBondContact O-OH 3.22Å
239L88.1Confident87.4Confident18 Ų1829 Ų299%0.09413%0.134CC..  trans-99.9123.3-172.4-60.1-177.2000110.1V235 M236 L244 Y298 L299 L304 F327V235-L239 HydrophobicContact CG1-CD1 3.89Å; V235-L239 HydrophobicContact CG1-CG 4.35Å; V235-L239 WeakPolarHBondContact O-CG 3.33Å; M236-L239 PolarHBondContact O-N 3.19Å; L239-L244 HydrophobicContact CB-CD1 4.23Å; L239-L244 HydrophobicContact CD1-CD1 4.36Å; L239-L244 HydrophobicContact CD2-CD1 4.43Å; L239-Y298 HydrophobicContact CD2-CE1 3.85Å; L239-L299 HydrophobicContact CD1-CD2 3.96Å; L239-L299 HydrophobicContact CD2-CD2 3.57Å; L239-L299 HydrophobicContact CG-CD2 4.41Å; L239-L304 HydrophobicContact CD2-CD1 3.6Å; L239-F327 HydrophobicContact CD1-CD1 3.82Å; L239-F327 HydrophobicContact CD1-CD2 4.14Å; L239-F327 HydrophobicContact CD1-CE1 3.74Å; L239-F327 HydrophobicContact CD1-CE2 4.06Å; L239-F327 HydrophobicContact CD1-CG 4.02Å; L239-F327 HydrophobicContact CD1-CZ 3.87Å
240Q88.5Confident88.1Confident75 Ų7528.9 Ų28.935%0.3513%0.134SC..  trans-145.5103.7174.3-172.2171.713.300108.9G6 Y298G6-Q240 PolarHBondContact O-NE2 3.22Å; G6-Q240 PolarHBondContact O-OE1 2.81Å; Q240-Y298 PolarHBondContact N-OH 3.13Å; Q240-Y298 WeakPolarHBondContact O-CE2 3.48Å
241H92.1Very high88.6Confident52 Ų5228 Ų2824%0.24113%0.13CC..  trans-157.4145.6-179.9-172.3-99000109.4N243 L244 Y298H241-N243 PolarHBondContact CE1-OD1 3.26Å; H241-N243 VanDerWaalsContact CE1-OD1 3.22Å; H241-N243 PolarHBondContact ND1-N 2.9Å; H241-N243 VanDerWaalsContact ND1-N 3.16Å; H241-N243 PolarHBondContact O-N 3.15Å; H241-L244 HydrophobicContact CB-CB 4.28Å; H241-L244 HydrophobicContact CB-CD1 3.95Å; H241-L244 HydrophobicContact CB-CG 3.9Å; H241-L244 PolarHBondContact O-N 3.3Å; H241-L244 VanDerWaalsContact O-N 3.13Å; H241-Y298 HydrophobicContact CB-CD1 3.91Å; H241-Y298 HydrophobicContact CB-CD2 4.17Å; H241-Y298 HydrophobicContact CB-CE1 4.27Å; H241-Y298 HydrophobicContact CB-CG 3.85Å; H241-Y298 AromaticContact CD2-CD2 3.91Å; H241-Y298 AromaticContact CD2-CG 3.95Å; H241-Y298 AromaticContact CG-CG 3.95Å
242K93.6Very high89.1Confident127 Ų12725.5 Ų25.555%0.55212%0.119SC*.THydrogen-bonded Turntrans-61.3-29.4-176.268.3-177.5178.2165.10113.1E294 K323K242-E294 WeakPolarHBondContact CE-OE2 3.47Å; K242-E294 IonicContact NZ-OE1 2.69Å; K242-E294 IonicContact NZ-OE2 3.06Å; K242-E294 PolarHBondContact NZ-OE2 3.16Å; K242-K323 WeakPolarHBondContact O-CD 3.4Å; K242-K323 WeakPolarHBondContact O-CE 3.38Å
243N97.6Very high89.1Confident1 Ų128.3 Ų28.31%0.00513%0.132CC..THydrogen-bonded Turntrans-100.618.7178.6-52.798.8000114.4H241 D291 E294 A322 K323 V324H241-N243 PolarHBondContact CE1-OD1 3.26Å; H241-N243 VanDerWaalsContact CE1-OD1 3.22Å; H241-N243 PolarHBondContact ND1-N 2.9Å; H241-N243 VanDerWaalsContact ND1-N 3.16Å; H241-N243 PolarHBondContact O-N 3.15Å; N243-D291 WeakPolarHBondContact CB-O 3.39Å; N243-D291 WeakPolarHBondContact ND2-CA 3.27Å; N243-D291 VanDerWaalsContact ND2-CB 3.27Å; N243-D291 WeakPolarHBondContact ND2-CB 3.42Å; N243-D291 VanDerWaalsContact ND2-CG 3.32Å; N243-D291 PolarHBondContact ND2-OD1 3.46Å; N243-E294 PolarHBondContact OD1-OE2 2.87Å; N243-E294 VanDerWaalsContact OD1-OE2 3.13Å; N243-A322 PolarHBondContact ND2-O 2.86Å; N243-K323 CarbonylContact O-C 3.55Å; N243-K323 VanDerWaalsContact O-CA 3.26Å; N243-K323 WeakPolarHBondContact O-CA 3.46Å; N243-V324 PolarHBondContact O-N 3.45Å
244L96Very high88.6Confident3 Ų335.2 Ų35.22%0.01616%0.162CC..BIsolated β-bridgetrans-119.6138.5169.8-61.1-176.7000108.6L239 H241 R246 Y298 L299 V324 F327L239-L244 HydrophobicContact CB-CD1 4.23Å; L239-L244 HydrophobicContact CD1-CD1 4.36Å; L239-L244 HydrophobicContact CD2-CD1 4.43Å; H241-L244 HydrophobicContact CB-CB 4.28Å; H241-L244 HydrophobicContact CB-CD1 3.95Å; H241-L244 HydrophobicContact CB-CG 3.9Å; H241-L244 PolarHBondContact O-N 3.3Å; H241-L244 VanDerWaalsContact O-N 3.13Å; L244-R246 PolarHBondContact O-N 3.46Å; L244-Y298 HydrophobicContact CD1-CD1 3.54Å; L244-Y298 HydrophobicContact CD1-CE1 3.96Å; L244-L299 HydrophobicContact CD1-CD2 3.76Å; L244-L299 HydrophobicContact CD1-CG 4.23Å; L244-L299 HydrophobicContact CD2-CD1 4.48Å; L244-L299 HydrophobicContact CD2-CG 4.4Å; L244-V324 HydrophobicContact CD2-CB 3.73Å; L244-V324 HydrophobicContact CD2-CG2 4.25Å; L244-F327 HydrophobicContact CB-CZ 4.18Å; L244-F327 HydrophobicContact CD1-CZ 4.45Å; L244-F327 HydrophobicContact CD2-CE1 4.26Å; L244-F327 HydrophobicContact CD2-CZ 4.01Å; L244-F327 HydrophobicContact CG-CZ 4.44Å
245V94.4Very high88.3Confident8 Ų835.4 Ų35.45%0.04817%0.165CC..PPolyproline II helixtrans-64.7121.4177.1173.30000109.5T260 E261 M263 L315 K323 V324V245-T260 HydrophobicContact CG1-CG2 4.09Å; V245-E261 HydrophobicContact CG1-CG 4.08Å; V245-M263 HydrophobicContact CG2-CG 4.24Å; V245-L315 HydrophobicContact CG2-CB 4.4Å; V245-L315 HydrophobicContact CG2-CD1 4.12Å; V245-K323 HydrophobicContact CG2-CB 3.78Å; V245-V324 PolarHBondContact N-O 3.38Å
246R91.1Very high88.2Confident59 Ų5935.3 Ų35.322%0.22316%0.163CC..PPolyproline II helixtrans-78.9128.8-174.9-176.5169.463.8105.3-10.5111.7N48 L244 L248 T260 E261N48-R246 PolarHBondContact ND2-NH1 2.88Å; L244-R246 PolarHBondContact O-N 3.46Å; R246-L248 VanDerWaalsContact CZ-CD2 3.43Å; R246-T260 VanDerWaalsContact O-CA 3.29Å; R246-T260 WeakPolarHBondContact O-CA 3.33Å; R246-T260 WeakPolarHBondContact O-CB 2.88Å; R246-E261 HydrophobicContact CB-CG 4.29Å; R246-E261 VanDerWaalsContact CB-OE1 3.27Å; R246-E261 WeakPolarHBondContact CB-OE1 3.49Å; R246-E261 PolarHBondContact N-OE1 2.93Å; R246-E261 PolarHBondContact O-N 2.9Å; R246-E261 VanDerWaalsContact O-N 3.09Å
247L92.5Very high88.2Confident4 Ų435.8 Ų35.82%0.02117%0.165CC..EExtended strand (participates in β ladder)trans-70.6127.2164.5-179.169.4000109.9W184 T233 M236 T237 G249 I258W184-L247 HydrophobicContact CE3-CD2 3.68Å; W184-L247 HydrophobicContact CE3-CG 4.07Å; W184-L247 HydrophobicContact CZ3-CB 4.19Å; W184-L247 HydrophobicContact CZ3-CD2 3.67Å; W184-L247 HydrophobicContact CZ3-CG 3.84Å; T233-L247 HydrophobicContact CG2-CD2 4.13Å; M236-L247 HydrophobicContact CB-CB 3.97Å; M236-L247 HydrophobicContact CB-CD2 3.85Å; M236-L247 HydrophobicContact CB-CG 4.41Å; M236-L247 HydrophobicContact CE-CB 3.82Å; M236-L247 HydrophobicContact CE-CD1 4.14Å; M236-L247 HydrophobicContact SD-CD1 4.44Å; T237-L247 HydrophobicContact CG2-CD2 3.81Å; L247-G249 WeakPolarHBondContact CD1-O 3.45Å; L247-I258 HydrophobicContact CD1-CG2 3.55Å
248L90.9Very high88.3Confident15 Ų1535.2 Ų35.28%0.07916%0.162CC..EExtended strand (participates in β ladder)trans-91.5-37171.4-61178.7000110.9R64 V215 R246 V259R64-L248 PolarHBondContact NH1-O 3.49Å; R64-L248 PolarHBondContact NH2-O 2.81Å; V215-L248 HydrophobicContact CB-CD1 4.18Å; V215-L248 HydrophobicContact CG1-CD1 3.31Å; R246-L248 VanDerWaalsContact CZ-CD2 3.43Å; L248-V259 WeakPolarHBondContact CA-O 3.42Å; L248-V259 HydrophobicContact CB-CG1 4.26Å; L248-V259 WeakPolarHBondContact CB-O 3.43Å; L248-V259 HydrophobicContact CD1-CG1 4.37Å; L248-V259 PolarHBondContact N-O 2.96Å
249G91.8Very high88.6Confident0 Ų031.9 Ų31.90%015%0.147CC..EExtended strand (participates in β ladder)trans164.4-165.7175.100000111.6W184 L247 V259W184-G249 CarbonylContact O-C 3.49Å; W184-G249 VanDerWaalsContact O-CA 3.3Å; W184-G249 WeakPolarHBondContact O-CA 3.27Å; L247-G249 WeakPolarHBondContact CD1-O 3.45Å; G249-V259 PolarHBondContact N-O 3.23Å; G249-V259 WeakPolarHBondContact O-CB 3.26Å; G249-V259 PolarHBondContact O-N 3.27Å
250V92.1Very high88.9Confident0 Ų032 Ų320%015%0.149CC..EExtended strand (participates in β ladder)trans-132.4151.4-179.3-620000111.4L179 W184 L186 F229 T233 H257L179-V250 HydrophobicContact CD1-CG2 3.76Å; L179-V250 HydrophobicContact CD2-CG2 3.68Å; L179-V250 HydrophobicContact CG-CG2 4.22Å; W184-V250 PolarHBondContact O-N 3.46Å; L186-V250 PolarHBondContact N-O 2.94Å; F229-V250 HydrophobicContact CE2-CB 4.4Å; F229-V250 HydrophobicContact CE2-CG1 4.08Å; F229-V250 HydrophobicContact CZ-CB 3.74Å; F229-V250 HydrophobicContact CZ-CG1 3.66Å; F229-V250 HydrophobicContact CZ-CG2 4.28Å; T233-V250 HydrophobicContact CG2-CG1 3.62Å; V250-H257 CarbonylContact C-O 3.57Å; V250-H257 WeakPolarHBondContact CA-O 3.42Å; V250-H257 WeakPolarHBondContact CB-O 3.05Å
251I89.3Confident89.1Confident2 Ų229.8 Ų29.81%0.0114%0.139CC..EExtended strand (participates in β ladder)trans-124132.6175.3-59.2164.2000109.4L186 I188 L191 H253 H257 V259L186-I251 HydrophobicContact CB-CD1 4.31Å; L186-I251 HydrophobicContact CB-CG1 3.69Å; I188-I251 HydrophobicContact CB-CG2 3.77Å; I188-I251 HydrophobicContact CD1-CD1 4.23Å; I188-I251 HydrophobicContact CD1-CG2 3.76Å; I188-I251 HydrophobicContact CG1-CG2 4.19Å; L191-I251 HydrophobicContact CB-CD1 4.17Å; L191-I251 HydrophobicContact CD2-CD1 3.6Å; L191-I251 HydrophobicContact CG-CD1 4.4Å; I251-H253 HydrophobicContact CG2-CB 3.96Å; I251-H257 HydrophobicContact CB-CB 4.02Å; I251-H257 PolarHBondContact N-O 3.01Å; I251-H257 PolarHBondContact O-N 3.42Å; I251-H257 PolarHBondContact O-ND1 2.7Å; I251-V259 HydrophobicContact CD1-CG2 3.83Å; I251-V259 HydrophobicContact CG1-CG2 4.16Å
252L83.5Confident89.2Confident44 Ų4428.8 Ų28.823%0.2314%0.135CC..EExtended strand (participates in β ladder)trans-114.572178.9-54.4-179.8000108.8L75 E176 L179 L185 F229 L256L75-L252 HydrophobicContact CD2-CD1 3.54Å; L75-L252 HydrophobicContact CD2-CD2 3.78Å; L75-L252 HydrophobicContact CD2-CG 4.33Å; E176-L252 HydrophobicContact CB-CD1 3.76Å; E176-L252 HydrophobicContact CG-CD1 3.96Å; L179-L252 HydrophobicContact CD1-CD1 3.99Å; L185-L252 HydrophobicContact CD1-CB 4.14Å; L185-L252 HydrophobicContact CD1-CD1 3.83Å; L185-L252 HydrophobicContact CD1-CG 3.68Å; F229-L252 HydrophobicContact CE1-CD2 4.14Å; F229-L252 HydrophobicContact CZ-CD2 4.08Å; L252-L256 HydrophobicContact CD2-CD2 3.39Å
253H77.9Confident89.3Confident72 Ų7223.3 Ų23.333%0.33311%0.112SC..SBendtrans-143.8117.3179.8-176.977.5000110I188 I251 G255 H257I188-H253 HydrophobicContact CB-CB 3.97Å; I188-H253 HydrophobicContact CD1-CB 4.45Å; I188-H253 HydrophobicContact CG1-CB 3.94Å; I188-H253 HydrophobicContact CG2-CB 4.05Å; I251-H253 HydrophobicContact CG2-CB 3.96Å; H253-G255 PolarHBondContact N-O 2.86Å; H253-G255 PolarHBondContact O-N 3.44Å; H253-H257 PolarHBondContact O-CE1 3.06Å
254K72.6Confident89.1Confident146 Ų14627.1 Ų27.164%0.63514%0.135SC*.SBendtrans49.743.7-174.9-60.4179.3-178.9178.90112.5D147D147-K254 VanDerWaalsContact OD1-C 3.28Å; D147-K254 VanDerWaalsContact OD1-CA 3.28Å; D147-K254 WeakPolarHBondContact OD1-CA 3.43Å
255G76.2Confident89.1Confident9 Ų930 Ų309%0.09315%0.148CC..SBendtrans123.7-178.6-174.100000114.7D147 H253 H257D147-G255 PolarHBondContact OD1-N 2.83Å; H253-G255 PolarHBondContact N-O 2.86Å; H253-G255 PolarHBondContact O-N 3.44Å; G255-H257 PolarHBondContact O-CE1 3.37Å; G255-H257 PolarHBondContact O-ND1 3.3Å
256L81.6Confident89Confident12 Ų1231.1 Ų31.16%0.06316%0.16CC..EExtended strand (participates in β ladder)trans-106.9126.8-178.1-55.3-179.8000110.5L75 I146 I220 A226 F229 L252L75-L256 HydrophobicContact CD1-CD1 3.94Å; L75-L256 HydrophobicContact CD1-CD2 3.84Å; I146-L256 HydrophobicContact CD1-CD2 4.11Å; I220-L256 HydrophobicContact CB-CB 4.23Å; I220-L256 PolarHBondContact N-O 3.31Å; A226-L256 HydrophobicContact CB-CD1 4.23Å; F229-L256 HydrophobicContact CB-CD1 4.1Å; F229-L256 HydrophobicContact CD1-CD1 4.22Å; F229-L256 HydrophobicContact CD2-CB 4Å; F229-L256 HydrophobicContact CE2-CB 4Å; F229-L256 HydrophobicContact CG-CB 4.34Å; F229-L256 HydrophobicContact CG-CD1 4.03Å; F229-L256 HydrophobicContact CZ-CB 4.38Å; L252-L256 HydrophobicContact CD2-CD2 3.39Å
257H87.4Confident89.3Confident20 Ų2030.2 Ų30.29%0.09316%0.16CC..EExtended strand (participates in β ladder)trans-129127.4-174.1-5164.6000110V217 K218 T219 V250 I251 H253 G255V217-H257 HydrophobicContact CG1-CB 4.02Å; K218-H257 WeakPolarHBondContact O-CA 3.29Å; T219-H257 WeakPolarHBondContact CG2-CD2 3.34Å; T219-H257 WeakPolarHBondContact CG2-NE2 3.41Å; V250-H257 CarbonylContact C-O 3.57Å; V250-H257 WeakPolarHBondContact CA-O 3.42Å; V250-H257 WeakPolarHBondContact CB-O 3.05Å; I251-H257 HydrophobicContact CB-CB 4.02Å; I251-H257 PolarHBondContact N-O 3.01Å; I251-H257 PolarHBondContact O-N 3.42Å; I251-H257 PolarHBondContact O-ND1 2.7Å; H253-H257 PolarHBondContact O-CE1 3.06Å; G255-H257 PolarHBondContact O-CE1 3.37Å; G255-H257 PolarHBondContact O-ND1 3.3Å
258I90.4Very high89.5Confident2 Ų230 Ų301%0.0116%0.159CC..EExtended strand (participates in β ladder)trans-99.8121.1170-58.2-179.9000107.5K218 I220 F229 E232 M236 L247 T260K218-I258 HydrophobicContact CB-CB 4.37Å; K218-I258 PolarHBondContact N-O 3.1Å; K218-I258 PolarHBondContact O-N 2.97Å; I220-I258 HydrophobicContact CD1-CD1 4.15Å; I220-I258 HydrophobicContact CG1-CD1 4.45Å; I220-I258 HydrophobicContact CG1-CG1 4.48Å; F229-I258 HydrophobicContact CD2-CD1 3.88Å; F229-I258 HydrophobicContact CD2-CG1 3.6Å; F229-I258 HydrophobicContact CE2-CD1 4.21Å; F229-I258 HydrophobicContact CE2-CG1 3.43Å; F229-I258 VanDerWaalsContact CE2-CG1 3.43Å; E232-I258 HydrophobicContact CB-CD1 4.46Å; E232-I258 HydrophobicContact CG-CD1 4.02Å; M236-I258 HydrophobicContact CE-CG2 4.46Å; M236-I258 HydrophobicContact SD-CG2 4.25Å; L247-I258 HydrophobicContact CD1-CG2 3.55Å; I258-T260 HydrophobicContact CG2-CG2 4.17Å
259V93.7Very high89.8Confident0 Ų029.9 Ų29.90%016%0.159CC..EExtended strand (participates in β ladder)trans-106.1118.7-178.8-172.20000109.1L186 V215 A216 V217 L248 G249 I251L186-V259 HydrophobicContact CD1-CB 3.85Å; L186-V259 HydrophobicContact CD1-CG1 4.13Å; L186-V259 HydrophobicContact CD1-CG2 3.94Å; V215-V259 HydrophobicContact CB-CG1 3.75Å; V215-V259 HydrophobicContact CG1-CG1 3.99Å; V215-V259 HydrophobicContact CG2-CG1 3.88Å; A216-V259 WeakPolarHBondContact O-CA 3.42Å; V217-V259 HydrophobicContact CG2-CG2 4.49Å; L248-V259 WeakPolarHBondContact CA-O 3.42Å; L248-V259 HydrophobicContact CB-CG1 4.26Å; L248-V259 WeakPolarHBondContact CB-O 3.43Å; L248-V259 HydrophobicContact CD1-CG1 4.37Å; L248-V259 PolarHBondContact N-O 2.96Å; G249-V259 PolarHBondContact N-O 3.23Å; G249-V259 WeakPolarHBondContact O-CB 3.26Å; G249-V259 PolarHBondContact O-N 3.27Å; I251-V259 HydrophobicContact CD1-CG2 3.83Å; I251-V259 HydrophobicContact CG1-CG2 4.16Å
260T94Very high89.9Confident20 Ų2034 Ų3412%0.12318%0.181CC..EExtended strand (participates in β ladder)trans-122.4169-18057.80000111.5V215 A216 M236 V245 R246 I258V215-T260 WeakPolarHBondContact CA-O 3.28Å; V215-T260 WeakPolarHBondContact CB-O 3.43Å; A216-T260 PolarHBondContact N-O 3.28Å; A216-T260 PolarHBondContact O-N 2.93Å; M236-T260 HydrophobicContact CE-CG2 3.61Å; V245-T260 HydrophobicContact CG1-CG2 4.09Å; R246-T260 VanDerWaalsContact O-CA 3.29Å; R246-T260 WeakPolarHBondContact O-CA 3.33Å; R246-T260 WeakPolarHBondContact O-CB 2.88Å; I258-T260 HydrophobicContact CG2-CG2 4.17Å
261E92.6Very high90.2Very high29 Ų2935 Ų3514%0.13619%0.185CC..EExtended strand (participates in β ladder)trans-55.5144.1165.365-178.6131.500111.2V245 R246 M263 K323V245-E261 HydrophobicContact CG1-CG 4.08Å; R246-E261 HydrophobicContact CB-CG 4.29Å; R246-E261 VanDerWaalsContact CB-OE1 3.27Å; R246-E261 WeakPolarHBondContact CB-OE1 3.49Å; R246-E261 PolarHBondContact N-OE1 2.93Å; R246-E261 PolarHBondContact O-N 2.9Å; R246-E261 VanDerWaalsContact O-N 3.09Å; E261-M263 HydrophobicContact CG-SD 4.2Å; E261-K323 IonicContact OE1-NZ 2.7Å; E261-K323 PolarHBondContact OE1-NZ 3.04Å; E261-K323 IonicContact OE2-NZ 2.78Å; E261-K323 PolarHBondContact OE2-NZ 2.83Å
262L94.5Very high90.5Very high32 Ų3234.9 Ų34.917%0.16818%0.184CC..  trans-82.7128.5176.9-17865000110.5I197 R207 M214 A216 T264I197-L262 HydrophobicContact CD1-CD1 3.88Å; R207-L262 HydrophobicContact CG-CD2 4.13Å; M214-L262 HydrophobicContact CB-CB 4.37Å; M214-L262 HydrophobicContact CB-CD2 3.97Å; M214-L262 HydrophobicContact CE-CD2 3.77Å; A216-L262 HydrophobicContact CB-CD1 4.07Å; L262-T264 HydrophobicContact CD2-CG2 4.27Å; L262-T264 HydrophobicContact CG-CG2 4.36Å
263M95.4Very high91.1Very high12 Ų1239.5 Ų39.56%0.05920%0.199CC..  trans-104.594176.1-58.7-62.7-72.500109V245 E261 K265 G266 L315 I316 K323V245-M263 HydrophobicContact CG2-CG 4.24Å; E261-M263 HydrophobicContact CG-SD 4.2Å; M263-K265 VanDerWaalsContact C-N 3.25Å; M263-K265 PolarHBondContact O-N 3.49Å; M263-G266 PolarHBondContact O-N 3.12Å; M263-G266 VanDerWaalsContact O-N 3.11Å; M263-L315 HydrophobicContact CB-CB 3.58Å; M263-L315 HydrophobicContact CB-CD1 3.99Å; M263-L315 HydrophobicContact CB-CG 4.37Å; M263-L315 HydrophobicContact CE-CB 4.02Å; M263-L315 WeakPolarHBondContact CE-O 3.49Å; M263-L315 HydrophobicContact CG-CB 3.57Å; M263-L315 HydrophobicContact CG-CD1 3.77Å; M263-L315 HydrophobicContact CG-CG 4.33Å; M263-I316 CarbonylContact C-O 3.58Å; M263-I316 VanDerWaalsContact CE-C 3.47Å; M263-K323 HydrophobicContact CE-CB 3.83Å; M263-K323 HydrophobicContact CE-CD 3.7Å; M263-K323 HydrophobicContact CE-CG 3.58Å; M263-K323 HydrophobicContact SD-CD 3.98Å
264T93.4Very high91.9Very high81 Ų8141.3 Ų41.350%0.49722%0.215SC..THydrogen-bonded Turntrans-64.1-24.6-164.955.10000114.5L262 D318L262-T264 HydrophobicContact CD2-CG2 4.27Å; L262-T264 HydrophobicContact CG-CG2 4.36Å; T264-D318 WeakPolarHBondContact OG1-CA 3.23Å; T264-D318 WeakPolarHBondContact OG1-CB 3.36Å; T264-D318 PolarHBondContact OG1-N 3.34Å; T264-D318 PolarHBondContact OG1-OD1 2.71Å; T264-D318 VanDerWaalsContact OG1-OD1 3.12Å
