A0A096MF53_POEFO Loading...

Tubulin tyrosine ligase-like family, member 7

AlphaFold DB , UniProt , Accession A0A096MF53, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 407 aa.

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Site Residue pLDDT pLDDT confidence pLDDT10 pLDDT10 confidence SASA SASA [Ų] SASA10 SASA10 [Ų] RSA RSA unformatted RSA10 RSA10 unformatted Surface Surface10 (not used) Disorder (not used) Disorder Sec. str. Secondary structure Isomer Phi (φ) Psi (ψ) Omega (ω) Chi 1 (χ1) Chi 2 (χ2) Chi 3 (χ3) Chi 4 (χ4) Chi 5 (χ5) Tau (τ) Contacts (colored by PAE) Contact details
1M90.9Very high93.1Very high33 Ų3378.2 Ų78.216%0.16338%0.379CS..  0-67.60-57.7-44.2-75.300113.8R3 C4 Q5 Y9 V189 A359 A360M1-R3 VanDerWaalsContact C-N 3.29Å; M1-R3 PolarHBondContact O-N 2.94Å; M1-R3 VanDerWaalsContact O-N 3.14Å; M1-C4 PolarHBondContact O-N 3.48Å; M1-Q5 PolarHBondContact O-N 3.09Å; M1-Y9 HydrophobicContact CB-CD1 4.23Å; M1-Y9 HydrophobicContact CB-CD2 4.06Å; M1-Y9 HydrophobicContact CB-CE1 4.24Å; M1-Y9 HydrophobicContact CB-CE2 4.08Å; M1-Y9 HydrophobicContact CB-CG 4.14Å; M1-Y9 HydrophobicContact CE-CE2 3.61Å; M1-Y9 WeakPolarHBondContact CE-OH 3.36Å; M1-V189 HydrophobicContact CB-CG2 4.28Å; M1-V189 HydrophobicContact CG-CB 4.31Å; M1-V189 HydrophobicContact CG-CG1 3.82Å; M1-V189 HydrophobicContact CG-CG2 3.74Å; M1-A359 HydrophobicContact CE-CB 4.36Å; M1-A360 HydrophobicContact CE-CB 3.96Å; M1-A360 HydrophobicContact SD-CB 4.07Å
2I92.6Very high93.3Very high93 Ų9375.3 Ų75.348%0.47737%0.37SS..THydrogen-bonded Turntrans-51.4-42.3-177.8-60.6173.9000113.6C4 P6 T12I2-C4 VanDerWaalsContact C-N 3.32Å; I2-C4 PolarHBondContact O-N 3.05Å; I2-P6 WeakPolarHBondContact O-CA 3.49Å; I2-P6 WeakPolarHBondContact O-CB 3.35Å; I2-T12 WeakPolarHBondContact CD1-OG1 3.44Å
3R89.1Confident93.4Very high231 Ų23170 Ų7087%0.87234%0.344SS*.THydrogen-bonded Turntrans-66.4-31.3177.7-65.3-175.3-172.8170.84.2113.8M1M1-R3 VanDerWaalsContact C-N 3.29Å; M1-R3 PolarHBondContact O-N 2.94Å; M1-R3 VanDerWaalsContact O-N 3.14Å
4C89.5Confident93.5Very high73 Ų7375.4 Ų75.449%0.49336%0.359SS..THydrogen-bonded Turntrans-89.9-33.4-176.5-53.60000111.9M1 I2M1-C4 PolarHBondContact O-N 3.48Å; I2-C4 VanDerWaalsContact C-N 3.32Å; I2-C4 PolarHBondContact O-N 3.05Å
5Q92.8Very high93.7Very high62 Ų6274.1 Ų74.129%0.2936%0.358SS..  trans-13763.5-173-65-64-10.600110.4M1 H7 E8 Y9 L356M1-Q5 PolarHBondContact O-N 3.09Å; Q5-H7 VanDerWaalsContact C-N 3.33Å; Q5-H7 PolarHBondContact O-N 3.28Å; Q5-E8 HydrophobicContact CB-CB 4.26Å; Q5-E8 PolarHBondContact O-N 3.32Å; Q5-Y9 HydrophobicContact CB-CD2 3.78Å; Q5-Y9 HydrophobicContact CB-CE2 4.01Å; Q5-Y9 WeakPolarHBondContact O-CD2 3.22Å; Q5-Y9 PolarHBondContact O-N 3.39Å; Q5-Y9 VanDerWaalsContact O-N 3.13Å; Q5-L356 HydrophobicContact CB-CD2 4.34Å; Q5-L356 HydrophobicContact CG-CD2 3.9Å
6P93.1Very high93.7Very high67 Ų6770.9 Ų70.944%0.43534%0.341SS..THydrogen-bonded Turntrans-66.3-32.1-170.525.3-34.5000113.6I2 E8I2-P6 WeakPolarHBondContact O-CA 3.49Å; I2-P6 WeakPolarHBondContact O-CB 3.35Å; P6-E8 VanDerWaalsContact C-N 3.33Å
7H92.9Very high93.8Very high159 Ų15972.5 Ų72.574%0.73635%0.351SS*.THydrogen-bonded Turntrans-71.6-30.2179.1-62.6-69.4000112.2Q5 N10Q5-H7 VanDerWaalsContact C-N 3.33Å; Q5-H7 PolarHBondContact O-N 3.28Å; H7-N10 PolarHBondContact O-ND2 2.89Å
8E95.2Very high93.7Very high41 Ų4168.7 Ų68.719%0.19233%0.332CS..THydrogen-bonded Turntrans-86-34.8-177.5-63.5-62.5157.200112.7Q5 P6 F11 K185 K352 L356Q5-E8 HydrophobicContact CB-CB 4.26Å; Q5-E8 PolarHBondContact O-N 3.32Å; P6-E8 VanDerWaalsContact C-N 3.33Å; E8-F11 WeakPolarHBondContact O-CD1 3.41Å; E8-F11 VanDerWaalsContact O-CE1 3.29Å; E8-F11 WeakPolarHBondContact O-CE1 3.42Å; E8-K185 VanDerWaalsContact OE2-CE 3.28Å; E8-K185 WeakPolarHBondContact OE2-CE 3.31Å; E8-K185 IonicContact OE2-NZ 3.35Å; E8-K185 PolarHBondContact OE2-NZ 2.92Å; E8-K352 WeakPolarHBondContact OE1-CE 3.35Å; E8-K352 IonicContact OE1-NZ 3.09Å; E8-K352 PolarHBondContact OE1-NZ 3.28Å; E8-K352 WeakPolarHBondContact OE2-CE 3.25Å; E8-K352 IonicContact OE2-NZ 2.72Å; E8-K352 PolarHBondContact OE2-NZ 2.85Å; E8-L356 HydrophobicContact CB-CD1 4.39Å; E8-L356 HydrophobicContact CB-CD2 4.3Å; E8-L356 HydrophobicContact CG-CD1 4.45Å; E8-L356 HydrophobicContact CG-CD2 4.14Å
9Y96.1Very high93.6Very high11 Ų1167.6 Ų67.64%0.04333%0.331CS..SBendtrans-10654.8-177.8-66.8-90000111.8M1 Q5 F11 K185 V189 L356M1-Y9 HydrophobicContact CB-CD1 4.23Å; M1-Y9 HydrophobicContact CB-CD2 4.06Å; M1-Y9 HydrophobicContact CB-CE1 4.24Å; M1-Y9 HydrophobicContact CB-CE2 4.08Å; M1-Y9 HydrophobicContact CB-CG 4.14Å; M1-Y9 HydrophobicContact CE-CE2 3.61Å; M1-Y9 WeakPolarHBondContact CE-OH 3.36Å; Q5-Y9 HydrophobicContact CB-CD2 3.78Å; Q5-Y9 HydrophobicContact CB-CE2 4.01Å; Q5-Y9 WeakPolarHBondContact O-CD2 3.22Å; Q5-Y9 PolarHBondContact O-N 3.39Å; Q5-Y9 VanDerWaalsContact O-N 3.13Å; Y9-F11 AromaticContact CD1-CE1 3.92Å; Y9-F11 HydrophobicContact CD1-CE1 3.92Å; Y9-F11 AromaticContact CD1-CZ 3.66Å; Y9-F11 HydrophobicContact CD1-CZ 3.66Å; Y9-F11 HydrophobicContact CE1-CZ 4.12Å; Y9-F11 HydrophobicContact CG-CE1 4.43Å; Y9-K185 HydrophobicContact CE1-CB 3.95Å; Y9-K185 WeakPolarHBondContact CE1-O 3.48Å; Y9-K185 PolarHBondContact OH-O 2.93Å; Y9-V189 HydrophobicContact CD1-CG2 4.2Å; Y9-V189 HydrophobicContact CE1-CG2 3.34Å; Y9-L356 HydrophobicContact CE2-CD2 4.16Å
10N95.2Very high93.6Very high77 Ų7768 Ų6841%0.41235%0.346SS..  trans-101.58.9179.873.338.9000113.6H7 K228 W230H7-N10 PolarHBondContact O-ND2 2.89Å; N10-K228 PolarHBondContact O-NZ 3.24Å; N10-K228 VanDerWaalsContact OD1-CE 3.22Å; N10-K228 WeakPolarHBondContact OD1-CE 3.47Å; N10-K228 PolarHBondContact OD1-NZ 3.36Å; N10-W230 WeakPolarHBondContact O-CZ3 3.29Å
11F96.6Very high93.6Very high13 Ų1367.2 Ų67.26%0.05734%0.341CS..SBendtrans-100.37.3-174.556.8-101.1000113.7E8 Y9 L182 K185 T186 W230 L231E8-F11 WeakPolarHBondContact O-CD1 3.41Å; E8-F11 VanDerWaalsContact O-CE1 3.29Å; E8-F11 WeakPolarHBondContact O-CE1 3.42Å; Y9-F11 AromaticContact CD1-CE1 3.92Å; Y9-F11 HydrophobicContact CD1-CE1 3.92Å; Y9-F11 AromaticContact CD1-CZ 3.66Å; Y9-F11 HydrophobicContact CD1-CZ 3.66Å; Y9-F11 HydrophobicContact CE1-CZ 4.12Å; Y9-F11 HydrophobicContact CG-CE1 4.43Å; F11-L182 HydrophobicContact CB-CD1 4.01Å; F11-L182 HydrophobicContact CB-CG 4.34Å; F11-L182 HydrophobicContact CD2-CD1 4.04Å; F11-L182 HydrophobicContact CD2-CG 3.65Å; F11-L182 HydrophobicContact CE2-CG 4.08Å; F11-L182 HydrophobicContact CG-CD1 4.2Å; F11-L182 HydrophobicContact CG-CG 3.99Å; F11-K185 HydrophobicContact CE1-CB 3.89Å; F11-K185 HydrophobicContact CE1-CD 3.96Å; F11-K185 HydrophobicContact CZ-CB 3.88Å; F11-T186 WeakPolarHBondContact CE2-OG1 3.49Å; F11-W230 CarbonylContact O-C 3.54Å; F11-W230 VanDerWaalsContact O-CA 3.26Å; F11-W230 WeakPolarHBondContact O-CA 3.47Å; F11-L231 HydrophobicContact CD2-CB 4.15Å; F11-L231 HydrophobicContact CE2-CD2 4.45Å; F11-L231 PolarHBondContact O-N 2.87Å
12T95.5Very high93.6Very high44 Ų4468.8 Ų68.827%0.2735%0.345SS..SBendtrans-113.3131.4174.456.80000109.7I2 L231I2-T12 WeakPolarHBondContact CD1-OG1 3.44Å; T12-L231 HydrophobicContact CG2-CB 4.28Å; T12-L231 HydrophobicContact CG2-CD2 4.29Å
13P94.9Very high93.6Very high6 Ų668.6 Ų68.64%0.03935%0.348CS..  trans-60.5147.8173.3-20.332.4000111T15 Q72 L75 W230 L231P13-T15 PolarHBondContact O-N 2.9Å; P13-T15 PolarHBondContact O-OG1 2.79Å; P13-Q72 HydrophobicContact CB-CG 3.68Å; P13-Q72 HydrophobicContact CG-CG 4.39Å; P13-L75 HydrophobicContact CG-CD1 4.1Å; P13-L75 HydrophobicContact CG-CG 4.29Å; P13-W230 HydrophobicContact CG-CE3 4.03Å; P13-L231 WeakPolarHBondContact CD-O 3.2Å
14R95.1Very high93.8Very high146 Ų14662.2 Ų62.255%0.55133%0.328SS*.  trans-58.8128.1175.6-70.9-178.5177.4-164.1-1.5109.1W16 Y28 Q72 E73R14-W16 HydrophobicContact CB-CH2 3.74Å; R14-W16 HydrophobicContact CB-CZ2 4.31Å; R14-W16 HydrophobicContact CB-CZ3 4.08Å; R14-Y28 VanDerWaalsContact NH1-CE2 3.32Å; R14-Q72 CarbonylContact O-C 3.54Å; R14-Q72 WeakPolarHBondContact O-CA 3.32Å; R14-E73 HydrophobicContact CB-CB 4.46Å; R14-E73 HydrophobicContact CB-CG 3.94Å; R14-E73 WeakPolarHBondContact CD-OE1 3.45Å; R14-E73 PolarHBondContact O-N 2.78Å
15T95.4Very high93.9Very high55 Ų5558.7 Ų58.734%0.33731%0.305SS..EExtended strand (participates in β ladder)trans-132138.1-172.9-53.20000108.7P13 I70 V71 Q72P13-T15 PolarHBondContact O-N 2.9Å; P13-T15 PolarHBondContact O-OG1 2.79Å; T15-I70 HydrophobicContact CG2-CB 4.06Å; T15-I70 HydrophobicContact CG2-CD1 4.17Å; T15-V71 CarbonylContact C-O 3.52Å; T15-V71 WeakPolarHBondContact CA-O 3.43Å; T15-Q72 HydrophobicContact CG2-CB 4.3Å; T15-Q72 WeakPolarHBondContact OG1-CG 3.35Å; T15-Q72 PolarHBondContact OG1-NE2 3.26Å
16W94.9Very high93.9Very high24 Ų2457.2 Ų57.29%0.09130%0.298CS..EExtended strand (participates in β ladder)trans-120.3130.6175.1-62.8-93.5000109.5R14 F18 E21 F25 Y28 F41 I70 V71 E73R14-W16 HydrophobicContact CB-CH2 3.74Å; R14-W16 HydrophobicContact CB-CZ2 4.31Å; R14-W16 HydrophobicContact CB-CZ3 4.08Å; W16-F18 HydrophobicContact CB-CD2 4.37Å; W16-F18 HydrophobicContact CB-CE2 4.06Å; W16-E21 VanDerWaalsContact CA-OE2 3.24Å; W16-E21 WeakPolarHBondContact CA-OE2 3.18Å; W16-E21 HydrophobicContact CB-CB 4.21Å; W16-F25 HydrophobicContact CB-CB 4.21Å; W16-F25 HydrophobicContact CD2-CB 4.28Å; W16-F25 AromaticContact CD2-CD2 3.72Å; W16-F25 HydrophobicContact CD2-CD2 3.72Å; W16-F25 HydrophobicContact CD2-CG 4.47Å; W16-F25 AromaticContact CE3-CD2 3.73Å; W16-F25 HydrophobicContact CE3-CD2 3.73Å; W16-F25 HydrophobicContact CE3-CE2 4.24Å; W16-F25 HydrophobicContact CG-CB 3.85Å; W16-F25 HydrophobicContact CG-CD2 4.11Å; W16-F25 HydrophobicContact CG-CG 4.43Å; W16-F25 HydrophobicContact CZ3-CD2 4.19Å; W16-F25 HydrophobicContact CZ3-CE2 4.4Å; W16-Y28 AromaticContact CH2-CD1 3.42Å; W16-Y28 HydrophobicContact CH2-CD1 3.42Å; W16-Y28 VanDerWaalsContact CH2-CD1 3.42Å; W16-Y28 AromaticContact CH2-CE1 3.44Å; W16-Y28 HydrophobicContact CH2-CE1 3.44Å; W16-Y28 VanDerWaalsContact CH2-CE1 3.44Å; W16-Y28 HydrophobicContact CH2-CG 4.24Å; W16-Y28 AromaticContact CZ2-CD1 3.35Å; W16-Y28 HydrophobicContact CZ2-CD1 3.35Å; W16-Y28 HydrophobicContact CZ2-CD2 4.49Å; W16-Y28 AromaticContact CZ2-CE1 3.8Å; W16-Y28 HydrophobicContact CZ2-CE1 3.8Å; W16-Y28 AromaticContact CZ2-CG 3.73Å; W16-Y28 HydrophobicContact CZ2-CG 3.73Å; W16-Y28 HydrophobicContact CZ3-CD1 4.47Å; W16-F41 HydrophobicContact CH2-CE1 4.09Å; W16-F41 HydrophobicContact CZ3-CD1 4.06Å; W16-F41 AromaticContact CZ3-CE1 3.8Å; W16-F41 HydrophobicContact CZ3-CE1 3.8Å; W16-I70 WeakPolarHBondContact O-CA 3.13Å; W16-V71 HydrophobicContact CE3-CG1 4.44Å; W16-V71 PolarHBondContact N-O 3.08Å; W16-V71 PolarHBondContact O-N 2.82Å; W16-E73 HydrophobicContact CH2-CG 3.93Å; W16-E73 HydrophobicContact CZ3-CG 3.87Å
17I94.2Very high93.8Very high98 Ų9858.3 Ų58.350%0.50330%0.3SS..EExtended strand (participates in β ladder)trans-93.1114.4-178.8-56172.8000109.3A20 E21 I70I17-A20 PolarHBondContact O-N 3.19Å; I17-E21 PolarHBondContact N-OE2 3.05Å; I17-E21 WeakPolarHBondContact O-CB 3.49Å; I17-E21 PolarHBondContact O-N 2.99Å; I17-I70 HydrophobicContact CG1-CG2 4.46Å
18F92.1Very high93.8Very high4 Ų452.2 Ų52.22%0.01827%0.271CS..THydrogen-bonded Turntrans-91.9145178.3-81.5-140.8000111.3W16 Y22 F25 L63 F69 V71W16-F18 HydrophobicContact CB-CD2 4.37Å; W16-F18 HydrophobicContact CB-CE2 4.06Å; F18-Y22 HydrophobicContact CD1-CD2 4.01Å; F18-Y22 AromaticContact CE1-CD2 3.39Å; F18-Y22 HydrophobicContact CE1-CD2 3.39Å; F18-Y22 HydrophobicContact CE1-CE2 4.1Å; F18-Y22 HydrophobicContact CE1-CG 4.36Å; F18-Y22 AromaticContact CZ-CD2 3.87Å; F18-Y22 HydrophobicContact CZ-CD2 3.87Å; F18-F25 HydrophobicContact CE2-CB 3.84Å; F18-F25 HydrophobicContact CE2-CD1 4.18Å; F18-F25 HydrophobicContact CE2-CG 4.05Å; F18-F25 HydrophobicContact CZ-CB 4Å; F18-F25 AromaticContact CZ-CD1 3.57Å; F18-F25 HydrophobicContact CZ-CD1 3.57Å; F18-F25 HydrophobicContact CZ-CE1 4.23Å; F18-F25 AromaticContact CZ-CG 3.92Å; F18-F25 HydrophobicContact CZ-CG 3.92Å; F18-L63 HydrophobicContact CE1-CB 4.24Å; F18-L63 HydrophobicContact CE1-CD1 4.12Å; F18-L63 HydrophobicContact CZ-CD1 4.26Å; F18-F69 WeakPolarHBondContact CA-O 3.18Å; F18-F69 HydrophobicContact CB-CD1 4.33Å; F18-F69 HydrophobicContact CB-CD2 4.35Å; F18-F69 HydrophobicContact CB-CE1 4.21Å; F18-F69 HydrophobicContact CB-CE2 4.27Å; F18-F69 HydrophobicContact CB-CG 4.39Å; F18-F69 HydrophobicContact CB-CZ 4.2Å; F18-F69 VanDerWaalsContact CB-O 3.32Å; F18-F69 WeakPolarHBondContact CB-O 3.49Å; F18-F69 HydrophobicContact CD1-CD2 4.46Å; F18-F69 AromaticContact CD1-CE1 3.88Å; F18-F69 HydrophobicContact CD1-CE1 3.88Å; F18-F69 AromaticContact CD1-CE2 3.59Å; F18-F69 HydrophobicContact CD1-CE2 3.59Å; F18-F69 AromaticContact CD1-CZ 3.24Å; F18-F69 HydrophobicContact CD1-CZ 3.24Å; F18-F69 AromaticContact CE1-CE2 3.96Å; F18-F69 HydrophobicContact CE1-CE2 3.96Å; F18-F69 AromaticContact CE1-CZ 3.73Å; F18-F69 HydrophobicContact CE1-CZ 3.73Å; F18-F69 HydrophobicContact CG-CD2 4.4Å; F18-F69 HydrophobicContact CG-CE1 4.42Å; F18-F69 AromaticContact CG-CE2 3.92Å; F18-F69 HydrophobicContact CG-CE2 3.92Å; F18-F69 AromaticContact CG-CZ 3.93Å; F18-F69 HydrophobicContact CG-CZ 3.93Å; F18-F69 PolarHBondContact N-O 2.93Å; F18-V71 HydrophobicContact CD2-CG2 3.98Å; F18-V71 HydrophobicContact CE1-CG2 4.25Å; F18-V71 HydrophobicContact CE2-CB 4.24Å; F18-V71 HydrophobicContact CE2-CG2 3.65Å; F18-V71 HydrophobicContact CG-CG2 4.47Å; F18-V71 HydrophobicContact CZ-CG2 3.79Å
19P92.6Very high93.6Very high47 Ų4750.7 Ų50.731%0.30526%0.264SS..THydrogen-bonded Turncis-84.7-5.82.434.5-38000114.9E21 Y22 S65 H68P19-E21 VanDerWaalsContact C-N 3.28Å; P19-E21 PolarHBondContact O-N 2.83Å; P19-Y22 WeakPolarHBondContact O-CB 3.33Å; P19-Y22 PolarHBondContact O-N 3.46Å; P19-S65 WeakPolarHBondContact CB-O 3.2Å; P19-H68 WeakPolarHBondContact CD-ND1 3.45Å
20A93.1Very high93.4Very high76 Ų7656.5 Ų56.563%0.62829%0.29SS*.THydrogen-bonded Turntrans-60-31.8-169.500000114.9I17I17-A20 PolarHBondContact O-N 3.19Å
21E93.8Very high93.2Very high52 Ų5256.6 Ų56.624%0.24329%0.288CS..THydrogen-bonded Turntrans-113.619-175-59.3-176.3148.600113.2W16 I17 P19 T23 Q24 F25W16-E21 VanDerWaalsContact CA-OE2 3.24Å; W16-E21 WeakPolarHBondContact CA-OE2 3.18Å; W16-E21 HydrophobicContact CB-CB 4.21Å; I17-E21 PolarHBondContact N-OE2 3.05Å; I17-E21 WeakPolarHBondContact O-CB 3.49Å; I17-E21 PolarHBondContact O-N 2.99Å; P19-E21 VanDerWaalsContact C-N 3.28Å; P19-E21 PolarHBondContact O-N 2.83Å; E21-T23 PolarHBondContact O-N 2.97Å; E21-Q24 VanDerWaalsContact C-OE1 3.31Å; E21-Q24 VanDerWaalsContact CA-OE1 3.24Å; E21-Q24 PolarHBondContact O-N 3.05Å; E21-Q24 PolarHBondContact O-OE1 3.29Å; E21-F25 PolarHBondContact O-N 3.03Å
22Y91.4Very high93Very high66 Ų6656.8 Ų56.826%0.25929%0.289SS..Hα-helixtrans-54-50.9179176.6-94.5000112.2F18 P19 Q24 F25 Q26F18-Y22 HydrophobicContact CD1-CD2 4.01Å; F18-Y22 AromaticContact CE1-CD2 3.39Å; F18-Y22 HydrophobicContact CE1-CD2 3.39Å; F18-Y22 HydrophobicContact CE1-CE2 4.1Å; F18-Y22 HydrophobicContact CE1-CG 4.36Å; F18-Y22 AromaticContact CZ-CD2 3.87Å; F18-Y22 HydrophobicContact CZ-CD2 3.87Å; P19-Y22 WeakPolarHBondContact O-CB 3.33Å; P19-Y22 PolarHBondContact O-N 3.46Å; Y22-Q24 VanDerWaalsContact C-N 3.33Å; Y22-Q24 PolarHBondContact O-N 2.87Å; Y22-F25 WeakPolarHBondContact O-CB 3.32Å; Y22-F25 PolarHBondContact O-N 3.2Å; Y22-Q26 HydrophobicContact CD1-CG 4.12Å; Y22-Q26 HydrophobicContact CE1-CG 3.68Å; Y22-Q26 HydrophobicContact CE2-CG 4.19Å; Y22-Q26 WeakPolarHBondContact O-CG 2.84Å; Y22-Q26 PolarHBondContact O-N 3.43Å
23T91.6Very high92.6Very high88 Ų8860.5 Ų60.554%0.5430%0.298SS..Hα-helixtrans-63.7-39.5-177.5-54.60000111.8E21 Q26 N27E21-T23 PolarHBondContact O-N 2.97Å; T23-Q26 PolarHBondContact O-N 2.82Å; T23-N27 WeakPolarHBondContact O-CB 3.41Å; T23-N27 VanDerWaalsContact O-CG 3.25Å; T23-N27 PolarHBondContact O-N 3.33Å; T23-N27 PolarHBondContact O-ND2 3.02Å
24Q93.4Very high92.5Very high97 Ų9769.3 Ų69.345%0.45333%0.331SS..Hα-helixtrans-64.3-42.4177.7-64.685.8-32.300110.5E21 Y22 N27 Y28E21-Q24 VanDerWaalsContact C-OE1 3.31Å; E21-Q24 VanDerWaalsContact CA-OE1 3.24Å; E21-Q24 PolarHBondContact O-N 3.05Å; E21-Q24 PolarHBondContact O-OE1 3.29Å; Y22-Q24 VanDerWaalsContact C-N 3.33Å; Y22-Q24 PolarHBondContact O-N 2.87Å; Q24-N27 PolarHBondContact O-N 3.43Å; Q24-Y28 PolarHBondContact O-N 3.42Å
25F93.1Very high92.4Very high0 Ų067.2 Ų67.20%033%0.325CS..Hα-helixtrans-63.8-46.2174.2174.5-104.7000112W16 F18 E21 Y22 N27 Y28 V29 F41 C60 L63 V71W16-F25 HydrophobicContact CB-CB 4.21Å; W16-F25 HydrophobicContact CD2-CB 4.28Å; W16-F25 AromaticContact CD2-CD2 3.72Å; W16-F25 HydrophobicContact CD2-CD2 3.72Å; W16-F25 HydrophobicContact CD2-CG 4.47Å; W16-F25 AromaticContact CE3-CD2 3.73Å; W16-F25 HydrophobicContact CE3-CD2 3.73Å; W16-F25 HydrophobicContact CE3-CE2 4.24Å; W16-F25 HydrophobicContact CG-CB 3.85Å; W16-F25 HydrophobicContact CG-CD2 4.11Å; W16-F25 HydrophobicContact CG-CG 4.43Å; W16-F25 HydrophobicContact CZ3-CD2 4.19Å; W16-F25 HydrophobicContact CZ3-CE2 4.4Å; F18-F25 HydrophobicContact CE2-CB 3.84Å; F18-F25 HydrophobicContact CE2-CD1 4.18Å; F18-F25 HydrophobicContact CE2-CG 4.05Å; F18-F25 HydrophobicContact CZ-CB 4Å; F18-F25 AromaticContact CZ-CD1 3.57Å; F18-F25 HydrophobicContact CZ-CD1 3.57Å; F18-F25 HydrophobicContact CZ-CE1 4.23Å; F18-F25 AromaticContact CZ-CG 3.92Å; F18-F25 HydrophobicContact CZ-CG 3.92Å; E21-F25 PolarHBondContact O-N 3.03Å; Y22-F25 WeakPolarHBondContact O-CB 3.32Å; Y22-F25 PolarHBondContact O-N 3.2Å; F25-N27 VanDerWaalsContact C-N 3.31Å; F25-N27 PolarHBondContact O-N 3.02Å; F25-Y28 WeakPolarHBondContact O-CB 3.14Å; F25-Y28 PolarHBondContact O-N 3Å; F25-Y28 VanDerWaalsContact O-N 3.1Å; F25-V29 HydrophobicContact CD1-CG2 4.27Å; F25-V29 HydrophobicContact CD2-CG2 4.34Å; F25-V29 HydrophobicContact CE1-CG2 3.87Å; F25-V29 HydrophobicContact CE2-CG2 3.9Å; F25-V29 HydrophobicContact CZ-CG2 3.68Å; F25-V29 WeakPolarHBondContact O-CG2 3.38Å; F25-V29 PolarHBondContact O-N 3.36Å; F25-F41 AromaticContact CE2-CD1 3.88Å; F25-F41 HydrophobicContact CE2-CD1 3.88Å; F25-F41 HydrophobicContact CE2-CD2 4.46Å; F25-F41 AromaticContact CE2-CE1 3.78Å; F25-F41 HydrophobicContact CE2-CE1 3.78Å; F25-F41 HydrophobicContact CE2-CE2 4.38Å; F25-F41 HydrophobicContact CE2-CG 4.22Å; F25-F41 HydrophobicContact CE2-CZ 4.04Å; F25-F41 HydrophobicContact CZ-CD2 4.42Å; F25-F41 HydrophobicContact CZ-CE2 4.49Å; F25-F41 HydrophobicContact CZ-CG 4.44Å; F25-C60 HydrophobicContact CE1-CB 3.71Å; F25-C60 HydrophobicContact CZ-CB 3.77Å; F25-C60 VanDerWaalsContact CZ-SG 3.59Å; F25-L63 HydrophobicContact CE1-CD1 3.75Å; F25-L63 HydrophobicContact CZ-CD1 4.25Å; F25-V71 HydrophobicContact CD2-CG1 4.1Å; F25-V71 HydrophobicContact CE2-CB 4.38Å; F25-V71 HydrophobicContact CE2-CG1 3.51Å; F25-V71 HydrophobicContact CZ-CG1 3.77Å
26Q90.8Very high92.2Very high30 Ų3075.9 Ų75.914%0.1435%0.352CS..Hα-helixtrans-60-40.6177.7-71.1-60.9-2900112.1Y22 T23 Y28 V29 K30 C60Y22-Q26 HydrophobicContact CD1-CG 4.12Å; Y22-Q26 HydrophobicContact CE1-CG 3.68Å; Y22-Q26 HydrophobicContact CE2-CG 4.19Å; Y22-Q26 WeakPolarHBondContact O-CG 2.84Å; Y22-Q26 PolarHBondContact O-N 3.43Å; T23-Q26 PolarHBondContact O-N 2.82Å; Q26-Y28 VanDerWaalsContact C-N 3.35Å; Q26-Y28 PolarHBondContact O-N 2.87Å; Q26-V29 PolarHBondContact O-N 3.11Å; Q26-K30 WeakPolarHBondContact O-CG 3.45Å; Q26-K30 PolarHBondContact O-N 3.18Å; Q26-C60 PolarHBondContact NE2-O 3.49Å; Q26-C60 VanDerWaalsContact NE2-O 3.17Å
27N92.6Very high91.9Very high90 Ų9081 Ų8148%0.48138%0.375SS..Hα-helixtrans-63.1-41174.7-71.5-17.7000111.9T23 Q24 F25 K30 E31T23-N27 WeakPolarHBondContact O-CB 3.41Å; T23-N27 VanDerWaalsContact O-CG 3.25Å; T23-N27 PolarHBondContact O-N 3.33Å; T23-N27 PolarHBondContact O-ND2 3.02Å; Q24-N27 PolarHBondContact O-N 3.43Å; F25-N27 VanDerWaalsContact C-N 3.31Å; F25-N27 PolarHBondContact O-N 3.02Å; N27-K30 PolarHBondContact O-N 3.31Å; N27-E31 PolarHBondContact O-N 3.27Å
28Y93.2Very high91.6Very high31 Ų3181.6 Ų81.612%0.12238%0.376CS..Hα-helixtrans-63-44.1175.8178.8-115.5000112.4R14 W16 Q24 F25 Q26 K30 E31 L32 F41 E73R14-Y28 VanDerWaalsContact NH1-CE2 3.32Å; W16-Y28 AromaticContact CH2-CD1 3.42Å; W16-Y28 HydrophobicContact CH2-CD1 3.42Å; W16-Y28 VanDerWaalsContact CH2-CD1 3.42Å; W16-Y28 AromaticContact CH2-CE1 3.44Å; W16-Y28 HydrophobicContact CH2-CE1 3.44Å; W16-Y28 VanDerWaalsContact CH2-CE1 3.44Å; W16-Y28 HydrophobicContact CH2-CG 4.24Å; W16-Y28 AromaticContact CZ2-CD1 3.35Å; W16-Y28 HydrophobicContact CZ2-CD1 3.35Å; W16-Y28 HydrophobicContact CZ2-CD2 4.49Å; W16-Y28 AromaticContact CZ2-CE1 3.8Å; W16-Y28 HydrophobicContact CZ2-CE1 3.8Å; W16-Y28 AromaticContact CZ2-CG 3.73Å; W16-Y28 HydrophobicContact CZ2-CG 3.73Å; W16-Y28 HydrophobicContact CZ3-CD1 4.47Å; Q24-Y28 PolarHBondContact O-N 3.42Å; F25-Y28 WeakPolarHBondContact O-CB 3.14Å; F25-Y28 PolarHBondContact O-N 3Å; F25-Y28 VanDerWaalsContact O-N 3.1Å; Q26-Y28 VanDerWaalsContact C-N 3.35Å; Q26-Y28 PolarHBondContact O-N 2.87Å; Y28-K30 PolarHBondContact O-N 3.04Å; Y28-E31 WeakPolarHBondContact O-CB 3.35Å; Y28-E31 PolarHBondContact O-N 2.97Å; Y28-L32 HydrophobicContact CD1-CD1 3.96Å; Y28-L32 HydrophobicContact CD1-CG 4.49Å; Y28-L32 HydrophobicContact CE1-CD1 3.46Å; Y28-L32 VanDerWaalsContact CE1-CD1 3.46Å; Y28-L32 HydrophobicContact CE1-CG 4.08Å; Y28-L32 HydrophobicContact CE2-CD1 4.43Å; Y28-L32 HydrophobicContact CE2-CD2 4.33Å; Y28-L32 HydrophobicContact CE2-CG 4.16Å; Y28-L32 WeakPolarHBondContact O-CG 3.35Å; Y28-L32 PolarHBondContact O-N 3.13Å; Y28-F41 HydrophobicContact CD1-CE1 4.37Å; Y28-F41 HydrophobicContact CD1-CZ 4.33Å; Y28-F41 HydrophobicContact CE1-CE1 4.01Å; Y28-F41 HydrophobicContact CE1-CZ 4.02Å; Y28-E73 WeakPolarHBondContact CE1-OE1 3.45Å; Y28-E73 PolarHBondContact OH-OE1 2.95Å
29V91.1Very high91.6Very high9 Ų985 Ų856%0.05539%0.39CS..Hα-helixtrans-62-43.7175.9171.80000111.2F25 Q26 E31 L32 R33 C60F25-V29 HydrophobicContact CD1-CG2 4.27Å; F25-V29 HydrophobicContact CD2-CG2 4.34Å; F25-V29 HydrophobicContact CE1-CG2 3.87Å; F25-V29 HydrophobicContact CE2-CG2 3.9Å; F25-V29 HydrophobicContact CZ-CG2 3.68Å; F25-V29 WeakPolarHBondContact O-CG2 3.38Å; F25-V29 PolarHBondContact O-N 3.36Å; Q26-V29 PolarHBondContact O-N 3.11Å; V29-E31 VanDerWaalsContact C-N 3.29Å; V29-E31 PolarHBondContact O-N 3.39Å; V29-L32 WeakPolarHBondContact O-CB 3.49Å; V29-L32 PolarHBondContact O-N 2.93Å; V29-R33 WeakPolarHBondContact O-CG 3.34Å; V29-R33 PolarHBondContact O-N 2.89Å; V29-C60 HydrophobicContact CB-CB 4.35Å; V29-C60 HydrophobicContact CG1-CB 3.88Å; V29-C60 HydrophobicContact CG2-CB 3.64Å
30K90.7Very high91.6Very high134 Ų13483 Ų8358%0.58338%0.377SS*.Hα-helixtrans-59-41.3174.7-73.7174.5-177.4178.80111.6Q26 N27 Y28 R33 R34Q26-K30 WeakPolarHBondContact O-CG 3.45Å; Q26-K30 PolarHBondContact O-N 3.18Å; N27-K30 PolarHBondContact O-N 3.31Å; Y28-K30 PolarHBondContact O-N 3.04Å; K30-R33 PolarHBondContact O-N 2.8Å; K30-R34 PolarHBondContact O-N 3.1Å
31E92.3Very high91.6Very high78 Ų7879.5 Ų79.536%0.36435%0.348SS..Hα-helixtrans-65.5-42.8176.4-166.4-169.6170.900112.3N27 Y28 V29 R33 R34 K35N27-E31 PolarHBondContact O-N 3.27Å; Y28-E31 WeakPolarHBondContact O-CB 3.35Å; Y28-E31 PolarHBondContact O-N 2.97Å; V29-E31 VanDerWaalsContact C-N 3.29Å; V29-E31 PolarHBondContact O-N 3.39Å; E31-R33 VanDerWaalsContact C-N 3.31Å; E31-R33 PolarHBondContact O-N 3.27Å; E31-R34 PolarHBondContact O-N 3.48Å; E31-K35 HydrophobicContact CG-CD 4.47Å; E31-K35 WeakPolarHBondContact O-CG 3.4Å; E31-K35 PolarHBondContact O-N 3.01Å; E31-K35 WeakPolarHBondContact OE1-CE 3.5Å; E31-K35 IonicContact OE1-NZ 3.1Å; E31-K35 PolarHBondContact OE1-NZ 2.88Å
32L91.3Very high91.6Very high17 Ų1777.7 Ų77.79%0.08934%0.34CS..Hα-helixtrans-58-44.6174.7-76.4176.5000111.5Y28 V29 K35 R36 K37 K39 F41Y28-L32 HydrophobicContact CD1-CD1 3.96Å; Y28-L32 HydrophobicContact CD1-CG 4.49Å; Y28-L32 HydrophobicContact CE1-CD1 3.46Å; Y28-L32 VanDerWaalsContact CE1-CD1 3.46Å; Y28-L32 HydrophobicContact CE1-CG 4.08Å; Y28-L32 HydrophobicContact CE2-CD1 4.43Å; Y28-L32 HydrophobicContact CE2-CD2 4.33Å; Y28-L32 HydrophobicContact CE2-CG 4.16Å; Y28-L32 WeakPolarHBondContact O-CG 3.35Å; Y28-L32 PolarHBondContact O-N 3.13Å; V29-L32 WeakPolarHBondContact O-CB 3.49Å; V29-L32 PolarHBondContact O-N 2.93Å; L32-K35 CarbonylContact O-C 3.52Å; L32-K35 PolarHBondContact O-N 2.77Å; L32-R36 PolarHBondContact O-N 3.27Å; L32-R36 VanDerWaalsContact O-N 3.1Å; L32-K37 CarbonylContact C-O 3.59Å; L32-K37 HydrophobicContact CD2-CB 3.96Å; L32-K37 PolarHBondContact O-N 3.2Å; L32-K39 HydrophobicContact CD1-CB 4.01Å; L32-K39 HydrophobicContact CD1-CG 3.95Å; L32-K39 HydrophobicContact CD2-CG 4.15Å; L32-F41 HydrophobicContact CD1-CZ 3.94Å
33R88.2Confident91.6Very high123 Ų12375.5 Ų75.546%0.46433%0.333SS..Hα-helixtrans-61-46.4175.3-71.5171.9179.5-156.1-11.1112.4V29 K30 E31 K35 R36 E61V29-R33 WeakPolarHBondContact O-CG 3.34Å; V29-R33 PolarHBondContact O-N 2.89Å; K30-R33 PolarHBondContact O-N 2.8Å; E31-R33 VanDerWaalsContact C-N 3.31Å; E31-R33 PolarHBondContact O-N 3.27Å; R33-K35 PolarHBondContact O-N 3.24Å; R33-R36 WeakPolarHBondContact O-CA 3.41Å; R33-R36 PolarHBondContact O-N 3.49Å; R33-E61 IonicContact CZ-OE1 2.91Å; R33-E61 IonicContact NH1-OE1 3.04Å; R33-E61 PolarHBondContact NH1-OE1 2.95Å; R33-E61 IonicContact NH2-OE1 2.72Å; R33-E61 PolarHBondContact NH2-OE1 3.13Å
34R91.7Very high91.5Very high191 Ų19172.6 Ų72.672%0.72131%0.313SS*.Hα-helixtrans-57.4-37.1175.8-169.7-176.670.691.2-4.6111.6K30 E31 R36K30-R34 PolarHBondContact O-N 3.1Å; E31-R34 PolarHBondContact O-N 3.48Å; R34-R36 VanDerWaalsContact C-N 3.27Å; R34-R36 PolarHBondContact O-N 3.21Å
35K93.8Very high91.2Very high101 Ų10170.2 Ų70.244%0.43931%0.305SS..THydrogen-bonded Turntrans-82.93.7176-66.8-179.4-175.9173.30113.9E31 L32 R33 K37E31-K35 HydrophobicContact CG-CD 4.47Å; E31-K35 WeakPolarHBondContact O-CG 3.4Å; E31-K35 PolarHBondContact O-N 3.01Å; E31-K35 WeakPolarHBondContact OE1-CE 3.5Å; E31-K35 IonicContact OE1-NZ 3.1Å; E31-K35 PolarHBondContact OE1-NZ 2.88Å; L32-K35 CarbonylContact O-C 3.52Å; L32-K35 PolarHBondContact O-N 2.77Å; R33-K35 PolarHBondContact O-N 3.24Å; K35-K37 HydrophobicContact CB-CD 4.39Å; K35-K37 HydrophobicContact CB-CG 4.18Å; K35-K37 PolarHBondContact O-N 3.2Å
36R90.2Very high90.2Very high238 Ų23873.2 Ų73.290%0.89833%0.33SS*.THydrogen-bonded Turntrans50.835.2-173.8-59.3-178.1178.6173.5-1.1113L32 R33 R34L32-R36 PolarHBondContact O-N 3.27Å; L32-R36 VanDerWaalsContact O-N 3.1Å; R33-R36 WeakPolarHBondContact O-CA 3.41Å; R33-R36 PolarHBondContact O-N 3.49Å; R34-R36 VanDerWaalsContact C-N 3.27Å; R34-R36 PolarHBondContact O-N 3.21Å
37K89.2Confident89.1Confident131 Ų13179.8 Ų79.857%0.5737%0.366SS*.  trans-102.9130.3176.8-69.7-172.9178.9-174.80109.6L32 K35L32-K37 CarbonylContact C-O 3.59Å; L32-K37 HydrophobicContact CD2-CB 3.96Å; L32-K37 PolarHBondContact O-N 3.2Å; K35-K37 HydrophobicContact CB-CD 4.39Å; K35-K37 HydrophobicContact CB-CG 4.18Å; K35-K37 PolarHBondContact O-N 3.2Å
38Q86.8Confident87.6Confident111 Ų11177.5 Ų77.552%0.51936%0.364SS..  trans-102.1136.1171.2-161.6177.429.600109.3R58Q38-R58 VanDerWaalsContact CD-NH2 3.29Å
39K92Very high86Confident74 Ų7479.2 Ų79.232%0.32238%0.384SS..  trans-130.3151.8175.7-74.7-67.5-172.5172.80109.4L32 F41L32-K39 HydrophobicContact CD1-CB 4.01Å; L32-K39 HydrophobicContact CD1-CG 3.95Å; L32-K39 HydrophobicContact CD2-CG 4.15Å; K39-F41 HydrophobicContact CB-CE2 4.03Å; K39-F41 HydrophobicContact CB-CZ 3.93Å
40T93.5Very high84.5Confident6 Ų684.7 Ų84.74%0.03741%0.411CS..  trans-101.8140.8173-54.30000108.1L56 I57 R58 Y74 P120 L125T40-L56 HydrophobicContact CG2-CB 4.37Å; T40-L56 HydrophobicContact CG2-CD2 4.07Å; T40-I57 WeakPolarHBondContact CA-O 3.42Å; T40-R58 HydrophobicContact CG2-CG 4.05Å; T40-R58 WeakPolarHBondContact OG1-CG 3.38Å; T40-R58 PolarHBondContact OG1-NE 3.43Å; T40-Y74 HydrophobicContact CG2-CD1 4.21Å; T40-Y74 HydrophobicContact CG2-CG 4.27Å; T40-Y74 VanDerWaalsContact O-CB 3.31Å; T40-Y74 WeakPolarHBondContact O-CB 3.48Å; T40-Y74 PolarHBondContact O-N 3.29Å; T40-P120 HydrophobicContact CG2-CB 3.84Å; T40-P120 HydrophobicContact CG2-CG 3.99Å; T40-P120 WeakPolarHBondContact OG1-CG 3.22Å; T40-L125 HydrophobicContact CG2-CD2 4.04Å
41F93.9Very high83.1Confident3 Ų378.8 Ų78.81%0.01339%0.388CS..EExtended strand (participates in β ladder)trans-122.7149.1177.5-55.1-89.3000109.6W16 F25 Y28 L32 K39 L56 I57 C60 V71 Q72 E73W16-F41 HydrophobicContact CH2-CE1 4.09Å; W16-F41 HydrophobicContact CZ3-CD1 4.06Å; W16-F41 AromaticContact CZ3-CE1 3.8Å; W16-F41 HydrophobicContact CZ3-CE1 3.8Å; F25-F41 AromaticContact CE2-CD1 3.88Å; F25-F41 HydrophobicContact CE2-CD1 3.88Å; F25-F41 HydrophobicContact CE2-CD2 4.46Å; F25-F41 AromaticContact CE2-CE1 3.78Å; F25-F41 HydrophobicContact CE2-CE1 3.78Å; F25-F41 HydrophobicContact CE2-CE2 4.38Å; F25-F41 HydrophobicContact CE2-CG 4.22Å; F25-F41 HydrophobicContact CE2-CZ 4.04Å; F25-F41 HydrophobicContact CZ-CD2 4.42Å; F25-F41 HydrophobicContact CZ-CE2 4.49Å; F25-F41 HydrophobicContact CZ-CG 4.44Å; Y28-F41 HydrophobicContact CD1-CE1 4.37Å; Y28-F41 HydrophobicContact CD1-CZ 4.33Å; Y28-F41 HydrophobicContact CE1-CE1 4.01Å; Y28-F41 HydrophobicContact CE1-CZ 4.02Å; L32-F41 HydrophobicContact CD1-CZ 3.94Å; K39-F41 HydrophobicContact CB-CE2 4.03Å; K39-F41 HydrophobicContact CB-CZ 3.93Å; F41-L56 CarbonylContact O-C 3.55Å; F41-L56 WeakPolarHBondContact O-CA 3.3Å; F41-I57 HydrophobicContact CB-CD1 4.35Å; F41-I57 HydrophobicContact CB-CG1 3.85Å; F41-I57 PolarHBondContact N-O 2.71Å; F41-I57 PolarHBondContact O-N 2.95Å; F41-C60 VanDerWaalsContact CD2-SG 3.57Å; F41-C60 VanDerWaalsContact CE2-SG 3.52Å; F41-V71 HydrophobicContact CB-CG1 3.79Å; F41-V71 HydrophobicContact CD1-CG1 4.05Å; F41-V71 HydrophobicContact CG-CG1 4.12Å; F41-Q72 CarbonylContact C-O 3.55Å; F41-Q72 VanDerWaalsContact CA-O 3.25Å; F41-Q72 WeakPolarHBondContact CA-O 3.46Å; F41-E73 HydrophobicContact CD1-CG 4.1Å; F41-E73 HydrophobicContact CE1-CG 3.82Å
