A0A096MGI8_POEFO Loading...

Unc-93 homolog B1, TLR signaling regulator

AlphaFold DB , UniProt , Accession A0A096MGI8, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 621 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	M	33.1	Very low	31.1	Very low	245 Å²	245	155.8 Å²	155.8	100%	1.207	84%	0.843	S	S	*	*				0	134.7	0	-77.2	170	170	0	0	106.9
2	E	32.7	Very low	31	Very low	191 Å²	191	155.2 Å²	155.2	89%	0.893	84%	0.839	S	S	*	*			trans	-63.3	174.2	-174.5	-68	142.2	128.5	0	0	113.2
3	A	35.8	Very low	31	Very low	79 Å²	79	150.6 Å²	150.6	65%	0.653	83%	0.826	S	S	*	*			cis	-172.4	161.9	-27.7	0	0	0	0	0	104.6
4	T	33.3	Very low	31	Very low	123 Å²	123	150.3 Å²	150.3	76%	0.755	82%	0.823	S	S	*	*				171.4	147.6	71.3	35.2	0	0	0	0	109.4
5	V	35	Very low	30.9	Very low	131 Å²	131	151.1 Å²	151.1	79%	0.794	82%	0.818	S	S	*	*			trans	42.4	129.3	132.5	-171.8	0	0	0	0	119
6	G	29.6	Very low	30.7	Very low	68 Å²	68	149 Å²	149	70%	0.701	81%	0.812	S	S	*	*			cis	-166	-155.7	3.1	0	0	0	0	0	108.1
7	E	29.2	Very low	30.6	Very low	177 Å²	177	148.2 Å²	148.2	83%	0.827	81%	0.813	S	S	*	*			cis	-161.6	-177.3	-8.7	-149.6	126.3	106	0	0	108.4
8	Q	28.1	Very low	30.6	Very low	187 Å²	187	144.7 Å²	144.7	87%	0.874	81%	0.806	S	S	*	*			trans	-143.8	153.2	-167.1	-69.9	-178.1	-57.6	0	0	117.9
9	L	28.2	Very low	31	Very low	169 Å²	169	143.6 Å²	143.6	89%	0.885	81%	0.806	S	S	*	*			trans	-76.3	151	160.8	-71.2	81.8	0	0	0	111.5
10	I	29.3	Very low	31.7	Very low	171 Å²	171	141.6 Å²	141.6	88%	0.877	80%	0.799	S	S	*	*			trans	-143.7	147.6	151	-60.1	-173.3	0	0	0	110.1
11	E	27.6	Very low	31.6	Very low	173 Å²	173	142.5 Å²	142.5	81%	0.808	80%	0.802	S	S	*	*			trans	-126.4	143.3	-176.7	-169.7	177.6	-152.2	0	0	110.1
12	D	30.3	Very low	31.3	Very low	148 Å²	148	134.9 Å²	134.9	79%	0.791	79%	0.786	S	S	*	*			trans	37.3	136.4	159.1	-84	2.6	0	0	0	123.3
13	S	31.3	Very low	31	Very low	96 Å²	96	129.8 Å²	129.8	67%	0.671	79%	0.785	S	S	*	*				172	157	64.9	38.8	0	0	0	0	114.4
14	N	30.4	Very low	30.7	Very low	146 Å²	146	130.5 Å²	130.5	78%	0.781	79%	0.791	S	S	*	*			trans	67.9	148.5	152.3	-74.5	-31.5	0	0	0	120.2
15	Q	29.9	Very low	30.6	Very low	162 Å²	162	130.2 Å²	130.2	76%	0.757	79%	0.794	S	S	*	*			cis	-167.4	154.8	10.4	-132	-172.8	14.7	0	0	115.6
16	V	28.2	Very low	30.4	Very low	118 Å²	118	133.3 Å²	133.3	72%	0.715	80%	0.8	S	S	*	*			trans	58.6	132	153.4	-150.9	0	0	0	0	124.2
17	V	27.6	Very low	30.8	Very low	136 Å²	136	137.6 Å²	137.6	82%	0.824	81%	0.806	S	S	*	*				155.9	135.2	122.5	168	0	0	0	0	113.4
18	A	30.5	Very low	30.9	Very low	84 Å²	84	137.1 Å²	137.1	69%	0.694	81%	0.808	S	S	*	*			trans	-98.3	175.8	176.8	0	0	0	0	0	112
19	P	38.5	Very low	31.6	Very low	124 Å²	124	135 Å²	135	81%	0.805	80%	0.803	S	S	*	*				-151	-133.7	60.5	34.2	-4.6	0	0	0	115.3
20	P	45.2	Very low	32.1	Very low	104 Å²	104	133.4 Å²	133.4	68%	0.675	80%	0.799	S	S	*	*				-133	-167.7	-102	45.3	-26.7	0	0	0	117.1
21	N	30.9	Very low	32.7	Very low	161 Å²	161	128.1 Å²	128.1	86%	0.861	79%	0.788	S	S	*	*			trans	79.4	117.4	157.3	-75.4	-4.4	0	0	0	121.7
22	G	26	Very low	33.2	Very low	84 Å²	84	126.8 Å²	126.8	87%	0.866	78%	0.781	S	S	*	*				113.6	130.4	105.1	0	0	0	0	0	118.7
23	G	26.6	Very low	33.6	Very low	84 Å²	84	128 Å²	128	87%	0.866	78%	0.782	S	S	*	*			trans	122.8	118.9	163.3	0	0	0	0	0	114.1
24	A	29.8	Very low	34.1	Very low	95 Å²	95	125.8 Å²	125.8	79%	0.785	78%	0.775	S	S	*	*			trans	-97.1	149.2	176.2	0	0	0	0	0	111.8
25	S	30.7	Very low	34.5	Very low	116 Å²	116	125.9 Å²	125.9	81%	0.811	77%	0.771	S	S	*	*			trans	33.9	114.6	154.4	-55	0	0	0	0	120.3
26	E	30.4	Very low	35	Very low	197 Å²	197	123.7 Å²	123.7	92%	0.921	76%	0.762	S	S	*	*				-141.3	144.2	129.8	-126.3	174.6	176.5	0	0	110
27	L	38.7	Very low	35.7	Very low	157 Å²	157	125.4 Å²	125.4	82%	0.822	76%	0.762	S	S	*	*			trans	-71.6	145.7	-172.5	-79	72.2	0	0	0	111.8
28	L	30.8	Very low	36.6	Very low	167 Å²	167	127.1 Å²	127.1	87%	0.874	76%	0.761	S	S	*	*			trans	-154.1	102.9	133	-112	165.6	0	0	0	110.4
29	D	42.3	Very low	37.2	Very low	144 Å²	144	132.3 Å²	132.3	77%	0.77	77%	0.768	S	S	*	*			trans	-75.4	115	171.4	163.5	33.8	0	0	0	110.2
30	V	39.9	Very low	37.8	Very low	134 Å²	134	133.2 Å²	133.2	81%	0.812	77%	0.766	S	S	*	*			trans	-151.8	115.3	152	-173.2	0	0	0	0	110
31	G	40.6	Very low	37.8	Very low	61 Å²	61	130.1 Å²	130.1	63%	0.629	75%	0.753	S	S	*	*	S	Bend	trans	96.1	32	138.6	0	0	0	0	0	119.9
32	Q	38.4	Very low	38.9	Very low	145 Å²	145	128.5 Å²	128.5	68%	0.678	75%	0.751	S	S	*	*			trans	-113.2	11.4	175.4	-144.1	173.7	15	0	0	115.9
33	E	38.5	Very low	40.1	Very low	172 Å²	172	131.6 Å²	131.6	80%	0.804	74%	0.743	S	S	*	*	S	Bend	trans	-87.5	-32.9	172.5	-66.6	-173	147.1	0	0	112.7	M36 E37	E33-M36 PolarHBondContact O-N 3.18Å; E33-E37 PolarHBondContact O-N 3.35Å
34	G	42.1	Very low	41.4	Very low	51 Å²	51	132.8 Å²	132.8	53%	0.526	75%	0.745	S	S	.	*	H	α-helix	trans	-66.5	-40.1	-177.3	0	0	0	0	0	114.9	M36 E38	G34-M36 VanDerWaalsContact C-N 3.33Å; G34-M36 PolarHBondContact O-N 3.06Å; G34-E38 PolarHBondContact O-N 2.94Å
35	E	39.2	Very low	42.8	Very low	147 Å²	147	137.3 Å²	137.3	69%	0.687	75%	0.75	S	S	*	*	H	α-helix	trans	-75.3	-20.6	-178.4	-66.2	-172	152	0	0	113.2
36	M	39.5	Very low	44.4	Very low	116 Å²	116	138 Å²	138	57%	0.571	74%	0.736	S	S	*	*	H	α-helix	trans	-83.4	-33.4	175.6	-108.6	-179.6	-73.6	0	0	112.5	E33 G34 L40	E33-M36 PolarHBondContact O-N 3.18Å; G34-M36 VanDerWaalsContact C-N 3.33Å; G34-M36 PolarHBondContact O-N 3.06Å; M36-L40 WeakPolarHBondContact O-CB 3.28Å; M36-L40 WeakPolarHBondContact O-CG 3.47Å; M36-L40 PolarHBondContact O-N 3.43Å
37	E	43.3	Very low	46.8	Very low	155 Å²	155	132.8 Å²	132.8	72%	0.724	71%	0.714	S	S	*	*	H	α-helix	trans	-70.5	-34.8	170.7	-71.1	-164	140.7	0	0	112.4	E33 F39 L40 G41	E33-E37 PolarHBondContact O-N 3.35Å; E37-F39 VanDerWaalsContact C-N 3.26Å; E37-F39 PolarHBondContact O-N 3.43Å; E37-L40 PolarHBondContact O-N 2.91Å; E37-G41 PolarHBondContact O-N 3.39Å
38	E	45.8	Very low	48.8	Very low	172 Å²	172	131.8 Å²	131.8	80%	0.804	71%	0.705	S	S	*	*	H	α-helix	trans	-67.5	-25.5	177.7	-166.8	167.4	-165.2	0	0	113	G34	G34-E38 PolarHBondContact O-N 2.94Å
39	F	44.8	Very low	51.2	Low	192 Å²	192	127.8 Å²	127.8	84%	0.842	68%	0.682	S	S	*	*	H	α-helix	trans	-88.7	-17	174.7	-145.9	-91.5	0	0	0	114.1	E37	E37-F39 VanDerWaalsContact C-N 3.26Å; E37-F39 PolarHBondContact O-N 3.43Å
40	L	50.1	Low	53.2	Low	143 Å²	143	125.3 Å²	125.3	75%	0.749	67%	0.665	S	S	*	*	H	α-helix	trans	-109.3	-4.2	-179.7	-71	172.9	0	0	0	114.2	M36 E37	M36-L40 WeakPolarHBondContact O-CB 3.28Å; M36-L40 WeakPolarHBondContact O-CG 3.47Å; M36-L40 PolarHBondContact O-N 3.43Å; E37-L40 PolarHBondContact O-N 2.91Å
41	G	46.5	Very low	55.4	Low	40 Å²	40	121.7 Å²	121.7	41%	0.412	64%	0.64	S	S	.	*	S	Bend	trans	-54.4	139	172.4	0	0	0	0	0	111.1	E37 Q43	E37-G41 PolarHBondContact O-N 3.39Å; G41-Q43 PolarHBondContact O-N 3.1Å
42	P	53.7	Low	57.5	Low	126 Å²	126	123 Å²	123	82%	0.818	63%	0.63	S	S	*	*			trans	-57.1	120.5	178.8	24.3	-33.4	0	0	0	108.3	A44	P42-A44 PolarHBondContact O-N 3.28Å
43	Q	50.5	Low	59.8	Low	150 Å²	150	123 Å²	123	70%	0.701	62%	0.623	S	S	*	*			trans	-47.9	106.8	-177	-72.4	175.2	-16	0	0	109	G41 Q45 Y46	G41-Q43 PolarHBondContact O-N 3.1Å; Q43-Q45 PolarHBondContact O-N 3.1Å; Q43-Y46 PolarHBondContact O-N 3.06Å
44	A	54.8	Low	62.1	Low	109 Å²	109	118.7 Å²	118.7	90%	0.901	60%	0.602	S	S	*	*	T	Hydrogen-bonded Turn	trans	-69.5	12.7	-165.7	0	0	0	0	0	114.7	P42	P42-A44 PolarHBondContact O-N 3.28Å
45	Q	58.2	Low	64.4	Low	190 Å²	190	121.7 Å²	121.7	89%	0.888	60%	0.598	S	S	*	*	T	Hydrogen-bonded Turn	trans	-132.5	1.3	175	-65.1	-178.3	-7.8	0	0	112.9	Q43 N47	Q43-Q45 PolarHBondContact O-N 3.1Å; Q45-N47 PolarHBondContact O-N 3.36Å
46	Y	64	Low	66.7	Low	131 Å²	131	117.7 Å²	117.7	51%	0.514	58%	0.577	S	S	.	*			trans	-79.8	86.6	176.1	-171.6	-108.1	0	0	0	110.4	Q43 E48 E51	Q43-Y46 PolarHBondContact O-N 3.06Å; Y46-E48 HydrophobicContact CD1-CG 3.83Å; Y46-E48 HydrophobicContact CE1-CG 3.55Å; Y46-E48 PolarHBondContact O-N 2.97Å; Y46-E51 HydrophobicContact CD2-CG 4.49Å; Y46-E51 HydrophobicContact CE2-CB 4.42Å; Y46-E51 HydrophobicContact CE2-CG 3.91Å
47	N	81.1	Confident	69.1	Low	86 Å²	86	120.5 Å²	120.5	46%	0.46	58%	0.581	S	S	.	*			trans	-82.4	95.6	174.9	-174.2	-2.7	0	0	0	109.9	Q45 E49 E50 E51	Q45-N47 PolarHBondContact O-N 3.36Å; N47-E49 VanDerWaalsContact C-N 3.29Å; N47-E49 PolarHBondContact O-N 3.08Å; N47-E49 PolarHBondContact OD1-N 3.34Å; N47-E50 HydrophobicContact CB-CB 3.91Å; N47-E50 WeakPolarHBondContact O-CA 3.42Å; N47-E50 WeakPolarHBondContact O-CB 3.47Å; N47-E50 PolarHBondContact O-N 3.14Å; N47-E51 PolarHBondContact O-N 3.17Å
48	E	80.4	Confident	71.4	Confident	136 Å²	136	120.1 Å²	120.1	64%	0.636	57%	0.573	S	S	*	*	H	α-helix	trans	-50.1	-46.6	179.7	-71.4	-178.3	167	0	0	112.6	Y46 E50 E51 E52	Y46-E48 HydrophobicContact CD1-CG 3.83Å; Y46-E48 HydrophobicContact CE1-CG 3.55Å; Y46-E48 PolarHBondContact O-N 2.97Å; E48-E50 PolarHBondContact O-N 3.25Å; E48-E51 PolarHBondContact O-N 2.88Å; E48-E52 WeakPolarHBondContact O-CG 3.37Å; E48-E52 PolarHBondContact O-N 2.67Å
49	E	81.8	Confident	73.5	Confident	84 Å²	84	115.8 Å²	115.8	39%	0.393	55%	0.552	S	S	.	*	H	α-helix	trans	-58.7	-33.2	176.5	-84.2	-140.1	-132.7	0	0	113	N47 R53 K200	N47-E49 VanDerWaalsContact C-N 3.29Å; N47-E49 PolarHBondContact O-N 3.08Å; N47-E49 PolarHBondContact OD1-N 3.34Å; E49-R53 WeakPolarHBondContact O-CB 3.36Å; E49-R53 VanDerWaalsContact O-CD 3.29Å; E49-R53 WeakPolarHBondContact O-CD 3.31Å; E49-R53 WeakPolarHBondContact O-CG 3.43Å; E49-R53 PolarHBondContact O-N 3.4Å; E49-R53 VanDerWaalsContact O-N 3.09Å; E49-R53 PolarHBondContact O-NE 2.44Å; E49-R53 IonicContact OE2-CZ 2.87Å; E49-R53 IonicContact OE2-NE 2.7Å; E49-R53 IonicContact OE2-NH2 3.53Å; E49-R53 PolarHBondContact OE2-NH2 3.23Å; E49-K200 IonicContact OE2-NZ 2.37Å; E49-K200 PolarHBondContact OE2-NZ 2.92Å
50	E	83.6	Confident	75.7	Confident	91 Å²	91	111 Å²	111	43%	0.425	53%	0.528	S	S	.	.	H	α-helix	trans	-78.1	-40	179.8	-158.3	-170.7	126.8	0	0	111.7	N47 E48 R53 K54	N47-E50 HydrophobicContact CB-CB 3.91Å; N47-E50 WeakPolarHBondContact O-CA 3.42Å; N47-E50 WeakPolarHBondContact O-CB 3.47Å; N47-E50 PolarHBondContact O-N 3.14Å; E48-E50 PolarHBondContact O-N 3.25Å; E50-R53 PolarHBondContact O-N 2.96Å; E50-K54 WeakPolarHBondContact O-CB 3.46Å; E50-K54 WeakPolarHBondContact O-CD 3.5Å; E50-K54 VanDerWaalsContact O-CG 3.27Å; E50-K54 WeakPolarHBondContact O-CG 3.39Å; E50-K54 PolarHBondContact O-N 2.69Å; E50-K54 WeakPolarHBondContact OE1-CE 3.43Å; E50-K54 IonicContact OE1-NZ 2.77Å; E50-K54 PolarHBondContact OE1-NZ 2.66Å
51	E	85.9	Confident	77.7	Confident	59 Å²	59	109.2 Å²	109.2	28%	0.276	52%	0.519	S	S	.	.	H	α-helix	trans	-68.4	-36.5	174.1	-77.2	-52	132.3	0	0	112.7	Y46 N47 E48 K54 Y55 R58	Y46-E51 HydrophobicContact CD2-CG 4.49Å; Y46-E51 HydrophobicContact CE2-CB 4.42Å; Y46-E51 HydrophobicContact CE2-CG 3.91Å; N47-E51 PolarHBondContact O-N 3.17Å; E48-E51 PolarHBondContact O-N 2.88Å; E51-K54 CarbonylContact O-C 3.44Å; E51-K54 PolarHBondContact O-N 2.37Å; E51-K54 WeakPolarHBondContact OE1-CD 3.46Å; E51-K54 WeakPolarHBondContact OE1-CE 3.37Å; E51-K54 IonicContact OE1-NZ 3.58Å; E51-K54 PolarHBondContact OE1-NZ 2.64Å; E51-Y55 VanDerWaalsContact O-CB 3.29Å; E51-Y55 WeakPolarHBondContact O-CB 3.33Å; E51-Y55 PolarHBondContact O-N 3.17Å; E51-R58 IonicContact OE2-NH2 3.52Å; E51-R58 PolarHBondContact OE2-NH2 2.87Å
52	E	85.8	Confident	79.9	Confident	89 Å²	89	108.5 Å²	108.5	42%	0.416	51%	0.511	S	S	.	.	H	α-helix	trans	-58	-51	167.3	-77.3	-161	150.8	0	0	111.6	E48 K54 Y55 Y56	E48-E52 WeakPolarHBondContact O-CG 3.37Å; E48-E52 PolarHBondContact O-N 2.67Å; E52-K54 VanDerWaalsContact C-N 3.28Å; E52-K54 PolarHBondContact O-N 3.06Å; E52-Y55 WeakPolarHBondContact O-CA 3.17Å; E52-Y55 WeakPolarHBondContact O-CB 3.39Å; E52-Y55 PolarHBondContact O-N 3.12Å; E52-Y56 VanDerWaalsContact O-CD2 3.32Å; E52-Y56 WeakPolarHBondContact O-CD2 3.31Å; E52-Y56 PolarHBondContact O-N 2.86Å
53	R	85.3	Confident	81.8	Confident	144 Å²	144	102.8 Å²	102.8	54%	0.543	47%	0.474	S	S	.	.	H	α-helix	trans	-58.8	-41	178	-73	166.9	-160.1	-156.6	8.8	111	E49 E50 R57	E49-R53 WeakPolarHBondContact O-CB 3.36Å; E49-R53 VanDerWaalsContact O-CD 3.29Å; E49-R53 WeakPolarHBondContact O-CD 3.31Å; E49-R53 WeakPolarHBondContact O-CG 3.43Å; E49-R53 PolarHBondContact O-N 3.4Å; E49-R53 VanDerWaalsContact O-N 3.09Å; E49-R53 PolarHBondContact O-NE 2.44Å; E49-R53 IonicContact OE2-CZ 2.87Å; E49-R53 IonicContact OE2-NE 2.7Å; E49-R53 IonicContact OE2-NH2 3.53Å; E49-R53 PolarHBondContact OE2-NH2 3.23Å; E50-R53 PolarHBondContact O-N 2.96Å; R53-R57 WeakPolarHBondContact O-CB 3.35Å; R53-R57 PolarHBondContact O-N 3.27Å
54	K	88.8	Confident	83.9	Confident	81 Å²	81	99.2 Å²	99.2	35%	0.352	46%	0.459	S	S	.	.	H	α-helix	trans	-65.4	-38.2	173.4	-72.7	161.7	-176.4	164.5	0	111.9	E50 E51 E52 R58	E50-K54 WeakPolarHBondContact O-CB 3.46Å; E50-K54 WeakPolarHBondContact O-CD 3.5Å; E50-K54 VanDerWaalsContact O-CG 3.27Å; E50-K54 WeakPolarHBondContact O-CG 3.39Å; E50-K54 PolarHBondContact O-N 2.69Å; E50-K54 WeakPolarHBondContact OE1-CE 3.43Å; E50-K54 IonicContact OE1-NZ 2.77Å; E50-K54 PolarHBondContact OE1-NZ 2.66Å; E51-K54 CarbonylContact O-C 3.44Å; E51-K54 PolarHBondContact O-N 2.37Å; E51-K54 WeakPolarHBondContact OE1-CD 3.46Å; E51-K54 WeakPolarHBondContact OE1-CE 3.37Å; E51-K54 IonicContact OE1-NZ 3.58Å; E51-K54 PolarHBondContact OE1-NZ 2.64Å; E52-K54 VanDerWaalsContact C-N 3.28Å; E52-K54 PolarHBondContact O-N 3.06Å; K54-R58 WeakPolarHBondContact O-CB 3.38Å; K54-R58 VanDerWaalsContact O-CG 3.26Å; K54-R58 WeakPolarHBondContact O-CG 3.21Å; K54-R58 PolarHBondContact O-N 3.3Å; K54-R58 PolarHBondContact O-NE 2.86Å; K54-R58 VanDerWaalsContact O-NE 3.13Å
55	Y	89.3	Confident	85.8	Confident	115 Å²	115	99.3 Å²	99.3	45%	0.451	44%	0.439	S	S	.	.	H	α-helix	trans	-64.6	-53.9	176.8	-178.6	-88.2	0	0	0	111.5	E51 E52 R57 R58 K59	E51-Y55 VanDerWaalsContact O-CB 3.29Å; E51-Y55 WeakPolarHBondContact O-CB 3.33Å; E51-Y55 PolarHBondContact O-N 3.17Å; E52-Y55 WeakPolarHBondContact O-CA 3.17Å; E52-Y55 WeakPolarHBondContact O-CB 3.39Å; E52-Y55 PolarHBondContact O-N 3.12Å; Y55-R57 VanDerWaalsContact C-N 3.31Å; Y55-R57 PolarHBondContact O-N 2.99Å; Y55-R58 WeakPolarHBondContact O-CA 3.39Å; Y55-R58 WeakPolarHBondContact O-CB 3.5Å; Y55-R58 PolarHBondContact O-N 2.87Å; Y55-R58 VanDerWaalsContact O-N 3.09Å; Y55-K59 HydrophobicContact CD1-CG 4.09Å; Y55-K59 HydrophobicContact CE1-CD 4.33Å; Y55-K59 HydrophobicContact CE1-CG 3.79Å; Y55-K59 WeakPolarHBondContact O-CG 3.33Å; Y55-K59 PolarHBondContact O-N 2.7Å; Y55-K59 WeakPolarHBondContact OH-CE 3.36Å; Y55-K59 PolarHBondContact OH-NZ 3.24Å
56	Y	88.4	Confident	87.5	Confident	62 Å²	62	91.1 Å²	91.1	24%	0.243	40%	0.401	C	S	.	.	H	α-helix	trans	-64.7	-33.7	177.9	-75.3	-72.3	0	0	0	112.4	E52 K59 R60 Y196 Y199	E52-Y56 VanDerWaalsContact O-CD2 3.32Å; E52-Y56 WeakPolarHBondContact O-CD2 3.31Å; E52-Y56 PolarHBondContact O-N 2.86Å; Y56-K59 PolarHBondContact O-N 2.88Å; Y56-R60 WeakPolarHBondContact O-CB 3.36Å; Y56-R60 WeakPolarHBondContact O-CG 3.31Å; Y56-R60 PolarHBondContact O-N 3.18Å; Y56-Y196 AromaticContact CD1-CD1 3.94Å; Y56-Y196 HydrophobicContact CD1-CD1 3.94Å; Y56-Y196 HydrophobicContact CD1-CG 4.42Å; Y56-Y196 AromaticContact CE1-CD1 3.96Å; Y56-Y196 HydrophobicContact CE1-CD1 3.96Å; Y56-Y199 HydrophobicContact CD1-CD1 4.3Å; Y56-Y199 HydrophobicContact CD1-CG 4.07Å; Y56-Y199 AromaticContact CD2-CD1 3.75Å; Y56-Y199 HydrophobicContact CD2-CD1 3.75Å; Y56-Y199 AromaticContact CD2-CD2 3.61Å; Y56-Y199 HydrophobicContact CD2-CD2 3.61Å; Y56-Y199 AromaticContact CD2-CE1 3.87Å; Y56-Y199 HydrophobicContact CD2-CE1 3.87Å; Y56-Y199 AromaticContact CD2-CE2 3.7Å; Y56-Y199 HydrophobicContact CD2-CE2 3.7Å; Y56-Y199 AromaticContact CD2-CG 3.61Å; Y56-Y199 HydrophobicContact CD2-CG 3.61Å; Y56-Y199 AromaticContact CD2-CZ 3.82Å; Y56-Y199 HydrophobicContact CE1-CD2 4.4Å; Y56-Y199 HydrophobicContact CE1-CG 4.01Å; Y56-Y199 HydrophobicContact CE2-CD1 4.19Å; Y56-Y199 AromaticContact CE2-CD2 3.22Å; Y56-Y199 HydrophobicContact CE2-CD2 3.22Å; Y56-Y199 HydrophobicContact CE2-CE1 4.48Å; Y56-Y199 AromaticContact CE2-CE2 3.56Å; Y56-Y199 HydrophobicContact CE2-CE2 3.56Å; Y56-Y199 AromaticContact CE2-CG 3.55Å; Y56-Y199 HydrophobicContact CE2-CG 3.55Å; Y56-Y199 AromaticContact CG-CD1 3.82Å; Y56-Y199 HydrophobicContact CG-CD1 3.82Å; Y56-Y199 HydrophobicContact CG-CD2 4.35Å; Y56-Y199 HydrophobicContact CG-CE1 4.21Å; Y56-Y199 AromaticContact CG-CG 3.88Å; Y56-Y199 HydrophobicContact CG-CG 3.88Å; Y56-Y199 AromaticContact CZ-CD2 3.67Å; Y56-Y199 AromaticContact CZ-CG 3.75Å
57	R	89	Confident	89	Confident	176 Å²	176	85.1 Å²	85.1	66%	0.664	38%	0.379	S	S	*	.	H	α-helix	trans	-61.8	-44.4	169.8	-174.8	178.1	179.7	-172.4	-0.4	112.1	R53 Y55 R60 L61	R53-R57 WeakPolarHBondContact O-CB 3.35Å; R53-R57 PolarHBondContact O-N 3.27Å; Y55-R57 VanDerWaalsContact C-N 3.31Å; Y55-R57 PolarHBondContact O-N 2.99Å; R57-R60 PolarHBondContact O-N 3.48Å; R57-L61 HydrophobicContact CG-CD1 4.38Å; R57-L61 WeakPolarHBondContact O-CG 3.5Å; R57-L61 PolarHBondContact O-N 3.47Å
58	R	91.8	Very high	89.7	Confident	147 Å²	147	82.7 Å²	82.7	56%	0.555	37%	0.37	S	S	*	.	H	α-helix	trans	-61.1	-44.3	174.1	-77.1	176	-78.8	-169.4	-6.8	111.4	E51 K54 Y55 L61 G62	E51-R58 IonicContact OE2-NH2 3.52Å; E51-R58 PolarHBondContact OE2-NH2 2.87Å; K54-R58 WeakPolarHBondContact O-CB 3.38Å; K54-R58 VanDerWaalsContact O-CG 3.26Å; K54-R58 WeakPolarHBondContact O-CG 3.21Å; K54-R58 PolarHBondContact O-N 3.3Å; K54-R58 PolarHBondContact O-NE 2.86Å; K54-R58 VanDerWaalsContact O-NE 3.13Å; Y55-R58 WeakPolarHBondContact O-CA 3.39Å; Y55-R58 WeakPolarHBondContact O-CB 3.5Å; Y55-R58 PolarHBondContact O-N 2.87Å; Y55-R58 VanDerWaalsContact O-N 3.09Å; R58-L61 PolarHBondContact O-N 3.18Å; R58-G62 PolarHBondContact O-N 3.19Å
59	K	90.1	Very high	90.4	Very high	80 Å²	80	76.5 Å²	76.5	35%	0.348	34%	0.343	S	S	.	.	H	α-helix	trans	-62	-47.2	176.1	-68.9	-71.2	-174.5	172.2	0	112.5	Y55 Y56 L61 G62 V63 Y196	Y55-K59 HydrophobicContact CD1-CG 4.09Å; Y55-K59 HydrophobicContact CE1-CD 4.33Å; Y55-K59 HydrophobicContact CE1-CG 3.79Å; Y55-K59 WeakPolarHBondContact O-CG 3.33Å; Y55-K59 PolarHBondContact O-N 2.7Å; Y55-K59 WeakPolarHBondContact OH-CE 3.36Å; Y55-K59 PolarHBondContact OH-NZ 3.24Å; Y56-K59 PolarHBondContact O-N 2.88Å; K59-L61 PolarHBondContact O-N 3.35Å; K59-G62 CarbonylContact O-C 3.58Å; K59-G62 WeakPolarHBondContact O-CA 3.34Å; K59-G62 PolarHBondContact O-N 3.42Å; K59-V63 PolarHBondContact O-N 2.93Å; K59-Y196 HydrophobicContact CB-CD2 3.95Å; K59-Y196 HydrophobicContact CB-CE2 4.07Å; K59-Y196 HydrophobicContact CB-CG 4.21Å
60	R	91.3	Very high	91.1	Very high	93 Å²	93	72.5 Å²	72.5	35%	0.351	32%	0.324	S	S	.	.	H	α-helix	trans	-58.7	-43.7	176.1	-78.9	174.5	56.1	-157.9	-7.4	112.7	Y56 R57 G62 V63 I64 Y193	Y56-R60 WeakPolarHBondContact O-CB 3.36Å; Y56-R60 WeakPolarHBondContact O-CG 3.31Å; Y56-R60 PolarHBondContact O-N 3.18Å; R57-R60 PolarHBondContact O-N 3.48Å; R60-G62 VanDerWaalsContact C-N 3.32Å; R60-V63 PolarHBondContact O-N 3.4Å; R60-I64 WeakPolarHBondContact O-CG1 3.4Å; R60-I64 PolarHBondContact O-N 2.92Å; R60-Y193 HydrophobicContact CB-CD2 4.21Å; R60-Y193 HydrophobicContact CB-CE2 3.75Å; R60-Y193 HydrophobicContact CG-CD2 4.1Å; R60-Y193 HydrophobicContact CG-CE2 3.87Å; R60-Y193 PolarHBondContact NE-OH 2.82Å; R60-Y193 PolarHBondContact NH2-OH 3.37Å
61	L	92.1	Very high	91.7	Very high	105 Å²	105	68.2 Å²	68.2	55%	0.55	30%	0.304	S	S	.	.	H	α-helix	trans	-63.6	-38.4	173.3	-74	168.2	0	0	0	111.8	R57 R58 K59 I64 K65	R57-L61 HydrophobicContact CG-CD1 4.38Å; R57-L61 WeakPolarHBondContact O-CG 3.5Å; R57-L61 PolarHBondContact O-N 3.47Å; R58-L61 PolarHBondContact O-N 3.18Å; K59-L61 PolarHBondContact O-N 3.35Å; L61-I64 PolarHBondContact O-N 3.48Å; L61-K65 WeakPolarHBondContact O-CB 3.3Å; L61-K65 PolarHBondContact O-N 2.93Å
62	G	92	Very high	92.2	Very high	25 Å²	25	70.1 Å²	70.1	26%	0.258	31%	0.311	S	S	.	.	H	α-helix	trans	-58.1	-45.6	171.7	0	0	0	0	0	113.1	R58 K59 R60 K65 N66	R58-G62 PolarHBondContact O-N 3.19Å; K59-G62 CarbonylContact O-C 3.58Å; K59-G62 WeakPolarHBondContact O-CA 3.34Å; K59-G62 PolarHBondContact O-N 3.42Å; R60-G62 VanDerWaalsContact C-N 3.32Å; G62-K65 WeakPolarHBondContact O-CB 3.2Å; G62-K65 PolarHBondContact O-N 3.15Å; G62-N66 PolarHBondContact O-N 3.46Å; G62-N66 PolarHBondContact O-ND2 2.84Å; G62-N66 PolarHBondContact O-OD1 2.72Å
63	V	93.3	Very high	92.7	Very high	5 Å²	5	65.9 Å²	65.9	3%	0.03	29%	0.291	C	S	.	.	H	α-helix	trans	-63.8	-44.6	176.6	174.3	0	0	0	0	111.7	K59 R60 K65 N66 V67 M189 Y193 Y196 F222	K59-V63 PolarHBondContact O-N 2.93Å; R60-V63 PolarHBondContact O-N 3.4Å; V63-K65 VanDerWaalsContact C-N 3.32Å; V63-K65 PolarHBondContact O-N 2.58Å; V63-N66 WeakPolarHBondContact O-CB 3.3Å; V63-N66 PolarHBondContact O-N 3.44Å; V63-V67 WeakPolarHBondContact O-CG2 3.28Å; V63-V67 PolarHBondContact O-N 2.76Å; V63-M189 HydrophobicContact CB-SD 4.5Å; V63-M189 HydrophobicContact CG1-CB 4.04Å; V63-M189 VanDerWaalsContact CG1-O 3.3Å; V63-M189 WeakPolarHBondContact CG1-O 3.48Å; V63-M189 HydrophobicContact CG1-SD 3.96Å; V63-M189 HydrophobicContact CG2-SD 4.41Å; V63-Y193 HydrophobicContact CB-CD2 4.41Å; V63-Y193 HydrophobicContact CG1-CD2 4.29Å; V63-Y196 HydrophobicContact CG2-CD2 3.91Å; V63-Y196 HydrophobicContact CG2-CE2 3.8Å; V63-F222 HydrophobicContact CG1-CE2 3.97Å
64	I	94.3	Very high	93.3	Very high	76 Å²	76	59 Å²	59	39%	0.39	27%	0.265	S	S	.	.	H	α-helix	trans	-60.5	-43.5	175.7	-66.6	167.5	0	0	0	110.7	R60 L61 N66 V67 A68 Y193 F222	R60-I64 WeakPolarHBondContact O-CG1 3.4Å; R60-I64 PolarHBondContact O-N 2.92Å; L61-I64 PolarHBondContact O-N 3.48Å; I64-N66 PolarHBondContact O-N 2.93Å; I64-V67 PolarHBondContact O-N 3.19Å; I64-A68 WeakPolarHBondContact O-CB 3.36Å; I64-A68 PolarHBondContact O-N 2.99Å; I64-Y193 HydrophobicContact CD1-CE2 3.75Å; I64-Y193 HydrophobicContact CG1-CD2 4.3Å; I64-Y193 HydrophobicContact CG1-CE2 3.89Å; I64-F222 HydrophobicContact CG1-CZ 4.45Å
65	K	94.8	Very high	93.7	Very high	111 Å²	111	55.9 Å²	55.9	48%	0.483	25%	0.252	S	S	.	.	H	α-helix	trans	-58.7	-44.8	174.7	-172.1	-161.1	70.7	168.9	0	111.6	L61 G62 V63 A68 A69	L61-K65 WeakPolarHBondContact O-CB 3.3Å; L61-K65 PolarHBondContact O-N 2.93Å; G62-K65 WeakPolarHBondContact O-CB 3.2Å; G62-K65 PolarHBondContact O-N 3.15Å; V63-K65 VanDerWaalsContact C-N 3.32Å; V63-K65 PolarHBondContact O-N 2.58Å; K65-A68 PolarHBondContact O-N 2.96Å; K65-A69 WeakPolarHBondContact O-CB 3.28Å; K65-A69 PolarHBondContact O-N 3.35Å
66	N	94.5	Very high	94.1	Very high	17 Å²	17	51.3 Å²	51.3	9%	0.091	24%	0.236	C	C	.	.	H	α-helix	trans	-62.3	-43.4	178.7	-66.5	-11.3	0	0	0	112.2	G62 V63 I64 A69 S70 Y185 M189 L308 G310	G62-N66 PolarHBondContact O-N 3.46Å; G62-N66 PolarHBondContact O-ND2 2.84Å; G62-N66 PolarHBondContact O-OD1 2.72Å; V63-N66 WeakPolarHBondContact O-CB 3.3Å; V63-N66 PolarHBondContact O-N 3.44Å; I64-N66 PolarHBondContact O-N 2.93Å; N66-A69 PolarHBondContact O-N 3.03Å; N66-S70 WeakPolarHBondContact O-CB 3.37Å; N66-S70 PolarHBondContact O-N 3.2Å; N66-S70 PolarHBondContact O-OG 3.28Å; N66-Y185 HydrophobicContact CB-CE1 4.46Å; N66-M189 HydrophobicContact CB-SD 3.82Å; N66-L308 PolarHBondContact OD1-O 2.62Å; N66-L308 VanDerWaalsContact OD1-O 3.13Å; N66-G310 PolarHBondContact OD1-N 2.83Å
67	V	95.1	Very high	94.5	Very high	6 Å²	6	48.6 Å²	48.6	4%	0.036	23%	0.225	C	C	.	.	H	α-helix	trans	-66.5	-44.9	177.8	171.2	0	0	0	0	110.9	V63 I64 S70 S71 I186 M189 F222	V63-V67 WeakPolarHBondContact O-CG2 3.28Å; V63-V67 PolarHBondContact O-N 2.76Å; I64-V67 PolarHBondContact O-N 3.19Å; V67-S70 WeakPolarHBondContact CA-OG 3.41Å; V67-S70 PolarHBondContact O-OG 2.98Å; V67-S70 VanDerWaalsContact O-OG 3.05Å; V67-S71 WeakPolarHBondContact O-CB 3.04Å; V67-S71 PolarHBondContact O-N 3.35Å; V67-S71 PolarHBondContact O-OG 3.31Å; V67-I186 HydrophobicContact CG1-CD1 4.08Å; V67-M189 HydrophobicContact CG2-CB 3.5Å; V67-M189 HydrophobicContact CG2-CG 4.04Å; V67-F222 HydrophobicContact CG1-CD2 4.4Å; V67-F222 HydrophobicContact CG1-CG 4.48Å; V67-F222 HydrophobicContact CG2-CD2 3.79Å; V67-F222 HydrophobicContact CG2-CE2 3.95Å
68	A	95.7	Very high	94.8	Very high	34 Å²	34	40.9 Å²	40.9	28%	0.281	20%	0.196	S	C	.	.	H	α-helix	trans	-61	-47.5	174.3	0	0	0	0	0	111.6	I64 K65 S71 F72	I64-A68 WeakPolarHBondContact O-CB 3.36Å; I64-A68 PolarHBondContact O-N 2.99Å; K65-A68 PolarHBondContact O-N 2.96Å; A68-S71 WeakPolarHBondContact O-CB 3.25Å; A68-S71 PolarHBondContact O-N 3.03Å; A68-F72 VanDerWaalsContact O-CD2 3.25Å; A68-F72 WeakPolarHBondContact O-CD2 3.4Å; A68-F72 PolarHBondContact O-N 2.65Å
69	A	95.8	Very high	95	Very high	7 Å²	7	34.5 Å²	34.5	6%	0.058	17%	0.174	C	C	.	.	H	α-helix	trans	-60.7	-47	179.7	0	0	0	0	0	112.7	K65 N66 S71 F72 G73 I304 L308	K65-A69 WeakPolarHBondContact O-CB 3.28Å; K65-A69 PolarHBondContact O-N 3.35Å; N66-A69 PolarHBondContact O-N 3.03Å; A69-S71 VanDerWaalsContact C-N 3.32Å; A69-S71 PolarHBondContact O-N 3.02Å; A69-F72 PolarHBondContact O-N 3.12Å; A69-G73 PolarHBondContact O-N 3.42Å; A69-I304 HydrophobicContact CB-CG2 4Å; A69-I304 WeakPolarHBondContact O-CG2 3.47Å; A69-L308 HydrophobicContact CB-CB 3.56Å; A69-L308 HydrophobicContact CB-CD2 4.22Å
70	S	95.6	Very high	95.3	Very high	0 Å²	0	31 Å²	31	0%	0	16%	0.159	C	C	.	.	H	α-helix	trans	-64.4	-35	175.8	49.5	0	0	0	0	112.7	N66 V67 A74 I186	N66-S70 WeakPolarHBondContact O-CB 3.37Å; N66-S70 PolarHBondContact O-N 3.2Å; N66-S70 PolarHBondContact O-OG 3.28Å; V67-S70 WeakPolarHBondContact CA-OG 3.41Å; V67-S70 PolarHBondContact O-OG 2.98Å; V67-S70 VanDerWaalsContact O-OG 3.05Å; S70-A74 VanDerWaalsContact O-CB 3.3Å; S70-A74 WeakPolarHBondContact O-CB 3.29Å; S70-A74 PolarHBondContact O-N 3.33Å; S70-I186 WeakPolarHBondContact OG-CD1 3.44Å
71	S	96.8	Very high	95.5	Very high	0 Å²	0	27.2 Å²	27.2	0%	0	15%	0.145	C	C	.	.	H	α-helix	trans	-64.9	-47.8	174.1	-53.7	0	0	0	0	112	V67 A68 A69 A74 M75 F226	V67-S71 WeakPolarHBondContact O-CB 3.04Å; V67-S71 PolarHBondContact O-N 3.35Å; V67-S71 PolarHBondContact O-OG 3.31Å; A68-S71 WeakPolarHBondContact O-CB 3.25Å; A68-S71 PolarHBondContact O-N 3.03Å; A69-S71 VanDerWaalsContact C-N 3.32Å; A69-S71 PolarHBondContact O-N 3.02Å; S71-A74 PolarHBondContact O-N 3.43Å; S71-M75 WeakPolarHBondContact O-CB 3.08Å; S71-M75 PolarHBondContact O-N 3.4Å; S71-F226 WeakPolarHBondContact OG-CD2 3.49Å
72	F	96.8	Very high	95.6	Very high	99 Å²	99	23.1 Å²	23.1	43%	0.434	12%	0.123	S	C	.	.	H	α-helix	trans	-66.2	-40.7	175.9	-81.4	-68.5	0	0	0	112.4	A68 A69 A74 M75 I76 I229	A68-F72 VanDerWaalsContact O-CD2 3.25Å; A68-F72 WeakPolarHBondContact O-CD2 3.4Å; A68-F72 PolarHBondContact O-N 2.65Å; A69-F72 PolarHBondContact O-N 3.12Å; F72-A74 PolarHBondContact O-N 3.05Å; F72-M75 HydrophobicContact CD1-CE 3.87Å; F72-M75 HydrophobicContact CD1-SD 4.35Å; F72-M75 HydrophobicContact CE1-CE 4.37Å; F72-M75 WeakPolarHBondContact O-CB 3.4Å; F72-M75 PolarHBondContact O-N 3.03Å; F72-I76 VanDerWaalsContact O-CG1 3.28Å; F72-I76 WeakPolarHBondContact O-CG1 3.43Å; F72-I76 PolarHBondContact O-N 3Å; F72-I229 HydrophobicContact CD1-CG2 3.98Å; F72-I229 HydrophobicContact CE1-CG2 4.12Å; F72-I229 HydrophobicContact CE2-CD1 4.21Å; F72-I229 HydrophobicContact CG-CG2 4.23Å; F72-I229 HydrophobicContact CZ-CD1 4.46Å; F72-I229 HydrophobicContact CZ-CG2 4.5Å
73	G	96.7	Very high	95.7	Very high	0 Å²	0	22 Å²	22	0%	0	11%	0.112	C	C	.	.	H	α-helix	trans	-59.6	-46.2	174.6	0	0	0	0	0	112	A69 I76 V77 F305	A69-G73 PolarHBondContact O-N 3.42Å; G73-I76 PolarHBondContact O-N 3.24Å; G73-V77 WeakPolarHBondContact O-CG2 3.47Å; G73-V77 PolarHBondContact O-N 3.35Å; G73-F305 VanDerWaalsContact C-CZ 3.45Å
74	A	96.6	Very high	95.8	Very high	0 Å²	0	21.8 Å²	21.8	0%	0	11%	0.111	C	C	.	.	H	α-helix	trans	-65.5	-39.8	176.8	0	0	0	0	0	112.4	S70 S71 F72 I76 Y78 F178 L182 F226 F305	S70-A74 VanDerWaalsContact O-CB 3.3Å; S70-A74 WeakPolarHBondContact O-CB 3.29Å; S70-A74 PolarHBondContact O-N 3.33Å; S71-A74 PolarHBondContact O-N 3.43Å; F72-A74 PolarHBondContact O-N 3.05Å; A74-I76 PolarHBondContact O-N 3.24Å; A74-Y78 WeakPolarHBondContact O-CB 3.42Å; A74-Y78 PolarHBondContact O-N 3.36Å; A74-F178 HydrophobicContact CB-CZ 4.32Å; A74-L182 HydrophobicContact CB-CD1 4.2Å; A74-L182 HydrophobicContact CB-CD2 3.66Å; A74-F226 HydrophobicContact CB-CE2 4.15Å; A74-F305 HydrophobicContact CB-CZ 4.4Å
75	M	97.2	Very high	95.7	Very high	15 Å²	15	19.4 Å²	19.4	7%	0.074	10%	0.099	C	C	.	.	H	α-helix	trans	-57.7	-48.1	174.7	-176.1	-165.1	77.1	0	0	111.4	S71 F72 S79 I229 L232 S233 F236	S71-M75 WeakPolarHBondContact O-CB 3.08Å; S71-M75 PolarHBondContact O-N 3.4Å; F72-M75 HydrophobicContact CD1-CE 3.87Å; F72-M75 HydrophobicContact CD1-SD 4.35Å; F72-M75 HydrophobicContact CE1-CE 4.37Å; F72-M75 WeakPolarHBondContact O-CB 3.4Å; F72-M75 PolarHBondContact O-N 3.03Å; M75-S79 WeakPolarHBondContact O-CB 3.44Å; M75-S79 PolarHBondContact O-N 3.45Å; M75-S79 PolarHBondContact O-OG 3.1Å; M75-S79 VanDerWaalsContact O-OG 3.14Å; M75-I229 HydrophobicContact CB-CG2 4.21Å; M75-I229 WeakPolarHBondContact CG-O 3.24Å; M75-I229 HydrophobicContact SD-CG2 4.01Å; M75-L232 HydrophobicContact CG-CB 4.48Å; M75-L232 HydrophobicContact SD-CB 3.92Å; M75-S233 WeakPolarHBondContact O-CB 3.17Å; M75-F236 HydrophobicContact CE-CD2 4Å; M75-F236 HydrophobicContact CE-CE2 3.82Å; M75-F236 HydrophobicContact CG-CD2 4.44Å; M75-F236 HydrophobicContact SD-CD2 3.97Å; M75-F236 HydrophobicContact SD-CE2 3.77Å
76	I	97.6	Very high	95.6	Very high	20 Å²	20	15.4 Å²	15.4	10%	0.103	8%	0.082	C	C	.	.	H	α-helix	trans	-69.7	-45.3	-177.6	-62.8	163.3	0	0	0	111.7	F72 G73 A74 Y78 S79 V80 F297 A301 I304	F72-I76 VanDerWaalsContact O-CG1 3.28Å; F72-I76 WeakPolarHBondContact O-CG1 3.43Å; F72-I76 PolarHBondContact O-N 3Å; G73-I76 PolarHBondContact O-N 3.24Å; A74-I76 PolarHBondContact O-N 3.24Å; I76-Y78 VanDerWaalsContact C-N 3.29Å; I76-Y78 PolarHBondContact O-N 3.01Å; I76-S79 WeakPolarHBondContact CA-OG 3.45Å; I76-S79 PolarHBondContact O-N 3.17Å; I76-S79 PolarHBondContact O-OG 3.14Å; I76-V80 HydrophobicContact CG2-CG2 4.38Å; I76-V80 WeakPolarHBondContact O-CB 3.28Å; I76-V80 WeakPolarHBondContact O-CG2 3.19Å; I76-V80 PolarHBondContact O-N 3.24Å; I76-F297 HydrophobicContact CG2-CB 3.88Å; I76-F297 VanDerWaalsContact CG2-O 3.26Å; I76-F297 WeakPolarHBondContact CG2-O 3.42Å; I76-A301 HydrophobicContact CB-CB 3.93Å; I76-A301 HydrophobicContact CG2-CB 3.84Å; I76-I304 HydrophobicContact CD1-CD1 4.01Å
77	V	96.8	Very high	95.4	Very high	5 Å²	5	14.7 Å²	14.7	3%	0.03	8%	0.078	C	C	.	.	H	α-helix	trans	-56.5	-47.3	176.2	169	0	0	0	0	110.4	G73 Y81 Y149 F178 A301 F305	G73-V77 WeakPolarHBondContact O-CG2 3.47Å; G73-V77 PolarHBondContact O-N 3.35Å; V77-Y81 WeakPolarHBondContact O-CB 3.48Å; V77-Y81 PolarHBondContact O-N 3.07Å; V77-Y149 HydrophobicContact CG1-CD1 4.18Å; V77-Y149 HydrophobicContact CG1-CD2 3.6Å; V77-Y149 HydrophobicContact CG1-CE2 4.22Å; V77-Y149 HydrophobicContact CG1-CG 3.59Å; V77-F178 HydrophobicContact CG1-CZ 4.31Å; V77-A301 HydrophobicContact CG2-CB 3.68Å; V77-F305 HydrophobicContact CG2-CE2 4Å
78	Y	95.3	Very high	95.1	Very high	14 Å²	14	14.6 Å²	14.6	6%	0.055	8%	0.077	C	C	.	.	H	α-helix	trans	-73.9	-35.1	-175.9	-155.5	-104.5	0	0	0	112.8	A74 I76 Y81 M82 W179 F230 F234 M356	A74-Y78 WeakPolarHBondContact O-CB 3.42Å; A74-Y78 PolarHBondContact O-N 3.36Å; I76-Y78 VanDerWaalsContact C-N 3.29Å; I76-Y78 PolarHBondContact O-N 3.01Å; Y78-Y81 HydrophobicContact CD2-CD1 4.32Å; Y78-Y81 HydrophobicContact CE2-CD1 4.12Å; Y78-Y81 HydrophobicContact CE2-CE1 4.47Å; Y78-Y81 PolarHBondContact O-N 2.95Å; Y78-M82 HydrophobicContact CD1-CG 3.79Å; Y78-M82 HydrophobicContact CE1-CG 3.44Å; Y78-M82 VanDerWaalsContact CE1-CG 3.44Å; Y78-M82 HydrophobicContact CE1-SD 4.06Å; Y78-M82 HydrophobicContact CE2-CG 4.4Å; Y78-M82 HydrophobicContact CG-CG 4.4Å; Y78-M82 WeakPolarHBondContact O-CB 3.28Å; Y78-M82 WeakPolarHBondContact O-CG 3.3Å; Y78-M82 PolarHBondContact O-N 3.31Å; Y78-W179 HydrophobicContact CD2-CZ2 4.18Å; Y78-W179 HydrophobicContact CE2-CZ2 4.29Å; Y78-F230 AromaticContact CD1-CE2 3.7Å; Y78-F230 HydrophobicContact CD1-CE2 3.7Å; Y78-F230 AromaticContact CD1-CZ 3.6Å; Y78-F230 HydrophobicContact CD1-CZ 3.6Å; Y78-F230 HydrophobicContact CD2-CE2 4.43Å; Y78-F230 HydrophobicContact CE1-CE2 4.47Å; Y78-F230 AromaticContact CE1-CZ 3.95Å; Y78-F230 HydrophobicContact CE1-CZ 3.95Å; Y78-F230 AromaticContact CG-CE2 3.68Å; Y78-F230 HydrophobicContact CG-CE2 3.68Å; Y78-F230 AromaticContact CG-CZ 3.98Å; Y78-F230 HydrophobicContact CG-CZ 3.98Å; Y78-F234 AromaticContact CE1-CE1 3.79Å; Y78-F234 HydrophobicContact CE1-CE1 3.79Å; Y78-F234 AromaticContact CE1-CZ 3.93Å; Y78-F234 HydrophobicContact CE1-CZ 3.93Å; Y78-M356 HydrophobicContact CE1-CE 4.29Å; Y78-M356 WeakPolarHBondContact OH-CE 3.04Å
79	S	96.4	Very high	94.8	Very high	13 Å²	13	16.1 Å²	16.1	9%	0.091	8%	0.08	C	C	.	.	H	α-helix	trans	-65.1	-42.4	174.9	60.9	0	0	0	0	112	M75 I76 G83 S233 A237	M75-S79 WeakPolarHBondContact O-CB 3.44Å; M75-S79 PolarHBondContact O-N 3.45Å; M75-S79 PolarHBondContact O-OG 3.1Å; M75-S79 VanDerWaalsContact O-OG 3.14Å; I76-S79 WeakPolarHBondContact CA-OG 3.45Å; I76-S79 PolarHBondContact O-N 3.17Å; I76-S79 PolarHBondContact O-OG 3.14Å; S79-G83 PolarHBondContact O-N 3.33Å; S79-S233 VanDerWaalsContact CB-O 3.28Å; S79-S233 WeakPolarHBondContact CB-O 3.36Å; S79-A237 WeakPolarHBondContact O-CA 3.39Å
80	V	96.9	Very high	94.5	Very high	5 Å²	5	16.8 Å²	16.8	3%	0.03	8%	0.084	C	C	.	.	H	α-helix	trans	-65.4	-46.7	176.9	170.7	0	0	0	0	110.7	I76 L84 V153 L294 F297 A298	I76-V80 HydrophobicContact CG2-CG2 4.38Å; I76-V80 WeakPolarHBondContact O-CB 3.28Å; I76-V80 WeakPolarHBondContact O-CG2 3.19Å; I76-V80 PolarHBondContact O-N 3.24Å; V80-L84 VanDerWaalsContact O-CB 3.25Å; V80-L84 WeakPolarHBondContact O-CB 3.43Å; V80-L84 PolarHBondContact O-N 3.48Å; V80-V153 HydrophobicContact CG1-CG2 3.6Å; V80-L294 HydrophobicContact CB-CD2 4.48Å; V80-L294 HydrophobicContact CG1-CB 4.11Å; V80-L294 HydrophobicContact CG1-CD2 4.33Å; V80-L294 HydrophobicContact CG2-CD2 4.09Å; V80-F297 HydrophobicContact CG2-CB 3.81Å; V80-A298 HydrophobicContact CG1-CB 4.36Å
81	Y	95.5	Very high	94.3	Very high	14 Å²	14	16.8 Å²	16.8	6%	0.055	8%	0.084	C	C	.	.	H	α-helix	trans	-59.7	-51.3	178.7	170.5	-113	0	0	0	112.6	V77 Y78 L85 Y149 F152 I171	V77-Y81 WeakPolarHBondContact O-CB 3.48Å; V77-Y81 PolarHBondContact O-N 3.07Å; Y78-Y81 HydrophobicContact CD2-CD1 4.32Å; Y78-Y81 HydrophobicContact CE2-CD1 4.12Å; Y78-Y81 HydrophobicContact CE2-CE1 4.47Å; Y78-Y81 PolarHBondContact O-N 2.95Å; Y81-L85 HydrophobicContact CE2-CD1 3.95Å; Y81-L85 VanDerWaalsContact O-CB 3.26Å; Y81-L85 WeakPolarHBondContact O-CB 3.49Å; Y81-L85 PolarHBondContact O-N 3.08Å; Y81-Y149 AromaticContact CD1-CE1 3.99Å; Y81-Y149 HydrophobicContact CD1-CE1 3.99Å; Y81-Y149 AromaticContact CD2-CD1 3.86Å; Y81-Y149 HydrophobicContact CD2-CD1 3.86Å; Y81-Y149 AromaticContact CD2-CE1 3.75Å; Y81-Y149 HydrophobicContact CD2-CE1 3.75Å; Y81-Y149 HydrophobicContact CE1-CE1 4.38Å; Y81-Y149 HydrophobicContact CE2-CE1 4.18Å; Y81-Y149 AromaticContact CG-CD1 3.89Å; Y81-Y149 HydrophobicContact CG-CD1 3.89Å; Y81-Y149 AromaticContact CG-CE1 3.65Å; Y81-Y149 HydrophobicContact CG-CE1 3.65Å; Y81-F152 HydrophobicContact CD2-CD1 4.37Å; Y81-F152 HydrophobicContact CD2-CE1 4.31Å; Y81-F152 HydrophobicContact CE2-CE1 4.33Å; Y81-I171 HydrophobicContact CD2-CD1 3.88Å; Y81-I171 HydrophobicContact CE2-CD1 3.66Å; Y81-I171 HydrophobicContact CE2-CG2 4.3Å
82	M	94.3	Very high	93.9	Very high	19 Å²	19	17 Å²	17	9%	0.094	9%	0.085	C	C	.	.	H	α-helix	trans	-66.7	-44.2	-179	-72	-59.5	-56.6	0	0	112	Y78 L85 Q86 A237 I360	Y78-M82 HydrophobicContact CD1-CG 3.79Å; Y78-M82 HydrophobicContact CE1-CG 3.44Å; Y78-M82 VanDerWaalsContact CE1-CG 3.44Å; Y78-M82 HydrophobicContact CE1-SD 4.06Å; Y78-M82 HydrophobicContact CE2-CG 4.4Å; Y78-M82 HydrophobicContact CG-CG 4.4Å; Y78-M82 WeakPolarHBondContact O-CB 3.28Å; Y78-M82 WeakPolarHBondContact O-CG 3.3Å; Y78-M82 PolarHBondContact O-N 3.31Å; M82-L85 PolarHBondContact O-N 3.09Å; M82-Q86 VanDerWaalsContact O-CB 3.28Å; M82-Q86 WeakPolarHBondContact O-CB 3.45Å; M82-Q86 PolarHBondContact O-N 3.24Å; M82-A237 HydrophobicContact CB-CB 3.81Å; M82-I360 HydrophobicContact CE-CD1 4.21Å; M82-I360 HydrophobicContact CE-CG2 3.93Å
83	G	94.4	Very high	93.4	Very high	2 Å²	2	16.3 Å²	16.3	2%	0.021	8%	0.08	C	C	.	.	H	α-helix	trans	-65.2	-40.6	-179.3	0	0	0	0	0	113.1	S79 M87 A237	S79-G83 PolarHBondContact O-N 3.33Å; G83-M87 VanDerWaalsContact O-CB 3.31Å; G83-M87 WeakPolarHBondContact O-CB 3.28Å; G83-M87 PolarHBondContact O-N 2.9Å; G83-A237 WeakPolarHBondContact CA-O 3.43Å
84	L	94.1	Very high	93	Very high	0 Å²	0	16.3 Å²	16.3	0%	0	8%	0.08	C	C	.	.	H	α-helix	trans	-64.3	-49	173.7	-179.4	63.6	0	0	0	111.4	V80 Q86 M87 Q88 F152 V153 N156 E291 L294	V80-L84 VanDerWaalsContact O-CB 3.25Å; V80-L84 WeakPolarHBondContact O-CB 3.43Å; V80-L84 PolarHBondContact O-N 3.48Å; L84-Q86 VanDerWaalsContact C-N 3.31Å; L84-Q86 PolarHBondContact O-N 3.22Å; L84-M87 HydrophobicContact CD1-CE 4.01Å; L84-M87 PolarHBondContact O-N 3.26Å; L84-Q88 HydrophobicContact CD1-CG 3.95Å; L84-Q88 HydrophobicContact CG-CG 4.32Å; L84-Q88 WeakPolarHBondContact O-CB 3.38Å; L84-Q88 VanDerWaalsContact O-CG 3.3Å; L84-Q88 WeakPolarHBondContact O-CG 3.48Å; L84-Q88 PolarHBondContact O-N 3.29Å; L84-F152 HydrophobicContact CD2-CD1 4.3Å; L84-F152 HydrophobicContact CD2-CE1 4.13Å; L84-V153 HydrophobicContact CD2-CB 4.11Å; L84-V153 HydrophobicContact CD2-CG1 4.11Å; L84-V153 HydrophobicContact CD2-CG2 3.89Å; L84-N156 HydrophobicContact CD1-CB 4.31Å; L84-N156 HydrophobicContact CD2-CB 4.11Å; L84-E291 HydrophobicContact CD1-CG 4.39Å; L84-L294 HydrophobicContact CB-CD1 4.48Å
85	L	92.4	Very high	92.5	Very high	26 Å²	26	19.4 Å²	19.4	14%	0.136	10%	0.095	C	C	.	.	H	α-helix	trans	-61.6	-39.6	-178.5	-174.6	149	0	0	0	111.6	Y81 M82 L89 I118	Y81-L85 HydrophobicContact CE2-CD1 3.95Å; Y81-L85 VanDerWaalsContact O-CB 3.26Å; Y81-L85 WeakPolarHBondContact O-CB 3.49Å; Y81-L85 PolarHBondContact O-N 3.08Å; M82-L85 PolarHBondContact O-N 3.09Å; L85-L89 HydrophobicContact CD2-CD1 3.59Å; L85-L89 HydrophobicContact CD2-CG 4.34Å; L85-L89 HydrophobicContact CG-CD1 4.41Å; L85-L89 WeakPolarHBondContact O-CB 3.27Å; L85-L89 VanDerWaalsContact O-CG 3.27Å; L85-L89 WeakPolarHBondContact O-CG 3.31Å; L85-L89 PolarHBondContact O-N 2.86Å; L85-I118 HydrophobicContact CD1-CD1 4.24Å
86	Q	92.4	Very high	92	Very high	27 Å²	27	21.4 Å²	21.4	13%	0.126	11%	0.108	C	C	.	.	H	α-helix	trans	-69.2	-41.8	175.9	179.7	173.1	-16.7	0	0	112.9	M82 L84 T90 E238	M82-Q86 VanDerWaalsContact O-CB 3.28Å; M82-Q86 WeakPolarHBondContact O-CB 3.45Å; M82-Q86 PolarHBondContact O-N 3.24Å; L84-Q86 VanDerWaalsContact C-N 3.31Å; L84-Q86 PolarHBondContact O-N 3.22Å; Q86-T90 WeakPolarHBondContact O-CB 3.34Å; Q86-T90 PolarHBondContact O-N 2.73Å; Q86-T90 VanDerWaalsContact O-N 3.08Å; Q86-T90 PolarHBondContact O-OG1 3.34Å; Q86-E238 PolarHBondContact NE2-OE1 3.42Å; Q86-E238 PolarHBondContact NE2-OE2 3.27Å; Q86-E238 PolarHBondContact OE1-OE1 3.09Å; Q86-E238 VanDerWaalsContact OE1-OE1 3.09Å
87	M	90.7	Very high	91.5	Very high	3 Å²	3	20.8 Å²	20.8	2%	0.015	10%	0.104	C	C	.	.	H	α-helix	trans	-61.6	-48.9	175.7	-176	179.5	75.6	0	0	111	G83 L84 T90 L91 P240 L287 V290 E291	G83-M87 VanDerWaalsContact O-CB 3.31Å; G83-M87 WeakPolarHBondContact O-CB 3.28Å; G83-M87 PolarHBondContact O-N 2.9Å; L84-M87 HydrophobicContact CD1-CE 4.01Å; L84-M87 PolarHBondContact O-N 3.26Å; M87-T90 PolarHBondContact O-N 2.84Å; M87-L91 HydrophobicContact CG-CD1 3.98Å; M87-L91 WeakPolarHBondContact O-CG 3.44Å; M87-L91 PolarHBondContact O-N 3.33Å; M87-P240 HydrophobicContact SD-CB 4.32Å; M87-L287 HydrophobicContact CE-CD1 3.88Å; M87-L287 HydrophobicContact SD-CD1 3.9Å; M87-V290 HydrophobicContact SD-CG1 4.34Å; M87-E291 HydrophobicContact CE-CG 4.01Å
88	Q	90.1	Very high	91.1	Very high	3 Å²	3	22.1 Å²	22.1	1%	0.014	11%	0.109	C	C	.	.	H	α-helix	trans	-61.8	-53.1	-179.9	-72.7	-72.3	-10.3	0	0	111.1	L84 T90 L91 H92 E159 E291	L84-Q88 HydrophobicContact CD1-CG 3.95Å; L84-Q88 HydrophobicContact CG-CG 4.32Å; L84-Q88 WeakPolarHBondContact O-CB 3.38Å; L84-Q88 VanDerWaalsContact O-CG 3.3Å; L84-Q88 WeakPolarHBondContact O-CG 3.48Å; L84-Q88 PolarHBondContact O-N 3.29Å; Q88-T90 PolarHBondContact O-N 3.04Å; Q88-T90 VanDerWaalsContact O-N 3.14Å; Q88-L91 PolarHBondContact O-N 3.24Å; Q88-H92 PolarHBondContact O-N 3.07Å; Q88-H92 PolarHBondContact O-ND1 3.34Å; Q88-H92 PolarHBondContact OE1-CE1 3.12Å; Q88-H92 PolarHBondContact OE1-NE2 3.03Å; Q88-E159 PolarHBondContact NE2-OE1 3.07Å; Q88-E159 VanDerWaalsContact NE2-OE1 3.13Å; Q88-E159 VanDerWaalsContact OE1-CD 3.3Å; Q88-E159 PolarHBondContact OE1-OE1 2.72Å; Q88-E159 PolarHBondContact OE1-OE2 2.84Å; Q88-E291 PolarHBondContact NE2-OE1 3.4Å
89	L	89.4	Confident	90.7	Very high	66 Å²	66	27 Å²	27	35%	0.346	13%	0.132	S	C	.	.	H	α-helix	trans	-57.4	-32.5	176.2	-72.5	179.5	0	0	0	113.7	L85 Y93	L85-L89 HydrophobicContact CD2-CD1 3.59Å; L85-L89 HydrophobicContact CD2-CG 4.34Å; L85-L89 HydrophobicContact CG-CD1 4.41Å; L85-L89 WeakPolarHBondContact O-CB 3.27Å; L85-L89 VanDerWaalsContact O-CG 3.27Å; L85-L89 WeakPolarHBondContact O-CG 3.31Å; L85-L89 PolarHBondContact O-N 2.86Å; L89-Y93 WeakPolarHBondContact O-CB 3.45Å; L89-Y93 PolarHBondContact O-N 3.15Å
90	T	89.5	Confident	90.2	Very high	22 Å²	22	31.5 Å²	31.5	14%	0.135	16%	0.159	C	C	.	.	H	α-helix	trans	-75.1	-36.1	177.5	-52.4	0	0	0	0	112	Q86 M87 Q88 M241 L245 L249 I374	Q86-T90 WeakPolarHBondContact O-CB 3.34Å; Q86-T90 PolarHBondContact O-N 2.73Å; Q86-T90 VanDerWaalsContact O-N 3.08Å; Q86-T90 PolarHBondContact O-OG1 3.34Å; M87-T90 PolarHBondContact O-N 2.84Å; Q88-T90 PolarHBondContact O-N 3.04Å; Q88-T90 VanDerWaalsContact O-N 3.14Å; T90-M241 HydrophobicContact CG2-CE 4.32Å; T90-L245 HydrophobicContact CG2-CD2 3.57Å; T90-L249 HydrophobicContact CG2-CD2 4.33Å; T90-I374 HydrophobicContact CG2-CG2 4.14Å
91	L	89.7	Confident	89.6	Confident	0 Å²	0	35.7 Å²	35.7	0%	0	18%	0.177	C	C	.	.	H	α-helix	trans	-73.2	-43.1	177.3	-72.4	170.2	0	0	0	112.3	M87 Q88 Y93 D94 Y97 L245 L278 P282 L287	M87-L91 HydrophobicContact CG-CD1 3.98Å; M87-L91 WeakPolarHBondContact O-CG 3.44Å; M87-L91 PolarHBondContact O-N 3.33Å; Q88-L91 PolarHBondContact O-N 3.24Å; L91-Y93 VanDerWaalsContact C-N 3.27Å; L91-Y93 PolarHBondContact O-N 3.03Å; L91-D94 PolarHBondContact O-N 3.19Å; L91-Y97 HydrophobicContact CB-CD1 4.09Å; L91-Y97 HydrophobicContact CB-CE1 3.87Å; L91-Y97 HydrophobicContact CD2-CD2 4.31Å; L91-Y97 HydrophobicContact CD2-CE2 4.23Å; L91-Y97 WeakPolarHBondContact O-CD1 3.34Å; L91-L245 HydrophobicContact CD2-CD1 3.77Å; L91-L278 HydrophobicContact CD2-CD2 3.99Å; L91-P282 HydrophobicContact CD2-CG 4.02Å; L91-L287 HydrophobicContact CD1-CD1 3.73Å; L91-L287 HydrophobicContact CD1-CD2 4.17Å
92	H	88.8	Confident	88.9	Confident	4 Å²	4	36 Å²	36	2%	0.019	18%	0.178	C	C	.	.	H	α-helix	trans	-69.7	-24.4	-179.1	-59.1	151.4	0	0	0	113.7	Q88 D94 R98 L107 D111 E159	Q88-H92 PolarHBondContact O-N 3.07Å; Q88-H92 PolarHBondContact O-ND1 3.34Å; Q88-H92 PolarHBondContact OE1-CE1 3.12Å; Q88-H92 PolarHBondContact OE1-NE2 3.03Å; H92-D94 PolarHBondContact O-N 3.28Å; H92-R98 PolarHBondContact O-NE 3.39Å; H92-R98 PolarHBondContact O-NH2 3.24Å; H92-L107 HydrophobicContact CB-CD2 4.2Å; H92-L107 WeakPolarHBondContact CD2-CD2 3.24Å; H92-D111 VanDerWaalsContact CB-OD2 3.24Å; H92-D111 WeakPolarHBondContact CB-OD2 3.36Å; H92-D111 IonicContact CE1-OD1 2.63Å; H92-D111 IonicContact CG-OD1 3.36Å; H92-D111 IonicContact CG-OD2 2.68Å; H92-D111 IonicContact ND1-OD1 3.58Å; H92-D111 PolarHBondContact ND1-OD1 2.91Å; H92-D111 IonicContact ND1-OD2 3.62Å; H92-E159 IonicContact CD2-OE2 3.9Å; H92-E159 IonicContact CE1-OE2 2.71Å; H92-E159 IonicContact NE2-OE2 2.76Å; H92-E159 PolarHBondContact NE2-OE2 3.15Å
93	Y	87.6	Confident	88.3	Confident	85 Å²	85	38.8 Å²	38.8	33%	0.333	20%	0.199	S	C	.	.	H	α-helix	trans	-61.6	-32.8	174.2	-171.9	-91.8	0	0	0	112.6	L89 L91 R98 F273 V277	L89-Y93 WeakPolarHBondContact O-CB 3.45Å; L89-Y93 PolarHBondContact O-N 3.15Å; L91-Y93 VanDerWaalsContact C-N 3.27Å; L91-Y93 PolarHBondContact O-N 3.03Å; Y93-R98 PolarHBondContact O-NH2 2.97Å; Y93-F273 HydrophobicContact CD1-CE1 4.38Å; Y93-F273 AromaticContact CE1-CD1 3.55Å; Y93-F273 HydrophobicContact CE1-CD1 3.55Å; Y93-F273 AromaticContact CE1-CE1 3.66Å; Y93-F273 HydrophobicContact CE1-CE1 3.66Å; Y93-F273 AromaticContact CZ-CD1 3.69Å; Y93-F273 WeakPolarHBondContact OH-CD1 3.49Å; Y93-V277 HydrophobicContact CD1-CG2 3.64Å; Y93-V277 HydrophobicContact CE1-CG2 3.9Å
94	D	87.7	Confident	87.4	Confident	0 Å²	0	46.3 Å²	46.3	0%	0	24%	0.239	C	C	.	.			trans	-78.9	127.2	-175.7	-170.2	99.5	0	0	0	112.9	L91 H92 T96 Y97 R98 T276 V277 L278	L91-D94 PolarHBondContact O-N 3.19Å; H92-D94 PolarHBondContact O-N 3.28Å; D94-T96 PolarHBondContact O-N 3.17Å; D94-T96 WeakPolarHBondContact OD2-CA 3.08Å; D94-T96 WeakPolarHBondContact OD2-CB 3.37Å; D94-T96 PolarHBondContact OD2-N 3.14Å; D94-T96 PolarHBondContact OD2-OG1 3.14Å; D94-Y97 PolarHBondContact O-N 3.41Å; D94-Y97 PolarHBondContact OD2-N 3.02Å; D94-R98 WeakPolarHBondContact O-CB 3.02Å; D94-R98 PolarHBondContact O-N 3.43Å; D94-T276 WeakPolarHBondContact OD1-CA 3.22Å; D94-V277 PolarHBondContact OD1-N 2.59Å; D94-L278 HydrophobicContact CB-CD1 3.4Å; D94-L278 VanDerWaalsContact CB-CD1 3.4Å; D94-L278 PolarHBondContact OD1-N 3.08Å
95	M	86.1	Confident	86.4	Confident	64 Å²	64	49.4 Å²	49.4	32%	0.315	26%	0.256	S	S	.	.	H	α-helix	trans	-62.8	-38.1	-179.7	-68.3	-70.5	-73.3	0	0	113	R98 E99 S275	M95-R98 PolarHBondContact O-N 3.23Å; M95-R98 PolarHBondContact SD-NH1 3.3Å; M95-E99 WeakPolarHBondContact CE-OE1 3.33Å; M95-E99 WeakPolarHBondContact O-CB 3.15Å; M95-E99 WeakPolarHBondContact O-CG 3.32Å; M95-E99 PolarHBondContact O-N 3.48Å; M95-S275 PolarHBondContact N-O 3.02Å; M95-S275 VanDerWaalsContact N-O 3.13Å
96	T	87.1	Confident	85.7	Confident	58 Å²	58	50.3 Å²	50.3	36%	0.356	27%	0.271	S	S	.	.	H	α-helix	trans	-69.2	-40.5	-176.9	72.6	0	0	0	0	111.4	D94 R98 V100 T276	D94-T96 PolarHBondContact O-N 3.17Å; D94-T96 WeakPolarHBondContact OD2-CA 3.08Å; D94-T96 WeakPolarHBondContact OD2-CB 3.37Å; D94-T96 PolarHBondContact OD2-N 3.14Å; D94-T96 PolarHBondContact OD2-OG1 3.14Å; T96-R98 VanDerWaalsContact C-N 3.35Å; T96-V100 VanDerWaalsContact O-CB 3.25Å; T96-V100 WeakPolarHBondContact O-CB 3.41Å; T96-V100 VanDerWaalsContact O-CG2 3.24Å; T96-V100 WeakPolarHBondContact O-CG2 3.28Å; T96-V100 PolarHBondContact O-N 3.46Å; T96-T276 HydrophobicContact CG2-CG2 3.95Å
97	Y	87.3	Confident	85.1	Confident	6 Å²	6	49.2 Å²	49.2	2%	0.024	27%	0.266	C	S	.	.	H	α-helix	trans	-63.9	-43.1	175.6	-175.6	-95.8	0	0	0	111.3	L91 D94 K101 Y102 L281 P282 L287	L91-Y97 HydrophobicContact CB-CD1 4.09Å; L91-Y97 HydrophobicContact CB-CE1 3.87Å; L91-Y97 HydrophobicContact CD2-CD2 4.31Å; L91-Y97 HydrophobicContact CD2-CE2 4.23Å; L91-Y97 WeakPolarHBondContact O-CD1 3.34Å; D94-Y97 PolarHBondContact O-N 3.41Å; D94-Y97 PolarHBondContact OD2-N 3.02Å; Y97-K101 HydrophobicContact CE1-CD 3.98Å; Y97-K101 HydrophobicContact CE2-CD 3.88Å; Y97-K101 VanDerWaalsContact CZ-CD 3.47Å; Y97-K101 VanDerWaalsContact O-CB 3.24Å; Y97-K101 WeakPolarHBondContact O-CB 3.4Å; Y97-K101 PolarHBondContact O-N 3.12Å; Y97-K101 WeakPolarHBondContact OH-CD 3.32Å; Y97-K101 PolarHBondContact OH-NZ 3.13Å; Y97-Y102 AromaticContact CE1-CE2 3.96Å; Y97-Y102 HydrophobicContact CE1-CE2 3.96Å; Y97-L281 HydrophobicContact CD2-CD1 3.7Å; Y97-L281 HydrophobicContact CD2-CG 4.47Å; Y97-L281 HydrophobicContact CG-CD1 4.3Å; Y97-P282 HydrophobicContact CD2-CG 4.49Å; Y97-P282 HydrophobicContact CE2-CG 4.32Å; Y97-L287 VanDerWaalsContact OH-CD2 3.29Å; Y97-L287 WeakPolarHBondContact OH-CD2 3.32Å