265K95.1Very high93Very high64 Ų6440.3 Ų40.328%0.27821%0.207SC..THydrogen-bonded Turntrans-93.56.1-179.9-68179.2178.5166.70113.4M263 F271 I316 S317 D318 S320M263-K265 VanDerWaalsContact C-N 3.25Å; M263-K265 PolarHBondContact O-N 3.49Å; K265-F271 HydrophobicContact CB-CD2 4Å; K265-F271 HydrophobicContact CB-CE2 4.26Å; K265-F271 HydrophobicContact CD-CD2 4.42Å; K265-F271 HydrophobicContact CD-CE2 3.82Å; K265-F271 HydrophobicContact CG-CE2 4.41Å; K265-I316 HydrophobicContact CB-CB 3.81Å; K265-I316 HydrophobicContact CB-CG2 3.88Å; K265-I316 WeakPolarHBondContact CB-O 3.47Å; K265-I316 HydrophobicContact CD-CG2 4.01Å; K265-I316 PolarHBondContact N-O 3.43Å; K265-I316 VanDerWaalsContact N-O 3.16Å; K265-S317 WeakPolarHBondContact CD-O 3.41Å; K265-D318 VanDerWaalsContact CE-O 3.25Å; K265-D318 WeakPolarHBondContact CE-O 3.39Å; K265-D318 PolarHBondContact NZ-O 3.42Å; K265-S320 PolarHBondContact NZ-OG 2.9Å
266G94Very high93.7Very high31 Ų3140.8 Ų40.832%0.3221%0.212SC..  trans68.9-158.317500000113.5M263 L315 I316M263-G266 PolarHBondContact O-N 3.12Å; M263-G266 VanDerWaalsContact O-N 3.11Å; G266-L315 CarbonylContact O-C 3.49Å; G266-L315 WeakPolarHBondContact O-CA 3.42Å; G266-I316 PolarHBondContact O-N 2.93Å
267N95.4Very high94.1Very high39 Ų3944.6 Ų44.621%0.20923%0.226CC..BIsolated β-bridgetrans-78152.4-179.471.268.8000113V269 N270 F271 R312 V314 L315N267-V269 VanDerWaalsContact C-N 3.31Å; N267-V269 PolarHBondContact O-N 2.74Å; N267-V269 WeakPolarHBondContact OD1-CB 3.17Å; N267-V269 PolarHBondContact OD1-N 3.19Å; N267-N270 PolarHBondContact ND2-ND2 3.5Å; N267-N270 VanDerWaalsContact ND2-ND2 3.19Å; N267-N270 PolarHBondContact O-N 2.97Å; N267-N270 PolarHBondContact OD1-N 3.41Å; N267-F271 WeakPolarHBondContact O-CB 3.42Å; N267-F271 PolarHBondContact O-N 3.19Å; N267-R312 WeakPolarHBondContact CB-O 3.45Å; N267-V314 CarbonylContact C-O 3.51Å; N267-V314 VanDerWaalsContact CA-O 3.24Å; N267-V314 WeakPolarHBondContact CA-O 3.26Å; N267-L315 HydrophobicContact CB-CD2 3.86Å
268L97.6Very high94.1Very high0 Ų049.2 Ų49.20%026%0.26CS..Hα-helixtrans-63.1-33.1-174.3179.858.7000112.7F271 L272 F288 A311 V314 I316 I373L268-F271 PolarHBondContact O-N 2.96Å; L268-L272 HydrophobicContact CD1-CD1 3.8Å; L268-L272 HydrophobicContact CD1-CD2 4.24Å; L268-L272 HydrophobicContact CD1-CG 3.74Å; L268-L272 HydrophobicContact CG-CD1 3.84Å; L268-L272 HydrophobicContact CG-CG 4.24Å; L268-L272 WeakPolarHBondContact O-CB 3.46Å; L268-L272 WeakPolarHBondContact O-CG 3.36Å; L268-L272 PolarHBondContact O-N 2.67Å; L268-F288 HydrophobicContact CD1-CD2 3.75Å; L268-F288 HydrophobicContact CD1-CE2 3.99Å; L268-F288 HydrophobicContact CD1-CG 4.13Å; L268-A311 HydrophobicContact CB-CB 4.47Å; L268-A311 WeakPolarHBondContact CB-O 3.36Å; L268-A311 HydrophobicContact CD2-CB 4.39Å; L268-A311 HydrophobicContact CG-CB 4.47Å; L268-V314 HydrophobicContact CB-CB 3.98Å; L268-V314 HydrophobicContact CB-CG1 4.09Å; L268-V314 HydrophobicContact CD2-CB 4.1Å; L268-V314 HydrophobicContact CD2-CG1 3.89Å; L268-V314 PolarHBondContact N-O 3.11Å; L268-I316 HydrophobicContact CB-CD1 4.12Å; L268-I316 HydrophobicContact CB-CG1 4.37Å; L268-I316 HydrophobicContact CD1-CD1 3.77Å; L268-I316 HydrophobicContact CD1-CG1 4.28Å; L268-I316 HydrophobicContact CG-CD1 4.41Å; L268-I373 HydrophobicContact CD2-CD1 3.9Å; L268-I373 HydrophobicContact CD2-CG1 3.8Å
269V96.6Very high94.2Very high13 Ų1353.6 Ų53.68%0.07929%0.287CS..Hα-helixtrans-60.9-52.8176.2175.40000110.7N267 F271 L272 R273 A311 R312N267-V269 VanDerWaalsContact C-N 3.31Å; N267-V269 PolarHBondContact O-N 2.74Å; N267-V269 WeakPolarHBondContact OD1-CB 3.17Å; N267-V269 PolarHBondContact OD1-N 3.19Å; V269-F271 VanDerWaalsContact C-N 3.34Å; V269-L272 PolarHBondContact O-N 3.32Å; V269-R273 VanDerWaalsContact CG1-CZ 3.45Å; V269-R273 WeakPolarHBondContact O-CB 3.38Å; V269-R273 VanDerWaalsContact O-CG 3.3Å; V269-R273 WeakPolarHBondContact O-CG 3.45Å; V269-R273 PolarHBondContact O-N 3.39Å; V269-A311 HydrophobicContact CG2-CB 3.49Å; V269-A311 VanDerWaalsContact CG2-CB 3.49Å; V269-R312 HydrophobicContact CG2-CB 4.3Å
270N95.3Very high94.3Very high87 Ų8753.8 Ų53.847%0.46529%0.288SS..Hα-helixtrans-66.4-40.1-179.3-72.5-9.9000110.9N267 L272 R273 T274N267-N270 PolarHBondContact ND2-ND2 3.5Å; N267-N270 VanDerWaalsContact ND2-ND2 3.19Å; N267-N270 PolarHBondContact O-N 2.97Å; N267-N270 PolarHBondContact OD1-N 3.41Å; N270-L272 PolarHBondContact O-N 3.02Å; N270-R273 PolarHBondContact O-N 3.39Å; N270-T274 WeakPolarHBondContact O-CB 3.46Å; N270-T274 VanDerWaalsContact O-CG2 3.27Å; N270-T274 WeakPolarHBondContact O-CG2 3.2Å; N270-T274 PolarHBondContact O-N 2.74Å; N270-T274 PolarHBondContact O-OG1 3.47Å
271F96.8Very high94.3Very high19 Ų1954.3 Ų54.38%0.08330%0.297CS..Hα-helixtrans-57.4-50.2175.4-176.5-93.9000111.9K265 N267 L268 V269 T274 R275 V280 F288 I316K265-F271 HydrophobicContact CB-CD2 4Å; K265-F271 HydrophobicContact CB-CE2 4.26Å; K265-F271 HydrophobicContact CD-CD2 4.42Å; K265-F271 HydrophobicContact CD-CE2 3.82Å; K265-F271 HydrophobicContact CG-CE2 4.41Å; N267-F271 WeakPolarHBondContact O-CB 3.42Å; N267-F271 PolarHBondContact O-N 3.19Å; L268-F271 PolarHBondContact O-N 2.96Å; V269-F271 VanDerWaalsContact C-N 3.34Å; F271-T274 PolarHBondContact O-OG1 3.06Å; F271-R275 HydrophobicContact CD2-CG 4.37Å; F271-R275 HydrophobicContact CE1-CG 4.42Å; F271-R275 HydrophobicContact CE2-CG 4.09Å; F271-R275 HydrophobicContact CZ-CG 4.14Å; F271-R275 WeakPolarHBondContact O-CB 3.38Å; F271-R275 VanDerWaalsContact O-CG 3.27Å; F271-R275 WeakPolarHBondContact O-CG 3.47Å; F271-R275 PolarHBondContact O-N 3.43Å; F271-R275 VanDerWaalsContact O-N 3.12Å; F271-V280 HydrophobicContact CE1-CG2 3.86Å; F271-F288 HydrophobicContact CD1-CE2 4.09Å; F271-F288 HydrophobicContact CD1-CZ 4.06Å; F271-F288 AromaticContact CE1-CE2 3.79Å; F271-F288 HydrophobicContact CE1-CE2 3.79Å; F271-F288 AromaticContact CE1-CZ 3.57Å; F271-F288 HydrophobicContact CE1-CZ 3.57Å; F271-F288 HydrophobicContact CZ-CZ 4.32Å; F271-I316 HydrophobicContact CB-CG1 4.28Å; F271-I316 HydrophobicContact CG-CG1 4.26Å
272L97.4Very high94.3Very high0 Ų056.1 Ų56.10%031%0.311CS..Hα-helixtrans-65.2-42.1179.9-70.3170000112.5L268 V269 N270 G276 V280 L285 F288 I373 Y376L268-L272 HydrophobicContact CD1-CD1 3.8Å; L268-L272 HydrophobicContact CD1-CD2 4.24Å; L268-L272 HydrophobicContact CD1-CG 3.74Å; L268-L272 HydrophobicContact CG-CD1 3.84Å; L268-L272 HydrophobicContact CG-CG 4.24Å; L268-L272 WeakPolarHBondContact O-CB 3.46Å; L268-L272 WeakPolarHBondContact O-CG 3.36Å; L268-L272 PolarHBondContact O-N 2.67Å; V269-L272 PolarHBondContact O-N 3.32Å; N270-L272 PolarHBondContact O-N 3.02Å; L272-G276 WeakPolarHBondContact O-CA 3.27Å; L272-G276 PolarHBondContact O-N 2.92Å; L272-V280 HydrophobicContact CD2-CG1 4.12Å; L272-L285 HydrophobicContact CD2-CD2 3.57Å; L272-F288 HydrophobicContact CD2-CE2 4.42Å; L272-I373 HydrophobicContact CD1-CG1 4.45Å; L272-Y376 HydrophobicContact CD2-CD1 4.49Å
273R96.1Very high94.4Very high141 Ų14156.8 Ų56.853%0.53232%0.321SS..Hα-helixtrans-66.2-40.7-179.8-74.6177.2-178.5173.63.5112.8V269 N270 G377V269-R273 VanDerWaalsContact CG1-CZ 3.45Å; V269-R273 WeakPolarHBondContact O-CB 3.38Å; V269-R273 VanDerWaalsContact O-CG 3.3Å; V269-R273 WeakPolarHBondContact O-CG 3.45Å; V269-R273 PolarHBondContact O-N 3.39Å; N270-R273 PolarHBondContact O-N 3.39Å; R273-G377 PolarHBondContact NE-O 2.78Å; R273-G377 PolarHBondContact NH2-O 3.14Å
274T94.7Very high94.4Very high110 Ų11059.1 Ų59.168%0.67533%0.332SS*.Hα-helixtrans-77.9-31.4-176.553.50000112.9N270 F271N270-T274 WeakPolarHBondContact O-CB 3.46Å; N270-T274 VanDerWaalsContact O-CG2 3.27Å; N270-T274 WeakPolarHBondContact O-CG2 3.2Å; N270-T274 PolarHBondContact O-N 2.74Å; N270-T274 PolarHBondContact O-OG1 3.47Å; F271-T274 PolarHBondContact O-OG1 3.06Å
275R94.3Very high94.6Very high126 Ų12655.4 Ų55.448%0.47531%0.309SS..Hα-helixtrans-90.6-36.3-179.5-61.5-62.7-176.8167.1-1.1113F271 V279 V280F271-R275 HydrophobicContact CD2-CG 4.37Å; F271-R275 HydrophobicContact CE1-CG 4.42Å; F271-R275 HydrophobicContact CE2-CG 4.09Å; F271-R275 HydrophobicContact CZ-CG 4.14Å; F271-R275 WeakPolarHBondContact O-CB 3.38Å; F271-R275 VanDerWaalsContact O-CG 3.27Å; F271-R275 WeakPolarHBondContact O-CG 3.47Å; F271-R275 PolarHBondContact O-N 3.43Å; F271-R275 VanDerWaalsContact O-N 3.12Å; R275-V279 HydrophobicContact CB-CB 4.07Å; R275-V279 HydrophobicContact CB-CG1 4.23Å; R275-V279 WeakPolarHBondContact O-CG2 3.5Å; R275-V280 HydrophobicContact CB-CG2 3.73Å
276G90.6Very high94.8Very high18 Ų1852.5 Ų52.519%0.18630%0.297CS..Hα-helixtrans63.4-172.8177.800000114.6L272 S278 V279 V280L272-G276 WeakPolarHBondContact O-CA 3.27Å; L272-G276 PolarHBondContact O-N 2.92Å; G276-S278 VanDerWaalsContact C-N 3.3Å; G276-S278 PolarHBondContact O-N 3.47Å; G276-V279 PolarHBondContact O-N 2.97Å; G276-V280 PolarHBondContact O-N 3.28Å
277R90.9Very high94.9Very high93 Ų9357 Ų5735%0.35130%0.304SS..Hα-helixtrans-65.6-27.5-175.9-73.5171.3-179.478.61.8114.2V279 Y376R277-V279 VanDerWaalsContact C-N 3.3Å; R277-V279 PolarHBondContact O-N 2.91Å; R277-Y376 VanDerWaalsContact CA-CE1 3.47Å; R277-Y376 HydrophobicContact CB-CE1 4.17Å; R277-Y376 HydrophobicContact CG-CD1 4.08Å; R277-Y376 HydrophobicContact CG-CD2 3.75Å; R277-Y376 HydrophobicContact CG-CE1 3.68Å; R277-Y376 HydrophobicContact CG-CE2 3.34Å; R277-Y376 HydrophobicContact CG-CG 4.1Å
278S87.4Confident95.1Very high117 Ų11755.1 Ų55.182%0.81829%0.294SS*.Hα-helixtrans-72.6-24.9-177.950.60000113G276G276-S278 VanDerWaalsContact C-N 3.3Å; G276-S278 PolarHBondContact O-N 3.47Å
279V92.3Very high95.2Very high94 Ų9455.1 Ų55.157%0.5729%0.294SS*.Hα-helixtrans-108.1-37.3-177.7-179.80000111.5R275 G276 R277R275-V279 HydrophobicContact CB-CB 4.07Å; R275-V279 HydrophobicContact CB-CG1 4.23Å; R275-V279 WeakPolarHBondContact O-CG2 3.5Å; G276-V279 PolarHBondContact O-N 2.97Å; R277-V279 VanDerWaalsContact C-N 3.3Å; R277-V279 PolarHBondContact O-N 2.91Å
280V95.1Very high95.3Very high4 Ų454.9 Ų54.92%0.02429%0.292CS..SBendtrans-105.396.8-176.8-173.80000109.4F271 L272 R275 G276 Q284 L285 F288 Y376F271-V280 HydrophobicContact CE1-CG2 3.86Å; L272-V280 HydrophobicContact CD2-CG1 4.12Å; R275-V280 HydrophobicContact CB-CG2 3.73Å; G276-V280 PolarHBondContact O-N 3.28Å; V280-Q284 HydrophobicContact CG1-CB 4.01Å; V280-Q284 HydrophobicContact CG1-CG 3.94Å; V280-L285 HydrophobicContact CG1-CD2 3.59Å; V280-L285 HydrophobicContact CG1-CG 4.17Å; V280-F288 HydrophobicContact CG1-CE2 4.1Å; V280-Y376 HydrophobicContact CB-CE1 4.2Å; V280-Y376 WeakPolarHBondContact O-CE1 3.24Å; V280-Y376 PolarHBondContact O-OH 2.75Å
281G94.7Very high95.4Very high30 Ų3051.3 Ų51.331%0.30927%0.273SS..  trans-78.8171.3178.500000114.3A283 Q284 L285G281-A283 VanDerWaalsContact C-N 3.31Å; G281-A283 PolarHBondContact O-N 3.09Å; G281-Q284 PolarHBondContact O-N 3.06Å; G281-L285 PolarHBondContact O-N 3.26Å
282P93.4Very high95.5Very high67 Ų6750.4 Ų50.444%0.43527%0.269SS..Hα-helixtrans-55.9-37.5-177-27.535.4000115Q284 L285 L286P282-Q284 VanDerWaalsContact C-N 3.32Å; P282-Q284 PolarHBondContact O-N 3.43Å; P282-L285 WeakPolarHBondContact O-CB 3.46Å; P282-L285 PolarHBondContact O-N 3.31Å; P282-L286 PolarHBondContact O-N 3.19Å
283A94.9Very high95.6Very high46 Ų4650.4 Ų50.438%0.3827%0.269SS..Hα-helixtrans-62.2-39.4177.600000112.1G281 L286 R287 L438G281-A283 VanDerWaalsContact C-N 3.31Å; G281-A283 PolarHBondContact O-N 3.09Å; A283-L286 PolarHBondContact O-N 3.41Å; A283-R287 PolarHBondContact O-N 3.33Å; A283-L438 HydrophobicContact CB-CD1 4.49Å
284Q96.6Very high95.7Very high62 Ų6245.2 Ų45.229%0.2925%0.251SS..Hα-helixtrans-71.4-36.2177.1-173.761.251.500111.7V280 G281 P282 R287 F288V280-Q284 HydrophobicContact CG1-CB 4.01Å; V280-Q284 HydrophobicContact CG1-CG 3.94Å; G281-Q284 PolarHBondContact O-N 3.06Å; P282-Q284 VanDerWaalsContact C-N 3.32Å; P282-Q284 PolarHBondContact O-N 3.43Å; Q284-R287 PolarHBondContact O-N 3.05Å; Q284-F288 HydrophobicContact CG-CD2 4.27Å; Q284-F288 HydrophobicContact CG-CE1 4.35Å; Q284-F288 HydrophobicContact CG-CE2 3.72Å; Q284-F288 HydrophobicContact CG-CZ 3.77Å; Q284-F288 VanDerWaalsContact NE2-CZ 3.34Å; Q284-F288 WeakPolarHBondContact O-CD2 3.41Å; Q284-F288 WeakPolarHBondContact O-CG 3.34Å; Q284-F288 PolarHBondContact O-N 3.23Å
285L97.9Very high95.9Very high3 Ų340 Ų402%0.01622%0.219CC..Hα-helixtrans-61.6-43.2172.9-62.5-177.9000111.8L272 V280 G281 P282 R287 F288 S289 I373 F374 Y376L272-L285 HydrophobicContact CD2-CD2 3.57Å; V280-L285 HydrophobicContact CG1-CD2 3.59Å; V280-L285 HydrophobicContact CG1-CG 4.17Å; G281-L285 PolarHBondContact O-N 3.26Å; P282-L285 WeakPolarHBondContact O-CB 3.46Å; P282-L285 PolarHBondContact O-N 3.31Å; L285-R287 VanDerWaalsContact C-N 3.35Å; L285-F288 PolarHBondContact O-N 3.5Å; L285-S289 WeakPolarHBondContact O-CB 3.43Å; L285-S289 PolarHBondContact O-N 2.73Å; L285-S289 PolarHBondContact O-OG 2.87Å; L285-I373 HydrophobicContact CB-CG2 3.77Å; L285-I373 HydrophobicContact CD2-CG2 3.74Å; L285-I373 HydrophobicContact CG-CG2 4.26Å; L285-F374 HydrophobicContact CB-CE1 4.1Å; L285-F374 HydrophobicContact CB-CZ 4.23Å; L285-F374 HydrophobicContact CD1-CD1 3.93Å; L285-F374 HydrophobicContact CD1-CE1 4.21Å; L285-Y376 HydrophobicContact CD1-CE1 4.41Å; L285-Y376 HydrophobicContact CD1-CE2 3.96Å; L285-Y376 HydrophobicContact CD2-CE1 4.33Å
286L97.8Very high96Very high3 Ų334 Ų342%0.01620%0.196CC..Hα-helixtrans-64.6-38.3173.5-75.7168.7000111.6P282 A283 S289 L290 F374 L434 E437 L438 T441P282-L286 PolarHBondContact O-N 3.19Å; A283-L286 PolarHBondContact O-N 3.41Å; L286-S289 WeakPolarHBondContact O-CB 3.49Å; L286-S289 PolarHBondContact O-N 2.93Å; L286-L290 WeakPolarHBondContact O-CB 3.32Å; L286-L290 PolarHBondContact O-N 2.9Å; L286-F374 HydrophobicContact CD2-CZ 3.82Å; L286-F374 HydrophobicContact CG-CZ 4.06Å; L286-L434 HydrophobicContact CD2-CD2 4.2Å; L286-E437 HydrophobicContact CD1-CB 4.28Å; L286-E437 HydrophobicContact CD2-CB 3.97Å; L286-L438 HydrophobicContact CB-CD1 3.77Å; L286-L438 HydrophobicContact CD1-CD1 4.45Å; L286-T441 HydrophobicContact CD1-CG2 3.77Å
287R98.1Very high96.4Very high124 Ų12435.2 Ų35.247%0.46820%0.197SC..Hα-helixtrans-62.6-47174.3-176.569.199.6-1675.9111.9A283 Q284 L285 S289 L290 D291A283-R287 PolarHBondContact O-N 3.33Å; Q284-R287 PolarHBondContact O-N 3.05Å; L285-R287 VanDerWaalsContact C-N 3.35Å; R287-S289 VanDerWaalsContact C-N 3.27Å; R287-S289 PolarHBondContact O-N 2.86Å; R287-L290 PolarHBondContact O-N 2.8Å; R287-D291 WeakPolarHBondContact O-CB 3.21Å; R287-D291 PolarHBondContact O-N 3.26Å
288F98.6Very high96.7Very high0 Ų032.8 Ų32.80%019%0.188CC..Hα-helixtrans-60.1-39.4174.7-66.7-36.1000112.3L268 F271 L272 V280 Q284 L285 V292 I316 S320 A322 I373L268-F288 HydrophobicContact CD1-CD2 3.75Å; L268-F288 HydrophobicContact CD1-CE2 3.99Å; L268-F288 HydrophobicContact CD1-CG 4.13Å; F271-F288 HydrophobicContact CD1-CE2 4.09Å; F271-F288 HydrophobicContact CD1-CZ 4.06Å; F271-F288 AromaticContact CE1-CE2 3.79Å; F271-F288 HydrophobicContact CE1-CE2 3.79Å; F271-F288 AromaticContact CE1-CZ 3.57Å; F271-F288 HydrophobicContact CE1-CZ 3.57Å; F271-F288 HydrophobicContact CZ-CZ 4.32Å; L272-F288 HydrophobicContact CD2-CE2 4.42Å; V280-F288 HydrophobicContact CG1-CE2 4.1Å; Q284-F288 HydrophobicContact CG-CD2 4.27Å; Q284-F288 HydrophobicContact CG-CE1 4.35Å; Q284-F288 HydrophobicContact CG-CE2 3.72Å; Q284-F288 HydrophobicContact CG-CZ 3.77Å; Q284-F288 VanDerWaalsContact NE2-CZ 3.34Å; Q284-F288 WeakPolarHBondContact O-CD2 3.41Å; Q284-F288 WeakPolarHBondContact O-CG 3.34Å; Q284-F288 PolarHBondContact O-N 3.23Å; L285-F288 PolarHBondContact O-N 3.5Å; F288-V292 WeakPolarHBondContact O-CG2 2.83Å; F288-V292 PolarHBondContact O-N 3.38Å; F288-V292 VanDerWaalsContact O-N 3.12Å; F288-I316 HydrophobicContact CD1-CD1 4.2Å; F288-I316 HydrophobicContact CE1-CD1 3.97Å; F288-I316 HydrophobicContact CE1-CG2 4.33Å; F288-I316 HydrophobicContact CZ-CD1 4.43Å; F288-S320 WeakPolarHBondContact CE1-O 3.41Å; F288-A322 HydrophobicContact CB-CB 4.36Å; F288-A322 HydrophobicContact CD1-CB 3.87Å; F288-A322 HydrophobicContact CG-CB 4.49Å; F288-I373 HydrophobicContact CB-CD1 4.28Å
289S98.7Very high97.1Very high0 Ų027.4 Ų27.40%015%0.15CC..Hα-helixtrans-60.8-48.2175.1-58.10000110.9L285 L286 R287 V292 C293 Y366 L370L285-S289 WeakPolarHBondContact O-CB 3.43Å; L285-S289 PolarHBondContact O-N 2.73Å; L285-S289 PolarHBondContact O-OG 2.87Å; L286-S289 WeakPolarHBondContact O-CB 3.49Å; L286-S289 PolarHBondContact O-N 2.93Å; R287-S289 VanDerWaalsContact C-N 3.27Å; R287-S289 PolarHBondContact O-N 2.86Å; S289-V292 PolarHBondContact O-N 3.19Å; S289-C293 WeakPolarHBondContact O-CB 3.15Å; S289-C293 PolarHBondContact O-N 3.12Å; S289-Y366 PolarHBondContact O-OH 3.15Å; S289-L370 VanDerWaalsContact CB-CD2 3.45Å; S289-L370 VanDerWaalsContact OG-CD2 3.23Å; S289-L370 WeakPolarHBondContact OG-CD2 3.46Å
