A0A096MB22_POEFO Loading...

THO complex 1

AlphaFold DB , UniProt , Accession A0A096MB22, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 654 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M39.2Very low67.2Low242 Ų24296.9 Ų96.9100%1.19255%0.553SS**  0122.30-67.8-169.3-163.700107
2S36.7Very low68.8Low111 Ų11195.4 Ų95.478%0.77654%0.535SS*.PPolyproline II helixtrans-58.9142.2173.9-430000109.3
3P48.1Very low70.2Confident108 Ų10898.3 Ų98.370%0.70154%0.542SS*.PPolyproline II helixtrans-56.2142.617323.9-30.9000108.8V5P3-V5 PolarHBondContact O-N 2.87Å; P3-V5 VanDerWaalsContact O-N 3.13Å
4P57.9Low71.3Confident102 Ų102100.4 Ų100.466%0.66254%0.543SS*.PPolyproline II helixtrans-57.1123.5-178.324.2-31.8000108.7F6P4-F6 PolarHBondContact O-N 3.22Å
5V63.2Low72.3Confident136 Ų13693.7 Ų93.782%0.82451%0.507SS*.PPolyproline II helixtrans-65117.8178.9-179.70000107.5P3 N7P3-V5 PolarHBondContact O-N 2.87Å; P3-V5 VanDerWaalsContact O-N 3.13Å; V5-N7 PolarHBondContact O-N 3.02Å; V5-N7 VanDerWaalsContact O-N 3.08Å
6F76.8Confident73.2Confident35 Ų3589.3 Ų89.315%0.15448%0.484CS..  trans-69.8104177.3-175.7-98.5000109.2P4 F8 V11 I38 E44 K45 T48P4-F6 PolarHBondContact O-N 3.22Å; F6-F8 AromaticContact CD1-CD2 3.64Å; F6-F8 HydrophobicContact CD1-CD2 3.64Å; F6-F8 HydrophobicContact CD1-CE2 4.12Å; F6-F8 HydrophobicContact CD1-CG 4.46Å; F6-F8 AromaticContact CE1-CD2 3.52Å; F6-F8 HydrophobicContact CE1-CD2 3.52Å; F6-F8 AromaticContact CE1-CE2 3.78Å; F6-F8 HydrophobicContact CE1-CE2 3.78Å; F6-F8 HydrophobicContact CE1-CG 4.16Å; F6-F8 PolarHBondContact O-N 3.42Å; F6-V11 HydrophobicContact CD2-CG2 4.43Å; F6-V11 HydrophobicContact CE2-CB 4.36Å; F6-V11 HydrophobicContact CE2-CG1 4.01Å; F6-V11 HydrophobicContact CE2-CG2 3.94Å; F6-V11 HydrophobicContact CZ-CB 4.04Å; F6-V11 HydrophobicContact CZ-CG1 3.63Å; F6-V11 HydrophobicContact CZ-CG2 4.11Å; F6-I38 HydrophobicContact CE2-CG2 4.08Å; F6-E44 HydrophobicContact CD1-CB 4.21Å; F6-E44 HydrophobicContact CE1-CB 4Å; F6-E44 HydrophobicContact CZ-CB 4.27Å; F6-K45 HydrophobicContact CE2-CG 4.02Å; F6-K45 HydrophobicContact CZ-CG 4.39Å; F6-T48 HydrophobicContact CE1-CG2 3.68Å; F6-T48 HydrophobicContact CZ-CG2 3.92Å
7N82.3Confident73.9Confident73 Ų7387.5 Ų87.539%0.3948%0.484SS..  trans-79.799.2176.6-170.1-12.8000110.1V5 V9 D10 V11V5-N7 PolarHBondContact O-N 3.02Å; V5-N7 VanDerWaalsContact O-N 3.08Å; N7-V9 VanDerWaalsContact C-N 3.26Å; N7-V9 PolarHBondContact O-N 2.69Å; N7-V9 PolarHBondContact OD1-N 3.35Å; N7-D10 HydrophobicContact CB-CB 4.3Å; N7-D10 PolarHBondContact ND2-OD1 3.37Å; N7-D10 PolarHBondContact ND2-OD2 3.04Å; N7-V11 WeakPolarHBondContact O-CB 3.48Å; N7-V11 VanDerWaalsContact O-CG2 3.26Å; N7-V11 WeakPolarHBondContact O-CG2 3.36Å; N7-V11 PolarHBondContact O-N 3.04Å; N7-V11 VanDerWaalsContact O-N 3.12Å
8F82.7Confident74.5Confident79 Ų7982.8 Ų82.835%0.34646%0.458SS..Hα-helixtrans-56.3-36.6-176.7-129.7-93.6000113.2F6 K12 T48F6-F8 AromaticContact CD1-CD2 3.64Å; F6-F8 HydrophobicContact CD1-CD2 3.64Å; F6-F8 HydrophobicContact CD1-CE2 4.12Å; F6-F8 HydrophobicContact CD1-CG 4.46Å; F6-F8 AromaticContact CE1-CD2 3.52Å; F6-F8 HydrophobicContact CE1-CD2 3.52Å; F6-F8 AromaticContact CE1-CE2 3.78Å; F6-F8 HydrophobicContact CE1-CE2 3.78Å; F6-F8 HydrophobicContact CE1-CG 4.16Å; F6-F8 PolarHBondContact O-N 3.42Å; F8-K12 WeakPolarHBondContact O-CB 3.3Å; F8-K12 PolarHBondContact O-N 3.37Å; F8-T48 HydrophobicContact CD1-CG2 3.27Å; F8-T48 HydrophobicContact CD2-CG2 3.99Å; F8-T48 HydrophobicContact CE1-CG2 3.17Å; F8-T48 HydrophobicContact CE2-CG2 3.89Å; F8-T48 HydrophobicContact CG-CG2 3.69Å; F8-T48 HydrophobicContact CZ-CG2 3.49Å; F8-T48 VanDerWaalsContact CZ-CG2 3.49Å
9V84.4Confident74.9Confident87 Ų8778.4 Ų78.453%0.52743%0.434SS..Hα-helixtrans-74.1-51.7-174.8-178.40000110.6N7 V11 K12 E13N7-V9 VanDerWaalsContact C-N 3.26Å; N7-V9 PolarHBondContact O-N 2.69Å; N7-V9 PolarHBondContact OD1-N 3.35Å; V9-V11 VanDerWaalsContact C-N 3.27Å; V9-V11 PolarHBondContact O-N 3.3Å; V9-K12 PolarHBondContact O-N 3.45Å; V9-E13 PolarHBondContact O-N 3.33Å
10D84.5Confident75.4Confident80 Ų8081.1 Ų81.143%0.42844%0.437SS..Hα-helixtrans-61.4-38.6179.5-60-5000111.6N7 K14N7-D10 HydrophobicContact CB-CB 4.3Å; N7-D10 PolarHBondContact ND2-OD1 3.37Å; N7-D10 PolarHBondContact ND2-OD2 3.04Å; D10-K14 WeakPolarHBondContact O-CG 3.34Å; D10-K14 PolarHBondContact O-N 3.33Å
11V83.9Confident75.7Confident13 Ų1382.5 Ų82.58%0.07944%0.441CS..Hα-helixtrans-69.5-41.3178171.50000110.9F6 N7 V9 K14 F15 I38 T48F6-V11 HydrophobicContact CD2-CG2 4.43Å; F6-V11 HydrophobicContact CE2-CB 4.36Å; F6-V11 HydrophobicContact CE2-CG1 4.01Å; F6-V11 HydrophobicContact CE2-CG2 3.94Å; F6-V11 HydrophobicContact CZ-CB 4.04Å; F6-V11 HydrophobicContact CZ-CG1 3.63Å; F6-V11 HydrophobicContact CZ-CG2 4.11Å; N7-V11 WeakPolarHBondContact O-CB 3.48Å; N7-V11 VanDerWaalsContact O-CG2 3.26Å; N7-V11 WeakPolarHBondContact O-CG2 3.36Å; N7-V11 PolarHBondContact O-N 3.04Å; N7-V11 VanDerWaalsContact O-N 3.12Å; V9-V11 VanDerWaalsContact C-N 3.27Å; V9-V11 PolarHBondContact O-N 3.3Å; V11-K14 PolarHBondContact O-N 3.4Å; V11-F15 HydrophobicContact CG1-CD2 3.56Å; V11-F15 HydrophobicContact CG1-CE2 3.32Å; V11-F15 HydrophobicContact CG1-CZ 4.26Å; V11-F15 WeakPolarHBondContact O-CD2 3.35Å; V11-F15 PolarHBondContact O-N 3.35Å; V11-I38 HydrophobicContact CG1-CD1 4.09Å; V11-I38 HydrophobicContact CG1-CG2 4.19Å; V11-I38 HydrophobicContact CG2-CG2 4.08Å; V11-T48 HydrophobicContact CG1-CG2 4.33Å
12K85.7Confident77.6Confident79 Ų7971 Ų7134%0.34339%0.385SS..Hα-helixtrans-61.1-45.8175.2-177.9-177.6174.8-176.20111.4F8 V9 K14 F15 T16 A52F8-K12 WeakPolarHBondContact O-CB 3.3Å; F8-K12 PolarHBondContact O-N 3.37Å; V9-K12 PolarHBondContact O-N 3.45Å; K12-K14 VanDerWaalsContact C-N 3.33Å; K12-K14 PolarHBondContact O-N 2.82Å; K12-F15 PolarHBondContact O-N 3.42Å; K12-T16 WeakPolarHBondContact O-CB 3.46Å; K12-T16 PolarHBondContact O-N 3.02Å; K12-T16 PolarHBondContact O-OG1 3.43Å; K12-A52 HydrophobicContact CG-CB 4.31Å
13E87.4Confident79.6Confident133 Ų13367 Ų6762%0.62136%0.355SS*.Hα-helixtrans-60.7-41.9178-73.3-173.117200112.3V9 T16 A17V9-E13 PolarHBondContact O-N 3.33Å; E13-T16 PolarHBondContact O-N 2.87Å; E13-A17 PolarHBondContact O-N 2.87Å
14K85.8Confident80.9Confident128 Ų12866.8 Ų66.856%0.55736%0.355SS*.Hα-helixtrans-62-44174.4-73.3173.7-176.5176.60112.1D10 V11 K12 A17 A18D10-K14 WeakPolarHBondContact O-CG 3.34Å; D10-K14 PolarHBondContact O-N 3.33Å; V11-K14 PolarHBondContact O-N 3.4Å; K12-K14 VanDerWaalsContact C-N 3.33Å; K12-K14 PolarHBondContact O-N 2.82Å; K14-A17 PolarHBondContact O-N 3.22Å; K14-A18 WeakPolarHBondContact O-CB 3.47Å; K14-A18 PolarHBondContact O-N 3.22Å
15F86.6Confident81.5Confident0 Ų064 Ų640%035%0.345CS..Hα-helixtrans-66.8-36.9175.6-76.6-45000112.8V11 K12 A18 A19 V34 F35 I38 L49 A52V11-F15 HydrophobicContact CG1-CD2 3.56Å; V11-F15 HydrophobicContact CG1-CE2 3.32Å; V11-F15 HydrophobicContact CG1-CZ 4.26Å; V11-F15 WeakPolarHBondContact O-CD2 3.35Å; V11-F15 PolarHBondContact O-N 3.35Å; K12-F15 PolarHBondContact O-N 3.42Å; F15-A18 PolarHBondContact O-N 2.95Å; F15-A19 VanDerWaalsContact O-CB 3.24Å; F15-A19 WeakPolarHBondContact O-CB 3.4Å; F15-A19 PolarHBondContact O-N 3.1Å; F15-V34 HydrophobicContact CD1-CG1 4.15Å; F15-V34 HydrophobicContact CE1-CG1 4.19Å; F15-F35 HydrophobicContact CE1-CB 4.14Å; F15-F35 HydrophobicContact CE1-CD2 4Å; F15-F35 AromaticContact CZ-CD2 3.74Å; F15-F35 HydrophobicContact CZ-CD2 3.74Å; F15-F35 HydrophobicContact CZ-CE2 4.49Å; F15-F35 HydrophobicContact CZ-CG 4.5Å; F15-I38 HydrophobicContact CD1-CD1 4.1Å; F15-I38 HydrophobicContact CD2-CD1 4.45Å; F15-I38 HydrophobicContact CE1-CD1 3.43Å; F15-I38 VanDerWaalsContact CE1-CD1 3.43Å; F15-I38 HydrophobicContact CE2-CD1 3.85Å; F15-I38 HydrophobicContact CZ-CD1 3.29Å; F15-L49 HydrophobicContact CB-CD1 3.99Å; F15-L49 HydrophobicContact CD1-CD1 3.91Å; F15-L49 HydrophobicContact CD2-CB 4.22Å; F15-L49 HydrophobicContact CE2-CB 4.3Å; F15-L49 HydrophobicContact CG-CB 4.41Å; F15-L49 HydrophobicContact CG-CD1 3.95Å; F15-A52 HydrophobicContact CB-CB 3.66Å
16T86Confident82Confident22 Ų2265.2 Ų65.214%0.13534%0.339CS..Hα-helixtrans-63.5-44.7175-63.80000111K12 E13 A19 R20 V56K12-T16 WeakPolarHBondContact O-CB 3.46Å; K12-T16 PolarHBondContact O-N 3.02Å; K12-T16 PolarHBondContact O-OG1 3.43Å; E13-T16 PolarHBondContact O-N 2.87Å; T16-A19 PolarHBondContact O-N 3.19Å; T16-R20 WeakPolarHBondContact O-CG 3.35Å; T16-R20 PolarHBondContact O-N 3.02Å; T16-V56 HydrophobicContact CG2-CG2 3.82Å
17A85.8Confident81.9Confident59 Ų5966.7 Ų66.749%0.48835%0.351SS..Hα-helixtrans-62-45.8174.800000111.6E13 K14 A19 R20 Q21E13-A17 PolarHBondContact O-N 2.87Å; K14-A17 PolarHBondContact O-N 3.22Å; A17-A19 VanDerWaalsContact C-N 3.34Å; A17-A19 PolarHBondContact O-N 3.24Å; A17-R20 PolarHBondContact O-N 3.04Å; A17-Q21 PolarHBondContact O-N 3.27Å
18A83.8Confident81.6Confident3 Ų363.8 Ų63.83%0.02534%0.336CS..Hα-helixtrans-63-38.6177.500000112.5K14 F15 Q21 A22 L31 V34K14-A18 WeakPolarHBondContact O-CB 3.47Å; K14-A18 PolarHBondContact O-N 3.22Å; F15-A18 PolarHBondContact O-N 2.95Å; A18-Q21 PolarHBondContact O-N 3.06Å; A18-A22 VanDerWaalsContact O-CB 3.23Å; A18-A22 WeakPolarHBondContact O-CB 3.32Å; A18-A22 PolarHBondContact O-N 3.43Å; A18-L31 HydrophobicContact CB-CD1 3.98Å; A18-V34 HydrophobicContact CB-CB 4.23Å; A18-V34 HydrophobicContact CB-CG1 4.22Å; A18-V34 HydrophobicContact CB-CG2 4.01Å
19A83.1Confident81.5Confident0 Ų067.7 Ų67.70%035%0.353CS..Hα-helixtrans-66.8-42.2176.600000112F15 T16 A17 Q21 A22 L23 L31 L53 V56F15-A19 VanDerWaalsContact O-CB 3.24Å; F15-A19 WeakPolarHBondContact O-CB 3.4Å; F15-A19 PolarHBondContact O-N 3.1Å; T16-A19 PolarHBondContact O-N 3.19Å; A17-A19 VanDerWaalsContact C-N 3.34Å; A17-A19 PolarHBondContact O-N 3.24Å; A19-Q21 VanDerWaalsContact C-N 3.33Å; A19-Q21 PolarHBondContact O-N 3.19Å; A19-A22 PolarHBondContact O-N 3.17Å; A19-L23 WeakPolarHBondContact O-CB 3.46Å; A19-L23 WeakPolarHBondContact O-CG 3.38Å; A19-L23 PolarHBondContact O-N 3.1Å; A19-L31 HydrophobicContact CB-CD1 4.39Å; A19-L53 HydrophobicContact CB-CD2 4Å; A19-V56 HydrophobicContact CB-CG2 4.13Å
20R83.8Confident81.2Confident132 Ų13266.8 Ų66.850%0.49834%0.343SS..Hα-helixtrans-62.8-40.1174-71.3179.8-178.3166.30.3111.8T16 A17 L23 S24 V56 D59T16-R20 WeakPolarHBondContact O-CG 3.35Å; T16-R20 PolarHBondContact O-N 3.02Å; A17-R20 PolarHBondContact O-N 3.04Å; R20-L23 WeakPolarHBondContact O-CB 3.18Å; R20-L23 PolarHBondContact O-N 3.12Å; R20-S24 PolarHBondContact O-N 3.05Å; R20-S24 VanDerWaalsContact O-N 3.16Å; R20-V56 HydrophobicContact CG-CG1 4.34Å; R20-V56 HydrophobicContact CG-CG2 4.13Å; R20-D59 IonicContact CZ-OD2 3.91Å; R20-D59 IonicContact NH2-OD2 3.11Å; R20-D59 PolarHBondContact NH2-OD2 3.05Å
21Q81.5Confident81.1Confident110 Ų11063 Ų6351%0.51432%0.323SS..Hα-helixtrans-68.1-41.2175.6-1691693.900111.7A17 A18 A19 L23 S24 G25 H30A17-Q21 PolarHBondContact O-N 3.27Å; A18-Q21 PolarHBondContact O-N 3.06Å; A19-Q21 VanDerWaalsContact C-N 3.33Å; A19-Q21 PolarHBondContact O-N 3.19Å; Q21-L23 VanDerWaalsContact C-N 3.32Å; Q21-L23 PolarHBondContact O-N 3.02Å; Q21-S24 PolarHBondContact O-N 3.33Å; Q21-S24 PolarHBondContact O-OG 2.78Å; Q21-G25 PolarHBondContact O-N 3.13Å; Q21-H30 PolarHBondContact OE1-NE2 3.33Å; Q21-H30 VanDerWaalsContact OE1-NE2 3.1Å
22A79.1Confident81Confident1 Ų164.9 Ų64.91%0.00833%0.332CS..Hα-helixtrans-63.9-35.3176.300000112.6A18 A19 G25 K26 T27 L77A18-A22 VanDerWaalsContact O-CB 3.23Å; A18-A22 WeakPolarHBondContact O-CB 3.32Å; A18-A22 PolarHBondContact O-N 3.43Å; A19-A22 PolarHBondContact O-N 3.17Å; A22-G25 PolarHBondContact O-N 3.37Å; A22-K26 WeakPolarHBondContact O-CA 3.29Å; A22-K26 PolarHBondContact O-N 2.98Å; A22-T27 WeakPolarHBondContact CB-O 3.19Å; A22-T27 PolarHBondContact O-N 3.46Å; A22-L77 HydrophobicContact CB-CD1 4.01Å; A22-L77 HydrophobicContact CB-CD2 3.87Å
23L78.8Confident80.8Confident28 Ų2864.3 Ų64.315%0.14734%0.335CS..Hα-helixtrans-62.2-47.6171.3-81.8165.7000112A19 R20 Q21 G25 K26 V56 L74 L77A19-L23 WeakPolarHBondContact O-CB 3.46Å; A19-L23 WeakPolarHBondContact O-CG 3.38Å; A19-L23 PolarHBondContact O-N 3.1Å; R20-L23 WeakPolarHBondContact O-CB 3.18Å; R20-L23 PolarHBondContact O-N 3.12Å; Q21-L23 VanDerWaalsContact C-N 3.32Å; Q21-L23 PolarHBondContact O-N 3.02Å; L23-G25 VanDerWaalsContact C-N 3.28Å; L23-G25 PolarHBondContact O-N 2.98Å; L23-K26 PolarHBondContact O-N 3.27Å; L23-V56 HydrophobicContact CD1-CG1 3.53Å; L23-L74 HydrophobicContact CD1-CD1 4.1Å; L23-L74 HydrophobicContact CD2-CB 3.83Å; L23-L74 HydrophobicContact CD2-CD1 4Å; L23-L74 HydrophobicContact CD2-CG 4.48Å; L23-L74 HydrophobicContact CG-CD1 4.22Å; L23-L77 HydrophobicContact CG-CD2 4.35Å
24S75.8Confident80.6Confident102 Ų10259 Ų5971%0.71331%0.312SS*.Hα-helixtrans-63.8-34.4178.371.70000112.9R20 Q21R20-S24 PolarHBondContact O-N 3.05Å; R20-S24 VanDerWaalsContact O-N 3.16Å; Q21-S24 PolarHBondContact O-N 3.33Å; Q21-S24 PolarHBondContact O-OG 2.78Å
25G70.1Confident80.4Confident43 Ų4354 Ų5444%0.44329%0.29SS..Hα-helixtrans-89.5-7.6179.300000114.9Q21 A22 L23 T27Q21-G25 PolarHBondContact O-N 3.13Å; A22-G25 PolarHBondContact O-N 3.37Å; L23-G25 VanDerWaalsContact C-N 3.28Å; L23-G25 PolarHBondContact O-N 2.98Å; G25-T27 WeakPolarHBondContact O-CG2 3.48Å; G25-T27 PolarHBondContact O-N 3.34Å; G25-T27 VanDerWaalsContact O-N 3.16Å
26K73.4Confident80.2Confident163 Ų16358.1 Ų58.171%0.70932%0.319SS*.THydrogen-bonded Turntrans46.836.2-171.1-61.8-174.9176.8-1760113.9A22 L23A22-K26 WeakPolarHBondContact O-CA 3.29Å; A22-K26 PolarHBondContact O-N 2.98Å; L23-K26 PolarHBondContact O-N 3.27Å
27T74.6Confident80.1Confident66 Ų6664 Ų6441%0.40535%0.345SS..  trans-139.2135.9179.962.10000112.2A22 G25 K29A22-T27 WeakPolarHBondContact CB-O 3.19Å; A22-T27 PolarHBondContact O-N 3.46Å; G25-T27 WeakPolarHBondContact O-CG2 3.48Å; G25-T27 PolarHBondContact O-N 3.34Å; G25-T27 VanDerWaalsContact O-N 3.16Å; T27-K29 VanDerWaalsContact C-N 3.3Å; T27-K29 PolarHBondContact O-N 3.47Å
28C77.1Confident79.9Confident11 Ų1162.2 Ų62.27%0.07433%0.327CS..THydrogen-bonded Turntrans-72.5-17.9174.4-80.50000114.1H30 L31 I32 L77 D80C28-H30 VanDerWaalsContact C-N 3.26Å; C28-H30 PolarHBondContact O-N 3.44Å; C28-H30 VanDerWaalsContact O-N 3.1Å; C28-L31 WeakPolarHBondContact O-CA 3.42Å; C28-L31 WeakPolarHBondContact O-CB 3.35Å; C28-L31 PolarHBondContact O-N 3.26Å; C28-I32 HydrophobicContact CB-CG1 4.47Å; C28-I32 WeakPolarHBondContact O-CG1 3.44Å; C28-I32 PolarHBondContact O-N 3.14Å; C28-L77 HydrophobicContact CB-CD1 4.44Å; C28-L77 WeakPolarHBondContact SG-CD1 3.33Å; C28-L77 PolarHBondContact SG-O 2.7Å; C28-L77 VanDerWaalsContact SG-O 3.32Å; C28-D80 HydrophobicContact CB-CB 4.45Å; C28-D80 WeakPolarHBondContact SG-CB 3.49Å
29K79.5Confident79.2Confident161 Ų16166.1 Ų66.170%0.735%0.354SS*.Hα-helixtrans-51.5-41.1-171.5-67.5-176.2179.3178.60114.1T27 I32 T33T27-K29 VanDerWaalsContact C-N 3.3Å; T27-K29 PolarHBondContact O-N 3.47Å; K29-I32 PolarHBondContact O-N 3.18Å; K29-T33 PolarHBondContact O-N 3.31Å; K29-T33 VanDerWaalsContact O-N 3.13Å; K29-T33 PolarHBondContact O-OG1 2.79Å
30H79.7Confident78.9Confident68 Ų6867.9 Ų67.932%0.31537%0.373SS..Hα-helixtrans-67-41.5178.4-172.768.8000111.5Q21 C28 I32 T33 V34Q21-H30 PolarHBondContact OE1-NE2 3.33Å; Q21-H30 VanDerWaalsContact OE1-NE2 3.1Å; C28-H30 VanDerWaalsContact C-N 3.26Å; C28-H30 PolarHBondContact O-N 3.44Å; C28-H30 VanDerWaalsContact O-N 3.1Å; H30-I32 VanDerWaalsContact C-N 3.35Å; H30-I32 PolarHBondContact O-N 3.07Å; H30-T33 PolarHBondContact O-N 2.93Å; H30-V34 WeakPolarHBondContact O-CG2 3.3Å; H30-V34 PolarHBondContact O-N 3.39Å
31L81.3Confident78.8Confident0 Ų065.9 Ų65.90%037%0.372CS..Hα-helixtrans-61.6-41.3175.8-158.572.8000111.8A18 A19 C28 T33 V34 F35 L49 A81A18-L31 HydrophobicContact CB-CD1 3.98Å; A19-L31 HydrophobicContact CB-CD1 4.39Å; C28-L31 WeakPolarHBondContact O-CA 3.42Å; C28-L31 WeakPolarHBondContact O-CB 3.35Å; C28-L31 PolarHBondContact O-N 3.26Å; L31-T33 VanDerWaalsContact C-N 3.34Å; L31-T33 PolarHBondContact O-N 2.78Å; L31-V34 PolarHBondContact O-N 3.01Å; L31-F35 WeakPolarHBondContact O-CB 3.28Å; L31-F35 PolarHBondContact O-N 2.85Å; L31-L49 HydrophobicContact CD1-CD1 3.89Å; L31-L49 HydrophobicContact CD2-CD1 4.17Å; L31-L49 HydrophobicContact CD2-CD2 4.2Å; L31-L49 HydrophobicContact CG-CD1 4.22Å; L31-L49 HydrophobicContact CG-CD2 4.46Å; L31-A81 HydrophobicContact CD2-CB 4.23Å
32I82.2Confident78.8Confident53 Ų5366.4 Ų66.427%0.27237%0.374SS..Hα-helixtrans-61-45176-41.7-160.9000111.2C28 K29 H30 V34 F35 S36 E84 I86C28-I32 HydrophobicContact CB-CG1 4.47Å; C28-I32 WeakPolarHBondContact O-CG1 3.44Å; C28-I32 PolarHBondContact O-N 3.14Å; K29-I32 PolarHBondContact O-N 3.18Å; H30-I32 VanDerWaalsContact C-N 3.35Å; H30-I32 PolarHBondContact O-N 3.07Å; I32-V34 VanDerWaalsContact C-N 3.34Å; I32-V34 PolarHBondContact O-N 3.02Å; I32-F35 PolarHBondContact O-N 3.08Å; I32-S36 PolarHBondContact O-N 2.8Å; I32-S36 PolarHBondContact O-OG 2.98Å; I32-E84 HydrophobicContact CD1-CB 4.11Å; I32-E84 HydrophobicContact CD1-CG 3.82Å; I32-I86 HydrophobicContact CB-CD1 3.75Å; I32-I86 HydrophobicContact CD1-CD1 3.79Å; I32-I86 HydrophobicContact CG1-CD1 3.34Å; I32-I86 HydrophobicContact CG2-CD1 3.78Å
33T82.3Confident79Confident68 Ų6870.7 Ų70.742%0.41740%0.4SS..Hα-helixtrans-64.1-42-178.3-53.50000111K29 H30 L31 S36 Q37K29-T33 PolarHBondContact O-N 3.31Å; K29-T33 VanDerWaalsContact O-N 3.13Å; K29-T33 PolarHBondContact O-OG1 2.79Å; H30-T33 PolarHBondContact O-N 2.93Å; L31-T33 VanDerWaalsContact C-N 3.34Å; L31-T33 PolarHBondContact O-N 2.78Å; T33-S36 PolarHBondContact O-OG 2.86Å; T33-Q37 VanDerWaalsContact O-CG 3.22Å; T33-Q37 WeakPolarHBondContact O-CG 3.22Å; T33-Q37 PolarHBondContact O-N 3.19Å
34V81.4Confident79.3Confident21 Ų2173.1 Ų73.113%0.12741%0.411CS..Hα-helixtrans-69.3-38.9177.4175.20000111.1F15 A18 H30 L31 I32 S36 Q37 I38F15-V34 HydrophobicContact CD1-CG1 4.15Å; F15-V34 HydrophobicContact CE1-CG1 4.19Å; A18-V34 HydrophobicContact CB-CB 4.23Å; A18-V34 HydrophobicContact CB-CG1 4.22Å; A18-V34 HydrophobicContact CB-CG2 4.01Å; H30-V34 WeakPolarHBondContact O-CG2 3.3Å; H30-V34 PolarHBondContact O-N 3.39Å; L31-V34 PolarHBondContact O-N 3.01Å; I32-V34 VanDerWaalsContact C-N 3.34Å; I32-V34 PolarHBondContact O-N 3.02Å; V34-S36 PolarHBondContact O-N 3.29Å; V34-Q37 PolarHBondContact O-N 2.9Å; V34-I38 HydrophobicContact CG1-CD1 3.94Å; V34-I38 WeakPolarHBondContact O-CD1 3.45Å; V34-I38 WeakPolarHBondContact O-CG1 3.49Å; V34-I38 PolarHBondContact O-N 3.5Å
35F83.1Confident79.7Confident22 Ų2269.3 Ų69.310%0.09638%0.382CS..Hα-helixtrans-63.7-39.2178.2-173.5-90.5000113.2F15 L31 I32 K45 K46 L49 I86F15-F35 HydrophobicContact CE1-CB 4.14Å; F15-F35 HydrophobicContact CE1-CD2 4Å; F15-F35 AromaticContact CZ-CD2 3.74Å; F15-F35 HydrophobicContact CZ-CD2 3.74Å; F15-F35 HydrophobicContact CZ-CE2 4.49Å; F15-F35 HydrophobicContact CZ-CG 4.5Å; L31-F35 WeakPolarHBondContact O-CB 3.28Å; L31-F35 PolarHBondContact O-N 2.85Å; I32-F35 PolarHBondContact O-N 3.08Å; F35-K45 HydrophobicContact CD2-CB 4.21Å; F35-K45 HydrophobicContact CE1-CD 4.48Å; F35-K45 HydrophobicContact CE2-CB 3.46Å; F35-K45 VanDerWaalsContact CE2-CB 3.46Å; F35-K45 HydrophobicContact CE2-CD 4.45Å; F35-K45 HydrophobicContact CZ-CB 3.75Å; F35-K45 HydrophobicContact CZ-CD 4.23Å; F35-K46 HydrophobicContact CE2-CG 4.36Å; F35-K46 HydrophobicContact CZ-CG 4.14Å; F35-L49 HydrophobicContact CD2-CD2 4.12Å; F35-L49 HydrophobicContact CE2-CD2 4.48Å; F35-I86 HydrophobicContact CB-CG2 3.75Å; F35-I86 HydrophobicContact CD1-CG2 3.81Å; F35-I86 HydrophobicContact CD2-CG2 3.34Å; F35-I86 HydrophobicContact CE1-CG2 4.19Å; F35-I86 HydrophobicContact CE2-CG2 3.74Å; F35-I86 WeakPolarHBondContact CE2-O 3.47Å; F35-I86 HydrophobicContact CG-CG2 3.37Å; F35-I86 HydrophobicContact CZ-CG2 4.15Å
36S81.9Confident80.5Confident87 Ų8770 Ų7061%0.60837%0.372SS*.Hα-helixtrans-72.8-28.5177.964.20000113.2I32 T33 V34I32-S36 PolarHBondContact O-N 2.8Å; I32-S36 PolarHBondContact O-OG 2.98Å; T33-S36 PolarHBondContact O-OG 2.86Å; V34-S36 PolarHBondContact O-N 3.29Å
37Q83.3Confident81.1Confident145 Ų14565.1 Ų65.168%0.67836%0.356SS*.Hα-helixtrans-75.9-25.1179-75.4174.30.500113.9T33 V34T33-Q37 VanDerWaalsContact O-CG 3.22Å; T33-Q37 WeakPolarHBondContact O-CG 3.22Å; T33-Q37 PolarHBondContact O-N 3.19Å; V34-Q37 PolarHBondContact O-N 2.9Å
38I81.6Confident81.8Confident22 Ų2262 Ų6211%0.11334%0.337CS..SBendtrans-76.5134.2-179.8-67.8158.9000109.1F6 V11 F15 V34 K45F6-I38 HydrophobicContact CE2-CG2 4.08Å; V11-I38 HydrophobicContact CG1-CD1 4.09Å; V11-I38 HydrophobicContact CG1-CG2 4.19Å; V11-I38 HydrophobicContact CG2-CG2 4.08Å; F15-I38 HydrophobicContact CD1-CD1 4.1Å; F15-I38 HydrophobicContact CD2-CD1 4.45Å; F15-I38 HydrophobicContact CE1-CD1 3.43Å; F15-I38 VanDerWaalsContact CE1-CD1 3.43Å; F15-I38 HydrophobicContact CE2-CD1 3.85Å; F15-I38 HydrophobicContact CZ-CD1 3.29Å; V34-I38 HydrophobicContact CG1-CD1 3.94Å; V34-I38 WeakPolarHBondContact O-CD1 3.45Å; V34-I38 WeakPolarHBondContact O-CG1 3.49Å; V34-I38 PolarHBondContact O-N 3.5Å; I38-K45 HydrophobicContact CG2-CG 4.44Å; I38-K45 WeakPolarHBondContact O-CE 3.5Å; I38-K45 PolarHBondContact O-NZ 2.88Å
39S70.5Confident82.3Confident85 Ų8561.4 Ų61.459%0.59433%0.333SS*.  trans-88.7140172.339.60000110.5
40G75.7Confident82.7Confident38 Ų3854.8 Ų54.839%0.39231%0.305SS..SBendtrans147.3172.3-178.300000113.4K45G40-K45 WeakPolarHBondContact O-CE 3.43Å; G40-K45 PolarHBondContact O-NZ 3.45Å
41N82.5Confident83.2Confident90 Ų9056 Ų5648%0.48131%0.311SS..  trans-64.7137.5176.4-172.711.4000110.6T43 E44 K45N41-T43 VanDerWaalsContact C-N 3.27Å; N41-T43 PolarHBondContact O-N 3.35Å; N41-E44 HydrophobicContact CB-CB 4.31Å; N41-E44 HydrophobicContact CB-CG 4.07Å; N41-E44 WeakPolarHBondContact CB-OE2 3.37Å; N41-E44 PolarHBondContact O-N 3.11Å; N41-K45 WeakPolarHBondContact O-CG 3.45Å; N41-K45 PolarHBondContact O-N 3.08Å; N41-K45 VanDerWaalsContact O-N 3.08Å
42E81.4Confident83.6Confident120 Ų12056 Ų5656%0.56131%0.311SS*.Hα-helixtrans-59.5-38.4-177.8-75.2-164.7162.500112.4E44 K45 K46E42-E44 VanDerWaalsContact C-N 3.34Å; E42-E44 PolarHBondContact O-N 3.07Å; E42-K45 PolarHBondContact O-N 3.36Å; E42-K46 WeakPolarHBondContact O-CB 3.26Å; E42-K46 VanDerWaalsContact O-CG 3.26Å; E42-K46 WeakPolarHBondContact O-CG 3.22Å; E42-K46 PolarHBondContact O-N 3.31Å
43T83.4Confident83.9Confident91 Ų9153.5 Ų53.556%0.55830%0.298SS*.Hα-helixtrans-65-38-179.9-34.70000112.1N41 T47N41-T43 VanDerWaalsContact C-N 3.27Å; N41-T43 PolarHBondContact O-N 3.35Å; T43-T47 WeakPolarHBondContact O-CB 3.37Å; T43-T47 WeakPolarHBondContact O-CG2 3.45Å; T43-T47 PolarHBondContact O-N 3.24Å; T43-T47 PolarHBondContact O-OG1 3.41Å
44E84.1Confident84.3Confident79 Ų7956.2 Ų56.237%0.36930%0.301SS..Hα-helixtrans-70.7-38.9177.5-67.1174.1163.200111.2F6 N41 E42 T47 T48F6-E44 HydrophobicContact CD1-CB 4.21Å; F6-E44 HydrophobicContact CE1-CB 4Å; F6-E44 HydrophobicContact CZ-CB 4.27Å; N41-E44 HydrophobicContact CB-CB 4.31Å; N41-E44 HydrophobicContact CB-CG 4.07Å; N41-E44 WeakPolarHBondContact CB-OE2 3.37Å; N41-E44 PolarHBondContact O-N 3.11Å; E42-E44 VanDerWaalsContact C-N 3.34Å; E42-E44 PolarHBondContact O-N 3.07Å; E44-T47 WeakPolarHBondContact CA-OG1 3.49Å; E44-T47 PolarHBondContact O-OG1 3.31Å; E44-T48 WeakPolarHBondContact O-CB 3.37Å; E44-T48 PolarHBondContact O-N 3.21Å; E44-T48 PolarHBondContact O-OG1 2.88Å
45K85.1Confident84.7Confident23 Ų2356.6 Ų56.610%0.131%0.309CS..Hα-helixtrans-64.2-43.8173.6-67.1172177.21760112.3F6 F35 I38 G40 N41 E42 T48 L49F6-K45 HydrophobicContact CE2-CG 4.02Å; F6-K45 HydrophobicContact CZ-CG 4.39Å; F35-K45 HydrophobicContact CD2-CB 4.21Å; F35-K45 HydrophobicContact CE1-CD 4.48Å; F35-K45 HydrophobicContact CE2-CB 3.46Å; F35-K45 VanDerWaalsContact CE2-CB 3.46Å; F35-K45 HydrophobicContact CE2-CD 4.45Å; F35-K45 HydrophobicContact CZ-CB 3.75Å; F35-K45 HydrophobicContact CZ-CD 4.23Å; I38-K45 HydrophobicContact CG2-CG 4.44Å; I38-K45 WeakPolarHBondContact O-CE 3.5Å; I38-K45 PolarHBondContact O-NZ 2.88Å; G40-K45 WeakPolarHBondContact O-CE 3.43Å; G40-K45 PolarHBondContact O-NZ 3.45Å; N41-K45 WeakPolarHBondContact O-CG 3.45Å; N41-K45 PolarHBondContact O-N 3.08Å; N41-K45 VanDerWaalsContact O-N 3.08Å; E42-K45 PolarHBondContact O-N 3.36Å; K45-T48 VanDerWaalsContact CA-OG1 3.25Å; K45-T48 WeakPolarHBondContact CA-OG1 3.33Å; K45-T48 PolarHBondContact O-N 2.99Å; K45-T48 PolarHBondContact O-OG1 2.88Å; K45-L49 VanDerWaalsContact O-CB 3.31Å; K45-L49 WeakPolarHBondContact O-CB 3.31Å; K45-L49 PolarHBondContact O-N 3.06Å
46K86.7Confident84.9Confident57 Ų5755.7 Ų55.725%0.24831%0.305CS..Hα-helixtrans-61-48.7177.5-75.1179.1178.8-173.50110.9F35 E42 L49 D50 G85 I86F35-K46 HydrophobicContact CE2-CG 4.36Å; F35-K46 HydrophobicContact CZ-CG 4.14Å; E42-K46 WeakPolarHBondContact O-CB 3.26Å; E42-K46 VanDerWaalsContact O-CG 3.26Å; E42-K46 WeakPolarHBondContact O-CG 3.22Å; E42-K46 PolarHBondContact O-N 3.31Å; K46-L49 PolarHBondContact O-N 3.11Å; K46-D50 WeakPolarHBondContact O-CB 3.41Å; K46-D50 PolarHBondContact O-N 3.47Å; K46-G85 WeakPolarHBondContact CE-O 3.43Å; K46-G85 PolarHBondContact NZ-O 2.86Å; K46-I86 WeakPolarHBondContact CG-O 3.21Å
47T86.6Confident85.1Confident60 Ų6051.7 Ų51.737%0.36828%0.277SS..Hα-helixtrans-67.9-37-18049.40000113.4T43 E44 Q51T43-T47 WeakPolarHBondContact O-CB 3.37Å; T43-T47 WeakPolarHBondContact O-CG2 3.45Å; T43-T47 PolarHBondContact O-N 3.24Å; T43-T47 PolarHBondContact O-OG1 3.41Å; E44-T47 WeakPolarHBondContact CA-OG1 3.49Å; E44-T47 PolarHBondContact O-OG1 3.31Å; T47-Q51 WeakPolarHBondContact O-CG 3.24Å; T47-Q51 PolarHBondContact O-N 3.44Å
48T88.3Confident85.2Confident0 Ų046 Ų460%026%0.258CS..Hα-helixtrans-63.3-42.9171.430.40000111.9F6 F8 V11 E44 K45 Q51 A52F6-T48 HydrophobicContact CE1-CG2 3.68Å; F6-T48 HydrophobicContact CZ-CG2 3.92Å; F8-T48 HydrophobicContact CD1-CG2 3.27Å; F8-T48 HydrophobicContact CD2-CG2 3.99Å; F8-T48 HydrophobicContact CE1-CG2 3.17Å; F8-T48 HydrophobicContact CE2-CG2 3.89Å; F8-T48 HydrophobicContact CG-CG2 3.69Å; F8-T48 HydrophobicContact CZ-CG2 3.49Å; F8-T48 VanDerWaalsContact CZ-CG2 3.49Å; V11-T48 HydrophobicContact CG1-CG2 4.33Å; E44-T48 WeakPolarHBondContact O-CB 3.37Å; E44-T48 PolarHBondContact O-N 3.21Å; E44-T48 PolarHBondContact O-OG1 2.88Å; K45-T48 VanDerWaalsContact CA-OG1 3.25Å; K45-T48 WeakPolarHBondContact CA-OG1 3.33Å; K45-T48 PolarHBondContact O-N 2.99Å; K45-T48 PolarHBondContact O-OG1 2.88Å; T48-Q51 PolarHBondContact O-N 3.49Å; T48-A52 WeakPolarHBondContact O-CB 3.35Å; T48-A52 PolarHBondContact O-N 3.17Å
49L87.7Confident85.5Confident0 Ų047.9 Ų47.90%027%0.268CS..Hα-helixtrans-65.1-42.8177.5179.858.4000111.8F15 L31 F35 K45 K46 Q51 A52 L53 I86 C87F15-L49 HydrophobicContact CB-CD1 3.99Å; F15-L49 HydrophobicContact CD1-CD1 3.91Å; F15-L49 HydrophobicContact CD2-CB 4.22Å; F15-L49 HydrophobicContact CE2-CB 4.3Å; F15-L49 HydrophobicContact CG-CB 4.41Å; F15-L49 HydrophobicContact CG-CD1 3.95Å; L31-L49 HydrophobicContact CD1-CD1 3.89Å; L31-L49 HydrophobicContact CD2-CD1 4.17Å; L31-L49 HydrophobicContact CD2-CD2 4.2Å; L31-L49 HydrophobicContact CG-CD1 4.22Å; L31-L49 HydrophobicContact CG-CD2 4.46Å; F35-L49 HydrophobicContact CD2-CD2 4.12Å; F35-L49 HydrophobicContact CE2-CD2 4.48Å; K45-L49 VanDerWaalsContact O-CB 3.31Å; K45-L49 WeakPolarHBondContact O-CB 3.31Å; K45-L49 PolarHBondContact O-N 3.06Å; K46-L49 PolarHBondContact O-N 3.11Å; L49-Q51 VanDerWaalsContact C-N 3.3Å; L49-Q51 PolarHBondContact O-N 3Å; L49-A52 WeakPolarHBondContact O-CB 3.4Å; L49-A52 PolarHBondContact O-N 3.2Å; L49-A52 VanDerWaalsContact O-N 3.11Å; L49-L53 HydrophobicContact CD1-CG 4.37Å; L49-L53 HydrophobicContact CG-CD1 4.42Å; L49-L53 WeakPolarHBondContact O-CG 3.47Å; L49-L53 PolarHBondContact O-N 3.5Å; L49-I86 HydrophobicContact CD2-CG2 3.59Å; L49-C87 WeakPolarHBondContact CD2-SG 3.2Å
50D89.1Confident86Confident21 Ų2145.1 Ų45.111%0.11225%0.246CC..Hα-helixtrans-56.6-44.8174.2-70.7-16.3000111K46 R54 S88 I91K46-D50 WeakPolarHBondContact O-CB 3.41Å; K46-D50 PolarHBondContact O-N 3.47Å; D50-R54 PolarHBondContact O-N 3.34Å; D50-R54 VanDerWaalsContact O-N 3.07Å; D50-S88 PolarHBondContact OD1-N 3.31Å; D50-S88 WeakPolarHBondContact OD2-CB 3.29Å; D50-I91 HydrophobicContact CB-CD1 3.87Å; D50-I91 HydrophobicContact CB-CG1 4.16Å
51Q89.1Confident86.4Confident94 Ų9444.9 Ų44.944%0.43924%0.235SC..Hα-helixtrans-67.6-35.2175.5-72.7-175.16.500113.2T47 T48 L49 G55T47-Q51 WeakPolarHBondContact O-CG 3.24Å; T47-Q51 PolarHBondContact O-N 3.44Å; T48-Q51 PolarHBondContact O-N 3.49Å; L49-Q51 VanDerWaalsContact C-N 3.3Å; L49-Q51 PolarHBondContact O-N 3Å; Q51-G55 PolarHBondContact O-N 3.21Å
52A89.9Confident86.4Confident0 Ų047 Ų470%025%0.245CC..Hα-helixtrans-65.8-44.7176.700000111.1K12 F15 T48 L49 G55 V56K12-A52 HydrophobicContact CG-CB 4.31Å; F15-A52 HydrophobicContact CB-CB 3.66Å; T48-A52 WeakPolarHBondContact O-CB 3.35Å; T48-A52 PolarHBondContact O-N 3.17Å; L49-A52 WeakPolarHBondContact O-CB 3.4Å; L49-A52 PolarHBondContact O-N 3.2Å; L49-A52 VanDerWaalsContact O-N 3.11Å; A52-G55 PolarHBondContact O-N 3.34Å; A52-V56 WeakPolarHBondContact O-CG2 3.48Å; A52-V56 PolarHBondContact O-N 3.42Å
53L88.9Confident86.2Confident1 Ų147.3 Ų47.31%0.00525%0.246CC..Hα-helixtrans-61.3-43.5175.4-69.9172.1000111.7A19 L49 G55 V56 L57 L74 I91 L95A19-L53 HydrophobicContact CB-CD2 4Å; L49-L53 HydrophobicContact CD1-CG 4.37Å; L49-L53 HydrophobicContact CG-CD1 4.42Å; L49-L53 WeakPolarHBondContact O-CG 3.47Å; L49-L53 PolarHBondContact O-N 3.5Å; L53-G55 VanDerWaalsContact C-N 3.33Å; L53-G55 PolarHBondContact O-N 3.5Å; L53-V56 PolarHBondContact O-N 2.76Å; L53-L57 PolarHBondContact O-N 3.03Å; L53-L74 HydrophobicContact CD2-CD1 3.9Å; L53-I91 HydrophobicContact CD1-CG1 4.45Å; L53-L95 HydrophobicContact CB-CD1 4.36Å
54R90.4Very high85.2Confident125 Ų12551.2 Ų51.247%0.47226%0.258SS..Hα-helixtrans-64.7-36.7175.8-161-179.6-168.1-171.23.5112.5D50 L57 G58 L95 D98D50-R54 PolarHBondContact O-N 3.34Å; D50-R54 VanDerWaalsContact O-N 3.07Å; R54-L57 PolarHBondContact O-N 3.14Å; R54-G58 PolarHBondContact O-N 3.5Å; R54-L95 HydrophobicContact CB-CD2 4.08Å; R54-L95 HydrophobicContact CG-CD2 4.23Å; R54-D98 IonicContact CZ-OD1 2.89Å; R54-D98 IonicContact CZ-OD2 3.34Å; R54-D98 VanDerWaalsContact CZ-OD2 3.28Å; R54-D98 IonicContact NE-OD1 2.71Å; R54-D98 IonicContact NE-OD2 2.59Å; R54-D98 PolarHBondContact NE-OD2 3.26Å; R54-D98 VanDerWaalsContact NH2-CG 3.34Å; R54-D98 IonicContact NH2-OD1 3.81Å; R54-D98 PolarHBondContact NH2-OD1 3.37Å; R54-D98 IonicContact NH2-OD2 3.65Å; R54-D98 PolarHBondContact NH2-OD2 3.47Å; R54-D98 VanDerWaalsContact NH2-OD2 3.08Å
55G88.9Confident83.7Confident28 Ų2856.5 Ų56.529%0.28928%0.28SS..Hα-helixtrans-63.3-46.1173.700000112.5Q51 A52 L53 L57 G58 D59Q51-G55 PolarHBondContact O-N 3.21Å; A52-G55 PolarHBondContact O-N 3.34Å; L53-G55 VanDerWaalsContact C-N 3.33Å; L53-G55 PolarHBondContact O-N 3.5Å; G55-L57 VanDerWaalsContact C-N 3.3Å; G55-L57 PolarHBondContact O-N 3.15Å; G55-G58 PolarHBondContact O-N 3.38Å; G55-G58 VanDerWaalsContact O-N 3.14Å; G55-D59 PolarHBondContact O-N 2.99Å
56V87.1Confident82.2Confident3 Ų357.2 Ų57.22%0.01829%0.286CS..Hα-helixtrans-60.5-41.1175.4174.30000111.3T16 A19 R20 L23 A52 L53 D59 Q60 L74T16-V56 HydrophobicContact CG2-CG2 3.82Å; A19-V56 HydrophobicContact CB-CG2 4.13Å; R20-V56 HydrophobicContact CG-CG1 4.34Å; R20-V56 HydrophobicContact CG-CG2 4.13Å; L23-V56 HydrophobicContact CD1-CG1 3.53Å; A52-V56 WeakPolarHBondContact O-CG2 3.48Å; A52-V56 PolarHBondContact O-N 3.42Å; L53-V56 PolarHBondContact O-N 2.76Å; V56-D59 PolarHBondContact O-N 3.22Å; V56-Q60 WeakPolarHBondContact O-CG 3.44Å; V56-Q60 PolarHBondContact O-N 2.99Å; V56-Q60 VanDerWaalsContact O-N 3.07Å; V56-L74 HydrophobicContact CG1-CD2 4.39Å
57L87.1Confident81.3Confident3 Ų357.2 Ų57.22%0.01629%0.294CS..Hα-helixtrans-61.7-45.6174.3-179.667.3000111.6L53 R54 G55 D59 Q60 I61 Y71 L74 L95 D98 V99L53-L57 PolarHBondContact O-N 3.03Å; R54-L57 PolarHBondContact O-N 3.14Å; G55-L57 VanDerWaalsContact C-N 3.3Å; G55-L57 PolarHBondContact O-N 3.15Å; L57-D59 VanDerWaalsContact C-N 3.34Å; L57-D59 PolarHBondContact O-N 3.34Å; L57-Q60 WeakPolarHBondContact O-CB 3.16Å; L57-Q60 PolarHBondContact O-N 2.92Å; L57-Q60 VanDerWaalsContact O-N 3.16Å; L57-I61 HydrophobicContact CD1-CD1 4.18Å; L57-I61 HydrophobicContact CD1-CG1 4.38Å; L57-I61 HydrophobicContact CD2-CD1 4.32Å; L57-I61 HydrophobicContact CG-CD1 3.85Å; L57-I61 HydrophobicContact CG-CG1 4.42Å; L57-I61 WeakPolarHBondContact O-CG1 3.33Å; L57-I61 PolarHBondContact O-N 3.45Å; L57-Y71 HydrophobicContact CD1-CD1 3.81Å; L57-Y71 HydrophobicContact CD1-CE1 4.47Å; L57-L74 HydrophobicContact CB-CD2 3.65Å; L57-L74 HydrophobicContact CD1-CD2 3.94Å; L57-L74 HydrophobicContact CG-CD2 4.38Å; L57-L95 HydrophobicContact CB-CD2 4.16Å; L57-L95 HydrophobicContact CD2-CB 4.12Å; L57-L95 HydrophobicContact CD2-CD2 3.65Å; L57-L95 HydrophobicContact CD2-CG 4.48Å; L57-D98 HydrophobicContact CD2-CB 4.12Å; L57-V99 HydrophobicContact CD1-CG2 3.5Å; L57-V99 HydrophobicContact CD2-CG2 3.76Å; L57-V99 HydrophobicContact CG-CG2 4.17Å
58G86.1Confident80.4Confident27 Ų2755.4 Ų55.428%0.27828%0.283SS..Hα-helixtrans-57.4-45.6177.700000112.3R54 G55 Q60 I61 I62R54-G58 PolarHBondContact O-N 3.5Å; G55-G58 PolarHBondContact O-N 3.38Å; G55-G58 VanDerWaalsContact O-N 3.14Å; G58-Q60 VanDerWaalsContact C-N 3.35Å; G58-Q60 PolarHBondContact O-N 3.48Å; G58-I61 PolarHBondContact O-N 2.9Å; G58-I62 VanDerWaalsContact O-CG1 3.27Å; G58-I62 WeakPolarHBondContact O-CG1 3.23Å; G58-I62 PolarHBondContact O-N 3.38Å
59D86.3Confident79.8Confident61 Ų6160.3 Ų60.333%0.32631%0.309SS..Hα-helixtrans-59.8-44.5175.3-63.7-20.9000111.2R20 G55 V56 L57 I61 I62 E63R20-D59 IonicContact CZ-OD2 3.91Å; R20-D59 IonicContact NH2-OD2 3.11Å; R20-D59 PolarHBondContact NH2-OD2 3.05Å; G55-D59 PolarHBondContact O-N 2.99Å; V56-D59 PolarHBondContact O-N 3.22Å; L57-D59 VanDerWaalsContact C-N 3.34Å; L57-D59 PolarHBondContact O-N 3.34Å; D59-I61 VanDerWaalsContact C-N 3.34Å; D59-I61 PolarHBondContact O-N 3.19Å; D59-I62 PolarHBondContact O-N 3.4Å; D59-E63 WeakPolarHBondContact O-CB 3.38Å; D59-E63 WeakPolarHBondContact O-CG 3.2Å; D59-E63 PolarHBondContact O-N 3.45Å
60Q82.1Confident79.4Confident27 Ų2763.5 Ų63.513%0.12633%0.326CS..Hα-helixtrans-63.4-36.7178.2-74.6-176.3-17.900113.4V56 L57 G58 T66 Y71V56-Q60 WeakPolarHBondContact O-CG 3.44Å; V56-Q60 PolarHBondContact O-N 2.99Å; V56-Q60 VanDerWaalsContact O-N 3.07Å; L57-Q60 WeakPolarHBondContact O-CB 3.16Å; L57-Q60 PolarHBondContact O-N 2.92Å; L57-Q60 VanDerWaalsContact O-N 3.16Å; G58-Q60 VanDerWaalsContact C-N 3.35Å; G58-Q60 PolarHBondContact O-N 3.48Å; Q60-T66 PolarHBondContact O-OG1 2.97Å; Q60-T66 VanDerWaalsContact O-OG1 3.11Å; Q60-Y71 HydrophobicContact CB-CD1 4.4Å; Q60-Y71 HydrophobicContact CB-CE1 3.87Å; Q60-Y71 PolarHBondContact O-OH 3Å
61I83.1Confident79Confident32 Ų3263 Ų6316%0.16432%0.323CS..Hα-helixtrans-70.2-43.6177.6-68170.1000110.2L57 G58 D59 Q64 Y71 C102L57-I61 HydrophobicContact CD1-CD1 4.18Å; L57-I61 HydrophobicContact CD1-CG1 4.38Å; L57-I61 HydrophobicContact CD2-CD1 4.32Å; L57-I61 HydrophobicContact CG-CD1 3.85Å; L57-I61 HydrophobicContact CG-CG1 4.42Å; L57-I61 WeakPolarHBondContact O-CG1 3.33Å; L57-I61 PolarHBondContact O-N 3.45Å; G58-I61 PolarHBondContact O-N 2.9Å; D59-I61 VanDerWaalsContact C-N 3.34Å; D59-I61 PolarHBondContact O-N 3.19Å; I61-Q64 WeakPolarHBondContact O-CG 3.4Å; I61-Q64 PolarHBondContact O-N 3.24Å; I61-Y71 HydrophobicContact CG1-CD1 4.48Å; I61-Y71 HydrophobicContact CG1-CE1 3.77Å; I61-C102 HydrophobicContact CD1-CB 4.12Å; I61-C102 HydrophobicContact CG2-CB 3.92Å
62I83.1Confident78.7Confident134 Ų13459.6 Ų59.669%0.68731%0.307SS*.Hα-helixtrans-67.3-41.3-179.1-68.1166.2000111.3G58 D59 Q64G58-I62 VanDerWaalsContact O-CG1 3.27Å; G58-I62 WeakPolarHBondContact O-CG1 3.23Å; G58-I62 PolarHBondContact O-N 3.38Å; D59-I62 PolarHBondContact O-N 3.4Å; I62-Q64 PolarHBondContact O-N 2.72Å; I62-Q64 VanDerWaalsContact O-N 3.14Å
63E76.8Confident78.4Confident127 Ų12760.9 Ų60.959%0.59332%0.317SS*.THydrogen-bonded Turntrans-67.5-12.3-178.9-73.7-178.2-178.600113D59 K65D59-E63 WeakPolarHBondContact O-CB 3.38Å; D59-E63 WeakPolarHBondContact O-CG 3.2Å; D59-E63 PolarHBondContact O-N 3.45Å; E63-K65 WeakPolarHBondContact O-CG 3.41Å; E63-K65 PolarHBondContact O-N 3.1Å
64Q63.1Low78.2Confident174 Ų17460.9 Ų60.981%0.81332%0.317SS*.  trans46.915.6176.2-72-169.6-6.500115.6I61 I62I61-Q64 WeakPolarHBondContact O-CG 3.4Å; I61-Q64 PolarHBondContact O-N 3.24Å; I62-Q64 PolarHBondContact O-N 2.72Å; I62-Q64 VanDerWaalsContact O-N 3.14Å
65K51.7Low78.1Confident190 Ų19055 Ų5583%0.82629%0.294SS*.  trans-97.7-3.2-171.1-89.3175.2179.5177.20113.9E63E63-K65 WeakPolarHBondContact O-CG 3.41Å; E63-K65 PolarHBondContact O-N 3.1Å
66T55Low78Confident38 Ų3858.5 Ų58.523%0.23330%0.3CS..  trans-109.9132-156.8-6.30000110.9Q60 D70Q60-T66 PolarHBondContact O-OG1 2.97Å; Q60-T66 VanDerWaalsContact O-OG1 3.11Å; T66-D70 HydrophobicContact CG2-CB 3.37Å; T66-D70 WeakPolarHBondContact CG2-OD2 3.47Å
67S66.9Low77.9Confident57 Ų5758.7 Ų58.740%0.39930%0.301SS..  trans-59.4156175.8173.90000109.8D69 D70S67-D69 PolarHBondContact O-N 3.45Å; S67-D69 PolarHBondContact OG-N 3.49Å; S67-D69 PolarHBondContact OG-OD2 3.41Å; S67-D69 VanDerWaalsContact OG-OD2 3.13Å; S67-D70 PolarHBondContact N-OD2 2.88Å; S67-D70 VanDerWaalsContact N-OD2 3.15Å; S67-D70 PolarHBondContact O-N 3.16Å
68C68.4Low77.9Confident21 Ų2158.6 Ų58.614%0.14230%0.3CS..Hα-helixtrans-48.2-33.1167.8-68.90000111.9D70 Y71 L72C68-D70 VanDerWaalsContact C-N 3.26Å; C68-D70 PolarHBondContact O-N 3.11Å; C68-Y71 PolarHBondContact O-N 3.14Å; C68-L72 VanDerWaalsContact O-CG 3.31Å; C68-L72 WeakPolarHBondContact O-CG 3.35Å; C68-L72 PolarHBondContact O-N 2.91Å; C68-L72 VanDerWaalsContact O-N 3.15Å
69D75.8Confident77.9Confident104 Ų10457.8 Ų57.856%0.55629%0.289SS*.Hα-helixtrans-64.2-28-178.2-59.4-38000113.7S67 S73S67-D69 PolarHBondContact O-N 3.45Å; S67-D69 PolarHBondContact OG-N 3.49Å; S67-D69 PolarHBondContact OG-OD2 3.41Å; S67-D69 VanDerWaalsContact OG-OD2 3.13Å; D69-S73 WeakPolarHBondContact O-CB 3.06Å; D69-S73 PolarHBondContact O-N 3.18Å; D69-S73 PolarHBondContact O-OG 2.76Å
70D77.6Confident77.8Confident66 Ų6658.5 Ų58.535%0.35329%0.293SS..Hα-helixtrans-77.6-39.3-177.8-63.3-53.8000111.1T66 S67 C68 L72 S73 L74T66-D70 HydrophobicContact CG2-CB 3.37Å; T66-D70 WeakPolarHBondContact CG2-OD2 3.47Å; S67-D70 PolarHBondContact N-OD2 2.88Å; S67-D70 VanDerWaalsContact N-OD2 3.15Å; S67-D70 PolarHBondContact O-N 3.16Å; C68-D70 VanDerWaalsContact C-N 3.26Å; C68-D70 PolarHBondContact O-N 3.11Å; D70-L72 VanDerWaalsContact C-N 3.34Å; D70-S73 PolarHBondContact O-N 3.32Å; D70-L74 PolarHBondContact O-N 2.92Å; D70-L74 VanDerWaalsContact O-N 3.09Å
71Y81.3Confident77.9Confident11 Ų1157.2 Ų57.24%0.04329%0.287CS..Hα-helixtrans-61.9-43.8170-56.1-57.7000111L57 Q60 I61 C68 S73 L74 I75 L103L57-Y71 HydrophobicContact CD1-CD1 3.81Å; L57-Y71 HydrophobicContact CD1-CE1 4.47Å; Q60-Y71 HydrophobicContact CB-CD1 4.4Å; Q60-Y71 HydrophobicContact CB-CE1 3.87Å; Q60-Y71 PolarHBondContact O-OH 3Å; I61-Y71 HydrophobicContact CG1-CD1 4.48Å; I61-Y71 HydrophobicContact CG1-CE1 3.77Å; C68-Y71 PolarHBondContact O-N 3.14Å; Y71-S73 VanDerWaalsContact C-N 3.32Å; Y71-S73 PolarHBondContact O-N 3.34Å; Y71-L74 PolarHBondContact O-N 2.92Å; Y71-I75 WeakPolarHBondContact O-CG1 3.46Å; Y71-I75 PolarHBondContact O-N 3.02Å; Y71-L103 HydrophobicContact CD2-CD1 4.44Å; Y71-L103 HydrophobicContact CE2-CD1 4.48Å; Y71-L103 HydrophobicContact CE2-CD2 4.43Å
72L82.8Confident78Confident22 Ų2256.4 Ų56.412%0.11528%0.284CS..Hα-helixtrans-65.2-36.2177.5-66.2-178.9000112.1C68 D70 L74 I75 Y76 I111 F114C68-L72 VanDerWaalsContact O-CG 3.31Å; C68-L72 WeakPolarHBondContact O-CG 3.35Å; C68-L72 PolarHBondContact O-N 2.91Å; C68-L72 VanDerWaalsContact O-N 3.15Å; D70-L72 VanDerWaalsContact C-N 3.34Å; L72-L74 VanDerWaalsContact C-N 3.34Å; L72-I75 PolarHBondContact O-N 3.17Å; L72-Y76 WeakPolarHBondContact O-CD2 3.46Å; L72-Y76 PolarHBondContact O-N 3.48Å; L72-I111 HydrophobicContact CD2-CG1 4.46Å; L72-I111 HydrophobicContact CD2-CG2 4.25Å; L72-F114 HydrophobicContact CB-CD2 4.44Å; L72-F114 HydrophobicContact CB-CE2 4.45Å; L72-F114 HydrophobicContact CD1-CB 4.08Å; L72-F114 HydrophobicContact CD1-CD2 4.17Å; L72-F114 HydrophobicContact CD1-CG 4.3Å; L72-F114 HydrophobicContact CD2-CB 3.81Å; L72-F114 HydrophobicContact CD2-CD1 3.65Å; L72-F114 HydrophobicContact CD2-CD2 3.73Å; L72-F114 HydrophobicContact CD2-CE1 4.11Å; L72-F114 HydrophobicContact CD2-CE2 4.1Å; L72-F114 HydrophobicContact CD2-CG 3.47Å; L72-F114 VanDerWaalsContact CD2-CG 3.47Å; L72-F114 HydrophobicContact CD2-CZ 4.31Å; L72-F114 HydrophobicContact CG-CD2 4.32Å; L72-F114 HydrophobicContact CG-CG 4.42Å
73S84.3Confident78Confident28 Ų2854.3 Ų54.320%0.19628%0.277CS..Hα-helixtrans-64.4-38.8176.1-63.50000111.7D69 D70 Y71 Y76 L77D69-S73 WeakPolarHBondContact O-CB 3.06Å; D69-S73 PolarHBondContact O-N 3.18Å; D69-S73 PolarHBondContact O-OG 2.76Å; D70-S73 PolarHBondContact O-N 3.32Å; Y71-S73 VanDerWaalsContact C-N 3.32Å; Y71-S73 PolarHBondContact O-N 3.34Å; S73-Y76 PolarHBondContact O-N 3.44Å; S73-L77 WeakPolarHBondContact O-CB 3.5Å; S73-L77 PolarHBondContact O-N 3.13Å
74L85.3Confident78.3Confident1 Ų154 Ų541%0.00528%0.276CS..Hα-helixtrans-65.7-40.4173.3-17655.6000112L23 L53 V56 L57 D70 Y71 L72 L77 S78L23-L74 HydrophobicContact CD1-CD1 4.1Å; L23-L74 HydrophobicContact CD2-CB 3.83Å; L23-L74 HydrophobicContact CD2-CD1 4Å; L23-L74 HydrophobicContact CD2-CG 4.48Å; L23-L74 HydrophobicContact CG-CD1 4.22Å; L53-L74 HydrophobicContact CD2-CD1 3.9Å; V56-L74 HydrophobicContact CG1-CD2 4.39Å; L57-L74 HydrophobicContact CB-CD2 3.65Å; L57-L74 HydrophobicContact CD1-CD2 3.94Å; L57-L74 HydrophobicContact CG-CD2 4.38Å; D70-L74 PolarHBondContact O-N 2.92Å; D70-L74 VanDerWaalsContact O-N 3.09Å; Y71-L74 PolarHBondContact O-N 2.92Å; L72-L74 VanDerWaalsContact C-N 3.34Å; L74-L77 HydrophobicContact CD1-CD2 4.41Å; L74-L77 WeakPolarHBondContact O-CB 3.34Å; L74-L77 PolarHBondContact O-N 3.26Å; L74-S78 PolarHBondContact O-N 3.16Å
75I86.7Confident79.2Confident0 Ų047.6 Ų47.60%026%0.256CS..Hα-helixtrans-65.9-43.2176.6-64.2170.3000110.5Y71 L72 L77 S78 I79 L96 F114Y71-I75 WeakPolarHBondContact O-CG1 3.46Å; Y71-I75 PolarHBondContact O-N 3.02Å; L72-I75 PolarHBondContact O-N 3.17Å; I75-L77 VanDerWaalsContact C-N 3.35Å; I75-L77 PolarHBondContact O-N 2.86Å; I75-S78 PolarHBondContact O-N 3.3Å; I75-S78 VanDerWaalsContact O-N 3.13Å; I75-S78 PolarHBondContact O-OG 2.89Å; I75-I79 HydrophobicContact CG2-CD1 4.18Å; I75-I79 WeakPolarHBondContact O-CG1 3.44Å; I75-I79 PolarHBondContact O-N 3.15Å; I75-L96 HydrophobicContact CD1-CB 4.2Å; I75-L96 HydrophobicContact CD1-CD1 3.71Å; I75-F114 HydrophobicContact CB-CZ 4.37Å; I75-F114 HydrophobicContact CG2-CE1 3.93Å; I75-F114 HydrophobicContact CG2-CZ 3.83Å
