A0A096LZK6_POEFO Loading...

XK-related protein

Phospholipid scramblase that promotes phosphatidylserine exposure on apoptotic cell surface. Phosphatidylserine is a specific marker only present at the surface of apoptotic cells and acts as a specific signal for engulfment.

AlphaFold DB , UniProt , Accession A0A096LZK6, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 408 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	V	39.5	Very low	31.7	Very low	148 Å²	148	134.5 Å²	134.5	90%	0.897	65%	0.65	S	S	*	*				0	-65.2	0	-173.8	0	0	0	0	111.8	H3 Y4 T5	V1-H3 VanDerWaalsContact C-N 3.31Å; V1-H3 PolarHBondContact O-N 3.49Å; V1-H3 VanDerWaalsContact O-N 3.1Å; V1-Y4 WeakPolarHBondContact O-CB 3.26Å; V1-Y4 PolarHBondContact O-N 3.28Å; V1-T5 PolarHBondContact O-N 3.25Å; V1-T5 PolarHBondContact O-OG1 3.43Å
2	Y	27.4	Very low	32	Very low	209 Å²	209	127.1 Å²	127.1	82%	0.82	63%	0.627	S	S	*	*	H	α-helix	trans	-46.7	-42.5	-177.3	-68.1	-79.7	0	0	0	116.1	Y4 T5 C6	Y2-Y4 VanDerWaalsContact C-N 3.32Å; Y2-Y4 PolarHBondContact O-N 3.28Å; Y2-T5 PolarHBondContact O-N 3.39Å; Y2-C6 PolarHBondContact O-N 3.49Å
3	H	30.3	Very low	33	Very low	170 Å²	170	127 Å²	127	79%	0.787	62%	0.624	S	S	*	*	H	α-helix	trans	-60.1	-36.1	176.9	-124.1	-92.9	0	0	0	113.9	V1 F7	V1-H3 VanDerWaalsContact C-N 3.31Å; V1-H3 PolarHBondContact O-N 3.49Å; V1-H3 VanDerWaalsContact O-N 3.1Å; H3-F7 WeakPolarHBondContact O-CB 3.42Å; H3-F7 PolarHBondContact O-N 2.92Å
4	Y	28.6	Very low	33.6	Very low	184 Å²	184	120.2 Å²	120.2	72%	0.722	60%	0.595	S	S	*	*	H	α-helix	trans	-75.9	-33	177.2	-85.3	-93.6	0	0	0	112.3	V1 Y2 K8	V1-Y4 WeakPolarHBondContact O-CB 3.26Å; V1-Y4 PolarHBondContact O-N 3.28Å; Y2-Y4 VanDerWaalsContact C-N 3.32Å; Y2-Y4 PolarHBondContact O-N 3.28Å; Y4-K8 WeakPolarHBondContact O-CB 3.42Å; Y4-K8 WeakPolarHBondContact O-CG 3.18Å; Y4-K8 PolarHBondContact O-N 3.45Å
5	T	29.9	Very low	34.3	Very low	79 Å²	79	122.1 Å²	122.1	49%	0.485	60%	0.598	S	S	.	*	H	α-helix	trans	-68.7	-44.2	176.9	-40.3	0	0	0	0	110.8	V1 Y2 K8 F9	V1-T5 PolarHBondContact O-N 3.25Å; V1-T5 PolarHBondContact O-OG1 3.43Å; Y2-T5 PolarHBondContact O-N 3.39Å; T5-K8 PolarHBondContact O-N 3.2Å; T5-F9 PolarHBondContact O-N 3.36Å
6	C	30	Very low	35.2	Very low	95 Å²	95	125.6 Å²	125.6	64%	0.642	60%	0.604	S	S	*	*	H	α-helix	trans	-61.6	-44.3	176.4	-164.6	0	0	0	0	111.8	Y2 K8 F9 G10	Y2-C6 PolarHBondContact O-N 3.49Å; C6-K8 PolarHBondContact O-N 3.35Å; C6-F9 PolarHBondContact O-N 2.91Å; C6-G10 PolarHBondContact O-N 2.94Å
7	F	32.5	Very low	36.1	Very low	143 Å²	143	122.9 Å²	122.9	63%	0.627	59%	0.594	S	S	*	*	H	α-helix	trans	-63	-40.8	177	-162.5	-94.9	0	0	0	112.4	H3 F11	H3-F7 WeakPolarHBondContact O-CB 3.42Å; H3-F7 PolarHBondContact O-N 2.92Å; F7-F11 HydrophobicContact CD1-CD2 4.15Å; F7-F11 AromaticContact CE1-CD2 3.66Å; F7-F11 HydrophobicContact CE1-CD2 3.66Å; F7-F11 AromaticContact CE1-CE2 3.72Å; F7-F11 HydrophobicContact CE1-CE2 3.72Å; F7-F11 HydrophobicContact CZ-CD2 4.14Å; F7-F11 AromaticContact CZ-CE2 3.93Å; F7-F11 HydrophobicContact CZ-CE2 3.93Å; F7-F11 PolarHBondContact O-N 2.95Å
8	K	28.4	Very low	36.9	Very low	156 Å²	156	121.3 Å²	121.3	68%	0.678	59%	0.585	S	S	*	*	H	α-helix	trans	-66	-35.6	173.8	-80	-172.1	175.2	-175	0	113.1	Y4 T5 C6 A12	Y4-K8 WeakPolarHBondContact O-CB 3.42Å; Y4-K8 WeakPolarHBondContact O-CG 3.18Å; Y4-K8 PolarHBondContact O-N 3.45Å; T5-K8 PolarHBondContact O-N 3.2Å; C6-K8 PolarHBondContact O-N 3.35Å; K8-A12 WeakPolarHBondContact O-CB 3.19Å; K8-A12 PolarHBondContact O-N 3.28Å
9	F	31.4	Very low	37.4	Very low	143 Å²	143	120 Å²	120	63%	0.627	58%	0.581	S	S	*	*	H	α-helix	trans	-68.4	-44.2	178.6	-141	-90.6	0	0	0	111.4	T5 C6 A12 Q13	T5-F9 PolarHBondContact O-N 3.36Å; C6-F9 PolarHBondContact O-N 2.91Å; F9-A12 PolarHBondContact O-N 3.33Å; F9-Q13 PolarHBondContact O-N 2.84Å
10	G	38.4	Very low	37.9	Very low	33 Å²	33	116.3 Å²	116.3	34%	0.34	57%	0.568	S	S	.	*	H	α-helix	trans	-58.7	-47.5	171.7	0	0	0	0	0	112.4	C6 A12 Q13 C14	C6-G10 PolarHBondContact O-N 2.94Å; G10-A12 VanDerWaalsContact C-N 3.3Å; G10-A12 PolarHBondContact O-N 3.4Å; G10-Q13 PolarHBondContact O-N 2.89Å; G10-C14 PolarHBondContact O-N 3.48Å; G10-C14 PolarHBondContact O-SG 3.28Å; G10-C14 VanDerWaalsContact O-SG 3.42Å
11	F	32.3	Very low	38.8	Very low	120 Å²	120	111.4 Å²	111.4	53%	0.526	55%	0.545	S	S	.	.	H	α-helix	trans	-62.3	-34.3	176.5	-117.3	-86.7	0	0	0	113.6	F7 K15	F7-F11 HydrophobicContact CD1-CD2 4.15Å; F7-F11 AromaticContact CE1-CD2 3.66Å; F7-F11 HydrophobicContact CE1-CD2 3.66Å; F7-F11 AromaticContact CE1-CE2 3.72Å; F7-F11 HydrophobicContact CE1-CE2 3.72Å; F7-F11 HydrophobicContact CZ-CD2 4.14Å; F7-F11 AromaticContact CZ-CE2 3.93Å; F7-F11 HydrophobicContact CZ-CE2 3.93Å; F7-F11 PolarHBondContact O-N 2.95Å; F11-K15 PolarHBondContact O-N 2.85Å; F11-K15 VanDerWaalsContact O-N 3.1Å
12	A	34.8	Very low	39.7	Very low	45 Å²	45	108.8 Å²	108.8	37%	0.372	53%	0.525	S	S	.	.	H	α-helix	trans	-69.6	-46	175.3	0	0	0	0	0	111.2	K8 F9 G10 K15 Y16	K8-A12 WeakPolarHBondContact O-CB 3.19Å; K8-A12 PolarHBondContact O-N 3.28Å; F9-A12 PolarHBondContact O-N 3.33Å; G10-A12 VanDerWaalsContact C-N 3.3Å; G10-A12 PolarHBondContact O-N 3.4Å; A12-K15 PolarHBondContact O-N 3.32Å; A12-Y16 WeakPolarHBondContact O-CD2 3.38Å; A12-Y16 PolarHBondContact O-N 3.5Å
13	Q	45.6	Very low	40.9	Very low	126 Å²	126	102.5 Å²	102.5	59%	0.589	51%	0.511	S	S	*	.	H	α-helix	trans	-60.6	-44.4	174.4	-78.3	-178.3	-72.9	0	0	111.7	F9 G10 K15 Y16 L17	F9-Q13 PolarHBondContact O-N 2.84Å; G10-Q13 PolarHBondContact O-N 2.89Å; Q13-K15 VanDerWaalsContact C-N 3.33Å; Q13-K15 PolarHBondContact O-N 2.9Å; Q13-Y16 PolarHBondContact O-N 3.19Å; Q13-L17 WeakPolarHBondContact O-CB 3.25Å; Q13-L17 PolarHBondContact O-N 3.11Å
14	C	41.7	Very low	42.3	Very low	32 Å²	32	99.2 Å²	99.2	22%	0.216	49%	0.491	C	S	.	.	H	α-helix	trans	-57.4	-43	174.2	-72	0	0	0	0	112.2	G10 Y16 L17 Q18 E68	G10-C14 PolarHBondContact O-N 3.48Å; G10-C14 PolarHBondContact O-SG 3.28Å; G10-C14 VanDerWaalsContact O-SG 3.42Å; C14-Y16 PolarHBondContact O-N 2.94Å; C14-L17 PolarHBondContact O-N 3.48Å; C14-Q18 WeakPolarHBondContact O-CB 3.36Å; C14-Q18 WeakPolarHBondContact O-CG 3.32Å; C14-Q18 PolarHBondContact O-N 3.47Å; C14-E68 PolarHBondContact SG-OE1 3.27Å
15	K	43.3	Very low	43.6	Very low	149 Å²	149	94.6 Å²	94.6	65%	0.648	47%	0.473	S	S	*	.	H	α-helix	trans	-63.2	-41.4	175.9	-81	-172.1	174.5	-172.7	0	113.2	F11 A12 Q13 L19	F11-K15 PolarHBondContact O-N 2.85Å; F11-K15 VanDerWaalsContact O-N 3.1Å; A12-K15 PolarHBondContact O-N 3.32Å; Q13-K15 VanDerWaalsContact C-N 3.33Å; Q13-K15 PolarHBondContact O-N 2.9Å; K15-L19 WeakPolarHBondContact O-CB 3.38Å; K15-L19 PolarHBondContact O-N 3.14Å
16	Y	49.3	Very low	45	Very low	177 Å²	177	96.7 Å²	96.7	69%	0.694	48%	0.476	S	S	*	.	H	α-helix	trans	-66.7	-37.8	174.4	-85.5	-79.3	0	0	0	112.1	A12 Q13 C14 S20	A12-Y16 WeakPolarHBondContact O-CD2 3.38Å; A12-Y16 PolarHBondContact O-N 3.5Å; Q13-Y16 PolarHBondContact O-N 3.19Å; C14-Y16 PolarHBondContact O-N 2.94Å; Y16-S20 WeakPolarHBondContact O-CB 3.48Å; Y16-S20 PolarHBondContact O-N 3.4Å
17	L	50.1	Low	46.3	Very low	81 Å²	81	98.7 Å²	98.7	42%	0.424	47%	0.47	S	S	.	.	H	α-helix	trans	-66.2	-50.1	177.9	-152.1	71.9	0	0	0	111	Q13 C14 L19 S20 V21 A64	Q13-L17 WeakPolarHBondContact O-CB 3.25Å; Q13-L17 PolarHBondContact O-N 3.11Å; C14-L17 PolarHBondContact O-N 3.48Å; L17-L19 PolarHBondContact O-N 2.97Å; L17-S20 WeakPolarHBondContact O-CB 3.42Å; L17-S20 PolarHBondContact O-N 2.85Å; L17-S20 PolarHBondContact O-OG 2.89Å; L17-V21 WeakPolarHBondContact O-CG2 3.18Å; L17-V21 PolarHBondContact O-N 3.36Å; L17-A64 HydrophobicContact CD2-CB 3.47Å; L17-A64 VanDerWaalsContact CD2-CB 3.47Å; L17-A64 HydrophobicContact CG-CB 3.97Å
18	Q	50.5	Low	47.4	Very low	93 Å²	93	92.5 Å²	92.5	44%	0.435	44%	0.444	S	S	.	.	H	α-helix	trans	-64.4	-36.2	176.5	-68.8	-179.4	7.7	0	0	112.3	C14 V21 L22 E68	C14-Q18 WeakPolarHBondContact O-CB 3.36Å; C14-Q18 WeakPolarHBondContact O-CG 3.32Å; C14-Q18 PolarHBondContact O-N 3.47Å; Q18-V21 PolarHBondContact O-N 2.97Å; Q18-L22 WeakPolarHBondContact O-CB 3.3Å; Q18-L22 PolarHBondContact O-N 3.41Å; Q18-E68 PolarHBondContact NE2-OE1 3.17Å; Q18-E68 PolarHBondContact NE2-OE2 3.45Å
19	L	46.9	Very low	48.9	Very low	97 Å²	97	90.5 Å²	90.5	51%	0.508	44%	0.439	S	S	.	.	H	α-helix	trans	-66	-39.7	172.6	-174.7	65.2	0	0	0	111.7	K15 L17 V21 L22 C23	K15-L19 WeakPolarHBondContact O-CB 3.38Å; K15-L19 PolarHBondContact O-N 3.14Å; L17-L19 PolarHBondContact O-N 2.97Å; L19-V21 VanDerWaalsContact C-N 3.3Å; L19-V21 PolarHBondContact O-N 3.4Å; L19-L22 PolarHBondContact O-N 3.14Å; L19-C23 WeakPolarHBondContact O-CB 3.4Å; L19-C23 PolarHBondContact O-N 3.28Å; L19-C23 PolarHBondContact O-SG 2.84Å
20	S	47.8	Very low	50.4	Low	46 Å²	46	90 Å²	90	32%	0.322	43%	0.433	S	S	.	.	H	α-helix	trans	-63.1	-37.3	175.7	82.9	0	0	0	0	112.2	Y16 L17 R24	Y16-S20 WeakPolarHBondContact O-CB 3.48Å; Y16-S20 PolarHBondContact O-N 3.4Å; L17-S20 WeakPolarHBondContact O-CB 3.42Å; L17-S20 PolarHBondContact O-N 2.85Å; L17-S20 PolarHBondContact O-OG 2.89Å; S20-R24 VanDerWaalsContact O-CB 3.27Å; S20-R24 WeakPolarHBondContact O-CB 3.4Å; S20-R24 WeakPolarHBondContact O-CD 3.43Å; S20-R24 VanDerWaalsContact O-CG 3.27Å; S20-R24 WeakPolarHBondContact O-CG 3.04Å; S20-R24 PolarHBondContact O-N 3.28Å; S20-R24 VanDerWaalsContact O-N 3.16Å
21	V	56.4	Low	51.3	Low	14 Å²	14	89.2 Å²	89.2	9%	0.085	42%	0.421	C	S	.	.	H	α-helix	trans	-66.6	-48.6	173	168.4	0	0	0	0	110.4	L17 Q18 L19 R24 Y25 H61	L17-V21 WeakPolarHBondContact O-CG2 3.18Å; L17-V21 PolarHBondContact O-N 3.36Å; Q18-V21 PolarHBondContact O-N 2.97Å; L19-V21 VanDerWaalsContact C-N 3.3Å; L19-V21 PolarHBondContact O-N 3.4Å; V21-R24 CarbonylContact O-C 3.58Å; V21-R24 WeakPolarHBondContact O-CB 3.37Å; V21-R24 PolarHBondContact O-N 3.16Å; V21-R24 VanDerWaalsContact O-N 3.16Å; V21-Y25 HydrophobicContact CG1-CD2 3.65Å; V21-Y25 HydrophobicContact CG1-CE2 3.71Å; V21-Y25 WeakPolarHBondContact O-CD2 3.25Å; V21-Y25 PolarHBondContact O-N 2.97Å; V21-H61 HydrophobicContact CG1-CB 4Å; V21-H61 HydrophobicContact CG2-CB 4.28Å
22	L	57.2	Low	52.5	Low	93 Å²	93	84.7 Å²	84.7	49%	0.487	41%	0.408	S	S	.	.	H	α-helix	trans	-59.5	-49.5	178	-99.8	150.4	0	0	0	112.6	Q18 L19 R24 Y25 F26	Q18-L22 WeakPolarHBondContact O-CB 3.3Å; Q18-L22 PolarHBondContact O-N 3.41Å; L19-L22 PolarHBondContact O-N 3.14Å; L22-R24 PolarHBondContact O-N 3.1Å; L22-Y25 PolarHBondContact O-N 3.27Å; L22-F26 HydrophobicContact CD2-CD2 4.41Å; L22-F26 HydrophobicContact CD2-CE2 3.78Å; L22-F26 HydrophobicContact CD2-CZ 4.49Å; L22-F26 WeakPolarHBondContact O-CD2 3.21Å; L22-F26 PolarHBondContact O-N 2.97Å
23	C	52.7	Low	54	Low	76 Å²	76	86.6 Å²	86.6	51%	0.514	41%	0.411	S	S	.	.	H	α-helix	trans	-58.3	-36.3	175.7	-73.9	0	0	0	0	112.2	L19 R27	L19-C23 WeakPolarHBondContact O-CB 3.4Å; L19-C23 PolarHBondContact O-N 3.28Å; L19-C23 PolarHBondContact O-SG 2.84Å; C23-R27 PolarHBondContact O-N 2.88Å; C23-R27 VanDerWaalsContact O-N 3.13Å
24	R	59.8	Low	54.8	Low	101 Å²	101	85.1 Å²	85.1	38%	0.381	40%	0.401	S	S	.	.	H	α-helix	trans	-68.9	-45	174.8	-85	170.8	176.5	-134.4	4.4	112.2	S20 V21 L22 F26 R27 T28 V57	S20-R24 VanDerWaalsContact O-CB 3.27Å; S20-R24 WeakPolarHBondContact O-CB 3.4Å; S20-R24 WeakPolarHBondContact O-CD 3.43Å; S20-R24 VanDerWaalsContact O-CG 3.27Å; S20-R24 WeakPolarHBondContact O-CG 3.04Å; S20-R24 PolarHBondContact O-N 3.28Å; S20-R24 VanDerWaalsContact O-N 3.16Å; V21-R24 CarbonylContact O-C 3.58Å; V21-R24 WeakPolarHBondContact O-CB 3.37Å; V21-R24 PolarHBondContact O-N 3.16Å; V21-R24 VanDerWaalsContact O-N 3.16Å; L22-R24 PolarHBondContact O-N 3.1Å; R24-F26 PolarHBondContact O-N 3.31Å; R24-R27 WeakPolarHBondContact O-CB 3.5Å; R24-R27 PolarHBondContact O-N 2.92Å; R24-R27 VanDerWaalsContact O-N 3.12Å; R24-T28 PolarHBondContact O-N 3.25Å; R24-T28 PolarHBondContact O-OG1 3.42Å; R24-V57 HydrophobicContact CB-CB 4.34Å; R24-V57 HydrophobicContact CB-CG1 3.78Å; R24-V57 HydrophobicContact CB-CG2 3.56Å; R24-V57 HydrophobicContact CG-CG2 3.89Å
25	Y	57.4	Low	55.3	Low	87 Å²	87	84 Å²	84	34%	0.341	39%	0.393	S	S	.	.	H	α-helix	trans	-58.5	-43.7	172.7	-94.8	-82.5	0	0	0	112.8	V21 L22 R27 T28 M29 V57 H61	V21-Y25 HydrophobicContact CG1-CD2 3.65Å; V21-Y25 HydrophobicContact CG1-CE2 3.71Å; V21-Y25 WeakPolarHBondContact O-CD2 3.25Å; V21-Y25 PolarHBondContact O-N 2.97Å; L22-Y25 PolarHBondContact O-N 3.27Å; Y25-R27 VanDerWaalsContact C-N 3.29Å; Y25-R27 PolarHBondContact O-N 3.08Å; Y25-T28 PolarHBondContact O-N 2.93Å; Y25-M29 WeakPolarHBondContact O-CB 3.33Å; Y25-M29 PolarHBondContact O-N 2.96Å; Y25-V57 HydrophobicContact CD2-CG1 4.17Å; Y25-V57 HydrophobicContact CE2-CG1 4.28Å; Y25-H61 HydrophobicContact CE2-CB 4.34Å; Y25-H61 AromaticContact CE2-CD2 3.8Å; Y25-H61 AromaticContact CZ-CD2 3.96Å; Y25-H61 PolarHBondContact OH-CD2 3.38Å
26	F	59.4	Low	56	Low	124 Å²	124	87.5 Å²	87.5	54%	0.544	40%	0.402	S	S	.	.	H	α-helix	trans	-60.1	-39.2	174.3	-80.7	-65.1	0	0	0	112	L22 R24 M29 Y30	L22-F26 HydrophobicContact CD2-CD2 4.41Å; L22-F26 HydrophobicContact CD2-CE2 3.78Å; L22-F26 HydrophobicContact CD2-CZ 4.49Å; L22-F26 WeakPolarHBondContact O-CD2 3.21Å; L22-F26 PolarHBondContact O-N 2.97Å; R24-F26 PolarHBondContact O-N 3.31Å; F26-M29 HydrophobicContact CD1-CE 4.19Å; F26-M29 HydrophobicContact CE1-CE 4.39Å; F26-M29 PolarHBondContact O-N 3.33Å; F26-Y30 WeakPolarHBondContact O-CB 3.38Å; F26-Y30 PolarHBondContact O-N 3.47Å
27	R	56.1	Low	56.6	Low	136 Å²	136	86.5 Å²	86.5	51%	0.513	40%	0.403	S	S	.	.	H	α-helix	trans	-65.3	-40.5	175.9	-165.1	175	-173.4	-120.6	7.7	112	C23 R24 Y25 Y30 L31 E53	C23-R27 PolarHBondContact O-N 2.88Å; C23-R27 VanDerWaalsContact O-N 3.13Å; R24-R27 WeakPolarHBondContact O-CB 3.5Å; R24-R27 PolarHBondContact O-N 2.92Å; R24-R27 VanDerWaalsContact O-N 3.12Å; Y25-R27 VanDerWaalsContact C-N 3.29Å; Y25-R27 PolarHBondContact O-N 3.08Å; R27-Y30 PolarHBondContact O-N 2.86Å; R27-L31 HydrophobicContact CG-CD1 4.48Å; R27-L31 WeakPolarHBondContact O-CB 3.32Å; R27-L31 VanDerWaalsContact O-CG 3.3Å; R27-L31 WeakPolarHBondContact O-CG 3.35Å; R27-L31 PolarHBondContact O-N 2.93Å; R27-E53 IonicContact CZ-OE2 3.85Å; R27-E53 VanDerWaalsContact NH1-CD 3.34Å; R27-E53 IonicContact NH1-OE1 2.71Å; R27-E53 IonicContact NH1-OE2 3.7Å; R27-E53 PolarHBondContact NH1-OE2 3.04Å
28	T	55.8	Low	56.8	Low	13 Å²	13	83.8 Å²	83.8	8%	0.08	40%	0.395	C	S	.	.	H	α-helix	trans	-67.2	-41.4	174.8	-40.1	0	0	0	0	111.9	R24 Y25 L31 G32 M50 F54	R24-T28 PolarHBondContact O-N 3.25Å; R24-T28 PolarHBondContact O-OG1 3.42Å; Y25-T28 PolarHBondContact O-N 2.93Å; T28-L31 PolarHBondContact O-N 2.83Å; T28-G32 PolarHBondContact O-N 3.38Å; T28-M50 HydrophobicContact CG2-CG 3.98Å; T28-F54 HydrophobicContact CG2-CB 3.78Å; T28-F54 HydrophobicContact CG2-CD2 4Å; T28-F54 HydrophobicContact CG2-CG 4.32Å
29	M	59.3	Low	57.1	Low	115 Å²	115	83.3 Å²	83.3	57%	0.567	40%	0.402	S	S	*	.	H	α-helix	trans	-64.6	-41.1	176.4	-168.2	170.7	75.8	0	0	111.6	Y25 F26 G32 I33	Y25-M29 WeakPolarHBondContact O-CB 3.33Å; Y25-M29 PolarHBondContact O-N 2.96Å; F26-M29 HydrophobicContact CD1-CE 4.19Å; F26-M29 HydrophobicContact CE1-CE 4.39Å; F26-M29 PolarHBondContact O-N 3.33Å; M29-G32 PolarHBondContact O-N 2.85Å; M29-I33 HydrophobicContact CG-CD1 4.17Å; M29-I33 VanDerWaalsContact O-CG1 3.3Å; M29-I33 WeakPolarHBondContact O-CG1 3.34Å; M29-I33 PolarHBondContact O-N 2.86Å
30	Y	63.7	Low	57.4	Low	132 Å²	132	88.1 Å²	88.1	52%	0.518	42%	0.419	S	S	.	.	H	α-helix	trans	-60.4	-44.8	172.1	172.9	-94.6	0	0	0	112.1	F26 R27 G32 I33 R34	F26-Y30 WeakPolarHBondContact O-CB 3.38Å; F26-Y30 PolarHBondContact O-N 3.47Å; R27-Y30 PolarHBondContact O-N 2.86Å; Y30-G32 PolarHBondContact O-N 2.87Å; Y30-I33 PolarHBondContact O-N 3.38Å; Y30-R34 WeakPolarHBondContact O-CB 3.38Å; Y30-R34 PolarHBondContact O-N 2.87Å; Y30-R34 PolarHBondContact OH-NH1 3.22Å
31	L	57.4	Low	57.7	Low	17 Å²	17	88 Å²	88	9%	0.089	42%	0.418	C	S	.	.	H	α-helix	trans	-62.8	-39.2	175.2	-74.9	164.7	0	0	0	112.2	R27 T28 R34 S35 M50 E53	R27-L31 HydrophobicContact CG-CD1 4.48Å; R27-L31 WeakPolarHBondContact O-CB 3.32Å; R27-L31 VanDerWaalsContact O-CG 3.3Å; R27-L31 WeakPolarHBondContact O-CG 3.35Å; R27-L31 PolarHBondContact O-N 2.93Å; T28-L31 PolarHBondContact O-N 2.83Å; L31-R34 PolarHBondContact O-N 3.49Å; L31-S35 WeakPolarHBondContact O-CB 3.23Å; L31-S35 PolarHBondContact O-N 2.95Å; L31-M50 HydrophobicContact CB-CB 4.07Å; L31-M50 HydrophobicContact CB-CG 4.13Å; L31-E53 HydrophobicContact CD1-CB 4.33Å; L31-E53 HydrophobicContact CD1-CG 4.2Å
32	G	57.5	Low	57.9	Low	24 Å²	24	91.4 Å²	91.4	25%	0.247	43%	0.433	C	S	.	.	H	α-helix	trans	-67.8	-39.9	175.8	0	0	0	0	0	113.7	T28 M29 Y30 S35 R36	T28-G32 PolarHBondContact O-N 3.38Å; M29-G32 PolarHBondContact O-N 2.85Å; Y30-G32 PolarHBondContact O-N 2.87Å; G32-S35 WeakPolarHBondContact O-CB 3.49Å; G32-R36 PolarHBondContact O-N 3.02Å
33	I	66.7	Low	58.2	Low	86 Å²	86	91 Å²	91	44%	0.441	43%	0.428	S	S	.	.	H	α-helix	trans	-63.3	-46.1	173.8	-69.2	163.7	0	0	0	110.2	M29 Y30 R36 Q37	M29-I33 HydrophobicContact CG-CD1 4.17Å; M29-I33 VanDerWaalsContact O-CG1 3.3Å; M29-I33 WeakPolarHBondContact O-CG1 3.34Å; M29-I33 PolarHBondContact O-N 2.86Å; Y30-I33 PolarHBondContact O-N 3.38Å; I33-R36 WeakPolarHBondContact O-CB 3.44Å; I33-R36 PolarHBondContact O-N 2.98Å; I33-Q37 WeakPolarHBondContact O-CG 3.23Å; I33-Q37 PolarHBondContact O-N 2.82Å
34	R	61.5	Low	58.6	Low	95 Å²	95	91.8 Å²	91.8	36%	0.358	42%	0.42	S	S	.	.	H	α-helix	trans	-69.2	-35.5	179.8	-177.7	167.4	148	174	-1.4	112.9	Y30 L31 R36 Q37 G38 Y46	Y30-R34 WeakPolarHBondContact O-CB 3.38Å; Y30-R34 PolarHBondContact O-N 2.87Å; Y30-R34 PolarHBondContact OH-NH1 3.22Å; L31-R34 PolarHBondContact O-N 3.49Å; R34-R36 PolarHBondContact O-N 3.2Å; R34-Q37 PolarHBondContact O-N 3.24Å; R34-Q37 VanDerWaalsContact O-N 3.15Å; R34-G38 PolarHBondContact O-N 2.99Å; R34-G38 VanDerWaalsContact O-N 3.1Å; R34-Y46 PolarHBondContact NH2-OH 3.02Å
35	S	51.6	Low	58.8	Low	7 Å²	7	91.2 Å²	91.2	5%	0.049	42%	0.422	C	S	.	.	H	α-helix	trans	-52.8	-44.9	168.6	178.5	0	0	0	0	110.8	L31 G32 Q37 H43	L31-S35 WeakPolarHBondContact O-CB 3.23Å; L31-S35 PolarHBondContact O-N 2.95Å; G32-S35 WeakPolarHBondContact O-CB 3.49Å; S35-Q37 VanDerWaalsContact C-N 3.25Å; S35-Q37 PolarHBondContact O-N 2.71Å; S35-H43 PolarHBondContact O-CD2 3.07Å
36	R	58	Low	59.1	Low	224 Å²	224	89 Å²	89	85%	0.845	41%	0.414	S	S	*	.	T	Hydrogen-bonded Turn	trans	-74.7	-10.9	-177.2	-149.9	177.5	-172.2	-162.8	1.6	114.4	G32 I33 R34	G32-R36 PolarHBondContact O-N 3.02Å; I33-R36 WeakPolarHBondContact O-CB 3.44Å; I33-R36 PolarHBondContact O-N 2.98Å; R34-R36 PolarHBondContact O-N 3.2Å
37	Q	62.1	Low	59.5	Low	155 Å²	155	86.9 Å²	86.9	72%	0.724	40%	0.403	S	S	*	.	T	Hydrogen-bonded Turn	trans	-108.3	-13	-178.9	-69.4	174.2	-13.1	0	0	113.4	I33 R34 S35	I33-Q37 WeakPolarHBondContact O-CG 3.23Å; I33-Q37 PolarHBondContact O-N 2.82Å; R34-Q37 PolarHBondContact O-N 3.24Å; R34-Q37 VanDerWaalsContact O-N 3.15Å; S35-Q37 VanDerWaalsContact C-N 3.25Å; S35-Q37 PolarHBondContact O-N 2.71Å
38	G	55.3	Low	59.9	Low	24 Å²	24	81.1 Å²	81.1	25%	0.247	38%	0.381	C	S	.	.	S	Bend	trans	-78.3	159.5	-178.8	0	0	0	0	0	114.4	R34	R34-G38 PolarHBondContact O-N 2.99Å; R34-G38 VanDerWaalsContact O-N 3.1Å
39	S	56.2	Low	60.4	Low	83 Å²	83	86 Å²	86	58%	0.58	40%	0.401	S	S	*	.			trans	-64.8	159.2	173.7	-174.3	0	0	0	0	111.8	S41 E42 H43	S39-S41 PolarHBondContact O-N 3.36Å; S39-E42 PolarHBondContact O-N 2.7Å; S39-H43 PolarHBondContact O-N 3.4Å
40	K	54.6	Low	60.8	Low	199 Å²	199	82.4 Å²	82.4	87%	0.865	38%	0.383	S	S	*	.	H	α-helix	trans	-52.1	-34.6	-172.2	-73.8	-176.7	176.9	178.8	0	114.7
41	S	53.5	Low	61.1	Low	43 Å²	43	76.5 Å²	76.5	30%	0.301	36%	0.361	S	S	.	.	H	α-helix	trans	-73.6	-47.7	176.9	174.1	0	0	0	0	112	S39 H43	S39-S41 PolarHBondContact O-N 3.36Å; S41-H43 VanDerWaalsContact C-N 3.33Å; S41-H43 PolarHBondContact O-N 2.98Å
42	E	60.4	Low	61.5	Low	86 Å²	86	76.1 Å²	76.1	40%	0.402	36%	0.358	S	S	.	.	H	α-helix	trans	-65.2	-34.2	177.2	-72.1	-167.2	107.3	0	0	113.1	S39 W44 Q45 Y46	S39-E42 PolarHBondContact O-N 2.7Å; E42-W44 PolarHBondContact O-N 2.87Å; E42-Q45 PolarHBondContact O-N 3.19Å; E42-Q45 VanDerWaalsContact O-N 3.13Å; E42-Y46 HydrophobicContact CB-CD2 3.89Å; E42-Y46 HydrophobicContact CB-CE2 3.76Å; E42-Y46 HydrophobicContact CG-CE2 4.23Å; E42-Y46 WeakPolarHBondContact O-CD2 3.27Å; E42-Y46 PolarHBondContact O-N 3.01Å; E42-Y46 WeakPolarHBondContact OE1-CE2 3.31Å; E42-Y46 PolarHBondContact OE1-OH 3.38Å
43	H	62.9	Low	62	Low	83 Å²	83	76.3 Å²	76.3	38%	0.384	35%	0.353	S	S	.	.	H	α-helix	trans	-52.6	-42.3	-178.8	-176.4	-71.4	0	0	0	111.9	S35 S39 S41 Y47	S35-H43 PolarHBondContact O-CD2 3.07Å; S39-H43 PolarHBondContact O-N 3.4Å; S41-H43 VanDerWaalsContact C-N 3.33Å; S41-H43 PolarHBondContact O-N 2.98Å; H43-Y47 WeakPolarHBondContact O-CB 3.25Å; H43-Y47 PolarHBondContact O-N 3.14Å
44	W	61.1	Low	62.2	Low	93 Å²	93	75.5 Å²	75.5	35%	0.352	35%	0.346	S	S	.	.	H	α-helix	trans	-66.4	-46.5	178.3	174.8	-102.1	0	0	0	112.3	E42 Y46 Y47 W48 P387	E42-W44 PolarHBondContact O-N 2.87Å; W44-Y46 PolarHBondContact O-N 3.27Å; W44-Y47 PolarHBondContact O-N 3.5Å; W44-W48 AromaticContact CD2-CD1 3.49Å; W44-W48 VanDerWaalsContact CD2-CD1 3.49Å; W44-W48 AromaticContact CD2-NE1 3.44Å; W44-W48 AromaticContact CE2-CD1 3.33Å; W44-W48 AromaticContact CE2-NE1 3.14Å; W44-W48 AromaticContact CE3-CD1 3.82Å; W44-W48 AromaticContact CE3-NE1 3.41Å; W44-W48 AromaticContact CH2-CE2 3.74Å; W44-W48 AromaticContact CH2-CZ2 3.92Å; W44-W48 HydrophobicContact CH2-CZ2 3.92Å; W44-W48 AromaticContact CH2-NE1 2.99Å; W44-W48 AromaticContact CZ2-CD1 3.66Å; W44-W48 AromaticContact CZ2-CE2 3.83Å; W44-W48 HydrophobicContact CZ2-CZ2 4.31Å; W44-W48 AromaticContact CZ2-NE1 2.96Å; W44-W48 HydrophobicContact CZ3-CZ2 4.47Å; W44-W48 AromaticContact CZ3-NE1 3.18Å; W44-W48 AromaticContact NE1-CD1 3.64Å; W44-W48 AromaticContact NE1-NE1 3.9Å; W44-W48 PolarHBondContact O-N 3.35Å; W44-P387 HydrophobicContact CZ2-CB 3.72Å; W44-P387 HydrophobicContact CZ2-CG 4.16Å
45	Q	63.6	Low	62.6	Low	89 Å²	89	71.1 Å²	71.1	42%	0.416	33%	0.331	S	S	.	.	H	α-helix	trans	-64.1	-42.4	179.6	-60.7	-173.9	14.3	0	0	111.8	E42 K49 L379	E42-Q45 PolarHBondContact O-N 3.19Å; E42-Q45 VanDerWaalsContact O-N 3.13Å; Q45-K49 VanDerWaalsContact O-CB 3.26Å; Q45-K49 WeakPolarHBondContact O-CB 3.2Å; Q45-K49 PolarHBondContact O-N 3.3Å; Q45-L379 HydrophobicContact CG-CD1 4.48Å; Q45-L379 HydrophobicContact CG-CD2 4.22Å
46	Y	64.4	Low	63.4	Low	42 Å²	42	72.7 Å²	72.7	17%	0.165	34%	0.338	C	S	.	.	H	α-helix	trans	-68.5	-35.9	175.5	-71.1	-58.6	0	0	0	112.4	R34 E42 W44 M50	R34-Y46 PolarHBondContact NH2-OH 3.02Å; E42-Y46 HydrophobicContact CB-CD2 3.89Å; E42-Y46 HydrophobicContact CB-CE2 3.76Å; E42-Y46 HydrophobicContact CG-CE2 4.23Å; E42-Y46 WeakPolarHBondContact O-CD2 3.27Å; E42-Y46 PolarHBondContact O-N 3.01Å; E42-Y46 WeakPolarHBondContact OE1-CE2 3.31Å; E42-Y46 PolarHBondContact OE1-OH 3.38Å; W44-Y46 PolarHBondContact O-N 3.27Å; Y46-M50 VanDerWaalsContact O-CB 3.23Å; Y46-M50 WeakPolarHBondContact O-CB 3.35Å; Y46-M50 PolarHBondContact O-N 2.88Å
47	Y	67.8	Low	64	Low	79 Å²	79	62.2 Å²	62.2	31%	0.31	30%	0.299	S	S	.	.	H	α-helix	trans	-61	-52.2	174.4	173.5	-99.8	0	0	0	111.8	H43 W44 K49 M50 V51	H43-Y47 WeakPolarHBondContact O-CB 3.25Å; H43-Y47 PolarHBondContact O-N 3.14Å; W44-Y47 PolarHBondContact O-N 3.5Å; Y47-K49 PolarHBondContact O-N 2.91Å; Y47-M50 HydrophobicContact CD2-CE 4.23Å; Y47-M50 HydrophobicContact CE2-CE 4.34Å; Y47-M50 CarbonylContact O-C 3.55Å; Y47-M50 WeakPolarHBondContact O-CA 3.47Å; Y47-M50 WeakPolarHBondContact O-CB 3.26Å; Y47-M50 PolarHBondContact O-N 2.87Å; Y47-M50 VanDerWaalsContact O-N 3.11Å; Y47-V51 HydrophobicContact CD1-CG2 4.34Å; Y47-V51 HydrophobicContact CD2-CG2 4.36Å; Y47-V51 HydrophobicContact CE1-CG2 3.93Å; Y47-V51 HydrophobicContact CE2-CG2 3.96Å; Y47-V51 WeakPolarHBondContact O-CG2 3.39Å; Y47-V51 PolarHBondContact O-N 3.04Å
48	W	64	Low	64.5	Low	15 Å²	15	55 Å²	55	6%	0.057	27%	0.266	C	S	.	.	H	α-helix	trans	-64.2	-40.9	178	-80	96.2	0	0	0	113	W44 M50 V51 Y52 D117	W44-W48 AromaticContact CD2-CD1 3.49Å; W44-W48 VanDerWaalsContact CD2-CD1 3.49Å; W44-W48 AromaticContact CD2-NE1 3.44Å; W44-W48 AromaticContact CE2-CD1 3.33Å; W44-W48 AromaticContact CE2-NE1 3.14Å; W44-W48 AromaticContact CE3-CD1 3.82Å; W44-W48 AromaticContact CE3-NE1 3.41Å; W44-W48 AromaticContact CH2-CE2 3.74Å; W44-W48 AromaticContact CH2-CZ2 3.92Å; W44-W48 HydrophobicContact CH2-CZ2 3.92Å; W44-W48 AromaticContact CH2-NE1 2.99Å; W44-W48 AromaticContact CZ2-CD1 3.66Å; W44-W48 AromaticContact CZ2-CE2 3.83Å; W44-W48 HydrophobicContact CZ2-CZ2 4.31Å; W44-W48 AromaticContact CZ2-NE1 2.96Å; W44-W48 HydrophobicContact CZ3-CZ2 4.47Å; W44-W48 AromaticContact CZ3-NE1 3.18Å; W44-W48 AromaticContact NE1-CD1 3.64Å; W44-W48 AromaticContact NE1-NE1 3.9Å; W44-W48 PolarHBondContact O-N 3.35Å; W48-M50 PolarHBondContact O-N 3.38Å; W48-V51 PolarHBondContact O-N 3.17Å; W48-Y52 HydrophobicContact CB-CD2 4.48Å; W48-Y52 HydrophobicContact CB-CE2 4.2Å; W48-Y52 HydrophobicContact CE3-CD1 4.37Å; W48-Y52 AromaticContact CE3-CE1 3.71Å; W48-Y52 HydrophobicContact CE3-CE1 3.71Å; W48-Y52 HydrophobicContact CE3-CE2 4.09Å; W48-Y52 AromaticContact CE3-CZ 3.56Å; W48-Y52 AromaticContact CZ3-CE1 3.97Å; W48-Y52 HydrophobicContact CZ3-CE1 3.97Å; W48-Y52 WeakPolarHBondContact O-CB 3.14Å; W48-Y52 WeakPolarHBondContact O-CD2 3.3Å; W48-Y52 VanDerWaalsContact O-CG 3.26Å; W48-Y52 PolarHBondContact O-N 3.42Å; W48-D117 HydrophobicContact CH2-CB 4.38Å; W48-D117 VanDerWaalsContact CZ2-OD1 3.24Å; W48-D117 WeakPolarHBondContact CZ2-OD1 3.43Å; W48-D117 WeakPolarHBondContact CZ2-OD2 3.29Å
49	K	66.4	Low	65.3	Low	114 Å²	114	56 Å²	56	50%	0.496	27%	0.265	S	S	.	.	H	α-helix	trans	-61.2	-36	174	-165.3	169.3	-173.6	170.5	0	111.7	Q45 Y47 E53	Q45-K49 VanDerWaalsContact O-CB 3.26Å; Q45-K49 WeakPolarHBondContact O-CB 3.2Å; Q45-K49 PolarHBondContact O-N 3.3Å; Y47-K49 PolarHBondContact O-N 2.91Å; K49-E53 WeakPolarHBondContact O-CB 3.39Å; K49-E53 WeakPolarHBondContact O-CG 3.34Å; K49-E53 PolarHBondContact O-N 2.97Å; K49-E53 VanDerWaalsContact O-N 3.13Å
50	M	68.7	Low	66	Low	40 Å²	40	55.2 Å²	55.2	20%	0.197	25%	0.254	C	S	.	.	H	α-helix	trans	-69.4	-45.4	172.8	-177.4	-141.5	67.3	0	0	112	T28 L31 Y46 Y47 W48 Y52 F54	T28-M50 HydrophobicContact CG2-CG 3.98Å; L31-M50 HydrophobicContact CB-CB 4.07Å; L31-M50 HydrophobicContact CB-CG 4.13Å; Y46-M50 VanDerWaalsContact O-CB 3.23Å; Y46-M50 WeakPolarHBondContact O-CB 3.35Å; Y46-M50 PolarHBondContact O-N 2.88Å; Y47-M50 HydrophobicContact CD2-CE 4.23Å; Y47-M50 HydrophobicContact CE2-CE 4.34Å; Y47-M50 CarbonylContact O-C 3.55Å; Y47-M50 WeakPolarHBondContact O-CA 3.47Å; Y47-M50 WeakPolarHBondContact O-CB 3.26Å; Y47-M50 PolarHBondContact O-N 2.87Å; Y47-M50 VanDerWaalsContact O-N 3.11Å; W48-M50 PolarHBondContact O-N 3.38Å; M50-Y52 PolarHBondContact O-N 2.86Å; M50-F54 WeakPolarHBondContact O-CB 3.33Å; M50-F54 PolarHBondContact O-N 3.35Å
51	V	69.1	Low	67.1	Low	9 Å²	9	48.1 Å²	48.1	6%	0.055	22%	0.223	C	C	.	.	H	α-helix	trans	-60.5	-44.9	178.2	171	0	0	0	0	111.1	Y47 W48 F54 A55	Y47-V51 HydrophobicContact CD1-CG2 4.34Å; Y47-V51 HydrophobicContact CD2-CG2 4.36Å; Y47-V51 HydrophobicContact CE1-CG2 3.93Å; Y47-V51 HydrophobicContact CE2-CG2 3.96Å; Y47-V51 WeakPolarHBondContact O-CG2 3.39Å; Y47-V51 PolarHBondContact O-N 3.04Å; W48-V51 PolarHBondContact O-N 3.17Å; V51-F54 WeakPolarHBondContact O-CB 3.25Å; V51-F54 PolarHBondContact O-N 3.3Å; V51-A55 PolarHBondContact O-N 3.47Å
52	Y	66.5	Low	68.2	Low	8 Å²	8	46.1 Å²	46.1	3%	0.031	21%	0.21	C	C	.	.	H	α-helix	trans	-68.5	-45.3	179.8	-64.4	-36.5	0	0	0	113	W48 M50 F54 A55 D56 H368 D371 R372 R375	W48-Y52 HydrophobicContact CB-CD2 4.48Å; W48-Y52 HydrophobicContact CB-CE2 4.2Å; W48-Y52 HydrophobicContact CE3-CD1 4.37Å; W48-Y52 AromaticContact CE3-CE1 3.71Å; W48-Y52 HydrophobicContact CE3-CE1 3.71Å; W48-Y52 HydrophobicContact CE3-CE2 4.09Å; W48-Y52 AromaticContact CE3-CZ 3.56Å; W48-Y52 AromaticContact CZ3-CE1 3.97Å; W48-Y52 HydrophobicContact CZ3-CE1 3.97Å; W48-Y52 WeakPolarHBondContact O-CB 3.14Å; W48-Y52 WeakPolarHBondContact O-CD2 3.3Å; W48-Y52 VanDerWaalsContact O-CG 3.26Å; W48-Y52 PolarHBondContact O-N 3.42Å; M50-Y52 PolarHBondContact O-N 2.86Å; Y52-F54 VanDerWaalsContact C-N 3.26Å; Y52-F54 PolarHBondContact O-N 3.08Å; Y52-A55 PolarHBondContact O-N 2.93Å; Y52-D56 PolarHBondContact O-N 3.49Å; Y52-H368 WeakPolarHBondContact CA-NE2 3.3Å; Y52-H368 VanDerWaalsContact CB-NE2 3.33Å; Y52-H368 WeakPolarHBondContact CB-NE2 3.46Å; Y52-H368 AromaticContact CD1-CD2 3.24Å; Y52-H368 WeakPolarHBondContact CD1-CD2 3.46Å; Y52-H368 AromaticContact CD1-NE2 3.24Å; Y52-H368 WeakPolarHBondContact CD1-NE2 3.36Å; Y52-H368 AromaticContact CE1-CD2 3.83Å; Y52-H368 AromaticContact CG-NE2 3.63Å; Y52-H368 PolarHBondContact O-NE2 2.92Å; Y52-D371 PolarHBondContact OH-OD2 3.24Å; Y52-R372 HydrophobicContact CD2-CB 4.03Å; Y52-R372 HydrophobicContact CD2-CG 3.93Å; Y52-R372 HydrophobicContact CE2-CB 3.99Å; Y52-R372 HydrophobicContact CE2-CG 4.26Å; Y52-R372 HydrophobicContact CG-CB 4.5Å; Y52-R375 VanDerWaalsContact OH-CD 3.29Å; Y52-R375 WeakPolarHBondContact OH-CD 3.12Å; Y52-R375 PolarHBondContact OH-NE 3.38Å; Y52-R375 VanDerWaalsContact OH-NE 3.1Å