98	R	87.2	Confident	84.6	Confident	33 Å²	33	55 Å²	55	13%	0.125	29%	0.293	C	S	.	.	I	π-helix	trans	-62.8	-53.1	178.6	-164.1	-172.3	-53.7	165.1	-0.3	112.5	H92 Y93 D94 M95 T96 Y102 S103 L107 E108	H92-R98 PolarHBondContact O-NE 3.39Å; H92-R98 PolarHBondContact O-NH2 3.24Å; Y93-R98 PolarHBondContact O-NH2 2.97Å; D94-R98 WeakPolarHBondContact O-CB 3.02Å; D94-R98 PolarHBondContact O-N 3.43Å; M95-R98 PolarHBondContact O-N 3.23Å; M95-R98 PolarHBondContact SD-NH1 3.3Å; T96-R98 VanDerWaalsContact C-N 3.35Å; R98-Y102 CarbonylContact O-C 3.58Å; R98-Y102 WeakPolarHBondContact O-CA 3.16Å; R98-Y102 WeakPolarHBondContact O-CB 3.24Å; R98-Y102 PolarHBondContact O-N 3.29Å; R98-S103 PolarHBondContact O-N 3.03Å; R98-L107 HydrophobicContact CG-CB 3.93Å; R98-L107 HydrophobicContact CG-CD2 4.31Å; R98-E108 IonicContact CZ-OE1 3.43Å; R98-E108 IonicContact NH1-OE1 3.81Å; R98-E108 PolarHBondContact NH1-OE1 3.48Å; R98-E108 IonicContact NH2-OE1 2.68Å; R98-E108 PolarHBondContact NH2-OE1 2.97Å
99	E	86.1	Confident	84.3	Confident	116 Å²	116	57.3 Å²	57.3	54%	0.542	31%	0.305	S	S	.	.	I	π-helix	trans	-68.7	-38.8	-176.8	-70.2	177.1	-176.8	0	0	112.3	M95 S103	M95-E99 WeakPolarHBondContact CE-OE1 3.33Å; M95-E99 WeakPolarHBondContact O-CB 3.15Å; M95-E99 WeakPolarHBondContact O-CG 3.32Å; M95-E99 PolarHBondContact O-N 3.48Å; E99-S103 WeakPolarHBondContact O-CA 3.44Å; E99-S103 PolarHBondContact O-N 3.26Å
100	V	87.4	Confident	84.2	Confident	109 Å²	109	54.7 Å²	54.7	66%	0.661	29%	0.291	S	S	*	.	I	π-helix	trans	-80	-45.2	-177.1	178	0	0	0	0	112.8	T96 L281	T96-V100 VanDerWaalsContact O-CB 3.25Å; T96-V100 WeakPolarHBondContact O-CB 3.41Å; T96-V100 VanDerWaalsContact O-CG2 3.24Å; T96-V100 WeakPolarHBondContact O-CG2 3.28Å; T96-V100 PolarHBondContact O-N 3.46Å; V100-L281 HydrophobicContact CG1-CD2 4.13Å
101	K	83.1	Confident	84.1	Confident	93 Å²	93	54.5 Å²	54.5	40%	0.404	29%	0.29	S	S	.	.	I	π-helix	trans	-80	-35.4	-178.2	-170.2	-178.7	175.1	-160.3	0	112.1	Y97 E159	Y97-K101 HydrophobicContact CE1-CD 3.98Å; Y97-K101 HydrophobicContact CE2-CD 3.88Å; Y97-K101 VanDerWaalsContact CZ-CD 3.47Å; Y97-K101 VanDerWaalsContact O-CB 3.24Å; Y97-K101 WeakPolarHBondContact O-CB 3.4Å; Y97-K101 PolarHBondContact O-N 3.12Å; Y97-K101 WeakPolarHBondContact OH-CD 3.32Å; Y97-K101 PolarHBondContact OH-NZ 3.13Å; K101-E159 IonicContact NZ-OE1 3.31Å; K101-E159 PolarHBondContact NZ-OE1 3.24Å
102	Y	82.4	Confident	84	Confident	20 Å²	20	61.9 Å²	61.9	8%	0.078	32%	0.317	C	S	.	.	I	π-helix	trans	-121.7	-13.7	-169.5	-65.5	-67.2	0	0	0	115.2	Y97 R98 N104 L105 L107 E159	Y97-Y102 AromaticContact CE1-CE2 3.96Å; Y97-Y102 HydrophobicContact CE1-CE2 3.96Å; R98-Y102 CarbonylContact O-C 3.58Å; R98-Y102 WeakPolarHBondContact O-CA 3.16Å; R98-Y102 WeakPolarHBondContact O-CB 3.24Å; R98-Y102 PolarHBondContact O-N 3.29Å; Y102-N104 PolarHBondContact O-N 3.44Å; Y102-L105 HydrophobicContact CD1-CD1 4.22Å; Y102-L105 WeakPolarHBondContact O-CB 3.42Å; Y102-L105 WeakPolarHBondContact O-CD1 3.31Å; Y102-L105 PolarHBondContact O-N 3.35Å; Y102-L105 VanDerWaalsContact O-N 3.12Å; Y102-L107 HydrophobicContact CD1-CD1 3.89Å; Y102-L107 HydrophobicContact CD2-CD1 3.58Å; Y102-L107 HydrophobicContact CD2-CD2 3.41Å; Y102-L107 VanDerWaalsContact CD2-CD2 3.41Å; Y102-L107 HydrophobicContact CD2-CG 4.16Å; Y102-L107 HydrophobicContact CE1-CD1 4.39Å; Y102-L107 HydrophobicContact CE2-CD1 4.05Å; Y102-L107 HydrophobicContact CE2-CD2 3.69Å; Y102-L107 HydrophobicContact CG-CD1 3.46Å; Y102-L107 VanDerWaalsContact CG-CD1 3.46Å; Y102-L107 HydrophobicContact CG-CD2 4.17Å; Y102-L107 HydrophobicContact CG-CG 4.48Å; Y102-E159 HydrophobicContact CE1-CB 4.43Å; Y102-E159 WeakPolarHBondContact CE2-OE2 3.14Å; Y102-E159 VanDerWaalsContact CZ-OE2 3.23Å; Y102-E159 WeakPolarHBondContact OH-CB 3.23Å; Y102-E159 PolarHBondContact OH-OE1 3.29Å; Y102-E159 VanDerWaalsContact OH-OE1 3.08Å; Y102-E159 PolarHBondContact OH-OE2 3.36Å
103	S	80.1	Confident	84	Confident	77 Å²	77	64.3 Å²	64.3	54%	0.538	33%	0.328	S	S	.	.	T	Hydrogen-bonded Turn	trans	49.4	-116.2	177.6	178.5	0	0	0	0	110.9	R98 E99 L105	R98-S103 PolarHBondContact O-N 3.03Å; E99-S103 WeakPolarHBondContact O-CA 3.44Å; E99-S103 PolarHBondContact O-N 3.26Å; S103-L105 VanDerWaalsContact C-N 3.35Å; S103-L105 PolarHBondContact O-N 3.49Å
104	N	75.3	Confident	84.2	Confident	160 Å²	160	60.5 Å²	60.5	86%	0.856	31%	0.313	S	S	*	.	T	Hydrogen-bonded Turn	trans	-86.7	12	-173.1	-62.1	-16.1	0	0	0	115.1	Y102 G106	Y102-N104 PolarHBondContact O-N 3.44Å; N104-G106 PolarHBondContact O-N 3.19Å; N104-G106 VanDerWaalsContact O-N 3.15Å
105	L	73.1	Confident	84.3	Confident	66 Å²	66	63 Å²	63	35%	0.346	33%	0.327	S	S	.	.	S	Bend	trans	-72.9	0.6	-173.4	-94.4	144.7	0	0	0	116.4	Y102 S103 L107 R160	Y102-L105 HydrophobicContact CD1-CD1 4.22Å; Y102-L105 WeakPolarHBondContact O-CB 3.42Å; Y102-L105 WeakPolarHBondContact O-CD1 3.31Å; Y102-L105 PolarHBondContact O-N 3.35Å; Y102-L105 VanDerWaalsContact O-N 3.12Å; S103-L105 VanDerWaalsContact C-N 3.35Å; S103-L105 PolarHBondContact O-N 3.49Å; L105-L107 PolarHBondContact O-N 3.13Å; L105-R160 VanDerWaalsContact CD1-NH1 3.35Å
106	G	78.9	Confident	84.5	Confident	44 Å²	44	64.3 Å²	64.3	45%	0.454	33%	0.333	S	S	.	.			trans	64.1	40.6	170.6	0	0	0	0	0	114.2	N104 E108 D109 I110	N104-G106 PolarHBondContact O-N 3.19Å; N104-G106 VanDerWaalsContact O-N 3.15Å; G106-E108 VanDerWaalsContact C-N 3.28Å; G106-E108 PolarHBondContact O-N 2.99Å; G106-E108 VanDerWaalsContact O-N 3.15Å; G106-D109 WeakPolarHBondContact O-CB 3.45Å; G106-D109 PolarHBondContact O-N 3.26Å; G106-I110 PolarHBondContact O-N 3.41Å
107	L	79.3	Confident	84.7	Confident	5 Å²	5	61.8 Å²	61.8	3%	0.026	32%	0.318	C	S	.	.	H	α-helix	trans	-50.1	-41.3	-171.7	-124.9	71.1	0	0	0	114.3	H92 R98 Y102 L105 D109 I110 D111	H92-L107 HydrophobicContact CB-CD2 4.2Å; H92-L107 WeakPolarHBondContact CD2-CD2 3.24Å; R98-L107 HydrophobicContact CG-CB 3.93Å; R98-L107 HydrophobicContact CG-CD2 4.31Å; Y102-L107 HydrophobicContact CD1-CD1 3.89Å; Y102-L107 HydrophobicContact CD2-CD1 3.58Å; Y102-L107 HydrophobicContact CD2-CD2 3.41Å; Y102-L107 VanDerWaalsContact CD2-CD2 3.41Å; Y102-L107 HydrophobicContact CD2-CG 4.16Å; Y102-L107 HydrophobicContact CE1-CD1 4.39Å; Y102-L107 HydrophobicContact CE2-CD1 4.05Å; Y102-L107 HydrophobicContact CE2-CD2 3.69Å; Y102-L107 HydrophobicContact CG-CD1 3.46Å; Y102-L107 VanDerWaalsContact CG-CD1 3.46Å; Y102-L107 HydrophobicContact CG-CD2 4.17Å; Y102-L107 HydrophobicContact CG-CG 4.48Å; L105-L107 PolarHBondContact O-N 3.13Å; L107-D109 PolarHBondContact O-N 3.45Å; L107-D109 VanDerWaalsContact O-N 3.14Å; L107-I110 HydrophobicContact CD1-CD1 4.35Å; L107-I110 CarbonylContact O-C 3.39Å; L107-I110 WeakPolarHBondContact O-CA 3.43Å; L107-I110 WeakPolarHBondContact O-CB 3.5Å; L107-I110 PolarHBondContact O-N 2.94Å; L107-D111 VanDerWaalsContact O-CG 3.31Å; L107-D111 PolarHBondContact O-N 3.27Å
108	E	79.9	Confident	84.9	Confident	124 Å²	124	61.8 Å²	61.8	58%	0.579	32%	0.319	S	S	*	.	H	α-helix	trans	-56.2	-33.2	177.6	-61.2	-174.4	151.7	0	0	113.3	R98 G106 R112	R98-E108 IonicContact CZ-OE1 3.43Å; R98-E108 IonicContact NH1-OE1 3.81Å; R98-E108 PolarHBondContact NH1-OE1 3.48Å; R98-E108 IonicContact NH2-OE1 2.68Å; R98-E108 PolarHBondContact NH2-OE1 2.97Å; G106-E108 VanDerWaalsContact C-N 3.28Å; G106-E108 PolarHBondContact O-N 2.99Å; G106-E108 VanDerWaalsContact O-N 3.15Å; E108-R112 WeakPolarHBondContact O-CB 3.3Å; E108-R112 PolarHBondContact O-N 3.35Å
109	D	85.3	Confident	85.1	Confident	52 Å²	52	61 Å²	61	28%	0.278	32%	0.317	S	S	.	.	H	α-helix	trans	-78.4	-31.3	175.8	-173.7	44.9	0	0	0	111.9	G106 L107 R112 K113	G106-D109 WeakPolarHBondContact O-CB 3.45Å; G106-D109 PolarHBondContact O-N 3.26Å; L107-D109 PolarHBondContact O-N 3.45Å; L107-D109 VanDerWaalsContact O-N 3.14Å; D109-R112 IonicContact OD1-CZ 2.7Å; D109-R112 IonicContact OD1-NE 3.23Å; D109-R112 PolarHBondContact OD1-NE 3.15Å; D109-R112 IonicContact OD1-NH2 3.38Å; D109-R112 PolarHBondContact OD1-NH2 2.94Å; D109-K113 VanDerWaalsContact O-CB 3.29Å; D109-K113 WeakPolarHBondContact O-CB 3.46Å; D109-K113 WeakPolarHBondContact O-CD 3.41Å; D109-K113 WeakPolarHBondContact O-CG 3.39Å; D109-K113 PolarHBondContact O-N 3.11Å; D109-K113 WeakPolarHBondContact OD1-CE 3.27Å; D109-K113 IonicContact OD1-NZ 3.9Å; D109-K113 VanDerWaalsContact OD2-CE 3.23Å; D109-K113 WeakPolarHBondContact OD2-CE 3.43Å; D109-K113 IonicContact OD2-NZ 3.98Å; D109-K113 PolarHBondContact OD2-NZ 2.98Å
110	I	86.1	Confident	85.4	Confident	10 Å²	10	58.2 Å²	58.2	5%	0.051	31%	0.308	C	S	.	.	H	α-helix	trans	-64.8	-50.2	171.4	-58.2	-177.3	0	0	0	109.5	G106 L107 R112 K113 M114 L164	G106-I110 PolarHBondContact O-N 3.41Å; L107-I110 HydrophobicContact CD1-CD1 4.35Å; L107-I110 CarbonylContact O-C 3.39Å; L107-I110 WeakPolarHBondContact O-CA 3.43Å; L107-I110 WeakPolarHBondContact O-CB 3.5Å; L107-I110 PolarHBondContact O-N 2.94Å; I110-R112 PolarHBondContact O-N 3.38Å; I110-K113 CarbonylContact O-C 3.58Å; I110-K113 PolarHBondContact O-N 2.72Å; I110-K113 VanDerWaalsContact O-N 3.16Å; I110-M114 WeakPolarHBondContact O-CB 3.45Å; I110-M114 PolarHBondContact O-N 2.9Å; I110-L164 HydrophobicContact CG2-CD2 3.94Å
111	D	86.6	Confident	85.7	Confident	19 Å²	19	54.2 Å²	54.2	10%	0.102	28%	0.284	C	S	.	.	H	α-helix	trans	-65.5	-41.8	-178.1	-57.2	-27.9	0	0	0	111.7	H92 L107 K113 M114 L115	H92-D111 VanDerWaalsContact CB-OD2 3.24Å; H92-D111 WeakPolarHBondContact CB-OD2 3.36Å; H92-D111 IonicContact CE1-OD1 2.63Å; H92-D111 IonicContact CG-OD1 3.36Å; H92-D111 IonicContact CG-OD2 2.68Å; H92-D111 IonicContact ND1-OD1 3.58Å; H92-D111 PolarHBondContact ND1-OD1 2.91Å; H92-D111 IonicContact ND1-OD2 3.62Å; L107-D111 VanDerWaalsContact O-CG 3.31Å; L107-D111 PolarHBondContact O-N 3.27Å; D111-K113 VanDerWaalsContact C-N 3.31Å; D111-K113 PolarHBondContact O-N 2.79Å; D111-M114 PolarHBondContact O-N 3.44Å; D111-L115 VanDerWaalsContact O-CB 3.3Å; D111-L115 WeakPolarHBondContact O-CB 3.39Å; D111-L115 PolarHBondContact O-N 3.36Å
112	R	88.1	Confident	86.1	Confident	154 Å²	154	50 Å²	50	58%	0.581	27%	0.266	S	S	*	.	H	α-helix	trans	-59.2	-42.5	173.3	-178.1	177.2	66.4	-178.8	1.9	111.5	E108 D109 I110 M116	E108-R112 WeakPolarHBondContact O-CB 3.3Å; E108-R112 PolarHBondContact O-N 3.35Å; D109-R112 IonicContact OD1-CZ 2.7Å; D109-R112 IonicContact OD1-NE 3.23Å; D109-R112 PolarHBondContact OD1-NE 3.15Å; D109-R112 IonicContact OD1-NH2 3.38Å; D109-R112 PolarHBondContact OD1-NH2 2.94Å; I110-R112 PolarHBondContact O-N 3.38Å; R112-M116 VanDerWaalsContact O-CB 3.22Å; R112-M116 WeakPolarHBondContact O-CB 3.36Å; R112-M116 PolarHBondContact O-N 3.44Å
113	K	90.1	Very high	86.5	Confident	56 Å²	56	51.9 Å²	51.9	24%	0.243	28%	0.277	C	S	.	.	H	α-helix	trans	-75.1	-33.2	178.6	-72.5	173	-177.5	162.9	0	112.9	D109 I110 D111 M116 G117 Y161 V165	D109-K113 VanDerWaalsContact O-CB 3.29Å; D109-K113 WeakPolarHBondContact O-CB 3.46Å; D109-K113 WeakPolarHBondContact O-CD 3.41Å; D109-K113 WeakPolarHBondContact O-CG 3.39Å; D109-K113 PolarHBondContact O-N 3.11Å; D109-K113 WeakPolarHBondContact OD1-CE 3.27Å; D109-K113 IonicContact OD1-NZ 3.9Å; D109-K113 VanDerWaalsContact OD2-CE 3.23Å; D109-K113 WeakPolarHBondContact OD2-CE 3.43Å; D109-K113 IonicContact OD2-NZ 3.98Å; D109-K113 PolarHBondContact OD2-NZ 2.98Å; I110-K113 CarbonylContact O-C 3.58Å; I110-K113 PolarHBondContact O-N 2.72Å; I110-K113 VanDerWaalsContact O-N 3.16Å; D111-K113 VanDerWaalsContact C-N 3.31Å; D111-K113 PolarHBondContact O-N 2.79Å; K113-M116 HydrophobicContact CG-CE 4.38Å; K113-G117 PolarHBondContact O-N 2.94Å; K113-Y161 HydrophobicContact CD-CE2 3.6Å; K113-V165 HydrophobicContact CB-CG2 4.14Å
114	M	91.8	Very high	86.9	Confident	4 Å²	4	53 Å²	53	2%	0.02	28%	0.276	C	S	.	.	H	α-helix	trans	-60	-52.8	169.7	175.7	-177.6	65.6	0	0	110.1	I110 D111 M116 G117 I118 F152 L164 A168	I110-M114 WeakPolarHBondContact O-CB 3.45Å; I110-M114 PolarHBondContact O-N 2.9Å; D111-M114 PolarHBondContact O-N 3.44Å; M114-M116 VanDerWaalsContact C-N 3.32Å; M114-M116 PolarHBondContact O-N 2.85Å; M114-G117 PolarHBondContact O-N 3.41Å; M114-G117 VanDerWaalsContact O-N 3.1Å; M114-I118 HydrophobicContact CG-CD1 4.05Å; M114-I118 WeakPolarHBondContact O-CG1 3.17Å; M114-I118 PolarHBondContact O-N 3.08Å; M114-F152 HydrophobicContact CG-CE2 4.42Å; M114-F152 HydrophobicContact SD-CE2 3.99Å; M114-F152 HydrophobicContact SD-CZ 3.93Å; M114-L164 HydrophobicContact CG-CG 4.4Å; M114-L164 HydrophobicContact SD-CD1 4.09Å; M114-L164 HydrophobicContact SD-CD2 3.77Å; M114-L164 HydrophobicContact SD-CG 3.88Å; M114-A168 HydrophobicContact CB-CB 4.26Å; M114-A168 HydrophobicContact CG-CB 3.73Å
115	L	89.6	Confident	87.3	Confident	54 Å²	54	45.4 Å²	45.4	28%	0.283	24%	0.235	S	C	.	.	H	α-helix	trans	-66.3	-34.4	-179.2	-163.3	64.5	0	0	0	111.9	D111 N119 Y489	D111-L115 VanDerWaalsContact O-CB 3.3Å; D111-L115 WeakPolarHBondContact O-CB 3.39Å; D111-L115 PolarHBondContact O-N 3.36Å; L115-N119 WeakPolarHBondContact O-CB 3.38Å; L115-N119 PolarHBondContact O-N 3.27Å; L115-N119 VanDerWaalsContact O-N 3.1Å; L115-N119 PolarHBondContact O-ND2 2.89Å; L115-Y489 HydrophobicContact CB-CE2 4.41Å; L115-Y489 HydrophobicContact CD2-CD2 4.1Å; L115-Y489 HydrophobicContact CD2-CE2 3.95Å; L115-Y489 HydrophobicContact CG-CD2 4.16Å; L115-Y489 HydrophobicContact CG-CE2 4Å
116	M	90.5	Very high	87.9	Confident	90 Å²	90	42.4 Å²	42.4	44%	0.443	22%	0.219	S	C	.	.	H	α-helix	trans	-62.8	-45.9	168.9	-174.6	-178.3	72.9	0	0	111.8	R112 K113 M114 I118 N119 V120	R112-M116 VanDerWaalsContact O-CB 3.22Å; R112-M116 WeakPolarHBondContact O-CB 3.36Å; R112-M116 PolarHBondContact O-N 3.44Å; K113-M116 HydrophobicContact CG-CE 4.38Å; M114-M116 VanDerWaalsContact C-N 3.32Å; M114-M116 PolarHBondContact O-N 2.85Å; M116-I118 PolarHBondContact O-N 3.06Å; M116-N119 PolarHBondContact O-N 3.26Å; M116-V120 HydrophobicContact CG-CG2 3.7Å; M116-V120 VanDerWaalsContact O-CB 3.24Å; M116-V120 WeakPolarHBondContact O-CB 3.29Å; M116-V120 VanDerWaalsContact O-CG2 3.27Å; M116-V120 WeakPolarHBondContact O-CG2 3.47Å; M116-V120 PolarHBondContact O-N 3.46Å
117	G	89.9	Confident	88.2	Confident	5 Å²	5	43.8 Å²	43.8	5%	0.052	22%	0.216	C	C	.	.	H	α-helix	trans	-62.6	-38.4	179	0	0	0	0	0	113.4	K113 M114 T121	K113-G117 PolarHBondContact O-N 2.94Å; M114-G117 PolarHBondContact O-N 3.41Å; M114-G117 VanDerWaalsContact O-N 3.1Å; G117-T121 WeakPolarHBondContact O-CB 3.26Å; G117-T121 PolarHBondContact O-OG1 3.13Å
118	I	92.4	Very high	88.6	Confident	6 Å²	6	45.8 Å²	45.8	3%	0.031	22%	0.223	C	C	.	.	H	α-helix	trans	-67.7	-41.7	175.1	-69.2	164.9	0	0	0	111.3	L85 M114 M116 P122 A168 I171	L85-I118 HydrophobicContact CD1-CD1 4.24Å; M114-I118 HydrophobicContact CG-CD1 4.05Å; M114-I118 WeakPolarHBondContact O-CG1 3.17Å; M114-I118 PolarHBondContact O-N 3.08Å; M116-I118 PolarHBondContact O-N 3.06Å; I118-P122 WeakPolarHBondContact O-CD 3.16Å; I118-P122 WeakPolarHBondContact O-CG 3.32Å; I118-A168 HydrophobicContact CD1-CB 4.41Å; I118-A168 HydrophobicContact CG1-CB 4.03Å; I118-I171 HydrophobicContact CG1-CG2 4.38Å
119	N	91.6	Very high	89.1	Confident	18 Å²	18	39.9 Å²	39.9	10%	0.096	20%	0.196	C	C	.	.	H	α-helix	trans	-92.2	-27.2	-171	-68.3	-36.2	0	0	0	115.1	L115 M116 I485 Y489	L115-N119 WeakPolarHBondContact O-CB 3.38Å; L115-N119 PolarHBondContact O-N 3.27Å; L115-N119 VanDerWaalsContact O-N 3.1Å; L115-N119 PolarHBondContact O-ND2 2.89Å; M116-N119 PolarHBondContact O-N 3.26Å; N119-I485 WeakPolarHBondContact OD1-CG2 3.44Å; N119-Y489 HydrophobicContact CB-CD1 4.41Å; N119-Y489 HydrophobicContact CB-CG 4.29Å
120	V	92.8	Very high	89.2	Confident	56 Å²	56	37.6 Å²	37.6	34%	0.339	18%	0.184	S	C	.	.	H	α-helix	trans	-86.3	-44.6	-177.5	175.6	0	0	0	0	111.9	M116 P122 I123 F486	M116-V120 HydrophobicContact CG-CG2 3.7Å; M116-V120 VanDerWaalsContact O-CB 3.24Å; M116-V120 WeakPolarHBondContact O-CB 3.29Å; M116-V120 VanDerWaalsContact O-CG2 3.27Å; M116-V120 WeakPolarHBondContact O-CG2 3.47Å; M116-V120 PolarHBondContact O-N 3.46Å; V120-P122 VanDerWaalsContact C-N 3.34Å; V120-I123 HydrophobicContact CG1-CD1 4.31Å; V120-I123 VanDerWaalsContact O-CB 3.3Å; V120-I123 WeakPolarHBondContact O-CB 2.96Å; V120-I123 WeakPolarHBondContact O-CD1 3.49Å; V120-I123 WeakPolarHBondContact O-CG1 3.41Å; V120-I123 PolarHBondContact O-N 3.41Å; V120-F486 HydrophobicContact CG2-CD2 4.2Å; V120-F486 HydrophobicContact CG2-CE2 3.78Å
121	T	92.3	Very high	89.3	Confident	25 Å²	25	39.1 Å²	39.1	15%	0.153	19%	0.194	C	C	.	.	G	3₁₀ helix	trans	-54.4	-39.6	-177.5	-46.9	0	0	0	0	114.2	G117 I123 I124 V169 V173	G117-T121 WeakPolarHBondContact O-CB 3.26Å; G117-T121 PolarHBondContact O-OG1 3.13Å; T121-I123 PolarHBondContact O-N 2.87Å; T121-I123 VanDerWaalsContact O-N 3.07Å; T121-I124 PolarHBondContact O-N 3.41Å; T121-I124 VanDerWaalsContact O-N 3.16Å; T121-V169 HydrophobicContact CG2-CG1 4.29Å; T121-V173 HydrophobicContact CG2-CB 4.39Å; T121-V173 HydrophobicContact CG2-CG2 3.51Å
122	P	92.4	Very high	89.4	Confident	6 Å²	6	40.8 Å²	40.8	4%	0.039	20%	0.202	C	C	.	.	G	3₁₀ helix	trans	-57.8	-20.3	176.3	-28.6	36.7	0	0	0	115.9	I118 V120 I124 G125 G172 I175 V176 A482	I118-P122 WeakPolarHBondContact O-CD 3.16Å; I118-P122 WeakPolarHBondContact O-CG 3.32Å; V120-P122 VanDerWaalsContact C-N 3.34Å; P122-I124 VanDerWaalsContact C-N 3.28Å; P122-I124 PolarHBondContact O-N 3.17Å; P122-G125 VanDerWaalsContact O-CA 3.28Å; P122-G125 WeakPolarHBondContact O-CA 3.43Å; P122-G125 PolarHBondContact O-N 3.03Å; P122-G172 WeakPolarHBondContact CD-O 3.23Å; P122-G172 WeakPolarHBondContact CG-O 3.5Å; P122-I175 HydrophobicContact CB-CG2 4.26Å; P122-I175 HydrophobicContact CG-CG2 3.64Å; P122-V176 HydrophobicContact CB-CG2 3.98Å; P122-A482 HydrophobicContact CB-CB 3.63Å
123	I	90.3	Very high	89.3	Confident	59 Å²	59	33.6 Å²	33.6	30%	0.303	18%	0.175	S	C	.	.	G	3₁₀ helix	trans	-63.2	-38.5	178.4	-57.8	168	0	0	0	110.4	V120 T121 G125 W479 F486	V120-I123 HydrophobicContact CG1-CD1 4.31Å; V120-I123 VanDerWaalsContact O-CB 3.3Å; V120-I123 WeakPolarHBondContact O-CB 2.96Å; V120-I123 WeakPolarHBondContact O-CD1 3.49Å; V120-I123 WeakPolarHBondContact O-CG1 3.41Å; V120-I123 PolarHBondContact O-N 3.41Å; T121-I123 PolarHBondContact O-N 2.87Å; T121-I123 VanDerWaalsContact O-N 3.07Å; I123-G125 PolarHBondContact O-N 3.33Å; I123-W479 PolarHBondContact O-NE1 3.41Å; I123-F486 HydrophobicContact CD1-CB 4.46Å; I123-F486 HydrophobicContact CD1-CD1 3.51Å; I123-F486 HydrophobicContact CD1-CD2 3.9Å; I123-F486 HydrophobicContact CD1-CE1 3.53Å; I123-F486 HydrophobicContact CD1-CE2 3.95Å; I123-F486 HydrophobicContact CD1-CG 3.68Å; I123-F486 HydrophobicContact CD1-CZ 3.75Å; I123-F486 HydrophobicContact CG1-CD1 4.18Å; I123-F486 HydrophobicContact CG1-CG 4.22Å
124	I	88.1	Confident	89.1	Confident	100 Å²	100	31.8 Å²	31.8	51%	0.513	17%	0.167	S	C	.	.	G	3₁₀ helix	trans	-77.1	-7.3	175.7	-50.1	179.8	0	0	0	110.5	T121 P122 L126 L127 Y128	T121-I124 PolarHBondContact O-N 3.41Å; T121-I124 VanDerWaalsContact O-N 3.16Å; P122-I124 VanDerWaalsContact C-N 3.28Å; P122-I124 PolarHBondContact O-N 3.17Å; I124-L126 VanDerWaalsContact C-N 3.31Å; I124-L126 PolarHBondContact O-N 2.89Å; I124-L126 VanDerWaalsContact O-N 3.13Å; I124-L127 HydrophobicContact CG2-CB 4.44Å; I124-L127 HydrophobicContact CG2-CD1 3.95Å; I124-L127 HydrophobicContact CG2-CG 4.27Å; I124-L127 WeakPolarHBondContact O-CB 2.99Å; I124-L127 PolarHBondContact O-N 3.48Å; I124-Y128 HydrophobicContact CB-CE1 4.49Å; I124-Y128 HydrophobicContact CG2-CD1 4.46Å; I124-Y128 WeakPolarHBondContact O-CD1 3.27Å; I124-Y128 WeakPolarHBondContact O-CE1 3.45Å
125	G	84.8	Confident	88.8	Confident	0 Å²	0	36.5 Å²	36.5	0%	0	19%	0.188	C	C	.	.	H	α-helix	trans	-44.4	-45.7	-178.9	0	0	0	0	0	115.5	P122 I123 L127 Y128 T129	P122-G125 VanDerWaalsContact O-CA 3.28Å; P122-G125 WeakPolarHBondContact O-CA 3.43Å; P122-G125 PolarHBondContact O-N 3.03Å; I123-G125 PolarHBondContact O-N 3.33Å; G125-L127 PolarHBondContact O-N 3.36Å; G125-Y128 VanDerWaalsContact CA-CE1 3.44Å; G125-Y128 VanDerWaalsContact CA-CZ 3.48Å; G125-Y128 WeakPolarHBondContact CA-OH 3.5Å; G125-Y128 PolarHBondContact O-N 2.95Å; G125-T129 WeakPolarHBondContact O-CB 3.42Å; G125-T129 PolarHBondContact O-N 2.81Å; G125-T129 PolarHBondContact O-OG1 3.33Å
126	L	84.8	Confident	88.6	Confident	4 Å²	4	36.3 Å²	36.3	2%	0.021	19%	0.186	C	C	.	.	H	α-helix	trans	-61.3	-27.2	-177.4	-171.3	63	0	0	0	113.3	I124 P130 P333 F334 T475 I476 W479	I124-L126 VanDerWaalsContact C-N 3.31Å; I124-L126 PolarHBondContact O-N 2.89Å; I124-L126 VanDerWaalsContact O-N 3.13Å; L126-P130 WeakPolarHBondContact O-CD 3.46Å; L126-P333 HydrophobicContact CD1-CB 3.9Å; L126-P333 HydrophobicContact CG-CB 4.49Å; L126-F334 HydrophobicContact CD2-CD1 4.28Å; L126-F334 HydrophobicContact CD2-CE1 3.6Å; L126-F334 HydrophobicContact CD2-CZ 3.78Å; L126-F334 HydrophobicContact CG-CE1 4.5Å; L126-F334 HydrophobicContact CG-CZ 4.21Å; L126-T475 HydrophobicContact CD1-CG2 4.05Å; L126-I476 HydrophobicContact CD1-CG1 3.98Å; L126-W479 HydrophobicContact CB-CD2 3.88Å; L126-W479 HydrophobicContact CB-CG 3.88Å; L126-W479 HydrophobicContact CB-CZ2 4.28Å; L126-W479 HydrophobicContact CD2-CD2 3.94Å; L126-W479 HydrophobicContact CD2-CE3 3.91Å; L126-W479 HydrophobicContact CD2-CH2 3.84Å; L126-W479 HydrophobicContact CD2-CZ2 3.88Å; L126-W479 HydrophobicContact CD2-CZ3 3.86Å; L126-W479 HydrophobicContact CG-CD2 4.34Å
127	L	85.3	Confident	88.5	Confident	73 Å²	73	32.2 Å²	32.2	38%	0.382	17%	0.168	S	C	.	.	H	α-helix	trans	-74.4	-40.5	-175.6	-57	-165.2	0	0	0	112.5	I124 G125 F330 F334	I124-L127 HydrophobicContact CG2-CB 4.44Å; I124-L127 HydrophobicContact CG2-CD1 3.95Å; I124-L127 HydrophobicContact CG2-CG 4.27Å; I124-L127 WeakPolarHBondContact O-CB 2.99Å; I124-L127 PolarHBondContact O-N 3.48Å; G125-L127 PolarHBondContact O-N 3.36Å; L127-F330 HydrophobicContact CB-CE2 3.95Å; L127-F330 HydrophobicContact CD2-CE2 3.93Å; L127-F330 HydrophobicContact CD2-CZ 3.88Å; L127-F330 HydrophobicContact CG-CE2 4.4Å; L127-F334 HydrophobicContact CD2-CE2 4.2Å; L127-F334 HydrophobicContact CD2-CZ 3.79Å
128	Y	88.9	Confident	88.4	Confident	46 Å²	46	32.1 Å²	32.1	18%	0.18	17%	0.166	C	C	.	.	H	α-helix	trans	-104.2	-28.6	-175.4	63.5	-101.2	0	0	0	113.6	I124 G125 V131 L132 V173 P177	I124-Y128 HydrophobicContact CB-CE1 4.49Å; I124-Y128 HydrophobicContact CG2-CD1 4.46Å; I124-Y128 WeakPolarHBondContact O-CD1 3.27Å; I124-Y128 WeakPolarHBondContact O-CE1 3.45Å; G125-Y128 VanDerWaalsContact CA-CE1 3.44Å; G125-Y128 VanDerWaalsContact CA-CZ 3.48Å; G125-Y128 WeakPolarHBondContact CA-OH 3.5Å; G125-Y128 PolarHBondContact O-N 2.95Å; Y128-V131 PolarHBondContact O-N 3.4Å; Y128-V131 VanDerWaalsContact O-N 3.12Å; Y128-L132 HydrophobicContact CD2-CD1 3.62Å; Y128-L132 HydrophobicContact CD2-CG 4.25Å; Y128-L132 HydrophobicContact CE2-CD1 4.23Å; Y128-L132 WeakPolarHBondContact O-CG 3.4Å; Y128-L132 PolarHBondContact O-N 3.21Å; Y128-V173 HydrophobicContact CD2-CG1 4.36Å; Y128-V173 HydrophobicContact CE2-CG1 3.69Å; Y128-V173 VanDerWaalsContact CE2-O 3.3Å; Y128-V173 WeakPolarHBondContact CE2-O 3.45Å; Y128-V173 VanDerWaalsContact OH-CA 3.25Å; Y128-V173 WeakPolarHBondContact OH-CA 3.3Å; Y128-V173 PolarHBondContact OH-O 3.24Å; Y128-P177 HydrophobicContact CE2-CG 3.86Å
129	T	90	Very high	88.3	Confident	0 Å²	0	33.8 Å²	33.8	0%	0	17%	0.173	C	C	.	.	H	α-helix	trans	-55.9	-47.5	-173.4	-61.1	0	0	0	0	113.7	G125 V131 L132 I133 V176 P177 A180 T475	G125-T129 WeakPolarHBondContact O-CB 3.42Å; G125-T129 PolarHBondContact O-N 2.81Å; G125-T129 PolarHBondContact O-OG1 3.33Å; T129-V131 VanDerWaalsContact C-N 3.29Å; T129-V131 PolarHBondContact O-N 3.28Å; T129-L132 PolarHBondContact O-N 3.35Å; T129-I133 HydrophobicContact CG2-CD1 3.61Å; T129-I133 HydrophobicContact CG2-CG1 4.31Å; T129-I133 WeakPolarHBondContact O-CG1 3.18Å; T129-I133 PolarHBondContact O-N 2.84Å; T129-V176 HydrophobicContact CG2-CG1 4.4Å; T129-P177 HydrophobicContact CG2-CB 3.96Å; T129-P177 HydrophobicContact CG2-CG 3.83Å; T129-P177 WeakPolarHBondContact OG1-CD 3.5Å; T129-P177 WeakPolarHBondContact OG1-CG 3.33Å; T129-A180 HydrophobicContact CG2-CB 4.31Å; T129-T475 HydrophobicContact CG2-CG2 3.6Å
130	P	87.4	Confident	88.3	Confident	4 Å²	4	39.3 Å²	39.3	3%	0.026	19%	0.192	C	C	.	.	H	α-helix	trans	-63.3	-37.3	179.2	-18	30.4	0	0	0	112.4	L126 R134 I329 P333 F472 T475	L126-P130 WeakPolarHBondContact O-CD 3.46Å; P130-R134 WeakPolarHBondContact O-CB 3.44Å; P130-R134 VanDerWaalsContact O-CG 3.24Å; P130-R134 WeakPolarHBondContact O-CG 3.43Å; P130-R134 PolarHBondContact O-N 3.31Å; P130-R134 VanDerWaalsContact O-N 3.09Å; P130-I329 HydrophobicContact CB-CG2 4.29Å; P130-P333 HydrophobicContact CB-CG 4.18Å; P130-P333 HydrophobicContact CG-CG 3.57Å; P130-F472 HydrophobicContact CB-CD1 3.95Å; P130-F472 HydrophobicContact CB-CE1 3.86Å; P130-T475 HydrophobicContact CG-CG2 4.14Å
131	V	87.1	Confident	88.3	Confident	43 Å²	43	36.8 Å²	36.8	26%	0.261	18%	0.177	S	C	.	.	H	α-helix	trans	-68.1	-45.1	178.9	178.9	0	0	0	0	110.5	Y128 T129 R134 F135 W326 I329	Y128-V131 PolarHBondContact O-N 3.4Å; Y128-V131 VanDerWaalsContact O-N 3.12Å; T129-V131 VanDerWaalsContact C-N 3.29Å; T129-V131 PolarHBondContact O-N 3.28Å; V131-R134 PolarHBondContact O-N 3.11Å; V131-F135 VanDerWaalsContact O-CB 3.26Å; V131-F135 WeakPolarHBondContact O-CB 3.27Å; V131-F135 PolarHBondContact O-N 3.46Å; V131-W326 HydrophobicContact CG1-CE3 3.96Å; V131-W326 HydrophobicContact CG1-CZ3 3.94Å; V131-I329 HydrophobicContact CG2-CG2 4.14Å
132	L	88.3	Confident	88.4	Confident	53 Å²	53	35.7 Å²	35.7	28%	0.277	17%	0.17	S	C	.	.	H	α-helix	trans	-63.3	-45.3	177.3	-68.5	-173.9	0	0	0	112.2	Y128 T129 R134 F135 L136 M141	Y128-L132 HydrophobicContact CD2-CD1 3.62Å; Y128-L132 HydrophobicContact CD2-CG 4.25Å; Y128-L132 HydrophobicContact CE2-CD1 4.23Å; Y128-L132 WeakPolarHBondContact O-CG 3.4Å; Y128-L132 PolarHBondContact O-N 3.21Å; T129-L132 PolarHBondContact O-N 3.35Å; L132-R134 VanDerWaalsContact C-N 3.3Å; L132-R134 PolarHBondContact O-N 2.92Å; L132-F135 PolarHBondContact O-N 2.7Å; L132-L136 WeakPolarHBondContact O-CB 3.49Å; L132-L136 PolarHBondContact O-N 3.23Å; L132-M141 HydrophobicContact CB-SD 3.96Å; L132-M141 HydrophobicContact CD1-SD 4.48Å
133	I	88	Confident	88.5	Confident	3 Å²	3	37.8 Å²	37.8	2%	0.015	18%	0.179	C	C	.	.	H	α-helix	trans	-62.3	-38.6	178.5	-68.1	170.6	0	0	0	110.8	T129 G137 I138 M141 A180 D471	T129-I133 HydrophobicContact CG2-CD1 3.61Å; T129-I133 HydrophobicContact CG2-CG1 4.31Å; T129-I133 WeakPolarHBondContact O-CG1 3.18Å; T129-I133 PolarHBondContact O-N 2.84Å; I133-G137 CarbonylContact O-C 3.58Å; I133-G137 WeakPolarHBondContact O-CA 3.48Å; I133-G137 PolarHBondContact O-N 2.77Å; I133-I138 HydrophobicContact CG2-CG1 4.14Å; I133-M141 HydrophobicContact CG1-CG 4.02Å; I133-A180 HydrophobicContact CD1-CB 3.87Å; I133-D471 HydrophobicContact CG2-CB 4.28Å
134	R	85.2	Confident	88.8	Confident	18 Å²	18	38.7 Å²	38.7	7%	0.068	18%	0.184	C	C	.	.	H	α-helix	trans	-77.4	-29.9	178.4	-69.7	-71.8	162.3	120.6	-2.1	114.4	P130 V131 L132 I329 E468 D471	P130-R134 WeakPolarHBondContact O-CB 3.44Å; P130-R134 VanDerWaalsContact O-CG 3.24Å; P130-R134 WeakPolarHBondContact O-CG 3.43Å; P130-R134 PolarHBondContact O-N 3.31Å; P130-R134 VanDerWaalsContact O-N 3.09Å; V131-R134 PolarHBondContact O-N 3.11Å; L132-R134 VanDerWaalsContact C-N 3.3Å; L132-R134 PolarHBondContact O-N 2.92Å; R134-I329 HydrophobicContact CB-CD1 4.25Å; R134-I329 HydrophobicContact CG-CD1 4.42Å; R134-I329 HydrophobicContact CG-CG2 4.45Å; R134-E468 PolarHBondContact NH2-O 3.21Å; R134-D471 IonicContact CZ-OD2 3.6Å; R134-D471 IonicContact NE-OD2 3.96Å; R134-D471 PolarHBondContact NE-OD2 3.24Å; R134-D471 IonicContact NH2-OD2 3.21Å; R134-D471 PolarHBondContact NH2-OD2 3.09Å
135	F	85.4	Confident	89.1	Confident	104 Å²	104	33.9 Å²	33.9	46%	0.456	16%	0.159	S	C	.	.	H	α-helix	trans	-78.5	-43.1	178.1	177.5	-103.6	0	0	0	112.7	V131 L132 W326	V131-F135 VanDerWaalsContact O-CB 3.26Å; V131-F135 WeakPolarHBondContact O-CB 3.27Å; V131-F135 PolarHBondContact O-N 3.46Å; L132-F135 PolarHBondContact O-N 2.7Å; F135-W326 HydrophobicContact CB-CH2 3.84Å; F135-W326 HydrophobicContact CB-CZ3 4.1Å; F135-W326 AromaticContact CD2-CH2 3.79Å; F135-W326 HydrophobicContact CD2-CH2 3.79Å; F135-W326 HydrophobicContact CD2-CZ2 4.25Å; F135-W326 HydrophobicContact CG-CH2 4.3Å
136	L	86.1	Confident	89.6	Confident	49 Å²	49	34 Å²	34	26%	0.257	16%	0.16	S	C	.	.	H	α-helix	trans	-88.6	-30.7	-178.2	-61.7	174.8	0	0	0	112.9	L132 W140 M141 L144	L132-L136 WeakPolarHBondContact O-CB 3.49Å; L132-L136 PolarHBondContact O-N 3.23Å; L136-W140 HydrophobicContact CB-CB 4.18Å; L136-W140 WeakPolarHBondContact O-CB 3.32Å; L136-M141 HydrophobicContact CD1-SD 4.08Å; L136-L144 HydrophobicContact CD1-CD2 3.5Å; L136-L144 VanDerWaalsContact CD1-CD2 3.5Å
137	G	87	Confident	90.2	Very high	5 Å²	5	35 Å²	35	5%	0.052	17%	0.171	C	C	.	.			trans	85	153.3	-166.3	0	0	0	0	0	112.4	I133 K139 W140 M141 E318	I133-G137 CarbonylContact O-C 3.58Å; I133-G137 WeakPolarHBondContact O-CA 3.48Å; I133-G137 PolarHBondContact O-N 2.77Å; G137-K139 PolarHBondContact O-N 3.29Å; G137-W140 PolarHBondContact O-N 3.25Å; G137-M141 PolarHBondContact O-N 3.14Å; G137-E318 WeakPolarHBondContact CA-OE1 3.36Å
138	I	88.3	Confident	90.7	Very high	3 Å²	3	33.2 Å²	33.2	2%	0.015	16%	0.161	C	C	.	.	H	α-helix	trans	-55.6	-49.4	-172.6	-63.4	-179.3	0	0	0	112.2	I133 W140 M141 M142 S181 Y185 A312 Y313 D471	I133-I138 HydrophobicContact CG2-CG1 4.14Å; I138-W140 PolarHBondContact O-N 3.02Å; I138-M141 PolarHBondContact O-N 2.7Å; I138-M142 HydrophobicContact CG2-SD 4.02Å; I138-M142 WeakPolarHBondContact O-CG 3.47Å; I138-M142 PolarHBondContact O-N 2.59Å; I138-M142 VanDerWaalsContact O-N 3.11Å; I138-S181 VanDerWaalsContact CG2-O 3.27Å; I138-S181 WeakPolarHBondContact CG2-O 3.45Å; I138-Y185 HydrophobicContact CG2-CD2 3.83Å; I138-Y185 HydrophobicContact CG2-CG 4.31Å; I138-A312 HydrophobicContact CB-CB 4.4Å; I138-A312 HydrophobicContact CD1-CB 4.38Å; I138-Y313 HydrophobicContact CD1-CD2 4.13Å; I138-Y313 HydrophobicContact CD1-CE2 3.38Å; I138-Y313 HydrophobicContact CG1-CD2 4.47Å; I138-Y313 HydrophobicContact CG1-CE2 3.94Å; I138-D471 WeakPolarHBondContact CD1-OD1 3.4Å
139	K	90.5	Very high	91	Very high	41 Å²	41	31.3 Å²	31.3	18%	0.178	15%	0.154	C	C	.	.	H	α-helix	trans	-59.7	-47.3	-178.3	173.6	-179.4	170.4	169.2	0	111.5	G137 M142 F143 F305 L306 C309	G137-K139 PolarHBondContact O-N 3.29Å; K139-M142 PolarHBondContact O-N 3.38Å; K139-F143 PolarHBondContact O-N 3.02Å; K139-F305 WeakPolarHBondContact CE-O 3.27Å; K139-L306 WeakPolarHBondContact CE-O 3.45Å; K139-L306 PolarHBondContact NZ-O 3.3Å; K139-C309 WeakPolarHBondContact CD-O 3.42Å; K139-C309 WeakPolarHBondContact CE-O 3.22Å; K139-C309 PolarHBondContact NZ-O 3.35Å
140	W	91.6	Very high	91.3	Very high	133 Å²	133	31.5 Å²	31.5	50%	0.504	16%	0.156	S	C	.	.	H	α-helix	trans	-71.5	-32.4	-176.1	-63.6	110.5	0	0	0	112	L136 G137 I138 F143 L144 L306	L136-W140 HydrophobicContact CB-CB 4.18Å; L136-W140 WeakPolarHBondContact O-CB 3.32Å; G137-W140 PolarHBondContact O-N 3.25Å; I138-W140 PolarHBondContact O-N 3.02Å; W140-F143 HydrophobicContact CE3-CD1 4.29Å; W140-F143 PolarHBondContact O-N 2.97Å; W140-L144 VanDerWaalsContact O-CB 3.27Å; W140-L144 WeakPolarHBondContact O-CB 3.22Å; W140-L144 PolarHBondContact O-N 3.5Å; W140-L306 HydrophobicContact CH2-CD1 4.31Å; W140-L306 HydrophobicContact CZ3-CD1 3.83Å
141	M	93.1	Very high	91.6	Very high	3 Å²	3	35.7 Å²	35.7	2%	0.015	18%	0.177	C	C	.	.	H	α-helix	trans	-62.3	-43.3	170.3	-172.8	69.1	-105	0	0	111.8	L132 I133 L136 G137 I138 L144 A145 P177	L132-M141 HydrophobicContact CB-SD 3.96Å; L132-M141 HydrophobicContact CD1-SD 4.48Å; I133-M141 HydrophobicContact CG1-CG 4.02Å; L136-M141 HydrophobicContact CD1-SD 4.08Å; G137-M141 PolarHBondContact O-N 3.14Å; I138-M141 PolarHBondContact O-N 2.7Å; M141-L144 HydrophobicContact CE-CB 4.42Å; M141-L144 HydrophobicContact CE-CD2 4.21Å; M141-L144 HydrophobicContact CE-CG 4.47Å; M141-L144 PolarHBondContact O-N 3.31Å; M141-A145 HydrophobicContact CE-CB 4.12Å; M141-A145 VanDerWaalsContact O-CB 3.26Å; M141-A145 WeakPolarHBondContact O-CB 3.29Å; M141-A145 PolarHBondContact O-N 2.92Å; M141-P177 HydrophobicContact CE-CB 3.79Å; M141-P177 HydrophobicContact CG-CB 3.89Å; M141-P177 HydrophobicContact SD-CB 3.62Å
142	M	94	Very high	92	Very high	2 Å²	2	33.7 Å²	33.7	1%	0.01	17%	0.165	C	C	.	.	H	α-helix	trans	-61.7	-45.1	175.6	-68	166.8	55	0	0	111.8	I138 K139 S146 S181 L182 Y185 F305	I138-M142 HydrophobicContact CG2-SD 4.02Å; I138-M142 WeakPolarHBondContact O-CG 3.47Å; I138-M142 PolarHBondContact O-N 2.59Å; I138-M142 VanDerWaalsContact O-N 3.11Å; K139-M142 PolarHBondContact O-N 3.38Å; M142-S146 WeakPolarHBondContact O-CB 3.37Å; M142-S146 PolarHBondContact O-N 3.38Å; M142-S181 VanDerWaalsContact CG-OG 3.3Å; M142-S181 WeakPolarHBondContact CG-OG 3.45Å; M142-L182 HydrophobicContact CE-CD1 3.64Å; M142-Y185 HydrophobicContact CE-CD1 4.25Å; M142-Y185 HydrophobicContact CE-CG 4.19Å; M142-Y185 HydrophobicContact SD-CD1 4.42Å; M142-Y185 HydrophobicContact SD-CD2 3.9Å; M142-Y185 HydrophobicContact SD-CG 3.77Å; M142-F305 HydrophobicContact CB-CD1 4.33Å; M142-F305 HydrophobicContact CE-CD1 3.65Å; M142-F305 HydrophobicContact CE-CE1 3.41Å; M142-F305 VanDerWaalsContact CE-CE1 3.41Å; M142-F305 HydrophobicContact CE-CZ 4.46Å
143	F	95.2	Very high	92.3	Very high	51 Å²	51	31.4 Å²	31.4	22%	0.224	15%	0.153	C	C	.	.	H	α-helix	trans	-60.9	-52.7	175	171.4	-100.5	0	0	0	112	K139 W140 A145 S146 G147 M302 F305 L306	K139-F143 PolarHBondContact O-N 3.02Å; W140-F143 HydrophobicContact CE3-CD1 4.29Å; W140-F143 PolarHBondContact O-N 2.97Å; F143-A145 VanDerWaalsContact C-N 3.34Å; F143-A145 PolarHBondContact O-N 3.23Å; F143-S146 PolarHBondContact O-N 2.94Å; F143-S146 VanDerWaalsContact O-N 3.13Å; F143-S146 PolarHBondContact O-OG 3.12Å; F143-G147 PolarHBondContact O-N 3.35Å; F143-M302 HydrophobicContact CD2-CG 3.83Å; F143-M302 HydrophobicContact CE2-CE 4.5Å; F143-M302 HydrophobicContact CE2-CG 3.47Å; F143-M302 VanDerWaalsContact CE2-CG 3.47Å; F143-M302 HydrophobicContact CE2-SD 4.12Å; F143-M302 HydrophobicContact CZ-CG 4.26Å; F143-M302 HydrophobicContact CZ-SD 4.37Å; F143-F305 HydrophobicContact CB-CB 4.48Å; F143-L306 HydrophobicContact CD2-CB 3.81Å; F143-L306 HydrophobicContact CD2-CD1 4.05Å; F143-L306 HydrophobicContact CD2-CG 4.41Å; F143-L306 HydrophobicContact CE2-CB 3.78Å; F143-L306 HydrophobicContact CE2-CD1 3.89Å; F143-L306 HydrophobicContact CE2-CD2 4.02Å; F143-L306 HydrophobicContact CE2-CG 4.11Å; F143-L306 HydrophobicContact CG-CD1 4.47Å; F143-L306 HydrophobicContact CZ-CD1 4.21Å; F143-L306 HydrophobicContact CZ-CD2 4.41Å
144	L	95.2	Very high	92.5	Very high	77 Å²	77	33.9 Å²	33.9	40%	0.403	17%	0.171	S	C	.	.	H	α-helix	trans	-58.4	-45	179.9	177.9	63.6	0	0	0	111.6	L136 W140 M141 G147 I148	L136-L144 HydrophobicContact CD1-CD2 3.5Å; L136-L144 VanDerWaalsContact CD1-CD2 3.5Å; W140-L144 VanDerWaalsContact O-CB 3.27Å; W140-L144 WeakPolarHBondContact O-CB 3.22Å; W140-L144 PolarHBondContact O-N 3.5Å; M141-L144 HydrophobicContact CE-CB 4.42Å; M141-L144 HydrophobicContact CE-CD2 4.21Å; M141-L144 HydrophobicContact CE-CG 4.47Å; M141-L144 PolarHBondContact O-N 3.31Å; L144-G147 PolarHBondContact O-N 2.74Å; L144-I148 HydrophobicContact CG-CD1 4.31Å; L144-I148 WeakPolarHBondContact O-CG1 3.45Å; L144-I148 PolarHBondContact O-N 2.92Å
145	A	95.3	Very high	92.9	Very high	0 Å²	0	34.2 Å²	34.2	0%	0	18%	0.175	C	C	.	.	H	α-helix	trans	-62.6	-43	176.1	0	0	0	0	0	112.1	M141 F143 G147 I148 Y149 A174 F178	M141-A145 HydrophobicContact CE-CB 4.12Å; M141-A145 VanDerWaalsContact O-CB 3.26Å; M141-A145 WeakPolarHBondContact O-CB 3.29Å; M141-A145 PolarHBondContact O-N 2.92Å; F143-A145 VanDerWaalsContact C-N 3.34Å; F143-A145 PolarHBondContact O-N 3.23Å; A145-G147 VanDerWaalsContact C-N 3.26Å; A145-G147 PolarHBondContact O-N 3.06Å; A145-I148 WeakPolarHBondContact O-CB 3.4Å; A145-I148 PolarHBondContact O-N 3.09Å; A145-I148 VanDerWaalsContact O-N 3.08Å; A145-Y149 VanDerWaalsContact O-CD2 3.27Å; A145-Y149 WeakPolarHBondContact O-CD2 3.3Å; A145-Y149 PolarHBondContact O-N 3.4Å; A145-A174 HydrophobicContact CB-CB 4.21Å; A145-F178 HydrophobicContact CB-CB 3.76Å; A145-F178 HydrophobicContact CB-CD2 3.72Å; A145-F178 HydrophobicContact CB-CG 4.13Å
146	S	95.7	Very high	93.1	Very high	2 Å²	2	29.4 Å²	29.4	1%	0.014	15%	0.154	C	C	.	.	H	α-helix	trans	-61	-35.5	174.6	74.8	0	0	0	0	112.5	M142 F143 Y149 A150	M142-S146 WeakPolarHBondContact O-CB 3.37Å; M142-S146 PolarHBondContact O-N 3.38Å; F143-S146 PolarHBondContact O-N 2.94Å; F143-S146 VanDerWaalsContact O-N 3.13Å; F143-S146 PolarHBondContact O-OG 3.12Å; S146-Y149 PolarHBondContact O-N 2.9Å; S146-A150 PolarHBondContact O-N 3.36Å
147	G	96	Very high	93.3	Very high	24 Å²	24	31.3 Å²	31.3	25%	0.247	16%	0.158	C	C	.	.	H	α-helix	trans	-65.5	-36.4	171.8	0	0	0	0	0	113.3	F143 L144 A145 A150 L151	F143-G147 PolarHBondContact O-N 3.35Å; L144-G147 PolarHBondContact O-N 2.74Å; A145-G147 VanDerWaalsContact C-N 3.26Å; A145-G147 PolarHBondContact O-N 3.06Å; G147-A150 PolarHBondContact O-N 3.35Å; G147-L151 WeakPolarHBondContact O-CB 3.46Å; G147-L151 PolarHBondContact O-N 2.88Å
148	I	96.3	Very high	93.3	Very high	36 Å²	36	38.1 Å²	38.1	19%	0.185	18%	0.183	C	C	.	.	H	α-helix	trans	-68.2	-40.4	173.9	-68.1	166.3	0	0	0	111.2	L144 A145 L151 F152 A170 I171 A174	L144-I148 HydrophobicContact CG-CD1 4.31Å; L144-I148 WeakPolarHBondContact O-CG1 3.45Å; L144-I148 PolarHBondContact O-N 2.92Å; A145-I148 WeakPolarHBondContact O-CB 3.4Å; A145-I148 PolarHBondContact O-N 3.09Å; A145-I148 VanDerWaalsContact O-N 3.08Å; I148-L151 PolarHBondContact O-N 2.93Å; I148-F152 PolarHBondContact O-N 3.37Å; I148-A170 HydrophobicContact CG2-CB 3.75Å; I148-A170 WeakPolarHBondContact CG2-O 3.4Å; I148-I171 HydrophobicContact CG2-CG1 4.35Å; I148-A174 HydrophobicContact CB-CB 4.15Å; I148-A174 HydrophobicContact CD1-CB 3.86Å; I148-A174 HydrophobicContact CG2-CB 3.92Å
149	Y	95.4	Very high	93.2	Very high	7 Å²	7	38.4 Å²	38.4	3%	0.027	18%	0.184	C	C	.	.	H	α-helix	trans	-60.9	-44.7	171.3	-82.2	-75.8	0	0	0	111.6	V77 Y81 A145 S146 L151 F152 V153 I171 I175 F178	V77-Y149 HydrophobicContact CG1-CD1 4.18Å; V77-Y149 HydrophobicContact CG1-CD2 3.6Å; V77-Y149 HydrophobicContact CG1-CE2 4.22Å; V77-Y149 HydrophobicContact CG1-CG 3.59Å; Y81-Y149 AromaticContact CD1-CE1 3.99Å; Y81-Y149 HydrophobicContact CD1-CE1 3.99Å; Y81-Y149 AromaticContact CD2-CD1 3.86Å; Y81-Y149 HydrophobicContact CD2-CD1 3.86Å; Y81-Y149 AromaticContact CD2-CE1 3.75Å; Y81-Y149 HydrophobicContact CD2-CE1 3.75Å; Y81-Y149 HydrophobicContact CE1-CE1 4.38Å; Y81-Y149 HydrophobicContact CE2-CE1 4.18Å; Y81-Y149 AromaticContact CG-CD1 3.89Å; Y81-Y149 HydrophobicContact CG-CD1 3.89Å; Y81-Y149 AromaticContact CG-CE1 3.65Å; Y81-Y149 HydrophobicContact CG-CE1 3.65Å; A145-Y149 VanDerWaalsContact O-CD2 3.27Å; A145-Y149 WeakPolarHBondContact O-CD2 3.3Å; A145-Y149 PolarHBondContact O-N 3.4Å; S146-Y149 PolarHBondContact O-N 2.9Å; Y149-L151 PolarHBondContact O-N 2.92Å; Y149-F152 WeakPolarHBondContact O-CB 3.21Å; Y149-F152 PolarHBondContact O-N 2.85Å; Y149-V153 WeakPolarHBondContact O-CG2 3.12Å; Y149-V153 PolarHBondContact O-N 2.9Å; Y149-V153 VanDerWaalsContact O-N 3.15Å; Y149-I171 HydrophobicContact CD1-CD1 3.89Å; Y149-I171 HydrophobicContact CD1-CG1 4.24Å; Y149-I171 HydrophobicContact CE1-CD1 4.08Å; Y149-I171 HydrophobicContact CE1-CG1 4.34Å; Y149-I171 HydrophobicContact CE1-CG2 4.07Å; Y149-I175 WeakPolarHBondContact OH-CG1 3.49Å; Y149-F178 HydrophobicContact CE2-CB 4.49Å; Y149-F178 HydrophobicContact CE2-CD1 4.19Å; Y149-F178 HydrophobicContact CE2-CG 4.23Å
150	A	95.5	Very high	93	Very high	4 Å²	4	40 Å²	40	3%	0.033	19%	0.189	C	C	.	.	H	α-helix	trans	-62.9	-39.2	174.7	0	0	0	0	0	112.4	S146 G147 F152 V153 S154 M295 A298	S146-A150 PolarHBondContact O-N 3.36Å; G147-A150 PolarHBondContact O-N 3.35Å; A150-F152 VanDerWaalsContact C-N 3.33Å; A150-F152 PolarHBondContact O-N 3.03Å; A150-V153 PolarHBondContact O-N 3.33Å; A150-S154 PolarHBondContact O-N 2.86Å; A150-M295 HydrophobicContact CB-CE 4.08Å; A150-M295 WeakPolarHBondContact O-CE 3.23Å; A150-M295 VanDerWaalsContact O-SD 3.41Å; A150-A298 HydrophobicContact CB-CB 3.93Å
151	L	95.1	Very high	92.8	Very high	91 Å²	91	39.4 Å²	39.4	48%	0.476	19%	0.187	S	C	.	.	H	α-helix	trans	-61.2	-40.9	174.8	-176.8	149.8	0	0	0	111.5	G147 I148 Y149 S154 T155	G147-L151 WeakPolarHBondContact O-CB 3.46Å; G147-L151 PolarHBondContact O-N 2.88Å; I148-L151 PolarHBondContact O-N 2.93Å; Y149-L151 PolarHBondContact O-N 2.92Å; L151-S154 WeakPolarHBondContact O-CB 3.44Å; L151-S154 PolarHBondContact O-N 3.36Å; L151-T155 HydrophobicContact CD2-CG2 4.14Å; L151-T155 WeakPolarHBondContact O-CG2 3.14Å; L151-T155 PolarHBondContact O-N 2.95Å; L151-T155 PolarHBondContact O-OG1 2.71Å
152	F	94.5	Very high	92.5	Very high	2 Å²	2	46.7 Å²	46.7	1%	0.009	22%	0.216	C	C	.	.	H	α-helix	trans	-60.1	-47.4	173.4	175.4	-101.5	0	0	0	111.9	Y81 L84 M114 I148 Y149 A150 S154 T155 N156 L164 I171	Y81-F152 HydrophobicContact CD2-CD1 4.37Å; Y81-F152 HydrophobicContact CD2-CE1 4.31Å; Y81-F152 HydrophobicContact CE2-CE1 4.33Å; L84-F152 HydrophobicContact CD2-CD1 4.3Å; L84-F152 HydrophobicContact CD2-CE1 4.13Å; M114-F152 HydrophobicContact CG-CE2 4.42Å; M114-F152 HydrophobicContact SD-CE2 3.99Å; M114-F152 HydrophobicContact SD-CZ 3.93Å; I148-F152 PolarHBondContact O-N 3.37Å; Y149-F152 WeakPolarHBondContact O-CB 3.21Å; Y149-F152 PolarHBondContact O-N 2.85Å; A150-F152 VanDerWaalsContact C-N 3.33Å; A150-F152 PolarHBondContact O-N 3.03Å; F152-S154 VanDerWaalsContact C-N 3.29Å; F152-S154 PolarHBondContact O-N 2.76Å; F152-T155 WeakPolarHBondContact CA-OG1 3.49Å; F152-T155 PolarHBondContact O-N 3.13Å; F152-T155 VanDerWaalsContact O-N 3.09Å; F152-T155 PolarHBondContact O-OG1 2.85Å; F152-N156 PolarHBondContact O-N 2.96Å; F152-N156 PolarHBondContact O-ND2 3.19Å; F152-L164 HydrophobicContact CD2-CD1 4.46Å; F152-L164 HydrophobicContact CE2-CD1 3.88Å; F152-L164 HydrophobicContact CZ-CD1 4.47Å; F152-I171 HydrophobicContact CB-CD1 3.38Å; F152-I171 HydrophobicContact CB-CG1 3.96Å; F152-I171 HydrophobicContact CD1-CD1 3.52Å; F152-I171 HydrophobicContact CD2-CD1 3.75Å; F152-I171 HydrophobicContact CE1-CD1 4.2Å; F152-I171 HydrophobicContact CE2-CD1 4.4Å; F152-I171 HydrophobicContact CG-CD1 3.26Å; F152-I171 HydrophobicContact CG-CG1 4.23Å
153	V	93.9	Very high	92.4	Very high	5 Å²	5	48.2 Å²	48.2	3%	0.03	23%	0.225	C	C	.	.	H	α-helix	trans	-55	-47.2	174.4	-179	0	0	0	0	110.7	V80 L84 Y149 A150 T155 N156 M295	V80-V153 HydrophobicContact CG1-CG2 3.6Å; L84-V153 HydrophobicContact CD2-CB 4.11Å; L84-V153 HydrophobicContact CD2-CG1 4.11Å; L84-V153 HydrophobicContact CD2-CG2 3.89Å; Y149-V153 WeakPolarHBondContact O-CG2 3.12Å; Y149-V153 PolarHBondContact O-N 2.9Å; Y149-V153 VanDerWaalsContact O-N 3.15Å; A150-V153 PolarHBondContact O-N 3.33Å; V153-T155 VanDerWaalsContact C-N 3.34Å; V153-T155 PolarHBondContact O-N 3.33Å; V153-N156 WeakPolarHBondContact O-CB 3.5Å; V153-N156 PolarHBondContact O-N 3.23Å; V153-M295 HydrophobicContact CB-SD 3.8Å; V153-M295 HydrophobicContact CG1-CB 4.1Å; V153-M295 HydrophobicContact CG1-SD 3.73Å
154	S	93.6	Very high	92.2	Very high	55 Å²	55	45.9 Å²	45.9	39%	0.385	22%	0.215	S	C	.	.	H	α-helix	trans	-58.9	-39.7	176.2	-171.6	0	0	0	0	113.2	A150 L151 F152 N156 Y157	A150-S154 PolarHBondContact O-N 2.86Å; L151-S154 WeakPolarHBondContact O-CB 3.44Å; L151-S154 PolarHBondContact O-N 3.36Å; F152-S154 VanDerWaalsContact C-N 3.29Å; F152-S154 PolarHBondContact O-N 2.76Å; S154-N156 PolarHBondContact O-N 3.28Å; S154-Y157 VanDerWaalsContact O-CD2 3.25Å; S154-Y157 WeakPolarHBondContact O-CD2 3.19Å; S154-Y157 PolarHBondContact O-N 3.34Å
155	T	93.1	Very high	92	Very high	25 Å²	25	43.2 Å²	43.2	15%	0.153	20%	0.202	C	C	.	.	H	α-helix	trans	-68.6	-15.4	176.7	55.3	0	0	0	0	114.5	L151 F152 V153 W158 S167	L151-T155 HydrophobicContact CD2-CG2 4.14Å; L151-T155 WeakPolarHBondContact O-CG2 3.14Å; L151-T155 PolarHBondContact O-N 2.95Å; L151-T155 PolarHBondContact O-OG1 2.71Å; F152-T155 WeakPolarHBondContact CA-OG1 3.49Å; F152-T155 PolarHBondContact O-N 3.13Å; F152-T155 VanDerWaalsContact O-N 3.09Å; F152-T155 PolarHBondContact O-OG1 2.85Å; V153-T155 VanDerWaalsContact C-N 3.34Å; V153-T155 PolarHBondContact O-N 3.33Å; T155-W158 CarbonylContact O-C 3.57Å; T155-W158 PolarHBondContact O-N 3.23Å; T155-S167 WeakPolarHBondContact OG1-CB 3.38Å; T155-S167 PolarHBondContact OG1-OG 2.87Å
156	N	90.4	Very high	92	Very high	3 Å²	3	46.9 Å²	46.9	2%	0.016	23%	0.226	C	C	.	.	H	α-helix	trans	-77	-18.8	175.8	-77	-99.6	0	0	0	113	L84 F152 V153 S154 W158 E159	L84-N156 HydrophobicContact CD1-CB 4.31Å; L84-N156 HydrophobicContact CD2-CB 4.11Å; F152-N156 PolarHBondContact O-N 2.96Å; F152-N156 PolarHBondContact O-ND2 3.19Å; V153-N156 WeakPolarHBondContact O-CB 3.5Å; V153-N156 PolarHBondContact O-N 3.23Å; S154-N156 PolarHBondContact O-N 3.28Å; N156-W158 PolarHBondContact O-N 3.46Å; N156-W158 VanDerWaalsContact O-N 3.14Å; N156-E159 WeakPolarHBondContact O-CG 3.18Å
157	Y	90.4	Very high	91.9	Very high	89 Å²	89	46.9 Å²	46.9	35%	0.349	23%	0.226	S	C	.	.	T	Hydrogen-bonded Turn	trans	-59.7	-26.9	170.4	-69.3	-60	0	0	0	113.2	S154 E291 S292 M295	S154-Y157 VanDerWaalsContact O-CD2 3.25Å; S154-Y157 WeakPolarHBondContact O-CD2 3.19Å; S154-Y157 PolarHBondContact O-N 3.34Å; Y157-E291 HydrophobicContact CD1-CB 4.1Å; Y157-E291 HydrophobicContact CE1-CB 3.75Å; Y157-S292 WeakPolarHBondContact OH-CA 3.36Å; Y157-S292 PolarHBondContact OH-OG 3.47Å; Y157-M295 HydrophobicContact CE2-CG 4.43Å
158	W	86.8	Confident	91.8	Very high	148 Å²	148	45.8 Å²	45.8	56%	0.561	21%	0.214	S	C	*	.	T	Hydrogen-bonded Turn	trans	-135.6	71.9	177.9	-161.8	-103.8	0	0	0	110	T155 N156 R160 T163	T155-W158 CarbonylContact O-C 3.57Å; T155-W158 PolarHBondContact O-N 3.23Å; N156-W158 PolarHBondContact O-N 3.46Å; N156-W158 VanDerWaalsContact O-N 3.14Å; W158-R160 HydrophobicContact CG-CG 4.27Å; W158-R160 PolarHBondContact O-N 3.49Å; W158-T163 PolarHBondContact O-OG1 3.09Å
159	E	84.6	Confident	91.7	Very high	9 Å²	9	46.8 Å²	46.8	4%	0.042	22%	0.222	C	C	.	.			trans	-51.7	91.5	173.5	-67.4	158.6	-121.2	0	0	111.1	Q88 H92 K101 Y102 N156	Q88-E159 PolarHBondContact NE2-OE1 3.07Å; Q88-E159 VanDerWaalsContact NE2-OE1 3.13Å; Q88-E159 VanDerWaalsContact OE1-CD 3.3Å; Q88-E159 PolarHBondContact OE1-OE1 2.72Å; Q88-E159 PolarHBondContact OE1-OE2 2.84Å; H92-E159 IonicContact CD2-OE2 3.9Å; H92-E159 IonicContact CE1-OE2 2.71Å; H92-E159 IonicContact NE2-OE2 2.76Å; H92-E159 PolarHBondContact NE2-OE2 3.15Å; K101-E159 IonicContact NZ-OE1 3.31Å; K101-E159 PolarHBondContact NZ-OE1 3.24Å; Y102-E159 HydrophobicContact CE1-CB 4.43Å; Y102-E159 WeakPolarHBondContact CE2-OE2 3.14Å; Y102-E159 VanDerWaalsContact CZ-OE2 3.23Å; Y102-E159 WeakPolarHBondContact OH-CB 3.23Å; Y102-E159 PolarHBondContact OH-OE1 3.29Å; Y102-E159 VanDerWaalsContact OH-OE1 3.08Å; Y102-E159 PolarHBondContact OH-OE2 3.36Å; N156-E159 WeakPolarHBondContact O-CG 3.18Å
160	R	87.6	Confident	91.7	Very high	74 Å²	74	47.9 Å²	47.9	28%	0.279	23%	0.232	S	C	.	.			trans	-135.8	153.4	173.9	-66.5	-64.3	178.1	147.5	-4.8	110.1	L105 W158 Y162 T163 L164	L105-R160 VanDerWaalsContact CD1-NH1 3.35Å; W158-R160 HydrophobicContact CG-CG 4.27Å; W158-R160 PolarHBondContact O-N 3.49Å; R160-Y162 VanDerWaalsContact C-N 3.27Å; R160-Y162 HydrophobicContact CB-CD1 3.96Å; R160-Y162 HydrophobicContact CB-CE1 3.59Å; R160-Y162 HydrophobicContact CG-CE1 3.97Å; R160-Y162 PolarHBondContact O-N 3Å; R160-T163 PolarHBondContact N-OG1 3.16Å; R160-T163 PolarHBondContact O-N 3.12Å; R160-T163 VanDerWaalsContact O-N 3.08Å; R160-T163 PolarHBondContact O-OG1 3.27Å; R160-L164 WeakPolarHBondContact O-CB 3.4Å; R160-L164 PolarHBondContact O-N 3.22Å