76Y87Confident80.6Confident103 Ų10338.9 Ų38.940%0.40422%0.218SC..Hα-helixtrans-57.7-46.5172.8-86.3-57.8000112L72 S73 S78 I79 D80 F114L72-Y76 WeakPolarHBondContact O-CD2 3.46Å; L72-Y76 PolarHBondContact O-N 3.48Å; S73-Y76 PolarHBondContact O-N 3.44Å; Y76-S78 PolarHBondContact O-N 3.46Å; Y76-I79 WeakPolarHBondContact O-CB 3.32Å; Y76-I79 PolarHBondContact O-N 3.01Å; Y76-I79 VanDerWaalsContact O-N 3.11Å; Y76-D80 PolarHBondContact O-N 3.34Å; Y76-F114 HydrophobicContact CD1-CE2 4.26Å; Y76-F114 AromaticContact CD2-CE2 3.82Å; Y76-F114 HydrophobicContact CD2-CE2 3.82Å; Y76-F114 AromaticContact CE1-CE2 3.79Å; Y76-F114 HydrophobicContact CE1-CE2 3.79Å; Y76-F114 HydrophobicContact CE1-CZ 4.38Å; Y76-F114 AromaticContact CE2-CD2 3.95Å; Y76-F114 HydrophobicContact CE2-CD2 3.95Å; Y76-F114 AromaticContact CE2-CE2 3.35Å; Y76-F114 HydrophobicContact CE2-CE2 3.35Å; Y76-F114 HydrophobicContact CE2-CZ 4.43Å; Y76-F114 HydrophobicContact CG-CE2 4.25Å; Y76-F114 AromaticContact CZ-CD2 3.92Å; Y76-F114 AromaticContact CZ-CE2 3.3Å
77L85.9Confident81.9Confident7 Ų737.3 Ų37.34%0.03721%0.209CC..Hα-helixtrans-57.9-39.7175.8-169.578.7000111.5A22 L23 C28 S73 L74 I75 D80 A81A22-L77 HydrophobicContact CB-CD1 4.01Å; A22-L77 HydrophobicContact CB-CD2 3.87Å; L23-L77 HydrophobicContact CG-CD2 4.35Å; C28-L77 HydrophobicContact CB-CD1 4.44Å; C28-L77 WeakPolarHBondContact SG-CD1 3.33Å; C28-L77 PolarHBondContact SG-O 2.7Å; C28-L77 VanDerWaalsContact SG-O 3.32Å; S73-L77 WeakPolarHBondContact O-CB 3.5Å; S73-L77 PolarHBondContact O-N 3.13Å; L74-L77 HydrophobicContact CD1-CD2 4.41Å; L74-L77 WeakPolarHBondContact O-CB 3.34Å; L74-L77 PolarHBondContact O-N 3.26Å; I75-L77 VanDerWaalsContact C-N 3.35Å; I75-L77 PolarHBondContact O-N 2.86Å; L77-D80 PolarHBondContact O-N 2.83Å; L77-A81 VanDerWaalsContact O-CB 3.29Å; L77-A81 WeakPolarHBondContact O-CB 3.23Å; L77-A81 PolarHBondContact O-N 3.24Å
78S86.3Confident82.8Confident0 Ų036.4 Ų36.40%020%0.203CC..Hα-helixtrans-68.1-36.3177.278.50000112.8L74 I75 Y76 A81 V82 P92L74-S78 PolarHBondContact O-N 3.16Å; I75-S78 PolarHBondContact O-N 3.3Å; I75-S78 VanDerWaalsContact O-N 3.13Å; I75-S78 PolarHBondContact O-OG 2.89Å; Y76-S78 PolarHBondContact O-N 3.46Å; S78-A81 PolarHBondContact O-N 3.02Å; S78-V82 WeakPolarHBondContact O-CG2 3.38Å; S78-V82 PolarHBondContact O-N 2.88Å; S78-V82 VanDerWaalsContact O-N 3.07Å; S78-P92 WeakPolarHBondContact OG-CB 3.32Å
79I86.2Confident83.6Confident11 Ų1136.7 Ų36.76%0.05621%0.207CC..Hα-helixtrans-65.1-48.5174.8-66.9166.7000109.5I75 Y76 A81 V82 T83 P92 F114 T121 W122 F127I75-I79 HydrophobicContact CG2-CD1 4.18Å; I75-I79 WeakPolarHBondContact O-CG1 3.44Å; I75-I79 PolarHBondContact O-N 3.15Å; Y76-I79 WeakPolarHBondContact O-CB 3.32Å; Y76-I79 PolarHBondContact O-N 3.01Å; Y76-I79 VanDerWaalsContact O-N 3.11Å; I79-A81 VanDerWaalsContact C-N 3.32Å; I79-A81 PolarHBondContact O-N 3.44Å; I79-V82 PolarHBondContact O-N 3.1Å; I79-V82 VanDerWaalsContact O-N 3.13Å; I79-T83 PolarHBondContact O-N 3.3Å; I79-P92 HydrophobicContact CG1-CB 4.01Å; I79-P92 HydrophobicContact CG1-CG 4.23Å; I79-F114 HydrophobicContact CD1-CZ 4.49Å; I79-T121 HydrophobicContact CG2-CG2 3.88Å; I79-W122 HydrophobicContact CD1-CH2 3.72Å; I79-W122 HydrophobicContact CD1-CZ2 4.28Å; I79-W122 HydrophobicContact CD1-CZ3 4.29Å; I79-W122 HydrophobicContact CG1-CH2 4.19Å; I79-W122 HydrophobicContact CG1-CZ3 4.4Å; I79-F127 HydrophobicContact CG2-CE2 4.42Å; I79-F127 HydrophobicContact CG2-CZ 4.07Å
80D85.1Confident84.2Confident75 Ų7533.6 Ų33.640%0.40119%0.191SC..Hα-helixtrans-60.7-42.7178.5-72.1-8.2000111C28 Y76 L77 V82 T83 E84C28-D80 HydrophobicContact CB-CB 4.45Å; C28-D80 WeakPolarHBondContact SG-CB 3.49Å; Y76-D80 PolarHBondContact O-N 3.34Å; L77-D80 PolarHBondContact O-N 2.83Å; D80-V82 VanDerWaalsContact C-N 3.29Å; D80-V82 PolarHBondContact O-N 3.47Å; D80-T83 VanDerWaalsContact CA-OG1 3.31Å; D80-T83 WeakPolarHBondContact CA-OG1 3.39Å; D80-T83 PolarHBondContact O-N 3.41Å; D80-T83 VanDerWaalsContact O-N 3.15Å; D80-T83 PolarHBondContact O-OG1 3.37Å; D80-E84 WeakPolarHBondContact O-CG 3.48Å; D80-E84 PolarHBondContact O-N 3.44Å
81A84.2Confident84.8Confident0 Ų030.9 Ų30.90%018%0.177CC..Hα-helixtrans-64-31.7176.900000113.1L31 L77 S78 I79 G85 I86 C87L31-A81 HydrophobicContact CD2-CB 4.23Å; L77-A81 VanDerWaalsContact O-CB 3.29Å; L77-A81 WeakPolarHBondContact O-CB 3.23Å; L77-A81 PolarHBondContact O-N 3.24Å; S78-A81 PolarHBondContact O-N 3.02Å; I79-A81 VanDerWaalsContact C-N 3.32Å; I79-A81 PolarHBondContact O-N 3.44Å; A81-G85 PolarHBondContact O-N 3.46Å; A81-I86 WeakPolarHBondContact O-CB 3.39Å; A81-I86 PolarHBondContact O-N 3.27Å; A81-C87 HydrophobicContact CB-CB 4.24Å; A81-C87 VanDerWaalsContact CB-SG 3.57Å; A81-C87 PolarHBondContact O-N 3Å
82V84.2Confident85.3Confident16 Ų1630.3 Ų30.310%0.09718%0.175CC..Hα-helixtrans-72.6-40.7171.6173.10000111.2S78 I79 D80 E84 G85 C87 S88 A89 I91 P92 F127S78-V82 WeakPolarHBondContact O-CG2 3.38Å; S78-V82 PolarHBondContact O-N 2.88Å; S78-V82 VanDerWaalsContact O-N 3.07Å; I79-V82 PolarHBondContact O-N 3.1Å; I79-V82 VanDerWaalsContact O-N 3.13Å; D80-V82 VanDerWaalsContact C-N 3.29Å; D80-V82 PolarHBondContact O-N 3.47Å; V82-E84 PolarHBondContact O-N 3.39Å; V82-G85 WeakPolarHBondContact O-CA 3.41Å; V82-G85 PolarHBondContact O-N 3.06Å; V82-C87 HydrophobicContact CG2-CB 3.77Å; V82-S88 WeakPolarHBondContact CG2-O 3.34Å; V82-A89 HydrophobicContact CG1-CB 4.19Å; V82-I91 HydrophobicContact CG2-CG2 4.17Å; V82-P92 HydrophobicContact CG2-CG 4.05Å; V82-F127 HydrophobicContact CB-CE1 3.72Å; V82-F127 HydrophobicContact CB-CZ 3.71Å; V82-F127 HydrophobicContact CG1-CD1 4.29Å; V82-F127 HydrophobicContact CG1-CE1 3.35Å; V82-F127 HydrophobicContact CG1-CE2 4.46Å; V82-F127 HydrophobicContact CG1-CZ 3.46Å; V82-F127 VanDerWaalsContact CG1-CZ 3.46Å; V82-F127 HydrophobicContact CG2-CE1 4.2Å
83T83.6Confident85.7Confident89 Ų8929.5 Ų29.555%0.54617%0.17SC..Hα-helixtrans-63-31.8177.753.80000112.7I79 D80 G85 F127I79-T83 PolarHBondContact O-N 3.3Å; D80-T83 VanDerWaalsContact CA-OG1 3.31Å; D80-T83 WeakPolarHBondContact CA-OG1 3.39Å; D80-T83 PolarHBondContact O-N 3.41Å; D80-T83 VanDerWaalsContact O-N 3.15Å; D80-T83 PolarHBondContact O-OG1 3.37Å; T83-G85 VanDerWaalsContact C-N 3.26Å; T83-G85 PolarHBondContact O-N 3.48Å; T83-F127 HydrophobicContact CG2-CE2 4.12Å; T83-F127 HydrophobicContact CG2-CZ 4.28Å
84E83.3Confident86Confident122 Ų12229.7 Ų29.757%0.5717%0.17SC*.THydrogen-bonded Turntrans-81.5-2.1173.9-64-69.7156.300113I32 D80 V82 I86I32-E84 HydrophobicContact CD1-CB 4.11Å; I32-E84 HydrophobicContact CD1-CG 3.82Å; D80-E84 WeakPolarHBondContact O-CG 3.48Å; D80-E84 PolarHBondContact O-N 3.44Å; V82-E84 PolarHBondContact O-N 3.39Å; E84-I86 HydrophobicContact CB-CD1 3.73Å; E84-I86 HydrophobicContact CB-CG1 3.95Å
85G81.8Confident86.3Confident38 Ų3829.7 Ų29.739%0.39217%0.17SC..THydrogen-bonded Turntrans80.113.9175.200000115.7K46 A81 V82 T83K46-G85 WeakPolarHBondContact CE-O 3.43Å; K46-G85 PolarHBondContact NZ-O 2.86Å; A81-G85 PolarHBondContact O-N 3.46Å; V82-G85 WeakPolarHBondContact O-CA 3.41Å; V82-G85 PolarHBondContact O-N 3.06Å; T83-G85 VanDerWaalsContact C-N 3.26Å; T83-G85 PolarHBondContact O-N 3.48Å
86I81.3Confident86.5Confident7 Ų729.7 Ų29.74%0.03617%0.17CC..SBendtrans-94.3-26.9-169.9-50.8171.6000112I32 F35 K46 L49 A81 E84I32-I86 HydrophobicContact CB-CD1 3.75Å; I32-I86 HydrophobicContact CD1-CD1 3.79Å; I32-I86 HydrophobicContact CG1-CD1 3.34Å; I32-I86 HydrophobicContact CG2-CD1 3.78Å; F35-I86 HydrophobicContact CB-CG2 3.75Å; F35-I86 HydrophobicContact CD1-CG2 3.81Å; F35-I86 HydrophobicContact CD2-CG2 3.34Å; F35-I86 HydrophobicContact CE1-CG2 4.19Å; F35-I86 HydrophobicContact CE2-CG2 3.74Å; F35-I86 WeakPolarHBondContact CE2-O 3.47Å; F35-I86 HydrophobicContact CG-CG2 3.37Å; F35-I86 HydrophobicContact CZ-CG2 4.15Å; K46-I86 WeakPolarHBondContact CG-O 3.21Å; L49-I86 HydrophobicContact CD2-CG2 3.59Å; A81-I86 WeakPolarHBondContact O-CB 3.39Å; A81-I86 PolarHBondContact O-N 3.27Å; E84-I86 HydrophobicContact CB-CD1 3.73Å; E84-I86 HydrophobicContact CB-CG1 3.95Å
87C82.4Confident86.7Confident6 Ų625.3 Ų25.34%0.04116%0.156CC..SBendtrans-113.6165.2177.4-70.20000112.3L49 A81 V82 I91L49-C87 WeakPolarHBondContact CD2-SG 3.2Å; A81-C87 HydrophobicContact CB-CB 4.24Å; A81-C87 VanDerWaalsContact CB-SG 3.57Å; A81-C87 PolarHBondContact O-N 3Å; V82-C87 HydrophobicContact CG2-CB 3.77Å; C87-I91 HydrophobicContact CB-CG2 3.83Å
88S85.6Confident86.8Confident38 Ų3826.7 Ų26.727%0.26616%0.164SC..  trans-69.1140.9169.5-1800000111.1D50 V82 T90 I91D50-S88 PolarHBondContact OD1-N 3.31Å; D50-S88 WeakPolarHBondContact OD2-CB 3.29Å; V82-S88 WeakPolarHBondContact CG2-O 3.34Å; S88-T90 PolarHBondContact O-N 3.26Å; S88-T90 PolarHBondContact OG-N 3.48Å; S88-T90 PolarHBondContact OG-OG1 3.13Å; S88-I91 WeakPolarHBondContact O-CG2 3.22Å; S88-I91 PolarHBondContact O-N 3.32Å; S88-I91 VanDerWaalsContact O-N 3.1Å
89A85.3Confident87Confident27 Ų2726.7 Ų26.722%0.22316%0.164CC..THydrogen-bonded Turntrans-60.5-13.9176.300000114.1V82 F93 A130V82-A89 HydrophobicContact CG1-CB 4.19Å; A89-F93 WeakPolarHBondContact O-CD2 3.46Å; A89-F93 WeakPolarHBondContact O-CE2 3.36Å; A89-A130 HydrophobicContact CB-CB 3.86Å
90T89Confident87.2Confident39 Ų3926.2 Ų26.224%0.23916%0.161CC..THydrogen-bonded Turntrans-83.9-23.3178.156.40000113.9S88 P92 F93 V94 A130 Y134S88-T90 PolarHBondContact O-N 3.26Å; S88-T90 PolarHBondContact OG-N 3.48Å; S88-T90 PolarHBondContact OG-OG1 3.13Å; T90-P92 VanDerWaalsContact C-CD 3.48Å; T90-F93 PolarHBondContact O-N 3.31Å; T90-V94 PolarHBondContact O-N 3.15Å; T90-A130 HydrophobicContact CG2-CB 4.22Å; T90-Y134 HydrophobicContact CG2-CE2 3.87Å
91I89.9Confident87.4Confident8 Ų826.7 Ų26.74%0.04116%0.164CC..Hα-helixtrans-61.3-41.4-169-163.956.2000114.1D50 L53 V82 C87 S88 F93 V94 L95D50-I91 HydrophobicContact CB-CD1 3.87Å; D50-I91 HydrophobicContact CB-CG1 4.16Å; L53-I91 HydrophobicContact CD1-CG1 4.45Å; V82-I91 HydrophobicContact CG2-CG2 4.17Å; C87-I91 HydrophobicContact CB-CG2 3.83Å; S88-I91 WeakPolarHBondContact O-CG2 3.22Å; S88-I91 PolarHBondContact O-N 3.32Å; S88-I91 VanDerWaalsContact O-N 3.1Å; I91-F93 PolarHBondContact O-N 2.94Å; I91-V94 PolarHBondContact O-N 2.95Å; I91-L95 HydrophobicContact CD1-CD2 4.34Å; I91-L95 HydrophobicContact CD1-CG 4.1Å; I91-L95 HydrophobicContact CG1-CD1 4Å; I91-L95 HydrophobicContact CG1-CG 4.07Å; I91-L95 WeakPolarHBondContact O-CG 3.27Å; I91-L95 PolarHBondContact O-N 2.91Å
92P90.5Very high87.6Confident0 Ų030.4 Ų30.40%019%0.189CC..Hα-helixtrans-63.9-33.1-177.7-20.635.2000111.9S78 I79 V82 T90 L96 W122 F127S78-P92 WeakPolarHBondContact OG-CB 3.32Å; I79-P92 HydrophobicContact CG1-CB 4.01Å; I79-P92 HydrophobicContact CG1-CG 4.23Å; V82-P92 HydrophobicContact CG2-CG 4.05Å; T90-P92 VanDerWaalsContact C-CD 3.48Å; P92-L96 WeakPolarHBondContact O-CB 3.41Å; P92-L96 PolarHBondContact O-N 3.21Å; P92-W122 HydrophobicContact CB-CH2 4.38Å; P92-W122 HydrophobicContact CB-CZ3 4.28Å; P92-F127 HydrophobicContact CG-CE1 4.21Å
93F91.7Very high87.6Confident4 Ų430.4 Ų30.42%0.01819%0.188CC..Hα-helixtrans-73.4-38178.3-57.1-71.5000112.6A89 T90 I91 G97 W122 F127 G131 Y134 L135A89-F93 WeakPolarHBondContact O-CD2 3.46Å; A89-F93 WeakPolarHBondContact O-CE2 3.36Å; T90-F93 PolarHBondContact O-N 3.31Å; I91-F93 PolarHBondContact O-N 2.94Å; F93-G97 PolarHBondContact O-N 3.39Å; F93-W122 HydrophobicContact CD1-CE3 4.28Å; F93-W122 HydrophobicContact CD1-CZ3 4.15Å; F93-W122 HydrophobicContact CE1-CD2 4Å; F93-W122 AromaticContact CE1-CE3 3.26Å; F93-W122 HydrophobicContact CE1-CE3 3.26Å; F93-W122 HydrophobicContact CE1-CH2 4.43Å; F93-W122 AromaticContact CE1-CZ3 3.51Å; F93-W122 HydrophobicContact CE1-CZ3 3.51Å; F93-W122 HydrophobicContact CZ-CD2 4.48Å; F93-W122 AromaticContact CZ-CE3 3.46Å; F93-W122 HydrophobicContact CZ-CE3 3.46Å; F93-W122 VanDerWaalsContact CZ-CE3 3.46Å; F93-W122 AromaticContact CZ-CZ3 3.75Å; F93-W122 HydrophobicContact CZ-CZ3 3.75Å; F93-F127 HydrophobicContact CE2-CB 4.37Å; F93-F127 HydrophobicContact CE2-CD1 4.07Å; F93-F127 HydrophobicContact CZ-CB 4.05Å; F93-F127 HydrophobicContact CZ-CD1 4.3Å; F93-G131 VanDerWaalsContact CD2-CA 3.44Å; F93-G131 VanDerWaalsContact CZ-CA 3.47Å; F93-Y134 HydrophobicContact CB-CD2 4.3Å; F93-Y134 HydrophobicContact CB-CG 4.03Å; F93-L135 HydrophobicContact CD1-CD1 4.35Å; F93-L135 HydrophobicContact CD1-CD2 3.82Å; F93-L135 HydrophobicContact CD1-CG 3.79Å; F93-L135 HydrophobicContact CE1-CD1 3.81Å; F93-L135 HydrophobicContact CE1-CD2 4Å; F93-L135 HydrophobicContact CE1-CG 3.77Å
94V91.5Very high87.8Confident33 Ų3330 Ų3020%0.219%0.188CC..Hα-helixtrans-67.1-46.1176175.90000110.1T90 I91 L96 G97 D98 Y134T90-V94 PolarHBondContact O-N 3.15Å; I91-V94 PolarHBondContact O-N 2.95Å; V94-L96 PolarHBondContact O-N 3.25Å; V94-G97 PolarHBondContact O-N 3.42Å; V94-D98 VanDerWaalsContact O-CG 3.25Å; V94-D98 PolarHBondContact O-N 3.48Å; V94-Y134 HydrophobicContact CG2-CD1 4.38Å; V94-Y134 HydrophobicContact CG2-CE1 4Å
95L90.5Very high87.8Confident0 Ų026.7 Ų26.70%017%0.173CC..Hα-helixtrans-60.5-44.8176.3-65.6176.3000111.5L53 R54 L57 I91 G97 D98 V99L53-L95 HydrophobicContact CB-CD1 4.36Å; R54-L95 HydrophobicContact CB-CD2 4.08Å; R54-L95 HydrophobicContact CG-CD2 4.23Å; L57-L95 HydrophobicContact CB-CD2 4.16Å; L57-L95 HydrophobicContact CD2-CB 4.12Å; L57-L95 HydrophobicContact CD2-CD2 3.65Å; L57-L95 HydrophobicContact CD2-CG 4.48Å; I91-L95 HydrophobicContact CD1-CD2 4.34Å; I91-L95 HydrophobicContact CD1-CG 4.1Å; I91-L95 HydrophobicContact CG1-CD1 4Å; I91-L95 HydrophobicContact CG1-CG 4.07Å; I91-L95 WeakPolarHBondContact O-CG 3.27Å; I91-L95 PolarHBondContact O-N 2.91Å; L95-G97 VanDerWaalsContact C-N 3.34Å; L95-G97 PolarHBondContact O-N 3.48Å; L95-D98 PolarHBondContact O-N 2.99Å; L95-V99 WeakPolarHBondContact O-CB 3.33Å; L95-V99 VanDerWaalsContact O-CG2 3.23Å; L95-V99 WeakPolarHBondContact O-CG2 3.43Å; L95-V99 PolarHBondContact O-N 3.23Å
96L91Very high87.9Confident0 Ų031 Ų310%019%0.188CC..Hα-helixtrans-62.8-40.6176.8-176.471.1000112.1I75 P92 V94 L100 I111 V115 M138I75-L96 HydrophobicContact CD1-CB 4.2Å; I75-L96 HydrophobicContact CD1-CD1 3.71Å; P92-L96 WeakPolarHBondContact O-CB 3.41Å; P92-L96 PolarHBondContact O-N 3.21Å; V94-L96 PolarHBondContact O-N 3.25Å; L96-L100 HydrophobicContact CD1-CD1 4.39Å; L96-L100 HydrophobicContact CG-CD1 4.13Å; L96-L100 WeakPolarHBondContact O-CG 3.4Å; L96-L100 PolarHBondContact O-N 3.49Å; L96-I111 HydrophobicContact CD1-CG2 3.81Å; L96-V115 HydrophobicContact CD1-CG2 3.82Å; L96-V115 HydrophobicContact CD2-CG1 4.4Å; L96-V115 HydrophobicContact CD2-CG2 3.6Å; L96-V115 HydrophobicContact CG-CG2 4.26Å; L96-M138 HydrophobicContact CB-SD 4.32Å; L96-M138 HydrophobicContact CD2-CE 3.66Å; L96-M138 HydrophobicContact CD2-SD 3.58Å; L96-M138 VanDerWaalsContact CD2-SD 3.58Å; L96-M138 HydrophobicContact CG-CE 4.33Å; L96-M138 HydrophobicContact CG-SD 3.65Å
97G90.6Very high88Confident12 Ų1233.4 Ų33.412%0.12420%0.2CC..Hα-helixtrans-61.6-51.1174.500000112.1F93 V94 L95 V99 L100 D101F93-G97 PolarHBondContact O-N 3.39Å; V94-G97 PolarHBondContact O-N 3.42Å; L95-G97 VanDerWaalsContact C-N 3.34Å; L95-G97 PolarHBondContact O-N 3.48Å; G97-V99 VanDerWaalsContact C-N 3.31Å; G97-V99 PolarHBondContact O-N 3.26Å; G97-L100 PolarHBondContact O-N 2.82Å; G97-L100 VanDerWaalsContact O-N 3.16Å; G97-D101 WeakPolarHBondContact O-CB 3.49Å; G97-D101 PolarHBondContact O-N 2.77Å
98D89.9Confident88.2Confident35 Ų3533.1 Ų33.119%0.18720%0.198CC..Hα-helixtrans-57.8-43.3177.8-67.9-26.6000111.5R54 L57 V94 L95 D101 C102R54-D98 IonicContact CZ-OD1 2.89Å; R54-D98 IonicContact CZ-OD2 3.34Å; R54-D98 VanDerWaalsContact CZ-OD2 3.28Å; R54-D98 IonicContact NE-OD1 2.71Å; R54-D98 IonicContact NE-OD2 2.59Å; R54-D98 PolarHBondContact NE-OD2 3.26Å; R54-D98 VanDerWaalsContact NH2-CG 3.34Å; R54-D98 IonicContact NH2-OD1 3.81Å; R54-D98 PolarHBondContact NH2-OD1 3.37Å; R54-D98 IonicContact NH2-OD2 3.65Å; R54-D98 PolarHBondContact NH2-OD2 3.47Å; R54-D98 VanDerWaalsContact NH2-OD2 3.08Å; L57-D98 HydrophobicContact CD2-CB 4.12Å; V94-D98 VanDerWaalsContact O-CG 3.25Å; V94-D98 PolarHBondContact O-N 3.48Å; L95-D98 PolarHBondContact O-N 2.99Å; D98-D101 PolarHBondContact O-N 3.34Å; D98-C102 WeakPolarHBondContact O-CB 3.4Å; D98-C102 PolarHBondContact O-N 2.74Å; D98-C102 PolarHBondContact O-SG 2.84Å
99V89.6Confident88.3Confident1 Ų134 Ų341%0.00620%0.2CC..Hα-helixtrans-59.5-50175.7168.30000110.9L57 L95 G97 D101 C102 L103 I111L57-V99 HydrophobicContact CD1-CG2 3.5Å; L57-V99 HydrophobicContact CD2-CG2 3.76Å; L57-V99 HydrophobicContact CG-CG2 4.17Å; L95-V99 WeakPolarHBondContact O-CB 3.33Å; L95-V99 VanDerWaalsContact O-CG2 3.23Å; L95-V99 WeakPolarHBondContact O-CG2 3.43Å; L95-V99 PolarHBondContact O-N 3.23Å; G97-V99 VanDerWaalsContact C-N 3.31Å; G97-V99 PolarHBondContact O-N 3.26Å; V99-D101 VanDerWaalsContact C-N 3.32Å; V99-D101 PolarHBondContact O-N 2.98Å; V99-C102 PolarHBondContact O-N 3.36Å; V99-L103 HydrophobicContact CG1-CD1 3.53Å; V99-L103 HydrophobicContact CG1-CG 4.38Å; V99-L103 WeakPolarHBondContact O-CB 3.4Å; V99-L103 WeakPolarHBondContact O-CG 3.42Å; V99-L103 PolarHBondContact O-N 2.78Å; V99-I111 HydrophobicContact CG1-CD1 3.57Å
100L89.8Confident88.3Confident0 Ų039.1 Ų39.10%022%0.217CC..Hα-helixtrans-66.5-36.9-177.6-72.7166.6000111.6L96 G97 C108 I111 M138 L142 R145L96-L100 HydrophobicContact CD1-CD1 4.39Å; L96-L100 HydrophobicContact CG-CD1 4.13Å; L96-L100 WeakPolarHBondContact O-CG 3.4Å; L96-L100 PolarHBondContact O-N 3.49Å; G97-L100 PolarHBondContact O-N 2.82Å; G97-L100 VanDerWaalsContact O-N 3.16Å; L100-C108 HydrophobicContact CD2-CB 3.77Å; L100-C108 PolarHBondContact O-SG 3.38Å; L100-C108 VanDerWaalsContact O-SG 3.35Å; L100-I111 HydrophobicContact CD2-CB 4.17Å; L100-I111 HydrophobicContact CD2-CG2 3.92Å; L100-I111 HydrophobicContact CG-CG2 4.38Å; L100-M138 HydrophobicContact CD1-CE 4.14Å; L100-M138 HydrophobicContact CD1-CG 3.48Å; L100-M138 VanDerWaalsContact CD1-CG 3.48Å; L100-M138 HydrophobicContact CD1-SD 3.35Å; L100-M138 WeakPolarHBondContact CD1-SD 3.33Å; L100-L142 HydrophobicContact CD1-CD1 4.2Å; L100-R145 PolarHBondContact O-NH1 3.06Å; L100-R145 PolarHBondContact O-NH2 3.48Å
101D89.6Confident88.3Confident85 Ų8537.2 Ų37.246%0.45521%0.206SC..Hα-helixtrans-68.4-35.1178.6-74.1-20.2000113.1G97 D98 V99 R145G97-D101 WeakPolarHBondContact O-CB 3.49Å; G97-D101 PolarHBondContact O-N 2.77Å; D98-D101 PolarHBondContact O-N 3.34Å; V99-D101 VanDerWaalsContact C-N 3.32Å; V99-D101 PolarHBondContact O-N 2.98Å; D101-R145 IonicContact OD1-NH1 3.46Å
102C87.8Confident88.3Confident79 Ų7936.9 Ų36.953%0.53420%0.204SC..Hα-helixtrans-82.8-17179.3-67.30000114.5I61 D98 V99I61-C102 HydrophobicContact CD1-CB 4.12Å; I61-C102 HydrophobicContact CG2-CB 3.92Å; D98-C102 WeakPolarHBondContact O-CB 3.4Å; D98-C102 PolarHBondContact O-N 2.74Å; D98-C102 PolarHBondContact O-SG 2.84Å; V99-C102 PolarHBondContact O-N 3.36Å
103L85.6Confident88.3Confident15 Ų1538.6 Ų38.68%0.07922%0.216CC..SBendtrans-98.9151.1-173.4-68.1178000114.2Y71 V99 L107 I111 R145Y71-L103 HydrophobicContact CD2-CD1 4.44Å; Y71-L103 HydrophobicContact CE2-CD1 4.48Å; Y71-L103 HydrophobicContact CE2-CD2 4.43Å; V99-L103 HydrophobicContact CG1-CD1 3.53Å; V99-L103 HydrophobicContact CG1-CG 4.38Å; V99-L103 WeakPolarHBondContact O-CB 3.4Å; V99-L103 WeakPolarHBondContact O-CG 3.42Å; V99-L103 PolarHBondContact O-N 2.78Å; L103-L107 HydrophobicContact CB-CB 4.4Å; L103-L107 HydrophobicContact CD1-CB 4.35Å; L103-L107 HydrophobicContact CD2-CD1 4.17Å; L103-I111 HydrophobicContact CD1-CD1 3.23Å; L103-R145 PolarHBondContact O-NH2 3.35Å
104P86.7Confident88.1Confident82 Ų8239 Ų3953%0.53222%0.217SC..  trans-63.5158.6168.2-20.332.5000113.2D106 L107 C108P104-D106 VanDerWaalsContact C-N 3.33Å; P104-D106 PolarHBondContact O-N 2.94Å; P104-L107 PolarHBondContact O-N 3.11Å; P104-L107 VanDerWaalsContact O-N 3.16Å; P104-C108 PolarHBondContact O-N 3.29Å; P104-C108 VanDerWaalsContact O-N 3.11Å; P104-C108 PolarHBondContact O-SG 3.34Å; P104-C108 VanDerWaalsContact O-SG 3.35Å
105L83.4Confident88Confident51 Ų5137.4 Ų37.427%0.26721%0.208SC..Hα-helixtrans-58.7-37.5-172.4-64.3177.2000114L107 C108 D109 R145 L146L105-L107 VanDerWaalsContact C-N 3.29Å; L105-L107 PolarHBondContact O-N 2.71Å; L105-C108 WeakPolarHBondContact O-CB 3.45Å; L105-C108 PolarHBondContact O-N 3.45Å; L105-D109 PolarHBondContact O-N 3.42Å; L105-D109 VanDerWaalsContact O-N 3.07Å; L105-R145 HydrophobicContact CD2-CB 4.48Å; L105-L146 HydrophobicContact CD1-CD2 4.05Å; L105-L146 HydrophobicContact CD2-CD2 3.7Å; L105-L146 HydrophobicContact CD2-CG 4.4Å; L105-L146 HydrophobicContact CG-CD2 4.32Å
106D83.6Confident87.9Confident130 Ų13039.7 Ų39.770%0.69522%0.219SC*.Hα-helixtrans-64.9-34-178.8-55.5-38.9000112.7P104P104-D106 VanDerWaalsContact C-N 3.33Å; P104-D106 PolarHBondContact O-N 2.94Å
107L84.4Confident87.9Confident56 Ų5647.6 Ų47.629%0.29325%0.253SS..Hα-helixtrans-80.3-34.4176.7-58.5-177000110.9L103 P104 L105 D109 K110 I111L103-L107 HydrophobicContact CB-CB 4.4Å; L103-L107 HydrophobicContact CD1-CB 4.35Å; L103-L107 HydrophobicContact CD2-CD1 4.17Å; P104-L107 PolarHBondContact O-N 3.11Å; P104-L107 VanDerWaalsContact O-N 3.16Å; L105-L107 VanDerWaalsContact C-N 3.29Å; L105-L107 PolarHBondContact O-N 2.71Å; L107-D109 PolarHBondContact O-N 3.16Å; L107-K110 PolarHBondContact O-N 3.07Å; L107-I111 WeakPolarHBondContact O-CG1 3.32Å; L107-I111 PolarHBondContact O-N 2.93Å
108C87.1Confident87.7Confident0 Ų048 Ų480%025%0.252CS..Hα-helixtrans-58-37.4172.7-67.40000111.8L100 P104 L105 I111 F112 L142L100-C108 HydrophobicContact CD2-CB 3.77Å; L100-C108 PolarHBondContact O-SG 3.38Å; L100-C108 VanDerWaalsContact O-SG 3.35Å; P104-C108 PolarHBondContact O-N 3.29Å; P104-C108 VanDerWaalsContact O-N 3.11Å; P104-C108 PolarHBondContact O-SG 3.34Å; P104-C108 VanDerWaalsContact O-SG 3.35Å; L105-C108 WeakPolarHBondContact O-CB 3.45Å; L105-C108 PolarHBondContact O-N 3.45Å; C108-I111 PolarHBondContact O-N 3.17Å; C108-F112 VanDerWaalsContact O-CB 3.27Å; C108-F112 WeakPolarHBondContact O-CB 3.4Å; C108-F112 PolarHBondContact O-N 3.43Å; C108-L142 HydrophobicContact CB-CD2 4.28Å
109D86.4Confident87.5Confident57 Ų5746.5 Ų46.531%0.30525%0.245SC..Hα-helixtrans-63.3-43.4176.7-17323.7000112.6L105 L107 I111 F112 S113 F154 R157L105-D109 PolarHBondContact O-N 3.42Å; L105-D109 VanDerWaalsContact O-N 3.07Å; L107-D109 PolarHBondContact O-N 3.16Å; D109-I111 PolarHBondContact O-N 3.36Å; D109-F112 PolarHBondContact O-N 3.32Å; D109-S113 PolarHBondContact O-N 3.01Å; D109-S113 VanDerWaalsContact O-N 3.09Å; D109-S113 PolarHBondContact O-OG 3.31Å; D109-F154 HydrophobicContact CB-CD2 4.44Å; D109-F154 HydrophobicContact CB-CE2 4.29Å; D109-F154 HydrophobicContact CB-CZ 4.39Å; D109-F154 WeakPolarHBondContact OD1-CD2 3.35Å; D109-R157 IonicContact OD1-CZ 3.76Å; D109-R157 IonicContact OD1-NH1 3.89Å; D109-R157 PolarHBondContact OD1-NH1 2.8Å; D109-R157 IonicContact OD1-NH2 2.79Å; D109-R157 IonicContact OD2-NH1 3.72Å
110K86.6Confident87.3Confident134 Ų13450.8 Ų50.858%0.58328%0.275SS*.Hα-helixtrans-62.1-43.4175.1-66.4-179.7-177.5175.90111.7L107 S113L107-K110 PolarHBondContact O-N 3.07Å; K110-S113 WeakPolarHBondContact O-CB 3.31Å; K110-S113 PolarHBondContact O-N 2.96Å
111I88.1Confident87.1Confident0 Ų052.6 Ų52.60%029%0.286CS..Hα-helixtrans-69.9-37.5179.5-67.2166.9000110.8L72 L96 V99 L100 L103 L107 C108 D109 S113 F114 V115L72-I111 HydrophobicContact CD2-CG1 4.46Å; L72-I111 HydrophobicContact CD2-CG2 4.25Å; L96-I111 HydrophobicContact CD1-CG2 3.81Å; V99-I111 HydrophobicContact CG1-CD1 3.57Å; L100-I111 HydrophobicContact CD2-CB 4.17Å; L100-I111 HydrophobicContact CD2-CG2 3.92Å; L100-I111 HydrophobicContact CG-CG2 4.38Å; L103-I111 HydrophobicContact CD1-CD1 3.23Å; L107-I111 WeakPolarHBondContact O-CG1 3.32Å; L107-I111 PolarHBondContact O-N 2.93Å; C108-I111 PolarHBondContact O-N 3.17Å; D109-I111 PolarHBondContact O-N 3.36Å; I111-S113 PolarHBondContact O-N 3.42Å; I111-F114 WeakPolarHBondContact O-CA 3.37Å; I111-F114 VanDerWaalsContact O-CB 3.26Å; I111-F114 WeakPolarHBondContact O-CB 3.24Å; I111-F114 PolarHBondContact O-N 3.02Å; I111-V115 PolarHBondContact O-N 3.15Å
112F90.6Very high86.9Confident0 Ų048.6 Ų48.60%026%0.264CS..Hα-helixtrans-63.2-34.1176.3-162.8-98.2000112C108 D109 F114 V115 E116 L142 F154 I158 F161C108-F112 VanDerWaalsContact O-CB 3.27Å; C108-F112 WeakPolarHBondContact O-CB 3.4Å; C108-F112 PolarHBondContact O-N 3.43Å; D109-F112 PolarHBondContact O-N 3.32Å; F112-F114 PolarHBondContact O-N 3.29Å; F112-V115 WeakPolarHBondContact O-CA 3.39Å; F112-V115 WeakPolarHBondContact O-CB 3.34Å; F112-V115 PolarHBondContact O-N 3.01Å; F112-E116 HydrophobicContact CD1-CG 3.9Å; F112-E116 HydrophobicContact CE1-CG 3.74Å; F112-E116 WeakPolarHBondContact O-CG 3.47Å; F112-E116 PolarHBondContact O-N 3.45Å; F112-L142 HydrophobicContact CD2-CD1 4.1Å; F112-L142 HydrophobicContact CE2-CD1 4.43Å; F112-F154 HydrophobicContact CB-CE2 3.61Å; F112-F154 HydrophobicContact CB-CZ 3.88Å; F112-F154 AromaticContact CD1-CE2 3.8Å; F112-F154 HydrophobicContact CD1-CE2 3.8Å; F112-F154 HydrophobicContact CD2-CE2 4.5Å; F112-F154 AromaticContact CG-CE2 3.7Å; F112-F154 HydrophobicContact CG-CE2 3.7Å; F112-F154 HydrophobicContact CG-CZ 4.12Å; F112-I158 HydrophobicContact CD1-CG1 4.38Å; F112-I158 HydrophobicContact CD2-CG1 4.35Å; F112-I158 HydrophobicContact CE1-CB 4.49Å; F112-I158 HydrophobicContact CE1-CG1 3.92Å; F112-I158 HydrophobicContact CE2-CG1 3.9Å; F112-I158 HydrophobicContact CZ-CB 4.09Å; F112-I158 HydrophobicContact CZ-CG1 3.68Å; F112-I158 HydrophobicContact CZ-CG2 4.38Å; F112-F161 HydrophobicContact CE1-CB 3.97Å; F112-F161 HydrophobicContact CE1-CG 4.36Å; F112-F161 HydrophobicContact CE2-CD1 4.4Å; F112-F161 HydrophobicContact CZ-CB 3.67Å; F112-F161 AromaticContact CZ-CD1 3.88Å; F112-F161 HydrophobicContact CZ-CD1 3.88Å; F112-F161 AromaticContact CZ-CG 3.77Å; F112-F161 HydrophobicContact CZ-CG 3.77Å
113S89.6Confident86.7Confident36 Ų3649.7 Ų49.725%0.25226%0.26SS..Hα-helixtrans-59.9-30.3172.5-52.50000112.8D109 K110 I111 K117 R157D109-S113 PolarHBondContact O-N 3.01Å; D109-S113 VanDerWaalsContact O-N 3.09Å; D109-S113 PolarHBondContact O-OG 3.31Å; K110-S113 WeakPolarHBondContact O-CB 3.31Å; K110-S113 PolarHBondContact O-N 2.96Å; I111-S113 PolarHBondContact O-N 3.42Å; S113-K117 WeakPolarHBondContact O-CG 3.44Å; S113-K117 PolarHBondContact O-N 3.06Å; S113-R157 PolarHBondContact OG-NH2 3.38Å
114F87.8Confident86.7Confident12 Ų1251.1 Ų51.15%0.05327%0.271CS..Hα-helixtrans-71.5-40.7170.4157.7-81.4000111.8L72 I75 Y76 I79 I111 F112 E116 K117 N118 W122L72-F114 HydrophobicContact CB-CD2 4.44Å; L72-F114 HydrophobicContact CB-CE2 4.45Å; L72-F114 HydrophobicContact CD1-CB 4.08Å; L72-F114 HydrophobicContact CD1-CD2 4.17Å; L72-F114 HydrophobicContact CD1-CG 4.3Å; L72-F114 HydrophobicContact CD2-CB 3.81Å; L72-F114 HydrophobicContact CD2-CD1 3.65Å; L72-F114 HydrophobicContact CD2-CD2 3.73Å; L72-F114 HydrophobicContact CD2-CE1 4.11Å; L72-F114 HydrophobicContact CD2-CE2 4.1Å; L72-F114 HydrophobicContact CD2-CG 3.47Å; L72-F114 VanDerWaalsContact CD2-CG 3.47Å; L72-F114 HydrophobicContact CD2-CZ 4.31Å; L72-F114 HydrophobicContact CG-CD2 4.32Å; L72-F114 HydrophobicContact CG-CG 4.42Å; I75-F114 HydrophobicContact CB-CZ 4.37Å; I75-F114 HydrophobicContact CG2-CE1 3.93Å; I75-F114 HydrophobicContact CG2-CZ 3.83Å; Y76-F114 HydrophobicContact CD1-CE2 4.26Å; Y76-F114 AromaticContact CD2-CE2 3.82Å; Y76-F114 HydrophobicContact CD2-CE2 3.82Å; Y76-F114 AromaticContact CE1-CE2 3.79Å; Y76-F114 HydrophobicContact CE1-CE2 3.79Å; Y76-F114 HydrophobicContact CE1-CZ 4.38Å; Y76-F114 AromaticContact CE2-CD2 3.95Å; Y76-F114 HydrophobicContact CE2-CD2 3.95Å; Y76-F114 AromaticContact CE2-CE2 3.35Å; Y76-F114 HydrophobicContact CE2-CE2 3.35Å; Y76-F114 HydrophobicContact CE2-CZ 4.43Å; Y76-F114 HydrophobicContact CG-CE2 4.25Å; Y76-F114 AromaticContact CZ-CD2 3.92Å; Y76-F114 AromaticContact CZ-CE2 3.3Å; I79-F114 HydrophobicContact CD1-CZ 4.49Å; I111-F114 WeakPolarHBondContact O-CA 3.37Å; I111-F114 VanDerWaalsContact O-CB 3.26Å; I111-F114 WeakPolarHBondContact O-CB 3.24Å; I111-F114 PolarHBondContact O-N 3.02Å; F112-F114 PolarHBondContact O-N 3.29Å; F114-E116 VanDerWaalsContact C-N 3.3Å; F114-E116 PolarHBondContact O-N 2.86Å; F114-K117 PolarHBondContact O-N 3.3Å; F114-N118 WeakPolarHBondContact CD2-ND2 3.35Å; F114-N118 WeakPolarHBondContact CE2-ND2 2.95Å; F114-N118 WeakPolarHBondContact CZ-ND2 3.06Å; F114-N118 PolarHBondContact O-N 3.09Å; F114-N118 VanDerWaalsContact O-N 3.17Å; F114-N118 PolarHBondContact O-ND2 2.8Å; F114-W122 HydrophobicContact CE1-CZ2 4.36Å
115V89.3Confident86.4Confident0 Ų052.1 Ų52.10%028%0.28CS..Hα-helixtrans-61.2-41.5177.5-175.10000110.7L96 I111 F112 K117 N118 W122 F161L96-V115 HydrophobicContact CD1-CG2 3.82Å; L96-V115 HydrophobicContact CD2-CG1 4.4Å; L96-V115 HydrophobicContact CD2-CG2 3.6Å; L96-V115 HydrophobicContact CG-CG2 4.26Å; I111-V115 PolarHBondContact O-N 3.15Å; F112-V115 WeakPolarHBondContact O-CA 3.39Å; F112-V115 WeakPolarHBondContact O-CB 3.34Å; F112-V115 PolarHBondContact O-N 3.01Å; V115-K117 PolarHBondContact O-N 3.25Å; V115-N118 PolarHBondContact O-N 2.93Å; V115-W122 PolarHBondContact O-NE1 3.34Å; V115-F161 HydrophobicContact CG1-CE1 4.12Å; V115-F161 HydrophobicContact CG1-CE2 3.73Å; V115-F161 HydrophobicContact CG1-CZ 3.49Å; V115-F161 VanDerWaalsContact CG1-CZ 3.49Å
116E89.2Confident86.2Confident49 Ų4953.4 Ų53.423%0.22929%0.293CS..Hα-helixtrans-62.9-37.7175.7-71.8175.2154.600113.2F112 F114 N118 V119 R157 F161F112-E116 HydrophobicContact CD1-CG 3.9Å; F112-E116 HydrophobicContact CE1-CG 3.74Å; F112-E116 WeakPolarHBondContact O-CG 3.47Å; F112-E116 PolarHBondContact O-N 3.45Å; F114-E116 VanDerWaalsContact C-N 3.3Å; F114-E116 PolarHBondContact O-N 2.86Å; E116-N118 VanDerWaalsContact C-N 3.35Å; E116-V119 WeakPolarHBondContact O-CG2 3.35Å; E116-R157 IonicContact OE1-CZ 3.36Å; E116-R157 IonicContact OE1-NE 3.74Å; E116-R157 PolarHBondContact OE1-NE 2.89Å; E116-R157 VanDerWaalsContact OE1-NE 3.11Å; E116-R157 IonicContact OE1-NH2 3.02Å; E116-R157 IonicContact OE2-CZ 2.92Å; E116-R157 IonicContact OE2-NE 2.84Å; E116-R157 IonicContact OE2-NH2 3.85Å; E116-R157 PolarHBondContact OE2-NH2 3.28Å; E116-F161 HydrophobicContact CG-CD2 4.25Å
117K89.3Confident86.3Confident166 Ų16647.4 Ų47.472%0.72226%0.261SS*.Hα-helixtrans-68.6-34.8177.6-74.7173.1-176.8178.10112.1S113 F114 V115 V119S113-K117 WeakPolarHBondContact O-CG 3.44Å; S113-K117 PolarHBondContact O-N 3.06Å; F114-K117 PolarHBondContact O-N 3.3Å; V115-K117 PolarHBondContact O-N 3.25Å; K117-V119 PolarHBondContact O-N 3.46Å
118N87.1Confident86.3Confident20 Ų2046.8 Ų46.811%0.10726%0.255CS..THydrogen-bonded Turntrans-92.117.4-173.7-68.1-37000114.6F114 V115 E116 S120 T121 W122F114-N118 WeakPolarHBondContact CD2-ND2 3.35Å; F114-N118 WeakPolarHBondContact CE2-ND2 2.95Å; F114-N118 WeakPolarHBondContact CZ-ND2 3.06Å; F114-N118 PolarHBondContact O-N 3.09Å; F114-N118 VanDerWaalsContact O-N 3.17Å; F114-N118 PolarHBondContact O-ND2 2.8Å; V115-N118 PolarHBondContact O-N 2.93Å; E116-N118 VanDerWaalsContact C-N 3.35Å; N118-S120 PolarHBondContact O-N 3.13Å; N118-S120 VanDerWaalsContact O-N 3.16Å; N118-T121 WeakPolarHBondContact O-CB 3.49Å; N118-T121 PolarHBondContact O-N 3.3Å; N118-W122 VanDerWaalsContact C-CD1 3.44Å; N118-W122 HydrophobicContact CB-CZ2 4.28Å; N118-W122 PolarHBondContact O-N 3.34Å; N118-W122 PolarHBondContact O-NE1 2.97Å
119V86.3Confident86.1Confident4 Ų452 Ų522%0.02429%0.287CS..Hα-helixtrans-52.5-38179.5171.70000113.4E116 K117 T121 W122 K123 F161 R164E116-V119 WeakPolarHBondContact O-CG2 3.35Å; K117-V119 PolarHBondContact O-N 3.46Å; V119-T121 VanDerWaalsContact C-N 3.29Å; V119-T121 PolarHBondContact O-N 2.93Å; V119-W122 PolarHBondContact O-N 3.47Å; V119-K123 HydrophobicContact CG1-CD 4.11Å; V119-K123 HydrophobicContact CG1-CG 4.28Å; V119-K123 WeakPolarHBondContact O-CB 3.46Å; V119-K123 WeakPolarHBondContact O-CG 3.31Å; V119-K123 PolarHBondContact O-N 3.02Å; V119-F161 HydrophobicContact CG2-CD2 3.84Å; V119-F161 HydrophobicContact CG2-CE2 3.51Å; V119-R164 HydrophobicContact CG1-CG 4.21Å
120S85.3Confident85.9Confident91 Ų9150.9 Ų50.964%0.63629%0.286SS*.Hα-helixtrans-61.3-38.1177.848.90000112.5N118 S124N118-S120 PolarHBondContact O-N 3.13Å; N118-S120 VanDerWaalsContact O-N 3.16Å; S120-S124 PolarHBondContact O-N 3.47Å
121T84.8Confident85.8Confident38 Ų3844.6 Ų44.623%0.23326%0.259CS..Hα-helixtrans-68.6-45.1178.4-50.50000110.4I79 N118 V119 K123 S124 F127I79-T121 HydrophobicContact CG2-CG2 3.88Å; N118-T121 WeakPolarHBondContact O-CB 3.49Å; N118-T121 PolarHBondContact O-N 3.3Å; V119-T121 VanDerWaalsContact C-N 3.29Å; V119-T121 PolarHBondContact O-N 2.93Å; T121-K123 VanDerWaalsContact C-N 3.27Å; T121-K123 PolarHBondContact O-N 3.3Å; T121-S124 WeakPolarHBondContact O-CB 3.29Å; T121-S124 PolarHBondContact O-N 3.33Å; T121-S124 VanDerWaalsContact O-N 3.16Å; T121-S124 PolarHBondContact O-OG 3.33Å; T121-F127 HydrophobicContact CG2-CD2 4.15Å; T121-F127 HydrophobicContact CG2-CE2 4.08Å
122W85.8Confident85.6Confident1 Ų147.2 Ų47.20%0.00427%0.27CS..Hα-helixtrans-65.8-27.7178.8-50.1133.4000113.5I79 P92 F93 F114 V115 N118 V119 Y128 L135 L165I79-W122 HydrophobicContact CD1-CH2 3.72Å; I79-W122 HydrophobicContact CD1-CZ2 4.28Å; I79-W122 HydrophobicContact CD1-CZ3 4.29Å; I79-W122 HydrophobicContact CG1-CH2 4.19Å; I79-W122 HydrophobicContact CG1-CZ3 4.4Å; P92-W122 HydrophobicContact CB-CH2 4.38Å; P92-W122 HydrophobicContact CB-CZ3 4.28Å; F93-W122 HydrophobicContact CD1-CE3 4.28Å; F93-W122 HydrophobicContact CD1-CZ3 4.15Å; F93-W122 HydrophobicContact CE1-CD2 4Å; F93-W122 AromaticContact CE1-CE3 3.26Å; F93-W122 HydrophobicContact CE1-CE3 3.26Å; F93-W122 HydrophobicContact CE1-CH2 4.43Å; F93-W122 AromaticContact CE1-CZ3 3.51Å; F93-W122 HydrophobicContact CE1-CZ3 3.51Å; F93-W122 HydrophobicContact CZ-CD2 4.48Å; F93-W122 AromaticContact CZ-CE3 3.46Å; F93-W122 HydrophobicContact CZ-CE3 3.46Å; F93-W122 VanDerWaalsContact CZ-CE3 3.46Å; F93-W122 AromaticContact CZ-CZ3 3.75Å; F93-W122 HydrophobicContact CZ-CZ3 3.75Å; F114-W122 HydrophobicContact CE1-CZ2 4.36Å; V115-W122 PolarHBondContact O-NE1 3.34Å; N118-W122 VanDerWaalsContact C-CD1 3.44Å; N118-W122 HydrophobicContact CB-CZ2 4.28Å; N118-W122 PolarHBondContact O-N 3.34Å; N118-W122 PolarHBondContact O-NE1 2.97Å; V119-W122 PolarHBondContact O-N 3.47Å; W122-Y128 WeakPolarHBondContact O-CA 3.36Å; W122-Y128 PolarHBondContact O-N 2.64Å; W122-L135 HydrophobicContact CB-CD1 4.2Å; W122-L135 HydrophobicContact CG-CD1 4.4Å; W122-L165 HydrophobicContact CB-CD1 4.22Å
123K84.4Confident85.5Confident102 Ų10250.8 Ų50.844%0.44329%0.289SS..THydrogen-bonded Turntrans-81.9-9.4176-77.5-169.2174.1-163.40114.6V119 T121 R164V119-K123 HydrophobicContact CG1-CD 4.11Å; V119-K123 HydrophobicContact CG1-CG 4.28Å; V119-K123 WeakPolarHBondContact O-CB 3.46Å; V119-K123 WeakPolarHBondContact O-CG 3.31Å; V119-K123 PolarHBondContact O-N 3.02Å; T121-K123 VanDerWaalsContact C-N 3.27Å; T121-K123 PolarHBondContact O-N 3.3Å; K123-R164 WeakPolarHBondContact CE-O 3.25Å; K123-R164 PolarHBondContact NZ-O 3.11Å
124S85.6Confident85.5Confident44 Ų4453 Ų5331%0.30829%0.293SS..SBendtrans-68.5149.9177.672.80000110.7S120 T121 S126 F127 Y128S120-S124 PolarHBondContact O-N 3.47Å; T121-S124 WeakPolarHBondContact O-CB 3.29Å; T121-S124 PolarHBondContact O-N 3.33Å; T121-S124 VanDerWaalsContact O-N 3.16Å; T121-S124 PolarHBondContact O-OG 3.33Å; S124-S126 PolarHBondContact O-N 2.94Å; S124-F127 PolarHBondContact O-N 2.91Å; S124-F127 WeakPolarHBondContact OG-CD2 3.21Å; S124-Y128 WeakPolarHBondContact O-CB 3.41Å; S124-Y128 PolarHBondContact O-N 3.5Å
125S80.6Confident85.6Confident103 Ų10352.6 Ų52.672%0.7229%0.291SS*.Hα-helixtrans-59.6-32.8-172.764.50000113F127S125-F127 VanDerWaalsContact C-N 3.29Å; S125-F127 PolarHBondContact O-N 3.42Å
126S79.2Confident85.6Confident79 Ų7954.5 Ų54.555%0.55230%0.301SS*.Hα-helixtrans-63.6-32.4178.2-53.50000113.2S124S124-S126 PolarHBondContact O-N 2.94Å
127F84Confident85.6Confident3 Ų358.8 Ų58.81%0.01332%0.315CS..Hα-helixtrans-105.1-30.7-175.6-71.2-70.7000113.1I79 V82 T83 P92 F93 T121 S124 S125 G131I79-F127 HydrophobicContact CG2-CE2 4.42Å; I79-F127 HydrophobicContact CG2-CZ 4.07Å; V82-F127 HydrophobicContact CB-CE1 3.72Å; V82-F127 HydrophobicContact CB-CZ 3.71Å; V82-F127 HydrophobicContact CG1-CD1 4.29Å; V82-F127 HydrophobicContact CG1-CE1 3.35Å; V82-F127 HydrophobicContact CG1-CE2 4.46Å; V82-F127 HydrophobicContact CG1-CZ 3.46Å; V82-F127 VanDerWaalsContact CG1-CZ 3.46Å; V82-F127 HydrophobicContact CG2-CE1 4.2Å; T83-F127 HydrophobicContact CG2-CE2 4.12Å; T83-F127 HydrophobicContact CG2-CZ 4.28Å; P92-F127 HydrophobicContact CG-CE1 4.21Å; F93-F127 HydrophobicContact CE2-CB 4.37Å; F93-F127 HydrophobicContact CE2-CD1 4.07Å; F93-F127 HydrophobicContact CZ-CB 4.05Å; F93-F127 HydrophobicContact CZ-CD1 4.3Å; T121-F127 HydrophobicContact CG2-CD2 4.15Å; T121-F127 HydrophobicContact CG2-CE2 4.08Å; S124-F127 PolarHBondContact O-N 2.91Å; S124-F127 WeakPolarHBondContact OG-CD2 3.21Å; S125-F127 VanDerWaalsContact C-N 3.29Å; S125-F127 PolarHBondContact O-N 3.42Å; F127-G131 WeakPolarHBondContact O-CA 3.27Å; F127-G131 PolarHBondContact O-N 3.15Å
128Y84.6Confident85.7Confident43 Ų4351.4 Ų51.417%0.16928%0.283CS..Hα-helixtrans-62.6-52.5-171.7-171.5-103.4000112.7W122 S124 A130 G131 K132 P167 E170W122-Y128 WeakPolarHBondContact O-CA 3.36Å; W122-Y128 PolarHBondContact O-N 2.64Å; S124-Y128 WeakPolarHBondContact O-CB 3.41Å; S124-Y128 PolarHBondContact O-N 3.5Å; Y128-A130 VanDerWaalsContact C-N 3.35Å; Y128-A130 PolarHBondContact O-N 3.36Å; Y128-G131 PolarHBondContact O-N 2.71Å; Y128-K132 HydrophobicContact CE1-CD 4.14Å; Y128-K132 VanDerWaalsContact O-CB 3.26Å; Y128-K132 WeakPolarHBondContact O-CB 3.41Å; Y128-K132 WeakPolarHBondContact O-CG 3.44Å; Y128-K132 PolarHBondContact O-N 3.32Å; Y128-P167 WeakPolarHBondContact OH-CD 3.06Å; Y128-E170 PolarHBondContact OH-OE2 3.25Å
129T83.9Confident85.9Confident111 Ų11150.4 Ų50.468%0.68128%0.278SS*.Hα-helixtrans-64.4-40.2-175.8-54.60000111.9
130A82.6Confident86.1Confident33 Ų3353.3 Ų53.327%0.27329%0.293SS..Hα-helixtrans-78.1-33.7-179.700000112.8A89 T90 Y128 Y134A89-A130 HydrophobicContact CB-CB 3.86Å; T90-A130 HydrophobicContact CG2-CB 4.22Å; Y128-A130 VanDerWaalsContact C-N 3.35Å; Y128-A130 PolarHBondContact O-N 3.36Å; A130-Y134 WeakPolarHBondContact O-CD2 3.35Å; A130-Y134 WeakPolarHBondContact O-CE2 3.18Å
131G83Confident86.3Confident1 Ų151.6 Ų51.61%0.0128%0.277CS..Hα-helixtrans-97.1-24.6-167.700000116.6F93 F127 Y128 N133 Y134 L135F93-G131 VanDerWaalsContact CD2-CA 3.44Å; F93-G131 VanDerWaalsContact CZ-CA 3.47Å; F127-G131 WeakPolarHBondContact O-CA 3.27Å; F127-G131 PolarHBondContact O-N 3.15Å; Y128-G131 PolarHBondContact O-N 2.71Å; G131-N133 VanDerWaalsContact C-N 3.29Å; G131-N133 PolarHBondContact O-N 3.01Å; G131-N133 VanDerWaalsContact O-N 3.15Å; G131-Y134 WeakPolarHBondContact O-CB 3.16Å; G131-Y134 PolarHBondContact O-N 3.48Å; G131-L135 PolarHBondContact O-N 2.87Å
132K85.3Confident86.5Confident56 Ų5649.8 Ų49.824%0.24327%0.266CS..Hα-helixtrans-56.1-39.1-169.466.5179.7-166.3160.70114.7Y128 L136 F166 E170Y128-K132 HydrophobicContact CE1-CD 4.14Å; Y128-K132 VanDerWaalsContact O-CB 3.26Å; Y128-K132 WeakPolarHBondContact O-CB 3.41Å; Y128-K132 WeakPolarHBondContact O-CG 3.44Å; Y128-K132 PolarHBondContact O-N 3.32Å; K132-L136 WeakPolarHBondContact O-CB 3.35Å; K132-L136 PolarHBondContact O-N 3.48Å; K132-F166 HydrophobicContact CB-CE1 4.06Å; K132-E170 IonicContact NZ-OE1 3.03Å; K132-E170 PolarHBondContact NZ-OE1 2.89Å
133N88.4Confident86.6Confident74 Ų7451.5 Ų51.540%0.39628%0.275SS..Hα-helixtrans-73-32.3179.2-71.3-35.1000112.2G131 R137G131-N133 VanDerWaalsContact C-N 3.29Å; G131-N133 PolarHBondContact O-N 3.01Å; G131-N133 VanDerWaalsContact O-N 3.15Å; N133-R137 VanDerWaalsContact O-CG 3.32Å; N133-R137 WeakPolarHBondContact O-CG 3.26Å; N133-R137 PolarHBondContact O-N 3.41Å
134Y89.3Confident86.7Confident84 Ų8456.3 Ų56.333%0.32929%0.29SS..Hα-helixtrans-69.6-44.7175.4-68.2-78.1000110.8T90 F93 V94 A130 G131 L136 R137 M138T90-Y134 HydrophobicContact CG2-CE2 3.87Å; F93-Y134 HydrophobicContact CB-CD2 4.3Å; F93-Y134 HydrophobicContact CB-CG 4.03Å; V94-Y134 HydrophobicContact CG2-CD1 4.38Å; V94-Y134 HydrophobicContact CG2-CE1 4Å; A130-Y134 WeakPolarHBondContact O-CD2 3.35Å; A130-Y134 WeakPolarHBondContact O-CE2 3.18Å; G131-Y134 WeakPolarHBondContact O-CB 3.16Å; G131-Y134 PolarHBondContact O-N 3.48Å; Y134-L136 VanDerWaalsContact C-N 3.31Å; Y134-L136 PolarHBondContact O-N 3.32Å; Y134-R137 PolarHBondContact O-N 2.76Å; Y134-M138 VanDerWaalsContact O-CB 3.25Å; Y134-M138 WeakPolarHBondContact O-CB 3.4Å; Y134-M138 PolarHBondContact O-N 3.14Å
135L89.7Confident86.8Confident2 Ų258.6 Ų58.61%0.0129%0.292CS..Hα-helixtrans-59.2-42.8174.4-69.6176.6000111.7F93 W122 G131 M138 C139 F161 L165F93-L135 HydrophobicContact CD1-CD1 4.35Å; F93-L135 HydrophobicContact CD1-CD2 3.82Å; F93-L135 HydrophobicContact CD1-CG 3.79Å; F93-L135 HydrophobicContact CE1-CD1 3.81Å; F93-L135 HydrophobicContact CE1-CD2 4Å; F93-L135 HydrophobicContact CE1-CG 3.77Å; W122-L135 HydrophobicContact CB-CD1 4.2Å; W122-L135 HydrophobicContact CG-CD1 4.4Å; G131-L135 PolarHBondContact O-N 2.87Å; L135-M138 HydrophobicContact CD2-CE 3.53Å; L135-C139 WeakPolarHBondContact O-CB 3.39Å; L135-C139 PolarHBondContact O-N 3.45Å; L135-C139 PolarHBondContact O-SG 3.29Å; L135-F161 HydrophobicContact CD1-CZ 4.48Å; L135-L165 HydrophobicContact CB-CD2 3.87Å; L135-L165 HydrophobicContact CD1-CD1 3.91Å; L135-L165 HydrophobicContact CD1-CD2 3.52Å; L135-L165 HydrophobicContact CD1-CG 4.38Å; L135-L165 HydrophobicContact CG-CD2 4.36Å
136L89.6Confident87Confident41 Ų4154 Ų5422%0.21526%0.26CS..Hα-helixtrans-59.8-49175.6-171.782.1000111.9K132 Y134 C139 N140 L162 F166K132-L136 WeakPolarHBondContact O-CB 3.35Å; K132-L136 PolarHBondContact O-N 3.48Å; Y134-L136 VanDerWaalsContact C-N 3.31Å; Y134-L136 PolarHBondContact O-N 3.32Å; L136-C139 PolarHBondContact O-N 2.97Å; L136-N140 WeakPolarHBondContact O-CB 3.44Å; L136-N140 VanDerWaalsContact O-CG 3.25Å; L136-N140 PolarHBondContact O-N 2.76Å; L136-N140 PolarHBondContact O-ND2 2.9Å; L136-L162 HydrophobicContact CD1-CD2 4.37Å; L136-F166 HydrophobicContact CB-CZ 4.21Å; L136-F166 HydrophobicContact CD1-CE2 3.62Å; L136-F166 HydrophobicContact CD1-CZ 3.89Å
137R89.8Confident86.9Confident139 Ų13952.5 Ų52.553%0.52525%0.249SC..Hα-helixtrans-61.5-51.6179.6-74.1176.8-168136.6-0.1111.3N133 Y134 C139 N140 D141N133-R137 VanDerWaalsContact O-CG 3.32Å; N133-R137 WeakPolarHBondContact O-CG 3.26Å; N133-R137 PolarHBondContact O-N 3.41Å; Y134-R137 PolarHBondContact O-N 2.76Å; R137-C139 VanDerWaalsContact C-N 3.31Å; R137-C139 PolarHBondContact O-N 3.46Å; R137-N140 CarbonylContact O-C 3.59Å; R137-N140 WeakPolarHBondContact O-CA 3.23Å; R137-N140 WeakPolarHBondContact O-CB 3.47Å; R137-N140 PolarHBondContact O-N 3.25Å; R137-D141 WeakPolarHBondContact O-CB 3.45Å; R137-D141 VanDerWaalsContact O-CG 3.28Å; R137-D141 PolarHBondContact O-N 2.95Å
138M91Very high86.3Confident10 Ų1059.5 Ų59.55%0.04928%0.279CS..Hα-helixtrans-55.4-44.5178.4-178.1-176.377.900112.3L96 L100 Y134 L135 D141 L142L96-M138 HydrophobicContact CB-SD 4.32Å; L96-M138 HydrophobicContact CD2-CE 3.66Å; L96-M138 HydrophobicContact CD2-SD 3.58Å; L96-M138 VanDerWaalsContact CD2-SD 3.58Å; L96-M138 HydrophobicContact CG-CE 4.33Å; L96-M138 HydrophobicContact CG-SD 3.65Å; L100-M138 HydrophobicContact CD1-CE 4.14Å; L100-M138 HydrophobicContact CD1-CG 3.48Å; L100-M138 VanDerWaalsContact CD1-CG 3.48Å; L100-M138 HydrophobicContact CD1-SD 3.35Å; L100-M138 WeakPolarHBondContact CD1-SD 3.33Å; Y134-M138 VanDerWaalsContact O-CB 3.25Å; Y134-M138 WeakPolarHBondContact O-CB 3.4Å; Y134-M138 PolarHBondContact O-N 3.14Å; L135-M138 HydrophobicContact CD2-CE 3.53Å; M138-D141 PolarHBondContact O-N 3Å; M138-L142 WeakPolarHBondContact O-CB 3.25Å; M138-L142 WeakPolarHBondContact O-CG 3.37Å; M138-L142 PolarHBondContact O-N 3.44Å
