A0A096MHP5_POEFO Loading...

Sodium-coupled neutral amino acid symporter 2

AlphaFold DB , UniProt , Accession A0A096MHP5, Species POEFO (Poecilia formosa, Amazon molly), Gene n/a, Length 492 aa.

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(Predicted Aligned Error values between residue pairs)

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Site	Residue	pLDDT	pLDDT confidence	pLDDT₁₀	pLDDT10 confidence	SASA	SASA [Å²]	SASA₁₀	SASA10 [Å²]	RSA	RSA unformatted	RSA₁₀	RSA10 unformatted	Surface	Surface10 (not used)	Disorder (not used)	Disorder	Sec. str.	Secondary structure	Isomer	Phi (φ)	Psi (ψ)	Omega (ω)	Chi 1 (χ₁)	Chi 2 (χ₂)	Chi 3 (χ₃)	Chi 4 (χ₄)	Chi 5 (χ₅)	Tau (τ)	Contacts (colored by PAE)	Contact details
1	S	30.6	Very low	29.3	Very low	175 Å²	175	150.9 Å²	150.9	100%	1.224	85%	0.847	S	S	*	*				0	146	0	-50.9	0	0	0	0	109.8
2	C	29.2	Very low	29.1	Very low	135 Å²	135	151.8 Å²	151.8	91%	0.912	85%	0.848	S	S	*	*			trans	-70.9	155.8	179.9	-52.5	0	0	0	0	111.9
3	K	25.1	Very low	28.9	Very low	212 Å²	212	148.1 Å²	148.1	92%	0.922	84%	0.839	S	S	*	*			trans	-140.2	139	161.6	-139.4	179.3	-176.8	-172.7	0	108.4
4	M	29	Very low	28.6	Very low	176 Å²	176	147.1 Å²	147.1	87%	0.867	84%	0.844	S	S	*	*			trans	-94.7	-159.5	174.9	-64.2	179.3	165.2	0	0	109.4
5	P	49	Very low	28.2	Very low	95 Å²	95	144.5 Å²	144.5	62%	0.617	84%	0.838	S	S	*	*				-134.1	-178.7	-81.8	41.4	-25.8	0	0	0	113.9
6	Y	28.4	Very low	28	Very low	230 Å²	230	142.4 Å²	142.4	90%	0.902	83%	0.834	S	S	*	*			trans	61.8	164.3	159.6	-70.8	-56.3	0	0	0	116.7
7	A	26.9	Very low	27.9	Very low	99 Å²	99	144.3 Å²	144.3	82%	0.818	84%	0.837	S	S	*	*			cis	-157.8	-180	-18.4	0	0	0	0	0	108.9
8	G	24.9	Very low	27.7	Very low	60 Å²	60	141.6 Å²	141.6	62%	0.619	83%	0.828	S	S	*	*			trans	127.2	129	-179	0	0	0	0	0	110
9	E	25.6	Very low	27.7	Very low	180 Å²	180	141.7 Å²	141.7	84%	0.841	83%	0.825	S	S	*	*			cis	63.1	124.4	42.7	-54.5	175.3	159.1	0	0	111.7
10	D	25.5	Very low	27.5	Very low	141 Å²	141	141 Å²	141	75%	0.754	82%	0.818	S	S	*	*			cis	-154.4	-171	-7.6	-107.2	-22.7	0	0	0	110.2
11	D	28.5	Very low	27.4	Very low	157 Å²	157	143 Å²	143	84%	0.84	82%	0.817	S	S	*	*			trans	-4.4	132	167	-70.8	-32.3	0	0	0	118.8
12	D	27	Very low	27.2	Very low	161 Å²	161	139.1 Å²	139.1	86%	0.861	79%	0.788	S	S	*	*				-150.6	143.4	129	-139.9	-21.9	0	0	0	113.2
13	S	25.6	Very low	26.8	Very low	104 Å²	104	138.8 Å²	138.8	73%	0.727	79%	0.786	S	S	*	*			trans	-103.7	131.9	-179.6	66.1	0	0	0	0	110.7
14	C	25	Very low	26.7	Very low	135 Å²	135	137.7 Å²	137.7	91%	0.912	78%	0.781	S	S	*	*			trans	-137.1	148.5	171.9	-97.7	0	0	0	0	113
15	S	23.5	Very low	26.5	Very low	108 Å²	108	138.3 Å²	138.3	76%	0.755	78%	0.779	S	S	*	*			trans	-96.3	151.2	-158	48	0	0	0	0	115
16	S	24.7	Very low	25.2	Very low	110 Å²	110	137.6 Å²	137.6	77%	0.769	79%	0.789	S	S	*	*			trans	-5.7	132.7	153.9	57	0	0	0	0	119.5
17	I	25.8	Very low	24.9	Very low	175 Å²	175	137.1 Å²	137.1	90%	0.897	79%	0.785	S	S	*	*			trans	-137.8	140.9	134.7	-93.1	164.3	0	0	0	107.3
18	S	25.1	Very low	24.7	Very low	95 Å²	95	140.6 Å²	140.6	66%	0.664	79%	0.789	S	S	*	*			trans	-105.8	179.4	173.5	55.2	0	0	0	0	110
19	D	26.8	Very low	24.6	Very low	144 Å²	144	143.6 Å²	143.6	77%	0.77	79%	0.791	S	S	*	*			cis	-141.9	172.5	6.8	-16.7	-88	0	0	0	108.2
20	D	24.5	Very low	24.5	Very low	128 Å²	128	146.5 Å²	146.5	68%	0.684	80%	0.795	S	S	*	*			cis	-150.7	-144.4	-11.5	-152.7	0.3	0	0	0	106.3
21	F	24.9	Very low	24.4	Very low	184 Å²	184	143.3 Å²	143.3	81%	0.807	80%	0.795	S	S	*	*			cis	-144.4	135.6	-0.3	-161.2	-82.7	0	0	0	109.4
22	P	26.2	Very low	24.2	Very low	93 Å²	93	145.2 Å²	145.2	60%	0.604	80%	0.798	S	S	*	*			trans	-96.3	160.6	-166.4	36.5	-37.4	0	0	0	115.3
23	C	20.6	Very low	24.1	Very low	128 Å²	128	146.6 Å²	146.6	87%	0.865	80%	0.8	S	S	*	*			trans	-153.9	104.1	160.6	-174	0	0	0	0	112.4
24	F	23.4	Very low	24.4	Very low	189 Å²	189	147.6 Å²	147.6	83%	0.829	80%	0.804	S	S	*	*			trans	-162.6	156.8	157.4	-140.3	-93.2	0	0	0	113.4
25	K	24.3	Very low	24.5	Very low	189 Å²	189	149.6 Å²	149.6	82%	0.822	81%	0.805	S	S	*	*			trans	66.4	102.9	161	-110.5	165.1	-174.4	172.6	0	118.8
26	G	22.5	Very low	24.4	Very low	80 Å²	80	152.6 Å²	152.6	83%	0.825	81%	0.812	S	S	*	*			trans	-90.7	147.1	142.1	0	0	0	0	0	110.7
27	R	21.9	Very low	24.5	Very low	219 Å²	219	151 Å²	151	83%	0.826	81%	0.813	S	S	*	*			trans	-119.6	142.6	170.3	168.5	-170	-94	-169	-6.4	107.9
28	L	23.1	Very low	24.3	Very low	173 Å²	173	149.8 Å²	149.8	91%	0.906	80%	0.803	S	S	*	*			trans	-128.9	171.7	153.7	-104.3	103.5	0	0	0	109.6
29	D	22.2	Very low	24.4	Very low	123 Å²	123	154.8 Å²	154.8	66%	0.658	81%	0.809	S	S	*	*			trans	-125.6	-159.8	-139.8	-150.9	-14.8	0	0	0	113.6
30	W	23.8	Very low	25	Very low	241 Å²	241	152.4 Å²	152.4	91%	0.913	80%	0.802	S	S	*	*			trans	81.4	128.9	-176.3	-38.7	110.5	0	0	0	113.8
31	G	23.6	Very low	25.1	Very low	73 Å²	73	152.9 Å²	152.9	75%	0.753	80%	0.804	S	S	*	*			cis	155	108.7	-5.5	0	0	0	0	0	111
32	E	24.6	Very low	25.1	Very low	197 Å²	197	148.5 Å²	148.5	92%	0.921	80%	0.797	S	S	*	*			trans	-91.1	146.3	-173	-66.2	-179.5	114.8	0	0	113.8
33	Q	24.7	Very low	25.2	Very low	191 Å²	191	152 Å²	152	89%	0.893	81%	0.81	S	S	*	*			trans	-138.8	138	158.7	-74.6	-167.7	-36.6	0	0	109.6
34	P	30.4	Very low	25.5	Very low	125 Å²	125	152 Å²	152	81%	0.812	81%	0.806	S	S	*	*			trans	-87.1	157.7	178	35.6	-35	0	0	0	112.3
35	L	27.5	Very low	25.7	Very low	177 Å²	177	151.6 Å²	151.6	93%	0.927	81%	0.807	S	S	*	*			trans	-135.7	127.1	164.6	-85.8	169	0	0	0	109.9
36	D	22.8	Very low	25.9	Very low	170 Å²	170	150.1 Å²	150.1	91%	0.909	81%	0.808	S	S	*	*			trans	-71.7	149.1	172.7	-89.4	-54.5	0	0	0	112.1
37	G	26.7	Very low	26.2	Very low	76 Å²	76	154.9 Å²	154.9	78%	0.784	81%	0.809	S	S	*	*			trans	-165.1	130.9	172.6	0	0	0	0	0	109.8
38	Q	21.8	Very low	26.5	Very low	150 Å²	150	151.9 Å²	151.9	70%	0.701	81%	0.809	S	S	*	*			trans	-135.7	133.5	-150.7	-173.9	174.3	0.7	0	0	114.5
39	Y	26.2	Very low	26.7	Very low	200 Å²	200	153.4 Å²	153.4	78%	0.784	81%	0.809	S	S	*	*			trans	69.3	158.4	167.8	-67.7	-39.3	0	0	0	118.9
40	P	38.8	Very low	27.1	Very low	95 Å²	95	156.1 Å²	156.1	62%	0.617	82%	0.823	S	S	*	*			cis	-140.6	-154.7	-43.9	40.5	-22.2	0	0	0	113.1
41	D	27.1	Very low	27.3	Very low	137 Å²	137	149.6 Å²	149.6	73%	0.733	81%	0.814	S	S	*	*			trans	75.3	98.2	164.2	-57.6	-13.2	0	0	0	116.4
42	S	24.8	Very low	27.4	Very low	93 Å²	93	154 Å²	154	65%	0.65	82%	0.82	S	S	*	*				72.7	127.3	86.6	73.8	0	0	0	0	112.8
43	D	27.7	Very low	27.6	Very low	165 Å²	165	153.4 Å²	153.4	88%	0.882	82%	0.817	S	S	*	*				-117.7	168.2	56.9	-71.4	-49.9	0	0	0	117.6
44	T	28.2	Very low	27.7	Very low	128 Å²	128	154 Å²	154	79%	0.785	82%	0.816	S	S	*	*			trans	-127.5	107.1	-175.1	-55.6	0	0	0	0	111.5
45	E	27.3	Very low	27.7	Very low	181 Å²	181	152.8 Å²	152.8	85%	0.846	82%	0.817	S	S	*	*			trans	-157.1	150.2	157.5	-124.6	172.8	-166.6	0	0	112.1
46	N	28	Very low	27.7	Very low	158 Å²	158	150.2 Å²	150.2	85%	0.845	81%	0.814	S	S	*	*			trans	77.1	33.2	-176.3	-56	-63.5	0	0	0	118.7	N48	N46-N48 PolarHBondContact O-N 3.49Å
47	Q	28.3	Very low	27.9	Very low	181 Å²	181	150.7 Å²	150.7	85%	0.846	81%	0.808	S	S	*	*			trans	-75.8	104	138.7	-78.4	-170	-5	0	0	108.7
48	N	28.4	Very low	27.8	Very low	155 Å²	155	153.3 Å²	153.3	83%	0.829	80%	0.804	S	S	*	*			trans	168	74.4	150.9	-89.8	-31.1	0	0	0	111.8	N46	N46-N48 PolarHBondContact O-N 3.49Å
49	F	26.9	Very low	28	Very low	205 Å²	205	152.6 Å²	152.6	90%	0.899	81%	0.805	S	S	*	*			trans	-167.2	62.7	150.3	-113.2	-67.1	0	0	0	111.7
50	L	30.6	Very low	28.1	Very low	181 Å²	181	154.8 Å²	154.8	95%	0.948	81%	0.814	S	S	*	*			trans	-121	112.5	166.4	-75.9	175.5	0	0	0	109.3
51	S	28.3	Very low	27.6	Very low	104 Å²	104	158.2 Å²	158.2	73%	0.727	82%	0.821	S	S	*	*			trans	-132.4	105.9	171.9	59.6	0	0	0	0	109.6
52	D	27.3	Very low	28	Very low	164 Å²	164	157.8 Å²	157.8	88%	0.877	82%	0.824	S	S	*	*			trans	48	117.8	170	-70.1	-35.4	0	0	0	121	K54	D52-K54 PolarHBondContact O-N 3.31Å
53	H	28.4	Very low	28.5	Very low	186 Å²	186	162.4 Å²	162.4	86%	0.861	84%	0.835	S	S	*	*			trans	-58.1	124.6	154	-101.7	-83.4	0	0	0	111
54	K	26.4	Very low	29.3	Very low	203 Å²	203	163.4 Å²	163.4	88%	0.883	83%	0.826	S	S	*	*			trans	-116.9	102.9	147	-123.7	173.4	-174.4	170.8	0	108.9	D52 S56	D52-K54 PolarHBondContact O-N 3.31Å; K54-S56 PolarHBondContact O-N 2.9Å; K54-S56 VanDerWaalsContact O-N 3.13Å
55	A	31	Very low	30.5	Very low	100 Å²	100	165.4 Å²	165.4	83%	0.826	83%	0.827	S	S	*	*			trans	-66.5	110.8	-176.1	0	0	0	0	0	110.9
56	S	26.5	Very low	32	Very low	123 Å²	123	163.8 Å²	163.8	86%	0.86	82%	0.819	S	S	*	*			trans	-98.1	143.8	164.5	-166.9	0	0	0	0	109.9	K54	K54-S56 PolarHBondContact O-N 2.9Å; K54-S56 VanDerWaalsContact O-N 3.13Å
57	K	27.1	Very low	34	Very low	180 Å²	180	156.9 Å²	156.9	78%	0.783	79%	0.785	S	S	*	*			trans	-91.1	151.1	-173.3	-139.4	176.5	-175.9	173.9	0	110.4
58	N	25.7	Very low	36.5	Very low	131 Å²	131	153.7 Å²	153.7	70%	0.701	78%	0.783	S	S	*	*			trans	67.5	112.5	171.7	-43.8	-20.6	0	0	0	113.6
59	N	24.5	Very low	39.1	Very low	135 Å²	135	146.7 Å²	146.7	72%	0.722	75%	0.746	S	S	*	*				-158.8	157.4	63.4	-79.4	-40.4	0	0	0	112.1	E61	N59-E61 HydrophobicContact CB-CG 4.17Å; N59-E61 PolarHBondContact O-N 3.25Å
60	Y	28	Very low	42.1	Very low	246 Å²	246	139.7 Å²	139.7	97%	0.965	72%	0.722	S	S	*	*			trans	-79.2	64.2	160.3	-67.3	-81.9	0	0	0	110.3	T62	Y60-T62 PolarHBondContact O-N 2.97Å
61	E	29.2	Very low	44.9	Very low	167 Å²	167	133.7 Å²	133.7	78%	0.78	69%	0.693	S	S	*	*			trans	-68.5	120.4	162.1	-73.9	-161.9	99.8	0	0	108.2	N59 E63	N59-E61 HydrophobicContact CB-CG 4.17Å; N59-E61 PolarHBondContact O-N 3.25Å; E61-E63 PolarHBondContact O-N 2.93Å
62	T	36.3	Very low	47.8	Very low	127 Å²	127	132.1 Å²	132.1	78%	0.779	68%	0.682	S	S	*	*			trans	-59.2	129.8	170.2	-6.6	0	0	0	0	107.8	Y60 R64	Y60-T62 PolarHBondContact O-N 2.97Å; T62-R64 VanDerWaalsContact C-N 3.27Å; T62-R64 PolarHBondContact O-N 2.71Å
63	E	34.7	Very low	50.7	Low	191 Å²	191	127.4 Å²	127.4	89%	0.893	66%	0.656	S	S	*	*			trans	-60.6	87.3	178.8	-72.1	-175.7	100.7	0	0	111.2	E61 H65	E61-E63 PolarHBondContact O-N 2.93Å; E63-H65 PolarHBondContact O-N 3.41Å
64	R	44.6	Very low	53.6	Low	186 Å²	186	118.6 Å²	118.6	70%	0.702	62%	0.615	S	S	*	*			trans	-71.5	106.6	162.4	-67.8	178.2	177.5	-176.2	0.7	105.8	T62 Q66	T62-R64 VanDerWaalsContact C-N 3.27Å; T62-R64 PolarHBondContact O-N 2.71Å; R64-Q66 PolarHBondContact O-N 3.24Å
65	H	53.3	Low	56.8	Low	170 Å²	170	110.4 Å²	110.4	79%	0.787	58%	0.58	S	S	*	*			trans	-43.9	109.2	165.5	-73.6	-77.5	0	0	0	108.7	E63 G67	E63-H65 PolarHBondContact O-N 3.41Å; H65-G67 PolarHBondContact O-N 3.2Å; H65-G67 VanDerWaalsContact O-N 3.12Å
66	Q	58.8	Low	59.5	Low	147 Å²	147	110.1 Å²	110.1	69%	0.687	56%	0.561	S	S	*	*			trans	-78.1	108.7	-171	-170.9	168	3.5	0	0	108.2	R64 S68 D303	R64-Q66 PolarHBondContact O-N 3.24Å; Q66-S68 PolarHBondContact O-N 3.38Å; Q66-D303 PolarHBondContact NE2-OD1 3.14Å
67	G	70.7	Confident	62.5	Low	13 Å²	13	105.5 Å²	105.5	13%	0.134	53%	0.526	C	S	.	.			trans	-48	130.6	-177.6	0	0	0	0	0	112.6	H65 E300 K302	H65-G67 PolarHBondContact O-N 3.2Å; H65-G67 VanDerWaalsContact O-N 3.12Å; G67-E300 CarbonylContact C-O 3.21Å; G67-E300 WeakPolarHBondContact CA-O 3.35Å; G67-K302 WeakPolarHBondContact O-CA 3.36Å; G67-K302 VanDerWaalsContact O-CB 3.28Å; G67-K302 WeakPolarHBondContact O-CB 3.23Å
68	S	79.4	Confident	65.5	Low	114 Å²	114	96.9 Å²	96.9	80%	0.797	49%	0.489	S	S	*	.			trans	-90.9	-17.5	-179.7	55.9	0	0	0	0	113	Q66 E300	Q66-S68 PolarHBondContact O-N 3.38Å; S68-E300 PolarHBondContact N-O 2.95Å
69	S	83.1	Confident	68.6	Low	7 Å²	7	90.8 Å²	90.8	5%	0.049	46%	0.457	C	S	.	.	B	Isolated β-bridge	trans	-71	132	-172.7	-172.6	0	0	0	0	112.1	S74 E300 K302	S69-S74 PolarHBondContact OG-OG 3.25Å; S69-E300 VanDerWaalsContact CB-O 3.26Å; S69-E300 WeakPolarHBondContact CB-O 3.49Å; S69-E300 PolarHBondContact N-O 3.33Å; S69-K302 VanDerWaalsContact O-CB 3.27Å; S69-K302 WeakPolarHBondContact O-CB 3.28Å; S69-K302 PolarHBondContact O-N 2.91Å
70	S	89.8	Confident	71.6	Confident	58 Å²	58	84.7 Å²	84.7	41%	0.406	42%	0.424	S	S	.	.			trans	-76.9	159.3	176	75.2	0	0	0	0	111.5	S72 M73 S74	S70-S72 VanDerWaalsContact C-N 3.25Å; S70-S72 PolarHBondContact O-N 3.4Å; S70-M73 PolarHBondContact O-N 2.88Å; S70-M73 WeakPolarHBondContact OG-CB 3.27Å; S70-M73 PolarHBondContact OG-N 3.08Å; S70-M73 VanDerWaalsContact OG-N 3.08Å; S70-S74 WeakPolarHBondContact O-CB 3.5Å; S70-S74 PolarHBondContact O-N 2.88Å; S70-S74 PolarHBondContact O-OG 3.5Å
71	V	90.8	Very high	74.6	Confident	55 Å²	55	74.3 Å²	74.3	33%	0.333	39%	0.389	S	S	.	.	H	α-helix	trans	-56.8	-41.2	174.9	175	0	0	0	0	111	S74 I75 L301 V312	V71-S74 PolarHBondContact O-N 3.01Å; V71-I75 HydrophobicContact CG1-CD1 4.11Å; V71-I75 WeakPolarHBondContact O-CG1 3.49Å; V71-I75 PolarHBondContact O-N 3.15Å; V71-L301 HydrophobicContact CG2-CD1 4.26Å; V71-V312 HydrophobicContact CG1-CG2 3.88Å
72	S	89.3	Confident	77.6	Confident	72 Å²	72	66.6 Å²	66.6	50%	0.503	35%	0.353	S	S	.	.	H	α-helix	trans	-68.7	-42.8	179	-46.7	0	0	0	0	112.5	S70 S74 I75 F76	S70-S72 VanDerWaalsContact C-N 3.25Å; S70-S72 PolarHBondContact O-N 3.4Å; S72-S74 VanDerWaalsContact C-N 3.31Å; S72-S74 PolarHBondContact O-N 3.32Å; S72-I75 PolarHBondContact O-N 3.49Å; S72-F76 WeakPolarHBondContact O-CD2 3.39Å; S72-F76 PolarHBondContact O-N 3.36Å
73	M	87.8	Confident	80	Confident	65 Å²	65	60.7 Å²	60.7	32%	0.32	32%	0.317	S	S	.	.	H	α-helix	trans	-64.2	-38.6	175.2	-173.9	170.4	-76.2	0	0	111.3	S70 I75 F76 N77	S70-M73 PolarHBondContact O-N 2.88Å; S70-M73 WeakPolarHBondContact OG-CB 3.27Å; S70-M73 PolarHBondContact OG-N 3.08Å; S70-M73 VanDerWaalsContact OG-N 3.08Å; M73-I75 PolarHBondContact O-N 2.95Å; M73-F76 PolarHBondContact O-N 2.93Å; M73-N77 WeakPolarHBondContact O-CB 3.43Å; M73-N77 VanDerWaalsContact O-CG 3.24Å; M73-N77 PolarHBondContact O-N 2.73Å; M73-N77 PolarHBondContact O-OD1 3.06Å
74	S	89.8	Confident	82.2	Confident	0 Å²	0	52.1 Å²	52.1	0%	0	28%	0.279	C	S	.	.	H	α-helix	trans	-63.3	-38.3	173.2	-55.3	0	0	0	0	112.2	S69 S70 V71 S72 L78 L301	S69-S74 PolarHBondContact OG-OG 3.25Å; S70-S74 WeakPolarHBondContact O-CB 3.5Å; S70-S74 PolarHBondContact O-N 2.88Å; S70-S74 PolarHBondContact O-OG 3.5Å; V71-S74 PolarHBondContact O-N 3.01Å; S72-S74 VanDerWaalsContact C-N 3.31Å; S72-S74 PolarHBondContact O-N 3.32Å; S74-L78 VanDerWaalsContact O-CB 3.22Å; S74-L78 WeakPolarHBondContact O-CB 3.47Å; S74-L78 PolarHBondContact O-N 2.9Å; S74-L301 WeakPolarHBondContact OG-CD1 3.43Å
75	I	91.9	Very high	83.9	Confident	31 Å²	31	43.3 Å²	43.3	16%	0.159	25%	0.247	C	C	.	.	H	α-helix	trans	-63.5	-44.1	173.8	-71.7	162.2	0	0	0	110.9	V71 S72 M73 L78 S79 V312 V315 S316	V71-I75 HydrophobicContact CG1-CD1 4.11Å; V71-I75 WeakPolarHBondContact O-CG1 3.49Å; V71-I75 PolarHBondContact O-N 3.15Å; S72-I75 PolarHBondContact O-N 3.49Å; M73-I75 PolarHBondContact O-N 2.95Å; I75-L78 PolarHBondContact O-N 3.46Å; I75-S79 VanDerWaalsContact O-CB 3.26Å; I75-S79 WeakPolarHBondContact O-CB 3.37Å; I75-S79 PolarHBondContact O-N 3.31Å; I75-S79 PolarHBondContact O-OG 3.4Å; I75-V312 HydrophobicContact CG1-CB 4.22Å; I75-V312 HydrophobicContact CG1-CG1 3.98Å; I75-V312 HydrophobicContact CG1-CG2 4.2Å; I75-V315 HydrophobicContact CD1-CB 4.23Å; I75-V315 HydrophobicContact CD1-CG1 4.04Å; I75-V315 HydrophobicContact CG1-CG1 4.48Å; I75-V315 HydrophobicContact CG2-CG1 4.13Å; I75-S316 PolarHBondContact O-OG 3.1Å
76	F	88.9	Confident	85.5	Confident	94 Å²	94	35.3 Å²	35.3	41%	0.412	21%	0.21	S	C	.	.	H	α-helix	trans	-65.3	-47.9	178.1	-65.5	-49.4	0	0	0	112.1	S72 M73 L78 S79 I80 L222	S72-F76 WeakPolarHBondContact O-CD2 3.39Å; S72-F76 PolarHBondContact O-N 3.36Å; M73-F76 PolarHBondContact O-N 2.93Å; F76-L78 VanDerWaalsContact C-N 3.33Å; F76-L78 PolarHBondContact O-N 3.31Å; F76-S79 PolarHBondContact O-N 3.38Å; F76-I80 VanDerWaalsContact O-CD1 3.32Å; F76-I80 WeakPolarHBondContact O-CD1 3.23Å; F76-I80 WeakPolarHBondContact O-CG1 3.32Å; F76-I80 PolarHBondContact O-N 2.99Å; F76-I80 VanDerWaalsContact O-N 3.14Å; F76-L222 HydrophobicContact CD1-CD2 3.56Å; F76-L222 HydrophobicContact CE1-CD2 4.01Å
77	N	88.2	Confident	87	Confident	26 Å²	26	28.4 Å²	28.4	14%	0.139	18%	0.178	C	C	.	.	H	α-helix	trans	-60.5	-41.6	177.3	-66.6	4.8	0	0	0	111.5	M73 I80 A81 S218 M297	M73-N77 WeakPolarHBondContact O-CB 3.43Å; M73-N77 VanDerWaalsContact O-CG 3.24Å; M73-N77 PolarHBondContact O-N 2.73Å; M73-N77 PolarHBondContact O-OD1 3.06Å; N77-I80 PolarHBondContact O-N 2.67Å; N77-A81 PolarHBondContact O-N 2.74Å; N77-A81 VanDerWaalsContact O-N 3.14Å; N77-S218 WeakPolarHBondContact OD1-CB 3.37Å; N77-S218 PolarHBondContact OD1-OG 3.48Å; N77-S218 VanDerWaalsContact OD1-OG 3.12Å; N77-M297 HydrophobicContact CB-CE 3.73Å; N77-M297 HydrophobicContact CB-SD 4.26Å
78	L	91	Very high	88	Confident	0 Å²	0	27.8 Å²	27.8	0%	0	17%	0.171	C	C	.	.	H	α-helix	trans	-71.8	-37.8	179	-168.5	62.3	0	0	0	112.4	S74 I75 F76 I80 A81 I82 C290 I294 M297 V312 A313	S74-L78 VanDerWaalsContact O-CB 3.22Å; S74-L78 WeakPolarHBondContact O-CB 3.47Å; S74-L78 PolarHBondContact O-N 2.9Å; I75-L78 PolarHBondContact O-N 3.46Å; F76-L78 VanDerWaalsContact C-N 3.33Å; F76-L78 PolarHBondContact O-N 3.31Å; L78-I80 VanDerWaalsContact C-N 3.26Å; L78-I80 PolarHBondContact O-N 2.94Å; L78-A81 PolarHBondContact O-N 2.94Å; L78-I82 HydrophobicContact CG-CD1 4.29Å; L78-I82 WeakPolarHBondContact O-CG1 3.48Å; L78-I82 PolarHBondContact O-N 3.49Å; L78-C290 HydrophobicContact CD1-CB 3.68Å; L78-I294 HydrophobicContact CD1-CG1 4.29Å; L78-M297 HydrophobicContact CB-CE 4.01Å; L78-M297 HydrophobicContact CB-SD 3.74Å; L78-M297 HydrophobicContact CD1-CE 4.15Å; L78-M297 HydrophobicContact CD1-SD 4.32Å; L78-V312 HydrophobicContact CB-CG1 4.37Å; L78-V312 HydrophobicContact CD2-CG1 3.89Å; L78-A313 HydrophobicContact CD2-CB 4.14Å
79	S	91.6	Very high	88.6	Confident	3 Å²	3	22.3 Å²	22.3	2%	0.021	13%	0.133	C	C	.	.	H	α-helix	trans	-57.7	-41.6	174.8	-63.1	0	0	0	0	111	I75 F76 I82 M83 M320	I75-S79 VanDerWaalsContact O-CB 3.26Å; I75-S79 WeakPolarHBondContact O-CB 3.37Å; I75-S79 PolarHBondContact O-N 3.31Å; I75-S79 PolarHBondContact O-OG 3.4Å; F76-S79 PolarHBondContact O-N 3.38Å; S79-I82 PolarHBondContact O-N 3.48Å; S79-M83 WeakPolarHBondContact O-CB 3.3Å; S79-M83 PolarHBondContact O-N 3.38Å; S79-M320 VanDerWaalsContact O-SD 3.42Å
80	I	87.6	Confident	89.2	Confident	6 Å²	6	22 Å²	22	3%	0.031	13%	0.131	C	C	.	.	H	α-helix	trans	-71.3	-40.1	179.1	-64.7	156.1	0	0	0	112	F76 N77 L78 I82 M83 G84 S218 L222 T371	F76-I80 VanDerWaalsContact O-CD1 3.32Å; F76-I80 WeakPolarHBondContact O-CD1 3.23Å; F76-I80 WeakPolarHBondContact O-CG1 3.32Å; F76-I80 PolarHBondContact O-N 2.99Å; F76-I80 VanDerWaalsContact O-N 3.14Å; N77-I80 PolarHBondContact O-N 2.67Å; L78-I80 VanDerWaalsContact C-N 3.26Å; L78-I80 PolarHBondContact O-N 2.94Å; I80-I82 PolarHBondContact O-N 3.45Å; I80-M83 HydrophobicContact CB-CE 4.46Å; I80-M83 HydrophobicContact CG1-CE 3.93Å; I80-M83 PolarHBondContact O-N 2.85Å; I80-G84 PolarHBondContact O-N 2.96Å; I80-G84 VanDerWaalsContact O-N 3.12Å; I80-S218 VanDerWaalsContact CD1-C 3.48Å; I80-S218 WeakPolarHBondContact CD1-O 3.47Å; I80-L222 HydrophobicContact CD1-CB 4.49Å; I80-L222 HydrophobicContact CG1-CB 4.37Å; I80-T371 HydrophobicContact CG2-CG2 3.87Å
81	A	89	Confident	89.5	Confident	29 Å²	29	19.2 Å²	19.2	24%	0.24	11%	0.112	C	C	.	.	H	α-helix	trans	-65.3	-20	174.3	0	0	0	0	0	113.7	N77 L78 C290 T293	N77-A81 PolarHBondContact O-N 2.74Å; N77-A81 VanDerWaalsContact O-N 3.14Å; L78-A81 PolarHBondContact O-N 2.94Å; A81-C290 HydrophobicContact CB-CB 4.47Å; A81-T293 HydrophobicContact CB-CG2 4.3Å; A81-T293 WeakPolarHBondContact CB-OG1 3.41Å
82	I	92.4	Very high	89.7	Confident	5 Å²	5	17 Å²	17	3%	0.026	10%	0.097	C	C	.	.	H	α-helix	trans	-83.2	-61.5	167.3	-65.4	165.2	0	0	0	109.4	L78 S79 I80 G84 A287 F288 C290 F317 M320 Y324	L78-I82 HydrophobicContact CG-CD1 4.29Å; L78-I82 WeakPolarHBondContact O-CG1 3.48Å; L78-I82 PolarHBondContact O-N 3.49Å; S79-I82 PolarHBondContact O-N 3.48Å; I80-I82 PolarHBondContact O-N 3.45Å; I82-G84 PolarHBondContact O-N 2.87Å; I82-A287 VanDerWaalsContact O-O 3.05Å; I82-F288 HydrophobicContact CG2-CD1 3.9Å; I82-F288 HydrophobicContact CG2-CE1 4.39Å; I82-C290 HydrophobicContact CG1-CB 3.69Å; I82-F317 HydrophobicContact CD1-CD1 4.23Å; I82-F317 HydrophobicContact CD1-CD2 3.75Å; I82-F317 HydrophobicContact CD1-CE1 4.27Å; I82-F317 HydrophobicContact CD1-CE2 3.82Å; I82-F317 HydrophobicContact CD1-CG 3.97Å; I82-F317 HydrophobicContact CD1-CZ 4.08Å; I82-F317 HydrophobicContact CG1-CE2 4.49Å; I82-F317 HydrophobicContact CG1-CZ 4.37Å; I82-M320 HydrophobicContact CB-CB 4.47Å; I82-M320 HydrophobicContact CB-CG 3.96Å; I82-M320 HydrophobicContact CD1-CG 4.36Å; I82-M320 HydrophobicContact CG2-CB 3.7Å; I82-M320 HydrophobicContact CG2-CG 3.73Å; I82-Y324 VanDerWaalsContact C-OH 3.3Å; I82-Y324 HydrophobicContact CG2-CE2 4.24Å; I82-Y324 PolarHBondContact O-OH 2.9Å
83	M	87.9	Confident	90	Very high	2 Å²	2	13.6 Å²	13.6	1%	0.01	7%	0.074	C	C	.	.	H	α-helix	trans	-47.9	-52.6	-170.3	-173.3	169.5	59.5	0	0	114.2	S79 I80 G86 L222 M225 M320 M323 Y324	S79-M83 WeakPolarHBondContact O-CB 3.3Å; S79-M83 PolarHBondContact O-N 3.38Å; I80-M83 HydrophobicContact CB-CE 4.46Å; I80-M83 HydrophobicContact CG1-CE 3.93Å; I80-M83 PolarHBondContact O-N 2.85Å; M83-G86 PolarHBondContact O-N 3.38Å; M83-L222 HydrophobicContact CE-CD1 3.91Å; M83-L222 HydrophobicContact SD-CD1 3.77Å; M83-M225 HydrophobicContact CE-CB 3.8Å; M83-M225 HydrophobicContact CE-CG 3.57Å; M83-M225 HydrophobicContact CG-CB 4.48Å; M83-M225 HydrophobicContact CG-CG 4.39Å; M83-M225 HydrophobicContact SD-CB 3.29Å; M83-M225 WeakPolarHBondContact SD-CB 3.25Å; M83-M225 HydrophobicContact SD-CG 3.59Å; M83-M225 VanDerWaalsContact SD-CG 3.59Å; M83-M320 HydrophobicContact CB-SD 3.72Å; M83-M320 HydrophobicContact CG-SD 4.19Å; M83-M320 HydrophobicContact SD-SD 4.25Å; M83-M323 HydrophobicContact SD-CE 3.88Å; M83-Y324 WeakPolarHBondContact CA-OH 3.07Å; M83-Y324 PolarHBondContact N-OH 3.38Å; M83-Y324 PolarHBondContact O-OH 3.25Å
84	G	79.4	Confident	90.4	Very high	11 Å²	11	10.5 Å²	10.5	11%	0.113	6%	0.059	C	C	.	.	T	Hydrogen-bonded Turn	trans	30.2	-133.3	-177.8	0	0	0	0	0	116.5	I80 I82 Y163	I80-G84 PolarHBondContact O-N 2.96Å; I80-G84 VanDerWaalsContact O-N 3.12Å; I82-G84 PolarHBondContact O-N 2.87Å; G84-Y163 WeakPolarHBondContact CA-OH 3.1Å
85	S	82.3	Confident	90.6	Very high	2 Å²	2	11 Å²	11	1%	0.014	6%	0.063	C	C	.	.	T	Hydrogen-bonded Turn	trans	-91.6	-9.4	172.5	66.7	0	0	0	0	112.8	I87 L88 T162	S85-I87 PolarHBondContact O-N 3.34Å; S85-L88 PolarHBondContact O-N 3.47Å; S85-T162 WeakPolarHBondContact CB-OG1 3.38Å; S85-T162 WeakPolarHBondContact OG-CB 3.45Å; S85-T162 PolarHBondContact OG-OG1 2.84Å
86	G	85.3	Confident	90.7	Very high	2 Å²	2	10.1 Å²	10.1	2%	0.021	6%	0.059	C	C	.	.	T	Hydrogen-bonded Turn	trans	-59.6	-36.5	-171.2	0	0	0	0	0	112	M83 L88 G89 L90	M83-G86 PolarHBondContact O-N 3.38Å; G86-L88 PolarHBondContact O-N 3.34Å; G86-L88 VanDerWaalsContact O-N 3.13Å; G86-G89 PolarHBondContact O-N 3.1Å; G86-L90 WeakPolarHBondContact O-CG 3.37Å