53	E	67.6	Low	68.9	Low	28 Å²	28	44.2 Å²	44.2	13%	0.131	20%	0.202	C	C	.	.	H	α-helix	trans	-64.7	-33.7	174	-61.9	-86.9	164	0	0	110.5	R27 L31 K49 V57 R372	R27-E53 IonicContact CZ-OE2 3.85Å; R27-E53 VanDerWaalsContact NH1-CD 3.34Å; R27-E53 IonicContact NH1-OE1 2.71Å; R27-E53 IonicContact NH1-OE2 3.7Å; R27-E53 PolarHBondContact NH1-OE2 3.04Å; L31-E53 HydrophobicContact CD1-CB 4.33Å; L31-E53 HydrophobicContact CD1-CG 4.2Å; K49-E53 WeakPolarHBondContact O-CB 3.39Å; K49-E53 WeakPolarHBondContact O-CG 3.34Å; K49-E53 PolarHBondContact O-N 2.97Å; K49-E53 VanDerWaalsContact O-N 3.13Å; E53-V57 VanDerWaalsContact O-CB 3.29Å; E53-V57 WeakPolarHBondContact O-CB 3.39Å; E53-V57 WeakPolarHBondContact O-CG2 3.35Å; E53-V57 PolarHBondContact O-N 3.38Å; E53-R372 IonicContact OE1-CZ 3.84Å; E53-R372 IonicContact OE1-NH2 3.21Å; E53-R372 PolarHBondContact OE1-NH2 3.35Å
54	F	71.1	Confident	69.5	Low	69 Å²	69	40.7 Å²	40.7	30%	0.303	19%	0.187	S	C	.	.	H	α-helix	trans	-63.8	-44.1	173.1	-178.1	-116	0	0	0	111.9	T28 M50 V51 Y52 V57 S58 A111	T28-F54 HydrophobicContact CG2-CB 3.78Å; T28-F54 HydrophobicContact CG2-CD2 4Å; T28-F54 HydrophobicContact CG2-CG 4.32Å; M50-F54 WeakPolarHBondContact O-CB 3.33Å; M50-F54 PolarHBondContact O-N 3.35Å; V51-F54 WeakPolarHBondContact O-CB 3.25Å; V51-F54 PolarHBondContact O-N 3.3Å; Y52-F54 VanDerWaalsContact C-N 3.26Å; Y52-F54 PolarHBondContact O-N 3.08Å; F54-V57 PolarHBondContact O-N 2.95Å; F54-S58 WeakPolarHBondContact O-CB 3.25Å; F54-S58 PolarHBondContact O-N 3.29Å; F54-S58 PolarHBondContact O-OG 3.16Å; F54-S58 VanDerWaalsContact O-OG 3.14Å; F54-A111 HydrophobicContact CD1-CB 3.77Å; F54-A111 HydrophobicContact CE1-CB 3.74Å
55	A	69.4	Low	70.3	Confident	4 Å²	4	37.1 Å²	37.1	3%	0.033	18%	0.175	C	C	.	.	H	α-helix	trans	-62	-47.4	177	0	0	0	0	0	112.3	V51 Y52 V57 S58 M59 A111	V51-A55 PolarHBondContact O-N 3.47Å; Y52-A55 PolarHBondContact O-N 2.93Å; A55-V57 VanDerWaalsContact C-N 3.29Å; A55-V57 PolarHBondContact O-N 2.86Å; A55-S58 PolarHBondContact O-N 3.27Å; A55-M59 PolarHBondContact O-N 2.95Å; A55-A111 HydrophobicContact CB-CB 4.34Å
56	D	69	Low	71	Confident	39 Å²	39	32.9 Å²	32.9	21%	0.209	16%	0.156	C	C	.	.	H	α-helix	trans	-56.3	-44.3	174.4	-73.1	-20.5	0	0	0	111.2	Y52 M59 L60 H368 R372	Y52-D56 PolarHBondContact O-N 3.49Å; D56-M59 PolarHBondContact O-N 2.88Å; D56-L60 WeakPolarHBondContact O-CD1 3.32Å; D56-L60 PolarHBondContact O-N 2.92Å; D56-H368 IonicContact OD1-CE1 2.66Å; D56-H368 PolarHBondContact OD1-CE1 3.49Å; D56-H368 IonicContact OD1-ND1 3.58Å; D56-R372 IonicContact OD2-CZ 3.6Å; D56-R372 IonicContact OD2-NH1 3.72Å; D56-R372 PolarHBondContact OD2-NH1 2.9Å; D56-R372 IonicContact OD2-NH2 3.77Å
57	V	70.7	Confident	71.5	Confident	4 Å²	4	34.3 Å²	34.3	2%	0.024	17%	0.166	C	C	.	.	H	α-helix	trans	-71.5	-41	-178.4	172.3	0	0	0	0	111.9	R24 Y25 E53 F54 A55 M59 L60 H61	R24-V57 HydrophobicContact CB-CB 4.34Å; R24-V57 HydrophobicContact CB-CG1 3.78Å; R24-V57 HydrophobicContact CB-CG2 3.56Å; R24-V57 HydrophobicContact CG-CG2 3.89Å; Y25-V57 HydrophobicContact CD2-CG1 4.17Å; Y25-V57 HydrophobicContact CE2-CG1 4.28Å; E53-V57 VanDerWaalsContact O-CB 3.29Å; E53-V57 WeakPolarHBondContact O-CB 3.39Å; E53-V57 WeakPolarHBondContact O-CG2 3.35Å; E53-V57 PolarHBondContact O-N 3.38Å; F54-V57 PolarHBondContact O-N 2.95Å; A55-V57 VanDerWaalsContact C-N 3.29Å; A55-V57 PolarHBondContact O-N 2.86Å; V57-M59 VanDerWaalsContact C-N 3.29Å; V57-M59 PolarHBondContact O-N 2.9Å; V57-L60 PolarHBondContact O-N 2.69Å; V57-H61 WeakPolarHBondContact O-CB 3.45Å; V57-H61 PolarHBondContact O-N 2.84Å
58	S	71.4	Confident	72.1	Confident	4 Å²	4	33.1 Å²	33.1	3%	0.028	16%	0.163	C	C	.	.	H	α-helix	trans	-62.2	-35.8	172.9	-71.5	0	0	0	0	111.8	F54 A55 L62	F54-S58 WeakPolarHBondContact O-CB 3.25Å; F54-S58 PolarHBondContact O-N 3.29Å; F54-S58 PolarHBondContact O-OG 3.16Å; F54-S58 VanDerWaalsContact O-OG 3.14Å; A55-S58 PolarHBondContact O-N 3.27Å; S58-L62 WeakPolarHBondContact O-CB 3.35Å; S58-L62 PolarHBondContact O-N 2.69Å
59	M	73.4	Confident	72.6	Confident	44 Å²	44	34 Å²	34	22%	0.217	17%	0.172	C	C	.	.	H	α-helix	trans	-64	-53.1	176.3	-161.1	178.3	73.6	0	0	111.7	A55 D56 V57 H61 L62 L63 Y108 F188	A55-M59 PolarHBondContact O-N 2.95Å; D56-M59 PolarHBondContact O-N 2.88Å; V57-M59 VanDerWaalsContact C-N 3.29Å; V57-M59 PolarHBondContact O-N 2.9Å; M59-H61 VanDerWaalsContact C-N 3.35Å; M59-H61 PolarHBondContact O-N 3.09Å; M59-L62 PolarHBondContact O-N 3.46Å; M59-L63 WeakPolarHBondContact O-CB 3.45Å; M59-L63 PolarHBondContact O-N 3.3Å; M59-Y108 HydrophobicContact CB-CD2 4.09Å; M59-Y108 HydrophobicContact CB-CE2 3.5Å; M59-Y108 HydrophobicContact CG-CE2 3.71Å; M59-F188 HydrophobicContact CE-CE2 4.33Å; M59-F188 HydrophobicContact SD-CE2 4.21Å
60	L	71.2	Confident	73.1	Confident	68 Å²	68	28.7 Å²	28.7	36%	0.356	15%	0.149	S	C	.	.	H	α-helix	trans	-66	-38	179.6	-84.8	88.7	0	0	0	112	D56 V57 L63 A64	D56-L60 WeakPolarHBondContact O-CD1 3.32Å; D56-L60 PolarHBondContact O-N 2.92Å; V57-L60 PolarHBondContact O-N 2.69Å; L60-L63 PolarHBondContact O-N 2.89Å; L60-A64 VanDerWaalsContact O-CB 3.26Å; L60-A64 WeakPolarHBondContact O-CB 3.23Å; L60-A64 PolarHBondContact O-N 3.37Å
61	H	77.4	Confident	73.6	Confident	49 Å²	49	30 Å²	30	23%	0.227	16%	0.16	C	C	.	.	H	α-helix	trans	-64.3	-47.9	176.5	177.5	36.6	0	0	0	111.4	V21 Y25 V57 M59 L63 A64 T65	V21-H61 HydrophobicContact CG1-CB 4Å; V21-H61 HydrophobicContact CG2-CB 4.28Å; Y25-H61 HydrophobicContact CE2-CB 4.34Å; Y25-H61 AromaticContact CE2-CD2 3.8Å; Y25-H61 AromaticContact CZ-CD2 3.96Å; Y25-H61 PolarHBondContact OH-CD2 3.38Å; V57-H61 WeakPolarHBondContact O-CB 3.45Å; V57-H61 PolarHBondContact O-N 2.84Å; M59-H61 VanDerWaalsContact C-N 3.35Å; M59-H61 PolarHBondContact O-N 3.09Å; H61-L63 VanDerWaalsContact C-N 3.33Å; H61-L63 PolarHBondContact O-N 3Å; H61-A64 PolarHBondContact O-N 3.47Å; H61-T65 PolarHBondContact CE1-OG1 3.33Å; H61-T65 PolarHBondContact ND1-OG1 3.37Å; H61-T65 VanDerWaalsContact O-CB 3.31Å; H61-T65 WeakPolarHBondContact O-CB 3.44Å; H61-T65 PolarHBondContact O-N 3.25Å; H61-T65 PolarHBondContact O-OG1 2.98Å; H61-T65 VanDerWaalsContact O-OG1 3.06Å
62	L	76.8	Confident	74.2	Confident	2 Å²	2	34.9 Å²	34.9	1%	0.01	18%	0.182	C	C	.	.	H	α-helix	trans	-55.5	-49.7	175.2	168.3	61.6	0	0	0	110.8	S58 M59 T65 F66 A104 L105 Y108 F201	S58-L62 WeakPolarHBondContact O-CB 3.35Å; S58-L62 PolarHBondContact O-N 2.69Å; M59-L62 PolarHBondContact O-N 3.46Å; L62-T65 PolarHBondContact O-N 3.13Å; L62-F66 WeakPolarHBondContact O-CB 3.31Å; L62-F66 PolarHBondContact O-N 3.43Å; L62-A104 HydrophobicContact CD1-CB 3.93Å; L62-L105 HydrophobicContact CD1-CB 4.48Å; L62-L105 HydrophobicContact CD1-CD2 3.69Å; L62-L105 HydrophobicContact CD1-CG 3.69Å; L62-L105 HydrophobicContact CD2-CD2 3.82Å; L62-L105 HydrophobicContact CG-CD2 4.35Å; L62-Y108 HydrophobicContact CD2-CD1 3.77Å; L62-Y108 HydrophobicContact CD2-CG 3.83Å; L62-F201 HydrophobicContact CD2-CD2 3.93Å; L62-F201 HydrophobicContact CD2-CE2 3.33Å; L62-F201 HydrophobicContact CD2-CZ 4.2Å
63	L	75.1	Confident	74.8	Confident	45 Å²	45	34.6 Å²	34.6	24%	0.236	18%	0.181	C	C	.	.	H	α-helix	trans	-59.9	-50.7	-179.9	176.3	62.5	0	0	0	111.7	M59 L60 H61 T65 F66 L67 V191 I195	M59-L63 WeakPolarHBondContact O-CB 3.45Å; M59-L63 PolarHBondContact O-N 3.3Å; L60-L63 PolarHBondContact O-N 2.89Å; H61-L63 VanDerWaalsContact C-N 3.33Å; H61-L63 PolarHBondContact O-N 3Å; L63-T65 PolarHBondContact O-N 3.06Å; L63-F66 PolarHBondContact O-N 2.74Å; L63-L67 HydrophobicContact CD1-CD1 3.78Å; L63-L67 HydrophobicContact CD1-CD2 4.33Å; L63-L67 HydrophobicContact CD1-CG 3.81Å; L63-L67 HydrophobicContact CG-CD1 3.94Å; L63-L67 HydrophobicContact CG-CG 4.32Å; L63-L67 WeakPolarHBondContact O-CB 3.23Å; L63-L67 WeakPolarHBondContact O-CG 3.35Å; L63-L67 PolarHBondContact O-N 3.28Å; L63-V191 HydrophobicContact CD1-CG1 3.4Å; L63-V191 VanDerWaalsContact CD1-CG1 3.4Å; L63-V191 HydrophobicContact CD2-CG1 3.36Å; L63-V191 HydrophobicContact CG-CG1 4Å; L63-I195 HydrophobicContact CD1-CD1 4.12Å; L63-I195 HydrophobicContact CD1-CG1 4.38Å
64	A	75.6	Confident	75.5	Confident	9 Å²	9	33.6 Å²	33.6	7%	0.074	18%	0.177	C	C	.	.	H	α-helix	trans	-56.1	-50.5	178.2	0	0	0	0	0	111.5	L17 L60 H61 F66 L67 E68	L17-A64 HydrophobicContact CD2-CB 3.47Å; L17-A64 VanDerWaalsContact CD2-CB 3.47Å; L17-A64 HydrophobicContact CG-CB 3.97Å; L60-A64 VanDerWaalsContact O-CB 3.26Å; L60-A64 WeakPolarHBondContact O-CB 3.23Å; L60-A64 PolarHBondContact O-N 3.37Å; H61-A64 PolarHBondContact O-N 3.47Å; A64-F66 VanDerWaalsContact C-N 3.3Å; A64-F66 PolarHBondContact O-N 2.99Å; A64-L67 PolarHBondContact O-N 3.15Å; A64-E68 WeakPolarHBondContact O-CB 3.16Å; A64-E68 PolarHBondContact O-N 2.84Å; A64-E68 VanDerWaalsContact O-N 3.08Å
65	T	76.3	Confident	75.9	Confident	18 Å²	18	35.5 Å²	35.5	11%	0.11	19%	0.19	C	C	.	.	H	α-helix	trans	-62.5	-37.5	179	-65.3	0	0	0	0	111.7	H61 L62 L63 S69	H61-T65 PolarHBondContact CE1-OG1 3.33Å; H61-T65 PolarHBondContact ND1-OG1 3.37Å; H61-T65 VanDerWaalsContact O-CB 3.31Å; H61-T65 WeakPolarHBondContact O-CB 3.44Å; H61-T65 PolarHBondContact O-N 3.25Å; H61-T65 PolarHBondContact O-OG1 2.98Å; H61-T65 VanDerWaalsContact O-OG1 3.06Å; L62-T65 PolarHBondContact O-N 3.13Å; L63-T65 PolarHBondContact O-N 3.06Å; T65-S69 WeakPolarHBondContact O-CA 3.43Å; T65-S69 WeakPolarHBondContact O-CB 3.46Å; T65-S69 PolarHBondContact O-N 2.99Å; T65-S69 PolarHBondContact O-OG 3.28Å
66	F	78.9	Confident	76.6	Confident	1 Å²	1	37.2 Å²	37.2	0%	0.004	20%	0.197	C	C	.	.	H	α-helix	trans	-72.4	-46.1	-179.5	-163.5	-75.8	0	0	0	112.1	L62 L63 A64 E68 A70 L101 I194 I195 F198	L62-F66 WeakPolarHBondContact O-CB 3.31Å; L62-F66 PolarHBondContact O-N 3.43Å; L63-F66 PolarHBondContact O-N 2.74Å; A64-F66 VanDerWaalsContact C-N 3.3Å; A64-F66 PolarHBondContact O-N 2.99Å; F66-E68 VanDerWaalsContact C-N 3.3Å; F66-E68 PolarHBondContact O-N 3.19Å; F66-A70 HydrophobicContact CD1-CB 4.04Å; F66-A70 HydrophobicContact CE1-CB 4.01Å; F66-A70 HydrophobicContact CG-CB 4.43Å; F66-A70 HydrophobicContact CZ-CB 4.43Å; F66-A70 WeakPolarHBondContact O-CB 3.34Å; F66-A70 PolarHBondContact O-N 3.38Å; F66-A70 VanDerWaalsContact O-N 3.08Å; F66-L101 HydrophobicContact CD2-CD1 3.94Å; F66-L101 HydrophobicContact CD2-CD2 3.86Å; F66-L101 HydrophobicContact CD2-CG 4.05Å; F66-L101 HydrophobicContact CE2-CD1 4.4Å; F66-L101 HydrophobicContact CE2-CD2 3.93Å; F66-L101 HydrophobicContact CG-CD1 4.44Å; F66-I194 WeakPolarHBondContact CE1-O 3.46Å; F66-I195 HydrophobicContact CD1-CB 4.48Å; F66-I195 HydrophobicContact CD1-CG1 4.21Å; F66-I195 HydrophobicContact CD1-CG2 4.49Å; F66-I195 HydrophobicContact CD2-CG2 3.97Å; F66-I195 VanDerWaalsContact CE1-CA 3.47Å; F66-I195 HydrophobicContact CE1-CB 4.29Å; F66-I195 HydrophobicContact CE1-CG1 4.49Å; F66-I195 HydrophobicContact CE1-CG2 4.28Å; F66-I195 HydrophobicContact CE2-CG2 3.7Å; F66-I195 HydrophobicContact CG-CG1 4.36Å; F66-I195 HydrophobicContact CG-CG2 4.33Å; F66-I195 HydrophobicContact CZ-CB 4.28Å; F66-I195 HydrophobicContact CZ-CG2 3.83Å; F66-I195 VanDerWaalsContact CZ-O 3.23Å; F66-I195 WeakPolarHBondContact CZ-O 3.37Å; F66-F198 HydrophobicContact CE1-CB 4.45Å; F66-F198 AromaticContact CE1-CD2 3.3Å; F66-F198 HydrophobicContact CE1-CD2 3.3Å; F66-F198 AromaticContact CE1-CE2 3.74Å; F66-F198 HydrophobicContact CE1-CE2 3.74Å; F66-F198 HydrophobicContact CE1-CG 4.12Å; F66-F198 HydrophobicContact CE2-CB 4.3Å; F66-F198 HydrophobicContact CZ-CB 3.61Å; F66-F198 AromaticContact CZ-CD2 3.35Å; F66-F198 HydrophobicContact CZ-CD2 3.35Å; F66-F198 HydrophobicContact CZ-CE2 4.23Å; F66-F198 AromaticContact CZ-CG 3.76Å; F66-F198 HydrophobicContact CZ-CG 3.76Å
67	L	74.7	Confident	77.1	Confident	72 Å²	72	36.7 Å²	36.7	38%	0.377	19%	0.194	S	C	.	.	H	α-helix	trans	-62	-35.1	177.3	-68.4	179.5	0	0	0	112.8	L63 A64 P71 I194	L63-L67 HydrophobicContact CD1-CD1 3.78Å; L63-L67 HydrophobicContact CD1-CD2 4.33Å; L63-L67 HydrophobicContact CD1-CG 3.81Å; L63-L67 HydrophobicContact CG-CD1 3.94Å; L63-L67 HydrophobicContact CG-CG 4.32Å; L63-L67 WeakPolarHBondContact O-CB 3.23Å; L63-L67 WeakPolarHBondContact O-CG 3.35Å; L63-L67 PolarHBondContact O-N 3.28Å; A64-L67 PolarHBondContact O-N 3.15Å; L67-P71 WeakPolarHBondContact O-CD 3.22Å; L67-P71 VanDerWaalsContact O-CG 3.24Å; L67-P71 WeakPolarHBondContact O-CG 3.5Å; L67-I194 HydrophobicContact CD2-CB 4Å; L67-I194 HydrophobicContact CD2-CD1 3.65Å; L67-I194 HydrophobicContact CD2-CG1 4.41Å; L67-I194 HydrophobicContact CD2-CG2 3.55Å
68	E	80.5	Confident	77.5	Confident	54 Å²	54	37.2 Å²	37.2	25%	0.252	20%	0.198	S	C	.	.	H	α-helix	trans	-83.8	-52.6	178.1	-172.4	174.2	-163.5	0	0	111.8	C14 Q18 A64 F66 Q72	C14-E68 PolarHBondContact SG-OE1 3.27Å; Q18-E68 PolarHBondContact NE2-OE1 3.17Å; Q18-E68 PolarHBondContact NE2-OE2 3.45Å; A64-E68 WeakPolarHBondContact O-CB 3.16Å; A64-E68 PolarHBondContact O-N 2.84Å; A64-E68 VanDerWaalsContact O-N 3.08Å; F66-E68 VanDerWaalsContact C-N 3.3Å; F66-E68 PolarHBondContact O-N 3.19Å; E68-Q72 WeakPolarHBondContact O-CB 3.4Å
69	S	75.2	Confident	78	Confident	34 Å²	34	41 Å²	41	24%	0.238	22%	0.217	C	C	.	.	H	α-helix	trans	-85.8	-31	-165.8	-50.1	0	0	0	0	114.1	T65 L73	T65-S69 WeakPolarHBondContact O-CA 3.43Å; T65-S69 WeakPolarHBondContact O-CB 3.46Å; T65-S69 PolarHBondContact O-N 2.99Å; T65-S69 PolarHBondContact O-OG 3.28Å; S69-L73 WeakPolarHBondContact O-CB 3.49Å; S69-L73 PolarHBondContact O-N 3.47Å
70	A	75.7	Confident	78.3	Confident	1 Å²	1	39.7 Å²	39.7	1%	0.008	21%	0.211	C	C	.	.	H	α-helix	trans	-65.3	-49.3	-179.6	0	0	0	0	0	113.4	F66 L73 V74 L101 F198	F66-A70 HydrophobicContact CD1-CB 4.04Å; F66-A70 HydrophobicContact CE1-CB 4.01Å; F66-A70 HydrophobicContact CG-CB 4.43Å; F66-A70 HydrophobicContact CZ-CB 4.43Å; F66-A70 WeakPolarHBondContact O-CB 3.34Å; F66-A70 PolarHBondContact O-N 3.38Å; F66-A70 VanDerWaalsContact O-N 3.08Å; A70-L73 PolarHBondContact O-N 3.1Å; A70-V74 PolarHBondContact O-N 3.29Å; A70-L101 HydrophobicContact CB-CD1 3.9Å; A70-F198 HydrophobicContact CB-CD1 4.12Å; A70-F198 HydrophobicContact CB-CD2 4.21Å; A70-F198 HydrophobicContact CB-CE1 3.79Å; A70-F198 HydrophobicContact CB-CE2 3.9Å; A70-F198 HydrophobicContact CB-CG 4.33Å; A70-F198 HydrophobicContact CB-CZ 3.68Å
71	P	79.5	Confident	78.5	Confident	68 Å²	68	38.3 Å²	38.3	44%	0.442	20%	0.203	S	C	.	.	H	α-helix	trans	-67.7	-36.7	175.3	26.5	-33.8	0	0	0	112.1	L67 L73 V74 L75	L67-P71 WeakPolarHBondContact O-CD 3.22Å; L67-P71 VanDerWaalsContact O-CG 3.24Å; L67-P71 WeakPolarHBondContact O-CG 3.5Å; P71-L73 VanDerWaalsContact C-N 3.33Å; P71-L73 PolarHBondContact O-N 3.36Å; P71-V74 PolarHBondContact O-N 2.79Å; P71-L75 WeakPolarHBondContact O-CB 3.37Å; P71-L75 PolarHBondContact O-N 3.44Å
72	Q	82.3	Confident	78.3	Confident	111 Å²	111	40 Å²	40	52%	0.519	21%	0.211	S	C	.	.	H	α-helix	trans	-61.2	-41.4	174.8	-179.4	176	-29.5	0	0	111.8	E68 L75 Q76	E68-Q72 WeakPolarHBondContact O-CB 3.4Å; Q72-L75 PolarHBondContact O-N 3.37Å; Q72-Q76 WeakPolarHBondContact O-CB 3.37Å; Q72-Q76 PolarHBondContact O-N 3.23Å
73	L	78.9	Confident	78.1	Confident	2 Å²	2	43.4 Å²	43.4	1%	0.01	23%	0.232	C	C	.	.	H	α-helix	trans	-63.6	-46.5	177.8	177.3	63.7	0	0	0	111.8	S69 A70 P71 L75 Q76 L77 A94 L98 V142	S69-L73 WeakPolarHBondContact O-CB 3.49Å; S69-L73 PolarHBondContact O-N 3.47Å; A70-L73 PolarHBondContact O-N 3.1Å; P71-L73 VanDerWaalsContact C-N 3.33Å; P71-L73 PolarHBondContact O-N 3.36Å; L73-L75 VanDerWaalsContact C-N 3.34Å; L73-L75 PolarHBondContact O-N 3.22Å; L73-Q76 PolarHBondContact O-N 3.1Å; L73-L77 HydrophobicContact CD1-CD1 3.52Å; L73-L77 HydrophobicContact CG-CD1 3.98Å; L73-L77 WeakPolarHBondContact O-CD1 3.46Å; L73-L77 PolarHBondContact O-N 2.67Å; L73-A94 HydrophobicContact CD1-CB 3.95Å; L73-A94 VanDerWaalsContact CD1-O 3.28Å; L73-A94 WeakPolarHBondContact CD1-O 3.41Å; L73-L98 HydrophobicContact CD2-CB 3.94Å; L73-L98 HydrophobicContact CD2-CD1 4.01Å; L73-L98 HydrophobicContact CD2-CG 3.9Å; L73-V142 HydrophobicContact CD2-CG1 3.93Å; L73-V142 HydrophobicContact CD2-CG2 4.15Å; L73-V142 HydrophobicContact CG-CG1 3.86Å
74	V	81.7	Confident	77.6	Confident	7 Å²	7	47.7 Å²	47.7	4%	0.042	25%	0.251	C	S	.	.	H	α-helix	trans	-62.2	-42.9	176.2	173.7	0	0	0	0	111.2	A70 P71 L77 C78 V142 F145 F156 F198	A70-V74 PolarHBondContact O-N 3.29Å; P71-V74 PolarHBondContact O-N 2.79Å; V74-L77 PolarHBondContact O-N 3.48Å; V74-C78 WeakPolarHBondContact O-CB 3.34Å; V74-C78 PolarHBondContact O-N 3.2Å; V74-V142 HydrophobicContact CG2-CG1 4.23Å; V74-V142 HydrophobicContact CG2-CG2 4.48Å; V74-F145 HydrophobicContact CG1-CB 4.06Å; V74-F145 HydrophobicContact CG2-CB 4.27Å; V74-F145 HydrophobicContact CG2-CD2 4.26Å; V74-F156 HydrophobicContact CG1-CE1 4.16Å; V74-F156 HydrophobicContact CG1-CZ 3.8Å; V74-F198 HydrophobicContact CG2-CD1 4.49Å; V74-F198 HydrophobicContact CG2-CE1 3.79Å
75	L	81	Confident	76.9	Confident	109 Å²	109	52.7 Å²	52.7	57%	0.571	28%	0.276	S	S	*	.	H	α-helix	trans	-63.7	-41.5	177.3	-174.3	145.1	0	0	0	111.7	P71 Q72 L73 C78 I79	P71-L75 WeakPolarHBondContact O-CB 3.37Å; P71-L75 PolarHBondContact O-N 3.44Å; Q72-L75 PolarHBondContact O-N 3.37Å; L73-L75 VanDerWaalsContact C-N 3.34Å; L73-L75 PolarHBondContact O-N 3.22Å; L75-C78 PolarHBondContact O-N 3.24Å; L75-I79 HydrophobicContact CD2-CD1 3.66Å; L75-I79 WeakPolarHBondContact O-CG1 3.38Å; L75-I79 PolarHBondContact O-N 2.95Å; L75-I79 VanDerWaalsContact O-N 3.07Å
76	Q	82.8	Confident	76.1	Confident	41 Å²	41	58.2 Å²	58.2	19%	0.192	31%	0.305	C	S	.	.	H	α-helix	trans	-61.9	-47.5	174.7	179.8	175.2	-15.5	0	0	111.9	Q72 L73 C78 I79 I80 Q90 T93	Q72-Q76 WeakPolarHBondContact O-CB 3.37Å; Q72-Q76 PolarHBondContact O-N 3.23Å; L73-Q76 PolarHBondContact O-N 3.1Å; Q76-C78 VanDerWaalsContact C-N 3.31Å; Q76-C78 PolarHBondContact O-N 2.88Å; Q76-I79 PolarHBondContact O-N 3.41Å; Q76-I80 HydrophobicContact CG-CD1 4.08Å; Q76-I80 WeakPolarHBondContact O-CG1 3.24Å; Q76-I80 PolarHBondContact O-N 3.32Å; Q76-I80 VanDerWaalsContact O-N 3.09Å; Q76-Q90 PolarHBondContact NE2-O 3.12Å; Q76-Q90 VanDerWaalsContact NE2-O 3.1Å; Q76-T93 PolarHBondContact NE2-OG1 3.01Å
77	L	79.6	Confident	75.7	Confident	28 Å²	28	63.7 Å²	63.7	15%	0.147	33%	0.33	C	S	.	.	H	α-helix	trans	-62.4	-39.3	175.4	-88.8	83.1	0	0	0	111.8	L73 V74 I79 I80 I81 A94 V142 I143 A146	L73-L77 HydrophobicContact CD1-CD1 3.52Å; L73-L77 HydrophobicContact CG-CD1 3.98Å; L73-L77 WeakPolarHBondContact O-CD1 3.46Å; L73-L77 PolarHBondContact O-N 2.67Å; V74-L77 PolarHBondContact O-N 3.48Å; L77-I79 VanDerWaalsContact C-N 3.33Å; L77-I79 PolarHBondContact O-N 2.95Å; L77-I80 PolarHBondContact O-N 2.99Å; L77-I81 WeakPolarHBondContact O-CD1 3.19Å; L77-I81 VanDerWaalsContact O-CG1 3.28Å; L77-I81 WeakPolarHBondContact O-CG1 3.44Å; L77-I81 PolarHBondContact O-N 3.47Å; L77-A94 HydrophobicContact CD1-CB 3.81Å; L77-V142 HydrophobicContact CD1-CG1 4.11Å; L77-V142 HydrophobicContact CD2-CG1 4.02Å; L77-I143 HydrophobicContact CD2-CG1 4.07Å; L77-A146 HydrophobicContact CB-CB 3.46Å; L77-A146 VanDerWaalsContact CB-CB 3.46Å; L77-A146 HydrophobicContact CD2-CB 4.1Å; L77-A146 HydrophobicContact CG-CB 4.45Å
78	C	80.4	Confident	75.5	Confident	14 Å²	14	63.7 Å²	63.7	10%	0.095	34%	0.34	C	S	.	.	H	α-helix	trans	-60.2	-43	179	-164.8	0	0	0	0	111.6	V74 L75 Q76 I81 Q82	V74-C78 WeakPolarHBondContact O-CB 3.34Å; V74-C78 PolarHBondContact O-N 3.2Å; L75-C78 PolarHBondContact O-N 3.24Å; Q76-C78 VanDerWaalsContact C-N 3.31Å; Q76-C78 PolarHBondContact O-N 2.88Å; C78-I81 PolarHBondContact O-N 3.25Å; C78-Q82 VanDerWaalsContact O-CG 3.31Å; C78-Q82 WeakPolarHBondContact O-CG 3.32Å; C78-Q82 PolarHBondContact O-N 3.29Å; C78-Q82 PolarHBondContact SG-NE2 3.49Å
79	I	80.9	Confident	75.2	Confident	83 Å²	83	65.7 Å²	65.7	43%	0.426	36%	0.356	S	S	.	.	H	α-helix	trans	-63.1	-44.7	174.2	-66.8	167.6	0	0	0	111.3	L75 Q76 L77 I81 Q82 T83	L75-I79 HydrophobicContact CD2-CD1 3.66Å; L75-I79 WeakPolarHBondContact O-CG1 3.38Å; L75-I79 PolarHBondContact O-N 2.95Å; L75-I79 VanDerWaalsContact O-N 3.07Å; Q76-I79 PolarHBondContact O-N 3.41Å; L77-I79 VanDerWaalsContact C-N 3.33Å; L77-I79 PolarHBondContact O-N 2.95Å; I79-I81 VanDerWaalsContact C-N 3.32Å; I79-I81 PolarHBondContact O-N 3Å; I79-Q82 PolarHBondContact O-N 3.44Å; I79-T83 WeakPolarHBondContact O-CB 3.37Å; I79-T83 PolarHBondContact O-N 3.46Å; I79-T83 PolarHBondContact O-OG1 3.4Å
80	I	79.3	Confident	75.1	Confident	17 Å²	17	67.2 Å²	67.2	9%	0.087	36%	0.359	C	S	.	.	H	α-helix	trans	-58.9	-44.7	178.1	-67.7	164.4	0	0	0	110.7	Q76 L77 H84 L86 Q90	Q76-I80 HydrophobicContact CG-CD1 4.08Å; Q76-I80 WeakPolarHBondContact O-CG1 3.24Å; Q76-I80 PolarHBondContact O-N 3.32Å; Q76-I80 VanDerWaalsContact O-N 3.09Å; L77-I80 PolarHBondContact O-N 2.99Å; I80-H84 PolarHBondContact O-N 3.43Å; I80-L86 HydrophobicContact CG2-CD2 3.83Å; I80-Q90 HydrophobicContact CD1-CB 3.87Å; I80-Q90 HydrophobicContact CG1-CB 4.05Å
81	I	74.9	Confident	75.1	Confident	39 Å²	39	68.9 Å²	68.9	20%	0.2	38%	0.377	C	S	.	.	H	α-helix	trans	-64.7	-46.9	179.2	-67.3	158.5	0	0	0	110.9	L77 C78 I79 T83 H84 A146 L147	L77-I81 WeakPolarHBondContact O-CD1 3.19Å; L77-I81 VanDerWaalsContact O-CG1 3.28Å; L77-I81 WeakPolarHBondContact O-CG1 3.44Å; L77-I81 PolarHBondContact O-N 3.47Å; C78-I81 PolarHBondContact O-N 3.25Å; I79-I81 VanDerWaalsContact C-N 3.32Å; I79-I81 PolarHBondContact O-N 3Å; I81-T83 PolarHBondContact O-N 3.41Å; I81-H84 PolarHBondContact O-N 3.34Å; I81-A146 HydrophobicContact CD1-CB 3.56Å; I81-L147 HydrophobicContact CD1-CD2 4.11Å; I81-L147 HydrophobicContact CG2-CD2 4.48Å
82	Q	73.8	Confident	74.8	Confident	85 Å²	85	71.4 Å²	71.4	40%	0.397	38%	0.384	S	S	.	.	H	α-helix	trans	-66.5	-34.1	-179.7	-71.3	174.1	21.1	0	0	113.1	C78 I79 H84	C78-Q82 VanDerWaalsContact O-CG 3.31Å; C78-Q82 WeakPolarHBondContact O-CG 3.32Å; C78-Q82 PolarHBondContact O-N 3.29Å; C78-Q82 PolarHBondContact SG-NE2 3.49Å; I79-Q82 PolarHBondContact O-N 3.44Å; Q82-H84 VanDerWaalsContact C-N 3.28Å; Q82-H84 PolarHBondContact O-N 3.35Å
83	T	72.5	Confident	74.6	Confident	74 Å²	74	69.3 Å²	69.3	45%	0.454	38%	0.379	S	S	.	.	H	α-helix	trans	-78.2	-14.4	-175.8	-49.2	0	0	0	0	112.5	I79 I81 N85	I79-T83 WeakPolarHBondContact O-CB 3.37Å; I79-T83 PolarHBondContact O-N 3.46Å; I79-T83 PolarHBondContact O-OG1 3.4Å; I81-T83 PolarHBondContact O-N 3.41Å; T83-N85 HydrophobicContact CG2-CB 4.32Å; T83-N85 PolarHBondContact O-N 2.69Å; T83-N85 PolarHBondContact O-ND2 3.24Å; T83-N85 VanDerWaalsContact O-ND2 3.09Å
84	H	64.4	Low	74.6	Confident	135 Å²	135	69.5 Å²	69.5	63%	0.625	38%	0.381	S	S	*	.			trans	53.3	-4.5	-175.7	-79.6	-83.4	0	0	0	116.7	I80 I81 Q82 L86	I80-H84 PolarHBondContact O-N 3.43Å; I81-H84 PolarHBondContact O-N 3.34Å; Q82-H84 VanDerWaalsContact C-N 3.28Å; Q82-H84 PolarHBondContact O-N 3.35Å; H84-L86 PolarHBondContact O-N 3.23Å
85	N	61.7	Low	74.5	Confident	114 Å²	114	71.5 Å²	71.5	61%	0.61	40%	0.398	S	S	*	.			trans	-92.3	96.8	175.8	-80.9	-95.8	0	0	0	109.4	T83 Q87	T83-N85 HydrophobicContact CG2-CB 4.32Å; T83-N85 PolarHBondContact O-N 2.69Å; T83-N85 PolarHBondContact O-ND2 3.24Å; T83-N85 VanDerWaalsContact O-ND2 3.09Å; N85-Q87 PolarHBondContact O-N 2.94Å
86	L	59.1	Low	74.4	Confident	134 Å²	134	69.1 Å²	69.1	70%	0.702	39%	0.394	S	S	*	.			trans	-71.1	73.7	172.8	-65.8	175.4	0	0	0	110.9	I80 H84 A88	I80-L86 HydrophobicContact CG2-CD2 3.83Å; H84-L86 PolarHBondContact O-N 3.23Å; L86-A88 PolarHBondContact O-N 3.03Å
87	Q	71.6	Confident	74.4	Confident	115 Å²	115	69.2 Å²	69.2	54%	0.537	40%	0.4	S	S	.	.			trans	-62.5	109.3	162.4	-75.5	-170.4	-12.4	0	0	108	N85 V89 Q90 G91	N85-Q87 PolarHBondContact O-N 2.94Å; Q87-V89 PolarHBondContact O-N 3.13Å; Q87-Q90 HydrophobicContact CB-CB 4.43Å; Q87-Q90 HydrophobicContact CB-CG 3.94Å; Q87-Q90 PolarHBondContact O-N 2.99Å; Q87-G91 PolarHBondContact O-N 3.49Å
88	A	70.6	Confident	74.6	Confident	72 Å²	72	68.5 Å²	68.5	60%	0.595	40%	0.396	S	S	*	.	H	α-helix	trans	-51.1	-33.9	-178.1	0	0	0	0	0	112.6	L86 Q90 G91 M92	L86-A88 PolarHBondContact O-N 3.03Å; A88-Q90 PolarHBondContact O-N 3.05Å; A88-G91 PolarHBondContact O-N 3.32Å; A88-M92 WeakPolarHBondContact O-CB 3.31Å; A88-M92 VanDerWaalsContact O-CG 3.31Å; A88-M92 WeakPolarHBondContact O-CG 2.96Å; A88-M92 PolarHBondContact O-N 3.08Å
89	V	73.8	Confident	74.7	Confident	96 Å²	96	70.8 Å²	70.8	58%	0.582	41%	0.409	S	S	*	.	H	α-helix	trans	-59.4	-41.6	175	-174.6	0	0	0	0	112.7	Q87 M92 T93	Q87-V89 PolarHBondContact O-N 3.13Å; V89-M92 HydrophobicContact CG2-CE 4.31Å; V89-M92 PolarHBondContact O-N 3.01Å; V89-T93 WeakPolarHBondContact O-CG2 3.22Å; V89-T93 PolarHBondContact O-N 3.07Å; V89-T93 PolarHBondContact O-OG1 3.04Å
90	Q	73.2	Confident	74.7	Confident	66 Å²	66	70 Å²	70	31%	0.308	41%	0.412	S	S	.	.	H	α-helix	trans	-71.4	-34.7	178.5	-60.1	-173.9	13	0	0	112.1	Q76 I80 Q87 A88 T93 A94	Q76-Q90 PolarHBondContact NE2-O 3.12Å; Q76-Q90 VanDerWaalsContact NE2-O 3.1Å; I80-Q90 HydrophobicContact CD1-CB 3.87Å; I80-Q90 HydrophobicContact CG1-CB 4.05Å; Q87-Q90 HydrophobicContact CB-CB 4.43Å; Q87-Q90 HydrophobicContact CB-CG 3.94Å; Q87-Q90 PolarHBondContact O-N 2.99Å; A88-Q90 PolarHBondContact O-N 3.05Å; Q90-T93 PolarHBondContact O-OG1 3.17Å; Q90-T93 VanDerWaalsContact O-OG1 3.1Å; Q90-A94 WeakPolarHBondContact O-CB 3.4Å; Q90-A94 PolarHBondContact O-N 3.02Å
91	G	75.3	Confident	74.7	Confident	37 Å²	37	69.4 Å²	69.4	38%	0.381	41%	0.408	S	S	.	.	H	α-helix	trans	-67.1	-42.7	172	0	0	0	0	0	112.4	Q87 A88 A94 A95	Q87-G91 PolarHBondContact O-N 3.49Å; A88-G91 PolarHBondContact O-N 3.32Å; G91-A94 PolarHBondContact O-N 3.5Å; G91-A95 WeakPolarHBondContact O-CB 3.37Å; G91-A95 PolarHBondContact O-N 3.35Å
92	M	72.8	Confident	75.1	Confident	120 Å²	120	67.6 Å²	67.6	59%	0.591	40%	0.399	S	S	*	.	H	α-helix	trans	-64.6	-40.6	177.3	-73.9	-172.9	-62.2	0	0	112.6	A88 V89 A95 A96	A88-M92 WeakPolarHBondContact O-CB 3.31Å; A88-M92 VanDerWaalsContact O-CG 3.31Å; A88-M92 WeakPolarHBondContact O-CG 2.96Å; A88-M92 PolarHBondContact O-N 3.08Å; V89-M92 HydrophobicContact CG2-CE 4.31Å; V89-M92 PolarHBondContact O-N 3.01Å; M92-A95 PolarHBondContact O-N 3.21Å; M92-A96 WeakPolarHBondContact O-CB 3.05Å; M92-A96 PolarHBondContact O-N 3.14Å
93	T	78	Confident	75.5	Confident	67 Å²	67	70.9 Å²	70.9	41%	0.411	41%	0.408	S	S	.	.	H	α-helix	trans	-68.9	-38.6	176.7	52.7	0	0	0	0	112.2	Q76 V89 Q90 A96 S97	Q76-T93 PolarHBondContact NE2-OG1 3.01Å; V89-T93 WeakPolarHBondContact O-CG2 3.22Å; V89-T93 PolarHBondContact O-N 3.07Å; V89-T93 PolarHBondContact O-OG1 3.04Å; Q90-T93 PolarHBondContact O-OG1 3.17Å; Q90-T93 VanDerWaalsContact O-OG1 3.1Å; T93-A96 PolarHBondContact O-N 3.21Å; T93-S97 PolarHBondContact O-N 3.32Å; T93-S97 PolarHBondContact O-OG 3.28Å; T93-S97 VanDerWaalsContact O-OG 3.07Å
94	A	79.9	Confident	75.9	Confident	6 Å²	6	67.7 Å²	67.7	5%	0.05	39%	0.389	C	S	.	.	H	α-helix	trans	-61.7	-45.5	172.1	0	0	0	0	0	111.9	L73 L77 Q90 G91 A96 S97 L98	L73-A94 HydrophobicContact CD1-CB 3.95Å; L73-A94 VanDerWaalsContact CD1-O 3.28Å; L73-A94 WeakPolarHBondContact CD1-O 3.41Å; L77-A94 HydrophobicContact CD1-CB 3.81Å; Q90-A94 WeakPolarHBondContact O-CB 3.4Å; Q90-A94 PolarHBondContact O-N 3.02Å; G91-A94 PolarHBondContact O-N 3.5Å; A94-A96 PolarHBondContact O-N 3.23Å; A94-S97 PolarHBondContact O-N 3.05Å; A94-L98 PolarHBondContact O-N 2.97Å
95	A	80	Confident	76.6	Confident	49 Å²	49	61.2 Å²	61.2	41%	0.405	36%	0.359	S	S	.	.	H	α-helix	trans	-62	-41.9	176.4	0	0	0	0	0	112.4	G91 M92 S97 L98 V99	G91-A95 WeakPolarHBondContact O-CB 3.37Å; G91-A95 PolarHBondContact O-N 3.35Å; M92-A95 PolarHBondContact O-N 3.21Å; A95-S97 PolarHBondContact O-N 2.95Å; A95-L98 PolarHBondContact O-N 3.16Å; A95-V99 WeakPolarHBondContact O-CG2 3.28Å; A95-V99 PolarHBondContact O-N 2.95Å