139C90.9Very high85.5Confident0 Ų061.9 Ų61.90%030%0.302CS..Hα-helixtrans-66.5-40.5176-66.70000112.2L135 L136 R137 L142 L143 I158 L162L135-C139 WeakPolarHBondContact O-CB 3.39Å; L135-C139 PolarHBondContact O-N 3.45Å; L135-C139 PolarHBondContact O-SG 3.29Å; L136-C139 PolarHBondContact O-N 2.97Å; R137-C139 VanDerWaalsContact C-N 3.31Å; R137-C139 PolarHBondContact O-N 3.46Å; C139-L142 PolarHBondContact O-N 3.14Å; C139-L143 WeakPolarHBondContact O-CB 3.33Å; C139-L143 VanDerWaalsContact O-CG 3.27Å; C139-L143 WeakPolarHBondContact O-CG 3.26Å; C139-L143 PolarHBondContact O-N 2.97Å; C139-I158 HydrophobicContact CB-CG2 3.6Å; C139-L162 HydrophobicContact CB-CD1 3.76Å; C139-L162 HydrophobicContact CB-CD2 3.76Å; C139-L162 HydrophobicContact CB-CG 3.93Å
140N89.5Confident85Confident64 Ų6464.2 Ų64.234%0.34231%0.305SS..Hα-helixtrans-66.4-37.7176.7-74.5-27.6000112.4L136 R137 L143 R144L136-N140 WeakPolarHBondContact O-CB 3.44Å; L136-N140 VanDerWaalsContact O-CG 3.25Å; L136-N140 PolarHBondContact O-N 2.76Å; L136-N140 PolarHBondContact O-ND2 2.9Å; R137-N140 CarbonylContact O-C 3.59Å; R137-N140 WeakPolarHBondContact O-CA 3.23Å; R137-N140 WeakPolarHBondContact O-CB 3.47Å; R137-N140 PolarHBondContact O-N 3.25Å; N140-L143 PolarHBondContact O-N 3.34Å; N140-R144 VanDerWaalsContact O-CG 3.31Å; N140-R144 WeakPolarHBondContact O-CG 3.47Å; N140-R144 PolarHBondContact O-N 3.24Å
141D89.8Confident84.8Confident55 Ų5565 Ų6529%0.29431%0.305SS..Hα-helixtrans-70.1-39.1177.9-66.4-31.5000110.8R137 M138 R144 R145R137-D141 WeakPolarHBondContact O-CB 3.45Å; R137-D141 VanDerWaalsContact O-CG 3.28Å; R137-D141 PolarHBondContact O-N 2.95Å; M138-D141 PolarHBondContact O-N 3Å; D141-R144 PolarHBondContact O-N 2.93Å; D141-R144 IonicContact OD1-NH1 2.64Å; D141-R145 WeakPolarHBondContact O-CG 3.41Å; D141-R145 PolarHBondContact O-N 2.93Å
142L89.3Confident84.9Confident1 Ų168 Ų681%0.00532%0.323CS..Hα-helixtrans-59.5-48.8168-74176.1000111.6L100 C108 F112 M138 C139 R144 R145 L146 I158L100-L142 HydrophobicContact CD1-CD1 4.2Å; C108-L142 HydrophobicContact CB-CD2 4.28Å; F112-L142 HydrophobicContact CD2-CD1 4.1Å; F112-L142 HydrophobicContact CE2-CD1 4.43Å; M138-L142 WeakPolarHBondContact O-CB 3.25Å; M138-L142 WeakPolarHBondContact O-CG 3.37Å; M138-L142 PolarHBondContact O-N 3.44Å; C139-L142 PolarHBondContact O-N 3.14Å; L142-R144 PolarHBondContact O-N 3.41Å; L142-R145 PolarHBondContact O-N 3Å; L142-R145 VanDerWaalsContact O-N 3.08Å; L142-L146 WeakPolarHBondContact O-CB 3.37Å; L142-L146 WeakPolarHBondContact O-CG 3.36Å; L142-L146 PolarHBondContact O-N 3.41Å; L142-I158 HydrophobicContact CB-CD1 3.82Å; L142-I158 HydrophobicContact CD1-CD1 4.14Å
143L88.3Confident84.9Confident36 Ų3670.7 Ų70.719%0.18834%0.344CS..Hα-helixtrans-61.2-28178.2-73.2172000113.3C139 N140 C155 I158 Q159C139-L143 WeakPolarHBondContact O-CB 3.33Å; C139-L143 VanDerWaalsContact O-CG 3.27Å; C139-L143 WeakPolarHBondContact O-CG 3.26Å; C139-L143 PolarHBondContact O-N 2.97Å; N140-L143 PolarHBondContact O-N 3.34Å; L143-C155 HydrophobicContact CD2-CB 3.9Å; L143-I158 HydrophobicContact CD1-CG2 4.2Å; L143-I158 HydrophobicContact CD2-CB 4.34Å; L143-I158 HydrophobicContact CD2-CD1 4.41Å; L143-I158 HydrophobicContact CD2-CG2 4.29Å; L143-I158 HydrophobicContact CG-CG2 4.01Å; L143-Q159 HydrophobicContact CD1-CG 4.47Å
144R87.4Confident84.9Confident203 Ų20367.9 Ų67.977%0.76633%0.328SS*.Hα-helixtrans-77.4-34.8174-74.9170.6178-177.4-2.8112.8N140 D141 L142N140-R144 VanDerWaalsContact O-CG 3.31Å; N140-R144 WeakPolarHBondContact O-CG 3.47Å; N140-R144 PolarHBondContact O-N 3.24Å; D141-R144 PolarHBondContact O-N 2.93Å; D141-R144 IonicContact OD1-NH1 2.64Å; L142-R144 PolarHBondContact O-N 3.41Å
145R86.4Confident84.8Confident92 Ų9264.6 Ų64.635%0.34732%0.318SS..Hα-helixtrans-78-27.6178.5-72.4170.863.7-157.8-1112.8L100 D101 L103 L105 D141 L142L100-R145 PolarHBondContact O-NH1 3.06Å; L100-R145 PolarHBondContact O-NH2 3.48Å; D101-R145 IonicContact OD1-NH1 3.46Å; L103-R145 PolarHBondContact O-NH2 3.35Å; L105-R145 HydrophobicContact CD2-CB 4.48Å; D141-R145 WeakPolarHBondContact O-CG 3.41Å; D141-R145 PolarHBondContact O-N 2.93Å; L142-R145 PolarHBondContact O-N 3Å; L142-R145 VanDerWaalsContact O-N 3.08Å
146L85.2Confident84.8Confident8 Ų865.8 Ų65.84%0.04233%0.33CS..SBendtrans-75.6136.3-178-71.2167.8000112.3L105 L142 K148 N151 F154 I158L105-L146 HydrophobicContact CD1-CD2 4.05Å; L105-L146 HydrophobicContact CD2-CD2 3.7Å; L105-L146 HydrophobicContact CD2-CG 4.4Å; L105-L146 HydrophobicContact CG-CD2 4.32Å; L142-L146 WeakPolarHBondContact O-CB 3.37Å; L142-L146 WeakPolarHBondContact O-CG 3.36Å; L142-L146 PolarHBondContact O-N 3.41Å; L146-K148 PolarHBondContact O-N 3.2Å; L146-N151 HydrophobicContact CB-CB 4.48Å; L146-N151 HydrophobicContact CD2-CB 3.85Å; L146-F154 HydrophobicContact CD1-CD1 3.41Å; L146-F154 VanDerWaalsContact CD1-CD1 3.41Å; L146-F154 HydrophobicContact CD1-CE1 3.73Å; L146-F154 HydrophobicContact CD1-CG 4.25Å; L146-F154 HydrophobicContact CD2-CD1 3.49Å; L146-F154 VanDerWaalsContact CD2-CD1 3.49Å; L146-F154 HydrophobicContact CD2-CE1 3.9Å; L146-F154 HydrophobicContact CG-CD1 4.08Å; L146-F154 HydrophobicContact CG-CE1 4.34Å; L146-I158 HydrophobicContact CD1-CD1 3.53Å
147S77.1Confident84.9Confident47 Ų4766.7 Ų66.733%0.32933%0.331SS..  trans-68127.6167.3178.50000110.4S149 N151S147-S149 PolarHBondContact O-N 3.02Å; S147-S149 PolarHBondContact OG-N 2.96Å; S147-S149 PolarHBondContact OG-OG 3.17Å; S147-N151 PolarHBondContact O-N 3Å
148K70.3Confident85Confident150 Ų15060.1 Ų60.165%0.65231%0.306SS*.THydrogen-bonded Turntrans-74.4-3.6178.1-62.9-179.1-177.5174.60113.6L146 T152L146-K148 PolarHBondContact O-N 3.2Å; K148-T152 VanDerWaalsContact O-CG2 3.29Å; K148-T152 WeakPolarHBondContact O-CG2 3.31Å
149S68.6Low84.9Confident92 Ų9265.1 Ų65.164%0.64333%0.329SS*.THydrogen-bonded Turntrans-100.9-41.7178.656.10000113.4S147S147-S149 PolarHBondContact O-N 3.02Å; S147-S149 PolarHBondContact OG-N 2.96Å; S147-S149 PolarHBondContact OG-OG 3.17Å
150Q72.8Confident84.9Confident161 Ų16171.1 Ų71.175%0.75236%0.36SS*.THydrogen-bonded Turntrans-97-36.3-175.1-68.9173.6-10.100112.9T152Q150-T152 PolarHBondContact O-N 3.12Å
151N80.1Confident85Confident48 Ų4868.3 Ų68.326%0.25735%0.345SS..  trans-103.935.1-171.4-63.4-30.7000112.9L146 S147 V153 F154 C155L146-N151 HydrophobicContact CB-CB 4.48Å; L146-N151 HydrophobicContact CD2-CB 3.85Å; S147-N151 PolarHBondContact O-N 3Å; N151-V153 VanDerWaalsContact C-N 3.32Å; N151-V153 PolarHBondContact O-N 3.21Å; N151-F154 PolarHBondContact O-N 3.22Å; N151-C155 PolarHBondContact O-N 2.94Å; N151-C155 PolarHBondContact O-SG 3.33Å; N151-C155 VanDerWaalsContact O-SG 3.34Å
152T83.4Confident84.9Confident66 Ų6666.8 Ų66.841%0.40534%0.337SS..Hα-helixtrans-61.6-38.9-176.854.30000112.4K148 Q150 C155 G156K148-T152 VanDerWaalsContact O-CG2 3.29Å; K148-T152 WeakPolarHBondContact O-CG2 3.31Å; Q150-T152 PolarHBondContact O-N 3.12Å; T152-C155 PolarHBondContact O-N 3.37Å; T152-G156 PolarHBondContact O-N 3.25Å
153V86.8Confident84.8Confident112 Ų11270.1 Ų70.168%0.67937%0.365SS*.Hα-helixtrans-62.4-45.1177.2179.50000111N151 G156 R157N151-V153 VanDerWaalsContact C-N 3.32Å; N151-V153 PolarHBondContact O-N 3.21Å; V153-G156 PolarHBondContact O-N 3.34Å; V153-R157 PolarHBondContact O-N 3.03Å
154F87.6Confident84.7Confident14 Ų1475.9 Ų75.96%0.06138%0.384CS..Hα-helixtrans-69.2-40.5179.5-174.7-137.9000111.9D109 F112 L146 N151 G156 R157 I158D109-F154 HydrophobicContact CB-CD2 4.44Å; D109-F154 HydrophobicContact CB-CE2 4.29Å; D109-F154 HydrophobicContact CB-CZ 4.39Å; D109-F154 WeakPolarHBondContact OD1-CD2 3.35Å; F112-F154 HydrophobicContact CB-CE2 3.61Å; F112-F154 HydrophobicContact CB-CZ 3.88Å; F112-F154 AromaticContact CD1-CE2 3.8Å; F112-F154 HydrophobicContact CD1-CE2 3.8Å; F112-F154 HydrophobicContact CD2-CE2 4.5Å; F112-F154 AromaticContact CG-CE2 3.7Å; F112-F154 HydrophobicContact CG-CE2 3.7Å; F112-F154 HydrophobicContact CG-CZ 4.12Å; L146-F154 HydrophobicContact CD1-CD1 3.41Å; L146-F154 VanDerWaalsContact CD1-CD1 3.41Å; L146-F154 HydrophobicContact CD1-CE1 3.73Å; L146-F154 HydrophobicContact CD1-CG 4.25Å; L146-F154 HydrophobicContact CD2-CD1 3.49Å; L146-F154 VanDerWaalsContact CD2-CD1 3.49Å; L146-F154 HydrophobicContact CD2-CE1 3.9Å; L146-F154 HydrophobicContact CG-CD1 4.08Å; L146-F154 HydrophobicContact CG-CE1 4.34Å; N151-F154 PolarHBondContact O-N 3.22Å; F154-G156 VanDerWaalsContact C-N 3.29Å; F154-G156 PolarHBondContact O-N 2.91Å; F154-R157 WeakPolarHBondContact O-CB 3.42Å; F154-R157 PolarHBondContact O-N 3.11Å; F154-I158 HydrophobicContact CD1-CD1 4.31Å; F154-I158 HydrophobicContact CD2-CD1 4.46Å; F154-I158 HydrophobicContact CD2-CG1 4.45Å; F154-I158 HydrophobicContact CE1-CD1 4.04Å; F154-I158 HydrophobicContact CE2-CD1 4.19Å; F154-I158 HydrophobicContact CE2-CG1 4.16Å; F154-I158 HydrophobicContact CG-CD1 4.5Å; F154-I158 HydrophobicContact CZ-CD1 3.97Å; F154-I158 HydrophobicContact CZ-CG1 4.36Å; F154-I158 WeakPolarHBondContact O-CG1 3.47Å; F154-I158 PolarHBondContact O-N 2.96Å
155C88.3Confident84.6Confident16 Ų1666.3 Ų66.311%0.10835%0.348CS..Hα-helixtrans-56.1-43.3169.8-70.70000112.1L143 N151 T152 I158 Q159L143-C155 HydrophobicContact CD2-CB 3.9Å; N151-C155 PolarHBondContact O-N 2.94Å; N151-C155 PolarHBondContact O-SG 3.33Å; N151-C155 VanDerWaalsContact O-SG 3.34Å; T152-C155 PolarHBondContact O-N 3.37Å; C155-I158 PolarHBondContact O-N 3.34Å; C155-Q159 WeakPolarHBondContact O-CG 3.19Å; C155-Q159 PolarHBondContact O-N 3.07Å
156G89.4Confident84.4Confident26 Ų2662.6 Ų62.627%0.26833%0.334SS..Hα-helixtrans-62.6-43.3176.500000112.6T152 V153 F154 I158 Q159 L160T152-G156 PolarHBondContact O-N 3.25Å; V153-G156 PolarHBondContact O-N 3.34Å; F154-G156 VanDerWaalsContact C-N 3.29Å; F154-G156 PolarHBondContact O-N 2.91Å; G156-I158 PolarHBondContact O-N 2.65Å; G156-Q159 PolarHBondContact O-N 2.63Å; G156-L160 WeakPolarHBondContact O-CB 3.45Å; G156-L160 WeakPolarHBondContact O-CG 3.33Å; G156-L160 PolarHBondContact O-N 2.8Å
157R91.9Very high84.1Confident61 Ų6165 Ų6523%0.2335%0.351CS..Hα-helixtrans-59.6-43.2174.3-76.9176.361.2-161.5-2.3112.6D109 S113 E116 V153 F154 Q159 L160 F161D109-R157 IonicContact OD1-CZ 3.76Å; D109-R157 IonicContact OD1-NH1 3.89Å; D109-R157 PolarHBondContact OD1-NH1 2.8Å; D109-R157 IonicContact OD1-NH2 2.79Å; D109-R157 IonicContact OD2-NH1 3.72Å; S113-R157 PolarHBondContact OG-NH2 3.38Å; E116-R157 IonicContact OE1-CZ 3.36Å; E116-R157 IonicContact OE1-NE 3.74Å; E116-R157 PolarHBondContact OE1-NE 2.89Å; E116-R157 VanDerWaalsContact OE1-NE 3.11Å; E116-R157 IonicContact OE1-NH2 3.02Å; E116-R157 IonicContact OE2-CZ 2.92Å; E116-R157 IonicContact OE2-NE 2.84Å; E116-R157 IonicContact OE2-NH2 3.85Å; E116-R157 PolarHBondContact OE2-NH2 3.28Å; V153-R157 PolarHBondContact O-N 3.03Å; F154-R157 WeakPolarHBondContact O-CB 3.42Å; F154-R157 PolarHBondContact O-N 3.11Å; R157-Q159 PolarHBondContact O-N 3.35Å; R157-L160 PolarHBondContact O-N 3.46Å; R157-F161 WeakPolarHBondContact O-CB 3.22Å; R157-F161 PolarHBondContact O-N 3.36Å
158I91.1Very high83.8Confident0 Ų068.3 Ų68.30%036%0.364CS..Hα-helixtrans-60.9-45.2175.6-65.7165000111.1F112 C139 L142 L143 L146 F154 C155 G156 F161 L162F112-I158 HydrophobicContact CD1-CG1 4.38Å; F112-I158 HydrophobicContact CD2-CG1 4.35Å; F112-I158 HydrophobicContact CE1-CB 4.49Å; F112-I158 HydrophobicContact CE1-CG1 3.92Å; F112-I158 HydrophobicContact CE2-CG1 3.9Å; F112-I158 HydrophobicContact CZ-CB 4.09Å; F112-I158 HydrophobicContact CZ-CG1 3.68Å; F112-I158 HydrophobicContact CZ-CG2 4.38Å; C139-I158 HydrophobicContact CB-CG2 3.6Å; L142-I158 HydrophobicContact CB-CD1 3.82Å; L142-I158 HydrophobicContact CD1-CD1 4.14Å; L143-I158 HydrophobicContact CD1-CG2 4.2Å; L143-I158 HydrophobicContact CD2-CB 4.34Å; L143-I158 HydrophobicContact CD2-CD1 4.41Å; L143-I158 HydrophobicContact CD2-CG2 4.29Å; L143-I158 HydrophobicContact CG-CG2 4.01Å; L146-I158 HydrophobicContact CD1-CD1 3.53Å; F154-I158 HydrophobicContact CD1-CD1 4.31Å; F154-I158 HydrophobicContact CD2-CD1 4.46Å; F154-I158 HydrophobicContact CD2-CG1 4.45Å; F154-I158 HydrophobicContact CE1-CD1 4.04Å; F154-I158 HydrophobicContact CE2-CD1 4.19Å; F154-I158 HydrophobicContact CE2-CG1 4.16Å; F154-I158 HydrophobicContact CG-CD1 4.5Å; F154-I158 HydrophobicContact CZ-CD1 3.97Å; F154-I158 HydrophobicContact CZ-CG1 4.36Å; F154-I158 WeakPolarHBondContact O-CG1 3.47Å; F154-I158 PolarHBondContact O-N 2.96Å; C155-I158 PolarHBondContact O-N 3.34Å; G156-I158 PolarHBondContact O-N 2.65Å; I158-F161 WeakPolarHBondContact O-CB 3.34Å; I158-F161 PolarHBondContact O-N 2.92Å; I158-L162 HydrophobicContact CG2-CD1 4.35Å; I158-L162 WeakPolarHBondContact O-CG 3.49Å; I158-L162 PolarHBondContact O-N 2.76Å
159Q89.1Confident83.8Confident116 Ų11663.5 Ų63.554%0.54235%0.349SS..Hα-helixtrans-65.3-41.2178-70.5177.8-4.100112.4L143 C155 G156 R157 F161 L162 A163L143-Q159 HydrophobicContact CD1-CG 4.47Å; C155-Q159 WeakPolarHBondContact O-CG 3.19Å; C155-Q159 PolarHBondContact O-N 3.07Å; G156-Q159 PolarHBondContact O-N 2.63Å; R157-Q159 PolarHBondContact O-N 3.35Å; Q159-F161 VanDerWaalsContact C-N 3.32Å; Q159-F161 PolarHBondContact O-N 2.92Å; Q159-L162 PolarHBondContact O-N 2.99Å; Q159-A163 WeakPolarHBondContact O-CB 3.37Å; Q159-A163 PolarHBondContact O-N 3.31Å
160L90.3Very high84.2Confident125 Ų12560.4 Ų60.465%0.65433%0.325SS*.Hα-helixtrans-62.9-39174.5-73.4173.1000111.9G156 R157 A163 R164G156-L160 WeakPolarHBondContact O-CB 3.45Å; G156-L160 WeakPolarHBondContact O-CG 3.33Å; G156-L160 PolarHBondContact O-N 2.8Å; R157-L160 PolarHBondContact O-N 3.46Å; L160-A163 PolarHBondContact O-N 3.21Å; L160-R164 WeakPolarHBondContact O-CB 3.14Å; L160-R164 PolarHBondContact O-N 3.35Å
161F90.9Very high84.3Confident6 Ų660.4 Ų60.43%0.02632%0.322CS..Hα-helixtrans-62.5-46.5173.8172.7-95.7000111.6F112 V115 E116 V119 L135 R157 I158 Q159 A163 R164 L165F112-F161 HydrophobicContact CE1-CB 3.97Å; F112-F161 HydrophobicContact CE1-CG 4.36Å; F112-F161 HydrophobicContact CE2-CD1 4.4Å; F112-F161 HydrophobicContact CZ-CB 3.67Å; F112-F161 AromaticContact CZ-CD1 3.88Å; F112-F161 HydrophobicContact CZ-CD1 3.88Å; F112-F161 AromaticContact CZ-CG 3.77Å; F112-F161 HydrophobicContact CZ-CG 3.77Å; V115-F161 HydrophobicContact CG1-CE1 4.12Å; V115-F161 HydrophobicContact CG1-CE2 3.73Å; V115-F161 HydrophobicContact CG1-CZ 3.49Å; V115-F161 VanDerWaalsContact CG1-CZ 3.49Å; E116-F161 HydrophobicContact CG-CD2 4.25Å; V119-F161 HydrophobicContact CG2-CD2 3.84Å; V119-F161 HydrophobicContact CG2-CE2 3.51Å; L135-F161 HydrophobicContact CD1-CZ 4.48Å; R157-F161 WeakPolarHBondContact O-CB 3.22Å; R157-F161 PolarHBondContact O-N 3.36Å; I158-F161 WeakPolarHBondContact O-CB 3.34Å; I158-F161 PolarHBondContact O-N 2.92Å; Q159-F161 VanDerWaalsContact C-N 3.32Å; Q159-F161 PolarHBondContact O-N 2.92Å; F161-A163 PolarHBondContact O-N 3.33Å; F161-R164 CarbonylContact O-C 3.54Å; F161-R164 PolarHBondContact O-N 3.09Å; F161-R164 VanDerWaalsContact O-N 3.15Å; F161-L165 HydrophobicContact CE1-CD2 4.28Å; F161-L165 WeakPolarHBondContact O-CB 3.35Å; F161-L165 PolarHBondContact O-N 3.2Å
162L88.3Confident83.9Confident23 Ų2361.3 Ų61.312%0.1233%0.332CS..Hα-helixtrans-61-43.9176.6-71.8171.7000111.9L136 C139 I158 Q159 R164 L165 F166L136-L162 HydrophobicContact CD1-CD2 4.37Å; C139-L162 HydrophobicContact CB-CD1 3.76Å; C139-L162 HydrophobicContact CB-CD2 3.76Å; C139-L162 HydrophobicContact CB-CG 3.93Å; I158-L162 HydrophobicContact CG2-CD1 4.35Å; I158-L162 WeakPolarHBondContact O-CG 3.49Å; I158-L162 PolarHBondContact O-N 2.76Å; Q159-L162 PolarHBondContact O-N 2.99Å; L162-R164 VanDerWaalsContact C-N 3.27Å; L162-R164 PolarHBondContact O-N 3.33Å; L162-L165 PolarHBondContact O-N 2.65Å; L162-F166 HydrophobicContact CD2-CD2 4.48Å; L162-F166 HydrophobicContact CD2-CE2 3.84Å; L162-F166 VanDerWaalsContact O-CD2 3.31Å; L162-F166 WeakPolarHBondContact O-CD2 3.48Å; L162-F166 PolarHBondContact O-N 2.96Å
163A86.9Confident83.4Confident71 Ų7160.8 Ų60.859%0.58734%0.34SS*.Hα-helixtrans-64.1-31.8175.600000112.5Q159 L160 F161Q159-A163 WeakPolarHBondContact O-CB 3.37Å; Q159-A163 PolarHBondContact O-N 3.31Å; L160-A163 PolarHBondContact O-N 3.21Å; F161-A163 PolarHBondContact O-N 3.33Å
164R87.3Confident82.9Confident156 Ų15657.2 Ų57.259%0.58932%0.316SS*.Hα-helixtrans-75.5-35.8174.2-174.2177.4179.6177.7-1.1112V119 K123 L160 F161 L162V119-R164 HydrophobicContact CG1-CG 4.21Å; K123-R164 WeakPolarHBondContact CE-O 3.25Å; K123-R164 PolarHBondContact NZ-O 3.11Å; L160-R164 WeakPolarHBondContact O-CB 3.14Å; L160-R164 PolarHBondContact O-N 3.35Å; F161-R164 CarbonylContact O-C 3.54Å; F161-R164 PolarHBondContact O-N 3.09Å; F161-R164 VanDerWaalsContact O-N 3.15Å; L162-R164 VanDerWaalsContact C-N 3.27Å; L162-R164 PolarHBondContact O-N 3.33Å
165L84.6Confident82.7Confident2 Ų260.6 Ų60.61%0.0134%0.335CS..Hα-helixtrans-70.5-49.5-176.9-17771.1000111.2W122 L135 F161 L162W122-L165 HydrophobicContact CB-CD1 4.22Å; L135-L165 HydrophobicContact CB-CD2 3.87Å; L135-L165 HydrophobicContact CD1-CD1 3.91Å; L135-L165 HydrophobicContact CD1-CD2 3.52Å; L135-L165 HydrophobicContact CD1-CG 4.38Å; L135-L165 HydrophobicContact CG-CD2 4.36Å; F161-L165 HydrophobicContact CE1-CD2 4.28Å; F161-L165 WeakPolarHBondContact O-CB 3.35Å; F161-L165 PolarHBondContact O-N 3.2Å; L162-L165 PolarHBondContact O-N 2.65Å
166F82.8Confident82.2Confident15 Ų1561.9 Ų61.97%0.06634%0.341CS..SBendtrans-86.8131-175.3-65.6-60.2000112.1K132 L136 L162 E170K132-F166 HydrophobicContact CB-CE1 4.06Å; L136-F166 HydrophobicContact CB-CZ 4.21Å; L136-F166 HydrophobicContact CD1-CE2 3.62Å; L136-F166 HydrophobicContact CD1-CZ 3.89Å; L162-F166 HydrophobicContact CD2-CD2 4.48Å; L162-F166 HydrophobicContact CD2-CE2 3.84Å; L162-F166 VanDerWaalsContact O-CD2 3.31Å; L162-F166 WeakPolarHBondContact O-CD2 3.48Å; L162-F166 PolarHBondContact O-N 2.96Å; F166-E170 HydrophobicContact CB-CB 4.38Å; F166-E170 VanDerWaalsContact CD1-CD 3.45Å; F166-E170 HydrophobicContact CD1-CG 4.18Å; F166-E170 VanDerWaalsContact CD1-OE2 3.27Å; F166-E170 WeakPolarHBondContact CD1-OE2 3.38Å
167P78.4Confident81.5Confident59 Ų5966.3 Ų66.338%0.38336%0.355SS..  trans-57.4149.3166.3-22.632.7000111.2Y128 S169 E170Y128-P167 WeakPolarHBondContact OH-CD 3.06Å; P167-S169 PolarHBondContact O-N 2.74Å; P167-E170 WeakPolarHBondContact O-CB 3.16Å; P167-E170 PolarHBondContact O-N 3.17Å
168L71.8Confident81Confident116 Ų11664.6 Ų64.661%0.60735%0.352SS*.THydrogen-bonded Turntrans-58.5-22.2179-67.9171.5000113.8L174L168-L174 WeakPolarHBondContact O-CD1 3.33Å
169S69.3Low80.6Confident49 Ų4970.6 Ų70.634%0.34338%0.38SS..THydrogen-bonded Turntrans-86.2-6.5177.357.80000113.8P167 K171P167-S169 PolarHBondContact O-N 2.74Å; S169-K171 PolarHBondContact O-N 3.32Å
170E77.8Confident80.4Confident27 Ų2768.8 Ų68.813%0.12637%0.37CS..  trans-77.1122.6-179-175.6151.6-172.800111.1Y128 K132 F166 P167 S172 G173Y128-E170 PolarHBondContact OH-OE2 3.25Å; K132-E170 IonicContact NZ-OE1 3.03Å; K132-E170 PolarHBondContact NZ-OE1 2.89Å; F166-E170 HydrophobicContact CB-CB 4.38Å; F166-E170 VanDerWaalsContact CD1-CD 3.45Å; F166-E170 HydrophobicContact CD1-CG 4.18Å; F166-E170 VanDerWaalsContact CD1-OE2 3.27Å; F166-E170 WeakPolarHBondContact CD1-OE2 3.38Å; P167-E170 WeakPolarHBondContact O-CB 3.16Å; P167-E170 PolarHBondContact O-N 3.17Å; E170-S172 PolarHBondContact O-N 2.93Å; E170-S172 VanDerWaalsContact O-N 3.09Å; E170-G173 PolarHBondContact O-N 2.96Å
171K74.6Confident80.1Confident161 Ų16168 Ų6870%0.737%0.367SS*.G310 helixtrans-56.1-31.4-176.2-59.8-175.9179.9176.50113.4S169 G173 L174 L176S169-K171 PolarHBondContact O-N 3.32Å; K171-G173 VanDerWaalsContact C-N 3.27Å; K171-G173 PolarHBondContact O-N 3.42Å; K171-L174 PolarHBondContact O-N 3.17Å; K171-L176 HydrophobicContact CB-CD1 4.05Å; K171-L176 HydrophobicContact CD-CD1 4.33Å; K171-L176 HydrophobicContact CG-CD1 4.01Å
172S71Confident79.7Confident67 Ų6771.2 Ų71.247%0.46938%0.384SS..G310 helixtrans-66.9-25.4179.8-50.80000113.6E170E170-S172 PolarHBondContact O-N 2.93Å; E170-S172 VanDerWaalsContact O-N 3.09Å
173G72.5Confident79.1Confident55 Ų5576.3 Ų76.357%0.56741%0.412SS*.G310 helixtrans-91.9-1.8176.900000113.7E170 K171E170-G173 PolarHBondContact O-N 2.96Å; K171-G173 VanDerWaalsContact C-N 3.27Å; K171-G173 PolarHBondContact O-N 3.42Å
174L77.3Confident78.7Confident36 Ų3676.9 Ų76.919%0.18841%0.405CS..SBendtrans-115.7127.5-173.7-64.8171.5000110.6L168 K171 L176 W391 C396L168-L174 WeakPolarHBondContact O-CD1 3.33Å; K171-L174 PolarHBondContact O-N 3.17Å; L174-L176 HydrophobicContact CB-CD2 4.18Å; L174-L176 HydrophobicContact CB-CG 4.04Å; L174-L176 HydrophobicContact CD1-CD2 4.3Å; L174-L176 PolarHBondContact O-N 2.92Å; L174-W391 HydrophobicContact CD2-CH2 4.28Å; L174-W391 HydrophobicContact CD2-CZ3 4.44Å; L174-C396 HydrophobicContact CD1-CB 3.61Å
175N83.2Confident78.2Confident85 Ų8573.5 Ų73.546%0.45540%0.397SS..  trans-75.566.5168.6-178.411.7000110.3Q177 S178 Q179 K392N175-Q177 VanDerWaalsContact C-N 3.29Å; N175-Q177 PolarHBondContact O-N 3.21Å; N175-S178 PolarHBondContact O-N 3.31Å; N175-S178 PolarHBondContact OD1-N 2.94Å; N175-Q179 PolarHBondContact ND2-N 3.13Å; N175-Q179 PolarHBondContact ND2-O 3.07Å; N175-Q179 PolarHBondContact OD1-N 3.31Å; N175-K392 WeakPolarHBondContact O-CE 3.4Å; N175-K392 PolarHBondContact O-NZ 3.32Å
176L77.9Confident78Confident43 Ų4374.6 Ų74.623%0.22540%0.404CS..THydrogen-bonded Turntrans-57-42-174.5-72173.4000112.3K171 L174 S178 F338K171-L176 HydrophobicContact CB-CD1 4.05Å; K171-L176 HydrophobicContact CD-CD1 4.33Å; K171-L176 HydrophobicContact CG-CD1 4.01Å; L174-L176 HydrophobicContact CB-CD2 4.18Å; L174-L176 HydrophobicContact CB-CG 4.04Å; L174-L176 HydrophobicContact CD1-CD2 4.3Å; L174-L176 PolarHBondContact O-N 2.92Å; L176-S178 PolarHBondContact O-N 2.96Å; L176-F338 WeakPolarHBondContact O-CD2 3.15Å; L176-F338 WeakPolarHBondContact O-CE2 3.49Å
177Q75Confident77.8Confident120 Ų12079.3 Ų79.356%0.56143%0.434SS*.THydrogen-bonded Turntrans-71.5-5.6-179.9-64.4-178.911.800113.6N175 Q179N175-Q177 VanDerWaalsContact C-N 3.29Å; N175-Q177 PolarHBondContact O-N 3.21Å; Q177-Q179 HydrophobicContact CB-CG 4.01Å; Q177-Q179 PolarHBondContact O-N 3.38Å
178S80.8Confident78Confident25 Ų2577.3 Ų77.318%0.17542%0.419CS..  trans54.339.6-177.8-59.50000112.9N175 L176 K392N175-S178 PolarHBondContact O-N 3.31Å; N175-S178 PolarHBondContact OD1-N 2.94Å; L176-S178 PolarHBondContact O-N 2.96Å; S178-K392 WeakPolarHBondContact OG-CE 3.25Å; S178-K392 PolarHBondContact OG-NZ 3.4Å
179Q82.1Confident78.2Confident126 Ų12673.4 Ų73.459%0.58940%0.399SS*.  trans-69.8140177.1-66.7-175.8-6.600110.7N175 Q177N175-Q179 PolarHBondContact ND2-N 3.13Å; N175-Q179 PolarHBondContact ND2-O 3.07Å; N175-Q179 PolarHBondContact OD1-N 3.31Å; Q177-Q179 HydrophobicContact CB-CG 4.01Å; Q177-Q179 PolarHBondContact O-N 3.38Å
180F85.7Confident78.3Confident77 Ų7776.9 Ų76.934%0.33841%0.408SS..  trans-83.2141.4175.5-63.7-73.5000110.9L182 P247 V248 Y331F180-L182 HydrophobicContact CB-CD2 4.21Å; F180-L182 PolarHBondContact O-N 3.15Å; F180-P247 HydrophobicContact CD1-CG 4.04Å; F180-P247 HydrophobicContact CD2-CG 4.24Å; F180-P247 HydrophobicContact CE1-CG 3.47Å; F180-P247 VanDerWaalsContact CE1-CG 3.47Å; F180-P247 HydrophobicContact CE2-CG 3.7Å; F180-P247 HydrophobicContact CG-CG 4.41Å; F180-P247 HydrophobicContact CZ-CG 3.29Å; F180-V248 HydrophobicContact CD2-CG2 4.28Å; F180-V248 HydrophobicContact CE2-CG2 3.95Å; F180-Y331 HydrophobicContact CE2-CE2 4.49Å; F180-Y331 AromaticContact CE2-CZ 3.99Å; F180-Y331 HydrophobicContact CZ-CD2 4.32Å; F180-Y331 AromaticContact CZ-CE1 3.99Å; F180-Y331 HydrophobicContact CZ-CE1 3.99Å; F180-Y331 AromaticContact CZ-CE2 3.65Å; F180-Y331 HydrophobicContact CZ-CE2 3.65Å; F180-Y331 AromaticContact CZ-CZ 3.45Å; F180-Y331 VanDerWaalsContact CZ-CZ 3.45Å
181N83Confident77.9Confident108 Ų10879.7 Ų79.758%0.57842%0.424SS*.  trans-77.891.3172.3-178.57.5000109.8D183N181-D183 VanDerWaalsContact C-N 3.27Å; N181-D183 PolarHBondContact O-N 3.49Å; N181-D183 PolarHBondContact OD1-N 3.4Å; N181-D183 VanDerWaalsContact OD1-N 3.12Å
182L83.9Confident77.2Confident75 Ų7577.5 Ų77.539%0.39342%0.416SS..THydrogen-bonded Turntrans-76.3-9.6178.4-59.1179.7000112.5F180 N184 R245 N246F180-L182 HydrophobicContact CB-CD2 4.21Å; F180-L182 PolarHBondContact O-N 3.15Å; L182-N184 VanDerWaalsContact C-N 3.29Å; L182-N184 PolarHBondContact O-N 3.27Å; L182-R245 HydrophobicContact CD2-CG 4.45Å; L182-R245 PolarHBondContact O-NE 2.93Å; L182-R245 PolarHBondContact O-NH2 2.94Å; L182-N246 HydrophobicContact CD2-CB 3.96Å
183D75.4Confident76.5Confident130 Ų13083.4 Ų83.470%0.69544%0.436SS*.THydrogen-bonded Turntrans-77.2-16-177-63.9-22.2000113.4N181 I185N181-D183 VanDerWaalsContact C-N 3.27Å; N181-D183 PolarHBondContact O-N 3.49Å; N181-D183 PolarHBondContact OD1-N 3.4Å; N181-D183 VanDerWaalsContact OD1-N 3.12Å; D183-I185 VanDerWaalsContact C-N 3.32Å; D183-I185 PolarHBondContact O-N 3.33Å
184N77.7Confident75.8Confident83 Ų8386.7 Ų86.744%0.44444%0.437SS..  trans-83.772.5-179.3-167.725.9000112.1L182 R245 K300L182-N184 VanDerWaalsContact C-N 3.29Å; L182-N184 PolarHBondContact O-N 3.27Å; N184-R245 WeakPolarHBondContact O-CD 3.41Å; N184-K300 PolarHBondContact OD1-NZ 2.88Å
185I77.6Confident74.9Confident84 Ų8485.6 Ų85.643%0.43143%0.432SS..  trans-77.5132.3-179.9-42.6-160.1000110.2D183 V187D183-I185 VanDerWaalsContact C-N 3.32Å; D183-I185 PolarHBondContact O-N 3.33Å; I185-V187 PolarHBondContact O-N 3.21Å
186T80.6Confident73.9Confident25 Ų2584.3 Ų84.315%0.15343%0.428CS..  trans-84.5107.7167.2-59.10000107.3F188 W238 Q241 T303T186-F188 WeakPolarHBondContact O-CD1 3.39Å; T186-W238 HydrophobicContact CG2-CE3 3.77Å; T186-W238 HydrophobicContact CG2-CZ3 3.97Å; T186-Q241 HydrophobicContact CG2-CG 4.12Å; T186-Q241 VanDerWaalsContact OG1-CG 3.3Å; T186-Q241 WeakPolarHBondContact OG1-CG 3.48Å; T186-T303 HydrophobicContact CG2-CG2 3.42Å; T186-T303 VanDerWaalsContact CG2-CG2 3.42Å
187V79Confident73Confident114 Ų11484.3 Ų84.369%0.69143%0.428SS*.  trans-84.7122.4-179-178.60000108.1I185 T303I185-V187 PolarHBondContact O-N 3.21Å; V187-T303 VanDerWaalsContact O-CB 3.23Å; V187-T303 WeakPolarHBondContact O-CB 3.4Å; V187-T303 WeakPolarHBondContact O-CG2 3.48Å; V187-T303 PolarHBondContact O-OG1 3.22Å
188F80.9Confident71.9Confident18 Ų1882.4 Ų82.48%0.07944%0.44CS..  trans-139.4158.7178.966.9-87.8000109.7T186 K190 Y234 W238 T303T186-F188 WeakPolarHBondContact O-CD1 3.39Å; F188-K190 HydrophobicContact CD2-CG 4.08Å; F188-K190 HydrophobicContact CE2-CD 4.45Å; F188-K190 HydrophobicContact CE2-CG 3.67Å; F188-K190 HydrophobicContact CZ-CD 4.35Å; F188-K190 HydrophobicContact CZ-CG 4.05Å; F188-K190 PolarHBondContact O-N 3.29Å; F188-Y234 HydrophobicContact CD2-CE1 4.42Å; F188-W238 HydrophobicContact CB-CB 3.95Å; F188-W238 HydrophobicContact CB-CG 4.01Å; F188-W238 HydrophobicContact CD1-CB 3.63Å; F188-W238 HydrophobicContact CD2-CB 3.62Å; F188-W238 HydrophobicContact CD2-CG 4.37Å; F188-W238 HydrophobicContact CE1-CB 3.92Å; F188-W238 HydrophobicContact CE2-CB 3.91Å; F188-W238 HydrophobicContact CG-CB 3.47Å; F188-W238 VanDerWaalsContact CG-CB 3.47Å; F188-W238 HydrophobicContact CG-CG 4.08Å; F188-W238 HydrophobicContact CZ-CB 4.04Å; F188-T303 HydrophobicContact CB-CG2 4.21Å
189N76.4Confident70.3Confident34 Ų3488.1 Ų88.118%0.18246%0.464CS..  trans-66.2123178.4-166.9-0.7000111.1N191 E194 Y234 E305N189-N191 PolarHBondContact OD1-N 3.33Å; N189-N191 PolarHBondContact OD1-O 3.5Å; N189-E194 PolarHBondContact ND2-O 3.44Å; N189-Y234 HydrophobicContact CB-CE1 4.27Å; N189-Y234 PolarHBondContact N-OH 3.02Å; N189-E305 VanDerWaalsContact CB-OE1 3.24Å; N189-E305 WeakPolarHBondContact CB-OE1 3.42Å; N189-E305 PolarHBondContact ND2-OE1 3.43Å
190K71.9Confident68.1Low121 Ų12191.2 Ų91.253%0.52648%0.476SS..  trans-106.6-9.2177.8-67.8179.9179-175.30112.3F188 Y231F188-K190 HydrophobicContact CD2-CG 4.08Å; F188-K190 HydrophobicContact CE2-CD 4.45Å; F188-K190 HydrophobicContact CE2-CG 3.67Å; F188-K190 HydrophobicContact CZ-CD 4.35Å; F188-K190 HydrophobicContact CZ-CG 4.05Å; F188-K190 PolarHBondContact O-N 3.29Å; K190-Y231 PolarHBondContact O-OH 3.38Å; K190-Y231 VanDerWaalsContact O-OH 3.1Å
191N68.9Low65.8Low86 Ų8696.4 Ų96.446%0.4650%0.501SS..  trans-95.7114-175-65.1-19.6000110.9N189 Q193 E194 Y231N189-N191 PolarHBondContact OD1-N 3.33Å; N189-N191 PolarHBondContact OD1-O 3.5Å; N191-Q193 PolarHBondContact O-N 3.48Å; N191-E194 HydrophobicContact CB-CB 4.26Å; N191-E194 HydrophobicContact CB-CG 4.36Å; N191-E194 PolarHBondContact ND2-OE2 2.75Å; N191-E194 PolarHBondContact O-N 3.41Å; N191-Y231 PolarHBondContact N-OH 3.22Å; N191-Y231 PolarHBondContact O-OH 2.98Å
192E60.5Low63.1Low115 Ų11597.7 Ų97.754%0.53751%0.512SS..G310 helixtrans-60.5-26.4175.1-77.9171.2-16300112.8Y231 R235E192-Y231 HydrophobicContact CB-CE1 4.17Å; E192-Y231 HydrophobicContact CG-CD1 3.66Å; E192-Y231 HydrophobicContact CG-CE1 3.17Å; E192-Y231 PolarHBondContact N-OH 3.16Å; E192-R235 IonicContact OE1-NH1 3.26Å; E192-R235 PolarHBondContact OE1-NH1 2.94Å
193Q55.3Low60.9Low191 Ų191101.3 Ų101.389%0.89353%0.532SS*.G310 helixtrans-79.2-21.5-177.3-65.8179.5-13.100113.8N191N191-Q193 PolarHBondContact O-N 3.48Å
194E58.5Low58.7Low125 Ų125104.1 Ų104.158%0.58454%0.541SS*.G310 helixtrans-10111.8177.9-67.4175.1152.900111.5N189 N191 T196N189-E194 PolarHBondContact ND2-O 3.44Å; N191-E194 HydrophobicContact CB-CB 4.26Å; N191-E194 HydrophobicContact CB-CG 4.36Å; N191-E194 PolarHBondContact ND2-OE2 2.75Å; N191-E194 PolarHBondContact O-N 3.41Å; E194-T196 PolarHBondContact O-N 2.65Å
195S58.2Low56.9Low12 Ų12110.1 Ų110.18%0.08456%0.564CS.*  trans-68.3133.2-177.8-174.50000111.3L197 Y231 E305S195-L197 VanDerWaalsContact C-N 3.34Å; S195-L197 PolarHBondContact OG-N 2.63Å; S195-Y231 VanDerWaalsContact OG-CD2 3.28Å; S195-Y231 WeakPolarHBondContact OG-CD2 3.44Å; S195-E305 WeakPolarHBondContact CA-OE2 3.41Å; S195-E305 PolarHBondContact OG-OE2 2.61Å
196T61.7Low54.5Low59 Ų59115 Ų11536%0.36259%0.585SS.*  trans-87.7-6.1175.158.60000112.6E194 E305E194-T196 PolarHBondContact O-N 2.65Å; T196-E305 PolarHBondContact N-OE2 2.72Å; T196-E305 PolarHBondContact OG1-OE2 2.68Å
197L59.7Low52.3Low43 Ų43122 Ų12223%0.22562%0.621CS.*SBendtrans-84.6114.4178.1-70.3162.4000109.9S195 I229 E305S195-L197 VanDerWaalsContact C-N 3.34Å; S195-L197 PolarHBondContact OG-N 2.63Å; L197-I229 HydrophobicContact CD1-CG2 4.19Å; L197-E305 HydrophobicContact CD1-CB 3.8Å; L197-E305 HydrophobicContact CD1-CG 4.17Å; L197-E305 HydrophobicContact CG-CB 3.9Å
198G52.3Low49.8Very low80 Ų80122.9 Ų122.983%0.82563%0.627SS**SBendtrans95.40.5174.700000116.4K200G198-K200 PolarHBondContact O-N 2.93Å
199Q46.2Very low47.4Very low144 Ų144131 Ų13167%0.67367%0.667SS**  trans-74.2106.9168.2-74.9-179.3-15.700109.8Q201Q199-Q201 PolarHBondContact O-N 3.01Å
200K37.9Very low45Very low192 Ų192138.6 Ų138.684%0.83570%0.702SS**  trans-61131.3157.9-80.1-177.9175.3179.80107.2G198 T202G198-K200 PolarHBondContact O-N 2.93Å; K200-T202 PolarHBondContact O-N 3.1Å
201Q35.8Very low43.1Very low186 Ų186139.3 Ų139.387%0.86972%0.716SS**  trans-44.4111170-73.8173.7-11.800109.8Q199Q199-Q201 PolarHBondContact O-N 3.01Å
202T26.1Very low41.3Very low134 Ų134144.4 Ų144.482%0.82274%0.737SS**  trans-113.9107.9148.734.10000105K200 E204K200-T202 PolarHBondContact O-N 3.1Å; T202-E204 PolarHBondContact O-N 2.9Å; T202-E204 VanDerWaalsContact O-N 3.13Å
203D37.9Very low39.9Very low151 Ų151147.8 Ų147.881%0.80775%0.752SS**  trans-50.5108174-68.9-52000110.8
204E30.6Very low38.7Very low189 Ų189142.1 Ų142.188%0.88375%0.745SS**  trans-138.5111.7148.6-70.8-164.9160.200108.4T202 E206T202-E204 PolarHBondContact O-N 2.9Å; T202-E204 VanDerWaalsContact O-N 3.13Å; E204-E206 PolarHBondContact O-N 2.89Å
205K39.4Very low37.4Very low210 Ų210145.6 Ų145.691%0.91376%0.762SS**  trans-64.8121.8173.7-72.9176171.5-177.50109.4
206E27.7Very low36.2Very low187 Ų187153.9 Ų153.987%0.87480%0.801SS**  trans-131.6122.2153.8-90-168.6155.100110.7E204 T208E204-E206 PolarHBondContact O-N 2.89Å; E206-T208 PolarHBondContact O-N 3.28Å
207D33.4Very low34.7Very low171 Ų171154.7 Ų154.791%0.91482%0.821SS**  trans-55.4110.9-175.5-74.8-44.7000112.5
208T27.6Very low33.5Very low133 Ų133161.8 Ų161.882%0.81685%0.853SS**  trans-136.7123.4155.8-26.30000108.6E206 E210E206-T208 PolarHBondContact O-N 3.28Å; T208-E210 PolarHBondContact O-N 3.3Å
209M29.7Very low32.5Very low189 Ų189165.4 Ų165.493%0.93185%0.853SS**  trans-35.7115.6-171.4-75.3172.2169.300114.8V211M209-V211 PolarHBondContact O-N 3.16Å
210E26.4Very low31.8Very low193 Ų193166 Ų16690%0.90286%0.861SS**  trans-62.6120.6169.3-66.7174.7167.300109.9T208T208-E210 PolarHBondContact O-N 3.3Å
211V32.3Very low31.6Very low135 Ų135161.6 Ų161.682%0.81886%0.861SS**  trans-85114.3157.6-178.30000105M209 E213M209-V211 PolarHBondContact O-N 3.16Å; V211-E213 PolarHBondContact O-N 2.78Å
212E29.4Very low31.5Very low193 Ų193158.3 Ų158.390%0.90286%0.856SS**  trans-38.8100.4176.7-99.4177.5147.100111.9
213E32.9Very low31.9Very low186 Ų186155.8 Ų155.887%0.86985%0.848SS**  trans-75.8114.6156.8-77.8-171.2155.700106.6V211 E215V211-E213 PolarHBondContact O-N 2.78Å; E213-E215 PolarHBondContact O-N 3.25Å
214G29.4Very low31.8Very low72 Ų72154.9 Ų154.974%0.74285%0.85SS**  trans-59.2121176.100000110.9M216G214-M216 PolarHBondContact O-N 2.89Å; G214-M216 VanDerWaalsContact O-N 3.09Å
215E31.7Very low32.2Very low199 Ų199150.3 Ų150.393%0.9384%0.838SS**  trans-51.6109.4170.6-73.8178.7146.500110.7E213E213-E215 PolarHBondContact O-N 3.25Å
216M32Very low32.6Very low186 Ų186145.6 Ų145.692%0.91683%0.832SS**  trans-91.7123.3154.2-81.8-91.1-136.600106.7G214G214-M216 PolarHBondContact O-N 2.89Å; G214-M216 VanDerWaalsContact O-N 3.09Å
217G31.1Very low33.7Very low75 Ų75139 Ų13977%0.77380%0.802SS**  trans-48137-17200000114.8D219G217-D219 PolarHBondContact O-N 3.2Å; G217-D219 VanDerWaalsContact O-N 3.09Å
218E33.5Very low34.8Very low192 Ų192136.8 Ų136.890%0.89780%0.797SS**SBendtrans-57.7100.7162.4-65.1178.4142.300109.4
219D32.7Very low36.5Very low156 Ų156131.1 Ų131.183%0.83476%0.762SS**  trans-176.790.2149.8-93.2-22.5000109.3G217G217-D219 PolarHBondContact O-N 3.2Å; G217-D219 VanDerWaalsContact O-N 3.09Å
220D31.4Very low38.4Very low157 Ų157126.1 Ų126.184%0.8474%0.739SS**  trans138.788.4157.4-84.1-23.5000109.8P222D220-P222 VanDerWaalsContact O-CD 3.32Å; D220-P222 WeakPolarHBondContact O-CD 3.33Å
221A31.9Very low40.9Very low99 Ų99117.8 Ų117.882%0.81870%0.699SS**PPolyproline II helixtrans-55.1119.7165.900000109A223A221-A223 PolarHBondContact O-N 3.09Å
222P34.8Very low43.2Very low118 Ų118114.7 Ų114.777%0.76668%0.678SS**PPolyproline II helixtrans-61.6134.1172-14.627.8000107.9D220D220-P222 VanDerWaalsContact O-CD 3.32Å; D220-P222 WeakPolarHBondContact O-CD 3.33Å
223A34Very low45.8Very low81 Ų81106.9 Ų106.967%0.66964%0.642SS**PPolyproline II helixtrans-46134174.900000110.2A221 C225A221-A223 PolarHBondContact O-N 3.09Å; A223-C225 PolarHBondContact O-N 3.11Å
224P35.4Very low48.3Very low131 Ų13198.1 Ų98.185%0.85160%0.601SS**  trans-63.1106.7-178.124-31.6000109.1S226P224-S226 PolarHBondContact O-N 3.35Å
225C40.3Very low51Low93 Ų93100 Ų10063%0.62859%0.586SS**  trans-61.9135172.5-82.20000109.7A223 I227A223-C225 PolarHBondContact O-N 3.11Å; C225-I227 PolarHBondContact O-N 3.16Å; C225-I227 VanDerWaalsContact O-N 3.08Å
226S46.1Very low53.7Low112 Ų11292.6 Ų92.678%0.78355%0.551SS**SBendtrans-86.651.6-160.8610000114.4P224P224-S226 PolarHBondContact O-N 3.35Å
227I51.5Low56.4Low47 Ų4784.1 Ų84.124%0.24151%0.509CS..  trans-130.2119.8169.9-55.6166.4000108.7C225 I229 F273C225-I227 PolarHBondContact O-N 3.16Å; C225-I227 VanDerWaalsContact O-N 3.08Å; I227-I229 VanDerWaalsContact C-N 3.32Å; I227-I229 HydrophobicContact CB-CG1 4.45Å; I227-I229 HydrophobicContact CG2-CG1 4.02Å; I227-I229 PolarHBondContact O-N 3.25Å; I227-F273 HydrophobicContact CD1-CD2 3.48Å; I227-F273 VanDerWaalsContact CD1-CD2 3.48Å; I227-F273 HydrophobicContact CD1-CE2 3.58Å; I227-F273 HydrophobicContact CD1-CG 4.35Å; I227-F273 HydrophobicContact CD1-CZ 4.49Å; I227-F273 HydrophobicContact CG1-CD2 4.31Å; I227-F273 HydrophobicContact CG1-CE2 4.3Å
228P56.9Low59.2Low125 Ų12580.6 Ų80.681%0.81247%0.472SS*.  trans-71.395.6160.329-28.5000107.1D230P228-D230 PolarHBondContact O-N 2.83Å
229I63.3Low61.9Low14 Ų1473 Ų737%0.07244%0.439CS..  trans-66109.6172.2-67.5-170.6000108.1L197 I227 M308 D309 L312L197-I229 HydrophobicContact CD1-CG2 4.19Å; I227-I229 VanDerWaalsContact C-N 3.32Å; I227-I229 HydrophobicContact CB-CG1 4.45Å; I227-I229 HydrophobicContact CG2-CG1 4.02Å; I227-I229 PolarHBondContact O-N 3.25Å; I229-M308 HydrophobicContact CD1-CB 3.64Å; I229-M308 HydrophobicContact CD1-CG 3.65Å; I229-M308 HydrophobicContact CG2-CB 4.33Å; I229-M308 HydrophobicContact CG2-CG 4.2Å; I229-D309 HydrophobicContact CD1-CB 3.9Å; I229-D309 WeakPolarHBondContact CD1-OD1 3.44Å; I229-D309 WeakPolarHBondContact CD1-OD2 3.26Å; I229-D309 WeakPolarHBondContact CG1-OD1 3.31Å; I229-L312 HydrophobicContact CD1-CD1 4.04Å
230D70Confident64.7Low84 Ų8465.8 Ų65.845%0.44940%0.4SS..  trans-75137.1170.9-173.4-3.6000109.1P228 N232 L233 Y234P228-D230 PolarHBondContact O-N 2.83Å; D230-N232 PolarHBondContact O-N 3.18Å; D230-N232 VanDerWaalsContact O-N 3.09Å; D230-N232 PolarHBondContact OD1-N 3.31Å; D230-N232 VanDerWaalsContact OD1-N 3.1Å; D230-N232 PolarHBondContact OD1-ND2 3.43Å; D230-N232 WeakPolarHBondContact OD2-CB 3.49Å; D230-N232 PolarHBondContact OD2-ND2 3.08Å; D230-L233 WeakPolarHBondContact O-CB 3.41Å; D230-L233 PolarHBondContact O-N 3.41Å; D230-Y234 PolarHBondContact O-N 3.05Å
231Y77.4Confident67.5Low18 Ų1859.1 Ų59.17%0.07136%0.364CS..Hα-helixtrans-50.6-32.2170.5177.1-93.3000111.8K190 N191 E192 S195 L233 Y234 R235K190-Y231 PolarHBondContact O-OH 3.38Å; K190-Y231 VanDerWaalsContact O-OH 3.1Å; N191-Y231 PolarHBondContact N-OH 3.22Å; N191-Y231 PolarHBondContact O-OH 2.98Å; E192-Y231 HydrophobicContact CB-CE1 4.17Å; E192-Y231 HydrophobicContact CG-CD1 3.66Å; E192-Y231 HydrophobicContact CG-CE1 3.17Å; E192-Y231 PolarHBondContact N-OH 3.16Å; S195-Y231 VanDerWaalsContact OG-CD2 3.28Å; S195-Y231 WeakPolarHBondContact OG-CD2 3.44Å; Y231-L233 VanDerWaalsContact C-N 3.35Å; Y231-L233 PolarHBondContact O-N 3.09Å; Y231-Y234 HydrophobicContact CD2-CD1 4.32Å; Y231-Y234 HydrophobicContact CE2-CD1 4.31Å; Y231-Y234 HydrophobicContact CE2-CE1 4.49Å; Y231-Y234 PolarHBondContact O-N 2.7Å; Y231-R235 HydrophobicContact CE1-CB 4.26Å; Y231-R235 WeakPolarHBondContact O-CB 3.39Å; Y231-R235 PolarHBondContact O-N 3.45Å
232N82.4Confident70.2Confident71 Ų7156 Ų5638%0.3833%0.333SS..Hα-helixtrans-60.1-40.3174.3-70.7-53.8000113.4D230 K236D230-N232 PolarHBondContact O-N 3.18Å; D230-N232 VanDerWaalsContact O-N 3.09Å; D230-N232 PolarHBondContact OD1-N 3.31Å; D230-N232 VanDerWaalsContact OD1-N 3.1Å; D230-N232 PolarHBondContact OD1-ND2 3.43Å; D230-N232 WeakPolarHBondContact OD2-CB 3.49Å; D230-N232 PolarHBondContact OD2-ND2 3.08Å; N232-K236 WeakPolarHBondContact O-CB 3.49Å; N232-K236 WeakPolarHBondContact O-CG 3.33Å; N232-K236 PolarHBondContact O-N 3.17Å
233L83Confident72.9Confident28 Ų2851.4 Ų51.415%0.14730%0.301CS..Hα-helixtrans-67.7-46.8177.8177.763.3000110.3D230 Y231 R235 K236 F237 V269D230-L233 WeakPolarHBondContact O-CB 3.41Å; D230-L233 PolarHBondContact O-N 3.41Å; Y231-L233 VanDerWaalsContact C-N 3.35Å; Y231-L233 PolarHBondContact O-N 3.09Å; L233-R235 PolarHBondContact O-N 2.94Å; L233-K236 PolarHBondContact O-N 3.07Å; L233-F237 WeakPolarHBondContact O-CB 3.27Å; L233-F237 PolarHBondContact O-N 3.35Å; L233-V269 HydrophobicContact CD1-CG2 3.94Å; L233-V269 HydrophobicContact CD2-CG1 4.45Å; L233-V269 HydrophobicContact CD2-CG2 4.14Å
234Y86Confident75.7Confident3 Ų349 Ų491%0.01228%0.276CS..Hα-helixtrans-56.8-47.9177.1166.3-90.3000111.6F188 N189 D230 Y231 F237 W238 T303 E305F188-Y234 HydrophobicContact CD2-CE1 4.42Å; N189-Y234 HydrophobicContact CB-CE1 4.27Å; N189-Y234 PolarHBondContact N-OH 3.02Å; D230-Y234 PolarHBondContact O-N 3.05Å; Y231-Y234 HydrophobicContact CD2-CD1 4.32Å; Y231-Y234 HydrophobicContact CE2-CD1 4.31Å; Y231-Y234 HydrophobicContact CE2-CE1 4.49Å; Y231-Y234 PolarHBondContact O-N 2.7Å; Y234-F237 PolarHBondContact O-N 3.16Å; Y234-W238 AromaticContact CD2-CD1 3.37Å; Y234-W238 AromaticContact CD2-NE1 3.24Å; Y234-W238 AromaticContact CE2-CD1 3.19Å; Y234-W238 HydrophobicContact CE2-CG 4.44Å; Y234-W238 AromaticContact CE2-NE1 3Å; Y234-W238 AromaticContact CG-CD1 3.86Å; Y234-W238 AromaticContact CZ-CD1 3.53Å; Y234-W238 AromaticContact CZ-NE1 3.79Å; Y234-W238 PolarHBondContact O-N 2.88Å; Y234-T303 WeakPolarHBondContact CE2-O 3.48Å; Y234-T303 PolarHBondContact OH-O 3.06Å; Y234-E305 HydrophobicContact CD1-CG 3.96Å; Y234-E305 HydrophobicContact CD2-CG 4.08Å; Y234-E305 HydrophobicContact CE1-CG 3.63Å; Y234-E305 HydrophobicContact CE2-CB 4.33Å; Y234-E305 HydrophobicContact CE2-CG 3.74Å; Y234-E305 HydrophobicContact CG-CG 4.18Å
235R86.1Confident78.2Confident110 Ų11045.9 Ų45.942%0.41525%0.247SC..Hα-helixtrans-62.9-46.5178.8-178.2-177.8173-168.70.4112E192 Y231 L233 F237 T239E192-R235 IonicContact OE1-NH1 3.26Å; E192-R235 PolarHBondContact OE1-NH1 2.94Å; Y231-R235 HydrophobicContact CE1-CB 4.26Å; Y231-R235 WeakPolarHBondContact O-CB 3.39Å; Y231-R235 PolarHBondContact O-N 3.45Å; L233-R235 PolarHBondContact O-N 2.94Å; R235-F237 VanDerWaalsContact C-N 3.34Å; R235-T239 WeakPolarHBondContact O-CB 3.35Å; R235-T239 PolarHBondContact O-N 3.08Å; R235-T239 PolarHBondContact O-OG1 3.07Å
236K88Confident80.6Confident44 Ų4443 Ų4319%0.19123%0.226CC..Hα-helixtrans-62.8-43.4178.6-71.7176.9-169.4179.60111.1N232 L233 T239 L240 F262 E265N232-K236 WeakPolarHBondContact O-CB 3.49Å; N232-K236 WeakPolarHBondContact O-CG 3.33Å; N232-K236 PolarHBondContact O-N 3.17Å; L233-K236 PolarHBondContact O-N 3.07Å; K236-T239 PolarHBondContact O-N 3.24Å; K236-L240 PolarHBondContact O-N 3.35Å; K236-F262 HydrophobicContact CB-CB 4.46Å; K236-F262 HydrophobicContact CB-CD1 4.08Å; K236-F262 HydrophobicContact CB-CD2 4.4Å; K236-F262 HydrophobicContact CB-CE1 4.44Å; K236-F262 HydrophobicContact CB-CG 4.07Å; K236-F262 HydrophobicContact CD-CD1 3.87Å; K236-F262 HydrophobicContact CD-CE1 3.99Å; K236-F262 HydrophobicContact CG-CD1 3.71Å; K236-F262 HydrophobicContact CG-CE1 3.68Å; K236-F262 HydrophobicContact CG-CG 4.18Å; K236-F262 HydrophobicContact CG-CZ 4.09Å; K236-E265 WeakPolarHBondContact CD-OE2 3.35Å; K236-E265 WeakPolarHBondContact CE-OE2 3.21Å; K236-E265 IonicContact NZ-OE1 2.84Å; K236-E265 PolarHBondContact NZ-OE1 3.29Å; K236-E265 IonicContact NZ-OE2 2.57Å; K236-E265 PolarHBondContact NZ-OE2 3.08Å