87	I	91.8	Very high	91	Very high	1 Å²	1	5.7 Å²	5.7	1%	0.005	4%	0.039	C	C	.	.	H	α-helix	trans	-50.7	-35.6	178.1	-164.4	170.9	0	0	0	114.1	S85 G89 L90 F228 Y324 A327	S85-I87 PolarHBondContact O-N 3.34Å; I87-G89 VanDerWaalsContact C-N 3.31Å; I87-G89 PolarHBondContact O-N 3.09Å; I87-L90 PolarHBondContact O-N 3.41Å; I87-F228 HydrophobicContact CD1-CD1 4.3Å; I87-F228 HydrophobicContact CD1-CE1 4.11Å; I87-F228 HydrophobicContact CG1-CE1 4.2Å; I87-Y324 HydrophobicContact CB-CD1 4.28Å; I87-Y324 HydrophobicContact CB-CE1 3.97Å; I87-Y324 HydrophobicContact CD1-CD1 4.3Å; I87-Y324 HydrophobicContact CG1-CD1 4.1Å; I87-Y324 HydrophobicContact CG1-CE1 4.28Å; I87-A327 HydrophobicContact CD1-CB 3.95Å; I87-A327 HydrophobicContact CG1-CB 3.82Å
88	L	90.3	Very high	91.3	Very high	0 Å²	0	4.4 Å²	4.4	0%	0	3%	0.032	C	C	.	.	H	α-helix	trans	-73.8	-19.3	-177.4	-59.1	-178.4	0	0	0	113.8	S85 G86 I166 F228 E342 L343 V364	S85-L88 PolarHBondContact O-N 3.47Å; G86-L88 PolarHBondContact O-N 3.34Å; G86-L88 VanDerWaalsContact O-N 3.13Å; L88-I166 HydrophobicContact CD1-CD1 3.47Å; L88-I166 VanDerWaalsContact CD1-CD1 3.47Å; L88-I166 HydrophobicContact CD1-CG1 3.78Å; L88-F228 HydrophobicContact CD2-CE1 4.05Å; L88-F228 HydrophobicContact CD2-CE2 3.68Å; L88-F228 HydrophobicContact CD2-CZ 3.41Å; L88-F228 VanDerWaalsContact CD2-CZ 3.41Å; L88-E342 HydrophobicContact CB-CG 4.48Å; L88-L343 PolarHBondContact O-N 3.49Å; L88-L343 VanDerWaalsContact O-N 3.16Å; L88-V364 HydrophobicContact CD1-CG1 4.49Å
89	G	92.4	Very high	91.5	Very high	0 Å²	0	5.7 Å²	5.7	0%	0	4%	0.039	C	C	.	.	H	α-helix	trans	-96.6	-6.1	175.8	0	0	0	0	0	114.4	G86 I87 F92 A93	G86-G89 PolarHBondContact O-N 3.1Å; I87-G89 VanDerWaalsContact C-N 3.31Å; I87-G89 PolarHBondContact O-N 3.09Å; G89-F92 WeakPolarHBondContact O-CB 3.4Å; G89-F92 PolarHBondContact O-N 2.65Å; G89-A93 PolarHBondContact O-N 3.14Å
90	L	95.7	Very high	91.8	Very high	0 Å²	0	6.8 Å²	6.8	0%	0	5%	0.048	C	C	.	.	H	α-helix	trans	-72.2	-35.6	-172.9	-66.2	179.7	0	0	0	113.7	G86 I87 F92 A93 M94 F102 I283 L284 A287 Y324 A328	G86-L90 WeakPolarHBondContact O-CG 3.37Å; I87-L90 PolarHBondContact O-N 3.41Å; L90-F92 VanDerWaalsContact C-N 3.31Å; L90-A93 PolarHBondContact O-N 3.48Å; L90-M94 PolarHBondContact O-N 3.09Å; L90-F102 HydrophobicContact CB-CE2 4.48Å; L90-F102 HydrophobicContact CB-CZ 4.09Å; L90-F102 HydrophobicContact CD2-CE2 4.48Å; L90-F102 HydrophobicContact CD2-CZ 4.25Å; L90-F102 WeakPolarHBondContact O-CE2 3.5Å; L90-I283 HydrophobicContact CD2-CG2 4.08Å; L90-L284 HydrophobicContact CD2-CD2 3.79Å; L90-A287 HydrophobicContact CD2-CB 4.13Å; L90-Y324 VanDerWaalsContact CD1-CB 3.46Å; L90-Y324 HydrophobicContact CD1-CD1 3.59Å; L90-Y324 HydrophobicContact CD1-CD2 3.79Å; L90-Y324 HydrophobicContact CD1-CE1 4.17Å; L90-Y324 HydrophobicContact CD1-CE2 4.37Å; L90-Y324 HydrophobicContact CD1-CG 3.34Å; L90-A328 HydrophobicContact CB-CB 3.83Å
91	S	95.9	Very high	92.1	Very high	0 Å²	0	8 Å²	8	0%	0	5%	0.054	C	C	.	.	H	α-helix	trans	-63.9	-38.2	173.6	51.8	0	0	0	0	111.5	M94 A95 V339	S91-M94 PolarHBondContact O-N 2.73Å; S91-A95 WeakPolarHBondContact O-CB 3.25Å; S91-A95 PolarHBondContact O-N 2.8Å; S91-V339 WeakPolarHBondContact OG-CG1 3.42Å
92	F	95.3	Very high	92.5	Very high	7 Å²	7	6.6 Å²	6.6	3%	0.031	4%	0.043	C	C	.	.	H	α-helix	trans	-65.4	-40.7	173.7	173.3	-96.9	0	0	0	112.2	G89 L90 A95 N96 Q276 I283 V339 P341 R420	G89-F92 WeakPolarHBondContact O-CB 3.4Å; G89-F92 PolarHBondContact O-N 2.65Å; L90-F92 VanDerWaalsContact C-N 3.31Å; F92-A95 PolarHBondContact O-N 3.13Å; F92-N96 VanDerWaalsContact CE2-ND2 3.3Å; F92-N96 WeakPolarHBondContact CE2-ND2 3.31Å; F92-N96 WeakPolarHBondContact CZ-ND2 3.49Å; F92-N96 PolarHBondContact O-N 2.86Å; F92-N96 PolarHBondContact O-ND2 2.8Å; F92-Q276 HydrophobicContact CZ-CB 4.23Å; F92-I283 HydrophobicContact CD1-CD1 3.76Å; F92-I283 HydrophobicContact CE1-CD1 4.15Å; F92-V339 HydrophobicContact CB-CG1 4.18Å; F92-P341 HydrophobicContact CD1-CB 4.48Å; F92-P341 HydrophobicContact CD2-CB 4.1Å; F92-P341 HydrophobicContact CE2-CB 4.17Å; F92-P341 HydrophobicContact CG-CB 4.25Å; F92-P341 HydrophobicContact CZ-CB 4.41Å; F92-R420 HydrophobicContact CE1-CB 4.47Å
93	A	95.9	Very high	92.8	Very high	1 Å²	1	8.7 Å²	8.7	1%	0.008	6%	0.056	C	C	.	.	H	α-helix	trans	-62	-43.9	172	0	0	0	0	0	111.2	G89 L90 N96 T97 F102 A280 I283	G89-A93 PolarHBondContact O-N 3.14Å; L90-A93 PolarHBondContact O-N 3.48Å; A93-N96 PolarHBondContact O-N 3.39Å; A93-T97 WeakPolarHBondContact O-CG2 3.33Å; A93-T97 PolarHBondContact O-N 2.97Å; A93-T97 VanDerWaalsContact O-N 3.1Å; A93-T97 PolarHBondContact O-OG1 2.87Å; A93-T97 VanDerWaalsContact O-OG1 3.12Å; A93-F102 HydrophobicContact CB-CD2 4.24Å; A93-F102 HydrophobicContact CB-CE2 3.92Å; A93-A280 HydrophobicContact CB-CB 4.14Å; A93-I283 HydrophobicContact CB-CB 4.39Å; A93-I283 HydrophobicContact CB-CD1 4.16Å; A93-I283 HydrophobicContact CB-CG2 4.19Å
94	M	96.4	Very high	93.2	Very high	0 Å²	0	13.1 Å²	13.1	0%	0	8%	0.079	C	C	.	.	H	α-helix	trans	-62.9	-42.7	176.1	-174.9	179.9	-72.6	0	0	112.5	L90 S91 N96 T97 G98 I99 F102 A328 L329 Y332	L90-M94 PolarHBondContact O-N 3.09Å; S91-M94 PolarHBondContact O-N 2.73Å; M94-N96 PolarHBondContact O-N 2.75Å; M94-T97 PolarHBondContact O-N 3.21Å; M94-T97 PolarHBondContact O-OG1 3.29Å; M94-G98 WeakPolarHBondContact O-CA 3.37Å; M94-G98 PolarHBondContact O-N 3.37Å; M94-I99 HydrophobicContact SD-CG1 4.09Å; M94-F102 HydrophobicContact CB-CB 4.06Å; M94-F102 HydrophobicContact CB-CD1 4.28Å; M94-F102 HydrophobicContact CB-CD2 3.69Å; M94-F102 HydrophobicContact CB-CE2 4.19Å; M94-F102 HydrophobicContact CB-CG 3.73Å; M94-F102 HydrophobicContact CE-CB 4.19Å; M94-F102 HydrophobicContact CE-CD1 3.21Å; M94-F102 HydrophobicContact CE-CE1 3.69Å; M94-F102 HydrophobicContact CE-CG 3.8Å; M94-F102 HydrophobicContact CG-CB 3.86Å; M94-F102 HydrophobicContact CG-CD1 4.38Å; M94-F102 HydrophobicContact CG-CD2 4.42Å; M94-F102 HydrophobicContact CG-CG 3.96Å; M94-A328 HydrophobicContact CE-CB 3.8Å; M94-L329 HydrophobicContact CE-CB 4.1Å; M94-L329 HydrophobicContact CE-CD1 4.34Å; M94-L329 HydrophobicContact SD-CB 4.47Å; M94-L329 HydrophobicContact SD-CD1 4.13Å; M94-Y332 HydrophobicContact CB-CG 4.5Å; M94-Y332 HydrophobicContact CG-CD1 4.08Å; M94-Y332 HydrophobicContact CG-CG 3.95Å; M94-Y332 VanDerWaalsContact SD-CB 3.55Å; M94-Y332 HydrophobicContact SD-CD1 3.68Å; M94-Y332 HydrophobicContact SD-CG 3.81Å
95	A	94.3	Very high	94.1	Very high	11 Å²	11	14.3 Å²	14.3	9%	0.091	8%	0.082	C	C	.	.	H	α-helix	trans	-58.6	-35.3	177.4	0	0	0	0	0	112.7	S91 F92 Y332 V339	S91-A95 WeakPolarHBondContact O-CB 3.25Å; S91-A95 PolarHBondContact O-N 2.8Å; F92-A95 PolarHBondContact O-N 3.13Å; A95-Y332 HydrophobicContact CB-CD2 3.79Å; A95-Y332 HydrophobicContact CB-CE2 4.02Å; A95-V339 HydrophobicContact CB-CB 3.98Å; A95-V339 HydrophobicContact CB-CG2 4.11Å
96	N	93.5	Very high	94.8	Very high	13 Å²	13	14.2 Å²	14.2	7%	0.07	8%	0.082	C	C	.	.	H	α-helix	trans	-93.5	-3.9	-177.7	-70.3	-64.7	0	0	0	114.9	F92 A93 M94 N274 Q276 T277	F92-N96 VanDerWaalsContact CE2-ND2 3.3Å; F92-N96 WeakPolarHBondContact CE2-ND2 3.31Å; F92-N96 WeakPolarHBondContact CZ-ND2 3.49Å; F92-N96 PolarHBondContact O-N 2.86Å; F92-N96 PolarHBondContact O-ND2 2.8Å; A93-N96 PolarHBondContact O-N 3.39Å; M94-N96 PolarHBondContact O-N 2.75Å; N96-N274 PolarHBondContact OD1-ND2 3.19Å; N96-N274 PolarHBondContact OD1-OD1 3.39Å; N96-Q276 HydrophobicContact CB-CB 4.16Å; N96-Q276 PolarHBondContact ND2-OE1 3.33Å; N96-Q276 WeakPolarHBondContact OD1-CB 3.23Å; N96-T277 WeakPolarHBondContact O-CB 3.48Å; N96-T277 PolarHBondContact O-OG1 3.48Å
97	T	95	Very high	95.4	Very high	0 Å²	0	16.6 Å²	16.6	0%	0	10%	0.096	C	C	.	.	H	α-helix	trans	-113	-21.2	170.9	58.2	0	0	0	0	113.5	A93 M94 L101 F102 L105 F271 V272 T277 A280	A93-T97 WeakPolarHBondContact O-CG2 3.33Å; A93-T97 PolarHBondContact O-N 2.97Å; A93-T97 VanDerWaalsContact O-N 3.1Å; A93-T97 PolarHBondContact O-OG1 2.87Å; A93-T97 VanDerWaalsContact O-OG1 3.12Å; M94-T97 PolarHBondContact O-N 3.21Å; M94-T97 PolarHBondContact O-OG1 3.29Å; T97-L101 HydrophobicContact CG2-CD2 4.23Å; T97-L101 HydrophobicContact CG2-CG 4.33Å; T97-L101 WeakPolarHBondContact O-CB 3.31Å; T97-F102 WeakPolarHBondContact OG1-CB 3.29Å; T97-F102 PolarHBondContact OG1-N 2.89Å; T97-L105 HydrophobicContact CG2-CD1 4.02Å; T97-F271 CarbonylContact O-C 3.54Å; T97-F271 WeakPolarHBondContact O-CA 3.5Å; T97-V272 CarbonylContact C-O 3.2Å; T97-V272 WeakPolarHBondContact CA-O 3.42Å; T97-V272 PolarHBondContact O-N 3.37Å; T97-T277 HydrophobicContact CG2-CG2 4.04Å; T97-A280 HydrophobicContact CG2-CB 3.41Å; T97-A280 VanDerWaalsContact CG2-CB 3.41Å
98	G	94.7	Very high	95.6	Very high	0 Å²	0	18.9 Å²	18.9	0%	0	11%	0.11	C	C	.	.			trans	75	162.8	-160.2	0	0	0	0	0	112.7	M94 A100 F102 K269 Y270	M94-G98 WeakPolarHBondContact O-CA 3.37Å; M94-G98 PolarHBondContact O-N 3.37Å; G98-A100 PolarHBondContact O-N 3.33Å; G98-F102 WeakPolarHBondContact O-CB 3.42Å; G98-F102 PolarHBondContact O-N 3.45Å; G98-K269 CarbonylContact C-O 3.58Å; G98-K269 WeakPolarHBondContact CA-O 3.33Å; G98-Y270 CarbonylContact C-O 3.31Å; G98-Y270 VanDerWaalsContact C-O 3.31Å
99	I	96	Very high	96	Very high	26 Å²	26	19.2 Å²	19.2	13%	0.133	11%	0.112	C	C	.	.	H	α-helix	trans	-60.8	-48.3	-170.9	-57.2	-179.9	0	0	0	112.4	M94 F102 V103 P268 K269 Y270 L329 Y332 L333	M94-I99 HydrophobicContact SD-CG1 4.09Å; I99-F102 PolarHBondContact O-N 2.9Å; I99-V103 HydrophobicContact CG2-CG2 4.4Å; I99-V103 WeakPolarHBondContact O-CG2 3.49Å; I99-V103 PolarHBondContact O-N 3.01Å; I99-P268 HydrophobicContact CD1-CB 3.85Å; I99-K269 PolarHBondContact N-O 2.66Å; I99-Y270 PolarHBondContact N-O 2.9Å; I99-L329 HydrophobicContact CD1-CD1 4.1Å; I99-L329 HydrophobicContact CG2-CD1 4.2Å; I99-Y332 HydrophobicContact CD1-CD1 4.1Å; I99-Y332 HydrophobicContact CD1-CE1 3.84Å; I99-Y332 HydrophobicContact CG1-CD1 3.82Å; I99-Y332 HydrophobicContact CG1-CE1 3.58Å; I99-L333 HydrophobicContact CD1-CD2 4.26Å
100	A	95.9	Very high	96.2	Very high	26 Å²	26	19.6 Å²	19.6	22%	0.215	12%	0.115	C	C	.	.	H	α-helix	trans	-67.5	-45.3	-171.9	0	0	0	0	0	111.5	G98 V103 I104 Y270 F271	G98-A100 PolarHBondContact O-N 3.33Å; A100-V103 PolarHBondContact O-N 3.28Å; A100-I104 WeakPolarHBondContact O-CD1 3.37Å; A100-I104 VanDerWaalsContact O-CG1 3.31Å; A100-I104 WeakPolarHBondContact O-CG1 3.41Å; A100-I104 PolarHBondContact O-N 2.91Å; A100-I104 VanDerWaalsContact O-N 3.12Å; A100-Y270 HydrophobicContact CB-CD1 4.4Å; A100-Y270 WeakPolarHBondContact CB-O 3.36Å; A100-Y270 PolarHBondContact N-O 3.31Å; A100-F271 HydrophobicContact CB-CE1 4Å; A100-F271 HydrophobicContact CB-CE2 4.08Å; A100-F271 HydrophobicContact CB-CZ 3.72Å
101	L	95.6	Very high	96.2	Very high	31 Å²	31	24.4 Å²	24.4	16%	0.162	14%	0.14	C	C	.	.	H	α-helix	trans	-66.2	-38.1	175.9	-178.9	59.3	0	0	0	111.6	T97 I104 L105 F271 F273	T97-L101 HydrophobicContact CG2-CD2 4.23Å; T97-L101 HydrophobicContact CG2-CG 4.33Å; T97-L101 WeakPolarHBondContact O-CB 3.31Å; L101-I104 PolarHBondContact O-N 2.92Å; L101-L105 HydrophobicContact CD1-CD1 4.16Å; L101-L105 HydrophobicContact CD1-CG 4.12Å; L101-L105 HydrophobicContact CG-CD1 4.01Å; L101-L105 HydrophobicContact CG-CG 4.41Å; L101-L105 WeakPolarHBondContact O-CB 3.39Å; L101-L105 VanDerWaalsContact O-CG 3.28Å; L101-L105 WeakPolarHBondContact O-CG 3.32Å; L101-L105 PolarHBondContact O-N 3.46Å; L101-F271 HydrophobicContact CB-CD1 4.09Å; L101-F271 HydrophobicContact CB-CE1 4.38Å; L101-F273 HydrophobicContact CD2-CD1 4.46Å; L101-F273 HydrophobicContact CD2-CE1 3.67Å; L101-F273 HydrophobicContact CD2-CZ 3.89Å
102	F	97.4	Very high	96.3	Very high	0 Å²	0	27 Å²	27	0%	0	15%	0.151	C	C	.	.	H	α-helix	trans	-58.8	-49.5	174.3	-176	-94.8	0	0	0	112	L90 A93 M94 T97 G98 I99 I104 L105 L106 L284 A328	L90-F102 HydrophobicContact CB-CE2 4.48Å; L90-F102 HydrophobicContact CB-CZ 4.09Å; L90-F102 HydrophobicContact CD2-CE2 4.48Å; L90-F102 HydrophobicContact CD2-CZ 4.25Å; L90-F102 WeakPolarHBondContact O-CE2 3.5Å; A93-F102 HydrophobicContact CB-CD2 4.24Å; A93-F102 HydrophobicContact CB-CE2 3.92Å; M94-F102 HydrophobicContact CB-CB 4.06Å; M94-F102 HydrophobicContact CB-CD1 4.28Å; M94-F102 HydrophobicContact CB-CD2 3.69Å; M94-F102 HydrophobicContact CB-CE2 4.19Å; M94-F102 HydrophobicContact CB-CG 3.73Å; M94-F102 HydrophobicContact CE-CB 4.19Å; M94-F102 HydrophobicContact CE-CD1 3.21Å; M94-F102 HydrophobicContact CE-CE1 3.69Å; M94-F102 HydrophobicContact CE-CG 3.8Å; M94-F102 HydrophobicContact CG-CB 3.86Å; M94-F102 HydrophobicContact CG-CD1 4.38Å; M94-F102 HydrophobicContact CG-CD2 4.42Å; M94-F102 HydrophobicContact CG-CG 3.96Å; T97-F102 WeakPolarHBondContact OG1-CB 3.29Å; T97-F102 PolarHBondContact OG1-N 2.89Å; G98-F102 WeakPolarHBondContact O-CB 3.42Å; G98-F102 PolarHBondContact O-N 3.45Å; I99-F102 PolarHBondContact O-N 2.9Å; F102-I104 VanDerWaalsContact C-N 3.32Å; F102-I104 PolarHBondContact O-N 3.46Å; F102-L105 PolarHBondContact O-N 2.89Å; F102-L106 HydrophobicContact CD1-CB 4.4Å; F102-L106 HydrophobicContact CE1-CB 4.16Å; F102-L106 HydrophobicContact CE1-CD1 4.11Å; F102-L106 HydrophobicContact CE1-CD2 3.98Å; F102-L106 HydrophobicContact CE1-CG 4.31Å; F102-L106 HydrophobicContact CZ-CD1 4.07Å; F102-L106 VanDerWaalsContact O-CB 3.27Å; F102-L106 WeakPolarHBondContact O-CB 3.44Å; F102-L106 PolarHBondContact O-N 3Å; F102-L284 HydrophobicContact CE2-CD2 4Å; F102-L284 HydrophobicContact CZ-CD2 4.11Å; F102-A328 HydrophobicContact CD1-CB 4.41Å; F102-A328 HydrophobicContact CE1-CB 3.52Å; F102-A328 HydrophobicContact CE2-CB 4.4Å; F102-A328 HydrophobicContact CZ-CB 3.52Å
103	V	97.8	Very high	96.4	Very high	50 Å²	50	26.7 Å²	26.7	30%	0.303	15%	0.149	S	C	.	.	H	α-helix	trans	-61.7	-41.4	-178.6	172.6	0	0	0	0	111	I99 A100 L106 V107 L325	I99-V103 HydrophobicContact CG2-CG2 4.4Å; I99-V103 WeakPolarHBondContact O-CG2 3.49Å; I99-V103 PolarHBondContact O-N 3.01Å; A100-V103 PolarHBondContact O-N 3.28Å; V103-L106 PolarHBondContact O-N 3.5Å; V103-V107 HydrophobicContact CG1-CG2 4.49Å; V103-V107 WeakPolarHBondContact O-CB 3.46Å; V103-V107 VanDerWaalsContact O-CG2 3.28Å; V103-V107 WeakPolarHBondContact O-CG2 3.3Å; V103-V107 PolarHBondContact O-N 3.11Å; V103-L325 HydrophobicContact CG2-CD1 3.78Å
104	I	97.4	Very high	96.4	Very high	95 Å²	95	28.6 Å²	28.6	49%	0.487	16%	0.159	S	C	.	.	H	α-helix	trans	-59.7	-52.2	174.6	-68.1	165	0	0	0	110.3	A100 L101 F102 L106 V107 T108	A100-I104 WeakPolarHBondContact O-CD1 3.37Å; A100-I104 VanDerWaalsContact O-CG1 3.31Å; A100-I104 WeakPolarHBondContact O-CG1 3.41Å; A100-I104 PolarHBondContact O-N 2.91Å; A100-I104 VanDerWaalsContact O-N 3.12Å; L101-I104 PolarHBondContact O-N 2.92Å; F102-I104 VanDerWaalsContact C-N 3.32Å; F102-I104 PolarHBondContact O-N 3.46Å; I104-L106 PolarHBondContact O-N 2.99Å; I104-V107 PolarHBondContact O-N 3.35Å; I104-T108 WeakPolarHBondContact O-CB 3.42Å; I104-T108 PolarHBondContact O-N 3.02Å; I104-T108 PolarHBondContact O-OG1 2.94Å; I104-T108 VanDerWaalsContact O-OG1 3.06Å
105	L	96.7	Very high	96.4	Very high	36 Å²	36	32 Å²	32	19%	0.188	17%	0.173	C	C	.	.	H	α-helix	trans	-62.8	-41.4	-179.2	-67.3	172.6	0	0	0	112.4	T97 L101 F102 T108 V109 V281 L284	T97-L105 HydrophobicContact CG2-CD1 4.02Å; L101-L105 HydrophobicContact CD1-CD1 4.16Å; L101-L105 HydrophobicContact CD1-CG 4.12Å; L101-L105 HydrophobicContact CG-CD1 4.01Å; L101-L105 HydrophobicContact CG-CG 4.41Å; L101-L105 WeakPolarHBondContact O-CB 3.39Å; L101-L105 VanDerWaalsContact O-CG 3.28Å; L101-L105 WeakPolarHBondContact O-CG 3.32Å; L101-L105 PolarHBondContact O-N 3.46Å; F102-L105 PolarHBondContact O-N 2.89Å; L105-T108 PolarHBondContact O-N 3.43Å; L105-V109 WeakPolarHBondContact O-CB 3.22Å; L105-V109 WeakPolarHBondContact O-CG2 3.24Å; L105-V109 PolarHBondContact O-N 3.44Å; L105-V281 HydrophobicContact CD1-CG2 4.38Å; L105-V281 HydrophobicContact CD2-CG2 4.12Å; L105-L284 HydrophobicContact CB-CD1 3.48Å; L105-L284 VanDerWaalsContact CB-CD1 3.48Å; L105-L284 HydrophobicContact CD1-CD1 4.46Å
106	L	97.5	Very high	96.5	Very high	0 Å²	0	31.5 Å²	31.5	0%	0	17%	0.169	C	C	.	.	H	α-helix	trans	-60	-47.8	176.7	-174.5	80.6	0	0	0	111.2	F102 V103 I104 A110 L284 F288 F321 Y324 L325	F102-L106 HydrophobicContact CD1-CB 4.4Å; F102-L106 HydrophobicContact CE1-CB 4.16Å; F102-L106 HydrophobicContact CE1-CD1 4.11Å; F102-L106 HydrophobicContact CE1-CD2 3.98Å; F102-L106 HydrophobicContact CE1-CG 4.31Å; F102-L106 HydrophobicContact CZ-CD1 4.07Å; F102-L106 VanDerWaalsContact O-CB 3.27Å; F102-L106 WeakPolarHBondContact O-CB 3.44Å; F102-L106 PolarHBondContact O-N 3Å; V103-L106 PolarHBondContact O-N 3.5Å; I104-L106 PolarHBondContact O-N 2.99Å; L106-A110 VanDerWaalsContact O-CB 3.27Å; L106-A110 WeakPolarHBondContact O-CB 3.33Å; L106-A110 PolarHBondContact O-N 3.33Å; L106-L284 HydrophobicContact CB-CD2 4.36Å; L106-L284 HydrophobicContact CD1-CD2 3.62Å; L106-F288 HydrophobicContact CD1-CE2 3.82Å; L106-F288 HydrophobicContact CD1-CZ 4.06Å; L106-F288 HydrophobicContact CG-CE2 4.48Å; L106-F321 HydrophobicContact CB-CE2 4.32Å; L106-F321 HydrophobicContact CD2-CD2 3.78Å; L106-F321 HydrophobicContact CD2-CE2 3.46Å; L106-F321 VanDerWaalsContact CD2-CE2 3.46Å; L106-F321 HydrophobicContact CD2-CZ 4.06Å; L106-F321 HydrophobicContact CG-CD2 3.81Å; L106-F321 HydrophobicContact CG-CE2 3.66Å; L106-Y324 HydrophobicContact CD1-CD2 4.34Å; L106-L325 HydrophobicContact CD2-CB 3.8Å; L106-L325 HydrophobicContact CD2-CD1 4.15Å
107	V	98.1	Very high	96.7	Very high	52 Å²	52	30.9 Å²	30.9	32%	0.315	17%	0.165	S	C	.	.	H	α-helix	trans	-63.2	-47.1	176.3	169.7	0	0	0	0	110.8	V103 I104 A110 I111 F321	V103-V107 HydrophobicContact CG1-CG2 4.49Å; V103-V107 WeakPolarHBondContact O-CB 3.46Å; V103-V107 VanDerWaalsContact O-CG2 3.28Å; V103-V107 WeakPolarHBondContact O-CG2 3.3Å; V103-V107 PolarHBondContact O-N 3.11Å; I104-V107 PolarHBondContact O-N 3.35Å; V107-A110 PolarHBondContact O-N 3.46Å; V107-I111 HydrophobicContact CG1-CD1 3.66Å; V107-I111 HydrophobicContact CG1-CG1 4.43Å; V107-I111 WeakPolarHBondContact O-CB 3.23Å; V107-I111 VanDerWaalsContact O-CG1 3.31Å; V107-I111 WeakPolarHBondContact O-CG1 3.27Å; V107-I111 PolarHBondContact O-N 3Å; V107-F321 HydrophobicContact CB-CE2 4.34Å; V107-F321 HydrophobicContact CG2-CE2 3.51Å; V107-F321 HydrophobicContact CG2-CZ 3.55Å
108	T	96.9	Very high	96.7	Very high	49 Å²	49	33.9 Å²	33.9	30%	0.301	18%	0.179	S	C	.	.	H	α-helix	trans	-60.9	-48.2	-179.5	-67.6	0	0	0	0	112	I104 L105 I111 F112	I104-T108 WeakPolarHBondContact O-CB 3.42Å; I104-T108 PolarHBondContact O-N 3.02Å; I104-T108 PolarHBondContact O-OG1 2.94Å; I104-T108 VanDerWaalsContact O-OG1 3.06Å; L105-T108 PolarHBondContact O-N 3.43Å; T108-I111 PolarHBondContact O-N 3.44Å; T108-F112 HydrophobicContact CG2-CD2 3.58Å; T108-F112 HydrophobicContact CG2-CE2 3.21Å; T108-F112 HydrophobicContact CG2-CG 4.49Å; T108-F112 HydrophobicContact CG2-CZ 3.86Å; T108-F112 WeakPolarHBondContact O-CB 3.46Å; T108-F112 WeakPolarHBondContact O-CD2 3.5Å; T108-F112 VanDerWaalsContact O-CG 3.23Å; T108-F112 WeakPolarHBondContact O-CG 3.37Å; T108-F112 PolarHBondContact O-N 3.18Å
109	V	96.9	Very high	96.7	Very high	7 Å²	7	34 Å²	34	4%	0.042	18%	0.179	C	C	.	.	H	α-helix	trans	-69	-35.5	179.7	178.9	0	0	0	0	111.7	L105 S113 L284 T285 F288	L105-V109 WeakPolarHBondContact O-CB 3.22Å; L105-V109 WeakPolarHBondContact O-CG2 3.24Å; L105-V109 PolarHBondContact O-N 3.44Å; V109-S113 VanDerWaalsContact O-CB 3.31Å; V109-S113 WeakPolarHBondContact O-CB 3.31Å; V109-S113 PolarHBondContact O-N 2.86Å; V109-S113 PolarHBondContact O-OG 3.49Å; V109-L284 HydrophobicContact CB-CB 4.46Å; V109-L284 HydrophobicContact CG1-CB 4.48Å; V109-L284 HydrophobicContact CG2-CB 4.18Å; V109-T285 HydrophobicContact CG1-CG2 4.19Å; V109-T285 HydrophobicContact CG2-CG2 4.48Å; V109-F288 HydrophobicContact CB-CD2 4.24Å; V109-F288 HydrophobicContact CG1-CB 4.21Å; V109-F288 HydrophobicContact CG1-CD2 3.73Å; V109-F288 HydrophobicContact CG1-CG 4.4Å
110	A	96.9	Very high	96.7	Very high	8 Å²	8	32.7 Å²	32.7	7%	0.066	17%	0.173	C	C	.	.	H	α-helix	trans	-63.8	-46.3	174.4	0	0	0	0	0	112.2	L106 V107 S113 L114 F288 F321	L106-A110 VanDerWaalsContact O-CB 3.27Å; L106-A110 WeakPolarHBondContact O-CB 3.33Å; L106-A110 PolarHBondContact O-N 3.33Å; V107-A110 PolarHBondContact O-N 3.46Å; A110-S113 PolarHBondContact O-N 2.86Å; A110-L114 PolarHBondContact O-N 3.17Å; A110-F288 HydrophobicContact CB-CE1 4.18Å; A110-F288 HydrophobicContact CB-CE2 4.09Å; A110-F288 HydrophobicContact CB-CZ 3.79Å; A110-F321 HydrophobicContact CB-CD2 4.16Å
111	I	97.1	Very high	96.6	Very high	101 Å²	101	31.5 Å²	31.5	52%	0.518	16%	0.163	S	C	.	.	H	α-helix	trans	-62.3	-45.6	176.6	-70.1	170.4	0	0	0	110.9	V107 T108 S113 L114 Y115	V107-I111 HydrophobicContact CG1-CD1 3.66Å; V107-I111 HydrophobicContact CG1-CG1 4.43Å; V107-I111 WeakPolarHBondContact O-CB 3.23Å; V107-I111 VanDerWaalsContact O-CG1 3.31Å; V107-I111 WeakPolarHBondContact O-CG1 3.27Å; V107-I111 PolarHBondContact O-N 3Å; T108-I111 PolarHBondContact O-N 3.44Å; I111-S113 PolarHBondContact O-N 3.47Å; I111-L114 PolarHBondContact O-N 2.82Å; I111-Y115 WeakPolarHBondContact O-CB 3.3Å; I111-Y115 PolarHBondContact O-N 3.31Å
112	F	97.1	Very high	96.5	Very high	54 Å²	54	31.1 Å²	31.1	24%	0.237	16%	0.16	C	C	.	.	H	α-helix	trans	-63.9	-38.2	177.9	-73	-22.5	0	0	0	112.9	T108 Y115 S116 F436 F463 F466	T108-F112 HydrophobicContact CG2-CD2 3.58Å; T108-F112 HydrophobicContact CG2-CE2 3.21Å; T108-F112 HydrophobicContact CG2-CG 4.49Å; T108-F112 HydrophobicContact CG2-CZ 3.86Å; T108-F112 WeakPolarHBondContact O-CB 3.46Å; T108-F112 WeakPolarHBondContact O-CD2 3.5Å; T108-F112 VanDerWaalsContact O-CG 3.23Å; T108-F112 WeakPolarHBondContact O-CG 3.37Å; T108-F112 PolarHBondContact O-N 3.18Å; F112-Y115 PolarHBondContact O-N 3Å; F112-S116 WeakPolarHBondContact O-CB 3.49Å; F112-S116 PolarHBondContact O-N 3.21Å; F112-F436 HydrophobicContact CB-CE1 4Å; F112-F436 HydrophobicContact CB-CZ 4.31Å; F112-F436 AromaticContact CD2-CE1 3.59Å; F112-F436 HydrophobicContact CD2-CE1 3.59Å; F112-F436 HydrophobicContact CD2-CZ 4.08Å; F112-F436 HydrophobicContact CE2-CE1 4.28Å; F112-F436 HydrophobicContact CG-CE1 4.04Å; F112-F463 HydrophobicContact CB-CE2 3.63Å; F112-F463 HydrophobicContact CB-CZ 3.87Å; F112-F463 HydrophobicContact CD1-CD2 4.25Å; F112-F463 AromaticContact CD1-CE2 3.68Å; F112-F463 HydrophobicContact CD1-CE2 3.68Å; F112-F463 HydrophobicContact CD2-CE2 4.25Å; F112-F463 HydrophobicContact CE1-CE2 4.37Å; F112-F463 AromaticContact CG-CE2 3.61Å; F112-F463 HydrophobicContact CG-CE2 3.61Å; F112-F463 HydrophobicContact CG-CZ 4.35Å; F112-F463 WeakPolarHBondContact O-CZ 3.41Å; F112-F466 HydrophobicContact CD2-CE1 4.02Å; F112-F466 HydrophobicContact CE2-CD1 4.07Å; F112-F466 AromaticContact CE2-CE1 3.41Å; F112-F466 HydrophobicContact CE2-CE1 3.41Å; F112-F466 VanDerWaalsContact CE2-CE1 3.41Å; F112-F466 AromaticContact CE2-CZ 3.87Å; F112-F466 HydrophobicContact CE2-CZ 3.87Å; F112-F466 HydrophobicContact CZ-CE1 4.18Å
113	S	96.9	Very high	96.3	Very high	0 Å²	0	31.1 Å²	31.1	0%	0	16%	0.16	C	C	.	.	H	α-helix	trans	-67.6	-40.9	175.6	-57.5	0	0	0	0	111.9	V109 A110 I111 S116 V117	V109-S113 VanDerWaalsContact O-CB 3.31Å; V109-S113 WeakPolarHBondContact O-CB 3.31Å; V109-S113 PolarHBondContact O-N 2.86Å; V109-S113 PolarHBondContact O-OG 3.49Å; A110-S113 PolarHBondContact O-N 2.86Å; I111-S113 PolarHBondContact O-N 3.47Å; S113-S116 PolarHBondContact O-N 3.14Å; S113-V117 WeakPolarHBondContact O-CG2 3.36Å; S113-V117 PolarHBondContact O-N 3.01Å