290L98.6Very high97.2Very high8 Ų825.1 Ų25.14%0.04213%0.134CC..Hα-helixtrans-62-47.3179.4-175.364000111.9L286 R287 V292 C293 E294 R431 L434 E435 L438L286-L290 WeakPolarHBondContact O-CB 3.32Å; L286-L290 PolarHBondContact O-N 2.9Å; R287-L290 PolarHBondContact O-N 2.8Å; L290-V292 VanDerWaalsContact C-N 3.35Å; L290-V292 PolarHBondContact O-N 2.88Å; L290-C293 WeakPolarHBondContact O-CA 3.33Å; L290-C293 WeakPolarHBondContact O-CB 3.49Å; L290-C293 PolarHBondContact O-N 3.46Å; L290-C293 VanDerWaalsContact O-N 3.09Å; L290-E294 WeakPolarHBondContact O-CG 3.24Å; L290-E294 PolarHBondContact O-N 2.91Å; L290-R431 HydrophobicContact CD1-CG 3.65Å; L290-L434 HydrophobicContact CD1-CB 4.07Å; L290-E435 HydrophobicContact CD1-CG 3.8Å; L290-E435 HydrophobicContact CD2-CG 4.19Å; L290-L438 HydrophobicContact CD2-CD2 4.11Å
291D98.8Very high97.2Very high13 Ų1328.8 Ų28.87%0.0716%0.159CC..Hα-helixtrans-54.2-49.8176.6-80.6-14.9000111.6N243 R287 C293 E294 G295 A322N243-D291 WeakPolarHBondContact CB-O 3.39Å; N243-D291 WeakPolarHBondContact ND2-CA 3.27Å; N243-D291 VanDerWaalsContact ND2-CB 3.27Å; N243-D291 WeakPolarHBondContact ND2-CB 3.42Å; N243-D291 VanDerWaalsContact ND2-CG 3.32Å; N243-D291 PolarHBondContact ND2-OD1 3.46Å; R287-D291 WeakPolarHBondContact O-CB 3.21Å; R287-D291 PolarHBondContact O-N 3.26Å; D291-C293 VanDerWaalsContact C-N 3.33Å; D291-C293 PolarHBondContact O-N 3.44Å; D291-E294 PolarHBondContact O-N 3.44Å; D291-G295 PolarHBondContact O-N 3.37Å; D291-G295 VanDerWaalsContact O-N 3.13Å; D291-A322 HydrophobicContact CB-CB 3.79Å; D291-A322 PolarHBondContact OD2-N 2.98Å
292V98.8Very high97Very high0 Ų032.1 Ų32.10%017%0.165CC..Hα-helixtrans-63.6-41.1177.1173.50000110.8F288 S289 L290 E294 G295 M296 L309 V314 A322 V324 Y366 L369F288-V292 WeakPolarHBondContact O-CG2 2.83Å; F288-V292 PolarHBondContact O-N 3.38Å; F288-V292 VanDerWaalsContact O-N 3.12Å; S289-V292 PolarHBondContact O-N 3.19Å; L290-V292 VanDerWaalsContact C-N 3.35Å; L290-V292 PolarHBondContact O-N 2.88Å; V292-E294 PolarHBondContact O-N 3.48Å; V292-G295 PolarHBondContact O-N 3.28Å; V292-M296 HydrophobicContact CG1-CG 4.34Å; V292-M296 WeakPolarHBondContact O-CG 3.46Å; V292-M296 PolarHBondContact O-N 3.1Å; V292-L309 HydrophobicContact CG1-CD1 4.17Å; V292-V314 HydrophobicContact CG2-CB 4.47Å; V292-V314 HydrophobicContact CG2-CG1 3.76Å; V292-V314 HydrophobicContact CG2-CG2 3.82Å; V292-A322 HydrophobicContact CG2-CB 4.22Å; V292-V324 HydrophobicContact CB-CG2 4.42Å; V292-V324 HydrophobicContact CG1-CG2 3.95Å; V292-V324 HydrophobicContact CG2-CG2 4.44Å; V292-Y366 HydrophobicContact CB-CE2 4.21Å; V292-Y366 HydrophobicContact CG1-CD2 3.95Å; V292-Y366 HydrophobicContact CG1-CE2 3.81Å; V292-L369 HydrophobicContact CG1-CD1 3.91Å; V292-L369 HydrophobicContact CG1-CD2 4.19Å
293C98.8Very high96.9Very high0 Ų036.1 Ų36.10%018%0.176CC..Hα-helixtrans-60.9-43.5178.3-1640000112.4S289 L290 D291 M296 E297 Y366 F427 R431 L434S289-C293 WeakPolarHBondContact O-CB 3.15Å; S289-C293 PolarHBondContact O-N 3.12Å; L290-C293 WeakPolarHBondContact O-CA 3.33Å; L290-C293 WeakPolarHBondContact O-CB 3.49Å; L290-C293 PolarHBondContact O-N 3.46Å; L290-C293 VanDerWaalsContact O-N 3.09Å; D291-C293 VanDerWaalsContact C-N 3.33Å; D291-C293 PolarHBondContact O-N 3.44Å; C293-M296 PolarHBondContact O-N 2.95Å; C293-E297 WeakPolarHBondContact O-CB 3.03Å; C293-E297 PolarHBondContact O-N 3.07Å; C293-Y366 HydrophobicContact CB-CE2 4.33Å; C293-Y366 WeakPolarHBondContact CB-OH 3.5Å; C293-F427 PolarHBondContact SG-O 2.88Å; C293-F427 VanDerWaalsContact SG-O 3.4Å; C293-R431 PolarHBondContact SG-N 3.1Å; C293-R431 VanDerWaalsContact SG-N 3.4Å; C293-L434 HydrophobicContact CB-CD1 3.85Å
294E98.6Very high96.7Very high31 Ų3134.3 Ų34.315%0.14516%0.16CC..Hα-helixtrans-63.4-42.1176.7-71.3-179171.100111.2K242 N243 L290 D291 V292 M296 E297 Y298 R431K242-E294 WeakPolarHBondContact CE-OE2 3.47Å; K242-E294 IonicContact NZ-OE1 2.69Å; K242-E294 IonicContact NZ-OE2 3.06Å; K242-E294 PolarHBondContact NZ-OE2 3.16Å; N243-E294 PolarHBondContact OD1-OE2 2.87Å; N243-E294 VanDerWaalsContact OD1-OE2 3.13Å; L290-E294 WeakPolarHBondContact O-CG 3.24Å; L290-E294 PolarHBondContact O-N 2.91Å; D291-E294 PolarHBondContact O-N 3.44Å; V292-E294 PolarHBondContact O-N 3.48Å; E294-M296 VanDerWaalsContact C-N 3.35Å; E294-M296 PolarHBondContact O-N 3.01Å; E294-E297 PolarHBondContact O-N 2.84Å; E294-Y298 PolarHBondContact O-N 3.26Å; E294-Y298 VanDerWaalsContact O-N 3.08Å; E294-R431 HydrophobicContact CG-CG 4.31Å
295G98.1Very high96.4Very high0 Ų031.4 Ų31.40%015%0.146CC..Hα-helixtrans-59.7-43.4173.300000112.8D291 V292 Y298 L299D291-G295 PolarHBondContact O-N 3.37Å; D291-G295 VanDerWaalsContact O-N 3.13Å; V292-G295 PolarHBondContact O-N 3.28Å; G295-Y298 WeakPolarHBondContact O-CB 3.44Å; G295-Y298 PolarHBondContact O-N 3.34Å; G295-L299 PolarHBondContact O-N 3.23Å; G295-L299 VanDerWaalsContact O-N 3.16Å
296M98.4Very high96.2Very high1 Ų131.2 Ų31.21%0.00515%0.145CC..Hα-helixtrans-74.4-32.4179.5-66.8-56.6-56.400113.3V292 C293 E294 Y298 L299 E300 H306 L309 V324 D362 F427V292-M296 HydrophobicContact CG1-CG 4.34Å; V292-M296 WeakPolarHBondContact O-CG 3.46Å; V292-M296 PolarHBondContact O-N 3.1Å; C293-M296 PolarHBondContact O-N 2.95Å; E294-M296 VanDerWaalsContact C-N 3.35Å; E294-M296 PolarHBondContact O-N 3.01Å; M296-Y298 VanDerWaalsContact C-N 3.3Å; M296-Y298 PolarHBondContact O-N 2.86Å; M296-L299 HydrophobicContact CE-CD1 4.09Å; M296-L299 PolarHBondContact O-N 3.4Å; M296-L299 HydrophobicContact SD-CD1 3.76Å; M296-E300 WeakPolarHBondContact O-CB 3.43Å; M296-E300 PolarHBondContact O-N 2.76Å; M296-H306 HydrophobicContact CE-CB 3.97Å; M296-H306 HydrophobicContact SD-CB 4.45Å; M296-L309 HydrophobicContact CE-CD2 4.04Å; M296-L309 HydrophobicContact CG-CD1 4.37Å; M296-L309 HydrophobicContact CG-CD2 3.85Å; M296-L309 HydrophobicContact SD-CD1 3.92Å; M296-L309 HydrophobicContact SD-CD2 3.89Å; M296-L309 HydrophobicContact SD-CG 4.43Å; M296-V324 HydrophobicContact SD-CG1 4.34Å; M296-V324 HydrophobicContact SD-CG2 4.48Å; M296-D362 HydrophobicContact CE-CB 3.81Å; M296-F427 HydrophobicContact CB-CD1 3.49Å; M296-F427 VanDerWaalsContact CB-CD1 3.49Å; M296-F427 HydrophobicContact CB-CD2 3.97Å; M296-F427 HydrophobicContact CB-CE1 3.35Å; M296-F427 HydrophobicContact CB-CE2 3.83Å; M296-F427 HydrophobicContact CB-CG 3.81Å; M296-F427 HydrophobicContact CB-CZ 3.53Å; M296-F427 HydrophobicContact CE-CE2 4.09Å; M296-F427 HydrophobicContact CE-CZ 3.93Å; M296-F427 HydrophobicContact CG-CD1 4.47Å; M296-F427 HydrophobicContact CG-CE1 3.9Å; M296-F427 HydrophobicContact CG-CZ 4Å
297E98.3Very high95.9Very high44 Ų4432 Ų3221%0.20615%0.148CC..Hα-helixtrans-59.9-42.5169.6-176.2177.7-164.100110.8C293 E294 E300 S301 F427 S428 R431C293-E297 WeakPolarHBondContact O-CB 3.03Å; C293-E297 PolarHBondContact O-N 3.07Å; E294-E297 PolarHBondContact O-N 2.84Å; E297-E300 PolarHBondContact O-N 3.09Å; E297-S301 PolarHBondContact O-N 2.96Å; E297-F427 HydrophobicContact CB-CB 3.81Å; E297-F427 HydrophobicContact CG-CB 4.46Å; E297-S428 VanDerWaalsContact OE1-CA 3.28Å; E297-S428 WeakPolarHBondContact OE1-CA 3.33Å; E297-S428 WeakPolarHBondContact OE1-CB 3.49Å; E297-S428 PolarHBondContact OE1-OG 2.88Å; E297-R431 IonicContact OE1-NE 2.67Å; E297-R431 IonicContact OE1-NH2 3.92Å; E297-R431 WeakPolarHBondContact OE2-CD 2.91Å; E297-R431 IonicContact OE2-CZ 3.5Å; E297-R431 IonicContact OE2-NE 3.12Å; E297-R431 PolarHBondContact OE2-NE 3.03Å
298Y96.7Very high95.5Very high42 Ų4226.9 Ų26.917%0.16513%0.13CC..Hα-helixtrans-60.7-45.9173.8177.4-93.3000111.7K238 L239 Q240 H241 L244 E294 G295 M296 E300 S301 K302K238-Y298 PolarHBondContact O-OH 3.22Å; L239-Y298 HydrophobicContact CD2-CE1 3.85Å; Q240-Y298 PolarHBondContact N-OH 3.13Å; Q240-Y298 WeakPolarHBondContact O-CE2 3.48Å; H241-Y298 HydrophobicContact CB-CD1 3.91Å; H241-Y298 HydrophobicContact CB-CD2 4.17Å; H241-Y298 HydrophobicContact CB-CE1 4.27Å; H241-Y298 HydrophobicContact CB-CG 3.85Å; H241-Y298 AromaticContact CD2-CD2 3.91Å; H241-Y298 AromaticContact CD2-CG 3.95Å; H241-Y298 AromaticContact CG-CG 3.95Å; L244-Y298 HydrophobicContact CD1-CD1 3.54Å; L244-Y298 HydrophobicContact CD1-CE1 3.96Å; E294-Y298 PolarHBondContact O-N 3.26Å; E294-Y298 VanDerWaalsContact O-N 3.08Å; G295-Y298 WeakPolarHBondContact O-CB 3.44Å; G295-Y298 PolarHBondContact O-N 3.34Å; M296-Y298 VanDerWaalsContact C-N 3.3Å; M296-Y298 PolarHBondContact O-N 2.86Å; Y298-E300 PolarHBondContact O-N 3.29Å; Y298-S301 WeakPolarHBondContact O-CB 3.25Å; Y298-S301 PolarHBondContact O-N 3.4Å; Y298-S301 PolarHBondContact O-OG 3.39Å; Y298-K302 HydrophobicContact CD1-CG 4.44Å; Y298-K302 HydrophobicContact CE1-CG 4.02Å; Y298-K302 VanDerWaalsContact CZ-CE 3.44Å; Y298-K302 WeakPolarHBondContact O-CG 3.48Å; Y298-K302 PolarHBondContact O-N 3.08Å; Y298-K302 WeakPolarHBondContact OH-CE 3.46Å
299L94.9Very high95.4Very high3 Ų326.9 Ų26.92%0.01613%0.13CC..Hα-helixtrans-61.7-41.7176.6-65.4-177000112.5L239 L244 G295 M296 S301 K302 K303 L304 H306 F327L239-L299 HydrophobicContact CD1-CD2 3.96Å; L239-L299 HydrophobicContact CD2-CD2 3.57Å; L239-L299 HydrophobicContact CG-CD2 4.41Å; L244-L299 HydrophobicContact CD1-CD2 3.76Å; L244-L299 HydrophobicContact CD1-CG 4.23Å; L244-L299 HydrophobicContact CD2-CD1 4.48Å; L244-L299 HydrophobicContact CD2-CG 4.4Å; G295-L299 PolarHBondContact O-N 3.23Å; G295-L299 VanDerWaalsContact O-N 3.16Å; M296-L299 HydrophobicContact CE-CD1 4.09Å; M296-L299 PolarHBondContact O-N 3.4Å; M296-L299 HydrophobicContact SD-CD1 3.76Å; L299-S301 VanDerWaalsContact C-N 3.32Å; L299-S301 PolarHBondContact O-N 3.4Å; L299-K302 CarbonylContact O-C 3.49Å; L299-K302 WeakPolarHBondContact O-CA 3.46Å; L299-K302 PolarHBondContact O-N 3.47Å; L299-K303 PolarHBondContact O-N 3.13Å; L299-K303 VanDerWaalsContact O-N 3.12Å; L299-L304 HydrophobicContact CD2-CB 4.45Å; L299-L304 PolarHBondContact O-N 2.88Å; L299-H306 HydrophobicContact CD1-CB 4.27Å; L299-F327 HydrophobicContact CD1-CE1 4.06Å; L299-F327 HydrophobicContact CD2-CE1 4.34Å
300E95.4Very high95.3Very high47 Ų4726.9 Ų26.922%0.2213%0.13CC..Hα-helixtrans-58.4-43.4174.6176.4164.6-116.600111M296 E297 Y298 K302 K303 T359 F427M296-E300 WeakPolarHBondContact O-CB 3.43Å; M296-E300 PolarHBondContact O-N 2.76Å; E297-E300 PolarHBondContact O-N 3.09Å; Y298-E300 PolarHBondContact O-N 3.29Å; E300-K302 PolarHBondContact O-N 3.5Å; E300-K303 PolarHBondContact O-N 2.89Å; E300-T359 HydrophobicContact CB-CG2 4.34Å; E300-T359 HydrophobicContact CG-CG2 4.13Å; E300-T359 PolarHBondContact OE1-OG1 3.1Å; E300-T359 VanDerWaalsContact OE1-OG1 3.1Å; E300-F427 HydrophobicContact CB-CD2 4.24Å; E300-F427 PolarHBondContact OE2-N 3.36Å
301S95Very high95.3Very high81 Ų8126.5 Ų26.557%0.56613%0.128SC*.Hα-helixtrans-62.1-28.517684.70000113.3E297 Y298 L299E297-S301 PolarHBondContact O-N 2.96Å; Y298-S301 WeakPolarHBondContact O-CB 3.25Å; Y298-S301 PolarHBondContact O-N 3.4Å; Y298-S301 PolarHBondContact O-OG 3.39Å; L299-S301 VanDerWaalsContact C-N 3.32Å; L299-S301 PolarHBondContact O-N 3.4Å
302K90.6Very high95.1Very high99 Ų9929.9 Ų29.943%0.4314%0.14SC..THydrogen-bonded Turntrans-89.31.4176.1-61.2-58.8-176.4-1790113.3Y298 L299 E300 L304Y298-K302 HydrophobicContact CD1-CG 4.44Å; Y298-K302 HydrophobicContact CE1-CG 4.02Å; Y298-K302 VanDerWaalsContact CZ-CE 3.44Å; Y298-K302 WeakPolarHBondContact O-CG 3.48Å; Y298-K302 PolarHBondContact O-N 3.08Å; Y298-K302 WeakPolarHBondContact OH-CE 3.46Å; L299-K302 CarbonylContact O-C 3.49Å; L299-K302 WeakPolarHBondContact O-CA 3.46Å; L299-K302 PolarHBondContact O-N 3.47Å; E300-K302 PolarHBondContact O-N 3.5Å; K302-L304 HydrophobicContact CB-CD1 3.95Å; K302-L304 HydrophobicContact CB-CG 4.17Å; K302-L304 PolarHBondContact O-N 3.16Å
303K90.9Very high95Very high151 Ų15130.5 Ų30.566%0.65714%0.143SC*.THydrogen-bonded Turntrans56.133.5-175.1-53.9179.8-179.3178.80112.8L299 E300 D333L299-K303 PolarHBondContact O-N 3.13Å; L299-K303 VanDerWaalsContact O-N 3.12Å; E300-K303 PolarHBondContact O-N 2.89Å; K303-D333 PolarHBondContact O-N 3.4Å
304L90.6Very high94.9Very high8 Ų830.5 Ų30.54%0.04214%0.143CC..EExtended strand (participates in β ladder)trans-102.7129.9177.2-72.3170.3000109.4V235 L239 L299 K302 M332V235-L304 HydrophobicContact CG1-CD1 4.28Å; L239-L304 HydrophobicContact CD2-CD1 3.6Å; L299-L304 HydrophobicContact CD2-CB 4.45Å; L299-L304 PolarHBondContact O-N 2.88Å; K302-L304 HydrophobicContact CB-CD1 3.95Å; K302-L304 HydrophobicContact CB-CG 4.17Å; K302-L304 PolarHBondContact O-N 3.16Å; L304-M332 HydrophobicContact CD2-CE 3.92Å; L304-M332 HydrophobicContact CD2-CG 4.15Å; L304-M332 HydrophobicContact CD2-SD 3.64Å; L304-M332 HydrophobicContact CG-CE 4.48Å; L304-M332 HydrophobicContact CG-SD 4.22Å
305V91.8Very high94.9Very high1 Ų131.1 Ų31.11%0.00615%0.147CC..EExtended strand (participates in β ladder)trans-102.6125.4176.4-171.90000107.7R307 A330 K331 D333 F357 S358 D362V305-R307 HydrophobicContact CB-CG 4.3Å; V305-R307 HydrophobicContact CG1-CG 3.76Å; V305-A330 WeakPolarHBondContact O-CA 3.3Å; V305-K331 PolarHBondContact N-O 3.43Å; V305-K331 PolarHBondContact O-N 3.25Å; V305-D333 HydrophobicContact CG2-CB 3.88Å; V305-F357 HydrophobicContact CG1-CB 4.23Å; V305-S358 WeakPolarHBondContact CG1-O 3.28Å; V305-D362 WeakPolarHBondContact CA-OD2 3.33Å; V305-D362 VanDerWaalsContact CG1-OD2 3.3Å; V305-D362 WeakPolarHBondContact CG1-OD2 3.44Å
306H92.4Very high94.9Very high0 Ų031.1 Ų31.10%015%0.147CC..  trans-75.1-41-177.5-172.1-43.3000112.5M296 L299 D308 V324 S325 D326 D362M296-H306 HydrophobicContact CE-CB 3.97Å; M296-H306 HydrophobicContact SD-CB 4.45Å; L299-H306 HydrophobicContact CD1-CB 4.27Å; H306-D308 PolarHBondContact CE1-O 3.4Å; H306-D308 PolarHBondContact ND1-N 3.39Å; H306-D308 PolarHBondContact O-N 3.22Å; H306-V324 WeakPolarHBondContact CD2-CG1 3.48Å; H306-V324 WeakPolarHBondContact NE2-CG1 2.98Å; H306-S325 PolarHBondContact CE1-O 3.22Å; H306-S325 PolarHBondContact NE2-O 3.35Å; H306-S325 VanDerWaalsContact NE2-O 3.1Å; H306-D326 PolarHBondContact CE1-O 2.97Å; H306-D326 VanDerWaalsContact CE1-O 3.28Å; H306-D362 PolarHBondContact N-OD2 3.17Å
307R91Very high94.7Very high18 Ų1831.7 Ų31.77%0.06815%0.151CC..SBendtrans68.1-14.7177.6-50.2-172.3179.2-175.4-16.9117.6V305 L329 D338 F357 D362V305-R307 HydrophobicContact CB-CG 4.3Å; V305-R307 HydrophobicContact CG1-CG 3.76Å; R307-L329 HydrophobicContact CB-CB 4.3Å; R307-L329 VanDerWaalsContact CD-O 3.28Å; R307-L329 WeakPolarHBondContact CD-O 3.2Å; R307-D338 IonicContact CZ-OD2 2.95Å; R307-D338 IonicContact NH1-OD2 2.6Å; R307-D338 PolarHBondContact NH1-OD2 2.67Å; R307-F357 HydrophobicContact CB-CD1 4.1Å; R307-F357 HydrophobicContact CB-CE1 4.44Å; R307-F357 HydrophobicContact CG-CB 4.16Å; R307-F357 HydrophobicContact CG-CD1 3.86Å; R307-F357 HydrophobicContact CG-CG 4.08Å; R307-D362 PolarHBondContact N-OD1 3.25Å
308D90.9Very high94.4Very high17 Ų1734.6 Ų34.69%0.09117%0.168CC..  trans-136.245.7175.9-166.219.6000112.7H306 A310 R312 N313 L329 P343H306-D308 PolarHBondContact CE1-O 3.4Å; H306-D308 PolarHBondContact ND1-N 3.39Å; H306-D308 PolarHBondContact O-N 3.22Å; D308-A310 PolarHBondContact O-N 2.77Å; D308-R312 IonicContact OD1-CZ 2.84Å; D308-R312 IonicContact OD1-NH2 2.7Å; D308-R312 PolarHBondContact OD1-NH2 3.36Å; D308-R312 IonicContact OD2-CZ 2.98Å; D308-R312 IonicContact OD2-NH2 3.81Å; D308-R312 PolarHBondContact OD2-NH2 3.42Å; D308-N313 PolarHBondContact O-ND2 3.22Å; D308-N313 PolarHBondContact OD2-ND2 2.96Å; D308-L329 HydrophobicContact CB-CD1 4.17Å; D308-P343 VanDerWaalsContact OD1-CG 3.28Å; D308-P343 WeakPolarHBondContact OD1-CG 3.46Å
309L96.8Very high94.1Very high0 Ų039.1 Ų39.10%020%0.195CC..  trans-73.6116.7174.9-177.465.5000110.4V292 M296 V324 S365 Y366 L369V292-L309 HydrophobicContact CG1-CD1 4.17Å; M296-L309 HydrophobicContact CE-CD2 4.04Å; M296-L309 HydrophobicContact CG-CD1 4.37Å; M296-L309 HydrophobicContact CG-CD2 3.85Å; M296-L309 HydrophobicContact SD-CD1 3.92Å; M296-L309 HydrophobicContact SD-CD2 3.89Å; M296-L309 HydrophobicContact SD-CG 4.43Å; L309-V324 HydrophobicContact CD1-CG1 4.01Å; L309-V324 HydrophobicContact CD1-CG2 4.45Å; L309-S365 WeakPolarHBondContact O-CB 3.39Å; L309-Y366 HydrophobicContact CD2-CD2 4.15Å; L309-Y366 HydrophobicContact CD2-CG 4.46Å; L309-L369 HydrophobicContact CD1-CD1 3.7Å; L309-L369 HydrophobicContact CD2-CD1 4.42Å; L309-L369 HydrophobicContact CG-CD1 3.78Å
310A96.9Very high94.1Very high0 Ų040.5 Ų40.50%021%0.205CC..SBendtrans-157.4160177.200000109.8D308 R312 N313 V314 W346D308-A310 PolarHBondContact O-N 2.77Å; A310-R312 HydrophobicContact CB-CG 4.12Å; A310-R312 PolarHBondContact O-N 3.09Å; A310-R312 VanDerWaalsContact O-N 3.11Å; A310-N313 PolarHBondContact O-N 2.8Å; A310-V314 PolarHBondContact O-N 3.27Å; A310-W346 HydrophobicContact CB-CD2 4.12Å; A310-W346 HydrophobicContact CB-CG 4.01Å; A310-W346 HydrophobicContact CB-CZ2 4.45Å
311A97.8Very high94.2Very high0 Ų040.3 Ų40.30%021%0.207CC..G310 helixtrans-60.7-25.3-17900000113.5L268 V269 N313 V314 E372L268-A311 HydrophobicContact CB-CB 4.47Å; L268-A311 WeakPolarHBondContact CB-O 3.36Å; L268-A311 HydrophobicContact CD2-CB 4.39Å; L268-A311 HydrophobicContact CG-CB 4.47Å; V269-A311 HydrophobicContact CG2-CB 3.49Å; V269-A311 VanDerWaalsContact CG2-CB 3.49Å; A311-N313 PolarHBondContact O-N 2.89Å; A311-V314 PolarHBondContact O-N 3.18Å; A311-E372 HydrophobicContact CB-CB 3.98Å; A311-E372 HydrophobicContact CB-CG 4.47Å; A311-E372 PolarHBondContact N-OE2 2.81Å