161	Y	86.2	Confident	91.7	Very high	120 Å²	120	47.7 Å²	47.7	47%	0.471	23%	0.231	S	C	.	.	H	α-helix	trans	-50.1	-45.9	179.3	-177.3	-103.6	0	0	0	113.6	K113 T163 V165	K113-Y161 HydrophobicContact CD-CE2 3.6Å; Y161-T163 PolarHBondContact O-N 3.22Å; Y161-V165 HydrophobicContact CD2-CG2 3.79Å; Y161-V165 HydrophobicContact CE2-CB 4.49Å; Y161-V165 HydrophobicContact CE2-CG2 3.75Å; Y161-V165 WeakPolarHBondContact O-CB 3.26Å; Y161-V165 WeakPolarHBondContact O-CG2 3.37Å; Y161-V165 PolarHBondContact O-N 2.99Å
162	Y	87.9	Confident	91.6	Very high	156 Å²	156	43.3 Å²	43.3	61%	0.612	21%	0.208	S	C	*	.	H	α-helix	trans	-79.9	-10.1	-176.2	64.5	-92.8	0	0	0	114.6	R160 P166	R160-Y162 VanDerWaalsContact C-N 3.27Å; R160-Y162 HydrophobicContact CB-CD1 3.96Å; R160-Y162 HydrophobicContact CB-CE1 3.59Å; R160-Y162 HydrophobicContact CG-CE1 3.97Å; R160-Y162 PolarHBondContact O-N 3Å; Y162-P166 WeakPolarHBondContact O-CG 3.45Å
163	T	91.6	Very high	91.6	Very high	35 Å²	35	45.6 Å²	45.6	22%	0.215	22%	0.222	C	C	.	.	H	α-helix	trans	-101.2	-49.2	174.4	49.4	0	0	0	0	111.1	W158 R160 Y161 S167	W158-T163 PolarHBondContact O-OG1 3.09Å; R160-T163 PolarHBondContact N-OG1 3.16Å; R160-T163 PolarHBondContact O-N 3.12Å; R160-T163 VanDerWaalsContact O-N 3.08Å; R160-T163 PolarHBondContact O-OG1 3.27Å; Y161-T163 PolarHBondContact O-N 3.22Å; T163-S167 PolarHBondContact O-N 2.97Å; T163-S167 PolarHBondContact O-OG 2.99Å
164	L	90.3	Very high	91.7	Very high	1 Å²	1	45.4 Å²	45.4	1%	0.005	22%	0.221	C	C	.	.	H	α-helix	trans	-78.5	-36.4	-169.9	-165.7	67.1	0	0	0	113.3	I110 M114 F152 R160 S167 A168	I110-L164 HydrophobicContact CG2-CD2 3.94Å; M114-L164 HydrophobicContact CG-CG 4.4Å; M114-L164 HydrophobicContact SD-CD1 4.09Å; M114-L164 HydrophobicContact SD-CD2 3.77Å; M114-L164 HydrophobicContact SD-CG 3.88Å; F152-L164 HydrophobicContact CD2-CD1 4.46Å; F152-L164 HydrophobicContact CE2-CD1 3.88Å; F152-L164 HydrophobicContact CZ-CD1 4.47Å; R160-L164 WeakPolarHBondContact O-CB 3.4Å; R160-L164 PolarHBondContact O-N 3.22Å; L164-S167 PolarHBondContact O-OG 3.38Å; L164-S167 VanDerWaalsContact O-OG 3.08Å; L164-A168 WeakPolarHBondContact O-CB 3.37Å; L164-A168 PolarHBondContact O-N 3.48Å
165	V	91.6	Very high	91.7	Very high	22 Å²	22	44.1 Å²	44.1	13%	0.133	21%	0.209	C	C	.	.	H	α-helix	trans	-70.5	-43.9	179.2	-180	0	0	0	0	111.8	K113 Y161 S167 A168 V169	K113-V165 HydrophobicContact CB-CG2 4.14Å; Y161-V165 HydrophobicContact CD2-CG2 3.79Å; Y161-V165 HydrophobicContact CE2-CB 4.49Å; Y161-V165 HydrophobicContact CE2-CG2 3.75Å; Y161-V165 WeakPolarHBondContact O-CB 3.26Å; Y161-V165 WeakPolarHBondContact O-CG2 3.37Å; Y161-V165 PolarHBondContact O-N 2.99Å; V165-S167 PolarHBondContact O-N 3.45Å; V165-A168 PolarHBondContact O-N 3.14Å; V165-V169 WeakPolarHBondContact O-CG2 3.35Å; V165-V169 PolarHBondContact O-N 3.26Å
166	P	94.8	Very high	91.8	Very high	76 Å²	76	43 Å²	43	49%	0.494	20%	0.203	S	C	.	.	H	α-helix	trans	-62.7	-39	173.8	-26.7	38.1	0	0	0	113.9	Y162 V169 A170	Y162-P166 WeakPolarHBondContact O-CG 3.45Å; P166-V169 PolarHBondContact O-N 3.3Å; P166-A170 WeakPolarHBondContact O-CB 3.49Å; P166-A170 PolarHBondContact O-N 3.02Å
167	S	94.4	Very high	92	Very high	3 Å²	3	42.9 Å²	42.9	2%	0.021	20%	0.202	C	C	.	.	H	α-helix	trans	-70.6	-34.2	177.2	62.9	0	0	0	0	112.6	T155 T163 L164 V165 A170 I171	T155-S167 WeakPolarHBondContact OG1-CB 3.38Å; T155-S167 PolarHBondContact OG1-OG 2.87Å; T163-S167 PolarHBondContact O-N 2.97Å; T163-S167 PolarHBondContact O-OG 2.99Å; L164-S167 PolarHBondContact O-OG 3.38Å; L164-S167 VanDerWaalsContact O-OG 3.08Å; V165-S167 PolarHBondContact O-N 3.45Å; S167-A170 WeakPolarHBondContact O-CB 3.3Å; S167-A170 PolarHBondContact O-N 3.06Å; S167-I171 PolarHBondContact O-N 3.34Å
168	A	93.6	Very high	92.2	Very high	0 Å²	0	38.7 Å²	38.7	0%	0	19%	0.185	C	C	.	.	H	α-helix	trans	-63.1	-42.9	171.2	0	0	0	0	0	112.7	M114 I118 L164 V165 A170 I171 G172	M114-A168 HydrophobicContact CB-CB 4.26Å; M114-A168 HydrophobicContact CG-CB 3.73Å; I118-A168 HydrophobicContact CD1-CB 4.41Å; I118-A168 HydrophobicContact CG1-CB 4.03Å; L164-A168 WeakPolarHBondContact O-CB 3.37Å; L164-A168 PolarHBondContact O-N 3.48Å; V165-A168 PolarHBondContact O-N 3.14Å; A168-A170 VanDerWaalsContact C-N 3.34Å; A168-I171 PolarHBondContact O-N 3.17Å; A168-G172 PolarHBondContact O-N 2.78Å
169	V	94.9	Very high	92.6	Very high	58 Å²	58	33.1 Å²	33.1	35%	0.352	16%	0.164	S	C	.	.	H	α-helix	trans	-62.4	-42	171.3	170.8	0	0	0	0	110.5	T121 V165 P166 I171 G172 V173	T121-V169 HydrophobicContact CG2-CG1 4.29Å; V165-V169 WeakPolarHBondContact O-CG2 3.35Å; V165-V169 PolarHBondContact O-N 3.26Å; P166-V169 PolarHBondContact O-N 3.3Å; V169-I171 PolarHBondContact O-N 2.91Å; V169-G172 CarbonylContact O-C 3.56Å; V169-G172 WeakPolarHBondContact O-CA 3.37Å; V169-G172 PolarHBondContact O-N 3.5Å; V169-V173 WeakPolarHBondContact O-CG2 3.43Å; V169-V173 PolarHBondContact O-N 3.09Å
170	A	95.3	Very high	93	Very high	29 Å²	29	32.7 Å²	32.7	24%	0.24	16%	0.162	C	C	.	.	H	α-helix	trans	-62	-40.8	176.7	0	0	0	0	0	112.9	I148 P166 S167 A168 G172 V173 A174	I148-A170 HydrophobicContact CG2-CB 3.75Å; I148-A170 WeakPolarHBondContact CG2-O 3.4Å; P166-A170 WeakPolarHBondContact O-CB 3.49Å; P166-A170 PolarHBondContact O-N 3.02Å; S167-A170 WeakPolarHBondContact O-CB 3.3Å; S167-A170 PolarHBondContact O-N 3.06Å; A168-A170 VanDerWaalsContact C-N 3.34Å; A170-G172 VanDerWaalsContact C-N 3.33Å; A170-V173 WeakPolarHBondContact O-CB 3.3Å; A170-V173 PolarHBondContact O-N 2.94Å; A170-V173 VanDerWaalsContact O-N 3.16Å; A170-A174 WeakPolarHBondContact O-CB 3.43Å; A170-A174 PolarHBondContact O-N 3.36Å
171	I	95.1	Very high	93.3	Very high	0 Å²	0	29.2 Å²	29.2	0%	0	15%	0.149	C	C	.	.	H	α-helix	trans	-59.3	-45.6	169.1	-75.5	-175.1	0	0	0	110.7	Y81 I118 I148 Y149 F152 S167 A168 V169 V173 A174 I175	Y81-I171 HydrophobicContact CD2-CD1 3.88Å; Y81-I171 HydrophobicContact CE2-CD1 3.66Å; Y81-I171 HydrophobicContact CE2-CG2 4.3Å; I118-I171 HydrophobicContact CG1-CG2 4.38Å; I148-I171 HydrophobicContact CG2-CG1 4.35Å; Y149-I171 HydrophobicContact CD1-CD1 3.89Å; Y149-I171 HydrophobicContact CD1-CG1 4.24Å; Y149-I171 HydrophobicContact CE1-CD1 4.08Å; Y149-I171 HydrophobicContact CE1-CG1 4.34Å; Y149-I171 HydrophobicContact CE1-CG2 4.07Å; F152-I171 HydrophobicContact CB-CD1 3.38Å; F152-I171 HydrophobicContact CB-CG1 3.96Å; F152-I171 HydrophobicContact CD1-CD1 3.52Å; F152-I171 HydrophobicContact CD2-CD1 3.75Å; F152-I171 HydrophobicContact CE1-CD1 4.2Å; F152-I171 HydrophobicContact CE2-CD1 4.4Å; F152-I171 HydrophobicContact CG-CD1 3.26Å; F152-I171 HydrophobicContact CG-CG1 4.23Å; S167-I171 PolarHBondContact O-N 3.34Å; A168-I171 PolarHBondContact O-N 3.17Å; V169-I171 PolarHBondContact O-N 2.91Å; I171-V173 PolarHBondContact O-N 2.79Å; I171-A174 PolarHBondContact O-N 2.93Å; I171-I175 WeakPolarHBondContact O-CB 3.02Å; I171-I175 PolarHBondContact O-N 3.32Å
172	G	93.9	Very high	93.7	Very high	0 Å²	0	23.5 Å²	23.5	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-59.1	-31.4	176.1	0	0	0	0	0	113.1	P122 A168 V169 A170	P122-G172 WeakPolarHBondContact CD-O 3.23Å; P122-G172 WeakPolarHBondContact CG-O 3.5Å; A168-G172 PolarHBondContact O-N 2.78Å; V169-G172 CarbonylContact O-C 3.56Å; V169-G172 WeakPolarHBondContact O-CA 3.37Å; V169-G172 PolarHBondContact O-N 3.5Å; A170-G172 VanDerWaalsContact C-N 3.33Å
173	V	94.4	Very high	93.9	Very high	49 Å²	49	16.5 Å²	16.5	30%	0.297	10%	0.102	S	C	.	.	H	α-helix	trans	-69.2	-46.4	169.2	178.1	0	0	0	0	111	T121 Y128 V169 A170 I171 P177	T121-V173 HydrophobicContact CG2-CB 4.39Å; T121-V173 HydrophobicContact CG2-CG2 3.51Å; Y128-V173 HydrophobicContact CD2-CG1 4.36Å; Y128-V173 HydrophobicContact CE2-CG1 3.69Å; Y128-V173 VanDerWaalsContact CE2-O 3.3Å; Y128-V173 WeakPolarHBondContact CE2-O 3.45Å; Y128-V173 VanDerWaalsContact OH-CA 3.25Å; Y128-V173 WeakPolarHBondContact OH-CA 3.3Å; Y128-V173 PolarHBondContact OH-O 3.24Å; V169-V173 WeakPolarHBondContact O-CG2 3.43Å; V169-V173 PolarHBondContact O-N 3.09Å; A170-V173 WeakPolarHBondContact O-CB 3.3Å; A170-V173 PolarHBondContact O-N 2.94Å; A170-V173 VanDerWaalsContact O-N 3.16Å; I171-V173 PolarHBondContact O-N 2.79Å; V173-P177 WeakPolarHBondContact O-CD 3.5Å; V173-P177 WeakPolarHBondContact O-CG 3.4Å
174	A	94.8	Very high	93.9	Very high	1 Å²	1	14.8 Å²	14.8	1%	0.008	9%	0.091	C	C	.	.	H	α-helix	trans	-80.1	-26.1	-169.3	0	0	0	0	0	115.5	A145 I148 A170 I171 V176 P177 F178	A145-A174 HydrophobicContact CB-CB 4.21Å; I148-A174 HydrophobicContact CB-CB 4.15Å; I148-A174 HydrophobicContact CD1-CB 3.86Å; I148-A174 HydrophobicContact CG2-CB 3.92Å; A170-A174 WeakPolarHBondContact O-CB 3.43Å; A170-A174 PolarHBondContact O-N 3.36Å; I171-A174 PolarHBondContact O-N 2.93Å; A174-V176 PolarHBondContact O-N 3.13Å; A174-P177 WeakPolarHBondContact O-CD 3.35Å; A174-F178 VanDerWaalsContact O-CB 3.23Å; A174-F178 WeakPolarHBondContact O-CB 3.38Å; A174-F178 PolarHBondContact O-N 3.41Å
175	I	93.9	Very high	94	Very high	28 Å²	28	14.8 Å²	14.8	14%	0.144	9%	0.091	C	C	.	.	H	α-helix	trans	-62.7	-45.2	-169.7	-171.3	166.2	0	0	0	113.2	P122 Y149 I171 W179	P122-I175 HydrophobicContact CB-CG2 4.26Å; P122-I175 HydrophobicContact CG-CG2 3.64Å; Y149-I175 WeakPolarHBondContact OH-CG1 3.49Å; I171-I175 WeakPolarHBondContact O-CB 3.02Å; I171-I175 PolarHBondContact O-N 3.32Å; I175-W179 PolarHBondContact O-N 3.08Å
176	V	94.6	Very high	94.1	Very high	3 Å²	3	13.8 Å²	13.8	2%	0.018	9%	0.085	C	C	.	.	H	α-helix	trans	-69	-48.5	178.1	176.9	0	0	0	0	111.6	P122 T129 A174 F178 W179 A180 H478 W479 A482	P122-V176 HydrophobicContact CB-CG2 3.98Å; T129-V176 HydrophobicContact CG2-CG1 4.4Å; A174-V176 PolarHBondContact O-N 3.13Å; V176-F178 VanDerWaalsContact C-N 3.34Å; V176-F178 PolarHBondContact O-N 3.26Å; V176-W179 PolarHBondContact O-N 3.31Å; V176-A180 VanDerWaalsContact O-CB 3.27Å; V176-A180 WeakPolarHBondContact O-CB 3.48Å; V176-A180 PolarHBondContact O-N 3.48Å; V176-H478 HydrophobicContact CG1-CB 4.28Å; V176-W479 HydrophobicContact CG1-CB 4.4Å; V176-A482 HydrophobicContact CG2-CB 3.73Å
177	P	95.1	Very high	94	Very high	0 Å²	0	10.1 Å²	10.1	0%	0	6%	0.062	C	C	.	.	H	α-helix	trans	-56.8	-39.5	171.8	-23.4	28.5	0	0	0	114.9	Y128 T129 M141 V173 A174 A180 S181	Y128-P177 HydrophobicContact CE2-CG 3.86Å; T129-P177 HydrophobicContact CG2-CB 3.96Å; T129-P177 HydrophobicContact CG2-CG 3.83Å; T129-P177 WeakPolarHBondContact OG1-CD 3.5Å; T129-P177 WeakPolarHBondContact OG1-CG 3.33Å; M141-P177 HydrophobicContact CE-CB 3.79Å; M141-P177 HydrophobicContact CG-CB 3.89Å; M141-P177 HydrophobicContact SD-CB 3.62Å; V173-P177 WeakPolarHBondContact O-CD 3.5Å; V173-P177 WeakPolarHBondContact O-CG 3.4Å; A174-P177 WeakPolarHBondContact O-CD 3.35Å; P177-A180 PolarHBondContact O-N 3Å; P177-S181 VanDerWaalsContact O-CB 3.27Å; P177-S181 WeakPolarHBondContact O-CB 3.42Å; P177-S181 PolarHBondContact O-N 3.47Å; P177-S181 PolarHBondContact O-OG 3.2Å
178	F	95.3	Very high	93.8	Very high	0 Å²	0	10 Å²	10	0%	0	6%	0.061	C	C	.	.	H	α-helix	trans	-59.2	-53	177.9	178.9	-112.1	0	0	0	110.9	A74 V77 A145 Y149 A174 V176 S181 L182 F305	A74-F178 HydrophobicContact CB-CZ 4.32Å; V77-F178 HydrophobicContact CG1-CZ 4.31Å; A145-F178 HydrophobicContact CB-CB 3.76Å; A145-F178 HydrophobicContact CB-CD2 3.72Å; A145-F178 HydrophobicContact CB-CG 4.13Å; Y149-F178 HydrophobicContact CE2-CB 4.49Å; Y149-F178 HydrophobicContact CE2-CD1 4.19Å; Y149-F178 HydrophobicContact CE2-CG 4.23Å; A174-F178 VanDerWaalsContact O-CB 3.23Å; A174-F178 WeakPolarHBondContact O-CB 3.38Å; A174-F178 PolarHBondContact O-N 3.41Å; V176-F178 VanDerWaalsContact C-N 3.34Å; V176-F178 PolarHBondContact O-N 3.26Å; F178-S181 PolarHBondContact O-OG 3.29Å; F178-L182 HydrophobicContact CE1-CD2 4.32Å; F178-L182 HydrophobicContact CZ-CD2 4.37Å; F178-L182 WeakPolarHBondContact O-CB 3.24Å; F178-L182 PolarHBondContact O-N 3.15Å; F178-F305 HydrophobicContact CE2-CE2 4.28Å; F178-F305 HydrophobicContact CE2-CZ 4.15Å; F178-F305 HydrophobicContact CZ-CZ 4.38Å
179	W	94.6	Very high	93.7	Very high	32 Å²	32	10 Å²	10	12%	0.121	6%	0.061	C	C	.	.	H	α-helix	trans	-66.6	-40.2	179.7	-79.3	110.4	0	0	0	112.9	Y78 I175 V176 L182 G183 F226 F230 H478	Y78-W179 HydrophobicContact CD2-CZ2 4.18Å; Y78-W179 HydrophobicContact CE2-CZ2 4.29Å; I175-W179 PolarHBondContact O-N 3.08Å; V176-W179 PolarHBondContact O-N 3.31Å; W179-L182 HydrophobicContact CE3-CD2 4.08Å; W179-L182 HydrophobicContact CZ3-CD2 3.92Å; W179-L182 PolarHBondContact O-N 2.88Å; W179-G183 PolarHBondContact O-N 3.45Å; W179-F226 HydrophobicContact CZ3-CE1 4.47Å; W179-F226 HydrophobicContact CZ3-CZ 4.15Å; W179-F230 HydrophobicContact CH2-CD1 4.27Å; W179-F230 AromaticContact CH2-CD2 3.86Å; W179-F230 HydrophobicContact CH2-CD2 3.86Å; W179-F230 AromaticContact CH2-CE1 3.86Å; W179-F230 HydrophobicContact CH2-CE1 3.86Å; W179-F230 AromaticContact CH2-CE2 3.42Å; W179-F230 HydrophobicContact CH2-CE2 3.42Å; W179-F230 VanDerWaalsContact CH2-CE2 3.42Å; W179-F230 HydrophobicContact CH2-CG 4.28Å; W179-F230 AromaticContact CH2-CZ 3.43Å; W179-F230 HydrophobicContact CH2-CZ 3.43Å; W179-F230 VanDerWaalsContact CH2-CZ 3.43Å; W179-F230 AromaticContact CZ2-CE2 3.8Å; W179-F230 HydrophobicContact CZ2-CE2 3.8Å; W179-F230 AromaticContact CZ2-CZ 3.76Å; W179-F230 HydrophobicContact CZ2-CZ 3.76Å; W179-H478 VanDerWaalsContact C-CD2 3.43Å; W179-H478 HydrophobicContact CB-CB 4.15Å; W179-H478 PolarHBondContact O-NE2 3.24Å
180	A	93.9	Very high	93.6	Very high	0 Å²	0	7.2 Å²	7.2	0%	0	4%	0.044	C	C	.	.	H	α-helix	trans	-65.7	-43.3	178.1	0	0	0	0	0	113.3	T129 I133 V176 P177 S184	T129-A180 HydrophobicContact CG2-CB 4.31Å; I133-A180 HydrophobicContact CD1-CB 3.87Å; V176-A180 VanDerWaalsContact O-CB 3.27Å; V176-A180 WeakPolarHBondContact O-CB 3.48Å; V176-A180 PolarHBondContact O-N 3.48Å; P177-A180 PolarHBondContact O-N 3Å; A180-S184 WeakPolarHBondContact O-CB 3.42Å; A180-S184 PolarHBondContact O-N 3.1Å; A180-S184 VanDerWaalsContact O-N 3.15Å; A180-S184 PolarHBondContact O-OG 2.87Å
181	S	93.5	Very high	93.2	Very high	0 Å²	0	5.9 Å²	5.9	0%	0	3%	0.032	C	C	.	.	H	α-helix	trans	-66.9	-42.5	175.1	55.9	0	0	0	0	111.4	I138 M142 P177 F178 S184 Y185	I138-S181 VanDerWaalsContact CG2-O 3.27Å; I138-S181 WeakPolarHBondContact CG2-O 3.45Å; M142-S181 VanDerWaalsContact CG-OG 3.3Å; M142-S181 WeakPolarHBondContact CG-OG 3.45Å; P177-S181 VanDerWaalsContact O-CB 3.27Å; P177-S181 WeakPolarHBondContact O-CB 3.42Å; P177-S181 PolarHBondContact O-N 3.47Å; P177-S181 PolarHBondContact O-OG 3.2Å; F178-S181 PolarHBondContact O-OG 3.29Å; S181-S184 PolarHBondContact O-N 3.33Å; S181-Y185 VanDerWaalsContact O-CB 3.27Å; S181-Y185 WeakPolarHBondContact O-CB 3.4Å; S181-Y185 PolarHBondContact O-N 3.41Å
182	L	93.8	Very high	92.9	Very high	1 Å²	1	6.4 Å²	6.4	1%	0.005	4%	0.035	C	C	.	.	H	α-helix	trans	-62.1	-47.2	177.3	-170.8	67.3	0	0	0	112.6	A74 M142 F178 W179 S184 Y185 I186 F226	A74-L182 HydrophobicContact CB-CD1 4.2Å; A74-L182 HydrophobicContact CB-CD2 3.66Å; M142-L182 HydrophobicContact CE-CD1 3.64Å; F178-L182 HydrophobicContact CE1-CD2 4.32Å; F178-L182 HydrophobicContact CZ-CD2 4.37Å; F178-L182 WeakPolarHBondContact O-CB 3.24Å; F178-L182 PolarHBondContact O-N 3.15Å; W179-L182 HydrophobicContact CE3-CD2 4.08Å; W179-L182 HydrophobicContact CZ3-CD2 3.92Å; W179-L182 PolarHBondContact O-N 2.88Å; L182-S184 VanDerWaalsContact C-N 3.35Å; L182-S184 PolarHBondContact O-N 3.04Å; L182-Y185 WeakPolarHBondContact O-CB 3.44Å; L182-Y185 PolarHBondContact O-N 2.99Å; L182-I186 WeakPolarHBondContact O-CG1 3.41Å; L182-I186 PolarHBondContact O-N 3.2Å; L182-I186 VanDerWaalsContact O-N 3.08Å; L182-F226 HydrophobicContact CD1-CE2 4.07Å; L182-F226 HydrophobicContact CD2-CE2 3.73Å; L182-F226 HydrophobicContact CD2-CZ 3.52Å; L182-F226 HydrophobicContact CG-CE2 3.89Å; L182-F226 HydrophobicContact CG-CZ 3.95Å
183	G	92.2	Very high	92.7	Very high	8 Å²	8	7.6 Å²	7.6	8%	0.082	4%	0.04	C	C	.	.	H	α-helix	trans	-62.6	-39.6	177.5	0	0	0	0	0	113.4	W179 T187 Y474	W179-G183 PolarHBondContact O-N 3.45Å; G183-T187 PolarHBondContact O-N 2.84Å; G183-T187 PolarHBondContact O-OG1 3.33Å; G183-Y474 WeakPolarHBondContact O-CE2 3.35Å
184	S	91.9	Very high	92.5	Very high	0 Å²	0	5.6 Å²	5.6	0%	0	3%	0.027	C	C	.	.	H	α-helix	trans	-67.6	-43.2	173.8	-55	0	0	0	0	111.6	A180 S181 L182 I186 T187 R188 D471	A180-S184 WeakPolarHBondContact O-CB 3.42Å; A180-S184 PolarHBondContact O-N 3.1Å; A180-S184 VanDerWaalsContact O-N 3.15Å; A180-S184 PolarHBondContact O-OG 2.87Å; S181-S184 PolarHBondContact O-N 3.33Å; L182-S184 VanDerWaalsContact C-N 3.35Å; L182-S184 PolarHBondContact O-N 3.04Å; S184-I186 PolarHBondContact O-N 3.38Å; S184-T187 PolarHBondContact O-N 3.43Å; S184-R188 WeakPolarHBondContact O-CB 3.3Å; S184-R188 PolarHBondContact O-N 2.85Å; S184-D471 WeakPolarHBondContact CB-OD1 3.36Å; S184-D471 WeakPolarHBondContact OG-CA 3.23Å; S184-D471 PolarHBondContact OG-OD1 2.94Å
185	Y	93.3	Very high	92	Very high	0 Å²	0	6 Å²	6	0%	0	3%	0.029	C	C	.	.	H	α-helix	trans	-57.3	-51.9	178.7	-169.8	-96.8	0	0	0	112.2	N66 I138 M142 S181 L182 T187 R188 M189 C309 G310 A312	N66-Y185 HydrophobicContact CB-CE1 4.46Å; I138-Y185 HydrophobicContact CG2-CD2 3.83Å; I138-Y185 HydrophobicContact CG2-CG 4.31Å; M142-Y185 HydrophobicContact CE-CD1 4.25Å; M142-Y185 HydrophobicContact CE-CG 4.19Å; M142-Y185 HydrophobicContact SD-CD1 4.42Å; M142-Y185 HydrophobicContact SD-CD2 3.9Å; M142-Y185 HydrophobicContact SD-CG 3.77Å; S181-Y185 VanDerWaalsContact O-CB 3.27Å; S181-Y185 WeakPolarHBondContact O-CB 3.4Å; S181-Y185 PolarHBondContact O-N 3.41Å; L182-Y185 WeakPolarHBondContact O-CB 3.44Å; L182-Y185 PolarHBondContact O-N 2.99Å; Y185-T187 VanDerWaalsContact C-N 3.34Å; Y185-T187 PolarHBondContact O-N 3.45Å; Y185-R188 PolarHBondContact O-N 3.35Å; Y185-M189 HydrophobicContact CD1-CG 4.07Å; Y185-M189 HydrophobicContact CE1-CE 4.4Å; Y185-M189 HydrophobicContact CE1-CG 3.84Å; Y185-M189 HydrophobicContact CE1-SD 4.45Å; Y185-M189 HydrophobicContact CE2-CE 3.95Å; Y185-M189 WeakPolarHBondContact O-CB 3.39Å; Y185-M189 VanDerWaalsContact O-CG 3.23Å; Y185-M189 WeakPolarHBondContact O-CG 3.35Å; Y185-M189 PolarHBondContact O-N 3.42Å; Y185-C309 WeakPolarHBondContact OH-CB 3.13Å; Y185-G310 WeakPolarHBondContact CE2-O 3.42Å; Y185-G310 PolarHBondContact OH-N 3.1Å; Y185-G310 PolarHBondContact OH-O 3.04Å; Y185-A312 HydrophobicContact CD2-CB 3.66Å; Y185-A312 HydrophobicContact CE2-CB 3.83Å
186	I	93.6	Very high	91.6	Very high	1 Å²	1	6.6 Å²	6.6	1%	0.005	3%	0.029	C	C	.	.	H	α-helix	trans	-62.7	-42.5	-178.2	-62.4	-66.8	0	0	0	110.9	V67 S70 L182 S184 A190 F222 Q223 F226	V67-I186 HydrophobicContact CG1-CD1 4.08Å; S70-I186 WeakPolarHBondContact OG-CD1 3.44Å; L182-I186 WeakPolarHBondContact O-CG1 3.41Å; L182-I186 PolarHBondContact O-N 3.2Å; L182-I186 VanDerWaalsContact O-N 3.08Å; S184-I186 PolarHBondContact O-N 3.38Å; I186-A190 PolarHBondContact O-N 3.25Å; I186-F222 HydrophobicContact CG2-CB 4.31Å; I186-Q223 HydrophobicContact CG2-CG 4.44Å; I186-F226 HydrophobicContact CD1-CB 4.27Å; I186-F226 HydrophobicContact CD1-CD2 3.79Å; I186-F226 HydrophobicContact CD1-CG 4.21Å; I186-F226 HydrophobicContact CG1-CB 4.4Å; I186-F226 HydrophobicContact CG1-CD2 3.89Å; I186-F226 HydrophobicContact CG1-CE2 4.47Å; I186-F226 HydrophobicContact CG1-CG 4.07Å; I186-F226 HydrophobicContact CG2-CB 4.18Å
187	T	92.3	Very high	91.2	Very high	0 Å²	0	7.7 Å²	7.7	0%	0	4%	0.038	C	C	.	.	H	α-helix	trans	-71	-38.3	179.5	-52.2	0	0	0	0	111.9	G183 S184 Y185 A190 Q191 I219 Q223 L470 Y474	G183-T187 PolarHBondContact O-N 2.84Å; G183-T187 PolarHBondContact O-OG1 3.33Å; S184-T187 PolarHBondContact O-N 3.43Å; Y185-T187 VanDerWaalsContact C-N 3.34Å; Y185-T187 PolarHBondContact O-N 3.45Å; T187-A190 WeakPolarHBondContact O-CB 3.38Å; T187-A190 PolarHBondContact O-N 2.89Å; T187-Q191 PolarHBondContact O-N 3.46Å; T187-I219 HydrophobicContact CG2-CD1 4.29Å; T187-I219 HydrophobicContact CG2-CG1 4.35Å; T187-I219 HydrophobicContact CG2-CG2 4.33Å; T187-Q223 PolarHBondContact OG1-NE2 2.97Å; T187-L470 HydrophobicContact CG2-CD1 3.99Å; T187-L470 HydrophobicContact CG2-CD2 4Å; T187-Y474 PolarHBondContact OG1-OH 2.91Å
188	R	90.4	Very high	90.7	Very high	0 Å²	0	9.8 Å²	9.8	0%	0	5%	0.05	C	C	.	.	H	α-helix	trans	-67.6	-39.2	176	-172.3	63.7	179.8	127.8	4	111.9	S184 Y185 A190 Q191 Q192 E195 A312 Y313 E317 L470	S184-R188 WeakPolarHBondContact O-CB 3.3Å; S184-R188 PolarHBondContact O-N 2.85Å; Y185-R188 PolarHBondContact O-N 3.35Å; R188-A190 VanDerWaalsContact C-N 3.32Å; R188-A190 PolarHBondContact O-N 3.08Å; R188-Q191 VanDerWaalsContact CD-OE1 3.3Å; R188-Q191 WeakPolarHBondContact O-CB 3.25Å; R188-Q191 PolarHBondContact O-N 3.1Å; R188-Q192 WeakPolarHBondContact O-CG 3.24Å; R188-Q192 PolarHBondContact O-N 3.35Å; R188-E195 IonicContact NH1-OE1 2.72Å; R188-A312 HydrophobicContact CG-CB 4.43Å; R188-A312 WeakPolarHBondContact CG-O 3.47Å; R188-Y313 HydrophobicContact CG-CE1 4.37Å; R188-E317 IonicContact CZ-OE1 3.37Å; R188-E317 IonicContact CZ-OE2 2.72Å; R188-E317 IonicContact NH2-OE1 3.19Å; R188-E317 PolarHBondContact NH2-OE1 2.93Å; R188-E317 IonicContact NH2-OE2 2.76Å; R188-E317 PolarHBondContact NH2-OE2 3.22Å; R188-L470 HydrophobicContact CB-CD2 4.49Å
189	M	91.3	Very high	89.8	Confident	0 Å²	0	11.6 Å²	11.6	0%	0	6%	0.057	C	C	.	.	H	α-helix	trans	-62.5	-36.8	171.4	-74.2	-78	141.9	0	0	111.9	V63 N66 V67 Y185 Q192 Y193 P311 A312	V63-M189 HydrophobicContact CB-SD 4.5Å; V63-M189 HydrophobicContact CG1-CB 4.04Å; V63-M189 VanDerWaalsContact CG1-O 3.3Å; V63-M189 WeakPolarHBondContact CG1-O 3.48Å; V63-M189 HydrophobicContact CG1-SD 3.96Å; V63-M189 HydrophobicContact CG2-SD 4.41Å; N66-M189 HydrophobicContact CB-SD 3.82Å; V67-M189 HydrophobicContact CG2-CB 3.5Å; V67-M189 HydrophobicContact CG2-CG 4.04Å; Y185-M189 HydrophobicContact CD1-CG 4.07Å; Y185-M189 HydrophobicContact CE1-CE 4.4Å; Y185-M189 HydrophobicContact CE1-CG 3.84Å; Y185-M189 HydrophobicContact CE1-SD 4.45Å; Y185-M189 HydrophobicContact CE2-CE 3.95Å; Y185-M189 WeakPolarHBondContact O-CB 3.39Å; Y185-M189 VanDerWaalsContact O-CG 3.23Å; Y185-M189 WeakPolarHBondContact O-CG 3.35Å; Y185-M189 PolarHBondContact O-N 3.42Å; M189-Q192 PolarHBondContact O-N 2.85Å; M189-Y193 WeakPolarHBondContact O-CB 3.17Å; M189-Y193 PolarHBondContact O-N 3.15Å; M189-P311 VanDerWaalsContact CE-O 3.32Å; M189-P311 WeakPolarHBondContact CE-O 3.3Å; M189-A312 HydrophobicContact CE-CB 4.29Å
190	A	91.5	Very high	88.7	Confident	0 Å²	0	15.8 Å²	15.8	0%	0	8%	0.076	C	C	.	.	H	α-helix	trans	-65.4	-38.6	173.3	0	0	0	0	0	112.7	I186 T187 R188 Y193 Y194 I219 F222	I186-A190 PolarHBondContact O-N 3.25Å; T187-A190 WeakPolarHBondContact O-CB 3.38Å; T187-A190 PolarHBondContact O-N 2.89Å; R188-A190 VanDerWaalsContact C-N 3.32Å; R188-A190 PolarHBondContact O-N 3.08Å; A190-Y193 PolarHBondContact O-N 3.24Å; A190-Y194 PolarHBondContact O-N 3.38Å; A190-Y194 VanDerWaalsContact O-N 3.09Å; A190-I219 HydrophobicContact CB-CB 4.46Å; A190-I219 HydrophobicContact CB-CG1 3.88Å; A190-F222 VanDerWaalsContact CA-CD2 3.5Å; A190-F222 HydrophobicContact CB-CB 4.13Å; A190-F222 HydrophobicContact CB-CD2 3.62Å; A190-F222 HydrophobicContact CB-CE2 4.3Å; A190-F222 HydrophobicContact CB-CG 4.07Å
191	Q	88.4	Confident	87.6	Confident	0 Å²	0	18.9 Å²	18.9	0%	0	9%	0.09	C	C	.	.	H	α-helix	trans	-64.5	-46.7	172.2	-70	170.3	-23.6	0	0	112.1	T187 R188 Y193 Y194 E195 A464	T187-Q191 PolarHBondContact O-N 3.46Å; R188-Q191 VanDerWaalsContact CD-OE1 3.3Å; R188-Q191 WeakPolarHBondContact O-CB 3.25Å; R188-Q191 PolarHBondContact O-N 3.1Å; Q191-Y193 VanDerWaalsContact C-N 3.26Å; Q191-Y193 PolarHBondContact O-N 2.82Å; Q191-Y194 WeakPolarHBondContact O-CB 3.45Å; Q191-Y194 PolarHBondContact O-N 2.8Å; Q191-Y194 VanDerWaalsContact O-N 3.12Å; Q191-E195 WeakPolarHBondContact O-CG 3.28Å; Q191-E195 PolarHBondContact O-N 2.97Å; Q191-A464 PolarHBondContact NE2-O 3.43Å
192	Q	87.8	Confident	85.9	Confident	11 Å²	11	26.3 Å²	26.3	5%	0.051	13%	0.125	C	C	.	.	H	α-helix	trans	-61.5	-35.3	175.3	-72.9	-177.2	-20.5	0	0	112.2	R188 M189 E195 Y196 A312	R188-Q192 WeakPolarHBondContact O-CG 3.24Å; R188-Q192 PolarHBondContact O-N 3.35Å; M189-Q192 PolarHBondContact O-N 2.85Å; Q192-E195 PolarHBondContact O-N 2.76Å; Q192-Y196 HydrophobicContact CB-CE2 4.25Å; Q192-Y196 WeakPolarHBondContact O-CD2 3.17Å; Q192-Y196 VanDerWaalsContact O-CG 3.28Å; Q192-Y196 PolarHBondContact O-N 3.27Å; Q192-A312 PolarHBondContact NE2-O 3.37Å
193	Y	90.6	Very high	84.3	Confident	25 Å²	25	28.5 Å²	28.5	10%	0.098	14%	0.135	C	C	.	.	H	α-helix	trans	-65.2	-38.8	174.1	-170.3	-91.4	0	0	0	112.4	R60 V63 I64 M189 A190 Q191 A197 Y218 F222	R60-Y193 HydrophobicContact CB-CD2 4.21Å; R60-Y193 HydrophobicContact CB-CE2 3.75Å; R60-Y193 HydrophobicContact CG-CD2 4.1Å; R60-Y193 HydrophobicContact CG-CE2 3.87Å; R60-Y193 PolarHBondContact NE-OH 2.82Å; R60-Y193 PolarHBondContact NH2-OH 3.37Å; V63-Y193 HydrophobicContact CB-CD2 4.41Å; V63-Y193 HydrophobicContact CG1-CD2 4.29Å; I64-Y193 HydrophobicContact CD1-CE2 3.75Å; I64-Y193 HydrophobicContact CG1-CD2 4.3Å; I64-Y193 HydrophobicContact CG1-CE2 3.89Å; M189-Y193 WeakPolarHBondContact O-CB 3.17Å; M189-Y193 PolarHBondContact O-N 3.15Å; A190-Y193 PolarHBondContact O-N 3.24Å; Q191-Y193 VanDerWaalsContact C-N 3.26Å; Q191-Y193 PolarHBondContact O-N 2.82Å; Y193-A197 VanDerWaalsContact O-CB 3.25Å; Y193-A197 WeakPolarHBondContact O-CB 3.49Å; Y193-A197 PolarHBondContact O-N 3.05Å; Y193-Y218 AromaticContact CD1-CD1 3.6Å; Y193-Y218 HydrophobicContact CD1-CD1 3.6Å; Y193-Y218 AromaticContact CD1-CE1 3.82Å; Y193-Y218 HydrophobicContact CD1-CE1 3.82Å; Y193-Y218 HydrophobicContact CD1-CG 4.02Å; Y193-Y218 AromaticContact CE1-CD1 3.71Å; Y193-Y218 HydrophobicContact CE1-CD1 3.71Å; Y193-Y218 AromaticContact CE1-CE1 3.53Å; Y193-Y218 HydrophobicContact CE1-CE1 3.53Å; Y193-F222 HydrophobicContact CD1-CZ 4.08Å; Y193-F222 AromaticContact CD2-CZ 3.79Å; Y193-F222 HydrophobicContact CD2-CZ 3.79Å; Y193-F222 HydrophobicContact CE2-CZ 4.41Å; Y193-F222 HydrophobicContact CG-CE1 4.49Å; Y193-F222 HydrophobicContact CG-CE2 4.19Å; Y193-F222 AromaticContact CG-CZ 3.59Å; Y193-F222 HydrophobicContact CG-CZ 3.59Å
194	Y	89	Confident	82.9	Confident	7 Å²	7	29.2 Å²	29.2	3%	0.027	14%	0.138	C	C	.	.	H	α-helix	trans	-60.6	-51.4	170.7	176.2	-82.8	0	0	0	110.8	A190 Q191 Y196 A197 N198 E201 H203 V204 L210 A214 C215 Y218	A190-Y194 PolarHBondContact O-N 3.38Å; A190-Y194 VanDerWaalsContact O-N 3.09Å; Q191-Y194 WeakPolarHBondContact O-CB 3.45Å; Q191-Y194 PolarHBondContact O-N 2.8Å; Q191-Y194 VanDerWaalsContact O-N 3.12Å; Y194-Y196 VanDerWaalsContact C-N 3.3Å; Y194-Y196 PolarHBondContact O-N 2.98Å; Y194-A197 PolarHBondContact O-N 2.99Å; Y194-A197 VanDerWaalsContact O-N 3.08Å; Y194-N198 HydrophobicContact CE1-CB 4.37Å; Y194-N198 WeakPolarHBondContact CE2-ND2 3.42Å; Y194-N198 VanDerWaalsContact CZ-ND2 3.28Å; Y194-N198 PolarHBondContact O-N 3.25Å; Y194-N198 PolarHBondContact OH-ND2 2.97Å; Y194-E201 PolarHBondContact OH-OE2 2.92Å; Y194-H203 AromaticContact CE1-NE2 3.04Å; Y194-H203 WeakPolarHBondContact CE1-NE2 3.01Å; Y194-H203 AromaticContact CZ-NE2 3.36Å; Y194-H203 PolarHBondContact OH-NE2 2.89Å; Y194-V204 HydrophobicContact CE1-CG2 4.39Å; Y194-L210 HydrophobicContact CD1-CD2 4.23Å; Y194-A214 HydrophobicContact CD2-CB 4.49Å; Y194-A214 WeakPolarHBondContact CD2-O 3.46Å; Y194-A214 VanDerWaalsContact CE2-C 3.49Å; Y194-A214 HydrophobicContact CE2-CB 3.47Å; Y194-A214 VanDerWaalsContact CE2-CB 3.47Å; Y194-A214 WeakPolarHBondContact CE2-O 3.39Å; Y194-A214 VanDerWaalsContact OH-CB 3.31Å; Y194-A214 WeakPolarHBondContact OH-CB 3.35Å; Y194-C215 HydrophobicContact CD2-CB 4.3Å; Y194-C215 HydrophobicContact CG-CB 4.28Å; Y194-Y218 AromaticContact CD2-CD2 3.84Å; Y194-Y218 HydrophobicContact CD2-CD2 3.84Å; Y194-Y218 AromaticContact CD2-CE2 3.78Å; Y194-Y218 HydrophobicContact CD2-CE2 3.78Å; Y194-Y218 HydrophobicContact CG-CD2 4.37Å; Y194-Y218 HydrophobicContact CG-CE2 4.49Å
195	E	85.1	Confident	81.4	Confident	10 Å²	10	36.4 Å²	36.4	5%	0.047	17%	0.171	C	C	.	.	H	α-helix	trans	-56.4	-41.5	179	-68.1	167.3	-168.7	0	0	111.9	R188 Q191 Q192 N198 Y199 V204 K467	R188-E195 IonicContact NH1-OE1 2.72Å; Q191-E195 WeakPolarHBondContact O-CG 3.28Å; Q191-E195 PolarHBondContact O-N 2.97Å; Q192-E195 PolarHBondContact O-N 2.76Å; E195-N198 CarbonylContact O-C 3.57Å; E195-Y199 WeakPolarHBondContact O-CA 3.28Å; E195-Y199 PolarHBondContact O-N 2.88Å; E195-V204 HydrophobicContact CB-CG1 4.03Å; E195-V204 HydrophobicContact CG-CG1 4.37Å; E195-K467 WeakPolarHBondContact OE1-CE 3.47Å; E195-K467 IonicContact OE1-NZ 3.76Å; E195-K467 PolarHBondContact OE1-NZ 2.91Å
196	Y	86.3	Confident	79.7	Confident	41 Å²	41	41.5 Å²	41.5	16%	0.161	20%	0.195	C	C	.	.	H	α-helix	trans	-80	-20.2	176.8	-61.2	-36.6	0	0	0	114.9	Y56 K59 V63 Q192 Y194	Y56-Y196 AromaticContact CD1-CD1 3.94Å; Y56-Y196 HydrophobicContact CD1-CD1 3.94Å; Y56-Y196 HydrophobicContact CD1-CG 4.42Å; Y56-Y196 AromaticContact CE1-CD1 3.96Å; Y56-Y196 HydrophobicContact CE1-CD1 3.96Å; K59-Y196 HydrophobicContact CB-CD2 3.95Å; K59-Y196 HydrophobicContact CB-CE2 4.07Å; K59-Y196 HydrophobicContact CB-CG 4.21Å; V63-Y196 HydrophobicContact CG2-CD2 3.91Å; V63-Y196 HydrophobicContact CG2-CE2 3.8Å; Q192-Y196 HydrophobicContact CB-CE2 4.25Å; Q192-Y196 WeakPolarHBondContact O-CD2 3.17Å; Q192-Y196 VanDerWaalsContact O-CG 3.28Å; Q192-Y196 PolarHBondContact O-N 3.27Å; Y194-Y196 VanDerWaalsContact C-N 3.3Å; Y194-Y196 PolarHBondContact O-N 2.98Å
197	A	85.7	Confident	78.2	Confident	25 Å²	25	47 Å²	47	21%	0.207	22%	0.221	C	C	.	.	H	α-helix	trans	-76.1	-39.8	172.9	0	0	0	0	0	110.8	Y193 Y194	Y193-A197 VanDerWaalsContact O-CB 3.25Å; Y193-A197 WeakPolarHBondContact O-CB 3.49Å; Y193-A197 PolarHBondContact O-N 3.05Å; Y194-A197 PolarHBondContact O-N 2.99Å; Y194-A197 VanDerWaalsContact O-N 3.08Å
198	N	84.6	Confident	76.7	Confident	45 Å²	45	54.5 Å²	54.5	24%	0.241	25%	0.249	C	C	.	.	S	Bend	trans	-110.1	38.6	-174.5	-70	5.7	0	0	0	112.2	Y194 E195 K200 E201	Y194-N198 HydrophobicContact CE1-CB 4.37Å; Y194-N198 WeakPolarHBondContact CE2-ND2 3.42Å; Y194-N198 VanDerWaalsContact CZ-ND2 3.28Å; Y194-N198 PolarHBondContact O-N 3.25Å; Y194-N198 PolarHBondContact OH-ND2 2.97Å; E195-N198 CarbonylContact O-C 3.57Å; N198-K200 PolarHBondContact O-N 2.91Å; N198-E201 HydrophobicContact CB-CG 3.91Å; N198-E201 WeakPolarHBondContact CB-OE2 3.28Å; N198-E201 PolarHBondContact ND2-OE1 2.7Å; N198-E201 PolarHBondContact ND2-OE2 2.95Å; N198-E201 WeakPolarHBondContact O-CB 3.03Å; N198-E201 PolarHBondContact O-N 2.82Å
199	Y	77.1	Confident	75.3	Confident	37 Å²	37	63.8 Å²	63.8	15%	0.145	29%	0.29	C	S	.	.	T	Hydrogen-bonded Turn	trans	-62.2	-18.6	-174.2	76.9	-88.6	0	0	0	114.6	Y56 E195	Y56-Y199 HydrophobicContact CD1-CD1 4.3Å; Y56-Y199 HydrophobicContact CD1-CG 4.07Å; Y56-Y199 AromaticContact CD2-CD1 3.75Å; Y56-Y199 HydrophobicContact CD2-CD1 3.75Å; Y56-Y199 AromaticContact CD2-CD2 3.61Å; Y56-Y199 HydrophobicContact CD2-CD2 3.61Å; Y56-Y199 AromaticContact CD2-CE1 3.87Å; Y56-Y199 HydrophobicContact CD2-CE1 3.87Å; Y56-Y199 AromaticContact CD2-CE2 3.7Å; Y56-Y199 HydrophobicContact CD2-CE2 3.7Å; Y56-Y199 AromaticContact CD2-CG 3.61Å; Y56-Y199 HydrophobicContact CD2-CG 3.61Å; Y56-Y199 AromaticContact CD2-CZ 3.82Å; Y56-Y199 HydrophobicContact CE1-CD2 4.4Å; Y56-Y199 HydrophobicContact CE1-CG 4.01Å; Y56-Y199 HydrophobicContact CE2-CD1 4.19Å; Y56-Y199 AromaticContact CE2-CD2 3.22Å; Y56-Y199 HydrophobicContact CE2-CD2 3.22Å; Y56-Y199 HydrophobicContact CE2-CE1 4.48Å; Y56-Y199 AromaticContact CE2-CE2 3.56Å; Y56-Y199 HydrophobicContact CE2-CE2 3.56Å; Y56-Y199 AromaticContact CE2-CG 3.55Å; Y56-Y199 HydrophobicContact CE2-CG 3.55Å; Y56-Y199 AromaticContact CG-CD1 3.82Å; Y56-Y199 HydrophobicContact CG-CD1 3.82Å; Y56-Y199 HydrophobicContact CG-CD2 4.35Å; Y56-Y199 HydrophobicContact CG-CE1 4.21Å; Y56-Y199 AromaticContact CG-CG 3.88Å; Y56-Y199 HydrophobicContact CG-CG 3.88Å; Y56-Y199 AromaticContact CZ-CD2 3.67Å; Y56-Y199 AromaticContact CZ-CG 3.75Å; E195-Y199 WeakPolarHBondContact O-CA 3.28Å; E195-Y199 PolarHBondContact O-N 2.88Å
200	K	69.7	Low	74.1	Confident	121 Å²	121	64.6 Å²	64.6	53%	0.526	29%	0.294	S	S	.	.	T	Hydrogen-bonded Turn	trans	-86.9	-0.3	175.5	-61.2	-160.5	176	-158.8	0	114	E49 N198	E49-K200 IonicContact OE2-NZ 2.37Å; E49-K200 PolarHBondContact OE2-NZ 2.92Å; N198-K200 PolarHBondContact O-N 2.91Å
201	E	72.2	Confident	72.8	Confident	65 Å²	65	67.1 Å²	67.1	30%	0.304	31%	0.31	S	S	.	.	S	Bend	trans	-83.2	128.4	176.4	-65.4	-177.5	150.9	0	0	110.6	Y194 N198 H203 V204 Q205	Y194-E201 PolarHBondContact OH-OE2 2.92Å; N198-E201 HydrophobicContact CB-CG 3.91Å; N198-E201 WeakPolarHBondContact CB-OE2 3.28Å; N198-E201 PolarHBondContact ND2-OE1 2.7Å; N198-E201 PolarHBondContact ND2-OE2 2.95Å; N198-E201 WeakPolarHBondContact O-CB 3.03Å; N198-E201 PolarHBondContact O-N 2.82Å; E201-H203 WeakPolarHBondContact CB-CE1 3.28Å; E201-H203 VanDerWaalsContact CG-CE1 3.46Å; E201-H203 WeakPolarHBondContact CG-CE1 3.4Å; E201-H203 PolarHBondContact O-N 3.16Å; E201-H203 VanDerWaalsContact O-N 3.12Å; E201-H203 IonicContact OE1-CE1 3.23Å; E201-H203 PolarHBondContact OE1-CE1 3.47Å; E201-H203 VanDerWaalsContact OE1-CE1 3.23Å; E201-H203 IonicContact OE2-CE1 2.44Å; E201-H203 PolarHBondContact OE2-CE1 3.42Å; E201-H203 IonicContact OE2-NE2 2.76Å; E201-H203 PolarHBondContact OE2-NE2 2.75Å; E201-V204 HydrophobicContact CB-CG2 4.2Å; E201-V204 WeakPolarHBondContact O-CA 3.2Å; E201-V204 WeakPolarHBondContact O-CB 3.45Å; E201-V204 PolarHBondContact O-N 3.35Å; E201-Q205 PolarHBondContact O-N 2.76Å
202	E	57.5	Low	71.6	Confident	155 Å²	155	75 Å²	75	72%	0.724	35%	0.345	S	S	*	.	H	α-helix	trans	-51.1	-39.7	-176.6	-65.7	174.6	164.8	0	0	113.2	V204 Q205 E206	E202-V204 PolarHBondContact O-N 2.99Å; E202-Q205 PolarHBondContact O-N 3.09Å; E202-E206 PolarHBondContact O-N 3.04Å
203	H	60.3	Low	70.7	Confident	48 Å²	48	75.8 Å²	75.8	22%	0.222	36%	0.355	C	S	.	.	H	α-helix	trans	-67.3	-21.8	178.8	64	-103.3	0	0	0	114	Y194 E201 Q207 R208	Y194-H203 AromaticContact CE1-NE2 3.04Å; Y194-H203 WeakPolarHBondContact CE1-NE2 3.01Å; Y194-H203 AromaticContact CZ-NE2 3.36Å; Y194-H203 PolarHBondContact OH-NE2 2.89Å; E201-H203 WeakPolarHBondContact CB-CE1 3.28Å; E201-H203 VanDerWaalsContact CG-CE1 3.46Å; E201-H203 WeakPolarHBondContact CG-CE1 3.4Å; E201-H203 PolarHBondContact O-N 3.16Å; E201-H203 VanDerWaalsContact O-N 3.12Å; E201-H203 IonicContact OE1-CE1 3.23Å; E201-H203 PolarHBondContact OE1-CE1 3.47Å; E201-H203 VanDerWaalsContact OE1-CE1 3.23Å; E201-H203 IonicContact OE2-CE1 2.44Å; E201-H203 PolarHBondContact OE2-CE1 3.42Å; E201-H203 IonicContact OE2-NE2 2.76Å; E201-H203 PolarHBondContact OE2-NE2 2.75Å; H203-Q207 CarbonylContact O-C 3.54Å; H203-Q207 PolarHBondContact O-N 2.94Å; H203-R208 HydrophobicContact CB-CB 4.3Å; H203-R208 PolarHBondContact O-N 3.44Å
204	V	62.9	Low	69.7	Low	23 Å²	23	76.3 Å²	76.3	14%	0.139	36%	0.364	C	S	.	.	H	α-helix	trans	-80.3	-41	172.9	-179	0	0	0	0	109.9	Y194 E195 E201 E202 Q207	Y194-V204 HydrophobicContact CE1-CG2 4.39Å; E195-V204 HydrophobicContact CB-CG1 4.03Å; E195-V204 HydrophobicContact CG-CG1 4.37Å; E201-V204 HydrophobicContact CB-CG2 4.2Å; E201-V204 WeakPolarHBondContact O-CA 3.2Å; E201-V204 WeakPolarHBondContact O-CB 3.45Å; E201-V204 PolarHBondContact O-N 3.35Å; E202-V204 PolarHBondContact O-N 2.99Å; V204-Q207 PolarHBondContact O-N 3.26Å
205	Q	59.4	Low	69.3	Low	150 Å²	150	76.1 Å²	76.1	70%	0.701	36%	0.364	S	S	*	.	H	α-helix	trans	-68.7	-44.5	-178.2	-163.9	162.4	0.7	0	0	111.8	E201 E202 Q207	E201-Q205 PolarHBondContact O-N 2.76Å; E202-Q205 PolarHBondContact O-N 3.09Å; Q205-Q207 VanDerWaalsContact C-N 3.27Å; Q205-Q207 PolarHBondContact O-N 2.94Å
206	E	58.3	Low	69.4	Low	108 Å²	108	79.2 Å²	79.2	51%	0.505	38%	0.376	S	S	.	.	T	Hydrogen-bonded Turn	trans	-81.4	2.6	174.1	-64.1	-168.3	-161.5	0	0	114.3	E202 R208	E202-E206 PolarHBondContact O-N 3.04Å; E206-R208 HydrophobicContact CB-CG 4.03Å; E206-R208 PolarHBondContact O-N 3.48Å; E206-R208 IonicContact OE1-NH2 3.61Å; E206-R208 IonicContact OE2-CZ 2.98Å; E206-R208 IonicContact OE2-NE 2.64Å; E206-R208 PolarHBondContact OE2-NE 3.33Å; E206-R208 IonicContact OE2-NH2 2.66Å; E206-R208 PolarHBondContact OE2-NH2 3.46Å
207	Q	61.7	Low	69.5	Low	115 Å²	115	80.3 Å²	80.3	54%	0.537	39%	0.39	S	S	.	.	T	Hydrogen-bonded Turn	trans	52.4	24.1	-175.3	-53.1	-172.7	36.7	0	0	115.1	H203 V204 Q205	H203-Q207 CarbonylContact O-C 3.54Å; H203-Q207 PolarHBondContact O-N 2.94Å; V204-Q207 PolarHBondContact O-N 3.26Å; Q205-Q207 VanDerWaalsContact C-N 3.27Å; Q205-Q207 PolarHBondContact O-N 2.94Å
208	R	61.3	Low	69.8	Low	159 Å²	159	82.6 Å²	82.6	60%	0.6	39%	0.394	S	S	*	.	P	Polyproline II helix	trans	-62.2	161.9	176.1	-70.6	-169	-172.8	-178.8	12.6	111	H203 E206 L210	H203-R208 HydrophobicContact CB-CB 4.3Å; H203-R208 PolarHBondContact O-N 3.44Å; E206-R208 HydrophobicContact CB-CG 4.03Å; E206-R208 PolarHBondContact O-N 3.48Å; E206-R208 IonicContact OE1-NH2 3.61Å; E206-R208 IonicContact OE2-CZ 2.98Å; E206-R208 IonicContact OE2-NE 2.64Å; E206-R208 PolarHBondContact OE2-NE 3.33Å; E206-R208 IonicContact OE2-NH2 2.66Å; E206-R208 PolarHBondContact OE2-NH2 3.46Å; R208-L210 PolarHBondContact O-N 3Å
209	K	61.7	Low	70.1	Confident	195 Å²	195	80.5 Å²	80.5	85%	0.848	38%	0.382	S	S	*	.	P	Polyproline II helix	trans	-53.8	129.6	175.8	-71.4	-179.4	179.2	173.5	0	110.2
210	L	66	Low	70.8	Confident	16 Å²	16	79.1 Å²	79.1	8%	0.084	38%	0.378	C	S	.	.	P	Polyproline II helix	trans	-56.5	140.1	-177.4	-87.5	69	0	0	0	111.1	Y194 R208 C215	Y194-L210 HydrophobicContact CD1-CD2 4.23Å; R208-L210 PolarHBondContact O-N 3Å; L210-C215 HydrophobicContact CD2-CB 4.22Å
211	P	63.1	Low	71.9	Confident	53 Å²	53	75.4 Å²	75.4	34%	0.344	37%	0.365	S	S	.	.	P	Polyproline II helix	trans	-61.8	140.3	173.2	25.7	-33.6	0	0	0	110.8	G213 A214	P211-G213 PolarHBondContact O-N 3.44Å; P211-G213 VanDerWaalsContact O-N 3.14Å; P211-A214 HydrophobicContact CG-CB 3.99Å; P211-A214 PolarHBondContact O-N 3.25Å
212	K	64.3	Low	72.9	Confident	167 Å²	167	73 Å²	73	73%	0.726	35%	0.354	S	S	*	.	T	Hydrogen-bonded Turn	trans	-60.1	118.9	-171.2	-58.7	-166.3	170.8	-81.7	0	111.3	E465	K212-E465 WeakPolarHBondContact CG-OE1 3.37Å; K212-E465 VanDerWaalsContact NZ-CD 3.3Å; K212-E465 IonicContact NZ-OE1 3.08Å; K212-E465 PolarHBondContact NZ-OE1 2.96Å; K212-E465 VanDerWaalsContact NZ-OE1 3.08Å; K212-E465 IonicContact NZ-OE2 2.67Å; K212-E465 PolarHBondContact NZ-OE2 3.47Å
213	G	67.8	Low	74.6	Confident	26 Å²	26	65.7 Å²	65.7	27%	0.268	32%	0.32	S	S	.	.	T	Hydrogen-bonded Turn	trans	91.3	-8.6	172.5	0	0	0	0	0	116.9	P211 C215 Y216	P211-G213 PolarHBondContact O-N 3.44Å; P211-G213 VanDerWaalsContact O-N 3.14Å; G213-C215 VanDerWaalsContact C-N 3.34Å; G213-C215 PolarHBondContact O-N 3.06Å; G213-Y216 VanDerWaalsContact CA-CE2 3.49Å; G213-Y216 VanDerWaalsContact O-CB 3.3Å; G213-Y216 WeakPolarHBondContact O-CB 3.42Å; G213-Y216 VanDerWaalsContact O-CG 3.24Å; G213-Y216 PolarHBondContact O-N 3.47Å
214	A	70.5	Confident	76.2	Confident	36 Å²	36	63.4 Å²	63.4	30%	0.298	31%	0.309	S	S	.	.	T	Hydrogen-bonded Turn	trans	-66.2	-33.6	-173.9	0	0	0	0	0	113.6	Y194 P211 Y216	Y194-A214 HydrophobicContact CD2-CB 4.49Å; Y194-A214 WeakPolarHBondContact CD2-O 3.46Å; Y194-A214 VanDerWaalsContact CE2-C 3.49Å; Y194-A214 HydrophobicContact CE2-CB 3.47Å; Y194-A214 VanDerWaalsContact CE2-CB 3.47Å; Y194-A214 WeakPolarHBondContact CE2-O 3.39Å; Y194-A214 VanDerWaalsContact OH-CB 3.31Å; Y194-A214 WeakPolarHBondContact OH-CB 3.35Å; P211-A214 HydrophobicContact CG-CB 3.99Å; P211-A214 PolarHBondContact O-N 3.25Å; A214-Y216 VanDerWaalsContact C-N 3.32Å; A214-Y216 PolarHBondContact O-N 2.95Å
215	C	81	Confident	77.7	Confident	4 Å²	4	65.8 Å²	65.8	3%	0.027	32%	0.32	C	S	.	.	T	Hydrogen-bonded Turn	trans	-78.9	-10.4	179	-166.6	0	0	0	0	114.2	Y194 L210 G213 S217 Y218 I219	Y194-C215 HydrophobicContact CD2-CB 4.3Å; Y194-C215 HydrophobicContact CG-CB 4.28Å; L210-C215 HydrophobicContact CD2-CB 4.22Å; G213-C215 VanDerWaalsContact C-N 3.34Å; G213-C215 PolarHBondContact O-N 3.06Å; C215-S217 PolarHBondContact O-N 3.46Å; C215-Y218 PolarHBondContact O-N 2.87Å; C215-Y218 VanDerWaalsContact O-N 3.14Å; C215-I219 HydrophobicContact CB-CD1 4.24Å; C215-I219 PolarHBondContact O-N 2.91Å
216	Y	86.3	Confident	79.5	Confident	74 Å²	74	58.9 Å²	58.9	29%	0.29	29%	0.288	S	S	.	.	H	α-helix	trans	-58.2	-42.7	-166.8	-71.4	-3.9	0	0	0	113.7	G213 A214 Y218 I219 I220 L461 A464	G213-Y216 VanDerWaalsContact CA-CE2 3.49Å; G213-Y216 VanDerWaalsContact O-CB 3.3Å; G213-Y216 WeakPolarHBondContact O-CB 3.42Å; G213-Y216 VanDerWaalsContact O-CG 3.24Å; G213-Y216 PolarHBondContact O-N 3.47Å; A214-Y216 VanDerWaalsContact C-N 3.32Å; A214-Y216 PolarHBondContact O-N 2.95Å; Y216-Y218 VanDerWaalsContact C-N 3.32Å; Y216-Y218 PolarHBondContact O-N 3.44Å; Y216-I219 PolarHBondContact O-N 3.34Å; Y216-I220 WeakPolarHBondContact O-CD1 3.28Å; Y216-I220 VanDerWaalsContact O-CG1 3.28Å; Y216-I220 WeakPolarHBondContact O-CG1 3.48Å; Y216-I220 PolarHBondContact O-N 3.21Å; Y216-L461 VanDerWaalsContact CB-CD2 3.43Å; Y216-L461 HydrophobicContact CD1-CB 4.44Å; Y216-L461 HydrophobicContact CD1-CD2 3.32Å; Y216-L461 HydrophobicContact CD1-CG 4.47Å; Y216-L461 HydrophobicContact CD2-CD2 4.07Å; Y216-L461 HydrophobicContact CE1-CB 4.28Å; Y216-L461 HydrophobicContact CE1-CD2 4Å; Y216-L461 VanDerWaalsContact CE1-O 3.28Å; Y216-L461 WeakPolarHBondContact CE1-O 3.26Å; Y216-L461 HydrophobicContact CG-CD2 3.35Å; Y216-L461 PolarHBondContact OH-O 2.97Å; Y216-A464 HydrophobicContact CD1-CB 4.4Å; Y216-A464 HydrophobicContact CE1-CB 4.02Å
217	S	88.7	Confident	81.2	Confident	65 Å²	65	54 Å²	54	46%	0.455	27%	0.265	S	S	.	.	H	α-helix	trans	-61.9	-36.7	-179.5	-55.8	0	0	0	0	113.3	C215 T221	C215-S217 PolarHBondContact O-N 3.46Å; S217-T221 WeakPolarHBondContact O-CB 3.46Å; S217-T221 PolarHBondContact O-N 3.07Å; S217-T221 VanDerWaalsContact O-N 3.14Å; S217-T221 PolarHBondContact O-OG1 3.05Å
218	Y	91	Very high	82.8	Confident	72 Å²	72	49.9 Å²	49.9	28%	0.282	25%	0.247	S	C	.	.	H	α-helix	trans	-76.3	-40	179	-60.6	-60.4	0	0	0	111.8	Y193 Y194 C215 Y216 T221 F222	Y193-Y218 AromaticContact CD1-CD1 3.6Å; Y193-Y218 HydrophobicContact CD1-CD1 3.6Å; Y193-Y218 AromaticContact CD1-CE1 3.82Å; Y193-Y218 HydrophobicContact CD1-CE1 3.82Å; Y193-Y218 HydrophobicContact CD1-CG 4.02Å; Y193-Y218 AromaticContact CE1-CD1 3.71Å; Y193-Y218 HydrophobicContact CE1-CD1 3.71Å; Y193-Y218 AromaticContact CE1-CE1 3.53Å; Y193-Y218 HydrophobicContact CE1-CE1 3.53Å; Y194-Y218 AromaticContact CD2-CD2 3.84Å; Y194-Y218 HydrophobicContact CD2-CD2 3.84Å; Y194-Y218 AromaticContact CD2-CE2 3.78Å; Y194-Y218 HydrophobicContact CD2-CE2 3.78Å; Y194-Y218 HydrophobicContact CG-CD2 4.37Å; Y194-Y218 HydrophobicContact CG-CE2 4.49Å; C215-Y218 PolarHBondContact O-N 2.87Å; C215-Y218 VanDerWaalsContact O-N 3.14Å; Y216-Y218 VanDerWaalsContact C-N 3.32Å; Y216-Y218 PolarHBondContact O-N 3.44Å; Y218-T221 PolarHBondContact O-N 3.43Å; Y218-F222 WeakPolarHBondContact O-CB 3.09Å; Y218-F222 PolarHBondContact O-N 3.04Å
219	I	91.1	Very high	84.5	Confident	1 Å²	1	43.4 Å²	43.4	1%	0.005	22%	0.224	C	C	.	.	H	α-helix	trans	-59.8	-48.2	175	-65.9	170.7	0	0	0	110.5	T187 A190 C215 Y216 T221 Q223 L461 A464	T187-I219 HydrophobicContact CG2-CD1 4.29Å; T187-I219 HydrophobicContact CG2-CG1 4.35Å; T187-I219 HydrophobicContact CG2-CG2 4.33Å; A190-I219 HydrophobicContact CB-CB 4.46Å; A190-I219 HydrophobicContact CB-CG1 3.88Å; C215-I219 HydrophobicContact CB-CD1 4.24Å; C215-I219 PolarHBondContact O-N 2.91Å; Y216-I219 PolarHBondContact O-N 3.34Å; I219-T221 PolarHBondContact O-N 3.04Å; I219-Q223 HydrophobicContact CG2-CG 4.33Å; I219-Q223 VanDerWaalsContact O-CB 3.3Å; I219-Q223 WeakPolarHBondContact O-CB 3.33Å; I219-Q223 VanDerWaalsContact O-CG 3.24Å; I219-Q223 WeakPolarHBondContact O-CG 3.29Å; I219-Q223 PolarHBondContact O-N 3.39Å; I219-L461 HydrophobicContact CB-CD2 4.5Å; I219-A464 HydrophobicContact CD1-CB 3.72Å
220	I	92.1	Very high	86.1	Confident	9 Å²	9	34.3 Å²	34.3	5%	0.046	19%	0.185	C	C	.	.	H	α-helix	trans	-55.8	-54.3	175.5	-66.8	159.4	0	0	0	109.7	Y216 F222 Q223 S224 L398 L399 T457 L461	Y216-I220 WeakPolarHBondContact O-CD1 3.28Å; Y216-I220 VanDerWaalsContact O-CG1 3.28Å; Y216-I220 WeakPolarHBondContact O-CG1 3.48Å; Y216-I220 PolarHBondContact O-N 3.21Å; I220-F222 PolarHBondContact O-N 3.3Å; I220-Q223 PolarHBondContact O-N 2.92Å; I220-S224 WeakPolarHBondContact O-CB 3.28Å; I220-S224 PolarHBondContact O-N 2.94Å; I220-S224 PolarHBondContact O-OG 3.47Å; I220-L398 HydrophobicContact CD1-CB 4.08Å; I220-L398 HydrophobicContact CG1-CB 4.38Å; I220-L398 HydrophobicContact CG2-CB 4.17Å; I220-L399 HydrophobicContact CB-CD2 3.99Å; I220-L399 HydrophobicContact CD1-CD2 3.89Å; I220-L399 HydrophobicContact CG2-CD2 3.96Å; I220-L399 HydrophobicContact CG2-CG 4.01Å; I220-T457 HydrophobicContact CB-CG2 4.28Å; I220-T457 HydrophobicContact CG1-CG2 3.55Å; I220-L461 HydrophobicContact CD1-CD2 4.46Å; I220-L461 HydrophobicContact CG1-CD1 4.36Å; I220-L461 HydrophobicContact CG1-CD2 4.32Å
221	T	93.1	Very high	87.5	Confident	43 Å²	43	33.9 Å²	33.9	26%	0.264	18%	0.183	S	C	.	.	H	α-helix	trans	-59.7	-45.5	-175.5	-55.6	0	0	0	0	112.8	S217 Y218 I219 S224 I225 L396	S217-T221 WeakPolarHBondContact O-CB 3.46Å; S217-T221 PolarHBondContact O-N 3.07Å; S217-T221 VanDerWaalsContact O-N 3.14Å; S217-T221 PolarHBondContact O-OG1 3.05Å; Y218-T221 PolarHBondContact O-N 3.43Å; I219-T221 PolarHBondContact O-N 3.04Å; T221-S224 PolarHBondContact O-N 3.31Å; T221-I225 HydrophobicContact CG2-CD1 3.93Å; T221-I225 VanDerWaalsContact O-CG1 3.3Å; T221-I225 WeakPolarHBondContact O-CG1 3.49Å; T221-I225 PolarHBondContact O-N 3.07Å; T221-L396 HydrophobicContact CG2-CD2 4.5Å
222	F	93.9	Very high	89.1	Confident	14 Å²	14	33.6 Å²	33.6	6%	0.061	18%	0.178	C	C	.	.	H	α-helix	trans	-72	-38.5	-177.4	-77.5	18.5	0	0	0	112	V63 I64 V67 I186 A190 Y193 Y218 I220 I225 F226	V63-F222 HydrophobicContact CG1-CE2 3.97Å; I64-F222 HydrophobicContact CG1-CZ 4.45Å; V67-F222 HydrophobicContact CG1-CD2 4.4Å; V67-F222 HydrophobicContact CG1-CG 4.48Å; V67-F222 HydrophobicContact CG2-CD2 3.79Å; V67-F222 HydrophobicContact CG2-CE2 3.95Å; I186-F222 HydrophobicContact CG2-CB 4.31Å; A190-F222 VanDerWaalsContact CA-CD2 3.5Å; A190-F222 HydrophobicContact CB-CB 4.13Å; A190-F222 HydrophobicContact CB-CD2 3.62Å; A190-F222 HydrophobicContact CB-CE2 4.3Å; A190-F222 HydrophobicContact CB-CG 4.07Å; Y193-F222 HydrophobicContact CD1-CZ 4.08Å; Y193-F222 AromaticContact CD2-CZ 3.79Å; Y193-F222 HydrophobicContact CD2-CZ 3.79Å; Y193-F222 HydrophobicContact CE2-CZ 4.41Å; Y193-F222 HydrophobicContact CG-CE1 4.49Å; Y193-F222 HydrophobicContact CG-CE2 4.19Å; Y193-F222 AromaticContact CG-CZ 3.59Å; Y193-F222 HydrophobicContact CG-CZ 3.59Å; Y218-F222 WeakPolarHBondContact O-CB 3.09Å; Y218-F222 PolarHBondContact O-N 3.04Å; I220-F222 PolarHBondContact O-N 3.3Å; F222-I225 PolarHBondContact O-N 3.45Å; F222-F226 WeakPolarHBondContact O-CB 3.48Å; F222-F226 PolarHBondContact O-N 3.48Å
223	Q	93.5	Very high	90.6	Very high	2 Å²	2	25.7 Å²	25.7	1%	0.009	14%	0.144	C	C	.	.	H	α-helix	trans	-63.4	-45.1	173.2	-72.1	-74.1	-14.4	0	0	110.9	I186 T187 I219 I220 I225 F226 F227 S456 Y474	I186-Q223 HydrophobicContact CG2-CG 4.44Å; T187-Q223 PolarHBondContact OG1-NE2 2.97Å; I219-Q223 HydrophobicContact CG2-CG 4.33Å; I219-Q223 VanDerWaalsContact O-CB 3.3Å; I219-Q223 WeakPolarHBondContact O-CB 3.33Å; I219-Q223 VanDerWaalsContact O-CG 3.24Å; I219-Q223 WeakPolarHBondContact O-CG 3.29Å; I219-Q223 PolarHBondContact O-N 3.39Å; I220-Q223 PolarHBondContact O-N 2.92Å; Q223-I225 PolarHBondContact O-N 2.89Å; Q223-F226 PolarHBondContact O-N 3.32Å; Q223-F227 VanDerWaalsContact O-CD2 3.3Å; Q223-F227 WeakPolarHBondContact O-CD2 3.08Å; Q223-F227 PolarHBondContact O-N 3.09Å; Q223-S456 PolarHBondContact OE1-OG 3.15Å; Q223-Y474 PolarHBondContact NE2-OH 3.48Å