114	L	96.3	Very high	96	Very high	42 Å²	42	28.8 Å²	28.8	22%	0.22	15%	0.146	C	C	.	.	H	α-helix	trans	-65.1	-39.6	173.7	-82.5	172.3	0	0	0	113.4	A110 I111 H118 A313 F317	A110-L114 PolarHBondContact O-N 3.17Å; I111-L114 PolarHBondContact O-N 2.82Å; L114-H118 PolarHBondContact O-N 3.28Å; L114-H118 VanDerWaalsContact O-N 3.11Å; L114-A313 HydrophobicContact CD2-CB 4.21Å; L114-F317 HydrophobicContact CD1-CB 3.87Å; L114-F317 HydrophobicContact CD1-CG 4.32Å; L114-F317 HydrophobicContact CD2-CB 3.82Å; L114-F317 HydrophobicContact CD2-CD2 3.44Å; L114-F317 VanDerWaalsContact CD2-CD2 3.44Å; L114-F317 HydrophobicContact CD2-CE2 4.16Å; L114-F317 HydrophobicContact CD2-CG 3.73Å; L114-F317 HydrophobicContact CG-CB 3.82Å; L114-F317 HydrophobicContact CG-CD1 4.24Å; L114-F317 HydrophobicContact CG-CD2 3.9Å; L114-F317 HydrophobicContact CG-CG 3.73Å
115	Y	96.6	Very high	95.7	Very high	72 Å²	72	27.1 Å²	27.1	28%	0.282	14%	0.138	S	C	.	.	H	α-helix	trans	-64.6	-41	173.6	176.6	-116.1	0	0	0	111.5	I111 F112 H118 L119 A460 F463	I111-Y115 WeakPolarHBondContact O-CB 3.3Å; I111-Y115 PolarHBondContact O-N 3.31Å; F112-Y115 PolarHBondContact O-N 3Å; Y115-H118 VanDerWaalsContact O-CB 3.28Å; Y115-H118 WeakPolarHBondContact O-CB 3.17Å; Y115-H118 PolarHBondContact O-N 3.2Å; Y115-H118 VanDerWaalsContact O-N 3.14Å; Y115-L119 HydrophobicContact CD1-CD1 4.3Å; Y115-L119 HydrophobicContact CE1-CD1 3.74Å; Y115-L119 HydrophobicContact CE1-CG 4.23Å; Y115-L119 HydrophobicContact CE2-CD2 4.12Å; Y115-L119 HydrophobicContact CE2-CG 4.33Å; Y115-L119 PolarHBondContact O-N 2.9Å; Y115-A460 PolarHBondContact OH-N 3.29Å; Y115-F463 AromaticContact CD1-CD1 3.72Å; Y115-F463 HydrophobicContact CD1-CD1 3.72Å; Y115-F463 HydrophobicContact CD1-CD2 4.39Å; Y115-F463 AromaticContact CD1-CE1 3.86Å; Y115-F463 HydrophobicContact CD1-CE1 3.86Å; Y115-F463 HydrophobicContact CD1-CE2 4.48Å; Y115-F463 HydrophobicContact CD1-CG 4.04Å; Y115-F463 HydrophobicContact CD1-CZ 4.25Å; Y115-F463 HydrophobicContact CE1-CB 4.11Å; Y115-F463 AromaticContact CE1-CD1 3.71Å; Y115-F463 HydrophobicContact CE1-CD1 3.71Å; Y115-F463 HydrophobicContact CE1-CE1 4.31Å; Y115-F463 AromaticContact CE1-CG 3.91Å; Y115-F463 HydrophobicContact CE1-CG 3.91Å
116	S	97.1	Very high	95.3	Very high	0 Å²	0	29.9 Å²	29.9	0%	0	15%	0.15	C	C	.	.	H	α-helix	trans	-64	-45.5	177.1	-169.8	0	0	0	0	113.1	F112 S113 H118 L119 L120 H291 I435 P439	F112-S116 WeakPolarHBondContact O-CB 3.49Å; F112-S116 PolarHBondContact O-N 3.21Å; S113-S116 PolarHBondContact O-N 3.14Å; S116-H118 PolarHBondContact O-N 3.19Å; S116-L119 PolarHBondContact O-N 2.7Å; S116-L119 VanDerWaalsContact O-N 3.11Å; S116-L120 WeakPolarHBondContact O-CB 3.31Å; S116-L120 PolarHBondContact O-N 3.33Å; S116-H291 WeakPolarHBondContact CB-NE2 3.31Å; S116-H291 PolarHBondContact OG-NE2 2.71Å; S116-I435 WeakPolarHBondContact CB-O 3.38Å; S116-I435 PolarHBondContact OG-O 3.2Å; S116-P439 WeakPolarHBondContact OG-CB 3.44Å; S116-P439 VanDerWaalsContact OG-CG 3.23Å; S116-P439 WeakPolarHBondContact OG-CG 3.5Å
117	V	96.5	Very high	94.9	Very high	0 Å²	0	30.9 Å²	30.9	0%	0	16%	0.158	C	C	.	.	H	α-helix	trans	-52.7	-41.6	169.7	159.4	0	0	0	0	111.5	S113 L120 L121 I294 A313 F317	S113-V117 WeakPolarHBondContact O-CG2 3.36Å; S113-V117 PolarHBondContact O-N 3.01Å; V117-L120 PolarHBondContact O-N 2.7Å; V117-L121 HydrophobicContact CG1-CD1 3.84Å; V117-L121 HydrophobicContact CG1-CG 4.39Å; V117-L121 WeakPolarHBondContact O-CB 3.26Å; V117-L121 WeakPolarHBondContact O-CG 3.17Å; V117-L121 PolarHBondContact O-N 3.48Å; V117-I294 HydrophobicContact CB-CD1 4.05Å; V117-I294 HydrophobicContact CG1-CD1 3.39Å; V117-I294 HydrophobicContact CG2-CD1 3.51Å; V117-A313 HydrophobicContact CG1-CB 3.8Å; V117-F317 HydrophobicContact CG2-CE2 4.2Å
118	H	95.4	Very high	94.4	Very high	62 Å²	62	31.1 Å²	31.1	29%	0.287	17%	0.171	S	C	.	.	H	α-helix	trans	-63.1	-45.8	176.9	-171.8	75.2	0	0	0	112.7	L114 Y115 S116 K122 Q310	L114-H118 PolarHBondContact O-N 3.28Å; L114-H118 VanDerWaalsContact O-N 3.11Å; Y115-H118 VanDerWaalsContact O-CB 3.28Å; Y115-H118 WeakPolarHBondContact O-CB 3.17Å; Y115-H118 PolarHBondContact O-N 3.2Å; Y115-H118 VanDerWaalsContact O-N 3.14Å; S116-H118 PolarHBondContact O-N 3.19Å; H118-K122 WeakPolarHBondContact O-CB 3.23Å; H118-K122 PolarHBondContact O-N 3.45Å; H118-K122 VanDerWaalsContact O-N 3.09Å; H118-Q310 PolarHBondContact ND1-OE1 2.56Å
119	L	94.9	Very high	94	Very high	2 Å²	2	29.5 Å²	29.5	1%	0.01	16%	0.163	C	C	.	.	H	α-helix	trans	-60.8	-45.7	175.2	-63.6	-177.1	0	0	0	111.1	Y115 S116 K122 T123 P439 Y443 A460 F463	Y115-L119 HydrophobicContact CD1-CD1 4.3Å; Y115-L119 HydrophobicContact CE1-CD1 3.74Å; Y115-L119 HydrophobicContact CE1-CG 4.23Å; Y115-L119 HydrophobicContact CE2-CD2 4.12Å; Y115-L119 HydrophobicContact CE2-CG 4.33Å; Y115-L119 PolarHBondContact O-N 2.9Å; S116-L119 PolarHBondContact O-N 2.7Å; S116-L119 VanDerWaalsContact O-N 3.11Å; L119-K122 PolarHBondContact O-N 2.96Å; L119-T123 PolarHBondContact O-N 2.94Å; L119-T123 PolarHBondContact O-OG1 3.2Å; L119-P439 HydrophobicContact CB-CB 4.41Å; L119-Y443 HydrophobicContact CB-CD2 4.32Å; L119-Y443 HydrophobicContact CB-CG 4.5Å; L119-Y443 HydrophobicContact CD2-CD1 4.13Å; L119-Y443 HydrophobicContact CD2-CD2 3.72Å; L119-Y443 HydrophobicContact CD2-CE1 4.41Å; L119-Y443 HydrophobicContact CD2-CE2 4.03Å; L119-Y443 HydrophobicContact CD2-CG 3.79Å; L119-A460 HydrophobicContact CD1-CB 4.15Å; L119-F463 HydrophobicContact CD1-CD1 4.25Å
120	L	95	Very high	93.4	Very high	0 Å²	0	30.2 Å²	30.2	0%	0	17%	0.166	C	C	.	.	H	α-helix	trans	-64.3	-48.4	-177.3	-171.6	63.2	0	0	0	111.9	S116 V117 K122 T123 A124 Y132 L135 I294 L295 P439 L442	S116-L120 WeakPolarHBondContact O-CB 3.31Å; S116-L120 PolarHBondContact O-N 3.33Å; V117-L120 PolarHBondContact O-N 2.7Å; L120-K122 VanDerWaalsContact C-N 3.32Å; L120-K122 PolarHBondContact O-N 2.86Å; L120-T123 WeakPolarHBondContact CA-OG1 3.26Å; L120-T123 PolarHBondContact O-N 3.45Å; L120-T123 PolarHBondContact O-OG1 3.44Å; L120-A124 WeakPolarHBondContact O-CB 3.28Å; L120-A124 PolarHBondContact O-N 2.93Å; L120-Y132 HydrophobicContact CD1-CD2 4.23Å; L120-Y132 HydrophobicContact CD1-CE2 3.83Å; L120-Y132 HydrophobicContact CD2-CD2 4.03Å; L120-Y132 HydrophobicContact CD2-CE2 3.57Å; L120-Y132 HydrophobicContact CG-CE2 4.38Å; L120-L135 HydrophobicContact CD1-CD2 4.11Å; L120-I294 HydrophobicContact CD2-CG2 3.87Å; L120-L295 HydrophobicContact CD1-CD1 4.16Å; L120-L295 HydrophobicContact CD2-CD1 4.31Å; L120-L295 HydrophobicContact CD2-CG 4.19Å; L120-L295 HydrophobicContact CG-CD1 4.16Å; L120-L295 HydrophobicContact CG-CD2 4.19Å; L120-L295 HydrophobicContact CG-CG 4.26Å; L120-P439 HydrophobicContact CB-CB 4.29Å; L120-P439 HydrophobicContact CD1-CG 4.47Å; L120-L442 HydrophobicContact CD1-CD1 4.18Å
121	L	94.2	Very high	92.9	Very high	0 Å²	0	31.8 Å²	31.8	0%	0	18%	0.175	C	C	.	.	H	α-helix	trans	-62.3	-38.6	176	-68.9	171.6	0	0	0	111.8	V117 A124 D125 L295 Y298 R306 M309	V117-L121 HydrophobicContact CG1-CD1 3.84Å; V117-L121 HydrophobicContact CG1-CG 4.39Å; V117-L121 WeakPolarHBondContact O-CB 3.26Å; V117-L121 WeakPolarHBondContact O-CG 3.17Å; V117-L121 PolarHBondContact O-N 3.48Å; L121-A124 PolarHBondContact O-N 3.34Å; L121-D125 PolarHBondContact O-N 3.1Å; L121-D125 VanDerWaalsContact O-N 3.09Å; L121-L295 HydrophobicContact CD2-CD2 4.28Å; L121-Y298 HydrophobicContact CD2-CD1 3.66Å; L121-Y298 HydrophobicContact CD2-CE1 4.18Å; L121-Y298 HydrophobicContact CD2-CG 3.89Å; L121-R306 HydrophobicContact CB-CG 4.05Å; L121-M309 HydrophobicContact CD1-CB 4.08Å; L121-M309 HydrophobicContact CD1-CG 3.97Å; L121-M309 HydrophobicContact CD2-CB 4.34Å; L121-M309 HydrophobicContact CD2-CG 3.84Å
122	K	93	Very high	92.5	Very high	23 Å²	23	27.2 Å²	27.2	10%	0.1	15%	0.151	C	C	.	.	H	α-helix	trans	-68.6	-34.2	176	-174.5	168.1	168.2	-164	0	112.5	H118 L119 L120 E126 Y443 E450	H118-K122 WeakPolarHBondContact O-CB 3.23Å; H118-K122 PolarHBondContact O-N 3.45Å; H118-K122 VanDerWaalsContact O-N 3.09Å; L119-K122 PolarHBondContact O-N 2.96Å; L120-K122 VanDerWaalsContact C-N 3.32Å; L120-K122 PolarHBondContact O-N 2.86Å; K122-E126 WeakPolarHBondContact O-CG 3.41Å; K122-E126 PolarHBondContact O-N 3.43Å; K122-Y443 HydrophobicContact CD-CE2 3.79Å; K122-Y443 HydrophobicContact CG-CE2 4.13Å; K122-Y443 PolarHBondContact NZ-OH 2.93Å; K122-E450 IonicContact NZ-OE1 3.87Å; K122-E450 PolarHBondContact NZ-OE1 2.93Å
123	T	93.2	Very high	92.2	Very high	0 Å²	0	25 Å²	25	0%	0	14%	0.142	C	C	.	.	H	α-helix	trans	-69.5	-36.2	170.6	48.5	0	0	0	0	113.3	L119 L120 A127 L135 L442 Y443 L446 V447	L119-T123 PolarHBondContact O-N 2.94Å; L119-T123 PolarHBondContact O-OG1 3.2Å; L120-T123 WeakPolarHBondContact CA-OG1 3.26Å; L120-T123 PolarHBondContact O-N 3.45Å; L120-T123 PolarHBondContact O-OG1 3.44Å; T123-A127 WeakPolarHBondContact O-CB 3.32Å; T123-A127 PolarHBondContact O-N 2.71Å; T123-L135 WeakPolarHBondContact OG1-CD2 3.44Å; T123-L442 HydrophobicContact CG2-CB 4.15Å; T123-Y443 HydrophobicContact CG2-CD2 4.16Å; T123-L446 HydrophobicContact CG2-CB 4.5Å; T123-L446 HydrophobicContact CG2-CD1 4.47Å; T123-V447 HydrophobicContact CG2-CG2 4.01Å
124	A	92.3	Very high	91.9	Very high	2 Å²	2	26.8 Å²	26.8	2%	0.017	15%	0.154	C	C	.	.	H	α-helix	trans	-66.2	-43	179.9	0	0	0	0	0	111.8	L120 L121 G128 A129 L130 L135 L295	L120-A124 WeakPolarHBondContact O-CB 3.28Å; L120-A124 PolarHBondContact O-N 2.93Å; L121-A124 PolarHBondContact O-N 3.34Å; A124-G128 PolarHBondContact O-N 3.25Å; A124-G128 VanDerWaalsContact O-N 3.1Å; A124-A129 PolarHBondContact O-N 3.21Å; A124-L130 HydrophobicContact CB-CD2 4.1Å; A124-L135 HydrophobicContact CB-CD2 4.36Å; A124-L295 HydrophobicContact CB-CD2 3.69Å
125	D	90.4	Very high	91.7	Very high	60 Å²	60	24.8 Å²	24.8	32%	0.321	14%	0.144	S	C	.	.	H	α-helix	trans	-58.5	-56.8	171.2	-76.1	-12	0	0	0	111.7	L121 A127 G128 Y298 R306	L121-D125 PolarHBondContact O-N 3.1Å; L121-D125 VanDerWaalsContact O-N 3.09Å; D125-A127 PolarHBondContact O-N 3.41Å; D125-G128 PolarHBondContact O-N 2.89Å; D125-Y298 WeakPolarHBondContact OD1-CE1 3.23Å; D125-Y298 PolarHBondContact OD1-OH 3.47Å; D125-R306 WeakPolarHBondContact OD2-CB 3.27Å; D125-R306 WeakPolarHBondContact OD2-CD 3.27Å; D125-R306 IonicContact OD2-CZ 3.29Å; D125-R306 IonicContact OD2-NE 3.53Å; D125-R306 IonicContact OD2-NH1 2.71Å; D125-R306 PolarHBondContact OD2-NH1 3.07Å
126	E	89.6	Confident	91.5	Very high	94 Å²	94	21.4 Å²	21.4	44%	0.439	13%	0.131	S	C	.	.	H	α-helix	trans	-71	-29.5	-173.2	-67.6	-89.8	158.4	0	0	113.1	K122 V447	K122-E126 WeakPolarHBondContact O-CG 3.41Å; K122-E126 PolarHBondContact O-N 3.43Å; E126-V447 HydrophobicContact CG-CG2 4.47Å
127	A	88.9	Confident	91.3	Very high	20 Å²	20	25.9 Å²	25.9	17%	0.165	15%	0.152	C	C	.	.	H	α-helix	trans	-89.9	-9.9	178.2	0	0	0	0	0	113.9	T123 D125 L135 K138 L446	T123-A127 WeakPolarHBondContact O-CB 3.32Å; T123-A127 PolarHBondContact O-N 2.71Å; D125-A127 PolarHBondContact O-N 3.41Å; A127-L135 HydrophobicContact CB-CD1 4.33Å; A127-K138 HydrophobicContact CB-CD 4.39Å; A127-K138 PolarHBondContact O-NZ 3.29Å; A127-L446 HydrophobicContact CB-CD1 3.99Å; A127-L446 HydrophobicContact CB-CD2 4.28Å
128	G	87.2	Confident	91.1	Very high	57 Å²	57	31.2 Å²	31.2	59%	0.588	18%	0.175	S	C	*	.	T	Hydrogen-bonded Turn	trans	57.8	54.3	-178.2	0	0	0	0	0	112.8	A124 D125 K138	A124-G128 PolarHBondContact O-N 3.25Å; A124-G128 VanDerWaalsContact O-N 3.1Å; D125-G128 PolarHBondContact O-N 2.89Å; G128-K138 PolarHBondContact O-NZ 2.87Å
129	A	87.6	Confident	91	Very high	16 Å²	16	28.7 Å²	28.7	13%	0.132	17%	0.165	C	C	.	.			trans	-156.3	140.8	172.7	0	0	0	0	0	111.1	A124 L135 K138	A124-A129 PolarHBondContact O-N 3.21Å; A129-L135 HydrophobicContact CB-CD1 3.61Å; A129-L135 WeakPolarHBondContact O-CD1 3.14Å; A129-K138 HydrophobicContact CB-CD 4.25Å
130	L	84.9	Confident	91	Very high	21 Å²	21	32.8 Å²	32.8	11%	0.11	18%	0.183	C	C	.	.			trans	-114.9	11.7	-175.8	-59.2	177.3	0	0	0	112.8	A124 L295 Y298 E299 R304	A124-L130 HydrophobicContact CB-CD2 4.1Å; L130-L295 VanDerWaalsContact O-CB 3.24Å; L130-L295 WeakPolarHBondContact O-CB 3.5Å; L130-Y298 HydrophobicContact CD2-CD1 3.65Å; L130-Y298 HydrophobicContact CD2-CE1 4Å; L130-E299 HydrophobicContact CB-CB 4.38Å; L130-E299 HydrophobicContact CD1-CB 3.86Å; L130-E299 HydrophobicContact CD1-CG 4.14Å; L130-E299 WeakPolarHBondContact CD1-OE1 3.24Å; L130-R304 VanDerWaalsContact CD1-CZ 3.44Å
131	V	87.3	Confident	90.9	Very high	41 Å²	41	34 Å²	34	25%	0.248	20%	0.195	C	C	.	.			trans	-110.6	128	171	176.5	0	0	0	0	108.6	E133 S134 L135	V131-E133 HydrophobicContact CG1-CB 4.38Å; V131-E133 VanDerWaalsContact CG1-OE2 3.28Å; V131-E133 WeakPolarHBondContact CG1-OE2 3.47Å; V131-E133 PolarHBondContact O-N 3.47Å; V131-S134 WeakPolarHBondContact O-CB 3.33Å; V131-S134 PolarHBondContact O-N 2.88Å; V131-S134 VanDerWaalsContact O-N 3.1Å; V131-L135 PolarHBondContact O-N 3.41Å; V131-L135 VanDerWaalsContact O-N 3.09Å
132	Y	88.9	Confident	90.8	Very high	5 Å²	5	40.2 Å²	40.2	2%	0.02	23%	0.227	C	C	.	.	H	α-helix	trans	-64.4	-42	-171.4	-157.3	-57.4	0	0	0	111.6	L120 S134 L135 G136 A148 I152 H291 L295 L434 L438 P439 L442	L120-Y132 HydrophobicContact CD1-CD2 4.23Å; L120-Y132 HydrophobicContact CD1-CE2 3.83Å; L120-Y132 HydrophobicContact CD2-CD2 4.03Å; L120-Y132 HydrophobicContact CD2-CE2 3.57Å; L120-Y132 HydrophobicContact CG-CE2 4.38Å; Y132-S134 PolarHBondContact O-N 3.47Å; Y132-L135 WeakPolarHBondContact O-CA 3.42Å; Y132-L135 VanDerWaalsContact O-CB 3.3Å; Y132-L135 WeakPolarHBondContact O-CB 3.3Å; Y132-L135 PolarHBondContact O-N 2.86Å; Y132-L135 VanDerWaalsContact O-N 3.09Å; Y132-G136 PolarHBondContact O-N 2.62Å; Y132-A148 HydrophobicContact CD1-CB 3.76Å; Y132-A148 HydrophobicContact CE1-CB 4.2Å; Y132-I152 HydrophobicContact CD1-CD1 4.26Å; Y132-I152 HydrophobicContact CD2-CD1 4.32Å; Y132-I152 HydrophobicContact CG-CD1 3.86Å; Y132-H291 HydrophobicContact CE2-CB 4.31Å; Y132-L295 HydrophobicContact CD2-CD1 4.16Å; Y132-L295 HydrophobicContact CG-CD1 4.39Å; Y132-L434 HydrophobicContact CE1-CD2 4.45Å; Y132-L434 HydrophobicContact CE2-CD2 4.17Å; Y132-L434 PolarHBondContact OH-O 2.89Å; Y132-L438 HydrophobicContact CE1-CB 4.03Å; Y132-L438 HydrophobicContact CE1-CD1 4.02Å; Y132-L438 WeakPolarHBondContact OH-CB 3.21Å; Y132-P439 WeakPolarHBondContact OH-CD 3.15Å; Y132-P439 WeakPolarHBondContact OH-CG 3.22Å; Y132-L442 HydrophobicContact CE1-CD1 3.97Å
133	E	90.4	Very high	90.8	Very high	8 Å²	8	43.5 Å²	43.5	4%	0.037	25%	0.251	C	S	.	.	H	α-helix	trans	-62	-33.2	175.5	-62.7	86.1	163.7	0	0	111.9	V131 G136 H137 K145 A148 S382	V131-E133 HydrophobicContact CG1-CB 4.38Å; V131-E133 VanDerWaalsContact CG1-OE2 3.28Å; V131-E133 WeakPolarHBondContact CG1-OE2 3.47Å; V131-E133 PolarHBondContact O-N 3.47Å; E133-G136 PolarHBondContact O-N 3.39Å; E133-H137 WeakPolarHBondContact O-CB 3.1Å; E133-H137 PolarHBondContact O-N 3.21Å; E133-K145 HydrophobicContact CB-CG 4.2Å; E133-A148 HydrophobicContact CG-CB 4.38Å; E133-S382 VanDerWaalsContact OE1-CA 3.26Å; E133-S382 WeakPolarHBondContact OE1-CA 3.27Å; E133-S382 VanDerWaalsContact OE1-CB 3.23Å; E133-S382 WeakPolarHBondContact OE1-CB 3.45Å; E133-S382 PolarHBondContact OE1-OG 3.47Å
134	S	89.6	Confident	90.8	Very high	38 Å²	38	43.8 Å²	43.8	27%	0.266	25%	0.254	S	S	.	.	H	α-helix	trans	-72.7	-32.2	174.7	-66.6	0	0	0	0	112.1	V131 Y132 H137 K138	V131-S134 WeakPolarHBondContact O-CB 3.33Å; V131-S134 PolarHBondContact O-N 2.88Å; V131-S134 VanDerWaalsContact O-N 3.1Å; Y132-S134 PolarHBondContact O-N 3.47Å; S134-H137 PolarHBondContact O-N 2.97Å; S134-K138 WeakPolarHBondContact O-CB 3.43Å; S134-K138 WeakPolarHBondContact O-CG 3.37Å; S134-K138 PolarHBondContact O-N 3.21Å
135	L	92.1	Very high	90.8	Very high	0 Å²	0	46 Å²	46	0%	0	26%	0.263	C	S	.	.	H	α-helix	trans	-64.4	-47.8	167.4	-106.9	61.9	0	0	0	111.1	L120 T123 A124 A127 A129 V131 Y132 H137 K138 A139 L295 L442 L446	L120-L135 HydrophobicContact CD1-CD2 4.11Å; T123-L135 WeakPolarHBondContact OG1-CD2 3.44Å; A124-L135 HydrophobicContact CB-CD2 4.36Å; A127-L135 HydrophobicContact CB-CD1 4.33Å; A129-L135 HydrophobicContact CB-CD1 3.61Å; A129-L135 WeakPolarHBondContact O-CD1 3.14Å; V131-L135 PolarHBondContact O-N 3.41Å; V131-L135 VanDerWaalsContact O-N 3.09Å; Y132-L135 WeakPolarHBondContact O-CA 3.42Å; Y132-L135 VanDerWaalsContact O-CB 3.3Å; Y132-L135 WeakPolarHBondContact O-CB 3.3Å; Y132-L135 PolarHBondContact O-N 2.86Å; Y132-L135 VanDerWaalsContact O-N 3.09Å; L135-H137 VanDerWaalsContact C-N 3.26Å; L135-H137 PolarHBondContact O-N 3.28Å; L135-K138 PolarHBondContact O-N 3.48Å; L135-A139 WeakPolarHBondContact O-CB 3.47Å; L135-A139 PolarHBondContact O-N 2.91Å; L135-L295 HydrophobicContact CD2-CD1 4.37Å; L135-L442 HydrophobicContact CB-CD1 4.2Å; L135-L442 HydrophobicContact CB-CD2 4.12Å; L135-L442 HydrophobicContact CD2-CD1 4.36Å; L135-L442 WeakPolarHBondContact O-CD2 3.46Å; L135-L446 HydrophobicContact CG-CD1 4.14Å
136	G	93.2	Very high	90.8	Very high	1 Å²	1	47 Å²	47	1%	0.01	27%	0.268	C	S	.	.	H	α-helix	trans	-53.7	-44	173	0	0	0	0	0	112.3	Y132 E133 A139 F140 G144	Y132-G136 PolarHBondContact O-N 2.62Å; E133-G136 PolarHBondContact O-N 3.39Å; G136-A139 PolarHBondContact O-N 3.5Å; G136-F140 PolarHBondContact O-N 3.36Å; G136-G144 WeakPolarHBondContact O-CA 3.4Å
137	H	92.8	Very high	91.1	Very high	94 Å²	94	44.3 Å²	44.3	44%	0.435	26%	0.262	S	S	.	.	H	α-helix	trans	-67.3	-46	177.3	-159.8	59.3	0	0	0	113.2	E133 S134 L135 A139 G141 K145	E133-H137 WeakPolarHBondContact O-CB 3.1Å; E133-H137 PolarHBondContact O-N 3.21Å; S134-H137 PolarHBondContact O-N 2.97Å; L135-H137 VanDerWaalsContact C-N 3.26Å; L135-H137 PolarHBondContact O-N 3.28Å; H137-A139 VanDerWaalsContact C-N 3.25Å; H137-A139 PolarHBondContact O-N 2.91Å; H137-G141 WeakPolarHBondContact CA-O 3.38Å; H137-G141 VanDerWaalsContact ND1-C 3.25Å; H137-G141 PolarHBondContact ND1-O 3.13Å; H137-G141 VanDerWaalsContact O-CA 3.23Å; H137-G141 WeakPolarHBondContact O-CA 3.41Å; H137-G141 PolarHBondContact O-N 3.4Å; H137-K145 HydrophobicContact CB-CB 4.03Å; H137-K145 HydrophobicContact CB-CG 4.43Å
138	K	92.6	Very high	91.2	Very high	111 Å²	111	43.3 Å²	43.3	48%	0.483	25%	0.254	S	S	.	.	H	α-helix	trans	-63.1	-29.3	177.1	-76.5	177.4	173.3	-174.3	0	113	A127 G128 A129 S134 L135 L446	A127-K138 HydrophobicContact CB-CD 4.39Å; A127-K138 PolarHBondContact O-NZ 3.29Å; G128-K138 PolarHBondContact O-NZ 2.87Å; A129-K138 HydrophobicContact CB-CD 4.25Å; S134-K138 WeakPolarHBondContact O-CB 3.43Å; S134-K138 WeakPolarHBondContact O-CG 3.37Å; S134-K138 PolarHBondContact O-N 3.21Å; L135-K138 PolarHBondContact O-N 3.48Å; K138-L446 HydrophobicContact CB-CD2 4.1Å
139	A	93.5	Very high	91.4	Very high	9 Å²	9	40.7 Å²	40.7	7%	0.074	23%	0.226	C	C	.	.	H	α-helix	trans	-86.3	-48.3	-178.5	0	0	0	0	0	113.8	L135 G136 H137 L442 K445 L446	L135-A139 WeakPolarHBondContact O-CB 3.47Å; L135-A139 PolarHBondContact O-N 2.91Å; G136-A139 PolarHBondContact O-N 3.5Å; H137-A139 VanDerWaalsContact C-N 3.25Å; H137-A139 PolarHBondContact O-N 2.91Å; A139-L442 HydrophobicContact CB-CD2 3.55Å; A139-K445 HydrophobicContact CB-CB 4.33Å; A139-K445 HydrophobicContact CB-CG 4Å; A139-K445 WeakPolarHBondContact O-CE 3.1Å; A139-K445 VanDerWaalsContact O-CG 3.3Å; A139-K445 WeakPolarHBondContact O-CG 3.1Å; A139-L446 HydrophobicContact CB-CD1 4.06Å; A139-L446 HydrophobicContact CB-CD2 4Å; A139-L446 HydrophobicContact CB-CG 3.87Å
140	F	94.3	Very high	91.7	Very high	89 Å²	89	42.8 Å²	42.8	39%	0.39	24%	0.239	S	C	.	.	H	α-helix	trans	-133.6	11.9	-169.9	-55	-81.3	0	0	0	113.8	G136 P143 A441 K445	G136-F140 PolarHBondContact O-N 3.36Å; F140-P143 WeakPolarHBondContact O-CD 3.25Å; F140-P143 WeakPolarHBondContact O-CG 3.31Å; F140-A441 HydrophobicContact CE2-CB 3.92Å; F140-A441 HydrophobicContact CZ-CB 3.95Å; F140-A441 WeakPolarHBondContact CZ-O 3.47Å; F140-K445 HydrophobicContact CD1-CG 4.43Å; F140-K445 HydrophobicContact CE1-CB 4.24Å; F140-K445 HydrophobicContact CE1-CD 4.05Å; F140-K445 HydrophobicContact CE1-CG 3.94Å; F140-K445 HydrophobicContact CE2-CB 4.27Å; F140-K445 HydrophobicContact CE2-CG 4.39Å; F140-K445 HydrophobicContact CZ-CB 3.76Å; F140-K445 HydrophobicContact CZ-CD 4.44Å; F140-K445 HydrophobicContact CZ-CG 3.91Å
141	G	93.1	Very high	92.2	Very high	26 Å²	26	42.3 Å²	42.3	27%	0.268	24%	0.238	S	C	.	.	H	α-helix	trans	68.3	-141.5	179.2	0	0	0	0	0	113.1	H137 G144 K145	H137-G141 WeakPolarHBondContact CA-O 3.38Å; H137-G141 VanDerWaalsContact ND1-C 3.25Å; H137-G141 PolarHBondContact ND1-O 3.13Å; H137-G141 VanDerWaalsContact O-CA 3.23Å; H137-G141 WeakPolarHBondContact O-CA 3.41Å; H137-G141 PolarHBondContact O-N 3.4Å; G141-G144 PolarHBondContact O-N 2.97Å; G141-K145 PolarHBondContact O-N 3.48Å; G141-K145 VanDerWaalsContact O-N 3.08Å
142	I	91	Very high	92.4	Very high	129 Å²	129	40.5 Å²	40.5	66%	0.662	23%	0.227	S	C	*	.	H	α-helix	trans	-56.6	-49.5	-177.4	-58.8	176.2	0	0	0	113.2	G144 K145 L146	I142-G144 VanDerWaalsContact C-N 3.34Å; I142-G144 PolarHBondContact O-N 3.48Å; I142-K145 WeakPolarHBondContact O-CB 3.25Å; I142-K145 PolarHBondContact O-N 3.48Å; I142-L146 WeakPolarHBondContact O-CB 3.35Å; I142-L146 PolarHBondContact O-N 3.34Å
143	P	93.8	Very high	92.6	Very high	92 Å²	92	41.5 Å²	41.5	60%	0.597	23%	0.233	S	C	*	.	H	α-helix	trans	-65.1	-34.6	-178.5	23.9	-33.8	0	0	0	113.2	F140 L146 A147	F140-P143 WeakPolarHBondContact O-CD 3.25Å; F140-P143 WeakPolarHBondContact O-CG 3.31Å; P143-L146 PolarHBondContact O-N 3.07Å; P143-A147 VanDerWaalsContact O-CB 3.32Å; P143-A147 WeakPolarHBondContact O-CB 3.38Å; P143-A147 PolarHBondContact O-N 3Å
144	G	93.1	Very high	92.7	Very high	6 Å²	6	44.7 Å²	44.7	6%	0.062	25%	0.249	C	C	.	.	H	α-helix	trans	-67	-40.6	174.5	0	0	0	0	0	113	G136 G141 I142 A148	G136-G144 WeakPolarHBondContact O-CA 3.4Å; G141-G144 PolarHBondContact O-N 2.97Å; I142-G144 VanDerWaalsContact C-N 3.34Å; I142-G144 PolarHBondContact O-N 3.48Å; G144-A148 WeakPolarHBondContact O-CB 3.25Å; G144-A148 PolarHBondContact O-N 2.92Å; G144-A148 VanDerWaalsContact O-N 3.14Å
145	K	91.7	Very high	93	Very high	48 Å²	48	43.1 Å²	43.1	21%	0.209	24%	0.238	C	C	.	.	H	α-helix	trans	-60.5	-46.1	172.8	-174.1	-169.6	171.6	-169	0	111.2	E133 H137 G141 I142 S149 H385	E133-K145 HydrophobicContact CB-CG 4.2Å; H137-K145 HydrophobicContact CB-CB 4.03Å; H137-K145 HydrophobicContact CB-CG 4.43Å; G141-K145 PolarHBondContact O-N 3.48Å; G141-K145 VanDerWaalsContact O-N 3.08Å; I142-K145 WeakPolarHBondContact O-CB 3.25Å; I142-K145 PolarHBondContact O-N 3.48Å; K145-S149 VanDerWaalsContact O-CB 3.31Å; K145-S149 WeakPolarHBondContact O-CB 3.42Å; K145-S149 PolarHBondContact O-N 3.46Å; K145-H385 VanDerWaalsContact CE-O 3.27Å; K145-H385 WeakPolarHBondContact CE-O 3.17Å; K145-H385 PolarHBondContact NZ-O 3.43Å
146	L	92.3	Very high	93	Very high	81 Å²	81	43.5 Å²	43.5	42%	0.424	24%	0.239	S	C	.	.	H	α-helix	trans	-65.8	-46.7	-179.7	-174.5	65	0	0	0	111.5	I142 P143 A148 S149 C150 L386	I142-L146 WeakPolarHBondContact O-CB 3.35Å; I142-L146 PolarHBondContact O-N 3.34Å; P143-L146 PolarHBondContact O-N 3.07Å; L146-A148 VanDerWaalsContact C-N 3.33Å; L146-A148 PolarHBondContact O-N 3.04Å; L146-S149 PolarHBondContact O-N 3.44Å; L146-C150 WeakPolarHBondContact O-CB 3.31Å; L146-C150 PolarHBondContact O-N 2.99Å; L146-C150 PolarHBondContact O-SG 2.94Å; L146-C150 VanDerWaalsContact O-SG 3.38Å; L146-L386 HydrophobicContact CD1-CD1 3.72Å
147	A	93.9	Very high	93	Very high	38 Å²	38	45.6 Å²	45.6	31%	0.314	25%	0.25	S	S	.	.	H	α-helix	trans	-58.6	-43.4	178.1	0	0	0	0	0	112.2	P143 S151 L438	P143-A147 VanDerWaalsContact O-CB 3.32Å; P143-A147 WeakPolarHBondContact O-CB 3.38Å; P143-A147 PolarHBondContact O-N 3Å; A147-S151 VanDerWaalsContact O-CB 3.29Å; A147-S151 WeakPolarHBondContact O-CB 3.44Å; A147-S151 PolarHBondContact O-N 3.29Å; A147-S151 VanDerWaalsContact O-N 3.13Å; A147-S151 PolarHBondContact O-OG 3.04Å; A147-L438 HydrophobicContact CB-CD2 4.17Å