237F89.1Confident82.7Confident9 Ų938 Ų384%0.03919%0.19CC..Hα-helixtrans-59.4-52.8178.1-179.2-90.3000112L233 Y234 R235 T239 L240 T266 F270 M308 F317 I321L233-F237 WeakPolarHBondContact O-CB 3.27Å; L233-F237 PolarHBondContact O-N 3.35Å; Y234-F237 PolarHBondContact O-N 3.16Å; R235-F237 VanDerWaalsContact C-N 3.34Å; F237-T239 VanDerWaalsContact C-N 3.29Å; F237-T239 PolarHBondContact O-N 3.46Å; F237-L240 VanDerWaalsContact O-CB 3.27Å; F237-L240 WeakPolarHBondContact O-CB 3.39Å; F237-L240 PolarHBondContact O-N 3.41Å; F237-L240 VanDerWaalsContact O-N 3.09Å; F237-T266 HydrophobicContact CD2-CG2 3.67Å; F237-T266 HydrophobicContact CE2-CG2 3.96Å; F237-F270 HydrophobicContact CE2-CZ 4.16Å; F237-M308 HydrophobicContact CB-CE 4.01Å; F237-M308 HydrophobicContact CD1-CE 3.63Å; F237-M308 HydrophobicContact CD1-SD 4.31Å; F237-M308 HydrophobicContact CD2-CE 3.88Å; F237-M308 HydrophobicContact CE1-CE 4.04Å; F237-M308 HydrophobicContact CE2-CE 4.25Å; F237-M308 HydrophobicContact CG-CE 3.54Å; F237-M308 HydrophobicContact CZ-CE 4.32Å; F237-F317 HydrophobicContact CE1-CE1 4.16Å; F237-F317 AromaticContact CE1-CZ 3.63Å; F237-F317 HydrophobicContact CE1-CZ 3.63Å; F237-F317 HydrophobicContact CE2-CE1 4.4Å; F237-F317 AromaticContact CZ-CE1 3.6Å; F237-F317 HydrophobicContact CZ-CE1 3.6Å; F237-F317 AromaticContact CZ-CZ 3.45Å; F237-F317 HydrophobicContact CZ-CZ 3.45Å; F237-F317 VanDerWaalsContact CZ-CZ 3.45Å; F237-I321 HydrophobicContact CE1-CD1 4.39Å; F237-I321 HydrophobicContact CE2-CD1 4.4Å; F237-I321 HydrophobicContact CE2-CG1 4.27Å; F237-I321 HydrophobicContact CE2-CG2 4.35Å; F237-I321 HydrophobicContact CZ-CD1 3.65Å; F237-I321 HydrophobicContact CZ-CG1 3.79Å
238W89.9Confident84.4Confident1 Ų138.9 Ų38.90%0.00420%0.197CC..Hα-helixtrans-72.7-23.1-179.2-68113.9000113.5T186 F188 Y234 L240 Q241 F301 T303 F317T186-W238 HydrophobicContact CG2-CE3 3.77Å; T186-W238 HydrophobicContact CG2-CZ3 3.97Å; F188-W238 HydrophobicContact CB-CB 3.95Å; F188-W238 HydrophobicContact CB-CG 4.01Å; F188-W238 HydrophobicContact CD1-CB 3.63Å; F188-W238 HydrophobicContact CD2-CB 3.62Å; F188-W238 HydrophobicContact CD2-CG 4.37Å; F188-W238 HydrophobicContact CE1-CB 3.92Å; F188-W238 HydrophobicContact CE2-CB 3.91Å; F188-W238 HydrophobicContact CG-CB 3.47Å; F188-W238 VanDerWaalsContact CG-CB 3.47Å; F188-W238 HydrophobicContact CG-CG 4.08Å; F188-W238 HydrophobicContact CZ-CB 4.04Å; Y234-W238 AromaticContact CD2-CD1 3.37Å; Y234-W238 AromaticContact CD2-NE1 3.24Å; Y234-W238 AromaticContact CE2-CD1 3.19Å; Y234-W238 HydrophobicContact CE2-CG 4.44Å; Y234-W238 AromaticContact CE2-NE1 3Å; Y234-W238 AromaticContact CG-CD1 3.86Å; Y234-W238 AromaticContact CZ-CD1 3.53Å; Y234-W238 AromaticContact CZ-NE1 3.79Å; Y234-W238 PolarHBondContact O-N 2.88Å; W238-L240 VanDerWaalsContact C-N 3.26Å; W238-L240 PolarHBondContact O-N 3.48Å; W238-Q241 HydrophobicContact CE3-CB 4.43Å; W238-Q241 VanDerWaalsContact O-CB 3.27Å; W238-Q241 WeakPolarHBondContact O-CB 3.1Å; W238-Q241 PolarHBondContact O-N 2.69Å; W238-Q241 VanDerWaalsContact O-N 3.13Å; W238-F301 HydrophobicContact CH2-CB 3.71Å; W238-F301 HydrophobicContact CH2-CG 4.19Å; W238-F301 HydrophobicContact CZ3-CB 3.83Å; W238-F301 HydrophobicContact CZ3-CD2 4.11Å; W238-F301 HydrophobicContact CZ3-CG 4.11Å; W238-T303 HydrophobicContact CD2-CG2 4.04Å; W238-T303 HydrophobicContact CE3-CG2 3.95Å; W238-T303 HydrophobicContact CH2-CG2 4.03Å; W238-T303 HydrophobicContact CZ2-CG2 4.07Å; W238-T303 HydrophobicContact CZ3-CG2 3.95Å; W238-F317 HydrophobicContact CH2-CE2 4.21Å; W238-F317 HydrophobicContact CH2-CZ 4.19Å
239T89.1Confident85.9Confident32 Ų3236.5 Ų36.520%0.19618%0.175CC..Hα-helixtrans-65.7-30.8170.2-55.10000111.6R235 K236 F237 Q241 D242 Y243 F262R235-T239 WeakPolarHBondContact O-CB 3.35Å; R235-T239 PolarHBondContact O-N 3.08Å; R235-T239 PolarHBondContact O-OG1 3.07Å; K236-T239 PolarHBondContact O-N 3.24Å; F237-T239 VanDerWaalsContact C-N 3.29Å; F237-T239 PolarHBondContact O-N 3.46Å; T239-Q241 PolarHBondContact O-N 3.5Å; T239-D242 PolarHBondContact O-N 2.83Å; T239-Y243 HydrophobicContact CG2-CE2 4.24Å; T239-Y243 WeakPolarHBondContact O-CD2 3.45Å; T239-F262 HydrophobicContact CG2-CD2 4.24Å; T239-F262 HydrophobicContact CG2-CE2 3.87Å
240L91.3Very high87.1Confident4 Ų435.8 Ų35.82%0.02117%0.172CC..Hα-helixtrans-60.1-32.1171.9-69.7166.6000112.6K236 F237 W238 D242 Y243 F244 F259 F262 S263 T266 Y325K236-L240 PolarHBondContact O-N 3.35Å; F237-L240 VanDerWaalsContact O-CB 3.27Å; F237-L240 WeakPolarHBondContact O-CB 3.39Å; F237-L240 PolarHBondContact O-N 3.41Å; F237-L240 VanDerWaalsContact O-N 3.09Å; W238-L240 VanDerWaalsContact C-N 3.26Å; W238-L240 PolarHBondContact O-N 3.48Å; L240-D242 PolarHBondContact O-N 3.18Å; L240-Y243 HydrophobicContact CD2-CD2 4.46Å; L240-Y243 WeakPolarHBondContact O-CB 3.47Å; L240-Y243 PolarHBondContact O-N 2.87Å; L240-F244 HydrophobicContact CB-CE2 4.07Å; L240-F244 VanDerWaalsContact O-CD2 3.26Å; L240-F244 WeakPolarHBondContact O-CD2 3.5Å; L240-F244 PolarHBondContact O-N 2.93Å; L240-F259 HydrophobicContact CD2-CD2 3.69Å; L240-F259 HydrophobicContact CD2-CE2 3.94Å; L240-F262 HydrophobicContact CD1-CB 4.2Å; L240-F262 HydrophobicContact CD2-CB 3.7Å; L240-F262 HydrophobicContact CG-CB 3.87Å; L240-S263 WeakPolarHBondContact CD2-OG 3.36Å; L240-T266 HydrophobicContact CD1-CG2 4.37Å; L240-T266 VanDerWaalsContact CD1-OG1 3.29Å; L240-T266 WeakPolarHBondContact CD1-OG1 3.25Å; L240-Y325 WeakPolarHBondContact CD1-OH 3.44Å
241Q91.3Very high87.9Confident18 Ų1833.8 Ų33.88%0.08416%0.158CC..Hα-helixtrans-62.8-31.7179.3-163.461.166.100113T186 W238 T239 Y243 F244 R245T186-Q241 HydrophobicContact CG2-CG 4.12Å; T186-Q241 VanDerWaalsContact OG1-CG 3.3Å; T186-Q241 WeakPolarHBondContact OG1-CG 3.48Å; W238-Q241 HydrophobicContact CE3-CB 4.43Å; W238-Q241 VanDerWaalsContact O-CB 3.27Å; W238-Q241 WeakPolarHBondContact O-CB 3.1Å; W238-Q241 PolarHBondContact O-N 2.69Å; W238-Q241 VanDerWaalsContact O-N 3.13Å; T239-Q241 PolarHBondContact O-N 3.5Å; Q241-Y243 VanDerWaalsContact C-N 3.35Å; Q241-F244 PolarHBondContact O-N 3.03Å; Q241-R245 WeakPolarHBondContact O-CB 3.36Å; Q241-R245 PolarHBondContact O-N 3.13Å
242D89Confident88.5Confident32 Ų3236.9 Ų36.917%0.17118%0.176CC..Hα-helixtrans-67.8-35.3174.4-81.1-32.1000111.5T239 L240 R245 N246T239-D242 PolarHBondContact O-N 2.83Å; L240-D242 PolarHBondContact O-N 3.18Å; D242-R245 PolarHBondContact O-N 2.89Å; D242-R245 IonicContact OD1-NH1 2.74Å; D242-R245 PolarHBondContact OD1-NH1 2.99Å; D242-N246 PolarHBondContact O-N 3.18Å
243Y91.1Very high88.8Confident22 Ų2241.4 Ų41.49%0.08619%0.192CC..Hα-helixtrans-69-39173.2-66.9-67.6000112.4T239 L240 Q241 R245 N246 Q249 F259T239-Y243 HydrophobicContact CG2-CE2 4.24Å; T239-Y243 WeakPolarHBondContact O-CD2 3.45Å; L240-Y243 HydrophobicContact CD2-CD2 4.46Å; L240-Y243 WeakPolarHBondContact O-CB 3.47Å; L240-Y243 PolarHBondContact O-N 2.87Å; Q241-Y243 VanDerWaalsContact C-N 3.35Å; Y243-R245 VanDerWaalsContact C-N 3.29Å; Y243-R245 PolarHBondContact O-N 3.25Å; Y243-N246 CarbonylContact O-C 3.57Å; Y243-N246 PolarHBondContact O-N 3.2Å; Y243-Q249 HydrophobicContact CD1-CB 4.13Å; Y243-Q249 HydrophobicContact CE1-CB 4.29Å; Y243-F259 HydrophobicContact CD2-CB 4.37Å; Y243-F259 HydrophobicContact CD2-CD2 4.04Å; Y243-F259 HydrophobicContact CE2-CB 4.4Å; Y243-F259 HydrophobicContact CG-CB 4.45Å; Y243-F259 AromaticContact CG-CD2 3.96Å; Y243-F259 HydrophobicContact CG-CD2 3.96Å
244F91.8Very high89Confident32 Ų3247.3 Ų47.314%0.1422%0.217CC..Hα-helixtrans-64.3-34.2173-66.3-53000112.5L240 Q241 Q324 Y325 L328L240-F244 HydrophobicContact CB-CE2 4.07Å; L240-F244 VanDerWaalsContact O-CD2 3.26Å; L240-F244 WeakPolarHBondContact O-CD2 3.5Å; L240-F244 PolarHBondContact O-N 2.93Å; Q241-F244 PolarHBondContact O-N 3.03Å; F244-Q324 HydrophobicContact CD1-CB 3.98Å; F244-Q324 HydrophobicContact CD2-CB 4.31Å; F244-Q324 VanDerWaalsContact CD2-OE1 3.24Å; F244-Q324 HydrophobicContact CE1-CB 4.11Å; F244-Q324 HydrophobicContact CE2-CB 4.43Å; F244-Q324 HydrophobicContact CG-CB 4.11Å; F244-Q324 HydrophobicContact CZ-CB 4.34Å; F244-Y325 AromaticContact CE1-CD1 3.93Å; F244-Y325 HydrophobicContact CE1-CD1 3.93Å; F244-Y325 HydrophobicContact CE1-CD2 4.44Å; F244-Y325 HydrophobicContact CE1-CE1 4.16Å; F244-Y325 HydrophobicContact CE1-CG 4.08Å; F244-Y325 HydrophobicContact CE2-CE2 4.43Å; F244-Y325 AromaticContact CZ-CD1 3.83Å; F244-Y325 HydrophobicContact CZ-CD1 3.83Å; F244-Y325 AromaticContact CZ-CD2 3.8Å; F244-Y325 HydrophobicContact CZ-CD2 3.8Å; F244-Y325 AromaticContact CZ-CE1 3.72Å; F244-Y325 HydrophobicContact CZ-CE1 3.72Å; F244-Y325 AromaticContact CZ-CE2 3.69Å; F244-Y325 HydrophobicContact CZ-CE2 3.69Å; F244-Y325 AromaticContact CZ-CG 3.86Å; F244-Y325 HydrophobicContact CZ-CG 3.86Å; F244-Y325 AromaticContact CZ-CZ 3.65Å; F244-L328 HydrophobicContact CD1-CB 4.12Å; F244-L328 HydrophobicContact CD1-CD2 3.72Å; F244-L328 HydrophobicContact CD1-CG 4.48Å; F244-L328 HydrophobicContact CE1-CB 4.26Å; F244-L328 HydrophobicContact CE1-CD2 3.7Å
245R89.5Confident89.3Confident64 Ų6448.2 Ų48.224%0.24222%0.224CC..Hα-helixtrans-71.5-37.9176.2171.1177.2158.4-132.7-6112.5L182 N184 Q241 D242 Y243L182-R245 HydrophobicContact CD2-CG 4.45Å; L182-R245 PolarHBondContact O-NE 2.93Å; L182-R245 PolarHBondContact O-NH2 2.94Å; N184-R245 WeakPolarHBondContact O-CD 3.41Å; Q241-R245 WeakPolarHBondContact O-CB 3.36Å; Q241-R245 PolarHBondContact O-N 3.13Å; D242-R245 PolarHBondContact O-N 2.89Å; D242-R245 IonicContact OD1-NH1 2.74Å; D242-R245 PolarHBondContact OD1-NH1 2.99Å; Y243-R245 VanDerWaalsContact C-N 3.29Å; Y243-R245 PolarHBondContact O-N 3.25Å
246N89.6Confident89.6Confident34 Ų3443.6 Ų43.618%0.18221%0.207CC..  trans-126.183.3179.8-171.62.3000111.8L182 D242 Y243 V248 Q249L182-N246 HydrophobicContact CD2-CB 3.96Å; D242-N246 PolarHBondContact O-N 3.18Å; Y243-N246 CarbonylContact O-C 3.57Å; Y243-N246 PolarHBondContact O-N 3.2Å; N246-V248 PolarHBondContact O-N 3.04Å; N246-V248 VanDerWaalsContact O-N 3.09Å; N246-V248 PolarHBondContact OD1-N 3.25Å; N246-Q249 HydrophobicContact CB-CG 4.23Å; N246-Q249 PolarHBondContact ND2-NE2 3.08Å; N246-Q249 PolarHBondContact O-N 3.22Å
247P89.7Confident89.8Confident6 Ų647.8 Ų47.84%0.03923%0.228CC..G310 helixtrans-68.1-13.5-175.929.7-37.7000113.3F180 Q249 C250 L328 Y331F180-P247 HydrophobicContact CD1-CG 4.04Å; F180-P247 HydrophobicContact CD2-CG 4.24Å; F180-P247 HydrophobicContact CE1-CG 3.47Å; F180-P247 VanDerWaalsContact CE1-CG 3.47Å; F180-P247 HydrophobicContact CE2-CG 3.7Å; F180-P247 HydrophobicContact CG-CG 4.41Å; F180-P247 HydrophobicContact CZ-CG 3.29Å; P247-Q249 PolarHBondContact O-N 3.1Å; P247-C250 WeakPolarHBondContact O-CB 3.26Å; P247-C250 PolarHBondContact O-N 3.35Å; P247-L328 HydrophobicContact CB-CD1 3.45Å; P247-L328 VanDerWaalsContact CB-CD1 3.45Å; P247-Y331 HydrophobicContact CB-CD1 3.64Å; P247-Y331 HydrophobicContact CB-CE1 3.64Å; P247-Y331 HydrophobicContact CG-CD1 3.84Å; P247-Y331 HydrophobicContact CG-CE1 3.59Å
248V87.8Confident89.9Confident65 Ų6548.8 Ų48.839%0.39424%0.235SC..G310 helixtrans-67-26.5177-175.60000111.3F180 N246 C250 Y251F180-V248 HydrophobicContact CD2-CG2 4.28Å; F180-V248 HydrophobicContact CE2-CG2 3.95Å; N246-V248 PolarHBondContact O-N 3.04Å; N246-V248 VanDerWaalsContact O-N 3.09Å; N246-V248 PolarHBondContact OD1-N 3.25Å; V248-C250 PolarHBondContact O-N 3.44Å; V248-Y251 WeakPolarHBondContact O-CD2 3.44Å; V248-Y251 PolarHBondContact O-N 3.21Å
249Q88.7Confident90.1Very high75 Ų7548.7 Ų48.735%0.3524%0.235SC..G310 helixtrans-64.4-25.2176.8-66.11790.600112.6Y243 N246 P247 Y251 D252 S255Y243-Q249 HydrophobicContact CD1-CB 4.13Å; Y243-Q249 HydrophobicContact CE1-CB 4.29Å; N246-Q249 HydrophobicContact CB-CG 4.23Å; N246-Q249 PolarHBondContact ND2-NE2 3.08Å; N246-Q249 PolarHBondContact O-N 3.22Å; P247-Q249 PolarHBondContact O-N 3.1Å; Q249-Y251 PolarHBondContact O-N 2.89Å; Q249-Y251 VanDerWaalsContact O-N 3.16Å; Q249-D252 PolarHBondContact O-N 3.33Å; Q249-D252 VanDerWaalsContact O-N 3.13Å; Q249-S255 WeakPolarHBondContact O-CB 3.49Å
250C89Confident90.3Very high0 Ų049 Ų490%024%0.235CC..G310 helixtrans-67.5-11.7178.8-63.50000113.6P247 V248 W256 L332P247-C250 WeakPolarHBondContact O-CB 3.26Å; P247-C250 PolarHBondContact O-N 3.35Å; V248-C250 PolarHBondContact O-N 3.44Å; C250-W256 HydrophobicContact CB-CE3 3.88Å; C250-W256 HydrophobicContact CB-CZ3 4.06Å; C250-W256 VanDerWaalsContact O-CE3 3.25Å; C250-L332 HydrophobicContact CB-CD1 4.26Å; C250-L332 HydrophobicContact CB-CD2 3.99Å
251Y87Confident90.3Very high41 Ų4154.7 Ų54.716%0.16126%0.26CS..G310 helixtrans-85.6-12.3174.5-64.6-74000113.5V248 Q249 L332 K339 C343 L345V248-Y251 WeakPolarHBondContact O-CD2 3.44Å; V248-Y251 PolarHBondContact O-N 3.21Å; Q249-Y251 PolarHBondContact O-N 2.89Å; Q249-Y251 VanDerWaalsContact O-N 3.16Å; Y251-L332 HydrophobicContact CE1-CD2 4.4Å; Y251-L332 HydrophobicContact CE2-CD2 3.94Å; Y251-L332 PolarHBondContact OH-O 3.29Å; Y251-K339 PolarHBondContact OH-NZ 3.22Å; Y251-C343 HydrophobicContact CD1-CB 4.03Å; Y251-C343 HydrophobicContact CD2-CB 3.9Å; Y251-C343 HydrophobicContact CE1-CB 3.87Å; Y251-C343 WeakPolarHBondContact CE1-O 3.39Å; Y251-C343 HydrophobicContact CE2-CB 3.73Å; Y251-C343 HydrophobicContact CG-CB 4.05Å; Y251-L345 HydrophobicContact CD1-CD2 4.14Å; Y251-L345 HydrophobicContact CE1-CD2 3.85Å; Y251-L345 HydrophobicContact CE1-CG 4.15Å
252D89.5Confident90.4Very high84 Ų8455.5 Ų55.545%0.44926%0.263SS..SBendtrans-83.1139.7172.8170.947.9000111.2Q249 F254 S255 W256Q249-D252 PolarHBondContact O-N 3.33Å; Q249-D252 VanDerWaalsContact O-N 3.13Å; D252-F254 PolarHBondContact O-N 2.96Å; D252-S255 PolarHBondContact O-N 2.97Å; D252-S255 WeakPolarHBondContact OD2-CB 3.35Å; D252-S255 PolarHBondContact OD2-N 3.41Å; D252-S255 PolarHBondContact OD2-OG 2.83Å; D252-W256 WeakPolarHBondContact O-CB 3.33Å; D252-W256 PolarHBondContact O-N 3.49Å
253K87.5Confident90.6Very high165 Ų16554 Ų5472%0.71726%0.255SS*.Hα-helixtrans-63.8-45.4-172.7-69.5-175.4179.2-178.70112.8M257K253-M257 WeakPolarHBondContact O-CG 3.43Å; K253-M257 PolarHBondContact O-N 3.49Å; K253-M257 VanDerWaalsContact O-N 3.1Å
254F89.1Confident90.7Very high153 Ų15356.8 Ų56.867%0.67127%0.271SS*.Hα-helixtrans-70.2-43.5-177.7-179.3-95.8000111.1D252 W256 M257 T258D252-F254 PolarHBondContact O-N 2.96Å; F254-W256 VanDerWaalsContact C-N 3.34Å; F254-W256 PolarHBondContact O-N 3.26Å; F254-M257 PolarHBondContact O-N 3.11Å; F254-T258 PolarHBondContact O-N 3.35Å; F254-T258 VanDerWaalsContact O-N 3.12Å; F254-T258 PolarHBondContact O-OG1 3.34Å
255S90.8Very high90.6Very high22 Ų2258.1 Ų58.115%0.15428%0.278CS..Hα-helixtrans-60.6-42.7175.6-60.90000111.8Q249 D252 T258 F259Q249-S255 WeakPolarHBondContact O-CB 3.49Å; D252-S255 PolarHBondContact O-N 2.97Å; D252-S255 WeakPolarHBondContact OD2-CB 3.35Å; D252-S255 PolarHBondContact OD2-N 3.41Å; D252-S255 PolarHBondContact OD2-OG 2.83Å; S255-T258 PolarHBondContact O-N 3.18Å; S255-F259 WeakPolarHBondContact O-CB 3.43Å; S255-F259 PolarHBondContact O-N 3.03Å
256W92.3Very high90.6Very high13 Ų1355.2 Ų55.25%0.04927%0.268CS..Hα-helixtrans-62.9-46.9175.9-177.9-103.5000112.8C250 D252 F254 T258 F259 L260 L332 Q349 W352 I353C250-W256 HydrophobicContact CB-CE3 3.88Å; C250-W256 HydrophobicContact CB-CZ3 4.06Å; C250-W256 VanDerWaalsContact O-CE3 3.25Å; D252-W256 WeakPolarHBondContact O-CB 3.33Å; D252-W256 PolarHBondContact O-N 3.49Å; F254-W256 VanDerWaalsContact C-N 3.34Å; F254-W256 PolarHBondContact O-N 3.26Å; W256-T258 VanDerWaalsContact C-N 3.25Å; W256-T258 PolarHBondContact O-N 3.06Å; W256-F259 HydrophobicContact CE3-CD1 4.03Å; W256-F259 HydrophobicContact CH2-CD1 4.41Å; W256-F259 HydrophobicContact CH2-CE1 4.39Å; W256-F259 AromaticContact CZ3-CD1 3.85Å; W256-F259 HydrophobicContact CZ3-CD1 3.85Å; W256-F259 HydrophobicContact CZ3-CE1 4.04Å; W256-F259 WeakPolarHBondContact O-CB 3.45Å; W256-F259 PolarHBondContact O-N 2.68Å; W256-L260 HydrophobicContact CD2-CG 4.48Å; W256-L260 HydrophobicContact CZ2-CD2 3.84Å; W256-L260 HydrophobicContact CZ2-CG 4.41Å; W256-L260 WeakPolarHBondContact O-CG 3.44Å; W256-L260 PolarHBondContact O-N 3.01Å; W256-L332 HydrophobicContact CZ3-CD1 4.05Å; W256-Q349 VanDerWaalsContact CG-NE2 3.34Å; W256-Q349 HydrophobicContact CZ2-CB 3.88Å; W256-Q349 HydrophobicContact CZ2-CG 4.09Å; W256-W352 AromaticContact CH2-CE3 3.98Å; W256-W352 HydrophobicContact CH2-CE3 3.98Å; W256-W352 AromaticContact CH2-CZ3 3.94Å; W256-W352 HydrophobicContact CH2-CZ3 3.94Å; W256-W352 AromaticContact CZ2-CE3 3.84Å; W256-W352 HydrophobicContact CZ2-CE3 3.84Å; W256-W352 HydrophobicContact CZ2-CZ3 4.18Å; W256-I353 HydrophobicContact CH2-CD1 4Å; W256-I353 HydrophobicContact CH2-CG1 4.02Å
257M91.9Very high90.7Very high131 Ų13153.8 Ų53.865%0.64526%0.26SS*.Hα-helixtrans-59.8-38.2177.4-72.6-178.6-177.800112.3K253 F254 K261K253-M257 WeakPolarHBondContact O-CG 3.43Å; K253-M257 PolarHBondContact O-N 3.49Å; K253-M257 VanDerWaalsContact O-N 3.1Å; F254-M257 PolarHBondContact O-N 3.11Å; M257-K261 PolarHBondContact O-N 3.17Å
258T92.1Very high90.7Very high30 Ų3056 Ų5618%0.18428%0.279CS..Hα-helixtrans-67.3-45176.4-55.90000111F254 S255 W256 L260 K261 F262F254-T258 PolarHBondContact O-N 3.35Å; F254-T258 VanDerWaalsContact O-N 3.12Å; F254-T258 PolarHBondContact O-OG1 3.34Å; S255-T258 PolarHBondContact O-N 3.18Å; W256-T258 VanDerWaalsContact C-N 3.25Å; W256-T258 PolarHBondContact O-N 3.06Å; T258-L260 PolarHBondContact O-N 3.39Å; T258-K261 PolarHBondContact O-N 2.8Å; T258-F262 HydrophobicContact CG2-CD2 3.84Å; T258-F262 HydrophobicContact CG2-CE1 4.16Å; T258-F262 HydrophobicContact CG2-CE2 3.34Å; T258-F262 HydrophobicContact CG2-CG 4.44Å; T258-F262 HydrophobicContact CG2-CZ 3.52Å; T258-F262 WeakPolarHBondContact O-CG 3.45Å; T258-F262 PolarHBondContact O-N 3.16Å
259F93.9Very high90.7Very high0 Ų054.5 Ų54.50%027%0.27CS..Hα-helixtrans-59.7-44.3176.1173.8-101.1000112.5L240 Y243 S255 W256 F262 S263 Y325 L328 F329 W352L240-F259 HydrophobicContact CD2-CD2 3.69Å; L240-F259 HydrophobicContact CD2-CE2 3.94Å; Y243-F259 HydrophobicContact CD2-CB 4.37Å; Y243-F259 HydrophobicContact CD2-CD2 4.04Å; Y243-F259 HydrophobicContact CE2-CB 4.4Å; Y243-F259 HydrophobicContact CG-CB 4.45Å; Y243-F259 AromaticContact CG-CD2 3.96Å; Y243-F259 HydrophobicContact CG-CD2 3.96Å; S255-F259 WeakPolarHBondContact O-CB 3.43Å; S255-F259 PolarHBondContact O-N 3.03Å; W256-F259 HydrophobicContact CE3-CD1 4.03Å; W256-F259 HydrophobicContact CH2-CD1 4.41Å; W256-F259 HydrophobicContact CH2-CE1 4.39Å; W256-F259 AromaticContact CZ3-CD1 3.85Å; W256-F259 HydrophobicContact CZ3-CD1 3.85Å; W256-F259 HydrophobicContact CZ3-CE1 4.04Å; W256-F259 WeakPolarHBondContact O-CB 3.45Å; W256-F259 PolarHBondContact O-N 2.68Å; F259-F262 PolarHBondContact O-N 3.2Å; F259-S263 WeakPolarHBondContact CE2-OG 3.17Å; F259-S263 WeakPolarHBondContact CZ-OG 3.45Å; F259-S263 WeakPolarHBondContact O-CB 2.95Å; F259-S263 PolarHBondContact O-N 2.54Å; F259-S263 PolarHBondContact O-OG 2.89Å; F259-Y325 HydrophobicContact CE2-CE1 4.26Å; F259-Y325 HydrophobicContact CZ-CD1 4.39Å; F259-Y325 AromaticContact CZ-CE1 3.93Å; F259-Y325 HydrophobicContact CZ-CE1 3.93Å; F259-L328 HydrophobicContact CE1-CD2 4.46Å; F259-L328 HydrophobicContact CE2-CD2 3.83Å; F259-L328 HydrophobicContact CZ-CD2 3.57Å; F259-F329 HydrophobicContact CE1-CE1 4.44Å; F259-F329 HydrophobicContact CZ-CE1 4.38Å; F259-W352 HydrophobicContact CD1-CH2 4.46Å; F259-W352 AromaticContact CE1-CH2 3.87Å; F259-W352 HydrophobicContact CE1-CH2 3.87Å; F259-W352 AromaticContact CE1-CZ3 3.92Å; F259-W352 HydrophobicContact CE1-CZ3 3.92Å
260L93.2Very high90.7Very high39 Ų3951.2 Ų51.220%0.20425%0.254CS..Hα-helixtrans-56.2-55.3175.3-73178.4000110.8W256 T258 F262 S263 D264 W352W256-L260 HydrophobicContact CD2-CG 4.48Å; W256-L260 HydrophobicContact CZ2-CD2 3.84Å; W256-L260 HydrophobicContact CZ2-CG 4.41Å; W256-L260 WeakPolarHBondContact O-CG 3.44Å; W256-L260 PolarHBondContact O-N 3.01Å; T258-L260 PolarHBondContact O-N 3.39Å; L260-F262 PolarHBondContact O-N 2.86Å; L260-S263 PolarHBondContact O-N 3.22Å; L260-D264 PolarHBondContact O-N 3.17Å; L260-W352 HydrophobicContact CD2-CD2 3.24Å; L260-W352 HydrophobicContact CD2-CE3 3.5Å; L260-W352 HydrophobicContact CD2-CG 3.84Å; L260-W352 HydrophobicContact CD2-CH2 3.71Å; L260-W352 HydrophobicContact CD2-CZ2 3.45Å; L260-W352 VanDerWaalsContact CD2-CZ2 3.45Å; L260-W352 HydrophobicContact CD2-CZ3 3.73Å
261K92.4Very high90.6Very high123 Ų12356.9 Ų56.954%0.53528%0.279SS..Hα-helixtrans-58-46.7-177.8-175.7179.2179.9-1800112M257 T258 E265M257-K261 PolarHBondContact O-N 3.17Å; T258-K261 PolarHBondContact O-N 2.8Å; K261-E265 WeakPolarHBondContact CE-OE1 3.29Å; K261-E265 WeakPolarHBondContact O-CG 3.32Å; K261-E265 PolarHBondContact O-N 3.46Å
262F92.9Very high90.6Very high34 Ų3459.5 Ų59.515%0.14930%0.303CS..Hα-helixtrans-70.9-33.7-178.2-65-6.6000112K236 T239 L240 T258 F259 L260 T266K236-F262 HydrophobicContact CB-CB 4.46Å; K236-F262 HydrophobicContact CB-CD1 4.08Å; K236-F262 HydrophobicContact CB-CD2 4.4Å; K236-F262 HydrophobicContact CB-CE1 4.44Å; K236-F262 HydrophobicContact CB-CG 4.07Å; K236-F262 HydrophobicContact CD-CD1 3.87Å; K236-F262 HydrophobicContact CD-CE1 3.99Å; K236-F262 HydrophobicContact CG-CD1 3.71Å; K236-F262 HydrophobicContact CG-CE1 3.68Å; K236-F262 HydrophobicContact CG-CG 4.18Å; K236-F262 HydrophobicContact CG-CZ 4.09Å; T239-F262 HydrophobicContact CG2-CD2 4.24Å; T239-F262 HydrophobicContact CG2-CE2 3.87Å; L240-F262 HydrophobicContact CD1-CB 4.2Å; L240-F262 HydrophobicContact CD2-CB 3.7Å; L240-F262 HydrophobicContact CG-CB 3.87Å; T258-F262 HydrophobicContact CG2-CD2 3.84Å; T258-F262 HydrophobicContact CG2-CE1 4.16Å; T258-F262 HydrophobicContact CG2-CE2 3.34Å; T258-F262 HydrophobicContact CG2-CG 4.44Å; T258-F262 HydrophobicContact CG2-CZ 3.52Å; T258-F262 WeakPolarHBondContact O-CG 3.45Å; T258-F262 PolarHBondContact O-N 3.16Å; F259-F262 PolarHBondContact O-N 3.2Å; L260-F262 PolarHBondContact O-N 2.86Å; F262-T266 WeakPolarHBondContact O-CB 3.5Å; F262-T266 PolarHBondContact O-N 3.22Å; F262-T266 PolarHBondContact O-OG1 3.49Å
263S93.3Very high90.2Very high0 Ų057.9 Ų57.90%029%0.292CS..Hα-helixtrans-69.3-45.9176.8-61.90000112L240 F259 L260 E265 T266 L267 Y325L240-S263 WeakPolarHBondContact CD2-OG 3.36Å; F259-S263 WeakPolarHBondContact CE2-OG 3.17Å; F259-S263 WeakPolarHBondContact CZ-OG 3.45Å; F259-S263 WeakPolarHBondContact O-CB 2.95Å; F259-S263 PolarHBondContact O-N 2.54Å; F259-S263 PolarHBondContact O-OG 2.89Å; L260-S263 PolarHBondContact O-N 3.22Å; S263-E265 VanDerWaalsContact C-N 3.32Å; S263-E265 PolarHBondContact O-N 3.33Å; S263-T266 PolarHBondContact O-N 2.9Å; S263-L267 WeakPolarHBondContact O-CB 3.4Å; S263-L267 VanDerWaalsContact O-CG 3.31Å; S263-L267 WeakPolarHBondContact O-CG 3.46Å; S263-L267 PolarHBondContact O-N 3.38Å; S263-Y325 WeakPolarHBondContact CA-OH 3.3Å; S263-Y325 WeakPolarHBondContact CB-OH 3.38Å; S263-Y325 WeakPolarHBondContact OG-CE1 3.46Å; S263-Y325 PolarHBondContact OG-OH 3.22Å; S263-Y325 VanDerWaalsContact OG-OH 3.06Å
264D92.2Very high89.8Confident81 Ų8156.7 Ų56.743%0.43329%0.287SS..Hα-helixtrans-60.6-42.7178.1-70.9-21.2000111.3L260 A268L260-D264 PolarHBondContact O-N 3.17Å; D264-A268 WeakPolarHBondContact O-CB 3.42Å; D264-A268 PolarHBondContact O-N 2.9Å
265E89.9Confident89.2Confident61 Ų6151 Ų5129%0.28526%0.264SS..Hα-helixtrans-63.7-44.6175.3-71.5-177.2-151.800112K236 K261 S263 A268 V269K236-E265 WeakPolarHBondContact CD-OE2 3.35Å; K236-E265 WeakPolarHBondContact CE-OE2 3.21Å; K236-E265 IonicContact NZ-OE1 2.84Å; K236-E265 PolarHBondContact NZ-OE1 3.29Å; K236-E265 IonicContact NZ-OE2 2.57Å; K236-E265 PolarHBondContact NZ-OE2 3.08Å; K261-E265 WeakPolarHBondContact CE-OE1 3.29Å; K261-E265 WeakPolarHBondContact O-CG 3.32Å; K261-E265 PolarHBondContact O-N 3.46Å; S263-E265 VanDerWaalsContact C-N 3.32Å; S263-E265 PolarHBondContact O-N 3.33Å; E265-A268 PolarHBondContact O-N 3.23Å; E265-V269 WeakPolarHBondContact O-CG2 3.43Å; E265-V269 PolarHBondContact O-N 3.49Å; E265-V269 VanDerWaalsContact O-N 3.08Å
266T89.8Confident87.9Confident3 Ų357.3 Ų57.32%0.01830%0.295CS..Hα-helixtrans-66.3-44.8-180-59.80000112F237 L240 F262 S263 A268 V269 F270F237-T266 HydrophobicContact CD2-CG2 3.67Å; F237-T266 HydrophobicContact CE2-CG2 3.96Å; L240-T266 HydrophobicContact CD1-CG2 4.37Å; L240-T266 VanDerWaalsContact CD1-OG1 3.29Å; L240-T266 WeakPolarHBondContact CD1-OG1 3.25Å; F262-T266 WeakPolarHBondContact O-CB 3.5Å; F262-T266 PolarHBondContact O-N 3.22Å; F262-T266 PolarHBondContact O-OG1 3.49Å; S263-T266 PolarHBondContact O-N 2.9Å; T266-A268 VanDerWaalsContact C-N 3.32Å; T266-A268 PolarHBondContact O-N 2.9Å; T266-V269 WeakPolarHBondContact O-CB 3.4Å; T266-V269 PolarHBondContact O-N 2.79Å; T266-F270 HydrophobicContact CG2-CE2 4.12Å; T266-F270 HydrophobicContact CG2-CZ 4.27Å; T266-F270 PolarHBondContact O-N 3.31Å
267L90.8Very high86.2Confident3 Ų360.7 Ų60.72%0.01632%0.315CS..Hα-helixtrans-68.7-32.2177.8-67.1174.2000111.8S263 V269 F270 K271 L322 Y325 T356 L359 V360 L363S263-L267 WeakPolarHBondContact O-CB 3.4Å; S263-L267 VanDerWaalsContact O-CG 3.31Å; S263-L267 WeakPolarHBondContact O-CG 3.46Å; S263-L267 PolarHBondContact O-N 3.38Å; L267-V269 VanDerWaalsContact C-N 3.34Å; L267-F270 HydrophobicContact CD2-CD2 4.32Å; L267-F270 PolarHBondContact O-N 3.47Å; L267-K271 WeakPolarHBondContact O-CB 3.48Å; L267-K271 PolarHBondContact O-N 2.97Å; L267-L322 HydrophobicContact CD2-CD2 3.93Å; L267-Y325 HydrophobicContact CD2-CD2 4.48Å; L267-Y325 HydrophobicContact CD2-CE2 4.25Å; L267-T356 HydrophobicContact CD1-CG2 3.45Å; L267-T356 VanDerWaalsContact CD1-CG2 3.45Å; L267-L359 HydrophobicContact CB-CD2 4.33Å; L267-L359 HydrophobicContact CD1-CD2 4.36Å; L267-V360 HydrophobicContact CD1-CG2 4.46Å; L267-V360 HydrophobicContact CD2-CG2 4.17Å; L267-L363 HydrophobicContact CD2-CD1 4.04Å
268A90.2Very high84.7Confident54 Ų5459.9 Ų59.945%0.44631%0.311SS..Hα-helixtrans-64.1-38.1171.200000112D264 E265 T266 K271 S272D264-A268 WeakPolarHBondContact O-CB 3.42Å; D264-A268 PolarHBondContact O-N 2.9Å; E265-A268 PolarHBondContact O-N 3.23Å; T266-A268 VanDerWaalsContact C-N 3.32Å; T266-A268 PolarHBondContact O-N 2.9Å; A268-K271 PolarHBondContact O-N 3.45Å; A268-S272 WeakPolarHBondContact O-CB 3.37Å; A268-S272 PolarHBondContact O-N 2.97Å; A268-S272 PolarHBondContact O-OG 2.92Å
269V88.4Confident82.8Confident33 Ų3364.6 Ų64.620%0.233%0.331CS..Hα-helixtrans-63.1-46.1172.3172.70000110.9L233 E265 T266 L267 K271 S272 F273L233-V269 HydrophobicContact CD1-CG2 3.94Å; L233-V269 HydrophobicContact CD2-CG1 4.45Å; L233-V269 HydrophobicContact CD2-CG2 4.14Å; E265-V269 WeakPolarHBondContact O-CG2 3.43Å; E265-V269 PolarHBondContact O-N 3.49Å; E265-V269 VanDerWaalsContact O-N 3.08Å; T266-V269 WeakPolarHBondContact O-CB 3.4Å; T266-V269 PolarHBondContact O-N 2.79Å; L267-V269 VanDerWaalsContact C-N 3.34Å; V269-K271 VanDerWaalsContact C-N 3.31Å; V269-K271 PolarHBondContact O-N 3.34Å; V269-S272 WeakPolarHBondContact CA-OG 3.47Å; V269-S272 PolarHBondContact O-N 2.97Å; V269-S272 PolarHBondContact O-OG 2.91Å; V269-F273 WeakPolarHBondContact O-CB 3.49Å; V269-F273 PolarHBondContact O-N 3.42Å
270F87.9Confident80.7Confident6 Ų668.7 Ų68.73%0.02636%0.364CS..Hα-helixtrans-64.3-33.9176.6-69.5-19.6000113.8F237 T266 L267 F273 L312 R318 I321 L322 L363F237-F270 HydrophobicContact CE2-CZ 4.16Å; T266-F270 HydrophobicContact CG2-CE2 4.12Å; T266-F270 HydrophobicContact CG2-CZ 4.27Å; T266-F270 PolarHBondContact O-N 3.31Å; L267-F270 HydrophobicContact CD2-CD2 4.32Å; L267-F270 PolarHBondContact O-N 3.47Å; F270-F273 VanDerWaalsContact O-O 3.06Å; F270-L312 HydrophobicContact CD1-CD2 4.33Å; F270-L312 HydrophobicContact CE1-CD2 3.57Å; F270-L312 HydrophobicContact CZ-CD2 4.49Å; F270-R318 HydrophobicContact CD1-CG 4.44Å; F270-R318 HydrophobicContact CE1-CG 4.15Å; F270-R318 HydrophobicContact CZ-CG 4.46Å; F270-R318 PolarHBondContact O-NH1 2.96Å; F270-I321 HydrophobicContact CE2-CB 4.25Å; F270-I321 HydrophobicContact CE2-CG2 3.91Å; F270-I321 HydrophobicContact CZ-CB 4.37Å; F270-I321 HydrophobicContact CZ-CG2 4.24Å; F270-L322 HydrophobicContact CD2-CD2 4.1Å; F270-L322 HydrophobicContact CE2-CD2 4.44Å; F270-L363 HydrophobicContact CB-CD1 4.15Å
271K88.1Confident78.8Confident118 Ų11869 Ų6951%0.51337%0.37SS..Hα-helixtrans-72.8-37.7176.9-173177.2-177.2175.40112.7L267 A268 V269 L359 L363L267-K271 WeakPolarHBondContact O-CB 3.48Å; L267-K271 PolarHBondContact O-N 2.97Å; A268-K271 PolarHBondContact O-N 3.45Å; V269-K271 VanDerWaalsContact C-N 3.31Å; V269-K271 PolarHBondContact O-N 3.34Å; K271-L359 HydrophobicContact CD-CD1 4.41Å; K271-L363 HydrophobicContact CB-CD2 4.17Å
272S86.4Confident76.9Confident96 Ų9668.9 Ų68.967%0.67137%0.369SS*.Hα-helixtrans-76.8-36.9-179.654.70000112.3A268 V269 K274A268-S272 WeakPolarHBondContact O-CB 3.37Å; A268-S272 PolarHBondContact O-N 2.97Å; A268-S272 PolarHBondContact O-OG 2.92Å; V269-S272 WeakPolarHBondContact CA-OG 3.47Å; V269-S272 PolarHBondContact O-N 2.97Å; V269-S272 PolarHBondContact O-OG 2.91Å; S272-K274 PolarHBondContact O-N 3.35Å
273F80.9Confident75Confident50 Ų5076.7 Ų76.722%0.21940%0.398CS..SBendtrans-91.998.3175.6-167.1-87.2000110.6I227 V269 F270 L275 R318I227-F273 HydrophobicContact CD1-CD2 3.48Å; I227-F273 VanDerWaalsContact CD1-CD2 3.48Å; I227-F273 HydrophobicContact CD1-CE2 3.58Å; I227-F273 HydrophobicContact CD1-CG 4.35Å; I227-F273 HydrophobicContact CD1-CZ 4.49Å; I227-F273 HydrophobicContact CG1-CD2 4.31Å; I227-F273 HydrophobicContact CG1-CE2 4.3Å; V269-F273 WeakPolarHBondContact O-CB 3.49Å; V269-F273 PolarHBondContact O-N 3.42Å; F270-F273 VanDerWaalsContact O-O 3.06Å; F273-L275 HydrophobicContact CD1-CD2 3.95Å; F273-L275 HydrophobicContact CE1-CD2 3.62Å; F273-R318 PolarHBondContact O-NH1 3.39Å; F273-R318 PolarHBondContact O-NH2 3.43Å
274K78.3Confident72.9Confident141 Ų14184.1 Ų84.161%0.61343%0.43SS*.PPolyproline II helixtrans-84.8130.4173.2-63-164.4178.2-129.90110.1S272 E366S272-K274 PolarHBondContact O-N 3.35Å; K274-E366 IonicContact NZ-OE1 3.52Å; K274-E366 IonicContact NZ-OE2 3.91Å; K274-E366 PolarHBondContact NZ-OE2 3.05Å
275L77.3Confident70.8Confident33 Ų3385.1 Ų85.117%0.17343%0.434CS..PPolyproline II helixtrans-73.6132.7173-64.2-177.3000109.2F273 S313 T367F273-L275 HydrophobicContact CD1-CD2 3.95Å; F273-L275 HydrophobicContact CE1-CD2 3.62Å; L275-S313 VanDerWaalsContact CD2-O 3.27Å; L275-S313 WeakPolarHBondContact CD2-O 3.49Å; L275-T367 HydrophobicContact CD1-CG2 4.34Å
276D64.1Low69Low154 Ų15488.3 Ų88.382%0.82445%0.448SS*.PPolyproline II helixtrans-77.9147.3172.4-143.9-1.7000109.8M278D276-M278 PolarHBondContact O-N 3.01Å
277D56.8Low67.1Low84 Ų8494.2 Ų94.245%0.44948%0.48SS..  trans-68.3100.2-174-163.29.6000109.7Q279 P368D277-Q279 PolarHBondContact O-N 3.22Å; D277-Q279 PolarHBondContact OD2-NE2 3.37Å; D277-P368 WeakPolarHBondContact OD1-CB 3.45Å
278M59.8Low65.1Low114 Ų114100.1 Ų100.156%0.56251%0.511SS*.THydrogen-bonded Turntrans-75.737.1-169.4-130.3167.260.800113D276 A280 S281 K282D276-M278 PolarHBondContact O-N 3.01Å; M278-A280 PolarHBondContact O-N 3.05Å; M278-A280 VanDerWaalsContact O-N 3.13Å; M278-S281 PolarHBondContact O-N 3.47Å; M278-K282 PolarHBondContact O-N 3.46Å
279Q52.9Low63.3Low130 Ų130105.2 Ų105.261%0.60752%0.518SS*.Hα-helixtrans-56.4-27175.6-62.7-169.45.400112.2D277D277-Q279 PolarHBondContact O-N 3.22Å; D277-Q279 PolarHBondContact OD2-NE2 3.37Å
280A48.9Very low61.4Low85 Ų85108 Ų10870%0.70255%0.545SS*.Hα-helixtrans-68.4-30.7173.100000113.5M278M278-A280 PolarHBondContact O-N 3.05Å; M278-A280 VanDerWaalsContact O-N 3.13Å
281S52.6Low59.4Low47 Ų47111.7 Ų111.733%0.32957%0.571SS.*Hα-helixtrans-82.2-27.8-179.6-169.80000112.5M278 R283 K284 M285M278-S281 PolarHBondContact O-N 3.47Å; S281-R283 VanDerWaalsContact C-N 3.28Å; S281-R283 PolarHBondContact O-N 3.24Å; S281-K284 PolarHBondContact O-N 2.98Å; S281-M285 WeakPolarHBondContact O-CB 3.33Å; S281-M285 PolarHBondContact O-N 3.31Å
282K53.7Low57.3Low120 Ų120114.3 Ų114.352%0.52259%0.591SS.*Hα-helixtrans-56.5-40.6173.2-118-177.1-179.3-178.10112.4M278 M285 E286M278-K282 PolarHBondContact O-N 3.46Å; K282-M285 PolarHBondContact O-N 3.11Å; K282-E286 PolarHBondContact O-N 3.01Å
283R52.2Low55.3Low197 Ų197112.4 Ų112.474%0.74359%0.587SS**Hα-helixtrans-67.5-42.2176.3-71.8-178.8179173.90.7112.6S281 D287S281-R283 VanDerWaalsContact C-N 3.28Å; S281-R283 PolarHBondContact O-N 3.24Å; R283-D287 PolarHBondContact O-N 3.26Å
284K49.8Very low53.6Low157 Ų157113.3 Ų113.368%0.68361%0.61SS**Hα-helixtrans-68.4-34.3175.3-100.3-174.9173.3-174.10113S281 L288S281-K284 PolarHBondContact O-N 2.98Å; K284-L288 WeakPolarHBondContact O-CG 3.37Å; K284-L288 PolarHBondContact O-N 2.98Å; K284-L288 VanDerWaalsContact O-N 3.15Å
285M47.9Very low52.4Low102 Ų102113.5 Ų113.550%0.50261%0.613SS.*Hα-helixtrans-77.9-31.8-178.9-159-169.9-170.800112.4S281 K282 L288 R289S281-M285 WeakPolarHBondContact O-CB 3.33Å; S281-M285 PolarHBondContact O-N 3.31Å; K282-M285 PolarHBondContact O-N 3.11Å; M285-L288 PolarHBondContact O-N 3.15Å; M285-R289 WeakPolarHBondContact O-CG 3.33Å; M285-R289 PolarHBondContact O-N 2.87Å
286E51.3Low51.8Low127 Ų127117.2 Ų117.259%0.59364%0.637SS**Hα-helixtrans-66.5-38169.1-82-179.2157.500112K282 R289K282-E286 PolarHBondContact O-N 3.01Å; E286-R289 PolarHBondContact O-N 3.34Å
287D50.3Low52.2Low128 Ų128119.3 Ų119.368%0.68464%0.635SS**Hα-helixtrans-67.1-33.6174.7-77.4-20.6000112.6R283 A290R283-D287 PolarHBondContact O-N 3.26Å; D287-A290 PolarHBondContact O-N 3.41Å
288L49.9Very low53.1Low127 Ų127121.8 Ų121.867%0.66564%0.642SS**Hα-helixtrans-74.2-24.6175.7-76.5162.5000113.6K284 M285 A290 S291K284-L288 WeakPolarHBondContact O-CG 3.37Å; K284-L288 PolarHBondContact O-N 2.98Å; K284-L288 VanDerWaalsContact O-N 3.15Å; M285-L288 PolarHBondContact O-N 3.15Å; L288-A290 PolarHBondContact O-N 3.31Å; L288-S291 PolarHBondContact O-N 3.48Å
289R50.8Low53.9Low160 Ų160119.6 Ų119.660%0.60464%0.641SS**THydrogen-bonded Turntrans-69.1-15.3173.3-77.7177.7177.2179.41.7113.3M285 E286M285-R289 WeakPolarHBondContact O-CG 3.33Å; M285-R289 PolarHBondContact O-N 2.87Å; E286-R289 PolarHBondContact O-N 3.34Å
290A50.4Low55.2Low93 Ų93119.5 Ų119.577%0.76964%0.639SS**THydrogen-bonded Turntrans-83.8-10.2174.500000113.3D287 L288D287-A290 PolarHBondContact O-N 3.41Å; L288-A290 PolarHBondContact O-N 3.31Å
291S45.9Very low56.9Low82 Ų82118.3 Ų118.357%0.57362%0.618SS**SBendtrans-88.7131.1172-174.60000109.5L288 G293L288-S291 PolarHBondContact O-N 3.48Å; S291-G293 PolarHBondContact O-N 2.91Å
292D43.9Very low58.4Low173 Ų173119.6 Ų119.693%0.92562%0.621SS**  trans-64.223.3-177.4-160.127.9000114.6G294D292-G294 PolarHBondContact O-N 3.46Å
293G44.3Very low59.9Low57 Ų57115.6 Ų115.659%0.58861%0.607SS**  trans-76.3111.3173.100000109.5S291 H295S291-G293 PolarHBondContact O-N 2.91Å; G293-H295 PolarHBondContact O-N 3.29Å; G293-H295 VanDerWaalsContact O-N 3.17Å
294G45.1Very low61.4Low68 Ų68108.6 Ų108.670%0.70159%0.588SS**  trans-48123.8176.300000111.2D292 V296D292-G294 PolarHBondContact O-N 3.46Å; G294-V296 PolarHBondContact O-N 3.15Å
295H51.7Low62.8Low146 Ų146101.5 Ų101.568%0.67656%0.557SS**  trans-55.6104.7176-107.3-72.2000109.6G293 Y297G293-H295 PolarHBondContact O-N 3.29Å; G293-H295 VanDerWaalsContact O-N 3.17Å; H295-Y297 PolarHBondContact O-N 2.83Å
296V64.8Low64.4Low111 Ų111103.3 Ų103.367%0.67356%0.562SS**  trans-75.2109.3173.6-177.50000107.8G294 F298G294-V296 PolarHBondContact O-N 3.15Å; V296-F298 HydrophobicContact CG1-CE1 4.23Å; V296-F298 HydrophobicContact CG1-CE2 4.45Å; V296-F298 HydrophobicContact CG1-CZ 4.04Å
297Y73.4Confident65.9Low198 Ų198100.3 Ų100.378%0.77655%0.55SS*.  trans-91.8121.3178.5177.3-100.2000110.7H295 A299H295-Y297 PolarHBondContact O-N 2.83Å; Y297-A299 HydrophobicContact CD1-CB 4.29Å; Y297-A299 HydrophobicContact CE1-CB 3.95Å; Y297-A299 PolarHBondContact O-N 3.48Å
298F76.3Confident67.4Low136 Ų13694.3 Ų94.360%0.59652%0.518SS*.  trans-88.7106.9175.6-60.6-78000110.3V296 L302V296-F298 HydrophobicContact CG1-CE1 4.23Å; V296-F298 HydrophobicContact CG1-CE2 4.45Å; V296-F298 HydrophobicContact CG1-CZ 4.04Å; F298-L302 HydrophobicContact CD1-CD1 4.37Å; F298-L302 HydrophobicContact CD1-CD2 4.28Å
299A75Confident68.9Low67 Ų6790.4 Ų90.455%0.55450%0.497SS*.  trans-78.2-18-177.300000114.4Y297Y297-A299 HydrophobicContact CD1-CB 4.29Å; Y297-A299 HydrophobicContact CE1-CB 3.95Å; Y297-A299 PolarHBondContact O-N 3.48Å
300K81.5Confident70.4Confident129 Ų12988.2 Ų88.256%0.56150%0.497SS*.SBendtrans-128.6158.3-179.4-70.1-164.9176.7-160.60110.9N184N184-K300 PolarHBondContact OD1-NZ 2.88Å
301F84.4Confident72.1Confident60 Ų6084.8 Ų84.826%0.26347%0.465SS..  trans-61.6137.8171.2-63.9-50.4000111.3W238 F317 H320 I321W238-F301 HydrophobicContact CH2-CB 3.71Å; W238-F301 HydrophobicContact CH2-CG 4.19Å; W238-F301 HydrophobicContact CZ3-CB 3.83Å; W238-F301 HydrophobicContact CZ3-CD2 4.11Å; W238-F301 HydrophobicContact CZ3-CG 4.11Å; F301-F317 HydrophobicContact CD1-CD2 4.29Å; F301-F317 AromaticContact CD1-CE2 3.97Å; F301-F317 HydrophobicContact CD1-CE2 3.97Å; F301-F317 HydrophobicContact CE1-CD2 4.34Å; F301-F317 HydrophobicContact CE1-CE2 4.23Å; F301-H320 HydrophobicContact CE1-CB 4.25Å; F301-H320 HydrophobicContact CZ-CB 4.31Å; F301-I321 HydrophobicContact CZ-CD1 4.43Å
302L84.1Confident73.8Confident74 Ų7481 Ų8139%0.38744%0.439SS..  trans-87.7108.1173.2-58168.5000107.5F298 S304 L307 Q311F298-L302 HydrophobicContact CD1-CD1 4.37Å; F298-L302 HydrophobicContact CD1-CD2 4.28Å; L302-S304 PolarHBondContact O-N 3.4Å; L302-L307 HydrophobicContact CD1-CD2 4.07Å; L302-Q311 PolarHBondContact O-NE2 2.95Å; L302-Q311 PolarHBondContact O-OE1 2.9Å
303T84.8Confident75.7Confident36 Ų3675.1 Ų75.122%0.22141%0.411CS..  trans-89.727.3-174.850.20000112.4T186 V187 F188 Y234 W238T186-T303 HydrophobicContact CG2-CG2 3.42Å; T186-T303 VanDerWaalsContact CG2-CG2 3.42Å; V187-T303 VanDerWaalsContact O-CB 3.23Å; V187-T303 WeakPolarHBondContact O-CB 3.4Å; V187-T303 WeakPolarHBondContact O-CG2 3.48Å; V187-T303 PolarHBondContact O-OG1 3.22Å; F188-T303 HydrophobicContact CB-CG2 4.21Å; Y234-T303 WeakPolarHBondContact CE2-O 3.48Å; Y234-T303 PolarHBondContact OH-O 3.06Å; W238-T303 HydrophobicContact CD2-CG2 4.04Å; W238-T303 HydrophobicContact CE3-CG2 3.95Å; W238-T303 HydrophobicContact CH2-CG2 4.03Å; W238-T303 HydrophobicContact CZ2-CG2 4.07Å; W238-T303 HydrophobicContact CZ3-CG2 3.95Å
304S83Confident77.7Confident50 Ų5075.2 Ų75.235%0.3540%0.398SS..  trans-77.7131.7178.7177.90000110.6L302 K306 L307L302-S304 PolarHBondContact O-N 3.4Å; S304-K306 VanDerWaalsContact C-N 3.28Å; S304-K306 PolarHBondContact O-N 2.83Å; S304-L307 PolarHBondContact O-N 3.41Å; S304-L307 VanDerWaalsContact O-N 3.16Å; S304-L307 WeakPolarHBondContact OG-CD1 3.43Å
305E81.1Confident79.7Confident8 Ų872.9 Ų72.94%0.03737%0.371CS..G310 helixtrans-57.3-40.7178.2-70.2174.6-162.200112.4N189 S195 T196 L197 Y234 L307 M308N189-E305 VanDerWaalsContact CB-OE1 3.24Å; N189-E305 WeakPolarHBondContact CB-OE1 3.42Å; N189-E305 PolarHBondContact ND2-OE1 3.43Å; S195-E305 WeakPolarHBondContact CA-OE2 3.41Å; S195-E305 PolarHBondContact OG-OE2 2.61Å; T196-E305 PolarHBondContact N-OE2 2.72Å; T196-E305 PolarHBondContact OG1-OE2 2.68Å; L197-E305 HydrophobicContact CD1-CB 3.8Å; L197-E305 HydrophobicContact CD1-CG 4.17Å; L197-E305 HydrophobicContact CG-CB 3.9Å; Y234-E305 HydrophobicContact CD1-CG 3.96Å; Y234-E305 HydrophobicContact CD2-CG 4.08Å; Y234-E305 HydrophobicContact CE1-CG 3.63Å; Y234-E305 HydrophobicContact CE2-CB 4.33Å; Y234-E305 HydrophobicContact CE2-CG 3.74Å; Y234-E305 HydrophobicContact CG-CG 4.18Å; E305-L307 PolarHBondContact O-N 3.03Å; E305-M308 WeakPolarHBondContact O-CB 3.4Å; E305-M308 PolarHBondContact O-N 3.4Å
306K80Confident81.4Confident140 Ų14069.8 Ų69.861%0.60936%0.359SS*.G310 helixtrans-68.3-22.5-178.9-60.9-177.7-178177.80113.3S304S304-K306 VanDerWaalsContact C-N 3.28Å; S304-K306 PolarHBondContact O-N 2.83Å
307L83.3Confident82.5Confident64 Ų6465 Ų6534%0.33533%0.329SS..G310 helixtrans-91.4-7.9-177.9-82.887.6000112.8L302 S304 E305 D309 L310 Q311L302-L307 HydrophobicContact CD1-CD2 4.07Å; S304-L307 PolarHBondContact O-N 3.41Å; S304-L307 VanDerWaalsContact O-N 3.16Å; S304-L307 WeakPolarHBondContact OG-CD1 3.43Å; E305-L307 PolarHBondContact O-N 3.03Å; L307-D309 VanDerWaalsContact C-N 3.25Å; L307-D309 PolarHBondContact O-N 2.87Å; L307-L310 PolarHBondContact O-N 2.89Å; L307-L310 VanDerWaalsContact O-N 3.11Å; L307-Q311 WeakPolarHBondContact O-CG 3.32Å; L307-Q311 PolarHBondContact O-N 3.13Å
308M81.6Confident83.3Confident1 Ų156 Ų561%0.00529%0.294CS..Hα-helixtrans-59-37.6-173.7-171.266.8-17600111.9I229 F237 E305 Q311 L312I229-M308 HydrophobicContact CD1-CB 3.64Å; I229-M308 HydrophobicContact CD1-CG 3.65Å; I229-M308 HydrophobicContact CG2-CB 4.33Å; I229-M308 HydrophobicContact CG2-CG 4.2Å; F237-M308 HydrophobicContact CB-CE 4.01Å; F237-M308 HydrophobicContact CD1-CE 3.63Å; F237-M308 HydrophobicContact CD1-SD 4.31Å; F237-M308 HydrophobicContact CD2-CE 3.88Å; F237-M308 HydrophobicContact CE1-CE 4.04Å; F237-M308 HydrophobicContact CE2-CE 4.25Å; F237-M308 HydrophobicContact CG-CE 3.54Å; F237-M308 HydrophobicContact CZ-CE 4.32Å; E305-M308 WeakPolarHBondContact O-CB 3.4Å; E305-M308 PolarHBondContact O-N 3.4Å; M308-Q311 PolarHBondContact O-N 2.93Å; M308-L312 HydrophobicContact CE-CD1 4.15Å; M308-L312 HydrophobicContact CE-CD2 3.88Å; M308-L312 HydrophobicContact CE-CG 3.99Å; M308-L312 HydrophobicContact CG-CD1 4.27Å; M308-L312 HydrophobicContact CG-CG 4.42Å; M308-L312 WeakPolarHBondContact O-CB 3.37Å; M308-L312 VanDerWaalsContact O-CG 3.25Å; M308-L312 WeakPolarHBondContact O-CG 3.33Å; M308-L312 PolarHBondContact O-N 2.78Å
309D81.1Confident84Confident45 Ų4550.6 Ų50.624%0.24127%0.27CS..Hα-helixtrans-61.2-48.8176-80.8-55000112I229 L307 Q311 L312 S313I229-D309 HydrophobicContact CD1-CB 3.9Å; I229-D309 WeakPolarHBondContact CD1-OD1 3.44Å; I229-D309 WeakPolarHBondContact CD1-OD2 3.26Å; I229-D309 WeakPolarHBondContact CG1-OD1 3.31Å; L307-D309 VanDerWaalsContact C-N 3.25Å; L307-D309 PolarHBondContact O-N 2.87Å; D309-Q311 VanDerWaalsContact C-N 3.31Å; D309-Q311 PolarHBondContact O-N 3.35Å; D309-L312 PolarHBondContact O-N 2.77Å; D309-S313 PolarHBondContact O-N 3.04Å; D309-S313 VanDerWaalsContact O-N 3.08Å
310L83.4Confident84.8Confident115 Ų11552 Ų5260%0.60226%0.264SS*.Hα-helixtrans-63.8-40.2179.2-74.682.5000110.6L307 S313 D314L307-L310 PolarHBondContact O-N 2.89Å; L307-L310 VanDerWaalsContact O-N 3.11Å; L310-S313 PolarHBondContact O-N 3.19Å; L310-S313 PolarHBondContact O-OG 3.44Å; L310-D314 PolarHBondContact O-N 3.5Å; L310-D314 VanDerWaalsContact O-N 3.16Å
311Q84.5Confident85.4Confident20 Ų2046 Ų469%0.09324%0.239CC..Hα-helixtrans-66.5-41.6177.6-71.9-178.5-20.500112.7L302 L307 M308 D309 S313 D314 F317L302-Q311 PolarHBondContact O-NE2 2.95Å; L302-Q311 PolarHBondContact O-OE1 2.9Å; L307-Q311 WeakPolarHBondContact O-CG 3.32Å; L307-Q311 PolarHBondContact O-N 3.13Å; M308-Q311 PolarHBondContact O-N 2.93Å; D309-Q311 VanDerWaalsContact C-N 3.31Å; D309-Q311 PolarHBondContact O-N 3.35Å; Q311-S313 PolarHBondContact O-N 2.97Å; Q311-D314 PolarHBondContact O-N 2.8Å; Q311-F317 HydrophobicContact CB-CD1 3.87Å; Q311-F317 HydrophobicContact CB-CD2 4.28Å; Q311-F317 HydrophobicContact CB-CE1 3.91Å; Q311-F317 HydrophobicContact CB-CE2 4.33Å; Q311-F317 HydrophobicContact CB-CG 4.04Å; Q311-F317 HydrophobicContact CB-CZ 4.12Å; Q311-F317 WeakPolarHBondContact O-CB 3.41Å; Q311-F317 WeakPolarHBondContact O-CD1 3.35Å
