A0A096M7I2_POEFO Loading...

Bleomycin hydrolase

AlphaFold DB , UniProt , Accession A0A096M7I2, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 452 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M60.7Low90.1Very high242 Ų242113.3 Ų113.3100%1.19266%0.66SS**  0118.20-88.2-177.6-93.600106.1
2D74.4Confident90.7Very high149 Ų149110 Ų11080%0.79764%0.643SS**  trans-64.3137.7171-63.8-33.2000108.6G4D2-G4 PolarHBondContact O-N 3.26Å
3A90Very high91.3Very high107 Ų107109 Ų10988%0.88463%0.626SS**SBendtrans-68.4124.9174.800000109.1
4G92.6Very high91.7Very high69 Ų69105 Ų10571%0.71160%0.604SS**SBendtrans83.8-165.2173.100000115.4D2D2-G4 PolarHBondContact O-N 3.26Å
5L94.9Very high92.1Very high117 Ų117109 Ų10961%0.61361%0.612SS**SBendtrans-77.8128.3-175.8-17563.3000110.8P7 V10L5-P7 WeakPolarHBondContact O-CD 3.26Å; L5-V10 HydrophobicContact CD2-CG2 3.4Å; L5-V10 VanDerWaalsContact CD2-CG2 3.4Å; L5-V10 HydrophobicContact CG-CG2 3.71Å
6S95.5Very high92.4Very high32 Ų32111.8 Ų111.822%0.22461%0.61CS.*  trans-56.8125.2178.1165.80000112.1E8 K9 V10S6-E8 PolarHBondContact O-N 3.38Å; S6-E8 PolarHBondContact OG-N 3.02Å; S6-K9 WeakPolarHBondContact O-CB 3.36Å; S6-K9 PolarHBondContact O-N 3.35Å; S6-K9 VanDerWaalsContact O-N 3.12Å; S6-K9 PolarHBondContact OG-N 3.11Å; S6-V10 PolarHBondContact O-N 3.42Å; S6-V10 VanDerWaalsContact O-N 3.07Å
7P95.3Very high92.7Very high98 Ų98108.7 Ų108.764%0.63659%0.592SS**Hα-helixtrans-58.9-33.4177.1-26.635.4000113.9L5 V10 T11L5-P7 WeakPolarHBondContact O-CD 3.26Å; P7-V10 PolarHBondContact O-N 2.96Å; P7-T11 PolarHBondContact O-N 3.32Å; P7-T11 PolarHBondContact O-OG1 3.26Å
8E96.1Very high92.9Very high153 Ų153111.9 Ų111.972%0.71559%0.594SS**Hα-helixtrans-66.4-41.2176.7-63.5-179.6173.700111.5S6 T11 T12S6-E8 PolarHBondContact O-N 3.38Å; S6-E8 PolarHBondContact OG-N 3.02Å; E8-T11 PolarHBondContact O-N 3.03Å; E8-T12 WeakPolarHBondContact O-CB 3.47Å; E8-T12 PolarHBondContact O-N 3.48Å; E8-T12 PolarHBondContact O-OG1 3.23Å
9K96.6Very high93.2Very high125 Ų125110.6 Ų110.654%0.54360%0.595SS.*Hα-helixtrans-63.4-44.7173.8-70-175179.8177.80111.2S6 T11 T12 F13S6-K9 WeakPolarHBondContact O-CB 3.36Å; S6-K9 PolarHBondContact O-N 3.35Å; S6-K9 VanDerWaalsContact O-N 3.12Å; S6-K9 PolarHBondContact OG-N 3.11Å; K9-T11 VanDerWaalsContact C-N 3.35Å; K9-T11 PolarHBondContact O-N 3.3Å; K9-T12 WeakPolarHBondContact O-CB 3.3Å; K9-T12 PolarHBondContact O-N 2.94Å; K9-T12 VanDerWaalsContact O-N 3.16Å; K9-F13 HydrophobicContact CB-CE2 4.1Å; K9-F13 HydrophobicContact CB-CZ 4Å; K9-F13 WeakPolarHBondContact O-CD1 3.47Å; K9-F13 WeakPolarHBondContact O-CD2 3.39Å; K9-F13 WeakPolarHBondContact O-CG 3.34Å; K9-F13 PolarHBondContact O-N 3.45Å
10V97.3Very high93.4Very high58 Ų58108.4 Ų108.435%0.35258%0.581SS.*Hα-helixtrans-56.5-49.7176.5175.70000110.9L5 S6 P7 T12 F13 T14L5-V10 HydrophobicContact CD2-CG2 3.4Å; L5-V10 VanDerWaalsContact CD2-CG2 3.4Å; L5-V10 HydrophobicContact CG-CG2 3.71Å; S6-V10 PolarHBondContact O-N 3.42Å; S6-V10 VanDerWaalsContact O-N 3.07Å; P7-V10 PolarHBondContact O-N 2.96Å; V10-T12 VanDerWaalsContact C-N 3.26Å; V10-T12 PolarHBondContact O-N 3.38Å; V10-F13 PolarHBondContact O-N 2.98Å; V10-F13 VanDerWaalsContact O-N 3.15Å; V10-T14 PolarHBondContact O-N 3.48Å; V10-T14 PolarHBondContact O-OG1 3.21Å; V10-T14 VanDerWaalsContact O-OG1 3.14Å
11T97.6Very high93.6Very high96 Ų96108.2 Ų108.259%0.58959%0.586SS**Hα-helixtrans-58.3-41.9178.7-57.70000111.2P7 E8 K9 K15P7-T11 PolarHBondContact O-N 3.32Å; P7-T11 PolarHBondContact O-OG1 3.26Å; E8-T11 PolarHBondContact O-N 3.03Å; K9-T11 VanDerWaalsContact C-N 3.35Å; K9-T11 PolarHBondContact O-N 3.3Å; T11-K15 WeakPolarHBondContact O-CB 3.39Å; T11-K15 PolarHBondContact O-N 3.05Å
12T98Very high95.2Very high74 Ų74102.7 Ų102.745%0.45455%0.552SS.*Hα-helixtrans-63.5-44.5176.8-58.60000112E8 K9 V10 K15 R16E8-T12 WeakPolarHBondContact O-CB 3.47Å; E8-T12 PolarHBondContact O-N 3.48Å; E8-T12 PolarHBondContact O-OG1 3.23Å; K9-T12 WeakPolarHBondContact O-CB 3.3Å; K9-T12 PolarHBondContact O-N 2.94Å; K9-T12 VanDerWaalsContact O-N 3.16Å; V10-T12 VanDerWaalsContact C-N 3.26Å; V10-T12 PolarHBondContact O-N 3.38Å; T12-K15 PolarHBondContact O-N 3.15Å; T12-R16 PolarHBondContact O-N 3.5Å; T12-R16 VanDerWaalsContact O-N 3.07Å
13F97.3Very high96.3Very high97 Ų9799.1 Ų99.143%0.42553%0.528SS..Hα-helixtrans-62.6-49.1177.1-58.3-24.6000111.3K9 V10 K15 R16 L17K9-F13 HydrophobicContact CB-CE2 4.1Å; K9-F13 HydrophobicContact CB-CZ 4Å; K9-F13 WeakPolarHBondContact O-CD1 3.47Å; K9-F13 WeakPolarHBondContact O-CD2 3.39Å; K9-F13 WeakPolarHBondContact O-CG 3.34Å; K9-F13 PolarHBondContact O-N 3.45Å; V10-F13 PolarHBondContact O-N 2.98Å; V10-F13 VanDerWaalsContact O-N 3.15Å; F13-K15 VanDerWaalsContact C-N 3.32Å; F13-K15 PolarHBondContact O-N 3.01Å; F13-R16 PolarHBondContact O-N 3.49Å; F13-R16 VanDerWaalsContact O-N 3.17Å; F13-L17 WeakPolarHBondContact O-CG 3.17Å; F13-L17 PolarHBondContact O-N 2.63Å
14T96.9Very high96.7Very high53 Ų5397.2 Ų97.233%0.32550%0.502SS..Hα-helixtrans-60.3-41.9179-56.60000111.8V10 R16 L17 R18V10-T14 PolarHBondContact O-N 3.48Å; V10-T14 PolarHBondContact O-OG1 3.21Å; V10-T14 VanDerWaalsContact O-OG1 3.14Å; T14-R16 VanDerWaalsContact C-N 3.35Å; T14-R16 PolarHBondContact O-N 3.21Å; T14-L17 PolarHBondContact O-N 3Å; T14-R18 HydrophobicContact CG2-CG 4.31Å; T14-R18 WeakPolarHBondContact O-CB 3.48Å; T14-R18 VanDerWaalsContact O-CG 3.3Å; T14-R18 WeakPolarHBondContact O-CG 3.27Å; T14-R18 PolarHBondContact O-N 3.21Å
15K97.9Very high97Very high165 Ų16599.3 Ų99.372%0.71750%0.497SS*.Hα-helixtrans-61.9-43176.8-173.9178.1179.1-179.20111.5T11 T12 F13 S19T11-K15 WeakPolarHBondContact O-CB 3.39Å; T11-K15 PolarHBondContact O-N 3.05Å; T12-K15 PolarHBondContact O-N 3.15Å; F13-K15 VanDerWaalsContact C-N 3.32Å; F13-K15 PolarHBondContact O-N 3.01Å; K15-S19 PolarHBondContact O-N 2.81Å
16R97.4Very high97.1Very high153 Ų15394.4 Ų94.458%0.57747%0.472SS*.Hα-helixtrans-63.1-51.8177.2-172.3-178.8-60.7176.30.8111.4T12 F13 T14 R18 S19T12-R16 PolarHBondContact O-N 3.5Å; T12-R16 VanDerWaalsContact O-N 3.07Å; F13-R16 PolarHBondContact O-N 3.49Å; F13-R16 VanDerWaalsContact O-N 3.17Å; T14-R16 VanDerWaalsContact C-N 3.35Å; T14-R16 PolarHBondContact O-N 3.21Å; R16-R18 PolarHBondContact O-N 3.06Å; R16-S19 WeakPolarHBondContact O-CB 3.4Å; R16-S19 PolarHBondContact O-N 3.4Å; R16-S19 PolarHBondContact O-OG 2.94Å
17L97.2Very high97.2Very high60 Ų6096.5 Ų96.531%0.31448%0.479SS..Hα-helixtrans-60.6-43-179.7-66.7172.5000112F13 T14 S19 E20 Y23F13-L17 WeakPolarHBondContact O-CG 3.17Å; F13-L17 PolarHBondContact O-N 2.63Å; T14-L17 PolarHBondContact O-N 3Å; L17-S19 PolarHBondContact O-N 3.36Å; L17-E20 WeakPolarHBondContact O-CB 3.46Å; L17-E20 PolarHBondContact O-N 3.32Å; L17-Y23 HydrophobicContact CB-CD1 3.76Å; L17-Y23 HydrophobicContact CB-CD2 4.1Å; L17-Y23 HydrophobicContact CB-CE1 3.66Å; L17-Y23 HydrophobicContact CB-CE2 4Å; L17-Y23 HydrophobicContact CB-CG 3.98Å; L17-Y23 HydrophobicContact CD1-CE2 3.92Å; L17-Y23 HydrophobicContact CD2-CD2 3.78Å; L17-Y23 HydrophobicContact CD2-CE2 3.89Å; L17-Y23 HydrophobicContact CD2-CG 4.3Å; L17-Y23 HydrophobicContact CG-CD2 4.37Å; L17-Y23 HydrophobicContact CG-CE2 4.15Å; L17-Y23 WeakPolarHBondContact O-CB 3.29Å; L17-Y23 WeakPolarHBondContact O-CD1 3.31Å
18R97.1Very high97.3Very high166 Ų16696.9 Ų96.963%0.62648%0.475SS*.Hα-helixtrans-66-19176.1-73.1180179.7173.11.3113.9T14 R16 E20 L24T14-R18 HydrophobicContact CG2-CG 4.31Å; T14-R18 WeakPolarHBondContact O-CB 3.48Å; T14-R18 VanDerWaalsContact O-CG 3.3Å; T14-R18 WeakPolarHBondContact O-CG 3.27Å; T14-R18 PolarHBondContact O-N 3.21Å; R16-R18 PolarHBondContact O-N 3.06Å; R18-E20 VanDerWaalsContact C-N 3.31Å; R18-L24 HydrophobicContact CG-CD2 4.46Å
19S97.4Very high97.4Very high88 Ų8892 Ų9262%0.61546%0.456SS*.THydrogen-bonded Turntrans-83.5-7.2174.772.50000113.5K15 R16 L17 P21K15-S19 PolarHBondContact O-N 2.81Å; R16-S19 WeakPolarHBondContact O-CB 3.4Å; R16-S19 PolarHBondContact O-N 3.4Å; R16-S19 PolarHBondContact O-OG 2.94Å; L17-S19 PolarHBondContact O-N 3.36Å; S19-P21 WeakPolarHBondContact O-CD 3.19Å
20E97.1Very high97.5Very high65 Ų6587.2 Ų87.230%0.30444%0.439SS..  trans-96.7109.6179.1-66174.6-146.300110.4L17 R18 R22 Y23 L24L17-E20 WeakPolarHBondContact O-CB 3.46Å; L17-E20 PolarHBondContact O-N 3.32Å; R18-E20 VanDerWaalsContact C-N 3.31Å; E20-R22 PolarHBondContact O-N 3.48Å; E20-Y23 WeakPolarHBondContact O-CB 3.45Å; E20-Y23 PolarHBondContact O-N 3.03Å; E20-L24 PolarHBondContact O-N 2.92Å; E20-L24 VanDerWaalsContact O-N 3.15Å
21P97.5Very high97.5Very high106 Ų10689.5 Ų89.569%0.68845%0.453SS*.Hα-helixtrans-58.7-36-178.6-26.235.4000113.3S19 Y23 L24 L25S19-P21 WeakPolarHBondContact O-CD 3.19Å; P21-Y23 VanDerWaalsContact C-N 3.33Å; P21-Y23 PolarHBondContact O-N 3.24Å; P21-L24 PolarHBondContact O-N 3.14Å; P21-L25 PolarHBondContact O-N 3.17Å
22R95.8Very high97.5Very high126 Ų12690 Ų9048%0.47546%0.459SS..Hα-helixtrans-61-41.6175.1-176.4-17965.5-178.8-2.2111.8E20 L25 A26 L347E20-R22 PolarHBondContact O-N 3.48Å; R22-L25 PolarHBondContact O-N 3.48Å; R22-A26 WeakPolarHBondContact O-CB 3.14Å; R22-A26 PolarHBondContact O-N 3.37Å; R22-L347 WeakPolarHBondContact CD-O 3.47Å
23Y96.9Very high97.4Very high74 Ų7491.1 Ų91.129%0.2946%0.461SS..Hα-helixtrans-64.3-43.9177175-91.7000111.3L17 E20 P21 L25 A26 Q27L17-Y23 HydrophobicContact CB-CD1 3.76Å; L17-Y23 HydrophobicContact CB-CD2 4.1Å; L17-Y23 HydrophobicContact CB-CE1 3.66Å; L17-Y23 HydrophobicContact CB-CE2 4Å; L17-Y23 HydrophobicContact CB-CG 3.98Å; L17-Y23 HydrophobicContact CD1-CE2 3.92Å; L17-Y23 HydrophobicContact CD2-CD2 3.78Å; L17-Y23 HydrophobicContact CD2-CE2 3.89Å; L17-Y23 HydrophobicContact CD2-CG 4.3Å; L17-Y23 HydrophobicContact CG-CD2 4.37Å; L17-Y23 HydrophobicContact CG-CE2 4.15Å; L17-Y23 WeakPolarHBondContact O-CB 3.29Å; L17-Y23 WeakPolarHBondContact O-CD1 3.31Å; E20-Y23 WeakPolarHBondContact O-CB 3.45Å; E20-Y23 PolarHBondContact O-N 3.03Å; P21-Y23 VanDerWaalsContact C-N 3.33Å; P21-Y23 PolarHBondContact O-N 3.24Å; Y23-L25 VanDerWaalsContact C-N 3.35Å; Y23-L25 PolarHBondContact O-N 3.35Å; Y23-A26 PolarHBondContact O-N 3.13Å; Y23-Q27 VanDerWaalsContact O-CB 3.27Å; Y23-Q27 WeakPolarHBondContact O-CB 3.44Å; Y23-Q27 PolarHBondContact O-N 3.33Å
24L98Very high97.4Very high66 Ų6690.8 Ų90.835%0.34646%0.464SS..Hα-helixtrans-62.9-41.2177.2-66178.2000112.1R18 E20 P21 Q27 N28R18-L24 HydrophobicContact CG-CD2 4.46Å; E20-L24 PolarHBondContact O-N 2.92Å; E20-L24 VanDerWaalsContact O-N 3.15Å; P21-L24 PolarHBondContact O-N 3.14Å; L24-Q27 PolarHBondContact O-N 3.02Å; L24-N28 VanDerWaalsContact O-CG 3.26Å; L24-N28 PolarHBondContact O-N 3.34Å; L24-N28 PolarHBondContact O-ND2 3.44Å
25L98.1Very high97.2Very high114 Ų11490.9 Ų90.960%0.59747%0.465SS*.Hα-helixtrans-60.9-52.1174.5176.461.8000111.1P21 R22 Y23 Q27 N28 V29P21-L25 PolarHBondContact O-N 3.17Å; R22-L25 PolarHBondContact O-N 3.48Å; Y23-L25 VanDerWaalsContact C-N 3.35Å; Y23-L25 PolarHBondContact O-N 3.35Å; L25-Q27 VanDerWaalsContact C-N 3.3Å; L25-Q27 PolarHBondContact O-N 3.12Å; L25-N28 PolarHBondContact O-N 2.92Å; L25-V29 WeakPolarHBondContact O-CG2 3.37Å; L25-V29 PolarHBondContact O-N 3.12Å
26A97.8Very high96.9Very high13 Ų1387 Ų8711%0.10745%0.452CS..Hα-helixtrans-59.1-41.4178.300000111.8R22 Y23 V29 S30 V348R22-A26 WeakPolarHBondContact O-CB 3.14Å; R22-A26 PolarHBondContact O-N 3.37Å; Y23-A26 PolarHBondContact O-N 3.13Å; A26-V29 WeakPolarHBondContact O-CG2 3.4Å; A26-V29 PolarHBondContact O-N 3.24Å; A26-S30 WeakPolarHBondContact O-CB 3.39Å; A26-S30 PolarHBondContact O-N 2.79Å; A26-S30 PolarHBondContact O-OG 2.92Å; A26-V348 HydrophobicContact CB-CG1 4.16Å; A26-V348 WeakPolarHBondContact CB-O 3.33Å
27Q98.1Very high96.8Very high77 Ų7783 Ų8336%0.3644%0.44SS..Hα-helixtrans-59-49.1175.6177.1168.37300111.5Y23 L24 L25 V29 T31Y23-Q27 VanDerWaalsContact O-CB 3.27Å; Y23-Q27 WeakPolarHBondContact O-CB 3.44Å; Y23-Q27 PolarHBondContact O-N 3.33Å; L24-Q27 PolarHBondContact O-N 3.02Å; L25-Q27 VanDerWaalsContact C-N 3.3Å; L25-Q27 PolarHBondContact O-N 3.12Å; Q27-V29 VanDerWaalsContact C-N 3.33Å; Q27-V29 PolarHBondContact O-N 3.26Å; Q27-T31 HydrophobicContact CG-CG2 4.4Å; Q27-T31 VanDerWaalsContact O-CG2 3.26Å; Q27-T31 WeakPolarHBondContact O-CG2 3.35Å; Q27-T31 PolarHBondContact O-N 2.78Å; Q27-T31 VanDerWaalsContact O-N 3.11Å; Q27-T31 PolarHBondContact O-OG1 3.38Å
28N98.1Very high96.8Very high105 Ų10581.9 Ų81.956%0.56144%0.435SS*.Hα-helixtrans-60.8-39.1-177.5-73.2-20.6000113.3L24 L25 T31 C32L24-N28 VanDerWaalsContact O-CG 3.26Å; L24-N28 PolarHBondContact O-N 3.34Å; L24-N28 PolarHBondContact O-ND2 3.44Å; L25-N28 PolarHBondContact O-N 2.92Å; N28-T31 PolarHBondContact O-OG1 3.25Å; N28-C32 PolarHBondContact O-SG 3.47Å
29V97.9Very high96.8Very high51 Ų5174.1 Ų74.131%0.30941%0.406SS..Hα-helixtrans-80.9-44.5-179.2-62.50000111.8L25 A26 Q27 T31 C32 I33 V38L25-V29 WeakPolarHBondContact O-CG2 3.37Å; L25-V29 PolarHBondContact O-N 3.12Å; A26-V29 WeakPolarHBondContact O-CG2 3.4Å; A26-V29 PolarHBondContact O-N 3.24Å; Q27-V29 VanDerWaalsContact C-N 3.33Å; Q27-V29 PolarHBondContact O-N 3.26Å; V29-T31 VanDerWaalsContact C-N 3.27Å; V29-T31 PolarHBondContact O-N 3.47Å; V29-C32 PolarHBondContact O-N 3.46Å; V29-I33 PolarHBondContact O-N 3.34Å; V29-V38 HydrophobicContact CB-CG1 4.48Å; V29-V38 HydrophobicContact CB-CG2 4.29Å; V29-V38 HydrophobicContact CG2-CG1 3.53Å; V29-V38 HydrophobicContact CG2-CG2 4.14Å
30S97.4Very high96.9Very high25 Ų2572.1 Ų72.118%0.17539%0.389CS..Hα-helixtrans-72.5-15.9-176.1-60.60000113.6A26 C32A26-S30 WeakPolarHBondContact O-CB 3.39Å; A26-S30 PolarHBondContact O-N 2.79Å; A26-S30 PolarHBondContact O-OG 2.92Å; S30-C32 VanDerWaalsContact C-N 3.31Å
31T97.7Very high96.9Very high106 Ų10672.2 Ų72.265%0.6539%0.389SS*.THydrogen-bonded Turntrans-79.9-12.9169.852.70000113.5Q27 N28 V29Q27-T31 HydrophobicContact CG-CG2 4.4Å; Q27-T31 VanDerWaalsContact O-CG2 3.26Å; Q27-T31 WeakPolarHBondContact O-CG2 3.35Å; Q27-T31 PolarHBondContact O-N 2.78Å; Q27-T31 VanDerWaalsContact O-N 3.11Å; Q27-T31 PolarHBondContact O-OG1 3.38Å; N28-T31 PolarHBondContact O-OG1 3.25Å; V29-T31 VanDerWaalsContact C-N 3.27Å; V29-T31 PolarHBondContact O-N 3.47Å
32C97.3Very high96.9Very high107 Ų10775.5 Ų75.572%0.72339%0.387SS*.THydrogen-bonded Turntrans-115-19.5-174.3-58.90000113.3N28 V29 S30N28-C32 PolarHBondContact O-SG 3.47Å; V29-C32 PolarHBondContact O-N 3.46Å; S30-C32 VanDerWaalsContact C-N 3.31Å
33I97.1Very high97Very high96 Ų9673.8 Ų73.849%0.49239%0.385SS..SBendtrans-134151.8-173.4-57.7177.6000108.6V29 E37 V38V29-I33 PolarHBondContact O-N 3.34Å; I33-E37 HydrophobicContact CG2-CB 4.01Å; I33-V38 HydrophobicContact CB-CG2 3.97Å; I33-V38 HydrophobicContact CG2-CG2 4.08Å
34D95.9Very high97.1Very high90 Ų9071 Ų7148%0.48138%0.375SS..  trans-49.8127.7170.5-177.7-79.9000110.9L36 E37 V38D34-L36 VanDerWaalsContact C-N 3.28Å; D34-L36 PolarHBondContact O-N 3.27Å; D34-L36 WeakPolarHBondContact OD1-CA 3.47Å; D34-L36 VanDerWaalsContact OD1-CB 3.29Å; D34-L36 WeakPolarHBondContact OD1-CB 3.47Å; D34-L36 PolarHBondContact OD1-N 3.01Å; D34-E37 HydrophobicContact CB-CB 4.31Å; D34-E37 HydrophobicContact CB-CG 3.96Å; D34-E37 WeakPolarHBondContact O-CB 3.37Å; D34-E37 PolarHBondContact O-N 3.47Å; D34-E37 VanDerWaalsContact O-N 3.13Å; D34-E37 PolarHBondContact OD1-N 2.72Å; D34-V38 PolarHBondContact O-N 3.47Å; D34-V38 VanDerWaalsContact O-N 3.14Å
35P94.1Very high97.1Very high56 Ų5669.1 Ų69.136%0.36437%0.367SS..Hα-helixtrans-67.1-22.6-173.3-17.828.2000114.9C39 F349P35-C39 WeakPolarHBondContact O-CB 3.2Å; P35-C39 PolarHBondContact O-N 2.92Å; P35-C39 PolarHBondContact O-SG 3.43Å; P35-F349 HydrophobicContact CB-CZ 3.78Å
36L90.3Very high97Very high83 Ų8369.2 Ų69.244%0.43536%0.364SS..Hα-helixtrans-72.3-37.7173.1-67.4177.8000111.3D34 V38 C39 L40 F343D34-L36 VanDerWaalsContact C-N 3.28Å; D34-L36 PolarHBondContact O-N 3.27Å; D34-L36 WeakPolarHBondContact OD1-CA 3.47Å; D34-L36 VanDerWaalsContact OD1-CB 3.29Å; D34-L36 WeakPolarHBondContact OD1-CB 3.47Å; D34-L36 PolarHBondContact OD1-N 3.01Å; L36-V38 VanDerWaalsContact C-N 3.3Å; L36-V38 PolarHBondContact O-N 3.45Å; L36-C39 CarbonylContact O-C 3.59Å; L36-C39 PolarHBondContact O-N 2.98Å; L36-C39 VanDerWaalsContact O-N 3.17Å; L36-L40 PolarHBondContact O-N 3.44Å; L36-L40 VanDerWaalsContact O-N 3.12Å; L36-F343 HydrophobicContact CB-CD1 4.47Å; L36-F343 HydrophobicContact CB-CE1 3.94Å; L36-F343 HydrophobicContact CB-CZ 4.12Å; L36-F343 HydrophobicContact CD2-CD2 4.24Å; L36-F343 HydrophobicContact CD2-CE2 4.24Å; L36-F343 HydrophobicContact CD2-CG 4.4Å; L36-F343 HydrophobicContact CD2-CZ 4.39Å; L36-F343 WeakPolarHBondContact O-CD1 3.42Å; L36-F343 VanDerWaalsContact O-CE1 3.26Å; L36-F343 WeakPolarHBondContact O-CE1 3.33Å
37E95.9Very high97Very high70 Ų7073.3 Ų73.333%0.32738%0.384SS..Hα-helixtrans-64-37.2173.6-63.5-80.8-18000110.8I33 D34 L40 H332 K334I33-E37 HydrophobicContact CG2-CB 4.01Å; D34-E37 HydrophobicContact CB-CB 4.31Å; D34-E37 HydrophobicContact CB-CG 3.96Å; D34-E37 WeakPolarHBondContact O-CB 3.37Å; D34-E37 PolarHBondContact O-N 3.47Å; D34-E37 VanDerWaalsContact O-N 3.13Å; D34-E37 PolarHBondContact OD1-N 2.72Å; E37-L40 VanDerWaalsContact O-CB 3.31Å; E37-L40 WeakPolarHBondContact O-CB 3.46Å; E37-L40 PolarHBondContact O-N 3.38Å; E37-H332 IonicContact OE1-NE2 3.05Å; E37-H332 IonicContact OE2-NE2 3.44Å; E37-K334 IonicContact OE1-NZ 3.52Å; E37-K334 PolarHBondContact OE1-NZ 2.83Å
38V97.3Very high96.9Very high36 Ų3671.1 Ų71.122%0.21838%0.376CS..Hα-helixtrans-64.7-39.5171.9175.30000111.8V29 I33 D34 L36 L40 V348V29-V38 HydrophobicContact CB-CG1 4.48Å; V29-V38 HydrophobicContact CB-CG2 4.29Å; V29-V38 HydrophobicContact CG2-CG1 3.53Å; V29-V38 HydrophobicContact CG2-CG2 4.14Å; I33-V38 HydrophobicContact CB-CG2 3.97Å; I33-V38 HydrophobicContact CG2-CG2 4.08Å; D34-V38 PolarHBondContact O-N 3.47Å; D34-V38 VanDerWaalsContact O-N 3.14Å; L36-V38 VanDerWaalsContact C-N 3.3Å; L36-V38 PolarHBondContact O-N 3.45Å; V38-L40 PolarHBondContact O-N 3.32Å; V38-V348 HydrophobicContact CG1-CG1 3.96Å; V38-V348 HydrophobicContact CG1-CG2 4.17Å
39C97.7Very high96.8Very high2 Ų269.8 Ų69.81%0.01437%0.372CS..Hα-helixtrans-72.7-10.2178.4-75.10000113.9P35 L36 H41 F343 N344 V348 F349P35-C39 WeakPolarHBondContact O-CB 3.2Å; P35-C39 PolarHBondContact O-N 2.92Å; P35-C39 PolarHBondContact O-SG 3.43Å; L36-C39 CarbonylContact O-C 3.59Å; L36-C39 PolarHBondContact O-N 2.98Å; L36-C39 VanDerWaalsContact O-N 3.17Å; C39-H41 PolarHBondContact O-N 3.01Å; C39-H41 VanDerWaalsContact O-N 3.17Å; C39-F343 HydrophobicContact CB-CB 4.04Å; C39-F343 HydrophobicContact CB-CD1 4.1Å; C39-F343 HydrophobicContact CB-CG 4.45Å; C39-F343 CarbonylContact O-C 3.43Å; C39-F343 WeakPolarHBondContact O-CA 3.44Å; C39-N344 PolarHBondContact O-N 3.21Å; C39-V348 HydrophobicContact CB-CG2 4.46Å; C39-F349 WeakPolarHBondContact SG-CE2 3.33Å
40L98Very high96.7Very high47 Ų4769 Ų6925%0.24636%0.364CS..BIsolated β-bridgetrans-58.4120.1-173.5-173.861.9000111.7L36 E37 V38 R42 V45 H332 L335 V342 F343L36-L40 PolarHBondContact O-N 3.44Å; L36-L40 VanDerWaalsContact O-N 3.12Å; E37-L40 VanDerWaalsContact O-CB 3.31Å; E37-L40 WeakPolarHBondContact O-CB 3.46Å; E37-L40 PolarHBondContact O-N 3.38Å; V38-L40 PolarHBondContact O-N 3.32Å; L40-R42 PolarHBondContact O-N 3.16Å; L40-V45 HydrophobicContact CD1-CG2 3.65Å; L40-V45 HydrophobicContact CD2-CG2 4.08Å; L40-V45 HydrophobicContact CG-CG2 3.81Å; L40-H332 HydrophobicContact CD1-CB 4.49Å; L40-L335 HydrophobicContact CD2-CD1 4.22Å; L40-V342 HydrophobicContact CD1-CG2 3.82Å; L40-F343 HydrophobicContact CD1-CE1 4.28Å
41H98.1Very high96.7Very high66 Ų6673.7 Ų73.731%0.30639%0.386SS..  trans-83105.9-176-173.2-135.4000111.1C39 Q43 T44 V45 N341 V342C39-H41 PolarHBondContact O-N 3.01Å; C39-H41 VanDerWaalsContact O-N 3.17Å; H41-Q43 VanDerWaalsContact C-N 3.31Å; H41-Q43 PolarHBondContact O-N 3.15Å; H41-T44 PolarHBondContact ND1-OG1 3.14Å; H41-T44 PolarHBondContact O-N 3.32Å; H41-V45 PolarHBondContact O-N 2.98Å; H41-V45 VanDerWaalsContact O-N 3.11Å; H41-N341 WeakPolarHBondContact CB-O 3.46Å; H41-V342 PolarHBondContact N-O 3.03Å
42R97.9Very high96.7Very high175 Ų17570.1 Ų70.166%0.6636%0.362SS*.Hα-helixtrans-56.3-40.2-174179.858-176.3176.72113.7L40 V45 Q46L40-R42 PolarHBondContact O-N 3.16Å; R42-V45 PolarHBondContact O-N 2.91Å; R42-Q46 WeakPolarHBondContact O-CB 3.32Å; R42-Q46 PolarHBondContact O-N 3.22Å
43Q98.1Very high96.7Very high90 Ų9070.3 Ų70.342%0.42135%0.352SS..Hα-helixtrans-63.6-46.3179.9-172.263.346.700111H41 V45 Q46 D47H41-Q43 VanDerWaalsContact C-N 3.31Å; H41-Q43 PolarHBondContact O-N 3.15Å; Q43-V45 VanDerWaalsContact C-N 3.32Å; Q43-V45 PolarHBondContact O-N 2.83Å; Q43-Q46 PolarHBondContact O-N 3.28Å; Q43-Q46 VanDerWaalsContact O-N 3.12Å; Q43-D47 WeakPolarHBondContact CG-OD2 3.33Å; Q43-D47 PolarHBondContact NE2-OD1 3.47Å; Q43-D47 PolarHBondContact NE2-OD2 2.92Å; Q43-D47 VanDerWaalsContact O-CG 3.3Å; Q43-D47 PolarHBondContact O-N 3.38Å
44T97.8Very high96.7Very high15 Ų1568.6 Ų68.69%0.09234%0.342CS..Hα-helixtrans-57.3-45.7175.1-64.30000111.5H41 Q46 D47 T48 D339 N341H41-T44 PolarHBondContact ND1-OG1 3.14Å; H41-T44 PolarHBondContact O-N 3.32Å; T44-Q46 VanDerWaalsContact C-N 3.33Å; T44-Q46 PolarHBondContact O-N 3.18Å; T44-D47 PolarHBondContact O-N 3.17Å; T44-T48 WeakPolarHBondContact O-CB 3.48Å; T44-T48 PolarHBondContact O-N 3.07Å; T44-T48 VanDerWaalsContact O-N 3.12Å; T44-T48 PolarHBondContact O-OG1 2.97Å; T44-D339 HydrophobicContact CG2-CB 4.36Å; T44-D339 VanDerWaalsContact CG2-OD2 3.23Å; T44-D339 WeakPolarHBondContact CG2-OD2 3.26Å; T44-N341 PolarHBondContact OG1-O 3.49Å
45V97.7Very high96.8Very high27 Ų2768.1 Ų68.116%0.16435%0.346CS..Hα-helixtrans-61.8-41.4176.8175.10000111.9L40 H41 R42 Q43 T48 L335 I337L40-V45 HydrophobicContact CD1-CG2 3.65Å; L40-V45 HydrophobicContact CD2-CG2 4.08Å; L40-V45 HydrophobicContact CG-CG2 3.81Å; H41-V45 PolarHBondContact O-N 2.98Å; H41-V45 VanDerWaalsContact O-N 3.11Å; R42-V45 PolarHBondContact O-N 2.91Å; Q43-V45 VanDerWaalsContact C-N 3.32Å; Q43-V45 PolarHBondContact O-N 2.83Å; V45-T48 PolarHBondContact O-N 3.4Å; V45-L335 HydrophobicContact CG1-CD1 3.83Å; V45-L335 HydrophobicContact CG2-CD1 3.88Å; V45-I337 HydrophobicContact CG2-CD1 4.43Å
46Q97.8Very high97Very high117 Ų11765.7 Ų65.755%0.54733%0.33SS..Hα-helixtrans-66.9-38-178.9-175.2178.1-6500112.6R42 Q43 T44 T48R42-Q46 WeakPolarHBondContact O-CB 3.32Å; R42-Q46 PolarHBondContact O-N 3.22Å; Q43-Q46 PolarHBondContact O-N 3.28Å; Q43-Q46 VanDerWaalsContact O-N 3.12Å; T44-Q46 VanDerWaalsContact C-N 3.33Å; T44-Q46 PolarHBondContact O-N 3.18Å; Q46-T48 VanDerWaalsContact C-N 3.32Å
47D96.6Very high97.3Very high99 Ų9966 Ų6653%0.52934%0.337SS..Hα-helixtrans-84.2-11.5-177.6-61.9-21.4000112.7Q43 T44 V49Q43-D47 WeakPolarHBondContact CG-OD2 3.33Å; Q43-D47 PolarHBondContact NE2-OD1 3.47Å; Q43-D47 PolarHBondContact NE2-OD2 2.92Å; Q43-D47 VanDerWaalsContact O-CG 3.3Å; Q43-D47 PolarHBondContact O-N 3.38Å; T44-D47 PolarHBondContact O-N 3.17Å; D47-V49 PolarHBondContact O-N 2.83Å
48T96.4Very high97.1Very high30 Ų3066.1 Ų66.118%0.18434%0.342CS..  trans-72.6113.8-180-66.20000111T44 V45 Q46 I337 I407T44-T48 WeakPolarHBondContact O-CB 3.48Å; T44-T48 PolarHBondContact O-N 3.07Å; T44-T48 VanDerWaalsContact O-N 3.12Å; T44-T48 PolarHBondContact O-OG1 2.97Å; V45-T48 PolarHBondContact O-N 3.4Å; Q46-T48 VanDerWaalsContact C-N 3.32Å; T48-I337 HydrophobicContact CG2-CD1 3.84Å; T48-I337 HydrophobicContact CG2-CG1 3.99Å; T48-I407 HydrophobicContact CG2-CD1 4.07Å; T48-I407 HydrophobicContact CG2-CG2 3.5Å; T48-I407 VanDerWaalsContact CG2-CG2 3.5Å
49V95.4Very high96.9Very high77 Ų7766.9 Ų66.947%0.46734%0.343SS..  trans-123.9122177.2-178.50000110.5D47 I51 K389 I407D47-V49 PolarHBondContact O-N 2.83Å; V49-I51 HydrophobicContact CG1-CB 4.03Å; V49-I51 HydrophobicContact CG1-CG1 3.77Å; V49-I51 PolarHBondContact O-N 3.24Å; V49-K389 PolarHBondContact O-NZ 2.78Å; V49-I407 WeakPolarHBondContact O-CD1 3.36Å
50H96.3Very high96.8Very high34 Ų3466.9 Ų66.916%0.15734%0.344CS..  trans-80.351.9178.9-71-106.5000112.9F52 N402 I407H50-F52 HydrophobicContact CB-CE2 4.33Å; H50-N402 WeakPolarHBondContact CB-ND2 3.27Å; H50-I407 VanDerWaalsContact CE1-CG2 3.43Å; H50-I407 WeakPolarHBondContact CE1-CG2 3.4Å
51I96.6Very high96.8Very high124 Ų12470.1 Ų70.164%0.63636%0.356SS*.  trans-124.5137.8173.2-60.8-65.4000107.8V49 K389V49-I51 HydrophobicContact CG1-CB 4.03Å; V49-I51 HydrophobicContact CG1-CG1 3.77Å; V49-I51 PolarHBondContact O-N 3.24Å; I51-K389 WeakPolarHBondContact O-CE 3.47Å; I51-K389 PolarHBondContact O-NZ 3Å
52F98.1Very high96.8Very high31 Ų3169.3 Ų69.314%0.13636%0.356CS..  trans-132.7147.3-170.2-55.8-92000110.3H50 A377 T379 K389 W390 R391 I407H50-F52 HydrophobicContact CB-CE2 4.33Å; F52-A377 HydrophobicContact CB-CB 3.54Å; F52-A377 HydrophobicContact CD1-CB 4.35Å; F52-A377 HydrophobicContact CD2-CB 4.27Å; F52-A377 HydrophobicContact CG-CB 3.8Å; F52-T379 WeakPolarHBondContact CA-OG1 3.38Å; F52-K389 HydrophobicContact CD1-CD 4.32Å; F52-K389 HydrophobicContact CD1-CG 4.14Å; F52-K389 HydrophobicContact CE1-CB 4.41Å; F52-K389 HydrophobicContact CE1-CD 4.05Å; F52-K389 HydrophobicContact CE1-CG 4.04Å; F52-W390 WeakPolarHBondContact CE1-O 3.4Å; F52-R391 HydrophobicContact CD1-CB 3.94Å; F52-R391 HydrophobicContact CD2-CB 3.76Å; F52-R391 HydrophobicContact CD2-CG 4.05Å; F52-R391 HydrophobicContact CE1-CB 3.73Å; F52-R391 HydrophobicContact CE2-CB 3.53Å; F52-R391 HydrophobicContact CE2-CG 3.61Å; F52-R391 HydrophobicContact CG-CB 3.97Å; F52-R391 HydrophobicContact CZ-CB 3.51Å; F52-R391 HydrophobicContact CZ-CG 3.93Å; F52-I407 HydrophobicContact CE1-CD1 4.4Å; F52-I407 HydrophobicContact CE1-CG1 4.19Å; F52-I407 HydrophobicContact CZ-CB 4.21Å; F52-I407 HydrophobicContact CZ-CD1 4.24Å; F52-I407 HydrophobicContact CZ-CG1 4.05Å
53Q97.5Very high96.8Very high112 Ų11262.8 Ų62.852%0.52333%0.334SS..SBendtrans-75.4-44-174.8-175.7-175.7-4.400113.1V378 T379Q53-V378 PolarHBondContact N-O 3.24Å; Q53-T379 HydrophobicContact CB-CG2 4.13Å; Q53-T379 PolarHBondContact N-OG1 2.96Å
54H98.1Very high96.8Very high59 Ų5958.6 Ų58.627%0.27332%0.315SS..EExtended strand (participates in β ladder)trans-120.6119.6-179.3-60.4-74.3000109.1K316 A377 V378 D380H54-K316 HydrophobicContact CB-CG 4.17Å; H54-A377 CarbonylContact O-C 3.42Å; H54-A377 WeakPolarHBondContact O-CA 3.43Å; H54-A377 WeakPolarHBondContact O-CB 3.41Å; H54-V378 HydrophobicContact CB-CG1 4.08Å; H54-V378 PolarHBondContact N-O 3.39Å; H54-V378 PolarHBondContact O-N 2.78Å; H54-D380 IonicContact CD2-OD2 3.21Å; H54-D380 IonicContact NE2-OD2 3.44Å; H54-D380 PolarHBondContact NE2-OD2 3.28Å
55S98.1Very high96.9Very high80 Ų8059.8 Ų59.856%0.55932%0.32SS*.EExtended strand (participates in β ladder)trans-126.4150.7177.161.40000110.6T376S55-T376 WeakPolarHBondContact CA-O 3.38Å
56I97.9Very high96.9Very high6 Ų659 Ų593%0.03132%0.315CS..  trans-56.4154.6168.362.4177.2000110.9T58 L83 I315 A320 T376I56-T58 VanDerWaalsContact CD1-O 3.3Å; I56-T58 WeakPolarHBondContact CD1-O 3.23Å; I56-T58 PolarHBondContact O-N 2.87Å; I56-T58 VanDerWaalsContact O-N 3.15Å; I56-L83 HydrophobicContact CD1-CD1 3.73Å; I56-I315 HydrophobicContact CG2-CG2 4.37Å; I56-A320 HydrophobicContact CD1-CB 4.11Å; I56-T376 HydrophobicContact CD1-CG2 3.88Å; I56-T376 WeakPolarHBondContact CG1-O 3.37Å; I56-T376 PolarHBondContact N-O 3.37Å
57P95.2Very high96.9Very high90 Ų9058.2 Ų58.258%0.58431%0.31SS*.SBendtrans-62.4-25.9-174-26.634.3000115.1
58T91.9Very high97Very high71 Ų7159.8 Ų59.844%0.43632%0.318SS..  trans-153.7132.5-177.4-57.70000109.2I56I56-T58 VanDerWaalsContact CD1-O 3.3Å; I56-T58 WeakPolarHBondContact CD1-O 3.23Å; I56-T58 PolarHBondContact O-N 2.87Å; I56-T58 VanDerWaalsContact O-N 3.15Å
59E93.4Very high97.1Very high53 Ų5359 Ų5925%0.24831%0.314CS..  trans-90.7155170.2-58.3-163.512900111.1T376 R391 Y405E59-T376 WeakPolarHBondContact OE1-CB 3.44Å; E59-T376 PolarHBondContact OE1-OG1 3.13Å; E59-R391 WeakPolarHBondContact OE1-CD 3.47Å; E59-R391 IonicContact OE1-CZ 3.72Å; E59-R391 IonicContact OE1-NE 2.84Å; E59-R391 PolarHBondContact OE1-NE 3.13Å; E59-R391 IonicContact OE1-NH2 3.62Å; E59-R391 IonicContact OE2-CZ 3.74Å; E59-R391 IonicContact OE2-NE 2.76Å; E59-R391 PolarHBondContact OE2-NE 2.78Å; E59-R391 IonicContact OE2-NH2 3.56Å; E59-R391 PolarHBondContact OE2-NH2 2.68Å; E59-Y405 WeakPolarHBondContact CB-OH 3.39Å; E59-Y405 VanDerWaalsContact OE1-CE1 3.22Å; E59-Y405 WeakPolarHBondContact OE1-CE1 3.37Å
60G95.4Very high97.3Very high2 Ų256 Ų562%0.02130%0.298CS..  trans-73.1146.7-174.500000113.3
61K97.5Very high97.4Very high115 Ų11554.4 Ų54.450%0.529%0.291SS..SBendtrans-137141.1174.6-62.2-176.5-175.7-179.60111M86 E93 F94K61-M86 HydrophobicContact CB-CE 4.49Å; K61-E93 HydrophobicContact CB-CG 4.16Å; K61-E93 CarbonylContact O-C 3.48Å; K61-E93 VanDerWaalsContact O-CA 3.31Å; K61-E93 WeakPolarHBondContact O-CA 3.48Å; K61-F94 PolarHBondContact O-N 3.37Å
62P98.3Very high97.5Very high48 Ų4848.5 Ų48.531%0.31226%0.261SS..SBendcis-70.1172.6-9.432.2-37.9000112.4R82 E95P62-R82 PolarHBondContact O-NH1 3.17Å; P62-R82 PolarHBondContact O-NH2 2.86Å; P62-E95 HydrophobicContact CG-CG 4.32Å
63I98.3Very high97.5Very high39 Ų3947 Ų4720%0.225%0.254CS..PPolyproline II helixtrans-64.9135.1166.6-63.3-65.8000108.9E393 D398 Y405I63-E393 HydrophobicContact CD1-CG 4.36Å; I63-D398 HydrophobicContact CB-CB 4.23Å; I63-D398 HydrophobicContact CG1-CB 4.34Å; I63-D398 HydrophobicContact CG2-CB 4.44Å; I63-Y405 HydrophobicContact CD1-CD2 4.17Å; I63-Y405 HydrophobicContact CD1-CE2 3.37Å
64T98.8Very high97.6Very high1 Ų141.7 Ų41.71%0.00623%0.229CC..PPolyproline II helixtrans-90.5155.3-174.662.90000111.4N79 E95 S395 W396 G397T64-N79 WeakPolarHBondContact CG2-OD1 3.49Å; T64-N79 PolarHBondContact OG1-ND2 3.42Å; T64-N79 VanDerWaalsContact OG1-ND2 3.14Å; T64-N79 PolarHBondContact OG1-OD1 2.91Å; T64-E95 HydrophobicContact CG2-CG 4.14Å; T64-E95 VanDerWaalsContact CG2-OE1 3.32Å; T64-E95 WeakPolarHBondContact CG2-OE1 3.48Å; T64-S395 CarbonylContact O-C 3.52Å; T64-S395 WeakPolarHBondContact O-CA 3.39Å; T64-W396 PolarHBondContact O-N 2.9Å; T64-G397 PolarHBondContact O-N 2.83Å
65N98.7Very high97.6Very high40 Ų4038.9 Ų38.921%0.21422%0.216CC..BIsolated β-bridgetrans-141.2110.6-178.7-163.7-24000111K67 S395 W396N65-K67 PolarHBondContact ND2-NZ 2.65Å; N65-K67 PolarHBondContact O-N 3.12Å; N65-K67 WeakPolarHBondContact OD1-CD 3.35Å; N65-K67 PolarHBondContact OD1-N 3.42Å; N65-S395 CarbonylContact C-O 3.57Å; N65-S395 VanDerWaalsContact CA-O 3.27Å; N65-S395 WeakPolarHBondContact CA-O 3.47Å; N65-W396 VanDerWaalsContact CG-C 3.45Å; N65-W396 PolarHBondContact ND2-O 3.11Å
66Q98.4Very high97.6Very high11 Ų1135 Ų355%0.05119%0.19CC..  trans-76.3-11.8178.676.6-170.363.600113.6S69 R71 C72 F75 S395Q66-S69 PolarHBondContact NE2-O 3.42Å; Q66-S69 PolarHBondContact O-OG 2.83Å; Q66-R71 PolarHBondContact O-NH2 3.17Å; Q66-C72 VanDerWaalsContact OE1-CA 3.28Å; Q66-C72 VanDerWaalsContact OE1-CB 3.22Å; Q66-F75 VanDerWaalsContact CA-CZ 3.49Å; Q66-F75 HydrophobicContact CB-CD1 4.39Å; Q66-F75 HydrophobicContact CB-CD2 3.72Å; Q66-F75 HydrophobicContact CB-CE1 4.31Å; Q66-F75 HydrophobicContact CB-CE2 3.6Å; Q66-F75 HydrophobicContact CB-CG 4.12Å; Q66-F75 HydrophobicContact CB-CZ 3.93Å; Q66-S395 PolarHBondContact N-O 3.05Å; Q66-S395 PolarHBondContact OE1-OG 3.38Å
67K98.4Very high97.7Very high101 Ų10134.8 Ų34.844%0.43919%0.188SC..  trans53.3-137.2-177-59.6-68.3-173.8-1740111.6N65 S69 E171N65-K67 PolarHBondContact ND2-NZ 2.65Å; N65-K67 PolarHBondContact O-N 3.12Å; N65-K67 WeakPolarHBondContact OD1-CD 3.35Å; N65-K67 PolarHBondContact OD1-N 3.42Å; K67-S69 VanDerWaalsContact C-N 3.27Å; K67-S69 PolarHBondContact O-N 3.29Å; K67-S69 VanDerWaalsContact O-N 3.15Å; K67-E171 HydrophobicContact CB-CB 3.83Å; K67-E171 HydrophobicContact CB-CG 4.25Å; K67-E171 VanDerWaalsContact CB-O 3.3Å; K67-E171 WeakPolarHBondContact CB-O 3.11Å; K67-E171 HydrophobicContact CG-CB 4Å; K67-E171 HydrophobicContact CG-CG 3.98Å
68N98.4Very high97.8Very high132 Ų13230.6 Ų30.671%0.70616%0.161SC*.BIsolated β-bridgetrans-91.159-175.4-57.5-44.5000110.6E171 A172 S173N68-E171 CarbonylContact C-O 3.49Å; N68-E171 WeakPolarHBondContact CA-O 3.4Å; N68-E171 WeakPolarHBondContact CB-O 3.17Å; N68-E171 PolarHBondContact N-O 2.94Å; N68-A172 WeakPolarHBondContact O-CA 3.3Å; N68-S173 PolarHBondContact O-N 2.95Å
69S98.6Very high98.2Very high13 Ų1327.3 Ų27.39%0.09114%0.141CC..SBendtrans-142.9155.5176.170.30000110.8Q66 K67 R71 S170Q66-S69 PolarHBondContact NE2-O 3.42Å; Q66-S69 PolarHBondContact O-OG 2.83Å; K67-S69 VanDerWaalsContact C-N 3.27Å; K67-S69 PolarHBondContact O-N 3.29Å; K67-S69 VanDerWaalsContact O-N 3.15Å; S69-R71 PolarHBondContact O-N 3.28Å; S69-R71 PolarHBondContact OG-NE 2.83Å; S69-S170 WeakPolarHBondContact CB-O 3.2Å; S69-S170 PolarHBondContact OG-O 2.84Å
70G98.4Very high98.4Very high14 Ų1424.9 Ų24.914%0.14413%0.129CC..SBendtrans-85.930.8178.200000114C72 D142 A452G70-C72 VanDerWaalsContact C-N 3.31Å; G70-C72 PolarHBondContact O-N 3.25Å; G70-D142 PolarHBondContact N-OD2 3.11Å; G70-D142 CarbonylContact O-C 3.41Å; G70-A452 WeakPolarHBondContact O-CB 3.48Å
71R98.8Very high98.6Very high0 Ų024.8 Ų24.80%013%0.129CC..  trans-87.516.1-169.5-62.7-178.6-63.2155.4-1.6114.7Q66 S69 W73 I74 F75 F102 E166 S170Q66-R71 PolarHBondContact O-NH2 3.17Å; S69-R71 PolarHBondContact O-N 3.28Å; S69-R71 PolarHBondContact OG-NE 2.83Å; R71-W73 VanDerWaalsContact C-N 3.27Å; R71-W73 PolarHBondContact O-N 2.98Å; R71-I74 WeakPolarHBondContact O-CB 3.36Å; R71-I74 PolarHBondContact O-N 3.44Å; R71-F75 HydrophobicContact CB-CD2 3.83Å; R71-F75 HydrophobicContact CB-CE2 3.92Å; R71-F75 WeakPolarHBondContact O-CD2 3.18Å; R71-F75 PolarHBondContact O-N 2.86Å; R71-F102 VanDerWaalsContact CD-CG 3.41Å; R71-F102 HydrophobicContact CG-CD2 3.72Å; R71-F102 HydrophobicContact CG-CE2 3.97Å; R71-F102 HydrophobicContact CG-CG 4.12Å; R71-E166 IonicContact CZ-OE1 2.8Å; R71-E166 IonicContact CZ-OE2 3.79Å; R71-E166 VanDerWaalsContact CZ-OE2 3.23Å; R71-E166 VanDerWaalsContact NH1-CD 3.31Å; R71-E166 IonicContact NH1-OE1 3.12Å; R71-E166 PolarHBondContact NH1-OE1 3.31Å; R71-E166 IonicContact NH1-OE2 2.97Å; R71-E166 PolarHBondContact NH1-OE2 2.88Å; R71-E166 IonicContact NH2-OE1 2.64Å; R71-E166 IonicContact NH2-OE2 3.78Å; R71-E166 PolarHBondContact NH2-OE2 3.5Å; R71-S170 PolarHBondContact NE-O 3.03Å; R71-S170 VanDerWaalsContact NE-O 3.12Å; R71-S170 PolarHBondContact NH2-O 3.49Å
72C98.6Very high98.6Very high0 Ų019.4 Ų19.40%011%0.105CC..Hα-helixtrans-56.4-39.1-172.357.60000113.6Q66 G70 I74 F75 S76 H371 A372 L451 A452Q66-C72 VanDerWaalsContact OE1-CA 3.28Å; Q66-C72 VanDerWaalsContact OE1-CB 3.22Å; G70-C72 VanDerWaalsContact C-N 3.31Å; G70-C72 PolarHBondContact O-N 3.25Å; C72-I74 PolarHBondContact O-N 2.9Å; C72-F75 PolarHBondContact O-N 2.95Å; C72-S76 VanDerWaalsContact O-CB 3.25Å; C72-S76 WeakPolarHBondContact O-CB 3.35Å; C72-S76 PolarHBondContact O-N 3.33Å; C72-S76 PolarHBondContact O-OG 3.49Å; C72-H371 WeakPolarHBondContact CB-CE1 3.5Å; C72-H371 WeakPolarHBondContact CB-ND1 3.31Å; C72-H371 PolarHBondContact SG-ND1 2.91Å; C72-H371 VanDerWaalsContact SG-ND1 3.37Å; C72-A372 PolarHBondContact SG-N 2.82Å; C72-A372 VanDerWaalsContact SG-N 3.38Å; C72-L451 WeakPolarHBondContact SG-CD2 3.43Å; C72-A452 VanDerWaalsContact SG-CB 3.55Å
73W98.8Very high98.6Very high0 Ų018 Ų180%010%0.095CC..Hα-helixtrans-59.1-43.2175.262.3-67.6000113R71 C77 D105 D142 G144 M148 L149 L152 W322 A372 L451R71-W73 VanDerWaalsContact C-N 3.27Å; R71-W73 PolarHBondContact O-N 2.98Å; W73-C77 VanDerWaalsContact O-CB 3.3Å; W73-C77 WeakPolarHBondContact O-CB 3.47Å; W73-C77 PolarHBondContact O-N 3.43Å; W73-D105 HydrophobicContact CH2-CB 4.31Å; W73-D105 WeakPolarHBondContact CH2-OD1 3.26Å; W73-D105 HydrophobicContact CZ2-CB 4.38Å; W73-D142 PolarHBondContact NE1-O 2.74Å; W73-G144 VanDerWaalsContact CE3-C 3.49Å; W73-M148 HydrophobicContact CH2-CB 4.16Å; W73-M148 HydrophobicContact CZ3-CB 3.7Å; W73-L149 HydrophobicContact CD2-CD2 4.36Å; W73-L149 HydrophobicContact CE3-CD1 3.86Å; W73-L149 HydrophobicContact CE3-CD2 3.54Å; W73-L149 HydrophobicContact CE3-CG 3.4Å; W73-L149 HydrophobicContact CH2-CD2 4.45Å; W73-L149 HydrophobicContact CZ3-CB 4.49Å; W73-L149 HydrophobicContact CZ3-CD1 4.46Å; W73-L149 HydrophobicContact CZ3-CD2 3.58Å; W73-L149 HydrophobicContact CZ3-CG 3.52Å; W73-L152 HydrophobicContact CH2-CD1 3.95Å; W73-L152 HydrophobicContact CZ3-CD1 4.44Å; W73-W322 HydrophobicContact CB-CZ2 4.16Å; W73-W322 PolarHBondContact O-NE1 3.21Å; W73-A372 HydrophobicContact CB-CB 4.27Å; W73-L451 HydrophobicContact CB-CD1 4.37Å; W73-L451 HydrophobicContact CB-CD2 3.75Å; W73-L451 HydrophobicContact CG-CD2 4.3Å
74I98.9Very high98.6Very high0 Ų018.1 Ų18.10%010%0.098CC..Hα-helixtrans-64.8-49.4174.7-67.3167.8000110.5R71 C72 S76 C77 L78 Q98 L101 F102 L149R71-I74 WeakPolarHBondContact O-CB 3.36Å; R71-I74 PolarHBondContact O-N 3.44Å; C72-I74 PolarHBondContact O-N 2.9Å; I74-S76 PolarHBondContact O-N 3.41Å; I74-C77 PolarHBondContact O-N 2.83Å; I74-L78 HydrophobicContact CG2-CD1 3.86Å; I74-L78 HydrophobicContact CG2-CG 4.44Å; I74-L78 WeakPolarHBondContact O-CB 3.41Å; I74-L78 WeakPolarHBondContact O-CG 3.42Å; I74-L78 PolarHBondContact O-N 2.86Å; I74-Q98 HydrophobicContact CG2-CB 4.02Å; I74-Q98 HydrophobicContact CG2-CG 4.48Å; I74-L101 HydrophobicContact CD1-CB 4.4Å; I74-L101 HydrophobicContact CG2-CB 4.04Å; I74-L101 HydrophobicContact CG2-CD1 4.27Å; I74-F102 HydrophobicContact CD1-CB 4.14Å; I74-F102 HydrophobicContact CD1-CD2 4.43Å; I74-L149 HydrophobicContact CG1-CD2 3.98Å
75F98.9Very high98.6Very high0 Ų018.1 Ų18.10%010%0.098CC..Hα-helixtrans-59.8-47.7-179-87.4-102.8000111.4Q66 R71 C72 C77 L78 N79 Q98Q66-F75 VanDerWaalsContact CA-CZ 3.49Å; Q66-F75 HydrophobicContact CB-CD1 4.39Å; Q66-F75 HydrophobicContact CB-CD2 3.72Å; Q66-F75 HydrophobicContact CB-CE1 4.31Å; Q66-F75 HydrophobicContact CB-CE2 3.6Å; Q66-F75 HydrophobicContact CB-CG 4.12Å; Q66-F75 HydrophobicContact CB-CZ 3.93Å; R71-F75 HydrophobicContact CB-CD2 3.83Å; R71-F75 HydrophobicContact CB-CE2 3.92Å; R71-F75 WeakPolarHBondContact O-CD2 3.18Å; R71-F75 PolarHBondContact O-N 2.86Å; C72-F75 PolarHBondContact O-N 2.95Å; F75-C77 PolarHBondContact O-N 3.01Å; F75-L78 PolarHBondContact O-N 3.28Å; F75-N79 VanDerWaalsContact O-CB 3.3Å; F75-N79 WeakPolarHBondContact O-CB 3.46Å; F75-N79 PolarHBondContact O-N 2.85Å; F75-Q98 HydrophobicContact CD1-CG 3.84Å; F75-Q98 HydrophobicContact CD2-CB 3.94Å; F75-Q98 HydrophobicContact CD2-CG 3.83Å; F75-Q98 HydrophobicContact CE1-CB 4.3Å; F75-Q98 HydrophobicContact CE1-CG 3.67Å; F75-Q98 HydrophobicContact CE2-CB 3.48Å; F75-Q98 VanDerWaalsContact CE2-CB 3.48Å; F75-Q98 HydrophobicContact CE2-CG 3.67Å; F75-Q98 HydrophobicContact CG-CG 3.93Å; F75-Q98 HydrophobicContact CZ-CB 3.67Å; F75-Q98 HydrophobicContact CZ-CG 3.57Å
76S98.8Very high98.6Very high0 Ų016.6 Ų16.60%09%0.09CC..Hα-helixtrans-64-41.8179.8-64.60000111.5C72 I74 N79 V80 W322 A372 M373 I374C72-S76 VanDerWaalsContact O-CB 3.25Å; C72-S76 WeakPolarHBondContact O-CB 3.35Å; C72-S76 PolarHBondContact O-N 3.33Å; C72-S76 PolarHBondContact O-OG 3.49Å; I74-S76 PolarHBondContact O-N 3.41Å; S76-N79 PolarHBondContact O-N 3.08Å; S76-V80 PolarHBondContact O-N 2.77Å; S76-V80 VanDerWaalsContact O-N 3.1Å; S76-W322 VanDerWaalsContact CB-CD1 3.43Å; S76-A372 VanDerWaalsContact OG-C 3.22Å; S76-A372 PolarHBondContact OG-O 2.91Å; S76-M373 WeakPolarHBondContact OG-CA 3.19Å; S76-M373 PolarHBondContact OG-N 2.89Å; S76-I374 WeakPolarHBondContact O-CG2 3.18Å
77C98.8Very high98.6Very high0 Ų023.4 Ų23.40%012%0.119CC..Hα-helixtrans-59.9-52.1175.5-179.50000110.9W73 I74 F75 N79 V80 L81 W146 L149W73-C77 VanDerWaalsContact O-CB 3.3Å; W73-C77 WeakPolarHBondContact O-CB 3.47Å; W73-C77 PolarHBondContact O-N 3.43Å; I74-C77 PolarHBondContact O-N 2.83Å; F75-C77 PolarHBondContact O-N 3.01Å; C77-N79 VanDerWaalsContact C-N 3.26Å; C77-N79 PolarHBondContact O-N 3.11Å; C77-V80 PolarHBondContact O-N 2.8Å; C77-L81 WeakPolarHBondContact O-CD1 3.41Å; C77-L81 PolarHBondContact O-N 2.95Å; C77-W146 HydrophobicContact CB-CZ3 4.39Å; C77-L149 HydrophobicContact CB-CD1 3.5Å; C77-L149 HydrophobicContact CB-CD2 4.01Å; C77-L149 HydrophobicContact CB-CG 4.29Å