148	A	92.8	Very high	93.1	Very high	0 Å²	0	41.1 Å²	41.1	0%	0	23%	0.229	C	C	.	.	H	α-helix	trans	-61.6	-55.4	172.6	0	0	0	0	0	111.9	Y132 E133 G144 L146 C150 S151 I152	Y132-A148 HydrophobicContact CD1-CB 3.76Å; Y132-A148 HydrophobicContact CE1-CB 4.2Å; E133-A148 HydrophobicContact CG-CB 4.38Å; G144-A148 WeakPolarHBondContact O-CB 3.25Å; G144-A148 PolarHBondContact O-N 2.92Å; G144-A148 VanDerWaalsContact O-N 3.14Å; L146-A148 VanDerWaalsContact C-N 3.33Å; L146-A148 PolarHBondContact O-N 3.04Å; A148-C150 PolarHBondContact O-N 2.74Å; A148-S151 PolarHBondContact O-N 3.44Å; A148-I152 WeakPolarHBondContact O-CB 3.24Å; A148-I152 WeakPolarHBondContact O-CG1 3.37Å; A148-I152 PolarHBondContact O-N 3.05Å
149	S	91.6	Very high	93.1	Very high	1 Å²	1	36.4 Å²	36.4	1%	0.007	21%	0.211	C	C	.	.	H	α-helix	trans	-57.7	-45.2	-176.9	178.4	0	0	0	0	112.9	K145 L146 T153 S382	K145-S149 VanDerWaalsContact O-CB 3.31Å; K145-S149 WeakPolarHBondContact O-CB 3.42Å; K145-S149 PolarHBondContact O-N 3.46Å; L146-S149 PolarHBondContact O-N 3.44Å; S149-T153 VanDerWaalsContact O-CB 3.27Å; S149-T153 WeakPolarHBondContact O-CB 3.39Å; S149-T153 PolarHBondContact O-N 2.86Å; S149-T153 PolarHBondContact O-OG1 3.28Å; S149-S382 PolarHBondContact OG-O 2.93Å
150	C	92.8	Very high	93.1	Very high	61 Å²	61	36 Å²	36	41%	0.412	21%	0.208	S	C	.	.	H	α-helix	trans	-67.6	-40.3	178.3	-68.5	0	0	0	0	111.9	L146 A148 T153 M154	L146-C150 WeakPolarHBondContact O-CB 3.31Å; L146-C150 PolarHBondContact O-N 2.99Å; L146-C150 PolarHBondContact O-SG 2.94Å; L146-C150 VanDerWaalsContact O-SG 3.38Å; A148-C150 PolarHBondContact O-N 2.74Å; C150-T153 PolarHBondContact O-N 3.46Å; C150-M154 VanDerWaalsContact O-CB 3.23Å; C150-M154 WeakPolarHBondContact O-CB 3.42Å; C150-M154 PolarHBondContact O-N 3.44Å
151	S	94.7	Very high	93.2	Very high	10 Å²	10	32.2 Å²	32.2	7%	0.07	19%	0.192	C	C	.	.	H	α-helix	trans	-67.6	-42.1	179.3	-54.7	0	0	0	0	112	A147 A148 Q155 S430 M433	A147-S151 VanDerWaalsContact O-CB 3.29Å; A147-S151 WeakPolarHBondContact O-CB 3.44Å; A147-S151 PolarHBondContact O-N 3.29Å; A147-S151 VanDerWaalsContact O-N 3.13Å; A147-S151 PolarHBondContact O-OG 3.04Å; A148-S151 PolarHBondContact O-N 3.44Å; S151-Q155 VanDerWaalsContact O-CB 3.27Å; S151-Q155 WeakPolarHBondContact O-CB 3.11Å; S151-Q155 PolarHBondContact O-N 3.21Å; S151-S430 WeakPolarHBondContact O-CB 3.38Å; S151-M433 WeakPolarHBondContact OG-CG 3.47Å
152	I	92.9	Very high	93.3	Very high	4 Å²	4	31 Å²	31	2%	0.021	18%	0.179	C	C	.	.	H	α-helix	trans	-63.8	-46.4	175	-68.3	167.9	0	0	0	110.6	Y132 A148 Q155 N156 P292 P378 S382 L434	Y132-I152 HydrophobicContact CD1-CD1 4.26Å; Y132-I152 HydrophobicContact CD2-CD1 4.32Å; Y132-I152 HydrophobicContact CG-CD1 3.86Å; A148-I152 WeakPolarHBondContact O-CB 3.24Å; A148-I152 WeakPolarHBondContact O-CG1 3.37Å; A148-I152 PolarHBondContact O-N 3.05Å; I152-Q155 PolarHBondContact O-N 3.25Å; I152-N156 PolarHBondContact O-N 3.31Å; I152-N156 PolarHBondContact O-ND2 2.7Å; I152-P292 HydrophobicContact CG1-CB 4.43Å; I152-P292 HydrophobicContact CG1-CG 4.41Å; I152-P292 HydrophobicContact CG2-CB 4.1Å; I152-P378 HydrophobicContact CG2-CB 4.17Å; I152-S382 WeakPolarHBondContact CG2-OG 3.48Å; I152-L434 HydrophobicContact CG1-CD2 3.86Å
153	T	92.3	Very high	93.4	Very high	26 Å²	26	25.1 Å²	25.1	16%	0.16	15%	0.148	C	C	.	.	H	α-helix	trans	-62.3	-48.5	179.2	-57.3	0	0	0	0	110.9	S149 C150 Q155 N156 I157 I379	S149-T153 VanDerWaalsContact O-CB 3.27Å; S149-T153 WeakPolarHBondContact O-CB 3.39Å; S149-T153 PolarHBondContact O-N 2.86Å; S149-T153 PolarHBondContact O-OG1 3.28Å; C150-T153 PolarHBondContact O-N 3.46Å; T153-Q155 PolarHBondContact O-N 3.31Å; T153-N156 PolarHBondContact O-N 3.07Å; T153-I157 HydrophobicContact CG2-CD1 3.72Å; T153-I157 HydrophobicContact CG2-CG1 4.43Å; T153-I157 VanDerWaalsContact O-CB 3.31Å; T153-I157 WeakPolarHBondContact O-CB 3.43Å; T153-I157 VanDerWaalsContact O-CG1 3.26Å; T153-I157 WeakPolarHBondContact O-CG1 3.38Å; T153-I157 PolarHBondContact O-N 2.93Å; T153-I379 HydrophobicContact CG2-CG2 4.1Å
154	M	93.9	Very high	93.5	Very high	74 Å²	74	20.8 Å²	20.8	37%	0.365	12%	0.12	S	C	.	.	H	α-helix	trans	-64.6	-37.1	179.1	-174.9	163.3	67.8	0	0	112.7	C150 G158 S429	C150-M154 VanDerWaalsContact O-CB 3.23Å; C150-M154 WeakPolarHBondContact O-CB 3.42Å; C150-M154 PolarHBondContact O-N 3.44Å; M154-G158 PolarHBondContact O-N 3.08Å; M154-S429 WeakPolarHBondContact CE-OG 3.27Å
155	Q	94.1	Very high	93.6	Very high	6 Å²	6	21.3 Å²	21.3	3%	0.028	12%	0.12	C	C	.	.	H	α-helix	trans	-67.1	-47.3	177.7	-174	52.8	48.1	0	0	112.5	S151 I152 T153 G158 A159 F286 V289 S430 L434	S151-Q155 VanDerWaalsContact O-CB 3.27Å; S151-Q155 WeakPolarHBondContact O-CB 3.11Å; S151-Q155 PolarHBondContact O-N 3.21Å; I152-Q155 PolarHBondContact O-N 3.25Å; T153-Q155 PolarHBondContact O-N 3.31Å; Q155-G158 PolarHBondContact O-N 3.3Å; Q155-A159 PolarHBondContact O-N 2.92Å; Q155-F286 VanDerWaalsContact NE2-CD2 3.28Å; Q155-V289 HydrophobicContact CG-CG1 3.67Å; Q155-V289 HydrophobicContact CG-CG2 4.15Å; Q155-V289 VanDerWaalsContact NE2-CG1 3.29Å; Q155-S430 PolarHBondContact OE1-OG 3Å; Q155-L434 HydrophobicContact CB-CD1 3.73Å; Q155-L434 HydrophobicContact CG-CD1 4Å
156	N	92.8	Very high	93.7	Very high	7 Å²	7	19 Å²	19	4%	0.037	11%	0.11	C	C	.	.	H	α-helix	trans	-73.4	-33.4	-178.9	-68.6	-75.5	0	0	0	111.5	I152 T153 A159 M160 I379	I152-N156 PolarHBondContact O-N 3.31Å; I152-N156 PolarHBondContact O-ND2 2.7Å; T153-N156 PolarHBondContact O-N 3.07Å; N156-A159 PolarHBondContact O-N 3.17Å; N156-M160 WeakPolarHBondContact O-CG 3.25Å; N156-M160 PolarHBondContact O-N 2.92Å; N156-I379 HydrophobicContact CB-CD1 3.59Å; N156-I379 HydrophobicContact CB-CG1 3.45Å; N156-I379 VanDerWaalsContact CB-CG1 3.45Å
157	I	93.4	Very high	93.8	Very high	46 Å²	46	15.2 Å²	15.2	24%	0.236	9%	0.09	C	C	.	.	H	α-helix	trans	-59.8	-46	167.3	-74.5	174.6	0	0	0	110.4	T153 A159 M160 L161 I379 L405 T409	T153-I157 HydrophobicContact CG2-CD1 3.72Å; T153-I157 HydrophobicContact CG2-CG1 4.43Å; T153-I157 VanDerWaalsContact O-CB 3.31Å; T153-I157 WeakPolarHBondContact O-CB 3.43Å; T153-I157 VanDerWaalsContact O-CG1 3.26Å; T153-I157 WeakPolarHBondContact O-CG1 3.38Å; T153-I157 PolarHBondContact O-N 2.93Å; I157-A159 VanDerWaalsContact C-N 3.34Å; I157-A159 PolarHBondContact O-N 2.97Å; I157-M160 PolarHBondContact O-N 3.13Å; I157-M160 VanDerWaalsContact O-N 3.15Å; I157-L161 HydrophobicContact CG2-CD1 3.85Å; I157-L161 HydrophobicContact CG2-CG 4.25Å; I157-L161 VanDerWaalsContact O-CG 3.28Å; I157-L161 WeakPolarHBondContact O-CG 3.09Å; I157-L161 PolarHBondContact O-N 2.87Å; I157-I379 HydrophobicContact CG1-CD1 4.32Å; I157-L405 HydrophobicContact CD1-CD1 4.3Å; I157-L405 HydrophobicContact CG1-CD1 4.17Å; I157-T409 HydrophobicContact CG2-CG2 4.21Å
158	G	94.6	Very high	93.8	Very high	0 Å²	0	14.1 Å²	14.1	0%	0	8%	0.079	C	C	.	.	H	α-helix	trans	-54.7	-47.2	174.6	0	0	0	0	0	112.8	M154 Q155 L161 T162	M154-G158 PolarHBondContact O-N 3.08Å; Q155-G158 PolarHBondContact O-N 3.3Å; G158-L161 PolarHBondContact O-N 3.34Å; G158-T162 WeakPolarHBondContact O-CG2 3.31Å; G158-T162 PolarHBondContact O-N 2.92Å; G158-T162 PolarHBondContact O-OG1 3.45Å
159	A	93.7	Very high	93.8	Very high	12 Å²	12	17.3 Å²	17.3	10%	0.099	9%	0.091	C	C	.	.	H	α-helix	trans	-70.8	-26.3	177.8	0	0	0	0	0	114	Q155 N156 I157 T162 Y163 F286 L375	Q155-A159 PolarHBondContact O-N 2.92Å; N156-A159 PolarHBondContact O-N 3.17Å; I157-A159 VanDerWaalsContact C-N 3.34Å; I157-A159 PolarHBondContact O-N 2.97Å; A159-T162 WeakPolarHBondContact CA-OG1 3.47Å; A159-T162 PolarHBondContact O-OG1 3.13Å; A159-Y163 VanDerWaalsContact O-CD2 3.23Å; A159-Y163 WeakPolarHBondContact O-CD2 3.27Å; A159-Y163 VanDerWaalsContact O-CG 3.25Å; A159-Y163 PolarHBondContact O-N 3.36Å; A159-F286 HydrophobicContact CB-CZ 4.09Å; A159-L375 VanDerWaalsContact C-CD1 3.46Å; A159-L375 HydrophobicContact CB-CD1 3.48Å; A159-L375 VanDerWaalsContact CB-CD1 3.48Å; A159-L375 HydrophobicContact CB-CD2 4.25Å
160	M	93.3	Very high	93.8	Very high	0 Å²	0	17.2 Å²	17.2	0%	0	9%	0.091	C	C	.	.	H	α-helix	trans	-73.3	-40.1	169.1	-74.7	-178.7	62	0	0	112	N156 I157 T162 Y163 L164 V372 L375 L376 I379 L405 T409	N156-M160 WeakPolarHBondContact O-CG 3.25Å; N156-M160 PolarHBondContact O-N 2.92Å; I157-M160 PolarHBondContact O-N 3.13Å; I157-M160 VanDerWaalsContact O-N 3.15Å; M160-T162 VanDerWaalsContact C-N 3.34Å; M160-T162 PolarHBondContact O-N 3.19Å; M160-Y163 PolarHBondContact O-N 3.04Å; M160-L164 WeakPolarHBondContact O-CG 3.36Å; M160-L164 PolarHBondContact O-N 3.24Å; M160-V372 HydrophobicContact CE-CG1 3.92Å; M160-V372 HydrophobicContact CG-CG1 4.49Å; M160-L375 HydrophobicContact CG-CB 3.92Å; M160-L375 HydrophobicContact CG-CD1 3.72Å; M160-L375 HydrophobicContact SD-CB 4.4Å; M160-L376 HydrophobicContact CE-CD1 4.44Å; M160-L376 HydrophobicContact CE-CD2 3.93Å; M160-L376 HydrophobicContact CE-CG 4.06Å; M160-L376 HydrophobicContact SD-CD2 3.86Å; M160-L376 HydrophobicContact SD-CG 3.93Å; M160-I379 HydrophobicContact SD-CD1 3.79Å; M160-L405 HydrophobicContact CE-CD2 3.43Å; M160-L405 VanDerWaalsContact CE-CD2 3.43Å; M160-L405 HydrophobicContact SD-CD2 3.56Å; M160-L405 VanDerWaalsContact SD-CD2 3.56Å; M160-T409 HydrophobicContact CB-CG2 4.44Å
161	L	95.2	Very high	93.8	Very high	10 Å²	10	15.5 Å²	15.5	5%	0.052	8%	0.077	C	C	.	.	H	α-helix	trans	-62.7	-40.2	177	-70.1	167.1	0	0	0	111.6	I157 G158 L164 Y165 T409 L412 V413 I422	I157-L161 HydrophobicContact CG2-CD1 3.85Å; I157-L161 HydrophobicContact CG2-CG 4.25Å; I157-L161 VanDerWaalsContact O-CG 3.28Å; I157-L161 WeakPolarHBondContact O-CG 3.09Å; I157-L161 PolarHBondContact O-N 2.87Å; G158-L161 PolarHBondContact O-N 3.34Å; L161-L164 PolarHBondContact O-N 3.11Å; L161-Y165 VanDerWaalsContact O-CB 3.27Å; L161-Y165 WeakPolarHBondContact O-CB 3.34Å; L161-Y165 PolarHBondContact O-N 3.43Å; L161-T409 HydrophobicContact CD2-CG2 4.19Å; L161-T409 WeakPolarHBondContact CD2-O 3.29Å; L161-T409 HydrophobicContact CG-CG2 4.39Å; L161-L412 HydrophobicContact CD1-CD2 3.67Å; L161-L412 HydrophobicContact CD1-CG 4.2Å; L161-L412 HydrophobicContact CD2-CB 3.88Å; L161-L412 HydrophobicContact CD2-CD2 3.98Å; L161-L412 HydrophobicContact CD2-CG 3.85Å; L161-L412 HydrophobicContact CG-CD2 4.46Å; L161-V413 HydrophobicContact CD2-CB 4.15Å; L161-V413 WeakPolarHBondContact O-CG2 3.49Å; L161-I422 HydrophobicContact CB-CD1 3.87Å; L161-I422 HydrophobicContact CB-CG2 4.26Å
162	T	95.4	Very high	93.6	Very high	0 Å²	0	15.5 Å²	15.5	0%	0	8%	0.077	C	C	.	.	H	α-helix	trans	-67.4	-38.5	176.4	53.1	0	0	0	0	112.2	S85 G158 A159 M160 Y165 I166 F286 I419 I422 F423	S85-T162 WeakPolarHBondContact CB-OG1 3.38Å; S85-T162 WeakPolarHBondContact OG-CB 3.45Å; S85-T162 PolarHBondContact OG-OG1 2.84Å; G158-T162 WeakPolarHBondContact O-CG2 3.31Å; G158-T162 PolarHBondContact O-N 2.92Å; G158-T162 PolarHBondContact O-OG1 3.45Å; A159-T162 WeakPolarHBondContact CA-OG1 3.47Å; A159-T162 PolarHBondContact O-OG1 3.13Å; M160-T162 VanDerWaalsContact C-N 3.34Å; M160-T162 PolarHBondContact O-N 3.19Å; T162-Y165 WeakPolarHBondContact O-CB 3.42Å; T162-Y165 PolarHBondContact O-N 3.27Å; T162-I166 WeakPolarHBondContact O-CD1 3.28Å; T162-I166 VanDerWaalsContact O-CG1 3.27Å; T162-I166 WeakPolarHBondContact O-CG1 3.45Å; T162-I166 PolarHBondContact O-N 2.93Å; T162-F286 HydrophobicContact CG2-CE1 4.43Å; T162-F286 HydrophobicContact CG2-CZ 4.09Å; T162-I419 HydrophobicContact CG2-CD1 4.12Å; T162-I419 HydrophobicContact CG2-CG1 3.85Å; T162-I422 HydrophobicContact CG2-CB 4.02Å; T162-I422 HydrophobicContact CG2-CD1 4.05Å; T162-I422 HydrophobicContact CG2-CG2 3.8Å; T162-F423 HydrophobicContact CG2-CD1 3.97Å; T162-F423 HydrophobicContact CG2-CE1 3.57Å; T162-F423 HydrophobicContact CG2-CZ 4.16Å
163	Y	94.1	Very high	93.4	Very high	5 Å²	5	16.2 Å²	16.2	2%	0.02	8%	0.081	C	C	.	.	H	α-helix	trans	-64.5	-44.9	172.4	-65.9	-25.2	0	0	0	112.9	G84 A159 M160 Y165 I166 I167 V368 T371 V372 L375	G84-Y163 WeakPolarHBondContact CA-OH 3.1Å; A159-Y163 VanDerWaalsContact O-CD2 3.23Å; A159-Y163 WeakPolarHBondContact O-CD2 3.27Å; A159-Y163 VanDerWaalsContact O-CG 3.25Å; A159-Y163 PolarHBondContact O-N 3.36Å; M160-Y163 PolarHBondContact O-N 3.04Å; Y163-Y165 VanDerWaalsContact C-N 3.26Å; Y163-Y165 PolarHBondContact O-N 3.44Å; Y163-I166 HydrophobicContact CD1-CD1 4.39Å; Y163-I166 PolarHBondContact O-N 3.49Å; Y163-I167 WeakPolarHBondContact O-CG1 3.36Å; Y163-I167 PolarHBondContact O-N 2.94Å; Y163-V368 HydrophobicContact CD1-CB 3.56Å; Y163-V368 HydrophobicContact CD1-CG1 3.44Å; Y163-V368 VanDerWaalsContact CD1-CG1 3.44Å; Y163-V368 HydrophobicContact CE1-CB 4.15Å; Y163-V368 HydrophobicContact CE1-CG1 3.8Å; Y163-V368 HydrophobicContact CG-CB 3.81Å; Y163-V368 HydrophobicContact CG-CG1 4.22Å; Y163-T371 HydrophobicContact CE2-CG2 3.7Å; Y163-T371 VanDerWaalsContact OH-CG2 3.26Å; Y163-T371 WeakPolarHBondContact OH-CG2 3.46Å; Y163-V372 HydrophobicContact CD2-CG2 3.66Å; Y163-V372 HydrophobicContact CG-CG2 4.27Å; Y163-L375 HydrophobicContact CD2-CD1 3.73Å; Y163-L375 HydrophobicContact CE2-CD1 3.32Å; Y163-L375 HydrophobicContact CE2-CG 4.02Å
164	L	94.9	Very high	93.3	Very high	1 Å²	1	15.3 Å²	15.3	1%	0.005	8%	0.076	C	C	.	.	H	α-helix	trans	-65.8	-30.8	175.3	-65.7	178.1	0	0	0	111.9	M160 L161 I167 K168 V194 S198 I202 T409 V413	M160-L164 WeakPolarHBondContact O-CG 3.36Å; M160-L164 PolarHBondContact O-N 3.24Å; L161-L164 PolarHBondContact O-N 3.11Å; L164-I167 HydrophobicContact CD2-CD1 4.45Å; L164-I167 PolarHBondContact O-N 3.49Å; L164-K168 WeakPolarHBondContact O-CB 3.37Å; L164-K168 PolarHBondContact O-N 3.11Å; L164-V194 HydrophobicContact CB-CG2 4Å; L164-V194 HydrophobicContact CD2-CG2 4.04Å; L164-V194 WeakPolarHBondContact O-CG2 3.37Å; L164-S198 WeakPolarHBondContact CD2-OG 3.23Å; L164-I202 HydrophobicContact CD2-CD1 3.54Å; L164-T409 WeakPolarHBondContact CD1-OG1 3.15Å; L164-V413 HydrophobicContact CB-CB 4.29Å; L164-V413 HydrophobicContact CB-CG1 3.95Å; L164-V413 HydrophobicContact CB-CG2 4.17Å
165	Y	95.4	Very high	93.1	Very high	18 Å²	18	13.8 Å²	13.8	7%	0.071	7%	0.069	C	C	.	.	H	α-helix	trans	-66.3	-46.6	174.1	-173	-75.7	0	0	0	110.6	L161 T162 Y163 I167 K168 Y169 V413 V416 I419	L161-Y165 VanDerWaalsContact O-CB 3.27Å; L161-Y165 WeakPolarHBondContact O-CB 3.34Å; L161-Y165 PolarHBondContact O-N 3.43Å; T162-Y165 WeakPolarHBondContact O-CB 3.42Å; T162-Y165 PolarHBondContact O-N 3.27Å; Y163-Y165 VanDerWaalsContact C-N 3.26Å; Y163-Y165 PolarHBondContact O-N 3.44Å; Y165-I167 VanDerWaalsContact C-N 3.28Å; Y165-I167 PolarHBondContact O-N 3.5Å; Y165-K168 PolarHBondContact O-N 3.24Å; Y165-Y169 AromaticContact CD1-CD2 3.72Å; Y165-Y169 HydrophobicContact CD1-CD2 3.72Å; Y165-Y169 HydrophobicContact CD1-CE2 4.14Å; Y165-Y169 HydrophobicContact CD2-CD2 4.29Å; Y165-Y169 AromaticContact CD2-CE2 3.93Å; Y165-Y169 HydrophobicContact CD2-CE2 3.93Å; Y165-Y169 AromaticContact CE1-CD2 3.41Å; Y165-Y169 HydrophobicContact CE1-CD2 3.41Å; Y165-Y169 VanDerWaalsContact CE1-CD2 3.41Å; Y165-Y169 AromaticContact CE1-CE2 3.65Å; Y165-Y169 HydrophobicContact CE1-CE2 3.65Å; Y165-Y169 HydrophobicContact CE1-CG 4.12Å; Y165-Y169 HydrophobicContact CE2-CD2 4.04Å; Y165-Y169 AromaticContact CE2-CE2 3.44Å; Y165-Y169 HydrophobicContact CE2-CE2 3.44Å; Y165-Y169 VanDerWaalsContact CE2-CE2 3.44Å; Y165-Y169 HydrophobicContact CG-CD2 4.14Å; Y165-Y169 HydrophobicContact CG-CE2 4.26Å; Y165-Y169 AromaticContact CZ-CD2 3.58Å; Y165-Y169 AromaticContact CZ-CE2 3.26Å; Y165-Y169 AromaticContact CZ-CZ 3.9Å; Y165-Y169 WeakPolarHBondContact O-CD2 3.36Å; Y165-Y169 PolarHBondContact O-N 3.47Å; Y165-Y169 VanDerWaalsContact O-N 3.08Å; Y165-V413 HydrophobicContact CD2-CG2 4.3Å; Y165-V416 HydrophobicContact CD2-CG1 4.2Å; Y165-V416 HydrophobicContact CE2-CG1 4.21Å; Y165-I419 HydrophobicContact CD1-CB 3.86Å; Y165-I419 HydrophobicContact CD1-CD1 4.1Å; Y165-I419 HydrophobicContact CD1-CG1 4.24Å; Y165-I419 HydrophobicContact CD2-CB 4.41Å; Y165-I419 HydrophobicContact CE1-CB 3.85Å; Y165-I419 HydrophobicContact CE1-CG2 4.4Å; Y165-I419 HydrophobicContact CE2-CB 4.37Å; Y165-I419 HydrophobicContact CG-CB 4.17Å; Y165-I419 HydrophobicContact CG-CG1 4.38Å
166	I	94.1	Very high	92.8	Very high	0 Å²	0	15.5 Å²	15.5	0%	0	8%	0.077	C	C	.	.	H	α-helix	trans	-56.9	-45.1	174.7	-65.4	156.2	0	0	0	110.1	L88 T162 Y163 Y169 E170 V364 L365 V368	L88-I166 HydrophobicContact CD1-CD1 3.47Å; L88-I166 VanDerWaalsContact CD1-CD1 3.47Å; L88-I166 HydrophobicContact CD1-CG1 3.78Å; T162-I166 WeakPolarHBondContact O-CD1 3.28Å; T162-I166 VanDerWaalsContact O-CG1 3.27Å; T162-I166 WeakPolarHBondContact O-CG1 3.45Å; T162-I166 PolarHBondContact O-N 2.93Å; Y163-I166 HydrophobicContact CD1-CD1 4.39Å; Y163-I166 PolarHBondContact O-N 3.49Å; I166-Y169 PolarHBondContact O-N 2.85Å; I166-E170 HydrophobicContact CG2-CG 4.35Å; I166-E170 VanDerWaalsContact O-CB 3.28Å; I166-E170 WeakPolarHBondContact O-CB 3.35Å; I166-E170 PolarHBondContact O-N 3.2Å; I166-V364 HydrophobicContact CG2-CG1 4.24Å; I166-L365 HydrophobicContact CG2-CD2 4.43Å; I166-V368 HydrophobicContact CD1-CG1 4.06Å
167	I	94.2	Very high	92.5	Very high	0 Å²	0	19 Å²	19	0%	0	9%	0.092	C	C	.	.	H	α-helix	trans	-61.8	-46.5	176.1	-66.9	163.8	0	0	0	111.5	Y163 L164 Y165 Y169 L171 V194 F197 I202 L365 V368	Y163-I167 WeakPolarHBondContact O-CG1 3.36Å; Y163-I167 PolarHBondContact O-N 2.94Å; L164-I167 HydrophobicContact CD2-CD1 4.45Å; L164-I167 PolarHBondContact O-N 3.49Å; Y165-I167 VanDerWaalsContact C-N 3.28Å; Y165-I167 PolarHBondContact O-N 3.5Å; I167-Y169 VanDerWaalsContact C-N 3.29Å; I167-Y169 PolarHBondContact O-N 3.39Å; I167-L171 HydrophobicContact CG2-CB 4.36Å; I167-L171 HydrophobicContact CG2-CD2 4.08Å; I167-L171 WeakPolarHBondContact O-CB 3.47Å; I167-L171 PolarHBondContact O-N 2.93Å; I167-L171 VanDerWaalsContact O-N 3.14Å; I167-V194 HydrophobicContact CB-CG2 4.5Å; I167-V194 HydrophobicContact CG2-CG2 4.22Å; I167-F197 HydrophobicContact CD1-CD1 4.04Å; I167-F197 HydrophobicContact CD1-CE1 3.86Å; I167-F197 HydrophobicContact CG2-CB 4.38Å; I167-F197 HydrophobicContact CG2-CD1 3.94Å; I167-F197 HydrophobicContact CG2-CG 4.22Å; I167-I202 HydrophobicContact CD1-CD1 3.94Å; I167-L365 HydrophobicContact CB-CD2 4.37Å; I167-L365 HydrophobicContact CG1-CD2 3.87Å; I167-V368 HydrophobicContact CD1-CG2 4.27Å; I167-V368 HydrophobicContact CG1-CG2 4.14Å
168	K	93.9	Very high	92.2	Very high	16 Å²	16	23.4 Å²	23.4	7%	0.07	11%	0.11	C	C	.	.	H	α-helix	trans	-55.7	-38.7	178.4	167.5	174.2	165.3	162.1	0	113	L164 Y165 P172 G190 D191 V194 I414	L164-K168 WeakPolarHBondContact O-CB 3.37Å; L164-K168 PolarHBondContact O-N 3.11Å; Y165-K168 PolarHBondContact O-N 3.24Å; K168-P172 VanDerWaalsContact O-CD 3.31Å; K168-P172 WeakPolarHBondContact O-CD 3.42Å; K168-P172 WeakPolarHBondContact O-CG 3.46Å; K168-G190 WeakPolarHBondContact O-CA 3.32Å; K168-D191 WeakPolarHBondContact CD-OD1 3.23Å; K168-D191 WeakPolarHBondContact CE-OD1 3.32Å; K168-D191 IonicContact NZ-OD1 2.59Å; K168-D191 PolarHBondContact NZ-OD1 2.92Å; K168-D191 IonicContact NZ-OD2 3.64Å; K168-V194 HydrophobicContact CB-CB 4.13Å; K168-V194 HydrophobicContact CB-CG1 4.4Å; K168-V194 HydrophobicContact CB-CG2 4.39Å; K168-I414 PolarHBondContact NZ-O 2.9Å
169	Y	91.8	Very high	91.7	Very high	66 Å²	66	26.3 Å²	26.3	26%	0.259	13%	0.133	S	C	.	.	H	α-helix	trans	-95.8	-35	-175.5	-76.6	-90.9	0	0	0	114.1	Y165 I166 I167	Y165-Y169 AromaticContact CD1-CD2 3.72Å; Y165-Y169 HydrophobicContact CD1-CD2 3.72Å; Y165-Y169 HydrophobicContact CD1-CE2 4.14Å; Y165-Y169 HydrophobicContact CD2-CD2 4.29Å; Y165-Y169 AromaticContact CD2-CE2 3.93Å; Y165-Y169 HydrophobicContact CD2-CE2 3.93Å; Y165-Y169 AromaticContact CE1-CD2 3.41Å; Y165-Y169 HydrophobicContact CE1-CD2 3.41Å; Y165-Y169 VanDerWaalsContact CE1-CD2 3.41Å; Y165-Y169 AromaticContact CE1-CE2 3.65Å; Y165-Y169 HydrophobicContact CE1-CE2 3.65Å; Y165-Y169 HydrophobicContact CE1-CG 4.12Å; Y165-Y169 HydrophobicContact CE2-CD2 4.04Å; Y165-Y169 AromaticContact CE2-CE2 3.44Å; Y165-Y169 HydrophobicContact CE2-CE2 3.44Å; Y165-Y169 VanDerWaalsContact CE2-CE2 3.44Å; Y165-Y169 HydrophobicContact CG-CD2 4.14Å; Y165-Y169 HydrophobicContact CG-CE2 4.26Å; Y165-Y169 AromaticContact CZ-CD2 3.58Å; Y165-Y169 AromaticContact CZ-CE2 3.26Å; Y165-Y169 AromaticContact CZ-CZ 3.9Å; Y165-Y169 WeakPolarHBondContact O-CD2 3.36Å; Y165-Y169 PolarHBondContact O-N 3.47Å; Y165-Y169 VanDerWaalsContact O-N 3.08Å; I166-Y169 PolarHBondContact O-N 2.85Å; I167-Y169 VanDerWaalsContact C-N 3.29Å; I167-Y169 PolarHBondContact O-N 3.39Å
170	E	92.3	Very high	91.1	Very high	0 Å²	0	28.8 Å²	28.8	0%	0	16%	0.16	C	C	.	.	H	α-helix	trans	-92.9	-33.1	-173.7	-67.3	-66.7	121.7	0	0	114	I166 V173 V174 L344 H345 R361 L365	I166-E170 HydrophobicContact CG2-CG 4.35Å; I166-E170 VanDerWaalsContact O-CB 3.28Å; I166-E170 WeakPolarHBondContact O-CB 3.35Å; I166-E170 PolarHBondContact O-N 3.2Å; E170-V173 PolarHBondContact O-N 3.1Å; E170-V174 PolarHBondContact O-N 3.15Å; E170-L344 HydrophobicContact CG-CD2 4.14Å; E170-H345 WeakPolarHBondContact OE1-CA 3.5Å; E170-H345 PolarHBondContact OE1-N 2.89Å; E170-R361 IonicContact OE1-NH1 2.7Å; E170-R361 PolarHBondContact OE1-NH1 3.39Å; E170-R361 WeakPolarHBondContact OE2-CD 3.47Å; E170-R361 WeakPolarHBondContact OE2-CG 3.35Å; E170-R361 IonicContact OE2-CZ 3.7Å; E170-R361 IonicContact OE2-NE 3.76Å; E170-R361 IonicContact OE2-NH1 2.66Å; E170-R361 PolarHBondContact OE2-NH1 3.04Å; E170-L365 HydrophobicContact CB-CD1 4.39Å; E170-L365 HydrophobicContact CB-CD2 4.21Å; E170-L365 HydrophobicContact CB-CG 4.44Å
171	L	92.5	Very high	90	Very high	24 Å²	24	29.8 Å²	29.8	13%	0.126	17%	0.168	C	C	.	.	H	α-helix	trans	-60.7	-40	176.3	-174.3	60.7	0	0	0	113.1	I167 V173 V174 I175 L193 F197 L365	I167-L171 HydrophobicContact CG2-CB 4.36Å; I167-L171 HydrophobicContact CG2-CD2 4.08Å; I167-L171 WeakPolarHBondContact O-CB 3.47Å; I167-L171 PolarHBondContact O-N 2.93Å; I167-L171 VanDerWaalsContact O-N 3.14Å; L171-V173 VanDerWaalsContact C-N 3.3Å; L171-V173 PolarHBondContact O-N 3.1Å; L171-V174 PolarHBondContact O-N 3.4Å; L171-I175 HydrophobicContact CD1-CD1 4.07Å; L171-I175 HydrophobicContact CD1-CG1 4.32Å; L171-I175 HydrophobicContact CG-CD1 3.87Å; L171-I175 WeakPolarHBondContact O-CG1 3.37Å; L171-I175 PolarHBondContact O-N 2.91Å; L171-L193 HydrophobicContact CD2-CB 4.41Å; L171-F197 HydrophobicContact CD2-CB 4.03Å; L171-F197 HydrophobicContact CD2-CD2 3.73Å; L171-F197 HydrophobicContact CD2-CE2 4.45Å; L171-F197 HydrophobicContact CD2-CG 4Å; L171-L365 HydrophobicContact CB-CD1 4.49Å; L171-L365 HydrophobicContact CD1-CD1 4.43Å
172	P	91.1	Very high	88.8	Confident	11 Å²	11	34.6 Å²	34.6	7%	0.071	20%	0.198	C	C	.	.	H	α-helix	trans	-51.9	-43.2	170.3	-29.8	34.7	0	0	0	114.6	K168 I175 Q176 I188 L193	K168-P172 VanDerWaalsContact O-CD 3.31Å; K168-P172 WeakPolarHBondContact O-CD 3.42Å; K168-P172 WeakPolarHBondContact O-CG 3.46Å; P172-I175 PolarHBondContact O-N 2.87Å; P172-Q176 WeakPolarHBondContact O-CB 3.4Å; P172-Q176 VanDerWaalsContact O-CG 3.26Å; P172-Q176 WeakPolarHBondContact O-CG 3.36Å; P172-Q176 PolarHBondContact O-N 3.34Å; P172-I188 HydrophobicContact CB-CG2 4.47Å; P172-I188 WeakPolarHBondContact CB-O 3.45Å; P172-L193 HydrophobicContact CB-CD1 4.23Å; P172-L193 HydrophobicContact CG-CD1 3.81Å