42I92.6Very high81.9Confident14 Ų1481.5 Ų81.57%0.07240%0.4CS..EExtended strand (participates in β ladder)trans-109.4128.3173.5-171.2170.4000108.5K44 I54 S55 Q72 Y74 L132I42-K44 HydrophobicContact CG1-CG 4.4Å; I42-I54 HydrophobicContact CD1-CG2 3.64Å; I42-I54 HydrophobicContact CG1-CG2 3.55Å; I42-S55 WeakPolarHBondContact CA-O 3.48Å; I42-Q72 HydrophobicContact CG2-CB 3.83Å; I42-Q72 HydrophobicContact CG2-CG 4.36Å; I42-Q72 PolarHBondContact N-O 3.03Å; I42-Q72 PolarHBondContact O-N 3.34Å; I42-Y74 HydrophobicContact CB-CD2 4.14Å; I42-Y74 HydrophobicContact CD1-CD2 4.33Å; I42-L132 HydrophobicContact CD1-CD2 4.15Å
43L91.7Very high81.2Confident20 Ų2083.7 Ų83.711%0.10543%0.427CS..EExtended strand (participates in β ladder)trans-94.5130.5174.2-83.871.7000108.6I54 S55 I57 L63 F69 I70 V71L43-I54 VanDerWaalsContact O-CA 3.31Å; L43-I54 WeakPolarHBondContact O-CA 3.34Å; L43-I54 WeakPolarHBondContact O-CG2 3.36Å; L43-S55 PolarHBondContact N-O 3.04Å; L43-S55 PolarHBondContact O-N 3.29Å; L43-I57 HydrophobicContact CD1-CB 4.29Å; L43-I57 HydrophobicContact CD1-CD1 3.57Å; L43-I57 HydrophobicContact CD1-CG1 3.51Å; L43-I57 HydrophobicContact CD1-CG2 3.88Å; L43-L63 HydrophobicContact CD2-CD2 3.62Å; L43-F69 HydrophobicContact CD2-CD2 4.01Å; L43-F69 HydrophobicContact CD2-CE2 3.76Å; L43-F69 HydrophobicContact CD2-CZ 4.4Å; L43-F69 HydrophobicContact CG-CD2 4.04Å; L43-F69 HydrophobicContact CG-CE2 4.06Å; L43-I70 WeakPolarHBondContact CA-O 3.43Å; L43-V71 HydrophobicContact CG-CG2 4.4Å
44K90.5Very high81Confident27 Ų2779 Ų7912%0.11741%0.411CS..EExtended strand (participates in β ladder)trans-127.6124.9175.8-54.6169.7170.4177.50108.8I42 I54 F69 I70I42-K44 HydrophobicContact CG1-CG 4.4Å; K44-I54 HydrophobicContact CG-CD1 4.26Å; K44-I54 HydrophobicContact CG-CG1 4.33Å; K44-F69 CarbonylContact O-C 3.6Å; K44-F69 WeakPolarHBondContact O-CA 3.31Å; K44-F69 WeakPolarHBondContact O-CB 3.41Å; K44-I70 HydrophobicContact CB-CD1 4.09Å; K44-I70 HydrophobicContact CB-CG1 3.66Å; K44-I70 HydrophobicContact CD-CD1 3.89Å; K44-I70 HydrophobicContact CD-CG1 4.28Å; K44-I70 HydrophobicContact CG-CG1 4.37Å; K44-I70 PolarHBondContact N-O 3.5Å; K44-I70 PolarHBondContact O-N 3.11Å
45P85.8Confident80.8Confident47 Ų4772.2 Ų72.231%0.30539%0.393SS..EExtended strand (participates in β ladder)trans-66145.9178.221.7-25.7000110.9N47 G48 H52P45-N47 VanDerWaalsContact C-N 3.26Å; P45-N47 PolarHBondContact O-N 3.26Å; P45-G48 PolarHBondContact O-N 3.49Å; P45-G48 VanDerWaalsContact O-N 3.08Å; P45-H52 VanDerWaalsContact CG-O 3.29Å; P45-H52 WeakPolarHBondContact CG-O 3.45Å
46A73.3Confident80.6Confident62 Ų6267.9 Ų67.951%0.51238%0.375SS..THydrogen-bonded Turntrans-61-31-171.300000114.2H68A46-H68 HydrophobicContact CB-CB 4.14Å; A46-H68 WeakPolarHBondContact CB-O 3.39Å; A46-H68 PolarHBondContact N-O 2.97Å
47N66.5Low80.6Confident168 Ų16857.8 Ų57.890%0.89834%0.338SS*.THydrogen-bonded Turntrans-113.920.5177.6-64-24.1000112.3P45P45-N47 VanDerWaalsContact C-N 3.26Å; P45-N47 PolarHBondContact O-N 3.26Å
48G61.4Low80.4Confident43 Ų4354 Ų5444%0.44332%0.32SS..  trans-70.7140.4177.600000111.9P45P45-G48 PolarHBondContact O-N 3.49Å; P45-G48 VanDerWaalsContact O-N 3.08Å
49A60.2Low79.9Confident66 Ų6652.3 Ų52.355%0.54532%0.321SS..  trans-128.5166.5163.500000108.9G51 H52A49-G51 PolarHBondContact O-N 3.34Å; A49-H52 PolarHBondContact O-N 2.67Å
50M59.7Low78.9Confident124 Ų12449 Ų4961%0.61131%0.306SS*.THydrogen-bonded Turntrans61.317.7169.8-59.9-172.9-172.500115.2H52 S136M50-H52 VanDerWaalsContact C-N 3.31Å; M50-H52 PolarHBondContact O-N 2.81Å; M50-S136 VanDerWaalsContact C-OG 3.26Å; M50-S136 WeakPolarHBondContact CA-OG 3.42Å; M50-S136 WeakPolarHBondContact CB-OG 3.31Å; M50-S136 PolarHBondContact O-OG 3.27Å
51G60.4Low77.5Confident10 Ų1054.1 Ų54.110%0.10333%0.33CS..THydrogen-bonded Turntrans80.34-179.900000115.3A49 I54A49-G51 PolarHBondContact O-N 3.34Å; G51-I54 PolarHBondContact O-N 3.47Å
52H67.2Low76.1Confident135 Ų13563.2 Ų63.263%0.62537%0.37SS*.THydrogen-bonded Turntrans-68.2134.1178.8-75.8-67.1000112P45 A49 M50 I54P45-H52 VanDerWaalsContact CG-O 3.29Å; P45-H52 WeakPolarHBondContact CG-O 3.45Å; A49-H52 PolarHBondContact O-N 2.67Å; M50-H52 VanDerWaalsContact C-N 3.31Å; M50-H52 PolarHBondContact O-N 2.81Å; H52-I54 PolarHBondContact O-N 3.23Å
53G75.9Confident75.4Confident63 Ų6363.6 Ų63.665%0.64937%0.371SS*.THydrogen-bonded Turntrans74.57.2178.800000114.7
54I85Confident74.7Confident25 Ų2565.1 Ų65.113%0.12838%0.383CS..  trans-75.9131.2174.7-62-174.6000109.8I42 L43 K44 G51 H52 L132I42-I54 HydrophobicContact CD1-CG2 3.64Å; I42-I54 HydrophobicContact CG1-CG2 3.55Å; L43-I54 VanDerWaalsContact O-CA 3.31Å; L43-I54 WeakPolarHBondContact O-CA 3.34Å; L43-I54 WeakPolarHBondContact O-CG2 3.36Å; K44-I54 HydrophobicContact CG-CD1 4.26Å; K44-I54 HydrophobicContact CG-CG1 4.33Å; G51-I54 PolarHBondContact O-N 3.47Å; H52-I54 PolarHBondContact O-N 3.23Å; I54-L132 HydrophobicContact CB-CD1 4.12Å; I54-L132 HydrophobicContact CB-CD2 4.49Å; I54-L132 HydrophobicContact CG2-CD1 4.15Å; I54-L132 HydrophobicContact CG2-CD2 3.71Å
55S87.3Confident74.1Confident48 Ų4865.8 Ų65.834%0.33639%0.391SS..EExtended strand (participates in β ladder)trans-136.2155.417560.10000111.2I42 L43I42-S55 WeakPolarHBondContact CA-O 3.48Å; L43-S55 PolarHBondContact N-O 3.04Å; L43-S55 PolarHBondContact O-N 3.29Å
56L89.7Confident73.7Confident11 Ų1171 Ų716%0.05841%0.411CS..EExtended strand (participates in β ladder)trans-105.7139.9173.1-76.376.8000109.8T40 F41 Y74 P120 L125 L128 H131T40-L56 HydrophobicContact CG2-CB 4.37Å; T40-L56 HydrophobicContact CG2-CD2 4.07Å; F41-L56 CarbonylContact O-C 3.55Å; F41-L56 WeakPolarHBondContact O-CA 3.3Å; L56-Y74 HydrophobicContact CD2-CD1 4.34Å; L56-Y74 HydrophobicContact CD2-CD2 3.98Å; L56-Y74 HydrophobicContact CD2-CE1 4.21Å; L56-Y74 HydrophobicContact CD2-CE2 3.86Å; L56-Y74 HydrophobicContact CD2-CG 4.21Å; L56-Y74 HydrophobicContact CG-CD2 4.42Å; L56-P120 HydrophobicContact CD2-CB 4.5Å; L56-L125 HydrophobicContact CB-CB 4.44Å; L56-L125 HydrophobicContact CB-CD2 3.77Å; L56-L125 HydrophobicContact CD2-CD2 4.41Å; L56-L128 HydrophobicContact CD1-CD2 4.1Å; L56-H131 HydrophobicContact CD1-CB 4.07Å; L56-H131 HydrophobicContact CD2-CB 4.13Å
57I89.5Confident74.1Confident25 Ų2573.7 Ų73.713%0.12841%0.413CS..EExtended strand (participates in β ladder)trans-131.2150.7176.166163000111.2T40 F41 L43 L63T40-I57 WeakPolarHBondContact CA-O 3.42Å; F41-I57 HydrophobicContact CB-CD1 4.35Å; F41-I57 HydrophobicContact CB-CG1 3.85Å; F41-I57 PolarHBondContact N-O 2.71Å; F41-I57 PolarHBondContact O-N 2.95Å; L43-I57 HydrophobicContact CD1-CB 4.29Å; L43-I57 HydrophobicContact CD1-CD1 3.57Å; L43-I57 HydrophobicContact CD1-CG1 3.51Å; L43-I57 HydrophobicContact CD1-CG2 3.88Å; I57-L63 HydrophobicContact CD1-CD1 3.75Å; I57-L63 HydrophobicContact CD1-CD2 3.98Å; I57-L63 HydrophobicContact CD1-CG 4.08Å
58R86.3Confident75.2Confident53 Ų5372.1 Ų72.120%0.240%0.4CS..SBendtrans-121.9-22.9167.1-60-177.187.4-154.57.2112.4Q38 T40 D122 L125Q38-R58 VanDerWaalsContact CD-NH2 3.29Å; T40-R58 HydrophobicContact CG2-CG 4.05Å; T40-R58 WeakPolarHBondContact OG1-CG 3.38Å; T40-R58 PolarHBondContact OG1-NE 3.43Å; R58-D122 WeakPolarHBondContact CD-OD1 3.47Å; R58-D122 IonicContact NH1-OD1 3.07Å; R58-L125 HydrophobicContact CB-CD1 4.39Å; R58-L125 HydrophobicContact CG-CD1 3.9Å; R58-L125 HydrophobicContact CG-CD2 3.89Å; R58-L125 HydrophobicContact CG-CG 4.47Å
59S75.8Confident76.5Confident75 Ų7570.8 Ų70.852%0.52438%0.382SS..  trans-99.6120.8171.2-174.10000110.2
60C70.3Confident78.1Confident3 Ų369.9 Ų69.92%0.0237%0.367CS..  trans-105.113.3-171.5-53.90000113.6F25 Q26 V29 F41F25-C60 HydrophobicContact CE1-CB 3.71Å; F25-C60 HydrophobicContact CZ-CB 3.77Å; F25-C60 VanDerWaalsContact CZ-SG 3.59Å; Q26-C60 PolarHBondContact NE2-O 3.49Å; Q26-C60 VanDerWaalsContact NE2-O 3.17Å; V29-C60 HydrophobicContact CB-CB 4.35Å; V29-C60 HydrophobicContact CG1-CB 3.88Å; V29-C60 HydrophobicContact CG2-CB 3.64Å; F41-C60 VanDerWaalsContact CD2-SG 3.57Å; F41-C60 VanDerWaalsContact CE2-SG 3.52Å
61E63.9Low79.7Confident115 Ų11564 Ų6454%0.53734%0.338SS..THydrogen-bonded Turntrans-81.5-18.7-172.8-61.6-177.9162.400114R33R33-E61 IonicContact CZ-OE1 2.91Å; R33-E61 IonicContact NH1-OE1 3.04Å; R33-E61 PolarHBondContact NH1-OE1 2.95Å; R33-E61 IonicContact NH2-OE1 2.72Å; R33-E61 PolarHBondContact NH2-OE1 3.13Å
62K64.4Low81.3Confident194 Ų19464.1 Ų64.184%0.84334%0.336SS*.THydrogen-bonded Turntrans-120.826.3-169.1-61.7-173.3179.4-178.20113.9
63L78.8Confident82.7Confident21 Ų2159.3 Ų59.311%0.1131%0.314CS..  trans-78.4133.1178.5-71.3-173.7000111.4F18 F25 L43 I57 S65 F69 V71F18-L63 HydrophobicContact CE1-CB 4.24Å; F18-L63 HydrophobicContact CE1-CD1 4.12Å; F18-L63 HydrophobicContact CZ-CD1 4.26Å; F25-L63 HydrophobicContact CE1-CD1 3.75Å; F25-L63 HydrophobicContact CZ-CD1 4.25Å; L43-L63 HydrophobicContact CD2-CD2 3.62Å; I57-L63 HydrophobicContact CD1-CD1 3.75Å; I57-L63 HydrophobicContact CD1-CD2 3.98Å; I57-L63 HydrophobicContact CD1-CG 4.08Å; L63-S65 PolarHBondContact O-N 3.4Å; L63-F69 HydrophobicContact CB-CZ 4.38Å; L63-F69 HydrophobicContact CD1-CE2 4.3Å; L63-V71 HydrophobicContact CD1-CG2 3.95Å
64P77.5Confident83.6Confident52 Ų5257 Ų5734%0.33829%0.286SS..  trans-62.5125.3176.722-28.2000110.2H66 E67 F69P64-H66 VanDerWaalsContact C-N 3.3Å; P64-H66 PolarHBondContact O-N 3.17Å; P64-E67 HydrophobicContact CB-CB 4.32Å; P64-E67 HydrophobicContact CB-CG 4Å; P64-E67 HydrophobicContact CG-CB 4.2Å; P64-E67 VanDerWaalsContact CG-CD 3.5Å; P64-E67 HydrophobicContact CG-CG 4.11Å; P64-E67 WeakPolarHBondContact CG-OE2 3.45Å; P64-F69 HydrophobicContact CG-CE1 4.02Å; P64-F69 HydrophobicContact CG-CZ 4.41Å
65S76.4Confident84Confident42 Ų4257.2 Ų57.229%0.29429%0.287SS..SBendtrans-79-9.6-174.151.20000114.4P19 L63P19-S65 WeakPolarHBondContact CB-O 3.2Å; L63-S65 PolarHBondContact O-N 3.4Å
66H78.3Confident84.3Confident156 Ų15657.4 Ų57.472%0.72228%0.284SS*.SBendtrans-118.1-5.1-172.7-59.1-64.5000114P64P64-H66 VanDerWaalsContact C-N 3.3Å; P64-H66 PolarHBondContact O-N 3.17Å
67E82.2Confident84.6Confident118 Ų11861.4 Ų61.455%0.55130%0.301SS*.SBendtrans-84.3151.4179-72.4178.7-157.400111.9P64 F69P64-E67 HydrophobicContact CB-CB 4.32Å; P64-E67 HydrophobicContact CB-CG 4Å; P64-E67 HydrophobicContact CG-CB 4.2Å; P64-E67 VanDerWaalsContact CG-CD 3.5Å; P64-E67 HydrophobicContact CG-CG 4.11Å; P64-E67 WeakPolarHBondContact CG-OE2 3.45Å; E67-F69 HydrophobicContact CB-CD1 3.74Å; E67-F69 HydrophobicContact CB-CE1 3.75Å; E67-F69 WeakPolarHBondContact O-CD1 3.34Å; E67-F69 PolarHBondContact O-N 2.97Å
68H88.3Confident84.9Confident136 Ų13660.5 Ų60.563%0.6330%0.297SS*.  trans-94.497.5-178.9-70-71.1000111.3P19 A46P19-H68 WeakPolarHBondContact CD-ND1 3.45Å; A46-H68 HydrophobicContact CB-CB 4.14Å; A46-H68 WeakPolarHBondContact CB-O 3.39Å; A46-H68 PolarHBondContact N-O 2.97Å
69F90.3Very high85.4Confident14 Ų1459.7 Ų59.76%0.06130%0.295CS..EExtended strand (participates in β ladder)trans-146.4171.5174.158.1-85.9000110F18 L43 K44 L63 P64 E67 V71F18-F69 WeakPolarHBondContact CA-O 3.18Å; F18-F69 HydrophobicContact CB-CD1 4.33Å; F18-F69 HydrophobicContact CB-CD2 4.35Å; F18-F69 HydrophobicContact CB-CE1 4.21Å; F18-F69 HydrophobicContact CB-CE2 4.27Å; F18-F69 HydrophobicContact CB-CG 4.39Å; F18-F69 HydrophobicContact CB-CZ 4.2Å; F18-F69 VanDerWaalsContact CB-O 3.32Å; F18-F69 WeakPolarHBondContact CB-O 3.49Å; F18-F69 HydrophobicContact CD1-CD2 4.46Å; F18-F69 AromaticContact CD1-CE1 3.88Å; F18-F69 HydrophobicContact CD1-CE1 3.88Å; F18-F69 AromaticContact CD1-CE2 3.59Å; F18-F69 HydrophobicContact CD1-CE2 3.59Å; F18-F69 AromaticContact CD1-CZ 3.24Å; F18-F69 HydrophobicContact CD1-CZ 3.24Å; F18-F69 AromaticContact CE1-CE2 3.96Å; F18-F69 HydrophobicContact CE1-CE2 3.96Å; F18-F69 AromaticContact CE1-CZ 3.73Å; F18-F69 HydrophobicContact CE1-CZ 3.73Å; F18-F69 HydrophobicContact CG-CD2 4.4Å; F18-F69 HydrophobicContact CG-CE1 4.42Å; F18-F69 AromaticContact CG-CE2 3.92Å; F18-F69 HydrophobicContact CG-CE2 3.92Å; F18-F69 AromaticContact CG-CZ 3.93Å; F18-F69 HydrophobicContact CG-CZ 3.93Å; F18-F69 PolarHBondContact N-O 2.93Å; L43-F69 HydrophobicContact CD2-CD2 4.01Å; L43-F69 HydrophobicContact CD2-CE2 3.76Å; L43-F69 HydrophobicContact CD2-CZ 4.4Å; L43-F69 HydrophobicContact CG-CD2 4.04Å; L43-F69 HydrophobicContact CG-CE2 4.06Å; K44-F69 CarbonylContact O-C 3.6Å; K44-F69 WeakPolarHBondContact O-CA 3.31Å; K44-F69 WeakPolarHBondContact O-CB 3.41Å; L63-F69 HydrophobicContact CB-CZ 4.38Å; L63-F69 HydrophobicContact CD1-CE2 4.3Å; P64-F69 HydrophobicContact CG-CE1 4.02Å; P64-F69 HydrophobicContact CG-CZ 4.41Å; E67-F69 HydrophobicContact CB-CD1 3.74Å; E67-F69 HydrophobicContact CB-CE1 3.75Å; E67-F69 WeakPolarHBondContact O-CD1 3.34Å; E67-F69 PolarHBondContact O-N 2.97Å; F69-V71 HydrophobicContact CD2-CG2 3.86Å; F69-V71 HydrophobicContact CE2-CG2 3.44Å; F69-V71 VanDerWaalsContact CE2-CG2 3.44Å
70I92.4Very high86.3Confident47 Ų4759.2 Ų59.224%0.24129%0.286CS..EExtended strand (participates in β ladder)trans-109.313916862.6171000109.2T15 W16 I17 L43 K44T15-I70 HydrophobicContact CG2-CB 4.06Å; T15-I70 HydrophobicContact CG2-CD1 4.17Å; W16-I70 WeakPolarHBondContact O-CA 3.13Å; I17-I70 HydrophobicContact CG1-CG2 4.46Å; L43-I70 WeakPolarHBondContact CA-O 3.43Å; K44-I70 HydrophobicContact CB-CD1 4.09Å; K44-I70 HydrophobicContact CB-CG1 3.66Å; K44-I70 HydrophobicContact CD-CD1 3.89Å; K44-I70 HydrophobicContact CD-CG1 4.28Å; K44-I70 HydrophobicContact CG-CG1 4.37Å; K44-I70 PolarHBondContact N-O 3.5Å; K44-I70 PolarHBondContact O-N 3.11Å
71V93.6Very high87.3Confident0 Ų059 Ų590%029%0.285CS..EExtended strand (participates in β ladder)trans-102126.3167.2-176.20000107.1T15 W16 F18 F25 F41 L43 L63 F69T15-V71 CarbonylContact C-O 3.52Å; T15-V71 WeakPolarHBondContact CA-O 3.43Å; W16-V71 HydrophobicContact CE3-CG1 4.44Å; W16-V71 PolarHBondContact N-O 3.08Å; W16-V71 PolarHBondContact O-N 2.82Å; F18-V71 HydrophobicContact CD2-CG2 3.98Å; F18-V71 HydrophobicContact CE1-CG2 4.25Å; F18-V71 HydrophobicContact CE2-CB 4.24Å; F18-V71 HydrophobicContact CE2-CG2 3.65Å; F18-V71 HydrophobicContact CG-CG2 4.47Å; F18-V71 HydrophobicContact CZ-CG2 3.79Å; F25-V71 HydrophobicContact CD2-CG1 4.1Å; F25-V71 HydrophobicContact CE2-CB 4.38Å; F25-V71 HydrophobicContact CE2-CG1 3.51Å; F25-V71 HydrophobicContact CZ-CG1 3.77Å; F41-V71 HydrophobicContact CB-CG1 3.79Å; F41-V71 HydrophobicContact CD1-CG1 4.05Å; F41-V71 HydrophobicContact CG-CG1 4.12Å; L43-V71 HydrophobicContact CG-CG2 4.4Å; L63-V71 HydrophobicContact CD1-CG2 3.95Å; F69-V71 HydrophobicContact CD2-CG2 3.86Å; F69-V71 HydrophobicContact CE2-CG2 3.44Å; F69-V71 VanDerWaalsContact CE2-CG2 3.44Å
72Q95.1Very high88.5Confident13 Ų1358.5 Ų58.56%0.06128%0.283CS..EExtended strand (participates in β ladder)trans-128.1142.5-179-177.9172.776.500110P13 R14 T15 F41 I42 Y74P13-Q72 HydrophobicContact CB-CG 3.68Å; P13-Q72 HydrophobicContact CG-CG 4.39Å; R14-Q72 CarbonylContact O-C 3.54Å; R14-Q72 WeakPolarHBondContact O-CA 3.32Å; T15-Q72 HydrophobicContact CG2-CB 4.3Å; T15-Q72 WeakPolarHBondContact OG1-CG 3.35Å; T15-Q72 PolarHBondContact OG1-NE2 3.26Å; F41-Q72 CarbonylContact C-O 3.55Å; F41-Q72 VanDerWaalsContact CA-O 3.25Å; F41-Q72 WeakPolarHBondContact CA-O 3.46Å; I42-Q72 HydrophobicContact CG2-CB 3.83Å; I42-Q72 HydrophobicContact CG2-CG 4.36Å; I42-Q72 PolarHBondContact N-O 3.03Å; I42-Q72 PolarHBondContact O-N 3.34Å; Q72-Y74 PolarHBondContact O-N 3.41Å
73E95.1Very high89.7Confident34 Ų3450.6 Ų50.616%0.15926%0.256CS..EExtended strand (participates in β ladder)trans-60.5127.9171-76.9-171.7-178.600110.2R14 W16 Y28 F41R14-E73 HydrophobicContact CB-CB 4.46Å; R14-E73 HydrophobicContact CB-CG 3.94Å; R14-E73 WeakPolarHBondContact CD-OE1 3.45Å; R14-E73 PolarHBondContact O-N 2.78Å; W16-E73 HydrophobicContact CH2-CG 3.93Å; W16-E73 HydrophobicContact CZ3-CG 3.87Å; Y28-E73 WeakPolarHBondContact CE1-OE1 3.45Å; Y28-E73 PolarHBondContact OH-OE1 2.95Å; F41-E73 HydrophobicContact CD1-CG 4.1Å; F41-E73 HydrophobicContact CE1-CG 3.82Å
74Y95Very high90.3Very high16 Ų1652.8 Ų52.86%0.06326%0.263CS..  trans-80.6133178.2-176.4-100.6000110.6T40 I42 L56 Q72 D76 K85 Y117 P120 H131T40-Y74 HydrophobicContact CG2-CD1 4.21Å; T40-Y74 HydrophobicContact CG2-CG 4.27Å; T40-Y74 VanDerWaalsContact O-CB 3.31Å; T40-Y74 WeakPolarHBondContact O-CB 3.48Å; T40-Y74 PolarHBondContact O-N 3.29Å; I42-Y74 HydrophobicContact CB-CD2 4.14Å; I42-Y74 HydrophobicContact CD1-CD2 4.33Å; L56-Y74 HydrophobicContact CD2-CD1 4.34Å; L56-Y74 HydrophobicContact CD2-CD2 3.98Å; L56-Y74 HydrophobicContact CD2-CE1 4.21Å; L56-Y74 HydrophobicContact CD2-CE2 3.86Å; L56-Y74 HydrophobicContact CD2-CG 4.21Å; L56-Y74 HydrophobicContact CG-CD2 4.42Å; Q72-Y74 PolarHBondContact O-N 3.41Å; Y74-D76 HydrophobicContact CD1-CB 4.31Å; Y74-D76 PolarHBondContact O-N 3.38Å; Y74-D76 VanDerWaalsContact O-N 3.12Å; Y74-K85 PolarHBondContact OH-NZ 3.06Å; Y74-Y117 WeakPolarHBondContact OH-CE2 3.31Å; Y74-P120 HydrophobicContact CD1-CG 3.91Å; Y74-P120 HydrophobicContact CE1-CG 3.9Å; Y74-H131 PolarHBondContact OH-ND1 3.19Å
75L94.8Very high91.1Very high29 Ų2950.9 Ų50.915%0.15225%0.25CC..  trans-78.793.7174.9-64.6171.4000109.2P13 K77 L222 W230 L232P13-L75 HydrophobicContact CG-CD1 4.1Å; P13-L75 HydrophobicContact CG-CG 4.29Å; L75-K77 VanDerWaalsContact C-N 3.35Å; L75-K77 PolarHBondContact O-N 3.1Å; L75-L222 HydrophobicContact CB-CD2 3.72Å; L75-L222 HydrophobicContact CD1-CB 4.23Å; L75-L222 HydrophobicContact CD1-CD2 3.57Å; L75-L222 HydrophobicContact CD1-CG 4.43Å; L75-L222 HydrophobicContact CG-CD2 4.27Å; L75-W230 HydrophobicContact CD1-CB 3.5Å; L75-W230 HydrophobicContact CD1-CD2 4.03Å; L75-W230 HydrophobicContact CD1-CG 3.54Å; L75-W230 HydrophobicContact CD2-CD2 3.82Å; L75-W230 HydrophobicContact CD2-CE3 4.17Å; L75-W230 HydrophobicContact CD2-CG 4.14Å; L75-W230 HydrophobicContact CD2-CZ2 4.28Å; L75-L232 HydrophobicContact CD1-CD2 4.42Å
76D92.9Very high92Very high52 Ų5249 Ų4928%0.27824%0.236SC..SBendtrans-77.1-15.9-171.962.9-8.1000114.7Y74 P78 Y117 P120Y74-D76 HydrophobicContact CD1-CB 4.31Å; Y74-D76 PolarHBondContact O-N 3.38Å; Y74-D76 VanDerWaalsContact O-N 3.12Å; D76-P78 VanDerWaalsContact C-CD 3.41Å; D76-P78 WeakPolarHBondContact O-CD 3.42Å; D76-Y117 VanDerWaalsContact C-OH 3.25Å; D76-Y117 WeakPolarHBondContact CA-OH 3.29Å; D76-Y117 WeakPolarHBondContact O-CE1 3.41Å; D76-Y117 PolarHBondContact O-OH 3.48Å; D76-P120 HydrophobicContact CB-CG 4.06Å
77K95.3Very high92.8Very high95 Ų9541.7 Ų41.741%0.41320%0.202SC..SBendtrans-124.965.8-179.8-63.3177.9-171.8-176.20111.3L75 R225L75-K77 VanDerWaalsContact C-N 3.35Å; L75-K77 PolarHBondContact O-N 3.1Å; K77-R225 HydrophobicContact CB-CG 4.11Å; K77-R225 PolarHBondContact O-N 3.07Å
78P96.5Very high93.5Very high6 Ų636 Ų364%0.03918%0.176CC..BIsolated β-bridgetrans-66.2159.2174.731.4-35.4000111D76 L80 K85 Y117 L222 L223D76-P78 VanDerWaalsContact C-CD 3.41Å; D76-P78 WeakPolarHBondContact O-CD 3.42Å; P78-L80 HydrophobicContact CG-CD2 3.84Å; P78-K85 HydrophobicContact CB-CG 4.27Å; P78-K85 HydrophobicContact CG-CD 4.37Å; P78-K85 HydrophobicContact CG-CG 4.11Å; P78-Y117 HydrophobicContact CG-CD1 4.05Å; P78-Y117 HydrophobicContact CG-CD2 4.4Å; P78-Y117 HydrophobicContact CG-CE1 3.76Å; P78-Y117 HydrophobicContact CG-CE2 4.15Å; P78-Y117 HydrophobicContact CG-CG 4.35Å; P78-L222 HydrophobicContact CB-CD2 4.33Å; P78-L223 CarbonylContact C-O 3.58Å; P78-L223 WeakPolarHBondContact CA-O 3.47Å
79F96.3Very high93.9Very high36 Ų3630.6 Ų30.616%0.15815%0.15CC..  trans-66.8134.8161.5-168.4-105.4000108.2F86 F161 F164 L165 L223 D224 L227F79-F86 AromaticContact CD1-CE1 3.68Å; F79-F86 HydrophobicContact CD1-CE1 3.68Å; F79-F86 AromaticContact CD1-CZ 3.66Å; F79-F86 HydrophobicContact CD1-CZ 3.66Å; F79-F86 HydrophobicContact CE1-CE1 4.42Å; F79-F86 HydrophobicContact CE1-CZ 4.4Å; F79-F161 HydrophobicContact CE1-CE2 4.23Å; F79-F164 HydrophobicContact CE1-CE1 4.01Å; F79-F164 HydrophobicContact CZ-CE1 4.3Å; F79-L165 HydrophobicContact CE1-CD2 4.11Å; F79-L165 HydrophobicContact CZ-CD2 4.11Å; F79-L223 HydrophobicContact CB-CB 3.93Å; F79-L223 PolarHBondContact N-O 3.1Å; F79-D224 WeakPolarHBondContact CB-O 3.39Å; F79-D224 VanDerWaalsContact N-C 3.33Å; F79-L227 HydrophobicContact CB-CD2 4.35Å; F79-L227 HydrophobicContact CD1-CD2 3.85Å; F79-L227 HydrophobicContact CD2-CD2 3.57Å; F79-L227 HydrophobicContact CD2-CG 4.05Å; F79-L227 HydrophobicContact CE1-CD2 3.94Å; F79-L227 HydrophobicContact CE2-CD2 3.68Å; F79-L227 HydrophobicContact CE2-CG 4.07Å; F79-L227 HydrophobicContact CG-CD2 3.66Å; F79-L227 HydrophobicContact CZ-CD2 3.87Å
80L94.6Very high94.3Very high64 Ų6430 Ų3034%0.33515%0.147SC..EExtended strand (participates in β ladder)trans-112.5136.7-176-60.8-179.8000109.6P78 Y84 K85 Y117P78-L80 HydrophobicContact CG-CD2 3.84Å; L80-Y84 WeakPolarHBondContact CA-O 3.46Å; L80-K85 HydrophobicContact CD2-CB 4.35Å; L80-Y117 HydrophobicContact CD1-CD1 4.08Å; L80-Y117 HydrophobicContact CD2-CD1 3.77Å; L80-Y117 HydrophobicContact CD2-CG 3.77Å; L80-Y117 HydrophobicContact CG-CD1 4.48Å
81M90.9Very high94.6Very high0 Ų027.7 Ų27.70%014%0.135CC..EExtended strand (participates in β ladder)trans-107.9113.1173.1-171.816274.200107.6G83 Y84 F86 V110 M112 W160 F161 F164M81-G83 PolarHBondContact O-N 3.02Å; M81-Y84 PolarHBondContact N-O 2.79Å; M81-Y84 PolarHBondContact O-N 2.91Å; M81-F86 HydrophobicContact CB-CD1 3.68Å; M81-F86 HydrophobicContact CB-CE1 3.73Å; M81-V110 HydrophobicContact CE-CG1 3.96Å; M81-M112 HydrophobicContact CE-CE 4.17Å; M81-M112 HydrophobicContact CE-CG 3.6Å; M81-M112 HydrophobicContact CE-SD 3.14Å; M81-M112 WeakPolarHBondContact CE-SD 3.36Å; M81-W160 HydrophobicContact CE-CZ3 4.09Å; M81-W160 HydrophobicContact SD-CE3 4.49Å; M81-W160 HydrophobicContact SD-CH2 3.88Å; M81-W160 HydrophobicContact SD-CZ3 3.38Å; M81-W160 WeakPolarHBondContact SD-CZ3 3.46Å; M81-F161 HydrophobicContact SD-CD2 4.09Å; M81-F164 HydrophobicContact CG-CE1 4.32Å; M81-F164 HydrophobicContact CG-CE2 4.29Å; M81-F164 HydrophobicContact CG-CZ 4.1Å
82E89.1Confident94.8Very high104 Ų10427.7 Ų27.749%0.48614%0.135SC..THydrogen-bonded Turntrans55.826.4-177.5-62.3155.8-148.100113.6Y84 R156E82-Y84 HydrophobicContact CB-CD2 4.39Å; E82-R156 IonicContact OE1-CZ 3.83Å; E82-R156 IonicContact OE1-NH1 2.68Å; E82-R156 PolarHBondContact OE1-NH1 3.36Å; E82-R156 IonicContact OE1-NH2 3.19Å; E82-R156 PolarHBondContact OE1-NH2 2.68Å; E82-R156 IonicContact OE2-CZ 2.72Å; E82-R156 IonicContact OE2-NH1 2.66Å; E82-R156 IonicContact OE2-NH2 3.05Å; E82-R156 PolarHBondContact OE2-NH2 2.86Å
83G91Very high95Very high27 Ų2727.1 Ų27.128%0.27813%0.133SC..THydrogen-bonded Turntrans87.2-0.9-176.800000114.9M81 K116 Y117M81-G83 PolarHBondContact O-N 3.02Å; G83-K116 WeakPolarHBondContact O-CA 3.44Å; G83-Y117 PolarHBondContact O-N 3.28Å
84Y91.1Very high95.2Very high67 Ų6726.5 Ų26.526%0.26313%0.131SC..EExtended strand (participates in β ladder)trans-96.5142.3176-63.3-87000111.5L80 M81 E82 G113 E115 K116L80-Y84 WeakPolarHBondContact CA-O 3.46Å; M81-Y84 PolarHBondContact N-O 2.79Å; M81-Y84 PolarHBondContact O-N 2.91Å; E82-Y84 HydrophobicContact CB-CD2 4.39Å; Y84-G113 WeakPolarHBondContact CD1-O 3.34Å; Y84-E115 VanDerWaalsContact CD1-C 3.47Å; Y84-E115 WeakPolarHBondContact CD1-O 3.44Å; Y84-E115 VanDerWaalsContact CE1-C 3.46Å; Y84-K116 HydrophobicContact CE1-CG 4.11Å; Y84-K116 HydrophobicContact CE2-CG 4.34Å
85K94.6Very high95.2Very high13 Ų1326 Ų266%0.05713%0.13CC..EExtended strand (participates in β ladder)trans-73.9141.7167.3-177.8-178.2178-176.90108.5Y74 P78 L80 G113 Y117 H131 T133Y74-K85 PolarHBondContact OH-NZ 3.06Å; P78-K85 HydrophobicContact CB-CG 4.27Å; P78-K85 HydrophobicContact CG-CD 4.37Å; P78-K85 HydrophobicContact CG-CG 4.11Å; L80-K85 HydrophobicContact CD2-CB 4.35Å; K85-G113 PolarHBondContact O-N 3.32Å; K85-Y117 HydrophobicContact CB-CD2 3.87Å; K85-Y117 HydrophobicContact CB-CG 4.23Å; K85-Y117 HydrophobicContact CD-CD2 4.04Å; K85-Y117 HydrophobicContact CD-CE2 4.08Å; K85-Y117 HydrophobicContact CG-CD2 4.43Å; K85-H131 PolarHBondContact NZ-O 3.11Å; K85-T133 HydrophobicContact CB-CG2 4.34Å; K85-T133 HydrophobicContact CD-CG2 4.25Å; K85-T133 HydrophobicContact CG-CG2 3.89Å
86F94.7Very high95.2Very high2 Ų224.8 Ų24.81%0.00912%0.124CC..EExtended strand (participates in β ladder)trans-141158.8173.968.1-89.8000111.3F79 M81 L88 V110 R111 M112 F161 L222 L223F79-F86 AromaticContact CD1-CE1 3.68Å; F79-F86 HydrophobicContact CD1-CE1 3.68Å; F79-F86 AromaticContact CD1-CZ 3.66Å; F79-F86 HydrophobicContact CD1-CZ 3.66Å; F79-F86 HydrophobicContact CE1-CE1 4.42Å; F79-F86 HydrophobicContact CE1-CZ 4.4Å; M81-F86 HydrophobicContact CB-CD1 3.68Å; M81-F86 HydrophobicContact CB-CE1 3.73Å; F86-L88 HydrophobicContact CD2-CD2 4.07Å; F86-L88 HydrophobicContact CD2-CG 4.48Å; F86-L88 HydrophobicContact CE2-CD2 3.84Å; F86-L88 HydrophobicContact CE2-CG 4.19Å; F86-V110 HydrophobicContact CB-CG1 3.99Å; F86-V110 HydrophobicContact CD2-CG1 3.58Å; F86-V110 HydrophobicContact CE2-CG1 4.29Å; F86-V110 HydrophobicContact CG-CG1 3.95Å; F86-R111 CarbonylContact C-O 3.53Å; F86-R111 WeakPolarHBondContact CA-O 3.48Å; F86-R111 WeakPolarHBondContact CB-O 3.49Å; F86-M112 HydrophobicContact CB-CB 4.5Å; F86-M112 HydrophobicContact CB-CG 4.01Å; F86-F161 HydrophobicContact CE1-CE2 4.34Å; F86-F161 HydrophobicContact CE2-CD2 4.49Å; F86-F161 AromaticContact CE2-CE2 3.94Å; F86-F161 HydrophobicContact CE2-CE2 3.94Å; F86-F161 HydrophobicContact CE2-CZ 4.02Å; F86-F161 HydrophobicContact CZ-CD2 4.32Å; F86-F161 AromaticContact CZ-CE2 3.49Å; F86-F161 HydrophobicContact CZ-CE2 3.49Å; F86-F161 VanDerWaalsContact CZ-CE2 3.49Å; F86-F161 AromaticContact CZ-CZ 3.75Å; F86-F161 HydrophobicContact CZ-CZ 3.75Å; F86-L222 WeakPolarHBondContact O-CD1 3.42Å; F86-L223 HydrophobicContact CE2-CD1 4.4Å; F86-L223 HydrophobicContact CZ-CD1 4.35Å
87D95.6Very high95.3Very high2 Ų222.9 Ų22.91%0.01111%0.114CC..EExtended strand (participates in β ladder)trans-118.8164.3165.675.157.4000110.8V110 R111 T133 L222D87-V110 WeakPolarHBondContact O-CA 3.41Å; D87-R111 PolarHBondContact N-O 2.99Å; D87-R111 PolarHBondContact O-N 3.11Å; D87-R111 IonicContact OD1-CZ 2.8Å; D87-R111 IonicContact OD1-NE 3.43Å; D87-R111 PolarHBondContact OD1-NE 2.87Å; D87-R111 IonicContact OD1-NH2 2.61Å; D87-R111 PolarHBondContact OD1-NH2 2.97Å; D87-R111 IonicContact OD2-CZ 3.84Å; D87-R111 IonicContact OD2-NE 2.71Å; D87-R111 PolarHBondContact OD2-NE 2.94Å; D87-R111 IonicContact OD2-NH2 2.69Å; D87-R111 PolarHBondContact OD2-NH2 2.94Å; D87-R111 VanDerWaalsContact OD2-NH2 3.09Å; D87-T133 WeakPolarHBondContact OD2-CB 3.46Å; D87-T133 PolarHBondContact OD2-OG1 2.8Å; D87-L222 HydrophobicContact CB-CD1 4.32Å
88L96.9Very high95Very high0 Ų021.4 Ų21.40%011%0.111CC..EExtended strand (participates in β ladder)trans-109.6127176.7-58.1178.1000109.7F86 I90 V110 I158 F161 F175 F219 D220 I221 L223F86-L88 HydrophobicContact CD2-CD2 4.07Å; F86-L88 HydrophobicContact CD2-CG 4.48Å; F86-L88 HydrophobicContact CE2-CD2 3.84Å; F86-L88 HydrophobicContact CE2-CG 4.19Å; L88-I90 HydrophobicContact CB-CG1 4.25Å; L88-V110 HydrophobicContact CD2-CB 4.32Å; L88-V110 HydrophobicContact CD2-CG1 4.23Å; L88-V110 HydrophobicContact CD2-CG2 3.61Å; L88-I158 HydrophobicContact CD2-CG1 4.42Å; L88-F161 HydrophobicContact CD1-CE1 4.35Å; L88-F161 HydrophobicContact CD2-CD1 4.21Å; L88-F161 HydrophobicContact CD2-CE1 4.35Å; L88-F175 HydrophobicContact CD1-CE2 3.7Å; L88-F175 HydrophobicContact CD1-CZ 3.75Å; L88-F219 VanDerWaalsContact O-O 3.14Å; L88-D220 WeakPolarHBondContact O-CA 3.46Å; L88-I221 HydrophobicContact CB-CB 4.42Å; L88-I221 PolarHBondContact N-O 3.14Å; L88-I221 PolarHBondContact O-N 3.43Å; L88-L223 HydrophobicContact CD1-CD1 4.03Å; L88-L223 HydrophobicContact CD1-CD2 4.21Å; L88-L223 HydrophobicContact CD1-CG 4Å
89R97.3Very high94.8Very high22 Ų2224.6 Ų24.68%0.08313%0.132CC..EExtended strand (participates in β ladder)trans-96.5107.7163.817257.856.870.8-3.5108.8Y91 G108 L109 F219 D220 N235R89-Y91 HydrophobicContact CG-CE1 4.5Å; R89-Y91 HydrophobicContact CG-CE2 4.03Å; R89-G108 VanDerWaalsContact O-CA 3.31Å; R89-G108 WeakPolarHBondContact O-CA 3.43Å; R89-L109 HydrophobicContact CB-CB 4.1Å; R89-L109 PolarHBondContact N-O 3.3Å; R89-L109 PolarHBondContact O-N 2.64Å; R89-F219 WeakPolarHBondContact CA-O 3.3Å; R89-D220 IonicContact CZ-OD1 2.97Å; R89-D220 IonicContact CZ-OD2 3.55Å; R89-D220 IonicContact NE-OD1 3.45Å; R89-D220 PolarHBondContact NE-OD1 3.42Å; R89-D220 IonicContact NH2-OD1 3.59Å; R89-D220 PolarHBondContact NH2-OD1 2.94Å; R89-D220 IonicContact NH2-OD2 2.59Å; R89-D220 PolarHBondContact NH2-OD2 3.45Å; R89-N235 PolarHBondContact NH2-ND2 2.77Å; R89-N235 VanDerWaalsContact NH2-ND2 3.19Å
90I98Very high94.8Very high0 Ų023.5 Ų23.50%013%0.127CC..EExtended strand (participates in β ladder)trans-106.4135.8176.9-51.9-167.3000109.4L88 I92 L104 I158 I179 F219 I221L88-I90 HydrophobicContact CB-CG1 4.25Å; I90-I92 HydrophobicContact CG2-CD1 3.92Å; I90-L104 HydrophobicContact CG2-CD1 4.32Å; I90-L104 HydrophobicContact CG2-CG 4.27Å; I90-I158 HydrophobicContact CD1-CD1 4.33Å; I90-I158 HydrophobicContact CG1-CD1 3.76Å; I90-I179 HydrophobicContact CD1-CD1 3.85Å; I90-I179 HydrophobicContact CD1-CG1 4.22Å; I90-I179 HydrophobicContact CD1-CG2 3.49Å; I90-I179 VanDerWaalsContact CD1-CG2 3.49Å; I90-F219 HydrophobicContact CB-CB 4.46Å; I90-F219 PolarHBondContact N-O 2.92Å; I90-F219 PolarHBondContact O-N 3.33Å; I90-I221 HydrophobicContact CD1-CD1 3.95Å; I90-I221 HydrophobicContact CG1-CD1 4.42Å