224	S	93.6	Very high	91.9	Very high	0 Å²	0	24.7 Å²	24.7	0%	0	13%	0.132	C	C	.	.	H	α-helix	trans	-57	-49.8	175.2	-58	0	0	0	0	111.9	I220 T221 F226 F227 V228 S395 L396	I220-S224 WeakPolarHBondContact O-CB 3.28Å; I220-S224 PolarHBondContact O-N 2.94Å; I220-S224 PolarHBondContact O-OG 3.47Å; T221-S224 PolarHBondContact O-N 3.31Å; S224-F226 PolarHBondContact O-N 3.39Å; S224-F227 PolarHBondContact O-N 3.39Å; S224-V228 VanDerWaalsContact O-CG2 3.23Å; S224-V228 WeakPolarHBondContact O-CG2 3.39Å; S224-V228 PolarHBondContact O-N 3.16Å; S224-S395 WeakPolarHBondContact CB-OG 3.21Å; S224-S395 PolarHBondContact OG-OG 3.42Å; S224-L396 WeakPolarHBondContact OG-CD2 3.36Å
225	I	94.2	Very high	93.1	Very high	73 Å²	73	23.7 Å²	23.7	37%	0.374	12%	0.122	S	C	.	.	H	α-helix	trans	-60.9	-44.3	179	-68.5	166.3	0	0	0	111.4	T221 F222 Q223 F227 V228 I229	T221-I225 HydrophobicContact CG2-CD1 3.93Å; T221-I225 VanDerWaalsContact O-CG1 3.3Å; T221-I225 WeakPolarHBondContact O-CG1 3.49Å; T221-I225 PolarHBondContact O-N 3.07Å; F222-I225 PolarHBondContact O-N 3.45Å; Q223-I225 PolarHBondContact O-N 2.89Å; I225-F227 PolarHBondContact O-N 3.42Å; I225-V228 PolarHBondContact O-N 2.98Å; I225-I229 HydrophobicContact CG2-CD1 4.13Å; I225-I229 PolarHBondContact O-N 3.45Å
226	F	95.9	Very high	93.8	Very high	5 Å²	5	27.4 Å²	27.4	2%	0.022	14%	0.138	C	C	.	.	H	α-helix	trans	-57	-49.2	176.4	167	-96.8	0	0	0	111.4	S71 A74 W179 L182 I186 F222 Q223 S224 I229 F230	S71-F226 WeakPolarHBondContact OG-CD2 3.49Å; A74-F226 HydrophobicContact CB-CE2 4.15Å; W179-F226 HydrophobicContact CZ3-CE1 4.47Å; W179-F226 HydrophobicContact CZ3-CZ 4.15Å; L182-F226 HydrophobicContact CD1-CE2 4.07Å; L182-F226 HydrophobicContact CD2-CE2 3.73Å; L182-F226 HydrophobicContact CD2-CZ 3.52Å; L182-F226 HydrophobicContact CG-CE2 3.89Å; L182-F226 HydrophobicContact CG-CZ 3.95Å; I186-F226 HydrophobicContact CD1-CB 4.27Å; I186-F226 HydrophobicContact CD1-CD2 3.79Å; I186-F226 HydrophobicContact CD1-CG 4.21Å; I186-F226 HydrophobicContact CG1-CB 4.4Å; I186-F226 HydrophobicContact CG1-CD2 3.89Å; I186-F226 HydrophobicContact CG1-CE2 4.47Å; I186-F226 HydrophobicContact CG1-CG 4.07Å; I186-F226 HydrophobicContact CG2-CB 4.18Å; F222-F226 WeakPolarHBondContact O-CB 3.48Å; F222-F226 PolarHBondContact O-N 3.48Å; Q223-F226 PolarHBondContact O-N 3.32Å; S224-F226 PolarHBondContact O-N 3.39Å; F226-I229 PolarHBondContact O-N 3.29Å; F226-F230 HydrophobicContact CE1-CB 4.27Å; F226-F230 HydrophobicContact CE2-CB 4.4Å; F226-F230 HydrophobicContact CZ-CB 4.06Å; F226-F230 HydrophobicContact CZ-CG 4.31Å; F226-F230 VanDerWaalsContact O-CB 3.28Å; F226-F230 WeakPolarHBondContact O-CB 3.44Å; F226-F230 PolarHBondContact O-N 2.89Å
227	F	95.1	Very high	94.2	Very high	6 Å²	6	24 Å²	24	3%	0.026	13%	0.125	C	C	.	.	H	α-helix	trans	-70	-32.5	-179.3	-81.6	-74.5	0	0	0	113.6	Q223 S224 I225 I229 F230 N231 K452 T453	Q223-F227 VanDerWaalsContact O-CD2 3.3Å; Q223-F227 WeakPolarHBondContact O-CD2 3.08Å; Q223-F227 PolarHBondContact O-N 3.09Å; S224-F227 PolarHBondContact O-N 3.39Å; I225-F227 PolarHBondContact O-N 3.42Å; F227-I229 VanDerWaalsContact C-N 3.35Å; F227-I229 PolarHBondContact O-N 2.92Å; F227-F230 HydrophobicContact CD1-CD1 4.22Å; F227-F230 PolarHBondContact O-N 3.45Å; F227-N231 VanDerWaalsContact O-CB 3.22Å; F227-N231 WeakPolarHBondContact O-CB 3.43Å; F227-N231 PolarHBondContact O-N 3.31Å; F227-N231 PolarHBondContact O-ND2 3.05Å; F227-N231 VanDerWaalsContact O-ND2 3.12Å; F227-K452 HydrophobicContact CD1-CG 4.38Å; F227-K452 HydrophobicContact CE1-CG 3.72Å; F227-K452 HydrophobicContact CZ-CG 4.28Å; F227-T453 HydrophobicContact CB-CG2 4.15Å; F227-T453 WeakPolarHBondContact CB-OG1 3.47Å; F227-T453 HydrophobicContact CD2-CG2 3.77Å; F227-T453 HydrophobicContact CG-CG2 4.19Å; F227-T453 WeakPolarHBondContact CG-OG1 3.49Å
228	V	95.9	Very high	94.5	Very high	27 Å²	27	20.9 Å²	20.9	16%	0.164	10%	0.104	C	C	.	.	H	α-helix	trans	-57.3	-48.8	172.3	170.3	0	0	0	0	110.7	S224 I225 S389 L393	S224-V228 VanDerWaalsContact O-CG2 3.23Å; S224-V228 WeakPolarHBondContact O-CG2 3.39Å; S224-V228 PolarHBondContact O-N 3.16Å; I225-V228 PolarHBondContact O-N 2.98Å; V228-S389 WeakPolarHBondContact CG2-O 3.49Å; V228-S389 WeakPolarHBondContact O-CB 3.47Å; V228-S389 PolarHBondContact O-OG 2.9Å; V228-L393 HydrophobicContact CG2-CD2 3.68Å; V228-L393 HydrophobicContact CG2-CG 3.76Å
229	I	96.4	Very high	94.6	Very high	23 Å²	23	21.9 Å²	21.9	12%	0.118	11%	0.109	C	C	.	.	H	α-helix	trans	-71.5	-47	179.6	-62.9	169.3	0	0	0	110.4	F72 M75 I225 F226 F227 N231 L232	F72-I229 HydrophobicContact CD1-CG2 3.98Å; F72-I229 HydrophobicContact CE1-CG2 4.12Å; F72-I229 HydrophobicContact CE2-CD1 4.21Å; F72-I229 HydrophobicContact CG-CG2 4.23Å; F72-I229 HydrophobicContact CZ-CD1 4.46Å; F72-I229 HydrophobicContact CZ-CG2 4.5Å; M75-I229 HydrophobicContact CB-CG2 4.21Å; M75-I229 WeakPolarHBondContact CG-O 3.24Å; M75-I229 HydrophobicContact SD-CG2 4.01Å; I225-I229 HydrophobicContact CG2-CD1 4.13Å; I225-I229 PolarHBondContact O-N 3.45Å; F226-I229 PolarHBondContact O-N 3.29Å; F227-I229 VanDerWaalsContact C-N 3.35Å; F227-I229 PolarHBondContact O-N 2.92Å; I229-N231 VanDerWaalsContact C-N 3.34Å; I229-N231 PolarHBondContact O-N 2.89Å; I229-L232 WeakPolarHBondContact O-CB 3.44Å; I229-L232 PolarHBondContact O-N 2.78Å
230	F	95.6	Very high	94.7	Very high	4 Å²	4	22.4 Å²	22.4	2%	0.018	11%	0.113	C	C	.	.	H	α-helix	trans	-59.1	-42	-179.4	169.6	-100.8	0	0	0	112.5	Y78 W179 F226 F227 L232 S233 F234	Y78-F230 AromaticContact CD1-CE2 3.7Å; Y78-F230 HydrophobicContact CD1-CE2 3.7Å; Y78-F230 AromaticContact CD1-CZ 3.6Å; Y78-F230 HydrophobicContact CD1-CZ 3.6Å; Y78-F230 HydrophobicContact CD2-CE2 4.43Å; Y78-F230 HydrophobicContact CE1-CE2 4.47Å; Y78-F230 AromaticContact CE1-CZ 3.95Å; Y78-F230 HydrophobicContact CE1-CZ 3.95Å; Y78-F230 AromaticContact CG-CE2 3.68Å; Y78-F230 HydrophobicContact CG-CE2 3.68Å; Y78-F230 AromaticContact CG-CZ 3.98Å; Y78-F230 HydrophobicContact CG-CZ 3.98Å; W179-F230 HydrophobicContact CH2-CD1 4.27Å; W179-F230 AromaticContact CH2-CD2 3.86Å; W179-F230 HydrophobicContact CH2-CD2 3.86Å; W179-F230 AromaticContact CH2-CE1 3.86Å; W179-F230 HydrophobicContact CH2-CE1 3.86Å; W179-F230 AromaticContact CH2-CE2 3.42Å; W179-F230 HydrophobicContact CH2-CE2 3.42Å; W179-F230 VanDerWaalsContact CH2-CE2 3.42Å; W179-F230 HydrophobicContact CH2-CG 4.28Å; W179-F230 AromaticContact CH2-CZ 3.43Å; W179-F230 HydrophobicContact CH2-CZ 3.43Å; W179-F230 VanDerWaalsContact CH2-CZ 3.43Å; W179-F230 AromaticContact CZ2-CE2 3.8Å; W179-F230 HydrophobicContact CZ2-CE2 3.8Å; W179-F230 AromaticContact CZ2-CZ 3.76Å; W179-F230 HydrophobicContact CZ2-CZ 3.76Å; F226-F230 HydrophobicContact CE1-CB 4.27Å; F226-F230 HydrophobicContact CE2-CB 4.4Å; F226-F230 HydrophobicContact CZ-CB 4.06Å; F226-F230 HydrophobicContact CZ-CG 4.31Å; F226-F230 VanDerWaalsContact O-CB 3.28Å; F226-F230 WeakPolarHBondContact O-CB 3.44Å; F226-F230 PolarHBondContact O-N 2.89Å; F227-F230 HydrophobicContact CD1-CD1 4.22Å; F227-F230 PolarHBondContact O-N 3.45Å; F230-L232 PolarHBondContact O-N 2.91Å; F230-S233 WeakPolarHBondContact O-CB 3.49Å; F230-S233 PolarHBondContact O-N 3.5Å; F230-S233 PolarHBondContact O-OG 3.33Å; F230-F234 HydrophobicContact CE1-CE2 4.21Å
231	N	95.3	Very high	94.6	Very high	7 Å²	7	22.1 Å²	22.1	4%	0.037	11%	0.112	C	C	.	.	H	α-helix	trans	-66.5	-18.4	-178.2	-73.5	-28.1	0	0	0	113.4	F227 I229 S233 F234 C388 S392	F227-N231 VanDerWaalsContact O-CB 3.22Å; F227-N231 WeakPolarHBondContact O-CB 3.43Å; F227-N231 PolarHBondContact O-N 3.31Å; F227-N231 PolarHBondContact O-ND2 3.05Å; F227-N231 VanDerWaalsContact O-ND2 3.12Å; I229-N231 VanDerWaalsContact C-N 3.34Å; I229-N231 PolarHBondContact O-N 2.89Å; N231-S233 PolarHBondContact O-N 2.93Å; N231-F234 WeakPolarHBondContact O-CD2 3.22Å; N231-F234 PolarHBondContact O-N 2.94Å; N231-C388 HydrophobicContact CB-CB 3.77Å; N231-C388 PolarHBondContact ND2-O 3.04Å; N231-S392 PolarHBondContact ND2-OG 3.07Å
232	L	95.7	Very high	94.6	Very high	47 Å²	47	24.6 Å²	24.6	25%	0.246	12%	0.116	C	C	.	.	T	Hydrogen-bonded Turn	trans	-68.1	-15.9	169.2	-63	172.4	0	0	0	112.7	M75 I229 F230 F234 V235 F236 L386 S389	M75-L232 HydrophobicContact CG-CB 4.48Å; M75-L232 HydrophobicContact SD-CB 3.92Å; I229-L232 WeakPolarHBondContact O-CB 3.44Å; I229-L232 PolarHBondContact O-N 2.78Å; F230-L232 PolarHBondContact O-N 2.91Å; L232-F234 PolarHBondContact O-N 2.99Å; L232-V235 HydrophobicContact CD2-CG2 4.44Å; L232-V235 WeakPolarHBondContact O-CA 3.49Å; L232-V235 WeakPolarHBondContact O-CB 3.48Å; L232-V235 PolarHBondContact O-N 3.17Å; L232-F236 HydrophobicContact CB-CD2 4.31Å; L232-F236 HydrophobicContact CB-CE2 4.05Å; L232-F236 WeakPolarHBondContact O-CD2 3.49Å; L232-F236 PolarHBondContact O-N 3.22Å; L232-F236 VanDerWaalsContact O-N 3.13Å; L232-L386 HydrophobicContact CD2-CD2 4.29Å; L232-S389 WeakPolarHBondContact CD2-OG 3.28Å
233	S	96	Very high	94.5	Very high	1 Å²	1	30.3 Å²	30.3	1%	0.007	15%	0.147	C	C	.	.	H	α-helix	trans	-57.5	-35.1	174.4	63	0	0	0	0	112.7	M75 S79 F230 N231 V235 F236 A237	M75-S233 WeakPolarHBondContact O-CB 3.17Å; S79-S233 VanDerWaalsContact CB-O 3.28Å; S79-S233 WeakPolarHBondContact CB-O 3.36Å; F230-S233 WeakPolarHBondContact O-CB 3.49Å; F230-S233 PolarHBondContact O-N 3.5Å; F230-S233 PolarHBondContact O-OG 3.33Å; N231-S233 PolarHBondContact O-N 2.93Å; S233-V235 VanDerWaalsContact C-N 3.27Å; S233-V235 PolarHBondContact O-N 3.32Å; S233-F236 PolarHBondContact O-N 2.88Å; S233-A237 VanDerWaalsContact O-CB 3.26Å; S233-A237 WeakPolarHBondContact O-CB 3.44Å; S233-A237 PolarHBondContact O-N 3.29Å
234	F	95	Very high	94.3	Very high	5 Å²	5	31 Å²	31	2%	0.022	15%	0.151	C	C	.	.	H	α-helix	trans	-66.2	-26.9	174.2	-63.8	-67.9	0	0	0	113	Y78 F230 N231 L232 M356 I360 I381 Y384	Y78-F234 AromaticContact CE1-CE1 3.79Å; Y78-F234 HydrophobicContact CE1-CE1 3.79Å; Y78-F234 AromaticContact CE1-CZ 3.93Å; Y78-F234 HydrophobicContact CE1-CZ 3.93Å; F230-F234 HydrophobicContact CE1-CE2 4.21Å; N231-F234 WeakPolarHBondContact O-CD2 3.22Å; N231-F234 PolarHBondContact O-N 2.94Å; L232-F234 PolarHBondContact O-N 2.99Å; F234-M356 HydrophobicContact CZ-CE 4.13Å; F234-I360 HydrophobicContact CE1-CD1 3.81Å; F234-I360 HydrophobicContact CE1-CG1 4.49Å; F234-I360 HydrophobicContact CZ-CD1 4.47Å; F234-I381 HydrophobicContact CB-CG2 4.43Å; F234-Y384 HydrophobicContact CD2-CE1 4.21Å; F234-Y384 HydrophobicContact CE2-CE1 4.27Å; F234-Y384 HydrophobicContact CG-CE1 4.4Å
235	V	96.1	Very high	94.1	Very high	15 Å²	15	31.2 Å²	31.2	9%	0.091	15%	0.152	C	C	.	.	H	α-helix	trans	-75.5	-46	175.6	179.6	0	0	0	0	110.1	L232 S233 E238 F239 L382 L386	L232-V235 HydrophobicContact CD2-CG2 4.44Å; L232-V235 WeakPolarHBondContact O-CA 3.49Å; L232-V235 WeakPolarHBondContact O-CB 3.48Å; L232-V235 PolarHBondContact O-N 3.17Å; S233-V235 VanDerWaalsContact C-N 3.27Å; S233-V235 PolarHBondContact O-N 3.32Å; V235-E238 PolarHBondContact O-N 2.96Å; V235-F239 HydrophobicContact CG1-CE1 4.29Å; V235-F239 WeakPolarHBondContact O-CD1 3.32Å; V235-F239 WeakPolarHBondContact O-CE1 3.23Å; V235-L382 HydrophobicContact CG1-CD1 3.93Å; V235-L382 HydrophobicContact CG1-CG 4.06Å; V235-L386 HydrophobicContact CG2-CD2 3.87Å; V235-L386 HydrophobicContact CG2-CG 3.81Å
236	F	95.5	Very high	93.9	Very high	82 Å²	82	29.3 Å²	29.3	36%	0.36	14%	0.141	S	C	.	.	H	α-helix	trans	-71.5	-29.1	179.1	-66.6	-63.6	0	0	0	113.1	M75 L232 S233 E238 F239	M75-F236 HydrophobicContact CE-CD2 4Å; M75-F236 HydrophobicContact CE-CE2 3.82Å; M75-F236 HydrophobicContact CG-CD2 4.44Å; M75-F236 HydrophobicContact SD-CD2 3.97Å; M75-F236 HydrophobicContact SD-CE2 3.77Å; L232-F236 HydrophobicContact CB-CD2 4.31Å; L232-F236 HydrophobicContact CB-CE2 4.05Å; L232-F236 WeakPolarHBondContact O-CD2 3.49Å; L232-F236 PolarHBondContact O-N 3.22Å; L232-F236 VanDerWaalsContact O-N 3.13Å; S233-F236 PolarHBondContact O-N 2.88Å; F236-E238 PolarHBondContact O-N 2.95Å; F236-F239 HydrophobicContact CD1-CD2 4.13Å; F236-F239 HydrophobicContact CD1-CE1 4.29Å; F236-F239 AromaticContact CD1-CE2 3.55Å; F236-F239 HydrophobicContact CD1-CE2 3.55Å; F236-F239 AromaticContact CD1-CZ 3.65Å; F236-F239 HydrophobicContact CD1-CZ 3.65Å; F236-F239 AromaticContact CE1-CE2 3.89Å; F236-F239 HydrophobicContact CE1-CE2 3.89Å; F236-F239 AromaticContact CE1-CZ 3.87Å; F236-F239 HydrophobicContact CE1-CZ 3.87Å; F236-F239 WeakPolarHBondContact O-CB 3.48Å; F236-F239 PolarHBondContact O-N 2.91Å
237	A	95.2	Very high	93.5	Very high	3 Å²	3	36.4 Å²	36.4	3%	0.025	18%	0.175	C	C	.	.	H	α-helix	trans	-59.3	-29.2	174	0	0	0	0	0	113.1	S79 M82 G83 S233 F239 P240	S79-A237 WeakPolarHBondContact O-CA 3.39Å; M82-A237 HydrophobicContact CB-CB 3.81Å; G83-A237 WeakPolarHBondContact CA-O 3.43Å; S233-A237 VanDerWaalsContact O-CB 3.26Å; S233-A237 WeakPolarHBondContact O-CB 3.44Å; S233-A237 PolarHBondContact O-N 3.29Å; A237-F239 VanDerWaalsContact C-N 3.33Å; A237-P240 WeakPolarHBondContact O-CD 3.47Å
238	E	94.6	Very high	93.3	Very high	0 Å²	0	38.1 Å²	38.1	0%	0	18%	0.181	C	C	.	.	T	Hydrogen-bonded Turn	trans	-83.2	-6.5	-178.5	-69.6	-62.9	166.5	0	0	113.9	Q86 V235 F236 M241 R242 W378 I381	Q86-E238 PolarHBondContact NE2-OE1 3.42Å; Q86-E238 PolarHBondContact NE2-OE2 3.27Å; Q86-E238 PolarHBondContact OE1-OE1 3.09Å; Q86-E238 VanDerWaalsContact OE1-OE1 3.09Å; V235-E238 PolarHBondContact O-N 2.96Å; F236-E238 PolarHBondContact O-N 2.95Å; E238-M241 PolarHBondContact O-N 3.01Å; E238-R242 WeakPolarHBondContact O-CB 3.44Å; E238-R242 PolarHBondContact O-N 3.29Å; E238-W378 HydrophobicContact CB-CB 4.2Å; E238-W378 HydrophobicContact CG-CB 4.34Å; E238-W378 WeakPolarHBondContact OE2-CA 3.37Å; E238-W378 WeakPolarHBondContact OE2-CB 3.43Å; E238-I381 HydrophobicContact CG-CB 4.13Å; E238-I381 HydrophobicContact CG-CG2 4.03Å; E238-I381 WeakPolarHBondContact OE1-CB 3.16Å; E238-I381 WeakPolarHBondContact OE1-CD1 3.2Å; E238-I381 VanDerWaalsContact OE1-CG2 3.29Å; E238-I381 WeakPolarHBondContact OE1-CG2 3.29Å
239	F	93.7	Very high	93	Very high	92 Å²	92	37 Å²	37	40%	0.404	17%	0.174	S	C	.	.	H	α-helix	trans	-64.1	-44.4	-177.1	-76.5	16.4	0	0	0	113.1	V235 F236 A237 M241 R242 L243	V235-F239 HydrophobicContact CG1-CE1 4.29Å; V235-F239 WeakPolarHBondContact O-CD1 3.32Å; V235-F239 WeakPolarHBondContact O-CE1 3.23Å; F236-F239 HydrophobicContact CD1-CD2 4.13Å; F236-F239 HydrophobicContact CD1-CE1 4.29Å; F236-F239 AromaticContact CD1-CE2 3.55Å; F236-F239 HydrophobicContact CD1-CE2 3.55Å; F236-F239 AromaticContact CD1-CZ 3.65Å; F236-F239 HydrophobicContact CD1-CZ 3.65Å; F236-F239 AromaticContact CE1-CE2 3.89Å; F236-F239 HydrophobicContact CE1-CE2 3.89Å; F236-F239 AromaticContact CE1-CZ 3.87Å; F236-F239 HydrophobicContact CE1-CZ 3.87Å; F236-F239 WeakPolarHBondContact O-CB 3.48Å; F236-F239 PolarHBondContact O-N 2.91Å; A237-F239 VanDerWaalsContact C-N 3.33Å; F239-M241 VanDerWaalsContact C-N 3.33Å; F239-M241 PolarHBondContact O-N 3.07Å; F239-R242 PolarHBondContact O-N 2.87Å; F239-L243 HydrophobicContact CB-CD1 4.37Å; F239-L243 VanDerWaalsContact O-CB 3.29Å; F239-L243 WeakPolarHBondContact O-CB 3.44Å; F239-L243 WeakPolarHBondContact O-CG 3.21Å; F239-L243 PolarHBondContact O-N 3Å
240	P	92.5	Very high	92.7	Very high	12 Å²	12	38.3 Å²	38.3	8%	0.078	18%	0.18	C	C	.	.	H	α-helix	trans	-58.7	-43.4	172.6	-24.1	35.1	0	0	0	112.3	M87 A237 R242 V244 L245 V290 L294	M87-P240 HydrophobicContact SD-CB 4.32Å; A237-P240 WeakPolarHBondContact O-CD 3.47Å; P240-R242 PolarHBondContact O-N 3.35Å; P240-V244 WeakPolarHBondContact O-CB 3.48Å; P240-V244 WeakPolarHBondContact O-CG2 3.45Å; P240-V244 PolarHBondContact O-N 3.41Å; P240-L245 PolarHBondContact O-N 2.98Å; P240-V290 HydrophobicContact CB-CG1 4.26Å; P240-L294 HydrophobicContact CG-CD1 4.22Å; P240-L294 HydrophobicContact CG-CD2 4.16Å
241	M	91	Very high	92.3	Very high	4 Å²	4	44 Å²	44	2%	0.02	21%	0.207	C	C	.	.	H	α-helix	trans	-61.3	-43.4	178.5	-172.7	62.1	177.3	0	0	111.7	T90 E238 F239 L245 H246 L249 I374 W378	T90-M241 HydrophobicContact CG2-CE 4.32Å; E238-M241 PolarHBondContact O-N 3.01Å; F239-M241 VanDerWaalsContact C-N 3.33Å; F239-M241 PolarHBondContact O-N 3.07Å; M241-L245 HydrophobicContact CE-CD2 4.47Å; M241-L245 PolarHBondContact O-N 3.24Å; M241-L245 HydrophobicContact SD-CB 4.08Å; M241-L245 HydrophobicContact SD-CD2 3.78Å; M241-L245 HydrophobicContact SD-CG 4.41Å; M241-H246 PolarHBondContact O-N 3.12Å; M241-H246 VanDerWaalsContact O-N 3.08Å; M241-L249 HydrophobicContact CE-CD1 3.63Å; M241-L249 HydrophobicContact SD-CD1 4.47Å; M241-I374 HydrophobicContact CE-CG2 3.67Å; M241-W378 HydrophobicContact CB-CB 4.39Å; M241-W378 HydrophobicContact CG-CB 4.01Å
242	R	92.9	Very high	91.6	Very high	95 Å²	95	45.7 Å²	45.7	36%	0.358	22%	0.215	S	C	.	.	H	α-helix	trans	-76.6	-43.8	-178.1	175.9	55.3	-176.1	103.9	-8.8	114.4	E238 F239 P240 H246 W378	E238-R242 WeakPolarHBondContact O-CB 3.44Å; E238-R242 PolarHBondContact O-N 3.29Å; F239-R242 PolarHBondContact O-N 2.87Å; P240-R242 PolarHBondContact O-N 3.35Å; R242-H246 PolarHBondContact NH1-CD2 2.94Å; R242-H246 VanDerWaalsContact O-CB 3.23Å; R242-H246 WeakPolarHBondContact O-CB 3.44Å; R242-W378 HydrophobicContact CB-CD2 4.06Å; R242-W378 HydrophobicContact CB-CE3 4.13Å; R242-W378 HydrophobicContact CB-CG 4.3Å; R242-W378 VanDerWaalsContact CD-CE2 3.42Å; R242-W378 VanDerWaalsContact CD-CZ2 3.49Å; R242-W378 HydrophobicContact CG-CD2 4.22Å; R242-W378 HydrophobicContact CG-CE3 4.18Å; R242-W378 HydrophobicContact CG-CH2 4.39Å; R242-W378 HydrophobicContact CG-CZ2 4.43Å; R242-W378 HydrophobicContact CG-CZ3 4.25Å
243	L	90.8	Very high	91.1	Very high	134 Å²	134	47 Å²	47	70%	0.702	23%	0.229	S	C	*	.	H	α-helix	trans	-85.2	-30.5	-172	-63.6	175.6	0	0	0	112.3	F239	F239-L243 HydrophobicContact CB-CD1 4.37Å; F239-L243 VanDerWaalsContact O-CB 3.29Å; F239-L243 WeakPolarHBondContact O-CB 3.44Å; F239-L243 WeakPolarHBondContact O-CG 3.21Å; F239-L243 PolarHBondContact O-N 3Å
244	V	89.1	Confident	90.5	Very high	15 Å²	15	50.4 Å²	50.4	9%	0.091	24%	0.244	C	C	.	.	T	Hydrogen-bonded Turn	trans	-105	-64.1	-174.5	-167.5	0	0	0	0	109.8	P240 H246 Y248 L286 V290	P240-V244 WeakPolarHBondContact O-CB 3.48Å; P240-V244 WeakPolarHBondContact O-CG2 3.45Å; P240-V244 PolarHBondContact O-N 3.41Å; V244-H246 PolarHBondContact O-N 3.43Å; V244-Y248 VanDerWaalsContact O-CD2 3.27Å; V244-Y248 WeakPolarHBondContact O-CD2 3.39Å; V244-L286 HydrophobicContact CG1-CD2 3.9Å; V244-L286 HydrophobicContact CG1-CG 4.03Å; V244-V290 HydrophobicContact CB-CG2 4.48Å; V244-V290 HydrophobicContact CG1-CG2 4.25Å; V244-V290 HydrophobicContact CG2-CB 4.35Å; V244-V290 HydrophobicContact CG2-CG1 4.06Å; V244-V290 HydrophobicContact CG2-CG2 3.42Å; V244-V290 VanDerWaalsContact CG2-CG2 3.42Å
245	L	89.3	Confident	90.1	Very high	5 Å²	5	50.4 Å²	50.4	3%	0.026	25%	0.245	C	C	.	.	G	3₁₀ helix	trans	-78.4	-26	-164.2	-158.2	59.2	0	0	0	113.5	T90 L91 P240 M241 E247 Y248 L249 L278	T90-L245 HydrophobicContact CG2-CD2 3.57Å; L91-L245 HydrophobicContact CD2-CD1 3.77Å; P240-L245 PolarHBondContact O-N 2.98Å; M241-L245 HydrophobicContact CE-CD2 4.47Å; M241-L245 PolarHBondContact O-N 3.24Å; M241-L245 HydrophobicContact SD-CB 4.08Å; M241-L245 HydrophobicContact SD-CD2 3.78Å; M241-L245 HydrophobicContact SD-CG 4.41Å; L245-E247 VanDerWaalsContact C-N 3.26Å; L245-E247 PolarHBondContact O-N 3.38Å; L245-E247 VanDerWaalsContact O-N 3.11Å; L245-Y248 PolarHBondContact O-N 3.04Å; L245-L249 HydrophobicContact CB-CD1 4.39Å; L245-L249 HydrophobicContact CD2-CD1 4.45Å; L245-L249 HydrophobicContact CD2-CD2 4.45Å; L245-L249 HydrophobicContact CG-CD1 4.02Å; L245-L249 HydrophobicContact CG-CD2 4.26Å; L245-L249 HydrophobicContact CG-CG 4.01Å; L245-L249 WeakPolarHBondContact O-CG 3.46Å; L245-L249 PolarHBondContact O-N 3.46Å; L245-L278 HydrophobicContact CD1-CD2 4.13Å
246	H	89.6	Confident	89.6	Confident	33 Å²	33	50.3 Å²	50.3	15%	0.153	24%	0.244	C	C	.	.	G	3₁₀ helix	trans	-51.5	-36.3	-176.9	-176.1	79.6	0	0	0	115.3	M241 R242 V244 K375 W378	M241-H246 PolarHBondContact O-N 3.12Å; M241-H246 VanDerWaalsContact O-N 3.08Å; R242-H246 PolarHBondContact NH1-CD2 2.94Å; R242-H246 VanDerWaalsContact O-CB 3.23Å; R242-H246 WeakPolarHBondContact O-CB 3.44Å; V244-H246 PolarHBondContact O-N 3.43Å; H246-K375 PolarHBondContact CE1-O 2.94Å; H246-K375 PolarHBondContact ND1-O 3.38Å; H246-K375 VanDerWaalsContact O-CE 3.27Å; H246-K375 WeakPolarHBondContact O-CE 3.33Å; H246-W378 AromaticContact ND1-NE1 3.82Å
247	E	89.3	Confident	89	Confident	155 Å²	155	51 Å²	51	72%	0.724	26%	0.258	S	S	*	.	G	3₁₀ helix	trans	-80.1	-26.2	-179.6	-61.3	-164.1	164.4	0	0	113.3	L245	L245-E247 VanDerWaalsContact C-N 3.26Å; L245-E247 PolarHBondContact O-N 3.38Å; L245-E247 VanDerWaalsContact O-N 3.11Å
248	Y	89.9	Confident	88.5	Confident	42 Å²	42	56.2 Å²	56.2	17%	0.165	29%	0.285	C	S	.	.	T	Hydrogen-bonded Turn	trans	-84.2	-18.1	179.2	-64.2	-84.5	0	0	0	113.1	V244 L245 L278 R279 N280 P282 L286	V244-Y248 VanDerWaalsContact O-CD2 3.27Å; V244-Y248 WeakPolarHBondContact O-CD2 3.39Å; L245-Y248 PolarHBondContact O-N 3.04Å; Y248-L278 CarbonylContact O-C 3.49Å; Y248-L278 WeakPolarHBondContact O-CA 3.43Å; Y248-R279 PolarHBondContact O-N 3.03Å; Y248-N280 HydrophobicContact CD1-CB 4.07Å; Y248-N280 WeakPolarHBondContact CD1-O 3.24Å; Y248-P282 HydrophobicContact CD1-CB 4.31Å; Y248-P282 HydrophobicContact CD2-CB 4.42Å; Y248-P282 HydrophobicContact CE1-CB 4.24Å; Y248-P282 HydrophobicContact CE2-CB 4.35Å; Y248-P282 HydrophobicContact CG-CB 4.4Å; Y248-L286 HydrophobicContact CE2-CD2 3.9Å
249	L	90.3	Very high	88.1	Confident	4 Å²	4	56.5 Å²	56.5	2%	0.021	29%	0.287	C	S	.	.	B	Isolated β-bridge	trans	-77.6	138.5	-178.4	-67.8	162.4	0	0	0	112.8	T90 M241 L245 V277 I374 K375	T90-L249 HydrophobicContact CG2-CD2 4.33Å; M241-L249 HydrophobicContact CE-CD1 3.63Å; M241-L249 HydrophobicContact SD-CD1 4.47Å; L245-L249 HydrophobicContact CB-CD1 4.39Å; L245-L249 HydrophobicContact CD2-CD1 4.45Å; L245-L249 HydrophobicContact CD2-CD2 4.45Å; L245-L249 HydrophobicContact CG-CD1 4.02Å; L245-L249 HydrophobicContact CG-CD2 4.26Å; L245-L249 HydrophobicContact CG-CG 4.01Å; L245-L249 WeakPolarHBondContact O-CG 3.46Å; L245-L249 PolarHBondContact O-N 3.46Å; L249-V277 HydrophobicContact CD2-CG1 3.66Å; L249-I374 HydrophobicContact CD1-CG2 4.14Å; L249-I374 HydrophobicContact CD2-CG2 4.05Å; L249-K375 HydrophobicContact CB-CB 4.19Å; L249-K375 HydrophobicContact CB-CG 4.38Å
250	H	88.8	Confident	87.6	Confident	49 Å²	49	60.7 Å²	60.7	23%	0.227	31%	0.305	C	S	.	.	P	Polyproline II helix	trans	-64.1	161	172.7	-95.6	-69	0	0	0	113	H254 V255 V277 L278 R279	H250-H254 HydrophobicContact CB-CB 4.48Å; H250-H254 AromaticContact CD2-ND1 3.69Å; H250-H254 AromaticContact CG-ND1 3.75Å; H250-H254 AromaticContact NE2-ND1 3.94Å; H250-V255 HydrophobicContact CB-CG2 3.71Å; H250-V277 WeakPolarHBondContact CB-O 3.43Å; H250-V277 PolarHBondContact N-O 3.28Å; H250-L278 VanDerWaalsContact CD2-C 3.47Å; H250-L278 PolarHBondContact CD2-O 2.97Å; H250-R279 PolarHBondContact CD2-N 3.46Å; H250-R279 WeakPolarHBondContact NE2-CA 3.2Å
251	E	87.1	Confident	87	Confident	125 Å²	125	63.9 Å²	63.9	58%	0.584	32%	0.324	S	S	*	.	P	Polyproline II helix	trans	-74.4	154	170.6	-66.2	-179.9	-173.4	0	0	112.2	S253 H254 V255	E251-S253 PolarHBondContact O-N 3.39Å; E251-S253 VanDerWaalsContact O-N 3.12Å; E251-H254 PolarHBondContact O-N 3.41Å; E251-H254 VanDerWaalsContact O-N 3.09Å; E251-V255 PolarHBondContact O-N 2.74Å
252	N	82.5	Confident	86.7	Confident	41 Å²	41	63.8 Å²	63.8	22%	0.219	32%	0.324	C	S	.	.	H	α-helix	trans	-57	-32.5	-173.1	-57.3	-1.7	0	0	0	113.1	H254 V255 L256 L372 G373	N252-H254 VanDerWaalsContact C-N 3.33Å; N252-H254 PolarHBondContact O-N 2.95Å; N252-V255 PolarHBondContact O-N 3.2Å; N252-L256 HydrophobicContact CB-CD1 4.15Å; N252-L256 WeakPolarHBondContact O-CB 3.48Å; N252-L256 WeakPolarHBondContact O-CD1 3.45Å; N252-L256 PolarHBondContact O-N 2.68Å; N252-L372 PolarHBondContact ND2-O 2.97Å; N252-L372 PolarHBondContact OD1-O 2.95Å; N252-G373 WeakPolarHBondContact OD1-CA 3.27Å
253	S	83.8	Confident	86.2	Confident	76 Å²	76	59.3 Å²	59.3	53%	0.531	31%	0.307	S	S	.	.	H	α-helix	trans	-58.4	-39.3	178	50.5	0	0	0	0	113.2	E251 C257	E251-S253 PolarHBondContact O-N 3.39Å; E251-S253 VanDerWaalsContact O-N 3.12Å; S253-C257 WeakPolarHBondContact O-CB 3.07Å
254	H	84.8	Confident	85.8	Confident	72 Å²	72	53 Å²	53	33%	0.333	27%	0.274	S	S	.	.	H	α-helix	trans	-79.1	-41.9	177.9	-178.6	-102.9	0	0	0	112	H250 E251 N252 N274	H250-H254 HydrophobicContact CB-CB 4.48Å; H250-H254 AromaticContact CD2-ND1 3.69Å; H250-H254 AromaticContact CG-ND1 3.75Å; H250-H254 AromaticContact NE2-ND1 3.94Å; E251-H254 PolarHBondContact O-N 3.41Å; E251-H254 VanDerWaalsContact O-N 3.09Å; N252-H254 VanDerWaalsContact C-N 3.33Å; N252-H254 PolarHBondContact O-N 2.95Å; H254-N274 PolarHBondContact CE1-ND2 2.72Å; H254-N274 PolarHBondContact O-ND2 2.67Å
255	V	84.8	Confident	85.4	Confident	4 Å²	4	54.7 Å²	54.7	2%	0.024	29%	0.29	C	S	.	.	H	α-helix	trans	-73.7	-34.7	-172.3	175	0	0	0	0	112.2	H250 E251 N252 F273 N274 V277	H250-V255 HydrophobicContact CB-CG2 3.71Å; E251-V255 PolarHBondContact O-N 2.74Å; N252-V255 PolarHBondContact O-N 3.2Å; V255-F273 HydrophobicContact CG1-CD2 4.35Å; V255-F273 HydrophobicContact CG1-CE1 3.78Å; V255-F273 HydrophobicContact CG1-CE2 3.43Å; V255-F273 VanDerWaalsContact CG1-CE2 3.43Å; V255-F273 HydrophobicContact CG1-CZ 3.09Å; V255-N274 WeakPolarHBondContact O-CB 3.43Å; V255-N274 PolarHBondContact O-N 3.29Å; V255-V277 HydrophobicContact CG2-CG1 4.43Å
256	L	85.6	Confident	85.1	Confident	14 Å²	14	54.6 Å²	54.6	7%	0.073	29%	0.289	C	S	.	.	T	Hydrogen-bonded Turn	trans	-105.6	11.8	-177.7	-68.3	99.1	0	0	0	114.4	N252 N258 V259 V369 C370	N252-L256 HydrophobicContact CB-CD1 4.15Å; N252-L256 WeakPolarHBondContact O-CB 3.48Å; N252-L256 WeakPolarHBondContact O-CD1 3.45Å; N252-L256 PolarHBondContact O-N 2.68Å; L256-N258 VanDerWaalsContact C-N 3.28Å; L256-N258 PolarHBondContact O-N 3.1Å; L256-N258 VanDerWaalsContact O-N 3.16Å; L256-V259 HydrophobicContact CB-CB 4.33Å; L256-V259 HydrophobicContact CB-CG2 4.21Å; L256-V259 HydrophobicContact CD2-CG2 4.49Å; L256-V259 HydrophobicContact CG-CG2 4.39Å; L256-V259 WeakPolarHBondContact O-CB 3.43Å; L256-V259 PolarHBondContact O-N 3.25Å; L256-V369 WeakPolarHBondContact CD2-O 3.38Å; L256-C370 HydrophobicContact CD2-CB 4.44Å
257	C	83.9	Confident	84.6	Confident	97 Å²	97	60.7 Å²	60.7	66%	0.655	32%	0.316	S	S	*	.	T	Hydrogen-bonded Turn	trans	-52.5	-40.6	-174.1	-172.3	0	0	0	0	114.2	S253	S253-C257 WeakPolarHBondContact O-CB 3.07Å
258	N	85.3	Confident	83.9	Confident	111 Å²	111	53.6 Å²	53.6	59%	0.594	28%	0.284	S	S	*	.	T	Hydrogen-bonded Turn	trans	-92.4	-2.8	-179	-70.1	-37.1	0	0	0	114	L256 G272	L256-N258 VanDerWaalsContact C-N 3.28Å; L256-N258 PolarHBondContact O-N 3.1Å; L256-N258 VanDerWaalsContact O-N 3.16Å; N258-G272 VanDerWaalsContact CB-O 3.29Å; N258-G272 WeakPolarHBondContact CB-O 3.43Å
259	V	85.3	Confident	82.9	Confident	7 Å²	7	56.7 Å²	56.7	4%	0.042	30%	0.302	C	S	.	.			trans	-81.6	120	-178.1	-176.7	0	0	0	0	109.3	L256 C262 I270 G272 P428	L256-V259 HydrophobicContact CB-CB 4.33Å; L256-V259 HydrophobicContact CB-CG2 4.21Å; L256-V259 HydrophobicContact CD2-CG2 4.49Å; L256-V259 HydrophobicContact CG-CG2 4.39Å; L256-V259 WeakPolarHBondContact O-CB 3.43Å; L256-V259 PolarHBondContact O-N 3.25Å; V259-C262 VanDerWaalsContact CG1-SG 3.58Å; V259-I270 HydrophobicContact CB-CG2 4.38Å; V259-I270 HydrophobicContact CG1-CG2 3.7Å; V259-I270 HydrophobicContact CG2-CG2 3.7Å; V259-G272 WeakPolarHBondContact CG2-O 3.34Å; V259-P428 WeakPolarHBondContact O-CG 3.36Å
260	K	82.3	Confident	82.3	Confident	180 Å²	180	57.2 Å²	57.2	78%	0.783	31%	0.305	S	S	*	.			trans	-104.8	-28.1	-176.4	-63.8	-178.1	-178.1	179	0	114.4
261	T	81.7	Confident	81.6	Confident	79 Å²	79	58 Å²	58	49%	0.485	31%	0.314	S	S	.	.			trans	-144.9	138.6	-174	49.5	0	0	0	0	110.7
262	C	83.8	Confident	81	Confident	2 Å²	2	53.8 Å²	53.8	1%	0.014	30%	0.304	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-132.8	177.1	-176.9	-66.5	0	0	0	0	114.2	V259 I266 C370 V426	V259-C262 VanDerWaalsContact CG1-SG 3.58Å; C262-I266 HydrophobicContact CB-CD1 4.35Å; C262-C370 HydrophobicContact CB-CB 3.49Å; C262-C370 VanDerWaalsContact CB-CB 3.49Å; C262-C370 WeakPolarHBondContact CB-SG 3.12Å; C262-C370 WeakPolarHBondContact SG-CB 3.47Å; C262-C370 CovalentContact SG-SG 2.01Å; C262-C370 PolarHBondContact SG-SG 2.63Å; C262-V426 HydrophobicContact CB-CB 4.01Å; C262-V426 HydrophobicContact CB-CG1 4.14Å; C262-V426 WeakPolarHBondContact CB-O 3.12Å; C262-V426 PolarHBondContact N-O 3.26Å
263	G	83.1	Confident	81.1	Confident	0 Å²	0	53.2 Å²	53.2	0%	0	30%	0.3	C	S	.	.	E	Extended strand (participates in β ladder)	trans	66.9	-132	178.9	0	0	0	0	0	112.2	A265 I266 S366 Y367	G263-A265 PolarHBondContact O-N 3.19Å; G263-I266 PolarHBondContact O-N 2.85Å; G263-I266 VanDerWaalsContact O-N 3.14Å; G263-S366 PolarHBondContact N-O 3.06Å; G263-Y367 VanDerWaalsContact CA-CZ 3.4Å
264	A	81.2	Confident	81.3	Confident	1 Å²	1	51.5 Å²	51.5	1%	0.008	29%	0.285	C	S	.	.	T	Hydrogen-bonded Turn	trans	-57	-27.5	-171.6	0	0	0	0	0	114.3	I266 Y367 R497	A264-I266 VanDerWaalsContact C-N 3.34Å; A264-I266 PolarHBondContact O-N 2.91Å; A264-Y367 WeakPolarHBondContact CA-OH 3.16Å; A264-Y367 PolarHBondContact N-OH 2.77Å; A264-R497 HydrophobicContact CB-CG 4.27Å; A264-R497 WeakPolarHBondContact O-CG 3.34Å; A264-R497 PolarHBondContact O-N 3.41Å
265	A	81.6	Confident	81.2	Confident	52 Å²	52	51 Å²	51	43%	0.43	29%	0.29	S	S	.	.	T	Hydrogen-bonded Turn	trans	-78.3	-10.3	-177.2	0	0	0	0	0	115	G263	G263-A265 PolarHBondContact O-N 3.19Å
266	I	83.4	Confident	81.3	Confident	2 Å²	2	52.7 Å²	52.7	1%	0.01	30%	0.3	C	S	.	.			trans	-68.2	143.9	-176.8	-67.9	173.4	0	0	0	111.8	C262 G263 A264 G268 I270 M496	C262-I266 HydrophobicContact CB-CD1 4.35Å; G263-I266 PolarHBondContact O-N 2.85Å; G263-I266 VanDerWaalsContact O-N 3.14Å; A264-I266 VanDerWaalsContact C-N 3.34Å; A264-I266 PolarHBondContact O-N 2.91Å; I266-G268 WeakPolarHBondContact CG2-O 3.49Å; I266-I270 HydrophobicContact CD1-CG1 4.21Å; I266-M496 HydrophobicContact CB-CB 4.46Å; I266-M496 PolarHBondContact O-N 3.46Å
267	K	78.8	Confident	81.5	Confident	162 Å²	162	52.1 Å²	52.1	70%	0.704	30%	0.297	S	S	*	.	B	Isolated β-bridge	trans	-110.1	127.5	161.8	-59.5	-171	178.9	-180	0	109.3	P495	K267-P495 HydrophobicContact CG-CB 4.24Å
268	G	73.9	Confident	81.7	Confident	5 Å²	5	47.9 Å²	47.9	5%	0.052	27%	0.268	C	S	.	.	S	Bend	trans	68.3	-143.7	-179.8	0	0	0	0	0	114.2	I266 Q493 M494	I266-G268 WeakPolarHBondContact CG2-O 3.49Å; G268-Q493 PolarHBondContact N-O 2.94Å; G268-M494 PolarHBondContact N-O 2.95Å
269	I	70.3	Confident	81.9	Confident	108 Å²	108	50.7 Å²	50.7	55%	0.554	27%	0.27	S	S	*	.	S	Bend	trans	-78.5	152.9	170	-62.1	169.6	0	0	0	108.4	P271	I269-P271 WeakPolarHBondContact O-CD 3.14Å; I269-P271 VanDerWaalsContact O-N 3.07Å
270	I	75.8	Confident	82	Confident	14 Å²	14	55.1 Å²	55.1	7%	0.072	29%	0.293	C	S	.	.			trans	-45.8	114.7	-170.8	-59.1	165.3	0	0	0	111.8	V259 I266 F273 L365 V369	V259-I270 HydrophobicContact CB-CG2 4.38Å; V259-I270 HydrophobicContact CG1-CG2 3.7Å; V259-I270 HydrophobicContact CG2-CG2 3.7Å; I266-I270 HydrophobicContact CD1-CG1 4.21Å; I270-F273 HydrophobicContact CB-CB 4.24Å; I270-F273 HydrophobicContact CB-CD2 4.33Å; I270-F273 HydrophobicContact CD1-CD2 3.97Å; I270-F273 HydrophobicContact CD1-CE2 4.33Å; I270-F273 HydrophobicContact CG2-CB 4.36Å; I270-F273 HydrophobicContact CG2-CD2 4.36Å; I270-F273 WeakPolarHBondContact O-CB 3.45Å; I270-F273 PolarHBondContact O-N 3.33Å; I270-L365 WeakPolarHBondContact CD1-O 3.37Å; I270-V369 HydrophobicContact CD1-CB 4.05Å; I270-V369 HydrophobicContact CD1-CG1 3.8Å
271	P	75.4	Confident	82.3	Confident	66 Å²	66	50.2 Å²	50.2	43%	0.429	28%	0.275	S	S	.	.	T	Hydrogen-bonded Turn	trans	-71.6	133.3	179.2	28.3	-34.8	0	0	0	110.6	I269 F273	I269-P271 WeakPolarHBondContact O-CD 3.14Å; I269-P271 VanDerWaalsContact O-N 3.07Å; P271-F273 VanDerWaalsContact C-N 3.34Å
272	G	74.2	Confident	82.6	Confident	37 Å²	37	47 Å²	47	38%	0.381	26%	0.256	S	S	.	.	T	Hydrogen-bonded Turn	trans	77.7	16.8	-176.6	0	0	0	0	0	114.2	N258 V259	N258-G272 VanDerWaalsContact CB-O 3.29Å; N258-G272 WeakPolarHBondContact CB-O 3.43Å; V259-G272 WeakPolarHBondContact CG2-O 3.34Å
273	F	84.8	Confident	82.9	Confident	28 Å²	28	56.2 Å²	56.2	12%	0.123	29%	0.291	C	S	.	.			trans	-65.5	139.6	166.9	-159.8	-93.7	0	0	0	110.6	Y93 V255 I270 P271 V277 V369 I374	Y93-F273 HydrophobicContact CD1-CE1 4.38Å; Y93-F273 AromaticContact CE1-CD1 3.55Å; Y93-F273 HydrophobicContact CE1-CD1 3.55Å; Y93-F273 AromaticContact CE1-CE1 3.66Å; Y93-F273 HydrophobicContact CE1-CE1 3.66Å; Y93-F273 AromaticContact CZ-CD1 3.69Å; Y93-F273 WeakPolarHBondContact OH-CD1 3.49Å; V255-F273 HydrophobicContact CG1-CD2 4.35Å; V255-F273 HydrophobicContact CG1-CE1 3.78Å; V255-F273 HydrophobicContact CG1-CE2 3.43Å; V255-F273 VanDerWaalsContact CG1-CE2 3.43Å; V255-F273 HydrophobicContact CG1-CZ 3.09Å; I270-F273 HydrophobicContact CB-CB 4.24Å; I270-F273 HydrophobicContact CB-CD2 4.33Å; I270-F273 HydrophobicContact CD1-CD2 3.97Å; I270-F273 HydrophobicContact CD1-CE2 4.33Å; I270-F273 HydrophobicContact CG2-CB 4.36Å; I270-F273 HydrophobicContact CG2-CD2 4.36Å; I270-F273 WeakPolarHBondContact O-CB 3.45Å; I270-F273 PolarHBondContact O-N 3.33Å; P271-F273 VanDerWaalsContact C-N 3.34Å; F273-V277 HydrophobicContact CE1-CG2 3.8Å; F273-V369 HydrophobicContact CD2-CG1 4.46Å; F273-V369 HydrophobicContact CE2-CG1 3.56Å; F273-V369 HydrophobicContact CZ-CG1 4.25Å; F273-I374 HydrophobicContact CE1-CD1 3.93Å; F273-I374 HydrophobicContact CE2-CD1 4.36Å; F273-I374 HydrophobicContact CZ-CD1 3.38Å; F273-I374 HydrophobicContact CZ-CG1 3.89Å
274	N	87.3	Confident	83.1	Confident	40 Å²	40	60.2 Å²	60.2	21%	0.214	32%	0.319	C	S	.	.			trans	-76.6	136.4	-177.1	-163.5	-5.7	0	0	0	111.5	H254 V255 T276	H254-N274 PolarHBondContact CE1-ND2 2.72Å; H254-N274 PolarHBondContact O-ND2 2.67Å; V255-N274 WeakPolarHBondContact O-CB 3.43Å; V255-N274 PolarHBondContact O-N 3.29Å; N274-T276 PolarHBondContact O-N 2.36Å
275	S	84	Confident	83.4	Confident	62 Å²	62	67 Å²	67	43%	0.434	35%	0.352	S	S	.	.	S	Bend	trans	-72.9	-6.6	-179.6	-43.8	0	0	0	0	114.1	M95	M95-S275 PolarHBondContact N-O 3.02Å; M95-S275 VanDerWaalsContact N-O 3.13Å
276	T	86.9	Confident	83.9	Confident	39 Å²	39	67 Å²	67	24%	0.239	34%	0.344	C	S	.	.			trans	-117.4	120.9	171.3	55.6	0	0	0	0	110.9	D94 T96 N274	D94-T276 WeakPolarHBondContact OD1-CA 3.22Å; T96-T276 HydrophobicContact CG2-CG2 3.95Å; N274-T276 PolarHBondContact O-N 2.36Å
277	V	87.8	Confident	84.2	Confident	3 Å²	3	67.4 Å²	67.4	2%	0.018	35%	0.346	C	S	.	.			trans	-119.4	-28	-174.8	-167.3	0	0	0	0	110.5	Y93 D94 L249 H250 V255 F273 I374	Y93-V277 HydrophobicContact CD1-CG2 3.64Å; Y93-V277 HydrophobicContact CE1-CG2 3.9Å; D94-V277 PolarHBondContact OD1-N 2.59Å; L249-V277 HydrophobicContact CD2-CG1 3.66Å; H250-V277 WeakPolarHBondContact CB-O 3.43Å; H250-V277 PolarHBondContact N-O 3.28Å; V255-V277 HydrophobicContact CG2-CG1 4.43Å; F273-V277 HydrophobicContact CE1-CG2 3.8Å; V277-I374 HydrophobicContact CG1-CB 4.36Å; V277-I374 HydrophobicContact CG1-CD1 4.03Å; V277-I374 HydrophobicContact CG1-CG2 4.36Å
278	L	89.3	Confident	84.7	Confident	7 Å²	7	63.8 Å²	63.8	4%	0.037	33%	0.334	C	S	.	.	B	Isolated β-bridge	trans	-87.3	135.3	174.3	-71.4	94.3	0	0	0	111.3	L91 D94 L245 Y248 H250 P282	L91-L278 HydrophobicContact CD2-CD2 3.99Å; D94-L278 HydrophobicContact CB-CD1 3.4Å; D94-L278 VanDerWaalsContact CB-CD1 3.4Å; D94-L278 PolarHBondContact OD1-N 3.08Å; L245-L278 HydrophobicContact CD1-CD2 4.13Å; Y248-L278 CarbonylContact O-C 3.49Å; Y248-L278 WeakPolarHBondContact O-CA 3.43Å; H250-L278 VanDerWaalsContact CD2-C 3.47Å; H250-L278 PolarHBondContact CD2-O 2.97Å; L278-P282 HydrophobicContact CD2-CG 4.2Å
279	R	89.2	Confident	85.7	Confident	171 Å²	171	69.2 Å²	69.2	65%	0.645	36%	0.358	S	S	*	.	S	Bend	trans	-79.3	-42	172.2	178.6	-176.9	178.3	176.4	2.2	111.8	Y248 H250	Y248-R279 PolarHBondContact O-N 3.03Å; H250-R279 PolarHBondContact CD2-N 3.46Å; H250-R279 WeakPolarHBondContact NE2-CA 3.2Å
280	N	88.5	Confident	86.7	Confident	99 Å²	99	64.8 Å²	64.8	53%	0.529	34%	0.336	S	S	.	.	S	Bend	trans	-133.1	147.1	-179.7	-68.3	-25.4	0	0	0	107.9	Y248	Y248-N280 HydrophobicContact CD1-CB 4.07Å; Y248-N280 WeakPolarHBondContact CD1-O 3.24Å
281	L	87.7	Confident	87.5	Confident	77 Å²	77	64.5 Å²	64.5	40%	0.403	33%	0.334	S	S	.	.	P	Polyproline II helix	trans	-73	130.9	175.1	-156.9	72.5	0	0	0	110.3	Y97 V100	Y97-L281 HydrophobicContact CD2-CD1 3.7Å; Y97-L281 HydrophobicContact CD2-CG 4.47Å; Y97-L281 HydrophobicContact CG-CD1 4.3Å; V100-L281 HydrophobicContact CG1-CD2 4.13Å
282	P	88.2	Confident	88.4	Confident	13 Å²	13	63.9 Å²	63.9	8%	0.084	33%	0.331	C	S	.	.	P	Polyproline II helix	trans	-65.9	142.6	175.8	27.2	-34.2	0	0	0	110.5	L91 Y97 Y248 L278 S284	L91-P282 HydrophobicContact CD2-CG 4.02Å; Y97-P282 HydrophobicContact CD2-CG 4.49Å; Y97-P282 HydrophobicContact CE2-CG 4.32Å; Y248-P282 HydrophobicContact CD1-CB 4.31Å; Y248-P282 HydrophobicContact CD2-CB 4.42Å; Y248-P282 HydrophobicContact CE1-CB 4.24Å; Y248-P282 HydrophobicContact CE2-CB 4.35Å; Y248-P282 HydrophobicContact CG-CB 4.4Å; L278-P282 HydrophobicContact CD2-CG 4.2Å; P282-S284 PolarHBondContact O-N 3.44Å
283	R	88.9	Confident	89.4	Confident	195 Å²	195	66.4 Å²	66.4	74%	0.736	34%	0.335	S	S	*	.	P	Polyproline II helix	trans	-67.7	133.2	177.5	-67.3	-179.5	178	173.7	-0.3	109.3	M285 L286 L287	R283-M285 PolarHBondContact O-N 2.97Å; R283-L286 HydrophobicContact CB-CB 4.49Å; R283-L286 WeakPolarHBondContact O-CB 3.39Å; R283-L286 PolarHBondContact O-N 3.18Å; R283-L287 PolarHBondContact O-N 2.94Å
284	S	87.6	Confident	89.9	Confident	84 Å²	84	65.9 Å²	65.9	59%	0.587	33%	0.333	S	S	*	.	H	α-helix	trans	-53.3	-40.7	178.9	49.6	0	0	0	0	113.1	P282 L286 L287 I288	P282-S284 PolarHBondContact O-N 3.44Å; S284-L286 VanDerWaalsContact C-N 3.34Å; S284-L286 PolarHBondContact O-N 3.36Å; S284-L287 PolarHBondContact O-N 2.83Å; S284-I288 WeakPolarHBondContact O-CG1 3.31Å; S284-I288 PolarHBondContact O-N 3.23Å
285	M	89.2	Confident	90.3	Very high	144 Å²	144	64.7 Å²	64.7	71%	0.709	33%	0.327	S	S	*	.	H	α-helix	trans	-57.9	-42	176.7	-65.6	-60.8	-65.7	0	0	113	R283 I288 E289	R283-M285 PolarHBondContact O-N 2.97Å; M285-I288 PolarHBondContact O-N 2.92Å; M285-E289 WeakPolarHBondContact O-CB 3.42Å; M285-E289 PolarHBondContact O-N 3.46Å
286	L	90.9	Very high	90.9	Very high	51 Å²	51	63.7 Å²	63.7	27%	0.267	33%	0.326	S	S	.	.	H	α-helix	trans	-67.5	-37.9	179.5	179	64.8	0	0	0	111.2	V244 Y248 R283 S284 V290	V244-L286 HydrophobicContact CG1-CD2 3.9Å; V244-L286 HydrophobicContact CG1-CG 4.03Å; Y248-L286 HydrophobicContact CE2-CD2 3.9Å; R283-L286 HydrophobicContact CB-CB 4.49Å; R283-L286 WeakPolarHBondContact O-CB 3.39Å; R283-L286 PolarHBondContact O-N 3.18Å; S284-L286 VanDerWaalsContact C-N 3.34Å; S284-L286 PolarHBondContact O-N 3.36Å; L286-V290 HydrophobicContact CD1-CG2 4.48Å; L286-V290 WeakPolarHBondContact O-CG2 3.41Å; L286-V290 PolarHBondContact O-N 3.41Å; L286-V290 VanDerWaalsContact O-N 3.12Å
287	L	89.1	Confident	91.3	Very high	11 Å²	11	66.6 Å²	66.6	6%	0.058	34%	0.336	C	S	.	.	H	α-helix	trans	-67.4	-45.3	178.5	-159.4	71.1	0	0	0	111.1	M87 L91 Y97 R283 S284 E289 V290 E291	M87-L287 HydrophobicContact CE-CD1 3.88Å; M87-L287 HydrophobicContact SD-CD1 3.9Å; L91-L287 HydrophobicContact CD1-CD1 3.73Å; L91-L287 HydrophobicContact CD1-CD2 4.17Å; Y97-L287 VanDerWaalsContact OH-CD2 3.29Å; Y97-L287 WeakPolarHBondContact OH-CD2 3.32Å; R283-L287 PolarHBondContact O-N 2.94Å; S284-L287 PolarHBondContact O-N 2.83Å; L287-E289 VanDerWaalsContact C-N 3.34Å; L287-E289 PolarHBondContact O-N 3.32Å; L287-V290 PolarHBondContact O-N 2.77Å; L287-E291 WeakPolarHBondContact O-CG 3.41Å; L287-E291 PolarHBondContact O-N 2.8Å
288	I	91	Very high	91.7	Very high	86 Å²	86	66.8 Å²	66.8	44%	0.441	34%	0.337	S	S	.	.	H	α-helix	trans	-63	-39.5	176.5	-66	165.2	0	0	0	111.4	S284 M285 S292	S284-I288 WeakPolarHBondContact O-CG1 3.31Å; S284-I288 PolarHBondContact O-N 3.23Å; M285-I288 PolarHBondContact O-N 2.92Å; I288-S292 VanDerWaalsContact O-CB 3.31Å; I288-S292 WeakPolarHBondContact O-CB 3.27Å; I288-S292 PolarHBondContact O-N 3.43Å; I288-S292 PolarHBondContact O-OG 2.82Å
289	E	92.9	Very high	92	Very high	118 Å²	118	71.2 Å²	71.2	55%	0.551	36%	0.357	S	S	*	.	H	α-helix	trans	-60.5	-47.2	176	-178	177.7	-177.3	0	0	111.4	M285 L287 S292 I293	M285-E289 WeakPolarHBondContact O-CB 3.42Å; M285-E289 PolarHBondContact O-N 3.46Å; L287-E289 VanDerWaalsContact C-N 3.34Å; L287-E289 PolarHBondContact O-N 3.32Å; E289-S292 WeakPolarHBondContact O-CB 3.19Å; E289-S292 PolarHBondContact O-N 3.15Å; E289-I293 HydrophobicContact CG-CD1 4.32Å; E289-I293 WeakPolarHBondContact O-CG1 3.3Å; E289-I293 PolarHBondContact O-N 2.88Å
290	V	92.6	Very high	92.4	Very high	16 Å²	16	66.9 Å²	66.9	10%	0.097	35%	0.346	C	S	.	.	H	α-helix	trans	-66.2	-43.9	179.4	172.8	0	0	0	0	111.5	M87 P240 V244 L286 L287 S292 I293 L294	M87-V290 HydrophobicContact SD-CG1 4.34Å; P240-V290 HydrophobicContact CB-CG1 4.26Å; V244-V290 HydrophobicContact CB-CG2 4.48Å; V244-V290 HydrophobicContact CG1-CG2 4.25Å; V244-V290 HydrophobicContact CG2-CB 4.35Å; V244-V290 HydrophobicContact CG2-CG1 4.06Å; V244-V290 HydrophobicContact CG2-CG2 3.42Å; V244-V290 VanDerWaalsContact CG2-CG2 3.42Å; L286-V290 HydrophobicContact CD1-CG2 4.48Å; L286-V290 WeakPolarHBondContact O-CG2 3.41Å; L286-V290 PolarHBondContact O-N 3.41Å; L286-V290 VanDerWaalsContact O-N 3.12Å; L287-V290 PolarHBondContact O-N 2.77Å; V290-S292 PolarHBondContact O-N 2.96Å; V290-I293 PolarHBondContact O-N 2.74Å; V290-L294 HydrophobicContact CG1-CD1 4.29Å; V290-L294 WeakPolarHBondContact O-CG 3.27Å; V290-L294 PolarHBondContact O-N 3.45Å
291	E	91.9	Very high	92.7	Very high	8 Å²	8	62.1 Å²	62.1	4%	0.037	32%	0.321	C	S	.	.	H	α-helix	trans	-62.1	-34.1	174.4	-72.2	176.5	165.5	0	0	111.8	L84 M87 Q88 Y157 L287 L294 M295	L84-E291 HydrophobicContact CD1-CG 4.39Å; M87-E291 HydrophobicContact CE-CG 4.01Å; Q88-E291 PolarHBondContact NE2-OE1 3.4Å; Y157-E291 HydrophobicContact CD1-CB 4.1Å; Y157-E291 HydrophobicContact CE1-CB 3.75Å; L287-E291 WeakPolarHBondContact O-CG 3.41Å; L287-E291 PolarHBondContact O-N 2.8Å; E291-L294 PolarHBondContact O-N 3.45Å; E291-M295 WeakPolarHBondContact O-CB 3.43Å; E291-M295 PolarHBondContact O-N 2.94Å
292	S	94.6	Very high	93.1	Very high	52 Å²	52	60.4 Å²	60.4	36%	0.364	31%	0.311	S	S	.	.	H	α-helix	trans	-69.4	-39.3	174.8	-56.8	0	0	0	0	113.3	Y157 I288 E289 V290 M295 G296	Y157-S292 WeakPolarHBondContact OH-CA 3.36Å; Y157-S292 PolarHBondContact OH-OG 3.47Å; I288-S292 VanDerWaalsContact O-CB 3.31Å; I288-S292 WeakPolarHBondContact O-CB 3.27Å; I288-S292 PolarHBondContact O-N 3.43Å; I288-S292 PolarHBondContact O-OG 2.82Å; E289-S292 WeakPolarHBondContact O-CB 3.19Å; E289-S292 PolarHBondContact O-N 3.15Å; V290-S292 PolarHBondContact O-N 2.96Å; S292-M295 PolarHBondContact O-N 3.08Å; S292-G296 PolarHBondContact O-N 3.5Å
293	I	95.3	Very high	93.5	Very high	91 Å²	91	63.4 Å²	63.4	47%	0.467	33%	0.326	S	S	.	.	H	α-helix	trans	-63.4	-45.4	172.4	-67.8	164.8	0	0	0	110.1	E289 V290 M295 G296 F297	E289-I293 HydrophobicContact CG-CD1 4.32Å; E289-I293 WeakPolarHBondContact O-CG1 3.3Å; E289-I293 PolarHBondContact O-N 2.88Å; V290-I293 PolarHBondContact O-N 2.74Å; I293-M295 PolarHBondContact O-N 3.27Å; I293-G296 PolarHBondContact O-N 3.34Å; I293-F297 HydrophobicContact CG2-CD2 3.88Å; I293-F297 HydrophobicContact CG2-CE2 3.6Å; I293-F297 WeakPolarHBondContact O-CD2 3.4Å; I293-F297 PolarHBondContact O-N 2.08Å
294	L	95	Very high	93.8	Very high	16 Å²	16	55.2 Å²	55.2	8%	0.084	30%	0.296	C	S	.	.	H	α-helix	trans	-61	-41.7	176	-72.3	174.1	0	0	0	112.2	V80 L84 P240 V290 E291 F297 A298	V80-L294 HydrophobicContact CB-CD2 4.48Å; V80-L294 HydrophobicContact CG1-CB 4.11Å; V80-L294 HydrophobicContact CG1-CD2 4.33Å; V80-L294 HydrophobicContact CG2-CD2 4.09Å; L84-L294 HydrophobicContact CB-CD1 4.48Å; P240-L294 HydrophobicContact CG-CD1 4.22Å; P240-L294 HydrophobicContact CG-CD2 4.16Å; V290-L294 HydrophobicContact CG1-CD1 4.29Å; V290-L294 WeakPolarHBondContact O-CG 3.27Å; V290-L294 PolarHBondContact O-N 3.45Å; E291-L294 PolarHBondContact O-N 3.45Å; L294-F297 PolarHBondContact O-N 3.4Å; L294-A298 PolarHBondContact O-N 3.31Å
295	M	95.5	Very high	94.1	Very high	15 Å²	15	51.2 Å²	51.2	7%	0.074	27%	0.268	C	S	.	.	H	α-helix	trans	-64.5	-39.3	175.1	-168.5	67.2	-164.5	0	0	111.9	A150 V153 Y157 E291 S292 I293 F297 A298 F299	A150-M295 HydrophobicContact CB-CE 4.08Å; A150-M295 WeakPolarHBondContact O-CE 3.23Å; A150-M295 VanDerWaalsContact O-SD 3.41Å; V153-M295 HydrophobicContact CB-SD 3.8Å; V153-M295 HydrophobicContact CG1-CB 4.1Å; V153-M295 HydrophobicContact CG1-SD 3.73Å; Y157-M295 HydrophobicContact CE2-CG 4.43Å; E291-M295 WeakPolarHBondContact O-CB 3.43Å; E291-M295 PolarHBondContact O-N 2.94Å; S292-M295 PolarHBondContact O-N 3.08Å; I293-M295 PolarHBondContact O-N 3.27Å; M295-F297 VanDerWaalsContact C-N 3.35Å; M295-F297 PolarHBondContact O-N 2.8Å; M295-A298 PolarHBondContact O-N 3.28Å; M295-F299 HydrophobicContact CE-CD2 3.8Å; M295-F299 HydrophobicContact CE-CE1 4.47Å; M295-F299 HydrophobicContact CE-CE2 3.23Å; M295-F299 HydrophobicContact CE-CZ 3.62Å; M295-F299 HydrophobicContact CG-CD2 4.01Å; M295-F299 HydrophobicContact CG-CE2 3.92Å; M295-F299 WeakPolarHBondContact O-CD2 3.15Å; M295-F299 PolarHBondContact O-N 3.39Å; M295-F299 HydrophobicContact SD-CE2 4.4Å
296	G	96.4	Very high	94.3	Very high	41 Å²	41	47.2 Å²	47.2	42%	0.423	25%	0.249	S	C	.	.	H	α-helix	trans	-59	-43.4	173.2	0	0	0	0	0	112.6	S292 I293 F299 L300	S292-G296 PolarHBondContact O-N 3.5Å; I293-G296 PolarHBondContact O-N 3.34Å; G296-F299 PolarHBondContact O-N 3.09Å; G296-L300 WeakPolarHBondContact O-CB 3.36Å; G296-L300 PolarHBondContact O-N 3.17Å
297	F	96.6	Very high	94.4	Very high	101 Å²	101	50.7 Å²	50.7	44%	0.443	27%	0.267	S	S	.	.	H	α-helix	trans	-66.7	-37.5	173.6	-76.9	-63.1	0	0	0	113.1	I76 V80 I293 L294 M295 L300 A301	I76-F297 HydrophobicContact CG2-CB 3.88Å; I76-F297 VanDerWaalsContact CG2-O 3.26Å; I76-F297 WeakPolarHBondContact CG2-O 3.42Å; V80-F297 HydrophobicContact CG2-CB 3.81Å; I293-F297 HydrophobicContact CG2-CD2 3.88Å; I293-F297 HydrophobicContact CG2-CE2 3.6Å; I293-F297 WeakPolarHBondContact O-CD2 3.4Å; I293-F297 PolarHBondContact O-N 2.08Å; L294-F297 PolarHBondContact O-N 3.4Å; M295-F297 VanDerWaalsContact C-N 3.35Å; M295-F297 PolarHBondContact O-N 2.8Å; F297-L300 HydrophobicContact CD1-CD2 4.26Å; F297-L300 PolarHBondContact O-N 3.37Å; F297-A301 PolarHBondContact O-N 2.97Å
298	A	95.9	Very high	94.6	Very high	6 Å²	6	53.6 Å²	53.6	5%	0.05	28%	0.282	C	S	.	.	H	α-helix	trans	-62.1	-44.5	174.4	0	0	0	0	0	112	V80 A150 L294 M295 A301 M302	V80-A298 HydrophobicContact CG1-CB 4.36Å; A150-A298 HydrophobicContact CB-CB 3.93Å; L294-A298 PolarHBondContact O-N 3.31Å; M295-A298 PolarHBondContact O-N 3.28Å; A298-A301 PolarHBondContact O-N 3.11Å; A298-M302 PolarHBondContact O-N 2.81Å; A298-M302 VanDerWaalsContact O-N 3.09Å
299	F	96.2	Very high	94.5	Very high	100 Å²	100	49.6 Å²	49.6	44%	0.439	26%	0.262	S	S	.	.	H	α-helix	trans	-62.6	-42.1	173	-86.1	-63.4	0	0	0	112.5	M295 G296 A301 M302 I303	M295-F299 HydrophobicContact CE-CD2 3.8Å; M295-F299 HydrophobicContact CE-CE1 4.47Å; M295-F299 HydrophobicContact CE-CE2 3.23Å; M295-F299 HydrophobicContact CE-CZ 3.62Å; M295-F299 HydrophobicContact CG-CD2 4.01Å; M295-F299 HydrophobicContact CG-CE2 3.92Å; M295-F299 WeakPolarHBondContact O-CD2 3.15Å; M295-F299 PolarHBondContact O-N 3.39Å; M295-F299 HydrophobicContact SD-CE2 4.4Å; G296-F299 PolarHBondContact O-N 3.09Å; F299-A301 VanDerWaalsContact C-N 3.32Å; F299-A301 PolarHBondContact O-N 3.04Å; F299-M302 HydrophobicContact CD1-CE 3.78Å; F299-M302 HydrophobicContact CE1-CE 4.12Å; F299-M302 WeakPolarHBondContact O-CB 3.2Å; F299-M302 PolarHBondContact O-N 2.92Å; F299-I303 WeakPolarHBondContact O-CG1 3.47Å; F299-I303 PolarHBondContact O-N 3.39Å