173	V	88.6	Confident	87.5	Confident	18 Å²	18	42.6 Å²	42.6	11%	0.109	24%	0.235	C	C	.	.	H	α-helix	trans	-74.8	-35.9	-174	-171.3	0	0	0	0	110.9	E170 L171 I175 F177	E170-V173 PolarHBondContact O-N 3.1Å; L171-V173 VanDerWaalsContact C-N 3.3Å; L171-V173 PolarHBondContact O-N 3.1Å; V173-I175 VanDerWaalsContact C-N 3.34Å; V173-F177 PolarHBondContact O-N 2.92Å; V173-F177 VanDerWaalsContact O-N 3.16Å
174	V	90.3	Very high	86.4	Confident	7 Å²	7	46.2 Å²	46.2	4%	0.042	28%	0.275	C	S	.	.	H	α-helix	trans	-60.7	-44.4	170.1	174	0	0	0	0	110.9	E170 L171 F177 F178 L358 R361 L362 L365	E170-V174 PolarHBondContact O-N 3.15Å; L171-V174 PolarHBondContact O-N 3.4Å; V174-F177 PolarHBondContact O-N 2.98Å; V174-F178 HydrophobicContact CG1-CD2 3.92Å; V174-F178 HydrophobicContact CG1-CE2 3.89Å; V174-F178 VanDerWaalsContact O-CD2 3.26Å; V174-F178 WeakPolarHBondContact O-CD2 3.28Å; V174-F178 PolarHBondContact O-N 3.41Å; V174-L358 HydrophobicContact CB-CD1 4.37Å; V174-L358 HydrophobicContact CG1-CD1 4.41Å; V174-L358 HydrophobicContact CG2-CD1 4.11Å; V174-R361 HydrophobicContact CG2-CB 3.8Å; V174-L362 HydrophobicContact CG1-CD2 3.66Å; V174-L362 HydrophobicContact CG1-CG 4.27Å; V174-L365 HydrophobicContact CG2-CD1 3.88Å
175	I	89.4	Confident	85.8	Confident	43 Å²	43	50 Å²	50	22%	0.221	29%	0.292	C	S	.	.	H	α-helix	trans	-69	-41.7	179.6	-69	170.7	0	0	0	111.7	L171 P172 V173 F177 F178 A179 Y187 L193	L171-I175 HydrophobicContact CD1-CD1 4.07Å; L171-I175 HydrophobicContact CD1-CG1 4.32Å; L171-I175 HydrophobicContact CG-CD1 3.87Å; L171-I175 WeakPolarHBondContact O-CG1 3.37Å; L171-I175 PolarHBondContact O-N 2.91Å; P172-I175 PolarHBondContact O-N 2.87Å; V173-I175 VanDerWaalsContact C-N 3.34Å; I175-F177 VanDerWaalsContact C-N 3.31Å; I175-F177 PolarHBondContact O-N 3.37Å; I175-F178 PolarHBondContact O-N 3.27Å; I175-A179 VanDerWaalsContact O-CB 3.23Å; I175-A179 WeakPolarHBondContact O-CB 3.31Å; I175-A179 PolarHBondContact O-N 2.8Å; I175-Y187 HydrophobicContact CG2-CD2 3.92Å; I175-Y187 HydrophobicContact CG2-CE2 4.48Å; I175-L193 HydrophobicContact CD1-CD1 3.9Å; I175-L193 HydrophobicContact CD1-CD2 3.54Å; I175-L193 HydrophobicContact CD1-CG 4.38Å
176	Q	87.9	Confident	85.2	Confident	42 Å²	42	57 Å²	57	20%	0.196	32%	0.319	C	S	.	.	H	α-helix	trans	-52	-49.3	173	-78.2	164.8	28.5	0	0	111.4	P172 G180 A181 I188	P172-Q176 WeakPolarHBondContact O-CB 3.4Å; P172-Q176 VanDerWaalsContact O-CG 3.26Å; P172-Q176 WeakPolarHBondContact O-CG 3.36Å; P172-Q176 PolarHBondContact O-N 3.34Å; Q176-G180 WeakPolarHBondContact O-CA 3.38Å; Q176-G180 PolarHBondContact O-N 3.06Å; Q176-A181 PolarHBondContact O-N 2.64Å; Q176-I188 HydrophobicContact CG-CD1 4.08Å; Q176-I188 HydrophobicContact CG-CG1 4.37Å; Q176-I188 HydrophobicContact CG-CG2 3.72Å
177	F	85.9	Confident	84.6	Confident	81 Å²	81	59.9 Å²	59.9	36%	0.355	33%	0.33	S	S	.	.	H	α-helix	trans	-62.2	-47	-178.7	-172.8	-80.6	0	0	0	112.5	V173 V174 I175 D353 I355 L358	V173-F177 PolarHBondContact O-N 2.92Å; V173-F177 VanDerWaalsContact O-N 3.16Å; V174-F177 PolarHBondContact O-N 2.98Å; I175-F177 VanDerWaalsContact C-N 3.31Å; I175-F177 PolarHBondContact O-N 3.37Å; F177-D353 HydrophobicContact CE2-CB 4.38Å; F177-I355 HydrophobicContact CZ-CG1 4.45Å; F177-L358 HydrophobicContact CB-CD1 4.01Å; F177-L358 HydrophobicContact CD1-CD1 4.32Å; F177-L358 HydrophobicContact CD1-CD2 3.33Å; F177-L358 HydrophobicContact CD1-CG 4.45Å; F177-L358 HydrophobicContact CD2-CD2 4.34Å; F177-L358 HydrophobicContact CE1-CD2 3.44Å; F177-L358 VanDerWaalsContact CE1-CD2 3.44Å; F177-L358 HydrophobicContact CE2-CD2 4.41Å; F177-L358 HydrophobicContact CG-CD1 4.08Å; F177-L358 HydrophobicContact CG-CD2 3.83Å; F177-L358 HydrophobicContact CZ-CD2 4Å
178	F	87	Confident	84.2	Confident	138 Å²	138	60.9 Å²	60.9	61%	0.605	34%	0.335	S	S	*	.	H	α-helix	trans	-76.1	-30.4	-178	-75.7	-63.3	0	0	0	114.2	V174 I175 L358 L362	V174-F178 HydrophobicContact CG1-CD2 3.92Å; V174-F178 HydrophobicContact CG1-CE2 3.89Å; V174-F178 VanDerWaalsContact O-CD2 3.26Å; V174-F178 WeakPolarHBondContact O-CD2 3.28Å; V174-F178 PolarHBondContact O-N 3.41Å; I175-F178 PolarHBondContact O-N 3.27Å; F178-L358 HydrophobicContact CE2-CD2 4.23Å; F178-L358 HydrophobicContact CZ-CD2 4Å; F178-L362 HydrophobicContact CE2-CD1 4.16Å; F178-L362 HydrophobicContact CZ-CD1 4.27Å
179	A	85.1	Confident	84	Confident	60 Å²	60	63.2 Å²	63.2	50%	0.496	35%	0.348	S	S	.	.	H	α-helix	trans	-88.4	-14.4	-179.8	0	0	0	0	0	113.5	I175 A181 Y187	I175-A179 VanDerWaalsContact O-CB 3.23Å; I175-A179 WeakPolarHBondContact O-CB 3.31Å; I175-A179 PolarHBondContact O-N 2.8Å; A179-A181 HydrophobicContact CB-CB 3.8Å; A179-A181 PolarHBondContact O-N 2.96Å; A179-Y187 HydrophobicContact CB-CE2 4.3Å
180	G	79.8	Confident	83.9	Confident	65 Å²	65	60.5 Å²	60.5	67%	0.67	34%	0.341	S	S	*	.	T	Hydrogen-bonded Turn	trans	62.6	21.7	-170.7	0	0	0	0	0	113.1	Q176	Q176-G180 WeakPolarHBondContact O-CA 3.38Å; Q176-G180 PolarHBondContact O-N 3.06Å
181	A	72.1	Confident	83.9	Confident	20 Å²	20	62.8 Å²	62.8	17%	0.165	35%	0.353	C	S	.	.	P	Polyproline II helix	trans	-89	138.5	-161.3	0	0	0	0	0	113	Q176 A179 Y187 I188	Q176-A181 PolarHBondContact O-N 2.64Å; A179-A181 HydrophobicContact CB-CB 3.8Å; A179-A181 PolarHBondContact O-N 2.96Å; A181-Y187 HydrophobicContact CB-CE2 3.71Å; A181-Y187 VanDerWaalsContact CB-OH 3.32Å; A181-Y187 WeakPolarHBondContact CB-OH 3.24Å; A181-I188 HydrophobicContact CB-CD1 3.7Å; A181-I188 HydrophobicContact CB-CG1 4.49Å
182	T	70	Confident	83.9	Confident	111 Å²	111	68.6 Å²	68.6	68%	0.681	37%	0.374	S	S	*	.	P	Polyproline II helix	trans	-94.5	171	-173.7	52.5	0	0	0	0	113	G184 I188	T182-G184 PolarHBondContact O-N 3.44Å; T182-I188 WeakPolarHBondContact O-CD1 3.44Å
183	H	66.8	Low	84	Confident	168 Å²	168	68.2 Å²	68.2	78%	0.778	37%	0.372	S	S	*	.	T	Hydrogen-bonded Turn	trans	-59.4	127.4	-174.1	-73.1	-88.8	0	0	0	113.4
184	G	70.8	Confident	84.3	Confident	82 Å²	82	67.4 Å²	67.4	85%	0.845	37%	0.366	S	S	*	.	T	Hydrogen-bonded Turn	trans	126.7	-17.7	171.8	0	0	0	0	0	114.7	T182	T182-G184 PolarHBondContact O-N 3.44Å
185	E	82.5	Confident	84.5	Confident	80 Å²	80	70.5 Å²	70.5	37%	0.374	38%	0.382	S	S	.	.			trans	-68.8	137.5	-176	-74.7	-84.2	-136	0	0	113.9	Y187 I188	E185-Y187 VanDerWaalsContact C-N 3.3Å; E185-Y187 HydrophobicContact CB-CD1 4.14Å; E185-Y187 HydrophobicContact CB-CE1 3.71Å; E185-Y187 HydrophobicContact CB-CE2 4.14Å; E185-Y187 VanDerWaalsContact CD-CZ 3.49Å; E185-Y187 VanDerWaalsContact CD-OH 3.23Å; E185-Y187 HydrophobicContact CG-CE1 3.81Å; E185-Y187 HydrophobicContact CG-CE2 4.48Å; E185-Y187 WeakPolarHBondContact CG-OH 3.31Å; E185-Y187 PolarHBondContact O-N 3.46Å; E185-Y187 VanDerWaalsContact OE1-CE1 3.22Å; E185-Y187 WeakPolarHBondContact OE1-CE1 3.31Å; E185-Y187 PolarHBondContact OE1-OH 2.94Å; E185-Y187 WeakPolarHBondContact OE2-CE1 3.45Å; E185-I188 HydrophobicContact CB-CB 4.49Å; E185-I188 HydrophobicContact CB-CD1 3.72Å; E185-I188 HydrophobicContact CB-CG1 3.85Å; E185-I188 HydrophobicContact CG-CD1 4.41Å; E185-I188 WeakPolarHBondContact O-CB 3.4Å; E185-I188 PolarHBondContact O-N 2.94Å
186	W	83.4	Confident	84.7	Confident	165 Å²	165	72.6 Å²	72.6	63%	0.625	39%	0.392	S	S	*	.	G	3₁₀ helix	trans	-64.1	-34.5	-175.9	67.9	-88.5	0	0	0	112.8	I188 N189	W186-I188 PolarHBondContact O-N 2.84Å; W186-N189 WeakPolarHBondContact O-CB 3.45Å; W186-N189 PolarHBondContact O-N 2.91Å
187	Y	81.6	Confident	85	Confident	60 Å²	60	72.6 Å²	72.6	24%	0.235	39%	0.392	C	S	.	.	G	3₁₀ helix	trans	-77.8	3.3	177.7	60.4	-97.1	0	0	0	113.5	I175 A179 A181 E185 L193	I175-Y187 HydrophobicContact CG2-CD2 3.92Å; I175-Y187 HydrophobicContact CG2-CE2 4.48Å; A179-Y187 HydrophobicContact CB-CE2 4.3Å; A181-Y187 HydrophobicContact CB-CE2 3.71Å; A181-Y187 VanDerWaalsContact CB-OH 3.32Å; A181-Y187 WeakPolarHBondContact CB-OH 3.24Å; E185-Y187 VanDerWaalsContact C-N 3.3Å; E185-Y187 HydrophobicContact CB-CD1 4.14Å; E185-Y187 HydrophobicContact CB-CE1 3.71Å; E185-Y187 HydrophobicContact CB-CE2 4.14Å; E185-Y187 VanDerWaalsContact CD-CZ 3.49Å; E185-Y187 VanDerWaalsContact CD-OH 3.23Å; E185-Y187 HydrophobicContact CG-CE1 3.81Å; E185-Y187 HydrophobicContact CG-CE2 4.48Å; E185-Y187 WeakPolarHBondContact CG-OH 3.31Å; E185-Y187 PolarHBondContact O-N 3.46Å; E185-Y187 VanDerWaalsContact OE1-CE1 3.22Å; E185-Y187 WeakPolarHBondContact OE1-CE1 3.31Å; E185-Y187 PolarHBondContact OE1-OH 2.94Å; E185-Y187 WeakPolarHBondContact OE2-CE1 3.45Å; Y187-L193 WeakPolarHBondContact O-CD1 3.43Å
188	I	85.1	Confident	85.3	Confident	22 Å²	22	68.8 Å²	68.8	11%	0.113	38%	0.375	C	S	.	.	G	3₁₀ helix	trans	-101.8	-15.3	169.9	-56.2	178.8	0	0	0	110.9	P172 Q176 A181 T182 E185 W186 G190	P172-I188 HydrophobicContact CB-CG2 4.47Å; P172-I188 WeakPolarHBondContact CB-O 3.45Å; Q176-I188 HydrophobicContact CG-CD1 4.08Å; Q176-I188 HydrophobicContact CG-CG1 4.37Å; Q176-I188 HydrophobicContact CG-CG2 3.72Å; A181-I188 HydrophobicContact CB-CD1 3.7Å; A181-I188 HydrophobicContact CB-CG1 4.49Å; T182-I188 WeakPolarHBondContact O-CD1 3.44Å; E185-I188 HydrophobicContact CB-CB 4.49Å; E185-I188 HydrophobicContact CB-CD1 3.72Å; E185-I188 HydrophobicContact CB-CG1 3.85Å; E185-I188 HydrophobicContact CG-CD1 4.41Å; E185-I188 WeakPolarHBondContact O-CB 3.4Å; E185-I188 PolarHBondContact O-N 2.94Å; W186-I188 PolarHBondContact O-N 2.84Å; I188-G190 PolarHBondContact O-N 3.42Å
189	N	89.8	Confident	85.6	Confident	64 Å²	64	66.1 Å²	66.1	34%	0.342	37%	0.369	S	S	.	.			trans	-72.4	114.6	-179.7	-175.5	-24.5	0	0	0	111.1	W186 D191 Y192 L193	W186-N189 WeakPolarHBondContact O-CB 3.45Å; W186-N189 PolarHBondContact O-N 2.91Å; N189-D191 VanDerWaalsContact C-N 3.25Å; N189-D191 PolarHBondContact O-N 2.92Å; N189-D191 PolarHBondContact OD1-N 3.45Å; N189-Y192 HydrophobicContact CB-CD2 3.82Å; N189-Y192 PolarHBondContact O-N 3.33Å; N189-L193 WeakPolarHBondContact O-CB 3.34Å; N189-L193 WeakPolarHBondContact O-CG 3.44Å; N189-L193 PolarHBondContact O-N 3.42Å
190	G	89.9	Confident	86	Confident	10 Å²	10	68.6 Å²	68.6	10%	0.103	38%	0.375	C	S	.	.	H	α-helix	trans	-55.5	-32.3	-180	0	0	0	0	0	115.1	K168 I188 V194	K168-G190 WeakPolarHBondContact O-CA 3.32Å; I188-G190 PolarHBondContact O-N 3.42Å; G190-V194 WeakPolarHBondContact O-CB 3.48Å; G190-V194 WeakPolarHBondContact O-CG1 3.39Å; G190-V194 PolarHBondContact O-N 2.7Å
191	D	92.8	Very high	86.6	Confident	48 Å²	48	67.7 Å²	67.7	26%	0.257	36%	0.356	S	S	.	.	H	α-helix	trans	-73.5	-35.7	-180	-67.6	-46.8	0	0	0	112.2	K168 N189 I195 I414	K168-D191 WeakPolarHBondContact CD-OD1 3.23Å; K168-D191 WeakPolarHBondContact CE-OD1 3.32Å; K168-D191 IonicContact NZ-OD1 2.59Å; K168-D191 PolarHBondContact NZ-OD1 2.92Å; K168-D191 IonicContact NZ-OD2 3.64Å; N189-D191 VanDerWaalsContact C-N 3.25Å; N189-D191 PolarHBondContact O-N 2.92Å; N189-D191 PolarHBondContact OD1-N 3.45Å; D191-I195 WeakPolarHBondContact O-CD1 3.33Å; D191-I195 WeakPolarHBondContact O-CG1 3.33Å; D191-I414 HydrophobicContact CB-CG1 4.16Å; D191-I414 HydrophobicContact CB-CG2 4.39Å; D191-I414 WeakPolarHBondContact OD1-CG1 3.47Å
192	Y	92.3	Very high	87.5	Confident	145 Å²	145	66.8 Å²	66.8	57%	0.569	35%	0.348	S	S	*	.	H	α-helix	trans	-76.2	-38.6	171.5	-63.8	-47.1	0	0	0	111.6	N189 I195 M196	N189-Y192 HydrophobicContact CB-CD2 3.82Å; N189-Y192 PolarHBondContact O-N 3.33Å; Y192-I195 PolarHBondContact O-N 2.94Å; Y192-M196 WeakPolarHBondContact O-CB 3.09Å; Y192-M196 PolarHBondContact O-N 3.22Å
193	L	92.6	Very high	88.5	Confident	4 Å²	4	63 Å²	63	2%	0.021	32%	0.323	C	S	.	.	H	α-helix	trans	-63.2	-43.3	178.2	-78.9	173.2	0	0	0	112.9	L171 P172 I175 Y187 N189 I195 M196 F197	L171-L193 HydrophobicContact CD2-CB 4.41Å; P172-L193 HydrophobicContact CB-CD1 4.23Å; P172-L193 HydrophobicContact CG-CD1 3.81Å; I175-L193 HydrophobicContact CD1-CD1 3.9Å; I175-L193 HydrophobicContact CD1-CD2 3.54Å; I175-L193 HydrophobicContact CD1-CG 4.38Å; Y187-L193 WeakPolarHBondContact O-CD1 3.43Å; N189-L193 WeakPolarHBondContact O-CB 3.34Å; N189-L193 WeakPolarHBondContact O-CG 3.44Å; N189-L193 PolarHBondContact O-N 3.42Å; L193-I195 VanDerWaalsContact C-N 3.33Å; L193-I195 PolarHBondContact O-N 3.09Å; L193-M196 HydrophobicContact CD2-CE 3.98Å; L193-M196 PolarHBondContact O-N 3.09Å; L193-F197 WeakPolarHBondContact O-CB 3.37Å; L193-F197 PolarHBondContact O-N 3.32Å
194	V	94.8	Very high	89.6	Confident	0 Å²	0	57.8 Å²	57.8	0%	0	31%	0.305	C	S	.	.	H	α-helix	trans	-65.2	-37.3	-179.8	71.8	0	0	0	0	111.8	L164 I167 K168 G190 S198 N410 V413 I414	L164-V194 HydrophobicContact CB-CG2 4Å; L164-V194 HydrophobicContact CD2-CG2 4.04Å; L164-V194 WeakPolarHBondContact O-CG2 3.37Å; I167-V194 HydrophobicContact CB-CG2 4.5Å; I167-V194 HydrophobicContact CG2-CG2 4.22Å; K168-V194 HydrophobicContact CB-CB 4.13Å; K168-V194 HydrophobicContact CB-CG1 4.4Å; K168-V194 HydrophobicContact CB-CG2 4.39Å; G190-V194 WeakPolarHBondContact O-CB 3.48Å; G190-V194 WeakPolarHBondContact O-CG1 3.39Å; G190-V194 PolarHBondContact O-N 2.7Å; V194-S198 WeakPolarHBondContact O-CB 3.49Å; V194-S198 PolarHBondContact O-N 2.92Å; V194-S198 PolarHBondContact O-OG 3.33Å; V194-N410 PolarHBondContact O-OD1 3.42Å; V194-V413 HydrophobicContact CG1-CG1 4.39Å; V194-V413 HydrophobicContact CG2-CG1 4.38Å; V194-I414 HydrophobicContact CG1-CG1 4.46Å
195	I	94.6	Very high	90.4	Very high	73 Å²	73	56.7 Å²	56.7	37%	0.374	28%	0.279	S	S	.	.	H	α-helix	trans	-64.9	-51.7	172.8	-62.5	169	0	0	0	110.2	D191 Y192 L193 F197 S198 V199 N410 I414	D191-I195 WeakPolarHBondContact O-CD1 3.33Å; D191-I195 WeakPolarHBondContact O-CG1 3.33Å; Y192-I195 PolarHBondContact O-N 2.94Å; L193-I195 VanDerWaalsContact C-N 3.33Å; L193-I195 PolarHBondContact O-N 3.09Å; I195-F197 PolarHBondContact O-N 2.88Å; I195-S198 PolarHBondContact O-N 3.35Å; I195-V199 WeakPolarHBondContact O-CG2 3.29Å; I195-V199 PolarHBondContact O-N 3.35Å; I195-N410 WeakPolarHBondContact CA-OD1 3.44Å; I195-I414 HydrophobicContact CD1-CD1 3.83Å; I195-I414 HydrophobicContact CG1-CD1 4.13Å
196	M	93.5	Very high	90.5	Very high	87 Å²	87	53.3 Å²	53.3	43%	0.429	27%	0.265	S	S	.	.	H	α-helix	trans	-60.5	-45.8	-177.6	-172.7	-175.6	75.6	0	0	111.6	Y192 L193 V199 N200	Y192-M196 WeakPolarHBondContact O-CB 3.09Å; Y192-M196 PolarHBondContact O-N 3.22Å; L193-M196 HydrophobicContact CD2-CE 3.98Å; L193-M196 PolarHBondContact O-N 3.09Å; M196-V199 PolarHBondContact O-N 3.32Å; M196-N200 WeakPolarHBondContact O-CB 3.43Å; M196-N200 PolarHBondContact O-N 2.7Å; M196-N200 PolarHBondContact O-ND2 2.97Å
197	F	94	Very high	90.5	Very high	42 Å²	42	48 Å²	48	18%	0.184	25%	0.248	C	C	.	.	H	α-helix	trans	-66.3	-38.4	177.1	-170.3	-90	0	0	0	111.7	I167 L171 L193 I195 V199 V201 I202 T369	I167-F197 HydrophobicContact CD1-CD1 4.04Å; I167-F197 HydrophobicContact CD1-CE1 3.86Å; I167-F197 HydrophobicContact CG2-CB 4.38Å; I167-F197 HydrophobicContact CG2-CD1 3.94Å; I167-F197 HydrophobicContact CG2-CG 4.22Å; L171-F197 HydrophobicContact CD2-CB 4.03Å; L171-F197 HydrophobicContact CD2-CD2 3.73Å; L171-F197 HydrophobicContact CD2-CE2 4.45Å; L171-F197 HydrophobicContact CD2-CG 4Å; L193-F197 WeakPolarHBondContact O-CB 3.37Å; L193-F197 PolarHBondContact O-N 3.32Å; I195-F197 PolarHBondContact O-N 2.88Å; F197-V199 PolarHBondContact O-N 3.42Å; F197-V201 HydrophobicContact CD1-CB 4.36Å; F197-V201 HydrophobicContact CD2-CB 4.42Å; F197-V201 HydrophobicContact CD2-CG2 3.92Å; F197-V201 HydrophobicContact CE1-CB 4.15Å; F197-V201 HydrophobicContact CE1-CG1 4.27Å; F197-V201 HydrophobicContact CE2-CB 4.22Å; F197-V201 HydrophobicContact CE2-CG1 4.4Å; F197-V201 HydrophobicContact CE2-CG2 3.84Å; F197-V201 HydrophobicContact CG-CB 4.49Å; F197-V201 HydrophobicContact CG-CG2 4.36Å; F197-V201 HydrophobicContact CZ-CB 4.08Å; F197-V201 HydrophobicContact CZ-CG1 3.97Å; F197-V201 HydrophobicContact CZ-CG2 4.21Å; F197-V201 WeakPolarHBondContact O-CA 3.06Å; F197-V201 WeakPolarHBondContact O-CB 3.46Å; F197-V201 PolarHBondContact O-N 3.41Å; F197-I202 HydrophobicContact CD1-CD1 4.05Å; F197-I202 HydrophobicContact CD1-CG1 4.03Å; F197-I202 HydrophobicContact CE1-CD1 4.25Å; F197-I202 HydrophobicContact CE1-CG1 4.03Å; F197-I202 PolarHBondContact O-N 3.1Å; F197-T369 HydrophobicContact CE1-CG2 3.83Å; F197-T369 WeakPolarHBondContact CE1-OG1 3.27Å; F197-T369 HydrophobicContact CZ-CG2 3.9Å; F197-T369 WeakPolarHBondContact CZ-OG1 3.18Å
198	S	93.4	Very high	90.4	Very high	1 Å²	1	50.6 Å²	50.6	1%	0.007	27%	0.266	C	S	.	.	I	π-helix	trans	-61.6	-43.9	174.9	-68.5	0	0	0	0	112.5	L164 V194 I195 I202 L203 N410	L164-S198 WeakPolarHBondContact CD2-OG 3.23Å; V194-S198 WeakPolarHBondContact O-CB 3.49Å; V194-S198 PolarHBondContact O-N 2.92Å; V194-S198 PolarHBondContact O-OG 3.33Å; I195-S198 PolarHBondContact O-N 3.35Å; S198-I202 PolarHBondContact O-N 2.9Å; S198-L203 WeakPolarHBondContact O-CB 3.23Å; S198-L203 PolarHBondContact O-N 3.41Å; S198-N410 VanDerWaalsContact CB-ND2 3.31Å; S198-N410 WeakPolarHBondContact CB-ND2 3.5Å; S198-N410 PolarHBondContact OG-ND2 3.4Å; S198-N410 PolarHBondContact OG-OD1 3.01Å
199	V	93.1	Very high	89.2	Confident	81 Å²	81	56.1 Å²	56.1	49%	0.491	29%	0.289	S	S	.	.	I	π-helix	trans	-73.3	-41	-179.5	173.4	0	0	0	0	112.3	I195 M196 F197 P204	I195-V199 WeakPolarHBondContact O-CG2 3.29Å; I195-V199 PolarHBondContact O-N 3.35Å; M196-V199 PolarHBondContact O-N 3.32Å; F197-V199 PolarHBondContact O-N 3.42Å; V199-P204 WeakPolarHBondContact O-CD 3.32Å
200	N	93.3	Very high	87.6	Confident	113 Å²	113	58.4 Å²	58.4	60%	0.604	30%	0.301	S	S	*	.	I	π-helix	trans	-88.8	-23.3	-173.2	-69.8	-85.2	0	0	0	114.3	M196 P204	M196-N200 WeakPolarHBondContact O-CB 3.43Å; M196-N200 PolarHBondContact O-N 2.7Å; M196-N200 PolarHBondContact O-ND2 2.97Å; N200-P204 WeakPolarHBondContact O-CG 3.19Å
201	V	92.4	Very high	85.9	Confident	46 Å²	46	61.2 Å²	61.2	28%	0.279	31%	0.313	S	S	.	.	I	π-helix	trans	-120.2	-56.4	-176.5	-172.1	0	0	0	0	111.6	F197 P204 L205 T369	F197-V201 HydrophobicContact CD1-CB 4.36Å; F197-V201 HydrophobicContact CD2-CB 4.42Å; F197-V201 HydrophobicContact CD2-CG2 3.92Å; F197-V201 HydrophobicContact CE1-CB 4.15Å; F197-V201 HydrophobicContact CE1-CG1 4.27Å; F197-V201 HydrophobicContact CE2-CB 4.22Å; F197-V201 HydrophobicContact CE2-CG1 4.4Å; F197-V201 HydrophobicContact CE2-CG2 3.84Å; F197-V201 HydrophobicContact CG-CB 4.49Å; F197-V201 HydrophobicContact CG-CG2 4.36Å; F197-V201 HydrophobicContact CZ-CB 4.08Å; F197-V201 HydrophobicContact CZ-CG1 3.97Å; F197-V201 HydrophobicContact CZ-CG2 4.21Å; F197-V201 WeakPolarHBondContact O-CA 3.06Å; F197-V201 WeakPolarHBondContact O-CB 3.46Å; F197-V201 PolarHBondContact O-N 3.41Å; V201-P204 WeakPolarHBondContact O-CD 3.32Å; V201-P204 WeakPolarHBondContact O-CG 3.23Å; V201-L205 WeakPolarHBondContact O-CB 3.36Å; V201-L205 WeakPolarHBondContact O-CD1 3.45Å; V201-L205 PolarHBondContact O-N 3.31Å; V201-T369 HydrophobicContact CG1-CG2 3.78Å
202	I	91.7	Very high	84	Confident	0 Å²	0	62.2 Å²	62.2	0%	0	34%	0.335	C	S	.	.	I	π-helix	trans	-68.1	-46	-172.7	-58.4	179.3	0	0	0	111.3	L164 I167 F197 S198 L205 S206 V372 L406	L164-I202 HydrophobicContact CD2-CD1 3.54Å; I167-I202 HydrophobicContact CD1-CD1 3.94Å; F197-I202 HydrophobicContact CD1-CD1 4.05Å; F197-I202 HydrophobicContact CD1-CG1 4.03Å; F197-I202 HydrophobicContact CE1-CD1 4.25Å; F197-I202 HydrophobicContact CE1-CG1 4.03Å; F197-I202 PolarHBondContact O-N 3.1Å; S198-I202 PolarHBondContact O-N 2.9Å; I202-L205 PolarHBondContact O-N 2.54Å; I202-S206 WeakPolarHBondContact O-CB 3.36Å; I202-S206 PolarHBondContact O-N 2.86Å; I202-S206 PolarHBondContact O-OG 3.11Å; I202-V372 HydrophobicContact CG2-CB 4.12Å; I202-V372 HydrophobicContact CG2-CG1 3.47Å; I202-V372 VanDerWaalsContact CG2-CG1 3.47Å; I202-L406 HydrophobicContact CG2-CD1 3.94Å; I202-L406 HydrophobicContact CG2-CD2 4.3Å
203	L	90.9	Very high	82.5	Confident	31 Å²	31	63.7 Å²	63.7	16%	0.162	34%	0.341	C	S	.	.	H	α-helix	trans	-58.8	-53.3	-178.8	-178.6	61.2	0	0	0	113.2	S198 L205 S206 L207 T402 L403 L406	S198-L203 WeakPolarHBondContact O-CB 3.23Å; S198-L203 PolarHBondContact O-N 3.41Å; L203-L205 PolarHBondContact O-N 3.27Å; L203-S206 PolarHBondContact O-N 2.87Å; L203-S206 VanDerWaalsContact O-N 3.16Å; L203-L207 HydrophobicContact CD1-CD1 3.94Å; L203-L207 HydrophobicContact CD1-CG 4.26Å; L203-L207 HydrophobicContact CG-CD1 4.11Å; L203-L207 WeakPolarHBondContact O-CG 3.19Å; L203-L207 PolarHBondContact O-N 2.88Å; L203-T402 HydrophobicContact CD1-CG2 4.19Å; L203-L403 HydrophobicContact CD2-CD1 4.41Å; L203-L406 HydrophobicContact CB-CD2 3.78Å; L203-L406 HydrophobicContact CD1-CD2 4.14Å
204	P	90	Very high	80.8	Confident	60 Å²	60	65 Å²	65	39%	0.39	35%	0.347	S	S	.	.	H	α-helix	trans	-63.2	-40.1	178.1	21.8	-31.6	0	0	0	112.7	V199 N200 V201 S206 L207	V199-P204 WeakPolarHBondContact O-CD 3.32Å; N200-P204 WeakPolarHBondContact O-CG 3.19Å; V201-P204 WeakPolarHBondContact O-CD 3.32Å; V201-P204 WeakPolarHBondContact O-CG 3.23Å; P204-S206 VanDerWaalsContact C-N 3.27Å; P204-S206 PolarHBondContact O-N 3.49Å; P204-L207 PolarHBondContact O-N 2.83Å
205	L	86.8	Confident	79.4	Confident	58 Å²	58	65.6 Å²	65.6	30%	0.304	35%	0.354	S	S	.	.	H	α-helix	trans	-60.7	-36.8	173.8	-95	62.4	0	0	0	112.2	V201 I202 L203 L207 L208 T369 P373	V201-L205 WeakPolarHBondContact O-CB 3.36Å; V201-L205 WeakPolarHBondContact O-CD1 3.45Å; V201-L205 PolarHBondContact O-N 3.31Å; I202-L205 PolarHBondContact O-N 2.54Å; L203-L205 PolarHBondContact O-N 3.27Å; L205-L207 VanDerWaalsContact C-N 3.31Å; L205-L207 PolarHBondContact O-N 3.04Å; L205-L208 PolarHBondContact O-N 3.25Å; L205-T369 HydrophobicContact CD2-CG2 4.4Å; L205-P373 HydrophobicContact CB-CG 4.06Å
206	S	84.6	Confident	78.4	Confident	10 Å²	10	70.6 Å²	70.6	7%	0.07	37%	0.369	C	S	.	.	H	α-helix	trans	-76.8	-12.7	-178.2	-60.7	0	0	0	0	114.5	I202 L203 P204 L376	I202-S206 WeakPolarHBondContact O-CB 3.36Å; I202-S206 PolarHBondContact O-N 2.86Å; I202-S206 PolarHBondContact O-OG 3.11Å; L203-S206 PolarHBondContact O-N 2.87Å; L203-S206 VanDerWaalsContact O-N 3.16Å; P204-S206 VanDerWaalsContact C-N 3.27Å; P204-S206 PolarHBondContact O-N 3.49Å; S206-L376 VanDerWaalsContact CB-CD1 3.47Å; S206-L376 VanDerWaalsContact OG-CD1 3.28Å; S206-L376 WeakPolarHBondContact OG-CD1 3.33Å
207	L	84.1	Confident	77.7	Confident	54 Å²	54	68.4 Å²	68.4	28%	0.283	36%	0.361	S	S	.	.	T	Hydrogen-bonded Turn	trans	-97.9	0.3	177.5	-67.3	170.2	0	0	0	112.8	L203 P204 L205 K209 A399 T402	L203-L207 HydrophobicContact CD1-CD1 3.94Å; L203-L207 HydrophobicContact CD1-CG 4.26Å; L203-L207 HydrophobicContact CG-CD1 4.11Å; L203-L207 WeakPolarHBondContact O-CG 3.19Å; L203-L207 PolarHBondContact O-N 2.88Å; P204-L207 PolarHBondContact O-N 2.83Å; L205-L207 VanDerWaalsContact C-N 3.31Å; L205-L207 PolarHBondContact O-N 3.04Å; L207-K209 PolarHBondContact O-N 3.42Å; L207-A399 HydrophobicContact CD2-CB 3.93Å; L207-T402 HydrophobicContact CD2-CG2 4.22Å
208	L	78.6	Confident	77.1	Confident	114 Å²	114	66.8 Å²	66.8	60%	0.597	35%	0.354	S	S	*	.			trans	-72.9	113.7	178.7	-64.4	177.7	0	0	0	111.3	L205 N210	L205-L208 PolarHBondContact O-N 3.25Å; L208-N210 VanDerWaalsContact C-N 3.25Å; L208-N210 PolarHBondContact O-N 3.05Å
209	K	59.5	Low	76.7	Confident	137 Å²	137	68.2 Å²	68.2	60%	0.596	37%	0.37	S	S	*	.	S	Bend	trans	-56.5	-34.5	-177.4	-154.8	-164.3	-175.1	-171.9	0	114.5	L207 W395	L207-K209 PolarHBondContact O-N 3.42Å; K209-W395 HydrophobicContact CB-CH2 3.66Å; K209-W395 HydrophobicContact CB-CZ2 3.82Å; K209-W395 HydrophobicContact CD-CZ2 3.84Å; K209-W395 HydrophobicContact CG-CH2 3.95Å; K209-W395 HydrophobicContact CG-CZ2 3.75Å