312L83.1Confident85.8Confident4 Ų443.2 Ų43.22%0.02123%0.226CC..Hα-helixtrans-64.8-27.1175.5-71.8178000112.2I229 F270 M308 D309 R318I229-L312 HydrophobicContact CD1-CD1 4.04Å; F270-L312 HydrophobicContact CD1-CD2 4.33Å; F270-L312 HydrophobicContact CE1-CD2 3.57Å; F270-L312 HydrophobicContact CZ-CD2 4.49Å; M308-L312 HydrophobicContact CE-CD1 4.15Å; M308-L312 HydrophobicContact CE-CD2 3.88Å; M308-L312 HydrophobicContact CE-CG 3.99Å; M308-L312 HydrophobicContact CG-CD1 4.27Å; M308-L312 HydrophobicContact CG-CG 4.42Å; M308-L312 WeakPolarHBondContact O-CB 3.37Å; M308-L312 VanDerWaalsContact O-CG 3.25Å; M308-L312 WeakPolarHBondContact O-CG 3.33Å; M308-L312 PolarHBondContact O-N 2.78Å; D309-L312 PolarHBondContact O-N 2.77Å; L312-R318 VanDerWaalsContact O-CZ 3.25Å; L312-R318 PolarHBondContact O-NE 3.39Å; L312-R318 PolarHBondContact O-NH2 2.99Å
313S83.7Confident86.3Confident48 Ų4841.7 Ų41.734%0.33622%0.219SC..Hα-helixtrans-78.7-1817379.10000113.8L275 D309 L310 Q311 S315L275-S313 VanDerWaalsContact CD2-O 3.27Å; L275-S313 WeakPolarHBondContact CD2-O 3.49Å; D309-S313 PolarHBondContact O-N 3.04Å; D309-S313 VanDerWaalsContact O-N 3.08Å; L310-S313 PolarHBondContact O-N 3.19Å; L310-S313 PolarHBondContact O-OG 3.44Å; Q311-S313 PolarHBondContact O-N 2.97Å; S313-S315 PolarHBondContact O-N 2.81Å
314D85.6Confident86.8Confident60 Ų6042 Ų4232%0.32122%0.218SC..  trans-80.1120.2179.2-179.617000111.9L310 Q311 N316 F317 R318L310-D314 PolarHBondContact O-N 3.5Å; L310-D314 VanDerWaalsContact O-N 3.16Å; Q311-D314 PolarHBondContact O-N 2.8Å; D314-N316 VanDerWaalsContact C-N 3.29Å; D314-N316 PolarHBondContact O-N 2.91Å; D314-N316 PolarHBondContact OD1-N 3.22Å; D314-F317 HydrophobicContact CB-CB 3.99Å; D314-F317 PolarHBondContact O-N 2.88Å; D314-F317 PolarHBondContact OD2-N 3.32Å; D314-R318 PolarHBondContact O-N 3.3Å
315S86.9Confident87.4Confident19 Ų1939.6 Ų39.613%0.13320%0.201CC..Hα-helixtrans-54.4-40.5172.158.90000113.9S313 R318 R319 P368S313-S315 PolarHBondContact O-N 2.81Å; S315-R318 PolarHBondContact O-N 3.34Å; S315-R319 WeakPolarHBondContact O-CG 3.27Å; S315-R319 PolarHBondContact O-N 3.4Å; S315-R319 VanDerWaalsContact O-N 3.09Å; S315-P368 WeakPolarHBondContact CB-O 3.43Å
316N87.3Confident88.1Confident81 Ų8139.4 Ų39.443%0.43320%0.2SC..Hα-helixtrans-69.7-46.5-178.2-67.4-54.4000110D314 R318 R319 H320D314-N316 VanDerWaalsContact C-N 3.29Å; D314-N316 PolarHBondContact O-N 2.91Å; D314-N316 PolarHBondContact OD1-N 3.22Å; N316-R318 VanDerWaalsContact C-N 3.3Å; N316-R318 PolarHBondContact O-N 3.26Å; N316-R319 WeakPolarHBondContact O-CB 3.48Å; N316-R319 PolarHBondContact O-N 2.76Å; N316-H320 VanDerWaalsContact C-ND1 3.28Å; N316-H320 PolarHBondContact O-CE1 2.92Å; N316-H320 PolarHBondContact O-N 3.22Å; N316-H320 PolarHBondContact O-ND1 3.34Å
317F89.2Confident88.8Confident10 Ų1036.8 Ų36.84%0.04419%0.192CC..Hα-helixtrans-52.1-47.6175.1-175.9-104.8000112.3F237 W238 F301 Q311 D314 R319 H320 I321F237-F317 HydrophobicContact CE1-CE1 4.16Å; F237-F317 AromaticContact CE1-CZ 3.63Å; F237-F317 HydrophobicContact CE1-CZ 3.63Å; F237-F317 HydrophobicContact CE2-CE1 4.4Å; F237-F317 AromaticContact CZ-CE1 3.6Å; F237-F317 HydrophobicContact CZ-CE1 3.6Å; F237-F317 AromaticContact CZ-CZ 3.45Å; F237-F317 HydrophobicContact CZ-CZ 3.45Å; F237-F317 VanDerWaalsContact CZ-CZ 3.45Å; W238-F317 HydrophobicContact CH2-CE2 4.21Å; W238-F317 HydrophobicContact CH2-CZ 4.19Å; F301-F317 HydrophobicContact CD1-CD2 4.29Å; F301-F317 AromaticContact CD1-CE2 3.97Å; F301-F317 HydrophobicContact CD1-CE2 3.97Å; F301-F317 HydrophobicContact CE1-CD2 4.34Å; F301-F317 HydrophobicContact CE1-CE2 4.23Å; Q311-F317 HydrophobicContact CB-CD1 3.87Å; Q311-F317 HydrophobicContact CB-CD2 4.28Å; Q311-F317 HydrophobicContact CB-CE1 3.91Å; Q311-F317 HydrophobicContact CB-CE2 4.33Å; Q311-F317 HydrophobicContact CB-CG 4.04Å; Q311-F317 HydrophobicContact CB-CZ 4.12Å; Q311-F317 WeakPolarHBondContact O-CB 3.41Å; Q311-F317 WeakPolarHBondContact O-CD1 3.35Å; D314-F317 HydrophobicContact CB-CB 3.99Å; D314-F317 PolarHBondContact O-N 2.88Å; D314-F317 PolarHBondContact OD2-N 3.32Å; F317-R319 PolarHBondContact O-N 3.17Å; F317-H320 WeakPolarHBondContact O-CB 3.49Å; F317-H320 PolarHBondContact O-N 3.24Å; F317-I321 HydrophobicContact CE1-CG1 4.33Å; F317-I321 HydrophobicContact CZ-CD1 4.46Å; F317-I321 HydrophobicContact CZ-CG1 4.38Å; F317-I321 WeakPolarHBondContact O-CG1 3.46Å; F317-I321 PolarHBondContact O-N 3.47Å
318R89.5Confident89.3Confident8 Ų834.1 Ų34.13%0.0318%0.178CC..Hα-helixtrans-58.6-44.9174.6-68.3-174.8-176.2-136.8-18.7113F270 F273 L312 D314 S315 N316 H320 I321 L322F270-R318 HydrophobicContact CD1-CG 4.44Å; F270-R318 HydrophobicContact CE1-CG 4.15Å; F270-R318 HydrophobicContact CZ-CG 4.46Å; F270-R318 PolarHBondContact O-NH1 2.96Å; F273-R318 PolarHBondContact O-NH1 3.39Å; F273-R318 PolarHBondContact O-NH2 3.43Å; L312-R318 VanDerWaalsContact O-CZ 3.25Å; L312-R318 PolarHBondContact O-NE 3.39Å; L312-R318 PolarHBondContact O-NH2 2.99Å; D314-R318 PolarHBondContact O-N 3.3Å; S315-R318 PolarHBondContact O-N 3.34Å; N316-R318 VanDerWaalsContact C-N 3.3Å; N316-R318 PolarHBondContact O-N 3.26Å; R318-H320 VanDerWaalsContact C-N 3.32Å; R318-H320 PolarHBondContact O-N 3.36Å; R318-I321 PolarHBondContact O-N 2.8Å; R318-L322 WeakPolarHBondContact O-CB 3.27Å; R318-L322 VanDerWaalsContact O-CG 3.26Å; R318-L322 WeakPolarHBondContact O-CG 3.43Å; R318-L322 PolarHBondContact O-N 3.04Å
319R91.4Very high89.9Confident23 Ų2334.2 Ų34.29%0.08718%0.178CC..Hα-helixtrans-58.4-43.9176.5-73.1170.7179.4-166.3-9.1111.6S315 N316 F317 I321 L322 L323 L364 T367 P368 P369 F374S315-R319 WeakPolarHBondContact O-CG 3.27Å; S315-R319 PolarHBondContact O-N 3.4Å; S315-R319 VanDerWaalsContact O-N 3.09Å; N316-R319 WeakPolarHBondContact O-CB 3.48Å; N316-R319 PolarHBondContact O-N 2.76Å; F317-R319 PolarHBondContact O-N 3.17Å; R319-I321 VanDerWaalsContact C-N 3.34Å; R319-I321 PolarHBondContact O-N 3.02Å; R319-L322 PolarHBondContact O-N 3.03Å; R319-L323 WeakPolarHBondContact O-CB 3.47Å; R319-L323 WeakPolarHBondContact O-CG 3.41Å; R319-L323 PolarHBondContact O-N 3.27Å; R319-L364 HydrophobicContact CG-CD2 4.2Å; R319-T367 HydrophobicContact CG-CG2 4.12Å; R319-T367 PolarHBondContact NH2-O 3.49Å; R319-P368 VanDerWaalsContact NH2-C 3.3Å; R319-P368 PolarHBondContact NH2-O 3.36Å; R319-P369 PolarHBondContact NH2-O 3.38Å; R319-F374 HydrophobicContact CB-CE1 4.17Å; R319-F374 HydrophobicContact CB-CZ 4.21Å; R319-F374 HydrophobicContact CG-CD1 4.45Å; R319-F374 HydrophobicContact CG-CE1 3.96Å; R319-F374 HydrophobicContact CG-CZ 4.28Å
320H92.3Very high90.4Very high96 Ų9633.8 Ų33.844%0.44418%0.175SC..Hα-helixtrans-58.5-45.5177.9-64109.7000111.8F301 N316 F317 R318 Q324F301-H320 HydrophobicContact CE1-CB 4.25Å; F301-H320 HydrophobicContact CZ-CB 4.31Å; N316-H320 VanDerWaalsContact C-ND1 3.28Å; N316-H320 PolarHBondContact O-CE1 2.92Å; N316-H320 PolarHBondContact O-N 3.22Å; N316-H320 PolarHBondContact O-ND1 3.34Å; F317-H320 WeakPolarHBondContact O-CB 3.49Å; F317-H320 PolarHBondContact O-N 3.24Å; R318-H320 VanDerWaalsContact C-N 3.32Å; R318-H320 PolarHBondContact O-N 3.36Å; H320-Q324 WeakPolarHBondContact O-CG 3.4Å; H320-Q324 PolarHBondContact O-N 2.97Å
321I92.6Very high90.7Very high4 Ų430.6 Ų30.62%0.02116%0.155CC..Hα-helixtrans-69.3-46.2-179.5-57.8-62000111.5F237 F270 F301 F317 R318 R319 L323 Q324 Y325F237-I321 HydrophobicContact CE1-CD1 4.39Å; F237-I321 HydrophobicContact CE2-CD1 4.4Å; F237-I321 HydrophobicContact CE2-CG1 4.27Å; F237-I321 HydrophobicContact CE2-CG2 4.35Å; F237-I321 HydrophobicContact CZ-CD1 3.65Å; F237-I321 HydrophobicContact CZ-CG1 3.79Å; F270-I321 HydrophobicContact CE2-CB 4.25Å; F270-I321 HydrophobicContact CE2-CG2 3.91Å; F270-I321 HydrophobicContact CZ-CB 4.37Å; F270-I321 HydrophobicContact CZ-CG2 4.24Å; F301-I321 HydrophobicContact CZ-CD1 4.43Å; F317-I321 HydrophobicContact CE1-CG1 4.33Å; F317-I321 HydrophobicContact CZ-CD1 4.46Å; F317-I321 HydrophobicContact CZ-CG1 4.38Å; F317-I321 WeakPolarHBondContact O-CG1 3.46Å; F317-I321 PolarHBondContact O-N 3.47Å; R318-I321 PolarHBondContact O-N 2.8Å; R319-I321 VanDerWaalsContact C-N 3.34Å; R319-I321 PolarHBondContact O-N 3.02Å; I321-L323 VanDerWaalsContact C-N 3.3Å; I321-L323 PolarHBondContact O-N 2.98Å; I321-Q324 WeakPolarHBondContact O-CB 3.42Å; I321-Q324 PolarHBondContact O-N 2.91Å; I321-Q324 VanDerWaalsContact O-N 3.12Å; I321-Y325 HydrophobicContact CG2-CD2 4.1Å; I321-Y325 HydrophobicContact CG2-CE2 3.89Å; I321-Y325 WeakPolarHBondContact O-CD2 3.32Å; I321-Y325 PolarHBondContact O-N 3.22Å
322L93.9Very high90.9Very high1 Ų129.9 Ų29.91%0.00515%0.152CC..Hα-helixtrans-62.6-37.5177.8-67.9173.1000111.6L267 F270 R318 R319 Y325 L326 V360 L363 L364L267-L322 HydrophobicContact CD2-CD2 3.93Å; F270-L322 HydrophobicContact CD2-CD2 4.1Å; F270-L322 HydrophobicContact CE2-CD2 4.44Å; R318-L322 WeakPolarHBondContact O-CB 3.27Å; R318-L322 VanDerWaalsContact O-CG 3.26Å; R318-L322 WeakPolarHBondContact O-CG 3.43Å; R318-L322 PolarHBondContact O-N 3.04Å; R319-L322 PolarHBondContact O-N 3.03Å; L322-Y325 WeakPolarHBondContact O-CB 3.41Å; L322-Y325 PolarHBondContact O-N 3.36Å; L322-L326 PolarHBondContact O-N 2.91Å; L322-L326 VanDerWaalsContact O-N 3.12Å; L322-V360 HydrophobicContact CB-CG1 3.98Å; L322-V360 HydrophobicContact CD2-CB 4.48Å; L322-V360 HydrophobicContact CD2-CG1 3.99Å; L322-V360 HydrophobicContact CD2-CG2 4.24Å; L322-V360 WeakPolarHBondContact O-CG1 3.08Å; L322-L363 HydrophobicContact CD1-CB 3.95Å; L322-L363 HydrophobicContact CD2-CB 4.28Å; L322-L363 HydrophobicContact CD2-CD1 4.15Å; L322-L364 HydrophobicContact CB-CD1 4.4Å; L322-L364 HydrophobicContact CB-CD2 3.67Å; L322-L364 HydrophobicContact CB-CG 3.9Å; L322-L364 HydrophobicContact CD1-CD2 3.76Å; L322-L364 HydrophobicContact CD1-CG 3.94Å; L322-L364 HydrophobicContact CG-CD2 4.38Å
323L95.3Very high91.1Very high43 Ų4334.1 Ų34.123%0.22517%0.17CC..Hα-helixtrans-63.3-42.5171.6-77.5173.7000112.3R319 I321 Y325 L326 I327 F374 V378R319-L323 WeakPolarHBondContact O-CB 3.47Å; R319-L323 WeakPolarHBondContact O-CG 3.41Å; R319-L323 PolarHBondContact O-N 3.27Å; I321-L323 VanDerWaalsContact C-N 3.3Å; I321-L323 PolarHBondContact O-N 2.98Å; L323-Y325 VanDerWaalsContact C-N 3.27Å; L323-Y325 PolarHBondContact O-N 2.89Å; L323-L326 PolarHBondContact O-N 2.57Å; L323-L326 VanDerWaalsContact O-N 3.14Å; L323-I327 WeakPolarHBondContact O-CG1 3.4Å; L323-I327 PolarHBondContact O-N 2.84Å; L323-F374 HydrophobicContact CD1-CE1 4.36Å; L323-F374 HydrophobicContact CD1-CZ 3.91Å; L323-F374 HydrophobicContact CD2-CE1 4.42Å; L323-F374 HydrophobicContact CG-CE1 4.41Å; L323-F374 HydrophobicContact CG-CZ 4.44Å; L323-V378 HydrophobicContact CD2-CB 4.27Å; L323-V378 HydrophobicContact CD2-CG1 3.63Å; L323-V378 HydrophobicContact CD2-CG2 3.55Å
324Q94.6Very high91.1Very high42 Ų4232.9 Ų32.920%0.19617%0.165CC..Hα-helixtrans-60.1-38.1175.8-75.4178.712.400111.8F244 H320 I321 L328F244-Q324 HydrophobicContact CD1-CB 3.98Å; F244-Q324 HydrophobicContact CD2-CB 4.31Å; F244-Q324 VanDerWaalsContact CD2-OE1 3.24Å; F244-Q324 HydrophobicContact CE1-CB 4.11Å; F244-Q324 HydrophobicContact CE2-CB 4.43Å; F244-Q324 HydrophobicContact CG-CB 4.11Å; F244-Q324 HydrophobicContact CZ-CB 4.34Å; H320-Q324 WeakPolarHBondContact O-CG 3.4Å; H320-Q324 PolarHBondContact O-N 2.97Å; I321-Q324 WeakPolarHBondContact O-CB 3.42Å; I321-Q324 PolarHBondContact O-N 2.91Å; I321-Q324 VanDerWaalsContact O-N 3.12Å; Q324-L328 VanDerWaalsContact O-CB 3.25Å; Q324-L328 WeakPolarHBondContact O-CB 3.4Å; Q324-L328 PolarHBondContact O-N 2.66Å
325Y95.4Very high90.7Very high0 Ų038.2 Ų38.20%019%0.188CC..Hα-helixtrans-59.5-49.1171.1-84.5-71.7000112.2L240 F244 F259 S263 L267 I321 L322 L323 I327 L328 F329L240-Y325 WeakPolarHBondContact CD1-OH 3.44Å; F244-Y325 AromaticContact CE1-CD1 3.93Å; F244-Y325 HydrophobicContact CE1-CD1 3.93Å; F244-Y325 HydrophobicContact CE1-CD2 4.44Å; F244-Y325 HydrophobicContact CE1-CE1 4.16Å; F244-Y325 HydrophobicContact CE1-CG 4.08Å; F244-Y325 HydrophobicContact CE2-CE2 4.43Å; F244-Y325 AromaticContact CZ-CD1 3.83Å; F244-Y325 HydrophobicContact CZ-CD1 3.83Å; F244-Y325 AromaticContact CZ-CD2 3.8Å; F244-Y325 HydrophobicContact CZ-CD2 3.8Å; F244-Y325 AromaticContact CZ-CE1 3.72Å; F244-Y325 HydrophobicContact CZ-CE1 3.72Å; F244-Y325 AromaticContact CZ-CE2 3.69Å; F244-Y325 HydrophobicContact CZ-CE2 3.69Å; F244-Y325 AromaticContact CZ-CG 3.86Å; F244-Y325 HydrophobicContact CZ-CG 3.86Å; F244-Y325 AromaticContact CZ-CZ 3.65Å; F259-Y325 HydrophobicContact CE2-CE1 4.26Å; F259-Y325 HydrophobicContact CZ-CD1 4.39Å; F259-Y325 AromaticContact CZ-CE1 3.93Å; F259-Y325 HydrophobicContact CZ-CE1 3.93Å; S263-Y325 WeakPolarHBondContact CA-OH 3.3Å; S263-Y325 WeakPolarHBondContact CB-OH 3.38Å; S263-Y325 WeakPolarHBondContact OG-CE1 3.46Å; S263-Y325 PolarHBondContact OG-OH 3.22Å; S263-Y325 VanDerWaalsContact OG-OH 3.06Å; L267-Y325 HydrophobicContact CD2-CD2 4.48Å; L267-Y325 HydrophobicContact CD2-CE2 4.25Å; I321-Y325 HydrophobicContact CG2-CD2 4.1Å; I321-Y325 HydrophobicContact CG2-CE2 3.89Å; I321-Y325 WeakPolarHBondContact O-CD2 3.32Å; I321-Y325 PolarHBondContact O-N 3.22Å; L322-Y325 WeakPolarHBondContact O-CB 3.41Å; L322-Y325 PolarHBondContact O-N 3.36Å; L323-Y325 VanDerWaalsContact C-N 3.27Å; L323-Y325 PolarHBondContact O-N 2.89Å; Y325-I327 PolarHBondContact O-N 3.45Å; Y325-L328 PolarHBondContact O-N 3.05Å; Y325-F329 HydrophobicContact CD1-CE1 4.1Å; Y325-F329 HydrophobicContact CD1-CE2 4.22Å; Y325-F329 AromaticContact CD1-CZ 3.63Å; Y325-F329 HydrophobicContact CD1-CZ 3.63Å; Y325-F329 HydrophobicContact CE1-CZ 4.41Å; Y325-F329 HydrophobicContact CG-CZ 4.43Å; Y325-F329 WeakPolarHBondContact O-CB 3.35Å; Y325-F329 WeakPolarHBondContact O-CD2 3.45Å; Y325-F329 WeakPolarHBondContact O-CG 3.36Å; Y325-F329 PolarHBondContact O-N 2.91Å
326L95.6Very high90.4Very high4 Ų438.2 Ų38.22%0.02119%0.187CC..Hα-helixtrans-62.2-44.7-180-66.7179000112.3L322 L323 L328 F329 Q330 T357 V360 Y361 L364 V378 L382L322-L326 PolarHBondContact O-N 2.91Å; L322-L326 VanDerWaalsContact O-N 3.12Å; L323-L326 PolarHBondContact O-N 2.57Å; L323-L326 VanDerWaalsContact O-N 3.14Å; L326-L328 VanDerWaalsContact C-N 3.34Å; L326-L328 PolarHBondContact O-N 3.05Å; L326-F329 PolarHBondContact O-N 3.48Å; L326-Q330 WeakPolarHBondContact O-CB 3.25Å; L326-Q330 PolarHBondContact O-N 3.1Å; L326-T357 HydrophobicContact CD2-CG2 3.99Å; L326-V360 HydrophobicContact CD1-CG1 4.23Å; L326-V360 HydrophobicContact CD2-CB 4.19Å; L326-V360 HydrophobicContact CD2-CG1 3.69Å; L326-V360 HydrophobicContact CG-CG1 3.69Å; L326-Y361 HydrophobicContact CD1-CD1 4.49Å; L326-Y361 HydrophobicContact CD1-CE1 4.03Å; L326-Y361 HydrophobicContact CD1-CE2 4.46Å; L326-Y361 HydrophobicContact CD2-CD2 4.13Å; L326-Y361 HydrophobicContact CD2-CE2 3.81Å; L326-L364 HydrophobicContact CD1-CD1 3.57Å; L326-V378 HydrophobicContact CD1-CG1 3.65Å; L326-L382 HydrophobicContact CB-CD1 3.93Å; L326-L382 HydrophobicContact CD1-CD1 4.18Å
327I94.8Very high89.8Confident84 Ų8440.6 Ų40.643%0.43119%0.193SC..Hα-helixtrans-62.1-43.5177.1-65.8165.6000110.4L323 Y325 Y331 L382L323-I327 WeakPolarHBondContact O-CG1 3.4Å; L323-I327 PolarHBondContact O-N 2.84Å; Y325-I327 PolarHBondContact O-N 3.45Å; I327-Y331 WeakPolarHBondContact O-CB 3.12Å; I327-Y331 PolarHBondContact O-N 3.22Å; I327-L382 HydrophobicContact CG1-CD2 4.33Å
328L94.1Very high88.9Confident8 Ų845.3 Ų45.34%0.04221%0.214CC..Hα-helixtrans-61.8-47.1176.4176.463.8000111.3F244 P247 F259 Q324 Y325 L326 Y331 L332F244-L328 HydrophobicContact CD1-CB 4.12Å; F244-L328 HydrophobicContact CD1-CD2 3.72Å; F244-L328 HydrophobicContact CD1-CG 4.48Å; F244-L328 HydrophobicContact CE1-CB 4.26Å; F244-L328 HydrophobicContact CE1-CD2 3.7Å; P247-L328 HydrophobicContact CB-CD1 3.45Å; P247-L328 VanDerWaalsContact CB-CD1 3.45Å; F259-L328 HydrophobicContact CE1-CD2 4.46Å; F259-L328 HydrophobicContact CE2-CD2 3.83Å; F259-L328 HydrophobicContact CZ-CD2 3.57Å; Q324-L328 VanDerWaalsContact O-CB 3.25Å; Q324-L328 WeakPolarHBondContact O-CB 3.4Å; Q324-L328 PolarHBondContact O-N 2.66Å; Y325-L328 PolarHBondContact O-N 3.05Å; L326-L328 VanDerWaalsContact C-N 3.34Å; L326-L328 PolarHBondContact O-N 3.05Å; L328-Y331 PolarHBondContact O-N 3.13Å; L328-L332 HydrophobicContact CD1-CD1 4.09Å; L328-L332 HydrophobicContact CD1-CG 4.05Å; L328-L332 HydrophobicContact CG-CD1 3.98Å; L328-L332 HydrophobicContact CG-CG 4.33Å; L328-L332 WeakPolarHBondContact O-CB 3.27Å; L328-L332 VanDerWaalsContact O-CG 3.31Å; L328-L332 WeakPolarHBondContact O-CG 3.18Å; L328-L332 PolarHBondContact O-N 3.25Å
329F93.6Very high88.4Confident4 Ų447 Ų472%0.01822%0.221CC..Hα-helixtrans-63.6-42.4-179.8-65.6-20.1000112.2F259 Y325 L326 Y331 L332 K333 W352 I353 T356 T357 V360F259-F329 HydrophobicContact CE1-CE1 4.44Å; F259-F329 HydrophobicContact CZ-CE1 4.38Å; Y325-F329 HydrophobicContact CD1-CE1 4.1Å; Y325-F329 HydrophobicContact CD1-CE2 4.22Å; Y325-F329 AromaticContact CD1-CZ 3.63Å; Y325-F329 HydrophobicContact CD1-CZ 3.63Å; Y325-F329 HydrophobicContact CE1-CZ 4.41Å; Y325-F329 HydrophobicContact CG-CZ 4.43Å; Y325-F329 WeakPolarHBondContact O-CB 3.35Å; Y325-F329 WeakPolarHBondContact O-CD2 3.45Å; Y325-F329 WeakPolarHBondContact O-CG 3.36Å; Y325-F329 PolarHBondContact O-N 2.91Å; L326-F329 PolarHBondContact O-N 3.48Å; F329-Y331 VanDerWaalsContact C-N 3.35Å; F329-L332 PolarHBondContact O-N 2.94Å; F329-K333 WeakPolarHBondContact O-CB 3.42Å; F329-K333 PolarHBondContact O-N 3.35Å; F329-W352 HydrophobicContact CE1-CH2 4.4Å; F329-W352 AromaticContact CE1-CZ3 3.94Å; F329-W352 HydrophobicContact CE1-CZ3 3.94Å; F329-W352 HydrophobicContact CZ-CH2 4.29Å; F329-W352 HydrophobicContact CZ-CZ3 4.13Å; F329-I353 HydrophobicContact CB-CG2 3.72Å; F329-I353 HydrophobicContact CD1-CG1 4.29Å; F329-I353 HydrophobicContact CD1-CG2 3.97Å; F329-I353 HydrophobicContact CD2-CG2 4.3Å; F329-I353 HydrophobicContact CG-CG2 3.75Å; F329-T356 HydrophobicContact CE2-CG2 3.82Å; F329-T356 HydrophobicContact CZ-CG2 3.68Å; F329-T357 VanDerWaalsContact CD2-OG1 3.28Å; F329-T357 WeakPolarHBondContact CD2-OG1 3.44Å; F329-V360 HydrophobicContact CE2-CG2 4.38Å
330Q91.6Very high87.6Confident36 Ų3649.5 Ų49.517%0.16824%0.243CC..Hα-helixtrans-62.5-43173.9-175174.61.500111.3L326 G334 L382L326-Q330 WeakPolarHBondContact O-CB 3.25Å; L326-Q330 PolarHBondContact O-N 3.1Å; Q330-G334 WeakPolarHBondContact O-CA 3.31Å; Q330-G334 PolarHBondContact O-N 3.42Å; Q330-L382 PolarHBondContact NE2-O 3.29Å; Q330-L382 VanDerWaalsContact OE1-CB 3.27Å
331Y90.7Very high86.6Confident47 Ų4750.8 Ų50.818%0.18426%0.263CS..Hα-helixtrans-60.9-47.9174.6171.8-99.9000111.6F180 P247 I327 L328 F329 K333 G334 V336 K339F180-Y331 HydrophobicContact CE2-CE2 4.49Å; F180-Y331 AromaticContact CE2-CZ 3.99Å; F180-Y331 HydrophobicContact CZ-CD2 4.32Å; F180-Y331 AromaticContact CZ-CE1 3.99Å; F180-Y331 HydrophobicContact CZ-CE1 3.99Å; F180-Y331 AromaticContact CZ-CE2 3.65Å; F180-Y331 HydrophobicContact CZ-CE2 3.65Å; F180-Y331 AromaticContact CZ-CZ 3.45Å; F180-Y331 VanDerWaalsContact CZ-CZ 3.45Å; P247-Y331 HydrophobicContact CB-CD1 3.64Å; P247-Y331 HydrophobicContact CB-CE1 3.64Å; P247-Y331 HydrophobicContact CG-CD1 3.84Å; P247-Y331 HydrophobicContact CG-CE1 3.59Å; I327-Y331 WeakPolarHBondContact O-CB 3.12Å; I327-Y331 PolarHBondContact O-N 3.22Å; L328-Y331 PolarHBondContact O-N 3.13Å; F329-Y331 VanDerWaalsContact C-N 3.35Å; Y331-K333 VanDerWaalsContact C-N 3.32Å; Y331-K333 PolarHBondContact O-N 3.17Å; Y331-G334 PolarHBondContact O-N 3.38Å; Y331-V336 HydrophobicContact CE2-CG2 4.32Å; Y331-K339 PolarHBondContact O-NZ 3.49Å; Y331-K339 WeakPolarHBondContact OH-CE 3.27Å
332L89Confident85.6Confident6 Ų655.1 Ų55.13%0.03129%0.293CS..Hα-helixtrans-62.6-38.1-176.8-72.5176.7000112.2C250 Y251 W256 L328 F329 L345 I353C250-L332 HydrophobicContact CB-CD1 4.26Å; C250-L332 HydrophobicContact CB-CD2 3.99Å; Y251-L332 HydrophobicContact CE1-CD2 4.4Å; Y251-L332 HydrophobicContact CE2-CD2 3.94Å; Y251-L332 PolarHBondContact OH-O 3.29Å; W256-L332 HydrophobicContact CZ3-CD1 4.05Å; L328-L332 HydrophobicContact CD1-CD1 4.09Å; L328-L332 HydrophobicContact CD1-CG 4.05Å; L328-L332 HydrophobicContact CG-CD1 3.98Å; L328-L332 HydrophobicContact CG-CG 4.33Å; L328-L332 WeakPolarHBondContact O-CB 3.27Å; L328-L332 VanDerWaalsContact O-CG 3.31Å; L328-L332 WeakPolarHBondContact O-CG 3.18Å; L328-L332 PolarHBondContact O-N 3.25Å; F329-L332 PolarHBondContact O-N 2.94Å; L332-L345 HydrophobicContact CB-CD1 4.15Å; L332-I353 HydrophobicContact CB-CD1 4.34Å; L332-I353 HydrophobicContact CD1-CD1 4.28Å
333K86.6Confident84.9Confident93 Ų9356.2 Ų56.240%0.40430%0.301SS..Hα-helixtrans-78.5-30.3175.4-73.2-175.1155.6-152.70114.1F329 Y331 I353 E354F329-K333 WeakPolarHBondContact O-CB 3.42Å; F329-K333 PolarHBondContact O-N 3.35Å; Y331-K333 VanDerWaalsContact C-N 3.32Å; Y331-K333 PolarHBondContact O-N 3.17Å; K333-I353 HydrophobicContact CD-CG2 4.08Å; K333-I353 HydrophobicContact CG-CG2 4.36Å; K333-E354 IonicContact NZ-OE1 3.84Å; K333-E354 PolarHBondContact NZ-OE1 3.01Å
334G83.9Confident84.3Confident21 Ų2159 Ų5922%0.21632%0.319CS..SBendtrans-69.7140.8-174.500000113.4Q330 Y331 K339Q330-G334 WeakPolarHBondContact O-CA 3.31Å; Q330-G334 PolarHBondContact O-N 3.42Å; Y331-G334 PolarHBondContact O-N 3.38Å; G334-K339 PolarHBondContact O-NZ 3.49Å
335Q77.2Confident83.8Confident172 Ų17258.2 Ų58.280%0.80432%0.316SS*.  trans-80.2129.1169-64.8-169.4-7.100109.9N389 N393Q335-N389 PolarHBondContact O-ND2 3.45Å; Q335-N393 PolarHBondContact O-ND2 3.47Å
336V79.4Confident83.5Confident20 Ų2062.9 Ų62.912%0.12134%0.341CS..  trans-131.5126.8178.4178.50000107.5Y331 F338 K339Y331-V336 HydrophobicContact CE2-CG2 4.32Å; V336-F338 PolarHBondContact O-N 3.43Å; V336-K339 HydrophobicContact CB-CD 3.87Å; V336-K339 HydrophobicContact CB-CG 3.89Å; V336-K339 HydrophobicContact CG2-CD 4.21Å; V336-K339 WeakPolarHBondContact O-CB 3.36Å; V336-K339 PolarHBondContact O-N 2.87Å
337K74.8Confident83.2Confident131 Ų13169.5 Ų69.557%0.5738%0.376SS*.THydrogen-bonded Turntrans-53.9-30.8-173.2-178.9171.1-178.5173.60115N393K337-N393 HydrophobicContact CB-CB 4.48Å; K337-N393 WeakPolarHBondContact CB-OD1 3.44Å; K337-N393 VanDerWaalsContact CD-O 3.26Å; K337-N393 WeakPolarHBondContact CD-O 3.39Å; K337-N393 PolarHBondContact N-OD1 2.91Å; K337-N393 PolarHBondContact NZ-O 2.71Å
338F71.9Confident83Confident108 Ų10872 Ų7247%0.47439%0.391SS..THydrogen-bonded Turntrans-99.87.2-177.4-62-80.8000114L176 V336L176-F338 WeakPolarHBondContact O-CD2 3.15Å; L176-F338 WeakPolarHBondContact O-CE2 3.49Å; V336-F338 PolarHBondContact O-N 3.43Å
339K78.6Confident82.8Confident43 Ų4373 Ų7319%0.18740%0.395CS..SBendtrans-69.2141.2170.5-83.6174.8179-168.50110.5Y251 Y331 G334 V336Y251-K339 PolarHBondContact OH-NZ 3.22Å; Y331-K339 PolarHBondContact O-NZ 3.49Å; Y331-K339 WeakPolarHBondContact OH-CE 3.27Å; G334-K339 PolarHBondContact O-NZ 3.49Å; V336-K339 HydrophobicContact CB-CD 3.87Å; V336-K339 HydrophobicContact CB-CG 3.89Å; V336-K339 HydrophobicContact CG2-CD 4.21Å; V336-K339 WeakPolarHBondContact O-CB 3.36Å; V336-K339 PolarHBondContact O-N 2.87Å
340S74.4Confident82.6Confident76 Ų7674.3 Ų74.353%0.53141%0.405SS..  trans-65.9146.9173.3-54.90000110.9S342 C343S340-S342 PolarHBondContact O-N 3Å; S340-C343 WeakPolarHBondContact O-CB 3.49Å; S340-C343 PolarHBondContact O-N 3.42Å
341S70.6Confident82.7Confident124 Ų12475.2 Ų75.287%0.86742%0.419SS*.THydrogen-bonded Turntrans-61-15.1177.549.90000114.3
342S71.6Confident82.9Confident95 Ų9574.9 Ų74.966%0.66442%0.417SS*.THydrogen-bonded Turntrans-81.7-12.2174530000114.5S340 V344S340-S342 PolarHBondContact O-N 3Å; S342-V344 VanDerWaalsContact C-N 3.27Å; S342-V344 PolarHBondContact O-N 2.92Å
343C79.4Confident83.2Confident23 Ų2374.6 Ų74.616%0.15542%0.416CS..  trans-86.861.2-177.2-65.10000111.5Y251 S340Y251-C343 HydrophobicContact CD1-CB 4.03Å; Y251-C343 HydrophobicContact CD2-CB 3.9Å; Y251-C343 HydrophobicContact CE1-CB 3.87Å; Y251-C343 WeakPolarHBondContact CE1-O 3.39Å; Y251-C343 HydrophobicContact CE2-CB 3.73Å; Y251-C343 HydrophobicContact CG-CB 4.05Å; S340-C343 WeakPolarHBondContact O-CB 3.49Å; S340-C343 PolarHBondContact O-N 3.42Å
344V82.6Confident83.5Confident101 Ų10174.7 Ų74.761%0.61242%0.417SS*.  trans-112.7138.6179.8-175.70000109.3S342S342-V344 VanDerWaalsContact C-N 3.27Å; S342-V344 PolarHBondContact O-N 2.92Å
345L84.8Confident84.1Confident26 Ų2680.4 Ų80.414%0.13644%0.439CS..  trans-91145.9174.7-62.8174.9000110.5Y251 L332 Q349 I353Y251-L345 HydrophobicContact CD1-CD2 4.14Å; Y251-L345 HydrophobicContact CE1-CD2 3.85Å; Y251-L345 HydrophobicContact CE1-CG 4.15Å; L332-L345 HydrophobicContact CB-CD1 4.15Å; L345-Q349 HydrophobicContact CB-CB 4.45Å; L345-Q349 HydrophobicContact CD2-CB 4.49Å; L345-I353 HydrophobicContact CD1-CD1 3.68Å
346N88.1Confident84.9Confident99 Ų9972.5 Ų72.553%0.52940%0.402SS..  trans-78163.3170-644.3000111D348 Q349 S350N346-D348 VanDerWaalsContact C-N 3.34Å; N346-D348 PolarHBondContact O-N 3.01Å; N346-Q349 HydrophobicContact CB-CG 4.22Å; N346-Q349 PolarHBondContact O-N 3.14Å; N346-Q349 VanDerWaalsContact O-N 3.17Å; N346-S350 PolarHBondContact O-N 3.39Å; N346-S350 PolarHBondContact O-OG 3.02Å
347D89.9Confident85.6Confident142 Ų14273 Ų7376%0.75941%0.405SS*.Hα-helixtrans-59.5-42.8178.8-64.2-25.2000112.1Q349 S350 A351D347-Q349 VanDerWaalsContact C-N 3.32Å; D347-Q349 PolarHBondContact O-N 2.87Å; D347-S350 PolarHBondContact O-N 3.32Å; D347-A351 WeakPolarHBondContact O-CB 3.09Å; D347-A351 PolarHBondContact O-N 2.93Å
348D89.6Confident86.6Confident137 Ų13773.9 Ų73.973%0.73341%0.409SS*.Hα-helixtrans-61.3-39.8176.8-63.4-25.6000112.4N346 W352N346-D348 VanDerWaalsContact C-N 3.34Å; N346-D348 PolarHBondContact O-N 3.01Å; D348-W352 PolarHBondContact O-N 2.93Å
349Q89.7Confident87.7Confident28 Ų2870.8 Ų70.813%0.13140%0.397CS..Hα-helixtrans-68.1-40.4177.9-61.2-179.9-53.100110.5W256 L345 N346 D347 W352 I353W256-Q349 VanDerWaalsContact CG-NE2 3.34Å; W256-Q349 HydrophobicContact CZ2-CB 3.88Å; W256-Q349 HydrophobicContact CZ2-CG 4.09Å; L345-Q349 HydrophobicContact CB-CB 4.45Å; L345-Q349 HydrophobicContact CD2-CB 4.49Å; N346-Q349 HydrophobicContact CB-CG 4.22Å; N346-Q349 PolarHBondContact O-N 3.14Å; N346-Q349 VanDerWaalsContact O-N 3.17Å; D347-Q349 VanDerWaalsContact C-N 3.32Å; D347-Q349 PolarHBondContact O-N 2.87Å; Q349-W352 PolarHBondContact O-N 3.41Å; Q349-I353 VanDerWaalsContact O-CG1 3.28Å; Q349-I353 WeakPolarHBondContact O-CG1 3.5Å; Q349-I353 PolarHBondContact O-N 3.49Å
350S90.8Very high88.5Confident33 Ų3368.8 Ų68.823%0.23139%0.388CS..Hα-helixtrans-65.4-41.8177.9-590000111.6N346 D347 I353 E354N346-S350 PolarHBondContact O-N 3.39Å; N346-S350 PolarHBondContact O-OG 3.02Å; D347-S350 PolarHBondContact O-N 3.32Å; S350-I353 PolarHBondContact O-N 2.94Å; S350-E354 WeakPolarHBondContact O-CG 3.46Å; S350-E354 PolarHBondContact O-N 3.49Å; S350-E354 VanDerWaalsContact O-N 3.09Å
351A93.4Very high89.5Confident55 Ų5567 Ų6746%0.45537%0.37SS..Hα-helixtrans-63.3-44.4175.100000111.9D347 I353 E354 E355D347-A351 WeakPolarHBondContact O-CB 3.09Å; D347-A351 PolarHBondContact O-N 2.93Å; A351-I353 VanDerWaalsContact C-N 3.34Å; A351-I353 PolarHBondContact O-N 3.13Å; A351-E354 WeakPolarHBondContact O-CB 3.34Å; A351-E354 PolarHBondContact O-N 3.34Å; A351-E354 VanDerWaalsContact O-N 3.17Å; A351-E355 PolarHBondContact O-N 3.35Å
352W94.6Very high90.5Very high39 Ų3965.3 Ų65.315%0.14835%0.349CS..Hα-helixtrans-61.7-41175.7179.387.5000112.1W256 F259 L260 F329 D348 Q349 E354 E355 T356W256-W352 AromaticContact CH2-CE3 3.98Å; W256-W352 HydrophobicContact CH2-CE3 3.98Å; W256-W352 AromaticContact CH2-CZ3 3.94Å; W256-W352 HydrophobicContact CH2-CZ3 3.94Å; W256-W352 AromaticContact CZ2-CE3 3.84Å; W256-W352 HydrophobicContact CZ2-CE3 3.84Å; W256-W352 HydrophobicContact CZ2-CZ3 4.18Å; F259-W352 HydrophobicContact CD1-CH2 4.46Å; F259-W352 AromaticContact CE1-CH2 3.87Å; F259-W352 HydrophobicContact CE1-CH2 3.87Å; F259-W352 AromaticContact CE1-CZ3 3.92Å; F259-W352 HydrophobicContact CE1-CZ3 3.92Å; L260-W352 HydrophobicContact CD2-CD2 3.24Å; L260-W352 HydrophobicContact CD2-CE3 3.5Å; L260-W352 HydrophobicContact CD2-CG 3.84Å; L260-W352 HydrophobicContact CD2-CH2 3.71Å; L260-W352 HydrophobicContact CD2-CZ2 3.45Å; L260-W352 VanDerWaalsContact CD2-CZ2 3.45Å; L260-W352 HydrophobicContact CD2-CZ3 3.73Å; F329-W352 HydrophobicContact CE1-CH2 4.4Å; F329-W352 AromaticContact CE1-CZ3 3.94Å; F329-W352 HydrophobicContact CE1-CZ3 3.94Å; F329-W352 HydrophobicContact CZ-CH2 4.29Å; F329-W352 HydrophobicContact CZ-CZ3 4.13Å; D348-W352 PolarHBondContact O-N 2.93Å; Q349-W352 PolarHBondContact O-N 3.41Å; W352-E354 VanDerWaalsContact C-N 3.29Å; W352-E354 PolarHBondContact O-N 3.2Å; W352-E355 PolarHBondContact O-N 2.88Å; W352-T356 VanDerWaalsContact CE2-OG1 3.22Å; W352-T356 HydrophobicContact CH2-CG2 4.16Å; W352-T356 HydrophobicContact CZ2-CG2 4.16Å; W352-T356 WeakPolarHBondContact CZ2-OG1 3.32Å; W352-T356 VanDerWaalsContact O-CB 3.3Å; W352-T356 WeakPolarHBondContact O-CB 3.44Å; W352-T356 PolarHBondContact O-N 3.45Å; W352-T356 PolarHBondContact O-OG1 3.13Å
353I94.4Very high91.5Very high0 Ų061.2 Ų61.20%032%0.319CS..Hα-helixtrans-61-40.3175.6-69.9168.2000110.5W256 F329 L332 K333 L345 Q349 S350 A351 T357W256-I353 HydrophobicContact CH2-CD1 4Å; W256-I353 HydrophobicContact CH2-CG1 4.02Å; F329-I353 HydrophobicContact CB-CG2 3.72Å; F329-I353 HydrophobicContact CD1-CG1 4.29Å; F329-I353 HydrophobicContact CD1-CG2 3.97Å; F329-I353 HydrophobicContact CD2-CG2 4.3Å; F329-I353 HydrophobicContact CG-CG2 3.75Å; L332-I353 HydrophobicContact CB-CD1 4.34Å; L332-I353 HydrophobicContact CD1-CD1 4.28Å; K333-I353 HydrophobicContact CD-CG2 4.08Å; K333-I353 HydrophobicContact CG-CG2 4.36Å; L345-I353 HydrophobicContact CD1-CD1 3.68Å; Q349-I353 VanDerWaalsContact O-CG1 3.28Å; Q349-I353 WeakPolarHBondContact O-CG1 3.5Å; Q349-I353 PolarHBondContact O-N 3.49Å; S350-I353 PolarHBondContact O-N 2.94Å; A351-I353 VanDerWaalsContact C-N 3.34Å; A351-I353 PolarHBondContact O-N 3.13Å; I353-T357 VanDerWaalsContact O-CB 3.23Å; I353-T357 WeakPolarHBondContact O-CB 3.32Å; I353-T357 PolarHBondContact O-N 3.42Å; I353-T357 PolarHBondContact O-OG1 3.16Å
354E93.8Very high92Very high95 Ų9560.1 Ų60.144%0.44431%0.312SS..Hα-helixtrans-66-44.9178.6-74.3179.6-173.100113.4K333 S350 A351 W352 T357 K358K333-E354 IonicContact NZ-OE1 3.84Å; K333-E354 PolarHBondContact NZ-OE1 3.01Å; S350-E354 WeakPolarHBondContact O-CG 3.46Å; S350-E354 PolarHBondContact O-N 3.49Å; S350-E354 VanDerWaalsContact O-N 3.09Å; A351-E354 WeakPolarHBondContact O-CB 3.34Å; A351-E354 PolarHBondContact O-N 3.34Å; A351-E354 VanDerWaalsContact O-N 3.17Å; W352-E354 VanDerWaalsContact C-N 3.29Å; W352-E354 PolarHBondContact O-N 3.2Å; E354-T357 PolarHBondContact O-N 2.85Å; E354-K358 WeakPolarHBondContact O-CG 3.45Å; E354-K358 PolarHBondContact O-N 3Å; E354-K358 VanDerWaalsContact O-N 3.14Å
355E95.7Very high92.5Very high142 Ų14260.7 Ų60.766%0.66430%0.303SS*.Hα-helixtrans-62.4-46.6176.1-174.5173.7-173.100110.8A351 W352 T357 K358 L359A351-E355 PolarHBondContact O-N 3.35Å; W352-E355 PolarHBondContact O-N 2.88Å; E355-T357 VanDerWaalsContact C-N 3.35Å; E355-T357 PolarHBondContact O-N 3Å; E355-K358 WeakPolarHBondContact O-CB 3.23Å; E355-K358 PolarHBondContact O-N 2.88Å; E355-L359 PolarHBondContact O-N 3.18Å
356T94.2Very high92.7Very high6 Ų662.9 Ų62.94%0.03731%0.313CS..Hα-helixtrans-67.2-36179.9-50.70000111.8L267 F329 W352 K358 L359 V360L267-T356 HydrophobicContact CD1-CG2 3.45Å; L267-T356 VanDerWaalsContact CD1-CG2 3.45Å; F329-T356 HydrophobicContact CE2-CG2 3.82Å; F329-T356 HydrophobicContact CZ-CG2 3.68Å; W352-T356 VanDerWaalsContact CE2-OG1 3.22Å; W352-T356 HydrophobicContact CH2-CG2 4.16Å; W352-T356 HydrophobicContact CZ2-CG2 4.16Å; W352-T356 WeakPolarHBondContact CZ2-OG1 3.32Å; W352-T356 VanDerWaalsContact O-CB 3.3Å; W352-T356 WeakPolarHBondContact O-CB 3.44Å; W352-T356 PolarHBondContact O-N 3.45Å; W352-T356 PolarHBondContact O-OG1 3.13Å; T356-K358 PolarHBondContact O-N 3.49Å; T356-L359 WeakPolarHBondContact O-CB 3.35Å; T356-L359 PolarHBondContact O-N 3.34Å; T356-V360 HydrophobicContact CG2-CG2 4.43Å; T356-V360 VanDerWaalsContact O-CG2 3.29Å; T356-V360 WeakPolarHBondContact O-CG2 3.29Å; T356-V360 PolarHBondContact O-N 3.47Å
357T95.6Very high92.5Very high29 Ų2958.5 Ų58.518%0.17829%0.289CS..Hα-helixtrans-60.7-44.6174.1-61.90000111L326 F329 I353 E354 E355 L359 V360 Y361L326-T357 HydrophobicContact CD2-CG2 3.99Å; F329-T357 VanDerWaalsContact CD2-OG1 3.28Å; F329-T357 WeakPolarHBondContact CD2-OG1 3.44Å; I353-T357 VanDerWaalsContact O-CB 3.23Å; I353-T357 WeakPolarHBondContact O-CB 3.32Å; I353-T357 PolarHBondContact O-N 3.42Å; I353-T357 PolarHBondContact O-OG1 3.16Å; E354-T357 PolarHBondContact O-N 2.85Å; E355-T357 VanDerWaalsContact C-N 3.35Å; E355-T357 PolarHBondContact O-N 3Å; T357-L359 VanDerWaalsContact C-N 3.32Å; T357-L359 PolarHBondContact O-N 3.29Å; T357-V360 PolarHBondContact O-N 2.9Å; T357-Y361 HydrophobicContact CG2-CD2 3.8Å; T357-Y361 HydrophobicContact CG2-CE2 3.7Å; T357-Y361 VanDerWaalsContact O-CD2 3.3Å; T357-Y361 WeakPolarHBondContact O-CD2 3.44Å; T357-Y361 PolarHBondContact O-N 3.24Å
358K95.4Very high92Very high151 Ų15152.8 Ų52.866%0.65726%0.26SS*.Hα-helixtrans-61.1-42.3175.5-69.3169.3-175170.40111.4E354 E355 T356 Y361 Q362E354-K358 WeakPolarHBondContact O-CG 3.45Å; E354-K358 PolarHBondContact O-N 3Å; E354-K358 VanDerWaalsContact O-N 3.14Å; E355-K358 WeakPolarHBondContact O-CB 3.23Å; E355-K358 PolarHBondContact O-N 2.88Å; T356-K358 PolarHBondContact O-N 3.49Å; K358-Y361 PolarHBondContact O-N 3.11Å; K358-Q362 PolarHBondContact O-N 3.16Å
359L94.4Very high91.7Very high43 Ų4348.7 Ų48.723%0.22524%0.241CC..Hα-helixtrans-62.2-44.3175.8179.763.7000111.8L267 K271 E355 T356 T357 Q362 L363L267-L359 HydrophobicContact CB-CD2 4.33Å; L267-L359 HydrophobicContact CD1-CD2 4.36Å; K271-L359 HydrophobicContact CD-CD1 4.41Å; E355-L359 PolarHBondContact O-N 3.18Å; T356-L359 WeakPolarHBondContact O-CB 3.35Å; T356-L359 PolarHBondContact O-N 3.34Å; T357-L359 VanDerWaalsContact C-N 3.32Å; T357-L359 PolarHBondContact O-N 3.29Å; L359-Q362 WeakPolarHBondContact O-CB 3.42Å; L359-Q362 PolarHBondContact O-N 3.24Å; L359-L363 HydrophobicContact CD1-CG 4.49Å; L359-L363 HydrophobicContact CG-CD1 4.32Å; L359-L363 WeakPolarHBondContact O-CG 3.49Å; L359-L363 PolarHBondContact O-N 2.73Å
360V95.2Very high91.4Very high0 Ų053.2 Ų53.20%026%0.262CS..Hα-helixtrans-63.2-43.2178.9169.90000111.4L267 L322 L326 F329 T356 T357 Q362 L363 L364L267-V360 HydrophobicContact CD1-CG2 4.46Å; L267-V360 HydrophobicContact CD2-CG2 4.17Å; L322-V360 HydrophobicContact CB-CG1 3.98Å; L322-V360 HydrophobicContact CD2-CB 4.48Å; L322-V360 HydrophobicContact CD2-CG1 3.99Å; L322-V360 HydrophobicContact CD2-CG2 4.24Å; L322-V360 WeakPolarHBondContact O-CG1 3.08Å; L326-V360 HydrophobicContact CD1-CG1 4.23Å; L326-V360 HydrophobicContact CD2-CB 4.19Å; L326-V360 HydrophobicContact CD2-CG1 3.69Å; L326-V360 HydrophobicContact CG-CG1 3.69Å; F329-V360 HydrophobicContact CE2-CG2 4.38Å; T356-V360 HydrophobicContact CG2-CG2 4.43Å; T356-V360 VanDerWaalsContact O-CG2 3.29Å; T356-V360 WeakPolarHBondContact O-CG2 3.29Å; T356-V360 PolarHBondContact O-N 3.47Å; T357-V360 PolarHBondContact O-N 2.9Å; V360-Q362 VanDerWaalsContact C-N 3.33Å; V360-Q362 PolarHBondContact O-N 2.92Å; V360-L363 PolarHBondContact O-N 3.37Å; V360-L364 HydrophobicContact CG1-CD1 4.31Å; V360-L364 WeakPolarHBondContact O-CG 3.46Å; V360-L364 PolarHBondContact O-N 3.04Å
361Y94.6Very high91.1Very high38 Ų3852 Ų5215%0.14925%0.254CS..Hα-helixtrans-62.5-39.5173.1-84.6-67.5000112.5L326 T357 K358 L364 R365 A375 E379 L382L326-Y361 HydrophobicContact CD1-CD1 4.49Å; L326-Y361 HydrophobicContact CD1-CE1 4.03Å; L326-Y361 HydrophobicContact CD1-CE2 4.46Å; L326-Y361 HydrophobicContact CD2-CD2 4.13Å; L326-Y361 HydrophobicContact CD2-CE2 3.81Å; T357-Y361 HydrophobicContact CG2-CD2 3.8Å; T357-Y361 HydrophobicContact CG2-CE2 3.7Å; T357-Y361 VanDerWaalsContact O-CD2 3.3Å; T357-Y361 WeakPolarHBondContact O-CD2 3.44Å; T357-Y361 PolarHBondContact O-N 3.24Å; K358-Y361 PolarHBondContact O-N 3.11Å; Y361-L364 PolarHBondContact O-N 3.5Å; Y361-R365 WeakPolarHBondContact O-CG 3.32Å; Y361-R365 PolarHBondContact O-N 3.08Å; Y361-A375 HydrophobicContact CD1-CB 4.41Å; Y361-E379 HydrophobicContact CE1-CB 4.27Å; Y361-L382 WeakPolarHBondContact OH-CD1 3.29Å
362Q93.4Very high90.9Very high90 Ų9054.1 Ų54.142%0.42126%0.255SS..Hα-helixtrans-59.9-47.7173.7-177-176.6-9.700111.1K358 L359 V360 L364 R365 E366K358-Q362 PolarHBondContact O-N 3.16Å; L359-Q362 WeakPolarHBondContact O-CB 3.42Å; L359-Q362 PolarHBondContact O-N 3.24Å; V360-Q362 VanDerWaalsContact C-N 3.33Å; V360-Q362 PolarHBondContact O-N 2.92Å; Q362-L364 VanDerWaalsContact C-N 3.34Å; Q362-L364 PolarHBondContact O-N 2.67Å; Q362-R365 PolarHBondContact O-N 3.32Å; Q362-E366 WeakPolarHBondContact CG-OE1 3.48Å; Q362-E366 PolarHBondContact NE2-OE1 3.44Å; Q362-E366 WeakPolarHBondContact O-CG 3.47Å; Q362-E366 PolarHBondContact O-N 3.16Å
363L90.9Very high90.8Very high9 Ų958.2 Ų58.25%0.04728%0.276CS..Hα-helixtrans-64.4-36.4178.7-67.8174.7000112.6L267 F270 K271 L322 L359 V360 E366 T367L267-L363 HydrophobicContact CD2-CD1 4.04Å; F270-L363 HydrophobicContact CB-CD1 4.15Å; K271-L363 HydrophobicContact CB-CD2 4.17Å; L322-L363 HydrophobicContact CD1-CB 3.95Å; L322-L363 HydrophobicContact CD2-CB 4.28Å; L322-L363 HydrophobicContact CD2-CD1 4.15Å; L359-L363 HydrophobicContact CD1-CG 4.49Å; L359-L363 HydrophobicContact CG-CD1 4.32Å; L359-L363 WeakPolarHBondContact O-CG 3.49Å; L359-L363 PolarHBondContact O-N 2.73Å; V360-L363 PolarHBondContact O-N 3.37Å; L363-E366 PolarHBondContact O-N 3.35Å; L363-T367 PolarHBondContact O-N 3.35Å; L363-T367 VanDerWaalsContact O-N 3.11Å; L363-T367 PolarHBondContact O-OG1 3.33Å
364L91.6Very high90.7Very high0 Ų060.1 Ų60.10%028%0.284CS..Hα-helixtrans-63.9-43.5174.2-79.2173.4000111.9R319 L322 L326 V360 Y361 Q362 E366 T367 G371 F374 A375R319-L364 HydrophobicContact CG-CD2 4.2Å; L322-L364 HydrophobicContact CB-CD1 4.4Å; L322-L364 HydrophobicContact CB-CD2 3.67Å; L322-L364 HydrophobicContact CB-CG 3.9Å; L322-L364 HydrophobicContact CD1-CD2 3.76Å; L322-L364 HydrophobicContact CD1-CG 3.94Å; L322-L364 HydrophobicContact CG-CD2 4.38Å; L326-L364 HydrophobicContact CD1-CD1 3.57Å; V360-L364 HydrophobicContact CG1-CD1 4.31Å; V360-L364 WeakPolarHBondContact O-CG 3.46Å; V360-L364 PolarHBondContact O-N 3.04Å; Y361-L364 PolarHBondContact O-N 3.5Å; Q362-L364 VanDerWaalsContact C-N 3.34Å; Q362-L364 PolarHBondContact O-N 2.67Å; L364-E366 VanDerWaalsContact C-N 3.3Å; L364-E366 PolarHBondContact O-N 3.24Å; L364-T367 WeakPolarHBondContact O-CB 3.26Å; L364-T367 PolarHBondContact O-N 3.45Å; L364-T367 VanDerWaalsContact O-N 3.11Å; L364-G371 WeakPolarHBondContact O-CA 3.49Å; L364-F374 HydrophobicContact CD2-CD1 4.25Å; L364-F374 HydrophobicContact CD2-CE1 4.01Å; L364-A375 HydrophobicContact CB-CB 4.47Å
365R91.7Very high90.6Very high112 Ų11255.6 Ų55.642%0.42326%0.263SS..Hα-helixtrans-62.4-38.3175.2-71.4175.3171141.111.6112.1Y361 Q362 T367 E372 A375Y361-R365 WeakPolarHBondContact O-CG 3.32Å; Y361-R365 PolarHBondContact O-N 3.08Å; Q362-R365 PolarHBondContact O-N 3.32Å; R365-T367 PolarHBondContact O-N 3.19Å; R365-E372 WeakPolarHBondContact CD-OE2 3.42Å; R365-E372 WeakPolarHBondContact CG-OE2 3.44Å; R365-E372 IonicContact CZ-OE1 3.32Å; R365-E372 IonicContact NE-OE1 3.86Å; R365-E372 PolarHBondContact NE-OE1 3.38Å; R365-E372 IonicContact NE-OE2 2.96Å; R365-E372 PolarHBondContact NE-OE2 3.02Å; R365-E372 IonicContact NH2-OE1 2.81Å; R365-A375 HydrophobicContact CG-CB 3.73Å
366E88.6Confident90.5Very high72 Ų7252.4 Ų52.434%0.33625%0.253SS..THydrogen-bonded Turntrans-73.6-9.9176.1-69.5-177-155.400113.4K274 Q362 L363 L364 P368K274-E366 IonicContact NZ-OE1 3.52Å; K274-E366 IonicContact NZ-OE2 3.91Å; K274-E366 PolarHBondContact NZ-OE2 3.05Å; Q362-E366 WeakPolarHBondContact CG-OE1 3.48Å; Q362-E366 PolarHBondContact NE2-OE1 3.44Å; Q362-E366 WeakPolarHBondContact O-CG 3.47Å; Q362-E366 PolarHBondContact O-N 3.16Å; L363-E366 PolarHBondContact O-N 3.35Å; L364-E366 VanDerWaalsContact C-N 3.3Å; L364-E366 PolarHBondContact O-N 3.24Å; E366-P368 VanDerWaalsContact O-CD 3.32Å; E366-P368 WeakPolarHBondContact O-CD 3.43Å
367T85.3Confident90.5Very high7 Ų757 Ų574%0.04328%0.276CS..SBendtrans-92.6110.8-177.6-59.80000111.8L275 R319 L363 L364 R365 G371L275-T367 HydrophobicContact CD1-CG2 4.34Å; R319-T367 HydrophobicContact CG-CG2 4.12Å; R319-T367 PolarHBondContact NH2-O 3.49Å; L363-T367 PolarHBondContact O-N 3.35Å; L363-T367 VanDerWaalsContact O-N 3.11Å; L363-T367 PolarHBondContact O-OG1 3.33Å; L364-T367 WeakPolarHBondContact O-CB 3.26Å; L364-T367 PolarHBondContact O-N 3.45Å; L364-T367 VanDerWaalsContact O-N 3.11Å; R365-T367 PolarHBondContact O-N 3.19Å; T367-G371 WeakPolarHBondContact O-CA 3.14Å
368P79.6Confident90.5Very high23 Ų2355.9 Ų55.915%0.14927%0.269CS..SBendtrans-67.6160.5174.7-15.631.4000112D277 S315 R319 E366D277-P368 WeakPolarHBondContact OD1-CB 3.45Å; S315-P368 WeakPolarHBondContact CB-O 3.43Å; R319-P368 VanDerWaalsContact NH2-C 3.3Å; R319-P368 PolarHBondContact NH2-O 3.36Å; E366-P368 VanDerWaalsContact O-CD 3.32Å; E366-P368 WeakPolarHBondContact O-CD 3.43Å
369P83.5Confident90.4Very high50 Ų5052.8 Ų52.833%0.32526%0.257SS..SBendcis-85.9142.4-7.233-34.2000113R319 G371R319-P369 PolarHBondContact NH2-O 3.38Å; P369-G371 PolarHBondContact O-N 3.47Å
370E82.3Confident90.4Very high124 Ų12456.6 Ų56.658%0.57927%0.273SS*.SBendtrans57.344.7176.3-58177.3174.100114.1E372 Q373 F374E370-E372 VanDerWaalsContact C-N 3.28Å; E370-E372 PolarHBondContact O-N 2.74Å; E370-Q373 HydrophobicContact CB-CB 4.41Å; E370-Q373 PolarHBondContact O-N 2.92Å; E370-Q373 PolarHBondContact OE2-OE1 3.36Å; E370-F374 PolarHBondContact O-N 3.06Å
371G85.2Confident90.5Very high6 Ų660 Ų606%0.06229%0.291CS..Hα-helixtrans-54.8-37.8-176.600000114.5L364 T367 P369 F374 A375L364-G371 WeakPolarHBondContact O-CA 3.49Å; T367-G371 WeakPolarHBondContact O-CA 3.14Å; P369-G371 PolarHBondContact O-N 3.47Å; G371-F374 PolarHBondContact O-N 3.09Å; G371-A375 WeakPolarHBondContact O-CB 3.39Å; G371-A375 PolarHBondContact O-N 3.43Å
372E89.1Confident90.4Very high100 Ų10059 Ų5947%0.46729%0.287SS..Hα-helixtrans-64.6-48.2178.4-166.364.4-141.100112.2R365 E370 F374 A375 T376R365-E372 WeakPolarHBondContact CD-OE2 3.42Å; R365-E372 WeakPolarHBondContact CG-OE2 3.44Å; R365-E372 IonicContact CZ-OE1 3.32Å; R365-E372 IonicContact NE-OE1 3.86Å; R365-E372 PolarHBondContact NE-OE1 3.38Å; R365-E372 IonicContact NE-OE2 2.96Å; R365-E372 PolarHBondContact NE-OE2 3.02Å; R365-E372 IonicContact NH2-OE1 2.81Å; E370-E372 VanDerWaalsContact C-N 3.28Å; E370-E372 PolarHBondContact O-N 2.74Å; E372-F374 VanDerWaalsContact C-N 3.3Å; E372-F374 PolarHBondContact O-N 3.43Å; E372-A375 PolarHBondContact O-N 3.11Å; E372-T376 PolarHBondContact O-N 3.46Å; E372-T376 PolarHBondContact O-OG1 3.23Å; E372-T376 VanDerWaalsContact O-OG1 3.09Å