78L98.9Very high98.5Very high2 Ų225.4 Ų25.41%0.0113%0.128CC..Hα-helixtrans-66.6-27.7-179.4-66.1179.8000112.9I74 F75 L81 R82 F96 Q98 L101 V158I74-L78 HydrophobicContact CG2-CD1 3.86Å; I74-L78 HydrophobicContact CG2-CG 4.44Å; I74-L78 WeakPolarHBondContact O-CB 3.41Å; I74-L78 WeakPolarHBondContact O-CG 3.42Å; I74-L78 PolarHBondContact O-N 2.86Å; F75-L78 PolarHBondContact O-N 3.28Å; L78-L81 HydrophobicContact CD2-CD2 4.28Å; L78-R82 WeakPolarHBondContact O-CB 3.16Å; L78-R82 WeakPolarHBondContact O-CG 3.32Å; L78-R82 PolarHBondContact O-N 3.5Å; L78-F96 HydrophobicContact CB-CB 4.2Å; L78-F96 HydrophobicContact CB-CD2 4.38Å; L78-F96 HydrophobicContact CD1-CB 3.87Å; L78-F96 HydrophobicContact CD2-CB 3.73Å; L78-F96 HydrophobicContact CD2-CD2 3.96Å; L78-F96 HydrophobicContact CD2-CG 4.07Å; L78-F96 HydrophobicContact CG-CB 4.13Å; L78-Q98 HydrophobicContact CD1-CB 4.33Å; L78-Q98 HydrophobicContact CD1-CG 3.89Å; L78-L101 HydrophobicContact CD1-CD1 4.02Å; L78-L101 HydrophobicContact CD2-CD1 3.89Å; L78-L101 HydrophobicContact CG-CD1 4.12Å; L78-V158 HydrophobicContact CD2-CG1 3.95Å
79N98.9Very high98.5Very high2 Ų220.6 Ų20.61%0.01110%0.101CC..Hα-helixtrans-67.3-34.1171.2-79.6-9.2000112.2T64 F75 S76 C77 R82 L83 I374 E393T64-N79 WeakPolarHBondContact CG2-OD1 3.49Å; T64-N79 PolarHBondContact OG1-ND2 3.42Å; T64-N79 VanDerWaalsContact OG1-ND2 3.14Å; T64-N79 PolarHBondContact OG1-OD1 2.91Å; F75-N79 VanDerWaalsContact O-CB 3.3Å; F75-N79 WeakPolarHBondContact O-CB 3.46Å; F75-N79 PolarHBondContact O-N 2.85Å; S76-N79 PolarHBondContact O-N 3.08Å; C77-N79 VanDerWaalsContact C-N 3.26Å; C77-N79 PolarHBondContact O-N 3.11Å; N79-R82 WeakPolarHBondContact O-CG 3.31Å; N79-R82 PolarHBondContact OD1-NE 2.95Å; N79-R82 PolarHBondContact OD1-NH2 3.2Å; N79-L83 VanDerWaalsContact O-CG 3.3Å; N79-L83 WeakPolarHBondContact O-CG 3.21Å; N79-I374 HydrophobicContact CB-CD1 3.89Å; N79-I374 HydrophobicContact CB-CG1 4.46Å; N79-I374 HydrophobicContact CB-CG2 4.3Å; N79-E393 PolarHBondContact ND2-OE1 2.85Å
80V98.6Very high98.4Very high2 Ų222.5 Ų22.51%0.01211%0.111CC..Hα-helixtrans-70.8-51.4170.3-179.20000110.5S76 C77 R82 L83 P84 Y261 A320 W322 I374S76-V80 PolarHBondContact O-N 2.77Å; S76-V80 VanDerWaalsContact O-N 3.1Å; C77-V80 PolarHBondContact O-N 2.8Å; V80-R82 VanDerWaalsContact C-N 3.25Å; V80-R82 PolarHBondContact O-N 2.79Å; V80-L83 PolarHBondContact O-N 2.64Å; V80-P84 WeakPolarHBondContact O-CD 3.46Å; V80-Y261 HydrophobicContact CG1-CD2 4.24Å; V80-Y261 HydrophobicContact CG1-CE2 3.4Å; V80-A320 HydrophobicContact CG1-CB 4.45Å; V80-A320 WeakPolarHBondContact CG1-O 3.1Å; V80-A320 HydrophobicContact CG2-CB 4.26Å; V80-W322 HydrophobicContact CG2-CB 4.25Å; V80-I374 HydrophobicContact CG2-CB 4.13Å; V80-I374 HydrophobicContact CG2-CG2 3.47Å; V80-I374 VanDerWaalsContact CG2-CG2 3.47Å
81L98.3Very high98.4Very high1 Ų122.1 Ų22.11%0.00511%0.105CC..Hα-helixtrans-58.7-35.3-175.4-90.266.5000112.5C77 L78 L83 P84 F96 I153 V257 Y261C77-L81 WeakPolarHBondContact O-CD1 3.41Å; C77-L81 PolarHBondContact O-N 2.95Å; L78-L81 HydrophobicContact CD2-CD2 4.28Å; L81-L83 VanDerWaalsContact C-N 3.29Å; L81-L83 PolarHBondContact O-N 3.04Å; L81-P84 WeakPolarHBondContact O-CD 3.48Å; L81-F96 HydrophobicContact CB-CD2 4.18Å; L81-F96 HydrophobicContact CB-CE2 3.73Å; L81-I153 HydrophobicContact CD2-CD1 4.15Å; L81-V257 HydrophobicContact CD2-CG1 4.25Å; L81-Y261 HydrophobicContact CD1-CD1 3.44Å; L81-Y261 VanDerWaalsContact CD1-CD1 3.44Å; L81-Y261 HydrophobicContact CD1-CE1 3.32Å; L81-Y261 HydrophobicContact CD1-CG 4.29Å; L81-Y261 HydrophobicContact CG-CD1 3.68Å; L81-Y261 HydrophobicContact CG-CE1 4.12Å; L81-Y261 HydrophobicContact CG-CG 4.27Å
82R98.6Very high98.3Very high1 Ų128 Ų280%0.00413%0.132CC..Hα-helixtrans-69-25.7-175.768.4178.4179167.4-3.7113.3P62 L78 N79 V80 F85 M86 F94 F96 E393P62-R82 PolarHBondContact O-NH1 3.17Å; P62-R82 PolarHBondContact O-NH2 2.86Å; L78-R82 WeakPolarHBondContact O-CB 3.16Å; L78-R82 WeakPolarHBondContact O-CG 3.32Å; L78-R82 PolarHBondContact O-N 3.5Å; N79-R82 WeakPolarHBondContact O-CG 3.31Å; N79-R82 PolarHBondContact OD1-NE 2.95Å; N79-R82 PolarHBondContact OD1-NH2 3.2Å; V80-R82 VanDerWaalsContact C-N 3.25Å; V80-R82 PolarHBondContact O-N 2.79Å; R82-F85 PolarHBondContact O-N 2.86Å; R82-M86 HydrophobicContact CB-SD 4.31Å; R82-M86 HydrophobicContact CG-SD 4.18Å; R82-M86 VanDerWaalsContact O-CB 3.29Å; R82-M86 WeakPolarHBondContact O-CB 3.43Å; R82-M86 WeakPolarHBondContact O-CG 3.46Å; R82-M86 PolarHBondContact O-N 3.04Å; R82-F94 HydrophobicContact CB-CD1 4.04Å; R82-F94 WeakPolarHBondContact CD-O 3.4Å; R82-F94 PolarHBondContact NH1-O 2.97Å; R82-F96 HydrophobicContact CB-CD2 4.17Å; R82-F96 HydrophobicContact CB-CE2 4.04Å; R82-E393 IonicContact CZ-OE1 3.74Å; R82-E393 IonicContact NH2-OE1 3.67Å; R82-E393 PolarHBondContact NH2-OE1 3.19Å
83L98.6Very high98.3Very high18 Ų1834.2 Ų34.29%0.09416%0.162CC..Hα-helixtrans-63.7-56-172.7-55.7168.2000112.4I56 N79 V80 L81 F85 M86 K87 A320I56-L83 HydrophobicContact CD1-CD1 3.73Å; N79-L83 VanDerWaalsContact O-CG 3.3Å; N79-L83 WeakPolarHBondContact O-CG 3.21Å; V80-L83 PolarHBondContact O-N 2.64Å; L81-L83 VanDerWaalsContact C-N 3.29Å; L81-L83 PolarHBondContact O-N 3.04Å; L83-F85 VanDerWaalsContact C-N 3.27Å; L83-F85 PolarHBondContact O-N 2.87Å; L83-M86 PolarHBondContact O-N 2.97Å; L83-K87 PolarHBondContact O-N 3.48Å; L83-K87 VanDerWaalsContact O-N 3.12Å; L83-A320 HydrophobicContact CD1-CB 3.47Å; L83-A320 VanDerWaalsContact CD1-CB 3.47Å
84P98.3Very high98.3Very high42 Ų4234.8 Ų34.827%0.27316%0.164SC..Hα-helixtrans-66.8-30.7176.428.5-36.5000112.1V80 L81 K87 K88 L260V80-P84 WeakPolarHBondContact O-CD 3.46Å; L81-P84 WeakPolarHBondContact O-CD 3.48Å; P84-K87 PolarHBondContact O-N 3.12Å; P84-K88 WeakPolarHBondContact O-CB 3.36Å; P84-K88 PolarHBondContact O-N 2.84Å; P84-L260 HydrophobicContact CB-CB 4.17Å; P84-L260 HydrophobicContact CG-CB 4.48Å
85F98.4Very high98.3Very high1 Ų136.2 Ų36.20%0.00417%0.171CC..Hα-helixtrans-64.4-49175.8-174.7-94.9000112.3R82 L83 K87 K88 H89 L91 F94 F96 W232 F252 H256 V257 L260R82-F85 PolarHBondContact O-N 2.86Å; L83-F85 VanDerWaalsContact C-N 3.27Å; L83-F85 PolarHBondContact O-N 2.87Å; F85-K87 VanDerWaalsContact C-N 3.3Å; F85-K87 PolarHBondContact O-N 3.26Å; F85-K88 PolarHBondContact O-N 2.84Å; F85-H89 AromaticContact CD2-CD2 3.7Å; F85-H89 AromaticContact CE2-CD2 3.47Å; F85-H89 VanDerWaalsContact CE2-CD2 3.47Å; F85-H89 WeakPolarHBondContact CE2-CD2 3.48Å; F85-H89 AromaticContact CE2-NE2 3.58Å; F85-H89 AromaticContact CZ-CD2 3.67Å; F85-H89 PolarHBondContact O-CD2 2.99Å; F85-H89 PolarHBondContact O-N 2.76Å; F85-L91 HydrophobicContact CD1-CD1 4Å; F85-L91 HydrophobicContact CE1-CD1 3.8Å; F85-F94 AromaticContact CD1-CD1 3.83Å; F85-F94 HydrophobicContact CD1-CD1 3.83Å; F85-F94 HydrophobicContact CD1-CD2 4.45Å; F85-F94 AromaticContact CD1-CE1 3.58Å; F85-F94 HydrophobicContact CD1-CE1 3.58Å; F85-F94 HydrophobicContact CD1-CE2 4.22Å; F85-F94 HydrophobicContact CD1-CG 4.26Å; F85-F94 AromaticContact CD1-CZ 3.79Å; F85-F94 HydrophobicContact CD1-CZ 3.79Å; F85-F94 HydrophobicContact CE1-CD1 4.18Å; F85-F94 HydrophobicContact CE1-CD2 4.05Å; F85-F94 AromaticContact CE1-CE1 3.74Å; F85-F94 HydrophobicContact CE1-CE1 3.74Å; F85-F94 AromaticContact CE1-CE2 3.59Å; F85-F94 HydrophobicContact CE1-CE2 3.59Å; F85-F94 HydrophobicContact CE1-CG 4.33Å; F85-F94 AromaticContact CE1-CZ 3.42Å; F85-F94 HydrophobicContact CE1-CZ 3.42Å; F85-F94 VanDerWaalsContact CE1-CZ 3.42Å; F85-F94 HydrophobicContact CZ-CE2 4.47Å; F85-F94 HydrophobicContact CZ-CZ 4.23Å; F85-F96 HydrophobicContact CB-CZ 4.09Å; F85-F96 HydrophobicContact CD1-CE1 4.5Å; F85-F96 HydrophobicContact CD1-CZ 4.15Å; F85-F96 HydrophobicContact CD2-CZ 4.21Å; F85-F96 AromaticContact CG-CZ 3.89Å; F85-F96 HydrophobicContact CG-CZ 3.89Å; F85-W232 HydrophobicContact CE1-CH2 4.12Å; F85-W232 AromaticContact CE1-CZ3 3.95Å; F85-W232 HydrophobicContact CE1-CZ3 3.95Å; F85-W232 AromaticContact CZ-CZ3 3.92Å; F85-W232 HydrophobicContact CZ-CZ3 3.92Å; F85-F252 HydrophobicContact CE1-CZ 4.44Å; F85-F252 HydrophobicContact CE2-CE2 4.49Å; F85-F252 AromaticContact CE2-CZ 3.91Å; F85-F252 HydrophobicContact CE2-CZ 3.91Å; F85-F252 HydrophobicContact CZ-CE2 4.12Å; F85-F252 AromaticContact CZ-CZ 3.61Å; F85-F252 HydrophobicContact CZ-CZ 3.61Å; F85-H256 HydrophobicContact CE2-CB 4.06Å; F85-V257 HydrophobicContact CD2-CG2 3.93Å; F85-V257 HydrophobicContact CE2-CG2 4.09Å; F85-L260 HydrophobicContact CB-CD1 4.45Å; F85-L260 HydrophobicContact CD2-CD1 4.32Å
86M98.4Very high98.3Very high9 Ų936.3 Ų36.34%0.04417%0.171CC..Hα-helixtrans-58.6-43.1175.6-75.2173.771.800111.6K61 R82 L83 N90 L91 E92 F94K61-M86 HydrophobicContact CB-CE 4.49Å; R82-M86 HydrophobicContact CB-SD 4.31Å; R82-M86 HydrophobicContact CG-SD 4.18Å; R82-M86 VanDerWaalsContact O-CB 3.29Å; R82-M86 WeakPolarHBondContact O-CB 3.43Å; R82-M86 WeakPolarHBondContact O-CG 3.46Å; R82-M86 PolarHBondContact O-N 3.04Å; L83-M86 PolarHBondContact O-N 2.97Å; M86-N90 PolarHBondContact O-N 3.07Å; M86-N90 VanDerWaalsContact O-N 3.07Å; M86-L91 HydrophobicContact CB-CB 4.28Å; M86-L91 HydrophobicContact CG-CB 4.23Å; M86-L91 HydrophobicContact CG-CD1 4.44Å; M86-L91 PolarHBondContact O-N 2.88Å; M86-E92 VanDerWaalsContact CE-O 3.31Å; M86-E92 WeakPolarHBondContact CE-O 3.39Å; M86-F94 HydrophobicContact CG-CB 3.57Å; M86-F94 HydrophobicContact CG-CD1 4.35Å; M86-F94 HydrophobicContact CG-CG 4.32Å; M86-F94 HydrophobicContact SD-CB 4.02Å
87K97.6Very high98.3Very high153 Ų15336.3 Ų36.367%0.66517%0.171SC*.Hα-helixtrans-62.2-47.7175.9-175.4178.7178.9-179.10111.4L83 P84 F85 H89 N90L83-K87 PolarHBondContact O-N 3.48Å; L83-K87 VanDerWaalsContact O-N 3.12Å; P84-K87 PolarHBondContact O-N 3.12Å; F85-K87 VanDerWaalsContact C-N 3.3Å; F85-K87 PolarHBondContact O-N 3.26Å; K87-H89 PolarHBondContact O-N 2.87Å; K87-N90 PolarHBondContact O-N 3.46Å
88K97.6Very high98.3Very high144 Ų14436.4 Ų36.463%0.62617%0.172SC*.Hα-helixtrans-62-40.7-17917763.2176.6-1770112.7P84 F85 L260P84-K88 WeakPolarHBondContact O-CB 3.36Å; P84-K88 PolarHBondContact O-N 2.84Å; F85-K88 PolarHBondContact O-N 2.84Å; K88-L260 HydrophobicContact CB-CD1 3.59Å; K88-L260 HydrophobicContact CB-CD2 4.18Å; K88-L260 HydrophobicContact CD-CD2 4.23Å; K88-L260 HydrophobicContact CG-CD1 3.83Å; K88-L260 HydrophobicContact CG-CD2 4.03Å
89H97.1Very high98.3Very high31 Ų3136.3 Ų36.314%0.14417%0.171CC..THydrogen-bonded Turntrans-9710.5-175.3-70.4-77.9000113.9F85 K87 L91 Y234 M244F85-H89 AromaticContact CD2-CD2 3.7Å; F85-H89 AromaticContact CE2-CD2 3.47Å; F85-H89 VanDerWaalsContact CE2-CD2 3.47Å; F85-H89 WeakPolarHBondContact CE2-CD2 3.48Å; F85-H89 AromaticContact CE2-NE2 3.58Å; F85-H89 AromaticContact CZ-CD2 3.67Å; F85-H89 PolarHBondContact O-CD2 2.99Å; F85-H89 PolarHBondContact O-N 2.76Å; K87-H89 PolarHBondContact O-N 2.87Å; H89-L91 VanDerWaalsContact C-N 3.3Å; H89-L91 HydrophobicContact CB-CD1 3.96Å; H89-L91 HydrophobicContact CB-CD2 4.23Å; H89-L91 HydrophobicContact CB-CG 3.79Å; H89-L91 PolarHBondContact O-N 3.28Å; H89-Y234 PolarHBondContact ND1-OH 2.89Å; H89-M244 WeakPolarHBondContact CE1-CE 3.34Å
90N97.5Very high98.3Very high53 Ų5336.5 Ų36.528%0.28317%0.172SC..THydrogen-bonded Turntrans5146.7179.8-165.729000113M86 K87 D236 K237 D238M86-N90 PolarHBondContact O-N 3.07Å; M86-N90 VanDerWaalsContact O-N 3.07Å; K87-N90 PolarHBondContact O-N 3.46Å; N90-D236 HydrophobicContact CB-CB 4.22Å; N90-D236 WeakPolarHBondContact O-CA 3.39Å; N90-D236 WeakPolarHBondContact O-CB 3.42Å; N90-K237 WeakPolarHBondContact O-CG 3.15Å; N90-K237 PolarHBondContact O-N 2.65Å; N90-K237 WeakPolarHBondContact OD1-CD 3.05Å; N90-D238 PolarHBondContact ND2-OD2 3.23Å
91L98Very high98.3Very high6 Ų636.4 Ų36.43%0.03117%0.171CC..  trans-93.8136.7-176.2-56.2174.7000111.2F85 M86 H89 F94 W232 Y234 K237F85-L91 HydrophobicContact CD1-CD1 4Å; F85-L91 HydrophobicContact CE1-CD1 3.8Å; M86-L91 HydrophobicContact CB-CB 4.28Å; M86-L91 HydrophobicContact CG-CB 4.23Å; M86-L91 HydrophobicContact CG-CD1 4.44Å; M86-L91 PolarHBondContact O-N 2.88Å; H89-L91 VanDerWaalsContact C-N 3.3Å; H89-L91 HydrophobicContact CB-CD1 3.96Å; H89-L91 HydrophobicContact CB-CD2 4.23Å; H89-L91 HydrophobicContact CB-CG 3.79Å; H89-L91 PolarHBondContact O-N 3.28Å; L91-F94 HydrophobicContact CB-CB 4.45Å; L91-F94 HydrophobicContact CD1-CB 3.83Å; L91-F94 HydrophobicContact CD1-CD2 3.72Å; L91-F94 HydrophobicContact CD1-CE2 4.5Å; L91-F94 HydrophobicContact CD1-CG 3.83Å; L91-W232 HydrophobicContact CD1-CH2 3.69Å; L91-W232 HydrophobicContact CD2-CH2 4.06Å; L91-Y234 HydrophobicContact CD2-CD2 3.27Å; L91-Y234 HydrophobicContact CD2-CE2 3.38Å; L91-Y234 HydrophobicContact CD2-CG 4.07Å; L91-K237 VanDerWaalsContact C-CE 3.43Å; L91-K237 WeakPolarHBondContact O-CE 3.16Å
92E96.9Very high98.3Very high123 Ų12336.4 Ų36.458%0.57517%0.171SC*.SBendtrans-78.7-46170.7-171.6169.4-167.800111.7M86 K237M86-E92 VanDerWaalsContact CE-O 3.31Å; M86-E92 WeakPolarHBondContact CE-O 3.39Å; E92-K237 HydrophobicContact CB-CG 4.08Å
93E98.3Very high98.4Very high131 Ų13136.3 Ų36.361%0.61217%0.171SC*.SBendtrans-132.3134.8-179.4-68.6-177.6-177.500110.3K61K61-E93 HydrophobicContact CB-CG 4.16Å; K61-E93 CarbonylContact O-C 3.48Å; K61-E93 VanDerWaalsContact O-CA 3.31Å; K61-E93 WeakPolarHBondContact O-CA 3.48Å
94F98.7Very high98.4Very high11 Ų1137.6 Ų37.65%0.04817%0.174CC..  trans-159.5144.7176-176.4-97.3000112.1K61 R82 F85 M86 L91 F96 P160 W232K61-F94 PolarHBondContact O-N 3.37Å; R82-F94 HydrophobicContact CB-CD1 4.04Å; R82-F94 WeakPolarHBondContact CD-O 3.4Å; R82-F94 PolarHBondContact NH1-O 2.97Å; F85-F94 AromaticContact CD1-CD1 3.83Å; F85-F94 HydrophobicContact CD1-CD1 3.83Å; F85-F94 HydrophobicContact CD1-CD2 4.45Å; F85-F94 AromaticContact CD1-CE1 3.58Å; F85-F94 HydrophobicContact CD1-CE1 3.58Å; F85-F94 HydrophobicContact CD1-CE2 4.22Å; F85-F94 HydrophobicContact CD1-CG 4.26Å; F85-F94 AromaticContact CD1-CZ 3.79Å; F85-F94 HydrophobicContact CD1-CZ 3.79Å; F85-F94 HydrophobicContact CE1-CD1 4.18Å; F85-F94 HydrophobicContact CE1-CD2 4.05Å; F85-F94 AromaticContact CE1-CE1 3.74Å; F85-F94 HydrophobicContact CE1-CE1 3.74Å; F85-F94 AromaticContact CE1-CE2 3.59Å; F85-F94 HydrophobicContact CE1-CE2 3.59Å; F85-F94 HydrophobicContact CE1-CG 4.33Å; F85-F94 AromaticContact CE1-CZ 3.42Å; F85-F94 HydrophobicContact CE1-CZ 3.42Å; F85-F94 VanDerWaalsContact CE1-CZ 3.42Å; F85-F94 HydrophobicContact CZ-CE2 4.47Å; F85-F94 HydrophobicContact CZ-CZ 4.23Å; M86-F94 HydrophobicContact CG-CB 3.57Å; M86-F94 HydrophobicContact CG-CD1 4.35Å; M86-F94 HydrophobicContact CG-CG 4.32Å; M86-F94 HydrophobicContact SD-CB 4.02Å; L91-F94 HydrophobicContact CB-CB 4.45Å; L91-F94 HydrophobicContact CD1-CB 3.83Å; L91-F94 HydrophobicContact CD1-CD2 3.72Å; L91-F94 HydrophobicContact CD1-CE2 4.5Å; L91-F94 HydrophobicContact CD1-CG 3.83Å; F94-F96 AromaticContact CE1-CD1 3.51Å; F94-F96 HydrophobicContact CE1-CD1 3.51Å; F94-F96 AromaticContact CE1-CD2 3.92Å; F94-F96 HydrophobicContact CE1-CD2 3.92Å; F94-F96 AromaticContact CE1-CE1 3.41Å; F94-F96 HydrophobicContact CE1-CE1 3.41Å; F94-F96 VanDerWaalsContact CE1-CE1 3.41Å; F94-F96 AromaticContact CE1-CE2 3.87Å; F94-F96 HydrophobicContact CE1-CE2 3.87Å; F94-F96 AromaticContact CE1-CG 3.75Å; F94-F96 HydrophobicContact CE1-CG 3.75Å; F94-F96 AromaticContact CE1-CZ 3.63Å; F94-F96 HydrophobicContact CE1-CZ 3.63Å; F94-F96 AromaticContact CZ-CD1 3.61Å; F94-F96 HydrophobicContact CZ-CD1 3.61Å; F94-F96 AromaticContact CZ-CE1 3.53Å; F94-F96 HydrophobicContact CZ-CE1 3.53Å; F94-F96 HydrophobicContact CZ-CG 4.26Å; F94-F96 HydrophobicContact CZ-CZ 4.17Å; F94-P160 HydrophobicContact CE2-CB 3.87Å; F94-P160 HydrophobicContact CE2-CG 4.07Å; F94-P160 HydrophobicContact CZ-CB 4.21Å; F94-P160 HydrophobicContact CZ-CG 4.25Å; F94-W232 AromaticContact CD2-CH2 3.62Å; F94-W232 HydrophobicContact CD2-CH2 3.62Å; F94-W232 AromaticContact CD2-CZ2 3.6Å; F94-W232 HydrophobicContact CD2-CZ2 3.6Å; F94-W232 AromaticContact CE2-CH2 3.51Å; F94-W232 HydrophobicContact CE2-CH2 3.51Å; F94-W232 AromaticContact CE2-CZ2 3.58Å; F94-W232 HydrophobicContact CE2-CZ2 3.58Å; F94-W232 HydrophobicContact CE2-CZ3 4.03Å
95E98.9Very high98.4Very high30 Ų3035.6 Ų35.614%0.1416%0.161CC..  trans-136.9139.7167.1-68.2-176.878.500109P62 T64 Q98 K161P62-E95 HydrophobicContact CG-CG 4.32Å; T64-E95 HydrophobicContact CG2-CG 4.14Å; T64-E95 VanDerWaalsContact CG2-OE1 3.32Å; T64-E95 WeakPolarHBondContact CG2-OE1 3.48Å; E95-Q98 PolarHBondContact OE1-NE2 3.41Å; E95-K161 HydrophobicContact CB-CB 3.84Å; E95-K161 HydrophobicContact CB-CD 3.67Å; E95-K161 HydrophobicContact CB-CG 4.43Å; E95-K161 VanDerWaalsContact CD-CD 3.5Å; E95-K161 HydrophobicContact CG-CD 4.22Å; E95-K161 WeakPolarHBondContact O-CB 3.47Å; E95-K161 PolarHBondContact O-N 2.84Å; E95-K161 IonicContact OE1-NZ 2.85Å; E95-K161 PolarHBondContact OE1-NZ 2.92Å; E95-K161 WeakPolarHBondContact OE2-CD 3.49Å; E95-K161 IonicContact OE2-NZ 3.64Å; E95-K161 PolarHBondContact OE2-NZ 3.43Å
96F98.9Very high98.4Very high2 Ų235.5 Ų35.51%0.00916%0.161CC..BIsolated β-bridgetrans-74.1153.6157.9-66.5-64.1000109.7L78 L81 R82 F85 F94 Q98 V158 I159 F252 V257L78-F96 HydrophobicContact CB-CB 4.2Å; L78-F96 HydrophobicContact CB-CD2 4.38Å; L78-F96 HydrophobicContact CD1-CB 3.87Å; L78-F96 HydrophobicContact CD2-CB 3.73Å; L78-F96 HydrophobicContact CD2-CD2 3.96Å; L78-F96 HydrophobicContact CD2-CG 4.07Å; L78-F96 HydrophobicContact CG-CB 4.13Å; L81-F96 HydrophobicContact CB-CD2 4.18Å; L81-F96 HydrophobicContact CB-CE2 3.73Å; R82-F96 HydrophobicContact CB-CD2 4.17Å; R82-F96 HydrophobicContact CB-CE2 4.04Å; F85-F96 HydrophobicContact CB-CZ 4.09Å; F85-F96 HydrophobicContact CD1-CE1 4.5Å; F85-F96 HydrophobicContact CD1-CZ 4.15Å; F85-F96 HydrophobicContact CD2-CZ 4.21Å; F85-F96 AromaticContact CG-CZ 3.89Å; F85-F96 HydrophobicContact CG-CZ 3.89Å; F94-F96 AromaticContact CE1-CD1 3.51Å; F94-F96 HydrophobicContact CE1-CD1 3.51Å; F94-F96 AromaticContact CE1-CD2 3.92Å; F94-F96 HydrophobicContact CE1-CD2 3.92Å; F94-F96 AromaticContact CE1-CE1 3.41Å; F94-F96 HydrophobicContact CE1-CE1 3.41Å; F94-F96 VanDerWaalsContact CE1-CE1 3.41Å; F94-F96 AromaticContact CE1-CE2 3.87Å; F94-F96 HydrophobicContact CE1-CE2 3.87Å; F94-F96 AromaticContact CE1-CG 3.75Å; F94-F96 HydrophobicContact CE1-CG 3.75Å; F94-F96 AromaticContact CE1-CZ 3.63Å; F94-F96 HydrophobicContact CE1-CZ 3.63Å; F94-F96 AromaticContact CZ-CD1 3.61Å; F94-F96 HydrophobicContact CZ-CD1 3.61Å; F94-F96 AromaticContact CZ-CE1 3.53Å; F94-F96 HydrophobicContact CZ-CE1 3.53Å; F94-F96 HydrophobicContact CZ-CG 4.26Å; F94-F96 HydrophobicContact CZ-CZ 4.17Å; F96-Q98 VanDerWaalsContact O-CD 3.26Å; F96-Q98 PolarHBondContact O-N 3.36Å; F96-Q98 VanDerWaalsContact O-N 3.17Å; F96-Q98 PolarHBondContact O-OE1 3.44Å; F96-V158 HydrophobicContact CD1-CB 4.11Å; F96-V158 HydrophobicContact CD1-CG2 3.95Å; F96-V158 HydrophobicContact CE1-CG2 3.89Å; F96-V158 HydrophobicContact CG-CB 4.49Å; F96-V158 HydrophobicContact CZ-CG2 4.43Å; F96-I159 CarbonylContact C-O 3.17Å; F96-I159 VanDerWaalsContact CA-O 3.3Å; F96-I159 WeakPolarHBondContact CA-O 3.35Å; F96-F252 HydrophobicContact CD1-CE1 4.25Å; F96-F252 AromaticContact CE1-CE1 3.69Å; F96-F252 HydrophobicContact CE1-CE1 3.69Å; F96-F252 HydrophobicContact CE1-CZ 4.1Å; F96-V257 HydrophobicContact CE1-CG2 3.94Å; F96-V257 HydrophobicContact CZ-CG1 4.24Å; F96-V257 HydrophobicContact CZ-CG2 3.84Å
97S98.9Very high98.4Very high1 Ų135.7 Ų35.71%0.00716%0.162CC..  trans-70.1108.9176.8178.60000110.6S99 Y100 I159 F164S97-S99 PolarHBondContact OG-OG 3.21Å; S97-Y100 VanDerWaalsContact OG-CB 3.27Å; S97-Y100 WeakPolarHBondContact OG-CB 3.35Å; S97-Y100 PolarHBondContact OG-N 3.31Å; S97-I159 PolarHBondContact N-O 3.37Å; S97-F164 WeakPolarHBondContact CB-O 3.44Å; S97-F164 PolarHBondContact OG-O 3.36Å
98Q98.9Very high98.5Very high1 Ų128.9 Ų28.91%0.00513%0.133CC..Hα-helixtrans-72-36173.2-53.990.6-13.200111I74 F75 L78 E95 F96 Y100 L101 F102I74-Q98 HydrophobicContact CG2-CB 4.02Å; I74-Q98 HydrophobicContact CG2-CG 4.48Å; F75-Q98 HydrophobicContact CD1-CG 3.84Å; F75-Q98 HydrophobicContact CD2-CB 3.94Å; F75-Q98 HydrophobicContact CD2-CG 3.83Å; F75-Q98 HydrophobicContact CE1-CB 4.3Å; F75-Q98 HydrophobicContact CE1-CG 3.67Å; F75-Q98 HydrophobicContact CE2-CB 3.48Å; F75-Q98 VanDerWaalsContact CE2-CB 3.48Å; F75-Q98 HydrophobicContact CE2-CG 3.67Å; F75-Q98 HydrophobicContact CG-CG 3.93Å; F75-Q98 HydrophobicContact CZ-CB 3.67Å; F75-Q98 HydrophobicContact CZ-CG 3.57Å; L78-Q98 HydrophobicContact CD1-CB 4.33Å; L78-Q98 HydrophobicContact CD1-CG 3.89Å; E95-Q98 PolarHBondContact OE1-NE2 3.41Å; F96-Q98 VanDerWaalsContact O-CD 3.26Å; F96-Q98 PolarHBondContact O-N 3.36Å; F96-Q98 VanDerWaalsContact O-N 3.17Å; F96-Q98 PolarHBondContact O-OE1 3.44Å; Q98-Y100 VanDerWaalsContact C-N 3.27Å; Q98-Y100 PolarHBondContact O-N 3.44Å; Q98-L101 PolarHBondContact O-N 3.12Å; Q98-F102 WeakPolarHBondContact O-CB 3.24Å; Q98-F102 PolarHBondContact O-N 2.99Å
99S98.9Very high98.6Very high0 Ų023.1 Ų23.10%011%0.107CC..Hα-helixtrans-62-31174.155.50000113S97 F102 F103 F164 P165 E166S97-S99 PolarHBondContact OG-OG 3.21Å; S99-F102 PolarHBondContact O-N 2.78Å; S99-F103 WeakPolarHBondContact O-CB 3.23Å; S99-F103 PolarHBondContact O-N 3.14Å; S99-F164 VanDerWaalsContact OG-CD1 3.3Å; S99-F164 WeakPolarHBondContact OG-CD1 3.42Å; S99-F164 PolarHBondContact OG-O 2.73Å; S99-P165 PolarHBondContact OG-O 3.48Å; S99-E166 WeakPolarHBondContact CB-OE1 3.15Å; S99-E166 PolarHBondContact N-OE1 3.39Å
100Y98.9Very high98.6Very high6 Ų621.6 Ų21.62%0.02410%0.1CC..Hα-helixtrans-65.2-49.7177.4176.7-99000112.1S97 Q98 F102 F103 W104 Y156 I159 P226 P249S97-Y100 VanDerWaalsContact OG-CB 3.27Å; S97-Y100 WeakPolarHBondContact OG-CB 3.35Å; S97-Y100 PolarHBondContact OG-N 3.31Å; Q98-Y100 VanDerWaalsContact C-N 3.27Å; Q98-Y100 PolarHBondContact O-N 3.44Å; Y100-F102 VanDerWaalsContact C-N 3.31Å; Y100-F102 PolarHBondContact O-N 2.99Å; Y100-F103 PolarHBondContact O-N 3.47Å; Y100-W104 AromaticContact CE1-CD1 3.78Å; Y100-W104 AromaticContact CE1-NE1 3.93Å; Y100-W104 AromaticContact CE2-CD1 3.87Å; Y100-W104 AromaticContact CE2-NE1 3.33Å; Y100-W104 VanDerWaalsContact CE2-NE1 3.33Å; Y100-W104 AromaticContact CZ-CD1 3.59Å; Y100-W104 AromaticContact CZ-NE1 3.24Å; Y100-W104 PolarHBondContact O-N 3.39Å; Y100-W104 PolarHBondContact OH-NE1 2.53Å; Y100-Y156 WeakPolarHBondContact CE1-O 3.47Å; Y100-Y156 PolarHBondContact OH-O 2.88Å; Y100-I159 HydrophobicContact CD1-CD1 4.48Å; Y100-I159 HydrophobicContact CD1-CG1 4.15Å; Y100-I159 HydrophobicContact CD2-CD1 3.38Å; Y100-I159 HydrophobicContact CD2-CG1 3.94Å; Y100-I159 HydrophobicContact CE2-CD1 3.94Å; Y100-I159 HydrophobicContact CG-CD1 3.7Å; Y100-I159 HydrophobicContact CG-CG1 3.74Å; Y100-P226 HydrophobicContact CD2-CB 3.97Å; Y100-P226 HydrophobicContact CE2-CB 3.76Å; Y100-P249 HydrophobicContact CE1-CB 4.32Å; Y100-P249 HydrophobicContact CE2-CB 4.39Å; Y100-P249 HydrophobicContact CE2-CG 4.14Å; Y100-P249 WeakPolarHBondContact OH-CB 3.49Å; Y100-P249 WeakPolarHBondContact OH-CG 3Å
101L98.9Very high98.7Very high1 Ų122 Ų221%0.00510%0.098CC..Hα-helixtrans-67.1-35.9175.5-66.9-172000111.4I74 L78 Q98 F103 W104 D105 L152 I153 G157 V158I74-L101 HydrophobicContact CD1-CB 4.4Å; I74-L101 HydrophobicContact CG2-CB 4.04Å; I74-L101 HydrophobicContact CG2-CD1 4.27Å; L78-L101 HydrophobicContact CD1-CD1 4.02Å; L78-L101 HydrophobicContact CD2-CD1 3.89Å; L78-L101 HydrophobicContact CG-CD1 4.12Å; Q98-L101 PolarHBondContact O-N 3.12Å; L101-F103 VanDerWaalsContact C-N 3.34Å; L101-F103 PolarHBondContact O-N 3.28Å; L101-W104 PolarHBondContact O-N 3.2Å; L101-D105 WeakPolarHBondContact O-CB 3.24Å; L101-D105 PolarHBondContact O-N 2.94Å; L101-L152 HydrophobicContact CD2-CB 4.31Å; L101-I153 HydrophobicContact CD1-CD1 4.02Å; L101-I153 HydrophobicContact CD1-CG1 3.91Å; L101-I153 HydrophobicContact CD2-CG1 4.07Å; L101-G157 WeakPolarHBondContact CD2-O 3.49Å; L101-V158 HydrophobicContact CD1-CG1 4.38Å; L101-V158 HydrophobicContact CD2-CG1 4.43Å
102F98.9Very high98.7Very high0 Ų024.4 Ų24.40%011%0.107CC..Hα-helixtrans-63.1-39.1176.3-177.2-125.3000112.9R71 I74 Q98 S99 Y100 K106 D142 M176 L223R71-F102 VanDerWaalsContact CD-CG 3.41Å; R71-F102 HydrophobicContact CG-CD2 3.72Å; R71-F102 HydrophobicContact CG-CE2 3.97Å; R71-F102 HydrophobicContact CG-CG 4.12Å; I74-F102 HydrophobicContact CD1-CB 4.14Å; I74-F102 HydrophobicContact CD1-CD2 4.43Å; Q98-F102 WeakPolarHBondContact O-CB 3.24Å; Q98-F102 PolarHBondContact O-N 2.99Å; S99-F102 PolarHBondContact O-N 2.78Å; Y100-F102 VanDerWaalsContact C-N 3.31Å; Y100-F102 PolarHBondContact O-N 2.99Å; F102-K106 WeakPolarHBondContact O-CB 3.37Å; F102-K106 PolarHBondContact O-N 3.45Å; F102-D142 HydrophobicContact CE2-CB 4.1Å; F102-D142 VanDerWaalsContact CE2-OD1 3.25Å; F102-D142 WeakPolarHBondContact CE2-OD1 3.2Å; F102-D142 VanDerWaalsContact CZ-OD1 3.29Å; F102-D142 WeakPolarHBondContact CZ-OD1 3.27Å; F102-M176 HydrophobicContact CE1-CE 3.6Å; F102-M176 HydrophobicContact CZ-CE 3.69Å; F102-L223 HydrophobicContact CD1-CD1 4.06Å; F102-L223 HydrophobicContact CD1-CD2 4.11Å; F102-L223 HydrophobicContact CE1-CD1 4.31Å; F102-L223 HydrophobicContact CE1-CD2 4.11Å
103F98.9Very high98.8Very high0 Ų019 Ų190%08%0.082CC..Hα-helixtrans-57.9-54.7173.7178.2-82.6000110.7S99 Y100 L101 D105 K106 I107 F216 A219 L223 G224 P226S99-F103 WeakPolarHBondContact O-CB 3.23Å; S99-F103 PolarHBondContact O-N 3.14Å; Y100-F103 PolarHBondContact O-N 3.47Å; L101-F103 VanDerWaalsContact C-N 3.34Å; L101-F103 PolarHBondContact O-N 3.28Å; F103-D105 PolarHBondContact O-N 3.11Å; F103-K106 PolarHBondContact O-N 2.85Å; F103-I107 HydrophobicContact CD1-CG1 4.39Å; F103-I107 HydrophobicContact CE1-CG1 3.97Å; F103-I107 HydrophobicContact CZ-CG1 4.25Å; F103-I107 PolarHBondContact O-N 3.25Å; F103-F216 AromaticContact CE1-CE2 3.93Å; F103-F216 HydrophobicContact CE1-CE2 3.93Å; F103-F216 HydrophobicContact CE1-CZ 4.17Å; F103-F216 HydrophobicContact CZ-CD2 4.32Å; F103-F216 HydrophobicContact CZ-CE1 4.27Å; F103-F216 AromaticContact CZ-CE2 3.78Å; F103-F216 HydrophobicContact CZ-CE2 3.78Å; F103-F216 AromaticContact CZ-CZ 3.76Å; F103-F216 HydrophobicContact CZ-CZ 3.76Å; F103-A219 HydrophobicContact CD2-CB 4.35Å; F103-A219 HydrophobicContact CE2-CB 4Å; F103-L223 HydrophobicContact CB-CD1 4.12Å; F103-L223 HydrophobicContact CD2-CB 4.07Å; F103-L223 HydrophobicContact CD2-CD1 4.02Å; F103-G224 WeakPolarHBondContact CE2-O 3.14Å; F103-P226 HydrophobicContact CB-CG 4.34Å; F103-P226 HydrophobicContact CD1-CG 3.23Å; F103-P226 HydrophobicContact CD2-CG 4.09Å; F103-P226 HydrophobicContact CE1-CG 3.41Å; F103-P226 VanDerWaalsContact CE1-CG 3.41Å; F103-P226 HydrophobicContact CE2-CG 4.23Å; F103-P226 HydrophobicContact CG-CG 3.62Å; F103-P226 HydrophobicContact CZ-CG 3.92Å
104W98.9Very high98.9Very high44 Ų4412.8 Ų12.817%0.1675%0.053CC..Hα-helixtrans-66.9-37.7-177-72.1121000112.8Y100 L101 K106 I107 E108 L152 Y156 F216 P226Y100-W104 AromaticContact CE1-CD1 3.78Å; Y100-W104 AromaticContact CE1-NE1 3.93Å; Y100-W104 AromaticContact CE2-CD1 3.87Å; Y100-W104 AromaticContact CE2-NE1 3.33Å; Y100-W104 VanDerWaalsContact CE2-NE1 3.33Å; Y100-W104 AromaticContact CZ-CD1 3.59Å; Y100-W104 AromaticContact CZ-NE1 3.24Å; Y100-W104 PolarHBondContact O-N 3.39Å; Y100-W104 PolarHBondContact OH-NE1 2.53Å; L101-W104 PolarHBondContact O-N 3.2Å; W104-K106 VanDerWaalsContact C-N 3.32Å; W104-K106 PolarHBondContact O-N 3.12Å; W104-I107 PolarHBondContact O-N 3.43Å; W104-E108 WeakPolarHBondContact O-CB 3.05Å; W104-E108 WeakPolarHBondContact O-CG 3.42Å; W104-E108 PolarHBondContact O-N 3.22Å; W104-L152 HydrophobicContact CB-CD2 3.93Å; W104-Y156 HydrophobicContact CB-CD2 3.74Å; W104-Y156 HydrophobicContact CB-CE2 3.96Å; W104-Y156 HydrophobicContact CB-CG 4.09Å; W104-Y156 AromaticContact CD1-CD1 3.95Å; W104-Y156 AromaticContact CD1-CG 3.69Å; W104-Y156 AromaticContact CD2-CD1 3.43Å; W104-Y156 HydrophobicContact CD2-CD1 3.43Å; W104-Y156 VanDerWaalsContact CD2-CD1 3.43Å; W104-Y156 HydrophobicContact CD2-CD2 4.09Å; W104-Y156 AromaticContact CD2-CE1 3.42Å; W104-Y156 HydrophobicContact CD2-CE1 3.42Å; W104-Y156 VanDerWaalsContact CD2-CE1 3.42Å; W104-Y156 HydrophobicContact CD2-CE2 4.08Å; W104-Y156 AromaticContact CD2-CG 3.76Å; W104-Y156 HydrophobicContact CD2-CG 3.76Å; W104-Y156 AromaticContact CD2-CZ 3.74Å; W104-Y156 AromaticContact CE2-CD1 3.39Å; W104-Y156 AromaticContact CE2-CE1 3.67Å; W104-Y156 AromaticContact CE2-CG 3.98Å; W104-Y156 AromaticContact CE3-CD1 3.87Å; W104-Y156 HydrophobicContact CE3-CD1 3.87Å; W104-Y156 AromaticContact CE3-CE1 3.31Å; W104-Y156 HydrophobicContact CE3-CE1 3.31Å; W104-Y156 HydrophobicContact CE3-CE2 4.05Å; W104-Y156 HydrophobicContact CE3-CG 4.43Å; W104-Y156 AromaticContact CE3-CZ 3.39Å; W104-Y156 AromaticContact CG-CD1 3.8Å; W104-Y156 HydrophobicContact CG-CD1 3.8Å; W104-Y156 AromaticContact CG-CD2 3.74Å; W104-Y156 HydrophobicContact CG-CD2 3.74Å; W104-Y156 HydrophobicContact CG-CE1 4.12Å; W104-Y156 HydrophobicContact CG-CE2 4.07Å; W104-Y156 AromaticContact CG-CG 3.58Å; W104-Y156 HydrophobicContact CG-CG 3.58Å; W104-Y156 HydrophobicContact CH2-CD1 4.23Å; W104-Y156 AromaticContact CH2-CE1 3.77Å; W104-Y156 HydrophobicContact CH2-CE1 3.77Å; W104-Y156 AromaticContact CZ2-CD1 3.82Å; W104-Y156 HydrophobicContact CZ2-CD1 3.82Å; W104-Y156 AromaticContact CZ2-CE1 3.85Å; W104-Y156 HydrophobicContact CZ2-CE1 3.85Å; W104-Y156 HydrophobicContact CZ3-CD1 4.25Å; W104-Y156 AromaticContact CZ3-CE1 3.5Å; W104-Y156 HydrophobicContact CZ3-CE1 3.5Å; W104-Y156 AromaticContact CZ3-CZ 3.87Å; W104-Y156 AromaticContact NE1-CD1 3.69Å; W104-Y156 AromaticContact NE1-CG 3.89Å; W104-F216 HydrophobicContact CZ3-CE2 4.36Å; W104-P226 HydrophobicContact CZ2-CB 4.15Å; W104-P226 HydrophobicContact CZ2-CG 4.1Å
105D98.9Very high98.9Very high0 Ų015.4 Ų15.40%07%0.065CC..Hα-helixtrans-58-46.5172.7-174.169.8000111.2W73 L101 F103 I107 E108 R109 L152 N290W73-D105 HydrophobicContact CH2-CB 4.31Å; W73-D105 WeakPolarHBondContact CH2-OD1 3.26Å; W73-D105 HydrophobicContact CZ2-CB 4.38Å; L101-D105 WeakPolarHBondContact O-CB 3.24Å; L101-D105 PolarHBondContact O-N 2.94Å; F103-D105 PolarHBondContact O-N 3.11Å; D105-I107 VanDerWaalsContact C-N 3.35Å; D105-I107 PolarHBondContact O-N 2.81Å; D105-E108 PolarHBondContact O-N 3.3Å; D105-R109 WeakPolarHBondContact O-CB 3.22Å; D105-R109 PolarHBondContact O-N 2.84Å; D105-R109 IonicContact OD1-CZ 2.69Å; D105-R109 IonicContact OD1-NE 2.72Å; D105-R109 IonicContact OD1-NH2 3.9Å; D105-R109 PolarHBondContact OD1-NH2 2.8Å; D105-R109 IonicContact OD2-CZ 2.74Å; D105-R109 IonicContact OD2-NE 2.74Å; D105-R109 PolarHBondContact OD2-NE 2.82Å; D105-R109 IonicContact OD2-NH2 3.32Å; D105-R109 PolarHBondContact OD2-NH2 2.94Å; D105-L152 HydrophobicContact CB-CD1 3.66Å; D105-L152 HydrophobicContact CB-CD2 4.31Å; D105-N290 WeakPolarHBondContact OD1-CB 3.36Å; D105-N290 PolarHBondContact OD1-ND2 3.19Å
106K98.7Very high98.9Very high0 Ų014.1 Ų14.10%06%0.06CC..Hα-helixtrans-62.2-44-176-163.662.355.9176.40111.6F102 F103 W104 C110 T140 N141 D142 M176 N177 L180F102-K106 WeakPolarHBondContact O-CB 3.37Å; F102-K106 PolarHBondContact O-N 3.45Å; F103-K106 PolarHBondContact O-N 2.85Å; W104-K106 VanDerWaalsContact C-N 3.32Å; W104-K106 PolarHBondContact O-N 3.12Å; K106-C110 WeakPolarHBondContact O-CB 3.46Å; K106-C110 PolarHBondContact O-N 3.17Å; K106-C110 VanDerWaalsContact O-N 3.13Å; K106-C110 PolarHBondContact O-SG 3.02Å; K106-T140 HydrophobicContact CD-CG2 4.34Å; K106-T140 PolarHBondContact NZ-O 3.1Å; K106-N141 PolarHBondContact NZ-O 3.42Å; K106-D142 IonicContact NZ-OD1 2.62Å; K106-D142 PolarHBondContact NZ-OD1 3.35Å; K106-M176 HydrophobicContact CG-CE 4.39Å; K106-N177 WeakPolarHBondContact CE-OD1 3.47Å; K106-N177 PolarHBondContact NZ-OD1 2.96Å; K106-L180 HydrophobicContact CD-CD1 3.75Å; K106-L180 HydrophobicContact CG-CD1 3.58Å
107I98.8Very high98.8Very high13 Ų1314.1 Ų14.17%0.0676%0.06CC..Hα-helixtrans-64.1-54.8177.4-59.8-53.7000110.7F103 W104 D105 R109 C110 Y111 I212 V215 F216 A219F103-I107 HydrophobicContact CD1-CG1 4.39Å; F103-I107 HydrophobicContact CE1-CG1 3.97Å; F103-I107 HydrophobicContact CZ-CG1 4.25Å; F103-I107 PolarHBondContact O-N 3.25Å; W104-I107 PolarHBondContact O-N 3.43Å; D105-I107 VanDerWaalsContact C-N 3.35Å; D105-I107 PolarHBondContact O-N 2.81Å; I107-R109 VanDerWaalsContact C-N 3.31Å; I107-R109 PolarHBondContact O-N 3.25Å; I107-C110 WeakPolarHBondContact O-CB 3.5Å; I107-C110 PolarHBondContact O-N 2.72Å; I107-Y111 PolarHBondContact O-N 2.83Å; I107-I212 HydrophobicContact CG2-CD1 4.28Å; I107-I212 HydrophobicContact CG2-CG1 4.26Å; I107-V215 HydrophobicContact CD1-CG1 3.82Å; I107-F216 HydrophobicContact CD1-CB 4.28Å; I107-F216 HydrophobicContact CD1-CD2 3.99Å; I107-F216 HydrophobicContact CD1-CG 4.41Å; I107-F216 HydrophobicContact CG1-CD2 4.11Å; I107-F216 HydrophobicContact CG2-CD2 4.34Å; I107-A219 HydrophobicContact CD1-CB 3.58Å
108E98.9Very high98.8Very high9 Ų914.7 Ų14.74%0.0426%0.063CC..Hα-helixtrans-64.6-37.5-174.4-72.4-80.1-150.300111.9W104 D105 Y111 Y112 K155 Y156 N290 M291W104-E108 WeakPolarHBondContact O-CB 3.05Å; W104-E108 WeakPolarHBondContact O-CG 3.42Å; W104-E108 PolarHBondContact O-N 3.22Å; D105-E108 PolarHBondContact O-N 3.3Å; E108-Y111 WeakPolarHBondContact O-CB 3.47Å; E108-Y111 PolarHBondContact O-N 2.91Å; E108-Y112 WeakPolarHBondContact O-CB 3.41Å; E108-Y112 PolarHBondContact O-N 3.12Å; E108-K155 WeakPolarHBondContact OE1-CE 3.43Å; E108-K155 IonicContact OE1-NZ 3.47Å; E108-K155 PolarHBondContact OE1-NZ 2.68Å; E108-Y156 HydrophobicContact CG-CE2 3.95Å; E108-Y156 PolarHBondContact OE1-OH 3.44Å; E108-N290 CarbonylContact C-O 3.5Å; E108-N290 WeakPolarHBondContact CB-O 3.49Å; E108-M291 HydrophobicContact CG-CE 4.03Å
109R98.8Very high98.8Very high23 Ų2318.8 Ų18.89%0.0878%0.082CC..Hα-helixtrans-65.2-42175.7-176.9-178.8-59.1-82.4-3.8112D105 I107 Y111 Y112 F113 N141 G143 M148 N290D105-R109 WeakPolarHBondContact O-CB 3.22Å; D105-R109 PolarHBondContact O-N 2.84Å; D105-R109 IonicContact OD1-CZ 2.69Å; D105-R109 IonicContact OD1-NE 2.72Å; D105-R109 IonicContact OD1-NH2 3.9Å; D105-R109 PolarHBondContact OD1-NH2 2.8Å; D105-R109 IonicContact OD2-CZ 2.74Å; D105-R109 IonicContact OD2-NE 2.74Å; D105-R109 PolarHBondContact OD2-NE 2.82Å; D105-R109 IonicContact OD2-NH2 3.32Å; D105-R109 PolarHBondContact OD2-NH2 2.94Å; I107-R109 VanDerWaalsContact C-N 3.31Å; I107-R109 PolarHBondContact O-N 3.25Å; R109-Y111 VanDerWaalsContact C-N 3.32Å; R109-Y112 PolarHBondContact O-N 3.15Å; R109-F113 WeakPolarHBondContact O-CB 3.19Å; R109-F113 PolarHBondContact O-N 3.45Å; R109-N141 PolarHBondContact NE-O 3.46Å; R109-G143 PolarHBondContact NH2-O 2.98Å; R109-G143 VanDerWaalsContact NH2-O 3.12Å; R109-M148 PolarHBondContact NH2-SD 3.37Å; R109-M148 VanDerWaalsContact NH2-SD 3.39Å; R109-N290 HydrophobicContact CB-CB 4.32Å; R109-N290 PolarHBondContact N-O 2.8Å; R109-N290 VanDerWaalsContact N-O 3.08Å
110C98.9Very high98.8Very high0 Ų018.9 Ų18.90%08%0.083CC..Hα-helixtrans-61.3-45.2173.6-700000110.4K106 I107 Y112 F113 L114 L184 I212 V215K106-C110 WeakPolarHBondContact O-CB 3.46Å; K106-C110 PolarHBondContact O-N 3.17Å; K106-C110 VanDerWaalsContact O-N 3.13Å; K106-C110 PolarHBondContact O-SG 3.02Å; I107-C110 WeakPolarHBondContact O-CB 3.5Å; I107-C110 PolarHBondContact O-N 2.72Å; C110-Y112 PolarHBondContact O-N 3.35Å; C110-F113 PolarHBondContact O-N 2.89Å; C110-L114 WeakPolarHBondContact O-CG 3.49Å; C110-L114 PolarHBondContact O-N 3.34Å; C110-L184 HydrophobicContact CB-CD1 4.36Å; C110-L184 HydrophobicContact CB-CD2 4.1Å; C110-I212 HydrophobicContact CB-CD1 4Å; C110-V215 HydrophobicContact CB-CB 4.47Å; C110-V215 HydrophobicContact CB-CG1 3.71Å; C110-V215 HydrophobicContact CB-CG2 4.1Å
111Y98.9Very high98.8Very high61 Ų6119.2 Ų19.224%0.2399%0.087CC..Hα-helixtrans-60.3-46.6176.7-172.6-119000111.6I107 E108 R109 F113 L114 H115 I208 I212 V292I107-Y111 PolarHBondContact O-N 2.83Å; E108-Y111 WeakPolarHBondContact O-CB 3.47Å; E108-Y111 PolarHBondContact O-N 2.91Å; R109-Y111 VanDerWaalsContact C-N 3.32Å; Y111-F113 VanDerWaalsContact C-N 3.33Å; Y111-F113 PolarHBondContact O-N 2.9Å; Y111-L114 PolarHBondContact O-N 3.04Å; Y111-H115 AromaticContact CE1-NE2 3.77Å; Y111-H115 AromaticContact CE2-CD2 3.9Å; Y111-H115 AromaticContact CE2-NE2 3.48Å; Y111-H115 WeakPolarHBondContact CE2-NE2 3.24Å; Y111-H115 AromaticContact CZ-CD2 3.79Å; Y111-H115 AromaticContact CZ-NE2 3.18Å; Y111-H115 PolarHBondContact O-CD2 3.09Å; Y111-H115 PolarHBondContact O-N 3.39Å; Y111-H115 PolarHBondContact OH-NE2 2.69Å; Y111-H115 VanDerWaalsContact OH-NE2 3.13Å; Y111-I208 HydrophobicContact CD2-CG2 3.69Å; Y111-I208 HydrophobicContact CE2-CG2 3.4Å; Y111-I208 VanDerWaalsContact CE2-CG2 3.4Å; Y111-I212 HydrophobicContact CD2-CB 4.42Å; Y111-I212 HydrophobicContact CD2-CD1 4.43Å; Y111-I212 HydrophobicContact CD2-CG1 4.26Å; Y111-V292 HydrophobicContact CD1-CB 4.05Å; Y111-V292 HydrophobicContact CD1-CG2 3.55Å; Y111-V292 HydrophobicContact CE1-CB 3.87Å; Y111-V292 HydrophobicContact CE1-CG1 4.48Å; Y111-V292 HydrophobicContact CE1-CG2 3.69Å; Y111-V292 HydrophobicContact CG-CG2 4.39Å
112Y98.8Very high98.8Very high56 Ų5624.5 Ų24.522%0.2211%0.111CC..Hα-helixtrans-55.9-45.5173.9-177.7-94000112.5E108 R109 C110 L114 H115 A116 F287 G289 V292E108-Y112 WeakPolarHBondContact O-CB 3.41Å; E108-Y112 PolarHBondContact O-N 3.12Å; R109-Y112 PolarHBondContact O-N 3.15Å; C110-Y112 PolarHBondContact O-N 3.35Å; Y112-L114 PolarHBondContact O-N 3.47Å; Y112-H115 PolarHBondContact O-N 2.6Å; Y112-A116 PolarHBondContact O-N 2.95Å; Y112-F287 WeakPolarHBondContact CE1-O 3.4Å; Y112-F287 WeakPolarHBondContact OH-CA 3.29Å; Y112-G289 WeakPolarHBondContact CD1-O 3.12Å; Y112-V292 HydrophobicContact CD2-CG2 4.34Å
113F98.8Very high98.8Very high11 Ų1129.2 Ų29.25%0.04813%0.129CC..Hα-helixtrans-63.7-38.6178174.3-94.5000113R109 C110 Y111 H115 A116 C117 L135 L136 P139 L184 C188R109-F113 WeakPolarHBondContact O-CB 3.19Å; R109-F113 PolarHBondContact O-N 3.45Å; C110-F113 PolarHBondContact O-N 2.89Å; Y111-F113 VanDerWaalsContact C-N 3.33Å; Y111-F113 PolarHBondContact O-N 2.9Å; F113-H115 VanDerWaalsContact C-N 3.32Å; F113-H115 PolarHBondContact O-N 3Å; F113-A116 WeakPolarHBondContact O-CB 3.35Å; F113-A116 PolarHBondContact O-N 3.19Å; F113-C117 WeakPolarHBondContact CE1-SG 3.37Å; F113-C117 WeakPolarHBondContact CZ-SG 3.37Å; F113-C117 PolarHBondContact O-N 2.85Å; F113-C117 PolarHBondContact O-SG 3.24Å; F113-L135 HydrophobicContact CE2-CB 3.92Å; F113-L135 VanDerWaalsContact CE2-O 3.3Å; F113-L135 WeakPolarHBondContact CE2-O 3.44Å; F113-L136 HydrophobicContact CZ-CD2 3.91Å; F113-P139 HydrophobicContact CD1-CB 4.08Å; F113-P139 HydrophobicContact CD2-CB 3.52Å; F113-P139 HydrophobicContact CE1-CB 4.11Å; F113-P139 HydrophobicContact CE2-CB 3.55Å; F113-P139 HydrophobicContact CE2-CG 4.36Å; F113-P139 HydrophobicContact CG-CB 3.79Å; F113-P139 HydrophobicContact CZ-CB 3.85Å; F113-P139 HydrophobicContact CZ-CG 4.27Å; F113-L184 HydrophobicContact CD1-CB 4.01Å; F113-L184 HydrophobicContact CD1-CD1 3.96Å; F113-L184 HydrophobicContact CD1-CD2 4.1Å; F113-L184 HydrophobicContact CD1-CG 4.26Å; F113-L184 HydrophobicContact CE1-CB 3.79Å; F113-L184 HydrophobicContact CE1-CD1 4.48Å; F113-L184 HydrophobicContact CG-CD1 4.42Å; F113-C188 HydrophobicContact CE1-CB 4.42Å; F113-C188 HydrophobicContact CZ-CB 4.44Å
114L98.9Very high98.8Very high0 Ų038 Ų380%017%0.168CC..Hα-helixtrans-62.7-41.3176.2-65.1175.8000111.4C110 Y111 Y112 C117 V118 L184 Y187 L191 I208 M211C110-L114 WeakPolarHBondContact O-CG 3.49Å; C110-L114 PolarHBondContact O-N 3.34Å; Y111-L114 PolarHBondContact O-N 3.04Å; Y112-L114 PolarHBondContact O-N 3.47Å; L114-C117 WeakPolarHBondContact O-CB 3.41Å; L114-C117 PolarHBondContact O-N 2.82Å; L114-V118 PolarHBondContact O-N 3.18Å; L114-L184 HydrophobicContact CD2-CD2 4.05Å; L114-L184 HydrophobicContact CG-CD2 4.39Å; L114-Y187 HydrophobicContact CD2-CD2 3.9Å; L114-Y187 HydrophobicContact CD2-CG 4.21Å; L114-L191 HydrophobicContact CB-CD1 4.01Å; L114-L191 HydrophobicContact CD2-CD1 3.78Å; L114-L191 HydrophobicContact CG-CD1 4.47Å; L114-I208 HydrophobicContact CB-CG1 4.31Å; L114-I208 HydrophobicContact CB-CG2 4.24Å; L114-I208 HydrophobicContact CD1-CG2 4.02Å; L114-M211 HydrophobicContact CD1-CB 3.78Å; L114-M211 HydrophobicContact CD1-SD 4.44Å; L114-M211 HydrophobicContact CD2-SD 4.14Å