210	N	56.1	Low	76.4	Confident	113 Å²	113	68.5 Å²	68.5	60%	0.604	37%	0.368	S	S	*	.			trans	-108	88.8	-160.5	-68.9	-6.2	0	0	0	111.5	L208 G212	L208-N210 VanDerWaalsContact C-N 3.25Å; L208-N210 PolarHBondContact O-N 3.05Å; N210-G212 PolarHBondContact O-N 3.4Å
211	L	54.5	Low	76.2	Confident	68 Å²	68	63.2 Å²	63.2	36%	0.356	34%	0.34	S	S	.	.	G	3₁₀ helix	trans	-67.8	9.8	173.6	-58.6	178.7	0	0	0	114.1	Y213 L214 F377	L211-Y213 PolarHBondContact O-N 3.14Å; L211-L214 HydrophobicContact CB-CB 4.27Å; L211-L214 HydrophobicContact CB-CD2 4.26Å; L211-L214 HydrophobicContact CD1-CD2 4.44Å; L211-L214 HydrophobicContact CD2-CD1 4.18Å; L211-L214 HydrophobicContact CD2-CD2 4.23Å; L211-L214 WeakPolarHBondContact O-CB 3.32Å; L211-L214 PolarHBondContact O-N 3.03Å; L211-F377 HydrophobicContact CD1-CB 4.31Å; L211-F377 HydrophobicContact CD1-CD2 3.87Å; L211-F377 HydrophobicContact CD1-CG 4.2Å
212	G	53.9	Low	76	Confident	69 Å²	69	62.1 Å²	62.1	71%	0.711	33%	0.332	S	S	*	.	G	3₁₀ helix	trans	-61.2	-24.5	176	0	0	0	0	0	114.2	N210 L214	N210-G212 PolarHBondContact O-N 3.4Å; G212-L214 VanDerWaalsContact C-N 3.34Å
213	Y	59.9	Low	76	Confident	177 Å²	177	67.6 Å²	67.6	69%	0.694	36%	0.361	S	S	*	.	G	3₁₀ helix	trans	-82.1	-10.3	173.9	-62.3	-78.4	0	0	0	113.7	L211 G215 Y216 T217	L211-Y213 PolarHBondContact O-N 3.14Å; Y213-G215 PolarHBondContact O-N 3.3Å; Y213-Y216 PolarHBondContact O-N 2.99Å; Y213-T217 PolarHBondContact O-N 2.86Å
214	L	57.4	Low	76.1	Confident	30 Å²	30	66.9 Å²	66.9	16%	0.157	36%	0.358	C	S	.	.	H	α-helix	trans	-66.4	-25.5	-169.2	-155.2	73.3	0	0	0	113.1	L211 G212 Y216 T217 S218 V374	L211-L214 HydrophobicContact CB-CB 4.27Å; L211-L214 HydrophobicContact CB-CD2 4.26Å; L211-L214 HydrophobicContact CD1-CD2 4.44Å; L211-L214 HydrophobicContact CD2-CD1 4.18Å; L211-L214 HydrophobicContact CD2-CD2 4.23Å; L211-L214 WeakPolarHBondContact O-CB 3.32Å; L211-L214 PolarHBondContact O-N 3.03Å; G212-L214 VanDerWaalsContact C-N 3.34Å; L214-Y216 VanDerWaalsContact C-N 3.28Å; L214-Y216 PolarHBondContact O-N 2.96Å; L214-T217 WeakPolarHBondContact CA-OG1 3.2Å; L214-T217 PolarHBondContact O-OG1 3.05Å; L214-T217 VanDerWaalsContact O-OG1 3.1Å; L214-S218 WeakPolarHBondContact O-CB 3.32Å; L214-S218 PolarHBondContact O-N 3Å; L214-S218 PolarHBondContact O-OG 2.91Å; L214-V374 HydrophobicContact CD1-CG2 4.04Å; L214-V374 HydrophobicContact CD2-CG1 4.3Å; L214-V374 HydrophobicContact CD2-CG2 4.09Å; L214-V374 HydrophobicContact CG-CG2 4.28Å
215	G	65.6	Low	76.1	Confident	13 Å²	13	64.2 Å²	64.2	13%	0.134	34%	0.341	C	S	.	.	H	α-helix	trans	-65.6	-27.6	172.8	0	0	0	0	0	113.8	Y213 G219	Y213-G215 PolarHBondContact O-N 3.3Å; G215-G219 PolarHBondContact O-N 2.66Å
216	Y	73.3	Confident	76.5	Confident	179 Å²	179	64 Å²	64	70%	0.702	34%	0.342	S	S	*	.	H	α-helix	trans	-82.4	-44.5	175.6	-65.9	-80.1	0	0	0	111.8	Y213 L214 S218 G219 L220	Y213-Y216 PolarHBondContact O-N 2.99Å; L214-Y216 VanDerWaalsContact C-N 3.28Å; L214-Y216 PolarHBondContact O-N 2.96Å; Y216-S218 PolarHBondContact O-N 3.4Å; Y216-G219 PolarHBondContact O-N 3.33Å; Y216-L220 PolarHBondContact O-N 3.47Å
217	T	79.3	Confident	76.9	Confident	41 Å²	41	67 Å²	67	25%	0.252	35%	0.353	S	S	.	.	H	α-helix	trans	-63.4	-30.1	174.3	60.2	0	0	0	0	111.5	Y213 L214 L220 S221 L370	Y213-T217 PolarHBondContact O-N 2.86Å; L214-T217 WeakPolarHBondContact CA-OG1 3.2Å; L214-T217 PolarHBondContact O-OG1 3.05Å; L214-T217 VanDerWaalsContact O-OG1 3.1Å; T217-L220 PolarHBondContact O-N 3.44Å; T217-S221 WeakPolarHBondContact O-CB 3.41Å; T217-S221 PolarHBondContact O-N 3.05Å; T217-L370 HydrophobicContact CG2-CD2 4.01Å
218	S	80.1	Confident	77.4	Confident	7 Å²	7	64.4 Å²	64.4	5%	0.049	34%	0.34	C	S	.	.	H	α-helix	trans	-60	-53.2	171	-71.4	0	0	0	0	112.1	N77 I80 L214 Y216 L220 S221 L222	N77-S218 WeakPolarHBondContact OD1-CB 3.37Å; N77-S218 PolarHBondContact OD1-OG 3.48Å; N77-S218 VanDerWaalsContact OD1-OG 3.12Å; I80-S218 VanDerWaalsContact CD1-C 3.48Å; I80-S218 WeakPolarHBondContact CD1-O 3.47Å; L214-S218 WeakPolarHBondContact O-CB 3.32Å; L214-S218 PolarHBondContact O-N 3Å; L214-S218 PolarHBondContact O-OG 2.91Å; Y216-S218 PolarHBondContact O-N 3.4Å; S218-L220 PolarHBondContact O-N 2.75Å; S218-S221 PolarHBondContact O-N 2.91Å; S218-S221 VanDerWaalsContact O-N 3.1Å; S218-L222 PolarHBondContact O-N 3.48Å
219	G	84.7	Confident	78.2	Confident	32 Å²	32	59.7 Å²	59.7	33%	0.33	32%	0.315	S	S	.	.	H	α-helix	trans	-54.9	-40.3	177.3	0	0	0	0	0	113.1	G215 Y216 L223	G215-G219 PolarHBondContact O-N 2.66Å; Y216-G219 PolarHBondContact O-N 3.33Å; G219-L223 WeakPolarHBondContact O-CB 3.4Å; G219-L223 PolarHBondContact O-N 3.31Å; G219-L223 VanDerWaalsContact O-N 3.09Å
220	L	88.1	Confident	79.9	Confident	87 Å²	87	57.1 Å²	57.1	46%	0.455	31%	0.307	S	S	.	.	H	α-helix	trans	-65.2	-47.8	174.4	179.7	58.8	0	0	0	112.4	Y216 T217 S218 L222 L223 C224 L370	Y216-L220 PolarHBondContact O-N 3.47Å; T217-L220 PolarHBondContact O-N 3.44Å; S218-L220 PolarHBondContact O-N 2.75Å; L220-L222 VanDerWaalsContact C-N 3.28Å; L220-L222 PolarHBondContact O-N 2.88Å; L220-L223 WeakPolarHBondContact O-CB 3.43Å; L220-L223 PolarHBondContact O-N 3.04Å; L220-L223 VanDerWaalsContact O-N 3.15Å; L220-C224 PolarHBondContact O-N 2.8Å; L220-C224 PolarHBondContact O-SG 3Å; L220-C224 VanDerWaalsContact O-SG 3.33Å; L220-L370 HydrophobicContact CD2-CD1 3.9Å; L220-L370 HydrophobicContact CG-CD1 4.31Å
221	S	88.4	Confident	81.7	Confident	2 Å²	2	51.8 Å²	51.8	1%	0.014	28%	0.279	C	S	.	.	H	α-helix	trans	-60.4	-36.6	179.1	-172.1	0	0	0	0	112.7	T217 S218 M225 A367 T371	T217-S221 WeakPolarHBondContact O-CB 3.41Å; T217-S221 PolarHBondContact O-N 3.05Å; S218-S221 PolarHBondContact O-N 2.91Å; S218-S221 VanDerWaalsContact O-N 3.1Å; S221-M225 WeakPolarHBondContact O-CG 3.43Å; S221-M225 PolarHBondContact O-N 2.85Å; S221-A367 WeakPolarHBondContact OG-CB 3.36Å; S221-A367 PolarHBondContact OG-O 3.32Å; S221-T371 PolarHBondContact OG-OG1 2.95Å
222	L	88.4	Confident	83.6	Confident	23 Å²	23	48.6 Å²	48.6	12%	0.12	26%	0.262	C	S	.	.	H	α-helix	trans	-70.5	-41.6	174.8	-176.6	61.6	0	0	0	111.8	F76 I80 M83 S218 L220 C224 M225 V226 M320 M323	F76-L222 HydrophobicContact CD1-CD2 3.56Å; F76-L222 HydrophobicContact CE1-CD2 4.01Å; I80-L222 HydrophobicContact CD1-CB 4.49Å; I80-L222 HydrophobicContact CG1-CB 4.37Å; M83-L222 HydrophobicContact CE-CD1 3.91Å; M83-L222 HydrophobicContact SD-CD1 3.77Å; S218-L222 PolarHBondContact O-N 3.48Å; L220-L222 VanDerWaalsContact C-N 3.28Å; L220-L222 PolarHBondContact O-N 2.88Å; L222-C224 VanDerWaalsContact C-N 3.32Å; L222-C224 PolarHBondContact O-N 2.96Å; L222-M225 PolarHBondContact O-N 3.29Å; L222-V226 WeakPolarHBondContact O-CG2 3.34Å; L222-V226 PolarHBondContact O-N 3.18Å; L222-M320 HydrophobicContact CD1-CE 4.11Å; L222-M323 HydrophobicContact CD1-CE 4.47Å; L222-M323 HydrophobicContact CD1-SD 4.23Å
223	L	92	Very high	85.5	Confident	115 Å²	115	47.4 Å²	47.4	60%	0.602	24%	0.239	S	C	*	.	H	α-helix	trans	-58.9	-43.3	176.3	-178	64.2	0	0	0	111.8	G219 L220 M225 V226 F227	G219-L223 WeakPolarHBondContact O-CB 3.4Å; G219-L223 PolarHBondContact O-N 3.31Å; G219-L223 VanDerWaalsContact O-N 3.09Å; L220-L223 WeakPolarHBondContact O-CB 3.43Å; L220-L223 PolarHBondContact O-N 3.04Å; L220-L223 VanDerWaalsContact O-N 3.15Å; L223-M225 VanDerWaalsContact C-N 3.32Å; L223-M225 PolarHBondContact O-N 3.42Å; L223-V226 PolarHBondContact O-N 2.66Å; L223-F227 PolarHBondContact O-N 2.83Å
224	C	92.3	Very high	87.1	Confident	16 Å²	16	42.1 Å²	42.1	11%	0.108	22%	0.222	C	C	.	.	H	α-helix	trans	-59.2	-39.5	175.4	-69.9	0	0	0	0	113.1	L220 L222 F227 F228 A363 A367	L220-C224 PolarHBondContact O-N 2.8Å; L220-C224 PolarHBondContact O-SG 3Å; L220-C224 VanDerWaalsContact O-SG 3.33Å; L222-C224 VanDerWaalsContact C-N 3.32Å; L222-C224 PolarHBondContact O-N 2.96Å; C224-F227 PolarHBondContact O-N 2.86Å; C224-F228 PolarHBondContact O-N 2.86Å; C224-A363 HydrophobicContact CB-CB 3.92Å; C224-A363 WeakPolarHBondContact CB-O 3.34Å; C224-A367 HydrophobicContact CB-CB 3.93Å
225	M	91.3	Very high	88.6	Confident	4 Å²	4	41.1 Å²	41.1	2%	0.02	22%	0.216	C	C	.	.	H	α-helix	trans	-78.8	-28.1	179	-67.7	-65.8	-164.9	0	0	113.3	M83 S221 L222 L223 L229 M323 V364 A367 V368	M83-M225 HydrophobicContact CE-CB 3.8Å; M83-M225 HydrophobicContact CE-CG 3.57Å; M83-M225 HydrophobicContact CG-CB 4.48Å; M83-M225 HydrophobicContact CG-CG 4.39Å; M83-M225 HydrophobicContact SD-CB 3.29Å; M83-M225 WeakPolarHBondContact SD-CB 3.25Å; M83-M225 HydrophobicContact SD-CG 3.59Å; M83-M225 VanDerWaalsContact SD-CG 3.59Å; S221-M225 WeakPolarHBondContact O-CG 3.43Å; S221-M225 PolarHBondContact O-N 2.85Å; L222-M225 PolarHBondContact O-N 3.29Å; L223-M225 VanDerWaalsContact C-N 3.32Å; L223-M225 PolarHBondContact O-N 3.42Å; M225-L229 PolarHBondContact O-N 3.37Å; M225-M323 HydrophobicContact CB-CE 4.22Å; M225-V364 HydrophobicContact CE-CG1 4.4Å; M225-V364 HydrophobicContact SD-CG2 4.29Å; M225-A367 HydrophobicContact CE-CB 4.09Å; M225-A367 HydrophobicContact CG-CB 4.43Å; M225-V368 HydrophobicContact CE-CG1 4.36Å
226	V	93.7	Very high	89.8	Confident	53 Å²	53	42.6 Å²	42.6	32%	0.321	22%	0.219	S	C	.	.	H	α-helix	trans	-66.7	-38.5	167	171.8	0	0	0	0	110.7	L222 L223 L229 I230 M323	L222-V226 WeakPolarHBondContact O-CG2 3.34Å; L222-V226 PolarHBondContact O-N 3.18Å; L223-V226 PolarHBondContact O-N 2.66Å; V226-L229 PolarHBondContact O-N 3.41Å; V226-I230 HydrophobicContact CG1-CD1 4.01Å; V226-I230 WeakPolarHBondContact O-CG1 3.42Å; V226-I230 PolarHBondContact O-N 3.31Å; V226-M323 HydrophobicContact CG2-CE 3.96Å; V226-M323 HydrophobicContact CG2-SD 4.08Å
227	F	94.5	Very high	90.6	Very high	72 Å²	72	41.7 Å²	41.7	32%	0.316	22%	0.219	S	C	.	.	H	α-helix	trans	-64.9	-41.6	173.7	176.3	-128.2	0	0	0	112.5	L223 C224 L229 I230 M231 L356 A359 V360 A363	L223-F227 PolarHBondContact O-N 2.83Å; C224-F227 PolarHBondContact O-N 2.86Å; F227-L229 PolarHBondContact O-N 3.46Å; F227-I230 PolarHBondContact O-N 3.43Å; F227-M231 PolarHBondContact O-N 3.19Å; F227-L356 HydrophobicContact CE2-CD1 4Å; F227-L356 HydrophobicContact CZ-CD1 3.88Å; F227-A359 HydrophobicContact CE1-CB 4.21Å; F227-A359 HydrophobicContact CZ-CB 4.23Å; F227-V360 HydrophobicContact CD1-CG2 3.76Å; F227-V360 HydrophobicContact CE1-CB 4.37Å; F227-V360 HydrophobicContact CE1-CG2 3.42Å; F227-V360 VanDerWaalsContact CE1-CG2 3.42Å; F227-V360 HydrophobicContact CE2-CG2 4.31Å; F227-V360 HydrophobicContact CG-CG2 4.35Å; F227-V360 HydrophobicContact CZ-CG2 3.72Å; F227-A363 HydrophobicContact CD1-CB 3.91Å; F227-A363 HydrophobicContact CE1-CB 4.4Å
228	F	93.8	Very high	90.9	Very high	0 Å²	0	45.1 Å²	45.1	0%	0	23%	0.232	C	C	.	.	H	α-helix	trans	-55	-49	168.8	164.7	-97.4	0	0	0	111.9	I87 L88 C224 I230 M231 V232 A327 L343 L344 V360 V364	I87-F228 HydrophobicContact CD1-CD1 4.3Å; I87-F228 HydrophobicContact CD1-CE1 4.11Å; I87-F228 HydrophobicContact CG1-CE1 4.2Å; L88-F228 HydrophobicContact CD2-CE1 4.05Å; L88-F228 HydrophobicContact CD2-CE2 3.68Å; L88-F228 HydrophobicContact CD2-CZ 3.41Å; L88-F228 VanDerWaalsContact CD2-CZ 3.41Å; C224-F228 PolarHBondContact O-N 2.86Å; F228-I230 PolarHBondContact O-N 3.37Å; F228-M231 PolarHBondContact O-N 3.5Å; F228-V232 HydrophobicContact CD2-CG2 4.28Å; F228-V232 HydrophobicContact CE1-CG2 4.16Å; F228-V232 HydrophobicContact CE2-CG2 3.87Å; F228-V232 HydrophobicContact CZ-CG2 3.81Å; F228-V232 WeakPolarHBondContact O-CG2 3.16Å; F228-V232 PolarHBondContact O-N 2.98Å; F228-A327 HydrophobicContact CE1-CB 4.49Å; F228-L343 HydrophobicContact CZ-CD2 4.13Å; F228-L344 HydrophobicContact CD2-CD1 4.39Å; F228-L344 HydrophobicContact CE2-CD1 4.24Å; F228-V360 HydrophobicContact CB-CG1 3.97Å; F228-V360 HydrophobicContact CD2-CG1 3.73Å; F228-V360 HydrophobicContact CG-CG1 4.35Å; F228-V364 HydrophobicContact CB-CG2 4.08Å; F228-V364 HydrophobicContact CD2-CG2 4.04Å; F228-V364 HydrophobicContact CG-CG2 4.26Å
229	L	95.1	Very high	91.1	Very high	15 Å²	15	45.1 Å²	45.1	8%	0.079	23%	0.231	C	C	.	.	H	α-helix	trans	-59.3	-44.5	177.5	172.7	61.1	0	0	0	112.5	M225 V226 F227 M231 V232 I233 M323 L326 A327	M225-L229 PolarHBondContact O-N 3.37Å; V226-L229 PolarHBondContact O-N 3.41Å; F227-L229 PolarHBondContact O-N 3.46Å; L229-M231 VanDerWaalsContact C-N 3.31Å; L229-M231 PolarHBondContact O-N 3.46Å; L229-V232 PolarHBondContact O-N 2.96Å; L229-I233 HydrophobicContact CD1-CD1 4Å; L229-I233 HydrophobicContact CD1-CG1 4.3Å; L229-I233 HydrophobicContact CG-CD1 4.07Å; L229-I233 WeakPolarHBondContact O-CG1 3.31Å; L229-I233 PolarHBondContact O-N 3.21Å; L229-M323 HydrophobicContact CD2-CB 4.2Å; L229-M323 HydrophobicContact CD2-CG 3.91Å; L229-L326 HydrophobicContact CD1-CB 3.69Å; L229-L326 HydrophobicContact CD2-CB 4.48Å; L229-L326 HydrophobicContact CD2-CD1 4.46Å; L229-A327 HydrophobicContact CD1-CB 4.02Å
230	I	95.2	Very high	90.8	Very high	84 Å²	84	47.2 Å²	47.2	43%	0.431	24%	0.24	S	C	.	.	H	α-helix	trans	-59.7	-42.6	176.7	-70.7	164.5	0	0	0	110.7	V226 F227 F228 I233 I234	V226-I230 HydrophobicContact CG1-CD1 4.01Å; V226-I230 WeakPolarHBondContact O-CG1 3.42Å; V226-I230 PolarHBondContact O-N 3.31Å; F227-I230 PolarHBondContact O-N 3.43Å; F228-I230 PolarHBondContact O-N 3.37Å; I230-I233 PolarHBondContact O-N 3.29Å; I230-I234 HydrophobicContact CG2-CD1 3.75Å; I230-I234 HydrophobicContact CG2-CG1 4.49Å; I230-I234 VanDerWaalsContact O-CG1 3.3Å; I230-I234 WeakPolarHBondContact O-CG1 3.19Å; I230-I234 PolarHBondContact O-N 3.16Å
231	M	93.8	Very high	90.2	Very high	1 Å²	1	45.5 Å²	45.5	1%	0.005	23%	0.234	C	C	.	.	H	α-helix	trans	-65.1	-43.3	176.8	176.2	-81.5	-165.4	0	0	112.4	F227 F228 L229 I233 I234 K235 Y347 L356 L357 V360	F227-M231 PolarHBondContact O-N 3.19Å; F228-M231 PolarHBondContact O-N 3.5Å; L229-M231 VanDerWaalsContact C-N 3.31Å; L229-M231 PolarHBondContact O-N 3.46Å; M231-I233 VanDerWaalsContact C-N 3.28Å; M231-I233 PolarHBondContact O-N 3.19Å; M231-I234 PolarHBondContact O-N 2.96Å; M231-I234 VanDerWaalsContact O-N 3.15Å; M231-K235 HydrophobicContact CE-CD 4.29Å; M231-K235 HydrophobicContact CE-CG 3.57Å; M231-K235 HydrophobicContact CG-CG 4.2Å; M231-K235 WeakPolarHBondContact O-CB 3.49Å; M231-K235 WeakPolarHBondContact O-CG 3.38Å; M231-K235 PolarHBondContact O-N 3.45Å; M231-K235 HydrophobicContact SD-CG 3.71Å; M231-Y347 HydrophobicContact CE-CD1 4.36Å; M231-Y347 HydrophobicContact CE-CG 4.35Å; M231-L356 HydrophobicContact CG-CD2 4.15Å; M231-L356 HydrophobicContact CG-CG 3.93Å; M231-L357 HydrophobicContact CE-CB 3.81Å; M231-L357 HydrophobicContact CE-CD1 3.47Å; M231-L357 VanDerWaalsContact CE-CD1 3.47Å; M231-L357 HydrophobicContact CE-CG 4.2Å; M231-V360 HydrophobicContact CB-CG2 3.62Å; M231-V360 HydrophobicContact CG-CB 4.48Å; M231-V360 HydrophobicContact CG-CG2 3.78Å
232	V	94.1	Very high	89.5	Confident	0 Å²	0	49.8 Å²	49.8	0%	0	26%	0.262	C	S	.	.	H	α-helix	trans	-59.4	-41.3	177.1	171.3	0	0	0	0	110.9	F228 L229 K236 F330 L343 Y347	F228-V232 HydrophobicContact CD2-CG2 4.28Å; F228-V232 HydrophobicContact CE1-CG2 4.16Å; F228-V232 HydrophobicContact CE2-CG2 3.87Å; F228-V232 HydrophobicContact CZ-CG2 3.81Å; F228-V232 WeakPolarHBondContact O-CG2 3.16Å; F228-V232 PolarHBondContact O-N 2.98Å; L229-V232 PolarHBondContact O-N 2.96Å; V232-K236 PolarHBondContact O-N 3.49Å; V232-F330 HydrophobicContact CG1-CB 3.85Å; V232-L343 HydrophobicContact CG1-CD2 4.4Å; V232-L343 HydrophobicContact CG2-CD2 4.17Å; V232-Y347 HydrophobicContact CG2-CE2 4.12Å
233	I	95	Very high	89	Confident	45 Å²	45	50.2 Å²	50.2	23%	0.231	26%	0.264	C	S	.	.	H	α-helix	trans	-63.2	-48.8	173.7	-65	164.7	0	0	0	110.9	L229 I230 M231 K235 K236 F237 F330	L229-I233 HydrophobicContact CD1-CD1 4Å; L229-I233 HydrophobicContact CD1-CG1 4.3Å; L229-I233 HydrophobicContact CG-CD1 4.07Å; L229-I233 WeakPolarHBondContact O-CG1 3.31Å; L229-I233 PolarHBondContact O-N 3.21Å; I230-I233 PolarHBondContact O-N 3.29Å; M231-I233 VanDerWaalsContact C-N 3.28Å; M231-I233 PolarHBondContact O-N 3.19Å; I233-K235 PolarHBondContact O-N 3.44Å; I233-K236 PolarHBondContact O-N 3.35Å; I233-F237 HydrophobicContact CG2-CE2 4.09Å; I233-F237 WeakPolarHBondContact O-CD2 3.28Å; I233-F330 HydrophobicContact CB-CD1 4.35Å; I233-F330 HydrophobicContact CB-CG 4.4Å; I233-F330 HydrophobicContact CG1-CB 4.26Å; I233-F330 HydrophobicContact CG1-CD1 4.23Å; I233-F330 HydrophobicContact CG1-CD2 3.79Å; I233-F330 HydrophobicContact CG1-CE2 4.18Å; I233-F330 HydrophobicContact CG1-CG 3.83Å; I233-F330 HydrophobicContact CG2-CD1 4.24Å; I233-F330 HydrophobicContact CG2-CE1 4.09Å; I233-F330 HydrophobicContact CG2-CZ 4.38Å
234	I	92.4	Very high	87.9	Confident	65 Å²	65	47.4 Å²	47.4	33%	0.333	25%	0.253	S	S	.	.	H	α-helix	trans	-59.8	-46	178.9	-71.9	167.3	0	0	0	111.2	I230 M231 K236 F237 Q238 L356	I230-I234 HydrophobicContact CG2-CD1 3.75Å; I230-I234 HydrophobicContact CG2-CG1 4.49Å; I230-I234 VanDerWaalsContact O-CG1 3.3Å; I230-I234 WeakPolarHBondContact O-CG1 3.19Å; I230-I234 PolarHBondContact O-N 3.16Å; M231-I234 PolarHBondContact O-N 2.96Å; M231-I234 VanDerWaalsContact O-N 3.15Å; I234-K236 VanDerWaalsContact C-N 3.3Å; I234-K236 PolarHBondContact O-N 3.25Å; I234-F237 PolarHBondContact O-N 2.91Å; I234-F237 VanDerWaalsContact O-N 3.07Å; I234-Q238 HydrophobicContact CG2-CG 4.17Å; I234-Q238 PolarHBondContact O-N 3.31Å; I234-L356 HydrophobicContact CG2-CD2 4.26Å
235	K	89.9	Confident	86.6	Confident	10 Å²	10	53.7 Å²	53.7	4%	0.043	28%	0.284	C	S	.	.	H	α-helix	trans	-65.8	-30.2	-177.4	-70.9	-62.9	173.6	-162	0	113	M231 I233 F237 Q238 I239 Y347 D354	M231-K235 HydrophobicContact CE-CD 4.29Å; M231-K235 HydrophobicContact CE-CG 3.57Å; M231-K235 HydrophobicContact CG-CG 4.2Å; M231-K235 WeakPolarHBondContact O-CB 3.49Å; M231-K235 WeakPolarHBondContact O-CG 3.38Å; M231-K235 PolarHBondContact O-N 3.45Å; M231-K235 HydrophobicContact SD-CG 3.71Å; I233-K235 PolarHBondContact O-N 3.44Å; K235-F237 PolarHBondContact O-N 3.45Å; K235-Q238 PolarHBondContact O-N 2.82Å; K235-Q238 VanDerWaalsContact O-N 3.13Å; K235-I239 HydrophobicContact CB-CD1 4.02Å; K235-I239 HydrophobicContact CB-CG1 4.48Å; K235-I239 HydrophobicContact CD-CD1 4.44Å; K235-I239 WeakPolarHBondContact O-CB 3.37Å; K235-I239 WeakPolarHBondContact O-CG1 3.31Å; K235-I239 PolarHBondContact O-N 2.88Å; K235-Y347 HydrophobicContact CB-CD1 4.45Å; K235-Y347 HydrophobicContact CB-CE1 3.57Å; K235-Y347 HydrophobicContact CG-CD1 4.45Å; K235-Y347 HydrophobicContact CG-CE1 3.99Å; K235-D354 IonicContact NZ-OD1 3.01Å; K235-D354 PolarHBondContact NZ-OD1 3.02Å; K235-D354 IonicContact NZ-OD2 2.59Å; K235-D354 PolarHBondContact NZ-OD2 3.23Å
236	K	90.3	Very high	84.7	Confident	43 Å²	43	58 Å²	58	19%	0.187	31%	0.313	C	S	.	.	H	α-helix	trans	-56.8	-34.8	171.9	174.6	61.1	-137.7	112.2	0	113	V232 I233 I234 F330 L333 T334	V232-K236 PolarHBondContact O-N 3.49Å; I233-K236 PolarHBondContact O-N 3.35Å; I234-K236 VanDerWaalsContact C-N 3.3Å; I234-K236 PolarHBondContact O-N 3.25Å; K236-F330 HydrophobicContact CB-CD1 3.8Å; K236-F330 HydrophobicContact CG-CD1 3.89Å; K236-F330 HydrophobicContact CG-CE1 4.48Å; K236-L333 HydrophobicContact CD-CB 3.67Å; K236-L333 WeakPolarHBondContact CD-O 3.43Å; K236-L333 WeakPolarHBondContact CE-O 3.45Å; K236-L333 PolarHBondContact NZ-O 2.65Å; K236-T334 WeakPolarHBondContact CA-OG1 3.38Å
237	F	89.9	Confident	82.7	Confident	160 Å²	160	59 Å²	59	70%	0.702	33%	0.333	S	S	*	.	H	α-helix	trans	-89.8	-15.3	179.2	-61.7	-71.8	0	0	0	113.6	I233 I234 K235 F330	I233-F237 HydrophobicContact CG2-CE2 4.09Å; I233-F237 WeakPolarHBondContact O-CD2 3.28Å; I234-F237 PolarHBondContact O-N 2.91Å; I234-F237 VanDerWaalsContact O-N 3.07Å; K235-F237 PolarHBondContact O-N 3.45Å; F237-F330 AromaticContact CE2-CE1 3.9Å; F237-F330 HydrophobicContact CE2-CE1 3.9Å; F237-F330 HydrophobicContact CZ-CE1 4.01Å
238	Q	87.1	Confident	80.1	Confident	113 Å²	113	61.3 Å²	61.3	53%	0.528	35%	0.349	S	S	.	.	H	α-helix	trans	-92.9	-32.6	176.1	-68.6	-176.4	-23.6	0	0	113.2	I234 K235 P240	I234-Q238 HydrophobicContact CG2-CG 4.17Å; I234-Q238 PolarHBondContact O-N 3.31Å; K235-Q238 PolarHBondContact O-N 2.82Å; K235-Q238 VanDerWaalsContact O-N 3.13Å; Q238-P240 WeakPolarHBondContact O-CD 3.44Å
239	I	83.3	Confident	77.9	Confident	7 Å²	7	71.1 Å²	71.1	4%	0.036	40%	0.395	C	S	.	.	S	Bend	trans	-88.2	117.6	-177.3	-63.5	175.2	0	0	0	108.9	K235 L243 T334 Y347 Y351	K235-I239 HydrophobicContact CB-CD1 4.02Å; K235-I239 HydrophobicContact CB-CG1 4.48Å; K235-I239 HydrophobicContact CD-CD1 4.44Å; K235-I239 WeakPolarHBondContact O-CB 3.37Å; K235-I239 WeakPolarHBondContact O-CG1 3.31Å; K235-I239 PolarHBondContact O-N 2.88Å; I239-L243 HydrophobicContact CG2-CD2 3.8Å; I239-T334 HydrophobicContact CB-CG2 4.25Å; I239-T334 HydrophobicContact CD1-CG2 3.72Å; I239-T334 HydrophobicContact CG2-CG2 4.29Å; I239-Y347 HydrophobicContact CD1-CD1 3.95Å; I239-Y347 HydrophobicContact CD1-CE1 3.74Å; I239-Y351 HydrophobicContact CB-CE2 4.39Å; I239-Y351 HydrophobicContact CD1-CD2 3.86Å; I239-Y351 HydrophobicContact CD1-CE2 3.54Å; I239-Y351 HydrophobicContact CG1-CD2 4.27Å; I239-Y351 HydrophobicContact CG1-CE2 3.58Å; I239-Y351 HydrophobicContact CG2-CE2 4Å
240	P	77.9	Confident	75.5	Confident	77 Å²	77	74.4 Å²	74.4	50%	0.5	42%	0.416	S	S	.	.			trans	-72	157.7	174.5	32.1	-35.1	0	0	0	111.1	Q238	Q238-P240 WeakPolarHBondContact O-CD 3.44Å
241	C	75.9	Confident	73	Confident	51 Å²	51	77.9 Å²	77.9	35%	0.345	44%	0.435	S	S	.	.	S	Bend	trans	-116.6	133.8	165	-60.4	0	0	0	0	107.3	C266	C241-C266 HydrophobicContact CB-CB 4.28Å
242	P	74.4	Confident	70.7	Confident	91 Å²	91	85.8 Å²	85.8	59%	0.591	48%	0.476	S	S	*	.	S	Bend	cis	-65	157.6	0.2	28.8	-36.5	0	0	0	113.8
243	L	77.9	Confident	68.1	Low	33 Å²	33	90.4 Å²	90.4	17%	0.173	50%	0.504	C	S	.	.	P	Polyproline II helix	trans	-69.6	141.5	-178	-69.3	163.5	0	0	0	110.9	I239 L245 F335 H338 Y350	I239-L243 HydrophobicContact CG2-CD2 3.8Å; L243-L245 PolarHBondContact O-N 3.36Å; L243-F335 HydrophobicContact CD1-CD1 3.99Å; L243-F335 HydrophobicContact CD2-CD1 3.83Å; L243-F335 HydrophobicContact CD2-CE1 4.18Å; L243-H338 HydrophobicContact CD1-CB 4.09Å; L243-Y350 HydrophobicContact CB-CD1 4.31Å; L243-Y350 HydrophobicContact CB-CE1 3.94Å; L243-Y350 HydrophobicContact CD1-CE1 4.09Å; L243-Y350 HydrophobicContact CD1-CE2 4.37Å; L243-Y350 HydrophobicContact CG-CE1 4.47Å
244	P	68.6	Low	65.7	Low	55 Å²	55	94.4 Å²	94.4	36%	0.357	53%	0.533	S	S	.	.	P	Polyproline II helix	trans	-64.7	136.7	176.1	27.4	-34.3	0	0	0	111.3	Y351	P244-Y351 WeakPolarHBondContact CG-OH 3.12Å
245	L	63.8	Low	63	Low	148 Å²	148	99.3 Å²	99.3	78%	0.775	55%	0.554	S	S	*	*	P	Polyproline II helix	trans	-68.4	126.6	175.6	-71.5	171	0	0	0	110.2	L243 G247	L243-L245 PolarHBondContact O-N 3.36Å; L245-G247 PolarHBondContact O-N 2.87Å
246	P	53.1	Low	61	Low	95 Å²	95	103.8 Å²	103.8	62%	0.617	59%	0.587	S	S	*	*	T	Hydrogen-bonded Turn	trans	-72.3	93.2	-178.6	29.2	-34.5	0	0	0	110.8
247	G	50.8	Low	58.4	Low	73 Å²	73	108.8 Å²	108.8	75%	0.753	62%	0.616	S	S	*	*	T	Hydrogen-bonded Turn	trans	149.8	-15.4	170.9	0	0	0	0	0	116.9	L245	L245-G247 PolarHBondContact O-N 2.87Å
248	N	40.6	Very low	56.3	Low	122 Å²	122	108.7 Å²	108.7	65%	0.652	62%	0.622	S	S	*	*			trans	-118.7	86.4	-174.2	-112.7	26.5	0	0	0	113	T250	N248-T250 PolarHBondContact ND2-OG1 3.19Å; N248-T250 VanDerWaalsContact ND2-OG1 3.16Å; N248-T250 PolarHBondContact O-N 2.94Å