300	L	96.2	Very high	94.1	Very high	80 Å²	80	44.8 Å²	44.8	42%	0.419	24%	0.244	S	C	.	.	H	α-helix	trans	-58.5	-43.7	175.8	179.4	63.2	0	0	0	111.5	G296 F297 I303 I304	G296-L300 WeakPolarHBondContact O-CB 3.36Å; G296-L300 PolarHBondContact O-N 3.17Å; F297-L300 HydrophobicContact CD1-CD2 4.26Å; F297-L300 PolarHBondContact O-N 3.37Å; L300-I303 PolarHBondContact O-N 3.31Å; L300-I304 HydrophobicContact CD1-CD1 4.5Å; L300-I304 HydrophobicContact CG-CD1 4.13Å; L300-I304 VanDerWaalsContact O-CG1 3.29Å; L300-I304 WeakPolarHBondContact O-CG1 3.27Å; L300-I304 PolarHBondContact O-N 3.03Å
301	A	95.7	Very high	93.5	Very high	0 Å²	0	48.4 Å²	48.4	0%	0	27%	0.268	C	S	.	.	H	α-helix	trans	-64.3	-40.4	177.3	0	0	0	0	0	112.7	I76 V77 F297 A298 F299 I303 I304 F305	I76-A301 HydrophobicContact CB-CB 3.93Å; I76-A301 HydrophobicContact CG2-CB 3.84Å; V77-A301 HydrophobicContact CG2-CB 3.68Å; F297-A301 PolarHBondContact O-N 2.97Å; A298-A301 PolarHBondContact O-N 3.11Å; F299-A301 VanDerWaalsContact C-N 3.32Å; F299-A301 PolarHBondContact O-N 3.04Å; A301-I303 VanDerWaalsContact C-N 3.34Å; A301-I303 PolarHBondContact O-N 3.23Å; A301-I304 WeakPolarHBondContact O-CB 3.06Å; A301-I304 PolarHBondContact O-N 3.03Å; A301-F305 WeakPolarHBondContact O-CD2 3.41Å; A301-F305 PolarHBondContact O-N 3.2Å
302	M	95.4	Very high	92.6	Very high	40 Å²	40	48.3 Å²	48.3	20%	0.197	27%	0.268	C	S	.	.	H	α-helix	trans	-61.4	-41.6	174.1	-173	-172.1	77.3	0	0	111.7	F143 A298 F299 F305 L306	F143-M302 HydrophobicContact CD2-CG 3.83Å; F143-M302 HydrophobicContact CE2-CE 4.5Å; F143-M302 HydrophobicContact CE2-CG 3.47Å; F143-M302 VanDerWaalsContact CE2-CG 3.47Å; F143-M302 HydrophobicContact CE2-SD 4.12Å; F143-M302 HydrophobicContact CZ-CG 4.26Å; F143-M302 HydrophobicContact CZ-SD 4.37Å; A298-M302 PolarHBondContact O-N 2.81Å; A298-M302 VanDerWaalsContact O-N 3.09Å; F299-M302 HydrophobicContact CD1-CE 3.78Å; F299-M302 HydrophobicContact CE1-CE 4.12Å; F299-M302 WeakPolarHBondContact O-CB 3.2Å; F299-M302 PolarHBondContact O-N 2.92Å; M302-F305 PolarHBondContact O-N 3.06Å; M302-L306 PolarHBondContact O-N 3.48Å
303	I	95.7	Very high	91.4	Very high	77 Å²	77	46.7 Å²	46.7	40%	0.395	25%	0.254	S	S	.	.	H	α-helix	trans	-64	-38.9	174.3	-68.2	166.7	0	0	0	111.2	F299 L300 A301 L306 L307	F299-I303 WeakPolarHBondContact O-CG1 3.47Å; F299-I303 PolarHBondContact O-N 3.39Å; L300-I303 PolarHBondContact O-N 3.31Å; A301-I303 VanDerWaalsContact C-N 3.34Å; A301-I303 PolarHBondContact O-N 3.23Å; I303-L306 PolarHBondContact O-N 3.35Å; I303-L307 HydrophobicContact CG2-CD1 3.66Å; I303-L307 HydrophobicContact CG2-CG 4.12Å; I303-L307 WeakPolarHBondContact O-CB 3.39Å; I303-L307 PolarHBondContact O-N 2.99Å
304	I	95.3	Very high	89.9	Confident	22 Å²	22	46.3 Å²	46.3	11%	0.113	25%	0.247	C	C	.	.	I	π-helix	trans	-61.9	-44.3	176.1	-69.9	163.8	0	0	0	111.3	A69 I76 L300 A301 L306 L308 C309	A69-I304 HydrophobicContact CB-CG2 4Å; A69-I304 WeakPolarHBondContact O-CG2 3.47Å; I76-I304 HydrophobicContact CD1-CD1 4.01Å; L300-I304 HydrophobicContact CD1-CD1 4.5Å; L300-I304 HydrophobicContact CG-CD1 4.13Å; L300-I304 VanDerWaalsContact O-CG1 3.29Å; L300-I304 WeakPolarHBondContact O-CG1 3.27Å; L300-I304 PolarHBondContact O-N 3.03Å; A301-I304 WeakPolarHBondContact O-CB 3.06Å; A301-I304 PolarHBondContact O-N 3.03Å; I304-L306 VanDerWaalsContact C-N 3.35Å; I304-L308 HydrophobicContact CB-CD1 4.48Å; I304-L308 HydrophobicContact CG1-CD1 4.28Å; I304-L308 HydrophobicContact CG2-CB 4.43Å; I304-L308 WeakPolarHBondContact O-CB 3.3Å; I304-L308 PolarHBondContact O-N 3.45Å; I304-C309 PolarHBondContact O-N 3.43Å
305	F	94	Very high	88.7	Confident	1 Å²	1	50.1 Å²	50.1	0%	0.004	27%	0.273	C	S	.	.	I	π-helix	trans	-66.4	-34.7	175.4	-71.4	-58.3	0	0	0	113.1	G73 A74 V77 K139 M142 F143 F178 A301 M302 C309	G73-F305 VanDerWaalsContact C-CZ 3.45Å; A74-F305 HydrophobicContact CB-CZ 4.4Å; V77-F305 HydrophobicContact CG2-CE2 4Å; K139-F305 WeakPolarHBondContact CE-O 3.27Å; M142-F305 HydrophobicContact CB-CD1 4.33Å; M142-F305 HydrophobicContact CE-CD1 3.65Å; M142-F305 HydrophobicContact CE-CE1 3.41Å; M142-F305 VanDerWaalsContact CE-CE1 3.41Å; M142-F305 HydrophobicContact CE-CZ 4.46Å; F143-F305 HydrophobicContact CB-CB 4.48Å; F178-F305 HydrophobicContact CE2-CE2 4.28Å; F178-F305 HydrophobicContact CE2-CZ 4.15Å; F178-F305 HydrophobicContact CZ-CZ 4.38Å; A301-F305 WeakPolarHBondContact O-CD2 3.41Å; A301-F305 PolarHBondContact O-N 3.2Å; M302-F305 PolarHBondContact O-N 3.06Å; F305-C309 WeakPolarHBondContact O-CB 3.23Å
306	L	93.5	Very high	87.1	Confident	60 Å²	60	53.4 Å²	53.4	31%	0.314	29%	0.294	S	S	.	.	I	π-helix	trans	-72.6	-51.8	178.8	-171.3	63.8	0	0	0	112.6	K139 W140 F143 M302 I303 I304	K139-L306 WeakPolarHBondContact CE-O 3.45Å; K139-L306 PolarHBondContact NZ-O 3.3Å; W140-L306 HydrophobicContact CH2-CD1 4.31Å; W140-L306 HydrophobicContact CZ3-CD1 3.83Å; F143-L306 HydrophobicContact CD2-CB 3.81Å; F143-L306 HydrophobicContact CD2-CD1 4.05Å; F143-L306 HydrophobicContact CD2-CG 4.41Å; F143-L306 HydrophobicContact CE2-CB 3.78Å; F143-L306 HydrophobicContact CE2-CD1 3.89Å; F143-L306 HydrophobicContact CE2-CD2 4.02Å; F143-L306 HydrophobicContact CE2-CG 4.11Å; F143-L306 HydrophobicContact CG-CD1 4.47Å; F143-L306 HydrophobicContact CZ-CD1 4.21Å; F143-L306 HydrophobicContact CZ-CD2 4.41Å; M302-L306 PolarHBondContact O-N 3.48Å; I303-L306 PolarHBondContact O-N 3.35Å; I304-L306 VanDerWaalsContact C-N 3.35Å
307	L	93.6	Very high	85.9	Confident	123 Å²	123	52.8 Å²	52.8	64%	0.644	28%	0.28	S	S	*	.	I	π-helix	trans	-95.1	-38.8	-167.8	-58.7	-175	0	0	0	113.9	I303	I303-L307 HydrophobicContact CG2-CD1 3.66Å; I303-L307 HydrophobicContact CG2-CG 4.12Å; I303-L307 WeakPolarHBondContact O-CB 3.39Å; I303-L307 PolarHBondContact O-N 2.99Å
308	L	92.6	Very high	84.6	Confident	72 Å²	72	51.7 Å²	51.7	38%	0.377	28%	0.276	S	S	.	.	I	π-helix	trans	-91.5	-25.8	-173.1	-74.4	90.4	0	0	0	113.6	N66 A69 I304	N66-L308 PolarHBondContact OD1-O 2.62Å; N66-L308 VanDerWaalsContact OD1-O 3.13Å; A69-L308 HydrophobicContact CB-CB 3.56Å; A69-L308 HydrophobicContact CB-CD2 4.22Å; I304-L308 HydrophobicContact CB-CD1 4.48Å; I304-L308 HydrophobicContact CG1-CD1 4.28Å; I304-L308 HydrophobicContact CG2-CB 4.43Å; I304-L308 WeakPolarHBondContact O-CB 3.3Å; I304-L308 PolarHBondContact O-N 3.45Å
309	C	89.4	Confident	83.2	Confident	3 Å²	3	56.9 Å²	56.9	2%	0.02	30%	0.302	C	S	.	.	P	Polyproline II helix	trans	-83.9	120.2	178.9	-61.3	0	0	0	0	111.3	K139 Y185 I304 F305	K139-C309 WeakPolarHBondContact CD-O 3.42Å; K139-C309 WeakPolarHBondContact CE-O 3.22Å; K139-C309 PolarHBondContact NZ-O 3.35Å; Y185-C309 WeakPolarHBondContact OH-CB 3.13Å; I304-C309 PolarHBondContact O-N 3.43Å; F305-C309 WeakPolarHBondContact O-CB 3.23Å
310	G	83.9	Confident	81.9	Confident	16 Å²	16	54.6 Å²	54.6	17%	0.165	29%	0.294	C	S	.	.	P	Polyproline II helix	trans	-75.4	169.4	171.2	0	0	0	0	0	113.8	N66 Y185	N66-G310 PolarHBondContact OD1-N 2.83Å; Y185-G310 WeakPolarHBondContact CE2-O 3.42Å; Y185-G310 PolarHBondContact OH-N 3.1Å; Y185-G310 PolarHBondContact OH-O 3.04Å
311	P	80.6	Confident	80.7	Confident	93 Å²	93	51.4 Å²	51.4	60%	0.604	28%	0.278	S	S	*	.	P	Polyproline II helix	trans	-64.4	143.2	174.7	28.8	-35	0	0	0	111.6	M189	M189-P311 VanDerWaalsContact CE-O 3.32Å; M189-P311 WeakPolarHBondContact CE-O 3.3Å
312	A	72.6	Confident	79.5	Confident	5 Å²	5	57.5 Å²	57.5	4%	0.041	30%	0.301	C	S	.	.	S	Bend	trans	-94.4	-23.8	-176.5	0	0	0	0	0	114.5	I138 Y185 R188 M189 Q192	I138-A312 HydrophobicContact CB-CB 4.4Å; I138-A312 HydrophobicContact CD1-CB 4.38Å; Y185-A312 HydrophobicContact CD2-CB 3.66Å; Y185-A312 HydrophobicContact CE2-CB 3.83Å; R188-A312 HydrophobicContact CG-CB 4.43Å; R188-A312 WeakPolarHBondContact CG-O 3.47Å; M189-A312 HydrophobicContact CE-CB 4.29Å; Q192-A312 PolarHBondContact NE2-O 3.37Å
313	Y	69.1	Low	78.3	Confident	18 Å²	18	57.8 Å²	57.8	7%	0.071	31%	0.307	C	S	.	.	S	Bend	trans	-114.3	157.6	172.4	-71	-69.3	0	0	0	109.2	I138 R188 E317 L321 D471	I138-Y313 HydrophobicContact CD1-CD2 4.13Å; I138-Y313 HydrophobicContact CD1-CE2 3.38Å; I138-Y313 HydrophobicContact CG1-CD2 4.47Å; I138-Y313 HydrophobicContact CG1-CE2 3.94Å; R188-Y313 HydrophobicContact CG-CE1 4.37Å; Y313-E317 WeakPolarHBondContact CA-OE2 3.28Å; Y313-E317 HydrophobicContact CD1-CB 4.27Å; Y313-E317 WeakPolarHBondContact CD1-OE2 3.3Å; Y313-L321 HydrophobicContact CD1-CD1 4.08Å; Y313-L321 HydrophobicContact CD2-CD1 4.29Å; Y313-L321 HydrophobicContact CE1-CD1 3.93Å; Y313-L321 HydrophobicContact CE2-CD1 4.11Å; Y313-L321 HydrophobicContact CG-CD1 4.28Å; Y313-D471 PolarHBondContact OH-OD1 3.28Å; Y313-D471 PolarHBondContact OH-OD2 3.21Å
314	R	65.7	Low	77.2	Confident	83 Å²	83	54.7 Å²	54.7	31%	0.313	29%	0.291	S	S	.	.			trans	-71.5	150.7	165	-60.8	-176.8	-174	-175.9	3.9	108.6	T316 E317 E318	R314-T316 PolarHBondContact O-N 3.45Å; R314-T316 VanDerWaalsContact O-N 3.17Å; R314-E317 HydrophobicContact CB-CG 4.15Å; R314-E317 PolarHBondContact N-OE2 3.29Å; R314-E317 WeakPolarHBondContact O-CB 3.14Å; R314-E317 PolarHBondContact O-N 2.88Å; R314-E317 VanDerWaalsContact O-N 3.09Å; R314-E318 PolarHBondContact O-N 3.12Å
315	P	69.5	Low	76.2	Confident	96 Å²	96	55.5 Å²	55.5	62%	0.623	30%	0.304	S	S	*	.	H	α-helix	trans	-55.3	-34.2	178.2	-27.9	36	0	0	0	113.6	E318 I319	P315-E318 PolarHBondContact O-N 2.9Å; P315-I319 WeakPolarHBondContact O-CD1 3.49Å; P315-I319 VanDerWaalsContact O-CG1 3.24Å; P315-I319 WeakPolarHBondContact O-CG1 3.42Å; P315-I319 PolarHBondContact O-N 3.36Å
316	T	62.1	Low	75.5	Confident	84 Å²	84	60.8 Å²	60.8	52%	0.515	32%	0.324	S	S	.	.	H	α-helix	trans	-61.3	-53.6	173.6	51.5	0	0	0	0	111.8	R314 E318 I319 D320	R314-T316 PolarHBondContact O-N 3.45Å; R314-T316 VanDerWaalsContact O-N 3.17Å; T316-E318 VanDerWaalsContact C-N 3.26Å; T316-E318 PolarHBondContact O-N 3.5Å; T316-I319 PolarHBondContact O-N 3.39Å; T316-I319 VanDerWaalsContact O-N 3.11Å; T316-D320 PolarHBondContact O-N 3.48Å
317	E	69.8	Low	74.7	Confident	28 Å²	28	60.3 Å²	60.3	13%	0.131	33%	0.334	C	S	.	.	H	α-helix	trans	-56.7	-39.7	175.7	-61.2	174.7	147.1	0	0	111.4	R188 Y313 R314 D320 L321	R188-E317 IonicContact CZ-OE1 3.37Å; R188-E317 IonicContact CZ-OE2 2.72Å; R188-E317 IonicContact NH2-OE1 3.19Å; R188-E317 PolarHBondContact NH2-OE1 2.93Å; R188-E317 IonicContact NH2-OE2 2.76Å; R188-E317 PolarHBondContact NH2-OE2 3.22Å; Y313-E317 WeakPolarHBondContact CA-OE2 3.28Å; Y313-E317 HydrophobicContact CD1-CB 4.27Å; Y313-E317 WeakPolarHBondContact CD1-OE2 3.3Å; R314-E317 HydrophobicContact CB-CG 4.15Å; R314-E317 PolarHBondContact N-OE2 3.29Å; R314-E317 WeakPolarHBondContact O-CB 3.14Å; R314-E317 PolarHBondContact O-N 2.88Å; R314-E317 VanDerWaalsContact O-N 3.09Å; E317-D320 PolarHBondContact O-N 3.28Å; E317-L321 WeakPolarHBondContact O-CB 3.44Å; E317-L321 WeakPolarHBondContact O-CD1 3.4Å; E317-L321 WeakPolarHBondContact O-CG 3.23Å; E317-L321 PolarHBondContact O-N 2.94Å
318	E	69.6	Low	74.1	Confident	78 Å²	78	57.7 Å²	57.7	36%	0.364	32%	0.32	S	S	.	.	H	α-helix	trans	-68.2	-34.4	179.3	-169.1	161.2	-140	0	0	112.7	G137 R314 P315 T316 R322	G137-E318 WeakPolarHBondContact CA-OE1 3.36Å; R314-E318 PolarHBondContact O-N 3.12Å; P315-E318 PolarHBondContact O-N 2.9Å; T316-E318 VanDerWaalsContact C-N 3.26Å; T316-E318 PolarHBondContact O-N 3.5Å; E318-R322 VanDerWaalsContact O-CB 3.3Å; E318-R322 WeakPolarHBondContact O-CB 3.45Å; E318-R322 PolarHBondContact O-N 3.27Å
319	I	67.1	Low	73.6	Confident	116 Å²	116	54.2 Å²	54.2	60%	0.595	30%	0.303	S	S	*	.	H	α-helix	trans	-68	-46.9	172.4	-67.5	160.8	0	0	0	110.5	P315 T316 L321 R322 S323	P315-I319 WeakPolarHBondContact O-CD1 3.49Å; P315-I319 VanDerWaalsContact O-CG1 3.24Å; P315-I319 WeakPolarHBondContact O-CG1 3.42Å; P315-I319 PolarHBondContact O-N 3.36Å; T316-I319 PolarHBondContact O-N 3.39Å; T316-I319 VanDerWaalsContact O-N 3.11Å; I319-L321 PolarHBondContact O-N 2.94Å; I319-R322 CarbonylContact O-C 3.48Å; I319-R322 PolarHBondContact O-N 2.71Å; I319-R322 VanDerWaalsContact O-N 3.14Å; I319-S323 PolarHBondContact O-N 2.95Å
320	D	68.4	Low	73.2	Confident	52 Å²	52	58.5 Å²	58.5	28%	0.278	32%	0.321	S	S	.	.	H	α-helix	trans	-60.3	-46.8	178.8	-66.7	-31	0	0	0	111.1	T316 E317 R322 S323 P535 H537	T316-D320 PolarHBondContact O-N 3.48Å; E317-D320 PolarHBondContact O-N 3.28Å; D320-R322 PolarHBondContact O-N 3.47Å; D320-S323 WeakPolarHBondContact O-CB 3.4Å; D320-S323 PolarHBondContact O-N 3.3Å; D320-S323 VanDerWaalsContact O-N 3.1Å; D320-S323 PolarHBondContact O-OG 3.37Å; D320-P535 HydrophobicContact CB-CB 4Å; D320-P535 HydrophobicContact CB-CG 4.17Å; D320-H537 IonicContact OD1-CE1 3.57Å; D320-H537 PolarHBondContact OD1-CE1 2.88Å; D320-H537 IonicContact OD1-ND1 3.57Å
321	L	70.6	Confident	73.1	Confident	12 Å²	12	62 Å²	62	6%	0.063	33%	0.333	C	S	.	.	H	α-helix	trans	-65.8	-22.4	178.3	-65.7	170.7	0	0	0	113.4	Y313 E317 I319 I324 E468	Y313-L321 HydrophobicContact CD1-CD1 4.08Å; Y313-L321 HydrophobicContact CD2-CD1 4.29Å; Y313-L321 HydrophobicContact CE1-CD1 3.93Å; Y313-L321 HydrophobicContact CE2-CD1 4.11Å; Y313-L321 HydrophobicContact CG-CD1 4.28Å; E317-L321 WeakPolarHBondContact O-CB 3.44Å; E317-L321 WeakPolarHBondContact O-CD1 3.4Å; E317-L321 WeakPolarHBondContact O-CG 3.23Å; E317-L321 PolarHBondContact O-N 2.94Å; I319-L321 PolarHBondContact O-N 2.94Å; L321-I324 HydrophobicContact CD2-CD1 4.48Å; L321-E468 HydrophobicContact CD2-CB 3.87Å; L321-E468 HydrophobicContact CD2-CG 3.88Å
322	R	71.5	Confident	73.1	Confident	129 Å²	129	57.7 Å²	57.7	49%	0.487	31%	0.305	S	S	.	.	H	α-helix	trans	-87.9	-22.1	173.8	-176.5	174.8	179	141.4	-0.8	113.2	E318 I319 D320 I324	E318-R322 VanDerWaalsContact O-CB 3.3Å; E318-R322 WeakPolarHBondContact O-CB 3.45Å; E318-R322 PolarHBondContact O-N 3.27Å; I319-R322 CarbonylContact O-C 3.48Å; I319-R322 PolarHBondContact O-N 2.71Å; I319-R322 VanDerWaalsContact O-N 3.14Å; D320-R322 PolarHBondContact O-N 3.47Å; R322-I324 PolarHBondContact O-N 3.2Å
323	S	70	Confident	73.6	Confident	46 Å²	46	57.5 Å²	57.5	32%	0.322	30%	0.303	S	S	.	.	H	α-helix	trans	-69.8	-19.7	175	79.8	0	0	0	0	113	I319 D320 G325 P535	I319-S323 PolarHBondContact O-N 2.95Å; D320-S323 WeakPolarHBondContact O-CB 3.4Å; D320-S323 PolarHBondContact O-N 3.3Å; D320-S323 VanDerWaalsContact O-N 3.1Å; D320-S323 PolarHBondContact O-OG 3.37Å; S323-G325 PolarHBondContact O-N 3.37Å; S323-P535 WeakPolarHBondContact OG-CA 3.34Å; S323-P535 WeakPolarHBondContact OG-CB 3.41Å
324	I	72.6	Confident	74.4	Confident	11 Å²	11	60.9 Å²	60.9	6%	0.056	32%	0.318	C	S	.	.	S	Bend	trans	-61.2	115.5	172.9	-55.3	174.8	0	0	0	108.9	L321 R322 W326 N328 I329 L332 I532	L321-I324 HydrophobicContact CD2-CD1 4.48Å; R322-I324 PolarHBondContact O-N 3.2Å; I324-W326 PolarHBondContact O-N 2.82Å; I324-N328 HydrophobicContact CG2-CB 4.48Å; I324-I329 HydrophobicContact CB-CD1 4.39Å; I324-I329 HydrophobicContact CB-CG1 4.26Å; I324-I329 HydrophobicContact CG2-CG1 3.83Å; I324-I329 WeakPolarHBondContact O-CD1 3.38Å; I324-L332 HydrophobicContact CG2-CD1 4.35Å; I324-I532 HydrophobicContact CD1-CG2 3.99Å
325	G	75.1	Confident	75.3	Confident	39 Å²	39	61.2 Å²	61.2	40%	0.402	32%	0.322	S	S	.	.			trans	-55.2	134.6	-175.8	0	0	0	0	0	113.8	S323 G327 N328 I329	S323-G325 PolarHBondContact O-N 3.37Å; G325-G327 VanDerWaalsContact C-N 3.29Å; G325-G327 PolarHBondContact O-N 2.66Å; G325-G327 VanDerWaalsContact O-N 3.14Å; G325-N328 WeakPolarHBondContact O-CA 3.39Å; G325-N328 WeakPolarHBondContact O-CB 3.48Å; G325-N328 PolarHBondContact O-N 3.45Å; G325-I329 PolarHBondContact O-N 3.05Å
326	W	77.9	Confident	76	Confident	113 Å²	113	56.7 Å²	56.7	43%	0.428	29%	0.293	S	S	.	.	H	α-helix	trans	-52.9	-38.2	-172.1	-61.2	103	0	0	0	114.8	V131 F135 I324 N328 I329 F330	V131-W326 HydrophobicContact CG1-CE3 3.96Å; V131-W326 HydrophobicContact CG1-CZ3 3.94Å; F135-W326 HydrophobicContact CB-CH2 3.84Å; F135-W326 HydrophobicContact CB-CZ3 4.1Å; F135-W326 AromaticContact CD2-CH2 3.79Å; F135-W326 HydrophobicContact CD2-CH2 3.79Å; F135-W326 HydrophobicContact CD2-CZ2 4.25Å; F135-W326 HydrophobicContact CG-CH2 4.3Å; I324-W326 PolarHBondContact O-N 2.82Å; W326-N328 VanDerWaalsContact C-N 3.28Å; W326-N328 PolarHBondContact O-N 2.94Å; W326-I329 HydrophobicContact CE3-CD1 4.08Å; W326-I329 HydrophobicContact CZ3-CD1 4.3Å; W326-I329 PolarHBondContact O-N 3.01Å; W326-F330 PolarHBondContact O-N 3.36Å
327	G	76.4	Confident	77	Confident	50 Å²	50	54.8 Å²	54.8	52%	0.515	28%	0.279	S	S	.	.	H	α-helix	trans	-62.1	-33.9	175.9	0	0	0	0	0	113.5	G325	G325-G327 VanDerWaalsContact C-N 3.29Å; G325-G327 PolarHBondContact O-N 2.66Å; G325-G327 VanDerWaalsContact O-N 3.14Å
328	N	80.9	Confident	77.7	Confident	67 Å²	67	61.4 Å²	61.4	36%	0.358	30%	0.303	S	S	.	.	H	α-helix	trans	-74.6	-38.2	176.3	-70.2	-23.6	0	0	0	111.5	I324 G325 W326 F330 Q331 L332	I324-N328 HydrophobicContact CG2-CB 4.48Å; G325-N328 WeakPolarHBondContact O-CA 3.39Å; G325-N328 WeakPolarHBondContact O-CB 3.48Å; G325-N328 PolarHBondContact O-N 3.45Å; W326-N328 VanDerWaalsContact C-N 3.28Å; W326-N328 PolarHBondContact O-N 2.94Å; N328-F330 PolarHBondContact O-N 2.99Å; N328-Q331 PolarHBondContact O-N 3.48Å; N328-Q331 VanDerWaalsContact O-N 3.16Å; N328-L332 WeakPolarHBondContact O-CB 3.45Å; N328-L332 VanDerWaalsContact O-CG 3.24Å; N328-L332 WeakPolarHBondContact O-CG 3.19Å; N328-L332 PolarHBondContact O-N 3.19Å
329	I	82	Confident	78.5	Confident	0 Å²	0	57.8 Å²	57.8	0%	0	29%	0.286	C	S	.	.	H	α-helix	trans	-56.4	-40.3	175.7	-62.6	179.5	0	0	0	111.1	P130 V131 R134 I324 G325 W326 P333 F472	P130-I329 HydrophobicContact CB-CG2 4.29Å; V131-I329 HydrophobicContact CG2-CG2 4.14Å; R134-I329 HydrophobicContact CB-CD1 4.25Å; R134-I329 HydrophobicContact CG-CD1 4.42Å; R134-I329 HydrophobicContact CG-CG2 4.45Å; I324-I329 HydrophobicContact CB-CD1 4.39Å; I324-I329 HydrophobicContact CB-CG1 4.26Å; I324-I329 HydrophobicContact CG2-CG1 3.83Å; I324-I329 WeakPolarHBondContact O-CD1 3.38Å; G325-I329 PolarHBondContact O-N 3.05Å; W326-I329 HydrophobicContact CE3-CD1 4.08Å; W326-I329 HydrophobicContact CZ3-CD1 4.3Å; W326-I329 PolarHBondContact O-N 3.01Å; I329-P333 WeakPolarHBondContact O-CD 3.48Å; I329-F472 HydrophobicContact CG2-CE1 4.33Å
330	F	80.9	Confident	79.5	Confident	92 Å²	92	53.5 Å²	53.5	40%	0.404	26%	0.263	S	S	.	.	H	α-helix	trans	-65.6	-39.7	177.8	-177.1	-96.1	0	0	0	113.4	L127 W326 N328 F334	L127-F330 HydrophobicContact CB-CE2 3.95Å; L127-F330 HydrophobicContact CD2-CE2 3.93Å; L127-F330 HydrophobicContact CD2-CZ 3.88Å; L127-F330 HydrophobicContact CG-CE2 4.4Å; W326-F330 PolarHBondContact O-N 3.36Å; N328-F330 PolarHBondContact O-N 2.99Å; F330-F334 HydrophobicContact CE1-CE2 4.45Å; F330-F334 WeakPolarHBondContact O-CD2 3.46Å
331	Q	82.3	Confident	80.5	Confident	89 Å²	89	52 Å²	52	42%	0.416	25%	0.253	S	S	.	.	H	α-helix	trans	-78.9	-27.3	-179.6	-63.4	-177.7	8.9	0	0	113.5	N328 F334 K335	N328-Q331 PolarHBondContact O-N 3.48Å; N328-Q331 VanDerWaalsContact O-N 3.16Å; Q331-F334 PolarHBondContact O-N 3.43Å; Q331-F334 VanDerWaalsContact O-N 3.16Å; Q331-K335 HydrophobicContact CB-CD 4.43Å; Q331-K335 PolarHBondContact O-N 3.14Å
332	L	81	Confident	81.3	Confident	4 Å²	4	51.5 Å²	51.5	2%	0.021	25%	0.25	C	S	.	.	H	α-helix	trans	-56.5	-42.8	-172.9	-86.5	164.8	0	0	0	114.7	I324 N328 F334 K335 H336 F472 I532	I324-L332 HydrophobicContact CG2-CD1 4.35Å; N328-L332 WeakPolarHBondContact O-CB 3.45Å; N328-L332 VanDerWaalsContact O-CG 3.24Å; N328-L332 WeakPolarHBondContact O-CG 3.19Å; N328-L332 PolarHBondContact O-N 3.19Å; L332-F334 PolarHBondContact O-N 2.86Å; L332-K335 PolarHBondContact O-N 3.13Å; L332-H336 PolarHBondContact O-N 3.33Å; L332-H336 PolarHBondContact O-ND1 3.16Å; L332-F472 HydrophobicContact CB-CE1 4.24Å; L332-F472 HydrophobicContact CB-CE2 4.44Å; L332-F472 HydrophobicContact CB-CZ 4.13Å; L332-F472 HydrophobicContact CD1-CE2 4.37Å; L332-F472 HydrophobicContact CD1-CZ 4.08Å; L332-I532 HydrophobicContact CD2-CG1 4.26Å
333	P	83.7	Confident	82.3	Confident	0 Å²	0	52.1 Å²	52.1	0%	0	25%	0.252	C	S	.	.	H	α-helix	trans	-57.8	-46	174.1	-19.9	25.6	0	0	0	112.9	L126 P130 I329 K335 H336 L337 F472 I476	L126-P333 HydrophobicContact CD1-CB 3.9Å; L126-P333 HydrophobicContact CG-CB 4.49Å; P130-P333 HydrophobicContact CB-CG 4.18Å; P130-P333 HydrophobicContact CG-CG 3.57Å; I329-P333 WeakPolarHBondContact O-CD 3.48Å; P333-K335 PolarHBondContact O-N 2.92Å; P333-H336 WeakPolarHBondContact O-CB 3.22Å; P333-H336 PolarHBondContact O-N 2.91Å; P333-H336 VanDerWaalsContact O-N 3.09Å; P333-L337 PolarHBondContact O-N 2.88Å; P333-F472 HydrophobicContact CG-CD1 3.97Å; P333-I476 HydrophobicContact CB-CD1 4.22Å; P333-I476 HydrophobicContact CB-CG1 4.43Å; P333-I476 WeakPolarHBondContact O-CD1 3.18Å
334	F	84.6	Confident	83.4	Confident	90 Å²	90	51.3 Å²	51.3	40%	0.395	25%	0.245	S	C	.	.	H	α-helix	trans	-65.3	-39.6	178.4	-61.4	-76.5	0	0	0	111.7	L126 L127 F330 Q331 L332 H336 L337	L126-F334 HydrophobicContact CD2-CD1 4.28Å; L126-F334 HydrophobicContact CD2-CE1 3.6Å; L126-F334 HydrophobicContact CD2-CZ 3.78Å; L126-F334 HydrophobicContact CG-CE1 4.5Å; L126-F334 HydrophobicContact CG-CZ 4.21Å; L127-F334 HydrophobicContact CD2-CE2 4.2Å; L127-F334 HydrophobicContact CD2-CZ 3.79Å; F330-F334 HydrophobicContact CE1-CE2 4.45Å; F330-F334 WeakPolarHBondContact O-CD2 3.46Å; Q331-F334 PolarHBondContact O-N 3.43Å; Q331-F334 VanDerWaalsContact O-N 3.16Å; L332-F334 PolarHBondContact O-N 2.86Å; F334-H336 VanDerWaalsContact C-N 3.28Å; F334-H336 PolarHBondContact O-N 3.47Å; F334-L337 HydrophobicContact CD1-CD1 4.42Å; F334-L337 WeakPolarHBondContact O-CB 3.22Å; F334-L337 PolarHBondContact O-N 3.46Å
335	K	85.6	Confident	84.3	Confident	89 Å²	89	50.9 Å²	50.9	39%	0.387	24%	0.242	S	C	.	.	H	α-helix	trans	-62.9	-32.4	172.2	-68.3	179.6	-177.5	175.1	0	111.9	Q331 L332 P333 R338 P530	Q331-K335 HydrophobicContact CB-CD 4.43Å; Q331-K335 PolarHBondContact O-N 3.14Å; L332-K335 PolarHBondContact O-N 3.13Å; P333-K335 PolarHBondContact O-N 2.92Å; K335-R338 WeakPolarHBondContact O-CB 3.15Å; K335-R338 PolarHBondContact O-N 2.92Å; K335-P530 HydrophobicContact CB-CB 3.96Å; K335-P530 HydrophobicContact CB-CG 4.06Å
336	H	83.9	Confident	85.2	Confident	2 Å²	2	49.6 Å²	49.6	1%	0.009	23%	0.227	C	C	.	.	H	α-helix	trans	-72.4	-23.2	175.3	-78.9	86.7	0	0	0	114.3	L332 P333 F334 R338 D339 R469 I476	L332-H336 PolarHBondContact O-N 3.33Å; L332-H336 PolarHBondContact O-ND1 3.16Å; P333-H336 WeakPolarHBondContact O-CB 3.22Å; P333-H336 PolarHBondContact O-N 2.91Å; P333-H336 VanDerWaalsContact O-N 3.09Å; F334-H336 VanDerWaalsContact C-N 3.28Å; F334-H336 PolarHBondContact O-N 3.47Å; H336-R338 PolarHBondContact O-N 3.46Å; H336-R338 VanDerWaalsContact O-N 3.12Å; H336-D339 WeakPolarHBondContact O-CB 3.48Å; H336-D339 PolarHBondContact O-N 3.46Å; H336-R469 WeakPolarHBondContact NE2-CD 3.25Å; H336-R469 PolarHBondContact NE2-NH1 3.38Å; H336-I476 HydrophobicContact CB-CD1 4.23Å
337	L	82.8	Confident	86	Confident	43 Å²	43	45.3 Å²	45.3	23%	0.225	21%	0.214	C	C	.	.	T	Hydrogen-bonded Turn	trans	-64.9	-10.8	170.3	-64.6	172.6	0	0	0	113.2	P333 F334 D339 L342 R343 I476	P333-L337 PolarHBondContact O-N 2.88Å; F334-L337 HydrophobicContact CD1-CD1 4.42Å; F334-L337 WeakPolarHBondContact O-CB 3.22Å; F334-L337 PolarHBondContact O-N 3.46Å; L337-D339 VanDerWaalsContact C-N 3.27Å; L337-L342 HydrophobicContact CD2-CD2 4.34Å; L337-R343 PolarHBondContact O-NE 3.43Å; L337-R343 PolarHBondContact O-NH2 3.17Å; L337-R343 VanDerWaalsContact O-NH2 3.16Å; L337-I476 HydrophobicContact CD2-CD1 4.25Å; L337-I476 HydrophobicContact CD2-CG2 3.74Å; L337-I476 HydrophobicContact CG-CD1 4.42Å
338	R	84.5	Confident	86.8	Confident	167 Å²	167	42.9 Å²	42.9	63%	0.63	19%	0.189	S	C	*	.	T	Hydrogen-bonded Turn	trans	-70	-21.6	169.7	-160.8	175.6	-74.3	-177.1	-3.8	112.6	K335 H336 Y340 R343	K335-R338 WeakPolarHBondContact O-CB 3.15Å; K335-R338 PolarHBondContact O-N 2.92Å; H336-R338 PolarHBondContact O-N 3.46Å; H336-R338 VanDerWaalsContact O-N 3.12Å; R338-Y340 PolarHBondContact O-N 3.1Å; R338-R343 PolarHBondContact O-NH2 3.24Å; R338-R343 VanDerWaalsContact O-NH2 3.13Å
339	D	86.5	Confident	87.5	Confident	2 Å²	2	39.7 Å²	39.7	1%	0.011	17%	0.172	C	C	.	.	S	Bend	trans	-66.4	128.8	175.1	-168.9	-16.5	0	0	0	110.8	H336 L337 R341 L342 R343 Y463 P527	H336-D339 WeakPolarHBondContact O-CB 3.48Å; H336-D339 PolarHBondContact O-N 3.46Å; L337-D339 VanDerWaalsContact C-N 3.27Å; D339-R341 VanDerWaalsContact C-N 3.27Å; D339-R341 PolarHBondContact O-N 2.97Å; D339-R341 WeakPolarHBondContact OD1-CB 3.3Å; D339-R341 WeakPolarHBondContact OD1-CG 3.39Å; D339-R341 PolarHBondContact OD1-N 3.28Å; D339-R341 IonicContact OD1-NE 3.48Å; D339-R341 PolarHBondContact OD1-NE 3.47Å; D339-R341 IonicContact OD2-CZ 3.23Å; D339-R341 VanDerWaalsContact OD2-CZ 3.3Å; D339-R341 IonicContact OD2-NE 3.46Å; D339-R341 PolarHBondContact OD2-NE 3.12Å; D339-R341 IonicContact OD2-NH2 3.88Å; D339-R341 PolarHBondContact OD2-NH2 3.43Å; D339-L342 HydrophobicContact CB-CB 4.41Å; D339-R343 PolarHBondContact O-N 3.36Å; D339-Y463 PolarHBondContact OD2-OH 3.19Å; D339-P527 WeakPolarHBondContact OD1-CB 3.34Å
340	Y	88.3	Confident	88.1	Confident	27 Å²	27	41.9 Å²	41.9	11%	0.106	18%	0.183	C	C	.	.	H	α-helix	trans	-66.9	-29.8	179.1	76.4	-98.8	0	0	0	112.2	R338 L344 R520 V521 V525 P527	R338-Y340 PolarHBondContact O-N 3.1Å; Y340-L344 HydrophobicContact CD2-CD1 4.23Å; Y340-L344 WeakPolarHBondContact O-CB 3.49Å; Y340-L344 VanDerWaalsContact O-CG 3.3Å; Y340-L344 WeakPolarHBondContact O-CG 3.3Å; Y340-L344 PolarHBondContact O-N 3.3Å; Y340-L344 VanDerWaalsContact O-N 3.11Å; Y340-R520 HydrophobicContact CD2-CB 4.3Å; Y340-R520 HydrophobicContact CE2-CB 3.67Å; Y340-V521 HydrophobicContact CE2-CG2 4.35Å; Y340-V525 HydrophobicContact CE1-CB 4.39Å; Y340-V525 HydrophobicContact CE1-CG1 4.19Å; Y340-V525 WeakPolarHBondContact CE1-O 3.47Å; Y340-V525 PolarHBondContact OH-O 2.63Å; Y340-P527 HydrophobicContact CD1-CB 4.29Å; Y340-P527 HydrophobicContact CE1-CB 3.93Å
341	R	89.4	Confident	88.8	Confident	21 Å²	21	37.5 Å²	37.5	8%	0.079	16%	0.164	C	C	.	.	H	α-helix	trans	-63.1	-53.4	-179.7	-63.4	177.9	-68.3	175.8	-2.2	109.8	D339 L344 L345 L462 M517 M529	D339-R341 VanDerWaalsContact C-N 3.27Å; D339-R341 PolarHBondContact O-N 2.97Å; D339-R341 WeakPolarHBondContact OD1-CB 3.3Å; D339-R341 WeakPolarHBondContact OD1-CG 3.39Å; D339-R341 PolarHBondContact OD1-N 3.28Å; D339-R341 IonicContact OD1-NE 3.48Å; D339-R341 PolarHBondContact OD1-NE 3.47Å; D339-R341 IonicContact OD2-CZ 3.23Å; D339-R341 VanDerWaalsContact OD2-CZ 3.3Å; D339-R341 IonicContact OD2-NE 3.46Å; D339-R341 PolarHBondContact OD2-NE 3.12Å; D339-R341 IonicContact OD2-NH2 3.88Å; D339-R341 PolarHBondContact OD2-NH2 3.43Å; R341-L344 PolarHBondContact O-N 3.26Å; R341-L345 WeakPolarHBondContact O-CG 3.33Å; R341-L345 PolarHBondContact O-N 3.26Å; R341-L345 VanDerWaalsContact O-N 3.15Å; R341-L462 PolarHBondContact NH1-O 2.69Å; R341-M517 HydrophobicContact CB-SD 4.5Å; R341-M529 PolarHBondContact NH2-SD 2.92Å; R341-M529 VanDerWaalsContact NH2-SD 3.44Å
342	L	88.4	Confident	89.4	Confident	1 Å²	1	33.2 Å²	33.2	1%	0.005	14%	0.144	C	C	.	.	H	α-helix	trans	-63.1	-45.3	-179.3	-165.3	59.4	0	0	0	111.5	L337 D339 L344 L345 C346 F349 V473 I476	L337-L342 HydrophobicContact CD2-CD2 4.34Å; D339-L342 HydrophobicContact CB-CB 4.41Å; L342-L344 VanDerWaalsContact C-N 3.33Å; L342-L344 PolarHBondContact O-N 3.01Å; L342-L345 PolarHBondContact O-N 2.86Å; L342-C346 PolarHBondContact O-N 3.5Å; L342-C346 PolarHBondContact O-SG 3.14Å; L342-F349 HydrophobicContact CD1-CE2 3.7Å; L342-F349 HydrophobicContact CD1-CZ 3.93Å; L342-V473 HydrophobicContact CD1-CG1 4.01Å; L342-I476 HydrophobicContact CD1-CG2 4.28Å; L342-I476 HydrophobicContact CD2-CB 4.28Å; L342-I476 HydrophobicContact CD2-CD1 3.63Å; L342-I476 HydrophobicContact CD2-CG2 3.89Å; L342-I476 HydrophobicContact CG-CG2 4.14Å
343	R	91.5	Very high	89.9	Confident	141 Å²	141	33.1 Å²	33.1	53%	0.532	14%	0.143	S	C	.	.	H	α-helix	trans	-59.1	-39.6	178.7	-168.2	-177.2	-52.8	159	12.8	113.5	L337 R338 D339 L345 C346	L337-R343 PolarHBondContact O-NE 3.43Å; L337-R343 PolarHBondContact O-NH2 3.17Å; L337-R343 VanDerWaalsContact O-NH2 3.16Å; R338-R343 PolarHBondContact O-NH2 3.24Å; R338-R343 VanDerWaalsContact O-NH2 3.13Å; D339-R343 PolarHBondContact O-N 3.36Å; R343-L345 VanDerWaalsContact C-N 3.33Å; R343-C346 PolarHBondContact O-N 3.22Å
344	L	92.6	Very high	90.4	Very high	30 Å²	30	33.5 Å²	33.5	16%	0.157	15%	0.145	C	C	.	.	H	α-helix	trans	-77.5	-18.6	177.9	-68.9	171.2	0	0	0	113	Y340 R341 L342 C513 V516 M517	Y340-L344 HydrophobicContact CD2-CD1 4.23Å; Y340-L344 WeakPolarHBondContact O-CB 3.49Å; Y340-L344 VanDerWaalsContact O-CG 3.3Å; Y340-L344 WeakPolarHBondContact O-CG 3.3Å; Y340-L344 PolarHBondContact O-N 3.3Å; Y340-L344 VanDerWaalsContact O-N 3.11Å; R341-L344 PolarHBondContact O-N 3.26Å; L342-L344 VanDerWaalsContact C-N 3.33Å; L342-L344 PolarHBondContact O-N 3.01Å; L344-C513 HydrophobicContact CB-CB 4.42Å; L344-C513 HydrophobicContact CD2-CB 4.05Å; L344-C513 VanDerWaalsContact O-CB 3.28Å; L344-C513 WeakPolarHBondContact O-CB 3.4Å; L344-V516 HydrophobicContact CD1-CG1 4.1Å; L344-M517 HydrophobicContact CB-CB 3.87Å; L344-M517 HydrophobicContact CB-CG 4.32Å; L344-M517 HydrophobicContact CD1-CB 3.82Å; L344-M517 HydrophobicContact CD1-CG 4.37Å
345	L	91.9	Very high	90.8	Very high	1 Å²	1	29.3 Å²	29.3	1%	0.005	13%	0.127	C	C	.	.	H	α-helix	trans	-83.7	-23.9	171.2	-74.1	163.1	0	0	0	113.2	R341 L342 R343 F348 F349 V458 L462 Y514 M517	R341-L345 WeakPolarHBondContact O-CG 3.33Å; R341-L345 PolarHBondContact O-N 3.26Å; R341-L345 VanDerWaalsContact O-N 3.15Å; L342-L345 PolarHBondContact O-N 2.86Å; R343-L345 VanDerWaalsContact C-N 3.33Å; L345-F348 WeakPolarHBondContact O-CA 3.38Å; L345-F348 WeakPolarHBondContact O-CB 3.22Å; L345-F348 PolarHBondContact O-N 3.46Å; L345-F349 HydrophobicContact CB-CD1 4.41Å; L345-F349 HydrophobicContact CB-CE1 3.75Å; L345-F349 HydrophobicContact CB-CE2 4.12Å; L345-F349 HydrophobicContact CB-CZ 3.59Å; L345-F349 HydrophobicContact CD1-CZ 4.42Å; L345-F349 WeakPolarHBondContact O-CG 3.28Å; L345-F349 PolarHBondContact O-N 3.5Å; L345-V458 HydrophobicContact CD2-CG1 4.37Å; L345-L462 HydrophobicContact CD1-CD1 3.91Å; L345-Y514 HydrophobicContact CD2-CD2 4.11Å; L345-M517 HydrophobicContact CD1-SD 3.87Å; L345-M517 HydrophobicContact CD2-SD 4.15Å; L345-M517 HydrophobicContact CG-SD 3.75Å
346	C	93.4	Very high	91.1	Very high	12 Å²	12	25.9 Å²	25.9	8%	0.081	11%	0.113	C	C	.	.	H	α-helix	trans	-49.8	-45.2	-179.5	-64.9	0	0	0	0	114.6	L342 R343 F348 F349 I350 W480	L342-C346 PolarHBondContact O-N 3.5Å; L342-C346 PolarHBondContact O-SG 3.14Å; R343-C346 PolarHBondContact O-N 3.22Å; C346-F348 PolarHBondContact O-N 3.42Å; C346-F349 WeakPolarHBondContact O-CB 3.48Å; C346-F349 PolarHBondContact O-N 3.14Å; C346-F349 VanDerWaalsContact O-N 3.17Å; C346-I350 WeakPolarHBondContact O-CG1 3.41Å; C346-I350 PolarHBondContact O-N 2.91Å; C346-W480 HydrophobicContact CB-CD2 4.4Å; C346-W480 HydrophobicContact CB-CZ2 4.5Å; C346-W480 PolarHBondContact SG-NE1 2.94Å
347	P	95.1	Very high	91.4	Very high	23 Å²	23	27.8 Å²	27.8	15%	0.149	12%	0.123	C	C	.	.	H	α-helix	trans	-62.7	-31.4	176.9	-23.2	35.5	0	0	0	113.2	Y351 L509 A510 C513	P347-Y351 WeakPolarHBondContact O-CB 3.43Å; P347-Y351 PolarHBondContact O-N 2.98Å; P347-L509 HydrophobicContact CB-CD2 4.44Å; P347-L509 HydrophobicContact CB-CG 4.27Å; P347-A510 HydrophobicContact CB-CB 4.23Å; P347-C513 HydrophobicContact CG-CB 4.3Å
348	F	94.3	Very high	91.8	Very high	0 Å²	0	26.1 Å²	26.1	0%	0	11%	0.114	C	C	.	.	H	α-helix	trans	-73.9	-36.4	175.8	-150.1	-68.1	0	0	0	111.5	L345 C346 I350 Y351 S352 L407 M408 N451 V455 A510	L345-F348 WeakPolarHBondContact O-CA 3.38Å; L345-F348 WeakPolarHBondContact O-CB 3.22Å; L345-F348 PolarHBondContact O-N 3.46Å; C346-F348 PolarHBondContact O-N 3.42Å; F348-I350 VanDerWaalsContact C-N 3.34Å; F348-Y351 PolarHBondContact O-N 3.09Å; F348-S352 WeakPolarHBondContact O-CB 3.43Å; F348-S352 PolarHBondContact O-N 3.39Å; F348-L407 HydrophobicContact CD1-CD2 4.48Å; F348-L407 HydrophobicContact CD2-CD2 3.88Å; F348-L407 HydrophobicContact CD2-CG 4.36Å; F348-L407 HydrophobicContact CE1-CD1 3.81Å; F348-L407 HydrophobicContact CE1-CD2 4.27Å; F348-L407 HydrophobicContact CE1-CG 4.05Å; F348-L407 HydrophobicContact CE2-CD1 4.32Å; F348-L407 HydrophobicContact CE2-CD2 3.66Å; F348-L407 HydrophobicContact CE2-CG 3.64Å; F348-L407 HydrophobicContact CG-CD2 4.31Å; F348-L407 HydrophobicContact CZ-CD1 3.68Å; F348-L407 HydrophobicContact CZ-CD2 3.88Å; F348-L407 HydrophobicContact CZ-CG 3.46Å; F348-L407 VanDerWaalsContact CZ-CG 3.46Å; F348-M408 HydrophobicContact CE2-CE 4.25Å; F348-N451 HydrophobicContact CE1-CB 4.08Å; F348-N451 HydrophobicContact CZ-CB 4.26Å; F348-V455 HydrophobicContact CD1-CG2 3.26Å; F348-V455 HydrophobicContact CE1-CG2 3.45Å; F348-V455 VanDerWaalsContact CE1-CG2 3.45Å; F348-V455 HydrophobicContact CG-CG2 4.28Å; F348-A510 HydrophobicContact CB-CB 4.05Å; F348-A510 HydrophobicContact CD2-CB 3.77Å; F348-A510 HydrophobicContact CG-CB 4.18Å
349	F	94.9	Very high	92.2	Very high	0 Å²	0	18.2 Å²	18.2	0%	0	8%	0.084	C	C	.	.	H	α-helix	trans	-60.8	-44.3	171.5	-55.9	-22.4	0	0	0	111.5	L342 L345 C346 S352 G353 V455 V459 Y477 W480 Q481	L342-F349 HydrophobicContact CD1-CE2 3.7Å; L342-F349 HydrophobicContact CD1-CZ 3.93Å; L345-F349 HydrophobicContact CB-CD1 4.41Å; L345-F349 HydrophobicContact CB-CE1 3.75Å; L345-F349 HydrophobicContact CB-CE2 4.12Å; L345-F349 HydrophobicContact CB-CZ 3.59Å; L345-F349 HydrophobicContact CD1-CZ 4.42Å; L345-F349 WeakPolarHBondContact O-CG 3.28Å; L345-F349 PolarHBondContact O-N 3.5Å; C346-F349 WeakPolarHBondContact O-CB 3.48Å; C346-F349 PolarHBondContact O-N 3.14Å; C346-F349 VanDerWaalsContact O-N 3.17Å; F349-S352 PolarHBondContact O-N 3.46Å; F349-G353 PolarHBondContact O-N 2.91Å; F349-V455 HydrophobicContact CD1-CG1 3.8Å; F349-V455 HydrophobicContact CE1-CG1 3.66Å; F349-V459 HydrophobicContact CE1-CG2 3.99Å; F349-V459 HydrophobicContact CZ-CG2 4.05Å; F349-Y477 HydrophobicContact CB-CD2 3.98Å; F349-Y477 HydrophobicContact CB-CE2 4.47Å; F349-Y477 AromaticContact CD1-CD2 3.28Å; F349-Y477 HydrophobicContact CD1-CD2 3.28Å; F349-Y477 AromaticContact CD1-CE2 3.78Å; F349-Y477 HydrophobicContact CD1-CE2 3.78Å; F349-Y477 HydrophobicContact CD1-CG 4.2Å; F349-Y477 HydrophobicContact CD2-CD2 4.18Å; F349-Y477 AromaticContact CE1-CD2 3.64Å; F349-Y477 HydrophobicContact CE1-CD2 3.64Å; F349-Y477 HydrophobicContact CE1-CE2 4.3Å; F349-Y477 HydrophobicContact CE1-CG 4.14Å; F349-Y477 HydrophobicContact CE2-CD2 4.49Å; F349-Y477 AromaticContact CG-CD2 3.57Å; F349-Y477 HydrophobicContact CG-CD2 3.57Å; F349-Y477 HydrophobicContact CG-CE2 4.31Å; F349-Y477 HydrophobicContact CG-CG 4.49Å; F349-Y477 HydrophobicContact CZ-CD2 4.24Å; F349-Y477 HydrophobicContact CZ-CG 4.4Å; F349-W480 HydrophobicContact CB-CB 3.7Å; F349-W480 HydrophobicContact CD2-CB 4.16Å; F349-W480 HydrophobicContact CD2-CG 4.36Å; F349-W480 HydrophobicContact CG-CB 4.47Å; F349-Q481 VanDerWaalsContact O-CG 3.28Å; F349-Q481 WeakPolarHBondContact O-CG 3.5Å
350	I	95.2	Very high	92.3	Very high	45 Å²	45	19.7 Å²	19.7	23%	0.231	9%	0.091	C	C	.	.	H	α-helix	trans	-59.5	-53.2	174.3	-66.8	167.6	0	0	0	109.7	C346 F348 S352 G353 L354 W480 A484	C346-I350 WeakPolarHBondContact O-CG1 3.41Å; C346-I350 PolarHBondContact O-N 2.91Å; F348-I350 VanDerWaalsContact C-N 3.34Å; I350-S352 VanDerWaalsContact C-N 3.29Å; I350-S352 PolarHBondContact O-N 2.87Å; I350-G353 PolarHBondContact O-N 3.02Å; I350-L354 HydrophobicContact CG2-CD1 4.09Å; I350-L354 HydrophobicContact CG2-CG 4.22Å; I350-L354 WeakPolarHBondContact O-CG 3.48Å; I350-L354 PolarHBondContact O-N 3.47Å; I350-W480 HydrophobicContact CD1-CE3 3.68Å; I350-W480 HydrophobicContact CD1-CZ3 3.83Å; I350-W480 HydrophobicContact CG1-CD2 4.47Å; I350-W480 HydrophobicContact CG1-CE3 3.74Å; I350-W480 HydrophobicContact CG1-CZ3 4.38Å; I350-A484 HydrophobicContact CB-CB 4.39Å; I350-A484 HydrophobicContact CG2-CB 3.98Å; I350-A484 WeakPolarHBondContact O-CB 3.44Å
351	Y	95.4	Very high	92.2	Very high	0 Å²	0	20.4 Å²	20.4	0%	0	10%	0.1	C	C	.	.	H	α-helix	trans	-54	-44.4	179.3	178.6	-101.9	0	0	0	112.5	P347 F348 G353 L354 E355 H414 L507	P347-Y351 WeakPolarHBondContact O-CB 3.43Å; P347-Y351 PolarHBondContact O-N 2.98Å; F348-Y351 PolarHBondContact O-N 3.09Å; Y351-G353 VanDerWaalsContact C-N 3.26Å; Y351-G353 PolarHBondContact O-N 3.41Å; Y351-L354 PolarHBondContact O-N 2.92Å; Y351-L354 VanDerWaalsContact O-N 3.07Å; Y351-E355 HydrophobicContact CD1-CG 4.3Å; Y351-E355 HydrophobicContact CE1-CB 4.17Å; Y351-E355 HydrophobicContact CE1-CG 3.96Å; Y351-E355 HydrophobicContact CE2-CB 4.42Å; Y351-E355 WeakPolarHBondContact O-CG 3.16Å; Y351-E355 PolarHBondContact O-N 2.95Å; Y351-H414 AromaticContact CE1-ND1 3.86Å; Y351-H414 AromaticContact CZ-ND1 3.92Å; Y351-H414 VanDerWaalsContact OH-CB 3.25Å; Y351-H414 WeakPolarHBondContact OH-CB 3.45Å; Y351-H414 PolarHBondContact OH-ND1 3.36Å; Y351-H414 VanDerWaalsContact OH-ND1 3.09Å; Y351-L507 HydrophobicContact CD1-CD1 4.04Å; Y351-L507 HydrophobicContact CD2-CB 3.88Å; Y351-L507 HydrophobicContact CD2-CD1 4.36Å; Y351-L507 HydrophobicContact CE1-CD1 3.68Å; Y351-L507 HydrophobicContact CE2-CB 3.62Å; Y351-L507 HydrophobicContact CE2-CD1 4.04Å; Y351-L507 HydrophobicContact CE2-CD2 4.34Å; Y351-L507 HydrophobicContact CE2-CG 4.21Å; Y351-L507 HydrophobicContact CG-CD1 4.37Å
352	S	93.8	Very high	92.1	Very high	0 Å²	0	20 Å²	20	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-63.9	-25.4	177.7	-177.3	0	0	0	0	114.2	F348 F349 I350 M356 K452 Q481	F348-S352 WeakPolarHBondContact O-CB 3.43Å; F348-S352 PolarHBondContact O-N 3.39Å; F349-S352 PolarHBondContact O-N 3.46Å; I350-S352 VanDerWaalsContact C-N 3.29Å; I350-S352 PolarHBondContact O-N 2.87Å; S352-M356 WeakPolarHBondContact O-CB 3.47Å; S352-K452 WeakPolarHBondContact OG-CD 3.36Å; S352-Q481 PolarHBondContact OG-NE2 3.4Å
353	G	92.8	Very high	92.2	Very high	1 Å²	1	19.9 Å²	19.9	1%	0.01	10%	0.102	C	C	.	.	H	α-helix	trans	-77.6	-42.1	168.6	0	0	0	0	0	112.4	F349 I350 Y351 L357	F349-G353 PolarHBondContact O-N 2.91Å; I350-G353 PolarHBondContact O-N 3.02Å; Y351-G353 VanDerWaalsContact C-N 3.26Å; Y351-G353 PolarHBondContact O-N 3.41Å; G353-L357 PolarHBondContact O-N 3.15Å
354	L	93.4	Very high	92.2	Very high	8 Å²	8	13.2 Å²	13.2	4%	0.042	8%	0.077	C	C	.	.	H	α-helix	trans	-62.7	-48.2	178.8	-62.3	-177.7	0	0	0	112.4	I350 Y351 M356 L357 F358 A484 V488 L503 T506	I350-L354 HydrophobicContact CG2-CD1 4.09Å; I350-L354 HydrophobicContact CG2-CG 4.22Å; I350-L354 WeakPolarHBondContact O-CG 3.48Å; I350-L354 PolarHBondContact O-N 3.47Å; Y351-L354 PolarHBondContact O-N 2.92Å; Y351-L354 VanDerWaalsContact O-N 3.07Å; L354-M356 PolarHBondContact O-N 3.49Å; L354-L357 PolarHBondContact O-N 2.91Å; L354-F358 WeakPolarHBondContact O-CB 3.47Å; L354-F358 PolarHBondContact O-N 3.41Å; L354-A484 HydrophobicContact CD2-CB 3.98Å; L354-A484 HydrophobicContact CG-CB 4.13Å; L354-V488 HydrophobicContact CD2-CG2 3.51Å; L354-L503 HydrophobicContact CB-CG 4.25Å; L354-T506 HydrophobicContact CD1-CG2 4.07Å
355	E	93.6	Very high	91.9	Very high	2 Å²	2	15.6 Å²	15.6	1%	0.009	9%	0.09	C	C	.	.	H	α-helix	trans	-64.8	-38.5	-178.2	58.1	113.6	175.1	0	0	112.8	Y351 F358 I359 H414 W444 S448	Y351-E355 HydrophobicContact CD1-CG 4.3Å; Y351-E355 HydrophobicContact CE1-CB 4.17Å; Y351-E355 HydrophobicContact CE1-CG 3.96Å; Y351-E355 HydrophobicContact CE2-CB 4.42Å; Y351-E355 WeakPolarHBondContact O-CG 3.16Å; Y351-E355 PolarHBondContact O-N 2.95Å; E355-F358 PolarHBondContact O-N 3.31Å; E355-I359 PolarHBondContact O-N 3.45Å; E355-H414 IonicContact OE1-CE1 2.98Å; E355-H414 IonicContact OE2-CE1 2.79Å; E355-H414 PolarHBondContact OE2-CE1 2.88Å; E355-W444 HydrophobicContact CB-CZ2 4.2Å; E355-S448 WeakPolarHBondContact OE2-CB 3.26Å; E355-S448 PolarHBondContact OE2-OG 2.92Å
356	M	90.7	Very high	91.7	Very high	18 Å²	18	16 Å²	16	9%	0.089	9%	0.092	C	C	.	.	H	α-helix	trans	-66.3	-44.4	177.8	178.8	173	171.4	0	0	112.6	Y78 F234 S352 L354 I359 I360 K452	Y78-M356 HydrophobicContact CE1-CE 4.29Å; Y78-M356 WeakPolarHBondContact OH-CE 3.04Å; F234-M356 HydrophobicContact CZ-CE 4.13Å; S352-M356 WeakPolarHBondContact O-CB 3.47Å; L354-M356 PolarHBondContact O-N 3.49Å; M356-I359 WeakPolarHBondContact O-CG2 2.87Å; M356-I360 HydrophobicContact CE-CD1 4.36Å; M356-I360 HydrophobicContact CG-CD1 4.16Å; M356-I360 WeakPolarHBondContact O-CD1 3.49Å; M356-I360 VanDerWaalsContact O-CG1 3.31Å; M356-I360 WeakPolarHBondContact O-CG1 3.45Å; M356-I360 PolarHBondContact O-N 3.18Å; M356-K452 PolarHBondContact SD-NZ 3.14Å
357	L	90.6	Very high	91.5	Very high	41 Å²	41	15.4 Å²	15.4	22%	0.215	9%	0.088	C	C	.	.	H	α-helix	trans	-71.2	-35.1	174.1	-99.8	-93.8	0	0	0	111.7	G353 L354 S361 I485 V488	G353-L357 PolarHBondContact O-N 3.15Å; L354-L357 PolarHBondContact O-N 2.91Å; L357-S361 PolarHBondContact O-N 2.97Å; L357-S361 PolarHBondContact O-OG 3.03Å; L357-I485 HydrophobicContact CD1-CG2 4.23Å; L357-I485 HydrophobicContact CD2-CB 4.48Å; L357-I485 HydrophobicContact CD2-CD1 4.29Å; L357-I485 HydrophobicContact CD2-CG1 3.82Å; L357-I485 HydrophobicContact CD2-CG2 4.09Å; L357-I485 HydrophobicContact CG-CB 4.31Å; L357-I485 HydrophobicContact CG-CG1 4Å; L357-I485 HydrophobicContact CG-CG2 4Å; L357-V488 HydrophobicContact CB-CB 4.3Å; L357-V488 HydrophobicContact CB-CG1 4.14Å; L357-V488 HydrophobicContact CB-CG2 4.16Å; L357-V488 HydrophobicContact CD1-CG1 4.29Å
358	F	91.9	Very high	91.2	Very high	8 Å²	8	14.3 Å²	14.3	4%	0.035	8%	0.081	C	C	.	.	I	π-helix	trans	-61.6	-45	176.5	175.5	-91.2	0	0	0	111.9	L354 E355 G362 F363 L421 W444 M496 L500 L503	L354-F358 WeakPolarHBondContact O-CB 3.47Å; L354-F358 PolarHBondContact O-N 3.41Å; E355-F358 PolarHBondContact O-N 3.31Å; F358-G362 CarbonylContact O-C 3.48Å; F358-G362 VanDerWaalsContact O-CA 3.25Å; F358-G362 WeakPolarHBondContact O-CA 3.18Å; F358-G362 PolarHBondContact O-N 3.11Å; F358-F363 HydrophobicContact CD1-CB 4.39Å; F358-F363 HydrophobicContact CE1-CB 3.95Å; F358-F363 HydrophobicContact CZ-CB 4.37Å; F358-F363 PolarHBondContact O-N 3.39Å; F358-L421 HydrophobicContact CE1-CD1 4.06Å; F358-L421 HydrophobicContact CZ-CD1 4.1Å; F358-W444 AromaticContact CD1-CH2 3.7Å; F358-W444 HydrophobicContact CD1-CH2 3.7Å; F358-W444 AromaticContact CD1-CZ2 3.61Å; F358-W444 HydrophobicContact CD1-CZ2 3.61Å; F358-W444 HydrophobicContact CD1-CZ3 4.49Å; F358-W444 AromaticContact CE1-CH2 3.64Å; F358-W444 HydrophobicContact CE1-CH2 3.64Å; F358-W444 HydrophobicContact CE1-CZ2 4.02Å; F358-W444 HydrophobicContact CE1-CZ3 4.07Å; F358-M496 HydrophobicContact CD2-CE 4.3Å; F358-M496 HydrophobicContact CE2-CE 3.39Å; F358-M496 HydrophobicContact CE2-SD 4.41Å; F358-M496 HydrophobicContact CZ-CE 3.86Å; F358-L500 HydrophobicContact CE1-CD2 4.48Å; F358-L500 HydrophobicContact CE2-CD2 3.72Å; F358-L500 HydrophobicContact CE2-CG 4.25Å; F358-L500 HydrophobicContact CZ-CD2 3.48Å; F358-L500 VanDerWaalsContact CZ-CD2 3.48Å; F358-L500 HydrophobicContact CZ-CG 4.4Å; F358-L503 HydrophobicContact CB-CD1 4.49Å; F358-L503 HydrophobicContact CB-CD2 3.65Å; F358-L503 HydrophobicContact CD1-CD2 4.17Å; F358-L503 HydrophobicContact CD2-CD1 4.06Å; F358-L503 HydrophobicContact CD2-CD2 3.98Å; F358-L503 HydrophobicContact CG-CD1 4.49Å; F358-L503 HydrophobicContact CG-CD2 3.66Å
359	I	92.1	Very high	91	Very high	1 Å²	1	14.3 Å²	14.3	1%	0.005	8%	0.081	C	C	.	.	I	π-helix	trans	-70.7	-43.8	-177.7	-162.7	63.5	0	0	0	112.1	E355 M356 F363 S364 Y384 M441 W444	E355-I359 PolarHBondContact O-N 3.45Å; M356-I359 WeakPolarHBondContact O-CG2 2.87Å; I359-F363 HydrophobicContact CD1-CB 3.97Å; I359-F363 HydrophobicContact CD1-CD1 3.9Å; I359-F363 HydrophobicContact CD1-CG 3.97Å; I359-S364 PolarHBondContact O-N 3.09Å; I359-S364 PolarHBondContact O-OG 3.27Å; I359-Y384 HydrophobicContact CG1-CD2 3.97Å; I359-Y384 HydrophobicContact CG1-CE2 4.02Å; I359-Y384 HydrophobicContact CG1-CG 4.4Å; I359-Y384 HydrophobicContact CG2-CE1 4.11Å; I359-Y384 HydrophobicContact CG2-CE2 3.95Å; I359-M441 HydrophobicContact CD1-CE 3.79Å; I359-M441 HydrophobicContact CD1-SD 3.47Å; I359-M441 WeakPolarHBondContact CD1-SD 3.48Å; I359-M441 HydrophobicContact CG1-CE 3.79Å; I359-M441 HydrophobicContact CG1-SD 4.17Å; I359-W444 HydrophobicContact CD1-CB 4.12Å; I359-W444 HydrophobicContact CD1-CD2 3.95Å; I359-W444 HydrophobicContact CD1-CG 3.6Å; I359-W444 HydrophobicContact CG1-CG 4.14Å
360	I	88.9	Confident	90.6	Very high	33 Å²	33	14.4 Å²	14.4	17%	0.169	8%	0.082	C	C	.	.	I	π-helix	trans	-67.4	-44	-178.9	-63.7	168.9	0	0	0	111.7	M82 F234 M356 S364	M82-I360 HydrophobicContact CE-CD1 4.21Å; M82-I360 HydrophobicContact CE-CG2 3.93Å; F234-I360 HydrophobicContact CE1-CD1 3.81Å; F234-I360 HydrophobicContact CE1-CG1 4.49Å; F234-I360 HydrophobicContact CZ-CD1 4.47Å; M356-I360 HydrophobicContact CE-CD1 4.36Å; M356-I360 HydrophobicContact CG-CD1 4.16Å; M356-I360 WeakPolarHBondContact O-CD1 3.49Å; M356-I360 VanDerWaalsContact O-CG1 3.31Å; M356-I360 WeakPolarHBondContact O-CG1 3.45Å; M356-I360 PolarHBondContact O-N 3.18Å; I360-S364 VanDerWaalsContact O-CB 3.32Å; I360-S364 WeakPolarHBondContact O-CB 3.37Å
361	S	86.9	Confident	90.2	Very high	42 Å²	42	12.9 Å²	12.9	29%	0.294	7%	0.074	S	C	.	.	I	π-helix	trans	-107.2	-59.1	-175.6	67.6	0	0	0	0	113.1	L357 L365	L357-S361 PolarHBondContact O-N 2.97Å; L357-S361 PolarHBondContact O-OG 3.03Å; S361-L365 WeakPolarHBondContact O-CB 3.25Å; S361-L365 VanDerWaalsContact O-CG 3.26Å; S361-L365 WeakPolarHBondContact O-CG 3.26Å; S361-L365 PolarHBondContact O-N 3.18Å
362	G	87.5	Confident	89.8	Confident	12 Å²	12	13.5 Å²	13.5	12%	0.124	8%	0.077	C	C	.	.	I	π-helix	trans	-60.1	-55.3	-172.7	0	0	0	0	0	113.6	F358 S366 M496	F358-G362 CarbonylContact O-C 3.48Å; F358-G362 VanDerWaalsContact O-CA 3.25Å; F358-G362 WeakPolarHBondContact O-CA 3.18Å; F358-G362 PolarHBondContact O-N 3.11Å; G362-S366 WeakPolarHBondContact O-CB 3.27Å; G362-S366 PolarHBondContact O-N 3.33Å; G362-S366 PolarHBondContact O-OG 3.11Å; G362-M496 WeakPolarHBondContact O-CE 3.44Å
363	F	90.2	Very high	89.5	Confident	0 Å²	0	13.5 Å²	13.5	0%	0	8%	0.078	C	C	.	.	I	π-helix	trans	-70.7	-51.9	-179.1	-178.5	-93.6	0	0	0	111.6	F358 I359 L365 S366 Y367 G368 L380 L421 L437 I440 M441	F358-F363 HydrophobicContact CD1-CB 4.39Å; F358-F363 HydrophobicContact CE1-CB 3.95Å; F358-F363 HydrophobicContact CZ-CB 4.37Å; F358-F363 PolarHBondContact O-N 3.39Å; I359-F363 HydrophobicContact CD1-CB 3.97Å; I359-F363 HydrophobicContact CD1-CD1 3.9Å; I359-F363 HydrophobicContact CD1-CG 3.97Å; F363-L365 VanDerWaalsContact C-N 3.35Å; F363-L365 PolarHBondContact O-N 3.45Å; F363-S366 PolarHBondContact O-N 2.97Å; F363-Y367 AromaticContact CD2-CD2 3.82Å; F363-Y367 HydrophobicContact CD2-CD2 3.82Å; F363-Y367 HydrophobicContact CD2-CG 4.05Å; F363-Y367 HydrophobicContact CE2-CD2 4.26Å; F363-Y367 HydrophobicContact CE2-CG 4.03Å; F363-Y367 WeakPolarHBondContact O-CA 3.23Å; F363-Y367 WeakPolarHBondContact O-CB 3.38Å; F363-Y367 PolarHBondContact O-N 3.45Å; F363-G368 PolarHBondContact O-N 3.48Å; F363-L380 HydrophobicContact CD1-CD2 4.12Å; F363-L380 HydrophobicContact CE1-CD1 4.38Å; F363-L380 HydrophobicContact CE1-CD2 3.96Å; F363-L380 HydrophobicContact CE1-CG 4.44Å; F363-L421 HydrophobicContact CD2-CD1 4Å; F363-L421 HydrophobicContact CD2-CD2 4.15Å; F363-L421 HydrophobicContact CE2-CD1 4.19Å; F363-L421 HydrophobicContact CE2-CD2 3.64Å; F363-L437 HydrophobicContact CE1-CD1 3.85Å; F363-L437 HydrophobicContact CE1-CG 4.48Å; F363-L437 HydrophobicContact CE2-CD1 4.24Å; F363-L437 HydrophobicContact CZ-CD1 3.37Å; F363-L437 HydrophobicContact CZ-CG 4.27Å; F363-I440 HydrophobicContact CE2-CG2 3.84Å; F363-I440 HydrophobicContact CZ-CB 4.47Å; F363-I440 HydrophobicContact CZ-CG2 3.74Å; F363-M441 HydrophobicContact CD1-CE 4.36Å; F363-M441 HydrophobicContact CD1-SD 3.42Å; F363-M441 WeakPolarHBondContact CD1-SD 3.45Å; F363-M441 HydrophobicContact CE1-CE 4.47Å; F363-M441 HydrophobicContact CE1-CG 3.86Å; F363-M441 HydrophobicContact CE1-SD 3.15Å; F363-M441 WeakPolarHBondContact CE1-SD 3.42Å; F363-M441 HydrophobicContact CG-SD 4.5Å; F363-M441 HydrophobicContact CZ-SD 4.07Å