115H98.8Very high98.7Very high65 Ų6538.4 Ų38.430%0.30117%0.171SC..Hα-helixtrans-64.7-39.7172.6-80.4-94.5000112Y111 Y112 F113 C117 V118 E119 V292Y111-H115 AromaticContact CE1-NE2 3.77Å; Y111-H115 AromaticContact CE2-CD2 3.9Å; Y111-H115 AromaticContact CE2-NE2 3.48Å; Y111-H115 WeakPolarHBondContact CE2-NE2 3.24Å; Y111-H115 AromaticContact CZ-CD2 3.79Å; Y111-H115 AromaticContact CZ-NE2 3.18Å; Y111-H115 PolarHBondContact O-CD2 3.09Å; Y111-H115 PolarHBondContact O-N 3.39Å; Y111-H115 PolarHBondContact OH-NE2 2.69Å; Y111-H115 VanDerWaalsContact OH-NE2 3.13Å; Y112-H115 PolarHBondContact O-N 2.6Å; F113-H115 VanDerWaalsContact C-N 3.32Å; F113-H115 PolarHBondContact O-N 3Å; H115-C117 VanDerWaalsContact C-N 3.29Å; H115-C117 PolarHBondContact O-N 3.14Å; H115-V118 PolarHBondContact O-N 2.9Å; H115-E119 PolarHBondContact O-N 2.71Å; H115-V292 HydrophobicContact CB-CG2 3.99Å
116A98.7Very high98.7Very high4 Ų441.5 Ų41.53%0.03319%0.191CC..Hα-helixtrans-62-35173.300000112.7Y112 F113 E119 T120 L135 F287Y112-A116 PolarHBondContact O-N 2.95Å; F113-A116 WeakPolarHBondContact O-CB 3.35Å; F113-A116 PolarHBondContact O-N 3.19Å; A116-E119 PolarHBondContact O-N 3.38Å; A116-T120 WeakPolarHBondContact O-CB 3.07Å; A116-T120 VanDerWaalsContact O-CG2 3.32Å; A116-T120 WeakPolarHBondContact O-CG2 3.33Å; A116-T120 PolarHBondContact O-N 2.77Å; A116-T120 PolarHBondContact O-OG1 3.29Å; A116-L135 HydrophobicContact CB-CD1 4.48Å; A116-F287 HydrophobicContact CB-CD1 3.55Å; A116-F287 HydrophobicContact CB-CE1 3.74Å
117C98.8Very high98.7Very high2 Ų245 Ų451%0.01421%0.213CC..Hα-helixtrans-63-43.9173.7-67.60000111.7F113 L114 H115 T120 A121 C188 L191F113-C117 WeakPolarHBondContact CE1-SG 3.37Å; F113-C117 WeakPolarHBondContact CZ-SG 3.37Å; F113-C117 PolarHBondContact O-N 2.85Å; F113-C117 PolarHBondContact O-SG 3.24Å; L114-C117 WeakPolarHBondContact O-CB 3.41Å; L114-C117 PolarHBondContact O-N 2.82Å; H115-C117 VanDerWaalsContact C-N 3.29Å; H115-C117 PolarHBondContact O-N 3.14Å; C117-T120 PolarHBondContact O-OG1 3.22Å; C117-A121 VanDerWaalsContact O-CB 3.27Å; C117-A121 WeakPolarHBondContact O-CB 3.27Å; C117-A121 PolarHBondContact O-N 3.35Å; C117-C188 HydrophobicContact CB-CB 4.47Å; C117-C188 VanDerWaalsContact SG-CB 3.59Å; C117-C188 PolarHBondContact SG-SG 3.02Å; C117-L191 HydrophobicContact CB-CD1 4.12Å
118V98.8Very high98.6Very high13 Ų1350.6 Ų50.68%0.07924%0.243CC..Hα-helixtrans-64.7-47.1176.2174.30000110.6L114 H115 A121 Q122 L191 V195 L204 I208L114-V118 PolarHBondContact O-N 3.18Å; H115-V118 PolarHBondContact O-N 2.9Å; V118-A121 WeakPolarHBondContact O-CB 3.39Å; V118-A121 PolarHBondContact O-N 3.43Å; V118-Q122 HydrophobicContact CG1-CG 4.41Å; V118-Q122 VanDerWaalsContact O-CG 3.31Å; V118-Q122 WeakPolarHBondContact O-CG 3.22Å; V118-Q122 PolarHBondContact O-N 3.22Å; V118-L191 HydrophobicContact CG2-CB 4.22Å; V118-L191 HydrophobicContact CG2-CD1 4.21Å; V118-L191 HydrophobicContact CG2-CD2 4.11Å; V118-L191 HydrophobicContact CG2-CG 4.41Å; V118-V195 HydrophobicContact CG1-CG2 4.13Å; V118-L204 HydrophobicContact CG1-CD1 4.12Å; V118-L204 HydrophobicContact CG2-CD2 4.3Å; V118-I208 HydrophobicContact CG2-CD1 4.15Å
119E98.7Very high98.6Very high87 Ų8750.9 Ų50.941%0.40725%0.248SC..Hα-helixtrans-60.3-49.3-179.7-170-167.6135.400111.7H115 A116 A121 Q122 R123 F287H115-E119 PolarHBondContact O-N 2.71Å; A116-E119 PolarHBondContact O-N 3.38Å; E119-A121 VanDerWaalsContact C-N 3.3Å; E119-A121 PolarHBondContact O-N 2.92Å; E119-Q122 PolarHBondContact O-N 3.04Å; E119-R123 WeakPolarHBondContact O-CG 3.36Å; E119-R123 PolarHBondContact O-N 3.26Å; E119-R123 IonicContact OE1-NH1 2.94Å; E119-R123 PolarHBondContact OE1-NH1 3.19Å; E119-F287 HydrophobicContact CB-CE1 4.45Å; E119-F287 HydrophobicContact CG-CZ 4.43Å; E119-F287 VanDerWaalsContact OE1-CZ 3.28Å; E119-F287 WeakPolarHBondContact OE1-CZ 3.17Å; E119-F287 WeakPolarHBondContact OE2-CE1 3.47Å
120T98.8Very high98.6Very high1 Ų157.8 Ų57.81%0.00627%0.274CS..Hα-helixtrans-66.2-31.817954.80000112.5A116 C117 K124 E125 L131 L135 F287A116-T120 WeakPolarHBondContact O-CB 3.07Å; A116-T120 VanDerWaalsContact O-CG2 3.32Å; A116-T120 WeakPolarHBondContact O-CG2 3.33Å; A116-T120 PolarHBondContact O-N 2.77Å; A116-T120 PolarHBondContact O-OG1 3.29Å; C117-T120 PolarHBondContact O-OG1 3.22Å; T120-K124 PolarHBondContact O-N 2.87Å; T120-E125 HydrophobicContact CG2-CG 4.48Å; T120-E125 WeakPolarHBondContact O-CB 3.2Å; T120-E125 PolarHBondContact O-N 2.72Å; T120-L131 HydrophobicContact CG2-CD2 3.98Å; T120-L131 HydrophobicContact CG2-CG 4.33Å; T120-L135 HydrophobicContact CG2-CD1 3.89Å; T120-F287 HydrophobicContact CG2-CE1 4.41Å; T120-F287 HydrophobicContact CG2-CE2 3.99Å; T120-F287 HydrophobicContact CG2-CZ 3.72Å
121A98.8Very high98.6Very high13 Ų1358.1 Ų58.111%0.10728%0.276CS..Hα-helixtrans-64.8-45.3171.400000111.8C117 V118 E119 R123 K124 R192 V195C117-A121 VanDerWaalsContact O-CB 3.27Å; C117-A121 WeakPolarHBondContact O-CB 3.27Å; C117-A121 PolarHBondContact O-N 3.35Å; V118-A121 WeakPolarHBondContact O-CB 3.39Å; V118-A121 PolarHBondContact O-N 3.43Å; E119-A121 VanDerWaalsContact C-N 3.3Å; E119-A121 PolarHBondContact O-N 2.92Å; A121-R123 VanDerWaalsContact C-N 3.3Å; A121-R123 PolarHBondContact O-N 2.77Å; A121-K124 WeakPolarHBondContact O-CA 3.08Å; A121-K124 PolarHBondContact O-N 3.17Å; A121-R192 HydrophobicContact CB-CB 4.42Å; A121-R192 HydrophobicContact CB-CG 3.92Å; A121-V195 HydrophobicContact CB-CB 3.83Å; A121-V195 HydrophobicContact CB-CG1 3.8Å; A121-V195 HydrophobicContact CB-CG2 3.97Å
122Q98.6Very high98.6Very high112 Ų11255.4 Ų55.452%0.52327%0.265SS..Hα-helixtrans-64.3-35.7178-72.3171.1-1000112V118 E119 K124 V195V118-Q122 HydrophobicContact CG1-CG 4.41Å; V118-Q122 VanDerWaalsContact O-CG 3.31Å; V118-Q122 WeakPolarHBondContact O-CG 3.22Å; V118-Q122 PolarHBondContact O-N 3.22Å; E119-Q122 PolarHBondContact O-N 3.04Å; Q122-K124 PolarHBondContact O-N 3.45Å; Q122-V195 HydrophobicContact CG-CG1 3.92Å; Q122-V195 HydrophobicContact CG-CG2 4.48Å
123R98.4Very high98.6Very high99 Ų9957.3 Ų57.337%0.37428%0.276SS..THydrogen-bonded Turntrans-69.7-5171.1-71165.954.2164.7-1.8113.8E119 A121 E125 E286E119-R123 WeakPolarHBondContact O-CG 3.36Å; E119-R123 PolarHBondContact O-N 3.26Å; E119-R123 IonicContact OE1-NH1 2.94Å; E119-R123 PolarHBondContact OE1-NH1 3.19Å; A121-R123 VanDerWaalsContact C-N 3.3Å; A121-R123 PolarHBondContact O-N 2.77Å; R123-E125 HydrophobicContact CB-CG 4Å; R123-E125 IonicContact CZ-OE1 3.1Å; R123-E125 IonicContact NE-OE1 3.36Å; R123-E125 IonicContact NH2-OE1 3.61Å; R123-E125 PolarHBondContact NH2-OE1 3.38Å; R123-E125 VanDerWaalsContact NH2-OE1 3.1Å; R123-E125 PolarHBondContact O-N 3.2Å; R123-E286 IonicContact CZ-OE1 2.96Å; R123-E286 VanDerWaalsContact CZ-OE1 3.28Å; R123-E286 IonicContact NH1-OE1 3.75Å; R123-E286 PolarHBondContact NH1-OE1 2.99Å; R123-E286 IonicContact NH2-OE1 2.7Å; R123-E286 PolarHBondContact NH2-OE1 3.46Å
124K98.4Very high98.6Very high186 Ų18660.7 Ų60.781%0.80929%0.291SS*.THydrogen-bonded Turntrans5930.7-176.4-53.7-178.7179.8-178.70113.2T120 A121 Q122T120-K124 PolarHBondContact O-N 2.87Å; A121-K124 WeakPolarHBondContact O-CA 3.08Å; A121-K124 PolarHBondContact O-N 3.17Å; Q122-K124 PolarHBondContact O-N 3.45Å
125E98.6Very high98.6Very high51 Ų5161.7 Ų61.724%0.23830%0.296CS..  trans-64.3127.8173.2-66-72.7174.600109.1T120 R123 L131 V132 R192T120-E125 HydrophobicContact CG2-CG 4.48Å; T120-E125 WeakPolarHBondContact O-CB 3.2Å; T120-E125 PolarHBondContact O-N 2.72Å; R123-E125 HydrophobicContact CB-CG 4Å; R123-E125 IonicContact CZ-OE1 3.1Å; R123-E125 IonicContact NE-OE1 3.36Å; R123-E125 IonicContact NH2-OE1 3.61Å; R123-E125 PolarHBondContact NH2-OE1 3.38Å; R123-E125 VanDerWaalsContact NH2-OE1 3.1Å; R123-E125 PolarHBondContact O-N 3.2Å; E125-L131 HydrophobicContact CG-CD2 4.02Å; E125-V132 HydrophobicContact CB-CG2 3.76Å; E125-R192 PolarHBondContact O-NH1 3.03Å; E125-R192 PolarHBondContact O-NH2 3.23Å
126P98.3Very high98.6Very high65 Ų6559.7 Ų59.742%0.42229%0.288SS..  trans-68.8145.6-178.626.7-31000110.8D128 G129 V132P126-D128 VanDerWaalsContact C-N 3.29Å; P126-D128 PolarHBondContact O-N 3.05Å; P126-G129 WeakPolarHBondContact O-CA 3.42Å; P126-G129 PolarHBondContact O-N 3.28Å; P126-V132 WeakPolarHBondContact O-CG2 3.38Å
127V97.9Very high98.5Very high74 Ų7462.9 Ų62.945%0.44831%0.31SS..THydrogen-bonded Turntrans-65.4-34.1-174.765.60000112.4G129 V132 Q133V127-G129 VanDerWaalsContact C-N 3.28Å; V127-V132 HydrophobicContact CG2-CG1 4.21Å; V127-Q133 PolarHBondContact O-NE2 2.85Å
128D98.2Very high98.5Very high131 Ų13166 Ų6670%0.70133%0.326SS*.THydrogen-bonded Turntrans-86.21.7173.260.9-22.8000112.8P126P126-D128 VanDerWaalsContact C-N 3.29Å; P126-D128 PolarHBondContact O-N 3.05Å
129G98.7Very high98.4Very high14 Ų1465.9 Ų65.914%0.14433%0.326CS..SBendtrans-68.8154.2172.900000112.8P126 V127 L131 V132 Q133P126-G129 WeakPolarHBondContact O-CA 3.42Å; P126-G129 PolarHBondContact O-N 3.28Å; V127-G129 VanDerWaalsContact C-N 3.28Å; G129-L131 VanDerWaalsContact C-N 3.3Å; G129-L131 PolarHBondContact O-N 3.12Å; G129-V132 PolarHBondContact O-N 3.29Å; G129-Q133 WeakPolarHBondContact O-CB 3.49Å; G129-Q133 WeakPolarHBondContact O-CG 3.27Å; G129-Q133 PolarHBondContact O-N 2.85Å
130R98.6Very high98.2Very high169 Ų16961.8 Ų61.864%0.63831%0.306SS*.Hα-helixtrans-54.3-43.7-176.3-172.2177.1-175.6175.24113.1F134 W445R130-F134 VanDerWaalsContact O-CB 3.23Å; R130-F134 WeakPolarHBondContact O-CB 3.34Å; R130-F134 PolarHBondContact O-N 3.32Å; R130-W445 HydrophobicContact CB-CH2 4.41Å; R130-W445 HydrophobicContact CB-CZ3 4.27Å; R130-W445 HydrophobicContact CG-CD2 4.18Å; R130-W445 HydrophobicContact CG-CE3 3.9Å; R130-W445 HydrophobicContact CG-CH2 4.07Å; R130-W445 HydrophobicContact CG-CZ2 4.34Å; R130-W445 HydrophobicContact CG-CZ3 3.85Å; R130-W445 VanDerWaalsContact CZ-CE2 3.42Å; R130-W445 VanDerWaalsContact NE-CE2 3.28Å; R130-W445 VanDerWaalsContact NH2-CD1 3.27Å
131L98.7Very high98Very high7 Ų764.2 Ų64.24%0.03732%0.319CS..Hα-helixtrans-64.6-53.4-178.4176.656.8000111.7T120 E125 G129 Q133 F134 L135 F287 A444 W445T120-L131 HydrophobicContact CG2-CD2 3.98Å; T120-L131 HydrophobicContact CG2-CG 4.33Å; E125-L131 HydrophobicContact CG-CD2 4.02Å; G129-L131 VanDerWaalsContact C-N 3.3Å; G129-L131 PolarHBondContact O-N 3.12Å; L131-Q133 PolarHBondContact O-N 2.94Å; L131-F134 WeakPolarHBondContact O-CB 3.22Å; L131-F134 PolarHBondContact O-N 3.32Å; L131-L135 HydrophobicContact CD1-CD1 4.21Å; L131-L135 HydrophobicContact CD1-CG 4.24Å; L131-L135 HydrophobicContact CG-CD1 4.38Å; L131-L135 WeakPolarHBondContact O-CG 3.28Å; L131-L135 PolarHBondContact O-N 2.91Å; L131-F287 HydrophobicContact CD1-CD2 3.9Å; L131-F287 HydrophobicContact CD1-CE2 4.15Å; L131-F287 HydrophobicContact CD2-CE2 3.94Å; L131-A444 HydrophobicContact CD1-CB 3.68Å; L131-W445 HydrophobicContact CB-CZ3 4.08Å; L131-W445 HydrophobicContact CD1-CZ3 4.39Å
132V98.7Very high98Very high3 Ų363.8 Ų63.82%0.01832%0.316CS..Hα-helixtrans-65.2-41.4-177.7179.50000110.9E125 P126 V127 G129 F134 L135 L136E125-V132 HydrophobicContact CB-CG2 3.76Å; P126-V132 WeakPolarHBondContact O-CG2 3.38Å; V127-V132 HydrophobicContact CG2-CG1 4.21Å; G129-V132 PolarHBondContact O-N 3.29Å; V132-F134 VanDerWaalsContact C-N 3.34Å; V132-F134 PolarHBondContact O-N 3.44Å; V132-L135 PolarHBondContact O-N 3.15Å; V132-L136 HydrophobicContact CG1-CD1 3.73Å; V132-L136 HydrophobicContact CG1-CG 4.33Å; V132-L136 WeakPolarHBondContact O-CB 3.26Å; V132-L136 VanDerWaalsContact O-CG 3.27Å; V132-L136 WeakPolarHBondContact O-CG 3.44Å; V132-L136 PolarHBondContact O-N 3.07Å
133Q98.8Very high98Very high97 Ų9758.7 Ų58.745%0.45329%0.293SS..Hα-helixtrans-64.1-36.8175.1-71.6-61.6-52.300112.7V127 G129 L131 L136 S137V127-Q133 PolarHBondContact O-NE2 2.85Å; G129-Q133 WeakPolarHBondContact O-CB 3.49Å; G129-Q133 WeakPolarHBondContact O-CG 3.27Å; G129-Q133 PolarHBondContact O-N 2.85Å; L131-Q133 PolarHBondContact O-N 2.94Å; Q133-L136 PolarHBondContact O-N 2.83Å; Q133-S137 PolarHBondContact O-N 3.35Å; Q133-S137 VanDerWaalsContact O-N 3.09Å
134F98.6Very high97.9Very high82 Ų8254.1 Ų54.136%0.3628%0.277SS..Hα-helixtrans-62.2-49.5173172.7-99.9000111.3R130 L131 V132 L136 S137 A444 W445R130-F134 VanDerWaalsContact O-CB 3.23Å; R130-F134 WeakPolarHBondContact O-CB 3.34Å; R130-F134 PolarHBondContact O-N 3.32Å; L131-F134 WeakPolarHBondContact O-CB 3.22Å; L131-F134 PolarHBondContact O-N 3.32Å; V132-F134 VanDerWaalsContact C-N 3.34Å; V132-F134 PolarHBondContact O-N 3.44Å; F134-L136 VanDerWaalsContact C-N 3.27Å; F134-L136 PolarHBondContact O-N 3.36Å; F134-S137 VanDerWaalsContact O-CB 3.3Å; F134-S137 WeakPolarHBondContact O-CB 3.41Å; F134-S137 PolarHBondContact O-N 2.69Å; F134-S137 VanDerWaalsContact O-N 3.09Å; F134-S137 PolarHBondContact O-OG 2.8Å; F134-A444 HydrophobicContact CD1-CB 3.73Å; F134-A444 VanDerWaalsContact CE1-C 3.41Å; F134-A444 HydrophobicContact CE1-CB 3.74Å; F134-A444 WeakPolarHBondContact CE1-O 3.33Å; F134-A444 WeakPolarHBondContact CZ-O 3.33Å; F134-W445 HydrophobicContact CB-CE3 4.46Å; F134-W445 HydrophobicContact CD1-CB 4.5Å; F134-W445 HydrophobicContact CD2-CB 3.63Å; F134-W445 HydrophobicContact CE2-CB 3.78Å; F134-W445 HydrophobicContact CG-CB 4.02Å; F134-W445 HydrophobicContact CZ-CB 4.29Å
135L98.6Very high98Very high20 Ų2045.3 Ų45.311%0.10524%0.239CC..Hα-helixtrans-60.1-37.1178.1-65.3177.6000111.9F113 A116 T120 L131 V132 S137 F287F113-L135 HydrophobicContact CE2-CB 3.92Å; F113-L135 VanDerWaalsContact CE2-O 3.3Å; F113-L135 WeakPolarHBondContact CE2-O 3.44Å; A116-L135 HydrophobicContact CB-CD1 4.48Å; T120-L135 HydrophobicContact CG2-CD1 3.89Å; L131-L135 HydrophobicContact CD1-CD1 4.21Å; L131-L135 HydrophobicContact CD1-CG 4.24Å; L131-L135 HydrophobicContact CG-CD1 4.38Å; L131-L135 WeakPolarHBondContact O-CG 3.28Å; L131-L135 PolarHBondContact O-N 2.91Å; V132-L135 PolarHBondContact O-N 3.15Å; L135-S137 VanDerWaalsContact C-N 3.32Å; L135-S137 PolarHBondContact O-N 2.69Å; L135-F287 HydrophobicContact CD1-CD2 4.41Å; L135-F287 HydrophobicContact CD1-CG 4.42Å; L135-F287 HydrophobicContact CD2-CB 3.75Å; L135-F287 HydrophobicContact CD2-CG 4.19Å
136L98.6Very high97.9Very high24 Ų2443 Ų4313%0.12623%0.228CC..Hα-helixtrans-77.8-11.5178.4-68.9168.9000114.4F113 V132 Q133 F134 R185 C188F113-L136 HydrophobicContact CZ-CD2 3.91Å; V132-L136 HydrophobicContact CG1-CD1 3.73Å; V132-L136 HydrophobicContact CG1-CG 4.33Å; V132-L136 WeakPolarHBondContact O-CB 3.26Å; V132-L136 VanDerWaalsContact O-CG 3.27Å; V132-L136 WeakPolarHBondContact O-CG 3.44Å; V132-L136 PolarHBondContact O-N 3.07Å; Q133-L136 PolarHBondContact O-N 2.83Å; F134-L136 VanDerWaalsContact C-N 3.27Å; F134-L136 PolarHBondContact O-N 3.36Å; L136-R185 HydrophobicContact CD2-CB 4.36Å; L136-R185 HydrophobicContact CD2-CG 3.83Å; L136-R185 PolarHBondContact O-NE 3.15Å; L136-R185 PolarHBondContact O-NH2 2.88Å; L136-C188 HydrophobicContact CD2-CB 3.77Å
137S98Very high98Very high71 Ų7140.1 Ų40.150%0.49721%0.208SC..Hα-helixtrans-64.8-46-174.4700000112.3Q133 F134 L135 R185Q133-S137 PolarHBondContact O-N 3.35Å; Q133-S137 VanDerWaalsContact O-N 3.09Å; F134-S137 VanDerWaalsContact O-CB 3.3Å; F134-S137 WeakPolarHBondContact O-CB 3.41Å; F134-S137 PolarHBondContact O-N 2.69Å; F134-S137 VanDerWaalsContact O-N 3.09Å; F134-S137 PolarHBondContact O-OG 2.8Å; L135-S137 VanDerWaalsContact C-N 3.32Å; L135-S137 PolarHBondContact O-N 2.69Å; S137-R185 PolarHBondContact O-NH2 2.67Å
138N97.4Very high98Very high66 Ų6636.6 Ų36.635%0.35319%0.187SC..  trans-156.269.4175.8-171.922.1000111.9T140 N141 N181N138-T140 PolarHBondContact O-N 3.29Å; N138-N141 WeakPolarHBondContact ND2-CB 3.41Å; N138-N141 PolarHBondContact O-N 3.19Å; N138-N141 VanDerWaalsContact O-N 3.14Å; N138-N181 PolarHBondContact OD1-ND2 3.4Å
139P96.4Very high98Very high12 Ų1230.4 Ų30.48%0.07815%0.154CC..THydrogen-bonded Turntrans-63.9-23.8-175.325.2-35.2000114F113 N181 L184F113-P139 HydrophobicContact CD1-CB 4.08Å; F113-P139 HydrophobicContact CD2-CB 3.52Å; F113-P139 HydrophobicContact CE1-CB 4.11Å; F113-P139 HydrophobicContact CE2-CB 3.55Å; F113-P139 HydrophobicContact CE2-CG 4.36Å; F113-P139 HydrophobicContact CG-CB 3.79Å; F113-P139 HydrophobicContact CZ-CB 3.85Å; F113-P139 HydrophobicContact CZ-CG 4.27Å; P139-N181 WeakPolarHBondContact CD-OD1 3.4Å; P139-N181 WeakPolarHBondContact CG-OD1 3.18Å; P139-L184 HydrophobicContact CB-CB 4.45Å; P139-L184 HydrophobicContact CB-CD1 3.71Å; P139-L184 HydrophobicContact CG-CB 4Å; P139-L184 HydrophobicContact CG-CD1 3.9Å
140T95.2Very high98Very high0 Ų029.8 Ų29.80%015%0.147CC..THydrogen-bonded Turntrans-101.539.3173.169.50000113.3K106 N138 D142 N177 L180 N181 L184K106-T140 HydrophobicContact CD-CG2 4.34Å; K106-T140 PolarHBondContact NZ-O 3.1Å; N138-T140 PolarHBondContact O-N 3.29Å; T140-D142 PolarHBondContact O-N 3.11Å; T140-N177 PolarHBondContact O-OD1 2.79Å; T140-N177 PolarHBondContact OG1-O 3.31Å; T140-L180 HydrophobicContact CG2-CB 3.48Å; T140-L180 VanDerWaalsContact CG2-CB 3.48Å; T140-L180 HydrophobicContact CG2-CD1 4.3Å; T140-N181 PolarHBondContact N-OD1 3.12Å; T140-N181 PolarHBondContact OG1-ND2 3.4Å; T140-N181 PolarHBondContact OG1-OD1 2.91Å; T140-L184 HydrophobicContact CG2-CD1 3.41Å; T140-L184 VanDerWaalsContact CG2-CD1 3.41Å; T140-L184 HydrophobicContact CG2-CG 4.36Å
141N95.1Very high98.1Very high52 Ų5222.3 Ų22.328%0.27812%0.12SC..  trans-51.8141.6170.8-163.5-2.1000110.2K106 R109 N138 G143 A452K106-N141 PolarHBondContact NZ-O 3.42Å; R109-N141 PolarHBondContact NE-O 3.46Å; N138-N141 WeakPolarHBondContact ND2-CB 3.41Å; N138-N141 PolarHBondContact O-N 3.19Å; N138-N141 VanDerWaalsContact O-N 3.14Å; N141-G143 VanDerWaalsContact C-N 3.3Å; N141-G143 PolarHBondContact OD1-N 3.4Å; N141-G143 VanDerWaalsContact OD1-N 3.1Å; N141-A452 PolarHBondContact ND2-O 3.29Å; N141-A452 PolarHBondContact OD1-O 3.14Å
142D98.6Very high98.1Very high5 Ų522 Ų223%0.02712%0.118CC..SBendtrans-76.3-25.5171.7-72.3-6.9000111.6G70 W73 F102 K106 T140 S173 N177G70-D142 PolarHBondContact N-OD2 3.11Å; G70-D142 CarbonylContact O-C 3.41Å; W73-D142 PolarHBondContact NE1-O 2.74Å; F102-D142 HydrophobicContact CE2-CB 4.1Å; F102-D142 VanDerWaalsContact CE2-OD1 3.25Å; F102-D142 WeakPolarHBondContact CE2-OD1 3.2Å; F102-D142 VanDerWaalsContact CZ-OD1 3.29Å; F102-D142 WeakPolarHBondContact CZ-OD1 3.27Å; K106-D142 IonicContact NZ-OD1 2.62Å; K106-D142 PolarHBondContact NZ-OD1 3.35Å; T140-D142 PolarHBondContact O-N 3.11Å; D142-S173 WeakPolarHBondContact OD2-CB 3.4Å; D142-S173 PolarHBondContact OD2-OG 2.83Å; D142-N177 PolarHBondContact OD1-ND2 2.98Å; D142-N177 PolarHBondContact OD1-OD1 2.77Å
143G97.5Very high98.1Very high5 Ų521.8 Ų21.85%0.05212%0.117CC..  trans-62.7151.9178.700000115.1R109 N141 L451R109-G143 PolarHBondContact NH2-O 2.98Å; R109-G143 VanDerWaalsContact NH2-O 3.12Å; N141-G143 VanDerWaalsContact C-N 3.3Å; N141-G143 PolarHBondContact OD1-N 3.4Å; N141-G143 VanDerWaalsContact OD1-N 3.1Å; G143-L451 CarbonylContact C-O 3.54Å; G143-L451 WeakPolarHBondContact CA-O 3.46Å
144G98.1Very high98.1Very high3 Ų319 Ų193%0.03111%0.105CC..  trans-166.8175-178.300000113W73 M148 L451W73-G144 VanDerWaalsContact CE3-C 3.49Å; G144-M148 VanDerWaalsContact CA-SD 3.6Å; G144-L451 PolarHBondContact N-O 3.4Å; G144-L451 WeakPolarHBondContact O-CB 3.42Å; G144-L451 WeakPolarHBondContact O-CD1 3.43Å
145Q98.5Very high98.1Very high1 Ų119.4 Ų19.41%0.00511%0.106CC..  trans-118.6172.2-171.2-62.9-66.1-7.400112.2D147 M148 L149 L288 T297 Y299 M369 E419 G449 S450Q145-D147 PolarHBondContact O-N 3.11Å; Q145-M148 HydrophobicContact CB-CE 4.38Å; Q145-M148 HydrophobicContact CB-CG 4.41Å; Q145-M148 HydrophobicContact CB-SD 4.38Å; Q145-M148 HydrophobicContact CG-CE 4.24Å; Q145-M148 PolarHBondContact N-SD 2.96Å; Q145-M148 WeakPolarHBondContact O-CB 3.41Å; Q145-M148 PolarHBondContact O-N 2.96Å; Q145-M148 VanDerWaalsContact O-N 3.17Å; Q145-L149 PolarHBondContact O-N 3.07Å; Q145-L288 HydrophobicContact CG-CD1 4.41Å; Q145-L288 HydrophobicContact CG-CD2 4.02Å; Q145-L288 HydrophobicContact CG-CG 4.34Å; Q145-T297 HydrophobicContact CB-CG2 3.8Å; Q145-T297 HydrophobicContact CG-CG2 4.02Å; Q145-Y299 WeakPolarHBondContact CG-OH 3.45Å; Q145-Y299 PolarHBondContact NE2-OH 3.42Å; Q145-Y299 PolarHBondContact OE1-OH 2.88Å; Q145-M369 VanDerWaalsContact NE2-CE 3.31Å; Q145-M369 VanDerWaalsContact OE1-CE 3.29Å; Q145-E419 PolarHBondContact OE1-OE2 2.8Å; Q145-G449 PolarHBondContact NE2-O 3.05Å; Q145-S450 PolarHBondContact NE2-O 3.25Å
146W98.6Very high98.1Very high2 Ų220 Ų201%0.00811%0.107CC..Hα-helixtrans-56.8-51-178.6-177.5-104.2000114C77 M148 L149 V150 Y261 I263 K266 C268 W322 V421C77-W146 HydrophobicContact CB-CZ3 4.39Å; W146-M148 PolarHBondContact O-N 3.49Å; W146-L149 HydrophobicContact CE3-CD1 3.92Å; W146-L149 HydrophobicContact CZ3-CD1 4.32Å; W146-L149 WeakPolarHBondContact O-CA 3.32Å; W146-L149 VanDerWaalsContact O-CB 3.29Å; W146-L149 WeakPolarHBondContact O-CB 3.17Å; W146-L149 PolarHBondContact O-N 3.01Å; W146-V150 PolarHBondContact O-N 3.28Å; W146-V150 VanDerWaalsContact O-N 3.1Å; W146-Y261 HydrophobicContact CH2-CE1 4.32Å; W146-I263 HydrophobicContact CH2-CD1 4.12Å; W146-I263 HydrophobicContact CH2-CG1 3.77Å; W146-I263 HydrophobicContact CZ2-CD1 3.95Å; W146-I263 HydrophobicContact CZ2-CG1 3.28Å; W146-K266 HydrophobicContact CH2-CB 4.49Å; W146-K266 HydrophobicContact CH2-CG 4.41Å; W146-K266 HydrophobicContact CZ2-CB 3.54Å; W146-K266 HydrophobicContact CZ2-CG 3.75Å; W146-C268 HydrophobicContact CB-CB 4.47Å; W146-W322 HydrophobicContact CE3-CD2 4.25Å; W146-W322 HydrophobicContact CE3-CG 4.24Å; W146-W322 HydrophobicContact CZ3-CB 4.17Å; W146-W322 HydrophobicContact CZ3-CG 4.15Å; W146-V421 HydrophobicContact CB-CG2 3.92Å; W146-V421 HydrophobicContact CD2-CB 4.17Å; W146-V421 HydrophobicContact CD2-CG1 3.59Å; W146-V421 HydrophobicContact CD2-CG2 3.7Å; W146-V421 VanDerWaalsContact CE2-CG1 3.42Å; W146-V421 HydrophobicContact CE3-CB 4.19Å; W146-V421 HydrophobicContact CE3-CG1 3.88Å; W146-V421 HydrophobicContact CE3-CG2 3.88Å; W146-V421 HydrophobicContact CG-CG1 4.16Å; W146-V421 HydrophobicContact CG-CG2 3.68Å; W146-V421 HydrophobicContact CH2-CG1 3.84Å; W146-V421 HydrophobicContact CZ2-CG1 3.56Å; W146-V421 HydrophobicContact CZ3-CB 4.48Å; W146-V421 HydrophobicContact CZ3-CG1 3.99Å
147D98.6Very high98.1Very high4 Ų418.8 Ų18.82%0.02110%0.101CC..Hα-helixtrans-64.3-25.1-179.8-75.1-68.9000112.9Q145 L149 V150 N151 R295 L298Q145-D147 PolarHBondContact O-N 3.11Å; D147-L149 VanDerWaalsContact C-N 3.33Å; D147-V150 WeakPolarHBondContact O-CB 3.3Å; D147-V150 PolarHBondContact O-N 3.48Å; D147-N151 VanDerWaalsContact O-CG 3.3Å; D147-N151 PolarHBondContact O-N 2.8Å; D147-N151 PolarHBondContact O-ND2 2.81Å; D147-R295 HydrophobicContact CB-CB 4.47Å; D147-R295 IonicContact OD1-CZ 2.96Å; D147-R295 IonicContact OD1-NE 2.84Å; D147-R295 PolarHBondContact OD1-NE 3.36Å; D147-R295 VanDerWaalsContact OD1-NE 3.14Å; D147-R295 IonicContact OD1-NH2 3.14Å; D147-R295 PolarHBondContact OD1-NH2 3.35Å; D147-L298 PolarHBondContact OD2-N 2.97Å
148M98.8Very high98.1Very high1 Ų115.5 Ų15.51%0.0058%0.078CC..Hα-helixtrans-66.3-36.3172-64.9180-168.800111.4W73 R109 G144 Q145 W146 L152 L288 N290W73-M148 HydrophobicContact CH2-CB 4.16Å; W73-M148 HydrophobicContact CZ3-CB 3.7Å; R109-M148 PolarHBondContact NH2-SD 3.37Å; R109-M148 VanDerWaalsContact NH2-SD 3.39Å; G144-M148 VanDerWaalsContact CA-SD 3.6Å; Q145-M148 HydrophobicContact CB-CE 4.38Å; Q145-M148 HydrophobicContact CB-CG 4.41Å; Q145-M148 HydrophobicContact CB-SD 4.38Å; Q145-M148 HydrophobicContact CG-CE 4.24Å; Q145-M148 PolarHBondContact N-SD 2.96Å; Q145-M148 WeakPolarHBondContact O-CB 3.41Å; Q145-M148 PolarHBondContact O-N 2.96Å; Q145-M148 VanDerWaalsContact O-N 3.17Å; W146-M148 PolarHBondContact O-N 3.49Å; M148-L152 VanDerWaalsContact O-CG 3.26Å; M148-L152 WeakPolarHBondContact O-CG 3.06Å; M148-L152 PolarHBondContact O-N 2.77Å; M148-L288 HydrophobicContact CE-CD1 3.62Å; M148-L288 HydrophobicContact CE-CG 3.71Å; M148-N290 WeakPolarHBondContact CA-OD1 3.38Å; M148-N290 HydrophobicContact CB-CB 4.24Å; M148-N290 WeakPolarHBondContact CB-ND2 3.06Å; M148-N290 HydrophobicContact CG-CB 3.98Å; M148-N290 PolarHBondContact O-ND2 2.88Å; M148-N290 VanDerWaalsContact O-ND2 3.16Å; M148-N290 HydrophobicContact SD-CB 4.06Å
149L98.8Very high98.2Very high0 Ų012.4 Ų12.40%06%0.061CC..Hα-helixtrans-66.6-41.5171.8-66.3157.5000111W73 I74 C77 Q145 W146 D147 N151 L152 I153 I263W73-L149 HydrophobicContact CD2-CD2 4.36Å; W73-L149 HydrophobicContact CE3-CD1 3.86Å; W73-L149 HydrophobicContact CE3-CD2 3.54Å; W73-L149 HydrophobicContact CE3-CG 3.4Å; W73-L149 HydrophobicContact CH2-CD2 4.45Å; W73-L149 HydrophobicContact CZ3-CB 4.49Å; W73-L149 HydrophobicContact CZ3-CD1 4.46Å; W73-L149 HydrophobicContact CZ3-CD2 3.58Å; W73-L149 HydrophobicContact CZ3-CG 3.52Å; I74-L149 HydrophobicContact CG1-CD2 3.98Å; C77-L149 HydrophobicContact CB-CD1 3.5Å; C77-L149 HydrophobicContact CB-CD2 4.01Å; C77-L149 HydrophobicContact CB-CG 4.29Å; Q145-L149 PolarHBondContact O-N 3.07Å; W146-L149 HydrophobicContact CE3-CD1 3.92Å; W146-L149 HydrophobicContact CZ3-CD1 4.32Å; W146-L149 WeakPolarHBondContact O-CA 3.32Å; W146-L149 VanDerWaalsContact O-CB 3.29Å; W146-L149 WeakPolarHBondContact O-CB 3.17Å; W146-L149 PolarHBondContact O-N 3.01Å; D147-L149 VanDerWaalsContact C-N 3.33Å; L149-N151 VanDerWaalsContact C-N 3.33Å; L149-N151 PolarHBondContact O-N 3.34Å; L149-L152 PolarHBondContact O-N 3.31Å; L149-I153 HydrophobicContact CB-CD1 4.46Å; L149-I153 WeakPolarHBondContact O-CB 3.39Å; L149-I153 WeakPolarHBondContact O-CG1 3.41Å; L149-I153 PolarHBondContact O-N 2.98Å; L149-I263 HydrophobicContact CB-CD1 4.18Å
150V98.8Very high98.3Very high1 Ų111.9 Ų11.91%0.0066%0.058CC..Hα-helixtrans-58.4-47.3176.4-178.60000110.3W146 D147 L152 I153 E154 I263 Q264 R295W146-V150 PolarHBondContact O-N 3.28Å; W146-V150 VanDerWaalsContact O-N 3.1Å; D147-V150 WeakPolarHBondContact O-CB 3.3Å; D147-V150 PolarHBondContact O-N 3.48Å; V150-L152 VanDerWaalsContact C-N 3.32Å; V150-L152 PolarHBondContact O-N 3.2Å; V150-I153 PolarHBondContact O-N 2.8Å; V150-E154 HydrophobicContact CG1-CG 4.08Å; V150-E154 VanDerWaalsContact O-CB 3.29Å; V150-E154 WeakPolarHBondContact O-CB 3.41Å; V150-E154 WeakPolarHBondContact O-CG 3.43Å; V150-E154 PolarHBondContact O-N 2.99Å; V150-I263 HydrophobicContact CG1-CG2 4.23Å; V150-I263 HydrophobicContact CG2-CD1 4.11Å; V150-I263 HydrophobicContact CG2-CG1 4Å; V150-I263 HydrophobicContact CG2-CG2 4.39Å; V150-Q264 HydrophobicContact CG1-CG 4.38Å; V150-R295 VanDerWaalsContact CG1-CD 3.48Å
151N98.9Very high98.5Very high12 Ų1214.2 Ų14.26%0.0647%0.068CC..Hα-helixtrans-55-48.3176.6-72-25.8000111.7D147 L149 K155 N290 M291 R295D147-N151 VanDerWaalsContact O-CG 3.3Å; D147-N151 PolarHBondContact O-N 2.8Å; D147-N151 PolarHBondContact O-ND2 2.81Å; L149-N151 VanDerWaalsContact C-N 3.33Å; L149-N151 PolarHBondContact O-N 3.34Å; N151-K155 VanDerWaalsContact O-CB 3.24Å; N151-K155 WeakPolarHBondContact O-CB 3.35Å; N151-K155 PolarHBondContact O-N 3Å; N151-N290 PolarHBondContact ND2-OD1 3.39Å; N151-M291 HydrophobicContact CB-CB 4.24Å; N151-M291 HydrophobicContact CB-CE 3.9Å; N151-M291 HydrophobicContact CB-SD 4.02Å; N151-M291 WeakPolarHBondContact O-CE 3.36Å; N151-R295 PolarHBondContact ND2-O 3.36Å; N151-R295 VanDerWaalsContact ND2-O 3.13Å; N151-R295 VanDerWaalsContact OD1-CB 3.29Å; N151-R295 WeakPolarHBondContact OD1-CB 3.42Å; N151-R295 PolarHBondContact OD1-N 3.07Å
152L98.9Very high98.6Very high0 Ų020.2 Ų20.20%09%0.092CC..Hα-helixtrans-68.5-47.9-177.5-65.7167.4000112.3W73 L101 W104 D105 M148 L149 V150 K155 Y156 N290 M291W73-L152 HydrophobicContact CH2-CD1 3.95Å; W73-L152 HydrophobicContact CZ3-CD1 4.44Å; L101-L152 HydrophobicContact CD2-CB 4.31Å; W104-L152 HydrophobicContact CB-CD2 3.93Å; D105-L152 HydrophobicContact CB-CD1 3.66Å; D105-L152 HydrophobicContact CB-CD2 4.31Å; M148-L152 VanDerWaalsContact O-CG 3.26Å; M148-L152 WeakPolarHBondContact O-CG 3.06Å; M148-L152 PolarHBondContact O-N 2.77Å; L149-L152 PolarHBondContact O-N 3.31Å; V150-L152 VanDerWaalsContact C-N 3.32Å; V150-L152 PolarHBondContact O-N 3.2Å; L152-K155 PolarHBondContact O-N 3.38Å; L152-Y156 HydrophobicContact CD2-CD2 4.3Å; L152-Y156 HydrophobicContact CD2-CE2 4.47Å; L152-Y156 WeakPolarHBondContact O-CA 3.47Å; L152-Y156 WeakPolarHBondContact O-CB 3.31Å; L152-Y156 PolarHBondContact O-N 3.33Å; L152-N290 WeakPolarHBondContact CG-ND2 3.48Å; L152-M291 HydrophobicContact CD2-CE 4.4Å
153I98.8Very high98.6Very high0 Ų021.7 Ų21.70%010%0.101CC..Hα-helixtrans-71-38.2-174.4-70.4168.1000111L81 L101 L149 V150 G157 V158 Y253 I263L81-I153 HydrophobicContact CD2-CD1 4.15Å; L101-I153 HydrophobicContact CD1-CD1 4.02Å; L101-I153 HydrophobicContact CD1-CG1 3.91Å; L101-I153 HydrophobicContact CD2-CG1 4.07Å; L149-I153 HydrophobicContact CB-CD1 4.46Å; L149-I153 WeakPolarHBondContact O-CB 3.39Å; L149-I153 WeakPolarHBondContact O-CG1 3.41Å; L149-I153 PolarHBondContact O-N 2.98Å; V150-I153 PolarHBondContact O-N 2.8Å; I153-G157 WeakPolarHBondContact O-CA 3.11Å; I153-G157 PolarHBondContact O-N 3.41Å; I153-V158 HydrophobicContact CD1-CG1 4.29Å; I153-V158 HydrophobicContact CG1-CG1 3.91Å; I153-V158 HydrophobicContact CG2-CG1 4.31Å; I153-Y253 HydrophobicContact CG2-CD1 4.23Å; I153-Y253 HydrophobicContact CG2-CD2 3.74Å; I153-Y253 HydrophobicContact CG2-CE1 3.94Å; I153-Y253 HydrophobicContact CG2-CE2 3.45Å; I153-Y253 VanDerWaalsContact CG2-CE2 3.45Å; I153-Y253 HydrophobicContact CG2-CG 4.15Å; I153-I263 HydrophobicContact CB-CD1 4.34Å; I153-I263 HydrophobicContact CD1-CD1 3.51Å; I153-I263 HydrophobicContact CG1-CD1 4.46Å; I153-I263 HydrophobicContact CG2-CG2 4.34Å
154E98.6Very high98.7Very high39 Ų3922 Ų2218%0.18210%0.102CC..Hα-helixtrans-69.3-34.9176.3-71-64.4152.100112.4V150 Y253 K258 I263 Q264V150-E154 HydrophobicContact CG1-CG 4.08Å; V150-E154 VanDerWaalsContact O-CB 3.29Å; V150-E154 WeakPolarHBondContact O-CB 3.41Å; V150-E154 WeakPolarHBondContact O-CG 3.43Å; V150-E154 PolarHBondContact O-N 2.99Å; E154-Y253 PolarHBondContact OE1-OH 3.31Å; E154-K258 IonicContact OE1-NZ 2.68Å; E154-K258 PolarHBondContact OE1-NZ 2.76Å; E154-K258 IonicContact OE2-NZ 2.75Å; E154-K258 PolarHBondContact OE2-NZ 2.93Å; E154-I263 HydrophobicContact CG-CG2 4.32Å; E154-Q264 VanDerWaalsContact CD-CD 3.49Å; E154-Q264 HydrophobicContact CG-CG 4.1Å; E154-Q264 VanDerWaalsContact OE1-CD 3.3Å; E154-Q264 VanDerWaalsContact OE1-CG 3.27Å; E154-Q264 WeakPolarHBondContact OE1-CG 3.36Å
155K98.7Very high98.7Very high89 Ų8925.7 Ų25.739%0.38713%0.125SC..Hα-helixtrans-83.5-38.5-180-173.1171.7-179.2-178.90113.5E108 N151 L152 Q250 M291E108-K155 WeakPolarHBondContact OE1-CE 3.43Å; E108-K155 IonicContact OE1-NZ 3.47Å; E108-K155 PolarHBondContact OE1-NZ 2.68Å; N151-K155 VanDerWaalsContact O-CB 3.24Å; N151-K155 WeakPolarHBondContact O-CB 3.35Å; N151-K155 PolarHBondContact O-N 3Å; L152-K155 PolarHBondContact O-N 3.38Å; K155-Q250 PolarHBondContact O-NE2 2.76Å; K155-M291 HydrophobicContact CB-CE 4.08Å; K155-M291 HydrophobicContact CD-CE 3.57Å; K155-M291 HydrophobicContact CD-SD 3.69Å; K155-M291 HydrophobicContact CG-CE 4.43Å
156Y98.8Very high98.7Very high32 Ų3227.3 Ų27.313%0.12513%0.133CC..Hα-helixtrans-117.6-8.2-170.7-61.8-72.8000113.7Y100 W104 E108 L152 P249 M291Y100-Y156 WeakPolarHBondContact CE1-O 3.47Å; Y100-Y156 PolarHBondContact OH-O 2.88Å; W104-Y156 HydrophobicContact CB-CD2 3.74Å; W104-Y156 HydrophobicContact CB-CE2 3.96Å; W104-Y156 HydrophobicContact CB-CG 4.09Å; W104-Y156 AromaticContact CD1-CD1 3.95Å; W104-Y156 AromaticContact CD1-CG 3.69Å; W104-Y156 AromaticContact CD2-CD1 3.43Å; W104-Y156 HydrophobicContact CD2-CD1 3.43Å; W104-Y156 VanDerWaalsContact CD2-CD1 3.43Å; W104-Y156 HydrophobicContact CD2-CD2 4.09Å; W104-Y156 AromaticContact CD2-CE1 3.42Å; W104-Y156 HydrophobicContact CD2-CE1 3.42Å; W104-Y156 VanDerWaalsContact CD2-CE1 3.42Å; W104-Y156 HydrophobicContact CD2-CE2 4.08Å; W104-Y156 AromaticContact CD2-CG 3.76Å; W104-Y156 HydrophobicContact CD2-CG 3.76Å; W104-Y156 AromaticContact CD2-CZ 3.74Å; W104-Y156 AromaticContact CE2-CD1 3.39Å; W104-Y156 AromaticContact CE2-CE1 3.67Å; W104-Y156 AromaticContact CE2-CG 3.98Å; W104-Y156 AromaticContact CE3-CD1 3.87Å; W104-Y156 HydrophobicContact CE3-CD1 3.87Å; W104-Y156 AromaticContact CE3-CE1 3.31Å; W104-Y156 HydrophobicContact CE3-CE1 3.31Å; W104-Y156 HydrophobicContact CE3-CE2 4.05Å; W104-Y156 HydrophobicContact CE3-CG 4.43Å; W104-Y156 AromaticContact CE3-CZ 3.39Å; W104-Y156 AromaticContact CG-CD1 3.8Å; W104-Y156 HydrophobicContact CG-CD1 3.8Å; W104-Y156 AromaticContact CG-CD2 3.74Å; W104-Y156 HydrophobicContact CG-CD2 3.74Å; W104-Y156 HydrophobicContact CG-CE1 4.12Å; W104-Y156 HydrophobicContact CG-CE2 4.07Å; W104-Y156 AromaticContact CG-CG 3.58Å; W104-Y156 HydrophobicContact CG-CG 3.58Å; W104-Y156 HydrophobicContact CH2-CD1 4.23Å; W104-Y156 AromaticContact CH2-CE1 3.77Å; W104-Y156 HydrophobicContact CH2-CE1 3.77Å; W104-Y156 AromaticContact CZ2-CD1 3.82Å; W104-Y156 HydrophobicContact CZ2-CD1 3.82Å; W104-Y156 AromaticContact CZ2-CE1 3.85Å; W104-Y156 HydrophobicContact CZ2-CE1 3.85Å; W104-Y156 HydrophobicContact CZ3-CD1 4.25Å; W104-Y156 AromaticContact CZ3-CE1 3.5Å; W104-Y156 HydrophobicContact CZ3-CE1 3.5Å; W104-Y156 AromaticContact CZ3-CZ 3.87Å; W104-Y156 AromaticContact NE1-CD1 3.69Å; W104-Y156 AromaticContact NE1-CG 3.89Å; E108-Y156 HydrophobicContact CG-CE2 3.95Å; E108-Y156 PolarHBondContact OE1-OH 3.44Å; L152-Y156 HydrophobicContact CD2-CD2 4.3Å; L152-Y156 HydrophobicContact CD2-CE2 4.47Å; L152-Y156 WeakPolarHBondContact O-CA 3.47Å; L152-Y156 WeakPolarHBondContact O-CB 3.31Å; L152-Y156 PolarHBondContact O-N 3.33Å; Y156-P249 WeakPolarHBondContact O-CB 3.09Å; Y156-M291 HydrophobicContact CE2-CE 4.01Å
157G98.7Very high98.7Very high0 Ų028.6 Ų28.60%014%0.142CC..  trans67.1-157.7-174.700000112.9L101 I153L101-G157 WeakPolarHBondContact CD2-O 3.49Å; I153-G157 WeakPolarHBondContact O-CA 3.11Å; I153-G157 PolarHBondContact O-N 3.41Å
158V98.8Very high98.7Very high1 Ų135.7 Ų35.71%0.00618%0.175CC..  trans-138.1160.9175.4-67.80000108.2L78 F96 L101 I153 F252 Y253 V257L78-V158 HydrophobicContact CD2-CG1 3.95Å; F96-V158 HydrophobicContact CD1-CB 4.11Å; F96-V158 HydrophobicContact CD1-CG2 3.95Å; F96-V158 HydrophobicContact CE1-CG2 3.89Å; F96-V158 HydrophobicContact CG-CB 4.49Å; F96-V158 HydrophobicContact CZ-CG2 4.43Å; L101-V158 HydrophobicContact CD1-CG1 4.38Å; L101-V158 HydrophobicContact CD2-CG1 4.43Å; I153-V158 HydrophobicContact CD1-CG1 4.29Å; I153-V158 HydrophobicContact CG1-CG1 3.91Å; I153-V158 HydrophobicContact CG2-CG1 4.31Å; V158-F252 HydrophobicContact CG2-CD1 4.22Å; V158-F252 HydrophobicContact CG2-CE1 4.15Å; V158-F252 WeakPolarHBondContact O-CD1 3.09Å; V158-Y253 HydrophobicContact CG2-CD2 4.19Å; V158-V257 HydrophobicContact CG2-CB 4.39Å; V158-V257 HydrophobicContact CG2-CG1 4.35Å; V158-V257 HydrophobicContact CG2-CG2 3.87Å
159I98.8Very high98.7Very high1 Ų136.5 Ų36.51%0.00518%0.18CC..  trans-140.2158176.459.6178.2000111F96 S97 Y100 C163 F164 P227 I230 P249F96-I159 CarbonylContact C-O 3.17Å; F96-I159 VanDerWaalsContact CA-O 3.3Å; F96-I159 WeakPolarHBondContact CA-O 3.35Å; S97-I159 PolarHBondContact N-O 3.37Å; Y100-I159 HydrophobicContact CD1-CD1 4.48Å; Y100-I159 HydrophobicContact CD1-CG1 4.15Å; Y100-I159 HydrophobicContact CD2-CD1 3.38Å; Y100-I159 HydrophobicContact CD2-CG1 3.94Å; Y100-I159 HydrophobicContact CE2-CD1 3.94Å; Y100-I159 HydrophobicContact CG-CD1 3.7Å; Y100-I159 HydrophobicContact CG-CG1 3.74Å; I159-C163 HydrophobicContact CD1-CB 4.46Å; I159-F164 HydrophobicContact CD1-CB 3.42Å; I159-F164 VanDerWaalsContact CD1-CB 3.42Å; I159-F164 HydrophobicContact CD1-CG 4.37Å; I159-F164 HydrophobicContact CG1-CB 4.41Å; I159-P227 HydrophobicContact CD1-CG 3.99Å; I159-I230 HydrophobicContact CB-CD1 4.17Å; I159-I230 HydrophobicContact CB-CG2 4.47Å; I159-I230 HydrophobicContact CG2-CD1 3.91Å; I159-I230 HydrophobicContact CG2-CG2 4.06Å; I159-P249 HydrophobicContact CG2-CB 3.58Å; I159-P249 HydrophobicContact CG2-CG 3.68Å
160P98.8Very high98.7Very high1 Ų136.5 Ų36.51%0.00618%0.18CC..BIsolated β-bridgetrans-58.9140.1170-24.736.5000111.8F94 K162 C163 I230 W232 F252F94-P160 HydrophobicContact CE2-CB 3.87Å; F94-P160 HydrophobicContact CE2-CG 4.07Å; F94-P160 HydrophobicContact CZ-CB 4.21Å; F94-P160 HydrophobicContact CZ-CG 4.25Å; P160-K162 PolarHBondContact O-N 3.21Å; P160-K162 VanDerWaalsContact O-N 3.12Å; P160-C163 WeakPolarHBondContact O-CB 3.45Å; P160-C163 PolarHBondContact O-N 3.49Å; P160-I230 HydrophobicContact CG-CD1 4.47Å; P160-W232 HydrophobicContact CB-CD2 3.97Å; P160-W232 HydrophobicContact CB-CG 3.92Å; P160-W232 HydrophobicContact CG-CB 3.98Å; P160-W232 HydrophobicContact CG-CD2 3.53Å; P160-W232 HydrophobicContact CG-CE3 3.83Å; P160-W232 HydrophobicContact CG-CG 3.58Å; P160-F252 HydrophobicContact CG-CE2 3.9Å; P160-F252 HydrophobicContact CG-CZ 3.77Å
161K98.8Very high98.7Very high49 Ų4939.9 Ų39.921%0.21320%0.196CC..G310 helixtrans-55.2-32178.6-173.1175-177.71780113.3E95 C163 F164 P165E95-K161 HydrophobicContact CB-CB 3.84Å; E95-K161 HydrophobicContact CB-CD 3.67Å; E95-K161 HydrophobicContact CB-CG 4.43Å; E95-K161 VanDerWaalsContact CD-CD 3.5Å; E95-K161 HydrophobicContact CG-CD 4.22Å; E95-K161 WeakPolarHBondContact O-CB 3.47Å; E95-K161 PolarHBondContact O-N 2.84Å; E95-K161 IonicContact OE1-NZ 2.85Å; E95-K161 PolarHBondContact OE1-NZ 2.92Å; E95-K161 WeakPolarHBondContact OE2-CD 3.49Å; E95-K161 IonicContact OE2-NZ 3.64Å; E95-K161 PolarHBondContact OE2-NZ 3.43Å; K161-C163 PolarHBondContact O-N 3.35Å; K161-F164 CarbonylContact O-C 3.53Å; K161-F164 PolarHBondContact O-N 3.13Å; K161-P165 WeakPolarHBondContact O-CA 3.3Å
162K98.3Very high98.7Very high179 Ų17940.7 Ų40.778%0.77820%0.204SC*.G310 helixtrans-66.6-20.4176.9-64.4-173.7179.9179.60113.7P160P160-K162 PolarHBondContact O-N 3.21Å; P160-K162 VanDerWaalsContact O-N 3.12Å
163C98.6Very high98.7Very high35 Ų3541 Ų4124%0.23621%0.206CC..G310 helixtrans-89.4-18.4178.2-61.40000113I159 P160 K161 I230I159-C163 HydrophobicContact CD1-CB 4.46Å; P160-C163 WeakPolarHBondContact O-CB 3.45Å; P160-C163 PolarHBondContact O-N 3.49Å; K161-C163 PolarHBondContact O-N 3.35Å; C163-I230 HydrophobicContact CB-CB 4.28Å; C163-I230 HydrophobicContact CB-CG2 3.78Å
164F98.8Very high98.7Very high12 Ų1249.4 Ų49.45%0.05324%0.238CC..SBendtrans-150.694172-168.5-108.2000108.5S97 S99 I159 K161 L223 S225 P226S97-F164 WeakPolarHBondContact CB-O 3.44Å; S97-F164 PolarHBondContact OG-O 3.36Å; S99-F164 VanDerWaalsContact OG-CD1 3.3Å; S99-F164 WeakPolarHBondContact OG-CD1 3.42Å; S99-F164 PolarHBondContact OG-O 2.73Å; I159-F164 HydrophobicContact CD1-CB 3.42Å; I159-F164 VanDerWaalsContact CD1-CB 3.42Å; I159-F164 HydrophobicContact CD1-CG 4.37Å; I159-F164 HydrophobicContact CG1-CB 4.41Å; K161-F164 CarbonylContact O-C 3.53Å; K161-F164 PolarHBondContact O-N 3.13Å; F164-L223 VanDerWaalsContact CZ-O 3.27Å; F164-L223 WeakPolarHBondContact CZ-O 3.23Å; F164-S225 WeakPolarHBondContact CE2-O 3.47Å; F164-P226 HydrophobicContact CZ-CG 4.48Å
165P98.7Very high98.7Very high81 Ų8155.7 Ų55.753%0.52626%0.26SS..  trans-75.2176.7-171.631.8-36.3000112.3S99 K161S99-P165 PolarHBondContact OG-O 3.48Å; K161-P165 WeakPolarHBondContact O-CA 3.3Å
166E98.8Very high98.7Very high35 Ų3551.5 Ų51.516%0.16424%0.242CC..  trans-67.9152.8167.5-68.9-69.4123.900110.9R71 S99 S170 E171R71-E166 IonicContact CZ-OE1 2.8Å; R71-E166 IonicContact CZ-OE2 3.79Å; R71-E166 VanDerWaalsContact CZ-OE2 3.23Å; R71-E166 VanDerWaalsContact NH1-CD 3.31Å; R71-E166 IonicContact NH1-OE1 3.12Å; R71-E166 PolarHBondContact NH1-OE1 3.31Å; R71-E166 IonicContact NH1-OE2 2.97Å; R71-E166 PolarHBondContact NH1-OE2 2.88Å; R71-E166 IonicContact NH2-OE1 2.64Å; R71-E166 IonicContact NH2-OE2 3.78Å; R71-E166 PolarHBondContact NH2-OE2 3.5Å; S99-E166 WeakPolarHBondContact CB-OE1 3.15Å; S99-E166 PolarHBondContact N-OE1 3.39Å; E166-S170 WeakPolarHBondContact CA-OG 3.16Å; E166-S170 VanDerWaalsContact CD-OG 3.28Å; E166-S170 VanDerWaalsContact OE2-CB 3.27Å; E166-S170 WeakPolarHBondContact OE2-CB 3.48Å; E166-S170 PolarHBondContact OE2-OG 2.81Å; E166-E171 HydrophobicContact CB-CG 4.16Å; E166-E171 HydrophobicContact CG-CG 4.41Å