96	A	77.8	Confident	77.3	Confident	59 Å²	59	55.9 Å²	55.9	49%	0.488	33%	0.33	S	S	.	.	H	α-helix	trans	-62.2	-41	176.1	0	0	0	0	0	112.4	M92 T93 A94 L98 V99 S100	M92-A96 WeakPolarHBondContact O-CB 3.05Å; M92-A96 PolarHBondContact O-N 3.14Å; T93-A96 PolarHBondContact O-N 3.21Å; A94-A96 PolarHBondContact O-N 3.23Å; A96-L98 VanDerWaalsContact C-N 3.34Å; A96-V99 PolarHBondContact O-N 2.96Å; A96-S100 WeakPolarHBondContact O-CB 3.49Å; A96-S100 PolarHBondContact O-N 3.47Å
97	S	82.1	Confident	78	Confident	43 Å²	43	50.7 Å²	50.7	30%	0.301	31%	0.306	S	S	.	.	H	α-helix	trans	-63.2	-39.2	173.9	-61.9	0	0	0	0	112.2	T93 A94 A95 S100 L101	T93-S97 PolarHBondContact O-N 3.32Å; T93-S97 PolarHBondContact O-OG 3.28Å; T93-S97 VanDerWaalsContact O-OG 3.07Å; A94-S97 PolarHBondContact O-N 3.05Å; A95-S97 PolarHBondContact O-N 2.95Å; S97-S100 WeakPolarHBondContact O-CB 3.11Å; S97-S100 PolarHBondContact O-N 2.87Å; S97-L101 PolarHBondContact O-N 2.88Å
98	L	84.6	Confident	78.1	Confident	13 Å²	13	45.4 Å²	45.4	7%	0.068	28%	0.281	C	S	.	.	H	α-helix	trans	-67.8	-42.1	176.6	-152.9	156.8	0	0	0	111.8	L73 A94 A95 A96 S100 L101 A102 F135 I138 A139 V142	L73-L98 HydrophobicContact CD2-CB 3.94Å; L73-L98 HydrophobicContact CD2-CD1 4.01Å; L73-L98 HydrophobicContact CD2-CG 3.9Å; A94-L98 PolarHBondContact O-N 2.97Å; A95-L98 PolarHBondContact O-N 3.16Å; A96-L98 VanDerWaalsContact C-N 3.34Å; L98-S100 VanDerWaalsContact C-N 3.35Å; L98-S100 PolarHBondContact O-N 3.02Å; L98-L101 PolarHBondContact O-N 2.62Å; L98-A102 WeakPolarHBondContact O-CB 3.41Å; L98-A102 PolarHBondContact O-N 3.4Å; L98-F135 HydrophobicContact CD2-CD2 3.61Å; L98-F135 HydrophobicContact CD2-CE2 3.69Å; L98-F135 HydrophobicContact CD2-CG 4.47Å; L98-I138 HydrophobicContact CD2-CB 4.35Å; L98-I138 HydrophobicContact CD2-CG2 4.04Å; L98-I138 HydrophobicContact CG-CG2 4.23Å; L98-A139 HydrophobicContact CD1-CB 4.11Å; L98-A139 HydrophobicContact CD2-CB 4.2Å; L98-V142 HydrophobicContact CD1-CB 4.34Å; L98-V142 HydrophobicContact CD1-CG1 4.32Å
99	V	82.3	Confident	78.3	Confident	63 Å²	63	43.1 Å²	43.1	38%	0.382	26%	0.258	S	S	.	.	H	α-helix	trans	-58.6	-45.2	171.5	166.5	0	0	0	0	111.2	A95 A96 L101 A102 W103 F131 F135	A95-V99 WeakPolarHBondContact O-CG2 3.28Å; A95-V99 PolarHBondContact O-N 2.95Å; A96-V99 PolarHBondContact O-N 2.96Å; V99-L101 PolarHBondContact O-N 3.33Å; V99-A102 PolarHBondContact O-N 3.03Å; V99-W103 VanDerWaalsContact O-CB 3.29Å; V99-W103 WeakPolarHBondContact O-CB 3.38Å; V99-W103 PolarHBondContact O-N 3.21Å; V99-F131 HydrophobicContact CG1-CE2 4.44Å; V99-F131 HydrophobicContact CG1-CZ 4.11Å; V99-F135 HydrophobicContact CG2-CD2 4.11Å; V99-F135 HydrophobicContact CG2-CE2 3.59Å; V99-F135 HydrophobicContact CG2-CZ 4.43Å
100	S	80.6	Confident	78.3	Confident	67 Å²	67	41.7 Å²	41.7	47%	0.469	24%	0.244	S	C	.	.	H	α-helix	trans	-59.4	-46	177.8	-171.8	0	0	0	0	111.9	A96 S97 L98 W103 A104	A96-S100 WeakPolarHBondContact O-CB 3.49Å; A96-S100 PolarHBondContact O-N 3.47Å; S97-S100 WeakPolarHBondContact O-CB 3.11Å; S97-S100 PolarHBondContact O-N 2.87Å; L98-S100 VanDerWaalsContact C-N 3.35Å; L98-S100 PolarHBondContact O-N 3.02Å; S100-W103 PolarHBondContact O-N 3.43Å; S100-A104 PolarHBondContact O-N 3.1Å
101	L	80.1	Confident	78.1	Confident	4 Å²	4	38.7 Å²	38.7	2%	0.021	23%	0.23	C	C	.	.	H	α-helix	trans	-67.1	-42.2	179.1	-170.2	153	0	0	0	112.2	F66 A70 S97 L98 V99 W103 A104 L105 I138	F66-L101 HydrophobicContact CD2-CD1 3.94Å; F66-L101 HydrophobicContact CD2-CD2 3.86Å; F66-L101 HydrophobicContact CD2-CG 4.05Å; F66-L101 HydrophobicContact CE2-CD1 4.4Å; F66-L101 HydrophobicContact CE2-CD2 3.93Å; F66-L101 HydrophobicContact CG-CD1 4.44Å; A70-L101 HydrophobicContact CB-CD1 3.9Å; S97-L101 PolarHBondContact O-N 2.88Å; L98-L101 PolarHBondContact O-N 2.62Å; V99-L101 PolarHBondContact O-N 3.33Å; L101-W103 VanDerWaalsContact C-N 3.32Å; L101-W103 PolarHBondContact O-N 2.93Å; L101-A104 PolarHBondContact O-N 3.23Å; L101-L105 HydrophobicContact CD2-CD1 3.85Å; L101-L105 PolarHBondContact O-N 3.03Å; L101-L105 VanDerWaalsContact O-N 3.09Å; L101-I138 HydrophobicContact CD2-CD1 3.88Å; L101-I138 HydrophobicContact CD2-CG2 4.26Å
102	A	84	Confident	77.8	Confident	0 Å²	0	37.5 Å²	37.5	0%	0	22%	0.215	C	C	.	.	H	α-helix	trans	-64.1	-36.4	173.9	0	0	0	0	0	112.2	L98 V99 L105 A106 F131 F135	L98-A102 WeakPolarHBondContact O-CB 3.41Å; L98-A102 PolarHBondContact O-N 3.4Å; V99-A102 PolarHBondContact O-N 3.03Å; A102-L105 PolarHBondContact O-N 2.96Å; A102-A106 WeakPolarHBondContact O-CB 3.44Å; A102-A106 PolarHBondContact O-N 2.85Å; A102-F131 HydrophobicContact CB-CD2 4.25Å; A102-F131 HydrophobicContact CB-CE2 3.87Å; A102-F135 HydrophobicContact CB-CB 3.99Å; A102-F135 HydrophobicContact CB-CD2 4.29Å
103	W	82.1	Confident	77.6	Confident	154 Å²	154	33.7 Å²	33.7	58%	0.583	19%	0.194	S	C	*	.	H	α-helix	trans	-69	-39.5	174.7	-174.8	-97.4	0	0	0	112.3	V99 S100 L101 L105 A106 S107 F131	V99-W103 VanDerWaalsContact O-CB 3.29Å; V99-W103 WeakPolarHBondContact O-CB 3.38Å; V99-W103 PolarHBondContact O-N 3.21Å; S100-W103 PolarHBondContact O-N 3.43Å; L101-W103 VanDerWaalsContact C-N 3.32Å; L101-W103 PolarHBondContact O-N 2.93Å; W103-L105 PolarHBondContact O-N 3.49Å; W103-A106 PolarHBondContact O-N 3.29Å; W103-S107 VanDerWaalsContact O-CB 3.24Å; W103-S107 WeakPolarHBondContact O-CB 3.3Å; W103-S107 PolarHBondContact O-N 3.35Å; W103-S107 PolarHBondContact O-OG 2.92Å; W103-F131 HydrophobicContact CB-CD2 4.44Å; W103-F131 HydrophobicContact CB-CE2 4.15Å; W103-F131 AromaticContact CE3-CD2 3.96Å; W103-F131 HydrophobicContact CE3-CD2 3.96Å; W103-F131 HydrophobicContact CE3-CE2 4.25Å
104	A	79.3	Confident	77	Confident	7 Å²	7	33.3 Å²	33.3	6%	0.058	19%	0.187	C	C	.	.	H	α-helix	trans	-59.9	-44.3	173.4	0	0	0	0	0	111.5	L62 S100 L101 S107 Y108	L62-A104 HydrophobicContact CD1-CB 3.93Å; S100-A104 PolarHBondContact O-N 3.1Å; L101-A104 PolarHBondContact O-N 3.23Å; A104-S107 WeakPolarHBondContact CA-OG 3.43Å; A104-S107 PolarHBondContact O-OG 3.47Å; A104-S107 VanDerWaalsContact O-OG 3.11Å; A104-Y108 WeakPolarHBondContact O-CB 3.29Å; A104-Y108 PolarHBondContact O-N 2.88Å
105	L	79.6	Confident	76	Confident	0 Å²	0	33.4 Å²	33.4	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-62.8	-49.2	174.9	-77.7	165.1	0	0	0	112.6	L62 L101 A102 W103 Y108 Q109 I138 F201	L62-L105 HydrophobicContact CD1-CB 4.48Å; L62-L105 HydrophobicContact CD1-CD2 3.69Å; L62-L105 HydrophobicContact CD1-CG 3.69Å; L62-L105 HydrophobicContact CD2-CD2 3.82Å; L62-L105 HydrophobicContact CG-CD2 4.35Å; L101-L105 HydrophobicContact CD2-CD1 3.85Å; L101-L105 PolarHBondContact O-N 3.03Å; L101-L105 VanDerWaalsContact O-N 3.09Å; A102-L105 PolarHBondContact O-N 2.96Å; W103-L105 PolarHBondContact O-N 3.49Å; L105-Y108 PolarHBondContact O-N 3.03Å; L105-Q109 WeakPolarHBondContact O-CG 3.37Å; L105-Q109 PolarHBondContact O-N 3.41Å; L105-I138 HydrophobicContact CD1-CD1 3.36Å; L105-F201 HydrophobicContact CD2-CD2 4.09Å
106	A	76.1	Confident	75.1	Confident	1 Å²	1	33.7 Å²	33.7	1%	0.008	18%	0.178	C	C	.	.	H	α-helix	trans	-65.5	-39.8	-179.1	0	0	0	0	0	112.4	A102 W103 K110 F131	A102-A106 WeakPolarHBondContact O-CB 3.44Å; A102-A106 PolarHBondContact O-N 2.85Å; W103-A106 PolarHBondContact O-N 3.29Å; A106-K110 WeakPolarHBondContact O-CB 3.45Å; A106-K110 PolarHBondContact O-N 2.9Å; A106-F131 HydrophobicContact CB-CB 4.18Å
107	S	73.7	Confident	73.8	Confident	26 Å²	26	35 Å²	35	18%	0.182	18%	0.177	C	C	.	.	H	α-helix	trans	-70.1	-38.3	177.8	58.6	0	0	0	0	112.7	W103 A104 K110 A111	W103-S107 VanDerWaalsContact O-CB 3.24Å; W103-S107 WeakPolarHBondContact O-CB 3.3Å; W103-S107 PolarHBondContact O-N 3.35Å; W103-S107 PolarHBondContact O-OG 2.92Å; A104-S107 WeakPolarHBondContact CA-OG 3.43Å; A104-S107 PolarHBondContact O-OG 3.47Å; A104-S107 VanDerWaalsContact O-OG 3.11Å; S107-K110 PolarHBondContact O-N 3.3Å; S107-A111 WeakPolarHBondContact O-CB 3.15Å; S107-A111 PolarHBondContact O-N 3.39Å
108	Y	74.4	Confident	72.2	Confident	3 Å²	3	36.5 Å²	36.5	1%	0.012	18%	0.182	C	C	.	.	H	α-helix	trans	-63.7	-48.3	171.5	171.7	-103	0	0	0	112.4	M59 L62 A104 L105 K110 A111 L112 F201	M59-Y108 HydrophobicContact CB-CD2 4.09Å; M59-Y108 HydrophobicContact CB-CE2 3.5Å; M59-Y108 HydrophobicContact CG-CE2 3.71Å; L62-Y108 HydrophobicContact CD2-CD1 3.77Å; L62-Y108 HydrophobicContact CD2-CG 3.83Å; A104-Y108 WeakPolarHBondContact O-CB 3.29Å; A104-Y108 PolarHBondContact O-N 2.88Å; L105-Y108 PolarHBondContact O-N 3.03Å; Y108-K110 PolarHBondContact O-N 3.38Å; Y108-A111 WeakPolarHBondContact O-CA 3.26Å; Y108-A111 WeakPolarHBondContact O-CB 3.15Å; Y108-A111 PolarHBondContact O-N 3.17Å; Y108-L112 HydrophobicContact CD1-CD1 4.2Å; Y108-L112 HydrophobicContact CD1-CG 4.46Å; Y108-L112 HydrophobicContact CE1-CD1 3.39Å; Y108-L112 HydrophobicContact CE1-CG 3.87Å; Y108-L112 HydrophobicContact CE2-CD1 4.34Å; Y108-L112 HydrophobicContact CE2-CD2 4.11Å; Y108-L112 HydrophobicContact CE2-CG 3.94Å; Y108-L112 PolarHBondContact O-N 3.46Å; Y108-F201 HydrophobicContact CD1-CD2 4.48Å; Y108-F201 AromaticContact CD1-CE2 3.45Å; Y108-F201 HydrophobicContact CD1-CE2 3.45Å; Y108-F201 VanDerWaalsContact CD1-CE2 3.45Å; Y108-F201 AromaticContact CD1-CZ 3.99Å; Y108-F201 HydrophobicContact CD1-CZ 3.99Å; Y108-F201 HydrophobicContact CE1-CD2 4.35Å; Y108-F201 HydrophobicContact CE1-CE1 4.47Å; Y108-F201 AromaticContact CE1-CE2 3.18Å; Y108-F201 HydrophobicContact CE1-CE2 3.18Å; Y108-F201 AromaticContact CE1-CZ 3.28Å; Y108-F201 HydrophobicContact CE1-CZ 3.28Å; Y108-F201 HydrophobicContact CG-CE2 4.49Å; Y108-F201 AromaticContact CZ-CZ 3.76Å
109	Q	74.2	Confident	70.5	Confident	24 Å²	24	40.4 Å²	40.4	11%	0.112	20%	0.198	C	C	.	.	H	α-helix	trans	-64.6	-29.3	178.1	-70.4	-177.9	-6	0	0	112.2	L105 R113 H134	L105-Q109 WeakPolarHBondContact O-CG 3.37Å; L105-Q109 PolarHBondContact O-N 3.41Å; Q109-R113 PolarHBondContact O-N 3.43Å; Q109-H134 PolarHBondContact NE2-NE2 3.01Å; Q109-H134 PolarHBondContact OE1-NE2 3.48Å
110	K	74.2	Confident	69	Low	67 Å²	67	46.3 Å²	46.3	29%	0.291	22%	0.219	S	C	.	.	H	α-helix	trans	-66.3	-48.1	167	-174.7	-178.5	178.2	-175.3	0	111.3	A106 S107 Y108 L112 R113 E114 V127	A106-K110 WeakPolarHBondContact O-CB 3.45Å; A106-K110 PolarHBondContact O-N 2.9Å; S107-K110 PolarHBondContact O-N 3.3Å; Y108-K110 PolarHBondContact O-N 3.38Å; K110-L112 VanDerWaalsContact C-N 3.34Å; K110-L112 PolarHBondContact O-N 3.37Å; K110-R113 PolarHBondContact O-N 3.44Å; K110-R113 VanDerWaalsContact O-N 3.08Å; K110-E114 WeakPolarHBondContact CE-OE1 3.43Å; K110-E114 HydrophobicContact CG-CG 3.96Å; K110-E114 VanDerWaalsContact O-CG 3.3Å; K110-E114 WeakPolarHBondContact O-CG 3.37Å; K110-E114 PolarHBondContact O-N 3.32Å; K110-V127 HydrophobicContact CD-CG2 4.1Å
111	A	69.8	Low	67.7	Low	2 Å²	2	48.6 Å²	48.6	2%	0.017	23%	0.232	C	C	.	.	H	α-helix	trans	-58	-43.8	-179.9	0	0	0	0	0	112.3	F54 A55 S107 Y108 R113 E114 S115	F54-A111 HydrophobicContact CD1-CB 3.77Å; F54-A111 HydrophobicContact CE1-CB 3.74Å; A55-A111 HydrophobicContact CB-CB 4.34Å; S107-A111 WeakPolarHBondContact O-CB 3.15Å; S107-A111 PolarHBondContact O-N 3.39Å; Y108-A111 WeakPolarHBondContact O-CA 3.26Å; Y108-A111 WeakPolarHBondContact O-CB 3.15Å; Y108-A111 PolarHBondContact O-N 3.17Å; A111-R113 PolarHBondContact O-N 3.41Å; A111-E114 PolarHBondContact O-N 2.86Å; A111-S115 WeakPolarHBondContact O-CB 3.5Å; A111-S115 PolarHBondContact O-N 3.31Å
112	L	68.9	Low	66.7	Low	12 Å²	12	49.3 Å²	49.3	6%	0.063	24%	0.236	C	C	.	.	H	α-helix	trans	-56.1	-48.9	171.7	-76	-176.6	0	0	0	111.8	Y108 K110 S115 A364	Y108-L112 HydrophobicContact CD1-CD1 4.2Å; Y108-L112 HydrophobicContact CD1-CG 4.46Å; Y108-L112 HydrophobicContact CE1-CD1 3.39Å; Y108-L112 HydrophobicContact CE1-CG 3.87Å; Y108-L112 HydrophobicContact CE2-CD1 4.34Å; Y108-L112 HydrophobicContact CE2-CD2 4.11Å; Y108-L112 HydrophobicContact CE2-CG 3.94Å; Y108-L112 PolarHBondContact O-N 3.46Å; K110-L112 VanDerWaalsContact C-N 3.34Å; K110-L112 PolarHBondContact O-N 3.37Å; L112-S115 WeakPolarHBondContact O-CB 3.3Å; L112-S115 PolarHBondContact O-N 3.07Å; L112-S115 PolarHBondContact O-OG 3.42Å; L112-A364 HydrophobicContact CD1-CB 4.31Å; L112-A364 HydrophobicContact CD2-CB 4.41Å
113	R	68.1	Low	65.9	Low	40 Å²	40	51.2 Å²	51.2	15%	0.151	26%	0.255	C	S	.	.	H	α-helix	trans	-72.6	-30.6	-176	-176	159.7	158.8	-163.4	0.3	113.6	Q109 K110 A111 S115 R116 I122 Y264	Q109-R113 PolarHBondContact O-N 3.43Å; K110-R113 PolarHBondContact O-N 3.44Å; K110-R113 VanDerWaalsContact O-N 3.08Å; A111-R113 PolarHBondContact O-N 3.41Å; R113-S115 VanDerWaalsContact C-N 3.32Å; R113-R116 PolarHBondContact O-N 3.35Å; R113-I122 HydrophobicContact CB-CD1 4.22Å; R113-I122 HydrophobicContact CG-CD1 3.9Å; R113-Y264 PolarHBondContact NH1-OH 3.09Å
114	E	65.1	Low	65.6	Low	59 Å²	59	53 Å²	53	28%	0.276	26%	0.263	S	S	.	.	H	α-helix	trans	-72	-27	170.7	-62.7	-76.2	152.5	0	0	111.6	K110 A111 R116	K110-E114 WeakPolarHBondContact CE-OE1 3.43Å; K110-E114 HydrophobicContact CG-CG 3.96Å; K110-E114 VanDerWaalsContact O-CG 3.3Å; K110-E114 WeakPolarHBondContact O-CG 3.37Å; K110-E114 PolarHBondContact O-N 3.32Å; A111-E114 PolarHBondContact O-N 2.86Å; E114-R116 PolarHBondContact O-N 2.95Å
115	S	58.7	Low	65.5	Low	8 Å²	8	58.1 Å²	58.1	6%	0.056	29%	0.289	C	S	.	.	T	Hydrogen-bonded Turn	trans	-72.7	0.7	173	80.8	0	0	0	0	114.4	A111 L112 R113	A111-S115 WeakPolarHBondContact O-CB 3.5Å; A111-S115 PolarHBondContact O-N 3.31Å; L112-S115 WeakPolarHBondContact O-CB 3.3Å; L112-S115 PolarHBondContact O-N 3.07Å; L112-S115 PolarHBondContact O-OG 3.42Å; R113-S115 VanDerWaalsContact C-N 3.32Å
116	R	62.1	Low	65.4	Low	55 Å²	55	58.1 Å²	58.1	21%	0.208	29%	0.289	C	S	.	.			trans	-120.1	104.5	-175.6	-175.6	177.5	171.7	174.5	2	111.3	R113 E114 D118 E205	R113-R116 PolarHBondContact O-N 3.35Å; E114-R116 PolarHBondContact O-N 2.95Å; R116-D118 HydrophobicContact CG-CB 4.33Å; R116-D118 IonicContact CZ-OD2 3.84Å; R116-D118 IonicContact NE-OD2 3.9Å; R116-D118 PolarHBondContact NE-OD2 3.36Å; R116-D118 IonicContact NH2-OD2 3.24Å; R116-D118 PolarHBondContact NH2-OD2 2.69Å; R116-D118 PolarHBondContact O-N 3.14Å; R116-E205 VanDerWaalsContact CD-OE2 3.22Å; R116-E205 WeakPolarHBondContact CD-OE2 3.42Å; R116-E205 IonicContact CZ-OE2 3.07Å; R116-E205 IonicContact NE-OE2 3.91Å; R116-E205 IonicContact NH1-OE2 2.77Å; R116-E205 PolarHBondContact NH1-OE2 2.8Å
117	D	49.8	Very low	65.6	Low	86 Å²	86	59 Å²	59	46%	0.46	29%	0.294	S	S	.	.	T	Hydrogen-bonded Turn	trans	-56	-13.7	-176	-104	-40.9	0	0	0	116.4	W48 K119 R375	W48-D117 HydrophobicContact CH2-CB 4.38Å; W48-D117 VanDerWaalsContact CZ2-OD1 3.24Å; W48-D117 WeakPolarHBondContact CZ2-OD1 3.43Å; W48-D117 WeakPolarHBondContact CZ2-OD2 3.29Å; D117-K119 VanDerWaalsContact C-N 3.35Å; D117-K119 PolarHBondContact O-N 3.13Å; D117-R375 IonicContact OD2-CZ 3.31Å; D117-R375 IonicContact OD2-NH1 3.06Å; D117-R375 PolarHBondContact OD2-NH1 2.82Å; D117-R375 IonicContact OD2-NH2 3.8Å; D117-R375 PolarHBondContact OD2-NH2 3.14Å
118	D	48.8	Very low	66	Low	75 Å²	75	62.5 Å²	62.5	40%	0.401	31%	0.31	S	S	.	.	T	Hydrogen-bonded Turn	trans	-73.8	-12.1	-167.8	-67	-46.9	0	0	0	116.3	R116 R359	R116-D118 HydrophobicContact CG-CB 4.33Å; R116-D118 IonicContact CZ-OD2 3.84Å; R116-D118 IonicContact NE-OD2 3.9Å; R116-D118 PolarHBondContact NE-OD2 3.36Å; R116-D118 IonicContact NH2-OD2 3.24Å; R116-D118 PolarHBondContact NH2-OD2 2.69Å; R116-D118 PolarHBondContact O-N 3.14Å; D118-R359 IonicContact OD1-CZ 2.94Å; D118-R359 IonicContact OD1-NH1 2.72Å; D118-R359 PolarHBondContact OD1-NH1 3.34Å; D118-R359 IonicContact OD1-NH2 3.38Å; D118-R359 IonicContact OD2-CZ 2.67Å; D118-R359 IonicContact OD2-NE 2.88Å; D118-R359 IonicContact OD2-NH1 3.66Å; D118-R359 PolarHBondContact OD2-NH1 3.12Å; D118-R359 IonicContact OD2-NH2 3.93Å
119	K	47.9	Very low	66.5	Low	96 Å²	96	62.9 Å²	62.9	42%	0.417	31%	0.312	S	S	.	.	S	Bend	trans	-132.7	141.2	-168.1	-72.4	-176	179.3	174.7	0	113.2	D117	D117-K119 VanDerWaalsContact C-N 3.35Å; D117-K119 PolarHBondContact O-N 3.13Å
120	K	52	Low	66.8	Low	187 Å²	187	62 Å²	62	81%	0.813	31%	0.308	S	S	*	.	P	Polyproline II helix	trans	-48.6	142.2	171.1	-66.2	-177.1	178.7	-177.1	0	110.3	I122	K120-I122 PolarHBondContact O-N 3.1Å
121	P	52	Low	67.3	Low	114 Å²	114	60.8 Å²	60.8	74%	0.74	30%	0.303	S	S	*	.	P	Polyproline II helix	trans	-53.9	139.1	-176.4	21.8	-34	0	0	0	111	G123	P121-G123 PolarHBondContact O-N 2.71Å
122	I	59.8	Low	68.2	Low	20 Å²	20	62 Å²	62	10%	0.103	31%	0.31	C	S	.	.	P	Polyproline II helix	trans	-63.1	120.8	179.1	-74.4	174	0	0	0	109.1	R113 K120 A126 V127	R113-I122 HydrophobicContact CB-CD1 4.22Å; R113-I122 HydrophobicContact CG-CD1 3.9Å; K120-I122 PolarHBondContact O-N 3.1Å; I122-A126 HydrophobicContact CG2-CB 3.66Å; I122-V127 HydrophobicContact CG2-CG2 3.56Å
123	G	66.6	Low	69.1	Low	40 Å²	40	61.6 Å²	61.6	41%	0.412	31%	0.308	S	S	.	.	P	Polyproline II helix	trans	-62.9	141.2	166.8	0	0	0	0	0	110.5	P121 L125 A126	P121-G123 PolarHBondContact O-N 2.71Å; G123-L125 PolarHBondContact O-N 3.16Å; G123-A126 PolarHBondContact O-N 2.87Å
124	Y	75.8	Confident	70.1	Confident	192 Å²	192	59.7 Å²	59.7	75%	0.753	30%	0.301	S	S	*	.	H	α-helix	trans	-47.9	-33.9	-179.2	-74	-85.6	0	0	0	113.8	A126 V127 I128	Y124-A126 VanDerWaalsContact C-N 3.32Å; Y124-A126 PolarHBondContact O-N 2.99Å; Y124-V127 PolarHBondContact O-N 3.49Å; Y124-I128 WeakPolarHBondContact O-CG1 3.21Å; Y124-I128 PolarHBondContact O-N 2.95Å; Y124-I128 VanDerWaalsContact O-N 3.12Å
125	L	78.3	Confident	71.2	Confident	113 Å²	113	59.3 Å²	59.3	59%	0.592	30%	0.299	S	S	*	.	H	α-helix	trans	-55.7	-40.5	174.8	-170.7	70.4	0	0	0	113.3	G123 V127 I128 I129 F268	G123-L125 PolarHBondContact O-N 3.16Å; L125-V127 PolarHBondContact O-N 3.01Å; L125-I128 PolarHBondContact O-N 2.93Å; L125-I129 HydrophobicContact CD1-CD1 4.36Å; L125-I129 HydrophobicContact CD2-CD1 4.33Å; L125-I129 HydrophobicContact CG-CD1 3.83Å; L125-I129 WeakPolarHBondContact O-CB 3.38Å; L125-I129 VanDerWaalsContact O-CG1 3.27Å; L125-I129 WeakPolarHBondContact O-CG1 3.37Å; L125-I129 PolarHBondContact O-N 3.44Å; L125-F268 HydrophobicContact CB-CZ 4.46Å; L125-F268 HydrophobicContact CD2-CZ 4.36Å; L125-F268 HydrophobicContact CG-CZ 4.49Å
126	A	77.9	Confident	72.8	Confident	0 Å²	0	61.8 Å²	61.8	0%	0	31%	0.308	C	S	.	.	H	α-helix	trans	-67.9	-36.7	179.6	0	0	0	0	0	111.8	I122 G123 Y124 I129 Q130 Y264 F268	I122-A126 HydrophobicContact CG2-CB 3.66Å; G123-A126 PolarHBondContact O-N 2.87Å; Y124-A126 VanDerWaalsContact C-N 3.32Å; Y124-A126 PolarHBondContact O-N 2.99Å; A126-I129 PolarHBondContact O-N 3.19Å; A126-Q130 WeakPolarHBondContact O-CB 3.39Å; A126-Q130 PolarHBondContact O-N 3.09Å; A126-Y264 HydrophobicContact CB-CE2 4.36Å; A126-F268 HydrophobicContact CB-CD1 3.61Å; A126-F268 HydrophobicContact CB-CD2 3.97Å; A126-F268 HydrophobicContact CB-CE1 3.37Å; A126-F268 HydrophobicContact CB-CE2 3.76Å; A126-F268 HydrophobicContact CB-CG 3.9Å; A126-F268 HydrophobicContact CB-CZ 3.45Å; A126-F268 VanDerWaalsContact CB-CZ 3.45Å
127	V	78.5	Confident	74.1	Confident	20 Å²	20	59.5 Å²	59.5	12%	0.121	30%	0.301	C	S	.	.	H	α-helix	trans	-63.6	-43.3	175.2	-171.4	0	0	0	0	110.4	K110 I122 Y124 L125 Q130 F131	K110-V127 HydrophobicContact CD-CG2 4.1Å; I122-V127 HydrophobicContact CG2-CG2 3.56Å; Y124-V127 PolarHBondContact O-N 3.49Å; L125-V127 PolarHBondContact O-N 3.01Å; V127-Q130 PolarHBondContact O-N 2.81Å; V127-F131 WeakPolarHBondContact O-CB 3.49Å; V127-F131 PolarHBondContact O-N 2.9Å
128	I	82.6	Confident	76.1	Confident	100 Å²	100	55.5 Å²	55.5	51%	0.513	28%	0.279	S	S	.	.	H	α-helix	trans	-64	-47.9	177.8	-65.2	166.5	0	0	0	110.6	Y124 L125 Q130 F131 C132	Y124-I128 WeakPolarHBondContact O-CG1 3.21Å; Y124-I128 PolarHBondContact O-N 2.95Å; Y124-I128 VanDerWaalsContact O-N 3.12Å; L125-I128 PolarHBondContact O-N 2.93Å; I128-Q130 VanDerWaalsContact C-N 3.33Å; I128-Q130 PolarHBondContact O-N 2.83Å; I128-F131 PolarHBondContact O-N 2.72Å; I128-C132 WeakPolarHBondContact O-CB 3.4Å; I128-C132 PolarHBondContact O-N 2.81Å; I128-C132 PolarHBondContact O-SG 3.2Å
129	I	84.4	Confident	78	Confident	11 Å²	11	52.5 Å²	52.5	6%	0.056	27%	0.265	C	S	.	.	H	α-helix	trans	-61	-42.6	178.4	-70.1	169.4	0	0	0	111.2	L125 A126 C132 W133 F260 M263 Y264 F268	L125-I129 HydrophobicContact CD1-CD1 4.36Å; L125-I129 HydrophobicContact CD2-CD1 4.33Å; L125-I129 HydrophobicContact CG-CD1 3.83Å; L125-I129 WeakPolarHBondContact O-CB 3.38Å; L125-I129 VanDerWaalsContact O-CG1 3.27Å; L125-I129 WeakPolarHBondContact O-CG1 3.37Å; L125-I129 PolarHBondContact O-N 3.44Å; A126-I129 PolarHBondContact O-N 3.19Å; I129-C132 PolarHBondContact O-N 2.76Å; I129-W133 WeakPolarHBondContact O-CB 3.24Å; I129-W133 PolarHBondContact O-N 2.81Å; I129-F260 HydrophobicContact CG2-CD1 4.29Å; I129-F260 WeakPolarHBondContact CG2-O 3.04Å; I129-M263 HydrophobicContact CD1-CE 3.81Å; I129-M263 HydrophobicContact CD1-CG 4.39Å; I129-M263 HydrophobicContact CD1-SD 4.28Å; I129-M263 HydrophobicContact CG1-CE 3.76Å; I129-M263 HydrophobicContact CG2-CE 4Å; I129-Y264 HydrophobicContact CG2-CD2 4.48Å; I129-F268 HydrophobicContact CD1-CE2 3.93Å
130	Q	82.1	Confident	80.2	Confident	4 Å²	4	47.9 Å²	47.9	2%	0.019	25%	0.245	C	C	.	.	H	α-helix	trans	-66.5	-40.8	178.3	-175.6	172.7	3.6	0	0	112.1	A126 V127 I128 H134 Y264	A126-Q130 WeakPolarHBondContact O-CB 3.39Å; A126-Q130 PolarHBondContact O-N 3.09Å; V127-Q130 PolarHBondContact O-N 2.81Å; I128-Q130 VanDerWaalsContact C-N 3.33Å; I128-Q130 PolarHBondContact O-N 2.83Å; Q130-H134 PolarHBondContact O-CD2 3.12Å; Q130-H134 PolarHBondContact O-N 3.18Å; Q130-Y264 HydrophobicContact CB-CD2 4.2Å; Q130-Y264 HydrophobicContact CB-CE2 4.1Å; Q130-Y264 HydrophobicContact CG-CE2 4.4Å
131	F	84.9	Confident	82.1	Confident	42 Å²	42	39 Å²	39	18%	0.184	21%	0.206	C	C	.	.	H	α-helix	trans	-61.5	-48.1	171.5	171	-96.8	0	0	0	111.7	V99 A102 W103 A106 V127 I128 W133 H134 F135	V99-F131 HydrophobicContact CG1-CE2 4.44Å; V99-F131 HydrophobicContact CG1-CZ 4.11Å; A102-F131 HydrophobicContact CB-CD2 4.25Å; A102-F131 HydrophobicContact CB-CE2 3.87Å; W103-F131 HydrophobicContact CB-CD2 4.44Å; W103-F131 HydrophobicContact CB-CE2 4.15Å; W103-F131 AromaticContact CE3-CD2 3.96Å; W103-F131 HydrophobicContact CE3-CD2 3.96Å; W103-F131 HydrophobicContact CE3-CE2 4.25Å; A106-F131 HydrophobicContact CB-CB 4.18Å; V127-F131 WeakPolarHBondContact O-CB 3.49Å; V127-F131 PolarHBondContact O-N 2.9Å; I128-F131 PolarHBondContact O-N 2.72Å; F131-W133 PolarHBondContact O-N 3.38Å; F131-H134 PolarHBondContact O-N 3.45Å; F131-F135 HydrophobicContact CZ-CB 4.48Å; F131-F135 HydrophobicContact CZ-CD2 4.48Å; F131-F135 VanDerWaalsContact O-CB 3.26Å; F131-F135 WeakPolarHBondContact O-CB 3.49Å; F131-F135 PolarHBondContact O-N 2.96Å
132	C	88.1	Confident	84	Confident	27 Å²	27	33.7 Å²	33.7	18%	0.182	17%	0.172	C	C	.	.	H	α-helix	trans	-59.8	-46.2	177.8	-70.8	0	0	0	0	112.1	I128 I129 H134 F135 F136 F260	I128-C132 WeakPolarHBondContact O-CB 3.4Å; I128-C132 PolarHBondContact O-N 2.81Å; I128-C132 PolarHBondContact O-SG 3.2Å; I129-C132 PolarHBondContact O-N 2.76Å; C132-H134 PolarHBondContact O-N 2.92Å; C132-F135 PolarHBondContact O-N 2.91Å; C132-F136 HydrophobicContact CB-CD2 4.35Å; C132-F136 HydrophobicContact CB-CE2 4.37Å; C132-F136 WeakPolarHBondContact O-CB 3.34Å; C132-F136 WeakPolarHBondContact O-CD2 3.42Å; C132-F136 PolarHBondContact O-N 3.45Å; C132-F260 HydrophobicContact CB-CD1 3.93Å; C132-F260 HydrophobicContact CB-CD2 3.95Å; C132-F260 HydrophobicContact CB-CE1 4.04Å; C132-F260 HydrophobicContact CB-CE2 4.04Å; C132-F260 HydrophobicContact CB-CG 3.92Å; C132-F260 HydrophobicContact CB-CZ 4.1Å
133	W	88.6	Confident	85.4	Confident	4 Å²	4	34.9 Å²	34.9	2%	0.015	18%	0.177	C	C	.	.	H	α-helix	trans	-52.3	-56.9	175.5	167.8	22.3	0	0	0	111.2	I129 F131 F136 T137 Y216 G257 F260 M261 Y264 Y265	I129-W133 WeakPolarHBondContact O-CB 3.24Å; I129-W133 PolarHBondContact O-N 2.81Å; F131-W133 PolarHBondContact O-N 3.38Å; W133-F136 PolarHBondContact O-N 3.01Å; W133-T137 WeakPolarHBondContact O-CG2 3.38Å; W133-T137 PolarHBondContact O-N 3.18Å; W133-T137 VanDerWaalsContact O-N 3.09Å; W133-T137 PolarHBondContact O-OG1 3.24Å; W133-Y216 AromaticContact CZ2-CE2 3.93Å; W133-Y216 HydrophobicContact CZ2-CE2 3.93Å; W133-Y216 AromaticContact CZ2-CZ 3.93Å; W133-Y216 VanDerWaalsContact CZ2-OH 3.3Å; W133-Y216 WeakPolarHBondContact CZ2-OH 3.06Å; W133-Y216 AromaticContact NE1-CZ 3.56Å; W133-Y216 PolarHBondContact NE1-OH 3.49Å; W133-G257 VanDerWaalsContact CD1-O 3.22Å; W133-F260 HydrophobicContact CB-CB 3.81Å; W133-M261 HydrophobicContact CD2-CB 3.78Å; W133-M261 HydrophobicContact CD2-CG 3.98Å; W133-M261 VanDerWaalsContact CE2-CG 3.48Å; W133-M261 HydrophobicContact CE3-CB 4.44Å; W133-M261 HydrophobicContact CE3-CG 4.36Å; W133-M261 HydrophobicContact CG-CB 3.94Å; W133-M261 HydrophobicContact CH2-CG 3.93Å; W133-M261 HydrophobicContact CZ2-CB 4.14Å; W133-M261 HydrophobicContact CZ2-CG 3.48Å; W133-M261 VanDerWaalsContact CZ2-CG 3.48Å; W133-M261 HydrophobicContact CZ2-SD 3.87Å; W133-M261 HydrophobicContact CZ3-CG 4.34Å; W133-Y264 HydrophobicContact CE3-CD1 4.46Å; W133-Y264 HydrophobicContact CZ3-CD1 4.03Å; W133-Y264 HydrophobicContact CZ3-CE1 4.4Å; W133-Y265 AromaticContact CH2-CE2 3.66Å; W133-Y265 HydrophobicContact CH2-CE2 3.66Å; W133-Y265 HydrophobicContact CZ2-CE2 4.45Å; W133-Y265 AromaticContact CZ3-CE2 3.93Å; W133-Y265 HydrophobicContact CZ3-CE2 3.93Å
134	H	87.9	Confident	86.7	Confident	0 Å²	0	33 Å²	33	0%	0	16%	0.158	C	C	.	.	H	α-helix	trans	-61.4	-48.1	-179.8	-75.9	-59	0	0	0	112.3	Q109 Q130 F131 C132 F136 T137 I138 S199	Q109-H134 PolarHBondContact NE2-NE2 3.01Å; Q109-H134 PolarHBondContact OE1-NE2 3.48Å; Q130-H134 PolarHBondContact O-CD2 3.12Å; Q130-H134 PolarHBondContact O-N 3.18Å; F131-H134 PolarHBondContact O-N 3.45Å; C132-H134 PolarHBondContact O-N 2.92Å; H134-F136 PolarHBondContact O-N 3.43Å; H134-T137 PolarHBondContact O-N 2.86Å; H134-T137 PolarHBondContact O-OG1 3.48Å; H134-T137 VanDerWaalsContact O-OG1 3.09Å; H134-I138 HydrophobicContact CB-CD1 4.14Å; H134-I138 WeakPolarHBondContact O-CB 3.4Å; H134-I138 VanDerWaalsContact O-CD1 3.3Å; H134-I138 WeakPolarHBondContact O-CD1 3.12Å; H134-I138 WeakPolarHBondContact O-CG1 3.39Å; H134-I138 PolarHBondContact O-N 3.35Å; H134-S199 PolarHBondContact ND1-OG 3.41Å
135	F	88.9	Confident	87.4	Confident	51 Å²	51	23.8 Å²	23.8	22%	0.224	12%	0.122	C	C	.	.	H	α-helix	trans	-53.5	-50.5	179.4	177.4	-99.3	0	0	0	112.1	L98 V99 A102 F131 C132 A139	L98-F135 HydrophobicContact CD2-CD2 3.61Å; L98-F135 HydrophobicContact CD2-CE2 3.69Å; L98-F135 HydrophobicContact CD2-CG 4.47Å; V99-F135 HydrophobicContact CG2-CD2 4.11Å; V99-F135 HydrophobicContact CG2-CE2 3.59Å; V99-F135 HydrophobicContact CG2-CZ 4.43Å; A102-F135 HydrophobicContact CB-CB 3.99Å; A102-F135 HydrophobicContact CB-CD2 4.29Å; F131-F135 HydrophobicContact CZ-CB 4.48Å; F131-F135 HydrophobicContact CZ-CD2 4.48Å; F131-F135 VanDerWaalsContact O-CB 3.26Å; F131-F135 WeakPolarHBondContact O-CB 3.49Å; F131-F135 PolarHBondContact O-N 2.96Å; C132-F135 PolarHBondContact O-N 2.91Å; F135-A139 WeakPolarHBondContact O-CB 3.39Å; F135-A139 PolarHBondContact O-N 3Å
136	F	91	Very high	87.9	Confident	60 Å²	60	18.4 Å²	18.4	26%	0.263	9%	0.094	S	C	.	.	H	α-helix	trans	-68.8	-39.9	-178.7	-78	-60.9	0	0	0	113.2	C132 W133 H134 A140 S253 T256 F260	C132-F136 HydrophobicContact CB-CD2 4.35Å; C132-F136 HydrophobicContact CB-CE2 4.37Å; C132-F136 WeakPolarHBondContact O-CB 3.34Å; C132-F136 WeakPolarHBondContact O-CD2 3.42Å; C132-F136 PolarHBondContact O-N 3.45Å; W133-F136 PolarHBondContact O-N 3.01Å; H134-F136 PolarHBondContact O-N 3.43Å; F136-A140 PolarHBondContact O-N 3.04Å; F136-A140 VanDerWaalsContact O-N 3.12Å; F136-S253 WeakPolarHBondContact CB-O 3.22Å; F136-T256 HydrophobicContact CD1-CG2 4.28Å; F136-T256 HydrophobicContact CD2-CG2 3.73Å; F136-T256 HydrophobicContact CE1-CG2 4.33Å; F136-T256 HydrophobicContact CE2-CG2 3.81Å; F136-T256 HydrophobicContact CG-CG2 4.01Å; F136-T256 HydrophobicContact CZ-CG2 4.11Å; F136-F260 AromaticContact CD2-CD2 3.76Å; F136-F260 HydrophobicContact CD2-CD2 3.76Å; F136-F260 AromaticContact CD2-CE2 3.75Å; F136-F260 HydrophobicContact CD2-CE2 3.75Å; F136-F260 HydrophobicContact CE2-CD2 4.05Å; F136-F260 AromaticContact CE2-CE2 3.54Å; F136-F260 HydrophobicContact CE2-CE2 3.54Å; F136-F260 HydrophobicContact CE2-CZ 4.45Å
137	T	90.8	Very high	88.4	Confident	8 Å²	8	18.6 Å²	18.6	5%	0.049	10%	0.095	C	C	.	.	H	α-helix	trans	-68.1	-39	178	52.1	0	0	0	0	112.7	W133 H134 R141 Y216	W133-T137 WeakPolarHBondContact O-CG2 3.38Å; W133-T137 PolarHBondContact O-N 3.18Å; W133-T137 VanDerWaalsContact O-N 3.09Å; W133-T137 PolarHBondContact O-OG1 3.24Å; H134-T137 PolarHBondContact O-N 2.86Å; H134-T137 PolarHBondContact O-OG1 3.48Å; H134-T137 VanDerWaalsContact O-OG1 3.09Å; T137-R141 PolarHBondContact O-N 2.91Å; T137-Y216 HydrophobicContact CG2-CE1 3.84Å
