A0A096MEU1_POEFO Loading...

TBC1 domain family member 22B

May act as a GTPase-activating protein for Rab family protein(s).

AlphaFold DB , UniProt , Accession A0A096MEU1, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 531 aa.

Structure Viewer

Loading PAE data...

(Predicted Aligned Error values between residue pairs)

Download Structure PDB PAE Table

Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	34.3	Very low	32.7	Very low	244 Å²	244	173.8 Å²	173.8	100%	1.202	83%	0.833	S	S	*	*				0	146.8	0	-75	174.5	164.9	0	0	108.2
2	A	35.4	Very low	32.3	Very low	102 Å²	102	180.2 Å²	180.2	84%	0.843	84%	0.843	S	S	*	*			trans	49.6	101.7	171.4	0	0	0	0	0	118
3	T	33.9	Very low	32	Very low	125 Å²	125	178.5 Å²	178.5	77%	0.767	84%	0.843	S	S	*	*			trans	-99.8	-167.8	150.1	51.8	0	0	0	0	109.3
4	D	32.5	Very low	31.9	Very low	129 Å²	129	173.9 Å²	173.9	69%	0.69	83%	0.833	S	S	*	*			trans	79.6	147.8	162.9	-70.1	55.9	0	0	0	118.2
5	N	33.2	Very low	31.8	Very low	125 Å²	125	175.9 Å²	175.9	67%	0.668	84%	0.836	S	S	*	*			cis	-160.1	126.9	-35.4	-120.9	-37	0	0	0	108.9	I7	N5-I7 PolarHBondContact O-N 2.85Å
6	R	33.1	Very low	31.8	Very low	242 Å²	242	173.3 Å²	173.3	91%	0.913	84%	0.835	S	S	*	*			trans	-92.6	99.4	175.5	-78.2	-171	178.9	-178.5	0.8	110.9	N8	R6-N8 PolarHBondContact O-N 2.61Å
7	I	38.3	Very low	31.8	Very low	127 Å²	127	170.9 Å²	170.9	65%	0.651	84%	0.836	S	S	*	*			trans	-85.8	111.7	179	-59.6	179.2	0	0	0	110.6	N5 F9	N5-I7 PolarHBondContact O-N 2.85Å; I7-F9 HydrophobicContact CG2-CD2 3.87Å; I7-F9 HydrophobicContact CG2-CE2 3.79Å
8	N	29.7	Very low	31.5	Very low	149 Å²	149	165.3 Å²	165.3	80%	0.797	83%	0.831	S	S	*	*			trans	-83.1	115.1	172.8	-69.3	-40.7	0	0	0	110.4	R6 W10	R6-N8 PolarHBondContact O-N 2.61Å; N8-W10 PolarHBondContact O-N 2.85Å
9	F	29.5	Very low	31.2	Very low	178 Å²	178	162.8 Å²	162.8	78%	0.781	83%	0.83	S	S	*	*			trans	-83.6	7.5	-166.6	-110.9	-84.5	0	0	0	117.2	I7	I7-F9 HydrophobicContact CG2-CD2 3.87Å; I7-F9 HydrophobicContact CG2-CE2 3.79Å
10	W	28.6	Very low	31.1	Very low	248 Å²	248	161.4 Å²	161.4	94%	0.939	83%	0.829	S	S	*	*			trans	-126.8	86.5	-176.8	-62.5	109.9	0	0	0	113	N8	N8-W10 PolarHBondContact O-N 2.85Å
11	R	31.1	Very low	31	Very low	243 Å²	243	161.7 Å²	161.7	92%	0.917	83%	0.827	S	S	*	*			trans	-95.4	121.4	157.1	-76.4	-167.4	179.7	-139.4	3.3	109.4
12	R	28.4	Very low	30.7	Very low	250 Å²	250	155.5 Å²	155.5	94%	0.943	81%	0.805	S	S	*	*			trans	-67.1	137.7	160.8	-62.9	177	-175.4	155.7	1.8	108
13	N	28.4	Very low	30.6	Very low	159 Å²	159	157.3 Å²	157.3	85%	0.85	81%	0.805	S	S	*	*			trans	-130.3	155.7	165.3	-155	3.3	0	0	0	109.8
14	T	30.1	Very low	30.4	Very low	113 Å²	113	161.7 Å²	161.7	69%	0.693	81%	0.809	S	S	*	*			trans	-124.2	150.2	-164.3	56.5	0	0	0	0	113.3
15	K	30.8	Very low	30.5	Very low	204 Å²	204	159.3 Å²	159.3	89%	0.887	82%	0.816	S	S	*	*			trans	82.5	134.4	174.4	-53.2	179.1	-179.2	179.8	0	116.2
16	V	31.1	Very low	30.4	Very low	135 Å²	135	158.1 Å²	158.1	82%	0.818	82%	0.823	S	S	*	*			trans	-105.2	156.5	162.1	-138.8	0	0	0	0	106.5
17	P	33	Very low	30.4	Very low	132 Å²	132	155.1 Å²	155.1	86%	0.857	82%	0.819	S	S	*	*				-146.3	160	81.6	38.2	-21.4	0	0	0	115.5
18	G	26.1	Very low	30.1	Very low	71 Å²	71	157.8 Å²	157.8	73%	0.732	83%	0.828	S	S	*	*			trans	116.3	94.6	157.8	0	0	0	0	0	117.6
19	S	25.4	Very low	30.5	Very low	118 Å²	118	155.9 Å²	155.9	83%	0.825	83%	0.825	S	S	*	*			trans	19.7	115.7	143.3	170.3	0	0	0	0	120.2
20	V	28.2	Very low	30.8	Very low	133 Å²	133	153.7 Å²	153.7	81%	0.806	83%	0.828	S	S	*	*				-169	148	117.7	139.3	0	0	0	0	111.8
21	Q	30.6	Very low	31	Very low	169 Å²	169	149.9 Å²	149.9	79%	0.79	83%	0.825	S	S	*	*			trans	-16	155.4	178.8	-62.4	-178.2	-9.8	0	0	123.2
22	P	28.4	Very low	31.2	Very low	113 Å²	113	144 Å²	144	73%	0.734	81%	0.812	S	S	*	*			trans	-80	147.8	169.6	35	-35.1	0	0	0	112.9
23	V	31.4	Very low	31.5	Very low	141 Å²	141	137.8 Å²	137.8	86%	0.855	80%	0.804	S	S	*	*			trans	-110.6	119	175	178.7	0	0	0	0	109.9
24	Y	31.3	Very low	31.8	Very low	216 Å²	216	140.6 Å²	140.6	85%	0.847	80%	0.803	S	S	*	*	P	Polyproline II helix	trans	-81.2	138.7	169.1	-87.3	-93.7	0	0	0	110.8
25	G	33.3	Very low	32	Very low	80 Å²	80	143.5 Å²	143.5	83%	0.825	81%	0.813	S	S	*	*	P	Polyproline II helix	trans	-79	123	170.5	0	0	0	0	0	110.9
26	A	32.2	Very low	32	Very low	99 Å²	99	145.5 Å²	145.5	82%	0.818	82%	0.815	S	S	*	*	P	Polyproline II helix	trans	-84.1	136.5	-178.8	0	0	0	0	0	112.6
27	Q	32.2	Very low	31.8	Very low	179 Å²	179	150.9 Å²	150.9	84%	0.836	82%	0.82	S	S	*	*			trans	-111.5	116.5	153.7	-69.5	-174.8	-5.1	0	0	107.6
28	H	33.3	Very low	31.6	Very low	183 Å²	183	150.1 Å²	150.1	85%	0.847	81%	0.813	S	S	*	*	S	Bend	trans	149.8	135.2	160.2	-78.6	-49.4	0	0	0	108.9
29	P	36.5	Very low	31.7	Very low	110 Å²	110	157.3 Å²	157.3	71%	0.714	82%	0.82	S	S	*	*	P	Polyproline II helix	trans	-77.3	151.7	178.8	32	-34.7	0	0	0	112.2
30	P	35.8	Very low	32.1	Very low	131 Å²	131	157 Å²	157	85%	0.851	82%	0.816	S	S	*	*	P	Polyproline II helix	trans	-73.7	145.5	-179.8	30.4	-35.2	0	0	0	112.7
31	L	33.8	Very low	32.2	Very low	168 Å²	168	160.2 Å²	160.2	88%	0.88	82%	0.819	S	S	*	*	P	Polyproline II helix	trans	-93.6	149.5	178.4	-65.7	170.2	0	0	0	112.2
32	D	34.8	Very low	32.1	Very low	119 Å²	119	159.3 Å²	159.3	64%	0.636	82%	0.819	S	S	*	*	P	Polyproline II helix	trans	-70.2	126.8	-178	-174.1	-31.9	0	0	0	112.1	R34	D32-R34 PolarHBondContact O-N 3.37Å; D32-R34 VanDerWaalsContact O-N 3.11Å; D32-R34 VanDerWaalsContact OD1-CB 3.3Å; D32-R34 WeakPolarHBondContact OD1-CB 3.38Å; D32-R34 WeakPolarHBondContact OD1-CG 3.15Å; D32-R34 PolarHBondContact OD1-N 3.15Å
33	P	34.3	Very low	32.1	Very low	120 Å²	120	159.8 Å²	159.8	78%	0.779	82%	0.82	S	S	*	*	T	Hydrogen-bonded Turn	trans	-74.8	11.2	-177	31.8	-37.4	0	0	0	116.1
34	R	34.7	Very low	32	Very low	219 Å²	219	162.2 Å²	162.2	83%	0.826	82%	0.819	S	S	*	*	T	Hydrogen-bonded Turn	trans	-92.7	11.5	-172.2	-73.8	-178.1	164.1	173.5	-2.5	117.9	D32	D32-R34 PolarHBondContact O-N 3.37Å; D32-R34 VanDerWaalsContact O-N 3.11Å; D32-R34 VanDerWaalsContact OD1-CB 3.3Å; D32-R34 WeakPolarHBondContact OD1-CB 3.38Å; D32-R34 WeakPolarHBondContact OD1-CG 3.15Å; D32-R34 PolarHBondContact OD1-N 3.15Å
35	L	34.2	Very low	31.8	Very low	173 Å²	173	157.9 Å²	157.9	91%	0.906	82%	0.817	S	S	*	*			trans	-115.9	83.4	175.1	-68.9	175.7	0	0	0	113.1
36	R	30.6	Very low	31.4	Very low	246 Å²	246	163 Å²	163	93%	0.928	82%	0.817	S	S	*	*			trans	-105.5	113.2	162.2	-77.3	-172.3	176.9	-117.5	0.1	110.2
37	R	28.7	Very low	31.2	Very low	248 Å²	248	167.2 Å²	167.2	94%	0.936	82%	0.817	S	S	*	*			trans	-111.9	117.2	168.2	-135	175.7	-171.7	171.6	2.4	108.6
38	T	29.1	Very low	30.9	Very low	116 Å²	116	165.1 Å²	165.1	71%	0.712	81%	0.812	S	S	*	*			trans	-81.9	145.4	175.2	48.3	0	0	0	0	111
39	Y	27.1	Very low	30.6	Very low	222 Å²	222	162.9 Å²	162.9	87%	0.871	81%	0.806	S	S	*	*			trans	-163.4	171.9	143.4	-94	-48.3	0	0	0	109.9
40	P	34	Very low	30.1	Very low	113 Å²	113	164.7 Å²	164.7	73%	0.734	81%	0.809	S	S	*	*				-101.6	175.8	-129.4	40	-38.6	0	0	0	116.6
41	K	29.9	Very low	29.7	Very low	200 Å²	200	167.4 Å²	167.4	87%	0.87	81%	0.807	S	S	*	*			trans	-71	152.2	163.7	-61.9	172.1	176.3	175.5	0	110.4
42	D	28.1	Very low	29.9	Very low	149 Å²	149	165 Å²	165	80%	0.797	80%	0.804	S	S	*	*			trans	-147.1	151.3	150.1	-124.3	-46.2	0	0	0	116.3
43	T	29	Very low	29.7	Very low	123 Å²	123	169.4 Å²	169.4	76%	0.755	82%	0.818	S	S	*	*			trans	2.1	146.3	165.9	-56.2	0	0	0	0	123.5
44	K	28.8	Very low	29.5	Very low	192 Å²	192	173.2 Å²	173.2	84%	0.835	82%	0.822	S	S	*	*			trans	-97.9	153.2	167.5	-59.4	179	178.5	-177.7	0	112.7
45	P	27.4	Very low	29.4	Very low	125 Å²	125	167.7 Å²	167.7	81%	0.812	82%	0.824	S	S	*	*			trans	-98	177.1	152.1	34.3	-28	0	0	0	113.7
46	K	25.4	Very low	29.2	Very low	187 Å²	187	164 Å²	164	81%	0.813	81%	0.811	S	S	*	*			trans	-146.6	178.3	177.3	-103.2	-169.4	175.8	-173.2	0	109.2
47	F	27.1	Very low	29.7	Very low	188 Å²	188	155.8 Å²	155.8	83%	0.825	79%	0.792	S	S	*	*			trans	80.3	141.2	177.5	-62.9	-86.8	0	0	0	114.8
48	N	26.1	Very low	30.2	Very low	135 Å²	135	152.4 Å²	152.4	72%	0.722	78%	0.784	S	S	*	*			cis	-153.6	-176.9	-15.4	-140.8	4.1	0	0	0	113
49	N	27.5	Very low	30.5	Very low	137 Å²	137	153.7 Å²	153.7	73%	0.733	78%	0.782	S	S	*	*			trans	-73.7	177.8	-173.4	-66.9	-45.4	0	0	0	117.4
50	L	26.5	Very low	31.1	Very low	147 Å²	147	148.3 Å²	148.3	77%	0.77	76%	0.764	S	S	*	*			trans	93.3	139.6	175.3	-75.4	59.9	0	0	0	113.8
51	K	26.4	Very low	31.3	Very low	188 Å²	188	150 Å²	150	82%	0.817	76%	0.761	S	S	*	*			cis	-149.7	158.1	9.8	-121.7	157.5	-176	170.1	0	110.3
52	S	38	Very low	32	Very low	117 Å²	117	142.7 Å²	142.7	82%	0.818	74%	0.738	S	S	*	*			trans	-78.9	143.6	172.9	49.8	0	0	0	0	112.9
53	K	30	Very low	32.4	Very low	212 Å²	212	138.9 Å²	138.9	92%	0.922	72%	0.722	S	S	*	*			trans	-140.5	167.8	162.6	-87.4	-168.2	176.1	-179.7	0	110.5
54	K	30.8	Very low	32.7	Very low	200 Å²	200	136.7 Å²	136.7	87%	0.87	71%	0.711	S	S	*	*	P	Polyproline II helix	trans	-75.1	165.9	-166.3	-62.7	178.4	178	179.9	0	112.9
55	A	31.9	Very low	33.3	Very low	104 Å²	104	131 Å²	131	86%	0.86	69%	0.693	S	S	*	*	P	Polyproline II helix	trans	-61.3	132.1	166.5	0	0	0	0	0	111.1
56	C	31.4	Very low	33.9	Very low	94 Å²	94	129 Å²	129	64%	0.635	68%	0.675	S	S	*	*	P	Polyproline II helix	trans	-83.4	163.7	168.8	-83.8	0	0	0	0	111	E60	C56-E60 WeakPolarHBondContact CA-OE2 3.38Å; C56-E60 HydrophobicContact CB-CB 4.45Å; C56-E60 WeakPolarHBondContact CB-OE2 3.01Å; C56-E60 PolarHBondContact SG-OE2 3.47Å; C56-E60 VanDerWaalsContact SG-OE2 3.4Å
57	S	41.1	Very low	34.4	Very low	75 Å²	75	125.5 Å²	125.5	52%	0.524	67%	0.665	S	S	.	*	P	Polyproline II helix	trans	-76	149.8	177	-174.2	0	0	0	0	111.3	H59 E60	S57-H59 PolarHBondContact O-N 3.04Å; S57-E60 PolarHBondContact N-OE2 3.23Å; S57-E60 PolarHBondContact O-N 3.3Å
58	F	39	Very low	34.7	Very low	176 Å²	176	119.9 Å²	119.9	77%	0.772	65%	0.654	S	S	*	*	H	α-helix	trans	-51.8	-30.8	175.5	-177.1	-109.9	0	0	0	112.8	F61	F58-F61 PolarHBondContact O-N 3.39Å
59	H	35.4	Very low	35.7	Very low	144 Å²	144	123.4 Å²	123.4	67%	0.667	66%	0.657	S	S	*	*	H	α-helix	trans	-70	-32.4	179	-153.2	64.8	0	0	0	113.7	S57 F61 A62	S57-H59 PolarHBondContact O-N 3.04Å; H59-F61 VanDerWaalsContact C-N 3.32Å; H59-F61 PolarHBondContact O-N 3.37Å; H59-A62 PolarHBondContact O-N 2.91Å
60	E	39.2	Very low	36.4	Very low	108 Å²	108	123.7 Å²	123.7	51%	0.505	66%	0.659	S	S	.	*	H	α-helix	trans	-68.7	-33.1	177.9	-70	171.5	103.1	0	0	111.7	C56 S57 C63 S64	C56-E60 WeakPolarHBondContact CA-OE2 3.38Å; C56-E60 HydrophobicContact CB-CB 4.45Å; C56-E60 WeakPolarHBondContact CB-OE2 3.01Å; C56-E60 PolarHBondContact SG-OE2 3.47Å; C56-E60 VanDerWaalsContact SG-OE2 3.4Å; S57-E60 PolarHBondContact N-OE2 3.23Å; S57-E60 PolarHBondContact O-N 3.3Å; E60-C63 PolarHBondContact O-N 2.4Å; E60-S64 PolarHBondContact O-N 3.16Å
61	F	38.6	Very low	36.8	Very low	149 Å²	149	123.7 Å²	123.7	65%	0.654	66%	0.658	S	S	*	*	H	α-helix	trans	-65.7	-41.5	178.8	-167.5	-96.9	0	0	0	111.9	F58 H59 C63 S64 T65	F58-F61 PolarHBondContact O-N 3.39Å; H59-F61 VanDerWaalsContact C-N 3.32Å; H59-F61 PolarHBondContact O-N 3.37Å; F61-C63 PolarHBondContact O-N 2.86Å; F61-S64 PolarHBondContact O-N 3.19Å; F61-T65 HydrophobicContact CD1-CG2 4.3Å; F61-T65 HydrophobicContact CE1-CG2 3.93Å; F61-T65 HydrophobicContact CZ-CG2 4.27Å; F61-T65 PolarHBondContact O-N 3.47Å; F61-T65 VanDerWaalsContact O-N 3.09Å; F61-T65 PolarHBondContact O-OG1 2.92Å
62	A	43.4	Very low	37.3	Very low	47 Å²	47	121.5 Å²	121.5	39%	0.388	66%	0.655	S	S	.	*	H	α-helix	trans	-63	-38.2	179.1	0	0	0	0	0	112.9	H59 T65 N66	H59-A62 PolarHBondContact O-N 2.91Å; A62-T65 PolarHBondContact O-OG1 3.4Å; A62-N66 PolarHBondContact O-ND2 2.95Å
63	C	37.8	Very low	36.9	Very low	68 Å²	68	124.4 Å²	124.4	46%	0.459	66%	0.662	S	S	.	*	H	α-helix	trans	-66.2	-51	171.8	-64.5	0	0	0	0	111	E60 F61 T65 N66 D67	E60-C63 PolarHBondContact O-N 2.4Å; F61-C63 PolarHBondContact O-N 2.86Å; C63-T65 PolarHBondContact O-N 3.36Å; C63-N66 PolarHBondContact O-N 3.21Å; C63-D67 PolarHBondContact O-N 3.09Å
64	S	34.3	Very low	37.2	Very low	77 Å²	77	123.4 Å²	123.4	54%	0.538	66%	0.66	S	S	.	*	H	α-helix	trans	-57.4	-22.9	-179.5	-173.1	0	0	0	0	114.4	E60 F61	E60-S64 PolarHBondContact O-N 3.16Å; F61-S64 PolarHBondContact O-N 3.19Å
65	T	42.1	Very low	37.4	Very low	74 Å²	74	123.1 Å²	123.1	45%	0.454	66%	0.662	S	S	.	*	H	α-helix	trans	-87.4	-10.8	174.6	49.9	0	0	0	0	115.4	F61 A62 C63	F61-T65 HydrophobicContact CD1-CG2 4.3Å; F61-T65 HydrophobicContact CE1-CG2 3.93Å; F61-T65 HydrophobicContact CZ-CG2 4.27Å; F61-T65 PolarHBondContact O-N 3.47Å; F61-T65 VanDerWaalsContact O-N 3.09Å; F61-T65 PolarHBondContact O-OG1 2.92Å; A62-T65 PolarHBondContact O-OG1 3.4Å; C63-T65 PolarHBondContact O-N 3.36Å
66	N	40.4	Very low	37.3	Very low	82 Å²	82	125.9 Å²	125.9	44%	0.439	66%	0.662	S	S	.	*	H	α-helix	trans	-81.5	-45.2	168.9	-78.4	-96.6	0	0	0	110.4	A62 C63 A68 R204	A62-N66 PolarHBondContact O-ND2 2.95Å; C63-N66 PolarHBondContact O-N 3.21Å; N66-A68 VanDerWaalsContact C-N 3.34Å; N66-A68 PolarHBondContact O-N 3.01Å; N66-R204 PolarHBondContact OD1-NH2 3.48Å
67	D	35.9	Very low	37.2	Very low	113 Å²	113	129.2 Å²	129.2	60%	0.604	67%	0.674	S	S	*	*	H	α-helix	trans	-75.1	-20.7	-170	-52.3	-15.7	0	0	0	113.3	C63 W69 D70	C63-D67 PolarHBondContact O-N 3.09Å; D67-W69 PolarHBondContact O-N 2.57Å; D67-D70 PolarHBondContact O-N 3.36Å
68	A	33.4	Very low	36.5	Very low	71 Å²	71	133 Å²	133	59%	0.587	69%	0.688	S	S	*	*	T	Hydrogen-bonded Turn	trans	-70.6	16.2	-174.9	0	0	0	0	0	115.9	N66	N66-A68 VanDerWaalsContact C-N 3.34Å; N66-A68 PolarHBondContact O-N 3.01Å
69	W	47.6	Very low	35.8	Very low	209 Å²	209	134.1 Å²	134.1	79%	0.792	69%	0.693	S	S	*	*	T	Hydrogen-bonded Turn	trans	-125.3	-6.7	177.5	-65.8	99.1	0	0	0	114	D67	D67-W69 PolarHBondContact O-N 2.57Å
70	D	42	Very low	35.4	Very low	142 Å²	142	132.7 Å²	132.7	76%	0.759	70%	0.698	S	S	*	*			trans	-95.6	91.1	172.3	-72	-28.6	0	0	0	108.9	D67	D67-D70 PolarHBondContact O-N 3.36Å
71	I	33.7	Very low	34.7	Very low	148 Å²	148	131 Å²	131	76%	0.759	71%	0.71	S	S	*	*			trans	-128.7	95.4	162.7	-61.8	-177.8	0	0	0	107.8
72	D	36.8	Very low	34	Very low	141 Å²	141	130.3 Å²	130.3	75%	0.754	72%	0.718	S	S	*	*			trans	38.6	118.2	144	-47.6	-27.5	0	0	0	120.6
73	D	30.6	Very low	33.7	Very low	179 Å²	179	133.4 Å²	133.4	96%	0.957	73%	0.734	S	S	*	*			trans	-127.4	66.2	146.5	-92.2	-39.6	0	0	0	107.6
74	E	36.7	Very low	33.1	Very low	190 Å²	190	140 Å²	140	89%	0.888	76%	0.755	S	S	*	*			trans	-114.1	101.9	160.7	-82.5	-162	178.6	0	0	109.2
75	E	33.9	Very low	32.6	Very low	195 Å²	195	141.3 Å²	141.3	91%	0.911	76%	0.764	S	S	*	*			trans	-122.1	148.2	155.9	-78.5	-161.4	153	0	0	109.5
76	D	30.8	Very low	31.8	Very low	161 Å²	161	142.8 Å²	142.8	86%	0.861	78%	0.784	S	S	*	*			trans	-59.8	143.5	-169.6	-65.2	-76.5	0	0	0	114.8
77	D	28.7	Very low	31	Very low	165 Å²	165	143.6 Å²	143.6	88%	0.882	80%	0.797	S	S	*	*			trans	-147.8	121.6	137.6	-143.3	-17.8	0	0	0	111.4
78	N	26.6	Very low	30.4	Very low	153 Å²	153	147.8 Å²	147.8	82%	0.818	81%	0.81	S	S	*	*			trans	-149.1	75.9	-171.5	-169.9	6.2	0	0	0	111.9
79	F	23.2	Very low	30	Very low	201 Å²	201	150.4 Å²	150.4	88%	0.882	82%	0.818	S	S	*	*			trans	-140.7	160.5	169.8	-153.8	-105.1	0	0	0	113.9
80	C	27.4	Very low	29.4	Very low	113 Å²	113	145.3 Å²	145.3	76%	0.764	81%	0.812	S	S	*	*			trans	-91.3	146.9	-161.7	-175.1	0	0	0	0	114.2
81	G	24.5	Very low	28.6	Very low	74 Å²	74	143.6 Å²	143.6	76%	0.763	81%	0.812	S	S	*	*			trans	179.1	62.4	173.9	0	0	0	0	0	118.5
82	T	25.1	Very low	28.2	Very low	133 Å²	133	142.7 Å²	142.7	82%	0.816	81%	0.813	S	S	*	*			trans	-105.3	161.7	155.9	56	0	0	0	0	109.5
83	P	36.8	Very low	27.7	Very low	112 Å²	112	144.5 Å²	144.5	73%	0.727	82%	0.816	S	S	*	*			cis	-132.6	177.3	8.8	43.2	-28.5	0	0	0	115.3
84	F	24.6	Very low	27.6	Very low	206 Å²	206	143.6 Å²	143.6	90%	0.904	81%	0.81	S	S	*	*				-154.3	154.3	123.6	-128.5	-84.8	0	0	0	111.3
85	S	24.5	Very low	27.1	Very low	105 Å²	105	141.5 Å²	141.5	73%	0.734	81%	0.805	S	S	*	*			trans	-115.9	140.2	-174.7	51.7	0	0	0	0	112.8
86	A	25.2	Very low	26.7	Very low	105 Å²	105	140 Å²	140	87%	0.868	80%	0.802	S	S	*	*			trans	-150.9	110.8	160.1	0	0	0	0	0	109.6
87	S	23.7	Very low	26.4	Very low	100 Å²	100	139.3 Å²	139.3	70%	0.699	79%	0.794	S	S	*	*			trans	-88	149.1	177.3	52.1	0	0	0	0	111.9
88	F	23	Very low	26.3	Very low	201 Å²	201	137.9 Å²	137.9	88%	0.882	79%	0.786	S	S	*	*				-169.4	151.8	122.2	-99.3	-65.6	0	0	0	112
89	T	24.2	Very low	26.1	Very low	125 Å²	125	141.5 Å²	141.5	77%	0.767	79%	0.789	S	S	*	*			trans	-148.4	-172	-176.7	65.7	0	0	0	0	107.6
90	P	35.8	Very low	26.2	Very low	102 Å²	102	137.4 Å²	137.4	66%	0.662	78%	0.78	S	S	*	*			cis	-136.8	177.4	-8.7	39.1	-21.4	0	0	0	115.9
91	S	24.8	Very low	26.1	Very low	107 Å²	107	136.3 Å²	136.3	75%	0.748	77%	0.77	S	S	*	*			trans	67	163.8	150.5	64.7	0	0	0	0	117.5
92	V	26	Very low	26.2	Very low	129 Å²	129	139.8 Å²	139.8	78%	0.782	77%	0.771	S	S	*	*			cis	-145.2	152.9	32.5	165.3	0	0	0	0	111.9
93	Q	25.8	Very low	26.3	Very low	178 Å²	178	142.6 Å²	142.6	83%	0.832	78%	0.775	S	S	*	*			trans	-85.3	157.8	170.1	-62.1	167.6	-98.8	0	0	112.1
94	I	27.5	Very low	25.9	Very low	160 Å²	160	143.8 Å²	143.8	82%	0.821	78%	0.78	S	S	*	*			trans	172.7	137.3	130.4	-92.4	156.4	0	0	0	110.8
95	D	26.4	Very low	26.2	Very low	147 Å²	147	144.3 Å²	144.3	79%	0.786	78%	0.782	S	S	*	*			trans	-78.3	153	167.9	-57.6	-82.7	0	0	0	112
96	L	25.4	Very low	26.5	Very low	163 Å²	163	144.8 Å²	144.8	85%	0.853	79%	0.785	S	S	*	*			trans	178.2	110.3	139.7	-97.9	161.9	0	0	0	113.7
97	Q	24.4	Very low	26.6	Very low	146 Å²	146	146.8 Å²	146.8	68%	0.682	78%	0.781	S	S	*	*				51.9	110.2	122.6	-150.6	69.6	6.1	0	0	122.6
98	N	26.8	Very low	26.9	Very low	135 Å²	135	150.2 Å²	150.2	72%	0.722	79%	0.791	S	S	*	*			trans	72.1	152.6	143.2	-72.2	-6.8	0	0	0	123
99	W	23.3	Very low	27.4	Very low	230 Å²	230	149.6 Å²	149.6	87%	0.871	79%	0.791	S	S	*	*			trans	71.3	123.7	173.6	-129.8	64.1	0	0	0	113.6
100	V	24.4	Very low	27.6	Very low	114 Å²	114	148.8 Å²	148.8	69%	0.691	79%	0.79	S	S	*	*			cis	-127	152	40.8	167.9	0	0	0	0	112.9
101	T	26.6	Very low	27.3	Very low	91 Å²	91	153 Å²	153	56%	0.558	80%	0.798	S	S	*	*			trans	-104.5	177.5	173.1	58.9	0	0	0	0	112.9
102	N	25.2	Very low	27.6	Very low	146 Å²	146	158.8 Å²	158.8	78%	0.781	81%	0.805	S	S	*	*			trans	93.5	82.1	159.9	-46.2	-27.2	0	0	0	118.2
103	Q	27.7	Very low	27.7	Very low	193 Å²	193	162.3 Å²	162.3	90%	0.902	81%	0.81	S	S	*	*	S	Bend		-157.1	170.1	123.9	-110	172.3	20.5	0	0	110.3
104	V	29.6	Very low	27.8	Very low	137 Å²	137	159 Å²	159	83%	0.83	81%	0.806	S	S	*	*	S	Bend	trans	66.4	54.6	-179	-157.5	0	0	0	0	115.4
105	F	30.9	Very low	27.8	Very low	217 Å²	217	159 Å²	159	95%	0.952	81%	0.807	S	S	*	*			trans	-146.2	80.2	155.1	-116.7	-80.4	0	0	0	109.7
106	S	29	Very low	28	Very low	114 Å²	114	157.4 Å²	157.4	80%	0.797	81%	0.805	S	S	*	*			trans	-151.9	0.3	-176.2	-164.8	0	0	0	0	116.9
107	D	28.7	Very low	28.1	Very low	148 Å²	148	159.6 Å²	159.6	79%	0.791	81%	0.807	S	S	*	*	S	Bend	trans	-120.3	1.3	-166.2	-85.5	-57.8	0	0	0	116.8
108	L	29.9	Very low	28.1	Very low	171 Å²	171	159.5 Å²	159.5	90%	0.895	82%	0.817	S	S	*	*	S	Bend	trans	-110.9	-9.1	-173.5	-89.2	164.2	0	0	0	116.5
109	E	32.1	Very low	28	Very low	189 Å²	189	163.6 Å²	163.6	88%	0.883	82%	0.822	S	S	*	*	S	Bend	trans	-92.3	-3.5	-175.9	-140.8	-175.3	168.3	0	0	114.7	K111	E109-K111 PolarHBondContact O-N 3.45Å
110	S	29.1	Very low	28.1	Very low	108 Å²	108	160.7 Å²	160.7	76%	0.755	82%	0.824	S	S	*	*	S	Bend	trans	-83.8	-7.9	-171.2	63.5	0	0	0	0	115.7
111	K	30.8	Very low	28.2	Very low	190 Å²	190	163.3 Å²	163.3	83%	0.826	83%	0.826	S	S	*	*	S	Bend	trans	-111.3	9.6	-161.4	-132.6	172.2	-172.4	173.1	0	117.6	E109	E109-K111 PolarHBondContact O-N 3.45Å
112	Y	29.2	Very low	28.1	Very low	229 Å²	229	170.4 Å²	170.4	90%	0.898	84%	0.844	S	S	*	*	S	Bend	trans	-126.2	33.2	-175.9	-106.5	-76.2	0	0	0	115.9
113	K	29.6	Very low	28.1	Very low	202 Å²	202	173 Å²	173	88%	0.878	85%	0.849	S	S	*	*			trans	-135.3	58.4	176.2	-73.3	-177.4	-178.8	159.5	0	115.8
114	S	26.7	Very low	28	Very low	108 Å²	108	172 Å²	172	76%	0.755	85%	0.848	S	S	*	*			trans	-161.8	142.3	152.4	68.3	0	0	0	0	107.1
115	L	28.3	Very low	27.7	Very low	162 Å²	162	174.5 Å²	174.5	85%	0.848	85%	0.848	S	S	*	*			cis	-148.8	-167.6	48	-100.8	167.9	0	0	0	110.7
116	P	31	Very low	27.2	Very low	113 Å²	113	169.3 Å²	169.3	73%	0.734	84%	0.838	S	S	*	*			trans	-95	165.7	-137.1	39	-40.3	0	0	0	118
117	K	25.9	Very low	27	Very low	208 Å²	208	169.7 Å²	169.7	90%	0.904	84%	0.839	S	S	*	*			trans	-74.2	128.4	170.6	-60.1	168	-178.3	171.2	0	111.4
118	T	26.3	Very low	26.7	Very low	144 Å²	144	171 Å²	171	88%	0.883	84%	0.841	S	S	*	*			trans	-114	154.3	152	52.2	0	0	0	0	109.7
119	R	23.8	Very low	26.6	Very low	221 Å²	221	169.9 Å²	169.9	83%	0.834	84%	0.836	S	S	*	*			trans	-135	109.9	-159.9	-176.7	-169.4	-164.3	-178.4	7.7	110.5
120	N	25.3	Very low	26.2	Very low	169 Å²	169	168 Å²	168	90%	0.904	83%	0.832	S	S	*	*			trans	-128.4	145	164.7	-104.6	-31.4	0	0	0	111.1
121	K	26.1	Very low	26	Very low	170 Å²	170	169 Å²	169	74%	0.739	83%	0.833	S	S	*	*			trans	-105.5	132.6	-170.6	-59.5	169.7	-177.3	168.5	0	110.2
122	Y	25.9	Very low	25.7	Very low	239 Å²	239	167 Å²	167	94%	0.937	83%	0.831	S	S	*	*			trans	-130.4	139.9	148.5	-79.3	-75.5	0	0	0	109.8
123	K	24.2	Very low	25.5	Very low	201 Å²	201	161.4 Å²	161.4	87%	0.874	83%	0.825	S	S	*	*			trans	-93.8	134.8	179.6	-78.5	177.2	172	175.7	0	109.3
124	I	25.7	Very low	25.3	Very low	172 Å²	172	156.5 Å²	156.5	88%	0.882	82%	0.823	S	S	*	*			trans	-125	136.4	148.8	-61.8	-177.9	0	0	0	106.5
125	K	23	Very low	25.2	Very low	190 Å²	190	159.4 Å²	159.4	83%	0.826	83%	0.829	S	S	*	*			trans	-86.4	135.7	176.2	-72.4	-179.6	174.6	-178.9	0	109.3
126	S	21.4	Very low	25.1	Very low	107 Å²	107	156.4 Å²	156.4	75%	0.748	83%	0.827	S	S	*	*			trans	-83.8	148.5	153.5	49.6	0	0	0	0	109.8
127	C	24.1	Very low	24.7	Very low	123 Å²	123	154.3 Å²	154.3	83%	0.831	83%	0.826	S	S	*	*			trans	-131.4	114	163.8	-73.5	0	0	0	0	108.2
128	Q	23.2	Very low	24.7	Very low	176 Å²	176	149.8 Å²	149.8	82%	0.822	83%	0.828	S	S	*	*			trans	-93.3	144.7	164.4	-66	165.8	-74.9	0	0	108.6
129	N	26.1	Very low	24.5	Very low	147 Å²	147	148.6 Å²	148.6	79%	0.786	83%	0.825	S	S	*	*			trans	-156.4	113.8	149.9	-91.7	-37.5	0	0	0	105.2
130	N	24.6	Very low	24.7	Very low	150 Å²	150	142.8 Å²	142.8	80%	0.802	83%	0.825	S	S	*	*				77.2	134.3	74.3	-81	-18.5	0	0	0	113
131	V	24.9	Very low	24.7	Very low	128 Å²	128	142.4 Å²	142.4	78%	0.776	82%	0.815	S	S	*	*			trans	-116.2	141.2	-169.6	-169.3	0	0	0	0	108.3
132	N	24.9	Very low	24.6	Very low	148 Å²	148	143.3 Å²	143.3	79%	0.791	82%	0.815	S	S	*	*				168.1	136.2	129.8	-85.4	-22.5	0	0	0	115.7
133	S	25	Very low	24.6	Very low	111 Å²	111	140.1 Å²	140.1	78%	0.776	81%	0.808	S	S	*	*			trans	39.6	116.6	142.1	66.6	0	0	0	0	123.1
134	A	25.4	Very low	24.7	Very low	99 Å²	99	136.7 Å²	136.7	82%	0.818	80%	0.804	S	S	*	*				176.8	134.1	118.8	0	0	0	0	0	108.1
135	L	24.8	Very low	24.7	Very low	169 Å²	169	132.1 Å²	132.1	89%	0.885	80%	0.799	S	S	*	*			cis	110	133.4	25.8	-165.3	149.2	0	0	0	111
136	A	25.4	Very low	24.9	Very low	99 Å²	99	128.5 Å²	128.5	82%	0.818	79%	0.793	S	S	*	*			trans	68.3	149.6	-165.2	0	0	0	0	0	115.2
137	G	23.2	Very low	25.6	Very low	69 Å²	69	129.5 Å²	129.5	71%	0.711	80%	0.797	S	S	*	*			cis	172.8	-175.8	-6.5	0	0	0	0	0	113.4
138	A	25.8	Very low	25.8	Very low	114 Å²	114	130.3 Å²	130.3	94%	0.942	79%	0.792	S	S	*	*			trans	72.6	145.1	175	0	0	0	0	0	118.6
139	S	22.3	Very low	25.9	Very low	118 Å²	118	129.2 Å²	129.2	83%	0.825	79%	0.792	S	S	*	*			trans	-116	146.2	-177.4	169.6	0	0	0	0	110.3
140	A	27.1	Very low	26	Very low	100 Å²	100	128.2 Å²	128.2	83%	0.826	79%	0.791	S	S	*	*			trans	-150	142.1	160.7	0	0	0	0	0	110.9
141	K	25.4	Very low	26	Very low	161 Å²	161	124.3 Å²	124.3	70%	0.7	79%	0.786	S	S	*	*			trans	-100.1	159.4	168.6	-60.7	169.3	-177.3	173.8	0	108.5
142	Y	24.6	Very low	26.2	Very low	188 Å²	188	127.1 Å²	127.1	74%	0.737	79%	0.788	S	S	*	*				157.3	152.3	110.7	-90.8	-68.7	0	0	0	115.8
143	H	25.1	Very low	26.2	Very low	172 Å²	172	125.5 Å²	125.5	80%	0.796	78%	0.783	S	S	*	*			trans	74.1	112.7	152.2	-81	-65.5	0	0	0	124.1
144	V	27.1	Very low	26.2	Very low	130 Å²	130	125.8 Å²	125.8	79%	0.788	78%	0.776	S	S	*	*			trans	-49.7	148.9	154.5	175	0	0	0	0	113.6	V146	V144-V146 HydrophobicContact CG1-CG2 4.42Å
145	G	24.8	Very low	26.1	Very low	75 Å²	75	129.2 Å²	129.2	77%	0.773	77%	0.773	S	S	*	*			trans	-156	121.4	159	0	0	0	0	0	112.4
146	V	28.4	Very low	26.1	Very low	114 Å²	114	128.6 Å²	128.6	69%	0.691	77%	0.77	S	S	*	*			trans	-121.8	147.9	173.3	-166.3	0	0	0	0	107.6	V144 L148	V144-V146 HydrophobicContact CG1-CG2 4.42Å; V146-L148 HydrophobicContact CG1-CD1 4.47Å
147	P	36.3	Very low	26.1	Very low	128 Å²	128	128.8 Å²	128.8	83%	0.831	77%	0.765	S	S	*	*				-142.3	161.3	121.6	32.7	-16.8	0	0	0	114.6
148	L	27.4	Very low	26.1	Very low	140 Å²	140	130.6 Å²	130.6	73%	0.733	77%	0.767	S	S	*	*			trans	-102.2	153.3	170	-68.4	107.4	0	0	0	111.6	V146	V146-L148 HydrophobicContact CG1-CD1 4.47Å
149	N	25.9	Very low	26	Very low	154 Å²	154	130.7 Å²	130.7	82%	0.824	76%	0.761	S	S	*	*				-177.2	137.8	129	-88.9	-31.5	0	0	0	108.3
150	V	27.2	Very low	26.2	Very low	126 Å²	126	129.7 Å²	129.7	76%	0.764	76%	0.76	S	S	*	*			cis	100.8	112	26.5	173.4	0	0	0	0	113.4
151	G	25.7	Very low	26	Very low	68 Å²	68	132.1 Å²	132.1	70%	0.701	76%	0.758	S	S	*	*			trans	117.1	150.6	161.3	0	0	0	0	0	116
152	K	27.5	Very low	26.2	Very low	187 Å²	187	130.6 Å²	130.6	81%	0.813	77%	0.765	S	S	*	*			cis	-174	141.5	-18.2	-127.4	-177.6	-178.7	178.4	0	109.7
153	T	24.8	Very low	26.2	Very low	114 Å²	114	126.3 Å²	126.3	70%	0.699	76%	0.761	S	S	*	*			trans	61.2	158.4	153	55.5	0	0	0	0	120.1
154	N	25.6	Very low	26.1	Very low	117 Å²	117	127.3 Å²	127.3	63%	0.626	76%	0.764	S	S	*	*			cis	-169.1	174.5	-20	-101.8	3.6	0	0	0	110.9
155	F	24.4	Very low	25.9	Very low	170 Å²	170	129.4 Å²	129.4	75%	0.746	77%	0.77	S	S	*	*			trans	79.9	123.3	156.7	-58.6	-52.3	0	0	0	118.4
156	L	25.1	Very low	25.9	Very low	157 Å²	157	131 Å²	131	82%	0.822	77%	0.769	S	S	*	*				63	138.7	93.8	-62.3	173.5	0	0	0	114
157	S	24.4	Very low	25.7	Very low	103 Å²	103	131.1 Å²	131.1	72%	0.72	78%	0.775	S	S	*	*			cis	-159.6	-160.4	-4.5	54.8	0	0	0	0	108.5
158	S	23.2	Very low	25.5	Very low	106 Å²	106	131.2 Å²	131.2	74%	0.741	77%	0.773	S	S	*	*			cis	-161.9	-178.8	8.7	26.1	0	0	0	0	111.8
159	S	23.6	Very low	25.3	Very low	117 Å²	117	135.6 Å²	135.6	82%	0.818	78%	0.78	S	S	*	*			trans	-56.9	153.6	176.9	54	0	0	0	0	119.5
160	A	25.6	Very low	25.3	Very low	97 Å²	97	133.3 Å²	133.3	80%	0.802	78%	0.776	S	S	*	*				-173.6	142.8	118.7	0	0	0	0	0	113.8
161	N	24.8	Very low	25.2	Very low	150 Å²	150	131.9 Å²	131.9	80%	0.802	77%	0.771	S	S	*	*			trans	-116.2	157	160.8	-89.8	-15.4	0	0	0	108.7
162	P	28.8	Very low	25.4	Very low	130 Å²	130	137 Å²	137	84%	0.844	78%	0.782	S	S	*	*				-137.4	170.6	119.5	36.8	-25.4	0	0	0	113.9
163	C	23.9	Very low	25.6	Very low	97 Å²	97	135.9 Å²	135.9	66%	0.655	78%	0.78	S	S	*	*			trans	-112.2	172.6	-165.7	-63.5	0	0	0	0	115
164	F	22.6	Very low	25.9	Very low	194 Å²	194	138.8 Å²	138.8	85%	0.851	78%	0.782	S	S	*	*			trans	76.2	112.9	162.1	-60.8	-74.9	0	0	0	119.6
165	L	24.6	Very low	26.1	Very low	173 Å²	173	142.2 Å²	142.2	91%	0.906	80%	0.795	S	S	*	*				-149.7	173.3	90.1	-133.5	84.6	0	0	0	111.1
166	S	24.4	Very low	26.5	Very low	108 Å²	108	143 Å²	143	76%	0.755	80%	0.801	S	S	*	*			trans	-106.4	145	-165.8	52.4	0	0	0	0	115
167	S	24.1	Very low	26.8	Very low	118 Å²	118	140.7 Å²	140.7	83%	0.825	80%	0.797	S	S	*	*			trans	-156.1	126.6	151.2	-158.7	0	0	0	0	110.6
168	V	31	Very low	27.2	Very low	129 Å²	129	143.2 Å²	143.2	78%	0.782	80%	0.802	S	S	*	*			trans	-92	116.5	-177	177.2	0	0	0	0	110.4
169	R	25	Very low	27.4	Very low	232 Å²	232	143.5 Å²	143.5	88%	0.875	80%	0.801	S	S	*	*			trans	-139	93.3	160.9	-75.7	-168.7	173.1	-177.2	-1.3	110.3	S171	R169-S171 VanDerWaalsContact C-N 3.3Å; R169-S171 PolarHBondContact O-N 3.29Å
170	S	25.8	Very low	28	Very low	107 Å²	107	141.6 Å²	141.6	75%	0.748	79%	0.785	S	S	*	*			trans	-72.7	79.5	173.3	40.4	0	0	0	0	111.2	L172	S170-L172 PolarHBondContact O-N 2.86Å; S170-L172 VanDerWaalsContact O-N 3.09Å
171	S	24.8	Very low	28.4	Very low	95 Å²	95	146.5 Å²	146.5	66%	0.664	78%	0.782	S	S	*	*			trans	-67.8	104.4	166.4	55.5	0	0	0	0	109.5	R169 Q173	R169-S171 VanDerWaalsContact C-N 3.3Å; R169-S171 PolarHBondContact O-N 3.29Å; S171-Q173 VanDerWaalsContact C-N 3.28Å; S171-Q173 PolarHBondContact O-N 2.95Å
172	L	29.2	Very low	28.8	Very low	176 Å²	176	145.2 Å²	145.2	92%	0.921	78%	0.782	S	S	*	*			trans	-63.5	88.9	170.4	-78.6	165.9	0	0	0	109.6	S170	S170-L172 PolarHBondContact O-N 2.86Å; S170-L172 VanDerWaalsContact O-N 3.09Å
173	Q	31.7	Very low	29.5	Very low	164 Å²	164	142.4 Å²	142.4	77%	0.766	76%	0.759	S	S	*	*			trans	-68.7	136.7	169.3	-74.4	-174.8	-20.4	0	0	109.1	S171 Q175	S171-Q173 VanDerWaalsContact C-N 3.28Å; S171-Q173 PolarHBondContact O-N 2.95Å; Q173-Q175 PolarHBondContact O-N 2.81Å
174	K	30.4	Very low	30.2	Very low	174 Å²	174	143.2 Å²	143.2	76%	0.757	76%	0.756	S	S	*	*			trans	-60.9	98.4	177.6	-166.5	-178.9	-171.1	-175.2	0	108.3	Q176	K174-Q176 PolarHBondContact O-N 2.83Å; K174-Q176 VanDerWaalsContact O-N 3.13Å
175	Q	31	Very low	31.3	Very low	190 Å²	190	134.7 Å²	134.7	89%	0.888	72%	0.72	S	S	*	*	P	Polyproline II helix	trans	-56.7	120.6	-177	-79.1	-175.6	-44.4	0	0	109.5	Q173	Q173-Q175 PolarHBondContact O-N 2.81Å
176	Q	31.8	Very low	32.2	Very low	186 Å²	186	132.5 Å²	132.5	87%	0.869	71%	0.709	S	S	*	*	P	Polyproline II helix	trans	-70.7	145	169.4	-69.4	176.4	-34.7	0	0	108.2	K174	K174-Q176 PolarHBondContact O-N 2.83Å; K174-Q176 VanDerWaalsContact O-N 3.13Å
177	S	31.9	Very low	33.6	Very low	108 Å²	108	128.3 Å²	128.3	76%	0.755	68%	0.679	S	S	*	*	P	Polyproline II helix	trans	-57.1	141.2	178.9	34	0	0	0	0	111.1
178	L	32.8	Very low	34.9	Very low	157 Å²	157	123.5 Å²	123.5	82%	0.822	65%	0.646	S	S	*	*	P	Polyproline II helix	trans	-56.3	142.2	173.7	-71.6	169.9	0	0	0	109.8	V180	L178-V180 PolarHBondContact O-N 2.98Å; L178-V180 VanDerWaalsContact O-N 3.12Å
179	P	27.9	Very low	36.2	Very low	111 Å²	111	122 Å²	122	72%	0.721	63%	0.626	S	S	*	*	P	Polyproline II helix	trans	-62	119.2	-176.1	24.6	-33.8	0	0	0	110.5	R181	P179-R181 PolarHBondContact O-N 3.46Å
180	V	36.8	Very low	37.9	Very low	77 Å²	77	112 Å²	112	47%	0.467	59%	0.59	S	S	.	*			trans	-62.7	95.9	179.4	-178.2	0	0	0	0	109.3	L178	L178-V180 PolarHBondContact O-N 2.98Å; L178-V180 VanDerWaalsContact O-N 3.12Å
181	R	33.7	Very low	39.3	Very low	200 Å²	200	109 Å²	109	76%	0.755	57%	0.569	S	S	*	*			trans	-62.1	141.8	167.2	-67.5	-175.1	178	-174.7	0	108.6	P179 I183	P179-R181 PolarHBondContact O-N 3.46Å; R181-I183 HydrophobicContact CB-CG1 4.48Å; R181-I183 PolarHBondContact O-N 3.39Å
182	P	32.4	Very low	40.6	Very low	124 Å²	124	107.8 Å²	107.8	81%	0.805	56%	0.555	S	S	*	*			trans	-72.5	80.2	174.8	30.8	-34.7	0	0	0	109.9	I184	P182-I184 PolarHBondContact O-N 3.28Å; P182-I184 VanDerWaalsContact O-N 3.1Å
183	I	42.8	Very low	41.1	Very low	70 Å²	70	105.6 Å²	105.6	36%	0.359	54%	0.54	S	S	.	.			trans	-74	99	170.4	-60.1	179.7	0	0	0	106.6	R181 P185 R434	R181-I183 HydrophobicContact CB-CG1 4.48Å; R181-I183 PolarHBondContact O-N 3.39Å; I183-P185 WeakPolarHBondContact O-CD 3.46Å; I183-R434 VanDerWaalsContact CD1-NH1 3.28Å
184	I	39.8	Very low	41.4	Very low	115 Å²	115	102.1 Å²	102.1	59%	0.59	53%	0.527	S	S	*	.			trans	-62.3	115.4	171.6	-60.8	172	0	0	0	106.8	P182 L186 L304	P182-I184 PolarHBondContact O-N 3.28Å; P182-I184 VanDerWaalsContact O-N 3.1Å; I184-L186 PolarHBondContact O-N 2.83Å; I184-L304 HydrophobicContact CG2-CD1 3.98Å; I184-L304 HydrophobicContact CG2-CD2 4.29Å; I184-L304 HydrophobicContact CG2-CG 4.42Å
185	P	44.5	Very low	41.6	Very low	14 Å²	14	97.7 Å²	97.7	9%	0.091	52%	0.523	C	S	.	.			trans	-72.8	97.5	180	-13.6	30.2	0	0	0	108.6	I183 V187 A188 L304	I183-P185 WeakPolarHBondContact O-CD 3.46Å; P185-V187 PolarHBondContact O-N 3.47Å; P185-A188 PolarHBondContact O-N 3.1Å; P185-L304 WeakPolarHBondContact O-CD1 3.15Å
186	L	45	Very low	41.8	Very low	127 Å²	127	94.6 Å²	94.6	67%	0.665	52%	0.522	S	S	*	.	T	Hydrogen-bonded Turn	trans	-64	16.2	178.1	-114.5	166.6	0	0	0	114.1	I184 I501	I184-L186 PolarHBondContact O-N 2.83Å; L186-I501 HydrophobicContact CD2-CD1 4.5Å; L186-I501 WeakPolarHBondContact O-CD1 3.47Å; L186-I501 VanDerWaalsContact O-CG1 3.27Å; L186-I501 WeakPolarHBondContact O-CG1 3.37Å
187	V	52.8	Low	42.1	Very low	21 Å²	21	89.1 Å²	89.1	13%	0.127	52%	0.516	C	S	.	.	T	Hydrogen-bonded Turn	trans	-133	-9.6	-158.8	-152.6	0	0	0	0	111	P185 R189 L444 P445	P185-V187 PolarHBondContact O-N 3.47Å; V187-R189 PolarHBondContact O-N 3.12Å; V187-L444 VanDerWaalsContact CG1-C 3.41Å; V187-P445 HydrophobicContact CG1-CB 4.3Å; V187-P445 VanDerWaalsContact CG1-CD 3.43Å; V187-P445 HydrophobicContact CG1-CG 3.69Å; V187-P445 VanDerWaalsContact CG1-N 3.3Å; V187-P445 WeakPolarHBondContact O-CA 3.33Å
188	A	51	Low	42.7	Very low	17 Å²	17	87.1 Å²	87.1	14%	0.14	51%	0.506	C	S	.	.			trans	-75	85.4	-173.5	0	0	0	0	0	112.8	P185 L304 I305	P185-A188 PolarHBondContact O-N 3.1Å; A188-L304 HydrophobicContact CB-CB 4.26Å; A188-I305 HydrophobicContact CB-CD1 3.79Å; A188-I305 HydrophobicContact CB-CG1 3.98Å; A188-I305 WeakPolarHBondContact O-CG1 3.46Å
189	R	58.9	Low	43.5	Very low	97 Å²	97	84.3 Å²	84.3	37%	0.366	50%	0.497	S	S	.	.			trans	-134.9	140.1	162.8	-70.6	179.2	179.5	173.2	-7.5	109.6	V187 L446	V187-R189 PolarHBondContact O-N 3.12Å; R189-L446 PolarHBondContact O-N 3.46Å
190	I	61.4	Low	45	Very low	21 Å²	21	84.9 Å²	84.9	11%	0.108	50%	0.501	C	S	.	.			trans	-95.9	-34.5	178.5	-50.1	-169.9	0	0	0	110.5	I305 L307 F308 V346 E358 L446 R447	I190-I305 HydrophobicContact CD1-CD1 4.23Å; I190-I305 HydrophobicContact CD1-CG2 3.86Å; I190-I305 HydrophobicContact CG1-CD1 3.73Å; I190-I305 HydrophobicContact CG1-CG1 4.44Å; I190-I305 HydrophobicContact CG1-CG2 4.26Å; I190-L307 HydrophobicContact CD1-CD2 4.33Å; I190-F308 HydrophobicContact CD1-CE2 4.27Å; I190-F308 HydrophobicContact CD1-CZ 4.35Å; I190-V346 HydrophobicContact CD1-CG1 4.15Å; I190-V346 HydrophobicContact CD1-CG2 3.73Å; I190-V346 HydrophobicContact CG2-CG1 3.5Å; I190-E358 HydrophobicContact CB-CG 3.57Å; I190-E358 HydrophobicContact CD1-CG 3.99Å; I190-E358 HydrophobicContact CG1-CG 3.69Å; I190-E358 VanDerWaalsContact N-CD 3.33Å; I190-E358 PolarHBondContact N-OE1 3.01Å; I190-L446 HydrophobicContact CD1-CD2 3.81Å; I190-L446 HydrophobicContact CG1-CB 4.33Å; I190-L446 HydrophobicContact CG1-CD2 3.78Å; I190-R447 WeakPolarHBondContact O-CB 3.13Å
191	S	55.8	Low	46.6	Very low	46 Å²	46	85.6 Å²	85.6	32%	0.322	50%	0.5	S	S	.	.	S	Bend	trans	-79.1	147.8	177.7	55.9	0	0	0	0	112.1	E358 R447	S191-E358 VanDerWaalsContact CB-OE1 3.31Å; S191-E358 WeakPolarHBondContact CB-OE1 3.43Å; S191-E358 PolarHBondContact N-OE1 3.13Å; S191-E358 PolarHBondContact OG-OE1 3.08Å; S191-R447 PolarHBondContact O-NH1 3.02Å
192	D	50.3	Low	48.8	Very low	69 Å²	69	79.5 Å²	79.5	37%	0.369	49%	0.485	S	S	.	.			trans	-69.3	148.7	149.6	-63.9	-59.4	0	0	0	108.2	N194 R447	D192-N194 PolarHBondContact O-N 3.03Å; D192-R447 WeakPolarHBondContact OD1-CD 3.41Å; D192-R447 IonicContact OD1-NE 2.68Å
193	Q	40.1	Very low	51.1	Low	129 Å²	129	79.9 Å²	79.9	60%	0.603	49%	0.485	S	S	*	.	T	Hydrogen-bonded Turn	trans	-71.2	21.8	-177.7	-71.5	178.5	108.6	0	0	114.4
194	N	37.9	Very low	52.9	Low	91 Å²	91	85.4 Å²	85.4	49%	0.487	50%	0.501	S	S	.	.	T	Hydrogen-bonded Turn	trans	-107	11.7	-176.6	-67.3	-12.1	0	0	0	112.7	D192 S196 A198	D192-N194 PolarHBondContact O-N 3.03Å; N194-S196 PolarHBondContact O-N 3.32Å; N194-A198 HydrophobicContact CB-CB 4.07Å; N194-A198 WeakPolarHBondContact O-CA 3.48Å; N194-A198 WeakPolarHBondContact O-CB 3.35Å; N194-A198 PolarHBondContact O-N 2.94Å
195	A	36.2	Very low	55	Low	81 Å²	81	84.7 Å²	84.7	67%	0.669	50%	0.495	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.7	9.5	174.9	0	0	0	0	0	114.7
196	S	33.9	Very low	57.1	Low	125 Å²	125	89.9 Å²	89.9	87%	0.874	52%	0.517	S	S	*	.	T	Hydrogen-bonded Turn	trans	-147.1	78.8	168.9	-67.5	0	0	0	0	108.7	N194	N194-S196 PolarHBondContact O-N 3.32Å
197	G	38.3	Very low	59.3	Low	72 Å²	72	86.9 Å²	86.9	74%	0.742	51%	0.506	S	S	*	.	T	Hydrogen-bonded Turn	trans	111.6	28.3	-179.4	0	0	0	0	0	116
198	A	45.1	Very low	61.1	Low	65 Å²	65	89.5 Å²	89.5	54%	0.537	51%	0.514	S	S	.	.	P	Polyproline II helix	trans	-49.6	132.4	167.2	0	0	0	0	0	110.8	N194	N194-A198 HydrophobicContact CB-CB 4.07Å; N194-A198 WeakPolarHBondContact O-CA 3.48Å; N194-A198 WeakPolarHBondContact O-CB 3.35Å; N194-A198 PolarHBondContact O-N 2.94Å
199	P	50	Low	63.2	Low	98 Å²	98	89.2 Å²	89.2	64%	0.636	51%	0.509	S	S	*	.	P	Polyproline II helix	trans	-55.1	144.3	175.7	-26.1	34.9	0	0	0	111.3	M201	P199-M201 PolarHBondContact O-N 3.15Å
200	P	58.7	Low	64.8	Low	123 Å²	123	87.1 Å²	87.1	80%	0.799	51%	0.506	S	S	*	.	P	Polyproline II helix	trans	-57.8	134	171.5	25.9	-33.9	0	0	0	109.3	T202	P200-T202 PolarHBondContact O-N 3.4Å
201	M	69.2	Low	66.2	Low	93 Å²	93	91.2 Å²	91.2	46%	0.458	52%	0.523	S	S	.	.			trans	-43.3	128.4	-174.7	-69.7	-178.3	73.7	0	0	111.9	P199 E205 L209	P199-M201 PolarHBondContact O-N 3.15Å; M201-E205 HydrophobicContact CE-CB 4.07Å; M201-L209 HydrophobicContact CE-CB 4.42Å; M201-L209 HydrophobicContact CE-CD2 3.95Å