167S98.8Very high98.7Very high29 Ų2950.7 Ų50.720%0.20324%0.24CC..  trans-118.3171.3171.966.50000109.4S169 S170 E171 C222S167-S169 PolarHBondContact O-N 2.97Å; S167-S169 PolarHBondContact OG-N 3.46Å; S167-S170 PolarHBondContact N-OG 3.41Å; S167-S170 PolarHBondContact O-N 3.03Å; S167-S170 PolarHBondContact O-OG 3.3Å; S167-S170 PolarHBondContact OG-N 2.99Å; S167-S170 VanDerWaalsContact OG-N 3.09Å; S167-S170 PolarHBondContact OG-OG 3.35Å; S167-E171 PolarHBondContact O-N 3.02Å; S167-C222 PolarHBondContact OG-O 3.23Å
168H98.7Very high98.7Very high153 Ų15354.1 Ų54.171%0.70826%0.258SS*.Hα-helixtrans-55.8-43.4172.1-178.277.2000111.9S170 E171 A172H168-S170 PolarHBondContact O-N 3.01Å; H168-E171 PolarHBondContact O-N 3.34Å; H168-A172 PolarHBondContact O-N 3.13Å
169S98.6Very high98.7Very high18 Ų1858.2 Ų58.213%0.12628%0.279CS..Hα-helixtrans-74.3-25.7-176.2-47.80000112.8S167 A172 S173 C222S167-S169 PolarHBondContact O-N 2.97Å; S167-S169 PolarHBondContact OG-N 3.46Å; S169-A172 CarbonylContact O-C 3.27Å; S169-S173 WeakPolarHBondContact O-CA 3.49Å; S169-S173 PolarHBondContact O-N 2.81Å; S169-S173 VanDerWaalsContact O-N 3.17Å; S169-C222 WeakPolarHBondContact CB-O 3.46Å; S169-C222 WeakPolarHBondContact OG-CB 3.4Å; S169-C222 PolarHBondContact OG-O 3.45Å; S169-C222 VanDerWaalsContact OG-O 3.12Å
170S98.6Very high98.7Very high0 Ų058.2 Ų58.20%028%0.279CS..Hα-helixtrans-72.6-32.9173.666.40000111.4S69 R71 E166 S167 H168S69-S170 WeakPolarHBondContact CB-O 3.2Å; S69-S170 PolarHBondContact OG-O 2.84Å; R71-S170 PolarHBondContact NE-O 3.03Å; R71-S170 VanDerWaalsContact NE-O 3.12Å; R71-S170 PolarHBondContact NH2-O 3.49Å; E166-S170 WeakPolarHBondContact CA-OG 3.16Å; E166-S170 VanDerWaalsContact CD-OG 3.28Å; E166-S170 VanDerWaalsContact OE2-CB 3.27Å; E166-S170 WeakPolarHBondContact OE2-CB 3.48Å; E166-S170 PolarHBondContact OE2-OG 2.81Å; S167-S170 PolarHBondContact N-OG 3.41Å; S167-S170 PolarHBondContact O-N 3.03Å; S167-S170 PolarHBondContact O-OG 3.3Å; S167-S170 PolarHBondContact OG-N 2.99Å; S167-S170 VanDerWaalsContact OG-N 3.09Å; S167-S170 PolarHBondContact OG-OG 3.35Å; H168-S170 PolarHBondContact O-N 3.01Å
171E98.7Very high98.7Very high72 Ų7258.7 Ų58.734%0.33628%0.282SS..Hα-helixtrans-87.5-12.4175.6-65.3-169.3160.500114.4K67 N68 E166 S167 H168K67-E171 HydrophobicContact CB-CB 3.83Å; K67-E171 HydrophobicContact CB-CG 4.25Å; K67-E171 VanDerWaalsContact CB-O 3.3Å; K67-E171 WeakPolarHBondContact CB-O 3.11Å; K67-E171 HydrophobicContact CG-CB 4Å; K67-E171 HydrophobicContact CG-CG 3.98Å; N68-E171 CarbonylContact C-O 3.49Å; N68-E171 WeakPolarHBondContact CA-O 3.4Å; N68-E171 WeakPolarHBondContact CB-O 3.17Å; N68-E171 PolarHBondContact N-O 2.94Å; E166-E171 HydrophobicContact CB-CG 4.16Å; E166-E171 HydrophobicContact CG-CG 4.41Å; S167-E171 PolarHBondContact O-N 3.02Å; H168-E171 PolarHBondContact O-N 3.34Å
172A98.7Very high98.7Very high28 Ų2862.2 Ų62.223%0.23130%0.299CS..BIsolated β-bridgetrans-147.369.6178.900000111.7N68 H168 S169 R174N68-A172 WeakPolarHBondContact O-CA 3.3Å; H168-A172 PolarHBondContact O-N 3.13Å; S169-A172 CarbonylContact O-C 3.27Å; A172-R174 VanDerWaalsContact C-N 3.3Å; A172-R174 PolarHBondContact O-N 2.93Å
173S98.6Very high98.7Very high7 Ų755.6 Ų55.65%0.04927%0.27CS..THydrogen-bonded Turntrans-70.9-16.9-16659.50000115.8N68 D142 S169 R175 M176 N177N68-S173 PolarHBondContact O-N 2.95Å; D142-S173 WeakPolarHBondContact OD2-CB 3.4Å; D142-S173 PolarHBondContact OD2-OG 2.83Å; S169-S173 WeakPolarHBondContact O-CA 3.49Å; S169-S173 PolarHBondContact O-N 2.81Å; S169-S173 VanDerWaalsContact O-N 3.17Å; S173-R175 VanDerWaalsContact C-N 3.29Å; S173-R175 PolarHBondContact O-N 3.48Å; S173-R175 VanDerWaalsContact O-N 3.11Å; S173-M176 PolarHBondContact O-N 3.03Å; S173-M176 VanDerWaalsContact O-N 3.14Å; S173-N177 PolarHBondContact O-N 2.84Å
174R98.6Very high98.7Very high176 Ų17654 Ų5466%0.66426%0.259SS*.Hα-helixtrans-47-47.6-174-178.6178.3176.6176.93.8113.3A172 N177 D178A172-R174 VanDerWaalsContact C-N 3.3Å; A172-R174 PolarHBondContact O-N 2.93Å; R174-N177 PolarHBondContact O-N 3.4Å; R174-D178 WeakPolarHBondContact O-CB 3.29Å; R174-D178 PolarHBondContact O-N 3.01Å
175R98.6Very high98.7Very high171 Ų17158.6 Ų58.665%0.64528%0.276SS*.Hα-helixtrans-70.4-40.2-174.9-63.1-55.1-171.5-176.65.1113.1S173 D178 I179S173-R175 VanDerWaalsContact C-N 3.29Å; S173-R175 PolarHBondContact O-N 3.48Å; S173-R175 VanDerWaalsContact O-N 3.11Å; R175-D178 IonicContact NH1-OD2 2.78Å; R175-D178 PolarHBondContact O-N 2.67Å; R175-I179 WeakPolarHBondContact O-CG1 3.25Å; R175-I179 PolarHBondContact O-N 3.1Å
176M98.8Very high98.7Very high2 Ų259 Ų591%0.0127%0.271CS..Hα-helixtrans-63.2-45.6173.5-178.6-174.27000110.3F102 K106 S173 D178 I179 L180 V218 C222 L223F102-M176 HydrophobicContact CE1-CE 3.6Å; F102-M176 HydrophobicContact CZ-CE 3.69Å; K106-M176 HydrophobicContact CG-CE 4.39Å; S173-M176 PolarHBondContact O-N 3.03Å; S173-M176 VanDerWaalsContact O-N 3.14Å; M176-D178 PolarHBondContact O-N 3.34Å; M176-I179 PolarHBondContact O-N 3.37Å; M176-L180 HydrophobicContact CG-CD1 3.98Å; M176-L180 HydrophobicContact CG-CG 4.49Å; M176-L180 WeakPolarHBondContact O-CG 3.46Å; M176-L180 PolarHBondContact O-N 3.4Å; M176-V218 HydrophobicContact CG-CG1 4.39Å; M176-C222 HydrophobicContact CB-CB 4.34Å; M176-C222 HydrophobicContact CG-CB 3.89Å; M176-C222 HydrophobicContact SD-CB 3.54Å; M176-C222 VanDerWaalsContact SD-CB 3.54Å; M176-L223 HydrophobicContact CE-CD1 4.33Å; M176-L223 HydrophobicContact CE-CD2 4.46Å; M176-L223 HydrophobicContact SD-CD1 4.01Å; M176-L223 HydrophobicContact SD-CD2 4.09Å; M176-L223 HydrophobicContact SD-CG 3.9Å
177N98.8Very high98.7Very high14 Ų1457.4 Ų57.48%0.07526%0.263CS..Hα-helixtrans-64-38.6178.2-72.2-19.1000112.4K106 T140 D142 S173 R174 I179 L180 N181K106-N177 WeakPolarHBondContact CE-OD1 3.47Å; K106-N177 PolarHBondContact NZ-OD1 2.96Å; T140-N177 PolarHBondContact O-OD1 2.79Å; T140-N177 PolarHBondContact OG1-O 3.31Å; D142-N177 PolarHBondContact OD1-ND2 2.98Å; D142-N177 PolarHBondContact OD1-OD1 2.77Å; S173-N177 PolarHBondContact O-N 2.84Å; R174-N177 PolarHBondContact O-N 3.4Å; N177-I179 VanDerWaalsContact C-N 3.32Å; N177-I179 PolarHBondContact O-N 3.23Å; N177-L180 PolarHBondContact O-N 2.99Å; N177-N181 WeakPolarHBondContact O-CB 3.21Å; N177-N181 VanDerWaalsContact O-CG 3.24Å; N177-N181 PolarHBondContact O-N 3.31Å; N177-N181 PolarHBondContact O-ND2 3.46Å
178D98.8Very high98.7Very high72 Ų7256.2 Ų56.239%0.38526%0.255SS..Hα-helixtrans-58.7-44175.4-72.2-22.9000111.3R174 R175 M176 H182R174-D178 WeakPolarHBondContact O-CB 3.29Å; R174-D178 PolarHBondContact O-N 3.01Å; R175-D178 IonicContact NH1-OD2 2.78Å; R175-D178 PolarHBondContact O-N 2.67Å; M176-D178 PolarHBondContact O-N 3.34Å; D178-H182 WeakPolarHBondContact O-CB 3.14Å; D178-H182 PolarHBondContact O-N 3.21Å; D178-H182 VanDerWaalsContact O-N 3.1Å
179I98.8Very high98.8Very high87 Ų8754 Ų5445%0.44625%0.248SC..Hα-helixtrans-65.8-49.7178.2-66165.9000110.7R175 M176 N177 H182 K183 V218R175-I179 WeakPolarHBondContact O-CG1 3.25Å; R175-I179 PolarHBondContact O-N 3.1Å; M176-I179 PolarHBondContact O-N 3.37Å; N177-I179 VanDerWaalsContact C-N 3.32Å; N177-I179 PolarHBondContact O-N 3.23Å; I179-H182 WeakPolarHBondContact O-CB 3.26Å; I179-H182 PolarHBondContact O-N 3.01Å; I179-K183 PolarHBondContact O-N 3.45Å; I179-K183 VanDerWaalsContact O-N 3.11Å; I179-V218 HydrophobicContact CG2-CG1 4.1Å; I179-V218 HydrophobicContact CG2-CG2 4.22Å
180L98.8Very high98.8Very high1 Ų158.8 Ų58.81%0.00526%0.263CS..Hα-helixtrans-65-44.3-179.1-67.2172.9000111.6K106 T140 M176 N177 H182 K183 L184 V215 V218K106-L180 HydrophobicContact CD-CD1 3.75Å; K106-L180 HydrophobicContact CG-CD1 3.58Å; T140-L180 HydrophobicContact CG2-CB 3.48Å; T140-L180 VanDerWaalsContact CG2-CB 3.48Å; T140-L180 HydrophobicContact CG2-CD1 4.3Å; M176-L180 HydrophobicContact CG-CD1 3.98Å; M176-L180 HydrophobicContact CG-CG 4.49Å; M176-L180 WeakPolarHBondContact O-CG 3.46Å; M176-L180 PolarHBondContact O-N 3.4Å; N177-L180 PolarHBondContact O-N 2.99Å; L180-H182 VanDerWaalsContact C-N 3.26Å; L180-H182 PolarHBondContact O-N 2.77Å; L180-K183 PolarHBondContact O-N 2.71Å; L180-K183 VanDerWaalsContact O-N 3.17Å; L180-L184 WeakPolarHBondContact O-CB 3.48Å; L180-L184 WeakPolarHBondContact O-CG 3.13Å; L180-L184 PolarHBondContact O-N 2.87Å; L180-V215 HydrophobicContact CD2-CB 4.43Å; L180-V215 HydrophobicContact CD2-CG1 4.06Å; L180-V215 HydrophobicContact CD2-CG2 4.4Å; L180-V218 HydrophobicContact CD2-CB 3.81Å; L180-V218 HydrophobicContact CD2-CG1 3.7Å; L180-V218 HydrophobicContact CD2-CG2 4.41Å; L180-V218 HydrophobicContact CG-CG1 3.98Å
181N98.8Very high98.8Very high11 Ų1158.8 Ų58.86%0.05926%0.263CS..Hα-helixtrans-57.5-39.5175.2-81.4-31.3000111.9N138 P139 T140 N177 R185N138-N181 PolarHBondContact OD1-ND2 3.4Å; P139-N181 WeakPolarHBondContact CD-OD1 3.4Å; P139-N181 WeakPolarHBondContact CG-OD1 3.18Å; T140-N181 PolarHBondContact N-OD1 3.12Å; T140-N181 PolarHBondContact OG1-ND2 3.4Å; T140-N181 PolarHBondContact OG1-OD1 2.91Å; N177-N181 WeakPolarHBondContact O-CB 3.21Å; N177-N181 VanDerWaalsContact O-CG 3.24Å; N177-N181 PolarHBondContact O-N 3.31Å; N177-N181 PolarHBondContact O-ND2 3.46Å; N181-R185 WeakPolarHBondContact O-CD 3.4Å; N181-R185 VanDerWaalsContact O-CG 3.23Å; N181-R185 WeakPolarHBondContact O-CG 3.33Å; N181-R185 PolarHBondContact O-N 3.22Å; N181-R185 VanDerWaalsContact O-N 3.13Å
182H98.8Very high98.8Very high124 Ų12457.4 Ų57.457%0.57426%0.255SS*.Hα-helixtrans-61-51.7174.718086.1000111.5D178 I179 L180 L184 R185 E186D178-H182 WeakPolarHBondContact O-CB 3.14Å; D178-H182 PolarHBondContact O-N 3.21Å; D178-H182 VanDerWaalsContact O-N 3.1Å; I179-H182 WeakPolarHBondContact O-CB 3.26Å; I179-H182 PolarHBondContact O-N 3.01Å; L180-H182 VanDerWaalsContact C-N 3.26Å; L180-H182 PolarHBondContact O-N 2.77Å; H182-L184 PolarHBondContact O-N 3.28Å; H182-R185 PolarHBondContact O-N 3.45Å; H182-E186 PolarHBondContact O-N 2.88Å; H182-E186 VanDerWaalsContact O-N 3.11Å
183K98.8Very high98.8Very high40 Ų4060.3 Ų60.317%0.17427%0.267CS..Hα-helixtrans-62.7-41.6178.9-70.3-59.3-56.3179.80112.6I179 L180 R185 E186 Y187 E214I179-K183 PolarHBondContact O-N 3.45Å; I179-K183 VanDerWaalsContact O-N 3.11Å; L180-K183 PolarHBondContact O-N 2.71Å; L180-K183 VanDerWaalsContact O-N 3.17Å; K183-R185 VanDerWaalsContact C-N 3.31Å; K183-R185 PolarHBondContact O-N 2.75Å; K183-E186 WeakPolarHBondContact CE-OE2 3.49Å; K183-E186 VanDerWaalsContact NZ-CD 3.25Å; K183-E186 IonicContact NZ-OE1 3Å; K183-E186 PolarHBondContact NZ-OE1 3.29Å; K183-E186 IonicContact NZ-OE2 2.69Å; K183-E186 PolarHBondContact NZ-OE2 3.48Å; K183-E186 WeakPolarHBondContact O-CB 3.49Å; K183-E186 PolarHBondContact O-N 2.86Å; K183-Y187 HydrophobicContact CB-CE2 4.06Å; K183-Y187 VanDerWaalsContact CE-CE1 3.46Å; K183-Y187 WeakPolarHBondContact CE-OH 3.4Å; K183-Y187 WeakPolarHBondContact O-CB 3.36Å; K183-Y187 WeakPolarHBondContact O-CD1 3.47Å; K183-Y187 WeakPolarHBondContact O-CD2 3.25Å; K183-Y187 PolarHBondContact O-N 3.31Å; K183-E214 WeakPolarHBondContact CE-OE2 3.49Å; K183-E214 IonicContact NZ-OE2 2.85Å; K183-E214 PolarHBondContact NZ-OE2 2.92Å
184L98.8Very high98.8Very high0 Ų061.8 Ų61.80%027%0.273CS..Hα-helixtrans-64.3-34.8178-70.5-172.8000112.8C110 F113 L114 P139 T140 L180 H182 Y187 C188 V215C110-L184 HydrophobicContact CB-CD1 4.36Å; C110-L184 HydrophobicContact CB-CD2 4.1Å; F113-L184 HydrophobicContact CD1-CB 4.01Å; F113-L184 HydrophobicContact CD1-CD1 3.96Å; F113-L184 HydrophobicContact CD1-CD2 4.1Å; F113-L184 HydrophobicContact CD1-CG 4.26Å; F113-L184 HydrophobicContact CE1-CB 3.79Å; F113-L184 HydrophobicContact CE1-CD1 4.48Å; F113-L184 HydrophobicContact CG-CD1 4.42Å; L114-L184 HydrophobicContact CD2-CD2 4.05Å; L114-L184 HydrophobicContact CG-CD2 4.39Å; P139-L184 HydrophobicContact CB-CB 4.45Å; P139-L184 HydrophobicContact CB-CD1 3.71Å; P139-L184 HydrophobicContact CG-CB 4Å; P139-L184 HydrophobicContact CG-CD1 3.9Å; T140-L184 HydrophobicContact CG2-CD1 3.41Å; T140-L184 VanDerWaalsContact CG2-CD1 3.41Å; T140-L184 HydrophobicContact CG2-CG 4.36Å; L180-L184 WeakPolarHBondContact O-CB 3.48Å; L180-L184 WeakPolarHBondContact O-CG 3.13Å; L180-L184 PolarHBondContact O-N 2.87Å; H182-L184 PolarHBondContact O-N 3.28Å; L184-Y187 HydrophobicContact CD2-CD2 4.08Å; L184-Y187 PolarHBondContact O-N 3.28Å; L184-C188 WeakPolarHBondContact O-CB 3.44Å; L184-C188 PolarHBondContact O-N 2.95Å; L184-V215 HydrophobicContact CD2-CG2 4.41Å
185R98.9Very high98.8Very high110 Ų11054.5 Ų54.542%0.41525%0.248SC..Hα-helixtrans-68.2-41173.7-70.6164.8179.6150.80.8111.8L136 S137 N181 H182 K183 Y187 C188 L189L136-R185 HydrophobicContact CD2-CB 4.36Å; L136-R185 HydrophobicContact CD2-CG 3.83Å; L136-R185 PolarHBondContact O-NE 3.15Å; L136-R185 PolarHBondContact O-NH2 2.88Å; S137-R185 PolarHBondContact O-NH2 2.67Å; N181-R185 WeakPolarHBondContact O-CD 3.4Å; N181-R185 VanDerWaalsContact O-CG 3.23Å; N181-R185 WeakPolarHBondContact O-CG 3.33Å; N181-R185 PolarHBondContact O-N 3.22Å; N181-R185 VanDerWaalsContact O-N 3.13Å; H182-R185 PolarHBondContact O-N 3.45Å; K183-R185 VanDerWaalsContact C-N 3.31Å; K183-R185 PolarHBondContact O-N 2.75Å; R185-Y187 VanDerWaalsContact C-N 3.33Å; R185-C188 PolarHBondContact O-N 3.4Å; R185-L189 PolarHBondContact O-N 3.1Å
186E98.9Very high98.8Very high88 Ų8850.2 Ų50.241%0.41125%0.249SC..Hα-helixtrans-59.2-44.6171.6-175.9-163.8141.100111.3H182 K183 L189 R190H182-E186 PolarHBondContact O-N 2.88Å; H182-E186 VanDerWaalsContact O-N 3.11Å; K183-E186 WeakPolarHBondContact CE-OE2 3.49Å; K183-E186 VanDerWaalsContact NZ-CD 3.25Å; K183-E186 IonicContact NZ-OE1 3Å; K183-E186 PolarHBondContact NZ-OE1 3.29Å; K183-E186 IonicContact NZ-OE2 2.69Å; K183-E186 PolarHBondContact NZ-OE2 3.48Å; K183-E186 WeakPolarHBondContact O-CB 3.49Å; K183-E186 PolarHBondContact O-N 2.86Å; E186-L189 WeakPolarHBondContact O-CB 3.19Å; E186-L189 PolarHBondContact O-N 2.8Å; E186-R190 PolarHBondContact O-N 3.11Å; E186-R190 VanDerWaalsContact O-N 3.07Å
187Y98.9Very high98.7Very high2 Ų254.7 Ų54.71%0.00828%0.28CS..Hα-helixtrans-67.4-38.5178.8-62.1-18.2000112.9L114 K183 L184 R185 L189 R190 L191 M211 E214 V215L114-Y187 HydrophobicContact CD2-CD2 3.9Å; L114-Y187 HydrophobicContact CD2-CG 4.21Å; K183-Y187 HydrophobicContact CB-CE2 4.06Å; K183-Y187 VanDerWaalsContact CE-CE1 3.46Å; K183-Y187 WeakPolarHBondContact CE-OH 3.4Å; K183-Y187 WeakPolarHBondContact O-CB 3.36Å; K183-Y187 WeakPolarHBondContact O-CD1 3.47Å; K183-Y187 WeakPolarHBondContact O-CD2 3.25Å; K183-Y187 PolarHBondContact O-N 3.31Å; L184-Y187 HydrophobicContact CD2-CD2 4.08Å; L184-Y187 PolarHBondContact O-N 3.28Å; R185-Y187 VanDerWaalsContact C-N 3.33Å; Y187-L189 VanDerWaalsContact C-N 3.32Å; Y187-L189 PolarHBondContact O-N 3.13Å; Y187-R190 PolarHBondContact O-N 2.86Å; Y187-L191 WeakPolarHBondContact O-CB 3.35Å; Y187-L191 VanDerWaalsContact O-CG 3.31Å; Y187-L191 WeakPolarHBondContact O-CG 3.46Å; Y187-L191 PolarHBondContact O-N 3.15Å; Y187-M211 HydrophobicContact CD1-CB 4.43Å; Y187-M211 HydrophobicContact CD1-CE 4.11Å; Y187-M211 HydrophobicContact CD1-CG 3.67Å; Y187-M211 HydrophobicContact CD1-SD 4.07Å; Y187-M211 HydrophobicContact CD2-CB 3.7Å; Y187-M211 HydrophobicContact CD2-CG 3.79Å; Y187-M211 HydrophobicContact CD2-SD 4.19Å; Y187-M211 HydrophobicContact CE1-CB 4.37Å; Y187-M211 HydrophobicContact CE1-CG 3.82Å; Y187-M211 HydrophobicContact CE2-CB 3.62Å; Y187-M211 HydrophobicContact CE2-CG 3.93Å; Y187-M211 HydrophobicContact CG-CB 4.11Å; Y187-M211 HydrophobicContact CG-CE 4.26Å; Y187-M211 HydrophobicContact CG-CG 3.65Å; Y187-M211 HydrophobicContact CG-SD 3.72Å; Y187-E214 WeakPolarHBondContact OH-CB 3.37Å; Y187-E214 PolarHBondContact OH-OE2 3.22Å; Y187-V215 HydrophobicContact CE2-CG2 4.34Å
188C98.9Very high98.7Very high4 Ų461 Ų613%0.02731%0.314CS..Hα-helixtrans-56.5-47.9173.1-176.30000111F113 C117 L136 L184 R185 R190 L191 R192F113-C188 HydrophobicContact CE1-CB 4.42Å; F113-C188 HydrophobicContact CZ-CB 4.44Å; C117-C188 HydrophobicContact CB-CB 4.47Å; C117-C188 VanDerWaalsContact SG-CB 3.59Å; C117-C188 PolarHBondContact SG-SG 3.02Å; L136-C188 HydrophobicContact CD2-CB 3.77Å; L184-C188 WeakPolarHBondContact O-CB 3.44Å; L184-C188 PolarHBondContact O-N 2.95Å; R185-C188 PolarHBondContact O-N 3.4Å; C188-R190 PolarHBondContact O-N 3.28Å; C188-L191 PolarHBondContact O-N 3.19Å; C188-R192 VanDerWaalsContact O-CB 3.31Å; C188-R192 WeakPolarHBondContact O-CB 3.3Å; C188-R192 WeakPolarHBondContact O-CG 3.11Å; C188-R192 PolarHBondContact O-N 3.28Å
189L98.8Very high98.7Very high107 Ų10758.7 Ų58.756%0.5631%0.306SS*.Hα-helixtrans-57-49.8175.2172.964.1000111.4R185 E186 Y187 R192 N193R185-L189 PolarHBondContact O-N 3.1Å; E186-L189 WeakPolarHBondContact O-CB 3.19Å; E186-L189 PolarHBondContact O-N 2.8Å; Y187-L189 VanDerWaalsContact C-N 3.32Å; Y187-L189 PolarHBondContact O-N 3.13Å; L189-R192 PolarHBondContact O-N 3.14Å; L189-N193 VanDerWaalsContact O-CG 3.29Å; L189-N193 PolarHBondContact O-N 3.21Å
190R98.8Very high98.6Very high118 Ų11858.1 Ų58.145%0.44531%0.306SS..Hα-helixtrans-61.6-48.9-178.8-179171.7165-161.8-2.3112.2E186 Y187 C188 R192 N193 M194 M211E186-R190 PolarHBondContact O-N 3.11Å; E186-R190 VanDerWaalsContact O-N 3.07Å; Y187-R190 PolarHBondContact O-N 2.86Å; C188-R190 PolarHBondContact O-N 3.28Å; R190-R192 VanDerWaalsContact C-N 3.34Å; R190-R192 PolarHBondContact O-N 2.96Å; R190-N193 PolarHBondContact O-N 3.28Å; R190-M194 HydrophobicContact CG-SD 4.26Å; R190-M194 WeakPolarHBondContact O-CG 3.36Å; R190-M194 PolarHBondContact O-N 3.23Å; R190-M211 HydrophobicContact CB-CE 4.05Å; R190-M211 HydrophobicContact CG-CE 3.87Å
191L98.9Very high98.5Very high0 Ų066.6 Ų66.60%034%0.343CS..Hα-helixtrans-62.9-40.8179.7-70.1171.5000111.7L114 C117 V118 Y187 C188 N193 M194 V195 L204 I208 M211L114-L191 HydrophobicContact CB-CD1 4.01Å; L114-L191 HydrophobicContact CD2-CD1 3.78Å; L114-L191 HydrophobicContact CG-CD1 4.47Å; C117-L191 HydrophobicContact CB-CD1 4.12Å; V118-L191 HydrophobicContact CG2-CB 4.22Å; V118-L191 HydrophobicContact CG2-CD1 4.21Å; V118-L191 HydrophobicContact CG2-CD2 4.11Å; V118-L191 HydrophobicContact CG2-CG 4.41Å; Y187-L191 WeakPolarHBondContact O-CB 3.35Å; Y187-L191 VanDerWaalsContact O-CG 3.31Å; Y187-L191 WeakPolarHBondContact O-CG 3.46Å; Y187-L191 PolarHBondContact O-N 3.15Å; C188-L191 PolarHBondContact O-N 3.19Å; L191-N193 PolarHBondContact O-N 2.83Å; L191-M194 HydrophobicContact CD2-SD 4.48Å; L191-M194 WeakPolarHBondContact O-CB 3.36Å; L191-M194 PolarHBondContact O-N 2.94Å; L191-V195 WeakPolarHBondContact O-CG2 3.44Å; L191-V195 PolarHBondContact O-N 3.29Å; L191-L204 HydrophobicContact CD2-CD2 4.29Å; L191-I208 HydrophobicContact CD1-CG1 4.34Å; L191-I208 HydrophobicContact CD2-CG1 3.89Å; L191-M211 HydrophobicContact CD1-SD 4.01Å; L191-M211 HydrophobicContact CD2-CE 4.01Å; L191-M211 HydrophobicContact CD2-SD 4.04Å; L191-M211 HydrophobicContact CG-CE 3.95Å; L191-M211 HydrophobicContact CG-SD 3.95Å
192R98.8Very high98.5Very high43 Ų4370.5 Ų70.516%0.16237%0.367CS..Hα-helixtrans-63.2-41.5175.7-71.1177.967.279.25.9112A121 E125 C188 L189 R190 M194 V195 A196A121-R192 HydrophobicContact CB-CB 4.42Å; A121-R192 HydrophobicContact CB-CG 3.92Å; E125-R192 PolarHBondContact O-NH1 3.03Å; E125-R192 PolarHBondContact O-NH2 3.23Å; C188-R192 VanDerWaalsContact O-CB 3.31Å; C188-R192 WeakPolarHBondContact O-CB 3.3Å; C188-R192 WeakPolarHBondContact O-CG 3.11Å; C188-R192 PolarHBondContact O-N 3.28Å; L189-R192 PolarHBondContact O-N 3.14Å; R190-R192 VanDerWaalsContact C-N 3.34Å; R190-R192 PolarHBondContact O-N 2.96Å; R192-M194 VanDerWaalsContact C-N 3.35Å; R192-V195 PolarHBondContact O-N 2.77Å; R192-A196 WeakPolarHBondContact O-CB 3.41Å; R192-A196 PolarHBondContact O-N 3.49Å
193N98.8Very high98.5Very high90 Ų9069.2 Ų69.248%0.48136%0.361SS..Hα-helixtrans-64.4-38.7175-71.1-14.5000112.2L189 R190 L191 A196 S197L189-N193 VanDerWaalsContact O-CG 3.29Å; L189-N193 PolarHBondContact O-N 3.21Å; R190-N193 PolarHBondContact O-N 3.28Å; L191-N193 PolarHBondContact O-N 2.83Å; N193-A196 PolarHBondContact O-N 3.17Å; N193-S197 WeakPolarHBondContact O-CB 3.09Å; N193-S197 PolarHBondContact O-N 2.94Å; N193-S197 PolarHBondContact O-OG 3.48Å
194M98.8Very high98.5Very high37 Ų3767.8 Ų67.818%0.18236%0.355CS..Hα-helixtrans-63-46.3175.2-70.7176.370.200111.3R190 L191 R192 A196 S197 D198 A199 E203 L204 A207R190-M194 HydrophobicContact CG-SD 4.26Å; R190-M194 WeakPolarHBondContact O-CG 3.36Å; R190-M194 PolarHBondContact O-N 3.23Å; L191-M194 HydrophobicContact CD2-SD 4.48Å; L191-M194 WeakPolarHBondContact O-CB 3.36Å; L191-M194 PolarHBondContact O-N 2.94Å; R192-M194 VanDerWaalsContact C-N 3.35Å; M194-A196 VanDerWaalsContact C-N 3.33Å; M194-A196 PolarHBondContact O-N 3.42Å; M194-S197 CarbonylContact O-C 3.49Å; M194-S197 PolarHBondContact O-N 3.1Å; M194-S197 VanDerWaalsContact O-N 3.14Å; M194-D198 PolarHBondContact O-N 2.85Å; M194-A199 HydrophobicContact CB-CB 3.87Å; M194-A199 HydrophobicContact CE-CB 4.29Å; M194-A199 WeakPolarHBondContact O-CB 3.29Å; M194-A199 PolarHBondContact O-N 3.5Å; M194-E203 HydrophobicContact CE-CB 4.31Å; M194-E203 WeakPolarHBondContact CE-O 3.44Å; M194-L204 HydrophobicContact CB-CD2 3.8Å; M194-L204 HydrophobicContact CE-CD2 4.13Å; M194-L204 HydrophobicContact SD-CD2 4.49Å; M194-A207 HydrophobicContact CE-CB 3.7Å; M194-A207 HydrophobicContact SD-CB 3.76Å
195V98.6Very high98.5Very high24 Ų2470.4 Ų70.415%0.14537%0.374CS..Hα-helixtrans-62.1-40.7175.2172.90000111.4V118 A121 Q122 L191 R192 S197 D198 L204V118-V195 HydrophobicContact CG1-CG2 4.13Å; A121-V195 HydrophobicContact CB-CB 3.83Å; A121-V195 HydrophobicContact CB-CG1 3.8Å; A121-V195 HydrophobicContact CB-CG2 3.97Å; Q122-V195 HydrophobicContact CG-CG1 3.92Å; Q122-V195 HydrophobicContact CG-CG2 4.48Å; L191-V195 WeakPolarHBondContact O-CG2 3.44Å; L191-V195 PolarHBondContact O-N 3.29Å; R192-V195 PolarHBondContact O-N 2.77Å; V195-S197 PolarHBondContact O-N 3.31Å; V195-D198 PolarHBondContact O-N 2.95Å; V195-L204 HydrophobicContact CG2-CD1 4.19Å; V195-L204 HydrophobicContact CG2-CD2 4.05Å
196A98.1Very high98.4Very high81 Ų8170.7 Ų70.767%0.66938%0.38SS*.Hα-helixtrans-67.8-20.4176.900000113.8R192 N193 M194R192-A196 WeakPolarHBondContact O-CB 3.41Å; R192-A196 PolarHBondContact O-N 3.49Å; N193-A196 PolarHBondContact O-N 3.17Å; M194-A196 VanDerWaalsContact C-N 3.33Å; M194-A196 PolarHBondContact O-N 3.42Å
197S98.1Very high98.4Very high95 Ų9566.8 Ų66.866%0.66436%0.362SS*.THydrogen-bonded Turntrans-98.718175.9-49.60000112.3N193 M194 V195 A199N193-S197 WeakPolarHBondContact O-CB 3.09Å; N193-S197 PolarHBondContact O-N 2.94Å; N193-S197 PolarHBondContact O-OG 3.48Å; M194-S197 CarbonylContact O-C 3.49Å; M194-S197 PolarHBondContact O-N 3.1Å; M194-S197 VanDerWaalsContact O-N 3.14Å; V195-S197 PolarHBondContact O-N 3.31Å; S197-A199 VanDerWaalsContact C-N 3.26Å; S197-A199 PolarHBondContact O-N 3.01Å
198D97.7Very high98.4Very high146 Ų14666.9 Ų66.978%0.78136%0.363SS*.THydrogen-bonded Turntrans55.234.8179.3-61.4-54.6000114.4M194 V195 T200M194-D198 PolarHBondContact O-N 2.85Å; V195-D198 PolarHBondContact O-N 2.95Å; D198-T200 PolarHBondContact O-N 3.21Å
199A98.1Very high98.4Very high25 Ų2570.6 Ų70.621%0.20738%0.383CS..  trans-56.6140.1174.900000111.5M194 S197 E203 L204M194-A199 HydrophobicContact CB-CB 3.87Å; M194-A199 HydrophobicContact CE-CB 4.29Å; M194-A199 WeakPolarHBondContact O-CB 3.29Å; M194-A199 PolarHBondContact O-N 3.5Å; S197-A199 VanDerWaalsContact C-N 3.26Å; S197-A199 PolarHBondContact O-N 3.01Å; A199-E203 HydrophobicContact CB-CB 4.44Å; A199-L204 HydrophobicContact CB-CD2 4.48Å; A199-L204 HydrophobicContact CB-CG 4.29Å
200T98.2Very high98.4Very high75 Ų7568.5 Ų68.546%0.4638%0.377SS..  trans-68.6160.8179.466.20000111.5D198 V202 E203 L204D198-T200 PolarHBondContact O-N 3.21Å; T200-V202 PolarHBondContact O-N 2.9Å; T200-E203 WeakPolarHBondContact CB-OE2 3.38Å; T200-E203 WeakPolarHBondContact CG2-OE2 3.37Å; T200-E203 PolarHBondContact N-OE2 2.74Å; T200-E203 PolarHBondContact O-N 3.41Å; T200-E203 WeakPolarHBondContact OG1-CG 3.3Å; T200-E203 PolarHBondContact OG1-N 3.08Å; T200-E203 PolarHBondContact OG1-OE2 3.02Å; T200-L204 WeakPolarHBondContact O-CG 3.48Å; T200-L204 PolarHBondContact O-N 3.4Å
201K97.2Very high98.4Very high179 Ų17963 Ų6378%0.77836%0.356SS*.Hα-helixtrans-58.1-32.4174.6-68.5-175.5178.1-178.30112.7S205K201-S205 WeakPolarHBondContact O-CB 3.48Å; K201-S205 PolarHBondContact O-N 3.04Å
202V98.2Very high98.4Very high93 Ų9364.3 Ų64.356%0.56436%0.363SS*.Hα-helixtrans-69.2-50178.6177.50000110.1T200 L204 S205 E206T200-V202 PolarHBondContact O-N 2.9Å; V202-L204 VanDerWaalsContact C-N 3.31Å; V202-L204 PolarHBondContact O-N 3Å; V202-S205 WeakPolarHBondContact O-CB 3.27Å; V202-S205 PolarHBondContact O-N 2.72Å; V202-S205 VanDerWaalsContact O-N 3.08Å; V202-E206 HydrophobicContact CG1-CG 4.5Å; V202-E206 WeakPolarHBondContact O-CG 3.33Å; V202-E206 PolarHBondContact O-N 3.11Å
203E98.5Very high98.4Very high96 Ų9668 Ų6845%0.44938%0.382SS..Hα-helixtrans-60.7-39.6178-69.5163.2134.800112.2M194 A199 T200 A207M194-E203 HydrophobicContact CE-CB 4.31Å; M194-E203 WeakPolarHBondContact CE-O 3.44Å; A199-E203 HydrophobicContact CB-CB 4.44Å; T200-E203 WeakPolarHBondContact CB-OE2 3.38Å; T200-E203 WeakPolarHBondContact CG2-OE2 3.37Å; T200-E203 PolarHBondContact N-OE2 2.74Å; T200-E203 PolarHBondContact O-N 3.41Å; T200-E203 WeakPolarHBondContact OG1-CG 3.3Å; T200-E203 PolarHBondContact OG1-N 3.08Å; T200-E203 PolarHBondContact OG1-OE2 3.02Å; E203-A207 WeakPolarHBondContact O-CB 3.5Å; E203-A207 PolarHBondContact O-N 3.08Å
204L98.5Very high98.4Very high10 Ų1067.9 Ų67.95%0.05238%0.378CS..Hα-helixtrans-63.5-42.8174.1-72.6168.1000111.7V118 L191 M194 V195 A199 T200 V202 A207 I208V118-L204 HydrophobicContact CG1-CD1 4.12Å; V118-L204 HydrophobicContact CG2-CD2 4.3Å; L191-L204 HydrophobicContact CD2-CD2 4.29Å; M194-L204 HydrophobicContact CB-CD2 3.8Å; M194-L204 HydrophobicContact CE-CD2 4.13Å; M194-L204 HydrophobicContact SD-CD2 4.49Å; V195-L204 HydrophobicContact CG2-CD1 4.19Å; V195-L204 HydrophobicContact CG2-CD2 4.05Å; A199-L204 HydrophobicContact CB-CD2 4.48Å; A199-L204 HydrophobicContact CB-CG 4.29Å; T200-L204 WeakPolarHBondContact O-CG 3.48Å; T200-L204 PolarHBondContact O-N 3.4Å; V202-L204 VanDerWaalsContact C-N 3.31Å; V202-L204 PolarHBondContact O-N 3Å; L204-A207 PolarHBondContact O-N 3.26Å; L204-I208 VanDerWaalsContact O-CG1 3.26Å; L204-I208 WeakPolarHBondContact O-CG1 3.3Å; L204-I208 PolarHBondContact O-N 3.13Å
205S98.3Very high98.4Very high55 Ų5566.2 Ų66.239%0.38537%0.37SS..Hα-helixtrans-61.8-49.1177.3-165.50000111.5K201 V202 A207 I208 D209K201-S205 WeakPolarHBondContact O-CB 3.48Å; K201-S205 PolarHBondContact O-N 3.04Å; V202-S205 WeakPolarHBondContact O-CB 3.27Å; V202-S205 PolarHBondContact O-N 2.72Å; V202-S205 VanDerWaalsContact O-N 3.08Å; S205-A207 VanDerWaalsContact C-N 3.29Å; S205-A207 PolarHBondContact O-N 3.17Å; S205-I208 PolarHBondContact O-N 2.94Å; S205-I208 VanDerWaalsContact O-N 3.13Å; S205-D209 VanDerWaalsContact O-CG 3.3Å; S205-D209 PolarHBondContact O-N 3.12Å
206E98.5Very high98.4Very high117 Ų11769 Ų6955%0.54738%0.381SS..Hα-helixtrans-61.6-37.4179.4-70175.617100112.2V202 D209 S210V202-E206 HydrophobicContact CG1-CG 4.5Å; V202-E206 WeakPolarHBondContact O-CG 3.33Å; V202-E206 PolarHBondContact O-N 3.11Å; E206-D209 PolarHBondContact O-N 2.78Å; E206-S210 PolarHBondContact O-N 3.36Å; E206-S210 VanDerWaalsContact O-N 3.08Å; E206-S210 PolarHBondContact O-OG 3Å
207A98.8Very high98.4Very high5 Ų572.4 Ų72.44%0.04138%0.376CS..Hα-helixtrans-66.3-43.7174.200000112M194 E203 L204 S205 D209 S210 M211M194-A207 HydrophobicContact CE-CB 3.7Å; M194-A207 HydrophobicContact SD-CB 3.76Å; E203-A207 WeakPolarHBondContact O-CB 3.5Å; E203-A207 PolarHBondContact O-N 3.08Å; L204-A207 PolarHBondContact O-N 3.26Å; S205-A207 VanDerWaalsContact C-N 3.29Å; S205-A207 PolarHBondContact O-N 3.17Å; A207-D209 VanDerWaalsContact C-N 3.34Å; A207-S210 PolarHBondContact O-N 3.06Å; A207-M211 HydrophobicContact CB-CE 4.4Å; A207-M211 WeakPolarHBondContact O-CG 3.29Å; A207-M211 PolarHBondContact O-N 2.93Å
208I98.8Very high98.5Very high5 Ų569.3 Ų69.33%0.02635%0.353CS..Hα-helixtrans-63-41.4176.1-69.1170.8000110.6Y111 L114 V118 L191 L204 S205 S210 M211 I212Y111-I208 HydrophobicContact CD2-CG2 3.69Å; Y111-I208 HydrophobicContact CE2-CG2 3.4Å; Y111-I208 VanDerWaalsContact CE2-CG2 3.4Å; L114-I208 HydrophobicContact CB-CG1 4.31Å; L114-I208 HydrophobicContact CB-CG2 4.24Å; L114-I208 HydrophobicContact CD1-CG2 4.02Å; V118-I208 HydrophobicContact CG2-CD1 4.15Å; L191-I208 HydrophobicContact CD1-CG1 4.34Å; L191-I208 HydrophobicContact CD2-CG1 3.89Å; L204-I208 VanDerWaalsContact O-CG1 3.26Å; L204-I208 WeakPolarHBondContact O-CG1 3.3Å; L204-I208 PolarHBondContact O-N 3.13Å; S205-I208 PolarHBondContact O-N 2.94Å; S205-I208 VanDerWaalsContact O-N 3.13Å; I208-S210 VanDerWaalsContact C-N 3.33Å; I208-S210 PolarHBondContact O-N 3.05Å; I208-M211 WeakPolarHBondContact O-CB 3.16Å; I208-M211 PolarHBondContact O-N 3Å; I208-M211 VanDerWaalsContact O-N 3.17Å; I208-I212 PolarHBondContact O-N 2.9Å
209D98.7Very high98.5Very high82 Ų8262.4 Ų62.444%0.43932%0.316SS..Hα-helixtrans-61.1-42.4177.9-70.4-22.7000111.4S205 E206 A207 I212 E213S205-D209 VanDerWaalsContact O-CG 3.3Å; S205-D209 PolarHBondContact O-N 3.12Å; E206-D209 PolarHBondContact O-N 2.78Å; A207-D209 VanDerWaalsContact C-N 3.34Å; D209-I212 WeakPolarHBondContact O-CG2 3.3Å; D209-I212 PolarHBondContact O-N 3.28Å; D209-E213 PolarHBondContact O-N 3.43Å; D209-E213 VanDerWaalsContact O-N 3.09Å
210S98.7Very high98.5Very high62 Ų6262.2 Ų62.243%0.43431%0.314SS..Hα-helixtrans-64.8-40.7174.5-56.20000112.1E206 A207 I208 E213 E214E206-S210 PolarHBondContact O-N 3.36Å; E206-S210 VanDerWaalsContact O-N 3.08Å; E206-S210 PolarHBondContact O-OG 3Å; A207-S210 PolarHBondContact O-N 3.06Å; I208-S210 VanDerWaalsContact C-N 3.33Å; I208-S210 PolarHBondContact O-N 3.05Å; S210-E213 PolarHBondContact O-N 2.72Å; S210-E214 PolarHBondContact O-N 2.88Å
211M98.8Very high98.6Very high2 Ų264.4 Ų64.41%0.0133%0.327CS..Hα-helixtrans-66.3-41.5179-71.7166.9-175.800112.1L114 Y187 R190 L191 A207 I208 E213 E214 V215L114-M211 HydrophobicContact CD1-CB 3.78Å; L114-M211 HydrophobicContact CD1-SD 4.44Å; L114-M211 HydrophobicContact CD2-SD 4.14Å; Y187-M211 HydrophobicContact CD1-CB 4.43Å; Y187-M211 HydrophobicContact CD1-CE 4.11Å; Y187-M211 HydrophobicContact CD1-CG 3.67Å; Y187-M211 HydrophobicContact CD1-SD 4.07Å; Y187-M211 HydrophobicContact CD2-CB 3.7Å; Y187-M211 HydrophobicContact CD2-CG 3.79Å; Y187-M211 HydrophobicContact CD2-SD 4.19Å; Y187-M211 HydrophobicContact CE1-CB 4.37Å; Y187-M211 HydrophobicContact CE1-CG 3.82Å; Y187-M211 HydrophobicContact CE2-CB 3.62Å; Y187-M211 HydrophobicContact CE2-CG 3.93Å; Y187-M211 HydrophobicContact CG-CB 4.11Å; Y187-M211 HydrophobicContact CG-CE 4.26Å; Y187-M211 HydrophobicContact CG-CG 3.65Å; Y187-M211 HydrophobicContact CG-SD 3.72Å; R190-M211 HydrophobicContact CB-CE 4.05Å; R190-M211 HydrophobicContact CG-CE 3.87Å; L191-M211 HydrophobicContact CD1-SD 4.01Å; L191-M211 HydrophobicContact CD2-CE 4.01Å; L191-M211 HydrophobicContact CD2-SD 4.04Å; L191-M211 HydrophobicContact CG-CE 3.95Å; L191-M211 HydrophobicContact CG-SD 3.95Å; A207-M211 HydrophobicContact CB-CE 4.4Å; A207-M211 WeakPolarHBondContact O-CG 3.29Å; A207-M211 PolarHBondContact O-N 2.93Å; I208-M211 WeakPolarHBondContact O-CB 3.16Å; I208-M211 PolarHBondContact O-N 3Å; I208-M211 VanDerWaalsContact O-N 3.17Å; M211-E213 VanDerWaalsContact C-N 3.33Å; M211-E214 PolarHBondContact O-N 3.04Å; M211-V215 WeakPolarHBondContact O-CG2 3.48Å; M211-V215 PolarHBondContact O-N 3.48Å; M211-V215 VanDerWaalsContact O-N 3.17Å
212I98.7Very high98.6Very high28 Ų2857.2 Ų57.214%0.14430%0.298CS..Hα-helixtrans-72.7-28.1179.9-157.566.5000111.7I107 C110 Y111 I208 D209 E214 V215 F216I107-I212 HydrophobicContact CG2-CD1 4.28Å; I107-I212 HydrophobicContact CG2-CG1 4.26Å; C110-I212 HydrophobicContact CB-CD1 4Å; Y111-I212 HydrophobicContact CD2-CB 4.42Å; Y111-I212 HydrophobicContact CD2-CD1 4.43Å; Y111-I212 HydrophobicContact CD2-CG1 4.26Å; I208-I212 PolarHBondContact O-N 2.9Å; D209-I212 WeakPolarHBondContact O-CG2 3.3Å; D209-I212 PolarHBondContact O-N 3.28Å; I212-E214 VanDerWaalsContact C-N 3.35Å; I212-V215 HydrophobicContact CD1-CB 4.04Å; I212-V215 HydrophobicContact CD1-CG1 4.15Å; I212-V215 HydrophobicContact CD1-CG2 4.34Å; I212-V215 WeakPolarHBondContact O-CB 3.31Å; I212-V215 PolarHBondContact O-N 3.45Å; I212-F216 WeakPolarHBondContact O-CB 3.47Å; I212-F216 PolarHBondContact O-N 3.03Å
213E98.8Very high98.7Very high120 Ų12053.2 Ų53.256%0.56127%0.274SS*.Hα-helixtrans-60.2-43.6170-167.4-166.3141.600111.6D209 S210 M211 F216 R217D209-E213 PolarHBondContact O-N 3.43Å; D209-E213 VanDerWaalsContact O-N 3.09Å; S210-E213 PolarHBondContact O-N 2.72Å; M211-E213 VanDerWaalsContact C-N 3.33Å; E213-F216 WeakPolarHBondContact O-CB 3.43Å; E213-F216 PolarHBondContact O-N 2.82Å; E213-R217 PolarHBondContact O-N 3.23Å; E213-R217 IonicContact OE1-NH2 3.81Å
214E98.8Very high98.7Very high88 Ų8850 Ų5041%0.41127%0.267SS..Hα-helixtrans-64.4-39.6174.9-72.6-169.7-150.600112.2K183 Y187 S210 M211 I212 F216 R217 V218K183-E214 WeakPolarHBondContact CE-OE2 3.49Å; K183-E214 IonicContact NZ-OE2 2.85Å; K183-E214 PolarHBondContact NZ-OE2 2.92Å; Y187-E214 WeakPolarHBondContact OH-CB 3.37Å; Y187-E214 PolarHBondContact OH-OE2 3.22Å; S210-E214 PolarHBondContact O-N 2.88Å; M211-E214 PolarHBondContact O-N 3.04Å; I212-E214 VanDerWaalsContact C-N 3.35Å; E214-F216 VanDerWaalsContact C-N 3.35Å; E214-R217 WeakPolarHBondContact O-CB 3.41Å; E214-R217 PolarHBondContact O-N 3.39Å; E214-V218 WeakPolarHBondContact O-CG2 3.25Å; E214-V218 PolarHBondContact O-N 3.45Å; E214-V218 VanDerWaalsContact O-N 3.08Å
215V98.7Very high98.6Very high2 Ų253.6 Ų53.61%0.01229%0.293CS..Hα-helixtrans-61.4-45.7173.6171.60000110.4I107 C110 L180 L184 Y187 M211 I212 R217 V218 A219I107-V215 HydrophobicContact CD1-CG1 3.82Å; C110-V215 HydrophobicContact CB-CB 4.47Å; C110-V215 HydrophobicContact CB-CG1 3.71Å; C110-V215 HydrophobicContact CB-CG2 4.1Å; L180-V215 HydrophobicContact CD2-CB 4.43Å; L180-V215 HydrophobicContact CD2-CG1 4.06Å; L180-V215 HydrophobicContact CD2-CG2 4.4Å; L184-V215 HydrophobicContact CD2-CG2 4.41Å; Y187-V215 HydrophobicContact CE2-CG2 4.34Å; M211-V215 WeakPolarHBondContact O-CG2 3.48Å; M211-V215 PolarHBondContact O-N 3.48Å; M211-V215 VanDerWaalsContact O-N 3.17Å; I212-V215 HydrophobicContact CD1-CB 4.04Å; I212-V215 HydrophobicContact CD1-CG1 4.15Å; I212-V215 HydrophobicContact CD1-CG2 4.34Å; I212-V215 WeakPolarHBondContact O-CB 3.31Å; I212-V215 PolarHBondContact O-N 3.45Å; V215-R217 VanDerWaalsContact C-N 3.31Å; V215-R217 PolarHBondContact O-N 2.87Å; V215-V218 PolarHBondContact O-N 2.99Å; V215-A219 WeakPolarHBondContact O-CB 3.38Å; V215-A219 PolarHBondContact O-N 3.24Å
216F98.6Very high98.5Very high82 Ų8251.9 Ų51.936%0.3628%0.281SS..Hα-helixtrans-59.3-44.1177.8-159.9-83.5000111F103 W104 I107 I212 E213 E214 V218 A219 S220F103-F216 AromaticContact CE1-CE2 3.93Å; F103-F216 HydrophobicContact CE1-CE2 3.93Å; F103-F216 HydrophobicContact CE1-CZ 4.17Å; F103-F216 HydrophobicContact CZ-CD2 4.32Å; F103-F216 HydrophobicContact CZ-CE1 4.27Å; F103-F216 AromaticContact CZ-CE2 3.78Å; F103-F216 HydrophobicContact CZ-CE2 3.78Å; F103-F216 AromaticContact CZ-CZ 3.76Å; F103-F216 HydrophobicContact CZ-CZ 3.76Å; W104-F216 HydrophobicContact CZ3-CE2 4.36Å; I107-F216 HydrophobicContact CD1-CB 4.28Å; I107-F216 HydrophobicContact CD1-CD2 3.99Å; I107-F216 HydrophobicContact CD1-CG 4.41Å; I107-F216 HydrophobicContact CG1-CD2 4.11Å; I107-F216 HydrophobicContact CG2-CD2 4.34Å; I212-F216 WeakPolarHBondContact O-CB 3.47Å; I212-F216 PolarHBondContact O-N 3.03Å; E213-F216 WeakPolarHBondContact O-CB 3.43Å; E213-F216 PolarHBondContact O-N 2.82Å; E214-F216 VanDerWaalsContact C-N 3.35Å; F216-V218 PolarHBondContact O-N 3.36Å; F216-A219 PolarHBondContact O-N 3.03Å; F216-S220 WeakPolarHBondContact CD1-OG 3.39Å; F216-S220 VanDerWaalsContact CE1-OG 3.29Å; F216-S220 WeakPolarHBondContact CE1-OG 3.27Å; F216-S220 WeakPolarHBondContact O-CB 3.36Å; F216-S220 PolarHBondContact O-N 2.89Å; F216-S220 PolarHBondContact O-OG 3.41Å; F216-S220 VanDerWaalsContact O-OG 3.13Å
217R98.8Very high98.5Very high153 Ų15348 Ų4858%0.57727%0.265SS*.Hα-helixtrans-55.7-49.5174.2-178-175.7-59.8-79.8-5.3112E213 E214 V215 V221E213-R217 PolarHBondContact O-N 3.23Å; E213-R217 IonicContact OE1-NH2 3.81Å; E214-R217 WeakPolarHBondContact O-CB 3.41Å; E214-R217 PolarHBondContact O-N 3.39Å; V215-R217 VanDerWaalsContact C-N 3.31Å; V215-R217 PolarHBondContact O-N 2.87Å; R217-V221 WeakPolarHBondContact O-CB 3.34Å; R217-V221 WeakPolarHBondContact O-CG2 3.39Å; R217-V221 PolarHBondContact O-N 3.4Å
218V98.8Very high98.4Very high31 Ų3154.7 Ų54.719%0.18830%0.3CS..Hα-helixtrans-63.7-48.2179.6174.10000110.9M176 I179 L180 E214 V215 F216 S220 V221 C222M176-V218 HydrophobicContact CG-CG1 4.39Å; I179-V218 HydrophobicContact CG2-CG1 4.1Å; I179-V218 HydrophobicContact CG2-CG2 4.22Å; L180-V218 HydrophobicContact CD2-CB 3.81Å; L180-V218 HydrophobicContact CD2-CG1 3.7Å; L180-V218 HydrophobicContact CD2-CG2 4.41Å; L180-V218 HydrophobicContact CG-CG1 3.98Å; E214-V218 WeakPolarHBondContact O-CG2 3.25Å; E214-V218 PolarHBondContact O-N 3.45Å; E214-V218 VanDerWaalsContact O-N 3.08Å; V215-V218 PolarHBondContact O-N 2.99Å; F216-V218 PolarHBondContact O-N 3.36Å; V218-S220 PolarHBondContact O-N 3.22Å; V218-V221 PolarHBondContact O-N 3.04Å; V218-C222 WeakPolarHBondContact O-CB 3.41Å; V218-C222 PolarHBondContact O-N 2.83Å; V218-C222 PolarHBondContact O-SG 3.31Å
219A98.5Very high98.4Very high0 Ų058.4 Ų58.40%032%0.323CS..Hα-helixtrans-61.4-45.818000000112F103 I107 V215 F216 V221 C222 L223F103-A219 HydrophobicContact CD2-CB 4.35Å; F103-A219 HydrophobicContact CE2-CB 4Å; I107-A219 HydrophobicContact CD1-CB 3.58Å; V215-A219 WeakPolarHBondContact O-CB 3.38Å; V215-A219 PolarHBondContact O-N 3.24Å; F216-A219 PolarHBondContact O-N 3.03Å; A219-V221 PolarHBondContact O-N 2.87Å; A219-C222 PolarHBondContact O-N 3.37Å; A219-L223 VanDerWaalsContact O-CB 3.28Å; A219-L223 WeakPolarHBondContact O-CB 3.37Å; A219-L223 WeakPolarHBondContact O-CG 3.36Å; A219-L223 PolarHBondContact O-N 2.98Å
220S98.6Very high98.4Very high22 Ų2254.8 Ų54.815%0.15430%0.304CS..Hα-helixtrans-64.8-37.3178.1-660000112.9F216 V218 C222 G224F216-S220 WeakPolarHBondContact CD1-OG 3.39Å; F216-S220 VanDerWaalsContact CE1-OG 3.29Å; F216-S220 WeakPolarHBondContact CE1-OG 3.27Å; F216-S220 WeakPolarHBondContact O-CB 3.36Å; F216-S220 PolarHBondContact O-N 2.89Å; F216-S220 PolarHBondContact O-OG 3.41Å; F216-S220 VanDerWaalsContact O-OG 3.13Å; V218-S220 PolarHBondContact O-N 3.22Å; S220-C222 VanDerWaalsContact C-N 3.33Å; S220-G224 CarbonylContact O-C 3.38Å; S220-G224 WeakPolarHBondContact O-CA 3.39Å; S220-G224 PolarHBondContact O-N 2.9Å
221V98.8Very high98.3Very high120 Ų12055 Ų5573%0.72731%0.305SS*.Hα-helixtrans-65.1-38.7173.6168.20000111.2R217 V218 A219R217-V221 WeakPolarHBondContact O-CB 3.34Å; R217-V221 WeakPolarHBondContact O-CG2 3.39Å; R217-V221 PolarHBondContact O-N 3.4Å; V218-V221 PolarHBondContact O-N 3.04Å; A219-V221 PolarHBondContact O-N 2.87Å
222C98.8Very high98.3Very high28 Ų2855.5 Ų55.519%0.18931%0.307CS..Hα-helixtrans-82-33.2-175.7-77.60000114.4S167 S169 M176 V218 A219 S220S167-C222 PolarHBondContact OG-O 3.23Å; S169-C222 WeakPolarHBondContact CB-O 3.46Å; S169-C222 WeakPolarHBondContact OG-CB 3.4Å; S169-C222 PolarHBondContact OG-O 3.45Å; S169-C222 VanDerWaalsContact OG-O 3.12Å; M176-C222 HydrophobicContact CB-CB 4.34Å; M176-C222 HydrophobicContact CG-CB 3.89Å; M176-C222 HydrophobicContact SD-CB 3.54Å; M176-C222 VanDerWaalsContact SD-CB 3.54Å; V218-C222 WeakPolarHBondContact O-CB 3.41Å; V218-C222 PolarHBondContact O-N 2.83Å; V218-C222 PolarHBondContact O-SG 3.31Å; A219-C222 PolarHBondContact O-N 3.37Å; S220-C222 VanDerWaalsContact C-N 3.33Å