138	I	90.3	Very high	88.9	Confident	2 Å²	2	18.2 Å²	18.2	1%	0.01	9%	0.092	C	C	.	.	H	α-helix	trans	-71.3	-41.5	178.2	-65.6	162.8	0	0	0	110.3	L98 L101 L105 H134 A140 R141 V142	L98-I138 HydrophobicContact CD2-CB 4.35Å; L98-I138 HydrophobicContact CD2-CG2 4.04Å; L98-I138 HydrophobicContact CG-CG2 4.23Å; L101-I138 HydrophobicContact CD2-CD1 3.88Å; L101-I138 HydrophobicContact CD2-CG2 4.26Å; L105-I138 HydrophobicContact CD1-CD1 3.36Å; H134-I138 HydrophobicContact CB-CD1 4.14Å; H134-I138 WeakPolarHBondContact O-CB 3.4Å; H134-I138 VanDerWaalsContact O-CD1 3.3Å; H134-I138 WeakPolarHBondContact O-CD1 3.12Å; H134-I138 WeakPolarHBondContact O-CG1 3.39Å; H134-I138 PolarHBondContact O-N 3.35Å; I138-A140 PolarHBondContact O-N 3.09Å; I138-R141 PolarHBondContact O-N 3.3Å; I138-V142 HydrophobicContact CG2-CG2 3.98Å; I138-V142 WeakPolarHBondContact O-CB 3.43Å; I138-V142 VanDerWaalsContact O-CG2 3.3Å; I138-V142 WeakPolarHBondContact O-CG2 3.17Å; I138-V142 PolarHBondContact O-N 3.45Å
139	A	90.8	Very high	89.1	Confident	11 Å²	11	13.7 Å²	13.7	9%	0.091	7%	0.069	C	C	.	.	H	α-helix	trans	-57.2	-49.6	175.7	0	0	0	0	0	111.7	L98 F135 R141 V142 I143	L98-A139 HydrophobicContact CD1-CB 4.11Å; L98-A139 HydrophobicContact CD2-CB 4.2Å; F135-A139 WeakPolarHBondContact O-CB 3.39Å; F135-A139 PolarHBondContact O-N 3Å; A139-R141 VanDerWaalsContact C-N 3.31Å; A139-R141 PolarHBondContact O-N 3.35Å; A139-V142 PolarHBondContact O-N 3.2Å; A139-I143 WeakPolarHBondContact O-CB 3.35Å; A139-I143 WeakPolarHBondContact O-CD1 3.4Å; A139-I143 WeakPolarHBondContact O-CG1 3.33Å; A139-I143 PolarHBondContact O-N 3.02Å
140	A	92.6	Very high	89.1	Confident	0 Å²	0	14.7 Å²	14.7	0%	0	8%	0.077	C	C	.	.	H	α-helix	trans	-55.7	-45.9	176.5	0	0	0	0	0	112.1	F136 I138 T144 S253 F254	F136-A140 PolarHBondContact O-N 3.04Å; F136-A140 VanDerWaalsContact O-N 3.12Å; I138-A140 PolarHBondContact O-N 3.09Å; A140-T144 WeakPolarHBondContact O-CB 3.34Å; A140-T144 PolarHBondContact O-N 2.64Å; A140-T144 PolarHBondContact O-OG1 2.89Å; A140-S253 WeakPolarHBondContact CB-OG 3.47Å; A140-F254 HydrophobicContact CB-CB 3.79Å; A140-F254 HydrophobicContact CB-CD2 4.22Å
141	R	93.1	Very high	89.2	Confident	1 Å²	1	17 Å²	17	0%	0.004	9%	0.091	C	C	.	.	H	α-helix	trans	-65.9	-48.9	-178.8	-171.2	59.8	162.6	-173.7	1.6	112.5	T137 I138 A139 T144 F145 H163 I197 E222 N223	T137-R141 PolarHBondContact O-N 2.91Å; I138-R141 PolarHBondContact O-N 3.3Å; A139-R141 VanDerWaalsContact C-N 3.31Å; A139-R141 PolarHBondContact O-N 3.35Å; R141-T144 PolarHBondContact O-N 2.92Å; R141-F145 HydrophobicContact CG-CD2 4.46Å; R141-F145 HydrophobicContact CG-CE2 4.02Å; R141-F145 HydrophobicContact CG-CZ 4.08Å; R141-F145 WeakPolarHBondContact O-CG 3.3Å; R141-F145 PolarHBondContact O-N 2.95Å; R141-H163 PolarHBondContact NH2-CE1 3.43Å; R141-H163 PolarHBondContact NH2-NE2 2.85Å; R141-I197 PolarHBondContact NE-O 3.21Å; R141-I197 PolarHBondContact NH2-O 3.21Å; R141-E222 IonicContact CZ-OE2 2.82Å; R141-E222 VanDerWaalsContact CZ-OE2 3.24Å; R141-E222 IonicContact NH1-OE2 3.2Å; R141-E222 PolarHBondContact NH1-OE2 2.92Å; R141-E222 IonicContact NH2-OE2 3.95Å; R141-E222 PolarHBondContact NH2-OE2 2.9Å; R141-N223 WeakPolarHBondContact CD-OD1 3.49Å; R141-N223 PolarHBondContact NH1-OD1 3.33Å
142	V	90.8	Very high	89.2	Confident	2 Å²	2	17.2 Å²	17.2	1%	0.012	9%	0.092	C	C	.	.	H	α-helix	trans	-63.4	-42.8	179.5	167.8	0	0	0	0	111.6	L73 V74 L77 L98 I138 A139 F145 A146 F198	L73-V142 HydrophobicContact CD2-CG1 3.93Å; L73-V142 HydrophobicContact CD2-CG2 4.15Å; L73-V142 HydrophobicContact CG-CG1 3.86Å; V74-V142 HydrophobicContact CG2-CG1 4.23Å; V74-V142 HydrophobicContact CG2-CG2 4.48Å; L77-V142 HydrophobicContact CD1-CG1 4.11Å; L77-V142 HydrophobicContact CD2-CG1 4.02Å; L98-V142 HydrophobicContact CD1-CB 4.34Å; L98-V142 HydrophobicContact CD1-CG1 4.32Å; I138-V142 HydrophobicContact CG2-CG2 3.98Å; I138-V142 WeakPolarHBondContact O-CB 3.43Å; I138-V142 VanDerWaalsContact O-CG2 3.3Å; I138-V142 WeakPolarHBondContact O-CG2 3.17Å; I138-V142 PolarHBondContact O-N 3.45Å; A139-V142 PolarHBondContact O-N 3.2Å; V142-F145 PolarHBondContact O-N 3.49Å; V142-A146 WeakPolarHBondContact O-CB 3.36Å; V142-A146 PolarHBondContact O-N 3.27Å; V142-F198 HydrophobicContact CG2-CD1 4.22Å
143	I	90.1	Very high	88.8	Confident	44 Å²	44	22 Å²	22	23%	0.226	11%	0.111	C	C	.	.	H	α-helix	trans	-64.8	-42.6	176.4	-65.1	165.4	0	0	0	110.4	L77 A139 A146 L147 V249 I250	L77-I143 HydrophobicContact CD2-CG1 4.07Å; A139-I143 WeakPolarHBondContact O-CB 3.35Å; A139-I143 WeakPolarHBondContact O-CD1 3.4Å; A139-I143 WeakPolarHBondContact O-CG1 3.33Å; A139-I143 PolarHBondContact O-N 3.02Å; I143-A146 PolarHBondContact O-N 2.89Å; I143-L147 PolarHBondContact O-N 3.48Å; I143-V249 HydrophobicContact CD1-CG1 4.2Å; I143-I250 HydrophobicContact CB-CG1 4.32Å; I143-I250 HydrophobicContact CG2-CD1 4.04Å; I143-I250 HydrophobicContact CG2-CG1 3.79Å
144	T	92.6	Very high	88.5	Confident	0 Å²	0	27.9 Å²	27.9	0%	0	14%	0.143	C	C	.	.	H	α-helix	trans	-62.6	-45.2	178.1	-55.3	0	0	0	0	112.1	A140 R141 A146 L147 F148 N223 L226 I250	A140-T144 WeakPolarHBondContact O-CB 3.34Å; A140-T144 PolarHBondContact O-N 2.64Å; A140-T144 PolarHBondContact O-OG1 2.89Å; R141-T144 PolarHBondContact O-N 2.92Å; T144-A146 VanDerWaalsContact C-N 3.34Å; T144-A146 PolarHBondContact O-N 2.95Å; T144-L147 PolarHBondContact O-N 3.28Å; T144-F148 PolarHBondContact O-N 2.7Å; T144-N223 HydrophobicContact CG2-CB 4.41Å; T144-L226 HydrophobicContact CG2-CB 3.61Å; T144-L226 HydrophobicContact CG2-CD1 4.18Å; T144-I250 VanDerWaalsContact OG1-CG2 3.3Å; T144-I250 WeakPolarHBondContact OG1-CG2 3.23Å
145	F	91.3	Very high	88.5	Confident	0 Å²	0	34.8 Å²	34.8	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-59.8	-43.1	173.9	-73.3	-11	0	0	0	112.2	V74 R141 V142 F148 A149 F156 F159 I160 I197 F198 L226	V74-F145 HydrophobicContact CG1-CB 4.06Å; V74-F145 HydrophobicContact CG2-CB 4.27Å; V74-F145 HydrophobicContact CG2-CD2 4.26Å; R141-F145 HydrophobicContact CG-CD2 4.46Å; R141-F145 HydrophobicContact CG-CE2 4.02Å; R141-F145 HydrophobicContact CG-CZ 4.08Å; R141-F145 WeakPolarHBondContact O-CG 3.3Å; R141-F145 PolarHBondContact O-N 2.95Å; V142-F145 PolarHBondContact O-N 3.49Å; F145-F148 PolarHBondContact O-N 2.96Å; F145-A149 WeakPolarHBondContact O-CB 3.42Å; F145-A149 PolarHBondContact O-N 3.35Å; F145-F156 HydrophobicContact CB-CE2 3.8Å; F145-F156 HydrophobicContact CB-CZ 4.18Å; F145-F156 HydrophobicContact CD1-CE2 4.2Å; F145-F156 HydrophobicContact CD2-CE2 4.42Å; F145-F156 AromaticContact CG-CE2 3.91Å; F145-F156 HydrophobicContact CG-CE2 3.91Å; F145-F156 HydrophobicContact CG-CZ 4.42Å; F145-F159 AromaticContact CE1-CE1 3.71Å; F145-F159 HydrophobicContact CE1-CE1 3.71Å; F145-F159 HydrophobicContact CZ-CE1 4.24Å; F145-I160 HydrophobicContact CD2-CD1 4.3Å; F145-I160 HydrophobicContact CE1-CD1 4.45Å; F145-I160 HydrophobicContact CE2-CD1 3.87Å; F145-I160 HydrophobicContact CZ-CD1 3.92Å; F145-I197 HydrophobicContact CE2-CG2 3.93Å; F145-I197 HydrophobicContact CZ-CG2 4.03Å; F145-F198 HydrophobicContact CD2-CD1 4.18Å; F145-F198 HydrophobicContact CD2-CE1 4.18Å; F145-F198 HydrophobicContact CE2-CD1 4Å; F145-F198 HydrophobicContact CE2-CE1 4.18Å; F145-F198 HydrophobicContact CE2-CG 4.45Å; F145-L226 HydrophobicContact CD1-CD1 3.75Å; F145-L226 HydrophobicContact CE1-CD1 3.77Å
146	A	89.1	Confident	88.4	Confident	0 Å²	0	34.2 Å²	34.2	0%	0	17%	0.167	C	C	.	.	H	α-helix	trans	-67.6	-37.1	-179.6	0	0	0	0	0	112.9	L77 I81 V142 I143 T144 S150	L77-A146 HydrophobicContact CB-CB 3.46Å; L77-A146 VanDerWaalsContact CB-CB 3.46Å; L77-A146 HydrophobicContact CD2-CB 4.1Å; L77-A146 HydrophobicContact CG-CB 4.45Å; I81-A146 HydrophobicContact CD1-CB 3.56Å; V142-A146 WeakPolarHBondContact O-CB 3.36Å; V142-A146 PolarHBondContact O-N 3.27Å; I143-A146 PolarHBondContact O-N 2.89Å; T144-A146 VanDerWaalsContact C-N 3.34Å; T144-A146 PolarHBondContact O-N 2.95Å; A146-S150 PolarHBondContact O-N 2.95Å; A146-S150 VanDerWaalsContact O-N 3.14Å
147	L	87.3	Confident	88.2	Confident	4 Å²	4	33.2 Å²	33.2	2%	0.021	17%	0.174	C	C	.	.	H	α-helix	trans	-63.8	-51.7	170.7	-72.1	-174.7	0	0	0	111.1	I81 I143 T144 A149 S150 W230 A246 I250	I81-L147 HydrophobicContact CD1-CD2 4.11Å; I81-L147 HydrophobicContact CG2-CD2 4.48Å; I143-L147 PolarHBondContact O-N 3.48Å; T144-L147 PolarHBondContact O-N 3.28Å; L147-A149 VanDerWaalsContact C-N 3.34Å; L147-A149 PolarHBondContact O-N 3.22Å; L147-S150 WeakPolarHBondContact O-CB 3.14Å; L147-S150 PolarHBondContact O-N 3.32Å; L147-S150 PolarHBondContact O-OG 3.04Å; L147-W230 HydrophobicContact CB-CD2 4.18Å; L147-W230 HydrophobicContact CB-CG 3.98Å; L147-W230 HydrophobicContact CD1-CD2 4.17Å; L147-W230 HydrophobicContact CD1-CE3 4.19Å; L147-W230 HydrophobicContact CD1-CH2 4.46Å; L147-W230 HydrophobicContact CD1-CZ2 4.47Å; L147-W230 HydrophobicContact CD1-CZ3 4.34Å; L147-W230 HydrophobicContact CD2-CH2 4.42Å; L147-W230 HydrophobicContact CD2-CZ2 3.83Å; L147-W230 PolarHBondContact O-NE1 2.89Å; L147-A246 HydrophobicContact CD1-CB 4.27Å; L147-I250 HydrophobicContact CD1-CD1 3.53Å
148	F	89.1	Confident	88.1	Confident	12 Å²	12	37.5 Å²	37.5	5%	0.053	20%	0.195	C	C	.	.	H	α-helix	trans	-60.3	-43.7	-179.3	-177.9	-98.9	0	0	0	112.2	T144 F145 S150 V151 F152 F156 L226 L229	T144-F148 PolarHBondContact O-N 2.7Å; F145-F148 PolarHBondContact O-N 2.96Å; F148-S150 PolarHBondContact O-N 3.06Å; F148-V151 PolarHBondContact O-N 2.87Å; F148-F152 HydrophobicContact CD2-CD2 4.26Å; F148-F152 HydrophobicContact CE1-CB 4.12Å; F148-F152 HydrophobicContact CE2-CB 4.35Å; F148-F152 AromaticContact CE2-CD2 3.77Å; F148-F152 HydrophobicContact CE2-CD2 3.77Å; F148-F152 HydrophobicContact CE2-CG 4.44Å; F148-F152 HydrophobicContact CZ-CB 3.96Å; F148-F152 HydrophobicContact CZ-CD2 4.16Å; F148-F152 HydrophobicContact CZ-CG 4.4Å; F148-F152 PolarHBondContact O-N 3.26Å; F148-F156 HydrophobicContact CD1-CB 4.07Å; F148-F156 HydrophobicContact CD1-CD2 4.02Å; F148-F156 HydrophobicContact CE1-CB 4.13Å; F148-L226 HydrophobicContact CB-CB 4.35Å; F148-L226 HydrophobicContact CB-CD2 4.39Å; F148-L226 HydrophobicContact CD1-CD2 3.98Å; F148-L226 HydrophobicContact CD2-CB 4.38Å; F148-L226 HydrophobicContact CD2-CD2 3.73Å; F148-L226 HydrophobicContact CE1-CD2 4.14Å; F148-L226 HydrophobicContact CE2-CD2 3.93Å; F148-L226 HydrophobicContact CG-CB 4.48Å; F148-L226 HydrophobicContact CG-CD2 3.76Å; F148-L226 HydrophobicContact CZ-CD2 4.12Å; F148-L229 HydrophobicContact CD2-CB 4.29Å; F148-L229 HydrophobicContact CE2-CB 4.02Å; F148-L229 HydrophobicContact CE2-CD1 3.96Å
149	A	87.8	Confident	88.2	Confident	4 Å²	4	39.3 Å²	39.3	3%	0.033	20%	0.203	C	C	.	.	H	α-helix	trans	-63.8	-23.3	175.4	0	0	0	0	0	113.4	F145 L147 V151 Q153 F156	F145-A149 WeakPolarHBondContact O-CB 3.42Å; F145-A149 PolarHBondContact O-N 3.35Å; L147-A149 VanDerWaalsContact C-N 3.34Å; L147-A149 PolarHBondContact O-N 3.22Å; A149-V151 PolarHBondContact O-N 2.96Å; A149-Q153 VanDerWaalsContact O-CG 3.25Å; A149-Q153 WeakPolarHBondContact O-CG 3.32Å; A149-F156 HydrophobicContact CB-CB 4.23Å; A149-F156 HydrophobicContact CB-CD1 3.9Å; A149-F156 HydrophobicContact CB-CD2 4.22Å; A149-F156 HydrophobicContact CB-CE1 4.35Å; A149-F156 HydrophobicContact CB-CG 3.83Å
150	S	84.3	Confident	88.1	Confident	32 Å²	32	40.6 Å²	40.6	22%	0.224	21%	0.208	C	C	.	.	H	α-helix	trans	-70.3	-19.9	176.7	95.2	0	0	0	0	113.3	A146 L147 F148	A146-S150 PolarHBondContact O-N 2.95Å; A146-S150 VanDerWaalsContact O-N 3.14Å; L147-S150 WeakPolarHBondContact O-CB 3.14Å; L147-S150 PolarHBondContact O-N 3.32Å; L147-S150 PolarHBondContact O-OG 3.04Å; F148-S150 PolarHBondContact O-N 3.06Å
151	V	84.3	Confident	88.1	Confident	53 Å²	53	44.6 Å²	44.6	32%	0.321	23%	0.233	S	C	.	.	H	α-helix	trans	-108.3	-40.9	177.9	-178.6	0	0	0	0	111.1	F148 A149	F148-V151 PolarHBondContact O-N 2.87Å; A149-V151 PolarHBondContact O-N 2.96Å
152	F	83.6	Confident	88	Confident	46 Å²	46	49.3 Å²	49.3	20%	0.202	26%	0.257	C	S	.	.			trans	-124.3	60.7	-169.1	-67.1	-65.7	0	0	0	113.5	F148 L154 Y155 F156 Y233	F148-F152 HydrophobicContact CD2-CD2 4.26Å; F148-F152 HydrophobicContact CE1-CB 4.12Å; F148-F152 HydrophobicContact CE2-CB 4.35Å; F148-F152 AromaticContact CE2-CD2 3.77Å; F148-F152 HydrophobicContact CE2-CD2 3.77Å; F148-F152 HydrophobicContact CE2-CG 4.44Å; F148-F152 HydrophobicContact CZ-CB 3.96Å; F148-F152 HydrophobicContact CZ-CD2 4.16Å; F148-F152 HydrophobicContact CZ-CG 4.4Å; F148-F152 PolarHBondContact O-N 3.26Å; F152-L154 VanDerWaalsContact C-N 3.33Å; F152-L154 PolarHBondContact O-N 3.34Å; F152-Y155 HydrophobicContact CB-CD2 4.19Å; F152-Y155 AromaticContact CD1-CD2 3.82Å; F152-Y155 HydrophobicContact CD1-CD2 3.82Å; F152-Y155 HydrophobicContact CD1-CE2 4.25Å; F152-Y155 HydrophobicContact CG-CD2 4.36Å; F152-Y155 PolarHBondContact O-N 3.25Å; F152-F156 WeakPolarHBondContact O-CB 3.16Å; F152-F156 PolarHBondContact O-N 2.92Å; F152-Y233 AromaticContact CE2-CD2 3.93Å; F152-Y233 HydrophobicContact CE2-CD2 3.93Å; F152-Y233 AromaticContact CE2-CG 3.95Å; F152-Y233 HydrophobicContact CE2-CG 3.95Å; F152-Y233 HydrophobicContact CZ-CD1 4.06Å; F152-Y233 AromaticContact CZ-CD2 3.79Å; F152-Y233 HydrophobicContact CZ-CD2 3.79Å; F152-Y233 AromaticContact CZ-CG 3.52Å; F152-Y233 HydrophobicContact CZ-CG 3.52Å
153	Q	80.6	Confident	88	Confident	127 Å²	127	49.3 Å²	49.3	59%	0.593	26%	0.257	S	S	*	.	H	α-helix	trans	-50.7	-44.1	-176.5	-65.5	-179	-2.2	0	0	114.4	A149	A149-Q153 VanDerWaalsContact O-CG 3.25Å; A149-Q153 WeakPolarHBondContact O-CG 3.32Å
154	L	83.1	Confident	88.1	Confident	129 Å²	129	50.7 Å²	50.7	68%	0.675	26%	0.26	S	S	*	.	H	α-helix	trans	-75.2	-44.1	-178	-166.2	153.4	0	0	0	112.2	F152 F156 G157 I158	F152-L154 VanDerWaalsContact C-N 3.33Å; F152-L154 PolarHBondContact O-N 3.34Å; L154-F156 VanDerWaalsContact C-N 3.27Å; L154-F156 PolarHBondContact O-N 3.42Å; L154-G157 PolarHBondContact O-N 2.94Å; L154-I158 HydrophobicContact CD2-CD1 3.84Å; L154-I158 PolarHBondContact O-N 3.22Å
155	Y	87.6	Confident	88.1	Confident	145 Å²	145	53.6 Å²	53.6	57%	0.569	28%	0.279	S	S	*	.	H	α-helix	trans	-67.7	-27.4	177	-61.9	-81.3	0	0	0	112.6	F152 G157 I158 F159	F152-Y155 HydrophobicContact CB-CD2 4.19Å; F152-Y155 AromaticContact CD1-CD2 3.82Å; F152-Y155 HydrophobicContact CD1-CD2 3.82Å; F152-Y155 HydrophobicContact CD1-CE2 4.25Å; F152-Y155 HydrophobicContact CG-CD2 4.36Å; F152-Y155 PolarHBondContact O-N 3.25Å; Y155-G157 VanDerWaalsContact C-N 3.33Å; Y155-G157 PolarHBondContact O-N 3.28Å; Y155-I158 HydrophobicContact CD1-CD1 4.46Å; Y155-I158 PolarHBondContact O-N 2.92Å; Y155-F159 WeakPolarHBondContact O-CB 3.41Å; Y155-F159 PolarHBondContact O-N 3.48Å
156	F	86.9	Confident	88	Confident	39 Å²	39	57.8 Å²	57.8	17%	0.171	30%	0.301	C	S	.	.	H	α-helix	trans	-59.4	-42.9	172.5	176.2	-111.4	0	0	0	111.9	V74 F145 F148 A149 F152 L154 I158 F159 I160	V74-F156 HydrophobicContact CG1-CE1 4.16Å; V74-F156 HydrophobicContact CG1-CZ 3.8Å; F145-F156 HydrophobicContact CB-CE2 3.8Å; F145-F156 HydrophobicContact CB-CZ 4.18Å; F145-F156 HydrophobicContact CD1-CE2 4.2Å; F145-F156 HydrophobicContact CD2-CE2 4.42Å; F145-F156 AromaticContact CG-CE2 3.91Å; F145-F156 HydrophobicContact CG-CE2 3.91Å; F145-F156 HydrophobicContact CG-CZ 4.42Å; F148-F156 HydrophobicContact CD1-CB 4.07Å; F148-F156 HydrophobicContact CD1-CD2 4.02Å; F148-F156 HydrophobicContact CE1-CB 4.13Å; A149-F156 HydrophobicContact CB-CB 4.23Å; A149-F156 HydrophobicContact CB-CD1 3.9Å; A149-F156 HydrophobicContact CB-CD2 4.22Å; A149-F156 HydrophobicContact CB-CE1 4.35Å; A149-F156 HydrophobicContact CB-CG 3.83Å; F152-F156 WeakPolarHBondContact O-CB 3.16Å; F152-F156 PolarHBondContact O-N 2.92Å; L154-F156 VanDerWaalsContact C-N 3.27Å; L154-F156 PolarHBondContact O-N 3.42Å; F156-I158 PolarHBondContact O-N 3.08Å; F156-F159 PolarHBondContact O-N 3.39Å; F156-I160 HydrophobicContact CD2-CG1 4.09Å; F156-I160 HydrophobicContact CE1-CG1 4.07Å; F156-I160 HydrophobicContact CE2-CD1 3.71Å; F156-I160 HydrophobicContact CE2-CG1 3.6Å; F156-I160 HydrophobicContact CZ-CD1 3.78Å; F156-I160 HydrophobicContact CZ-CG1 3.57Å; F156-I160 WeakPolarHBondContact O-CG1 3.18Å; F156-I160 PolarHBondContact O-N 2.78Å
157	G	86	Confident	88	Confident	38 Å²	38	58.2 Å²	58.2	39%	0.392	30%	0.303	S	S	.	.	H	α-helix	trans	-60.6	-44.8	174.5	0	0	0	0	0	112.7	L154 Y155 I160 V161	L154-G157 PolarHBondContact O-N 2.94Å; Y155-G157 VanDerWaalsContact C-N 3.33Å; Y155-G157 PolarHBondContact O-N 3.28Å; G157-I160 PolarHBondContact O-N 3.36Å; G157-V161 WeakPolarHBondContact O-CG2 3.39Å; G157-V161 PolarHBondContact O-N 3.45Å; G157-V161 VanDerWaalsContact O-N 3.14Å
158	I	89.8	Confident	88	Confident	99 Å²	99	58.7 Å²	58.7	51%	0.508	31%	0.306	S	S	.	.	H	α-helix	trans	-62.6	-44.8	176.7	-59.3	172.6	0	0	0	110.7	L154 Y155 F156 V161 L162	L154-I158 HydrophobicContact CD2-CD1 3.84Å; L154-I158 PolarHBondContact O-N 3.22Å; Y155-I158 HydrophobicContact CD1-CD1 4.46Å; Y155-I158 PolarHBondContact O-N 2.92Å; F156-I158 PolarHBondContact O-N 3.08Å; I158-V161 PolarHBondContact O-N 3.39Å; I158-L162 VanDerWaalsContact O-CB 3.32Å; I158-L162 WeakPolarHBondContact O-CB 3.23Å; I158-L162 PolarHBondContact O-N 2.81Å
159	F	91.2	Very high	87.9	Confident	39 Å²	39	64.3 Å²	64.3	17%	0.171	33%	0.331	C	S	.	.	H	α-helix	trans	-59.8	-46.3	177.8	174.2	-90.6	0	0	0	111.9	F145 Y155 F156 V161 L162 H163 L226	F145-F159 AromaticContact CE1-CE1 3.71Å; F145-F159 HydrophobicContact CE1-CE1 3.71Å; F145-F159 HydrophobicContact CZ-CE1 4.24Å; Y155-F159 WeakPolarHBondContact O-CB 3.41Å; Y155-F159 PolarHBondContact O-N 3.48Å; F156-F159 PolarHBondContact O-N 3.39Å; F159-V161 PolarHBondContact O-N 2.74Å; F159-L162 PolarHBondContact O-N 3.06Å; F159-H163 HydrophobicContact CE1-CB 4.26Å; F159-H163 HydrophobicContact CZ-CB 4.3Å; F159-H163 WeakPolarHBondContact O-CB 3.3Å; F159-H163 PolarHBondContact O-N 3.34Å; F159-L226 HydrophobicContact CD2-CD2 4.22Å; F159-L226 HydrophobicContact CE1-CD1 3.9Å; F159-L226 HydrophobicContact CE2-CD1 4.5Å; F159-L226 HydrophobicContact CE2-CD2 4.13Å; F159-L226 HydrophobicContact CG-CD2 4.44Å; F159-L226 HydrophobicContact CZ-CD1 3.87Å; F159-L226 HydrophobicContact CZ-CD2 4.29Å; F159-L226 HydrophobicContact CZ-CG 4.37Å
160	I	90.1	Very high	87.8	Confident	38 Å²	38	68.9 Å²	68.9	20%	0.195	35%	0.347	C	S	.	.	H	α-helix	trans	-62.6	-43.6	179.6	-69.7	-68.1	0	0	0	111.4	F145 F156 G157 W164 I197	F145-I160 HydrophobicContact CD2-CD1 4.3Å; F145-I160 HydrophobicContact CE1-CD1 4.45Å; F145-I160 HydrophobicContact CE2-CD1 3.87Å; F145-I160 HydrophobicContact CZ-CD1 3.92Å; F156-I160 HydrophobicContact CD2-CG1 4.09Å; F156-I160 HydrophobicContact CE1-CG1 4.07Å; F156-I160 HydrophobicContact CE2-CD1 3.71Å; F156-I160 HydrophobicContact CE2-CG1 3.6Å; F156-I160 HydrophobicContact CZ-CD1 3.78Å; F156-I160 HydrophobicContact CZ-CG1 3.57Å; F156-I160 WeakPolarHBondContact O-CG1 3.18Å; F156-I160 PolarHBondContact O-N 2.78Å; G157-I160 PolarHBondContact O-N 3.36Å; I160-W164 VanDerWaalsContact O-CB 3.29Å; I160-W164 WeakPolarHBondContact O-CB 3.21Å; I160-W164 PolarHBondContact O-N 3.08Å; I160-I197 HydrophobicContact CD1-CG2 3.83Å; I160-I197 HydrophobicContact CG2-CD1 4.35Å
161	V	90.6	Very high	87.7	Confident	85 Å²	85	67.5 Å²	67.5	52%	0.515	34%	0.337	S	S	.	.	H	α-helix	trans	-65.5	-44.7	176.8	174.8	0	0	0	0	111.2	G157 I158 F159 W164 C165	G157-V161 WeakPolarHBondContact O-CG2 3.39Å; G157-V161 PolarHBondContact O-N 3.45Å; G157-V161 VanDerWaalsContact O-N 3.14Å; I158-V161 PolarHBondContact O-N 3.39Å; F159-V161 PolarHBondContact O-N 2.74Å; V161-W164 PolarHBondContact O-N 3.15Å; V161-C165 PolarHBondContact O-N 3.3Å; V161-C165 PolarHBondContact O-SG 3Å
162	L	92.4	Very high	87.5	Confident	100 Å²	100	66.5 Å²	66.5	52%	0.524	33%	0.331	S	S	.	.	H	α-helix	trans	-62.5	-46.8	178.3	179.8	63.4	0	0	0	111.7	I158 F159 C165 I166	I158-L162 VanDerWaalsContact O-CB 3.32Å; I158-L162 WeakPolarHBondContact O-CB 3.23Å; I158-L162 PolarHBondContact O-N 2.81Å; F159-L162 PolarHBondContact O-N 3.06Å; L162-C165 PolarHBondContact O-N 2.86Å; L162-I166 HydrophobicContact CD1-CD1 4.15Å; L162-I166 HydrophobicContact CG-CD1 3.93Å; L162-I166 VanDerWaalsContact O-CG1 3.3Å; L162-I166 WeakPolarHBondContact O-CG1 3.3Å; L162-I166 PolarHBondContact O-N 3.1Å
163	H	91.3	Very high	87.1	Confident	2 Å²	2	70 Å²	70	1%	0.009	35%	0.347	C	S	.	.	H	α-helix	trans	-63.9	-40.3	178.3	-179.6	83.5	0	0	0	111.6	R141 F159 I166 M167 E222	R141-H163 PolarHBondContact NH2-CE1 3.43Å; R141-H163 PolarHBondContact NH2-NE2 2.85Å; F159-H163 HydrophobicContact CE1-CB 4.26Å; F159-H163 HydrophobicContact CZ-CB 4.3Å; F159-H163 WeakPolarHBondContact O-CB 3.3Å; F159-H163 PolarHBondContact O-N 3.34Å; H163-I166 PolarHBondContact O-N 2.69Å; H163-M167 WeakPolarHBondContact CE1-CE 3.19Å; H163-M167 WeakPolarHBondContact O-CB 3.49Å; H163-M167 WeakPolarHBondContact O-CG 3.42Å; H163-M167 PolarHBondContact O-N 2.88Å; H163-E222 VanDerWaalsContact CE1-CD 3.49Å; H163-E222 IonicContact CE1-OE1 2.73Å; H163-E222 PolarHBondContact CE1-OE1 3.37Å; H163-E222 IonicContact CE1-OE2 3.22Å; H163-E222 PolarHBondContact CE1-OE2 2.97Å; H163-E222 IonicContact CG-OE1 3.42Å; H163-E222 VanDerWaalsContact ND1-CD 3.31Å; H163-E222 IonicContact ND1-OE1 3.32Å; H163-E222 PolarHBondContact ND1-OE1 3.5Å; H163-E222 IonicContact ND1-OE2 2.71Å; H163-E222 PolarHBondContact ND1-OE2 3.19Å
164	W	91.8	Very high	86.4	Confident	73 Å²	73	65.5 Å²	65.5	28%	0.277	33%	0.33	S	S	.	.	H	α-helix	trans	-59.8	-46.4	172.2	173.7	62.3	0	0	0	112.4	I160 V161 I166 M167 T168 M190 I197	I160-W164 VanDerWaalsContact O-CB 3.29Å; I160-W164 WeakPolarHBondContact O-CB 3.21Å; I160-W164 PolarHBondContact O-N 3.08Å; V161-W164 PolarHBondContact O-N 3.15Å; W164-I166 PolarHBondContact O-N 2.91Å; W164-M167 PolarHBondContact O-N 2.93Å; W164-T168 PolarHBondContact NE1-OG1 2.95Å; W164-T168 VanDerWaalsContact O-CB 3.31Å; W164-T168 WeakPolarHBondContact O-CB 3.42Å; W164-T168 PolarHBondContact O-N 3.31Å; W164-T168 PolarHBondContact O-OG1 3.49Å; W164-M190 HydrophobicContact CZ2-CB 4.17Å; W164-M190 HydrophobicContact CZ2-CG 4.17Å; W164-M190 PolarHBondContact NE1-O 3.39Å; W164-M190 VanDerWaalsContact NE1-O 3.1Å; W164-I197 HydrophobicContact CB-CD1 3.81Å; W164-I197 HydrophobicContact CB-CG1 4.3Å; W164-I197 HydrophobicContact CG-CD1 4.27Å
165	C	91.3	Very high	85.3	Confident	61 Å²	61	60.2 Å²	60.2	41%	0.412	30%	0.302	S	S	.	.	H	α-helix	trans	-60	-44.8	176	-70.8	0	0	0	0	111.6	V161 L162 F169	V161-C165 PolarHBondContact O-N 3.3Å; V161-C165 PolarHBondContact O-SG 3Å; L162-C165 PolarHBondContact O-N 2.86Å; C165-F169 WeakPolarHBondContact O-CB 3.2Å; C165-F169 PolarHBondContact O-N 2.86Å
166	I	90.9	Very high	83.4	Confident	88 Å²	88	57.2 Å²	57.2	45%	0.451	30%	0.299	S	S	.	.	H	α-helix	trans	-62.8	-47.1	177.6	-68.6	165.6	0	0	0	111	L162 H163 W164 F169 W170	L162-I166 HydrophobicContact CD1-CD1 4.15Å; L162-I166 HydrophobicContact CG-CD1 3.93Å; L162-I166 VanDerWaalsContact O-CG1 3.3Å; L162-I166 WeakPolarHBondContact O-CG1 3.3Å; L162-I166 PolarHBondContact O-N 3.1Å; H163-I166 PolarHBondContact O-N 2.69Å; W164-I166 PolarHBondContact O-N 2.91Å; I166-F169 PolarHBondContact O-N 3.03Å; I166-W170 VanDerWaalsContact O-CB 3.26Å; I166-W170 WeakPolarHBondContact O-CB 3.37Å; I166-W170 PolarHBondContact O-N 3.18Å
167	M	88	Confident	81.4	Confident	8 Å²	8	62.3 Å²	62.3	4%	0.039	33%	0.328	C	S	.	.	H	α-helix	trans	-68.2	-41.4	-179	-72.9	-62.4	171.7	0	0	112.3	H163 W164 W170 I171 Y196 Y215 V218 I219	H163-M167 WeakPolarHBondContact CE1-CE 3.19Å; H163-M167 WeakPolarHBondContact O-CB 3.49Å; H163-M167 WeakPolarHBondContact O-CG 3.42Å; H163-M167 PolarHBondContact O-N 2.88Å; W164-M167 PolarHBondContact O-N 2.93Å; M167-W170 WeakPolarHBondContact O-CB 3.37Å; M167-W170 PolarHBondContact O-N 3.1Å; M167-I171 WeakPolarHBondContact O-CD1 3.47Å; M167-I171 VanDerWaalsContact O-CG1 3.25Å; M167-I171 WeakPolarHBondContact O-CG1 3.34Å; M167-I171 PolarHBondContact O-N 3.27Å; M167-Y196 HydrophobicContact SD-CD1 4.27Å; M167-Y215 HydrophobicContact CE-CD2 4.18Å; M167-Y215 HydrophobicContact CE-CE2 4.14Å; M167-Y215 HydrophobicContact SD-CD2 4.23Å; M167-Y215 HydrophobicContact SD-CE2 4.21Å; M167-V218 HydrophobicContact CE-CG1 3.8Å; M167-I219 HydrophobicContact CE-CD1 4.31Å
168	T	87.5	Confident	79.5	Confident	14 Å²	14	62.9 Å²	62.9	9%	0.086	32%	0.32	C	S	.	.	H	α-helix	trans	-62.9	-46.6	174.5	-57.9	0	0	0	0	111	W164 W170 I171 V172 M190	W164-T168 PolarHBondContact NE1-OG1 2.95Å; W164-T168 VanDerWaalsContact O-CB 3.31Å; W164-T168 WeakPolarHBondContact O-CB 3.42Å; W164-T168 PolarHBondContact O-N 3.31Å; W164-T168 PolarHBondContact O-OG1 3.49Å; T168-W170 VanDerWaalsContact C-N 3.31Å; T168-W170 PolarHBondContact O-N 2.81Å; T168-I171 PolarHBondContact O-N 3.38Å; T168-V172 HydrophobicContact CG2-CG2 4.47Å; T168-V172 WeakPolarHBondContact O-CG2 3.5Å; T168-V172 PolarHBondContact O-N 3.41Å; T168-M190 HydrophobicContact CG2-CB 4.42Å; T168-M190 HydrophobicContact CG2-CG 3.88Å
169	F	87.1	Confident	77.3	Confident	131 Å²	131	59.7 Å²	59.7	58%	0.575	31%	0.305	S	S	*	.	H	α-helix	trans	-61	-40.6	176	-176.3	-90.7	0	0	0	111.8	C165 I166 H173	C165-F169 WeakPolarHBondContact O-CB 3.2Å; C165-F169 PolarHBondContact O-N 2.86Å; I166-F169 PolarHBondContact O-N 3.03Å; F169-H173 AromaticContact CD1-CD2 3.8Å; F169-H173 AromaticContact CD2-CD2 3.68Å; F169-H173 AromaticContact CD2-NE2 3.91Å; F169-H173 AromaticContact CE1-CD2 3.48Å; F169-H173 VanDerWaalsContact CE1-CD2 3.48Å; F169-H173 WeakPolarHBondContact CE1-CD2 3.38Å; F169-H173 AromaticContact CE1-NE2 3.92Å; F169-H173 AromaticContact CE2-CD2 3.36Å; F169-H173 WeakPolarHBondContact CE2-CD2 3.42Å; F169-H173 AromaticContact CE2-NE2 3.18Å; F169-H173 WeakPolarHBondContact CE2-NE2 3.33Å; F169-H173 AromaticContact CG-CD2 3.89Å; F169-H173 AromaticContact CZ-CD2 3.25Å; F169-H173 WeakPolarHBondContact CZ-CD2 3.04Å; F169-H173 AromaticContact CZ-CE1 3.98Å; F169-H173 AromaticContact CZ-NE2 3.19Å; F169-H173 WeakPolarHBondContact CZ-NE2 3.21Å; F169-H173 WeakPolarHBondContact O-CB 3.48Å; F169-H173 PolarHBondContact O-CD2 3.09Å; F169-H173 PolarHBondContact O-N 3.4Å
170	W	86.4	Confident	75.4	Confident	100 Å²	100	66.5 Å²	66.5	38%	0.379	34%	0.342	S	S	.	.	H	α-helix	trans	-61.5	-43.9	175.2	-179.7	-82.6	0	0	0	112.4	I166 M167 T168 C174 I214	I166-W170 VanDerWaalsContact O-CB 3.26Å; I166-W170 WeakPolarHBondContact O-CB 3.37Å; I166-W170 PolarHBondContact O-N 3.18Å; M167-W170 WeakPolarHBondContact O-CB 3.37Å; M167-W170 PolarHBondContact O-N 3.1Å; T168-W170 VanDerWaalsContact C-N 3.31Å; T168-W170 PolarHBondContact O-N 2.81Å; W170-C174 WeakPolarHBondContact O-CB 3.01Å; W170-C174 PolarHBondContact O-N 3.31Å; W170-C174 PolarHBondContact O-SG 3.46Å; W170-I214 HydrophobicContact CH2-CD1 4.1Å; W170-I214 HydrophobicContact CH2-CG2 3.72Å; W170-I214 HydrophobicContact CZ2-CB 4.4Å; W170-I214 HydrophobicContact CZ2-CD1 4.13Å; W170-I214 HydrophobicContact CZ2-CG2 3.8Å
171	I	81.5	Confident	73.9	Confident	2 Å²	2	67.3 Å²	67.3	1%	0.01	35%	0.351	C	S	.	.	H	α-helix	trans	-60.8	-58.3	175.8	-67.8	155.1	0	0	0	109.3	M167 T168 H173 C174 E175 D189 V192 Y196	M167-I171 WeakPolarHBondContact O-CD1 3.47Å; M167-I171 VanDerWaalsContact O-CG1 3.25Å; M167-I171 WeakPolarHBondContact O-CG1 3.34Å; M167-I171 PolarHBondContact O-N 3.27Å; T168-I171 PolarHBondContact O-N 3.38Å; I171-H173 PolarHBondContact O-N 3.37Å; I171-C174 CarbonylContact O-C 3.56Å; I171-C174 WeakPolarHBondContact O-CA 3.36Å; I171-C174 PolarHBondContact O-N 2.72Å; I171-E175 VanDerWaalsContact O-CB 3.27Å; I171-E175 WeakPolarHBondContact O-CB 3.49Å; I171-E175 WeakPolarHBondContact O-CG 3.5Å; I171-E175 PolarHBondContact O-N 2.83Å; I171-D189 HydrophobicContact CG2-CB 4Å; I171-V192 HydrophobicContact CD1-CB 4.5Å; I171-V192 HydrophobicContact CD1-CG1 3.84Å; I171-Y196 HydrophobicContact CD1-CD1 4.13Å; I171-Y196 HydrophobicContact CD1-CD2 3.99Å; I171-Y196 HydrophobicContact CD1-CE1 4.36Å; I171-Y196 HydrophobicContact CD1-CE2 4.22Å; I171-Y196 HydrophobicContact CD1-CG 3.96Å; I171-Y196 HydrophobicContact CG1-CD1 4.35Å; I171-Y196 HydrophobicContact CG1-CE1 4.2Å