91Y98.5Very high94.9Very high0 Ų020.8 Ų20.80%011%0.113CC..EExtended strand (participates in β ladder)trans-97.5124.5180-66-83.6000110.9R89 Y105 V216 L217 P238 F240 V250 V254R89-Y91 HydrophobicContact CG-CE1 4.5Å; R89-Y91 HydrophobicContact CG-CE2 4.03Å; Y91-Y105 VanDerWaalsContact O-CB 3.31Å; Y91-Y105 WeakPolarHBondContact O-CB 3.49Å; Y91-Y105 PolarHBondContact O-N 3.14Å; Y91-V216 HydrophobicContact CD1-CG1 4.26Å; Y91-L217 WeakPolarHBondContact CA-O 3.42Å; Y91-P238 HydrophobicContact CE1-CB 4.17Å; Y91-P238 HydrophobicContact CE1-CG 4.33Å; Y91-F240 HydrophobicContact CE1-CE1 4.1Å; Y91-V250 HydrophobicContact CD2-CG1 4.45Å; Y91-V250 HydrophobicContact CE2-CG1 4.04Å; Y91-V254 HydrophobicContact CD1-CG1 4.03Å; Y91-V254 HydrophobicContact CD1-CG2 4.33Å; Y91-V254 HydrophobicContact CD2-CG2 3.64Å; Y91-V254 HydrophobicContact CE2-CG2 4.25Å; Y91-V254 HydrophobicContact CG-CG1 4.04Å; Y91-V254 HydrophobicContact CG-CG2 3.69Å
92I98.6Very high95.2Very high0 Ų020.8 Ų20.80%011%0.113CC..EExtended strand (participates in β ladder)trans-117.2128.5-180-53.8-55.2000108.6I90 V94 I102 F103 L104 V183 L187 V216 L217 F219I90-I92 HydrophobicContact CG2-CD1 3.92Å; I92-V94 HydrophobicContact CG2-CG2 4.46Å; I92-I102 HydrophobicContact CG2-CG2 3.57Å; I92-F103 CarbonylContact C-O 3.49Å; I92-F103 WeakPolarHBondContact CA-O 3.22Å; I92-L104 HydrophobicContact CD1-CB 4Å; I92-L104 HydrophobicContact CD1-CD1 4.14Å; I92-L104 HydrophobicContact CD1-CG 3.97Å; I92-V183 HydrophobicContact CB-CG1 4.37Å; I92-V183 HydrophobicContact CD1-CB 4.36Å; I92-V183 HydrophobicContact CD1-CG1 3.77Å; I92-V183 HydrophobicContact CD1-CG2 3.76Å; I92-V183 HydrophobicContact CG1-CG1 3.73Å; I92-V183 HydrophobicContact CG1-CG2 4.06Å; I92-V183 HydrophobicContact CG2-CG1 3.75Å; I92-L187 HydrophobicContact CG2-CD1 4.08Å; I92-V216 CarbonylContact O-C 3.55Å; I92-V216 WeakPolarHBondContact O-CA 3.4Å; I92-L217 HydrophobicContact CB-CB 4.4Å; I92-L217 PolarHBondContact N-O 3.24Å; I92-L217 PolarHBondContact O-N 2.99Å; I92-F219 HydrophobicContact CB-CD2 4Å; I92-F219 HydrophobicContact CB-CE2 3.91Å; I92-F219 HydrophobicContact CG1-CD2 3.4Å; I92-F219 VanDerWaalsContact CG1-CD2 3.4Å; I92-F219 HydrophobicContact CG1-CE2 3.65Å; I92-F219 HydrophobicContact CG1-CG 4.04Å; I92-F219 HydrophobicContact CG1-CZ 4.45Å; I92-F219 HydrophobicContact CG2-CE2 4.4Å
93L98.6Very high95.7Very high0 Ų015.8 Ų15.80%09%0.089CC..EExtended strand (participates in β ladder)trans-103.2124.1173.4170.868.6000109.2T95 F103 F214 E215 V216 A258 L261 Y338L93-T95 HydrophobicContact CD1-CG2 4.2Å; L93-T95 HydrophobicContact CD2-CG2 3.72Å; L93-T95 HydrophobicContact CG-CG2 3.72Å; L93-F103 HydrophobicContact CB-CB 4.21Å; L93-F103 PolarHBondContact N-O 2.99Å; L93-F103 PolarHBondContact O-N 3.29Å; L93-F214 HydrophobicContact CD1-CD2 4.1Å; L93-E215 WeakPolarHBondContact CA-O 3.32Å; L93-V216 HydrophobicContact CD1-CG2 3.93Å; L93-A258 HydrophobicContact CD1-CB 4.15Å; L93-A258 HydrophobicContact CD2-CB 3.83Å; L93-L261 HydrophobicContact CD2-CB 4.28Å; L93-L261 HydrophobicContact CD2-CD1 3.79Å; L93-Y338 HydrophobicContact CB-CD1 4.27Å; L93-Y338 HydrophobicContact CB-CE1 3.55Å; L93-Y338 HydrophobicContact CD2-CE1 4.49Å; L93-Y338 HydrophobicContact CD2-CE2 4.31Å
94V98.3Very high96Very high22 Ų2214.5 Ų14.513%0.1338%0.076CC..EExtended strand (participates in β ladder)trans-107.3113169.9-1770000107.7I92 L100 R101 L187 F214 E215 L217I92-V94 HydrophobicContact CG2-CG2 4.46Å; V94-L100 HydrophobicContact CG1-CD1 4.28Å; V94-R101 WeakPolarHBondContact CA-O 3.33Å; V94-L187 HydrophobicContact CG2-CD1 3.68Å; V94-L187 HydrophobicContact CG2-CD2 4.3Å; V94-F214 CarbonylContact O-C 3.52Å; V94-F214 WeakPolarHBondContact O-CA 3.39Å; V94-F214 WeakPolarHBondContact O-CB 3.4Å; V94-E215 PolarHBondContact N-O 2.85Å; V94-E215 PolarHBondContact O-N 2.93Å; V94-L217 HydrophobicContact CG2-CD1 4.19Å
95T96.4Very high96.4Very high6 Ų611.9 Ų11.94%0.0377%0.066CC..EExtended strand (participates in β ladder)trans-95.8-13-177.464.50000113.2L93 R101 F103 S211 L262 R327L93-T95 HydrophobicContact CD1-CG2 4.2Å; L93-T95 HydrophobicContact CD2-CG2 3.72Å; L93-T95 HydrophobicContact CG-CG2 3.72Å; T95-R101 PolarHBondContact N-O 2.91Å; T95-R101 WeakPolarHBondContact OG1-CB 3.33Å; T95-F103 HydrophobicContact CG2-CD2 3.94Å; T95-F103 HydrophobicContact CG2-CE2 3.78Å; T95-F103 WeakPolarHBondContact OG1-CE2 3.5Å; T95-S211 WeakPolarHBondContact O-CB 3.01Å; T95-S211 PolarHBondContact O-OG 2.74Å; T95-L262 HydrophobicContact CG2-CD2 3.98Å; T95-R327 PolarHBondContact OG1-NH2 2.98Å
96S94.8Very high96.5Very high3 Ų313.5 Ų13.52%0.0218%0.075CC..EExtended strand (participates in β ladder)trans-165.2147.6-179178.20000110.5D98 P99 L100 R101S96-D98 PolarHBondContact OG-N 2.98Å; S96-D98 VanDerWaalsContact OG-N 3.14Å; S96-P99 CarbonylContact C-O 3.57Å; S96-P99 WeakPolarHBondContact CB-O 3.34Å; S96-P99 PolarHBondContact OG-O 3.41Å; S96-L100 CarbonylContact O-C 3.58Å; S96-L100 VanDerWaalsContact O-CA 3.31Å; S96-L100 WeakPolarHBondContact O-CA 3.1Å; S96-R101 PolarHBondContact O-N 3.02Å
97C93.8Very high96.5Very high11 Ų1114.4 Ų14.47%0.0748%0.08CC..EExtended strand (participates in β ladder)trans-106.4-8.5165.765.40000112.4P99 L100 V194C97-P99 VanDerWaalsContact C-C 3.44Å; C97-L100 PolarHBondContact O-N 3.43Å; C97-V194 HydrophobicContact CB-CG1 3.93Å
98D89.9Confident96.6Very high64 Ų6414.3 Ų14.334%0.3428%0.079SC..THydrogen-bonded Turntrans-142.986.4-178.9-161.42.3000111.2S96 L195 R199S96-D98 PolarHBondContact OG-N 2.98Å; S96-D98 VanDerWaalsContact OG-N 3.14Å; D98-L195 HydrophobicContact CB-CD1 3.6Å; D98-R199 IonicContact OD1-NH2 3.92Å; D98-R199 PolarHBondContact OD1-NH2 3.16Å; D98-R199 IonicContact OD2-CZ 2.71Å; D98-R199 VanDerWaalsContact OD2-CZ 3.28Å; D98-R199 IonicContact OD2-NE 3.38Å; D98-R199 PolarHBondContact OD2-NE 3.31Å; D98-R199 IonicContact OD2-NH2 2.98Å; D98-R199 PolarHBondContact OD2-NH2 3.04Å
99P91.9Very high96.5Very high74 Ų7414.6 Ų14.648%0.4818%0.081SC..THydrogen-bonded Turncis-74.5156.2-2.831.8-35.6000112.4S96 C97 R101S96-P99 CarbonylContact C-O 3.57Å; S96-P99 WeakPolarHBondContact CB-O 3.34Å; S96-P99 PolarHBondContact OG-O 3.41Å; C97-P99 VanDerWaalsContact C-C 3.44Å; P99-R101 PolarHBondContact O-N 2.81Å
100L95.4Very high96.4Very high13 Ų1313.6 Ų13.67%0.0688%0.077CC..EExtended strand (participates in β ladder)trans-62128.7176.4177.460.5000110.9V94 S96 C97 I102 E191 Y342V94-L100 HydrophobicContact CG1-CD1 4.28Å; S96-L100 CarbonylContact O-C 3.58Å; S96-L100 VanDerWaalsContact O-CA 3.31Å; S96-L100 WeakPolarHBondContact O-CA 3.1Å; C97-L100 PolarHBondContact O-N 3.43Å; L100-I102 HydrophobicContact CD1-CD1 4.02Å; L100-I102 HydrophobicContact CD1-CG1 3.8Å; L100-I102 HydrophobicContact CD2-CD1 3.92Å; L100-I102 HydrophobicContact CG-CD1 3.96Å; L100-I102 HydrophobicContact CG-CG1 3.99Å; L100-E191 WeakPolarHBondContact CD1-OE2 3.36Å; L100-E191 HydrophobicContact CD2-CB 4.4Å; L100-E191 HydrophobicContact CD2-CG 4.2Å; L100-Y342 HydrophobicContact CB-CD1 4.05Å; L100-Y342 HydrophobicContact CB-CE1 3.78Å; L100-Y342 HydrophobicContact CD2-CD1 4.02Å; L100-Y342 HydrophobicContact CD2-CE1 3.98Å; L100-Y342 HydrophobicContact CG-CD1 3.75Å; L100-Y342 HydrophobicContact CG-CE1 3.91Å; L100-Y342 VanDerWaalsContact O-CD1 3.26Å; L100-Y342 WeakPolarHBondContact O-CD1 3.12Å; L100-Y342 WeakPolarHBondContact O-CE1 3.35Å
101R96.5Very high96Very high6 Ų614.8 Ų14.82%0.0238%0.082CC..EExtended strand (participates in β ladder)trans-135.6123.8175.8-59.7-169.681.971-0.1110.8V94 T95 S96 P99 F103 R327 E328 E331 Y342V94-R101 WeakPolarHBondContact CA-O 3.33Å; T95-R101 PolarHBondContact N-O 2.91Å; T95-R101 WeakPolarHBondContact OG1-CB 3.33Å; S96-R101 PolarHBondContact O-N 3.02Å; P99-R101 PolarHBondContact O-N 2.81Å; R101-F103 HydrophobicContact CB-CE2 3.97Å; R101-R327 VanDerWaalsContact CD-CZ 3.41Å; R101-R327 VanDerWaalsContact CD-NH2 3.35Å; R101-E328 IonicContact NH1-OE1 2.68Å; R101-E331 IonicContact CZ-OE1 3.28Å; R101-E331 IonicContact CZ-OE2 3.88Å; R101-E331 VanDerWaalsContact NE-CD 3.32Å; R101-E331 IonicContact NE-OE1 3.02Å; R101-E331 PolarHBondContact NE-OE1 2.87Å; R101-E331 IonicContact NE-OE2 3.99Å; R101-E331 PolarHBondContact NE-OE2 3.35Å; R101-E331 IonicContact NH2-OE2 2.98Å; R101-E331 PolarHBondContact NH2-OE2 3.47Å; R101-Y342 WeakPolarHBondContact CA-O 3.49Å
102I98.5Very high95.6Very high0 Ų015.4 Ų15.40%09%0.085CC..EExtended strand (participates in β ladder)trans-129.3129.1-172.1-50.3168.7000109.6I92 L100 V183 V184 L187 I341 Y342I92-I102 HydrophobicContact CG2-CG2 3.57Å; L100-I102 HydrophobicContact CD1-CD1 4.02Å; L100-I102 HydrophobicContact CD1-CG1 3.8Å; L100-I102 HydrophobicContact CD2-CD1 3.92Å; L100-I102 HydrophobicContact CG-CD1 3.96Å; L100-I102 HydrophobicContact CG-CG1 3.99Å; I102-V183 HydrophobicContact CG2-CG1 4.12Å; I102-V184 HydrophobicContact CD1-CG2 4.43Å; I102-L187 HydrophobicContact CB-CD1 4.32Å; I102-L187 HydrophobicContact CD1-CB 3.7Å; I102-L187 HydrophobicContact CD1-CD1 3.54Å; I102-L187 HydrophobicContact CD1-CG 4.26Å; I102-L187 HydrophobicContact CG1-CD1 3.78Å; I102-L187 HydrophobicContact CG2-CD1 3.55Å; I102-I341 HydrophobicContact CB-CD1 4.49Å; I102-I341 HydrophobicContact CB-CG1 3.99Å; I102-I341 HydrophobicContact CG2-CD1 3.72Å; I102-I341 HydrophobicContact CG2-CG1 3.7Å; I102-I341 WeakPolarHBondContact O-CG1 3.22Å; I102-I341 PolarHBondContact O-N 3.43Å; I102-Y342 HydrophobicContact CD1-CG 4.23Å; I102-Y342 PolarHBondContact N-O 3.29Å; I102-Y342 PolarHBondContact O-N 2.69Å
103F98.6Very high94.9Very high0 Ų015.5 Ų15.50%09%0.086CC..EExtended strand (participates in β ladder)trans-122.5131.7179-58.6-98.7000109.9I92 L93 T95 R101 L261 E331 L335 Y338 R339 R340I92-F103 CarbonylContact C-O 3.49Å; I92-F103 WeakPolarHBondContact CA-O 3.22Å; L93-F103 HydrophobicContact CB-CB 4.21Å; L93-F103 PolarHBondContact N-O 2.99Å; L93-F103 PolarHBondContact O-N 3.29Å; T95-F103 HydrophobicContact CG2-CD2 3.94Å; T95-F103 HydrophobicContact CG2-CE2 3.78Å; T95-F103 WeakPolarHBondContact OG1-CE2 3.5Å; R101-F103 HydrophobicContact CB-CE2 3.97Å; F103-L261 HydrophobicContact CD1-CD1 4.08Å; F103-L261 HydrophobicContact CE1-CD1 4.45Å; F103-L261 HydrophobicContact CE1-CD2 4.41Å; F103-L261 HydrophobicContact CG-CD1 4.3Å; F103-E331 HydrophobicContact CZ-CG 4.29Å; F103-E331 WeakPolarHBondContact CZ-OE2 3.45Å; F103-L335 HydrophobicContact CD1-CD2 3.78Å; F103-L335 HydrophobicContact CE1-CD2 3.79Å; F103-Y338 HydrophobicContact CB-CD1 3.67Å; F103-Y338 HydrophobicContact CB-CE1 4.38Å; F103-Y338 HydrophobicContact CB-CG 4.19Å; F103-R339 CarbonylContact C-O 3.57Å; F103-R339 VanDerWaalsContact CA-O 3.31Å; F103-R339 WeakPolarHBondContact CA-O 3.31Å; F103-R340 HydrophobicContact CD1-CB 3.91Å; F103-R340 HydrophobicContact CD1-CG 4.4Å; F103-R340 HydrophobicContact CE1-CB 3.76Å; F103-R340 HydrophobicContact CE1-CG 4.03Å; F103-R340 HydrophobicContact CZ-CG 4.33Å
104L98.5Very high94.1Very high0 Ų015.8 Ų15.80%09%0.088CC..EExtended strand (participates in β ladder)trans-98.9132.6173.8177.3147.7000109.1I90 I92 W176 I179 Y338 R339 I341I90-L104 HydrophobicContact CG2-CD1 4.32Å; I90-L104 HydrophobicContact CG2-CG 4.27Å; I92-L104 HydrophobicContact CD1-CB 4Å; I92-L104 HydrophobicContact CD1-CD1 4.14Å; I92-L104 HydrophobicContact CD1-CG 3.97Å; L104-W176 HydrophobicContact CD1-CE3 4.22Å; L104-W176 HydrophobicContact CD1-CZ3 4.11Å; L104-W176 HydrophobicContact CD2-CE3 3.8Å; L104-W176 HydrophobicContact CD2-CH2 4.17Å; L104-W176 HydrophobicContact CD2-CZ3 3.43Å; L104-W176 VanDerWaalsContact CD2-CZ3 3.43Å; L104-W176 HydrophobicContact CG-CZ3 4.28Å; L104-I179 HydrophobicContact CD1-CG2 3.66Å; L104-Y338 CarbonylContact O-C 3.51Å; L104-Y338 WeakPolarHBondContact O-CA 3.38Å; L104-R339 PolarHBondContact N-O 3.44Å; L104-R339 PolarHBondContact O-N 2.86Å; L104-I341 HydrophobicContact CB-CD1 4.14Å; L104-I341 HydrophobicContact CB-CG1 4.46Å; L104-I341 HydrophobicContact CB-CG2 3.74Å
105Y98.3Very high93.5Very high12 Ų1217.2 Ų17.25%0.0479%0.093CC..EExtended strand (participates in β ladder)trans-81.7127.2172.1-161.1-111.4000109.7Y91 D107 G253 V254 N257 N337 Y338Y91-Y105 VanDerWaalsContact O-CB 3.31Å; Y91-Y105 WeakPolarHBondContact O-CB 3.49Å; Y91-Y105 PolarHBondContact O-N 3.14Å; Y105-D107 HydrophobicContact CD1-CB 4Å; Y105-D107 WeakPolarHBondContact CD1-O 3.46Å; Y105-D107 HydrophobicContact CE1-CB 3.84Å; Y105-D107 PolarHBondContact O-N 2.7Å; Y105-G253 WeakPolarHBondContact OH-CA 3.06Å; Y105-V254 HydrophobicContact CD1-CG2 3.41Å; Y105-V254 VanDerWaalsContact CD1-CG2 3.41Å; Y105-V254 HydrophobicContact CD2-CG2 4.22Å; Y105-V254 HydrophobicContact CE1-CG2 3.54Å; Y105-V254 HydrophobicContact CE2-CG2 4.31Å; Y105-V254 HydrophobicContact CG-CG2 3.79Å; Y105-V254 PolarHBondContact OH-N 3.28Å; Y105-N257 HydrophobicContact CE2-CB 4.45Å; Y105-N337 HydrophobicContact CD2-CB 4.37Å; Y105-N337 HydrophobicContact CE2-CB 3.67Å; Y105-Y338 AromaticContact CD2-CD1 3.94Å; Y105-Y338 HydrophobicContact CD2-CD1 3.94Å; Y105-Y338 AromaticContact CD2-CD2 3.69Å; Y105-Y338 HydrophobicContact CD2-CD2 3.69Å; Y105-Y338 AromaticContact CD2-CE1 3.84Å; Y105-Y338 HydrophobicContact CD2-CE1 3.84Å; Y105-Y338 AromaticContact CD2-CE2 3.57Å; Y105-Y338 HydrophobicContact CD2-CE2 3.57Å; Y105-Y338 AromaticContact CD2-CG 3.87Å; Y105-Y338 HydrophobicContact CD2-CG 3.87Å; Y105-Y338 AromaticContact CD2-CZ 3.65Å; Y105-Y338 HydrophobicContact CE2-CD2 4.16Å; Y105-Y338 HydrophobicContact CE2-CE2 4.05Å; Y105-Y338 HydrophobicContact CG-CD1 4.49Å; Y105-Y338 HydrophobicContact CG-CE1 4.22Å
106N96.4Very high93.2Very high46 Ų4622.9 Ų22.925%0.24612%0.117CC..EExtended strand (participates in β ladder)trans-75.917.7-176.1-58.7-45.9000113.5N337N106-N337 WeakPolarHBondContact CB-OD1 3.35Å; N106-N337 PolarHBondContact N-O 3.44Å; N106-N337 PolarHBondContact ND2-O 3.46Å
107D96.6Very high93.2Very high21 Ų2123.7 Ų23.711%0.11212%0.12CC..EExtended strand (participates in β ladder)trans-143.4177170.3-151-16.4000110Y105 I158 S159Y105-D107 HydrophobicContact CD1-CB 4Å; Y105-D107 WeakPolarHBondContact CD1-O 3.46Å; Y105-D107 HydrophobicContact CE1-CB 3.84Å; Y105-D107 PolarHBondContact O-N 2.7Å; D107-I158 WeakPolarHBondContact OD1-CA 3.28Å; D107-I158 PolarHBondContact OD1-N 3.27Å; D107-S159 PolarHBondContact OD1-N 3.21Å; D107-S159 PolarHBondContact OD1-OG 2.94Å; D107-S159 PolarHBondContact OD2-OG 2.89Å
108G96.1Very high93.1Very high0 Ų028.6 Ų28.60%014%0.142CC..EExtended strand (participates in β ladder)trans175.1-157.7-178.600000110.7R89 I158R89-G108 VanDerWaalsContact O-CA 3.31Å; R89-G108 WeakPolarHBondContact O-CA 3.43Å; G108-I158 PolarHBondContact O-N 2.9Å
109L95.1Very high93.2Very high7 Ų728.8 Ų28.84%0.03715%0.148CC..EExtended strand (participates in β ladder)trans-119.5130.4-179.5-52.2172.6000110R89 K155 L246 V250R89-L109 HydrophobicContact CB-CB 4.1Å; R89-L109 PolarHBondContact N-O 3.3Å; R89-L109 PolarHBondContact O-N 2.64Å; L109-K155 HydrophobicContact CD2-CD 4.32Å; L109-L246 HydrophobicContact CD2-CG 4.34Å; L109-V250 HydrophobicContact CD2-CB 4.2Å; L109-V250 HydrophobicContact CD2-CG1 4.26Å; L109-V250 HydrophobicContact CD2-CG2 4.18Å
110V94.7Very high93.1Very high0 Ų025.7 Ų25.70%013%0.128CC..EExtended strand (participates in β ladder)trans-94.3123.4165.7-174.60000107.7M81 F86 D87 L88 K155 R156 I158 F161M81-V110 HydrophobicContact CE-CG1 3.96Å; F86-V110 HydrophobicContact CB-CG1 3.99Å; F86-V110 HydrophobicContact CD2-CG1 3.58Å; F86-V110 HydrophobicContact CE2-CG1 4.29Å; F86-V110 HydrophobicContact CG-CG1 3.95Å; D87-V110 WeakPolarHBondContact O-CA 3.41Å; L88-V110 HydrophobicContact CD2-CB 4.32Å; L88-V110 HydrophobicContact CD2-CG1 4.23Å; L88-V110 HydrophobicContact CD2-CG2 3.61Å; V110-K155 VanDerWaalsContact O-CA 3.31Å; V110-K155 WeakPolarHBondContact O-CA 3.46Å; V110-R156 HydrophobicContact CB-CB 4.33Å; V110-R156 PolarHBondContact N-O 2.68Å; V110-R156 PolarHBondContact O-N 2.85Å; V110-I158 HydrophobicContact CG2-CG1 4.05Å; V110-F161 HydrophobicContact CG2-CB 3.76Å; V110-F161 HydrophobicContact CG2-CG 4.23Å
111R91.4Very high92.8Very high25 Ų2528.2 Ų28.29%0.09414%0.141CC..EExtended strand (participates in β ladder)trans-112.7109.9-179.2-61.1-179.4-65.9-175.2-1.7109.3F86 D87 D220F86-R111 CarbonylContact C-O 3.53Å; F86-R111 WeakPolarHBondContact CA-O 3.48Å; F86-R111 WeakPolarHBondContact CB-O 3.49Å; D87-R111 PolarHBondContact N-O 2.99Å; D87-R111 PolarHBondContact O-N 3.11Å; D87-R111 IonicContact OD1-CZ 2.8Å; D87-R111 IonicContact OD1-NE 3.43Å; D87-R111 PolarHBondContact OD1-NE 2.87Å; D87-R111 IonicContact OD1-NH2 2.61Å; D87-R111 PolarHBondContact OD1-NH2 2.97Å; D87-R111 IonicContact OD2-CZ 3.84Å; D87-R111 IonicContact OD2-NE 2.71Å; D87-R111 PolarHBondContact OD2-NE 2.94Å; D87-R111 IonicContact OD2-NH2 2.69Å; D87-R111 PolarHBondContact OD2-NH2 2.94Å; D87-R111 VanDerWaalsContact OD2-NH2 3.09Å; R111-D220 IonicContact CZ-OD2 2.83Å; R111-D220 IonicContact NH1-OD2 2.67Å; R111-D220 VanDerWaalsContact NH2-CG 3.31Å; R111-D220 IonicContact NH2-OD1 3.3Å; R111-D220 IonicContact NH2-OD2 2.83Å; R111-D220 PolarHBondContact NH2-OD2 3.22Å
112M88.1Confident92.3Very high13 Ų1333.6 Ų33.66%0.06417%0.171CC..EExtended strand (participates in β ladder)trans-87.3150.9178-61.9-162.8-77.200111.6M81 F86 G153 S154M81-M112 HydrophobicContact CE-CE 4.17Å; M81-M112 HydrophobicContact CE-CG 3.6Å; M81-M112 HydrophobicContact CE-SD 3.14Å; M81-M112 WeakPolarHBondContact CE-SD 3.36Å; F86-M112 HydrophobicContact CB-CB 4.5Å; F86-M112 HydrophobicContact CB-CG 4.01Å; M112-G153 WeakPolarHBondContact CE-O 3.26Å; M112-S154 PolarHBondContact N-O 2.99Å
113G84.7Confident91.8Very high3 Ų337.5 Ų37.53%0.03120%0.203CC..EExtended strand (participates in β ladder)trans-69.5160.8161.200000111Y84 K85Y84-G113 WeakPolarHBondContact CD1-O 3.34Å; K85-G113 PolarHBondContact O-N 3.32Å
114T82.7Confident91.3Very high6 Ų637.8 Ų37.84%0.03720%0.204CC..EExtended strand (participates in β ladder)trans-93.6-8.2-178.851.60000113.7N138 N141 F144T114-N138 HydrophobicContact CG2-CB 3.76Å; T114-N138 WeakPolarHBondContact CG2-OD1 3.46Å; T114-N138 PolarHBondContact N-OD1 3.35Å; T114-N138 PolarHBondContact OG1-OD1 2.72Å; T114-N141 HydrophobicContact CG2-CB 4.16Å; T114-N141 PolarHBondContact OG1-ND2 3.5Å; T114-F144 HydrophobicContact CG2-CB 4.02Å; T114-F144 HydrophobicContact CG2-CD2 3.7Å; T114-F144 HydrophobicContact CG2-CG 4.35Å
115E85.8Confident90.6Very high52 Ų5239.1 Ų39.124%0.24321%0.211CC..EExtended strand (participates in β ladder)trans-125.5146.7178.4-71.6175.1-153.300111Y84 Y117 M130 N141Y84-E115 VanDerWaalsContact CD1-C 3.47Å; Y84-E115 WeakPolarHBondContact CD1-O 3.44Å; Y84-E115 VanDerWaalsContact CE1-C 3.46Å; E115-Y117 PolarHBondContact O-N 2.98Å; E115-M130 HydrophobicContact CB-CB 3.99Å; E115-N141 PolarHBondContact OE1-ND2 3.42Å
116K90.3Very high89.9Confident125 Ų12544.4 Ų44.454%0.54325%0.245SC..EExtended strand (participates in β ladder)trans-60.3135179.3-75.2-172.5176.3179.40110.6G83 Y84 H118 M130G83-K116 WeakPolarHBondContact O-CA 3.44Å; Y84-K116 HydrophobicContact CE1-CG 4.11Å; Y84-K116 HydrophobicContact CE2-CG 4.34Å; K116-H118 PolarHBondContact O-N 3.27Å; K116-M130 WeakPolarHBondContact O-CE 3.45Å
117Y93.5Very high89.2Confident19 Ų1946.3 Ų46.38%0.07525%0.252CS..  trans-74.1126.1-175.9-177.9-99.5000111.7Y74 D76 P78 L80 G83 K85 E115 M130 H131Y74-Y117 WeakPolarHBondContact OH-CE2 3.31Å; D76-Y117 VanDerWaalsContact C-OH 3.25Å; D76-Y117 WeakPolarHBondContact CA-OH 3.29Å; D76-Y117 WeakPolarHBondContact O-CE1 3.41Å; D76-Y117 PolarHBondContact O-OH 3.48Å; P78-Y117 HydrophobicContact CG-CD1 4.05Å; P78-Y117 HydrophobicContact CG-CD2 4.4Å; P78-Y117 HydrophobicContact CG-CE1 3.76Å; P78-Y117 HydrophobicContact CG-CE2 4.15Å; P78-Y117 HydrophobicContact CG-CG 4.35Å; L80-Y117 HydrophobicContact CD1-CD1 4.08Å; L80-Y117 HydrophobicContact CD2-CD1 3.77Å; L80-Y117 HydrophobicContact CD2-CG 3.77Å; L80-Y117 HydrophobicContact CG-CD1 4.48Å; G83-Y117 PolarHBondContact O-N 3.28Å; K85-Y117 HydrophobicContact CB-CD2 3.87Å; K85-Y117 HydrophobicContact CB-CG 4.23Å; K85-Y117 HydrophobicContact CD-CD2 4.04Å; K85-Y117 HydrophobicContact CD-CE2 4.08Å; K85-Y117 HydrophobicContact CG-CD2 4.43Å; E115-Y117 PolarHBondContact O-N 2.98Å; Y117-M130 WeakPolarHBondContact CD2-O 3.37Å; Y117-H131 AromaticContact CE2-ND1 3.7Å
118H92.8Very high88.5Confident115 Ų11547.9 Ų47.953%0.53226%0.26SS..  trans-116147164-68.2-76.5000110.1K116 M130 H131K116-H118 PolarHBondContact O-N 3.27Å; H118-M130 HydrophobicContact CB-CE 4.32Å; H118-M130 HydrophobicContact CB-SD 4.17Å; H118-H131 PolarHBondContact O-CE1 3.13Å
119S91.1Very high87.6Confident68 Ų6851.9 Ų51.948%0.47628%0.276SS..  trans-59.7141.2176.4-70.80000110.7N121 N124S119-N121 PolarHBondContact O-N 3.01Å; S119-N121 PolarHBondContact O-ND2 3.23Å; S119-N124 PolarHBondContact O-ND2 3.3Å
120P90.3Very high87Confident8 Ų851.9 Ų51.95%0.05228%0.276CS..  trans-65126.6-174.325.8-35.4000111.5T40 L56 Y74 D76 N124 L125T40-P120 HydrophobicContact CG2-CB 3.84Å; T40-P120 HydrophobicContact CG2-CG 3.99Å; T40-P120 WeakPolarHBondContact OG1-CG 3.22Å; L56-P120 HydrophobicContact CD2-CB 4.5Å; Y74-P120 HydrophobicContact CD1-CG 3.91Å; Y74-P120 HydrophobicContact CE1-CG 3.9Å; D76-P120 HydrophobicContact CB-CG 4.06Å; P120-N124 WeakPolarHBondContact CA-OD1 3.48Å; P120-L125 HydrophobicContact CB-CD2 4.11Å
121N89.5Confident86.6Confident67 Ų6751.9 Ų51.936%0.35828%0.276SS..  trans-139.5170175.567.265000109.3S119 A123 N124 L125S119-N121 PolarHBondContact O-N 3.01Å; S119-N121 PolarHBondContact O-ND2 3.23Å; N121-A123 PolarHBondContact O-N 2.78Å; N121-A123 WeakPolarHBondContact OD1-CA 3.37Å; N121-A123 VanDerWaalsContact OD1-CB 3.32Å; N121-A123 WeakPolarHBondContact OD1-CB 3.49Å; N121-A123 PolarHBondContact OD1-N 3.09Å; N121-N124 PolarHBondContact N-OD1 2.81Å; N121-N124 PolarHBondContact ND2-ND2 2.97Å; N121-N124 PolarHBondContact O-N 2.53Å; N121-N124 VanDerWaalsContact O-N 3.1Å; N121-N124 PolarHBondContact O-OD1 3.49Å; N121-N124 PolarHBondContact OD1-N 2.68Å; N121-L125 WeakPolarHBondContact O-CG 3.25Å; N121-L125 PolarHBondContact O-N 3.12Å
122D85.8Confident86.2Confident119 Ų11951.1 Ų51.164%0.63627%0.274SS*.THydrogen-bonded Turntrans-64.2-17-170.6-56.9-33.9000113.8R58R58-D122 WeakPolarHBondContact CD-OD1 3.47Å; R58-D122 IonicContact NH1-OD1 3.07Å
123A87.7Confident85.8Confident81 Ų8150.9 Ų50.967%0.66927%0.273SS*.THydrogen-bonded Turntrans-87.6-21.4177.500000114.3N121N121-A123 PolarHBondContact O-N 2.78Å; N121-A123 WeakPolarHBondContact OD1-CA 3.37Å; N121-A123 VanDerWaalsContact OD1-CB 3.32Å; N121-A123 WeakPolarHBondContact OD1-CB 3.49Å; N121-A123 PolarHBondContact OD1-N 3.09Å
124N87.4Confident85.4Confident7 Ų752 Ų524%0.03728%0.278CS..THydrogen-bonded Turntrans-114.61.8-174.871.23.5000115.2S119 P120 N121 T126 Q127 M130 H131S119-N124 PolarHBondContact O-ND2 3.3Å; P120-N124 WeakPolarHBondContact CA-OD1 3.48Å; N121-N124 PolarHBondContact N-OD1 2.81Å; N121-N124 PolarHBondContact ND2-ND2 2.97Å; N121-N124 PolarHBondContact O-N 2.53Å; N121-N124 VanDerWaalsContact O-N 3.1Å; N121-N124 PolarHBondContact O-OD1 3.49Å; N121-N124 PolarHBondContact OD1-N 2.68Å; N124-T126 PolarHBondContact O-N 2.74Å; N124-T126 VanDerWaalsContact O-N 3.1Å; N124-Q127 WeakPolarHBondContact O-CB 3.48Å; N124-Q127 PolarHBondContact O-N 2.89Å; N124-M130 HydrophobicContact CB-SD 4.32Å; N124-H131 PolarHBondContact O-NE2 2.89Å
125L85Confident84.6Confident27 Ų2754.8 Ų54.814%0.14129%0.288CS..THydrogen-bonded Turntrans-58.1-28179.5-66.4172.9000114T40 L56 R58 P120 N121T40-L125 HydrophobicContact CG2-CD2 4.04Å; L56-L125 HydrophobicContact CB-CB 4.44Å; L56-L125 HydrophobicContact CB-CD2 3.77Å; L56-L125 HydrophobicContact CD2-CD2 4.41Å; R58-L125 HydrophobicContact CB-CD1 4.39Å; R58-L125 HydrophobicContact CG-CD1 3.9Å; R58-L125 HydrophobicContact CG-CD2 3.89Å; R58-L125 HydrophobicContact CG-CG 4.47Å; P120-L125 HydrophobicContact CB-CD2 4.11Å; N121-L125 WeakPolarHBondContact O-CG 3.25Å; N121-L125 PolarHBondContact O-N 3.12Å
126T83.1Confident83.4Confident123 Ų12353.3 Ų53.376%0.75528%0.284SS*.THydrogen-bonded Turntrans-86.2-11.8178.654.50000113.2N124 L128N124-T126 PolarHBondContact O-N 2.74Å; N124-T126 VanDerWaalsContact O-N 3.1Å; T126-L128 VanDerWaalsContact C-N 3.27Å; T126-L128 PolarHBondContact O-N 2.79Å
127Q82.6Confident82Confident86 Ų8648.7 Ų48.740%0.40227%0.266SS..  trans-80.274.4177.7-64.9-178.4-22.200110.1N124 Y129 M130N124-Q127 WeakPolarHBondContact O-CB 3.48Å; N124-Q127 PolarHBondContact O-N 2.89Å; Q127-Y129 VanDerWaalsContact C-N 3.26Å; Q127-Y129 PolarHBondContact O-N 2.86Å; Q127-M130 HydrophobicContact CB-CG 4.12Å; Q127-M130 WeakPolarHBondContact O-CG 3.35Å; Q127-M130 PolarHBondContact O-N 3.36Å
128L80.9Confident80.8Confident54 Ų5447.8 Ų47.828%0.28326%0.263SS..Hα-helixtrans-65.2-26.4-172.8-64.2-179000113.5L56 T126 M130 H131 L132L56-L128 HydrophobicContact CD1-CD2 4.1Å; T126-L128 VanDerWaalsContact C-N 3.27Å; T126-L128 PolarHBondContact O-N 2.79Å; L128-M130 VanDerWaalsContact C-N 3.3Å; L128-M130 PolarHBondContact O-N 3.1Å; L128-H131 PolarHBondContact O-N 3.37Å; L128-H131 VanDerWaalsContact O-N 3.08Å; L128-L132 HydrophobicContact CB-CD1 4.08Å; L128-L132 HydrophobicContact CB-CG 4.33Å; L128-L132 HydrophobicContact CD1-CD1 4.34Å; L128-L132 HydrophobicContact CD2-CD1 4.23Å; L128-L132 HydrophobicContact CD2-CG 4.48Å; L128-L132 HydrophobicContact CG-CD1 4.45Å; L128-L132 WeakPolarHBondContact O-CB 3.45Å; L128-L132 PolarHBondContact O-N 3.02Å
129Y77.9Confident79.4Confident84 Ų8446 Ų4633%0.32925%0.253SS..Hα-helixtrans-66.3-25.4-178.7-63.6-61.5000114.4Q127 V137 N138 N141Q127-Y129 VanDerWaalsContact C-N 3.26Å; Q127-Y129 PolarHBondContact O-N 2.86Å; Y129-V137 HydrophobicContact CD1-CG1 3.99Å; Y129-V137 HydrophobicContact CE1-CG1 3.86Å; Y129-V137 WeakPolarHBondContact CE1-O 3.44Å; Y129-N138 PolarHBondContact O-OD1 3.35Å; Y129-N141 HydrophobicContact CD1-CB 4.03Å; Y129-N141 WeakPolarHBondContact CD2-ND2 3.31Å; Y129-N141 HydrophobicContact CE1-CB 4Å; Y129-N141 HydrophobicContact CG-CB 4.48Å
130M82.7Confident78.1Confident7 Ų749.2 Ų49.23%0.03426%0.261CS..Hα-helixtrans-87-20.4171.465.116159.400113.1E115 K116 Y117 H118 N124 Q127 L128E115-M130 HydrophobicContact CB-CB 3.99Å; K116-M130 WeakPolarHBondContact O-CE 3.45Å; Y117-M130 WeakPolarHBondContact CD2-O 3.37Å; H118-M130 HydrophobicContact CB-CE 4.32Å; H118-M130 HydrophobicContact CB-SD 4.17Å; N124-M130 HydrophobicContact CB-SD 4.32Å; Q127-M130 HydrophobicContact CB-CG 4.12Å; Q127-M130 WeakPolarHBondContact O-CG 3.35Å; Q127-M130 PolarHBondContact O-N 3.36Å; L128-M130 VanDerWaalsContact C-N 3.3Å; L128-M130 PolarHBondContact O-N 3.1Å
131H86Confident77Confident1 Ų149.8 Ų49.81%0.00526%0.263CS..Hα-helixtrans-101.7-25.7-173.2-68-32.5000113.7L56 Y74 K85 Y117 H118 N124 L128L56-H131 HydrophobicContact CD1-CB 4.07Å; L56-H131 HydrophobicContact CD2-CB 4.13Å; Y74-H131 PolarHBondContact OH-ND1 3.19Å; K85-H131 PolarHBondContact NZ-O 3.11Å; Y117-H131 AromaticContact CE2-ND1 3.7Å; H118-H131 PolarHBondContact O-CE1 3.13Å; N124-H131 PolarHBondContact O-NE2 2.89Å; L128-H131 PolarHBondContact O-N 3.37Å; L128-H131 VanDerWaalsContact O-N 3.08Å
132L83.4Confident75.7Confident8 Ų855.9 Ų55.94%0.04229%0.289CS..  trans-112.7130.8179.2-54.1-175.4000110I42 I54 L128 N138I42-L132 HydrophobicContact CD1-CD2 4.15Å; I54-L132 HydrophobicContact CB-CD1 4.12Å; I54-L132 HydrophobicContact CB-CD2 4.49Å; I54-L132 HydrophobicContact CG2-CD1 4.15Å; I54-L132 HydrophobicContact CG2-CD2 3.71Å; L128-L132 HydrophobicContact CB-CD1 4.08Å; L128-L132 HydrophobicContact CB-CG 4.33Å; L128-L132 HydrophobicContact CD1-CD1 4.34Å; L128-L132 HydrophobicContact CD2-CD1 4.23Å; L128-L132 HydrophobicContact CD2-CG 4.48Å; L128-L132 HydrophobicContact CG-CD1 4.45Å; L128-L132 WeakPolarHBondContact O-CB 3.45Å; L128-L132 PolarHBondContact O-N 3.02Å; L132-N138 PolarHBondContact O-ND2 3.01Å
133T79.6Confident74.9Confident8 Ų854.8 Ų54.85%0.04928%0.284CS..  trans-102.3-1.4-176.644.30000112.5K85 D87 Y135K85-T133 HydrophobicContact CB-CG2 4.34Å; K85-T133 HydrophobicContact CD-CG2 4.25Å; K85-T133 HydrophobicContact CG-CG2 3.89Å; D87-T133 WeakPolarHBondContact OD2-CB 3.46Å; D87-T133 PolarHBondContact OD2-OG1 2.8Å; T133-Y135 PolarHBondContact O-N 2.83Å
134N76.4Confident73.5Confident26 Ų2651.9 Ų51.914%0.13926%0.256CS..  trans-59.4128.8-179.6-66.756.1000111S136 V137 N138N134-S136 VanDerWaalsContact C-N 3.27Å; N134-S136 PolarHBondContact O-N 3.34Å; N134-V137 HydrophobicContact CB-CG2 4.18Å; N134-V137 PolarHBondContact O-N 3.49Å; N134-V137 VanDerWaalsContact O-N 3.11Å; N134-N138 PolarHBondContact O-N 3.19Å; N134-N138 PolarHBondContact O-ND2 3.47Å
135Y65.3Low72.3Confident65 Ų6556.2 Ų56.226%0.25528%0.276SS..Hα-helixtrans-55.2-41.3176.4172.6-107.2000112.7T133 V137 N138 K139 F144 D243T133-Y135 PolarHBondContact O-N 2.83Å; Y135-V137 PolarHBondContact O-N 2.99Å; Y135-N138 PolarHBondContact O-N 2.94Å; Y135-K139 HydrophobicContact CD1-CD 4.22Å; Y135-K139 HydrophobicContact CD2-CB 4.21Å; Y135-K139 HydrophobicContact CE1-CB 4.4Å; Y135-K139 HydrophobicContact CE1-CD 3.84Å; Y135-K139 HydrophobicContact CE2-CB 3.89Å; Y135-K139 WeakPolarHBondContact O-CB 3.25Å; Y135-K139 VanDerWaalsContact O-CG 3.3Å; Y135-K139 WeakPolarHBondContact O-CG 3.32Å; Y135-K139 PolarHBondContact O-N 3.46Å; Y135-F144 HydrophobicContact CD2-CE2 4.14Å; Y135-F144 AromaticContact CD2-CZ 3.72Å; Y135-F144 HydrophobicContact CD2-CZ 3.72Å; Y135-F144 HydrophobicContact CE2-CE1 4.02Å; Y135-F144 HydrophobicContact CE2-CE2 4.38Å; Y135-F144 AromaticContact CE2-CZ 3.58Å; Y135-F144 HydrophobicContact CE2-CZ 3.58Å; Y135-D243 PolarHBondContact OH-OD2 2.91Å