312R95Very high94.3Very high85 Ų8536.5 Ų36.532%0.32118%0.18SC..G310 helixtrans-66.8-24.2174.569.3179.1-174.6-77-5.3113.5N267 V269 D308 A310N267-R312 WeakPolarHBondContact CB-O 3.45Å; V269-R312 HydrophobicContact CG2-CB 4.3Å; D308-R312 IonicContact OD1-CZ 2.84Å; D308-R312 IonicContact OD1-NH2 2.7Å; D308-R312 PolarHBondContact OD1-NH2 3.36Å; D308-R312 IonicContact OD2-CZ 2.98Å; D308-R312 IonicContact OD2-NH2 3.81Å; D308-R312 PolarHBondContact OD2-NH2 3.42Å; A310-R312 HydrophobicContact CB-CG 4.12Å; A310-R312 PolarHBondContact O-N 3.09Å; A310-R312 VanDerWaalsContact O-N 3.11Å
313N95.3Very high94.7Very high13 Ų1333.1 Ų33.17%0.0717%0.166CC..G310 helixtrans-100.813.3178.7-65.4-14.7000111.7D308 A310 A311 S325 D326D308-N313 PolarHBondContact O-ND2 3.22Å; D308-N313 PolarHBondContact OD2-ND2 2.96Å; A310-N313 PolarHBondContact O-N 2.8Å; A311-N313 PolarHBondContact O-N 2.89Å; N313-S325 VanDerWaalsContact C-OG 3.3Å; N313-S325 WeakPolarHBondContact O-CA 3.36Å; N313-S325 WeakPolarHBondContact O-CB 3.33Å; N313-S325 PolarHBondContact O-N 3Å; N313-S325 PolarHBondContact O-OG 3.32Å; N313-D326 HydrophobicContact CB-CB 4.35Å
314V98Very high95Very high0 Ų026 Ų260%013%0.134CC..EExtended strand (participates in β ladder)trans-108.9128.1169.11790000108.3N267 L268 V292 A310 A311 I316 A322 K323 L369N267-V314 CarbonylContact C-O 3.51Å; N267-V314 VanDerWaalsContact CA-O 3.24Å; N267-V314 WeakPolarHBondContact CA-O 3.26Å; L268-V314 HydrophobicContact CB-CB 3.98Å; L268-V314 HydrophobicContact CB-CG1 4.09Å; L268-V314 HydrophobicContact CD2-CB 4.1Å; L268-V314 HydrophobicContact CD2-CG1 3.89Å; L268-V314 PolarHBondContact N-O 3.11Å; V292-V314 HydrophobicContact CG2-CB 4.47Å; V292-V314 HydrophobicContact CG2-CG1 3.76Å; V292-V314 HydrophobicContact CG2-CG2 3.82Å; A310-V314 PolarHBondContact O-N 3.27Å; A311-V314 PolarHBondContact O-N 3.18Å; V314-I316 HydrophobicContact CG1-CD1 4.44Å; V314-A322 HydrophobicContact CG1-CB 3.81Å; V314-K323 WeakPolarHBondContact CA-O 3.49Å; V314-L369 HydrophobicContact CG2-CD1 3.84Å
315L97.4Very high95.1Very high43 Ų4326.2 Ų26.223%0.22514%0.137CC..EExtended strand (participates in β ladder)trans-110.5152179.8-57.7-175.8000111V245 M263 G266 N267 K323V245-L315 HydrophobicContact CG2-CB 4.4Å; V245-L315 HydrophobicContact CG2-CD1 4.12Å; M263-L315 HydrophobicContact CB-CB 3.58Å; M263-L315 HydrophobicContact CB-CD1 3.99Å; M263-L315 HydrophobicContact CB-CG 4.37Å; M263-L315 HydrophobicContact CE-CB 4.02Å; M263-L315 WeakPolarHBondContact CE-O 3.49Å; M263-L315 HydrophobicContact CG-CB 3.57Å; M263-L315 HydrophobicContact CG-CD1 3.77Å; M263-L315 HydrophobicContact CG-CG 4.33Å; G266-L315 CarbonylContact O-C 3.49Å; G266-L315 WeakPolarHBondContact O-CA 3.42Å; N267-L315 HydrophobicContact CB-CD2 3.86Å; L315-K323 PolarHBondContact N-O 3.01Å; L315-K323 PolarHBondContact O-N 3.3Å
316I97.9Very high94.7Very high0 Ų028 Ų280%015%0.147CC..EExtended strand (participates in β ladder)trans-114.2125.1-175.2-50.2-58000110.3M263 K265 G266 L268 F271 F288 V314 A322M263-I316 CarbonylContact C-O 3.58Å; M263-I316 VanDerWaalsContact CE-C 3.47Å; K265-I316 HydrophobicContact CB-CB 3.81Å; K265-I316 HydrophobicContact CB-CG2 3.88Å; K265-I316 WeakPolarHBondContact CB-O 3.47Å; K265-I316 HydrophobicContact CD-CG2 4.01Å; K265-I316 PolarHBondContact N-O 3.43Å; K265-I316 VanDerWaalsContact N-O 3.16Å; G266-I316 PolarHBondContact O-N 2.93Å; L268-I316 HydrophobicContact CB-CD1 4.12Å; L268-I316 HydrophobicContact CB-CG1 4.37Å; L268-I316 HydrophobicContact CD1-CD1 3.77Å; L268-I316 HydrophobicContact CD1-CG1 4.28Å; L268-I316 HydrophobicContact CG-CD1 4.41Å; F271-I316 HydrophobicContact CB-CG1 4.28Å; F271-I316 HydrophobicContact CG-CG1 4.26Å; F288-I316 HydrophobicContact CD1-CD1 4.2Å; F288-I316 HydrophobicContact CE1-CD1 3.97Å; F288-I316 HydrophobicContact CE1-CG2 4.33Å; F288-I316 HydrophobicContact CZ-CD1 4.43Å; V314-I316 HydrophobicContact CG1-CD1 4.44Å; I316-A322 HydrophobicContact CD1-CB 3.77Å
317S94.5Very high94Very high14 Ų1428.2 Ų28.210%0.09815%0.147CC..  trans-76.3173177.971.50000111.2K265 D319 S320 V321K265-S317 WeakPolarHBondContact CD-O 3.41Å; S317-D319 VanDerWaalsContact C-N 3.26Å; S317-D319 PolarHBondContact O-N 3.49Å; S317-D319 PolarHBondContact OG-N 3.4Å; S317-S320 PolarHBondContact O-N 2.77Å; S317-V321 PolarHBondContact N-O 2.78Å; S317-V321 WeakPolarHBondContact OG-CB 3.28Å; S317-V321 PolarHBondContact OG-N 2.95Å; S317-V321 VanDerWaalsContact OG-N 3.08Å; S317-V321 PolarHBondContact OG-O 2.6Å
318D91.6Very high92.8Very high105 Ų10528.3 Ų28.356%0.56115%0.154SC*.THydrogen-bonded Turntrans-60.6-36.7176.6-155.352.1000112.7T264 K265 S320T264-D318 WeakPolarHBondContact OG1-CA 3.23Å; T264-D318 WeakPolarHBondContact OG1-CB 3.36Å; T264-D318 PolarHBondContact OG1-N 3.34Å; T264-D318 PolarHBondContact OG1-OD1 2.71Å; T264-D318 VanDerWaalsContact OG1-OD1 3.12Å; K265-D318 VanDerWaalsContact CE-O 3.25Å; K265-D318 WeakPolarHBondContact CE-O 3.39Å; K265-D318 PolarHBondContact NZ-O 3.42Å; D318-S320 PolarHBondContact O-N 3.29Å; D318-S320 VanDerWaalsContact O-N 3.12Å
319D92.2Very high91.5Very high137 Ų13730 Ų3073%0.73316%0.163SC*.THydrogen-bonded Turntrans-77.99.9175.5-53.6-55.2000114.2S317 V321S317-D319 VanDerWaalsContact C-N 3.26Å; S317-D319 PolarHBondContact O-N 3.49Å; S317-D319 PolarHBondContact OG-N 3.4Å; D319-V321 VanDerWaalsContact C-N 3.31Å; D319-V321 HydrophobicContact CB-CG2 4.38Å; D319-V321 PolarHBondContact O-N 3.08Å
320S93.8Very high90Very high31 Ų3130.7 Ų30.722%0.21717%0.168CC..  trans61.835.4-177.5-40.80000113.7K265 F288 S317 D318K265-S320 PolarHBondContact NZ-OG 2.9Å; F288-S320 WeakPolarHBondContact CE1-O 3.41Å; S317-S320 PolarHBondContact O-N 2.77Å; D318-S320 PolarHBondContact O-N 3.29Å; D318-S320 VanDerWaalsContact O-N 3.12Å
321V97.2Very high88.7Confident44 Ų4434.2 Ų34.227%0.26718%0.184SC..  trans-91.2130.2169.9179.60000108.8S317 D319S317-V321 PolarHBondContact N-O 2.78Å; S317-V321 WeakPolarHBondContact OG-CB 3.28Å; S317-V321 PolarHBondContact OG-N 2.95Å; S317-V321 VanDerWaalsContact OG-N 3.08Å; S317-V321 PolarHBondContact OG-O 2.6Å; D319-V321 VanDerWaalsContact C-N 3.31Å; D319-V321 HydrophobicContact CB-CG2 4.38Å; D319-V321 PolarHBondContact O-N 3.08Å
322A98.4Very high87.2Confident0 Ų038.7 Ų38.70%021%0.206CC..EExtended strand (participates in β ladder)trans-82.6134.8174.300000111.3N243 F288 D291 V292 V314 I316N243-A322 PolarHBondContact ND2-O 2.86Å; F288-A322 HydrophobicContact CB-CB 4.36Å; F288-A322 HydrophobicContact CD1-CB 3.87Å; F288-A322 HydrophobicContact CG-CB 4.49Å; D291-A322 HydrophobicContact CB-CB 3.79Å; D291-A322 PolarHBondContact OD2-N 2.98Å; V292-A322 HydrophobicContact CG2-CB 4.22Å; V314-A322 HydrophobicContact CG1-CB 3.81Å; I316-A322 HydrophobicContact CD1-CB 3.77Å
323K98.4Very high85.7Confident29 Ų2938.4 Ų38.413%0.12621%0.211CC..EExtended strand (participates in β ladder)trans-131133.9175.5-51.8-168.5-178-171.30111.3K242 N243 V245 E261 M263 V314 L315K242-K323 WeakPolarHBondContact O-CD 3.4Å; K242-K323 WeakPolarHBondContact O-CE 3.38Å; N243-K323 CarbonylContact O-C 3.55Å; N243-K323 VanDerWaalsContact O-CA 3.26Å; N243-K323 WeakPolarHBondContact O-CA 3.46Å; V245-K323 HydrophobicContact CG2-CB 3.78Å; E261-K323 IonicContact OE1-NZ 2.7Å; E261-K323 PolarHBondContact OE1-NZ 3.04Å; E261-K323 IonicContact OE2-NZ 2.78Å; E261-K323 PolarHBondContact OE2-NZ 2.83Å; M263-K323 HydrophobicContact CE-CB 3.83Å; M263-K323 HydrophobicContact CE-CD 3.7Å; M263-K323 HydrophobicContact CE-CG 3.58Å; M263-K323 HydrophobicContact SD-CD 3.98Å; V314-K323 WeakPolarHBondContact CA-O 3.49Å; L315-K323 PolarHBondContact N-O 3.01Å; L315-K323 PolarHBondContact O-N 3.3Å
324V97.5Very high83.8Confident0 Ų039.1 Ų39.10%022%0.217CC..EExtended strand (participates in β ladder)trans-74.4138.8175.4-172.80000109.7N243 L244 V245 V292 M296 H306 L309N243-V324 PolarHBondContact O-N 3.45Å; L244-V324 HydrophobicContact CD2-CB 3.73Å; L244-V324 HydrophobicContact CD2-CG2 4.25Å; V245-V324 PolarHBondContact N-O 3.38Å; V292-V324 HydrophobicContact CB-CG2 4.42Å; V292-V324 HydrophobicContact CG1-CG2 3.95Å; V292-V324 HydrophobicContact CG2-CG2 4.44Å; M296-V324 HydrophobicContact SD-CG1 4.34Å; M296-V324 HydrophobicContact SD-CG2 4.48Å; H306-V324 WeakPolarHBondContact CD2-CG1 3.48Å; H306-V324 WeakPolarHBondContact NE2-CG1 2.98Å; L309-V324 HydrophobicContact CD1-CG1 4.01Å; L309-V324 HydrophobicContact CD1-CG2 4.45Å
325S92.6Very high81.8Confident13 Ų1349 Ų499%0.09126%0.26CS..  trans-136.7179.2-174.774.10000111.5H306 N313H306-S325 PolarHBondContact CE1-O 3.22Å; H306-S325 PolarHBondContact NE2-O 3.35Å; H306-S325 VanDerWaalsContact NE2-O 3.1Å; N313-S325 VanDerWaalsContact C-OG 3.3Å; N313-S325 WeakPolarHBondContact O-CA 3.36Å; N313-S325 WeakPolarHBondContact O-CB 3.33Å; N313-S325 PolarHBondContact O-N 3Å; N313-S325 PolarHBondContact O-OG 3.32Å
326D83.1Confident79.6Confident40 Ų4053 Ų5321%0.21428%0.277CS..  trans59.467.6175.8-151.416.7000114.5K218 H306 N313 G328K218-D326 IonicContact NZ-OD1 2.8Å; K218-D326 PolarHBondContact NZ-OD1 2.92Å; H306-D326 PolarHBondContact CE1-O 2.97Å; H306-D326 VanDerWaalsContact CE1-O 3.28Å; N313-D326 HydrophobicContact CB-CB 4.35Å; D326-G328 PolarHBondContact O-N 2.85Å
327F78.3Confident77.4Confident3 Ų357.8 Ų57.81%0.01331%0.307CS..G310 helixtrans-81.516.1177.3-53.1-78.3000113.1V235 M236 L239 L244 L299 L329 A330V235-F327 HydrophobicContact CG1-CB 4.33Å; M236-F327 HydrophobicContact CE-CD2 4.36Å; M236-F327 HydrophobicContact CG-CB 4.3Å; M236-F327 HydrophobicContact CG-CD2 3.69Å; M236-F327 HydrophobicContact CG-CE2 4.49Å; M236-F327 HydrophobicContact CG-CG 4.34Å; M236-F327 HydrophobicContact SD-CD2 4.27Å; L239-F327 HydrophobicContact CD1-CD1 3.82Å; L239-F327 HydrophobicContact CD1-CD2 4.14Å; L239-F327 HydrophobicContact CD1-CE1 3.74Å; L239-F327 HydrophobicContact CD1-CE2 4.06Å; L239-F327 HydrophobicContact CD1-CG 4.02Å; L239-F327 HydrophobicContact CD1-CZ 3.87Å; L244-F327 HydrophobicContact CB-CZ 4.18Å; L244-F327 HydrophobicContact CD1-CZ 4.45Å; L244-F327 HydrophobicContact CD2-CE1 4.26Å; L244-F327 HydrophobicContact CD2-CZ 4.01Å; L244-F327 HydrophobicContact CG-CZ 4.44Å; L299-F327 HydrophobicContact CD1-CE1 4.06Å; L299-F327 HydrophobicContact CD2-CE1 4.34Å; F327-L329 PolarHBondContact O-N 3.18Å; F327-L329 VanDerWaalsContact O-N 3.1Å; F327-A330 HydrophobicContact CB-CB 3.89Å; F327-A330 HydrophobicContact CD1-CB 4.44Å; F327-A330 VanDerWaalsContact O-CB 3.25Å; F327-A330 WeakPolarHBondContact O-CB 3.28Å; F327-A330 PolarHBondContact O-N 3.39Å
328G66.2Low75.5Confident20 Ų2059.8 Ų59.821%0.20632%0.316CS..G310 helixtrans-60.1-22.2-17500000114.6D326D326-G328 PolarHBondContact O-N 2.85Å
329L61.9Low73.7Confident52 Ų5263.8 Ų63.827%0.27233%0.329SS..G310 helixtrans-106.81.7173.8-61.1-179.7000113.3R307 D308 F327 K331R307-L329 HydrophobicContact CB-CB 4.3Å; R307-L329 VanDerWaalsContact CD-O 3.28Å; R307-L329 WeakPolarHBondContact CD-O 3.2Å; D308-L329 HydrophobicContact CB-CD1 4.17Å; F327-L329 PolarHBondContact O-N 3.18Å; F327-L329 VanDerWaalsContact O-N 3.1Å; L329-K331 PolarHBondContact O-N 3.44Å
330A65.2Low72.1Confident15 Ų1559 Ų5912%0.12431%0.308CS..  trans-69.7133-175.400000111.1V235 V305 F327V235-A330 HydrophobicContact CG1-CB 4.14Å; V305-A330 WeakPolarHBondContact O-CA 3.3Å; F327-A330 HydrophobicContact CB-CB 3.89Å; F327-A330 HydrophobicContact CD1-CB 4.44Å; F327-A330 VanDerWaalsContact O-CB 3.25Å; F327-A330 WeakPolarHBondContact O-CB 3.28Å; F327-A330 PolarHBondContact O-N 3.39Å
331K70.1Confident70.9Confident75 Ų7566.4 Ų66.433%0.32634%0.336SS..EExtended strand (participates in β ladder)trans-140.6155.5179.9-163.6175.7174.9-169.10110V305 L329 E336V305-K331 PolarHBondContact N-O 3.43Å; V305-K331 PolarHBondContact O-N 3.25Å; L329-K331 PolarHBondContact O-N 3.44Å; K331-E336 IonicContact NZ-OE2 2.74Å; K331-E336 PolarHBondContact NZ-OE2 2.87Å
332M67.5Low69.8Low94 Ų9466.3 Ų66.346%0.46333%0.334SS..EExtended strand (participates in β ladder)trans-56.3141.6166.3-71.5-68.3-177.700109.8L304 S334L304-M332 HydrophobicContact CD2-CE 3.92Å; L304-M332 HydrophobicContact CD2-CG 4.15Å; L304-M332 HydrophobicContact CD2-SD 3.64Å; L304-M332 HydrophobicContact CG-CE 4.48Å; L304-M332 HydrophobicContact CG-SD 4.22Å; M332-S334 PolarHBondContact O-N 3.48Å; M332-S334 VanDerWaalsContact O-N 3.1Å
333D62.6Low69.3Low79 Ų7967.3 Ų67.342%0.42234%0.34SS..  trans-57.1117.4176.5-165.7-4.6000110K303 V305K303-D333 PolarHBondContact O-N 3.4Å; V305-D333 HydrophobicContact CG2-CB 3.88Å
334S56.2Low69Low28 Ų2867.6 Ų67.620%0.19634%0.344CS..  trans-143.6141.4-173.173.10000109.4M332 E336M332-S334 PolarHBondContact O-N 3.48Å; M332-S334 VanDerWaalsContact O-N 3.1Å; S334-E336 PolarHBondContact O-N 3.4Å
335K55.1Low68.9Low208 Ų20868.1 Ų68.190%0.90435%0.347SS*.SBendtrans-76.45.2177.8-64.2-177.6-178.4174.50114.1
336E51.8Low69.1Low127 Ų12769 Ų6959%0.59335%0.348SS*.  trans-78.3143-177.5-65.5-179162.600112.2K331 S334K331-E336 IonicContact NZ-OE2 2.74Å; K331-E336 PolarHBondContact NZ-OE2 2.87Å; S334-E336 PolarHBondContact O-N 3.4Å
337T50.6Low69.7Low100 Ų10067.4 Ų67.461%0.61334%0.34SS*.  trans-80141.2176.151.30000111.1E355T337-E355 WeakPolarHBondContact CB-OE2 3.07Å; T337-E355 HydrophobicContact CG2-CB 4.22Å
338D56.3Low70.5Confident56 Ų5667.3 Ų67.330%0.29934%0.34SS..  trans-137.7128.5-173.1-160.1-14.5000111.1R307 A340 E355R307-D338 IonicContact CZ-OD2 2.95Å; R307-D338 IonicContact NH1-OD2 2.6Å; R307-D338 PolarHBondContact NH1-OD2 2.67Å; D338-A340 VanDerWaalsContact C-N 3.35Å; D338-A340 PolarHBondContact O-N 2.92Å; D338-E355 PolarHBondContact N-OE2 3.12Å; D338-E355 VanDerWaalsContact O-CD 3.3Å
339K53Low71.8Confident189 Ų18966.7 Ų66.782%0.82233%0.332SS*.  trans-93.832.5-171.1-66.8-172.3177.6-177.40113.7
340A59.5Low73.3Confident36 Ų3665.6 Ų65.630%0.29833%0.326SS..  trans-68.7150.7177.400000111.6D338 L342D338-A340 VanDerWaalsContact C-N 3.35Å; D338-A340 PolarHBondContact O-N 2.92Å; A340-L342 HydrophobicContact CB-CD2 4.18Å; A340-L342 WeakPolarHBondContact O-CG 3.49Å; A340-L342 PolarHBondContact O-N 2.96Å
341K67.1Low74.4Confident187 Ų18764.9 Ų64.981%0.81332%0.32SS*.  trans-66.8115.1167.2-77-178.1-178.1173.30108.2
342L74.1Confident75.1Confident41 Ų4162.9 Ų62.922%0.21531%0.312CS..  trans-95.5143.7-172.4-57177.1000112.7A340 V344 T347 F357A340-L342 HydrophobicContact CB-CD2 4.18Å; A340-L342 WeakPolarHBondContact O-CG 3.49Å; A340-L342 PolarHBondContact O-N 2.96Å; L342-V344 VanDerWaalsContact C-N 3.3Å; L342-V344 PolarHBondContact O-N 3.28Å; L342-T347 HydrophobicContact CD1-CG2 4.21Å; L342-F357 HydrophobicContact CD1-CE1 4.36Å; L342-F357 HydrophobicContact CD1-CZ 3.64Å; L342-F357 HydrophobicContact CD2-CE1 3.93Å; L342-F357 HydrophobicContact CD2-CE2 4.42Å; L342-F357 HydrophobicContact CD2-CZ 3.41Å; L342-F357 VanDerWaalsContact CD2-CZ 3.41Å; L342-F357 HydrophobicContact CG-CZ 4.15Å
343P88.6Confident75.9Confident21 Ų2165.3 Ų65.314%0.13632%0.32CS..  trans-72.882.6172.634.6-39.3000109.8D308 K345 W346 T347D308-P343 VanDerWaalsContact OD1-CG 3.28Å; D308-P343 WeakPolarHBondContact OD1-CG 3.46Å; P343-K345 VanDerWaalsContact C-N 3.27Å; P343-K345 PolarHBondContact O-N 3.47Å; P343-W346 HydrophobicContact CB-CE3 4.08Å; P343-W346 PolarHBondContact O-N 2.74Å; P343-T347 PolarHBondContact O-N 3.46Å; P343-T347 VanDerWaalsContact O-N 3.12Å; P343-T347 PolarHBondContact O-OG1 2.91Å
344V91.5Very high76.7Confident35 Ų3567.2 Ų67.221%0.21233%0.325CS..THydrogen-bonded Turntrans-48-43.7-166.9177.60000114L342 W346 T347 L352 L386L342-V344 VanDerWaalsContact C-N 3.3Å; L342-V344 PolarHBondContact O-N 3.28Å; V344-W346 VanDerWaalsContact C-N 3.27Å; V344-W346 PolarHBondContact O-N 3.06Å; V344-T347 PolarHBondContact O-N 3.49Å; V344-L352 HydrophobicContact CB-CD2 4.46Å; V344-L352 HydrophobicContact CG1-CD1 4.23Å; V344-L352 HydrophobicContact CG1-CD2 4.26Å; V344-L352 HydrophobicContact CG2-CD2 4.33Å; V344-L386 HydrophobicContact CB-CD2 4.31Å; V344-L386 HydrophobicContact CG1-CB 4.46Å
345K96.3Very high77.9Confident12 Ų1268.7 Ų68.75%0.05233%0.329CS..THydrogen-bonded Turntrans-65.6-25.4-177.8-67.1-175.2169.3-159.30113.8P343 Q379 P380 Y381 L386 V389P343-K345 VanDerWaalsContact C-N 3.27Å; P343-K345 PolarHBondContact O-N 3.47Å; K345-Q379 VanDerWaalsContact NZ-OE1 3.11Å; K345-P380 HydrophobicContact CB-CB 4.45Å; K345-P380 WeakPolarHBondContact CD-O 3.27Å; K345-P380 WeakPolarHBondContact CE-O 3.4Å; K345-P380 PolarHBondContact NZ-O 2.94Å; K345-Y381 HydrophobicContact CB-CD2 4.03Å; K345-Y381 HydrophobicContact CB-CE2 4.3Å; K345-Y381 HydrophobicContact CD-CD2 4.46Å; K345-Y381 HydrophobicContact CG-CD2 4.16Å; K345-Y381 PolarHBondContact NZ-O 3.35Å; K345-Y381 WeakPolarHBondContact O-CE2 3.47Å; K345-L386 HydrophobicContact CD-CD2 4.36Å; K345-L386 HydrophobicContact CG-CD2 3.95Å; K345-V389 HydrophobicContact CG-CG2 4.45Å