172	V	80.6	Confident	72.8	Confident	33 Å²	33	71 Å²	71	20%	0.2	36%	0.36	C	S	.	.	H	α-helix	trans	-52.1	-52.9	-179.1	173.1	0	0	0	0	110.7	T168 C174 E175 T176 D189	T168-V172 HydrophobicContact CG2-CG2 4.47Å; T168-V172 WeakPolarHBondContact O-CG2 3.5Å; T168-V172 PolarHBondContact O-N 3.41Å; V172-C174 VanDerWaalsContact C-N 3.28Å; V172-C174 PolarHBondContact O-N 3.17Å; V172-E175 PolarHBondContact O-N 2.89Å; V172-E175 VanDerWaalsContact O-N 3.08Å; V172-T176 HydrophobicContact CG1-CG2 3.8Å; V172-T176 VanDerWaalsContact O-CG2 3.23Å; V172-T176 WeakPolarHBondContact O-CG2 3.44Å; V172-T176 PolarHBondContact O-N 2.98Å; V172-T176 VanDerWaalsContact O-N 3.1Å; V172-T176 PolarHBondContact O-OG1 3.49Å; V172-D189 HydrophobicContact CG2-CB 3.84Å
173	H	74.3	Confident	71.9	Confident	118 Å²	118	76.6 Å²	76.6	55%	0.546	37%	0.374	S	S	.	.	H	α-helix	trans	-68.9	-19.9	179.8	-84.2	-84.8	0	0	0	115.1	F169 I171	F169-H173 AromaticContact CD1-CD2 3.8Å; F169-H173 AromaticContact CD2-CD2 3.68Å; F169-H173 AromaticContact CD2-NE2 3.91Å; F169-H173 AromaticContact CE1-CD2 3.48Å; F169-H173 VanDerWaalsContact CE1-CD2 3.48Å; F169-H173 WeakPolarHBondContact CE1-CD2 3.38Å; F169-H173 AromaticContact CE1-NE2 3.92Å; F169-H173 AromaticContact CE2-CD2 3.36Å; F169-H173 WeakPolarHBondContact CE2-CD2 3.42Å; F169-H173 AromaticContact CE2-NE2 3.18Å; F169-H173 WeakPolarHBondContact CE2-NE2 3.33Å; F169-H173 AromaticContact CG-CD2 3.89Å; F169-H173 AromaticContact CZ-CD2 3.25Å; F169-H173 WeakPolarHBondContact CZ-CD2 3.04Å; F169-H173 AromaticContact CZ-CE1 3.98Å; F169-H173 AromaticContact CZ-NE2 3.19Å; F169-H173 WeakPolarHBondContact CZ-NE2 3.21Å; F169-H173 WeakPolarHBondContact O-CB 3.48Å; F169-H173 PolarHBondContact O-CD2 3.09Å; F169-H173 PolarHBondContact O-N 3.4Å; I171-H173 PolarHBondContact O-N 3.37Å
174	C	66.6	Low	70.8	Confident	33 Å²	33	82.8 Å²	82.8	22%	0.223	40%	0.403	C	S	.	.	H	α-helix	trans	-86.2	-10.9	172.5	-79.7	0	0	0	0	113.4	W170 I171 V172 R211	W170-C174 WeakPolarHBondContact O-CB 3.01Å; W170-C174 PolarHBondContact O-N 3.31Å; W170-C174 PolarHBondContact O-SG 3.46Å; I171-C174 CarbonylContact O-C 3.56Å; I171-C174 WeakPolarHBondContact O-CA 3.36Å; I171-C174 PolarHBondContact O-N 2.72Å; V172-C174 VanDerWaalsContact C-N 3.28Å; V172-C174 PolarHBondContact O-N 3.17Å; C174-R211 VanDerWaalsContact O-CZ 3.23Å; C174-R211 PolarHBondContact O-NH1 3.05Å; C174-R211 PolarHBondContact O-NH2 3.18Å
175	E	58.9	Low	69.9	Low	19 Å²	19	80.4 Å²	80.4	9%	0.089	40%	0.395	C	S	.	.	H	α-helix	trans	-131.1	-3.1	-163.6	-66.6	-152	-168.5	0	0	116	I171 V172 D177 F178 K204	I171-E175 VanDerWaalsContact O-CB 3.27Å; I171-E175 WeakPolarHBondContact O-CB 3.49Å; I171-E175 WeakPolarHBondContact O-CG 3.5Å; I171-E175 PolarHBondContact O-N 2.83Å; V172-E175 PolarHBondContact O-N 2.89Å; V172-E175 VanDerWaalsContact O-N 3.08Å; E175-D177 VanDerWaalsContact C-N 3.28Å; E175-D177 PolarHBondContact O-N 3.38Å; E175-F178 WeakPolarHBondContact O-CD2 3.02Å; E175-K204 HydrophobicContact CG-CD 4.19Å; E175-K204 VanDerWaalsContact OE2-CD 3.24Å; E175-K204 WeakPolarHBondContact OE2-CD 3.38Å; E175-K204 WeakPolarHBondContact OE2-CE 3.14Å; E175-K204 IonicContact OE2-NZ 2.7Å; E175-K204 PolarHBondContact OE2-NZ 2.78Å
176	T	47.9	Very low	69.3	Low	82 Å²	82	80.5 Å²	80.5	50%	0.503	39%	0.391	S	S	.	.			trans	-62.7	13.4	-166.9	23.5	0	0	0	0	120.9	V172	V172-T176 HydrophobicContact CG1-CG2 3.8Å; V172-T176 VanDerWaalsContact O-CG2 3.23Å; V172-T176 WeakPolarHBondContact O-CG2 3.44Å; V172-T176 PolarHBondContact O-N 2.98Å; V172-T176 VanDerWaalsContact O-N 3.1Å; V172-T176 PolarHBondContact O-OG1 3.49Å
177	D	44.5	Very low	68.7	Low	145 Å²	145	80.6 Å²	80.6	78%	0.775	40%	0.396	S	S	*	.	S	Bend	trans	-118.4	36.6	-178.5	-82.4	-39.2	0	0	0	113.2	E175	E175-D177 VanDerWaalsContact C-N 3.28Å; E175-D177 PolarHBondContact O-N 3.38Å
178	F	46.5	Very low	68.1	Low	51 Å²	51	82 Å²	82	22%	0.224	40%	0.401	C	S	.	.			trans	-125.1	-48.4	-168.8	-81.5	-67.1	0	0	0	119.6	E175 K204 Q361	E175-F178 WeakPolarHBondContact O-CD2 3.02Å; F178-K204 HydrophobicContact CD2-CD 4.48Å; F178-K204 VanDerWaalsContact CD2-NZ 3.28Å; F178-Q361 HydrophobicContact CE1-CB 3.55Å; F178-Q361 HydrophobicContact CE1-CG 3.58Å; F178-Q361 WeakPolarHBondContact CE1-O 3.4Å; F178-Q361 VanDerWaalsContact CZ-C 3.48Å; F178-Q361 HydrophobicContact CZ-CB 4.03Å; F178-Q361 HydrophobicContact CZ-CG 3.71Å; F178-Q361 WeakPolarHBondContact CZ-O 3.39Å
179	C	44.7	Very low	67.8	Low	31 Å²	31	81.7 Å²	81.7	21%	0.209	40%	0.399	C	S	.	.			trans	-92.6	149.2	-168.4	-63.8	0	0	0	0	115.4	S181 E185 E366	C179-S181 VanDerWaalsContact C-N 3.29Å; C179-S181 PolarHBondContact O-N 2.91Å; C179-E185 HydrophobicContact CB-CB 3.8Å; C179-E185 HydrophobicContact CB-CG 4.03Å; C179-E185 WeakPolarHBondContact CB-OE2 3.22Å; C179-E185 PolarHBondContact N-OE1 3.48Å; C179-E185 VanDerWaalsContact SG-CD 3.51Å; C179-E366 PolarHBondContact SG-OE1 3.13Å
180	I	50.1	Low	67.6	Low	182 Å²	182	79.3 Å²	79.3	93%	0.933	39%	0.391	S	S	*	.	S	Bend	trans	-70.3	-23.1	173.2	-75.9	171	0	0	0	112.4
181	S	59.1	Low	67.4	Low	56 Å²	56	76.4 Å²	76.4	39%	0.392	38%	0.384	S	S	.	.	S	Bend	trans	-134	96.5	-175.6	37.7	0	0	0	0	112.3	C179 W183 E184	C179-S181 VanDerWaalsContact C-N 3.29Å; C179-S181 PolarHBondContact O-N 2.91Å; S181-W183 PolarHBondContact O-N 3.48Å; S181-E184 PolarHBondContact O-N 3.28Å; S181-E184 VanDerWaalsContact O-N 3.13Å
182	K	67.7	Low	67.4	Low	162 Å²	162	76.4 Å²	76.4	70%	0.704	38%	0.384	S	S	*	.	H	α-helix	trans	-50	-31	-173.5	-71	-179.1	172.3	177.4	0	116.4	I186	K182-I186 WeakPolarHBondContact O-CD1 3.19Å; K182-I186 VanDerWaalsContact O-CG1 3.23Å; K182-I186 WeakPolarHBondContact O-CG1 3.3Å; K182-I186 PolarHBondContact O-N 2.98Å
183	W	73.5	Confident	67.6	Low	217 Å²	217	74.9 Å²	74.9	82%	0.822	38%	0.375	S	S	*	.	H	α-helix	trans	-74.1	-33.3	-177.2	-62.8	112.4	0	0	0	113.7	S181 V187	S181-W183 PolarHBondContact O-N 3.48Å; W183-V187 WeakPolarHBondContact O-CG2 3.28Å; W183-V187 PolarHBondContact O-N 2.91Å
184	E	68.6	Low	68.1	Low	132 Å²	132	71.6 Å²	71.6	62%	0.617	36%	0.361	S	S	*	.	H	α-helix	trans	-75.2	-39.4	-179.6	-171.1	170.1	179.6	0	0	110.9	S181 V187 F188	S181-E184 PolarHBondContact O-N 3.28Å; S181-E184 VanDerWaalsContact O-N 3.13Å; E184-V187 PolarHBondContact O-N 3.32Å; E184-F188 WeakPolarHBondContact O-CB 3.46Å; E184-F188 PolarHBondContact O-N 3.41Å
185	E	72.1	Confident	68.9	Low	23 Å²	23	70.2 Å²	70.2	11%	0.107	35%	0.351	C	S	.	.	H	α-helix	trans	-57.3	-51.7	172.1	-169.7	172.7	-149.3	0	0	111.6	C179 V187 F188 D189	C179-E185 HydrophobicContact CB-CB 3.8Å; C179-E185 HydrophobicContact CB-CG 4.03Å; C179-E185 WeakPolarHBondContact CB-OE2 3.22Å; C179-E185 PolarHBondContact N-OE1 3.48Å; C179-E185 VanDerWaalsContact SG-CD 3.51Å; E185-V187 VanDerWaalsContact C-N 3.33Å; E185-V187 PolarHBondContact O-N 3.44Å; E185-F188 PolarHBondContact O-N 2.97Å; E185-F188 VanDerWaalsContact O-N 3.15Å; E185-D189 WeakPolarHBondContact O-CB 3.26Å; E185-D189 PolarHBondContact O-N 3.08Å
186	I	77.9	Confident	70.3	Confident	64 Å²	64	69.6 Å²	69.6	33%	0.328	35%	0.348	S	S	.	.	H	α-helix	trans	-59.3	-41.6	178.9	-68.8	165	0	0	0	112	K182 D189 M190	K182-I186 WeakPolarHBondContact O-CD1 3.19Å; K182-I186 VanDerWaalsContact O-CG1 3.23Å; K182-I186 WeakPolarHBondContact O-CG1 3.3Å; K182-I186 PolarHBondContact O-N 2.98Å; I186-D189 PolarHBondContact O-N 3.02Å; I186-M190 HydrophobicContact CG2-CE 3.88Å; I186-M190 WeakPolarHBondContact O-CG 3.13Å; I186-M190 PolarHBondContact O-N 3.02Å
187	V	80.1	Confident	72.2	Confident	90 Å²	90	66 Å²	66	55%	0.545	33%	0.326	S	S	.	.	H	α-helix	trans	-67.4	-40.3	178.3	171	0	0	0	0	111	W183 E184 E185 V191	W183-V187 WeakPolarHBondContact O-CG2 3.28Å; W183-V187 PolarHBondContact O-N 2.91Å; E184-V187 PolarHBondContact O-N 3.32Å; E185-V187 VanDerWaalsContact C-N 3.33Å; E185-V187 PolarHBondContact O-N 3.44Å; V187-V191 WeakPolarHBondContact O-CB 3.48Å; V187-V191 WeakPolarHBondContact O-CG2 2.98Å; V187-V191 PolarHBondContact O-N 2.96Å
188	F	74.9	Confident	74.1	Confident	37 Å²	37	60 Å²	60	16%	0.162	29%	0.293	C	S	.	.	H	α-helix	trans	-64.2	-43.6	175.2	179.5	-90.2	0	0	0	111.9	M59 E184 E185 V191 V192 V203 W365	M59-F188 HydrophobicContact CE-CE2 4.33Å; M59-F188 HydrophobicContact SD-CE2 4.21Å; E184-F188 WeakPolarHBondContact O-CB 3.46Å; E184-F188 PolarHBondContact O-N 3.41Å; E185-F188 PolarHBondContact O-N 2.97Å; E185-F188 VanDerWaalsContact O-N 3.15Å; F188-V191 WeakPolarHBondContact O-CB 3.49Å; F188-V191 PolarHBondContact O-N 3.4Å; F188-V192 HydrophobicContact CD1-CG2 3.98Å; F188-V192 HydrophobicContact CE1-CG2 3.49Å; F188-V192 VanDerWaalsContact CE1-CG2 3.49Å; F188-V192 HydrophobicContact CE2-CG2 4.3Å; F188-V192 HydrophobicContact CZ-CG2 3.67Å; F188-V192 WeakPolarHBondContact O-CG2 3.44Å; F188-V192 PolarHBondContact O-N 3.41Å; F188-V203 HydrophobicContact CE1-CB 4.48Å; F188-V203 HydrophobicContact CE1-CG1 3.65Å; F188-V203 HydrophobicContact CE1-CG2 4Å; F188-V203 HydrophobicContact CZ-CG1 3.86Å; F188-V203 HydrophobicContact CZ-CG2 4.18Å; F188-W365 AromaticContact CE1-NE1 3.81Å; F188-W365 AromaticContact CZ-CD1 3.81Å; F188-W365 AromaticContact CZ-NE1 3.74Å
189	D	79.9	Confident	75.9	Confident	8 Å²	8	57.7 Å²	57.7	4%	0.043	28%	0.283	C	S	.	.	H	α-helix	trans	-66.9	-38	179	-74.7	-8	0	0	0	112.6	I171 V172 E185 I186 V191 V192 G193	I171-D189 HydrophobicContact CG2-CB 4Å; V172-D189 HydrophobicContact CG2-CB 3.84Å; E185-D189 WeakPolarHBondContact O-CB 3.26Å; E185-D189 PolarHBondContact O-N 3.08Å; I186-D189 PolarHBondContact O-N 3.02Å; D189-V191 VanDerWaalsContact C-N 3.3Å; D189-V191 PolarHBondContact O-N 3.21Å; D189-V192 PolarHBondContact O-N 2.95Å; D189-G193 PolarHBondContact O-N 3.05Å
190	M	83.8	Confident	77.6	Confident	81 Å²	81	57 Å²	57	40%	0.399	28%	0.276	S	S	.	.	H	α-helix	trans	-58.8	-43.5	170.8	-79.2	-177.5	-177.7	0	0	111.9	W164 T168 I186 G193 I194	W164-M190 HydrophobicContact CZ2-CB 4.17Å; W164-M190 HydrophobicContact CZ2-CG 4.17Å; W164-M190 PolarHBondContact NE1-O 3.39Å; W164-M190 VanDerWaalsContact NE1-O 3.1Å; T168-M190 HydrophobicContact CG2-CB 4.42Å; T168-M190 HydrophobicContact CG2-CG 3.88Å; I186-M190 HydrophobicContact CG2-CE 3.88Å; I186-M190 WeakPolarHBondContact O-CG 3.13Å; I186-M190 PolarHBondContact O-N 3.02Å; M190-G193 PolarHBondContact O-N 2.8Å; M190-I194 PolarHBondContact O-N 2.86Å
191	V	81.6	Confident	78.6	Confident	39 Å²	39	48.6 Å²	48.6	24%	0.236	23%	0.233	C	C	.	.	H	α-helix	trans	-67.6	-44.6	-179.2	160.5	0	0	0	0	111.3	L63 V187 F188 D189 G193 I194	L63-V191 HydrophobicContact CD1-CG1 3.4Å; L63-V191 VanDerWaalsContact CD1-CG1 3.4Å; L63-V191 HydrophobicContact CD2-CG1 3.36Å; L63-V191 HydrophobicContact CG-CG1 4Å; V187-V191 WeakPolarHBondContact O-CB 3.48Å; V187-V191 WeakPolarHBondContact O-CG2 2.98Å; V187-V191 PolarHBondContact O-N 2.96Å; F188-V191 WeakPolarHBondContact O-CB 3.49Å; F188-V191 PolarHBondContact O-N 3.4Å; D189-V191 VanDerWaalsContact C-N 3.3Å; D189-V191 PolarHBondContact O-N 3.21Å; V191-G193 VanDerWaalsContact C-N 3.33Å; V191-I194 PolarHBondContact O-N 3.2Å
192	V	81.1	Confident	78.9	Confident	2 Å²	2	48 Å²	48	1%	0.012	23%	0.225	C	C	.	.	H	α-helix	trans	-64	-38.7	172	168.2	0	0	0	0	111.4	I171 F188 D189 I194 I195 Y196 F201 V203	I171-V192 HydrophobicContact CD1-CB 4.5Å; I171-V192 HydrophobicContact CD1-CG1 3.84Å; F188-V192 HydrophobicContact CD1-CG2 3.98Å; F188-V192 HydrophobicContact CE1-CG2 3.49Å; F188-V192 VanDerWaalsContact CE1-CG2 3.49Å; F188-V192 HydrophobicContact CE2-CG2 4.3Å; F188-V192 HydrophobicContact CZ-CG2 3.67Å; F188-V192 WeakPolarHBondContact O-CG2 3.44Å; F188-V192 PolarHBondContact O-N 3.41Å; D189-V192 PolarHBondContact O-N 2.95Å; V192-I194 PolarHBondContact O-N 3.38Å; V192-I195 WeakPolarHBondContact O-CA 3.42Å; V192-I195 WeakPolarHBondContact O-CB 3.16Å; V192-I195 PolarHBondContact O-N 3.1Å; V192-Y196 HydrophobicContact CG1-CD2 3.68Å; V192-Y196 HydrophobicContact CG1-CE2 3.5Å; V192-Y196 VanDerWaalsContact CG1-CE2 3.5Å; V192-Y196 WeakPolarHBondContact O-CD2 3.33Å; V192-Y196 PolarHBondContact O-N 3.49Å; V192-F201 HydrophobicContact CG1-CD1 3.94Å; V192-F201 HydrophobicContact CG2-CD1 4.02Å; V192-F201 HydrophobicContact CG2-CE1 4Å; V192-V203 HydrophobicContact CG1-CG2 3.89Å; V192-V203 HydrophobicContact CG2-CG2 3.85Å
193	G	86.8	Confident	78.4	Confident	0 Å²	0	40.4 Å²	40.4	0%	0	19%	0.192	C	C	.	.	H	α-helix	trans	-55.9	-32.3	175.5	0	0	0	0	0	113.3	D189 M190 V191 Y196 I197	D189-G193 PolarHBondContact O-N 3.05Å; M190-G193 PolarHBondContact O-N 2.8Å; V191-G193 VanDerWaalsContact C-N 3.33Å; G193-Y196 PolarHBondContact O-N 2.86Å; G193-I197 WeakPolarHBondContact O-CG1 3.38Å
194	I	84.1	Confident	77.4	Confident	50 Å²	50	31.2 Å²	31.2	26%	0.256	16%	0.158	S	C	.	.	H	α-helix	trans	-68.5	-37.1	173.4	-56.9	167.2	0	0	0	111.1	F66 L67 M190 V191 V192 Y196 I197	F66-I194 WeakPolarHBondContact CE1-O 3.46Å; L67-I194 HydrophobicContact CD2-CB 4Å; L67-I194 HydrophobicContact CD2-CD1 3.65Å; L67-I194 HydrophobicContact CD2-CG1 4.41Å; L67-I194 HydrophobicContact CD2-CG2 3.55Å; M190-I194 PolarHBondContact O-N 2.86Å; V191-I194 PolarHBondContact O-N 3.2Å; V192-I194 PolarHBondContact O-N 3.38Å; I194-Y196 VanDerWaalsContact C-N 3.34Å; I194-I197 HydrophobicContact CG2-CD1 4.18Å; I194-I197 WeakPolarHBondContact O-CB 3.38Å; I194-I197 WeakPolarHBondContact O-CG1 3.33Å; I194-I197 PolarHBondContact O-N 3.23Å
195	I	84	Confident	76.5	Confident	4 Å²	4	27.4 Å²	27.4	2%	0.021	14%	0.14	C	C	.	.	H	α-helix	trans	-65.9	-40.4	176.4	-50.4	-179.6	0	0	0	110.7	L63 F66 V192 I197 F198 S199 F201	L63-I195 HydrophobicContact CD1-CD1 4.12Å; L63-I195 HydrophobicContact CD1-CG1 4.38Å; F66-I195 HydrophobicContact CD1-CB 4.48Å; F66-I195 HydrophobicContact CD1-CG1 4.21Å; F66-I195 HydrophobicContact CD1-CG2 4.49Å; F66-I195 HydrophobicContact CD2-CG2 3.97Å; F66-I195 VanDerWaalsContact CE1-CA 3.47Å; F66-I195 HydrophobicContact CE1-CB 4.29Å; F66-I195 HydrophobicContact CE1-CG1 4.49Å; F66-I195 HydrophobicContact CE1-CG2 4.28Å; F66-I195 HydrophobicContact CE2-CG2 3.7Å; F66-I195 HydrophobicContact CG-CG1 4.36Å; F66-I195 HydrophobicContact CG-CG2 4.33Å; F66-I195 HydrophobicContact CZ-CB 4.28Å; F66-I195 HydrophobicContact CZ-CG2 3.83Å; F66-I195 VanDerWaalsContact CZ-O 3.23Å; F66-I195 WeakPolarHBondContact CZ-O 3.37Å; V192-I195 WeakPolarHBondContact O-CA 3.42Å; V192-I195 WeakPolarHBondContact O-CB 3.16Å; V192-I195 PolarHBondContact O-N 3.1Å; I195-I197 PolarHBondContact O-N 2.85Å; I195-I197 VanDerWaalsContact O-N 3.1Å; I195-F198 PolarHBondContact O-N 3.21Å; I195-F198 VanDerWaalsContact O-N 3.12Å; I195-S199 CarbonylContact C-O 3.56Å; I195-S199 PolarHBondContact O-N 2.83Å; I195-S199 VanDerWaalsContact O-O 3.08Å; I195-F201 HydrophobicContact CB-CB 4.12Å; I195-F201 HydrophobicContact CB-CG 4.46Å; I195-F201 HydrophobicContact CD1-CD1 4.18Å; I195-F201 HydrophobicContact CD1-CD2 4.35Å; I195-F201 HydrophobicContact CD1-CE1 4.34Å; I195-F201 HydrophobicContact CD1-CG 4.16Å; I195-F201 HydrophobicContact CG2-CB 3.65Å; I195-F201 HydrophobicContact CG2-CD2 4.31Å; I195-F201 HydrophobicContact CG2-CG 4.06Å
196	Y	87.6	Confident	75.4	Confident	6 Å²	6	28.1 Å²	28.1	2%	0.024	15%	0.153	C	C	.	.	H	α-helix	trans	-59.7	-21.1	178.5	-89.6	-122.2	0	0	0	114.5	M167 I171 V192 G193 I194 F198 S199 W200 F201 Y215	M167-Y196 HydrophobicContact SD-CD1 4.27Å; I171-Y196 HydrophobicContact CD1-CD1 4.13Å; I171-Y196 HydrophobicContact CD1-CD2 3.99Å; I171-Y196 HydrophobicContact CD1-CE1 4.36Å; I171-Y196 HydrophobicContact CD1-CE2 4.22Å; I171-Y196 HydrophobicContact CD1-CG 3.96Å; I171-Y196 HydrophobicContact CG1-CD1 4.35Å; I171-Y196 HydrophobicContact CG1-CE1 4.2Å; V192-Y196 HydrophobicContact CG1-CD2 3.68Å; V192-Y196 HydrophobicContact CG1-CE2 3.5Å; V192-Y196 VanDerWaalsContact CG1-CE2 3.5Å; V192-Y196 WeakPolarHBondContact O-CD2 3.33Å; V192-Y196 PolarHBondContact O-N 3.49Å; G193-Y196 PolarHBondContact O-N 2.86Å; I194-Y196 VanDerWaalsContact C-N 3.34Å; Y196-F198 PolarHBondContact O-N 3.26Å; Y196-S199 WeakPolarHBondContact CA-O 3.29Å; Y196-W200 HydrophobicContact CD1-CE3 4.3Å; Y196-W200 HydrophobicContact CD1-CZ3 4.42Å; Y196-W200 HydrophobicContact CE1-CD2 4.48Å; Y196-W200 AromaticContact CE1-CE3 3.51Å; Y196-W200 HydrophobicContact CE1-CE3 3.51Å; Y196-W200 HydrophobicContact CE1-CH2 4.29Å; Y196-W200 AromaticContact CE1-CZ3 3.41Å; Y196-W200 HydrophobicContact CE1-CZ3 3.41Å; Y196-W200 VanDerWaalsContact CE1-CZ3 3.41Å; Y196-W200 AromaticContact CZ-CE3 3.85Å; Y196-W200 AromaticContact CZ-CZ3 3.89Å; Y196-F201 HydrophobicContact CD2-CB 4.08Å; Y196-F201 HydrophobicContact CE2-CB 3.81Å; Y196-F201 WeakPolarHBondContact CE2-O 3.38Å; Y196-F201 PolarHBondContact OH-O 2.91Å; Y196-Y215 AromaticContact CD1-CD2 4Å; Y196-Y215 HydrophobicContact CD1-CD2 4Å; Y196-Y215 AromaticContact CD1-CE2 3.76Å; Y196-Y215 HydrophobicContact CD1-CE2 3.76Å; Y196-Y215 HydrophobicContact CE1-CD2 4.31Å; Y196-Y215 HydrophobicContact CE1-CE2 4.41Å; Y196-Y215 HydrophobicContact CG-CE2 4.38Å; Y196-Y215 PolarHBondContact O-OH 3.29Å
197	I	86.9	Confident	73.8	Confident	6 Å²	6	31 Å²	31	3%	0.031	18%	0.178	C	C	.	.	T	Hydrogen-bonded Turn	trans	-59.8	-34.6	175.8	-54.2	175.7	0	0	0	111.8	R141 F145 I160 W164 G193 I194 I195	R141-I197 PolarHBondContact NE-O 3.21Å; R141-I197 PolarHBondContact NH2-O 3.21Å; F145-I197 HydrophobicContact CE2-CG2 3.93Å; F145-I197 HydrophobicContact CZ-CG2 4.03Å; I160-I197 HydrophobicContact CD1-CG2 3.83Å; I160-I197 HydrophobicContact CG2-CD1 4.35Å; W164-I197 HydrophobicContact CB-CD1 3.81Å; W164-I197 HydrophobicContact CB-CG1 4.3Å; W164-I197 HydrophobicContact CG-CD1 4.27Å; G193-I197 WeakPolarHBondContact O-CG1 3.38Å; I194-I197 HydrophobicContact CG2-CD1 4.18Å; I194-I197 WeakPolarHBondContact O-CB 3.38Å; I194-I197 WeakPolarHBondContact O-CG1 3.33Å; I194-I197 PolarHBondContact O-N 3.23Å; I195-I197 PolarHBondContact O-N 2.85Å; I195-I197 VanDerWaalsContact O-N 3.1Å
198	F	85	Confident	72.9	Confident	20 Å²	20	29.6 Å²	29.6	9%	0.088	17%	0.17	C	C	.	.	T	Hydrogen-bonded Turn	trans	-118.8	-27.3	-176	-39.6	-119.6	0	0	0	114.5	F66 A70 V74 V142 F145 I195 Y196	F66-F198 HydrophobicContact CE1-CB 4.45Å; F66-F198 AromaticContact CE1-CD2 3.3Å; F66-F198 HydrophobicContact CE1-CD2 3.3Å; F66-F198 AromaticContact CE1-CE2 3.74Å; F66-F198 HydrophobicContact CE1-CE2 3.74Å; F66-F198 HydrophobicContact CE1-CG 4.12Å; F66-F198 HydrophobicContact CE2-CB 4.3Å; F66-F198 HydrophobicContact CZ-CB 3.61Å; F66-F198 AromaticContact CZ-CD2 3.35Å; F66-F198 HydrophobicContact CZ-CD2 3.35Å; F66-F198 HydrophobicContact CZ-CE2 4.23Å; F66-F198 AromaticContact CZ-CG 3.76Å; F66-F198 HydrophobicContact CZ-CG 3.76Å; A70-F198 HydrophobicContact CB-CD1 4.12Å; A70-F198 HydrophobicContact CB-CD2 4.21Å; A70-F198 HydrophobicContact CB-CE1 3.79Å; A70-F198 HydrophobicContact CB-CE2 3.9Å; A70-F198 HydrophobicContact CB-CG 4.33Å; A70-F198 HydrophobicContact CB-CZ 3.68Å; V74-F198 HydrophobicContact CG2-CD1 4.49Å; V74-F198 HydrophobicContact CG2-CE1 3.79Å; V142-F198 HydrophobicContact CG2-CD1 4.22Å; F145-F198 HydrophobicContact CD2-CD1 4.18Å; F145-F198 HydrophobicContact CD2-CE1 4.18Å; F145-F198 HydrophobicContact CE2-CD1 4Å; F145-F198 HydrophobicContact CE2-CE1 4.18Å; F145-F198 HydrophobicContact CE2-CG 4.45Å; I195-F198 PolarHBondContact O-N 3.21Å; I195-F198 VanDerWaalsContact O-N 3.12Å; Y196-F198 PolarHBondContact O-N 3.26Å
199	S	84.1	Confident	72.7	Confident	2 Å²	2	35 Å²	35	1%	0.014	19%	0.189	C	C	.	.	S	Bend	trans	-151.1	152.9	179.3	-161.6	0	0	0	0	114.2	H134 I195 Y196 F201 Y215	H134-S199 PolarHBondContact ND1-OG 3.41Å; I195-S199 CarbonylContact C-O 3.56Å; I195-S199 PolarHBondContact O-N 2.83Å; I195-S199 VanDerWaalsContact O-O 3.08Å; Y196-S199 WeakPolarHBondContact CA-O 3.29Å; S199-F201 PolarHBondContact O-N 2.89Å; S199-Y215 PolarHBondContact O-OH 3.48Å
200	W	81.3	Confident	72.5	Confident	16 Å²	16	43.2 Å²	43.2	6%	0.061	22%	0.221	C	C	.	.			trans	-69.2	109.7	172.8	179.4	-104.7	0	0	0	111.2	Y196 R211 L212 Y215 Y216	Y196-W200 HydrophobicContact CD1-CE3 4.3Å; Y196-W200 HydrophobicContact CD1-CZ3 4.42Å; Y196-W200 HydrophobicContact CE1-CD2 4.48Å; Y196-W200 AromaticContact CE1-CE3 3.51Å; Y196-W200 HydrophobicContact CE1-CE3 3.51Å; Y196-W200 HydrophobicContact CE1-CH2 4.29Å; Y196-W200 AromaticContact CE1-CZ3 3.41Å; Y196-W200 HydrophobicContact CE1-CZ3 3.41Å; Y196-W200 VanDerWaalsContact CE1-CZ3 3.41Å; Y196-W200 AromaticContact CZ-CE3 3.85Å; Y196-W200 AromaticContact CZ-CZ3 3.89Å; W200-R211 HydrophobicContact CH2-CB 4.45Å; W200-L212 HydrophobicContact CD2-CD1 3.97Å; W200-L212 HydrophobicContact CG-CD1 3.98Å; W200-L212 HydrophobicContact CZ2-CD1 4.09Å; W200-L212 VanDerWaalsContact NE1-CD1 3.29Å; W200-Y215 HydrophobicContact CB-CD1 3.91Å; W200-Y215 HydrophobicContact CB-CE1 3.58Å; W200-Y215 HydrophobicContact CD2-CD1 4.12Å; W200-Y215 HydrophobicContact CD2-CG 4.27Å; W200-Y215 AromaticContact CE3-CD1 3.51Å; W200-Y215 HydrophobicContact CE3-CD1 3.51Å; W200-Y215 AromaticContact CE3-CD2 3.62Å; W200-Y215 HydrophobicContact CE3-CD2 3.62Å; W200-Y215 HydrophobicContact CE3-CE1 4.08Å; W200-Y215 HydrophobicContact CE3-CE2 4.16Å; W200-Y215 AromaticContact CE3-CG 3.25Å; W200-Y215 HydrophobicContact CE3-CG 3.25Å; W200-Y215 HydrophobicContact CG-CD1 4.33Å; W200-Y215 HydrophobicContact CG-CE1 4.44Å; W200-Y215 VanDerWaalsContact CZ3-CB 3.46Å; W200-Y215 HydrophobicContact CZ3-CD1 4.32Å; W200-Y215 AromaticContact CZ3-CD2 3.94Å; W200-Y215 HydrophobicContact CZ3-CD2 3.94Å; W200-Y215 AromaticContact CZ3-CG 3.65Å; W200-Y215 HydrophobicContact CZ3-CG 3.65Å; W200-Y215 PolarHBondContact N-OH 3Å; W200-Y216 HydrophobicContact CB-CE2 4.21Å; W200-Y216 HydrophobicContact CG-CE2 4.46Å
201	F	70.8	Confident	72.3	Confident	5 Å²	5	43 Å²	43	2%	0.022	22%	0.216	C	C	.	.			trans	-105	88.5	178.6	-177	-107.1	0	0	0	111.5	L62 L105 Y108 V192 I195 Y196 S199 V203	L62-F201 HydrophobicContact CD2-CD2 3.93Å; L62-F201 HydrophobicContact CD2-CE2 3.33Å; L62-F201 HydrophobicContact CD2-CZ 4.2Å; L105-F201 HydrophobicContact CD2-CD2 4.09Å; Y108-F201 HydrophobicContact CD1-CD2 4.48Å; Y108-F201 AromaticContact CD1-CE2 3.45Å; Y108-F201 HydrophobicContact CD1-CE2 3.45Å; Y108-F201 VanDerWaalsContact CD1-CE2 3.45Å; Y108-F201 AromaticContact CD1-CZ 3.99Å; Y108-F201 HydrophobicContact CD1-CZ 3.99Å; Y108-F201 HydrophobicContact CE1-CD2 4.35Å; Y108-F201 HydrophobicContact CE1-CE1 4.47Å; Y108-F201 AromaticContact CE1-CE2 3.18Å; Y108-F201 HydrophobicContact CE1-CE2 3.18Å; Y108-F201 AromaticContact CE1-CZ 3.28Å; Y108-F201 HydrophobicContact CE1-CZ 3.28Å; Y108-F201 HydrophobicContact CG-CE2 4.49Å; Y108-F201 AromaticContact CZ-CZ 3.76Å; V192-F201 HydrophobicContact CG1-CD1 3.94Å; V192-F201 HydrophobicContact CG2-CD1 4.02Å; V192-F201 HydrophobicContact CG2-CE1 4Å; I195-F201 HydrophobicContact CB-CB 4.12Å; I195-F201 HydrophobicContact CB-CG 4.46Å; I195-F201 HydrophobicContact CD1-CD1 4.18Å; I195-F201 HydrophobicContact CD1-CD2 4.35Å; I195-F201 HydrophobicContact CD1-CE1 4.34Å; I195-F201 HydrophobicContact CD1-CG 4.16Å; I195-F201 HydrophobicContact CG2-CB 3.65Å; I195-F201 HydrophobicContact CG2-CD2 4.31Å; I195-F201 HydrophobicContact CG2-CG 4.06Å; Y196-F201 HydrophobicContact CD2-CB 4.08Å; Y196-F201 HydrophobicContact CE2-CB 3.81Å; Y196-F201 WeakPolarHBondContact CE2-O 3.38Å; Y196-F201 PolarHBondContact OH-O 2.91Å; S199-F201 PolarHBondContact O-N 2.89Å; F201-V203 HydrophobicContact CD1-CG2 3.65Å; F201-V203 HydrophobicContact CE1-CG2 3.7Å; F201-V203 PolarHBondContact O-N 3.48Å
202	N	65.5	Low	72.4	Confident	43 Å²	43	41.9 Å²	41.9	23%	0.23	21%	0.208	C	C	.	.			trans	-70.9	104.1	-176.7	-161.3	-1.5	0	0	0	113.1	K204	N202-K204 PolarHBondContact ND2-O 3.41Å; N202-K204 VanDerWaalsContact OD1-C 3.28Å; N202-K204 PolarHBondContact OD1-N 2.87Å; N202-K204 VanDerWaalsContact OD1-N 3.16Å; N202-K204 PolarHBondContact OD1-O 2.88Å
203	V	57.2	Low	72.5	Confident	3 Å²	3	45 Å²	45	2%	0.018	23%	0.23	C	C	.	.			trans	-79.9	-38.5	172.7	-175.3	0	0	0	0	111.8	F188 V192 F201 P363 A364	F188-V203 HydrophobicContact CE1-CB 4.48Å; F188-V203 HydrophobicContact CE1-CG1 3.65Å; F188-V203 HydrophobicContact CE1-CG2 4Å; F188-V203 HydrophobicContact CZ-CG1 3.86Å; F188-V203 HydrophobicContact CZ-CG2 4.18Å; V192-V203 HydrophobicContact CG1-CG2 3.89Å; V192-V203 HydrophobicContact CG2-CG2 3.85Å; F201-V203 HydrophobicContact CD1-CG2 3.65Å; F201-V203 HydrophobicContact CE1-CG2 3.7Å; F201-V203 PolarHBondContact O-N 3.48Å; V203-P363 HydrophobicContact CG1-CB 3.94Å; V203-A364 WeakPolarHBondContact O-CB 3.37Å; V203-A364 PolarHBondContact O-N 3.47Å
204	K	52.3	Low	72.6	Confident	25 Å²	25	46.5 Å²	46.5	11%	0.109	24%	0.238	C	C	.	.			trans	-103.6	102.6	-177.2	-89.6	177.5	179.4	122.2	0	110.6	E175 F178 N202 G206 P363	E175-K204 HydrophobicContact CG-CD 4.19Å; E175-K204 VanDerWaalsContact OE2-CD 3.24Å; E175-K204 WeakPolarHBondContact OE2-CD 3.38Å; E175-K204 WeakPolarHBondContact OE2-CE 3.14Å; E175-K204 IonicContact OE2-NZ 2.7Å; E175-K204 PolarHBondContact OE2-NZ 2.78Å; F178-K204 HydrophobicContact CD2-CD 4.48Å; F178-K204 VanDerWaalsContact CD2-NZ 3.28Å; N202-K204 PolarHBondContact ND2-O 3.41Å; N202-K204 VanDerWaalsContact OD1-C 3.28Å; N202-K204 PolarHBondContact OD1-N 2.87Å; N202-K204 VanDerWaalsContact OD1-N 3.16Å; N202-K204 PolarHBondContact OD1-O 2.88Å; K204-G206 PolarHBondContact O-N 2.9Å; K204-P363 HydrophobicContact CG-CB 3.77Å
205	E	50.4	Low	72.8	Confident	52 Å²	52	44.6 Å²	44.6	24%	0.243	23%	0.227	C	C	.	.			trans	-67.5	70.5	167.2	-71.9	-171.5	153.1	0	0	111.3	R116 A364 R367	R116-E205 VanDerWaalsContact CD-OE2 3.22Å; R116-E205 WeakPolarHBondContact CD-OE2 3.42Å; R116-E205 IonicContact CZ-OE2 3.07Å; R116-E205 IonicContact NE-OE2 3.91Å; R116-E205 IonicContact NH1-OE2 2.77Å; R116-E205 PolarHBondContact NH1-OE2 2.8Å; E205-A364 HydrophobicContact CB-CB 4.5Å; E205-A364 HydrophobicContact CG-CB 4.03Å; E205-R367 PolarHBondContact O-NH1 3.48Å; E205-R367 PolarHBondContact O-NH2 3.23Å
206	G	47.1	Very low	73	Confident	37 Å²	37	45 Å²	45	38%	0.381	23%	0.229	S	C	.	.			trans	-127.8	154.1	-178.6	0	0	0	0	0	112.4	K204 T208	K204-G206 PolarHBondContact O-N 2.9Å; G206-T208 VanDerWaalsContact C-N 3.34Å; G206-T208 PolarHBondContact O-N 3.03Å
207	C	45.8	Very low	73.2	Confident	125 Å²	125	49.7 Å²	49.7	85%	0.845	25%	0.254	S	S	*	.	S	Bend	trans	-75.4	74.7	-173.9	-71.5	0	0	0	0	113.1
208	T	61.5	Low	73.5	Confident	60 Å²	60	51.9 Å²	51.9	37%	0.368	27%	0.267	S	S	.	.			trans	-129.3	65.1	175.2	53.6	0	0	0	0	112.3	G206 Y210 R211 L212	G206-T208 VanDerWaalsContact C-N 3.34Å; G206-T208 PolarHBondContact O-N 3.03Å; T208-Y210 PolarHBondContact O-N 3.06Å; T208-R211 HydrophobicContact CG2-CG 4.3Å; T208-R211 PolarHBondContact O-N 3.25Å; T208-R211 WeakPolarHBondContact OG1-CD 3.18Å; T208-L212 PolarHBondContact O-N 3.42Å
209	R	70.4	Confident	73.8	Confident	152 Å²	152	51.2 Å²	51.2	57%	0.574	26%	0.264	S	S	*	.	H	α-helix	trans	-47.2	-36.7	172	-67.5	178.4	177.4	168.7	-2.5	112	L212 S213 N271	R209-L212 PolarHBondContact O-N 2.93Å; R209-S213 PolarHBondContact O-N 3.35Å; R209-S213 PolarHBondContact O-OG 2.89Å; R209-N271 PolarHBondContact NH2-O 3.06Å
210	Y	74.8	Confident	74.2	Confident	179 Å²	179	54.2 Å²	54.2	70%	0.702	28%	0.28	S	S	*	.	H	α-helix	trans	-64.4	-41.5	176.7	-173.6	-119.4	0	0	0	114	T208 L212 S213 I214	T208-Y210 PolarHBondContact O-N 3.06Å; Y210-L212 PolarHBondContact O-N 3.22Å; Y210-S213 PolarHBondContact O-N 3.07Å; Y210-I214 HydrophobicContact CD1-CD1 3.61Å; Y210-I214 HydrophobicContact CD1-CG1 4.5Å; Y210-I214 HydrophobicContact CD2-CD1 4.42Å; Y210-I214 HydrophobicContact CD2-CG1 4.48Å; Y210-I214 HydrophobicContact CE1-CD1 3.29Å; Y210-I214 HydrophobicContact CE1-CG1 4.21Å; Y210-I214 HydrophobicContact CE2-CD1 4.14Å; Y210-I214 HydrophobicContact CE2-CG1 4.18Å; Y210-I214 HydrophobicContact CG-CD1 4.17Å; Y210-I214 WeakPolarHBondContact O-CG1 3.35Å; Y210-I214 PolarHBondContact O-N 3.3Å
211	R	80.9	Confident	74.8	Confident	78 Å²	78	57.3 Å²	57.3	29%	0.294	30%	0.3	S	S	.	.	H	α-helix	trans	-63.6	-42.3	176.7	-70.4	-176.1	-174.5	-171	-5.8	111.3	C174 W200 T208 I214 Y215	C174-R211 VanDerWaalsContact O-CZ 3.23Å; C174-R211 PolarHBondContact O-NH1 3.05Å; C174-R211 PolarHBondContact O-NH2 3.18Å; W200-R211 HydrophobicContact CH2-CB 4.45Å; T208-R211 HydrophobicContact CG2-CG 4.3Å; T208-R211 PolarHBondContact O-N 3.25Å; T208-R211 WeakPolarHBondContact OG1-CD 3.18Å; R211-I214 PolarHBondContact O-N 3.4Å; R211-Y215 PolarHBondContact O-N 2.92Å