136S59.2Low71.2Confident21 Ų2163 Ų6315%0.14730%0.3CS..Hα-helixtrans-59-31179.143.30000113.9M50 N134 H140M50-S136 VanDerWaalsContact C-OG 3.26Å; M50-S136 WeakPolarHBondContact CA-OG 3.42Å; M50-S136 WeakPolarHBondContact CB-OG 3.31Å; M50-S136 PolarHBondContact O-OG 3.27Å; N134-S136 VanDerWaalsContact C-N 3.27Å; N134-S136 PolarHBondContact O-N 3.34Å; S136-H140 PolarHBondContact O-CD2 3.32Å
137V61.8Low69.7Low28 Ų2865 Ų6517%0.1730%0.298CS..Hα-helixtrans-82.6-51.1176179.90000109.2Y129 N134 Y135 K139Y129-V137 HydrophobicContact CD1-CG1 3.99Å; Y129-V137 HydrophobicContact CE1-CG1 3.86Å; Y129-V137 WeakPolarHBondContact CE1-O 3.44Å; N134-V137 HydrophobicContact CB-CG2 4.18Å; N134-V137 PolarHBondContact O-N 3.49Å; N134-V137 VanDerWaalsContact O-N 3.11Å; Y135-V137 PolarHBondContact O-N 2.99Å; V137-K139 PolarHBondContact O-N 3.32Å
138N68.7Low68.2Low1 Ų168 Ų681%0.00531%0.313CS..Hα-helixtrans-73.3-27.5-171.5-75.2-78.3000114.3T114 Y129 L132 N134 Y135 H140 N141 F144T114-N138 HydrophobicContact CG2-CB 3.76Å; T114-N138 WeakPolarHBondContact CG2-OD1 3.46Å; T114-N138 PolarHBondContact N-OD1 3.35Å; T114-N138 PolarHBondContact OG1-OD1 2.72Å; Y129-N138 PolarHBondContact O-OD1 3.35Å; L132-N138 PolarHBondContact O-ND2 3.01Å; N134-N138 PolarHBondContact O-N 3.19Å; N134-N138 PolarHBondContact O-ND2 3.47Å; Y135-N138 PolarHBondContact O-N 2.94Å; N138-H140 PolarHBondContact O-N 2.85Å; N138-N141 WeakPolarHBondContact O-CB 3.41Å; N138-N141 PolarHBondContact O-N 3.06Å; N138-F144 HydrophobicContact CB-CD2 4.04Å; N138-F144 HydrophobicContact CB-CE2 4.3Å; N138-F144 WeakPolarHBondContact O-CB 3.47Å; N138-F144 WeakPolarHBondContact O-CD2 3.45Å
139K63.4Low66.7Low77 Ų7768.1 Ų68.134%0.33532%0.321SS..THydrogen-bonded Turntrans-60.6-18.2179.572.2-179.2-173.9173.90114.3Y135 V137Y135-K139 HydrophobicContact CD1-CD 4.22Å; Y135-K139 HydrophobicContact CD2-CB 4.21Å; Y135-K139 HydrophobicContact CE1-CB 4.4Å; Y135-K139 HydrophobicContact CE1-CD 3.84Å; Y135-K139 HydrophobicContact CE2-CB 3.89Å; Y135-K139 WeakPolarHBondContact O-CB 3.25Å; Y135-K139 VanDerWaalsContact O-CG 3.3Å; Y135-K139 WeakPolarHBondContact O-CG 3.32Å; Y135-K139 PolarHBondContact O-N 3.46Å; V137-K139 PolarHBondContact O-N 3.32Å
140H64.3Low65.5Low136 Ų13669.3 Ų69.363%0.6334%0.337SS*.THydrogen-bonded Turntrans-95.1-7.8179.2-65.1-64.8000113.1S136 N138S136-H140 PolarHBondContact O-CD2 3.32Å; N138-H140 PolarHBondContact O-N 2.85Å
141N66.2Low64.1Low20 Ų2073.9 Ų73.911%0.10736%0.361CS..SBendtrans-77.2139175.3-167.9-38.8000109.3T114 E115 Y129 N138 N143 F144T114-N141 HydrophobicContact CG2-CB 4.16Å; T114-N141 PolarHBondContact OG1-ND2 3.5Å; E115-N141 PolarHBondContact OE1-ND2 3.42Å; Y129-N141 HydrophobicContact CD1-CB 4.03Å; Y129-N141 WeakPolarHBondContact CD2-ND2 3.31Å; Y129-N141 HydrophobicContact CE1-CB 4Å; Y129-N141 HydrophobicContact CG-CB 4.48Å; N138-N141 WeakPolarHBondContact O-CB 3.41Å; N138-N141 PolarHBondContact O-N 3.06Å; N141-N143 PolarHBondContact O-N 3.47Å; N141-N143 WeakPolarHBondContact OD1-CB 3.36Å; N141-N143 PolarHBondContact OD1-N 2.69Å; N141-F144 WeakPolarHBondContact O-CB 3.18Å; N141-F144 PolarHBondContact O-N 3.19Å
142E62.9Low62.7Low194 Ų19482.5 Ų82.591%0.90739%0.394SS*.THydrogen-bonded Turntrans-60.6-29.2176.6-63.2-178.8174.800112.1F144E142-F144 PolarHBondContact O-N 2.91Å
143N67.9Low61.8Low97 Ų9782.4 Ų82.452%0.51940%0.395SS..THydrogen-bonded Turntrans-80.76176.7-62.7-35.9000113.6N141 E145N141-N143 PolarHBondContact O-N 3.47Å; N141-N143 WeakPolarHBondContact OD1-CB 3.36Å; N141-N143 PolarHBondContact OD1-N 2.69Å; N143-E145 PolarHBondContact O-N 2.72Å
144F59.5Low61.6Low19 Ų1982.6 Ų82.68%0.08340%0.397CS..  trans-74.299177.3-169.8-94.3000110.7T114 Y135 N138 N141 E142 R146 S154T114-F144 HydrophobicContact CG2-CB 4.02Å; T114-F144 HydrophobicContact CG2-CD2 3.7Å; T114-F144 HydrophobicContact CG2-CG 4.35Å; Y135-F144 HydrophobicContact CD2-CE2 4.14Å; Y135-F144 AromaticContact CD2-CZ 3.72Å; Y135-F144 HydrophobicContact CD2-CZ 3.72Å; Y135-F144 HydrophobicContact CE2-CE1 4.02Å; Y135-F144 HydrophobicContact CE2-CE2 4.38Å; Y135-F144 AromaticContact CE2-CZ 3.58Å; Y135-F144 HydrophobicContact CE2-CZ 3.58Å; N138-F144 HydrophobicContact CB-CD2 4.04Å; N138-F144 HydrophobicContact CB-CE2 4.3Å; N138-F144 WeakPolarHBondContact O-CB 3.47Å; N138-F144 WeakPolarHBondContact O-CD2 3.45Å; N141-F144 WeakPolarHBondContact O-CB 3.18Å; N141-F144 PolarHBondContact O-N 3.19Å; E142-F144 PolarHBondContact O-N 2.91Å; F144-R146 HydrophobicContact CD1-CG 3.67Å; F144-R146 HydrophobicContact CE1-CG 3.86Å; F144-R146 PolarHBondContact O-N 2.84Å; F144-R146 VanDerWaalsContact O-N 3.09Å; F144-S154 VanDerWaalsContact CE2-CB 3.49Å
145E61.8Low62.1Low99 Ų9982.5 Ų82.546%0.46340%0.395SS..  trans-73.5103.9177-67.5-174.1-179.100110.3N143 F147 S154N143-E145 PolarHBondContact O-N 2.72Å; E145-F147 PolarHBondContact O-N 2.88Å; E145-S154 PolarHBondContact O-N 2.87Å
146R61.5Low63.3Low170 Ų17079.9 Ų79.964%0.64239%0.385SS*.  trans-77.4-6.9173.3-63.3-173.8-178-1772.4113.4F144F144-R146 HydrophobicContact CD1-CG 3.67Å; F144-R146 HydrophobicContact CE1-CG 3.86Å; F144-R146 PolarHBondContact O-N 2.84Å; F144-R146 VanDerWaalsContact O-N 3.09Å
147F51.9Low64.9Low163 Ų16380 Ų8072%0.71539%0.385SS*.  trans-60.2138.5-170.6-82-79.1000111.8E145 A149 R152E145-F147 PolarHBondContact O-N 2.88Å; F147-A149 PolarHBondContact O-N 3.37Å; F147-R152 VanDerWaalsContact O-O 3.11Å
148E51.1Low66.5Low151 Ų15178.6 Ų78.671%0.70638%0.377SS*.  trans-85.510.7-175.9-61.8-172.3141.700113.1V150E148-V150 PolarHBondContact O-N 2.99Å
149A50Low67.7Low56 Ų5681.2 Ų81.246%0.46340%0.396SS..BIsolated β-bridgetrans-66.4123.8172.800000108F147 D151 R152F147-A149 PolarHBondContact O-N 3.37Å; A149-D151 PolarHBondContact O-N 2.81Å; A149-R152 HydrophobicContact CB-CB 4.17Å; A149-R152 CarbonylContact O-C 3.55Å; A149-R152 PolarHBondContact O-N 3.07Å
150V52.3Low69.2Low108 Ų10879.4 Ų79.466%0.65539%0.387SS*.THydrogen-bonded Turntrans-48.1-29.5-177.4177.90000112.4E148 W160E148-V150 PolarHBondContact O-N 2.99Å; V150-W160 PolarHBondContact O-NE1 2.92Å
151D54Low70.6Confident103 Ų10373 Ų7355%0.55136%0.357SS*.THydrogen-bonded Turntrans-105.6-3.2-177.2-57.7-37.2000114.9A149 R156 W160A149-D151 PolarHBondContact O-N 2.81Å; D151-R156 PolarHBondContact O-NH2 3.18Å; D151-W160 PolarHBondContact OD1-NE1 2.66Å
152R54.9Low72Confident182 Ų18272.4 Ų72.469%0.68735%0.354SS*.BIsolated β-bridgetrans-139.492.3-177.4-59.3-173.6-170.7-1772.8111.3F147 A149F147-R152 VanDerWaalsContact O-O 3.11Å; A149-R152 HydrophobicContact CB-CB 4.17Å; A149-R152 CarbonylContact O-C 3.55Å; A149-R152 PolarHBondContact O-N 3.07Å
153G64.5Low73.5Confident7 Ų767.6 Ų67.67%0.07233%0.331CS..SBendtrans-178.8146.8174.700000111.8M112 K155M112-G153 WeakPolarHBondContact CE-O 3.26Å; G153-K155 PolarHBondContact O-N 2.88Å
154S75.9Confident74.7Confident12 Ų1264.8 Ų64.88%0.08431%0.314CS..SBendtrans-68.80-176.2-53.50000114.7M112 F144 E145M112-S154 PolarHBondContact N-O 2.99Å; F144-S154 VanDerWaalsContact CE2-CB 3.49Å; E145-S154 PolarHBondContact O-N 2.87Å
155K86.3Confident76.4Confident24 Ų2463.9 Ų63.910%0.10431%0.31CS..EExtended strand (participates in β ladder)trans-133.5129.9174.4-166.1-170.9-66.1162.30109.5L109 V110 G153 Q244 L246 D247L109-K155 HydrophobicContact CD2-CD 4.32Å; V110-K155 VanDerWaalsContact O-CA 3.31Å; V110-K155 WeakPolarHBondContact O-CA 3.46Å; G153-K155 PolarHBondContact O-N 2.88Å; K155-Q244 VanDerWaalsContact CE-OE1 3.27Å; K155-L246 HydrophobicContact CB-CD2 4.22Å; K155-L246 HydrophobicContact CD-CD2 3.98Å; K155-L246 HydrophobicContact CG-CD2 3.79Å; K155-D247 IonicContact NZ-OD1 3.75Å; K155-D247 PolarHBondContact NZ-OD1 2.83Å; K155-D247 IonicContact NZ-OD2 2.87Å; K155-D247 PolarHBondContact NZ-OD2 3.3Å
156R90.3Very high78Confident9 Ų965.5 Ų65.53%0.03431%0.312CS..EExtended strand (participates in β ladder)trans-132160.7177.8-59-172.2-179.5154.5-3.1110.1E82 V110 D151 W160E82-R156 IonicContact OE1-CZ 3.83Å; E82-R156 IonicContact OE1-NH1 2.68Å; E82-R156 PolarHBondContact OE1-NH1 3.36Å; E82-R156 IonicContact OE1-NH2 3.19Å; E82-R156 PolarHBondContact OE1-NH2 2.68Å; E82-R156 IonicContact OE2-CZ 2.72Å; E82-R156 IonicContact OE2-NH1 2.66Å; E82-R156 IonicContact OE2-NH2 3.05Å; E82-R156 PolarHBondContact OE2-NH2 2.86Å; V110-R156 HydrophobicContact CB-CB 4.33Å; V110-R156 PolarHBondContact N-O 2.68Å; V110-R156 PolarHBondContact O-N 2.85Å; D151-R156 PolarHBondContact O-NH2 3.18Å; R156-W160 HydrophobicContact CB-CD2 4.29Å; R156-W160 HydrophobicContact CB-CE3 3.91Å; R156-W160 VanDerWaalsContact CD-CZ3 3.4Å; R156-W160 HydrophobicContact CG-CD2 4.46Å; R156-W160 HydrophobicContact CG-CE3 4.21Å
157S93.8Very high79.5Confident23 Ų2362.4 Ų62.416%0.16131%0.312CS..EExtended strand (participates in β ladder)trans-74.7157.8171.5580000110.7S159 W160 F161S157-S159 VanDerWaalsContact C-N 3.27Å; S157-W160 PolarHBondContact O-N 3.44Å; S157-W160 WeakPolarHBondContact OG-CB 3.22Å; S157-W160 PolarHBondContact OG-N 2.77Å; S157-F161 PolarHBondContact O-N 2.89Å; S157-F161 VanDerWaalsContact O-N 3.16Å
158I95.6Very high81.4Confident0 Ų058.6 Ų58.60%030%0.299CS..Hα-helixtrans-67.1-35.9169.2-70.5-179000109.8L88 I90 D107 G108 V110 W160 F161 I162 W176L88-I158 HydrophobicContact CD2-CG1 4.42Å; I90-I158 HydrophobicContact CD1-CD1 4.33Å; I90-I158 HydrophobicContact CG1-CD1 3.76Å; D107-I158 WeakPolarHBondContact OD1-CA 3.28Å; D107-I158 PolarHBondContact OD1-N 3.27Å; G108-I158 PolarHBondContact O-N 2.9Å; V110-I158 HydrophobicContact CG2-CG1 4.05Å; I158-W160 VanDerWaalsContact C-N 3.29Å; I158-W160 PolarHBondContact O-N 2.94Å; I158-F161 CarbonylContact O-C 3.54Å; I158-F161 WeakPolarHBondContact O-CA 3.41Å; I158-F161 WeakPolarHBondContact O-CB 3.37Å; I158-F161 PolarHBondContact O-N 3.1Å; I158-I162 HydrophobicContact CG2-CD1 4.37Å; I158-I162 HydrophobicContact CG2-CG1 4.09Å; I158-I162 WeakPolarHBondContact O-CG1 3.45Å; I158-I162 PolarHBondContact O-N 2.89Å; I158-W176 HydrophobicContact CG2-CH2 3.76Å; I158-W176 HydrophobicContact CG2-CZ2 3.76Å
159S94.3Very high83.5Confident56 Ų5658.9 Ų58.939%0.39231%0.305SS..Hα-helixtrans-52-45.9173-650000112.5D107 S157 I162 E163D107-S159 PolarHBondContact OD1-N 3.21Å; D107-S159 PolarHBondContact OD1-OG 2.94Å; D107-S159 PolarHBondContact OD2-OG 2.89Å; S157-S159 VanDerWaalsContact C-N 3.27Å; S159-I162 PolarHBondContact O-N 3.47Å; S159-E163 PolarHBondContact O-N 3.18Å
160W93.8Very high85.5Confident39 Ų3957.7 Ų57.715%0.14829%0.294CS..Hα-helixtrans-64.6-42174.4178.397.3000111.5M81 V150 D151 R156 S157 I158 I162 E163 F164M81-W160 HydrophobicContact CE-CZ3 4.09Å; M81-W160 HydrophobicContact SD-CE3 4.49Å; M81-W160 HydrophobicContact SD-CH2 3.88Å; M81-W160 HydrophobicContact SD-CZ3 3.38Å; M81-W160 WeakPolarHBondContact SD-CZ3 3.46Å; V150-W160 PolarHBondContact O-NE1 2.92Å; D151-W160 PolarHBondContact OD1-NE1 2.66Å; R156-W160 HydrophobicContact CB-CD2 4.29Å; R156-W160 HydrophobicContact CB-CE3 3.91Å; R156-W160 VanDerWaalsContact CD-CZ3 3.4Å; R156-W160 HydrophobicContact CG-CD2 4.46Å; R156-W160 HydrophobicContact CG-CE3 4.21Å; S157-W160 PolarHBondContact O-N 3.44Å; S157-W160 WeakPolarHBondContact OG-CB 3.22Å; S157-W160 PolarHBondContact OG-N 2.77Å; I158-W160 VanDerWaalsContact C-N 3.29Å; I158-W160 PolarHBondContact O-N 2.94Å; W160-I162 VanDerWaalsContact C-N 3.31Å; W160-I162 PolarHBondContact O-N 2.93Å; W160-E163 WeakPolarHBondContact O-CB 3.35Å; W160-E163 PolarHBondContact O-N 3.19Å; W160-E163 VanDerWaalsContact O-N 3.11Å; W160-F164 HydrophobicContact CE3-CB 4.34Å; W160-F164 HydrophobicContact CH2-CB 3.76Å; W160-F164 AromaticContact CH2-CD2 3.73Å; W160-F164 HydrophobicContact CH2-CD2 3.73Å; W160-F164 AromaticContact CH2-CG 3.93Å; W160-F164 HydrophobicContact CH2-CG 3.93Å; W160-F164 HydrophobicContact CZ2-CB 4.49Å; W160-F164 HydrophobicContact CZ3-CB 3.71Å; W160-F164 HydrophobicContact CZ3-CD2 4.33Å; W160-F164 HydrophobicContact CZ3-CG 4.08Å; W160-F164 PolarHBondContact O-N 2.88Å
161F94.9Very high87.6Confident0 Ų057 Ų570%029%0.286CS..Hα-helixtrans-65-34.5179.4171.8-109.1000112.8F79 M81 F86 L88 V110 S157 I158 E163 F164 L165 F175 L223F79-F161 HydrophobicContact CE1-CE2 4.23Å; M81-F161 HydrophobicContact SD-CD2 4.09Å; F86-F161 HydrophobicContact CE1-CE2 4.34Å; F86-F161 HydrophobicContact CE2-CD2 4.49Å; F86-F161 AromaticContact CE2-CE2 3.94Å; F86-F161 HydrophobicContact CE2-CE2 3.94Å; F86-F161 HydrophobicContact CE2-CZ 4.02Å; F86-F161 HydrophobicContact CZ-CD2 4.32Å; F86-F161 AromaticContact CZ-CE2 3.49Å; F86-F161 HydrophobicContact CZ-CE2 3.49Å; F86-F161 VanDerWaalsContact CZ-CE2 3.49Å; F86-F161 AromaticContact CZ-CZ 3.75Å; F86-F161 HydrophobicContact CZ-CZ 3.75Å; L88-F161 HydrophobicContact CD1-CE1 4.35Å; L88-F161 HydrophobicContact CD2-CD1 4.21Å; L88-F161 HydrophobicContact CD2-CE1 4.35Å; V110-F161 HydrophobicContact CG2-CB 3.76Å; V110-F161 HydrophobicContact CG2-CG 4.23Å; S157-F161 PolarHBondContact O-N 2.89Å; S157-F161 VanDerWaalsContact O-N 3.16Å; I158-F161 CarbonylContact O-C 3.54Å; I158-F161 WeakPolarHBondContact O-CA 3.41Å; I158-F161 WeakPolarHBondContact O-CB 3.37Å; I158-F161 PolarHBondContact O-N 3.1Å; F161-E163 VanDerWaalsContact C-N 3.32Å; F161-F164 HydrophobicContact CD2-CD1 4.15Å; F161-F164 HydrophobicContact CE2-CD1 4.17Å; F161-F164 WeakPolarHBondContact O-CB 3.46Å; F161-F164 PolarHBondContact O-N 2.89Å; F161-L165 HydrophobicContact CD1-CD1 4.2Å; F161-L165 HydrophobicContact CD1-CG 4.47Å; F161-L165 HydrophobicContact CE1-CD1 3.54Å; F161-L165 HydrophobicContact CE1-CD2 4.46Å; F161-L165 HydrophobicContact CE1-CG 3.98Å; F161-L165 HydrophobicContact CE2-CD1 4.47Å; F161-L165 HydrophobicContact CE2-CD2 4Å; F161-L165 HydrophobicContact CE2-CG 4.04Å; F161-L165 HydrophobicContact CZ-CD1 3.69Å; F161-L165 HydrophobicContact CZ-CD2 3.75Å; F161-L165 HydrophobicContact CZ-CG 3.73Å; F161-L165 WeakPolarHBondContact O-CG 3.16Å; F161-L165 PolarHBondContact O-N 3.34Å; F161-F175 HydrophobicContact CE1-CE2 4.07Å; F161-F175 HydrophobicContact CE1-CZ 4.19Å; F161-L223 HydrophobicContact CE1-CD1 3.91Å; F161-L223 HydrophobicContact CZ-CD1 3.62Å
162I94.9Very high89.6Confident9 Ų953 Ų535%0.04627%0.266CS..Hα-helixtrans-61.5-43.7172.1-67.8-46.9000110.6I158 S159 W160 F164 L165 R166 V172 F175 W176I158-I162 HydrophobicContact CG2-CD1 4.37Å; I158-I162 HydrophobicContact CG2-CG1 4.09Å; I158-I162 WeakPolarHBondContact O-CG1 3.45Å; I158-I162 PolarHBondContact O-N 2.89Å; S159-I162 PolarHBondContact O-N 3.47Å; W160-I162 VanDerWaalsContact C-N 3.31Å; W160-I162 PolarHBondContact O-N 2.93Å; I162-F164 VanDerWaalsContact C-N 3.34Å; I162-L165 HydrophobicContact CD1-CD1 4.36Å; I162-L165 WeakPolarHBondContact O-CB 3.5Å; I162-L165 PolarHBondContact O-N 2.93Å; I162-R166 WeakPolarHBondContact O-CG 3.28Å; I162-R166 PolarHBondContact O-N 3.26Å; I162-V172 HydrophobicContact CD1-CG1 4.18Å; I162-V172 HydrophobicContact CG2-CB 4.36Å; I162-V172 HydrophobicContact CG2-CG1 3.5Å; I162-V172 HydrophobicContact CG2-CG2 3.89Å; I162-F175 HydrophobicContact CD1-CD1 3.59Å; I162-F175 HydrophobicContact CD1-CE1 3.54Å; I162-F175 HydrophobicContact CD1-CZ 4.48Å; I162-W176 HydrophobicContact CD1-CZ2 4.19Å; I162-W176 HydrophobicContact CG1-CZ2 4.14Å
163E94.4Very high91.5Very high93 Ų9348 Ų4844%0.43526%0.259SS..Hα-helixtrans-64.3-41.2176.4-167.655.8-151.300111.7S159 W160 F161 L165 R166 V167S159-E163 PolarHBondContact O-N 3.18Å; W160-E163 WeakPolarHBondContact O-CB 3.35Å; W160-E163 PolarHBondContact O-N 3.19Å; W160-E163 VanDerWaalsContact O-N 3.11Å; F161-E163 VanDerWaalsContact C-N 3.32Å; E163-L165 VanDerWaalsContact C-N 3.31Å; E163-L165 PolarHBondContact O-N 2.89Å; E163-R166 WeakPolarHBondContact O-CB 3.49Å; E163-R166 PolarHBondContact O-N 3.03Å; E163-R166 VanDerWaalsContact O-N 3.13Å; E163-R166 IonicContact OE2-CZ 3.1Å; E163-R166 IonicContact OE2-NH1 2.68Å; E163-R166 PolarHBondContact OE2-NH1 3.46Å; E163-V167 WeakPolarHBondContact O-CG2 3.45Å; E163-V167 PolarHBondContact O-N 3.34Å
164F93.6Very high93Very high37 Ų3752.3 Ų52.316%0.16228%0.275CS..Hα-helixtrans-55.7-44.2171.1173-90.9000112.1F79 M81 W160 F161 I162 V167 N168F79-F164 HydrophobicContact CE1-CE1 4.01Å; F79-F164 HydrophobicContact CZ-CE1 4.3Å; M81-F164 HydrophobicContact CG-CE1 4.32Å; M81-F164 HydrophobicContact CG-CE2 4.29Å; M81-F164 HydrophobicContact CG-CZ 4.1Å; W160-F164 HydrophobicContact CE3-CB 4.34Å; W160-F164 HydrophobicContact CH2-CB 3.76Å; W160-F164 AromaticContact CH2-CD2 3.73Å; W160-F164 HydrophobicContact CH2-CD2 3.73Å; W160-F164 AromaticContact CH2-CG 3.93Å; W160-F164 HydrophobicContact CH2-CG 3.93Å; W160-F164 HydrophobicContact CZ2-CB 4.49Å; W160-F164 HydrophobicContact CZ3-CB 3.71Å; W160-F164 HydrophobicContact CZ3-CD2 4.33Å; W160-F164 HydrophobicContact CZ3-CG 4.08Å; W160-F164 PolarHBondContact O-N 2.88Å; F161-F164 HydrophobicContact CD2-CD1 4.15Å; F161-F164 HydrophobicContact CE2-CD1 4.17Å; F161-F164 WeakPolarHBondContact O-CB 3.46Å; F161-F164 PolarHBondContact O-N 2.89Å; I162-F164 VanDerWaalsContact C-N 3.34Å; F164-V167 PolarHBondContact O-N 2.87Å; F164-N168 VanDerWaalsContact CE2-ND2 3.34Å; F164-N168 WeakPolarHBondContact CE2-ND2 3.39Å; F164-N168 WeakPolarHBondContact CZ-ND2 3.42Å; F164-N168 WeakPolarHBondContact O-CB 3.45Å; F164-N168 PolarHBondContact O-N 3.08Å; F164-N168 VanDerWaalsContact O-N 3.1Å; F164-N168 PolarHBondContact O-ND2 2.97Å
165L94.7Very high94Very high0 Ų052 Ų520%027%0.272CS..Hα-helixtrans-62.9-41.6175.9-72.7-177.8000112.1F79 F161 I162 E163 N168 N169 C170 V172 F175 L227F79-L165 HydrophobicContact CE1-CD2 4.11Å; F79-L165 HydrophobicContact CZ-CD2 4.11Å; F161-L165 HydrophobicContact CD1-CD1 4.2Å; F161-L165 HydrophobicContact CD1-CG 4.47Å; F161-L165 HydrophobicContact CE1-CD1 3.54Å; F161-L165 HydrophobicContact CE1-CD2 4.46Å; F161-L165 HydrophobicContact CE1-CG 3.98Å; F161-L165 HydrophobicContact CE2-CD1 4.47Å; F161-L165 HydrophobicContact CE2-CD2 4Å; F161-L165 HydrophobicContact CE2-CG 4.04Å; F161-L165 HydrophobicContact CZ-CD1 3.69Å; F161-L165 HydrophobicContact CZ-CD2 3.75Å; F161-L165 HydrophobicContact CZ-CG 3.73Å; F161-L165 WeakPolarHBondContact O-CG 3.16Å; F161-L165 PolarHBondContact O-N 3.34Å; I162-L165 HydrophobicContact CD1-CD1 4.36Å; I162-L165 WeakPolarHBondContact O-CB 3.5Å; I162-L165 PolarHBondContact O-N 2.93Å; E163-L165 VanDerWaalsContact C-N 3.31Å; E163-L165 PolarHBondContact O-N 2.89Å; L165-N168 CarbonylContact O-C 3.43Å; L165-N168 PolarHBondContact O-N 3.19Å; L165-N169 PolarHBondContact O-N 2.65Å; L165-C170 HydrophobicContact CB-CB 3.95Å; L165-C170 HydrophobicContact CD2-CB 3.85Å; L165-C170 HydrophobicContact CG-CB 4.42Å; L165-C170 WeakPolarHBondContact O-CB 3.44Å; L165-C170 PolarHBondContact O-N 3.46Å; L165-V172 HydrophobicContact CB-CG2 3.99Å; L165-F175 HydrophobicContact CD1-CB 4.49Å; L165-F175 HydrophobicContact CD1-CD2 4.43Å; L165-F175 HydrophobicContact CD1-CG 4.27Å; L165-L227 HydrophobicContact CD2-CD1 4.22Å; L165-L227 HydrophobicContact CD2-CD2 3.99Å
166R94.6Very high94.5Very high133 Ų13352.1 Ų52.150%0.50227%0.272SS..Hα-helixtrans-61.3-48.3177.3-67.9-175.7-171.6126-1.1111.8I162 E163 N168 N169 V172I162-R166 WeakPolarHBondContact O-CG 3.28Å; I162-R166 PolarHBondContact O-N 3.26Å; E163-R166 WeakPolarHBondContact O-CB 3.49Å; E163-R166 PolarHBondContact O-N 3.03Å; E163-R166 VanDerWaalsContact O-N 3.13Å; E163-R166 IonicContact OE2-CZ 3.1Å; E163-R166 IonicContact OE2-NH1 2.68Å; E163-R166 PolarHBondContact OE2-NH1 3.46Å; R166-N168 PolarHBondContact O-N 3.02Å; R166-N169 PolarHBondContact O-N 3.16Å; R166-V172 HydrophobicContact CG-CG2 3.66Å
167V94.6Very high94.8Very high105 Ų10557.1 Ų57.164%0.63630%0.296SS*.Hα-helixtrans-60.7-32.4178.3172.70000111.4E163 F164 N169E163-V167 WeakPolarHBondContact O-CG2 3.45Å; E163-V167 PolarHBondContact O-N 3.34Å; F164-V167 PolarHBondContact O-N 2.87Å; V167-N169 VanDerWaalsContact C-N 3.31Å; V167-N169 PolarHBondContact O-N 2.94Å
168N92Very high95Very high83 Ų8358 Ų5844%0.44430%0.299SS..THydrogen-bonded Turntrans-89.918.5176.6-71-86000113.7F164 L165 R166 C170F164-N168 VanDerWaalsContact CE2-ND2 3.34Å; F164-N168 WeakPolarHBondContact CE2-ND2 3.39Å; F164-N168 WeakPolarHBondContact CZ-ND2 3.42Å; F164-N168 WeakPolarHBondContact O-CB 3.45Å; F164-N168 PolarHBondContact O-N 3.08Å; F164-N168 VanDerWaalsContact O-N 3.1Å; F164-N168 PolarHBondContact O-ND2 2.97Å; L165-N168 CarbonylContact O-C 3.43Å; L165-N168 PolarHBondContact O-N 3.19Å; R166-N168 PolarHBondContact O-N 3.02Å; N168-C170 PolarHBondContact O-N 3.38Å; N168-C170 PolarHBondContact O-SG 2.86Å
169N93.6Very high95.1Very high157 Ų15758 Ų5884%0.8430%0.299SS*.THydrogen-bonded Turntrans54.134.6178.7-64-53.3000114.5L165 R166 V167L165-N169 PolarHBondContact O-N 2.65Å; R166-N169 PolarHBondContact O-N 3.16Å; V167-N169 VanDerWaalsContact C-N 3.31Å; V167-N169 PolarHBondContact O-N 2.94Å
170C93.4Very high95.3Very high32 Ų3256 Ų5622%0.21628%0.284CS..  trans-94146.2175.5-63.10000111L165 N168 V172 L227L165-C170 HydrophobicContact CB-CB 3.95Å; L165-C170 HydrophobicContact CD2-CB 3.85Å; L165-C170 HydrophobicContact CG-CB 4.42Å; L165-C170 WeakPolarHBondContact O-CB 3.44Å; L165-C170 PolarHBondContact O-N 3.46Å; N168-C170 PolarHBondContact O-N 3.38Å; N168-C170 PolarHBondContact O-SG 2.86Å; C170-V172 PolarHBondContact O-N 3.12Å; C170-V172 VanDerWaalsContact O-N 3.14Å; C170-L227 HydrophobicContact CB-CD1 3.72Å
171D94.9Very high95.5Very high94 Ų9456.7 Ų56.750%0.50329%0.29SS..  trans-77.4101.3-179.9-171.8-16.7000111.6S173 K174 F175D171-S173 WeakPolarHBondContact OD1-CB 3.41Å; D171-S173 PolarHBondContact OD1-N 2.83Å; D171-K174 HydrophobicContact CB-CB 3.88Å; D171-K174 PolarHBondContact OD1-N 2.92Å; D171-K174 WeakPolarHBondContact OD2-CB 3.36Å; D171-F175 PolarHBondContact O-N 2.97Å; D171-F175 VanDerWaalsContact O-N 3.1Å
172V95.5Very high95.7Very high19 Ų1956.9 Ų56.912%0.11529%0.29CS..Hα-helixtrans-69.3-34.6178.5168.70000112.5I162 L165 R166 C170 F175 W176I162-V172 HydrophobicContact CD1-CG1 4.18Å; I162-V172 HydrophobicContact CG2-CB 4.36Å; I162-V172 HydrophobicContact CG2-CG1 3.5Å; I162-V172 HydrophobicContact CG2-CG2 3.89Å; L165-V172 HydrophobicContact CB-CG2 3.99Å; R166-V172 HydrophobicContact CG-CG2 3.66Å; C170-V172 PolarHBondContact O-N 3.12Å; C170-V172 VanDerWaalsContact O-N 3.14Å; V172-F175 WeakPolarHBondContact O-CB 3.42Å; V172-F175 PolarHBondContact O-N 3.17Å; V172-W176 PolarHBondContact O-N 2.77Å; V172-W176 VanDerWaalsContact O-N 3.11Å
173S95.7Very high95.9Very high77 Ų7756.4 Ų56.454%0.53829%0.288SS..Hα-helixtrans-65.3-48.6179.3-62.60000109.3D171 F175 W176 E177D171-S173 WeakPolarHBondContact OD1-CB 3.41Å; D171-S173 PolarHBondContact OD1-N 2.83Å; S173-F175 VanDerWaalsContact C-N 3.32Å; S173-F175 PolarHBondContact O-N 3.33Å; S173-W176 PolarHBondContact O-N 2.96Å; S173-W176 VanDerWaalsContact O-N 3.16Å; S173-E177 WeakPolarHBondContact O-CG 3.46Å; S173-E177 PolarHBondContact O-N 3.29Å
174K96.4Very high96Very high97 Ų9752 Ų5242%0.42227%0.267SS..Hα-helixtrans-58.7-41.2174.3179.5163179.344.10112.9D171 W176 E177 D178D171-K174 HydrophobicContact CB-CB 3.88Å; D171-K174 PolarHBondContact OD1-N 2.92Å; D171-K174 WeakPolarHBondContact OD2-CB 3.36Å; K174-W176 PolarHBondContact O-N 2.97Å; K174-E177 PolarHBondContact O-N 3.14Å; K174-D178 WeakPolarHBondContact CE-OD2 3.37Å; K174-D178 VanDerWaalsContact NZ-CG 3.31Å; K174-D178 IonicContact NZ-OD1 3.67Å; K174-D178 PolarHBondContact NZ-OD1 2.78Å; K174-D178 IonicContact NZ-OD2 3.7Å; K174-D178 PolarHBondContact NZ-OD2 2.88Å; K174-D178 WeakPolarHBondContact O-CB 3.36Å; K174-D178 VanDerWaalsContact O-CG 3.3Å; K174-D178 PolarHBondContact O-N 3.3Å
175F96.5Very high96.3Very high5 Ų550.8 Ų50.82%0.02226%0.262CS..Hα-helixtrans-55.9-49.8174.9164.1-95.8000111.4L88 F161 I162 L165 D171 V172 S173 D178 I179 L223L88-F175 HydrophobicContact CD1-CE2 3.7Å; L88-F175 HydrophobicContact CD1-CZ 3.75Å; F161-F175 HydrophobicContact CE1-CE2 4.07Å; F161-F175 HydrophobicContact CE1-CZ 4.19Å; I162-F175 HydrophobicContact CD1-CD1 3.59Å; I162-F175 HydrophobicContact CD1-CE1 3.54Å; I162-F175 HydrophobicContact CD1-CZ 4.48Å; L165-F175 HydrophobicContact CD1-CB 4.49Å; L165-F175 HydrophobicContact CD1-CD2 4.43Å; L165-F175 HydrophobicContact CD1-CG 4.27Å; D171-F175 PolarHBondContact O-N 2.97Å; D171-F175 VanDerWaalsContact O-N 3.1Å; V172-F175 WeakPolarHBondContact O-CB 3.42Å; V172-F175 PolarHBondContact O-N 3.17Å; S173-F175 VanDerWaalsContact C-N 3.32Å; S173-F175 PolarHBondContact O-N 3.33Å; F175-D178 PolarHBondContact O-N 2.88Å; F175-I179 HydrophobicContact CD2-CG1 4.2Å; F175-I179 HydrophobicContact CE1-CG1 4.3Å; F175-I179 HydrophobicContact CE2-CD1 4.12Å; F175-I179 HydrophobicContact CE2-CG1 3.82Å; F175-I179 HydrophobicContact CZ-CD1 4.35Å; F175-I179 HydrophobicContact CZ-CG1 3.88Å; F175-I179 WeakPolarHBondContact O-CB 3.29Å; F175-I179 WeakPolarHBondContact O-CG1 3.36Å; F175-I179 PolarHBondContact O-N 3.31Å; F175-L223 HydrophobicContact CD2-CD1 4.23Å; F175-L223 HydrophobicContact CD2-CD2 4.42Å; F175-L223 HydrophobicContact CE2-CD1 3.91Å; F175-L223 HydrophobicContact CE2-CD2 4.07Å
176W97Very high96.5Very high26 Ų2651.5 Ų51.510%0.09827%0.267CS..Hα-helixtrans-69.4-33.1-179.7-79119.9000113.4L104 I158 I162 V172 S173 K174 I179 S180L104-W176 HydrophobicContact CD1-CE3 4.22Å; L104-W176 HydrophobicContact CD1-CZ3 4.11Å; L104-W176 HydrophobicContact CD2-CE3 3.8Å; L104-W176 HydrophobicContact CD2-CH2 4.17Å; L104-W176 HydrophobicContact CD2-CZ3 3.43Å; L104-W176 VanDerWaalsContact CD2-CZ3 3.43Å; L104-W176 HydrophobicContact CG-CZ3 4.28Å; I158-W176 HydrophobicContact CG2-CH2 3.76Å; I158-W176 HydrophobicContact CG2-CZ2 3.76Å; I162-W176 HydrophobicContact CD1-CZ2 4.19Å; I162-W176 HydrophobicContact CG1-CZ2 4.14Å; V172-W176 PolarHBondContact O-N 2.77Å; V172-W176 VanDerWaalsContact O-N 3.11Å; S173-W176 PolarHBondContact O-N 2.96Å; S173-W176 VanDerWaalsContact O-N 3.16Å; K174-W176 PolarHBondContact O-N 2.97Å; W176-I179 HydrophobicContact CE3-CG2 4.46Å; W176-S180 VanDerWaalsContact O-CB 3.28Å; W176-S180 WeakPolarHBondContact O-CB 3.39Å; W176-S180 PolarHBondContact O-N 3.38Å; W176-S180 PolarHBondContact O-OG 3.15Å
177E96.9Very high96.6Very high115 Ų11546 Ų4654%0.53725%0.247SC..Hα-helixtrans-62.6-52.6172.4-74168.8-168.800111.1S173 K174 I179 S180 E181S173-E177 WeakPolarHBondContact O-CG 3.46Å; S173-E177 PolarHBondContact O-N 3.29Å; K174-E177 PolarHBondContact O-N 3.14Å; E177-I179 VanDerWaalsContact C-N 3.3Å; E177-I179 PolarHBondContact O-N 2.92Å; E177-S180 PolarHBondContact O-N 2.82Å; E177-S180 VanDerWaalsContact O-N 3.11Å; E177-E181 PolarHBondContact O-N 2.82Å
178D97.7Very high96.8Very high42 Ų4241 Ų4123%0.22522%0.217CC..Hα-helixtrans-61.7-38.7-178.9-70.6-24.4000111.2K174 F175 L182 P229K174-D178 WeakPolarHBondContact CE-OD2 3.37Å; K174-D178 VanDerWaalsContact NZ-CG 3.31Å; K174-D178 IonicContact NZ-OD1 3.67Å; K174-D178 PolarHBondContact NZ-OD1 2.78Å; K174-D178 IonicContact NZ-OD2 3.7Å; K174-D178 PolarHBondContact NZ-OD2 2.88Å; K174-D178 WeakPolarHBondContact O-CB 3.36Å; K174-D178 VanDerWaalsContact O-CG 3.3Å; K174-D178 PolarHBondContact O-N 3.3Å; F175-D178 PolarHBondContact O-N 2.88Å; D178-L182 VanDerWaalsContact O-CB 3.32Å; D178-L182 WeakPolarHBondContact O-CB 3.49Å; D178-L182 PolarHBondContact O-N 2.89Å; D178-P229 HydrophobicContact CB-CG 3.72Å
179I98.2Very high97.1Very high0 Ų039.6 Ų39.60%021%0.211CC..Hα-helixtrans-65.8-45.5173.7-68.3-70000111.5I90 L104 F175 W176 E177 L182 V183 I221 P229I90-I179 HydrophobicContact CD1-CD1 3.85Å; I90-I179 HydrophobicContact CD1-CG1 4.22Å; I90-I179 HydrophobicContact CD1-CG2 3.49Å; I90-I179 VanDerWaalsContact CD1-CG2 3.49Å; L104-I179 HydrophobicContact CD1-CG2 3.66Å; F175-I179 HydrophobicContact CD2-CG1 4.2Å; F175-I179 HydrophobicContact CE1-CG1 4.3Å; F175-I179 HydrophobicContact CE2-CD1 4.12Å; F175-I179 HydrophobicContact CE2-CG1 3.82Å; F175-I179 HydrophobicContact CZ-CD1 4.35Å; F175-I179 HydrophobicContact CZ-CG1 3.88Å; F175-I179 WeakPolarHBondContact O-CB 3.29Å; F175-I179 WeakPolarHBondContact O-CG1 3.36Å; F175-I179 PolarHBondContact O-N 3.31Å; W176-I179 HydrophobicContact CE3-CG2 4.46Å; E177-I179 VanDerWaalsContact C-N 3.3Å; E177-I179 PolarHBondContact O-N 2.92Å; I179-L182 WeakPolarHBondContact O-CB 3.31Å; I179-L182 PolarHBondContact O-N 2.76Å; I179-V183 HydrophobicContact CG2-CG2 4.48Å; I179-V183 VanDerWaalsContact O-CG2 3.31Å; I179-V183 WeakPolarHBondContact O-CG2 3.38Å; I179-V183 PolarHBondContact O-N 3.22Å; I179-I221 HydrophobicContact CD1-CD1 3.68Å; I179-I221 HydrophobicContact CD1-CG2 3.81Å; I179-I221 HydrophobicContact CG2-CD1 4.44Å; I179-P229 HydrophobicContact CD1-CB 3.54Å; I179-P229 HydrophobicContact CD1-CG 4.17Å; I179-P229 HydrophobicContact CG1-CB 4.43Å
180S98.2Very high97.2Very high12 Ų1233.9 Ų33.98%0.08419%0.185CC..Hα-helixtrans-63.3-44.9-179.1-58.70000110.7W176 E177 L182 V183 V184 R339W176-S180 VanDerWaalsContact O-CB 3.28Å; W176-S180 WeakPolarHBondContact O-CB 3.39Å; W176-S180 PolarHBondContact O-N 3.38Å; W176-S180 PolarHBondContact O-OG 3.15Å; E177-S180 PolarHBondContact O-N 2.82Å; E177-S180 VanDerWaalsContact O-N 3.11Å; S180-L182 PolarHBondContact O-N 2.78Å; S180-V183 PolarHBondContact O-N 2.83Å; S180-V184 WeakPolarHBondContact O-CG2 3.31Å; S180-V184 PolarHBondContact O-N 2.83Å; S180-R339 PolarHBondContact OG-NH2 2.95Å
181E97.8Very high97.4Very high55 Ų5533 Ų3326%0.25718%0.178SC..Hα-helixtrans-60-44.3174.9-77.6-158-155.700112.4E177 V183 K185E177-E181 PolarHBondContact O-N 2.82Å; E181-V183 VanDerWaalsContact C-N 3.34Å; E181-V183 PolarHBondContact O-N 2.52Å; E181-K185 VanDerWaalsContact O-CB 3.3Å; E181-K185 WeakPolarHBondContact O-CB 3.39Å; E181-K185 WeakPolarHBondContact O-CG 3.19Å; E181-K185 PolarHBondContact O-N 3.37Å; E181-K185 VanDerWaalsContact OE2-CE 3.27Å; E181-K185 WeakPolarHBondContact OE2-CE 3.4Å; E181-K185 IonicContact OE2-NZ 2.88Å; E181-K185 PolarHBondContact OE2-NZ 2.85Å