223L98.7Very high98.3Very high9 Ų958.4 Ų58.45%0.04732%0.32CS..Hα-helixtrans-119.3-13.7-168.2-56.5176.9000113.5F102 F103 F164 M176 A219F102-L223 HydrophobicContact CD1-CD1 4.06Å; F102-L223 HydrophobicContact CD1-CD2 4.11Å; F102-L223 HydrophobicContact CE1-CD1 4.31Å; F102-L223 HydrophobicContact CE1-CD2 4.11Å; F103-L223 HydrophobicContact CB-CD1 4.12Å; F103-L223 HydrophobicContact CD2-CB 4.07Å; F103-L223 HydrophobicContact CD2-CD1 4.02Å; F164-L223 VanDerWaalsContact CZ-O 3.27Å; F164-L223 WeakPolarHBondContact CZ-O 3.23Å; M176-L223 HydrophobicContact CE-CD1 4.33Å; M176-L223 HydrophobicContact CE-CD2 4.46Å; M176-L223 HydrophobicContact SD-CD1 4.01Å; M176-L223 HydrophobicContact SD-CD2 4.09Å; M176-L223 HydrophobicContact SD-CG 3.9Å; A219-L223 VanDerWaalsContact O-CB 3.28Å; A219-L223 WeakPolarHBondContact O-CB 3.37Å; A219-L223 WeakPolarHBondContact O-CG 3.36Å; A219-L223 PolarHBondContact O-N 2.98Å
224G98.3Very high98.2Very high30 Ų3054 Ų5431%0.30930%0.298SS..  trans86.5176.9-167.700000112.7F103 S220F103-G224 WeakPolarHBondContact CE2-O 3.14Å; S220-G224 CarbonylContact O-C 3.38Å; S220-G224 WeakPolarHBondContact O-CA 3.39Å; S220-G224 PolarHBondContact O-N 2.9Å
225S97.1Very high98.2Very high85 Ų8557.6 Ų57.659%0.59431%0.308SS*.PPolyproline II helixtrans-99.7125.2178.8-59.10000110.3F164F164-S225 WeakPolarHBondContact CE2-O 3.47Å
226P97.1Very high98.1Very high19 Ų1958.4 Ų58.412%0.12331%0.312CS..PPolyproline II helixtrans-58.1142174.8-22.631.6000111.7Y100 F103 W104 F164Y100-P226 HydrophobicContact CD2-CB 3.97Å; Y100-P226 HydrophobicContact CE2-CB 3.76Å; F103-P226 HydrophobicContact CB-CG 4.34Å; F103-P226 HydrophobicContact CD1-CG 3.23Å; F103-P226 HydrophobicContact CD2-CG 4.09Å; F103-P226 HydrophobicContact CE1-CG 3.41Å; F103-P226 VanDerWaalsContact CE1-CG 3.41Å; F103-P226 HydrophobicContact CE2-CG 4.23Å; F103-P226 HydrophobicContact CG-CG 3.62Å; F103-P226 HydrophobicContact CZ-CG 3.92Å; W104-P226 HydrophobicContact CZ2-CB 4.15Å; W104-P226 HydrophobicContact CZ2-CG 4.1Å; F164-P226 HydrophobicContact CZ-CG 4.48Å
227P97.4Very high98.1Very high35 Ų3559.6 Ų59.623%0.22732%0.317CS..PPolyproline II helixtrans-75.4139.4-179.130.2-34.6000111.9I159 T229 I230I159-P227 HydrophobicContact CD1-CG 3.99Å; P227-T229 VanDerWaalsContact C-N 3.33Å; P227-I230 HydrophobicContact CB-CG2 4.23Å; P227-I230 HydrophobicContact CG-CG2 3.68Å
228D97.1Very high98Very high145 Ų14557.4 Ų57.478%0.77532%0.317SS*.SBendtrans-66.8-38.2171.5-64.2-36.5000111.7T248 P249D228-T248 WeakPolarHBondContact O-CA 3.05Å; D228-P249 WeakPolarHBondContact O-CD 3.48Å
229T98.4Very high98Very high83 Ų8363.6 Ų63.651%0.50934%0.341SS..SBendtrans-137.7149.3176.561.70000111.1P227 L247 T248P227-T229 VanDerWaalsContact C-N 3.33Å; T229-L247 CarbonylContact C-O 3.54Å; T229-L247 VanDerWaalsContact CA-O 3.25Å; T229-L247 WeakPolarHBondContact CA-O 2.98Å; T229-T248 HydrophobicContact CG2-CG2 4.23Å
230I98.1Very high98Very high7 Ų767.8 Ų67.84%0.03636%0.364CS..EExtended strand (participates in β ladder)trans-118.2147176.760.9163.7000110.6I159 P160 C163 P227 P246 L247 F252I159-I230 HydrophobicContact CB-CD1 4.17Å; I159-I230 HydrophobicContact CB-CG2 4.47Å; I159-I230 HydrophobicContact CG2-CD1 3.91Å; I159-I230 HydrophobicContact CG2-CG2 4.06Å; P160-I230 HydrophobicContact CG-CD1 4.47Å; C163-I230 HydrophobicContact CB-CB 4.28Å; C163-I230 HydrophobicContact CB-CG2 3.78Å; P227-I230 HydrophobicContact CB-CG2 4.23Å; P227-I230 HydrophobicContact CG-CG2 3.68Å; I230-P246 WeakPolarHBondContact O-CA 3.36Å; I230-L247 WeakPolarHBondContact CG1-O 3.21Å; I230-L247 PolarHBondContact N-O 2.93Å; I230-L247 PolarHBondContact O-N 3.46Å; I230-F252 HydrophobicContact CD1-CB 4.18Å; I230-F252 HydrophobicContact CD1-CD2 3.81Å; I230-F252 HydrophobicContact CD1-CE2 4.4Å; I230-F252 HydrophobicContact CD1-CG 4Å
231C97.8Very high97.9Very high67 Ų6771.8 Ų71.845%0.45338%0.378SS..EExtended strand (participates in β ladder)trans-128100.7164.6-1670000107.4R243C231-R243 VanDerWaalsContact SG-CD 3.54Å; C231-R243 VanDerWaalsContact SG-CG 3.56Å
232W98.2Very high97.9Very high12 Ų1269.1 Ų69.15%0.04536%0.358CS..EExtended strand (participates in β ladder)trans-98121.9-174.9178.948.6000110.6F85 L91 F94 P160 Y234 R243 M244 F252F85-W232 HydrophobicContact CE1-CH2 4.12Å; F85-W232 AromaticContact CE1-CZ3 3.95Å; F85-W232 HydrophobicContact CE1-CZ3 3.95Å; F85-W232 AromaticContact CZ-CZ3 3.92Å; F85-W232 HydrophobicContact CZ-CZ3 3.92Å; L91-W232 HydrophobicContact CD1-CH2 3.69Å; L91-W232 HydrophobicContact CD2-CH2 4.06Å; F94-W232 AromaticContact CD2-CH2 3.62Å; F94-W232 HydrophobicContact CD2-CH2 3.62Å; F94-W232 AromaticContact CD2-CZ2 3.6Å; F94-W232 HydrophobicContact CD2-CZ2 3.6Å; F94-W232 AromaticContact CE2-CH2 3.51Å; F94-W232 HydrophobicContact CE2-CH2 3.51Å; F94-W232 AromaticContact CE2-CZ2 3.58Å; F94-W232 HydrophobicContact CE2-CZ2 3.58Å; F94-W232 HydrophobicContact CE2-CZ3 4.03Å; P160-W232 HydrophobicContact CB-CD2 3.97Å; P160-W232 HydrophobicContact CB-CG 3.92Å; P160-W232 HydrophobicContact CG-CB 3.98Å; P160-W232 HydrophobicContact CG-CD2 3.53Å; P160-W232 HydrophobicContact CG-CE3 3.83Å; P160-W232 HydrophobicContact CG-CG 3.58Å; W232-Y234 AromaticContact CD2-CD1 3.81Å; W232-Y234 HydrophobicContact CD2-CD1 3.81Å; W232-Y234 HydrophobicContact CD2-CE1 4.47Å; W232-Y234 AromaticContact CE2-CD1 3.84Å; W232-Y234 AromaticContact CE3-CD1 3.58Å; W232-Y234 HydrophobicContact CE3-CD1 3.58Å; W232-Y234 AromaticContact CE3-CE1 3.79Å; W232-Y234 HydrophobicContact CE3-CE1 3.79Å; W232-Y234 AromaticContact CH2-CD1 3.42Å; W232-Y234 HydrophobicContact CH2-CD1 3.42Å; W232-Y234 VanDerWaalsContact CH2-CD1 3.42Å; W232-Y234 HydrophobicContact CH2-CD2 4.3Å; W232-Y234 AromaticContact CH2-CE1 3.77Å; W232-Y234 HydrophobicContact CH2-CE1 3.77Å; W232-Y234 AromaticContact CH2-CG 3.7Å; W232-Y234 HydrophobicContact CH2-CG 3.7Å; W232-Y234 AromaticContact CZ2-CD1 3.67Å; W232-Y234 HydrophobicContact CZ2-CD1 3.67Å; W232-Y234 HydrophobicContact CZ2-CE1 4.47Å; W232-Y234 AromaticContact CZ2-CG 3.73Å; W232-Y234 HydrophobicContact CZ2-CG 3.73Å; W232-Y234 AromaticContact CZ3-CD1 3.38Å; W232-Y234 HydrophobicContact CZ3-CD1 3.38Å; W232-Y234 AromaticContact CZ3-CE1 3.4Å; W232-Y234 HydrophobicContact CZ3-CE1 3.4Å; W232-Y234 HydrophobicContact CZ3-CG 4.15Å; W232-R243 CarbonylContact O-C 3.48Å; W232-R243 WeakPolarHBondContact O-CA 3.42Å; W232-M244 HydrophobicContact CE3-CB 4.48Å; W232-M244 HydrophobicContact CE3-SD 4.5Å; W232-M244 PolarHBondContact N-O 2.92Å; W232-M244 PolarHBondContact O-N 3.13Å; W232-F252 HydrophobicContact CE3-CE2 4.34Å
233E98.3Very high97.9Very high89 Ų8975.2 Ų75.242%0.41638%0.377SS..EExtended strand (participates in β ladder)trans-107.5137.8175.9-62.3-176.7163.500110.3F241 H242 R243E233-F241 HydrophobicContact CB-CE2 3.91Å; E233-F241 HydrophobicContact CB-CZ 4.26Å; E233-F241 HydrophobicContact CG-CE2 4.05Å; E233-F241 HydrophobicContact CG-CZ 3.91Å; E233-H242 WeakPolarHBondContact CA-O 3.34Å; E233-R243 HydrophobicContact CG-CB 4.34Å; E233-R243 HydrophobicContact CG-CG 4.1Å; E233-R243 IonicContact OE1-CZ 3.61Å; E233-R243 IonicContact OE1-NE 2.87Å; E233-R243 PolarHBondContact OE1-NE 3.28Å; E233-R243 IonicContact OE1-NH2 2.77Å; E233-R243 PolarHBondContact OE1-NH2 3.01Å
234Y97.9Very high97.7Very high26 Ų2675.5 Ų75.510%0.10238%0.379CS..EExtended strand (participates in β ladder)trans-151.2164.517867.1-86.8000111.3H89 L91 W232 H242H89-Y234 PolarHBondContact ND1-OH 2.89Å; L91-Y234 HydrophobicContact CD2-CD2 3.27Å; L91-Y234 HydrophobicContact CD2-CE2 3.38Å; L91-Y234 HydrophobicContact CD2-CG 4.07Å; W232-Y234 AromaticContact CD2-CD1 3.81Å; W232-Y234 HydrophobicContact CD2-CD1 3.81Å; W232-Y234 HydrophobicContact CD2-CE1 4.47Å; W232-Y234 AromaticContact CE2-CD1 3.84Å; W232-Y234 AromaticContact CE3-CD1 3.58Å; W232-Y234 HydrophobicContact CE3-CD1 3.58Å; W232-Y234 AromaticContact CE3-CE1 3.79Å; W232-Y234 HydrophobicContact CE3-CE1 3.79Å; W232-Y234 AromaticContact CH2-CD1 3.42Å; W232-Y234 HydrophobicContact CH2-CD1 3.42Å; W232-Y234 VanDerWaalsContact CH2-CD1 3.42Å; W232-Y234 HydrophobicContact CH2-CD2 4.3Å; W232-Y234 AromaticContact CH2-CE1 3.77Å; W232-Y234 HydrophobicContact CH2-CE1 3.77Å; W232-Y234 AromaticContact CH2-CG 3.7Å; W232-Y234 HydrophobicContact CH2-CG 3.7Å; W232-Y234 AromaticContact CZ2-CD1 3.67Å; W232-Y234 HydrophobicContact CZ2-CD1 3.67Å; W232-Y234 HydrophobicContact CZ2-CE1 4.47Å; W232-Y234 AromaticContact CZ2-CG 3.73Å; W232-Y234 HydrophobicContact CZ2-CG 3.73Å; W232-Y234 AromaticContact CZ3-CD1 3.38Å; W232-Y234 HydrophobicContact CZ3-CD1 3.38Å; W232-Y234 AromaticContact CZ3-CE1 3.4Å; W232-Y234 HydrophobicContact CZ3-CE1 3.4Å; W232-Y234 HydrophobicContact CZ3-CG 4.15Å; Y234-H242 HydrophobicContact CD1-CB 3.98Å; Y234-H242 HydrophobicContact CD2-CB 4.1Å; Y234-H242 HydrophobicContact CE1-CB 3.55Å; Y234-H242 HydrophobicContact CE2-CB 3.66Å; Y234-H242 AromaticContact CE2-CD2 3.66Å; Y234-H242 AromaticContact CE2-CG 3.77Å; Y234-H242 HydrophobicContact CG-CB 4.25Å; Y234-H242 AromaticContact CZ-CG 3.76Å; Y234-H242 PolarHBondContact N-O 3.47Å; Y234-H242 PolarHBondContact O-N 3.32Å
235R98.1Very high97.6Very high165 Ų16575.5 Ų75.562%0.62338%0.378SS*.EExtended strand (participates in β ladder)trans-109.9136.6163.7-69.6-174.4-179.1-87.5-2.2109K239 N240R235-K239 PolarHBondContact NH1-O 3.33Å; R235-N240 WeakPolarHBondContact CA-O 3.44Å
236D97.6Very high97.6Very high19 Ų1976.4 Ų76.410%0.10238%0.382CS..  trans-77179.5172.664.614.6000111.1N90 D238 K239 N240 H242N90-D236 HydrophobicContact CB-CB 4.22Å; N90-D236 WeakPolarHBondContact O-CA 3.39Å; N90-D236 WeakPolarHBondContact O-CB 3.42Å; D236-D238 PolarHBondContact O-N 3.43Å; D236-D238 VanDerWaalsContact OD1-C 3.29Å; D236-D238 WeakPolarHBondContact OD1-CA 3.47Å; D236-D238 WeakPolarHBondContact OD1-CB 3.32Å; D236-D238 PolarHBondContact OD1-N 3.5Å; D236-K239 WeakPolarHBondContact O-CA 3.44Å; D236-K239 PolarHBondContact O-N 3.26Å; D236-K239 PolarHBondContact OD1-N 3.1Å; D236-N240 PolarHBondContact N-O 2.94Å; D236-N240 PolarHBondContact OD1-N 3.03Å; D236-H242 IonicContact OD2-CD2 3.73Å; D236-H242 IonicContact OD2-CE1 3.37Å; D236-H242 IonicContact OD2-NE2 2.83Å; D236-H242 PolarHBondContact OD2-NE2 3.46Å
237K96.9Very high97.6Very high106 Ų10676.4 Ų76.446%0.46138%0.381SS..THydrogen-bonded Turntrans-59.6-24.6176.2-70.7179.3-167170.40113.6N90 L91 E92 K239N90-K237 WeakPolarHBondContact O-CG 3.15Å; N90-K237 PolarHBondContact O-N 2.65Å; N90-K237 WeakPolarHBondContact OD1-CD 3.05Å; L91-K237 VanDerWaalsContact C-CE 3.43Å; L91-K237 WeakPolarHBondContact O-CE 3.16Å; E92-K237 HydrophobicContact CB-CG 4.08Å; K237-K239 PolarHBondContact O-N 2.94Å
238D98.1Very high97.7Very high108 Ų10877 Ų7758%0.57838%0.384SS*.THydrogen-bonded Turntrans-86.44.8177.6-56.9-45.5000112.4N90 D236 N240N90-D238 PolarHBondContact ND2-OD2 3.23Å; D236-D238 PolarHBondContact O-N 3.43Å; D236-D238 VanDerWaalsContact OD1-C 3.29Å; D236-D238 WeakPolarHBondContact OD1-CA 3.47Å; D236-D238 WeakPolarHBondContact OD1-CB 3.32Å; D236-D238 PolarHBondContact OD1-N 3.5Å; D238-N240 WeakPolarHBondContact CB-ND2 3.47Å; D238-N240 PolarHBondContact O-N 3.48Å
239K97.4Very high97.7Very high161 Ų16170.6 Ų70.670%0.735%0.35SS*.  trans6713-178.6-51177.3179.91770113.9R235 D236 K237R235-K239 PolarHBondContact NH1-O 3.33Å; D236-K239 WeakPolarHBondContact O-CA 3.44Å; D236-K239 PolarHBondContact O-N 3.26Å; D236-K239 PolarHBondContact OD1-N 3.1Å; K237-K239 PolarHBondContact O-N 2.94Å
240N98.4Very high97.7Very high88 Ų8870 Ų7047%0.47134%0.342SS..  trans-73.1140.2175.2-61.3-52.1000110.3R235 D236 D238 H242R235-N240 WeakPolarHBondContact CA-O 3.44Å; D236-N240 PolarHBondContact N-O 2.94Å; D236-N240 PolarHBondContact OD1-N 3.03Å; D238-N240 WeakPolarHBondContact CB-ND2 3.47Å; D238-N240 PolarHBondContact O-N 3.48Å; N240-H242 PolarHBondContact O-CD2 3.35Å; N240-H242 VanDerWaalsContact O-CD2 3.26Å
241F98.2Very high97.8Very high105 Ų10573.5 Ų73.546%0.46136%0.358SS..EExtended strand (participates in β ladder)trans-80.1132.6176.1172.3-93.3000110.4E233 R243E233-F241 HydrophobicContact CB-CE2 3.91Å; E233-F241 HydrophobicContact CB-CZ 4.26Å; E233-F241 HydrophobicContact CG-CE2 4.05Å; E233-F241 HydrophobicContact CG-CZ 3.91Å; F241-R243 HydrophobicContact CE1-CB 4.06Å; F241-R243 HydrophobicContact CZ-CB 4.17Å
242H98.3Very high97.8Very high65 Ų6570.3 Ų70.330%0.30134%0.336SS..EExtended strand (participates in β ladder)trans-127149.5174.6-63.6-88000109.9E233 Y234 D236 N240E233-H242 WeakPolarHBondContact CA-O 3.34Å; Y234-H242 HydrophobicContact CD1-CB 3.98Å; Y234-H242 HydrophobicContact CD2-CB 4.1Å; Y234-H242 HydrophobicContact CE1-CB 3.55Å; Y234-H242 HydrophobicContact CE2-CB 3.66Å; Y234-H242 AromaticContact CE2-CD2 3.66Å; Y234-H242 AromaticContact CE2-CG 3.77Å; Y234-H242 HydrophobicContact CG-CB 4.25Å; Y234-H242 AromaticContact CZ-CG 3.76Å; Y234-H242 PolarHBondContact N-O 3.47Å; Y234-H242 PolarHBondContact O-N 3.32Å; D236-H242 IonicContact OD2-CD2 3.73Å; D236-H242 IonicContact OD2-CE1 3.37Å; D236-H242 IonicContact OD2-NE2 2.83Å; D236-H242 PolarHBondContact OD2-NE2 3.46Å; N240-H242 PolarHBondContact O-CD2 3.35Å; N240-H242 VanDerWaalsContact O-CD2 3.26Å
243R97.7Very high97.8Very high155 Ų15569.8 Ų69.859%0.58533%0.334SS*.EExtended strand (participates in β ladder)trans-134.9131.8172.7-179.4-175.7-76.8177.7-0.5108.9C231 W232 E233 F241C231-R243 VanDerWaalsContact SG-CD 3.54Å; C231-R243 VanDerWaalsContact SG-CG 3.56Å; W232-R243 CarbonylContact O-C 3.48Å; W232-R243 WeakPolarHBondContact O-CA 3.42Å; E233-R243 HydrophobicContact CG-CB 4.34Å; E233-R243 HydrophobicContact CG-CG 4.1Å; E233-R243 IonicContact OE1-CZ 3.61Å; E233-R243 IonicContact OE1-NE 2.87Å; E233-R243 PolarHBondContact OE1-NE 3.28Å; E233-R243 IonicContact OE1-NH2 2.77Å; E233-R243 PolarHBondContact OE1-NH2 3.01Å; F241-R243 HydrophobicContact CE1-CB 4.06Å; F241-R243 HydrophobicContact CZ-CB 4.17Å
244M96.4Very high97.8Very high16 Ų1672 Ų728%0.07934%0.339CS..EExtended strand (participates in β ladder)trans-123.4105.3177.1-169.8-178.2-7200108.6H89 W232 L247 F252 H256H89-M244 WeakPolarHBondContact CE1-CE 3.34Å; W232-M244 HydrophobicContact CE3-CB 4.48Å; W232-M244 HydrophobicContact CE3-SD 4.5Å; W232-M244 PolarHBondContact N-O 2.92Å; W232-M244 PolarHBondContact O-N 3.13Å; M244-L247 HydrophobicContact CG-CD1 3.75Å; M244-L247 HydrophobicContact SD-CD1 4.44Å; M244-F252 HydrophobicContact CG-CD2 4.43Å; M244-F252 HydrophobicContact SD-CD2 3.48Å; M244-F252 WeakPolarHBondContact SD-CD2 3.34Å; M244-F252 HydrophobicContact SD-CE2 3.31Å; M244-F252 WeakPolarHBondContact SD-CE2 3.41Å; M244-F252 HydrophobicContact SD-CZ 4.45Å; M244-H256 HydrophobicContact CE-CB 4.4Å; M244-H256 HydrophobicContact SD-CB 4.26Å; M244-H256 PolarHBondContact SD-CD2 3.07Å
245G94.6Very high97.9Very high29 Ų2975.7 Ų75.730%0.29936%0.357SS..EExtended strand (participates in β ladder)trans145.6168.9-17700000114.1
246P97.3Very high97.9Very high105 Ų10570.2 Ų70.268%0.68234%0.338SS*.EExtended strand (participates in β ladder)cis-73.1131.53.829.8-34.7000112.7I230I230-P246 WeakPolarHBondContact O-CA 3.36Å
247L97.8Very high97.9Very high19 Ų1969.3 Ų69.310%0.09933%0.334CS..EExtended strand (participates in β ladder)trans-134.7144.6175.8-66.8173.5000109.6T229 I230 M244 Q251 F252T229-L247 CarbonylContact C-O 3.54Å; T229-L247 VanDerWaalsContact CA-O 3.25Å; T229-L247 WeakPolarHBondContact CA-O 2.98Å; I230-L247 WeakPolarHBondContact CG1-O 3.21Å; I230-L247 PolarHBondContact N-O 2.93Å; I230-L247 PolarHBondContact O-N 3.46Å; M244-L247 HydrophobicContact CG-CD1 3.75Å; M244-L247 HydrophobicContact SD-CD1 4.44Å; L247-Q251 HydrophobicContact CB-CB 4.29Å; L247-Q251 HydrophobicContact CD2-CB 4.09Å; L247-F252 HydrophobicContact CD1-CB 4.37Å; L247-F252 HydrophobicContact CD1-CD2 4.46Å
248T98.7Very high98Very high48 Ų4866.5 Ų66.529%0.29432%0.321SS..  trans-69.2156162.862.10000110.2D228 T229 Q250 Q251 F252D228-T248 WeakPolarHBondContact O-CA 3.05Å; T229-T248 HydrophobicContact CG2-CG2 4.23Å; T248-Q250 PolarHBondContact O-N 2.92Å; T248-Q251 PolarHBondContact O-N 2.89Å; T248-Q251 VanDerWaalsContact O-N 3.1Å; T248-Q251 WeakPolarHBondContact OG1-CB 2.93Å; T248-Q251 VanDerWaalsContact OG1-CG 3.26Å; T248-Q251 WeakPolarHBondContact OG1-CG 3.36Å; T248-Q251 PolarHBondContact OG1-N 3.24Å; T248-Q251 VanDerWaalsContact OG1-N 3.16Å; T248-Q251 PolarHBondContact OG1-OE1 3.49Å; T248-F252 PolarHBondContact O-N 2.88Å
249P98.7Very high98Very high9 Ų965.8 Ų65.86%0.05832%0.323CS..Hα-helixtrans-51.8-38.1171.8-31.638.1000114.3Y100 Y156 I159 D228 Y253Y100-P249 HydrophobicContact CE1-CB 4.32Å; Y100-P249 HydrophobicContact CE2-CB 4.39Å; Y100-P249 HydrophobicContact CE2-CG 4.14Å; Y100-P249 WeakPolarHBondContact OH-CB 3.49Å; Y100-P249 WeakPolarHBondContact OH-CG 3Å; Y156-P249 WeakPolarHBondContact O-CB 3.09Å; I159-P249 HydrophobicContact CG2-CB 3.58Å; I159-P249 HydrophobicContact CG2-CG 3.68Å; D228-P249 WeakPolarHBondContact O-CD 3.48Å; P249-Y253 PolarHBondContact O-N 3.2Å
250Q98.4Very high98Very high72 Ų7260.8 Ų60.834%0.33630%0.303SS..Hα-helixtrans-66.3-44.1175.8-77.3-172.223.400112.4K155 T248 Y253 R254K155-Q250 PolarHBondContact O-NE2 2.76Å; T248-Q250 PolarHBondContact O-N 2.92Å; Q250-Y253 PolarHBondContact O-N 3.38Å; Q250-R254 WeakPolarHBondContact O-CB 3.16Å; Q250-R254 WeakPolarHBondContact O-CG 3.43Å; Q250-R254 PolarHBondContact O-N 3.12Å
251Q98.7Very high98Very high79 Ų7956.8 Ų56.837%0.36928%0.282SS..Hα-helixtrans-62.4-45.5176.4-76.4166.5-47.500110.7L247 T248 Y253 R254 E255L247-Q251 HydrophobicContact CB-CB 4.29Å; L247-Q251 HydrophobicContact CD2-CB 4.09Å; T248-Q251 PolarHBondContact O-N 2.89Å; T248-Q251 VanDerWaalsContact O-N 3.1Å; T248-Q251 WeakPolarHBondContact OG1-CB 2.93Å; T248-Q251 VanDerWaalsContact OG1-CG 3.26Å; T248-Q251 WeakPolarHBondContact OG1-CG 3.36Å; T248-Q251 PolarHBondContact OG1-N 3.24Å; T248-Q251 VanDerWaalsContact OG1-N 3.16Å; T248-Q251 PolarHBondContact OG1-OE1 3.49Å; Q251-Y253 VanDerWaalsContact C-N 3.3Å; Q251-Y253 PolarHBondContact O-N 2.72Å; Q251-R254 PolarHBondContact O-N 2.66Å; Q251-E255 VanDerWaalsContact O-CB 3.27Å; Q251-E255 WeakPolarHBondContact O-CB 3.37Å; Q251-E255 WeakPolarHBondContact O-CG 3.2Å; Q251-E255 PolarHBondContact O-N 2.87Å
252F98.7Very high98Very high0 Ų053.3 Ų53.30%027%0.268CS..Hα-helixtrans-55.9-45.3176.2177.7-85.5000111.8F85 F96 V158 P160 I230 W232 M244 L247 T248 H256 V257F85-F252 HydrophobicContact CE1-CZ 4.44Å; F85-F252 HydrophobicContact CE2-CE2 4.49Å; F85-F252 AromaticContact CE2-CZ 3.91Å; F85-F252 HydrophobicContact CE2-CZ 3.91Å; F85-F252 HydrophobicContact CZ-CE2 4.12Å; F85-F252 AromaticContact CZ-CZ 3.61Å; F85-F252 HydrophobicContact CZ-CZ 3.61Å; F96-F252 HydrophobicContact CD1-CE1 4.25Å; F96-F252 AromaticContact CE1-CE1 3.69Å; F96-F252 HydrophobicContact CE1-CE1 3.69Å; F96-F252 HydrophobicContact CE1-CZ 4.1Å; V158-F252 HydrophobicContact CG2-CD1 4.22Å; V158-F252 HydrophobicContact CG2-CE1 4.15Å; V158-F252 WeakPolarHBondContact O-CD1 3.09Å; P160-F252 HydrophobicContact CG-CE2 3.9Å; P160-F252 HydrophobicContact CG-CZ 3.77Å; I230-F252 HydrophobicContact CD1-CB 4.18Å; I230-F252 HydrophobicContact CD1-CD2 3.81Å; I230-F252 HydrophobicContact CD1-CE2 4.4Å; I230-F252 HydrophobicContact CD1-CG 4Å; W232-F252 HydrophobicContact CE3-CE2 4.34Å; M244-F252 HydrophobicContact CG-CD2 4.43Å; M244-F252 HydrophobicContact SD-CD2 3.48Å; M244-F252 WeakPolarHBondContact SD-CD2 3.34Å; M244-F252 HydrophobicContact SD-CE2 3.31Å; M244-F252 WeakPolarHBondContact SD-CE2 3.41Å; M244-F252 HydrophobicContact SD-CZ 4.45Å; L247-F252 HydrophobicContact CD1-CB 4.37Å; L247-F252 HydrophobicContact CD1-CD2 4.46Å; T248-F252 PolarHBondContact O-N 2.88Å; F252-H256 WeakPolarHBondContact O-CB 3.16Å; F252-H256 PolarHBondContact O-N 2.92Å; F252-H256 VanDerWaalsContact O-N 3.07Å; F252-V257 HydrophobicContact CD1-CG2 4.17Å; F252-V257 HydrophobicContact CE1-CG2 3.78Å
253Y98.6Very high98Very high2 Ų250.2 Ų50.21%0.00825%0.254CS..Iπ-helixtrans-62.3-54.6174.3170.9-116.3000112.4I153 E154 V158 P249 Q250 Q251 E255 V257 K258I153-Y253 HydrophobicContact CG2-CD1 4.23Å; I153-Y253 HydrophobicContact CG2-CD2 3.74Å; I153-Y253 HydrophobicContact CG2-CE1 3.94Å; I153-Y253 HydrophobicContact CG2-CE2 3.45Å; I153-Y253 VanDerWaalsContact CG2-CE2 3.45Å; I153-Y253 HydrophobicContact CG2-CG 4.15Å; E154-Y253 PolarHBondContact OE1-OH 3.31Å; V158-Y253 HydrophobicContact CG2-CD2 4.19Å; P249-Y253 PolarHBondContact O-N 3.2Å; Q250-Y253 PolarHBondContact O-N 3.38Å; Q251-Y253 VanDerWaalsContact C-N 3.3Å; Q251-Y253 PolarHBondContact O-N 2.72Å; Y253-E255 VanDerWaalsContact C-N 3.35Å; Y253-E255 PolarHBondContact O-N 2.78Å; Y253-V257 HydrophobicContact CD2-CB 3.8Å; Y253-V257 HydrophobicContact CD2-CG1 3.97Å; Y253-V257 HydrophobicContact CE2-CB 4.35Å; Y253-V257 HydrophobicContact CE2-CG1 4.18Å; Y253-V257 CarbonylContact O-C 3.37Å; Y253-V257 WeakPolarHBondContact O-CA 3.49Å; Y253-V257 PolarHBondContact O-N 3.09Å; Y253-K258 HydrophobicContact CD2-CB 4.39Å; Y253-K258 HydrophobicContact CE1-CB 4.08Å; Y253-K258 HydrophobicContact CE1-CD 3.75Å; Y253-K258 HydrophobicContact CE1-CG 4.26Å; Y253-K258 HydrophobicContact CE2-CB 3.88Å; Y253-K258 HydrophobicContact CE2-CG 4.49Å; Y253-K258 WeakPolarHBondContact O-CB 3.5Å; Y253-K258 PolarHBondContact O-N 3.21Å
254R98.4Very high98Very high136 Ų13647 Ų4751%0.51325%0.245SC..Iπ-helixtrans-64.5-36.9-173.5-72178.7-176.1170.27113.2Q250 Q251 P259Q250-R254 WeakPolarHBondContact O-CB 3.16Å; Q250-R254 WeakPolarHBondContact O-CG 3.43Å; Q250-R254 PolarHBondContact O-N 3.12Å; Q251-R254 PolarHBondContact O-N 2.66Å; R254-P259 WeakPolarHBondContact O-CD 3.19Å
255E98.3Very high98.1Very high102 Ų10248.5 Ų48.548%0.47725%0.253SS..Iπ-helixtrans-90.8-32.8-173.3-63.4173.8-152.100112.7Q251 Y253Q251-E255 VanDerWaalsContact O-CB 3.27Å; Q251-E255 WeakPolarHBondContact O-CB 3.37Å; Q251-E255 WeakPolarHBondContact O-CG 3.2Å; Q251-E255 PolarHBondContact O-N 2.87Å; Y253-E255 VanDerWaalsContact C-N 3.35Å; Y253-E255 PolarHBondContact O-N 2.78Å
256H98.3Very high98.3Very high50 Ų5047.5 Ų47.523%0.23124%0.241CC..Iπ-helixtrans-119.1-18.9-170.4-56.9-61.7000115.3F85 M244 F252 L260F85-H256 HydrophobicContact CE2-CB 4.06Å; M244-H256 HydrophobicContact CE-CB 4.4Å; M244-H256 HydrophobicContact SD-CB 4.26Å; M244-H256 PolarHBondContact SD-CD2 3.07Å; F252-H256 WeakPolarHBondContact O-CB 3.16Å; F252-H256 PolarHBondContact O-N 2.92Å; F252-H256 VanDerWaalsContact O-N 3.07Å; H256-L260 VanDerWaalsContact O-CD1 3.3Å; H256-L260 WeakPolarHBondContact O-CD1 3.32Å
257V98.6Very high98.3Very high1 Ų143.1 Ų43.11%0.00621%0.212CC..Iπ-helixtrans-112.4-54.4-176.9-1770000111.7L81 F85 F96 V158 F252 Y253 P259 L260 Y261L81-V257 HydrophobicContact CD2-CG1 4.25Å; F85-V257 HydrophobicContact CD2-CG2 3.93Å; F85-V257 HydrophobicContact CE2-CG2 4.09Å; F96-V257 HydrophobicContact CE1-CG2 3.94Å; F96-V257 HydrophobicContact CZ-CG1 4.24Å; F96-V257 HydrophobicContact CZ-CG2 3.84Å; V158-V257 HydrophobicContact CG2-CB 4.39Å; V158-V257 HydrophobicContact CG2-CG1 4.35Å; V158-V257 HydrophobicContact CG2-CG2 3.87Å; F252-V257 HydrophobicContact CD1-CG2 4.17Å; F252-V257 HydrophobicContact CE1-CG2 3.78Å; Y253-V257 HydrophobicContact CD2-CB 3.8Å; Y253-V257 HydrophobicContact CD2-CG1 3.97Å; Y253-V257 HydrophobicContact CE2-CB 4.35Å; Y253-V257 HydrophobicContact CE2-CG1 4.18Å; Y253-V257 CarbonylContact O-C 3.37Å; Y253-V257 WeakPolarHBondContact O-CA 3.49Å; Y253-V257 PolarHBondContact O-N 3.09Å; V257-P259 VanDerWaalsContact C-N 3.32Å; V257-L260 WeakPolarHBondContact O-CA 3.45Å; V257-L260 WeakPolarHBondContact O-CB 3.44Å; V257-L260 PolarHBondContact O-N 3.47Å; V257-Y261 PolarHBondContact O-N 3.09Å
258K98.6Very high98.4Very high46 Ų4642.4 Ų42.420%0.221%0.209CC..THydrogen-bonded Turntrans-52.9-38.7-177.8-170.1167.9-176141.90114E154 Y253 L260 Y261 N262E154-K258 IonicContact OE1-NZ 2.68Å; E154-K258 PolarHBondContact OE1-NZ 2.76Å; E154-K258 IonicContact OE2-NZ 2.75Å; E154-K258 PolarHBondContact OE2-NZ 2.93Å; Y253-K258 HydrophobicContact CD2-CB 4.39Å; Y253-K258 HydrophobicContact CE1-CB 4.08Å; Y253-K258 HydrophobicContact CE1-CD 3.75Å; Y253-K258 HydrophobicContact CE1-CG 4.26Å; Y253-K258 HydrophobicContact CE2-CB 3.88Å; Y253-K258 HydrophobicContact CE2-CG 4.49Å; Y253-K258 WeakPolarHBondContact O-CB 3.5Å; Y253-K258 PolarHBondContact O-N 3.21Å; K258-L260 PolarHBondContact O-N 2.93Å; K258-Y261 CarbonylContact O-C 3.59Å; K258-N262 VanDerWaalsContact CE-OD1 3.29Å; K258-N262 WeakPolarHBondContact CE-OD1 3.23Å; K258-N262 HydrophobicContact CG-CB 4.23Å; K258-N262 PolarHBondContact O-N 3.46Å
259P98.6Very high98.4Very high93 Ų9340.1 Ų40.160%0.60420%0.195SC*.THydrogen-bonded Turntrans-67.5-19.2176.4-22.235.7000114.2R254 V257R254-P259 WeakPolarHBondContact O-CD 3.19Å; V257-P259 VanDerWaalsContact C-N 3.32Å
260L97.9Very high98.4Very high57 Ų5739.8 Ų39.830%0.29819%0.193SC..THydrogen-bonded Turntrans-98-35.6179.3-52.6178.5000111.8P84 F85 K88 H256 V257 K258P84-L260 HydrophobicContact CB-CB 4.17Å; P84-L260 HydrophobicContact CG-CB 4.48Å; F85-L260 HydrophobicContact CB-CD1 4.45Å; F85-L260 HydrophobicContact CD2-CD1 4.32Å; K88-L260 HydrophobicContact CB-CD1 3.59Å; K88-L260 HydrophobicContact CB-CD2 4.18Å; K88-L260 HydrophobicContact CD-CD2 4.23Å; K88-L260 HydrophobicContact CG-CD1 3.83Å; K88-L260 HydrophobicContact CG-CD2 4.03Å; H256-L260 VanDerWaalsContact O-CD1 3.3Å; H256-L260 WeakPolarHBondContact O-CD1 3.32Å; V257-L260 WeakPolarHBondContact O-CA 3.45Å; V257-L260 WeakPolarHBondContact O-CB 3.44Å; V257-L260 PolarHBondContact O-N 3.47Å; K258-L260 PolarHBondContact O-N 2.93Å
261Y97.9Very high98.4Very high3 Ų336.6 Ų36.61%0.01218%0.178CC..  trans-147.898.3178.6-168.5-83.9000109.1V80 L81 W146 V257 K258 K266 E319V80-Y261 HydrophobicContact CG1-CD2 4.24Å; V80-Y261 HydrophobicContact CG1-CE2 3.4Å; L81-Y261 HydrophobicContact CD1-CD1 3.44Å; L81-Y261 VanDerWaalsContact CD1-CD1 3.44Å; L81-Y261 HydrophobicContact CD1-CE1 3.32Å; L81-Y261 HydrophobicContact CD1-CG 4.29Å; L81-Y261 HydrophobicContact CG-CD1 3.68Å; L81-Y261 HydrophobicContact CG-CE1 4.12Å; L81-Y261 HydrophobicContact CG-CG 4.27Å; W146-Y261 HydrophobicContact CH2-CE1 4.32Å; V257-Y261 PolarHBondContact O-N 3.09Å; K258-Y261 CarbonylContact O-C 3.59Å; Y261-K266 HydrophobicContact CE1-CD 4.37Å; Y261-K266 HydrophobicContact CE1-CG 4.04Å; Y261-K266 HydrophobicContact CE2-CD 4.36Å; Y261-K266 VanDerWaalsContact CE2-CE 3.42Å; Y261-E319 HydrophobicContact CE2-CG 4.15Å
262N98.2Very high98.4Very high32 Ų3233 Ų3317%0.17116%0.161CC..  trans-86.2113.3175.4-178.412.9000109.8K258 Q264 D265 K266K258-N262 VanDerWaalsContact CE-OD1 3.29Å; K258-N262 WeakPolarHBondContact CE-OD1 3.23Å; K258-N262 HydrophobicContact CG-CB 4.23Å; K258-N262 PolarHBondContact O-N 3.46Å; N262-Q264 PolarHBondContact O-N 3.42Å; N262-Q264 WeakPolarHBondContact OD1-CB 3.2Å; N262-Q264 PolarHBondContact OD1-N 2.85Å; N262-Q264 VanDerWaalsContact OD1-N 3.13Å; N262-D265 HydrophobicContact CB-CB 4.37Å; N262-D265 VanDerWaalsContact CB-OD2 3.29Å; N262-D265 WeakPolarHBondContact CB-OD2 3.43Å; N262-D265 VanDerWaalsContact ND2-CG 3.28Å; N262-D265 PolarHBondContact ND2-OD2 3.29Å; N262-D265 PolarHBondContact O-N 2.98Å; N262-D265 VanDerWaalsContact O-N 3.16Å; N262-K266 WeakPolarHBondContact O-CE 3.36Å
263I97.4Very high98.4Very high1 Ų134.6 Ų34.61%0.00517%0.171CC..G310 helixtrans-65.7-24.3-178-156.2174.1000112.2W146 L149 V150 I153 E154 D265 K266W146-I263 HydrophobicContact CH2-CD1 4.12Å; W146-I263 HydrophobicContact CH2-CG1 3.77Å; W146-I263 HydrophobicContact CZ2-CD1 3.95Å; W146-I263 HydrophobicContact CZ2-CG1 3.28Å; L149-I263 HydrophobicContact CB-CD1 4.18Å; V150-I263 HydrophobicContact CG1-CG2 4.23Å; V150-I263 HydrophobicContact CG2-CD1 4.11Å; V150-I263 HydrophobicContact CG2-CG1 4Å; V150-I263 HydrophobicContact CG2-CG2 4.39Å; I153-I263 HydrophobicContact CB-CD1 4.34Å; I153-I263 HydrophobicContact CD1-CD1 3.51Å; I153-I263 HydrophobicContact CG1-CD1 4.46Å; I153-I263 HydrophobicContact CG2-CG2 4.34Å; E154-I263 HydrophobicContact CG-CG2 4.32Å; I263-D265 VanDerWaalsContact C-N 3.31Å; I263-D265 PolarHBondContact O-N 3.2Å; I263-K266 PolarHBondContact O-N 3.23Å
264Q97.7Very high98.4Very high88 Ų8835 Ų3541%0.41117%0.173SC..G310 helixtrans-76.1-16.8178.6-62.4179.9-48.600113.7V150 E154 N262 K266V150-Q264 HydrophobicContact CG1-CG 4.38Å; E154-Q264 VanDerWaalsContact CD-CD 3.49Å; E154-Q264 HydrophobicContact CG-CG 4.1Å; E154-Q264 VanDerWaalsContact OE1-CD 3.3Å; E154-Q264 VanDerWaalsContact OE1-CG 3.27Å; E154-Q264 WeakPolarHBondContact OE1-CG 3.36Å; N262-Q264 PolarHBondContact O-N 3.42Å; N262-Q264 WeakPolarHBondContact OD1-CB 3.2Å; N262-Q264 PolarHBondContact OD1-N 2.85Å; N262-Q264 VanDerWaalsContact OD1-N 3.13Å; Q264-K266 VanDerWaalsContact C-N 3.25Å
265D98.2Very high98.4Very high46 Ų4633.8 Ų33.825%0.24618%0.183CC..G310 helixtrans-84.6-3.2176.3-70.8-37.8000112.6N262 I263 K424N262-D265 HydrophobicContact CB-CB 4.37Å; N262-D265 VanDerWaalsContact CB-OD2 3.29Å; N262-D265 WeakPolarHBondContact CB-OD2 3.43Å; N262-D265 VanDerWaalsContact ND2-CG 3.28Å; N262-D265 PolarHBondContact ND2-OD2 3.29Å; N262-D265 PolarHBondContact O-N 2.98Å; N262-D265 VanDerWaalsContact O-N 3.16Å; I263-D265 VanDerWaalsContact C-N 3.31Å; I263-D265 PolarHBondContact O-N 3.2Å; D265-K424 HydrophobicContact CB-CD 4.4Å; D265-K424 WeakPolarHBondContact O-CB 3.37Å; D265-K424 PolarHBondContact O-N 3.11Å; D265-K424 WeakPolarHBondContact OD1-CE 3.42Å; D265-K424 IonicContact OD1-NZ 3.28Å; D265-K424 PolarHBondContact OD1-NZ 3.41Å
266K98.6Very high98.3Very high9 Ų934.3 Ų34.34%0.03919%0.185CC..EExtended strand (participates in β ladder)trans-93.9138.8-177.1-46.1-55.1173.1177.60110.8W146 Y261 N262 I263 Q264 E319 V421 V422 D423W146-K266 HydrophobicContact CH2-CB 4.49Å; W146-K266 HydrophobicContact CH2-CG 4.41Å; W146-K266 HydrophobicContact CZ2-CB 3.54Å; W146-K266 HydrophobicContact CZ2-CG 3.75Å; Y261-K266 HydrophobicContact CE1-CD 4.37Å; Y261-K266 HydrophobicContact CE1-CG 4.04Å; Y261-K266 HydrophobicContact CE2-CD 4.36Å; Y261-K266 VanDerWaalsContact CE2-CE 3.42Å; N262-K266 WeakPolarHBondContact O-CE 3.36Å; I263-K266 PolarHBondContact O-N 3.23Å; Q264-K266 VanDerWaalsContact C-N 3.25Å; K266-E319 IonicContact NZ-OE1 2.76Å; K266-E319 PolarHBondContact NZ-OE1 3.16Å; K266-E319 IonicContact NZ-OE2 3.21Å; K266-E319 PolarHBondContact NZ-OE2 2.78Å; K266-V421 HydrophobicContact CB-CG1 3.66Å; K266-V422 CarbonylContact C-O 3.59Å; K266-V422 WeakPolarHBondContact CA-O 3.33Å; K266-D423 HydrophobicContact CD-CB 4.09Å; K266-D423 IonicContact NZ-OD2 2.81Å; K266-D423 PolarHBondContact NZ-OD2 3.07Å
267V98.7Very high98.3Very high13 Ų1332.5 Ų32.58%0.07918%0.177CC..EExtended strand (participates in β ladder)trans-116.5129.4-177.3179.40000109L269 V421 V422 K424 L427 L432 M435V267-L269 HydrophobicContact CG1-CD2 4.11Å; V267-V421 WeakPolarHBondContact O-CA 3.37Å; V267-V422 PolarHBondContact N-O 2.8Å; V267-V422 PolarHBondContact O-N 3.5Å; V267-K424 HydrophobicContact CG2-CB 3.94Å; V267-L427 HydrophobicContact CB-CD1 3.57Å; V267-L427 HydrophobicContact CG1-CD1 3.65Å; V267-L427 HydrophobicContact CG2-CD1 3.99Å; V267-L432 HydrophobicContact CG2-CD2 3.99Å; V267-M435 HydrophobicContact CG1-CG 4.17Å; V267-M435 HydrophobicContact CG1-SD 4.02Å
268C98.7Very high98.3Very high3 Ų335.9 Ų35.92%0.0220%0.199CC..EExtended strand (participates in β ladder)trans-84.1111.6174.6169.50000110.3W146 N300 E419 V421W146-C268 HydrophobicContact CB-CB 4.47Å; C268-N300 WeakPolarHBondContact O-CB 3.5Å; C268-N300 PolarHBondContact O-N 3.32Å; C268-E419 VanDerWaalsContact SG-CD 3.57Å; C268-E419 VanDerWaalsContact SG-CG 3.59Å; C268-E419 PolarHBondContact SG-OE1 3.44Å; C268-V421 HydrophobicContact CB-CG2 4.24Å
269L98.9Very high98.3Very high0 Ų038.3 Ų38.30%021%0.208CC..EExtended strand (participates in β ladder)trans-99.7134.7170.2-59.7-173.4000109.7V267 N300 Q302 L306 L307 A310 E419 V420 L427 V431V267-L269 HydrophobicContact CG1-CD2 4.11Å; L269-N300 WeakPolarHBondContact CA-O 3.36Å; L269-N300 HydrophobicContact CD2-CB 3.87Å; L269-Q302 HydrophobicContact CD2-CG 4.17Å; L269-L306 HydrophobicContact CD1-CD2 4.14Å; L269-L307 HydrophobicContact CB-CD1 4.19Å; L269-L307 HydrophobicContact CB-CG 3.95Å; L269-L307 HydrophobicContact CD1-CG 4.46Å; L269-A310 HydrophobicContact CD1-CB 4.44Å; L269-E419 CarbonylContact O-C 3.57Å; L269-E419 VanDerWaalsContact O-CA 3.27Å; L269-E419 WeakPolarHBondContact O-CA 3.33Å; L269-V420 HydrophobicContact CB-CG2 4.03Å; L269-V420 HydrophobicContact CD1-CG2 4.47Å; L269-V420 PolarHBondContact N-O 3.41Å; L269-V420 PolarHBondContact O-N 3.22Å; L269-L427 HydrophobicContact CD1-CD2 3.68Å; L269-L427 HydrophobicContact CD2-CD1 4.13Å; L269-L427 HydrophobicContact CG-CD1 4.44Å; L269-L427 HydrophobicContact CG-CD2 4.44Å; L269-V431 HydrophobicContact CD2-CG1 3.86Å
270V98.9Very high98.3Very high3 Ų335.1 Ų35.12%0.01819%0.192CC..EExtended strand (participates in β ladder)trans-116.1157.3171.2-57.20000111.6Y299 N300 N301 Q302 Y418 E419 M448V270-Y299 HydrophobicContact CG1-CD1 3.56Å; V270-Y299 HydrophobicContact CG1-CD2 4.47Å; V270-Y299 HydrophobicContact CG1-CE1 4.26Å; V270-Y299 HydrophobicContact CG1-CG 3.69Å; V270-Y299 HydrophobicContact CG2-CG 4.42Å; V270-N300 PolarHBondContact N-O 2.98Å; V270-N301 HydrophobicContact CG2-CB 3.95Å; V270-N301 WeakPolarHBondContact O-CA 3.39Å; V270-N301 PolarHBondContact O-OD1 3.45Å; V270-Q302 PolarHBondContact O-N 3.3Å; V270-Y418 CarbonylContact C-O 3.58Å; V270-Y418 WeakPolarHBondContact CA-O 3.48Å; V270-Y418 WeakPolarHBondContact CB-O 3.46Å; V270-E419 HydrophobicContact CG1-CB 4.22Å; V270-E419 HydrophobicContact CG1-CG 3.99Å; V270-M448 HydrophobicContact CB-CE 3.74Å; V270-M448 HydrophobicContact CG1-CE 4.02Å; V270-M448 HydrophobicContact CG2-CE 4.14Å
271N98.8Very high98.4Very high4 Ų436.9 Ų36.92%0.02120%0.197CC..  trans-118.796.5164.4178.5-112.5000109.7P273 Y279 Q302 I304 L307 K358 Y418N271-P273 WeakPolarHBondContact O-CD 3.41Å; N271-Y279 WeakPolarHBondContact ND2-CE1 3.3Å; N271-Y279 PolarHBondContact ND2-OH 2.8Å; N271-Y279 VanDerWaalsContact ND2-OH 3.08Å; N271-Q302 PolarHBondContact ND2-O 2.85Å; N271-I304 HydrophobicContact CB-CB 4.37Å; N271-I304 HydrophobicContact CB-CD1 3.78Å; N271-I304 PolarHBondContact ND2-N 2.87Å; N271-L307 HydrophobicContact CB-CD1 4.39Å; N271-L307 HydrophobicContact CB-CD2 3.9Å; N271-K358 PolarHBondContact OD1-NZ 3.02Å; N271-Y418 PolarHBondContact N-O 2.84Å
272D98.8Very high98.4Very high3 Ų337 Ų372%0.01620%0.197CC..  trans-106.899.7170.2-178.3-0.4000109.2R274 N277 N301 M448D272-R274 VanDerWaalsContact CG-NE 3.32Å; D272-R274 PolarHBondContact O-N 3.32Å; D272-R274 VanDerWaalsContact OD1-CB 3.23Å; D272-R274 WeakPolarHBondContact OD1-CB 3.37Å; D272-R274 WeakPolarHBondContact OD1-CG 3.36Å; D272-R274 IonicContact OD1-CZ 3.23Å; D272-R274 PolarHBondContact OD1-N 2.91Å; D272-R274 VanDerWaalsContact OD1-N 3.08Å; D272-R274 IonicContact OD1-NE 2.8Å; D272-R274 PolarHBondContact OD1-NE 3.03Å; D272-R274 IonicContact OD1-NH2 2.72Å; D272-R274 IonicContact OD2-CZ 3.03Å; D272-R274 IonicContact OD2-NE 2.86Å; D272-R274 PolarHBondContact OD2-NE 3.12Å; D272-R274 IonicContact OD2-NH2 3.04Å; D272-R274 PolarHBondContact OD2-NH2 2.7Å; D272-N277 PolarHBondContact OD2-ND2 3.38Å; D272-N301 PolarHBondContact N-OD1 3.21Å; D272-N301 PolarHBondContact O-ND2 3.21Å; D272-N301 PolarHBondContact O-OD1 3.21Å; D272-M448 HydrophobicContact CB-CE 4.19Å; D272-M448 HydrophobicContact CB-CG 4.25Å; D272-M448 HydrophobicContact CB-SD 4.05Å
273P98.6Very high98.4Very high34 Ų3435.8 Ų35.822%0.22119%0.191CC..  trans-82.27.4-177.734.7-38.3000113.4N271 K358 A359 L362N271-P273 WeakPolarHBondContact O-CD 3.41Å; P273-K358 HydrophobicContact CG-CB 3.93Å; P273-K358 HydrophobicContact CG-CD 4.01Å; P273-K358 HydrophobicContact CG-CG 3.79Å; P273-A359 HydrophobicContact CB-CB 4.28Å; P273-A359 HydrophobicContact CG-CB 4.05Å; P273-A359 WeakPolarHBondContact O-CB 3.44Å; P273-L362 HydrophobicContact CG-CD1 4.36Å
274R98.7Very high98.5Very high11 Ų1135.9 Ų35.94%0.04219%0.191CC..  trans-61.3130.2179.1-69.8179.5-66.8172.7-1.5109.8D272 Q276 N277 L362 I363 D446 M448D272-R274 VanDerWaalsContact CG-NE 3.32Å; D272-R274 PolarHBondContact O-N 3.32Å; D272-R274 VanDerWaalsContact OD1-CB 3.23Å; D272-R274 WeakPolarHBondContact OD1-CB 3.37Å; D272-R274 WeakPolarHBondContact OD1-CG 3.36Å; D272-R274 IonicContact OD1-CZ 3.23Å; D272-R274 PolarHBondContact OD1-N 2.91Å; D272-R274 VanDerWaalsContact OD1-N 3.08Å; D272-R274 IonicContact OD1-NE 2.8Å; D272-R274 PolarHBondContact OD1-NE 3.03Å; D272-R274 IonicContact OD1-NH2 2.72Å; D272-R274 IonicContact OD2-CZ 3.03Å; D272-R274 IonicContact OD2-NE 2.86Å; D272-R274 PolarHBondContact OD2-NE 3.12Å; D272-R274 IonicContact OD2-NH2 3.04Å; D272-R274 PolarHBondContact OD2-NH2 2.7Å; R274-Q276 PolarHBondContact O-N 3.19Å; R274-N277 PolarHBondContact NE-ND2 3.44Å; R274-N277 PolarHBondContact NH2-ND2 3.26Å; R274-N277 PolarHBondContact O-N 3.32Å; R274-L362 HydrophobicContact CG-CB 4.16Å; R274-L362 HydrophobicContact CG-CD1 4.2Å; R274-I363 HydrophobicContact CG-CD1 4.2Å; R274-I363 HydrophobicContact CG-CG1 3.9Å; R274-D446 IonicContact CZ-OD1 3.92Å; R274-D446 IonicContact CZ-OD2 3.8Å; R274-D446 IonicContact NH1-OD1 2.67Å; R274-D446 PolarHBondContact NH1-OD1 2.89Å; R274-D446 IonicContact NH1-OD2 3.24Å; R274-D446 PolarHBondContact NH1-OD2 2.86Å; R274-D446 IonicContact NH2-OD1 3.5Å; R274-D446 PolarHBondContact NH2-OD1 3.48Å; R274-D446 IonicContact NH2-OD2 2.65Å; R274-D446 PolarHBondContact NH2-OD2 3.23Å; R274-M448 VanDerWaalsContact NH2-CG 3.34Å
275P97.9Very high98.5Very high111 Ų11131.9 Ų31.972%0.72117%0.173SC*.THydrogen-bonded Turntrans-57.2-29.8-171.3-28.535.2000115.3N277P275-N277 VanDerWaalsContact C-N 3.25Å; P275-N277 PolarHBondContact O-N 3.05Å
276Q97.3Very high98.5Very high113 Ų11331.8 Ų31.853%0.52817%0.171SC..THydrogen-bonded Turntrans-74.6-12.3178.169.8-85.521.900114.2R274 P278R274-Q276 PolarHBondContact O-N 3.19Å; Q276-P278 WeakPolarHBondContact O-CD 3.34Å
277N98.1Very high98.5Very high12 Ų1232.6 Ų32.66%0.06417%0.174CC..SBendtrans-113.279.4-176.8-66.1-17.3000109.7D272 R274 P275 Y283 N301D272-N277 PolarHBondContact OD2-ND2 3.38Å; R274-N277 PolarHBondContact NE-ND2 3.44Å; R274-N277 PolarHBondContact NH2-ND2 3.26Å; R274-N277 PolarHBondContact O-N 3.32Å; P275-N277 VanDerWaalsContact C-N 3.25Å; P275-N277 PolarHBondContact O-N 3.05Å; N277-Y283 WeakPolarHBondContact CA-OH 3.41Å; N277-Y283 HydrophobicContact CB-CE1 3.98Å; N277-N301 PolarHBondContact O-ND2 2.78Å
278P98.2Very high98.5Very high71 Ų7133.4 Ų33.446%0.46118%0.178SC..  trans-58.9148.9179.325-35.1000112.2Q276 K281 Y283Q276-P278 WeakPolarHBondContact O-CD 3.34Å; P278-K281 HydrophobicContact CG-CG 3.99Å; P278-Y283 WeakPolarHBondContact CD-OH 3.48Å; P278-Y283 VanDerWaalsContact N-OH 3.1Å; P278-Y283 PolarHBondContact O-OH 3.33Å
279Y98.7Very high98.4Very high97 Ų9733.7 Ų33.738%0.3818%0.182SC..SBendtrans-65.7161.8169.6-58.2-45000111.7N271 K281 N301 Q302 P303N271-Y279 WeakPolarHBondContact ND2-CE1 3.3Å; N271-Y279 PolarHBondContact ND2-OH 2.8Å; N271-Y279 VanDerWaalsContact ND2-OH 3.08Å; Y279-K281 VanDerWaalsContact C-N 3.26Å; Y279-K281 PolarHBondContact O-N 3.02Å; Y279-N301 CarbonylContact C-O 3.47Å; Y279-N301 WeakPolarHBondContact CA-O 3.33Å; Y279-Q302 WeakPolarHBondContact CE1-O 3.46Å; Y279-P303 HydrophobicContact CD2-CB 4.24Å; Y279-P303 HydrophobicContact CD2-CG 3.66Å; Y279-P303 HydrophobicContact CE2-CB 4.13Å; Y279-P303 HydrophobicContact CE2-CG 4.07Å; Y279-P303 HydrophobicContact CG-CG 4.04Å
280G98.6Very high98.4Very high26 Ų2633.7 Ų33.727%0.26818%0.182SC..SBendtrans7221-177.200000113.6N301 Q437G280-N301 PolarHBondContact N-O 3.1Å; G280-Q437 PolarHBondContact O-NE2 3.19Å; G280-Q437 VanDerWaalsContact O-NE2 3.09Å
281K98.8Very high98.4Very high95 Ų9534.4 Ų34.441%0.41319%0.185SC..EExtended strand (participates in β ladder)trans-123.8148.4178.4-67.1-58.1-175.7-176.40111.3P278 Y279 Y283 N301 V434P278-K281 HydrophobicContact CG-CG 3.99Å; Y279-K281 VanDerWaalsContact C-N 3.26Å; Y279-K281 PolarHBondContact O-N 3.02Å; K281-Y283 HydrophobicContact CB-CD2 4.41Å; K281-Y283 HydrophobicContact CB-CE2 3.52Å; K281-Y283 WeakPolarHBondContact O-CD2 3.32Å; K281-Y283 WeakPolarHBondContact O-CE2 3.32Å; K281-N301 PolarHBondContact O-N 2.85Å; K281-N301 VanDerWaalsContact O-N 3.07Å; K281-V434 VanDerWaalsContact C-CG1 3.41Å