364	S	90.3	Very high	89.3	Confident	0 Å²	0	14.5 Å²	14.5	0%	0	8%	0.082	C	C	.	.	I	π-helix	trans	-58.9	-44.5	-177.4	-63.7	0	0	0	0	111.8	I359 I360 G368 V369 L377	I359-S364 PolarHBondContact O-N 3.09Å; I359-S364 PolarHBondContact O-OG 3.27Å; I360-S364 VanDerWaalsContact O-CB 3.32Å; I360-S364 WeakPolarHBondContact O-CB 3.37Å; S364-G368 CarbonylContact O-C 3.58Å; S364-G368 WeakPolarHBondContact O-CA 3.44Å; S364-G368 PolarHBondContact O-N 3.45Å; S364-V369 PolarHBondContact O-N 3.19Å; S364-L377 WeakPolarHBondContact O-CD1 3.13Å
365	L	87.4	Confident	89	Confident	81 Å²	81	16.7 Å²	16.7	42%	0.424	9%	0.091	S	C	.	.	I	π-helix	trans	-78.8	-34.9	177.6	-57.5	174.4	0	0	0	113.6	I270 S361 F363 V369 L377	I270-L365 WeakPolarHBondContact CD1-O 3.37Å; S361-L365 WeakPolarHBondContact O-CB 3.25Å; S361-L365 VanDerWaalsContact O-CG 3.26Å; S361-L365 WeakPolarHBondContact O-CG 3.26Å; S361-L365 PolarHBondContact O-N 3.18Å; F363-L365 VanDerWaalsContact C-N 3.35Å; F363-L365 PolarHBondContact O-N 3.45Å; L365-V369 HydrophobicContact CD2-CG2 4.14Å; L365-L377 HydrophobicContact CD2-CD2 4.28Å
366	S	87.6	Confident	88.8	Confident	8 Å²	8	18.6 Å²	18.6	6%	0.056	10%	0.104	C	C	.	.	I	π-helix	trans	-89.4	-30.3	-173.7	-49.1	0	0	0	0	114.8	G263 G362 F363	G263-S366 PolarHBondContact N-O 3.06Å; G362-S366 WeakPolarHBondContact O-CB 3.27Å; G362-S366 PolarHBondContact O-N 3.33Å; G362-S366 PolarHBondContact O-OG 3.11Å; F363-S366 PolarHBondContact O-N 2.97Å
367	Y	88.9	Confident	88.8	Confident	0 Å²	0	18.3 Å²	18.3	0%	0	10%	0.102	C	C	.	.	I	π-helix	trans	-111.8	-49.1	-179.6	-66.6	-97	0	0	0	110.6	G263 A264 F363 C370 I371 L421 V426 M496	G263-Y367 VanDerWaalsContact CA-CZ 3.4Å; A264-Y367 WeakPolarHBondContact CA-OH 3.16Å; A264-Y367 PolarHBondContact N-OH 2.77Å; F363-Y367 AromaticContact CD2-CD2 3.82Å; F363-Y367 HydrophobicContact CD2-CD2 3.82Å; F363-Y367 HydrophobicContact CD2-CG 4.05Å; F363-Y367 HydrophobicContact CE2-CD2 4.26Å; F363-Y367 HydrophobicContact CE2-CG 4.03Å; F363-Y367 WeakPolarHBondContact O-CA 3.23Å; F363-Y367 WeakPolarHBondContact O-CB 3.38Å; F363-Y367 PolarHBondContact O-N 3.45Å; Y367-C370 PolarHBondContact O-N 3.3Å; Y367-I371 PolarHBondContact O-N 2.9Å; Y367-L421 HydrophobicContact CD1-CD2 4.42Å; Y367-L421 HydrophobicContact CE1-CD2 4.19Å; Y367-L421 PolarHBondContact OH-O 3.28Å; Y367-V426 HydrophobicContact CD1-CG2 3.83Å; Y367-V426 HydrophobicContact CE1-CG2 4.3Å; Y367-M496 HydrophobicContact CD2-CE 4.24Å; Y367-M496 HydrophobicContact CE2-CE 3.71Å; Y367-M496 HydrophobicContact CE2-CG 4.31Å
368	G	89.2	Confident	88.9	Confident	0 Å²	0	18.5 Å²	18.5	0%	0	10%	0.1	C	C	.	.	I	π-helix	trans	-57.1	-62.5	-178.4	0	0	0	0	0	112.9	F363 S364 C370 I371 L372	F363-G368 PolarHBondContact O-N 3.48Å; S364-G368 CarbonylContact O-C 3.58Å; S364-G368 WeakPolarHBondContact O-CA 3.44Å; S364-G368 PolarHBondContact O-N 3.45Å; G368-C370 PolarHBondContact O-N 2.84Å; G368-C370 VanDerWaalsContact O-N 3.11Å; G368-I371 PolarHBondContact O-N 3.19Å; G368-I371 VanDerWaalsContact O-N 3.11Å; G368-L372 WeakPolarHBondContact O-CB 3.17Å; G368-L372 PolarHBondContact O-N 3.26Å
369	V	88.9	Confident	88.9	Confident	1 Å²	1	20.7 Å²	20.7	1%	0.006	11%	0.112	C	C	.	.	H	α-helix	trans	-56.8	-28.7	179.4	173.4	0	0	0	0	112.6	L256 I270 F273 S364 L365 G373 I374 L377	L256-V369 WeakPolarHBondContact CD2-O 3.38Å; I270-V369 HydrophobicContact CD1-CB 4.05Å; I270-V369 HydrophobicContact CD1-CG1 3.8Å; F273-V369 HydrophobicContact CD2-CG1 4.46Å; F273-V369 HydrophobicContact CE2-CG1 3.56Å; F273-V369 HydrophobicContact CZ-CG1 4.25Å; S364-V369 PolarHBondContact O-N 3.19Å; L365-V369 HydrophobicContact CD2-CG2 4.14Å; V369-G373 WeakPolarHBondContact O-CA 3.32Å; V369-G373 PolarHBondContact O-N 3.35Å; V369-I374 HydrophobicContact CG1-CG1 3.88Å; V369-I374 HydrophobicContact CG2-CG1 3.92Å; V369-L377 HydrophobicContact CG2-CD1 3.87Å; V369-L377 HydrophobicContact CG2-CD2 3.79Å; V369-L377 HydrophobicContact CG2-CG 4.35Å
370	C	87.6	Confident	89	Confident	1 Å²	1	20.6 Å²	20.6	1%	0.007	11%	0.112	C	C	.	.	H	α-helix	trans	-72.7	-28.7	-179.9	-167.7	0	0	0	0	114.7	L256 C262 Y367 G368 V426 P428 N429	L256-C370 HydrophobicContact CD2-CB 4.44Å; C262-C370 HydrophobicContact CB-CB 3.49Å; C262-C370 VanDerWaalsContact CB-CB 3.49Å; C262-C370 WeakPolarHBondContact CB-SG 3.12Å; C262-C370 WeakPolarHBondContact SG-CB 3.47Å; C262-C370 CovalentContact SG-SG 2.01Å; C262-C370 PolarHBondContact SG-SG 2.63Å; Y367-C370 PolarHBondContact O-N 3.3Å; G368-C370 PolarHBondContact O-N 2.84Å; G368-C370 VanDerWaalsContact O-N 3.11Å; C370-V426 HydrophobicContact CB-CG1 4.36Å; C370-P428 WeakPolarHBondContact SG-CA 3.37Å; C370-N429 PolarHBondContact O-N 3.45Å
371	I	87.5	Confident	89.2	Confident	13 Å²	13	19.6 Å²	19.6	7%	0.067	11%	0.106	C	C	.	.	H	α-helix	trans	-98.6	-47.5	179.9	-66.1	157.4	0	0	0	110.6	Y367 G368 V426 L437	Y367-I371 PolarHBondContact O-N 2.9Å; G368-I371 PolarHBondContact O-N 3.19Å; G368-I371 VanDerWaalsContact O-N 3.11Å; I371-V426 HydrophobicContact CD1-CG1 3.74Å; I371-V426 HydrophobicContact CD1-CG2 4.26Å; I371-V426 HydrophobicContact CG1-CG1 3.6Å; I371-L437 HydrophobicContact CB-CD2 4.29Å; I371-L437 HydrophobicContact CD1-CB 4.45Å; I371-L437 HydrophobicContact CD1-CD1 4.01Å; I371-L437 HydrophobicContact CD1-CD2 4.21Å; I371-L437 HydrophobicContact CD1-CG 4.47Å; I371-L437 HydrophobicContact CG2-CD2 4.4Å
372	L	86.9	Confident	89.6	Confident	13 Å²	13	19 Å²	19	7%	0.068	10%	0.1	C	C	.	.	H	α-helix	trans	-92.1	-24.9	-174.8	-80	159.8	0	0	0	113.8	N252 G368 T376 L380 L434 L437	N252-L372 PolarHBondContact ND2-O 2.97Å; N252-L372 PolarHBondContact OD1-O 2.95Å; G368-L372 WeakPolarHBondContact O-CB 3.17Å; G368-L372 PolarHBondContact O-N 3.26Å; L372-T376 WeakPolarHBondContact CD2-OG1 3.26Å; L372-T376 PolarHBondContact O-OG1 3.32Å; L372-L380 HydrophobicContact CD1-CB 4.39Å; L372-L380 HydrophobicContact CD1-CD1 3.99Å; L372-L434 HydrophobicContact CD1-CD1 4.36Å; L372-L434 HydrophobicContact CD2-CD1 3.61Å; L372-L434 HydrophobicContact CG-CD1 4.04Å; L372-L437 HydrophobicContact CD1-CD2 3.67Å; L372-L437 HydrophobicContact CG-CD2 4.28Å
373	G	87	Confident	90	Very high	1 Å²	1	19.9 Å²	19.9	1%	0.01	10%	0.103	C	C	.	.			trans	71.7	172.7	-165.9	0	0	0	0	0	113.2	N252 V369 K375 L377	N252-G373 WeakPolarHBondContact OD1-CA 3.27Å; V369-G373 WeakPolarHBondContact O-CA 3.32Å; V369-G373 PolarHBondContact O-N 3.35Å; G373-K375 VanDerWaalsContact C-N 3.32Å; G373-K375 PolarHBondContact O-N 3.17Å; G373-L377 PolarHBondContact O-N 3.22Å
374	I	87.3	Confident	90.3	Very high	22 Å²	22	20.4 Å²	20.4	11%	0.113	11%	0.105	C	C	.	.	G	3₁₀ helix	trans	-67	-35.3	178.3	-67.2	-169.1	0	0	0	111.3	T90 M241 L249 F273 V277 V369 T376 L377	T90-I374 HydrophobicContact CG2-CG2 4.14Å; M241-I374 HydrophobicContact CE-CG2 3.67Å; L249-I374 HydrophobicContact CD1-CG2 4.14Å; L249-I374 HydrophobicContact CD2-CG2 4.05Å; F273-I374 HydrophobicContact CE1-CD1 3.93Å; F273-I374 HydrophobicContact CE2-CD1 4.36Å; F273-I374 HydrophobicContact CZ-CD1 3.38Å; F273-I374 HydrophobicContact CZ-CG1 3.89Å; V277-I374 HydrophobicContact CG1-CB 4.36Å; V277-I374 HydrophobicContact CG1-CD1 4.03Å; V277-I374 HydrophobicContact CG1-CG2 4.36Å; V369-I374 HydrophobicContact CG1-CG1 3.88Å; V369-I374 HydrophobicContact CG2-CG1 3.92Å; I374-T376 VanDerWaalsContact C-N 3.26Å; I374-T376 PolarHBondContact O-N 2.92Å; I374-T376 VanDerWaalsContact O-N 3.15Å; I374-L377 WeakPolarHBondContact O-CB 3.43Å; I374-L377 PolarHBondContact O-N 3.45Å; I374-L377 VanDerWaalsContact O-N 3.14Å
375	K	88.9	Confident	90.5	Very high	53 Å²	53	20.4 Å²	20.4	23%	0.23	11%	0.105	C	C	.	.	G	3₁₀ helix	trans	-57.4	-32.3	-175.7	-177.4	166.3	-178.6	163.1	0	114.3	H246 L249 G373 W378	H246-K375 PolarHBondContact CE1-O 2.94Å; H246-K375 PolarHBondContact ND1-O 3.38Å; H246-K375 VanDerWaalsContact O-CE 3.27Å; H246-K375 WeakPolarHBondContact O-CE 3.33Å; L249-K375 HydrophobicContact CB-CB 4.19Å; L249-K375 HydrophobicContact CB-CG 4.38Å; G373-K375 VanDerWaalsContact C-N 3.32Å; G373-K375 PolarHBondContact O-N 3.17Å; K375-W378 PolarHBondContact O-NE1 2.94Å
376	T	88.9	Confident	90.9	Very high	43 Å²	43	20.3 Å²	20.3	26%	0.264	10%	0.104	S	C	.	.	G	3₁₀ helix	trans	-116.1	13	178.1	55.3	0	0	0	0	113.7	L372 I374 W378 L379	L372-T376 WeakPolarHBondContact CD2-OG1 3.26Å; L372-T376 PolarHBondContact O-OG1 3.32Å; I374-T376 VanDerWaalsContact C-N 3.26Å; I374-T376 PolarHBondContact O-N 2.92Å; I374-T376 VanDerWaalsContact O-N 3.15Å; T376-W378 PolarHBondContact O-N 2.95Å; T376-L379 WeakPolarHBondContact O-CB 3.35Å; T376-L379 PolarHBondContact O-N 3.46Å; T376-L379 VanDerWaalsContact O-N 3.16Å
377	L	90	Very high	91.3	Very high	12 Å²	12	20.3 Å²	20.3	6%	0.063	10%	0.104	C	C	.	.	H	α-helix	trans	-58.4	-35.7	179.1	-172.5	63.8	0	0	0	113	S364 L365 V369 G373 I374 L379 L380	S364-L377 WeakPolarHBondContact O-CD1 3.13Å; L365-L377 HydrophobicContact CD2-CD2 4.28Å; V369-L377 HydrophobicContact CG2-CD1 3.87Å; V369-L377 HydrophobicContact CG2-CD2 3.79Å; V369-L377 HydrophobicContact CG2-CG 4.35Å; G373-L377 PolarHBondContact O-N 3.22Å; I374-L377 WeakPolarHBondContact O-CB 3.43Å; I374-L377 PolarHBondContact O-N 3.45Å; I374-L377 VanDerWaalsContact O-N 3.14Å; L377-L379 PolarHBondContact O-N 2.79Å; L377-L379 VanDerWaalsContact O-N 3.12Å; L377-L380 HydrophobicContact CD1-CD2 4.1Å; L377-L380 WeakPolarHBondContact O-CB 3.15Å; L377-L380 PolarHBondContact O-N 2.83Å
378	W	92.4	Very high	91.6	Very high	44 Å²	44	20.4 Å²	20.4	17%	0.167	11%	0.105	C	C	.	.	H	α-helix	trans	-52.1	-33.4	177.3	67	-90.6	0	0	0	113.5	E238 M241 R242 H246 K375 T376 L380 L382	E238-W378 HydrophobicContact CB-CB 4.2Å; E238-W378 HydrophobicContact CG-CB 4.34Å; E238-W378 WeakPolarHBondContact OE2-CA 3.37Å; E238-W378 WeakPolarHBondContact OE2-CB 3.43Å; M241-W378 HydrophobicContact CB-CB 4.39Å; M241-W378 HydrophobicContact CG-CB 4.01Å; R242-W378 HydrophobicContact CB-CD2 4.06Å; R242-W378 HydrophobicContact CB-CE3 4.13Å; R242-W378 HydrophobicContact CB-CG 4.3Å; R242-W378 VanDerWaalsContact CD-CE2 3.42Å; R242-W378 VanDerWaalsContact CD-CZ2 3.49Å; R242-W378 HydrophobicContact CG-CD2 4.22Å; R242-W378 HydrophobicContact CG-CE3 4.18Å; R242-W378 HydrophobicContact CG-CH2 4.39Å; R242-W378 HydrophobicContact CG-CZ2 4.43Å; R242-W378 HydrophobicContact CG-CZ3 4.25Å; H246-W378 AromaticContact ND1-NE1 3.82Å; K375-W378 PolarHBondContact O-NE1 2.94Å; T376-W378 PolarHBondContact O-N 2.95Å; W378-L380 PolarHBondContact O-N 3.48Å; W378-L382 HydrophobicContact CE3-CD1 4.27Å; W378-L382 HydrophobicContact CZ3-CD1 4.08Å; W378-L382 VanDerWaalsContact O-CB 3.23Å; W378-L382 WeakPolarHBondContact O-CB 3.22Å; W378-L382 PolarHBondContact O-N 2.79Å
379	L	92.9	Very high	91.9	Very high	54 Å²	54	20.9 Å²	20.9	28%	0.283	11%	0.108	S	C	.	.	H	α-helix	trans	-63.5	-34.9	179	179.8	63.5	0	0	0	111.3	T376 L377 V383	T376-L379 WeakPolarHBondContact O-CB 3.35Å; T376-L379 PolarHBondContact O-N 3.46Å; T376-L379 VanDerWaalsContact O-N 3.16Å; L377-L379 PolarHBondContact O-N 2.79Å; L377-L379 VanDerWaalsContact O-N 3.12Å; L379-V383 HydrophobicContact CD1-CG2 4.28Å; L379-V383 WeakPolarHBondContact O-CB 3.33Å; L379-V383 VanDerWaalsContact O-CG2 3.23Å; L379-V383 WeakPolarHBondContact O-CG2 3.22Å; L379-V383 PolarHBondContact O-N 3.31Å
380	L	93.6	Very high	92.2	Very high	0 Å²	0	25.1 Å²	25.1	0%	0	13%	0.134	C	C	.	.	H	α-helix	trans	-67.7	-48.6	-176.8	-162	73	0	0	0	110.9	F363 L372 L377 W378 V383 Y384 L437 L438 M441	F363-L380 HydrophobicContact CD1-CD2 4.12Å; F363-L380 HydrophobicContact CE1-CD1 4.38Å; F363-L380 HydrophobicContact CE1-CD2 3.96Å; F363-L380 HydrophobicContact CE1-CG 4.44Å; L372-L380 HydrophobicContact CD1-CB 4.39Å; L372-L380 HydrophobicContact CD1-CD1 3.99Å; L377-L380 HydrophobicContact CD1-CD2 4.1Å; L377-L380 WeakPolarHBondContact O-CB 3.15Å; L377-L380 PolarHBondContact O-N 2.83Å; W378-L380 PolarHBondContact O-N 3.48Å; L380-V383 PolarHBondContact O-N 3.4Å; L380-Y384 PolarHBondContact O-N 3.19Å; L380-Y384 VanDerWaalsContact O-N 3.11Å; L380-L437 HydrophobicContact CD1-CD2 3.72Å; L380-L437 HydrophobicContact CD1-CG 3.86Å; L380-L438 HydrophobicContact CD1-CD2 4.49Å; L380-M441 HydrophobicContact CD1-CG 3.38Å; L380-M441 HydrophobicContact CD1-SD 4.28Å; L380-M441 HydrophobicContact CD2-CE 4.4Å; L380-M441 HydrophobicContact CD2-SD 4.48Å; L380-M441 HydrophobicContact CG-CE 3.81Å; L380-M441 HydrophobicContact CG-CG 3.69Å; L380-M441 HydrophobicContact CG-SD 4.03Å; L380-M441 WeakPolarHBondContact O-CE 3.48Å
381	I	93.6	Very high	92.5	Very high	11 Å²	11	27.8 Å²	27.8	6%	0.056	15%	0.146	C	C	.	.	H	α-helix	trans	-71.9	-36.6	-180	-64.8	167.1	0	0	0	110.5	F234 E238 Y384 G385	F234-I381 HydrophobicContact CB-CG2 4.43Å; E238-I381 HydrophobicContact CG-CB 4.13Å; E238-I381 HydrophobicContact CG-CG2 4.03Å; E238-I381 WeakPolarHBondContact OE1-CB 3.16Å; E238-I381 WeakPolarHBondContact OE1-CD1 3.2Å; E238-I381 VanDerWaalsContact OE1-CG2 3.29Å; E238-I381 WeakPolarHBondContact OE1-CG2 3.29Å; I381-Y384 PolarHBondContact O-N 2.77Å; I381-G385 PolarHBondContact O-N 3.5Å
382	L	95.3	Very high	92.7	Very high	31 Å²	31	27.2 Å²	27.2	16%	0.162	14%	0.142	C	C	.	.	H	α-helix	trans	-60.5	-45.8	172.1	178.6	146	0	0	0	112.4	V235 W378 Y384 G385 L386	V235-L382 HydrophobicContact CG1-CD1 3.93Å; V235-L382 HydrophobicContact CG1-CG 4.06Å; W378-L382 HydrophobicContact CE3-CD1 4.27Å; W378-L382 HydrophobicContact CZ3-CD1 4.08Å; W378-L382 VanDerWaalsContact O-CB 3.23Å; W378-L382 WeakPolarHBondContact O-CB 3.22Å; W378-L382 PolarHBondContact O-N 2.79Å; L382-Y384 VanDerWaalsContact C-N 3.31Å; L382-Y384 PolarHBondContact O-N 3.47Å; L382-G385 PolarHBondContact O-N 3.49Å; L382-L386 HydrophobicContact CD2-CD1 3.68Å; L382-L386 HydrophobicContact CD2-CG 4.41Å; L382-L386 HydrophobicContact CG-CD1 4.41Å; L382-L386 WeakPolarHBondContact O-CG 3.34Å; L382-L386 PolarHBondContact O-N 2.97Å
383	V	96	Very high	92.9	Very high	30 Å²	30	31 Å²	31	18%	0.182	16%	0.162	C	C	.	.	H	α-helix	trans	-63.2	-38.6	177	165.4	0	0	0	0	111.1	L379 L380 S387 L438 M441 V442	L379-V383 HydrophobicContact CD1-CG2 4.28Å; L379-V383 WeakPolarHBondContact O-CB 3.33Å; L379-V383 VanDerWaalsContact O-CG2 3.23Å; L379-V383 WeakPolarHBondContact O-CG2 3.22Å; L379-V383 PolarHBondContact O-N 3.31Å; L380-V383 PolarHBondContact O-N 3.4Å; V383-S387 WeakPolarHBondContact O-CB 3.23Å; V383-S387 PolarHBondContact O-N 3.27Å; V383-L438 HydrophobicContact CG2-CD2 4.32Å; V383-M441 HydrophobicContact CG1-CB 4.28Å; V383-V442 HydrophobicContact CG1-CG2 3.61Å
384	Y	95.6	Very high	92.9	Very high	11 Å²	11	35 Å²	35	4%	0.043	18%	0.183	C	C	.	.	H	α-helix	trans	-64.6	-45.5	172.5	165	-97.8	0	0	0	112.6	F234 I359 L380 I381 L382 S387 C388 M441	F234-Y384 HydrophobicContact CD2-CE1 4.21Å; F234-Y384 HydrophobicContact CE2-CE1 4.27Å; F234-Y384 HydrophobicContact CG-CE1 4.4Å; I359-Y384 HydrophobicContact CG1-CD2 3.97Å; I359-Y384 HydrophobicContact CG1-CE2 4.02Å; I359-Y384 HydrophobicContact CG1-CG 4.4Å; I359-Y384 HydrophobicContact CG2-CE1 4.11Å; I359-Y384 HydrophobicContact CG2-CE2 3.95Å; L380-Y384 PolarHBondContact O-N 3.19Å; L380-Y384 VanDerWaalsContact O-N 3.11Å; I381-Y384 PolarHBondContact O-N 2.77Å; L382-Y384 VanDerWaalsContact C-N 3.31Å; L382-Y384 PolarHBondContact O-N 3.47Å; Y384-S387 WeakPolarHBondContact O-CB 3.34Å; Y384-S387 PolarHBondContact O-N 2.89Å; Y384-C388 WeakPolarHBondContact CE2-SG 3.38Å; Y384-C388 VanDerWaalsContact CZ-SG 3.51Å; Y384-C388 WeakPolarHBondContact O-CB 3.48Å; Y384-C388 PolarHBondContact O-N 3.48Å; Y384-C388 PolarHBondContact O-SG 3.48Å; Y384-C388 VanDerWaalsContact O-SG 3.35Å; Y384-M441 VanDerWaalsContact CB-CE 3.47Å; Y384-M441 HydrophobicContact CD2-CE 4.47Å; Y384-M441 HydrophobicContact CG-CE 4.1Å
385	G	95.3	Very high	92.7	Very high	0 Å²	0	34 Å²	34	0%	0	18%	0.178	C	C	.	.	H	α-helix	trans	-60.5	-46.2	177.4	0	0	0	0	0	113.1	I381 L382 C388 S389	I381-G385 PolarHBondContact O-N 3.5Å; L382-G385 PolarHBondContact O-N 3.49Å; G385-C388 PolarHBondContact O-N 3.27Å; G385-S389 WeakPolarHBondContact O-CB 3.34Å; G385-S389 PolarHBondContact O-N 3.24Å
386	L	96	Very high	92.5	Very high	78 Å²	78	34.1 Å²	34.1	41%	0.408	18%	0.181	S	C	.	.	H	α-helix	trans	-62.2	-45.4	174	-71.2	176.6	0	0	0	111.9	L232 V235 L382 S389 V390	L232-L386 HydrophobicContact CD2-CD2 4.29Å; V235-L386 HydrophobicContact CG2-CD2 3.87Å; V235-L386 HydrophobicContact CG2-CG 3.81Å; L382-L386 HydrophobicContact CD2-CD1 3.68Å; L382-L386 HydrophobicContact CD2-CG 4.41Å; L382-L386 HydrophobicContact CG-CD1 4.41Å; L382-L386 WeakPolarHBondContact O-CG 3.34Å; L382-L386 PolarHBondContact O-N 2.97Å; L386-S389 PolarHBondContact O-N 3.14Å; L386-V390 WeakPolarHBondContact O-CG2 3.22Å; L386-V390 PolarHBondContact O-N 3.26Å
387	S	96.2	Very high	92	Very high	9 Å²	9	33.8 Å²	33.8	6%	0.063	18%	0.18	C	C	.	.	H	α-helix	trans	-58	-49.9	176.4	178.3	0	0	0	0	111.4	V383 Y384 S389 V390 F391 V442	V383-S387 WeakPolarHBondContact O-CB 3.23Å; V383-S387 PolarHBondContact O-N 3.27Å; Y384-S387 WeakPolarHBondContact O-CB 3.34Å; Y384-S387 PolarHBondContact O-N 2.89Å; S387-S389 VanDerWaalsContact C-N 3.33Å; S387-S389 PolarHBondContact O-N 3.18Å; S387-V390 PolarHBondContact O-N 3.41Å; S387-F391 WeakPolarHBondContact O-CB 3.38Å; S387-F391 WeakPolarHBondContact O-CD2 3.45Å; S387-F391 PolarHBondContact O-N 3.49Å; S387-F391 WeakPolarHBondContact OG-CD2 3.28Å; S387-F391 VanDerWaalsContact OG-CE2 3.23Å; S387-F391 WeakPolarHBondContact OG-CE2 3.39Å; S387-V442 PolarHBondContact OG-O 3.37Å
388	C	95.4	Very high	91.5	Very high	1 Å²	1	34 Å²	34	1%	0.007	18%	0.181	C	C	.	.	H	α-helix	trans	-58.9	-42.3	176.5	-76.3	0	0	0	0	112.4	N231 Y384 G385 S392 G445	N231-C388 HydrophobicContact CB-CB 3.77Å; N231-C388 PolarHBondContact ND2-O 3.04Å; Y384-C388 WeakPolarHBondContact CE2-SG 3.38Å; Y384-C388 VanDerWaalsContact CZ-SG 3.51Å; Y384-C388 WeakPolarHBondContact O-CB 3.48Å; Y384-C388 PolarHBondContact O-N 3.48Å; Y384-C388 PolarHBondContact O-SG 3.48Å; Y384-C388 VanDerWaalsContact O-SG 3.35Å; G385-C388 PolarHBondContact O-N 3.27Å; C388-S392 WeakPolarHBondContact O-CB 3.43Å; C388-S392 PolarHBondContact O-N 3.29Å; C388-S392 PolarHBondContact O-OG 3.07Å; C388-S392 VanDerWaalsContact O-OG 3.09Å; C388-G445 WeakPolarHBondContact SG-CA 3.22Å; C388-G445 PolarHBondContact SG-O 3.16Å
389	S	95	Very high	90.9	Very high	11 Å²	11	35.7 Å²	35.7	8%	0.077	19%	0.193	C	C	.	.	H	α-helix	trans	-64.2	-49.2	178.1	-176.1	0	0	0	0	111.7	V228 L232 G385 L386 S387 S392	V228-S389 WeakPolarHBondContact CG2-O 3.49Å; V228-S389 WeakPolarHBondContact O-CB 3.47Å; V228-S389 PolarHBondContact O-OG 2.9Å; L232-S389 WeakPolarHBondContact CD2-OG 3.28Å; G385-S389 WeakPolarHBondContact O-CB 3.34Å; G385-S389 PolarHBondContact O-N 3.24Å; L386-S389 PolarHBondContact O-N 3.14Å; S387-S389 VanDerWaalsContact C-N 3.33Å; S387-S389 PolarHBondContact O-N 3.18Å; S389-S392 PolarHBondContact O-N 2.93Å
390	V	94.6	Very high	90.5	Very high	89 Å²	89	44.2 Å²	44.2	54%	0.539	22%	0.222	S	C	.	.	H	α-helix	trans	-63.4	-46.6	178.9	172.4	0	0	0	0	111.3	L386 S387 S392 L393	L386-V390 WeakPolarHBondContact O-CG2 3.22Å; L386-V390 PolarHBondContact O-N 3.26Å; S387-V390 PolarHBondContact O-N 3.41Å; V390-S392 VanDerWaalsContact C-N 3.35Å; V390-S392 PolarHBondContact O-N 2.85Å; V390-L393 WeakPolarHBondContact O-CB 3.42Å; V390-L393 PolarHBondContact O-N 2.93Å
391	F	94.2	Very high	90	Very high	58 Å²	58	48.2 Å²	48.2	25%	0.254	24%	0.243	S	C	.	.	H	α-helix	trans	-78	-14.6	-177.6	-64.4	-53	0	0	0	114.2	S387 L393 L394 V442 L446 A449	S387-F391 WeakPolarHBondContact O-CB 3.38Å; S387-F391 WeakPolarHBondContact O-CD2 3.45Å; S387-F391 PolarHBondContact O-N 3.49Å; S387-F391 WeakPolarHBondContact OG-CD2 3.28Å; S387-F391 VanDerWaalsContact OG-CE2 3.23Å; S387-F391 WeakPolarHBondContact OG-CE2 3.39Å; F391-L393 PolarHBondContact O-N 3Å; F391-L394 VanDerWaalsContact O-CB 3.24Å; F391-L394 WeakPolarHBondContact O-CB 3.43Å; F391-L394 PolarHBondContact O-N 3.2Å; F391-V442 HydrophobicContact CE2-CG1 3.87Å; F391-V442 HydrophobicContact CZ-CG1 4.3Å; F391-L446 HydrophobicContact CB-CB 4.49Å; F391-L446 HydrophobicContact CB-CD1 3.85Å; F391-L446 HydrophobicContact CD1-CD1 3.69Å; F391-L446 VanDerWaalsContact CD2-CA 3.47Å; F391-L446 HydrophobicContact CD2-CB 3.52Å; F391-L446 HydrophobicContact CD2-CD1 4.04Å; F391-L446 HydrophobicContact CD2-CG 4.35Å; F391-L446 HydrophobicContact CE1-CD1 4.21Å; F391-L446 HydrophobicContact CE2-CB 3.77Å; F391-L446 HydrophobicContact CG-CB 4Å; F391-L446 HydrophobicContact CG-CD1 3.6Å; F391-L446 HydrophobicContact CG-CG 4.39Å; F391-L446 HydrophobicContact CZ-CB 4.45Å; F391-A449 HydrophobicContact CB-CB 3.96Å
392	S	92	Very high	89.5	Confident	0 Å²	0	51 Å²	51	0%	0	26%	0.261	C	S	.	.	H	α-helix	trans	-61.2	-25.5	166	-80.9	0	0	0	0	112.2	N231 C388 S389 V390 L394 S395 T453	N231-S392 PolarHBondContact ND2-OG 3.07Å; C388-S392 WeakPolarHBondContact O-CB 3.43Å; C388-S392 PolarHBondContact O-N 3.29Å; C388-S392 PolarHBondContact O-OG 3.07Å; C388-S392 VanDerWaalsContact O-OG 3.09Å; S389-S392 PolarHBondContact O-N 2.93Å; V390-S392 VanDerWaalsContact C-N 3.35Å; V390-S392 PolarHBondContact O-N 2.85Å; S392-L394 VanDerWaalsContact C-N 3.29Å; S392-L394 PolarHBondContact O-N 3.35Å; S392-S395 WeakPolarHBondContact O-CB 3.42Å; S392-S395 PolarHBondContact O-N 3.18Å; S392-S395 PolarHBondContact O-OG 3.14Å; S392-T453 PolarHBondContact OG-OG1 3.43Å
393	L	90.1	Very high	88.8	Confident	92 Å²	92	51.7 Å²	51.7	48%	0.482	26%	0.262	S	S	.	.	G	3₁₀ helix	trans	-66.6	-28.7	169.9	-65.4	171.2	0	0	0	112.8	V228 V390 F391 S395 L396	V228-L393 HydrophobicContact CG2-CD2 3.68Å; V228-L393 HydrophobicContact CG2-CG 3.76Å; V390-L393 WeakPolarHBondContact O-CB 3.42Å; V390-L393 PolarHBondContact O-N 2.93Å; F391-L393 PolarHBondContact O-N 3Å; L393-S395 PolarHBondContact O-N 3.13Å; L393-L396 HydrophobicContact CD2-CD1 4.25Å; L393-L396 VanDerWaalsContact O-CB 3.27Å; L393-L396 WeakPolarHBondContact O-CB 3.29Å; L393-L396 WeakPolarHBondContact O-CG 3.46Å; L393-L396 PolarHBondContact O-N 3.04Å
394	L	88.2	Confident	88.2	Confident	87 Å²	87	55.5 Å²	55.5	46%	0.455	27%	0.273	S	S	.	.	G	3₁₀ helix	trans	-65.6	-21.6	177.4	-172	59.4	0	0	0	111.9	F391 S392 L396 S397 L446 L450	F391-L394 VanDerWaalsContact O-CB 3.24Å; F391-L394 WeakPolarHBondContact O-CB 3.43Å; F391-L394 PolarHBondContact O-N 3.2Å; S392-L394 VanDerWaalsContact C-N 3.29Å; S392-L394 PolarHBondContact O-N 3.35Å; L394-L396 PolarHBondContact O-N 2.99Å; L394-S397 WeakPolarHBondContact O-CB 3.35Å; L394-S397 PolarHBondContact O-N 3.49Å; L394-S397 PolarHBondContact O-OG 3.29Å; L394-L446 HydrophobicContact CD2-CD1 3.84Å; L394-L450 HydrophobicContact CB-CD2 4.31Å; L394-L450 HydrophobicContact CD2-CD2 4.19Å; L394-L450 HydrophobicContact CG-CD2 4.17Å
395	S	82.2	Confident	87.7	Confident	0 Å²	0	57.3 Å²	57.3	0%	0	29%	0.285	C	S	.	.	G	3₁₀ helix	trans	-63.9	-19.5	171.5	72.2	0	0	0	0	113.5	S224 S392 L393 S397 L398 T453	S224-S395 WeakPolarHBondContact CB-OG 3.21Å; S224-S395 PolarHBondContact OG-OG 3.42Å; S392-S395 WeakPolarHBondContact O-CB 3.42Å; S392-S395 PolarHBondContact O-N 3.18Å; S392-S395 PolarHBondContact O-OG 3.14Å; L393-S395 PolarHBondContact O-N 3.13Å; S395-S397 PolarHBondContact O-N 2.96Å; S395-S397 VanDerWaalsContact O-N 3.1Å; S395-L398 WeakPolarHBondContact O-CB 3.1Å; S395-L398 WeakPolarHBondContact O-CD1 3.14Å; S395-L398 PolarHBondContact O-N 2.66Å; S395-T453 VanDerWaalsContact OG-CG2 3.31Å; S395-T453 WeakPolarHBondContact OG-CG2 3.4Å
396	L	85.4	Confident	87.2	Confident	56 Å²	56	57.7 Å²	57.7	29%	0.293	29%	0.287	S	S	.	.	G	3₁₀ helix	trans	-62.8	-15.7	170.1	-63.6	171.2	0	0	0	112.5	T221 S224 L393 L394 L398 L399	T221-L396 HydrophobicContact CG2-CD2 4.5Å; S224-L396 WeakPolarHBondContact OG-CD2 3.36Å; L393-L396 HydrophobicContact CD2-CD1 4.25Å; L393-L396 VanDerWaalsContact O-CB 3.27Å; L393-L396 WeakPolarHBondContact O-CB 3.29Å; L393-L396 WeakPolarHBondContact O-CG 3.46Å; L393-L396 PolarHBondContact O-N 3.04Å; L394-L396 PolarHBondContact O-N 2.99Å; L396-L398 PolarHBondContact O-N 2.93Å; L396-L399 HydrophobicContact CD2-CD1 4.4Å; L396-L399 VanDerWaalsContact O-CB 3.28Å; L396-L399 WeakPolarHBondContact O-CB 3.47Å; L396-L399 VanDerWaalsContact O-CG 3.3Å; L396-L399 WeakPolarHBondContact O-CG 3.38Å; L396-L399 PolarHBondContact O-N 3Å
397	S	78.6	Confident	86.8	Confident	35 Å²	35	54 Å²	54	25%	0.245	27%	0.268	C	S	.	.	G	3₁₀ helix	trans	-61.9	-20.7	170.8	67	0	0	0	0	113.5	L394 S395 L399 R400 L401	L394-S397 WeakPolarHBondContact O-CB 3.35Å; L394-S397 PolarHBondContact O-N 3.49Å; L394-S397 PolarHBondContact O-OG 3.29Å; S395-S397 PolarHBondContact O-N 2.96Å; S395-S397 VanDerWaalsContact O-N 3.1Å; S397-L399 PolarHBondContact O-N 3.35Å; S397-L399 VanDerWaalsContact O-N 3.12Å; S397-R400 PolarHBondContact O-N 3.37Å; S397-L401 WeakPolarHBondContact O-CB 3.38Å; S397-L401 PolarHBondContact O-N 3.12Å
398	L	78.6	Confident	86.6	Confident	16 Å²	16	55.2 Å²	55.2	8%	0.084	27%	0.273	C	S	.	.	G	3₁₀ helix	trans	-59.6	-17.1	169.7	-81.6	105.7	0	0	0	113.5	I220 S395 L396 R400 R403 C406 T457	I220-L398 HydrophobicContact CD1-CB 4.08Å; I220-L398 HydrophobicContact CG1-CB 4.38Å; I220-L398 HydrophobicContact CG2-CB 4.17Å; S395-L398 WeakPolarHBondContact O-CB 3.1Å; S395-L398 WeakPolarHBondContact O-CD1 3.14Å; S395-L398 PolarHBondContact O-N 2.66Å; L396-L398 PolarHBondContact O-N 2.93Å; L398-R400 PolarHBondContact O-N 2.9Å; L398-R403 HydrophobicContact CD2-CG 4.38Å; L398-C406 HydrophobicContact CD1-CB 3.41Å; L398-C406 VanDerWaalsContact CD1-CB 3.41Å; L398-C406 VanDerWaalsContact CD1-SG 3.54Å; L398-C406 HydrophobicContact CD2-CB 4.42Å; L398-C406 HydrophobicContact CG-CB 3.95Å; L398-T457 HydrophobicContact CD2-CG2 4.26Å
399	L	81.2	Confident	86.4	Confident	80 Å²	80	56.5 Å²	56.5	42%	0.419	29%	0.287	S	S	.	.	G	3₁₀ helix	trans	-69.5	-18.6	172.5	-62.7	173.1	0	0	0	112.9	I220 L396 S397	I220-L399 HydrophobicContact CB-CD2 3.99Å; I220-L399 HydrophobicContact CD1-CD2 3.89Å; I220-L399 HydrophobicContact CG2-CD2 3.96Å; I220-L399 HydrophobicContact CG2-CG 4.01Å; L396-L399 HydrophobicContact CD2-CD1 4.4Å; L396-L399 VanDerWaalsContact O-CB 3.28Å; L396-L399 WeakPolarHBondContact O-CB 3.47Å; L396-L399 VanDerWaalsContact O-CG 3.3Å; L396-L399 WeakPolarHBondContact O-CG 3.38Å; L396-L399 PolarHBondContact O-N 3Å; S397-L399 PolarHBondContact O-N 3.35Å; S397-L399 VanDerWaalsContact O-N 3.12Å
400	R	83.1	Confident	86.3	Confident	234 Å²	234	56 Å²	56	88%	0.883	28%	0.283	S	S	*	.	T	Hydrogen-bonded Turn	trans	-122.9	-26.1	-178.1	-60.7	-175.7	-176.2	178.3	1.4	113.4	S397 L398	S397-R400 PolarHBondContact O-N 3.37Å; L398-R400 PolarHBondContact O-N 2.9Å
401	L	82.6	Confident	86.2	Confident	84 Å²	84	51.9 Å²	51.9	44%	0.44	26%	0.258	S	S	.	.	S	Bend	trans	-104.7	149	-175.8	-61.5	178.6	0	0	0	111.1	S397 V405	S397-L401 WeakPolarHBondContact O-CB 3.38Å; S397-L401 PolarHBondContact O-N 3.12Å; L401-V405 HydrophobicContact CD1-CG1 4.17Å
402	P	83.1	Confident	86.3	Confident	70 Å²	70	52 Å²	52	46%	0.455	27%	0.27	S	S	.	.			trans	-65.2	143.2	177.2	27.1	-33.1	0	0	0	111.1	W404 V405	P402-W404 PolarHBondContact O-N 2.86Å; P402-V405 HydrophobicContact CG-CG2 3.82Å; P402-V405 WeakPolarHBondContact O-CB 3.38Å; P402-V405 PolarHBondContact O-N 3.19Å
403	R	82.2	Confident	86.4	Confident	44 Å²	44	53.8 Å²	53.8	17%	0.166	28%	0.281	C	S	.	.	T	Hydrogen-bonded Turn	trans	-44.2	-38.8	-171.3	-175.6	172.4	66.3	-155.6	-8	115.3	L398 V405 V458 E518	L398-R403 HydrophobicContact CD2-CG 4.38Å; R403-V405 VanDerWaalsContact C-N 3.3Å; R403-V405 PolarHBondContact O-N 3.28Å; R403-V458 HydrophobicContact CG-CG2 3.65Å; R403-E518 IonicContact CZ-OE1 2.36Å; R403-E518 IonicContact CZ-OE2 2.7Å; R403-E518 IonicContact NE-OE1 3.51Å; R403-E518 PolarHBondContact NE-OE1 3.05Å; R403-E518 IonicContact NE-OE2 3.5Å; R403-E518 VanDerWaalsContact NH2-CD 3.33Å; R403-E518 IonicContact NH2-OE1 3.42Å; R403-E518 PolarHBondContact NH2-OE1 3.25Å; R403-E518 IonicContact NH2-OE2 3.65Å; R403-E518 PolarHBondContact NH2-OE2 2.93Å
404	W	82.6	Confident	86.7	Confident	111 Å²	111	49.4 Å²	49.4	42%	0.42	26%	0.258	S	S	.	.	H	α-helix	trans	-67.3	-24.7	-176.8	69.5	-94.6	0	0	0	114.7	P402 M408 Y514 W515 E518	P402-W404 PolarHBondContact O-N 2.86Å; W404-M408 HydrophobicContact CE3-CB 4.32Å; W404-M408 HydrophobicContact CE3-CG 4.23Å; W404-M408 WeakPolarHBondContact O-CB 3.45Å; W404-M408 WeakPolarHBondContact O-CG 3.25Å; W404-M408 PolarHBondContact O-N 3.36Å; W404-Y514 VanDerWaalsContact CA-OH 3.31Å; W404-Y514 WeakPolarHBondContact CA-OH 3.39Å; W404-Y514 HydrophobicContact CB-CE1 4.04Å; W404-W515 HydrophobicContact CE3-CZ3 4.47Å; W404-E518 HydrophobicContact CB-CG 4.28Å
405	V	85.8	Confident	87	Confident	48 Å²	48	46.1 Å²	46.1	29%	0.291	25%	0.245	S	C	.	.	H	α-helix	trans	-67	-42.1	-174	173.5	0	0	0	0	111.9	L401 P402 R403 G409	L401-V405 HydrophobicContact CD1-CG1 4.17Å; P402-V405 HydrophobicContact CG-CG2 3.82Å; P402-V405 WeakPolarHBondContact O-CB 3.38Å; P402-V405 PolarHBondContact O-N 3.19Å; R403-V405 VanDerWaalsContact C-N 3.3Å; R403-V405 PolarHBondContact O-N 3.28Å; V405-G409 WeakPolarHBondContact O-CA 3.3Å; V405-G409 PolarHBondContact O-N 3.33Å
406	C	84.8	Confident	87.7	Confident	8 Å²	8	50.8 Å²	50.8	5%	0.054	27%	0.273	C	S	.	.	H	α-helix	trans	-63.3	-48.8	179.1	-177.6	0	0	0	0	111.3	L398 G409 G410 L450	L398-C406 HydrophobicContact CD1-CB 3.41Å; L398-C406 VanDerWaalsContact CD1-CB 3.41Å; L398-C406 VanDerWaalsContact CD1-SG 3.54Å; L398-C406 HydrophobicContact CD2-CB 4.42Å; L398-C406 HydrophobicContact CG-CB 3.95Å; C406-G409 PolarHBondContact O-N 3Å; C406-G410 PolarHBondContact O-N 3.07Å; C406-L450 VanDerWaalsContact SG-CD2 3.56Å; C406-L450 PolarHBondContact SG-O 2.86Å
407	L	87.1	Confident	88.1	Confident	1 Å²	1	48.6 Å²	48.6	1%	0.005	26%	0.262	C	S	.	.	H	α-helix	trans	-72.6	-38.2	-173.8	-152.2	75.5	0	0	0	112.4	F348 A411 N451 V455 Y514	F348-L407 HydrophobicContact CD1-CD2 4.48Å; F348-L407 HydrophobicContact CD2-CD2 3.88Å; F348-L407 HydrophobicContact CD2-CG 4.36Å; F348-L407 HydrophobicContact CE1-CD1 3.81Å; F348-L407 HydrophobicContact CE1-CD2 4.27Å; F348-L407 HydrophobicContact CE1-CG 4.05Å; F348-L407 HydrophobicContact CE2-CD1 4.32Å; F348-L407 HydrophobicContact CE2-CD2 3.66Å; F348-L407 HydrophobicContact CE2-CG 3.64Å; F348-L407 HydrophobicContact CG-CD2 4.31Å; F348-L407 HydrophobicContact CZ-CD1 3.68Å; F348-L407 HydrophobicContact CZ-CD2 3.88Å; F348-L407 HydrophobicContact CZ-CG 3.46Å; F348-L407 VanDerWaalsContact CZ-CG 3.46Å; L407-A411 VanDerWaalsContact O-CB 3.31Å; L407-A411 WeakPolarHBondContact O-CB 3.02Å; L407-A411 PolarHBondContact O-N 3.38Å; L407-N451 PolarHBondContact O-OD1 2.7Å; L407-V455 HydrophobicContact CD1-CG2 3.87Å; L407-Y514 HydrophobicContact CB-CD1 4.49Å; L407-Y514 HydrophobicContact CB-CE1 3.86Å; L407-Y514 HydrophobicContact CD2-CD1 3.85Å; L407-Y514 HydrophobicContact CD2-CD2 3.65Å; L407-Y514 HydrophobicContact CD2-CE1 3.76Å; L407-Y514 HydrophobicContact CD2-CE2 3.59Å; L407-Y514 HydrophobicContact CD2-CG 3.79Å; L407-Y514 HydrophobicContact CG-CE1 4.38Å
408	M	91.1	Very high	88.9	Confident	34 Å²	34	46.9 Å²	46.9	17%	0.167	25%	0.25	C	S	.	.	H	α-helix	trans	-75.8	-29	174.3	-61.8	-68.9	77.8	0	0	112.5	F348 W404 A411 A412 C511 Y514	F348-M408 HydrophobicContact CE2-CE 4.25Å; W404-M408 HydrophobicContact CE3-CB 4.32Å; W404-M408 HydrophobicContact CE3-CG 4.23Å; W404-M408 WeakPolarHBondContact O-CB 3.45Å; W404-M408 WeakPolarHBondContact O-CG 3.25Å; W404-M408 PolarHBondContact O-N 3.36Å; M408-A411 HydrophobicContact CE-CB 4.05Å; M408-A412 VanDerWaalsContact O-CB 3.27Å; M408-A412 WeakPolarHBondContact O-CB 2.99Å; M408-A412 PolarHBondContact O-N 2.93Å; M408-C511 HydrophobicContact CE-CB 4.09Å; M408-C511 HydrophobicContact SD-CB 4.17Å; M408-Y514 HydrophobicContact CE-CD1 3.58Å; M408-Y514 HydrophobicContact CE-CE1 4.28Å; M408-Y514 HydrophobicContact CE-CG 4.41Å; M408-Y514 HydrophobicContact CG-CD1 4.16Å; M408-Y514 HydrophobicContact CG-CE1 4.18Å; M408-Y514 HydrophobicContact SD-CD1 3.89Å; M408-Y514 HydrophobicContact SD-CE1 4.5Å
409	G	91.4	Very high	89.6	Confident	28 Å²	28	50 Å²	50	29%	0.289	27%	0.27	S	S	.	.	H	α-helix	trans	-63.3	-51.4	172	0	0	0	0	0	112.3	V405 C406 A411 A412 V413	V405-G409 WeakPolarHBondContact O-CA 3.3Å; V405-G409 PolarHBondContact O-N 3.33Å; C406-G409 PolarHBondContact O-N 3Å; G409-A411 VanDerWaalsContact C-N 3.35Å; G409-A411 PolarHBondContact O-N 2.96Å; G409-A412 PolarHBondContact O-N 2.68Å; G409-V413 WeakPolarHBondContact O-CG2 3.43Å; G409-V413 PolarHBondContact O-N 3.2Å; G409-V413 VanDerWaalsContact O-N 3.08Å
410	G	92.7	Very high	90.2	Very high	0 Å²	0	49 Å²	49	0%	0	27%	0.267	C	S	.	.	H	α-helix	trans	-60.8	-42.6	176.3	0	0	0	0	0	112.7	C406 V413 H414 N451	C406-G410 PolarHBondContact O-N 3.07Å; G410-V413 PolarHBondContact O-N 3.39Å; G410-H414 PolarHBondContact O-N 2.85Å; G410-H414 VanDerWaalsContact O-N 3.1Å; G410-N451 VanDerWaalsContact C-OD1 3.26Å; G410-N451 WeakPolarHBondContact CA-OD1 3.5Å
411	A	93.9	Very high	90.5	Very high	3 Å²	3	37.9 Å²	37.9	3%	0.025	23%	0.225	C	C	.	.	H	α-helix	trans	-62.4	-41.2	174.7	0	0	0	0	0	113.3	L407 M408 G409 H414 G415 N451 L507 C511	L407-A411 VanDerWaalsContact O-CB 3.31Å; L407-A411 WeakPolarHBondContact O-CB 3.02Å; L407-A411 PolarHBondContact O-N 3.38Å; M408-A411 HydrophobicContact CE-CB 4.05Å; G409-A411 VanDerWaalsContact C-N 3.35Å; G409-A411 PolarHBondContact O-N 2.96Å; A411-H414 PolarHBondContact O-N 2.68Å; A411-G415 PolarHBondContact O-N 3.36Å; A411-N451 PolarHBondContact N-OD1 2.74Å; A411-N451 VanDerWaalsContact N-OD1 3.13Å; A411-L507 HydrophobicContact CB-CD1 3.72Å; A411-C511 VanDerWaalsContact CB-SG 3.6Å
412	A	95	Very high	90.9	Very high	60 Å²	60	36 Å²	36	50%	0.496	22%	0.215	S	C	.	.	H	α-helix	trans	-64.1	-42.3	177.1	0	0	0	0	0	112.1	M408 G409 G415 V416	M408-A412 VanDerWaalsContact O-CB 3.27Å; M408-A412 WeakPolarHBondContact O-CB 2.99Å; M408-A412 PolarHBondContact O-N 2.93Å; G409-A412 PolarHBondContact O-N 2.68Å; A412-G415 PolarHBondContact O-N 2.99Å; A412-V416 WeakPolarHBondContact O-CG2 3.11Å; A412-V416 PolarHBondContact O-N 3.46Å
413	V	95.6	Very high	91.1	Very high	39 Å²	39	36.3 Å²	36.3	24%	0.236	22%	0.223	C	C	.	.	H	α-helix	trans	-59.1	-49.8	175.2	173	0	0	0	0	110.6	G409 G410 G415 V416 L417 L443 L446	G409-V413 WeakPolarHBondContact O-CG2 3.43Å; G409-V413 PolarHBondContact O-N 3.2Å; G409-V413 VanDerWaalsContact O-N 3.08Å; G410-V413 PolarHBondContact O-N 3.39Å; V413-G415 VanDerWaalsContact C-N 3.34Å; V413-G415 PolarHBondContact O-N 2.76Å; V413-V416 PolarHBondContact O-N 3.11Å; V413-L417 HydrophobicContact CG1-CD1 3.98Å; V413-L417 VanDerWaalsContact O-CG 3.32Å; V413-L417 WeakPolarHBondContact O-CG 3.27Å; V413-L417 PolarHBondContact O-N 3.43Å; V413-L443 HydrophobicContact CG1-CB 4.39Å; V413-L443 VanDerWaalsContact CG1-O 3.23Å; V413-L443 WeakPolarHBondContact CG1-O 3.33Å; V413-L446 HydrophobicContact CG2-CD2 4.45Å
414	H	95.4	Very high	91.2	Very high	0 Å²	0	35.8 Å²	35.8	0%	0	22%	0.223	C	C	.	.	H	α-helix	trans	-63.7	-36.1	176.7	-73.5	174.2	0	0	0	113.4	Y351 E355 G410 A411 L417 L418 W444 G447 S448 N451 L507	Y351-H414 AromaticContact CE1-ND1 3.86Å; Y351-H414 AromaticContact CZ-ND1 3.92Å; Y351-H414 VanDerWaalsContact OH-CB 3.25Å; Y351-H414 WeakPolarHBondContact OH-CB 3.45Å; Y351-H414 PolarHBondContact OH-ND1 3.36Å; Y351-H414 VanDerWaalsContact OH-ND1 3.09Å; E355-H414 IonicContact OE1-CE1 2.98Å; E355-H414 IonicContact OE2-CE1 2.79Å; E355-H414 PolarHBondContact OE2-CE1 2.88Å; G410-H414 PolarHBondContact O-N 2.85Å; G410-H414 VanDerWaalsContact O-N 3.1Å; A411-H414 PolarHBondContact O-N 2.68Å; H414-L417 PolarHBondContact O-N 3.11Å; H414-L418 WeakPolarHBondContact O-CB 3.49Å; H414-L418 VanDerWaalsContact O-CG 3.3Å; H414-L418 WeakPolarHBondContact O-CG 3.45Å; H414-L418 PolarHBondContact O-N 2.87Å; H414-W444 VanDerWaalsContact NE2-CA 3.28Å; H414-W444 WeakPolarHBondContact NE2-CA 3.27Å; H414-W444 AromaticContact NE2-CD1 3.01Å; H414-W444 AromaticContact NE2-CD2 3.74Å; H414-W444 AromaticContact NE2-CE2 3.75Å; H414-W444 AromaticContact NE2-CG 3.3Å; H414-W444 VanDerWaalsContact NE2-CG 3.3Å; H414-W444 AromaticContact NE2-NE1 3.29Å; H414-W444 PolarHBondContact NE2-NE1 3.31Å; H414-W444 PolarHBondContact NE2-O 3.47Å; H414-G447 VanDerWaalsContact NE2-C 3.32Å; H414-G447 WeakPolarHBondContact NE2-CA 3.45Å; H414-S448 WeakPolarHBondContact CE1-CA 3.4Å; H414-S448 VanDerWaalsContact CE1-CB 3.4Å; H414-S448 WeakPolarHBondContact CE1-CB 3.44Å; H414-S448 PolarHBondContact CE1-N 3.39Å; H414-S448 PolarHBondContact CE1-OG 2.95Å; H414-S448 PolarHBondContact NE2-N 3.28Å; H414-S448 PolarHBondContact NE2-OG 2.84Å; H414-N451 PolarHBondContact ND1-ND2 3.08Å; H414-L507 HydrophobicContact CB-CD2 4.08Å
415	G	95.4	Very high	91	Very high	17 Å²	17	34.6 Å²	34.6	18%	0.175	23%	0.228	C	C	.	.	H	α-helix	trans	-60.9	-46	176.2	0	0	0	0	0	112.4	A411 A412 V413 L418 V419	A411-G415 PolarHBondContact O-N 3.36Å; A412-G415 PolarHBondContact O-N 2.99Å; V413-G415 VanDerWaalsContact C-N 3.34Å; V413-G415 PolarHBondContact O-N 2.76Å; G415-L418 PolarHBondContact O-N 3.3Å; G415-V419 WeakPolarHBondContact O-CG2 3.47Å; G415-V419 PolarHBondContact O-N 2.89Å
416	V	95.9	Very high	90.8	Very high	98 Å²	98	32.6 Å²	32.6	59%	0.594	22%	0.216	S	C	*	.	H	α-helix	trans	-62.9	-46.6	174.8	174.6	0	0	0	0	110.8	A412 V413 L418 V419 V420	A412-V416 WeakPolarHBondContact O-CG2 3.11Å; A412-V416 PolarHBondContact O-N 3.46Å; V413-V416 PolarHBondContact O-N 3.11Å; V416-L418 PolarHBondContact O-N 3.3Å; V416-V419 PolarHBondContact O-N 2.79Å; V416-V420 WeakPolarHBondContact O-CG2 3.36Å; V416-V420 PolarHBondContact O-N 3Å
417	L	95	Very high	90.4	Very high	10 Å²	10	39.8 Å²	39.8	5%	0.052	25%	0.246	C	C	.	.	H	α-helix	trans	-62.2	-41.5	179.1	-67.1	172.1	0	0	0	112.3	V413 H414 V419 V420 L421 I440 L443 W444	V413-L417 HydrophobicContact CG1-CD1 3.98Å; V413-L417 VanDerWaalsContact O-CG 3.32Å; V413-L417 WeakPolarHBondContact O-CG 3.27Å; V413-L417 PolarHBondContact O-N 3.43Å; H414-L417 PolarHBondContact O-N 3.11Å; L417-V419 VanDerWaalsContact C-N 3.33Å; L417-V419 PolarHBondContact O-N 3.41Å; L417-V420 PolarHBondContact O-N 2.84Å; L417-L421 VanDerWaalsContact O-CG 3.28Å; L417-L421 WeakPolarHBondContact O-CG 3.07Å; L417-L421 PolarHBondContact O-N 3.42Å; L417-I440 HydrophobicContact CD2-CG1 4.29Å; L417-I440 HydrophobicContact CD2-CG2 4.45Å; L417-L443 HydrophobicContact CD1-CB 3.83Å; L417-L443 HydrophobicContact CD2-CB 4.05Å; L417-L443 HydrophobicContact CD2-CD1 4.25Å; L417-L443 HydrophobicContact CG-CB 4.44Å; L417-W444 HydrophobicContact CB-CE3 3.95Å; L417-W444 HydrophobicContact CB-CZ3 4.04Å; L417-W444 HydrophobicContact CD1-CB 4.1Å; L417-W444 HydrophobicContact CD1-CD2 4.49Å; L417-W444 HydrophobicContact CD1-CE3 3.89Å
418	L	94.5	Very high	90.1	Very high	0 Å²	0	41.6 Å²	41.6	0%	0	26%	0.258	C	S	.	.	H	α-helix	trans	-60.9	-39.8	176.5	-78.1	168.3	0	0	0	112.2	H414 G415 V416 L421 L422 W444 L500 L503 L504 L507	H414-L418 WeakPolarHBondContact O-CB 3.49Å; H414-L418 VanDerWaalsContact O-CG 3.3Å; H414-L418 WeakPolarHBondContact O-CG 3.45Å; H414-L418 PolarHBondContact O-N 2.87Å; G415-L418 PolarHBondContact O-N 3.3Å; V416-L418 PolarHBondContact O-N 3.3Å; L418-L421 PolarHBondContact O-N 3.22Å; L418-L422 WeakPolarHBondContact O-CB 3.18Å; L418-L422 WeakPolarHBondContact O-CG 3.28Å; L418-L422 PolarHBondContact O-N 3.35Å; L418-W444 HydrophobicContact CD2-CH2 3.82Å; L418-W444 HydrophobicContact CD2-CZ3 4.25Å; L418-W444 HydrophobicContact CG-CH2 4.03Å; L418-W444 HydrophobicContact CG-CZ3 4.25Å; L418-L500 HydrophobicContact CD2-CD2 3.6Å; L418-L503 HydrophobicContact CD1-CB 4.19Å; L418-L503 HydrophobicContact CD2-CB 3.98Å; L418-L503 HydrophobicContact CD2-CD2 4.44Å; L418-L504 HydrophobicContact CB-CD1 4.29Å; L418-L504 HydrophobicContact CD1-CB 4.26Å; L418-L504 HydrophobicContact CD1-CD1 4.28Å; L418-L507 HydrophobicContact CD1-CD2 3.89Å
419	V	93.8	Very high	89.2	Confident	82 Å²	82	45.2 Å²	45.2	50%	0.497	28%	0.278	S	S	.	.	H	α-helix	trans	-66	-42.7	174.2	173.5	0	0	0	0	111.3	G415 V416 L417 L421 L422 A423 L504	G415-V419 WeakPolarHBondContact O-CG2 3.47Å; G415-V419 PolarHBondContact O-N 2.89Å; V416-V419 PolarHBondContact O-N 2.79Å; L417-V419 VanDerWaalsContact C-N 3.33Å; L417-V419 PolarHBondContact O-N 3.41Å; V419-L421 VanDerWaalsContact C-N 3.35Å; V419-L421 PolarHBondContact O-N 3.29Å; V419-L422 PolarHBondContact O-N 3.48Å; V419-A423 PolarHBondContact O-N 2.92Å; V419-A423 VanDerWaalsContact O-N 3.13Å; V419-L504 HydrophobicContact CG2-CD2 4.29Å
420	V	92.6	Very high	88.5	Confident	59 Å²	59	44.7 Å²	44.7	36%	0.358	27%	0.27	S	S	.	.	H	α-helix	trans	-60	-44.1	174.3	170.2	0	0	0	0	111.2	V416 L417 A423 M424 I440	V416-V420 WeakPolarHBondContact O-CG2 3.36Å; V416-V420 PolarHBondContact O-N 3Å; L417-V420 PolarHBondContact O-N 2.84Å; V420-A423 PolarHBondContact O-N 2.94Å; V420-M424 HydrophobicContact CG1-CE 4.27Å; V420-M424 VanDerWaalsContact O-CB 3.28Å; V420-M424 WeakPolarHBondContact O-CB 3.26Å; V420-M424 PolarHBondContact O-N 3.12Å; V420-I440 HydrophobicContact CG1-CD1 4.38Å
421	L	91.1	Very high	87.8	Confident	0 Å²	0	49.5 Å²	49.5	0%	0	30%	0.302	C	S	.	.	H	α-helix	trans	-68.7	-32.7	178.3	-66.1	178.2	0	0	0	113.2	F358 F363 Y367 L417 L418 V419 A423 I440 W444 L500	F358-L421 HydrophobicContact CE1-CD1 4.06Å; F358-L421 HydrophobicContact CZ-CD1 4.1Å; F363-L421 HydrophobicContact CD2-CD1 4Å; F363-L421 HydrophobicContact CD2-CD2 4.15Å; F363-L421 HydrophobicContact CE2-CD1 4.19Å; F363-L421 HydrophobicContact CE2-CD2 3.64Å; Y367-L421 HydrophobicContact CD1-CD2 4.42Å; Y367-L421 HydrophobicContact CE1-CD2 4.19Å; Y367-L421 PolarHBondContact OH-O 3.28Å; L417-L421 VanDerWaalsContact O-CG 3.28Å; L417-L421 WeakPolarHBondContact O-CG 3.07Å; L417-L421 PolarHBondContact O-N 3.42Å; L418-L421 PolarHBondContact O-N 3.22Å; V419-L421 VanDerWaalsContact C-N 3.35Å; V419-L421 PolarHBondContact O-N 3.29Å; L421-A423 VanDerWaalsContact C-N 3.33Å; L421-I440 HydrophobicContact CD2-CD1 4.25Å; L421-I440 HydrophobicContact CD2-CG2 4.35Å; L421-W444 HydrophobicContact CD1-CE3 4.43Å; L421-W444 HydrophobicContact CD1-CZ3 3.92Å; L421-L500 HydrophobicContact CB-CD1 4.26Å; L421-L500 HydrophobicContact CB-CD2 3.96Å; L421-L500 HydrophobicContact CD1-CD2 4.32Å
422	L	89.5	Confident	87.3	Confident	43 Å²	43	57.1 Å²	57.1	23%	0.225	34%	0.336	C	S	.	.	H	α-helix	trans	-65.4	-36.7	172.8	-80.6	166.1	0	0	0	112.3	L418 V419 L500 L504	L418-L422 WeakPolarHBondContact O-CB 3.18Å; L418-L422 WeakPolarHBondContact O-CG 3.28Å; L418-L422 PolarHBondContact O-N 3.35Å; V419-L422 PolarHBondContact O-N 3.48Å; L422-L500 HydrophobicContact CD2-CB 3.48Å; L422-L500 VanDerWaalsContact CD2-CB 3.48Å; L422-L500 HydrophobicContact CD2-CD1 3.95Å; L422-L500 HydrophobicContact CD2-CG 4.36Å; L422-L500 HydrophobicContact CG-CB 3.84Å; L422-L500 HydrophobicContact CG-CD1 4.17Å; L422-L504 HydrophobicContact CD1-CD2 4.13Å
423	A	87.9	Confident	86.8	Confident	77 Å²	77	58 Å²	58	64%	0.636	33%	0.328	S	S	*	.	H	α-helix	trans	-80.4	-30.1	177.9	0	0	0	0	0	113.4	V419 V420 L421 T425	V419-A423 PolarHBondContact O-N 2.92Å; V419-A423 VanDerWaalsContact O-N 3.13Å; V420-A423 PolarHBondContact O-N 2.94Å; L421-A423 VanDerWaalsContact C-N 3.33Å; A423-T425 PolarHBondContact O-N 3.36Å
424	M	84.1	Confident	86.4	Confident	33 Å²	33	59.2 Å²	59.2	16%	0.163	33%	0.332	C	S	.	.			trans	-73.9	109	-174	-173.7	178.2	-74.7	0	0	112.8	V420 V426 I440	V420-M424 HydrophobicContact CG1-CE 4.27Å; V420-M424 VanDerWaalsContact O-CB 3.28Å; V420-M424 WeakPolarHBondContact O-CB 3.26Å; V420-M424 PolarHBondContact O-N 3.12Å; M424-V426 HydrophobicContact CG-CG2 3.93Å; M424-V426 HydrophobicContact SD-CG2 4.06Å; M424-I440 HydrophobicContact CE-CD1 3.77Å; M424-I440 HydrophobicContact SD-CD1 4.35Å
425	T	78.5	Confident	86.2	Confident	87 Å²	87	61.2 Å²	61.2	53%	0.534	35%	0.353	S	S	.	.	E	Extended strand (participates in β ladder)	trans	-95	114.5	166.7	55.8	0	0	0	0	110.4	A423	A423-T425 PolarHBondContact O-N 3.36Å
426	V	80.8	Confident	86	Confident	5 Å²	5	63.3 Å²	63.3	3%	0.03	36%	0.363	C	S	.	.	E	Extended strand (participates in β ladder)	trans	-93.1	133.6	-178.3	176.3	0	0	0	0	110.6	C262 Y367 C370 I371 M424	C262-V426 HydrophobicContact CB-CB 4.01Å; C262-V426 HydrophobicContact CB-CG1 4.14Å; C262-V426 WeakPolarHBondContact CB-O 3.12Å; C262-V426 PolarHBondContact N-O 3.26Å; Y367-V426 HydrophobicContact CD1-CG2 3.83Å; Y367-V426 HydrophobicContact CE1-CG2 4.3Å; C370-V426 HydrophobicContact CB-CG1 4.36Å; I371-V426 HydrophobicContact CD1-CG1 3.74Å; I371-V426 HydrophobicContact CD1-CG2 4.26Å; I371-V426 HydrophobicContact CG1-CG1 3.6Å; M424-V426 HydrophobicContact CG-CG2 3.93Å; M424-V426 HydrophobicContact SD-CG2 4.06Å
427	K	78.2	Confident	85.7	Confident	159 Å²	159	58.9 Å²	58.9	69%	0.691	34%	0.336	S	S	*	.	P	Polyproline II helix	trans	-92.1	141.6	166.6	-69.9	-178.5	-179.2	176.1	0	109.8	S430	K427-S430 PolarHBondContact O-OG 2.92Å
428	P	78.9	Confident	85.6	Confident	39 Å²	39	60.7 Å²	60.7	25%	0.253	35%	0.346	S	S	.	.	T	Hydrogen-bonded Turn	trans	-62	148.7	177.3	29.6	-37.6	0	0	0	111.8	V259 C370 S430	V259-P428 WeakPolarHBondContact O-CG 3.36Å; C370-P428 WeakPolarHBondContact SG-CA 3.37Å; P428-S430 VanDerWaalsContact C-N 3.32Å; P428-S430 PolarHBondContact O-N 3.4Å
429	N	72.5	Confident	85.6	Confident	111 Å²	111	64.8 Å²	64.8	59%	0.594	37%	0.37	S	S	*	.	T	Hydrogen-bonded Turn	trans	56.2	38.6	172.7	-160.7	36.8	0	0	0	114.7	C370 P431	C370-N429 PolarHBondContact O-N 3.45Å; N429-P431 WeakPolarHBondContact O-CD 3.33Å
430	S	76.9	Confident	85.7	Confident	16 Å²	16	61.3 Å²	61.3	11%	0.112	35%	0.349	C	S	.	.			trans	-106.9	97.8	179.6	54.3	0	0	0	0	111.5	K427 P428 E432 Y433	K427-S430 PolarHBondContact O-OG 2.92Å; P428-S430 VanDerWaalsContact C-N 3.32Å; P428-S430 PolarHBondContact O-N 3.4Å; S430-E432 PolarHBondContact O-N 3.38Å; S430-Y433 PolarHBondContact O-N 3.04Å; S430-Y433 VanDerWaalsContact OG-CD2 3.27Å; S430-Y433 WeakPolarHBondContact OG-CD2 3.41Å
431	P	78.6	Confident	85.8	Confident	102 Å²	102	58.6 Å²	58.6	66%	0.662	33%	0.332	S	S	*	.	G	3₁₀ helix	trans	-66	-21.6	-174.1	26.5	-35	0	0	0	113.5	N429 Y433 L434	N429-P431 WeakPolarHBondContact O-CD 3.33Å; P431-Y433 PolarHBondContact O-N 3.5Å; P431-L434 VanDerWaalsContact O-CB 3.23Å; P431-L434 WeakPolarHBondContact O-CB 3.44Å; P431-L434 PolarHBondContact O-N 2.99Å; P431-L434 VanDerWaalsContact O-N 3.09Å
432	E	83.9	Confident	86	Confident	162 Å²	162	61.2 Å²	61.2	76%	0.757	35%	0.348	S	S	*	.	G	3₁₀ helix	trans	-54.6	-32.1	175.6	-62.6	171.2	-177.1	0	0	113.1	S430 L434	S430-E432 PolarHBondContact O-N 3.38Å; E432-L434 VanDerWaalsContact C-N 3.33Å; E432-L434 PolarHBondContact O-N 3.04Å
433	Y	84.4	Confident	86.4	Confident	80 Å²	80	62.4 Å²	62.4	31%	0.314	36%	0.355	S	S	.	.	G	3₁₀ helix	trans	-84.2	-3.6	-177.9	-68.8	-94.7	0	0	0	113.6	S430 P431 P436 L437	S430-Y433 PolarHBondContact O-N 3.04Å; S430-Y433 VanDerWaalsContact OG-CD2 3.27Å; S430-Y433 WeakPolarHBondContact OG-CD2 3.41Å; P431-Y433 PolarHBondContact O-N 3.5Å; Y433-P436 WeakPolarHBondContact O-CD 3.4Å; Y433-L437 VanDerWaalsContact O-CB 3.22Å; Y433-L437 WeakPolarHBondContact O-CB 3.45Å; Y433-L437 PolarHBondContact O-N 3.39Å
434	L	87.3	Confident	86.8	Confident	64 Å²	64	58.8 Å²	58.8	34%	0.335	32%	0.324	S	S	.	.	H	α-helix	trans	-61.2	-48.2	-179.4	177.1	58.5	0	0	0	112.6	L372 P431 E432 L437 L438	L372-L434 HydrophobicContact CD1-CD1 4.36Å; L372-L434 HydrophobicContact CD2-CD1 3.61Å; L372-L434 HydrophobicContact CG-CD1 4.04Å; P431-L434 VanDerWaalsContact O-CB 3.23Å; P431-L434 WeakPolarHBondContact O-CB 3.44Å; P431-L434 PolarHBondContact O-N 2.99Å; P431-L434 VanDerWaalsContact O-N 3.09Å; E432-L434 VanDerWaalsContact C-N 3.33Å; E432-L434 PolarHBondContact O-N 3.04Å; L434-L437 PolarHBondContact O-N 2.94Å; L434-L438 HydrophobicContact CD1-CD1 4.13Å; L434-L438 HydrophobicContact CD1-CG 4.24Å; L434-L438 HydrophobicContact CG-CD1 4.34Å; L434-L438 WeakPolarHBondContact O-CG 3.45Å; L434-L438 PolarHBondContact O-N 3.16Å