202	T	80.6	Confident	68.1	Low	72 Å²	72	89.1 Å²	89.1	44%	0.442	51%	0.508	S	S	.	.			trans	-63.8	155.7	176.7	65.6	0	0	0	0	110.8	P200 R204 E205 K206	P200-T202 PolarHBondContact O-N 3.4Å; T202-R204 PolarHBondContact O-N 2.8Å; T202-R204 VanDerWaalsContact O-N 3.16Å; T202-E205 VanDerWaalsContact CB-OE2 3.26Å; T202-E205 WeakPolarHBondContact CB-OE2 3.19Å; T202-E205 VanDerWaalsContact CG2-OE2 3.31Å; T202-E205 WeakPolarHBondContact CG2-OE2 3.21Å; T202-E205 PolarHBondContact N-OE2 3.08Å; T202-E205 PolarHBondContact O-N 3.36Å; T202-E205 VanDerWaalsContact O-N 3.08Å; T202-E205 VanDerWaalsContact OG1-CD 3.31Å; T202-E205 VanDerWaalsContact OG1-CG 3.31Å; T202-E205 WeakPolarHBondContact OG1-CG 3.47Å; T202-E205 PolarHBondContact OG1-N 2.92Å; T202-E205 PolarHBondContact OG1-OE2 2.96Å; T202-K206 PolarHBondContact O-N 2.9Å
203	V	80.6	Confident	70.1	Confident	132 Å²	132	90.4 Å²	90.4	80%	0.8	51%	0.51	S	S	*	.	H	α-helix	trans	-56.1	-33.6	175.2	-176.5	0	0	0	0	111.2	S207	V203-S207 VanDerWaalsContact O-CB 3.27Å; V203-S207 WeakPolarHBondContact O-CB 3.42Å; V203-S207 PolarHBondContact O-N 2.97Å
204	R	81.9	Confident	72.5	Confident	186 Å²	186	90.8 Å²	90.8	70%	0.702	51%	0.512	S	S	*	.	H	α-helix	trans	-66.6	-44.8	176.2	-164.2	179.1	-167.5	-175.9	6.1	112	N66 T202 R208	N66-R204 PolarHBondContact OD1-NH2 3.48Å; T202-R204 PolarHBondContact O-N 2.8Å; T202-R204 VanDerWaalsContact O-N 3.16Å; R204-R208 WeakPolarHBondContact O-CB 3.25Å; R204-R208 PolarHBondContact O-N 3.4Å
205	E	83.4	Confident	75	Confident	99 Å²	99	88.3 Å²	88.3	46%	0.463	50%	0.498	S	S	.	.	H	α-helix	trans	-68	-40.6	177.4	-70.7	160.9	124.9	0	0	112.1	M201 T202 R208 L209	M201-E205 HydrophobicContact CE-CB 4.07Å; T202-E205 VanDerWaalsContact CB-OE2 3.26Å; T202-E205 WeakPolarHBondContact CB-OE2 3.19Å; T202-E205 VanDerWaalsContact CG2-OE2 3.31Å; T202-E205 WeakPolarHBondContact CG2-OE2 3.21Å; T202-E205 PolarHBondContact N-OE2 3.08Å; T202-E205 PolarHBondContact O-N 3.36Å; T202-E205 VanDerWaalsContact O-N 3.08Å; T202-E205 VanDerWaalsContact OG1-CD 3.31Å; T202-E205 VanDerWaalsContact OG1-CG 3.31Å; T202-E205 WeakPolarHBondContact OG1-CG 3.47Å; T202-E205 PolarHBondContact OG1-N 2.92Å; T202-E205 PolarHBondContact OG1-OE2 2.96Å; E205-R208 WeakPolarHBondContact O-CB 3.36Å; E205-R208 PolarHBondContact O-N 3.25Å; E205-L209 WeakPolarHBondContact O-CB 3.48Å; E205-L209 PolarHBondContact O-N 3.28Å
206	K	88.2	Confident	77.5	Confident	124 Å²	124	85.2 Å²	85.2	54%	0.539	47%	0.47	S	S	.	.	H	α-helix	trans	-62.7	-47.9	175.1	-174.1	176.6	178.2	-177.5	0	111.4	T202 R208 L209 D210	T202-K206 PolarHBondContact O-N 2.9Å; K206-R208 VanDerWaalsContact C-N 3.31Å; K206-R208 PolarHBondContact O-N 2.74Å; K206-L209 PolarHBondContact O-N 3.19Å; K206-D210 PolarHBondContact O-N 2.83Å
207	S	90.9	Very high	80.1	Confident	63 Å²	63	81.7 Å²	81.7	44%	0.441	45%	0.449	S	S	.	.	H	α-helix	trans	-57.9	-42.2	174.4	-179.5	0	0	0	0	112	V203 D210 K211	V203-S207 VanDerWaalsContact O-CB 3.27Å; V203-S207 WeakPolarHBondContact O-CB 3.42Å; V203-S207 PolarHBondContact O-N 2.97Å; S207-D210 PolarHBondContact O-N 3.13Å; S207-K211 WeakPolarHBondContact O-CG 3.4Å; S207-K211 PolarHBondContact O-N 3.12Å
208	R	91.6	Very high	82.1	Confident	77 Å²	77	79.4 Å²	79.4	29%	0.291	42%	0.422	S	S	.	.	H	α-helix	trans	-59.7	-50.8	173.9	-171.2	-177.4	-170.8	92	9.4	111.6	R204 E205 K206 D210 K211 F212 H232 S235 G236 P238	R204-R208 WeakPolarHBondContact O-CB 3.25Å; R204-R208 PolarHBondContact O-N 3.4Å; E205-R208 WeakPolarHBondContact O-CB 3.36Å; E205-R208 PolarHBondContact O-N 3.25Å; K206-R208 VanDerWaalsContact C-N 3.31Å; K206-R208 PolarHBondContact O-N 2.74Å; R208-D210 VanDerWaalsContact C-N 3.33Å; R208-D210 PolarHBondContact O-N 2.92Å; R208-K211 PolarHBondContact O-N 2.81Å; R208-F212 HydrophobicContact CG-CD2 4.24Å; R208-F212 HydrophobicContact CG-CE2 4.18Å; R208-F212 WeakPolarHBondContact O-CD2 3.35Å; R208-F212 PolarHBondContact O-N 3.3Å; R208-H232 PolarHBondContact NH2-O 2.68Å; R208-S235 PolarHBondContact NH1-OG 3.43Å; R208-S235 PolarHBondContact NH2-O 2.87Å; R208-S235 PolarHBondContact NH2-OG 3.17Å; R208-G236 VanDerWaalsContact CZ-O 3.31Å; R208-G236 PolarHBondContact NE-O 3Å; R208-G236 VanDerWaalsContact NE-O 3.12Å; R208-G236 PolarHBondContact NH2-O 3.19Å; R208-P238 HydrophobicContact CG-CG 4.17Å
209	L	93.5	Very high	83.4	Confident	10 Å²	10	82 Å²	82	5%	0.052	43%	0.433	C	S	.	.	H	α-helix	trans	-59.4	-42.4	178.4	172.5	60.1	0	0	0	111.9	M201 E205 K206 F212 K213 P238 E240 V241	M201-L209 HydrophobicContact CE-CB 4.42Å; M201-L209 HydrophobicContact CE-CD2 3.95Å; E205-L209 WeakPolarHBondContact O-CB 3.48Å; E205-L209 PolarHBondContact O-N 3.28Å; K206-L209 PolarHBondContact O-N 3.19Å; L209-F212 WeakPolarHBondContact O-CB 3.21Å; L209-F212 PolarHBondContact O-N 3.09Å; L209-K213 HydrophobicContact CD1-CG 4.44Å; L209-K213 HydrophobicContact CG-CD 4.48Å; L209-K213 WeakPolarHBondContact O-CG 3.33Å; L209-K213 PolarHBondContact O-N 3.07Å; L209-P238 HydrophobicContact CB-CB 4.31Å; L209-P238 HydrophobicContact CB-CG 4.3Å; L209-P238 HydrophobicContact CD1-CB 4.07Å; L209-E240 HydrophobicContact CD1-CB 4.03Å; L209-E240 HydrophobicContact CD1-CG 4.4Å; L209-E240 HydrophobicContact CD2-CG 4.17Å; L209-V241 HydrophobicContact CD1-CG1 3.8Å; L209-V241 HydrophobicContact CD1-CG2 4.06Å
210	D	93.4	Very high	83.9	Confident	54 Å²	54	82.1 Å²	82.1	29%	0.289	43%	0.428	S	S	.	.	H	α-helix	trans	-71.1	-34.4	-179	-66.3	-25.6	0	0	0	112	K206 S207 R208 K213 Q214	K206-D210 PolarHBondContact O-N 2.83Å; S207-D210 PolarHBondContact O-N 3.13Å; R208-D210 VanDerWaalsContact C-N 3.33Å; R208-D210 PolarHBondContact O-N 2.92Å; D210-K213 PolarHBondContact O-N 3.42Å; D210-K213 IonicContact OD1-NZ 3.56Å; D210-K213 PolarHBondContact OD1-NZ 2.79Å; D210-Q214 WeakPolarHBondContact O-CG 3.38Å; D210-Q214 PolarHBondContact O-N 3.19Å
211	K	91.6	Very high	83.8	Confident	107 Å²	107	81.7 Å²	81.7	47%	0.465	42%	0.423	S	S	.	.	H	α-helix	trans	-60.1	-44.3	167.3	-73.2	-176.3	-178.9	-167.3	0	112.2	S207 R208 K213 Q214 L215	S207-K211 WeakPolarHBondContact O-CG 3.4Å; S207-K211 PolarHBondContact O-N 3.12Å; R208-K211 PolarHBondContact O-N 2.81Å; K211-K213 PolarHBondContact O-N 2.86Å; K211-Q214 PolarHBondContact O-N 2.74Å; K211-L215 WeakPolarHBondContact O-CG 3.35Å; K211-L215 PolarHBondContact O-N 2.68Å; K211-L215 VanDerWaalsContact O-N 3.1Å
212	F	94.3	Very high	83.7	Confident	1 Å²	1	80 Å²	80	0%	0.004	42%	0.416	C	S	.	.	H	α-helix	trans	-61	-44.2	174.2	-91.6	-89	0	0	0	112.3	R208 L209 Q214 L215 L216 L229 H232 I237 P238 V241 T245	R208-F212 HydrophobicContact CG-CD2 4.24Å; R208-F212 HydrophobicContact CG-CE2 4.18Å; R208-F212 WeakPolarHBondContact O-CD2 3.35Å; R208-F212 PolarHBondContact O-N 3.3Å; L209-F212 WeakPolarHBondContact O-CB 3.21Å; L209-F212 PolarHBondContact O-N 3.09Å; F212-Q214 VanDerWaalsContact C-N 3.33Å; F212-Q214 PolarHBondContact O-N 2.94Å; F212-L215 PolarHBondContact O-N 3.32Å; F212-L216 WeakPolarHBondContact O-CB 3.34Å; F212-L216 WeakPolarHBondContact O-CD1 3.45Å; F212-L216 WeakPolarHBondContact O-CG 3.47Å; F212-L216 PolarHBondContact O-N 3.01Å; F212-L229 HydrophobicContact CD1-CD1 3.86Å; F212-L229 HydrophobicContact CE1-CD1 3.78Å; F212-H232 HydrophobicContact CE2-CB 4.11Å; F212-H232 HydrophobicContact CZ-CB 3.98Å; F212-I237 HydrophobicContact CD1-CG2 4.41Å; F212-I237 HydrophobicContact CE1-CG1 4.18Å; F212-I237 HydrophobicContact CE1-CG2 3.95Å; F212-I237 HydrophobicContact CZ-CB 4.41Å; F212-I237 HydrophobicContact CZ-CG1 4.1Å; F212-I237 HydrophobicContact CZ-CG2 4.24Å; F212-P238 HydrophobicContact CD2-CG 4.05Å; F212-P238 HydrophobicContact CE2-CG 4.36Å; F212-V241 HydrophobicContact CB-CB 4.47Å; F212-V241 HydrophobicContact CB-CG1 4.45Å; F212-V241 HydrophobicContact CB-CG2 3.87Å; F212-V241 HydrophobicContact CD1-CG2 4.13Å; F212-V241 HydrophobicContact CG-CG2 4.02Å; F212-T245 HydrophobicContact CE1-CG2 4.22Å
213	K	92.9	Very high	82.9	Confident	96 Å²	96	83.7 Å²	83.7	42%	0.417	43%	0.433	S	S	.	.	H	α-helix	trans	-58.9	-43	176.6	-70.5	170.6	-169.3	153.5	0	111.9	L209 D210 K211 L216 A217 V241	L209-K213 HydrophobicContact CD1-CG 4.44Å; L209-K213 HydrophobicContact CG-CD 4.48Å; L209-K213 WeakPolarHBondContact O-CG 3.33Å; L209-K213 PolarHBondContact O-N 3.07Å; D210-K213 PolarHBondContact O-N 3.42Å; D210-K213 IonicContact OD1-NZ 3.56Å; D210-K213 PolarHBondContact OD1-NZ 2.79Å; K211-K213 PolarHBondContact O-N 2.86Å; K213-L216 PolarHBondContact O-N 2.74Å; K213-A217 WeakPolarHBondContact O-CB 3.27Å; K213-A217 PolarHBondContact O-N 3.43Å; K213-V241 HydrophobicContact CG-CG1 4.45Å
214	Q	90.9	Very high	82.5	Confident	138 Å²	138	80.4 Å²	80.4	65%	0.645	42%	0.419	S	S	*	.	H	α-helix	trans	-60.4	-49.6	176.9	-71.6	168.7	-4.4	0	0	111.6	D210 K211 F212 L216 A217 S218	D210-Q214 WeakPolarHBondContact O-CG 3.38Å; D210-Q214 PolarHBondContact O-N 3.19Å; K211-Q214 PolarHBondContact O-N 2.74Å; F212-Q214 VanDerWaalsContact C-N 3.33Å; F212-Q214 PolarHBondContact O-N 2.94Å; Q214-L216 PolarHBondContact O-N 3.12Å; Q214-A217 PolarHBondContact O-N 3.36Å; Q214-S218 PolarHBondContact O-N 3.17Å; Q214-S218 VanDerWaalsContact O-N 3.12Å
215	L	90.1	Very high	82.1	Confident	38 Å²	38	72 Å²	72	20%	0.199	39%	0.388	C	S	.	.	H	α-helix	trans	-60.1	-44.9	177.3	-69.5	169.4	0	0	0	112.4	K211 F212 A217 S218 E228	K211-L215 WeakPolarHBondContact O-CG 3.35Å; K211-L215 PolarHBondContact O-N 2.68Å; K211-L215 VanDerWaalsContact O-N 3.1Å; F212-L215 PolarHBondContact O-N 3.32Å; L215-A217 VanDerWaalsContact C-N 3.32Å; L215-A217 PolarHBondContact O-N 2.78Å; L215-S218 WeakPolarHBondContact O-CB 3.4Å; L215-S218 PolarHBondContact O-N 3.16Å; L215-E228 HydrophobicContact CD2-CB 4.28Å
216	L	89.6	Confident	82	Confident	16 Å²	16	68.8 Å²	68.8	8%	0.084	38%	0.375	C	S	.	.	H	α-helix	trans	-70	-27.8	-178.7	-69.7	167.8	0	0	0	113.4	F212 K213 Q214 L229 V241 I244 L248 R260	F212-L216 WeakPolarHBondContact O-CB 3.34Å; F212-L216 WeakPolarHBondContact O-CD1 3.45Å; F212-L216 WeakPolarHBondContact O-CG 3.47Å; F212-L216 PolarHBondContact O-N 3.01Å; K213-L216 PolarHBondContact O-N 2.74Å; Q214-L216 PolarHBondContact O-N 3.12Å; L216-L229 HydrophobicContact CD2-CD1 4.34Å; L216-L229 HydrophobicContact CD2-CD2 4.4Å; L216-V241 HydrophobicContact CD1-CB 3.78Å; L216-V241 HydrophobicContact CD1-CG1 3.77Å; L216-I244 HydrophobicContact CD1-CG2 3.73Å; L216-I244 HydrophobicContact CD2-CG1 4.21Å; L216-I244 HydrophobicContact CD2-CG2 4.26Å; L216-L248 HydrophobicContact CD2-CD1 3.45Å; L216-L248 VanDerWaalsContact CD2-CD1 3.45Å; L216-R260 PolarHBondContact O-NH1 2.71Å
217	A	87.3	Confident	81.9	Confident	51 Å²	51	67.1 Å²	67.1	42%	0.421	37%	0.369	S	S	.	.	H	α-helix	trans	-81.9	-24	177.5	0	0	0	0	0	113.8	K213 Q214 L215 K257	K213-A217 WeakPolarHBondContact O-CB 3.27Å; K213-A217 PolarHBondContact O-N 3.43Å; Q214-A217 PolarHBondContact O-N 3.36Å; L215-A217 VanDerWaalsContact C-N 3.32Å; L215-A217 PolarHBondContact O-N 2.78Å; A217-K257 PolarHBondContact O-NZ 2.93Å
218	S	80.4	Confident	81.9	Confident	25 Å²	25	67.6 Å²	67.6	18%	0.175	37%	0.365	C	S	.	.			trans	-57.6	143.8	-174.4	-177	0	0	0	0	114	Q214 L215 N220	Q214-S218 PolarHBondContact O-N 3.17Å; Q214-S218 VanDerWaalsContact O-N 3.12Å; L215-S218 WeakPolarHBondContact O-CB 3.4Å; L215-S218 PolarHBondContact O-N 3.16Å; S218-N220 WeakPolarHBondContact OG-CB 3.16Å; S218-N220 PolarHBondContact OG-N 2.91Å; S218-N220 PolarHBondContact OG-ND2 3.39Å
219	P	71.5	Confident	81.9	Confident	118 Å²	118	64.1 Å²	64.1	77%	0.766	35%	0.352	S	S	*	.			trans	-89.2	1.3	173.9	37.9	-36.5	0	0	0	113.9
220	N	61.3	Low	81.9	Confident	101 Å²	101	66.9 Å²	66.9	54%	0.54	36%	0.361	S	S	.	.			trans	-64.6	165.5	-170.3	-65.9	-4.5	0	0	0	114.4	S218 I225	S218-N220 WeakPolarHBondContact OG-CB 3.16Å; S218-N220 PolarHBondContact OG-N 2.91Å; S218-N220 PolarHBondContact OG-ND2 3.39Å; N220-I225 HydrophobicContact CB-CD1 3.95Å; N220-I225 HydrophobicContact CB-CG1 3.92Å; N220-I225 WeakPolarHBondContact O-CD1 3.26Å
221	T	57.3	Low	81.8	Confident	114 Å²	114	69.7 Å²	69.7	70%	0.699	37%	0.371	S	S	*	.			trans	-57.4	133.3	-172.9	-25.6	0	0	0	0	113.9	L223 A224 I225	T221-L223 VanDerWaalsContact C-N 3.3Å; T221-L223 PolarHBondContact O-N 3.5Å; T221-A224 PolarHBondContact O-N 3.15Å; T221-I225 PolarHBondContact O-N 3.3Å
222	D	65.9	Low	81.9	Confident	57 Å²	57	67.2 Å²	67.2	31%	0.305	36%	0.361	S	S	.	.	H	α-helix	trans	-41.7	-46.2	-169.8	-73.8	17.5	0	0	0	116.1	T226 A255 N256	D222-T226 WeakPolarHBondContact O-CB 3.33Å; D222-T226 PolarHBondContact O-N 2.82Å; D222-T226 PolarHBondContact O-OG1 3.03Å; D222-A255 HydrophobicContact CB-CB 3.77Å; D222-A255 WeakPolarHBondContact O-CB 3.47Å; D222-N256 WeakPolarHBondContact OD1-CA 3.17Å; D222-N256 VanDerWaalsContact OD1-CB 3.29Å; D222-N256 WeakPolarHBondContact OD1-CB 3.33Å; D222-N256 PolarHBondContact OD1-N 2.86Å
223	L	64.9	Low	82	Confident	151 Å²	151	67.2 Å²	67.2	79%	0.791	36%	0.361	S	S	*	.	H	α-helix	trans	-70.1	-41.8	-175.4	-73.9	159.5	0	0	0	112.9	T221 T226 E227	T221-L223 VanDerWaalsContact C-N 3.3Å; T221-L223 PolarHBondContact O-N 3.5Å; L223-T226 PolarHBondContact O-N 3.28Å; L223-E227 PolarHBondContact O-N 2.76Å
224	A	70.9	Confident	82.1	Confident	62 Å²	62	65.5 Å²	65.5	51%	0.512	35%	0.352	S	S	.	.	H	α-helix	trans	-71.5	-41.5	-175.2	0	0	0	0	0	112.1	T221 T226 E227 E228	T221-A224 PolarHBondContact O-N 3.15Å; A224-T226 VanDerWaalsContact C-N 3.3Å; A224-T226 PolarHBondContact O-N 3.36Å; A224-E227 PolarHBondContact O-N 3.28Å; A224-E228 PolarHBondContact O-N 3.12Å
225	I	75.1	Confident	82.2	Confident	10 Å²	10	61.9 Å²	61.9	5%	0.051	34%	0.342	C	S	.	.	H	α-helix	trans	-60.4	-43.8	173.2	-63.1	-174.9	0	0	0	110.2	N220 T221 E227 L229	N220-I225 HydrophobicContact CB-CD1 3.95Å; N220-I225 HydrophobicContact CB-CG1 3.92Å; N220-I225 WeakPolarHBondContact O-CD1 3.26Å; T221-I225 PolarHBondContact O-N 3.3Å; I225-E227 VanDerWaalsContact C-N 3.32Å; I225-E227 PolarHBondContact O-N 2.68Å; I225-L229 WeakPolarHBondContact O-CB 3.37Å; I225-L229 PolarHBondContact O-N 3.23Å
226	T	81	Confident	82.5	Confident	31 Å²	31	60.3 Å²	60.3	19%	0.19	34%	0.335	C	S	.	.	H	α-helix	trans	-63	-38.6	-176.5	-54.2	0	0	0	0	111.8	D222 L223 A224 R230	D222-T226 WeakPolarHBondContact O-CB 3.33Å; D222-T226 PolarHBondContact O-N 2.82Å; D222-T226 PolarHBondContact O-OG1 3.03Å; L223-T226 PolarHBondContact O-N 3.28Å; A224-T226 VanDerWaalsContact C-N 3.3Å; A224-T226 PolarHBondContact O-N 3.36Å; T226-R230 WeakPolarHBondContact O-CG 3.35Å; T226-R230 PolarHBondContact O-N 2.65Å
227	E	86.3	Confident	82.8	Confident	90 Å²	90	59.8 Å²	59.8	42%	0.421	33%	0.333	S	S	.	.	H	α-helix	trans	-76	-43	-177.4	-157.2	57.6	-147	0	0	113.3	L223 A224 I225 L229 R230 K231	L223-E227 PolarHBondContact O-N 2.76Å; A224-E227 PolarHBondContact O-N 3.28Å; I225-E227 VanDerWaalsContact C-N 3.32Å; I225-E227 PolarHBondContact O-N 2.68Å; E227-L229 VanDerWaalsContact C-N 3.27Å; E227-L229 PolarHBondContact O-N 3.18Å; E227-R230 WeakPolarHBondContact O-CB 3.29Å; E227-R230 PolarHBondContact O-N 3.03Å; E227-R230 IonicContact OE2-CZ 3.45Å; E227-R230 IonicContact OE2-NH1 3.35Å; E227-R230 PolarHBondContact OE2-NH1 2.63Å; E227-K231 WeakPolarHBondContact O-CB 3.31Å; E227-K231 PolarHBondContact O-N 3.11Å
228	E	89.4	Confident	83.2	Confident	73 Å²	73	58.3 Å²	58.3	34%	0.341	32%	0.318	S	S	.	.	H	α-helix	trans	-65.2	-33.5	171.8	-74.2	-63.2	137.8	0	0	111.4	L215 A224 K231 H232	L215-E228 HydrophobicContact CD2-CB 4.28Å; A224-E228 PolarHBondContact O-N 3.12Å; E228-K231 PolarHBondContact O-N 2.98Å; E228-K231 IonicContact OE1-NZ 3.5Å; E228-K231 PolarHBondContact OE1-NZ 3.06Å; E228-K231 WeakPolarHBondContact OE2-CD 3.25Å; E228-K231 IonicContact OE2-NZ 2.66Å; E228-K231 PolarHBondContact OE2-NZ 3.03Å; E228-H232 PolarHBondContact O-CD2 2.94Å; E228-H232 VanDerWaalsContact O-CD2 3.28Å; E228-H232 PolarHBondContact O-N 2.91Å; E228-H232 IonicContact OE2-NE2 2.72Å
229	L	91.9	Very high	83.7	Confident	3 Å²	3	61 Å²	61	2%	0.016	33%	0.325	C	S	.	.	H	α-helix	trans	-64.6	-39	172.6	-171.3	65.6	0	0	0	111.8	F212 L216 I225 E227 S233 T245 L248 L249	F212-L229 HydrophobicContact CD1-CD1 3.86Å; F212-L229 HydrophobicContact CE1-CD1 3.78Å; L216-L229 HydrophobicContact CD2-CD1 4.34Å; L216-L229 HydrophobicContact CD2-CD2 4.4Å; I225-L229 WeakPolarHBondContact O-CB 3.37Å; I225-L229 PolarHBondContact O-N 3.23Å; E227-L229 VanDerWaalsContact C-N 3.27Å; E227-L229 PolarHBondContact O-N 3.18Å; L229-S233 WeakPolarHBondContact O-CB 3.44Å; L229-S233 PolarHBondContact O-N 3.22Å; L229-S233 PolarHBondContact O-OG 3.42Å; L229-T245 HydrophobicContact CD1-CG2 3.93Å; L229-T245 HydrophobicContact CD2-CG2 4.16Å; L229-T245 HydrophobicContact CG-CG2 4.04Å; L229-L248 HydrophobicContact CD2-CB 4.02Å; L229-L248 HydrophobicContact CD2-CD1 4.02Å; L229-L249 HydrophobicContact CB-CD2 4.49Å; L229-L249 HydrophobicContact CD2-CD2 4.2Å; L229-L249 HydrophobicContact CD2-CG 4.42Å; L229-L249 HydrophobicContact CG-CD2 4.12Å
230	R	93.4	Very high	84.7	Confident	68 Å²	68	60.4 Å²	60.4	26%	0.257	31%	0.312	S	S	.	.	H	α-helix	trans	-60.7	-55.5	171.2	-76.2	178.7	-178.3	121	6.5	111.3	T226 E227 H232 S233 W234 L249 A458	T226-R230 WeakPolarHBondContact O-CG 3.35Å; T226-R230 PolarHBondContact O-N 2.65Å; E227-R230 WeakPolarHBondContact O-CB 3.29Å; E227-R230 PolarHBondContact O-N 3.03Å; E227-R230 IonicContact OE2-CZ 3.45Å; E227-R230 IonicContact OE2-NH1 3.35Å; E227-R230 PolarHBondContact OE2-NH1 2.63Å; R230-H232 VanDerWaalsContact C-N 3.3Å; R230-H232 PolarHBondContact O-N 3.05Å; R230-S233 CarbonylContact O-C 3.56Å; R230-S233 WeakPolarHBondContact O-CA 3.36Å; R230-S233 PolarHBondContact O-N 3.3Å; R230-W234 PolarHBondContact O-N 3.42Å; R230-L249 HydrophobicContact CG-CD2 3.73Å; R230-A458 HydrophobicContact CB-CB 4.48Å; R230-A458 WeakPolarHBondContact CB-O 3.48Å; R230-A458 WeakPolarHBondContact CD-O 3.37Å; R230-A458 WeakPolarHBondContact CG-O 3.42Å; R230-A458 WeakPolarHBondContact O-CB 3.13Å
231	K	92.9	Very high	86.3	Confident	114 Å²	114	56.1 Å²	56.1	50%	0.496	29%	0.289	S	S	.	.	H	α-helix	trans	-51.9	-45.1	-179.8	179.4	179.5	163.4	-151.2	0	112.4	E227 E228	E227-K231 WeakPolarHBondContact O-CB 3.31Å; E227-K231 PolarHBondContact O-N 3.11Å; E228-K231 PolarHBondContact O-N 2.98Å; E228-K231 IonicContact OE1-NZ 3.5Å; E228-K231 PolarHBondContact OE1-NZ 3.06Å; E228-K231 WeakPolarHBondContact OE2-CD 3.25Å; E228-K231 IonicContact OE2-NZ 2.66Å; E228-K231 PolarHBondContact OE2-NZ 3.03Å
232	H	93	Very high	88.2	Confident	55 Å²	55	52.3 Å²	52.3	26%	0.255	26%	0.262	S	S	.	.	H	α-helix	trans	-73.4	-32.7	174.4	-77.2	-63.2	0	0	0	114	R208 F212 E228 R230	R208-H232 PolarHBondContact NH2-O 2.68Å; F212-H232 HydrophobicContact CE2-CB 4.11Å; F212-H232 HydrophobicContact CZ-CB 3.98Å; E228-H232 PolarHBondContact O-CD2 2.94Å; E228-H232 VanDerWaalsContact O-CD2 3.28Å; E228-H232 PolarHBondContact O-N 2.91Å; E228-H232 IonicContact OE2-NE2 2.72Å; R230-H232 VanDerWaalsContact C-N 3.3Å; R230-H232 PolarHBondContact O-N 3.05Å
233	S	95.9	Very high	89.7	Confident	0 Å²	0	49.7 Å²	49.7	0%	0	25%	0.248	C	C	.	.	H	α-helix	trans	-75.3	-24.6	178.9	-60.9	0	0	0	0	114	L229 R230 S235 G236 I237 T245	L229-S233 WeakPolarHBondContact O-CB 3.44Å; L229-S233 PolarHBondContact O-N 3.22Å; L229-S233 PolarHBondContact O-OG 3.42Å; R230-S233 CarbonylContact O-C 3.56Å; R230-S233 WeakPolarHBondContact O-CA 3.36Å; R230-S233 PolarHBondContact O-N 3.3Å; S233-S235 PolarHBondContact O-N 2.97Å; S233-G236 WeakPolarHBondContact O-CA 3.23Å; S233-G236 PolarHBondContact O-N 3.43Å; S233-I237 WeakPolarHBondContact OG-CG1 3.26Å; S233-T245 WeakPolarHBondContact OG-CG2 3.2Å
234	W	95.6	Very high	91.2	Very high	60 Å²	60	44.4 Å²	44.4	23%	0.227	22%	0.22	C	C	.	.	H	α-helix	trans	-57.4	-36.1	-178	-160.8	98.8	0	0	0	112.6	R230 G236 T455 A458 E459 F466 L512 Y516	R230-W234 PolarHBondContact O-N 3.42Å; W234-G236 VanDerWaalsContact C-N 3.33Å; W234-G236 PolarHBondContact O-N 3.11Å; W234-T455 HydrophobicContact CD2-CG2 3.66Å; W234-T455 VanDerWaalsContact CE2-CG2 3.49Å; W234-T455 HydrophobicContact CE3-CG2 4.34Å; W234-T455 HydrophobicContact CG-CG2 3.79Å; W234-T455 HydrophobicContact CZ2-CG2 4.01Å; W234-T455 WeakPolarHBondContact O-CG2 3.46Å; W234-T455 PolarHBondContact O-OG1 2.87Å; W234-A458 HydrophobicContact CB-CB 4.04Å; W234-E459 PolarHBondContact NE1-OE2 3.27Å; W234-F466 HydrophobicContact CZ2-CE1 4.22Å; W234-F466 AromaticContact CZ2-CZ 3.81Å; W234-F466 HydrophobicContact CZ2-CZ 3.81Å; W234-L512 HydrophobicContact CH2-CB 4.24Å; W234-Y516 HydrophobicContact CH2-CD2 4.29Å; W234-Y516 HydrophobicContact CH2-CG 4.18Å; W234-Y516 AromaticContact CZ2-CD2 3.68Å; W234-Y516 HydrophobicContact CZ2-CD2 3.68Å; W234-Y516 HydrophobicContact CZ2-CG 4.02Å
235	S	93.5	Very high	92.4	Very high	62 Å²	62	41.5 Å²	41.5	43%	0.434	20%	0.196	S	C	.	.	T	Hydrogen-bonded Turn	trans	-88.2	12	175	46.8	0	0	0	0	114.8	R208 S233 R451	R208-S235 PolarHBondContact NH1-OG 3.43Å; R208-S235 PolarHBondContact NH2-O 2.87Å; R208-S235 PolarHBondContact NH2-OG 3.17Å; S233-S235 PolarHBondContact O-N 2.97Å; S235-R451 VanDerWaalsContact C-NH2 3.32Å; S235-R451 PolarHBondContact O-NH2 2.94Å
236	G	95.2	Very high	93.5	Very high	6 Å²	6	41 Å²	41	6%	0.062	19%	0.194	C	C	.	.			trans	106.1	146.9	177.1	0	0	0	0	0	114	R208 S233 W234	R208-G236 VanDerWaalsContact CZ-O 3.31Å; R208-G236 PolarHBondContact NE-O 3Å; R208-G236 VanDerWaalsContact NE-O 3.12Å; R208-G236 PolarHBondContact NH2-O 3.19Å; S233-G236 WeakPolarHBondContact O-CA 3.23Å; S233-G236 PolarHBondContact O-N 3.43Å; W234-G236 VanDerWaalsContact C-N 3.33Å; W234-G236 PolarHBondContact O-N 3.11Å
237	I	96.2	Very high	94.2	Very high	5 Å²	5	39.9 Å²	39.9	3%	0.026	19%	0.186	C	C	.	.			trans	-107.2	133.8	-176.7	-57.6	160.9	0	0	0	109.6	F212 S233 V241 R242 T245 L249 D454	F212-I237 HydrophobicContact CD1-CG2 4.41Å; F212-I237 HydrophobicContact CE1-CG1 4.18Å; F212-I237 HydrophobicContact CE1-CG2 3.95Å; F212-I237 HydrophobicContact CZ-CB 4.41Å; F212-I237 HydrophobicContact CZ-CG1 4.1Å; F212-I237 HydrophobicContact CZ-CG2 4.24Å; S233-I237 WeakPolarHBondContact OG-CG1 3.26Å; I237-V241 HydrophobicContact CG2-CG2 3.91Å; I237-R242 HydrophobicContact CB-CB 4.44Å; I237-R242 HydrophobicContact CB-CG 4.31Å; I237-R242 HydrophobicContact CG2-CB 4.01Å; I237-R242 HydrophobicContact CG2-CG 4.32Å; I237-R242 PolarHBondContact O-NH2 3.26Å; I237-T245 HydrophobicContact CD1-CG2 3.4Å; I237-T245 HydrophobicContact CG1-CG2 4.01Å; I237-T245 HydrophobicContact CG2-CG2 4.2Å; I237-L249 HydrophobicContact CD1-CD1 4.16Å; I237-D454 HydrophobicContact CB-CB 4.44Å; I237-D454 HydrophobicContact CD1-CB 3.86Å; I237-D454 WeakPolarHBondContact CD1-OD1 3.4Å; I237-D454 HydrophobicContact CG1-CB 3.95Å; I237-D454 PolarHBondContact N-OD2 3.36Å
238	P	95.1	Very high	94.6	Very high	19 Å²	19	36.3 Å²	36.3	12%	0.123	17%	0.169	C	C	.	.			trans	-61.6	146.4	174.4	-21.4	32.6	0	0	0	112.8	R208 L209 F212 E240 V241 R242	R208-P238 HydrophobicContact CG-CG 4.17Å; L209-P238 HydrophobicContact CB-CB 4.31Å; L209-P238 HydrophobicContact CB-CG 4.3Å; L209-P238 HydrophobicContact CD1-CB 4.07Å; F212-P238 HydrophobicContact CD2-CG 4.05Å; F212-P238 HydrophobicContact CE2-CG 4.36Å; P238-E240 VanDerWaalsContact C-N 3.25Å; P238-E240 VanDerWaalsContact CB-OE2 3.27Å; P238-E240 WeakPolarHBondContact CB-OE2 3.21Å; P238-E240 PolarHBondContact O-N 3.49Å; P238-V241 HydrophobicContact CB-CG2 3.93Å; P238-V241 HydrophobicContact CG-CG2 4.12Å; P238-V241 WeakPolarHBondContact O-CG2 3.39Å; P238-V241 PolarHBondContact O-N 2.89Å; P238-R242 PolarHBondContact O-N 2.76Å
239	R	91.8	Very high	94.8	Very high	83 Å²	83	33.5 Å²	33.5	31%	0.313	16%	0.157	S	C	.	.	T	Hydrogen-bonded Turn	trans	-55.2	-40.4	-170.2	-175	-168.3	-175.7	-76.5	14.8	112.4	V241 S350 V353 T354	R239-V241 VanDerWaalsContact C-N 3.29Å; R239-V241 PolarHBondContact O-N 3.45Å; R239-S350 PolarHBondContact NH1-O 2.89Å; R239-V353 PolarHBondContact NH1-O 3.13Å; R239-V353 PolarHBondContact NH2-O 3.24Å; R239-T354 PolarHBondContact NH2-O 3.02Å
240	E	91.4	Very high	94.9	Very high	104 Å²	104	34.3 Å²	34.3	49%	0.486	16%	0.162	S	C	.	.	T	Hydrogen-bonded Turn	trans	-67.6	-28.4	-173	-49.5	72.7	-160.2	0	0	112.6	L209 P238	L209-E240 HydrophobicContact CD1-CB 4.03Å; L209-E240 HydrophobicContact CD1-CG 4.4Å; L209-E240 HydrophobicContact CD2-CG 4.17Å; P238-E240 VanDerWaalsContact C-N 3.25Å; P238-E240 VanDerWaalsContact CB-OE2 3.27Å; P238-E240 WeakPolarHBondContact CB-OE2 3.21Å; P238-E240 PolarHBondContact O-N 3.49Å
241	V	95.3	Very high	94.9	Very high	11 Å²	11	33.6 Å²	33.6	7%	0.067	18%	0.177	C	C	.	.	T	Hydrogen-bonded Turn	trans	-112.4	-6.4	-176.2	-69.8	0	0	0	0	112.9	L209 F212 K213 L216 I237 P238 R239 P243 I244 T245	L209-V241 HydrophobicContact CD1-CG1 3.8Å; L209-V241 HydrophobicContact CD1-CG2 4.06Å; F212-V241 HydrophobicContact CB-CB 4.47Å; F212-V241 HydrophobicContact CB-CG1 4.45Å; F212-V241 HydrophobicContact CB-CG2 3.87Å; F212-V241 HydrophobicContact CD1-CG2 4.13Å; F212-V241 HydrophobicContact CG-CG2 4.02Å; K213-V241 HydrophobicContact CG-CG1 4.45Å; L216-V241 HydrophobicContact CD1-CB 3.78Å; L216-V241 HydrophobicContact CD1-CG1 3.77Å; I237-V241 HydrophobicContact CG2-CG2 3.91Å; P238-V241 HydrophobicContact CB-CG2 3.93Å; P238-V241 HydrophobicContact CG-CG2 4.12Å; P238-V241 WeakPolarHBondContact O-CG2 3.39Å; P238-V241 PolarHBondContact O-N 2.89Å; R239-V241 VanDerWaalsContact C-N 3.29Å; R239-V241 PolarHBondContact O-N 3.45Å; V241-P243 VanDerWaalsContact C-CD 3.48Å; V241-I244 HydrophobicContact CB-CG2 4.48Å; V241-I244 VanDerWaalsContact O-CG2 3.27Å; V241-I244 WeakPolarHBondContact O-CG2 3.36Å; V241-T245 WeakPolarHBondContact O-CB 3.46Å; V241-T245 PolarHBondContact O-N 3.35Å; V241-T245 PolarHBondContact O-OG1 2.86Å
242	R	97.2	Very high	95	Very high	34 Å²	34	28.9 Å²	28.9	13%	0.128	16%	0.156	C	C	.	.	H	α-helix	trans	-55.9	-43.3	177.7	-164.3	180	-66.2	116.6	-0.6	113.7	I237 P238 T245 W246 V347 I450 D454	I237-R242 HydrophobicContact CB-CB 4.44Å; I237-R242 HydrophobicContact CB-CG 4.31Å; I237-R242 HydrophobicContact CG2-CB 4.01Å; I237-R242 HydrophobicContact CG2-CG 4.32Å; I237-R242 PolarHBondContact O-NH2 3.26Å; P238-R242 PolarHBondContact O-N 2.76Å; R242-T245 PolarHBondContact O-N 3.39Å; R242-W246 VanDerWaalsContact CG-CD1 3.46Å; R242-W246 HydrophobicContact CG-CD2 4.2Å; R242-W246 HydrophobicContact CG-CG 4.07Å; R242-W246 HydrophobicContact CG-CZ2 4.49Å; R242-W246 WeakPolarHBondContact O-CB 3.14Å; R242-W246 PolarHBondContact O-N 3.26Å; R242-V347 HydrophobicContact CB-CG1 4.36Å; R242-V347 HydrophobicContact CG-CG1 3.98Å; R242-V347 HydrophobicContact CG-CG2 4.43Å; R242-I450 VanDerWaalsContact CD-CG2 3.45Å; R242-D454 WeakPolarHBondContact CD-OD1 3.27Å; R242-D454 WeakPolarHBondContact CG-OD1 3.33Å; R242-D454 IonicContact CZ-OD2 2.78Å; R242-D454 IonicContact NE-OD1 2.72Å; R242-D454 PolarHBondContact NE-OD1 2.71Å; R242-D454 IonicContact NE-OD2 3.32Å; R242-D454 PolarHBondContact NE-OD2 3.15Å; R242-D454 IonicContact NH2-OD2 3.83Å
243	P	97.3	Very high	95	Very high	2 Å²	2	26.7 Å²	26.7	1%	0.013	15%	0.146	C	C	.	.	H	α-helix	trans	-57.3	-53.7	179.6	-25.8	35.5	0	0	0	113	V241 R247 V347 F348 E351	V241-P243 VanDerWaalsContact C-CD 3.48Å; P243-R247 WeakPolarHBondContact O-CG 3.42Å; P243-R247 PolarHBondContact O-N 3.47Å; P243-V347 HydrophobicContact CB-CG1 4.43Å; P243-V347 HydrophobicContact CG-CG1 4.2Å; P243-F348 HydrophobicContact CB-CD1 4.16Å; P243-E351 HydrophobicContact CB-CB 4.01Å; P243-E351 HydrophobicContact CB-CG 4.05Å; P243-E351 HydrophobicContact CG-CB 3.77Å; P243-E351 HydrophobicContact CG-CG 4.1Å
244	I	96.1	Very high	94.8	Very high	41 Å²	41	27.9 Å²	27.9	21%	0.21	15%	0.154	C	C	.	.	H	α-helix	trans	-67.3	-38.3	179.3	-177.4	60	0	0	0	112.3	L216 V241 R247 L248 L253	L216-I244 HydrophobicContact CD1-CG2 3.73Å; L216-I244 HydrophobicContact CD2-CG1 4.21Å; L216-I244 HydrophobicContact CD2-CG2 4.26Å; V241-I244 HydrophobicContact CB-CG2 4.48Å; V241-I244 VanDerWaalsContact O-CG2 3.27Å; V241-I244 WeakPolarHBondContact O-CG2 3.36Å; I244-R247 PolarHBondContact O-N 3.12Å; I244-L248 HydrophobicContact CD1-CD1 4.39Å; I244-L248 HydrophobicContact CG1-CD1 4.15Å; I244-L248 WeakPolarHBondContact O-CG 3.27Å; I244-L248 PolarHBondContact O-N 3.27Å; I244-L248 VanDerWaalsContact O-N 3.12Å; I244-L253 HydrophobicContact CD1-CD1 3.62Å
245	T	96.7	Very high	94.3	Very high	0 Å²	0	25.6 Å²	25.6	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-66.1	-42.8	178.1	-61	0	0	0	0	112.1	F212 L229 S233 I237 V241 R242 R247 L248 L249	F212-T245 HydrophobicContact CE1-CG2 4.22Å; L229-T245 HydrophobicContact CD1-CG2 3.93Å; L229-T245 HydrophobicContact CD2-CG2 4.16Å; L229-T245 HydrophobicContact CG-CG2 4.04Å; S233-T245 WeakPolarHBondContact OG-CG2 3.2Å; I237-T245 HydrophobicContact CD1-CG2 3.4Å; I237-T245 HydrophobicContact CG1-CG2 4.01Å; I237-T245 HydrophobicContact CG2-CG2 4.2Å; V241-T245 WeakPolarHBondContact O-CB 3.46Å; V241-T245 PolarHBondContact O-N 3.35Å; V241-T245 PolarHBondContact O-OG1 2.86Å; R242-T245 PolarHBondContact O-N 3.39Å; T245-R247 PolarHBondContact O-N 3.09Å; T245-L248 PolarHBondContact O-N 3.23Å; T245-L248 VanDerWaalsContact O-N 3.16Å; T245-L249 HydrophobicContact CG2-CD1 3.69Å; T245-L249 HydrophobicContact CG2-CG 3.99Å; T245-L249 WeakPolarHBondContact O-CG 3.28Å; T245-L249 PolarHBondContact O-N 3.1Å
246	W	97.6	Very high	94	Very high	0 Å²	0	24.8 Å²	24.8	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-61.5	-43.2	175.5	-80.8	26	0	0	0	111.8	R242 L248 S250 P343 F344 V347 F348 I450 W453 D454 Q457	R242-W246 VanDerWaalsContact CG-CD1 3.46Å; R242-W246 HydrophobicContact CG-CD2 4.2Å; R242-W246 HydrophobicContact CG-CG 4.07Å; R242-W246 HydrophobicContact CG-CZ2 4.49Å; R242-W246 WeakPolarHBondContact O-CB 3.14Å; R242-W246 PolarHBondContact O-N 3.26Å; W246-L248 VanDerWaalsContact C-N 3.25Å; W246-L248 PolarHBondContact O-N 3.2Å; W246-S250 VanDerWaalsContact O-CB 3.29Å; W246-S250 WeakPolarHBondContact O-CB 3.16Å; W246-S250 PolarHBondContact O-N 3.1Å; W246-S250 PolarHBondContact O-OG 3.22Å; W246-P343 HydrophobicContact CH2-CB 3.96Å; W246-P343 HydrophobicContact CZ3-CB 4.11Å; W246-F344 AromaticContact CE3-CD1 3.57Å; W246-F344 HydrophobicContact CE3-CD1 3.57Å; W246-F344 AromaticContact CE3-CE1 3.78Å; W246-F344 HydrophobicContact CE3-CE1 3.78Å; W246-F344 AromaticContact CZ3-CD1 3.69Å; W246-F344 HydrophobicContact CZ3-CD1 3.69Å; W246-F344 AromaticContact CZ3-CE1 3.92Å; W246-F344 HydrophobicContact CZ3-CE1 3.92Å; W246-F344 HydrophobicContact CZ3-CG 4.36Å; W246-V347 HydrophobicContact CD2-CB 4.48Å; W246-V347 HydrophobicContact CD2-CG1 4.04Å; W246-V347 HydrophobicContact CD2-CG2 4.32Å; W246-V347 HydrophobicContact CE3-CB 3.98Å; W246-V347 HydrophobicContact CE3-CG1 3.94Å; W246-V347 HydrophobicContact CE3-CG2 3.98Å; W246-V347 HydrophobicContact CG-CG1 4.4Å; W246-V347 HydrophobicContact CH2-CG2 3.78Å; W246-V347 HydrophobicContact CZ2-CG2 4.08Å; W246-V347 HydrophobicContact CZ3-CB 4.06Å; W246-V347 HydrophobicContact CZ3-CG1 4.5Å; W246-V347 HydrophobicContact CZ3-CG2 3.71Å; W246-F348 HydrophobicContact CB-CE1 4.37Å; W246-I450 HydrophobicContact CH2-CB 4.45Å; W246-I450 HydrophobicContact CH2-CG1 4.25Å; W246-I450 HydrophobicContact CH2-CG2 4.22Å; W246-I450 HydrophobicContact CZ2-CB 4.47Å; W246-I450 HydrophobicContact CZ2-CG2 3.92Å; W246-W453 HydrophobicContact CH2-CB 3.89Å; W246-W453 HydrophobicContact CH2-CE3 4.2Å; W246-W453 HydrophobicContact CZ2-CB 3.82Å; W246-W453 HydrophobicContact CZ3-CE3 4.42Å; W246-D454 PolarHBondContact NE1-OD1 2.81Å; W246-Q457 PolarHBondContact O-OE1 3.16Å
247	R	96.8	Very high	93.6	Very high	8 Å²	8	29.7 Å²	29.7	3%	0.03	16%	0.158	C	C	.	.	H	α-helix	trans	-59.8	-34.3	174.5	-66.5	178.4	-174.8	109.4	-2.4	112.8	P243 I244 T245 S250 Y252 L253 F348 E351 D376	P243-R247 WeakPolarHBondContact O-CG 3.42Å; P243-R247 PolarHBondContact O-N 3.47Å; I244-R247 PolarHBondContact O-N 3.12Å; T245-R247 PolarHBondContact O-N 3.09Å; R247-S250 PolarHBondContact O-OG 2.61Å; R247-Y252 HydrophobicContact CB-CD1 4.08Å; R247-Y252 HydrophobicContact CG-CD1 3.95Å; R247-Y252 HydrophobicContact CG-CE1 4.4Å; R247-Y252 WeakPolarHBondContact O-CB 3.39Å; R247-Y252 PolarHBondContact O-N 3.15Å; R247-Y252 VanDerWaalsContact O-N 3.14Å; R247-L253 HydrophobicContact CB-CB 4.33Å; R247-L253 HydrophobicContact CB-CD1 3.64Å; R247-L253 HydrophobicContact CB-CG 3.89Å; R247-L253 HydrophobicContact CG-CD1 4.37Å; R247-L253 PolarHBondContact O-N 3.3Å; R247-F348 HydrophobicContact CG-CE1 3.71Å; R247-F348 HydrophobicContact CG-CZ 3.98Å; R247-E351 IonicContact CZ-OE1 3.72Å; R247-E351 IonicContact CZ-OE2 2.72Å; R247-E351 VanDerWaalsContact CZ-OE2 3.23Å; R247-E351 VanDerWaalsContact NH1-CD 3.26Å; R247-E351 IonicContact NH1-OE1 2.76Å; R247-E351 PolarHBondContact NH1-OE1 3.1Å; R247-E351 IonicContact NH1-OE2 3.26Å; R247-E351 PolarHBondContact NH1-OE2 3.43Å; R247-E351 IonicContact NH2-OE1 3.64Å; R247-E351 IonicContact NH2-OE2 2.6Å; R247-E351 PolarHBondContact NH2-OE2 2.82Å; R247-D376 IonicContact CZ-OD2 2.77Å; R247-D376 IonicContact NE-OD2 2.7Å; R247-D376 PolarHBondContact NE-OD2 3.39Å; R247-D376 IonicContact NH2-OD2 2.81Å; R247-D376 PolarHBondContact NH2-OD2 3.14Å
248	L	94.4	Very high	93.3	Very high	14 Å²	14	37.6 Å²	37.6	7%	0.073	20%	0.195	C	C	.	.	H	α-helix	trans	-77.3	-51.9	177.7	-71.4	166.7	0	0	0	112.4	L216 L229 I244 T245 W246 S250 G251 L253 P254	L216-L248 HydrophobicContact CD2-CD1 3.45Å; L216-L248 VanDerWaalsContact CD2-CD1 3.45Å; L229-L248 HydrophobicContact CD2-CB 4.02Å; L229-L248 HydrophobicContact CD2-CD1 4.02Å; I244-L248 HydrophobicContact CD1-CD1 4.39Å; I244-L248 HydrophobicContact CG1-CD1 4.15Å; I244-L248 WeakPolarHBondContact O-CG 3.27Å; I244-L248 PolarHBondContact O-N 3.27Å; I244-L248 VanDerWaalsContact O-N 3.12Å; T245-L248 PolarHBondContact O-N 3.23Å; T245-L248 VanDerWaalsContact O-N 3.16Å; W246-L248 VanDerWaalsContact C-N 3.25Å; W246-L248 PolarHBondContact O-N 3.2Å; L248-S250 VanDerWaalsContact C-N 3.34Å; L248-S250 PolarHBondContact O-N 2.95Å; L248-G251 PolarHBondContact O-N 2.9Å; L248-L253 HydrophobicContact CD2-CB 3.9Å; L248-L253 HydrophobicContact CG-CB 4.45Å; L248-P254 VanDerWaalsContact CD2-O 3.29Å; L248-P254 WeakPolarHBondContact CD2-O 3.22Å
249	L	94.5	Very high	93.1	Very high	15 Å²	15	43.4 Å²	43.4	8%	0.079	21%	0.214	C	C	.	.	H	α-helix	trans	-64.9	-35.8	-176.2	-68.7	179.4	0	0	0	113	L229 R230 I237 T245 G251 Q457	L229-L249 HydrophobicContact CB-CD2 4.49Å; L229-L249 HydrophobicContact CD2-CD2 4.2Å; L229-L249 HydrophobicContact CD2-CG 4.42Å; L229-L249 HydrophobicContact CG-CD2 4.12Å; R230-L249 HydrophobicContact CG-CD2 3.73Å; I237-L249 HydrophobicContact CD1-CD1 4.16Å; T245-L249 HydrophobicContact CG2-CD1 3.69Å; T245-L249 HydrophobicContact CG2-CG 3.99Å; T245-L249 WeakPolarHBondContact O-CG 3.28Å; T245-L249 PolarHBondContact O-N 3.1Å; L249-G251 PolarHBondContact O-N 3.01Å; L249-Q457 HydrophobicContact CB-CB 3.83Å; L249-Q457 HydrophobicContact CD1-CB 4.06Å
250	S	94.1	Very high	93.1	Very high	19 Å²	19	40.7 Å²	40.7	13%	0.133	20%	0.204	C	C	.	.	T	Hydrogen-bonded Turn	trans	-69	-5.2	172.5	60.3	0	0	0	0	114.1	W246 R247 L248 Y252 C380 K383	W246-S250 VanDerWaalsContact O-CB 3.29Å; W246-S250 WeakPolarHBondContact O-CB 3.16Å; W246-S250 PolarHBondContact O-N 3.1Å; W246-S250 PolarHBondContact O-OG 3.22Å; R247-S250 PolarHBondContact O-OG 2.61Å; L248-S250 VanDerWaalsContact C-N 3.34Å; L248-S250 PolarHBondContact O-N 2.95Å; S250-Y252 PolarHBondContact O-N 3.19Å; S250-C380 PolarHBondContact OG-SG 2.87Å; S250-K383 WeakPolarHBondContact O-CB 3.42Å; S250-K383 VanDerWaalsContact O-CD 3.31Å; S250-K383 WeakPolarHBondContact O-CD 3.19Å; S250-K383 VanDerWaalsContact O-CG 3.31Å; S250-K383 WeakPolarHBondContact O-CG 3.4Å
251	G	92.6	Very high	93.2	Very high	54 Å²	54	43.4 Å²	43.4	56%	0.557	22%	0.217	S	C	*	.	T	Hydrogen-bonded Turn	trans	67.8	19.8	-175.9	0	0	0	0	0	113.8	L248 L249	L248-G251 PolarHBondContact O-N 2.9Å; L249-G251 PolarHBondContact O-N 3.01Å
252	Y	94.9	Very high	93.2	Very high	14 Å²	14	49.1 Å²	49.1	6%	0.055	25%	0.246	C	C	.	.	S	Bend	trans	-76.1	-44.4	174.6	170.7	-130.2	0	0	0	111.4	R247 S250 L264 K267 D376 W379	R247-Y252 HydrophobicContact CB-CD1 4.08Å; R247-Y252 HydrophobicContact CG-CD1 3.95Å; R247-Y252 HydrophobicContact CG-CE1 4.4Å; R247-Y252 WeakPolarHBondContact O-CB 3.39Å; R247-Y252 PolarHBondContact O-N 3.15Å; R247-Y252 VanDerWaalsContact O-N 3.14Å; S250-Y252 PolarHBondContact O-N 3.19Å; Y252-L264 HydrophobicContact CE1-CD1 3.7Å; Y252-K267 HydrophobicContact CE2-CB 3.68Å; Y252-K267 HydrophobicContact CE2-CD 4.18Å; Y252-K267 HydrophobicContact CE2-CG 3.86Å; Y252-D376 HydrophobicContact CE1-CB 4.25Å; Y252-D376 PolarHBondContact OH-OD1 2.94Å; Y252-W379 HydrophobicContact CD2-CB 3.4Å; Y252-W379 AromaticContact CD2-CG 3.88Å; Y252-W379 HydrophobicContact CD2-CG 3.88Å; Y252-W379 HydrophobicContact CE1-CB 4.49Å; Y252-W379 HydrophobicContact CE2-CB 3.34Å; Y252-W379 AromaticContact CE2-CD1 3.44Å; Y252-W379 VanDerWaalsContact CE2-CD1 3.44Å; Y252-W379 HydrophobicContact CE2-CD2 4.32Å; Y252-W379 AromaticContact CE2-CG 3.4Å; Y252-W379 HydrophobicContact CE2-CG 3.4Å; Y252-W379 VanDerWaalsContact CE2-CG 3.4Å; Y252-W379 HydrophobicContact CG-CB 4.02Å; Y252-W379 AromaticContact CZ-CD1 3.8Å