282L98.8Very high98.3Very high4 Ų436.9 Ų36.92%0.02120%0.2CC..EExtended strand (participates in β ladder)trans-92.2133175.5-164.367.4000109.9L298 Y299 V434 M435 Q437 A439 V440L282-L298 HydrophobicContact CD1-CB 4.2Å; L282-L298 HydrophobicContact CD2-CD1 4.37Å; L282-L298 HydrophobicContact CD2-CD2 4.14Å; L282-L298 HydrophobicContact CG-CD2 4.33Å; L282-Y299 WeakPolarHBondContact CA-O 3.4Å; L282-V434 HydrophobicContact CB-CG1 4.05Å; L282-V434 HydrophobicContact CD1-CG1 4.49Å; L282-M435 HydrophobicContact CD1-CE 4.32Å; L282-M435 HydrophobicContact CD1-SD 3.71Å; L282-Q437 HydrophobicContact CB-CB 4.14Å; L282-Q437 VanDerWaalsContact CD2-O 3.28Å; L282-Q437 WeakPolarHBondContact CD2-O 3.18Å; L282-A439 HydrophobicContact CB-CB 4.42Å; L282-A439 HydrophobicContact CD2-CB 4.03Å; L282-A439 HydrophobicContact CG-CB 3.99Å; L282-A439 CarbonylContact O-C 3.59Å; L282-A439 WeakPolarHBondContact O-CA 3.4Å; L282-V440 PolarHBondContact O-N 2.92Å
283Y98.8Very high98.3Very high8 Ų840.8 Ų40.83%0.03124%0.241CC..EExtended strand (participates in β ladder)trans-123.7155.8177.4-59.5-96.1000110.6N277 P278 K281 L298 Y299 N301 V440 L442N277-Y283 WeakPolarHBondContact CA-OH 3.41Å; N277-Y283 HydrophobicContact CB-CE1 3.98Å; P278-Y283 WeakPolarHBondContact CD-OH 3.48Å; P278-Y283 VanDerWaalsContact N-OH 3.1Å; P278-Y283 PolarHBondContact O-OH 3.33Å; K281-Y283 HydrophobicContact CB-CD2 4.41Å; K281-Y283 HydrophobicContact CB-CE2 3.52Å; K281-Y283 WeakPolarHBondContact O-CD2 3.32Å; K281-Y283 WeakPolarHBondContact O-CE2 3.32Å; Y283-L298 WeakPolarHBondContact O-CA 3.3Å; Y283-Y299 PolarHBondContact N-O 3.49Å; Y283-Y299 PolarHBondContact O-N 2.99Å; Y283-N301 HydrophobicContact CD2-CB 3.8Å; Y283-N301 HydrophobicContact CE2-CB 3.51Å; Y283-V440 CarbonylContact C-O 3.5Å; Y283-V440 WeakPolarHBondContact CA-O 3.29Å; Y283-V440 HydrophobicContact CD1-CB 3.73Å; Y283-V440 HydrophobicContact CD1-CG1 4.08Å; Y283-V440 HydrophobicContact CE1-CB 3.96Å; Y283-V440 HydrophobicContact CE1-CG1 4.15Å; Y283-V440 HydrophobicContact CE1-CG2 4.36Å; Y283-L442 HydrophobicContact CD1-CD1 4.2Å; Y283-L442 HydrophobicContact CD1-CD2 3.99Å; Y283-L442 HydrophobicContact CD1-CG 4.14Å
284S98.6Very high98.2Very high2 Ų240.3 Ų40.31%0.01424%0.243CC..EExtended strand (participates in β ladder)trans-139.4160167.3-166.90000108.2T297 V440 V441 L442S284-T297 WeakPolarHBondContact CA-O 3.42Å; S284-T297 VanDerWaalsContact CB-O 3.32Å; S284-T297 WeakPolarHBondContact CB-O 3.2Å; S284-T297 PolarHBondContact OG-O 3.46Å; S284-V440 PolarHBondContact N-O 3.17Å; S284-V441 CarbonylContact O-C 3.59Å; S284-V441 WeakPolarHBondContact O-CA 3.35Å; S284-L442 PolarHBondContact O-N 2.74Å
285V98.7Very high98.2Very high5 Ų544.3 Ų44.33%0.0326%0.258CS..EExtended strand (participates in β ladder)trans-112.6130177.6178.60000108.4F287 L288 Y299 L442 P443 D446V285-F287 PolarHBondContact O-N 3.39Å; V285-L288 HydrophobicContact CB-CB 3.66Å; V285-L288 HydrophobicContact CB-CD2 3.64Å; V285-L288 HydrophobicContact CB-CG 4.32Å; V285-L288 HydrophobicContact CG1-CB 3.87Å; V285-L288 HydrophobicContact CG1-CD2 4.17Å; V285-L288 HydrophobicContact CG2-CD2 3.93Å; V285-L288 WeakPolarHBondContact O-CB 3.37Å; V285-L288 PolarHBondContact O-N 2.95Å; V285-L288 VanDerWaalsContact O-N 3.16Å; V285-Y299 HydrophobicContact CG2-CD2 4.46Å; V285-Y299 HydrophobicContact CG2-CE2 3.89Å; V285-L442 HydrophobicContact CG2-CB 4.28Å; V285-L442 HydrophobicContact CG2-CD1 4.37Å; V285-P443 WeakPolarHBondContact CG1-O 3.43Å; V285-D446 HydrophobicContact CG1-CB 4.44Å
286E98.5Very high98.1Very high43 Ų4346.1 Ų46.120%0.20125%0.25CS..THydrogen-bonded Turntrans-57133.9-179.7-159.4-169.9-166.300110.8R123 L288 V441 L442 A444R123-E286 IonicContact CZ-OE1 2.96Å; R123-E286 VanDerWaalsContact CZ-OE1 3.28Å; R123-E286 IonicContact NH1-OE1 3.75Å; R123-E286 PolarHBondContact NH1-OE1 2.99Å; R123-E286 IonicContact NH2-OE1 2.7Å; R123-E286 PolarHBondContact NH2-OE1 3.46Å; E286-L288 PolarHBondContact O-N 3.25Å; E286-V441 HydrophobicContact CB-CG1 3.9Å; E286-V441 HydrophobicContact CG-CG1 4.32Å; E286-L442 WeakPolarHBondContact CB-O 3.41Å; E286-L442 PolarHBondContact N-O 3.5Å; E286-A444 HydrophobicContact CB-CB 4.3Å; E286-A444 WeakPolarHBondContact O-CA 3.39Å; E286-A444 WeakPolarHBondContact O-CB 3.36Å
287F98.1Very high98.2Very high26 Ų2640.8 Ų40.811%0.11423%0.226CC..THydrogen-bonded Turntrans55.615-177-59.1-73.3000116.5Y112 A116 E119 T120 L131 L135 V285 G289Y112-F287 WeakPolarHBondContact CE1-O 3.4Å; Y112-F287 WeakPolarHBondContact OH-CA 3.29Å; A116-F287 HydrophobicContact CB-CD1 3.55Å; A116-F287 HydrophobicContact CB-CE1 3.74Å; E119-F287 HydrophobicContact CB-CE1 4.45Å; E119-F287 HydrophobicContact CG-CZ 4.43Å; E119-F287 VanDerWaalsContact OE1-CZ 3.28Å; E119-F287 WeakPolarHBondContact OE1-CZ 3.17Å; E119-F287 WeakPolarHBondContact OE2-CE1 3.47Å; T120-F287 HydrophobicContact CG2-CE1 4.41Å; T120-F287 HydrophobicContact CG2-CE2 3.99Å; T120-F287 HydrophobicContact CG2-CZ 3.72Å; L131-F287 HydrophobicContact CD1-CD2 3.9Å; L131-F287 HydrophobicContact CD1-CE2 4.15Å; L131-F287 HydrophobicContact CD2-CE2 3.94Å; L135-F287 HydrophobicContact CD1-CD2 4.41Å; L135-F287 HydrophobicContact CD1-CG 4.42Å; L135-F287 HydrophobicContact CD2-CB 3.75Å; L135-F287 HydrophobicContact CD2-CG 4.19Å; V285-F287 PolarHBondContact O-N 3.39Å; F287-G289 PolarHBondContact O-N 3.25Å
288L98.1Very high98.2Very high30 Ų3041.9 Ų41.916%0.15723%0.231CC..  trans-87.779.1171.6-173.167.2000110.7Q145 M148 V285 E286 T297 Y299 G449Q145-L288 HydrophobicContact CG-CD1 4.41Å; Q145-L288 HydrophobicContact CG-CD2 4.02Å; Q145-L288 HydrophobicContact CG-CG 4.34Å; M148-L288 HydrophobicContact CE-CD1 3.62Å; M148-L288 HydrophobicContact CE-CG 3.71Å; V285-L288 HydrophobicContact CB-CB 3.66Å; V285-L288 HydrophobicContact CB-CD2 3.64Å; V285-L288 HydrophobicContact CB-CG 4.32Å; V285-L288 HydrophobicContact CG1-CB 3.87Å; V285-L288 HydrophobicContact CG1-CD2 4.17Å; V285-L288 HydrophobicContact CG2-CD2 3.93Å; V285-L288 WeakPolarHBondContact O-CB 3.37Å; V285-L288 PolarHBondContact O-N 2.95Å; V285-L288 VanDerWaalsContact O-N 3.16Å; E286-L288 PolarHBondContact O-N 3.25Å; L288-T297 HydrophobicContact CD2-CG2 3.92Å; L288-T297 HydrophobicContact CG-CG2 4.5Å; L288-T297 PolarHBondContact O-OG1 3.5Å; L288-Y299 HydrophobicContact CD2-CE2 4.45Å; L288-Y299 WeakPolarHBondContact CD2-OH 3.41Å; L288-G449 VanDerWaalsContact CD1-O 3.29Å; L288-G449 WeakPolarHBondContact CD1-O 3.09Å; L288-G449 VanDerWaalsContact CD2-CA 3.44Å
289G96.6Very high98.2Very high9 Ų938.6 Ų38.69%0.09321%0.21CC..  trans-148.4167.1178.300000112Y112 F287Y112-G289 WeakPolarHBondContact CD1-O 3.12Å; F287-G289 PolarHBondContact O-N 3.25Å
290N98.3Very high98.2Very high0 Ų034 Ų340%019%0.192CC..SBendtrans-126.50.7174.872.6-25.2000113.3D105 E108 R109 M148 N151 L152D105-N290 WeakPolarHBondContact OD1-CB 3.36Å; D105-N290 PolarHBondContact OD1-ND2 3.19Å; E108-N290 CarbonylContact C-O 3.5Å; E108-N290 WeakPolarHBondContact CB-O 3.49Å; R109-N290 HydrophobicContact CB-CB 4.32Å; R109-N290 PolarHBondContact N-O 2.8Å; R109-N290 VanDerWaalsContact N-O 3.08Å; M148-N290 WeakPolarHBondContact CA-OD1 3.38Å; M148-N290 HydrophobicContact CB-CB 4.24Å; M148-N290 WeakPolarHBondContact CB-ND2 3.06Å; M148-N290 HydrophobicContact CG-CB 3.98Å; M148-N290 PolarHBondContact O-ND2 2.88Å; M148-N290 VanDerWaalsContact O-ND2 3.16Å; M148-N290 HydrophobicContact SD-CB 4.06Å; N151-N290 PolarHBondContact ND2-OD1 3.39Å; L152-N290 WeakPolarHBondContact CG-ND2 3.48Å
291M98.7Very high98.3Very high18 Ų1832.8 Ų32.89%0.08918%0.179CC..SBendtrans-148.8126.7-174.4-173178.2-67.400110.7E108 N151 L152 K155 Y156 G293 G294E108-M291 HydrophobicContact CG-CE 4.03Å; N151-M291 HydrophobicContact CB-CB 4.24Å; N151-M291 HydrophobicContact CB-CE 3.9Å; N151-M291 HydrophobicContact CB-SD 4.02Å; N151-M291 WeakPolarHBondContact O-CE 3.36Å; L152-M291 HydrophobicContact CD2-CE 4.4Å; K155-M291 HydrophobicContact CB-CE 4.08Å; K155-M291 HydrophobicContact CD-CE 3.57Å; K155-M291 HydrophobicContact CD-SD 3.69Å; K155-M291 HydrophobicContact CG-CE 4.43Å; Y156-M291 HydrophobicContact CE2-CE 4.01Å; M291-G293 PolarHBondContact O-N 2.77Å; M291-G294 PolarHBondContact O-N 3.08Å; M291-G294 VanDerWaalsContact O-N 3.07Å
292V98.6Very high98.3Very high56 Ų5629 Ų2934%0.33916%0.163SC..THydrogen-bonded Turntrans-65.3126.8177.2179.80000109.4Y111 Y112 H115 G294Y111-V292 HydrophobicContact CD1-CB 4.05Å; Y111-V292 HydrophobicContact CD1-CG2 3.55Å; Y111-V292 HydrophobicContact CE1-CB 3.87Å; Y111-V292 HydrophobicContact CE1-CG1 4.48Å; Y111-V292 HydrophobicContact CE1-CG2 3.69Å; Y111-V292 HydrophobicContact CG-CG2 4.39Å; Y112-V292 HydrophobicContact CD2-CG2 4.34Å; H115-V292 HydrophobicContact CB-CG2 3.99Å; V292-G294 PolarHBondContact O-N 2.82Å
293G97.7Very high98.2Very high85 Ų8531.4 Ų31.488%0.87618%0.178SC*.THydrogen-bonded Turntrans696.9-175.400000114.6M291M291-G293 PolarHBondContact O-N 2.77Å
294G97.8Very high98.2Very high25 Ų2532.7 Ų32.726%0.25819%0.185SC..SBendtrans-72.8178.617300000112.7M291 V292 R296M291-G294 PolarHBondContact O-N 3.08Å; M291-G294 VanDerWaalsContact O-N 3.07Å; V292-G294 PolarHBondContact O-N 2.82Å; G294-R296 PolarHBondContact O-N 3.39Å
295R96.9Very high98.2Very high95 Ų9535.9 Ų35.936%0.35820%0.2SC..PPolyproline II helixtrans-60.5137.5170.4-65.8171.960129.1-4.3109.5D147 V150 N151D147-R295 HydrophobicContact CB-CB 4.47Å; D147-R295 IonicContact OD1-CZ 2.96Å; D147-R295 IonicContact OD1-NE 2.84Å; D147-R295 PolarHBondContact OD1-NE 3.36Å; D147-R295 VanDerWaalsContact OD1-NE 3.14Å; D147-R295 IonicContact OD1-NH2 3.14Å; D147-R295 PolarHBondContact OD1-NH2 3.35Å; V150-R295 VanDerWaalsContact CG1-CD 3.48Å; N151-R295 PolarHBondContact ND2-O 3.36Å; N151-R295 VanDerWaalsContact ND2-O 3.13Å; N151-R295 VanDerWaalsContact OD1-CB 3.29Å; N151-R295 WeakPolarHBondContact OD1-CB 3.42Å; N151-R295 PolarHBondContact OD1-N 3.07Å
296R97.2Very high98.2Very high148 Ų14837.6 Ų37.656%0.55821%0.209SC*.PPolyproline II helixtrans-70.6148.5169.2-56.8-179.586.8-179.36.2108.4G294 L298G294-R296 PolarHBondContact O-N 3.39Å; R296-L298 HydrophobicContact CB-CD2 4.38Å; R296-L298 PolarHBondContact O-N 3.26Å
297T98.4Very high98.2Very high2 Ų235.5 Ų35.51%0.01220%0.199CC..PPolyproline II helixtrans-69.1118.7169-54.90000108.8Q145 S284 L288 Y299Q145-T297 HydrophobicContact CB-CG2 3.8Å; Q145-T297 HydrophobicContact CG-CG2 4.02Å; S284-T297 WeakPolarHBondContact CA-O 3.42Å; S284-T297 VanDerWaalsContact CB-O 3.32Å; S284-T297 WeakPolarHBondContact CB-O 3.2Å; S284-T297 PolarHBondContact OG-O 3.46Å; L288-T297 HydrophobicContact CD2-CG2 3.92Å; L288-T297 HydrophobicContact CG-CG2 4.5Å; L288-T297 PolarHBondContact O-OG1 3.5Å; T297-Y299 HydrophobicContact CG2-CD1 4.26Å; T297-Y299 HydrophobicContact CG2-CE1 3.51Å; T297-Y299 HydrophobicContact CG2-CE2 4.31Å
298L98.5Very high98.3Very high34 Ų3434.5 Ų34.518%0.17820%0.195CC..  trans-119.8130.9-175.7-66.4179.8000111.2D147 L282 Y283 R296 M435 A439D147-L298 PolarHBondContact OD2-N 2.97Å; L282-L298 HydrophobicContact CD1-CB 4.2Å; L282-L298 HydrophobicContact CD2-CD1 4.37Å; L282-L298 HydrophobicContact CD2-CD2 4.14Å; L282-L298 HydrophobicContact CG-CD2 4.33Å; Y283-L298 WeakPolarHBondContact O-CA 3.3Å; R296-L298 HydrophobicContact CB-CD2 4.38Å; R296-L298 PolarHBondContact O-N 3.26Å; L298-M435 HydrophobicContact CB-CE 4.21Å; L298-M435 HydrophobicContact CD1-CE 4.22Å; L298-A439 HydrophobicContact CD2-CB 3.9Å
299Y98.7Very high98.3Very high3 Ų335.3 Ų35.31%0.01220%0.199CC..EExtended strand (participates in β ladder)trans-119.6116.1-178.9-61.8-35.4000110.8Q145 V270 L282 Y283 V285 L288 T297 N301 M448Q145-Y299 WeakPolarHBondContact CG-OH 3.45Å; Q145-Y299 PolarHBondContact NE2-OH 3.42Å; Q145-Y299 PolarHBondContact OE1-OH 2.88Å; V270-Y299 HydrophobicContact CG1-CD1 3.56Å; V270-Y299 HydrophobicContact CG1-CD2 4.47Å; V270-Y299 HydrophobicContact CG1-CE1 4.26Å; V270-Y299 HydrophobicContact CG1-CG 3.69Å; V270-Y299 HydrophobicContact CG2-CG 4.42Å; L282-Y299 WeakPolarHBondContact CA-O 3.4Å; Y283-Y299 PolarHBondContact N-O 3.49Å; Y283-Y299 PolarHBondContact O-N 2.99Å; V285-Y299 HydrophobicContact CG2-CD2 4.46Å; V285-Y299 HydrophobicContact CG2-CE2 3.89Å; L288-Y299 HydrophobicContact CD2-CE2 4.45Å; L288-Y299 WeakPolarHBondContact CD2-OH 3.41Å; T297-Y299 HydrophobicContact CG2-CD1 4.26Å; T297-Y299 HydrophobicContact CG2-CE1 3.51Å; T297-Y299 HydrophobicContact CG2-CE2 4.31Å; Y299-N301 PolarHBondContact O-N 3.37Å; Y299-M448 HydrophobicContact CD2-CB 4.43Å; Y299-M448 HydrophobicContact CE2-CB 4.13Å; Y299-M448 WeakPolarHBondContact CE2-O 3.36Å; Y299-M448 VanDerWaalsContact CZ-O 3.23Å; Y299-M448 PolarHBondContact OH-O 3.1Å
300N98.8Very high98.4Very high0 Ų035 Ų350%020%0.196CC..EExtended strand (participates in β ladder)trans-87.5100.7172-172.8-22.4000108.8C268 L269 V270 Q302 V431 V434 M435C268-N300 WeakPolarHBondContact O-CB 3.5Å; C268-N300 PolarHBondContact O-N 3.32Å; L269-N300 WeakPolarHBondContact CA-O 3.36Å; L269-N300 HydrophobicContact CD2-CB 3.87Å; V270-N300 PolarHBondContact N-O 2.98Å; N300-Q302 PolarHBondContact O-N 3.47Å; N300-Q302 WeakPolarHBondContact OD1-CG 3.42Å; N300-Q302 PolarHBondContact OD1-NE2 3.3Å; N300-V431 PolarHBondContact ND2-O 2.93Å; N300-V434 WeakPolarHBondContact OD1-CG1 3.32Å; N300-M435 HydrophobicContact CB-SD 3.91Å
301N98.9Very high98.4Very high0 Ų035 Ų350%020%0.196CC..EExtended strand (participates in β ladder)trans-78.7123.2-174.2-168.723.2000111.3V270 D272 N277 Y279 G280 K281 Y283 Y299V270-N301 HydrophobicContact CG2-CB 3.95Å; V270-N301 WeakPolarHBondContact O-CA 3.39Å; V270-N301 PolarHBondContact O-OD1 3.45Å; D272-N301 PolarHBondContact N-OD1 3.21Å; D272-N301 PolarHBondContact O-ND2 3.21Å; D272-N301 PolarHBondContact O-OD1 3.21Å; N277-N301 PolarHBondContact O-ND2 2.78Å; Y279-N301 CarbonylContact C-O 3.47Å; Y279-N301 WeakPolarHBondContact CA-O 3.33Å; G280-N301 PolarHBondContact N-O 3.1Å; K281-N301 PolarHBondContact O-N 2.85Å; K281-N301 VanDerWaalsContact O-N 3.07Å; Y283-N301 HydrophobicContact CD2-CB 3.8Å; Y283-N301 HydrophobicContact CE2-CB 3.51Å; Y299-N301 PolarHBondContact O-N 3.37Å
302Q98.9Very high98.4Very high16 Ų1634.1 Ų34.18%0.07519%0.192CC..  trans-138.8157.2-172.9-65.9-63.9-15.800112.1L269 V270 N271 Y279 N300 L306 L307 V431L269-Q302 HydrophobicContact CD2-CG 4.17Å; V270-Q302 PolarHBondContact O-N 3.3Å; N271-Q302 PolarHBondContact ND2-O 2.85Å; Y279-Q302 WeakPolarHBondContact CE1-O 3.46Å; N300-Q302 PolarHBondContact O-N 3.47Å; N300-Q302 WeakPolarHBondContact OD1-CG 3.42Å; N300-Q302 PolarHBondContact OD1-NE2 3.3Å; Q302-L306 HydrophobicContact CB-CB 4.42Å; Q302-L306 HydrophobicContact CB-CD2 3.58Å; Q302-L306 HydrophobicContact CG-CD2 3.49Å; Q302-L306 VanDerWaalsContact CG-CD2 3.49Å; Q302-L307 HydrophobicContact CB-CD1 3.7Å; Q302-V431 HydrophobicContact CG-CG1 4.39Å
303P98.6Very high98.4Very high54 Ų5434.9 Ų34.935%0.35119%0.194SC..  trans-59.8141.4172.2-18.630.6000110.8Y279 Q305 L306 L307Y279-P303 HydrophobicContact CD2-CB 4.24Å; Y279-P303 HydrophobicContact CD2-CG 3.66Å; Y279-P303 HydrophobicContact CE2-CB 4.13Å; Y279-P303 HydrophobicContact CE2-CG 4.07Å; Y279-P303 HydrophobicContact CG-CG 4.04Å; P303-Q305 PolarHBondContact O-N 3.16Å; P303-L306 WeakPolarHBondContact O-CB 3.27Å; P303-L306 PolarHBondContact O-N 3.34Å; P303-L307 WeakPolarHBondContact O-CD1 3.44Å
304I98.6Very high98.5Very high35 Ų3530.9 Ų30.918%0.17915%0.152CC..Hα-helixtrans-55.4-29.8-175.8-164.755.9000113.8N271 L306 L307 K308 F413N271-I304 HydrophobicContact CB-CB 4.37Å; N271-I304 HydrophobicContact CB-CD1 3.78Å; N271-I304 PolarHBondContact ND2-N 2.87Å; I304-L306 VanDerWaalsContact C-N 3.34Å; I304-L306 PolarHBondContact O-N 3.09Å; I304-L307 HydrophobicContact CD1-CB 4.48Å; I304-L307 HydrophobicContact CD1-CD2 4.27Å; I304-L307 PolarHBondContact O-N 3.26Å; I304-K308 WeakPolarHBondContact O-CG 3.2Å; I304-K308 PolarHBondContact O-N 3.28Å; I304-K308 VanDerWaalsContact O-N 3.1Å; I304-F413 HydrophobicContact CD1-CD1 3.92Å; I304-F413 HydrophobicContact CD1-CE1 3.8Å; I304-F413 HydrophobicContact CG1-CD1 4.34Å
305Q98.3Very high98.5Very high69 Ų6929.7 Ų29.732%0.32214%0.14SC..Hα-helixtrans-64.9-36.7177.2-168.759.446.100112.4P303 L307 K308 N309P303-Q305 PolarHBondContact O-N 3.16Å; Q305-L307 VanDerWaalsContact C-N 3.35Å; Q305-K308 PolarHBondContact O-N 3.2Å; Q305-N309 PolarHBondContact NE2-OD1 3.04Å; Q305-N309 WeakPolarHBondContact O-CB 3.3Å; Q305-N309 PolarHBondContact O-N 3.23Å; Q305-N309 PolarHBondContact O-OD1 2.86Å
306L98.6Very high98.6Very high41 Ų4129.1 Ų29.122%0.21514%0.14CC..Hα-helixtrans-64.4-42.6176.3-173.487.5000110.6L269 Q302 P303 I304 K308 N309 A310 P428 V431L269-L306 HydrophobicContact CD1-CD2 4.14Å; Q302-L306 HydrophobicContact CB-CB 4.42Å; Q302-L306 HydrophobicContact CB-CD2 3.58Å; Q302-L306 HydrophobicContact CG-CD2 3.49Å; Q302-L306 VanDerWaalsContact CG-CD2 3.49Å; P303-L306 WeakPolarHBondContact O-CB 3.27Å; P303-L306 PolarHBondContact O-N 3.34Å; I304-L306 VanDerWaalsContact C-N 3.34Å; I304-L306 PolarHBondContact O-N 3.09Å; L306-K308 VanDerWaalsContact C-N 3.33Å; L306-K308 PolarHBondContact O-N 3.17Å; L306-N309 PolarHBondContact O-N 3.36Å; L306-A310 WeakPolarHBondContact O-CB 3.5Å; L306-A310 PolarHBondContact O-N 3.19Å; L306-P428 HydrophobicContact CD1-CG 4.48Å; L306-V431 HydrophobicContact CD1-CG2 4.29Å; L306-V431 HydrophobicContact CD2-CG1 4.09Å; L306-V431 HydrophobicContact CD2-CG2 3.65Å
307L98.8Very high98.6Very high0 Ų028.2 Ų28.20%014%0.142CC..Hα-helixtrans-60-44.9177.3-78.470.7000111L269 N271 Q302 P303 I304 Q305 A311 F413 V420L269-L307 HydrophobicContact CB-CD1 4.19Å; L269-L307 HydrophobicContact CB-CG 3.95Å; L269-L307 HydrophobicContact CD1-CG 4.46Å; N271-L307 HydrophobicContact CB-CD1 4.39Å; N271-L307 HydrophobicContact CB-CD2 3.9Å; Q302-L307 HydrophobicContact CB-CD1 3.7Å; P303-L307 WeakPolarHBondContact O-CD1 3.44Å; I304-L307 HydrophobicContact CD1-CB 4.48Å; I304-L307 HydrophobicContact CD1-CD2 4.27Å; I304-L307 PolarHBondContact O-N 3.26Å; Q305-L307 VanDerWaalsContact C-N 3.35Å; L307-A311 VanDerWaalsContact O-CB 3.26Å; L307-A311 WeakPolarHBondContact O-CB 3.42Å; L307-A311 PolarHBondContact O-N 2.95Å; L307-F413 HydrophobicContact CB-CE1 4.43Å; L307-V420 HydrophobicContact CB-CG1 4.45Å; L307-V420 HydrophobicContact CB-CG2 3.76Å; L307-V420 HydrophobicContact CD2-CG1 4.49Å; L307-V420 HydrophobicContact CD2-CG2 4.02Å; L307-V420 HydrophobicContact CG-CG2 3.68Å
308K98.8Very high98.6Very high4 Ų429.6 Ų29.62%0.01716%0.157CC..Hα-helixtrans-60.8-48.6176.1-69.7175.2173.8-170.60111.5I304 Q305 L306 A311 A312 Y387 W390 D410 F413 S414I304-K308 WeakPolarHBondContact O-CG 3.2Å; I304-K308 PolarHBondContact O-N 3.28Å; I304-K308 VanDerWaalsContact O-N 3.1Å; Q305-K308 PolarHBondContact O-N 3.2Å; L306-K308 VanDerWaalsContact C-N 3.33Å; L306-K308 PolarHBondContact O-N 3.17Å; K308-A311 PolarHBondContact O-N 2.62Å; K308-A312 WeakPolarHBondContact O-CB 3.33Å; K308-A312 PolarHBondContact O-N 2.76Å; K308-Y387 HydrophobicContact CB-CD2 3.97Å; K308-Y387 HydrophobicContact CB-CE2 3.76Å; K308-Y387 HydrophobicContact CD-CD2 4.48Å; K308-W390 HydrophobicContact CB-CH2 4.15Å; K308-W390 HydrophobicContact CB-CZ2 3.97Å; K308-W390 HydrophobicContact CG-CZ2 4.01Å; K308-W390 WeakPolarHBondContact O-CH2 3.4Å; K308-D410 WeakPolarHBondContact CD-OD1 3.44Å; K308-D410 WeakPolarHBondContact CE-OD1 3.43Å; K308-D410 PolarHBondContact NZ-O 2.77Å; K308-D410 IonicContact NZ-OD1 2.71Å; K308-D410 PolarHBondContact NZ-OD1 3.1Å; K308-D410 IonicContact NZ-OD2 3.38Å; K308-D410 PolarHBondContact NZ-OD2 3.46Å; K308-F413 HydrophobicContact CD-CD1 4.35Å; K308-F413 HydrophobicContact CG-CD1 3.71Å; K308-F413 HydrophobicContact CG-CD2 4.42Å; K308-F413 HydrophobicContact CG-CE1 3.65Å; K308-F413 HydrophobicContact CG-CE2 4.35Å; K308-F413 HydrophobicContact CG-CG 4.15Å; K308-F413 HydrophobicContact CG-CZ 3.98Å; K308-S414 PolarHBondContact NZ-OG 2.81Å
309N98.6Very high98.6Very high47 Ų4729.4 Ų29.425%0.25116%0.155SC..Hα-helixtrans-59.7-50.9-179.6-68.20.1000111.2Q305 L306 A311 A312 D313 Y387Q305-N309 PolarHBondContact NE2-OD1 3.04Å; Q305-N309 WeakPolarHBondContact O-CB 3.3Å; Q305-N309 PolarHBondContact O-N 3.23Å; Q305-N309 PolarHBondContact O-OD1 2.86Å; L306-N309 PolarHBondContact O-N 3.36Å; N309-A311 VanDerWaalsContact C-N 3.32Å; N309-A311 PolarHBondContact O-N 3.48Å; N309-A312 PolarHBondContact O-N 3.39Å; N309-D313 WeakPolarHBondContact O-CB 3.09Å; N309-D313 VanDerWaalsContact O-CG 3.27Å; N309-D313 PolarHBondContact O-N 3.33Å; N309-Y387 WeakPolarHBondContact CA-OH 3.3Å; N309-Y387 PolarHBondContact OD1-OH 2.89Å
310A98.7Very high98.6Very high3 Ų329.4 Ų29.43%0.02516%0.156CC..Hα-helixtrans-63-38-179.900000112.5L269 L306 S314 V422 L427L269-A310 HydrophobicContact CD1-CB 4.44Å; L306-A310 WeakPolarHBondContact O-CB 3.5Å; L306-A310 PolarHBondContact O-N 3.19Å; A310-S314 WeakPolarHBondContact O-CB 3.35Å; A310-S314 PolarHBondContact O-N 2.79Å; A310-V422 HydrophobicContact CB-CG1 4.33Å; A310-V422 HydrophobicContact CB-CG2 4.07Å; A310-L427 HydrophobicContact CB-CD2 3.78Å
311A98.8Very high98.6Very high0 Ų029.4 Ų29.40%016%0.156CC..Hα-helixtrans-66.2-43.2175.600000112.2L307 K308 N309 S314 I315 V321 L375 W390L307-A311 VanDerWaalsContact O-CB 3.26Å; L307-A311 WeakPolarHBondContact O-CB 3.42Å; L307-A311 PolarHBondContact O-N 2.95Å; K308-A311 PolarHBondContact O-N 2.62Å; N309-A311 VanDerWaalsContact C-N 3.32Å; N309-A311 PolarHBondContact O-N 3.48Å; A311-S314 PolarHBondContact O-N 2.85Å; A311-I315 WeakPolarHBondContact O-CG1 3.38Å; A311-I315 PolarHBondContact O-N 3.4Å; A311-V321 HydrophobicContact CB-CG1 4.09Å; A311-V321 HydrophobicContact CB-CG2 4.2Å; A311-L375 HydrophobicContact CB-CD1 3.95Å; A311-W390 HydrophobicContact CB-CZ3 4.18Å
312A98.7Very high98.6Very high0 Ų029.4 Ų29.40%016%0.156CC..Hα-helixtrans-65.1-42.7177.100000112.1K308 N309 S314 I315 K316 V378 Y387 W390K308-A312 WeakPolarHBondContact O-CB 3.33Å; K308-A312 PolarHBondContact O-N 2.76Å; N309-A312 PolarHBondContact O-N 3.39Å; A312-S314 VanDerWaalsContact C-N 3.31Å; A312-S314 PolarHBondContact O-N 3.24Å; A312-I315 PolarHBondContact O-N 2.84Å; A312-K316 WeakPolarHBondContact O-CB 3.39Å; A312-K316 VanDerWaalsContact O-CG 3.29Å; A312-K316 WeakPolarHBondContact O-CG 3.29Å; A312-K316 PolarHBondContact O-N 3.24Å; A312-V378 HydrophobicContact CB-CG1 4.23Å; A312-Y387 HydrophobicContact CB-CD1 4.28Å; A312-Y387 HydrophobicContact CB-CE1 3.38Å; A312-Y387 HydrophobicContact CB-CE2 4.29Å; A312-Y387 VanDerWaalsContact CB-OH 3.29Å; A312-Y387 WeakPolarHBondContact CB-OH 3.47Å; A312-W390 HydrophobicContact CB-CH2 4.01Å; A312-W390 HydrophobicContact CB-CZ3 4.17Å
313D98.5Very high98.6Very high72 Ų7228.6 Ų28.639%0.38515%0.152SC..Hα-helixtrans-60.9-42176.2-69.8-15.9000110.9N309 I315 K316 E317 F426N309-D313 WeakPolarHBondContact O-CB 3.09Å; N309-D313 VanDerWaalsContact O-CG 3.27Å; N309-D313 PolarHBondContact O-N 3.33Å; D313-I315 PolarHBondContact O-N 3.02Å; D313-K316 PolarHBondContact O-N 3Å; D313-E317 PolarHBondContact O-N 3.19Å; D313-F426 HydrophobicContact CB-CD1 3.94Å
314S98.8Very high98.6Very high0 Ų026 Ų260%014%0.135CC..Hα-helixtrans-60.1-46.7174.2-173.30000112.6A310 A311 A312 K316 E317 G318 E319A310-S314 WeakPolarHBondContact O-CB 3.35Å; A310-S314 PolarHBondContact O-N 2.79Å; A311-S314 PolarHBondContact O-N 2.85Å; A312-S314 VanDerWaalsContact C-N 3.31Å; A312-S314 PolarHBondContact O-N 3.24Å; S314-K316 VanDerWaalsContact C-N 3.34Å; S314-K316 PolarHBondContact O-N 3.46Å; S314-E317 CarbonylContact O-C 3.56Å; S314-E317 PolarHBondContact O-N 2.69Å; S314-G318 PolarHBondContact O-N 2.98Å; S314-G318 VanDerWaalsContact O-N 3.13Å; S314-E319 CarbonylContact C-O 3.59Å; S314-E319 VanDerWaalsContact C-O 3.24Å; S314-E319 PolarHBondContact O-N 2.68Å; S314-E319 VanDerWaalsContact O-O 3.12Å; S314-E319 PolarHBondContact OG-O 2.89Å
315I98.8Very high98.6Very high1 Ų124.4 Ų24.41%0.00513%0.127CC..Hα-helixtrans-62.8-42.7178.5-69.5165.1000110.7I56 A311 A312 D313 E317 G318 E319 V321 L375 V378 W390I56-I315 HydrophobicContact CG2-CG2 4.37Å; A311-I315 WeakPolarHBondContact O-CG1 3.38Å; A311-I315 PolarHBondContact O-N 3.4Å; A312-I315 PolarHBondContact O-N 2.84Å; D313-I315 PolarHBondContact O-N 3.02Å; I315-E317 VanDerWaalsContact C-N 3.28Å; I315-E317 PolarHBondContact O-N 3.16Å; I315-G318 WeakPolarHBondContact O-CA 3.04Å; I315-G318 PolarHBondContact O-N 3.23Å; I315-E319 PolarHBondContact N-O 3.23Å; I315-V321 HydrophobicContact CG1-CG2 4.25Å; I315-L375 HydrophobicContact CD1-CB 3.82Å; I315-V378 HydrophobicContact CB-CG1 4.5Å; I315-V378 HydrophobicContact CD1-CB 4.3Å; I315-V378 HydrophobicContact CD1-CG1 4.48Å; I315-V378 HydrophobicContact CG2-CG1 4.17Å; I315-W390 HydrophobicContact CD1-CE3 4.24Å; I315-W390 HydrophobicContact CD1-CZ3 4.23Å
316K98.3Very high98.6Very high83 Ų8321.4 Ų21.436%0.36111%0.113SC..Hα-helixtrans-64.9-32.4179.3-74.9172177.8179.30112.1H54 A312 D313 S314 G318 D380H54-K316 HydrophobicContact CB-CG 4.17Å; A312-K316 WeakPolarHBondContact O-CB 3.39Å; A312-K316 VanDerWaalsContact O-CG 3.29Å; A312-K316 WeakPolarHBondContact O-CG 3.29Å; A312-K316 PolarHBondContact O-N 3.24Å; D313-K316 PolarHBondContact O-N 3Å; S314-K316 VanDerWaalsContact C-N 3.34Å; S314-K316 PolarHBondContact O-N 3.46Å; K316-G318 VanDerWaalsContact C-N 3.26Å; K316-G318 PolarHBondContact O-N 2.74Å; K316-D380 VanDerWaalsContact NZ-CG 3.26Å; K316-D380 IonicContact NZ-OD1 3.02Å; K316-D380 PolarHBondContact NZ-OD1 3.14Å; K316-D380 IonicContact NZ-OD2 2.85Å; K316-D380 PolarHBondContact NZ-OD2 2.95Å
317E98Very high98.6Very high129 Ų12920 Ų2060%0.60311%0.106SC*.THydrogen-bonded Turntrans-84.97.1170.6-72.5-60138.500113.9D313 S314 I315 F426D313-E317 PolarHBondContact O-N 3.19Å; S314-E317 CarbonylContact O-C 3.56Å; S314-E317 PolarHBondContact O-N 2.69Å; I315-E317 VanDerWaalsContact C-N 3.28Å; I315-E317 PolarHBondContact O-N 3.16Å; E317-F426 HydrophobicContact CB-CE1 3.77Å; E317-F426 HydrophobicContact CB-CZ 3.73Å; E317-F426 HydrophobicContact CG-CE1 3.68Å; E317-F426 HydrophobicContact CG-CZ 4.16Å
318G97.6Very high98.5Very high31 Ų3122.6 Ų22.632%0.3213%0.132SC..THydrogen-bonded Turntrans82.519170.100000116S314 I315 K316S314-G318 PolarHBondContact O-N 2.98Å; S314-G318 VanDerWaalsContact O-N 3.13Å; I315-G318 WeakPolarHBondContact O-CA 3.04Å; I315-G318 PolarHBondContact O-N 3.23Å; K316-G318 VanDerWaalsContact C-N 3.26Å; K316-G318 PolarHBondContact O-N 2.74Å
319E98.4Very high98.5Very high30 Ų3024.8 Ų24.814%0.1414%0.142CC..  trans-110.8124.4175-174.5172.5119.600111.3Y261 K266 S314 I315Y261-E319 HydrophobicContact CE2-CG 4.15Å; K266-E319 IonicContact NZ-OE1 2.76Å; K266-E319 PolarHBondContact NZ-OE1 3.16Å; K266-E319 IonicContact NZ-OE2 3.21Å; K266-E319 PolarHBondContact NZ-OE2 2.78Å; S314-E319 CarbonylContact C-O 3.59Å; S314-E319 VanDerWaalsContact C-O 3.24Å; S314-E319 PolarHBondContact O-N 2.68Å; S314-E319 VanDerWaalsContact O-O 3.12Å; S314-E319 PolarHBondContact OG-O 2.89Å; I315-E319 PolarHBondContact N-O 3.23Å
320A98.7Very high98.4Very high2 Ų223.3 Ų23.32%0.01713%0.134CC..  trans-69.5151.8176.300000111.4I56 V80 L83 I374 L375I56-A320 HydrophobicContact CD1-CB 4.11Å; V80-A320 HydrophobicContact CG1-CB 4.45Å; V80-A320 WeakPolarHBondContact CG1-O 3.1Å; V80-A320 HydrophobicContact CG2-CB 4.26Å; L83-A320 HydrophobicContact CD1-CB 3.47Å; L83-A320 VanDerWaalsContact CD1-CB 3.47Å; A320-I374 HydrophobicContact CB-CD1 4.09Å; A320-L375 WeakPolarHBondContact CA-O 3.42Å; A320-L375 WeakPolarHBondContact CB-O 3.41Å
321V98.9Very high98.4Very high0 Ų024.3 Ų24.30%014%0.138CC..EExtended strand (participates in β ladder)trans-114.5119.2-171.4179.60000109.7A311 I315 I374 L375 V420 V422A311-V321 HydrophobicContact CB-CG1 4.09Å; A311-V321 HydrophobicContact CB-CG2 4.2Å; I315-V321 HydrophobicContact CG1-CG2 4.25Å; V321-I374 CarbonylContact O-C 3.58Å; V321-I374 WeakPolarHBondContact O-CA 3.16Å; V321-L375 HydrophobicContact CB-CB 4.14Å; V321-L375 HydrophobicContact CB-CD1 4.18Å; V321-L375 HydrophobicContact CB-CG 4.39Å; V321-L375 HydrophobicContact CG1-CD1 4.23Å; V321-L375 PolarHBondContact N-O 3.07Å; V321-L375 VanDerWaalsContact N-O 3.13Å; V321-L375 PolarHBondContact O-N 2.87Å; V321-V420 HydrophobicContact CG1-CB 4.07Å; V321-V422 HydrophobicContact CG1-CG1 3.95Å; V321-V422 HydrophobicContact CG2-CG1 4.27Å
322W98.9Very high98.3Very high0 Ų024.9 Ų24.90%014%0.14CC..EExtended strand (participates in β ladder)trans-69.3136.5168-179.1106.5000108.8W73 S76 V80 W146 A372 E419 V421 L451W73-W322 HydrophobicContact CB-CZ2 4.16Å; W73-W322 PolarHBondContact O-NE1 3.21Å; S76-W322 VanDerWaalsContact CB-CD1 3.43Å; V80-W322 HydrophobicContact CG2-CB 4.25Å; W146-W322 HydrophobicContact CE3-CD2 4.25Å; W146-W322 HydrophobicContact CE3-CG 4.24Å; W146-W322 HydrophobicContact CZ3-CB 4.17Å; W146-W322 HydrophobicContact CZ3-CG 4.15Å; W322-A372 HydrophobicContact CH2-CB 4.27Å; W322-A372 HydrophobicContact CZ2-CB 3.46Å; W322-A372 VanDerWaalsContact CZ2-CB 3.46Å; W322-E419 WeakPolarHBondContact CH2-OE2 3.17Å; W322-E419 HydrophobicContact CZ3-CB 4.3Å; W322-E419 HydrophobicContact CZ3-CG 3.78Å; W322-E419 WeakPolarHBondContact CZ3-OE1 3.35Å; W322-V421 HydrophobicContact CB-CB 4.31Å; W322-V421 HydrophobicContact CD2-CG2 4.34Å; W322-V421 HydrophobicContact CE3-CB 4.13Å; W322-V421 HydrophobicContact CE3-CG2 3.5Å; W322-V421 HydrophobicContact CZ3-CG2 3.96Å; W322-V421 PolarHBondContact O-N 3.39Å; W322-L451 HydrophobicContact CH2-CD1 3.48Å; W322-L451 VanDerWaalsContact CH2-CD1 3.48Å; W322-L451 HydrophobicContact CZ2-CD1 3.57Å
323F98.9Very high98.1Very high0 Ų027.4 Ų27.40%016%0.158CC..EExtended strand (participates in β ladder)trans-146.8154.117779.3-80.6000112.1C325 A372 M373 L375 V392 M408 V417 E419 V420F323-C325 HydrophobicContact CD2-CB 4.14Å; F323-C325 HydrophobicContact CE2-CB 3.91Å; F323-A372 CarbonylContact O-C 3.24Å; F323-A372 WeakPolarHBondContact O-CA 3.05Å; F323-M373 HydrophobicContact CD1-CB 4.27Å; F323-M373 WeakPolarHBondContact CD1-O 3.13Å; F323-M373 HydrophobicContact CE1-CB 3.53Å; F323-M373 HydrophobicContact CE2-CE 4.12Å; F323-M373 HydrophobicContact CZ-CB 3.79Å; F323-M373 HydrophobicContact CZ-CE 3.73Å; F323-M373 PolarHBondContact N-O 2.92Å; F323-M373 PolarHBondContact O-N 3.27Å; F323-L375 HydrophobicContact CD1-CD1 4.36Å; F323-L375 HydrophobicContact CD1-CD2 3.68Å; F323-L375 HydrophobicContact CD1-CG 3.57Å; F323-L375 HydrophobicContact CE1-CD2 3.38Å; F323-L375 HydrophobicContact CE1-CG 3.8Å; F323-L375 HydrophobicContact CG-CD2 4.35Å; F323-L375 HydrophobicContact CG-CG 4.25Å; F323-L375 HydrophobicContact CZ-CD2 3.86Å; F323-V392 HydrophobicContact CE1-CG1 3.82Å; F323-V392 HydrophobicContact CE1-CG2 4.19Å; F323-V392 HydrophobicContact CZ-CG1 3.81Å; F323-V392 HydrophobicContact CZ-CG2 3.91Å; F323-M408 HydrophobicContact CE2-CE 4.43Å; F323-M408 HydrophobicContact CE2-SD 4.19Å; F323-M408 HydrophobicContact CZ-CE 4.35Å; F323-M408 HydrophobicContact CZ-SD 4.32Å; F323-V417 HydrophobicContact CD2-CG1 4.13Å; F323-V417 HydrophobicContact CD2-CG2 3.92Å; F323-V417 HydrophobicContact CE2-CG2 3.99Å; F323-E419 CarbonylContact C-O 2.85Å; F323-E419 WeakPolarHBondContact CA-O 3.45Å; F323-E419 VanDerWaalsContact CB-O 3.23Å; F323-E419 WeakPolarHBondContact CB-O 3.38Å; F323-V420 HydrophobicContact CB-CG1 3.91Å
324G98.7Very high97.8Very high0 Ų030.7 Ų30.70%017%0.168CC..EExtended strand (participates in β ladder)trans-117.1138177.700000112.2M369 Y418 E419G324-M369 WeakPolarHBondContact CA-SD 3.31Å; G324-Y418 PolarHBondContact O-N 2.86Å; G324-E419 PolarHBondContact N-O 3.28Å; G324-E419 PolarHBondContact O-N 2.94Å
325C98.8Very high97.7Very high0 Ų033.7 Ų33.70%018%0.184CC..EExtended strand (participates in β ladder)trans-151.4172.1-172.366.80000113F323 T370 H371 M373 W412 Y416 V417F323-C325 HydrophobicContact CD2-CB 4.14Å; F323-C325 HydrophobicContact CE2-CB 3.91Å; C325-T370 PolarHBondContact O-N 3.33Å; C325-H371 PolarHBondContact N-O 3.32Å; C325-H371 PolarHBondContact O-N 2.77Å; C325-M373 WeakPolarHBondContact SG-CE 3.16Å; C325-W412 HydrophobicContact CB-CH2 3.79Å; C325-W412 HydrophobicContact CB-CZ3 3.91Å; C325-Y416 CarbonylContact C-O 3.12Å; C325-Y416 WeakPolarHBondContact CA-O 3.46Å; C325-Y416 WeakPolarHBondContact CB-O 3.46Å; C325-V417 HydrophobicContact CB-CG2 4.2Å
326D98.7Very high97.7Very high7 Ų733.7 Ų33.74%0.03718%0.184CC..  trans-91.985.1162.3-163.9-16.4000110.8G328 K329 S367 L368 T370 W412 Y416 Y418D326-G328 PolarHBondContact O-N 3.33Å; D326-G328 VanDerWaalsContact O-N 3.14Å; D326-G328 PolarHBondContact OD1-N 3.36Å; D326-K329 HydrophobicContact CB-CG 4.02Å; D326-K329 VanDerWaalsContact CG-CG 3.49Å; D326-K329 PolarHBondContact O-N 3.24Å; D326-K329 IonicContact OD1-NZ 2.69Å; D326-K329 WeakPolarHBondContact OD2-CG 3.34Å; D326-K329 IonicContact OD2-NZ 3.23Å; D326-K329 PolarHBondContact OD2-NZ 2.95Å; D326-S367 PolarHBondContact OD2-OG 3.05Å; D326-S367 VanDerWaalsContact OD2-OG 3.1Å; D326-L368 WeakPolarHBondContact CB-O 3.23Å; D326-T370 WeakPolarHBondContact CA-OG1 3.14Å; D326-T370 PolarHBondContact OD1-OG1 3.19Å; D326-T370 VanDerWaalsContact OD1-OG1 3.11Å; D326-W412 VanDerWaalsContact O-CZ2 3.3Å; D326-W412 WeakPolarHBondContact O-CZ2 3.47Å; D326-Y416 HydrophobicContact CB-CD1 4.28Å; D326-Y416 PolarHBondContact N-O 3.02Å; D326-Y418 HydrophobicContact CB-CE2 4.11Å
327V98.1Very high97.7Very high12 Ų1230 Ų307%0.07317%0.168CC..THydrogen-bonded Turntrans-63.2-23.4-172.2710000113.5K329 F331 T370 H371 M373 W396V327-K329 VanDerWaalsContact C-N 3.3Å; V327-K329 PolarHBondContact O-N 2.97Å; V327-F331 HydrophobicContact CG2-CD1 4.4Å; V327-F331 HydrophobicContact CG2-CE1 4.33Å; V327-F331 WeakPolarHBondContact O-CB 3.02Å; V327-F331 VanDerWaalsContact O-CD1 3.24Å; V327-F331 WeakPolarHBondContact O-CD1 3.38Å; V327-F331 VanDerWaalsContact O-CG 3.23Å; V327-F331 WeakPolarHBondContact O-CG 3.4Å; V327-T370 PolarHBondContact N-OG1 3.39Å; V327-H371 HydrophobicContact CB-CB 3.84Å; V327-H371 HydrophobicContact CG1-CB 3.41Å; V327-H371 VanDerWaalsContact CG1-CB 3.41Å; V327-M373 HydrophobicContact CB-CE 4.23Å; V327-M373 HydrophobicContact CG2-CE 3.69Å; V327-M373 HydrophobicContact CG2-SD 4.22Å; V327-W396 HydrophobicContact CG1-CH2 3.98Å; V327-W396 HydrophobicContact CG1-CZ2 4.25Å; V327-W396 HydrophobicContact CG2-CH2 3.87Å
328G96.9Very high97.7Very high53 Ų5323.9 Ų23.955%0.54614%0.14SC..THydrogen-bonded Turntrans-75.6-16.9-176.400000114D326D326-G328 PolarHBondContact O-N 3.33Å; D326-G328 VanDerWaalsContact O-N 3.14Å; D326-G328 PolarHBondContact OD1-N 3.36Å
329K98Very high97.8Very high51 Ų5123.3 Ų23.322%0.22213%0.129CC..THydrogen-bonded Turntrans-83.8131.8-174.3-62.6-62.1-164.3-63.40110.8D326 V327 F331 D366 W412 Y416D326-K329 HydrophobicContact CB-CG 4.02Å; D326-K329 VanDerWaalsContact CG-CG 3.49Å; D326-K329 PolarHBondContact O-N 3.24Å; D326-K329 IonicContact OD1-NZ 2.69Å; D326-K329 WeakPolarHBondContact OD2-CG 3.34Å; D326-K329 IonicContact OD2-NZ 3.23Å; D326-K329 PolarHBondContact OD2-NZ 2.95Å; V327-K329 VanDerWaalsContact C-N 3.3Å; V327-K329 PolarHBondContact O-N 2.97Å; K329-F331 PolarHBondContact O-N 2.74Å; K329-F331 VanDerWaalsContact O-N 3.12Å; K329-D366 WeakPolarHBondContact CE-O 3.48Å; K329-D366 PolarHBondContact NZ-O 3.31Å; K329-W412 PolarHBondContact O-NE1 3.44Å; K329-Y416 HydrophobicContact CB-CD1 3.64Å; K329-Y416 HydrophobicContact CB-CD2 3.92Å; K329-Y416 HydrophobicContact CB-CE1 3.49Å; K329-Y416 VanDerWaalsContact CB-CE1 3.49Å; K329-Y416 HydrophobicContact CB-CE2 3.75Å; K329-Y416 HydrophobicContact CB-CG 3.87Å; K329-Y416 HydrophobicContact CD-CE1 4.35Å; K329-Y416 HydrophobicContact CG-CD1 3.77Å; K329-Y416 HydrophobicContact CG-CE1 3.55Å; K329-Y416 HydrophobicContact CG-CG 4.47Å
330H97.8Very high97.7Very high16 Ų1622.8 Ų22.87%0.07413%0.127CC..THydrogen-bonded Turntrans45.147.4177.9-61.7-94.3000113.2D339 M340 V342 Y416H330-D339 PolarHBondContact O-N 3.46Å; H330-M340 PolarHBondContact ND1-O 2.99Å; H330-V342 HydrophobicContact CB-CG1 4.49Å; H330-V342 WeakPolarHBondContact O-CG1 3.47Å; H330-Y416 AromaticContact CD2-CE2 3.45Å; H330-Y416 VanDerWaalsContact CD2-CE2 3.45Å; H330-Y416 WeakPolarHBondContact CD2-CE2 3.45Å; H330-Y416 AromaticContact CD2-CZ 3.66Å; H330-Y416 PolarHBondContact CD2-OH 2.94Å; H330-Y416 PolarHBondContact NE2-OH 3.13Å
331F97.8Very high97.7Very high24 Ų2426.3 Ų26.311%0.10515%0.146CC..EExtended strand (participates in β ladder)trans-126127.8-171.7172.4-126.3000111.5V327 K329 S333 I337 N338 F343 W396 L406V327-F331 HydrophobicContact CG2-CD1 4.4Å; V327-F331 HydrophobicContact CG2-CE1 4.33Å; V327-F331 WeakPolarHBondContact O-CB 3.02Å; V327-F331 VanDerWaalsContact O-CD1 3.24Å; V327-F331 WeakPolarHBondContact O-CD1 3.38Å; V327-F331 VanDerWaalsContact O-CG 3.23Å; V327-F331 WeakPolarHBondContact O-CG 3.4Å; K329-F331 PolarHBondContact O-N 2.74Å; K329-F331 VanDerWaalsContact O-N 3.12Å; F331-S333 VanDerWaalsContact CZ-CA 3.41Å; F331-I337 WeakPolarHBondContact CA-O 3.33Å; F331-I337 WeakPolarHBondContact CD2-O 3.27Å; F331-N338 WeakPolarHBondContact CD2-ND2 3.26Å; F331-N338 WeakPolarHBondContact CD2-OD1 3.43Å; F331-F343 WeakPolarHBondContact O-CE2 3.46Å; F331-F343 WeakPolarHBondContact O-CZ 3.49Å; F331-W396 HydrophobicContact CE1-CH2 4.06Å; F331-W396 AromaticContact CE1-CZ3 3.66Å; F331-W396 HydrophobicContact CE1-CZ3 3.66Å; F331-W396 HydrophobicContact CZ-CH2 4.46Å; F331-W396 AromaticContact CZ-CZ3 3.77Å; F331-W396 HydrophobicContact CZ-CZ3 3.77Å; F331-L406 HydrophobicContact CE2-CD1 3.99Å; F331-L406 HydrophobicContact CE2-CD2 4.11Å; F331-L406 HydrophobicContact CZ-CD1 4.29Å; F331-L406 HydrophobicContact CZ-CD2 4.29Å
332H97.3Very high97.7Very high12 Ų1226.3 Ų26.36%0.05615%0.146CC..EExtended strand (participates in β ladder)trans-107.599172.4-168.5-80.7000110.9E37 L40 K334 L335 G336 I337 V342 F343E37-H332 IonicContact OE1-NE2 3.05Å; E37-H332 IonicContact OE2-NE2 3.44Å; L40-H332 HydrophobicContact CD1-CB 4.49Å; H332-K334 PolarHBondContact O-N 3.08Å; H332-L335 WeakPolarHBondContact ND1-CB 3.47Å; H332-L335 VanDerWaalsContact ND1-CG 3.33Å; H332-L335 WeakPolarHBondContact ND1-CG 3.34Å; H332-L335 PolarHBondContact ND1-N 3.43Å; H332-L335 PolarHBondContact O-N 3.49Å; H332-G336 PolarHBondContact O-N 3.25Å; H332-I337 PolarHBondContact N-O 3.32Å; H332-I337 PolarHBondContact O-N 3.21Å; H332-V342 HydrophobicContact CB-CG2 3.91Å; H332-F343 HydrophobicContact CB-CZ 4.17Å
333S93.5Very high97.6Very high53 Ų5326.9 Ų26.937%0.37115%0.148SC..THydrogen-bonded Turntrans-62.8-39.7-167.5640000115.6F331 L335 G336 G401F331-S333 VanDerWaalsContact CZ-CA 3.41Å; S333-L335 VanDerWaalsContact C-N 3.32Å; S333-L335 PolarHBondContact O-N 2.97Å; S333-G336 PolarHBondContact O-N 3.02Å; S333-G401 PolarHBondContact O-N 2.85Å
334K93.9Very high97.5Very high140 Ų14029.2 Ų29.261%0.60916%0.161SC*.THydrogen-bonded Turntrans-66.5-35.5179.4-64.8174.7-172.1149.80112.4E37 H332 G401E37-K334 IonicContact OE1-NZ 3.52Å; E37-K334 PolarHBondContact OE1-NZ 2.83Å; H332-K334 PolarHBondContact O-N 3.08Å; K334-G401 PolarHBondContact O-N 3.34Å
335L96.4Very high97.5Very high64 Ų6430.6 Ų30.634%0.33517%0.167SC..THydrogen-bonded Turntrans-91.5-17.2-179.3-63.7175.1000112L40 V45 H332 S333 I337L40-L335 HydrophobicContact CD2-CD1 4.22Å; V45-L335 HydrophobicContact CG1-CD1 3.83Å; V45-L335 HydrophobicContact CG2-CD1 3.88Å; H332-L335 WeakPolarHBondContact ND1-CB 3.47Å; H332-L335 VanDerWaalsContact ND1-CG 3.33Å; H332-L335 WeakPolarHBondContact ND1-CG 3.34Å; H332-L335 PolarHBondContact ND1-N 3.43Å; H332-L335 PolarHBondContact O-N 3.49Å; S333-L335 VanDerWaalsContact C-N 3.32Å; S333-L335 PolarHBondContact O-N 2.97Å; L335-I337 HydrophobicContact CB-CD1 3.69Å; L335-I337 HydrophobicContact CB-CG1 3.76Å; L335-I337 HydrophobicContact CD1-CD1 4.05Å
336G97.5Very high97.3Very high0 Ų035.6 Ų35.60%019%0.191CC..THydrogen-bonded Turntrans69.642-179.300000112.2H332 S333 L406 I407H332-G336 PolarHBondContact O-N 3.25Å; S333-G336 PolarHBondContact O-N 3.02Å; G336-L406 CarbonylContact O-C 3.52Å; G336-L406 WeakPolarHBondContact O-CA 3.05Å; G336-L406 WeakPolarHBondContact O-CB 3.49Å; G336-I407 PolarHBondContact O-N 3.46Å