346W97Very high79.2Confident31 Ų3164.4 Ų64.412%0.11731%0.31CS..THydrogen-bonded Turntrans-99.4-14.7178.9-67.7-98.9000112.7A310 P343 V344 W364 S365 V368 E372 P380A310-W346 HydrophobicContact CB-CD2 4.12Å; A310-W346 HydrophobicContact CB-CG 4.01Å; A310-W346 HydrophobicContact CB-CZ2 4.45Å; P343-W346 HydrophobicContact CB-CE3 4.08Å; P343-W346 PolarHBondContact O-N 2.74Å; V344-W346 VanDerWaalsContact C-N 3.27Å; V344-W346 PolarHBondContact O-N 3.06Å; W346-W364 VanDerWaalsContact O-CD1 3.31Å; W346-S365 WeakPolarHBondContact O-CA 3.34Å; W346-S365 PolarHBondContact O-OG 2.91Å; W346-V368 VanDerWaalsContact CD1-CG1 3.45Å; W346-V368 HydrophobicContact CD2-CG1 4.45Å; W346-V368 HydrophobicContact CG-CB 4.45Å; W346-V368 HydrophobicContact CG-CG1 3.98Å; W346-E372 WeakPolarHBondContact CZ2-OE1 3.37Å; W346-E372 VanDerWaalsContact NE1-CD 3.32Å; W346-E372 PolarHBondContact NE1-OE2 3Å; W346-P380 HydrophobicContact CH2-CG 4.38Å; W346-P380 HydrophobicContact CZ2-CG 3.69Å
347T94.8Very high80.9Confident6 Ų658.8 Ų58.84%0.03728%0.284CS..SBendtrans-82.3134.7-171.2-54.30000111.4L342 P343 V344 A351 L352L342-T347 HydrophobicContact CD1-CG2 4.21Å; P343-T347 PolarHBondContact O-N 3.46Å; P343-T347 VanDerWaalsContact O-N 3.12Å; P343-T347 PolarHBondContact O-OG1 2.91Å; V344-T347 PolarHBondContact O-N 3.49Å; T347-A351 HydrophobicContact CG2-CB 3.59Å; T347-L352 HydrophobicContact CG2-CD2 3.73Å; T347-L352 HydrophobicContact CG2-CG 3.69Å
348A95.7Very high83Confident1 Ų155.3 Ų55.31%0.00826%0.263CS..  trans-62.9150.9177.200000112.6E350 A351 L352 W364A348-E350 VanDerWaalsContact C-N 3.3Å; A348-E350 VanDerWaalsContact CB-OE1 3.24Å; A348-E350 WeakPolarHBondContact CB-OE1 3.43Å; A348-E350 WeakPolarHBondContact CB-OE2 3.19Å; A348-E350 PolarHBondContact O-N 2.74Å; A348-A351 HydrophobicContact CB-CB 4.43Å; A348-A351 PolarHBondContact O-N 3.21Å; A348-L352 PolarHBondContact O-N 3.33Å; A348-W364 HydrophobicContact CB-CB 3.7Å; A348-W364 HydrophobicContact CB-CD2 4.14Å; A348-W364 HydrophobicContact CB-CG 3.7Å
349P93.5Very high84.8Confident7 Ų753.5 Ų53.55%0.04525%0.254CS..Hα-helixtrans-57.4-39.9-176.5-19.627.8000113.3A351 L352 K353 W364 V393P349-A351 VanDerWaalsContact C-N 3.34Å; P349-A351 PolarHBondContact O-N 2.79Å; P349-L352 PolarHBondContact O-N 3.43Å; P349-K353 WeakPolarHBondContact O-CB 3.47Å; P349-K353 PolarHBondContact O-N 2.82Å; P349-W364 HydrophobicContact CG-CE3 4.37Å; P349-W364 HydrophobicContact CG-CH2 3.66Å; P349-W364 HydrophobicContact CG-CZ2 4.08Å; P349-W364 HydrophobicContact CG-CZ3 3.82Å; P349-V393 HydrophobicContact CG-CG1 3.77Å
350E92.3Very high86.9Confident30 Ų3046.9 Ų46.914%0.1423%0.225CC..Hα-helixtrans-69.4-30.8178.672-75.9-178.100113.3A348 K354 P421 R424A348-E350 VanDerWaalsContact C-N 3.3Å; A348-E350 VanDerWaalsContact CB-OE1 3.24Å; A348-E350 WeakPolarHBondContact CB-OE1 3.43Å; A348-E350 WeakPolarHBondContact CB-OE2 3.19Å; A348-E350 PolarHBondContact O-N 2.74Å; E350-K354 WeakPolarHBondContact O-CB 3.49Å; E350-K354 PolarHBondContact O-N 3.05Å; E350-P421 HydrophobicContact CB-CG 4.42Å; E350-P421 VanDerWaalsContact CD-CG 3.49Å; E350-P421 HydrophobicContact CG-CG 3.78Å; E350-R424 IonicContact OE1-CZ 3.98Å; E350-R424 IonicContact OE1-NH1 2.74Å; E350-R424 PolarHBondContact OE1-NH1 3.23Å; E350-R424 IonicContact OE1-NH2 2.68Å; E350-R424 PolarHBondContact OE1-NH2 2.9Å; E350-R424 IonicContact OE2-CZ 2.79Å; E350-R424 IonicContact OE2-NH1 3.74Å; E350-R424 IonicContact OE2-NH2 3.8Å; E350-R424 PolarHBondContact OE2-NH2 2.7Å
351A88.6Confident88.7Confident0 Ų045.3 Ų45.30%021%0.212CC..Hα-helixtrans-74.9-38.5175.600000110.8T347 A348 P349 E355 F357T347-A351 HydrophobicContact CG2-CB 3.59Å; A348-A351 HydrophobicContact CB-CB 4.43Å; A348-A351 PolarHBondContact O-N 3.21Å; P349-A351 VanDerWaalsContact C-N 3.34Å; P349-A351 PolarHBondContact O-N 2.79Å; A351-E355 WeakPolarHBondContact O-CA 3.42Å; A351-E355 PolarHBondContact O-N 3.47Å; A351-F357 HydrophobicContact CB-CD1 4.06Å; A351-F357 HydrophobicContact CB-CE1 3.86Å; A351-F357 HydrophobicContact CB-CZ 4.27Å
352L85.9Confident90.1Very high32 Ų3236.5 Ų36.517%0.16817%0.174CC..Hα-helixtrans-65.2-37.1173.4-71.9175.6000113.6V344 T347 A348 P349 K390V344-L352 HydrophobicContact CB-CD2 4.46Å; V344-L352 HydrophobicContact CG1-CD1 4.23Å; V344-L352 HydrophobicContact CG1-CD2 4.26Å; V344-L352 HydrophobicContact CG2-CD2 4.33Å; T347-L352 HydrophobicContact CG2-CD2 3.73Å; T347-L352 HydrophobicContact CG2-CG 3.69Å; A348-L352 PolarHBondContact O-N 3.33Å; P349-L352 PolarHBondContact O-N 3.43Å; L352-K390 HydrophobicContact CD1-CG 4.45Å
353K83.5Confident91.3Very high146 Ų14634.5 Ų34.564%0.63516%0.164SC*.Hα-helixtrans-89.9-38.2-173.7-175.4170.7-176.5166.10113.8P349P349-K353 WeakPolarHBondContact O-CB 3.47Å; P349-K353 PolarHBondContact O-N 2.82Å
354K80.5Confident91.8Very high119 Ų11933.6 Ų33.652%0.51716%0.157SC..Hα-helixtrans-122.34.5-169.5-57.6-177.3-178.9177.80113E350 K356E350-K354 WeakPolarHBondContact O-CB 3.49Å; E350-K354 PolarHBondContact O-N 3.05Å; K354-K356 HydrophobicContact CB-CB 4.5Å; K354-K356 HydrophobicContact CB-CD 4.07Å; K354-K356 HydrophobicContact CB-CG 3.87Å; K354-K356 HydrophobicContact CD-CD 4.42Å; K354-K356 WeakPolarHBondContact O-CG 3.48Å; K354-K356 PolarHBondContact O-N 3.01Å; K354-K356 VanDerWaalsContact O-N 3.13Å
355E79.9Confident92.1Very high59 Ų5932.1 Ų32.128%0.27615%0.149SC..  trans53.431.9-175.2-59.8177.7176.600112.3T337 D338 A351T337-E355 WeakPolarHBondContact CB-OE2 3.07Å; T337-E355 HydrophobicContact CG2-CB 4.22Å; D338-E355 PolarHBondContact N-OE2 3.12Å; D338-E355 VanDerWaalsContact O-CD 3.3Å; A351-E355 WeakPolarHBondContact O-CA 3.42Å; A351-E355 PolarHBondContact O-N 3.47Å
356K83.4Confident92.2Very high117 Ų11731.6 Ų31.651%0.50915%0.147SC..  trans-96.397.9-179.4-69.1-172.9-178.5-170.50110.9K354K354-K356 HydrophobicContact CB-CB 4.5Å; K354-K356 HydrophobicContact CB-CD 4.07Å; K354-K356 HydrophobicContact CB-CG 3.87Å; K354-K356 HydrophobicContact CD-CD 4.42Å; K354-K356 WeakPolarHBondContact O-CG 3.48Å; K354-K356 PolarHBondContact O-N 3.01Å; K354-K356 VanDerWaalsContact O-N 3.13Å
357F87.6Confident92.3Very high10 Ų1030.1 Ų30.14%0.04414%0.141CC..  trans-90.7140.7173.6-59.8-86000110.8V305 R307 L342 A351V305-F357 HydrophobicContact CG1-CB 4.23Å; R307-F357 HydrophobicContact CB-CD1 4.1Å; R307-F357 HydrophobicContact CB-CE1 4.44Å; R307-F357 HydrophobicContact CG-CB 4.16Å; R307-F357 HydrophobicContact CG-CD1 3.86Å; R307-F357 HydrophobicContact CG-CG 4.08Å; L342-F357 HydrophobicContact CD1-CE1 4.36Å; L342-F357 HydrophobicContact CD1-CZ 3.64Å; L342-F357 HydrophobicContact CD2-CE1 3.93Å; L342-F357 HydrophobicContact CD2-CE2 4.42Å; L342-F357 HydrophobicContact CD2-CZ 3.41Å; L342-F357 VanDerWaalsContact CD2-CZ 3.41Å; L342-F357 HydrophobicContact CG-CZ 4.15Å; A351-F357 HydrophobicContact CB-CD1 4.06Å; A351-F357 HydrophobicContact CB-CE1 3.86Å; A351-F357 HydrophobicContact CB-CZ 4.27Å
358S93.3Very high92.5Very high26 Ų2629.8 Ų29.818%0.18214%0.139CC..  trans-157.6173.2176.861.50000110.1V305 K360 S361 D362V305-S358 WeakPolarHBondContact CG1-O 3.28Å; S358-K360 PolarHBondContact O-N 2.89Å; S358-K360 VanDerWaalsContact O-N 3.09Å; S358-K360 PolarHBondContact OG-N 3.29Å; S358-S361 PolarHBondContact N-OG 2.96Å; S358-S361 PolarHBondContact O-N 3.32Å; S358-S361 PolarHBondContact O-OG 3Å; S358-S361 PolarHBondContact OG-N 2.67Å; S358-D362 PolarHBondContact O-N 2.98Å
359T95.1Very high92.7Very high19 Ų1929.8 Ų29.812%0.11714%0.139CC..Hα-helixtrans-57.1-28.617270.60000111.7E300 D362 V363E300-T359 HydrophobicContact CB-CG2 4.34Å; E300-T359 HydrophobicContact CG-CG2 4.13Å; E300-T359 PolarHBondContact OE1-OG1 3.1Å; E300-T359 VanDerWaalsContact OE1-OG1 3.1Å; T359-D362 WeakPolarHBondContact O-CB 3.07Å; T359-D362 PolarHBondContact O-N 3.12Å; T359-V363 WeakPolarHBondContact O-CG2 3.31Å; T359-V363 PolarHBondContact O-N 3.39Å
360K97.4Very high92.9Very high49 Ų4929.5 Ų29.521%0.21314%0.137CC..Hα-helixtrans-72.5-27.7176.2-58.3-58.2-178.9177.30114.1S358 W364 P421 R424 P425S358-K360 PolarHBondContact O-N 2.89Å; S358-K360 VanDerWaalsContact O-N 3.09Å; S358-K360 PolarHBondContact OG-N 3.29Å; K360-W364 PolarHBondContact O-N 3.23Å; K360-P421 HydrophobicContact CB-CB 3.89Å; K360-P421 WeakPolarHBondContact CD-O 3.46Å; K360-P421 WeakPolarHBondContact CG-O 3.23Å; K360-R424 HydrophobicContact CD-CB 4.32Å; K360-R424 PolarHBondContact NZ-O 3.17Å; K360-R424 WeakPolarHBondContact O-CD 3.39Å; K360-R424 PolarHBondContact O-NH1 3.49Å; K360-P425 PolarHBondContact NZ-O 2.97Å
361S96.6Very high93.2Very high3 Ų328.9 Ų28.92%0.02113%0.134CC..Hα-helixtrans-73.6-32.817059.30000111S358 V363 W364 S365S358-S361 PolarHBondContact N-OG 2.96Å; S358-S361 PolarHBondContact O-N 3.32Å; S358-S361 PolarHBondContact O-OG 3Å; S358-S361 PolarHBondContact OG-N 2.67Å; S361-V363 VanDerWaalsContact C-N 3.34Å; S361-W364 WeakPolarHBondContact O-CB 3.37Å; S361-W364 PolarHBondContact O-N 3.46Å; S361-S365 PolarHBondContact O-N 2.98Å; S361-S365 VanDerWaalsContact O-N 3.16Å; S361-S365 PolarHBondContact O-OG 3.41Å
362D97.6Very high93.7Very high2 Ų229.2 Ų29.21%0.01114%0.135CC..Hα-helixtrans-67.8-34.2172.2-72.8-19.3000112.2M296 V305 H306 R307 S358 T359 W364 S365 Y366 F427M296-D362 HydrophobicContact CE-CB 3.81Å; V305-D362 WeakPolarHBondContact CA-OD2 3.33Å; V305-D362 VanDerWaalsContact CG1-OD2 3.3Å; V305-D362 WeakPolarHBondContact CG1-OD2 3.44Å; H306-D362 PolarHBondContact N-OD2 3.17Å; R307-D362 PolarHBondContact N-OD1 3.25Å; S358-D362 PolarHBondContact O-N 2.98Å; T359-D362 WeakPolarHBondContact O-CB 3.07Å; T359-D362 PolarHBondContact O-N 3.12Å; D362-W364 VanDerWaalsContact C-N 3.26Å; D362-W364 PolarHBondContact O-N 2.84Å; D362-S365 WeakPolarHBondContact O-CB 3.44Å; D362-S365 PolarHBondContact O-N 3.45Å; D362-Y366 WeakPolarHBondContact O-CB 3.38Å; D362-Y366 PolarHBondContact O-N 3.1Å; D362-F427 HydrophobicContact CB-CE2 4.24Å; D362-F427 HydrophobicContact CB-CZ 4.24Å
363V98.6Very high94.3Very high0 Ų027.7 Ų27.70%013%0.127CC..Hα-helixtrans-59.6-38.4172.1169.70000111.3T359 S361 Y366 G367 C416 R424 F427 L430T359-V363 WeakPolarHBondContact O-CG2 3.31Å; T359-V363 PolarHBondContact O-N 3.39Å; S361-V363 VanDerWaalsContact C-N 3.34Å; V363-Y366 WeakPolarHBondContact O-CB 3.46Å; V363-Y366 PolarHBondContact O-N 2.98Å; V363-G367 PolarHBondContact O-N 2.75Å; V363-G367 VanDerWaalsContact O-N 3.08Å; V363-C416 HydrophobicContact CG1-CB 4.12Å; V363-C416 VanDerWaalsContact O-CB 3.29Å; V363-C416 WeakPolarHBondContact O-CB 3.36Å; V363-R424 HydrophobicContact CG1-CB 3.9Å; V363-F427 HydrophobicContact CG2-CD2 4Å; V363-F427 HydrophobicContact CG2-CE1 4.41Å; V363-F427 HydrophobicContact CG2-CE2 3.61Å; V363-F427 HydrophobicContact CG2-CZ 3.84Å; V363-L430 HydrophobicContact CG1-CD1 3.97Å; V363-L430 HydrophobicContact CG2-CD1 4.37Å
364W98.6Very high95Very high1 Ų121 Ų210%0.00410%0.098CC..Hα-helixtrans-62.7-49.9173.2176.3-75.5000111.5W346 A348 P349 K360 S361 D362 Y366 G367 V368 V393 R398 W417W346-W364 VanDerWaalsContact O-CD1 3.31Å; A348-W364 HydrophobicContact CB-CB 3.7Å; A348-W364 HydrophobicContact CB-CD2 4.14Å; A348-W364 HydrophobicContact CB-CG 3.7Å; P349-W364 HydrophobicContact CG-CE3 4.37Å; P349-W364 HydrophobicContact CG-CH2 3.66Å; P349-W364 HydrophobicContact CG-CZ2 4.08Å; P349-W364 HydrophobicContact CG-CZ3 3.82Å; K360-W364 PolarHBondContact O-N 3.23Å; S361-W364 WeakPolarHBondContact O-CB 3.37Å; S361-W364 PolarHBondContact O-N 3.46Å; D362-W364 VanDerWaalsContact C-N 3.26Å; D362-W364 PolarHBondContact O-N 2.84Å; W364-Y366 PolarHBondContact O-N 3.39Å; W364-G367 WeakPolarHBondContact O-CA 3.45Å; W364-G367 PolarHBondContact O-N 3.22Å; W364-V368 PolarHBondContact O-N 2.89Å; W364-V368 VanDerWaalsContact O-N 3.15Å; W364-V393 HydrophobicContact CH2-CG1 3.62Å; W364-V393 HydrophobicContact CZ2-CG1 3.47Å; W364-V393 VanDerWaalsContact CZ2-CG1 3.47Å; W364-R398 VanDerWaalsContact CH2-CZ 3.48Å; W364-W417 AromaticContact CD2-CD1 3.83Å; W364-W417 AromaticContact CE2-CD1 3.94Å; W364-W417 HydrophobicContact CE3-CB 4.16Å; W364-W417 HydrophobicContact CH2-CB 4.19Å; W364-W417 HydrophobicContact CZ3-CB 3.9Å; W364-W417 WeakPolarHBondContact CZ3-O 3.27Å; W364-W417 PolarHBondContact O-NE1 3.35Å
365S98.4Very high95.8Very high5 Ų515.3 Ų15.34%0.0357%0.073CC..Hα-helixtrans-56.6-38.8176.8-51.60000111.4L309 W346 S361 D362 G367 V368 L369L309-S365 WeakPolarHBondContact O-CB 3.39Å; W346-S365 WeakPolarHBondContact O-CA 3.34Å; W346-S365 PolarHBondContact O-OG 2.91Å; S361-S365 PolarHBondContact O-N 2.98Å; S361-S365 VanDerWaalsContact O-N 3.16Å; S361-S365 PolarHBondContact O-OG 3.41Å; D362-S365 WeakPolarHBondContact O-CB 3.44Å; D362-S365 PolarHBondContact O-N 3.45Å; S365-G367 PolarHBondContact O-N 2.86Å; S365-V368 WeakPolarHBondContact O-CB 3.44Å; S365-V368 PolarHBondContact O-N 3.16Å; S365-V368 VanDerWaalsContact O-N 3.15Å; S365-L369 WeakPolarHBondContact O-CB 3.5Å; S365-L369 PolarHBondContact O-N 3.21Å
366Y98.8Very high96.7Very high0 Ų013.8 Ų13.80%07%0.065CC..Hα-helixtrans-61.8-40.8174.4-178.9-111.5000112.3S289 V292 C293 L309 D362 V363 W364 V368 L369 L370 F427 L430 L434S289-Y366 PolarHBondContact O-OH 3.15Å; V292-Y366 HydrophobicContact CB-CE2 4.21Å; V292-Y366 HydrophobicContact CG1-CD2 3.95Å; V292-Y366 HydrophobicContact CG1-CE2 3.81Å; C293-Y366 HydrophobicContact CB-CE2 4.33Å; C293-Y366 WeakPolarHBondContact CB-OH 3.5Å; L309-Y366 HydrophobicContact CD2-CD2 4.15Å; L309-Y366 HydrophobicContact CD2-CG 4.46Å; D362-Y366 WeakPolarHBondContact O-CB 3.38Å; D362-Y366 PolarHBondContact O-N 3.1Å; V363-Y366 WeakPolarHBondContact O-CB 3.46Å; V363-Y366 PolarHBondContact O-N 2.98Å; W364-Y366 PolarHBondContact O-N 3.39Å; Y366-V368 VanDerWaalsContact C-N 3.31Å; Y366-V368 PolarHBondContact O-N 3.11Å; Y366-L369 HydrophobicContact CD2-CD2 4.26Å; Y366-L369 HydrophobicContact CE2-CD2 4.24Å; Y366-L369 WeakPolarHBondContact O-CB 3.47Å; Y366-L369 PolarHBondContact O-N 3.44Å; Y366-L370 HydrophobicContact CD1-CD1 4.15Å; Y366-L370 HydrophobicContact CD1-CG 4.32Å; Y366-L370 HydrophobicContact CE1-CD1 3.67Å; Y366-L370 HydrophobicContact CE1-CD2 4.2Å; Y366-L370 HydrophobicContact CE1-CG 3.91Å; Y366-L370 HydrophobicContact CE2-CD2 4.2Å; Y366-L370 HydrophobicContact CE2-CG 4.33Å; Y366-L370 WeakPolarHBondContact O-CG 3.49Å; Y366-L370 PolarHBondContact O-N 2.83Å; Y366-F427 HydrophobicContact CD1-CE1 4.06Å; Y366-F427 HydrophobicContact CD2-CE1 4.21Å; Y366-F427 AromaticContact CG-CE1 3.76Å; Y366-F427 HydrophobicContact CG-CE1 3.76Å; Y366-L430 HydrophobicContact CD1-CD1 3.94Å; Y366-L430 HydrophobicContact CE1-CD1 4.19Å; Y366-L434 HydrophobicContact CE1-CD1 4.36Å; Y366-L434 WeakPolarHBondContact OH-CD1 3.45Å
367G98.8Very high97.3Very high0 Ų08.2 Ų8.20%04%0.041CC..Hα-helixtrans-59.5-40.617200000112.9V363 W364 S365 L370 W371 W417V363-G367 PolarHBondContact O-N 2.75Å; V363-G367 VanDerWaalsContact O-N 3.08Å; W364-G367 WeakPolarHBondContact O-CA 3.45Å; W364-G367 PolarHBondContact O-N 3.22Å; S365-G367 PolarHBondContact O-N 2.86Å; G367-L370 PolarHBondContact O-N 3.49Å; G367-W371 PolarHBondContact O-N 3.01Å; G367-W371 VanDerWaalsContact O-N 3.11Å; G367-W417 VanDerWaalsContact C-CZ2 3.47Å; G367-W417 WeakPolarHBondContact O-CZ2 3.41Å
368V98.8Very high97.7Very high0 Ų013.9 Ų13.90%06%0.062CC..Hα-helixtrans-66.7-41.4174.9-1770000111.1W346 W364 S365 Y366 W371 E372 P380 M399 W417W346-V368 VanDerWaalsContact CD1-CG1 3.45Å; W346-V368 HydrophobicContact CD2-CG1 4.45Å; W346-V368 HydrophobicContact CG-CB 4.45Å; W346-V368 HydrophobicContact CG-CG1 3.98Å; W364-V368 PolarHBondContact O-N 2.89Å; W364-V368 VanDerWaalsContact O-N 3.15Å; S365-V368 WeakPolarHBondContact O-CB 3.44Å; S365-V368 PolarHBondContact O-N 3.16Å; S365-V368 VanDerWaalsContact O-N 3.15Å; Y366-V368 VanDerWaalsContact C-N 3.31Å; Y366-V368 PolarHBondContact O-N 3.11Å; V368-W371 WeakPolarHBondContact O-CB 3.35Å; V368-W371 PolarHBondContact O-N 3.08Å; V368-W371 VanDerWaalsContact O-N 3.15Å; V368-E372 PolarHBondContact O-N 3.38Å; V368-P380 HydrophobicContact CG1-CB 3.81Å; V368-P380 HydrophobicContact CG1-CG 3.62Å; V368-M399 HydrophobicContact CG1-CE 4.28Å; V368-W417 HydrophobicContact CG2-CZ2 4.46Å
369L98.8Very high97.8Very high0 Ų018.1 Ų18.10%08%0.079CC..Hα-helixtrans-60.9-43.3174.5176.7159.5000111.9V292 L309 V314 S365 Y366 W371 E372 I373V292-L369 HydrophobicContact CG1-CD1 3.91Å; V292-L369 HydrophobicContact CG1-CD2 4.19Å; L309-L369 HydrophobicContact CD1-CD1 3.7Å; L309-L369 HydrophobicContact CD2-CD1 4.42Å; L309-L369 HydrophobicContact CG-CD1 3.78Å; V314-L369 HydrophobicContact CG2-CD1 3.84Å; S365-L369 WeakPolarHBondContact O-CB 3.5Å; S365-L369 PolarHBondContact O-N 3.21Å; Y366-L369 HydrophobicContact CD2-CD2 4.26Å; Y366-L369 HydrophobicContact CE2-CD2 4.24Å; Y366-L369 WeakPolarHBondContact O-CB 3.47Å; Y366-L369 PolarHBondContact O-N 3.44Å; L369-W371 VanDerWaalsContact C-N 3.27Å; L369-W371 PolarHBondContact O-N 3.42Å; L369-E372 WeakPolarHBondContact O-CB 3.48Å; L369-E372 PolarHBondContact O-N 2.8Å; L369-E372 VanDerWaalsContact O-N 3.1Å; L369-I373 HydrophobicContact CD2-CD1 3.44Å; L369-I373 VanDerWaalsContact CD2-CD1 3.44Å; L369-I373 HydrophobicContact CD2-CG1 4.06Å; L369-I373 WeakPolarHBondContact O-CG1 3.41Å; L369-I373 PolarHBondContact O-N 3.16Å