212	L	82.4	Confident	75.9	Confident	15 Å²	15	58.3 Å²	58.3	8%	0.079	31%	0.305	C	S	.	.	H	α-helix	trans	-59	-48.3	173.5	-173.1	74.6	0	0	0	111.2	W200 T208 R209 Y210 Y215 Y216 M261 Y265	W200-L212 HydrophobicContact CD2-CD1 3.97Å; W200-L212 HydrophobicContact CG-CD1 3.98Å; W200-L212 HydrophobicContact CZ2-CD1 4.09Å; W200-L212 VanDerWaalsContact NE1-CD1 3.29Å; T208-L212 PolarHBondContact O-N 3.42Å; R209-L212 PolarHBondContact O-N 2.93Å; Y210-L212 PolarHBondContact O-N 3.22Å; L212-Y215 PolarHBondContact O-N 2.99Å; L212-Y216 HydrophobicContact CD1-CD2 4.12Å; L212-Y216 HydrophobicContact CD1-CE2 3.72Å; L212-Y216 HydrophobicContact CG-CD2 4.13Å; L212-Y216 HydrophobicContact CG-CE2 4.19Å; L212-Y216 WeakPolarHBondContact O-CD2 3.26Å; L212-Y216 PolarHBondContact O-N 3.04Å; L212-Y216 VanDerWaalsContact O-N 3.08Å; L212-M261 HydrophobicContact CD2-CE 4.4Å; L212-M261 HydrophobicContact CD2-SD 3.9Å; L212-M261 HydrophobicContact CG-SD 4.2Å; L212-Y265 HydrophobicContact CD2-CD2 4.28Å; L212-Y265 HydrophobicContact CD2-CE2 3.54Å
213	S	84	Confident	77.2	Confident	67 Å²	67	56.3 Å²	56.3	47%	0.469	30%	0.295	S	S	.	.	H	α-helix	trans	-63.1	-41.3	178	-65.6	0	0	0	0	113.2	R209 Y210 Y216 L217	R209-S213 PolarHBondContact O-N 3.35Å; R209-S213 PolarHBondContact O-OG 2.89Å; Y210-S213 PolarHBondContact O-N 3.07Å; S213-Y216 PolarHBondContact O-N 2.66Å; S213-L217 VanDerWaalsContact O-CB 3.31Å; S213-L217 WeakPolarHBondContact O-CB 3.43Å; S213-L217 PolarHBondContact O-N 3.18Å
214	I	87.8	Confident	79	Confident	32 Å²	32	57.9 Å²	57.9	16%	0.164	31%	0.307	C	S	.	.	H	α-helix	trans	-60.3	-48.1	175.1	-69.3	160.7	0	0	0	110.3	W170 Y210 R211 Y216 L217 V218	W170-I214 HydrophobicContact CH2-CD1 4.1Å; W170-I214 HydrophobicContact CH2-CG2 3.72Å; W170-I214 HydrophobicContact CZ2-CB 4.4Å; W170-I214 HydrophobicContact CZ2-CD1 4.13Å; W170-I214 HydrophobicContact CZ2-CG2 3.8Å; Y210-I214 HydrophobicContact CD1-CD1 3.61Å; Y210-I214 HydrophobicContact CD1-CG1 4.5Å; Y210-I214 HydrophobicContact CD2-CD1 4.42Å; Y210-I214 HydrophobicContact CD2-CG1 4.48Å; Y210-I214 HydrophobicContact CE1-CD1 3.29Å; Y210-I214 HydrophobicContact CE1-CG1 4.21Å; Y210-I214 HydrophobicContact CE2-CD1 4.14Å; Y210-I214 HydrophobicContact CE2-CG1 4.18Å; Y210-I214 HydrophobicContact CG-CD1 4.17Å; Y210-I214 WeakPolarHBondContact O-CG1 3.35Å; Y210-I214 PolarHBondContact O-N 3.3Å; R211-I214 PolarHBondContact O-N 3.4Å; I214-Y216 PolarHBondContact O-N 3.4Å; I214-L217 WeakPolarHBondContact O-CB 3.24Å; I214-L217 PolarHBondContact O-N 3.09Å; I214-L217 VanDerWaalsContact O-N 3.16Å; I214-V218 HydrophobicContact CG2-CG2 4.18Å; I214-V218 WeakPolarHBondContact O-CG2 3.1Å; I214-V218 PolarHBondContact O-N 2.84Å
215	Y	88.4	Confident	80.9	Confident	10 Å²	10	60 Å²	60	4%	0.039	32%	0.322	C	S	.	.	H	α-helix	trans	-57.9	-50.9	179.6	174.3	-93.3	0	0	0	111.7	M167 Y196 S199 W200 R211 L212 L217 V218 I219	M167-Y215 HydrophobicContact CE-CD2 4.18Å; M167-Y215 HydrophobicContact CE-CE2 4.14Å; M167-Y215 HydrophobicContact SD-CD2 4.23Å; M167-Y215 HydrophobicContact SD-CE2 4.21Å; Y196-Y215 AromaticContact CD1-CD2 4Å; Y196-Y215 HydrophobicContact CD1-CD2 4Å; Y196-Y215 AromaticContact CD1-CE2 3.76Å; Y196-Y215 HydrophobicContact CD1-CE2 3.76Å; Y196-Y215 HydrophobicContact CE1-CD2 4.31Å; Y196-Y215 HydrophobicContact CE1-CE2 4.41Å; Y196-Y215 HydrophobicContact CG-CE2 4.38Å; Y196-Y215 PolarHBondContact O-OH 3.29Å; S199-Y215 PolarHBondContact O-OH 3.48Å; W200-Y215 HydrophobicContact CB-CD1 3.91Å; W200-Y215 HydrophobicContact CB-CE1 3.58Å; W200-Y215 HydrophobicContact CD2-CD1 4.12Å; W200-Y215 HydrophobicContact CD2-CG 4.27Å; W200-Y215 AromaticContact CE3-CD1 3.51Å; W200-Y215 HydrophobicContact CE3-CD1 3.51Å; W200-Y215 AromaticContact CE3-CD2 3.62Å; W200-Y215 HydrophobicContact CE3-CD2 3.62Å; W200-Y215 HydrophobicContact CE3-CE1 4.08Å; W200-Y215 HydrophobicContact CE3-CE2 4.16Å; W200-Y215 AromaticContact CE3-CG 3.25Å; W200-Y215 HydrophobicContact CE3-CG 3.25Å; W200-Y215 HydrophobicContact CG-CD1 4.33Å; W200-Y215 HydrophobicContact CG-CE1 4.44Å; W200-Y215 VanDerWaalsContact CZ3-CB 3.46Å; W200-Y215 HydrophobicContact CZ3-CD1 4.32Å; W200-Y215 AromaticContact CZ3-CD2 3.94Å; W200-Y215 HydrophobicContact CZ3-CD2 3.94Å; W200-Y215 AromaticContact CZ3-CG 3.65Å; W200-Y215 HydrophobicContact CZ3-CG 3.65Å; W200-Y215 PolarHBondContact N-OH 3Å; R211-Y215 PolarHBondContact O-N 2.92Å; L212-Y215 PolarHBondContact O-N 2.99Å; Y215-L217 VanDerWaalsContact C-N 3.26Å; Y215-L217 PolarHBondContact O-N 3.01Å; Y215-V218 PolarHBondContact O-N 3.3Å; Y215-V218 VanDerWaalsContact O-N 3.17Å; Y215-I219 HydrophobicContact CD1-CG1 4.08Å; Y215-I219 HydrophobicContact CD2-CG1 4.28Å; Y215-I219 HydrophobicContact CE1-CD1 4.42Å; Y215-I219 HydrophobicContact CE1-CG1 3.62Å; Y215-I219 HydrophobicContact CE2-CD1 3.95Å; Y215-I219 HydrophobicContact CE2-CG1 3.86Å; Y215-I219 HydrophobicContact CG-CG1 4.39Å; Y215-I219 WeakPolarHBondContact O-CG1 3.2Å; Y215-I219 PolarHBondContact O-N 3.47Å
216	Y	89.8	Confident	83	Confident	12 Å²	12	57.6 Å²	57.6	5%	0.047	31%	0.312	C	S	.	.	H	α-helix	trans	-65.3	-28.7	178.7	-80.1	-71.1	0	0	0	113.2	W133 T137 W200 L212 S213 I214 L220 F254 M261	W133-Y216 AromaticContact CZ2-CE2 3.93Å; W133-Y216 HydrophobicContact CZ2-CE2 3.93Å; W133-Y216 AromaticContact CZ2-CZ 3.93Å; W133-Y216 VanDerWaalsContact CZ2-OH 3.3Å; W133-Y216 WeakPolarHBondContact CZ2-OH 3.06Å; W133-Y216 AromaticContact NE1-CZ 3.56Å; W133-Y216 PolarHBondContact NE1-OH 3.49Å; T137-Y216 HydrophobicContact CG2-CE1 3.84Å; W200-Y216 HydrophobicContact CB-CE2 4.21Å; W200-Y216 HydrophobicContact CG-CE2 4.46Å; L212-Y216 HydrophobicContact CD1-CD2 4.12Å; L212-Y216 HydrophobicContact CD1-CE2 3.72Å; L212-Y216 HydrophobicContact CG-CD2 4.13Å; L212-Y216 HydrophobicContact CG-CE2 4.19Å; L212-Y216 WeakPolarHBondContact O-CD2 3.26Å; L212-Y216 PolarHBondContact O-N 3.04Å; L212-Y216 VanDerWaalsContact O-N 3.08Å; S213-Y216 PolarHBondContact O-N 2.66Å; I214-Y216 PolarHBondContact O-N 3.4Å; Y216-L220 VanDerWaalsContact O-CB 3.23Å; Y216-L220 WeakPolarHBondContact O-CB 3.3Å; Y216-L220 PolarHBondContact O-N 3.49Å; Y216-F254 HydrophobicContact CD1-CE2 4.28Å; Y216-F254 HydrophobicContact CD1-CZ 4.02Å; Y216-M261 HydrophobicContact CD2-SD 3.68Å; Y216-M261 HydrophobicContact CE2-SD 3.62Å; Y216-M261 HydrophobicContact CG-SD 4.44Å
217	L	91.4	Very high	85.1	Confident	105 Å²	105	56 Å²	56	55%	0.55	29%	0.294	S	S	.	.	H	α-helix	trans	-68.4	-44.8	171.5	-175.1	66.7	0	0	0	111.9	S213 I214 Y215 L220 V221	S213-L217 VanDerWaalsContact O-CB 3.31Å; S213-L217 WeakPolarHBondContact O-CB 3.43Å; S213-L217 PolarHBondContact O-N 3.18Å; I214-L217 WeakPolarHBondContact O-CB 3.24Å; I214-L217 PolarHBondContact O-N 3.09Å; I214-L217 VanDerWaalsContact O-N 3.16Å; Y215-L217 VanDerWaalsContact C-N 3.26Å; Y215-L217 PolarHBondContact O-N 3.01Å; L217-L220 PolarHBondContact O-N 3.11Å; L217-V221 WeakPolarHBondContact O-CG2 3.14Å; L217-V221 PolarHBondContact O-N 2.73Å
218	V	92.1	Very high	87.2	Confident	52 Å²	52	52.3 Å²	52.3	32%	0.315	27%	0.273	S	S	.	.	H	α-helix	trans	-61	-48.7	176	171	0	0	0	0	110.4	M167 I214 Y215 L220 V221 E222	M167-V218 HydrophobicContact CE-CG1 3.8Å; I214-V218 HydrophobicContact CG2-CG2 4.18Å; I214-V218 WeakPolarHBondContact O-CG2 3.1Å; I214-V218 PolarHBondContact O-N 2.84Å; Y215-V218 PolarHBondContact O-N 3.3Å; Y215-V218 VanDerWaalsContact O-N 3.17Å; V218-L220 VanDerWaalsContact C-N 3.31Å; V218-L220 PolarHBondContact O-N 3.41Å; V218-V221 PolarHBondContact O-N 3.34Å; V218-E222 HydrophobicContact CG1-CG 4.39Å; V218-E222 WeakPolarHBondContact O-CB 3.31Å; V218-E222 WeakPolarHBondContact O-CG 3.49Å; V218-E222 PolarHBondContact O-N 3.36Å
219	I	91.6	Very high	88.6	Confident	6 Å²	6	52.6 Å²	52.6	3%	0.031	27%	0.272	C	S	.	.	H	α-helix	trans	-62.8	-36.8	177.4	-60.7	-62.4	0	0	0	111.7	M167 Y215 N223 F254	M167-I219 HydrophobicContact CE-CD1 4.31Å; Y215-I219 HydrophobicContact CD1-CG1 4.08Å; Y215-I219 HydrophobicContact CD2-CG1 4.28Å; Y215-I219 HydrophobicContact CE1-CD1 4.42Å; Y215-I219 HydrophobicContact CE1-CG1 3.62Å; Y215-I219 HydrophobicContact CE2-CD1 3.95Å; Y215-I219 HydrophobicContact CE2-CG1 3.86Å; Y215-I219 HydrophobicContact CG-CG1 4.39Å; Y215-I219 WeakPolarHBondContact O-CG1 3.2Å; Y215-I219 PolarHBondContact O-N 3.47Å; I219-N223 VanDerWaalsContact O-CB 3.25Å; I219-N223 WeakPolarHBondContact O-CB 3.25Å; I219-N223 PolarHBondContact O-N 2.88Å; I219-N223 PolarHBondContact O-ND2 3.4Å; I219-N223 PolarHBondContact O-OD1 2.94Å; I219-F254 HydrophobicContact CB-CE2 4.45Å; I219-F254 HydrophobicContact CG2-CE2 3.77Å; I219-F254 HydrophobicContact CG2-CZ 4.38Å
220	L	92.9	Very high	89.5	Confident	64 Å²	64	45.8 Å²	45.8	34%	0.335	25%	0.246	S	C	.	.	H	α-helix	trans	-63.4	-48.4	173.9	175.5	60.2	0	0	0	111.7	Y216 L217 V218 N223 A224 F254	Y216-L220 VanDerWaalsContact O-CB 3.23Å; Y216-L220 WeakPolarHBondContact O-CB 3.3Å; Y216-L220 PolarHBondContact O-N 3.49Å; L217-L220 PolarHBondContact O-N 3.11Å; V218-L220 VanDerWaalsContact C-N 3.31Å; V218-L220 PolarHBondContact O-N 3.41Å; L220-N223 PolarHBondContact O-N 3.22Å; L220-A224 WeakPolarHBondContact O-CB 3.36Å; L220-A224 PolarHBondContact O-N 3.47Å; L220-F254 HydrophobicContact CB-CE1 3.7Å; L220-F254 HydrophobicContact CB-CZ 3.94Å; L220-F254 HydrophobicContact CD1-CD1 3.82Å; L220-F254 HydrophobicContact CD1-CE1 3.77Å; L220-F254 HydrophobicContact CD2-CE1 4.5Å; L220-F254 HydrophobicContact CG-CE1 4.18Å
221	V	94.4	Very high	90	Very high	81 Å²	81	43.2 Å²	43.2	49%	0.491	24%	0.236	S	C	.	.	H	α-helix	trans	-61.5	-45.8	178.8	168.8	0	0	0	0	110.5	L217 V218 A224 T225	L217-V221 WeakPolarHBondContact O-CG2 3.14Å; L217-V221 PolarHBondContact O-N 2.73Å; V218-V221 PolarHBondContact O-N 3.34Å; V221-A224 WeakPolarHBondContact O-CB 3.4Å; V221-A224 PolarHBondContact O-N 3.48Å; V221-T225 HydrophobicContact CG1-CG2 4.43Å; V221-T225 WeakPolarHBondContact O-CG2 3.24Å; V221-T225 PolarHBondContact O-N 3.49Å; V221-T225 PolarHBondContact O-OG1 2.9Å
222	E	93.6	Very high	90.2	Very high	26 Å²	26	45.6 Å²	45.6	12%	0.121	25%	0.254	C	S	.	.	H	α-helix	trans	-64.9	-43.1	176.6	-72.2	178.2	161.7	0	0	112.9	R141 H163 V218 A224 T225 L226	R141-E222 IonicContact CZ-OE2 2.82Å; R141-E222 VanDerWaalsContact CZ-OE2 3.24Å; R141-E222 IonicContact NH1-OE2 3.2Å; R141-E222 PolarHBondContact NH1-OE2 2.92Å; R141-E222 IonicContact NH2-OE2 3.95Å; R141-E222 PolarHBondContact NH2-OE2 2.9Å; H163-E222 VanDerWaalsContact CE1-CD 3.49Å; H163-E222 IonicContact CE1-OE1 2.73Å; H163-E222 PolarHBondContact CE1-OE1 3.37Å; H163-E222 IonicContact CE1-OE2 3.22Å; H163-E222 PolarHBondContact CE1-OE2 2.97Å; H163-E222 IonicContact CG-OE1 3.42Å; H163-E222 VanDerWaalsContact ND1-CD 3.31Å; H163-E222 IonicContact ND1-OE1 3.32Å; H163-E222 PolarHBondContact ND1-OE1 3.5Å; H163-E222 IonicContact ND1-OE2 2.71Å; H163-E222 PolarHBondContact ND1-OE2 3.19Å; V218-E222 HydrophobicContact CG1-CG 4.39Å; V218-E222 WeakPolarHBondContact O-CB 3.31Å; V218-E222 WeakPolarHBondContact O-CG 3.49Å; V218-E222 PolarHBondContact O-N 3.36Å; E222-A224 PolarHBondContact O-N 3.03Å; E222-T225 WeakPolarHBondContact CA-OG1 3.48Å; E222-T225 PolarHBondContact O-N 3.3Å; E222-T225 PolarHBondContact O-OG1 2.92Å; E222-T225 VanDerWaalsContact O-OG1 3.11Å; E222-L226 WeakPolarHBondContact O-CB 3.46Å; E222-L226 VanDerWaalsContact O-CG 3.23Å; E222-L226 WeakPolarHBondContact O-CG 3.45Å; E222-L226 PolarHBondContact O-N 3.41Å
223	N	93.4	Very high	90.3	Very high	2 Å²	2	52.1 Å²	52.1	1%	0.011	28%	0.279	C	S	.	.	H	α-helix	trans	-63	-36.1	176.7	-71.1	-8	0	0	0	110.6	R141 T144 I219 L220 S227	R141-N223 WeakPolarHBondContact CD-OD1 3.49Å; R141-N223 PolarHBondContact NH1-OD1 3.33Å; T144-N223 HydrophobicContact CG2-CB 4.41Å; I219-N223 VanDerWaalsContact O-CB 3.25Å; I219-N223 WeakPolarHBondContact O-CB 3.25Å; I219-N223 PolarHBondContact O-N 2.88Å; I219-N223 PolarHBondContact O-ND2 3.4Å; I219-N223 PolarHBondContact O-OD1 2.94Å; L220-N223 PolarHBondContact O-N 3.22Å; N223-S227 WeakPolarHBondContact O-CB 3.42Å; N223-S227 PolarHBondContact O-N 3.42Å; N223-S227 VanDerWaalsContact O-N 3.08Å; N223-S227 PolarHBondContact O-OG 3.4Å
224	A	93.6	Very high	89.9	Confident	35 Å²	35	50.2 Å²	50.2	29%	0.289	26%	0.261	S	S	.	.	H	α-helix	trans	-68.6	-45.2	174.4	0	0	0	0	0	112.6	L220 V221 E222 S227 A228 F251	L220-A224 WeakPolarHBondContact O-CB 3.36Å; L220-A224 PolarHBondContact O-N 3.47Å; V221-A224 WeakPolarHBondContact O-CB 3.4Å; V221-A224 PolarHBondContact O-N 3.48Å; E222-A224 PolarHBondContact O-N 3.03Å; A224-S227 PolarHBondContact O-N 3.21Å; A224-A228 WeakPolarHBondContact O-CB 3.5Å; A224-A228 PolarHBondContact O-N 3.04Å; A224-F251 HydrophobicContact CB-CE1 4.15Å; A224-F251 HydrophobicContact CB-CZ 4.28Å
225	T	93.5	Very high	89.1	Confident	69 Å²	69	53.5 Å²	53.5	42%	0.423	28%	0.283	S	S	.	.	H	α-helix	trans	-67.9	-43.3	179.7	55.3	0	0	0	0	112	V221 E222 A228 L229	V221-T225 HydrophobicContact CG1-CG2 4.43Å; V221-T225 WeakPolarHBondContact O-CG2 3.24Å; V221-T225 PolarHBondContact O-N 3.49Å; V221-T225 PolarHBondContact O-OG1 2.9Å; E222-T225 WeakPolarHBondContact CA-OG1 3.48Å; E222-T225 PolarHBondContact O-N 3.3Å; E222-T225 PolarHBondContact O-OG1 2.92Å; E222-T225 VanDerWaalsContact O-OG1 3.11Å; T225-A228 PolarHBondContact O-N 3.41Å; T225-L229 WeakPolarHBondContact O-CB 3.39Å; T225-L229 VanDerWaalsContact O-CG 3.25Å; T225-L229 WeakPolarHBondContact O-CG 3.4Å; T225-L229 PolarHBondContact O-N 3.03Å
226	L	92.6	Very high	87.8	Confident	3 Å²	3	56.8 Å²	56.8	2%	0.016	31%	0.305	C	S	.	.	H	α-helix	trans	-62.6	-42.7	175.4	-67.5	179.1	0	0	0	111.7	T144 F145 F148 F159 E222 W230	T144-L226 HydrophobicContact CG2-CB 3.61Å; T144-L226 HydrophobicContact CG2-CD1 4.18Å; F145-L226 HydrophobicContact CD1-CD1 3.75Å; F145-L226 HydrophobicContact CE1-CD1 3.77Å; F148-L226 HydrophobicContact CB-CB 4.35Å; F148-L226 HydrophobicContact CB-CD2 4.39Å; F148-L226 HydrophobicContact CD1-CD2 3.98Å; F148-L226 HydrophobicContact CD2-CB 4.38Å; F148-L226 HydrophobicContact CD2-CD2 3.73Å; F148-L226 HydrophobicContact CE1-CD2 4.14Å; F148-L226 HydrophobicContact CE2-CD2 3.93Å; F148-L226 HydrophobicContact CG-CB 4.48Å; F148-L226 HydrophobicContact CG-CD2 3.76Å; F148-L226 HydrophobicContact CZ-CD2 4.12Å; F159-L226 HydrophobicContact CD2-CD2 4.22Å; F159-L226 HydrophobicContact CE1-CD1 3.9Å; F159-L226 HydrophobicContact CE2-CD1 4.5Å; F159-L226 HydrophobicContact CE2-CD2 4.13Å; F159-L226 HydrophobicContact CG-CD2 4.44Å; F159-L226 HydrophobicContact CZ-CD1 3.87Å; F159-L226 HydrophobicContact CZ-CD2 4.29Å; F159-L226 HydrophobicContact CZ-CG 4.37Å; E222-L226 WeakPolarHBondContact O-CB 3.46Å; E222-L226 VanDerWaalsContact O-CG 3.23Å; E222-L226 WeakPolarHBondContact O-CG 3.45Å; E222-L226 PolarHBondContact O-N 3.41Å; L226-W230 WeakPolarHBondContact O-CB 3.43Å; L226-W230 PolarHBondContact O-N 3.33Å
227	S	91.3	Very high	86.2	Confident	3 Å²	3	66 Å²	66	2%	0.021	35%	0.345	C	S	.	.	H	α-helix	trans	-67	-37.7	176.1	-62	0	0	0	0	112.6	N223 A224 Y231	N223-S227 WeakPolarHBondContact O-CB 3.42Å; N223-S227 PolarHBondContact O-N 3.42Å; N223-S227 VanDerWaalsContact O-N 3.08Å; N223-S227 PolarHBondContact O-OG 3.4Å; A224-S227 PolarHBondContact O-N 3.21Å; S227-Y231 WeakPolarHBondContact O-CB 3.38Å; S227-Y231 PolarHBondContact O-N 3.46Å
228	A	90.4	Very high	84.5	Confident	47 Å²	47	66.4 Å²	66.4	39%	0.388	35%	0.353	S	S	.	.	H	α-helix	trans	-69.3	-43	176.2	0	0	0	0	0	111.9	A224 T225 W230 Y231 L232	A224-A228 WeakPolarHBondContact O-CB 3.5Å; A224-A228 PolarHBondContact O-N 3.04Å; T225-A228 PolarHBondContact O-N 3.41Å; A228-W230 VanDerWaalsContact C-N 3.34Å; A228-W230 PolarHBondContact O-N 3.44Å; A228-Y231 PolarHBondContact O-N 3.01Å; A228-L232 WeakPolarHBondContact O-CB 3.39Å; A228-L232 VanDerWaalsContact O-CG 3.26Å; A228-L232 WeakPolarHBondContact O-CG 3.31Å; A228-L232 PolarHBondContact O-N 2.73Å
229	L	90.5	Very high	83.1	Confident	66 Å²	66	64.9 Å²	64.9	35%	0.346	34%	0.343	S	S	.	.	H	α-helix	trans	-60.2	-43.7	173.3	-74.1	168.5	0	0	0	111.2	F148 T225 Y231 L232 Y233	F148-L229 HydrophobicContact CD2-CB 4.29Å; F148-L229 HydrophobicContact CE2-CB 4.02Å; F148-L229 HydrophobicContact CE2-CD1 3.96Å; T225-L229 WeakPolarHBondContact O-CB 3.39Å; T225-L229 VanDerWaalsContact O-CG 3.25Å; T225-L229 WeakPolarHBondContact O-CG 3.4Å; T225-L229 PolarHBondContact O-N 3.03Å; L229-Y231 PolarHBondContact O-N 3.31Å; L229-L232 PolarHBondContact O-N 3.29Å; L229-Y233 HydrophobicContact CD2-CD2 4.33Å; L229-Y233 HydrophobicContact CD2-CE2 3.99Å; L229-Y233 WeakPolarHBondContact O-CD2 3.47Å; L229-Y233 PolarHBondContact O-N 3.06Å; L229-Y233 VanDerWaalsContact O-N 3.14Å
230	W	89.3	Confident	81.8	Confident	10 Å²	10	69.5 Å²	69.5	4%	0.038	37%	0.368	C	S	.	.	H	α-helix	trans	-59.8	-44.9	172.8	177.1	81.3	0	0	0	112.1	L147 L226 A228 R234 A243 L247	L147-W230 HydrophobicContact CB-CD2 4.18Å; L147-W230 HydrophobicContact CB-CG 3.98Å; L147-W230 HydrophobicContact CD1-CD2 4.17Å; L147-W230 HydrophobicContact CD1-CE3 4.19Å; L147-W230 HydrophobicContact CD1-CH2 4.46Å; L147-W230 HydrophobicContact CD1-CZ2 4.47Å; L147-W230 HydrophobicContact CD1-CZ3 4.34Å; L147-W230 HydrophobicContact CD2-CH2 4.42Å; L147-W230 HydrophobicContact CD2-CZ2 3.83Å; L147-W230 PolarHBondContact O-NE1 2.89Å; L226-W230 WeakPolarHBondContact O-CB 3.43Å; L226-W230 PolarHBondContact O-N 3.33Å; A228-W230 VanDerWaalsContact C-N 3.34Å; A228-W230 PolarHBondContact O-N 3.44Å; W230-R234 WeakPolarHBondContact O-CB 3.4Å; W230-R234 PolarHBondContact O-N 2.85Å; W230-A243 HydrophobicContact CZ3-CB 4.48Å; W230-L247 HydrophobicContact CE3-CD2 4.49Å; W230-L247 HydrophobicContact CZ3-CG 4.5Å
231	Y	86.1	Confident	80.9	Confident	125 Å²	125	71.1 Å²	71.1	49%	0.49	39%	0.391	S	S	.	.	H	α-helix	trans	-65	-40.4	-179.9	-176	-100.3	0	0	0	112.9	S227 A228 L229 A243 L247	S227-Y231 WeakPolarHBondContact O-CB 3.38Å; S227-Y231 PolarHBondContact O-N 3.46Å; A228-Y231 PolarHBondContact O-N 3.01Å; L229-Y231 PolarHBondContact O-N 3.31Å; Y231-A243 HydrophobicContact CD2-CB 4.37Å; Y231-A243 HydrophobicContact CE2-CB 4.16Å; Y231-L247 HydrophobicContact CD2-CD1 3.76Å; Y231-L247 HydrophobicContact CE2-CD1 4.29Å; Y231-L247 HydrophobicContact CG-CD1 4.33Å
232	L	85.9	Confident	79.9	Confident	127 Å²	127	72.4 Å²	72.4	67%	0.665	39%	0.39	S	S	*	.	H	α-helix	trans	-73.3	-39	-177	-72.2	169.8	0	0	0	113.9	A228 L229	A228-L232 WeakPolarHBondContact O-CB 3.39Å; A228-L232 VanDerWaalsContact O-CG 3.26Å; A228-L232 WeakPolarHBondContact O-CG 3.31Å; A228-L232 PolarHBondContact O-N 2.73Å; L229-L232 PolarHBondContact O-N 3.29Å
233	Y	84.4	Confident	79.3	Confident	153 Å²	153	71.3 Å²	71.3	60%	0.6	39%	0.385	S	S	*	.	S	Bend	trans	-97.4	7.7	-173.9	-73.3	-79	0	0	0	114.6	F152 L229	F152-Y233 AromaticContact CE2-CD2 3.93Å; F152-Y233 HydrophobicContact CE2-CD2 3.93Å; F152-Y233 AromaticContact CE2-CG 3.95Å; F152-Y233 HydrophobicContact CE2-CG 3.95Å; F152-Y233 HydrophobicContact CZ-CD1 4.06Å; F152-Y233 AromaticContact CZ-CD2 3.79Å; F152-Y233 HydrophobicContact CZ-CD2 3.79Å; F152-Y233 AromaticContact CZ-CG 3.52Å; F152-Y233 HydrophobicContact CZ-CG 3.52Å; L229-Y233 HydrophobicContact CD2-CD2 4.33Å; L229-Y233 HydrophobicContact CD2-CE2 3.99Å; L229-Y233 WeakPolarHBondContact O-CD2 3.47Å; L229-Y233 PolarHBondContact O-N 3.06Å; L229-Y233 VanDerWaalsContact O-N 3.14Å
234	R	75.1	Confident	78.9	Confident	26 Å²	26	76 Å²	76	10%	0.098	41%	0.414	C	S	.	.	S	Bend	trans	-82.7	146.4	-178.5	142.1	-167.1	148.2	119.4	7.4	111.8	W230 P236 T239 D240 A243	W230-R234 WeakPolarHBondContact O-CB 3.4Å; W230-R234 PolarHBondContact O-N 2.85Å; R234-P236 WeakPolarHBondContact O-CD 3.11Å; R234-T239 VanDerWaalsContact CZ-O 3.28Å; R234-T239 VanDerWaalsContact NH1-CB 3.26Å; R234-T239 PolarHBondContact NH1-O 2.94Å; R234-T239 PolarHBondContact NH2-O 2.98Å; R234-D240 IonicContact CZ-OD1 2.98Å; R234-D240 IonicContact NH2-OD1 3.2Å; R234-D240 PolarHBondContact NH2-OD1 2.65Å; R234-A243 VanDerWaalsContact NH2-CB 3.29Å
235	T	70.3	Confident	78.6	Confident	101 Å²	101	77.6 Å²	77.6	62%	0.62	42%	0.421	S	S	*	.			trans	-71.6	123	174.9	-44.5	0	0	0	0	111.2	T239	T235-T239 PolarHBondContact O-OG1 2.9Å
236	P	61.2	Low	78.3	Confident	80 Å²	80	74.8 Å²	74.8	52%	0.519	41%	0.405	S	S	.	.	G	3₁₀ helix	trans	-66.6	-42.5	-173.3	-24.4	34.3	0	0	0	114.5	R234 T238 T239	R234-P236 WeakPolarHBondContact O-CD 3.11Å; P236-T238 VanDerWaalsContact C-N 3.26Å; P236-T238 PolarHBondContact O-N 3.08Å; P236-T239 PolarHBondContact O-N 3.29Å
237	K	55.8	Low	78.2	Confident	204 Å²	204	76.2 Å²	76.2	89%	0.887	41%	0.412	S	S	*	.	G	3₁₀ helix	trans	-65	-12.7	-158.6	-71.5	-170.5	174.5	-177.6	0	117.4
238	T	56	Low	78.2	Confident	114 Å²	114	79.8 Å²	79.8	70%	0.699	44%	0.437	S	S	*	.	G	3₁₀ helix	trans	-122.4	-7.9	-174.7	50.9	0	0	0	0	114.3	P236	P236-T238 VanDerWaalsContact C-N 3.26Å; P236-T238 PolarHBondContact O-N 3.08Å
239	T	62.5	Low	78.3	Confident	20 Å²	20	81 Å²	81	12%	0.123	44%	0.439	C	S	.	.	T	Hydrogen-bonded Turn	trans	-128.9	-4.2	-155.6	-24.9	0	0	0	0	113.4	R234 T235 P236 A241 F242 A243	R234-T239 VanDerWaalsContact CZ-O 3.28Å; R234-T239 VanDerWaalsContact NH1-CB 3.26Å; R234-T239 PolarHBondContact NH1-O 2.94Å; R234-T239 PolarHBondContact NH2-O 2.98Å; T235-T239 PolarHBondContact O-OG1 2.9Å; P236-T239 PolarHBondContact O-N 3.29Å; T239-A241 PolarHBondContact O-N 2.86Å; T239-F242 PolarHBondContact O-N 2.9Å; T239-A243 PolarHBondContact O-N 2.86Å; T239-A243 VanDerWaalsContact O-N 3.09Å
240	D	65.9	Low	78.4	Confident	104 Å²	104	77.9 Å²	77.9	56%	0.556	42%	0.423	S	S	*	.	H	α-helix	trans	-59.6	-39.6	-173.7	-75.8	-10.9	0	0	0	114	R234 F242	R234-D240 IonicContact CZ-OD1 2.98Å; R234-D240 IonicContact NH2-OD1 3.2Å; R234-D240 PolarHBondContact NH2-OD1 2.65Å; D240-F242 PolarHBondContact O-N 3.02Å
241	A	72.5	Confident	78.6	Confident	98 Å²	98	81.6 Å²	81.6	81%	0.81	44%	0.439	S	S	*	.	H	α-helix	trans	-63	-23.4	173.1	0	0	0	0	0	114.3	T239 P245	T239-A241 PolarHBondContact O-N 2.86Å; A241-P245 WeakPolarHBondContact O-CD 3.27Å; A241-P245 WeakPolarHBondContact O-CG 3.5Å
242	F	74.8	Confident	79	Confident	108 Å²	108	78.2 Å²	78.2	47%	0.474	43%	0.434	S	S	.	.	H	α-helix	trans	-103.5	-17	-174.7	-168.1	-102.9	0	0	0	114.1	T239 D240 A246	T239-F242 PolarHBondContact O-N 2.9Å; D240-F242 PolarHBondContact O-N 3.02Å; F242-A246 HydrophobicContact CD1-CB 4.31Å; F242-A246 HydrophobicContact CE1-CB 4.08Å; F242-A246 VanDerWaalsContact O-CB 3.29Å; F242-A246 WeakPolarHBondContact O-CB 3.49Å; F242-A246 PolarHBondContact O-N 2.88Å; F242-A246 VanDerWaalsContact O-N 3.14Å
243	A	81.1	Confident	79.4	Confident	2 Å²	2	72.7 Å²	72.7	2%	0.017	41%	0.406	C	S	.	.	H	α-helix	trans	-59.4	-57.6	179.4	0	0	0	0	0	112.4	W230 Y231 R234 T239 A246 L247	W230-A243 HydrophobicContact CZ3-CB 4.48Å; Y231-A243 HydrophobicContact CD2-CB 4.37Å; Y231-A243 HydrophobicContact CE2-CB 4.16Å; R234-A243 VanDerWaalsContact NH2-CB 3.29Å; T239-A243 PolarHBondContact O-N 2.86Å; T239-A243 VanDerWaalsContact O-N 3.09Å; A243-A246 PolarHBondContact O-N 3.31Å; A243-L247 WeakPolarHBondContact O-CG 3.16Å; A243-L247 PolarHBondContact O-N 2.9Å
244	V	84.8	Confident	79.8	Confident	102 Å²	102	65.9 Å²	65.9	62%	0.618	38%	0.38	S	S	*	.	H	α-helix	trans	-66.4	-43	-170.6	-175.3	0	0	0	0	110.8	C248	V244-C248 WeakPolarHBondContact O-CB 3.38Å; V244-C248 PolarHBondContact O-N 3.42Å
245	P	87.4	Confident	80.7	Confident	67 Å²	67	69.7 Å²	69.7	44%	0.435	40%	0.402	S	S	.	.	H	α-helix	trans	-58.5	-45.4	170.1	-26.5	36.2	0	0	0	113.7	A241 C248 V249	A241-P245 WeakPolarHBondContact O-CD 3.27Å; A241-P245 WeakPolarHBondContact O-CG 3.5Å; P245-C248 PolarHBondContact O-N 3.38Å; P245-V249 VanDerWaalsContact O-CG2 3.3Å; P245-V249 WeakPolarHBondContact O-CG2 3.35Å; P245-V249 PolarHBondContact O-N 2.9Å
246	A	86.3	Confident	81.8	Confident	11 Å²	11	67.4 Å²	67.4	9%	0.091	39%	0.387	C	S	.	.	H	α-helix	trans	-64.6	-45.4	-177.8	0	0	0	0	0	112.5	L147 F242 A243 V249 I250	L147-A246 HydrophobicContact CD1-CB 4.27Å; F242-A246 HydrophobicContact CD1-CB 4.31Å; F242-A246 HydrophobicContact CE1-CB 4.08Å; F242-A246 VanDerWaalsContact O-CB 3.29Å; F242-A246 WeakPolarHBondContact O-CB 3.49Å; F242-A246 PolarHBondContact O-N 2.88Å; F242-A246 VanDerWaalsContact O-N 3.14Å; A243-A246 PolarHBondContact O-N 3.31Å; A246-V249 PolarHBondContact O-N 3.45Å; A246-I250 WeakPolarHBondContact O-CG1 3.27Å; A246-I250 PolarHBondContact O-N 2.94Å
247	L	90.5	Very high	83.2	Confident	32 Å²	32	63.6 Å²	63.6	17%	0.168	36%	0.363	C	S	.	.	H	α-helix	trans	-63.5	-43.3	174.7	-67.4	176.9	0	0	0	111.5	W230 Y231 A243 V249 I250 F251	W230-L247 HydrophobicContact CE3-CD2 4.49Å; W230-L247 HydrophobicContact CZ3-CG 4.5Å; Y231-L247 HydrophobicContact CD2-CD1 3.76Å; Y231-L247 HydrophobicContact CE2-CD1 4.29Å; Y231-L247 HydrophobicContact CG-CD1 4.33Å; A243-L247 WeakPolarHBondContact O-CG 3.16Å; A243-L247 PolarHBondContact O-N 2.9Å; L247-V249 VanDerWaalsContact C-N 3.33Å; L247-V249 PolarHBondContact O-N 3.3Å; L247-I250 PolarHBondContact O-N 2.91Å; L247-F251 VanDerWaalsContact O-CD2 3.22Å; L247-F251 WeakPolarHBondContact O-CD2 3.27Å; L247-F251 PolarHBondContact O-N 3.44Å
248	C	91.3	Very high	84.9	Confident	78 Å²	78	56.1 Å²	56.1	53%	0.527	33%	0.332	S	S	.	.	H	α-helix	trans	-58.7	-44.5	176	-173.5	0	0	0	0	111.4	V244 P245 I250 S252	V244-C248 WeakPolarHBondContact O-CB 3.38Å; V244-C248 PolarHBondContact O-N 3.42Å; P245-C248 PolarHBondContact O-N 3.38Å; C248-I250 PolarHBondContact O-N 2.92Å; C248-S252 WeakPolarHBondContact O-CB 3.42Å; C248-S252 PolarHBondContact O-N 3.02Å; C248-S252 PolarHBondContact O-OG 3.46Å
249	V	91.7	Very high	86.6	Confident	73 Å²	73	54.7 Å²	54.7	44%	0.442	32%	0.323	S	S	.	.	H	α-helix	trans	-61.1	-43.8	175.7	168.4	0	0	0	0	111.7	I143 P245 A246 L247 S252 S253	I143-V249 HydrophobicContact CD1-CG1 4.2Å; P245-V249 VanDerWaalsContact O-CG2 3.3Å; P245-V249 WeakPolarHBondContact O-CG2 3.35Å; P245-V249 PolarHBondContact O-N 2.9Å; A246-V249 PolarHBondContact O-N 3.45Å; L247-V249 VanDerWaalsContact C-N 3.33Å; L247-V249 PolarHBondContact O-N 3.3Å; V249-S252 PolarHBondContact O-OG 3.37Å; V249-S253 WeakPolarHBondContact O-CB 3.47Å; V249-S253 PolarHBondContact O-N 2.67Å; V249-S253 PolarHBondContact O-OG 3.16Å
250	I	93.1	Very high	87.8	Confident	1 Å²	1	56.2 Å²	56.2	1%	0.005	33%	0.328	C	S	.	.	H	α-helix	trans	-61.2	-53.8	178.1	-71.3	164.5	0	0	0	111.4	I143 T144 L147 A246 L247 C248 S253 F254	I143-I250 HydrophobicContact CB-CG1 4.32Å; I143-I250 HydrophobicContact CG2-CD1 4.04Å; I143-I250 HydrophobicContact CG2-CG1 3.79Å; T144-I250 VanDerWaalsContact OG1-CG2 3.3Å; T144-I250 WeakPolarHBondContact OG1-CG2 3.23Å; L147-I250 HydrophobicContact CD1-CD1 3.53Å; A246-I250 WeakPolarHBondContact O-CG1 3.27Å; A246-I250 PolarHBondContact O-N 2.94Å; L247-I250 PolarHBondContact O-N 2.91Å; C248-I250 PolarHBondContact O-N 2.92Å; I250-S253 PolarHBondContact O-OG 3.28Å; I250-S253 VanDerWaalsContact O-OG 3.07Å; I250-F254 WeakPolarHBondContact O-CB 3.46Å; I250-F254 PolarHBondContact O-N 2.89Å
251	F	93.9	Very high	88.7	Confident	87 Å²	87	51.7 Å²	51.7	38%	0.382	30%	0.304	S	S	.	.	H	α-helix	trans	-71.7	-38.4	-175.8	-69.6	-66	0	0	0	112.6	A224 L247 L255	A224-F251 HydrophobicContact CB-CE1 4.15Å; A224-F251 HydrophobicContact CB-CZ 4.28Å; L247-F251 VanDerWaalsContact O-CD2 3.22Å; L247-F251 WeakPolarHBondContact O-CD2 3.27Å; L247-F251 PolarHBondContact O-N 3.44Å; F251-L255 VanDerWaalsContact O-CB 3.26Å; F251-L255 WeakPolarHBondContact O-CB 3.47Å; F251-L255 PolarHBondContact O-N 3.17Å
252	S	94.4	Very high	89.3	Confident	55 Å²	55	51.9 Å²	51.9	39%	0.385	29%	0.29	S	S	.	.	H	α-helix	trans	-68.1	-39.8	177	62.3	0	0	0	0	112.5	C248 V249 T256	C248-S252 WeakPolarHBondContact O-CB 3.42Å; C248-S252 PolarHBondContact O-N 3.02Å; C248-S252 PolarHBondContact O-OG 3.46Å; V249-S252 PolarHBondContact O-OG 3.37Å; S252-T256 WeakPolarHBondContact O-CB 3.45Å; S252-T256 PolarHBondContact O-N 2.88Å; S252-T256 PolarHBondContact O-OG1 3.15Å
253	S	93.9	Very high	89.7	Confident	11 Å²	11	49.4 Å²	49.4	8%	0.077	28%	0.281	C	S	.	.	H	α-helix	trans	-66.5	-44.6	174.8	57.8	0	0	0	0	111.7	F136 A140 V249 I250 L255 T256 G257	F136-S253 WeakPolarHBondContact CB-O 3.22Å; A140-S253 WeakPolarHBondContact CB-OG 3.47Å; V249-S253 WeakPolarHBondContact O-CB 3.47Å; V249-S253 PolarHBondContact O-N 2.67Å; V249-S253 PolarHBondContact O-OG 3.16Å; I250-S253 PolarHBondContact O-OG 3.28Å; I250-S253 VanDerWaalsContact O-OG 3.07Å; S253-L255 PolarHBondContact O-N 3.46Å; S253-T256 PolarHBondContact O-N 3.45Å; S253-G257 PolarHBondContact O-N 3.2Å