373Q91.2Very high90.4Very high125 Ų12558.3 Ų58.358%0.58429%0.287SS*.Hα-helixtrans-63.7-40.9179-62-176.422.300111E370 T376 M377E370-Q373 HydrophobicContact CB-CB 4.41Å; E370-Q373 PolarHBondContact O-N 2.92Å; E370-Q373 PolarHBondContact OE2-OE1 3.36Å; Q373-T376 PolarHBondContact O-N 3.03Å; Q373-M377 WeakPolarHBondContact O-CB 3.44Å; Q373-M377 PolarHBondContact O-N 3.09Å
374F92.6Very high90.5Very high41 Ų4160.9 Ų60.918%0.1830%0.303CS..Hα-helixtrans-60.7-46.9175.4-172.3-97.5000111.3R319 L323 L364 E370 G371 E372 T376 M377 V378R319-F374 HydrophobicContact CB-CE1 4.17Å; R319-F374 HydrophobicContact CB-CZ 4.21Å; R319-F374 HydrophobicContact CG-CD1 4.45Å; R319-F374 HydrophobicContact CG-CE1 3.96Å; R319-F374 HydrophobicContact CG-CZ 4.28Å; L323-F374 HydrophobicContact CD1-CE1 4.36Å; L323-F374 HydrophobicContact CD1-CZ 3.91Å; L323-F374 HydrophobicContact CD2-CE1 4.42Å; L323-F374 HydrophobicContact CG-CE1 4.41Å; L323-F374 HydrophobicContact CG-CZ 4.44Å; L364-F374 HydrophobicContact CD2-CD1 4.25Å; L364-F374 HydrophobicContact CD2-CE1 4.01Å; E370-F374 PolarHBondContact O-N 3.06Å; G371-F374 PolarHBondContact O-N 3.09Å; E372-F374 VanDerWaalsContact C-N 3.3Å; E372-F374 PolarHBondContact O-N 3.43Å; F374-T376 PolarHBondContact O-N 3.11Å; F374-M377 HydrophobicContact CD2-CE 3.99Å; F374-M377 HydrophobicContact CE2-CE 4.24Å; F374-M377 PolarHBondContact O-N 3.11Å; F374-V378 HydrophobicContact CD1-CG2 4.01Å; F374-V378 HydrophobicContact CE1-CG2 3.75Å; F374-V378 HydrophobicContact CZ-CG2 4.11Å; F374-V378 VanDerWaalsContact O-CG2 3.23Å; F374-V378 WeakPolarHBondContact O-CG2 3.38Å; F374-V378 PolarHBondContact O-N 3.4Å
375A92.5Very high90.5Very high0 Ų064.6 Ų64.60%032%0.32CS..Hα-helixtrans-60.8-43.8178.200000112.4Y361 L364 R365 G371 E372 M377 V378 E379Y361-A375 HydrophobicContact CD1-CB 4.41Å; L364-A375 HydrophobicContact CB-CB 4.47Å; R365-A375 HydrophobicContact CG-CB 3.73Å; G371-A375 WeakPolarHBondContact O-CB 3.39Å; G371-A375 PolarHBondContact O-N 3.43Å; E372-A375 PolarHBondContact O-N 3.11Å; A375-M377 PolarHBondContact O-N 3.05Å; A375-V378 PolarHBondContact O-N 3.04Å; A375-E379 PolarHBondContact O-N 2.91Å
376T94.1Very high90.4Very high75 Ų7564.7 Ų64.746%0.4633%0.325SS..Hα-helixtrans-63.4-40.2175.7-51.70000112.2E372 Q373 F374 E379 H380E372-T376 PolarHBondContact O-N 3.46Å; E372-T376 PolarHBondContact O-OG1 3.23Å; E372-T376 VanDerWaalsContact O-OG1 3.09Å; Q373-T376 PolarHBondContact O-N 3.03Å; F374-T376 PolarHBondContact O-N 3.11Å; T376-E379 PolarHBondContact O-N 3.04Å; T376-H380 PolarHBondContact O-N 2.89Å
377M94.6Very high90.5Very high102 Ų10266.8 Ų66.850%0.50234%0.339SS..Hα-helixtrans-64.6-41.8176.6-176.6176.265.900111.5Q373 F374 A375 H380 I381Q373-M377 WeakPolarHBondContact O-CB 3.44Å; Q373-M377 PolarHBondContact O-N 3.09Å; F374-M377 HydrophobicContact CD2-CE 3.99Å; F374-M377 HydrophobicContact CE2-CE 4.24Å; F374-M377 PolarHBondContact O-N 3.11Å; A375-M377 PolarHBondContact O-N 3.05Å; M377-H380 PolarHBondContact O-N 3.46Å; M377-I381 HydrophobicContact CG-CD1 3.98Å; M377-I381 VanDerWaalsContact O-CG1 3.29Å; M377-I381 WeakPolarHBondContact O-CG1 3.47Å; M377-I381 PolarHBondContact O-N 3.45Å
378V94.9Very high90.6Very high5 Ų573.1 Ų73.13%0.0336%0.362CS..Hα-helixtrans-62.3-45.4176.1171.30000110.8L323 L326 F374 A375 H380 I381 L382L323-V378 HydrophobicContact CD2-CB 4.27Å; L323-V378 HydrophobicContact CD2-CG1 3.63Å; L323-V378 HydrophobicContact CD2-CG2 3.55Å; L326-V378 HydrophobicContact CD1-CG1 3.65Å; F374-V378 HydrophobicContact CD1-CG2 4.01Å; F374-V378 HydrophobicContact CE1-CG2 3.75Å; F374-V378 HydrophobicContact CZ-CG2 4.11Å; F374-V378 VanDerWaalsContact O-CG2 3.23Å; F374-V378 WeakPolarHBondContact O-CG2 3.38Å; F374-V378 PolarHBondContact O-N 3.4Å; A375-V378 PolarHBondContact O-N 3.04Å; V378-H380 VanDerWaalsContact C-N 3.31Å; V378-H380 PolarHBondContact O-N 3.46Å; V378-I381 PolarHBondContact O-N 3.25Å; V378-I381 VanDerWaalsContact O-N 3.15Å; V378-L382 HydrophobicContact CG1-CD1 3.84Å; V378-L382 HydrophobicContact CG1-CG 4.25Å; V378-L382 VanDerWaalsContact O-CG 3.3Å; V378-L382 WeakPolarHBondContact O-CG 3.48Å; V378-L382 PolarHBondContact O-N 3.12Å
379E93.8Very high91.1Very high87 Ų8774.1 Ų74.141%0.40737%0.366SS..Hα-helixtrans-58.1-43.6175.4-173.5174.9-165.200111.6Y361 A375 T376 L382 N383Y361-E379 HydrophobicContact CE1-CB 4.27Å; A375-E379 PolarHBondContact O-N 2.91Å; T376-E379 PolarHBondContact O-N 3.04Å; E379-L382 PolarHBondContact O-N 3.09Å; E379-N383 WeakPolarHBondContact O-CB 2.94Å; E379-N383 PolarHBondContact O-N 2.91Å; E379-N383 PolarHBondContact O-ND2 2.7Å; E379-N383 VanDerWaalsContact O-ND2 3.15Å
380H94.9Very high91.3Very high123 Ų12374.5 Ų74.557%0.56937%0.37SS*.Hα-helixtrans-61.6-44.2174.4-176.871.1000112.6T376 M377 V378 N383 T384T376-H380 PolarHBondContact O-N 2.89Å; M377-H380 PolarHBondContact O-N 3.46Å; V378-H380 VanDerWaalsContact C-N 3.31Å; V378-H380 PolarHBondContact O-N 3.46Å; H380-N383 WeakPolarHBondContact O-CB 3.34Å; H380-N383 PolarHBondContact O-N 3.42Å; H380-T384 WeakPolarHBondContact O-CG2 3.17Å; H380-T384 PolarHBondContact O-N 3Å
381I95.8Very high91.6Very high72 Ų7269.3 Ų69.337%0.36935%0.345SS..Hα-helixtrans-62.2-48.6178.5-70165.3000110.5M377 V378 N383 T384 E385M377-I381 HydrophobicContact CG-CD1 3.98Å; M377-I381 VanDerWaalsContact O-CG1 3.29Å; M377-I381 WeakPolarHBondContact O-CG1 3.47Å; M377-I381 PolarHBondContact O-N 3.45Å; V378-I381 PolarHBondContact O-N 3.25Å; V378-I381 VanDerWaalsContact O-N 3.15Å; I381-N383 VanDerWaalsContact C-N 3.28Å; I381-N383 PolarHBondContact O-N 2.92Å; I381-T384 WeakPolarHBondContact CA-OG1 3.29Å; I381-T384 CarbonylContact O-C 3.5Å; I381-T384 WeakPolarHBondContact O-CA 3.41Å; I381-T384 PolarHBondContact O-N 3.25Å; I381-T384 PolarHBondContact O-OG1 3.43Å; I381-E385 HydrophobicContact CG2-CG 4.5Å; I381-E385 PolarHBondContact O-N 2.96Å
382L93.3Very high91.7Very high15 Ų1570.9 Ų70.98%0.07935%0.35CS..Hα-helixtrans-61.4-37.8179.3-63.9172.9000111.3L326 I327 Q330 Y361 V378 E379 T384 E385 E386L326-L382 HydrophobicContact CB-CD1 3.93Å; L326-L382 HydrophobicContact CD1-CD1 4.18Å; I327-L382 HydrophobicContact CG1-CD2 4.33Å; Q330-L382 PolarHBondContact NE2-O 3.29Å; Q330-L382 VanDerWaalsContact OE1-CB 3.27Å; Y361-L382 WeakPolarHBondContact OH-CD1 3.29Å; V378-L382 HydrophobicContact CG1-CD1 3.84Å; V378-L382 HydrophobicContact CG1-CG 4.25Å; V378-L382 VanDerWaalsContact O-CG 3.3Å; V378-L382 WeakPolarHBondContact O-CG 3.48Å; V378-L382 PolarHBondContact O-N 3.12Å; E379-L382 PolarHBondContact O-N 3.09Å; L382-T384 PolarHBondContact O-N 3.39Å; L382-E385 WeakPolarHBondContact O-CB 3.48Å; L382-E385 PolarHBondContact O-N 3Å; L382-E386 PolarHBondContact O-N 3.33Å; L382-E386 VanDerWaalsContact O-N 3.14Å
383N93.1Very high91.5Very high77 Ų7768 Ų6841%0.41234%0.338SS..Hα-helixtrans-62.5-39.1171.7-69.7-26.1000112.4E379 H380 I381 E385 E386E379-N383 WeakPolarHBondContact O-CB 2.94Å; E379-N383 PolarHBondContact O-N 2.91Å; E379-N383 PolarHBondContact O-ND2 2.7Å; E379-N383 VanDerWaalsContact O-ND2 3.15Å; H380-N383 WeakPolarHBondContact O-CB 3.34Å; H380-N383 PolarHBondContact O-N 3.42Å; I381-N383 VanDerWaalsContact C-N 3.28Å; I381-N383 PolarHBondContact O-N 2.92Å; N383-E385 VanDerWaalsContact C-N 3.33Å; N383-E386 PolarHBondContact O-N 2.97Å
384T93.1Very high91.2Very high63 Ų6368.5 Ų68.539%0.38734%0.34SS..Hα-helixtrans-69.4-29.8173.962.30000113H380 I381 L382 E386 N387 W388H380-T384 WeakPolarHBondContact O-CG2 3.17Å; H380-T384 PolarHBondContact O-N 3Å; I381-T384 WeakPolarHBondContact CA-OG1 3.29Å; I381-T384 CarbonylContact O-C 3.5Å; I381-T384 WeakPolarHBondContact O-CA 3.41Å; I381-T384 PolarHBondContact O-N 3.25Å; I381-T384 PolarHBondContact O-OG1 3.43Å; L382-T384 PolarHBondContact O-N 3.39Å; T384-E386 VanDerWaalsContact C-N 3.32Å; T384-N387 WeakPolarHBondContact O-CB 3.45Å; T384-N387 PolarHBondContact O-N 3.15Å; T384-W388 PolarHBondContact O-N 3.5Å; T384-W388 VanDerWaalsContact O-N 3.11Å
385E91.4Very high90.7Very high78 Ų7868.7 Ų68.736%0.36435%0.354SS..Hα-helixtrans-66.5-32.8173.4-71.1-173.1179.900112.2I381 L382 N383 N387 W388 N389I381-E385 HydrophobicContact CG2-CG 4.5Å; I381-E385 PolarHBondContact O-N 2.96Å; L382-E385 WeakPolarHBondContact O-CB 3.48Å; L382-E385 PolarHBondContact O-N 3Å; N383-E385 VanDerWaalsContact C-N 3.33Å; E385-N387 VanDerWaalsContact C-N 3.32Å; E385-N387 PolarHBondContact O-N 3.35Å; E385-W388 WeakPolarHBondContact O-CB 3.33Å; E385-W388 PolarHBondContact O-N 3.33Å; E385-N389 WeakPolarHBondContact O-CB 3.23Å; E385-N389 PolarHBondContact O-N 2.88Å
386E89.8Confident90.2Very high113 Ų11369 Ų6953%0.52836%0.357SS..Hα-helixtrans-60.8-43.2172.6-63.2-170162.200111.4L382 N383 T384 W388 N389 S390L382-E386 PolarHBondContact O-N 3.33Å; L382-E386 VanDerWaalsContact O-N 3.14Å; N383-E386 PolarHBondContact O-N 2.97Å; T384-E386 VanDerWaalsContact C-N 3.32Å; E386-W388 VanDerWaalsContact C-N 3.32Å; E386-W388 PolarHBondContact O-N 3.03Å; E386-N389 PolarHBondContact O-N 3.25Å; E386-S390 PolarHBondContact O-N 2.66Å
387N90.3Very high89.6Confident117 Ų11768.3 Ų68.363%0.62635%0.353SS*.Hα-helixtrans-61.3-42.7175-61.9-37.4000111.2T384 E385 S390 W391T384-N387 WeakPolarHBondContact O-CB 3.45Å; T384-N387 PolarHBondContact O-N 3.15Å; E385-N387 VanDerWaalsContact C-N 3.32Å; E385-N387 PolarHBondContact O-N 3.35Å; N387-S390 PolarHBondContact O-N 3.01Å; N387-W391 PolarHBondContact O-N 2.89Å
388W88.8Confident88.8Confident140 Ų14066.4 Ų66.453%0.5335%0.35SS..Hα-helixtrans-63.8-40.7176.8-172.6-100.1000112.2T384 E385 E386 W391 K392T384-W388 PolarHBondContact O-N 3.5Å; T384-W388 VanDerWaalsContact O-N 3.11Å; E385-W388 WeakPolarHBondContact O-CB 3.33Å; E385-W388 PolarHBondContact O-N 3.33Å; E386-W388 VanDerWaalsContact C-N 3.32Å; E386-W388 PolarHBondContact O-N 3.03Å; W388-W391 HydrophobicContact CD2-CE3 4.14Å; W388-W391 HydrophobicContact CD2-CZ3 4.42Å; W388-W391 HydrophobicContact CE3-CE3 4.11Å; W388-W391 HydrophobicContact CE3-CZ3 4.39Å; W388-W391 HydrophobicContact CH2-CE3 4.11Å; W388-W391 HydrophobicContact CH2-CH2 4.16Å; W388-W391 AromaticContact CH2-CZ3 3.56Å; W388-W391 HydrophobicContact CH2-CZ3 3.56Å; W388-W391 HydrophobicContact CZ2-CE3 4.14Å; W388-W391 HydrophobicContact CZ2-CH2 4.47Å; W388-W391 AromaticContact CZ2-CZ3 3.58Å; W388-W391 HydrophobicContact CZ2-CZ3 3.58Å; W388-W391 HydrophobicContact CZ3-CE3 4.09Å; W388-W391 AromaticContact CZ3-CZ3 3.99Å; W388-W391 HydrophobicContact CZ3-CZ3 3.99Å; W388-W391 PolarHBondContact O-N 3.3Å; W388-K392 WeakPolarHBondContact O-CB 3.3Å; W388-K392 PolarHBondContact O-N 3.23Å
389N88.6Confident87.7Confident43 Ų4372.8 Ų72.823%0.2338%0.377CS..Hα-helixtrans-64.9-42.2176.2-171.423.2000111.3Q335 E385 E386 K392 N393Q335-N389 PolarHBondContact O-ND2 3.45Å; E385-N389 WeakPolarHBondContact O-CB 3.23Å; E385-N389 PolarHBondContact O-N 2.88Å; E386-N389 PolarHBondContact O-N 3.25Å; N389-K392 PolarHBondContact O-N 3.5Å; N389-N393 WeakPolarHBondContact O-CB 3.47Å; N389-N393 VanDerWaalsContact O-CG 3.26Å; N389-N393 PolarHBondContact O-N 3.34Å; N389-N393 PolarHBondContact O-ND2 3.39Å
390S88.8Confident86.6Confident58 Ų5873.1 Ų73.141%0.40639%0.385SS..Hα-helixtrans-59.3-50.7174-166.30000111.6E386 N387 K392 N393 E394E386-S390 PolarHBondContact O-N 2.66Å; N387-S390 PolarHBondContact O-N 3.01Å; S390-K392 VanDerWaalsContact C-N 3.26Å; S390-K392 PolarHBondContact O-N 3.23Å; S390-N393 WeakPolarHBondContact O-CB 3.43Å; S390-N393 PolarHBondContact O-N 2.98Å; S390-N393 VanDerWaalsContact O-N 3.1Å; S390-E394 WeakPolarHBondContact O-CG 2.93Å; S390-E394 PolarHBondContact O-N 2.85Å
391W88Confident85Confident16 Ų1676.3 Ų76.36%0.06140%0.397CS..Hα-helixtrans-57.2-39.5177174.274.9000112.6L174 N387 W388 E394 C396 P397 F399L174-W391 HydrophobicContact CD2-CH2 4.28Å; L174-W391 HydrophobicContact CD2-CZ3 4.44Å; N387-W391 PolarHBondContact O-N 2.89Å; W388-W391 HydrophobicContact CD2-CE3 4.14Å; W388-W391 HydrophobicContact CD2-CZ3 4.42Å; W388-W391 HydrophobicContact CE3-CE3 4.11Å; W388-W391 HydrophobicContact CE3-CZ3 4.39Å; W388-W391 HydrophobicContact CH2-CE3 4.11Å; W388-W391 HydrophobicContact CH2-CH2 4.16Å; W388-W391 AromaticContact CH2-CZ3 3.56Å; W388-W391 HydrophobicContact CH2-CZ3 3.56Å; W388-W391 HydrophobicContact CZ2-CE3 4.14Å; W388-W391 HydrophobicContact CZ2-CH2 4.47Å; W388-W391 AromaticContact CZ2-CZ3 3.58Å; W388-W391 HydrophobicContact CZ2-CZ3 3.58Å; W388-W391 HydrophobicContact CZ3-CE3 4.09Å; W388-W391 AromaticContact CZ3-CZ3 3.99Å; W388-W391 HydrophobicContact CZ3-CZ3 3.99Å; W388-W391 PolarHBondContact O-N 3.3Å; W391-E394 PolarHBondContact O-N 2.84Å; W391-C396 HydrophobicContact CD2-CB 4.4Å; W391-C396 VanDerWaalsContact CE2-CA 3.45Å; W391-C396 HydrophobicContact CE3-CB 4.35Å; W391-C396 HydrophobicContact CH2-CB 3.46Å; W391-C396 VanDerWaalsContact CH2-CB 3.46Å; W391-C396 VanDerWaalsContact CZ2-CA 3.48Å; W391-C396 HydrophobicContact CZ2-CB 3.49Å; W391-C396 VanDerWaalsContact CZ2-CB 3.49Å; W391-C396 HydrophobicContact CZ3-CB 3.91Å; W391-C396 WeakPolarHBondContact CZ3-SG 3.12Å; W391-C396 PolarHBondContact O-N 3.48Å; W391-P397 VanDerWaalsContact CD1-CD 3.49Å; W391-P397 VanDerWaalsContact NE1-CD 3.3Å; W391-P397 PolarHBondContact NE1-O 3.27Å; W391-F399 AromaticContact CD1-CE2 3.58Å; W391-F399 AromaticContact CD1-CZ 3.19Å; W391-F399 AromaticContact CD2-CE2 3.78Å; W391-F399 HydrophobicContact CD2-CE2 3.78Å; W391-F399 HydrophobicContact CD2-CZ 4.08Å; W391-F399 AromaticContact CE2-CD2 3.99Å; W391-F399 AromaticContact CE2-CE2 3.25Å; W391-F399 AromaticContact CE2-CZ 3.79Å; W391-F399 AromaticContact CG-CE2 3.95Å; W391-F399 HydrophobicContact CG-CE2 3.95Å; W391-F399 AromaticContact CG-CZ 3.73Å; W391-F399 HydrophobicContact CG-CZ 3.73Å; W391-F399 HydrophobicContact CZ2-CD2 4.07Å; W391-F399 AromaticContact CZ2-CE2 3.72Å; W391-F399 HydrophobicContact CZ2-CE2 3.72Å; W391-F399 AromaticContact NE1-CD2 3.85Å; W391-F399 AromaticContact NE1-CE2 3.11Å; W391-F399 AromaticContact NE1-CZ 3.21Å
392K86.4Confident83.2Confident39 Ų3981.1 Ų81.117%0.1742%0.418CS..Hα-helixtrans-68.2-40.9176.2-170.9-178.1-176.5-174.30112.5N175 S178 W388 N389 S390 E394 G395N175-K392 WeakPolarHBondContact O-CE 3.4Å; N175-K392 PolarHBondContact O-NZ 3.32Å; S178-K392 WeakPolarHBondContact OG-CE 3.25Å; S178-K392 PolarHBondContact OG-NZ 3.4Å; W388-K392 WeakPolarHBondContact O-CB 3.3Å; W388-K392 PolarHBondContact O-N 3.23Å; N389-K392 PolarHBondContact O-N 3.5Å; S390-K392 VanDerWaalsContact C-N 3.26Å; S390-K392 PolarHBondContact O-N 3.23Å; K392-E394 PolarHBondContact O-N 3.3Å; K392-G395 PolarHBondContact O-N 3.11Å
393N85.8Confident81.2Confident40 Ų4091.2 Ų91.221%0.21446%0.455CS..Hα-helixtrans-62.3-33.4175.9-74.3-27.7000112Q335 K337 N389 S390 G395Q335-N393 PolarHBondContact O-ND2 3.47Å; K337-N393 HydrophobicContact CB-CB 4.48Å; K337-N393 WeakPolarHBondContact CB-OD1 3.44Å; K337-N393 VanDerWaalsContact CD-O 3.26Å; K337-N393 WeakPolarHBondContact CD-O 3.39Å; K337-N393 PolarHBondContact N-OD1 2.91Å; K337-N393 PolarHBondContact NZ-O 2.71Å; N389-N393 WeakPolarHBondContact O-CB 3.47Å; N389-N393 VanDerWaalsContact O-CG 3.26Å; N389-N393 PolarHBondContact O-N 3.34Å; N389-N393 PolarHBondContact O-ND2 3.39Å; S390-N393 WeakPolarHBondContact O-CB 3.43Å; S390-N393 PolarHBondContact O-N 2.98Å; S390-N393 VanDerWaalsContact O-N 3.1Å; N393-G395 PolarHBondContact O-N 3.46Å
394E86.1Confident79Confident134 Ų13493.4 Ų93.463%0.62647%0.472SS*.THydrogen-bonded Turntrans-70.2-6.4172.8-69.9170.5-162.600113.7S390 W391 K392S390-E394 WeakPolarHBondContact O-CG 2.93Å; S390-E394 PolarHBondContact O-N 2.85Å; W391-E394 PolarHBondContact O-N 2.84Å; K392-E394 PolarHBondContact O-N 3.3Å
395G80Confident77Confident45 Ų4595 Ų9546%0.46449%0.485SS..THydrogen-bonded Turntrans91.623.9179.200000114K392 N393K392-G395 PolarHBondContact O-N 3.11Å; N393-G395 PolarHBondContact O-N 3.46Å
396C83.1Confident74.9Confident8 Ų898.2 Ų98.25%0.05451%0.505CS..  trans57.560.1174.9-61.20000113.5L174 W391L174-C396 HydrophobicContact CD1-CB 3.61Å; W391-C396 HydrophobicContact CD2-CB 4.4Å; W391-C396 VanDerWaalsContact CE2-CA 3.45Å; W391-C396 HydrophobicContact CE3-CB 4.35Å; W391-C396 HydrophobicContact CH2-CB 3.46Å; W391-C396 VanDerWaalsContact CH2-CB 3.46Å; W391-C396 VanDerWaalsContact CZ2-CA 3.48Å; W391-C396 HydrophobicContact CZ2-CB 3.49Å; W391-C396 VanDerWaalsContact CZ2-CB 3.49Å; W391-C396 HydrophobicContact CZ3-CB 3.91Å; W391-C396 WeakPolarHBondContact CZ3-SG 3.12Å; W391-C396 PolarHBondContact O-N 3.48Å
397P81.8Confident73Confident60 Ų6097.7 Ų97.739%0.3951%0.506SS..  trans-57.4142.6176.324.2-33.9000111.4W391 F399W391-P397 VanDerWaalsContact CD1-CD 3.49Å; W391-P397 VanDerWaalsContact NE1-CD 3.3Å; W391-P397 PolarHBondContact NE1-O 3.27Å; P397-F399 PolarHBondContact O-N 3.49Å
398S77.3Confident71.1Confident62 Ų62100.2 Ų100.243%0.43451%0.511SS..  trans-64.2122.1-179.6-1780000111V400S398-V400 WeakPolarHBondContact OG-CB 3.47Å; S398-V400 PolarHBondContact OG-N 2.99Å; S398-V400 VanDerWaalsContact OG-N 3.13Å; S398-V400 PolarHBondContact OG-O 2.9Å
399F71.8Confident69.1Low139 Ų13999.1 Ų99.161%0.6152%0.522SS*.  trans-76.9-11.6167.6-66.4-66.1000112.8W391 P397 K401W391-F399 AromaticContact CD1-CE2 3.58Å; W391-F399 AromaticContact CD1-CZ 3.19Å; W391-F399 AromaticContact CD2-CE2 3.78Å; W391-F399 HydrophobicContact CD2-CE2 3.78Å; W391-F399 HydrophobicContact CD2-CZ 4.08Å; W391-F399 AromaticContact CE2-CD2 3.99Å; W391-F399 AromaticContact CE2-CE2 3.25Å; W391-F399 AromaticContact CE2-CZ 3.79Å; W391-F399 AromaticContact CG-CE2 3.95Å; W391-F399 HydrophobicContact CG-CE2 3.95Å; W391-F399 AromaticContact CG-CZ 3.73Å; W391-F399 HydrophobicContact CG-CZ 3.73Å; W391-F399 HydrophobicContact CZ2-CD2 4.07Å; W391-F399 AromaticContact CZ2-CE2 3.72Å; W391-F399 HydrophobicContact CZ2-CE2 3.72Å; W391-F399 AromaticContact NE1-CD2 3.85Å; W391-F399 AromaticContact NE1-CE2 3.11Å; W391-F399 AromaticContact NE1-CZ 3.21Å; P397-F399 PolarHBondContact O-N 3.49Å; F399-K401 VanDerWaalsContact C-N 3.32Å; F399-K401 PolarHBondContact O-N 3.14Å
400V70.1Confident67.3Low94 Ų94104.9 Ų104.957%0.5755%0.545SS*.  trans-71.995.5173.7-1740000106.6S398 E402S398-V400 WeakPolarHBondContact OG-CB 3.47Å; S398-V400 PolarHBondContact OG-N 2.99Å; S398-V400 VanDerWaalsContact OG-N 3.13Å; S398-V400 PolarHBondContact OG-O 2.9Å; V400-E402 PolarHBondContact O-N 3.35Å
401K62.7Low65.3Low190 Ų190112.6 Ų112.683%0.82657%0.565SS**  trans-56.7109.8155.1-67.7-179.9-179.4178.90104.6F399 R403F399-K401 VanDerWaalsContact C-N 3.32Å; F399-K401 PolarHBondContact O-N 3.14Å; K401-R403 PolarHBondContact O-N 3.3Å
402E57.7Low63.3Low173 Ų173116.9 Ų116.981%0.80860%0.595SS**  trans-47.2119.2164.7-89.2178.8161.600105.1V400 T404V400-E402 PolarHBondContact O-N 3.35Å; E402-T404 PolarHBondContact O-N 3.06Å
403R50.4Low61.7Low226 Ų226121.4 Ų121.485%0.85363%0.626SS**  trans-56.3106.6156.9-71.3-178.5-178.3179.6-0.2101.3K401 S405K401-R403 PolarHBondContact O-N 3.3Å; R403-S405 VanDerWaalsContact C-N 3.33Å; R403-S405 PolarHBondContact O-N 2.94Å
404T48.3Very low60Low124 Ų124128.2 Ų128.276%0.76165%0.649SS**  trans-37.9116.415845.50000102.6E402 D406E402-T404 PolarHBondContact O-N 3.06Å; T404-D406 PolarHBondContact O-N 2.92Å
405S49.8Very low58.4Low95 Ų95131.2 Ų131.266%0.66466%0.66SS**  trans-31.2133.4178.347.40000106.9R403 D407R403-S405 VanDerWaalsContact C-N 3.33Å; R403-S405 PolarHBondContact O-N 2.94Å; S405-D407 PolarHBondContact O-N 3.17Å
406D48.5Very low56.9Low147 Ų147137.7 Ų137.779%0.78667%0.67SS**  trans-56.678.7160.1-75.4-49000105.9T404 K408T404-D406 PolarHBondContact O-N 2.92Å; D406-K408 PolarHBondContact O-N 3.41Å
407D48.7Very low55.4Low102 Ų102146.1 Ų146.155%0.54571%0.709SS.*  -49.481.2128.6-132.78.6000100.3S405 P409S405-D407 PolarHBondContact O-N 3.17Å; D407-P409 VanDerWaalsContact C-N 3.31Å; D407-P409 WeakPolarHBondContact O-CA 3.34Å
408K51.5Low53.8Low170 Ų170146.1 Ų146.174%0.73971%0.714SS**  trans-32.4113.7153.4-74.5177177.5176.70101.4D406 K410D406-K408 PolarHBondContact O-N 3.41Å; K408-K410 VanDerWaalsContact C-N 3.27Å; K408-K410 WeakPolarHBondContact O-CA 3.43Å; K408-K410 PolarHBondContact O-N 3.47Å
409P46.1Very low52.7Low116 Ų116146.7 Ų146.775%0.75372%0.716SS**  trans-47.2108.2-166.514.1-29.3000104.1D407 R411D407-P409 VanDerWaalsContact C-N 3.31Å; D407-P409 WeakPolarHBondContact O-CA 3.34Å; P409-R411 PolarHBondContact O-N 3.36Å
410K50.8Low51.9Low164 Ų164147.6 Ų147.671%0.71372%0.723SS**  trans-58.1105.2176.1-88.7178.4-179167.8098.4K408 P412K408-K410 VanDerWaalsContact C-N 3.27Å; K408-K410 WeakPolarHBondContact O-CA 3.43Å; K408-K410 PolarHBondContact O-N 3.47Å; K410-P412 WeakPolarHBondContact O-CA 3.26Å; K410-P412 WeakPolarHBondContact O-CD 3.4Å
411R47.7Very low51.3Low221 Ų221150 Ų15083%0.83473%0.732SS**  trans-41.4116.4-178.7-89.7-178.6173.6-178.6-1.6101.9P409 T413P409-R411 PolarHBondContact O-N 3.36Å; R411-T413 VanDerWaalsContact C-N 3.27Å; R411-T413 PolarHBondContact O-N 3.28Å
412P45.6Very low51Low105 Ų105145 Ų14568%0.68271%0.711SS**  trans-52.5113.3-174.917-28.9000102.5K410 R414K410-P412 WeakPolarHBondContact O-CA 3.26Å; K410-P412 WeakPolarHBondContact O-CD 3.4Å; P412-R414 PolarHBondContact O-N 3.05Å
413T51.3Low51.1Low134 Ų134140.8 Ų140.882%0.82269%0.693SS**  trans-68.780.8168.335.90000101.2R411 K415R411-T413 VanDerWaalsContact C-N 3.27Å; R411-T413 PolarHBondContact O-N 3.28Å; T413-K415 PolarHBondContact O-N 3.05Å
414R51.1Low51.6Low184 Ų184130.6 Ų130.669%0.69466%0.658SS**  trans-58.673.8153.2-93.6-177.5164.1175.8-0.8103.4P412 R416P412-R414 PolarHBondContact O-N 3.05Å; R414-R416 HydrophobicContact CB-CG 4.16Å; R414-R416 HydrophobicContact CG-CG 4.25Å; R414-R416 PolarHBondContact O-N 3.33Å
415K53.2Low52Low197 Ų197134.2 Ų134.286%0.85766%0.664SS**  -61.780127.1-69.5-170.9177.8-175.10103.2T413 Q417T413-K415 PolarHBondContact O-N 3.05Å; K415-Q417 VanDerWaalsContact C-N 3.33Å; K415-Q417 PolarHBondContact O-N 3.46Å
416R48.6Very low52.5Low180 Ų180131.7 Ų131.768%0.67965%0.653SS**  trans-51115.2156.3-79174.3175.9171.8-2.2101.9R414 A418R414-R416 HydrophobicContact CB-CG 4.16Å; R414-R416 HydrophobicContact CG-CG 4.25Å; R414-R416 PolarHBondContact O-N 3.33Å; R416-A418 PolarHBondContact O-N 3.07Å; R416-A418 VanDerWaalsContact O-N 3.1Å
417Q50.1Low52.9Low185 Ų185131.7 Ų131.786%0.86466%0.66SS**PPolyproline II helixtrans-49.4124.9158.6-81.9175-400104.7K415K415-Q417 VanDerWaalsContact C-N 3.33Å; K415-Q417 PolarHBondContact O-N 3.46Å
418A49.7Very low53.3Low61 Ų61132.7 Ų132.750%0.50466%0.662SS.*PPolyproline II helixtrans-50.4132.817900000107R416 E420R416-A418 PolarHBondContact O-N 3.07Å; R416-A418 VanDerWaalsContact O-N 3.1Å; A418-E420 PolarHBondContact O-N 2.88Å
419P52.9Low53.8Low73 Ų73127.9 Ų127.947%0.47465%0.648SS.*PPolyproline II helixtrans-48.5133.8178.3-23.831.2000109.2D421 F422P419-D421 PolarHBondContact O-N 3.48Å; P419-F422 HydrophobicContact CB-CD2 4.06Å; P419-F422 HydrophobicContact CB-CE2 4.4Å; P419-F422 HydrophobicContact CG-CD2 4.06Å; P419-F422 HydrophobicContact CG-CE2 4.07Å; P419-F422 PolarHBondContact O-N 3.08Å
420E55.3Low54.6Low159 Ų159127 Ų12774%0.74363%0.632SS**G310 helixtrans-54.5-18-178.1-71-171.616100113A418 F422 L423A418-E420 PolarHBondContact O-N 2.88Å; E420-F422 PolarHBondContact O-N 3.24Å; E420-L423 PolarHBondContact O-N 3.13Å; E420-L423 VanDerWaalsContact O-N 3.16Å
421D58.1Low55.6Low145 Ų145121.7 Ų121.778%0.77561%0.611SS**G310 helixtrans-63.8-20.3172.9-69.2-23.9000114.3P419P419-D421 PolarHBondContact O-N 3.48Å
422F54.8Low56.6Low85 Ų85116.2 Ų116.237%0.37359%0.593SS.*G310 helixtrans-83.2-15175.1-77.2-87.3000112.8P419 E420 I431 F432 M433P419-F422 HydrophobicContact CB-CD2 4.06Å; P419-F422 HydrophobicContact CB-CE2 4.4Å; P419-F422 HydrophobicContact CG-CD2 4.06Å; P419-F422 HydrophobicContact CG-CE2 4.07Å; P419-F422 PolarHBondContact O-N 3.08Å; E420-F422 PolarHBondContact O-N 3.24Å; F422-I431 CarbonylContact O-C 3.56Å; F422-I431 WeakPolarHBondContact O-CA 3.22Å; F422-F432 VanDerWaalsContact CD1-O 3.25Å; F422-F432 WeakPolarHBondContact CD1-O 3.33Å; F422-F432 PolarHBondContact O-N 3.31Å; F422-M433 HydrophobicContact CD1-SD 3.78Å; F422-M433 HydrophobicContact CE1-SD 3.84Å
423L60.6Low57.6Low84 Ų84114 Ų11444%0.4458%0.575SS.*BIsolated β-bridgetrans-101.6116.7-177.7-68.4169000109.6E420 K425 I431E420-L423 PolarHBondContact O-N 3.13Å; E420-L423 VanDerWaalsContact O-N 3.16Å; L423-K425 PolarHBondContact O-N 2.97Å; L423-I431 HydrophobicContact CD2-CG1 4.41Å
424G60.6Low58.5Low12 Ų12111.5 Ų111.512%0.12458%0.576CS.*  trans-58.3127.6174.300000111.7G426 K430G424-G426 PolarHBondContact O-N 3.44Å; G424-K430 PolarHBondContact N-O 3.33Å
425K58.3Low59.8Low200 Ų200107 Ų10787%0.8757%0.566SS**SBendtrans-77.447.4175.5-60-176.3-179.4-178.20111.6L423L423-K425 PolarHBondContact O-N 2.97Å
426G58.8Low61Low42 Ų42104.1 Ų104.143%0.43356%0.56SS.*SBendtrans-114.4170.3176.600000111.6G424 E428G424-G426 PolarHBondContact O-N 3.44Å; G426-E428 PolarHBondContact O-N 3.16Å; G426-E428 VanDerWaalsContact O-N 3.17Å
427P56.8Low62.3Low146 Ų146100.4 Ų100.495%0.94855%0.55SS*.SBendtrans-62.7-18.7178.224.2-32000113.4
428E57.7Low63.6Low123 Ų12395.7 Ų95.758%0.57553%0.531SS*.SBendtrans-111.5127167.5-66.9-176.2161.700110.2G426 K430G426-E428 PolarHBondContact O-N 3.16Å; G426-E428 VanDerWaalsContact O-N 3.17Å; E428-K430 PolarHBondContact O-N 3.35Å; E428-K430 WeakPolarHBondContact OE2-CE 3.15Å; E428-K430 IonicContact OE2-NZ 2.74Å
429P60.9Low64.9Low69 Ų6993.6 Ų93.645%0.44851%0.511SS..  trans-7290.4179.829.4-33.4000110.1
430K64.8Low66.2Low99 Ų9997.6 Ų97.643%0.4352%0.517SS..  trans-88.8131.7174.8-66.5-177.5-176.8-1790110.2G424 E428 F432 N443G424-K430 PolarHBondContact N-O 3.33Å; E428-K430 PolarHBondContact O-N 3.35Å; E428-K430 WeakPolarHBondContact OE2-CE 3.15Å; E428-K430 IonicContact OE2-NZ 2.74Å; K430-F432 PolarHBondContact O-N 3.25Å; K430-N443 WeakPolarHBondContact CA-OD1 3.45Å
431I69.9Low67.2Low52 Ų5294.6 Ų94.627%0.26751%0.506SS..BIsolated β-bridgetrans-83.8112.4176.7-56.2173.4000108.8F422 L423 M433 N443F422-I431 CarbonylContact O-C 3.56Å; F422-I431 WeakPolarHBondContact O-CA 3.22Å; L423-I431 HydrophobicContact CD2-CG1 4.41Å; I431-M433 HydrophobicContact CB-CE 4.39Å; I431-M433 HydrophobicContact CG2-CE 3.36Å; I431-M433 HydrophobicContact CG2-SD 3.94Å; I431-N443 PolarHBondContact N-ND2 2.87Å; I431-N443 PolarHBondContact N-OD1 3.03Å; I431-N443 PolarHBondContact O-ND2 3.34Å
432F69.1Low68Low105 Ų10594.8 Ų94.846%0.46150%0.495SS..  trans-87.3119.3-179.4-79-73.3000111.1F422 K430 T439F422-F432 VanDerWaalsContact CD1-O 3.25Å; F422-F432 WeakPolarHBondContact CD1-O 3.33Å; F422-F432 PolarHBondContact O-N 3.31Å; K430-F432 PolarHBondContact O-N 3.25Å; F432-T439 HydrophobicContact CD1-CG2 3.79Å; F432-T439 HydrophobicContact CE1-CG2 4.17Å
433M66.1Low68.9Low58 Ų5893 Ų9329%0.28649%0.49SS..  trans-109.119.7-176.9-124.562.993.200113.6F422 I431 N435 L438 T439 W442F422-M433 HydrophobicContact CD1-SD 3.78Å; F422-M433 HydrophobicContact CE1-SD 3.84Å; I431-M433 HydrophobicContact CB-CE 4.39Å; I431-M433 HydrophobicContact CG2-CE 3.36Å; I431-M433 HydrophobicContact CG2-SD 3.94Å; M433-N435 PolarHBondContact O-N 2.61Å; M433-L438 HydrophobicContact CB-CB 3.96Å; M433-T439 PolarHBondContact N-OG1 3.12Å; M433-W442 HydrophobicContact CE-CB 3.86Å; M433-W442 HydrophobicContact CE-CD2 3.53Å; M433-W442 HydrophobicContact CE-CE3 4.45Å; M433-W442 HydrophobicContact CE-CG 3.19Å; M433-W442 VanDerWaalsContact CE-NE1 3.32Å
434G70.8Confident69.5Low83 Ų8394.4 Ų94.486%0.85650%0.497SS*.SBendtrans76.4-31.4175.900000115.3
435N79.2Confident69.8Low88 Ų8898.2 Ų98.247%0.47152%0.515SS..SBendtrans-107139.9171.1-176.7-23.7000109.8M433 E437 L438 T439M433-N435 PolarHBondContact O-N 2.61Å; N435-E437 PolarHBondContact O-N 3.17Å; N435-E437 PolarHBondContact OD1-N 2.7Å; N435-E437 VanDerWaalsContact OD1-N 3.17Å; N435-L438 HydrophobicContact CB-CB 4.25Å; N435-L438 HydrophobicContact CB-CD1 4.1Å; N435-L438 HydrophobicContact CB-CG 4.43Å; N435-L438 PolarHBondContact O-N 3.08Å; N435-T439 WeakPolarHBondContact O-CB 3.33Å; N435-T439 PolarHBondContact O-N 3Å; N435-T439 PolarHBondContact O-OG1 2.89Å
436D77Confident70Confident137 Ų13796.1 Ų96.173%0.73351%0.508SS*.Hα-helixtrans-62.9-40.6-176.6-65.6-23.2000112.7T439 R440D436-T439 PolarHBondContact O-N 3.35Å; D436-R440 WeakPolarHBondContact O-CB 3.49Å; D436-R440 PolarHBondContact O-N 2.83Å
437E77.7Confident70.3Confident102 Ų10297.5 Ų97.548%0.47751%0.506SS..Hα-helixtrans-69.5-37.5177.4-75.6-59.8151.500112.2N435 R440 L441N435-E437 PolarHBondContact O-N 3.17Å; N435-E437 PolarHBondContact OD1-N 2.7Å; N435-E437 VanDerWaalsContact OD1-N 3.17Å; E437-R440 PolarHBondContact O-N 3.45Å; E437-R440 IonicContact OE2-CZ 3.84Å; E437-R440 IonicContact OE2-NE 3.98Å; E437-R440 PolarHBondContact OE2-NE 3.44Å; E437-R440 IonicContact OE2-NH2 3.72Å; E437-R440 PolarHBondContact OE2-NH2 2.81Å; E437-L441 WeakPolarHBondContact O-CB 2.97Å; E437-L441 WeakPolarHBondContact O-CG 3.47Å; E437-L441 PolarHBondContact O-N 3.01Å
438L75.5Confident70.8Confident87 Ų8796.3 Ų96.346%0.45549%0.491SS..Hα-helixtrans-69.7-37.3175.4-77.1169000111.2M433 N435 R440 L441 W442M433-L438 HydrophobicContact CB-CB 3.96Å; N435-L438 HydrophobicContact CB-CB 4.25Å; N435-L438 HydrophobicContact CB-CD1 4.1Å; N435-L438 HydrophobicContact CB-CG 4.43Å; N435-L438 PolarHBondContact O-N 3.08Å; L438-R440 VanDerWaalsContact C-N 3.33Å; L438-L441 PolarHBondContact O-N 3.19Å; L438-W442 VanDerWaalsContact O-CB 3.27Å; L438-W442 WeakPolarHBondContact O-CB 3.38Å; L438-W442 PolarHBondContact O-N 3.42Å
439T78.4Confident71.1Confident16 Ų1696.5 Ų96.510%0.09849%0.494CS..Hα-helixtrans-64.7-39.6173.3-57.80000110.4F432 M433 N435 D436 N443F432-T439 HydrophobicContact CD1-CG2 3.79Å; F432-T439 HydrophobicContact CE1-CG2 4.17Å; M433-T439 PolarHBondContact N-OG1 3.12Å; N435-T439 WeakPolarHBondContact O-CB 3.33Å; N435-T439 PolarHBondContact O-N 3Å; N435-T439 PolarHBondContact O-OG1 2.89Å; D436-T439 PolarHBondContact O-N 3.35Å; T439-N443 WeakPolarHBondContact O-CB 3.41Å; T439-N443 PolarHBondContact O-N 3.2Å; T439-N443 PolarHBondContact O-ND2 3.43Å
440R80.3Confident71.4Confident158 Ų15899.4 Ų99.460%0.59650%0.501SS*.Hα-helixtrans-62.4-53174.1-173.1176.974.2132.7-2.7111.6D436 E437 L438 W442 N443 L444D436-R440 WeakPolarHBondContact O-CB 3.49Å; D436-R440 PolarHBondContact O-N 2.83Å; E437-R440 PolarHBondContact O-N 3.45Å; E437-R440 IonicContact OE2-CZ 3.84Å; E437-R440 IonicContact OE2-NE 3.98Å; E437-R440 PolarHBondContact OE2-NE 3.44Å; E437-R440 IonicContact OE2-NH2 3.72Å; E437-R440 PolarHBondContact OE2-NH2 2.81Å; L438-R440 VanDerWaalsContact C-N 3.33Å; R440-W442 VanDerWaalsContact C-N 3.29Å; R440-W442 PolarHBondContact O-N 3.26Å; R440-N443 PolarHBondContact O-N 3.41Å; R440-L444 PolarHBondContact O-N 3.22Å
441L76.1Confident71.5Confident96 Ų9695.2 Ų95.250%0.50349%0.485SS..Hα-helixtrans-60.7-38.6-177.9-72.4173.5000112.5E437 L438 N443 L444E437-L441 WeakPolarHBondContact O-CB 2.97Å; E437-L441 WeakPolarHBondContact O-CG 3.47Å; E437-L441 PolarHBondContact O-N 3.01Å; L438-L441 PolarHBondContact O-N 3.19Å; L441-N443 VanDerWaalsContact C-N 3.3Å; L441-N443 PolarHBondContact O-N 3.02Å; L441-L444 HydrophobicContact CD2-CD1 3.84Å
442W74.3Confident71.2Confident148 Ų14896.4 Ų96.456%0.56150%0.497SS*.Hα-helixtrans-78.7-14.9-177.2-145.9-95.4000114.1M433 L438 R440M433-W442 HydrophobicContact CE-CB 3.86Å; M433-W442 HydrophobicContact CE-CD2 3.53Å; M433-W442 HydrophobicContact CE-CE3 4.45Å; M433-W442 HydrophobicContact CE-CG 3.19Å; M433-W442 VanDerWaalsContact CE-NE1 3.32Å; L438-W442 VanDerWaalsContact O-CB 3.27Å; L438-W442 WeakPolarHBondContact O-CB 3.38Å; L438-W442 PolarHBondContact O-N 3.42Å; R440-W442 VanDerWaalsContact C-N 3.29Å; R440-W442 PolarHBondContact O-N 3.26Å
443N74.8Confident71.2Confident49 Ų4999.3 Ų99.326%0.26251%0.509SS..THydrogen-bonded Turntrans-106.810.5176.4-66.7-56.1000113K430 I431 T439 R440 L441 N445K430-N443 WeakPolarHBondContact CA-OD1 3.45Å; I431-N443 PolarHBondContact N-ND2 2.87Å; I431-N443 PolarHBondContact N-OD1 3.03Å; I431-N443 PolarHBondContact O-ND2 3.34Å; T439-N443 WeakPolarHBondContact O-CB 3.41Å; T439-N443 PolarHBondContact O-N 3.2Å; T439-N443 PolarHBondContact O-ND2 3.43Å; R440-N443 PolarHBondContact O-N 3.41Å; L441-N443 VanDerWaalsContact C-N 3.3Å; L441-N443 PolarHBondContact O-N 3.02Å; N443-N445 PolarHBondContact O-N 3.46Å
444L72.1Confident71.4Confident112 Ų11299 Ų9959%0.58651%0.514SS*.SBendtrans-59.5-36.1174.8-84164.5000112.1R440 L441R440-L444 PolarHBondContact O-N 3.22Å; L441-L444 HydrophobicContact CD2-CD1 3.84Å
445N66.5Low71.1Confident92 Ų92103.2 Ų103.249%0.49251%0.511SS..  trans-152140.8172.4-72.7-62.6000109.3N443 A451N443-N445 PolarHBondContact O-N 3.46Å; N445-A451 HydrophobicContact CB-CB 3.72Å; N445-A451 WeakPolarHBondContact ND2-CB 3.43Å
446Q62.1Low70.5Confident157 Ų157103.5 Ų103.573%0.73452%0.52SS*.SBendtrans-71.2-33.4-179.1-72.5-177.57.300112.9
447D65.6Low70Confident71 Ų71103.4 Ų103.438%0.3851%0.509SS..  trans-119.8124.6174.3-172.22.7000111M449 E450 A451D447-M449 PolarHBondContact O-N 3.45Å; D447-M449 PolarHBondContact OD1-N 2.92Å; D447-E450 HydrophobicContact CB-CB 4.13Å; D447-E450 HydrophobicContact CB-CG 4.05Å; D447-E450 PolarHBondContact O-N 2.7Å; D447-A451 PolarHBondContact O-N 3.46Å
448N68.1Low69.5Low121 Ų121104.8 Ų104.865%0.64752%0.516SS*.Hα-helixtrans-62.3-29.6175.4-72.5-34.8000111.8C452N448-C452 PolarHBondContact O-N 2.71Å; N448-C452 VanDerWaalsContact O-N 3.15Å; N448-C452 PolarHBondContact O-SG 2.85Å
449M64.6Low69.2Low127 Ų127109 Ų10963%0.62653%0.531SS*.Hα-helixtrans-73.8-36.2178.2-66.1-61.2-64.600111.9D447 C452 K453D447-M449 PolarHBondContact O-N 3.45Å; D447-M449 PolarHBondContact OD1-N 2.92Å; M449-C452 PolarHBondContact O-N 3.12Å; M449-K453 PolarHBondContact O-N 3.14Å
450E66.7Low68.8Low129 Ų129111.5 Ų111.560%0.60354%0.542SS*.Hα-helixtrans-71.4-39172.8-68.8-174.5161.100111.6D447 C452 K453D447-E450 HydrophobicContact CB-CB 4.13Å; D447-E450 HydrophobicContact CB-CG 4.05Å; D447-E450 PolarHBondContact O-N 2.7Å; E450-C452 PolarHBondContact O-N 3.4Å; E450-K453 WeakPolarHBondContact O-CB 3.3Å; E450-K453 PolarHBondContact O-N 3.38Å
451A66Low68.7Low11 Ų11106.2 Ų106.29%0.09153%0.528CS..Hα-helixtrans-56.3-35.5171.600000112.3N445 D447 K453 S454 R457N445-A451 HydrophobicContact CB-CB 3.72Å; N445-A451 WeakPolarHBondContact ND2-CB 3.43Å; D447-A451 PolarHBondContact O-N 3.46Å; A451-K453 VanDerWaalsContact C-N 3.26Å; A451-K453 PolarHBondContact O-N 2.92Å; A451-S454 PolarHBondContact O-N 3.05Å; A451-R457 WeakPolarHBondContact O-CD 3.4Å
452C65.2Low68.8Low78 Ų78104.3 Ų104.353%0.52752%0.523SS..THydrogen-bonded Turntrans-74.8-10.7176.5-66.90000114.3N448 M449 E450 R457N448-C452 PolarHBondContact O-N 2.71Å; N448-C452 VanDerWaalsContact O-N 3.15Å; N448-C452 PolarHBondContact O-SG 2.85Å; M449-C452 PolarHBondContact O-N 3.12Å; E450-C452 PolarHBondContact O-N 3.4Å; C452-R457 PolarHBondContact SG-NH1 3.31Å
453K68.3Low68.8Low165 Ų16598.5 Ų98.572%0.71750%0.502SS*.THydrogen-bonded Turntrans-96.8-1.4175.8-68.4173.6177.8175.50113.4M449 E450 A451 E455M449-K453 PolarHBondContact O-N 3.14Å; E450-K453 WeakPolarHBondContact O-CB 3.3Å; E450-K453 PolarHBondContact O-N 3.38Å; A451-K453 VanDerWaalsContact C-N 3.26Å; A451-K453 PolarHBondContact O-N 2.92Å; K453-E455 PolarHBondContact O-N 3.33Å
454S69.4Low68.8Low53 Ų53100.1 Ų100.137%0.37151%0.511SS..  trans-61.4133.8177.5-179.50000111.1A451 S456 R457A451-S454 PolarHBondContact O-N 3.05Å; S454-S456 PolarHBondContact O-N 3.12Å; S454-S456 PolarHBondContact OG-N 2.69Å; S454-S456 PolarHBondContact OG-OG 2.79Å; S454-R457 WeakPolarHBondContact O-CB 3.41Å; S454-R457 PolarHBondContact O-N 2.85Å
455E65.8Low69Low170 Ų170101.6 Ų101.679%0.79452%0.515SS*.G310 helixtrans-57.7-28.5175.1-66.1-179.8173.100112.2K453 R457 E458K453-E455 PolarHBondContact O-N 3.33Å; E455-R457 PolarHBondContact O-N 3.02Å; E455-R457 VanDerWaalsContact O-N 3.14Å; E455-E458 WeakPolarHBondContact O-CB 2.91Å; E455-E458 PolarHBondContact O-N 2.74Å
456S65.8Low69.7Low95 Ų9598.8 Ų98.866%0.66450%0.498SS*.G310 helixtrans-62.3-18.2173.368.40000114.3S454S454-S456 PolarHBondContact O-N 3.12Å; S454-S456 PolarHBondContact OG-N 2.69Å; S454-S456 PolarHBondContact OG-OG 2.79Å
457R66.2Low70.5Confident135 Ų13591.3 Ų91.351%0.50946%0.464SS..G310 helixtrans-99.10174.7-73.7-169.9163.4-163.7-3.6113.3A451 C452 S454 E455 F459A451-R457 WeakPolarHBondContact O-CD 3.4Å; C452-R457 PolarHBondContact SG-NH1 3.31Å; S454-R457 WeakPolarHBondContact O-CB 3.41Å; S454-R457 PolarHBondContact O-N 2.85Å; E455-R457 PolarHBondContact O-N 3.02Å; E455-R457 VanDerWaalsContact O-N 3.14Å; R457-F459 HydrophobicContact CB-CE2 4.15Å; R457-F459 HydrophobicContact CB-CZ 4.38Å; R457-F459 HydrophobicContact CG-CE2 4.36Å; R457-F459 HydrophobicContact CG-CZ 4.23Å; R457-F459 WeakPolarHBondContact O-CD2 3.1Å; R457-F459 WeakPolarHBondContact O-CE2 3.32Å; R457-F459 PolarHBondContact O-N 3.36Å
458E67.6Low71.1Confident131 Ų13190 Ų9061%0.61246%0.463SS*.  trans-74.379164.6-68.3-157.2172.200109.5E455 M460 R503E455-E458 WeakPolarHBondContact O-CB 2.91Å; E455-E458 PolarHBondContact O-N 2.74Å; E458-M460 PolarHBondContact O-N 3Å; E458-R503 IonicContact OE2-NH2 3.42Å
459F68.9Low71.4Confident175 Ų17589.3 Ų89.377%0.76846%0.455SS*.  trans-70.37.6176.6-53.5-72.7000113.7R457 P461R457-F459 HydrophobicContact CB-CE2 4.15Å; R457-F459 HydrophobicContact CB-CZ 4.38Å; R457-F459 HydrophobicContact CG-CE2 4.36Å; R457-F459 HydrophobicContact CG-CZ 4.23Å; R457-F459 WeakPolarHBondContact O-CD2 3.1Å; R457-F459 WeakPolarHBondContact O-CE2 3.32Å; R457-F459 PolarHBondContact O-N 3.36Å; F459-P461 WeakPolarHBondContact O-CD 3.22Å
460M71.5Confident71.9Confident68 Ų6883.3 Ų83.334%0.33543%0.426SS..  trans-92.7110.7-177.7-175.1174.1-64.200109E458 L499 R503E458-M460 PolarHBondContact O-N 3Å; M460-L499 HydrophobicContact CG-CD1 3.57Å; M460-L499 HydrophobicContact SD-CD1 3.97Å; M460-R503 HydrophobicContact SD-CG 4.07Å
461P77.2Confident72.3Confident47 Ų4779 Ų7931%0.30541%0.407SS..  trans-65.7156.3178.728.9-34.9000110.8F459 F466 L499F459-P461 WeakPolarHBondContact O-CD 3.22Å; P461-F466 HydrophobicContact CB-CB 4.24Å; P461-F466 HydrophobicContact CG-CB 4.07Å; P461-F466 HydrophobicContact CG-CD2 3.97Å; P461-F466 HydrophobicContact CG-CG 4.32Å; P461-L499 HydrophobicContact CG-CD2 4.39Å
462S78.6Confident72.6Confident56 Ų5684.6 Ų84.639%0.39243%0.431SS..  trans-65.9157.4171.669.90000110.8D464 E465 F466S462-D464 PolarHBondContact O-N 3.27Å; S462-E465 WeakPolarHBondContact OG-CB 3.49Å; S462-E465 PolarHBondContact OG-N 3.01Å; S462-F466 WeakPolarHBondContact O-CB 3.48Å; S462-F466 PolarHBondContact O-N 3.44Å; S462-F466 VanDerWaalsContact O-N 3.11Å
463L74.6Confident72.8Confident26 Ų2682.5 Ų82.514%0.13641%0.414CS..Hα-helixtrans-61.4-37.6176-73.8172.3000110.7F467 L499 L500 R503 L529L463-F467 HydrophobicContact CD2-CD2 4.15Å; L463-F467 HydrophobicContact CD2-CE2 3.82Å; L463-F467 WeakPolarHBondContact O-CB 3.42Å; L463-F467 VanDerWaalsContact O-CD2 3.31Å; L463-F467 WeakPolarHBondContact O-CD2 3.34Å; L463-F467 PolarHBondContact O-N 3.38Å; L463-L499 HydrophobicContact CD2-CD2 3.99Å; L463-L499 HydrophobicContact CD2-CG 3.82Å; L463-L500 HydrophobicContact CD2-CD2 4.04Å; L463-R503 HydrophobicContact CD1-CB 3.8Å; L463-R503 HydrophobicContact CD2-CB 4.25Å; L463-R503 HydrophobicContact CG-CB 3.92Å; L463-L529 HydrophobicContact CD1-CD2 4.44Å
464D73.7Confident72.6Confident83 Ų8376.2 Ų76.244%0.44439%0.392SS..Hα-helixtrans-67.7-45.9-176-56-17.8000111.1S462 A468 L533S462-D464 PolarHBondContact O-N 3.27Å; D464-A468 WeakPolarHBondContact O-CB 3.42Å; D464-A468 PolarHBondContact O-N 2.9Å; D464-L533 HydrophobicContact CB-CD2 3.96Å; D464-L533 WeakPolarHBondContact OD1-CD1 3.43Å
465E77.6Confident72.6Confident144 Ų14477.5 Ų77.567%0.67340%0.395SS*.Hα-helixtrans-71.3-39.5-179.4-165.6179.3-164.100112.4S462S462-E465 WeakPolarHBondContact OG-CB 3.49Å; S462-E465 PolarHBondContact OG-N 3.01Å
466F79.8Confident72.3Confident32 Ų3275 Ų7514%0.1439%0.393CS..Hα-helixtrans-74-31.7-179.5-175.3-94.7000113.5P461 S462 Y492 R495 A496 L499P461-F466 HydrophobicContact CB-CB 4.24Å; P461-F466 HydrophobicContact CG-CB 4.07Å; P461-F466 HydrophobicContact CG-CD2 3.97Å; P461-F466 HydrophobicContact CG-CG 4.32Å; S462-F466 WeakPolarHBondContact O-CB 3.48Å; S462-F466 PolarHBondContact O-N 3.44Å; S462-F466 VanDerWaalsContact O-N 3.11Å; F466-Y492 HydrophobicContact CD1-CE2 4.32Å; F466-Y492 HydrophobicContact CE1-CD2 4.2Å; F466-Y492 HydrophobicContact CE1-CE1 4.33Å; F466-Y492 AromaticContact CE1-CE2 3.59Å; F466-Y492 HydrophobicContact CE1-CE2 3.59Å; F466-Y492 AromaticContact CE1-CZ 3.67Å; F466-Y492 HydrophobicContact CE2-CE2 4.16Å; F466-Y492 AromaticContact CZ-CD2 3.77Å; F466-Y492 HydrophobicContact CZ-CD2 3.77Å; F466-Y492 AromaticContact CZ-CE2 3.49Å; F466-Y492 HydrophobicContact CZ-CE2 3.49Å; F466-Y492 VanDerWaalsContact CZ-CE2 3.49Å; F466-Y492 PolarHBondContact O-OH 3.05Å; F466-R495 HydrophobicContact CE2-CB 4.41Å; F466-R495 HydrophobicContact CZ-CB 3.79Å; F466-A496 HydrophobicContact CE1-CB 3.91Å; F466-L499 HydrophobicContact CB-CD2 3.63Å; F466-L499 HydrophobicContact CD1-CD2 3.71Å; F466-L499 HydrophobicContact CG-CD2 3.68Å
467F80.1Confident71.8Confident1 Ų175.9 Ų75.90%0.00440%0.395CS..Hα-helixtrans-97.7-3.2179.8-72.4-76.2000113.9L463 E469 A470 I471 Y492 A496 L499 L500 V526 L529L463-F467 HydrophobicContact CD2-CD2 4.15Å; L463-F467 HydrophobicContact CD2-CE2 3.82Å; L463-F467 WeakPolarHBondContact O-CB 3.42Å; L463-F467 VanDerWaalsContact O-CD2 3.31Å; L463-F467 WeakPolarHBondContact O-CD2 3.34Å; L463-F467 PolarHBondContact O-N 3.38Å; F467-E469 VanDerWaalsContact C-N 3.35Å; F467-E469 PolarHBondContact O-N 2.59Å; F467-A470 HydrophobicContact CD1-CB 4.27Å; F467-A470 CarbonylContact O-C 3.57Å; F467-A470 WeakPolarHBondContact O-CA 3.47Å; F467-A470 PolarHBondContact O-N 2.9Å; F467-I471 HydrophobicContact CB-CD1 4.07Å; F467-I471 HydrophobicContact CB-CG1 4.31Å; F467-I471 WeakPolarHBondContact O-CB 3.24Å; F467-I471 VanDerWaalsContact O-CG1 3.24Å; F467-I471 WeakPolarHBondContact O-CG1 3.31Å; F467-I471 PolarHBondContact O-N 2.85Å; F467-Y492 WeakPolarHBondContact CD1-OH 3.35Å; F467-Y492 HydrophobicContact CE1-CE1 4.38Å; F467-A496 HydrophobicContact CE1-CB 3.65Å; F467-A496 HydrophobicContact CZ-CB 3.56Å; F467-L499 HydrophobicContact CE2-CD2 4.29Å; F467-L500 HydrophobicContact CE2-CD2 3.78Å; F467-L500 HydrophobicContact CE2-CG 3.93Å; F467-L500 HydrophobicContact CZ-CD1 3.85Å; F467-L500 HydrophobicContact CZ-CD2 3.93Å; F467-L500 HydrophobicContact CZ-CG 3.7Å; F467-V526 HydrophobicContact CD1-CG2 3.65Å; F467-V526 HydrophobicContact CE1-CG2 4.01Å; F467-L529 HydrophobicContact CD2-CD1 4.14Å; F467-L529 HydrophobicContact CE2-CD1 4.38Å; F467-L529 HydrophobicContact CG-CD1 4.49Å
468A77Confident71.5Confident43 Ų4373.6 Ų73.636%0.35539%0.392SS..Hα-helixtrans-48.8-51.8178.700000112.8D464 A470 I471 E472D464-A468 WeakPolarHBondContact O-CB 3.42Å; D464-A468 PolarHBondContact O-N 2.9Å; A468-A470 VanDerWaalsContact C-N 3.34Å; A468-A470 PolarHBondContact O-N 3.02Å; A468-I471 PolarHBondContact O-N 3.14Å; A468-E472 WeakPolarHBondContact O-CG 3.38Å; A468-E472 PolarHBondContact O-N 3.38Å
469E75.9Confident71Confident106 Ų10675.7 Ų75.750%0.49541%0.405SS..Hα-helixtrans-62.6-38.9178.4-173.2-176.2176.200112.3F467 Q473 V486F467-E469 VanDerWaalsContact C-N 3.35Å; F467-E469 PolarHBondContact O-N 2.59Å; E469-Q473 WeakPolarHBondContact O-CB 3.22Å; E469-Q473 WeakPolarHBondContact O-CG 3.49Å; E469-Q473 PolarHBondContact O-N 2.96Å; E469-Q473 PolarHBondContact OE1-NE2 3.41Å; E469-V486 HydrophobicContact CG-CG2 4.37Å; E469-V486 WeakPolarHBondContact OE1-CG2 3.35Å