370L98.8Very high97.9Very high2 Ų217.3 Ų17.31%0.017%0.074CC..Hα-helixtrans-57.3-44.5173.2-73.1-178.2000110.6S289 Y366 G367 E372 I373 F374 I412 M413S289-L370 VanDerWaalsContact CB-CD2 3.45Å; S289-L370 VanDerWaalsContact OG-CD2 3.23Å; S289-L370 WeakPolarHBondContact OG-CD2 3.46Å; Y366-L370 HydrophobicContact CD1-CD1 4.15Å; Y366-L370 HydrophobicContact CD1-CG 4.32Å; Y366-L370 HydrophobicContact CE1-CD1 3.67Å; Y366-L370 HydrophobicContact CE1-CD2 4.2Å; Y366-L370 HydrophobicContact CE1-CG 3.91Å; Y366-L370 HydrophobicContact CE2-CD2 4.2Å; Y366-L370 HydrophobicContact CE2-CG 4.33Å; Y366-L370 WeakPolarHBondContact O-CG 3.49Å; Y366-L370 PolarHBondContact O-N 2.83Å; G367-L370 PolarHBondContact O-N 3.49Å; L370-E372 VanDerWaalsContact C-N 3.31Å; L370-E372 PolarHBondContact O-N 3.15Å; L370-I373 WeakPolarHBondContact O-CB 3.43Å; L370-I373 PolarHBondContact O-N 3.35Å; L370-I373 VanDerWaalsContact O-N 3.16Å; L370-F374 VanDerWaalsContact O-CD2 3.31Å; L370-F374 WeakPolarHBondContact O-CD2 3.36Å; L370-F374 PolarHBondContact O-N 2.97Å; L370-I412 HydrophobicContact CD1-CG2 3.78Å; L370-M413 HydrophobicContact CB-CE 3.96Å; L370-M413 HydrophobicContact CB-CG 3.76Å; L370-M413 HydrophobicContact CB-SD 4.42Å; L370-M413 HydrophobicContact CD1-CG 4.14Å
371W98.7Very high97.9Very high17 Ų1715 Ų156%0.0646%0.064CC..Hα-helixtrans-59.2-43.1175.3-170.397000111.6G367 V368 L369 I373 F374 A375 R378 P380 M399 E400 P402 M413 W417G367-W371 PolarHBondContact O-N 3.01Å; G367-W371 VanDerWaalsContact O-N 3.11Å; V368-W371 WeakPolarHBondContact O-CB 3.35Å; V368-W371 PolarHBondContact O-N 3.08Å; V368-W371 VanDerWaalsContact O-N 3.15Å; L369-W371 VanDerWaalsContact C-N 3.27Å; L369-W371 PolarHBondContact O-N 3.42Å; W371-I373 VanDerWaalsContact C-N 3.34Å; W371-I373 PolarHBondContact O-N 2.98Å; W371-F374 PolarHBondContact O-N 3.04Å; W371-A375 HydrophobicContact CD2-CB 4.2Å; W371-A375 HydrophobicContact CE3-CB 3.87Å; W371-A375 HydrophobicContact CH2-CB 3.92Å; W371-A375 HydrophobicContact CZ2-CB 4.24Å; W371-A375 HydrophobicContact CZ3-CB 3.72Å; W371-A375 WeakPolarHBondContact O-CB 3.3Å; W371-A375 PolarHBondContact O-N 2.99Å; W371-R378 HydrophobicContact CH2-CB 4.2Å; W371-R378 HydrophobicContact CZ3-CB 4.13Å; W371-P380 HydrophobicContact CE3-CB 4.48Å; W371-P380 HydrophobicContact CE3-CG 4.42Å; W371-M399 HydrophobicContact CB-CE 3.87Å; W371-M399 HydrophobicContact CD2-CE 3.94Å; W371-M399 HydrophobicContact CD2-SD 3.88Å; W371-M399 HydrophobicContact CE3-CE 4.46Å; W371-M399 HydrophobicContact CE3-SD 4.3Å; W371-M399 HydrophobicContact CG-CE 3.65Å; W371-M399 HydrophobicContact CG-SD 4.15Å; W371-M399 HydrophobicContact CZ2-SD 4.37Å; W371-E400 PolarHBondContact NE1-O 3.3Å; W371-P402 HydrophobicContact CD2-CG 4.32Å; W371-P402 HydrophobicContact CG-CG 4.06Å; W371-M413 HydrophobicContact CB-SD 4.08Å; W371-W417 HydrophobicContact CB-CH2 4.08Å; W371-W417 HydrophobicContact CB-CZ2 4.11Å; W371-W417 HydrophobicContact CG-CH2 4.34Å
372E98.6Very high97.8Very high6 Ų618.4 Ų18.43%0.0289%0.086CC..Hα-helixtrans-59.1-43.7174.1-64.9179.698.100112.2A311 W346 V368 L369 L370 A375 Y376 G377 P380A311-E372 HydrophobicContact CB-CB 3.98Å; A311-E372 HydrophobicContact CB-CG 4.47Å; A311-E372 PolarHBondContact N-OE2 2.81Å; W346-E372 WeakPolarHBondContact CZ2-OE1 3.37Å; W346-E372 VanDerWaalsContact NE1-CD 3.32Å; W346-E372 PolarHBondContact NE1-OE2 3Å; V368-E372 PolarHBondContact O-N 3.38Å; L369-E372 WeakPolarHBondContact O-CB 3.48Å; L369-E372 PolarHBondContact O-N 2.8Å; L369-E372 VanDerWaalsContact O-N 3.1Å; L370-E372 VanDerWaalsContact C-N 3.31Å; L370-E372 PolarHBondContact O-N 3.15Å; E372-A375 CarbonylContact O-C 3.47Å; E372-A375 PolarHBondContact O-N 3.39Å; E372-Y376 PolarHBondContact O-N 3.24Å; E372-Y376 VanDerWaalsContact O-N 3.12Å; E372-G377 PolarHBondContact O-N 2.98Å; E372-P380 HydrophobicContact CG-CG 3.65Å
373I98.5Very high97.7Very high0 Ų028.7 Ų28.70%013%0.131CC..Hα-helixtrans-58.7-55.6178.4-70.6179.4000110.2L268 L272 L285 F288 L369 L370 W371 A375 Y376L268-I373 HydrophobicContact CD2-CD1 3.9Å; L268-I373 HydrophobicContact CD2-CG1 3.8Å; L272-I373 HydrophobicContact CD1-CG1 4.45Å; L285-I373 HydrophobicContact CB-CG2 3.77Å; L285-I373 HydrophobicContact CD2-CG2 3.74Å; L285-I373 HydrophobicContact CG-CG2 4.26Å; F288-I373 HydrophobicContact CB-CD1 4.28Å; L369-I373 HydrophobicContact CD2-CD1 3.44Å; L369-I373 VanDerWaalsContact CD2-CD1 3.44Å; L369-I373 HydrophobicContact CD2-CG1 4.06Å; L369-I373 WeakPolarHBondContact O-CG1 3.41Å; L369-I373 PolarHBondContact O-N 3.16Å; L370-I373 WeakPolarHBondContact O-CB 3.43Å; L370-I373 PolarHBondContact O-N 3.35Å; L370-I373 VanDerWaalsContact O-N 3.16Å; W371-I373 VanDerWaalsContact C-N 3.34Å; W371-I373 PolarHBondContact O-N 2.98Å; I373-A375 VanDerWaalsContact C-N 3.26Å; I373-A375 PolarHBondContact O-N 3.06Å; I373-Y376 PolarHBondContact O-N 3.37Å; I373-Y376 VanDerWaalsContact O-N 3.09Å
374F98.2Very high97.5Very high5 Ų530.2 Ų30.22%0.02214%0.138CC..Hα-helixtrans-73.3-18.6-177.1-75.5-85.1000113.3L285 L286 L370 W371 Y376 P402 C405 P406 A409 M413L285-F374 HydrophobicContact CB-CE1 4.1Å; L285-F374 HydrophobicContact CB-CZ 4.23Å; L285-F374 HydrophobicContact CD1-CD1 3.93Å; L285-F374 HydrophobicContact CD1-CE1 4.21Å; L286-F374 HydrophobicContact CD2-CZ 3.82Å; L286-F374 HydrophobicContact CG-CZ 4.06Å; L370-F374 VanDerWaalsContact O-CD2 3.31Å; L370-F374 WeakPolarHBondContact O-CD2 3.36Å; L370-F374 PolarHBondContact O-N 2.97Å; W371-F374 PolarHBondContact O-N 3.04Å; F374-Y376 VanDerWaalsContact C-N 3.34Å; F374-P402 HydrophobicContact CB-CB 4.28Å; F374-P402 HydrophobicContact CB-CG 4.02Å; F374-C405 HydrophobicContact CB-CB 4.4Å; F374-P406 HydrophobicContact CE1-CG 4.13Å; F374-A409 HydrophobicContact CD2-CB 4.36Å; F374-A409 HydrophobicContact CE1-CB 3.93Å; F374-A409 HydrophobicContact CE2-CB 3.77Å; F374-A409 HydrophobicContact CZ-CB 3.52Å; F374-M413 HydrophobicContact CB-CE 3.96Å; F374-M413 HydrophobicContact CD2-CE 3.51Å; F374-M413 HydrophobicContact CE2-CE 4.33Å; F374-M413 HydrophobicContact CG-CE 3.94Å
375A97.6Very high97.4Very high1 Ų132.9 Ų32.91%0.00816%0.157CC..THydrogen-bonded Turntrans-9210.4171.100000113.4W371 E372 I373 G377 R378 P402W371-A375 HydrophobicContact CD2-CB 4.2Å; W371-A375 HydrophobicContact CE3-CB 3.87Å; W371-A375 HydrophobicContact CH2-CB 3.92Å; W371-A375 HydrophobicContact CZ2-CB 4.24Å; W371-A375 HydrophobicContact CZ3-CB 3.72Å; W371-A375 WeakPolarHBondContact O-CB 3.3Å; W371-A375 PolarHBondContact O-N 2.99Å; E372-A375 CarbonylContact O-C 3.47Å; E372-A375 PolarHBondContact O-N 3.39Å; I373-A375 VanDerWaalsContact C-N 3.26Å; I373-A375 PolarHBondContact O-N 3.06Å; A375-G377 PolarHBondContact O-N 3.09Å; A375-R378 HydrophobicContact CB-CB 3.92Å; A375-R378 HydrophobicContact CB-CG 4.49Å; A375-R378 WeakPolarHBondContact O-CB 3.48Å; A375-R378 VanDerWaalsContact O-CG 3.23Å; A375-R378 WeakPolarHBondContact O-CG 3.41Å; A375-R378 PolarHBondContact O-N 3.23Å; A375-P402 HydrophobicContact CB-CB 4.05Å; A375-P402 HydrophobicContact CB-CG 4.15Å
376Y97.6Very high97.1Very high27 Ų2737.5 Ų37.511%0.10618%0.181CC..THydrogen-bonded Turntrans55.246.2178.7-67-99.3000113.5L272 R277 V280 L285 E372 I373 F374 R378L272-Y376 HydrophobicContact CD2-CD1 4.49Å; R277-Y376 VanDerWaalsContact CA-CE1 3.47Å; R277-Y376 HydrophobicContact CB-CE1 4.17Å; R277-Y376 HydrophobicContact CG-CD1 4.08Å; R277-Y376 HydrophobicContact CG-CD2 3.75Å; R277-Y376 HydrophobicContact CG-CE1 3.68Å; R277-Y376 HydrophobicContact CG-CE2 3.34Å; R277-Y376 HydrophobicContact CG-CG 4.1Å; V280-Y376 HydrophobicContact CB-CE1 4.2Å; V280-Y376 WeakPolarHBondContact O-CE1 3.24Å; V280-Y376 PolarHBondContact O-OH 2.75Å; L285-Y376 HydrophobicContact CD1-CE1 4.41Å; L285-Y376 HydrophobicContact CD1-CE2 3.96Å; L285-Y376 HydrophobicContact CD2-CE1 4.33Å; E372-Y376 PolarHBondContact O-N 3.24Å; E372-Y376 VanDerWaalsContact O-N 3.12Å; I373-Y376 PolarHBondContact O-N 3.37Å; I373-Y376 VanDerWaalsContact O-N 3.09Å; F374-Y376 VanDerWaalsContact C-N 3.34Å; Y376-R378 VanDerWaalsContact C-N 3.3Å; Y376-R378 PolarHBondContact O-N 3.24Å
377G96.4Very high96.8Very high0 Ų044.6 Ų44.60%021%0.212CC..THydrogen-bonded Turntrans74.414.117800000114.2R273 E372 A375R273-G377 PolarHBondContact NE-O 2.78Å; R273-G377 PolarHBondContact NH2-O 3.14Å; E372-G377 PolarHBondContact O-N 2.98Å; A375-G377 PolarHBondContact O-N 3.09Å
378R96.6Very high96.7Very high128 Ų12848.2 Ų48.248%0.48323%0.229SC..PPolyproline II helixtrans-57.8148.8168.6-76.9176.7-177.9173.76.5109.9W371 A375 Y376 E403W371-R378 HydrophobicContact CH2-CB 4.2Å; W371-R378 HydrophobicContact CZ3-CB 4.13Å; A375-R378 HydrophobicContact CB-CB 3.92Å; A375-R378 HydrophobicContact CB-CG 4.49Å; A375-R378 WeakPolarHBondContact O-CB 3.48Å; A375-R378 VanDerWaalsContact O-CG 3.23Å; A375-R378 WeakPolarHBondContact O-CG 3.41Å; A375-R378 PolarHBondContact O-N 3.23Å; Y376-R378 VanDerWaalsContact C-N 3.3Å; Y376-R378 PolarHBondContact O-N 3.24Å; R378-E403 IonicContact NH2-OE2 3.59Å
379Q95.8Very high96.5Very high116 Ų11648.4 Ų48.454%0.54223%0.23SC..PPolyproline II helixtrans-69.2132.5178.3-167.1-176.458.900110.3K345K345-Q379 VanDerWaalsContact NZ-OE1 3.11Å
380P97.8Very high96.2Very high1 Ų152.6 Ų52.61%0.00625%0.248CC..SBendtrans-57.1150.8175.1-27.936.7000112.7K345 W346 V368 W371 E372 M399K345-P380 HydrophobicContact CB-CB 4.45Å; K345-P380 WeakPolarHBondContact CD-O 3.27Å; K345-P380 WeakPolarHBondContact CE-O 3.4Å; K345-P380 PolarHBondContact NZ-O 2.94Å; W346-P380 HydrophobicContact CH2-CG 4.38Å; W346-P380 HydrophobicContact CZ2-CG 3.69Å; V368-P380 HydrophobicContact CG1-CB 3.81Å; V368-P380 HydrophobicContact CG1-CG 3.62Å; W371-P380 HydrophobicContact CE3-CB 4.48Å; W371-P380 HydrophobicContact CE3-CG 4.42Å; E372-P380 HydrophobicContact CG-CG 3.65Å; P380-M399 HydrophobicContact CB-CE 4.32Å; P380-M399 HydrophobicContact CB-SD 4.11Å
381Y97.3Very high96Very high2 Ų257.4 Ų57.41%0.00827%0.27CS..SBendtrans50.564.5-178.8-51.4-91.4000111.6K345 K383 M384 V389 V393 Y397 M399K345-Y381 HydrophobicContact CB-CD2 4.03Å; K345-Y381 HydrophobicContact CB-CE2 4.3Å; K345-Y381 HydrophobicContact CD-CD2 4.46Å; K345-Y381 HydrophobicContact CG-CD2 4.16Å; K345-Y381 PolarHBondContact NZ-O 3.35Å; K345-Y381 WeakPolarHBondContact O-CE2 3.47Å; Y381-K383 PolarHBondContact O-N 3.17Å; Y381-M384 HydrophobicContact CD1-SD 4.38Å; Y381-M384 PolarHBondContact O-N 2.86Å; Y381-V389 VanDerWaalsContact CB-CG2 3.47Å; Y381-V389 HydrophobicContact CD1-CG1 4.09Å; Y381-V389 HydrophobicContact CD1-CG2 4.12Å; Y381-V389 HydrophobicContact CD2-CG1 3.98Å; Y381-V389 HydrophobicContact CD2-CG2 4.22Å; Y381-V389 HydrophobicContact CE1-CG1 4.22Å; Y381-V389 HydrophobicContact CE2-CG1 4.14Å; Y381-V389 HydrophobicContact CG-CB 4.49Å; Y381-V389 HydrophobicContact CG-CG1 3.98Å; Y381-V389 HydrophobicContact CG-CG2 3.68Å; Y381-V393 HydrophobicContact CE1-CG2 3.63Å; Y381-Y397 HydrophobicContact CD1-CD1 4.45Å; Y381-Y397 AromaticContact CD1-CE1 3.89Å; Y381-Y397 HydrophobicContact CD1-CE1 3.89Å; Y381-Y397 HydrophobicContact CE1-CD1 4.31Å; Y381-Y397 HydrophobicContact CE1-CE1 4.02Å; Y381-M399 HydrophobicContact CD1-CG 3.7Å; Y381-M399 HydrophobicContact CD1-SD 4.01Å; Y381-M399 HydrophobicContact CD2-CE 4.49Å; Y381-M399 HydrophobicContact CD2-SD 3.89Å; Y381-M399 HydrophobicContact CE1-CG 3.59Å; Y381-M399 HydrophobicContact CE1-SD 4.06Å; Y381-M399 HydrophobicContact CE2-CE 3.95Å; Y381-M399 HydrophobicContact CE2-CG 4.5Å; Y381-M399 HydrophobicContact CE2-SD 3.9Å; Y381-M399 HydrophobicContact CG-CG 4.23Å; Y381-M399 HydrophobicContact CG-SD 3.92Å; Y381-M399 PolarHBondContact N-SD 3.43Å
382P94.6Very high95.8Very high74 Ų7460.9 Ų60.948%0.48129%0.286SS..THydrogen-bonded Turntrans-58.9140.6-177.225.9-34.5000110.3M384P382-M384 PolarHBondContact O-N 3.36Å
383K94Very high95.6Very high217 Ų21760.8 Ų60.894%0.94329%0.286SS*.THydrogen-bonded Turntrans62.417.1179-49.3176.3-178.6177.90115.3Y381Y381-K383 PolarHBondContact O-N 3.17Å
384M95.8Very high95.3Very high32 Ų3264.4 Ų64.416%0.15830%0.303CS..  trans-113.2134.1173.3-58.6-174.8-174.700111.1Y381 P382 E388 V389 K392 Y397Y381-M384 HydrophobicContact CD1-SD 4.38Å; Y381-M384 PolarHBondContact O-N 2.86Å; P382-M384 PolarHBondContact O-N 3.36Å; M384-E388 HydrophobicContact CB-CB 4.38Å; M384-V389 HydrophobicContact CB-CG2 3.72Å; M384-K392 HydrophobicContact CE-CD 4.08Å; M384-K392 HydrophobicContact SD-CD 3.96Å; M384-Y397 HydrophobicContact CE-CE1 3.98Å; M384-Y397 HydrophobicContact CE-CE2 4.35Å; M384-Y397 HydrophobicContact SD-CE1 4.31Å
385S95.3Very high95.1Very high58 Ų5868.4 Ų68.441%0.40634%0.336SS..  trans-69.1161.2168.768.50000111.4K387 E388 V389S385-K387 PolarHBondContact O-N 3.2Å; S385-E388 VanDerWaalsContact CB-OE2 3.27Å; S385-E388 WeakPolarHBondContact CB-OE2 3.41Å; S385-E388 PolarHBondContact N-OE2 3.11Å; S385-E388 PolarHBondContact O-N 3.36Å; S385-E388 VanDerWaalsContact OG-CG 3.28Å; S385-E388 WeakPolarHBondContact OG-CG 3.07Å; S385-E388 PolarHBondContact OG-N 3.15Å; S385-E388 PolarHBondContact OG-OE2 2.92Å; S385-V389 WeakPolarHBondContact O-CG2 3.21Å; S385-V389 PolarHBondContact O-N 3.31Å
386L92.6Very high95Very high101 Ų10170.3 Ų70.353%0.52936%0.357SS..Hα-helixtrans-59.7-34.6179.3-58.7-177.6000112.6V344 K345 K390V344-L386 HydrophobicContact CB-CD2 4.31Å; V344-L386 HydrophobicContact CG1-CB 4.46Å; K345-L386 HydrophobicContact CD-CD2 4.36Å; K345-L386 HydrophobicContact CG-CD2 3.95Å; L386-K390 PolarHBondContact O-N 3.43Å
387K92.9Very high94.9Very high149 Ų14972.6 Ų72.665%0.64837%0.365SS*.Hα-helixtrans-65.4-49.6176.5-177.3179.9172-175.50111S385 V389 K390 E391S385-K387 PolarHBondContact O-N 3.2Å; K387-V389 VanDerWaalsContact C-N 3.32Å; K387-V389 PolarHBondContact O-N 2.7Å; K387-K390 PolarHBondContact O-N 2.85Å; K387-E391 WeakPolarHBondContact CE-OE1 3.5Å; K387-E391 IonicContact NZ-OE1 3.84Å; K387-E391 WeakPolarHBondContact O-CG 3.2Å; K387-E391 PolarHBondContact O-N 3.1Å
388E95.9Very high95Very high77 Ų7774.9 Ų74.936%0.3637%0.374SS..Hα-helixtrans-62.7-39178.5-70.4166.8117.400112.2M384 S385 K390 E391 K392M384-E388 HydrophobicContact CB-CB 4.38Å; S385-E388 VanDerWaalsContact CB-OE2 3.27Å; S385-E388 WeakPolarHBondContact CB-OE2 3.41Å; S385-E388 PolarHBondContact N-OE2 3.11Å; S385-E388 PolarHBondContact O-N 3.36Å; S385-E388 VanDerWaalsContact OG-CG 3.28Å; S385-E388 WeakPolarHBondContact OG-CG 3.07Å; S385-E388 PolarHBondContact OG-N 3.15Å; S385-E388 PolarHBondContact OG-OE2 2.92Å; E388-K390 VanDerWaalsContact C-N 3.35Å; E388-K390 PolarHBondContact O-N 3.41Å; E388-E391 PolarHBondContact O-N 3.18Å; E388-K392 VanDerWaalsContact O-CB 3.3Å; E388-K392 WeakPolarHBondContact O-CB 3.46Å; E388-K392 WeakPolarHBondContact O-CG 3.43Å; E388-K392 PolarHBondContact O-N 3.06Å
389V94.8Very high95Very high3 Ų368.9 Ų68.92%0.01835%0.351CS..Hα-helixtrans-58.4-49.5175.7171.30000110.1K345 Y381 M384 S385 K387 E391 V393K345-V389 HydrophobicContact CG-CG2 4.45Å; Y381-V389 VanDerWaalsContact CB-CG2 3.47Å; Y381-V389 HydrophobicContact CD1-CG1 4.09Å; Y381-V389 HydrophobicContact CD1-CG2 4.12Å; Y381-V389 HydrophobicContact CD2-CG1 3.98Å; Y381-V389 HydrophobicContact CD2-CG2 4.22Å; Y381-V389 HydrophobicContact CE1-CG1 4.22Å; Y381-V389 HydrophobicContact CE2-CG1 4.14Å; Y381-V389 HydrophobicContact CG-CB 4.49Å; Y381-V389 HydrophobicContact CG-CG1 3.98Å; Y381-V389 HydrophobicContact CG-CG2 3.68Å; M384-V389 HydrophobicContact CB-CG2 3.72Å; S385-V389 WeakPolarHBondContact O-CG2 3.21Å; S385-V389 PolarHBondContact O-N 3.31Å; K387-V389 VanDerWaalsContact C-N 3.32Å; K387-V389 PolarHBondContact O-N 2.7Å; V389-E391 PolarHBondContact O-N 3.47Å; V389-V393 HydrophobicContact CG1-CG2 4.19Å; V389-V393 WeakPolarHBondContact O-CB 3.49Å; V389-V393 WeakPolarHBondContact O-CG2 3.33Å; V389-V393 PolarHBondContact O-N 3.29Å
390K92.2Very high95.1Very high88 Ų8870.7 Ų70.738%0.38336%0.36SS..Hα-helixtrans-57.6-51.7178.7-175.8-179.2178.6-179.30111.3L352 L386 K387 E388 E394L352-K390 HydrophobicContact CD1-CG 4.45Å; L386-K390 PolarHBondContact O-N 3.43Å; K387-K390 PolarHBondContact O-N 2.85Å; E388-K390 VanDerWaalsContact C-N 3.35Å; E388-K390 PolarHBondContact O-N 3.41Å; K390-E394 VanDerWaalsContact CE-OE1 3.31Å; K390-E394 WeakPolarHBondContact CE-OE1 3.17Å; K390-E394 WeakPolarHBondContact O-CB 3.48Å; K390-E394 VanDerWaalsContact O-CG 3.27Å; K390-E394 WeakPolarHBondContact O-CG 3.36Å; K390-E394 PolarHBondContact O-N 3.29Å; K390-E394 VanDerWaalsContact O-N 3.09Å
391E94Very high95.1Very high103 Ų10373 Ų7348%0.48138%0.379SS..Hα-helixtrans-63.1-46.7-177.3-70.3170.3175.700112.3K387 E388 V389 E394 A395K387-E391 WeakPolarHBondContact CE-OE1 3.5Å; K387-E391 IonicContact NZ-OE1 3.84Å; K387-E391 WeakPolarHBondContact O-CG 3.2Å; K387-E391 PolarHBondContact O-N 3.1Å; E388-E391 PolarHBondContact O-N 3.18Å; V389-E391 PolarHBondContact O-N 3.47Å; E391-E394 PolarHBondContact O-N 3.12Å; E391-A395 WeakPolarHBondContact O-CB 3.5Å; E391-A395 PolarHBondContact O-N 3.18Å
392K95.7Very high95.1Very high90 Ų9073.4 Ų73.439%0.39138%0.382SS..Hα-helixtrans-68.8-43.7-178.3-73.5-175.8175.1179.30112.4M384 E388 E394 A395 G396 Y397M384-K392 HydrophobicContact CE-CD 4.08Å; M384-K392 HydrophobicContact SD-CD 3.96Å; E388-K392 VanDerWaalsContact O-CB 3.3Å; E388-K392 WeakPolarHBondContact O-CB 3.46Å; E388-K392 WeakPolarHBondContact O-CG 3.43Å; E388-K392 PolarHBondContact O-N 3.06Å; K392-E394 VanDerWaalsContact C-N 3.31Å; K392-E394 PolarHBondContact O-N 3.29Å; K392-A395 CarbonylContact O-C 3.54Å; K392-A395 WeakPolarHBondContact O-CA 3.39Å; K392-A395 WeakPolarHBondContact O-CB 3.43Å; K392-A395 PolarHBondContact O-N 2.99Å; K392-A395 VanDerWaalsContact O-N 3.11Å; K392-G396 PolarHBondContact O-N 3.27Å; K392-Y397 HydrophobicContact CB-CD1 4.28Å; K392-Y397 HydrophobicContact CB-CG 4.2Å; K392-Y397 WeakPolarHBondContact O-CB 3.35Å; K392-Y397 PolarHBondContact O-N 3Å