254	F	93.5	Very high	89.7	Confident	10 Å²	10	50.5 Å²	50.5	4%	0.044	29%	0.285	C	S	.	.	H	α-helix	trans	-60.9	-46.2	176.2	-170.9	-95	0	0	0	112.4	A140 Y216 I219 L220 I250 T256 G257 L258	A140-F254 HydrophobicContact CB-CB 3.79Å; A140-F254 HydrophobicContact CB-CD2 4.22Å; Y216-F254 HydrophobicContact CD1-CE2 4.28Å; Y216-F254 HydrophobicContact CD1-CZ 4.02Å; I219-F254 HydrophobicContact CB-CE2 4.45Å; I219-F254 HydrophobicContact CG2-CE2 3.77Å; I219-F254 HydrophobicContact CG2-CZ 4.38Å; L220-F254 HydrophobicContact CB-CE1 3.7Å; L220-F254 HydrophobicContact CB-CZ 3.94Å; L220-F254 HydrophobicContact CD1-CD1 3.82Å; L220-F254 HydrophobicContact CD1-CE1 3.77Å; L220-F254 HydrophobicContact CD2-CE1 4.5Å; L220-F254 HydrophobicContact CG-CE1 4.18Å; I250-F254 WeakPolarHBondContact O-CB 3.46Å; I250-F254 PolarHBondContact O-N 2.89Å; F254-T256 PolarHBondContact O-N 2.84Å; F254-G257 PolarHBondContact O-N 3.39Å; F254-L258 PolarHBondContact O-N 2.71Å
255	L	93.9	Very high	89.1	Confident	106 Å²	106	48.7 Å²	48.7	56%	0.555	27%	0.268	S	S	*	.	H	α-helix	trans	-62.1	-41.9	176.5	-178.7	62.8	0	0	0	111.8	F251 S253 G257 L258 V259	F251-L255 VanDerWaalsContact O-CB 3.26Å; F251-L255 WeakPolarHBondContact O-CB 3.47Å; F251-L255 PolarHBondContact O-N 3.17Å; S253-L255 PolarHBondContact O-N 3.46Å; L255-G257 VanDerWaalsContact C-N 3.35Å; L255-G257 PolarHBondContact O-N 3.15Å; L255-L258 WeakPolarHBondContact O-CB 3.36Å; L255-L258 PolarHBondContact O-N 2.73Å; L255-V259 WeakPolarHBondContact O-CG2 3.38Å; L255-V259 PolarHBondContact O-N 3.29Å
256	T	93.4	Very high	88.4	Confident	52 Å²	52	48.5 Å²	48.5	32%	0.319	27%	0.271	S	S	.	.	H	α-helix	trans	-61.3	-44	175.8	-62.9	0	0	0	0	111.1	F136 S252 S253 F254 L258 V259 F260	F136-T256 HydrophobicContact CD1-CG2 4.28Å; F136-T256 HydrophobicContact CD2-CG2 3.73Å; F136-T256 HydrophobicContact CE1-CG2 4.33Å; F136-T256 HydrophobicContact CE2-CG2 3.81Å; F136-T256 HydrophobicContact CG-CG2 4.01Å; F136-T256 HydrophobicContact CZ-CG2 4.11Å; S252-T256 WeakPolarHBondContact O-CB 3.45Å; S252-T256 PolarHBondContact O-N 2.88Å; S252-T256 PolarHBondContact O-OG1 3.15Å; S253-T256 PolarHBondContact O-N 3.45Å; F254-T256 PolarHBondContact O-N 2.84Å; T256-L258 VanDerWaalsContact C-N 3.34Å; T256-L258 PolarHBondContact O-N 3.01Å; T256-V259 PolarHBondContact O-N 3.37Å; T256-F260 HydrophobicContact CG2-CD2 3.76Å; T256-F260 HydrophobicContact CG2-CE2 3.49Å; T256-F260 VanDerWaalsContact CG2-CE2 3.49Å; T256-F260 WeakPolarHBondContact O-CD2 3.38Å; T256-F260 PolarHBondContact O-N 2.9Å
257	G	91.3	Very high	87.5	Confident	0 Å²	0	55.4 Å²	55.4	0%	0	30%	0.3	C	S	.	.	H	α-helix	trans	-59.1	-42.2	173.2	0	0	0	0	0	112.9	W133 S253 F254 L255 F260 M261	W133-G257 VanDerWaalsContact CD1-O 3.22Å; S253-G257 PolarHBondContact O-N 3.2Å; F254-G257 PolarHBondContact O-N 3.39Å; L255-G257 VanDerWaalsContact C-N 3.35Å; L255-G257 PolarHBondContact O-N 3.15Å; G257-F260 PolarHBondContact O-N 3.43Å; G257-M261 PolarHBondContact O-N 3.14Å
258	L	90.6	Very high	86	Confident	48 Å²	48	56.4 Å²	56.4	25%	0.251	30%	0.303	S	S	.	.	H	α-helix	trans	-65.2	-37.4	175.1	-171.9	69.2	0	0	0	112.4	F254 L255 T256 M261 L262	F254-L258 PolarHBondContact O-N 2.71Å; L255-L258 WeakPolarHBondContact O-CB 3.36Å; L255-L258 PolarHBondContact O-N 2.73Å; T256-L258 VanDerWaalsContact C-N 3.34Å; T256-L258 PolarHBondContact O-N 3.01Å; L258-M261 HydrophobicContact CD1-CE 3.58Å; L258-M261 HydrophobicContact CD1-SD 4.23Å; L258-M261 WeakPolarHBondContact O-CB 3.29Å; L258-M261 PolarHBondContact O-N 3.45Å; L258-L262 HydrophobicContact CG-CD1 4.46Å; L258-L262 WeakPolarHBondContact O-CG 3.14Å; L258-L262 PolarHBondContact O-N 3.1Å
259	V	91.3	Very high	84.3	Confident	84 Å²	84	55.1 Å²	55.1	51%	0.509	29%	0.289	S	S	.	.	H	α-helix	trans	-65.5	-43.8	173.8	171.6	0	0	0	0	111	L255 T256 M261 L262 M263	L255-V259 WeakPolarHBondContact O-CG2 3.38Å; L255-V259 PolarHBondContact O-N 3.29Å; T256-V259 PolarHBondContact O-N 3.37Å; V259-M261 VanDerWaalsContact C-N 3.32Å; V259-M261 PolarHBondContact O-N 2.83Å; V259-L262 PolarHBondContact O-N 2.69Å; V259-M263 VanDerWaalsContact O-CB 3.29Å; V259-M263 WeakPolarHBondContact O-CB 3.21Å; V259-M263 PolarHBondContact O-N 3.34Å
260	F	88.5	Confident	82.3	Confident	51 Å²	51	56.2 Å²	56.2	22%	0.224	30%	0.298	C	S	.	.	H	α-helix	trans	-62.6	-37.2	173.9	-78.4	-67.8	0	0	0	112.4	I129 C132 W133 F136 T256 G257 M263 Y264	I129-F260 HydrophobicContact CG2-CD1 4.29Å; I129-F260 WeakPolarHBondContact CG2-O 3.04Å; C132-F260 HydrophobicContact CB-CD1 3.93Å; C132-F260 HydrophobicContact CB-CD2 3.95Å; C132-F260 HydrophobicContact CB-CE1 4.04Å; C132-F260 HydrophobicContact CB-CE2 4.04Å; C132-F260 HydrophobicContact CB-CG 3.92Å; C132-F260 HydrophobicContact CB-CZ 4.1Å; W133-F260 HydrophobicContact CB-CB 3.81Å; F136-F260 AromaticContact CD2-CD2 3.76Å; F136-F260 HydrophobicContact CD2-CD2 3.76Å; F136-F260 AromaticContact CD2-CE2 3.75Å; F136-F260 HydrophobicContact CD2-CE2 3.75Å; F136-F260 HydrophobicContact CE2-CD2 4.05Å; F136-F260 AromaticContact CE2-CE2 3.54Å; F136-F260 HydrophobicContact CE2-CE2 3.54Å; F136-F260 HydrophobicContact CE2-CZ 4.45Å; T256-F260 HydrophobicContact CG2-CD2 3.76Å; T256-F260 HydrophobicContact CG2-CE2 3.49Å; T256-F260 VanDerWaalsContact CG2-CE2 3.49Å; T256-F260 WeakPolarHBondContact O-CD2 3.38Å; T256-F260 PolarHBondContact O-N 2.9Å; G257-F260 PolarHBondContact O-N 3.43Å; F260-M263 HydrophobicContact CD1-CE 3.34Å; F260-M263 HydrophobicContact CE1-CE 3.61Å; F260-M263 HydrophobicContact CG-CE 4.43Å; F260-Y264 WeakPolarHBondContact O-CB 3.41Å; F260-Y264 PolarHBondContact O-N 3.06Å
261	M	85.6	Confident	80	Confident	10 Å²	10	62.2 Å²	62.2	5%	0.049	33%	0.33	C	S	.	.	H	α-helix	trans	-59.1	-55.4	170.8	-175.2	-169	82.8	0	0	111.5	W133 L212 Y216 G257 L258 V259 M263 Y264 Y265	W133-M261 HydrophobicContact CD2-CB 3.78Å; W133-M261 HydrophobicContact CD2-CG 3.98Å; W133-M261 VanDerWaalsContact CE2-CG 3.48Å; W133-M261 HydrophobicContact CE3-CB 4.44Å; W133-M261 HydrophobicContact CE3-CG 4.36Å; W133-M261 HydrophobicContact CG-CB 3.94Å; W133-M261 HydrophobicContact CH2-CG 3.93Å; W133-M261 HydrophobicContact CZ2-CB 4.14Å; W133-M261 HydrophobicContact CZ2-CG 3.48Å; W133-M261 VanDerWaalsContact CZ2-CG 3.48Å; W133-M261 HydrophobicContact CZ2-SD 3.87Å; W133-M261 HydrophobicContact CZ3-CG 4.34Å; L212-M261 HydrophobicContact CD2-CE 4.4Å; L212-M261 HydrophobicContact CD2-SD 3.9Å; L212-M261 HydrophobicContact CG-SD 4.2Å; Y216-M261 HydrophobicContact CD2-SD 3.68Å; Y216-M261 HydrophobicContact CE2-SD 3.62Å; Y216-M261 HydrophobicContact CG-SD 4.44Å; G257-M261 PolarHBondContact O-N 3.14Å; L258-M261 HydrophobicContact CD1-CE 3.58Å; L258-M261 HydrophobicContact CD1-SD 4.23Å; L258-M261 WeakPolarHBondContact O-CB 3.29Å; L258-M261 PolarHBondContact O-N 3.45Å; V259-M261 VanDerWaalsContact C-N 3.32Å; V259-M261 PolarHBondContact O-N 2.83Å; M261-M263 PolarHBondContact O-N 2.82Å; M261-Y264 WeakPolarHBondContact O-CB 3.26Å; M261-Y264 PolarHBondContact O-N 3.26Å; M261-Y264 VanDerWaalsContact O-N 3.08Å; M261-Y265 HydrophobicContact CG-CD2 3.79Å; M261-Y265 HydrophobicContact CG-CE2 3.77Å; M261-Y265 VanDerWaalsContact O-CD2 3.3Å; M261-Y265 WeakPolarHBondContact O-CD2 3.28Å; M261-Y265 PolarHBondContact O-N 3.41Å
262	L	84.5	Confident	77.3	Confident	101 Å²	101	59.4 Å²	59.4	53%	0.529	33%	0.326	S	S	.	.	H	α-helix	trans	-60.1	-38.8	-178.4	-70.5	173.1	0	0	0	110.9	L258 V259 Y265 A266	L258-L262 HydrophobicContact CG-CD1 4.46Å; L258-L262 WeakPolarHBondContact O-CG 3.14Å; L258-L262 PolarHBondContact O-N 3.1Å; V259-L262 PolarHBondContact O-N 2.69Å; L262-Y265 PolarHBondContact O-N 3.32Å; L262-A266 WeakPolarHBondContact O-CB 3.43Å; L262-A266 PolarHBondContact O-N 3.13Å
263	M	83.4	Confident	74.5	Confident	56 Å²	56	62.7 Å²	62.7	28%	0.276	34%	0.343	S	S	.	.	H	α-helix	trans	-62.5	-44.5	173.4	-171.3	170.1	52.7	0	0	112.1	I129 V259 F260 M261 Y265 A266 F267	I129-M263 HydrophobicContact CD1-CE 3.81Å; I129-M263 HydrophobicContact CD1-CG 4.39Å; I129-M263 HydrophobicContact CD1-SD 4.28Å; I129-M263 HydrophobicContact CG1-CE 3.76Å; I129-M263 HydrophobicContact CG2-CE 4Å; V259-M263 VanDerWaalsContact O-CB 3.29Å; V259-M263 WeakPolarHBondContact O-CB 3.21Å; V259-M263 PolarHBondContact O-N 3.34Å; F260-M263 HydrophobicContact CD1-CE 3.34Å; F260-M263 HydrophobicContact CE1-CE 3.61Å; F260-M263 HydrophobicContact CG-CE 4.43Å; M261-M263 PolarHBondContact O-N 2.82Å; M263-Y265 PolarHBondContact O-N 2.8Å; M263-A266 PolarHBondContact O-N 3.49Å; M263-F267 HydrophobicContact CG-CD2 3.5Å; M263-F267 HydrophobicContact CG-CE2 3.69Å; M263-F267 WeakPolarHBondContact O-CD2 3.38Å; M263-F267 PolarHBondContact O-N 2.89Å; M263-F267 HydrophobicContact SD-CE2 4.37Å
264	Y	80.2	Confident	71.7	Confident	25 Å²	25	73.9 Å²	73.9	10%	0.098	38%	0.384	C	S	.	.	H	α-helix	trans	-57.5	-48.7	174.8	-179.9	-98.2	0	0	0	111.7	R113 A126 I129 Q130 W133 F260 M261 F268	R113-Y264 PolarHBondContact NH1-OH 3.09Å; A126-Y264 HydrophobicContact CB-CE2 4.36Å; I129-Y264 HydrophobicContact CG2-CD2 4.48Å; Q130-Y264 HydrophobicContact CB-CD2 4.2Å; Q130-Y264 HydrophobicContact CB-CE2 4.1Å; Q130-Y264 HydrophobicContact CG-CE2 4.4Å; W133-Y264 HydrophobicContact CE3-CD1 4.46Å; W133-Y264 HydrophobicContact CZ3-CD1 4.03Å; W133-Y264 HydrophobicContact CZ3-CE1 4.4Å; F260-Y264 WeakPolarHBondContact O-CB 3.41Å; F260-Y264 PolarHBondContact O-N 3.06Å; M261-Y264 WeakPolarHBondContact O-CB 3.26Å; M261-Y264 PolarHBondContact O-N 3.26Å; M261-Y264 VanDerWaalsContact O-N 3.08Å; Y264-F268 HydrophobicContact CD2-CD2 4.29Å; Y264-F268 WeakPolarHBondContact O-CB 3.26Å; Y264-F268 PolarHBondContact O-N 2.92Å
265	Y	73.6	Confident	68.9	Low	65 Å²	65	83.6 Å²	83.6	26%	0.255	43%	0.426	S	S	.	.	H	α-helix	trans	-73	-31.8	179.6	-75	-78.8	0	0	0	113.5	W133 L212 M261 L262 M263 H269	W133-Y265 AromaticContact CH2-CE2 3.66Å; W133-Y265 HydrophobicContact CH2-CE2 3.66Å; W133-Y265 HydrophobicContact CZ2-CE2 4.45Å; W133-Y265 AromaticContact CZ3-CE2 3.93Å; W133-Y265 HydrophobicContact CZ3-CE2 3.93Å; L212-Y265 HydrophobicContact CD2-CD2 4.28Å; L212-Y265 HydrophobicContact CD2-CE2 3.54Å; M261-Y265 HydrophobicContact CG-CD2 3.79Å; M261-Y265 HydrophobicContact CG-CE2 3.77Å; M261-Y265 VanDerWaalsContact O-CD2 3.3Å; M261-Y265 WeakPolarHBondContact O-CD2 3.28Å; M261-Y265 PolarHBondContact O-N 3.41Å; L262-Y265 PolarHBondContact O-N 3.32Å; M263-Y265 PolarHBondContact O-N 2.8Å; Y265-H269 HydrophobicContact CD1-CB 4.47Å; Y265-H269 WeakPolarHBondContact O-CB 3.29Å; Y265-H269 PolarHBondContact O-N 3.14Å
266	A	71.9	Confident	66	Low	62 Å²	62	81.5 Å²	81.5	51%	0.512	43%	0.431	S	S	.	.	H	α-helix	trans	-70.1	-44.6	177.9	0	0	0	0	0	112.4	L262 M263	L262-A266 WeakPolarHBondContact O-CB 3.43Å; L262-A266 PolarHBondContact O-N 3.13Å; M263-A266 PolarHBondContact O-N 3.49Å
267	F	66.9	Low	62.7	Low	157 Å²	157	90 Å²	90	69%	0.689	46%	0.457	S	S	*	.	H	α-helix	trans	-89.3	-29.8	-176.4	-71.7	-73.3	0	0	0	114.4	M263	M263-F267 HydrophobicContact CG-CD2 3.5Å; M263-F267 HydrophobicContact CG-CE2 3.69Å; M263-F267 WeakPolarHBondContact O-CD2 3.38Å; M263-F267 PolarHBondContact O-N 2.89Å; M263-F267 HydrophobicContact SD-CE2 4.37Å
268	F	60	Low	59.7	Low	52 Å²	52	95.9 Å²	95.9	23%	0.228	50%	0.498	C	S	.	.	H	α-helix	trans	-112.5	-2.7	-173.3	-58.7	-85.7	0	0	0	115	L125 A126 I129 Y264	L125-F268 HydrophobicContact CB-CZ 4.46Å; L125-F268 HydrophobicContact CD2-CZ 4.36Å; L125-F268 HydrophobicContact CG-CZ 4.49Å; A126-F268 HydrophobicContact CB-CD1 3.61Å; A126-F268 HydrophobicContact CB-CD2 3.97Å; A126-F268 HydrophobicContact CB-CE1 3.37Å; A126-F268 HydrophobicContact CB-CE2 3.76Å; A126-F268 HydrophobicContact CB-CG 3.9Å; A126-F268 HydrophobicContact CB-CZ 3.45Å; A126-F268 VanDerWaalsContact CB-CZ 3.45Å; I129-F268 HydrophobicContact CD1-CE2 3.93Å; Y264-F268 HydrophobicContact CD2-CD2 4.29Å; Y264-F268 WeakPolarHBondContact O-CB 3.26Å; Y264-F268 PolarHBondContact O-N 2.92Å
269	H	55.3	Low	56.7	Low	51 Å²	51	99.6 Å²	99.6	24%	0.236	52%	0.523	C	S	.	.			trans	-92	115.7	168.7	-155	-82.3	0	0	0	109.8	Y265 N271 G272	Y265-H269 HydrophobicContact CD1-CB 4.47Å; Y265-H269 WeakPolarHBondContact O-CB 3.29Å; Y265-H269 PolarHBondContact O-N 3.14Å; H269-N271 PolarHBondContact O-N 2.78Å; H269-G272 PolarHBondContact O-N 3.21Å
270	P	49.8	Very low	53.8	Low	97 Å²	97	101.1 Å²	101.1	63%	0.63	54%	0.537	S	S	*	.	T	Hydrogen-bonded Turn	trans	-64.1	-11.3	-173.3	23.8	-33.6	0	0	0	115.1
271	N	43.9	Very low	51	Low	126 Å²	126	104.7 Å²	104.7	67%	0.674	57%	0.567	S	S	*	*	T	Hydrogen-bonded Turn	trans	-109.8	32.2	175.9	-62.8	11	0	0	0	112.3	R209 H269	R209-N271 PolarHBondContact NH2-O 3.06Å; H269-N271 PolarHBondContact O-N 2.78Å
272	G	37.9	Very low	48.3	Very low	29 Å²	29	113.9 Å²	113.9	30%	0.299	61%	0.61	S	S	.	*	S	Bend	trans	-95.9	104.7	161.2	0	0	0	0	0	108.7	H269 R274	H269-G272 PolarHBondContact O-N 3.21Å; G272-R274 PolarHBondContact O-N 3.11Å
273	T	34.4	Very low	45.5	Very low	123 Å²	123	112.5 Å²	112.5	76%	0.755	62%	0.62	S	S	*	*			trans	-3	111.1	172	43.1	0	0	0	0	116.3	F275	T273-F275 PolarHBondContact O-N 2.96Å
274	R	36.2	Very low	42.8	Very low	246 Å²	246	117.9 Å²	117.9	93%	0.928	64%	0.644	S	S	*	*			trans	-51.6	110.4	160.9	-70.3	-176.5	-178.7	-179.1	1.6	108.5	G272 G276	G272-R274 PolarHBondContact O-N 3.11Å; R274-G276 PolarHBondContact O-N 2.82Å
275	F	33.7	Very low	40.3	Very low	214 Å²	214	122.5 Å²	122.5	94%	0.939	67%	0.671	S	S	*	*	S	Bend	trans	-66.5	115.4	170.9	-115.7	-92.3	0	0	0	108.4	T273	T273-F275 PolarHBondContact O-N 2.96Å
276	G	32.8	Very low	38.2	Very low	63 Å²	63	127.4 Å²	127.4	65%	0.649	70%	0.698	S	S	*	*	S	Bend	trans	89.9	111.9	168.8	0	0	0	0	0	116.2	R274	R274-G276 PolarHBondContact O-N 2.82Å
277	R	25.7	Very low	36.1	Very low	231 Å²	231	131.5 Å²	131.5	87%	0.872	71%	0.711	S	S	*	*			trans	71.8	98.2	153.3	-149	168.4	-168.9	154	0.7	117.7	T279	R277-T279 HydrophobicContact CG-CG2 4.42Å; R277-T279 PolarHBondContact O-N 3.25Å
278	S	27.1	Very low	34.4	Very low	122 Å²	122	129.4 Å²	129.4	85%	0.853	71%	0.713	S	S	*	*			trans	-59.7	122.7	151.9	-53.9	0	0	0	0	110.5
279	T	28.9	Very low	32.9	Very low	127 Å²	127	132.8 Å²	132.8	78%	0.779	74%	0.743	S	S	*	*			trans	-131.7	73.6	153.5	48.5	0	0	0	0	107.9	R277	R277-T279 HydrophobicContact CG-CG2 4.42Å; R277-T279 PolarHBondContact O-N 3.25Å
280	S	29.6	Very low	31.7	Very low	115 Å²	115	135.4 Å²	135.4	80%	0.804	77%	0.774	S	S	*	*			trans	-105.1	103	157.9	-174.5	0	0	0	0	106.4
281	C	30.3	Very low	30.6	Very low	126 Å²	126	139.8 Å²	139.8	85%	0.851	79%	0.786	S	S	*	*			trans	169	63.1	160.9	-91.5	0	0	0	0	110.4
282	Q	27.4	Very low	29.7	Very low	203 Å²	203	143.1 Å²	143.1	95%	0.949	80%	0.795	S	S	*	*			trans	169.5	134.5	158.4	-101.2	176.1	26.8	0	0	106
283	G	26.3	Very low	29.2	Very low	72 Å²	72	147.3 Å²	147.3	74%	0.742	82%	0.819	S	S	*	*			cis	-164.4	159.8	-7.6	0	0	0	0	0	107.7
284	H	26.8	Very low	28.8	Very low	169 Å²	169	147.6 Å²	147.6	78%	0.782	82%	0.821	S	S	*	*			trans	-68.6	160.8	171.6	-137.5	-101.5	0	0	0	110
285	D	27.5	Very low	28.2	Very low	123 Å²	123	143.2 Å²	143.2	66%	0.658	82%	0.816	S	S	*	*			trans	73.5	141.9	163.4	-53.5	-33.7	0	0	0	116.8
286	M	29.5	Very low	28.2	Very low	168 Å²	168	139 Å²	139	83%	0.828	81%	0.809	S	S	*	*			cis	-156.3	170.8	2.2	-114.6	-75.3	163.7	0	0	111.7
287	D	28.8	Very low	27.9	Very low	148 Å²	148	140.2 Å²	140.2	79%	0.791	81%	0.808	S	S	*	*			trans	-66	150.8	179.8	-113.8	-34.6	0	0	0	114
288	P	30.7	Very low	28	Very low	113 Å²	113	136.4 Å²	136.4	73%	0.734	81%	0.805	S	S	*	*	S	Bend	trans	-96.9	92.2	179.9	36	-29.9	0	0	0	112.8
289	S	28.2	Very low	27.9	Very low	122 Å²	122	134.6 Å²	134.6	85%	0.853	81%	0.806	S	S	*	*			trans	174.7	96.2	147.3	37.2	0	0	0	0	114.2
290	A	29.8	Very low	27.8	Very low	106 Å²	106	131.8 Å²	131.8	88%	0.876	80%	0.802	S	S	*	*			trans	-145.5	135.2	154.9	0	0	0	0	0	109.2
291	Q	27	Very low	27.7	Very low	190 Å²	190	132 Å²	132	89%	0.888	80%	0.799	S	S	*	*			trans	-90.5	146.9	-170.9	-73.5	176.1	-26.6	0	0	112.6
292	F	25.2	Very low	27.5	Very low	195 Å²	195	133.4 Å²	133.4	86%	0.855	80%	0.798	S	S	*	*			trans	50	112.6	140.1	-129.1	-92.5	0	0	0	119.3
293	S	26.8	Very low	27.5	Very low	117 Å²	117	128.2 Å²	128.2	82%	0.818	78%	0.784	S	S	*	*				-178.1	163.5	117	-79.2	0	0	0	0	112
294	T	26.2	Very low	27.5	Very low	130 Å²	130	132.5 Å²	132.5	80%	0.798	79%	0.789	S	S	*	*			trans	-89.1	157.8	-163.4	45.8	0	0	0	0	115.9
295	L	24.1	Very low	27.5	Very low	154 Å²	154	135.5 Å²	135.5	81%	0.806	79%	0.793	S	S	*	*			trans	-32.3	155.7	153.5	-94.6	160.8	0	0	0	114.6
296	P	33.6	Very low	27.5	Very low	125 Å²	125	134.7 Å²	134.7	81%	0.812	80%	0.797	S	S	*	*				-143.9	-179.1	60.6	39.6	-19.5	0	0	0	119.4
297	S	27.3	Very low	27.3	Very low	89 Å²	89	132.9 Å²	132.9	62%	0.622	79%	0.791	S	S	*	*			trans	-65.6	151.7	-179.5	-166.3	0	0	0	0	115.3
298	D	26.5	Very low	27.3	Very low	151 Å²	151	136.8 Å²	136.8	81%	0.807	80%	0.795	S	S	*	*				150	137.7	120.9	-83	-14.7	0	0	0	115.2
299	G	25.8	Very low	27	Very low	84 Å²	84	134.2 Å²	134.2	87%	0.866	79%	0.789	S	S	*	*			trans	89.3	139	141.1	0	0	0	0	0	120.2
300	G	26.5	Very low	26.9	Very low	68 Å²	68	135 Å²	135	70%	0.701	79%	0.788	S	S	*	*			trans	110.3	65.9	137.1	0	0	0	0	0	120.4
301	T	26.5	Very low	26.7	Very low	120 Å²	120	136.5 Å²	136.5	74%	0.736	79%	0.787	S	S	*	*				41	138.3	125.5	61.9	0	0	0	0	122.9
302	N	27.9	Very low	26.7	Very low	155 Å²	155	130.4 Å²	130.4	83%	0.829	78%	0.775	S	S	*	*			trans	73.9	156.9	148.5	-56.1	-22.1	0	0	0	118.1
303	S	26.1	Very low	26.7	Very low	94 Å²	94	127.3 Å²	127.3	66%	0.657	77%	0.772	S	S	*	*			cis	-169	145	-28.9	-177.9	0	0	0	0	108.8
304	L	27	Very low	26.7	Very low	161 Å²	161	129 Å²	129	84%	0.843	77%	0.771	S	S	*	*			trans	24.4	154.3	152.4	-67.1	167.3	0	0	0	123.8
305	R	27.3	Very low	26.7	Very low	232 Å²	232	128.8 Å²	128.8	88%	0.875	76%	0.761	S	S	*	*			trans	93	114.8	151.5	-140.9	174.3	-160.2	166.7	5.3	114.6
306	S	26.1	Very low	26.9	Very low	106 Å²	106	130.6 Å²	130.6	74%	0.741	76%	0.757	S	S	*	*			cis	82.3	132.6	44.4	-170.1	0	0	0	0	115.3
307	N	26.8	Very low	26.4	Very low	130 Å²	130	130.3 Å²	130.3	70%	0.695	75%	0.749	S	S	*	*			trans	100	91.9	152.1	-140.9	47.4	0	0	0	120.2
308	R	27.9	Very low	26.3	Very low	231 Å²	231	132.1 Å²	132.1	87%	0.872	76%	0.756	S	S	*	*				57	121.3	108.5	-160.5	-175.7	-162	-169.5	4.6	120.6
309	G	25.2	Very low	26.2	Very low	59 Å²	59	128.4 Å²	128.4	61%	0.608	75%	0.754	S	S	*	*			trans	135.3	124.1	131.3	0	0	0	0	0	120.1
310	T	26	Very low	26.1	Very low	138 Å²	138	133.4 Å²	133.4	85%	0.847	75%	0.752	S	S	*	*			trans	61.1	152.7	140.4	41.4	0	0	0	0	119.6
311	T	26.2	Very low	25.9	Very low	137 Å²	137	140.4 Å²	140.4	84%	0.84	76%	0.758	S	S	*	*			cis	-166.3	158.5	19.1	-9.7	0	0	0	0	112.4
312	G	26.1	Very low	25.8	Very low	62 Å²	62	140.7 Å²	140.7	64%	0.639	77%	0.765	S	S	*	*			trans	94.4	146.7	148.8	0	0	0	0	0	119.2
313	T	24.6	Very low	25.7	Very low	131 Å²	131	141.6 Å²	141.6	80%	0.804	77%	0.765	S	S	*	*			cis	169.6	153.9	-25.7	21.3	0	0	0	0	108.3
314	L	27	Very low	25.6	Very low	151 Å²	151	146.9 Å²	146.9	79%	0.791	77%	0.77	S	S	*	*			trans	79.8	148.8	175.4	-48.9	163.4	0	0	0	114.3
315	E	26	Very low	25.4	Very low	126 Å²	126	144.9 Å²	144.9	59%	0.589	76%	0.76	S	S	*	*			cis	-159	155.9	-10.2	-125.8	-178.3	112.5	0	0	114.8
316	R	27.7	Very low	25.2	Very low	193 Å²	193	139.1 Å²	139.1	73%	0.728	76%	0.756	S	S	*	*			trans	37	149.7	135.7	-90.4	-170.6	-174	111.7	0.7	123.4
317	D	24.5	Very low	25.1	Very low	119 Å²	119	139.7 Å²	139.7	64%	0.636	76%	0.758	S	S	*	*			cis	-159.2	153	4.4	-141.8	-17.9	0	0	0	115.3
318	T	24.3	Very low	25.3	Very low	127 Å²	127	141.2 Å²	141.2	78%	0.779	76%	0.764	S	S	*	*			trans	56.6	125.7	148.2	30.2	0	0	0	0	129.1
319	G	25.3	Very low	25.3	Very low	73 Å²	73	135.6 Å²	135.6	75%	0.753	76%	0.758	S	S	*	*				101.7	147	126.7	0	0	0	0	0	119
320	K	23.1	Very low	25.8	Very low	189 Å²	189	138.5 Å²	138.5	82%	0.822	76%	0.764	S	S	*	*			cis	-162.3	147.2	-13.8	-108.1	-163.9	176.2	178.7	0	109.9
321	Y	21.9	Very low	26	Very low	215 Å²	215	141.1 Å²	141.1	84%	0.843	76%	0.764	S	S	*	*			trans	15.4	130.4	157.2	-61.8	-95	0	0	0	122.5
322	S	25.1	Very low	26.3	Very low	125 Å²	125	143.7 Å²	143.7	87%	0.874	77%	0.766	S	S	*	*				-172.6	166.3	97.3	-160.1	0	0	0	0	112.5
323	E	24.8	Very low	26.4	Very low	175 Å²	175	146.4 Å²	146.4	82%	0.818	77%	0.77	S	S	*	*			trans	-102.1	159.5	-166.7	-163.4	174.3	119.4	0	0	112.9
324	R	25.2	Very low	26.6	Very low	204 Å²	204	151.2 Å²	151.2	77%	0.77	77%	0.773	S	S	*	*			trans	118.8	124.1	135.8	-160	165.7	-174.4	166.6	8.1	120.6
325	D	22.2	Very low	26.5	Very low	120 Å²	120	151.6 Å²	151.6	64%	0.642	77%	0.771	S	S	*	*			trans	57.1	130.8	151.3	-60.9	-21.1	0	0	0	124.6
326	S	22.3	Very low	26.8	Very low	111 Å²	111	151.3 Å²	151.3	78%	0.776	78%	0.78	S	S	*	*			trans	91.3	136.2	137.5	-77.5	0	0	0	0	123.2
327	C	24.4	Very low	27	Very low	118 Å²	118	148.1 Å²	148.1	80%	0.797	78%	0.782	S	S	*	*			trans	68.3	98.6	156.6	-62.6	0	0	0	0	118.8	P329	C327-P329 WeakPolarHBondContact O-CD 3.24Å
328	I	31.1	Very low	27.2	Very low	161 Å²	161	148.5 Å²	148.5	83%	0.826	79%	0.79	S	S	*	*	P	Polyproline II helix	trans	-71.9	123.3	158.3	-61.5	169.6	0	0	0	109.2
329	P	28.7	Very low	27.5	Very low	114 Å²	114	147.9 Å²	147.9	74%	0.74	79%	0.791	S	S	*	*	P	Polyproline II helix	trans	-86.4	124.5	161.2	1.5	18.5	0	0	0	109.6	C327	C327-P329 WeakPolarHBondContact O-CD 3.24Å
330	V	36.1	Very low	27.7	Very low	120 Å²	120	150.5 Å²	150.5	73%	0.727	79%	0.793	S	S	*	*	S	Bend	trans	-63.7	153.7	163.5	176.4	0	0	0	0	109.1
331	F	29.9	Very low	28.1	Very low	193 Å²	193	147.9 Å²	147.9	85%	0.846	80%	0.795	S	S	*	*			trans	83.6	96.5	-172.1	-64	-85.6	0	0	0	116
332	Q	31.7	Very low	28.4	Very low	190 Å²	190	142.9 Å²	142.9	89%	0.888	79%	0.792	S	S	*	*			trans	-112.5	95.3	163.7	-157.2	176.3	38.4	0	0	109.5	R334	Q332-R334 PolarHBondContact O-N 2.71Å
333	V	28.9	Very low	28.9	Very low	119 Å²	119	143 Å²	143	72%	0.721	79%	0.792	S	S	*	*			trans	-76	106.3	172.3	176.9	0	0	0	0	108.3	H335	V333-H335 PolarHBondContact O-N 2.78Å
334	R	27.9	Very low	29.1	Very low	232 Å²	232	144.3 Å²	144.3	88%	0.875	79%	0.79	S	S	*	*			trans	-77.9	108.5	176.9	-177.2	-179.6	-84.4	180	-6.2	109.5	Q332	Q332-R334 PolarHBondContact O-N 2.71Å
335	H	25.8	Very low	29.2	Very low	160 Å²	160	138.7 Å²	138.7	74%	0.741	79%	0.787	S	S	*	*	P	Polyproline II helix	trans	-61.1	139.4	169	-76.6	-92.3	0	0	0	110.7	V333	V333-H335 PolarHBondContact O-N 2.78Å
336	P	32.5	Very low	29.7	Very low	120 Å²	120	139 Å²	139	78%	0.779	80%	0.796	S	S	*	*	P	Polyproline II helix	trans	-73.7	130.1	177.4	27.8	-31.1	0	0	0	111.3
337	V	30.6	Very low	30.1	Very low	126 Å²	126	143.4 Å²	143.4	76%	0.764	80%	0.795	S	S	*	*	P	Polyproline II helix	trans	-72.4	141.5	169	177.6	0	0	0	0	108.8	S339	V337-S339 PolarHBondContact O-N 3.07Å
338	P	29.3	Very low	30.5	Very low	126 Å²	126	145.5 Å²	145.5	82%	0.818	80%	0.798	S	S	*	*	P	Polyproline II helix	trans	-68	116.1	179.4	-15.2	29.4	0	0	0	111.1
339	S	30.7	Very low	30.9	Very low	114 Å²	114	145 Å²	145	80%	0.797	80%	0.796	S	S	*	*	P	Polyproline II helix	trans	-86.8	139.4	170	48.6	0	0	0	0	111	V337	V337-S339 PolarHBondContact O-N 3.07Å
340	T	30.1	Very low	31.5	Very low	129 Å²	129	145.6 Å²	145.6	79%	0.791	79%	0.789	S	S	*	*	P	Polyproline II helix	trans	-60.8	146.9	177.9	39.6	0	0	0	0	112.3	S342	T340-S342 PolarHBondContact O-N 2.77Å; T340-S342 VanDerWaalsContact O-N 3.12Å
341	P	31.4	Very low	31.9	Very low	133 Å²	133	142.5 Å²	142.5	86%	0.864	77%	0.771	S	S	*	*			trans	-73.7	108.6	-171.2	28.9	-34.6	0	0	0	111.7
342	S	28.7	Very low	32.9	Very low	111 Å²	111	136 Å²	136	78%	0.776	75%	0.747	S	S	*	*			trans	-88.6	124.6	165.6	-172.4	0	0	0	0	109.8	T340 R344	T340-S342 PolarHBondContact O-N 2.77Å; T340-S342 VanDerWaalsContact O-N 3.12Å; S342-R344 PolarHBondContact O-N 2.99Å
343	S	34.2	Very low	34.1	Very low	126 Å²	126	129.7 Å²	129.7	88%	0.881	72%	0.719	S	S	*	*			trans	-74	81	-179.7	46.3	0	0	0	0	112
344	R	29.7	Very low	35.2	Very low	204 Å²	204	131.7 Å²	131.7	77%	0.77	72%	0.718	S	S	*	*			trans	-129.3	128.2	167.7	-147.3	170	-160.6	153.2	6.2	109.8	S342	S342-R344 PolarHBondContact O-N 2.99Å
345	A	27.3	Very low	36.6	Very low	85 Å²	85	122.3 Å²	122.3	70%	0.702	69%	0.685	S	S	*	*	P	Polyproline II helix	trans	-55	144	-179.2	0	0	0	0	0	111.1	R347	A345-R347 PolarHBondContact O-N 3.47Å; A345-R347 VanDerWaalsContact O-N 3.11Å
346	P	31.5	Very low	37.8	Very low	127 Å²	127	120.6 Å²	120.6	83%	0.825	68%	0.681	S	S	*	*	P	Polyproline II helix	trans	-63	118.9	-177.3	24.3	-30.8	0	0	0	109.2
347	R	31.7	Very low	38.9	Very low	203 Å²	203	117.2 Å²	117.2	77%	0.766	66%	0.656	S	S	*	*	P	Polyproline II helix	trans	-65.1	132.8	161.7	-70.1	177.1	171.5	159.7	-5.5	106.3	A345 D349	A345-R347 PolarHBondContact O-N 3.47Å; A345-R347 VanDerWaalsContact O-N 3.11Å; R347-D349 PolarHBondContact O-N 3.47Å
348	L	32.8	Very low	39.8	Very low	163 Å²	163	113.6 Å²	113.6	85%	0.853	64%	0.636	S	S	*	*			trans	-59.4	114.7	165.4	-81.7	111.3	0	0	0	107.3	E350	L348-E350 PolarHBondContact O-N 2.86Å; L348-E350 VanDerWaalsContact O-N 3.13Å
349	D	39.1	Very low	40.9	Very low	149 Å²	149	109 Å²	109	80%	0.797	60%	0.602	S	S	*	*			trans	-63.5	110.1	162.5	-87.2	-39.5	0	0	0	107.1	R347 T351	R347-D349 PolarHBondContact O-N 3.47Å; D349-T351 PolarHBondContact O-N 3.39Å; D349-T351 VanDerWaalsContact O-N 3.16Å
350	E	41.8	Very low	42	Very low	127 Å²	127	106.2 Å²	106.2	59%	0.593	58%	0.578	S	S	*	*			trans	-58.4	117.6	157.9	-71.4	-171.4	153.1	0	0	106.3	L348 V352 R389	L348-E350 PolarHBondContact O-N 2.86Å; L348-E350 VanDerWaalsContact O-N 3.13Å; E350-V352 HydrophobicContact CB-CG2 4.39Å; E350-V352 PolarHBondContact O-N 3.15Å; E350-R389 IonicContact OE2-NH1 3.95Å
351	T	45.2	Very low	43	Very low	55 Å²	55	105 Å²	105	34%	0.337	56%	0.564	S	S	.	*			trans	-70	81.1	178.7	41.7	0	0	0	0	109.9	D349 I353 P388	D349-T351 PolarHBondContact O-N 3.39Å; D349-T351 VanDerWaalsContact O-N 3.16Å; T351-I353 VanDerWaalsContact C-N 3.35Å; T351-I353 PolarHBondContact O-N 2.94Å; T351-P388 WeakPolarHBondContact O-CB 3.32Å
352	V	50.2	Low	43.8	Very low	57 Å²	57	102 Å²	102	35%	0.345	54%	0.536	S	S	.	.			trans	-73.9	88.6	176.7	-178.5	0	0	0	0	108.8	E350 K354 R389 M391	E350-V352 HydrophobicContact CB-CG2 4.39Å; E350-V352 PolarHBondContact O-N 3.15Å; V352-K354 HydrophobicContact CG1-CG 4.24Å; V352-K354 PolarHBondContact O-N 3.29Å; V352-K354 VanDerWaalsContact O-N 3.11Å; V352-R389 HydrophobicContact CG2-CB 4.44Å; V352-M391 HydrophobicContact CG1-CB 4.1Å; V352-M391 HydrophobicContact CG1-CG 3.77Å; V352-M391 HydrophobicContact CG1-SD 3.85Å
353	I	56.5	Low	44.9	Very low	57 Å²	57	96.9 Å²	96.9	29%	0.292	50%	0.5	S	S	.	.			trans	-73.7	103	173.1	-58.2	176.6	0	0	0	107.7	T351 L355 I378 P388	T351-I353 VanDerWaalsContact C-N 3.35Å; T351-I353 PolarHBondContact O-N 2.94Å; I353-L355 HydrophobicContact CG2-CD1 3.8Å; I353-L355 HydrophobicContact CG2-CG 4.26Å; I353-I378 HydrophobicContact CB-CD1 4.45Å; I353-I378 HydrophobicContact CD1-CB 4.3Å; I353-I378 HydrophobicContact CD1-CD1 3.91Å; I353-I378 HydrophobicContact CD1-CG1 3.77Å; I353-I378 HydrophobicContact CD1-CG2 3.62Å; I353-I378 HydrophobicContact CG2-CD1 4.24Å; I353-P388 HydrophobicContact CD1-CB 4.17Å; I353-P388 HydrophobicContact CD1-CG 4.42Å; I353-P388 HydrophobicContact CG1-CB 4.38Å
354	K	51.9	Low	45.9	Very low	162 Å²	162	91.2 Å²	91.2	70%	0.704	46%	0.461	S	S	*	.	E	Extended strand (participates in β ladder)	trans	-79.6	115.1	172.1	-66.7	-179.4	-179.7	177.7	0	108.7	V352 M391	V352-K354 HydrophobicContact CG1-CG 4.24Å; V352-K354 PolarHBondContact O-N 3.29Å; V352-K354 VanDerWaalsContact O-N 3.11Å; K354-M391 HydrophobicContact CG-CB 4.32Å
355	L	57.4	Low	47	Very low	35 Å²	35	84.2 Å²	84.2	18%	0.183	43%	0.434	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-102.2	122.2	171.9	-72.4	110.3	0	0	0	109.7	I353 L357 I374 I378 L390 M391	I353-L355 HydrophobicContact CG2-CD1 3.8Å; I353-L355 HydrophobicContact CG2-CG 4.26Å; L355-L357 HydrophobicContact CB-CD1 3.95Å; L355-L357 HydrophobicContact CD2-CD1 4.04Å; L355-L357 PolarHBondContact O-N 2.85Å; L355-I374 HydrophobicContact CD1-CG2 3.72Å; L355-I374 HydrophobicContact CD2-CD1 3.98Å; L355-I374 HydrophobicContact CD2-CG1 3.98Å; L355-I374 HydrophobicContact CD2-CG2 3.8Å; L355-I374 HydrophobicContact CG-CG2 4.44Å; L355-I378 HydrophobicContact CD1-CD1 4.36Å; L355-L390 HydrophobicContact CD1-CD2 3.4Å; L355-L390 VanDerWaalsContact CD1-CD2 3.4Å; L355-M391 PolarHBondContact N-O 3.2Å
356	D	51.6	Low	48.3	Very low	124 Å²	124	81.8 Å²	81.8	66%	0.663	41%	0.408	S	S	*	.			trans	-80.5	51.7	179.6	-140.6	-20.5	0	0	0	110.7	K393	D356-K393 WeakPolarHBondContact OD1-CD 3.33Å; D356-K393 WeakPolarHBondContact OD1-CE 3.2Å; D356-K393 IonicContact OD1-NZ 2.71Å; D356-K393 PolarHBondContact OD1-NZ 3.4Å; D356-K393 IonicContact OD2-NZ 2.78Å
357	L	54.8	Low	49.7	Very low	49 Å²	49	77 Å²	77	26%	0.257	37%	0.373	S	S	.	.			trans	-112.4	131	175.2	-78.4	90.6	0	0	0	110.4	L355 R359 L370	L355-L357 HydrophobicContact CB-CD1 3.95Å; L355-L357 HydrophobicContact CD2-CD1 4.04Å; L355-L357 PolarHBondContact O-N 2.85Å; L357-R359 VanDerWaalsContact C-N 3.33Å; L357-R359 PolarHBondContact O-N 3.19Å; L357-L370 HydrophobicContact CD2-CD1 4.04Å; L357-L370 HydrophobicContact CD2-CD2 3.87Å; L357-L370 HydrophobicContact CD2-CG 4.36Å