182L98.4Very high97.4Very high3 Ų328.6 Ų28.62%0.01616%0.155CC..Hα-helixtrans-57.4-48.5176.8179160.7000110.8F11 D178 I179 S180 T186 F219 I221 P229 L231F11-L182 HydrophobicContact CB-CD1 4.01Å; F11-L182 HydrophobicContact CB-CG 4.34Å; F11-L182 HydrophobicContact CD2-CD1 4.04Å; F11-L182 HydrophobicContact CD2-CG 3.65Å; F11-L182 HydrophobicContact CE2-CG 4.08Å; F11-L182 HydrophobicContact CG-CD1 4.2Å; F11-L182 HydrophobicContact CG-CG 3.99Å; D178-L182 VanDerWaalsContact O-CB 3.32Å; D178-L182 WeakPolarHBondContact O-CB 3.49Å; D178-L182 PolarHBondContact O-N 2.89Å; I179-L182 WeakPolarHBondContact O-CB 3.31Å; I179-L182 PolarHBondContact O-N 2.76Å; S180-L182 PolarHBondContact O-N 2.78Å; L182-T186 VanDerWaalsContact O-CB 3.26Å; L182-T186 WeakPolarHBondContact O-CB 3.29Å; L182-T186 PolarHBondContact O-N 3.2Å; L182-T186 PolarHBondContact O-OG1 3.37Å; L182-F219 HydrophobicContact CD2-CD1 4.35Å; L182-I221 HydrophobicContact CD1-CD1 4.44Å; L182-I221 HydrophobicContact CD2-CD1 3.98Å; L182-I221 HydrophobicContact CD2-CG1 4.45Å; L182-P229 HydrophobicContact CD1-CB 3.85Å; L182-P229 HydrophobicContact CD1-CG 4.12Å; L182-L231 HydrophobicContact CD1-CB 4.29Å; L182-L231 HydrophobicContact CD2-CB 4.13Å; L182-L231 HydrophobicContact CD2-CD1 4.19Å; L182-L231 HydrophobicContact CG-CB 4.47Å
183V98.6Very high97.4Very high0 Ų032.8 Ų32.80%017%0.173CC..Hα-helixtrans-63.8-50.5-178.6172.60000111.1I92 I102 I179 S180 E181 T186 L187 F219 I341I92-V183 HydrophobicContact CB-CG1 4.37Å; I92-V183 HydrophobicContact CD1-CB 4.36Å; I92-V183 HydrophobicContact CD1-CG1 3.77Å; I92-V183 HydrophobicContact CD1-CG2 3.76Å; I92-V183 HydrophobicContact CG1-CG1 3.73Å; I92-V183 HydrophobicContact CG1-CG2 4.06Å; I92-V183 HydrophobicContact CG2-CG1 3.75Å; I102-V183 HydrophobicContact CG2-CG1 4.12Å; I179-V183 HydrophobicContact CG2-CG2 4.48Å; I179-V183 VanDerWaalsContact O-CG2 3.31Å; I179-V183 WeakPolarHBondContact O-CG2 3.38Å; I179-V183 PolarHBondContact O-N 3.22Å; S180-V183 PolarHBondContact O-N 2.83Å; E181-V183 VanDerWaalsContact C-N 3.34Å; E181-V183 PolarHBondContact O-N 2.52Å; V183-T186 WeakPolarHBondContact O-CB 3.38Å; V183-T186 PolarHBondContact O-N 3.26Å; V183-L187 HydrophobicContact CG1-CD1 4.12Å; V183-L187 PolarHBondContact O-N 2.96Å; V183-F219 HydrophobicContact CB-CE1 4.46Å; V183-F219 HydrophobicContact CG1-CE1 4.34Å; V183-F219 HydrophobicContact CG1-CZ 4.16Å; V183-F219 HydrophobicContact CG2-CD1 4.06Å; V183-F219 HydrophobicContact CG2-CE1 4.17Å; V183-F219 HydrophobicContact CG2-CG 4.5Å; V183-I341 HydrophobicContact CB-CD1 3.8Å; V183-I341 HydrophobicContact CG1-CD1 3.57Å
184V98.6Very high97.4Very high0 Ų032.5 Ų32.50%017%0.168CC..Hα-helixtrans-61.2-50.1-178.1174.70000110.6I102 S180 T186 L187 I188 I341 Y342 Y353I102-V184 HydrophobicContact CD1-CG2 4.43Å; S180-V184 WeakPolarHBondContact O-CG2 3.31Å; S180-V184 PolarHBondContact O-N 2.83Å; V184-T186 PolarHBondContact O-N 2.98Å; V184-L187 PolarHBondContact O-N 3.11Å; V184-L187 VanDerWaalsContact O-N 3.14Å; V184-I188 HydrophobicContact CG1-CD1 3.81Å; V184-I188 HydrophobicContact CG1-CG1 4.25Å; V184-I188 VanDerWaalsContact O-CG1 3.29Å; V184-I188 WeakPolarHBondContact O-CG1 3.47Å; V184-I188 PolarHBondContact O-N 3.41Å; V184-I341 HydrophobicContact CG2-CB 4.09Å; V184-I341 HydrophobicContact CG2-CD1 3.64Å; V184-I341 HydrophobicContact CG2-CG1 3.75Å; V184-Y342 HydrophobicContact CG1-CD2 3.7Å; V184-Y342 HydrophobicContact CG1-CE2 4.5Å; V184-Y342 HydrophobicContact CG1-CG 4.26Å; V184-Y353 HydrophobicContact CB-CE1 4.23Å; V184-Y353 HydrophobicContact CB-CE2 4.15Å; V184-Y353 HydrophobicContact CG1-CD1 3.91Å; V184-Y353 HydrophobicContact CG1-CD2 3.73Å; V184-Y353 HydrophobicContact CG1-CE1 3.83Å; V184-Y353 HydrophobicContact CG1-CE2 3.61Å; V184-Y353 HydrophobicContact CG1-CG 3.87Å; V184-Y353 HydrophobicContact CG2-CE2 4.29Å
185K98.4Very high97.2Very high12 Ų1228.6 Ų28.65%0.05215%0.151CC..Hα-helixtrans-59.5-37.2178.3-68.5175.1-166.4176.90111.6E8 Y9 F11 E181 I188 V189 Y353 L356E8-K185 VanDerWaalsContact OE2-CE 3.28Å; E8-K185 WeakPolarHBondContact OE2-CE 3.31Å; E8-K185 IonicContact OE2-NZ 3.35Å; E8-K185 PolarHBondContact OE2-NZ 2.92Å; Y9-K185 HydrophobicContact CE1-CB 3.95Å; Y9-K185 WeakPolarHBondContact CE1-O 3.48Å; Y9-K185 PolarHBondContact OH-O 2.93Å; F11-K185 HydrophobicContact CE1-CB 3.89Å; F11-K185 HydrophobicContact CE1-CD 3.96Å; F11-K185 HydrophobicContact CZ-CB 3.88Å; E181-K185 VanDerWaalsContact O-CB 3.3Å; E181-K185 WeakPolarHBondContact O-CB 3.39Å; E181-K185 WeakPolarHBondContact O-CG 3.19Å; E181-K185 PolarHBondContact O-N 3.37Å; E181-K185 VanDerWaalsContact OE2-CE 3.27Å; E181-K185 WeakPolarHBondContact OE2-CE 3.4Å; E181-K185 IonicContact OE2-NZ 2.88Å; E181-K185 PolarHBondContact OE2-NZ 2.85Å; K185-I188 PolarHBondContact O-N 3.19Å; K185-V189 WeakPolarHBondContact O-CG2 3.45Å; K185-V189 PolarHBondContact O-N 3.1Å; K185-Y353 HydrophobicContact CG-CE1 4.24Å; K185-L356 HydrophobicContact CD-CD1 4.3Å; K185-L356 HydrophobicContact CG-CD1 3.95Å
186T98.4Very high97Very high15 Ų1531.4 Ų31.49%0.09216%0.164CC..Hα-helixtrans-63.5-46.8176.3-60.50000111.8F11 L182 V183 V184 V189 F219 L231 I234F11-T186 WeakPolarHBondContact CE2-OG1 3.49Å; L182-T186 VanDerWaalsContact O-CB 3.26Å; L182-T186 WeakPolarHBondContact O-CB 3.29Å; L182-T186 PolarHBondContact O-N 3.2Å; L182-T186 PolarHBondContact O-OG1 3.37Å; V183-T186 WeakPolarHBondContact O-CB 3.38Å; V183-T186 PolarHBondContact O-N 3.26Å; V184-T186 PolarHBondContact O-N 2.98Å; T186-V189 WeakPolarHBondContact O-CB 3.48Å; T186-V189 PolarHBondContact O-N 3.49Å; T186-F219 HydrophobicContact CG2-CE1 3.92Å; T186-F219 HydrophobicContact CG2-CZ 4.32Å; T186-L231 HydrophobicContact CG2-CD2 3.69Å; T186-I234 HydrophobicContact CG2-CD1 3.35Å; T186-I234 HydrophobicContact CG2-CG1 4.44Å
187L98.4Very high96.8Very high18 Ų1832.5 Ų32.59%0.09418%0.179CC..Hα-helixtrans-70.5-30178.9-73.6171.9000112.8I92 V94 I102 V183 V184 V189 A190 E191 L217 F219I92-L187 HydrophobicContact CG2-CD1 4.08Å; V94-L187 HydrophobicContact CG2-CD1 3.68Å; V94-L187 HydrophobicContact CG2-CD2 4.3Å; I102-L187 HydrophobicContact CB-CD1 4.32Å; I102-L187 HydrophobicContact CD1-CB 3.7Å; I102-L187 HydrophobicContact CD1-CD1 3.54Å; I102-L187 HydrophobicContact CD1-CG 4.26Å; I102-L187 HydrophobicContact CG1-CD1 3.78Å; I102-L187 HydrophobicContact CG2-CD1 3.55Å; V183-L187 HydrophobicContact CG1-CD1 4.12Å; V183-L187 PolarHBondContact O-N 2.96Å; V184-L187 PolarHBondContact O-N 3.11Å; V184-L187 VanDerWaalsContact O-N 3.14Å; L187-V189 PolarHBondContact O-N 3.18Å; L187-A190 CarbonylContact O-C 3.42Å; L187-A190 PolarHBondContact O-N 3.06Å; L187-E191 WeakPolarHBondContact O-CB 3.32Å; L187-E191 PolarHBondContact O-N 3.29Å; L187-L217 HydrophobicContact CD2-CD1 3.89Å; L187-F219 HydrophobicContact CG-CZ 4.36Å
188I98Very high96.6Very high0 Ų028.4 Ų28.40%016%0.159CC..Hα-helixtrans-57.5-36.3170-74.7174.6000111.9V184 K185 A190 P192 Y353 L356 L357 A360V184-I188 HydrophobicContact CG1-CD1 3.81Å; V184-I188 HydrophobicContact CG1-CG1 4.25Å; V184-I188 VanDerWaalsContact O-CG1 3.29Å; V184-I188 WeakPolarHBondContact O-CG1 3.47Å; V184-I188 PolarHBondContact O-N 3.41Å; K185-I188 PolarHBondContact O-N 3.19Å; I188-A190 VanDerWaalsContact C-N 3.32Å; I188-P192 WeakPolarHBondContact O-CD 3.16Å; I188-Y353 HydrophobicContact CD1-CD1 3.97Å; I188-Y353 HydrophobicContact CD1-CG 4.09Å; I188-L356 HydrophobicContact CD1-CB 4.26Å; I188-L356 HydrophobicContact CG2-CB 4.09Å; I188-L357 HydrophobicContact CB-CD2 4.15Å; I188-L357 HydrophobicContact CB-CG 4.41Å; I188-L357 HydrophobicContact CD1-CG 4.18Å; I188-L357 HydrophobicContact CG1-CD2 3.87Å; I188-L357 HydrophobicContact CG1-CG 3.84Å; I188-L357 HydrophobicContact CG2-CD2 3.91Å; I188-L357 HydrophobicContact CG2-CG 3.98Å; I188-A360 HydrophobicContact CG2-CB 4.06Å; I188-A360 WeakPolarHBondContact O-CB 3.43Å
189V97.6Very high96.2Very high52 Ų5232.4 Ų32.432%0.31517%0.171SC..Hα-helixtrans-65.9-38175.1-172.40000111.4M1 Y9 K185 T186 L187M1-V189 HydrophobicContact CB-CG2 4.28Å; M1-V189 HydrophobicContact CG-CB 4.31Å; M1-V189 HydrophobicContact CG-CG1 3.82Å; M1-V189 HydrophobicContact CG-CG2 3.74Å; Y9-V189 HydrophobicContact CD1-CG2 4.2Å; Y9-V189 HydrophobicContact CE1-CG2 3.34Å; K185-V189 WeakPolarHBondContact O-CG2 3.45Å; K185-V189 PolarHBondContact O-N 3.1Å; T186-V189 WeakPolarHBondContact O-CB 3.48Å; T186-V189 PolarHBondContact O-N 3.49Å; L187-V189 PolarHBondContact O-N 3.18Å
190A96.9Very high95.7Very high37 Ų3738.3 Ų38.331%0.30620%0.2SC..Hα-helixtrans-78.8-28.7-17900000112.8L187 I188 H193 V194L187-A190 CarbonylContact O-C 3.42Å; L187-A190 PolarHBondContact O-N 3.06Å; I188-A190 VanDerWaalsContact C-N 3.32Å; A190-H193 WeakPolarHBondContact O-CA 3.38Å; A190-H193 WeakPolarHBondContact O-CB 3.49Å; A190-H193 PolarHBondContact O-N 3.34Å; A190-V194 HydrophobicContact CB-CG2 4.39Å; A190-V194 WeakPolarHBondContact O-CG2 3.48Å; A190-V194 PolarHBondContact O-N 3Å
191E96.2Very high95.2Very high13 Ų1343 Ų436%0.06123%0.232CC..Hα-helixtrans-47.7-53.6-173.8-179.852.2-149.500114.7L100 L187 H193 V194 L195 L357 F361L100-E191 WeakPolarHBondContact CD1-OE2 3.36Å; L100-E191 HydrophobicContact CD2-CB 4.4Å; L100-E191 HydrophobicContact CD2-CG 4.2Å; L187-E191 WeakPolarHBondContact O-CB 3.32Å; L187-E191 PolarHBondContact O-N 3.29Å; E191-H193 PolarHBondContact O-N 3.29Å; E191-V194 PolarHBondContact O-N 3.47Å; E191-L195 VanDerWaalsContact O-CB 3.27Å; E191-L195 WeakPolarHBondContact O-CB 3.27Å; E191-L195 PolarHBondContact O-N 2.95Å; E191-L357 HydrophobicContact CB-CD2 3.85Å; E191-L357 HydrophobicContact CG-CD2 3.61Å; E191-F361 HydrophobicContact CG-CE2 4.15Å; E191-F361 HydrophobicContact CG-CZ 4.37Å
192P96Very high94.4Very high2 Ų242.6 Ų42.61%0.01323%0.228CC..Hα-helixtrans-62.2-29.8-179.924.3-35.1000113.5I188 H196 A360 F361 F364I188-P192 WeakPolarHBondContact O-CD 3.16Å; P192-H196 VanDerWaalsContact O-CB 3.25Å; P192-H196 WeakPolarHBondContact O-CB 3.32Å; P192-H196 PolarHBondContact O-N 3.29Å; P192-A360 HydrophobicContact CG-CB 4.26Å; P192-F361 HydrophobicContact CB-CD1 3.65Å; P192-F361 HydrophobicContact CB-CD2 4.18Å; P192-F361 HydrophobicContact CB-CE1 3.64Å; P192-F361 HydrophobicContact CB-CE2 4.16Å; P192-F361 HydrophobicContact CB-CG 3.92Å; P192-F361 HydrophobicContact CB-CZ 3.89Å; P192-F364 HydrophobicContact CB-CB 3.79Å; P192-F364 HydrophobicContact CB-CD1 3.95Å; P192-F364 HydrophobicContact CB-CD2 4.37Å; P192-F364 HydrophobicContact CB-CG 3.79Å; P192-F364 HydrophobicContact CG-CB 3.94Å; P192-F364 HydrophobicContact CG-CG 4.31Å
193H95Very high93.1Very high108 Ų10846.7 Ų46.750%0.526%0.262SS..Hα-helixtrans-73.7-46.9176.5-62.6-100.4000111.1A190 E191 A197 F364A190-H193 WeakPolarHBondContact O-CA 3.38Å; A190-H193 WeakPolarHBondContact O-CB 3.49Å; A190-H193 PolarHBondContact O-N 3.34Å; E191-H193 PolarHBondContact O-N 3.29Å; H193-A197 WeakPolarHBondContact O-CB 3.35Å; H193-A197 PolarHBondContact O-N 2.98Å; H193-A197 VanDerWaalsContact O-N 3.08Å; H193-F364 HydrophobicContact CB-CE2 4.48Å; H193-F364 AromaticContact CD2-CD2 3.88Å; H193-F364 AromaticContact CE1-CD2 3.49Å; H193-F364 VanDerWaalsContact CE1-CD2 3.49Å; H193-F364 WeakPolarHBondContact CE1-CD2 3.34Å; H193-F364 AromaticContact CE1-CE2 3.81Å; H193-F364 AromaticContact CG-CD2 3.9Å; H193-F364 AromaticContact CG-CE2 3.86Å; H193-F364 AromaticContact ND1-CD2 3.66Å; H193-F364 AromaticContact ND1-CE2 3.52Å; H193-F364 AromaticContact NE2-CD2 3.61Å
194V95.3Very high91.6Very high71 Ų7149.2 Ų49.243%0.4329%0.288SS..Hα-helixtrans-66-49.9-179.4176.10000110.3C97 A190 E191 H196 A197 Y198C97-V194 HydrophobicContact CB-CG1 3.93Å; A190-V194 HydrophobicContact CB-CG2 4.39Å; A190-V194 WeakPolarHBondContact O-CG2 3.48Å; A190-V194 PolarHBondContact O-N 3Å; E191-V194 PolarHBondContact O-N 3.47Å; V194-H196 VanDerWaalsContact C-N 3.32Å; V194-H196 PolarHBondContact O-N 2.97Å; V194-A197 PolarHBondContact O-N 3.46Å; V194-Y198 WeakPolarHBondContact O-CB 3.4Å; V194-Y198 PolarHBondContact O-N 3.11Å
195L93.1Very high90.2Very high14 Ų1453.3 Ų53.37%0.07331%0.307CS..Hα-helixtrans-59.5-43.1-179.8-176.662.1000112D98 E191 R199 F361D98-L195 HydrophobicContact CB-CD1 3.6Å; E191-L195 VanDerWaalsContact O-CB 3.27Å; E191-L195 WeakPolarHBondContact O-CB 3.27Å; E191-L195 PolarHBondContact O-N 2.95Å; L195-R199 HydrophobicContact CD1-CG 4.27Å; L195-R199 WeakPolarHBondContact O-CB 3.38Å; L195-R199 WeakPolarHBondContact O-CG 3.47Å; L195-R199 PolarHBondContact O-N 3.2Å; L195-F361 HydrophobicContact CD2-CE1 4.14Å; L195-F361 HydrophobicContact CD2-CZ 3.71Å
196H92.4Very high88.7Confident64 Ų6454.2 Ų54.230%0.29632%0.315SS..Hα-helixtrans-61.8-51.6176.4-178.660.4000111.2P192 V194 Y198 R199 M200 F364 R368P192-H196 VanDerWaalsContact O-CB 3.25Å; P192-H196 WeakPolarHBondContact O-CB 3.32Å; P192-H196 PolarHBondContact O-N 3.29Å; V194-H196 VanDerWaalsContact C-N 3.32Å; V194-H196 PolarHBondContact O-N 2.97Å; H196-Y198 VanDerWaalsContact C-N 3.32Å; H196-Y198 PolarHBondContact O-N 2.88Å; H196-R199 PolarHBondContact O-N 3.47Å; H196-M200 VanDerWaalsContact O-CG 3.24Å; H196-M200 WeakPolarHBondContact O-CG 3.23Å; H196-M200 PolarHBondContact O-N 3.06Å; H196-F364 HydrophobicContact CB-CE1 4.29Å; H196-F364 HydrophobicContact CB-CZ 4.02Å; H196-R368 PolarHBondContact CD2-NH1 2.72Å; H196-R368 PolarHBondContact CE1-NH1 2.99Å; H196-R368 PolarHBondContact NE2-NH1 3.27Å
197A92.7Very high87.2Confident49 Ų4958.3 Ų58.341%0.40534%0.341SS..Hα-helixtrans-60.8-42.3179.700000112.1H193 V194 M200 C201H193-A197 WeakPolarHBondContact O-CB 3.35Å; H193-A197 PolarHBondContact O-N 2.98Å; H193-A197 VanDerWaalsContact O-N 3.08Å; V194-A197 PolarHBondContact O-N 3.46Å; A197-M200 PolarHBondContact O-N 3.44Å; A197-C201 PolarHBondContact O-N 3.39Å; A197-C201 PolarHBondContact O-SG 3.43Å
198Y91.6Very high85.7Confident29 Ų2959 Ų5911%0.11435%0.353CS..Hα-helixtrans-60.7-49.4178.7179.2-102.9000112.1V194 H196 M200 C201 R202 S211 V212 C213V194-Y198 WeakPolarHBondContact O-CB 3.4Å; V194-Y198 PolarHBondContact O-N 3.11Å; H196-Y198 VanDerWaalsContact C-N 3.32Å; H196-Y198 PolarHBondContact O-N 2.88Å; Y198-M200 VanDerWaalsContact C-N 3.31Å; Y198-M200 PolarHBondContact O-N 2.69Å; Y198-C201 PolarHBondContact O-N 2.92Å; Y198-R202 WeakPolarHBondContact O-CB 3.48Å; Y198-R202 PolarHBondContact O-N 2.89Å; Y198-R202 PolarHBondContact OH-NH1 2.61Å; Y198-S211 WeakPolarHBondContact OH-CA 3.49Å; Y198-V212 HydrophobicContact CE2-CG2 3.84Å; Y198-V212 PolarHBondContact OH-N 3.27Å; Y198-C213 HydrophobicContact CE2-CB 4.32Å
199R89.5Confident84.5Confident127 Ų12760.4 Ų60.448%0.47936%0.363SS..Hα-helixtrans-65.2-32.9177.2-71.9179.9174.6174.70.9112.5D98 L195 H196 R202 A203D98-R199 IonicContact OD1-NH2 3.92Å; D98-R199 PolarHBondContact OD1-NH2 3.16Å; D98-R199 IonicContact OD2-CZ 2.71Å; D98-R199 VanDerWaalsContact OD2-CZ 3.28Å; D98-R199 IonicContact OD2-NE 3.38Å; D98-R199 PolarHBondContact OD2-NE 3.31Å; D98-R199 IonicContact OD2-NH2 2.98Å; D98-R199 PolarHBondContact OD2-NH2 3.04Å; L195-R199 HydrophobicContact CD1-CG 4.27Å; L195-R199 WeakPolarHBondContact O-CB 3.38Å; L195-R199 WeakPolarHBondContact O-CG 3.47Å; L195-R199 PolarHBondContact O-N 3.2Å; H196-R199 PolarHBondContact O-N 3.47Å; R199-R202 CarbonylContact O-C 3.42Å; R199-R202 PolarHBondContact O-N 3.28Å; R199-A203 PolarHBondContact O-N 3.34Å
200M88.7Confident83.7Confident123 Ų12362 Ų6261%0.60637%0.37SS*.Hα-helixtrans-69.2-38.2174-67.1-62.394.300112.5H196 A197 Y198 R202H196-M200 VanDerWaalsContact O-CG 3.24Å; H196-M200 WeakPolarHBondContact O-CG 3.23Å; H196-M200 PolarHBondContact O-N 3.06Å; A197-M200 PolarHBondContact O-N 3.44Å; Y198-M200 VanDerWaalsContact C-N 3.31Å; Y198-M200 PolarHBondContact O-N 2.69Å; M200-R202 VanDerWaalsContact C-N 3.26Å; M200-R202 PolarHBondContact O-N 2.87Å
201C87.9Confident83.3Confident112 Ų11261.6 Ų61.676%0.75737%0.365SS*.Hα-helixtrans-72.9-20175.9-63.30000112.8A197 Y198A197-C201 PolarHBondContact O-N 3.39Å; A197-C201 PolarHBondContact O-SG 3.43Å; Y198-C201 PolarHBondContact O-N 2.92Å
202R80.8Confident82.9Confident45 Ų4565.3 Ų65.317%0.1739%0.388CS..THydrogen-bonded Turntrans-121.446.7-176.5-60.8-167.875.9-160.9-4.9112.9Y198 R199 M200 G204 Q205 D210 V212Y198-R202 WeakPolarHBondContact O-CB 3.48Å; Y198-R202 PolarHBondContact O-N 2.89Å; Y198-R202 PolarHBondContact OH-NH1 2.61Å; R199-R202 CarbonylContact O-C 3.42Å; R199-R202 PolarHBondContact O-N 3.28Å; M200-R202 VanDerWaalsContact C-N 3.26Å; M200-R202 PolarHBondContact O-N 2.87Å; R202-G204 PolarHBondContact O-N 2.82Å; R202-Q205 HydrophobicContact CB-CG 4.02Å; R202-Q205 PolarHBondContact O-N 3.05Å; R202-D210 PolarHBondContact NH1-O 3.3Å; R202-D210 VanDerWaalsContact NH1-O 3.11Å; R202-V212 VanDerWaalsContact CD-CG2 3.44Å; R202-V212 VanDerWaalsContact NH2-CG1 3.34Å
203A72Confident82.8Confident90 Ų9068.8 Ų68.874%0.74441%0.411SS*.THydrogen-bonded Turntrans-58.4124.2175.700000111R199R199-A203 PolarHBondContact O-N 3.34Å
204G66.8Low82.8Confident53 Ų5368.2 Ų68.255%0.54641%0.408SS..THydrogen-bonded Turntrans94.410.1174.800000116.4R202 R283R202-G204 PolarHBondContact O-N 2.82Å; G204-R283 PolarHBondContact O-NH2 2.8Å
205Q68.6Low83Confident85 Ų8568.6 Ų68.640%0.39741%0.405SS..PPolyproline II helixtrans-75.7142.3168.4-70.9-69.5-47.600111.4R202R202-Q205 HydrophobicContact CB-CG 4.02Å; R202-Q205 PolarHBondContact O-N 3.05Å
206P67.6Low83.2Confident32 Ų3268.7 Ų68.721%0.20841%0.406CS..PPolyproline II helixtrans-61.7148175.7-1727.2000112.1G208 S209 E279P206-G208 PolarHBondContact O-N 3.23Å; P206-S209 WeakPolarHBondContact O-CB 3.24Å; P206-S209 PolarHBondContact O-N 3.05Å; P206-S209 PolarHBondContact O-OG 3.34Å; P206-E279 WeakPolarHBondContact CG-OE1 3.39Å
207P65.6Low83.5Confident100 Ų10066.1 Ų66.165%0.64939%0.394SS*.THydrogen-bonded Turntrans-52.4133.2165.8-23.533.8000111.2
208G66.8Low83.7Confident34 Ų3463.8 Ų63.835%0.35138%0.375SS..THydrogen-bonded Turntrans74.519.6179.200000115.2P206P206-G208 PolarHBondContact O-N 3.23Å
209S74.5Confident84Confident29 Ų2962.4 Ų62.420%0.20337%0.369CS..PPolyproline II helixtrans-65.1145.4164.467.10000110.9P206P206-S209 WeakPolarHBondContact O-CB 3.24Å; P206-S209 PolarHBondContact O-N 3.05Å; P206-S209 PolarHBondContact O-OG 3.34Å
210D79.9Confident84.4Confident85 Ų8556.5 Ų56.546%0.45535%0.347SS..PPolyproline II helixtrans-59152.4175.4-68.2-37.4000112.1R202 V212R202-D210 PolarHBondContact NH1-O 3.3Å; R202-D210 VanDerWaalsContact NH1-O 3.11Å; D210-V212 PolarHBondContact O-N 3.42Å
211S87.6Confident84.8Confident29 Ų2950.6 Ų50.620%0.20332%0.318CS..PPolyproline II helixtrans-65.6132.1174.7-169.90000109.9T95 Y198 C213T95-S211 WeakPolarHBondContact O-CB 3.01Å; T95-S211 PolarHBondContact O-OG 2.74Å; Y198-S211 WeakPolarHBondContact OH-CA 3.49Å; S211-C213 PolarHBondContact OG-N 3.08Å; S211-C213 PolarHBondContact OG-O 2.99Å
212V88.6Confident85.3Confident91 Ų9145.4 Ų45.455%0.55228%0.283SS*.SBendtrans-90.3-13.4169.9-66.80000112.4Y198 R202 D210Y198-V212 HydrophobicContact CE2-CG2 3.84Å; Y198-V212 PolarHBondContact OH-N 3.27Å; R202-V212 VanDerWaalsContact CD-CG2 3.44Å; R202-V212 VanDerWaalsContact NH2-CG1 3.34Å; D210-V212 PolarHBondContact O-N 3.42Å
213C93.1Very high86.1Confident74 Ų7443.4 Ų43.450%0.528%0.276SS..  trans-109.3139.9-179.6-60.60000109.5Y198 S211Y198-C213 HydrophobicContact CE2-CB 4.32Å; S211-C213 PolarHBondContact OG-N 3.08Å; S211-C213 PolarHBondContact OG-O 2.99Å
214F96.6Very high87.3Confident96 Ų9640.3 Ų40.342%0.42125%0.247SC..  trans-136.9157.316171.3-85.6000108.1L93 V94 L262L93-F214 HydrophobicContact CD1-CD2 4.1Å; V94-F214 CarbonylContact O-C 3.52Å; V94-F214 WeakPolarHBondContact O-CA 3.39Å; V94-F214 WeakPolarHBondContact O-CB 3.4Å; F214-L262 HydrophobicContact CB-CD1 4.25Å; F214-L262 HydrophobicContact CB-CD2 3.6Å; F214-L262 HydrophobicContact CD1-CD1 3.5Å; F214-L262 HydrophobicContact CD1-CD2 4.06Å; F214-L262 HydrophobicContact CD1-CG 4.44Å; F214-L262 HydrophobicContact CD2-CD1 3.57Å; F214-L262 HydrophobicContact CD2-CD2 4.44Å; F214-L262 HydrophobicContact CE1-CD1 3.59Å; F214-L262 HydrophobicContact CE2-CD1 3.65Å; F214-L262 HydrophobicContact CG-CD1 3.49Å; F214-L262 VanDerWaalsContact CG-CD1 3.49Å; F214-L262 HydrophobicContact CG-CD2 3.79Å; F214-L262 HydrophobicContact CG-CG 4.28Å; F214-L262 HydrophobicContact CZ-CD1 3.66Å
215E97.8Very high88.6Confident80 Ų8045.1 Ų45.137%0.37425%0.248SC..EExtended strand (participates in β ladder)trans-143.6134.9179-156.3170.7-170.100110.5L93 V94 L217 R236L93-E215 WeakPolarHBondContact CA-O 3.32Å; V94-E215 PolarHBondContact N-O 2.85Å; V94-E215 PolarHBondContact O-N 2.93Å; E215-L217 HydrophobicContact CB-CD2 4.43Å; E215-L217 HydrophobicContact CG-CD2 3.72Å; E215-L217 HydrophobicContact CG-CG 4.31Å; E215-R236 WeakPolarHBondContact OE1-CB 3.29Å
216V98.3Very high89.9Confident16 Ų1649 Ų4910%0.09726%0.264CS..EExtended strand (participates in β ladder)trans-101.4107.4170.5-179.40000107.9Y91 I92 L93 P238 F240 V254 A258Y91-V216 HydrophobicContact CD1-CG1 4.26Å; I92-V216 CarbonylContact O-C 3.55Å; I92-V216 WeakPolarHBondContact O-CA 3.4Å; L93-V216 HydrophobicContact CD1-CG2 3.93Å; V216-P238 WeakPolarHBondContact O-CD 3.48Å; V216-F240 HydrophobicContact CB-CZ 4.37Å; V216-F240 HydrophobicContact CG1-CZ 3.9Å; V216-V254 HydrophobicContact CG1-CG1 3.77Å; V216-A258 HydrophobicContact CG2-CB 4.39Å
217L98.3Very high91.2Very high9 Ų949 Ų495%0.04726%0.262CS..EExtended strand (participates in β ladder)trans-97.3138.4-177.1-59174.7000110.5Y91 I92 V94 L187 E215 F219 I234 R236Y91-L217 WeakPolarHBondContact CA-O 3.42Å; I92-L217 HydrophobicContact CB-CB 4.4Å; I92-L217 PolarHBondContact N-O 3.24Å; I92-L217 PolarHBondContact O-N 2.99Å; V94-L217 HydrophobicContact CG2-CD1 4.19Å; L187-L217 HydrophobicContact CD2-CD1 3.89Å; E215-L217 HydrophobicContact CB-CD2 4.43Å; E215-L217 HydrophobicContact CG-CD2 3.72Å; E215-L217 HydrophobicContact CG-CG 4.31Å; L217-F219 HydrophobicContact CB-CD2 4.09Å; L217-F219 HydrophobicContact CB-CE2 3.81Å; L217-F219 HydrophobicContact CD1-CE2 4Å; L217-I234 HydrophobicContact CB-CG2 4.22Å; L217-I234 HydrophobicContact CD1-CG2 4.39Å; L217-I234 HydrophobicContact CD2-CG2 4.4Å; L217-R236 HydrophobicContact CD2-CB 4.44Å; L217-R236 HydrophobicContact CD2-CG 4.27Å
218G97.9Very high92.7Very high0 Ų047 Ų470%024%0.243CC..EExtended strand (participates in β ladder)trans-97.8110169.200000110.8N235G218-N235 PolarHBondContact N-O 3.11Å; G218-N235 WeakPolarHBondContact O-CB 3.3Å; G218-N235 PolarHBondContact O-N 3.33Å
219F98.1Very high94.2Very high0 Ų045.8 Ų45.80%023%0.229CC..EExtended strand (participates in β ladder)trans-88.5127.4174.8-82.7-117000109.9L88 R89 I90 I92 L182 V183 T186 L187 L217 I221 L231 I234L88-F219 VanDerWaalsContact O-O 3.14Å; R89-F219 WeakPolarHBondContact CA-O 3.3Å; I90-F219 HydrophobicContact CB-CB 4.46Å; I90-F219 PolarHBondContact N-O 2.92Å; I90-F219 PolarHBondContact O-N 3.33Å; I92-F219 HydrophobicContact CB-CD2 4Å; I92-F219 HydrophobicContact CB-CE2 3.91Å; I92-F219 HydrophobicContact CG1-CD2 3.4Å; I92-F219 VanDerWaalsContact CG1-CD2 3.4Å; I92-F219 HydrophobicContact CG1-CE2 3.65Å; I92-F219 HydrophobicContact CG1-CG 4.04Å; I92-F219 HydrophobicContact CG1-CZ 4.45Å; I92-F219 HydrophobicContact CG2-CE2 4.4Å; L182-F219 HydrophobicContact CD2-CD1 4.35Å; V183-F219 HydrophobicContact CB-CE1 4.46Å; V183-F219 HydrophobicContact CG1-CE1 4.34Å; V183-F219 HydrophobicContact CG1-CZ 4.16Å; V183-F219 HydrophobicContact CG2-CD1 4.06Å; V183-F219 HydrophobicContact CG2-CE1 4.17Å; V183-F219 HydrophobicContact CG2-CG 4.5Å; T186-F219 HydrophobicContact CG2-CE1 3.92Å; T186-F219 HydrophobicContact CG2-CZ 4.32Å; L187-F219 HydrophobicContact CG-CZ 4.36Å; L217-F219 HydrophobicContact CB-CD2 4.09Å; L217-F219 HydrophobicContact CB-CE2 3.81Å; L217-F219 HydrophobicContact CD1-CE2 4Å; F219-I221 HydrophobicContact CB-CD1 4.28Å; F219-I221 HydrophobicContact CB-CG1 4.38Å; F219-L231 HydrophobicContact CD1-CD1 3.75Å; F219-L231 HydrophobicContact CE1-CD1 4.24Å; F219-I234 HydrophobicContact CD1-CG1 4.22Å; F219-I234 HydrophobicContact CD2-CG2 4.11Å; F219-I234 HydrophobicContact CE1-CD1 3.98Å; F219-I234 HydrophobicContact CE1-CG1 3.97Å; F219-I234 HydrophobicContact CE2-CG1 4.47Å; F219-I234 HydrophobicContact CE2-CG2 3.8Å; F219-I234 HydrophobicContact CZ-CD1 3.92Å; F219-I234 HydrophobicContact CZ-CG1 4.1Å; F219-I234 HydrophobicContact CZ-CG2 4.15Å
220D96.8Very high95.3Very high3 Ų346.4 Ų46.42%0.01623%0.227CC..EExtended strand (participates in β ladder)trans-101.6112.7175.4-68.928.2000107.9L88 R89 R111 L232 E233 N235L88-D220 WeakPolarHBondContact O-CA 3.46Å; R89-D220 IonicContact CZ-OD1 2.97Å; R89-D220 IonicContact CZ-OD2 3.55Å; R89-D220 IonicContact NE-OD1 3.45Å; R89-D220 PolarHBondContact NE-OD1 3.42Å; R89-D220 IonicContact NH2-OD1 3.59Å; R89-D220 PolarHBondContact NH2-OD1 2.94Å; R89-D220 IonicContact NH2-OD2 2.59Å; R89-D220 PolarHBondContact NH2-OD2 3.45Å; R111-D220 IonicContact CZ-OD2 2.83Å; R111-D220 IonicContact NH1-OD2 2.67Å; R111-D220 VanDerWaalsContact NH2-CG 3.31Å; R111-D220 IonicContact NH2-OD1 3.3Å; R111-D220 IonicContact NH2-OD2 2.83Å; R111-D220 PolarHBondContact NH2-OD2 3.22Å; D220-L232 HydrophobicContact CB-CB 4.3Å; D220-L232 WeakPolarHBondContact O-CB 3.45Å; D220-L232 PolarHBondContact O-N 3.4Å; D220-E233 HydrophobicContact CB-CG 3.58Å; D220-E233 PolarHBondContact N-O 3.36Å; D220-N235 PolarHBondContact OD1-ND2 3.21Å; D220-N235 VanDerWaalsContact OD1-ND2 3.12Å; D220-N235 PolarHBondContact OD2-ND2 2.83Å
221I98Very high96.2Very high0 Ų043.3 Ų43.30%021%0.21CC..EExtended strand (participates in β ladder)trans-123135.8-172.8-64.3173.5000109.5L88 I90 I179 L182 F219 L223 P229 W230L88-I221 HydrophobicContact CB-CB 4.42Å; L88-I221 PolarHBondContact N-O 3.14Å; L88-I221 PolarHBondContact O-N 3.43Å; I90-I221 HydrophobicContact CD1-CD1 3.95Å; I90-I221 HydrophobicContact CG1-CD1 4.42Å; I179-I221 HydrophobicContact CD1-CD1 3.68Å; I179-I221 HydrophobicContact CD1-CG2 3.81Å; I179-I221 HydrophobicContact CG2-CD1 4.44Å; L182-I221 HydrophobicContact CD1-CD1 4.44Å; L182-I221 HydrophobicContact CD2-CD1 3.98Å; L182-I221 HydrophobicContact CD2-CG1 4.45Å; F219-I221 HydrophobicContact CB-CD1 4.28Å; F219-I221 HydrophobicContact CB-CG1 4.38Å; I221-L223 HydrophobicContact CG2-CD2 4.43Å; I221-P229 HydrophobicContact CG2-CB 3.69Å; I221-W230 WeakPolarHBondContact CA-O 3.35Å
222L97.6Very high96.5Very high3 Ų344 Ų442%0.01621%0.211CC..EExtended strand (participates in β ladder)trans-108.2136.6171.2-164.575.8000109.9L75 P78 F86 D87 W230 L232L75-L222 HydrophobicContact CB-CD2 3.72Å; L75-L222 HydrophobicContact CD1-CB 4.23Å; L75-L222 HydrophobicContact CD1-CD2 3.57Å; L75-L222 HydrophobicContact CD1-CG 4.43Å; L75-L222 HydrophobicContact CG-CD2 4.27Å; P78-L222 HydrophobicContact CB-CD2 4.33Å; F86-L222 WeakPolarHBondContact O-CD1 3.42Å; D87-L222 HydrophobicContact CB-CD1 4.32Å; L222-W230 PolarHBondContact N-O 3.43Å; L222-W230 WeakPolarHBondContact O-CB 3.26Å; L222-W230 PolarHBondContact O-N 2.97Å; L222-L232 HydrophobicContact CB-CD1 4.03Å; L222-L232 HydrophobicContact CB-CD2 4Å; L222-L232 HydrophobicContact CB-CG 4.07Å
223L97.7Very high96.7Very high2 Ų243.3 Ų43.31%0.0120%0.202CC..EExtended strand (participates in β ladder)trans-92.1133.9170.1-57.4-175.5000109.8P78 F79 F86 L88 F161 F175 I221 L227 P229P78-L223 CarbonylContact C-O 3.58Å; P78-L223 WeakPolarHBondContact CA-O 3.47Å; F79-L223 HydrophobicContact CB-CB 3.93Å; F79-L223 PolarHBondContact N-O 3.1Å; F86-L223 HydrophobicContact CE2-CD1 4.4Å; F86-L223 HydrophobicContact CZ-CD1 4.35Å; L88-L223 HydrophobicContact CD1-CD1 4.03Å; L88-L223 HydrophobicContact CD1-CD2 4.21Å; L88-L223 HydrophobicContact CD1-CG 4Å; F161-L223 HydrophobicContact CE1-CD1 3.91Å; F161-L223 HydrophobicContact CZ-CD1 3.62Å; F175-L223 HydrophobicContact CD2-CD1 4.23Å; F175-L223 HydrophobicContact CD2-CD2 4.42Å; F175-L223 HydrophobicContact CE2-CD1 3.91Å; F175-L223 HydrophobicContact CE2-CD2 4.07Å; I221-L223 HydrophobicContact CG2-CD2 4.43Å; L223-L227 HydrophobicContact CD1-CD2 3.86Å; L223-P229 HydrophobicContact CD2-CB 3.88Å
224D96.4Very high96.8Very high25 Ų2543 Ų4313%0.13419%0.194CC..BIsolated β-bridgetrans-81.8170.7166.975.223.2000111.8F79 K226 L227 K228 W230F79-D224 WeakPolarHBondContact CB-O 3.39Å; F79-D224 VanDerWaalsContact N-C 3.33Å; D224-K226 PolarHBondContact O-N 3.5Å; D224-K226 WeakPolarHBondContact OD1-CA 3.47Å; D224-K226 WeakPolarHBondContact OD1-CB 3.32Å; D224-K226 PolarHBondContact OD1-N 2.99Å; D224-L227 WeakPolarHBondContact O-CA 3.4Å; D224-L227 PolarHBondContact O-N 3.1Å; D224-L227 PolarHBondContact OD1-N 3.36Å; D224-K228 PolarHBondContact N-O 2.64Å; D224-K228 WeakPolarHBondContact OD1-CB 3.33Å; D224-K228 PolarHBondContact OD1-N 3.48Å; D224-K228 VanDerWaalsContact OD1-N 3.13Å; D224-K228 WeakPolarHBondContact OD2-CB 3.44Å; D224-W230 PolarHBondContact OD2-NE1 3.39Å
225R95.5Very high96.7Very high154 Ų15440.5 Ų40.558%0.58119%0.186SC*.THydrogen-bonded Turntrans-54.8-14179.864.3170177.2168.37.4115.6K77K77-R225 HydrophobicContact CB-CG 4.11Å; K77-R225 PolarHBondContact O-N 3.07Å
226K95Very high96.5Very high167 Ų16746 Ų4673%0.72620%0.203SC*.THydrogen-bonded Turntrans-10114.1175.4-59.6-173.4174.2-1700112.1D224 K228D224-K226 PolarHBondContact O-N 3.5Å; D224-K226 WeakPolarHBondContact OD1-CA 3.47Å; D224-K226 WeakPolarHBondContact OD1-CB 3.32Å; D224-K226 PolarHBondContact OD1-N 2.99Å; K226-K228 PolarHBondContact O-N 3.42Å
227L95.6Very high96Very high32 Ų3249.6 Ų49.617%0.16824%0.235CC..  trans59.318.5-173.4-65.4170.6000114.3F79 L165 C170 L223 D224 P229F79-L227 HydrophobicContact CB-CD2 4.35Å; F79-L227 HydrophobicContact CD1-CD2 3.85Å; F79-L227 HydrophobicContact CD2-CD2 3.57Å; F79-L227 HydrophobicContact CD2-CG 4.05Å; F79-L227 HydrophobicContact CE1-CD2 3.94Å; F79-L227 HydrophobicContact CE2-CD2 3.68Å; F79-L227 HydrophobicContact CE2-CG 4.07Å; F79-L227 HydrophobicContact CG-CD2 3.66Å; F79-L227 HydrophobicContact CZ-CD2 3.87Å; L165-L227 HydrophobicContact CD2-CD1 4.22Å; L165-L227 HydrophobicContact CD2-CD2 3.99Å; C170-L227 HydrophobicContact CB-CD1 3.72Å; L223-L227 HydrophobicContact CD1-CD2 3.86Å; D224-L227 WeakPolarHBondContact O-CA 3.4Å; D224-L227 PolarHBondContact O-N 3.1Å; D224-L227 PolarHBondContact OD1-N 3.36Å; L227-P229 WeakPolarHBondContact O-CD 3.45Å