435	G	90.4	Very high	87.3	Confident	41 Å²	41	57.2 Å²	57.2	42%	0.423	32%	0.317	S	S	.	.	H	α-helix	trans	-59	-55.5	177.8	0	0	0	0	0	112.4	L437 L438 V439	G435-L437 VanDerWaalsContact C-N 3.29Å; G435-L437 PolarHBondContact O-N 2.99Å; G435-L438 PolarHBondContact O-N 3.39Å; G435-V439 WeakPolarHBondContact O-CG2 3.47Å; G435-V439 PolarHBondContact O-N 2.85Å
436	P	90.6	Very high	88.1	Confident	62 Å²	62	54.4 Å²	54.4	40%	0.403	30%	0.298	S	S	.	.	H	α-helix	trans	-53.6	-40.5	173.9	-29.4	35.7	0	0	0	114.1	Y433 V439 I440	Y433-P436 WeakPolarHBondContact O-CD 3.4Å; P436-V439 PolarHBondContact O-N 3.38Å; P436-I440 VanDerWaalsContact O-CG1 3.29Å; P436-I440 WeakPolarHBondContact O-CG1 3.26Å; P436-I440 PolarHBondContact O-N 3.13Å
437	L	90.8	Very high	88.8	Confident	4 Å²	4	54.1 Å²	54.1	2%	0.021	30%	0.297	C	S	.	.	H	α-helix	trans	-63.2	-44.5	178.8	-172.9	79.7	0	0	0	112.1	F363 I371 L372 L380 Y433 L434 G435 I440 M441	F363-L437 HydrophobicContact CE1-CD1 3.85Å; F363-L437 HydrophobicContact CE1-CG 4.48Å; F363-L437 HydrophobicContact CE2-CD1 4.24Å; F363-L437 HydrophobicContact CZ-CD1 3.37Å; F363-L437 HydrophobicContact CZ-CG 4.27Å; I371-L437 HydrophobicContact CB-CD2 4.29Å; I371-L437 HydrophobicContact CD1-CB 4.45Å; I371-L437 HydrophobicContact CD1-CD1 4.01Å; I371-L437 HydrophobicContact CD1-CD2 4.21Å; I371-L437 HydrophobicContact CD1-CG 4.47Å; I371-L437 HydrophobicContact CG2-CD2 4.4Å; L372-L437 HydrophobicContact CD1-CD2 3.67Å; L372-L437 HydrophobicContact CG-CD2 4.28Å; L380-L437 HydrophobicContact CD1-CD2 3.72Å; L380-L437 HydrophobicContact CD1-CG 3.86Å; Y433-L437 VanDerWaalsContact O-CB 3.22Å; Y433-L437 WeakPolarHBondContact O-CB 3.45Å; Y433-L437 PolarHBondContact O-N 3.39Å; L434-L437 PolarHBondContact O-N 2.94Å; G435-L437 VanDerWaalsContact C-N 3.29Å; G435-L437 PolarHBondContact O-N 2.99Å; L437-I440 PolarHBondContact O-N 3.37Å; L437-M441 PolarHBondContact O-N 3.5Å
438	L	92.9	Very high	89.6	Confident	49 Å²	49	46.8 Å²	46.8	26%	0.257	27%	0.265	S	S	.	.	H	α-helix	trans	-66.4	-40.1	176.7	-67.6	174.6	0	0	0	111.8	L380 V383 L434 G435 I440 M441 V442	L380-L438 HydrophobicContact CD1-CD2 4.49Å; V383-L438 HydrophobicContact CG2-CD2 4.32Å; L434-L438 HydrophobicContact CD1-CD1 4.13Å; L434-L438 HydrophobicContact CD1-CG 4.24Å; L434-L438 HydrophobicContact CG-CD1 4.34Å; L434-L438 WeakPolarHBondContact O-CG 3.45Å; L434-L438 PolarHBondContact O-N 3.16Å; G435-L438 PolarHBondContact O-N 3.39Å; L438-I440 VanDerWaalsContact C-N 3.33Å; L438-I440 PolarHBondContact O-N 2.99Å; L438-M441 PolarHBondContact O-N 3.04Å; L438-V442 WeakPolarHBondContact O-CG2 3.34Å; L438-V442 PolarHBondContact O-N 3.14Å
439	V	94.9	Very high	90.3	Very high	85 Å²	85	45 Å²	45	52%	0.515	25%	0.254	S	S	.	.	H	α-helix	trans	-61.2	-42.5	174.1	172.4	0	0	0	0	111.1	G435 P436 M441 V442 L443	G435-V439 WeakPolarHBondContact O-CG2 3.47Å; G435-V439 PolarHBondContact O-N 2.85Å; P436-V439 PolarHBondContact O-N 3.38Å; V439-M441 VanDerWaalsContact C-N 3.34Å; V439-M441 PolarHBondContact O-N 3.26Å; V439-V442 PolarHBondContact O-N 2.99Å; V439-L443 HydrophobicContact CG1-CD1 3.9Å; V439-L443 HydrophobicContact CG1-CG 4.37Å; V439-L443 WeakPolarHBondContact O-CG 3.47Å; V439-L443 PolarHBondContact O-N 3.02Å
440	I	94.4	Very high	91.3	Very high	10 Å²	10	40.3 Å²	40.3	5%	0.051	23%	0.229	C	C	.	.	H	α-helix	trans	-59.6	-42.9	174.4	-72.8	165.1	0	0	0	111	F363 L417 V420 L421 M424 P436 L437 L438 L443 W444	F363-I440 HydrophobicContact CE2-CG2 3.84Å; F363-I440 HydrophobicContact CZ-CB 4.47Å; F363-I440 HydrophobicContact CZ-CG2 3.74Å; L417-I440 HydrophobicContact CD2-CG1 4.29Å; L417-I440 HydrophobicContact CD2-CG2 4.45Å; V420-I440 HydrophobicContact CG1-CD1 4.38Å; L421-I440 HydrophobicContact CD2-CD1 4.25Å; L421-I440 HydrophobicContact CD2-CG2 4.35Å; M424-I440 HydrophobicContact CE-CD1 3.77Å; M424-I440 HydrophobicContact SD-CD1 4.35Å; P436-I440 VanDerWaalsContact O-CG1 3.29Å; P436-I440 WeakPolarHBondContact O-CG1 3.26Å; P436-I440 PolarHBondContact O-N 3.13Å; L437-I440 PolarHBondContact O-N 3.37Å; L438-I440 VanDerWaalsContact C-N 3.33Å; L438-I440 PolarHBondContact O-N 2.99Å; I440-L443 PolarHBondContact O-N 3.32Å; I440-W444 VanDerWaalsContact O-CB 3.28Å; I440-W444 WeakPolarHBondContact O-CB 3.24Å; I440-W444 PolarHBondContact O-N 2.87Å
441	M	94.9	Very high	92	Very high	1 Å²	1	39.6 Å²	39.6	1%	0.005	22%	0.223	C	C	.	.	H	α-helix	trans	-64.9	-40.5	176.7	-71.2	-55.3	-84.1	0	0	113.4	I359 F363 L380 V383 Y384 L437 L438 V439 W444 G445	I359-M441 HydrophobicContact CD1-CE 3.79Å; I359-M441 HydrophobicContact CD1-SD 3.47Å; I359-M441 WeakPolarHBondContact CD1-SD 3.48Å; I359-M441 HydrophobicContact CG1-CE 3.79Å; I359-M441 HydrophobicContact CG1-SD 4.17Å; F363-M441 HydrophobicContact CD1-CE 4.36Å; F363-M441 HydrophobicContact CD1-SD 3.42Å; F363-M441 WeakPolarHBondContact CD1-SD 3.45Å; F363-M441 HydrophobicContact CE1-CE 4.47Å; F363-M441 HydrophobicContact CE1-CG 3.86Å; F363-M441 HydrophobicContact CE1-SD 3.15Å; F363-M441 WeakPolarHBondContact CE1-SD 3.42Å; F363-M441 HydrophobicContact CG-SD 4.5Å; F363-M441 HydrophobicContact CZ-SD 4.07Å; L380-M441 HydrophobicContact CD1-CG 3.38Å; L380-M441 HydrophobicContact CD1-SD 4.28Å; L380-M441 HydrophobicContact CD2-CE 4.4Å; L380-M441 HydrophobicContact CD2-SD 4.48Å; L380-M441 HydrophobicContact CG-CE 3.81Å; L380-M441 HydrophobicContact CG-CG 3.69Å; L380-M441 HydrophobicContact CG-SD 4.03Å; L380-M441 WeakPolarHBondContact O-CE 3.48Å; V383-M441 HydrophobicContact CG1-CB 4.28Å; Y384-M441 VanDerWaalsContact CB-CE 3.47Å; Y384-M441 HydrophobicContact CD2-CE 4.47Å; Y384-M441 HydrophobicContact CG-CE 4.1Å; L437-M441 PolarHBondContact O-N 3.5Å; L438-M441 PolarHBondContact O-N 3.04Å; V439-M441 VanDerWaalsContact C-N 3.34Å; V439-M441 PolarHBondContact O-N 3.26Å; M441-W444 PolarHBondContact O-N 3.48Å; M441-G445 PolarHBondContact O-N 3.08Å
442	V	96.6	Very high	92.6	Very high	55 Å²	55	35.9 Å²	35.9	33%	0.333	20%	0.197	S	C	.	.	H	α-helix	trans	-64.5	-45.2	177	174.3	0	0	0	0	110.4	V383 S387 F391 L438 V439 G445 L446	V383-V442 HydrophobicContact CG1-CG2 3.61Å; S387-V442 PolarHBondContact OG-O 3.37Å; F391-V442 HydrophobicContact CE2-CG1 3.87Å; F391-V442 HydrophobicContact CZ-CG1 4.3Å; L438-V442 WeakPolarHBondContact O-CG2 3.34Å; L438-V442 PolarHBondContact O-N 3.14Å; V439-V442 PolarHBondContact O-N 2.99Å; V442-G445 PolarHBondContact O-N 2.84Å; V442-L446 PolarHBondContact O-N 3.06Å
443	L	96.4	Very high	93	Very high	69 Å²	69	28.2 Å²	28.2	36%	0.361	16%	0.161	S	C	.	.	H	α-helix	trans	-69.1	-33.2	177.1	-66	175	0	0	0	112.6	V413 L417 V439 I440 L446 G447	V413-L443 HydrophobicContact CG1-CB 4.39Å; V413-L443 VanDerWaalsContact CG1-O 3.23Å; V413-L443 WeakPolarHBondContact CG1-O 3.33Å; L417-L443 HydrophobicContact CD1-CB 3.83Å; L417-L443 HydrophobicContact CD2-CB 4.05Å; L417-L443 HydrophobicContact CD2-CD1 4.25Å; L417-L443 HydrophobicContact CG-CB 4.44Å; V439-L443 HydrophobicContact CG1-CD1 3.9Å; V439-L443 HydrophobicContact CG1-CG 4.37Å; V439-L443 WeakPolarHBondContact O-CG 3.47Å; V439-L443 PolarHBondContact O-N 3.02Å; I440-L443 PolarHBondContact O-N 3.32Å; L443-L446 HydrophobicContact CD2-CD2 4.39Å; L443-L446 WeakPolarHBondContact O-CB 3.22Å; L443-L446 PolarHBondContact O-N 2.78Å; L443-G447 PolarHBondContact O-N 2.94Å; L443-G447 VanDerWaalsContact O-N 3.1Å
444	W	96.1	Very high	93.2	Very high	0 Å²	0	24.4 Å²	24.4	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-66.6	-43.4	173.4	-161.4	-74.2	0	0	0	110.7	E355 F358 I359 H414 L417 L418 L421 I440 M441 L446 G447 S448	E355-W444 HydrophobicContact CB-CZ2 4.2Å; F358-W444 AromaticContact CD1-CH2 3.7Å; F358-W444 HydrophobicContact CD1-CH2 3.7Å; F358-W444 AromaticContact CD1-CZ2 3.61Å; F358-W444 HydrophobicContact CD1-CZ2 3.61Å; F358-W444 HydrophobicContact CD1-CZ3 4.49Å; F358-W444 AromaticContact CE1-CH2 3.64Å; F358-W444 HydrophobicContact CE1-CH2 3.64Å; F358-W444 HydrophobicContact CE1-CZ2 4.02Å; F358-W444 HydrophobicContact CE1-CZ3 4.07Å; I359-W444 HydrophobicContact CD1-CB 4.12Å; I359-W444 HydrophobicContact CD1-CD2 3.95Å; I359-W444 HydrophobicContact CD1-CG 3.6Å; I359-W444 HydrophobicContact CG1-CG 4.14Å; H414-W444 VanDerWaalsContact NE2-CA 3.28Å; H414-W444 WeakPolarHBondContact NE2-CA 3.27Å; H414-W444 AromaticContact NE2-CD1 3.01Å; H414-W444 AromaticContact NE2-CD2 3.74Å; H414-W444 AromaticContact NE2-CE2 3.75Å; H414-W444 AromaticContact NE2-CG 3.3Å; H414-W444 VanDerWaalsContact NE2-CG 3.3Å; H414-W444 AromaticContact NE2-NE1 3.29Å; H414-W444 PolarHBondContact NE2-NE1 3.31Å; H414-W444 PolarHBondContact NE2-O 3.47Å; L417-W444 HydrophobicContact CB-CE3 3.95Å; L417-W444 HydrophobicContact CB-CZ3 4.04Å; L417-W444 HydrophobicContact CD1-CB 4.1Å; L417-W444 HydrophobicContact CD1-CD2 4.49Å; L417-W444 HydrophobicContact CD1-CE3 3.89Å; L418-W444 HydrophobicContact CD2-CH2 3.82Å; L418-W444 HydrophobicContact CD2-CZ3 4.25Å; L418-W444 HydrophobicContact CG-CH2 4.03Å; L418-W444 HydrophobicContact CG-CZ3 4.25Å; L421-W444 HydrophobicContact CD1-CE3 4.43Å; L421-W444 HydrophobicContact CD1-CZ3 3.92Å; I440-W444 VanDerWaalsContact O-CB 3.28Å; I440-W444 WeakPolarHBondContact O-CB 3.24Å; I440-W444 PolarHBondContact O-N 2.87Å; M441-W444 PolarHBondContact O-N 3.48Å; W444-L446 VanDerWaalsContact C-N 3.34Å; W444-L446 PolarHBondContact O-N 2.75Å; W444-G447 PolarHBondContact O-N 3.29Å; W444-G447 VanDerWaalsContact O-N 3.15Å; W444-S448 VanDerWaalsContact CD1-OG 3.22Å; W444-S448 PolarHBondContact NE1-OG 3.29Å; W444-S448 WeakPolarHBondContact O-CB 3.3Å; W444-S448 PolarHBondContact O-N 3.16Å; W444-S448 PolarHBondContact O-OG 2.01Å
445	G	95.9	Very high	93.4	Very high	0 Å²	0	21.4 Å²	21.4	0%	0	13%	0.131	C	C	.	.	H	α-helix	trans	-61.9	-37.1	175.1	0	0	0	0	0	113.5	C388 M441 V442 A449	C388-G445 WeakPolarHBondContact SG-CA 3.22Å; C388-G445 PolarHBondContact SG-O 3.16Å; M441-G445 PolarHBondContact O-N 3.08Å; V442-G445 PolarHBondContact O-N 2.84Å; G445-A449 VanDerWaalsContact O-CB 3.26Å; G445-A449 WeakPolarHBondContact O-CB 3.47Å; G445-A449 PolarHBondContact O-N 2.83Å
446	L	95.4	Very high	93.5	Very high	28 Å²	28	19.6 Å²	19.6	15%	0.147	11%	0.112	C	C	.	.	H	α-helix	trans	-57.4	-51.3	169	170.9	61.4	0	0	0	111.5	F391 L394 V413 V442 L443 W444 L450	F391-L446 HydrophobicContact CB-CB 4.49Å; F391-L446 HydrophobicContact CB-CD1 3.85Å; F391-L446 HydrophobicContact CD1-CD1 3.69Å; F391-L446 VanDerWaalsContact CD2-CA 3.47Å; F391-L446 HydrophobicContact CD2-CB 3.52Å; F391-L446 HydrophobicContact CD2-CD1 4.04Å; F391-L446 HydrophobicContact CD2-CG 4.35Å; F391-L446 HydrophobicContact CE1-CD1 4.21Å; F391-L446 HydrophobicContact CE2-CB 3.77Å; F391-L446 HydrophobicContact CG-CB 4Å; F391-L446 HydrophobicContact CG-CD1 3.6Å; F391-L446 HydrophobicContact CG-CG 4.39Å; F391-L446 HydrophobicContact CZ-CB 4.45Å; L394-L446 HydrophobicContact CD2-CD1 3.84Å; V413-L446 HydrophobicContact CG2-CD2 4.45Å; V442-L446 PolarHBondContact O-N 3.06Å; L443-L446 HydrophobicContact CD2-CD2 4.39Å; L443-L446 WeakPolarHBondContact O-CB 3.22Å; L443-L446 PolarHBondContact O-N 2.78Å; W444-L446 VanDerWaalsContact C-N 3.34Å; W444-L446 PolarHBondContact O-N 2.75Å; L446-L450 HydrophobicContact CD1-CD1 3.77Å; L446-L450 HydrophobicContact CD1-CG 4.18Å; L446-L450 HydrophobicContact CG-CD1 4.22Å; L446-L450 WeakPolarHBondContact O-CG 3.44Å; L446-L450 PolarHBondContact O-N 3.05Å
447	G	94.6	Very high	93.5	Very high	0 Å²	0	16.7 Å²	16.7	0%	0	9%	0.093	C	C	.	.	H	α-helix	trans	-64.4	-43.6	179.6	0	0	0	0	0	112.8	H414 L443 W444 L450 N451	H414-G447 VanDerWaalsContact NE2-C 3.32Å; H414-G447 WeakPolarHBondContact NE2-CA 3.45Å; L443-G447 PolarHBondContact O-N 2.94Å; L443-G447 VanDerWaalsContact O-N 3.1Å; W444-G447 PolarHBondContact O-N 3.29Å; W444-G447 VanDerWaalsContact O-N 3.15Å; G447-L450 PolarHBondContact O-N 3.1Å; G447-N451 VanDerWaalsContact O-CB 3.22Å; G447-N451 WeakPolarHBondContact O-CB 3.29Å; G447-N451 PolarHBondContact O-N 2.84Å; G447-N451 PolarHBondContact O-ND2 3.36Å
448	S	94.6	Very high	93.5	Very high	4 Å²	4	16.5 Å²	16.5	3%	0.028	9%	0.092	C	C	.	.	H	α-helix	trans	-66.4	-38.9	179.2	-63.1	0	0	0	0	111.4	E355 H414 W444 K452	E355-S448 WeakPolarHBondContact OE2-CB 3.26Å; E355-S448 PolarHBondContact OE2-OG 2.92Å; H414-S448 WeakPolarHBondContact CE1-CA 3.4Å; H414-S448 VanDerWaalsContact CE1-CB 3.4Å; H414-S448 WeakPolarHBondContact CE1-CB 3.44Å; H414-S448 PolarHBondContact CE1-N 3.39Å; H414-S448 PolarHBondContact CE1-OG 2.95Å; H414-S448 PolarHBondContact NE2-N 3.28Å; H414-S448 PolarHBondContact NE2-OG 2.84Å; W444-S448 VanDerWaalsContact CD1-OG 3.22Å; W444-S448 PolarHBondContact NE1-OG 3.29Å; W444-S448 WeakPolarHBondContact O-CB 3.3Å; W444-S448 PolarHBondContact O-N 3.16Å; W444-S448 PolarHBondContact O-OG 2.01Å; S448-K452 WeakPolarHBondContact O-CB 3.34Å; S448-K452 PolarHBondContact O-N 2.96Å
449	A	93.9	Very high	93.4	Very high	1 Å²	1	14.2 Å²	14.2	1%	0.008	8%	0.08	C	C	.	.	H	α-helix	trans	-61.6	-52.4	172.2	0	0	0	0	0	111.7	F391 G445 N451 T453	F391-A449 HydrophobicContact CB-CB 3.96Å; G445-A449 VanDerWaalsContact O-CB 3.26Å; G445-A449 WeakPolarHBondContact O-CB 3.47Å; G445-A449 PolarHBondContact O-N 2.83Å; A449-N451 VanDerWaalsContact C-N 3.32Å; A449-N451 PolarHBondContact O-N 3.24Å; A449-T453 WeakPolarHBondContact O-CB 3.49Å; A449-T453 PolarHBondContact O-N 3Å; A449-T453 PolarHBondContact O-OG1 3Å
450	L	92.9	Very high	93.2	Very high	14 Å²	14	10.1 Å²	10.1	7%	0.073	6%	0.055	C	C	.	.	H	α-helix	trans	-61.5	-39.3	179.8	-68.2	174.1	0	0	0	112.3	L394 C406 L446 G447 G454	L394-L450 HydrophobicContact CB-CD2 4.31Å; L394-L450 HydrophobicContact CD2-CD2 4.19Å; L394-L450 HydrophobicContact CG-CD2 4.17Å; C406-L450 VanDerWaalsContact SG-CD2 3.56Å; C406-L450 PolarHBondContact SG-O 2.86Å; L446-L450 HydrophobicContact CD1-CD1 3.77Å; L446-L450 HydrophobicContact CD1-CG 4.18Å; L446-L450 HydrophobicContact CG-CD1 4.22Å; L446-L450 WeakPolarHBondContact O-CG 3.44Å; L446-L450 PolarHBondContact O-N 3.05Å; G447-L450 PolarHBondContact O-N 3.1Å; L450-G454 WeakPolarHBondContact O-CA 3.44Å; L450-G454 PolarHBondContact O-N 2.91Å
451	N	93	Very high	92.9	Very high	0 Å²	0	10.1 Å²	10.1	0%	0	6%	0.055	C	C	.	.	H	α-helix	trans	-72.5	-56.2	178.8	-70.8	-21.8	0	0	0	111.6	F348 L407 G410 A411 H414 G447 A449 G454 V455	F348-N451 HydrophobicContact CE1-CB 4.08Å; F348-N451 HydrophobicContact CZ-CB 4.26Å; L407-N451 PolarHBondContact O-OD1 2.7Å; G410-N451 VanDerWaalsContact C-OD1 3.26Å; G410-N451 WeakPolarHBondContact CA-OD1 3.5Å; A411-N451 PolarHBondContact N-OD1 2.74Å; A411-N451 VanDerWaalsContact N-OD1 3.13Å; H414-N451 PolarHBondContact ND1-ND2 3.08Å; G447-N451 VanDerWaalsContact O-CB 3.22Å; G447-N451 WeakPolarHBondContact O-CB 3.29Å; G447-N451 PolarHBondContact O-N 2.84Å; G447-N451 PolarHBondContact O-ND2 3.36Å; A449-N451 VanDerWaalsContact C-N 3.32Å; A449-N451 PolarHBondContact O-N 3.24Å; N451-G454 PolarHBondContact O-N 2.92Å; N451-V455 VanDerWaalsContact O-CG2 3.29Å; N451-V455 WeakPolarHBondContact O-CG2 3.46Å; N451-V455 PolarHBondContact O-N 2.78Å
452	K	90.9	Very high	92.5	Very high	25 Å²	25	10.9 Å²	10.9	11%	0.109	6%	0.059	C	C	.	.	H	α-helix	trans	-63.9	-48.3	-176.2	-164.9	79	167.9	-169.8	0	112.1	F227 S352 M356 S448 S456	F227-K452 HydrophobicContact CD1-CG 4.38Å; F227-K452 HydrophobicContact CE1-CG 3.72Å; F227-K452 HydrophobicContact CZ-CG 4.28Å; S352-K452 WeakPolarHBondContact OG-CD 3.36Å; M356-K452 PolarHBondContact SD-NZ 3.14Å; S448-K452 WeakPolarHBondContact O-CB 3.34Å; S448-K452 PolarHBondContact O-N 2.96Å; K452-S456 PolarHBondContact O-N 2.85Å
453	T	91.4	Very high	92	Very high	0 Å²	0	8.3 Å²	8.3	0%	0	4%	0.043	C	C	.	.	H	α-helix	trans	-68.4	-39.7	177	-49.7	0	0	0	0	110.5	F227 S392 S395 A449 S456 T457	F227-T453 HydrophobicContact CB-CG2 4.15Å; F227-T453 WeakPolarHBondContact CB-OG1 3.47Å; F227-T453 HydrophobicContact CD2-CG2 3.77Å; F227-T453 HydrophobicContact CG-CG2 4.19Å; F227-T453 WeakPolarHBondContact CG-OG1 3.49Å; S392-T453 PolarHBondContact OG-OG1 3.43Å; S395-T453 VanDerWaalsContact OG-CG2 3.31Å; S395-T453 WeakPolarHBondContact OG-CG2 3.4Å; A449-T453 WeakPolarHBondContact O-CB 3.49Å; A449-T453 PolarHBondContact O-N 3Å; A449-T453 PolarHBondContact O-OG1 3Å; T453-S456 PolarHBondContact O-N 3.14Å; T453-T457 WeakPolarHBondContact O-CB 3.48Å; T453-T457 PolarHBondContact O-N 3.39Å; T453-T457 PolarHBondContact O-OG1 3.49Å
454	G	90.4	Very high	91.3	Very high	1 Å²	1	5.2 Å²	5.2	1%	0.01	3%	0.028	C	C	.	.	H	α-helix	trans	-61.9	-45.7	177.8	0	0	0	0	0	113.4	L450 N451 T457 V458	L450-G454 WeakPolarHBondContact O-CA 3.44Å; L450-G454 PolarHBondContact O-N 2.91Å; N451-G454 PolarHBondContact O-N 2.92Å; G454-T457 PolarHBondContact O-N 2.98Å; G454-V458 WeakPolarHBondContact O-CB 3.47Å; G454-V458 WeakPolarHBondContact O-CG2 3.39Å; G454-V458 PolarHBondContact O-N 3.21Å
455	V	91.4	Very high	90.3	Very high	0 Å²	0	8 Å²	8	0%	0	4%	0.041	C	C	.	.	H	α-helix	trans	-59.8	-51.3	175.3	172.6	0	0	0	0	111.2	F348 F349 L407 N451 T457 V458 V459 Y477	F348-V455 HydrophobicContact CD1-CG2 3.26Å; F348-V455 HydrophobicContact CE1-CG2 3.45Å; F348-V455 VanDerWaalsContact CE1-CG2 3.45Å; F348-V455 HydrophobicContact CG-CG2 4.28Å; F349-V455 HydrophobicContact CD1-CG1 3.8Å; F349-V455 HydrophobicContact CE1-CG1 3.66Å; L407-V455 HydrophobicContact CD1-CG2 3.87Å; N451-V455 VanDerWaalsContact O-CG2 3.29Å; N451-V455 WeakPolarHBondContact O-CG2 3.46Å; N451-V455 PolarHBondContact O-N 2.78Å; V455-T457 VanDerWaalsContact C-N 3.27Å; V455-T457 PolarHBondContact O-N 3.3Å; V455-V458 PolarHBondContact O-N 3.26Å; V455-V459 HydrophobicContact CG1-CG2 4.31Å; V455-V459 WeakPolarHBondContact O-CB 3.5Å; V455-V459 WeakPolarHBondContact O-CG2 3.27Å; V455-V459 PolarHBondContact O-N 2.87Å; V455-Y477 HydrophobicContact CG1-CD2 4.13Å; V455-Y477 HydrophobicContact CG1-CE1 4.37Å; V455-Y477 HydrophobicContact CG1-CE2 3.57Å
456	S	91.6	Very high	89.3	Confident	4 Å²	4	9.9 Å²	9.9	3%	0.028	5%	0.05	C	C	.	.	H	α-helix	trans	-58.1	-43.9	-178.9	-164.7	0	0	0	0	111	Q223 K452 T453 V459 G460 Y474	Q223-S456 PolarHBondContact OE1-OG 3.15Å; K452-S456 PolarHBondContact O-N 2.85Å; T453-S456 PolarHBondContact O-N 3.14Å; S456-V459 PolarHBondContact O-N 2.96Å; S456-G460 PolarHBondContact O-N 2.94Å; S456-Y474 PolarHBondContact O-OH 3.39Å
457	T	91.1	Very high	88.3	Confident	0 Å²	0	10.5 Å²	10.5	0%	0	5%	0.051	C	C	.	.	H	α-helix	trans	-63.7	-49.3	175.8	-56.2	0	0	0	0	111.7	I220 L398 T453 G454 V455 V459 G460 L461	I220-T457 HydrophobicContact CB-CG2 4.28Å; I220-T457 HydrophobicContact CG1-CG2 3.55Å; L398-T457 HydrophobicContact CD2-CG2 4.26Å; T453-T457 WeakPolarHBondContact O-CB 3.48Å; T453-T457 PolarHBondContact O-N 3.39Å; T453-T457 PolarHBondContact O-OG1 3.49Å; G454-T457 PolarHBondContact O-N 2.98Å; V455-T457 VanDerWaalsContact C-N 3.27Å; V455-T457 PolarHBondContact O-N 3.3Å; T457-V459 VanDerWaalsContact C-N 3.31Å; T457-V459 PolarHBondContact O-N 3.38Å; T457-G460 PolarHBondContact O-N 3.05Å; T457-L461 HydrophobicContact CG2-CD1 3.82Å; T457-L461 HydrophobicContact CG2-CG 4.18Å; T457-L461 WeakPolarHBondContact O-CB 3.4Å; T457-L461 WeakPolarHBondContact O-CG 3.48Å; T457-L461 PolarHBondContact O-N 3.49Å
458	V	90.8	Very high	87.4	Confident	1 Å²	1	14.8 Å²	14.8	1%	0.006	7%	0.071	C	C	.	.	H	α-helix	trans	-57.4	-44.2	178.2	169.3	0	0	0	0	111.3	L345 R403 G454 V455 L461 L462 Y514	L345-V458 HydrophobicContact CD2-CG1 4.37Å; R403-V458 HydrophobicContact CG-CG2 3.65Å; G454-V458 WeakPolarHBondContact O-CB 3.47Å; G454-V458 WeakPolarHBondContact O-CG2 3.39Å; G454-V458 PolarHBondContact O-N 3.21Å; V455-V458 PolarHBondContact O-N 3.26Å; V458-L461 PolarHBondContact O-N 2.91Å; V458-L462 HydrophobicContact CG1-CD1 3.76Å; V458-L462 HydrophobicContact CG1-CG 4.34Å; V458-L462 WeakPolarHBondContact O-CB 3.33Å; V458-L462 VanDerWaalsContact O-CG 3.28Å; V458-L462 WeakPolarHBondContact O-CG 3.31Å; V458-L462 PolarHBondContact O-N 3.09Å; V458-Y514 HydrophobicContact CG1-CE2 4.44Å
459	V	91	Very high	86.7	Confident	0 Å²	0	16 Å²	16	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-62	-50.3	176.2	166	0	0	0	0	110.7	F349 V455 S456 T457 L461 L462 Y463 V473 Y474	F349-V459 HydrophobicContact CE1-CG2 3.99Å; F349-V459 HydrophobicContact CZ-CG2 4.05Å; V455-V459 HydrophobicContact CG1-CG2 4.31Å; V455-V459 WeakPolarHBondContact O-CB 3.5Å; V455-V459 WeakPolarHBondContact O-CG2 3.27Å; V455-V459 PolarHBondContact O-N 2.87Å; S456-V459 PolarHBondContact O-N 2.96Å; T457-V459 VanDerWaalsContact C-N 3.31Å; T457-V459 PolarHBondContact O-N 3.38Å; V459-L461 VanDerWaalsContact C-N 3.3Å; V459-L461 PolarHBondContact O-N 3Å; V459-L462 PolarHBondContact O-N 2.95Å; V459-Y463 PolarHBondContact O-N 2.94Å; V459-V473 HydrophobicContact CG1-CG1 3.58Å; V459-Y474 HydrophobicContact CG1-CE1 4.27Å; V459-Y474 HydrophobicContact CG1-CE2 4.25Å
460	G	88.9	Confident	86.3	Confident	0 Å²	0	16 Å²	16	0%	0	8%	0.075	C	C	.	.	H	α-helix	trans	-59.9	-36.7	177	0	0	0	0	0	113.5	S456 T457 A464	S456-G460 PolarHBondContact O-N 2.94Å; T457-G460 PolarHBondContact O-N 3.05Å; G460-A464 WeakPolarHBondContact O-CA 3.25Å; G460-A464 WeakPolarHBondContact O-CB 3.37Å; G460-A464 PolarHBondContact O-N 3.13Å; G460-A464 VanDerWaalsContact O-N 3.11Å
461	L	89	Confident	86	Confident	9 Å²	9	15.5 Å²	15.5	5%	0.047	7%	0.072	C	C	.	.	H	α-helix	trans	-71.8	-39.9	176.7	-67.3	172	0	0	0	112.9	Y216 I219 I220 T457 V458 V459 Y463	Y216-L461 VanDerWaalsContact CB-CD2 3.43Å; Y216-L461 HydrophobicContact CD1-CB 4.44Å; Y216-L461 HydrophobicContact CD1-CD2 3.32Å; Y216-L461 HydrophobicContact CD1-CG 4.47Å; Y216-L461 HydrophobicContact CD2-CD2 4.07Å; Y216-L461 HydrophobicContact CE1-CB 4.28Å; Y216-L461 HydrophobicContact CE1-CD2 4Å; Y216-L461 VanDerWaalsContact CE1-O 3.28Å; Y216-L461 WeakPolarHBondContact CE1-O 3.26Å; Y216-L461 HydrophobicContact CG-CD2 3.35Å; Y216-L461 PolarHBondContact OH-O 2.97Å; I219-L461 HydrophobicContact CB-CD2 4.5Å; I220-L461 HydrophobicContact CD1-CD2 4.46Å; I220-L461 HydrophobicContact CG1-CD1 4.36Å; I220-L461 HydrophobicContact CG1-CD2 4.32Å; T457-L461 HydrophobicContact CG2-CD1 3.82Å; T457-L461 HydrophobicContact CG2-CG 4.18Å; T457-L461 WeakPolarHBondContact O-CB 3.4Å; T457-L461 WeakPolarHBondContact O-CG 3.48Å; T457-L461 PolarHBondContact O-N 3.49Å; V458-L461 PolarHBondContact O-N 2.91Å; V459-L461 VanDerWaalsContact C-N 3.3Å; V459-L461 PolarHBondContact O-N 3Å; L461-Y463 VanDerWaalsContact C-N 3.34Å
462	L	87.3	Confident	85.7	Confident	17 Å²	17	15.6 Å²	15.6	9%	0.089	7%	0.073	C	C	.	.	H	α-helix	trans	-72.1	-25.7	-176.9	-78.4	173.2	0	0	0	113.9	R341 L345 V458 V459 M517	R341-L462 PolarHBondContact NH1-O 2.69Å; L345-L462 HydrophobicContact CD1-CD1 3.91Å; V458-L462 HydrophobicContact CG1-CD1 3.76Å; V458-L462 HydrophobicContact CG1-CG 4.34Å; V458-L462 WeakPolarHBondContact O-CB 3.33Å; V458-L462 VanDerWaalsContact O-CG 3.28Å; V458-L462 WeakPolarHBondContact O-CG 3.31Å; V458-L462 PolarHBondContact O-N 3.09Å; V459-L462 PolarHBondContact O-N 2.95Å; L462-M517 HydrophobicContact CD1-CE 4.27Å; L462-M517 HydrophobicContact CD1-SD 4.07Å
463	Y	85.9	Confident	85.8	Confident	1 Å²	1	14.4 Å²	14.4	0%	0.004	7%	0.067	C	C	.	.	T	Hydrogen-bonded Turn	trans	-119.2	21.6	179.7	-62.2	-83.3	0	0	0	112.1	D339 V459 L461 E465 E466 V473	D339-Y463 PolarHBondContact OD2-OH 3.19Å; V459-Y463 PolarHBondContact O-N 2.94Å; L461-Y463 VanDerWaalsContact C-N 3.34Å; Y463-E465 PolarHBondContact O-N 3.39Å; Y463-E466 PolarHBondContact O-N 2.81Å; Y463-V473 HydrophobicContact CD1-CG2 3.99Å; Y463-V473 HydrophobicContact CD2-CB 4.36Å; Y463-V473 HydrophobicContact CD2-CG1 3.76Å; Y463-V473 HydrophobicContact CD2-CG2 3.98Å; Y463-V473 HydrophobicContact CE1-CG2 4Å; Y463-V473 HydrophobicContact CE2-CG1 3.75Å; Y463-V473 HydrophobicContact CE2-CG2 3.99Å; Y463-V473 HydrophobicContact CG-CG1 4.49Å; Y463-V473 HydrophobicContact CG-CG2 3.98Å
464	A	80.6	Confident	85.8	Confident	4 Å²	4	14.4 Å²	14.4	3%	0.033	7%	0.067	C	C	.	.	S	Bend	trans	-63.4	-26.1	176.6	0	0	0	0	0	113	Q191 Y216 I219 G460	Q191-A464 PolarHBondContact NE2-O 3.43Å; Y216-A464 HydrophobicContact CD1-CB 4.4Å; Y216-A464 HydrophobicContact CE1-CB 4.02Å; I219-A464 HydrophobicContact CD1-CB 3.72Å; G460-A464 WeakPolarHBondContact O-CA 3.25Å; G460-A464 WeakPolarHBondContact O-CB 3.37Å; G460-A464 PolarHBondContact O-N 3.13Å; G460-A464 VanDerWaalsContact O-N 3.11Å
465	E	74.6	Confident	85.9	Confident	60 Å²	60	14.3 Å²	14.3	28%	0.28	7%	0.067	S	C	.	.	S	Bend	trans	-79.9	-32.5	179.9	-65.5	176.8	-144.9	0	0	111.4	K212 Y463	K212-E465 WeakPolarHBondContact CG-OE1 3.37Å; K212-E465 VanDerWaalsContact NZ-CD 3.3Å; K212-E465 IonicContact NZ-OE1 3.08Å; K212-E465 PolarHBondContact NZ-OE1 2.96Å; K212-E465 VanDerWaalsContact NZ-OE1 3.08Å; K212-E465 IonicContact NZ-OE2 2.67Å; K212-E465 PolarHBondContact NZ-OE2 3.47Å; Y463-E465 PolarHBondContact O-N 3.39Å
466	E	76.5	Confident	86	Confident	38 Å²	38	14.3 Å²	14.3	18%	0.178	7%	0.067	C	C	.	.			trans	-106.4	72.5	-175.2	-54.8	90.8	174.3	0	0	113.3	Y463 E468 R469	Y463-E466 PolarHBondContact O-N 2.81Å; E466-E468 PolarHBondContact O-N 3.44Å; E466-E468 VanDerWaalsContact O-N 3.08Å; E466-R469 HydrophobicContact CB-CB 4.04Å; E466-R469 HydrophobicContact CB-CG 3.92Å; E466-R469 PolarHBondContact O-N 3.32Å
467	K	74.3	Confident	86.1	Confident	41 Å²	41	14.2 Å²	14.2	18%	0.178	7%	0.066	C	C	.	.	G	3₁₀ helix	trans	-37.7	-50.6	176.5	-63.7	169.7	172.6	-177.4	0	113.5	E195 R469 L470	E195-K467 WeakPolarHBondContact OE1-CE 3.47Å; E195-K467 IonicContact OE1-NZ 3.76Å; E195-K467 PolarHBondContact OE1-NZ 2.91Å; K467-R469 VanDerWaalsContact C-N 3.26Å; K467-R469 PolarHBondContact O-N 3.28Å; K467-L470 VanDerWaalsContact O-CB 3.3Å; K467-L470 WeakPolarHBondContact O-CB 3.27Å; K467-L470 PolarHBondContact O-N 2.98Å
468	E	74.8	Confident	86.2	Confident	90 Å²	90	14.8 Å²	14.8	42%	0.421	7%	0.069	S	C	.	.	G	3₁₀ helix	trans	-67.6	-17	-176.3	-47.6	176.8	-179.9	0	0	115	R134 L321 E466 I532	R134-E468 PolarHBondContact NH2-O 3.21Å; L321-E468 HydrophobicContact CD2-CB 3.87Å; L321-E468 HydrophobicContact CD2-CG 3.88Å; E466-E468 PolarHBondContact O-N 3.44Å; E466-E468 VanDerWaalsContact O-N 3.08Å; E468-I532 HydrophobicContact CB-CD1 4.31Å
469	R	81.3	Confident	86.4	Confident	31 Å²	31	16.6 Å²	16.6	12%	0.117	8%	0.075	C	C	.	.	G	3₁₀ helix	trans	-94.2	-17	-176.1	-65.4	178.8	-168.1	-102.2	0.4	113	H336 E466 K467 D471 F472 V473 P530 I532	H336-R469 WeakPolarHBondContact NE2-CD 3.25Å; H336-R469 PolarHBondContact NE2-NH1 3.38Å; E466-R469 HydrophobicContact CB-CB 4.04Å; E466-R469 HydrophobicContact CB-CG 3.92Å; E466-R469 PolarHBondContact O-N 3.32Å; K467-R469 VanDerWaalsContact C-N 3.26Å; K467-R469 PolarHBondContact O-N 3.28Å; R469-D471 VanDerWaalsContact C-N 3.31Å; R469-D471 PolarHBondContact O-N 3.26Å; R469-F472 PolarHBondContact O-N 3.02Å; R469-F472 VanDerWaalsContact O-N 3.1Å; R469-V473 PolarHBondContact O-N 3.01Å; R469-V473 VanDerWaalsContact O-N 3.15Å; R469-P530 VanDerWaalsContact CZ-O 3.29Å; R469-P530 PolarHBondContact NH1-O 3.14Å; R469-P530 PolarHBondContact NH2-O 3.3Å; R469-I532 HydrophobicContact CG-CD1 3.77Å
470	L	85	Confident	86.6	Confident	0 Å²	0	19.5 Å²	19.5	0%	0	9%	0.086	C	C	.	.	H	α-helix	trans	-53.3	-46.4	-172.1	-161.2	63	0	0	0	112.2	T187 R188 K467 F472 V473 Y474	T187-L470 HydrophobicContact CG2-CD1 3.99Å; T187-L470 HydrophobicContact CG2-CD2 4Å; R188-L470 HydrophobicContact CB-CD2 4.49Å; K467-L470 VanDerWaalsContact O-CB 3.3Å; K467-L470 WeakPolarHBondContact O-CB 3.27Å; K467-L470 PolarHBondContact O-N 2.98Å; L470-F472 PolarHBondContact O-N 3.41Å; L470-V473 PolarHBondContact O-N 3.35Å; L470-Y474 HydrophobicContact CD1-CD2 4.07Å; L470-Y474 HydrophobicContact CD1-CE2 3.71Å; L470-Y474 HydrophobicContact CG-CD2 3.97Å; L470-Y474 HydrophobicContact CG-CE2 3.96Å; L470-Y474 WeakPolarHBondContact O-CD2 3.4Å; L470-Y474 PolarHBondContact O-N 2.96Å
471	D	85.4	Confident	86.8	Confident	3 Å²	3	20.1 Å²	20.1	2%	0.016	9%	0.089	C	C	.	.	H	α-helix	trans	-59.6	-42.6	179.7	-50	-35.4	0	0	0	112.5	I133 R134 I138 S184 Y313 R469 T475	I133-D471 HydrophobicContact CG2-CB 4.28Å; R134-D471 IonicContact CZ-OD2 3.6Å; R134-D471 IonicContact NE-OD2 3.96Å; R134-D471 PolarHBondContact NE-OD2 3.24Å; R134-D471 IonicContact NH2-OD2 3.21Å; R134-D471 PolarHBondContact NH2-OD2 3.09Å; I138-D471 WeakPolarHBondContact CD1-OD1 3.4Å; S184-D471 WeakPolarHBondContact CB-OD1 3.36Å; S184-D471 WeakPolarHBondContact OG-CA 3.23Å; S184-D471 PolarHBondContact OG-OD1 2.94Å; Y313-D471 PolarHBondContact OH-OD1 3.28Å; Y313-D471 PolarHBondContact OH-OD2 3.21Å; R469-D471 VanDerWaalsContact C-N 3.31Å; R469-D471 PolarHBondContact O-N 3.26Å; D471-T475 VanDerWaalsContact O-CB 3.28Å; D471-T475 WeakPolarHBondContact O-CB 3.19Å; D471-T475 PolarHBondContact O-N 3.42Å; D471-T475 PolarHBondContact O-OG1 3.49Å
472	F	88.4	Confident	87	Confident	2 Å²	2	20.1 Å²	20.1	1%	0.009	9%	0.091	C	C	.	.	H	α-helix	trans	-67.9	-39.9	178.9	-57.6	-61.8	0	0	0	111.2	P130 I329 L332 P333 R469 L470 T475 I476	P130-F472 HydrophobicContact CB-CD1 3.95Å; P130-F472 HydrophobicContact CB-CE1 3.86Å; I329-F472 HydrophobicContact CG2-CE1 4.33Å; L332-F472 HydrophobicContact CB-CE1 4.24Å; L332-F472 HydrophobicContact CB-CE2 4.44Å; L332-F472 HydrophobicContact CB-CZ 4.13Å; L332-F472 HydrophobicContact CD1-CE2 4.37Å; L332-F472 HydrophobicContact CD1-CZ 4.08Å; P333-F472 HydrophobicContact CG-CD1 3.97Å; R469-F472 PolarHBondContact O-N 3.02Å; R469-F472 VanDerWaalsContact O-N 3.1Å; L470-F472 PolarHBondContact O-N 3.41Å; F472-T475 PolarHBondContact O-N 2.85Å; F472-I476 VanDerWaalsContact O-CG1 3.3Å; F472-I476 WeakPolarHBondContact O-CG1 3.29Å; F472-I476 PolarHBondContact O-N 2.97Å
473	V	91.1	Very high	87.3	Confident	0 Å²	0	21 Å²	21	0%	0	10%	0.095	C	C	.	.	H	α-helix	trans	-68.5	-46.3	-179.9	179.1	0	0	0	0	111.3	L342 V459 Y463 R469 L470 T475 I476 Y477	L342-V473 HydrophobicContact CD1-CG1 4.01Å; V459-V473 HydrophobicContact CG1-CG1 3.58Å; Y463-V473 HydrophobicContact CD1-CG2 3.99Å; Y463-V473 HydrophobicContact CD2-CB 4.36Å; Y463-V473 HydrophobicContact CD2-CG1 3.76Å; Y463-V473 HydrophobicContact CD2-CG2 3.98Å; Y463-V473 HydrophobicContact CE1-CG2 4Å; Y463-V473 HydrophobicContact CE2-CG1 3.75Å; Y463-V473 HydrophobicContact CE2-CG2 3.99Å; Y463-V473 HydrophobicContact CG-CG1 4.49Å; Y463-V473 HydrophobicContact CG-CG2 3.98Å; R469-V473 PolarHBondContact O-N 3.01Å; R469-V473 VanDerWaalsContact O-N 3.15Å; L470-V473 PolarHBondContact O-N 3.35Å; V473-T475 VanDerWaalsContact C-N 3.31Å; V473-T475 PolarHBondContact O-N 3.45Å; V473-I476 PolarHBondContact O-N 3.1Å; V473-Y477 WeakPolarHBondContact O-CB 3.15Å; V473-Y477 PolarHBondContact O-N 3.06Å
474	Y	92.3	Very high	87.7	Confident	0 Å²	0	21 Å²	21	0%	0	10%	0.095	C	C	.	.	H	α-helix	trans	-64.8	-35.1	174.4	-85.1	-73.9	0	0	0	112.1	G183 T187 Q223 S456 V459 L470 Y477 H478	G183-Y474 WeakPolarHBondContact O-CE2 3.35Å; T187-Y474 PolarHBondContact OG1-OH 2.91Å; Q223-Y474 PolarHBondContact NE2-OH 3.48Å; S456-Y474 PolarHBondContact O-OH 3.39Å; V459-Y474 HydrophobicContact CG1-CE1 4.27Å; V459-Y474 HydrophobicContact CG1-CE2 4.25Å; L470-Y474 HydrophobicContact CD1-CD2 4.07Å; L470-Y474 HydrophobicContact CD1-CE2 3.71Å; L470-Y474 HydrophobicContact CG-CD2 3.97Å; L470-Y474 HydrophobicContact CG-CE2 3.96Å; L470-Y474 WeakPolarHBondContact O-CD2 3.4Å; L470-Y474 PolarHBondContact O-N 2.96Å; Y474-Y477 AromaticContact CD1-CD1 3.97Å; Y474-Y477 HydrophobicContact CD1-CD1 3.97Å; Y474-Y477 HydrophobicContact CE1-CD1 4.35Å; Y474-Y477 PolarHBondContact O-N 2.7Å; Y474-H478 AromaticContact CD1-NE2 3.98Å; Y474-H478 PolarHBondContact O-CD2 3.36Å; Y474-H478 PolarHBondContact O-N 3.41Å
475	T	92.7	Very high	88.2	Confident	0 Å²	0	22.6 Å²	22.6	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-60.5	-47.6	172.2	-60.2	0	0	0	0	111.5	L126 T129 P130 D471 F472 V473 H478 W479	L126-T475 HydrophobicContact CD1-CG2 4.05Å; T129-T475 HydrophobicContact CG2-CG2 3.6Å; P130-T475 HydrophobicContact CG-CG2 4.14Å; D471-T475 VanDerWaalsContact O-CB 3.28Å; D471-T475 WeakPolarHBondContact O-CB 3.19Å; D471-T475 PolarHBondContact O-N 3.42Å; D471-T475 PolarHBondContact O-OG1 3.49Å; F472-T475 PolarHBondContact O-N 2.85Å; V473-T475 VanDerWaalsContact C-N 3.31Å; V473-T475 PolarHBondContact O-N 3.45Å; T475-H478 PolarHBondContact O-N 2.91Å; T475-W479 WeakPolarHBondContact O-CB 3.38Å; T475-W479 PolarHBondContact O-N 2.91Å
476	I	93	Very high	89.1	Confident	0 Å²	0	21.7 Å²	21.7	0%	0	10%	0.098	C	C	.	.	H	α-helix	trans	-64.6	-41.9	179	-69.3	163.6	0	0	0	111	L126 P333 H336 L337 L342 F472 V473 W479 W480	L126-I476 HydrophobicContact CD1-CG1 3.98Å; P333-I476 HydrophobicContact CB-CD1 4.22Å; P333-I476 HydrophobicContact CB-CG1 4.43Å; P333-I476 WeakPolarHBondContact O-CD1 3.18Å; H336-I476 HydrophobicContact CB-CD1 4.23Å; L337-I476 HydrophobicContact CD2-CD1 4.25Å; L337-I476 HydrophobicContact CD2-CG2 3.74Å; L337-I476 HydrophobicContact CG-CD1 4.42Å; L342-I476 HydrophobicContact CD1-CG2 4.28Å; L342-I476 HydrophobicContact CD2-CB 4.28Å; L342-I476 HydrophobicContact CD2-CD1 3.63Å; L342-I476 HydrophobicContact CD2-CG2 3.89Å; L342-I476 HydrophobicContact CG-CG2 4.14Å; F472-I476 VanDerWaalsContact O-CG1 3.3Å; F472-I476 WeakPolarHBondContact O-CG1 3.29Å; F472-I476 PolarHBondContact O-N 2.97Å; V473-I476 PolarHBondContact O-N 3.1Å; I476-W479 PolarHBondContact O-N 2.86Å; I476-W480 PolarHBondContact O-N 3.47Å
477	Y	93.3	Very high	89.8	Confident	1 Å²	1	21.6 Å²	21.6	0%	0.004	10%	0.1	C	C	.	.	H	α-helix	trans	-56.2	-53.6	175.3	165.8	-140.6	0	0	0	112.1	F349 V455 V473 Y474 W480 Q481	F349-Y477 HydrophobicContact CB-CD2 3.98Å; F349-Y477 HydrophobicContact CB-CE2 4.47Å; F349-Y477 AromaticContact CD1-CD2 3.28Å; F349-Y477 HydrophobicContact CD1-CD2 3.28Å; F349-Y477 AromaticContact CD1-CE2 3.78Å; F349-Y477 HydrophobicContact CD1-CE2 3.78Å; F349-Y477 HydrophobicContact CD1-CG 4.2Å; F349-Y477 HydrophobicContact CD2-CD2 4.18Å; F349-Y477 AromaticContact CE1-CD2 3.64Å; F349-Y477 HydrophobicContact CE1-CD2 3.64Å; F349-Y477 HydrophobicContact CE1-CE2 4.3Å; F349-Y477 HydrophobicContact CE1-CG 4.14Å; F349-Y477 HydrophobicContact CE2-CD2 4.49Å; F349-Y477 AromaticContact CG-CD2 3.57Å; F349-Y477 HydrophobicContact CG-CD2 3.57Å; F349-Y477 HydrophobicContact CG-CE2 4.31Å; F349-Y477 HydrophobicContact CG-CG 4.49Å; F349-Y477 HydrophobicContact CZ-CD2 4.24Å; F349-Y477 HydrophobicContact CZ-CG 4.4Å; V455-Y477 HydrophobicContact CG1-CD2 4.13Å; V455-Y477 HydrophobicContact CG1-CE1 4.37Å; V455-Y477 HydrophobicContact CG1-CE2 3.57Å; V473-Y477 WeakPolarHBondContact O-CB 3.15Å; V473-Y477 PolarHBondContact O-N 3.06Å; Y474-Y477 AromaticContact CD1-CD1 3.97Å; Y474-Y477 HydrophobicContact CD1-CD1 3.97Å; Y474-Y477 HydrophobicContact CE1-CD1 4.35Å; Y474-Y477 PolarHBondContact O-N 2.7Å; Y477-W480 PolarHBondContact O-N 2.99Å; Y477-Q481 HydrophobicContact CD2-CG 4.34Å; Y477-Q481 HydrophobicContact CE2-CG 3.97Å; Y477-Q481 VanDerWaalsContact CZ-NE2 3.31Å; Y477-Q481 PolarHBondContact O-N 3.16Å; Y477-Q481 VanDerWaalsContact O-N 3.12Å; Y477-Q481 PolarHBondContact OH-NE2 3.08Å
478	H	94.2	Very high	90.5	Very high	13 Å²	13	21.3 Å²	21.3	6%	0.06	10%	0.101	C	C	.	.	H	α-helix	trans	-74.3	-26.7	-177.5	-68.7	-58.7	0	0	0	113.4	V176 W179 Y474 T475 Q481 A482	V176-H478 HydrophobicContact CG1-CB 4.28Å; W179-H478 VanDerWaalsContact C-CD2 3.43Å; W179-H478 HydrophobicContact CB-CB 4.15Å; W179-H478 PolarHBondContact O-NE2 3.24Å; Y474-H478 AromaticContact CD1-NE2 3.98Å; Y474-H478 PolarHBondContact O-CD2 3.36Å; Y474-H478 PolarHBondContact O-N 3.41Å; T475-H478 PolarHBondContact O-N 2.91Å; H478-Q481 PolarHBondContact ND1-OE1 3.14Å; H478-Q481 PolarHBondContact O-N 3.41Å; H478-A482 WeakPolarHBondContact O-CB 3.4Å; H478-A482 PolarHBondContact O-N 3.28Å
479	W	94.5	Very high	91	Very high	39 Å²	39	19.9 Å²	19.9	15%	0.148	9%	0.093	C	C	.	.	H	α-helix	trans	-65.4	-43.7	170	178.6	70.4	0	0	0	112.3	I123 L126 V176 T475 I476 Q481 A482 I483	I123-W479 PolarHBondContact O-NE1 3.41Å; L126-W479 HydrophobicContact CB-CD2 3.88Å; L126-W479 HydrophobicContact CB-CG 3.88Å; L126-W479 HydrophobicContact CB-CZ2 4.28Å; L126-W479 HydrophobicContact CD2-CD2 3.94Å; L126-W479 HydrophobicContact CD2-CE3 3.91Å; L126-W479 HydrophobicContact CD2-CH2 3.84Å; L126-W479 HydrophobicContact CD2-CZ2 3.88Å; L126-W479 HydrophobicContact CD2-CZ3 3.86Å; L126-W479 HydrophobicContact CG-CD2 4.34Å; V176-W479 HydrophobicContact CG1-CB 4.4Å; T475-W479 WeakPolarHBondContact O-CB 3.38Å; T475-W479 PolarHBondContact O-N 2.91Å; I476-W479 PolarHBondContact O-N 2.86Å; W479-Q481 VanDerWaalsContact C-N 3.34Å; W479-Q481 PolarHBondContact O-N 3.39Å; W479-A482 WeakPolarHBondContact O-CB 3.29Å; W479-A482 PolarHBondContact O-N 3.38Å; W479-A482 VanDerWaalsContact O-N 3.14Å; W479-I483 HydrophobicContact CD2-CD1 3.8Å; W479-I483 HydrophobicContact CE3-CD1 3.92Å; W479-I483 HydrophobicContact CH2-CD1 3.78Å; W479-I483 HydrophobicContact CZ2-CD1 3.63Å; W479-I483 HydrophobicContact CZ3-CD1 3.9Å; W479-I483 WeakPolarHBondContact O-CG1 3.24Å; W479-I483 PolarHBondContact O-N 2.93Å
480	W	94.8	Very high	91.3	Very high	61 Å²	61	23.3 Å²	23.3	23%	0.231	11%	0.112	C	C	.	.	H	α-helix	trans	-64.4	-36	173.4	-80.9	112.4	0	0	0	112.9	C346 F349 I350 I476 Y477 I483 A484	C346-W480 HydrophobicContact CB-CD2 4.4Å; C346-W480 HydrophobicContact CB-CZ2 4.5Å; C346-W480 PolarHBondContact SG-NE1 2.94Å; F349-W480 HydrophobicContact CB-CB 3.7Å; F349-W480 HydrophobicContact CD2-CB 4.16Å; F349-W480 HydrophobicContact CD2-CG 4.36Å; F349-W480 HydrophobicContact CG-CB 4.47Å; I350-W480 HydrophobicContact CD1-CE3 3.68Å; I350-W480 HydrophobicContact CD1-CZ3 3.83Å; I350-W480 HydrophobicContact CG1-CD2 4.47Å; I350-W480 HydrophobicContact CG1-CE3 3.74Å; I350-W480 HydrophobicContact CG1-CZ3 4.38Å; I476-W480 PolarHBondContact O-N 3.47Å; Y477-W480 PolarHBondContact O-N 2.99Å; W480-I483 HydrophobicContact CD2-CD1 4.46Å; W480-I483 HydrophobicContact CE3-CD1 3.95Å; W480-I483 HydrophobicContact CZ3-CD1 4.19Å; W480-A484 PolarHBondContact O-N 3Å; W480-A484 VanDerWaalsContact O-N 3.1Å
481	Q	94	Very high	91.3	Very high	13 Å²	13	28.6 Å²	28.6	6%	0.061	13%	0.132	C	C	.	.	H	α-helix	trans	-62.7	-41.6	170	-79.7	-179.5	-25.9	0	0	111.9	F349 S352 Y477 H478 W479 A484 I485	F349-Q481 VanDerWaalsContact O-CG 3.28Å; F349-Q481 WeakPolarHBondContact O-CG 3.5Å; S352-Q481 PolarHBondContact OG-NE2 3.4Å; Y477-Q481 HydrophobicContact CD2-CG 4.34Å; Y477-Q481 HydrophobicContact CE2-CG 3.97Å; Y477-Q481 VanDerWaalsContact CZ-NE2 3.31Å; Y477-Q481 PolarHBondContact O-N 3.16Å; Y477-Q481 VanDerWaalsContact O-N 3.12Å; Y477-Q481 PolarHBondContact OH-NE2 3.08Å; H478-Q481 PolarHBondContact ND1-OE1 3.14Å; H478-Q481 PolarHBondContact O-N 3.41Å; W479-Q481 VanDerWaalsContact C-N 3.34Å; W479-Q481 PolarHBondContact O-N 3.39Å; Q481-A484 WeakPolarHBondContact O-CB 3.16Å; Q481-A484 PolarHBondContact O-N 3.45Å; Q481-I485 WeakPolarHBondContact O-CG1 3.41Å; Q481-I485 PolarHBondContact O-N 2.72Å
482	A	93.2	Very high	91	Very high	9 Å²	9	30.8 Å²	30.8	7%	0.074	15%	0.148	C	C	.	.	H	α-helix	trans	-66	-39.3	178.2	0	0	0	0	0	112.7	P122 V176 H478 W479 A484 I485 F486	P122-A482 HydrophobicContact CB-CB 3.63Å; V176-A482 HydrophobicContact CG2-CB 3.73Å; H478-A482 WeakPolarHBondContact O-CB 3.4Å; H478-A482 PolarHBondContact O-N 3.28Å; W479-A482 WeakPolarHBondContact O-CB 3.29Å; W479-A482 PolarHBondContact O-N 3.38Å; W479-A482 VanDerWaalsContact O-N 3.14Å; A482-A484 VanDerWaalsContact C-N 3.3Å; A482-A484 PolarHBondContact O-N 3.27Å; A482-I485 PolarHBondContact O-N 3.38Å; A482-F486 PolarHBondContact O-N 3.3Å
483	I	93.8	Very high	90.8	Very high	36 Å²	36	37.5 Å²	37.5	19%	0.185	18%	0.179	C	C	.	.	H	α-helix	trans	-57.9	-43.9	170.3	-69.7	168.3	0	0	0	110.7	W479 W480 F486 V487	W479-I483 HydrophobicContact CD2-CD1 3.8Å; W479-I483 HydrophobicContact CE3-CD1 3.92Å; W479-I483 HydrophobicContact CH2-CD1 3.78Å; W479-I483 HydrophobicContact CZ2-CD1 3.63Å; W479-I483 HydrophobicContact CZ3-CD1 3.9Å; W479-I483 WeakPolarHBondContact O-CG1 3.24Å; W479-I483 PolarHBondContact O-N 2.93Å; W480-I483 HydrophobicContact CD2-CD1 4.46Å; W480-I483 HydrophobicContact CE3-CD1 3.95Å; W480-I483 HydrophobicContact CZ3-CD1 4.19Å; I483-F486 WeakPolarHBondContact O-CB 3.3Å; I483-F486 PolarHBondContact O-N 3.01Å; I483-V487 HydrophobicContact CG2-CG2 4.42Å; I483-V487 WeakPolarHBondContact O-CG2 3.32Å; I483-V487 PolarHBondContact O-N 2.99Å
484	A	93.9	Very high	90.5	Very high	1 Å²	1	41.1 Å²	41.1	1%	0.008	20%	0.197	C	C	.	.	H	α-helix	trans	-64	-41.4	178.1	0	0	0	0	0	112.8	I350 L354 W480 Q481 A482 F486 V487 V488	I350-A484 HydrophobicContact CB-CB 4.39Å; I350-A484 HydrophobicContact CG2-CB 3.98Å; I350-A484 WeakPolarHBondContact O-CB 3.44Å; L354-A484 HydrophobicContact CD2-CB 3.98Å; L354-A484 HydrophobicContact CG-CB 4.13Å; W480-A484 PolarHBondContact O-N 3Å; W480-A484 VanDerWaalsContact O-N 3.1Å; Q481-A484 WeakPolarHBondContact O-CB 3.16Å; Q481-A484 PolarHBondContact O-N 3.45Å; A482-A484 VanDerWaalsContact C-N 3.3Å; A482-A484 PolarHBondContact O-N 3.27Å; A484-F486 VanDerWaalsContact C-N 3.34Å; A484-F486 PolarHBondContact O-N 3.12Å; A484-V487 PolarHBondContact O-N 2.9Å; A484-V488 WeakPolarHBondContact O-CG2 3.44Å; A484-V488 PolarHBondContact O-N 2.84Å
485	I	91.7	Very high	90.4	Very high	36 Å²	36	43.4 Å²	43.4	19%	0.185	21%	0.212	C	C	.	.	H	α-helix	trans	-59.6	-45.3	174	-67.3	167.5	0	0	0	110.5	N119 L357 Q481 A482 V487 V488 Y489	N119-I485 WeakPolarHBondContact OD1-CG2 3.44Å; L357-I485 HydrophobicContact CD1-CG2 4.23Å; L357-I485 HydrophobicContact CD2-CB 4.48Å; L357-I485 HydrophobicContact CD2-CD1 4.29Å; L357-I485 HydrophobicContact CD2-CG1 3.82Å; L357-I485 HydrophobicContact CD2-CG2 4.09Å; L357-I485 HydrophobicContact CG-CB 4.31Å; L357-I485 HydrophobicContact CG-CG1 4Å; L357-I485 HydrophobicContact CG-CG2 4Å; Q481-I485 WeakPolarHBondContact O-CG1 3.41Å; Q481-I485 PolarHBondContact O-N 2.72Å; A482-I485 PolarHBondContact O-N 3.38Å; I485-V487 PolarHBondContact O-N 2.99Å; I485-V488 PolarHBondContact O-N 3.08Å; I485-Y489 PolarHBondContact O-N 3.44Å; I485-Y489 VanDerWaalsContact O-N 3.08Å
486	F	92.6	Very high	90.2	Very high	42 Å²	42	43.5 Å²	43.5	18%	0.184	21%	0.213	C	C	.	.	H	α-helix	trans	-61.6	-40.4	175.1	172.7	-112.9	0	0	0	113.1	V120 I123 A482 I483 A484 V488 Y489 L490	V120-F486 HydrophobicContact CG2-CD2 4.2Å; V120-F486 HydrophobicContact CG2-CE2 3.78Å; I123-F486 HydrophobicContact CD1-CB 4.46Å; I123-F486 HydrophobicContact CD1-CD1 3.51Å; I123-F486 HydrophobicContact CD1-CD2 3.9Å; I123-F486 HydrophobicContact CD1-CE1 3.53Å; I123-F486 HydrophobicContact CD1-CE2 3.95Å; I123-F486 HydrophobicContact CD1-CG 3.68Å; I123-F486 HydrophobicContact CD1-CZ 3.75Å; I123-F486 HydrophobicContact CG1-CD1 4.18Å; I123-F486 HydrophobicContact CG1-CG 4.22Å; A482-F486 PolarHBondContact O-N 3.3Å; I483-F486 WeakPolarHBondContact O-CB 3.3Å; I483-F486 PolarHBondContact O-N 3.01Å; A484-F486 VanDerWaalsContact C-N 3.34Å; A484-F486 PolarHBondContact O-N 3.12Å; F486-V488 PolarHBondContact O-N 3.47Å; F486-Y489 HydrophobicContact CD2-CD1 4.26Å; F486-Y489 HydrophobicContact CE2-CD1 4.36Å; F486-Y489 WeakPolarHBondContact O-CB 3.35Å; F486-Y489 PolarHBondContact O-N 3.09Å; F486-L490 HydrophobicContact CD1-CD1 4.26Å; F486-L490 HydrophobicContact CD2-CG 4.46Å; F486-L490 HydrophobicContact CE1-CD1 3.58Å; F486-L490 HydrophobicContact CE1-CG 4.11Å; F486-L490 HydrophobicContact CE2-CD1 4.28Å; F486-L490 HydrophobicContact CE2-CD2 3.9Å; F486-L490 HydrophobicContact CE2-CG 3.94Å; F486-L490 HydrophobicContact CZ-CD1 3.6Å; F486-L490 HydrophobicContact CZ-CD2 3.82Å; F486-L490 HydrophobicContact CZ-CG 3.77Å; F486-L490 PolarHBondContact O-N 3.25Å
487	V	91.5	Very high	90	Very high	36 Å²	36	50 Å²	50	22%	0.218	24%	0.237	C	C	.	.	H	α-helix	trans	-62.9	-39.8	175.5	167.7	0	0	0	0	111.7	I483 A484 I485 Y489 L490 W491	I483-V487 HydrophobicContact CG2-CG2 4.42Å; I483-V487 WeakPolarHBondContact O-CG2 3.32Å; I483-V487 PolarHBondContact O-N 2.99Å; A484-V487 PolarHBondContact O-N 2.9Å; I485-V487 PolarHBondContact O-N 2.99Å; V487-Y489 VanDerWaalsContact C-N 3.33Å; V487-Y489 PolarHBondContact O-N 3.38Å; V487-L490 PolarHBondContact O-N 3.15Å; V487-W491 HydrophobicContact CG1-CD2 3.96Å; V487-W491 HydrophobicContact CG1-CE3 3.47Å; V487-W491 VanDerWaalsContact CG1-CE3 3.47Å; V487-W491 HydrophobicContact CG1-CH2 3.58Å; V487-W491 HydrophobicContact CG1-CZ2 4.05Å; V487-W491 HydrophobicContact CG1-CZ3 3.25Å; V487-W491 PolarHBondContact O-N 3.48Å
488	V	88.6	Confident	89.9	Confident	34 Å²	34	51.2 Å²	51.2	21%	0.206	25%	0.247	C	C	.	.	H	α-helix	trans	-62.7	-41.5	173.4	177.9	0	0	0	0	111.3	L354 L357 A484 I485 F486 W491 S492	L354-V488 HydrophobicContact CD2-CG2 3.51Å; L357-V488 HydrophobicContact CB-CB 4.3Å; L357-V488 HydrophobicContact CB-CG1 4.14Å; L357-V488 HydrophobicContact CB-CG2 4.16Å; L357-V488 HydrophobicContact CD1-CG1 4.29Å; A484-V488 WeakPolarHBondContact O-CG2 3.44Å; A484-V488 PolarHBondContact O-N 2.84Å; I485-V488 PolarHBondContact O-N 3.08Å; F486-V488 PolarHBondContact O-N 3.47Å; V488-W491 CarbonylContact O-C 3.58Å; V488-W491 PolarHBondContact O-N 3.42Å; V488-S492 PolarHBondContact O-N 3.38Å
489	Y	86.4	Confident	89.7	Confident	61 Å²	61	52.6 Å²	52.6	24%	0.239	25%	0.253	C	S	.	.	H	α-helix	trans	-59.3	-48	176.4	169.3	-101.5	0	0	0	112	L115 N119 I485 F486 V487 W491 S492	L115-Y489 HydrophobicContact CB-CE2 4.41Å; L115-Y489 HydrophobicContact CD2-CD2 4.1Å; L115-Y489 HydrophobicContact CD2-CE2 3.95Å; L115-Y489 HydrophobicContact CG-CD2 4.16Å; L115-Y489 HydrophobicContact CG-CE2 4Å; N119-Y489 HydrophobicContact CB-CD1 4.41Å; N119-Y489 HydrophobicContact CB-CG 4.29Å; I485-Y489 PolarHBondContact O-N 3.44Å; I485-Y489 VanDerWaalsContact O-N 3.08Å; F486-Y489 HydrophobicContact CD2-CD1 4.26Å; F486-Y489 HydrophobicContact CE2-CD1 4.36Å; F486-Y489 WeakPolarHBondContact O-CB 3.35Å; F486-Y489 PolarHBondContact O-N 3.09Å; V487-Y489 VanDerWaalsContact C-N 3.33Å; V487-Y489 PolarHBondContact O-N 3.38Å; Y489-W491 VanDerWaalsContact C-N 3.26Å; Y489-W491 PolarHBondContact O-N 3.01Å; Y489-S492 WeakPolarHBondContact O-CB 3.49Å; Y489-S492 PolarHBondContact O-N 3.47Å
490	L	86.9	Confident	89.5	Confident	102 Å²	102	50.8 Å²	50.8	53%	0.534	25%	0.246	S	C	.	.	H	α-helix	trans	-59.5	-35	176.7	-69.8	-176.9	0	0	0	113.2	F486 V487	F486-L490 HydrophobicContact CD1-CD1 4.26Å; F486-L490 HydrophobicContact CD2-CG 4.46Å; F486-L490 HydrophobicContact CE1-CD1 3.58Å; F486-L490 HydrophobicContact CE1-CG 4.11Å; F486-L490 HydrophobicContact CE2-CD1 4.28Å; F486-L490 HydrophobicContact CE2-CD2 3.9Å; F486-L490 HydrophobicContact CE2-CG 3.94Å; F486-L490 HydrophobicContact CZ-CD1 3.6Å; F486-L490 HydrophobicContact CZ-CD2 3.82Å; F486-L490 HydrophobicContact CZ-CG 3.77Å; F486-L490 PolarHBondContact O-N 3.25Å; V487-L490 PolarHBondContact O-N 3.15Å
491	W	86.1	Confident	89.4	Confident	111 Å²	111	50.8 Å²	50.8	42%	0.42	26%	0.255	S	S	.	.	T	Hydrogen-bonded Turn	trans	-96.7	18.5	-176	-64.1	-16.8	0	0	0	114	V487 V488 Y489 Q493 M494 K499 I502	V487-W491 HydrophobicContact CG1-CD2 3.96Å; V487-W491 HydrophobicContact CG1-CE3 3.47Å; V487-W491 VanDerWaalsContact CG1-CE3 3.47Å; V487-W491 HydrophobicContact CG1-CH2 3.58Å; V487-W491 HydrophobicContact CG1-CZ2 4.05Å; V487-W491 HydrophobicContact CG1-CZ3 3.25Å; V487-W491 PolarHBondContact O-N 3.48Å; V488-W491 CarbonylContact O-C 3.58Å; V488-W491 PolarHBondContact O-N 3.42Å; Y489-W491 VanDerWaalsContact C-N 3.26Å; Y489-W491 PolarHBondContact O-N 3.01Å; W491-Q493 PolarHBondContact O-N 2.85Å; W491-Q493 VanDerWaalsContact O-N 3.14Å; W491-M494 HydrophobicContact CB-CB 4.36Å; W491-M494 HydrophobicContact CB-CG 3.78Å; W491-M494 HydrophobicContact CG-CG 4.15Å; W491-M494 VanDerWaalsContact O-CB 3.3Å; W491-M494 WeakPolarHBondContact O-CB 3.43Å; W491-M494 PolarHBondContact O-N 3.41Å; W491-K499 WeakPolarHBondContact O-CE 3.37Å; W491-I502 HydrophobicContact CE3-CD1 4.14Å; W491-I502 HydrophobicContact CZ3-CD1 4.02Å; W491-I502 HydrophobicContact CZ3-CG2 4.01Å