253	L	92.8	Very high	93.1	Very high	10 Å²	10	48.9 Å²	48.9	5%	0.052	25%	0.249	C	C	.	.	S	Bend	trans	-96.6	145.9	169.9	-77.8	180	0	0	0	111.7	I244 R247 L248 R260 L264	I244-L253 HydrophobicContact CD1-CD1 3.62Å; R247-L253 HydrophobicContact CB-CB 4.33Å; R247-L253 HydrophobicContact CB-CD1 3.64Å; R247-L253 HydrophobicContact CB-CG 3.89Å; R247-L253 HydrophobicContact CG-CD1 4.37Å; R247-L253 PolarHBondContact O-N 3.3Å; L248-L253 HydrophobicContact CD2-CB 3.9Å; L248-L253 HydrophobicContact CG-CB 4.45Å; L253-R260 HydrophobicContact CD2-CB 4.17Å; L253-R260 WeakPolarHBondContact CD2-O 3.45Å; L253-L264 HydrophobicContact CD2-CB 3.95Å; L253-L264 HydrophobicContact CD2-CD1 4.07Å; L253-L264 HydrophobicContact CD2-CG 4.49Å
254	P	91.1	Very high	93.1	Very high	24 Å²	24	50.2 Å²	50.2	16%	0.156	26%	0.255	C	S	.	.			trans	-69.4	148.7	168.9	31.7	-35.2	0	0	0	110.8	L248 N256 R259 R260 V263	L248-P254 VanDerWaalsContact CD2-O 3.29Å; L248-P254 WeakPolarHBondContact CD2-O 3.22Å; P254-N256 VanDerWaalsContact C-N 3.34Å; P254-R259 HydrophobicContact CB-CB 4.49Å; P254-R259 HydrophobicContact CG-CB 3.84Å; P254-R260 HydrophobicContact CG-CG 4.28Å; P254-R260 WeakPolarHBondContact O-CG 3.45Å; P254-R260 PolarHBondContact O-NE 2.93Å; P254-V263 HydrophobicContact CG-CB 4.38Å; P254-V263 HydrophobicContact CG-CG2 4.17Å
255	A	87	Confident	93.1	Very high	12 Å²	12	54.3 Å²	54.3	10%	0.099	27%	0.272	C	S	.	.	S	Bend	trans	-62.7	-41.4	171.9	0	0	0	0	0	111.4	D222 K257 R260	D222-A255 HydrophobicContact CB-CB 3.77Å; D222-A255 WeakPolarHBondContact O-CB 3.47Å; A255-K257 PolarHBondContact O-N 2.93Å; A255-K257 VanDerWaalsContact O-N 3.1Å; A255-R260 PolarHBondContact O-NE 2.64Å; A255-R260 PolarHBondContact O-NH2 3.45Å
256	N	86.9	Confident	93.2	Very high	46 Å²	46	59.8 Å²	59.8	25%	0.246	29%	0.292	C	S	.	.	S	Bend	trans	-52.5	115.6	171.6	-180	-67.8	0	0	0	111.6	D222 P254 E258 R259 R260	D222-N256 WeakPolarHBondContact OD1-CA 3.17Å; D222-N256 VanDerWaalsContact OD1-CB 3.29Å; D222-N256 WeakPolarHBondContact OD1-CB 3.33Å; D222-N256 PolarHBondContact OD1-N 2.86Å; P254-N256 VanDerWaalsContact C-N 3.34Å; N256-E258 WeakPolarHBondContact OD1-CB 3.48Å; N256-E258 PolarHBondContact OD1-N 2.97Å; N256-E258 VanDerWaalsContact OD1-N 3.11Å; N256-R259 HydrophobicContact CB-CB 4.39Å; N256-R259 HydrophobicContact CB-CG 4.41Å; N256-R259 PolarHBondContact O-N 2.95Å; N256-R259 WeakPolarHBondContact OD1-CG 3.3Å; N256-R259 PolarHBondContact OD1-N 2.73Å; N256-R260 WeakPolarHBondContact O-CG 3.35Å
257	K	86.9	Confident	93.3	Very high	109 Å²	109	61.5 Å²	61.5	47%	0.474	30%	0.3	S	S	.	.	H	α-helix	trans	-62.1	-44.1	-173.9	-170.8	179.7	-179.7	-173.2	0	113.7	A217 A255 R259 R260	A217-K257 PolarHBondContact O-NZ 2.93Å; A255-K257 PolarHBondContact O-N 2.93Å; A255-K257 VanDerWaalsContact O-N 3.1Å; K257-R259 PolarHBondContact O-N 2.84Å; K257-R260 WeakPolarHBondContact O-CB 3.32Å; K257-R260 PolarHBondContact O-N 2.81Å; K257-R260 VanDerWaalsContact O-N 3.15Å
258	E	88.9	Confident	93.3	Very high	171 Å²	171	62.8 Å²	62.8	80%	0.799	31%	0.305	S	S	*	.	H	α-helix	trans	-62.3	-32.8	-178.2	-54.8	175.4	158.6	0	0	111.9	N256	N256-E258 WeakPolarHBondContact OD1-CB 3.48Å; N256-E258 PolarHBondContact OD1-N 2.97Å; N256-E258 VanDerWaalsContact OD1-N 3.11Å
259	R	90.3	Very high	93.5	Very high	141 Å²	141	67.2 Å²	67.2	53%	0.532	33%	0.325	S	S	.	.	H	α-helix	trans	-82.8	-12.7	179.9	-64.9	175.2	70.8	-153.6	2.3	113.7	P254 N256 K257 V263	P254-R259 HydrophobicContact CB-CB 4.49Å; P254-R259 HydrophobicContact CG-CB 3.84Å; N256-R259 HydrophobicContact CB-CB 4.39Å; N256-R259 HydrophobicContact CB-CG 4.41Å; N256-R259 PolarHBondContact O-N 2.95Å; N256-R259 WeakPolarHBondContact OD1-CG 3.3Å; N256-R259 PolarHBondContact OD1-N 2.73Å; K257-R259 PolarHBondContact O-N 2.84Å; R259-V263 WeakPolarHBondContact O-CB 3.14Å; R259-V263 VanDerWaalsContact O-CG2 3.28Å; R259-V263 WeakPolarHBondContact O-CG2 3.3Å; R259-V263 PolarHBondContact O-N 2.86Å; R259-V263 VanDerWaalsContact O-N 3.09Å
260	R	91.6	Very high	93.7	Very high	26 Å²	26	69.2 Å²	69.2	10%	0.098	33%	0.334	C	S	.	.	H	α-helix	trans	-60.1	-52.7	-173.8	-67.5	179.2	-165.7	159.1	8.4	111.8	L216 L253 P254 A255 N256 K257 V263 L264	L216-R260 PolarHBondContact O-NH1 2.71Å; L253-R260 HydrophobicContact CD2-CB 4.17Å; L253-R260 WeakPolarHBondContact CD2-O 3.45Å; P254-R260 HydrophobicContact CG-CG 4.28Å; P254-R260 WeakPolarHBondContact O-CG 3.45Å; P254-R260 PolarHBondContact O-NE 2.93Å; A255-R260 PolarHBondContact O-NE 2.64Å; A255-R260 PolarHBondContact O-NH2 3.45Å; N256-R260 WeakPolarHBondContact O-CG 3.35Å; K257-R260 WeakPolarHBondContact O-CB 3.32Å; K257-R260 PolarHBondContact O-N 2.81Å; K257-R260 VanDerWaalsContact O-N 3.15Å; R260-V263 PolarHBondContact O-N 2.97Å; R260-L264 VanDerWaalsContact O-CB 3.24Å; R260-L264 WeakPolarHBondContact O-CB 3.42Å; R260-L264 PolarHBondContact O-N 2.87Å
261	E	93.7	Very high	93.9	Very high	161 Å²	161	68.3 Å²	68.3	75%	0.752	33%	0.328	S	S	*	.	H	α-helix	trans	-62.2	-48.6	-175.6	-172.6	-178.8	168.5	0	0	112.6	V263 L264 K265	E261-V263 VanDerWaalsContact C-N 3.35Å; E261-V263 PolarHBondContact O-N 3.21Å; E261-L264 PolarHBondContact O-N 3.24Å; E261-K265 WeakPolarHBondContact O-CB 3.28Å; E261-K265 PolarHBondContact O-N 3.27Å
262	L	95.8	Very high	94.2	Very high	130 Å²	130	66.8 Å²	66.8	68%	0.681	31%	0.306	S	S	*	.	H	α-helix	trans	-61.2	-41.6	178.4	179.1	62.5	0	0	0	112.1	R266	L262-R266 VanDerWaalsContact O-CB 3.23Å; L262-R266 WeakPolarHBondContact O-CB 3.33Å; L262-R266 PolarHBondContact O-N 3.45Å; L262-R266 VanDerWaalsContact O-N 3.14Å
263	V	96.2	Very high	94.4	Very high	30 Å²	30	67.6 Å²	67.6	18%	0.182	32%	0.318	C	S	.	.	H	α-helix	trans	-68.4	-42.3	176.8	171.9	0	0	0	0	111.1	P254 R259 R260 E261 K267	P254-V263 HydrophobicContact CG-CB 4.38Å; P254-V263 HydrophobicContact CG-CG2 4.17Å; R259-V263 WeakPolarHBondContact O-CB 3.14Å; R259-V263 VanDerWaalsContact O-CG2 3.28Å; R259-V263 WeakPolarHBondContact O-CG2 3.3Å; R259-V263 PolarHBondContact O-N 2.86Å; R259-V263 VanDerWaalsContact O-N 3.09Å; R260-V263 PolarHBondContact O-N 2.97Å; E261-V263 VanDerWaalsContact C-N 3.35Å; E261-V263 PolarHBondContact O-N 3.21Å; V263-K267 HydrophobicContact CG1-CG 4.39Å; V263-K267 VanDerWaalsContact O-CB 3.26Å; V263-K267 WeakPolarHBondContact O-CB 3.42Å; V263-K267 PolarHBondContact O-N 3.26Å
264	L	96.3	Very high	94.6	Very high	30 Å²	30	68 Å²	68	16%	0.157	32%	0.32	C	S	.	.	H	α-helix	trans	-59.9	-53.6	179.1	-169.6	62.8	0	0	0	111.2	Y252 L253 R260 E261 R266 K267 R268	Y252-L264 HydrophobicContact CE1-CD1 3.7Å; L253-L264 HydrophobicContact CD2-CB 3.95Å; L253-L264 HydrophobicContact CD2-CD1 4.07Å; L253-L264 HydrophobicContact CD2-CG 4.49Å; R260-L264 VanDerWaalsContact O-CB 3.24Å; R260-L264 WeakPolarHBondContact O-CB 3.42Å; R260-L264 PolarHBondContact O-N 2.87Å; E261-L264 PolarHBondContact O-N 3.24Å; L264-R266 PolarHBondContact O-N 2.86Å; L264-K267 PolarHBondContact O-N 3.41Å; L264-R268 VanDerWaalsContact O-CG 3.27Å; L264-R268 WeakPolarHBondContact O-CG 3.4Å; L264-R268 PolarHBondContact O-N 2.82Å
265	K	97.4	Very high	94.9	Very high	126 Å²	126	68 Å²	68	55%	0.548	32%	0.318	S	S	.	.	H	α-helix	trans	-55.8	-54.5	177.1	176.3	168.7	178	170.1	0	111.3	E261 K267 R268 E269	E261-K265 WeakPolarHBondContact O-CB 3.28Å; E261-K265 PolarHBondContact O-N 3.27Å; K265-K267 VanDerWaalsContact C-N 3.26Å; K265-K267 PolarHBondContact O-N 3.29Å; K265-R268 PolarHBondContact O-N 3.3Å; K265-R268 VanDerWaalsContact O-N 3.12Å; K265-E269 WeakPolarHBondContact CE-OE1 3.39Å; K265-E269 HydrophobicContact CG-CG 4.49Å; K265-E269 WeakPolarHBondContact CG-OE1 3.4Å; K265-E269 WeakPolarHBondContact O-CG 3.49Å; K265-E269 PolarHBondContact O-N 3.2Å
266	R	98.3	Very high	95.4	Very high	115 Å²	115	73.7 Å²	73.7	43%	0.434	34%	0.343	S	S	.	.	H	α-helix	trans	-58.2	-37.3	179.5	-169.6	-163.9	61.6	67.1	0.4	112.3	L262 L264 E270	L262-R266 VanDerWaalsContact O-CB 3.23Å; L262-R266 WeakPolarHBondContact O-CB 3.33Å; L262-R266 PolarHBondContact O-N 3.45Å; L262-R266 VanDerWaalsContact O-N 3.14Å; L264-R266 PolarHBondContact O-N 2.86Å; R266-E270 IonicContact CZ-OE2 3.69Å; R266-E270 IonicContact NH1-OE2 2.72Å; R266-E270 PolarHBondContact NH1-OE2 3.36Å; R266-E270 IonicContact NH2-OE2 3.83Å; R266-E270 VanDerWaalsContact O-CB 3.24Å; R266-E270 WeakPolarHBondContact O-CB 3.46Å; R266-E270 PolarHBondContact O-N 3.21Å
267	K	98.4	Very high	95.8	Very high	36 Å²	36	77.3 Å²	77.3	16%	0.157	36%	0.358	C	S	.	.	H	α-helix	trans	-73.2	-34.1	178.2	-90	-75.8	173.2	-161.7	0	113.4	Y252 V263 L264 K265 E270 Y271 W379	Y252-K267 HydrophobicContact CE2-CB 3.68Å; Y252-K267 HydrophobicContact CE2-CD 4.18Å; Y252-K267 HydrophobicContact CE2-CG 3.86Å; V263-K267 HydrophobicContact CG1-CG 4.39Å; V263-K267 VanDerWaalsContact O-CB 3.26Å; V263-K267 WeakPolarHBondContact O-CB 3.42Å; V263-K267 PolarHBondContact O-N 3.26Å; L264-K267 PolarHBondContact O-N 3.41Å; K265-K267 VanDerWaalsContact C-N 3.26Å; K265-K267 PolarHBondContact O-N 3.29Å; K267-E270 WeakPolarHBondContact CD-OE2 3.43Å; K267-E270 WeakPolarHBondContact CE-OE2 3.27Å; K267-E270 IonicContact NZ-OE1 2.64Å; K267-E270 PolarHBondContact NZ-OE1 3.22Å; K267-E270 IonicContact NZ-OE2 3.47Å; K267-E270 PolarHBondContact NZ-OE2 2.85Å; K267-E270 PolarHBondContact O-N 3.3Å; K267-Y271 PolarHBondContact O-N 3.11Å; K267-Y271 VanDerWaalsContact O-N 3.1Å; K267-W379 HydrophobicContact CD-CD2 3.74Å; K267-W379 HydrophobicContact CD-CE3 4.18Å; K267-W379 HydrophobicContact CD-CG 4.28Å; K267-W379 HydrophobicContact CD-CH2 4.08Å; K267-W379 HydrophobicContact CD-CZ2 3.58Å; K267-W379 HydrophobicContact CD-CZ3 4.34Å; K267-W379 PolarHBondContact O-NE1 3.01Å
268	R	98.6	Very high	96.1	Very high	36 Å²	36	74.9 Å²	74.9	14%	0.136	35%	0.346	C	S	.	.	H	α-helix	trans	-68.2	-45.9	174	-69.1	165	167	-175.7	3.2	110.3	L264 K265 E270 Y271 F272 N372 A375 D376	L264-R268 VanDerWaalsContact O-CG 3.27Å; L264-R268 WeakPolarHBondContact O-CG 3.4Å; L264-R268 PolarHBondContact O-N 2.82Å; K265-R268 PolarHBondContact O-N 3.3Å; K265-R268 VanDerWaalsContact O-N 3.12Å; R268-E270 VanDerWaalsContact C-N 3.35Å; R268-E270 PolarHBondContact O-N 3.4Å; R268-Y271 PolarHBondContact O-N 2.72Å; R268-F272 WeakPolarHBondContact O-CD2 3.49Å; R268-F272 PolarHBondContact O-N 3.19Å; R268-N372 VanDerWaalsContact CD-OD1 3.29Å; R268-N372 WeakPolarHBondContact CD-OD1 3.47Å; R268-N372 PolarHBondContact NH1-ND2 2.84Å; R268-N372 PolarHBondContact NH1-OD1 3.41Å; R268-N372 VanDerWaalsContact NH1-OD1 3.17Å; R268-A375 HydrophobicContact CB-CB 4.15Å; R268-A375 HydrophobicContact CG-CB 3.83Å; R268-D376 IonicContact CZ-OD1 2.92Å; R268-D376 IonicContact CZ-OD2 2.68Å; R268-D376 IonicContact NE-OD1 2.8Å; R268-D376 PolarHBondContact NE-OD1 3.32Å; R268-D376 IonicContact NE-OD2 2.71Å; R268-D376 VanDerWaalsContact NH2-CG 3.3Å; R268-D376 IonicContact NH2-OD1 3.72Å; R268-D376 PolarHBondContact NH2-OD1 3.33Å; R268-D376 VanDerWaalsContact NH2-OD1 3.13Å; R268-D376 IonicContact NH2-OD2 3.96Å; R268-D376 PolarHBondContact NH2-OD2 2.99Å
269	E	98.3	Very high	96.3	Very high	107 Å²	107	67.7 Å²	67.7	50%	0.5	31%	0.312	S	S	.	.	H	α-helix	trans	-56.2	-45.6	170.8	-68.5	166.1	168.4	0	0	111.9	K265 Y271 F272 G273	K265-E269 WeakPolarHBondContact CE-OE1 3.39Å; K265-E269 HydrophobicContact CG-CG 4.49Å; K265-E269 WeakPolarHBondContact CG-OE1 3.4Å; K265-E269 WeakPolarHBondContact O-CG 3.49Å; K265-E269 PolarHBondContact O-N 3.2Å; E269-Y271 VanDerWaalsContact C-N 3.32Å; E269-Y271 PolarHBondContact O-N 2.94Å; E269-F272 PolarHBondContact O-N 3.31Å; E269-G273 PolarHBondContact O-N 3.26Å
270	E	98.5	Very high	96.4	Very high	57 Å²	57	67.8 Å²	67.8	27%	0.266	32%	0.318	S	S	.	.	H	α-helix	trans	-57.8	-39.5	176.3	-171.3	-173.4	147	0	0	112.6	R266 K267 R268 F274 W379	R266-E270 IonicContact CZ-OE2 3.69Å; R266-E270 IonicContact NH1-OE2 2.72Å; R266-E270 PolarHBondContact NH1-OE2 3.36Å; R266-E270 IonicContact NH2-OE2 3.83Å; R266-E270 VanDerWaalsContact O-CB 3.24Å; R266-E270 WeakPolarHBondContact O-CB 3.46Å; R266-E270 PolarHBondContact O-N 3.21Å; K267-E270 WeakPolarHBondContact CD-OE2 3.43Å; K267-E270 WeakPolarHBondContact CE-OE2 3.27Å; K267-E270 IonicContact NZ-OE1 2.64Å; K267-E270 PolarHBondContact NZ-OE1 3.22Å; K267-E270 IonicContact NZ-OE2 3.47Å; K267-E270 PolarHBondContact NZ-OE2 2.85Å; K267-E270 PolarHBondContact O-N 3.3Å; R268-E270 VanDerWaalsContact C-N 3.35Å; R268-E270 PolarHBondContact O-N 3.4Å; E270-F274 HydrophobicContact CG-CE1 4.29Å; E270-F274 HydrophobicContact CG-CE2 4.49Å; E270-F274 HydrophobicContact CG-CZ 3.81Å; E270-F274 WeakPolarHBondContact O-CD1 3.34Å; E270-F274 WeakPolarHBondContact O-CE1 3.38Å; E270-F274 WeakPolarHBondContact O-CG 3.45Å; E270-F274 PolarHBondContact O-N 2.96Å; E270-W379 HydrophobicContact CB-CZ2 4.27Å; E270-W379 HydrophobicContact CG-CH2 4.41Å; E270-W379 HydrophobicContact CG-CZ2 3.99Å; E270-W379 WeakPolarHBondContact OE1-CH2 3.27Å; E270-W379 WeakPolarHBondContact OE1-CZ2 3.48Å
271	Y	98.6	Very high	96.3	Very high	0 Å²	0	67.7 Å²	67.7	0%	0	32%	0.321	C	S	.	.	H	α-helix	trans	-69.8	-42.3	175.3	172.1	-103.1	0	0	0	112.7	K267 R268 E269 G273 F274 I275 I323 E374 A375 F378	K267-Y271 PolarHBondContact O-N 3.11Å; K267-Y271 VanDerWaalsContact O-N 3.1Å; R268-Y271 PolarHBondContact O-N 2.72Å; E269-Y271 VanDerWaalsContact C-N 3.32Å; E269-Y271 PolarHBondContact O-N 2.94Å; Y271-G273 VanDerWaalsContact C-N 3.31Å; Y271-G273 PolarHBondContact O-N 3.48Å; Y271-F274 WeakPolarHBondContact O-CA 3.42Å; Y271-F274 WeakPolarHBondContact O-CB 3.39Å; Y271-F274 PolarHBondContact O-N 2.9Å; Y271-I275 HydrophobicContact CD1-CD1 4.01Å; Y271-I275 HydrophobicContact CE1-CD1 3.28Å; Y271-I275 HydrophobicContact CE1-CG1 4.18Å; Y271-I275 PolarHBondContact O-N 3.06Å; Y271-I323 HydrophobicContact CD2-CG2 4.42Å; Y271-I323 HydrophobicContact CE2-CB 4.35Å; Y271-I323 HydrophobicContact CE2-CG2 4.1Å; Y271-E374 HydrophobicContact CE1-CG 3.67Å; Y271-E374 WeakPolarHBondContact CE1-OE1 3.33Å; Y271-E374 PolarHBondContact OH-OE1 3.16Å; Y271-A375 HydrophobicContact CD1-CB 3.62Å; Y271-A375 HydrophobicContact CE1-CB 4.36Å; Y271-A375 HydrophobicContact CG-CB 4.09Å; Y271-F378 HydrophobicContact CD2-CB 3.82Å; Y271-F378 AromaticContact CD2-CD1 3.34Å; Y271-F378 HydrophobicContact CD2-CD1 3.34Å; Y271-F378 AromaticContact CD2-CD2 3.91Å; Y271-F378 HydrophobicContact CD2-CD2 3.91Å; Y271-F378 AromaticContact CD2-CE1 3.83Å; Y271-F378 HydrophobicContact CD2-CE1 3.83Å; Y271-F378 HydrophobicContact CD2-CE2 4.33Å; Y271-F378 AromaticContact CD2-CG 3.39Å; Y271-F378 HydrophobicContact CD2-CG 3.39Å; Y271-F378 HydrophobicContact CD2-CZ 4.3Å; Y271-F378 HydrophobicContact CE2-CB 3.62Å; Y271-F378 AromaticContact CE2-CD1 3.87Å; Y271-F378 HydrophobicContact CE2-CD1 3.87Å; Y271-F378 AromaticContact CE2-CD2 3.56Å; Y271-F378 HydrophobicContact CE2-CD2 3.56Å; Y271-F378 HydrophobicContact CE2-CE1 4.45Å; Y271-F378 HydrophobicContact CE2-CE2 4.19Å; Y271-F378 AromaticContact CE2-CG 3.38Å; Y271-F378 HydrophobicContact CE2-CG 3.38Å; Y271-F378 HydrophobicContact CG-CD1 4.2Å; Y271-F378 HydrophobicContact CG-CG 4.42Å
272	F	97.9	Very high	96.4	Very high	21 Å²	21	63 Å²	63	9%	0.092	30%	0.297	C	S	.	.	H	α-helix	trans	-66.9	-32.4	177.6	-73.3	-63.7	0	0	0	113.1	R268 E269 F274 I275 E276 R371 A375	R268-F272 WeakPolarHBondContact O-CD2 3.49Å; R268-F272 PolarHBondContact O-N 3.19Å; E269-F272 PolarHBondContact O-N 3.31Å; F272-F274 PolarHBondContact O-N 2.81Å; F272-I275 HydrophobicContact CD1-CD1 3.63Å; F272-I275 HydrophobicContact CE1-CD1 3.65Å; F272-I275 PolarHBondContact O-N 2.85Å; F272-I275 VanDerWaalsContact O-N 3.07Å; F272-E276 WeakPolarHBondContact O-CG 3.33Å; F272-E276 PolarHBondContact O-N 3.37Å; F272-R371 HydrophobicContact CE1-CB 4.16Å; F272-R371 HydrophobicContact CE1-CG 3.85Å; F272-R371 HydrophobicContact CE2-CB 3.74Å; F272-R371 HydrophobicContact CE2-CG 4.26Å; F272-R371 HydrophobicContact CZ-CB 3.34Å; F272-R371 HydrophobicContact CZ-CG 3.55Å; F272-R371 VanDerWaalsContact CZ-O 3.31Å; F272-R371 WeakPolarHBondContact CZ-O 3.16Å; F272-A375 HydrophobicContact CE2-CB 4.09Å; F272-A375 HydrophobicContact CZ-CB 4.4Å
273	G	98.3	Very high	96.1	Very high	31 Å²	31	60.9 Å²	60.9	32%	0.32	29%	0.29	S	S	.	.	H	α-helix	trans	-57.3	-32.5	167.6	0	0	0	0	0	113.2	E269 Y271 Q277	E269-G273 PolarHBondContact O-N 3.26Å; Y271-G273 VanDerWaalsContact C-N 3.31Å; Y271-G273 PolarHBondContact O-N 3.48Å; G273-Q277 WeakPolarHBondContact O-CB 3.09Å; G273-Q277 PolarHBondContact O-N 3.46Å
274	F	98.2	Very high	96	Very high	19 Å²	19	63.5 Å²	63.5	8%	0.083	30%	0.302	C	S	.	.	H	α-helix	trans	-72.9	-37.8	173.2	-52.5	-24.7	0	0	0	112.3	E270 Y271 F272 Q277 Y278 I323 F378 W379	E270-F274 HydrophobicContact CG-CE1 4.29Å; E270-F274 HydrophobicContact CG-CE2 4.49Å; E270-F274 HydrophobicContact CG-CZ 3.81Å; E270-F274 WeakPolarHBondContact O-CD1 3.34Å; E270-F274 WeakPolarHBondContact O-CE1 3.38Å; E270-F274 WeakPolarHBondContact O-CG 3.45Å; E270-F274 PolarHBondContact O-N 2.96Å; Y271-F274 WeakPolarHBondContact O-CA 3.42Å; Y271-F274 WeakPolarHBondContact O-CB 3.39Å; Y271-F274 PolarHBondContact O-N 2.9Å; F272-F274 PolarHBondContact O-N 2.81Å; F274-Q277 PolarHBondContact O-N 3.4Å; F274-Y278 HydrophobicContact CB-CD2 4.07Å; F274-Y278 HydrophobicContact CB-CE2 4.34Å; F274-Y278 HydrophobicContact CD1-CE2 4.42Å; F274-Y278 WeakPolarHBondContact O-CB 3.31Å; F274-Y278 WeakPolarHBondContact O-CD2 3.3Å; F274-Y278 PolarHBondContact O-N 3.06Å; F274-I323 HydrophobicContact CB-CD1 4.33Å; F274-I323 HydrophobicContact CB-CG2 3.66Å; F274-I323 HydrophobicContact CD2-CG2 3.97Å; F274-I323 HydrophobicContact CG-CG2 4.28Å; F274-I323 WeakPolarHBondContact O-CD1 3.15Å; F274-F378 HydrophobicContact CD2-CE1 4.41Å; F274-F378 HydrophobicContact CD2-CZ 4.36Å; F274-F378 HydrophobicContact CE2-CE1 4.29Å; F274-F378 HydrophobicContact CE2-CZ 4.45Å; F274-W379 AromaticContact CE2-CH2 3.81Å; F274-W379 HydrophobicContact CE2-CH2 3.81Å; F274-W379 AromaticContact CE2-CZ2 3.91Å; F274-W379 HydrophobicContact CE2-CZ2 3.91Å; F274-W379 HydrophobicContact CZ-CH2 4.21Å; F274-W379 HydrophobicContact CZ-CZ2 4.42Å
275	I	97.5	Very high	95.7	Very high	23 Å²	23	69 Å²	69	12%	0.118	33%	0.327	C	S	.	.	H	α-helix	trans	-61.5	-48.5	174.4	-71.9	166.9	0	0	0	110.4	Y271 F272 Q277 Y278 Y279 I323 E374	Y271-I275 HydrophobicContact CD1-CD1 4.01Å; Y271-I275 HydrophobicContact CE1-CD1 3.28Å; Y271-I275 HydrophobicContact CE1-CG1 4.18Å; Y271-I275 PolarHBondContact O-N 3.06Å; F272-I275 HydrophobicContact CD1-CD1 3.63Å; F272-I275 HydrophobicContact CE1-CD1 3.65Å; F272-I275 PolarHBondContact O-N 2.85Å; F272-I275 VanDerWaalsContact O-N 3.07Å; I275-Q277 VanDerWaalsContact C-N 3.33Å; I275-Q277 PolarHBondContact O-N 2.85Å; I275-Y278 PolarHBondContact O-N 3.2Å; I275-Y279 VanDerWaalsContact O-CB 3.27Å; I275-Y279 WeakPolarHBondContact O-CB 3.36Å; I275-Y279 PolarHBondContact O-N 2.95Å; I275-I323 HydrophobicContact CG1-CG1 4.19Å; I275-E374 WeakPolarHBondContact CD1-OE1 3.35Å
276	E	96.4	Very high	95.4	Very high	133 Å²	133	70.2 Å²	70.2	62%	0.621	33%	0.334	S	S	*	.	H	α-helix	trans	-62.4	-38.8	177.7	-69.5	171.7	-163.2	0	0	111.9	F272	F272-E276 WeakPolarHBondContact O-CG 3.33Å; F272-E276 PolarHBondContact O-N 3.37Å
277	Q	95.4	Very high	95.1	Very high	121 Å²	121	67.5 Å²	67.5	57%	0.565	33%	0.325	S	S	*	.	H	α-helix	trans	-74.2	-33.8	179.8	-173.5	174.8	15.4	0	0	114	G273 F274 I275	G273-Q277 WeakPolarHBondContact O-CB 3.09Å; G273-Q277 PolarHBondContact O-N 3.46Å; F274-Q277 PolarHBondContact O-N 3.4Å; I275-Q277 VanDerWaalsContact C-N 3.33Å; I275-Q277 PolarHBondContact O-N 2.85Å
278	Y	94.4	Very high	94.8	Very high	58 Å²	58	69.9 Å²	69.9	23%	0.227	34%	0.335	C	S	.	.	H	α-helix	trans	-129.3	-25.9	-166.2	-54	-71.9	0	0	0	116.4	F274 I275 H280 S281 F322 I323 I326	F274-Y278 HydrophobicContact CB-CD2 4.07Å; F274-Y278 HydrophobicContact CB-CE2 4.34Å; F274-Y278 HydrophobicContact CD1-CE2 4.42Å; F274-Y278 WeakPolarHBondContact O-CB 3.31Å; F274-Y278 WeakPolarHBondContact O-CD2 3.3Å; F274-Y278 PolarHBondContact O-N 3.06Å; I275-Y278 PolarHBondContact O-N 3.2Å; Y278-H280 PolarHBondContact O-N 2.88Å; Y278-S281 PolarHBondContact O-N 3.39Å; Y278-S281 PolarHBondContact O-OG 3.44Å; Y278-F322 WeakPolarHBondContact O-CE1 3.13Å; Y278-I323 HydrophobicContact CD2-CD1 4.42Å; Y278-I326 HydrophobicContact CD1-CD1 3.96Å; Y278-I326 HydrophobicContact CD2-CD1 3.88Å; Y278-I326 HydrophobicContact CG-CD1 3.46Å; Y278-I326 VanDerWaalsContact CG-CD1 3.46Å
279	Y	92.9	Very high	94.7	Very high	21 Å²	21	73 Å²	73	8%	0.082	36%	0.355	C	S	.	.	G	3₁₀ helix	trans	-72.8	-19.1	-172.5	-162.3	-113.2	0	0	0	113.2	I275 R282 Y291 E318 R319 F322	I275-Y279 VanDerWaalsContact O-CB 3.27Å; I275-Y279 WeakPolarHBondContact O-CB 3.36Å; I275-Y279 PolarHBondContact O-N 2.95Å; Y279-R282 VanDerWaalsContact O-CD 3.3Å; Y279-R282 WeakPolarHBondContact O-CD 3.46Å; Y279-R282 WeakPolarHBondContact O-CG 3.41Å; Y279-R282 PolarHBondContact O-NH1 3.35Å; Y279-Y291 HydrophobicContact CE2-CE2 4.48Å; Y279-E318 PolarHBondContact OH-OE2 2.77Å; Y279-R319 HydrophobicContact CD1-CG 3.91Å; Y279-R319 HydrophobicContact CD2-CG 3.89Å; Y279-R319 HydrophobicContact CE1-CG 3.59Å; Y279-R319 HydrophobicContact CE2-CB 4.26Å; Y279-R319 HydrophobicContact CE2-CG 3.58Å; Y279-R319 HydrophobicContact CG-CG 4.06Å; Y279-R319 VanDerWaalsContact CZ-CG 3.42Å; Y279-F322 HydrophobicContact CD2-CB 4.4Å; Y279-F322 AromaticContact CD2-CD1 3.83Å; Y279-F322 HydrophobicContact CD2-CD1 3.83Å; Y279-F322 HydrophobicContact CD2-CG 4.3Å; Y279-F322 HydrophobicContact CE2-CB 4.23Å; Y279-F322 HydrophobicContact CE2-CD1 4.38Å; Y279-F322 HydrophobicContact CE2-CG 4.4Å
280	H	91.1	Very high	94.6	Very high	142 Å²	142	69.6 Å²	69.6	66%	0.657	34%	0.341	S	S	*	.	G	3₁₀ helix	trans	-69.8	-31.9	173.4	-67.7	-70.3	0	0	0	113.1	Y278	Y278-H280 PolarHBondContact O-N 2.88Å
281	S	91.2	Very high	94.5	Very high	24 Å²	24	68.5 Å²	68.5	17%	0.168	34%	0.335	C	S	.	.	G	3₁₀ helix	trans	-90	8.3	-179.6	49.2	0	0	0	0	114.2	Y278 T283 D284	Y278-S281 PolarHBondContact O-N 3.39Å; Y278-S281 PolarHBondContact O-OG 3.44Å; S281-T283 PolarHBondContact O-N 2.6Å; S281-T283 VanDerWaalsContact O-N 3.07Å; S281-D284 WeakPolarHBondContact CB-OD2 3.24Å; S281-D284 VanDerWaalsContact O-CB 3.27Å; S281-D284 WeakPolarHBondContact O-CB 3.2Å; S281-D284 PolarHBondContact O-N 3.43Å
282	R	93.9	Very high	94.4	Very high	63 Å²	63	76 Å²	76	24%	0.238	36%	0.363	C	S	.	.	T	Hydrogen-bonded Turn	trans	-59.4	-21.5	-179.9	75.1	-171.1	-174.2	-76.4	-0.4	114.8	Y279 Y291 F322	Y279-R282 VanDerWaalsContact O-CD 3.3Å; Y279-R282 WeakPolarHBondContact O-CD 3.46Å; Y279-R282 WeakPolarHBondContact O-CG 3.41Å; Y279-R282 PolarHBondContact O-NH1 3.35Å; R282-Y291 HydrophobicContact CB-CD1 4.2Å; R282-Y291 HydrophobicContact CB-CD2 4.22Å; R282-Y291 HydrophobicContact CB-CG 3.96Å; R282-Y291 HydrophobicContact CG-CD1 3.81Å; R282-Y291 HydrophobicContact CG-CD2 4.25Å; R282-Y291 HydrophobicContact CG-CE1 3.86Å; R282-Y291 HydrophobicContact CG-CE2 4.32Å; R282-Y291 HydrophobicContact CG-CG 4.02Å; R282-Y291 PolarHBondContact NE-OH 3.04Å; R282-Y291 VanDerWaalsContact NE-OH 3.15Å; R282-Y291 WeakPolarHBondContact O-CB 3.33Å; R282-F322 VanDerWaalsContact CA-CZ 3.43Å; R282-F322 HydrophobicContact CB-CD1 4.26Å; R282-F322 HydrophobicContact CB-CD2 4.01Å; R282-F322 HydrophobicContact CB-CE1 3.82Å; R282-F322 HydrophobicContact CB-CE2 3.54Å; R282-F322 HydrophobicContact CB-CG 4.35Å; R282-F322 HydrophobicContact CB-CZ 3.46Å; R282-F322 VanDerWaalsContact CB-CZ 3.46Å
283	T	91.4	Very high	94.4	Very high	86 Å²	86	79.6 Å²	79.6	53%	0.528	38%	0.38	S	S	.	.	T	Hydrogen-bonded Turn	trans	-89.6	-11.1	176.3	45.6	0	0	0	0	114.1	S281	S281-T283 PolarHBondContact O-N 2.6Å; S281-T283 VanDerWaalsContact O-N 3.07Å
284	D	92.4	Very high	94.4	Very high	84 Å²	84	78.1 Å²	78.1	45%	0.449	37%	0.365	S	S	.	.	S	Bend	trans	-69.4	145.6	-176.8	-60.5	1	0	0	0	110.2	S281 H286 Y287 K288	S281-D284 WeakPolarHBondContact CB-OD2 3.24Å; S281-D284 VanDerWaalsContact O-CB 3.27Å; S281-D284 WeakPolarHBondContact O-CB 3.2Å; S281-D284 PolarHBondContact O-N 3.43Å; D284-H286 PolarHBondContact O-N 2.85Å; D284-Y287 PolarHBondContact O-N 3.27Å; D284-K288 VanDerWaalsContact O-CB 3.31Å; D284-K288 WeakPolarHBondContact O-CB 3.38Å; D284-K288 PolarHBondContact O-N 3.27Å
285	E	90.5	Very high	94.4	Very high	147 Å²	147	82 Å²	82	69%	0.687	38%	0.383	S	S	*	.	T	Hydrogen-bonded Turn	trans	-54	-21.8	-173	-59.6	-61.2	137.8	0	0	114.6	K288	E285-K288 IonicContact OE1-NZ 3.28Å; E285-K288 PolarHBondContact OE1-NZ 2.76Å; E285-K288 WeakPolarHBondContact OE2-CD 3.43Å; E285-K288 IonicContact OE2-NZ 2.76Å; E285-K288 PolarHBondContact OE2-NZ 2.79Å
286	H	90.6	Very high	94.4	Very high	150 Å²	150	84.9 Å²	84.9	69%	0.694	40%	0.398	S	S	*	.	T	Hydrogen-bonded Turn	trans	-73.5	-32.2	174.8	-173.4	29.2	0	0	0	113.9	D284	D284-H286 PolarHBondContact O-N 2.85Å
287	Y	92.8	Very high	94.4	Very high	59 Å²	59	79.2 Å²	79.2	23%	0.231	37%	0.372	C	S	.	.	T	Hydrogen-bonded Turn	trans	-114.3	-14.3	-174.5	-59	-50.9	0	0	0	114	D284 D289 T290 Y291 F322 I326	D284-Y287 PolarHBondContact O-N 3.27Å; Y287-D289 VanDerWaalsContact C-N 3.33Å; Y287-D289 PolarHBondContact O-N 3.24Å; Y287-T290 WeakPolarHBondContact O-CA 3.43Å; Y287-T290 WeakPolarHBondContact O-CB 3.43Å; Y287-T290 PolarHBondContact O-N 3.34Å; Y287-Y291 PolarHBondContact O-N 3.05Å; Y287-F322 HydrophobicContact CD2-CZ 4.34Å; Y287-F322 HydrophobicContact CG-CZ 4.08Å; Y287-I326 HydrophobicContact CD1-CG2 3.87Å; Y287-I326 HydrophobicContact CE1-CG2 3.99Å; Y287-I326 HydrophobicContact CG-CG2 4.46Å
288	K	92.6	Very high	94.5	Very high	85 Å²	85	73.6 Å²	73.6	37%	0.37	35%	0.346	S	S	.	.	H	α-helix	trans	-46.9	-45.1	-179.5	-179.8	178	175.7	-175.1	0	114.4	D284 E285 R292	D284-K288 VanDerWaalsContact O-CB 3.31Å; D284-K288 WeakPolarHBondContact O-CB 3.38Å; D284-K288 PolarHBondContact O-N 3.27Å; E285-K288 IonicContact OE1-NZ 3.28Å; E285-K288 PolarHBondContact OE1-NZ 2.76Å; E285-K288 WeakPolarHBondContact OE2-CD 3.43Å; E285-K288 IonicContact OE2-NZ 2.76Å; E285-K288 PolarHBondContact OE2-NZ 2.79Å; K288-R292 WeakPolarHBondContact O-CB 3.32Å; K288-R292 PolarHBondContact O-N 2.74Å
289	D	95	Very high	94.6	Very high	103 Å²	103	73.1 Å²	73.1	55%	0.551	35%	0.35	S	S	*	.	H	α-helix	trans	-72.4	-31	178.7	-79.7	-25.1	0	0	0	113.1	Y287 Q293	Y287-D289 VanDerWaalsContact C-N 3.33Å; Y287-D289 PolarHBondContact O-N 3.24Å; D289-Q293 WeakPolarHBondContact O-CG 3.43Å; D289-Q293 PolarHBondContact O-N 2.95Å; D289-Q293 PolarHBondContact O-NE2 2.88Å
290	T	96.2	Very high	94.6	Very high	34 Å²	34	77.7 Å²	77.7	21%	0.209	37%	0.367	C	S	.	.	H	α-helix	trans	-67.5	-51.3	172.5	-55.8	0	0	0	0	110.2	Y287 R292 Q293 I294 A325	Y287-T290 WeakPolarHBondContact O-CA 3.43Å; Y287-T290 WeakPolarHBondContact O-CB 3.43Å; Y287-T290 PolarHBondContact O-N 3.34Å; T290-R292 VanDerWaalsContact C-N 3.35Å; T290-R292 PolarHBondContact O-N 3.46Å; T290-Q293 PolarHBondContact O-N 3.32Å; T290-I294 HydrophobicContact CG2-CD1 4.19Å; T290-I294 WeakPolarHBondContact O-CG1 3.36Å; T290-I294 PolarHBondContact O-N 2.75Å; T290-A325 HydrophobicContact CG2-CB 3.8Å
291	Y	97.4	Very high	94.7	Very high	34 Å²	34	71 Å²	71	13%	0.133	34%	0.336	C	S	.	.	H	α-helix	trans	-63.3	-40.3	179.2	-177.5	-125.3	0	0	0	112	Y279 R282 Y287 Q293 I294 H295 E318 F322	Y279-Y291 HydrophobicContact CE2-CE2 4.48Å; R282-Y291 HydrophobicContact CB-CD1 4.2Å; R282-Y291 HydrophobicContact CB-CD2 4.22Å; R282-Y291 HydrophobicContact CB-CG 3.96Å; R282-Y291 HydrophobicContact CG-CD1 3.81Å; R282-Y291 HydrophobicContact CG-CD2 4.25Å; R282-Y291 HydrophobicContact CG-CE1 3.86Å; R282-Y291 HydrophobicContact CG-CE2 4.32Å; R282-Y291 HydrophobicContact CG-CG 4.02Å; R282-Y291 PolarHBondContact NE-OH 3.04Å; R282-Y291 VanDerWaalsContact NE-OH 3.15Å; R282-Y291 WeakPolarHBondContact O-CB 3.33Å; Y287-Y291 PolarHBondContact O-N 3.05Å; Y291-Q293 VanDerWaalsContact C-N 3.35Å; Y291-Q293 PolarHBondContact O-N 3.04Å; Y291-I294 PolarHBondContact O-N 3.21Å; Y291-H295 WeakPolarHBondContact O-CB 3.39Å; Y291-H295 PolarHBondContact O-N 3.03Å; Y291-E318 HydrophobicContact CE2-CB 4.24Å; Y291-E318 HydrophobicContact CE2-CG 4.28Å; Y291-E318 WeakPolarHBondContact CE2-OE2 3.45Å; Y291-E318 VanDerWaalsContact CZ-OE2 3.25Å; Y291-E318 PolarHBondContact OH-OE2 3.31Å; Y291-F322 HydrophobicContact CD2-CD2 4.14Å; Y291-F322 HydrophobicContact CG-CD2 4.41Å
292	R	97.1	Very high	94.6	Very high	157 Å²	157	70.4 Å²	70.4	59%	0.592	33%	0.331	S	S	*	.	H	α-helix	trans	-60.4	-39.4	176.2	-178.8	-179.4	-179	-163.7	1.2	113.1	K288 T290 I296	K288-R292 WeakPolarHBondContact O-CB 3.32Å; K288-R292 PolarHBondContact O-N 2.74Å; T290-R292 VanDerWaalsContact C-N 3.35Å; T290-R292 PolarHBondContact O-N 3.46Å; R292-I296 HydrophobicContact CG-CD1 3.92Å; R292-I296 WeakPolarHBondContact O-CB 3.31Å; R292-I296 WeakPolarHBondContact O-CD1 3.46Å; R292-I296 WeakPolarHBondContact O-CG1 3.47Å; R292-I296 PolarHBondContact O-N 2.91Å; R292-I296 VanDerWaalsContact O-N 3.12Å
293	Q	97.6	Very high	94.3	Very high	98 Å²	98	69.9 Å²	69.9	46%	0.458	34%	0.336	S	S	.	.	H	α-helix	trans	-66.1	-45.9	176	-75.7	168.7	98.4	0	0	111.1	D289 T290 Y291 H295 I296 D297 Y333	D289-Q293 WeakPolarHBondContact O-CG 3.43Å; D289-Q293 PolarHBondContact O-N 2.95Å; D289-Q293 PolarHBondContact O-NE2 2.88Å; T290-Q293 PolarHBondContact O-N 3.32Å; Y291-Q293 VanDerWaalsContact C-N 3.35Å; Y291-Q293 PolarHBondContact O-N 3.04Å; Q293-H295 PolarHBondContact O-N 2.71Å; Q293-I296 PolarHBondContact O-N 3.1Å; Q293-D297 PolarHBondContact O-N 3.23Å; Q293-Y333 HydrophobicContact CB-CD1 3.79Å; Q293-Y333 HydrophobicContact CB-CE1 4.03Å
294	I	98.2	Very high	94.2	Very high	0 Å²	0	70.4 Å²	70.4	0%	0	34%	0.335	C	S	.	.	H	α-helix	trans	-58.9	-49	176.5	-62.3	164.5	0	0	0	110.6	T290 Y291 I296 D297 I298 E318 L321 F322 Y333	T290-I294 HydrophobicContact CG2-CD1 4.19Å; T290-I294 WeakPolarHBondContact O-CG1 3.36Å; T290-I294 PolarHBondContact O-N 2.75Å; Y291-I294 PolarHBondContact O-N 3.21Å; I294-I296 PolarHBondContact O-N 2.9Å; I294-D297 PolarHBondContact O-N 2.9Å; I294-I298 HydrophobicContact CG2-CG1 3.89Å; I294-I298 WeakPolarHBondContact O-CG1 3.18Å; I294-I298 PolarHBondContact O-N 2.93Å; I294-E318 HydrophobicContact CG2-CB 4.47Å; I294-E318 HydrophobicContact CG2-CG 4.15Å; I294-L321 HydrophobicContact CD1-CB 4.01Å; I294-L321 HydrophobicContact CG1-CB 4.27Å; I294-L321 HydrophobicContact CG2-CB 4.01Å; I294-L321 HydrophobicContact CG2-CD1 4.01Å; I294-F322 HydrophobicContact CD1-CB 4.12Å; I294-F322 HydrophobicContact CD1-CD2 4.48Å; I294-Y333 HydrophobicContact CD1-CD2 4.19Å; I294-Y333 HydrophobicContact CD1-CG 4.11Å; I294-Y333 HydrophobicContact CG1-CD1 3.78Å; I294-Y333 HydrophobicContact CG1-CD2 3.59Å; I294-Y333 HydrophobicContact CG1-CE1 4.13Å; I294-Y333 HydrophobicContact CG1-CE2 3.97Å; I294-Y333 HydrophobicContact CG1-CG 3.49Å; I294-Y333 VanDerWaalsContact CG1-CG 3.49Å
295	H	97.6	Very high	94	Very high	100 Å²	100	66.5 Å²	66.5	46%	0.463	31%	0.314	S	S	.	.	H	α-helix	trans	-62	-25.7	178.9	-173.9	65.7	0	0	0	113.6	Y291 Q293 P299 E318	Y291-H295 WeakPolarHBondContact O-CB 3.39Å; Y291-H295 PolarHBondContact O-N 3.03Å; Q293-H295 PolarHBondContact O-N 2.71Å; H295-P299 WeakPolarHBondContact O-CD 3.2Å; H295-E318 IonicContact CE1-OE1 3.41Å; H295-E318 IonicContact CG-OE1 3.91Å; H295-E318 IonicContact ND1-OE1 3.31Å; H295-E318 PolarHBondContact ND1-OE1 2.96Å
296	I	97.1	Very high	94.1	Very high	84 Å²	84	62.3 Å²	62.3	43%	0.431	30%	0.299	S	S	.	.	H	α-helix	trans	-81.9	-30	173.7	-72.5	167.8	0	0	0	111.9	R292 Q293 I294 R300	R292-I296 HydrophobicContact CG-CD1 3.92Å; R292-I296 WeakPolarHBondContact O-CB 3.31Å; R292-I296 WeakPolarHBondContact O-CD1 3.46Å; R292-I296 WeakPolarHBondContact O-CG1 3.47Å; R292-I296 PolarHBondContact O-N 2.91Å; R292-I296 VanDerWaalsContact O-N 3.12Å; Q293-I296 PolarHBondContact O-N 3.1Å; I294-I296 PolarHBondContact O-N 2.9Å; I296-R300 PolarHBondContact O-NE 3.4Å
297	D	97.6	Very high	94.4	Very high	13 Å²	13	55.2 Å²	55.2	7%	0.07	27%	0.266	C	S	.	.	H	α-helix	trans	-88.2	-33.6	-177.2	-75.7	-9.6	0	0	0	113.7	Q293 I294 R300 T301 Y333 Q335	Q293-D297 PolarHBondContact O-N 3.23Å; I294-D297 PolarHBondContact O-N 2.9Å; D297-R300 CarbonylContact O-C 3.54Å; D297-R300 WeakPolarHBondContact O-CA 3.42Å; D297-R300 PolarHBondContact O-N 3.44Å; D297-R300 IonicContact OD1-CZ 2.74Å; D297-R300 IonicContact OD1-NH2 2.68Å; D297-R300 PolarHBondContact OD1-NH2 3.32Å; D297-T301 PolarHBondContact O-N 3.4Å; D297-T301 VanDerWaalsContact O-N 3.11Å; D297-T301 PolarHBondContact O-OG1 2.99Å; D297-Y333 WeakPolarHBondContact CB-OH 3.17Å; D297-Y333 VanDerWaalsContact OD2-CE1 3.3Å; D297-Y333 WeakPolarHBondContact OD2-CE1 3.32Å; D297-Y333 PolarHBondContact OD2-OH 3.37Å; D297-Q335 WeakPolarHBondContact OD2-CG 3.32Å
298	I	97.6	Very high	94.5	Very high	4 Å²	4	52.6 Å²	52.6	2%	0.021	26%	0.256	C	S	.	.	G	3₁₀ helix	trans	-61.7	-49.5	-175.3	-75.4	-49.7	0	0	0	113.7	I294 R300 T301 Q314 F317 E318 L321 N338	I294-I298 HydrophobicContact CG2-CG1 3.89Å; I294-I298 WeakPolarHBondContact O-CG1 3.18Å; I294-I298 PolarHBondContact O-N 2.93Å; I298-R300 PolarHBondContact O-N 3.04Å; I298-T301 VanDerWaalsContact O-CB 3.31Å; I298-T301 WeakPolarHBondContact O-CB 3.17Å; I298-T301 PolarHBondContact O-N 2.91Å; I298-T301 PolarHBondContact O-OG1 3.36Å; I298-Q314 HydrophobicContact CG2-CB 3.59Å; I298-Q314 HydrophobicContact CG2-CG 3.7Å; I298-F317 HydrophobicContact CD1-CB 3.64Å; I298-F317 HydrophobicContact CD1-CD2 4Å; I298-F317 HydrophobicContact CD1-CG 4.32Å; I298-F317 HydrophobicContact CG1-CB 4.16Å; I298-F317 HydrophobicContact CG2-CB 4.35Å; I298-E318 HydrophobicContact CG1-CG 4.3Å; I298-L321 HydrophobicContact CD1-CD1 3.57Å; I298-L321 HydrophobicContact CG1-CD1 4.19Å; I298-N338 HydrophobicContact CD1-CB 4.05Å
299	P	95.4	Very high	94.7	Very high	48 Å²	48	52.4 Å²	52.4	31%	0.312	26%	0.257	S	S	.	.	G	3₁₀ helix	trans	-59.9	-20.4	175	-25	35.5	0	0	0	113.9	H295 Q309	H295-P299 WeakPolarHBondContact O-CD 3.2Å; P299-Q309 PolarHBondContact O-NE2 2.86Å
300	R	94	Very high	94.8	Very high	116 Å²	116	48.9 Å²	48.9	44%	0.438	24%	0.237	S	C	.	.	G	3₁₀ helix	trans	-97.4	3.1	179.9	-52.2	-172.2	-63.7	154.3	3.7	113.2	I296 D297 I298	I296-R300 PolarHBondContact O-NE 3.4Å; D297-R300 CarbonylContact O-C 3.54Å; D297-R300 WeakPolarHBondContact O-CA 3.42Å; D297-R300 PolarHBondContact O-N 3.44Å; D297-R300 IonicContact OD1-CZ 2.74Å; D297-R300 IonicContact OD1-NH2 2.68Å; D297-R300 PolarHBondContact OD1-NH2 3.32Å; I298-R300 PolarHBondContact O-N 3.04Å
301	T	92.6	Very high	94.9	Very high	2 Å²	2	51.7 Å²	51.7	1%	0.012	26%	0.256	C	S	.	.	S	Bend	trans	-83.9	124.3	177.7	-59.3	0	0	0	0	109.3	D297 I298 N338 T342	D297-T301 PolarHBondContact O-N 3.4Å; D297-T301 VanDerWaalsContact O-N 3.11Å; D297-T301 PolarHBondContact O-OG1 2.99Å; I298-T301 VanDerWaalsContact O-CB 3.31Å; I298-T301 WeakPolarHBondContact O-CB 3.17Å; I298-T301 PolarHBondContact O-N 2.91Å; I298-T301 PolarHBondContact O-OG1 3.36Å; T301-N338 PolarHBondContact OG1-ND2 2.78Å; T301-T342 HydrophobicContact CG2-CG2 3.92Å
302	N	88.9	Confident	94.8	Very high	12 Å²	12	51.5 Å²	51.5	6%	0.064	26%	0.261	C	S	.	.	S	Bend	trans	41.6	56.4	-178	-70.2	-18.8	0	0	0	114.9	L304 I305 F308	N302-L304 PolarHBondContact O-N 3.23Å; N302-I305 HydrophobicContact CB-CD1 4.37Å; N302-I305 PolarHBondContact O-N 2.94Å; N302-I305 VanDerWaalsContact O-N 3.1Å; N302-F308 HydrophobicContact CB-CD2 3.39Å; N302-F308 HydrophobicContact CB-CE2 3.74Å; N302-F308 HydrophobicContact CB-CG 4.24Å
303	P	88.6	Confident	94.9	Very high	52 Å²	52	44.1 Å²	44.1	34%	0.338	23%	0.233	S	C	.	.	T	Hydrogen-bonded Turn	trans	-69.6	-4.1	-163.6	30.2	-38	0	0	0	115.7
304	L	88	Confident	94.9	Very high	97 Å²	97	41.1 Å²	41.1	51%	0.508	22%	0.219	S	C	.	.	T	Hydrogen-bonded Turn	trans	-97.5	-10.1	177.2	-54.3	-175.6	0	0	0	113.5	I184 P185 A188 N302	I184-L304 HydrophobicContact CG2-CD1 3.98Å; I184-L304 HydrophobicContact CG2-CD2 4.29Å; I184-L304 HydrophobicContact CG2-CG 4.42Å; P185-L304 WeakPolarHBondContact O-CD1 3.15Å; A188-L304 HydrophobicContact CB-CB 4.26Å; N302-L304 PolarHBondContact O-N 3.23Å
305	I	89.1	Confident	94.9	Very high	1 Å²	1	46.1 Å²	46.1	1%	0.005	24%	0.243	C	C	.	.	S	Bend	trans	-99.5	118.7	179.3	-67.6	163.7	0	0	0	108.5	A188 I190 N302 L307 F308 E358	A188-I305 HydrophobicContact CB-CD1 3.79Å; A188-I305 HydrophobicContact CB-CG1 3.98Å; A188-I305 WeakPolarHBondContact O-CG1 3.46Å; I190-I305 HydrophobicContact CD1-CD1 4.23Å; I190-I305 HydrophobicContact CD1-CG2 3.86Å; I190-I305 HydrophobicContact CG1-CD1 3.73Å; I190-I305 HydrophobicContact CG1-CG1 4.44Å; I190-I305 HydrophobicContact CG1-CG2 4.26Å; N302-I305 HydrophobicContact CB-CD1 4.37Å; N302-I305 PolarHBondContact O-N 2.94Å; N302-I305 VanDerWaalsContact O-N 3.1Å; I305-L307 VanDerWaalsContact C-N 3.3Å; I305-L307 HydrophobicContact CG2-CB 3.94Å; I305-L307 PolarHBondContact O-N 3.44Å; I305-F308 HydrophobicContact CB-CD2 3.84Å; I305-F308 HydrophobicContact CB-CE2 4.08Å; I305-F308 HydrophobicContact CD1-CD2 4.43Å; I305-F308 HydrophobicContact CD1-CE2 3.95Å; I305-F308 HydrophobicContact CG2-CD2 3.81Å; I305-F308 HydrophobicContact CG2-CE2 3.83Å; I305-F308 PolarHBondContact O-N 3.42Å; I305-E358 HydrophobicContact CG2-CB 4.31Å; I305-E358 HydrophobicContact CG2-CG 4.4Å