228K97.1Very high95.7Very high59 Ų5949.6 Ų49.626%0.25724%0.235SC..  trans-73.9128.6173.5-178.6-172.1174.4-171.50109.1N10 D224 K226 W230N10-K228 PolarHBondContact O-NZ 3.24Å; N10-K228 VanDerWaalsContact OD1-CE 3.22Å; N10-K228 WeakPolarHBondContact OD1-CE 3.47Å; N10-K228 PolarHBondContact OD1-NZ 3.36Å; D224-K228 PolarHBondContact N-O 2.64Å; D224-K228 WeakPolarHBondContact OD1-CB 3.33Å; D224-K228 PolarHBondContact OD1-N 3.48Å; D224-K228 VanDerWaalsContact OD1-N 3.13Å; D224-K228 WeakPolarHBondContact OD2-CB 3.44Å; K226-K228 PolarHBondContact O-N 3.42Å; K228-W230 HydrophobicContact CD-CZ2 4.09Å; K228-W230 VanDerWaalsContact O-CD1 3.22Å
229P98.1Very high95.3Very high7 Ų753.5 Ų53.55%0.04526%0.262CS..EExtended strand (participates in β ladder)trans-78.8137.317732.1-34.6000112.2D178 I179 L182 I221 L223 L227D178-P229 HydrophobicContact CB-CG 3.72Å; I179-P229 HydrophobicContact CD1-CB 3.54Å; I179-P229 HydrophobicContact CD1-CG 4.17Å; I179-P229 HydrophobicContact CG1-CB 4.43Å; L182-P229 HydrophobicContact CD1-CB 3.85Å; L182-P229 HydrophobicContact CD1-CG 4.12Å; I221-P229 HydrophobicContact CG2-CB 3.69Å; L223-P229 HydrophobicContact CD2-CB 3.88Å; L227-P229 WeakPolarHBondContact O-CD 3.45Å
230W98.4Very high95.1Very high43 Ų4356.8 Ų56.816%0.16328%0.277CS..EExtended strand (participates in β ladder)trans-122123.7176.7-67.185.6000110.1N10 F11 P13 L75 I221 L222 D224 K228 L232N10-W230 WeakPolarHBondContact O-CZ3 3.29Å; F11-W230 CarbonylContact O-C 3.54Å; F11-W230 VanDerWaalsContact O-CA 3.26Å; F11-W230 WeakPolarHBondContact O-CA 3.47Å; P13-W230 HydrophobicContact CG-CE3 4.03Å; L75-W230 HydrophobicContact CD1-CB 3.5Å; L75-W230 HydrophobicContact CD1-CD2 4.03Å; L75-W230 HydrophobicContact CD1-CG 3.54Å; L75-W230 HydrophobicContact CD2-CD2 3.82Å; L75-W230 HydrophobicContact CD2-CE3 4.17Å; L75-W230 HydrophobicContact CD2-CG 4.14Å; L75-W230 HydrophobicContact CD2-CZ2 4.28Å; I221-W230 WeakPolarHBondContact CA-O 3.35Å; L222-W230 PolarHBondContact N-O 3.43Å; L222-W230 WeakPolarHBondContact O-CB 3.26Å; L222-W230 PolarHBondContact O-N 2.97Å; D224-W230 PolarHBondContact OD2-NE1 3.39Å; K228-W230 HydrophobicContact CD-CZ2 4.09Å; K228-W230 VanDerWaalsContact O-CD1 3.22Å; W230-L232 PolarHBondContact O-N 2.88Å
231L97.9Very high94.8Very high19 Ų1958.3 Ų58.310%0.09929%0.293CS..EExtended strand (participates in β ladder)trans-72.2123.7175.8179.665.7000109.8F11 T12 P13 L182 T186 F219 I234F11-L231 HydrophobicContact CD2-CB 4.15Å; F11-L231 HydrophobicContact CE2-CD2 4.45Å; F11-L231 PolarHBondContact O-N 2.87Å; T12-L231 HydrophobicContact CG2-CB 4.28Å; T12-L231 HydrophobicContact CG2-CD2 4.29Å; P13-L231 WeakPolarHBondContact CD-O 3.2Å; L182-L231 HydrophobicContact CD1-CB 4.29Å; L182-L231 HydrophobicContact CD2-CB 4.13Å; L182-L231 HydrophobicContact CD2-CD1 4.19Å; L182-L231 HydrophobicContact CG-CB 4.47Å; T186-L231 HydrophobicContact CG2-CD2 3.69Å; F219-L231 HydrophobicContact CD1-CD1 3.75Å; F219-L231 HydrophobicContact CE1-CD1 4.24Å; L231-I234 HydrophobicContact CD1-CG1 4.07Å; L231-I234 HydrophobicContact CD2-CD1 4.47Å; L231-I234 HydrophobicContact CD2-CG1 4.49Å
232L94Very high94.4Very high45 Ų4561.8 Ų61.824%0.23631%0.314CS..EExtended strand (participates in β ladder)trans-95.9-52.8175.3-58.7-173.5000111.9L75 D220 L222 W230L75-L232 HydrophobicContact CD1-CD2 4.42Å; D220-L232 HydrophobicContact CB-CB 4.3Å; D220-L232 WeakPolarHBondContact O-CB 3.45Å; D220-L232 PolarHBondContact O-N 3.4Å; L222-L232 HydrophobicContact CB-CD1 4.03Å; L222-L232 HydrophobicContact CB-CD2 4Å; L222-L232 HydrophobicContact CB-CG 4.07Å; W230-L232 PolarHBondContact O-N 2.88Å
233E92.8Very high93.8Very high76 Ų7667.2 Ų67.236%0.35534%0.344SS..EExtended strand (participates in β ladder)trans-160.9164.5-178.659.6-179.9-137.500111.4D220 N235D220-E233 HydrophobicContact CB-CG 3.58Å; D220-E233 PolarHBondContact N-O 3.36Å; E233-N235 PolarHBondContact OE1-ND2 3.43Å
234I95.8Very high93.1Very high66 Ų6668.7 Ų68.734%0.33835%0.35SS..EExtended strand (participates in β ladder)trans-123.9119.7174.7-51.9169.3000107.9T186 L217 F219 L231T186-I234 HydrophobicContact CG2-CD1 3.35Å; T186-I234 HydrophobicContact CG2-CG1 4.44Å; L217-I234 HydrophobicContact CB-CG2 4.22Å; L217-I234 HydrophobicContact CD1-CG2 4.39Å; L217-I234 HydrophobicContact CD2-CG2 4.4Å; F219-I234 HydrophobicContact CD1-CG1 4.22Å; F219-I234 HydrophobicContact CD2-CG2 4.11Å; F219-I234 HydrophobicContact CE1-CD1 3.98Å; F219-I234 HydrophobicContact CE1-CG1 3.97Å; F219-I234 HydrophobicContact CE2-CG1 4.47Å; F219-I234 HydrophobicContact CE2-CG2 3.8Å; F219-I234 HydrophobicContact CZ-CD1 3.92Å; F219-I234 HydrophobicContact CZ-CG1 4.1Å; F219-I234 HydrophobicContact CZ-CG2 4.15Å; L231-I234 HydrophobicContact CD1-CG1 4.07Å; L231-I234 HydrophobicContact CD2-CD1 4.47Å; L231-I234 HydrophobicContact CD2-CG1 4.49Å
235N93.9Very high92.7Very high45 Ų4573 Ų7324%0.24137%0.368CS..EExtended strand (participates in β ladder)trans-96111.1179.5-74.2-58.9000109.8R89 G218 D220 E233 A237R89-N235 PolarHBondContact NH2-ND2 2.77Å; R89-N235 VanDerWaalsContact NH2-ND2 3.19Å; G218-N235 PolarHBondContact N-O 3.11Å; G218-N235 WeakPolarHBondContact O-CB 3.3Å; G218-N235 PolarHBondContact O-N 3.33Å; D220-N235 PolarHBondContact OD1-ND2 3.21Å; D220-N235 VanDerWaalsContact OD1-ND2 3.12Å; D220-N235 PolarHBondContact OD2-ND2 2.83Å; E233-N235 PolarHBondContact OE1-ND2 3.43Å; N235-A237 VanDerWaalsContact C-N 3.31Å
236R92.6Very high92.4Very high194 Ų19467.6 Ų67.673%0.73235%0.35SS*.SBendtrans-70-28.2175.2-59.7-167.6-61.81702.7113.4E215 L217 P238E215-R236 WeakPolarHBondContact OE1-CB 3.29Å; L217-R236 HydrophobicContact CD2-CB 4.44Å; L217-R236 HydrophobicContact CD2-CG 4.27Å; R236-P238 VanDerWaalsContact C-CD 3.48Å; R236-P238 WeakPolarHBondContact O-CD 3.45Å
237A89.4Confident92.2Very high93 Ų9359.8 Ų59.877%0.76932%0.317SS*.SBendtrans-122.971.8177.200000109.3N235N235-A237 VanDerWaalsContact C-N 3.31Å
238P91.8Very high92.1Very high9 Ų963 Ų636%0.05833%0.327CS..  trans-63.8145.1176.128.9-33.1000110.3Y91 V216 R236 F240Y91-P238 HydrophobicContact CE1-CB 4.17Å; Y91-P238 HydrophobicContact CE1-CG 4.33Å; V216-P238 WeakPolarHBondContact O-CD 3.48Å; R236-P238 VanDerWaalsContact C-CD 3.48Å; R236-P238 WeakPolarHBondContact O-CD 3.45Å; P238-F240 HydrophobicContact CG-CE2 3.85Å; P238-F240 HydrophobicContact CG-CZ 3.79Å; P238-F240 VanDerWaalsContact O-CD2 3.28Å; P238-F240 WeakPolarHBondContact O-CD2 2.98Å; P238-F240 PolarHBondContact O-N 2.59Å
239S89.1Confident91.9Very high81 Ų8164 Ų6457%0.56634%0.335SS*.  trans-68.8121.3178.5173.80000111.5G241 K251S239-G241 PolarHBondContact OG-N 2.83Å; S239-K251 WeakPolarHBondContact O-CE 3.28Å; S239-K251 PolarHBondContact O-NZ 2.94Å
240F93Very high91.8Very high70 Ų7063.9 Ų63.931%0.30734%0.335SS..  trans-96.113.5172.9-66.6-72.4000113.9Y91 V216 P238 K251 V254 L255Y91-F240 HydrophobicContact CE1-CE1 4.1Å; V216-F240 HydrophobicContact CB-CZ 4.37Å; V216-F240 HydrophobicContact CG1-CZ 3.9Å; P238-F240 HydrophobicContact CG-CE2 3.85Å; P238-F240 HydrophobicContact CG-CZ 3.79Å; P238-F240 VanDerWaalsContact O-CD2 3.28Å; P238-F240 WeakPolarHBondContact O-CD2 2.98Å; P238-F240 PolarHBondContact O-N 2.59Å; F240-K251 HydrophobicContact CD1-CB 4.16Å; F240-K251 HydrophobicContact CD1-CG 4.28Å; F240-V254 HydrophobicContact CE1-CG1 4.21Å; F240-L255 HydrophobicContact CD1-CD1 3.94Å; F240-L255 HydrophobicContact CD1-CD2 4.16Å; F240-L255 HydrophobicContact CD1-CG 4.09Å; F240-L255 HydrophobicContact CE1-CD1 4.35Å; F240-L255 HydrophobicContact CE1-CD2 3.77Å; F240-L255 HydrophobicContact CE1-CG 4Å; F240-L255 HydrophobicContact CE2-CD2 4.26Å; F240-L255 HydrophobicContact CG-CD1 4.23Å; F240-L255 HydrophobicContact CZ-CD2 3.82Å
241G90.3Very high91.7Very high34 Ų3462.5 Ų62.535%0.35133%0.33SS..  trans-61.4143.9173.100000112S239 K251S239-G241 PolarHBondContact OG-N 2.83Å; G241-K251 PolarHBondContact O-NZ 2.91Å
242T90.2Very high91.7Very high73 Ų7366.5 Ų66.545%0.44835%0.346SS..  trans-122.562.4-170.746.70000111.5Q244 Y248 K251T242-Q244 VanDerWaalsContact C-N 3.32Å; T242-Q244 PolarHBondContact O-N 2.97Å; T242-Y248 HydrophobicContact CG2-CD2 4.32Å; T242-K251 HydrophobicContact CG2-CD 4.35Å
243D84.3Confident91.8Very high118 Ų11865 Ų6563%0.63134%0.342SS*.SBendtrans-69.8-29.4-178.4-59.7-13.6000112.4Y135Y135-D243 PolarHBondContact OH-OD2 2.91Å
244Q83.7Confident92Very high33 Ų3361.4 Ų61.415%0.15433%0.325CS..SBendtrans-121.4154.1179.9-59.5177.5-67.800110.9K155 T242 L246 D247 Y248K155-Q244 VanDerWaalsContact CE-OE1 3.27Å; T242-Q244 VanDerWaalsContact C-N 3.32Å; T242-Q244 PolarHBondContact O-N 2.97Å; Q244-L246 PolarHBondContact O-N 3.21Å; Q244-D247 WeakPolarHBondContact CB-OD2 3.43Å; Q244-D247 PolarHBondContact N-OD2 2.83Å; Q244-D247 WeakPolarHBondContact O-CB 3.01Å; Q244-D247 PolarHBondContact O-N 2.97Å; Q244-Y248 PolarHBondContact O-N 2.87Å; Q244-Y248 VanDerWaalsContact O-N 3.11Å
245K87.9Confident92.1Very high114 Ų11461.6 Ų61.650%0.49633%0.326SS..Hα-helixtrans-54.3-41.7175.9179.754.2173.2155.80112.5D247 Y248 D249K245-D247 VanDerWaalsContact C-N 3.34Å; K245-D247 PolarHBondContact O-N 3.26Å; K245-Y248 WeakPolarHBondContact O-CB 3.5Å; K245-Y248 PolarHBondContact O-N 2.72Å; K245-Y248 VanDerWaalsContact O-N 3.13Å; K245-D249 WeakPolarHBondContact CE-OD1 3.39Å; K245-D249 WeakPolarHBondContact CE-OD2 3.06Å; K245-D249 IonicContact NZ-OD1 2.94Å; K245-D249 PolarHBondContact NZ-OD1 3.4Å; K245-D249 IonicContact NZ-OD2 3.9Å; K245-D249 PolarHBondContact NZ-OD2 3.21Å; K245-D249 PolarHBondContact O-N 3.26Å
246L89.4Confident92.3Very high42 Ų4263.3 Ų63.322%0.2234%0.335CS..Hα-helixtrans-55.1-45.1173.1173.465.5000112.7L109 K155 Q244 Y248 D249 V250L109-L246 HydrophobicContact CD2-CG 4.34Å; K155-L246 HydrophobicContact CB-CD2 4.22Å; K155-L246 HydrophobicContact CD-CD2 3.98Å; K155-L246 HydrophobicContact CG-CD2 3.79Å; Q244-L246 PolarHBondContact O-N 3.21Å; L246-Y248 VanDerWaalsContact C-N 3.33Å; L246-D249 PolarHBondContact O-N 3.36Å; L246-V250 HydrophobicContact CD1-CG2 4.11Å; L246-V250 WeakPolarHBondContact O-CG2 3.44Å; L246-V250 PolarHBondContact O-N 2.99Å
247D90.8Very high92.5Very high3 Ų355.1 Ų55.12%0.01631%0.305CS..Hα-helixtrans-62.8-43.7177.5-68-65.5000110.4K155 Q244 K245 K251K155-D247 IonicContact NZ-OD1 3.75Å; K155-D247 PolarHBondContact NZ-OD1 2.83Å; K155-D247 IonicContact NZ-OD2 2.87Å; K155-D247 PolarHBondContact NZ-OD2 3.3Å; Q244-D247 WeakPolarHBondContact CB-OD2 3.43Å; Q244-D247 PolarHBondContact N-OD2 2.83Å; Q244-D247 WeakPolarHBondContact O-CB 3.01Å; Q244-D247 PolarHBondContact O-N 2.97Å; K245-D247 VanDerWaalsContact C-N 3.34Å; K245-D247 PolarHBondContact O-N 3.26Å; D247-K251 HydrophobicContact CB-CD 4.09Å; D247-K251 WeakPolarHBondContact O-CB 3.15Å; D247-K251 WeakPolarHBondContact O-CD 3.43Å; D247-K251 WeakPolarHBondContact O-CG 3.25Å; D247-K251 PolarHBondContact O-N 3.5Å; D247-K251 IonicContact OD1-NZ 3.5Å
248Y93.3Very high92.9Very high98 Ų9850.8 Ų50.838%0.38427%0.27SS..Hα-helixtrans-59.4-50.6178.4178.1-90.5000111.6T242 Q244 K245 L246 K252T242-Y248 HydrophobicContact CG2-CD2 4.32Å; Q244-Y248 PolarHBondContact O-N 2.87Å; Q244-Y248 VanDerWaalsContact O-N 3.11Å; K245-Y248 WeakPolarHBondContact O-CB 3.5Å; K245-Y248 PolarHBondContact O-N 2.72Å; K245-Y248 VanDerWaalsContact O-N 3.13Å; L246-Y248 VanDerWaalsContact C-N 3.33Å; Y248-K252 HydrophobicContact CE1-CD 3.67Å; Y248-K252 HydrophobicContact CE2-CD 4.48Å; Y248-K252 WeakPolarHBondContact O-CB 3.49Å; Y248-K252 PolarHBondContact O-N 3.04Å; Y248-K252 PolarHBondContact OH-NZ 3.13Å
249D93.4Very high93.1Very high80 Ų8054.8 Ų54.843%0.42829%0.29SS..Hα-helixtrans-64.4-45.9-174.6-67.1-29.5000111.8K245 L246 G253K245-D249 WeakPolarHBondContact CE-OD1 3.39Å; K245-D249 WeakPolarHBondContact CE-OD2 3.06Å; K245-D249 IonicContact NZ-OD1 2.94Å; K245-D249 PolarHBondContact NZ-OD1 3.4Å; K245-D249 IonicContact NZ-OD2 3.9Å; K245-D249 PolarHBondContact NZ-OD2 3.21Å; K245-D249 PolarHBondContact O-N 3.26Å; L246-D249 PolarHBondContact O-N 3.36Å; D249-G253 PolarHBondContact O-N 3.38Å
250V95.3Very high93.3Very high6 Ų655 Ų554%0.03628%0.282CS..Hα-helixtrans-66.7-51.5178175.50000110.8Y91 L109 L246 G253 V254Y91-V250 HydrophobicContact CD2-CG1 4.45Å; Y91-V250 HydrophobicContact CE2-CG1 4.04Å; L109-V250 HydrophobicContact CD2-CB 4.2Å; L109-V250 HydrophobicContact CD2-CG1 4.26Å; L109-V250 HydrophobicContact CD2-CG2 4.18Å; L246-V250 HydrophobicContact CD1-CG2 4.11Å; L246-V250 WeakPolarHBondContact O-CG2 3.44Å; L246-V250 PolarHBondContact O-N 2.99Å; V250-G253 PolarHBondContact O-N 3.09Å; V250-V254 HydrophobicContact CG1-CG2 4.48Å; V250-V254 WeakPolarHBondContact O-CG2 3.2Å; V250-V254 PolarHBondContact O-N 3.37Å
251K96.8Very high93.4Very high13 Ų1351.9 Ų51.96%0.05727%0.269CS..Hα-helixtrans-72.1-35.8-171.9-66169.1-176-166.50112.7S239 F240 G241 T242 D247 G253 V254 L255S239-K251 WeakPolarHBondContact O-CE 3.28Å; S239-K251 PolarHBondContact O-NZ 2.94Å; F240-K251 HydrophobicContact CD1-CB 4.16Å; F240-K251 HydrophobicContact CD1-CG 4.28Å; G241-K251 PolarHBondContact O-NZ 2.91Å; T242-K251 HydrophobicContact CG2-CD 4.35Å; D247-K251 HydrophobicContact CB-CD 4.09Å; D247-K251 WeakPolarHBondContact O-CB 3.15Å; D247-K251 WeakPolarHBondContact O-CD 3.43Å; D247-K251 WeakPolarHBondContact O-CG 3.25Å; D247-K251 PolarHBondContact O-N 3.5Å; D247-K251 IonicContact OD1-NZ 3.5Å; K251-G253 VanDerWaalsContact C-N 3.33Å; K251-V254 PolarHBondContact O-N 3.37Å; K251-L255 WeakPolarHBondContact O-CG 3.5Å; K251-L255 PolarHBondContact O-N 2.94Å
252K97.1Very high93.5Very high104 Ų10452.1 Ų52.145%0.45226%0.262SS..Hα-helixtrans-59.3-47.3171.5178.6-175.5179.8178.30110.2Y248 L255 L256Y248-K252 HydrophobicContact CE1-CD 3.67Å; Y248-K252 HydrophobicContact CE2-CD 4.48Å; Y248-K252 WeakPolarHBondContact O-CB 3.49Å; Y248-K252 PolarHBondContact O-N 3.04Å; Y248-K252 PolarHBondContact OH-NZ 3.13Å; K252-L255 PolarHBondContact O-N 2.87Å; K252-L256 VanDerWaalsContact O-CB 3.22Å; K252-L256 WeakPolarHBondContact O-CB 3.31Å; K252-L256 PolarHBondContact O-N 3.17Å
253G96.9Very high93.5Very high13 Ų1351.2 Ų51.213%0.13425%0.254CS..Hα-helixtrans-63.1-41.2179.300000112.9Y105 D249 V250 K251 L255 N257Y105-G253 WeakPolarHBondContact OH-CA 3.06Å; D249-G253 PolarHBondContact O-N 3.38Å; V250-G253 PolarHBondContact O-N 3.09Å; K251-G253 VanDerWaalsContact C-N 3.33Å; G253-L255 PolarHBondContact O-N 3.28Å; G253-N257 VanDerWaalsContact O-CB 3.25Å; G253-N257 WeakPolarHBondContact O-CB 3.49Å; G253-N257 VanDerWaalsContact O-CG 3.24Å; G253-N257 PolarHBondContact O-N 3.28Å; G253-N257 PolarHBondContact O-ND2 3.18Å
254V97.9Very high93.7Very high0 Ų051 Ų510%025%0.252CS..Hα-helixtrans-55.6-52.5173.2168.60000110.7Y91 Y105 V216 F240 V250 K251 A258 Y338Y91-V254 HydrophobicContact CD1-CG1 4.03Å; Y91-V254 HydrophobicContact CD1-CG2 4.33Å; Y91-V254 HydrophobicContact CD2-CG2 3.64Å; Y91-V254 HydrophobicContact CE2-CG2 4.25Å; Y91-V254 HydrophobicContact CG-CG1 4.04Å; Y91-V254 HydrophobicContact CG-CG2 3.69Å; Y105-V254 HydrophobicContact CD1-CG2 3.41Å; Y105-V254 VanDerWaalsContact CD1-CG2 3.41Å; Y105-V254 HydrophobicContact CD2-CG2 4.22Å; Y105-V254 HydrophobicContact CE1-CG2 3.54Å; Y105-V254 HydrophobicContact CE2-CG2 4.31Å; Y105-V254 HydrophobicContact CG-CG2 3.79Å; Y105-V254 PolarHBondContact OH-N 3.28Å; V216-V254 HydrophobicContact CG1-CG1 3.77Å; F240-V254 HydrophobicContact CE1-CG1 4.21Å; V250-V254 HydrophobicContact CG1-CG2 4.48Å; V250-V254 WeakPolarHBondContact O-CG2 3.2Å; V250-V254 PolarHBondContact O-N 3.37Å; K251-V254 PolarHBondContact O-N 3.37Å; V254-A258 WeakPolarHBondContact O-CB 3.34Å; V254-A258 PolarHBondContact O-N 3.42Å; V254-A258 VanDerWaalsContact O-N 3.14Å; V254-Y338 WeakPolarHBondContact CG1-OH 3.47Å; V254-Y338 PolarHBondContact O-OH 2.99Å
255L97.7Very high93.8Very high70 Ų7055.7 Ų55.737%0.36627%0.268SS..Hα-helixtrans-71.6-44.1-175.1-66.4173.8000112.6F240 K251 K252 G253 A258 L259F240-L255 HydrophobicContact CD1-CD1 3.94Å; F240-L255 HydrophobicContact CD1-CD2 4.16Å; F240-L255 HydrophobicContact CD1-CG 4.09Å; F240-L255 HydrophobicContact CE1-CD1 4.35Å; F240-L255 HydrophobicContact CE1-CD2 3.77Å; F240-L255 HydrophobicContact CE1-CG 4Å; F240-L255 HydrophobicContact CE2-CD2 4.26Å; F240-L255 HydrophobicContact CG-CD1 4.23Å; F240-L255 HydrophobicContact CZ-CD2 3.82Å; K251-L255 WeakPolarHBondContact O-CG 3.5Å; K251-L255 PolarHBondContact O-N 2.94Å; K252-L255 PolarHBondContact O-N 2.87Å; G253-L255 PolarHBondContact O-N 3.28Å; L255-A258 PolarHBondContact O-N 2.81Å; L255-L259 WeakPolarHBondContact O-CG 3.49Å; L255-L259 PolarHBondContact O-N 2.8Å
256L97.1Very high93.5Very high81 Ų8155.2 Ų55.242%0.42429%0.286SS..Hα-helixtrans-63.8-52.7-178-17764.6000111K252 A258 L259 E260K252-L256 VanDerWaalsContact O-CB 3.22Å; K252-L256 WeakPolarHBondContact O-CB 3.31Å; K252-L256 PolarHBondContact O-N 3.17Å; L256-A258 PolarHBondContact O-N 3.42Å; L256-L259 PolarHBondContact O-N 3.3Å; L256-L259 VanDerWaalsContact O-N 3.15Å; L256-E260 WeakPolarHBondContact O-CG 3.33Å; L256-E260 PolarHBondContact O-N 3.41Å
257N97.4Very high93.2Very high22 Ų2256.3 Ų56.312%0.11830%0.297CS..Hα-helixtrans-64.6-30.7179.7-64.2-35.5000111.5Y105 G253 L261 N337 Y338Y105-N257 HydrophobicContact CE2-CB 4.45Å; G253-N257 VanDerWaalsContact O-CB 3.25Å; G253-N257 WeakPolarHBondContact O-CB 3.49Å; G253-N257 VanDerWaalsContact O-CG 3.24Å; G253-N257 PolarHBondContact O-N 3.28Å; G253-N257 PolarHBondContact O-ND2 3.18Å; N257-L261 WeakPolarHBondContact O-CB 3.48Å; N257-L261 WeakPolarHBondContact O-CG 3.42Å; N257-L261 PolarHBondContact O-N 2.88Å; N257-N337 PolarHBondContact ND2-N 2.69Å; N257-Y338 HydrophobicContact CB-CD2 3.75Å; N257-Y338 HydrophobicContact CB-CE2 3.92Å
258A97.3Very high92.8Very high2 Ų257.4 Ų57.42%0.01730%0.303CS..Hα-helixtrans-66.3-45.3173.900000112L93 V216 V254 L255 L256 E260 L261 L262 Y338L93-A258 HydrophobicContact CD1-CB 4.15Å; L93-A258 HydrophobicContact CD2-CB 3.83Å; V216-A258 HydrophobicContact CG2-CB 4.39Å; V254-A258 WeakPolarHBondContact O-CB 3.34Å; V254-A258 PolarHBondContact O-N 3.42Å; V254-A258 VanDerWaalsContact O-N 3.14Å; L255-A258 PolarHBondContact O-N 2.81Å; L256-A258 PolarHBondContact O-N 3.42Å; A258-E260 VanDerWaalsContact C-N 3.33Å; A258-L261 PolarHBondContact O-N 2.98Å; A258-L262 VanDerWaalsContact O-CG 3.23Å; A258-L262 WeakPolarHBondContact O-CG 3.35Å; A258-L262 PolarHBondContact O-N 3.19Å; A258-L262 VanDerWaalsContact O-N 3.08Å; A258-Y338 HydrophobicContact CB-CE2 4.07Å
259L95.4Very high92.2Very high94 Ų9460.4 Ų60.449%0.49232%0.317SS..Hα-helixtrans-65.4-37.6177.6-68.6175.5000112.1L255 L256 L262L255-L259 WeakPolarHBondContact O-CG 3.49Å; L255-L259 PolarHBondContact O-N 2.8Å; L256-L259 PolarHBondContact O-N 3.3Å; L256-L259 VanDerWaalsContact O-N 3.15Å; L259-L262 HydrophobicContact CD2-CD1 4.43Å; L259-L262 PolarHBondContact O-N 3.42Å
260E94.8Very high91.7Very high84 Ų8464.6 Ų64.639%0.39333%0.332SS..Hα-helixtrans-61.6-48.5172.8-71.9175.4-179.300110.9L256 A258 L262 N263 H330L256-E260 WeakPolarHBondContact O-CG 3.33Å; L256-E260 PolarHBondContact O-N 3.41Å; A258-E260 VanDerWaalsContact C-N 3.33Å; E260-L262 VanDerWaalsContact C-N 3.28Å; E260-L262 PolarHBondContact O-N 2.96Å; E260-N263 PolarHBondContact O-N 3.26Å; E260-H330 PolarHBondContact O-CE1 3.11Å; E260-H330 VanDerWaalsContact O-CE1 3.3Å
261L94.5Very high91Very high5 Ų570.5 Ų70.53%0.02635%0.354CS..Hα-helixtrans-58.1-36.3176.9-86.5175.6000113.9L93 F103 N257 A258 N263 E331 H334 L335 Y338L93-L261 HydrophobicContact CD2-CB 4.28Å; L93-L261 HydrophobicContact CD2-CD1 3.79Å; F103-L261 HydrophobicContact CD1-CD1 4.08Å; F103-L261 HydrophobicContact CE1-CD1 4.45Å; F103-L261 HydrophobicContact CE1-CD2 4.41Å; F103-L261 HydrophobicContact CG-CD1 4.3Å; N257-L261 WeakPolarHBondContact O-CB 3.48Å; N257-L261 WeakPolarHBondContact O-CG 3.42Å; N257-L261 PolarHBondContact O-N 2.88Å; A258-L261 PolarHBondContact O-N 2.98Å; L261-N263 PolarHBondContact O-N 2.93Å; L261-E331 HydrophobicContact CD2-CB 4.17Å; L261-E331 HydrophobicContact CD2-CG 4.29Å; L261-H334 WeakPolarHBondContact CD2-O 3.44Å; L261-H334 WeakPolarHBondContact CG-O 3.43Å; L261-L335 HydrophobicContact CD2-CD2 4.25Å; L261-Y338 HydrophobicContact CD1-CD2 3.74Å; L261-Y338 HydrophobicContact CD1-CG 3.9Å
262L92.1Very high90.1Very high40 Ų4073.6 Ų73.621%0.20937%0.371CS..Hα-helixtrans-70.4-16.2179.3-67.5166.9000113.3T95 F214 A258 L259 E260 I264T95-L262 HydrophobicContact CG2-CD2 3.98Å; F214-L262 HydrophobicContact CB-CD1 4.25Å; F214-L262 HydrophobicContact CB-CD2 3.6Å; F214-L262 HydrophobicContact CD1-CD1 3.5Å; F214-L262 HydrophobicContact CD1-CD2 4.06Å; F214-L262 HydrophobicContact CD1-CG 4.44Å; F214-L262 HydrophobicContact CD2-CD1 3.57Å; F214-L262 HydrophobicContact CD2-CD2 4.44Å; F214-L262 HydrophobicContact CE1-CD1 3.59Å; F214-L262 HydrophobicContact CE2-CD1 3.65Å; F214-L262 HydrophobicContact CG-CD1 3.49Å; F214-L262 VanDerWaalsContact CG-CD1 3.49Å; F214-L262 HydrophobicContact CG-CD2 3.79Å; F214-L262 HydrophobicContact CG-CG 4.28Å; F214-L262 HydrophobicContact CZ-CD1 3.66Å; A258-L262 VanDerWaalsContact O-CG 3.23Å; A258-L262 WeakPolarHBondContact O-CG 3.35Å; A258-L262 PolarHBondContact O-N 3.19Å; A258-L262 VanDerWaalsContact O-N 3.08Å; L259-L262 HydrophobicContact CD2-CD1 4.43Å; L259-L262 PolarHBondContact O-N 3.42Å; E260-L262 VanDerWaalsContact C-N 3.28Å; E260-L262 PolarHBondContact O-N 2.96Å; L262-I264 VanDerWaalsContact C-N 3.26Å; L262-I264 HydrophobicContact CB-CD1 4.09Å; L262-I264 HydrophobicContact CB-CG1 3.83Å; L262-I264 HydrophobicContact CD1-CD1 4.26Å; L262-I264 PolarHBondContact O-N 3.02Å
263N90.9Very high89.4Confident53 Ų5372.6 Ų72.628%0.28337%0.37SS..THydrogen-bonded Turntrans52.341.8175.6-1659.1000113.4E260 L261 R265 H330E260-N263 PolarHBondContact O-N 3.26Å; L261-N263 PolarHBondContact O-N 2.93Å; N263-R265 PolarHBondContact ND2-NH2 2.87Å; N263-R265 VanDerWaalsContact ND2-NH2 3.11Å; N263-R265 PolarHBondContact O-N 3.2Å; N263-R265 PolarHBondContact OD1-NE 3.42Å; N263-R265 PolarHBondContact OD1-NH2 2.82Å; N263-H330 WeakPolarHBondContact CB-CE1 3.49Å; N263-H330 VanDerWaalsContact CG-CD2 3.47Å; N263-H330 PolarHBondContact ND2-CD2 3.44Å; N263-H330 PolarHBondContact ND2-NE2 3.42Å; N263-H330 PolarHBondContact OD1-NE2 3.31Å
264I87.8Confident88.7Confident114 Ų11474.7 Ų74.759%0.58539%0.386SS*.  trans-73.8117.1-176.4-56.2173.8000109.1L262L262-I264 VanDerWaalsContact C-N 3.26Å; L262-I264 HydrophobicContact CB-CD1 4.09Å; L262-I264 HydrophobicContact CB-CG1 3.83Å; L262-I264 HydrophobicContact CD1-CD1 4.26Å; L262-I264 PolarHBondContact O-N 3.02Å
265R85.9Confident87.8Confident132 Ų13278.3 Ų78.350%0.49840%0.403SS..  trans-111.2144.2-177.2-63172.5-172.9-167.4-2.8111N263 S267 D268N263-R265 PolarHBondContact ND2-NH2 2.87Å; N263-R265 VanDerWaalsContact ND2-NH2 3.11Å; N263-R265 PolarHBondContact O-N 3.2Å; N263-R265 PolarHBondContact OD1-NE 3.42Å; N263-R265 PolarHBondContact OD1-NH2 2.82Å; R265-S267 WeakPolarHBondContact CB-OG 3.42Å; R265-S267 PolarHBondContact O-N 3.24Å; R265-S267 VanDerWaalsContact O-N 3.09Å; R265-D268 PolarHBondContact N-OD2 2.86Å; R265-D268 VanDerWaalsContact O-CB 3.25Å; R265-D268 WeakPolarHBondContact O-CB 3.43Å; R265-D268 VanDerWaalsContact O-CG 3.29Å; R265-D268 PolarHBondContact O-N 3.18Å
266A81.8Confident86.9Confident104 Ų10480.4 Ų80.486%0.8641%0.411SS*.THydrogen-bonded Turntrans-58.1-27.4173.500000112.9D268A266-D268 PolarHBondContact O-N 3.31Å
267S82.6Confident86.2Confident65 Ų6583.5 Ų83.546%0.45542%0.421SS..THydrogen-bonded Turntrans-68.6-18.5175.553.60000114.1R265 K269 K270 R271R265-S267 WeakPolarHBondContact CB-OG 3.42Å; R265-S267 PolarHBondContact O-N 3.24Å; R265-S267 VanDerWaalsContact O-N 3.09Å; S267-K269 VanDerWaalsContact C-N 3.29Å; S267-K269 PolarHBondContact O-N 3.35Å; S267-K270 PolarHBondContact O-N 3.14Å; S267-K270 VanDerWaalsContact O-N 3.1Å; S267-R271 PolarHBondContact O-N 2.94Å
268D82.3Confident85.4Confident26 Ų2684.2 Ų84.214%0.13943%0.43CS..Hα-helixtrans-62.4-37.4-173.1-68.8-27.2000112.1R265 A266 K270 R271 N272R265-D268 PolarHBondContact N-OD2 2.86Å; R265-D268 VanDerWaalsContact O-CB 3.25Å; R265-D268 WeakPolarHBondContact O-CB 3.43Å; R265-D268 VanDerWaalsContact O-CG 3.29Å; R265-D268 PolarHBondContact O-N 3.18Å; A266-D268 PolarHBondContact O-N 3.31Å; D268-K270 VanDerWaalsContact C-N 3.35Å; D268-K270 PolarHBondContact O-N 2.9Å; D268-R271 PolarHBondContact O-N 3.5Å; D268-R271 IonicContact OD1-CZ 3.65Å; D268-R271 IonicContact OD1-NE 3.89Å; D268-R271 IonicContact OD1-NH2 3.08Å; D268-R271 PolarHBondContact OD1-NH2 2.92Å; D268-N272 WeakPolarHBondContact O-CB 3.26Å; D268-N272 PolarHBondContact O-N 3.48Å; D268-N272 PolarHBondContact O-ND2 2.99Å; D268-N272 PolarHBondContact O-OD1 3.46Å
269K81.4Confident84.5Confident160 Ų16085.7 Ų85.770%0.69644%0.437SS*.Hα-helixtrans-58-46.6174.7-175.3176.1-178.51770112S267 L273S267-K269 VanDerWaalsContact C-N 3.29Å; S267-K269 PolarHBondContact O-N 3.35Å; K269-L273 HydrophobicContact CG-CD1 4.19Å; K269-L273 WeakPolarHBondContact O-CB 3.41Å; K269-L273 VanDerWaalsContact O-CG 3.28Å; K269-L273 WeakPolarHBondContact O-CG 3.41Å; K269-L273 PolarHBondContact O-N 3.29Å; K269-L273 VanDerWaalsContact O-N 3.11Å
270K82.8Confident83.7Confident169 Ų16983.3 Ų83.374%0.73543%0.43SS*.Hα-helixtrans-68.1-41.1179.9-69.3-177.4179.5178.20111.1S267 D268 A274S267-K270 PolarHBondContact O-N 3.14Å; S267-K270 VanDerWaalsContact O-N 3.1Å; D268-K270 VanDerWaalsContact C-N 3.35Å; D268-K270 PolarHBondContact O-N 2.9Å; K270-A274 WeakPolarHBondContact O-CB 3.32Å; K270-A274 PolarHBondContact O-N 2.82Å
271R80.6Confident83Confident129 Ų12985.1 Ų85.149%0.48744%0.439SS..Hα-helixtrans-62-47.2177.5-177.3171.161.5151.70.9111.7S267 D268 A274 Q275S267-R271 PolarHBondContact O-N 2.94Å; D268-R271 PolarHBondContact O-N 3.5Å; D268-R271 IonicContact OD1-CZ 3.65Å; D268-R271 IonicContact OD1-NE 3.89Å; D268-R271 IonicContact OD1-NH2 3.08Å; D268-R271 PolarHBondContact OD1-NH2 2.92Å; R271-A274 PolarHBondContact O-N 2.96Å; R271-Q275 WeakPolarHBondContact O-CB 3.38Å; R271-Q275 PolarHBondContact O-N 3.44Å
272N78.9Confident82.1Confident78 Ų7893.7 Ų93.742%0.41747%0.471SS..Hα-helixtrans-63.4-45.7179.2-68.1-11.8000111.4D268 A274 Q275 E276D268-N272 WeakPolarHBondContact O-CB 3.26Å; D268-N272 PolarHBondContact O-N 3.48Å; D268-N272 PolarHBondContact O-ND2 2.99Å; D268-N272 PolarHBondContact O-OD1 3.46Å; N272-A274 VanDerWaalsContact C-N 3.33Å; N272-A274 PolarHBondContact O-N 3.02Å; N272-Q275 PolarHBondContact O-N 3.33Å; N272-E276 WeakPolarHBondContact O-CG 3.49Å; N272-E276 PolarHBondContact O-N 3.27Å
273L81.7Confident81.3Confident84 Ų8499.7 Ų99.744%0.4449%0.491SS..Hα-helixtrans-62.4-38.8176.1-72.6169.7000112.7K269 K277K269-L273 HydrophobicContact CG-CD1 4.19Å; K269-L273 WeakPolarHBondContact O-CB 3.41Å; K269-L273 VanDerWaalsContact O-CG 3.28Å; K269-L273 WeakPolarHBondContact O-CG 3.41Å; K269-L273 PolarHBondContact O-N 3.29Å; K269-L273 VanDerWaalsContact O-N 3.11Å; L273-K277 WeakPolarHBondContact O-CB 3.46Å; L273-K277 VanDerWaalsContact O-CG 3.27Å; L273-K277 WeakPolarHBondContact O-CG 3.47Å; L273-K277 PolarHBondContact O-N 3.08Å
274A82.2Confident80.6Confident57 Ų57103.4 Ų103.447%0.47151%0.51SS..Hα-helixtrans-66.4-4017600000111.4K270 R271 N272 K277 A278K270-A274 WeakPolarHBondContact O-CB 3.32Å; K270-A274 PolarHBondContact O-N 2.82Å; R271-A274 PolarHBondContact O-N 2.96Å; N272-A274 VanDerWaalsContact C-N 3.33Å; N272-A274 PolarHBondContact O-N 3.02Å; A274-K277 PolarHBondContact O-N 3.4Å; A274-A278 WeakPolarHBondContact O-CB 3.5Å; A274-A278 PolarHBondContact O-N 2.98Å
275Q78.1Confident79.7Confident76 Ų76106.7 Ų106.736%0.35552%0.516SS..Hα-helixtrans-66.4-45.9176.6-174.9175.1-16.100111.7R271 N272 K277 A278 E279R271-Q275 WeakPolarHBondContact O-CB 3.38Å; R271-Q275 PolarHBondContact O-N 3.44Å; N272-Q275 PolarHBondContact O-N 3.33Å; Q275-K277 VanDerWaalsContact C-N 3.32Å; Q275-K277 PolarHBondContact O-N 3.1Å; Q275-A278 PolarHBondContact O-N 3.49Å; Q275-E279 WeakPolarHBondContact CG-OE1 3.33Å; Q275-E279 PolarHBondContact NE2-OE1 3.29Å; Q275-E279 WeakPolarHBondContact O-CB 3.49Å; Q275-E279 WeakPolarHBondContact O-CG 3.42Å; Q275-E279 PolarHBondContact O-N 3.39Å
276E79.1Confident78.3Confident113 Ų113102.4 Ų102.453%0.52851%0.514SS..Hα-helixtrans-59.1-42.8175-74.7176.8175.300111.7N272 E279 A280N272-E276 WeakPolarHBondContact O-CG 3.49Å; N272-E276 PolarHBondContact O-N 3.27Å; E276-E279 PolarHBondContact O-N 3.39Å; E276-A280 VanDerWaalsContact O-CB 3.3Å; E276-A280 WeakPolarHBondContact O-CB 3.37Å; E276-A280 PolarHBondContact O-N 2.73Å
277K83.5Confident76.9Confident146 Ų146105.8 Ų105.864%0.63551%0.511SS*.Hα-helixtrans-62.3-45174.3-76.7177.8-179-173.70112L273 A274 Q275 E279 A280 Q281L273-K277 WeakPolarHBondContact O-CB 3.46Å; L273-K277 VanDerWaalsContact O-CG 3.27Å; L273-K277 WeakPolarHBondContact O-CG 3.47Å; L273-K277 PolarHBondContact O-N 3.08Å; A274-K277 PolarHBondContact O-N 3.4Å; Q275-K277 VanDerWaalsContact C-N 3.32Å; Q275-K277 PolarHBondContact O-N 3.1Å; K277-E279 VanDerWaalsContact C-N 3.35Å; K277-A280 PolarHBondContact O-N 3.31Å; K277-Q281 WeakPolarHBondContact O-CB 3.4Å; K277-Q281 WeakPolarHBondContact O-CG 3.19Å; K277-Q281 PolarHBondContact O-N 2.83Å
278A79.9Confident75.2Confident37 Ų37106 Ų10631%0.30652%0.523SS..Hα-helixtrans-64.1-40178.200000111.7A274 Q275 Q281 R282A274-A278 WeakPolarHBondContact O-CB 3.5Å; A274-A278 PolarHBondContact O-N 2.98Å; Q275-A278 PolarHBondContact O-N 3.49Å; A278-Q281 PolarHBondContact O-N 3.11Å; A278-R282 WeakPolarHBondContact O-CG 3.44Å; A278-R282 PolarHBondContact O-N 3.29Å