492	S	79.1	Confident	89.4	Confident	49 Å²	49	52.5 Å²	52.5	34%	0.343	27%	0.265	S	S	.	.	T	Hydrogen-bonded Turn	trans	-52.2	-37.5	178.7	-176.7	0	0	0	0	113.5	V488 Y489 M494 K499	V488-S492 PolarHBondContact O-N 3.38Å; Y489-S492 WeakPolarHBondContact O-CB 3.49Å; Y489-S492 PolarHBondContact O-N 3.47Å; S492-M494 PolarHBondContact O-N 3.41Å; S492-K499 WeakPolarHBondContact O-CE 3.21Å; S492-K499 PolarHBondContact O-NZ 3.3Å
493	Q	82.6	Confident	89.4	Confident	143 Å²	143	52.6 Å²	52.6	67%	0.668	26%	0.264	S	S	*	.	T	Hydrogen-bonded Turn	trans	-81.7	-5.9	179.6	-62.2	-63.5	-5.9	0	0	115.3	G268 W491	G268-Q493 PolarHBondContact N-O 2.94Å; W491-Q493 PolarHBondContact O-N 2.85Å; W491-Q493 VanDerWaalsContact O-N 3.14Å
494	M	86.3	Confident	89.5	Confident	76 Å²	76	52.6 Å²	52.6	37%	0.374	26%	0.264	S	S	.	.	S	Bend	trans	-66.4	151.9	-178.2	-72	-70.4	-82.5	0	0	112.5	G268 W491 S492 A498 K499	G268-M494 PolarHBondContact N-O 2.95Å; W491-M494 HydrophobicContact CB-CB 4.36Å; W491-M494 HydrophobicContact CB-CG 3.78Å; W491-M494 HydrophobicContact CG-CG 4.15Å; W491-M494 VanDerWaalsContact O-CB 3.3Å; W491-M494 WeakPolarHBondContact O-CB 3.43Å; W491-M494 PolarHBondContact O-N 3.41Å; S492-M494 PolarHBondContact O-N 3.41Å; M494-A498 HydrophobicContact CE-CB 4.16Å; M494-K499 HydrophobicContact CB-CG 4.26Å; M494-K499 VanDerWaalsContact O-CE 3.22Å; M494-K499 WeakPolarHBondContact O-CE 3.39Å; M494-K499 PolarHBondContact O-NZ 2.94Å
495	P	89.6	Confident	89.6	Confident	48 Å²	48	55.4 Å²	55.4	31%	0.312	29%	0.287	S	S	.	.	B	Isolated β-bridge	trans	-60.8	142.3	173.9	23.2	-31.2	0	0	0	112	K267 R497 A498 K499	K267-P495 HydrophobicContact CG-CB 4.24Å; P495-R497 VanDerWaalsContact C-N 3.26Å; P495-R497 PolarHBondContact O-N 2.87Å; P495-A498 HydrophobicContact CG-CB 3.81Å; P495-A498 WeakPolarHBondContact O-CB 3.27Å; P495-A498 PolarHBondContact O-N 3.22Å; P495-K499 PolarHBondContact O-N 3.48Å; P495-K499 VanDerWaalsContact O-N 3.12Å
496	M	88.6	Confident	89.7	Confident	2 Å²	2	55.1 Å²	55.1	1%	0.01	29%	0.287	C	S	.	.	H	α-helix	trans	-62.7	-32.9	-174.3	-166.1	57	168.9	0	0	112.5	I266 F358 G362 Y367 A498 K499 L500	I266-M496 HydrophobicContact CB-CB 4.46Å; I266-M496 PolarHBondContact O-N 3.46Å; F358-M496 HydrophobicContact CD2-CE 4.3Å; F358-M496 HydrophobicContact CE2-CE 3.39Å; F358-M496 HydrophobicContact CE2-SD 4.41Å; F358-M496 HydrophobicContact CZ-CE 3.86Å; G362-M496 WeakPolarHBondContact O-CE 3.44Å; Y367-M496 HydrophobicContact CD2-CE 4.24Å; Y367-M496 HydrophobicContact CE2-CE 3.71Å; Y367-M496 HydrophobicContact CE2-CG 4.31Å; M496-A498 PolarHBondContact O-N 2.94Å; M496-K499 PolarHBondContact O-N 3.21Å; M496-K499 HydrophobicContact SD-CB 4.24Å; M496-K499 HydrophobicContact SD-CD 3.86Å; M496-L500 HydrophobicContact CG-CD1 4.37Å; M496-L500 WeakPolarHBondContact O-CB 3.48Å; M496-L500 WeakPolarHBondContact O-CG 3.36Å; M496-L500 PolarHBondContact O-N 3.48Å
497	R	88.6	Confident	89.9	Confident	138 Å²	138	53.2 Å²	53.2	52%	0.521	28%	0.279	S	S	.	.	H	α-helix	trans	-57.7	-43.6	169.3	-59.5	-157.7	168.5	158.6	-5.1	112.8	A264 P495 L500 S501	A264-R497 HydrophobicContact CB-CG 4.27Å; A264-R497 WeakPolarHBondContact O-CG 3.34Å; A264-R497 PolarHBondContact O-N 3.41Å; P495-R497 VanDerWaalsContact C-N 3.26Å; P495-R497 PolarHBondContact O-N 2.87Å; R497-L500 PolarHBondContact O-N 3.05Å; R497-S501 WeakPolarHBondContact O-CB 3.18Å; R497-S501 PolarHBondContact O-N 3.43Å; R497-S501 PolarHBondContact O-OG 3.48Å; R497-S501 VanDerWaalsContact O-OG 3.07Å
498	A	90.8	Very high	90.1	Very high	25 Å²	25	56.5 Å²	56.5	21%	0.207	30%	0.295	C	S	.	.	H	α-helix	trans	-67.9	-42.1	179.4	0	0	0	0	0	111.2	M494 P495 M496 L500 S501 I502	M494-A498 HydrophobicContact CE-CB 4.16Å; P495-A498 HydrophobicContact CG-CB 3.81Å; P495-A498 WeakPolarHBondContact O-CB 3.27Å; P495-A498 PolarHBondContact O-N 3.22Å; M496-A498 PolarHBondContact O-N 2.94Å; A498-L500 PolarHBondContact O-N 3.04Å; A498-S501 PolarHBondContact O-N 3.16Å; A498-I502 WeakPolarHBondContact O-CB 3.38Å; A498-I502 WeakPolarHBondContact O-CD1 3.31Å; A498-I502 WeakPolarHBondContact O-CG1 3.45Å; A498-I502 PolarHBondContact O-N 3.34Å
499	K	90.6	Very high	90.4	Very high	43 Å²	43	59.5 Å²	59.5	19%	0.187	31%	0.309	C	S	.	.	H	α-helix	trans	-55	-52.5	173.6	-65.3	175.3	178.8	169.5	0	110.7	W491 S492 M494 P495 M496 S501 I502 L503	W491-K499 WeakPolarHBondContact O-CE 3.37Å; S492-K499 WeakPolarHBondContact O-CE 3.21Å; S492-K499 PolarHBondContact O-NZ 3.3Å; M494-K499 HydrophobicContact CB-CG 4.26Å; M494-K499 VanDerWaalsContact O-CE 3.22Å; M494-K499 WeakPolarHBondContact O-CE 3.39Å; M494-K499 PolarHBondContact O-NZ 2.94Å; P495-K499 PolarHBondContact O-N 3.48Å; P495-K499 VanDerWaalsContact O-N 3.12Å; M496-K499 PolarHBondContact O-N 3.21Å; M496-K499 HydrophobicContact SD-CB 4.24Å; M496-K499 HydrophobicContact SD-CD 3.86Å; K499-S501 PolarHBondContact O-N 3.04Å; K499-I502 PolarHBondContact O-N 2.77Å; K499-L503 WeakPolarHBondContact O-CD1 3.38Å; K499-L503 PolarHBondContact O-N 3.49Å
500	L	91.1	Very high	90.9	Very high	0 Å²	0	56.6 Å²	56.6	0%	0	30%	0.298	C	S	.	.	H	α-helix	trans	-59.8	-45.4	177.4	-76.3	167	0	0	0	113.3	F358 L418 L421 L422 M496 R497 A498 I502 L503 L504	F358-L500 HydrophobicContact CE1-CD2 4.48Å; F358-L500 HydrophobicContact CE2-CD2 3.72Å; F358-L500 HydrophobicContact CE2-CG 4.25Å; F358-L500 HydrophobicContact CZ-CD2 3.48Å; F358-L500 VanDerWaalsContact CZ-CD2 3.48Å; F358-L500 HydrophobicContact CZ-CG 4.4Å; L418-L500 HydrophobicContact CD2-CD2 3.6Å; L421-L500 HydrophobicContact CB-CD1 4.26Å; L421-L500 HydrophobicContact CB-CD2 3.96Å; L421-L500 HydrophobicContact CD1-CD2 4.32Å; L422-L500 HydrophobicContact CD2-CB 3.48Å; L422-L500 VanDerWaalsContact CD2-CB 3.48Å; L422-L500 HydrophobicContact CD2-CD1 3.95Å; L422-L500 HydrophobicContact CD2-CG 4.36Å; L422-L500 HydrophobicContact CG-CB 3.84Å; L422-L500 HydrophobicContact CG-CD1 4.17Å; M496-L500 HydrophobicContact CG-CD1 4.37Å; M496-L500 WeakPolarHBondContact O-CB 3.48Å; M496-L500 WeakPolarHBondContact O-CG 3.36Å; M496-L500 PolarHBondContact O-N 3.48Å; R497-L500 PolarHBondContact O-N 3.05Å; A498-L500 PolarHBondContact O-N 3.04Å; L500-I502 VanDerWaalsContact C-N 3.33Å; L500-I502 PolarHBondContact O-N 3.38Å; L500-L503 PolarHBondContact O-N 2.99Å; L500-L504 PolarHBondContact O-N 3.26Å
501	S	92.4	Very high	91.2	Very high	61 Å²	61	53.1 Å²	53.1	43%	0.427	28%	0.281	S	S	.	.	H	α-helix	trans	-63.6	-36.6	177.5	-65.6	0	0	0	0	112.8	R497 A498 K499 L504 A505	R497-S501 WeakPolarHBondContact O-CB 3.18Å; R497-S501 PolarHBondContact O-N 3.43Å; R497-S501 PolarHBondContact O-OG 3.48Å; R497-S501 VanDerWaalsContact O-OG 3.07Å; A498-S501 PolarHBondContact O-N 3.16Å; K499-S501 PolarHBondContact O-N 3.04Å; S501-L504 PolarHBondContact O-N 3.25Å; S501-A505 WeakPolarHBondContact O-CB 3.46Å; S501-A505 PolarHBondContact O-N 3.32Å
502	I	93.3	Very high	91.6	Very high	50 Å²	50	51.7 Å²	51.7	26%	0.256	29%	0.287	S	S	.	.	H	α-helix	trans	-68.3	-43	175.3	-68.5	163.6	0	0	0	110.7	W491 A498 K499 L500 L504 A505 T506	W491-I502 HydrophobicContact CE3-CD1 4.14Å; W491-I502 HydrophobicContact CZ3-CD1 4.02Å; W491-I502 HydrophobicContact CZ3-CG2 4.01Å; A498-I502 WeakPolarHBondContact O-CB 3.38Å; A498-I502 WeakPolarHBondContact O-CD1 3.31Å; A498-I502 WeakPolarHBondContact O-CG1 3.45Å; A498-I502 PolarHBondContact O-N 3.34Å; K499-I502 PolarHBondContact O-N 2.77Å; L500-I502 VanDerWaalsContact C-N 3.33Å; L500-I502 PolarHBondContact O-N 3.38Å; I502-L504 VanDerWaalsContact C-N 3.32Å; I502-L504 PolarHBondContact O-N 3.24Å; I502-A505 PolarHBondContact O-N 3.08Å; I502-T506 HydrophobicContact CG2-CG2 4.44Å; I502-T506 WeakPolarHBondContact O-CB 3.45Å; I502-T506 WeakPolarHBondContact O-CG2 3.47Å; I502-T506 PolarHBondContact O-N 2.97Å; I502-T506 PolarHBondContact O-OG1 3.27Å
503	L	93.7	Very high	92.4	Very high	10 Å²	10	50.5 Å²	50.5	5%	0.052	28%	0.279	C	S	.	.	H	α-helix	trans	-59.4	-42	172.6	-91	91.2	0	0	0	111.7	L354 F358 L418 K499 L500 T506 L507	L354-L503 HydrophobicContact CB-CG 4.25Å; F358-L503 HydrophobicContact CB-CD1 4.49Å; F358-L503 HydrophobicContact CB-CD2 3.65Å; F358-L503 HydrophobicContact CD1-CD2 4.17Å; F358-L503 HydrophobicContact CD2-CD1 4.06Å; F358-L503 HydrophobicContact CD2-CD2 3.98Å; F358-L503 HydrophobicContact CG-CD1 4.49Å; F358-L503 HydrophobicContact CG-CD2 3.66Å; L418-L503 HydrophobicContact CD1-CB 4.19Å; L418-L503 HydrophobicContact CD2-CB 3.98Å; L418-L503 HydrophobicContact CD2-CD2 4.44Å; K499-L503 WeakPolarHBondContact O-CD1 3.38Å; K499-L503 PolarHBondContact O-N 3.49Å; L500-L503 PolarHBondContact O-N 2.99Å; L503-T506 WeakPolarHBondContact CA-OG1 3.35Å; L503-T506 PolarHBondContact O-OG1 3.18Å; L503-T506 VanDerWaalsContact O-OG1 3.05Å; L503-L507 VanDerWaalsContact O-CB 3.24Å; L503-L507 WeakPolarHBondContact O-CB 3.23Å; L503-L507 PolarHBondContact O-N 3.38Å
504	L	95	Very high	92.9	Very high	37 Å²	37	43.7 Å²	43.7	19%	0.194	25%	0.247	C	C	.	.	H	α-helix	trans	-67.7	-43.2	177.6	-175.2	61.1	0	0	0	112.4	L418 V419 L422 L500 S501 I502 L507 L508	L418-L504 HydrophobicContact CB-CD1 4.29Å; L418-L504 HydrophobicContact CD1-CB 4.26Å; L418-L504 HydrophobicContact CD1-CD1 4.28Å; V419-L504 HydrophobicContact CG2-CD2 4.29Å; L422-L504 HydrophobicContact CD1-CD2 4.13Å; L500-L504 PolarHBondContact O-N 3.26Å; S501-L504 PolarHBondContact O-N 3.25Å; I502-L504 VanDerWaalsContact C-N 3.32Å; I502-L504 PolarHBondContact O-N 3.24Å; L504-L507 WeakPolarHBondContact O-CB 3.2Å; L504-L507 PolarHBondContact O-N 3.21Å; L504-L508 HydrophobicContact CG-CD1 4.35Å; L504-L508 WeakPolarHBondContact O-CG 3.37Å; L504-L508 PolarHBondContact O-N 2.85Å
505	A	95.7	Very high	93.2	Very high	60 Å²	60	45.3 Å²	45.3	50%	0.496	25%	0.249	S	C	.	.	H	α-helix	trans	-64.7	-42.2	178	0	0	0	0	0	112.3	S501 I502 L508 L509	S501-A505 WeakPolarHBondContact O-CB 3.46Å; S501-A505 PolarHBondContact O-N 3.32Å; I502-A505 PolarHBondContact O-N 3.08Å; A505-L508 PolarHBondContact O-N 3.4Å; A505-L509 WeakPolarHBondContact O-CB 3.42Å; A505-L509 PolarHBondContact O-N 3.04Å
506	T	95.3	Very high	93.4	Very high	30 Å²	30	45.8 Å²	45.8	18%	0.184	25%	0.251	C	S	.	.	H	α-helix	trans	-67.8	-36.6	175.8	50	0	0	0	0	112.4	L354 I502 L503 L509 A510	L354-T506 HydrophobicContact CD1-CG2 4.07Å; I502-T506 HydrophobicContact CG2-CG2 4.44Å; I502-T506 WeakPolarHBondContact O-CB 3.45Å; I502-T506 WeakPolarHBondContact O-CG2 3.47Å; I502-T506 PolarHBondContact O-N 2.97Å; I502-T506 PolarHBondContact O-OG1 3.27Å; L503-T506 WeakPolarHBondContact CA-OG1 3.35Å; L503-T506 PolarHBondContact O-OG1 3.18Å; L503-T506 VanDerWaalsContact O-OG1 3.05Å; T506-L509 PolarHBondContact O-N 3.01Å; T506-A510 VanDerWaalsContact O-CB 3.27Å; T506-A510 WeakPolarHBondContact O-CB 3.38Å; T506-A510 PolarHBondContact O-N 3.38Å
507	L	95.8	Very high	93.6	Very high	2 Å²	2	45.7 Å²	45.7	1%	0.01	25%	0.25	C	S	.	.	H	α-helix	trans	-60.7	-48.8	172	179.1	55.1	0	0	0	112.1	Y351 A411 H414 L418 L503 L504 A510 C511	Y351-L507 HydrophobicContact CD1-CD1 4.04Å; Y351-L507 HydrophobicContact CD2-CB 3.88Å; Y351-L507 HydrophobicContact CD2-CD1 4.36Å; Y351-L507 HydrophobicContact CE1-CD1 3.68Å; Y351-L507 HydrophobicContact CE2-CB 3.62Å; Y351-L507 HydrophobicContact CE2-CD1 4.04Å; Y351-L507 HydrophobicContact CE2-CD2 4.34Å; Y351-L507 HydrophobicContact CE2-CG 4.21Å; Y351-L507 HydrophobicContact CG-CD1 4.37Å; A411-L507 HydrophobicContact CB-CD1 3.72Å; H414-L507 HydrophobicContact CB-CD2 4.08Å; L418-L507 HydrophobicContact CD1-CD2 3.89Å; L503-L507 VanDerWaalsContact O-CB 3.24Å; L503-L507 WeakPolarHBondContact O-CB 3.23Å; L503-L507 PolarHBondContact O-N 3.38Å; L504-L507 WeakPolarHBondContact O-CB 3.2Å; L504-L507 PolarHBondContact O-N 3.21Å; L507-A510 PolarHBondContact O-N 2.75Å; L507-C511 PolarHBondContact O-N 2.91Å; L507-C511 PolarHBondContact O-SG 3.3Å
508	L	95.6	Very high	93.7	Very high	105 Å²	105	40.3 Å²	40.3	55%	0.55	23%	0.231	S	C	.	.	H	α-helix	trans	-62.5	-44.1	178.6	-69.6	172.1	0	0	0	111.3	L504 A505 A510 C511 C512	L504-L508 HydrophobicContact CG-CD1 4.35Å; L504-L508 WeakPolarHBondContact O-CG 3.37Å; L504-L508 PolarHBondContact O-N 2.85Å; A505-L508 PolarHBondContact O-N 3.4Å; L508-A510 PolarHBondContact O-N 3.37Å; L508-C511 PolarHBondContact O-N 3.22Å; L508-C512 PolarHBondContact O-N 2.89Å; L508-C512 PolarHBondContact O-SG 3.37Å; L508-C512 VanDerWaalsContact O-SG 3.35Å
509	L	96.1	Very high	93.7	Very high	97 Å²	97	46.1 Å²	46.1	51%	0.508	25%	0.248	S	C	.	.	H	α-helix	trans	-59	-45.9	173.9	179.1	61.8	0	0	0	111.6	P347 A505 T506 C511 C512 C513	P347-L509 HydrophobicContact CB-CD2 4.44Å; P347-L509 HydrophobicContact CB-CG 4.27Å; A505-L509 WeakPolarHBondContact O-CB 3.42Å; A505-L509 PolarHBondContact O-N 3.04Å; T506-L509 PolarHBondContact O-N 3.01Å; L509-C511 VanDerWaalsContact C-N 3.33Å; L509-C511 PolarHBondContact O-N 3.44Å; L509-C512 PolarHBondContact O-N 2.91Å; L509-C513 WeakPolarHBondContact O-CB 3.38Å; L509-C513 PolarHBondContact O-N 2.78Å; L509-C513 PolarHBondContact O-SG 2.73Å; L509-C513 VanDerWaalsContact O-SG 3.35Å
510	A	95.1	Very high	93.6	Very high	0 Å²	0	49.2 Å²	49.2	0%	0	26%	0.258	C	S	.	.	H	α-helix	trans	-61	-40	177.1	0	0	0	0	0	112.4	P347 F348 T506 L507 L508 Y514	P347-A510 HydrophobicContact CB-CB 4.23Å; F348-A510 HydrophobicContact CB-CB 4.05Å; F348-A510 HydrophobicContact CD2-CB 3.77Å; F348-A510 HydrophobicContact CG-CB 4.18Å; T506-A510 VanDerWaalsContact O-CB 3.27Å; T506-A510 WeakPolarHBondContact O-CB 3.38Å; T506-A510 PolarHBondContact O-N 3.38Å; L507-A510 PolarHBondContact O-N 2.75Å; L508-A510 PolarHBondContact O-N 3.37Å; A510-Y514 WeakPolarHBondContact O-CB 3.34Å; A510-Y514 PolarHBondContact O-N 2.75Å
511	C	94.6	Very high	93.5	Very high	28 Å²	28	51.1 Å²	51.1	19%	0.189	27%	0.27	C	S	.	.	H	α-helix	trans	-63.2	-47.2	174.1	-64	0	0	0	0	112	M408 A411 L507 L508 L509 Y514 W515	M408-C511 HydrophobicContact CE-CB 4.09Å; M408-C511 HydrophobicContact SD-CB 4.17Å; A411-C511 VanDerWaalsContact CB-SG 3.6Å; L507-C511 PolarHBondContact O-N 2.91Å; L507-C511 PolarHBondContact O-SG 3.3Å; L508-C511 PolarHBondContact O-N 3.22Å; L509-C511 VanDerWaalsContact C-N 3.33Å; L509-C511 PolarHBondContact O-N 3.44Å; C511-Y514 PolarHBondContact O-N 3.42Å; C511-W515 VanDerWaalsContact O-CB 3.31Å; C511-W515 WeakPolarHBondContact O-CB 3.39Å; C511-W515 PolarHBondContact O-N 3.09Å
512	C	94.9	Very high	93.2	Very high	81 Å²	81	52.1 Å²	52.1	55%	0.547	28%	0.282	S	S	.	.	H	α-helix	trans	-61.4	-46.9	177.8	-68.6	0	0	0	0	112.1	L508 L509 W515 V516	L508-C512 PolarHBondContact O-N 2.89Å; L508-C512 PolarHBondContact O-SG 3.37Å; L508-C512 VanDerWaalsContact O-SG 3.35Å; L509-C512 PolarHBondContact O-N 2.91Å; C512-W515 PolarHBondContact O-N 3.36Å; C512-V516 WeakPolarHBondContact O-CG2 3.25Å; C512-V516 PolarHBondContact O-N 3.27Å
513	C	94.5	Very high	93	Very high	24 Å²	24	56.5 Å²	56.5	16%	0.162	30%	0.301	C	S	.	.	H	α-helix	trans	-64.4	-43.2	178.6	-68.4	0	0	0	0	112.1	L344 P347 L509 V516 M517	L344-C513 HydrophobicContact CB-CB 4.42Å; L344-C513 HydrophobicContact CD2-CB 4.05Å; L344-C513 VanDerWaalsContact O-CB 3.28Å; L344-C513 WeakPolarHBondContact O-CB 3.4Å; P347-C513 HydrophobicContact CG-CB 4.3Å; L509-C513 WeakPolarHBondContact O-CB 3.38Å; L509-C513 PolarHBondContact O-N 2.78Å; L509-C513 PolarHBondContact O-SG 2.73Å; L509-C513 VanDerWaalsContact O-SG 3.35Å; C513-V516 PolarHBondContact O-N 2.9Å; C513-M517 PolarHBondContact O-N 3.48Å
514	Y	93.4	Very high	92.6	Very high	0 Å²	0	64.9 Å²	64.9	0%	0	34%	0.337	C	S	.	.	H	α-helix	trans	-63.3	-43.1	176.7	179.6	-112.2	0	0	0	112.4	L345 W404 L407 M408 V458 A510 C511 V516 M517 E518	L345-Y514 HydrophobicContact CD2-CD2 4.11Å; W404-Y514 VanDerWaalsContact CA-OH 3.31Å; W404-Y514 WeakPolarHBondContact CA-OH 3.39Å; W404-Y514 HydrophobicContact CB-CE1 4.04Å; L407-Y514 HydrophobicContact CB-CD1 4.49Å; L407-Y514 HydrophobicContact CB-CE1 3.86Å; L407-Y514 HydrophobicContact CD2-CD1 3.85Å; L407-Y514 HydrophobicContact CD2-CD2 3.65Å; L407-Y514 HydrophobicContact CD2-CE1 3.76Å; L407-Y514 HydrophobicContact CD2-CE2 3.59Å; L407-Y514 HydrophobicContact CD2-CG 3.79Å; L407-Y514 HydrophobicContact CG-CE1 4.38Å; M408-Y514 HydrophobicContact CE-CD1 3.58Å; M408-Y514 HydrophobicContact CE-CE1 4.28Å; M408-Y514 HydrophobicContact CE-CG 4.41Å; M408-Y514 HydrophobicContact CG-CD1 4.16Å; M408-Y514 HydrophobicContact CG-CE1 4.18Å; M408-Y514 HydrophobicContact SD-CD1 3.89Å; M408-Y514 HydrophobicContact SD-CE1 4.5Å; V458-Y514 HydrophobicContact CG1-CE2 4.44Å; A510-Y514 WeakPolarHBondContact O-CB 3.34Å; A510-Y514 PolarHBondContact O-N 2.75Å; C511-Y514 PolarHBondContact O-N 3.42Å; Y514-V516 PolarHBondContact O-N 3.27Å; Y514-M517 HydrophobicContact CD2-CE 3.77Å; Y514-M517 HydrophobicContact CE2-CE 3.51Å; Y514-M517 WeakPolarHBondContact O-CB 3.48Å; Y514-M517 PolarHBondContact O-N 3.35Å; Y514-M517 VanDerWaalsContact O-N 3.15Å; Y514-E518 HydrophobicContact CD2-CG 4.46Å; Y514-E518 HydrophobicContact CE1-CG 4.01Å; Y514-E518 HydrophobicContact CE2-CG 3.9Å; Y514-E518 WeakPolarHBondContact CE2-OE1 3.43Å; Y514-E518 PolarHBondContact O-N 2.86Å; Y514-E518 PolarHBondContact OH-OE1 3.36Å
515	W	93.2	Very high	92	Very high	110 Å²	110	66 Å²	66	42%	0.417	35%	0.346	S	S	.	.	H	α-helix	trans	-62.1	-40.8	175.5	-177.6	-110.5	0	0	0	112.7	W404 C511 C512 M517 E518 R519	W404-W515 HydrophobicContact CE3-CZ3 4.47Å; C511-W515 VanDerWaalsContact O-CB 3.31Å; C511-W515 WeakPolarHBondContact O-CB 3.39Å; C511-W515 PolarHBondContact O-N 3.09Å; C512-W515 PolarHBondContact O-N 3.36Å; W515-M517 VanDerWaalsContact C-N 3.33Å; W515-E518 PolarHBondContact O-N 2.97Å; W515-R519 VanDerWaalsContact NE1-CZ 3.32Å; W515-R519 VanDerWaalsContact NE1-NE 3.15Å; W515-R519 WeakPolarHBondContact O-CG 3.42Å; W515-R519 PolarHBondContact O-N 3.23Å
516	V	93.6	Very high	91.1	Very high	58 Å²	58	72.3 Å²	72.3	35%	0.352	36%	0.362	S	S	.	.	H	α-helix	trans	-64.7	-37.8	173.3	171.1	0	0	0	0	111.4	L344 C512 C513 Y514 R520	L344-V516 HydrophobicContact CD1-CG1 4.1Å; C512-V516 WeakPolarHBondContact O-CG2 3.25Å; C512-V516 PolarHBondContact O-N 3.27Å; C513-V516 PolarHBondContact O-N 2.9Å; Y514-V516 PolarHBondContact O-N 3.27Å; V516-R520 WeakPolarHBondContact O-CG 3.29Å; V516-R520 PolarHBondContact O-N 3.11Å
517	M	92.3	Very high	90.3	Very high	0 Å²	0	72.7 Å²	72.7	0%	0	37%	0.365	C	S	.	.	H	α-helix	trans	-62.4	-51.6	175.3	-172.2	-153.6	68.4	0	0	111.2	R341 L344 L345 L462 C513 Y514 W515 R519 R520 V521	R341-M517 HydrophobicContact CB-SD 4.5Å; L344-M517 HydrophobicContact CB-CB 3.87Å; L344-M517 HydrophobicContact CB-CG 4.32Å; L344-M517 HydrophobicContact CD1-CB 3.82Å; L344-M517 HydrophobicContact CD1-CG 4.37Å; L345-M517 HydrophobicContact CD1-SD 3.87Å; L345-M517 HydrophobicContact CD2-SD 4.15Å; L345-M517 HydrophobicContact CG-SD 3.75Å; L462-M517 HydrophobicContact CD1-CE 4.27Å; L462-M517 HydrophobicContact CD1-SD 4.07Å; C513-M517 PolarHBondContact O-N 3.48Å; Y514-M517 HydrophobicContact CD2-CE 3.77Å; Y514-M517 HydrophobicContact CE2-CE 3.51Å; Y514-M517 WeakPolarHBondContact O-CB 3.48Å; Y514-M517 PolarHBondContact O-N 3.35Å; Y514-M517 VanDerWaalsContact O-N 3.15Å; W515-M517 VanDerWaalsContact C-N 3.33Å; M517-R519 VanDerWaalsContact C-N 3.29Å; M517-R519 PolarHBondContact O-N 3.2Å; M517-R520 PolarHBondContact O-N 2.95Å; M517-R520 VanDerWaalsContact O-N 3.1Å; M517-V521 HydrophobicContact CG-CG2 4.42Å; M517-V521 WeakPolarHBondContact O-CG2 3.44Å; M517-V521 PolarHBondContact O-N 3.46Å
518	E	90.8	Very high	89.2	Confident	26 Å²	26	82 Å²	82	12%	0.121	40%	0.4	C	S	.	.	H	α-helix	trans	-59.8	-39.3	179.7	-70.3	-65.8	170.9	0	0	111.7	R403 W404 Y514 W515 V521 A522	R403-E518 IonicContact CZ-OE1 2.36Å; R403-E518 IonicContact CZ-OE2 2.7Å; R403-E518 IonicContact NE-OE1 3.51Å; R403-E518 PolarHBondContact NE-OE1 3.05Å; R403-E518 IonicContact NE-OE2 3.5Å; R403-E518 VanDerWaalsContact NH2-CD 3.33Å; R403-E518 IonicContact NH2-OE1 3.42Å; R403-E518 PolarHBondContact NH2-OE1 3.25Å; R403-E518 IonicContact NH2-OE2 3.65Å; R403-E518 PolarHBondContact NH2-OE2 2.93Å; W404-E518 HydrophobicContact CB-CG 4.28Å; Y514-E518 HydrophobicContact CD2-CG 4.46Å; Y514-E518 HydrophobicContact CE1-CG 4.01Å; Y514-E518 HydrophobicContact CE2-CG 3.9Å; Y514-E518 WeakPolarHBondContact CE2-OE1 3.43Å; Y514-E518 PolarHBondContact O-N 2.86Å; Y514-E518 PolarHBondContact OH-OE1 3.36Å; W515-E518 PolarHBondContact O-N 2.97Å; E518-V521 PolarHBondContact O-N 3.31Å; E518-A522 WeakPolarHBondContact O-CB 3.47Å; E518-A522 PolarHBondContact O-N 3.13Å
519	R	90.5	Very high	88	Confident	147 Å²	147	80.4 Å²	80.4	56%	0.555	39%	0.39	S	S	*	.	H	α-helix	trans	-60.5	-45	172.1	-76.4	-175.9	174	-168.9	-0.8	113	W515 M517 A522 Q523	W515-R519 VanDerWaalsContact NE1-CZ 3.32Å; W515-R519 VanDerWaalsContact NE1-NE 3.15Å; W515-R519 WeakPolarHBondContact O-CG 3.42Å; W515-R519 PolarHBondContact O-N 3.23Å; M517-R519 VanDerWaalsContact C-N 3.29Å; M517-R519 PolarHBondContact O-N 3.2Å; R519-A522 PolarHBondContact O-N 3.01Å; R519-Q523 WeakPolarHBondContact O-CB 3.38Å; R519-Q523 VanDerWaalsContact O-CG 3.28Å; R519-Q523 WeakPolarHBondContact O-CG 3.25Å; R519-Q523 PolarHBondContact O-N 2.91Å
520	R	89.8	Confident	86.7	Confident	108 Å²	108	76.8 Å²	76.8	41%	0.408	37%	0.373	S	S	.	.	H	α-helix	trans	-66.9	-35.7	178.3	-72.3	178.7	-178.1	-152.1	0	112.7	Y340 V516 M517 Q523 K524 V525	Y340-R520 HydrophobicContact CD2-CB 4.3Å; Y340-R520 HydrophobicContact CE2-CB 3.67Å; V516-R520 WeakPolarHBondContact O-CG 3.29Å; V516-R520 PolarHBondContact O-N 3.11Å; M517-R520 PolarHBondContact O-N 2.95Å; M517-R520 VanDerWaalsContact O-N 3.1Å; R520-Q523 CarbonylContact O-C 3.58Å; R520-Q523 PolarHBondContact O-N 3.22Å; R520-K524 PolarHBondContact O-N 3.26Å; R520-V525 HydrophobicContact CB-CB 4.48Å; R520-V525 HydrophobicContact CB-CG2 4.35Å; R520-V525 PolarHBondContact O-N 3.38Å; R520-V525 VanDerWaalsContact O-N 3.1Å
521	V	87.6	Confident	85.1	Confident	40 Å²	40	88 Å²	88	24%	0.242	42%	0.415	C	S	.	.	H	α-helix	trans	-68.1	-42.7	174.2	174.2	0	0	0	0	110.8	Y340 M517 E518 Q523 K524	Y340-V521 HydrophobicContact CE2-CG2 4.35Å; M517-V521 HydrophobicContact CG-CG2 4.42Å; M517-V521 WeakPolarHBondContact O-CG2 3.44Å; M517-V521 PolarHBondContact O-N 3.46Å; E518-V521 PolarHBondContact O-N 3.31Å; V521-Q523 VanDerWaalsContact C-N 3.31Å; V521-Q523 PolarHBondContact O-N 3.28Å; V521-K524 WeakPolarHBondContact O-CA 3.39Å; V521-K524 PolarHBondContact O-N 2.97Å
522	A	86.9	Confident	83.7	Confident	82 Å²	82	87.9 Å²	87.9	68%	0.678	41%	0.412	S	S	*	.	H	α-helix	trans	-62.6	-36.5	174	0	0	0	0	0	112.6	E518 R519 K524	E518-A522 WeakPolarHBondContact O-CB 3.47Å; E518-A522 PolarHBondContact O-N 3.13Å; R519-A522 PolarHBondContact O-N 3.01Å; A522-K524 PolarHBondContact O-N 2.68Å
523	Q	88.1	Confident	82.1	Confident	142 Å²	142	86.9 Å²	86.9	66%	0.664	41%	0.405	S	S	*	.	T	Hydrogen-bonded Turn	trans	-72.9	1.6	171.6	-71.9	171.6	-21	0	0	113.9	R519 R520 V521 V525	R519-Q523 WeakPolarHBondContact O-CB 3.38Å; R519-Q523 VanDerWaalsContact O-CG 3.28Å; R519-Q523 WeakPolarHBondContact O-CG 3.25Å; R519-Q523 PolarHBondContact O-N 2.91Å; R520-Q523 CarbonylContact O-C 3.58Å; R520-Q523 PolarHBondContact O-N 3.22Å; V521-Q523 VanDerWaalsContact C-N 3.31Å; V521-Q523 PolarHBondContact O-N 3.28Å; Q523-V525 HydrophobicContact CB-CG2 4.03Å; Q523-V525 PolarHBondContact O-N 3.12Å
524	K	85.1	Confident	80.4	Confident	185 Å²	185	96.8 Å²	96.8	80%	0.804	44%	0.439	S	S	*	.	T	Hydrogen-bonded Turn	trans	54.3	31.5	-179.9	-57.7	-179.1	-178.7	177.2	0	114	R520 V521 A522 K526	R520-K524 PolarHBondContact O-N 3.26Å; V521-K524 WeakPolarHBondContact O-CA 3.39Å; V521-K524 PolarHBondContact O-N 2.97Å; A522-K524 PolarHBondContact O-N 2.68Å; K524-K526 PolarHBondContact O-N 3.43Å
525	V	83.6	Confident	78.7	Confident	62 Å²	62	98.5 Å²	98.5	38%	0.376	45%	0.45	S	S	.	.	P	Polyproline II helix	trans	-62.4	118.6	177.6	179.4	0	0	0	0	109.4	Y340 R520 Q523	Y340-V525 HydrophobicContact CE1-CB 4.39Å; Y340-V525 HydrophobicContact CE1-CG1 4.19Å; Y340-V525 WeakPolarHBondContact CE1-O 3.47Å; Y340-V525 PolarHBondContact OH-O 2.63Å; R520-V525 HydrophobicContact CB-CB 4.48Å; R520-V525 HydrophobicContact CB-CG2 4.35Å; R520-V525 PolarHBondContact O-N 3.38Å; R520-V525 VanDerWaalsContact O-N 3.1Å; Q523-V525 HydrophobicContact CB-CG2 4.03Å; Q523-V525 PolarHBondContact O-N 3.12Å
526	K	77.2	Confident	76.8	Confident	192 Å²	192	102.7 Å²	102.7	84%	0.835	47%	0.466	S	S	*	.	P	Polyproline II helix	trans	-59.8	123.9	-178.7	-69.3	-177.4	179.3	177.8	0	110.4	K524	K524-K526 PolarHBondContact O-N 3.43Å
527	P	77.8	Confident	74.6	Confident	37 Å²	37	106.3 Å²	106.3	24%	0.24	48%	0.478	C	S	.	.	P	Polyproline II helix	trans	-72.2	138.2	175.9	28.7	-32.9	0	0	0	111	D339 Y340 M529	D339-P527 WeakPolarHBondContact OD1-CB 3.34Å; Y340-P527 HydrophobicContact CD1-CB 4.29Å; Y340-P527 HydrophobicContact CE1-CB 3.93Å; P527-M529 VanDerWaalsContact C-N 3.33Å; P527-M529 HydrophobicContact CB-CG 4.01Å; P527-M529 HydrophobicContact CG-CE 4.17Å; P527-M529 HydrophobicContact CG-CG 3.95Å; P527-M529 HydrophobicContact CG-SD 4.02Å; P527-M529 PolarHBondContact O-N 2.68Å
528	R	73.6	Confident	72.2	Confident	197 Å²	197	115.3 Å²	115.3	74%	0.743	52%	0.518	S	S	*	.			trans	-75.2	85.4	170.6	-71.9	-174.2	176.5	-177.3	-2.5	109.1
529	M	70.1	Confident	69.7	Low	72 Å²	72	120.3 Å²	120.3	36%	0.355	55%	0.55	S	S	.	.	P	Polyproline II helix	trans	-92.4	133.8	178.2	-60.2	-171.8	-68.2	0	0	110.3	R341 P527	R341-M529 PolarHBondContact NH2-SD 2.92Å; R341-M529 VanDerWaalsContact NH2-SD 3.44Å; P527-M529 VanDerWaalsContact C-N 3.33Å; P527-M529 HydrophobicContact CB-CG 4.01Å; P527-M529 HydrophobicContact CG-CE 4.17Å; P527-M529 HydrophobicContact CG-CG 3.95Å; P527-M529 HydrophobicContact CG-SD 4.02Å; P527-M529 PolarHBondContact O-N 2.68Å
530	P	68.3	Low	67.4	Low	22 Å²	22	122.1 Å²	122.1	14%	0.143	56%	0.562	C	S	.	*	P	Polyproline II helix	trans	-66.4	139.3	174.6	27	-32.9	0	0	0	110.3	K335 R469 I532	K335-P530 HydrophobicContact CB-CB 3.96Å; K335-P530 HydrophobicContact CB-CG 4.06Å; R469-P530 VanDerWaalsContact CZ-O 3.29Å; R469-P530 PolarHBondContact NH1-O 3.14Å; R469-P530 PolarHBondContact NH2-O 3.3Å; P530-I532 PolarHBondContact O-N 3.15Å
531	R	62.2	Low	64.7	Low	235 Å²	235	119.5 Å²	119.5	89%	0.887	57%	0.568	S	S	*	*	P	Polyproline II helix	trans	-61.3	128.9	164.9	-70	-178.1	177.9	178.3	-1.4	107.5
532	I	64.3	Low	62.3	Low	26 Å²	26	126.2 Å²	126.2	13%	0.133	59%	0.59	C	S	.	*	P	Polyproline II helix	trans	-84	127.7	166.1	-65.4	172.9	0	0	0	104.4	I324 L332 E468 R469 P530 R534	I324-I532 HydrophobicContact CD1-CG2 3.99Å; L332-I532 HydrophobicContact CD2-CG1 4.26Å; E468-I532 HydrophobicContact CB-CD1 4.31Å; R469-I532 HydrophobicContact CG-CD1 3.77Å; P530-I532 PolarHBondContact O-N 3.15Å; I532-R534 PolarHBondContact O-N 3.38Å
533	P	60.8	Low	59.7	Low	60 Å²	60	131.7 Å²	131.7	39%	0.39	59%	0.593	S	S	.	*	P	Polyproline II helix	trans	-55.5	131.3	172.3	-21.5	32.4	0	0	0	108.4
534	R	58.5	Low	57.3	Low	231 Å²	231	132.9 Å²	132.9	87%	0.872	59%	0.593	S	S	*	*	P	Polyproline II helix	trans	-54.8	145	175.8	-69.9	-171.3	-175.1	-172.6	6	108.9	I532 R536	I532-R534 PolarHBondContact O-N 3.38Å; R534-R536 PolarHBondContact O-N 2.9Å; R534-R536 VanDerWaalsContact O-N 3.08Å
535	P	58.1	Low	55.1	Low	37 Å²	37	131.7 Å²	131.7	24%	0.24	59%	0.594	C	S	.	*	P	Polyproline II helix	trans	-51.8	122.6	172.6	23.5	-34	0	0	0	108.3	D320 S323 H537	D320-P535 HydrophobicContact CB-CB 4Å; D320-P535 HydrophobicContact CB-CG 4.17Å; S323-P535 WeakPolarHBondContact OG-CA 3.34Å; S323-P535 WeakPolarHBondContact OG-CB 3.41Å; P535-H537 VanDerWaalsContact C-N 3.26Å; P535-H537 PolarHBondContact O-N 3.35Å
536	R	53.2	Low	52.9	Low	198 Å²	198	137.3 Å²	137.3	75%	0.747	62%	0.616	S	S	*	*			trans	-70.7	93.7	171.7	-87.6	-172	168	-174.4	-6.4	105.9	R534 K538	R534-R536 PolarHBondContact O-N 2.9Å; R534-R536 VanDerWaalsContact O-N 3.08Å; R536-K538 PolarHBondContact O-N 3.25Å
537	H	47.9	Very low	50.8	Low	133 Å²	133	134.8 Å²	134.8	62%	0.616	61%	0.608	S	S	*	*			trans	-58.7	92	165.1	-71.3	-67.4	0	0	0	107.3	D320 P535 V539	D320-H537 IonicContact OD1-CE1 3.57Å; D320-H537 PolarHBondContact OD1-CE1 2.88Å; D320-H537 IonicContact OD1-ND1 3.57Å; P535-H537 VanDerWaalsContact C-N 3.26Å; P535-H537 PolarHBondContact O-N 3.35Å; H537-V539 HydrophobicContact CB-CG2 4.29Å; H537-V539 PolarHBondContact O-N 3.45Å
538	K	41.9	Very low	48.8	Very low	190 Å²	190	141 Å²	141	83%	0.826	64%	0.639	S	S	*	*			trans	-68.3	94	161	-75.1	-165.3	173.9	-167.7	0	105.7	R536 K540	R536-K538 PolarHBondContact O-N 3.25Å; K538-K540 PolarHBondContact O-N 3.38Å
539	V	38.9	Very low	46.9	Very low	130 Å²	130	139.2 Å²	139.2	79%	0.788	64%	0.644	S	S	*	*			trans	-69.4	65	172.4	-165.9	0	0	0	0	108.9	H537 G541	H537-V539 HydrophobicContact CB-CG2 4.29Å; H537-V539 PolarHBondContact O-N 3.45Å; V539-G541 PolarHBondContact O-N 3.48Å
540	K	41.1	Very low	45.4	Very low	186 Å²	186	140.6 Å²	140.6	81%	0.809	66%	0.661	S	S	*	*			trans	-79	88.8	151.2	-97.7	-166.8	168.4	-170.8	0	105.1	K538 Y542	K538-K540 PolarHBondContact O-N 3.38Å; K540-Y542 PolarHBondContact O-N 2.96Å
541	G	34.6	Very low	43.9	Very low	52 Å²	52	146.7 Å²	146.7	54%	0.536	69%	0.692	S	S	.	*			trans	-51.4	126.1	-168.3	0	0	0	0	0	112.5	V539 R543	V539-G541 PolarHBondContact O-N 3.48Å; G541-R543 PolarHBondContact O-N 3.08Å
542	Y	35.6	Very low	42.5	Very low	181 Å²	181	145.2 Å²	145.2	71%	0.71	70%	0.695	S	S	*	*			trans	-78.4	69.4	156.9	-78	-98.1	0	0	0	107.2	K540 Y544	K540-Y542 PolarHBondContact O-N 2.96Å; Y542-Y544 AromaticContact CD1-CE2 3.68Å; Y542-Y544 HydrophobicContact CD1-CE2 3.68Å; Y542-Y544 AromaticContact CD1-CZ 3.55Å; Y542-Y544 WeakPolarHBondContact CD1-OH 3.39Å; Y542-Y544 WeakPolarHBondContact CE1-OH 3.44Å; Y542-Y544 HydrophobicContact CG-CE2 4.48Å; Y542-Y544 PolarHBondContact O-N 2.89Å
543	R	33.4	Very low	41	Very low	198 Å²	198	149.2 Å²	149.2	75%	0.747	73%	0.726	S	S	*	*			trans	-71.5	66.5	-177.4	-173.6	-169	178.1	147.5	6.8	110.6	G541 E547	G541-R543 PolarHBondContact O-N 3.08Å; R543-E547 IonicContact NE-OE1 3.36Å
544	Y	37.3	Very low	39.7	Very low	166 Å²	166	154.3 Å²	154.3	65%	0.651	75%	0.75	S	S	*	*	S	Bend	trans	-159	25	175.2	31.2	-96.5	0	0	0	112.8	Y542	Y542-Y544 AromaticContact CD1-CE2 3.68Å; Y542-Y544 HydrophobicContact CD1-CE2 3.68Å; Y542-Y544 AromaticContact CD1-CZ 3.55Å; Y542-Y544 WeakPolarHBondContact CD1-OH 3.39Å; Y542-Y544 WeakPolarHBondContact CE1-OH 3.44Å; Y542-Y544 HydrophobicContact CG-CE2 4.48Å; Y542-Y544 PolarHBondContact O-N 2.89Å
545	L	39.7	Very low	38.3	Very low	160 Å²	160	149 Å²	149	84%	0.838	75%	0.748	S	S	*	*	S	Bend	trans	-135.1	6.5	171.5	-76.5	175.1	0	0	0	113.8
546	E	36.4	Very low	37.2	Very low	180 Å²	180	157 Å²	157	84%	0.841	78%	0.782	S	S	*	*	S	Bend	trans	-123.6	10.1	-179.2	-69.6	175.4	166	0	0	112.5	D548	E546-D548 PolarHBondContact O-N 3.2Å
547	E	33	Very low	36.1	Very low	140 Å²	140	151.2 Å²	151.2	65%	0.654	78%	0.784	S	S	*	*	T	Hydrogen-bonded Turn	trans	-93.9	69.3	170.2	-70.5	179.8	-175.2	0	0	109.4	R543	R543-E547 IonicContact NE-OE1 3.36Å
548	D	36.2	Very low	35.5	Very low	167 Å²	167	150.4 Å²	150.4	89%	0.893	79%	0.794	S	S	*	*	T	Hydrogen-bonded Turn	trans	-167.5	34.6	160.7	-107.7	-12.4	0	0	0	112.8	E546	E546-D548 PolarHBondContact O-N 3.2Å
549	N	34.4	Very low	35.1	Very low	160 Å²	160	150.2 Å²	150.2	86%	0.856	80%	0.796	S	S	*	*			trans	-142.5	92.8	164	-137.2	16.7	0	0	0	109
550	S	37.2	Very low	34.8	Very low	100 Å²	100	152.1 Å²	152.1	70%	0.699	80%	0.796	S	S	*	*			trans	-73.4	158.6	177.9	50.6	0	0	0	0	112.1
551	D	36.6	Very low	34.7	Very low	151 Å²	151	150.2 Å²	150.2	81%	0.807	80%	0.795	S	S	*	*			trans	80.1	75.1	168.4	-52.9	-16.8	0	0	0	117.3
552	E	33.4	Very low	35	Very low	203 Å²	203	154.5 Å²	154.5	95%	0.949	81%	0.806	S	S	*	*			trans	-145.1	144.5	132.8	-124.1	169.4	-160.2	0	0	111
553	S	32.5	Very low	35	Very low	111 Å²	111	151.8 Å²	151.8	78%	0.776	80%	0.803	S	S	*	*			trans	-95.9	147.5	-163	53.1	0	0	0	0	114.2
554	D	33.1	Very low	35.3	Very low	166 Å²	166	149.3 Å²	149.3	89%	0.888	80%	0.8	S	S	*	*			trans	-48.4	138.6	-179.8	-63.1	-56.1	0	0	0	115.2
555	S	30.5	Very low	35.6	Very low	121 Å²	121	145 Å²	145	85%	0.846	79%	0.788	S	S	*	*			trans	-146.8	132.9	144	49	0	0	0	0	110.1
556	E	34.8	Very low	35.6	Very low	203 Å²	203	143.6 Å²	143.6	95%	0.949	78%	0.778	S	S	*	*			trans	-79.3	146	-176.4	-60.9	178.9	136.5	0	0	111.6
557	G	29.5	Very low	35.7	Very low	77 Å²	77	142.1 Å²	142.1	79%	0.794	77%	0.771	S	S	*	*			trans	168.1	87	173.9	0	0	0	0	0	112.3
558	S	35.6	Very low	36.2	Very low	117 Å²	117	142.1 Å²	142.1	82%	0.818	77%	0.771	S	S	*	*			trans	-147.9	63.5	179.3	69	0	0	0	0	112.7
559	E	33.7	Very low	36.4	Very low	186 Å²	186	141 Å²	141	87%	0.869	75%	0.754	S	S	*	*	S	Bend	trans	-136.7	17.5	169	-68.4	-165.3	154.4	0	0	113
560	E	33	Very low	36.7	Very low	170 Å²	170	137.8 Å²	137.8	79%	0.794	74%	0.74	S	S	*	*	S	Bend	trans	-104	-15	-178.4	-65.9	-174.6	158.5	0	0	114.8	D562	E560-D562 PolarHBondContact O-N 3.17Å
561	D	38.9	Very low	37	Very low	146 Å²	146	138 Å²	138	78%	0.781	73%	0.73	S	S	*	*	T	Hydrogen-bonded Turn	trans	-75.5	-17.9	-173.8	-86.3	-6.7	0	0	0	115.3
562	D	41.2	Very low	37.1	Very low	142 Å²	142	137.1 Å²	137.1	76%	0.759	72%	0.721	S	S	*	*	T	Hydrogen-bonded Turn	trans	-86.3	-21.6	-176.4	-88.7	-26.9	0	0	0	113.2	E560	E560-D562 PolarHBondContact O-N 3.17Å
563	D	35	Very low	37.7	Very low	123 Å²	123	133.3 Å²	133.3	66%	0.658	71%	0.707	S	S	*	*	T	Hydrogen-bonded Turn	trans	-83.8	-33.9	-178.6	-77.9	-29.3	0	0	0	112.7	D565 E566 E567	D563-D565 PolarHBondContact O-N 3.13Å; D563-E566 PolarHBondContact O-N 2.81Å; D563-E567 PolarHBondContact O-N 2.94Å
564	E	40.1	Very low	38.1	Very low	146 Å²	146	135.1 Å²	135.1	68%	0.682	70%	0.704	S	S	*	*	H	α-helix	trans	-61.8	-30.9	174.5	-67.5	-163	159.6	0	0	112.2	E566 E567 E568	E564-E566 VanDerWaalsContact C-N 3.33Å; E564-E566 PolarHBondContact O-N 2.61Å; E564-E567 PolarHBondContact O-N 3.17Å; E564-E568 PolarHBondContact O-N 2.54Å
565	D	42	Very low	38.6	Very low	75 Å²	75	134.6 Å²	134.6	40%	0.401	69%	0.689	S	S	.	*	H	α-helix	trans	-78	-13.4	-176.6	-138.6	46.6	0	0	0	112.9	D563 R569	D563-D565 PolarHBondContact O-N 3.13Å; D565-R569 WeakPolarHBondContact O-CG 3.4Å; D565-R569 PolarHBondContact O-NE 3.2Å; D565-R569 IonicContact OD2-NH2 3.3Å
566	E	41.1	Very low	39.4	Very low	132 Å²	132	132.6 Å²	132.6	62%	0.617	67%	0.671	S	S	*	*	H	α-helix	trans	-93.1	-39.2	168.2	-70.5	-114.7	133	0	0	111.7	D563 E564 R569 T570	D563-E566 PolarHBondContact O-N 2.81Å; E564-E566 VanDerWaalsContact C-N 3.33Å; E564-E566 PolarHBondContact O-N 2.61Å; E566-R569 PolarHBondContact O-N 2.76Å; E566-R569 VanDerWaalsContact O-N 3.15Å; E566-T570 PolarHBondContact O-N 3.08Å; E566-T570 PolarHBondContact O-OG1 2.84Å
567	E	37.3	Very low	40	Very low	148 Å²	148	127.2 Å²	127.2	69%	0.692	65%	0.652	S	S	*	*	H	α-helix	trans	-65.9	-38.8	176	-69.1	-160.4	156.3	0	0	112.8	D563 E564 R569 T570 E571	D563-E567 PolarHBondContact O-N 2.94Å; E564-E567 PolarHBondContact O-N 3.17Å; E567-R569 PolarHBondContact O-N 3.49Å; E567-T570 PolarHBondContact O-N 3.42Å; E567-T570 PolarHBondContact O-OG1 3.26Å; E567-T570 VanDerWaalsContact O-OG1 3.13Å; E567-E571 PolarHBondContact O-N 2.82Å; E567-E571 VanDerWaalsContact O-N 3.12Å
568	E	43.5	Very low	40.6	Very low	140 Å²	140	130.7 Å²	130.7	65%	0.654	65%	0.648	S	S	*	*	H	α-helix	trans	-61.6	-27.9	172.7	-83.5	-148.6	148.5	0	0	112.4	E564 E572	E564-E568 PolarHBondContact O-N 2.54Å; E568-E572 PolarHBondContact O-N 3.46Å
569	R	41.6	Very low	41.1	Very low	144 Å²	144	132.8 Å²	132.8	54%	0.543	65%	0.645	S	S	.	*	H	α-helix	trans	-77.5	-39	179.3	-71.1	-176.6	-163.9	162.8	16.7	113.1	D565 E566 E567 E571 E572 D573	D565-R569 WeakPolarHBondContact O-CG 3.4Å; D565-R569 PolarHBondContact O-NE 3.2Å; D565-R569 IonicContact OD2-NH2 3.3Å; E566-R569 PolarHBondContact O-N 2.76Å; E566-R569 VanDerWaalsContact O-N 3.15Å; E567-R569 PolarHBondContact O-N 3.49Å; R569-E571 VanDerWaalsContact C-N 3.31Å; R569-E572 PolarHBondContact O-N 2.77Å; R569-D573 PolarHBondContact O-N 2.89Å; R569-D573 VanDerWaalsContact O-N 3.09Å
570	T	41.1	Very low	41.5	Very low	92 Å²	92	130.4 Å²	130.4	56%	0.564	64%	0.635	S	S	*	*	H	α-helix	trans	-65.8	-37.2	173.3	27	0	0	0	0	110.9	E566 E567 E574	E566-T570 PolarHBondContact O-N 3.08Å; E566-T570 PolarHBondContact O-OG1 2.84Å; E567-T570 PolarHBondContact O-N 3.42Å; E567-T570 PolarHBondContact O-OG1 3.26Å; E567-T570 VanDerWaalsContact O-OG1 3.13Å; T570-E574 PolarHBondContact O-N 3.31Å; T570-E574 VanDerWaalsContact O-N 3.14Å
571	E	41.7	Very low	42	Very low	104 Å²	104	125.9 Å²	125.9	49%	0.486	62%	0.619	S	S	.	*	H	α-helix	trans	-66.8	-35.1	171.3	-73	-152.5	166.4	0	0	113.8	E567 R569 R575	E567-E571 PolarHBondContact O-N 2.82Å; E567-E571 VanDerWaalsContact O-N 3.12Å; R569-E571 VanDerWaalsContact C-N 3.31Å; E571-R575 WeakPolarHBondContact O-CB 3.24Å; E571-R575 WeakPolarHBondContact O-CD 3.25Å; E571-R575 WeakPolarHBondContact O-CG 3.24Å; E571-R575 PolarHBondContact O-N 3.14Å; E571-R575 VanDerWaalsContact O-N 3.14Å; E571-R575 IonicContact OE2-CZ 3.53Å; E571-R575 VanDerWaalsContact OE2-CZ 3.29Å; E571-R575 IonicContact OE2-NE 2.58Å; E571-R575 IonicContact OE2-NH2 3.29Å; E571-R575 PolarHBondContact OE2-NH2 3.29Å
572	E	40.2	Very low	42.2	Very low	134 Å²	134	121.7 Å²	121.7	63%	0.626	61%	0.605	S	S	*	*	H	α-helix	trans	-66.3	-42.2	174.8	-80.4	-154.4	146	0	0	112.1	E568 R569 V576	E568-E572 PolarHBondContact O-N 3.46Å; R569-E572 PolarHBondContact O-N 2.77Å; E572-V576 VanDerWaalsContact O-CG2 3.28Å; E572-V576 WeakPolarHBondContact O-CG2 3.43Å; E572-V576 PolarHBondContact O-N 3.03Å; E572-V576 VanDerWaalsContact O-N 3.08Å
573	D	44.8	Very low	42	Very low	122 Å²	122	116.8 Å²	116.8	65%	0.652	59%	0.588	S	S	*	*	H	α-helix	trans	-67.6	-40.6	178.7	-89.9	-15.6	0	0	0	112.3	R569 V576 V577	R569-D573 PolarHBondContact O-N 2.89Å; R569-D573 VanDerWaalsContact O-N 3.09Å; D573-V576 PolarHBondContact O-N 3.22Å; D573-V577 WeakPolarHBondContact O-CG2 3.39Å; D573-V577 PolarHBondContact O-N 3.02Å
574	E	41.6	Very low	42.2	Very low	150 Å²	150	117.7 Å²	117.7	70%	0.701	59%	0.593	S	S	*	*	H	α-helix	trans	-65	-42.4	175.5	-72.3	-160.7	153	0	0	112.4	T570 V576 V577 E578	T570-E574 PolarHBondContact O-N 3.31Å; T570-E574 VanDerWaalsContact O-N 3.14Å; E574-V576 VanDerWaalsContact C-N 3.33Å; E574-V576 PolarHBondContact O-N 3.29Å; E574-V577 PolarHBondContact O-N 3.49Å; E574-E578 PolarHBondContact O-N 3.4Å
575	R	42.8	Very low	42	Very low	155 Å²	155	120.2 Å²	120.2	59%	0.585	60%	0.596	S	S	*	*	H	α-helix	trans	-66.2	-32.7	178.3	-70.4	170.1	-173	-172.9	3.2	112.8	E571 E579	E571-R575 WeakPolarHBondContact O-CB 3.24Å; E571-R575 WeakPolarHBondContact O-CD 3.25Å; E571-R575 WeakPolarHBondContact O-CG 3.24Å; E571-R575 PolarHBondContact O-N 3.14Å; E571-R575 VanDerWaalsContact O-N 3.14Å; E571-R575 IonicContact OE2-CZ 3.53Å; E571-R575 VanDerWaalsContact OE2-CZ 3.29Å; E571-R575 IonicContact OE2-NE 2.58Å; E571-R575 IonicContact OE2-NH2 3.29Å; E571-R575 PolarHBondContact OE2-NH2 3.29Å; R575-E579 PolarHBondContact O-N 2.69Å
576	V	47.9	Very low	41.9	Very low	78 Å²	78	125 Å²	125	47%	0.473	62%	0.616	S	S	.	*	H	α-helix	trans	-68.6	-37	174.2	168.3	0	0	0	0	111.3	E572 D573 E574 M580	E572-V576 VanDerWaalsContact O-CG2 3.28Å; E572-V576 WeakPolarHBondContact O-CG2 3.43Å; E572-V576 PolarHBondContact O-N 3.03Å; E572-V576 VanDerWaalsContact O-N 3.08Å; D573-V576 PolarHBondContact O-N 3.22Å; E574-V576 VanDerWaalsContact C-N 3.33Å; E574-V576 PolarHBondContact O-N 3.29Å; V576-M580 WeakPolarHBondContact O-CG 3.35Å; V576-M580 PolarHBondContact O-N 3.15Å; V576-M580 VanDerWaalsContact O-N 3.15Å
577	V	47.5	Very low	41.6	Very low	91 Å²	91	127.5 Å²	127.5	55%	0.552	63%	0.627	S	S	*	*	H	α-helix	trans	-68	-41.4	174.3	174.5	0	0	0	0	111.2	D573 E574 M580 V581	D573-V577 WeakPolarHBondContact O-CG2 3.39Å; D573-V577 PolarHBondContact O-N 3.02Å; E574-V577 PolarHBondContact O-N 3.49Å; V577-M580 PolarHBondContact O-N 3.23Å; V577-V581 WeakPolarHBondContact O-CG2 3.17Å; V577-V581 PolarHBondContact O-N 2.91Å; V577-V581 VanDerWaalsContact O-N 3.07Å
578	E	41.6	Very low	41.5	Very low	149 Å²	149	124 Å²	124	70%	0.696	63%	0.631	S	S	*	*	H	α-helix	trans	-64	-43.1	175	-73.8	-155.3	131.4	0	0	113.3	E574 M580 V581 A582	E574-E578 PolarHBondContact O-N 3.4Å; E578-M580 VanDerWaalsContact C-N 3.31Å; E578-M580 PolarHBondContact O-N 2.96Å; E578-V581 PolarHBondContact O-N 3.37Å; E578-A582 WeakPolarHBondContact O-CB 3.49Å; E578-A582 PolarHBondContact O-N 2.99Å
579	E	47	Very low	40.9	Very low	162 Å²	162	120.2 Å²	120.2	76%	0.757	63%	0.63	S	S	*	*	H	α-helix	trans	-64.2	-32.9	175.7	-83.5	-156.7	149.5	0	0	112.4	R575 G583	R575-E579 PolarHBondContact O-N 2.69Å; E579-G583 PolarHBondContact O-N 3.06Å; E579-G583 VanDerWaalsContact O-N 3.12Å
580	M	42.3	Very low	40.4	Very low	136 Å²	136	124.8 Å²	124.8	67%	0.67	65%	0.647	S	S	*	*	H	α-helix	trans	-66.1	-45.1	173	-76.7	-170.1	174	0	0	112.1	V576 V577 E578 A582 G583 D584	V576-M580 WeakPolarHBondContact O-CG 3.35Å; V576-M580 PolarHBondContact O-N 3.15Å; V576-M580 VanDerWaalsContact O-N 3.15Å; V577-M580 PolarHBondContact O-N 3.23Å; E578-M580 VanDerWaalsContact C-N 3.31Å; E578-M580 PolarHBondContact O-N 2.96Å; M580-A582 VanDerWaalsContact C-N 3.3Å; M580-A582 PolarHBondContact O-N 3.03Å; M580-G583 PolarHBondContact O-N 3.03Å; M580-D584 PolarHBondContact O-N 3.48Å
581	V	42.1	Very low	39.9	Very low	75 Å²	75	128.5 Å²	128.5	46%	0.455	66%	0.663	S	S	.	*	H	α-helix	trans	-69	-27.9	178.8	174.2	0	0	0	0	112.3	V577 E578	V577-V581 WeakPolarHBondContact O-CG2 3.17Å; V577-V581 PolarHBondContact O-N 2.91Å; V577-V581 VanDerWaalsContact O-N 3.07Å; E578-V581 PolarHBondContact O-N 3.37Å
582	A	43.6	Very low	39.3	Very low	58 Å²	58	128.5 Å²	128.5	48%	0.479	68%	0.681	S	S	.	*	H	α-helix	trans	-70.5	-39.7	172	0	0	0	0	0	112.4	E578 M580 R585	E578-A582 WeakPolarHBondContact O-CB 3.49Å; E578-A582 PolarHBondContact O-N 2.99Å; M580-A582 VanDerWaalsContact C-N 3.3Å; M580-A582 PolarHBondContact O-N 3.03Å; A582-R585 PolarHBondContact O-N 3.36Å
583	G	37.9	Very low	38.6	Very low	39 Å²	39	134.1 Å²	134.1	40%	0.402	70%	0.697	S	S	.	*	H	α-helix	trans	-60.6	-48.1	178.4	0	0	0	0	0	113.5	E579 M580 R585 E586	E579-G583 PolarHBondContact O-N 3.06Å; E579-G583 VanDerWaalsContact O-N 3.12Å; M580-G583 PolarHBondContact O-N 3.03Å; G583-R585 PolarHBondContact O-N 3.12Å; G583-E586 PolarHBondContact O-N 3.05Å
584	D	38.9	Very low	37.7	Very low	142 Å²	142	132.6 Å²	132.6	76%	0.759	70%	0.701	S	S	*	*	H	α-helix	trans	-66.6	-18.3	-178.6	-80.4	-5.7	0	0	0	113.5	M580	M580-D584 PolarHBondContact O-N 3.48Å
585	R	36.1	Very low	37	Very low	198 Å²	198	135.1 Å²	135.1	75%	0.747	71%	0.713	S	S	*	*	H	α-helix	trans	-82.1	-23.9	175.2	-83	-174.8	171.5	130.4	-1.5	114.2	A582 G583	A582-R585 PolarHBondContact O-N 3.36Å; G583-R585 PolarHBondContact O-N 3.12Å
586	E	39.3	Very low	36.2	Very low	176 Å²	176	131.3 Å²	131.3	82%	0.822	72%	0.722	S	S	*	*	H	α-helix	trans	-86.1	-23	-178.9	-68.9	-157.8	142.5	0	0	113.7	G583	G583-E586 PolarHBondContact O-N 3.05Å
587	E	35.8	Very low	35.2	Very low	184 Å²	184	132.1 Å²	132.1	86%	0.86	74%	0.737	S	S	*	*	T	Hydrogen-bonded Turn	trans	-87.2	-14	178.6	-66.8	-158.5	147.4	0	0	114.7	G589	E587-G589 PolarHBondContact O-N 3.06Å
588	G	33.7	Very low	34.2	Very low	75 Å²	75	135.6 Å²	135.6	77%	0.773	75%	0.753	S	S	*	*	T	Hydrogen-bonded Turn	trans	-85.4	3.5	-179.1	0	0	0	0	0	116.7
589	G	31.5	Very low	33.3	Very low	60 Å²	60	133.9 Å²	133.9	62%	0.619	76%	0.757	S	S	*	*			trans	-115.8	20.1	-153	0	0	0	0	0	119	E587	E587-G589 PolarHBondContact O-N 3.06Å
590	R	30.7	Very low	33.4	Very low	240 Å²	240	132.3 Å²	132.3	91%	0.906	76%	0.761	S	S	*	*			trans	-145.5	80.4	176.2	-72.2	-168.1	-179	159	5.6	114.7
591	D	30.1	Very low	32.7	Very low	170 Å²	170	129.3 Å²	129.3	91%	0.909	77%	0.765	S	S	*	*			trans	-154.4	155.8	148.8	-106.5	-35.1	0	0	0	111.6
592	A	29.4	Very low	32	Very low	104 Å²	104	130.7 Å²	130.7	86%	0.86	78%	0.784	S	S	*	*			trans	94	105.6	179.9	0	0	0	0	0	118
593	R	25.3	Very low	31.2	Very low	252 Å²	252	139.4 Å²	139.4	95%	0.951	81%	0.805	S	S	*	*			trans	-137.6	96.3	156	-173.6	-173.3	-170.7	-172.1	4.2	109.7
594	A	26.6	Very low	30.7	Very low	91 Å²	91	149 Å²	149	75%	0.752	83%	0.828	S	S	*	*			trans	-153.6	126.3	164.8	0	0	0	0	0	110.7
595	E	26.9	Very low	30.2	Very low	202 Å²	202	154 Å²	154	94%	0.944	84%	0.837	S	S	*	*			trans	44.9	137.2	146.2	-54.3	-174.3	144.8	0	0	122.5
596	G	25.7	Very low	29.8	Very low	75 Å²	75	148.4 Å²	148.4	77%	0.773	84%	0.841	S	S	*	*			trans	131.1	87.4	141.8	0	0	0	0	0	119.3
597	A	26.2	Very low	29.3	Very low	96 Å²	96	144.5 Å²	144.5	79%	0.793	84%	0.839	S	S	*	*			trans	60	139.1	138.7	0	0	0	0	0	124.2
598	D	26.5	Very low	28.9	Very low	164 Å²	164	145 Å²	145	88%	0.877	84%	0.841	S	S	*	*			trans	73.5	151.8	147.1	-70.6	-21.5	0	0	0	124.3
599	S	24.4	Very low	28.8	Very low	112 Å²	112	144.9 Å²	144.9	78%	0.783	84%	0.839	S	S	*	*			trans	-111.4	-163.2	-165.1	-64.5	0	0	0	0	111.1
600	P	48.7	Very low	28.6	Very low	130 Å²	130	154 Å²	154	84%	0.844	86%	0.855	S	S	*	*				-128.5	177.8	-67.2	36.9	-22.5	0	0	0	112.6
601	G	26.3	Very low	28.5	Very low	73 Å²	73	145.9 Å²	145.9	75%	0.753	85%	0.846	S	S	*	*			trans	159	154.6	150.5	0	0	0	0	0	119.8
602	A	28.2	Very low	28.5	Very low	104 Å²	104	142.5 Å²	142.5	86%	0.86	84%	0.842	S	S	*	*			trans	61.2	112.3	170.5	0	0	0	0	0	117.1
603	R	27.2	Very low	28.6	Very low	241 Å²	241	147.2 Å²	147.2	91%	0.909	85%	0.846	S	S	*	*			cis	80	90.1	20.5	-153.5	-168.7	-159.5	-168.3	9.1	117
604	R	28.1	Very low	28.9	Very low	239 Å²	239	139 Å²	139	90%	0.902	83%	0.832	S	S	*	*			trans	-164.3	119.3	145.2	-102.5	170.8	-177.8	-167	-1	106.9
605	R	27.9	Very low	29.2	Very low	247 Å²	247	144 Å²	144	93%	0.932	84%	0.84	S	S	*	*				46.3	124.8	79.8	-77.8	-171.7	171.7	-176.5	-2.8	111.6
606	G	26.6	Very low	29.4	Very low	82 Å²	82	142.1 Å²	142.1	85%	0.845	84%	0.836	S	S	*	*			cis	-177.4	-174.1	8.6	0	0	0	0	0	105.5
607	A	29	Very low	29.8	Very low	93 Å²	93	146 Å²	146	77%	0.769	84%	0.839	S	S	*	*			cis	-147.2	143.4	10.3	0	0	0	0	0	107.3
608	E	28.9	Very low	29.9	Very low	196 Å²	196	144.6 Å²	144.6	92%	0.916	83%	0.834	S	S	*	*				52.5	126	92.6	-78.9	-165	135	0	0	118.5
609	G	30.4	Very low	30.2	Very low	71 Å²	71	146.9 Å²	146.9	73%	0.732	83%	0.83	S	S	*	*			trans	139.5	84.4	176.7	0	0	0	0	0	110.6
610	R	27.7	Very low	30.7	Very low	252 Å²	252	148.7 Å²	148.7	95%	0.951	83%	0.826	S	S	*	*				45.9	127.5	76.1	-70.3	-170.8	176.7	-164.5	0	113.1
611	G	29.1	Very low	30	Very low	69 Å²	69	154 Å²	154	71%	0.711	85%	0.845	S	S	*	*			cis	-149.5	157.9	-2.1	0	0	0	0	0	109.6
612	A	30	Very low	30.2	Very low	100 Å²	100	158.1 Å²	158.1	83%	0.826	85%	0.85	S	S	*	*				67.3	98.5	67.6	0	0	0	0	0	113.9
613	H	30.1	Very low	30.3	Very low	203 Å²	203	160.9 Å²	160.9	94%	0.94	85%	0.849	S	S	*	*			trans	-143.1	137.5	138.8	-119	-71.8	0	0	0	108.6
614	A	32.4	Very low	30.5	Very low	79 Å²	79	156.5 Å²	156.5	65%	0.653	85%	0.846	S	S	*	*			trans	-125	155.2	-174	0	0	0	0	0	110.8
615	E	32.3	Very low	30.6	Very low	197 Å²	197	151.6 Å²	151.6	92%	0.921	84%	0.843	S	S	*	*			trans	41	140.8	145.3	-68.2	176.8	140.7	0	0	122.3
616	D	32	Very low	30.8	Very low	161 Å²	161	145.7 Å²	145.7	86%	0.861	84%	0.837	S	S	*	*			trans	-88.3	168.6	177.3	-174.3	23	0	0	0	111.9
617	D	34.7	Very low	31.1	Very low	157 Å²	157	149.9 Å²	149.9	84%	0.84	84%	0.837	S	S	*	*			trans	118	122.7	162.4	-156.3	8.2	0	0	0	115.8
618	G	28.3	Very low	31.2	Very low	67 Å²	67	154 Å²	154	69%	0.691	84%	0.842	S	S	*	*			trans	176.8	34.6	-163.4	0	0	0	0	0	120.7
619	R	32.7	Very low	31.4	Very low	212 Å²	212	150.8 Å²	150.8	80%	0.8	84%	0.836	S	S	*	*			trans	69.3	147.6	154.8	-84.8	177.1	174.4	-146.6	10.5	123
620	E	33.8	Very low	31.5	Very low	150 Å²	150	157.4 Å²	157.4	70%	0.701	85%	0.845	S	S	*	*			trans	60.2	114.4	148.8	-65.4	165.8	-146.2	0	0	115.3
621	I	34.5	Very low	31.8	Very low	242 Å²	242	148.8 Å²	148.8	100%	1.241	84%	0.835	S	S	*	*			cis	-147.4	0	42.8	-76.6	171.7	0	0	0	110.9

Retrieved 621 of 621 residues in 492.3 ms (Link to these results)

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