306	P	93.1	Very high	94.9	Very high	60 Å²	60	41.5 Å²	41.5	39%	0.39	22%	0.222	S	C	.	.	G	3₁₀ helix	trans	-58.3	-34.5	-174.3	-30.2	39.7	0	0	0	115	F308 Q309 Q310 N359	P306-F308 VanDerWaalsContact C-N 3.3Å; P306-F308 PolarHBondContact O-N 3.47Å; P306-Q309 WeakPolarHBondContact O-CA 3.13Å; P306-Q309 WeakPolarHBondContact O-CB 3.24Å; P306-Q309 PolarHBondContact O-N 3.05Å; P306-Q310 PolarHBondContact O-N 3.22Å; P306-N359 WeakPolarHBondContact CG-OD1 3.34Å
307	L	95.4	Very high	95	Very high	0 Å²	0	37.7 Å²	37.7	0%	0	20%	0.202	C	C	.	.	G	3₁₀ helix	trans	-45.6	-49.2	174.9	-176.4	67.9	0	0	0	113.3	I190 I305 Q309 Q310 V313 F345 V346 L349 V357 E358 V362	I190-L307 HydrophobicContact CD1-CD2 4.33Å; I305-L307 VanDerWaalsContact C-N 3.3Å; I305-L307 HydrophobicContact CG2-CB 3.94Å; I305-L307 PolarHBondContact O-N 3.44Å; L307-Q309 PolarHBondContact O-N 2.8Å; L307-Q310 WeakPolarHBondContact O-CB 3.44Å; L307-Q310 PolarHBondContact O-N 2.86Å; L307-V313 HydrophobicContact CD1-CG2 4.15Å; L307-V313 HydrophobicContact CG-CG2 4.48Å; L307-V313 WeakPolarHBondContact O-CB 3.48Å; L307-V313 WeakPolarHBondContact O-CG2 3.1Å; L307-F345 HydrophobicContact CD1-CE1 4.4Å; L307-F345 HydrophobicContact CD2-CD1 4.36Å; L307-F345 HydrophobicContact CD2-CE1 4.18Å; L307-F345 HydrophobicContact CG-CE1 4.38Å; L307-V346 HydrophobicContact CD2-CG2 3.88Å; L307-L349 HydrophobicContact CD1-CD2 3.67Å; L307-L349 HydrophobicContact CD2-CD2 3.99Å; L307-L349 HydrophobicContact CG-CD2 4.48Å; L307-V357 HydrophobicContact CD2-CG1 4.48Å; L307-E358 PolarHBondContact N-O 2.85Å; L307-V362 HydrophobicContact CD1-CG2 3.53Å
308	F	96.3	Very high	95.1	Very high	4 Å²	4	37.7 Å²	37.7	2%	0.018	20%	0.202	C	C	.	.	G	3₁₀ helix	trans	-80.1	-3.5	-176.8	-51.4	-64.2	0	0	0	113.5	I190 N302 I305 P306 V313 Q314 F317 T342 F345 V346 L446	I190-F308 HydrophobicContact CD1-CE2 4.27Å; I190-F308 HydrophobicContact CD1-CZ 4.35Å; N302-F308 HydrophobicContact CB-CD2 3.39Å; N302-F308 HydrophobicContact CB-CE2 3.74Å; N302-F308 HydrophobicContact CB-CG 4.24Å; I305-F308 HydrophobicContact CB-CD2 3.84Å; I305-F308 HydrophobicContact CB-CE2 4.08Å; I305-F308 HydrophobicContact CD1-CD2 4.43Å; I305-F308 HydrophobicContact CD1-CE2 3.95Å; I305-F308 HydrophobicContact CG2-CD2 3.81Å; I305-F308 HydrophobicContact CG2-CE2 3.83Å; I305-F308 PolarHBondContact O-N 3.42Å; P306-F308 VanDerWaalsContact C-N 3.3Å; P306-F308 PolarHBondContact O-N 3.47Å; F308-V313 HydrophobicContact CD1-CG1 4.02Å; F308-Q314 WeakPolarHBondContact O-CG 3.44Å; F308-Q314 PolarHBondContact O-NE2 2.9Å; F308-F317 HydrophobicContact CD1-CE1 4.44Å; F308-F317 HydrophobicContact CD1-CE2 4.35Å; F308-F317 AromaticContact CD1-CZ 3.92Å; F308-F317 HydrophobicContact CD1-CZ 3.92Å; F308-F317 HydrophobicContact CE1-CE1 4.47Å; F308-F317 HydrophobicContact CE1-CE2 4.38Å; F308-F317 AromaticContact CE1-CZ 3.75Å; F308-F317 HydrophobicContact CE1-CZ 3.75Å; F308-T342 HydrophobicContact CD1-CG2 4.42Å; F308-T342 HydrophobicContact CE1-CG2 3.91Å; F308-T342 HydrophobicContact CZ-CG2 3.98Å; F308-F345 HydrophobicContact CE1-CD1 4.48Å; F308-V346 HydrophobicContact CE1-CG2 4.25Å; F308-V346 HydrophobicContact CZ-CG2 3.76Å; F308-L446 HydrophobicContact CE2-CD2 4.43Å; F308-L446 HydrophobicContact CZ-CD2 4.17Å
309	Q	96.1	Very high	95.1	Very high	81 Å²	81	39.5 Å²	39.5	38%	0.379	21%	0.208	S	C	.	.	G	3₁₀ helix	trans	-95	-4.7	173.2	-57.8	-58.2	-62.9	0	0	112.4	P299 P306 L307	P299-Q309 PolarHBondContact O-NE2 2.86Å; P306-Q309 WeakPolarHBondContact O-CA 3.13Å; P306-Q309 WeakPolarHBondContact O-CB 3.24Å; P306-Q309 PolarHBondContact O-N 3.05Å; L307-Q309 PolarHBondContact O-N 2.8Å
310	Q	97	Very high	95.3	Very high	29 Å²	29	37.2 Å²	37.2	14%	0.136	19%	0.193	C	C	.	.	S	Bend	trans	-73.6	129	173.1	-62.8	173.5	17.1	0	0	110.6	P306 L307 A312 V313 Q314 F360	P306-Q310 PolarHBondContact O-N 3.22Å; L307-Q310 WeakPolarHBondContact O-CB 3.44Å; L307-Q310 PolarHBondContact O-N 2.86Å; Q310-A312 VanDerWaalsContact C-N 3.27Å; Q310-A312 PolarHBondContact O-N 3.34Å; Q310-V313 HydrophobicContact CB-CB 4.32Å; Q310-V313 HydrophobicContact CB-CG2 4.02Å; Q310-V313 PolarHBondContact O-N 2.88Å; Q310-Q314 PolarHBondContact O-N 3.44Å; Q310-F360 PolarHBondContact NE2-O 3.27Å
311	P	97.4	Very high	95.5	Very high	93 Å²	93	31.7 Å²	31.7	60%	0.604	17%	0.173	S	C	*	.	H	α-helix	trans	-55.8	-37.8	179	-28.6	36	0	0	0	113.9	V313 Q314 E315	P311-V313 VanDerWaalsContact C-N 3.33Å; P311-V313 PolarHBondContact O-N 3.25Å; P311-Q314 PolarHBondContact O-N 3.42Å; P311-E315 PolarHBondContact O-N 2.87Å
312	A	97.1	Very high	95.8	Very high	30 Å²	30	31.6 Å²	31.6	25%	0.248	17%	0.172	C	C	.	.	H	α-helix	trans	-59.8	-41.2	176.8	0	0	0	0	0	112.5	Q310 V316	Q310-A312 VanDerWaalsContact C-N 3.27Å; Q310-A312 PolarHBondContact O-N 3.34Å; A312-V316 VanDerWaalsContact O-CG2 3.26Å; A312-V316 WeakPolarHBondContact O-CG2 3.37Å; A312-V316 PolarHBondContact O-N 2.72Å; A312-V316 VanDerWaalsContact O-N 3.1Å
313	V	98.1	Very high	96.2	Very high	2 Å²	2	31 Å²	31	1%	0.012	17%	0.169	C	C	.	.	H	α-helix	trans	-71.5	-39.2	176.9	-179.1	0	0	0	0	110.7	L307 F308 Q310 P311 V316 F317 F345 V362	L307-V313 HydrophobicContact CD1-CG2 4.15Å; L307-V313 HydrophobicContact CG-CG2 4.48Å; L307-V313 WeakPolarHBondContact O-CB 3.48Å; L307-V313 WeakPolarHBondContact O-CG2 3.1Å; F308-V313 HydrophobicContact CD1-CG1 4.02Å; Q310-V313 HydrophobicContact CB-CB 4.32Å; Q310-V313 HydrophobicContact CB-CG2 4.02Å; Q310-V313 PolarHBondContact O-N 2.88Å; P311-V313 VanDerWaalsContact C-N 3.33Å; P311-V313 PolarHBondContact O-N 3.25Å; V313-V316 WeakPolarHBondContact O-CB 3.33Å; V313-V316 PolarHBondContact O-N 2.66Å; V313-F317 HydrophobicContact CG1-CD1 3.85Å; V313-F317 HydrophobicContact CG1-CE1 3.66Å; V313-F317 HydrophobicContact CG1-CZ 4.49Å; V313-F317 WeakPolarHBondContact O-CD1 3.34Å; V313-F317 PolarHBondContact O-N 2.64Å; V313-F345 HydrophobicContact CG1-CD1 4.37Å; V313-F345 HydrophobicContact CG1-CE1 3.77Å; V313-F345 HydrophobicContact CG1-CZ 4.09Å; V313-F345 HydrophobicContact CG2-CE1 4.05Å; V313-F345 HydrophobicContact CG2-CZ 4Å; V313-V362 HydrophobicContact CG2-CB 3.92Å; V313-V362 HydrophobicContact CG2-CG1 4.35Å; V313-V362 HydrophobicContact CG2-CG2 3.65Å
314	Q	98.3	Very high	96.7	Very high	35 Å²	35	28.8 Å²	28.8	16%	0.164	15%	0.154	C	C	.	.	H	α-helix	trans	-63	-44	176.1	-67	-174.5	-0.4	0	0	111.9	I298 F308 Q310 P311 V316 F317 E318	I298-Q314 HydrophobicContact CG2-CB 3.59Å; I298-Q314 HydrophobicContact CG2-CG 3.7Å; F308-Q314 WeakPolarHBondContact O-CG 3.44Å; F308-Q314 PolarHBondContact O-NE2 2.9Å; Q310-Q314 PolarHBondContact O-N 3.44Å; P311-Q314 PolarHBondContact O-N 3.42Å; Q314-V316 PolarHBondContact O-N 3.13Å; Q314-F317 PolarHBondContact O-N 2.76Å; Q314-E318 WeakPolarHBondContact O-CG 3.38Å; Q314-E318 PolarHBondContact O-N 2.87Å
315	E	97.6	Very high	97.2	Very high	105 Å²	105	24.3 Å²	24.3	49%	0.491	13%	0.131	S	C	.	.	H	α-helix	trans	-63.2	-39.6	174.3	-73.2	-170.3	-163.6	0	0	113.3	P311 F317 E318 R319	P311-E315 PolarHBondContact O-N 2.87Å; E315-F317 VanDerWaalsContact C-N 3.32Å; E315-F317 PolarHBondContact O-N 2.75Å; E315-E318 PolarHBondContact O-N 3.38Å; E315-R319 WeakPolarHBondContact O-CG 3.31Å; E315-R319 PolarHBondContact O-N 3.49Å; E315-R319 IonicContact OE2-NH1 3.89Å; E315-R319 PolarHBondContact OE2-NH1 3.35Å
316	V	98.4	Very high	97.5	Very high	3 Å²	3	25.7 Å²	25.7	2%	0.018	14%	0.138	C	C	.	.	H	α-helix	trans	-57.7	-47.1	173.5	161.8	0	0	0	0	110.2	A312 V313 Q314 R319 I320 F345 E374	A312-V316 VanDerWaalsContact O-CG2 3.26Å; A312-V316 WeakPolarHBondContact O-CG2 3.37Å; A312-V316 PolarHBondContact O-N 2.72Å; A312-V316 VanDerWaalsContact O-N 3.1Å; V313-V316 WeakPolarHBondContact O-CB 3.33Å; V313-V316 PolarHBondContact O-N 2.66Å; Q314-V316 PolarHBondContact O-N 3.13Å; V316-R319 VanDerWaalsContact CG2-NH2 3.33Å; V316-R319 PolarHBondContact O-N 2.86Å; V316-I320 HydrophobicContact CG1-CD1 3.73Å; V316-I320 VanDerWaalsContact O-CG1 3.3Å; V316-I320 WeakPolarHBondContact O-CG1 3.39Å; V316-I320 PolarHBondContact O-N 2.74Å; V316-F345 HydrophobicContact CG1-CD2 4.09Å; V316-F345 HydrophobicContact CG1-CE2 3.82Å; V316-E374 HydrophobicContact CG1-CB 3.98Å; V316-E374 HydrophobicContact CG1-CG 3.91Å; V316-E374 HydrophobicContact CG2-CB 4.46Å
317	F	98.7	Very high	97.7	Very high	4 Å²	4	27.9 Å²	27.9	2%	0.018	14%	0.138	C	C	.	.	H	α-helix	trans	-68.9	-39.2	-178.8	-84.7	54.8	0	0	0	112.3	I298 F308 V313 Q314 E315 I320 L321 V341 T342 F345	I298-F317 HydrophobicContact CD1-CB 3.64Å; I298-F317 HydrophobicContact CD1-CD2 4Å; I298-F317 HydrophobicContact CD1-CG 4.32Å; I298-F317 HydrophobicContact CG1-CB 4.16Å; I298-F317 HydrophobicContact CG2-CB 4.35Å; F308-F317 HydrophobicContact CD1-CE1 4.44Å; F308-F317 HydrophobicContact CD1-CE2 4.35Å; F308-F317 AromaticContact CD1-CZ 3.92Å; F308-F317 HydrophobicContact CD1-CZ 3.92Å; F308-F317 HydrophobicContact CE1-CE1 4.47Å; F308-F317 HydrophobicContact CE1-CE2 4.38Å; F308-F317 AromaticContact CE1-CZ 3.75Å; F308-F317 HydrophobicContact CE1-CZ 3.75Å; V313-F317 HydrophobicContact CG1-CD1 3.85Å; V313-F317 HydrophobicContact CG1-CE1 3.66Å; V313-F317 HydrophobicContact CG1-CZ 4.49Å; V313-F317 WeakPolarHBondContact O-CD1 3.34Å; V313-F317 PolarHBondContact O-N 2.64Å; Q314-F317 PolarHBondContact O-N 2.76Å; E315-F317 VanDerWaalsContact C-N 3.32Å; E315-F317 PolarHBondContact O-N 2.75Å; F317-I320 PolarHBondContact O-N 3.39Å; F317-L321 WeakPolarHBondContact O-CB 3.48Å; F317-L321 WeakPolarHBondContact O-CG 3.31Å; F317-L321 PolarHBondContact O-N 3.05Å; F317-V341 HydrophobicContact CD1-CG1 4.15Å; F317-V341 HydrophobicContact CD2-CB 3.87Å; F317-V341 HydrophobicContact CD2-CG1 3.79Å; F317-V341 HydrophobicContact CD2-CG2 4.37Å; F317-V341 HydrophobicContact CE1-CG1 3.93Å; F317-V341 HydrophobicContact CE2-CB 3.56Å; F317-V341 HydrophobicContact CE2-CG1 3.53Å; F317-V341 HydrophobicContact CE2-CG2 4.5Å; F317-V341 HydrophobicContact CG-CG1 4.1Å; F317-V341 HydrophobicContact CZ-CB 4.09Å; F317-V341 HydrophobicContact CZ-CG1 3.62Å; F317-T342 HydrophobicContact CE2-CG2 3.57Å; F317-T342 HydrophobicContact CZ-CG2 4.05Å; F317-F345 HydrophobicContact CE1-CB 3.89Å; F317-F345 AromaticContact CE1-CD1 3.78Å; F317-F345 HydrophobicContact CE1-CD1 3.78Å; F317-F345 AromaticContact CE1-CD2 3.96Å; F317-F345 HydrophobicContact CE1-CD2 3.96Å; F317-F345 HydrophobicContact CE1-CE1 4.31Å; F317-F345 HydrophobicContact CE1-CE2 4.48Å; F317-F345 AromaticContact CE1-CG 3.58Å; F317-F345 HydrophobicContact CE1-CG 3.58Å; F317-F345 HydrophobicContact CZ-CB 3.91Å; F317-F345 HydrophobicContact CZ-CD1 4.19Å; F317-F345 HydrophobicContact CZ-CG 4.05Å
318	E	98.4	Very high	97.8	Very high	14 Å²	14	30.1 Å²	30.1	7%	0.065	15%	0.148	C	C	.	.	H	α-helix	trans	-57.6	-46.4	171.1	-78.8	-173.7	-172.2	0	0	111.8	Y279 Y291 I294 H295 I298 Q314 E315 F322	Y279-E318 PolarHBondContact OH-OE2 2.77Å; Y291-E318 HydrophobicContact CE2-CB 4.24Å; Y291-E318 HydrophobicContact CE2-CG 4.28Å; Y291-E318 WeakPolarHBondContact CE2-OE2 3.45Å; Y291-E318 VanDerWaalsContact CZ-OE2 3.25Å; Y291-E318 PolarHBondContact OH-OE2 3.31Å; I294-E318 HydrophobicContact CG2-CB 4.47Å; I294-E318 HydrophobicContact CG2-CG 4.15Å; H295-E318 IonicContact CE1-OE1 3.41Å; H295-E318 IonicContact CG-OE1 3.91Å; H295-E318 IonicContact ND1-OE1 3.31Å; H295-E318 PolarHBondContact ND1-OE1 2.96Å; I298-E318 HydrophobicContact CG1-CG 4.3Å; Q314-E318 WeakPolarHBondContact O-CG 3.38Å; Q314-E318 PolarHBondContact O-N 2.87Å; E315-E318 PolarHBondContact O-N 3.38Å; E318-F322 WeakPolarHBondContact O-CB 3.41Å; E318-F322 PolarHBondContact O-N 3.5Å
319	R	98.6	Very high	97.8	Very high	41 Å²	41	35.4 Å²	35.4	16%	0.155	18%	0.183	C	C	.	.	H	α-helix	trans	-61.6	-51.9	176.7	-74.5	-172.4	-60.4	-96.8	5.5	111.9	Y279 E315 V316 L321 F322 I323 E374	Y279-R319 HydrophobicContact CD1-CG 3.91Å; Y279-R319 HydrophobicContact CD2-CG 3.89Å; Y279-R319 HydrophobicContact CE1-CG 3.59Å; Y279-R319 HydrophobicContact CE2-CB 4.26Å; Y279-R319 HydrophobicContact CE2-CG 3.58Å; Y279-R319 HydrophobicContact CG-CG 4.06Å; Y279-R319 VanDerWaalsContact CZ-CG 3.42Å; E315-R319 WeakPolarHBondContact O-CG 3.31Å; E315-R319 PolarHBondContact O-N 3.49Å; E315-R319 IonicContact OE2-NH1 3.89Å; E315-R319 PolarHBondContact OE2-NH1 3.35Å; V316-R319 VanDerWaalsContact CG2-NH2 3.33Å; V316-R319 PolarHBondContact O-N 2.86Å; R319-L321 PolarHBondContact O-N 2.85Å; R319-F322 PolarHBondContact O-N 3Å; R319-I323 WeakPolarHBondContact O-CB 3.33Å; R319-I323 VanDerWaalsContact O-CG1 3.25Å; R319-I323 WeakPolarHBondContact O-CG1 3.5Å; R319-I323 PolarHBondContact O-N 2.86Å; R319-E374 VanDerWaalsContact CB-OE1 3.29Å; R319-E374 WeakPolarHBondContact CB-OE1 3.32Å; R319-E374 WeakPolarHBondContact CD-OE1 3.26Å; R319-E374 IonicContact CZ-OE1 2.65Å; R319-E374 IonicContact CZ-OE2 3.63Å; R319-E374 IonicContact NE-OE1 2.74Å; R319-E374 PolarHBondContact NE-OE1 2.94Å; R319-E374 IonicContact NE-OE2 3.73Å; R319-E374 PolarHBondContact NE-OE2 3.43Å; R319-E374 VanDerWaalsContact NE-OE2 3.15Å; R319-E374 IonicContact NH2-OE1 2.94Å; R319-E374 IonicContact NH2-OE2 2.68Å; R319-E374 PolarHBondContact NH2-OE2 2.9Å
320	I	98.8	Very high	97.8	Very high	0 Å²	0	35 Å²	35	0%	0	19%	0.194	C	C	.	.	H	α-helix	trans	-55.5	-51.5	-179.3	-69.7	168.6	0	0	0	110.9	V316 F317 W324 V341 E374 F378 M381	V316-I320 HydrophobicContact CG1-CD1 3.73Å; V316-I320 VanDerWaalsContact O-CG1 3.3Å; V316-I320 WeakPolarHBondContact O-CG1 3.39Å; V316-I320 PolarHBondContact O-N 2.74Å; F317-I320 PolarHBondContact O-N 3.39Å; I320-W324 WeakPolarHBondContact O-CB 3.24Å; I320-W324 PolarHBondContact O-N 2.84Å; I320-V341 HydrophobicContact CD1-CG1 3.9Å; I320-V341 HydrophobicContact CG2-CG1 4.28Å; I320-V341 HydrophobicContact CG2-CG2 4.08Å; I320-E374 HydrophobicContact CD1-CG 4.1Å; I320-E374 HydrophobicContact CG1-CG 3.93Å; I320-F378 HydrophobicContact CG1-CB 4.32Å; I320-F378 HydrophobicContact CG2-CB 4.31Å; I320-F378 HydrophobicContact CG2-CD2 4.36Å; I320-M381 HydrophobicContact CG2-CE 3.81Å; I320-M381 HydrophobicContact CG2-SD 4.11Å
321	L	98.7	Very high	97.8	Very high	1 Å²	1	34.9 Å²	34.9	1%	0.005	20%	0.196	C	C	.	.	H	α-helix	trans	-71.6	-37.7	-176.3	-67.8	166.3	0	0	0	112.5	I294 I298 F317 R319 W324 A325 Y333 I337 N338 V341 M381	I294-L321 HydrophobicContact CD1-CB 4.01Å; I294-L321 HydrophobicContact CG1-CB 4.27Å; I294-L321 HydrophobicContact CG2-CB 4.01Å; I294-L321 HydrophobicContact CG2-CD1 4.01Å; I298-L321 HydrophobicContact CD1-CD1 3.57Å; I298-L321 HydrophobicContact CG1-CD1 4.19Å; F317-L321 WeakPolarHBondContact O-CB 3.48Å; F317-L321 WeakPolarHBondContact O-CG 3.31Å; F317-L321 PolarHBondContact O-N 3.05Å; R319-L321 PolarHBondContact O-N 2.85Å; L321-W324 PolarHBondContact O-N 3.4Å; L321-A325 WeakPolarHBondContact O-CB 3.4Å; L321-A325 PolarHBondContact O-N 2.91Å; L321-Y333 HydrophobicContact CD1-CE2 4.21Å; L321-Y333 HydrophobicContact CD2-CE2 4.3Å; L321-I337 HydrophobicContact CD2-CB 4.35Å; L321-I337 HydrophobicContact CD2-CG2 3.77Å; L321-N338 HydrophobicContact CD1-CB 3.71Å; L321-V341 HydrophobicContact CD1-CG2 4.49Å; L321-V341 HydrophobicContact CD2-CG2 3.77Å; L321-V341 HydrophobicContact CG-CG2 4.02Å; L321-M381 HydrophobicContact CD2-SD 4.42Å
322	F	98.6	Very high	97.7	Very high	0 Å²	0	31.3 Å²	31.3	0%	0	18%	0.176	C	C	.	.	H	α-helix	trans	-65	-49.7	177.8	-178.2	-93.2	0	0	0	110.9	Y278 Y279 R282 Y287 Y291 I294 E318 R319 W324 A325 I326	Y278-F322 WeakPolarHBondContact O-CE1 3.13Å; Y279-F322 HydrophobicContact CD2-CB 4.4Å; Y279-F322 AromaticContact CD2-CD1 3.83Å; Y279-F322 HydrophobicContact CD2-CD1 3.83Å; Y279-F322 HydrophobicContact CD2-CG 4.3Å; Y279-F322 HydrophobicContact CE2-CB 4.23Å; Y279-F322 HydrophobicContact CE2-CD1 4.38Å; Y279-F322 HydrophobicContact CE2-CG 4.4Å; R282-F322 VanDerWaalsContact CA-CZ 3.43Å; R282-F322 HydrophobicContact CB-CD1 4.26Å; R282-F322 HydrophobicContact CB-CD2 4.01Å; R282-F322 HydrophobicContact CB-CE1 3.82Å; R282-F322 HydrophobicContact CB-CE2 3.54Å; R282-F322 HydrophobicContact CB-CG 4.35Å; R282-F322 HydrophobicContact CB-CZ 3.46Å; R282-F322 VanDerWaalsContact CB-CZ 3.46Å; Y287-F322 HydrophobicContact CD2-CZ 4.34Å; Y287-F322 HydrophobicContact CG-CZ 4.08Å; Y291-F322 HydrophobicContact CD2-CD2 4.14Å; Y291-F322 HydrophobicContact CG-CD2 4.41Å; I294-F322 HydrophobicContact CD1-CB 4.12Å; I294-F322 HydrophobicContact CD1-CD2 4.48Å; E318-F322 WeakPolarHBondContact O-CB 3.41Å; E318-F322 PolarHBondContact O-N 3.5Å; R319-F322 PolarHBondContact O-N 3Å; F322-W324 VanDerWaalsContact C-N 3.29Å; F322-W324 PolarHBondContact O-N 2.86Å; F322-A325 PolarHBondContact O-N 2.95Å; F322-I326 HydrophobicContact CD1-CD1 4.19Å; F322-I326 HydrophobicContact CD1-CG2 4.48Å; F322-I326 HydrophobicContact CE1-CD1 3.81Å; F322-I326 HydrophobicContact CE1-CG2 4.01Å; F322-I326 HydrophobicContact CE2-CG2 4.14Å; F322-I326 HydrophobicContact CZ-CG2 3.79Å; F322-I326 WeakPolarHBondContact O-CG1 3.27Å; F322-I326 PolarHBondContact O-N 3.07Å; F322-I326 VanDerWaalsContact O-N 3.11Å
323	I	98.5	Very high	97.8	Very high	0 Å²	0	30.7 Å²	30.7	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-64.1	-33.9	178	-63.7	-60.5	0	0	0	111.3	Y271 F274 I275 Y278 R319 I326 R327 F378	Y271-I323 HydrophobicContact CD2-CG2 4.42Å; Y271-I323 HydrophobicContact CE2-CB 4.35Å; Y271-I323 HydrophobicContact CE2-CG2 4.1Å; F274-I323 HydrophobicContact CB-CD1 4.33Å; F274-I323 HydrophobicContact CB-CG2 3.66Å; F274-I323 HydrophobicContact CD2-CG2 3.97Å; F274-I323 HydrophobicContact CG-CG2 4.28Å; F274-I323 WeakPolarHBondContact O-CD1 3.15Å; I275-I323 HydrophobicContact CG1-CG1 4.19Å; Y278-I323 HydrophobicContact CD2-CD1 4.42Å; R319-I323 WeakPolarHBondContact O-CB 3.33Å; R319-I323 VanDerWaalsContact O-CG1 3.25Å; R319-I323 WeakPolarHBondContact O-CG1 3.5Å; R319-I323 PolarHBondContact O-N 2.86Å; I323-I326 HydrophobicContact CD1-CD1 4.05Å; I323-R327 WeakPolarHBondContact O-CB 3.48Å; I323-R327 VanDerWaalsContact O-CG 3.22Å; I323-R327 WeakPolarHBondContact O-CG 3.39Å; I323-F378 HydrophobicContact CB-CE2 4.36Å; I323-F378 HydrophobicContact CG2-CD2 4.5Å; I323-F378 HydrophobicContact CG2-CE2 3.81Å; I323-F378 HydrophobicContact CG2-CZ 4.1Å
324	W	98.6	Very high	97.8	Very high	5 Å²	5	31.8 Å²	31.8	2%	0.019	17%	0.174	C	C	.	.	H	α-helix	trans	-68	-50.2	172.4	-170.7	88.4	0	0	0	111.9	I320 L321 F322 I326 R327 H328 G332 I337 F378 M381 L385	I320-W324 WeakPolarHBondContact O-CB 3.24Å; I320-W324 PolarHBondContact O-N 2.84Å; L321-W324 PolarHBondContact O-N 3.4Å; F322-W324 VanDerWaalsContact C-N 3.29Å; F322-W324 PolarHBondContact O-N 2.86Å; W324-I326 PolarHBondContact O-N 2.89Å; W324-R327 PolarHBondContact O-N 3.15Å; W324-R327 VanDerWaalsContact O-N 3.14Å; W324-H328 AromaticContact CD1-CE1 3.44Å; W324-H328 VanDerWaalsContact CD1-CE1 3.44Å; W324-H328 AromaticContact CD1-ND1 3.55Å; W324-H328 AromaticContact CD2-ND1 3.55Å; W324-H328 AromaticContact CE2-CE1 3.64Å; W324-H328 AromaticContact CE2-CG 3.71Å; W324-H328 AromaticContact CE2-ND1 3.29Å; W324-H328 VanDerWaalsContact CE2-ND1 3.29Å; W324-H328 AromaticContact CG-ND1 3.69Å; W324-H328 HydrophobicContact CH2-CB 4.03Å; W324-H328 HydrophobicContact CZ2-CB 4.03Å; W324-H328 AromaticContact CZ2-CG 3.72Å; W324-H328 AromaticContact CZ2-ND1 3.81Å; W324-H328 HydrophobicContact CZ3-CB 4.29Å; W324-H328 AromaticContact NE1-CE1 3.17Å; W324-H328 PolarHBondContact NE1-CE1 2.95Å; W324-H328 AromaticContact NE1-ND1 3.31Å; W324-H328 PolarHBondContact NE1-ND1 3.49Å; W324-H328 AromaticContact NE1-NE2 3.84Å; W324-H328 PolarHBondContact O-N 2.89Å; W324-H328 VanDerWaalsContact O-N 3.13Å; W324-H328 PolarHBondContact O-ND1 3.16Å; W324-G332 WeakPolarHBondContact CZ3-O 3.47Å; W324-I337 HydrophobicContact CE3-CD1 4.33Å; W324-I337 HydrophobicContact CH2-CD1 4.04Å; W324-I337 HydrophobicContact CZ3-CD1 3.58Å; W324-F378 HydrophobicContact CB-CE2 4.07Å; W324-M381 HydrophobicContact CB-CE 3.77Å; W324-M381 HydrophobicContact CD2-CE 4.41Å; W324-M381 HydrophobicContact CG-CE 3.63Å; W324-L385 HydrophobicContact CD2-CD1 3.98Å; W324-L385 VanDerWaalsContact CE2-CD1 3.43Å; W324-L385 HydrophobicContact CG-CD1 4.46Å; W324-L385 HydrophobicContact CH2-CD1 4.28Å; W324-L385 HydrophobicContact CZ2-CB 3.9Å; W324-L385 HydrophobicContact CZ2-CD1 3.63Å; W324-L385 HydrophobicContact CZ2-CG 4.24Å
325	A	97.9	Very high	97.6	Very high	2 Å²	2	34.1 Å²	34.1	2%	0.017	19%	0.185	C	C	.	.	H	α-helix	trans	-59.6	-45	-175.1	0	0	0	0	0	113.2	T290 L321 F322 R327 H328	T290-A325 HydrophobicContact CG2-CB 3.8Å; L321-A325 WeakPolarHBondContact O-CB 3.4Å; L321-A325 PolarHBondContact O-N 2.91Å; F322-A325 PolarHBondContact O-N 2.95Å; A325-R327 VanDerWaalsContact C-N 3.29Å; A325-R327 PolarHBondContact O-N 3.46Å; A325-H328 CarbonylContact O-C 3.41Å; A325-H328 PolarHBondContact O-N 3.4Å
326	I	96.6	Very high	97.4	Very high	30 Å²	30	29.1 Å²	29.1	15%	0.154	16%	0.162	C	C	.	.	H	α-helix	trans	-68.6	-27.6	178.8	66.7	-176.2	0	0	0	112.9	Y278 Y287 F322 I323 W324	Y278-I326 HydrophobicContact CD1-CD1 3.96Å; Y278-I326 HydrophobicContact CD2-CD1 3.88Å; Y278-I326 HydrophobicContact CG-CD1 3.46Å; Y278-I326 VanDerWaalsContact CG-CD1 3.46Å; Y287-I326 HydrophobicContact CD1-CG2 3.87Å; Y287-I326 HydrophobicContact CE1-CG2 3.99Å; Y287-I326 HydrophobicContact CG-CG2 4.46Å; F322-I326 HydrophobicContact CD1-CD1 4.19Å; F322-I326 HydrophobicContact CD1-CG2 4.48Å; F322-I326 HydrophobicContact CE1-CD1 3.81Å; F322-I326 HydrophobicContact CE1-CG2 4.01Å; F322-I326 HydrophobicContact CE2-CG2 4.14Å; F322-I326 HydrophobicContact CZ-CG2 3.79Å; F322-I326 WeakPolarHBondContact O-CG1 3.27Å; F322-I326 PolarHBondContact O-N 3.07Å; F322-I326 VanDerWaalsContact O-N 3.11Å; I323-I326 HydrophobicContact CD1-CD1 4.05Å; W324-I326 PolarHBondContact O-N 2.89Å
327	R	96.7	Very high	97.3	Very high	106 Å²	106	29 Å²	29	40%	0.4	16%	0.161	S	C	.	.	H	α-helix	trans	-81.9	-15.5	178	-70.8	-173	69.4	84.2	9.5	113.1	I323 W324 A325 P329	I323-R327 WeakPolarHBondContact O-CB 3.48Å; I323-R327 VanDerWaalsContact O-CG 3.22Å; I323-R327 WeakPolarHBondContact O-CG 3.39Å; W324-R327 PolarHBondContact O-N 3.15Å; W324-R327 VanDerWaalsContact O-N 3.14Å; A325-R327 VanDerWaalsContact C-N 3.29Å; A325-R327 PolarHBondContact O-N 3.46Å; R327-P329 VanDerWaalsContact O-CD 3.3Å; R327-P329 WeakPolarHBondContact O-CD 3.33Å
328	H	97.4	Very high	97.3	Very high	47 Å²	47	29 Å²	29	22%	0.218	16%	0.162	C	C	.	.			trans	-120.3	62.7	178.4	-56.6	88.6	0	0	0	111.1	W324 A325 A330 S331 G332	W324-H328 AromaticContact CD1-CE1 3.44Å; W324-H328 VanDerWaalsContact CD1-CE1 3.44Å; W324-H328 AromaticContact CD1-ND1 3.55Å; W324-H328 AromaticContact CD2-ND1 3.55Å; W324-H328 AromaticContact CE2-CE1 3.64Å; W324-H328 AromaticContact CE2-CG 3.71Å; W324-H328 AromaticContact CE2-ND1 3.29Å; W324-H328 VanDerWaalsContact CE2-ND1 3.29Å; W324-H328 AromaticContact CG-ND1 3.69Å; W324-H328 HydrophobicContact CH2-CB 4.03Å; W324-H328 HydrophobicContact CZ2-CB 4.03Å; W324-H328 AromaticContact CZ2-CG 3.72Å; W324-H328 AromaticContact CZ2-ND1 3.81Å; W324-H328 HydrophobicContact CZ3-CB 4.29Å; W324-H328 AromaticContact NE1-CE1 3.17Å; W324-H328 PolarHBondContact NE1-CE1 2.95Å; W324-H328 AromaticContact NE1-ND1 3.31Å; W324-H328 PolarHBondContact NE1-ND1 3.49Å; W324-H328 AromaticContact NE1-NE2 3.84Å; W324-H328 PolarHBondContact O-N 2.89Å; W324-H328 VanDerWaalsContact O-N 3.13Å; W324-H328 PolarHBondContact O-ND1 3.16Å; A325-H328 CarbonylContact O-C 3.41Å; A325-H328 PolarHBondContact O-N 3.4Å; H328-A330 PolarHBondContact O-N 2.89Å; H328-S331 PolarHBondContact O-N 2.59Å; H328-G332 PolarHBondContact O-N 3.32Å
329	P	96.1	Very high	97.2	Very high	115 Å²	115	28.4 Å²	28.4	75%	0.747	16%	0.159	S	C	*	.	T	Hydrogen-bonded Turn	trans	-66.4	-8.7	-171.2	28.4	-37.5	0	0	0	115.1	R327 S331	R327-P329 VanDerWaalsContact O-CD 3.3Å; R327-P329 WeakPolarHBondContact O-CD 3.33Å; P329-S331 VanDerWaalsContact C-N 3.25Å
330	A	95.9	Very high	97.2	Very high	74 Å²	74	26.4 Å²	26.4	61%	0.612	15%	0.151	S	C	*	.	T	Hydrogen-bonded Turn	trans	-73.2	-18.3	169.4	0	0	0	0	0	113.3	H328 T393	H328-A330 PolarHBondContact O-N 2.89Å; A330-T393 HydrophobicContact CB-CG2 4.26Å; A330-T393 WeakPolarHBondContact O-CA 3.34Å
331	S	97.3	Very high	97.1	Very high	25 Å²	25	26.4 Å²	26.4	18%	0.175	15%	0.151	C	C	.	.	T	Hydrogen-bonded Turn	trans	-118.6	-43.8	-179.7	-52.6	0	0	0	0	111.8	H328 P329 Y392	H328-S331 PolarHBondContact O-N 2.59Å; P329-S331 VanDerWaalsContact C-N 3.25Å; S331-Y392 VanDerWaalsContact CA-O 3.28Å; S331-Y392 WeakPolarHBondContact CA-O 3.39Å; S331-Y392 WeakPolarHBondContact CB-O 3.12Å; S331-Y392 PolarHBondContact OG-O 3.15Å
332	G	96.6	Very high	97.1	Very high	18 Å²	18	26.4 Å²	26.4	19%	0.186	15%	0.151	C	C	.	.			trans	67.1	-146.9	-170.8	0	0	0	0	0	111.4	W324 H328	W324-G332 WeakPolarHBondContact CZ3-O 3.47Å; H328-G332 PolarHBondContact O-N 3.32Å
333	Y	97.9	Very high	97	Very high	18 Å²	18	26.4 Å²	26.4	7%	0.071	15%	0.151	C	C	.	.			trans	-92.9	134.5	166.8	174.4	-106	0	0	0	109.8	Q293 I294 D297 L321 N338	Q293-Y333 HydrophobicContact CB-CD1 3.79Å; Q293-Y333 HydrophobicContact CB-CE1 4.03Å; I294-Y333 HydrophobicContact CD1-CD2 4.19Å; I294-Y333 HydrophobicContact CD1-CG 4.11Å; I294-Y333 HydrophobicContact CG1-CD1 3.78Å; I294-Y333 HydrophobicContact CG1-CD2 3.59Å; I294-Y333 HydrophobicContact CG1-CE1 4.13Å; I294-Y333 HydrophobicContact CG1-CE2 3.97Å; I294-Y333 HydrophobicContact CG1-CG 3.49Å; I294-Y333 VanDerWaalsContact CG1-CG 3.49Å; D297-Y333 WeakPolarHBondContact CB-OH 3.17Å; D297-Y333 VanDerWaalsContact OD2-CE1 3.3Å; D297-Y333 WeakPolarHBondContact OD2-CE1 3.32Å; D297-Y333 PolarHBondContact OD2-OH 3.37Å; L321-Y333 HydrophobicContact CD1-CE2 4.21Å; L321-Y333 HydrophobicContact CD2-CE2 4.3Å; Y333-N338 HydrophobicContact CE2-CB 4.38Å; Y333-N338 PolarHBondContact OH-OD1 2.98Å
334	V	97.5	Very high	97	Very high	25 Å²	25	26.4 Å²	26.4	15%	0.152	15%	0.151	C	C	.	.			trans	-129.1	133.2	175.1	-178.1	0	0	0	0	108.6	G336 I337 Y392	V334-G336 PolarHBondContact O-N 3.4Å; V334-I337 HydrophobicContact CB-CD1 3.97Å; V334-I337 HydrophobicContact CB-CG1 4.43Å; V334-I337 WeakPolarHBondContact O-CG1 3.45Å; V334-I337 PolarHBondContact O-N 2.93Å; V334-Y392 HydrophobicContact CB-CD1 4.15Å; V334-Y392 HydrophobicContact CG1-CD1 4.17Å; V334-Y392 WeakPolarHBondContact CG2-O 3.3Å
335	Q	95.7	Very high	97	Very high	83 Å²	83	26.3 Å²	26.3	39%	0.388	15%	0.151	S	C	.	.	T	Hydrogen-bonded Turn	trans	-58.6	127.6	-179.7	-174.2	-178.1	2.6	0	0	110.9	D297 N437	D297-Q335 WeakPolarHBondContact OD2-CG 3.32Å; Q335-N437 PolarHBondContact O-ND2 2.99Å
336	G	93	Very high	97	Very high	1 Å²	1	26.4 Å²	26.4	1%	0.01	15%	0.151	C	C	.	.	T	Hydrogen-bonded Turn	trans	112.9	-27.2	-174.9	0	0	0	0	0	113.6	V334 N338 D339 N438	V334-G336 PolarHBondContact O-N 3.4Å; G336-N338 WeakPolarHBondContact CA-OD1 3.19Å; G336-N338 PolarHBondContact N-OD1 3.38Å; G336-N338 PolarHBondContact O-N 2.95Å; G336-D339 WeakPolarHBondContact O-CB 3.33Å; G336-D339 PolarHBondContact O-N 3.08Å; G336-N438 WeakPolarHBondContact CA-ND2 3.48Å
337	I	96.6	Very high	97	Very high	0 Å²	0	25 Å²	25	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-62.7	-29.6	172.7	-58.3	177.3	0	0	0	110.6	L321 W324 V334 D339 L340 M381 L385 Y392	L321-I337 HydrophobicContact CD2-CB 4.35Å; L321-I337 HydrophobicContact CD2-CG2 3.77Å; W324-I337 HydrophobicContact CE3-CD1 4.33Å; W324-I337 HydrophobicContact CH2-CD1 4.04Å; W324-I337 HydrophobicContact CZ3-CD1 3.58Å; V334-I337 HydrophobicContact CB-CD1 3.97Å; V334-I337 HydrophobicContact CB-CG1 4.43Å; V334-I337 WeakPolarHBondContact O-CG1 3.45Å; V334-I337 PolarHBondContact O-N 2.93Å; I337-D339 PolarHBondContact O-N 2.76Å; I337-L340 WeakPolarHBondContact O-CB 3.21Å; I337-L340 PolarHBondContact O-N 3.44Å; I337-L340 VanDerWaalsContact O-N 3.09Å; I337-M381 HydrophobicContact CG2-SD 4.37Å; I337-L385 HydrophobicContact CG2-CD1 3.91Å; I337-Y392 HydrophobicContact CD1-CD1 3.78Å; I337-Y392 HydrophobicContact CD1-CD2 4.31Å; I337-Y392 HydrophobicContact CD1-CE1 4.36Å; I337-Y392 HydrophobicContact CD1-CG 3.76Å; I337-Y392 HydrophobicContact CG1-CD1 3.72Å; I337-Y392 HydrophobicContact CG1-CE1 3.8Å; I337-Y392 HydrophobicContact CG1-CG 4.12Å
338	N	97.2	Very high	97.1	Very high	5 Å²	5	20 Å²	20	3%	0.027	13%	0.125	C	C	.	.	H	α-helix	trans	-56.6	-31.9	172.5	63	-66.5	0	0	0	114.1	I298 T301 L321 Y333 G336	I298-N338 HydrophobicContact CD1-CB 4.05Å; T301-N338 PolarHBondContact OG1-ND2 2.78Å; L321-N338 HydrophobicContact CD1-CB 3.71Å; Y333-N338 HydrophobicContact CE2-CB 4.38Å; Y333-N338 PolarHBondContact OH-OD1 2.98Å; G336-N338 WeakPolarHBondContact CA-OD1 3.19Å; G336-N338 PolarHBondContact N-OD1 3.38Å; G336-N338 PolarHBondContact O-N 2.95Å
339	D	97.1	Very high	97.1	Very high	0 Å²	0	17.8 Å²	17.8	0%	0	12%	0.115	C	C	.	.	H	α-helix	trans	-73.3	-35.8	177.1	-61	-38	0	0	0	111.1	G336 I337 V341 T342 N438 M441 R442	G336-D339 WeakPolarHBondContact O-CB 3.33Å; G336-D339 PolarHBondContact O-N 3.08Å; I337-D339 PolarHBondContact O-N 2.76Å; D339-V341 PolarHBondContact O-N 3.37Å; D339-T342 WeakPolarHBondContact O-CB 3.45Å; D339-T342 WeakPolarHBondContact O-CG2 3.45Å; D339-T342 PolarHBondContact O-N 2.88Å; D339-T342 PolarHBondContact O-OG1 3.26Å; D339-N438 PolarHBondContact OD2-ND2 3.21Å; D339-M441 HydrophobicContact CB-CE 4.22Å; D339-M441 HydrophobicContact CB-SD 4.38Å; D339-M441 WeakPolarHBondContact O-CE 3.32Å; D339-R442 IonicContact OD1-CZ 3.01Å; D339-R442 IonicContact OD1-NE 2.74Å; D339-R442 PolarHBondContact OD1-NE 3.27Å; D339-R442 IonicContact OD1-NH2 3.88Å; D339-R442 PolarHBondContact OD1-NH2 3Å; D339-R442 IonicContact OD2-CZ 2.69Å; D339-R442 VanDerWaalsContact OD2-CZ 3.26Å; D339-R442 IonicContact OD2-NE 2.67Å; D339-R442 PolarHBondContact OD2-NE 3.26Å; D339-R442 IonicContact OD2-NH2 3.29Å; D339-R442 PolarHBondContact OD2-NH2 3.42Å
340	L	97.8	Very high	97	Very high	0 Å²	0	12.9 Å²	12.9	0%	0	8%	0.084	C	C	.	.	H	α-helix	trans	-67.1	-17.9	-175.1	-54.3	177.7	0	0	0	113.5	I337 T342 P343 F344 L385 L439 M441 W453	I337-L340 WeakPolarHBondContact O-CB 3.21Å; I337-L340 PolarHBondContact O-N 3.44Å; I337-L340 VanDerWaalsContact O-N 3.09Å; L340-T342 VanDerWaalsContact C-N 3.34Å; L340-P343 WeakPolarHBondContact O-CD 3.07Å; L340-F344 WeakPolarHBondContact O-CD2 3.28Å; L340-L385 HydrophobicContact CD1-CD2 3.77Å; L340-L439 HydrophobicContact CD2-CB 4.4Å; L340-L439 HydrophobicContact CD2-CD1 4.07Å; L340-L439 HydrophobicContact CD2-CG 4.15Å; L340-M441 HydrophobicContact CD2-SD 3.88Å; L340-W453 HydrophobicContact CB-CH2 4.21Å; L340-W453 HydrophobicContact CD2-CH2 3.85Å; L340-W453 HydrophobicContact CD2-CZ2 3.88Å
341	V	98.3	Very high	96.8	Very high	0 Å²	0	13.2 Å²	13.2	0%	0	7%	0.072	C	C	.	.	H	α-helix	trans	-67.5	-36.3	169.9	-174.1	0	0	0	0	111	F317 I320 L321 D339 F344 F345 M381	F317-V341 HydrophobicContact CD1-CG1 4.15Å; F317-V341 HydrophobicContact CD2-CB 3.87Å; F317-V341 HydrophobicContact CD2-CG1 3.79Å; F317-V341 HydrophobicContact CD2-CG2 4.37Å; F317-V341 HydrophobicContact CE1-CG1 3.93Å; F317-V341 HydrophobicContact CE2-CB 3.56Å; F317-V341 HydrophobicContact CE2-CG1 3.53Å; F317-V341 HydrophobicContact CE2-CG2 4.5Å; F317-V341 HydrophobicContact CG-CG1 4.1Å; F317-V341 HydrophobicContact CZ-CB 4.09Å; F317-V341 HydrophobicContact CZ-CG1 3.62Å; I320-V341 HydrophobicContact CD1-CG1 3.9Å; I320-V341 HydrophobicContact CG2-CG1 4.28Å; I320-V341 HydrophobicContact CG2-CG2 4.08Å; L321-V341 HydrophobicContact CD1-CG2 4.49Å; L321-V341 HydrophobicContact CD2-CG2 3.77Å; L321-V341 HydrophobicContact CG-CG2 4.02Å; D339-V341 PolarHBondContact O-N 3.37Å; V341-F344 PolarHBondContact O-N 3.2Å; V341-F345 PolarHBondContact O-N 3.44Å; V341-M381 HydrophobicContact CB-SD 4.49Å; V341-M381 HydrophobicContact CG2-SD 3.52Å; V341-M381 VanDerWaalsContact CG2-SD 3.52Å
342	T	97.6	Very high	96.6	Very high	0 Å²	0	16.1 Å²	16.1	0%	0	8%	0.082	C	C	.	.	H	α-helix	trans	-61.2	-39	-164.8	66.3	0	0	0	0	115	T301 F308 F317 D339 L340 V346 M441	T301-T342 HydrophobicContact CG2-CG2 3.92Å; F308-T342 HydrophobicContact CD1-CG2 4.42Å; F308-T342 HydrophobicContact CE1-CG2 3.91Å; F308-T342 HydrophobicContact CZ-CG2 3.98Å; F317-T342 HydrophobicContact CE2-CG2 3.57Å; F317-T342 HydrophobicContact CZ-CG2 4.05Å; D339-T342 WeakPolarHBondContact O-CB 3.45Å; D339-T342 WeakPolarHBondContact O-CG2 3.45Å; D339-T342 PolarHBondContact O-N 2.88Å; D339-T342 PolarHBondContact O-OG1 3.26Å; L340-T342 VanDerWaalsContact C-N 3.34Å; T342-V346 WeakPolarHBondContact O-CB 3.35Å; T342-V346 VanDerWaalsContact O-CG2 3.23Å; T342-V346 WeakPolarHBondContact O-CG2 3.19Å; T342-V346 PolarHBondContact O-N 3.5Å; T342-V346 VanDerWaalsContact O-N 3.1Å; T342-M441 WeakPolarHBondContact OG1-CE 3.19Å
343	P	97.8	Very high	96.3	Very high	0 Å²	0	15.7 Å²	15.7	0%	0	8%	0.076	C	C	.	.	H	α-helix	trans	-73	-38.9	-178.6	-17.1	35	0	0	0	111.3	W246 L340 V347 M441 L446 T449 I450 W453	W246-P343 HydrophobicContact CH2-CB 3.96Å; W246-P343 HydrophobicContact CZ3-CB 4.11Å; L340-P343 WeakPolarHBondContact O-CD 3.07Å; P343-V347 WeakPolarHBondContact O-CB 3.36Å; P343-V347 VanDerWaalsContact O-CG2 3.28Å; P343-V347 WeakPolarHBondContact O-CG2 3.46Å; P343-V347 PolarHBondContact O-N 3.48Å; P343-M441 HydrophobicContact CG-CE 3.52Å; P343-M441 HydrophobicContact CG-SD 3.97Å; P343-L446 HydrophobicContact CB-CD1 4.46Å; P343-L446 HydrophobicContact CG-CD1 3.97Å; P343-T449 HydrophobicContact CB-CG2 4.36Å; P343-T449 HydrophobicContact CG-CG2 3.75Å; P343-I450 HydrophobicContact CB-CG1 3.97Å; P343-W453 HydrophobicContact CB-CD2 4.46Å; P343-W453 HydrophobicContact CB-CE3 3.78Å; P343-W453 HydrophobicContact CB-CZ3 3.81Å; P343-W453 HydrophobicContact CG-CD2 4.37Å; P343-W453 HydrophobicContact CG-CE3 3.85Å; P343-W453 HydrophobicContact CG-CH2 3.73Å; P343-W453 HydrophobicContact CG-CZ2 4.25Å; P343-W453 HydrophobicContact CG-CZ3 3.5Å; P343-W453 VanDerWaalsContact CG-CZ3 3.5Å
344	F	98.6	Very high	95.2	Very high	1 Å²	1	20.9 Å²	20.9	0%	0.004	11%	0.11	C	C	.	.	H	α-helix	trans	-64	-48.2	176.6	-65.4	-65.4	0	0	0	111.4	W246 L340 V341 V346 V347 F348 C380 M381 L384 W453	W246-F344 AromaticContact CE3-CD1 3.57Å; W246-F344 HydrophobicContact CE3-CD1 3.57Å; W246-F344 AromaticContact CE3-CE1 3.78Å; W246-F344 HydrophobicContact CE3-CE1 3.78Å; W246-F344 AromaticContact CZ3-CD1 3.69Å; W246-F344 HydrophobicContact CZ3-CD1 3.69Å; W246-F344 AromaticContact CZ3-CE1 3.92Å; W246-F344 HydrophobicContact CZ3-CE1 3.92Å; W246-F344 HydrophobicContact CZ3-CG 4.36Å; L340-F344 WeakPolarHBondContact O-CD2 3.28Å; V341-F344 PolarHBondContact O-N 3.2Å; F344-V346 VanDerWaalsContact C-N 3.34Å; F344-V346 PolarHBondContact O-N 2.99Å; F344-V347 PolarHBondContact O-N 3.31Å; F344-F348 HydrophobicContact CB-CD2 4.36Å; F344-F348 HydrophobicContact CB-CE2 4.01Å; F344-F348 HydrophobicContact CD1-CE2 4.27Å; F344-F348 HydrophobicContact CD1-CZ 4.37Å; F344-F348 WeakPolarHBondContact O-CD2 3.32Å; F344-F348 WeakPolarHBondContact O-CG 3.43Å; F344-F348 PolarHBondContact O-N 3.1Å; F344-C380 HydrophobicContact CD1-CB 3.5Å; F344-C380 VanDerWaalsContact CD1-CB 3.5Å; F344-C380 HydrophobicContact CE1-CB 3.61Å; F344-C380 HydrophobicContact CG-CB 4.13Å; F344-C380 HydrophobicContact CZ-CB 4.28Å; F344-M381 HydrophobicContact CD2-CB 3.93Å; F344-M381 HydrophobicContact CE2-CB 4.12Å; F344-L384 HydrophobicContact CE2-CB 4.12Å; F344-L384 HydrophobicContact CE2-CD2 3.91Å; F344-L384 HydrophobicContact CZ-CB 4.01Å; F344-L384 HydrophobicContact CZ-CD2 4.21Å; F344-W453 HydrophobicContact CD2-CZ3 4.03Å; F344-W453 HydrophobicContact CE2-CE3 4.19Å; F344-W453 HydrophobicContact CE2-CH2 4.4Å; F344-W453 AromaticContact CE2-CZ3 3.49Å; F344-W453 HydrophobicContact CE2-CZ3 3.49Å; F344-W453 VanDerWaalsContact CE2-CZ3 3.49Å; F344-W453 HydrophobicContact CZ-CE3 4.08Å; F344-W453 AromaticContact CZ-CZ3 3.84Å; F344-W453 HydrophobicContact CZ-CZ3 3.84Å
345	F	98.5	Very high	94	Very high	2 Å²	2	27.6 Å²	27.6	1%	0.009	14%	0.139	C	C	.	.	H	α-helix	trans	-58.8	-46.5	178.7	-176.9	-99.5	0	0	0	111.8	L307 F308 V313 V316 F317 V341 F348 L349 V362 I373 S377	L307-F345 HydrophobicContact CD1-CE1 4.4Å; L307-F345 HydrophobicContact CD2-CD1 4.36Å; L307-F345 HydrophobicContact CD2-CE1 4.18Å; L307-F345 HydrophobicContact CG-CE1 4.38Å; F308-F345 HydrophobicContact CE1-CD1 4.48Å; V313-F345 HydrophobicContact CG1-CD1 4.37Å; V313-F345 HydrophobicContact CG1-CE1 3.77Å; V313-F345 HydrophobicContact CG1-CZ 4.09Å; V313-F345 HydrophobicContact CG2-CE1 4.05Å; V313-F345 HydrophobicContact CG2-CZ 4Å; V316-F345 HydrophobicContact CG1-CD2 4.09Å; V316-F345 HydrophobicContact CG1-CE2 3.82Å; F317-F345 HydrophobicContact CE1-CB 3.89Å; F317-F345 AromaticContact CE1-CD1 3.78Å; F317-F345 HydrophobicContact CE1-CD1 3.78Å; F317-F345 AromaticContact CE1-CD2 3.96Å; F317-F345 HydrophobicContact CE1-CD2 3.96Å; F317-F345 HydrophobicContact CE1-CE1 4.31Å; F317-F345 HydrophobicContact CE1-CE2 4.48Å; F317-F345 AromaticContact CE1-CG 3.58Å; F317-F345 HydrophobicContact CE1-CG 3.58Å; F317-F345 HydrophobicContact CZ-CB 3.91Å; F317-F345 HydrophobicContact CZ-CD1 4.19Å; F317-F345 HydrophobicContact CZ-CG 4.05Å; V341-F345 PolarHBondContact O-N 3.44Å; F345-F348 PolarHBondContact O-N 2.88Å; F345-L349 HydrophobicContact CE1-CD2 4.05Å; F345-L349 WeakPolarHBondContact O-CB 3.01Å; F345-L349 PolarHBondContact O-N 3.47Å; F345-V362 HydrophobicContact CE1-CG2 4.43Å; F345-V362 HydrophobicContact CZ-CG1 4.33Å; F345-V362 HydrophobicContact CZ-CG2 4.21Å; F345-I373 HydrophobicContact CD2-CG2 3.61Å; F345-I373 HydrophobicContact CE2-CG2 3.6Å; F345-I373 HydrophobicContact CG-CG2 4.46Å; F345-I373 HydrophobicContact CZ-CG2 4.45Å; F345-S377 WeakPolarHBondContact CA-OG 3.3Å