279E77.3Confident73.6Confident34 Ų34114 Ų11416%0.15956%0.557CS.*Hα-helixtrans-68.7-41.9176-75.1176.7-157.300112.1P206 Q275 E276 K277 Q281 R282 R283P206-E279 WeakPolarHBondContact CG-OE1 3.39Å; Q275-E279 WeakPolarHBondContact CG-OE1 3.33Å; Q275-E279 PolarHBondContact NE2-OE1 3.29Å; Q275-E279 WeakPolarHBondContact O-CB 3.49Å; Q275-E279 WeakPolarHBondContact O-CG 3.42Å; Q275-E279 PolarHBondContact O-N 3.39Å; E276-E279 PolarHBondContact O-N 3.39Å; K277-E279 VanDerWaalsContact C-N 3.35Å; E279-Q281 VanDerWaalsContact C-N 3.32Å; E279-Q281 PolarHBondContact O-N 3.48Å; E279-R282 PolarHBondContact O-N 3.39Å; E279-R283 WeakPolarHBondContact O-CG 3.48Å; E279-R283 PolarHBondContact O-N 2.98Å; E279-R283 IonicContact OE2-NH2 2.91Å
280A79.4Confident72.1Confident44 Ų44112.4 Ų112.436%0.36455%0.553SS.*Hα-helixtrans-60.2-43.6173.300000111.2E276 K277 R283 L284E276-A280 VanDerWaalsContact O-CB 3.3Å; E276-A280 WeakPolarHBondContact O-CB 3.37Å; E276-A280 PolarHBondContact O-N 2.73Å; K277-A280 PolarHBondContact O-N 3.31Å; A280-R283 PolarHBondContact O-N 3.43Å; A280-L284 WeakPolarHBondContact O-CB 3.49Å; A280-L284 WeakPolarHBondContact O-CD1 3.48Å; A280-L284 WeakPolarHBondContact O-CG 3.34Å; A280-L284 PolarHBondContact O-N 3.36Å
281Q79.5Confident70.6Confident122 Ų122114.2 Ų114.257%0.5756%0.556SS**Hα-helixtrans-62.8-41.5173.4-76178.4-19.600112.1K277 A278 E279 R283 L284 Y285K277-Q281 WeakPolarHBondContact O-CB 3.4Å; K277-Q281 WeakPolarHBondContact O-CG 3.19Å; K277-Q281 PolarHBondContact O-N 2.83Å; A278-Q281 PolarHBondContact O-N 3.11Å; E279-Q281 VanDerWaalsContact C-N 3.32Å; E279-Q281 PolarHBondContact O-N 3.48Å; Q281-R283 VanDerWaalsContact C-N 3.34Å; Q281-R283 PolarHBondContact O-N 2.7Å; Q281-L284 PolarHBondContact O-N 2.81Å; Q281-Y285 HydrophobicContact CB-CD2 4.38Å; Q281-Y285 WeakPolarHBondContact O-CB 3.5Å; Q281-Y285 WeakPolarHBondContact O-CD2 3.13Å; Q281-Y285 PolarHBondContact O-N 3.23Å
282R75.7Confident69.3Low185 Ų185117 Ų11770%0.69857%0.572SS**Hα-helixtrans-62.9-38.1173.2-75.6-176.8-158.9173.15.7112.4A278 E279 G286A278-R282 WeakPolarHBondContact O-CG 3.44Å; A278-R282 PolarHBondContact O-N 3.29Å; E279-R282 PolarHBondContact O-N 3.39Å; R282-G286 WeakPolarHBondContact O-CA 3.19Å; R282-G286 PolarHBondContact O-N 3.36Å
283R75.1Confident68.2Low165 Ų165117.5 Ų117.562%0.62357%0.573SS**Hα-helixtrans-67.1-39.1176.3-70.8174.1-168.8168.94.7111.7G204 E279 A280 Q281G204-R283 PolarHBondContact O-NH2 2.8Å; E279-R283 WeakPolarHBondContact O-CG 3.48Å; E279-R283 PolarHBondContact O-N 2.98Å; E279-R283 IonicContact OE2-NH2 2.91Å; A280-R283 PolarHBondContact O-N 3.43Å; Q281-R283 VanDerWaalsContact C-N 3.34Å; Q281-R283 PolarHBondContact O-N 2.7Å
284L76.2Confident67.1Low132 Ų132117 Ų11769%0.69158%0.577SS**Hα-helixtrans-76.1-42.9-179.3-74.1161.4000113.1A280 Q281A280-L284 WeakPolarHBondContact O-CB 3.49Å; A280-L284 WeakPolarHBondContact O-CD1 3.48Å; A280-L284 WeakPolarHBondContact O-CG 3.34Å; A280-L284 PolarHBondContact O-N 3.36Å; Q281-L284 PolarHBondContact O-N 2.81Å
285Y70.3Confident65.9Low182 Ų182119.9 Ų119.971%0.71460%0.601SS**Hα-helixtrans-112.2-16.6-170.8-60.5-74.7000114.3Q281 H287 G288Q281-Y285 HydrophobicContact CB-CD2 4.38Å; Q281-Y285 WeakPolarHBondContact O-CB 3.5Å; Q281-Y285 WeakPolarHBondContact O-CD2 3.13Å; Q281-Y285 PolarHBondContact O-N 3.23Å; Y285-H287 VanDerWaalsContact C-N 3.26Å; Y285-H287 PolarHBondContact O-N 3.2Å; Y285-G288 PolarHBondContact O-N 2.97Å; Y285-G288 VanDerWaalsContact O-N 3.13Å
286G57Low65.1Low43 Ų43120.5 Ų120.544%0.44362%0.619SS.*G310 helixtrans-73.5-10.1-175.200000115.2R282 G288R282-G286 WeakPolarHBondContact O-CA 3.19Å; R282-G286 PolarHBondContact O-N 3.36Å; G286-G288 PolarHBondContact O-N 2.66Å
287H51Low64.5Low175 Ų175115.9 Ų115.981%0.8160%0.599SS**G310 helixtrans-75.4-9.3168.5-101.149.9000113.4Y285Y285-H287 VanDerWaalsContact C-N 3.26Å; Y285-H287 PolarHBondContact O-N 3.2Å
288G47.7Very low64.2Low68 Ų68112.7 Ų112.770%0.70159%0.592SS**G310 helixtrans-86.1-9.8-173.600000116.6Y285 G286Y285-G288 PolarHBondContact O-N 2.97Å; Y285-G288 VanDerWaalsContact O-N 3.13Å; G286-G288 PolarHBondContact O-N 2.66Å
289F48.9Very low63.9Low196 Ų196116.7 Ų116.786%0.8661%0.608SS**SBendtrans-113.3-16-172.2-141.5-95.1000115.3R291F289-R291 PolarHBondContact O-N 3.45Å
290M49.6Very low63.6Low125 Ų125123.4 Ų123.462%0.61663%0.632SS**SBendtrans-91.691.1168.6-79.5-161.7-70.300109.3K292 H305M290-K292 PolarHBondContact O-N 3.14Å; M290-H305 VanDerWaalsContact SD-CE1 3.59Å
291R51.6Low63.4Low208 Ų208124.8 Ų124.879%0.78563%0.631SS**  trans-53.8106.7168.5-165.1174.4170.3-164.3-6.1107.4F289 L293F289-R291 PolarHBondContact O-N 3.45Å; R291-L293 PolarHBondContact O-N 3.18Å; R291-L293 VanDerWaalsContact O-N 3.09Å
292K53.2Low63.3Low188 Ų188123.4 Ų123.482%0.81762%0.623SS**PPolyproline II helixtrans-50.2121178.5-82.3-178.6178.2177.10108.2M290 S294M290-K292 PolarHBondContact O-N 3.14Å; K292-S294 PolarHBondContact O-N 2.98Å; K292-S294 VanDerWaalsContact O-N 3.11Å
293L56.1Low63.5Low87 Ų87120.1 Ų120.146%0.45562%0.616SS.*PPolyproline II helixtrans-53.5118.1174.3-76.8155.2000108.2R291 K302 H305R291-L293 PolarHBondContact O-N 3.18Å; R291-L293 VanDerWaalsContact O-N 3.09Å; L293-K302 HydrophobicContact CD2-CG 4.08Å; L293-H305 HydrophobicContact CD1-CB 4.4Å
294S57.2Low63.7Low75 Ų75119 Ų11952%0.52461%0.611SS.*PPolyproline II helixtrans-82.7159.5169.178.60000108.9K292 A296 S297K292-S294 PolarHBondContact O-N 2.98Å; K292-S294 VanDerWaalsContact O-N 3.11Å; S294-A296 PolarHBondContact O-N 3.24Å; S294-A296 PolarHBondContact OG-N 3.17Å; S294-S297 PolarHBondContact N-OG 2.94Å; S294-S297 WeakPolarHBondContact O-CB 3.27Å; S294-S297 PolarHBondContact O-N 3.07Å; S294-S297 PolarHBondContact O-OG 3.39Å
295A58.5Low63.8Low117 Ų117114.9 Ų114.997%0.96759%0.588SS**THydrogen-bonded Turntrans-58.5-12.9174.800000113.7
296A60.3Low64.4Low88 Ų88110.1 Ų110.173%0.72758%0.578SS**THydrogen-bonded Turntrans-98.511177.200000114.1S294S294-A296 PolarHBondContact O-N 3.24Å; S294-A296 PolarHBondContact OG-N 3.17Å
297S67.6Low65.8Low16 Ų16113.3 Ų113.311%0.11259%0.585CS.*  trans-70.5133.2-179.6-49.50000110.9S294 E301 K302S294-S297 PolarHBondContact N-OG 2.94Å; S294-S297 WeakPolarHBondContact O-CB 3.27Å; S294-S297 PolarHBondContact O-N 3.07Å; S294-S297 PolarHBondContact O-OG 3.39Å; S297-E301 WeakPolarHBondContact CA-OE2 3.41Å; S297-K302 VanDerWaalsContact O-CE 3.28Å; S297-K302 WeakPolarHBondContact O-CE 3.44Å
298T75.3Confident67.4Low79 Ų79108.5 Ų108.549%0.48556%0.563SS.*  trans-65153.4178.455.40000111.5W300 E301 K302T298-W300 PolarHBondContact O-N 3.01Å; T298-E301 PolarHBondContact N-OE2 2.88Å; T298-E301 WeakPolarHBondContact O-CB 3.35Å; T298-E301 PolarHBondContact O-N 2.9Å; T298-E301 VanDerWaalsContact OG1-CD 3.22Å; T298-E301 VanDerWaalsContact OG1-CG 3.22Å; T298-E301 WeakPolarHBondContact OG1-CG 3.41Å; T298-E301 PolarHBondContact OG1-OE2 3.32Å; T298-K302 PolarHBondContact O-N 2.8Å; T298-K302 VanDerWaalsContact O-N 3.11Å
299D74.4Confident69Low121 Ų121112.5 Ų112.565%0.64756%0.557SS**Hα-helixtrans-61.5-29.7-179-73.3-22.2000112.7K302 Q303D299-K302 PolarHBondContact O-N 2.98Å; D299-K302 IonicContact OD1-NZ 2.69Å; D299-K302 PolarHBondContact OD1-NZ 2.88Å; D299-Q303 WeakPolarHBondContact O-CB 3.47Å; D299-Q303 PolarHBondContact O-N 2.95Å
300W71.2Confident70.7Confident176 Ų176109.4 Ų109.467%0.66754%0.539SS*.Hα-helixtrans-63.5-41.6170.4172.3-108.1000113.1T298 Q303 R304T298-W300 PolarHBondContact O-N 3.01Å; W300-Q303 PolarHBondContact O-N 3.47Å; W300-R304 WeakPolarHBondContact O-CB 3.31Å; W300-R304 PolarHBondContact O-N 2.93Å
301E75.6Confident72.5Confident73 Ų73110.1 Ų110.134%0.34154%0.535SS..Hα-helixtrans-66.3-38.8176.6-73.4167.4141.400111.5S297 T298 H305S297-E301 WeakPolarHBondContact CA-OE2 3.41Å; T298-E301 PolarHBondContact N-OE2 2.88Å; T298-E301 WeakPolarHBondContact O-CB 3.35Å; T298-E301 PolarHBondContact O-N 2.9Å; T298-E301 VanDerWaalsContact OG1-CD 3.22Å; T298-E301 VanDerWaalsContact OG1-CG 3.22Å; T298-E301 WeakPolarHBondContact OG1-CG 3.41Å; T298-E301 PolarHBondContact OG1-OE2 3.32Å; E301-H305 WeakPolarHBondContact O-CB 3.18Å; E301-H305 PolarHBondContact O-N 2.85Å
302K76.6Confident74Confident93 Ų93105.4 Ų105.440%0.40452%0.522SS..Hα-helixtrans-63.5-44.5173.4-63.5175.4-164.2153.70111.5L293 S297 T298 D299 H305 T306L293-K302 HydrophobicContact CD2-CG 4.08Å; S297-K302 VanDerWaalsContact O-CE 3.28Å; S297-K302 WeakPolarHBondContact O-CE 3.44Å; T298-K302 PolarHBondContact O-N 2.8Å; T298-K302 VanDerWaalsContact O-N 3.11Å; D299-K302 PolarHBondContact O-N 2.98Å; D299-K302 IonicContact OD1-NZ 2.69Å; D299-K302 PolarHBondContact OD1-NZ 2.88Å; K302-H305 PolarHBondContact O-N 3.5Å; K302-T306 WeakPolarHBondContact O-CB 3.42Å; K302-T306 PolarHBondContact O-N 2.82Å; K302-T306 PolarHBondContact O-OG1 3.37Å
303Q80.3Confident75.5Confident115 Ų11599.3 Ų99.354%0.53750%0.497SS..Hα-helixtrans-64.5-43.9178.5-170.4175.4-2.500111.3D299 W300 T306 L307D299-Q303 WeakPolarHBondContact O-CB 3.47Å; D299-Q303 PolarHBondContact O-N 2.95Å; W300-Q303 PolarHBondContact O-N 3.47Å; Q303-T306 PolarHBondContact O-N 3.19Å; Q303-L307 HydrophobicContact CG-CD1 4.4Å; Q303-L307 WeakPolarHBondContact O-CG 3.35Å; Q303-L307 PolarHBondContact O-N 3.03Å
304R79.8Confident77Confident141 Ų14199.3 Ų99.353%0.53250%0.497SS..Hα-helixtrans-60.7-47.3175.3-179.1177.7174148-0.3112.4W300 T306 L307 E308W300-R304 WeakPolarHBondContact O-CB 3.31Å; W300-R304 PolarHBondContact O-N 2.93Å; R304-T306 VanDerWaalsContact C-N 3.26Å; R304-T306 PolarHBondContact O-N 3.39Å; R304-L307 PolarHBondContact O-N 3.35Å; R304-E308 HydrophobicContact CG-CG 4.48Å; R304-E308 IonicContact CZ-OE1 3.28Å; R304-E308 IonicContact NE-OE1 2.89Å; R304-E308 PolarHBondContact NE-OE1 2.99Å; R304-E308 IonicContact NH2-OE1 2.88Å; R304-E308 PolarHBondContact NH2-OE1 3.11Å; R304-E308 WeakPolarHBondContact O-CB 3.43Å; R304-E308 WeakPolarHBondContact O-CG 3.48Å; R304-E308 PolarHBondContact O-N 3.34Å
305H77.8Confident78.4Confident46 Ų46101 Ų10121%0.21349%0.494CS..Hα-helixtrans-63.2-35178.7-165.1-65.7000111.9M290 L293 E301 K302 R309M290-H305 VanDerWaalsContact SD-CE1 3.59Å; L293-H305 HydrophobicContact CD1-CB 4.4Å; E301-H305 WeakPolarHBondContact O-CB 3.18Å; E301-H305 PolarHBondContact O-N 2.85Å; K302-H305 PolarHBondContact O-N 3.5Å; H305-R309 WeakPolarHBondContact O-CB 3.28Å; H305-R309 PolarHBondContact O-N 2.86Å
306T83.4Confident79.5Confident82 Ų82100.5 Ų100.550%0.50347%0.472SS..Hα-helixtrans-67.1-44.2175.2-55.10000111.4K302 Q303 R304 R309 R310K302-T306 WeakPolarHBondContact O-CB 3.42Å; K302-T306 PolarHBondContact O-N 2.82Å; K302-T306 PolarHBondContact O-OG1 3.37Å; Q303-T306 PolarHBondContact O-N 3.19Å; R304-T306 VanDerWaalsContact C-N 3.26Å; R304-T306 PolarHBondContact O-N 3.39Å; T306-R309 PolarHBondContact O-N 3.2Å; T306-R310 WeakPolarHBondContact O-CB 3.49Å; T306-R310 PolarHBondContact O-N 3.4Å
307L85.3Confident80.7Confident110 Ų110101.2 Ų101.258%0.57646%0.46SS*.Hα-helixtrans-65.1-41.1176.2-72171.1000112.3Q303 R304 R310 R311Q303-L307 HydrophobicContact CG-CD1 4.4Å; Q303-L307 WeakPolarHBondContact O-CG 3.35Å; Q303-L307 PolarHBondContact O-N 3.03Å; R304-L307 PolarHBondContact O-N 3.35Å; L307-R310 PolarHBondContact O-N 2.92Å; L307-R311 WeakPolarHBondContact O-CB 3.38Å; L307-R311 PolarHBondContact O-N 3.29Å
308E84.4Confident81.6Confident74 Ų74104.6 Ų104.635%0.34648%0.477SS..Hα-helixtrans-64.5-43.9176.7-76.6176.6-177.700111.5R304 R310 R311 E312R304-E308 HydrophobicContact CG-CG 4.48Å; R304-E308 IonicContact CZ-OE1 3.28Å; R304-E308 IonicContact NE-OE1 2.89Å; R304-E308 PolarHBondContact NE-OE1 2.99Å; R304-E308 IonicContact NH2-OE1 2.88Å; R304-E308 PolarHBondContact NH2-OE1 3.11Å; R304-E308 WeakPolarHBondContact O-CB 3.43Å; R304-E308 WeakPolarHBondContact O-CG 3.48Å; R304-E308 PolarHBondContact O-N 3.34Å; E308-R310 PolarHBondContact O-N 3.08Å; E308-R311 PolarHBondContact O-N 2.99Å; E308-E312 PolarHBondContact O-N 3.24Å
309R81.8Confident82.1Confident153 Ų153102.9 Ų102.958%0.57747%0.47SS*.Hα-helixtrans-59.7-46.5173.6-164.7-174.180.4-165-5.1111.2H305 T306 R311 E312 E313H305-R309 WeakPolarHBondContact O-CB 3.28Å; H305-R309 PolarHBondContact O-N 2.86Å; T306-R309 PolarHBondContact O-N 3.2Å; R309-R311 VanDerWaalsContact C-N 3.32Å; R309-R311 PolarHBondContact O-N 3.18Å; R309-E312 PolarHBondContact O-N 3.41Å; R309-E313 IonicContact CZ-OE1 3.89Å; R309-E313 IonicContact NE-OE1 3.54Å; R309-E313 PolarHBondContact NE-OE1 2.95Å; R309-E313 IonicContact NH2-OE1 2.94Å; R309-E313 WeakPolarHBondContact O-CG 3.49Å; R309-E313 PolarHBondContact O-N 3.04Å
310R85.4Confident82.5Confident131 Ų131101.3 Ų101.349%0.49446%0.459SS..Hα-helixtrans-63.5-37.8179.2-171.156.5172.6-179.91.1112.4T306 L307 E308 E312 E313 L314T306-R310 WeakPolarHBondContact O-CB 3.49Å; T306-R310 PolarHBondContact O-N 3.4Å; L307-R310 PolarHBondContact O-N 2.92Å; E308-R310 PolarHBondContact O-N 3.08Å; R310-E312 VanDerWaalsContact C-N 3.35Å; R310-E313 WeakPolarHBondContact CD-OE2 3.43Å; R310-E313 IonicContact CZ-OE2 2.95Å; R310-E313 IonicContact NH1-OE2 3.78Å; R310-E313 PolarHBondContact NH1-OE2 3.29Å; R310-L314 HydrophobicContact CG-CD1 4.23Å; R310-L314 WeakPolarHBondContact O-CB 3.41Å; R310-L314 VanDerWaalsContact O-CG 3.28Å; R310-L314 WeakPolarHBondContact O-CG 3.45Å; R310-L314 PolarHBondContact O-N 3.45Å
311R87.1Confident83.3Confident140 Ų14096.7 Ų96.753%0.52845%0.45SS..Hα-helixtrans-63.1-41.7174.9-171-175.275.8179.31.4111.4L307 E308 R309 K315L307-R311 WeakPolarHBondContact O-CB 3.38Å; L307-R311 PolarHBondContact O-N 3.29Å; E308-R311 PolarHBondContact O-N 2.99Å; R309-R311 VanDerWaalsContact C-N 3.32Å; R309-R311 PolarHBondContact O-N 3.18Å; R311-K315 WeakPolarHBondContact O-CG 3.49Å; R311-K315 PolarHBondContact O-N 3.41Å
312E83.1Confident83.8Confident109 Ų109101.2 Ų101.251%0.50946%0.464SS..Hα-helixtrans-68.5-44.4178.8-151.767.2-164.300111.4E308 R309 R310 L314 K315 E316E308-E312 PolarHBondContact O-N 3.24Å; R309-E312 PolarHBondContact O-N 3.41Å; R310-E312 VanDerWaalsContact C-N 3.35Å; E312-L314 PolarHBondContact O-N 3Å; E312-K315 PolarHBondContact O-N 3.42Å; E312-E316 PolarHBondContact O-N 3.29Å
313E84.3Confident84.2Confident60 Ų60101.9 Ų101.928%0.2846%0.464SS..Hα-helixtrans-54.7-48.4172.7-72167-162.800111.5R309 R310 K315 E316 Q317R309-E313 IonicContact CZ-OE1 3.89Å; R309-E313 IonicContact NE-OE1 3.54Å; R309-E313 PolarHBondContact NE-OE1 2.95Å; R309-E313 IonicContact NH2-OE1 2.94Å; R309-E313 WeakPolarHBondContact O-CG 3.49Å; R309-E313 PolarHBondContact O-N 3.04Å; R310-E313 WeakPolarHBondContact CD-OE2 3.43Å; R310-E313 IonicContact CZ-OE2 2.95Å; R310-E313 IonicContact NH1-OE2 3.78Å; R310-E313 PolarHBondContact NH1-OE2 3.29Å; E313-K315 PolarHBondContact O-N 3.08Å; E313-E316 PolarHBondContact O-N 3.22Å; E313-Q317 WeakPolarHBondContact O-CG 3.4Å; E313-Q317 PolarHBondContact O-N 3.02Å
314L87.3Confident84.4Confident87 Ų87100.8 Ų100.846%0.45546%0.459SS..Hα-helixtrans-66-36.8179.6-74.2171.3000112.6R310 E312 L318R310-L314 HydrophobicContact CG-CD1 4.23Å; R310-L314 WeakPolarHBondContact O-CB 3.41Å; R310-L314 VanDerWaalsContact O-CG 3.28Å; R310-L314 WeakPolarHBondContact O-CG 3.45Å; R310-L314 PolarHBondContact O-N 3.45Å; E312-L314 PolarHBondContact O-N 3Å; L314-L318 WeakPolarHBondContact O-CB 3.45Å; L314-L318 PolarHBondContact O-N 2.71Å
315K86.8Confident84.9Confident109 Ų10997.2 Ų97.247%0.47445%0.453SS..Hα-helixtrans-64-42.2174.6-79.8177.4179.3-178.30111.6R311 E312 E313 L318 A319R311-K315 WeakPolarHBondContact O-CG 3.49Å; R311-K315 PolarHBondContact O-N 3.41Å; E312-K315 PolarHBondContact O-N 3.42Å; E313-K315 PolarHBondContact O-N 3.08Å; K315-L318 PolarHBondContact O-N 3.04Å; K315-A319 WeakPolarHBondContact O-CB 3.25Å; K315-A319 PolarHBondContact O-N 3.03Å
316E82.9Confident85.4Confident107 Ų10798.5 Ų98.550%0.547%0.467SS..Hα-helixtrans-66.1-44.6177.9-173.4166.2-155.300111.3E312 E313 L318 A319 Q320E312-E316 PolarHBondContact O-N 3.29Å; E313-E316 PolarHBondContact O-N 3.22Å; E316-L318 PolarHBondContact O-N 3.37Å; E316-A319 PolarHBondContact O-N 3.43Å; E316-Q320 PolarHBondContact O-N 2.96Å
317Q84.5Confident85.7Confident103 Ų10397.2 Ų97.248%0.48145%0.453SS..Hα-helixtrans-58.6-46173.3-74.5-177.3-2100112.1E313 A319 Q320 V321E313-Q317 WeakPolarHBondContact O-CG 3.4Å; E313-Q317 PolarHBondContact O-N 3.02Å; Q317-A319 VanDerWaalsContact C-N 3.33Å; Q317-A319 PolarHBondContact O-N 3.39Å; Q317-Q320 WeakPolarHBondContact O-CB 3.4Å; Q317-Q320 PolarHBondContact O-N 3.06Å; Q317-V321 WeakPolarHBondContact O-CG2 3.45Å; Q317-V321 PolarHBondContact O-N 3.31Å
318L87.4Confident85.9Confident87 Ų8794.6 Ų94.646%0.45544%0.438SS..Hα-helixtrans-62.6-40.2177.6-178.463.2000111.9L314 K315 E316 Q320 V321 R322L314-L318 WeakPolarHBondContact O-CB 3.45Å; L314-L318 PolarHBondContact O-N 2.71Å; K315-L318 PolarHBondContact O-N 3.04Å; E316-L318 PolarHBondContact O-N 3.37Å; L318-Q320 VanDerWaalsContact C-N 3.34Å; L318-V321 PolarHBondContact O-N 3.38Å; L318-R322 WeakPolarHBondContact O-CB 3.4Å; L318-R322 VanDerWaalsContact O-CG 3.3Å; L318-R322 WeakPolarHBondContact O-CG 3.47Å; L318-R322 PolarHBondContact O-N 3.34Å
319A84.4Confident86.3Confident43 Ų4396.1 Ų96.136%0.35545%0.445SS..Hα-helixtrans-64.5-39.4175.500000111.8K315 E316 Q317 R323K315-A319 WeakPolarHBondContact O-CB 3.25Å; K315-A319 PolarHBondContact O-N 3.03Å; E316-A319 PolarHBondContact O-N 3.43Å; Q317-A319 VanDerWaalsContact C-N 3.33Å; Q317-A319 PolarHBondContact O-N 3.39Å; A319-R323 WeakPolarHBondContact O-CG 3.31Å; A319-R323 PolarHBondContact O-N 2.88Å; A319-R323 VanDerWaalsContact O-N 3.07Å
320Q83.6Confident86.8Confident89 Ų8990 Ų9042%0.41642%0.423SS..Hα-helixtrans-63.6-48.3175.1-173.5177.12.600111.8E316 Q317 L318 R322 R323 Q324E316-Q320 PolarHBondContact O-N 2.96Å; Q317-Q320 WeakPolarHBondContact O-CB 3.4Å; Q317-Q320 PolarHBondContact O-N 3.06Å; L318-Q320 VanDerWaalsContact C-N 3.34Å; Q320-R322 PolarHBondContact O-N 3.49Å; Q320-R323 PolarHBondContact O-N 3.43Å; Q320-Q324 PolarHBondContact O-N 2.91Å
321V86.9Confident87.2Confident79 Ų7984 Ų8448%0.47940%0.4SS..Hα-helixtrans-60-45.6177.61720000111Q317 L318 R323 Q324 V325Q317-V321 WeakPolarHBondContact O-CG2 3.45Å; Q317-V321 PolarHBondContact O-N 3.31Å; L318-V321 PolarHBondContact O-N 3.38Å; V321-R323 VanDerWaalsContact C-N 3.33Å; V321-R323 PolarHBondContact O-N 3.45Å; V321-Q324 PolarHBondContact O-N 3.2Å; V321-V325 HydrophobicContact CG1-CG2 4.26Å; V321-V325 WeakPolarHBondContact O-CG2 3.32Å; V321-V325 PolarHBondContact O-N 2.98Å
322R87.8Confident87.5Confident167 Ų16781.4 Ų81.463%0.6340%0.397SS*.Hα-helixtrans-60-41.3177.3-75.6175.2177.2-177.7-1.3112.8L318 Q320 S326L318-R322 WeakPolarHBondContact O-CB 3.4Å; L318-R322 VanDerWaalsContact O-CG 3.3Å; L318-R322 WeakPolarHBondContact O-CG 3.47Å; L318-R322 PolarHBondContact O-N 3.34Å; Q320-R322 PolarHBondContact O-N 3.49Å; R322-S326 WeakPolarHBondContact O-CB 3.27Å; R322-S326 PolarHBondContact O-N 3.47Å
323R83.9Confident88Confident108 Ų10883.3 Ų83.341%0.40841%0.406SS..Hα-helixtrans-63.9-43.3175.2-76.7-174.9-67.5-140.42.1111.4A319 Q320 V321 S326 R327A319-R323 WeakPolarHBondContact O-CG 3.31Å; A319-R323 PolarHBondContact O-N 2.88Å; A319-R323 VanDerWaalsContact O-N 3.07Å; Q320-R323 PolarHBondContact O-N 3.43Å; V321-R323 VanDerWaalsContact C-N 3.33Å; V321-R323 PolarHBondContact O-N 3.45Å; R323-S326 PolarHBondContact O-N 3.41Å; R323-R327 WeakPolarHBondContact O-CB 3.42Å; R323-R327 PolarHBondContact O-N 2.97Å
324Q85.1Confident88.5Confident92 Ų9283.7 Ų83.743%0.4341%0.408SS..Hα-helixtrans-63.1-47.6178.3-176.5175.3-700111.8Q320 V321 S326 R327 E328Q320-Q324 PolarHBondContact O-N 2.91Å; V321-Q324 PolarHBondContact O-N 3.2Å; Q324-S326 PolarHBondContact O-N 3.27Å; Q324-R327 WeakPolarHBondContact O-CB 3.42Å; Q324-R327 PolarHBondContact O-N 3.47Å; Q324-E328 WeakPolarHBondContact CG-OE1 3.24Å; Q324-E328 PolarHBondContact NE2-OE1 2.83Å; Q324-E328 WeakPolarHBondContact O-CB 3.45Å; Q324-E328 WeakPolarHBondContact O-CG 3.3Å; Q324-E328 PolarHBondContact O-N 3.41Å
325V88.8Confident88.7Confident65 Ų6581.6 Ų81.639%0.39440%0.396SS..Hα-helixtrans-60-48.7177.2172.20000110.6V321 R327 E328 E329V321-V325 HydrophobicContact CG1-CG2 4.26Å; V321-V325 WeakPolarHBondContact O-CG2 3.32Å; V321-V325 PolarHBondContact O-N 2.98Å; V325-R327 VanDerWaalsContact C-N 3.28Å; V325-R327 PolarHBondContact O-N 2.9Å; V325-E328 PolarHBondContact O-N 3.46Å; V325-E329 HydrophobicContact CG1-CG 4.31Å; V325-E329 WeakPolarHBondContact O-CB 3.48Å; V325-E329 WeakPolarHBondContact O-CG 3.37Å; V325-E329 PolarHBondContact O-N 2.92Å
326S89.3Confident89.1Confident73 Ų7379 Ų7951%0.5140%0.4SS..Hα-helixtrans-61.2-36.5178.5179.30000112.7R322 R323 Q324 H330R322-S326 WeakPolarHBondContact O-CB 3.27Å; R322-S326 PolarHBondContact O-N 3.47Å; R323-S326 PolarHBondContact O-N 3.41Å; Q324-S326 PolarHBondContact O-N 3.27Å; S326-H330 WeakPolarHBondContact O-CB 3.35Å; S326-H330 PolarHBondContact O-N 3.4Å; S326-H330 VanDerWaalsContact O-N 3.11Å
327R88.9Confident89.8Confident56 Ų5676.5 Ų76.521%0.21139%0.391CS..Hα-helixtrans-66.7-47.4174.3179.4179179.1165.19.3111.3T95 R101 R323 Q324 V325 H330 E331T95-R327 PolarHBondContact OG1-NH2 2.98Å; R101-R327 VanDerWaalsContact CD-CZ 3.41Å; R101-R327 VanDerWaalsContact CD-NH2 3.35Å; R323-R327 WeakPolarHBondContact O-CB 3.42Å; R323-R327 PolarHBondContact O-N 2.97Å; Q324-R327 WeakPolarHBondContact O-CB 3.42Å; Q324-R327 PolarHBondContact O-N 3.47Å; V325-R327 VanDerWaalsContact C-N 3.28Å; V325-R327 PolarHBondContact O-N 2.9Å; R327-H330 PolarHBondContact O-N 3.24Å; R327-E331 HydrophobicContact CG-CG 4.37Å; R327-E331 WeakPolarHBondContact CG-OE1 3.46Å; R327-E331 IonicContact CZ-OE1 3.42Å; R327-E331 IonicContact NE-OE1 3.51Å; R327-E331 PolarHBondContact NE-OE1 3.24Å; R327-E331 IonicContact NH2-OE1 2.73Å; R327-E331 WeakPolarHBondContact O-CB 3.05Å; R327-E331 VanDerWaalsContact O-CG 3.3Å; R327-E331 WeakPolarHBondContact O-CG 3.39Å; R327-E331 PolarHBondContact O-N 3.45Å
328E90.4Very high90.4Very high54 Ų5471.9 Ų71.925%0.25237%0.369SS..Hα-helixtrans-63.4-42.7179.6-76.7173.4-170.100111.9R101 Q324 V325 E331 N332R101-E328 IonicContact NH1-OE1 2.68Å; Q324-E328 WeakPolarHBondContact CG-OE1 3.24Å; Q324-E328 PolarHBondContact NE2-OE1 2.83Å; Q324-E328 WeakPolarHBondContact O-CB 3.45Å; Q324-E328 WeakPolarHBondContact O-CG 3.3Å; Q324-E328 PolarHBondContact O-N 3.41Å; V325-E328 PolarHBondContact O-N 3.46Å; E328-E331 PolarHBondContact O-N 2.94Å; E328-N332 WeakPolarHBondContact O-CB 3.37Å; E328-N332 PolarHBondContact O-N 2.82Å; E328-N332 PolarHBondContact O-ND2 3.03Å; E328-N332 PolarHBondContact O-OD1 3.18Å
329E92.6Very high90.8Very high107 Ų10772.1 Ų72.150%0.536%0.364SS..Hα-helixtrans-58.4-47.9173.6-75173.6169.600111.5V325 N332 Q333V325-E329 HydrophobicContact CG1-CG 4.31Å; V325-E329 WeakPolarHBondContact O-CB 3.48Å; V325-E329 WeakPolarHBondContact O-CG 3.37Å; V325-E329 PolarHBondContact O-N 2.92Å; E329-N332 PolarHBondContact O-N 3.23Å; E329-Q333 VanDerWaalsContact O-CG 3.31Å; E329-Q333 WeakPolarHBondContact O-CG 3.44Å; E329-Q333 PolarHBondContact O-N 3.24Å; E329-Q333 VanDerWaalsContact O-N 3.1Å
330H92.9Very high91.5Very high24 Ų2472.1 Ų72.111%0.11136%0.355CS..Hα-helixtrans-60.7-50.6177.5-179.9-79.9000111.4E260 N263 S326 R327 N332 Q333 H334E260-H330 PolarHBondContact O-CE1 3.11Å; E260-H330 VanDerWaalsContact O-CE1 3.3Å; N263-H330 WeakPolarHBondContact CB-CE1 3.49Å; N263-H330 VanDerWaalsContact CG-CD2 3.47Å; N263-H330 PolarHBondContact ND2-CD2 3.44Å; N263-H330 PolarHBondContact ND2-NE2 3.42Å; N263-H330 PolarHBondContact OD1-NE2 3.31Å; S326-H330 WeakPolarHBondContact O-CB 3.35Å; S326-H330 PolarHBondContact O-N 3.4Å; S326-H330 VanDerWaalsContact O-N 3.11Å; R327-H330 PolarHBondContact O-N 3.24Å; H330-N332 VanDerWaalsContact C-N 3.33Å; H330-N332 PolarHBondContact O-N 3.43Å; H330-Q333 PolarHBondContact O-N 2.97Å; H330-H334 AromaticContact CD2-CE1 3.66Å; H330-H334 AromaticContact CD2-ND1 3.53Å; H330-H334 AromaticContact CE1-CG 3.72Å; H330-H334 AromaticContact CE1-ND1 3.53Å; H330-H334 AromaticContact CG-ND1 3.85Å; H330-H334 AromaticContact ND1-ND1 3.86Å; H330-H334 AromaticContact NE2-CE1 3.59Å; H330-H334 AromaticContact NE2-CG 3.8Å; H330-H334 AromaticContact NE2-ND1 3.38Å; H330-H334 PolarHBondContact NE2-ND1 3.12Å; H330-H334 PolarHBondContact O-N 2.94Å; H330-H334 PolarHBondContact O-ND1 2.99Å
331E93.4Very high92.2Very high4 Ų468.4 Ų68.42%0.01934%0.337CS..Hα-helixtrans-58.6-46180-73.3174.2178.500110.7R101 F103 L261 R327 E328 Q333 H334 L335R101-E331 IonicContact CZ-OE1 3.28Å; R101-E331 IonicContact CZ-OE2 3.88Å; R101-E331 VanDerWaalsContact NE-CD 3.32Å; R101-E331 IonicContact NE-OE1 3.02Å; R101-E331 PolarHBondContact NE-OE1 2.87Å; R101-E331 IonicContact NE-OE2 3.99Å; R101-E331 PolarHBondContact NE-OE2 3.35Å; R101-E331 IonicContact NH2-OE2 2.98Å; R101-E331 PolarHBondContact NH2-OE2 3.47Å; F103-E331 HydrophobicContact CZ-CG 4.29Å; F103-E331 WeakPolarHBondContact CZ-OE2 3.45Å; L261-E331 HydrophobicContact CD2-CB 4.17Å; L261-E331 HydrophobicContact CD2-CG 4.29Å; R327-E331 HydrophobicContact CG-CG 4.37Å; R327-E331 WeakPolarHBondContact CG-OE1 3.46Å; R327-E331 IonicContact CZ-OE1 3.42Å; R327-E331 IonicContact NE-OE1 3.51Å; R327-E331 PolarHBondContact NE-OE1 3.24Å; R327-E331 IonicContact NH2-OE1 2.73Å; R327-E331 WeakPolarHBondContact O-CB 3.05Å; R327-E331 VanDerWaalsContact O-CG 3.3Å; R327-E331 WeakPolarHBondContact O-CG 3.39Å; R327-E331 PolarHBondContact O-N 3.45Å; E328-E331 PolarHBondContact O-N 2.94Å; E331-Q333 VanDerWaalsContact C-N 3.27Å; E331-Q333 PolarHBondContact O-N 2.97Å; E331-H334 CarbonylContact O-C 3.57Å; E331-H334 PolarHBondContact O-N 3.32Å; E331-L335 VanDerWaalsContact O-CG 3.29Å; E331-L335 WeakPolarHBondContact O-CG 3.32Å; E331-L335 PolarHBondContact O-N 2.97Å; E331-L335 VanDerWaalsContact O-N 3.11Å
332N92.5Very high92.7Very high87 Ų8765.5 Ų65.547%0.46532%0.318SS..Hα-helixtrans-61.5-32.2179.1-67.5-18000112.9E328 E329 H330 R340E328-N332 WeakPolarHBondContact O-CB 3.37Å; E328-N332 PolarHBondContact O-N 2.82Å; E328-N332 PolarHBondContact O-ND2 3.03Å; E328-N332 PolarHBondContact O-OD1 3.18Å; E329-N332 PolarHBondContact O-N 3.23Å; H330-N332 VanDerWaalsContact C-N 3.33Å; H330-N332 PolarHBondContact O-N 3.43Å; N332-R340 PolarHBondContact OD1-NH1 3.4Å
333Q94.1Very high93.1Very high148 Ų14859.1 Ų59.169%0.69230%0.298SS*.Hα-helixtrans-80.2-25.5178.1-71.517212.600113.4E329 H330 E331E329-Q333 VanDerWaalsContact O-CG 3.31Å; E329-Q333 WeakPolarHBondContact O-CG 3.44Å; E329-Q333 PolarHBondContact O-N 3.24Å; E329-Q333 VanDerWaalsContact O-N 3.1Å; H330-Q333 PolarHBondContact O-N 2.97Å; E331-Q333 VanDerWaalsContact C-N 3.27Å; E331-Q333 PolarHBondContact O-N 2.97Å
334H94.4Very high93.7Very high69 Ų6954.9 Ų54.932%0.31928%0.284SS..SBendtrans-119.725.4-171.1-56.384.4000112.7L261 H330 E331 G336L261-H334 WeakPolarHBondContact CD2-O 3.44Å; L261-H334 WeakPolarHBondContact CG-O 3.43Å; H330-H334 AromaticContact CD2-CE1 3.66Å; H330-H334 AromaticContact CD2-ND1 3.53Å; H330-H334 AromaticContact CE1-CG 3.72Å; H330-H334 AromaticContact CE1-ND1 3.53Å; H330-H334 AromaticContact CG-ND1 3.85Å; H330-H334 AromaticContact ND1-ND1 3.86Å; H330-H334 AromaticContact NE2-CE1 3.59Å; H330-H334 AromaticContact NE2-CG 3.8Å; H330-H334 AromaticContact NE2-ND1 3.38Å; H330-H334 PolarHBondContact NE2-ND1 3.12Å; H330-H334 PolarHBondContact O-N 2.94Å; H330-H334 PolarHBondContact O-ND1 2.99Å; E331-H334 CarbonylContact O-C 3.57Å; E331-H334 PolarHBondContact O-N 3.32Å; H334-G336 PolarHBondContact O-N 3.43Å
335L92.8Very high94Very high42 Ų4257.1 Ų57.122%0.2230%0.299CS..  trans-58.4-32.1176.4-79.7173.1000112.4F103 L261 E331 N337 Y338F103-L335 HydrophobicContact CD1-CD2 3.78Å; F103-L335 HydrophobicContact CE1-CD2 3.79Å; L261-L335 HydrophobicContact CD2-CD2 4.25Å; E331-L335 VanDerWaalsContact O-CG 3.29Å; E331-L335 WeakPolarHBondContact O-CG 3.32Å; E331-L335 PolarHBondContact O-N 2.97Å; E331-L335 VanDerWaalsContact O-N 3.11Å; L335-N337 PolarHBondContact O-N 3.24Å; L335-Y338 VanDerWaalsContact O-CB 3.29Å; L335-Y338 WeakPolarHBondContact O-CB 3.45Å; L335-Y338 PolarHBondContact O-N 3.3Å
336G94.9Very high94.3Very high54 Ų5458.1 Ų58.156%0.55730%0.302SS*.THydrogen-bonded Turntrans55.1-122.7-170.800000109.9H334H334-G336 PolarHBondContact O-N 3.43Å
337N96.3Very high94.6Very high56 Ų5662.5 Ų62.530%0.29931%0.312SS..THydrogen-bonded Turntrans-96.512.4174.6-158.527.3000114.1Y105 N106 N257 L335Y105-N337 HydrophobicContact CD2-CB 4.37Å; Y105-N337 HydrophobicContact CE2-CB 3.67Å; N106-N337 WeakPolarHBondContact CB-OD1 3.35Å; N106-N337 PolarHBondContact N-O 3.44Å; N106-N337 PolarHBondContact ND2-O 3.46Å; N257-N337 PolarHBondContact ND2-N 2.69Å; L335-N337 PolarHBondContact O-N 3.24Å
338Y98.1Very high94.9Very high5 Ų565.9 Ų65.92%0.0233%0.334CS..EExtended strand (participates in β ladder)trans-83.3156.9167.4-79.4-80.2000111.5L93 F103 L104 Y105 V254 N257 A258 L261 L335L93-Y338 HydrophobicContact CB-CD1 4.27Å; L93-Y338 HydrophobicContact CB-CE1 3.55Å; L93-Y338 HydrophobicContact CD2-CE1 4.49Å; L93-Y338 HydrophobicContact CD2-CE2 4.31Å; F103-Y338 HydrophobicContact CB-CD1 3.67Å; F103-Y338 HydrophobicContact CB-CE1 4.38Å; F103-Y338 HydrophobicContact CB-CG 4.19Å; L104-Y338 CarbonylContact O-C 3.51Å; L104-Y338 WeakPolarHBondContact O-CA 3.38Å; Y105-Y338 AromaticContact CD2-CD1 3.94Å; Y105-Y338 HydrophobicContact CD2-CD1 3.94Å; Y105-Y338 AromaticContact CD2-CD2 3.69Å; Y105-Y338 HydrophobicContact CD2-CD2 3.69Å; Y105-Y338 AromaticContact CD2-CE1 3.84Å; Y105-Y338 HydrophobicContact CD2-CE1 3.84Å; Y105-Y338 AromaticContact CD2-CE2 3.57Å; Y105-Y338 HydrophobicContact CD2-CE2 3.57Å; Y105-Y338 AromaticContact CD2-CG 3.87Å; Y105-Y338 HydrophobicContact CD2-CG 3.87Å; Y105-Y338 AromaticContact CD2-CZ 3.65Å; Y105-Y338 HydrophobicContact CE2-CD2 4.16Å; Y105-Y338 HydrophobicContact CE2-CE2 4.05Å; Y105-Y338 HydrophobicContact CG-CD1 4.49Å; Y105-Y338 HydrophobicContact CG-CE1 4.22Å; V254-Y338 WeakPolarHBondContact CG1-OH 3.47Å; V254-Y338 PolarHBondContact O-OH 2.99Å; N257-Y338 HydrophobicContact CB-CD2 3.75Å; N257-Y338 HydrophobicContact CB-CE2 3.92Å; A258-Y338 HydrophobicContact CB-CE2 4.07Å; L261-Y338 HydrophobicContact CD1-CD2 3.74Å; L261-Y338 HydrophobicContact CD1-CG 3.9Å; L335-Y338 VanDerWaalsContact O-CB 3.29Å; L335-Y338 WeakPolarHBondContact O-CB 3.45Å; L335-Y338 PolarHBondContact O-N 3.3Å