393V95.1Very high95Very high4 Ų475.2 Ų75.22%0.02438%0.384CS..Hα-helixtrans-62.9-40.8179165.20000110.8P349 W364 Y381 V389 A395 G396 R398P349-V393 HydrophobicContact CG-CG1 3.77Å; W364-V393 HydrophobicContact CH2-CG1 3.62Å; W364-V393 HydrophobicContact CZ2-CG1 3.47Å; W364-V393 VanDerWaalsContact CZ2-CG1 3.47Å; Y381-V393 HydrophobicContact CE1-CG2 3.63Å; V389-V393 HydrophobicContact CG1-CG2 4.19Å; V389-V393 WeakPolarHBondContact O-CB 3.49Å; V389-V393 WeakPolarHBondContact O-CG2 3.33Å; V389-V393 PolarHBondContact O-N 3.29Å; V393-A395 VanDerWaalsContact C-N 3.29Å; V393-A395 PolarHBondContact O-N 2.9Å; V393-G396 PolarHBondContact O-N 2.83Å; V393-G396 VanDerWaalsContact O-N 3.1Å; V393-R398 PolarHBondContact O-NH1 3.14Å; V393-R398 VanDerWaalsContact O-NH1 3.11Å
394E91.3Very high94.8Very high77 Ų7771.2 Ų71.236%0.3637%0.373SS..Hα-helixtrans-62.4-35.3173.1-76-179.3-172.400112.3K390 E391 K392 G396K390-E394 VanDerWaalsContact CE-OE1 3.31Å; K390-E394 WeakPolarHBondContact CE-OE1 3.17Å; K390-E394 WeakPolarHBondContact O-CB 3.48Å; K390-E394 VanDerWaalsContact O-CG 3.27Å; K390-E394 WeakPolarHBondContact O-CG 3.36Å; K390-E394 PolarHBondContact O-N 3.29Å; K390-E394 VanDerWaalsContact O-N 3.09Å; E391-E394 PolarHBondContact O-N 3.12Å; K392-E394 VanDerWaalsContact C-N 3.31Å; K392-E394 PolarHBondContact O-N 3.29Å; E394-G396 PolarHBondContact O-N 3.04Å
395A94.3Very high94.7Very high88 Ų8870.6 Ų70.673%0.72737%0.371SS*.THydrogen-bonded Turntrans-76.92.2174.200000114.4E391 K392 V393E391-A395 WeakPolarHBondContact O-CB 3.5Å; E391-A395 PolarHBondContact O-N 3.18Å; K392-A395 CarbonylContact O-C 3.54Å; K392-A395 WeakPolarHBondContact O-CA 3.39Å; K392-A395 WeakPolarHBondContact O-CB 3.43Å; K392-A395 PolarHBondContact O-N 2.99Å; K392-A395 VanDerWaalsContact O-N 3.11Å; V393-A395 VanDerWaalsContact C-N 3.29Å; V393-A395 PolarHBondContact O-N 2.9Å
396G94.5Very high94.7Very high42 Ų4269.3 Ų69.343%0.43336%0.362SS..THydrogen-bonded Turntrans97.31.9175.700000115.4K392 V393 E394 R398K392-G396 PolarHBondContact O-N 3.27Å; V393-G396 PolarHBondContact O-N 2.83Å; V393-G396 VanDerWaalsContact O-N 3.1Å; E394-G396 PolarHBondContact O-N 3.04Å; G396-R398 PolarHBondContact O-NH1 2.89Å
397Y96.9Very high94.8Very high75 Ų7570 Ų7029%0.29437%0.372SS..  trans-61141174.3172-97.2000111.6Y381 M384 K392 M399Y381-Y397 HydrophobicContact CD1-CD1 4.45Å; Y381-Y397 AromaticContact CD1-CE1 3.89Å; Y381-Y397 HydrophobicContact CD1-CE1 3.89Å; Y381-Y397 HydrophobicContact CE1-CD1 4.31Å; Y381-Y397 HydrophobicContact CE1-CE1 4.02Å; M384-Y397 HydrophobicContact CE-CE1 3.98Å; M384-Y397 HydrophobicContact CE-CE2 4.35Å; M384-Y397 HydrophobicContact SD-CE1 4.31Å; K392-Y397 HydrophobicContact CB-CD1 4.28Å; K392-Y397 HydrophobicContact CB-CG 4.2Å; K392-Y397 WeakPolarHBondContact O-CB 3.35Å; K392-Y397 PolarHBondContact O-N 3Å; Y397-M399 HydrophobicContact CE1-CG 4.31Å
398R97.5Very high95Very high47 Ų4763.7 Ų63.718%0.17735%0.35CS..  trans-132.1146.5171.5-59.9-60.1180-96.71.1109.5W364 V393 G396 W417W364-R398 VanDerWaalsContact CH2-CZ 3.48Å; V393-R398 PolarHBondContact O-NH1 3.14Å; V393-R398 VanDerWaalsContact O-NH1 3.11Å; G396-R398 PolarHBondContact O-NH1 2.89Å; R398-W417 HydrophobicContact CB-CE3 4.21Å; R398-W417 VanDerWaalsContact CD-CB 3.49Å; R398-W417 HydrophobicContact CG-CB 4.45Å; R398-W417 VanDerWaalsContact CZ-O 3.26Å; R398-W417 PolarHBondContact NE-O 3.13Å; R398-W417 PolarHBondContact NH2-O 3.06Å
399M97.9Very high95.1Very high2 Ų260.1 Ų60.11%0.0133%0.334CS..PPolyproline II helixtrans-62.2142.6179.4-67.5-175.1-70.700111V368 W371 P380 Y381 Y397 Y410 W417V368-M399 HydrophobicContact CG1-CE 4.28Å; W371-M399 HydrophobicContact CB-CE 3.87Å; W371-M399 HydrophobicContact CD2-CE 3.94Å; W371-M399 HydrophobicContact CD2-SD 3.88Å; W371-M399 HydrophobicContact CE3-CE 4.46Å; W371-M399 HydrophobicContact CE3-SD 4.3Å; W371-M399 HydrophobicContact CG-CE 3.65Å; W371-M399 HydrophobicContact CG-SD 4.15Å; W371-M399 HydrophobicContact CZ2-SD 4.37Å; P380-M399 HydrophobicContact CB-CE 4.32Å; P380-M399 HydrophobicContact CB-SD 4.11Å; Y381-M399 HydrophobicContact CD1-CG 3.7Å; Y381-M399 HydrophobicContact CD1-SD 4.01Å; Y381-M399 HydrophobicContact CD2-CE 4.49Å; Y381-M399 HydrophobicContact CD2-SD 3.89Å; Y381-M399 HydrophobicContact CE1-CG 3.59Å; Y381-M399 HydrophobicContact CE1-SD 4.06Å; Y381-M399 HydrophobicContact CE2-CE 3.95Å; Y381-M399 HydrophobicContact CE2-CG 4.5Å; Y381-M399 HydrophobicContact CE2-SD 3.9Å; Y381-M399 HydrophobicContact CG-CG 4.23Å; Y381-M399 HydrophobicContact CG-SD 3.92Å; Y381-M399 PolarHBondContact N-SD 3.43Å; Y397-M399 HydrophobicContact CE1-CG 4.31Å; M399-Y410 WeakPolarHBondContact O-CE2 3.29Å; M399-Y410 PolarHBondContact O-OH 3.16Å; M399-W417 HydrophobicContact CB-CH2 4.18Å; M399-W417 HydrophobicContact CB-CZ3 4.39Å; M399-W417 HydrophobicContact CE-CH2 3.81Å; M399-W417 HydrophobicContact CE-CZ2 3.6Å
400E97.4Very high95.3Very high154 Ų15462.2 Ų62.272%0.7234%0.341SS*.PPolyproline II helixtrans-64.1158.3170.6-64.3178.7175.200111.1W371W371-E400 PolarHBondContact NE1-O 3.3Å
401A97.6Very high95.6Very high49 Ų4960.1 Ų60.141%0.40534%0.341SS..PPolyproline II helixtrans-59.8133.7175.300000109.9Y410A401-Y410 HydrophobicContact CB-CD1 3.86Å; A401-Y410 HydrophobicContact CB-CD2 3.73Å; A401-Y410 HydrophobicContact CB-CE1 4.08Å; A401-Y410 HydrophobicContact CB-CE2 3.96Å; A401-Y410 HydrophobicContact CB-CG 3.67Å
402P96.3Very high95.8Very high12 Ų1255.5 Ų55.58%0.07832%0.319CS..PPolyproline II helixtrans-56.9152.2168.8-22.632.4000111.4W371 F374 A375 D404 C405W371-P402 HydrophobicContact CD2-CG 4.32Å; W371-P402 HydrophobicContact CG-CG 4.06Å; F374-P402 HydrophobicContact CB-CB 4.28Å; F374-P402 HydrophobicContact CB-CG 4.02Å; A375-P402 HydrophobicContact CB-CB 4.05Å; A375-P402 HydrophobicContact CB-CG 4.15Å; P402-D404 PolarHBondContact O-N 3.32Å; P402-C405 HydrophobicContact CB-CB 4.08Å; P402-C405 HydrophobicContact CG-CB 4.31Å; P402-C405 WeakPolarHBondContact O-CB 3.47Å; P402-C405 PolarHBondContact O-N 3.11Å
403E92.3Very high95.9Very high111 Ų11151.2 Ų51.252%0.51930%0.3SS..THydrogen-bonded Turntrans-53.1132.1171.4-171.2176.6-165.500110.7R378 C405R378-E403 IonicContact NH2-OE2 3.59Å; E403-C405 PolarHBondContact O-N 3.48Å
404D89.9Confident96.1Very high134 Ų13456.1 Ų56.172%0.71732%0.321SS*.THydrogen-bonded Turntrans59.416.7-176-49.9-44.1000115.6P402 P406P402-D404 PolarHBondContact O-N 3.32Å; D404-P406 WeakPolarHBondContact O-CD 3.24Å
405C94.8Very high96.4Very high18 Ų1855.1 Ų55.112%0.12232%0.319CS..  trans-70.1126175.9-174.60000111F374 P402 E403F374-C405 HydrophobicContact CB-CB 4.4Å; P402-C405 HydrophobicContact CB-CB 4.08Å; P402-C405 HydrophobicContact CG-CB 4.31Å; P402-C405 WeakPolarHBondContact O-CB 3.47Å; P402-C405 PolarHBondContact O-N 3.11Å; E403-C405 PolarHBondContact O-N 3.48Å
406P94.4Very high96.6Very high32 Ų3251 Ų5121%0.20828%0.284CS..  trans-57.1135.6174.5-25.735.2000111.7F374 D404 G408 A409 Y410F374-P406 HydrophobicContact CE1-CG 4.13Å; D404-P406 WeakPolarHBondContact O-CD 3.24Å; P406-G408 PolarHBondContact O-N 3.22Å; P406-G408 VanDerWaalsContact O-N 3.14Å; P406-A409 HydrophobicContact CB-CB 4.29Å; P406-A409 WeakPolarHBondContact O-CB 3.5Å; P406-A409 PolarHBondContact O-N 3.12Å; P406-Y410 PolarHBondContact O-N 3.4Å; P406-Y410 VanDerWaalsContact O-N 3.11Å
407P95.9Very high96.8Very high115 Ų11549.1 Ų49.175%0.74726%0.264SS*.Hα-helixtrans-55.7-35.8-178-28.935.3000114Y410 A411P407-Y410 PolarHBondContact O-N 3.02Å; P407-A411 WeakPolarHBondContact O-CB 3.21Å; P407-A411 PolarHBondContact O-N 3.17Å
408G96.8Very high96.9Very high17 Ų1749.1 Ų49.118%0.17527%0.267CS..Hα-helixtrans-66.2-40176.600000113.1P406 A411 I412 E437P406-G408 PolarHBondContact O-N 3.22Å; P406-G408 VanDerWaalsContact O-N 3.14Å; G408-A411 WeakPolarHBondContact O-CB 3.35Å; G408-A411 PolarHBondContact O-N 3.2Å; G408-I412 WeakPolarHBondContact O-CG1 3.49Å; G408-I412 PolarHBondContact O-N 2.68Å; G408-I412 VanDerWaalsContact O-N 3.11Å; G408-E437 WeakPolarHBondContact CA-OE2 3.37Å
409A97.3Very high96.8Very high2 Ų250.7 Ų50.72%0.01728%0.276CS..Hα-helixtrans-63.5-44.2174.200000111.5F374 P406 A411 I412 M413F374-A409 HydrophobicContact CD2-CB 4.36Å; F374-A409 HydrophobicContact CE1-CB 3.93Å; F374-A409 HydrophobicContact CE2-CB 3.77Å; F374-A409 HydrophobicContact CZ-CB 3.52Å; P406-A409 HydrophobicContact CB-CB 4.29Å; P406-A409 WeakPolarHBondContact O-CB 3.5Å; P406-A409 PolarHBondContact O-N 3.12Å; A409-A411 VanDerWaalsContact C-N 3.35Å; A409-A411 PolarHBondContact O-N 3.06Å; A409-I412 WeakPolarHBondContact O-CB 3.43Å; A409-I412 PolarHBondContact O-N 3.44Å; A409-M413 WeakPolarHBondContact O-CG 3.25Å; A409-M413 PolarHBondContact O-N 3.14Å; A409-M413 VanDerWaalsContact O-N 3.12Å
410Y98.5Very high96.7Very high46 Ų4655.4 Ų55.418%0.1830%0.298CS..Hα-helixtrans-66.7-35.3176.1-174.9-118.7000112.8M399 A401 P406 P407 I412 M413 K414 W417M399-Y410 WeakPolarHBondContact O-CE2 3.29Å; M399-Y410 PolarHBondContact O-OH 3.16Å; A401-Y410 HydrophobicContact CB-CD1 3.86Å; A401-Y410 HydrophobicContact CB-CD2 3.73Å; A401-Y410 HydrophobicContact CB-CE1 4.08Å; A401-Y410 HydrophobicContact CB-CE2 3.96Å; A401-Y410 HydrophobicContact CB-CG 3.67Å; P406-Y410 PolarHBondContact O-N 3.4Å; P406-Y410 VanDerWaalsContact O-N 3.11Å; P407-Y410 PolarHBondContact O-N 3.02Å; Y410-I412 VanDerWaalsContact C-N 3.27Å; Y410-I412 PolarHBondContact O-N 3.1Å; Y410-M413 HydrophobicContact CD2-CB 4.37Å; Y410-M413 HydrophobicContact CD2-SD 3.87Å; Y410-M413 WeakPolarHBondContact O-CB 3.35Å; Y410-M413 PolarHBondContact O-N 3.49Å; Y410-K414 HydrophobicContact CD1-CD 4.28Å; Y410-K414 HydrophobicContact CD1-CG 4.49Å; Y410-K414 HydrophobicContact CE1-CD 3.75Å; Y410-K414 HydrophobicContact CE1-CG 4.09Å; Y410-K414 HydrophobicContact CE2-CG 4.49Å; Y410-K414 PolarHBondContact O-N 3.15Å; Y410-W417 HydrophobicContact CE2-CZ3 4.19Å
411A98.4Very high96.6Very high45 Ų4550 Ų5037%0.37228%0.276SS..Hα-helixtrans-60-39.4173.200000111.7P407 G408 A409 K414 L415P407-A411 WeakPolarHBondContact O-CB 3.21Å; P407-A411 PolarHBondContact O-N 3.17Å; G408-A411 WeakPolarHBondContact O-CB 3.35Å; G408-A411 PolarHBondContact O-N 3.2Å; A409-A411 VanDerWaalsContact C-N 3.35Å; A409-A411 PolarHBondContact O-N 3.06Å; A411-K414 PolarHBondContact O-N 3.16Å; A411-L415 WeakPolarHBondContact O-CG 3.45Å; A411-L415 PolarHBondContact O-N 3.22Å; A411-L415 VanDerWaalsContact O-N 3.14Å
412I98.6Very high96.6Very high5 Ų558.9 Ų58.93%0.02630%0.299CS..Hα-helixtrans-63-44.2173.7-64.6165.8000110.9L370 G408 A409 Y410 K414 L415 C416 L430 K433 L434 E437L370-I412 HydrophobicContact CD1-CG2 3.78Å; G408-I412 WeakPolarHBondContact O-CG1 3.49Å; G408-I412 PolarHBondContact O-N 2.68Å; G408-I412 VanDerWaalsContact O-N 3.11Å; A409-I412 WeakPolarHBondContact O-CB 3.43Å; A409-I412 PolarHBondContact O-N 3.44Å; Y410-I412 VanDerWaalsContact C-N 3.27Å; Y410-I412 PolarHBondContact O-N 3.1Å; I412-K414 VanDerWaalsContact C-N 3.31Å; I412-K414 PolarHBondContact O-N 2.81Å; I412-L415 WeakPolarHBondContact O-CB 3.28Å; I412-L415 PolarHBondContact O-N 3.11Å; I412-L415 VanDerWaalsContact O-N 3.16Å; I412-C416 PolarHBondContact O-N 3.37Å; I412-C416 VanDerWaalsContact O-N 3.09Å; I412-C416 PolarHBondContact O-SG 2.92Å; I412-C416 VanDerWaalsContact O-SG 3.39Å; I412-L430 HydrophobicContact CG2-CD2 3.64Å; I412-K433 HydrophobicContact CD1-CB 3.85Å; I412-K433 HydrophobicContact CG1-CB 4.07Å; I412-K433 HydrophobicContact CG1-CD 4.41Å; I412-L434 HydrophobicContact CD1-CD2 3.82Å; I412-L434 HydrophobicContact CD1-CG 4.04Å; I412-E437 HydrophobicContact CD1-CG 4.17Å
413M98.7Very high96.6Very high0 Ų064 Ų640%032%0.32CS..Hα-helixtrans-57-43.8175.7-61.3174.9-161.300111.9L370 W371 F374 A409 Y410 L415 C416 W417L370-M413 HydrophobicContact CB-CE 3.96Å; L370-M413 HydrophobicContact CB-CG 3.76Å; L370-M413 HydrophobicContact CB-SD 4.42Å; L370-M413 HydrophobicContact CD1-CG 4.14Å; W371-M413 HydrophobicContact CB-SD 4.08Å; F374-M413 HydrophobicContact CB-CE 3.96Å; F374-M413 HydrophobicContact CD2-CE 3.51Å; F374-M413 HydrophobicContact CE2-CE 4.33Å; F374-M413 HydrophobicContact CG-CE 3.94Å; A409-M413 WeakPolarHBondContact O-CG 3.25Å; A409-M413 PolarHBondContact O-N 3.14Å; A409-M413 VanDerWaalsContact O-N 3.12Å; Y410-M413 HydrophobicContact CD2-CB 4.37Å; Y410-M413 HydrophobicContact CD2-SD 3.87Å; Y410-M413 WeakPolarHBondContact O-CB 3.35Å; Y410-M413 PolarHBondContact O-N 3.49Å; M413-L415 PolarHBondContact O-N 3.39Å; M413-C416 WeakPolarHBondContact O-CB 3.43Å; M413-C416 PolarHBondContact O-N 3.09Å; M413-C416 VanDerWaalsContact O-N 3.14Å; M413-W417 HydrophobicContact CB-CE3 4.21Å; M413-W417 HydrophobicContact CB-CH2 3.81Å; M413-W417 HydrophobicContact CB-CZ2 4.19Å; M413-W417 HydrophobicContact CB-CZ3 3.82Å; M413-W417 HydrophobicContact CG-CH2 4.41Å; M413-W417 VanDerWaalsContact O-CD2 3.29Å; M413-W417 PolarHBondContact O-N 3.43Å; M413-W417 VanDerWaalsContact O-N 3.1Å; M413-W417 HydrophobicContact SD-CH2 4.19Å
414K98.6Very high96.9Very high107 Ų10758.8 Ų58.847%0.46530%0.296SS..Hα-helixtrans-62.5-39.3177.5-70.2-169.5-64.6-1800112.8Y410 A411 I412 C416 W417 E418Y410-K414 HydrophobicContact CD1-CD 4.28Å; Y410-K414 HydrophobicContact CD1-CG 4.49Å; Y410-K414 HydrophobicContact CE1-CD 3.75Å; Y410-K414 HydrophobicContact CE1-CG 4.09Å; Y410-K414 HydrophobicContact CE2-CG 4.49Å; Y410-K414 PolarHBondContact O-N 3.15Å; A411-K414 PolarHBondContact O-N 3.16Å; I412-K414 VanDerWaalsContact C-N 3.31Å; I412-K414 PolarHBondContact O-N 2.81Å; K414-C416 VanDerWaalsContact C-N 3.29Å; K414-C416 PolarHBondContact O-N 3.4Å; K414-W417 CarbonylContact O-C 3.53Å; K414-W417 PolarHBondContact O-N 2.69Å; K414-W417 VanDerWaalsContact O-N 3.13Å; K414-E418 PolarHBondContact O-N 3.25Å
415L98.5Very high97.3Very high57 Ų5753.5 Ų53.530%0.29827%0.269SS..Hα-helixtrans-61.4-38.5173.8-67.3173.1000111.9A411 I412 M413 W417 P425 K433A411-L415 WeakPolarHBondContact O-CG 3.45Å; A411-L415 PolarHBondContact O-N 3.22Å; A411-L415 VanDerWaalsContact O-N 3.14Å; I412-L415 WeakPolarHBondContact O-CB 3.28Å; I412-L415 PolarHBondContact O-N 3.11Å; I412-L415 VanDerWaalsContact O-N 3.16Å; M413-L415 PolarHBondContact O-N 3.39Å; L415-W417 VanDerWaalsContact C-N 3.27Å; L415-W417 PolarHBondContact O-N 3.5Å; L415-P425 HydrophobicContact CB-CG 4.18Å; L415-K433 HydrophobicContact CD1-CD 3.89Å
416C98.8Very high97.5Very high0 Ų053.6 Ų53.60%027%0.272CS..Hα-helixtrans-65.4-31.3175.6-66.80000112.5V363 I412 M413 K414 R424V363-C416 HydrophobicContact CG1-CB 4.12Å; V363-C416 VanDerWaalsContact O-CB 3.29Å; V363-C416 WeakPolarHBondContact O-CB 3.36Å; I412-C416 PolarHBondContact O-N 3.37Å; I412-C416 VanDerWaalsContact O-N 3.09Å; I412-C416 PolarHBondContact O-SG 2.92Å; I412-C416 VanDerWaalsContact O-SG 3.39Å; M413-C416 WeakPolarHBondContact O-CB 3.43Å; M413-C416 PolarHBondContact O-N 3.09Å; M413-C416 VanDerWaalsContact O-N 3.14Å; K414-C416 VanDerWaalsContact C-N 3.29Å; K414-C416 PolarHBondContact O-N 3.4Å; C416-R424 VanDerWaalsContact O-CD 3.25Å; C416-R424 WeakPolarHBondContact O-CD 3.44Å
417W98.5Very high97.7Very high4 Ų452.1 Ų52.12%0.01526%0.263CS..THydrogen-bonded Turntrans-96.721.2-177.5-53.8-40000114.7W364 G367 V368 W371 R398 M399 Y410 M413 K414 L415 Q419W364-W417 AromaticContact CD2-CD1 3.83Å; W364-W417 AromaticContact CE2-CD1 3.94Å; W364-W417 HydrophobicContact CE3-CB 4.16Å; W364-W417 HydrophobicContact CH2-CB 4.19Å; W364-W417 HydrophobicContact CZ3-CB 3.9Å; W364-W417 WeakPolarHBondContact CZ3-O 3.27Å; W364-W417 PolarHBondContact O-NE1 3.35Å; G367-W417 VanDerWaalsContact C-CZ2 3.47Å; G367-W417 WeakPolarHBondContact O-CZ2 3.41Å; V368-W417 HydrophobicContact CG2-CZ2 4.46Å; W371-W417 HydrophobicContact CB-CH2 4.08Å; W371-W417 HydrophobicContact CB-CZ2 4.11Å; W371-W417 HydrophobicContact CG-CH2 4.34Å; R398-W417 HydrophobicContact CB-CE3 4.21Å; R398-W417 VanDerWaalsContact CD-CB 3.49Å; R398-W417 HydrophobicContact CG-CB 4.45Å; R398-W417 VanDerWaalsContact CZ-O 3.26Å; R398-W417 PolarHBondContact NE-O 3.13Å; R398-W417 PolarHBondContact NH2-O 3.06Å; M399-W417 HydrophobicContact CB-CH2 4.18Å; M399-W417 HydrophobicContact CB-CZ3 4.39Å; M399-W417 HydrophobicContact CE-CH2 3.81Å; M399-W417 HydrophobicContact CE-CZ2 3.6Å; Y410-W417 HydrophobicContact CE2-CZ3 4.19Å; M413-W417 HydrophobicContact CB-CE3 4.21Å; M413-W417 HydrophobicContact CB-CH2 3.81Å; M413-W417 HydrophobicContact CB-CZ2 4.19Å; M413-W417 HydrophobicContact CB-CZ3 3.82Å; M413-W417 HydrophobicContact CG-CH2 4.41Å; M413-W417 VanDerWaalsContact O-CD2 3.29Å; M413-W417 PolarHBondContact O-N 3.43Å; M413-W417 VanDerWaalsContact O-N 3.1Å; M413-W417 HydrophobicContact SD-CH2 4.19Å; K414-W417 CarbonylContact O-C 3.53Å; K414-W417 PolarHBondContact O-N 2.69Å; K414-W417 VanDerWaalsContact O-N 3.13Å; L415-W417 VanDerWaalsContact C-N 3.27Å; L415-W417 PolarHBondContact O-N 3.5Å; W417-Q419 PolarHBondContact O-N 2.79Å
418E98.3Very high97.8Very high75 Ų7548.9 Ų48.935%0.3524%0.243SC..  trans-54.6133.6168.2-78-65156.100110.8K414 E420 K423 R424K414-E418 PolarHBondContact O-N 3.25Å; E418-E420 VanDerWaalsContact C-N 3.33Å; E418-E420 PolarHBondContact O-N 3.21Å; E418-K423 HydrophobicContact CB-CB 3.91Å; E418-K423 HydrophobicContact CG-CB 4.03Å; E418-R424 HydrophobicContact CB-CG 3.85Å; E418-R424 PolarHBondContact O-NE 2.77Å; E418-R424 PolarHBondContact O-NH2 3.31Å