346	V	97.3	Very high	93.4	Very high	4 Å²	4	26.9 Å²	26.9	2%	0.024	14%	0.138	C	C	.	.	H	α-helix	trans	-66.5	-41.4	179.4	166.3	0	0	0	0	112.2	I190 L307 F308 T342 F344 L349 S350 V357 L446 I450	I190-V346 HydrophobicContact CD1-CG1 4.15Å; I190-V346 HydrophobicContact CD1-CG2 3.73Å; I190-V346 HydrophobicContact CG2-CG1 3.5Å; L307-V346 HydrophobicContact CD2-CG2 3.88Å; F308-V346 HydrophobicContact CE1-CG2 4.25Å; F308-V346 HydrophobicContact CZ-CG2 3.76Å; T342-V346 WeakPolarHBondContact O-CB 3.35Å; T342-V346 VanDerWaalsContact O-CG2 3.23Å; T342-V346 WeakPolarHBondContact O-CG2 3.19Å; T342-V346 PolarHBondContact O-N 3.5Å; T342-V346 VanDerWaalsContact O-N 3.1Å; F344-V346 VanDerWaalsContact C-N 3.34Å; F344-V346 PolarHBondContact O-N 2.99Å; V346-L349 PolarHBondContact O-N 3.09Å; V346-S350 WeakPolarHBondContact O-CB 3.37Å; V346-S350 PolarHBondContact O-N 3.33Å; V346-V357 HydrophobicContact CG1-CG1 4.24Å; V346-L446 HydrophobicContact CB-CD2 4.37Å; V346-L446 HydrophobicContact CG1-CD2 4.44Å; V346-L446 HydrophobicContact CG2-CD2 3.88Å; V346-I450 HydrophobicContact CB-CD1 4.48Å; V346-I450 HydrophobicContact CG1-CD1 3.85Å
347	V	97.2	Very high	93.1	Very high	2 Å²	2	27.4 Å²	27.4	1%	0.012	14%	0.141	C	C	.	.	H	α-helix	trans	-64.2	-47.3	176.3	166.7	0	0	0	0	110.9	R242 P243 W246 P343 F344 L349 S350 I450	R242-V347 HydrophobicContact CB-CG1 4.36Å; R242-V347 HydrophobicContact CG-CG1 3.98Å; R242-V347 HydrophobicContact CG-CG2 4.43Å; P243-V347 HydrophobicContact CB-CG1 4.43Å; P243-V347 HydrophobicContact CG-CG1 4.2Å; W246-V347 HydrophobicContact CD2-CB 4.48Å; W246-V347 HydrophobicContact CD2-CG1 4.04Å; W246-V347 HydrophobicContact CD2-CG2 4.32Å; W246-V347 HydrophobicContact CE3-CB 3.98Å; W246-V347 HydrophobicContact CE3-CG1 3.94Å; W246-V347 HydrophobicContact CE3-CG2 3.98Å; W246-V347 HydrophobicContact CG-CG1 4.4Å; W246-V347 HydrophobicContact CH2-CG2 3.78Å; W246-V347 HydrophobicContact CZ2-CG2 4.08Å; W246-V347 HydrophobicContact CZ3-CB 4.06Å; W246-V347 HydrophobicContact CZ3-CG1 4.5Å; W246-V347 HydrophobicContact CZ3-CG2 3.71Å; P343-V347 WeakPolarHBondContact O-CB 3.36Å; P343-V347 VanDerWaalsContact O-CG2 3.28Å; P343-V347 WeakPolarHBondContact O-CG2 3.46Å; P343-V347 PolarHBondContact O-N 3.48Å; F344-V347 PolarHBondContact O-N 3.31Å; V347-L349 PolarHBondContact O-N 3.4Å; V347-S350 PolarHBondContact O-N 3.19Å; V347-S350 PolarHBondContact O-OG 2.99Å; V347-I450 HydrophobicContact CG2-CD1 4.13Å; V347-I450 HydrophobicContact CG2-CG1 4.14Å; V347-I450 HydrophobicContact CG2-CG2 3.81Å
348	F	97.9	Very high	92.6	Very high	0 Å²	0	28.4 Å²	28.4	0%	0	15%	0.146	C	C	.	.	H	α-helix	trans	-71.7	-28.5	179.4	-58	-38.6	0	0	0	113.2	P243 W246 R247 F344 F345 E351 F352 I373 D376 C380	P243-F348 HydrophobicContact CB-CD1 4.16Å; W246-F348 HydrophobicContact CB-CE1 4.37Å; R247-F348 HydrophobicContact CG-CE1 3.71Å; R247-F348 HydrophobicContact CG-CZ 3.98Å; F344-F348 HydrophobicContact CB-CD2 4.36Å; F344-F348 HydrophobicContact CB-CE2 4.01Å; F344-F348 HydrophobicContact CD1-CE2 4.27Å; F344-F348 HydrophobicContact CD1-CZ 4.37Å; F344-F348 WeakPolarHBondContact O-CD2 3.32Å; F344-F348 WeakPolarHBondContact O-CG 3.43Å; F344-F348 PolarHBondContact O-N 3.1Å; F345-F348 PolarHBondContact O-N 2.88Å; F348-E351 WeakPolarHBondContact O-CB 3.46Å; F348-F352 VanDerWaalsContact O-CD2 3.32Å; F348-F352 WeakPolarHBondContact O-CD2 3.26Å; F348-F352 WeakPolarHBondContact O-CE2 3.48Å; F348-I373 HydrophobicContact CB-CG2 4.14Å; F348-D376 HydrophobicContact CD2-CB 3.67Å; F348-D376 HydrophobicContact CE2-CB 3.84Å; F348-D376 HydrophobicContact CG-CB 4.19Å; F348-D376 HydrophobicContact CZ-CB 4.49Å; F348-C380 HydrophobicContact CE2-CB 4.07Å; F348-C380 HydrophobicContact CZ-CB 4.08Å
349	L	96.4	Very high	92.2	Very high	0 Å²	0	32.9 Å²	32.9	0%	0	17%	0.17	C	C	.	.	H	α-helix	trans	-66.7	-38.4	168.7	-179.7	59.3	0	0	0	111.9	L307 F345 V346 V347 E351 F352 V353 V357 F360 V362 L365 I373	L307-L349 HydrophobicContact CD1-CD2 3.67Å; L307-L349 HydrophobicContact CD2-CD2 3.99Å; L307-L349 HydrophobicContact CG-CD2 4.48Å; F345-L349 HydrophobicContact CE1-CD2 4.05Å; F345-L349 WeakPolarHBondContact O-CB 3.01Å; F345-L349 PolarHBondContact O-N 3.47Å; V346-L349 PolarHBondContact O-N 3.09Å; V347-L349 PolarHBondContact O-N 3.4Å; L349-E351 PolarHBondContact O-N 3.22Å; L349-E351 VanDerWaalsContact O-N 3.11Å; L349-F352 PolarHBondContact O-N 2.94Å; L349-V353 HydrophobicContact CD1-CG2 3.81Å; L349-V353 HydrophobicContact CG-CG2 4.03Å; L349-V353 PolarHBondContact O-N 3.06Å; L349-V357 HydrophobicContact CB-CG1 4.46Å; L349-V357 HydrophobicContact CD2-CG1 3.78Å; L349-V357 HydrophobicContact CG-CG1 4.04Å; L349-F360 HydrophobicContact CD1-CD1 4.19Å; L349-F360 HydrophobicContact CD1-CE1 4.2Å; L349-V362 HydrophobicContact CD1-CG2 4.24Å; L349-V362 HydrophobicContact CD2-CG2 3.83Å; L349-L365 HydrophobicContact CD1-CD1 3.55Å; L349-I373 HydrophobicContact CB-CD1 4.49Å; L349-I373 HydrophobicContact CD1-CD1 3.96Å
350	S	94.2	Very high	92.1	Very high	13 Å²	13	35.4 Å²	35.4	9%	0.091	18%	0.181	C	C	.	.	T	Hydrogen-bonded Turn	trans	-65.7	-12.1	-180	77.6	0	0	0	0	114.9	R239 V346 V347 F352	R239-S350 PolarHBondContact NH1-O 2.89Å; V346-S350 WeakPolarHBondContact O-CB 3.37Å; V346-S350 PolarHBondContact O-N 3.33Å; V347-S350 PolarHBondContact O-N 3.19Å; V347-S350 PolarHBondContact O-OG 2.99Å; S350-F352 VanDerWaalsContact C-N 3.27Å
351	E	93.5	Very high	91.9	Very high	80 Å²	80	39.4 Å²	39.4	37%	0.374	20%	0.202	S	C	.	.	T	Hydrogen-bonded Turn	trans	-69.7	-23.4	170.1	-163.7	168.7	-140.8	0	0	112.5	P243 R247 F348 L349	P243-E351 HydrophobicContact CB-CB 4.01Å; P243-E351 HydrophobicContact CB-CG 4.05Å; P243-E351 HydrophobicContact CG-CB 3.77Å; P243-E351 HydrophobicContact CG-CG 4.1Å; R247-E351 IonicContact CZ-OE1 3.72Å; R247-E351 IonicContact CZ-OE2 2.72Å; R247-E351 VanDerWaalsContact CZ-OE2 3.23Å; R247-E351 VanDerWaalsContact NH1-CD 3.26Å; R247-E351 IonicContact NH1-OE1 2.76Å; R247-E351 PolarHBondContact NH1-OE1 3.1Å; R247-E351 IonicContact NH1-OE2 3.26Å; R247-E351 PolarHBondContact NH1-OE2 3.43Å; R247-E351 IonicContact NH2-OE1 3.64Å; R247-E351 IonicContact NH2-OE2 2.6Å; R247-E351 PolarHBondContact NH2-OE2 2.82Å; F348-E351 WeakPolarHBondContact O-CB 3.46Å; L349-E351 PolarHBondContact O-N 3.22Å; L349-E351 VanDerWaalsContact O-N 3.11Å
352	F	92.9	Very high	91.7	Very high	87 Å²	87	39.5 Å²	39.5	38%	0.382	20%	0.203	S	C	.	.	T	Hydrogen-bonded Turn	trans	-115.1	-2.7	-177.9	-52.1	-79.8	0	0	0	113.4	F348 L349 S350 L365 T369 I373	F348-F352 VanDerWaalsContact O-CD2 3.32Å; F348-F352 WeakPolarHBondContact O-CD2 3.26Å; F348-F352 WeakPolarHBondContact O-CE2 3.48Å; L349-F352 PolarHBondContact O-N 2.94Å; S350-F352 VanDerWaalsContact C-N 3.27Å; F352-L365 HydrophobicContact CB-CD2 4.06Å; F352-T369 HydrophobicContact CB-CG2 4.38Å; F352-T369 HydrophobicContact CD1-CG2 3.62Å; F352-T369 HydrophobicContact CD2-CG2 3.74Å; F352-T369 HydrophobicContact CE1-CG2 3.75Å; F352-T369 HydrophobicContact CE2-CG2 3.88Å; F352-T369 HydrophobicContact CG-CG2 3.61Å; F352-T369 HydrophobicContact CZ-CG2 3.89Å; F352-I373 HydrophobicContact CD2-CD1 3.8Å; F352-I373 HydrophobicContact CD2-CG1 4.04Å; F352-I373 HydrophobicContact CE2-CD1 4.11Å; F352-I373 HydrophobicContact CE2-CG1 3.85Å
353	V	88.9	Confident	91.6	Very high	9 Å²	9	42.2 Å²	42.2	6%	0.055	23%	0.225	C	C	.	.			trans	-126.4	115.3	-175.9	-178.7	0	0	0	0	109.8	R239 L349 V357 F360	R239-V353 PolarHBondContact NH1-O 3.13Å; R239-V353 PolarHBondContact NH2-O 3.24Å; L349-V353 HydrophobicContact CD1-CG2 3.81Å; L349-V353 HydrophobicContact CG-CG2 4.03Å; L349-V353 PolarHBondContact O-N 3.06Å; V353-V357 HydrophobicContact CB-CG2 4.19Å; V353-V357 HydrophobicContact CG1-CG2 3.97Å; V353-F360 HydrophobicContact CB-CD2 4.45Å; V353-F360 HydrophobicContact CG1-CB 4.07Å; V353-F360 HydrophobicContact CG1-CD2 3.83Å; V353-F360 HydrophobicContact CG1-CG 3.96Å; V353-F360 HydrophobicContact CG2-CB 4.41Å; V353-F360 HydrophobicContact CG2-CD1 3.63Å; V353-F360 HydrophobicContact CG2-CD2 3.76Å; V353-F360 HydrophobicContact CG2-CE1 3.72Å; V353-F360 HydrophobicContact CG2-CE2 3.85Å; V353-F360 HydrophobicContact CG2-CG 3.65Å; V353-F360 HydrophobicContact CG2-CZ 3.84Å
354	T	75.7	Confident	91.4	Very high	126 Å²	126	45.8 Å²	45.8	77%	0.773	26%	0.255	S	S	*	.	S	Bend	trans	-71.5	-44.4	-173.1	45.9	0	0	0	0	113.5	R239	R239-T354 PolarHBondContact NH2-O 3.02Å
355	E	72.1	Confident	91.2	Very high	166 Å²	166	46.8 Å²	46.8	78%	0.776	26%	0.26	S	S	*	.	S	Bend	trans	-114.4	-101.9	-168.8	-65.7	174.2	-164.5	0	0	111.4	V357	E355-V357 PolarHBondContact O-N 3.41Å
356	D	82.3	Confident	91.2	Very high	69 Å²	69	50.7 Å²	50.7	37%	0.369	29%	0.285	S	S	.	.			trans	-83.9	105.6	-172	-174.3	-12.5	0	0	0	112.6	E358 N359 F360	D356-E358 WeakPolarHBondContact OD1-CA 3.14Å; D356-E358 WeakPolarHBondContact OD1-CB 3.42Å; D356-E358 PolarHBondContact OD1-N 2.79Å; D356-N359 PolarHBondContact OD1-N 2.94Å; D356-N359 WeakPolarHBondContact OD2-CB 3.37Å; D356-N359 PolarHBondContact OD2-ND2 3.25Å; D356-F360 VanDerWaalsContact O-CB 3.3Å; D356-F360 WeakPolarHBondContact O-CB 3.21Å
357	V	86.8	Confident	91.1	Very high	12 Å²	12	56 Å²	56	7%	0.073	31%	0.313	C	S	.	.	S	Bend	trans	-83.9	-15.1	176.3	-172.2	0	0	0	0	112.3	L307 V346 L349 V353 E355	L307-V357 HydrophobicContact CD2-CG1 4.48Å; V346-V357 HydrophobicContact CG1-CG1 4.24Å; L349-V357 HydrophobicContact CB-CG1 4.46Å; L349-V357 HydrophobicContact CD2-CG1 3.78Å; L349-V357 HydrophobicContact CG-CG1 4.04Å; V353-V357 HydrophobicContact CB-CG2 4.19Å; V353-V357 HydrophobicContact CG1-CG2 3.97Å; E355-V357 PolarHBondContact O-N 3.41Å
358	E	87.6	Confident	91.1	Very high	20 Å²	20	62.8 Å²	62.8	9%	0.093	35%	0.345	C	S	.	.	S	Bend	trans	-77.8	-35.1	-179	-61.2	-167.8	-136.7	0	0	112.5	I190 S191 I305 L307 D356	I190-E358 HydrophobicContact CB-CG 3.57Å; I190-E358 HydrophobicContact CD1-CG 3.99Å; I190-E358 HydrophobicContact CG1-CG 3.69Å; I190-E358 VanDerWaalsContact N-CD 3.33Å; I190-E358 PolarHBondContact N-OE1 3.01Å; S191-E358 VanDerWaalsContact CB-OE1 3.31Å; S191-E358 WeakPolarHBondContact CB-OE1 3.43Å; S191-E358 PolarHBondContact N-OE1 3.13Å; S191-E358 PolarHBondContact OG-OE1 3.08Å; I305-E358 HydrophobicContact CG2-CB 4.31Å; I305-E358 HydrophobicContact CG2-CG 4.4Å; L307-E358 PolarHBondContact N-O 2.85Å; D356-E358 WeakPolarHBondContact OD1-CA 3.14Å; D356-E358 WeakPolarHBondContact OD1-CB 3.42Å; D356-E358 PolarHBondContact OD1-N 2.79Å
359	N	88.8	Confident	91	Very high	100 Å²	100	63.9 Å²	63.9	54%	0.535	35%	0.352	S	S	.	.	S	Bend	trans	-108.5	-1.8	-176.5	-62.5	-68	0	0	0	114	P306 D356 D361	P306-N359 WeakPolarHBondContact CG-OD1 3.34Å; D356-N359 PolarHBondContact OD1-N 2.94Å; D356-N359 WeakPolarHBondContact OD2-CB 3.37Å; D356-N359 PolarHBondContact OD2-ND2 3.25Å; N359-D361 PolarHBondContact O-N 2.93Å
360	F	92.9	Very high	91.1	Very high	53 Å²	53	65.4 Å²	65.4	23%	0.232	36%	0.358	C	S	.	.			trans	-66.9	127.4	178.2	-179.4	-91.1	0	0	0	112.5	Q310 L349 V353 D356 V362 L365	Q310-F360 PolarHBondContact NE2-O 3.27Å; L349-F360 HydrophobicContact CD1-CD1 4.19Å; L349-F360 HydrophobicContact CD1-CE1 4.2Å; V353-F360 HydrophobicContact CB-CD2 4.45Å; V353-F360 HydrophobicContact CG1-CB 4.07Å; V353-F360 HydrophobicContact CG1-CD2 3.83Å; V353-F360 HydrophobicContact CG1-CG 3.96Å; V353-F360 HydrophobicContact CG2-CB 4.41Å; V353-F360 HydrophobicContact CG2-CD1 3.63Å; V353-F360 HydrophobicContact CG2-CD2 3.76Å; V353-F360 HydrophobicContact CG2-CE1 3.72Å; V353-F360 HydrophobicContact CG2-CE2 3.85Å; V353-F360 HydrophobicContact CG2-CG 3.65Å; V353-F360 HydrophobicContact CG2-CZ 3.84Å; D356-F360 VanDerWaalsContact O-CB 3.3Å; D356-F360 WeakPolarHBondContact O-CB 3.21Å; F360-V362 HydrophobicContact CD1-CG2 4.43Å; F360-V362 PolarHBondContact O-N 3.31Å; F360-L365 HydrophobicContact CE1-CD1 3.78Å; F360-L365 HydrophobicContact CE1-CD2 4.26Å; F360-L365 HydrophobicContact CE1-CG 3.66Å; F360-L365 HydrophobicContact CZ-CD1 4.29Å; F360-L365 HydrophobicContact CZ-CD2 3.91Å; F360-L365 HydrophobicContact CZ-CG 3.75Å
361	D	94.1	Very high	91.2	Very high	84 Å²	84	69.4 Å²	69.4	45%	0.449	37%	0.372	S	S	.	.			trans	-75.1	108.9	174.4	179	13.5	0	0	0	111.4	N359 A363 A364	N359-D361 PolarHBondContact O-N 2.93Å; D361-A363 PolarHBondContact O-N 2.83Å; D361-A363 VanDerWaalsContact OD1-CB 3.27Å; D361-A363 WeakPolarHBondContact OD1-CB 3.48Å; D361-A363 PolarHBondContact OD1-N 3.16Å; D361-A364 HydrophobicContact CB-CB 4.46Å; D361-A364 WeakPolarHBondContact O-CB 3.23Å; D361-A364 PolarHBondContact O-N 3.19Å; D361-A364 VanDerWaalsContact O-N 3.1Å
362	V	94.9	Very high	91.5	Very high	2 Å²	2	66.9 Å²	66.9	1%	0.012	36%	0.361	C	S	.	.	G	3₁₀ helix	trans	-64.3	-25.9	179.6	175.4	0	0	0	0	112	L307 V313 F345 L349 F360 A364 L365 Q370	L307-V362 HydrophobicContact CD1-CG2 3.53Å; V313-V362 HydrophobicContact CG2-CB 3.92Å; V313-V362 HydrophobicContact CG2-CG1 4.35Å; V313-V362 HydrophobicContact CG2-CG2 3.65Å; F345-V362 HydrophobicContact CE1-CG2 4.43Å; F345-V362 HydrophobicContact CZ-CG1 4.33Å; F345-V362 HydrophobicContact CZ-CG2 4.21Å; L349-V362 HydrophobicContact CD1-CG2 4.24Å; L349-V362 HydrophobicContact CD2-CG2 3.83Å; F360-V362 HydrophobicContact CD1-CG2 4.43Å; F360-V362 PolarHBondContact O-N 3.31Å; V362-A364 PolarHBondContact O-N 3.48Å; V362-L365 PolarHBondContact O-N 3.1Å; V362-Q370 HydrophobicContact CG1-CG 4.21Å; V362-Q370 PolarHBondContact O-NE2 3.33Å
363	A	94.7	Very high	91.7	Very high	57 Å²	57	62.8 Å²	62.8	47%	0.471	34%	0.343	S	S	.	.	G	3₁₀ helix	trans	-67.9	-18.4	176.9	0	0	0	0	0	113.1	D361 L365	D361-A363 PolarHBondContact O-N 2.83Å; D361-A363 VanDerWaalsContact OD1-CB 3.27Å; D361-A363 WeakPolarHBondContact OD1-CB 3.48Å; D361-A363 PolarHBondContact OD1-N 3.16Å; A363-L365 VanDerWaalsContact C-N 3.32Å
364	A	93.9	Very high	92.2	Very high	74 Å²	74	62.5 Å²	62.5	61%	0.612	34%	0.341	S	S	*	.	G	3₁₀ helix	trans	-75.8	-15.8	175.8	0	0	0	0	0	113.7	D361 V362	D361-A364 HydrophobicContact CB-CB 4.46Å; D361-A364 WeakPolarHBondContact O-CB 3.23Å; D361-A364 PolarHBondContact O-N 3.19Å; D361-A364 VanDerWaalsContact O-N 3.1Å; V362-A364 PolarHBondContact O-N 3.48Å
365	L	95.3	Very high	93.3	Very high	22 Å²	22	56.5 Å²	56.5	12%	0.115	30%	0.304	C	S	.	.	S	Bend	trans	-74.9	150.7	174.6	-73.3	170.7	0	0	0	111.6	L349 F352 F360 V362 A363 L367 T369 Q370 I373	L349-L365 HydrophobicContact CD1-CD1 3.55Å; F352-L365 HydrophobicContact CB-CD2 4.06Å; F360-L365 HydrophobicContact CE1-CD1 3.78Å; F360-L365 HydrophobicContact CE1-CD2 4.26Å; F360-L365 HydrophobicContact CE1-CG 3.66Å; F360-L365 HydrophobicContact CZ-CD1 4.29Å; F360-L365 HydrophobicContact CZ-CD2 3.91Å; F360-L365 HydrophobicContact CZ-CG 3.75Å; V362-L365 PolarHBondContact O-N 3.1Å; A363-L365 VanDerWaalsContact C-N 3.32Å; L365-L367 PolarHBondContact O-N 2.88Å; L365-T369 HydrophobicContact CD1-CG2 4.29Å; L365-T369 HydrophobicContact CD2-CG2 4.29Å; L365-Q370 HydrophobicContact CB-CG 3.89Å; L365-Q370 PolarHBondContact O-NE2 3.43Å; L365-I373 HydrophobicContact CD1-CD1 3.92Å
366	P	97.1	Very high	94.6	Very high	84 Å²	84	48.6 Å²	48.6	55%	0.545	27%	0.267	S	S	.	.			trans	-52.5	139	168.3	-24.5	33.9	0	0	0	111.4	E368 T369 Q370	P366-E368 PolarHBondContact O-N 3.45Å; P366-E368 VanDerWaalsContact O-N 3.13Å; P366-T369 WeakPolarHBondContact O-CA 3.42Å; P366-T369 WeakPolarHBondContact O-CB 3.16Å; P366-T369 PolarHBondContact O-N 2.88Å; P366-Q370 PolarHBondContact O-N 3.04Å
367	L	96.1	Very high	95.3	Very high	117 Å²	117	45.3 Å²	45.3	61%	0.613	25%	0.25	S	C	*	.	H	α-helix	trans	-57.2	-32.9	-177	-178.9	62.3	0	0	0	112.7	L365 R371	L365-L367 PolarHBondContact O-N 2.88Å; L367-R371 WeakPolarHBondContact O-CB 3.23Å; L367-R371 VanDerWaalsContact O-CG 3.26Å; L367-R371 WeakPolarHBondContact O-CG 3.34Å; L367-R371 PolarHBondContact O-N 3.28Å
368	E	96.2	Very high	95.9	Very high	144 Å²	144	44.9 Å²	44.9	67%	0.673	25%	0.247	S	C	*	.	H	α-helix	trans	-65.1	-41.1	173.1	-170	177.6	165.2	0	0	112	P366 R371 N372	P366-E368 PolarHBondContact O-N 3.45Å; P366-E368 VanDerWaalsContact O-N 3.13Å; E368-R371 PolarHBondContact O-N 3.37Å; E368-N372 VanDerWaalsContact O-CB 3.3Å; E368-N372 WeakPolarHBondContact O-CB 3.4Å; E368-N372 PolarHBondContact O-N 3.49Å; E368-N372 PolarHBondContact O-ND2 3.48Å; E368-N372 VanDerWaalsContact O-ND2 3.16Å
369	T	96.9	Very high	96.4	Very high	23 Å²	23	45.3 Å²	45.3	14%	0.141	25%	0.248	C	C	.	.	H	α-helix	trans	-63.6	-45.1	174.9	-52.1	0	0	0	0	111.5	F352 L365 P366 R371 N372 I373	F352-T369 HydrophobicContact CB-CG2 4.38Å; F352-T369 HydrophobicContact CD1-CG2 3.62Å; F352-T369 HydrophobicContact CD2-CG2 3.74Å; F352-T369 HydrophobicContact CE1-CG2 3.75Å; F352-T369 HydrophobicContact CE2-CG2 3.88Å; F352-T369 HydrophobicContact CG-CG2 3.61Å; F352-T369 HydrophobicContact CZ-CG2 3.89Å; L365-T369 HydrophobicContact CD1-CG2 4.29Å; L365-T369 HydrophobicContact CD2-CG2 4.29Å; P366-T369 WeakPolarHBondContact O-CA 3.42Å; P366-T369 WeakPolarHBondContact O-CB 3.16Å; P366-T369 PolarHBondContact O-N 2.88Å; T369-R371 VanDerWaalsContact C-N 3.34Å; T369-R371 PolarHBondContact O-N 2.99Å; T369-N372 WeakPolarHBondContact O-CB 3.27Å; T369-N372 PolarHBondContact O-N 3.34Å; T369-I373 HydrophobicContact CG2-CD1 4.14Å; T369-I373 WeakPolarHBondContact O-CG1 3.18Å; T369-I373 PolarHBondContact O-N 3.01Å
370	Q	97.6	Very high	96.9	Very high	31 Å²	31	40.6 Å²	40.6	15%	0.145	22%	0.222	C	C	.	.	H	α-helix	trans	-57.6	-47	174.5	-61	180	35.3	0	0	111.2	V362 L365 P366 N372 I373 E374	V362-Q370 HydrophobicContact CG1-CG 4.21Å; V362-Q370 PolarHBondContact O-NE2 3.33Å; L365-Q370 HydrophobicContact CB-CG 3.89Å; L365-Q370 PolarHBondContact O-NE2 3.43Å; P366-Q370 PolarHBondContact O-N 3.04Å; Q370-N372 PolarHBondContact O-N 2.87Å; Q370-I373 PolarHBondContact O-N 3.45Å; Q370-E374 PolarHBondContact O-N 2.96Å
371	R	97.7	Very high	97.2	Very high	97 Å²	97	38 Å²	38	37%	0.366	21%	0.211	S	C	.	.	H	α-helix	trans	-61.8	-39.1	176.3	-79.2	-179.6	74.5	159.2	2.1	112.9	F272 L367 E368 T369 E374 A375	F272-R371 HydrophobicContact CE1-CB 4.16Å; F272-R371 HydrophobicContact CE1-CG 3.85Å; F272-R371 HydrophobicContact CE2-CB 3.74Å; F272-R371 HydrophobicContact CE2-CG 4.26Å; F272-R371 HydrophobicContact CZ-CB 3.34Å; F272-R371 HydrophobicContact CZ-CG 3.55Å; F272-R371 VanDerWaalsContact CZ-O 3.31Å; F272-R371 WeakPolarHBondContact CZ-O 3.16Å; L367-R371 WeakPolarHBondContact O-CB 3.23Å; L367-R371 VanDerWaalsContact O-CG 3.26Å; L367-R371 WeakPolarHBondContact O-CG 3.34Å; L367-R371 PolarHBondContact O-N 3.28Å; E368-R371 PolarHBondContact O-N 3.37Å; T369-R371 VanDerWaalsContact C-N 3.34Å; T369-R371 PolarHBondContact O-N 2.99Å; R371-E374 PolarHBondContact O-N 3.02Å; R371-A375 WeakPolarHBondContact O-CB 3.33Å; R371-A375 PolarHBondContact O-N 2.9Å
372	N	98.1	Very high	97.4	Very high	28 Å²	28	34.5 Å²	34.5	15%	0.15	19%	0.193	C	C	.	.	H	α-helix	trans	-64.9	-44.1	176.9	-74	-25.6	0	0	0	111.6	R268 E368 T369 Q370 D376	R268-N372 VanDerWaalsContact CD-OD1 3.29Å; R268-N372 WeakPolarHBondContact CD-OD1 3.47Å; R268-N372 PolarHBondContact NH1-ND2 2.84Å; R268-N372 PolarHBondContact NH1-OD1 3.41Å; R268-N372 VanDerWaalsContact NH1-OD1 3.17Å; E368-N372 VanDerWaalsContact O-CB 3.3Å; E368-N372 WeakPolarHBondContact O-CB 3.4Å; E368-N372 PolarHBondContact O-N 3.49Å; E368-N372 PolarHBondContact O-ND2 3.48Å; E368-N372 VanDerWaalsContact O-ND2 3.16Å; T369-N372 WeakPolarHBondContact O-CB 3.27Å; T369-N372 PolarHBondContact O-N 3.34Å; Q370-N372 PolarHBondContact O-N 2.87Å; N372-D376 WeakPolarHBondContact O-CB 3.46Å; N372-D376 PolarHBondContact O-N 3.17Å
373	I	98.5	Very high	97.5	Very high	1 Å²	1	39 Å²	39	1%	0.005	21%	0.212	C	C	.	.	H	α-helix	trans	-62.4	-45.9	175.5	-65.7	161.6	0	0	0	110.9	F345 F348 L349 F352 L365 T369 Q370 S377	F345-I373 HydrophobicContact CD2-CG2 3.61Å; F345-I373 HydrophobicContact CE2-CG2 3.6Å; F345-I373 HydrophobicContact CG-CG2 4.46Å; F345-I373 HydrophobicContact CZ-CG2 4.45Å; F348-I373 HydrophobicContact CB-CG2 4.14Å; L349-I373 HydrophobicContact CB-CD1 4.49Å; L349-I373 HydrophobicContact CD1-CD1 3.96Å; F352-I373 HydrophobicContact CD2-CD1 3.8Å; F352-I373 HydrophobicContact CD2-CG1 4.04Å; F352-I373 HydrophobicContact CE2-CD1 4.11Å; F352-I373 HydrophobicContact CE2-CG1 3.85Å; L365-I373 HydrophobicContact CD1-CD1 3.92Å; T369-I373 HydrophobicContact CG2-CD1 4.14Å; T369-I373 WeakPolarHBondContact O-CG1 3.18Å; T369-I373 PolarHBondContact O-N 3.01Å; Q370-I373 PolarHBondContact O-N 3.45Å; I373-S377 VanDerWaalsContact O-CB 3.31Å; I373-S377 WeakPolarHBondContact O-CB 3.44Å; I373-S377 PolarHBondContact O-N 2.92Å; I373-S377 PolarHBondContact O-OG 3.09Å
374	E	98.7	Very high	97.6	Very high	3 Å²	3	36.8 Å²	36.8	1%	0.014	19%	0.192	C	C	.	.	H	α-helix	trans	-59	-50.2	179.1	174.9	177	165.8	0	0	112	Y271 I275 V316 R319 I320 Q370 R371 S377 F378	Y271-E374 HydrophobicContact CE1-CG 3.67Å; Y271-E374 WeakPolarHBondContact CE1-OE1 3.33Å; Y271-E374 PolarHBondContact OH-OE1 3.16Å; I275-E374 WeakPolarHBondContact CD1-OE1 3.35Å; V316-E374 HydrophobicContact CG1-CB 3.98Å; V316-E374 HydrophobicContact CG1-CG 3.91Å; V316-E374 HydrophobicContact CG2-CB 4.46Å; R319-E374 VanDerWaalsContact CB-OE1 3.29Å; R319-E374 WeakPolarHBondContact CB-OE1 3.32Å; R319-E374 WeakPolarHBondContact CD-OE1 3.26Å; R319-E374 IonicContact CZ-OE1 2.65Å; R319-E374 IonicContact CZ-OE2 3.63Å; R319-E374 IonicContact NE-OE1 2.74Å; R319-E374 PolarHBondContact NE-OE1 2.94Å; R319-E374 IonicContact NE-OE2 3.73Å; R319-E374 PolarHBondContact NE-OE2 3.43Å; R319-E374 VanDerWaalsContact NE-OE2 3.15Å; R319-E374 IonicContact NH2-OE1 2.94Å; R319-E374 IonicContact NH2-OE2 2.68Å; R319-E374 PolarHBondContact NH2-OE2 2.9Å; I320-E374 HydrophobicContact CD1-CG 4.1Å; I320-E374 HydrophobicContact CG1-CG 3.93Å; Q370-E374 PolarHBondContact O-N 2.96Å; R371-E374 PolarHBondContact O-N 3.02Å; E374-S377 WeakPolarHBondContact O-CB 3.33Å; E374-S377 PolarHBondContact O-N 3.49Å; E374-F378 PolarHBondContact O-N 3.26Å
375	A	98.8	Very high	97.7	Very high	0 Å²	0	33.3 Å²	33.3	0%	0	16%	0.163	C	C	.	.	H	α-helix	trans	-66.9	-41.3	-178.4	0	0	0	0	0	112.8	R268 Y271 F272 R371 S377 F378 W379	R268-A375 HydrophobicContact CB-CB 4.15Å; R268-A375 HydrophobicContact CG-CB 3.83Å; Y271-A375 HydrophobicContact CD1-CB 3.62Å; Y271-A375 HydrophobicContact CE1-CB 4.36Å; Y271-A375 HydrophobicContact CG-CB 4.09Å; F272-A375 HydrophobicContact CE2-CB 4.09Å; F272-A375 HydrophobicContact CZ-CB 4.4Å; R371-A375 WeakPolarHBondContact O-CB 3.33Å; R371-A375 PolarHBondContact O-N 2.9Å; A375-S377 VanDerWaalsContact C-N 3.33Å; A375-F378 PolarHBondContact O-N 3.44Å; A375-W379 PolarHBondContact O-N 3.33Å; A375-W379 VanDerWaalsContact O-N 3.13Å
376	D	98.8	Very high	97.7	Very high	0 Å²	0	35.3 Å²	35.3	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-63.1	-42	175.5	-69.4	6.4	0	0	0	110.9	R247 Y252 R268 F348 N372 F378 W379 C380	R247-D376 IonicContact CZ-OD2 2.77Å; R247-D376 IonicContact NE-OD2 2.7Å; R247-D376 PolarHBondContact NE-OD2 3.39Å; R247-D376 IonicContact NH2-OD2 2.81Å; R247-D376 PolarHBondContact NH2-OD2 3.14Å; Y252-D376 HydrophobicContact CE1-CB 4.25Å; Y252-D376 PolarHBondContact OH-OD1 2.94Å; R268-D376 IonicContact CZ-OD1 2.92Å; R268-D376 IonicContact CZ-OD2 2.68Å; R268-D376 IonicContact NE-OD1 2.8Å; R268-D376 PolarHBondContact NE-OD1 3.32Å; R268-D376 IonicContact NE-OD2 2.71Å; R268-D376 VanDerWaalsContact NH2-CG 3.3Å; R268-D376 IonicContact NH2-OD1 3.72Å; R268-D376 PolarHBondContact NH2-OD1 3.33Å; R268-D376 VanDerWaalsContact NH2-OD1 3.13Å; R268-D376 IonicContact NH2-OD2 3.96Å; R268-D376 PolarHBondContact NH2-OD2 2.99Å; F348-D376 HydrophobicContact CD2-CB 3.67Å; F348-D376 HydrophobicContact CE2-CB 3.84Å; F348-D376 HydrophobicContact CG-CB 4.19Å; F348-D376 HydrophobicContact CZ-CB 4.49Å; N372-D376 WeakPolarHBondContact O-CB 3.46Å; N372-D376 PolarHBondContact O-N 3.17Å; D376-F378 PolarHBondContact O-N 3.35Å; D376-W379 PolarHBondContact O-N 3.48Å; D376-C380 PolarHBondContact O-N 3.27Å
377	S	98.8	Very high	97.5	Very high	0 Å²	0	33.2 Å²	33.2	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-60.4	-45.4	176.4	-58.2	0	0	0	0	111.6	F345 I373 E374 A375 W379 M381	F345-S377 WeakPolarHBondContact CA-OG 3.3Å; I373-S377 VanDerWaalsContact O-CB 3.31Å; I373-S377 WeakPolarHBondContact O-CB 3.44Å; I373-S377 PolarHBondContact O-N 2.92Å; I373-S377 PolarHBondContact O-OG 3.09Å; E374-S377 WeakPolarHBondContact O-CB 3.33Å; E374-S377 PolarHBondContact O-N 3.49Å; A375-S377 VanDerWaalsContact C-N 3.33Å; S377-W379 PolarHBondContact O-N 3.05Å; S377-M381 WeakPolarHBondContact O-CB 3.49Å; S377-M381 PolarHBondContact O-N 3.2Å
378	F	98.8	Very high	97.5	Very high	2 Å²	2	27.7 Å²	27.7	1%	0.009	14%	0.139	C	C	.	.	H	α-helix	trans	-58	-46.7	175.4	169.5	-94.3	0	0	0	112.5	Y271 F274 I320 I323 W324 E374 A375 D376 S382	Y271-F378 HydrophobicContact CD2-CB 3.82Å; Y271-F378 AromaticContact CD2-CD1 3.34Å; Y271-F378 HydrophobicContact CD2-CD1 3.34Å; Y271-F378 AromaticContact CD2-CD2 3.91Å; Y271-F378 HydrophobicContact CD2-CD2 3.91Å; Y271-F378 AromaticContact CD2-CE1 3.83Å; Y271-F378 HydrophobicContact CD2-CE1 3.83Å; Y271-F378 HydrophobicContact CD2-CE2 4.33Å; Y271-F378 AromaticContact CD2-CG 3.39Å; Y271-F378 HydrophobicContact CD2-CG 3.39Å; Y271-F378 HydrophobicContact CD2-CZ 4.3Å; Y271-F378 HydrophobicContact CE2-CB 3.62Å; Y271-F378 AromaticContact CE2-CD1 3.87Å; Y271-F378 HydrophobicContact CE2-CD1 3.87Å; Y271-F378 AromaticContact CE2-CD2 3.56Å; Y271-F378 HydrophobicContact CE2-CD2 3.56Å; Y271-F378 HydrophobicContact CE2-CE1 4.45Å; Y271-F378 HydrophobicContact CE2-CE2 4.19Å; Y271-F378 AromaticContact CE2-CG 3.38Å; Y271-F378 HydrophobicContact CE2-CG 3.38Å; Y271-F378 HydrophobicContact CG-CD1 4.2Å; Y271-F378 HydrophobicContact CG-CG 4.42Å; F274-F378 HydrophobicContact CD2-CE1 4.41Å; F274-F378 HydrophobicContact CD2-CZ 4.36Å; F274-F378 HydrophobicContact CE2-CE1 4.29Å; F274-F378 HydrophobicContact CE2-CZ 4.45Å; I320-F378 HydrophobicContact CG1-CB 4.32Å; I320-F378 HydrophobicContact CG2-CB 4.31Å; I320-F378 HydrophobicContact CG2-CD2 4.36Å; I323-F378 HydrophobicContact CB-CE2 4.36Å; I323-F378 HydrophobicContact CG2-CD2 4.5Å; I323-F378 HydrophobicContact CG2-CE2 3.81Å; I323-F378 HydrophobicContact CG2-CZ 4.1Å; W324-F378 HydrophobicContact CB-CE2 4.07Å; E374-F378 PolarHBondContact O-N 3.26Å; A375-F378 PolarHBondContact O-N 3.44Å; D376-F378 PolarHBondContact O-N 3.35Å; F378-S382 VanDerWaalsContact O-CB 3.32Å; F378-S382 WeakPolarHBondContact O-CB 3.44Å; F378-S382 PolarHBondContact O-N 3.48Å; F378-S382 PolarHBondContact O-OG 2.8Å
379	W	98.8	Very high	97.5	Very high	30 Å²	30	25.2 Å²	25.2	11%	0.114	13%	0.127	C	C	.	.	H	α-helix	trans	-72	-42	-176.1	-74.2	115.7	0	0	0	113	Y252 K267 E270 F274 A375 D376 S377 S382 K383	Y252-W379 HydrophobicContact CD2-CB 3.4Å; Y252-W379 AromaticContact CD2-CG 3.88Å; Y252-W379 HydrophobicContact CD2-CG 3.88Å; Y252-W379 HydrophobicContact CE1-CB 4.49Å; Y252-W379 HydrophobicContact CE2-CB 3.34Å; Y252-W379 AromaticContact CE2-CD1 3.44Å; Y252-W379 VanDerWaalsContact CE2-CD1 3.44Å; Y252-W379 HydrophobicContact CE2-CD2 4.32Å; Y252-W379 AromaticContact CE2-CG 3.4Å; Y252-W379 HydrophobicContact CE2-CG 3.4Å; Y252-W379 VanDerWaalsContact CE2-CG 3.4Å; Y252-W379 HydrophobicContact CG-CB 4.02Å; Y252-W379 AromaticContact CZ-CD1 3.8Å; K267-W379 HydrophobicContact CD-CD2 3.74Å; K267-W379 HydrophobicContact CD-CE3 4.18Å; K267-W379 HydrophobicContact CD-CG 4.28Å; K267-W379 HydrophobicContact CD-CH2 4.08Å; K267-W379 HydrophobicContact CD-CZ2 3.58Å; K267-W379 HydrophobicContact CD-CZ3 4.34Å; K267-W379 PolarHBondContact O-NE1 3.01Å; E270-W379 HydrophobicContact CB-CZ2 4.27Å; E270-W379 HydrophobicContact CG-CH2 4.41Å; E270-W379 HydrophobicContact CG-CZ2 3.99Å; E270-W379 WeakPolarHBondContact OE1-CH2 3.27Å; E270-W379 WeakPolarHBondContact OE1-CZ2 3.48Å; F274-W379 AromaticContact CE2-CH2 3.81Å; F274-W379 HydrophobicContact CE2-CH2 3.81Å; F274-W379 AromaticContact CE2-CZ2 3.91Å; F274-W379 HydrophobicContact CE2-CZ2 3.91Å; F274-W379 HydrophobicContact CZ-CH2 4.21Å; F274-W379 HydrophobicContact CZ-CZ2 4.42Å; A375-W379 PolarHBondContact O-N 3.33Å; A375-W379 VanDerWaalsContact O-N 3.13Å; D376-W379 PolarHBondContact O-N 3.48Å; S377-W379 PolarHBondContact O-N 3.05Å; W379-S382 PolarHBondContact O-N 3.24Å; W379-K383 PolarHBondContact O-N 3.02Å
380	C	98.5	Very high	97.5	Very high	0 Å²	0	27 Å²	27	0%	0	14%	0.136	C	C	.	.	H	α-helix	trans	-70.6	-37.3	176.8	-70	0	0	0	0	112.4	S250 F344 F348 D376 S382 K383 L384	S250-C380 PolarHBondContact OG-SG 2.87Å; F344-C380 HydrophobicContact CD1-CB 3.5Å; F344-C380 VanDerWaalsContact CD1-CB 3.5Å; F344-C380 HydrophobicContact CE1-CB 3.61Å; F344-C380 HydrophobicContact CG-CB 4.13Å; F344-C380 HydrophobicContact CZ-CB 4.28Å; F348-C380 HydrophobicContact CE2-CB 4.07Å; F348-C380 HydrophobicContact CZ-CB 4.08Å; D376-C380 PolarHBondContact O-N 3.27Å; C380-S382 PolarHBondContact O-N 3.27Å; C380-K383 PolarHBondContact O-N 3.31Å; C380-L384 PolarHBondContact O-N 3.31Å
381	M	98.4	Very high	97.5	Very high	0 Å²	0	25.6 Å²	25.6	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-61.2	-43.3	169.8	-175.4	-158.4	66.6	0	0	111.5	I320 L321 W324 I337 V341 F344 S377 K383 L384 L385	I320-M381 HydrophobicContact CG2-CE 3.81Å; I320-M381 HydrophobicContact CG2-SD 4.11Å; L321-M381 HydrophobicContact CD2-SD 4.42Å; W324-M381 HydrophobicContact CB-CE 3.77Å; W324-M381 HydrophobicContact CD2-CE 4.41Å; W324-M381 HydrophobicContact CG-CE 3.63Å; I337-M381 HydrophobicContact CG2-SD 4.37Å; V341-M381 HydrophobicContact CB-SD 4.49Å; V341-M381 HydrophobicContact CG2-SD 3.52Å; V341-M381 VanDerWaalsContact CG2-SD 3.52Å; F344-M381 HydrophobicContact CD2-CB 3.93Å; F344-M381 HydrophobicContact CE2-CB 4.12Å; S377-M381 WeakPolarHBondContact O-CB 3.49Å; S377-M381 PolarHBondContact O-N 3.2Å; M381-K383 VanDerWaalsContact C-N 3.28Å; M381-K383 PolarHBondContact O-N 3.4Å; M381-L384 WeakPolarHBondContact O-CB 3.2Å; M381-L384 PolarHBondContact O-N 3.11Å; M381-L385 HydrophobicContact CE-CD1 3.95Å; M381-L385 HydrophobicContact CG-CD1 3.8Å; M381-L385 HydrophobicContact CG-CG 4.46Å; M381-L385 WeakPolarHBondContact O-CG 3.28Å; M381-L385 PolarHBondContact O-N 3.42Å; M381-L385 HydrophobicContact SD-CD1 4.07Å
382	S	98.3	Very high	97.5	Very high	9 Å²	9	21.1 Å²	21.1	6%	0.063	11%	0.113	C	C	.	.	H	α-helix	trans	-59.7	-39.9	175.7	-60.4	0	0	0	0	111.6	F378 W379 C380 L385 D386	F378-S382 VanDerWaalsContact O-CB 3.32Å; F378-S382 WeakPolarHBondContact O-CB 3.44Å; F378-S382 PolarHBondContact O-N 3.48Å; F378-S382 PolarHBondContact O-OG 2.8Å; W379-S382 PolarHBondContact O-N 3.24Å; C380-S382 PolarHBondContact O-N 3.27Å; S382-L385 PolarHBondContact O-N 3.14Å; S382-D386 PolarHBondContact O-N 2.86Å
383	K	96.8	Very high	97.5	Very high	97 Å²	97	21.7 Å²	21.7	42%	0.422	12%	0.117	S	C	.	.	H	α-helix	trans	-68.3	-33.5	176.4	-78.6	-74.1	148.1	-136.3	0	113.9	S250 W379 C380 M381 D386	S250-K383 WeakPolarHBondContact O-CB 3.42Å; S250-K383 VanDerWaalsContact O-CD 3.31Å; S250-K383 WeakPolarHBondContact O-CD 3.19Å; S250-K383 VanDerWaalsContact O-CG 3.31Å; S250-K383 WeakPolarHBondContact O-CG 3.4Å; W379-K383 PolarHBondContact O-N 3.02Å; C380-K383 PolarHBondContact O-N 3.31Å; M381-K383 VanDerWaalsContact C-N 3.28Å; M381-K383 PolarHBondContact O-N 3.4Å; K383-D386 IonicContact NZ-OD2 3.23Å; K383-D386 PolarHBondContact NZ-OD2 2.97Å
384	L	96.9	Very high	97.4	Very high	10 Å²	10	29.3 Å²	29.3	5%	0.052	15%	0.151	C	C	.	.	H	α-helix	trans	-64.6	-47.5	170	-174.4	75.6	0	0	0	110.8	F344 C380 M381 D386 G387 L439 W453 F463	F344-L384 HydrophobicContact CE2-CB 4.12Å; F344-L384 HydrophobicContact CE2-CD2 3.91Å; F344-L384 HydrophobicContact CZ-CB 4.01Å; F344-L384 HydrophobicContact CZ-CD2 4.21Å; C380-L384 PolarHBondContact O-N 3.31Å; M381-L384 WeakPolarHBondContact O-CB 3.2Å; M381-L384 PolarHBondContact O-N 3.11Å; L384-D386 VanDerWaalsContact C-N 3.33Å; L384-D386 PolarHBondContact O-N 3.3Å; L384-G387 PolarHBondContact O-N 3.13Å; L384-G387 VanDerWaalsContact O-N 3.16Å; L384-L439 HydrophobicContact CD1-CD1 4.42Å; L384-L439 HydrophobicContact CD2-CD1 4Å; L384-L439 HydrophobicContact CG-CD1 4.42Å; L384-W453 HydrophobicContact CD2-CE3 4.38Å; L384-W453 HydrophobicContact CD2-CH2 3.42Å; L384-W453 VanDerWaalsContact CD2-CH2 3.42Å; L384-W453 HydrophobicContact CD2-CZ2 4.02Å; L384-W453 HydrophobicContact CD2-CZ3 3.65Å; L384-F463 HydrophobicContact CD1-CD1 4.26Å; L384-F463 HydrophobicContact CD1-CE1 3.63Å; L384-F463 HydrophobicContact CD1-CE2 4Å; L384-F463 HydrophobicContact CD1-CZ 3.47Å; L384-F463 VanDerWaalsContact CD1-CZ 3.47Å; L384-F463 HydrophobicContact CG-CE1 4.38Å; L384-F463 HydrophobicContact CG-CZ 3.96Å
385	L	97.1	Very high	97.2	Very high	1 Å²	1	32 Å²	32	1%	0.005	17%	0.174	C	C	.	.	H	α-helix	trans	-67.9	-29.1	-177	-70.8	167	0	0	0	113.1	W324 I337 L340 M381 S382 G387 I388 Q389 Y392	W324-L385 HydrophobicContact CD2-CD1 3.98Å; W324-L385 VanDerWaalsContact CE2-CD1 3.43Å; W324-L385 HydrophobicContact CG-CD1 4.46Å; W324-L385 HydrophobicContact CH2-CD1 4.28Å; W324-L385 HydrophobicContact CZ2-CB 3.9Å; W324-L385 HydrophobicContact CZ2-CD1 3.63Å; W324-L385 HydrophobicContact CZ2-CG 4.24Å; I337-L385 HydrophobicContact CG2-CD1 3.91Å; L340-L385 HydrophobicContact CD1-CD2 3.77Å; M381-L385 HydrophobicContact CE-CD1 3.95Å; M381-L385 HydrophobicContact CG-CD1 3.8Å; M381-L385 HydrophobicContact CG-CG 4.46Å; M381-L385 WeakPolarHBondContact O-CG 3.28Å; M381-L385 PolarHBondContact O-N 3.42Å; M381-L385 HydrophobicContact SD-CD1 4.07Å; S382-L385 PolarHBondContact O-N 3.14Å; L385-G387 PolarHBondContact O-N 3.41Å; L385-I388 HydrophobicContact CD2-CD1 4.35Å; L385-I388 HydrophobicContact CD2-CG1 4.4Å; L385-I388 CarbonylContact O-C 3.39Å; L385-I388 PolarHBondContact O-N 2.95Å; L385-Q389 VanDerWaalsContact O-CG 3.27Å; L385-Q389 WeakPolarHBondContact O-CG 3.41Å; L385-Q389 PolarHBondContact O-N 3.17Å; L385-Y392 HydrophobicContact CD2-CD2 3.85Å; L385-Y392 HydrophobicContact CD2-CE2 3.45Å; L385-Y392 VanDerWaalsContact CD2-CE2 3.45Å
386	D	94.9	Very high	97.1	Very high	64 Å²	64	33.9 Å²	33.9	34%	0.342	18%	0.182	S	C	.	.	H	α-helix	trans	-54.3	-33.9	170.6	-83.4	-27	0	0	0	113	S382 K383 L384 I388 Q389	S382-D386 PolarHBondContact O-N 2.86Å; K383-D386 IonicContact NZ-OD2 3.23Å; K383-D386 PolarHBondContact NZ-OD2 2.97Å; L384-D386 VanDerWaalsContact C-N 3.33Å; L384-D386 PolarHBondContact O-N 3.3Å; D386-I388 VanDerWaalsContact C-N 3.32Å; D386-I388 PolarHBondContact O-N 3.41Å; D386-Q389 PolarHBondContact OD1-NE2 3.05Å
387	G	93.3	Very high	97.1	Very high	40 Å²	40	36.4 Å²	36.4	41%	0.412	20%	0.199	S	C	.	.	T	Hydrogen-bonded Turn	trans	-79	-8.4	178.4	0	0	0	0	0	115.3	L384 L385 S464	L384-G387 PolarHBondContact O-N 3.13Å; L384-G387 VanDerWaalsContact O-N 3.16Å; L385-G387 PolarHBondContact O-N 3.41Å; G387-S464 WeakPolarHBondContact O-CB 3.43Å; G387-S464 PolarHBondContact O-OG 3.21Å
388	I	96.2	Very high	97	Very high	1 Å²	1	36.4 Å²	36.4	1%	0.005	20%	0.199	C	C	.	.	T	Hydrogen-bonded Turn	trans	-144	29	-173	57	173.1	0	0	0	112.9	L385 D386 D390 N391 Y392 L439 F463 S464	L385-I388 HydrophobicContact CD2-CD1 4.35Å; L385-I388 HydrophobicContact CD2-CG1 4.4Å; L385-I388 CarbonylContact O-C 3.39Å; L385-I388 PolarHBondContact O-N 2.95Å; D386-I388 VanDerWaalsContact C-N 3.32Å; D386-I388 PolarHBondContact O-N 3.41Å; I388-D390 PolarHBondContact O-N 3.02Å; I388-D390 VanDerWaalsContact O-N 3.08Å; I388-N391 WeakPolarHBondContact O-CB 3.43Å; I388-N391 PolarHBondContact O-N 3.48Å; I388-Y392 HydrophobicContact CD1-CE2 3.79Å; I388-Y392 HydrophobicContact CG1-CE2 4.01Å; I388-L439 HydrophobicContact CD1-CD1 4.2Å; I388-L439 HydrophobicContact CD1-CD2 4.38Å; I388-F463 HydrophobicContact CD1-CE2 4.32Å; I388-F463 HydrophobicContact CD1-CZ 4.13Å; I388-F463 HydrophobicContact CG1-CZ 4.22Å; I388-F463 HydrophobicContact CG2-CE2 3.88Å; I388-F463 HydrophobicContact CG2-CZ 3.71Å; I388-S464 WeakPolarHBondContact CG2-OG 3.37Å
389	Q	94.9	Very high	97	Very high	92 Å²	92	36.3 Å²	36.3	43%	0.43	20%	0.199	S	C	.	.	G	3₁₀ helix	trans	-54.8	-33.1	-176.9	-62.1	-175.8	-0.8	0	0	112.6	L385 D386 N391 Y392 T393	L385-Q389 VanDerWaalsContact O-CG 3.27Å; L385-Q389 WeakPolarHBondContact O-CG 3.41Å; L385-Q389 PolarHBondContact O-N 3.17Å; D386-Q389 PolarHBondContact OD1-NE2 3.05Å; Q389-N391 PolarHBondContact O-N 3.02Å; Q389-Y392 PolarHBondContact O-N 3.23Å; Q389-Y392 VanDerWaalsContact O-N 3.16Å; Q389-T393 PolarHBondContact O-N 2.86Å
390	D	96.9	Very high	96.9	Very high	62 Å²	62	40 Å²	40	33%	0.332	22%	0.217	S	C	.	.	G	3₁₀ helix	trans	-67.2	-16.1	178.2	72.6	-35.7	0	0	0	114.8	I388 Y392 P397 G398 K402	I388-D390 PolarHBondContact O-N 3.02Å; I388-D390 VanDerWaalsContact O-N 3.08Å; D390-Y392 VanDerWaalsContact C-N 3.27Å; D390-Y392 PolarHBondContact O-N 2.74Å; D390-P397 WeakPolarHBondContact O-CD 3.22Å; D390-G398 WeakPolarHBondContact O-CA 3.42Å; D390-G398 PolarHBondContact O-N 2.94Å; D390-G398 WeakPolarHBondContact OD2-CA 3.44Å; D390-K402 IonicContact OD1-NZ 3.59Å; D390-K402 PolarHBondContact OD1-NZ 3.5Å