339R96.6Very high95.2Very high93 Ų9365.1 Ų65.135%0.35133%0.332SS..EExtended strand (participates in β ladder)trans-130132.2167-178.1177.369.9179.64.2109.1F103 L104 S180 I341F103-R339 CarbonylContact C-O 3.57Å; F103-R339 VanDerWaalsContact CA-O 3.31Å; F103-R339 WeakPolarHBondContact CA-O 3.31Å; L104-R339 PolarHBondContact N-O 3.44Å; L104-R339 PolarHBondContact O-N 2.86Å; S180-R339 PolarHBondContact OG-NH2 2.95Å; R339-I341 PolarHBondContact O-N 2.92Å
340R97.7Very high95.4Very high43 Ų4362 Ų6216%0.16232%0.318CS..EExtended strand (participates in β ladder)trans-69121.8172.2-172.3171.764.6-129.3-4.9109.2F103 N332 D345F103-R340 HydrophobicContact CD1-CB 3.91Å; F103-R340 HydrophobicContact CD1-CG 4.4Å; F103-R340 HydrophobicContact CE1-CB 3.76Å; F103-R340 HydrophobicContact CE1-CG 4.03Å; F103-R340 HydrophobicContact CZ-CG 4.33Å; N332-R340 PolarHBondContact OD1-NH1 3.4Å; R340-D345 IonicContact NH2-OD1 3.6Å; R340-D345 PolarHBondContact NH2-OD1 3.28Å
341I97.9Very high95.6Very high10 Ų1066.4 Ų66.45%0.05134%0.339CS..EExtended strand (participates in β ladder)trans-108.7-16.7176.261.8168.8000112.2I102 L104 V183 V184 R339I102-I341 HydrophobicContact CB-CD1 4.49Å; I102-I341 HydrophobicContact CB-CG1 3.99Å; I102-I341 HydrophobicContact CG2-CD1 3.72Å; I102-I341 HydrophobicContact CG2-CG1 3.7Å; I102-I341 WeakPolarHBondContact O-CG1 3.22Å; I102-I341 PolarHBondContact O-N 3.43Å; L104-I341 HydrophobicContact CB-CD1 4.14Å; L104-I341 HydrophobicContact CB-CG1 4.46Å; L104-I341 HydrophobicContact CB-CG2 3.74Å; V183-I341 HydrophobicContact CB-CD1 3.8Å; V183-I341 HydrophobicContact CG1-CD1 3.57Å; V184-I341 HydrophobicContact CG2-CB 4.09Å; V184-I341 HydrophobicContact CG2-CD1 3.64Å; V184-I341 HydrophobicContact CG2-CG1 3.75Å; R339-I341 PolarHBondContact O-N 2.92Å
342Y97.8Very high95.8Very high19 Ų1969.5 Ų69.58%0.07535%0.352CS..EExtended strand (participates in β ladder)trans-145.6133.4170.2-169.8-89.3000111.7L100 R101 I102 V184 L350 Y353 L357L100-Y342 HydrophobicContact CB-CD1 4.05Å; L100-Y342 HydrophobicContact CB-CE1 3.78Å; L100-Y342 HydrophobicContact CD2-CD1 4.02Å; L100-Y342 HydrophobicContact CD2-CE1 3.98Å; L100-Y342 HydrophobicContact CG-CD1 3.75Å; L100-Y342 HydrophobicContact CG-CE1 3.91Å; L100-Y342 VanDerWaalsContact O-CD1 3.26Å; L100-Y342 WeakPolarHBondContact O-CD1 3.12Å; L100-Y342 WeakPolarHBondContact O-CE1 3.35Å; R101-Y342 WeakPolarHBondContact CA-O 3.49Å; I102-Y342 HydrophobicContact CD1-CG 4.23Å; I102-Y342 PolarHBondContact N-O 3.29Å; I102-Y342 PolarHBondContact O-N 2.69Å; V184-Y342 HydrophobicContact CG1-CD2 3.7Å; V184-Y342 HydrophobicContact CG1-CE2 4.5Å; V184-Y342 HydrophobicContact CG1-CG 4.26Å; Y342-L350 HydrophobicContact CE2-CD1 4.06Å; Y342-Y353 AromaticContact CD2-CD2 3.71Å; Y342-Y353 HydrophobicContact CD2-CD2 3.71Å; Y342-Y353 HydrophobicContact CD2-CE2 4.36Å; Y342-Y353 HydrophobicContact CD2-CG 4.34Å; Y342-Y353 AromaticContact CE2-CD2 3.92Å; Y342-Y353 HydrophobicContact CE2-CD2 3.92Å; Y342-Y353 HydrophobicContact CE2-CG 4.23Å; Y342-L357 WeakPolarHBondContact OH-CD1 3.38Å
343P96.4Very high96.1Very high32 Ų3265.5 Ų65.521%0.20833%0.33CS..SBendcis-63.4140.8-10.727.6-35.1000111.2L350P343-L350 HydrophobicContact CB-CD1 3.99Å
344P96Very high96.2Very high19 Ų1963 Ų6312%0.12332%0.319CS..  trans-73.6156.6175.132.8-36.6000110.9D346 L349 L350 Y353P344-D346 VanDerWaalsContact C-N 3.28Å; P344-L349 HydrophobicContact CB-CD2 4.02Å; P344-L349 HydrophobicContact CB-CG 4.44Å; P344-L349 HydrophobicContact CG-CB 4.19Å; P344-L349 HydrophobicContact CG-CD2 4.22Å; P344-L349 HydrophobicContact CG-CG 4.09Å; P344-L350 HydrophobicContact CG-CB 3.97Å; P344-Y353 HydrophobicContact CG-CD2 3.9Å; P344-Y353 HydrophobicContact CG-CE2 3.9Å
345D92.1Very high96.3Very high139 Ų13963.1 Ų63.174%0.74333%0.327SS*.SBendtrans-73.8-23175.1-58-34.3000111.8R340 K347R340-D345 IonicContact NH2-OD1 3.6Å; R340-D345 PolarHBondContact NH2-OD1 3.28Å; D345-K347 PolarHBondContact O-N 3.2Å
346D95.1Very high96.5Very high86 Ų8661.3 Ų61.346%0.4632%0.318SS..  trans-74.6115.1172.6-178.8-10000110.9P344 L348 L349 L350P344-D346 VanDerWaalsContact C-N 3.28Å; D346-L348 PolarHBondContact OD1-N 3.41Å; D346-L349 HydrophobicContact CB-CB 3.89Å; D346-L349 PolarHBondContact O-N 2.84Å; D346-L349 PolarHBondContact OD1-N 2.84Å; D346-L350 PolarHBondContact O-N 2.91Å
347K95.3Very high96.6Very high165 Ų16559.8 Ų59.872%0.71730%0.297SS*.Hα-helixtrans-63.5-39.7179.9-66.1-176.2178.61800113.3D345 L349 L350 E351D345-K347 PolarHBondContact O-N 3.2Å; K347-L349 VanDerWaalsContact C-N 3.31Å; K347-L349 PolarHBondContact O-N 3.47Å; K347-L350 PolarHBondContact O-N 3.2Å; K347-E351 WeakPolarHBondContact O-CG 3.16Å; K347-E351 PolarHBondContact O-N 2.84Å
348L96.7Very high96.5Very high128 Ų12860.4 Ų60.467%0.6731%0.306SS*.Hα-helixtrans-68-38.3-179.6-65.8175.2000110.4D346 K352D346-L348 PolarHBondContact OD1-N 3.41Å; L348-K352 WeakPolarHBondContact O-CB 3.33Å; L348-K352 PolarHBondContact O-N 3.42Å; L348-K352 VanDerWaalsContact O-N 3.08Å
349L96.3Very high96.4Very high38 Ų3860.7 Ų60.720%0.19931%0.309CS..Hα-helixtrans-67.4-38.8174.3-172.959.7000111.8P344 D346 K347 K352 Y353P344-L349 HydrophobicContact CB-CD2 4.02Å; P344-L349 HydrophobicContact CB-CG 4.44Å; P344-L349 HydrophobicContact CG-CB 4.19Å; P344-L349 HydrophobicContact CG-CD2 4.22Å; P344-L349 HydrophobicContact CG-CG 4.09Å; D346-L349 HydrophobicContact CB-CB 3.89Å; D346-L349 PolarHBondContact O-N 2.84Å; D346-L349 PolarHBondContact OD1-N 2.84Å; K347-L349 VanDerWaalsContact C-N 3.31Å; K347-L349 PolarHBondContact O-N 3.47Å; L349-K352 HydrophobicContact CD1-CD 4.35Å; L349-K352 WeakPolarHBondContact O-CB 3.42Å; L349-K352 PolarHBondContact O-N 3.32Å; L349-Y353 HydrophobicContact CD1-CE1 3.99Å; L349-Y353 HydrophobicContact CD1-CE2 4.03Å; L349-Y353 HydrophobicContact CD2-CE2 3.98Å; L349-Y353 HydrophobicContact CG-CD2 4.19Å; L349-Y353 HydrophobicContact CG-CE1 4.47Å; L349-Y353 HydrophobicContact CG-CE2 3.6Å; L349-Y353 WeakPolarHBondContact O-CD2 3.32Å; L349-Y353 PolarHBondContact O-N 3.17Å
350L96.9Very high96.4Very high41 Ų4156.5 Ų56.522%0.21529%0.294CS..Hα-helixtrans-61.6-49174.3178.160.9000111.6Y342 P343 P344 D346 K347 K352 Y353 E354Y342-L350 HydrophobicContact CE2-CD1 4.06Å; P343-L350 HydrophobicContact CB-CD1 3.99Å; P344-L350 HydrophobicContact CG-CB 3.97Å; D346-L350 PolarHBondContact O-N 2.91Å; K347-L350 PolarHBondContact O-N 3.2Å; L350-K352 VanDerWaalsContact C-N 3.27Å; L350-K352 PolarHBondContact O-N 3.4Å; L350-Y353 CarbonylContact O-C 3.59Å; L350-Y353 WeakPolarHBondContact O-CA 3.38Å; L350-Y353 WeakPolarHBondContact O-CB 3.41Å; L350-Y353 PolarHBondContact O-N 3.19Å; L350-E354 HydrophobicContact CD1-CG 4.24Å; L350-E354 HydrophobicContact CG-CG 4.46Å; L350-E354 WeakPolarHBondContact O-CG 3.33Å; L350-E354 PolarHBondContact O-N 3.03Å
351E97.3Very high96.2Very high117 Ų11757.7 Ų57.755%0.54730%0.3SS..Hα-helixtrans-57.1-41.9176.8-74.5173.5-171.300111.6K347 Y353 E354 S355K347-E351 WeakPolarHBondContact O-CG 3.16Å; K347-E351 PolarHBondContact O-N 2.84Å; E351-Y353 PolarHBondContact O-N 2.94Å; E351-E354 PolarHBondContact O-N 3.48Å; E351-S355 PolarHBondContact O-N 2.94Å
352K97.1Very high96Very high68 Ų6863.8 Ų63.830%0.29633%0.329SS..Hα-helixtrans-59.3-46.5173.4179.9-177.9178.5178.30111.5E8 L348 L349 L350 S355 L356E8-K352 WeakPolarHBondContact OE1-CE 3.35Å; E8-K352 IonicContact OE1-NZ 3.09Å; E8-K352 PolarHBondContact OE1-NZ 3.28Å; E8-K352 WeakPolarHBondContact OE2-CE 3.25Å; E8-K352 IonicContact OE2-NZ 2.72Å; E8-K352 PolarHBondContact OE2-NZ 2.85Å; L348-K352 WeakPolarHBondContact O-CB 3.33Å; L348-K352 PolarHBondContact O-N 3.42Å; L348-K352 VanDerWaalsContact O-N 3.08Å; L349-K352 HydrophobicContact CD1-CD 4.35Å; L349-K352 WeakPolarHBondContact O-CB 3.42Å; L349-K352 PolarHBondContact O-N 3.32Å; L350-K352 VanDerWaalsContact C-N 3.27Å; L350-K352 PolarHBondContact O-N 3.4Å; K352-S355 WeakPolarHBondContact O-CB 3.3Å; K352-S355 PolarHBondContact O-N 3.49Å; K352-L356 WeakPolarHBondContact O-CG 3.43Å; K352-L356 PolarHBondContact O-N 2.97Å; K352-L356 VanDerWaalsContact O-N 3.08Å
353Y97.8Very high95.8Very high3 Ų365.3 Ų65.31%0.01234%0.34CS..Hα-helixtrans-66.4-37.3177.9-68.5-30000113.1V184 K185 I188 Y342 P344 L349 L350 E351 S355 L356 L357V184-Y353 HydrophobicContact CB-CE1 4.23Å; V184-Y353 HydrophobicContact CB-CE2 4.15Å; V184-Y353 HydrophobicContact CG1-CD1 3.91Å; V184-Y353 HydrophobicContact CG1-CD2 3.73Å; V184-Y353 HydrophobicContact CG1-CE1 3.83Å; V184-Y353 HydrophobicContact CG1-CE2 3.61Å; V184-Y353 HydrophobicContact CG1-CG 3.87Å; V184-Y353 HydrophobicContact CG2-CE2 4.29Å; K185-Y353 HydrophobicContact CG-CE1 4.24Å; I188-Y353 HydrophobicContact CD1-CD1 3.97Å; I188-Y353 HydrophobicContact CD1-CG 4.09Å; Y342-Y353 AromaticContact CD2-CD2 3.71Å; Y342-Y353 HydrophobicContact CD2-CD2 3.71Å; Y342-Y353 HydrophobicContact CD2-CE2 4.36Å; Y342-Y353 HydrophobicContact CD2-CG 4.34Å; Y342-Y353 AromaticContact CE2-CD2 3.92Å; Y342-Y353 HydrophobicContact CE2-CD2 3.92Å; Y342-Y353 HydrophobicContact CE2-CG 4.23Å; P344-Y353 HydrophobicContact CG-CD2 3.9Å; P344-Y353 HydrophobicContact CG-CE2 3.9Å; L349-Y353 HydrophobicContact CD1-CE1 3.99Å; L349-Y353 HydrophobicContact CD1-CE2 4.03Å; L349-Y353 HydrophobicContact CD2-CE2 3.98Å; L349-Y353 HydrophobicContact CG-CD2 4.19Å; L349-Y353 HydrophobicContact CG-CE1 4.47Å; L349-Y353 HydrophobicContact CG-CE2 3.6Å; L349-Y353 WeakPolarHBondContact O-CD2 3.32Å; L349-Y353 PolarHBondContact O-N 3.17Å; L350-Y353 CarbonylContact O-C 3.59Å; L350-Y353 WeakPolarHBondContact O-CA 3.38Å; L350-Y353 WeakPolarHBondContact O-CB 3.41Å; L350-Y353 PolarHBondContact O-N 3.19Å; E351-Y353 PolarHBondContact O-N 2.94Å; Y353-S355 VanDerWaalsContact C-N 3.34Å; Y353-S355 PolarHBondContact O-N 2.88Å; Y353-L356 HydrophobicContact CD1-CD1 4.49Å; Y353-L356 PolarHBondContact O-N 2.93Å; Y353-L357 PolarHBondContact O-N 3.47Å
354E96.4Very high95.6Very high97 Ų9765 Ų6545%0.45334%0.335SS..Hα-helixtrans-64.3-38175-71.7180170.300112.2L350 E351 L357 S358L350-E354 HydrophobicContact CD1-CG 4.24Å; L350-E354 HydrophobicContact CG-CG 4.46Å; L350-E354 WeakPolarHBondContact O-CG 3.33Å; L350-E354 PolarHBondContact O-N 3.03Å; E351-E354 PolarHBondContact O-N 3.48Å; E354-L357 PolarHBondContact O-N 3.22Å; E354-S358 PolarHBondContact O-N 3.41Å; E354-S358 PolarHBondContact O-OG 2.99Å
355S96.8Very high95.4Very high71 Ų7169.3 Ų69.350%0.49736%0.357SS..Hα-helixtrans-61.8-43.1170.9-179.60000111.7E351 K352 Y353 S358 A359E351-S355 PolarHBondContact O-N 2.94Å; K352-S355 WeakPolarHBondContact O-CB 3.3Å; K352-S355 PolarHBondContact O-N 3.49Å; Y353-S355 VanDerWaalsContact C-N 3.34Å; Y353-S355 PolarHBondContact O-N 2.88Å; S355-S358 WeakPolarHBondContact O-CB 3.28Å; S355-S358 PolarHBondContact O-N 3.4Å; S355-A359 PolarHBondContact O-N 3.4Å
356L97.2Very high95.3Very high4 Ų465.7 Ų65.72%0.02135%0.346CS..Hα-helixtrans-66.8-38.3175.9-69-177.3000113.2Q5 E8 Y9 K185 I188 K352 Y353 A359 A360Q5-L356 HydrophobicContact CB-CD2 4.34Å; Q5-L356 HydrophobicContact CG-CD2 3.9Å; E8-L356 HydrophobicContact CB-CD1 4.39Å; E8-L356 HydrophobicContact CB-CD2 4.3Å; E8-L356 HydrophobicContact CG-CD1 4.45Å; E8-L356 HydrophobicContact CG-CD2 4.14Å; Y9-L356 HydrophobicContact CE2-CD2 4.16Å; K185-L356 HydrophobicContact CD-CD1 4.3Å; K185-L356 HydrophobicContact CG-CD1 3.95Å; I188-L356 HydrophobicContact CD1-CB 4.26Å; I188-L356 HydrophobicContact CG2-CB 4.09Å; K352-L356 WeakPolarHBondContact O-CG 3.43Å; K352-L356 PolarHBondContact O-N 2.97Å; K352-L356 VanDerWaalsContact O-N 3.08Å; Y353-L356 HydrophobicContact CD1-CD1 4.49Å; Y353-L356 PolarHBondContact O-N 2.93Å; L356-A359 PolarHBondContact O-N 3.49Å; L356-A360 WeakPolarHBondContact O-CB 3.24Å; L356-A360 PolarHBondContact O-N 3.15Å
357L96.3Very high94.7Very high22 Ų2263.7 Ų63.712%0.11535%0.346CS..Hα-helixtrans-59.3-49.1171.8-82.2165.4000110.5I188 E191 Y342 Y353 E354 A359 A360 F361I188-L357 HydrophobicContact CB-CD2 4.15Å; I188-L357 HydrophobicContact CB-CG 4.41Å; I188-L357 HydrophobicContact CD1-CG 4.18Å; I188-L357 HydrophobicContact CG1-CD2 3.87Å; I188-L357 HydrophobicContact CG1-CG 3.84Å; I188-L357 HydrophobicContact CG2-CD2 3.91Å; I188-L357 HydrophobicContact CG2-CG 3.98Å; E191-L357 HydrophobicContact CB-CD2 3.85Å; E191-L357 HydrophobicContact CG-CD2 3.61Å; Y342-L357 WeakPolarHBondContact OH-CD1 3.38Å; Y353-L357 PolarHBondContact O-N 3.47Å; E354-L357 PolarHBondContact O-N 3.22Å; L357-A359 VanDerWaalsContact C-N 3.3Å; L357-A359 PolarHBondContact O-N 3.45Å; L357-A360 WeakPolarHBondContact O-CA 3.43Å; L357-A360 WeakPolarHBondContact O-CB 3.38Å; L357-A360 PolarHBondContact O-N 3.24Å; L357-F361 HydrophobicContact CD2-CE2 4.39Å; L357-F361 VanDerWaalsContact O-CD2 3.31Å; L357-F361 WeakPolarHBondContact O-CD2 3.45Å; L357-F361 PolarHBondContact O-N 3.07Å
358S95.1Very high93.8Very high69 Ų6960.8 Ų60.848%0.48333%0.33SS..Hα-helixtrans-55.8-45.6177.3-61.60000111.7E354 S355 A360 F361 Q362E354-S358 PolarHBondContact O-N 3.41Å; E354-S358 PolarHBondContact O-OG 2.99Å; S355-S358 WeakPolarHBondContact O-CB 3.28Å; S355-S358 PolarHBondContact O-N 3.4Å; S358-A360 PolarHBondContact O-N 2.82Å; S358-F361 PolarHBondContact O-N 3.33Å; S358-Q362 VanDerWaalsContact O-CG 3.32Å; S358-Q362 WeakPolarHBondContact O-CG 3.36Å; S358-Q362 PolarHBondContact O-N 3.24Å
359A95.4Very high92.3Very high11 Ų1157 Ų579%0.09132%0.318CS..Hα-helixtrans-64.3-36.4175.200000113.2M1 S355 L356 L357 T363M1-A359 HydrophobicContact CE-CB 4.36Å; S355-A359 PolarHBondContact O-N 3.4Å; L356-A359 PolarHBondContact O-N 3.49Å; L357-A359 VanDerWaalsContact C-N 3.3Å; L357-A359 PolarHBondContact O-N 3.45Å; A359-T363 WeakPolarHBondContact O-CB 3.33Å; A359-T363 PolarHBondContact O-N 3.16Å; A359-T363 PolarHBondContact O-OG1 2.8Å
360A95.9Very high90.6Very high4 Ų457.4 Ų57.43%0.03333%0.326CS..Hα-helixtrans-65.9-45.9175.800000111.6M1 I188 P192 L356 L357 S358 T363 F364M1-A360 HydrophobicContact CE-CB 3.96Å; M1-A360 HydrophobicContact SD-CB 4.07Å; I188-A360 HydrophobicContact CG2-CB 4.06Å; I188-A360 WeakPolarHBondContact O-CB 3.43Å; P192-A360 HydrophobicContact CG-CB 4.26Å; L356-A360 WeakPolarHBondContact O-CB 3.24Å; L356-A360 PolarHBondContact O-N 3.15Å; L357-A360 WeakPolarHBondContact O-CA 3.43Å; L357-A360 WeakPolarHBondContact O-CB 3.38Å; L357-A360 PolarHBondContact O-N 3.24Å; S358-A360 PolarHBondContact O-N 2.82Å; A360-T363 PolarHBondContact O-N 3.47Å; A360-F364 WeakPolarHBondContact O-CB 3.33Å; A360-F364 PolarHBondContact O-N 3.03Å
361F94.3Very high88.9Confident68 Ų6858.5 Ų58.530%0.29834%0.338SS..Hα-helixtrans-61.5-43.4174.8-86.2-86.5000112.2E191 P192 L195 L357 S358 T363 F364 L365E191-F361 HydrophobicContact CG-CE2 4.15Å; E191-F361 HydrophobicContact CG-CZ 4.37Å; P192-F361 HydrophobicContact CB-CD1 3.65Å; P192-F361 HydrophobicContact CB-CD2 4.18Å; P192-F361 HydrophobicContact CB-CE1 3.64Å; P192-F361 HydrophobicContact CB-CE2 4.16Å; P192-F361 HydrophobicContact CB-CG 3.92Å; P192-F361 HydrophobicContact CB-CZ 3.89Å; L195-F361 HydrophobicContact CD2-CE1 4.14Å; L195-F361 HydrophobicContact CD2-CZ 3.71Å; L357-F361 HydrophobicContact CD2-CE2 4.39Å; L357-F361 VanDerWaalsContact O-CD2 3.31Å; L357-F361 WeakPolarHBondContact O-CD2 3.45Å; L357-F361 PolarHBondContact O-N 3.07Å; S358-F361 PolarHBondContact O-N 3.33Å; F361-T363 PolarHBondContact O-N 3.46Å; F361-F364 PolarHBondContact O-N 3.19Å; F361-L365 VanDerWaalsContact O-CG 3.31Å; F361-L365 WeakPolarHBondContact O-CG 3.1Å; F361-L365 PolarHBondContact O-N 3.41Å
362Q93.9Very high86.8Confident138 Ų13857.1 Ų57.165%0.64533%0.334SS*.Hα-helixtrans-59.9-45.1174.7-74175.8-6.300111.8S358 F364 L365 A366S358-Q362 VanDerWaalsContact O-CG 3.32Å; S358-Q362 WeakPolarHBondContact O-CG 3.36Å; S358-Q362 PolarHBondContact O-N 3.24Å; Q362-F364 PolarHBondContact O-N 3.3Å; Q362-L365 PolarHBondContact O-N 3.48Å; Q362-A366 WeakPolarHBondContact O-CB 3.37Å; Q362-A366 PolarHBondContact O-N 2.96Å
363T93.4Very high84.7Confident52 Ų5259.8 Ų59.832%0.31935%0.347SS..Hα-helixtrans-62.9-42.4177.6-57.20000111.5A359 A360 F361 A366 G367A359-T363 WeakPolarHBondContact O-CB 3.33Å; A359-T363 PolarHBondContact O-N 3.16Å; A359-T363 PolarHBondContact O-OG1 2.8Å; A360-T363 PolarHBondContact O-N 3.47Å; F361-T363 PolarHBondContact O-N 3.46Å; T363-A366 PolarHBondContact O-N 2.93Å; T363-G367 PolarHBondContact O-N 3.36Å
364F93Very high82.7Confident24 Ų2467.6 Ų67.611%0.10538%0.381CS..Hα-helixtrans-60.6-46.9176.9171.4-106.2000112P192 H193 H196 A360 F361 Q362 G367 R368P192-F364 HydrophobicContact CB-CB 3.79Å; P192-F364 HydrophobicContact CB-CD1 3.95Å; P192-F364 HydrophobicContact CB-CD2 4.37Å; P192-F364 HydrophobicContact CB-CG 3.79Å; P192-F364 HydrophobicContact CG-CB 3.94Å; P192-F364 HydrophobicContact CG-CG 4.31Å; H193-F364 HydrophobicContact CB-CE2 4.48Å; H193-F364 AromaticContact CD2-CD2 3.88Å; H193-F364 AromaticContact CE1-CD2 3.49Å; H193-F364 VanDerWaalsContact CE1-CD2 3.49Å; H193-F364 WeakPolarHBondContact CE1-CD2 3.34Å; H193-F364 AromaticContact CE1-CE2 3.81Å; H193-F364 AromaticContact CG-CD2 3.9Å; H193-F364 AromaticContact CG-CE2 3.86Å; H193-F364 AromaticContact ND1-CD2 3.66Å; H193-F364 AromaticContact ND1-CE2 3.52Å; H193-F364 AromaticContact NE2-CD2 3.61Å; H196-F364 HydrophobicContact CB-CE1 4.29Å; H196-F364 HydrophobicContact CB-CZ 4.02Å; A360-F364 WeakPolarHBondContact O-CB 3.33Å; A360-F364 PolarHBondContact O-N 3.03Å; F361-F364 PolarHBondContact O-N 3.19Å; Q362-F364 PolarHBondContact O-N 3.3Å; F364-G367 PolarHBondContact O-N 2.95Å; F364-R368 HydrophobicContact CE2-CG 4.28Å; F364-R368 VanDerWaalsContact CZ-CD 3.44Å; F364-R368 HydrophobicContact CZ-CG 4.31Å; F364-R368 PolarHBondContact O-N 2.87Å
365L91Very high80.7Confident110 Ų11067.4 Ų67.458%0.57638%0.38SS*.Hα-helixtrans-63.6-43.2178-69.8172.5000111.8F361 Q362 G367 R368 A369F361-L365 VanDerWaalsContact O-CG 3.31Å; F361-L365 WeakPolarHBondContact O-CG 3.1Å; F361-L365 PolarHBondContact O-N 3.41Å; Q362-L365 PolarHBondContact O-N 3.48Å; L365-G367 VanDerWaalsContact C-N 3.33Å; L365-G367 PolarHBondContact O-N 2.94Å; L365-R368 PolarHBondContact O-N 3.26Å; L365-A369 WeakPolarHBondContact O-CB 3.49Å; L365-A369 PolarHBondContact O-N 3.13Å
366A89.6Confident78.3Confident63 Ų6370.2 Ų70.252%0.52139%0.387SS..Hα-helixtrans-60.3-42176.300000112.1Q362 T363 A370Q362-A366 WeakPolarHBondContact O-CB 3.37Å; Q362-A366 PolarHBondContact O-N 2.96Å; T363-A366 PolarHBondContact O-N 2.93Å; A366-A370 PolarHBondContact O-N 3.34Å; A366-A370 VanDerWaalsContact O-N 3.12Å
367G83.3Confident76.1Confident44 Ų4475.8 Ų75.845%0.45442%0.417SS..Hα-helixtrans-64.3-42.2176.900000113.2T363 F364 L365 S371T363-G367 PolarHBondContact O-N 3.36Å; F364-G367 PolarHBondContact O-N 2.95Å; L365-G367 VanDerWaalsContact C-N 3.33Å; L365-G367 PolarHBondContact O-N 2.94Å; G367-S371 WeakPolarHBondContact O-CB 3.37Å; G367-S371 PolarHBondContact O-N 3.48Å
368R76.8Confident74.4Confident104 Ų10477.9 Ų77.939%0.39243%0.428SS..Hα-helixtrans-69.6-40177.1-73.3-168.271.4-175.610112.9H196 F364 L365 A370 S371 L372H196-R368 PolarHBondContact CD2-NH1 2.72Å; H196-R368 PolarHBondContact CE1-NH1 2.99Å; H196-R368 PolarHBondContact NE2-NH1 3.27Å; F364-R368 HydrophobicContact CE2-CG 4.28Å; F364-R368 VanDerWaalsContact CZ-CD 3.44Å; F364-R368 HydrophobicContact CZ-CG 4.31Å; F364-R368 PolarHBondContact O-N 2.87Å; L365-R368 PolarHBondContact O-N 3.26Å; R368-A370 VanDerWaalsContact C-N 3.32Å; R368-A370 PolarHBondContact O-N 3.29Å; R368-S371 PolarHBondContact O-N 3.35Å; R368-L372 WeakPolarHBondContact O-CB 3.41Å; R368-L372 WeakPolarHBondContact O-CG 3.46Å; R368-L372 PolarHBondContact O-N 3.05Å
369A63.6Low72.3Confident49 Ų4978.9 Ų78.941%0.40543%0.433SS..Hα-helixtrans-59.5-44.9175.300000111.2L365 L372 Q373L365-A369 WeakPolarHBondContact O-CB 3.49Å; L365-A369 PolarHBondContact O-N 3.13Å; A369-L372 PolarHBondContact O-N 3.28Å; A369-Q373 WeakPolarHBondContact O-CB 3.35Å; A369-Q373 WeakPolarHBondContact O-CG 3.42Å; A369-Q373 PolarHBondContact O-N 2.88Å
370A61.9Low70.2Confident46 Ų4684.4 Ų84.438%0.3846%0.461SS..Hα-helixtrans-65.4-37.7175.500000112.7A366 R368 K374A366-A370 PolarHBondContact O-N 3.34Å; A366-A370 VanDerWaalsContact O-N 3.12Å; R368-A370 VanDerWaalsContact C-N 3.32Å; R368-A370 PolarHBondContact O-N 3.29Å; A370-K374 WeakPolarHBondContact O-CB 3.37Å; A370-K374 WeakPolarHBondContact O-CG 3.46Å; A370-K374 PolarHBondContact O-N 3.13Å
371S60.1Low68.1Low65 Ų6589.8 Ų89.846%0.45548%0.483SS..Hα-helixtrans-66.2-45.7175.2-170.50000112G367 R368 K374 E375G367-S371 WeakPolarHBondContact O-CB 3.37Å; G367-S371 PolarHBondContact O-N 3.48Å; R368-S371 PolarHBondContact O-N 3.35Å; S371-K374 PolarHBondContact O-N 3.28Å; S371-E375 WeakPolarHBondContact O-CG 3.42Å; S371-E375 PolarHBondContact O-N 2.87Å
372L53.9Low66Low88 Ų8894.6 Ų94.646%0.46150%0.499SS..Hα-helixtrans-64-41.5177.5-73.7167.5000111.3R368 A369 E375 M376R368-L372 WeakPolarHBondContact O-CB 3.41Å; R368-L372 WeakPolarHBondContact O-CG 3.46Å; R368-L372 PolarHBondContact O-N 3.05Å; A369-L372 PolarHBondContact O-N 3.28Å; L372-E375 PolarHBondContact O-N 3.23Å; L372-M376 WeakPolarHBondContact O-CB 3.49Å; L372-M376 VanDerWaalsContact O-CG 3.24Å; L372-M376 WeakPolarHBondContact O-CG 3.22Å; L372-M376 PolarHBondContact O-N 3.02Å
373Q52.3Low63.6Low124 Ų12494.8 Ų94.858%0.57950%0.502SS*.Hα-helixtrans-62.8-40.9173-76176.9-11.400112.2A369 M376 N377A369-Q373 WeakPolarHBondContact O-CB 3.35Å; A369-Q373 WeakPolarHBondContact O-CG 3.42Å; A369-Q373 PolarHBondContact O-N 2.88Å; Q373-M376 PolarHBondContact O-N 3.29Å; Q373-N377 VanDerWaalsContact O-CB 3.25Å; Q373-N377 WeakPolarHBondContact O-CB 3.46Å; Q373-N377 VanDerWaalsContact O-CG 3.29Å; Q373-N377 PolarHBondContact O-N 2.97Å; Q373-N377 PolarHBondContact O-ND2 2.76Å
374K56.9Low61.4Low166 Ų166100.1 Ų100.172%0.72252%0.521SS*.Hα-helixtrans-64-39.5173.3-83.3-177177.5-178.50112.5A370 S371 N378A370-K374 WeakPolarHBondContact O-CB 3.37Å; A370-K374 WeakPolarHBondContact O-CG 3.46Å; A370-K374 PolarHBondContact O-N 3.13Å; S371-K374 PolarHBondContact O-N 3.28Å; K374-N378 PolarHBondContact O-N 3.41Å
375E53.5Low59.1Low93 Ų93101.9 Ų101.944%0.43554%0.539SS..Hα-helixtrans-67.5-40.7175-75.4-158.2110.500112.4S371 L372 N377 N378 K381S371-E375 WeakPolarHBondContact O-CG 3.42Å; S371-E375 PolarHBondContact O-N 2.87Å; L372-E375 PolarHBondContact O-N 3.23Å; E375-N377 VanDerWaalsContact C-N 3.31Å; E375-N377 PolarHBondContact O-N 3.36Å; E375-N378 WeakPolarHBondContact O-CB 3.43Å; E375-N378 PolarHBondContact O-N 3.01Å; E375-K381 IonicContact OE1-NZ 3.91Å; E375-K381 PolarHBondContact OE1-NZ 3.47Å
376M46.6Very low56.6Low131 Ų131106.6 Ų106.665%0.64555%0.55SS*.Hα-helixtrans-67.2-31.8176.3-73.917667.100112.9L372 Q373L372-M376 WeakPolarHBondContact O-CB 3.49Å; L372-M376 VanDerWaalsContact O-CG 3.24Å; L372-M376 WeakPolarHBondContact O-CG 3.22Å; L372-M376 PolarHBondContact O-N 3.02Å; Q373-M376 PolarHBondContact O-N 3.29Å
377N51.6Low54.3Low121 Ų121107.9 Ų107.965%0.64755%0.551SS**THydrogen-bonded Turntrans-89.32.1178-71.8-15.4000113.5Q373 E375 P379Q373-N377 VanDerWaalsContact O-CB 3.25Å; Q373-N377 WeakPolarHBondContact O-CB 3.46Å; Q373-N377 VanDerWaalsContact O-CG 3.29Å; Q373-N377 PolarHBondContact O-N 2.97Å; Q373-N377 PolarHBondContact O-ND2 2.76Å; E375-N377 VanDerWaalsContact C-N 3.31Å; E375-N377 PolarHBondContact O-N 3.36Å; N377-P379 WeakPolarHBondContact O-CD 3.28Å
378N60Low52.2Low65 Ų65109.4 Ų109.435%0.34856%0.555SS.*  trans-77.2109.1176.1-171.6-12.1000110.5K374 E375 L380 K381K374-N378 PolarHBondContact O-N 3.41Å; E375-N378 WeakPolarHBondContact O-CB 3.43Å; E375-N378 PolarHBondContact O-N 3.01Å; N378-L380 PolarHBondContact O-N 2.95Å; N378-L380 PolarHBondContact OD1-N 3.35Å; N378-K381 PolarHBondContact O-N 2.96Å
379P50.9Low50.5Low90 Ų90110 Ų11058%0.58457%0.569SS**Hα-helixtrans-64.6-25.1-174.124.3-31.6000113.3N377 K381 R382 M383N377-P379 WeakPolarHBondContact O-CD 3.28Å; P379-K381 PolarHBondContact O-N 3.46Å; P379-R382 PolarHBondContact O-N 2.95Å; P379-M383 PolarHBondContact O-N 3.42Å; P379-M383 VanDerWaalsContact O-N 3.15Å
380L51.3Low49.2Very low128 Ų128111.2 Ų111.267%0.6758%0.58SS**Hα-helixtrans-67.6-30.6-179.9-76.3155.6000113.3N378 K384N378-L380 PolarHBondContact O-N 2.95Å; N378-L380 PolarHBondContact OD1-N 3.35Å; L380-K384 PolarHBondContact O-N 3.09Å
381K52.6Low48Very low117 Ų117116 Ų11651%0.50960%0.599SS.*Hα-helixtrans-78.2-31.8173.5-86.6-175.5177.5177.40112E375 N378 P379 M383 K384 A385E375-K381 IonicContact OE1-NZ 3.91Å; E375-K381 PolarHBondContact OE1-NZ 3.47Å; N378-K381 PolarHBondContact O-N 2.96Å; P379-K381 PolarHBondContact O-N 3.46Å; K381-M383 VanDerWaalsContact C-N 3.33Å; K381-M383 PolarHBondContact O-N 2.88Å; K381-K384 PolarHBondContact O-N 3.35Å; K381-A385 PolarHBondContact O-N 3.11Å; K381-A385 VanDerWaalsContact O-N 3.07Å
382R48.9Very low46.9Very low169 Ų169117.7 Ų117.764%0.63861%0.61SS**Hα-helixtrans-65-34.4173.5-81.7-174.7175.9-170.6-2.2112.6P379 R386P379-R382 PolarHBondContact O-N 2.95Å; R382-R386 PolarHBondContact O-N 2.84Å
383M45.3Very low46.1Very low141 Ų141122.5 Ų122.570%0.69563%0.63SS**Hα-helixtrans-70-44.1174-77.7-177.374.800112.2P379 K381 A385 R386 T387P379-M383 PolarHBondContact O-N 3.42Å; P379-M383 VanDerWaalsContact O-N 3.15Å; K381-M383 VanDerWaalsContact C-N 3.33Å; K381-M383 PolarHBondContact O-N 2.88Å; M383-A385 VanDerWaalsContact C-N 3.33Å; M383-A385 PolarHBondContact O-N 3.06Å; M383-R386 PolarHBondContact O-N 3.11Å; M383-R386 VanDerWaalsContact O-N 3.16Å; M383-T387 PolarHBondContact O-N 2.84Å; M383-T387 PolarHBondContact O-OG1 2.99Å
384K46.2Very low45.2Very low165 Ų165119.4 Ų119.472%0.71763%0.631SS**Hα-helixtrans-63.7-34.1177.2-76.9-171.6175.9-173.50113.9L380 K381 T387 S388L380-K384 PolarHBondContact O-N 3.09Å; K381-K384 PolarHBondContact O-N 3.35Å; K384-T387 PolarHBondContact O-OG1 3.22Å; K384-S388 PolarHBondContact O-N 2.89Å
385A44.5Very low44Very low60 Ų60120.3 Ų120.350%0.49664%0.637SS.*Hα-helixtrans-69.4-32.6175.100000112.5K381 M383 S388K381-A385 PolarHBondContact O-N 3.11Å; K381-A385 VanDerWaalsContact O-N 3.07Å; M383-A385 VanDerWaalsContact C-N 3.33Å; M383-A385 PolarHBondContact O-N 3.06Å; A385-S388 PolarHBondContact O-OG 3.31Å; A385-S388 VanDerWaalsContact O-OG 3.13Å
386R39.6Very low42.9Very low210 Ų210122.2 Ų122.279%0.79266%0.656SS**Hα-helixtrans-79.3-31.2178-76.4-176.7174.6-172.5-2.6113.6R382 M383R382-R386 PolarHBondContact O-N 2.84Å; M383-R386 PolarHBondContact O-N 3.11Å; M383-R386 VanDerWaalsContact O-N 3.16Å
387T40.5Very low42.2Very low89 Ų89124.1 Ų124.155%0.54666%0.663SS.*Hα-helixtrans-75-28.2174.131.60000113.2M383 K384 V389 A390M383-T387 PolarHBondContact O-N 2.84Å; M383-T387 PolarHBondContact O-OG1 2.99Å; K384-T387 PolarHBondContact O-OG1 3.22Å; T387-V389 VanDerWaalsContact C-N 3.25Å; T387-V389 PolarHBondContact O-N 2.99Å; T387-A390 PolarHBondContact O-N 2.71Å
388S39.3Very low41.2Very low76 Ų76124 Ų12453%0.53167%0.666SS.*THydrogen-bonded Turntrans-70.3-15.3178.672.40000115.4K384 A385K384-S388 PolarHBondContact O-N 2.89Å; A385-S388 PolarHBondContact O-OG 3.31Å; A385-S388 VanDerWaalsContact O-OG 3.13Å
389V40.6Very low39.7Very low116 Ų116129.6 Ų129.670%0.70369%0.69SS**THydrogen-bonded Turntrans-93.9-16.5179.7-175.10000111.8T387T387-V389 VanDerWaalsContact C-N 3.25Å; T387-V389 PolarHBondContact O-N 2.99Å
390A36.8Very low38.6Very low75 Ų75131.1 Ų131.162%0.6270%0.698SS**THydrogen-bonded Turntrans-87.2-21.2-17800000114.1T387T387-A390 PolarHBondContact O-N 2.71Å
391D36.8Very low37.5Very low147 Ų147132.3 Ų132.379%0.78671%0.705SS**THydrogen-bonded Turntrans-94.16.8-175.2-73.2-21.2000114.6
392C36.4Very low36.5Very low101 Ų101132.9 Ų132.968%0.68272%0.718SS**THydrogen-bonded Turntrans-93.74.6179.1-70.10000114.7
393H37.3Very low35.4Very low189 Ų189130.6 Ų130.688%0.87573%0.727SS**SBendtrans-130.776.5178.6-78.940.8000111.3
394G34Very low34.7Very low59 Ų59129 Ų12961%0.60873%0.728SS**SBendtrans158.482.6168.800000113.2
395H30.8Very low33.8Very low184 Ų184130 Ų13085%0.85273%0.733SS**  trans164.988.3133.6-82.9-41.5000110.4H397H395-H397 PolarHBondContact O-N 2.96Å
396T32Very low32.9Very low134 Ų134133.9 Ų133.982%0.82275%0.745SS**  trans-73.1104.6150.343.20000108
397H30.2Very low32.6Very low171 Ų171135.8 Ų135.879%0.79277%0.77SS**  trans-144.2122.8151.5-93.4-59.6000111.3H395H395-H397 PolarHBondContact O-N 2.96Å
398T31Very low32.3Very low117 Ų117138.2 Ų138.272%0.71878%0.781SS**  trans-52.3130.8168.345.10000112.5
399H28Very low31.9Very low183 Ų183141.4 Ų141.485%0.84779%0.794SS**  trans-157.1119.9138.7-97.5-59.3000111.6
400T29.5Very low31.4Very low122 Ų122142.8 Ų142.875%0.74880%0.799SS**  trans-61.7131.4160.944.20000110.9
401N27.9Very low31.1Very low154 Ų154146.8 Ų146.882%0.82481%0.81SS**  trans-171.3127.7130.5-102.5-15.3000113.2
402T30.6Very low30.7Very low129 Ų129146.8 Ų146.879%0.79181%0.811SS**  trans-48.3137.9157.933.40000114
403C27.2Very low30.3Very low121 Ų121149.9 Ų149.982%0.81882%0.82SS**  trans-164.8121.4136.2-148.40000113.1
404C29.1Very low29.9Very low107 Ų107147.1 Ų147.172%0.72382%0.816SS**  trans19.7123.5140.9-67.20000120.1
405K26.9Very low29.5Very low186 Ų186153.8 Ų153.881%0.80983%0.832SS**  60.9108.587.7-84-171.5-179.2179.90114.8
406N27.1Very low29.4Very low142 Ų142151.3 Ų151.376%0.75983%0.83SS**  141.2141.6116.2-80.2-15.2000114.5
407L33.9Very low29.2Very low250 Ų250152.9 Ų152.9100%1.30983%0.831SS**  trans85.30164.9-70.1155.3000117.6

Retrieved 407 of 407 residues in 442.7 ms (Link to these results)