337I98.4Very high97.2Very high6 Ų639.8 Ų39.83%0.03121%0.213CC..EExtended strand (participates in β ladder)trans-114116.4-175.1-54.3178.4000109.5V45 T48 F331 H332 L335 D339 V342 I407V45-I337 HydrophobicContact CG2-CD1 4.43Å; T48-I337 HydrophobicContact CG2-CD1 3.84Å; T48-I337 HydrophobicContact CG2-CG1 3.99Å; F331-I337 WeakPolarHBondContact CA-O 3.33Å; F331-I337 WeakPolarHBondContact CD2-O 3.27Å; H332-I337 PolarHBondContact N-O 3.32Å; H332-I337 PolarHBondContact O-N 3.21Å; L335-I337 HydrophobicContact CB-CD1 3.69Å; L335-I337 HydrophobicContact CB-CG1 3.76Å; L335-I337 HydrophobicContact CD1-CD1 4.05Å; I337-D339 HydrophobicContact CG2-CB 3.77Å; I337-V342 HydrophobicContact CB-CG2 4.23Å; I337-V342 HydrophobicContact CG2-CB 4.4Å; I337-V342 HydrophobicContact CG2-CG2 3.97Å; I337-I407 HydrophobicContact CB-CG2 4.39Å; I337-I407 HydrophobicContact CG1-CG2 4.1Å; I337-I407 HydrophobicContact CG2-CG2 4.4Å
338N98.6Very high97.2Very high1 Ų140.2 Ų40.21%0.00522%0.215CC..EExtended strand (participates in β ladder)trans-104.394.1168.7-69.498.3000108.1F331 L406 I407 M408 T409 W412F331-N338 WeakPolarHBondContact CD2-ND2 3.26Å; F331-N338 WeakPolarHBondContact CD2-OD1 3.43Å; N338-L406 WeakPolarHBondContact OD1-CD1 3.26Å; N338-I407 PolarHBondContact N-O 2.81Å; N338-M408 HydrophobicContact CB-CB 3.99Å; N338-M408 HydrophobicContact CB-CG 4.07Å; N338-M408 WeakPolarHBondContact O-CA 3.47Å; N338-T409 PolarHBondContact O-N 3.46Å; N338-W412 HydrophobicContact CB-CD2 3.74Å; N338-W412 HydrophobicContact CB-CE3 4.27Å; N338-W412 HydrophobicContact CB-CG 3.89Å; N338-W412 HydrophobicContact CB-CZ2 4.28Å; N338-W412 WeakPolarHBondContact ND2-CZ2 3.45Å
339D98.6Very high97.2Very high18 Ų1842.3 Ų42.310%0.09621%0.209CC..  trans-145.2128.5-175.8-176.1-19.9000109.9T44 H330 I337 N341 V342 T409T44-D339 HydrophobicContact CG2-CB 4.36Å; T44-D339 VanDerWaalsContact CG2-OD2 3.23Å; T44-D339 WeakPolarHBondContact CG2-OD2 3.26Å; H330-D339 PolarHBondContact O-N 3.46Å; I337-D339 HydrophobicContact CG2-CB 3.77Å; D339-N341 PolarHBondContact O-N 3.43Å; D339-N341 WeakPolarHBondContact OD1-CB 3.32Å; D339-N341 PolarHBondContact OD1-N 3.43Å; D339-V342 HydrophobicContact CB-CB 4.22Å; D339-V342 WeakPolarHBondContact O-CB 3.44Å; D339-V342 VanDerWaalsContact O-CG1 3.24Å; D339-V342 WeakPolarHBondContact O-CG1 3.49Å; D339-V342 PolarHBondContact O-N 3.23Å; D339-T409 HydrophobicContact CB-CG2 3.78Å; D339-T409 VanDerWaalsContact CG-CG2 3.46Å; D339-T409 WeakPolarHBondContact OD2-CG2 3.29Å
340M98.1Very high97.1Very high19 Ų1942 Ų429%0.09422%0.221CC..THydrogen-bonded Turntrans-51.6-26174.8-64.1-52.1-6300113.3H330 K354 D411 E415 Y416H330-M340 PolarHBondContact ND1-O 2.99Å; M340-K354 WeakPolarHBondContact O-CE 3.46Å; M340-K354 PolarHBondContact O-NZ 3.02Å; M340-D411 HydrophobicContact CG-CB 3.92Å; M340-E415 HydrophobicContact CE-CB 4.31Å; M340-E415 HydrophobicContact CE-CG 3.9Å; M340-E415 HydrophobicContact CG-CG 4.47Å; M340-E415 HydrophobicContact SD-CB 3.92Å; M340-E415 HydrophobicContact SD-CG 3.86Å; M340-Y416 HydrophobicContact CE-CE2 3.86Å; M340-Y416 HydrophobicContact SD-CD2 3.95Å; M340-Y416 HydrophobicContact SD-CE2 3.46Å; M340-Y416 WeakPolarHBondContact SD-CE2 3.31Å
341N97.8Very high97Very high77 Ų7745.3 Ų45.341%0.41224%0.242SC..THydrogen-bonded Turntrans-101.43.4-176.9-58.5-45.3000114H41 T44 D339 F343 K354H41-N341 WeakPolarHBondContact CB-O 3.46Å; T44-N341 PolarHBondContact OG1-O 3.49Å; D339-N341 PolarHBondContact O-N 3.43Å; D339-N341 WeakPolarHBondContact OD1-CB 3.32Å; D339-N341 PolarHBondContact OD1-N 3.43Å; N341-F343 PolarHBondContact O-N 2.9Å; N341-K354 PolarHBondContact OD1-NZ 2.97Å
342V97.9Very high96.8Very high0 Ų045.8 Ų45.80%025%0.248CC..SBendtrans-63.7-27.5-178.377.50000112.9L40 H41 H330 H332 I337 D339L40-V342 HydrophobicContact CD1-CG2 3.82Å; H41-V342 PolarHBondContact N-O 3.03Å; H330-V342 HydrophobicContact CB-CG1 4.49Å; H330-V342 WeakPolarHBondContact O-CG1 3.47Å; H332-V342 HydrophobicContact CB-CG2 3.91Å; I337-V342 HydrophobicContact CB-CG2 4.23Å; I337-V342 HydrophobicContact CG2-CB 4.4Å; I337-V342 HydrophobicContact CG2-CG2 3.97Å; D339-V342 HydrophobicContact CB-CB 4.22Å; D339-V342 WeakPolarHBondContact O-CB 3.44Å; D339-V342 VanDerWaalsContact O-CG1 3.24Å; D339-V342 WeakPolarHBondContact O-CG1 3.49Å; D339-V342 PolarHBondContact O-N 3.23Å
343F98.3Very high96.7Very high11 Ų1148.8 Ų48.85%0.04827%0.267CS..BIsolated β-bridgetrans-124127.9-179.3-60.7-55.5000112.7L36 C39 L40 F331 H332 N341 H345L36-F343 HydrophobicContact CB-CD1 4.47Å; L36-F343 HydrophobicContact CB-CE1 3.94Å; L36-F343 HydrophobicContact CB-CZ 4.12Å; L36-F343 HydrophobicContact CD2-CD2 4.24Å; L36-F343 HydrophobicContact CD2-CE2 4.24Å; L36-F343 HydrophobicContact CD2-CG 4.4Å; L36-F343 HydrophobicContact CD2-CZ 4.39Å; L36-F343 WeakPolarHBondContact O-CD1 3.42Å; L36-F343 VanDerWaalsContact O-CE1 3.26Å; L36-F343 WeakPolarHBondContact O-CE1 3.33Å; C39-F343 HydrophobicContact CB-CB 4.04Å; C39-F343 HydrophobicContact CB-CD1 4.1Å; C39-F343 HydrophobicContact CB-CG 4.45Å; C39-F343 CarbonylContact O-C 3.43Å; C39-F343 WeakPolarHBondContact O-CA 3.44Å; L40-F343 HydrophobicContact CD1-CE1 4.28Å; F331-F343 WeakPolarHBondContact O-CE2 3.46Å; F331-F343 WeakPolarHBondContact O-CZ 3.49Å; H332-F343 HydrophobicContact CB-CZ 4.17Å; N341-F343 PolarHBondContact O-N 2.9Å; F343-H345 WeakPolarHBondContact CB-CE1 3.38Å; F343-H345 PolarHBondContact O-N 2.76Å
344N97.1Very high96.8Very high50 Ų5050.2 Ų50.227%0.26727%0.266SS..  trans-99.367-179.8-159.9-16.6000112.6C39 E346 L347 V348C39-N344 PolarHBondContact O-N 3.21Å; N344-E346 VanDerWaalsContact C-N 3.29Å; N344-E346 PolarHBondContact O-N 3.09Å; N344-L347 HydrophobicContact CB-CB 4.17Å; N344-L347 PolarHBondContact O-N 2.65Å; N344-L347 WeakPolarHBondContact OD1-CB 3.41Å; N344-L347 PolarHBondContact OD1-N 2.7Å; N344-V348 PolarHBondContact O-N 3.08Å
345H96.9Very high96.9Very high29 Ų2949.5 Ų49.513%0.13427%0.27CS..Hα-helixtrans-58.8-37.8-179.9-64.289.7000113.2F343 V348 F349 V351 V353F343-H345 WeakPolarHBondContact CB-CE1 3.38Å; F343-H345 PolarHBondContact O-N 2.76Å; H345-V348 PolarHBondContact O-N 2.97Å; H345-F349 HydrophobicContact CB-CD2 4.45Å; H345-F349 WeakPolarHBondContact O-CB 3.43Å; H345-F349 PolarHBondContact O-N 3.49Å; H345-V351 CarbonylContact C-O 3.5Å; H345-V353 HydrophobicContact CB-CG1 4.42Å; H345-V353 HydrophobicContact CB-CG2 4.15Å; H345-V353 WeakPolarHBondContact ND1-CG2 3.24Å
346E96.2Very high97Very high104 Ų10449.8 Ų49.849%0.48627%0.271SS..Hα-helixtrans-66-39.5-179.9-70.8177.2-167.200111.9N344 G350 V351 S352N344-E346 VanDerWaalsContact C-N 3.29Å; N344-E346 PolarHBondContact O-N 3.09Å; E346-G350 WeakPolarHBondContact O-CA 3.43Å; E346-G350 PolarHBondContact O-N 3.25Å; E346-V351 WeakPolarHBondContact CA-O 3.48Å; E346-V351 PolarHBondContact N-O 2.88Å; E346-S352 WeakPolarHBondContact OE1-CB 3.26Å; E346-S352 PolarHBondContact OE1-OG 3.38Å
347L96.5Very high97Very high96 Ų9652.3 Ų52.350%0.50329%0.289SS..Hα-helixtrans-66.5-44.2176.4-17966.5000111.7R22 N344R22-L347 WeakPolarHBondContact CD-O 3.47Å; N344-L347 HydrophobicContact CB-CB 4.17Å; N344-L347 PolarHBondContact O-N 2.65Å; N344-L347 WeakPolarHBondContact OD1-CB 3.41Å; N344-L347 PolarHBondContact OD1-N 2.7Å
348V97.3Very high97.1Very high20 Ų2052.7 Ų52.712%0.12129%0.29CS..Hα-helixtrans-78.3-48.4-173.7177.10000111.8A26 V38 C39 N344 H345A26-V348 HydrophobicContact CB-CG1 4.16Å; A26-V348 WeakPolarHBondContact CB-O 3.33Å; V38-V348 HydrophobicContact CG1-CG1 3.96Å; V38-V348 HydrophobicContact CG1-CG2 4.17Å; C39-V348 HydrophobicContact CB-CG2 4.46Å; N344-V348 PolarHBondContact O-N 3.08Å; H345-V348 PolarHBondContact O-N 2.97Å
349F96.6Very high97.1Very high98 Ų9853.4 Ų53.443%0.4330%0.296SS..Hα-helixtrans-104.9-10.3-172.1-59.6-67.8000114.1P35 C39 H345 V351P35-F349 HydrophobicContact CB-CZ 3.78Å; C39-F349 WeakPolarHBondContact SG-CE2 3.33Å; H345-F349 HydrophobicContact CB-CD2 4.45Å; H345-F349 WeakPolarHBondContact O-CB 3.43Å; H345-F349 PolarHBondContact O-N 3.49Å; F349-V351 HydrophobicContact CB-CG2 3.76Å; F349-V351 PolarHBondContact O-N 3.18Å
350G95.9Very high97.1Very high45 Ų4556.4 Ų56.446%0.46431%0.31SS..SBendtrans7015.2-172.800000113.7E346E346-G350 WeakPolarHBondContact O-CA 3.43Å; E346-G350 PolarHBondContact O-N 3.25Å
351V95.9Very high97.1Very high85 Ų8555.9 Ų55.952%0.51531%0.307SS..  trans-131143.4179.5-59.20000111.1H345 E346 F349H345-V351 CarbonylContact C-O 3.5Å; E346-V351 WeakPolarHBondContact CA-O 3.48Å; E346-V351 PolarHBondContact N-O 2.88Å; F349-V351 HydrophobicContact CB-CG2 3.76Å; F349-V351 PolarHBondContact O-N 3.18Å
352S94.8Very high97.1Very high33 Ų3352.5 Ų52.523%0.23129%0.288CS..  trans-91141.9173.6-162.20000110.9E346 K354E346-S352 WeakPolarHBondContact OE1-CB 3.26Å; E346-S352 PolarHBondContact OE1-OG 3.38Å; S352-K354 PolarHBondContact OG-N 3.47Å
353V94.4Very high97.1Very high75 Ų7556.4 Ų56.446%0.45531%0.308SS..SBendtrans-10911.2171.4-60.10000111.9H345H345-V353 HydrophobicContact CB-CG1 4.42Å; H345-V353 HydrophobicContact CB-CG2 4.15Å; H345-V353 WeakPolarHBondContact ND1-CG2 3.24Å
354K95.4Very high97.1Very high83 Ų8364.7 Ų64.736%0.36134%0.341SS..  trans-106.911.4-175.4-62.9179.7177.3-179.30113.6M340 N341 S352M340-K354 WeakPolarHBondContact O-CE 3.46Å; M340-K354 PolarHBondContact O-NZ 3.02Å; N341-K354 PolarHBondContact OD1-NZ 2.97Å; S352-K354 PolarHBondContact OG-N 3.47Å
355N96.6Very high97.2Very high126 Ų12665.2 Ų65.267%0.67436%0.357SS*.  trans-76.7-27.4-171.6-64.9-33000113.7
356L98.1Very high97.2Very high69 Ų6967.5 Ų67.536%0.36137%0.371SS..SBendtrans-81.9129.8178.5-61.5179.5000109.5E360 R361 D366L356-E360 HydrophobicContact CB-CB 4.24Å; L356-E360 HydrophobicContact CD2-CB 4.17Å; L356-R361 HydrophobicContact CB-CG 3.51Å; L356-R361 HydrophobicContact CD1-CG 4.12Å; L356-R361 HydrophobicContact CG-CG 4.48Å; L356-R361 PolarHBondContact O-NH1 3.21Å; L356-D366 HydrophobicContact CD1-CB 4.27Å
357S98.6Very high97.3Very high54 Ų5462.6 Ų62.638%0.37835%0.348SS..  trans-66163.3166.9660000111.6A359 E360 R361S357-A359 PolarHBondContact O-N 3.47Å; S357-E360 WeakPolarHBondContact CB-OE2 3.27Å; S357-E360 PolarHBondContact N-OE2 2.81Å; S357-E360 PolarHBondContact O-N 3Å; S357-E360 VanDerWaalsContact O-N 3.12Å; S357-E360 VanDerWaalsContact OG-CD 3.31Å; S357-E360 WeakPolarHBondContact OG-CG 3.36Å; S357-E360 PolarHBondContact OG-N 3.16Å; S357-E360 PolarHBondContact OG-OE2 3.27Å; S357-R361 WeakPolarHBondContact O-CG 3.37Å; S357-R361 PolarHBondContact O-N 2.9Å
358K98.7Very high97.4Very high14 Ų1460.4 Ų60.46%0.06134%0.336CS..Hα-helixtrans-54.5-38.8175.9-171.2175.5-173.3-179.10113.5N271 P273 L362 S414 E415 V417 Y418N271-K358 PolarHBondContact OD1-NZ 3.02Å; P273-K358 HydrophobicContact CG-CB 3.93Å; P273-K358 HydrophobicContact CG-CD 4.01Å; P273-K358 HydrophobicContact CG-CG 3.79Å; K358-L362 PolarHBondContact O-N 2.97Å; K358-S414 WeakPolarHBondContact CD-O 3.32Å; K358-S414 PolarHBondContact NZ-O 3.07Å; K358-E415 WeakPolarHBondContact CD-O 3.4Å; K358-E415 WeakPolarHBondContact CE-O 3.18Å; K358-E415 WeakPolarHBondContact CG-O 3.41Å; K358-V417 PolarHBondContact NZ-O 3.19Å; K358-Y418 HydrophobicContact CD-CE1 4.36Å; K358-Y418 VanDerWaalsContact CE-CE1 3.45Å; K358-Y418 HydrophobicContact CG-CE1 4.05Å
359A98.7Very high97.4Very high15 Ų1559.5 Ų59.512%0.12433%0.331CS..Hα-helixtrans-66.5-45.5176.700000111.9P273 S357 R361 L362 I363P273-A359 HydrophobicContact CB-CB 4.28Å; P273-A359 HydrophobicContact CG-CB 4.05Å; P273-A359 WeakPolarHBondContact O-CB 3.44Å; S357-A359 PolarHBondContact O-N 3.47Å; A359-R361 PolarHBondContact O-N 2.82Å; A359-L362 PolarHBondContact O-N 3.44Å; A359-I363 WeakPolarHBondContact O-CD1 3.42Å; A359-I363 VanDerWaalsContact O-CG1 3.26Å; A359-I363 WeakPolarHBondContact O-CG1 3.43Å; A359-I363 PolarHBondContact O-N 2.98Å
360E98.8Very high97.5Very high82 Ų8257 Ų5738%0.38332%0.323SS..Hα-helixtrans-64.4-40.4178.1-70162.1139.100111.4L356 S357 L362 I363 Y364L356-E360 HydrophobicContact CB-CB 4.24Å; L356-E360 HydrophobicContact CD2-CB 4.17Å; S357-E360 WeakPolarHBondContact CB-OE2 3.27Å; S357-E360 PolarHBondContact N-OE2 2.81Å; S357-E360 PolarHBondContact O-N 3Å; S357-E360 VanDerWaalsContact O-N 3.12Å; S357-E360 VanDerWaalsContact OG-CD 3.31Å; S357-E360 WeakPolarHBondContact OG-CG 3.36Å; S357-E360 PolarHBondContact OG-N 3.16Å; S357-E360 PolarHBondContact OG-OE2 3.27Å; E360-L362 VanDerWaalsContact C-N 3.31Å; E360-L362 PolarHBondContact O-N 3.18Å; E360-I363 PolarHBondContact O-N 3.37Å; E360-Y364 HydrophobicContact CB-CD2 4.45Å; E360-Y364 WeakPolarHBondContact O-CB 3.46Å; E360-Y364 WeakPolarHBondContact O-CD2 3.26Å; E360-Y364 PolarHBondContact O-N 3.13Å
361R98.8Very high97.6Very high8 Ų855.2 Ų55.23%0.0330%0.303CS..Hα-helixtrans-61.2-38.5176.2-64.8-173.3-56.5-98.57.1112.6L356 S357 A359 G365 D366 S367 E415L356-R361 HydrophobicContact CB-CG 3.51Å; L356-R361 HydrophobicContact CD1-CG 4.12Å; L356-R361 HydrophobicContact CG-CG 4.48Å; L356-R361 PolarHBondContact O-NH1 3.21Å; S357-R361 WeakPolarHBondContact O-CG 3.37Å; S357-R361 PolarHBondContact O-N 2.9Å; A359-R361 PolarHBondContact O-N 2.82Å; R361-G365 PolarHBondContact O-N 3.37Å; R361-D366 HydrophobicContact CB-CB 4.03Å; R361-D366 VanDerWaalsContact CD-OD2 3.27Å; R361-D366 WeakPolarHBondContact CD-OD2 3.23Å; R361-D366 HydrophobicContact CG-CB 4.19Å; R361-D366 WeakPolarHBondContact CG-OD2 3.46Å; R361-D366 PolarHBondContact O-N 3.43Å; R361-S367 PolarHBondContact O-N 3.34Å; R361-S367 VanDerWaalsContact O-N 3.15Å; R361-E415 IonicContact CZ-OE2 2.95Å; R361-E415 VanDerWaalsContact CZ-OE2 3.24Å; R361-E415 IonicContact NH1-OE2 3.79Å; R361-E415 PolarHBondContact NH1-OE2 3.47Å; R361-E415 PolarHBondContact NH2-O 3.23Å; R361-E415 IonicContact NH2-OE2 3.78Å; R361-E415 PolarHBondContact NH2-OE2 2.92Å
362L98.4Very high97.8Very high6 Ų651.2 Ų51.23%0.03128%0.279CS..Hα-helixtrans-67-43.1173.6-76.7166.9000112.4P273 R274 K358 A359 E360 S367 Y418 P447 M448P273-L362 HydrophobicContact CG-CD1 4.36Å; R274-L362 HydrophobicContact CG-CB 4.16Å; R274-L362 HydrophobicContact CG-CD1 4.2Å; K358-L362 PolarHBondContact O-N 2.97Å; A359-L362 PolarHBondContact O-N 3.44Å; E360-L362 VanDerWaalsContact C-N 3.31Å; E360-L362 PolarHBondContact O-N 3.18Å; L362-S367 WeakPolarHBondContact CD2-O 3.14Å; L362-Y418 HydrophobicContact CD1-CD1 4.36Å; L362-Y418 HydrophobicContact CD1-CE1 3.8Å; L362-Y418 HydrophobicContact CD2-CD1 4.3Å; L362-Y418 HydrophobicContact CD2-CE1 3.69Å; L362-Y418 HydrophobicContact CG-CE1 3.84Å; L362-P447 HydrophobicContact CD2-CB 4.01Å; L362-P447 HydrophobicContact CD2-CG 4.16Å; L362-M448 HydrophobicContact CD2-SD 4.31Å
363I98.4Very high97.9Very high81 Ų8149.6 Ų49.642%0.41527%0.268SS..Hα-helixtrans-70.3-40.3-176.7-68.6163.8000111.5R274 A359 E360R274-I363 HydrophobicContact CG-CD1 4.2Å; R274-I363 HydrophobicContact CG-CG1 3.9Å; A359-I363 WeakPolarHBondContact O-CD1 3.42Å; A359-I363 VanDerWaalsContact O-CG1 3.26Å; A359-I363 WeakPolarHBondContact O-CG1 3.43Å; A359-I363 PolarHBondContact O-N 2.98Å; E360-I363 PolarHBondContact O-N 3.37Å
364Y98.3Very high98.1Very high186 Ų18646 Ų4673%0.72925%0.246SC*.THydrogen-bonded Turntrans-96.59.1-174.3-72-90.2000113.9E360E360-Y364 HydrophobicContact CB-CD2 4.45Å; E360-Y364 WeakPolarHBondContact O-CB 3.46Å; E360-Y364 WeakPolarHBondContact O-CD2 3.26Å; E360-Y364 PolarHBondContact O-N 3.13Å
365G97.6Very high98.3Very high60 Ų6042.1 Ų42.162%0.61923%0.229SC*.THydrogen-bonded Turntrans72.825.817200000115R361R361-G365 PolarHBondContact O-N 3.37Å
366D98Very high98.4Very high77 Ų7736.1 Ų36.141%0.41220%0.197SC..SBendtrans-88.2-32.9177.2-179.174.3000112.3K329 L356 R361K329-D366 WeakPolarHBondContact CE-O 3.48Å; K329-D366 PolarHBondContact NZ-O 3.31Å; L356-D366 HydrophobicContact CD1-CB 4.27Å; R361-D366 HydrophobicContact CB-CB 4.03Å; R361-D366 VanDerWaalsContact CD-OD2 3.27Å; R361-D366 WeakPolarHBondContact CD-OD2 3.23Å; R361-D366 HydrophobicContact CG-CB 4.19Å; R361-D366 WeakPolarHBondContact CG-OD2 3.46Å; R361-D366 PolarHBondContact O-N 3.43Å
367S98.4Very high98.5Very high1 Ų132.8 Ų32.81%0.00718%0.18CC..  trans-144.8143.1-176.3-168.40000111.2D326 R361 L362 Y418D326-S367 PolarHBondContact OD2-OG 3.05Å; D326-S367 VanDerWaalsContact OD2-OG 3.1Å; R361-S367 PolarHBondContact O-N 3.34Å; R361-S367 VanDerWaalsContact O-N 3.15Å; L362-S367 WeakPolarHBondContact CD2-O 3.14Å; S367-Y418 WeakPolarHBondContact CB-OH 3.38Å; S367-Y418 PolarHBondContact OG-OH 3.08Å
368L98Very high98.5Very high50 Ų5030.2 Ų30.226%0.26216%0.162SC..  trans-163.616917757.3108.2000108.4D326 T370 P447 S450D326-L368 WeakPolarHBondContact CB-O 3.23Å; L368-T370 HydrophobicContact CD1-CG2 4.16Å; L368-T370 PolarHBondContact O-N 3.49Å; L368-P447 HydrophobicContact CB-CB 3.97Å; L368-S450 WeakPolarHBondContact CD1-OG 3.37Å
369M97.5Very high98.5Very high2 Ų230.2 Ų30.21%0.0116%0.163CC..  trans-69.5121.1179.7177.9166.665.700111.4Q145 G324 Y418 E419 S450 L451Q145-M369 VanDerWaalsContact NE2-CE 3.31Å; Q145-M369 VanDerWaalsContact OE1-CE 3.29Å; G324-M369 WeakPolarHBondContact CA-SD 3.31Å; M369-Y418 HydrophobicContact CB-CD2 4.14Å; M369-E419 WeakPolarHBondContact CE-OE2 3.4Å; M369-E419 HydrophobicContact SD-CB 3.98Å; M369-E419 VanDerWaalsContact SD-OE2 3.33Å; M369-S450 WeakPolarHBondContact CB-O 3.49Å; M369-S450 WeakPolarHBondContact CE-O 3.42Å; M369-S450 CarbonylContact O-C 3.52Å; M369-S450 VanDerWaalsContact O-C 3.27Å; M369-S450 WeakPolarHBondContact O-CB 3.33Å; M369-S450 VanDerWaalsContact O-O 3.08Å; M369-S450 PolarHBondContact O-OG 2.91Å; M369-L451 HydrophobicContact CE-CB 4.11Å; M369-L451 HydrophobicContact CE-CD1 3.86Å; M369-L451 HydrophobicContact CE-CG 4.26Å; M369-L451 HydrophobicContact CG-CB 4.42Å; M369-L451 HydrophobicContact CG-CD1 4.31Å; M369-L451 HydrophobicContact CG-CG 4.09Å; M369-L451 HydrophobicContact SD-CD1 3.87Å; M369-L451 HydrophobicContact SD-CG 4.3Å
370T98.1Very high98.4Very high44 Ų4431.4 Ų31.427%0.2717%0.167SC..  trans-119.7-18.6-175.457.20000113.1C325 D326 V327 L368 A452C325-T370 PolarHBondContact O-N 3.33Å; D326-T370 WeakPolarHBondContact CA-OG1 3.14Å; D326-T370 PolarHBondContact OD1-OG1 3.19Å; D326-T370 VanDerWaalsContact OD1-OG1 3.11Å; V327-T370 PolarHBondContact N-OG1 3.39Å; L368-T370 HydrophobicContact CD1-CG2 4.16Å; L368-T370 PolarHBondContact O-N 3.49Å; T370-A452 WeakPolarHBondContact O-CA 3.39Å; T370-A452 PolarHBondContact O-N 3.29Å
371H98.6Very high98.1Very high9 Ų932.4 Ų32.44%0.04217%0.17CC..EExtended strand (participates in β ladder)trans-154.4145.1-174.8-168.464.6000112.2C72 C325 V327 M373 N394 W396C72-H371 WeakPolarHBondContact CB-CE1 3.5Å; C72-H371 WeakPolarHBondContact CB-ND1 3.31Å; C72-H371 PolarHBondContact SG-ND1 2.91Å; C72-H371 VanDerWaalsContact SG-ND1 3.37Å; C325-H371 PolarHBondContact N-O 3.32Å; C325-H371 PolarHBondContact O-N 2.77Å; V327-H371 HydrophobicContact CB-CB 3.84Å; V327-H371 HydrophobicContact CG1-CB 3.41Å; V327-H371 VanDerWaalsContact CG1-CB 3.41Å; H371-M373 VanDerWaalsContact CD2-CG 3.4Å; H371-M373 WeakPolarHBondContact CD2-CG 3.31Å; H371-N394 PolarHBondContact NE2-OD1 3.22Å; H371-W396 AromaticContact CD2-CZ2 3.83Å; H371-W396 AromaticContact CE1-CE2 3.67Å; H371-W396 AromaticContact CE1-CZ2 3.64Å; H371-W396 AromaticContact CE1-NE1 3.35Å; H371-W396 PolarHBondContact CE1-NE1 3.43Å; H371-W396 VanDerWaalsContact CE1-NE1 3.35Å; H371-W396 AromaticContact NE2-CE2 3.68Å; H371-W396 AromaticContact NE2-CZ2 3.5Å; H371-W396 WeakPolarHBondContact NE2-CZ2 3.29Å; H371-W396 AromaticContact NE2-NE1 3.74Å
372A98.8Very high97.4Very high0 Ų035.1 Ų35.10%020%0.201CC..EExtended strand (participates in β ladder)trans-110.3139.1174.700000111.6C72 W73 S76 W322 F323 L451C72-A372 PolarHBondContact SG-N 2.82Å; C72-A372 VanDerWaalsContact SG-N 3.38Å; W73-A372 HydrophobicContact CB-CB 4.27Å; S76-A372 VanDerWaalsContact OG-C 3.22Å; S76-A372 PolarHBondContact OG-O 2.91Å; W322-A372 HydrophobicContact CH2-CB 4.27Å; W322-A372 HydrophobicContact CZ2-CB 3.46Å; W322-A372 VanDerWaalsContact CZ2-CB 3.46Å; F323-A372 CarbonylContact O-C 3.24Å; F323-A372 WeakPolarHBondContact O-CA 3.05Å; A372-L451 HydrophobicContact CB-CD1 4.11Å; A372-L451 HydrophobicContact CB-CD2 4Å
373M98.8Very high96.1Very high0 Ų039.1 Ų39.10%024%0.243CC..EExtended strand (participates in β ladder)trans-139.8-174.5178.6-65.4-180-73.800109.7S76 F323 C325 V327 H371 V392 N394 L406S76-M373 WeakPolarHBondContact OG-CA 3.19Å; S76-M373 PolarHBondContact OG-N 2.89Å; F323-M373 HydrophobicContact CD1-CB 4.27Å; F323-M373 WeakPolarHBondContact CD1-O 3.13Å; F323-M373 HydrophobicContact CE1-CB 3.53Å; F323-M373 HydrophobicContact CE2-CE 4.12Å; F323-M373 HydrophobicContact CZ-CB 3.79Å; F323-M373 HydrophobicContact CZ-CE 3.73Å; F323-M373 PolarHBondContact N-O 2.92Å; F323-M373 PolarHBondContact O-N 3.27Å; C325-M373 WeakPolarHBondContact SG-CE 3.16Å; V327-M373 HydrophobicContact CB-CE 4.23Å; V327-M373 HydrophobicContact CG2-CE 3.69Å; V327-M373 HydrophobicContact CG2-SD 4.22Å; H371-M373 VanDerWaalsContact CD2-CG 3.4Å; H371-M373 WeakPolarHBondContact CD2-CG 3.31Å; M373-V392 HydrophobicContact CB-CG1 3.53Å; M373-V392 HydrophobicContact CE-CG1 4Å; M373-V392 HydrophobicContact CG-CG1 4.08Å; M373-V392 HydrophobicContact SD-CG1 3.52Å; M373-V392 VanDerWaalsContact SD-CG1 3.52Å; M373-N394 HydrophobicContact SD-CB 4.05Å; M373-N394 VanDerWaalsContact SD-CG 3.59Å; M373-L406 HydrophobicContact CE-CD1 4.19Å; M373-L406 HydrophobicContact SD-CD1 3.56Å; M373-L406 VanDerWaalsContact SD-CD1 3.56Å
374I98.8Very high95Very high0 Ų042.8 Ų42.80%026%0.256CS..EExtended strand (participates in β ladder)trans-123.3143.417269.6162.1000112.3S76 N79 V80 A320 V321 T376 V392 E393S76-I374 WeakPolarHBondContact O-CG2 3.18Å; N79-I374 HydrophobicContact CB-CD1 3.89Å; N79-I374 HydrophobicContact CB-CG1 4.46Å; N79-I374 HydrophobicContact CB-CG2 4.3Å; V80-I374 HydrophobicContact CG2-CB 4.13Å; V80-I374 HydrophobicContact CG2-CG2 3.47Å; V80-I374 VanDerWaalsContact CG2-CG2 3.47Å; A320-I374 HydrophobicContact CB-CD1 4.09Å; V321-I374 CarbonylContact O-C 3.58Å; V321-I374 WeakPolarHBondContact O-CA 3.16Å; I374-T376 HydrophobicContact CD1-CG2 3.82Å; I374-T376 HydrophobicContact CG1-CG2 4.06Å; I374-V392 CarbonylContact O-C 3.48Å; I374-V392 VanDerWaalsContact O-CA 3.26Å; I374-V392 WeakPolarHBondContact O-CA 3.42Å; I374-E393 HydrophobicContact CD1-CB 3.93Å; I374-E393 HydrophobicContact CG1-CB 3.52Å; I374-E393 HydrophobicContact CG1-CG 4.41Å; I374-E393 PolarHBondContact N-O 2.71Å; I374-E393 PolarHBondContact O-N 2.96Å
375L98.9Very high94.4Very high0 Ų042 Ų420%026%0.259CS..EExtended strand (participates in β ladder)trans-89.6129.9170.8-51.3171.1000109.6A311 I315 A320 V321 F323 W390 R391 V392 M408 F413A311-L375 HydrophobicContact CB-CD1 3.95Å; I315-L375 HydrophobicContact CD1-CB 3.82Å; A320-L375 WeakPolarHBondContact CA-O 3.42Å; A320-L375 WeakPolarHBondContact CB-O 3.41Å; V321-L375 HydrophobicContact CB-CB 4.14Å; V321-L375 HydrophobicContact CB-CD1 4.18Å; V321-L375 HydrophobicContact CB-CG 4.39Å; V321-L375 HydrophobicContact CG1-CD1 4.23Å; V321-L375 PolarHBondContact N-O 3.07Å; V321-L375 VanDerWaalsContact N-O 3.13Å; V321-L375 PolarHBondContact O-N 2.87Å; F323-L375 HydrophobicContact CD1-CD1 4.36Å; F323-L375 HydrophobicContact CD1-CD2 3.68Å; F323-L375 HydrophobicContact CD1-CG 3.57Å; F323-L375 HydrophobicContact CE1-CD2 3.38Å; F323-L375 HydrophobicContact CE1-CG 3.8Å; F323-L375 HydrophobicContact CG-CD2 4.35Å; F323-L375 HydrophobicContact CG-CG 4.25Å; F323-L375 HydrophobicContact CZ-CD2 3.86Å; L375-W390 HydrophobicContact CD1-CE3 4.16Å; L375-W390 HydrophobicContact CD1-CZ3 4.48Å; L375-W390 HydrophobicContact CD2-CB 4.26Å; L375-R391 WeakPolarHBondContact CA-O 3.26Å; L375-V392 HydrophobicContact CD2-CG2 3.98Å; L375-M408 HydrophobicContact CD2-CE 3.5Å; L375-F413 HydrophobicContact CD1-CE2 3.88Å
376T98.8Very high94.2Very high0 Ų040 Ų400%024%0.238CC..EExtended strand (participates in β ladder)trans-120.8-15.7-177.665.40000113.9S55 I56 E59 I374 R391 E393 Y405S55-T376 WeakPolarHBondContact CA-O 3.38Å; I56-T376 HydrophobicContact CD1-CG2 3.88Å; I56-T376 WeakPolarHBondContact CG1-O 3.37Å; I56-T376 PolarHBondContact N-O 3.37Å; E59-T376 WeakPolarHBondContact OE1-CB 3.44Å; E59-T376 PolarHBondContact OE1-OG1 3.13Å; I374-T376 HydrophobicContact CD1-CG2 3.82Å; I374-T376 HydrophobicContact CG1-CG2 4.06Å; T376-R391 PolarHBondContact N-O 2.75Å; T376-R391 WeakPolarHBondContact OG1-CD 3.4Å; T376-R391 WeakPolarHBondContact OG1-CG 3.33Å; T376-E393 HydrophobicContact CG2-CB 4.07Å; T376-Y405 HydrophobicContact CG2-CE1 4.43Å
377A98.8Very high94.2Very high0 Ų037.3 Ų37.30%022%0.223CC..EExtended strand (participates in β ladder)trans-155.3158.3177.300000112F52 H54 W390 R391F52-A377 HydrophobicContact CB-CB 3.54Å; F52-A377 HydrophobicContact CD1-CB 4.35Å; F52-A377 HydrophobicContact CD2-CB 4.27Å; F52-A377 HydrophobicContact CG-CB 3.8Å; H54-A377 CarbonylContact O-C 3.42Å; H54-A377 WeakPolarHBondContact O-CA 3.43Å; H54-A377 WeakPolarHBondContact O-CB 3.41Å; A377-W390 CarbonylContact O-C 3.48Å; A377-W390 WeakPolarHBondContact O-CA 3.39Å; A377-R391 HydrophobicContact CB-CB 3.56Å; A377-R391 HydrophobicContact CB-CG 4.44Å; A377-R391 PolarHBondContact O-N 2.84Å
378V98.7Very high94.1Very high0 Ų041.8 Ų41.80%024%0.243CC..EExtended strand (participates in β ladder)trans-142151.6177.8650000110.6Q53 H54 A312 I315 Y387 K389 W390Q53-V378 PolarHBondContact N-O 3.24Å; H54-V378 HydrophobicContact CB-CG1 4.08Å; H54-V378 PolarHBondContact N-O 3.39Å; H54-V378 PolarHBondContact O-N 2.78Å; A312-V378 HydrophobicContact CB-CG1 4.23Å; I315-V378 HydrophobicContact CB-CG1 4.5Å; I315-V378 HydrophobicContact CD1-CB 4.3Å; I315-V378 HydrophobicContact CD1-CG1 4.48Å; I315-V378 HydrophobicContact CG2-CG1 4.17Å; V378-Y387 HydrophobicContact CG2-CD1 3.5Å; V378-Y387 HydrophobicContact CG2-CE1 4.19Å; V378-Y387 HydrophobicContact CG2-CG 3.99Å; V378-K389 WeakPolarHBondContact CA-O 3.45Å; V378-W390 HydrophobicContact CB-CD2 4.47Å; V378-W390 HydrophobicContact CB-CE3 3.8Å; V378-W390 HydrophobicContact CB-CZ3 3.88Å; V378-W390 HydrophobicContact CG2-CD2 3.91Å; V378-W390 HydrophobicContact CG2-CE3 3.57Å; V378-W390 HydrophobicContact CG2-CH2 3.77Å; V378-W390 HydrophobicContact CG2-CZ2 4.1Å; V378-W390 HydrophobicContact CG2-CZ3 3.51Å
379T98.5Very high94.1Very high14 Ų1441.3 Ų41.39%0.08624%0.239CC..EExtended strand (participates in β ladder)trans-119.8124.9170.8-55.40000109.3F52 Q53 Y387 E388 K389F52-T379 WeakPolarHBondContact CA-OG1 3.38Å; Q53-T379 HydrophobicContact CB-CG2 4.13Å; Q53-T379 PolarHBondContact N-OG1 2.96Å; T379-Y387 WeakPolarHBondContact O-CA 3.43Å; T379-E388 HydrophobicContact CG2-CB 4.41Å; T379-E388 PolarHBondContact O-N 3.13Å; T379-K389 PolarHBondContact N-O 2.98Å
380D96.8Very high94.2Very high40 Ų4041.2 Ų41.221%0.21424%0.239CC..EExtended strand (participates in β ladder)trans-73.7154.1177.1-66.4-27.6000110H54 K316 G382 Y387H54-D380 IonicContact CD2-OD2 3.21Å; H54-D380 IonicContact NE2-OD2 3.44Å; H54-D380 PolarHBondContact NE2-OD2 3.28Å; K316-D380 VanDerWaalsContact NZ-CG 3.26Å; K316-D380 IonicContact NZ-OD1 3.02Å; K316-D380 PolarHBondContact NZ-OD1 3.14Å; K316-D380 IonicContact NZ-OD2 2.85Å; K316-D380 PolarHBondContact NZ-OD2 2.95Å; D380-G382 PolarHBondContact O-N 3.41Å; D380-Y387 WeakPolarHBondContact OD1-CD1 3.44Å; D380-Y387 WeakPolarHBondContact OD1-CE1 3.33Å
381K93.4Very high94.2Very high103 Ų10340.7 Ų40.745%0.44823%0.232SC..  trans-76.7117.5174.9-164.9170.4-171.8165.80110.3G383 K384 G386 E388K381-G383 PolarHBondContact O-N 2.97Å; K381-K384 HydrophobicContact CD-CB 4.45Å; K381-K384 HydrophobicContact CG-CB 4.36Å; K381-K384 PolarHBondContact O-N 3.48Å; K381-G386 WeakPolarHBondContact CB-O 3.47Å; K381-G386 PolarHBondContact N-O 2.83Å; K381-E388 HydrophobicContact CB-CG 4.16Å; K381-E388 HydrophobicContact CG-CG 4.24Å
382G83.3Confident94.2Very high65 Ų6540.3 Ų40.367%0.6723%0.23SC*.THydrogen-bonded Turntrans-49.8110.9-173.400000114.1D380 K384 E388D380-G382 PolarHBondContact O-N 3.41Å; G382-K384 VanDerWaalsContact C-N 3.3Å; G382-K384 PolarHBondContact O-N 2.91Å; G382-E388 PolarHBondContact N-OE1 3.25Å
383G71.6Confident94.2Very high90 Ų9040.3 Ų40.393%0.92823%0.23SC*.THydrogen-bonded Turntrans70.514.7176.300000115.9K381K381-G383 PolarHBondContact O-N 2.97Å
384K76.4Confident94.2Very high157 Ų15740.4 Ų40.468%0.68323%0.231SC*.SBendtrans-137.8161.9179.4-66-177.1-178.8178.40111.2K381 G382K381-K384 HydrophobicContact CD-CB 4.45Å; K381-K384 HydrophobicContact CG-CB 4.36Å; K381-K384 PolarHBondContact O-N 3.48Å; G382-K384 VanDerWaalsContact C-N 3.3Å; G382-K384 PolarHBondContact O-N 2.91Å
385E85Confident94.2Very high170 Ų17040.4 Ų40.479%0.79423%0.231SC*.SBendtrans-69139.4168.6-164.5177.8177.600110.4
386G92.6Very high94.2Very high17 Ų1742.4 Ų42.418%0.17524%0.238CC..SBendtrans110.5-175.4179.600000114.3K381K381-G386 WeakPolarHBondContact CB-O 3.47Å; K381-G386 PolarHBondContact N-O 2.83Å
387Y97.8Very high94.1Very high22 Ų2242.6 Ų42.69%0.08624%0.24CC..EExtended strand (participates in β ladder)trans-126.3160.5-171.7-49.9-76.3000110.9K308 N309 A312 V378 T379 D380 W390 D410K308-Y387 HydrophobicContact CB-CD2 3.97Å; K308-Y387 HydrophobicContact CB-CE2 3.76Å; K308-Y387 HydrophobicContact CD-CD2 4.48Å; N309-Y387 WeakPolarHBondContact CA-OH 3.3Å; N309-Y387 PolarHBondContact OD1-OH 2.89Å; A312-Y387 HydrophobicContact CB-CD1 4.28Å; A312-Y387 HydrophobicContact CB-CE1 3.38Å; A312-Y387 HydrophobicContact CB-CE2 4.29Å; A312-Y387 VanDerWaalsContact CB-OH 3.29Å; A312-Y387 WeakPolarHBondContact CB-OH 3.47Å; V378-Y387 HydrophobicContact CG2-CD1 3.5Å; V378-Y387 HydrophobicContact CG2-CE1 4.19Å; V378-Y387 HydrophobicContact CG2-CG 3.99Å; T379-Y387 WeakPolarHBondContact O-CA 3.43Å; D380-Y387 WeakPolarHBondContact OD1-CD1 3.44Å; D380-Y387 WeakPolarHBondContact OD1-CE1 3.33Å; Y387-W390 HydrophobicContact CD1-CH2 4.35Å; Y387-W390 HydrophobicContact CD1-CZ2 4.37Å; Y387-W390 AromaticContact CD2-CH2 3.85Å; Y387-W390 HydrophobicContact CD2-CH2 3.85Å; Y387-W390 AromaticContact CD2-CZ2 3.46Å; Y387-W390 HydrophobicContact CD2-CZ2 3.46Å; Y387-W390 VanDerWaalsContact CD2-CZ2 3.46Å; Y387-W390 HydrophobicContact CE2-CH2 4.1Å; Y387-W390 HydrophobicContact CE2-CZ2 4.14Å; Y387-W390 AromaticContact CG-CH2 3.98Å; Y387-W390 HydrophobicContact CG-CH2 3.98Å; Y387-W390 AromaticContact CG-CZ2 3.6Å; Y387-W390 HydrophobicContact CG-CZ2 3.6Å; Y387-D410 WeakPolarHBondContact O-CB 3.37Å
388E97.4Very high93.9Very high95 Ų9546.8 Ų46.844%0.44426%0.262SS..EExtended strand (participates in β ladder)trans-102.8-47.1176.6-64.9-178.3175.800111.5T379 K381 G382 D410T379-E388 HydrophobicContact CG2-CB 4.41Å; T379-E388 PolarHBondContact O-N 3.13Å; K381-E388 HydrophobicContact CB-CG 4.16Å; K381-E388 HydrophobicContact CG-CG 4.24Å; G382-E388 PolarHBondContact N-OE1 3.25Å; E388-D410 PolarHBondContact O-N 2.87Å
389K98.3Very high93.7Very high39 Ų3954.1 Ų54.117%0.1730%0.302CS..EExtended strand (participates in β ladder)trans-161.2159.1-171.957.8178175.1-1760112.7V49 I51 F52 V378 T379 I407 M408V49-K389 PolarHBondContact O-NZ 2.78Å; I51-K389 WeakPolarHBondContact O-CE 3.47Å; I51-K389 PolarHBondContact O-NZ 3Å; F52-K389 HydrophobicContact CD1-CD 4.32Å; F52-K389 HydrophobicContact CD1-CG 4.14Å; F52-K389 HydrophobicContact CE1-CB 4.41Å; F52-K389 HydrophobicContact CE1-CD 4.05Å; F52-K389 HydrophobicContact CE1-CG 4.04Å; V378-K389 WeakPolarHBondContact CA-O 3.45Å; T379-K389 PolarHBondContact N-O 2.98Å; K389-I407 HydrophobicContact CB-CD1 4.38Å; K389-I407 HydrophobicContact CB-CG1 4.29Å; K389-I407 HydrophobicContact CD-CD1 3.54Å; K389-I407 HydrophobicContact CD-CG1 4.28Å; K389-M408 CarbonylContact C-O 3.5Å; K389-M408 VanDerWaalsContact CA-O 3.26Å; K389-M408 WeakPolarHBondContact CA-O 3.42Å
390W98.9Very high93.4Very high0 Ų059.3 Ų59.30%032%0.32CS..EExtended strand (participates in β ladder)trans-128.9143.1-174.2-5284.4000109.7F52 K308 A311 A312 I315 L375 A377 V378 Y387 M408 D410 F413F52-W390 WeakPolarHBondContact CE1-O 3.4Å; K308-W390 HydrophobicContact CB-CH2 4.15Å; K308-W390 HydrophobicContact CB-CZ2 3.97Å; K308-W390 HydrophobicContact CG-CZ2 4.01Å; K308-W390 WeakPolarHBondContact O-CH2 3.4Å; A311-W390 HydrophobicContact CB-CZ3 4.18Å; A312-W390 HydrophobicContact CB-CH2 4.01Å; A312-W390 HydrophobicContact CB-CZ3 4.17Å; I315-W390 HydrophobicContact CD1-CE3 4.24Å; I315-W390 HydrophobicContact CD1-CZ3 4.23Å; L375-W390 HydrophobicContact CD1-CE3 4.16Å; L375-W390 HydrophobicContact CD1-CZ3 4.48Å; L375-W390 HydrophobicContact CD2-CB 4.26Å; A377-W390 CarbonylContact O-C 3.48Å; A377-W390 WeakPolarHBondContact O-CA 3.39Å; V378-W390 HydrophobicContact CB-CD2 4.47Å; V378-W390 HydrophobicContact CB-CE3 3.8Å; V378-W390 HydrophobicContact CB-CZ3 3.88Å; V378-W390 HydrophobicContact CG2-CD2 3.91Å; V378-W390 HydrophobicContact CG2-CE3 3.57Å; V378-W390 HydrophobicContact CG2-CH2 3.77Å; V378-W390 HydrophobicContact CG2-CZ2 4.1Å; V378-W390 HydrophobicContact CG2-CZ3 3.51Å; Y387-W390 HydrophobicContact CD1-CH2 4.35Å; Y387-W390 HydrophobicContact CD1-CZ2 4.37Å; Y387-W390 AromaticContact CD2-CH2 3.85Å; Y387-W390 HydrophobicContact CD2-CH2 3.85Å; Y387-W390 AromaticContact CD2-CZ2 3.46Å; Y387-W390 HydrophobicContact CD2-CZ2 3.46Å; Y387-W390 VanDerWaalsContact CD2-CZ2 3.46Å; Y387-W390 HydrophobicContact CE2-CH2 4.1Å; Y387-W390 HydrophobicContact CE2-CZ2 4.14Å; Y387-W390 AromaticContact CG-CH2 3.98Å; Y387-W390 HydrophobicContact CG-CH2 3.98Å; Y387-W390 AromaticContact CG-CZ2 3.6Å; Y387-W390 HydrophobicContact CG-CZ2 3.6Å; W390-M408 HydrophobicContact CB-CB 4.28Å; W390-M408 HydrophobicContact CB-CE 3.59Å; W390-M408 HydrophobicContact CG-CE 3.78Å; W390-M408 PolarHBondContact N-O 2.96Å; W390-M408 PolarHBondContact O-N 2.92Å; W390-D410 PolarHBondContact NE1-OD1 3.48Å; W390-F413 AromaticContact CD1-CD2 3.88Å; W390-F413 AromaticContact CD2-CD2 3.86Å; W390-F413 HydrophobicContact CD2-CD2 3.86Å; W390-F413 HydrophobicContact CD2-CE2 4.14Å; W390-F413 AromaticContact CE2-CD2 3.57Å; W390-F413 AromaticContact CE2-CE2 4Å; W390-F413 HydrophobicContact CE3-CE2 4.34Å; W390-F413 HydrophobicContact CG-CD2 4.07Å; W390-F413 HydrophobicContact CH2-CE2 4.33Å; W390-F413 HydrophobicContact CZ2-CD2 4.02Å; W390-F413 HydrophobicContact CZ2-CE2 4.11Å; W390-F413 HydrophobicContact CZ3-CE2 4.43Å; W390-F413 AromaticContact NE1-CD2 3.59Å
391R98.8Very high93.2Very high34 Ų3458.4 Ų58.413%0.12832%0.319CS..EExtended strand (participates in β ladder)trans-97.6133.4172-172.1174.8170.372.9-3.6109.3F52 E59 L375 T376 A377 Y405F52-R391 HydrophobicContact CD1-CB 3.94Å; F52-R391 HydrophobicContact CD2-CB 3.76Å; F52-R391 HydrophobicContact CD2-CG 4.05Å; F52-R391 HydrophobicContact CE1-CB 3.73Å; F52-R391 HydrophobicContact CE2-CB 3.53Å; F52-R391 HydrophobicContact CE2-CG 3.61Å; F52-R391 HydrophobicContact CG-CB 3.97Å; F52-R391 HydrophobicContact CZ-CB 3.51Å; F52-R391 HydrophobicContact CZ-CG 3.93Å; E59-R391 WeakPolarHBondContact OE1-CD 3.47Å; E59-R391 IonicContact OE1-CZ 3.72Å; E59-R391 IonicContact OE1-NE 2.84Å; E59-R391 PolarHBondContact OE1-NE 3.13Å; E59-R391 IonicContact OE1-NH2 3.62Å; E59-R391 IonicContact OE2-CZ 3.74Å; E59-R391 IonicContact OE2-NE 2.76Å; E59-R391 PolarHBondContact OE2-NE 2.78Å; E59-R391 IonicContact OE2-NH2 3.56Å; E59-R391 PolarHBondContact OE2-NH2 2.68Å; L375-R391 WeakPolarHBondContact CA-O 3.26Å; T376-R391 PolarHBondContact N-O 2.75Å; T376-R391 WeakPolarHBondContact OG1-CD 3.4Å; T376-R391 WeakPolarHBondContact OG1-CG 3.33Å; A377-R391 HydrophobicContact CB-CB 3.56Å; A377-R391 HydrophobicContact CB-CG 4.44Å; A377-R391 PolarHBondContact O-N 2.84Å; R391-Y405 HydrophobicContact CG-CD1 4.09Å; R391-Y405 VanDerWaalsContact CZ-CD1 3.43Å; R391-Y405 VanDerWaalsContact CZ-CG 3.4Å
392V98.8Very high93.3Very high0 Ų056.6 Ų56.60%032%0.315CS..EExtended strand (participates in β ladder)trans-121.6125.2-175.7-1800000109.4F323 M373 I374 L375 Y405 L406 M408F323-V392 HydrophobicContact CE1-CG1 3.82Å; F323-V392 HydrophobicContact CE1-CG2 4.19Å; F323-V392 HydrophobicContact CZ-CG1 3.81Å; F323-V392 HydrophobicContact CZ-CG2 3.91Å; M373-V392 HydrophobicContact CB-CG1 3.53Å; M373-V392 HydrophobicContact CE-CG1 4Å; M373-V392 HydrophobicContact CG-CG1 4.08Å; M373-V392 HydrophobicContact SD-CG1 3.52Å; M373-V392 VanDerWaalsContact SD-CG1 3.52Å; I374-V392 CarbonylContact O-C 3.48Å; I374-V392 VanDerWaalsContact O-CA 3.26Å; I374-V392 WeakPolarHBondContact O-CA 3.42Å; L375-V392 HydrophobicContact CD2-CG2 3.98Å; V392-Y405 CarbonylContact O-C 3.5Å; V392-Y405 WeakPolarHBondContact O-CA 3.29Å; V392-Y405 WeakPolarHBondContact O-CB 3.39Å; V392-Y405 WeakPolarHBondContact O-CD1 3.2Å; V392-L406 HydrophobicContact CB-CB 4.02Å; V392-L406 HydrophobicContact CB-CG 4.37Å; V392-L406 HydrophobicContact CG1-CD1 4.24Å; V392-L406 HydrophobicContact CG1-CG 4.42Å; V392-L406 PolarHBondContact N-O 3.26Å; V392-L406 PolarHBondContact O-N 3.39Å; V392-M408 HydrophobicContact CG2-CB 3.95Å; V392-M408 HydrophobicContact CG2-CE 4.17Å; V392-M408 HydrophobicContact CG2-SD 4.39Å
393E98.8Very high93.9Very high0 Ų060.3 Ų60.30%031%0.313CS..EExtended strand (participates in β ladder)trans-87125.5163.8-170.9179.7140.500108.5I63 N79 R82 I374 T376 Y405I63-E393 HydrophobicContact CD1-CG 4.36Å; N79-E393 PolarHBondContact ND2-OE1 2.85Å; R82-E393 IonicContact CZ-OE1 3.74Å; R82-E393 IonicContact NH2-OE1 3.67Å; R82-E393 PolarHBondContact NH2-OE1 3.19Å; I374-E393 HydrophobicContact CD1-CB 3.93Å; I374-E393 HydrophobicContact CG1-CB 3.52Å; I374-E393 HydrophobicContact CG1-CG 4.41Å; I374-E393 PolarHBondContact N-O 2.71Å; I374-E393 PolarHBondContact O-N 2.96Å; T376-E393 HydrophobicContact CG2-CB 4.07Å; E393-Y405 HydrophobicContact CB-CD1 3.89Å; E393-Y405 HydrophobicContact CB-CE1 3.42Å; E393-Y405 VanDerWaalsContact CB-CE1 3.42Å; E393-Y405 HydrophobicContact CG-CD1 4.34Å; E393-Y405 HydrophobicContact CG-CE1 3.66Å; E393-Y405 PolarHBondContact OE2-OH 3.2Å; E393-Y405 VanDerWaalsContact OE2-OH 3.05Å
394N98.3Very high95.1Very high3 Ų356.2 Ų56.22%0.01627%0.27CS..  trans-104.9170176.6-160.6-1.1000110.9H371 M373 W396 G404 L406H371-N394 PolarHBondContact NE2-OD1 3.22Å; M373-N394 HydrophobicContact SD-CB 4.05Å; M373-N394 VanDerWaalsContact SD-CG 3.59Å; N394-W396 WeakPolarHBondContact ND2-CZ3 3.35Å; N394-G404 WeakPolarHBondContact CB-O 3.29Å; N394-G404 PolarHBondContact N-O 3.27Å; N394-G404 VanDerWaalsContact N-O 3.11Å; N394-L406 HydrophobicContact CB-CD1 4.36Å; N394-L406 HydrophobicContact CB-CG 4.31Å
395S98.3Very high96.2Very high0 Ų049.2 Ų49.20%024%0.239CC..SBendtrans-114.738-176.550.90000112.4T64 N65 Q66T64-S395 CarbonylContact O-C 3.52Å; T64-S395 WeakPolarHBondContact O-CA 3.39Å; N65-S395 CarbonylContact C-O 3.57Å; N65-S395 VanDerWaalsContact CA-O 3.27Å; N65-S395 WeakPolarHBondContact CA-O 3.47Å; Q66-S395 PolarHBondContact N-O 3.05Å; Q66-S395 PolarHBondContact OE1-OG 3.38Å
396W98.3Very high96.8Very high42 Ų4241.2 Ų41.216%0.15920%0.202CC..BIsolated β-bridgetrans-114.817.4-179.2-61-22.4000114.1T64 N65 V327 F331 H371 N394T64-W396 PolarHBondContact O-N 2.9Å; N65-W396 VanDerWaalsContact CG-C 3.45Å; N65-W396 PolarHBondContact ND2-O 3.11Å; V327-W396 HydrophobicContact CG1-CH2 3.98Å; V327-W396 HydrophobicContact CG1-CZ2 4.25Å; V327-W396 HydrophobicContact CG2-CH2 3.87Å; F331-W396 HydrophobicContact CE1-CH2 4.06Å; F331-W396 AromaticContact CE1-CZ3 3.66Å; F331-W396 HydrophobicContact CE1-CZ3 3.66Å; F331-W396 HydrophobicContact CZ-CH2 4.46Å; F331-W396 AromaticContact CZ-CZ3 3.77Å; F331-W396 HydrophobicContact CZ-CZ3 3.77Å; H371-W396 AromaticContact CD2-CZ2 3.83Å; H371-W396 AromaticContact CE1-CE2 3.67Å; H371-W396 AromaticContact CE1-CZ2 3.64Å; H371-W396 AromaticContact CE1-NE1 3.35Å; H371-W396 PolarHBondContact CE1-NE1 3.43Å; H371-W396 VanDerWaalsContact CE1-NE1 3.35Å; H371-W396 AromaticContact NE2-CE2 3.68Å; H371-W396 AromaticContact NE2-CZ2 3.5Å; H371-W396 WeakPolarHBondContact NE2-CZ2 3.29Å; H371-W396 AromaticContact NE2-NE1 3.74Å; N394-W396 WeakPolarHBondContact ND2-CZ3 3.35Å
397G97.4Very high97.1Very high4 Ų440.9 Ų40.94%0.04120%0.196CC..  trans81.3175.4-174.500000113.6T64 G404T64-G397 PolarHBondContact O-N 2.83Å; G397-G404 VanDerWaalsContact O-CA 3.26Å; G397-G404 WeakPolarHBondContact O-CA 3.33Å
398D95.8Very high97.2Very high87 Ų8739.8 Ų39.847%0.46519%0.192SC..THydrogen-bonded Turntrans-89.7-5.7-172.962.2-25.4000114.5I63 R400 K403I63-D398 HydrophobicContact CB-CB 4.23Å; I63-D398 HydrophobicContact CG1-CB 4.34Å; I63-D398 HydrophobicContact CG2-CB 4.44Å; D398-R400 VanDerWaalsContact C-N 3.27Å; D398-R400 PolarHBondContact O-N 3Å; D398-K403 WeakPolarHBondContact O-CA 3.5Å