249	E	46.7	Very low	54.1	Low	206 Å²	206	108 Å²	108	96%	0.963	63%	0.626	S	S	*	*			trans	-74.9	64.1	159.9	-70.1	-162.4	146.3	0	0	110.5
250	T	43.9	Very low	52.2	Low	83 Å²	83	114.2 Å²	114.2	51%	0.509	66%	0.664	S	S	.	*			trans	-131.9	97.8	179.3	58.2	0	0	0	0	111	N248 I252	N248-T250 PolarHBondContact ND2-OG1 3.19Å; N248-T250 VanDerWaalsContact ND2-OG1 3.16Å; N248-T250 PolarHBondContact O-N 2.94Å; T250-I252 PolarHBondContact O-N 2.91Å
251	N	44.3	Very low	50.7	Low	157 Å²	157	115.1 Å²	115.1	84%	0.84	67%	0.669	S	S	*	*			trans	15.1	85.4	158.2	-64.2	-19.7	0	0	0	116.2	T253	N251-T253 VanDerWaalsContact C-N 3.28Å; N251-T253 PolarHBondContact O-N 3.22Å
252	I	45.8	Very low	49.5	Very low	168 Å²	168	117.3 Å²	117.3	86%	0.862	68%	0.677	S	S	*	*			trans	-72.6	87.4	168.2	-55.4	177.9	0	0	0	108.4	T250	T250-I252 PolarHBondContact O-N 2.91Å
253	T	39.3	Very low	48.4	Very low	97 Å²	97	119.6 Å²	119.6	60%	0.595	68%	0.684	S	S	*	*			trans	-65.8	136.3	156.8	48	0	0	0	0	108.6	N251 H255	N251-T253 VanDerWaalsContact C-N 3.28Å; N251-T253 PolarHBondContact O-N 3.22Å; T253-H255 PolarHBondContact O-N 3.01Å
254	P	43.1	Very low	47.6	Very low	129 Å²	129	122.8 Å²	122.8	84%	0.838	70%	0.702	S	S	*	*			trans	-77.1	71.2	-176.8	32.9	-36.7	0	0	0	111.5
255	H	37.2	Very low	47.7	Very low	167 Å²	167	121.4 Å²	121.4	77%	0.773	69%	0.692	S	S	*	*			trans	-84.5	112.8	163.9	-101.1	-72.2	0	0	0	109.3	T253 D257	T253-H255 PolarHBondContact O-N 3.01Å; H255-D257 PolarHBondContact O-N 3.19Å
256	S	46.8	Very low	48.4	Very low	105 Å²	105	116.4 Å²	116.4	73%	0.734	67%	0.669	S	S	*	*			trans	-76.5	103.1	178	54.5	0	0	0	0	110.8
257	D	36.9	Very low	49.8	Very low	147 Å²	147	117.9 Å²	117.9	79%	0.786	67%	0.668	S	S	*	*			trans	-102.5	141.1	162.5	-90.7	-46.4	0	0	0	110.6	H255 T259	H255-D257 PolarHBondContact O-N 3.19Å; D257-T259 PolarHBondContact O-N 2.72Å; D257-T259 VanDerWaalsContact O-N 3.15Å
258	N	45.8	Very low	51.5	Low	158 Å²	158	117 Å²	117	85%	0.845	65%	0.649	S	S	*	*			trans	-85.9	86.2	-169.2	-69.1	-61.5	0	0	0	112.3
259	T	40.1	Very low	53.9	Low	98 Å²	98	114.1 Å²	114.1	60%	0.601	63%	0.631	S	S	*	*			trans	-116.2	98.6	166.5	46.2	0	0	0	0	111	D257 T261	D257-T259 PolarHBondContact O-N 2.72Å; D257-T259 VanDerWaalsContact O-N 3.15Å; T259-T261 PolarHBondContact O-N 3.12Å
260	T	42.4	Very low	56	Low	138 Å²	138	111.5 Å²	111.5	85%	0.847	61%	0.613	S	S	*	*	T	Hydrogen-bonded Turn	trans	-75.9	58.6	-178.1	56.8	0	0	0	0	112.3
261	T	47.4	Very low	58.3	Low	96 Å²	96	113.5 Å²	113.5	59%	0.589	62%	0.615	S	S	*	*	T	Hydrogen-bonded Turn	trans	-138.3	-21.5	-175.4	47	0	0	0	0	114.7	T259	T259-T261 PolarHBondContact O-N 3.12Å
262	D	50	Low	60.5	Low	97 Å²	97	107.5 Å²	107.5	52%	0.519	58%	0.584	S	S	.	*	S	Bend	trans	-89.6	-27.4	-172.3	-79.5	-16.5	0	0	0	115.2	D264 T265	D262-D264 PolarHBondContact O-N 3.22Å; D262-T265 WeakPolarHBondContact O-CB 3.25Å; D262-T265 WeakPolarHBondContact O-CG2 3.05Å; D262-T265 PolarHBondContact O-N 3.3Å; D262-T265 PolarHBondContact O-OG1 3.39Å
263	D	51.9	Low	62.6	Low	139 Å²	139	106.9 Å²	106.9	74%	0.743	58%	0.575	S	S	*	*	H	α-helix	trans	-55.1	-41.3	178.2	-72.2	-42.8	0	0	0	111.6	T265 C266	D263-T265 PolarHBondContact O-N 3.02Å; D263-C266 PolarHBondContact O-N 3.12Å
264	D	61.5	Low	64.9	Low	100 Å²	100	105.7 Å²	105.7	54%	0.535	57%	0.565	S	S	.	*	H	α-helix	trans	-64	-11.6	-178.3	-140.5	78	0	0	0	113.7	D262 K269	D262-D264 PolarHBondContact O-N 3.22Å; D264-K269 WeakPolarHBondContact O-CE 3.05Å; D264-K269 PolarHBondContact O-NZ 3.1Å; D264-K269 IonicContact OD2-NZ 2.66Å; D264-K269 PolarHBondContact OD2-NZ 3.41Å
265	T	70.9	Confident	66.9	Low	27 Å²	27	102.6 Å²	102.6	17%	0.166	55%	0.547	C	S	.	.	H	α-helix	trans	-86.1	-23.1	176.6	73.6	0	0	0	0	113.2	D262 D263 N336 I337	D262-T265 WeakPolarHBondContact O-CB 3.25Å; D262-T265 WeakPolarHBondContact O-CG2 3.05Å; D262-T265 PolarHBondContact O-N 3.3Å; D262-T265 PolarHBondContact O-OG1 3.39Å; D263-T265 PolarHBondContact O-N 3.02Å; T265-N336 VanDerWaalsContact O-CB 3.3Å; T265-N336 WeakPolarHBondContact O-CB 3.34Å; T265-N336 PolarHBondContact O-ND2 2.82Å; T265-I337 HydrophobicContact CG2-CD1 4.06Å
266	C	77.5	Confident	69.3	Low	43 Å²	43	97.8 Å²	97.8	29%	0.291	52%	0.524	S	S	.	.	H	α-helix	trans	-102.8	-15.5	-170.6	-69.2	0	0	0	0	113.5	C241 D263 N336	C241-C266 HydrophobicContact CB-CB 4.28Å; D263-C266 PolarHBondContact O-N 3.12Å; C266-N336 VanDerWaalsContact C-ND2 3.34Å; C266-N336 WeakPolarHBondContact CA-ND2 3.48Å; C266-N336 PolarHBondContact O-ND2 2.88Å
267	E	82.9	Confident	71.3	Confident	126 Å²	126	94 Å²	94	59%	0.589	50%	0.497	S	S	*	.	S	Bend	trans	-78.4	138.2	178.1	-65.1	-152	142.4	0	0	114	K269	E267-K269 PolarHBondContact O-N 3.39Å
268	P	86.7	Confident	73.9	Confident	54 Å²	54	88.6 Å²	88.6	35%	0.351	47%	0.473	S	S	.	.			trans	-76.3	114	177.1	30.1	-33.6	0	0	0	111.8	I99 Y332 L333	I99-P268 HydrophobicContact CD1-CB 3.85Å; P268-Y332 HydrophobicContact CB-CE1 4.35Å; P268-L333 HydrophobicContact CB-CD2 3.76Å
269	K	90.4	Very high	76.1	Confident	62 Å²	62	81.1 Å²	81.1	27%	0.27	43%	0.432	S	S	.	.			trans	-87.1	123.1	-176.4	-56.1	-168.5	-177.8	178.8	0	110.5	G98 I99 D264 E267 V272 Y332	G98-K269 CarbonylContact C-O 3.58Å; G98-K269 WeakPolarHBondContact CA-O 3.33Å; I99-K269 PolarHBondContact N-O 2.66Å; D264-K269 WeakPolarHBondContact O-CE 3.05Å; D264-K269 PolarHBondContact O-NZ 3.1Å; D264-K269 IonicContact OD2-NZ 2.66Å; D264-K269 PolarHBondContact OD2-NZ 3.41Å; E267-K269 PolarHBondContact O-N 3.39Å; K269-V272 HydrophobicContact CB-CG2 3.8Å; K269-Y332 PolarHBondContact N-OH 3.26Å
270	Y	90.8	Very high	78.7	Confident	150 Å²	150	76.5 Å²	76.5	59%	0.588	41%	0.405	S	S	*	.	S	Bend	trans	-75.6	-32.9	-175.8	-72.6	-89.8	0	0	0	113.3	G98 I99 A100	G98-Y270 CarbonylContact C-O 3.31Å; G98-Y270 VanDerWaalsContact C-O 3.31Å; I99-Y270 PolarHBondContact N-O 2.9Å; A100-Y270 HydrophobicContact CB-CD1 4.4Å; A100-Y270 WeakPolarHBondContact CB-O 3.36Å; A100-Y270 PolarHBondContact N-O 3.31Å
271	F	92.6	Very high	81.2	Confident	126 Å²	126	71.8 Å²	71.8	55%	0.553	38%	0.376	S	S	*	.			trans	-134.4	131.8	176.5	-62.9	-82.6	0	0	0	109.1	T97 A100 L101 F273	T97-F271 CarbonylContact O-C 3.54Å; T97-F271 WeakPolarHBondContact O-CA 3.5Å; A100-F271 HydrophobicContact CB-CE1 4Å; A100-F271 HydrophobicContact CB-CE2 4.08Å; A100-F271 HydrophobicContact CB-CZ 3.72Å; L101-F271 HydrophobicContact CB-CD1 4.09Å; L101-F271 HydrophobicContact CB-CE1 4.38Å; F271-F273 HydrophobicContact CB-CE2 4.31Å
272	V	90.8	Very high	83.6	Confident	30 Å²	30	67.2 Å²	67.2	18%	0.182	35%	0.347	C	S	.	.			trans	-137.3	136	176	-179.8	0	0	0	0	107.6	T97 K269	T97-V272 CarbonylContact C-O 3.2Å; T97-V272 WeakPolarHBondContact CA-O 3.42Å; T97-V272 PolarHBondContact O-N 3.37Å; K269-V272 HydrophobicContact CB-CG2 3.8Å
273	F	89.7	Confident	85.8	Confident	155 Å²	155	62.7 Å²	62.7	68%	0.68	32%	0.323	S	S	*	.			trans	-134.1	115.3	174.8	-64.6	-79.8	0	0	0	108.9	L101 F271 T277	L101-F273 HydrophobicContact CD2-CD1 4.46Å; L101-F273 HydrophobicContact CD2-CE1 3.67Å; L101-F273 HydrophobicContact CD2-CZ 3.89Å; F271-F273 HydrophobicContact CB-CE2 4.31Å; F273-T277 HydrophobicContact CD1-CG2 4.43Å
274	N	87.3	Confident	87.9	Confident	73 Å²	73	56 Å²	56	39%	0.39	29%	0.288	S	S	.	.	S	Bend	trans	-146.1	-175.7	177.8	66.5	24.8	0	0	0	109.7	N96 Q276 T277	N96-N274 PolarHBondContact OD1-ND2 3.19Å; N96-N274 PolarHBondContact OD1-OD1 3.39Å; N274-Q276 VanDerWaalsContact C-N 3.27Å; N274-Q276 PolarHBondContact O-N 3.47Å; N274-Q276 WeakPolarHBondContact OD1-CA 3.27Å; N274-Q276 WeakPolarHBondContact OD1-CB 3.32Å; N274-Q276 PolarHBondContact OD1-N 2.93Å; N274-T277 PolarHBondContact N-OG1 2.97Å; N274-T277 WeakPolarHBondContact O-CB 3.35Å; N274-T277 PolarHBondContact O-N 3.33Å; N274-T277 PolarHBondContact O-OG1 2.85Å; N274-T277 VanDerWaalsContact O-OG1 3.12Å; N274-T277 PolarHBondContact OD1-N 3.31Å; N274-T277 PolarHBondContact OD1-OG1 3.07Å
275	S	84.9	Confident	89.5	Confident	64 Å²	64	51.3 Å²	51.3	45%	0.448	26%	0.262	S	S	.	.	G	3₁₀ helix	trans	-64.2	-33.7	178.4	71.4	0	0	0	0	112.6	T277 A278 D481	S275-T277 VanDerWaalsContact C-N 3.3Å; S275-T277 PolarHBondContact O-N 2.84Å; S275-A278 VanDerWaalsContact O-CB 3.28Å; S275-A278 WeakPolarHBondContact O-CB 3.43Å; S275-A278 PolarHBondContact O-N 3.41Å; S275-D481 VanDerWaalsContact CB-OD1 3.24Å; S275-D481 WeakPolarHBondContact CB-OD1 3.38Å; S275-D481 PolarHBondContact OG-OD1 2.59Å
276	Q	87.6	Confident	90.7	Very high	65 Å²	65	50.5 Å²	50.5	30%	0.304	26%	0.257	S	S	.	.	G	3₁₀ helix	trans	-74.8	-18.6	-176.9	-56.3	-173.8	12.8	0	0	112.8	F92 N96 N274 A278 Y279	F92-Q276 HydrophobicContact CZ-CB 4.23Å; N96-Q276 HydrophobicContact CB-CB 4.16Å; N96-Q276 PolarHBondContact ND2-OE1 3.33Å; N96-Q276 WeakPolarHBondContact OD1-CB 3.23Å; N274-Q276 VanDerWaalsContact C-N 3.27Å; N274-Q276 PolarHBondContact O-N 3.47Å; N274-Q276 WeakPolarHBondContact OD1-CA 3.27Å; N274-Q276 WeakPolarHBondContact OD1-CB 3.32Å; N274-Q276 PolarHBondContact OD1-N 2.93Å; Q276-A278 PolarHBondContact O-N 3.33Å; Q276-A278 VanDerWaalsContact O-N 3.1Å; Q276-Y279 WeakPolarHBondContact O-CD2 3.41Å; Q276-Y279 PolarHBondContact O-N 3.39Å
277	T	89.8	Confident	91.6	Very high	27 Å²	27	48.5 Å²	48.5	17%	0.166	24%	0.243	C	C	.	.	G	3₁₀ helix	trans	-52.6	-29.4	168.7	-46.5	0	0	0	0	111.8	N96 T97 F273 N274 S275 Y279 A280	N96-T277 WeakPolarHBondContact O-CB 3.48Å; N96-T277 PolarHBondContact O-OG1 3.48Å; T97-T277 HydrophobicContact CG2-CG2 4.04Å; F273-T277 HydrophobicContact CD1-CG2 4.43Å; N274-T277 PolarHBondContact N-OG1 2.97Å; N274-T277 WeakPolarHBondContact O-CB 3.35Å; N274-T277 PolarHBondContact O-N 3.33Å; N274-T277 PolarHBondContact O-OG1 2.85Å; N274-T277 VanDerWaalsContact O-OG1 3.12Å; N274-T277 PolarHBondContact OD1-N 3.31Å; N274-T277 PolarHBondContact OD1-OG1 3.07Å; S275-T277 VanDerWaalsContact C-N 3.3Å; S275-T277 PolarHBondContact O-N 2.84Å; T277-Y279 PolarHBondContact O-N 3.19Å; T277-A280 WeakPolarHBondContact O-CB 3.33Å; T277-A280 PolarHBondContact O-N 3.04Å; T277-A280 VanDerWaalsContact O-N 3.08Å
278	A	90.5	Very high	92.2	Very high	33 Å²	33	42.5 Å²	42.5	27%	0.273	22%	0.215	S	C	.	.	G	3₁₀ helix	trans	-59.2	-25.3	175.9	0	0	0	0	0	114.2	S275 Q276 P282	S275-A278 VanDerWaalsContact O-CB 3.28Å; S275-A278 WeakPolarHBondContact O-CB 3.43Å; S275-A278 PolarHBondContact O-N 3.41Å; Q276-A278 PolarHBondContact O-N 3.33Å; Q276-A278 VanDerWaalsContact O-N 3.1Å; A278-P282 VanDerWaalsContact O-CD 3.23Å; A278-P282 WeakPolarHBondContact O-CD 3.48Å
279	Y	92.6	Very high	92.6	Very high	0 Å²	0	40.5 Å²	40.5	0%	0	20%	0.202	C	C	.	.	G	3₁₀ helix	trans	-84.7	-15.7	178.1	-63.9	-100.7	0	0	0	113.1	Q276 T277 V281 P282 I283 R420 Y421 V478 D481	Q276-Y279 WeakPolarHBondContact O-CD2 3.41Å; Q276-Y279 PolarHBondContact O-N 3.39Å; T277-Y279 PolarHBondContact O-N 3.19Å; Y279-V281 PolarHBondContact O-N 3.04Å; Y279-P282 WeakPolarHBondContact O-CD 3.49Å; Y279-I283 WeakPolarHBondContact O-CB 3.49Å; Y279-I283 WeakPolarHBondContact O-CD1 3.42Å; Y279-I283 WeakPolarHBondContact O-CG1 3.41Å; Y279-I283 PolarHBondContact O-N 2.71Å; Y279-R420 HydrophobicContact CD1-CB 4.47Å; Y279-R420 VanDerWaalsContact CD1-O 3.31Å; Y279-R420 WeakPolarHBondContact CD1-O 3.27Å; Y279-R420 HydrophobicContact CE1-CG 4.23Å; Y279-Y421 HydrophobicContact CE1-CD1 4.18Å; Y279-Y421 WeakPolarHBondContact OH-CE1 3.36Å; Y279-V478 HydrophobicContact CD1-CG2 4.03Å; Y279-V478 HydrophobicContact CE1-CB 4.49Å; Y279-V478 HydrophobicContact CE1-CG1 3.97Å; Y279-V478 HydrophobicContact CE1-CG2 4.09Å; Y279-V478 HydrophobicContact CG-CG2 4.45Å; Y279-D481 HydrophobicContact CE2-CB 3.81Å; Y279-D481 WeakPolarHBondContact CE2-OD2 3.43Å; Y279-D481 PolarHBondContact OH-OD2 3.33Å
280	A	95	Very high	92.7	Very high	2 Å²	2	37.6 Å²	37.6	2%	0.017	19%	0.189	C	C	.	.	H	α-helix	trans	-63	-43.6	-173.5	0	0	0	0	0	112.6	A93 T97 T277 I283 L284	A93-A280 HydrophobicContact CB-CB 4.14Å; T97-A280 HydrophobicContact CG2-CB 3.41Å; T97-A280 VanDerWaalsContact CG2-CB 3.41Å; T277-A280 WeakPolarHBondContact O-CB 3.33Å; T277-A280 PolarHBondContact O-N 3.04Å; T277-A280 VanDerWaalsContact O-N 3.08Å; A280-I283 PolarHBondContact O-N 3.07Å; A280-L284 WeakPolarHBondContact O-CB 3.45Å; A280-L284 WeakPolarHBondContact O-CD1 3.37Å; A280-L284 VanDerWaalsContact O-CG 3.25Å; A280-L284 WeakPolarHBondContact O-CG 3.18Å; A280-L284 PolarHBondContact O-N 3.11Å
281	V	95.3	Very high	92.8	Very high	39 Å²	39	30.5 Å²	30.5	24%	0.236	16%	0.161	C	C	.	.	H	α-helix	trans	-65.8	-49.2	175.8	174.5	0	0	0	0	111.5	L105 Y279 I283 L284 T285 V470	L105-V281 HydrophobicContact CD1-CG2 4.38Å; L105-V281 HydrophobicContact CD2-CG2 4.12Å; Y279-V281 PolarHBondContact O-N 3.04Å; V281-I283 PolarHBondContact O-N 3.13Å; V281-L284 PolarHBondContact O-N 3.21Å; V281-T285 HydrophobicContact CG1-CG2 4.3Å; V281-T285 WeakPolarHBondContact O-CG2 3.39Å; V281-T285 PolarHBondContact O-N 3.09Å; V281-T285 PolarHBondContact O-OG1 3.03Å; V281-V470 HydrophobicContact CG1-CG1 3.86Å
282	P	96.4	Very high	92.6	Very high	0 Å²	0	24.9 Å²	24.9	0%	0	14%	0.138	C	C	.	.	H	α-helix	trans	-51.4	-47.1	169.4	-32.6	36.5	0	0	0	115.6	A278 Y279 L284 T285 F286 F423 G427 A428 V478	A278-P282 VanDerWaalsContact O-CD 3.23Å; A278-P282 WeakPolarHBondContact O-CD 3.48Å; Y279-P282 WeakPolarHBondContact O-CD 3.49Å; P282-L284 VanDerWaalsContact C-N 3.32Å; P282-L284 PolarHBondContact O-N 3.29Å; P282-T285 WeakPolarHBondContact CA-OG1 3.18Å; P282-T285 PolarHBondContact O-N 3.35Å; P282-T285 PolarHBondContact O-OG1 3.19Å; P282-T285 VanDerWaalsContact O-OG1 3.08Å; P282-F286 WeakPolarHBondContact O-CB 3.29Å; P282-F286 PolarHBondContact O-N 3.16Å; P282-F423 WeakPolarHBondContact CB-O 3.28Å; P282-G427 VanDerWaalsContact O-CA 3.27Å; P282-G427 WeakPolarHBondContact O-CA 3.03Å; P282-A428 HydrophobicContact CG-CB 4.03Å; P282-V478 HydrophobicContact CG-CG2 4.1Å
283	I	96.4	Very high	92.5	Very high	1 Å²	1	24.5 Å²	24.5	1%	0.005	14%	0.135	C	C	.	.	H	α-helix	trans	-61.3	-44.1	178.7	-69.5	161.9	0	0	0	109.9	L90 F92 A93 Y279 A280 V281 A287 F423	L90-I283 HydrophobicContact CD2-CG2 4.08Å; F92-I283 HydrophobicContact CD1-CD1 3.76Å; F92-I283 HydrophobicContact CE1-CD1 4.15Å; A93-I283 HydrophobicContact CB-CB 4.39Å; A93-I283 HydrophobicContact CB-CD1 4.16Å; A93-I283 HydrophobicContact CB-CG2 4.19Å; Y279-I283 WeakPolarHBondContact O-CB 3.49Å; Y279-I283 WeakPolarHBondContact O-CD1 3.42Å; Y279-I283 WeakPolarHBondContact O-CG1 3.41Å; Y279-I283 PolarHBondContact O-N 2.71Å; A280-I283 PolarHBondContact O-N 3.07Å; V281-I283 PolarHBondContact O-N 3.13Å; I283-A287 VanDerWaalsContact O-CB 3.26Å; I283-A287 WeakPolarHBondContact O-CB 3.41Å; I283-A287 PolarHBondContact O-N 3.12Å; I283-F423 HydrophobicContact CG1-CB 3.63Å; I283-F423 HydrophobicContact CG1-CD2 4.15Å; I283-F423 HydrophobicContact CG1-CG 4.16Å
284	L	96.5	Very high	92.5	Very high	0 Å²	0	17.1 Å²	17.1	0%	0	10%	0.103	C	C	.	.	H	α-helix	trans	-68.3	-41.4	179.1	-72.6	168.3	0	0	0	113.1	L90 F102 L105 L106 V109 A280 V281 P282 A287 F288	L90-L284 HydrophobicContact CD2-CD2 3.79Å; F102-L284 HydrophobicContact CE2-CD2 4Å; F102-L284 HydrophobicContact CZ-CD2 4.11Å; L105-L284 HydrophobicContact CB-CD1 3.48Å; L105-L284 VanDerWaalsContact CB-CD1 3.48Å; L105-L284 HydrophobicContact CD1-CD1 4.46Å; L106-L284 HydrophobicContact CB-CD2 4.36Å; L106-L284 HydrophobicContact CD1-CD2 3.62Å; V109-L284 HydrophobicContact CB-CB 4.46Å; V109-L284 HydrophobicContact CG1-CB 4.48Å; V109-L284 HydrophobicContact CG2-CB 4.18Å; A280-L284 WeakPolarHBondContact O-CB 3.45Å; A280-L284 WeakPolarHBondContact O-CD1 3.37Å; A280-L284 VanDerWaalsContact O-CG 3.25Å; A280-L284 WeakPolarHBondContact O-CG 3.18Å; A280-L284 PolarHBondContact O-N 3.11Å; V281-L284 PolarHBondContact O-N 3.21Å; P282-L284 VanDerWaalsContact C-N 3.32Å; P282-L284 PolarHBondContact O-N 3.29Å; L284-A287 PolarHBondContact O-N 3.44Å; L284-F288 WeakPolarHBondContact O-CD2 3.33Å; L284-F288 PolarHBondContact O-N 3.13Å
285	T	95.8	Very high	92.7	Very high	0 Å²	0	13.7 Å²	13.7	0%	0	9%	0.085	C	C	.	.	H	α-helix	trans	-67.4	-40.3	175.8	54.8	0	0	0	0	111.1	V109 V281 P282 A287 F288 V289 G427 V432 I435 F436	V109-T285 HydrophobicContact CG1-CG2 4.19Å; V109-T285 HydrophobicContact CG2-CG2 4.48Å; V281-T285 HydrophobicContact CG1-CG2 4.3Å; V281-T285 WeakPolarHBondContact O-CG2 3.39Å; V281-T285 PolarHBondContact O-N 3.09Å; V281-T285 PolarHBondContact O-OG1 3.03Å; P282-T285 WeakPolarHBondContact CA-OG1 3.18Å; P282-T285 PolarHBondContact O-N 3.35Å; P282-T285 PolarHBondContact O-OG1 3.19Å; P282-T285 VanDerWaalsContact O-OG1 3.08Å; T285-A287 VanDerWaalsContact C-N 3.32Å; T285-A287 PolarHBondContact O-N 3.47Å; T285-F288 PolarHBondContact O-N 3.34Å; T285-V289 PolarHBondContact O-N 3.39Å; T285-G427 PolarHBondContact OG1-O 3.05Å; T285-V432 HydrophobicContact CG2-CG2 4.12Å; T285-I435 HydrophobicContact CG2-CD1 4.48Å; T285-I435 VanDerWaalsContact O-CD1 3.26Å; T285-I435 WeakPolarHBondContact O-CD1 3.44Å; T285-F436 HydrophobicContact CG2-CE2 3.92Å; T285-F436 HydrophobicContact CG2-CZ 4.45Å
286	F	95.8	Very high	92.8	Very high	11 Å²	11	12.6 Å²	12.6	5%	0.048	8%	0.076	C	C	.	.	H	α-helix	trans	-61.5	-38.9	172.7	-171.8	-81.1	0	0	0	112.1	Q155 A159 T162 P282 F288 V289 F423 C426	Q155-F286 VanDerWaalsContact NE2-CD2 3.28Å; A159-F286 HydrophobicContact CB-CZ 4.09Å; T162-F286 HydrophobicContact CG2-CE1 4.43Å; T162-F286 HydrophobicContact CG2-CZ 4.09Å; P282-F286 WeakPolarHBondContact O-CB 3.29Å; P282-F286 PolarHBondContact O-N 3.16Å; F286-F288 VanDerWaalsContact C-N 3.29Å; F286-F288 PolarHBondContact O-N 3.13Å; F286-V289 VanDerWaalsContact O-CG1 3.29Å; F286-V289 WeakPolarHBondContact O-CG1 3.46Å; F286-F423 AromaticContact CD1-CD1 3.58Å; F286-F423 HydrophobicContact CD1-CD1 3.58Å; F286-F423 AromaticContact CD1-CE1 3.82Å; F286-F423 HydrophobicContact CD1-CE1 3.82Å; F286-F423 HydrophobicContact CD2-CD1 4.46Å; F286-F423 AromaticContact CE1-CD1 3.69Å; F286-F423 HydrophobicContact CE1-CD1 3.69Å; F286-F423 AromaticContact CE1-CE1 3.64Å; F286-F423 HydrophobicContact CE1-CE1 3.64Å; F286-F423 AromaticContact CG-CD1 4Å; F286-F423 HydrophobicContact CG-CD1 4Å; F286-F423 HydrophobicContact CZ-CD1 4.16Å; F286-F423 HydrophobicContact CZ-CE1 4.33Å; F286-C426 HydrophobicContact CD2-CB 3.67Å; F286-C426 HydrophobicContact CE2-CB 3.61Å
287	A	95.5	Very high	92.8	Very high	1 Å²	1	10 Å²	10	1%	0.008	6%	0.064	C	C	.	.	H	α-helix	trans	-73.8	-11.2	179.9	0	0	0	0	0	114.6	I82 L90 I283 L284 T285 Y324	I82-A287 VanDerWaalsContact O-O 3.05Å; L90-A287 HydrophobicContact CD2-CB 4.13Å; I283-A287 VanDerWaalsContact O-CB 3.26Å; I283-A287 WeakPolarHBondContact O-CB 3.41Å; I283-A287 PolarHBondContact O-N 3.12Å; L284-A287 PolarHBondContact O-N 3.44Å; T285-A287 VanDerWaalsContact C-N 3.32Å; T285-A287 PolarHBondContact O-N 3.47Å; A287-Y324 HydrophobicContact CB-CE2 3.81Å; A287-Y324 VanDerWaalsContact O-CE2 3.23Å; A287-Y324 WeakPolarHBondContact O-CE2 3.41Å; A287-Y324 PolarHBondContact O-OH 3.36Å
288	F	95.6	Very high	92.8	Very high	0 Å²	0	9.2 Å²	9.2	0%	0	6%	0.058	C	C	.	.	T	Hydrogen-bonded Turn	trans	-116.9	8.9	-178.4	-80.5	-60.5	0	0	0	114.6	I82 L106 V109 A110 L284 T285 F286 C290 F317 Y324	I82-F288 HydrophobicContact CG2-CD1 3.9Å; I82-F288 HydrophobicContact CG2-CE1 4.39Å; L106-F288 HydrophobicContact CD1-CE2 3.82Å; L106-F288 HydrophobicContact CD1-CZ 4.06Å; L106-F288 HydrophobicContact CG-CE2 4.48Å; V109-F288 HydrophobicContact CB-CD2 4.24Å; V109-F288 HydrophobicContact CG1-CB 4.21Å; V109-F288 HydrophobicContact CG1-CD2 3.73Å; V109-F288 HydrophobicContact CG1-CG 4.4Å; A110-F288 HydrophobicContact CB-CE1 4.18Å; A110-F288 HydrophobicContact CB-CE2 4.09Å; A110-F288 HydrophobicContact CB-CZ 3.79Å; L284-F288 WeakPolarHBondContact O-CD2 3.33Å; L284-F288 PolarHBondContact O-N 3.13Å; T285-F288 PolarHBondContact O-N 3.34Å; F286-F288 VanDerWaalsContact C-N 3.29Å; F286-F288 PolarHBondContact O-N 3.13Å; F288-C290 PolarHBondContact O-N 2.76Å; F288-C290 VanDerWaalsContact O-N 3.13Å; F288-F317 HydrophobicContact CB-CE1 4.13Å; F288-F317 AromaticContact CD1-CD1 3.67Å; F288-F317 HydrophobicContact CD1-CD1 3.67Å; F288-F317 AromaticContact CD1-CE1 3.58Å; F288-F317 HydrophobicContact CD1-CE1 3.58Å; F288-F317 HydrophobicContact CE1-CD1 4Å; F288-F317 HydrophobicContact CE1-CE1 4.37Å; F288-F317 HydrophobicContact CG-CE1 4.21Å; F288-Y324 HydrophobicContact CD1-CD2 4.48Å; F288-Y324 HydrophobicContact CD1-CE2 4.03Å; F288-Y324 AromaticContact CE1-CD2 3.79Å; F288-Y324 HydrophobicContact CE1-CD2 3.79Å; F288-Y324 AromaticContact CE1-CE2 3.76Å; F288-Y324 HydrophobicContact CE1-CE2 3.76Å; F288-Y324 HydrophobicContact CE2-CD2 4.08Å; F288-Y324 HydrophobicContact CE2-CE2 4.32Å; F288-Y324 HydrophobicContact CG-CE2 4.42Å; F288-Y324 AromaticContact CZ-CD2 3.56Å; F288-Y324 HydrophobicContact CZ-CD2 3.56Å; F288-Y324 AromaticContact CZ-CE2 3.93Å; F288-Y324 HydrophobicContact CZ-CE2 3.93Å
289	V	94.4	Very high	92.6	Very high	12 Å²	12	11.3 Å²	11.3	7%	0.073	6%	0.062	C	C	.	.			trans	-88.3	72.8	-172.4	68	0	0	0	0	114.8	Q155 T285 F286 H291 A431 L434 I435	Q155-V289 HydrophobicContact CG-CG1 3.67Å; Q155-V289 HydrophobicContact CG-CG2 4.15Å; Q155-V289 VanDerWaalsContact NE2-CG1 3.29Å; T285-V289 PolarHBondContact O-N 3.39Å; F286-V289 VanDerWaalsContact O-CG1 3.29Å; F286-V289 WeakPolarHBondContact O-CG1 3.46Å; V289-H291 VanDerWaalsContact C-N 3.28Å; V289-H291 HydrophobicContact CG2-CB 4.48Å; V289-H291 PolarHBondContact O-N 2.92Å; V289-A431 HydrophobicContact CB-CB 4.14Å; V289-A431 HydrophobicContact CG1-CB 4.22Å; V289-A431 HydrophobicContact CG2-CB 4.29Å; V289-L434 HydrophobicContact CG2-CB 3.88Å; V289-L434 HydrophobicContact CG2-CD1 3.92Å; V289-I435 HydrophobicContact CB-CD1 4.11Å; V289-I435 HydrophobicContact CB-CG1 4.38Å; V289-I435 HydrophobicContact CG2-CD1 4.44Å; V289-I435 HydrophobicContact CG2-CG1 4.23Å
290	C	93.1	Very high	92.3	Very high	1 Å²	1	15.8 Å²	15.8	1%	0.007	8%	0.083	C	C	.	.			trans	-83	1.8	170.7	67.7	0	0	0	0	114.8	L78 A81 I82 F288 P292 T293 I294 F317	L78-C290 HydrophobicContact CD1-CB 3.68Å; A81-C290 HydrophobicContact CB-CB 4.47Å; I82-C290 HydrophobicContact CG1-CB 3.69Å; F288-C290 PolarHBondContact O-N 2.76Å; F288-C290 VanDerWaalsContact O-N 3.13Å; C290-P292 VanDerWaalsContact C-CD 3.4Å; C290-P292 VanDerWaalsContact C-N 3.35Å; C290-T293 PolarHBondContact O-N 2.88Å; C290-T293 VanDerWaalsContact O-N 3.11Å; C290-T293 PolarHBondContact O-OG1 3.18Å; C290-T293 VanDerWaalsContact O-OG1 3.13Å; C290-I294 PolarHBondContact O-N 2.83Å; C290-F317 VanDerWaalsContact SG-CE2 3.56Å; C290-F317 VanDerWaalsContact SG-CZ 3.59Å
291	H	92.9	Very high	92	Very high	0 Å²	0	15.7 Å²	15.7	0%	0	8%	0.082	C	C	.	.	T	Hydrogen-bonded Turn	trans	-56.6	-31.4	-173.3	-64.9	83.2	0	0	0	115.6	S116 Y132 V289 L434	S116-H291 WeakPolarHBondContact CB-NE2 3.31Å; S116-H291 PolarHBondContact OG-NE2 2.71Å; Y132-H291 HydrophobicContact CE2-CB 4.31Å; V289-H291 VanDerWaalsContact C-N 3.28Å; V289-H291 HydrophobicContact CG2-CB 4.48Å; V289-H291 PolarHBondContact O-N 2.92Å; H291-L434 HydrophobicContact CB-CB 4.18Å
292	P	89.8	Confident	91.6	Very high	9 Å²	9	19 Å²	19	6%	0.058	9%	0.094	C	C	.	.	T	Hydrogen-bonded Turn	trans	-66.1	-36.2	172.7	-26.6	37.7	0	0	0	115.2	I152 C290 P378 L434	I152-P292 HydrophobicContact CG1-CB 4.43Å; I152-P292 HydrophobicContact CG1-CG 4.41Å; I152-P292 HydrophobicContact CG2-CB 4.1Å; C290-P292 VanDerWaalsContact C-CD 3.4Å; C290-P292 VanDerWaalsContact C-N 3.35Å; P292-P378 HydrophobicContact CB-CB 4.45Å; P292-L434 HydrophobicContact CG-CD1 3.93Å