391	N	97.9	Very high	96.9	Very high	1 Å²	1	45 Å²	45	1%	0.005	24%	0.243	C	C	.	.	G	3₁₀ helix	trans	-69.8	-22.9	171.3	-80.6	8.8	0	0	0	112.9	I388 Q389 Q396 I399 K402 M436	I388-N391 WeakPolarHBondContact O-CB 3.43Å; I388-N391 PolarHBondContact O-N 3.48Å; Q389-N391 PolarHBondContact O-N 3.02Å; N391-Q396 VanDerWaalsContact O-CB 3.24Å; N391-Q396 WeakPolarHBondContact O-CB 3.5Å; N391-Q396 WeakPolarHBondContact O-CG 3.27Å; N391-Q396 PolarHBondContact O-NE2 3.16Å; N391-I399 HydrophobicContact CB-CD1 4.16Å; N391-I399 HydrophobicContact CB-CG1 3.77Å; N391-I399 WeakPolarHBondContact O-CD1 3.34Å; N391-I399 PolarHBondContact OD1-N 3Å; N391-K402 PolarHBondContact OD1-NZ 3.49Å; N391-M436 PolarHBondContact ND2-O 3.02Å
392	Y	97.9	Very high	96.9	Very high	2 Å²	2	46.2 Å²	46.2	1%	0.008	25%	0.249	C	C	.	.	T	Hydrogen-bonded Turn	trans	-123.7	-2.9	-167.2	-52	-68.3	0	0	0	114.3	S331 V334 I337 L385 I388 Q389 D390 N437	S331-Y392 VanDerWaalsContact CA-O 3.28Å; S331-Y392 WeakPolarHBondContact CA-O 3.39Å; S331-Y392 WeakPolarHBondContact CB-O 3.12Å; S331-Y392 PolarHBondContact OG-O 3.15Å; V334-Y392 HydrophobicContact CB-CD1 4.15Å; V334-Y392 HydrophobicContact CG1-CD1 4.17Å; V334-Y392 WeakPolarHBondContact CG2-O 3.3Å; I337-Y392 HydrophobicContact CD1-CD1 3.78Å; I337-Y392 HydrophobicContact CD1-CD2 4.31Å; I337-Y392 HydrophobicContact CD1-CE1 4.36Å; I337-Y392 HydrophobicContact CD1-CG 3.76Å; I337-Y392 HydrophobicContact CG1-CD1 3.72Å; I337-Y392 HydrophobicContact CG1-CE1 3.8Å; I337-Y392 HydrophobicContact CG1-CG 4.12Å; L385-Y392 HydrophobicContact CD2-CD2 3.85Å; L385-Y392 HydrophobicContact CD2-CE2 3.45Å; L385-Y392 VanDerWaalsContact CD2-CE2 3.45Å; I388-Y392 HydrophobicContact CD1-CE2 3.79Å; I388-Y392 HydrophobicContact CG1-CE2 4.01Å; Q389-Y392 PolarHBondContact O-N 3.23Å; Q389-Y392 VanDerWaalsContact O-N 3.16Å; D390-Y392 VanDerWaalsContact C-N 3.27Å; D390-Y392 PolarHBondContact O-N 2.74Å; Y392-N437 PolarHBondContact OH-O 3.34Å
393	T	97.4	Very high	96.9	Very high	40 Å²	40	46.2 Å²	46.2	25%	0.245	25%	0.248	C	C	.	.	S	Bend	trans	-69.8	169.8	169.3	53.8	0	0	0	0	111.6	A330 Q389 A395 Q396	A330-T393 HydrophobicContact CB-CG2 4.26Å; A330-T393 WeakPolarHBondContact O-CA 3.34Å; Q389-T393 PolarHBondContact O-N 2.86Å; T393-A395 PolarHBondContact O-N 2.96Å; T393-Q396 WeakPolarHBondContact O-CA 3.3Å; T393-Q396 PolarHBondContact O-N 2.97Å
394	F	96.4	Very high	97	Very high	161 Å²	161	48.3 Å²	48.3	71%	0.706	26%	0.258	S	S	*	.	T	Hydrogen-bonded Turn	trans	-48.6	127.8	-178.3	-179.8	-100.3	0	0	0	113.4	Q396	F394-Q396 PolarHBondContact O-N 2.73Å
395	A	95.3	Very high	97	Very high	60 Å²	60	49.5 Å²	49.5	50%	0.496	27%	0.269	S	S	.	.	T	Hydrogen-bonded Turn	trans	64	7.5	-174.1	0	0	0	0	0	116.5	T393 Q400	T393-A395 PolarHBondContact O-N 2.96Å; A395-Q400 PolarHBondContact O-NE2 3.23Å
396	Q	97.3	Very high	97	Very high	39 Å²	39	49.4 Å²	49.4	18%	0.182	27%	0.269	C	S	.	.			trans	51.2	50.9	169.8	-55.9	-170.8	-97.9	0	0	114.5	N391 T393 F394 G398 I399 Q400 N437	N391-Q396 VanDerWaalsContact O-CB 3.24Å; N391-Q396 WeakPolarHBondContact O-CB 3.5Å; N391-Q396 WeakPolarHBondContact O-CG 3.27Å; N391-Q396 PolarHBondContact O-NE2 3.16Å; T393-Q396 WeakPolarHBondContact O-CA 3.3Å; T393-Q396 PolarHBondContact O-N 2.97Å; F394-Q396 PolarHBondContact O-N 2.73Å; Q396-G398 PolarHBondContact O-N 3.32Å; Q396-I399 HydrophobicContact CB-CD1 4.2Å; Q396-I399 VanDerWaalsContact NE2-CD1 3.27Å; Q396-I399 PolarHBondContact O-N 3.21Å; Q396-I399 VanDerWaalsContact O-N 3.11Å; Q396-Q400 PolarHBondContact O-N 3.37Å; Q396-N437 PolarHBondContact NE2-OD1 3.46Å
397	P	97.6	Very high	97.2	Very high	54 Å²	54	49.9 Å²	49.9	35%	0.351	27%	0.269	S	S	.	.	H	α-helix	trans	-60.2	-32.2	-173.2	26.1	-35.6	0	0	0	113.2	D390 I399 Q400 N401	D390-P397 WeakPolarHBondContact O-CD 3.22Å; P397-I399 VanDerWaalsContact C-N 3.31Å; P397-I399 PolarHBondContact O-N 3.41Å; P397-Q400 PolarHBondContact O-N 3.28Å; P397-N401 WeakPolarHBondContact O-CB 3.42Å; P397-N401 PolarHBondContact O-N 3.25Å; P397-N401 PolarHBondContact O-ND2 2.68Å
398	G	97.8	Very high	97.4	Very high	0 Å²	0	51.1 Å²	51.1	0%	0	26%	0.264	C	S	.	.	H	α-helix	trans	-60	-39.3	176.5	0	0	0	0	0	113.2	D390 Q396 K402	D390-G398 WeakPolarHBondContact O-CA 3.42Å; D390-G398 PolarHBondContact O-N 2.94Å; D390-G398 WeakPolarHBondContact OD2-CA 3.44Å; Q396-G398 PolarHBondContact O-N 3.32Å; G398-K402 WeakPolarHBondContact O-CB 3.4Å; G398-K402 WeakPolarHBondContact O-CD 3.25Å; G398-K402 WeakPolarHBondContact O-CG 3.29Å; G398-K402 PolarHBondContact O-N 3.22Å
399	I	97.9	Very high	97.4	Very high	0 Å²	0	51.2 Å²	51.2	0%	0	26%	0.264	C	S	.	.	H	α-helix	trans	-69.6	-45.3	177.1	-62.5	177.5	0	0	0	110.4	N391 Q396 P397 N401 K402 V403 F433 M436 N437	N391-I399 HydrophobicContact CB-CD1 4.16Å; N391-I399 HydrophobicContact CB-CG1 3.77Å; N391-I399 WeakPolarHBondContact O-CD1 3.34Å; N391-I399 PolarHBondContact OD1-N 3Å; Q396-I399 HydrophobicContact CB-CD1 4.2Å; Q396-I399 VanDerWaalsContact NE2-CD1 3.27Å; Q396-I399 PolarHBondContact O-N 3.21Å; Q396-I399 VanDerWaalsContact O-N 3.11Å; P397-I399 VanDerWaalsContact C-N 3.31Å; P397-I399 PolarHBondContact O-N 3.41Å; I399-N401 VanDerWaalsContact C-N 3.29Å; I399-N401 PolarHBondContact O-N 3.14Å; I399-K402 PolarHBondContact O-N 3.1Å; I399-V403 HydrophobicContact CG2-CG2 4.1Å; I399-V403 WeakPolarHBondContact O-CB 3.49Å; I399-V403 WeakPolarHBondContact O-CG2 3.45Å; I399-V403 PolarHBondContact O-N 3.27Å; I399-F433 HydrophobicContact CB-CE2 4.43Å; I399-F433 HydrophobicContact CD1-CE2 4.15Å; I399-F433 HydrophobicContact CD1-CZ 4.25Å; I399-F433 HydrophobicContact CG2-CD2 3.48Å; I399-F433 VanDerWaalsContact CG2-CD2 3.48Å; I399-F433 HydrophobicContact CG2-CE2 3.81Å; I399-F433 HydrophobicContact CG2-CG 4.19Å; I399-M436 HydrophobicContact CG2-CB 4.06Å; I399-N437 HydrophobicContact CD1-CB 3.71Å; I399-N437 WeakPolarHBondContact CD1-OD1 3.21Å
400	Q	97.9	Very high	97.5	Very high	108 Å²	108	46.8 Å²	46.8	51%	0.505	24%	0.244	S	C	.	.	H	α-helix	trans	-58.6	-43.4	177.8	-58.8	-174.1	31.9	0	0	111.3	A395 Q396 P397 K404	A395-Q400 PolarHBondContact O-NE2 3.23Å; Q396-Q400 PolarHBondContact O-N 3.37Å; P397-Q400 PolarHBondContact O-N 3.28Å; Q400-K404 WeakPolarHBondContact O-CB 3.33Å; Q400-K404 PolarHBondContact O-N 3.33Å
401	N	98	Very high	97.5	Very high	103 Å²	103	45.3 Å²	45.3	55%	0.551	24%	0.238	S	C	*	.	H	α-helix	trans	-63.5	-45.4	175.7	-70.2	-27.2	0	0	0	112.1	P397 I399 K404 A405	P397-N401 WeakPolarHBondContact O-CB 3.42Å; P397-N401 PolarHBondContact O-N 3.25Å; P397-N401 PolarHBondContact O-ND2 2.68Å; I399-N401 VanDerWaalsContact C-N 3.29Å; I399-N401 PolarHBondContact O-N 3.14Å; N401-K404 PolarHBondContact O-N 2.92Å; N401-A405 WeakPolarHBondContact O-CB 3.27Å; N401-A405 PolarHBondContact O-N 2.82Å
402	K	97.9	Very high	97.3	Very high	26 Å²	26	48.9 Å²	48.9	11%	0.113	25%	0.251	C	S	.	.	H	α-helix	trans	-68.2	-38.5	-179.8	-71.9	162.8	-169.3	159	0	112.7	D390 N391 G398 I399 A405 L406 M436 S464 L468	D390-K402 IonicContact OD1-NZ 3.59Å; D390-K402 PolarHBondContact OD1-NZ 3.5Å; N391-K402 PolarHBondContact OD1-NZ 3.49Å; G398-K402 WeakPolarHBondContact O-CB 3.4Å; G398-K402 WeakPolarHBondContact O-CD 3.25Å; G398-K402 WeakPolarHBondContact O-CG 3.29Å; G398-K402 PolarHBondContact O-N 3.22Å; I399-K402 PolarHBondContact O-N 3.1Å; K402-A405 PolarHBondContact O-N 3.48Å; K402-L406 PolarHBondContact O-N 2.86Å; K402-M436 HydrophobicContact CB-CE 4.26Å; K402-M436 HydrophobicContact CB-CG 4.08Å; K402-M436 HydrophobicContact CB-SD 3.73Å; K402-S464 PolarHBondContact NZ-OG 3.49Å; K402-L468 WeakPolarHBondContact O-CD1 3.38Å
403	V	98.5	Very high	97.2	Very high	9 Å²	9	50.8 Å²	50.8	6%	0.055	26%	0.261	C	S	.	.	H	α-helix	trans	-64.4	-43.3	173.5	170.5	0	0	0	0	111.2	I399 L406 E407 L429 A432 M436	I399-V403 HydrophobicContact CG2-CG2 4.1Å; I399-V403 WeakPolarHBondContact O-CB 3.49Å; I399-V403 WeakPolarHBondContact O-CG2 3.45Å; I399-V403 PolarHBondContact O-N 3.27Å; V403-L406 WeakPolarHBondContact O-CB 3.16Å; V403-L406 PolarHBondContact O-N 2.93Å; V403-E407 PolarHBondContact O-N 3.42Å; V403-L429 HydrophobicContact CB-CD1 4.43Å; V403-L429 HydrophobicContact CG1-CB 4.3Å; V403-L429 HydrophobicContact CG1-CD1 4.11Å; V403-L429 HydrophobicContact CG2-CD1 4.3Å; V403-A432 HydrophobicContact CG1-CB 4.46Å; V403-A432 HydrophobicContact CG2-CB 4.13Å; V403-M436 HydrophobicContact CG2-CG 4.07Å
404	K	98.2	Very high	97.1	Very high	141 Å²	141	49.4 Å²	49.4	61%	0.613	25%	0.252	S	S	*	.	H	α-helix	trans	-65.9	-38.7	175.4	-176.2	179.3	176.7	-177.2	0	112.5	Q400 N401 L406 E407 E408	Q400-K404 WeakPolarHBondContact O-CB 3.33Å; Q400-K404 PolarHBondContact O-N 3.33Å; N401-K404 PolarHBondContact O-N 2.92Å; K404-L406 VanDerWaalsContact C-N 3.26Å; K404-L406 PolarHBondContact O-N 2.96Å; K404-E407 PolarHBondContact O-N 3.12Å; K404-E408 PolarHBondContact O-N 3.36Å
405	A	97.6	Very high	97.1	Very high	35 Å²	35	45.4 Å²	45.4	29%	0.289	24%	0.241	S	C	.	.	H	α-helix	trans	-63.9	-33.1	173.4	0	0	0	0	0	111.6	N401 K402 L409 L468	N401-A405 WeakPolarHBondContact O-CB 3.27Å; N401-A405 PolarHBondContact O-N 2.82Å; K402-A405 PolarHBondContact O-N 3.48Å; A405-L409 WeakPolarHBondContact O-CB 3.3Å; A405-L409 PolarHBondContact O-N 2.94Å; A405-L468 HydrophobicContact CB-CD1 3.95Å; A405-L468 HydrophobicContact CB-CD2 3.81Å
406	L	98.3	Very high	97.3	Very high	0 Å²	0	46.9 Å²	46.9	0%	0	24%	0.241	C	C	.	.	H	α-helix	trans	-69.4	-43	175.5	-177.2	65.1	0	0	0	111	K402 V403 K404 E408 L409 V410 Y428 A432 W435 M436 L468 C471 A472	K402-L406 PolarHBondContact O-N 2.86Å; V403-L406 WeakPolarHBondContact O-CB 3.16Å; V403-L406 PolarHBondContact O-N 2.93Å; K404-L406 VanDerWaalsContact C-N 3.26Å; K404-L406 PolarHBondContact O-N 2.96Å; L406-E408 PolarHBondContact O-N 2.95Å; L406-L409 PolarHBondContact O-N 3.19Å; L406-V410 HydrophobicContact CD1-CG2 3.99Å; L406-V410 HydrophobicContact CG-CG2 4.32Å; L406-V410 WeakPolarHBondContact O-CB 3.37Å; L406-V410 WeakPolarHBondContact O-CG2 3.47Å; L406-V410 PolarHBondContact O-N 3.06Å; L406-Y428 HydrophobicContact CD2-CD1 4.48Å; L406-Y428 HydrophobicContact CG-CD1 4.38Å; L406-A432 HydrophobicContact CD2-CB 3.72Å; L406-W435 HydrophobicContact CD2-CE3 4.48Å; L406-M436 HydrophobicContact CB-CE 4.16Å; L406-M436 HydrophobicContact CD2-CE 4.1Å; L406-L468 HydrophobicContact CB-CD1 3.86Å; L406-L468 HydrophobicContact CD1-CD1 4.4Å; L406-C471 HydrophobicContact CD1-CB 3.89Å; L406-C471 HydrophobicContact CD2-CB 4.04Å; L406-A472 HydrophobicContact CD1-CB 3.94Å
407	E	98.3	Very high	97.3	Very high	74 Å²	74	45 Å²	45	35%	0.346	23%	0.232	S	C	.	.	H	α-helix	trans	-56.6	-49.1	172.9	176.1	177.6	-168.4	0	0	111.6	V403 K404 S411 H418 Y428	V403-E407 PolarHBondContact O-N 3.42Å; K404-E407 PolarHBondContact O-N 3.12Å; E407-S411 VanDerWaalsContact O-CB 3.28Å; E407-S411 WeakPolarHBondContact O-CB 3.49Å; E407-S411 PolarHBondContact O-N 2.99Å; E407-S411 PolarHBondContact O-OG 3.04Å; E407-H418 IonicContact OE1-CE1 3.38Å; E407-Y428 HydrophobicContact CB-CD1 4.18Å; E407-Y428 HydrophobicContact CB-CD2 3.71Å; E407-Y428 HydrophobicContact CB-CE1 4.34Å; E407-Y428 HydrophobicContact CB-CE2 3.93Å; E407-Y428 HydrophobicContact CB-CG 3.87Å; E407-Y428 HydrophobicContact CG-CD2 3.71Å; E407-Y428 HydrophobicContact CG-CE2 3.64Å; E407-Y428 HydrophobicContact CG-CG 4.39Å
408	E	97.1	Very high	97.3	Very high	65 Å²	65	43.1 Å²	43.1	30%	0.304	22%	0.218	S	C	.	.	H	α-helix	trans	-66.8	-38.6	179.5	178.3	152	-127.8	0	0	112	K404 L406 S411 R412 K530	K404-E408 PolarHBondContact O-N 3.36Å; L406-E408 PolarHBondContact O-N 2.95Å; E408-S411 PolarHBondContact O-OG 2.94Å; E408-R412 WeakPolarHBondContact O-CG 3.5Å; E408-R412 PolarHBondContact O-N 2.7Å; E408-K530 IonicContact OE1-NZ 3.62Å; E408-K530 PolarHBondContact OE1-NZ 3.46Å
409	L	96.6	Very high	97.4	Very high	3 Å²	3	47.1 Å²	47.1	2%	0.016	24%	0.24	C	C	.	.	H	α-helix	trans	-64.8	-50.9	175.9	-177.9	59.4	0	0	0	111.5	A405 L406 S411 R412 I413 L468 Y469 A472 F522	A405-L409 WeakPolarHBondContact O-CB 3.3Å; A405-L409 PolarHBondContact O-N 2.94Å; L406-L409 PolarHBondContact O-N 3.19Å; L409-S411 VanDerWaalsContact C-N 3.33Å; L409-S411 PolarHBondContact O-N 3.21Å; L409-R412 PolarHBondContact O-N 3.11Å; L409-R412 VanDerWaalsContact O-N 3.1Å; L409-I413 HydrophobicContact CD1-CD1 3.7Å; L409-I413 HydrophobicContact CD1-CG1 4.3Å; L409-I413 HydrophobicContact CD2-CD1 4.48Å; L409-I413 HydrophobicContact CG-CD1 3.66Å; L409-I413 WeakPolarHBondContact O-CG1 3.38Å; L409-I413 PolarHBondContact O-N 2.76Å; L409-I413 VanDerWaalsContact O-N 3.12Å; L409-L468 HydrophobicContact CD2-CD2 4.22Å; L409-L468 HydrophobicContact CD2-CG 3.89Å; L409-Y469 HydrophobicContact CD1-CD1 4.29Å; L409-Y469 HydrophobicContact CD1-CE1 3.96Å; L409-Y469 HydrophobicContact CD2-CD1 3.63Å; L409-Y469 HydrophobicContact CD2-CE1 3.83Å; L409-Y469 HydrophobicContact CD2-CG 4.29Å; L409-A472 HydrophobicContact CD2-CB 3.76Å; L409-A472 HydrophobicContact CG-CB 4.21Å; L409-F522 HydrophobicContact CD1-CB 3.98Å; L409-F522 HydrophobicContact CD1-CG 4.32Å
410	V	97.3	Very high	97.4	Very high	0 Å²	0	48.4 Å²	48.4	0%	0	25%	0.246	C	C	.	.	H	α-helix	trans	-63.6	-37.9	177.9	175.9	0	0	0	0	111.2	L406 R412 I413 D414 I417 Y428 A472	L406-V410 HydrophobicContact CD1-CG2 3.99Å; L406-V410 HydrophobicContact CG-CG2 4.32Å; L406-V410 WeakPolarHBondContact O-CB 3.37Å; L406-V410 WeakPolarHBondContact O-CG2 3.47Å; L406-V410 PolarHBondContact O-N 3.06Å; V410-R412 PolarHBondContact O-N 2.97Å; V410-R412 VanDerWaalsContact O-N 3.09Å; V410-I413 PolarHBondContact O-N 3.02Å; V410-D414 CarbonylContact O-C 3.55Å; V410-D414 PolarHBondContact O-N 2.69Å; V410-I417 HydrophobicContact CG1-CG2 4.01Å; V410-Y428 HydrophobicContact CB-CE1 4.13Å; V410-Y428 HydrophobicContact CG1-CE1 4.41Å; V410-Y428 WeakPolarHBondContact CG1-OH 3.43Å; V410-Y428 HydrophobicContact CG2-CE1 4.3Å; V410-A472 HydrophobicContact CG2-CB 4.35Å
411	S	96.9	Very high	97.4	Very high	31 Å²	31	43.3 Å²	43.3	22%	0.217	22%	0.222	C	C	.	.	H	α-helix	trans	-61.4	-18.9	175	78.3	0	0	0	0	114.8	E407 E408 L409 V415	E407-S411 VanDerWaalsContact O-CB 3.28Å; E407-S411 WeakPolarHBondContact O-CB 3.49Å; E407-S411 PolarHBondContact O-N 2.99Å; E407-S411 PolarHBondContact O-OG 3.04Å; E408-S411 PolarHBondContact O-OG 2.94Å; L409-S411 VanDerWaalsContact C-N 3.33Å; L409-S411 PolarHBondContact O-N 3.21Å; S411-V415 WeakPolarHBondContact O-CG2 3.49Å
412	R	94.1	Very high	97.4	Very high	75 Å²	75	44.4 Å²	44.4	28%	0.283	22%	0.222	S	C	.	.	H	α-helix	trans	-96.6	-30.5	176.8	-66.8	-177.9	-56	158.8	9.9	112.8	E408 L409 V410 F522 A525	E408-R412 WeakPolarHBondContact O-CG 3.5Å; E408-R412 PolarHBondContact O-N 2.7Å; L409-R412 PolarHBondContact O-N 3.11Å; L409-R412 VanDerWaalsContact O-N 3.1Å; V410-R412 PolarHBondContact O-N 2.97Å; V410-R412 VanDerWaalsContact O-N 3.09Å; R412-F522 HydrophobicContact CB-CD1 4.44Å; R412-F522 HydrophobicContact CB-CE1 4.16Å; R412-A525 PolarHBondContact NH1-O 3.28Å
413	I	94.6	Very high	97.5	Very high	42 Å²	42	49.8 Å²	49.8	22%	0.215	25%	0.245	C	C	.	.	H	α-helix	trans	-87.1	-47	-179.5	-56.4	158.3	0	0	0	111.2	L409 V410 A472 I476 L518 F522	L409-I413 HydrophobicContact CD1-CD1 3.7Å; L409-I413 HydrophobicContact CD1-CG1 4.3Å; L409-I413 HydrophobicContact CD2-CD1 4.48Å; L409-I413 HydrophobicContact CG-CD1 3.66Å; L409-I413 WeakPolarHBondContact O-CG1 3.38Å; L409-I413 PolarHBondContact O-N 2.76Å; L409-I413 VanDerWaalsContact O-N 3.12Å; V410-I413 PolarHBondContact O-N 3.02Å; I413-A472 HydrophobicContact CD1-CB 4.23Å; I413-I476 HydrophobicContact CB-CD1 4.32Å; I413-I476 HydrophobicContact CD1-CD1 4.3Å; I413-I476 HydrophobicContact CG2-CD1 3.57Å; I413-L518 HydrophobicContact CD1-CD1 4.1Å; I413-L518 HydrophobicContact CD1-CD2 3.86Å; I413-L518 HydrophobicContact CD1-CG 4.43Å; I413-L518 HydrophobicContact CG1-CD2 4.17Å; I413-L518 HydrophobicContact CG2-CD2 3.95Å; I413-F522 HydrophobicContact CB-CZ 4.44Å; I413-F522 HydrophobicContact CG1-CD1 4.49Å; I413-F522 HydrophobicContact CG1-CD2 4.05Å; I413-F522 HydrophobicContact CG1-CE1 4.14Å; I413-F522 HydrophobicContact CG1-CE2 3.68Å; I413-F522 HydrophobicContact CG1-CG 4.45Å; I413-F522 HydrophobicContact CG1-CZ 3.72Å
414	D	95.7	Very high	97.5	Very high	11 Å²	11	51.1 Å²	51.1	6%	0.059	25%	0.249	C	C	.	.			trans	-137.5	85.1	-171.5	-158.6	-34.9	0	0	0	111.7	V410 D416 I417 H418 R479	V410-D414 CarbonylContact O-C 3.55Å; V410-D414 PolarHBondContact O-N 2.69Å; D414-D416 VanDerWaalsContact C-N 3.25Å; D414-D416 PolarHBondContact O-N 2.99Å; D414-D416 PolarHBondContact OD1-N 2.84Å; D414-I417 HydrophobicContact CB-CB 4.16Å; D414-I417 HydrophobicContact CB-CD1 4.13Å; D414-I417 HydrophobicContact CB-CG1 4.29Å; D414-I417 PolarHBondContact O-N 3.31Å; D414-I417 PolarHBondContact OD1-N 2.83Å; D414-I417 VanDerWaalsContact OD1-N 3.15Å; D414-I417 VanDerWaalsContact OD2-CD1 3.28Å; D414-I417 WeakPolarHBondContact OD2-CD1 3.31Å; D414-H418 PolarHBondContact O-N 3.3Å; D414-H418 VanDerWaalsContact O-N 3.12Å; D414-R479 IonicContact OD1-CZ 2.7Å; D414-R479 IonicContact OD1-NE 3.02Å; D414-R479 IonicContact OD1-NH2 3.68Å; D414-R479 PolarHBondContact OD1-NH2 3.48Å; D414-R479 IonicContact OD2-CZ 3.15Å; D414-R479 IonicContact OD2-NE 2.86Å; D414-R479 PolarHBondContact OD2-NE 2.86Å; D414-R479 IonicContact OD2-NH2 3.6Å; D414-R479 PolarHBondContact OD2-NH2 3.42Å
415	V	97.1	Very high	97.5	Very high	77 Å²	77	52.1 Å²	52.1	47%	0.467	26%	0.256	S	S	.	.	H	α-helix	trans	-62.8	-31.6	179.9	176.5	0	0	0	0	111.8	S411 N419	S411-V415 WeakPolarHBondContact O-CG2 3.49Å; V415-N419 VanDerWaalsContact CG1-ND2 3.33Å; V415-N419 WeakPolarHBondContact CG1-ND2 3.19Å; V415-N419 VanDerWaalsContact O-CB 3.26Å; V415-N419 WeakPolarHBondContact O-CB 3.19Å; V415-N419 PolarHBondContact O-N 3.26Å; V415-N419 PolarHBondContact O-ND2 2.88Å
416	D	98.1	Very high	97.5	Very high	91 Å²	91	50.8 Å²	50.8	49%	0.487	25%	0.245	S	C	.	.	H	α-helix	trans	-67.8	-49	179.7	-61.4	-29.7	0	0	0	110.5	D414 H418 N419 H420 R479 L483	D414-D416 VanDerWaalsContact C-N 3.25Å; D414-D416 PolarHBondContact O-N 2.99Å; D414-D416 PolarHBondContact OD1-N 2.84Å; D416-H418 PolarHBondContact O-N 2.64Å; D416-N419 PolarHBondContact O-N 3.38Å; D416-H420 WeakPolarHBondContact O-CB 3.35Å; D416-H420 PolarHBondContact O-N 3Å; D416-R479 IonicContact OD2-CZ 3.26Å; D416-R479 IonicContact OD2-NH1 3.2Å; D416-R479 IonicContact OD2-NH2 3.7Å; D416-R479 PolarHBondContact OD2-NH2 3.49Å; D416-L483 HydrophobicContact CB-CD1 4.34Å; D416-L483 HydrophobicContact CB-CD2 4.34Å
417	I	97.9	Very high	97.5	Very high	0 Å²	0	56.6 Å²	56.6	0%	0	27%	0.271	C	S	.	.	H	α-helix	trans	-57.7	-49	175.6	-72.5	-179	0	0	0	110.4	V410 D414 N419 H420 F421 L475 R479 I482 L483	V410-I417 HydrophobicContact CG1-CG2 4.01Å; D414-I417 HydrophobicContact CB-CB 4.16Å; D414-I417 HydrophobicContact CB-CD1 4.13Å; D414-I417 HydrophobicContact CB-CG1 4.29Å; D414-I417 PolarHBondContact O-N 3.31Å; D414-I417 PolarHBondContact OD1-N 2.83Å; D414-I417 VanDerWaalsContact OD1-N 3.15Å; D414-I417 VanDerWaalsContact OD2-CD1 3.28Å; D414-I417 WeakPolarHBondContact OD2-CD1 3.31Å; I417-N419 VanDerWaalsContact C-N 3.34Å; I417-N419 PolarHBondContact O-N 3.3Å; I417-H420 WeakPolarHBondContact O-CB 3.15Å; I417-H420 PolarHBondContact O-N 3.01Å; I417-H420 VanDerWaalsContact O-N 3.15Å; I417-F421 HydrophobicContact CG2-CD2 4.38Å; I417-F421 HydrophobicContact CG2-CE1 4.03Å; I417-F421 HydrophobicContact CG2-CE2 3.87Å; I417-F421 HydrophobicContact CG2-CZ 3.7Å; I417-F421 WeakPolarHBondContact O-CG 3.49Å; I417-F421 PolarHBondContact O-N 2.62Å; I417-L475 HydrophobicContact CD1-CD2 3.99Å; I417-L475 HydrophobicContact CG2-CD2 3.47Å; I417-L475 VanDerWaalsContact CG2-CD2 3.47Å; I417-R479 HydrophobicContact CD1-CB 3.98Å; I417-R479 HydrophobicContact CD1-CG 3.99Å; I417-R479 HydrophobicContact CG1-CG 4.29Å; I417-I482 HydrophobicContact CG1-CG2 4.45Å; I417-L483 HydrophobicContact CG1-CD2 4.34Å; I417-L483 HydrophobicContact CG1-CG 4.41Å
418	H	98.4	Very high	97.5	Very high	15 Å²	15	53.6 Å²	53.6	7%	0.069	26%	0.257	C	S	.	.	H	α-helix	trans	-63	-39.1	-178.3	178.5	88.1	0	0	0	112.4	E407 D414 D416 K422 Y428	E407-H418 IonicContact OE1-CE1 3.38Å; D414-H418 PolarHBondContact O-N 3.3Å; D414-H418 VanDerWaalsContact O-N 3.12Å; D416-H418 PolarHBondContact O-N 2.64Å; H418-K422 VanDerWaalsContact NE2-CE 3.26Å; H418-K422 WeakPolarHBondContact NE2-CE 3.42Å; H418-K422 PolarHBondContact NE2-NZ 3.44Å; H418-K422 PolarHBondContact O-N 3.29Å; H418-Y428 AromaticContact ND1-CE2 3.79Å; H418-Y428 AromaticContact ND1-CZ 3.86Å; H418-Y428 PolarHBondContact ND1-OH 2.76Å
419	N	98.4	Very high	97.5	Very high	83 Å²	83	54.6 Å²	54.6	44%	0.444	26%	0.264	S	S	.	.	H	α-helix	trans	-73	-31.5	174.3	-72.9	-23.2	0	0	0	112.7	V415 D416 I417 K422 K423	V415-N419 VanDerWaalsContact CG1-ND2 3.33Å; V415-N419 WeakPolarHBondContact CG1-ND2 3.19Å; V415-N419 VanDerWaalsContact O-CB 3.26Å; V415-N419 WeakPolarHBondContact O-CB 3.19Å; V415-N419 PolarHBondContact O-N 3.26Å; V415-N419 PolarHBondContact O-ND2 2.88Å; D416-N419 PolarHBondContact O-N 3.38Å; I417-N419 VanDerWaalsContact C-N 3.34Å; I417-N419 PolarHBondContact O-N 3.3Å; N419-K422 PolarHBondContact O-N 3.2Å; N419-K423 WeakPolarHBondContact O-CB 3.46Å; N419-K423 PolarHBondContact O-N 3.45Å
420	H	98.5	Very high	97.6	Very high	27 Å²	27	57.2 Å²	57.2	13%	0.125	28%	0.276	C	S	.	.	H	α-helix	trans	-66.7	-43.5	176	-175.8	111.1	0	0	0	111.2	D416 I417 K422 K423 Y424 I482 L483 M485	D416-H420 WeakPolarHBondContact O-CB 3.35Å; D416-H420 PolarHBondContact O-N 3Å; I417-H420 WeakPolarHBondContact O-CB 3.15Å; I417-H420 PolarHBondContact O-N 3.01Å; I417-H420 VanDerWaalsContact O-N 3.15Å; H420-K422 PolarHBondContact O-N 2.87Å; H420-K423 WeakPolarHBondContact O-CB 3.38Å; H420-K423 PolarHBondContact O-N 3.45Å; H420-Y424 AromaticContact CD2-CD2 3.71Å; H420-Y424 AromaticContact ND1-CE2 3.98Å; H420-Y424 AromaticContact NE2-CE2 3.79Å; H420-Y424 WeakPolarHBondContact O-CD2 3.2Å; H420-Y424 PolarHBondContact O-N 3.38Å; H420-Y424 VanDerWaalsContact O-N 3.16Å; H420-I482 PolarHBondContact NE2-O 2.83Å; H420-L483 HydrophobicContact CB-CD2 3.68Å; H420-L483 WeakPolarHBondContact CE1-CD2 3.36Å; H420-L483 WeakPolarHBondContact NE2-CA 3.28Å; H420-L483 PolarHBondContact NE2-O 2.97Å; H420-M485 PolarHBondContact NE2-O 2.7Å
421	F	98.6	Very high	97.7	Very high	1 Å²	1	57.4 Å²	57.4	0%	0.004	28%	0.277	C	S	.	.	H	α-helix	trans	-58.4	-45.7	171.8	-68.3	-6.5	0	0	0	111.8	I417 K423 Y424 E425 V426 Y428 F431 L475 I482 L491 L495	I417-F421 HydrophobicContact CG2-CD2 4.38Å; I417-F421 HydrophobicContact CG2-CE1 4.03Å; I417-F421 HydrophobicContact CG2-CE2 3.87Å; I417-F421 HydrophobicContact CG2-CZ 3.7Å; I417-F421 WeakPolarHBondContact O-CG 3.49Å; I417-F421 PolarHBondContact O-N 2.62Å; F421-K423 PolarHBondContact O-N 2.92Å; F421-Y424 CarbonylContact O-C 3.53Å; F421-Y424 PolarHBondContact O-N 2.98Å; F421-E425 PolarHBondContact O-N 3.07Å; F421-V426 HydrophobicContact CB-CB 4.43Å; F421-V426 PolarHBondContact O-N 3.43Å; F421-Y428 HydrophobicContact CD2-CD2 4.43Å; F421-Y428 HydrophobicContact CD2-CE1 4.06Å; F421-Y428 AromaticContact CD2-CE2 3.76Å; F421-Y428 HydrophobicContact CD2-CE2 3.76Å; F421-Y428 AromaticContact CD2-CZ 3.55Å; F421-Y428 AromaticContact CE2-CE1 3.92Å; F421-Y428 HydrophobicContact CE2-CE1 3.92Å; F421-Y428 HydrophobicContact CE2-CE2 4.45Å; F421-Y428 AromaticContact CE2-CZ 3.85Å; F421-F431 HydrophobicContact CD2-CZ 4.47Å; F421-F431 HydrophobicContact CE2-CE1 4.1Å; F421-F431 AromaticContact CE2-CZ 3.73Å; F421-F431 HydrophobicContact CE2-CZ 3.73Å; F421-F431 HydrophobicContact CZ-CE1 4.47Å; F421-F431 HydrophobicContact CZ-CZ 4.18Å; F421-L475 HydrophobicContact CE2-CD1 3.99Å; F421-L475 HydrophobicContact CE2-CD2 4.2Å; F421-L475 HydrophobicContact CZ-CD1 4.08Å; F421-L475 HydrophobicContact CZ-CD2 3.87Å; F421-L475 HydrophobicContact CZ-CG 4.32Å; F421-I482 HydrophobicContact CE1-CG2 3.71Å; F421-I482 HydrophobicContact CZ-CG2 4.45Å; F421-L491 HydrophobicContact CD1-CD2 4.13Å; F421-L491 HydrophobicContact CE1-CD1 4.22Å; F421-L495 HydrophobicContact CE1-CD1 3.81Å; F421-L495 HydrophobicContact CE1-CD2 4.36Å; F421-L495 HydrophobicContact CZ-CD1 3.94Å; F421-L495 HydrophobicContact CZ-CD2 3.99Å
422	K	98.1	Very high	97.7	Very high	126 Å²	126	55.9 Å²	55.9	55%	0.548	27%	0.267	S	S	.	.	H	α-helix	trans	-61.1	-40.8	174.5	-78.3	174.4	167.1	170.3	0	113.3	H418 N419 H420 Y424 E425	H418-K422 VanDerWaalsContact NE2-CE 3.26Å; H418-K422 WeakPolarHBondContact NE2-CE 3.42Å; H418-K422 PolarHBondContact NE2-NZ 3.44Å; H418-K422 PolarHBondContact O-N 3.29Å; N419-K422 PolarHBondContact O-N 3.2Å; H420-K422 PolarHBondContact O-N 2.87Å; K422-Y424 VanDerWaalsContact C-N 3.26Å; K422-Y424 PolarHBondContact O-N 2.95Å; K422-E425 PolarHBondContact O-N 2.98Å
423	K	98.4	Very high	97.9	Very high	139 Å²	139	55.8 Å²	55.8	60%	0.604	27%	0.268	S	S	*	.	H	α-helix	trans	-62.2	-32.9	178.5	-178.2	-169.2	173.6	-159.2	0	112.5	N419 H420 F421	N419-K423 WeakPolarHBondContact O-CB 3.46Å; N419-K423 PolarHBondContact O-N 3.45Å; H420-K423 WeakPolarHBondContact O-CB 3.38Å; H420-K423 PolarHBondContact O-N 3.45Å; F421-K423 PolarHBondContact O-N 2.92Å
424	Y	98.5	Very high	98.1	Very high	38 Å²	38	55.9 Å²	55.9	15%	0.149	27%	0.266	C	S	.	.	T	Hydrogen-bonded Turn	trans	-108.6	16.9	-178.2	-65.6	-65.3	0	0	0	113.6	H420 F421 K422 V426 V486 F488 L491	H420-Y424 AromaticContact CD2-CD2 3.71Å; H420-Y424 AromaticContact ND1-CE2 3.98Å; H420-Y424 AromaticContact NE2-CE2 3.79Å; H420-Y424 WeakPolarHBondContact O-CD2 3.2Å; H420-Y424 PolarHBondContact O-N 3.38Å; H420-Y424 VanDerWaalsContact O-N 3.16Å; F421-Y424 CarbonylContact O-C 3.53Å; F421-Y424 PolarHBondContact O-N 2.98Å; K422-Y424 VanDerWaalsContact C-N 3.26Å; K422-Y424 PolarHBondContact O-N 2.95Å; Y424-V426 PolarHBondContact O-N 3.21Å; Y424-V426 VanDerWaalsContact O-N 3.15Å; Y424-V486 WeakPolarHBondContact CE1-O 3.48Å; Y424-V486 WeakPolarHBondContact OH-CA 3.49Å; Y424-F488 WeakPolarHBondContact O-CB 3.39Å; Y424-F488 WeakPolarHBondContact O-CD2 3.44Å; Y424-L491 HydrophobicContact CD2-CD2 4.41Å
425	E	98.3	Very high	98.2	Very high	162 Å²	162	55.4 Å²	55.4	76%	0.757	26%	0.263	S	S	*	.	T	Hydrogen-bonded Turn	trans	56.2	28.1	175	-54.4	-172.8	142.1	0	0	114.8	F421 K422	F421-E425 PolarHBondContact O-N 3.07Å; K422-E425 PolarHBondContact O-N 2.98Å
426	V	98.4	Very high	98.3	Very high	7 Å²	7	51.8 Å²	51.8	4%	0.042	24%	0.241	C	C	.	.			trans	-85.8	116	173.6	176.9	0	0	0	0	109.7	F421 Y424 F431 F488 L491 L495	F421-V426 HydrophobicContact CB-CB 4.43Å; F421-V426 PolarHBondContact O-N 3.43Å; Y424-V426 PolarHBondContact O-N 3.21Å; Y424-V426 VanDerWaalsContact O-N 3.15Å; V426-F431 HydrophobicContact CG1-CD1 4.17Å; V426-F431 HydrophobicContact CG1-CE1 4.1Å; V426-F488 HydrophobicContact CG2-CD2 3.62Å; V426-F488 HydrophobicContact CG2-CE2 4.07Å; V426-L491 HydrophobicContact CB-CD2 4.41Å; V426-L491 HydrophobicContact CG2-CB 4.47Å; V426-L491 HydrophobicContact CG2-CD2 3.75Å; V426-L491 HydrophobicContact CG2-CG 4.05Å; V426-L495 HydrophobicContact CG1-CD1 3.97Å
427	E	98.3	Very high	98.2	Very high	121 Å²	121	47.8 Å²	47.8	57%	0.565	22%	0.22	S	C	*	.			trans	-89.2	140.1	175	-61	178.4	164.3	0	0	110.8	L429 Q430	E427-L429 PolarHBondContact O-N 2.97Å; E427-Q430 HydrophobicContact CB-CG 4.04Å; E427-Q430 WeakPolarHBondContact O-CB 3.26Å; E427-Q430 PolarHBondContact O-N 2.94Å
428	Y	98.5	Very high	98.2	Very high	11 Å²	11	48.3 Å²	48.3	4%	0.043	22%	0.223	C	C	.	.	T	Hydrogen-bonded Turn	trans	-54.2	-32.8	178.3	-75.1	-101.8	0	0	0	113	L406 E407 V410 H418 F421 Q430 F431 A432	L406-Y428 HydrophobicContact CD2-CD1 4.48Å; L406-Y428 HydrophobicContact CG-CD1 4.38Å; E407-Y428 HydrophobicContact CB-CD1 4.18Å; E407-Y428 HydrophobicContact CB-CD2 3.71Å; E407-Y428 HydrophobicContact CB-CE1 4.34Å; E407-Y428 HydrophobicContact CB-CE2 3.93Å; E407-Y428 HydrophobicContact CB-CG 3.87Å; E407-Y428 HydrophobicContact CG-CD2 3.71Å; E407-Y428 HydrophobicContact CG-CE2 3.64Å; E407-Y428 HydrophobicContact CG-CG 4.39Å; V410-Y428 HydrophobicContact CB-CE1 4.13Å; V410-Y428 HydrophobicContact CG1-CE1 4.41Å; V410-Y428 WeakPolarHBondContact CG1-OH 3.43Å; V410-Y428 HydrophobicContact CG2-CE1 4.3Å; H418-Y428 AromaticContact ND1-CE2 3.79Å; H418-Y428 AromaticContact ND1-CZ 3.86Å; H418-Y428 PolarHBondContact ND1-OH 2.76Å; F421-Y428 HydrophobicContact CD2-CD2 4.43Å; F421-Y428 HydrophobicContact CD2-CE1 4.06Å; F421-Y428 AromaticContact CD2-CE2 3.76Å; F421-Y428 HydrophobicContact CD2-CE2 3.76Å; F421-Y428 AromaticContact CD2-CZ 3.55Å; F421-Y428 AromaticContact CE2-CE1 3.92Å; F421-Y428 HydrophobicContact CE2-CE1 3.92Å; F421-Y428 HydrophobicContact CE2-CE2 4.45Å; F421-Y428 AromaticContact CE2-CZ 3.85Å; Y428-Q430 PolarHBondContact O-N 3.39Å; Y428-F431 AromaticContact CD1-CZ 3.82Å; Y428-F431 HydrophobicContact CD1-CZ 3.82Å; Y428-F431 HydrophobicContact CE1-CZ 4.36Å; Y428-F431 HydrophobicContact CG-CZ 4.28Å; Y428-F431 PolarHBondContact O-N 2.99Å; Y428-A432 WeakPolarHBondContact O-CB 3.47Å; Y428-A432 PolarHBondContact O-N 2.67Å
429	L	97.8	Very high	98.2	Very high	86 Å²	86	47.7 Å²	47.7	45%	0.45	22%	0.22	S	C	.	.	H	α-helix	trans	-64.3	-26.3	178.6	-164.8	68.7	0	0	0	113.3	V403 E427 F431 F433	V403-L429 HydrophobicContact CB-CD1 4.43Å; V403-L429 HydrophobicContact CG1-CB 4.3Å; V403-L429 HydrophobicContact CG1-CD1 4.11Å; V403-L429 HydrophobicContact CG2-CD1 4.3Å; E427-L429 PolarHBondContact O-N 2.97Å; L429-F431 VanDerWaalsContact C-N 3.26Å; L429-F431 PolarHBondContact O-N 3.42Å; L429-F433 HydrophobicContact CD1-CB 4.11Å; L429-F433 HydrophobicContact CD1-CD2 4.08Å; L429-F433 VanDerWaalsContact O-CB 3.23Å; L429-F433 WeakPolarHBondContact O-CB 3.31Å
430	Q	98.3	Very high	98.2	Very high	58 Å²	58	43.7 Å²	43.7	27%	0.271	20%	0.199	S	C	.	.	H	α-helix	trans	-70.9	-18.1	-177.1	-63.4	165.3	-1.4	0	0	113.4	E427 Y428 L492 Q496	E427-Q430 HydrophobicContact CB-CG 4.04Å; E427-Q430 WeakPolarHBondContact O-CB 3.26Å; E427-Q430 PolarHBondContact O-N 2.94Å; Y428-Q430 PolarHBondContact O-N 3.39Å; Q430-L492 HydrophobicContact CB-CD1 3.79Å; Q430-L492 HydrophobicContact CB-CD2 4.43Å; Q430-Q496 PolarHBondContact O-NE2 2.92Å
431	F	98.4	Very high	98.1	Very high	4 Å²	4	43.1 Å²	43.1	2%	0.018	20%	0.196	C	C	.	.	H	α-helix	trans	-126.4	-49.4	174.8	64.5	-88.7	0	0	0	112.2	F421 V426 Y428 L429 F433 R434 W435 L475 L492 L495 Q496	F421-F431 HydrophobicContact CD2-CZ 4.47Å; F421-F431 HydrophobicContact CE2-CE1 4.1Å; F421-F431 AromaticContact CE2-CZ 3.73Å; F421-F431 HydrophobicContact CE2-CZ 3.73Å; F421-F431 HydrophobicContact CZ-CE1 4.47Å; F421-F431 HydrophobicContact CZ-CZ 4.18Å; V426-F431 HydrophobicContact CG1-CD1 4.17Å; V426-F431 HydrophobicContact CG1-CE1 4.1Å; Y428-F431 AromaticContact CD1-CZ 3.82Å; Y428-F431 HydrophobicContact CD1-CZ 3.82Å; Y428-F431 HydrophobicContact CE1-CZ 4.36Å; Y428-F431 HydrophobicContact CG-CZ 4.28Å; Y428-F431 PolarHBondContact O-N 2.99Å; L429-F431 VanDerWaalsContact C-N 3.26Å; L429-F431 PolarHBondContact O-N 3.42Å; F431-F433 PolarHBondContact O-N 3.13Å; F431-F433 VanDerWaalsContact O-N 3.17Å; F431-R434 PolarHBondContact O-N 3.35Å; F431-R434 VanDerWaalsContact O-N 3.11Å; F431-W435 HydrophobicContact CD2-CD2 4.14Å; F431-W435 AromaticContact CD2-CE2 3.78Å; F431-W435 HydrophobicContact CD2-CE3 4.32Å; F431-W435 AromaticContact CD2-CH2 3.89Å; F431-W435 HydrophobicContact CD2-CH2 3.89Å; F431-W435 AromaticContact CD2-CZ2 3.66Å; F431-W435 HydrophobicContact CD2-CZ2 3.66Å; F431-W435 HydrophobicContact CD2-CZ3 4.21Å; F431-W435 HydrophobicContact CE2-CE3 4.35Å; F431-W435 AromaticContact CE2-CH2 3.87Å; F431-W435 HydrophobicContact CE2-CH2 3.87Å; F431-W435 HydrophobicContact CE2-CZ2 4.14Å; F431-W435 AromaticContact CE2-CZ3 3.98Å; F431-W435 HydrophobicContact CE2-CZ3 3.98Å; F431-L475 HydrophobicContact CE2-CD1 3.68Å; F431-L475 HydrophobicContact CZ-CD1 3.86Å; F431-L492 HydrophobicContact CB-CD1 4.42Å; F431-L495 HydrophobicContact CB-CB 4.04Å; F431-L495 HydrophobicContact CD1-CB 4.28Å; F431-L495 HydrophobicContact CD1-CD1 3.87Å; F431-L495 HydrophobicContact CD2-CB 4.37Å; F431-L495 HydrophobicContact CE1-CD1 3.91Å; F431-L495 HydrophobicContact CE2-CD2 4.47Å; F431-L495 HydrophobicContact CG-CB 3.98Å; F431-L495 HydrophobicContact CG-CD1 4.37Å; F431-L495 HydrophobicContact CZ-CD1 4.46Å; F431-Q496 HydrophobicContact CB-CG 4.26Å
432	A	98.4	Very high	97.9	Very high	0 Å²	0	45.6 Å²	45.6	0%	0	21%	0.206	C	C	.	.	H	α-helix	trans	-70.3	-15.6	-172.4	0	0	0	0	0	114	V403 L406 Y428 R434 W435 M436	V403-A432 HydrophobicContact CG1-CB 4.46Å; V403-A432 HydrophobicContact CG2-CB 4.13Å; L406-A432 HydrophobicContact CD2-CB 3.72Å; Y428-A432 WeakPolarHBondContact O-CB 3.47Å; Y428-A432 PolarHBondContact O-N 2.67Å; A432-R434 VanDerWaalsContact C-N 3.29Å; A432-R434 PolarHBondContact O-N 3.3Å; A432-W435 HydrophobicContact CB-CE3 4.5Å; A432-W435 PolarHBondContact O-N 2.98Å; A432-M436 VanDerWaalsContact O-CG 3.3Å; A432-M436 WeakPolarHBondContact O-CG 3.31Å; A432-M436 PolarHBondContact O-N 3.5Å
433	F	98.4	Very high	97.8	Very high	73 Å²	73	39.8 Å²	39.8	32%	0.32	18%	0.18	S	C	.	.	H	α-helix	trans	-54.5	-47.7	168.5	178.7	-86.1	0	0	0	110.8	I399 L429 F431 M436 N437	I399-F433 HydrophobicContact CB-CE2 4.43Å; I399-F433 HydrophobicContact CD1-CE2 4.15Å; I399-F433 HydrophobicContact CD1-CZ 4.25Å; I399-F433 HydrophobicContact CG2-CD2 3.48Å; I399-F433 VanDerWaalsContact CG2-CD2 3.48Å; I399-F433 HydrophobicContact CG2-CE2 3.81Å; I399-F433 HydrophobicContact CG2-CG 4.19Å; L429-F433 HydrophobicContact CD1-CB 4.11Å; L429-F433 HydrophobicContact CD1-CD2 4.08Å; L429-F433 VanDerWaalsContact O-CB 3.23Å; L429-F433 WeakPolarHBondContact O-CB 3.31Å; F431-F433 PolarHBondContact O-N 3.13Å; F431-F433 VanDerWaalsContact O-N 3.17Å; F433-M436 PolarHBondContact O-N 2.7Å; F433-N437 HydrophobicContact CD1-CB 4.38Å; F433-N437 HydrophobicContact CE1-CB 4.09Å; F433-N437 WeakPolarHBondContact O-CB 3.39Å; F433-N437 PolarHBondContact O-N 2.99Å
434	R	97.6	Very high	97.7	Very high	44 Å²	44	33.3 Å²	33.3	17%	0.166	15%	0.152	C	C	.	.	H	α-helix	trans	-68	-38.9	179.9	-167.7	176.4	73.2	-165.2	6.2	111.4	I183 F431 A432 M436 N437 N438 R442 E443 Q496	I183-R434 VanDerWaalsContact CD1-NH1 3.28Å; F431-R434 PolarHBondContact O-N 3.35Å; F431-R434 VanDerWaalsContact O-N 3.11Å; A432-R434 VanDerWaalsContact C-N 3.29Å; A432-R434 PolarHBondContact O-N 3.3Å; R434-M436 VanDerWaalsContact C-N 3.32Å; R434-M436 PolarHBondContact O-N 3.48Å; R434-N437 PolarHBondContact O-N 2.93Å; R434-N438 WeakPolarHBondContact O-CB 3.45Å; R434-N438 PolarHBondContact O-N 2.97Å; R434-N438 PolarHBondContact O-OD1 2.82Å; R434-R442 HydrophobicContact CG-CB 4.13Å; R434-R442 HydrophobicContact CG-CG 4.21Å; R434-E443 IonicContact CZ-OE1 3.59Å; R434-E443 VanDerWaalsContact CZ-OE1 3.29Å; R434-E443 IonicContact CZ-OE2 3.82Å; R434-E443 IonicContact NE-OE1 3.71Å; R434-E443 PolarHBondContact NE-OE1 3.23Å; R434-E443 IonicContact NE-OE2 3.9Å; R434-E443 IonicContact NH2-OE1 3.53Å; R434-E443 PolarHBondContact NH2-OE1 3.5Å; R434-E443 IonicContact NH2-OE2 2.74Å; R434-E443 PolarHBondContact NH2-OE2 3.27Å; R434-Q496 PolarHBondContact NH2-O 3.5Å
435	W	98.4	Very high	97.5	Very high	0 Å²	0	31.5 Å²	31.5	0%	0	15%	0.145	C	C	.	.	H	α-helix	trans	-58.2	-45.7	177.2	-61.6	7.5	0	0	0	111.1	L406 F431 A432 L439 L440 E443 H467 C471 F474 L475 L498	L406-W435 HydrophobicContact CD2-CE3 4.48Å; F431-W435 HydrophobicContact CD2-CD2 4.14Å; F431-W435 AromaticContact CD2-CE2 3.78Å; F431-W435 HydrophobicContact CD2-CE3 4.32Å; F431-W435 AromaticContact CD2-CH2 3.89Å; F431-W435 HydrophobicContact CD2-CH2 3.89Å; F431-W435 AromaticContact CD2-CZ2 3.66Å; F431-W435 HydrophobicContact CD2-CZ2 3.66Å; F431-W435 HydrophobicContact CD2-CZ3 4.21Å; F431-W435 HydrophobicContact CE2-CE3 4.35Å; F431-W435 AromaticContact CE2-CH2 3.87Å; F431-W435 HydrophobicContact CE2-CH2 3.87Å; F431-W435 HydrophobicContact CE2-CZ2 4.14Å; F431-W435 AromaticContact CE2-CZ3 3.98Å; F431-W435 HydrophobicContact CE2-CZ3 3.98Å; A432-W435 HydrophobicContact CB-CE3 4.5Å; A432-W435 PolarHBondContact O-N 2.98Å; W435-L439 CarbonylContact O-C 3.49Å; W435-L439 VanDerWaalsContact O-CA 3.24Å; W435-L439 WeakPolarHBondContact O-CA 3.42Å; W435-L439 PolarHBondContact O-N 3.05Å; W435-L440 HydrophobicContact CB-CD2 3.69Å; W435-L440 HydrophobicContact CB-CG 4.4Å; W435-L440 HydrophobicContact CD2-CD2 3.72Å; W435-L440 HydrophobicContact CE3-CD2 4.01Å; W435-L440 HydrophobicContact CG-CD2 3.6Å; W435-L440 PolarHBondContact O-N 3.43Å; W435-E443 VanDerWaalsContact CD1-CG 3.46Å; W435-E443 HydrophobicContact CG-CG 4.18Å; W435-E443 PolarHBondContact NE1-OE2 3.44Å; W435-E443 VanDerWaalsContact NE1-OE2 3.16Å; W435-H467 PolarHBondContact O-NE2 3.49Å; W435-C471 HydrophobicContact CE3-CB 4.19Å; W435-F474 HydrophobicContact CE3-CD1 4.46Å; W435-F474 AromaticContact CH2-CD1 3.95Å; W435-F474 HydrophobicContact CH2-CD1 3.95Å; W435-F474 HydrophobicContact CH2-CE1 4.37Å; W435-F474 HydrophobicContact CZ2-CD1 4.2Å; W435-F474 HydrophobicContact CZ2-CE1 4.17Å; W435-F474 HydrophobicContact CZ3-CD1 4.08Å; W435-L475 HydrophobicContact CH2-CB 4.18Å; W435-L475 HydrophobicContact CH2-CD1 4.06Å; W435-L475 HydrophobicContact CH2-CG 4.2Å; W435-L475 HydrophobicContact CZ3-CB 4.12Å; W435-L475 HydrophobicContact CZ3-CD1 4Å; W435-L475 HydrophobicContact CZ3-CG 4.41Å; W435-L498 HydrophobicContact CH2-CD1 4.1Å; W435-L498 HydrophobicContact CZ2-CD1 3.72Å