399D94.3Very high97.2Very high155 Ų15536.5 Ų36.583%0.82918%0.178SC*.THydrogen-bonded Turntrans-77-10.2174.2-68.3-37.1000113.7
400R90.4Very high97.2Very high123 Ų12335.6 Ų35.646%0.46418%0.175SC..SBendtrans-109.1150.9-178.3-63.5-168-176.9-175.4-1.4112D398 G404D398-R400 VanDerWaalsContact C-N 3.27Å; D398-R400 PolarHBondContact O-N 3Å; R400-G404 WeakPolarHBondContact O-CA 3.43Å; R400-G404 PolarHBondContact O-N 3.36Å
401G94Very high97.2Very high20 Ų2040.2 Ų40.221%0.20620%0.2CC..THydrogen-bonded Turntrans54.8-138.9-17900000112.8S333 K334 K403S333-G401 PolarHBondContact O-N 2.85Å; K334-G401 PolarHBondContact O-N 3.34Å; G401-K403 PolarHBondContact O-N 3.39Å
402N95.3Very high97.2Very high65 Ų6538.6 Ų38.635%0.34819%0.194SC..BIsolated β-bridgetrans-97.283.5173.6-173.4-1.3000110.1H50 G404 Y405H50-N402 WeakPolarHBondContact CB-ND2 3.27Å; N402-G404 VanDerWaalsContact C-N 3.34Å; N402-G404 PolarHBondContact O-N 2.95Å; N402-Y405 PolarHBondContact N-O 3.04Å; N402-Y405 WeakPolarHBondContact O-CB 3.43Å; N402-Y405 PolarHBondContact O-N 3.5Å; N402-Y405 VanDerWaalsContact O-N 3.08Å
403K96.3Very high97.2Very high144 Ų14438.6 Ų38.663%0.62619%0.194SC*.THydrogen-bonded Turntrans5645.9-178.4-59.7-59.7-174.3-178.60113D398 G401 Y405D398-K403 WeakPolarHBondContact O-CA 3.5Å; G401-K403 PolarHBondContact O-N 3.39Å; K403-Y405 VanDerWaalsContact C-N 3.3Å; K403-Y405 WeakPolarHBondContact O-CD2 3.29Å; K403-Y405 PolarHBondContact O-N 2.92Å
404G96.9Very high97.2Very high3 Ų339.9 Ų39.93%0.03120%0.203CC..THydrogen-bonded Turntrans85.9-6.2-177.700000114.8N394 G397 R400 N402N394-G404 WeakPolarHBondContact CB-O 3.29Å; N394-G404 PolarHBondContact N-O 3.27Å; N394-G404 VanDerWaalsContact N-O 3.11Å; G397-G404 VanDerWaalsContact O-CA 3.26Å; G397-G404 WeakPolarHBondContact O-CA 3.33Å; R400-G404 WeakPolarHBondContact O-CA 3.43Å; R400-G404 PolarHBondContact O-N 3.36Å; N402-G404 VanDerWaalsContact C-N 3.34Å; N402-G404 PolarHBondContact O-N 2.95Å
405Y98.4Very high97.3Very high11 Ų1142.6 Ų42.64%0.04322%0.215CC..EExtended strand (participates in β ladder)trans-100.2150.9178.1-66.3-95.4000112.9E59 I63 T376 R391 V392 E393 N402 K403E59-Y405 WeakPolarHBondContact CB-OH 3.39Å; E59-Y405 VanDerWaalsContact OE1-CE1 3.22Å; E59-Y405 WeakPolarHBondContact OE1-CE1 3.37Å; I63-Y405 HydrophobicContact CD1-CD2 4.17Å; I63-Y405 HydrophobicContact CD1-CE2 3.37Å; T376-Y405 HydrophobicContact CG2-CE1 4.43Å; R391-Y405 HydrophobicContact CG-CD1 4.09Å; R391-Y405 VanDerWaalsContact CZ-CD1 3.43Å; R391-Y405 VanDerWaalsContact CZ-CG 3.4Å; V392-Y405 CarbonylContact O-C 3.5Å; V392-Y405 WeakPolarHBondContact O-CA 3.29Å; V392-Y405 WeakPolarHBondContact O-CB 3.39Å; V392-Y405 WeakPolarHBondContact O-CD1 3.2Å; E393-Y405 HydrophobicContact CB-CD1 3.89Å; E393-Y405 HydrophobicContact CB-CE1 3.42Å; E393-Y405 VanDerWaalsContact CB-CE1 3.42Å; E393-Y405 HydrophobicContact CG-CD1 4.34Å; E393-Y405 HydrophobicContact CG-CE1 3.66Å; E393-Y405 PolarHBondContact OE2-OH 3.2Å; E393-Y405 VanDerWaalsContact OE2-OH 3.05Å; N402-Y405 PolarHBondContact N-O 3.04Å; N402-Y405 WeakPolarHBondContact O-CB 3.43Å; N402-Y405 PolarHBondContact O-N 3.5Å; N402-Y405 VanDerWaalsContact O-N 3.08Å; K403-Y405 VanDerWaalsContact C-N 3.3Å; K403-Y405 WeakPolarHBondContact O-CD2 3.29Å; K403-Y405 PolarHBondContact O-N 2.92Å
406L98.6Very high97.3Very high2 Ų242.8 Ų42.81%0.0122%0.216CC..EExtended strand (participates in β ladder)trans-115159.2173.8-33.2175.2000110.2F331 G336 N338 M373 V392 N394F331-L406 HydrophobicContact CE2-CD1 3.99Å; F331-L406 HydrophobicContact CE2-CD2 4.11Å; F331-L406 HydrophobicContact CZ-CD1 4.29Å; F331-L406 HydrophobicContact CZ-CD2 4.29Å; G336-L406 CarbonylContact O-C 3.52Å; G336-L406 WeakPolarHBondContact O-CA 3.05Å; G336-L406 WeakPolarHBondContact O-CB 3.49Å; N338-L406 WeakPolarHBondContact OD1-CD1 3.26Å; M373-L406 HydrophobicContact CE-CD1 4.19Å; M373-L406 HydrophobicContact SD-CD1 3.56Å; M373-L406 VanDerWaalsContact SD-CD1 3.56Å; V392-L406 HydrophobicContact CB-CB 4.02Å; V392-L406 HydrophobicContact CB-CG 4.37Å; V392-L406 HydrophobicContact CG1-CD1 4.24Å; V392-L406 HydrophobicContact CG1-CG 4.42Å; V392-L406 PolarHBondContact N-O 3.26Å; V392-L406 PolarHBondContact O-N 3.39Å; N394-L406 HydrophobicContact CB-CD1 4.36Å; N394-L406 HydrophobicContact CB-CG 4.31Å
407I98.6Very high97.3Very high9 Ų940.8 Ų40.85%0.04621%0.209CC..EExtended strand (participates in β ladder)trans-109.5131.7163.5-179.4165.7000108.1T48 V49 H50 F52 G336 I337 N338 K389T48-I407 HydrophobicContact CG2-CD1 4.07Å; T48-I407 HydrophobicContact CG2-CG2 3.5Å; T48-I407 VanDerWaalsContact CG2-CG2 3.5Å; V49-I407 WeakPolarHBondContact O-CD1 3.36Å; H50-I407 VanDerWaalsContact CE1-CG2 3.43Å; H50-I407 WeakPolarHBondContact CE1-CG2 3.4Å; F52-I407 HydrophobicContact CE1-CD1 4.4Å; F52-I407 HydrophobicContact CE1-CG1 4.19Å; F52-I407 HydrophobicContact CZ-CB 4.21Å; F52-I407 HydrophobicContact CZ-CD1 4.24Å; F52-I407 HydrophobicContact CZ-CG1 4.05Å; G336-I407 PolarHBondContact O-N 3.46Å; I337-I407 HydrophobicContact CB-CG2 4.39Å; I337-I407 HydrophobicContact CG1-CG2 4.1Å; I337-I407 HydrophobicContact CG2-CG2 4.4Å; N338-I407 PolarHBondContact N-O 2.81Å; K389-I407 HydrophobicContact CB-CD1 4.38Å; K389-I407 HydrophobicContact CB-CG1 4.29Å; K389-I407 HydrophobicContact CD-CD1 3.54Å; K389-I407 HydrophobicContact CD-CG1 4.28Å
408M98.8Very high97.4Very high0 Ų040.7 Ų40.70%021%0.207CC..EExtended strand (participates in β ladder)trans-123.5121.6-179.5177.3178.368.200109F323 N338 L375 K389 W390 V392 W412 F413 V417F323-M408 HydrophobicContact CE2-CE 4.43Å; F323-M408 HydrophobicContact CE2-SD 4.19Å; F323-M408 HydrophobicContact CZ-CE 4.35Å; F323-M408 HydrophobicContact CZ-SD 4.32Å; N338-M408 HydrophobicContact CB-CB 3.99Å; N338-M408 HydrophobicContact CB-CG 4.07Å; N338-M408 WeakPolarHBondContact O-CA 3.47Å; L375-M408 HydrophobicContact CD2-CE 3.5Å; K389-M408 CarbonylContact C-O 3.5Å; K389-M408 VanDerWaalsContact CA-O 3.26Å; K389-M408 WeakPolarHBondContact CA-O 3.42Å; W390-M408 HydrophobicContact CB-CB 4.28Å; W390-M408 HydrophobicContact CB-CE 3.59Å; W390-M408 HydrophobicContact CG-CE 3.78Å; W390-M408 PolarHBondContact N-O 2.96Å; W390-M408 PolarHBondContact O-N 2.92Å; V392-M408 HydrophobicContact CG2-CB 3.95Å; V392-M408 HydrophobicContact CG2-CE 4.17Å; V392-M408 HydrophobicContact CG2-SD 4.39Å; M408-W412 HydrophobicContact CG-CB 4.21Å; M408-W412 HydrophobicContact CG-CD2 4.07Å; M408-W412 HydrophobicContact CG-CE3 3.45Å; M408-W412 VanDerWaalsContact CG-CE3 3.45Å; M408-W412 HydrophobicContact CG-CG 4.4Å; M408-W412 HydrophobicContact CG-CZ3 4.15Å; M408-W412 HydrophobicContact SD-CD2 4.37Å; M408-W412 HydrophobicContact SD-CE3 3.25Å; M408-W412 HydrophobicContact SD-CZ3 3.4Å; M408-W412 WeakPolarHBondContact SD-CZ3 3.42Å; M408-F413 HydrophobicContact CE-CB 4.29Å; M408-F413 HydrophobicContact CE-CD2 3.48Å; M408-F413 VanDerWaalsContact CE-CD2 3.48Å; M408-F413 HydrophobicContact CE-CE2 4.18Å; M408-F413 HydrophobicContact CE-CG 4.22Å; M408-V417 HydrophobicContact CE-CG2 4.32Å; M408-V417 HydrophobicContact SD-CG2 3.93Å
409T98.8Very high97.5Very high26 Ų2636.5 Ų36.516%0.1619%0.185CC..EExtended strand (participates in β ladder)trans-72155.3175.8630000111N338 D339 D411 W412 F413N338-T409 PolarHBondContact O-N 3.46Å; D339-T409 HydrophobicContact CB-CG2 3.78Å; D339-T409 VanDerWaalsContact CG-CG2 3.46Å; D339-T409 WeakPolarHBondContact OD2-CG2 3.29Å; T409-D411 PolarHBondContact O-N 2.85Å; T409-W412 WeakPolarHBondContact O-CB 3.5Å; T409-W412 PolarHBondContact O-N 3.46Å; T409-W412 VanDerWaalsContact O-N 3.11Å; T409-W412 PolarHBondContact OG1-N 2.89Å; T409-F413 PolarHBondContact O-N 2.7Å
410D98.5Very high97.7Very high19 Ų1929.1 Ų29.110%0.10215%0.145CC..Hα-helixtrans-64.4-29.5178.9-167.957.6000113.1K308 Y387 E388 W390 F413 S414K308-D410 WeakPolarHBondContact CD-OD1 3.44Å; K308-D410 WeakPolarHBondContact CE-OD1 3.43Å; K308-D410 PolarHBondContact NZ-O 2.77Å; K308-D410 IonicContact NZ-OD1 2.71Å; K308-D410 PolarHBondContact NZ-OD1 3.1Å; K308-D410 IonicContact NZ-OD2 3.38Å; K308-D410 PolarHBondContact NZ-OD2 3.46Å; Y387-D410 WeakPolarHBondContact O-CB 3.37Å; E388-D410 PolarHBondContact O-N 2.87Å; W390-D410 PolarHBondContact NE1-OD1 3.48Å; D410-F413 WeakPolarHBondContact O-CB 3.27Å; D410-F413 PolarHBondContact O-N 2.9Å; D410-S414 PolarHBondContact O-N 2.88Å; D410-S414 PolarHBondContact O-OG 3.27Å; D410-S414 VanDerWaalsContact O-OG 3.08Å
411D98.4Very high98.1Very high97 Ų9723.3 Ų23.352%0.51912%0.123SC..Hα-helixtrans-66.7-40.7171.7-69.8-20.6000111.4M340 T409 F413 S414 E415M340-D411 HydrophobicContact CG-CB 3.92Å; T409-D411 PolarHBondContact O-N 2.85Å; D411-F413 VanDerWaalsContact C-N 3.32Å; D411-F413 PolarHBondContact O-N 2.95Å; D411-S414 VanDerWaalsContact O-CB 3.32Å; D411-S414 WeakPolarHBondContact O-CB 3.44Å; D411-S414 PolarHBondContact O-N 3.19Å; D411-E415 WeakPolarHBondContact O-CG 3.18Å; D411-E415 PolarHBondContact O-N 3.27Å; D411-E415 VanDerWaalsContact O-N 3.15Å
412W98.8Very high98.3Very high0 Ų022.4 Ų22.40%011%0.114CC..Hα-helixtrans-64.2-40.4174.9-166.7100.9000111.3C325 D326 K329 N338 M408 T409 S414 E415 Y416 V417C325-W412 HydrophobicContact CB-CH2 3.79Å; C325-W412 HydrophobicContact CB-CZ3 3.91Å; D326-W412 VanDerWaalsContact O-CZ2 3.3Å; D326-W412 WeakPolarHBondContact O-CZ2 3.47Å; K329-W412 PolarHBondContact O-NE1 3.44Å; N338-W412 HydrophobicContact CB-CD2 3.74Å; N338-W412 HydrophobicContact CB-CE3 4.27Å; N338-W412 HydrophobicContact CB-CG 3.89Å; N338-W412 HydrophobicContact CB-CZ2 4.28Å; N338-W412 WeakPolarHBondContact ND2-CZ2 3.45Å; M408-W412 HydrophobicContact CG-CB 4.21Å; M408-W412 HydrophobicContact CG-CD2 4.07Å; M408-W412 HydrophobicContact CG-CE3 3.45Å; M408-W412 VanDerWaalsContact CG-CE3 3.45Å; M408-W412 HydrophobicContact CG-CG 4.4Å; M408-W412 HydrophobicContact CG-CZ3 4.15Å; M408-W412 HydrophobicContact SD-CD2 4.37Å; M408-W412 HydrophobicContact SD-CE3 3.25Å; M408-W412 HydrophobicContact SD-CZ3 3.4Å; M408-W412 WeakPolarHBondContact SD-CZ3 3.42Å; T409-W412 WeakPolarHBondContact O-CB 3.5Å; T409-W412 PolarHBondContact O-N 3.46Å; T409-W412 VanDerWaalsContact O-N 3.11Å; T409-W412 PolarHBondContact OG1-N 2.89Å; W412-S414 VanDerWaalsContact C-N 3.29Å; W412-S414 PolarHBondContact O-N 2.93Å; W412-E415 PolarHBondContact O-N 3.08Å; W412-Y416 AromaticContact CD1-CD2 3.96Å; W412-Y416 HydrophobicContact CD2-CD2 4.22Å; W412-Y416 AromaticContact CE2-CD2 3.92Å; W412-Y416 HydrophobicContact CG-CD2 4.27Å; W412-Y416 HydrophobicContact CZ2-CD2 4.47Å; W412-Y416 HydrophobicContact CZ2-CG 4.43Å; W412-Y416 AromaticContact NE1-CD2 3.74Å; W412-Y416 PolarHBondContact O-N 3.35Å; W412-V417 HydrophobicContact CE3-CG2 4.34Å; W412-V417 HydrophobicContact CZ3-CG2 3.97Å
413F98.9Very high98.5Very high0 Ų020.2 Ų20.20%010%0.102CC..Hα-helixtrans-54.3-49.5172-166.4-53.9000110I304 L307 K308 L375 W390 M408 T409 D410 D411 E415 V417 V420I304-F413 HydrophobicContact CD1-CD1 3.92Å; I304-F413 HydrophobicContact CD1-CE1 3.8Å; I304-F413 HydrophobicContact CG1-CD1 4.34Å; L307-F413 HydrophobicContact CB-CE1 4.43Å; K308-F413 HydrophobicContact CD-CD1 4.35Å; K308-F413 HydrophobicContact CG-CD1 3.71Å; K308-F413 HydrophobicContact CG-CD2 4.42Å; K308-F413 HydrophobicContact CG-CE1 3.65Å; K308-F413 HydrophobicContact CG-CE2 4.35Å; K308-F413 HydrophobicContact CG-CG 4.15Å; K308-F413 HydrophobicContact CG-CZ 3.98Å; L375-F413 HydrophobicContact CD1-CE2 3.88Å; W390-F413 AromaticContact CD1-CD2 3.88Å; W390-F413 AromaticContact CD2-CD2 3.86Å; W390-F413 HydrophobicContact CD2-CD2 3.86Å; W390-F413 HydrophobicContact CD2-CE2 4.14Å; W390-F413 AromaticContact CE2-CD2 3.57Å; W390-F413 AromaticContact CE2-CE2 4Å; W390-F413 HydrophobicContact CE3-CE2 4.34Å; W390-F413 HydrophobicContact CG-CD2 4.07Å; W390-F413 HydrophobicContact CH2-CE2 4.33Å; W390-F413 HydrophobicContact CZ2-CD2 4.02Å; W390-F413 HydrophobicContact CZ2-CE2 4.11Å; W390-F413 HydrophobicContact CZ3-CE2 4.43Å; W390-F413 AromaticContact NE1-CD2 3.59Å; M408-F413 HydrophobicContact CE-CB 4.29Å; M408-F413 HydrophobicContact CE-CD2 3.48Å; M408-F413 VanDerWaalsContact CE-CD2 3.48Å; M408-F413 HydrophobicContact CE-CE2 4.18Å; M408-F413 HydrophobicContact CE-CG 4.22Å; T409-F413 PolarHBondContact O-N 2.7Å; D410-F413 WeakPolarHBondContact O-CB 3.27Å; D410-F413 PolarHBondContact O-N 2.9Å; D411-F413 VanDerWaalsContact C-N 3.32Å; D411-F413 PolarHBondContact O-N 2.95Å; F413-E415 VanDerWaalsContact C-N 3.28Å; F413-E415 PolarHBondContact O-N 3.03Å; F413-V417 HydrophobicContact CB-CG2 4.26Å; F413-V417 HydrophobicContact CD1-CB 3.64Å; F413-V417 HydrophobicContact CD1-CG1 4.01Å; F413-V417 HydrophobicContact CD1-CG2 3.87Å; F413-V417 HydrophobicContact CD2-CG2 4.15Å; F413-V417 HydrophobicContact CE1-CB 3.75Å; F413-V417 HydrophobicContact CE1-CG1 3.56Å; F413-V417 HydrophobicContact CE1-CG2 4.21Å; F413-V417 HydrophobicContact CE2-CG2 4.49Å; F413-V417 HydrophobicContact CG-CB 4.13Å; F413-V417 HydrophobicContact CG-CG2 3.81Å; F413-V417 HydrophobicContact CZ-CB 4.35Å; F413-V417 HydrophobicContact CZ-CG1 3.86Å; F413-V417 WeakPolarHBondContact O-CB 3.28Å; F413-V417 PolarHBondContact O-N 2.71Å; F413-V417 VanDerWaalsContact O-N 3.11Å; F413-V420 HydrophobicContact CZ-CG1 3.87Å
414S98.8Very high98.6Very high28 Ų2818 Ų1820%0.1969%0.092CC..Hα-helixtrans-53-46.8179.4-57.90000112.5K308 K358 D410 D411 W412K308-S414 PolarHBondContact NZ-OG 2.81Å; K358-S414 WeakPolarHBondContact CD-O 3.32Å; K358-S414 PolarHBondContact NZ-O 3.07Å; D410-S414 PolarHBondContact O-N 2.88Å; D410-S414 PolarHBondContact O-OG 3.27Å; D410-S414 VanDerWaalsContact O-OG 3.08Å; D411-S414 VanDerWaalsContact O-CB 3.32Å; D411-S414 WeakPolarHBondContact O-CB 3.44Å; D411-S414 PolarHBondContact O-N 3.19Å; W412-S414 VanDerWaalsContact C-N 3.29Å; W412-S414 PolarHBondContact O-N 2.93Å
415E98.8Very high98.6Very high60 Ų6024.8 Ų24.828%0.2812%0.117SC..Hα-helixtrans-82.2-35.3-169.7-68-59.9135.800114M340 K358 R361 D411 W412 F413M340-E415 HydrophobicContact CE-CB 4.31Å; M340-E415 HydrophobicContact CE-CG 3.9Å; M340-E415 HydrophobicContact CG-CG 4.47Å; M340-E415 HydrophobicContact SD-CB 3.92Å; M340-E415 HydrophobicContact SD-CG 3.86Å; K358-E415 WeakPolarHBondContact CD-O 3.4Å; K358-E415 WeakPolarHBondContact CE-O 3.18Å; K358-E415 WeakPolarHBondContact CG-O 3.41Å; R361-E415 IonicContact CZ-OE2 2.95Å; R361-E415 VanDerWaalsContact CZ-OE2 3.24Å; R361-E415 IonicContact NH1-OE2 3.79Å; R361-E415 PolarHBondContact NH1-OE2 3.47Å; R361-E415 PolarHBondContact NH2-O 3.23Å; R361-E415 IonicContact NH2-OE2 3.78Å; R361-E415 PolarHBondContact NH2-OE2 2.92Å; D411-E415 WeakPolarHBondContact O-CG 3.18Å; D411-E415 PolarHBondContact O-N 3.27Å; D411-E415 VanDerWaalsContact O-N 3.15Å; W412-E415 PolarHBondContact O-N 3.08Å; F413-E415 VanDerWaalsContact C-N 3.28Å; F413-E415 PolarHBondContact O-N 3.03Å
416Y98.8Very high98.6Very high4 Ų425.6 Ų25.62%0.01612%0.121CC..Hα-helixtrans-130.1-3.4-165.5-61.5-64.3000115.8C325 D326 K329 H330 M340 W412 Y418C325-Y416 CarbonylContact C-O 3.12Å; C325-Y416 WeakPolarHBondContact CA-O 3.46Å; C325-Y416 WeakPolarHBondContact CB-O 3.46Å; D326-Y416 HydrophobicContact CB-CD1 4.28Å; D326-Y416 PolarHBondContact N-O 3.02Å; K329-Y416 HydrophobicContact CB-CD1 3.64Å; K329-Y416 HydrophobicContact CB-CD2 3.92Å; K329-Y416 HydrophobicContact CB-CE1 3.49Å; K329-Y416 VanDerWaalsContact CB-CE1 3.49Å; K329-Y416 HydrophobicContact CB-CE2 3.75Å; K329-Y416 HydrophobicContact CB-CG 3.87Å; K329-Y416 HydrophobicContact CD-CE1 4.35Å; K329-Y416 HydrophobicContact CG-CD1 3.77Å; K329-Y416 HydrophobicContact CG-CE1 3.55Å; K329-Y416 HydrophobicContact CG-CG 4.47Å; H330-Y416 AromaticContact CD2-CE2 3.45Å; H330-Y416 VanDerWaalsContact CD2-CE2 3.45Å; H330-Y416 WeakPolarHBondContact CD2-CE2 3.45Å; H330-Y416 AromaticContact CD2-CZ 3.66Å; H330-Y416 PolarHBondContact CD2-OH 2.94Å; H330-Y416 PolarHBondContact NE2-OH 3.13Å; M340-Y416 HydrophobicContact CE-CE2 3.86Å; M340-Y416 HydrophobicContact SD-CD2 3.95Å; M340-Y416 HydrophobicContact SD-CE2 3.46Å; M340-Y416 WeakPolarHBondContact SD-CE2 3.31Å; W412-Y416 AromaticContact CD1-CD2 3.96Å; W412-Y416 HydrophobicContact CD2-CD2 4.22Å; W412-Y416 AromaticContact CE2-CD2 3.92Å; W412-Y416 HydrophobicContact CG-CD2 4.27Å; W412-Y416 HydrophobicContact CZ2-CD2 4.47Å; W412-Y416 HydrophobicContact CZ2-CG 4.43Å; W412-Y416 AromaticContact NE1-CD2 3.74Å; W412-Y416 PolarHBondContact O-N 3.35Å; Y416-Y418 WeakPolarHBondContact O-CD2 3.32Å; Y416-Y418 WeakPolarHBondContact O-CE2 3.4Å
417V98.9Very high98.6Very high0 Ų026.2 Ų26.20%012%0.124CC..EExtended strand (participates in β ladder)trans-85.8127.1166.61750000109.4F323 C325 K358 M408 W412 F413 V420F323-V417 HydrophobicContact CD2-CG1 4.13Å; F323-V417 HydrophobicContact CD2-CG2 3.92Å; F323-V417 HydrophobicContact CE2-CG2 3.99Å; C325-V417 HydrophobicContact CB-CG2 4.2Å; K358-V417 PolarHBondContact NZ-O 3.19Å; M408-V417 HydrophobicContact CE-CG2 4.32Å; M408-V417 HydrophobicContact SD-CG2 3.93Å; W412-V417 HydrophobicContact CE3-CG2 4.34Å; W412-V417 HydrophobicContact CZ3-CG2 3.97Å; F413-V417 HydrophobicContact CB-CG2 4.26Å; F413-V417 HydrophobicContact CD1-CB 3.64Å; F413-V417 HydrophobicContact CD1-CG1 4.01Å; F413-V417 HydrophobicContact CD1-CG2 3.87Å; F413-V417 HydrophobicContact CD2-CG2 4.15Å; F413-V417 HydrophobicContact CE1-CB 3.75Å; F413-V417 HydrophobicContact CE1-CG1 3.56Å; F413-V417 HydrophobicContact CE1-CG2 4.21Å; F413-V417 HydrophobicContact CE2-CG2 4.49Å; F413-V417 HydrophobicContact CG-CB 4.13Å; F413-V417 HydrophobicContact CG-CG2 3.81Å; F413-V417 HydrophobicContact CZ-CB 4.35Å; F413-V417 HydrophobicContact CZ-CG1 3.86Å; F413-V417 WeakPolarHBondContact O-CB 3.28Å; F413-V417 PolarHBondContact O-N 2.71Å; F413-V417 VanDerWaalsContact O-N 3.11Å; V417-V420 HydrophobicContact CG1-CG1 4.1Å
418Y98.8Very high98.6Very high1 Ų128.2 Ų28.20%0.00414%0.138CC..EExtended strand (participates in β ladder)trans-111.4-24.2-177.6-67-77.4000113V270 N271 G324 D326 K358 L362 S367 M369 Y416 M448V270-Y418 CarbonylContact C-O 3.58Å; V270-Y418 WeakPolarHBondContact CA-O 3.48Å; V270-Y418 WeakPolarHBondContact CB-O 3.46Å; N271-Y418 PolarHBondContact N-O 2.84Å; G324-Y418 PolarHBondContact O-N 2.86Å; D326-Y418 HydrophobicContact CB-CE2 4.11Å; K358-Y418 HydrophobicContact CD-CE1 4.36Å; K358-Y418 VanDerWaalsContact CE-CE1 3.45Å; K358-Y418 HydrophobicContact CG-CE1 4.05Å; L362-Y418 HydrophobicContact CD1-CD1 4.36Å; L362-Y418 HydrophobicContact CD1-CE1 3.8Å; L362-Y418 HydrophobicContact CD2-CD1 4.3Å; L362-Y418 HydrophobicContact CD2-CE1 3.69Å; L362-Y418 HydrophobicContact CG-CE1 3.84Å; S367-Y418 WeakPolarHBondContact CB-OH 3.38Å; S367-Y418 PolarHBondContact OG-OH 3.08Å; M369-Y418 HydrophobicContact CB-CD2 4.14Å; Y416-Y418 WeakPolarHBondContact O-CD2 3.32Å; Y416-Y418 WeakPolarHBondContact O-CE2 3.4Å; Y418-M448 HydrophobicContact CD1-SD 4.38Å
419E98.6Very high98.5Very high0 Ų032.7 Ų32.70%017%0.167CC..EExtended strand (participates in β ladder)trans-145.6139.5-172.7-171.7-176171.300110.4Q145 C268 L269 V270 W322 F323 G324 M369Q145-E419 PolarHBondContact OE1-OE2 2.8Å; C268-E419 VanDerWaalsContact SG-CD 3.57Å; C268-E419 VanDerWaalsContact SG-CG 3.59Å; C268-E419 PolarHBondContact SG-OE1 3.44Å; L269-E419 CarbonylContact O-C 3.57Å; L269-E419 VanDerWaalsContact O-CA 3.27Å; L269-E419 WeakPolarHBondContact O-CA 3.33Å; V270-E419 HydrophobicContact CG1-CB 4.22Å; V270-E419 HydrophobicContact CG1-CG 3.99Å; W322-E419 WeakPolarHBondContact CH2-OE2 3.17Å; W322-E419 HydrophobicContact CZ3-CB 4.3Å; W322-E419 HydrophobicContact CZ3-CG 3.78Å; W322-E419 WeakPolarHBondContact CZ3-OE1 3.35Å; F323-E419 CarbonylContact C-O 2.85Å; F323-E419 WeakPolarHBondContact CA-O 3.45Å; F323-E419 VanDerWaalsContact CB-O 3.23Å; F323-E419 WeakPolarHBondContact CB-O 3.38Å; G324-E419 PolarHBondContact N-O 3.28Å; G324-E419 PolarHBondContact O-N 2.94Å; M369-E419 WeakPolarHBondContact CE-OE2 3.4Å; M369-E419 HydrophobicContact SD-CB 3.98Å; M369-E419 VanDerWaalsContact SD-OE2 3.33Å
420V98.9Very high98.5Very high0 Ų036.4 Ų36.40%019%0.186CC..EExtended strand (participates in β ladder)trans-134.8147.7166.4-60.30000109.7L269 L307 V321 F323 F413 V417L269-V420 HydrophobicContact CB-CG2 4.03Å; L269-V420 HydrophobicContact CD1-CG2 4.47Å; L269-V420 PolarHBondContact N-O 3.41Å; L269-V420 PolarHBondContact O-N 3.22Å; L307-V420 HydrophobicContact CB-CG1 4.45Å; L307-V420 HydrophobicContact CB-CG2 3.76Å; L307-V420 HydrophobicContact CD2-CG1 4.49Å; L307-V420 HydrophobicContact CD2-CG2 4.02Å; L307-V420 HydrophobicContact CG-CG2 3.68Å; V321-V420 HydrophobicContact CG1-CB 4.07Å; F323-V420 HydrophobicContact CB-CG1 3.91Å; F413-V420 HydrophobicContact CZ-CG1 3.87Å; V417-V420 HydrophobicContact CG1-CG1 4.1Å
421V98.9Very high98.5Very high1 Ų135.7 Ų35.71%0.00618%0.182CC..EExtended strand (participates in β ladder)trans-120.6120.4177.6174.20000109.3W146 K266 V267 C268 W322W146-V421 HydrophobicContact CB-CG2 3.92Å; W146-V421 HydrophobicContact CD2-CB 4.17Å; W146-V421 HydrophobicContact CD2-CG1 3.59Å; W146-V421 HydrophobicContact CD2-CG2 3.7Å; W146-V421 VanDerWaalsContact CE2-CG1 3.42Å; W146-V421 HydrophobicContact CE3-CB 4.19Å; W146-V421 HydrophobicContact CE3-CG1 3.88Å; W146-V421 HydrophobicContact CE3-CG2 3.88Å; W146-V421 HydrophobicContact CG-CG1 4.16Å; W146-V421 HydrophobicContact CG-CG2 3.68Å; W146-V421 HydrophobicContact CH2-CG1 3.84Å; W146-V421 HydrophobicContact CZ2-CG1 3.56Å; W146-V421 HydrophobicContact CZ3-CB 4.48Å; W146-V421 HydrophobicContact CZ3-CG1 3.99Å; K266-V421 HydrophobicContact CB-CG1 3.66Å; V267-V421 WeakPolarHBondContact O-CA 3.37Å; C268-V421 HydrophobicContact CB-CG2 4.24Å; W322-V421 HydrophobicContact CB-CB 4.31Å; W322-V421 HydrophobicContact CD2-CG2 4.34Å; W322-V421 HydrophobicContact CE3-CB 4.13Å; W322-V421 HydrophobicContact CE3-CG2 3.5Å; W322-V421 HydrophobicContact CZ3-CG2 3.96Å; W322-V421 PolarHBondContact O-N 3.39Å
422V98.8Very high98.5Very high0 Ų033.6 Ų33.60%017%0.171CC..EExtended strand (participates in β ladder)trans-132.5158.8-176.5-64.90000110.7K266 V267 A310 V321 F426 L427K266-V422 CarbonylContact C-O 3.59Å; K266-V422 WeakPolarHBondContact CA-O 3.33Å; V267-V422 PolarHBondContact N-O 2.8Å; V267-V422 PolarHBondContact O-N 3.5Å; A310-V422 HydrophobicContact CB-CG1 4.33Å; A310-V422 HydrophobicContact CB-CG2 4.07Å; V321-V422 HydrophobicContact CG1-CG1 3.95Å; V321-V422 HydrophobicContact CG2-CG1 4.27Å; V422-F426 HydrophobicContact CB-CD2 4.38Å; V422-L427 HydrophobicContact CG2-CD1 4.18Å; V422-L427 HydrophobicContact CG2-CD2 3.73Å; V422-L427 HydrophobicContact CG2-CG 4.03Å
423D98.7Very high98.5Very high20 Ų2039.2 Ų39.211%0.10720%0.197CC..EExtended strand (participates in β ladder)trans-62.5138.6170.6-163.7-78.3000111.5K266 R425 F426K266-D423 HydrophobicContact CD-CB 4.09Å; K266-D423 IonicContact NZ-OD2 2.81Å; K266-D423 PolarHBondContact NZ-OD2 3.07Å; D423-R425 HydrophobicContact CB-CG 4.03Å; D423-R425 PolarHBondContact O-N 3.24Å; D423-R425 WeakPolarHBondContact OD1-CB 3.41Å; D423-R425 WeakPolarHBondContact OD1-CD 3.48Å; D423-R425 WeakPolarHBondContact OD1-CG 3.46Å; D423-R425 PolarHBondContact OD1-N 3.34Å; D423-F426 HydrophobicContact CB-CD2 3.7Å; D423-F426 HydrophobicContact CB-CE2 3.7Å; D423-F426 WeakPolarHBondContact O-CD2 3.44Å; D423-F426 PolarHBondContact O-N 3.12Å
424K98.3Very high98.5Very high96 Ų9639.5 Ų39.542%0.41720%0.199SC..G310 helixtrans-53.1-25.3178.268.4-170.2-175.8-165.80113.7D265 V267 F426 L427 L432D265-K424 HydrophobicContact CB-CD 4.4Å; D265-K424 WeakPolarHBondContact O-CB 3.37Å; D265-K424 PolarHBondContact O-N 3.11Å; D265-K424 WeakPolarHBondContact OD1-CE 3.42Å; D265-K424 IonicContact OD1-NZ 3.28Å; D265-K424 PolarHBondContact OD1-NZ 3.41Å; V267-K424 HydrophobicContact CG2-CB 3.94Å; K424-F426 PolarHBondContact O-N 3.25Å; K424-L427 PolarHBondContact O-N 3.33Å; K424-L427 VanDerWaalsContact O-N 3.13Å; K424-L432 HydrophobicContact CB-CD2 3.82Å
425R97.8Very high98.4Very high146 Ų14640.7 Ų40.755%0.55120%0.202SC*.G310 helixtrans-64.7-18.8177.376.3-166.6178.4143.5-2.4114.2D423 L427D423-R425 HydrophobicContact CB-CG 4.03Å; D423-R425 PolarHBondContact O-N 3.24Å; D423-R425 WeakPolarHBondContact OD1-CB 3.41Å; D423-R425 WeakPolarHBondContact OD1-CD 3.48Å; D423-R425 WeakPolarHBondContact OD1-CG 3.46Å; D423-R425 PolarHBondContact OD1-N 3.34Å; R425-L427 VanDerWaalsContact C-N 3.33Å
426F98Very high98.3Very high29 Ų2945.8 Ų45.813%0.12723%0.226CC..G310 helixtrans-90.30.3176.9-58.3-61000113.2D313 E317 V422 D423 K424D313-F426 HydrophobicContact CB-CD1 3.94Å; E317-F426 HydrophobicContact CB-CE1 3.77Å; E317-F426 HydrophobicContact CB-CZ 3.73Å; E317-F426 HydrophobicContact CG-CE1 3.68Å; E317-F426 HydrophobicContact CG-CZ 4.16Å; V422-F426 HydrophobicContact CB-CD2 4.38Å; D423-F426 HydrophobicContact CB-CD2 3.7Å; D423-F426 HydrophobicContact CB-CE2 3.7Å; D423-F426 WeakPolarHBondContact O-CD2 3.44Å; D423-F426 PolarHBondContact O-N 3.12Å; K424-F426 PolarHBondContact O-N 3.25Å
427L98.4Very high98.3Very high14 Ų1448.9 Ų48.97%0.07324%0.24CC..SBendtrans-110.6137.2-174.2-58.3-175.6000110.5V267 L269 A310 V422 K424 R425 V431 L432V267-L427 HydrophobicContact CB-CD1 3.57Å; V267-L427 HydrophobicContact CG1-CD1 3.65Å; V267-L427 HydrophobicContact CG2-CD1 3.99Å; L269-L427 HydrophobicContact CD1-CD2 3.68Å; L269-L427 HydrophobicContact CD2-CD1 4.13Å; L269-L427 HydrophobicContact CG-CD1 4.44Å; L269-L427 HydrophobicContact CG-CD2 4.44Å; A310-L427 HydrophobicContact CB-CD2 3.78Å; V422-L427 HydrophobicContact CG2-CD1 4.18Å; V422-L427 HydrophobicContact CG2-CD2 3.73Å; V422-L427 HydrophobicContact CG2-CG 4.03Å; K424-L427 PolarHBondContact O-N 3.33Å; K424-L427 VanDerWaalsContact O-N 3.13Å; R425-L427 VanDerWaalsContact C-N 3.33Å; L427-V431 HydrophobicContact CB-CG1 4.38Å; L427-V431 HydrophobicContact CD1-CG1 4.25Å; L427-L432 HydrophobicContact CB-CD2 3.85Å; L427-L432 HydrophobicContact CB-CG 4.01Å; L427-L432 HydrophobicContact CD1-CD2 3.9Å; L427-L432 HydrophobicContact CG-CD2 4.46Å
428P97.8Very high98.3Very high51 Ų5157.8 Ų57.833%0.33128%0.282SS..  trans-68.9155.8174.932.3-36.4000110.6L306 D430 V431 L432L306-P428 HydrophobicContact CD1-CG 4.48Å; P428-D430 VanDerWaalsContact C-N 3.3Å; P428-D430 VanDerWaalsContact CB-OD1 3.22Å; P428-D430 WeakPolarHBondContact CB-OD1 3.45Å; P428-D430 VanDerWaalsContact CG-OD1 3.27Å; P428-D430 WeakPolarHBondContact CG-OD1 3.45Å; P428-D430 PolarHBondContact O-N 3Å; P428-V431 HydrophobicContact CG-CB 4.03Å; P428-V431 HydrophobicContact CG-CG2 3.57Å; P428-V431 PolarHBondContact O-N 3.32Å; P428-V431 VanDerWaalsContact O-N 3.12Å; P428-L432 PolarHBondContact O-N 3.1Å
429P98.1Very high98.3Very high95 Ų9558.5 Ų58.562%0.61729%0.288SS*.Hα-helixtrans-56.8-38.5-174-27.935.8000114.6V431 L432 E433P429-V431 VanDerWaalsContact C-N 3.31Å; P429-V431 PolarHBondContact O-N 3.24Å; P429-L432 WeakPolarHBondContact O-CB 3.47Å; P429-L432 PolarHBondContact O-N 3.17Å; P429-L432 VanDerWaalsContact O-N 3.11Å; P429-E433 WeakPolarHBondContact O-CG 3.27Å; P429-E433 PolarHBondContact O-N 3.36Å
430D97.9Very high98.3Very high103 Ų10362.1 Ų62.155%0.55131%0.31SS*.Hα-helixtrans-62.8-35.7178.963.3-41.8000112.5P428P428-D430 VanDerWaalsContact C-N 3.3Å; P428-D430 VanDerWaalsContact CB-OD1 3.22Å; P428-D430 WeakPolarHBondContact CB-OD1 3.45Å; P428-D430 VanDerWaalsContact CG-OD1 3.27Å; P428-D430 WeakPolarHBondContact CG-OD1 3.45Å; P428-D430 PolarHBondContact O-N 3Å
431V98.4Very high98.3Very high4 Ų465.5 Ų65.52%0.02433%0.33CS..Hα-helixtrans-69.9-38.2173.8173.60000110.7L269 N300 Q302 L306 L427 P428 P429 V434L269-V431 HydrophobicContact CD2-CG1 3.86Å; N300-V431 PolarHBondContact ND2-O 2.93Å; Q302-V431 HydrophobicContact CG-CG1 4.39Å; L306-V431 HydrophobicContact CD1-CG2 4.29Å; L306-V431 HydrophobicContact CD2-CG1 4.09Å; L306-V431 HydrophobicContact CD2-CG2 3.65Å; L427-V431 HydrophobicContact CB-CG1 4.38Å; L427-V431 HydrophobicContact CD1-CG1 4.25Å; P428-V431 HydrophobicContact CG-CB 4.03Å; P428-V431 HydrophobicContact CG-CG2 3.57Å; P428-V431 PolarHBondContact O-N 3.32Å; P428-V431 VanDerWaalsContact O-N 3.12Å; P429-V431 VanDerWaalsContact C-N 3.31Å; P429-V431 PolarHBondContact O-N 3.24Å; V431-V434 WeakPolarHBondContact O-CB 3.22Å; V431-V434 PolarHBondContact O-N 2.94Å
432L98.3Very high98.2Very high54 Ų5466.1 Ų66.128%0.28333%0.333SS..Hα-helixtrans-68.6-35.2177.3-65.5176.1000112.4V267 K424 L427 P428 P429 V434 M435V267-L432 HydrophobicContact CG2-CD2 3.99Å; K424-L432 HydrophobicContact CB-CD2 3.82Å; L427-L432 HydrophobicContact CB-CD2 3.85Å; L427-L432 HydrophobicContact CB-CG 4.01Å; L427-L432 HydrophobicContact CD1-CD2 3.9Å; L427-L432 HydrophobicContact CG-CD2 4.46Å; P428-L432 PolarHBondContact O-N 3.1Å; P429-L432 WeakPolarHBondContact O-CB 3.47Å; P429-L432 PolarHBondContact O-N 3.17Å; P429-L432 VanDerWaalsContact O-N 3.11Å; L432-V434 PolarHBondContact O-N 3.24Å; L432-M435 WeakPolarHBondContact O-CB 3.21Å; L432-M435 PolarHBondContact O-N 3.45Å
433E98.3Very high98.2Very high118 Ų11868.6 Ų68.655%0.55135%0.35SS*.Hα-helixtrans-60.4-27.3175.4-76.2173.9-171.800112.6P429 M435 Q436P429-E433 WeakPolarHBondContact O-CG 3.27Å; P429-E433 PolarHBondContact O-N 3.36Å; E433-M435 PolarHBondContact O-N 2.99Å; E433-Q436 WeakPolarHBondContact O-CB 3.35Å; E433-Q436 PolarHBondContact O-N 2.94Å
434V98.6Very high98.2Very high6 Ų667.9 Ų67.94%0.03635%0.346CS..G310 helixtrans-57.9-33.6173.7-179.40000111.8K281 L282 N300 V431 L432 Q436 Q437K281-V434 VanDerWaalsContact C-CG1 3.41Å; L282-V434 HydrophobicContact CB-CG1 4.05Å; L282-V434 HydrophobicContact CD1-CG1 4.49Å; N300-V434 WeakPolarHBondContact OD1-CG1 3.32Å; V431-V434 WeakPolarHBondContact O-CB 3.22Å; V431-V434 PolarHBondContact O-N 2.94Å; L432-V434 PolarHBondContact O-N 3.24Å; V434-Q436 PolarHBondContact O-N 3.32Å; V434-Q436 VanDerWaalsContact O-N 3.12Å; V434-Q437 WeakPolarHBondContact O-CB 3.33Å; V434-Q437 WeakPolarHBondContact O-CG 3.41Å; V434-Q437 PolarHBondContact O-N 3.14Å; V434-Q437 VanDerWaalsContact O-N 3.1Å
435M97.6Very high98.2Very high53 Ų5367.3 Ų67.326%0.26134%0.342SS..G310 helixtrans-67.4-11.6179.1-61.7-60.1-63.200113.6V267 L282 L298 N300 L432 E433V267-M435 HydrophobicContact CG1-CG 4.17Å; V267-M435 HydrophobicContact CG1-SD 4.02Å; L282-M435 HydrophobicContact CD1-CE 4.32Å; L282-M435 HydrophobicContact CD1-SD 3.71Å; L298-M435 HydrophobicContact CB-CE 4.21Å; L298-M435 HydrophobicContact CD1-CE 4.22Å; N300-M435 HydrophobicContact CB-SD 3.91Å; L432-M435 WeakPolarHBondContact O-CB 3.21Å; L432-M435 PolarHBondContact O-N 3.45Å; E433-M435 PolarHBondContact O-N 2.99Å
436Q97.4Very high98.2Very high167 Ų16761.2 Ų61.278%0.7832%0.32SS*.G310 helixtrans-94.5-7.1177.1-56.2-179.30.400112.8E433 V434E433-Q436 WeakPolarHBondContact O-CB 3.35Å; E433-Q436 PolarHBondContact O-N 2.94Å; V434-Q436 PolarHBondContact O-N 3.32Å; V434-Q436 VanDerWaalsContact O-N 3.12Å
437Q98.4Very high98.2Very high68 Ų6861.1 Ų61.132%0.31832%0.322SS..SBendtrans-71.1157.9178.8-61.7179.117.100111.3G280 L282 V434 A439G280-Q437 PolarHBondContact O-NE2 3.19Å; G280-Q437 VanDerWaalsContact O-NE2 3.09Å; L282-Q437 HydrophobicContact CB-CB 4.14Å; L282-Q437 VanDerWaalsContact CD2-O 3.28Å; L282-Q437 WeakPolarHBondContact CD2-O 3.18Å; V434-Q437 WeakPolarHBondContact O-CB 3.33Å; V434-Q437 WeakPolarHBondContact O-CG 3.41Å; V434-Q437 PolarHBondContact O-N 3.14Å; V434-Q437 VanDerWaalsContact O-N 3.1Å; Q437-A439 PolarHBondContact O-N 3.44Å
438E98.1Very high98.2Very high188 Ų18860.6 Ų60.688%0.87932%0.32SS*.PPolyproline II helixtrans-70.1125.6162.3-173.7173.6-17400109.2
439A98.4Very high97.9Very high16 Ų1658.7 Ų58.713%0.13231%0.309CS..PPolyproline II helixtrans-73.3132.7-17600000111.8L282 L298 Q437 V441L282-A439 HydrophobicContact CB-CB 4.42Å; L282-A439 HydrophobicContact CD2-CB 4.03Å; L282-A439 HydrophobicContact CG-CB 3.99Å; L282-A439 CarbonylContact O-C 3.59Å; L282-A439 WeakPolarHBondContact O-CA 3.4Å; L298-A439 HydrophobicContact CD2-CB 3.9Å; Q437-A439 PolarHBondContact O-N 3.44Å; A439-V441 PolarHBondContact O-N 3.36Å
440V98.6Very high97.2Very high75 Ų7556 Ų5646%0.45529%0.293SS..EExtended strand (participates in β ladder)trans-68.4121.2168.1179.80000108.6L282 Y283 S284 L442L282-V440 PolarHBondContact O-N 2.92Å; Y283-V440 CarbonylContact C-O 3.5Å; Y283-V440 WeakPolarHBondContact CA-O 3.29Å; Y283-V440 HydrophobicContact CD1-CB 3.73Å; Y283-V440 HydrophobicContact CD1-CG1 4.08Å; Y283-V440 HydrophobicContact CE1-CB 3.96Å; Y283-V440 HydrophobicContact CE1-CG1 4.15Å; Y283-V440 HydrophobicContact CE1-CG2 4.36Å; S284-V440 PolarHBondContact N-O 3.17Å; V440-L442 PolarHBondContact O-N 2.79Å
441V98.6Very high96.4Very high71 Ų7151.3 Ų51.343%0.4327%0.268SS..EExtended strand (participates in β ladder)trans-87.4111.5-178.6-175.20000110S284 E286 A439S284-V441 CarbonylContact O-C 3.59Å; S284-V441 WeakPolarHBondContact O-CA 3.35Å; E286-V441 HydrophobicContact CB-CG1 3.9Å; E286-V441 HydrophobicContact CG-CG1 4.32Å; A439-V441 PolarHBondContact O-N 3.36Å
442L98.6Very high94.1Very high15 Ų1554 Ų548%0.07929%0.29CS..EExtended strand (participates in β ladder)trans-81.1154.2173.6-57.8177.2000110.7Y283 S284 V285 E286 V440 D446Y283-L442 HydrophobicContact CD1-CD1 4.2Å; Y283-L442 HydrophobicContact CD1-CD2 3.99Å; Y283-L442 HydrophobicContact CD1-CG 4.14Å; S284-L442 PolarHBondContact O-N 2.74Å; V285-L442 HydrophobicContact CG2-CB 4.28Å; V285-L442 HydrophobicContact CG2-CD1 4.37Å; E286-L442 WeakPolarHBondContact CB-O 3.41Å; E286-L442 PolarHBondContact N-O 3.5Å; V440-L442 PolarHBondContact O-N 2.79Å; L442-D446 HydrophobicContact CB-CB 3.94Å
443P98.4Very high93.9Very high52 Ų5254 Ų5434%0.33829%0.29SS..  trans-59.1150.8177.6-21.932.9000112.7V285 W445 D446V285-P443 WeakPolarHBondContact CG1-O 3.43Å; P443-W445 HydrophobicContact CB-CD2 4.05Å; P443-W445 HydrophobicContact CB-CH2 4.21Å; P443-W445 HydrophobicContact CB-CZ2 3.65Å; P443-W445 HydrophobicContact CG-CZ2 4.39Å; P443-W445 PolarHBondContact O-N 3.34Å; P443-D446 WeakPolarHBondContact O-CB 3.42Å; P443-D446 PolarHBondContact O-N 2.87Å
444A98.2Very high93.7Very high5 Ų550.6 Ų50.64%0.04128%0.276CS..THydrogen-bonded Turntrans-55.4-30.5-176.300000115L131 F134 E286 D446L131-A444 HydrophobicContact CD1-CB 3.68Å; F134-A444 HydrophobicContact CD1-CB 3.73Å; F134-A444 VanDerWaalsContact CE1-C 3.41Å; F134-A444 HydrophobicContact CE1-CB 3.74Å; F134-A444 WeakPolarHBondContact CE1-O 3.33Å; F134-A444 WeakPolarHBondContact CZ-O 3.33Å; E286-A444 HydrophobicContact CB-CB 4.3Å; E286-A444 WeakPolarHBondContact O-CA 3.39Å; E286-A444 WeakPolarHBondContact O-CB 3.36Å; A444-D446 VanDerWaalsContact C-N 3.35Å
445W98Very high93.4Very high83 Ų8353.1 Ų53.131%0.31429%0.29SS..THydrogen-bonded Turntrans-91.213.2178.857.775.2000114R130 L131 F134 P443R130-W445 HydrophobicContact CB-CH2 4.41Å; R130-W445 HydrophobicContact CB-CZ3 4.27Å; R130-W445 HydrophobicContact CG-CD2 4.18Å; R130-W445 HydrophobicContact CG-CE3 3.9Å; R130-W445 HydrophobicContact CG-CH2 4.07Å; R130-W445 HydrophobicContact CG-CZ2 4.34Å; R130-W445 HydrophobicContact CG-CZ3 3.85Å; R130-W445 VanDerWaalsContact CZ-CE2 3.42Å; R130-W445 VanDerWaalsContact NE-CE2 3.28Å; R130-W445 VanDerWaalsContact NH2-CD1 3.27Å; L131-W445 HydrophobicContact CB-CZ3 4.08Å; L131-W445 HydrophobicContact CD1-CZ3 4.39Å; F134-W445 HydrophobicContact CB-CE3 4.46Å; F134-W445 HydrophobicContact CD1-CB 4.5Å; F134-W445 HydrophobicContact CD2-CB 3.63Å; F134-W445 HydrophobicContact CE2-CB 3.78Å; F134-W445 HydrophobicContact CG-CB 4.02Å; F134-W445 HydrophobicContact CZ-CB 4.29Å; P443-W445 HydrophobicContact CB-CD2 4.05Å; P443-W445 HydrophobicContact CB-CH2 4.21Å; P443-W445 HydrophobicContact CB-CZ2 3.65Å; P443-W445 HydrophobicContact CG-CZ2 4.39Å; P443-W445 PolarHBondContact O-N 3.34Å
446D98.6Very high93.2Very high18 Ų1853.1 Ų53.110%0.09629%0.291CS..  trans-62.1137178.6-168.1-82.2000111.2R274 V285 L442 P443 A444 M448 G449R274-D446 IonicContact CZ-OD1 3.92Å; R274-D446 IonicContact CZ-OD2 3.8Å; R274-D446 IonicContact NH1-OD1 2.67Å; R274-D446 PolarHBondContact NH1-OD1 2.89Å; R274-D446 IonicContact NH1-OD2 3.24Å; R274-D446 PolarHBondContact NH1-OD2 2.86Å; R274-D446 IonicContact NH2-OD1 3.5Å; R274-D446 PolarHBondContact NH2-OD1 3.48Å; R274-D446 IonicContact NH2-OD2 2.65Å; R274-D446 PolarHBondContact NH2-OD2 3.23Å; V285-D446 HydrophobicContact CG1-CB 4.44Å; L442-D446 HydrophobicContact CB-CB 3.94Å; P443-D446 WeakPolarHBondContact O-CB 3.42Å; P443-D446 PolarHBondContact O-N 2.87Å; A444-D446 VanDerWaalsContact C-N 3.35Å; D446-M448 PolarHBondContact O-N 3.09Å; D446-M448 VanDerWaalsContact O-N 3.12Å; D446-M448 WeakPolarHBondContact OD1-CB 3.28Å; D446-M448 PolarHBondContact OD1-N 3.12Å; D446-G449 PolarHBondContact O-N 3.03Å
447P97.8Very high92.9Very high28 Ų2845.9 Ų45.918%0.18226%0.261CS..G310 helixtrans-62.1-21.4-176.525.4-37000114L362 L368 G449 S450L362-P447 HydrophobicContact CD2-CB 4.01Å; L362-P447 HydrophobicContact CD2-CG 4.16Å; L368-P447 HydrophobicContact CB-CB 3.97Å; P447-G449 PolarHBondContact O-N 3.23Å; P447-S450 PolarHBondContact O-N 3.44Å
448M97.4Very high92.6Very high3 Ų344.5 Ų44.52%0.01526%0.257CS..G310 helixtrans-73.5-7.3174.1-63.6-58.3-61.100112.9V270 D272 R274 Y299 L362 Y418 D446V270-M448 HydrophobicContact CB-CE 3.74Å; V270-M448 HydrophobicContact CG1-CE 4.02Å; V270-M448 HydrophobicContact CG2-CE 4.14Å; D272-M448 HydrophobicContact CB-CE 4.19Å; D272-M448 HydrophobicContact CB-CG 4.25Å; D272-M448 HydrophobicContact CB-SD 4.05Å; R274-M448 VanDerWaalsContact NH2-CG 3.34Å; Y299-M448 HydrophobicContact CD2-CB 4.43Å; Y299-M448 HydrophobicContact CE2-CB 4.13Å; Y299-M448 WeakPolarHBondContact CE2-O 3.36Å; Y299-M448 VanDerWaalsContact CZ-O 3.23Å; Y299-M448 PolarHBondContact OH-O 3.1Å; L362-M448 HydrophobicContact CD2-SD 4.31Å; Y418-M448 HydrophobicContact CD1-SD 4.38Å; D446-M448 PolarHBondContact O-N 3.09Å; D446-M448 VanDerWaalsContact O-N 3.12Å; D446-M448 WeakPolarHBondContact OD1-CB 3.28Å; D446-M448 PolarHBondContact OD1-N 3.12Å
449G91.5Very high92.2Very high11 Ų1134.2 Ų34.211%0.11321%0.213CC..G310 helixtrans-85.2-12.7174.500000115.2Q145 L288 D446 P447Q145-G449 PolarHBondContact NE2-O 3.05Å; L288-G449 VanDerWaalsContact CD1-O 3.29Å; L288-G449 WeakPolarHBondContact CD1-O 3.09Å; L288-G449 VanDerWaalsContact CD2-CA 3.44Å; D446-G449 PolarHBondContact O-N 3.03Å; P447-G449 PolarHBondContact O-N 3.23Å
450S84.6Confident91.7Very high39 Ų3935.6 Ų35.627%0.27322%0.219SC..  trans-81.5141.9-173.6178.90000113.2Q145 L368 M369 P447Q145-S450 PolarHBondContact NE2-O 3.25Å; L368-S450 WeakPolarHBondContact CD1-OG 3.37Å; M369-S450 WeakPolarHBondContact CB-O 3.49Å; M369-S450 WeakPolarHBondContact CE-O 3.42Å; M369-S450 CarbonylContact O-C 3.52Å; M369-S450 VanDerWaalsContact O-C 3.27Å; M369-S450 WeakPolarHBondContact O-CB 3.33Å; M369-S450 VanDerWaalsContact O-O 3.08Å; M369-S450 PolarHBondContact O-OG 2.91Å; P447-S450 PolarHBondContact O-N 3.44Å
451L79.9Confident91.1Very high4 Ų432.3 Ų32.32%0.02120%0.199CC..  trans-162.8117163.2-159.7159.6000109C72 W73 G143 G144 W322 M369 A372C72-L451 WeakPolarHBondContact SG-CD2 3.43Å; W73-L451 HydrophobicContact CB-CD1 4.37Å; W73-L451 HydrophobicContact CB-CD2 3.75Å; W73-L451 HydrophobicContact CG-CD2 4.3Å; G143-L451 CarbonylContact C-O 3.54Å; G143-L451 WeakPolarHBondContact CA-O 3.46Å; G144-L451 PolarHBondContact N-O 3.4Å; G144-L451 WeakPolarHBondContact O-CB 3.42Å; G144-L451 WeakPolarHBondContact O-CD1 3.43Å; W322-L451 HydrophobicContact CH2-CD1 3.48Å; W322-L451 VanDerWaalsContact CH2-CD1 3.48Å; W322-L451 HydrophobicContact CZ2-CD1 3.57Å; M369-L451 HydrophobicContact CE-CB 4.11Å; M369-L451 HydrophobicContact CE-CD1 3.86Å; M369-L451 HydrophobicContact CE-CG 4.26Å; M369-L451 HydrophobicContact CG-CB 4.42Å; M369-L451 HydrophobicContact CG-CD1 4.31Å; M369-L451 HydrophobicContact CG-CG 4.09Å; M369-L451 HydrophobicContact SD-CD1 3.87Å; M369-L451 HydrophobicContact SD-CG 4.3Å; A372-L451 HydrophobicContact CB-CD1 4.11Å; A372-L451 HydrophobicContact CB-CD2 4Å
452A51.9Low90.4Very high59 Ų5928.8 Ų28.849%0.48818%0.178SC..  trans69.80-178.400000117.4G70 C72 N141 T370G70-A452 WeakPolarHBondContact O-CB 3.48Å; C72-A452 VanDerWaalsContact SG-CB 3.55Å; N141-A452 PolarHBondContact ND2-O 3.29Å; N141-A452 PolarHBondContact OD1-O 3.14Å; T370-A452 WeakPolarHBondContact O-CA 3.39Å; T370-A452 PolarHBondContact O-N 3.29Å

Retrieved 452 of 452 residues in 183.6 ms (Link to these results)