470A73.6Confident70.5Confident2 Ų270.1 Ų70.12%0.01739%0.385CS..Hα-helixtrans-72.2-31.4177.700000112.5F467 A468 A474 V487 Y492 V526F467-A470 HydrophobicContact CD1-CB 4.27Å; F467-A470 CarbonylContact O-C 3.57Å; F467-A470 WeakPolarHBondContact O-CA 3.47Å; F467-A470 PolarHBondContact O-N 2.9Å; A468-A470 VanDerWaalsContact C-N 3.34Å; A468-A470 PolarHBondContact O-N 3.02Å; A470-A474 VanDerWaalsContact O-CB 3.3Å; A470-A474 WeakPolarHBondContact O-CB 2.88Å; A470-A474 PolarHBondContact O-N 3.48Å; A470-A474 VanDerWaalsContact O-N 3.1Å; A470-V487 HydrophobicContact CB-CG2 4Å; A470-Y492 HydrophobicContact CB-CE1 4.31Å; A470-Y492 WeakPolarHBondContact CB-OH 3.46Å; A470-V526 HydrophobicContact CB-CG1 4.31Å; A470-V526 HydrophobicContact CB-CG2 4.16Å
471I74.9Confident70Confident39 Ų3973.2 Ų73.220%0.240%0.398CS..Hα-helixtrans-71.4-44.2175.5-68.3167.3000109.8F467 A468 Q473 A474 D475 V526 A530F467-I471 HydrophobicContact CB-CD1 4.07Å; F467-I471 HydrophobicContact CB-CG1 4.31Å; F467-I471 WeakPolarHBondContact O-CB 3.24Å; F467-I471 VanDerWaalsContact O-CG1 3.24Å; F467-I471 WeakPolarHBondContact O-CG1 3.31Å; F467-I471 PolarHBondContact O-N 2.85Å; A468-I471 PolarHBondContact O-N 3.14Å; I471-Q473 PolarHBondContact O-N 3.46Å; I471-A474 PolarHBondContact O-N 3.15Å; I471-A474 VanDerWaalsContact O-N 3.17Å; I471-D475 PolarHBondContact O-N 3.29Å; I471-V526 HydrophobicContact CB-CG1 4.37Å; I471-V526 HydrophobicContact CG1-CG1 3.68Å; I471-A530 HydrophobicContact CG1-CB 4.26Å; I471-A530 HydrophobicContact CG2-CB 3.76Å
472E72.6Confident69.2Low127 Ų12776.7 Ų76.759%0.59341%0.41SS*.Hα-helixtrans-62.8-39.9174.8-74.5-176.4173.900112.4A468 A474 D475 N478A468-E472 WeakPolarHBondContact O-CG 3.38Å; A468-E472 PolarHBondContact O-N 3.38Å; E472-A474 VanDerWaalsContact C-N 3.27Å; E472-A474 PolarHBondContact O-N 3.46Å; E472-D475 PolarHBondContact O-N 3.36Å; E472-N478 PolarHBondContact O-ND2 3.17Å
473Q70.3Confident68.2Low35 Ų3581.3 Ų81.316%0.16443%0.426CS..Hα-helixtrans-72.4-18.2175.4-70.7173.111.100113.6E469 I471 V480 V486E469-Q473 WeakPolarHBondContact O-CB 3.22Å; E469-Q473 WeakPolarHBondContact O-CG 3.49Å; E469-Q473 PolarHBondContact O-N 2.96Å; E469-Q473 PolarHBondContact OE1-NE2 3.41Å; I471-Q473 PolarHBondContact O-N 3.46Å; Q473-V480 HydrophobicContact CG-CG2 4.35Å; Q473-V486 VanDerWaalsContact NE2-CG2 3.32Å; Q473-V486 VanDerWaalsContact OE1-CG2 3.27Å
474A64.7Low67.8Low32 Ų3288 Ų8826%0.26445%0.451SS..Hα-helixtrans-84.3-14.117500000112.8A470 I471 E472 P476 V526A470-A474 VanDerWaalsContact O-CB 3.3Å; A470-A474 WeakPolarHBondContact O-CB 2.88Å; A470-A474 PolarHBondContact O-N 3.48Å; A470-A474 VanDerWaalsContact O-N 3.1Å; I471-A474 PolarHBondContact O-N 3.15Å; I471-A474 VanDerWaalsContact O-N 3.17Å; E472-A474 VanDerWaalsContact C-N 3.27Å; E472-A474 PolarHBondContact O-N 3.46Å; A474-P476 WeakPolarHBondContact O-CD 3.12Å; A474-V526 HydrophobicContact CB-CG1 4.16Å
475D67.8Low67.7Low81 Ų8186.2 Ų86.243%0.43344%0.439SS..SBendtrans-72.3122.4175.6-163.6-35000110.8I471 E472 V477 N478I471-D475 PolarHBondContact O-N 3.29Å; E472-D475 PolarHBondContact O-N 3.36Å; D475-V477 PolarHBondContact O-N 2.83Å; D475-V477 WeakPolarHBondContact OD1-CG2 3.41Å; D475-V477 PolarHBondContact OD1-N 3.11Å; D475-V477 VanDerWaalsContact OD1-N 3.12Å; D475-N478 PolarHBondContact O-N 3.2Å
476P60.3Low67.3Low116 Ų11680.6 Ų80.675%0.75341%0.414SS*.G310 helixtrans-57.6-17.4179.6-24.633.6000115.5A474A474-P476 WeakPolarHBondContact O-CD 3.12Å
477V55.4Low67Low115 Ų11579.3 Ų79.370%0.69741%0.409SS*.G310 helixtrans-74.2-28.7-179.6179.60000112.4D475 M479D475-V477 PolarHBondContact O-N 2.83Å; D475-V477 WeakPolarHBondContact OD1-CG2 3.41Å; D475-V477 PolarHBondContact OD1-N 3.11Å; D475-V477 VanDerWaalsContact OD1-N 3.12Å; V477-M479 VanDerWaalsContact C-N 3.3Å; V477-M479 PolarHBondContact O-N 3.26Å
478N60.3Low66.6Low86 Ų8684.5 Ų84.546%0.4643%0.428SS..G310 helixtrans-82.3-1.6-173.6-74.5-21.9000114.5E472 D475 V480E472-N478 PolarHBondContact O-ND2 3.17Å; D475-N478 PolarHBondContact O-N 3.2Å; N478-V480 HydrophobicContact CB-CG2 4.36Å; N478-V480 PolarHBondContact O-N 2.96Å
479M57.3Low66.7Low176 Ų17686.3 Ų86.387%0.86743%0.432SS*.  trans43.141.2174-64.2-153.2176.700115.5V477V477-M479 VanDerWaalsContact C-N 3.3Å; V477-M479 PolarHBondContact O-N 3.26Å
480V58.2Low66.6Low58 Ų5885.5 Ų85.535%0.35244%0.436SS..  trans-82.1124.5176.4-176.30000110.1Q473 N478Q473-V480 HydrophobicContact CG-CG2 4.35Å; N478-V480 HydrophobicContact CB-CG2 4.36Å; N478-V480 PolarHBondContact O-N 2.96Å
481E59.3Low66.9Low133 Ų13391.2 Ų91.262%0.62147%0.466SS*.  trans-60.4139.9175.8-73.9179177.200111.4E483 Y484E481-E483 PolarHBondContact O-N 3.45Å; E481-Y484 HydrophobicContact CB-CD2 4Å; E481-Y484 PolarHBondContact O-N 3.36Å
482E60.9Low67.2Low119 Ų11990.5 Ų90.556%0.55646%0.461SS*.THydrogen-bonded Turntrans-57.7-25.2-173-74.7-170.7178.400114.6Y484 R488E482-Y484 VanDerWaalsContact C-N 3.34Å; E482-R488 WeakPolarHBondContact O-CD 3.24Å; E482-R488 PolarHBondContact O-NH1 3.42Å; E482-R488 IonicContact OE2-CZ 3.28Å; E482-R488 IonicContact OE2-NH1 3.08Å; E482-R488 IonicContact OE2-NH2 2.69Å; E482-R488 PolarHBondContact OE2-NH2 3.45Å
483E59Low67.6Low154 Ų15484.5 Ų84.572%0.7243%0.434SS*.THydrogen-bonded Turntrans-73.7-25.4-179.4-64.6-177173.800113E481E481-E483 PolarHBondContact O-N 3.45Å
484Y65.1Low68.1Low167 Ų16789.5 Ų89.566%0.65545%0.451SS*.SBendtrans-96.80.8-178.1-64.8-82.5000113.4E481 E482 V486E481-Y484 HydrophobicContact CB-CD2 4Å; E481-Y484 PolarHBondContact O-N 3.36Å; E482-Y484 VanDerWaalsContact C-N 3.34Å; Y484-V486 PolarHBondContact O-N 2.98Å
485K70.8Confident68.9Low45 Ų4595.3 Ų95.320%0.19647%0.466CS..  trans-63.9128.3175.4-70.6-175.6174.8-176.20110.8V487 R488K485-V487 PolarHBondContact O-N 2.9Å; K485-V487 VanDerWaalsContact O-N 3.1Å; K485-R488 PolarHBondContact O-N 3.28Å
486V70.7Confident69.6Low25 Ų2591.5 Ų91.515%0.15245%0.446CS..G310 helixtrans-60.6-26.6-178.4175.40000111.8E469 Q473 Y484 R488 N489 Y492E469-V486 HydrophobicContact CG-CG2 4.37Å; E469-V486 WeakPolarHBondContact OE1-CG2 3.35Å; Q473-V486 VanDerWaalsContact NE2-CG2 3.32Å; Q473-V486 VanDerWaalsContact OE1-CG2 3.27Å; Y484-V486 PolarHBondContact O-N 2.98Å; V486-R488 PolarHBondContact O-N 3.28Å; V486-N489 WeakPolarHBondContact O-CB 3.45Å; V486-N489 PolarHBondContact O-N 3.05Å; V486-Y492 HydrophobicContact CG1-CD1 3.6Å; V486-Y492 HydrophobicContact CG1-CD2 3.32Å; V486-Y492 HydrophobicContact CG1-CE1 3.84Å; V486-Y492 HydrophobicContact CG1-CE2 3.59Å; V486-Y492 HydrophobicContact CG1-CG 3.32Å; V486-Y492 WeakPolarHBondContact O-CB 3.35Å; V486-Y492 WeakPolarHBondContact O-CD1 3.28Å
487V71.9Confident70.6Confident6 Ų687.8 Ų87.84%0.03642%0.419CS..G310 helixtrans-60.9-27.3174.4179.20000113.6A470 K485 A519 L522A470-V487 HydrophobicContact CB-CG2 4Å; K485-V487 PolarHBondContact O-N 2.9Å; K485-V487 VanDerWaalsContact O-N 3.1Å; V487-A519 HydrophobicContact CG1-CB 4.29Å; V487-A519 WeakPolarHBondContact CG1-O 3.39Å; V487-L522 HydrophobicContact CG1-CB 3.35Å; V487-L522 HydrophobicContact CG1-CD1 4.2Å; V487-L522 HydrophobicContact CG1-CG 4.42Å
488R72.2Confident71.9Confident109 Ų10990 Ų9041%0.41142%0.415SS..G310 helixtrans-84.2-12.7175.3-75.6-169.3174.71642.1113.5E482 K485 V486 P490 A519E482-R488 WeakPolarHBondContact O-CD 3.24Å; E482-R488 PolarHBondContact O-NH1 3.42Å; E482-R488 IonicContact OE2-CZ 3.28Å; E482-R488 IonicContact OE2-NH1 3.08Å; E482-R488 IonicContact OE2-NH2 2.69Å; E482-R488 PolarHBondContact OE2-NH2 3.45Å; K485-R488 PolarHBondContact O-N 3.28Å; V486-R488 PolarHBondContact O-N 3.28Å; R488-P490 WeakPolarHBondContact O-CD 3.27Å; R488-A519 HydrophobicContact CG-CB 3.82Å
489N79.3Confident72.9Confident81 Ų8186.5 Ų86.543%0.43340%0.396SS..  trans-69121.4174.5-174.4-30.3000109.7V486 N491 Y492 G493V486-N489 WeakPolarHBondContact O-CB 3.45Å; V486-N489 PolarHBondContact O-N 3.05Å; N489-N491 VanDerWaalsContact C-N 3.29Å; N489-N491 PolarHBondContact O-N 3.25Å; N489-N491 PolarHBondContact OD1-N 3.18Å; N489-Y492 PolarHBondContact O-N 3.19Å; N489-G493 PolarHBondContact O-N 2.97Å
490P74.4Confident74Confident90 Ų9078.1 Ų78.158%0.58436%0.355SS*.Hα-helixtrans-57.6-39.2-177-24.933.7000113.5R488 G493 W494R488-P490 WeakPolarHBondContact O-CD 3.27Å; P490-G493 PolarHBondContact O-N 2.94Å; P490-W494 PolarHBondContact O-N 3.18Å
491N78.9Confident75Confident121 Ų12177.3 Ų77.365%0.64735%0.352SS*.Hα-helixtrans-70-40.2-178.2-74.3-26.2000111.7N489 R495N489-N491 VanDerWaalsContact C-N 3.29Å; N489-N491 PolarHBondContact O-N 3.25Å; N489-N491 PolarHBondContact OD1-N 3.18Å; N491-R495 VanDerWaalsContact O-CG 3.28Å; N491-R495 WeakPolarHBondContact O-CG 3.27Å; N491-R495 PolarHBondContact O-N 3.01Å
492Y82.7Confident75.9Confident24 Ų2480 Ų809%0.09436%0.357CS..Hα-helixtrans-65.4-46.6173.8-176.3-93.8000110.5F466 F467 A470 V486 N489 W494 R495 A496F466-Y492 HydrophobicContact CD1-CE2 4.32Å; F466-Y492 HydrophobicContact CE1-CD2 4.2Å; F466-Y492 HydrophobicContact CE1-CE1 4.33Å; F466-Y492 AromaticContact CE1-CE2 3.59Å; F466-Y492 HydrophobicContact CE1-CE2 3.59Å; F466-Y492 AromaticContact CE1-CZ 3.67Å; F466-Y492 HydrophobicContact CE2-CE2 4.16Å; F466-Y492 AromaticContact CZ-CD2 3.77Å; F466-Y492 HydrophobicContact CZ-CD2 3.77Å; F466-Y492 AromaticContact CZ-CE2 3.49Å; F466-Y492 HydrophobicContact CZ-CE2 3.49Å; F466-Y492 VanDerWaalsContact CZ-CE2 3.49Å; F466-Y492 PolarHBondContact O-OH 3.05Å; F467-Y492 WeakPolarHBondContact CD1-OH 3.35Å; F467-Y492 HydrophobicContact CE1-CE1 4.38Å; A470-Y492 HydrophobicContact CB-CE1 4.31Å; A470-Y492 WeakPolarHBondContact CB-OH 3.46Å; V486-Y492 HydrophobicContact CG1-CD1 3.6Å; V486-Y492 HydrophobicContact CG1-CD2 3.32Å; V486-Y492 HydrophobicContact CG1-CE1 3.84Å; V486-Y492 HydrophobicContact CG1-CE2 3.59Å; V486-Y492 HydrophobicContact CG1-CG 3.32Å; V486-Y492 WeakPolarHBondContact O-CB 3.35Å; V486-Y492 WeakPolarHBondContact O-CD1 3.28Å; N489-Y492 PolarHBondContact O-N 3.19Å; Y492-W494 VanDerWaalsContact C-N 3.32Å; Y492-W494 PolarHBondContact O-N 2.89Å; Y492-R495 PolarHBondContact O-N 3.35Å; Y492-R495 VanDerWaalsContact O-N 3.07Å; Y492-A496 HydrophobicContact CD1-CB 4.33Å; Y492-A496 HydrophobicContact CE1-CB 4.21Å; Y492-A496 VanDerWaalsContact O-CB 3.22Å; Y492-A496 WeakPolarHBondContact O-CB 3.44Å; Y492-A496 PolarHBondContact O-N 3.41Å
493G80.4Confident76.6Confident1 Ų180.7 Ų80.71%0.0135%0.354CS..Hα-helixtrans-59-40.2-179.800000113.5N489 P490 L497 L522N489-G493 PolarHBondContact O-N 2.97Å; P490-G493 PolarHBondContact O-N 2.94Å; G493-L497 VanDerWaalsContact O-CB 3.29Å; G493-L497 WeakPolarHBondContact O-CB 3.26Å; G493-L497 PolarHBondContact O-N 3.34Å; G493-L522 VanDerWaalsContact CA-CD1 3.41Å
494W80.6Confident77.3Confident141 Ų14173.7 Ų73.753%0.53432%0.322SS..Hα-helixtrans-69-36.7174.6-79.9113.8000113.4P490 Y492 L497 R498P490-W494 PolarHBondContact O-N 3.18Å; Y492-W494 VanDerWaalsContact C-N 3.32Å; Y492-W494 PolarHBondContact O-N 2.89Å; W494-L497 HydrophobicContact CE3-CD2 4.27Å; W494-L497 HydrophobicContact CZ3-CD2 4.15Å; W494-R498 WeakPolarHBondContact O-CG 3.44Å; W494-R498 PolarHBondContact O-N 3.36Å
495R80.8Confident77.5Confident154 Ų15470.6 Ų70.658%0.58132%0.322SS*.Hα-helixtrans-68.3-45.7175.2-71.7172.669.9-179.51.5111F466 N491 Y492 L497 R498 L499F466-R495 HydrophobicContact CE2-CB 4.41Å; F466-R495 HydrophobicContact CZ-CB 3.79Å; N491-R495 VanDerWaalsContact O-CG 3.28Å; N491-R495 WeakPolarHBondContact O-CG 3.27Å; N491-R495 PolarHBondContact O-N 3.01Å; Y492-R495 PolarHBondContact O-N 3.35Å; Y492-R495 VanDerWaalsContact O-N 3.07Å; R495-L497 PolarHBondContact O-N 3.45Å; R495-R498 PolarHBondContact O-N 3.45Å; R495-L499 PolarHBondContact O-N 2.89Å
496A82.8Confident77.2Confident0 Ų070.7 Ų70.70%032%0.323CS..Hα-helixtrans-55.5-49.9174.600000111.6F466 F467 Y492 R498 L499 L500 L522F466-A496 HydrophobicContact CE1-CB 3.91Å; F467-A496 HydrophobicContact CE1-CB 3.65Å; F467-A496 HydrophobicContact CZ-CB 3.56Å; Y492-A496 HydrophobicContact CD1-CB 4.33Å; Y492-A496 HydrophobicContact CE1-CB 4.21Å; Y492-A496 VanDerWaalsContact O-CB 3.22Å; Y492-A496 WeakPolarHBondContact O-CB 3.44Å; Y492-A496 PolarHBondContact O-N 3.41Å; A496-R498 PolarHBondContact O-N 3.35Å; A496-L499 PolarHBondContact O-N 3.26Å; A496-L500 WeakPolarHBondContact O-CB 3.36Å; A496-L500 VanDerWaalsContact O-CG 3.26Å; A496-L500 WeakPolarHBondContact O-CG 3.32Å; A496-L500 PolarHBondContact O-N 3.48Å; A496-L522 HydrophobicContact CB-CD1 4.1Å; A496-L522 HydrophobicContact CB-CD2 3.8Å
497L81Confident77.3Confident38 Ų3871.7 Ų71.720%0.19933%0.326CS..Hα-helixtrans-61.4-42.4-179.8-168.874.8000112.3G493 W494 R495 S501 F507 L518 Y521G493-L497 VanDerWaalsContact O-CB 3.29Å; G493-L497 WeakPolarHBondContact O-CB 3.26Å; G493-L497 PolarHBondContact O-N 3.34Å; W494-L497 HydrophobicContact CE3-CD2 4.27Å; W494-L497 HydrophobicContact CZ3-CD2 4.15Å; R495-L497 PolarHBondContact O-N 3.45Å; L497-S501 WeakPolarHBondContact O-CB 3.44Å; L497-S501 PolarHBondContact O-N 3.08Å; L497-F507 HydrophobicContact CD1-CE2 3.58Å; L497-F507 HydrophobicContact CD1-CZ 3.98Å; L497-F507 HydrophobicContact CG-CE2 4.19Å; L497-F507 HydrophobicContact CG-CZ 4.31Å; L497-L518 HydrophobicContact CB-CD1 4.38Å; L497-L518 HydrophobicContact CD1-CD1 3.85Å; L497-L518 HydrophobicContact CD2-CD1 4.13Å; L497-L518 HydrophobicContact CG-CD1 4.36Å; L497-Y521 HydrophobicContact CD1-CD1 4.03Å; L497-Y521 HydrophobicContact CD1-CE1 3.66Å
498R82.4Confident77.2Confident162 Ų16279.2 Ų79.261%0.61136%0.358SS*.Hα-helixtrans-64.2-41.8176.3-71.4177.7-150.7164.86.4111.5W494 R495 A496 S501 R502W494-R498 WeakPolarHBondContact O-CG 3.44Å; W494-R498 PolarHBondContact O-N 3.36Å; R495-R498 PolarHBondContact O-N 3.45Å; A496-R498 PolarHBondContact O-N 3.35Å; R498-S501 PolarHBondContact O-N 3.41Å; R498-S501 PolarHBondContact O-OG 2.8Å; R498-R502 WeakPolarHBondContact O-CG 3.11Å; R498-R502 PolarHBondContact O-N 3.02Å
499L82.7Confident77.1Confident12 Ų1278.9 Ų78.96%0.06336%0.361CS..Hα-helixtrans-65.6-47.3178.7-170.564.8000111.2M460 P461 L463 F466 F467 R495 A496 S501 R502 R503M460-L499 HydrophobicContact CG-CD1 3.57Å; M460-L499 HydrophobicContact SD-CD1 3.97Å; P461-L499 HydrophobicContact CG-CD2 4.39Å; L463-L499 HydrophobicContact CD2-CD2 3.99Å; L463-L499 HydrophobicContact CD2-CG 3.82Å; F466-L499 HydrophobicContact CB-CD2 3.63Å; F466-L499 HydrophobicContact CD1-CD2 3.71Å; F466-L499 HydrophobicContact CG-CD2 3.68Å; F467-L499 HydrophobicContact CE2-CD2 4.29Å; R495-L499 PolarHBondContact O-N 2.89Å; A496-L499 PolarHBondContact O-N 3.26Å; L499-S501 VanDerWaalsContact C-N 3.33Å; L499-S501 PolarHBondContact O-N 2.83Å; L499-R502 PolarHBondContact O-N 3.36Å; L499-R502 VanDerWaalsContact O-N 3.15Å; L499-R503 HydrophobicContact CD1-CG 4.45Å; L499-R503 PolarHBondContact O-N 3.03Å
500L80.3Confident76.1Confident1 Ų181.3 Ų81.31%0.00538%0.382CS..Hα-helixtrans-58.3-43.3176.4-69.7170000111.8L463 F467 A496 R502 S504 F507 L522 M525 L529L463-L500 HydrophobicContact CD2-CD2 4.04Å; F467-L500 HydrophobicContact CE2-CD2 3.78Å; F467-L500 HydrophobicContact CE2-CG 3.93Å; F467-L500 HydrophobicContact CZ-CD1 3.85Å; F467-L500 HydrophobicContact CZ-CD2 3.93Å; F467-L500 HydrophobicContact CZ-CG 3.7Å; A496-L500 WeakPolarHBondContact O-CB 3.36Å; A496-L500 VanDerWaalsContact O-CG 3.26Å; A496-L500 WeakPolarHBondContact O-CG 3.32Å; A496-L500 PolarHBondContact O-N 3.48Å; L500-R502 PolarHBondContact O-N 2.64Å; L500-R502 VanDerWaalsContact O-N 3.14Å; L500-S504 WeakPolarHBondContact O-CA 3.45Å; L500-S504 WeakPolarHBondContact O-CB 3.32Å; L500-S504 PolarHBondContact O-N 3.09Å; L500-F507 HydrophobicContact CB-CD2 3.84Å; L500-F507 HydrophobicContact CB-CE2 4.31Å; L500-L522 HydrophobicContact CD1-CD2 3.53Å; L500-M525 HydrophobicContact CD1-CB 4.3Å; L500-L529 HydrophobicContact CD2-CD1 3.71Å
501S79.9Confident75.4Confident40 Ų4079.9 Ų79.928%0.2837%0.371SS..Hα-helixtrans-61.4-23.8-18072.80000114.5L497 R498 L499L497-S501 WeakPolarHBondContact O-CB 3.44Å; L497-S501 PolarHBondContact O-N 3.08Å; R498-S501 PolarHBondContact O-N 3.41Å; R498-S501 PolarHBondContact O-OG 2.8Å; L499-S501 VanDerWaalsContact C-N 3.33Å; L499-S501 PolarHBondContact O-N 2.83Å
502R77.6Confident74.4Confident191 Ų19182.4 Ų82.472%0.72139%0.385SS*.Hα-helixtrans-101.9-34-175.6-62.9-177.787.2143.54.5113.2R498 L499 L500R498-R502 WeakPolarHBondContact O-CG 3.11Å; R498-R502 PolarHBondContact O-N 3.02Å; L499-R502 PolarHBondContact O-N 3.36Å; L499-R502 VanDerWaalsContact O-N 3.15Å; L500-R502 PolarHBondContact O-N 2.64Å; L500-R502 VanDerWaalsContact O-N 3.14Å
503R75.7Confident73.5Confident132 Ų13286.9 Ų86.950%0.49841%0.407SS..Hα-helixtrans-110.3-24.3-173.9-68.8-74.5-168.8154.11.4113.5E458 M460 L463 L499 P505E458-R503 IonicContact OE2-NH2 3.42Å; M460-R503 HydrophobicContact SD-CG 4.07Å; L463-R503 HydrophobicContact CD1-CB 3.8Å; L463-R503 HydrophobicContact CD2-CB 4.25Å; L463-R503 HydrophobicContact CG-CB 3.92Å; L499-R503 HydrophobicContact CD1-CG 4.45Å; L499-R503 PolarHBondContact O-N 3.03Å; R503-P505 WeakPolarHBondContact O-CD 3.42Å
504S73.6Confident72.5Confident8 Ų896.5 Ų96.56%0.05645%0.448CS..  trans-87.3119.8-178.5-175.30000111L500 H506 F507L500-S504 WeakPolarHBondContact O-CA 3.45Å; L500-S504 WeakPolarHBondContact O-CB 3.32Å; L500-S504 PolarHBondContact O-N 3.09Å; S504-H506 PolarHBondContact O-N 3.02Å; S504-H506 PolarHBondContact OG-N 3.28Å; S504-F507 PolarHBondContact O-N 3.07Å
505P68Low71.8Confident101 Ų10192.9 Ų92.966%0.65644%0.436SS*.THydrogen-bonded Turntrans-67.6-15173.627.7-32.6000112.5R503R503-P505 WeakPolarHBondContact O-CD 3.42Å
506H65.8Low71Confident47 Ų4795.3 Ų95.322%0.21845%0.451CS..THydrogen-bonded Turntrans-87.2-8.3-178.6-60-68.8000113.8S504 F508 Q509 E532S504-H506 PolarHBondContact O-N 3.02Å; S504-H506 PolarHBondContact OG-N 3.28Å; H506-F508 PolarHBondContact O-N 3.46Å; H506-Q509 PolarHBondContact ND1-NE2 2.96Å; H506-Q509 VanDerWaalsContact ND1-NE2 3.2Å; H506-Q509 PolarHBondContact ND1-OE1 3.22Å; H506-Q509 PolarHBondContact O-N 3.04Å; H506-E532 IonicContact CD2-OE2 3.5Å; H506-E532 IonicContact CE1-OE1 3.73Å; H506-E532 IonicContact NE2-OE1 3.67Å; H506-E532 PolarHBondContact NE2-OE1 3.04Å; H506-E532 IonicContact NE2-OE2 2.87Å; H506-E532 PolarHBondContact NE2-OE2 3.38Å
507F72.6Confident70.6Confident47 Ų4797.7 Ų97.721%0.20647%0.468CS..THydrogen-bonded Turntrans-65.6-40.3-176.5-170.7-94.3000113.3L497 L500 S504 Y521L497-F507 HydrophobicContact CD1-CE2 3.58Å; L497-F507 HydrophobicContact CD1-CZ 3.98Å; L497-F507 HydrophobicContact CG-CE2 4.19Å; L497-F507 HydrophobicContact CG-CZ 4.31Å; L500-F507 HydrophobicContact CB-CD2 3.84Å; L500-F507 HydrophobicContact CB-CE2 4.31Å; S504-F507 PolarHBondContact O-N 3.07Å; F507-Y521 WeakPolarHBondContact CD2-OH 3.25Å; F507-Y521 HydrophobicContact CE2-CE1 4.17Å; F507-Y521 WeakPolarHBondContact CE2-OH 3.45Å
508F70Confident70.4Confident164 Ų16498.6 Ų98.672%0.71947%0.473SS*.THydrogen-bonded Turntrans-9510.4-178.4-65.5-72.2000113.8H506H506-F508 PolarHBondContact O-N 3.46Å
509Q69.3Low70Confident101 Ų10191.6 Ų91.647%0.47245%0.449SS..SBendtrans-72.4130.9177.1-70.8-175.5-9.300110.2H506 T511H506-Q509 PolarHBondContact ND1-NE2 2.96Å; H506-Q509 VanDerWaalsContact ND1-NE2 3.2Å; H506-Q509 PolarHBondContact ND1-OE1 3.22Å; H506-Q509 PolarHBondContact O-N 3.04Å; Q509-T511 PolarHBondContact O-N 3.28Å; Q509-T511 PolarHBondContact O-OG1 2.87Å; Q509-T511 VanDerWaalsContact O-OG1 3.08Å
510P58.9Low69.7Low132 Ų13294.3 Ų94.386%0.85746%0.464SS*.  trans-60.199.4178.8-18.729.6000110
511T60.1Low69.6Low60 Ų6095.5 Ų95.537%0.36847%0.468SS..  trans-92.7118.5177.1-10.50000107.7Q509 Q513Q509-T511 PolarHBondContact O-N 3.28Å; Q509-T511 PolarHBondContact O-OG1 2.87Å; Q509-T511 VanDerWaalsContact O-OG1 3.08Å; T511-Q513 PolarHBondContact O-N 3.24Å
512N57.8Low69.4Low175 Ų17593.6 Ų93.694%0.93646%0.455SS*.SBendtrans-68.93.8174.6-87.9-31.9000113.5
513Q62.5Low69.3Low117 Ų11786.3 Ų86.355%0.54743%0.43SS..  trans-92.9120175.4-80.6178.3-16.600110.7T511 F515T511-Q513 PolarHBondContact O-N 3.24Å; Q513-F515 HydrophobicContact CB-CE2 4.38Å; Q513-F515 HydrophobicContact CB-CZ 4.16Å; Q513-F515 PolarHBondContact O-N 3.44Å
514K61.3Low69.3Low204 Ų20482.3 Ų82.389%0.88742%0.421SS*.  trans-80.4105.7167.3-66.8-176.6-179.3-179.30108.5
515F63.8Low69.3Low65 Ų6582.3 Ų82.329%0.28542%0.42SS..  trans-69.9136173.7-59.2-80.8000110Q513 Y521 T524Q513-F515 HydrophobicContact CB-CE2 4.38Å; Q513-F515 HydrophobicContact CB-CZ 4.16Å; Q513-F515 PolarHBondContact O-N 3.44Å; F515-Y521 AromaticContact CD1-CD2 3.98Å; F515-Y521 HydrophobicContact CD1-CD2 3.98Å; F515-Y521 HydrophobicContact CD1-CG 4.46Å; F515-Y521 AromaticContact CD2-CD2 3.51Å; F515-Y521 HydrophobicContact CD2-CD2 3.51Å; F515-Y521 HydrophobicContact CD2-CE2 4.21Å; F515-Y521 HydrophobicContact CD2-CG 4.37Å; F515-Y521 AromaticContact CE1-CD2 3.89Å; F515-Y521 HydrophobicContact CE1-CD2 3.89Å; F515-Y521 AromaticContact CE2-CD2 3.43Å; F515-Y521 HydrophobicContact CE2-CD2 3.43Å; F515-Y521 VanDerWaalsContact CE2-CD2 3.43Å; F515-Y521 AromaticContact CE2-CE2 3.83Å; F515-Y521 HydrophobicContact CE2-CE2 3.83Å; F515-Y521 AromaticContact CG-CD2 3.8Å; F515-Y521 HydrophobicContact CG-CD2 3.8Å; F515-Y521 HydrophobicContact CG-CG 4.31Å; F515-Y521 AromaticContact CZ-CD2 3.63Å; F515-Y521 HydrophobicContact CZ-CD2 3.63Å; F515-Y521 HydrophobicContact CZ-CE2 4.16Å; F515-T524 HydrophobicContact CE1-CG2 4.46Å
516K65.1Low69.6Low204 Ų20477.5 Ų77.589%0.88739%0.389SS*.SBendtrans-87-34.8180-68.4-178-178.4175.90112.1
517S75.1Confident70Confident51 Ų5178.1 Ų78.136%0.35740%0.398SS..SBendtrans-135.9158.4176.680.20000111.9A519 D520 Y521S517-A519 VanDerWaalsContact C-N 3.27Å; S517-A519 PolarHBondContact O-N 2.81Å; S517-D520 WeakPolarHBondContact CB-OD2 2.97Å; S517-D520 PolarHBondContact N-OD2 3.31Å; S517-D520 PolarHBondContact O-N 2.76Å; S517-D520 PolarHBondContact OG-N 2.95Å; S517-D520 PolarHBondContact OG-OD1 3.09Å; S517-D520 PolarHBondContact OG-OD2 3.36Å; S517-Y521 PolarHBondContact O-N 3.35Å
518L75.8Confident70Confident57 Ų5779.9 Ų79.930%0.29841%0.405SS..Hα-helixtrans-63.1-34.4176.4177.760.6000111.8L497 Y521 L522L497-L518 HydrophobicContact CB-CD1 4.38Å; L497-L518 HydrophobicContact CD1-CD1 3.85Å; L497-L518 HydrophobicContact CD2-CD1 4.13Å; L497-L518 HydrophobicContact CG-CD1 4.36Å; L518-Y521 HydrophobicContact CD1-CD1 4.41Å; L518-Y521 PolarHBondContact O-N 3Å; L518-L522 HydrophobicContact CD1-CD1 4.12Å; L518-L522 HydrophobicContact CD1-CG 4.15Å; L518-L522 HydrophobicContact CG-CD1 3.96Å; L518-L522 HydrophobicContact CG-CG 4.42Å; L518-L522 WeakPolarHBondContact O-CB 2.97Å; L518-L522 VanDerWaalsContact O-CG 3.3Å; L518-L522 WeakPolarHBondContact O-CG 3.44Å; L518-L522 PolarHBondContact O-N 3.45Å
519A74.7Confident70.1Confident14 Ų1473 Ų7312%0.11638%0.376CS..Hα-helixtrans-64.6-44.9178.300000111.5V487 R488 S517 Y521 L522 D523V487-A519 HydrophobicContact CG1-CB 4.29Å; V487-A519 WeakPolarHBondContact CG1-O 3.39Å; R488-A519 HydrophobicContact CG-CB 3.82Å; S517-A519 VanDerWaalsContact C-N 3.27Å; S517-A519 PolarHBondContact O-N 2.81Å; A519-Y521 VanDerWaalsContact C-N 3.27Å; A519-Y521 PolarHBondContact O-N 3.38Å; A519-L522 PolarHBondContact O-N 2.78Å; A519-D523 PolarHBondContact O-N 3.33Å
520D76.4Confident70Confident70 Ų7070.3 Ų70.337%0.37437%0.371SS..Hα-helixtrans-62.9-36.2178.7-53.1-37.7000112.2S517 T524S517-D520 WeakPolarHBondContact CB-OD2 2.97Å; S517-D520 PolarHBondContact N-OD2 3.31Å; S517-D520 PolarHBondContact O-N 2.76Å; S517-D520 PolarHBondContact OG-N 2.95Å; S517-D520 PolarHBondContact OG-OD1 3.09Å; S517-D520 PolarHBondContact OG-OD2 3.36Å; D520-T524 PolarHBondContact O-N 3.04Å; D520-T524 PolarHBondContact O-OG1 2.9Å
521Y77.7Confident70.6Confident25 Ų2572.5 Ų72.510%0.09837%0.367CS..Hα-helixtrans-65.2-47.8175.2173.6-106.6000111.5L497 F507 F515 S517 L518 A519 T524 M525L497-Y521 HydrophobicContact CD1-CD1 4.03Å; L497-Y521 HydrophobicContact CD1-CE1 3.66Å; F507-Y521 WeakPolarHBondContact CD2-OH 3.25Å; F507-Y521 HydrophobicContact CE2-CE1 4.17Å; F507-Y521 WeakPolarHBondContact CE2-OH 3.45Å; F515-Y521 AromaticContact CD1-CD2 3.98Å; F515-Y521 HydrophobicContact CD1-CD2 3.98Å; F515-Y521 HydrophobicContact CD1-CG 4.46Å; F515-Y521 AromaticContact CD2-CD2 3.51Å; F515-Y521 HydrophobicContact CD2-CD2 3.51Å; F515-Y521 HydrophobicContact CD2-CE2 4.21Å; F515-Y521 HydrophobicContact CD2-CG 4.37Å; F515-Y521 AromaticContact CE1-CD2 3.89Å; F515-Y521 HydrophobicContact CE1-CD2 3.89Å; F515-Y521 AromaticContact CE2-CD2 3.43Å; F515-Y521 HydrophobicContact CE2-CD2 3.43Å; F515-Y521 VanDerWaalsContact CE2-CD2 3.43Å; F515-Y521 AromaticContact CE2-CE2 3.83Å; F515-Y521 HydrophobicContact CE2-CE2 3.83Å; F515-Y521 AromaticContact CG-CD2 3.8Å; F515-Y521 HydrophobicContact CG-CD2 3.8Å; F515-Y521 HydrophobicContact CG-CG 4.31Å; F515-Y521 AromaticContact CZ-CD2 3.63Å; F515-Y521 HydrophobicContact CZ-CD2 3.63Å; F515-Y521 HydrophobicContact CZ-CE2 4.16Å; S517-Y521 PolarHBondContact O-N 3.35Å; L518-Y521 HydrophobicContact CD1-CD1 4.41Å; L518-Y521 PolarHBondContact O-N 3Å; A519-Y521 VanDerWaalsContact C-N 3.27Å; A519-Y521 PolarHBondContact O-N 3.38Å; Y521-T524 PolarHBondContact O-N 3.44Å; Y521-M525 HydrophobicContact CD2-CG 4.37Å; Y521-M525 HydrophobicContact CE1-CG 4.08Å; Y521-M525 HydrophobicContact CE2-CE 3.51Å; Y521-M525 HydrophobicContact CE2-CG 3.94Å; Y521-M525 WeakPolarHBondContact O-CG 3.39Å; Y521-M525 PolarHBondContact O-N 3.13Å; Y521-M525 WeakPolarHBondContact OH-CE 3.3Å
522L75.7Confident70.8Confident0 Ų075.2 Ų75.20%038%0.375CS..Hα-helixtrans-67.3-40.6-179.2-72.7174.6000111.8V487 G493 A496 L500 L518 A519 T524 M525 V526V487-L522 HydrophobicContact CG1-CB 3.35Å; V487-L522 HydrophobicContact CG1-CD1 4.2Å; V487-L522 HydrophobicContact CG1-CG 4.42Å; G493-L522 VanDerWaalsContact CA-CD1 3.41Å; A496-L522 HydrophobicContact CB-CD1 4.1Å; A496-L522 HydrophobicContact CB-CD2 3.8Å; L500-L522 HydrophobicContact CD1-CD2 3.53Å; L518-L522 HydrophobicContact CD1-CD1 4.12Å; L518-L522 HydrophobicContact CD1-CG 4.15Å; L518-L522 HydrophobicContact CG-CD1 3.96Å; L518-L522 HydrophobicContact CG-CG 4.42Å; L518-L522 WeakPolarHBondContact O-CB 2.97Å; L518-L522 VanDerWaalsContact O-CG 3.3Å; L518-L522 WeakPolarHBondContact O-CG 3.44Å; L518-L522 PolarHBondContact O-N 3.45Å; A519-L522 PolarHBondContact O-N 2.78Å; L522-T524 VanDerWaalsContact C-N 3.3Å; L522-T524 PolarHBondContact O-N 3.32Å; L522-M525 PolarHBondContact O-N 2.59Å; L522-M525 VanDerWaalsContact O-N 3.13Å; L522-V526 WeakPolarHBondContact O-CB 3.29Å; L522-V526 WeakPolarHBondContact O-CG2 3.47Å; L522-V526 PolarHBondContact O-N 2.85Å
523D76.5Confident70.9Confident38 Ų3869.8 Ų69.820%0.20335%0.346CS..Hα-helixtrans-58-44.2173.8-83.8-19.5000111.2A519 M525 V526 C527A519-D523 PolarHBondContact O-N 3.33Å; D523-M525 VanDerWaalsContact C-N 3.33Å; D523-M525 PolarHBondContact O-N 3.23Å; D523-V526 PolarHBondContact O-N 3.04Å; D523-C527 WeakPolarHBondContact O-CB 3.45Å; D523-C527 PolarHBondContact O-N 3Å; D523-C527 PolarHBondContact O-SG 3.09Å
524T75.4Confident70Confident49 Ų4969.8 Ų69.830%0.30136%0.357SS..Hα-helixtrans-64.2-38.5177.4-54.70000112F515 D520 Y521 L522 K528F515-T524 HydrophobicContact CE1-CG2 4.46Å; D520-T524 PolarHBondContact O-N 3.04Å; D520-T524 PolarHBondContact O-OG1 2.9Å; Y521-T524 PolarHBondContact O-N 3.44Å; L522-T524 VanDerWaalsContact C-N 3.3Å; L522-T524 PolarHBondContact O-N 3.32Å; T524-K528 WeakPolarHBondContact O-CG 3.46Å; T524-K528 PolarHBondContact O-N 3.29Å
525M72.6Confident69.4Low7 Ų769.5 Ų69.53%0.03436%0.355CS..Hα-helixtrans-74.5-39.6179-75.2-59.6-179.800112.4L500 Y521 L522 D523 C527 K528 L529L500-M525 HydrophobicContact CD1-CB 4.3Å; Y521-M525 HydrophobicContact CD2-CG 4.37Å; Y521-M525 HydrophobicContact CE1-CG 4.08Å; Y521-M525 HydrophobicContact CE2-CE 3.51Å; Y521-M525 HydrophobicContact CE2-CG 3.94Å; Y521-M525 WeakPolarHBondContact O-CG 3.39Å; Y521-M525 PolarHBondContact O-N 3.13Å; Y521-M525 WeakPolarHBondContact OH-CE 3.3Å; L522-M525 PolarHBondContact O-N 2.59Å; L522-M525 VanDerWaalsContact O-N 3.13Å; D523-M525 VanDerWaalsContact C-N 3.33Å; D523-M525 PolarHBondContact O-N 3.23Å; M525-C527 VanDerWaalsContact C-N 3.32Å; M525-C527 PolarHBondContact O-N 3.36Å; M525-K528 PolarHBondContact O-N 3.3Å; M525-K528 VanDerWaalsContact O-N 3.11Å; M525-K528 HydrophobicContact SD-CD 4.11Å; M525-L529 WeakPolarHBondContact O-CG 3.37Å; M525-L529 PolarHBondContact O-N 3.37Å
526V75.5Confident68Low0 Ų074 Ų740%038%0.382CS..Hα-helixtrans-59.7-43.4172.91690000110.3F467 A470 I471 A474 L522 D523 K528 L529 A530F467-V526 HydrophobicContact CD1-CG2 3.65Å; F467-V526 HydrophobicContact CE1-CG2 4.01Å; A470-V526 HydrophobicContact CB-CG1 4.31Å; A470-V526 HydrophobicContact CB-CG2 4.16Å; I471-V526 HydrophobicContact CB-CG1 4.37Å; I471-V526 HydrophobicContact CG1-CG1 3.68Å; A474-V526 HydrophobicContact CB-CG1 4.16Å; L522-V526 WeakPolarHBondContact O-CB 3.29Å; L522-V526 WeakPolarHBondContact O-CG2 3.47Å; L522-V526 PolarHBondContact O-N 2.85Å; D523-V526 PolarHBondContact O-N 3.04Å; V526-K528 VanDerWaalsContact C-N 3.27Å; V526-K528 PolarHBondContact O-N 3.44Å; V526-L529 PolarHBondContact O-N 3.05Å; V526-A530 VanDerWaalsContact O-CB 3.29Å; V526-A530 WeakPolarHBondContact O-CB 3.46Å; V526-A530 PolarHBondContact O-N 3.04Å
527C72.8Confident66.4Low60 Ų6072 Ų7241%0.40538%0.38SS..Hα-helixtrans-64.3-27.7175.2-70.60000114D523 M525 K531D523-C527 WeakPolarHBondContact O-CB 3.45Å; D523-C527 PolarHBondContact O-N 3Å; D523-C527 PolarHBondContact O-SG 3.09Å; M525-C527 VanDerWaalsContact C-N 3.32Å; M525-C527 PolarHBondContact O-N 3.36Å; C527-K531 WeakPolarHBondContact O-CG 3.47Å
528K73.4Confident64.3Low85 Ų8575.1 Ų75.137%0.3740%0.399SS..Hα-helixtrans-79.6-45.3175.7-74.5174.1-177.4176.80111T524 M525 V526 A530 K531 E532T524-K528 WeakPolarHBondContact O-CG 3.46Å; T524-K528 PolarHBondContact O-N 3.29Å; M525-K528 PolarHBondContact O-N 3.3Å; M525-K528 VanDerWaalsContact O-N 3.11Å; M525-K528 HydrophobicContact SD-CD 4.11Å; V526-K528 VanDerWaalsContact C-N 3.27Å; V526-K528 PolarHBondContact O-N 3.44Å; K528-A530 VanDerWaalsContact C-N 3.33Å; K528-A530 PolarHBondContact O-N 3.4Å; K528-K531 WeakPolarHBondContact O-CB 3.42Å; K528-K531 PolarHBondContact O-N 2.84Å; K528-K531 VanDerWaalsContact O-N 3.07Å; K528-E532 PolarHBondContact O-N 2.99Å
529L72.3Confident62.2Low18 Ų1877.9 Ų77.99%0.09442%0.422CS..Hα-helixtrans-59.4-43.9175.5-71168.6000111.3L463 F467 L500 M525 V526 K531 E532 L533L463-L529 HydrophobicContact CD1-CD2 4.44Å; F467-L529 HydrophobicContact CD2-CD1 4.14Å; F467-L529 HydrophobicContact CE2-CD1 4.38Å; F467-L529 HydrophobicContact CG-CD1 4.49Å; L500-L529 HydrophobicContact CD2-CD1 3.71Å; M525-L529 WeakPolarHBondContact O-CG 3.37Å; M525-L529 PolarHBondContact O-N 3.37Å; V526-L529 PolarHBondContact O-N 3.05Å; L529-K531 PolarHBondContact O-N 3.02Å; L529-K531 VanDerWaalsContact O-N 3.08Å; L529-E532 PolarHBondContact O-N 3.33Å; L529-L533 VanDerWaalsContact O-CD1 3.23Å; L529-L533 WeakPolarHBondContact O-CD1 3.47Å; L529-L533 PolarHBondContact O-N 3.05Å
530A67.5Low60Low45 Ų4586.6 Ų86.637%0.37246%0.461SS..Hα-helixtrans-59.5-21.6175.900000114.3I471 V526 K528I471-A530 HydrophobicContact CG1-CB 4.26Å; I471-A530 HydrophobicContact CG2-CB 3.76Å; V526-A530 VanDerWaalsContact O-CB 3.29Å; V526-A530 WeakPolarHBondContact O-CB 3.46Å; V526-A530 PolarHBondContact O-N 3.04Å; K528-A530 VanDerWaalsContact C-N 3.33Å; K528-A530 PolarHBondContact O-N 3.4Å
531K70.3Confident57.8Low179 Ų17992.3 Ų92.378%0.77849%0.485SS*.Hα-helixtrans-89.3-18.9176.5-71.1173.9-176.4177.30113.3C527 K528 L529C527-K531 WeakPolarHBondContact O-CG 3.47Å; K528-K531 WeakPolarHBondContact O-CB 3.42Å; K528-K531 PolarHBondContact O-N 2.84Å; K528-K531 VanDerWaalsContact O-N 3.07Å; L529-K531 PolarHBondContact O-N 3.02Å; L529-K531 VanDerWaalsContact O-N 3.08Å
532E65.1Low55.5Low116 Ų11699 Ų9954%0.54252%0.521SS..Hα-helixtrans-96.7-17.9-177.5-71.9-176.2167.700113.1H506 K528 L529H506-E532 IonicContact CD2-OE2 3.5Å; H506-E532 IonicContact CE1-OE1 3.73Å; H506-E532 IonicContact NE2-OE1 3.67Å; H506-E532 PolarHBondContact NE2-OE1 3.04Å; H506-E532 IonicContact NE2-OE2 2.87Å; H506-E532 PolarHBondContact NE2-OE2 3.38Å; K528-E532 PolarHBondContact O-N 2.99Å; L529-E532 PolarHBondContact O-N 3.33Å
533L58.8Low53.2Low61 Ų61108.5 Ų108.532%0.31956%0.562SS.*SBendtrans-68.3135.5171.8-91.490.4000111.8D464 L529 K535D464-L533 HydrophobicContact CB-CD2 3.96Å; D464-L533 WeakPolarHBondContact OD1-CD1 3.43Å; L529-L533 VanDerWaalsContact O-CD1 3.23Å; L529-L533 WeakPolarHBondContact O-CD1 3.47Å; L529-L533 PolarHBondContact O-N 3.05Å; L533-K535 PolarHBondContact O-N 3.35Å
534P45.2Very low51Low118 Ų118112.7 Ų112.777%0.76659%0.59SS**  trans-61.7124.8163.9-15.128.6000109.7D536P534-D536 PolarHBondContact O-N 3.38Å
535K48.5Very low48.8Very low198 Ų198114.1 Ų114.186%0.86161%0.614SS**SBendtrans-68.599.9168-71.7-177.9177.5-174.90108.2L533L533-K535 PolarHBondContact O-N 3.35Å
536D34Very low46.6Very low158 Ų158122.3 Ų122.385%0.84565%0.652SS**  trans-178.490.3151.4-87.5-27.4000110.5P534P534-D536 PolarHBondContact O-N 3.38Å
537I31Very low44.3Very low164 Ų164130 Ų13084%0.84169%0.688SS**  trans-140.6127.8144.5-54.9-179.5000107
538P30.7Very low42.1Very low116 Ų116133.6 Ų133.675%0.75370%0.703SS**  trans-72138177.3-6.623.2000111E540P538-E540 PolarHBondContact O-N 2.94Å
539S32.4Very low39.9Very low114 Ų114136.3 Ų136.380%0.79772%0.721SS**  trans-45.6124.9163.346.30000113
540E29.3Very low37.8Very low197 Ų197142.6 Ų142.692%0.92176%0.755SS**  trans-122132.4153.9-86.5-159.5161.100111.1P538P538-E540 PolarHBondContact O-N 2.94Å
541E29.2Very low35.9Very low191 Ų191146.8 Ų146.889%0.89377%0.771SS**  trans-73.2141.6-168-61.9170.8143.600112.2K543E541-K543 PolarHBondContact O-N 3.49Å
542I29.5Very low33.9Very low164 Ų164145.5 Ų145.584%0.84177%0.773SS**  trans-62.8119.8167.2-64.5160.7000108.8
543K26.9Very low32.1Very low200 Ų200143.6 Ų143.687%0.8779%0.785SS**  trans-116.4111.7161.5-148.6174.4-172.3175.90109.9E541E541-K543 PolarHBondContact O-N 3.49Å
544T31.1Very low30.6Very low127 Ų127147.1 Ų147.178%0.77980%0.804SS**  trans-56.9143.817448.80000113.3
545G27.9Very low29.7Very low78 Ų78147.4 Ų147.480%0.80480%0.799SS**  trans-174.4131.5165.700000111.6
546E27.6Very low28.7Very low179 Ų179145 Ų14584%0.83680%0.795SS**  trans-80.5158.3-162.1-68.8161.1153.800116
547E27.9Very low28.4Very low162 Ų162144.6 Ų144.676%0.75779%0.792SS**  trans57.3132137.1-68.9178.2176.700124
548D26Very low28.2Very low135 Ų135145.2 Ų145.272%0.72279%0.788SS**  trans82.5119135-66.8-4.2000124.1
549D27.6Very low28Very low142 Ų142146.1 Ų146.176%0.75979%0.787SS**  53.1127.8129.8-81.8-9.1000123.6
550D28.5Very low27.7Very low150 Ų150146.4 Ų146.480%0.80279%0.789SS**  trans78.3123.8135.4-88.8-9.4000123.2
551D27.6Very low27.6Very low133 Ų133145 Ų14571%0.71179%0.788SS**  trans94.6128.7131.1-143.418.4000121.3
552N27.7Very low27.4Very low153 Ų153143.2 Ų143.282%0.81878%0.784SS**  trans30.6133151.9-96.5-29.2000122
553G27.8Very low27.3Very low76 Ų76140.2 Ų140.278%0.78478%0.778SS**  trans176.180.1160.700000114.8
554D25.9Very low27.7Very low135 Ų135136.3 Ų136.372%0.72277%0.773SS**  trans-50.3159.3172.3-166.518.8000115.7
555N26.6Very low27.7Very low123 Ų123135.5 Ų135.566%0.65877%0.772SS**  trans70.8111.5161-65.2-52000120.4
556L28.1Very low28.1Very low149 Ų149139.9 Ų139.978%0.7878%0.776SS**  173.8120.599.2-130.272.9000112
557L27.4Very low28.8Very low149 Ų149139.5 Ų139.578%0.7877%0.774SS**  trans33.7131.6137.8-57.1169.9000117.9
558K26.8Very low29.9Very low176 Ų176135.6 Ų135.677%0.76577%0.765SS**  178143.257-141.8169.4-174.5-179.40110.3
559D25.9Very low31.9Very low136 Ų136135.8 Ų135.873%0.72776%0.759SS**  trans9.9126.4152.6-54.9-40.3000119.3
560S26Very low34.1Very low119 Ų119132.9 Ų132.983%0.83275%0.746SS**  176.2101.3126.9-72.80000110
561N27.1Very low36.4Very low168 Ų168125.9 Ų125.990%0.89871%0.709SS**  trans-153.894.9145.2-133.211.7000111.2
562D25.8Very low38.9Very low154 Ų154122.9 Ų122.982%0.82470%0.696SS**  trans-90.2137.8163.1-123.9-24.7000108.3
563S28.3Very low41.2Very low101 Ų101120.8 Ų120.871%0.70668%0.684SS**  trans90.9152.8159.8-49.50000119.1
564P34.2Very low43.5Very low118 Ų118123.3 Ų123.377%0.76668%0.676SS**  -135.3140.8-7131.9-12.8000112.3
565S30.5Very low46Very low110 Ų110118.1 Ų118.177%0.76965%0.647SS**  trans-90.6122.6170.3410000110.8Q567S565-Q567 PolarHBondContact O-N 3.2Å
566I37.6Very low48.5Very low170 Ų170112.4 Ų112.487%0.87262%0.616SS**  trans-66.6111.2-178.4-64.2166.4000109.5
567Q42.3Very low50.8Low170 Ų170108.2 Ų108.279%0.79460%0.595SS**  trans-88.1122.4171.2-68.4176.3-4.300109.4S565 K569S565-Q567 PolarHBondContact O-N 3.2Å; Q567-K569 PolarHBondContact O-N 3.3Å
568S50.1Low53.3Low81 Ų81104.5 Ų104.557%0.56658%0.576SS**  trans-72.5115.2170.946.70000110
569K68.6Low55.9Low138 Ų13896.6 Ų96.660%0.654%0.542SS*.PPolyproline II helixtrans-80.4139.1-175.1-65.2175.8-177.1170.30111.3Q567 V632Q567-K569 PolarHBondContact O-N 3.3Å; K569-V632 HydrophobicContact CB-CG2 4.36Å; K569-V632 WeakPolarHBondContact O-CG2 3.18Å; K569-V632 PolarHBondContact O-N 3.21Å; K569-V632 VanDerWaalsContact O-N 3.16Å
570T73.8Confident58.6Low81 Ų8190.3 Ų90.350%0.49751%0.509SS..BIsolated β-bridgetrans-75.6147.9168.4520000110.8T572T570-T572 PolarHBondContact O-N 2.93Å
571V75.9Confident61.2Low3 Ų387.8 Ų87.82%0.01850%0.495CS..PPolyproline II helixtrans-64.3126.4178.9-173.60000110.6Q575 M576 W622 Q623 A630 V632 L635V571-Q575 HydrophobicContact CG1-CB 4.1Å; V571-M576 HydrophobicContact CG1-CG 3.66Å; V571-W622 HydrophobicContact CG2-CH2 4.49Å; V571-W622 HydrophobicContact CG2-CZ3 4.22Å; V571-Q623 PolarHBondContact O-NE2 3.27Å; V571-A630 PolarHBondContact N-O 2.84Å; V571-V632 HydrophobicContact CG2-CG2 4.07Å; V571-L635 HydrophobicContact CG1-CD2 3.9Å; V571-L635 HydrophobicContact CG2-CB 4.14Å; V571-L635 HydrophobicContact CG2-CD2 3.87Å
572T80.5Confident63.6Low70 Ų7084.8 Ų84.843%0.42947%0.474SS..PPolyproline II helixtrans-86.1156.5178.760.50000112.2T570 H574 Q575 M576T570-T572 PolarHBondContact O-N 2.93Å; T572-H574 PolarHBondContact O-N 3.4Å; T572-Q575 WeakPolarHBondContact O-CB 3.41Å; T572-Q575 PolarHBondContact O-N 3.3Å; T572-Q575 VanDerWaalsContact O-N 3.08Å; T572-Q575 VanDerWaalsContact OG1-CD 3.27Å; T572-Q575 VanDerWaalsContact OG1-CG 3.29Å; T572-Q575 WeakPolarHBondContact OG1-CG 3.2Å; T572-Q575 PolarHBondContact OG1-N 3.49Å; T572-Q575 PolarHBondContact OG1-OE1 3.48Å; T572-M576 PolarHBondContact O-N 2.93Å
573N75.2Confident66.1Low109 Ų10977.7 Ų77.758%0.58344%0.436SS*.Hα-helixtrans-57.7-34.7177.3-73.3-23.2000113.3M576 D577N573-M576 HydrophobicContact CB-CE 4.39Å; N573-M576 PolarHBondContact O-N 3.18Å; N573-M576 WeakPolarHBondContact OD1-CE 3.38Å; N573-D577 VanDerWaalsContact O-CG 3.31Å; N573-D577 PolarHBondContact O-N 3.26Å
574H77.1Confident68.3Low129 Ų12973.5 Ų73.560%0.59741%0.409SS*.Hα-helixtrans-67.4-40.7176.2-170.9-69.3000111.9T572 M576 D577 D578T572-H574 PolarHBondContact O-N 3.4Å; H574-M576 VanDerWaalsContact C-N 3.3Å; H574-M576 PolarHBondContact O-N 2.91Å; H574-D577 PolarHBondContact O-N 3.19Å; H574-D578 IonicContact CE1-OD1 3.77Å; H574-D578 IonicContact CE1-OD2 3.55Å; H574-D578 PolarHBondContact CE1-OD2 2.88Å; H574-D578 IonicContact ND1-OD2 3.56Å; H574-D578 PolarHBondContact ND1-OD2 2.88Å; H574-D578 PolarHBondContact O-N 2.99Å
575Q78.8Confident70.3Confident27 Ų2772.3 Ų72.313%0.12640%0.403CS..Hα-helixtrans-64.5-36.8175.4-73.1166.7-38.700111.3V571 T572 I579 L651 A654V571-Q575 HydrophobicContact CG1-CB 4.1Å; T572-Q575 WeakPolarHBondContact O-CB 3.41Å; T572-Q575 PolarHBondContact O-N 3.3Å; T572-Q575 VanDerWaalsContact O-N 3.08Å; T572-Q575 VanDerWaalsContact OG1-CD 3.27Å; T572-Q575 VanDerWaalsContact OG1-CG 3.29Å; T572-Q575 WeakPolarHBondContact OG1-CG 3.2Å; T572-Q575 PolarHBondContact OG1-N 3.49Å; T572-Q575 PolarHBondContact OG1-OE1 3.48Å; Q575-I579 WeakPolarHBondContact O-CB 3.48Å; Q575-I579 WeakPolarHBondContact O-CD1 3.17Å; Q575-I579 WeakPolarHBondContact O-CG1 3.42Å; Q575-I579 PolarHBondContact O-N 2.94Å; Q575-L651 HydrophobicContact CB-CD1 4.12Å; Q575-L651 HydrophobicContact CG-CD1 4.24Å; Q575-A654 PolarHBondContact NE2-OXT 2.88Å
576M79Confident72.6Confident2 Ų272 Ų721%0.0139%0.39CS..Hα-helixtrans-66-39.5174.4-66.9-170.3-72.900112.4V571 T572 N573 H574 I579 A580 L619 Q623V571-M576 HydrophobicContact CG1-CG 3.66Å; T572-M576 PolarHBondContact O-N 2.93Å; N573-M576 HydrophobicContact CB-CE 4.39Å; N573-M576 PolarHBondContact O-N 3.18Å; N573-M576 WeakPolarHBondContact OD1-CE 3.38Å; H574-M576 VanDerWaalsContact C-N 3.3Å; H574-M576 PolarHBondContact O-N 2.91Å; M576-I579 PolarHBondContact O-N 2.91Å; M576-A580 VanDerWaalsContact O-CB 3.22Å; M576-A580 WeakPolarHBondContact O-CB 3.29Å; M576-A580 PolarHBondContact O-N 2.91Å; M576-L619 HydrophobicContact CB-CB 4.28Å; M576-L619 HydrophobicContact CB-CD1 4.04Å; M576-L619 HydrophobicContact CG-CB 4.11Å; M576-L619 HydrophobicContact CG-CD1 4.34Å; M576-L619 WeakPolarHBondContact O-CD1 3.48Å; M576-L619 HydrophobicContact SD-CB 3.89Å; M576-Q623 VanDerWaalsContact CE-OE1 3.28Å
577D77Confident74.8Confident62 Ų6264 Ų6433%0.33235%0.349SS..Hα-helixtrans-65.7-42177.6-71.9-10.2000111.8N573 H574 I579 A580 A581 K616N573-D577 VanDerWaalsContact O-CG 3.31Å; N573-D577 PolarHBondContact O-N 3.26Å; H574-D577 PolarHBondContact O-N 3.19Å; D577-I579 VanDerWaalsContact C-N 3.33Å; D577-I579 PolarHBondContact O-N 3.47Å; D577-A580 PolarHBondContact O-N 3.06Å; D577-A581 WeakPolarHBondContact O-CB 3.38Å; D577-A581 PolarHBondContact O-N 2.98Å; D577-K616 WeakPolarHBondContact OD1-CD 3.41Å; D577-K616 WeakPolarHBondContact OD1-CE 3.44Å; D577-K616 IonicContact OD1-NZ 3.77Å; D577-K616 PolarHBondContact OD1-NZ 3.01Å; D577-K616 IonicContact OD2-NZ 2.63Å; D577-K616 PolarHBondContact OD2-NZ 3.06Å
578D79.6Confident76.6Confident71 Ų7160.7 Ų60.738%0.3833%0.332SS..Hα-helixtrans-67.4-31.6177-77.8-31.6000113.5H574 K582H574-D578 IonicContact CE1-OD1 3.77Å; H574-D578 IonicContact CE1-OD2 3.55Å; H574-D578 PolarHBondContact CE1-OD2 2.88Å; H574-D578 IonicContact ND1-OD2 3.56Å; H574-D578 PolarHBondContact ND1-OD2 2.88Å; H574-D578 PolarHBondContact O-N 2.99Å; D578-K582 WeakPolarHBondContact O-CG 3.35Å
579I80.9Confident78.2Confident9 Ų959.9 Ų59.95%0.04632%0.323CS..Hα-helixtrans-76.5-46.3174.7-67.1164.1000109.5Q575 M576 D577 A581 K582 L583 L619 L635 L639 L651Q575-I579 WeakPolarHBondContact O-CB 3.48Å; Q575-I579 WeakPolarHBondContact O-CD1 3.17Å; Q575-I579 WeakPolarHBondContact O-CG1 3.42Å; Q575-I579 PolarHBondContact O-N 2.94Å; M576-I579 PolarHBondContact O-N 2.91Å; D577-I579 VanDerWaalsContact C-N 3.33Å; D577-I579 PolarHBondContact O-N 3.47Å; I579-A581 VanDerWaalsContact C-N 3.32Å; I579-A581 PolarHBondContact O-N 3.47Å; I579-K582 CarbonylContact O-C 3.59Å; I579-K582 PolarHBondContact O-N 2.85Å; I579-L583 VanDerWaalsContact O-CB 3.24Å; I579-L583 WeakPolarHBondContact O-CB 3.31Å; I579-L583 PolarHBondContact O-N 3.27Å; I579-L619 HydrophobicContact CB-CD1 4.02Å; I579-L619 HydrophobicContact CG2-CD1 3.89Å; I579-L635 HydrophobicContact CD1-CD2 3.75Å; I579-L639 HydrophobicContact CD1-CD1 4.26Å; I579-L639 HydrophobicContact CG2-CD1 4.49Å; I579-L639 HydrophobicContact CG2-CD2 4.37Å; I579-L651 HydrophobicContact CD1-CD1 3.93Å; I579-L651 HydrophobicContact CD1-CD2 3.83Å; I579-L651 HydrophobicContact CD1-CG 4.35Å