436	M	98.2	Very high	97.2	Very high	1 Å²	1	24.2 Å²	24.2	1%	0.005	11%	0.111	C	C	.	.	H	α-helix	trans	-78.4	-34.6	179.7	-62.1	-65.6	173.7	0	0	113.7	N391 I399 K402 V403 L406 A432 F433 R434 H467 L468 C471	N391-M436 PolarHBondContact ND2-O 3.02Å; I399-M436 HydrophobicContact CG2-CB 4.06Å; K402-M436 HydrophobicContact CB-CE 4.26Å; K402-M436 HydrophobicContact CB-CG 4.08Å; K402-M436 HydrophobicContact CB-SD 3.73Å; V403-M436 HydrophobicContact CG2-CG 4.07Å; L406-M436 HydrophobicContact CB-CE 4.16Å; L406-M436 HydrophobicContact CD2-CE 4.1Å; A432-M436 VanDerWaalsContact O-CG 3.3Å; A432-M436 WeakPolarHBondContact O-CG 3.31Å; A432-M436 PolarHBondContact O-N 3.5Å; F433-M436 PolarHBondContact O-N 2.7Å; R434-M436 VanDerWaalsContact C-N 3.32Å; R434-M436 PolarHBondContact O-N 3.48Å; M436-H467 VanDerWaalsContact SD-CD2 3.58Å; M436-L468 HydrophobicContact CE-CD1 4Å; M436-C471 HydrophobicContact CE-CB 3.92Å
437	N	97.6	Very high	97	Very high	7 Å²	7	24.8 Å²	24.8	4%	0.037	11%	0.113	C	C	.	.	H	α-helix	trans	-70.6	-34.5	179.1	-171.9	73.3	0	0	0	112.3	Q335 Y392 Q396 I399 F433 R434	Q335-N437 PolarHBondContact O-ND2 2.99Å; Y392-N437 PolarHBondContact OH-O 3.34Å; Q396-N437 PolarHBondContact NE2-OD1 3.46Å; I399-N437 HydrophobicContact CD1-CB 3.71Å; I399-N437 WeakPolarHBondContact CD1-OD1 3.21Å; F433-N437 HydrophobicContact CD1-CB 4.38Å; F433-N437 HydrophobicContact CE1-CB 4.09Å; F433-N437 WeakPolarHBondContact O-CB 3.39Å; F433-N437 PolarHBondContact O-N 2.99Å; R434-N437 PolarHBondContact O-N 2.93Å
438	N	97.4	Very high	96.9	Very high	11 Å²	11	19 Å²	19	6%	0.059	9%	0.086	C	C	.	.	T	Hydrogen-bonded Turn	trans	-118.1	15.2	-173.2	-55.2	79.4	0	0	0	112.6	G336 D339 R434 L440 M441 R442	G336-N438 WeakPolarHBondContact CA-ND2 3.48Å; D339-N438 PolarHBondContact OD2-ND2 3.21Å; R434-N438 WeakPolarHBondContact O-CB 3.45Å; R434-N438 PolarHBondContact O-N 2.97Å; R434-N438 PolarHBondContact O-OD1 2.82Å; N438-L440 VanDerWaalsContact C-N 3.34Å; N438-L440 PolarHBondContact O-N 3.34Å; N438-M441 WeakPolarHBondContact O-CB 3.33Å; N438-M441 WeakPolarHBondContact O-CG 3.31Å; N438-M441 PolarHBondContact O-N 3.35Å; N438-R442 HydrophobicContact CB-CG 4.1Å
439	L	98	Very high	96.9	Very high	2 Å²	2	18.5 Å²	18.5	1%	0.01	8%	0.084	C	C	.	.	T	Hydrogen-bonded Turn	trans	45.4	50.1	179.3	-56.4	-178.7	0	0	0	114.4	L340 L384 I388 W435 M441 W453 F463	L340-L439 HydrophobicContact CD2-CB 4.4Å; L340-L439 HydrophobicContact CD2-CD1 4.07Å; L340-L439 HydrophobicContact CD2-CG 4.15Å; L384-L439 HydrophobicContact CD1-CD1 4.42Å; L384-L439 HydrophobicContact CD2-CD1 4Å; L384-L439 HydrophobicContact CG-CD1 4.42Å; I388-L439 HydrophobicContact CD1-CD1 4.2Å; I388-L439 HydrophobicContact CD1-CD2 4.38Å; W435-L439 CarbonylContact O-C 3.49Å; W435-L439 VanDerWaalsContact O-CA 3.24Å; W435-L439 WeakPolarHBondContact O-CA 3.42Å; W435-L439 PolarHBondContact O-N 3.05Å; L439-M441 PolarHBondContact O-N 2.98Å; L439-M441 VanDerWaalsContact O-N 3.1Å; L439-W453 HydrophobicContact CB-CZ2 4.21Å; L439-W453 HydrophobicContact CD1-CZ2 3.92Å; L439-F463 HydrophobicContact CD1-CE2 3.77Å; L439-F463 HydrophobicContact CD1-CZ 4.48Å; L439-F463 HydrophobicContact CD2-CE2 4.12Å
440	L	98.1	Very high	96.8	Very high	0 Å²	0	15 Å²	15	0%	0	7%	0.065	C	C	.	.	T	Hydrogen-bonded Turn	trans	58.9	6	-174.3	-69	167.3	0	0	0	116.5	W435 N438 R442 E443 L444 V470 F474	W435-L440 HydrophobicContact CB-CD2 3.69Å; W435-L440 HydrophobicContact CB-CG 4.4Å; W435-L440 HydrophobicContact CD2-CD2 3.72Å; W435-L440 HydrophobicContact CE3-CD2 4.01Å; W435-L440 HydrophobicContact CG-CD2 3.6Å; W435-L440 PolarHBondContact O-N 3.43Å; N438-L440 VanDerWaalsContact C-N 3.34Å; N438-L440 PolarHBondContact O-N 3.34Å; L440-R442 PolarHBondContact O-N 3.07Å; L440-R442 VanDerWaalsContact O-N 3.1Å; L440-E443 HydrophobicContact CB-CG 4.41Å; L440-E443 HydrophobicContact CD2-CB 4.23Å; L440-E443 HydrophobicContact CD2-CG 3.64Å; L440-E443 WeakPolarHBondContact O-CA 3.46Å; L440-E443 PolarHBondContact O-N 2.66Å; L440-L444 HydrophobicContact CB-CD1 3.97Å; L440-L444 PolarHBondContact O-N 2.69Å; L440-V470 HydrophobicContact CD1-CG1 3.82Å; L440-F474 HydrophobicContact CD1-CD1 4.46Å; L440-F474 HydrophobicContact CD2-CD1 3.69Å; L440-F474 HydrophobicContact CD2-CE1 3.84Å
441	M	95.8	Very high	96.8	Very high	14 Å²	14	13 Å²	13	7%	0.069	6%	0.055	C	C	.	.	T	Hydrogen-bonded Turn	trans	-64.8	-16.2	-177.4	-65.5	-173.6	58.9	0	0	115.6	D339 L340 T342 P343 N438 L439 L446 T449 W453	D339-M441 HydrophobicContact CB-CE 4.22Å; D339-M441 HydrophobicContact CB-SD 4.38Å; D339-M441 WeakPolarHBondContact O-CE 3.32Å; L340-M441 HydrophobicContact CD2-SD 3.88Å; T342-M441 WeakPolarHBondContact OG1-CE 3.19Å; P343-M441 HydrophobicContact CG-CE 3.52Å; P343-M441 HydrophobicContact CG-SD 3.97Å; N438-M441 WeakPolarHBondContact O-CB 3.33Å; N438-M441 WeakPolarHBondContact O-CG 3.31Å; N438-M441 PolarHBondContact O-N 3.35Å; L439-M441 PolarHBondContact O-N 2.98Å; L439-M441 VanDerWaalsContact O-N 3.1Å; M441-L446 HydrophobicContact CE-CD1 3.89Å; M441-T449 HydrophobicContact CE-CG2 4.03Å; M441-T449 HydrophobicContact CG-CG2 3.55Å; M441-T449 HydrophobicContact SD-CG2 3.95Å; M441-W453 HydrophobicContact CG-CZ2 4.17Å; M441-W453 HydrophobicContact SD-CH2 3.78Å; M441-W453 HydrophobicContact SD-CZ2 3.46Å; M441-W453 WeakPolarHBondContact SD-CZ2 3.41Å
442	R	95.3	Very high	96.8	Very high	54 Å²	54	12.8 Å²	12.8	20%	0.204	6%	0.055	C	C	.	.	T	Hydrogen-bonded Turn	trans	-91.2	-5	173.8	-62.8	-58.6	-170.1	144.6	-2.1	112.8	D339 R434 N438 L440	D339-R442 IonicContact OD1-CZ 3.01Å; D339-R442 IonicContact OD1-NE 2.74Å; D339-R442 PolarHBondContact OD1-NE 3.27Å; D339-R442 IonicContact OD1-NH2 3.88Å; D339-R442 PolarHBondContact OD1-NH2 3Å; D339-R442 IonicContact OD2-CZ 2.69Å; D339-R442 VanDerWaalsContact OD2-CZ 3.26Å; D339-R442 IonicContact OD2-NE 2.67Å; D339-R442 PolarHBondContact OD2-NE 3.26Å; D339-R442 IonicContact OD2-NH2 3.29Å; D339-R442 PolarHBondContact OD2-NH2 3.42Å; R434-R442 HydrophobicContact CG-CB 4.13Å; R434-R442 HydrophobicContact CG-CG 4.21Å; N438-R442 HydrophobicContact CB-CG 4.1Å; L440-R442 PolarHBondContact O-N 3.07Å; L440-R442 VanDerWaalsContact O-N 3.1Å
443	E	96.3	Very high	96.8	Very high	3 Å²	3	12.9 Å²	12.9	1%	0.014	6%	0.055	C	C	.	.	T	Hydrogen-bonded Turn	trans	-114.8	-7.1	-177.7	-27	-56.5	134.3	0	0	112.9	R434 W435 L440 F474 T500	R434-E443 IonicContact CZ-OE1 3.59Å; R434-E443 VanDerWaalsContact CZ-OE1 3.29Å; R434-E443 IonicContact CZ-OE2 3.82Å; R434-E443 IonicContact NE-OE1 3.71Å; R434-E443 PolarHBondContact NE-OE1 3.23Å; R434-E443 IonicContact NE-OE2 3.9Å; R434-E443 IonicContact NH2-OE1 3.53Å; R434-E443 PolarHBondContact NH2-OE1 3.5Å; R434-E443 IonicContact NH2-OE2 2.74Å; R434-E443 PolarHBondContact NH2-OE2 3.27Å; W435-E443 VanDerWaalsContact CD1-CG 3.46Å; W435-E443 HydrophobicContact CG-CG 4.18Å; W435-E443 PolarHBondContact NE1-OE2 3.44Å; W435-E443 VanDerWaalsContact NE1-OE2 3.16Å; L440-E443 HydrophobicContact CB-CG 4.41Å; L440-E443 HydrophobicContact CD2-CB 4.23Å; L440-E443 HydrophobicContact CD2-CG 3.64Å; L440-E443 WeakPolarHBondContact O-CA 3.46Å; L440-E443 PolarHBondContact O-N 2.66Å; E443-F474 HydrophobicContact CB-CE1 3.71Å; E443-F474 HydrophobicContact CB-CZ 3.82Å; E443-F474 HydrophobicContact CG-CE1 4.23Å; E443-T500 WeakPolarHBondContact O-CB 3.26Å; E443-T500 VanDerWaalsContact O-CG2 3.27Å; E443-T500 WeakPolarHBondContact O-CG2 3.33Å; E443-T500 PolarHBondContact O-OG1 2.97Å
444	L	95.9	Very high	96.8	Very high	4 Å²	4	9.4 Å²	9.4	2%	0.021	4%	0.04	C	C	.	.	S	Bend	trans	-136.4	148.1	-172.3	-71.1	173.9	0	0	0	111.4	V187 L440 C448 L452 F474 T500 W503	V187-L444 VanDerWaalsContact CG1-C 3.41Å; L440-L444 HydrophobicContact CB-CD1 3.97Å; L440-L444 PolarHBondContact O-N 2.69Å; L444-C448 HydrophobicContact CB-CB 4.16Å; L444-C448 HydrophobicContact CD2-CB 4.45Å; L444-L452 HydrophobicContact CD1-CD2 3.9Å; L444-F474 HydrophobicContact CD2-CE2 4.01Å; L444-F474 HydrophobicContact CD2-CZ 4.37Å; L444-T500 HydrophobicContact CD2-CG2 4.05Å; L444-W503 HydrophobicContact CD2-CE3 3.66Å; L444-W503 HydrophobicContact CD2-CZ3 3.9Å
445	P	94.2	Very high	96.8	Very high	0 Å²	0	7.3 Å²	7.3	0%	0	3%	0.032	C	C	.	.			trans	-60.6	154.2	172.3	-22.6	30.7	0	0	0	112.4	V187 R447 C448 T449 T500	V187-P445 HydrophobicContact CG1-CB 4.3Å; V187-P445 VanDerWaalsContact CG1-CD 3.43Å; V187-P445 HydrophobicContact CG1-CG 3.69Å; V187-P445 VanDerWaalsContact CG1-N 3.3Å; V187-P445 WeakPolarHBondContact O-CA 3.33Å; P445-R447 VanDerWaalsContact C-N 3.27Å; P445-R447 HydrophobicContact CB-CG 3.81Å; P445-R447 PolarHBondContact O-N 3.44Å; P445-C448 HydrophobicContact CB-CB 4.3Å; P445-C448 HydrophobicContact CG-CB 4.39Å; P445-C448 CarbonylContact O-C 3.26Å; P445-C448 WeakPolarHBondContact O-CA 3.33Å; P445-C448 VanDerWaalsContact O-CB 3.32Å; P445-C448 WeakPolarHBondContact O-CB 3.38Å; P445-C448 PolarHBondContact O-N 2.87Å; P445-T449 PolarHBondContact O-N 3.31Å; P445-T449 PolarHBondContact O-OG1 3.36Å; P445-T500 WeakPolarHBondContact CG-O 3.29Å
446	L	92.7	Very high	96.8	Very high	8 Å²	8	7.6 Å²	7.6	4%	0.042	3%	0.033	C	C	.	.	H	α-helix	trans	-64.5	-33.4	-177.2	-167.1	65.3	0	0	0	111.8	R189 I190 F308 P343 V346 M441 C448 T449 I450	R189-L446 PolarHBondContact O-N 3.46Å; I190-L446 HydrophobicContact CD1-CD2 3.81Å; I190-L446 HydrophobicContact CG1-CB 4.33Å; I190-L446 HydrophobicContact CG1-CD2 3.78Å; F308-L446 HydrophobicContact CE2-CD2 4.43Å; F308-L446 HydrophobicContact CZ-CD2 4.17Å; P343-L446 HydrophobicContact CB-CD1 4.46Å; P343-L446 HydrophobicContact CG-CD1 3.97Å; V346-L446 HydrophobicContact CB-CD2 4.37Å; V346-L446 HydrophobicContact CG1-CD2 4.44Å; V346-L446 HydrophobicContact CG2-CD2 3.88Å; M441-L446 HydrophobicContact CE-CD1 3.89Å; L446-C448 VanDerWaalsContact C-N 3.31Å; L446-C448 PolarHBondContact O-N 3.13Å; L446-T449 HydrophobicContact CD1-CG2 4.45Å; L446-T449 WeakPolarHBondContact O-CB 3.48Å; L446-T449 PolarHBondContact O-N 2.86Å; L446-I450 HydrophobicContact CG-CD1 4.18Å; L446-I450 WeakPolarHBondContact O-CB 3.37Å; L446-I450 VanDerWaalsContact O-CG1 3.27Å; L446-I450 WeakPolarHBondContact O-CG1 3.4Å; L446-I450 PolarHBondContact O-N 2.95Å
447	R	93	Very high	96.6	Very high	19 Å²	19	8.6 Å²	8.6	7%	0.072	4%	0.038	C	C	.	.	H	α-helix	trans	-55.5	-43.9	167.3	50.9	171.3	-169.6	-78.4	-12.5	112.8	I190 S191 D192 P445 I450 R451 I501 W503	I190-R447 WeakPolarHBondContact O-CB 3.13Å; S191-R447 PolarHBondContact O-NH1 3.02Å; D192-R447 WeakPolarHBondContact OD1-CD 3.41Å; D192-R447 IonicContact OD1-NE 2.68Å; P445-R447 VanDerWaalsContact C-N 3.27Å; P445-R447 HydrophobicContact CB-CG 3.81Å; P445-R447 PolarHBondContact O-N 3.44Å; R447-I450 PolarHBondContact O-N 3.01Å; R447-R451 WeakPolarHBondContact O-CB 3.32Å; R447-R451 PolarHBondContact O-N 2.86Å; R447-I501 PolarHBondContact NH2-O 3.31Å; R447-W503 VanDerWaalsContact CZ-O 3.23Å; R447-W503 PolarHBondContact NE-O 2.7Å; R447-W503 PolarHBondContact NH2-O 3.18Å
448	C	96.9	Very high	96.5	Very high	0 Å²	0	8.5 Å²	8.5	0%	0	4%	0.037	C	C	.	.	H	α-helix	trans	-71.1	-37.8	179.8	-63.9	0	0	0	0	111.5	L444 P445 L446 R451 L452 W503 G504 V508	L444-C448 HydrophobicContact CB-CB 4.16Å; L444-C448 HydrophobicContact CD2-CB 4.45Å; P445-C448 HydrophobicContact CB-CB 4.3Å; P445-C448 HydrophobicContact CG-CB 4.39Å; P445-C448 CarbonylContact O-C 3.26Å; P445-C448 WeakPolarHBondContact O-CA 3.33Å; P445-C448 VanDerWaalsContact O-CB 3.32Å; P445-C448 WeakPolarHBondContact O-CB 3.38Å; P445-C448 PolarHBondContact O-N 2.87Å; L446-C448 VanDerWaalsContact C-N 3.31Å; L446-C448 PolarHBondContact O-N 3.13Å; C448-R451 PolarHBondContact O-N 3.2Å; C448-L452 WeakPolarHBondContact O-CB 3.43Å; C448-L452 PolarHBondContact O-N 2.93Å; C448-W503 VanDerWaalsContact SG-C 3.52Å; C448-W503 PolarHBondContact SG-O 3.21Å; C448-G504 PolarHBondContact SG-O 3.38Å; C448-V508 HydrophobicContact CB-CG2 3.55Å
449	T	97.6	Very high	96.2	Very high	1 Å²	1	8.9 Å²	8.9	1%	0.006	4%	0.039	C	C	.	.	H	α-helix	trans	-58.6	-49.4	168.5	-61.3	0	0	0	0	111.3	P343 M441 P445 L446 R451 L452 W453	P343-T449 HydrophobicContact CB-CG2 4.36Å; P343-T449 HydrophobicContact CG-CG2 3.75Å; M441-T449 HydrophobicContact CE-CG2 4.03Å; M441-T449 HydrophobicContact CG-CG2 3.55Å; M441-T449 HydrophobicContact SD-CG2 3.95Å; P445-T449 PolarHBondContact O-N 3.31Å; P445-T449 PolarHBondContact O-OG1 3.36Å; L446-T449 HydrophobicContact CD1-CG2 4.45Å; L446-T449 WeakPolarHBondContact O-CB 3.48Å; L446-T449 PolarHBondContact O-N 2.86Å; T449-R451 PolarHBondContact O-N 3.09Å; T449-L452 WeakPolarHBondContact O-CB 3.32Å; T449-L452 PolarHBondContact O-N 3.25Å; T449-W453 HydrophobicContact CG2-CD2 4.08Å; T449-W453 HydrophobicContact CG2-CG 4.22Å; T449-W453 HydrophobicContact CG2-CZ2 4.21Å; T449-W453 WeakPolarHBondContact O-CB 3.34Å; T449-W453 VanDerWaalsContact O-CG 3.31Å; T449-W453 PolarHBondContact O-N 3.18Å
450	I	97.3	Very high	95.4	Very high	11 Å²	11	12.1 Å²	12.1	6%	0.056	7%	0.066	C	C	.	.	H	α-helix	trans	-60.4	-47.7	179.6	-71	165.3	0	0	0	110.1	R242 W246 P343 V346 V347 L446 R447 L452 W453 D454	R242-I450 VanDerWaalsContact CD-CG2 3.45Å; W246-I450 HydrophobicContact CH2-CB 4.45Å; W246-I450 HydrophobicContact CH2-CG1 4.25Å; W246-I450 HydrophobicContact CH2-CG2 4.22Å; W246-I450 HydrophobicContact CZ2-CB 4.47Å; W246-I450 HydrophobicContact CZ2-CG2 3.92Å; P343-I450 HydrophobicContact CB-CG1 3.97Å; V346-I450 HydrophobicContact CB-CD1 4.48Å; V346-I450 HydrophobicContact CG1-CD1 3.85Å; V347-I450 HydrophobicContact CG2-CD1 4.13Å; V347-I450 HydrophobicContact CG2-CG1 4.14Å; V347-I450 HydrophobicContact CG2-CG2 3.81Å; L446-I450 HydrophobicContact CG-CD1 4.18Å; L446-I450 WeakPolarHBondContact O-CB 3.37Å; L446-I450 VanDerWaalsContact O-CG1 3.27Å; L446-I450 WeakPolarHBondContact O-CG1 3.4Å; L446-I450 PolarHBondContact O-N 2.95Å; R447-I450 PolarHBondContact O-N 3.01Å; I450-L452 VanDerWaalsContact C-N 3.34Å; I450-L452 PolarHBondContact O-N 3.27Å; I450-W453 PolarHBondContact O-N 3.01Å; I450-W453 VanDerWaalsContact O-N 3.16Å; I450-D454 PolarHBondContact O-N 2.62Å
451	R	97.8	Very high	94.5	Very high	17 Å²	17	18.7 Å²	18.7	6%	0.064	10%	0.097	C	C	.	.	H	α-helix	trans	-60.2	-40.6	174.6	173.1	59.3	-168.2	85.4	3.1	112.4	S235 R447 C448 T449 W453 D454 T455 N505 V508	S235-R451 VanDerWaalsContact C-NH2 3.32Å; S235-R451 PolarHBondContact O-NH2 2.94Å; R447-R451 WeakPolarHBondContact O-CB 3.32Å; R447-R451 PolarHBondContact O-N 2.86Å; C448-R451 PolarHBondContact O-N 3.2Å; T449-R451 PolarHBondContact O-N 3.09Å; R451-W453 VanDerWaalsContact C-N 3.31Å; R451-D454 WeakPolarHBondContact O-CB 3.45Å; R451-T455 PolarHBondContact NH1-OG1 2.87Å; R451-N505 WeakPolarHBondContact CB-OD1 3.37Å; R451-N505 WeakPolarHBondContact CG-OD1 3.4Å; R451-V508 HydrophobicContact CB-CG1 4.28Å; R451-V508 HydrophobicContact CG-CB 4.01Å; R451-V508 HydrophobicContact CG-CG1 3.72Å
452	L	98.3	Very high	93.7	Very high	0 Å²	0	19.5 Å²	19.5	0%	0	11%	0.108	C	C	.	.	H	α-helix	trans	-64.6	-37.7	176.1	179	60.2	0	0	0	111.5	L444 C448 T449 I450 T455 Y456 V470 V508 L512	L444-L452 HydrophobicContact CD1-CD2 3.9Å; C448-L452 WeakPolarHBondContact O-CB 3.43Å; C448-L452 PolarHBondContact O-N 2.93Å; T449-L452 WeakPolarHBondContact O-CB 3.32Å; T449-L452 PolarHBondContact O-N 3.25Å; I450-L452 VanDerWaalsContact C-N 3.34Å; I450-L452 PolarHBondContact O-N 3.27Å; L452-T455 PolarHBondContact O-N 3.37Å; L452-Y456 HydrophobicContact CD1-CD1 4.38Å; L452-Y456 HydrophobicContact CD1-CE1 3.73Å; L452-Y456 HydrophobicContact CD1-CE2 4.38Å; L452-Y456 HydrophobicContact CD2-CE2 4.03Å; L452-Y456 HydrophobicContact CG-CD2 4.38Å; L452-Y456 HydrophobicContact CG-CE1 4.1Å; L452-Y456 HydrophobicContact CG-CE2 3.85Å; L452-Y456 PolarHBondContact O-N 3.18Å; L452-V470 HydrophobicContact CD1-CG1 4.13Å; L452-V470 HydrophobicContact CD1-CG2 4.49Å; L452-V508 HydrophobicContact CB-CG1 4.01Å; L452-V508 HydrophobicContact CD1-CG1 4.49Å; L452-L512 HydrophobicContact CD1-CD1 4.43Å; L452-L512 HydrophobicContact CD1-CD2 3.71Å; L452-L512 HydrophobicContact CD1-CG 4.11Å
453	W	98.1	Very high	93.6	Very high	2 Å²	2	17.8 Å²	17.8	1%	0.008	10%	0.103	C	C	.	.	H	α-helix	trans	-79.1	-19.1	-178.1	-73.9	25	0	0	0	114	W246 L340 P343 F344 L384 L439 M441 T449 I450 R451 T455 Y456 Q457	W246-W453 HydrophobicContact CH2-CB 3.89Å; W246-W453 HydrophobicContact CH2-CE3 4.2Å; W246-W453 HydrophobicContact CZ2-CB 3.82Å; W246-W453 HydrophobicContact CZ3-CE3 4.42Å; L340-W453 HydrophobicContact CB-CH2 4.21Å; L340-W453 HydrophobicContact CD2-CH2 3.85Å; L340-W453 HydrophobicContact CD2-CZ2 3.88Å; P343-W453 HydrophobicContact CB-CD2 4.46Å; P343-W453 HydrophobicContact CB-CE3 3.78Å; P343-W453 HydrophobicContact CB-CZ3 3.81Å; P343-W453 HydrophobicContact CG-CD2 4.37Å; P343-W453 HydrophobicContact CG-CE3 3.85Å; P343-W453 HydrophobicContact CG-CH2 3.73Å; P343-W453 HydrophobicContact CG-CZ2 4.25Å; P343-W453 HydrophobicContact CG-CZ3 3.5Å; P343-W453 VanDerWaalsContact CG-CZ3 3.5Å; F344-W453 HydrophobicContact CD2-CZ3 4.03Å; F344-W453 HydrophobicContact CE2-CE3 4.19Å; F344-W453 HydrophobicContact CE2-CH2 4.4Å; F344-W453 AromaticContact CE2-CZ3 3.49Å; F344-W453 HydrophobicContact CE2-CZ3 3.49Å; F344-W453 VanDerWaalsContact CE2-CZ3 3.49Å; F344-W453 HydrophobicContact CZ-CE3 4.08Å; F344-W453 AromaticContact CZ-CZ3 3.84Å; F344-W453 HydrophobicContact CZ-CZ3 3.84Å; L384-W453 HydrophobicContact CD2-CE3 4.38Å; L384-W453 HydrophobicContact CD2-CH2 3.42Å; L384-W453 VanDerWaalsContact CD2-CH2 3.42Å; L384-W453 HydrophobicContact CD2-CZ2 4.02Å; L384-W453 HydrophobicContact CD2-CZ3 3.65Å; L439-W453 HydrophobicContact CB-CZ2 4.21Å; L439-W453 HydrophobicContact CD1-CZ2 3.92Å; M441-W453 HydrophobicContact CG-CZ2 4.17Å; M441-W453 HydrophobicContact SD-CH2 3.78Å; M441-W453 HydrophobicContact SD-CZ2 3.46Å; M441-W453 WeakPolarHBondContact SD-CZ2 3.41Å; T449-W453 HydrophobicContact CG2-CD2 4.08Å; T449-W453 HydrophobicContact CG2-CG 4.22Å; T449-W453 HydrophobicContact CG2-CZ2 4.21Å; T449-W453 WeakPolarHBondContact O-CB 3.34Å; T449-W453 VanDerWaalsContact O-CG 3.31Å; T449-W453 PolarHBondContact O-N 3.18Å; I450-W453 PolarHBondContact O-N 3.01Å; I450-W453 VanDerWaalsContact O-N 3.16Å; R451-W453 VanDerWaalsContact C-N 3.31Å; W453-T455 PolarHBondContact O-N 3.12Å; W453-Y456 AromaticContact CD1-CD2 3.61Å; W453-Y456 HydrophobicContact CG-CD2 4.38Å; W453-Y456 AromaticContact NE1-CD2 3.96Å; W453-Q457 PolarHBondContact O-N 2.88Å; W453-Q457 VanDerWaalsContact O-N 3.12Å; W453-Q457 PolarHBondContact O-NE2 3.31Å
454	D	98	Very high	93.3	Very high	0 Å²	0	19.2 Å²	19.2	0%	0	11%	0.113	C	C	.	.	H	α-helix	trans	-54.8	-45.7	162	-69.6	-19.8	0	0	0	109.9	I237 R242 W246 I450 R451 A458	I237-D454 HydrophobicContact CB-CB 4.44Å; I237-D454 HydrophobicContact CD1-CB 3.86Å; I237-D454 WeakPolarHBondContact CD1-OD1 3.4Å; I237-D454 HydrophobicContact CG1-CB 3.95Å; I237-D454 PolarHBondContact N-OD2 3.36Å; R242-D454 WeakPolarHBondContact CD-OD1 3.27Å; R242-D454 WeakPolarHBondContact CG-OD1 3.33Å; R242-D454 IonicContact CZ-OD2 2.78Å; R242-D454 IonicContact NE-OD1 2.72Å; R242-D454 PolarHBondContact NE-OD1 2.71Å; R242-D454 IonicContact NE-OD2 3.32Å; R242-D454 PolarHBondContact NE-OD2 3.15Å; R242-D454 IonicContact NH2-OD2 3.83Å; W246-D454 PolarHBondContact NE1-OD1 2.81Å; I450-D454 PolarHBondContact O-N 2.62Å; R451-D454 WeakPolarHBondContact O-CB 3.45Å; D454-A458 PolarHBondContact O-N 3.08Å
455	T	97.9	Very high	93.1	Very high	0 Å²	0	22.9 Å²	22.9	0%	0	13%	0.13	C	C	.	.	H	α-helix	trans	-76.5	-38	-179.7	-51.7	0	0	0	0	112.7	W234 R451 L452 W453 Q457 A458 E459 F466 L512	W234-T455 HydrophobicContact CD2-CG2 3.66Å; W234-T455 VanDerWaalsContact CE2-CG2 3.49Å; W234-T455 HydrophobicContact CE3-CG2 4.34Å; W234-T455 HydrophobicContact CG-CG2 3.79Å; W234-T455 HydrophobicContact CZ2-CG2 4.01Å; W234-T455 WeakPolarHBondContact O-CG2 3.46Å; W234-T455 PolarHBondContact O-OG1 2.87Å; R451-T455 PolarHBondContact NH1-OG1 2.87Å; L452-T455 PolarHBondContact O-N 3.37Å; W453-T455 PolarHBondContact O-N 3.12Å; T455-Q457 VanDerWaalsContact C-N 3.29Å; T455-Q457 PolarHBondContact O-N 2.94Å; T455-A458 WeakPolarHBondContact O-CA 3.48Å; T455-A458 WeakPolarHBondContact O-CB 3.48Å; T455-A458 PolarHBondContact O-N 2.86Å; T455-E459 PolarHBondContact O-N 3.21Å; T455-F466 HydrophobicContact CG2-CE1 4.04Å; T455-L512 HydrophobicContact CG2-CD1 4.1Å; T455-L512 HydrophobicContact CG2-CD2 3.79Å; T455-L512 WeakPolarHBondContact OG1-CD1 3.43Å
456	Y	97.6	Very high	93.2	Very high	5 Å²	5	23 Å²	23	2%	0.02	13%	0.13	C	C	.	.	H	α-helix	trans	-62.5	-33.4	175.7	-71.8	-7.6	0	0	0	113.4	L452 W453 F463 F466 H467 V470	L452-Y456 HydrophobicContact CD1-CD1 4.38Å; L452-Y456 HydrophobicContact CD1-CE1 3.73Å; L452-Y456 HydrophobicContact CD1-CE2 4.38Å; L452-Y456 HydrophobicContact CD2-CE2 4.03Å; L452-Y456 HydrophobicContact CG-CD2 4.38Å; L452-Y456 HydrophobicContact CG-CE1 4.1Å; L452-Y456 HydrophobicContact CG-CE2 3.85Å; L452-Y456 PolarHBondContact O-N 3.18Å; W453-Y456 AromaticContact CD1-CD2 3.61Å; W453-Y456 HydrophobicContact CG-CD2 4.38Å; W453-Y456 AromaticContact NE1-CD2 3.96Å; Y456-F463 HydrophobicContact CD1-CB 4Å; Y456-F463 HydrophobicContact CD2-CB 4.28Å; Y456-F463 HydrophobicContact CD2-CD2 4.13Å; Y456-F463 HydrophobicContact CD2-CG 4.49Å; Y456-F463 HydrophobicContact CG-CB 3.7Å; Y456-F463 HydrophobicContact CG-CD2 4.4Å; Y456-F463 HydrophobicContact CG-CG 4.33Å; Y456-F466 HydrophobicContact CD1-CD1 4.1Å; Y456-F466 HydrophobicContact CE1-CD1 4.04Å; Y456-F466 HydrophobicContact CE1-CE1 4.38Å; Y456-H467 AromaticContact CE2-ND1 3.94Å; Y456-H467 AromaticContact CZ-ND1 3.68Å; Y456-H467 PolarHBondContact OH-ND1 3.44Å; Y456-V470 HydrophobicContact CE1-CG2 3.99Å
457	Q	95.1	Very high	93.5	Very high	23 Å²	23	22.8 Å²	22.8	11%	0.107	13%	0.129	C	C	.	.	H	α-helix	trans	-79.5	-20.1	173.2	-71.8	169.3	100.5	0	0	112.8	W246 L249 W453 T455	W246-Q457 PolarHBondContact O-OE1 3.16Å; L249-Q457 HydrophobicContact CB-CB 3.83Å; L249-Q457 HydrophobicContact CD1-CB 4.06Å; W453-Q457 PolarHBondContact O-N 2.88Å; W453-Q457 VanDerWaalsContact O-N 3.12Å; W453-Q457 PolarHBondContact O-NE2 3.31Å; T455-Q457 VanDerWaalsContact C-N 3.29Å; T455-Q457 PolarHBondContact O-N 2.94Å
458	A	94.8	Very high	93.7	Very high	4 Å²	4	22.8 Å²	22.8	3%	0.033	13%	0.131	C	C	.	.	H	α-helix	trans	-79.6	-25.7	173.1	0	0	0	0	0	113.8	R230 W234 D454 T455 A460	R230-A458 HydrophobicContact CB-CB 4.48Å; R230-A458 WeakPolarHBondContact CB-O 3.48Å; R230-A458 WeakPolarHBondContact CD-O 3.37Å; R230-A458 WeakPolarHBondContact CG-O 3.42Å; R230-A458 WeakPolarHBondContact O-CB 3.13Å; W234-A458 HydrophobicContact CB-CB 4.04Å; D454-A458 PolarHBondContact O-N 3.08Å; T455-A458 WeakPolarHBondContact O-CA 3.48Å; T455-A458 WeakPolarHBondContact O-CB 3.48Å; T455-A458 PolarHBondContact O-N 2.86Å; A458-A460 PolarHBondContact O-N 2.94Å; A458-A460 VanDerWaalsContact O-N 3.09Å
459	E	92	Very high	93.7	Very high	19 Å²	19	23.2 Å²	23.2	9%	0.089	13%	0.132	C	C	.	.			trans	-69.4	102.5	-172.6	-172.4	67.8	-167.7	0	0	112.5	W234 T455 E461 G462 F466 K519	W234-E459 PolarHBondContact NE1-OE2 3.27Å; T455-E459 PolarHBondContact O-N 3.21Å; E459-E461 VanDerWaalsContact C-N 3.31Å; E459-E461 PolarHBondContact O-N 3.39Å; E459-G462 PolarHBondContact O-N 2.96Å; E459-F466 HydrophobicContact CG-CB 3.91Å; E459-F466 HydrophobicContact CG-CD1 4.22Å; E459-F466 HydrophobicContact CG-CG 4.26Å; E459-K519 IonicContact OE1-NZ 3.17Å; E459-K519 PolarHBondContact OE1-NZ 3.4Å
460	A	80.8	Confident	93.8	Very high	70 Å²	70	23.2 Å²	23.2	58%	0.579	13%	0.132	S	C	*	.	T	Hydrogen-bonded Turn	trans	-62.3	-30.1	-173.5	0	0	0	0	0	114.7	A458 G462	A458-A460 PolarHBondContact O-N 2.94Å; A458-A460 VanDerWaalsContact O-N 3.09Å; A460-G462 PolarHBondContact O-N 3.28Å
461	E	79.1	Confident	93.8	Very high	138 Å²	138	22.7 Å²	22.7	65%	0.645	13%	0.129	S	C	*	.	T	Hydrogen-bonded Turn	trans	-80.5	-1.7	175.5	-69.1	177.5	-172.7	0	0	113.6	E459 K519	E459-E461 VanDerWaalsContact C-N 3.31Å; E459-E461 PolarHBondContact O-N 3.39Å; E461-K519 IonicContact OE1-NZ 2.67Å; E461-K519 WeakPolarHBondContact OE2-CE 3.27Å; E461-K519 IonicContact OE2-NZ 3.97Å; E461-K519 PolarHBondContact OE2-NZ 3.28Å
462	G	79.6	Confident	93.9	Very high	31 Å²	31	21.9 Å²	21.9	32%	0.32	13%	0.126	S	C	.	.			trans	90.3	124.4	179.2	0	0	0	0	0	113.6	E459 A460 S464 H465	E459-G462 PolarHBondContact O-N 2.96Å; A460-G462 PolarHBondContact O-N 3.28Å; G462-S464 PolarHBondContact O-N 2.96Å; G462-H465 PolarHBondContact O-N 3.06Å
463	F	91.6	Very high	93.9	Very high	18 Å²	18	22 Å²	22	8%	0.079	13%	0.127	C	C	.	.	H	α-helix	trans	-54.8	-26	-177.4	76.9	-83.8	0	0	0	115.1	L384 I388 L439 Y456 H465 F466 H467	L384-F463 HydrophobicContact CD1-CD1 4.26Å; L384-F463 HydrophobicContact CD1-CE1 3.63Å; L384-F463 HydrophobicContact CD1-CE2 4Å; L384-F463 HydrophobicContact CD1-CZ 3.47Å; L384-F463 VanDerWaalsContact CD1-CZ 3.47Å; L384-F463 HydrophobicContact CG-CE1 4.38Å; L384-F463 HydrophobicContact CG-CZ 3.96Å; I388-F463 HydrophobicContact CD1-CE2 4.32Å; I388-F463 HydrophobicContact CD1-CZ 4.13Å; I388-F463 HydrophobicContact CG1-CZ 4.22Å; I388-F463 HydrophobicContact CG2-CE2 3.88Å; I388-F463 HydrophobicContact CG2-CZ 3.71Å; L439-F463 HydrophobicContact CD1-CE2 3.77Å; L439-F463 HydrophobicContact CD1-CZ 4.48Å; L439-F463 HydrophobicContact CD2-CE2 4.12Å; Y456-F463 HydrophobicContact CD1-CB 4Å; Y456-F463 HydrophobicContact CD2-CB 4.28Å; Y456-F463 HydrophobicContact CD2-CD2 4.13Å; Y456-F463 HydrophobicContact CD2-CG 4.49Å; Y456-F463 HydrophobicContact CG-CB 3.7Å; Y456-F463 HydrophobicContact CG-CD2 4.4Å; Y456-F463 HydrophobicContact CG-CG 4.33Å; F463-H465 PolarHBondContact O-N 3.35Å; F463-F466 PolarHBondContact O-N 3.48Å; F463-F466 VanDerWaalsContact O-N 3.14Å; F463-H467 WeakPolarHBondContact O-CB 3.15Å; F463-H467 PolarHBondContact O-N 3.2Å
464	S	91.7	Very high	93.9	Very high	33 Å²	33	21.9 Å²	21.9	23%	0.231	13%	0.127	C	C	.	.	H	α-helix	trans	-56.3	-36.4	-178.2	-171.6	0	0	0	0	112.8	G387 I388 K402 G462	G387-S464 WeakPolarHBondContact O-CB 3.43Å; G387-S464 PolarHBondContact O-OG 3.21Å; I388-S464 WeakPolarHBondContact CG2-OG 3.37Å; K402-S464 PolarHBondContact NZ-OG 3.49Å; G462-S464 PolarHBondContact O-N 2.96Å
465	H	91.9	Very high	93.9	Very high	82 Å²	82	21.9 Å²	21.9	38%	0.38	13%	0.127	S	C	.	.	H	α-helix	trans	-82.1	-42.6	173.6	-178.7	-146.5	0	0	0	111.7	G462 F463 H467 L468 Y469	G462-H465 PolarHBondContact O-N 3.06Å; F463-H465 PolarHBondContact O-N 3.35Å; H465-H467 VanDerWaalsContact C-N 3.35Å; H465-H467 PolarHBondContact O-N 2.91Å; H465-L468 VanDerWaalsContact O-CB 3.23Å; H465-L468 WeakPolarHBondContact O-CB 3.42Å; H465-L468 PolarHBondContact O-N 2.82Å; H465-Y469 AromaticContact CD2-CE2 3.71Å; H465-Y469 AromaticContact CE1-CE2 3.88Å; H465-Y469 AromaticContact NE2-CE2 3.4Å; H465-Y469 WeakPolarHBondContact NE2-CE2 3.49Å; H465-Y469 AromaticContact NE2-CZ 3.69Å; H465-Y469 PolarHBondContact NE2-OH 3.49Å; H465-Y469 VanDerWaalsContact NE2-OH 3.08Å; H465-Y469 WeakPolarHBondContact O-CD2 3.46Å
466	F	96.3	Very high	93.8	Very high	1 Å²	1	23.4 Å²	23.4	0%	0.004	14%	0.135	C	C	.	.	H	α-helix	trans	-66.1	-34.2	-177.7	-178.1	-131.6	0	0	0	113.5	W234 T455 Y456 E459 F463 L468 Y469 V470 L512 A515 K519	W234-F466 HydrophobicContact CZ2-CE1 4.22Å; W234-F466 AromaticContact CZ2-CZ 3.81Å; W234-F466 HydrophobicContact CZ2-CZ 3.81Å; T455-F466 HydrophobicContact CG2-CE1 4.04Å; Y456-F466 HydrophobicContact CD1-CD1 4.1Å; Y456-F466 HydrophobicContact CE1-CD1 4.04Å; Y456-F466 HydrophobicContact CE1-CE1 4.38Å; E459-F466 HydrophobicContact CG-CB 3.91Å; E459-F466 HydrophobicContact CG-CD1 4.22Å; E459-F466 HydrophobicContact CG-CG 4.26Å; F463-F466 PolarHBondContact O-N 3.48Å; F463-F466 VanDerWaalsContact O-N 3.14Å; F466-L468 PolarHBondContact O-N 2.95Å; F466-L468 VanDerWaalsContact O-N 3.13Å; F466-Y469 PolarHBondContact O-N 3.12Å; F466-V470 HydrophobicContact CD1-CG2 4.39Å; F466-V470 HydrophobicContact CE1-CG2 4.1Å; F466-V470 HydrophobicContact CE2-CG2 4.44Å; F466-V470 HydrophobicContact CZ-CG2 4.12Å; F466-V470 PolarHBondContact O-N 3.1Å; F466-V470 VanDerWaalsContact O-N 3.13Å; F466-L512 HydrophobicContact CE1-CD2 3.54Å; F466-L512 HydrophobicContact CZ-CD2 3.78Å; F466-A515 HydrophobicContact CE2-CB 3.81Å; F466-A515 HydrophobicContact CZ-CB 4Å; F466-K519 HydrophobicContact CD2-CD 4.17Å
467	H	98	Very high	93.8	Very high	4 Å²	4	28.8 Å²	28.8	2%	0.019	16%	0.16	C	C	.	.	H	α-helix	trans	-55.2	-29.6	175	179.9	60.3	0	0	0	113	W435 M436 Y456 F463 H465 V470 C471	W435-H467 PolarHBondContact O-NE2 3.49Å; M436-H467 VanDerWaalsContact SD-CD2 3.58Å; Y456-H467 AromaticContact CE2-ND1 3.94Å; Y456-H467 AromaticContact CZ-ND1 3.68Å; Y456-H467 PolarHBondContact OH-ND1 3.44Å; F463-H467 WeakPolarHBondContact O-CB 3.15Å; F463-H467 PolarHBondContact O-N 3.2Å; H465-H467 VanDerWaalsContact C-N 3.35Å; H465-H467 PolarHBondContact O-N 2.91Å; H467-V470 PolarHBondContact O-N 2.72Å; H467-C471 PolarHBondContact O-N 3.16Å; H467-C471 PolarHBondContact O-SG 3.24Å
468	L	96.9	Very high	94	Very high	20 Å²	20	29.2 Å²	29.2	11%	0.105	16%	0.161	C	C	.	.	H	α-helix	trans	-60.5	-45.2	173.9	-175	64.8	0	0	0	112.2	K402 A405 L406 L409 M436 H465 F466 C471 A472	K402-L468 WeakPolarHBondContact O-CD1 3.38Å; A405-L468 HydrophobicContact CB-CD1 3.95Å; A405-L468 HydrophobicContact CB-CD2 3.81Å; L406-L468 HydrophobicContact CB-CD1 3.86Å; L406-L468 HydrophobicContact CD1-CD1 4.4Å; L409-L468 HydrophobicContact CD2-CD2 4.22Å; L409-L468 HydrophobicContact CD2-CG 3.89Å; M436-L468 HydrophobicContact CE-CD1 4Å; H465-L468 VanDerWaalsContact O-CB 3.23Å; H465-L468 WeakPolarHBondContact O-CB 3.42Å; H465-L468 PolarHBondContact O-N 2.82Å; F466-L468 PolarHBondContact O-N 2.95Å; F466-L468 VanDerWaalsContact O-N 3.13Å; L468-C471 PolarHBondContact O-N 3.17Å; L468-A472 PolarHBondContact O-N 3.13Å
469	Y	97.7	Very high	94.1	Very high	9 Å²	9	33.1 Å²	33.1	4%	0.035	18%	0.175	C	C	.	.	H	α-helix	trans	-75	-30	179.1	-55.6	-86.5	0	0	0	111.8	L409 H465 F466 A472 A473 A515 L518 K519 F522	L409-Y469 HydrophobicContact CD1-CD1 4.29Å; L409-Y469 HydrophobicContact CD1-CE1 3.96Å; L409-Y469 HydrophobicContact CD2-CD1 3.63Å; L409-Y469 HydrophobicContact CD2-CE1 3.83Å; L409-Y469 HydrophobicContact CD2-CG 4.29Å; H465-Y469 AromaticContact CD2-CE2 3.71Å; H465-Y469 AromaticContact CE1-CE2 3.88Å; H465-Y469 AromaticContact NE2-CE2 3.4Å; H465-Y469 WeakPolarHBondContact NE2-CE2 3.49Å; H465-Y469 AromaticContact NE2-CZ 3.69Å; H465-Y469 PolarHBondContact NE2-OH 3.49Å; H465-Y469 VanDerWaalsContact NE2-OH 3.08Å; H465-Y469 WeakPolarHBondContact O-CD2 3.46Å; F466-Y469 PolarHBondContact O-N 3.12Å; Y469-A472 PolarHBondContact O-N 3.35Å; Y469-A473 WeakPolarHBondContact O-CB 3.1Å; Y469-A473 PolarHBondContact O-N 2.97Å; Y469-A515 WeakPolarHBondContact CB-O 3.28Å; Y469-L518 HydrophobicContact CD1-CB 4.09Å; Y469-K519 HydrophobicContact CD1-CB 4.2Å; Y469-K519 HydrophobicContact CD2-CB 3.96Å; Y469-K519 HydrophobicContact CD2-CG 4.07Å; Y469-K519 HydrophobicContact CE1-CB 4.46Å; Y469-K519 HydrophobicContact CE2-CB 4.24Å; Y469-K519 HydrophobicContact CE2-CG 3.98Å; Y469-K519 HydrophobicContact CG-CB 3.94Å; Y469-F522 HydrophobicContact CE1-CB 4.42Å
470	V	98.6	Very high	94.4	Very high	0 Å²	0	40 Å²	40	0%	0	20%	0.204	C	C	.	.	H	α-helix	trans	-63.9	-44.6	169.3	179.7	0	0	0	0	110.8	L440 L452 Y456 F466 H467 A472 A473 F474 L511 L512 A515	L440-V470 HydrophobicContact CD1-CG1 3.82Å; L452-V470 HydrophobicContact CD1-CG1 4.13Å; L452-V470 HydrophobicContact CD1-CG2 4.49Å; Y456-V470 HydrophobicContact CE1-CG2 3.99Å; F466-V470 HydrophobicContact CD1-CG2 4.39Å; F466-V470 HydrophobicContact CE1-CG2 4.1Å; F466-V470 HydrophobicContact CE2-CG2 4.44Å; F466-V470 HydrophobicContact CZ-CG2 4.12Å; F466-V470 PolarHBondContact O-N 3.1Å; F466-V470 VanDerWaalsContact O-N 3.13Å; H467-V470 PolarHBondContact O-N 2.72Å; V470-A472 VanDerWaalsContact C-N 3.3Å; V470-A472 PolarHBondContact O-N 3.14Å; V470-A473 PolarHBondContact O-N 3.2Å; V470-F474 WeakPolarHBondContact O-CB 3.31Å; V470-F474 PolarHBondContact O-N 3.4Å; V470-L511 HydrophobicContact CG1-CD1 4.39Å; V470-L511 HydrophobicContact CG1-CD2 3.93Å; V470-L511 HydrophobicContact CG1-CG 4.12Å; V470-L512 HydrophobicContact CG2-CD2 4.22Å; V470-A515 HydrophobicContact CB-CB 4.27Å; V470-A515 HydrophobicContact CG2-CB 3.63Å
471	C	98.7	Very high	95.3	Very high	0 Å²	0	40.1 Å²	40.1	0%	0	19%	0.193	C	C	.	.	H	α-helix	trans	-62.2	-35.2	173.7	-74.4	0	0	0	0	112.8	L406 W435 M436 H467 L468 L475	L406-C471 HydrophobicContact CD1-CB 3.89Å; L406-C471 HydrophobicContact CD2-CB 4.04Å; W435-C471 HydrophobicContact CE3-CB 4.19Å; M436-C471 HydrophobicContact CE-CB 3.92Å; H467-C471 PolarHBondContact O-N 3.16Å; H467-C471 PolarHBondContact O-SG 3.24Å; L468-C471 PolarHBondContact O-N 3.17Å; C471-L475 WeakPolarHBondContact O-CB 3.49Å; C471-L475 PolarHBondContact O-N 2.77Å
472	A	98.4	Very high	96.2	Very high	0 Å²	0	33.5 Å²	33.5	0%	0	16%	0.162	C	C	.	.	H	α-helix	trans	-69.8	-48.9	175.1	0	0	0	0	0	112.2	L406 L409 V410 I413 L468 Y469 V470 F474 L475 I476 L518	L406-A472 HydrophobicContact CD1-CB 3.94Å; L409-A472 HydrophobicContact CD2-CB 3.76Å; L409-A472 HydrophobicContact CG-CB 4.21Å; V410-A472 HydrophobicContact CG2-CB 4.35Å; I413-A472 HydrophobicContact CD1-CB 4.23Å; L468-A472 PolarHBondContact O-N 3.13Å; Y469-A472 PolarHBondContact O-N 3.35Å; V470-A472 VanDerWaalsContact C-N 3.3Å; V470-A472 PolarHBondContact O-N 3.14Å; A472-F474 VanDerWaalsContact C-N 3.34Å; A472-F474 PolarHBondContact O-N 3.05Å; A472-L475 PolarHBondContact O-N 3.39Å; A472-I476 WeakPolarHBondContact O-CD1 3.15Å; A472-I476 VanDerWaalsContact O-CG1 3.3Å; A472-I476 WeakPolarHBondContact O-CG1 3.48Å; A472-I476 PolarHBondContact O-N 2.78Å; A472-L518 HydrophobicContact CB-CD1 4.26Å
473	A	98.5	Very high	97.1	Very high	2 Å²	2	34.2 Å²	34.2	2%	0.017	16%	0.158	C	C	.	.	H	α-helix	trans	-59.8	-43.2	176.6	0	0	0	0	0	111.8	Y469 V470 L475 I476 E477 L511 E514 A515 L518	Y469-A473 WeakPolarHBondContact O-CB 3.1Å; Y469-A473 PolarHBondContact O-N 2.97Å; V470-A473 PolarHBondContact O-N 3.2Å; A473-L475 PolarHBondContact O-N 2.74Å; A473-I476 PolarHBondContact O-N 2.67Å; A473-I476 VanDerWaalsContact O-N 3.15Å; A473-E477 PolarHBondContact O-N 2.8Å; A473-L511 HydrophobicContact CB-CD1 3.59Å; A473-E514 HydrophobicContact CB-CB 4.15Å; A473-E514 HydrophobicContact CB-CG 3.72Å; A473-A515 HydrophobicContact CB-CB 4.07Å; A473-L518 HydrophobicContact CB-CD1 3.97Å
474	F	98.6	Very high	97.4	Very high	0 Å²	0	37.9 Å²	37.9	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-62.1	-32.5	178	-175.1	-122.1	0	0	0	112.4	W435 L440 E443 L444 V470 A472 W478 L498 T500 W503 L511	W435-F474 HydrophobicContact CE3-CD1 4.46Å; W435-F474 AromaticContact CH2-CD1 3.95Å; W435-F474 HydrophobicContact CH2-CD1 3.95Å; W435-F474 HydrophobicContact CH2-CE1 4.37Å; W435-F474 HydrophobicContact CZ2-CD1 4.2Å; W435-F474 HydrophobicContact CZ2-CE1 4.17Å; W435-F474 HydrophobicContact CZ3-CD1 4.08Å; L440-F474 HydrophobicContact CD1-CD1 4.46Å; L440-F474 HydrophobicContact CD2-CD1 3.69Å; L440-F474 HydrophobicContact CD2-CE1 3.84Å; E443-F474 HydrophobicContact CB-CE1 3.71Å; E443-F474 HydrophobicContact CB-CZ 3.82Å; E443-F474 HydrophobicContact CG-CE1 4.23Å; L444-F474 HydrophobicContact CD2-CE2 4.01Å; L444-F474 HydrophobicContact CD2-CZ 4.37Å; V470-F474 WeakPolarHBondContact O-CB 3.31Å; V470-F474 PolarHBondContact O-N 3.4Å; A472-F474 VanDerWaalsContact C-N 3.34Å; A472-F474 PolarHBondContact O-N 3.05Å; F474-W478 AromaticContact CE2-NE1 3.83Å; F474-L498 HydrophobicContact CD1-CD1 4.07Å; F474-L498 HydrophobicContact CE1-CD1 3.44Å; F474-L498 VanDerWaalsContact CE1-CD1 3.44Å; F474-L498 HydrophobicContact CZ-CB 4.2Å; F474-L498 HydrophobicContact CZ-CD1 3.76Å; F474-T500 HydrophobicContact CE2-CG2 3.7Å; F474-T500 HydrophobicContact CZ-CG2 3.78Å; F474-W503 AromaticContact CD2-CH2 3.8Å; F474-W503 HydrophobicContact CD2-CH2 3.8Å; F474-W503 HydrophobicContact CD2-CZ3 4.06Å; F474-W503 AromaticContact CE2-CH2 3.76Å; F474-W503 HydrophobicContact CE2-CH2 3.76Å; F474-W503 HydrophobicContact CE2-CZ2 4.44Å; F474-W503 AromaticContact CE2-CZ3 3.93Å; F474-W503 HydrophobicContact CE2-CZ3 3.93Å; F474-L511 HydrophobicContact CB-CD1 3.81Å; F474-L511 HydrophobicContact CB-CD2 4.38Å; F474-L511 HydrophobicContact CD2-CD2 4.13Å; F474-L511 VanDerWaalsContact N-CD1 3.27Å