419Q95.4Very high97.9Very high79 Ų7952.9 Ų52.937%0.36926%0.255SS..SBendtrans-63-42.2-175.1-174.164.333.400111.1W417 P421W417-Q419 PolarHBondContact O-N 2.79Å; Q419-P421 WeakPolarHBondContact O-CD 3.22Å
420E95.4Very high97.9Very high102 Ų10252.8 Ų52.848%0.47725%0.254SS..SBendtrans-84.4120.6176.6-68.7175.9-113.400110.2E418 R422 K423E418-E420 VanDerWaalsContact C-N 3.33Å; E418-E420 PolarHBondContact O-N 3.21Å; E420-R422 PolarHBondContact O-N 2.7Å; E420-K423 HydrophobicContact CB-CB 4.46Å; E420-K423 HydrophobicContact CB-CD 4.07Å; E420-K423 HydrophobicContact CB-CG 4.09Å; E420-K423 WeakPolarHBondContact O-CB 3.19Å; E420-K423 PolarHBondContact O-N 3.22Å; E420-K423 WeakPolarHBondContact OE1-CE 3.31Å; E420-K423 IonicContact OE1-NZ 3.29Å; E420-K423 PolarHBondContact OE1-NZ 2.96Å
421P96.4Very high97.9Very high39 Ų3953.7 Ų53.725%0.25326%0.258SS..G310 helixtrans-56.9-30.1-176.2-2835.7000114.1E350 K360 Q419 K423 R424E350-P421 HydrophobicContact CB-CG 4.42Å; E350-P421 VanDerWaalsContact CD-CG 3.49Å; E350-P421 HydrophobicContact CG-CG 3.78Å; K360-P421 HydrophobicContact CB-CB 3.89Å; K360-P421 WeakPolarHBondContact CD-O 3.46Å; K360-P421 WeakPolarHBondContact CG-O 3.23Å; Q419-P421 WeakPolarHBondContact O-CD 3.22Å; P421-K423 VanDerWaalsContact C-N 3.29Å; P421-K423 PolarHBondContact O-N 3.25Å; P421-R424 WeakPolarHBondContact O-CB 3.4Å; P421-R424 PolarHBondContact O-N 3.41Å
422R96.3Very high97.9Very high237 Ų23754.9 Ų54.989%0.89426%0.256SS*.G310 helixtrans-70.2-23.4179.4-63.9-179.5-179.7-179.6-0.8113.5E420 R424E420-R422 PolarHBondContact O-N 2.7Å; R422-R424 VanDerWaalsContact C-N 3.34Å
423K98Very high97.9Very high118 Ų11857.8 Ų57.851%0.51327%0.268SS..G310 helixtrans-81.3-17.1176.9-68.2-178.1175.8168.10112.4E418 E420 P421E418-K423 HydrophobicContact CB-CB 3.91Å; E418-K423 HydrophobicContact CG-CB 4.03Å; E420-K423 HydrophobicContact CB-CB 4.46Å; E420-K423 HydrophobicContact CB-CD 4.07Å; E420-K423 HydrophobicContact CB-CG 4.09Å; E420-K423 WeakPolarHBondContact O-CB 3.19Å; E420-K423 PolarHBondContact O-N 3.22Å; E420-K423 WeakPolarHBondContact OE1-CE 3.31Å; E420-K423 IonicContact OE1-NZ 3.29Å; E420-K423 PolarHBondContact OE1-NZ 2.96Å; P421-K423 VanDerWaalsContact C-N 3.29Å; P421-K423 PolarHBondContact O-N 3.25Å
424R98.5Very high97.9Very high3 Ų357.9 Ų57.91%0.01127%0.268CS..SBendtrans-69.7132.8175.2-59.2175.4-163.2151.59109.7E350 K360 V363 C416 E418 P421 R422E350-R424 IonicContact OE1-CZ 3.98Å; E350-R424 IonicContact OE1-NH1 2.74Å; E350-R424 PolarHBondContact OE1-NH1 3.23Å; E350-R424 IonicContact OE1-NH2 2.68Å; E350-R424 PolarHBondContact OE1-NH2 2.9Å; E350-R424 IonicContact OE2-CZ 2.79Å; E350-R424 IonicContact OE2-NH1 3.74Å; E350-R424 IonicContact OE2-NH2 3.8Å; E350-R424 PolarHBondContact OE2-NH2 2.7Å; K360-R424 HydrophobicContact CD-CB 4.32Å; K360-R424 PolarHBondContact NZ-O 3.17Å; K360-R424 WeakPolarHBondContact O-CD 3.39Å; K360-R424 PolarHBondContact O-NH1 3.49Å; V363-R424 HydrophobicContact CG1-CB 3.9Å; C416-R424 VanDerWaalsContact O-CD 3.25Å; C416-R424 WeakPolarHBondContact O-CD 3.44Å; E418-R424 HydrophobicContact CB-CG 3.85Å; E418-R424 PolarHBondContact O-NE 2.77Å; E418-R424 PolarHBondContact O-NH2 3.31Å; P421-R424 WeakPolarHBondContact O-CB 3.4Å; P421-R424 PolarHBondContact O-N 3.41Å; R422-R424 VanDerWaalsContact C-N 3.34Å
425P98.1Very high97.8Very high23 Ų2356.1 Ų56.115%0.14926%0.262CS..PPolyproline II helixtrans-63.1163.8177.228-35.6000111.9K360 L415 K429 L430K360-P425 PolarHBondContact NZ-O 2.97Å; L415-P425 HydrophobicContact CB-CG 4.18Å; P425-K429 HydrophobicContact CB-CB 4.12Å; P425-K429 HydrophobicContact CB-CG 4.31Å; P425-L430 HydrophobicContact CB-CD2 4.45Å; P425-L430 HydrophobicContact CB-CG 4.32Å; P425-L430 HydrophobicContact CG-CD1 4.29Å; P425-L430 HydrophobicContact CG-CD2 3.53Å; P425-L430 HydrophobicContact CG-CG 3.78Å
426G98.1Very high97.7Very high19 Ų1958.4 Ų58.420%0.19627%0.271CS..PPolyproline II helixtrans-78.5165.7165.500000111S428 K429 L430G426-S428 VanDerWaalsContact C-N 3.28Å; G426-S428 PolarHBondContact O-N 2.76Å; G426-K429 PolarHBondContact O-N 3.49Å; G426-K429 VanDerWaalsContact O-N 3.15Å; G426-L430 PolarHBondContact O-N 3.36Å
427F98.6Very high97.5Very high1 Ų159.9 Ų59.90%0.00428%0.278CS..Hα-helixtrans-64-34.1-178.8-80.3-76.2000112.5C293 M296 E297 E300 D362 V363 Y366 K429 L430 R431C293-F427 PolarHBondContact SG-O 2.88Å; C293-F427 VanDerWaalsContact SG-O 3.4Å; M296-F427 HydrophobicContact CB-CD1 3.49Å; M296-F427 VanDerWaalsContact CB-CD1 3.49Å; M296-F427 HydrophobicContact CB-CD2 3.97Å; M296-F427 HydrophobicContact CB-CE1 3.35Å; M296-F427 HydrophobicContact CB-CE2 3.83Å; M296-F427 HydrophobicContact CB-CG 3.81Å; M296-F427 HydrophobicContact CB-CZ 3.53Å; M296-F427 HydrophobicContact CE-CE2 4.09Å; M296-F427 HydrophobicContact CE-CZ 3.93Å; M296-F427 HydrophobicContact CG-CD1 4.47Å; M296-F427 HydrophobicContact CG-CE1 3.9Å; M296-F427 HydrophobicContact CG-CZ 4Å; E297-F427 HydrophobicContact CB-CB 3.81Å; E297-F427 HydrophobicContact CG-CB 4.46Å; E300-F427 HydrophobicContact CB-CD2 4.24Å; E300-F427 PolarHBondContact OE2-N 3.36Å; D362-F427 HydrophobicContact CB-CE2 4.24Å; D362-F427 HydrophobicContact CB-CZ 4.24Å; V363-F427 HydrophobicContact CG2-CD2 4Å; V363-F427 HydrophobicContact CG2-CE1 4.41Å; V363-F427 HydrophobicContact CG2-CE2 3.61Å; V363-F427 HydrophobicContact CG2-CZ 3.84Å; Y366-F427 HydrophobicContact CD1-CE1 4.06Å; Y366-F427 HydrophobicContact CD2-CE1 4.21Å; Y366-F427 AromaticContact CG-CE1 3.76Å; Y366-F427 HydrophobicContact CG-CE1 3.76Å; F427-K429 VanDerWaalsContact C-N 3.29Å; F427-K429 PolarHBondContact O-N 3.35Å; F427-L430 HydrophobicContact CD1-CD1 4.14Å; F427-L430 HydrophobicContact CE1-CD1 4.44Å; F427-L430 WeakPolarHBondContact O-CB 3.44Å; F427-L430 PolarHBondContact O-N 3.43Å; F427-L430 VanDerWaalsContact O-N 3.11Å; F427-R431 PolarHBondContact O-N 2.98Å
428S98.3Very high97.3Very high47 Ų4761 Ų6133%0.32928%0.284SS..Hα-helixtrans-56-42.9173.9-156.70000112.6E297 G426 R431 E432E297-S428 VanDerWaalsContact OE1-CA 3.28Å; E297-S428 WeakPolarHBondContact OE1-CA 3.33Å; E297-S428 WeakPolarHBondContact OE1-CB 3.49Å; E297-S428 PolarHBondContact OE1-OG 2.88Å; G426-S428 VanDerWaalsContact C-N 3.28Å; G426-S428 PolarHBondContact O-N 2.76Å; S428-R431 WeakPolarHBondContact O-CB 3.49Å; S428-R431 PolarHBondContact O-N 3.5Å; S428-E432 PolarHBondContact O-N 3.23Å
429K98.4Very high97.1Very high101 Ų10161.2 Ų61.244%0.43929%0.294SS..Hα-helixtrans-73.1-30.3178.8-17055.7172.1-1770112.9P425 G426 F427 E432 K433P425-K429 HydrophobicContact CB-CB 4.12Å; P425-K429 HydrophobicContact CB-CG 4.31Å; G426-K429 PolarHBondContact O-N 3.49Å; G426-K429 VanDerWaalsContact O-N 3.15Å; F427-K429 VanDerWaalsContact C-N 3.29Å; F427-K429 PolarHBondContact O-N 3.35Å; K429-E432 WeakPolarHBondContact CD-OE2 3.38Å; K429-E432 IonicContact NZ-OE2 2.83Å; K429-E432 PolarHBondContact NZ-OE2 3.14Å; K429-K433 WeakPolarHBondContact O-CG 3.49Å; K429-K433 PolarHBondContact O-N 3.4Å
430L98.7Very high96.8Very high0 Ų064.1 Ų64.10%031%0.305CS..Hα-helixtrans-68.9-41173.6-68.7169.8000110.8V363 Y366 I412 P425 G426 F427 K433 L434V363-L430 HydrophobicContact CG1-CD1 3.97Å; V363-L430 HydrophobicContact CG2-CD1 4.37Å; Y366-L430 HydrophobicContact CD1-CD1 3.94Å; Y366-L430 HydrophobicContact CE1-CD1 4.19Å; I412-L430 HydrophobicContact CG2-CD2 3.64Å; P425-L430 HydrophobicContact CB-CD2 4.45Å; P425-L430 HydrophobicContact CB-CG 4.32Å; P425-L430 HydrophobicContact CG-CD1 4.29Å; P425-L430 HydrophobicContact CG-CD2 3.53Å; P425-L430 HydrophobicContact CG-CG 3.78Å; G426-L430 PolarHBondContact O-N 3.36Å; F427-L430 HydrophobicContact CD1-CD1 4.14Å; F427-L430 HydrophobicContact CE1-CD1 4.44Å; F427-L430 WeakPolarHBondContact O-CB 3.44Å; F427-L430 PolarHBondContact O-N 3.43Å; F427-L430 VanDerWaalsContact O-N 3.11Å; L430-K433 PolarHBondContact O-N 3.13Å; L430-L434 WeakPolarHBondContact O-CD1 3.19Å; L430-L434 WeakPolarHBondContact O-CG 3.47Å; L430-L434 PolarHBondContact O-N 3.24Å
431R98.4Very high96.1Very high66 Ų6662 Ų6225%0.24930%0.299CS..Hα-helixtrans-56.9-53.1175.2-176.2178.96190.3-0.1111.2L290 C293 E294 E297 F427 S428 K433 L434 E435L290-R431 HydrophobicContact CD1-CG 3.65Å; C293-R431 PolarHBondContact SG-N 3.1Å; C293-R431 VanDerWaalsContact SG-N 3.4Å; E294-R431 HydrophobicContact CG-CG 4.31Å; E297-R431 IonicContact OE1-NE 2.67Å; E297-R431 IonicContact OE1-NH2 3.92Å; E297-R431 WeakPolarHBondContact OE2-CD 2.91Å; E297-R431 IonicContact OE2-CZ 3.5Å; E297-R431 IonicContact OE2-NE 3.12Å; E297-R431 PolarHBondContact OE2-NE 3.03Å; F427-R431 PolarHBondContact O-N 2.98Å; S428-R431 WeakPolarHBondContact O-CB 3.49Å; S428-R431 PolarHBondContact O-N 3.5Å; R431-K433 PolarHBondContact O-N 3.03Å; R431-L434 PolarHBondContact O-N 2.87Å; R431-E435 HydrophobicContact CG-CG 4.46Å; R431-E435 WeakPolarHBondContact CG-OE1 3.48Å; R431-E435 IonicContact CZ-OE1 2.69Å; R431-E435 IonicContact NH1-OE1 3.52Å; R431-E435 PolarHBondContact NH1-OE1 3.31Å; R431-E435 IonicContact NH1-OE2 3.54Å; R431-E435 WeakPolarHBondContact O-CG 3.5Å; R431-E435 PolarHBondContact O-N 2.97Å
432E98.2Very high95Very high70 Ų7063.6 Ų63.633%0.32731%0.311SS..Hα-helixtrans-53.4-41.8177-71.2174.3-169.500112.4S428 K429 Q436S428-E432 PolarHBondContact O-N 3.23Å; K429-E432 WeakPolarHBondContact CD-OE2 3.38Å; K429-E432 IonicContact NZ-OE2 2.83Å; K429-E432 PolarHBondContact NZ-OE2 3.14Å; E432-Q436 VanDerWaalsContact O-CG 3.27Å; E432-Q436 WeakPolarHBondContact O-CG 3.47Å; E432-Q436 PolarHBondContact O-N 3.43Å; E432-Q436 VanDerWaalsContact O-N 3.14Å
433K98.1Very high93Very high65 Ų6558.1 Ų58.128%0.28331%0.306SS..Hα-helixtrans-68.5-39.3178.9-73.6176.6174.2-66.20112I412 L415 K429 L430 R431 Q436 E437I412-K433 HydrophobicContact CD1-CB 3.85Å; I412-K433 HydrophobicContact CG1-CB 4.07Å; I412-K433 HydrophobicContact CG1-CD 4.41Å; L415-K433 HydrophobicContact CD1-CD 3.89Å; K429-K433 WeakPolarHBondContact O-CG 3.49Å; K429-K433 PolarHBondContact O-N 3.4Å; L430-K433 PolarHBondContact O-N 3.13Å; R431-K433 PolarHBondContact O-N 3.03Å; K433-Q436 WeakPolarHBondContact O-CB 3.3Å; K433-Q436 PolarHBondContact O-N 3.43Å; K433-E437 WeakPolarHBondContact O-CG 3.38Å; K433-E437 PolarHBondContact O-N 3.03Å
434L97.5Very high90.4Very high2 Ų257.5 Ų57.51%0.0132%0.317CS..Hα-helixtrans-68.2-39.1177.2-71159000111.9L286 L290 C293 Y366 I412 L430 R431 Q436 E437 L438L286-L434 HydrophobicContact CD2-CD2 4.2Å; L290-L434 HydrophobicContact CD1-CB 4.07Å; C293-L434 HydrophobicContact CB-CD1 3.85Å; Y366-L434 HydrophobicContact CE1-CD1 4.36Å; Y366-L434 WeakPolarHBondContact OH-CD1 3.45Å; I412-L434 HydrophobicContact CD1-CD2 3.82Å; I412-L434 HydrophobicContact CD1-CG 4.04Å; L430-L434 WeakPolarHBondContact O-CD1 3.19Å; L430-L434 WeakPolarHBondContact O-CG 3.47Å; L430-L434 PolarHBondContact O-N 3.24Å; R431-L434 PolarHBondContact O-N 2.87Å; L434-Q436 VanDerWaalsContact C-N 3.29Å; L434-Q436 PolarHBondContact O-N 3.45Å; L434-E437 PolarHBondContact O-N 2.83Å; L434-L438 WeakPolarHBondContact O-CB 3.27Å; L434-L438 PolarHBondContact O-N 2.89Å
435E97.3Very high87.8Confident71 Ų7162.9 Ų62.933%0.33236%0.355SS..Hα-helixtrans-59.9-40.9173.5-71.2170.1174.800111.3L290 R431 L438 S439L290-E435 HydrophobicContact CD1-CG 3.8Å; L290-E435 HydrophobicContact CD2-CG 4.19Å; R431-E435 HydrophobicContact CG-CG 4.46Å; R431-E435 WeakPolarHBondContact CG-OE1 3.48Å; R431-E435 IonicContact CZ-OE1 2.69Å; R431-E435 IonicContact NH1-OE1 3.52Å; R431-E435 PolarHBondContact NH1-OE1 3.31Å; R431-E435 IonicContact NH1-OE2 3.54Å; R431-E435 WeakPolarHBondContact O-CG 3.5Å; R431-E435 PolarHBondContact O-N 2.97Å; E435-L438 PolarHBondContact O-N 3.41Å; E435-S439 PolarHBondContact O-N 3.05Å; E435-S439 PolarHBondContact O-OG 2.94Å
436Q96.4Very high85.2Confident105 Ų10566.5 Ų66.549%0.49139%0.387SS..Hα-helixtrans-65.6-36.2174-70.9169.512.100113.2E432 K433 L434 S439 K440E432-Q436 VanDerWaalsContact O-CG 3.27Å; E432-Q436 WeakPolarHBondContact O-CG 3.47Å; E432-Q436 PolarHBondContact O-N 3.43Å; E432-Q436 VanDerWaalsContact O-N 3.14Å; K433-Q436 WeakPolarHBondContact O-CB 3.3Å; K433-Q436 PolarHBondContact O-N 3.43Å; L434-Q436 VanDerWaalsContact C-N 3.29Å; L434-Q436 PolarHBondContact O-N 3.45Å; Q436-S439 PolarHBondContact O-OG 2.95Å; Q436-K440 WeakPolarHBondContact O-CG 3.2Å
437E95.4Very high82.3Confident31 Ų3170.3 Ų70.315%0.14542%0.416CS..Hα-helixtrans-72.4-38.4174.8-67.8-53.4124.900111.7L286 G408 I412 K433 L434 K440 T441L286-E437 HydrophobicContact CD1-CB 4.28Å; L286-E437 HydrophobicContact CD2-CB 3.97Å; G408-E437 WeakPolarHBondContact CA-OE2 3.37Å; I412-E437 HydrophobicContact CD1-CG 4.17Å; K433-E437 WeakPolarHBondContact O-CG 3.38Å; K433-E437 PolarHBondContact O-N 3.03Å; L434-E437 PolarHBondContact O-N 2.83Å; E437-K440 WeakPolarHBondContact O-CB 3.48Å; E437-K440 PolarHBondContact O-N 3.47Å; E437-K440 IonicContact OE1-NZ 3.68Å; E437-K440 PolarHBondContact OE1-NZ 3.09Å; E437-K440 IonicContact OE2-NZ 3.64Å; E437-T441 PolarHBondContact O-N 3.11Å
438L93.9Very high79.4Confident27 Ų2773.8 Ų73.814%0.14145%0.453CS..Hα-helixtrans-66.2-39178.5-173.165.4000111.7A283 L286 L290 L434 E435 K440 T441 S442A283-L438 HydrophobicContact CB-CD1 4.49Å; L286-L438 HydrophobicContact CB-CD1 3.77Å; L286-L438 HydrophobicContact CD1-CD1 4.45Å; L290-L438 HydrophobicContact CD2-CD2 4.11Å; L434-L438 WeakPolarHBondContact O-CB 3.27Å; L434-L438 PolarHBondContact O-N 2.89Å; E435-L438 PolarHBondContact O-N 3.41Å; L438-K440 VanDerWaalsContact C-N 3.27Å; L438-K440 PolarHBondContact O-N 3.5Å; L438-T441 PolarHBondContact O-N 3.2Å; L438-T441 VanDerWaalsContact O-N 3.08Å; L438-T441 PolarHBondContact O-OG1 3.48Å; L438-S442 PolarHBondContact O-N 3.11Å
439S92.9Very high76.6Confident79 Ų7977 Ų7755%0.55248%0.476SS*.Hα-helixtrans-63.3-32.5177.367.80000112.7E435 Q436 T441 S442E435-S439 PolarHBondContact O-N 3.05Å; E435-S439 PolarHBondContact O-OG 2.94Å; Q436-S439 PolarHBondContact O-OG 2.95Å; S439-T441 VanDerWaalsContact C-N 3.27Å; S439-T441 PolarHBondContact O-N 3.05Å; S439-S442 PolarHBondContact O-N 3.1Å
440K90.8Very high73.7Confident140 Ų14081.5 Ų81.561%0.60950%0.498SS*.Hα-helixtrans-67.7-25.4174.3-64.9168.1-169.3174.40113.4Q436 E437 L438Q436-K440 WeakPolarHBondContact O-CG 3.2Å; E437-K440 WeakPolarHBondContact O-CB 3.48Å; E437-K440 PolarHBondContact O-N 3.47Å; E437-K440 IonicContact OE1-NZ 3.68Å; E437-K440 PolarHBondContact OE1-NZ 3.09Å; E437-K440 IonicContact OE2-NZ 3.64Å; L438-K440 VanDerWaalsContact C-N 3.27Å; L438-K440 PolarHBondContact O-N 3.5Å
441T80.7Confident70.7Confident57 Ų5791 Ų9135%0.3554%0.543SS..Hα-helixtrans-86.2-11.2178.758.70000113.8L286 E437 L438 S439L286-T441 HydrophobicContact CD1-CG2 3.77Å; E437-T441 PolarHBondContact O-N 3.11Å; L438-T441 PolarHBondContact O-N 3.2Å; L438-T441 VanDerWaalsContact O-N 3.08Å; L438-T441 PolarHBondContact O-OG1 3.48Å; S439-T441 VanDerWaalsContact C-N 3.27Å; S439-T441 PolarHBondContact O-N 3.05Å
442S71.8Confident67.8Low73 Ų7392.9 Ų92.951%0.5157%0.572SS.*SBendtrans-80.4130.2174-59.80000109.2L438 S439 S444L438-S442 PolarHBondContact O-N 3.11Å; S439-S442 PolarHBondContact O-N 3.1Å; S442-S444 PolarHBondContact O-N 3.33Å
443P55Low65Low122 Ų12294.1 Ų94.179%0.79259%0.594SS**  trans-60.7126.9176.523.4-30000108.9S445P443-S445 PolarHBondContact O-N 2.68Å
444S44.3Very low62.3Low105 Ų105100.8 Ų100.873%0.73462%0.623SS**  trans-61.395.2173.856.20000109.7S442 A446S442-S444 PolarHBondContact O-N 3.33Å; S444-A446 PolarHBondContact O-N 3.46Å
445S43.1Very low59.9Low117 Ų117107.7 Ų107.782%0.81867%0.666SS**SBendtrans-66120.1157.655.20000107.7P443P443-S445 PolarHBondContact O-N 2.68Å
446A43.3Very low57.3Low99 Ų99107.4 Ų107.482%0.81868%0.682SS**SBendtrans93.567.2176.900000117.6S444S444-A446 PolarHBondContact O-N 3.46Å
447A37.7Very low54.7Low98 Ų98110.6 Ų110.681%0.8170%0.701SS**SBendtrans-153.763.7147.500000109.3
448G37.9Very low52.2Low75 Ų75120.8 Ų120.877%0.77374%0.739SS**SBendtrans-170.343.8-175.100000113.5
449S38.8Very low49.6Very low115 Ų115128.6 Ų128.680%0.80480%0.795SS**SBendtrans-163.953.4172.248.70000112
450Q37.6Very low47.5Very low195 Ų195131.1 Ų131.191%0.91181%0.807SS**SBendtrans-15159.4160.8-75.9-162.1-11.500111.1
451E36.3Very low45.2Very low200 Ų200130.6 Ų130.694%0.93582%0.818SS**SBendtrans-156.634.5159.8-131171.2-170.800114.5
452A36.4Very low43.2Very low104 Ų104134.7 Ų134.786%0.8684%0.844SS**SBendtrans-132.954.3169.900000110.5
453A39.8Very low41.5Very low97 Ų97138.3 Ų138.380%0.80286%0.863SS**SBendtrans-15444.8170.600000111.3
454K42.2Very low40.7Very low204 Ų204139.3 Ų139.389%0.88787%0.868SS**SBendtrans-144.444.8169.3-84.4-165.2-179.9174.30112.4
455T45.7Very low40.5Very low147 Ų147141.6 Ų141.690%0.90288%0.877SS**SBendtrans-150.486.4163.636.70000109
456G44Very low40.3Very low65 Ų65143.4 Ų143.467%0.6788%0.881SS**  trans16855.5175.200000114
457L41.8Very low40Very low173 Ų173146.8 Ų146.891%0.90689%0.886SS**  trans-17387157.1-104.5135.1000109.5
458R41.4Very low40.2Very low245 Ų245150.8 Ų150.893%0.92589%0.892SS**  trans-145118141.5-76.8-161175.7172-2.5108.3
459S40.9Very low40.4Very low190 Ų190157.7 Ų157.7100%1.32990%0.903SS**  trans-39.30156.849.90000113.8

Retrieved 459 of 459 residues in 382.9 ms (Link to these results)