580A81.9Confident78.9Confident4 Ų453.3 Ų53.33%0.03330%0.295CS..Hα-helixtrans-56.2-46.4179.900000111.6M576 D577 K582 L583 G584 A615 K616 L619M576-A580 VanDerWaalsContact O-CB 3.22Å; M576-A580 WeakPolarHBondContact O-CB 3.29Å; M576-A580 PolarHBondContact O-N 2.91Å; D577-A580 PolarHBondContact O-N 3.06Å; A580-K582 PolarHBondContact O-N 2.89Å; A580-L583 PolarHBondContact O-N 3.38Å; A580-G584 PolarHBondContact O-N 3.41Å; A580-G584 VanDerWaalsContact O-N 3.16Å; A580-A615 HydrophobicContact CB-CB 3.97Å; A580-K616 HydrophobicContact CB-CB 3.87Å; A580-L619 HydrophobicContact CB-CD1 4.48Å
581A80Confident79.3Confident66 Ų6649.5 Ų49.555%0.54527%0.271SS..Hα-helixtrans-63.3-21.6177.900000114.3D577 I579D577-A581 WeakPolarHBondContact O-CB 3.38Å; D577-A581 PolarHBondContact O-N 2.98Å; I579-A581 VanDerWaalsContact C-N 3.32Å; I579-A581 PolarHBondContact O-N 3.47Å
582K79.3Confident79.5Confident106 Ų10652.8 Ų52.846%0.46130%0.295SS..Hα-helixtrans-101.6-24.8179-67.2176.5-171.2126.90113.1D578 I579 A580 L647D578-K582 WeakPolarHBondContact O-CG 3.35Å; I579-K582 CarbonylContact O-C 3.59Å; I579-K582 PolarHBondContact O-N 2.85Å; A580-K582 PolarHBondContact O-N 2.89Å; K582-L647 HydrophobicContact CB-CD1 4.18Å; K582-L647 HydrophobicContact CB-CD2 3.72Å; K582-L647 HydrophobicContact CD-CD2 3.47Å; K582-L647 VanDerWaalsContact CD-CD2 3.47Å; K582-L647 HydrophobicContact CG-CD2 4.24Å
583L78.3Confident79.5Confident4 Ų453.7 Ų53.72%0.02129%0.294CS..Hα-helixtrans-74.4-38.7178.8-163.374.5000110.7I579 A580 S585 Q586 W587 L590 A615 L639 F644I579-L583 VanDerWaalsContact O-CB 3.24Å; I579-L583 WeakPolarHBondContact O-CB 3.31Å; I579-L583 PolarHBondContact O-N 3.27Å; A580-L583 PolarHBondContact O-N 3.38Å; L583-S585 PolarHBondContact O-N 2.78Å; L583-Q586 PolarHBondContact O-N 2.99Å; L583-Q586 VanDerWaalsContact O-N 3.08Å; L583-W587 HydrophobicContact CD2-CB 3.7Å; L583-W587 HydrophobicContact CG-CB 4.26Å; L583-L590 HydrophobicContact CD1-CB 4.26Å; L583-L590 HydrophobicContact CD1-CD2 4Å; L583-L590 HydrophobicContact CD2-CB 4.16Å; L583-L590 HydrophobicContact CD2-CD2 3.55Å; L583-L590 HydrophobicContact CG-CD2 4.46Å; L583-A615 HydrophobicContact CB-CB 4.38Å; L583-A615 HydrophobicContact CD2-CB 4.21Å; L583-L639 HydrophobicContact CD1-CD2 4.24Å; L583-F644 HydrophobicContact CD1-CD2 4.04Å; L583-F644 HydrophobicContact CD1-CE1 4.32Å; L583-F644 HydrophobicContact CD1-CE2 3.82Å; L583-F644 HydrophobicContact CD1-CG 4.41Å; L583-F644 HydrophobicContact CD1-CZ 3.99Å
584G74.8Confident79.8Confident13 Ų1348.9 Ų48.913%0.13427%0.268CS..G310 helixtrans45.6-130.7175.600000112.2A580 Q586 W587 V611A580-G584 PolarHBondContact O-N 3.41Å; A580-G584 VanDerWaalsContact O-N 3.16Å; G584-Q586 PolarHBondContact O-N 3.32Å; G584-W587 VanDerWaalsContact O-CD1 3.29Å; G584-W587 PolarHBondContact O-N 2.9Å; G584-V611 WeakPolarHBondContact O-CG1 3.31Å
585S74.6Confident79.9Confident94 Ų9450.4 Ų50.466%0.65728%0.275SS*.G310 helixtrans-69-6.8-174.158.90000115.1L583 W587L583-S585 PolarHBondContact O-N 2.78Å; S585-W587 VanDerWaalsContact C-N 3.34Å
586Q79.6Confident79.9Confident104 Ų10449.8 Ų49.849%0.48627%0.273SS..G310 helixtrans-94.610.7-178.7-51.5-167.6-1100113.1L583 G584 K588 T589 L590 F644L583-Q586 PolarHBondContact O-N 2.99Å; L583-Q586 VanDerWaalsContact O-N 3.08Å; G584-Q586 PolarHBondContact O-N 3.32Å; Q586-K588 PolarHBondContact O-N 3.1Å; Q586-T589 WeakPolarHBondContact O-CB 3.34Å; Q586-T589 PolarHBondContact O-N 3.23Å; Q586-L590 PolarHBondContact O-N 2.73Å; Q586-F644 HydrophobicContact CB-CE1 4.21Å; Q586-F644 HydrophobicContact CB-CZ 3.64Å; Q586-F644 VanDerWaalsContact OE1-CZ 3.23Å
587W83.1Confident80.1Confident2 Ų256.4 Ų56.41%0.00830%0.301CS..Hα-helixtrans-57.2-30.1176.471.9-103.6000113.5L583 G584 S585 T589 L590 A591 M601 I604 E605 Q614 A615 L618L583-W587 HydrophobicContact CD2-CB 3.7Å; L583-W587 HydrophobicContact CG-CB 4.26Å; G584-W587 VanDerWaalsContact O-CD1 3.29Å; G584-W587 PolarHBondContact O-N 2.9Å; S585-W587 VanDerWaalsContact C-N 3.34Å; W587-T589 VanDerWaalsContact C-N 3.31Å; W587-T589 PolarHBondContact O-N 3.01Å; W587-L590 PolarHBondContact O-N 3.08Å; W587-A591 HydrophobicContact CE3-CB 4.31Å; W587-A591 HydrophobicContact CZ3-CB 4.43Å; W587-A591 WeakPolarHBondContact O-CB 3.33Å; W587-A591 PolarHBondContact O-N 3.06Å; W587-M601 HydrophobicContact CZ3-CB 4.43Å; W587-M601 HydrophobicContact CZ3-CG 4.4Å; W587-I604 HydrophobicContact CH2-CB 4.18Å; W587-I604 HydrophobicContact CH2-CG2 3.88Å; W587-I604 HydrophobicContact CZ2-CG2 4.23Å; W587-I604 HydrophobicContact CZ3-CG2 4.22Å; W587-E605 HydrophobicContact CH2-CG 4.02Å; W587-E605 HydrophobicContact CZ2-CG 3.85Å; W587-Q614 HydrophobicContact CD2-CB 4.42Å; W587-Q614 HydrophobicContact CZ2-CB 4.05Å; W587-Q614 HydrophobicContact CZ2-CG 4.38Å; W587-A615 HydrophobicContact CB-CB 3.86Å; W587-A615 HydrophobicContact CG-CB 4.44Å; W587-L618 HydrophobicContact CB-CD2 4.25Å; W587-L618 HydrophobicContact CE3-CB 4.37Å; W587-L618 HydrophobicContact CE3-CD1 3.86Å; W587-L618 HydrophobicContact CE3-CD2 4.14Å; W587-L618 HydrophobicContact CE3-CG 4.36Å; W587-L618 HydrophobicContact CZ3-CD1 3.98Å; W587-L618 WeakPolarHBondContact O-CD2 3.38Å
588K81.6Confident80.1Confident100 Ų10056.4 Ų56.444%0.43531%0.31SS..Hα-helixtrans-64.5-34.1176.5-62.9-179.7-178.7-174.30113.2Q586 A591 S592 E605Q586-K588 PolarHBondContact O-N 3.1Å; K588-A591 PolarHBondContact O-N 3.09Å; K588-S592 PolarHBondContact O-N 3.01Å; K588-E605 WeakPolarHBondContact CE-OE1 3.39Å; K588-E605 IonicContact NZ-OE1 3.04Å; K588-E605 PolarHBondContact NZ-OE1 2.81Å
589T82.1Confident80.1Confident64 Ų6455.8 Ų55.839%0.39332%0.315SS..Hα-helixtrans-65.7-46.6175.4-50.60000109.2Q586 W587 A591 S592 H593Q586-T589 WeakPolarHBondContact O-CB 3.34Å; Q586-T589 PolarHBondContact O-N 3.23Å; W587-T589 VanDerWaalsContact C-N 3.31Å; W587-T589 PolarHBondContact O-N 3.01Å; T589-A591 PolarHBondContact O-N 3.36Å; T589-S592 PolarHBondContact O-N 3.43Å; T589-S592 PolarHBondContact O-OG 3.47Å; T589-H593 PolarHBondContact O-CD2 3.16Å; T589-H593 VanDerWaalsContact O-CD2 3.27Å; T589-H593 PolarHBondContact O-N 3.06Å
590L83.4Confident80Confident0 Ų057.9 Ų57.90%032%0.324CS..Hα-helixtrans-63.4-40.9175.8-173.862.6000112.2L583 Q586 W587 S592 H593 L594 L618 L619 A638 L639 A642L583-L590 HydrophobicContact CD1-CB 4.26Å; L583-L590 HydrophobicContact CD1-CD2 4Å; L583-L590 HydrophobicContact CD2-CB 4.16Å; L583-L590 HydrophobicContact CD2-CD2 3.55Å; L583-L590 HydrophobicContact CG-CD2 4.46Å; Q586-L590 PolarHBondContact O-N 2.73Å; W587-L590 PolarHBondContact O-N 3.08Å; L590-S592 PolarHBondContact O-N 3.31Å; L590-H593 CarbonylContact O-C 3.21Å; L590-H593 PolarHBondContact O-N 3.35Å; L590-L594 HydrophobicContact CD1-CD1 4.35Å; L590-L594 HydrophobicContact CD1-CG 4.24Å; L590-L594 HydrophobicContact CD2-CD1 4.12Å; L590-L594 HydrophobicContact CG-CD1 3.75Å; L590-L594 HydrophobicContact CG-CG 4.09Å; L590-L594 WeakPolarHBondContact O-CG 3.34Å; L590-L594 PolarHBondContact O-N 3.31Å; L590-L618 HydrophobicContact CB-CD2 4.36Å; L590-L618 HydrophobicContact CD2-CD2 4.43Å; L590-L618 HydrophobicContact CG-CD2 4.48Å; L590-L619 HydrophobicContact CD2-CD2 4.15Å; L590-A638 HydrophobicContact CD1-CB 4.4Å; L590-L639 HydrophobicContact CD1-CD2 3.82Å; L590-L639 HydrophobicContact CD1-CG 4.18Å; L590-L639 HydrophobicContact CD2-CD2 3.75Å; L590-L639 HydrophobicContact CG-CD2 4.41Å; L590-A642 HydrophobicContact CD1-CB 4.03Å
591A82.4Confident79.9Confident0 Ų059.8 Ų59.80%033%0.333CS..Hα-helixtrans-55.7-38.2178.200000112.8W587 K588 T589 L594 E595 M596 M601 L618W587-A591 HydrophobicContact CE3-CB 4.31Å; W587-A591 HydrophobicContact CZ3-CB 4.43Å; W587-A591 WeakPolarHBondContact O-CB 3.33Å; W587-A591 PolarHBondContact O-N 3.06Å; K588-A591 PolarHBondContact O-N 3.09Å; T589-A591 PolarHBondContact O-N 3.36Å; A591-L594 PolarHBondContact O-N 3.19Å; A591-E595 PolarHBondContact O-N 3.38Å; A591-M596 HydrophobicContact CB-CB 4.44Å; A591-M596 PolarHBondContact O-N 3.1Å; A591-M601 HydrophobicContact CB-CG 4.05Å; A591-M601 HydrophobicContact CB-SD 3.59Å; A591-M601 VanDerWaalsContact CB-SD 3.59Å; A591-L618 HydrophobicContact CB-CD1 3.44Å; A591-L618 VanDerWaalsContact CB-CD1 3.44Å; A591-L618 HydrophobicContact CB-CD2 4Å; A591-L618 HydrophobicContact CB-CG 4.35Å
592S80.2Confident79.9Confident73 Ų7364.2 Ų64.251%0.5134%0.335SS..Hα-helixtrans-67.9-34.3176.974.20000113K588 T589 L590 E595K588-S592 PolarHBondContact O-N 3.01Å; T589-S592 PolarHBondContact O-N 3.43Å; T589-S592 PolarHBondContact O-OG 3.47Å; L590-S592 PolarHBondContact O-N 3.31Å; S592-E595 PolarHBondContact O-N 3.43Å
593H81.6Confident80.1Confident88 Ų8864.9 Ų64.941%0.40734%0.34SS..Hα-helixtrans-82.1-22.3176.8-74.1-74.1000113.3T589 L590 E595 A641 A642T589-H593 PolarHBondContact O-CD2 3.16Å; T589-H593 VanDerWaalsContact O-CD2 3.27Å; T589-H593 PolarHBondContact O-N 3.06Å; L590-H593 CarbonylContact O-C 3.21Å; L590-H593 PolarHBondContact O-N 3.35Å; H593-E595 PolarHBondContact O-N 3.18Å; H593-A641 PolarHBondContact CE1-O 3.04Å; H593-A642 HydrophobicContact CB-CB 4.29Å; H593-A642 VanDerWaalsContact CD2-CA 3.48Å; H593-A642 WeakPolarHBondContact CD2-CA 3.45Å; H593-A642 VanDerWaalsContact CD2-CB 3.47Å; H593-A642 WeakPolarHBondContact CD2-CB 3.44Å
594L81.1Confident80.3Confident8 Ų865.3 Ų65.34%0.04234%0.342CS..THydrogen-bonded Turntrans-84.310.7169.1-64.2175.2000112.3L590 A591 M596 L618 W622 R625 L635 A638L590-L594 HydrophobicContact CD1-CD1 4.35Å; L590-L594 HydrophobicContact CD1-CG 4.24Å; L590-L594 HydrophobicContact CD2-CD1 4.12Å; L590-L594 HydrophobicContact CG-CD1 3.75Å; L590-L594 HydrophobicContact CG-CG 4.09Å; L590-L594 WeakPolarHBondContact O-CG 3.34Å; L590-L594 PolarHBondContact O-N 3.31Å; A591-L594 PolarHBondContact O-N 3.19Å; L594-M596 HydrophobicContact CB-CG 4.21Å; L594-M596 PolarHBondContact O-N 3.28Å; L594-M596 VanDerWaalsContact O-N 3.17Å; L594-L618 HydrophobicContact CD1-CD2 4.41Å; L594-W622 HydrophobicContact CD1-CB 4.26Å; L594-W622 HydrophobicContact CD1-CG 4.05Å; L594-W622 HydrophobicContact CD2-CD2 4.31Å; L594-W622 HydrophobicContact CD2-CG 4.22Å; L594-R625 PolarHBondContact O-NH1 2.89Å; L594-R625 PolarHBondContact O-NH2 3.21Å; L594-L635 HydrophobicContact CD2-CD1 4.42Å; L594-A638 HydrophobicContact CD2-CB 3.41Å; L594-A638 VanDerWaalsContact CD2-CB 3.41Å; L594-A638 HydrophobicContact CG-CB 4.32Å
595E79.2Confident80.5Confident161 Ų16168.4 Ų68.475%0.75235%0.353SS*.THydrogen-bonded Turntrans5236.9179.8-57.3-171.9167.400113.6A591 S592 H593 R625A591-E595 PolarHBondContact O-N 3.38Å; S592-E595 PolarHBondContact O-N 3.43Å; H593-E595 PolarHBondContact O-N 3.18Å; E595-R625 PolarHBondContact O-NH1 3.26Å
596M79.2Confident80.8Confident15 Ų1569.6 Ų69.67%0.07436%0.357CS..  trans-77.4141177.8-67.2-163.659.900111.7A591 L594 E600 M601 I604 L618 A621A591-M596 HydrophobicContact CB-CB 4.44Å; A591-M596 PolarHBondContact O-N 3.1Å; L594-M596 HydrophobicContact CB-CG 4.21Å; L594-M596 PolarHBondContact O-N 3.28Å; L594-M596 VanDerWaalsContact O-N 3.17Å; M596-E600 HydrophobicContact CE-CB 4.09Å; M596-M601 HydrophobicContact CB-CG 4.47Å; M596-I604 HydrophobicContact CE-CD1 4.01Å; M596-L618 HydrophobicContact CE-CD1 3.86Å; M596-L618 HydrophobicContact CG-CD1 4.45Å; M596-L618 HydrophobicContact SD-CD1 3.14Å; M596-L618 WeakPolarHBondContact SD-CD1 3.28Å; M596-L618 HydrophobicContact SD-CG 3.79Å; M596-A621 HydrophobicContact CE-CB 3.82Å
597K81.6Confident80.7Confident141 Ų14169.8 Ų69.861%0.61336%0.361SS*.  trans-71.3148.3-176.7-68175.7-173.7157.80110.4A599 E600 M601K597-A599 PolarHBondContact O-N 2.88Å; K597-E600 HydrophobicContact CB-CG 4.29Å; K597-E600 PolarHBondContact N-OE2 3.01Å; K597-E600 VanDerWaalsContact N-OE2 3.1Å; K597-E600 PolarHBondContact O-N 3.1Å; K597-M601 PolarHBondContact O-N 3.44Å; K597-M601 VanDerWaalsContact O-N 3.12Å
598A77.3Confident80.3Confident61 Ų6170.8 Ų70.850%0.50437%0.368SS..Hα-helixtrans-63.2-12.8175.200000114.7M601 R602A598-M601 HydrophobicContact CB-CE 4.14Å; A598-R602 WeakPolarHBondContact O-CG 3.5Å; A598-R602 PolarHBondContact O-NE 3.2Å
599A79.7Confident79.8Confident59 Ų5975.5 Ų75.549%0.48839%0.392SS..Hα-helixtrans-78-47169.800000111.4K597 M601 R602 E603K597-A599 PolarHBondContact O-N 2.88Å; A599-M601 VanDerWaalsContact C-N 3.34Å; A599-M601 PolarHBondContact O-N 2.87Å; A599-R602 PolarHBondContact O-N 3.34Å; A599-R602 VanDerWaalsContact O-N 3.11Å; A599-E603 PolarHBondContact O-N 3.43Å
600E79.4Confident79.7Confident52 Ų5276.6 Ų76.624%0.24340%0.395CS..Hα-helixtrans-63.1-39.7179.3-65.7158.8-167.400111.2M596 K597 R602 E603 I604M596-E600 HydrophobicContact CE-CB 4.09Å; K597-E600 HydrophobicContact CB-CG 4.29Å; K597-E600 PolarHBondContact N-OE2 3.01Å; K597-E600 VanDerWaalsContact N-OE2 3.1Å; K597-E600 PolarHBondContact O-N 3.1Å; E600-R602 VanDerWaalsContact C-N 3.31Å; E600-R602 PolarHBondContact O-N 3.36Å; E600-E603 PolarHBondContact O-N 3.06Å; E600-I604 VanDerWaalsContact O-CG1 3.32Å; E600-I604 WeakPolarHBondContact O-CG1 3.44Å; E600-I604 PolarHBondContact O-N 2.65Å
601M78.8Confident79.5Confident44 Ų4479 Ų7922%0.21741%0.41CS..Hα-helixtrans-63.6-34174.6-65-170.8-69.100113W587 A591 M596 K597 A598 A599 E605W587-M601 HydrophobicContact CZ3-CB 4.43Å; W587-M601 HydrophobicContact CZ3-CG 4.4Å; A591-M601 HydrophobicContact CB-CG 4.05Å; A591-M601 HydrophobicContact CB-SD 3.59Å; A591-M601 VanDerWaalsContact CB-SD 3.59Å; M596-M601 HydrophobicContact CB-CG 4.47Å; K597-M601 PolarHBondContact O-N 3.44Å; K597-M601 VanDerWaalsContact O-N 3.12Å; A598-M601 HydrophobicContact CB-CE 4.14Å; A599-M601 VanDerWaalsContact C-N 3.34Å; A599-M601 PolarHBondContact O-N 2.87Å; M601-E605 WeakPolarHBondContact O-CG 3.19Å; M601-E605 PolarHBondContact O-N 3.08Å
602R80.9Confident79.1Confident159 Ų15982.7 Ų82.760%0.643%0.43SS*.Hα-helixtrans-76.4-30.5177.7-78.6-174.4-72174.10.9112.6A598 A599 E600 T606A598-R602 WeakPolarHBondContact O-CG 3.5Å; A598-R602 PolarHBondContact O-NE 3.2Å; A599-R602 PolarHBondContact O-N 3.34Å; A599-R602 VanDerWaalsContact O-N 3.11Å; E600-R602 VanDerWaalsContact C-N 3.31Å; E600-R602 PolarHBondContact O-N 3.36Å; R602-T606 PolarHBondContact O-N 3.37Å; R602-T606 PolarHBondContact O-OG1 3.22Å
603E82.6Confident79.1Confident121 Ų12182 Ų8257%0.56542%0.423SS*.Hα-helixtrans-66.7-49.2173.7-168.7168.2-166.100110.1A599 E600 E605 T606 D607A599-E603 PolarHBondContact O-N 3.43Å; E600-E603 PolarHBondContact O-N 3.06Å; E603-E605 VanDerWaalsContact C-N 3.27Å; E603-E605 PolarHBondContact O-N 2.84Å; E603-T606 PolarHBondContact O-N 3.25Å; E603-D607 VanDerWaalsContact O-CG 3.32Å; E603-D607 PolarHBondContact O-N 3.39Å
604I82.4Confident79.2Confident12 Ų1278.9 Ų78.96%0.06241%0.408CS..Hα-helixtrans-58.7-36.8175.4-64.9165.2000112.1W587 M596 E600 T606 Q614 L617 L618W587-I604 HydrophobicContact CH2-CB 4.18Å; W587-I604 HydrophobicContact CH2-CG2 3.88Å; W587-I604 HydrophobicContact CZ2-CG2 4.23Å; W587-I604 HydrophobicContact CZ3-CG2 4.22Å; M596-I604 HydrophobicContact CE-CD1 4.01Å; E600-I604 VanDerWaalsContact O-CG1 3.32Å; E600-I604 WeakPolarHBondContact O-CG1 3.44Å; E600-I604 PolarHBondContact O-N 2.65Å; I604-T606 VanDerWaalsContact C-N 3.33Å; I604-Q614 HydrophobicContact CG2-CB 3.97Å; I604-Q614 HydrophobicContact CG2-CG 4.21Å; I604-L617 HydrophobicContact CG1-CB 4.4Å; I604-L617 HydrophobicContact CG2-CB 4.02Å; I604-L618 HydrophobicContact CD1-CB 4.43Å; I604-L618 HydrophobicContact CD1-CD1 4.04Å
605E80.2Confident79.3Confident78 Ų7878.5 Ų78.536%0.36441%0.406SS..Hα-helixtrans-66.6-31.4174.1-79.6176.817600113.8W587 K588 M601 E603W587-E605 HydrophobicContact CH2-CG 4.02Å; W587-E605 HydrophobicContact CZ2-CG 3.85Å; K588-E605 WeakPolarHBondContact CE-OE1 3.39Å; K588-E605 IonicContact NZ-OE1 3.04Å; K588-E605 PolarHBondContact NZ-OE1 2.81Å; M601-E605 WeakPolarHBondContact O-CG 3.19Å; M601-E605 PolarHBondContact O-N 3.08Å; E603-E605 VanDerWaalsContact C-N 3.27Å; E603-E605 PolarHBondContact O-N 2.84Å
606T80.3Confident79.6Confident119 Ų11974.9 Ų74.973%0.7339%0.388SS*.Hα-helixtrans-83.4-29.2-178.3-52.30000111.2R602 E603 I604R602-T606 PolarHBondContact O-N 3.37Å; R602-T606 PolarHBondContact O-OG1 3.22Å; E603-T606 PolarHBondContact O-N 3.25Å; I604-T606 VanDerWaalsContact C-N 3.33Å
607D77.8Confident79.7Confident108 Ų10877 Ų7758%0.57840%0.4SS*.Hα-helixtrans-76.6-21.7-174.3-75-11.8000114.3E603 L617E603-D607 VanDerWaalsContact O-CG 3.32Å; E603-D607 PolarHBondContact O-N 3.39Å; D607-L617 HydrophobicContact CB-CD1 4.35Å
608S75Confident79.9Confident23 Ų2370.3 Ų70.316%0.16137%0.37CS..  trans-153.7138.8177.7179.40000112.3D610 Q614S608-D610 PolarHBondContact OG-N 3.04Å; S608-D610 VanDerWaalsContact OG-N 3.09Å; S608-D610 PolarHBondContact OG-O 3.39Å; S608-Q614 PolarHBondContact O-NE2 3.36Å
609E71.3Confident80.3Confident200 Ų20067.4 Ų67.494%0.93535%0.346SS*.SBendtrans-82.7-15.5169.5-64.2-175.3173.700112.6
610D78.8Confident80.5Confident86 Ų8666.6 Ų66.646%0.4634%0.335SS..  trans-83.7122.4178.6-168.9-22.6000111S608 D612 V613 Q614S608-D610 PolarHBondContact OG-N 3.04Å; S608-D610 VanDerWaalsContact OG-N 3.09Å; S608-D610 PolarHBondContact OG-O 3.39Å; D610-D612 PolarHBondContact O-N 2.93Å; D610-D612 PolarHBondContact OD1-N 3.06Å; D610-V613 HydrophobicContact CB-CB 4.11Å; D610-V613 HydrophobicContact CB-CG2 3.83Å; D610-V613 PolarHBondContact O-N 3.42Å; D610-Q614 WeakPolarHBondContact O-CG 3.49Å; D610-Q614 PolarHBondContact O-N 2.75Å
611V78.9Confident80.7Confident52 Ų5265.8 Ų65.832%0.31534%0.337SS..Hα-helixtrans-67.2-34.1-174178.80000112.3G584 V613 Q614 A615G584-V611 WeakPolarHBondContact O-CG1 3.31Å; V611-V613 VanDerWaalsContact C-N 3.35Å; V611-Q614 PolarHBondContact O-N 3.2Å; V611-A615 PolarHBondContact O-N 3.25Å; V611-A615 VanDerWaalsContact O-N 3.08Å
612D75.3Confident81.1Confident76 Ų7664.2 Ų64.241%0.40633%0.329SS..Hα-helixtrans-74.4-33.4179.5-66.8-22.1000110.5D610 A615 K616D610-D612 PolarHBondContact O-N 2.93Å; D610-D612 PolarHBondContact OD1-N 3.06Å; D612-A615 PolarHBondContact O-N 3.17Å; D612-K616 PolarHBondContact O-N 2.84Å; D612-K616 VanDerWaalsContact O-N 3.09Å
613V80.6Confident81.2Confident60 Ų6059.1 Ų59.136%0.36431%0.312SS..Hα-helixtrans-69.4-39.6173.5-179.70000110.8D610 V611 A615 K616 L617D610-V613 HydrophobicContact CB-CB 4.11Å; D610-V613 HydrophobicContact CB-CG2 3.83Å; D610-V613 PolarHBondContact O-N 3.42Å; V611-V613 VanDerWaalsContact C-N 3.35Å; V613-A615 PolarHBondContact O-N 3.31Å; V613-K616 PolarHBondContact O-N 3.24Å; V613-L617 HydrophobicContact CG1-CD1 4.09Å; V613-L617 HydrophobicContact CG1-CG 4.37Å; V613-L617 WeakPolarHBondContact O-CB 3.45Å; V613-L617 VanDerWaalsContact O-CG 3.31Å; V613-L617 WeakPolarHBondContact O-CG 3.3Å; V613-L617 PolarHBondContact O-N 3.45Å
614Q82.9Confident81.1Confident22 Ų2260.9 Ų60.910%0.10332%0.32CS..Hα-helixtrans-60.9-42.9173.8-70.9175.1-9.700112W587 I604 S608 D610 V611 K616 L617 L618W587-Q614 HydrophobicContact CD2-CB 4.42Å; W587-Q614 HydrophobicContact CZ2-CB 4.05Å; W587-Q614 HydrophobicContact CZ2-CG 4.38Å; I604-Q614 HydrophobicContact CG2-CB 3.97Å; I604-Q614 HydrophobicContact CG2-CG 4.21Å; S608-Q614 PolarHBondContact O-NE2 3.36Å; D610-Q614 WeakPolarHBondContact O-CG 3.49Å; D610-Q614 PolarHBondContact O-N 2.75Å; V611-Q614 PolarHBondContact O-N 3.2Å; Q614-K616 VanDerWaalsContact C-N 3.32Å; Q614-K616 PolarHBondContact O-N 2.91Å; Q614-L617 PolarHBondContact O-N 3.09Å; Q614-L618 PolarHBondContact O-N 3.22Å
615A84Confident81Confident0 Ų065 Ų650%034%0.335CS..Hα-helixtrans-63.4-37.7176.700000112.3A580 L583 W587 V611 D612 V613 L618 L619A580-A615 HydrophobicContact CB-CB 3.97Å; L583-A615 HydrophobicContact CB-CB 4.38Å; L583-A615 HydrophobicContact CD2-CB 4.21Å; W587-A615 HydrophobicContact CB-CB 3.86Å; W587-A615 HydrophobicContact CG-CB 4.44Å; V611-A615 PolarHBondContact O-N 3.25Å; V611-A615 VanDerWaalsContact O-N 3.08Å; D612-A615 PolarHBondContact O-N 3.17Å; V613-A615 PolarHBondContact O-N 3.31Å; A615-L618 WeakPolarHBondContact O-CB 3.48Å; A615-L619 WeakPolarHBondContact O-CG 3.23Å; A615-L619 PolarHBondContact O-N 2.81Å
616K84.3Confident80.9Confident84 Ų8464.5 Ų64.537%0.36533%0.332SS..Hα-helixtrans-68.9-44.5174.7-176.7174.9177.8156.50112.2D577 A580 D612 V613 Q614 L618 L619 V620D577-K616 WeakPolarHBondContact OD1-CD 3.41Å; D577-K616 WeakPolarHBondContact OD1-CE 3.44Å; D577-K616 IonicContact OD1-NZ 3.77Å; D577-K616 PolarHBondContact OD1-NZ 3.01Å; D577-K616 IonicContact OD2-NZ 2.63Å; D577-K616 PolarHBondContact OD2-NZ 3.06Å; A580-K616 HydrophobicContact CB-CB 3.87Å; D612-K616 PolarHBondContact O-N 2.84Å; D612-K616 VanDerWaalsContact O-N 3.09Å; V613-K616 PolarHBondContact O-N 3.24Å; Q614-K616 VanDerWaalsContact C-N 3.32Å; Q614-K616 PolarHBondContact O-N 2.91Å; K616-L618 PolarHBondContact O-N 3.05Å; K616-L619 PolarHBondContact O-N 3.47Å; K616-L619 VanDerWaalsContact O-N 3.14Å; K616-V620 HydrophobicContact CG-CG2 4.47Å; K616-V620 WeakPolarHBondContact O-CG2 3.43Å; K616-V620 PolarHBondContact O-N 2.9Å
617L82.8Confident80.6Confident61 Ų6160.9 Ų60.932%0.31932%0.319SS..Hα-helixtrans-59.8-37177.3-74.5170.9000111.7I604 D607 V613 Q614 V620 A621I604-L617 HydrophobicContact CG1-CB 4.4Å; I604-L617 HydrophobicContact CG2-CB 4.02Å; D607-L617 HydrophobicContact CB-CD1 4.35Å; V613-L617 HydrophobicContact CG1-CD1 4.09Å; V613-L617 HydrophobicContact CG1-CG 4.37Å; V613-L617 WeakPolarHBondContact O-CB 3.45Å; V613-L617 VanDerWaalsContact O-CG 3.31Å; V613-L617 WeakPolarHBondContact O-CG 3.3Å; V613-L617 PolarHBondContact O-N 3.45Å; Q614-L617 PolarHBondContact O-N 3.09Å; L617-V620 PolarHBondContact O-N 3.24Å; L617-A621 VanDerWaalsContact O-CB 3.26Å; L617-A621 WeakPolarHBondContact O-CB 3.26Å; L617-A621 PolarHBondContact O-N 2.64Å
618L85.6Confident80.1Confident0 Ų060.5 Ų60.50%033%0.325CS..Hα-helixtrans-58.8-49.6172.6-173.481.2000112.4W587 L590 A591 L594 M596 I604 Q614 A615 K616 V620 A621 W622W587-L618 HydrophobicContact CB-CD2 4.25Å; W587-L618 HydrophobicContact CE3-CB 4.37Å; W587-L618 HydrophobicContact CE3-CD1 3.86Å; W587-L618 HydrophobicContact CE3-CD2 4.14Å; W587-L618 HydrophobicContact CE3-CG 4.36Å; W587-L618 HydrophobicContact CZ3-CD1 3.98Å; W587-L618 WeakPolarHBondContact O-CD2 3.38Å; L590-L618 HydrophobicContact CB-CD2 4.36Å; L590-L618 HydrophobicContact CD2-CD2 4.43Å; L590-L618 HydrophobicContact CG-CD2 4.48Å; A591-L618 HydrophobicContact CB-CD1 3.44Å; A591-L618 VanDerWaalsContact CB-CD1 3.44Å; A591-L618 HydrophobicContact CB-CD2 4Å; A591-L618 HydrophobicContact CB-CG 4.35Å; L594-L618 HydrophobicContact CD1-CD2 4.41Å; M596-L618 HydrophobicContact CE-CD1 3.86Å; M596-L618 HydrophobicContact CG-CD1 4.45Å; M596-L618 HydrophobicContact SD-CD1 3.14Å; M596-L618 WeakPolarHBondContact SD-CD1 3.28Å; M596-L618 HydrophobicContact SD-CG 3.79Å; I604-L618 HydrophobicContact CD1-CB 4.43Å; I604-L618 HydrophobicContact CD1-CD1 4.04Å; Q614-L618 PolarHBondContact O-N 3.22Å; A615-L618 WeakPolarHBondContact O-CB 3.48Å; K616-L618 PolarHBondContact O-N 3.05Å; L618-V620 VanDerWaalsContact C-N 3.34Å; L618-A621 PolarHBondContact O-N 3.45Å; L618-W622 WeakPolarHBondContact O-CB 3.39Å; L618-W622 PolarHBondContact O-N 3.46Å
619L84Confident79.8Confident0 Ų064.9 Ų64.90%034%0.343CS..Hα-helixtrans-67.4-36.5-177.6-66.5173.8000111.9M576 I579 A580 L590 A615 K616 W622 Q623 L635M576-L619 HydrophobicContact CB-CB 4.28Å; M576-L619 HydrophobicContact CB-CD1 4.04Å; M576-L619 HydrophobicContact CG-CB 4.11Å; M576-L619 HydrophobicContact CG-CD1 4.34Å; M576-L619 WeakPolarHBondContact O-CD1 3.48Å; M576-L619 HydrophobicContact SD-CB 3.89Å; I579-L619 HydrophobicContact CB-CD1 4.02Å; I579-L619 HydrophobicContact CG2-CD1 3.89Å; A580-L619 HydrophobicContact CB-CD1 4.48Å; L590-L619 HydrophobicContact CD2-CD2 4.15Å; A615-L619 WeakPolarHBondContact O-CG 3.23Å; A615-L619 PolarHBondContact O-N 2.81Å; K616-L619 PolarHBondContact O-N 3.47Å; K616-L619 VanDerWaalsContact O-N 3.14Å; L619-W622 PolarHBondContact O-N 3.39Å; L619-Q623 WeakPolarHBondContact O-CB 3.37Å; L619-Q623 PolarHBondContact O-N 2.8Å; L619-L635 HydrophobicContact CD2-CD1 3.89Å; L619-L635 HydrophobicContact CD2-CD2 4.35Å
620V84.9Confident80Confident42 Ų4255.4 Ų55.426%0.25530%0.299SS..Hα-helixtrans-66.3-47.8174.2173.90000110.8K616 L617 L618 W622 Q623 E624K616-V620 HydrophobicContact CG-CG2 4.47Å; K616-V620 WeakPolarHBondContact O-CG2 3.43Å; K616-V620 PolarHBondContact O-N 2.9Å; L617-V620 PolarHBondContact O-N 3.24Å; L618-V620 VanDerWaalsContact C-N 3.34Å; V620-W622 VanDerWaalsContact C-N 3.27Å; V620-W622 PolarHBondContact O-N 3.33Å; V620-Q623 PolarHBondContact O-N 2.64Å; V620-Q623 VanDerWaalsContact O-N 3.13Å; V620-E624 HydrophobicContact CG1-CG 4.46Å; V620-E624 WeakPolarHBondContact O-CG 3.02Å; V620-E624 PolarHBondContact O-N 2.81Å
621A83.1Confident80.2Confident34 Ų3452.1 Ų52.128%0.28128%0.281SS..Hα-helixtrans-61.2-37.2177.300000112.1M596 L617 L618 R625M596-A621 HydrophobicContact CE-CB 3.82Å; L617-A621 VanDerWaalsContact O-CB 3.26Å; L617-A621 WeakPolarHBondContact O-CB 3.26Å; L617-A621 PolarHBondContact O-N 2.64Å; L618-A621 PolarHBondContact O-N 3.45Å; A621-R625 WeakPolarHBondContact O-CB 3.39Å; A621-R625 PolarHBondContact O-N 3.04Å; A621-R625 VanDerWaalsContact O-N 3.14Å
622W86.5Confident80.3Confident12 Ų1250.2 Ų50.25%0.04527%0.27CS..Hα-helixtrans-65.2-45.2172.617374.4000112.2V571 L594 L618 L619 V620 E624 R625 E626 A630 N634 L635V571-W622 HydrophobicContact CG2-CH2 4.49Å; V571-W622 HydrophobicContact CG2-CZ3 4.22Å; L594-W622 HydrophobicContact CD1-CB 4.26Å; L594-W622 HydrophobicContact CD1-CG 4.05Å; L594-W622 HydrophobicContact CD2-CD2 4.31Å; L594-W622 HydrophobicContact CD2-CG 4.22Å; L618-W622 WeakPolarHBondContact O-CB 3.39Å; L618-W622 PolarHBondContact O-N 3.46Å; L619-W622 PolarHBondContact O-N 3.39Å; V620-W622 VanDerWaalsContact C-N 3.27Å; V620-W622 PolarHBondContact O-N 3.33Å; W622-E624 PolarHBondContact O-N 2.99Å; W622-R625 PolarHBondContact O-N 3.14Å; W622-E626 HydrophobicContact CG-CG 4.49Å; W622-E626 HydrophobicContact CZ2-CG 4.45Å; W622-E626 PolarHBondContact O-N 2.57Å; W622-A630 HydrophobicContact CE3-CB 4.39Å; W622-A630 HydrophobicContact CH2-CB 3.82Å; W622-A630 HydrophobicContact CZ2-CB 4.38Å; W622-A630 HydrophobicContact CZ3-CB 3.82Å; W622-N634 HydrophobicContact CZ2-CB 4.43Å; W622-L635 HydrophobicContact CE3-CD1 4.37Å; W622-L635 HydrophobicContact CH2-CB 3.75Å; W622-L635 HydrophobicContact CH2-CD1 4.32Å; W622-L635 HydrophobicContact CH2-CG 4.47Å; W622-L635 HydrophobicContact CZ2-CB 4.5Å; W622-L635 HydrophobicContact CZ3-CB 4.08Å; W622-L635 HydrophobicContact CZ3-CD1 4.13Å; W622-L635 HydrophobicContact CZ3-CD2 4.22Å; W622-L635 HydrophobicContact CZ3-CG 4.37Å
623Q83.1Confident80.6Confident51 Ų5152.6 Ų52.624%0.23828%0.279CS..Hα-helixtrans-63.5-41.2178.1-175.9177.755.700112.3V571 M576 L619 V620 R625 G627 A630V571-Q623 PolarHBondContact O-NE2 3.27Å; M576-Q623 VanDerWaalsContact CE-OE1 3.28Å; L619-Q623 WeakPolarHBondContact O-CB 3.37Å; L619-Q623 PolarHBondContact O-N 2.8Å; V620-Q623 PolarHBondContact O-N 2.64Å; V620-Q623 VanDerWaalsContact O-N 3.13Å; Q623-R625 VanDerWaalsContact C-N 3.26Å; Q623-R625 PolarHBondContact O-N 2.81Å; Q623-G627 PolarHBondContact O-N 3.37Å; Q623-A630 HydrophobicContact CB-CB 4.4Å; Q623-A630 HydrophobicContact CG-CB 4.04Å
624E80.8Confident80.6Confident159 Ų15953.1 Ų53.174%0.74328%0.279SS*.Hα-helixtrans-63.4-33.3175.5-73.4-173.6166.200112.2V620 W622V620-E624 HydrophobicContact CG1-CG 4.46Å; V620-E624 WeakPolarHBondContact O-CG 3.02Å; V620-E624 PolarHBondContact O-N 2.81Å; W622-E624 PolarHBondContact O-N 2.99Å
625R81.3Confident80.5Confident97 Ų9752 Ų5237%0.36627%0.274SS..Hα-helixtrans-75.5-45.7178.7-165.9-177.175.8-173.24.1113.1L594 E595 A621 W622 Q623L594-R625 PolarHBondContact O-NH1 2.89Å; L594-R625 PolarHBondContact O-NH2 3.21Å; E595-R625 PolarHBondContact O-NH1 3.26Å; A621-R625 WeakPolarHBondContact O-CB 3.39Å; A621-R625 PolarHBondContact O-N 3.04Å; A621-R625 VanDerWaalsContact O-N 3.14Å; W622-R625 PolarHBondContact O-N 3.14Å; Q623-R625 VanDerWaalsContact C-N 3.26Å; Q623-R625 PolarHBondContact O-N 2.81Å
626E76.8Confident80.4Confident68 Ų6852.8 Ų52.832%0.31828%0.28SS..Hα-helixtrans-89-18.4-173.4-60.3-56.1145.600113.7W622 S628 Q629 A630W622-E626 HydrophobicContact CG-CG 4.49Å; W622-E626 HydrophobicContact CZ2-CG 4.45Å; W622-E626 PolarHBondContact O-N 2.57Å; E626-S628 PolarHBondContact O-N 2.84Å; E626-Q629 HydrophobicContact CB-CB 4.46Å; E626-Q629 PolarHBondContact O-N 3.01Å; E626-A630 HydrophobicContact CB-CB 4.21Å
627G74.8Confident80.4Confident43 Ų4353.2 Ų53.244%0.44329%0.29SS..G310 helixtrans56.4-119.3175.400000113.1Q623 Q629 A630Q623-G627 PolarHBondContact O-N 3.37Å; G627-Q629 PolarHBondContact O-N 3.36Å; G627-A630 WeakPolarHBondContact O-CB 3.36Å; G627-A630 PolarHBondContact O-N 3.49Å
628S66.6Low80.4Confident100 Ų10051 Ų5170%0.69928%0.28SS*.G310 helixtrans-70.6-9-179.760.20000114.4E626E626-S628 PolarHBondContact O-N 2.84Å
629Q68.5Low80.2Confident116 Ų11651 Ų5154%0.54228%0.28SS..G310 helixtrans-92.7-1174.4-61.8-64.4-38.700112.4E626 G627 T631 N634E626-Q629 HydrophobicContact CB-CB 4.46Å; E626-Q629 PolarHBondContact O-N 3.01Å; G627-Q629 PolarHBondContact O-N 3.36Å; Q629-T631 PolarHBondContact O-N 2.93Å; Q629-N634 PolarHBondContact O-ND2 3.13Å
630A76.9Confident80.1Confident1 Ų153.6 Ų53.61%0.00830%0.299CS..  trans-76.660.3172.700000111.6V571 W622 Q623 E626 G627V571-A630 PolarHBondContact N-O 2.84Å; W622-A630 HydrophobicContact CE3-CB 4.39Å; W622-A630 HydrophobicContact CH2-CB 3.82Å; W622-A630 HydrophobicContact CZ2-CB 4.38Å; W622-A630 HydrophobicContact CZ3-CB 3.82Å; Q623-A630 HydrophobicContact CB-CB 4.4Å; Q623-A630 HydrophobicContact CG-CB 4.04Å; E626-A630 HydrophobicContact CB-CB 4.21Å; G627-A630 WeakPolarHBondContact O-CB 3.36Å; G627-A630 PolarHBondContact O-N 3.49Å
631T82.8Confident80Confident16 Ų1654.7 Ų54.710%0.09831%0.312CS..BIsolated β-bridgetrans-84.1156.617962.40000111.5Q629 E633 N634 L635Q629-T631 PolarHBondContact O-N 2.93Å; T631-E633 PolarHBondContact O-N 2.89Å; T631-N634 PolarHBondContact O-N 2.88Å; T631-N634 PolarHBondContact OG1-N 3.18Å; T631-N634 PolarHBondContact OG1-ND2 3.16Å; T631-L635 PolarHBondContact O-N 3.24Å; T631-L635 VanDerWaalsContact O-N 3.13Å
632V81Confident79.8Confident13 Ų1353.7 Ų53.78%0.07930%0.304CS..Hα-helixtrans-55.6-38.3174.4175.50000111.1K569 V571 L635 A636 L651K569-V632 HydrophobicContact CB-CG2 4.36Å; K569-V632 WeakPolarHBondContact O-CG2 3.18Å; K569-V632 PolarHBondContact O-N 3.21Å; K569-V632 VanDerWaalsContact O-N 3.16Å; V571-V632 HydrophobicContact CG2-CG2 4.07Å; V632-L635 PolarHBondContact O-N 3.45Å; V632-A636 VanDerWaalsContact O-CB 3.27Å; V632-A636 WeakPolarHBondContact O-CB 3.49Å; V632-A636 PolarHBondContact O-N 2.98Å; V632-L651 HydrophobicContact CG1-CD1 4Å; V632-L651 HydrophobicContact CG1-CD2 4.42Å; V632-L651 HydrophobicContact CG1-CG 3.72Å; V632-L651 WeakPolarHBondContact CG1-O 3.42Å
633E80.5Confident79.4Confident126 Ų12655.9 Ų55.959%0.58933%0.331SS*.Hα-helixtrans-65.9-41.9178.3-66.6174.8-175.700113.1T631 A636 T637T631-E633 PolarHBondContact O-N 2.89Å; E633-A636 PolarHBondContact O-N 3.35Å; E633-T637 WeakPolarHBondContact O-CB 3.49Å; E633-T637 PolarHBondContact O-N 3.49Å; E633-T637 PolarHBondContact O-OG1 3.18Å
634N80.8Confident79.4Confident70 Ų7055 Ų5537%0.37433%0.326SS..Hα-helixtrans-68.3-40.4179-74.9-10.4000111.1W622 Q629 T631 T637 A638W622-N634 HydrophobicContact CZ2-CB 4.43Å; Q629-N634 PolarHBondContact O-ND2 3.13Å; T631-N634 PolarHBondContact O-N 2.88Å; T631-N634 PolarHBondContact OG1-N 3.18Å; T631-N634 PolarHBondContact OG1-ND2 3.16Å; N634-T637 PolarHBondContact O-N 3.27Å; N634-A638 PolarHBondContact O-N 3.05Å
635L82.2Confident79.2Confident0 Ų050.3 Ų50.30%031%0.311CS..Hα-helixtrans-67.5-40.6174.8-173.458.8000111.8V571 I579 L594 L619 W622 T631 V632 T637 A638 L639 L651V571-L635 HydrophobicContact CG1-CD2 3.9Å; V571-L635 HydrophobicContact CG2-CB 4.14Å; V571-L635 HydrophobicContact CG2-CD2 3.87Å; I579-L635 HydrophobicContact CD1-CD2 3.75Å; L594-L635 HydrophobicContact CD2-CD1 4.42Å; L619-L635 HydrophobicContact CD2-CD1 3.89Å; L619-L635 HydrophobicContact CD2-CD2 4.35Å; W622-L635 HydrophobicContact CE3-CD1 4.37Å; W622-L635 HydrophobicContact CH2-CB 3.75Å; W622-L635 HydrophobicContact CH2-CD1 4.32Å; W622-L635 HydrophobicContact CH2-CG 4.47Å; W622-L635 HydrophobicContact CZ2-CB 4.5Å; W622-L635 HydrophobicContact CZ3-CB 4.08Å; W622-L635 HydrophobicContact CZ3-CD1 4.13Å; W622-L635 HydrophobicContact CZ3-CD2 4.22Å; W622-L635 HydrophobicContact CZ3-CG 4.37Å; T631-L635 PolarHBondContact O-N 3.24Å; T631-L635 VanDerWaalsContact O-N 3.13Å; V632-L635 PolarHBondContact O-N 3.45Å; L635-T637 VanDerWaalsContact C-N 3.31Å; L635-T637 PolarHBondContact O-N 3.35Å; L635-A638 PolarHBondContact O-N 2.75Å; L635-L639 HydrophobicContact CD1-CG 4.5Å; L635-L639 HydrophobicContact CG-CD1 4.07Å; L635-L639 WeakPolarHBondContact O-CB 3.12Å; L635-L639 VanDerWaalsContact O-CG 3.3Å; L635-L639 WeakPolarHBondContact O-CG 3.33Å; L635-L639 PolarHBondContact O-N 3.4Å; L635-L651 HydrophobicContact CB-CD2 3.92Å; L635-L651 HydrophobicContact CD2-CD2 3.8Å; L635-L651 HydrophobicContact CG-CD2 3.76Å
636A82Confident78.9Confident15 Ų1552.7 Ų52.712%0.12433%0.326CS..Hα-helixtrans-63.4-37.2175.700000112.2V632 E633 S640 A648 L651V632-A636 VanDerWaalsContact O-CB 3.27Å; V632-A636 WeakPolarHBondContact O-CB 3.49Å; V632-A636 PolarHBondContact O-N 2.98Å; E633-A636 PolarHBondContact O-N 3.35Å; A636-S640 WeakPolarHBondContact O-CB 3.48Å; A636-S640 PolarHBondContact O-N 3Å; A636-S640 PolarHBondContact O-OG 3.45Å; A636-A648 HydrophobicContact CB-CB 4.18Å; A636-A648 VanDerWaalsContact O-CB 3.25Å; A636-A648 WeakPolarHBondContact O-CB 3.37Å; A636-L651 HydrophobicContact CB-CD2 4.33Å
637T83.9Confident79Confident94 Ų9450.5 Ų50.558%0.57732%0.317SS*.Hα-helixtrans-66.2-45.4175.3-560000111E633 N634 L635 S640 A641E633-T637 WeakPolarHBondContact O-CB 3.49Å; E633-T637 PolarHBondContact O-N 3.49Å; E633-T637 PolarHBondContact O-OG1 3.18Å; N634-T637 PolarHBondContact O-N 3.27Å; L635-T637 VanDerWaalsContact C-N 3.31Å; L635-T637 PolarHBondContact O-N 3.35Å; T637-S640 PolarHBondContact O-N 3.36Å; T637-A641 WeakPolarHBondContact O-CB 3.39Å; T637-A641 PolarHBondContact O-N 3.42Å
638A81.8Confident79Confident13 Ų1348.8 Ų48.811%0.10730%0.298CS..Hα-helixtrans-64.8-40.6176.800000112.7L590 L594 N634 L635 A641 A642L590-A638 HydrophobicContact CD1-CB 4.4Å; L594-A638 HydrophobicContact CD2-CB 3.41Å; L594-A638 VanDerWaalsContact CD2-CB 3.41Å; L594-A638 HydrophobicContact CG-CB 4.32Å; N634-A638 PolarHBondContact O-N 3.05Å; L635-A638 PolarHBondContact O-N 2.75Å; A638-A641 PolarHBondContact O-N 3.41Å; A638-A642 WeakPolarHBondContact O-CB 3.48Å; A638-A642 PolarHBondContact O-N 3.04Å
639L82.7Confident79.4Confident0 Ų050.2 Ų50.20%029%0.294CS..Hα-helixtrans-63.2-41.9174.5-76.8167.2000111.9I579 L583 L590 L635 A642 G643 F644 L647 A648 L651I579-L639 HydrophobicContact CD1-CD1 4.26Å; I579-L639 HydrophobicContact CG2-CD1 4.49Å; I579-L639 HydrophobicContact CG2-CD2 4.37Å; L583-L639 HydrophobicContact CD1-CD2 4.24Å; L590-L639 HydrophobicContact CD1-CD2 3.82Å; L590-L639 HydrophobicContact CD1-CG 4.18Å; L590-L639 HydrophobicContact CD2-CD2 3.75Å; L590-L639 HydrophobicContact CG-CD2 4.41Å; L635-L639 HydrophobicContact CD1-CG 4.5Å; L635-L639 HydrophobicContact CG-CD1 4.07Å; L635-L639 WeakPolarHBondContact O-CB 3.12Å; L635-L639 VanDerWaalsContact O-CG 3.3Å; L635-L639 WeakPolarHBondContact O-CG 3.33Å; L635-L639 PolarHBondContact O-N 3.4Å; L639-A642 PolarHBondContact O-N 3.17Å; L639-G643 PolarHBondContact O-N 2.98Å; L639-F644 HydrophobicContact CB-CB 4.37Å; L639-F644 HydrophobicContact CD2-CB 4.17Å; L639-F644 HydrophobicContact CD2-CD2 4.28Å; L639-F644 WeakPolarHBondContact O-CA 3.28Å; L639-F644 WeakPolarHBondContact O-CB 3.49Å; L639-F644 PolarHBondContact O-N 3.32Å; L639-L647 HydrophobicContact CD1-CB 4.47Å; L639-A648 HydrophobicContact CB-CB 4.03Å; L639-L651 HydrophobicContact CD1-CD2 3.91Å
640S82Confident79.7Confident55 Ų5551.8 Ų51.839%0.38530%0.295SS..Hα-helixtrans-64.6-43.2176-62.70000111.7A636 T637 A642 G643 A648A636-S640 WeakPolarHBondContact O-CB 3.48Å; A636-S640 PolarHBondContact O-N 3Å; A636-S640 PolarHBondContact O-OG 3.45Å; T637-S640 PolarHBondContact O-N 3.36Å; S640-A642 VanDerWaalsContact C-N 3.27Å; S640-A642 PolarHBondContact O-N 3.09Å; S640-G643 PolarHBondContact O-N 3.12Å; S640-G643 VanDerWaalsContact O-N 3.11Å; S640-A648 WeakPolarHBondContact OG-CB 3.32Å
641A81.9Confident79.5Confident65 Ų6552.1 Ų52.154%0.53730%0.296SS..Hα-helixtrans-63.7-33.2176.600000112.4H593 T637 A638 G643H593-A641 PolarHBondContact CE1-O 3.04Å; T637-A641 WeakPolarHBondContact O-CB 3.39Å; T637-A641 PolarHBondContact O-N 3.42Å; A638-A641 PolarHBondContact O-N 3.41Å; A641-G643 VanDerWaalsContact C-N 3.26Å; A641-G643 PolarHBondContact O-N 3.02Å
642A79.6Confident78.4Confident13 Ų1354.2 Ų54.211%0.10732%0.321CS..THydrogen-bonded Turntrans-79.60.1175.800000114.3L590 H593 A638 L639 S640 F644L590-A642 HydrophobicContact CD1-CB 4.03Å; H593-A642 HydrophobicContact CB-CB 4.29Å; H593-A642 VanDerWaalsContact CD2-CA 3.48Å; H593-A642 WeakPolarHBondContact CD2-CA 3.45Å; H593-A642 VanDerWaalsContact CD2-CB 3.47Å; H593-A642 WeakPolarHBondContact CD2-CB 3.44Å; A638-A642 WeakPolarHBondContact O-CB 3.48Å; A638-A642 PolarHBondContact O-N 3.04Å; L639-A642 PolarHBondContact O-N 3.17Å; S640-A642 VanDerWaalsContact C-N 3.27Å; S640-A642 PolarHBondContact O-N 3.09Å; A642-F644 HydrophobicContact CB-CD2 3.72Å; A642-F644 HydrophobicContact CB-CE2 3.9Å
643G77.5Confident77.3Confident59 Ų5961.6 Ų61.661%0.60836%0.355SS*.THydrogen-bonded Turntrans89.49.417800000115.2L639 S640 A641 S645L639-G643 PolarHBondContact O-N 2.98Å; S640-G643 PolarHBondContact O-N 3.12Å; S640-G643 VanDerWaalsContact O-N 3.11Å; A641-G643 VanDerWaalsContact C-N 3.26Å; A641-G643 PolarHBondContact O-N 3.02Å; G643-S645 PolarHBondContact O-N 3.26Å
644F82.9Confident75.8Confident31 Ų3159 Ų5914%0.13636%0.355CS..  trans-98.349.1179.3-57.8-73.4000112.8L583 Q586 L639 A642 Q646 L647 A648L583-F644 HydrophobicContact CD1-CD2 4.04Å; L583-F644 HydrophobicContact CD1-CE1 4.32Å; L583-F644 HydrophobicContact CD1-CE2 3.82Å; L583-F644 HydrophobicContact CD1-CG 4.41Å; L583-F644 HydrophobicContact CD1-CZ 3.99Å; Q586-F644 HydrophobicContact CB-CE1 4.21Å; Q586-F644 HydrophobicContact CB-CZ 3.64Å; Q586-F644 VanDerWaalsContact OE1-CZ 3.23Å; L639-F644 HydrophobicContact CB-CB 4.37Å; L639-F644 HydrophobicContact CD2-CB 4.17Å; L639-F644 HydrophobicContact CD2-CD2 4.28Å; L639-F644 WeakPolarHBondContact O-CA 3.28Å; L639-F644 WeakPolarHBondContact O-CB 3.49Å; L639-F644 PolarHBondContact O-N 3.32Å; A642-F644 HydrophobicContact CB-CD2 3.72Å; A642-F644 HydrophobicContact CB-CE2 3.9Å; F644-Q646 PolarHBondContact O-N 3.39Å; F644-L647 HydrophobicContact CB-CB 4.16Å; F644-L647 HydrophobicContact CB-CD1 4.09Å; F644-L647 HydrophobicContact CB-CG 4.33Å; F644-L647 HydrophobicContact CD1-CD1 4.15Å; F644-L647 HydrophobicContact CG-CD1 4.3Å; F644-L647 PolarHBondContact O-N 3.49Å; F644-A648 PolarHBondContact O-N 3.1Å
645S76.4Confident75.6Confident61 Ų6158.5 Ų58.543%0.42735%0.354SS..Hα-helixtrans-56.5-35.5-175.3-49.50000113.4G643 L647 A648 E649G643-S645 PolarHBondContact O-N 3.26Å; S645-L647 VanDerWaalsContact C-N 3.32Å; S645-L647 PolarHBondContact O-N 3.5Å; S645-A648 PolarHBondContact O-N 2.84Å; S645-E649 WeakPolarHBondContact O-CG 3.46Å; S645-E649 PolarHBondContact O-N 3.48Å
646Q75.6Confident75.2Confident147 Ų14761.6 Ų61.669%0.68737%0.373SS*.Hα-helixtrans-67.9-27.8176.6-65.8-178.75.900113.6F644 R650F644-Q646 PolarHBondContact O-N 3.39Å; Q646-R650 WeakPolarHBondContact O-CG 3.21Å; Q646-R650 PolarHBondContact O-N 3.2Å
647L78.4Confident74.9Confident23 Ų2364.2 Ų64.212%0.1239%0.386CS..Hα-helixtrans-80.8-35.8174.5-64.9-179.9000110.9K582 L639 F644 S645 L651K582-L647 HydrophobicContact CB-CD1 4.18Å; K582-L647 HydrophobicContact CB-CD2 3.72Å; K582-L647 HydrophobicContact CD-CD2 3.47Å; K582-L647 VanDerWaalsContact CD-CD2 3.47Å; K582-L647 HydrophobicContact CG-CD2 4.24Å; L639-L647 HydrophobicContact CD1-CB 4.47Å; F644-L647 HydrophobicContact CB-CB 4.16Å; F644-L647 HydrophobicContact CB-CD1 4.09Å; F644-L647 HydrophobicContact CB-CG 4.33Å; F644-L647 HydrophobicContact CD1-CD1 4.15Å; F644-L647 HydrophobicContact CG-CD1 4.3Å; F644-L647 PolarHBondContact O-N 3.49Å; S645-L647 VanDerWaalsContact C-N 3.32Å; S645-L647 PolarHBondContact O-N 3.5Å; L647-L651 VanDerWaalsContact O-CB 3.29Å; L647-L651 WeakPolarHBondContact O-CB 3.47Å; L647-L651 PolarHBondContact O-N 2.96Å
648A75.9Confident74.3Confident7 Ų762.4 Ų62.46%0.05838%0.375CS..Hα-helixtrans-65-43.2174.500000112.4A636 L639 S640 F644 S645 L651 G652A636-A648 HydrophobicContact CB-CB 4.18Å; A636-A648 VanDerWaalsContact O-CB 3.25Å; A636-A648 WeakPolarHBondContact O-CB 3.37Å; L639-A648 HydrophobicContact CB-CB 4.03Å; S640-A648 WeakPolarHBondContact OG-CB 3.32Å; F644-A648 PolarHBondContact O-N 3.1Å; S645-A648 PolarHBondContact O-N 2.84Å; A648-L651 PolarHBondContact O-N 3.39Å; A648-G652 PolarHBondContact O-N 3.4Å
649E74.7Confident73.9Confident130 Ų13065.5 Ų65.561%0.60739%0.392SS*.Hα-helixtrans-61.3-46.9176.3-76.3174.4176.700111.5S645 L651 G652 E653S645-E649 WeakPolarHBondContact O-CG 3.46Å; S645-E649 PolarHBondContact O-N 3.48Å; E649-L651 VanDerWaalsContact C-N 3.27Å; E649-L651 PolarHBondContact O-N 3.17Å; E649-G652 PolarHBondContact O-N 3.03Å; E649-E653 WeakPolarHBondContact O-CG 3.4Å; E649-E653 PolarHBondContact O-N 3.07Å
650R73.7Confident73.3Confident149 Ų14969.9 Ų69.956%0.56242%0.418SS*.Hα-helixtrans-65.7-29.1177.5-73.1-178.8-177.4-172.52.9113.7Q646Q646-R650 WeakPolarHBondContact O-CG 3.21Å; Q646-R650 PolarHBondContact O-N 3.2Å
651L72.8Confident72.6Confident8 Ų870.9 Ų70.94%0.04242%0.42CS..Hα-helixtrans-75.4-33.1176.2-178.660.6000111.3Q575 I579 V632 L635 A636 L639 L647 A648 E649Q575-L651 HydrophobicContact CB-CD1 4.12Å; Q575-L651 HydrophobicContact CG-CD1 4.24Å; I579-L651 HydrophobicContact CD1-CD1 3.93Å; I579-L651 HydrophobicContact CD1-CD2 3.83Å; I579-L651 HydrophobicContact CD1-CG 4.35Å; V632-L651 HydrophobicContact CG1-CD1 4Å; V632-L651 HydrophobicContact CG1-CD2 4.42Å; V632-L651 HydrophobicContact CG1-CG 3.72Å; V632-L651 WeakPolarHBondContact CG1-O 3.42Å; L635-L651 HydrophobicContact CB-CD2 3.92Å; L635-L651 HydrophobicContact CD2-CD2 3.8Å; L635-L651 HydrophobicContact CG-CD2 3.76Å; A636-L651 HydrophobicContact CB-CD2 4.33Å; L639-L651 HydrophobicContact CD1-CD2 3.91Å; L647-L651 VanDerWaalsContact O-CB 3.29Å; L647-L651 WeakPolarHBondContact O-CB 3.47Å; L647-L651 PolarHBondContact O-N 2.96Å; A648-L651 PolarHBondContact O-N 3.39Å; E649-L651 VanDerWaalsContact C-N 3.27Å; E649-L651 PolarHBondContact O-N 3.17Å
652G59.9Low71.9Confident59 Ų5971.4 Ų71.461%0.60841%0.411SS*.Hα-helixtrans-76.4-22.2174.400000114.5A648 E649A648-G652 PolarHBondContact O-N 3.4Å; E649-G652 PolarHBondContact O-N 3.03Å
653E57.1Low71.3Confident169 Ų16976.3 Ų76.379%0.7944%0.437SS*.  trans-83.1-9.3177.1-73.6179.2169.200114.3E649E649-E653 WeakPolarHBondContact O-CG 3.4Å; E649-E653 PolarHBondContact O-N 3.07Å
654A50.6Low70.7Confident72 Ų7277.8 Ų77.860%0.59542%0.421SS*.  trans-112.30-176.600000112.6Q575Q575-A654 PolarHBondContact NE2-OXT 2.88Å

Retrieved 654 of 654 residues in 525.7 ms (Link to these results)