475	L	98	Very high	97.6	Very high	0 Å²	0	39 Å²	39	0%	0	19%	0.187	C	C	.	.	H	α-helix	trans	-77	-36.8	176.1	-160.9	156.6	0	0	0	111.7	I417 F421 F431 W435 C471 A472 A473 W478 I482	I417-L475 HydrophobicContact CD1-CD2 3.99Å; I417-L475 HydrophobicContact CG2-CD2 3.47Å; I417-L475 VanDerWaalsContact CG2-CD2 3.47Å; F421-L475 HydrophobicContact CE2-CD1 3.99Å; F421-L475 HydrophobicContact CE2-CD2 4.2Å; F421-L475 HydrophobicContact CZ-CD1 4.08Å; F421-L475 HydrophobicContact CZ-CD2 3.87Å; F421-L475 HydrophobicContact CZ-CG 4.32Å; F431-L475 HydrophobicContact CE2-CD1 3.68Å; F431-L475 HydrophobicContact CZ-CD1 3.86Å; W435-L475 HydrophobicContact CH2-CB 4.18Å; W435-L475 HydrophobicContact CH2-CD1 4.06Å; W435-L475 HydrophobicContact CH2-CG 4.2Å; W435-L475 HydrophobicContact CZ3-CB 4.12Å; W435-L475 HydrophobicContact CZ3-CD1 4Å; W435-L475 HydrophobicContact CZ3-CG 4.41Å; C471-L475 WeakPolarHBondContact O-CB 3.49Å; C471-L475 PolarHBondContact O-N 2.77Å; A472-L475 PolarHBondContact O-N 3.39Å; A473-L475 PolarHBondContact O-N 2.74Å; L475-W478 PolarHBondContact O-N 2.72Å; L475-I482 HydrophobicContact CD2-CD1 3.93Å; L475-I482 HydrophobicContact CG-CD1 4.23Å; L475-I482 WeakPolarHBondContact O-CD1 3.45Å
476	I	96.6	Very high	97.8	Very high	33 Å²	33	40 Å²	40	17%	0.169	20%	0.199	C	C	.	.	H	α-helix	trans	-69.3	-33.8	177.7	-69.2	160.3	0	0	0	112	I413 A472 A473 W478 R479 L518	I413-I476 HydrophobicContact CB-CD1 4.32Å; I413-I476 HydrophobicContact CD1-CD1 4.3Å; I413-I476 HydrophobicContact CG2-CD1 3.57Å; A472-I476 WeakPolarHBondContact O-CD1 3.15Å; A472-I476 VanDerWaalsContact O-CG1 3.3Å; A472-I476 WeakPolarHBondContact O-CG1 3.48Å; A472-I476 PolarHBondContact O-N 2.78Å; A473-I476 PolarHBondContact O-N 2.67Å; A473-I476 VanDerWaalsContact O-N 3.15Å; I476-W478 PolarHBondContact O-N 2.92Å; I476-R479 WeakPolarHBondContact O-CB 3.31Å; I476-R479 PolarHBondContact O-N 3.16Å; I476-L518 HydrophobicContact CD1-CD1 3.86Å
477	E	97.7	Very high	97.9	Very high	118 Å²	118	43 Å²	43	55%	0.551	22%	0.215	S	C	*	.	H	α-helix	trans	-52.8	-44.3	175.5	-174.3	59.6	-155.6	0	0	111.6	A473 R479 W503	A473-E477 PolarHBondContact O-N 2.8Å; E477-R479 VanDerWaalsContact C-N 3.3Å; E477-R479 PolarHBondContact O-N 3.12Å; E477-W503 HydrophobicContact CG-CH2 4.28Å; E477-W503 HydrophobicContact CG-CZ2 4.14Å
478	W	98.1	Very high	97.9	Very high	32 Å²	32	47.1 Å²	47.1	12%	0.121	23%	0.233	C	C	.	.	T	Hydrogen-bonded Turn	trans	-89.5	20.2	179.9	-55	107.2	0	0	0	114	F474 L475 I476 K480 E481 I482 L498 P499 T500 W503	F474-W478 AromaticContact CE2-NE1 3.83Å; L475-W478 PolarHBondContact O-N 2.72Å; I476-W478 PolarHBondContact O-N 2.92Å; W478-K480 VanDerWaalsContact C-N 3.26Å; W478-K480 PolarHBondContact O-N 2.86Å; W478-E481 WeakPolarHBondContact CA-OE2 3.3Å; W478-E481 HydrophobicContact CE3-CG 4.18Å; W478-E481 PolarHBondContact O-N 2.68Å; W478-I482 HydrophobicContact CB-CD1 4.17Å; W478-I482 HydrophobicContact CB-CG1 4.43Å; W478-I482 WeakPolarHBondContact O-CB 3.29Å; W478-I482 VanDerWaalsContact O-CG1 3.29Å; W478-I482 WeakPolarHBondContact O-CG1 3.27Å; W478-I482 PolarHBondContact O-N 2.96Å; W478-L498 HydrophobicContact CB-CD2 4.07Å; W478-L498 HydrophobicContact CD2-CD2 4.3Å; W478-L498 HydrophobicContact CG-CD1 4.5Å; W478-L498 HydrophobicContact CG-CD2 3.74Å; W478-P499 HydrophobicContact CE3-CG 4.29Å; W478-P499 HydrophobicContact CH2-CG 3.56Å; W478-P499 HydrophobicContact CZ2-CG 4.2Å; W478-P499 HydrophobicContact CZ3-CG 3.61Å; W478-T500 HydrophobicContact CZ2-CG2 4.15Å; W478-W503 HydrophobicContact CH2-CZ2 4.48Å; W478-W503 AromaticContact CZ2-CE2 3.95Å; W478-W503 AromaticContact CZ2-CZ2 3.62Å; W478-W503 HydrophobicContact CZ2-CZ2 3.62Å; W478-W503 AromaticContact CZ2-NE1 3.9Å
479	R	98.2	Very high	97.9	Very high	86 Å²	86	53 Å²	53	33%	0.325	26%	0.26	S	S	.	.	H	α-helix	trans	-50	-43.5	-177.8	173.9	-178.4	-137.1	-91.5	-2.1	113.1	D414 D416 I417 I476 E477 L483	D414-R479 IonicContact OD1-CZ 2.7Å; D414-R479 IonicContact OD1-NE 3.02Å; D414-R479 IonicContact OD1-NH2 3.68Å; D414-R479 PolarHBondContact OD1-NH2 3.48Å; D414-R479 IonicContact OD2-CZ 3.15Å; D414-R479 IonicContact OD2-NE 2.86Å; D414-R479 PolarHBondContact OD2-NE 2.86Å; D414-R479 IonicContact OD2-NH2 3.6Å; D414-R479 PolarHBondContact OD2-NH2 3.42Å; D416-R479 IonicContact OD2-CZ 3.26Å; D416-R479 IonicContact OD2-NH1 3.2Å; D416-R479 IonicContact OD2-NH2 3.7Å; D416-R479 PolarHBondContact OD2-NH2 3.49Å; I417-R479 HydrophobicContact CD1-CB 3.98Å; I417-R479 HydrophobicContact CD1-CG 3.99Å; I417-R479 HydrophobicContact CG1-CG 4.29Å; I476-R479 WeakPolarHBondContact O-CB 3.31Å; I476-R479 PolarHBondContact O-N 3.16Å; E477-R479 VanDerWaalsContact C-N 3.3Å; E477-R479 PolarHBondContact O-N 3.12Å; R479-L483 HydrophobicContact CG-CD1 3.75Å; R479-L483 HydrophobicContact CG-CG 4.39Å; R479-L483 WeakPolarHBondContact O-CB 3.42Å; R479-L483 VanDerWaalsContact O-CG 3.25Å; R479-L483 WeakPolarHBondContact O-CG 3.4Å; R479-L483 PolarHBondContact O-N 3.44Å
480	K	98.2	Very high	97.9	Very high	162 Å²	162	55 Å²	55	70%	0.704	28%	0.275	S	S	*	.	H	α-helix	trans	-69.4	-46.9	-173.1	-62.5	166.6	-171.4	154.4	0	109.9	W478 L483 C484	W478-K480 VanDerWaalsContact C-N 3.26Å; W478-K480 PolarHBondContact O-N 2.86Å; K480-L483 PolarHBondContact O-N 3.18Å; K480-C484 WeakPolarHBondContact O-CB 3.13Å; K480-C484 PolarHBondContact O-N 3.41Å; K480-C484 PolarHBondContact O-SG 2.97Å
481	E	98.3	Very high	97.8	Very high	73 Å²	73	55 Å²	55	34%	0.341	28%	0.275	S	S	.	.	H	α-helix	trans	-63.7	-45.8	179.9	-63.7	64.6	-144.7	0	0	110	W478 C484 M485 L494	W478-E481 WeakPolarHBondContact CA-OE2 3.3Å; W478-E481 HydrophobicContact CE3-CG 4.18Å; W478-E481 PolarHBondContact O-N 2.68Å; E481-C484 PolarHBondContact O-N 2.93Å; E481-M485 WeakPolarHBondContact O-CG 3.41Å; E481-M485 PolarHBondContact O-N 2.77Å; E481-L494 HydrophobicContact CB-CD2 3.92Å
482	I	98.4	Very high	97.8	Very high	0 Å²	0	56.1 Å²	56.1	0%	0	28%	0.281	C	S	.	.	H	α-helix	trans	-56	-56.4	173.4	-75.3	167	0	0	0	110.8	I417 H420 F421 L475 W478 C484 M485 L491 L494 L495	I417-I482 HydrophobicContact CG1-CG2 4.45Å; H420-I482 PolarHBondContact NE2-O 2.83Å; F421-I482 HydrophobicContact CE1-CG2 3.71Å; F421-I482 HydrophobicContact CZ-CG2 4.45Å; L475-I482 HydrophobicContact CD2-CD1 3.93Å; L475-I482 HydrophobicContact CG-CD1 4.23Å; L475-I482 WeakPolarHBondContact O-CD1 3.45Å; W478-I482 HydrophobicContact CB-CD1 4.17Å; W478-I482 HydrophobicContact CB-CG1 4.43Å; W478-I482 WeakPolarHBondContact O-CB 3.29Å; W478-I482 VanDerWaalsContact O-CG1 3.29Å; W478-I482 WeakPolarHBondContact O-CG1 3.27Å; W478-I482 PolarHBondContact O-N 2.96Å; I482-C484 PolarHBondContact O-N 3.28Å; I482-M485 PolarHBondContact O-N 2.81Å; I482-M485 VanDerWaalsContact O-N 3.09Å; I482-L491 HydrophobicContact CB-CD1 4.46Å; I482-L491 HydrophobicContact CG1-CD1 4.49Å; I482-L491 HydrophobicContact CG2-CD1 4.04Å; I482-L494 HydrophobicContact CG1-CD2 4.07Å; I482-L495 HydrophobicContact CD1-CD2 3.86Å; I482-L495 HydrophobicContact CG1-CD2 4.14Å
483	L	98.2	Very high	97.7	Very high	45 Å²	45	61 Å²	61	24%	0.236	31%	0.305	C	S	.	.	H	α-helix	trans	-69	-17.2	-175.3	-67.2	176.1	0	0	0	113.6	D416 I417 H420 R479 K480	D416-L483 HydrophobicContact CB-CD1 4.34Å; D416-L483 HydrophobicContact CB-CD2 4.34Å; I417-L483 HydrophobicContact CG1-CD2 4.34Å; I417-L483 HydrophobicContact CG1-CG 4.41Å; H420-L483 HydrophobicContact CB-CD2 3.68Å; H420-L483 WeakPolarHBondContact CE1-CD2 3.36Å; H420-L483 WeakPolarHBondContact NE2-CA 3.28Å; H420-L483 PolarHBondContact NE2-O 2.97Å; R479-L483 HydrophobicContact CG-CD1 3.75Å; R479-L483 HydrophobicContact CG-CG 4.39Å; R479-L483 WeakPolarHBondContact O-CB 3.42Å; R479-L483 VanDerWaalsContact O-CG 3.25Å; R479-L483 WeakPolarHBondContact O-CG 3.4Å; R479-L483 PolarHBondContact O-N 3.44Å; K480-L483 PolarHBondContact O-N 3.18Å
484	C	97.9	Very high	97.7	Very high	96 Å²	96	62 Å²	62	65%	0.649	31%	0.31	S	S	*	.	H	α-helix	trans	-81.9	-17.3	172.6	-79.1	0	0	0	0	114.3	K480 E481 I482	K480-C484 WeakPolarHBondContact O-CB 3.13Å; K480-C484 PolarHBondContact O-N 3.41Å; K480-C484 PolarHBondContact O-SG 2.97Å; E481-C484 PolarHBondContact O-N 2.93Å; I482-C484 PolarHBondContact O-N 3.28Å
485	M	97.4	Very high	97.7	Very high	57 Å²	57	62 Å²	62	28%	0.281	31%	0.31	S	S	.	.			trans	-73.8	135.2	173.4	-61.9	-57.8	156.1	0	0	109.7	H420 E481 I482 L491 L494	H420-M485 PolarHBondContact NE2-O 2.7Å; E481-M485 WeakPolarHBondContact O-CG 3.41Å; E481-M485 PolarHBondContact O-N 2.77Å; I482-M485 PolarHBondContact O-N 2.81Å; I482-M485 VanDerWaalsContact O-N 3.09Å; M485-L491 HydrophobicContact CB-CB 3.85Å; M485-L491 HydrophobicContact CB-CD1 4.17Å; M485-L491 HydrophobicContact CG-CB 4.47Å; M485-L491 HydrophobicContact CG-CD1 4.5Å; M485-L494 HydrophobicContact CE-CD2 4.08Å; M485-L494 HydrophobicContact CG-CD2 3.95Å
486	V	95.9	Very high	97.6	Very high	103 Å²	103	64.4 Å²	64.4	62%	0.624	32%	0.321	S	S	*	.			trans	-122.9	17.5	-173.6	-64.8	0	0	0	0	113.7	Y424	Y424-V486 WeakPolarHBondContact CE1-O 3.48Å; Y424-V486 WeakPolarHBondContact OH-CA 3.49Å
487	D	97	Very high	97.5	Very high	62 Å²	62	66.4 Å²	66.4	33%	0.332	33%	0.332	S	S	.	.	S	Bend	trans	-149.3	155.7	174.2	78	88.6	0	0	0	111.6	Q489 S490 L491	D487-Q489 PolarHBondContact O-N 3.43Å; D487-Q489 WeakPolarHBondContact OD1-CA 3.46Å; D487-Q489 WeakPolarHBondContact OD1-CB 3.41Å; D487-Q489 PolarHBondContact OD1-N 2.95Å; D487-S490 PolarHBondContact OD1-N 3.31Å; D487-S490 PolarHBondContact OD1-OG 3.5Å; D487-S490 WeakPolarHBondContact OD2-CB 3.5Å; D487-S490 PolarHBondContact OD2-OG 2.89Å; D487-L491 VanDerWaalsContact O-CB 3.25Å; D487-L491 WeakPolarHBondContact O-CB 3.27Å; D487-L491 PolarHBondContact O-N 2.99Å
488	F	97.8	Very high	97.4	Very high	92 Å²	92	61.1 Å²	61.1	40%	0.404	31%	0.307	S	S	.	.	H	α-helix	trans	-57.1	-41.9	-179.9	169.7	-98	0	0	0	113.6	Y424 V426 L492	Y424-F488 WeakPolarHBondContact O-CB 3.39Å; Y424-F488 WeakPolarHBondContact O-CD2 3.44Å; V426-F488 HydrophobicContact CG2-CD2 3.62Å; V426-F488 HydrophobicContact CG2-CE2 4.07Å; F488-L492 HydrophobicContact CE1-CD2 4.13Å; F488-L492 HydrophobicContact CE2-CD2 4.24Å; F488-L492 HydrophobicContact CZ-CD2 3.67Å; F488-L492 VanDerWaalsContact O-CB 3.27Å; F488-L492 WeakPolarHBondContact O-CB 3.24Å; F488-L492 PolarHBondContact O-N 3.41Å
489	Q	97.5	Very high	97.3	Very high	144 Å²	144	62.9 Å²	62.9	67%	0.673	32%	0.323	S	S	*	.	H	α-helix	trans	-72.9	-47.2	-171.5	-178.3	179.5	-43.1	0	0	111	D487 M493	D487-Q489 PolarHBondContact O-N 3.43Å; D487-Q489 WeakPolarHBondContact OD1-CA 3.46Å; D487-Q489 WeakPolarHBondContact OD1-CB 3.41Å; D487-Q489 PolarHBondContact OD1-N 2.95Å; Q489-M493 WeakPolarHBondContact O-CB 3.36Å; Q489-M493 WeakPolarHBondContact O-CG 3.4Å; Q489-M493 PolarHBondContact O-N 3.26Å
490	S	97.2	Very high	97.2	Very high	49 Å²	49	58.9 Å²	58.9	34%	0.343	31%	0.308	S	S	.	.	H	α-helix	trans	-65.2	-40.3	177.9	-53.9	0	0	0	0	111.5	D487 M493 L494	D487-S490 PolarHBondContact OD1-N 3.31Å; D487-S490 PolarHBondContact OD1-OG 3.5Å; D487-S490 WeakPolarHBondContact OD2-CB 3.5Å; D487-S490 PolarHBondContact OD2-OG 2.89Å; S490-M493 PolarHBondContact O-N 3.06Å; S490-L494 WeakPolarHBondContact O-CB 3.41Å; S490-L494 PolarHBondContact O-N 3.33Å
491	L	98.4	Very high	96.8	Very high	0 Å²	0	53.6 Å²	53.6	0%	0	29%	0.287	C	S	.	.	H	α-helix	trans	-65.4	-47.3	177.5	179	56.7	0	0	0	112.4	F421 Y424 V426 I482 M485 D487 L494 L495	F421-L491 HydrophobicContact CD1-CD2 4.13Å; F421-L491 HydrophobicContact CE1-CD1 4.22Å; Y424-L491 HydrophobicContact CD2-CD2 4.41Å; V426-L491 HydrophobicContact CB-CD2 4.41Å; V426-L491 HydrophobicContact CG2-CB 4.47Å; V426-L491 HydrophobicContact CG2-CD2 3.75Å; V426-L491 HydrophobicContact CG2-CG 4.05Å; I482-L491 HydrophobicContact CB-CD1 4.46Å; I482-L491 HydrophobicContact CG1-CD1 4.49Å; I482-L491 HydrophobicContact CG2-CD1 4.04Å; M485-L491 HydrophobicContact CB-CB 3.85Å; M485-L491 HydrophobicContact CB-CD1 4.17Å; M485-L491 HydrophobicContact CG-CB 4.47Å; M485-L491 HydrophobicContact CG-CD1 4.5Å; D487-L491 VanDerWaalsContact O-CB 3.25Å; D487-L491 WeakPolarHBondContact O-CB 3.27Å; D487-L491 PolarHBondContact O-N 2.99Å; L491-L494 PolarHBondContact O-N 3.5Å; L491-L495 HydrophobicContact CD1-CD1 3.98Å; L491-L495 HydrophobicContact CD1-CG 4.34Å; L491-L495 HydrophobicContact CG-CD1 4.08Å; L491-L495 WeakPolarHBondContact O-CG 3.48Å; L491-L495 PolarHBondContact O-N 3.23Å
492	L	97.7	Very high	96.3	Very high	25 Å²	25	56.8 Å²	56.8	13%	0.131	30%	0.302	C	S	.	.	H	α-helix	trans	-68	-36.1	177	-175.8	60.3	0	0	0	111.9	Q430 F431 F488 L495 Q496	Q430-L492 HydrophobicContact CB-CD1 3.79Å; Q430-L492 HydrophobicContact CB-CD2 4.43Å; F431-L492 HydrophobicContact CB-CD1 4.42Å; F488-L492 HydrophobicContact CE1-CD2 4.13Å; F488-L492 HydrophobicContact CE2-CD2 4.24Å; F488-L492 HydrophobicContact CZ-CD2 3.67Å; F488-L492 VanDerWaalsContact O-CB 3.27Å; F488-L492 WeakPolarHBondContact O-CB 3.24Å; F488-L492 PolarHBondContact O-N 3.41Å; L492-L495 PolarHBondContact O-N 2.89Å; L492-Q496 HydrophobicContact CD1-CG 4.15Å; L492-Q496 WeakPolarHBondContact O-CB 3.24Å; L492-Q496 WeakPolarHBondContact O-CG 3.22Å; L492-Q496 PolarHBondContact O-N 3.5Å
493	M	96.7	Very high	96.1	Very high	101 Å²	101	57.8 Å²	57.8	50%	0.498	31%	0.306	S	S	.	.	H	α-helix	trans	-60.8	-43.2	172.1	-82.2	-67.8	-57.5	0	0	112	Q489 S490 Q496 N497	Q489-M493 WeakPolarHBondContact O-CB 3.36Å; Q489-M493 WeakPolarHBondContact O-CG 3.4Å; Q489-M493 PolarHBondContact O-N 3.26Å; S490-M493 PolarHBondContact O-N 3.06Å; M493-Q496 PolarHBondContact O-N 2.72Å; M493-N497 WeakPolarHBondContact O-CB 2.86Å; M493-N497 PolarHBondContact O-N 2.95Å; M493-N497 VanDerWaalsContact O-N 3.12Å; M493-N497 PolarHBondContact O-ND2 3.26Å
494	L	97.8	Very high	95.8	Very high	25 Å²	25	56.2 Å²	56.2	13%	0.131	30%	0.3	C	S	.	.	H	α-helix	trans	-61	-53.6	175	175.3	66.2	0	0	0	110.8	E481 I482 M485 S490 L491 Q496 N497 L498	E481-L494 HydrophobicContact CB-CD2 3.92Å; I482-L494 HydrophobicContact CG1-CD2 4.07Å; M485-L494 HydrophobicContact CE-CD2 4.08Å; M485-L494 HydrophobicContact CG-CD2 3.95Å; S490-L494 WeakPolarHBondContact O-CB 3.41Å; S490-L494 PolarHBondContact O-N 3.33Å; L491-L494 PolarHBondContact O-N 3.5Å; L494-Q496 PolarHBondContact O-N 3.14Å; L494-Q496 VanDerWaalsContact O-N 3.17Å; L494-N497 CarbonylContact O-C 3.51Å; L494-N497 VanDerWaalsContact O-C 3.26Å; L494-N497 PolarHBondContact O-N 3.25Å; L494-L498 HydrophobicContact CD1-CD2 3.92Å; L494-L498 HydrophobicContact CG-CD2 3.89Å; L494-L498 VanDerWaalsContact O-CD2 3.31Å; L494-L498 WeakPolarHBondContact O-CD2 3.26Å; L494-L498 WeakPolarHBondContact O-CG 3.37Å; L494-L498 PolarHBondContact O-N 2.92Å; L494-L498 VanDerWaalsContact O-N 3.08Å
495	L	97.9	Very high	95.6	Very high	0 Å²	0	55.2 Å²	55.2	0%	0	29%	0.288	C	S	.	.	H	α-helix	trans	-62.1	-24.1	-178.4	-69.1	165.1	0	0	0	113.8	F421 V426 F431 I482 L491 L492	F421-L495 HydrophobicContact CE1-CD1 3.81Å; F421-L495 HydrophobicContact CE1-CD2 4.36Å; F421-L495 HydrophobicContact CZ-CD1 3.94Å; F421-L495 HydrophobicContact CZ-CD2 3.99Å; V426-L495 HydrophobicContact CG1-CD1 3.97Å; F431-L495 HydrophobicContact CB-CB 4.04Å; F431-L495 HydrophobicContact CD1-CB 4.28Å; F431-L495 HydrophobicContact CD1-CD1 3.87Å; F431-L495 HydrophobicContact CD2-CB 4.37Å; F431-L495 HydrophobicContact CE1-CD1 3.91Å; F431-L495 HydrophobicContact CE2-CD2 4.47Å; F431-L495 HydrophobicContact CG-CB 3.98Å; F431-L495 HydrophobicContact CG-CD1 4.37Å; F431-L495 HydrophobicContact CZ-CD1 4.46Å; I482-L495 HydrophobicContact CD1-CD2 3.86Å; I482-L495 HydrophobicContact CG1-CD2 4.14Å; L491-L495 HydrophobicContact CD1-CD1 3.98Å; L491-L495 HydrophobicContact CD1-CG 4.34Å; L491-L495 HydrophobicContact CG-CD1 4.08Å; L491-L495 WeakPolarHBondContact O-CG 3.48Å; L491-L495 PolarHBondContact O-N 3.23Å; L492-L495 PolarHBondContact O-N 2.89Å
496	Q	96.8	Very high	95.4	Very high	50 Å²	50	59.7 Å²	59.7	23%	0.234	31%	0.308	C	S	.	.	T	Hydrogen-bonded Turn	trans	-94.5	-3.3	174.5	-68.4	-177.1	-2.5	0	0	114.1	Q430 F431 R434 L492 M493 L494	Q430-Q496 PolarHBondContact O-NE2 2.92Å; F431-Q496 HydrophobicContact CB-CG 4.26Å; R434-Q496 PolarHBondContact NH2-O 3.5Å; L492-Q496 HydrophobicContact CD1-CG 4.15Å; L492-Q496 WeakPolarHBondContact O-CB 3.24Å; L492-Q496 WeakPolarHBondContact O-CG 3.22Å; L492-Q496 PolarHBondContact O-N 3.5Å; M493-Q496 PolarHBondContact O-N 2.72Å; L494-Q496 PolarHBondContact O-N 3.14Å; L494-Q496 VanDerWaalsContact O-N 3.17Å
497	N	94.6	Very high	95.5	Very high	75 Å²	75	57.9 Å²	57.9	40%	0.401	29%	0.293	S	S	.	.	S	Bend	trans	-149.1	47.5	-176.9	-54.3	-90.5	0	0	0	111.3	M493 L494	M493-N497 WeakPolarHBondContact O-CB 2.86Å; M493-N497 PolarHBondContact O-N 2.95Å; M493-N497 VanDerWaalsContact O-N 3.12Å; M493-N497 PolarHBondContact O-ND2 3.26Å; L494-N497 CarbonylContact O-C 3.51Å; L494-N497 VanDerWaalsContact O-C 3.26Å; L494-N497 PolarHBondContact O-N 3.25Å
498	L	95.9	Very high	95.5	Very high	6 Å²	6	55 Å²	55	3%	0.031	28%	0.278	C	S	.	.			trans	-60.1	136.9	-179.1	-66.6	169.8	0	0	0	110.7	W435 F474 W478 L494 T500	W435-L498 HydrophobicContact CH2-CD1 4.1Å; W435-L498 HydrophobicContact CZ2-CD1 3.72Å; F474-L498 HydrophobicContact CD1-CD1 4.07Å; F474-L498 HydrophobicContact CE1-CD1 3.44Å; F474-L498 VanDerWaalsContact CE1-CD1 3.44Å; F474-L498 HydrophobicContact CZ-CB 4.2Å; F474-L498 HydrophobicContact CZ-CD1 3.76Å; W478-L498 HydrophobicContact CB-CD2 4.07Å; W478-L498 HydrophobicContact CD2-CD2 4.3Å; W478-L498 HydrophobicContact CG-CD1 4.5Å; W478-L498 HydrophobicContact CG-CD2 3.74Å; L494-L498 HydrophobicContact CD1-CD2 3.92Å; L494-L498 HydrophobicContact CG-CD2 3.89Å; L494-L498 VanDerWaalsContact O-CD2 3.31Å; L494-L498 WeakPolarHBondContact O-CD2 3.26Å; L494-L498 WeakPolarHBondContact O-CG 3.37Å; L494-L498 PolarHBondContact O-N 2.92Å; L494-L498 VanDerWaalsContact O-N 3.08Å; L498-T500 VanDerWaalsContact C-N 3.27Å; L498-T500 HydrophobicContact CB-CG2 4.47Å; L498-T500 PolarHBondContact O-N 2.87Å
499	P	95.2	Very high	95.4	Very high	70 Å²	70	51.7 Å²	51.7	46%	0.455	27%	0.27	S	S	.	.	S	Bend	trans	-82.2	63.5	-163.3	31.3	-33.8	0	0	0	113.8	W478	W478-P499 HydrophobicContact CE3-CG 4.29Å; W478-P499 HydrophobicContact CH2-CG 3.56Å; W478-P499 HydrophobicContact CZ2-CG 4.2Å; W478-P499 HydrophobicContact CZ3-CG 3.61Å
500	T	95.6	Very high	95.4	Very high	1 Å²	1	49.6 Å²	49.6	1%	0.006	26%	0.262	C	S	.	.			trans	-90.1	0.7	-175.8	60.6	0	0	0	0	114.9	E443 L444 P445 F474 W478 L498 H502 W503	E443-T500 WeakPolarHBondContact O-CB 3.26Å; E443-T500 VanDerWaalsContact O-CG2 3.27Å; E443-T500 WeakPolarHBondContact O-CG2 3.33Å; E443-T500 PolarHBondContact O-OG1 2.97Å; L444-T500 HydrophobicContact CD2-CG2 4.05Å; P445-T500 WeakPolarHBondContact CG-O 3.29Å; F474-T500 HydrophobicContact CE2-CG2 3.7Å; F474-T500 HydrophobicContact CZ-CG2 3.78Å; W478-T500 HydrophobicContact CZ2-CG2 4.15Å; L498-T500 VanDerWaalsContact C-N 3.27Å; L498-T500 HydrophobicContact CB-CG2 4.47Å; L498-T500 PolarHBondContact O-N 2.87Å; T500-H502 PolarHBondContact O-N 2.86Å; T500-W503 HydrophobicContact CG2-CD2 4.04Å; T500-W503 HydrophobicContact CG2-CE3 4.34Å; T500-W503 HydrophobicContact CG2-CZ2 4.28Å; T500-W503 WeakPolarHBondContact O-CB 3.44Å; T500-W503 PolarHBondContact O-N 3.46Å
501	I	90.3	Very high	95.5	Very high	51 Å²	51	47.6 Å²	47.6	26%	0.262	25%	0.248	S	C	.	.	T	Hydrogen-bonded Turn	trans	-51.7	-29.8	-175.7	-170.7	-177.6	0	0	0	113.8	L186 R447	L186-I501 HydrophobicContact CD2-CD1 4.5Å; L186-I501 WeakPolarHBondContact O-CD1 3.47Å; L186-I501 VanDerWaalsContact O-CG1 3.27Å; L186-I501 WeakPolarHBondContact O-CG1 3.37Å; R447-I501 PolarHBondContact NH2-O 3.31Å
502	H	89.1	Confident	95.5	Very high	141 Å²	141	47.6 Å²	47.6	65%	0.653	25%	0.248	S	C	*	.	T	Hydrogen-bonded Turn	trans	-89	-15.4	-179.3	-63	-62.8	0	0	0	114.7	T500	T500-H502 PolarHBondContact O-N 2.86Å
503	W	94.1	Very high	95.4	Very high	21 Å²	21	49 Å²	49	8%	0.08	26%	0.263	C	S	.	.			trans	-61.4	150.5	-175.2	-71.2	18.2	0	0	0	112.2	L444 R447 C448 F474 E477 W478 T500 E507 L511	L444-W503 HydrophobicContact CD2-CE3 3.66Å; L444-W503 HydrophobicContact CD2-CZ3 3.9Å; R447-W503 VanDerWaalsContact CZ-O 3.23Å; R447-W503 PolarHBondContact NE-O 2.7Å; R447-W503 PolarHBondContact NH2-O 3.18Å; C448-W503 VanDerWaalsContact SG-C 3.52Å; C448-W503 PolarHBondContact SG-O 3.21Å; F474-W503 AromaticContact CD2-CH2 3.8Å; F474-W503 HydrophobicContact CD2-CH2 3.8Å; F474-W503 HydrophobicContact CD2-CZ3 4.06Å; F474-W503 AromaticContact CE2-CH2 3.76Å; F474-W503 HydrophobicContact CE2-CH2 3.76Å; F474-W503 HydrophobicContact CE2-CZ2 4.44Å; F474-W503 AromaticContact CE2-CZ3 3.93Å; F474-W503 HydrophobicContact CE2-CZ3 3.93Å; E477-W503 HydrophobicContact CG-CH2 4.28Å; E477-W503 HydrophobicContact CG-CZ2 4.14Å; W478-W503 HydrophobicContact CH2-CZ2 4.48Å; W478-W503 AromaticContact CZ2-CE2 3.95Å; W478-W503 AromaticContact CZ2-CZ2 3.62Å; W478-W503 HydrophobicContact CZ2-CZ2 3.62Å; W478-W503 AromaticContact CZ2-NE1 3.9Å; T500-W503 HydrophobicContact CG2-CD2 4.04Å; T500-W503 HydrophobicContact CG2-CE3 4.34Å; T500-W503 HydrophobicContact CG2-CZ2 4.28Å; T500-W503 WeakPolarHBondContact O-CB 3.44Å; T500-W503 PolarHBondContact O-N 3.46Å; W503-E507 HydrophobicContact CB-CB 4.12Å; W503-E507 HydrophobicContact CB-CG 4.3Å; W503-E507 HydrophobicContact CD2-CB 3.6Å; W503-E507 HydrophobicContact CD2-CG 4.18Å; W503-E507 HydrophobicContact CE3-CB 3.76Å; W503-E507 HydrophobicContact CG-CB 3.79Å; W503-E507 HydrophobicContact CG-CG 3.94Å; W503-E507 HydrophobicContact CZ3-CB 4.3Å; W503-L511 HydrophobicContact CZ3-CD2 4.02Å
504	G	91.7	Very high	95.5	Very high	11 Å²	11	46.4 Å²	46.4	11%	0.113	25%	0.25	C	C	.	.			trans	-133.1	-135.8	176	0	0	0	0	0	111.7	C448 E507 V508	C448-G504 PolarHBondContact SG-O 3.38Å; G504-E507 PolarHBondContact N-OE2 3.39Å; G504-V508 VanDerWaalsContact O-CG2 3.31Å; G504-V508 WeakPolarHBondContact O-CG2 3.49Å
505	N	93	Very high	95.5	Very high	76 Å²	76	45.2 Å²	45.2	41%	0.406	24%	0.243	S	C	.	.	H	α-helix	trans	-81.5	-22.5	-178.9	-68.4	-60.3	0	0	0	113.7	R451 G509	R451-N505 WeakPolarHBondContact CB-OD1 3.37Å; R451-N505 WeakPolarHBondContact CG-OD1 3.4Å; N505-G509 PolarHBondContact O-N 3.36Å; N505-G509 VanDerWaalsContact O-N 3.14Å
506	E	93.4	Very high	95.3	Very high	150 Å²	150	50.5 Å²	50.5	70%	0.701	26%	0.264	S	S	*	.	H	α-helix	trans	-77.4	-51.9	-175.9	-174.1	170	166.2	0	0	111.3	V508 G509 L510	E506-V508 VanDerWaalsContact C-N 3.32Å; E506-V508 PolarHBondContact O-N 3.24Å; E506-G509 CarbonylContact O-C 3.43Å; E506-G509 WeakPolarHBondContact O-CA 3.29Å; E506-G509 PolarHBondContact O-N 3Å; E506-L510 HydrophobicContact CG-CD1 4.43Å; E506-L510 WeakPolarHBondContact O-CG 3.37Å; E506-L510 PolarHBondContact O-N 3.33Å
507	E	96.9	Very high	95.3	Very high	66 Å²	66	53.1 Å²	53.1	31%	0.308	27%	0.272	S	S	.	.	H	α-helix	trans	-63.3	-38.4	179.6	-56.5	85.7	164	0	0	111.4	W503 G504 G509 L510 L511	W503-E507 HydrophobicContact CB-CB 4.12Å; W503-E507 HydrophobicContact CB-CG 4.3Å; W503-E507 HydrophobicContact CD2-CB 3.6Å; W503-E507 HydrophobicContact CD2-CG 4.18Å; W503-E507 HydrophobicContact CE3-CB 3.76Å; W503-E507 HydrophobicContact CG-CB 3.79Å; W503-E507 HydrophobicContact CG-CG 3.94Å; W503-E507 HydrophobicContact CZ3-CB 4.3Å; G504-E507 PolarHBondContact N-OE2 3.39Å; E507-G509 VanDerWaalsContact C-N 3.31Å; E507-G509 PolarHBondContact O-N 3.45Å; E507-L510 PolarHBondContact O-N 2.98Å; E507-L511 VanDerWaalsContact O-CB 3.24Å; E507-L511 WeakPolarHBondContact O-CB 3.21Å; E507-L511 PolarHBondContact O-N 3.44Å
508	V	97.8	Very high	95.3	Very high	0 Å²	0	49.6 Å²	49.6	0%	0	25%	0.253	C	S	.	.	H	α-helix	trans	-67.2	-34	172.4	179.3	0	0	0	0	111.3	C448 R451 L452 G504 E506 L512	C448-V508 HydrophobicContact CB-CG2 3.55Å; R451-V508 HydrophobicContact CB-CG1 4.28Å; R451-V508 HydrophobicContact CG-CB 4.01Å; R451-V508 HydrophobicContact CG-CG1 3.72Å; L452-V508 HydrophobicContact CB-CG1 4.01Å; L452-V508 HydrophobicContact CD1-CG1 4.49Å; G504-V508 VanDerWaalsContact O-CG2 3.31Å; G504-V508 WeakPolarHBondContact O-CG2 3.49Å; E506-V508 VanDerWaalsContact C-N 3.32Å; E506-V508 PolarHBondContact O-N 3.24Å; V508-L512 HydrophobicContact CG1-CD1 4.03Å; V508-L512 HydrophobicContact CG1-CG 4.48Å; V508-L512 VanDerWaalsContact O-CB 3.28Å; V508-L512 WeakPolarHBondContact O-CB 3.37Å; V508-L512 WeakPolarHBondContact O-CD1 3.33Å; V508-L512 WeakPolarHBondContact O-CG 3.46Å; V508-L512 PolarHBondContact O-N 3.42Å
509	G	96.6	Very high	95.2	Very high	23 Å²	23	50.2 Å²	50.2	24%	0.237	26%	0.256	C	S	.	.	H	α-helix	trans	-64.6	-44.7	173	0	0	0	0	0	112.9	N505 E506 E507 L512 A513	N505-G509 PolarHBondContact O-N 3.36Å; N505-G509 VanDerWaalsContact O-N 3.14Å; E506-G509 CarbonylContact O-C 3.43Å; E506-G509 WeakPolarHBondContact O-CA 3.29Å; E506-G509 PolarHBondContact O-N 3Å; E507-G509 VanDerWaalsContact C-N 3.31Å; E507-G509 PolarHBondContact O-N 3.45Å; G509-L512 PolarHBondContact O-N 3.45Å; G509-A513 PolarHBondContact O-N 3.42Å
510	L	97.4	Very high	95	Very high	100 Å²	100	55.9 Å²	55.9	52%	0.524	27%	0.269	S	S	.	.	H	α-helix	trans	-65.3	-47.2	176	-66.9	171.9	0	0	0	111.5	E506 E507 L512 A513 E514	E506-L510 HydrophobicContact CG-CD1 4.43Å; E506-L510 WeakPolarHBondContact O-CG 3.37Å; E506-L510 PolarHBondContact O-N 3.33Å; E507-L510 PolarHBondContact O-N 2.98Å; L510-L512 VanDerWaalsContact C-N 3.28Å; L510-L512 PolarHBondContact O-N 2.95Å; L510-A513 PolarHBondContact O-N 3.33Å; L510-A513 VanDerWaalsContact O-N 3.16Å; L510-E514 PolarHBondContact O-N 3.4Å
511	L	98.5	Very high	94.7	Very high	7 Å²	7	60.9 Å²	60.9	4%	0.037	29%	0.294	C	S	.	.	H	α-helix	trans	-54.9	-43.2	174.5	172.3	61.6	0	0	0	111.9	V470 A473 F474 W503 E507 A515	V470-L511 HydrophobicContact CG1-CD1 4.39Å; V470-L511 HydrophobicContact CG1-CD2 3.93Å; V470-L511 HydrophobicContact CG1-CG 4.12Å; A473-L511 HydrophobicContact CB-CD1 3.59Å; F474-L511 HydrophobicContact CB-CD1 3.81Å; F474-L511 HydrophobicContact CB-CD2 4.38Å; F474-L511 HydrophobicContact CD2-CD2 4.13Å; F474-L511 VanDerWaalsContact N-CD1 3.27Å; W503-L511 HydrophobicContact CZ3-CD2 4.02Å; E507-L511 VanDerWaalsContact O-CB 3.24Å; E507-L511 WeakPolarHBondContact O-CB 3.21Å; E507-L511 PolarHBondContact O-N 3.44Å; L511-A515 VanDerWaalsContact O-CB 3.26Å; L511-A515 WeakPolarHBondContact O-CB 3.23Å; L511-A515 PolarHBondContact O-N 3.47Å
512	L	98	Very high	94.6	Very high	0 Å²	0	60.2 Å²	60.2	0%	0	29%	0.289	C	S	.	.	H	α-helix	trans	-68	-39.6	177.7	-81	169.6	0	0	0	113	W234 L452 T455 F466 V470 V508 G509 L510 A515 Y516	W234-L512 HydrophobicContact CH2-CB 4.24Å; L452-L512 HydrophobicContact CD1-CD1 4.43Å; L452-L512 HydrophobicContact CD1-CD2 3.71Å; L452-L512 HydrophobicContact CD1-CG 4.11Å; T455-L512 HydrophobicContact CG2-CD1 4.1Å; T455-L512 HydrophobicContact CG2-CD2 3.79Å; T455-L512 WeakPolarHBondContact OG1-CD1 3.43Å; F466-L512 HydrophobicContact CE1-CD2 3.54Å; F466-L512 HydrophobicContact CZ-CD2 3.78Å; V470-L512 HydrophobicContact CG2-CD2 4.22Å; V508-L512 HydrophobicContact CG1-CD1 4.03Å; V508-L512 HydrophobicContact CG1-CG 4.48Å; V508-L512 VanDerWaalsContact O-CB 3.28Å; V508-L512 WeakPolarHBondContact O-CB 3.37Å; V508-L512 WeakPolarHBondContact O-CD1 3.33Å; V508-L512 WeakPolarHBondContact O-CG 3.46Å; V508-L512 PolarHBondContact O-N 3.42Å; G509-L512 PolarHBondContact O-N 3.45Å; L510-L512 VanDerWaalsContact C-N 3.28Å; L510-L512 PolarHBondContact O-N 2.95Å; L512-A515 PolarHBondContact O-N 3.49Å; L512-Y516 WeakPolarHBondContact O-CB 3.19Å; L512-Y516 PolarHBondContact O-N 3.12Å
513	A	96.9	Very high	93.9	Very high	54 Å²	54	56 Å²	56	45%	0.446	28%	0.279	S	S	.	.	H	α-helix	trans	-64.9	-43.1	176.6	0	0	0	0	0	111.4	G509 L510 Y516 R517	G509-A513 PolarHBondContact O-N 3.42Å; L510-A513 PolarHBondContact O-N 3.33Å; L510-A513 VanDerWaalsContact O-N 3.16Å; A513-Y516 PolarHBondContact O-N 3.42Å; A513-R517 PolarHBondContact O-N 3.09Å
514	E	97.6	Very high	92.4	Very high	47 Å²	47	62.4 Å²	62.4	22%	0.22	31%	0.314	C	S	.	.	H	α-helix	trans	-65.5	-44.2	174.8	176.8	58.1	-166.7	0	0	111.6	A473 L510 Y516 R517 L518	A473-E514 HydrophobicContact CB-CB 4.15Å; A473-E514 HydrophobicContact CB-CG 3.72Å; L510-E514 PolarHBondContact O-N 3.4Å; E514-Y516 VanDerWaalsContact C-N 3.28Å; E514-Y516 PolarHBondContact O-N 3.36Å; E514-R517 WeakPolarHBondContact O-CB 3.29Å; E514-R517 PolarHBondContact O-N 3.15Å; E514-R517 VanDerWaalsContact O-N 3.17Å; E514-R517 IonicContact OE1-CZ 2.77Å; E514-R517 IonicContact OE1-NE 3.13Å; E514-R517 IonicContact OE1-NH2 3.37Å; E514-R517 PolarHBondContact OE1-NH2 3.1Å; E514-R517 IonicContact OE2-CZ 3.89Å; E514-R517 IonicContact OE2-NE 2.72Å; E514-R517 PolarHBondContact OE2-NE 3.03Å; E514-R517 IonicContact OE2-NH2 2.91Å; E514-R517 PolarHBondContact OE2-NH2 3.34Å; E514-L518 HydrophobicContact CG-CD1 4.37Å; E514-L518 WeakPolarHBondContact O-CG 3.36Å; E514-L518 PolarHBondContact O-N 3.01Å
515	A	97.4	Very high	90.6	Very high	0 Å²	0	63.3 Å²	63.3	0%	0	32%	0.321	C	S	.	.	H	α-helix	trans	-57.9	-39.5	173.8	0	0	0	0	0	112.5	F466 Y469 V470 A473 L511 L512 L518 K519	F466-A515 HydrophobicContact CE2-CB 3.81Å; F466-A515 HydrophobicContact CZ-CB 4Å; Y469-A515 WeakPolarHBondContact CB-O 3.28Å; V470-A515 HydrophobicContact CB-CB 4.27Å; V470-A515 HydrophobicContact CG2-CB 3.63Å; A473-A515 HydrophobicContact CB-CB 4.07Å; L511-A515 VanDerWaalsContact O-CB 3.26Å; L511-A515 WeakPolarHBondContact O-CB 3.23Å; L511-A515 PolarHBondContact O-N 3.47Å; L512-A515 PolarHBondContact O-N 3.49Å; A515-L518 PolarHBondContact O-N 3.36Å; A515-K519 WeakPolarHBondContact O-CB 3.41Å; A515-K519 PolarHBondContact O-N 3.1Å
516	Y	95.2	Very high	88.4	Confident	111 Å²	111	63 Å²	63	44%	0.435	32%	0.323	S	S	.	.	H	α-helix	trans	-69.6	-39.6	176.3	-171.5	-94.3	0	0	0	112.2	W234 L512 A513 E514 L518 K519 Y520	W234-Y516 HydrophobicContact CH2-CD2 4.29Å; W234-Y516 HydrophobicContact CH2-CG 4.18Å; W234-Y516 AromaticContact CZ2-CD2 3.68Å; W234-Y516 HydrophobicContact CZ2-CD2 3.68Å; W234-Y516 HydrophobicContact CZ2-CG 4.02Å; L512-Y516 WeakPolarHBondContact O-CB 3.19Å; L512-Y516 PolarHBondContact O-N 3.12Å; A513-Y516 PolarHBondContact O-N 3.42Å; E514-Y516 VanDerWaalsContact C-N 3.28Å; E514-Y516 PolarHBondContact O-N 3.36Å; Y516-L518 VanDerWaalsContact C-N 3.34Å; Y516-L518 PolarHBondContact O-N 3.11Å; Y516-K519 WeakPolarHBondContact O-CB 3.34Å; Y516-K519 PolarHBondContact O-N 3.01Å; Y516-Y520 PolarHBondContact O-N 2.75Å
517	R	95.6	Very high	86.3	Confident	106 Å²	106	61.5 Å²	61.5	40%	0.4	32%	0.32	S	S	.	.	H	α-helix	trans	-59	-44.8	171.9	-170	-169	70.5	82	-2.3	111.4	A513 E514 Y520 M521	A513-R517 PolarHBondContact O-N 3.09Å; E514-R517 WeakPolarHBondContact O-CB 3.29Å; E514-R517 PolarHBondContact O-N 3.15Å; E514-R517 VanDerWaalsContact O-N 3.17Å; E514-R517 IonicContact OE1-CZ 2.77Å; E514-R517 IonicContact OE1-NE 3.13Å; E514-R517 IonicContact OE1-NH2 3.37Å; E514-R517 PolarHBondContact OE1-NH2 3.1Å; E514-R517 IonicContact OE2-CZ 3.89Å; E514-R517 IonicContact OE2-NE 2.72Å; E514-R517 PolarHBondContact OE2-NE 3.03Å; E514-R517 IonicContact OE2-NH2 2.91Å; E514-R517 PolarHBondContact OE2-NH2 3.34Å; R517-Y520 PolarHBondContact O-N 3.31Å; R517-M521 HydrophobicContact CG-SD 4.34Å; R517-M521 PolarHBondContact NH1-SD 3.31Å; R517-M521 WeakPolarHBondContact O-CB 3.17Å; R517-M521 WeakPolarHBondContact O-CG 3.49Å; R517-M521 PolarHBondContact O-N 3.06Å
518	L	95.2	Very high	83.8	Confident	0 Å²	0	65.8 Å²	65.8	0%	0	34%	0.339	C	S	.	.	H	α-helix	trans	-65.9	-41	176.2	-66.4	177	0	0	0	111.9	I413 Y469 A472 A473 I476 E514 A515 Y516 M521 F522	I413-L518 HydrophobicContact CD1-CD1 4.1Å; I413-L518 HydrophobicContact CD1-CD2 3.86Å; I413-L518 HydrophobicContact CD1-CG 4.43Å; I413-L518 HydrophobicContact CG1-CD2 4.17Å; I413-L518 HydrophobicContact CG2-CD2 3.95Å; Y469-L518 HydrophobicContact CD1-CB 4.09Å; A472-L518 HydrophobicContact CB-CD1 4.26Å; A473-L518 HydrophobicContact CB-CD1 3.97Å; I476-L518 HydrophobicContact CD1-CD1 3.86Å; E514-L518 HydrophobicContact CG-CD1 4.37Å; E514-L518 WeakPolarHBondContact O-CG 3.36Å; E514-L518 PolarHBondContact O-N 3.01Å; A515-L518 PolarHBondContact O-N 3.36Å; Y516-L518 VanDerWaalsContact C-N 3.34Å; Y516-L518 PolarHBondContact O-N 3.11Å; L518-M521 PolarHBondContact O-N 3.02Å; L518-F522 HydrophobicContact CD2-CD2 4.35Å; L518-F522 HydrophobicContact CD2-CE2 4.15Å; L518-F522 WeakPolarHBondContact O-CB 3.34Å; L518-F522 WeakPolarHBondContact O-CD2 3.49Å; L518-F522 PolarHBondContact O-N 2.82Å
519	K	93.8	Very high	81.1	Confident	20 Å²	20	75.6 Å²	75.6	9%	0.087	38%	0.378	C	S	.	.	H	α-helix	trans	-54.9	-55.4	172.5	-173.4	-165.9	179	-168.1	0	110.4	E459 E461 F466 Y469 A515 Y516 M521 F522 A523	E459-K519 IonicContact OE1-NZ 3.17Å; E459-K519 PolarHBondContact OE1-NZ 3.4Å; E461-K519 IonicContact OE1-NZ 2.67Å; E461-K519 WeakPolarHBondContact OE2-CE 3.27Å; E461-K519 IonicContact OE2-NZ 3.97Å; E461-K519 PolarHBondContact OE2-NZ 3.28Å; F466-K519 HydrophobicContact CD2-CD 4.17Å; Y469-K519 HydrophobicContact CD1-CB 4.2Å; Y469-K519 HydrophobicContact CD2-CB 3.96Å; Y469-K519 HydrophobicContact CD2-CG 4.07Å; Y469-K519 HydrophobicContact CE1-CB 4.46Å; Y469-K519 HydrophobicContact CE2-CB 4.24Å; Y469-K519 HydrophobicContact CE2-CG 3.98Å; Y469-K519 HydrophobicContact CG-CB 3.94Å; A515-K519 WeakPolarHBondContact O-CB 3.41Å; A515-K519 PolarHBondContact O-N 3.1Å; Y516-K519 WeakPolarHBondContact O-CB 3.34Å; Y516-K519 PolarHBondContact O-N 3.01Å; K519-M521 VanDerWaalsContact C-N 3.35Å; K519-M521 PolarHBondContact O-N 3.44Å; K519-F522 PolarHBondContact O-N 3.4Å; K519-A523 WeakPolarHBondContact O-CB 3.3Å; K519-A523 PolarHBondContact O-N 3.31Å
520	Y	90.6	Very high	78.5	Confident	189 Å²	189	81 Å²	81	74%	0.741	40%	0.395	S	S	*	.	H	α-helix	trans	-62.4	-38.1	-177.5	-169.1	-94.1	0	0	0	113.1	Y516 R517	Y516-Y520 PolarHBondContact O-N 2.75Å; R517-Y520 PolarHBondContact O-N 3.31Å
521	M	90.4	Very high	75.4	Confident	106 Å²	106	91.3 Å²	91.3	52%	0.522	43%	0.427	S	S	.	.	H	α-helix	trans	-77.4	-23.2	-179.9	-75.2	-173.2	61.9	0	0	114.9	R517 L518 K519	R517-M521 HydrophobicContact CG-SD 4.34Å; R517-M521 PolarHBondContact NH1-SD 3.31Å; R517-M521 WeakPolarHBondContact O-CB 3.17Å; R517-M521 WeakPolarHBondContact O-CG 3.49Å; R517-M521 PolarHBondContact O-N 3.06Å; L518-M521 PolarHBondContact O-N 3.02Å; K519-M521 VanDerWaalsContact C-N 3.35Å; K519-M521 PolarHBondContact O-N 3.44Å
522	F	86.4	Confident	74.2	Confident	37 Å²	37	95.6 Å²	95.6	16%	0.162	45%	0.447	C	S	.	.	H	α-helix	trans	-124	-3.4	-170	-68.6	-87.1	0	0	0	115.8	L409 R412 I413 Y469 L518 K519 A525	L409-F522 HydrophobicContact CD1-CB 3.98Å; L409-F522 HydrophobicContact CD1-CG 4.32Å; R412-F522 HydrophobicContact CB-CD1 4.44Å; R412-F522 HydrophobicContact CB-CE1 4.16Å; I413-F522 HydrophobicContact CB-CZ 4.44Å; I413-F522 HydrophobicContact CG1-CD1 4.49Å; I413-F522 HydrophobicContact CG1-CD2 4.05Å; I413-F522 HydrophobicContact CG1-CE1 4.14Å; I413-F522 HydrophobicContact CG1-CE2 3.68Å; I413-F522 HydrophobicContact CG1-CG 4.45Å; I413-F522 HydrophobicContact CG1-CZ 3.72Å; Y469-F522 HydrophobicContact CE1-CB 4.42Å; L518-F522 HydrophobicContact CD2-CD2 4.35Å; L518-F522 HydrophobicContact CD2-CE2 4.15Å; L518-F522 WeakPolarHBondContact O-CB 3.34Å; L518-F522 WeakPolarHBondContact O-CD2 3.49Å; L518-F522 PolarHBondContact O-N 2.82Å; K519-F522 PolarHBondContact O-N 3.4Å; F522-A525 HydrophobicContact CD1-CB 4.4Å
523	A	74.9	Confident	73	Confident	52 Å²	52	100.6 Å²	100.6	43%	0.43	47%	0.47	S	S	.	.	S	Bend	trans	-63.2	-50.9	175.9	0	0	0	0	0	112.7	K519	K519-A523 WeakPolarHBondContact O-CB 3.3Å; K519-A523 PolarHBondContact O-N 3.31Å
524	D	62.7	Low	71.7	Confident	155 Å²	155	103.2 Å²	103.2	83%	0.829	47%	0.471	S	S	*	.	S	Bend	trans	-87.7	-0.3	-179.9	-70.6	-47.6	0	0	0	113.9	P526	D524-P526 WeakPolarHBondContact O-CD 3.4Å; D524-P526 VanDerWaalsContact O-N 3.14Å
525	A	53.8	Low	70.1	Confident	31 Å²	31	106.5 Å²	106.5	26%	0.256	49%	0.486	S	S	.	.			trans	-69.9	107.9	-172.1	0	0	0	0	0	111.6	R412 F522	R412-A525 PolarHBondContact NH1-O 3.28Å; F522-A525 HydrophobicContact CD1-CB 4.4Å
526	P	47	Very low	68.4	Low	70 Å²	70	113.1 Å²	113.1	46%	0.455	52%	0.517	S	S	.	.			trans	-72.1	157.4	-173.4	31.9	-36.3	0	0	0	111.5	D524 H528	D524-P526 WeakPolarHBondContact O-CD 3.4Å; D524-P526 VanDerWaalsContact O-N 3.14Å; P526-H528 PolarHBondContact O-N 3.11Å
527	N	49.8	Very low	66.7	Low	117 Å²	117	113.3 Å²	113.3	63%	0.626	52%	0.522	S	S	*	.	T	Hydrogen-bonded Turn	trans	-65.6	16.4	-176.2	-71	-25.4	0	0	0	115.7
528	H	44.4	Very low	64.6	Low	156 Å²	156	113.8 Å²	113.8	72%	0.722	53%	0.531	S	S	*	.	T	Hydrogen-bonded Turn	trans	-84.5	-9.7	-176.4	-61	-45.3	0	0	0	114.4	P526 K530	P526-H528 PolarHBondContact O-N 3.11Å; H528-K530 PolarHBondContact O-N 2.99Å; H528-K530 VanDerWaalsContact O-N 3.15Å
529	Y	40.4	Very low	62.2	Low	206 Å²	206	122.5 Å²	122.5	81%	0.808	57%	0.571	S	S	*	*			trans	-85.8	42.5	173.1	-72.7	-77.6	0	0	0	113.3
530	K	41.5	Very low	59.6	Low	136 Å²	136	131.1 Å²	131.1	59%	0.591	61%	0.612	S	S	*	*			trans	-117.8	105.1	162.1	-73.5	176.2	-177.2	170.5	0	107.7	E408 H528	E408-K530 IonicContact OE1-NZ 3.62Å; E408-K530 PolarHBondContact OE1-NZ 3.46Å; H528-K530 PolarHBondContact O-N 2.99Å; H528-K530 VanDerWaalsContact O-N 3.15Å
531	R	33.3	Very low	56.8	Low	318 Å²	318	125.8 Å²	125.8	100%	1.2	60%	0.6	S	S	*	*			trans	-133.3	0	173.8	-93.2	-168.9	170.9	-165.3	-2.1	108.6

Retrieved 531 of 531 residues in 872.4 ms (Link to these results)

U.S. Privacy Notice - Disclaimer / Registrations / Copyright Statement - Linking Policy - Notice of Privacy Practices (HIPAA) - Notice of Non‑Discrimination
© Copyright 2026 St. Jude Children's Research Hospital, a not-for-profit, section 501(c)(3).