358	C	50.8	Low	51	Low	49 Å²	49	67.7 Å²	67.7	33%	0.331	34%	0.339	S	S	.	.			trans	-70.6	84.9	176	-63	0	0	0	0	110.7	N360 Q361	C358-N360 PolarHBondContact O-N 3.46Å; C358-N360 VanDerWaalsContact O-N 3.13Å; C358-Q361 HydrophobicContact CB-CB 4.46Å; C358-Q361 WeakPolarHBondContact O-CB 3.19Å; C358-Q361 PolarHBondContact O-N 3.5Å; C358-Q361 VanDerWaalsContact O-N 3.14Å
359	R	51.6	Low	52.2	Low	29 Å²	29	63.1 Å²	63.1	11%	0.109	32%	0.317	C	S	.	.	T	Hydrogen-bonded Turn	trans	-50.5	-39.8	-175.3	175.6	176.2	64.1	-174.7	3.3	114	D118 L357 Q361 R367 Y392 D394	D118-R359 IonicContact OD1-CZ 2.94Å; D118-R359 IonicContact OD1-NH1 2.72Å; D118-R359 PolarHBondContact OD1-NH1 3.34Å; D118-R359 IonicContact OD1-NH2 3.38Å; D118-R359 IonicContact OD2-CZ 2.67Å; D118-R359 IonicContact OD2-NE 2.88Å; D118-R359 IonicContact OD2-NH1 3.66Å; D118-R359 PolarHBondContact OD2-NH1 3.12Å; D118-R359 IonicContact OD2-NH2 3.93Å; L357-R359 VanDerWaalsContact C-N 3.33Å; L357-R359 PolarHBondContact O-N 3.19Å; R359-Q361 VanDerWaalsContact C-N 3.25Å; R359-Q361 PolarHBondContact O-N 2.97Å; R359-R367 WeakPolarHBondContact O-CD 3.46Å; R359-R367 PolarHBondContact O-NE 2.98Å; R359-Y392 HydrophobicContact CB-CD1 3.88Å; R359-Y392 HydrophobicContact CB-CG 3.98Å; R359-Y392 HydrophobicContact CG-CD1 4.36Å; R359-Y392 HydrophobicContact CG-CG 4.31Å; R359-D394 IonicContact CZ-OD1 2.69Å; R359-D394 IonicContact NH2-OD1 2.69Å; R359-D394 PolarHBondContact NH2-OD1 3.2Å; R359-D394 IonicContact NH2-OD2 3.78Å; R359-D394 PolarHBondContact NH2-OD2 2.85Å
360	N	53.2	Low	53.3	Low	56 Å²	56	58 Å²	58	30%	0.299	29%	0.29	S	S	.	.	T	Hydrogen-bonded Turn	trans	-76.7	-11	-172.4	-65.1	-40.7	0	0	0	113.9	C358 R367 D395	C358-N360 PolarHBondContact O-N 3.46Å; C358-N360 VanDerWaalsContact O-N 3.13Å; N360-R367 PolarHBondContact O-NH2 3.36Å; N360-D395 WeakPolarHBondContact CB-OD2 3.49Å; N360-D395 PolarHBondContact ND2-OD2 3.19Å
361	Q	51.2	Low	54.3	Low	104 Å²	104	52.6 Å²	52.6	49%	0.486	27%	0.265	S	S	.	.	T	Hydrogen-bonded Turn	trans	-65.2	-67.2	176.7	-120.4	177.5	-43.7	0	0	109.2	F178 C358 R359	F178-Q361 HydrophobicContact CE1-CB 3.55Å; F178-Q361 HydrophobicContact CE1-CG 3.58Å; F178-Q361 WeakPolarHBondContact CE1-O 3.4Å; F178-Q361 VanDerWaalsContact CZ-C 3.48Å; F178-Q361 HydrophobicContact CZ-CB 4.03Å; F178-Q361 HydrophobicContact CZ-CG 3.71Å; F178-Q361 WeakPolarHBondContact CZ-O 3.39Å; C358-Q361 HydrophobicContact CB-CB 4.46Å; C358-Q361 WeakPolarHBondContact O-CB 3.19Å; C358-Q361 PolarHBondContact O-N 3.5Å; C358-Q361 VanDerWaalsContact O-N 3.14Å; R359-Q361 VanDerWaalsContact C-N 3.25Å; R359-Q361 PolarHBondContact O-N 2.97Å
362	Y	48.7	Very low	55.2	Low	71 Å²	71	52.1 Å²	52.1	28%	0.278	26%	0.257	S	S	.	.	S	Bend	trans	-56.1	149.8	-170	-55.4	-80.2	0	0	0	115.4	E366 R367 L370	Y362-E366 WeakPolarHBondContact CD1-OE2 3.46Å; Y362-R367 PolarHBondContact O-NE 2.66Å; Y362-R367 PolarHBondContact O-NH2 3.13Å; Y362-R367 VanDerWaalsContact O-NH2 3.1Å; Y362-L370 HydrophobicContact CD2-CD2 3.83Å; Y362-L370 HydrophobicContact CE2-CD2 3.88Å; Y362-L370 HydrophobicContact CG-CD2 4.32Å
363	P	51.4	Low	55.8	Low	3 Å²	3	51.9 Å²	51.9	2%	0.019	26%	0.258	C	S	.	.			trans	-59	158.5	167.8	22.4	-30	0	0	0	113.1	V203 K204 W365 E366 R367	V203-P363 HydrophobicContact CG1-CB 3.94Å; K204-P363 HydrophobicContact CG-CB 3.77Å; P363-W365 PolarHBondContact O-N 3.28Å; P363-E366 VanDerWaalsContact CD-OE2 3.22Å; P363-E366 WeakPolarHBondContact CD-OE2 3.33Å; P363-E366 HydrophobicContact CG-CB 3.79Å; P363-E366 HydrophobicContact CG-CG 3.75Å; P363-E366 PolarHBondContact O-N 2.9Å; P363-R367 WeakPolarHBondContact O-CG 3.39Å; P363-R367 PolarHBondContact O-N 3.04Å
364	A	56.2	Low	56.2	Low	7 Å²	7	50 Å²	50	6%	0.058	25%	0.248	C	C	.	.	H	α-helix	trans	-60.1	-33.9	-172.9	0	0	0	0	0	112.8	L112 V203 E205 H368	L112-A364 HydrophobicContact CD1-CB 4.31Å; L112-A364 HydrophobicContact CD2-CB 4.41Å; V203-A364 WeakPolarHBondContact O-CB 3.37Å; V203-A364 PolarHBondContact O-N 3.47Å; E205-A364 HydrophobicContact CB-CB 4.5Å; E205-A364 HydrophobicContact CG-CB 4.03Å; A364-H368 VanDerWaalsContact O-CB 3.25Å; A364-H368 WeakPolarHBondContact O-CB 3.46Å; A364-H368 PolarHBondContact O-N 3.12Å
365	W	52.4	Low	56.8	Low	57 Å²	57	43.9 Å²	43.9	22%	0.216	22%	0.221	C	C	.	.	H	α-helix	trans	-74.4	-36.1	175.7	76	-94.7	0	0	0	112.8	F188 P363 H368 V369	F188-W365 AromaticContact CE1-NE1 3.81Å; F188-W365 AromaticContact CZ-CD1 3.81Å; F188-W365 AromaticContact CZ-NE1 3.74Å; P363-W365 PolarHBondContact O-N 3.28Å; W365-H368 WeakPolarHBondContact O-CB 3.45Å; W365-H368 PolarHBondContact O-N 3.16Å; W365-V369 HydrophobicContact CE3-CG2 4.12Å; W365-V369 HydrophobicContact CZ3-CG2 4.4Å; W365-V369 WeakPolarHBondContact O-CG2 3.49Å; W365-V369 PolarHBondContact O-N 2.88Å
366	E	55.1	Low	57.1	Low	34 Å²	34	48 Å²	48	16%	0.159	24%	0.237	C	C	.	.	H	α-helix	trans	-72.2	-39.7	172.9	-77.4	-169.7	154.6	0	0	111.5	C179 Y362 P363 H368 V369 L370	C179-E366 PolarHBondContact SG-OE1 3.13Å; Y362-E366 WeakPolarHBondContact CD1-OE2 3.46Å; P363-E366 VanDerWaalsContact CD-OE2 3.22Å; P363-E366 WeakPolarHBondContact CD-OE2 3.33Å; P363-E366 HydrophobicContact CG-CB 3.79Å; P363-E366 HydrophobicContact CG-CG 3.75Å; P363-E366 PolarHBondContact O-N 2.9Å; E366-H368 PolarHBondContact O-N 3.12Å; E366-V369 PolarHBondContact O-N 3.08Å; E366-V369 VanDerWaalsContact O-N 3.15Å; E366-L370 WeakPolarHBondContact O-CB 3.49Å; E366-L370 PolarHBondContact O-N 3.16Å
367	R	59.9	Low	57.6	Low	25 Å²	25	46.2 Å²	46.2	9%	0.094	23%	0.23	C	C	.	.	H	α-helix	trans	-53.7	-43.5	169.2	-69.4	179.5	-162.1	163.7	6.6	110.5	E205 R359 N360 Y362 P363 D371	E205-R367 PolarHBondContact O-NH1 3.48Å; E205-R367 PolarHBondContact O-NH2 3.23Å; R359-R367 WeakPolarHBondContact O-CD 3.46Å; R359-R367 PolarHBondContact O-NE 2.98Å; N360-R367 PolarHBondContact O-NH2 3.36Å; Y362-R367 PolarHBondContact O-NE 2.66Å; Y362-R367 PolarHBondContact O-NH2 3.13Å; Y362-R367 VanDerWaalsContact O-NH2 3.1Å; P363-R367 WeakPolarHBondContact O-CG 3.39Å; P363-R367 PolarHBondContact O-N 3.04Å; R367-D371 WeakPolarHBondContact O-CB 3.37Å; R367-D371 PolarHBondContact O-N 2.63Å
368	H	59.3	Low	57.8	Low	8 Å²	8	44.6 Å²	44.6	4%	0.037	22%	0.222	C	C	.	.	H	α-helix	trans	-64.1	-45.6	175.6	163	-92.6	0	0	0	112.9	Y52 D56 A364 W365 E366 R372	Y52-H368 WeakPolarHBondContact CA-NE2 3.3Å; Y52-H368 VanDerWaalsContact CB-NE2 3.33Å; Y52-H368 WeakPolarHBondContact CB-NE2 3.46Å; Y52-H368 AromaticContact CD1-CD2 3.24Å; Y52-H368 WeakPolarHBondContact CD1-CD2 3.46Å; Y52-H368 AromaticContact CD1-NE2 3.24Å; Y52-H368 WeakPolarHBondContact CD1-NE2 3.36Å; Y52-H368 AromaticContact CE1-CD2 3.83Å; Y52-H368 AromaticContact CG-NE2 3.63Å; Y52-H368 PolarHBondContact O-NE2 2.92Å; D56-H368 IonicContact OD1-CE1 2.66Å; D56-H368 PolarHBondContact OD1-CE1 3.49Å; D56-H368 IonicContact OD1-ND1 3.58Å; A364-H368 VanDerWaalsContact O-CB 3.25Å; A364-H368 WeakPolarHBondContact O-CB 3.46Å; A364-H368 PolarHBondContact O-N 3.12Å; W365-H368 WeakPolarHBondContact O-CB 3.45Å; W365-H368 PolarHBondContact O-N 3.16Å; E366-H368 PolarHBondContact O-N 3.12Å; H368-R372 WeakPolarHBondContact O-CB 3.29Å; H368-R372 PolarHBondContact O-N 3.45Å
369	V	58.6	Low	58.1	Low	67 Å²	67	46.3 Å²	46.3	41%	0.406	23%	0.227	S	C	.	.	H	α-helix	trans	-66.4	-39.6	176.7	169.3	0	0	0	0	111.9	W365 E366 S373	W365-V369 HydrophobicContact CE3-CG2 4.12Å; W365-V369 HydrophobicContact CZ3-CG2 4.4Å; W365-V369 WeakPolarHBondContact O-CG2 3.49Å; W365-V369 PolarHBondContact O-N 2.88Å; E366-V369 PolarHBondContact O-N 3.08Å; E366-V369 VanDerWaalsContact O-N 3.15Å; V369-S373 WeakPolarHBondContact O-CB 3.24Å; V369-S373 PolarHBondContact O-N 2.89Å
370	L	62.2	Low	58.5	Low	43 Å²	43	48.9 Å²	48.9	23%	0.225	26%	0.255	C	S	.	.	H	α-helix	trans	-69.7	-46.7	178.3	-177.7	63.7	0	0	0	111.1	L357 Y362 E366 R372 S373 I374	L357-L370 HydrophobicContact CD2-CD1 4.04Å; L357-L370 HydrophobicContact CD2-CD2 3.87Å; L357-L370 HydrophobicContact CD2-CG 4.36Å; Y362-L370 HydrophobicContact CD2-CD2 3.83Å; Y362-L370 HydrophobicContact CE2-CD2 3.88Å; Y362-L370 HydrophobicContact CG-CD2 4.32Å; E366-L370 WeakPolarHBondContact O-CB 3.49Å; E366-L370 PolarHBondContact O-N 3.16Å; L370-R372 VanDerWaalsContact C-N 3.33Å; L370-R372 PolarHBondContact O-N 3.4Å; L370-S373 PolarHBondContact O-N 3.11Å; L370-S373 VanDerWaalsContact O-N 3.14Å; L370-S373 PolarHBondContact O-OG 3.44Å; L370-I374 HydrophobicContact CD1-CD1 4.01Å; L370-I374 HydrophobicContact CD1-CG1 4.43Å; L370-I374 HydrophobicContact CG-CD1 3.78Å; L370-I374 VanDerWaalsContact O-CB 3.3Å; L370-I374 WeakPolarHBondContact O-CB 3.26Å; L370-I374 WeakPolarHBondContact O-CD1 3.5Å; L370-I374 WeakPolarHBondContact O-CG1 3.35Å; L370-I374 PolarHBondContact O-N 3.17Å
371	D	63	Low	58.5	Low	12 Å²	12	53.8 Å²	53.8	6%	0.064	28%	0.278	C	S	.	.	H	α-helix	trans	-62.2	-41.4	173.2	-173.5	35.9	0	0	0	110.9	Y52 R367 S373 R375 L390 Y392	Y52-D371 PolarHBondContact OH-OD2 3.24Å; R367-D371 WeakPolarHBondContact O-CB 3.37Å; R367-D371 PolarHBondContact O-N 2.63Å; D371-S373 VanDerWaalsContact C-N 3.34Å; D371-S373 PolarHBondContact O-N 2.85Å; D371-R375 VanDerWaalsContact O-CB 3.28Å; D371-R375 WeakPolarHBondContact O-CB 3.27Å; D371-R375 VanDerWaalsContact O-CG 3.26Å; D371-R375 WeakPolarHBondContact O-CG 3.42Å; D371-R375 PolarHBondContact O-N 3.05Å; D371-R375 IonicContact OD1-CZ 3.53Å; D371-R375 IonicContact OD1-NE 2.9Å; D371-R375 PolarHBondContact OD1-NE 3.22Å; D371-R375 IonicContact OD1-NH2 3.91Å; D371-R375 PolarHBondContact OD1-NH2 3.2Å; D371-R375 IonicContact OD2-CZ 3.42Å; D371-R375 IonicContact OD2-NE 2.65Å; D371-R375 PolarHBondContact OD2-NE 3.02Å; D371-R375 VanDerWaalsContact OD2-NE 3.07Å; D371-R375 IonicContact OD2-NH2 2.73Å; D371-R375 PolarHBondContact OD2-NH2 2.76Å; D371-L390 WeakPolarHBondContact OD1-CD1 3.14Å; D371-Y392 PolarHBondContact OD1-OH 3.07Å; D371-Y392 VanDerWaalsContact OD1-OH 3.04Å
372	R	62.6	Low	58.5	Low	46 Å²	46	51.4 Å²	51.4	17%	0.174	27%	0.268	C	S	.	.	H	α-helix	trans	-63.2	-34.7	171.7	-178.5	-179.4	-178.5	-167.5	3.6	112.8	Y52 E53 D56 H368 L370 K376	Y52-R372 HydrophobicContact CD2-CB 4.03Å; Y52-R372 HydrophobicContact CD2-CG 3.93Å; Y52-R372 HydrophobicContact CE2-CB 3.99Å; Y52-R372 HydrophobicContact CE2-CG 4.26Å; Y52-R372 HydrophobicContact CG-CB 4.5Å; E53-R372 IonicContact OE1-CZ 3.84Å; E53-R372 IonicContact OE1-NH2 3.21Å; E53-R372 PolarHBondContact OE1-NH2 3.35Å; D56-R372 IonicContact OD2-CZ 3.6Å; D56-R372 IonicContact OD2-NH1 3.72Å; D56-R372 PolarHBondContact OD2-NH1 2.9Å; D56-R372 IonicContact OD2-NH2 3.77Å; H368-R372 WeakPolarHBondContact O-CB 3.29Å; H368-R372 PolarHBondContact O-N 3.45Å; L370-R372 VanDerWaalsContact C-N 3.33Å; L370-R372 PolarHBondContact O-N 3.4Å; R372-K376 HydrophobicContact CG-CD 4.49Å; R372-K376 WeakPolarHBondContact O-CB 3.38Å; R372-K376 WeakPolarHBondContact O-CD 3.16Å; R372-K376 WeakPolarHBondContact O-CG 3.48Å; R372-K376 PolarHBondContact O-N 3.16Å; R372-K376 VanDerWaalsContact O-N 3.15Å
373	S	63	Low	58.5	Low	52 Å²	52	53.9 Å²	53.9	36%	0.364	30%	0.295	S	S	.	.	H	α-helix	trans	-76.6	-45.6	177.8	74.8	0	0	0	0	111.3	V369 L370 D371 K376 V377	V369-S373 WeakPolarHBondContact O-CB 3.24Å; V369-S373 PolarHBondContact O-N 2.89Å; L370-S373 PolarHBondContact O-N 3.11Å; L370-S373 VanDerWaalsContact O-N 3.14Å; L370-S373 PolarHBondContact O-OG 3.44Å; D371-S373 VanDerWaalsContact C-N 3.34Å; D371-S373 PolarHBondContact O-N 2.85Å; S373-K376 WeakPolarHBondContact O-CB 3.42Å; S373-K376 PolarHBondContact O-N 3.42Å; S373-V377 WeakPolarHBondContact O-CG2 3.14Å; S373-V377 PolarHBondContact O-N 2.96Å
374	I	65.3	Low	58.3	Low	16 Å²	16	55.4 Å²	55.4	8%	0.082	31%	0.306	C	S	.	.	H	α-helix	trans	-56.5	-51.4	173.5	-71.1	163.8	0	0	0	110.2	L355 L370 K376 V377 I378 L390	L355-I374 HydrophobicContact CD1-CG2 3.72Å; L355-I374 HydrophobicContact CD2-CD1 3.98Å; L355-I374 HydrophobicContact CD2-CG1 3.98Å; L355-I374 HydrophobicContact CD2-CG2 3.8Å; L355-I374 HydrophobicContact CG-CG2 4.44Å; L370-I374 HydrophobicContact CD1-CD1 4.01Å; L370-I374 HydrophobicContact CD1-CG1 4.43Å; L370-I374 HydrophobicContact CG-CD1 3.78Å; L370-I374 VanDerWaalsContact O-CB 3.3Å; L370-I374 WeakPolarHBondContact O-CB 3.26Å; L370-I374 WeakPolarHBondContact O-CD1 3.5Å; L370-I374 WeakPolarHBondContact O-CG1 3.35Å; L370-I374 PolarHBondContact O-N 3.17Å; I374-K376 VanDerWaalsContact C-N 3.34Å; I374-K376 PolarHBondContact O-N 3.27Å; I374-V377 PolarHBondContact O-N 3.5Å; I374-V377 VanDerWaalsContact O-N 3.15Å; I374-I378 HydrophobicContact CG2-CD1 3.53Å; I374-I378 HydrophobicContact CG2-CG1 4.35Å; I374-I378 WeakPolarHBondContact O-CB 3.02Å; I374-I378 VanDerWaalsContact O-CG1 3.26Å; I374-I378 WeakPolarHBondContact O-CG1 3.26Å; I374-I378 PolarHBondContact O-N 2.89Å; I374-L390 HydrophobicContact CG2-CD2 3.97Å
375	R	64.8	Low	57.8	Low	34 Å²	34	62 Å²	62	13%	0.128	34%	0.337	C	S	.	.	H	α-helix	trans	-63.6	-36.1	177.5	-69.8	-178.1	-156.5	-132.8	12.5	112.7	Y52 D117 D371 L379 L390	Y52-R375 VanDerWaalsContact OH-CD 3.29Å; Y52-R375 WeakPolarHBondContact OH-CD 3.12Å; Y52-R375 PolarHBondContact OH-NE 3.38Å; Y52-R375 VanDerWaalsContact OH-NE 3.1Å; D117-R375 IonicContact OD2-CZ 3.31Å; D117-R375 IonicContact OD2-NH1 3.06Å; D117-R375 PolarHBondContact OD2-NH1 2.82Å; D117-R375 IonicContact OD2-NH2 3.8Å; D117-R375 PolarHBondContact OD2-NH2 3.14Å; D371-R375 VanDerWaalsContact O-CB 3.28Å; D371-R375 WeakPolarHBondContact O-CB 3.27Å; D371-R375 VanDerWaalsContact O-CG 3.26Å; D371-R375 WeakPolarHBondContact O-CG 3.42Å; D371-R375 PolarHBondContact O-N 3.05Å; D371-R375 IonicContact OD1-CZ 3.53Å; D371-R375 IonicContact OD1-NE 2.9Å; D371-R375 PolarHBondContact OD1-NE 3.22Å; D371-R375 IonicContact OD1-NH2 3.91Å; D371-R375 PolarHBondContact OD1-NH2 3.2Å; D371-R375 IonicContact OD2-CZ 3.42Å; D371-R375 IonicContact OD2-NE 2.65Å; D371-R375 PolarHBondContact OD2-NE 3.02Å; D371-R375 VanDerWaalsContact OD2-NE 3.07Å; D371-R375 IonicContact OD2-NH2 2.73Å; D371-R375 PolarHBondContact OD2-NH2 2.76Å; R375-L379 VanDerWaalsContact O-CB 3.24Å; R375-L379 WeakPolarHBondContact O-CB 3.24Å; R375-L379 WeakPolarHBondContact O-CD1 3.18Å; R375-L379 WeakPolarHBondContact O-CG 3.41Å; R375-L379 PolarHBondContact O-N 3.41Å; R375-L390 HydrophobicContact CG-CD1 3.93Å
376	K	63.3	Low	57.4	Low	123 Å²	123	63.1 Å²	63.1	54%	0.535	35%	0.35	S	S	.	.	H	α-helix	trans	-63.4	-41.9	172.1	-79.7	168.8	-177	174.3	0	112.3	R372 S373 I374 A380	R372-K376 HydrophobicContact CG-CD 4.49Å; R372-K376 WeakPolarHBondContact O-CB 3.38Å; R372-K376 WeakPolarHBondContact O-CD 3.16Å; R372-K376 WeakPolarHBondContact O-CG 3.48Å; R372-K376 PolarHBondContact O-N 3.16Å; R372-K376 VanDerWaalsContact O-N 3.15Å; S373-K376 WeakPolarHBondContact O-CB 3.42Å; S373-K376 PolarHBondContact O-N 3.42Å; I374-K376 VanDerWaalsContact C-N 3.34Å; I374-K376 PolarHBondContact O-N 3.27Å; K376-A380 WeakPolarHBondContact O-CB 3.3Å; K376-A380 PolarHBondContact O-N 3.4Å; K376-A380 VanDerWaalsContact O-N 3.13Å
377	V	61.7	Low	57.1	Low	85 Å²	85	65 Å²	65	52%	0.515	37%	0.365	S	S	.	.	H	α-helix	trans	-67.2	-44.2	177.8	169.8	0	0	0	0	110.5	S373 I374 A380 M381	S373-V377 WeakPolarHBondContact O-CG2 3.14Å; S373-V377 PolarHBondContact O-N 2.96Å; I374-V377 PolarHBondContact O-N 3.5Å; I374-V377 VanDerWaalsContact O-N 3.15Å; V377-A380 CarbonylContact O-C 3.57Å; V377-A380 WeakPolarHBondContact O-CB 3.47Å; V377-A380 PolarHBondContact O-N 2.98Å; V377-A380 VanDerWaalsContact O-N 3.08Å; V377-M381 HydrophobicContact CG1-CG 4.43Å; V377-M381 HydrophobicContact CG1-SD 4.11Å; V377-M381 WeakPolarHBondContact O-CG 3.32Å; V377-M381 PolarHBondContact O-N 2.9Å
378	I	60	Low	56.6	Low	15 Å²	15	64.9 Å²	64.9	8%	0.077	37%	0.368	C	S	.	.	H	α-helix	trans	-61.6	-47.5	176.5	-70	169.2	0	0	0	111.2	I353 L355 I374 A380 M381 D382 P388 L390	I353-I378 HydrophobicContact CB-CD1 4.45Å; I353-I378 HydrophobicContact CD1-CB 4.3Å; I353-I378 HydrophobicContact CD1-CD1 3.91Å; I353-I378 HydrophobicContact CD1-CG1 3.77Å; I353-I378 HydrophobicContact CD1-CG2 3.62Å; I353-I378 HydrophobicContact CG2-CD1 4.24Å; L355-I378 HydrophobicContact CD1-CD1 4.36Å; I374-I378 HydrophobicContact CG2-CD1 3.53Å; I374-I378 HydrophobicContact CG2-CG1 4.35Å; I374-I378 WeakPolarHBondContact O-CB 3.02Å; I374-I378 VanDerWaalsContact O-CG1 3.26Å; I374-I378 WeakPolarHBondContact O-CG1 3.26Å; I374-I378 PolarHBondContact O-N 2.89Å; I378-A380 PolarHBondContact O-N 3.13Å; I378-A380 VanDerWaalsContact O-N 3.16Å; I378-M381 PolarHBondContact O-N 3.28Å; I378-M381 VanDerWaalsContact O-N 3.12Å; I378-D382 PolarHBondContact O-N 2.93Å; I378-P388 HydrophobicContact CG2-CB 4.44Å; I378-P388 HydrophobicContact CG2-CG 3.41Å; I378-P388 VanDerWaalsContact CG2-CG 3.41Å; I378-L390 HydrophobicContact CD1-CD2 3.63Å
379	L	57.7	Low	56	Low	85 Å²	85	72.3 Å²	72.3	45%	0.445	40%	0.395	S	S	.	.	H	α-helix	trans	-63.9	-16.1	174.7	-71.4	169.3	0	0	0	113.8	Q45 R375	Q45-L379 HydrophobicContact CG-CD1 4.48Å; Q45-L379 HydrophobicContact CG-CD2 4.22Å; R375-L379 VanDerWaalsContact O-CB 3.24Å; R375-L379 WeakPolarHBondContact O-CB 3.24Å; R375-L379 WeakPolarHBondContact O-CD1 3.18Å; R375-L379 WeakPolarHBondContact O-CG 3.41Å; R375-L379 PolarHBondContact O-N 3.41Å
380	A	58.4	Low	55.8	Low	84 Å²	84	70.6 Å²	70.6	69%	0.694	38%	0.384	S	S	*	.	H	α-helix	trans	-95.3	-23.7	174.4	0	0	0	0	0	113.1	K376 V377 I378	K376-A380 WeakPolarHBondContact O-CB 3.3Å; K376-A380 PolarHBondContact O-N 3.4Å; K376-A380 VanDerWaalsContact O-N 3.13Å; V377-A380 CarbonylContact O-C 3.57Å; V377-A380 WeakPolarHBondContact O-CB 3.47Å; V377-A380 PolarHBondContact O-N 2.98Å; V377-A380 VanDerWaalsContact O-N 3.08Å; I378-A380 PolarHBondContact O-N 3.13Å; I378-A380 VanDerWaalsContact O-N 3.16Å
381	M	54.8	Low	55.1	Low	159 Å²	159	73.5 Å²	73.5	78%	0.783	40%	0.398	S	S	*	.	H	α-helix	trans	-89.7	-32.7	176.8	-75.3	-173.2	67.4	0	0	113.2	V377 I378	V377-M381 HydrophobicContact CG1-CG 4.43Å; V377-M381 HydrophobicContact CG1-SD 4.11Å; V377-M381 WeakPolarHBondContact O-CG 3.32Å; V377-M381 PolarHBondContact O-N 2.9Å; I378-M381 PolarHBondContact O-N 3.28Å; I378-M381 VanDerWaalsContact O-N 3.12Å
382	D	50	Low	54.6	Low	53 Å²	53	74.7 Å²	74.7	28%	0.283	40%	0.402	S	S	.	.			trans	-124.9	111.7	-170.7	-164.6	18.9	0	0	0	110.4	I378 S384	I378-D382 PolarHBondContact O-N 2.93Å; D382-S384 PolarHBondContact O-N 3.3Å; D382-S384 VanDerWaalsContact OD2-CB 3.27Å; D382-S384 WeakPolarHBondContact OD2-CB 3.23Å; D382-S384 PolarHBondContact OD2-OG 3.49Å
383	C	49.9	Very low	53.9	Low	123 Å²	123	77.1 Å²	77.1	83%	0.831	41%	0.413	S	S	*	.			trans	-76.7	29.9	176	-64.2	0	0	0	0	112.6
384	S	45.3	Very low	53	Low	35 Å²	35	78.4 Å²	78.4	25%	0.245	42%	0.416	C	S	.	.			trans	-80.1	143	-171.9	56.9	0	0	0	0	112.4	D382 T386	D382-S384 PolarHBondContact O-N 3.3Å; D382-S384 VanDerWaalsContact OD2-CB 3.27Å; D382-S384 WeakPolarHBondContact OD2-CB 3.23Å; D382-S384 PolarHBondContact OD2-OG 3.49Å; S384-T386 VanDerWaalsContact C-N 3.29Å; S384-T386 PolarHBondContact O-N 2.87Å
385	M	47.4	Very low	52.1	Low	146 Å²	146	80.7 Å²	80.7	72%	0.719	43%	0.429	S	S	*	.	S	Bend	trans	-87.3	5.6	-170.1	-69.4	-70.5	149.4	0	0	113.9
386	T	44.2	Very low	51.1	Low	80 Å²	80	82.5 Å²	82.5	49%	0.491	45%	0.45	S	S	.	.	S	Bend	trans	-132.9	143.9	-176.2	42.4	0	0	0	0	109.7	S384 P388	S384-T386 VanDerWaalsContact C-N 3.29Å; S384-T386 PolarHBondContact O-N 2.87Å; T386-P388 VanDerWaalsContact O-CD 3.26Å; T386-P388 WeakPolarHBondContact O-CD 3.3Å
387	P	47.3	Very low	49.8	Very low	73 Å²	73	83.3 Å²	83.3	47%	0.474	46%	0.458	S	S	.	.			trans	-62.5	119.6	177.3	24.1	-32.2	0	0	0	110.9	W44 R389	W44-P387 HydrophobicContact CZ2-CB 3.72Å; W44-P387 HydrophobicContact CZ2-CG 4.16Å; P387-R389 PolarHBondContact O-N 3.48Å
388	P	50.1	Low	48.7	Very low	23 Å²	23	82.1 Å²	82.1	15%	0.149	45%	0.451	C	S	.	.			trans	-66.3	132.2	173.5	23.7	-28.8	0	0	0	109.3	T351 I353 I378 T386 L390	T351-P388 WeakPolarHBondContact O-CB 3.32Å; I353-P388 HydrophobicContact CD1-CB 4.17Å; I353-P388 HydrophobicContact CD1-CG 4.42Å; I353-P388 HydrophobicContact CG1-CB 4.38Å; I378-P388 HydrophobicContact CG2-CB 4.44Å; I378-P388 HydrophobicContact CG2-CG 3.41Å; I378-P388 VanDerWaalsContact CG2-CG 3.41Å; T386-P388 VanDerWaalsContact O-CD 3.26Å; T386-P388 WeakPolarHBondContact O-CD 3.3Å; P388-L390 PolarHBondContact O-N 2.81Å; P388-L390 VanDerWaalsContact O-N 3.14Å
389	R	47.5	Very low	47.4	Very low	164 Å²	164	88 Å²	88	62%	0.619	48%	0.478	S	S	*	.			trans	-80.8	101.1	-173.3	-164.5	173.9	-177.4	179.7	-1.4	109.5	E350 V352 P387 M391	E350-R389 IonicContact OE2-NH1 3.95Å; V352-R389 HydrophobicContact CG2-CB 4.44Å; P387-R389 PolarHBondContact O-N 3.48Å; R389-M391 PolarHBondContact O-N 2.92Å; R389-M391 VanDerWaalsContact O-N 3.15Å
390	L	54.1	Low	46.4	Very low	32 Å²	32	89.8 Å²	89.8	17%	0.168	48%	0.484	C	S	.	.			trans	-64.9	109.9	179.1	-69.3	165.1	0	0	0	110.5	L355 D371 I374 R375 I378 P388 Y392	L355-L390 HydrophobicContact CD1-CD2 3.4Å; L355-L390 VanDerWaalsContact CD1-CD2 3.4Å; D371-L390 WeakPolarHBondContact OD1-CD1 3.14Å; I374-L390 HydrophobicContact CG2-CD2 3.97Å; R375-L390 HydrophobicContact CG-CD1 3.93Å; I378-L390 HydrophobicContact CD1-CD2 3.63Å; P388-L390 PolarHBondContact O-N 2.81Å; P388-L390 VanDerWaalsContact O-N 3.14Å; L390-Y392 HydrophobicContact CB-CD2 4.47Å; L390-Y392 HydrophobicContact CB-CE2 3.9Å
391	M	46.9	Very low	45.1	Very low	103 Å²	103	93.7 Å²	93.7	51%	0.507	48%	0.481	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-99.5	107.6	168	-78.3	-165.9	73.6	0	0	109.5	V352 K354 L355 R389	V352-M391 HydrophobicContact CG1-CB 4.1Å; V352-M391 HydrophobicContact CG1-CG 3.77Å; V352-M391 HydrophobicContact CG1-SD 3.85Å; K354-M391 HydrophobicContact CG-CB 4.32Å; L355-M391 PolarHBondContact N-O 3.2Å; R389-M391 PolarHBondContact O-N 2.92Å; R389-M391 VanDerWaalsContact O-N 3.15Å
392	Y	53.2	Low	44	Very low	38 Å²	38	90.5 Å²	90.5	15%	0.149	47%	0.466	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-82.1	154.1	168	-64	-85.5	0	0	0	110.5	R359 D371 L390 D394	R359-Y392 HydrophobicContact CB-CD1 3.88Å; R359-Y392 HydrophobicContact CB-CG 3.98Å; R359-Y392 HydrophobicContact CG-CD1 4.36Å; R359-Y392 HydrophobicContact CG-CG 4.31Å; D371-Y392 PolarHBondContact OD1-OH 3.07Å; D371-Y392 VanDerWaalsContact OD1-OH 3.04Å; L390-Y392 HydrophobicContact CB-CD2 4.47Å; L390-Y392 HydrophobicContact CB-CE2 3.9Å; Y392-D394 PolarHBondContact O-N 3.13Å
393	K	47.6	Very low	43.1	Very low	96 Å²	96	94.3 Å²	94.3	42%	0.417	48%	0.482	S	S	.	.			trans	-76.1	105.9	172.5	-167.6	166.7	-176.9	177.3	0	109.1	D356	D356-K393 WeakPolarHBondContact OD1-CD 3.33Å; D356-K393 WeakPolarHBondContact OD1-CE 3.2Å; D356-K393 IonicContact OD1-NZ 2.71Å; D356-K393 PolarHBondContact OD1-NZ 3.4Å; D356-K393 IonicContact OD2-NZ 2.78Å
394	D	44.6	Very low	42.2	Very low	79 Å²	79	97 Å²	97	42%	0.422	48%	0.476	S	S	.	.			trans	-79.1	125.6	174.2	-88.8	-40.9	0	0	0	110.5	R359 Y392 A396 M397	R359-D394 IonicContact CZ-OD1 2.69Å; R359-D394 IonicContact NH2-OD1 2.69Å; R359-D394 PolarHBondContact NH2-OD1 3.2Å; R359-D394 IonicContact NH2-OD2 3.78Å; R359-D394 PolarHBondContact NH2-OD2 2.85Å; Y392-D394 PolarHBondContact O-N 3.13Å; D394-A396 PolarHBondContact O-N 3.12Å; D394-M397 PolarHBondContact O-N 3.46Å
395	D	45	Very low	41.8	Very low	65 Å²	65	101.5 Å²	101.5	35%	0.348	49%	0.493	S	S	.	.	H	α-helix	trans	-56.4	-20.9	179.5	-57.7	-68.5	0	0	0	113.6	N360 M397 V398 H399	N360-D395 WeakPolarHBondContact CB-OD2 3.49Å; N360-D395 PolarHBondContact ND2-OD2 3.19Å; D395-M397 VanDerWaalsContact C-N 3.31Å; D395-M397 PolarHBondContact O-N 2.89Å; D395-V398 PolarHBondContact O-N 3.49Å; D395-H399 PolarHBondContact O-N 3.41Å
396	A	43.7	Very low	41.1	Very low	71 Å²	71	99.6 Å²	99.6	59%	0.587	49%	0.49	S	S	*	.	H	α-helix	trans	-54.2	-44.6	177.5	0	0	0	0	0	112.4	D394 V398 E400	D394-A396 PolarHBondContact O-N 3.12Å; A396-V398 VanDerWaalsContact C-N 3.33Å; A396-E400 WeakPolarHBondContact O-CB 3.33Å; A396-E400 PolarHBondContact O-N 3.41Å; A396-E400 VanDerWaalsContact O-N 3.16Å
397	M	36.2	Very low	40.8	Very low	141 Å²	141	100.9 Å²	100.9	70%	0.695	50%	0.498	S	S	*	.	H	α-helix	trans	-77.5	-17.8	177.3	-71.2	-162.9	120.9	0	0	113.4	D394 D395 R401	D394-M397 PolarHBondContact O-N 3.46Å; D395-M397 VanDerWaalsContact C-N 3.31Å; D395-M397 PolarHBondContact O-N 2.89Å; M397-R401 VanDerWaalsContact O-CB 3.23Å; M397-R401 WeakPolarHBondContact O-CB 3.2Å; M397-R401 PolarHBondContact O-N 2.98Å
398	V	39.3	Very low	40.1	Very low	60 Å²	60	108.2 Å²	108.2	36%	0.364	53%	0.532	S	S	.	.	H	α-helix	trans	-77.8	-42	176.2	179.2	0	0	0	0	110.1	D395 A396 L402	D395-V398 PolarHBondContact O-N 3.49Å; A396-V398 VanDerWaalsContact C-N 3.33Å; V398-L402 HydrophobicContact CG1-CD1 4.1Å; V398-L402 WeakPolarHBondContact O-CB 3.48Å; V398-L402 PolarHBondContact O-N 3.23Å
399	H	33.1	Very low	39.7	Very low	139 Å²	139	112.5 Å²	112.5	64%	0.644	55%	0.551	S	S	*	*	H	α-helix	trans	-64.7	-46.8	172.4	-115.7	45.7	0	0	0	112.1	D395 R401 L402 E403	D395-H399 PolarHBondContact O-N 3.41Å; H399-R401 PolarHBondContact O-N 2.86Å; H399-L402 PolarHBondContact O-N 3.02Å; H399-L402 VanDerWaalsContact O-N 3.13Å; H399-E403 PolarHBondContact O-N 3.33Å
400	E	35.2	Very low	39.2	Very low	122 Å²	122	109.8 Å²	109.8	57%	0.57	55%	0.548	S	S	*	.	H	α-helix	trans	-63	-29.8	179.9	-166.2	171.7	-141	0	0	112.6	A396	A396-E400 WeakPolarHBondContact O-CB 3.33Å; A396-E400 PolarHBondContact O-N 3.41Å; A396-E400 VanDerWaalsContact O-N 3.16Å
401	R	31.7	Very low	38.4	Very low	166 Å²	166	114.1 Å²	114.1	63%	0.626	57%	0.569	S	S	*	*	H	α-helix	trans	-79.4	-36.2	173.3	-171.6	-177.3	-115.2	-96	5.8	113	M397 H399 Y404 E405	M397-R401 VanDerWaalsContact O-CB 3.23Å; M397-R401 WeakPolarHBondContact O-CB 3.2Å; M397-R401 PolarHBondContact O-N 2.98Å; H399-R401 PolarHBondContact O-N 2.86Å; R401-Y404 PolarHBondContact O-N 3.17Å; R401-E405 IonicContact NH1-OE1 3.25Å; R401-E405 PolarHBondContact NH1-OE1 3.15Å; R401-E405 PolarHBondContact O-N 3.25Å
402	L	32.4	Very low	37.9	Very low	91 Å²	91	114.8 Å²	114.8	48%	0.476	57%	0.572	S	S	.	*	H	α-helix	trans	-67.6	-40.5	176	-96.3	153.1	0	0	0	112	V398 H399 Y404 E405 T406	V398-L402 HydrophobicContact CG1-CD1 4.1Å; V398-L402 WeakPolarHBondContact O-CB 3.48Å; V398-L402 PolarHBondContact O-N 3.23Å; H399-L402 PolarHBondContact O-N 3.02Å; H399-L402 VanDerWaalsContact O-N 3.13Å; L402-Y404 VanDerWaalsContact C-N 3.26Å; L402-Y404 PolarHBondContact O-N 3.04Å; L402-E405 PolarHBondContact O-N 2.97Å; L402-T406 WeakPolarHBondContact O-CG2 3.49Å; L402-T406 PolarHBondContact O-N 3.1Å; L402-T406 PolarHBondContact O-OG1 3.34Å
403	E	31.3	Very low	37	Very low	133 Å²	133	119.6 Å²	119.6	62%	0.621	60%	0.599	S	S	*	*	H	α-helix	trans	-60.7	-36.7	172.4	-77.6	-173.9	132.2	0	0	111.8	H399 T406 T407	H399-E403 PolarHBondContact O-N 3.33Å; E403-T406 PolarHBondContact O-OG1 2.93Å; E403-T407 WeakPolarHBondContact O-CG2 3.47Å; E403-T407 PolarHBondContact O-N 3.11Å; E403-T407 PolarHBondContact O-OG1 3.34Å
404	Y	31	Very low	36.2	Very low	179 Å²	179	121.1 Å²	121.1	70%	0.702	61%	0.611	S	S	*	*	H	α-helix	trans	-71.4	-34.7	175.7	-110.2	-84.9	0	0	0	114.3	R401 L402 T406	R401-Y404 PolarHBondContact O-N 3.17Å; L402-Y404 VanDerWaalsContact C-N 3.26Å; L402-Y404 PolarHBondContact O-N 3.04Å; Y404-T406 VanDerWaalsContact C-N 3.34Å
405	E	36.2	Very low	35.7	Very low	130 Å²	130	124.1 Å²	124.1	61%	0.607	62%	0.624	S	S	*	*	H	α-helix	trans	-80.5	-12.7	176.5	-75.3	175.9	-167.1	0	0	112.8	R401 L402	R401-E405 IonicContact NH1-OE1 3.25Å; R401-E405 PolarHBondContact NH1-OE1 3.15Å; R401-E405 PolarHBondContact O-N 3.25Å; L402-E405 PolarHBondContact O-N 2.97Å
406	T	33.2	Very low	34.9	Very low	107 Å²	107	128.7 Å²	128.7	66%	0.656	65%	0.646	S	S	*	*	T	Hydrogen-bonded Turn	trans	-101	4.8	174	58	0	0	0	0	115.2	L402 E403 Y404	L402-T406 WeakPolarHBondContact O-CG2 3.49Å; L402-T406 PolarHBondContact O-N 3.1Å; L402-T406 PolarHBondContact O-OG1 3.34Å; E403-T406 PolarHBondContact O-OG1 2.93Å; Y404-T406 VanDerWaalsContact C-N 3.34Å
407	T	37.5	Very low	34.2	Very low	107 Å²	107	133.5 Å²	133.5	66%	0.656	65%	0.651	S	S	*	*			trans	-121.8	31.8	-179.1	49.1	0	0	0	0	114.1	E403	E403-T407 WeakPolarHBondContact O-CG2 3.47Å; E403-T407 PolarHBondContact O-N 3.11Å; E403-T407 PolarHBondContact O-OG1 3.34Å
408	L	33.3	Very low	34	Very low	227 Å²	227	132.8 Å²	132.8	100%	1.188	65%	0.647	S	S	*	*			trans	-119.7	0	169.8	-95.3	165.2	0	0	0	111.8

Retrieved 408 of 408 residues in 139.8 ms (Link to these results)

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