293	T	87.6	Confident	91.2	Very high	21 Å²	21	22.9 Å²	22.9	13%	0.129	11%	0.114	C	C	.	.	T	Hydrogen-bonded Turn	trans	-95	-18.6	-171.3	57	0	0	0	0	113.2	A81 C290 L295 P296 M297 P378	A81-T293 HydrophobicContact CB-CG2 4.3Å; A81-T293 WeakPolarHBondContact CB-OG1 3.41Å; C290-T293 PolarHBondContact O-N 2.88Å; C290-T293 VanDerWaalsContact O-N 3.11Å; C290-T293 PolarHBondContact O-OG1 3.18Å; C290-T293 VanDerWaalsContact O-OG1 3.13Å; T293-L295 PolarHBondContact O-N 3.08Å; T293-P296 WeakPolarHBondContact O-CD 3.48Å; T293-M297 WeakPolarHBondContact O-CB 3.31Å; T293-M297 PolarHBondContact O-N 3.44Å; T293-P378 HydrophobicContact CG2-CG 4.02Å
294	I	90.7	Very high	90.7	Very high	0 Å²	0	26.2 Å²	26.2	0%	0	13%	0.127	C	C	.	.	H	α-helix	trans	-69.3	-29.3	-171.5	-157.3	172.6	0	0	0	114.5	L78 V117 L120 C290 Y298 M309 A313	L78-I294 HydrophobicContact CD1-CG1 4.29Å; V117-I294 HydrophobicContact CB-CD1 4.05Å; V117-I294 HydrophobicContact CG1-CD1 3.39Å; V117-I294 HydrophobicContact CG2-CD1 3.51Å; L120-I294 HydrophobicContact CD2-CG2 3.87Å; C290-I294 PolarHBondContact O-N 2.83Å; I294-Y298 WeakPolarHBondContact O-CB 3.48Å; I294-Y298 PolarHBondContact O-N 3.43Å; I294-M309 HydrophobicContact CD1-CE 4.44Å; I294-M309 HydrophobicContact CG1-CE 3.54Å; I294-A313 HydrophobicContact CD1-CB 4.46Å
295	L	90.4	Very high	90.5	Very high	1 Å²	1	28.8 Å²	28.8	1%	0.005	15%	0.145	C	C	.	.	H	α-helix	trans	-77.9	-45.9	177.9	-65.4	-179.2	0	0	0	112.9	L120 L121 A124 L130 Y132 L135 T293 M297 Y298 E299	L120-L295 HydrophobicContact CD1-CD1 4.16Å; L120-L295 HydrophobicContact CD2-CD1 4.31Å; L120-L295 HydrophobicContact CD2-CG 4.19Å; L120-L295 HydrophobicContact CG-CD1 4.16Å; L120-L295 HydrophobicContact CG-CD2 4.19Å; L120-L295 HydrophobicContact CG-CG 4.26Å; L121-L295 HydrophobicContact CD2-CD2 4.28Å; A124-L295 HydrophobicContact CB-CD2 3.69Å; L130-L295 VanDerWaalsContact O-CB 3.24Å; L130-L295 WeakPolarHBondContact O-CB 3.5Å; Y132-L295 HydrophobicContact CD2-CD1 4.16Å; Y132-L295 HydrophobicContact CG-CD1 4.39Å; L135-L295 HydrophobicContact CD2-CD1 4.37Å; T293-L295 PolarHBondContact O-N 3.08Å; L295-M297 VanDerWaalsContact C-N 3.29Å; L295-M297 PolarHBondContact O-N 3.48Å; L295-Y298 WeakPolarHBondContact O-CB 3.26Å; L295-Y298 PolarHBondContact O-N 3.44Å; L295-Y298 VanDerWaalsContact O-N 3.1Å; L295-E299 PolarHBondContact O-N 2.85Å; L295-E299 VanDerWaalsContact O-N 3.1Å
296	P	86.5	Confident	90.3	Very high	41 Å²	41	33.5 Å²	33.5	27%	0.266	16%	0.162	S	C	.	.	H	α-helix	trans	-54.4	-43	167	-28.3	35.3	0	0	0	112.9	T293 Y298 E299 E300 F377	T293-P296 WeakPolarHBondContact O-CD 3.48Å; P296-Y298 VanDerWaalsContact C-N 3.28Å; P296-Y298 PolarHBondContact O-N 2.86Å; P296-E299 WeakPolarHBondContact O-CA 3.28Å; P296-E299 VanDerWaalsContact O-CB 3.31Å; P296-E299 WeakPolarHBondContact O-CB 3.22Å; P296-E299 PolarHBondContact O-N 2.74Å; P296-E300 PolarHBondContact O-N 3.48Å; P296-F377 HydrophobicContact CB-CE1 4.28Å
297	M	87.8	Confident	90.2	Very high	11 Å²	11	43.4 Å²	43.4	5%	0.054	20%	0.2	C	C	.	.	H	α-helix	trans	-67.1	-27.9	178	-165.3	-178	-54.9	0	0	113.3	N77 L78 T293 L295 E299 L301 M309	N77-M297 HydrophobicContact CB-CE 3.73Å; N77-M297 HydrophobicContact CB-SD 4.26Å; L78-M297 HydrophobicContact CB-CE 4.01Å; L78-M297 HydrophobicContact CB-SD 3.74Å; L78-M297 HydrophobicContact CD1-CE 4.15Å; L78-M297 HydrophobicContact CD1-SD 4.32Å; T293-M297 WeakPolarHBondContact O-CB 3.31Å; T293-M297 PolarHBondContact O-N 3.44Å; L295-M297 VanDerWaalsContact C-N 3.29Å; L295-M297 PolarHBondContact O-N 3.48Å; M297-E299 VanDerWaalsContact C-N 3.35Å; M297-L301 WeakPolarHBondContact O-CB 3.33Å; M297-L301 PolarHBondContact O-N 2.91Å; M297-M309 HydrophobicContact CB-CE 3.88Å; M297-M309 HydrophobicContact CG-CE 3.9Å; M297-M309 HydrophobicContact SD-CE 3.97Å
298	Y	89.8	Confident	90.1	Very high	11 Å²	11	46.8 Å²	46.8	4%	0.043	21%	0.214	C	C	.	.	H	α-helix	trans	-73	-27.6	171.6	-177.1	-143.9	0	0	0	112.5	L121 D125 L130 I294 L295 P296 R304 R306 M309	L121-Y298 HydrophobicContact CD2-CD1 3.66Å; L121-Y298 HydrophobicContact CD2-CE1 4.18Å; L121-Y298 HydrophobicContact CD2-CG 3.89Å; D125-Y298 WeakPolarHBondContact OD1-CE1 3.23Å; D125-Y298 PolarHBondContact OD1-OH 3.47Å; L130-Y298 HydrophobicContact CD2-CD1 3.65Å; L130-Y298 HydrophobicContact CD2-CE1 4Å; I294-Y298 WeakPolarHBondContact O-CB 3.48Å; I294-Y298 PolarHBondContact O-N 3.43Å; L295-Y298 WeakPolarHBondContact O-CB 3.26Å; L295-Y298 PolarHBondContact O-N 3.44Å; L295-Y298 VanDerWaalsContact O-N 3.1Å; P296-Y298 VanDerWaalsContact C-N 3.28Å; P296-Y298 PolarHBondContact O-N 2.86Å; Y298-R304 HydrophobicContact CD2-CB 4.28Å; Y298-R304 HydrophobicContact CE2-CB 4.04Å; Y298-R304 WeakPolarHBondContact O-CB 3.39Å; Y298-R304 WeakPolarHBondContact O-CD 3.23Å; Y298-R306 PolarHBondContact OH-N 3.43Å; Y298-R306 VanDerWaalsContact OH-N 3.09Å; Y298-M309 HydrophobicContact CD2-CB 3.65Å; Y298-M309 HydrophobicContact CD2-CG 3.84Å; Y298-M309 HydrophobicContact CD2-SD 4.47Å; Y298-M309 HydrophobicContact CE2-CB 4.06Å; Y298-M309 HydrophobicContact CG-CB 4.33Å; Y298-M309 HydrophobicContact CG-CG 4.08Å
299	E	87.7	Confident	90.1	Very high	77 Å²	77	46.8 Å²	46.8	36%	0.36	21%	0.214	S	C	.	.	H	α-helix	trans	-70.6	-45.9	171.4	-176.2	123.3	-116.5	0	0	111.5	L130 L295 P296 M297 L301 R304	L130-E299 HydrophobicContact CB-CB 4.38Å; L130-E299 HydrophobicContact CD1-CB 3.86Å; L130-E299 HydrophobicContact CD1-CG 4.14Å; L130-E299 WeakPolarHBondContact CD1-OE1 3.24Å; L295-E299 PolarHBondContact O-N 2.85Å; L295-E299 VanDerWaalsContact O-N 3.1Å; P296-E299 WeakPolarHBondContact O-CA 3.28Å; P296-E299 VanDerWaalsContact O-CB 3.31Å; P296-E299 WeakPolarHBondContact O-CB 3.22Å; P296-E299 PolarHBondContact O-N 2.74Å; M297-E299 VanDerWaalsContact C-N 3.35Å; E299-L301 VanDerWaalsContact C-N 3.3Å; E299-L301 PolarHBondContact O-N 3.37Å; E299-R304 IonicContact OE1-CZ 3.26Å; E299-R304 IonicContact OE1-NH1 2.76Å; E299-R304 PolarHBondContact OE1-NH1 2.9Å; E299-R304 IonicContact OE1-NH2 2.92Å
300	E	85.8	Confident	90.1	Very high	93 Å²	93	47.6 Å²	47.6	44%	0.435	22%	0.217	S	C	.	.	H	α-helix	trans	-71.3	-16	179.5	-68.3	-178.7	168.9	0	0	114.8	G67 S68 S69 P296 K302	G67-E300 CarbonylContact C-O 3.21Å; G67-E300 WeakPolarHBondContact CA-O 3.35Å; S68-E300 PolarHBondContact N-O 2.95Å; S69-E300 VanDerWaalsContact CB-O 3.26Å; S69-E300 WeakPolarHBondContact CB-O 3.49Å; S69-E300 PolarHBondContact N-O 3.33Å; P296-E300 PolarHBondContact O-N 3.48Å; E300-K302 PolarHBondContact O-N 2.91Å
301	L	88.5	Confident	90.3	Very high	0 Å²	0	51.7 Å²	51.7	0%	0	24%	0.239	C	C	.	.	B	Isolated β-bridge	trans	-69	127.4	-174.4	178.8	64.6	0	0	0	112.8	V71 S74 M297 E299 D303 R304 K308 M309	V71-L301 HydrophobicContact CG2-CD1 4.26Å; S74-L301 WeakPolarHBondContact OG-CD1 3.43Å; M297-L301 WeakPolarHBondContact O-CB 3.33Å; M297-L301 PolarHBondContact O-N 2.91Å; E299-L301 VanDerWaalsContact C-N 3.3Å; E299-L301 PolarHBondContact O-N 3.37Å; L301-D303 PolarHBondContact O-N 3.45Å; L301-R304 HydrophobicContact CB-CB 4.45Å; L301-R304 WeakPolarHBondContact O-CB 3.34Å; L301-R304 PolarHBondContact O-N 2.85Å; L301-K308 HydrophobicContact CD2-CB 3.92Å; L301-M309 HydrophobicContact CD2-CB 4.1Å; L301-M309 HydrophobicContact CD2-SD 3.91Å
302	K	87.4	Confident	90.4	Very high	110 Å²	110	51.7 Å²	51.7	48%	0.478	24%	0.239	S	C	.	.	T	Hydrogen-bonded Turn	trans	-61.7	127.4	179.1	-176.5	168.2	178.4	173.9	0	113.9	G67 S69 E300 K308	G67-K302 WeakPolarHBondContact O-CA 3.36Å; G67-K302 VanDerWaalsContact O-CB 3.28Å; G67-K302 WeakPolarHBondContact O-CB 3.23Å; S69-K302 VanDerWaalsContact O-CB 3.27Å; S69-K302 WeakPolarHBondContact O-CB 3.28Å; S69-K302 PolarHBondContact O-N 2.91Å; E300-K302 PolarHBondContact O-N 2.91Å; K302-K308 PolarHBondContact O-NZ 3.11Å
303	D	87.3	Confident	90.7	Very high	80 Å²	80	51.3 Å²	51.3	43%	0.428	24%	0.236	S	C	.	.	T	Hydrogen-bonded Turn	trans	47.2	59.1	-174.1	-34.8	-49	0	0	0	110.4	Q66 L301 K308	Q66-D303 PolarHBondContact NE2-OD1 3.14Å; L301-D303 PolarHBondContact O-N 3.45Å; D303-K308 PolarHBondContact O-NZ 3.42Å
304	R	86.5	Confident	91.1	Very high	72 Å²	72	53.7 Å²	53.7	27%	0.272	25%	0.248	S	C	.	.			trans	-52.1	135.1	-167.2	68.2	-169.9	-171.2	-165.3	10.6	113.8	L130 Y298 E299 L301	L130-R304 VanDerWaalsContact CD1-CZ 3.44Å; Y298-R304 HydrophobicContact CD2-CB 4.28Å; Y298-R304 HydrophobicContact CE2-CB 4.04Å; Y298-R304 WeakPolarHBondContact O-CB 3.39Å; Y298-R304 WeakPolarHBondContact O-CD 3.23Å; E299-R304 IonicContact OE1-CZ 3.26Å; E299-R304 IonicContact OE1-NH1 2.76Å; E299-R304 PolarHBondContact OE1-NH1 2.9Å; E299-R304 IonicContact OE1-NH2 2.92Å; L301-R304 HydrophobicContact CB-CB 4.45Å; L301-R304 WeakPolarHBondContact O-CB 3.34Å; L301-R304 PolarHBondContact O-N 2.85Å
305	S	92.2	Very high	91.4	Very high	53 Å²	53	56.6 Å²	56.6	37%	0.371	27%	0.266	S	S	.	.			trans	-155.5	137.3	175.6	175.4	0	0	0	0	110.2	R307 K308 M309	S305-R307 PolarHBondContact O-N 2.66Å; S305-R307 VanDerWaalsContact O-N 3.08Å; S305-K308 WeakPolarHBondContact O-CA 3.46Å; S305-K308 WeakPolarHBondContact O-CB 3.37Å; S305-K308 PolarHBondContact O-N 3.18Å; S305-M309 PolarHBondContact O-N 3.27Å
306	R	92.1	Very high	91.7	Very high	99 Å²	99	56.6 Å²	56.6	37%	0.374	27%	0.266	S	S	.	.	H	α-helix	trans	-49.9	-35.6	176.4	-174	176.9	74	-104.2	1.8	113.3	L121 D125 Y298 M309 Q310	L121-R306 HydrophobicContact CB-CG 4.05Å; D125-R306 WeakPolarHBondContact OD2-CB 3.27Å; D125-R306 WeakPolarHBondContact OD2-CD 3.27Å; D125-R306 IonicContact OD2-CZ 3.29Å; D125-R306 IonicContact OD2-NE 3.53Å; D125-R306 IonicContact OD2-NH1 2.71Å; D125-R306 PolarHBondContact OD2-NH1 3.07Å; Y298-R306 PolarHBondContact OH-N 3.43Å; Y298-R306 VanDerWaalsContact OH-N 3.09Å; R306-M309 PolarHBondContact O-N 3.12Å; R306-Q310 VanDerWaalsContact O-CB 3.22Å; R306-Q310 WeakPolarHBondContact O-CB 3.49Å; R306-Q310 PolarHBondContact O-N 3.39Å
307	R	93.1	Very high	92.1	Very high	220 Å²	220	54.8 Å²	54.8	83%	0.83	25%	0.254	S	S	*	.	H	α-helix	trans	-67.6	-38.4	177.1	-173.4	175.8	178.9	177.4	-0.1	112.3	S305 N311	S305-R307 PolarHBondContact O-N 2.66Å; S305-R307 VanDerWaalsContact O-N 3.08Å; R307-N311 WeakPolarHBondContact O-CB 3.35Å; R307-N311 PolarHBondContact O-N 3.06Å; R307-N311 VanDerWaalsContact O-N 3.16Å
308	K	93.8	Very high	92.6	Very high	72 Å²	72	59.4 Å²	59.4	31%	0.313	28%	0.278	S	S	.	.	H	α-helix	trans	-66.9	-48	173.8	-69.1	178.4	172.3	178.1	0	110.6	L301 K302 D303 S305 Q310 N311 V312	L301-K308 HydrophobicContact CD2-CB 3.92Å; K302-K308 PolarHBondContact O-NZ 3.11Å; D303-K308 PolarHBondContact O-NZ 3.42Å; S305-K308 WeakPolarHBondContact O-CA 3.46Å; S305-K308 WeakPolarHBondContact O-CB 3.37Å; S305-K308 PolarHBondContact O-N 3.18Å; K308-Q310 PolarHBondContact O-N 2.98Å; K308-N311 WeakPolarHBondContact O-CA 3.48Å; K308-N311 WeakPolarHBondContact O-CB 3.42Å; K308-N311 PolarHBondContact O-N 3.39Å; K308-V312 WeakPolarHBondContact O-CG2 3.47Å; K308-V312 PolarHBondContact O-N 2.91Å
309	M	94.6	Very high	92.8	Very high	0 Å²	0	60.8 Å²	60.8	0%	0	29%	0.292	C	S	.	.	H	α-helix	trans	-67.7	-37.1	-177.2	-163.6	62.9	-168.4	0	0	112.6	L121 I294 M297 Y298 L301 S305 R306 N311 V312 A313	L121-M309 HydrophobicContact CD1-CB 4.08Å; L121-M309 HydrophobicContact CD1-CG 3.97Å; L121-M309 HydrophobicContact CD2-CB 4.34Å; L121-M309 HydrophobicContact CD2-CG 3.84Å; I294-M309 HydrophobicContact CD1-CE 4.44Å; I294-M309 HydrophobicContact CG1-CE 3.54Å; M297-M309 HydrophobicContact CB-CE 3.88Å; M297-M309 HydrophobicContact CG-CE 3.9Å; M297-M309 HydrophobicContact SD-CE 3.97Å; Y298-M309 HydrophobicContact CD2-CB 3.65Å; Y298-M309 HydrophobicContact CD2-CG 3.84Å; Y298-M309 HydrophobicContact CD2-SD 4.47Å; Y298-M309 HydrophobicContact CE2-CB 4.06Å; Y298-M309 HydrophobicContact CG-CB 4.33Å; Y298-M309 HydrophobicContact CG-CG 4.08Å; L301-M309 HydrophobicContact CD2-CB 4.1Å; L301-M309 HydrophobicContact CD2-SD 3.91Å; S305-M309 PolarHBondContact O-N 3.27Å; R306-M309 PolarHBondContact O-N 3.12Å; M309-N311 VanDerWaalsContact C-N 3.29Å; M309-N311 PolarHBondContact O-N 3.33Å; M309-V312 HydrophobicContact CE-CG1 4.41Å; M309-V312 WeakPolarHBondContact O-CB 3.37Å; M309-V312 PolarHBondContact O-N 3.28Å; M309-V312 HydrophobicContact SD-CB 4.33Å; M309-V312 HydrophobicContact SD-CG1 4.41Å; M309-A313 PolarHBondContact O-N 2.93Å
310	Q	95.4	Very high	93.2	Very high	28 Å²	28	57.2 Å²	57.2	13%	0.131	28%	0.275	C	S	.	.	H	α-helix	trans	-62.1	-37	169.7	-171.5	72	65.3	0	0	111.5	H118 R306 K308 A313 N314	H118-Q310 PolarHBondContact ND1-OE1 2.56Å; R306-Q310 VanDerWaalsContact O-CB 3.22Å; R306-Q310 WeakPolarHBondContact O-CB 3.49Å; R306-Q310 PolarHBondContact O-N 3.39Å; K308-Q310 PolarHBondContact O-N 2.98Å; Q310-A313 PolarHBondContact O-N 2.83Å; Q310-N314 PolarHBondContact NE2-OD1 3.2Å; Q310-N314 WeakPolarHBondContact O-CB 3.44Å; Q310-N314 PolarHBondContact O-N 2.9Å; Q310-N314 PolarHBondContact O-OD1 2.97Å
311	N	95.6	Very high	93.7	Very high	88 Å²	88	54.8 Å²	54.8	47%	0.471	26%	0.263	S	S	.	.	H	α-helix	trans	-68.4	-40.8	176	-165.7	83.6	0	0	0	112.1	R307 K308 M309 A313 N314 V315	R307-N311 WeakPolarHBondContact O-CB 3.35Å; R307-N311 PolarHBondContact O-N 3.06Å; R307-N311 VanDerWaalsContact O-N 3.16Å; K308-N311 WeakPolarHBondContact O-CA 3.48Å; K308-N311 WeakPolarHBondContact O-CB 3.42Å; K308-N311 PolarHBondContact O-N 3.39Å; M309-N311 VanDerWaalsContact C-N 3.29Å; M309-N311 PolarHBondContact O-N 3.33Å; N311-A313 VanDerWaalsContact C-N 3.32Å; N311-A313 PolarHBondContact O-N 2.96Å; N311-N314 PolarHBondContact O-N 3.2Å; N311-V315 WeakPolarHBondContact O-CG2 3.21Å; N311-V315 PolarHBondContact O-N 3.14Å
312	V	95.8	Very high	94.1	Very high	0 Å²	0	58.8 Å²	58.8	0%	0	28%	0.284	C	S	.	.	H	α-helix	trans	-55.2	-48.8	170.7	170.2	0	0	0	0	110.1	V71 I75 L78 K308 M309 S316	V71-V312 HydrophobicContact CG1-CG2 3.88Å; I75-V312 HydrophobicContact CG1-CB 4.22Å; I75-V312 HydrophobicContact CG1-CG1 3.98Å; I75-V312 HydrophobicContact CG1-CG2 4.2Å; L78-V312 HydrophobicContact CB-CG1 4.37Å; L78-V312 HydrophobicContact CD2-CG1 3.89Å; K308-V312 WeakPolarHBondContact O-CG2 3.47Å; K308-V312 PolarHBondContact O-N 2.91Å; M309-V312 HydrophobicContact CE-CG1 4.41Å; M309-V312 WeakPolarHBondContact O-CB 3.37Å; M309-V312 PolarHBondContact O-N 3.28Å; M309-V312 HydrophobicContact SD-CB 4.33Å; M309-V312 HydrophobicContact SD-CG1 4.41Å; V312-S316 WeakPolarHBondContact O-CB 3.33Å; V312-S316 PolarHBondContact O-N 3.21Å; V312-S316 PolarHBondContact O-OG 3.46Å
313	A	96.4	Very high	94.5	Very high	0 Å²	0	54.3 Å²	54.3	0%	0	27%	0.265	C	S	.	.	H	α-helix	trans	-61	-53.2	176.4	0	0	0	0	0	112.5	L78 L114 V117 I294 M309 Q310 N311 V315 S316 F317	L78-A313 HydrophobicContact CD2-CB 4.14Å; L114-A313 HydrophobicContact CD2-CB 4.21Å; V117-A313 HydrophobicContact CG1-CB 3.8Å; I294-A313 HydrophobicContact CD1-CB 4.46Å; M309-A313 PolarHBondContact O-N 2.93Å; Q310-A313 PolarHBondContact O-N 2.83Å; N311-A313 VanDerWaalsContact C-N 3.32Å; N311-A313 PolarHBondContact O-N 2.96Å; A313-V315 VanDerWaalsContact C-N 3.31Å; A313-V315 PolarHBondContact O-N 3.3Å; A313-S316 PolarHBondContact O-N 2.67Å; A313-S316 VanDerWaalsContact O-N 3.15Å; A313-F317 HydrophobicContact CB-CD2 4.47Å; A313-F317 WeakPolarHBondContact O-CB 3.47Å; A313-F317 WeakPolarHBondContact O-CD2 3.04Å; A313-F317 PolarHBondContact O-N 3.43Å
314	N	96.8	Very high	95	Very high	72 Å²	72	50.5 Å²	50.5	39%	0.385	24%	0.244	S	C	.	.	H	α-helix	trans	-56.1	-43.7	-178.3	-69.7	9.3	0	0	0	112.2	Q310 N311 L318	Q310-N314 PolarHBondContact NE2-OD1 3.2Å; Q310-N314 WeakPolarHBondContact O-CB 3.44Å; Q310-N314 PolarHBondContact O-N 2.9Å; Q310-N314 PolarHBondContact O-OD1 2.97Å; N311-N314 PolarHBondContact O-N 3.2Å; N314-L318 VanDerWaalsContact O-CB 3.29Å; N314-L318 WeakPolarHBondContact O-CB 3.39Å; N314-L318 PolarHBondContact O-N 2.95Å; N314-L318 VanDerWaalsContact O-N 3.11Å
315	V	96.6	Very high	95.5	Very high	61 Å²	61	49 Å²	49	37%	0.37	24%	0.242	S	C	.	.	H	α-helix	trans	-68.7	-43.6	177.7	174.8	0	0	0	0	111.4	I75 N311 A313 L318 A319	I75-V315 HydrophobicContact CD1-CB 4.23Å; I75-V315 HydrophobicContact CD1-CG1 4.04Å; I75-V315 HydrophobicContact CG1-CG1 4.48Å; I75-V315 HydrophobicContact CG2-CG1 4.13Å; N311-V315 WeakPolarHBondContact O-CG2 3.21Å; N311-V315 PolarHBondContact O-N 3.14Å; A313-V315 VanDerWaalsContact C-N 3.31Å; A313-V315 PolarHBondContact O-N 3.3Å; V315-L318 PolarHBondContact O-N 3.34Å; V315-A319 WeakPolarHBondContact O-CB 3.41Å; V315-A319 PolarHBondContact O-N 3.07Å
316	S	95.9	Very high	95.7	Very high	0 Å²	0	49.2 Å²	49.2	0%	0	24%	0.238	C	C	.	.	H	α-helix	trans	-65.2	-47.3	-179.4	-51.7	0	0	0	0	111.6	I75 V312 A313 L318 A319 M320	I75-S316 PolarHBondContact O-OG 3.1Å; V312-S316 WeakPolarHBondContact O-CB 3.33Å; V312-S316 PolarHBondContact O-N 3.21Å; V312-S316 PolarHBondContact O-OG 3.46Å; A313-S316 PolarHBondContact O-N 2.67Å; A313-S316 VanDerWaalsContact O-N 3.15Å; S316-L318 VanDerWaalsContact C-N 3.34Å; S316-L318 PolarHBondContact O-N 3.07Å; S316-A319 PolarHBondContact O-N 3.36Å; S316-M320 WeakPolarHBondContact O-CB 3.46Å; S316-M320 VanDerWaalsContact O-CG 3.27Å; S316-M320 WeakPolarHBondContact O-CG 3.2Å; S316-M320 PolarHBondContact O-N 3.05Å
317	F	96.2	Very high	95.9	Very high	3 Å²	3	44.6 Å²	44.6	1%	0.013	22%	0.221	C	C	.	.	H	α-helix	trans	-63.3	-37	176.1	-87.6	-86.6	0	0	0	112.5	I82 L114 V117 F288 C290 A313 F321	I82-F317 HydrophobicContact CD1-CD1 4.23Å; I82-F317 HydrophobicContact CD1-CD2 3.75Å; I82-F317 HydrophobicContact CD1-CE1 4.27Å; I82-F317 HydrophobicContact CD1-CE2 3.82Å; I82-F317 HydrophobicContact CD1-CG 3.97Å; I82-F317 HydrophobicContact CD1-CZ 4.08Å; I82-F317 HydrophobicContact CG1-CE2 4.49Å; I82-F317 HydrophobicContact CG1-CZ 4.37Å; L114-F317 HydrophobicContact CD1-CB 3.87Å; L114-F317 HydrophobicContact CD1-CG 4.32Å; L114-F317 HydrophobicContact CD2-CB 3.82Å; L114-F317 HydrophobicContact CD2-CD2 3.44Å; L114-F317 VanDerWaalsContact CD2-CD2 3.44Å; L114-F317 HydrophobicContact CD2-CE2 4.16Å; L114-F317 HydrophobicContact CD2-CG 3.73Å; L114-F317 HydrophobicContact CG-CB 3.82Å; L114-F317 HydrophobicContact CG-CD1 4.24Å; L114-F317 HydrophobicContact CG-CD2 3.9Å; L114-F317 HydrophobicContact CG-CG 3.73Å; V117-F317 HydrophobicContact CG2-CE2 4.2Å; F288-F317 HydrophobicContact CB-CE1 4.13Å; F288-F317 AromaticContact CD1-CD1 3.67Å; F288-F317 HydrophobicContact CD1-CD1 3.67Å; F288-F317 AromaticContact CD1-CE1 3.58Å; F288-F317 HydrophobicContact CD1-CE1 3.58Å; F288-F317 HydrophobicContact CE1-CD1 4Å; F288-F317 HydrophobicContact CE1-CE1 4.37Å; F288-F317 HydrophobicContact CG-CE1 4.21Å; C290-F317 VanDerWaalsContact SG-CE2 3.56Å; C290-F317 VanDerWaalsContact SG-CZ 3.59Å; A313-F317 HydrophobicContact CB-CD2 4.47Å; A313-F317 WeakPolarHBondContact O-CB 3.47Å; A313-F317 WeakPolarHBondContact O-CD2 3.04Å; A313-F317 PolarHBondContact O-N 3.43Å; F317-F321 WeakPolarHBondContact O-CB 3.12Å; F317-F321 PolarHBondContact O-N 2.86Å
318	L	96.6	Very high	96.1	Very high	108 Å²	108	34.1 Å²	34.1	57%	0.565	18%	0.181	S	C	*	.	H	α-helix	trans	-66.3	-45.3	175.6	179.3	61.3	0	0	0	111.7	N314 V315 S316 F321 I322	N314-L318 VanDerWaalsContact O-CB 3.29Å; N314-L318 WeakPolarHBondContact O-CB 3.39Å; N314-L318 PolarHBondContact O-N 2.95Å; N314-L318 VanDerWaalsContact O-N 3.11Å; V315-L318 PolarHBondContact O-N 3.34Å; S316-L318 VanDerWaalsContact C-N 3.34Å; S316-L318 PolarHBondContact O-N 3.07Å; L318-F321 PolarHBondContact O-N 2.81Å; L318-I322 HydrophobicContact CD1-CD1 4.23Å; L318-I322 HydrophobicContact CG-CD1 4.29Å; L318-I322 WeakPolarHBondContact O-CG1 3.46Å; L318-I322 PolarHBondContact O-N 3.4Å; L318-I322 VanDerWaalsContact O-N 3.11Å
319	A	95.1	Very high	96.2	Very high	40 Å²	40	32.7 Å²	32.7	33%	0.331	18%	0.177	S	C	.	.	H	α-helix	trans	-61.3	-45.9	176.7	0	0	0	0	0	111.5	V315 S316 I322 M323	V315-A319 WeakPolarHBondContact O-CB 3.41Å; V315-A319 PolarHBondContact O-N 3.07Å; S316-A319 PolarHBondContact O-N 3.36Å; A319-I322 PolarHBondContact O-N 2.97Å; A319-M323 PolarHBondContact O-N 3.08Å
320	M	95.3	Very high	96.3	Very high	3 Å²	3	34.6 Å²	34.6	2%	0.015	19%	0.185	C	C	.	.	H	α-helix	trans	-69.7	-37.7	179.1	-63.7	-55.6	96.4	0	0	112.2	S79 I82 M83 L222 S316 I322 M323 Y324	S79-M320 VanDerWaalsContact O-SD 3.42Å; I82-M320 HydrophobicContact CB-CB 4.47Å; I82-M320 HydrophobicContact CB-CG 3.96Å; I82-M320 HydrophobicContact CD1-CG 4.36Å; I82-M320 HydrophobicContact CG2-CB 3.7Å; I82-M320 HydrophobicContact CG2-CG 3.73Å; M83-M320 HydrophobicContact CB-SD 3.72Å; M83-M320 HydrophobicContact CG-SD 4.19Å; M83-M320 HydrophobicContact SD-SD 4.25Å; L222-M320 HydrophobicContact CD1-CE 4.11Å; S316-M320 WeakPolarHBondContact O-CB 3.46Å; S316-M320 VanDerWaalsContact O-CG 3.27Å; S316-M320 WeakPolarHBondContact O-CG 3.2Å; S316-M320 PolarHBondContact O-N 3.05Å; M320-I322 VanDerWaalsContact C-N 3.3Å; M320-I322 PolarHBondContact O-N 3.48Å; M320-M323 HydrophobicContact CE-CG 4.38Å; M320-M323 HydrophobicContact CE-SD 3.44Å; M320-M323 WeakPolarHBondContact CE-SD 3.26Å; M320-M323 PolarHBondContact O-N 3.23Å; M320-M323 HydrophobicContact SD-SD 4.29Å; M320-Y324 WeakPolarHBondContact O-CB 3.38Å; M320-Y324 WeakPolarHBondContact O-CD1 3.27Å; M320-Y324 PolarHBondContact O-N 3.17Å
321	F	96.7	Very high	96.3	Very high	42 Å²	42	33.2 Å²	33.2	18%	0.184	18%	0.179	C	C	.	.	H	α-helix	trans	-56.3	-43.6	172.1	173.4	-90.4	0	0	0	111.8	L106 V107 A110 F317 L318 L325	L106-F321 HydrophobicContact CB-CE2 4.32Å; L106-F321 HydrophobicContact CD2-CD2 3.78Å; L106-F321 HydrophobicContact CD2-CE2 3.46Å; L106-F321 VanDerWaalsContact CD2-CE2 3.46Å; L106-F321 HydrophobicContact CD2-CZ 4.06Å; L106-F321 HydrophobicContact CG-CD2 3.81Å; L106-F321 HydrophobicContact CG-CE2 3.66Å; V107-F321 HydrophobicContact CB-CE2 4.34Å; V107-F321 HydrophobicContact CG2-CE2 3.51Å; V107-F321 HydrophobicContact CG2-CZ 3.55Å; A110-F321 HydrophobicContact CB-CD2 4.16Å; F317-F321 WeakPolarHBondContact O-CB 3.12Å; F317-F321 PolarHBondContact O-N 2.86Å; L318-F321 PolarHBondContact O-N 2.81Å; F321-L325 HydrophobicContact CE1-CD2 4.15Å; F321-L325 HydrophobicContact CZ-CD2 4.33Å; F321-L325 VanDerWaalsContact O-CB 3.25Å; F321-L325 WeakPolarHBondContact O-CB 3.28Å; F321-L325 PolarHBondContact O-N 2.89Å
322	I	96.8	Very high	96.2	Very high	83 Å²	83	29.1 Å²	29.1	43%	0.426	16%	0.157	S	C	.	.	H	α-helix	trans	-65.9	-48.5	177.1	-66.8	165.4	0	0	0	110.8	L318 A319 M320 Y324 L325 L326	L318-I322 HydrophobicContact CD1-CD1 4.23Å; L318-I322 HydrophobicContact CG-CD1 4.29Å; L318-I322 WeakPolarHBondContact O-CG1 3.46Å; L318-I322 PolarHBondContact O-N 3.4Å; L318-I322 VanDerWaalsContact O-N 3.11Å; A319-I322 PolarHBondContact O-N 2.97Å; M320-I322 VanDerWaalsContact C-N 3.3Å; M320-I322 PolarHBondContact O-N 3.48Å; I322-Y324 VanDerWaalsContact C-N 3.32Å; I322-Y324 PolarHBondContact O-N 3.36Å; I322-L325 PolarHBondContact O-N 2.99Å; I322-L326 HydrophobicContact CG2-CD1 3.79Å; I322-L326 HydrophobicContact CG2-CG 4.49Å; I322-L326 WeakPolarHBondContact O-CB 3.39Å; I322-L326 VanDerWaalsContact O-CG 3.27Å; I322-L326 WeakPolarHBondContact O-CG 3.28Å; I322-L326 PolarHBondContact O-N 3.31Å
323	M	95.6	Very high	96.1	Very high	16 Å²	16	31.2 Å²	31.2	8%	0.079	17%	0.168	C	C	.	.	H	α-helix	trans	-60	-42.3	177.5	-74	-176.5	60.3	0	0	112.3	M83 L222 M225 V226 L229 A319 M320 A327	M83-M323 HydrophobicContact SD-CE 3.88Å; L222-M323 HydrophobicContact CD1-CE 4.47Å; L222-M323 HydrophobicContact CD1-SD 4.23Å; M225-M323 HydrophobicContact CB-CE 4.22Å; V226-M323 HydrophobicContact CG2-CE 3.96Å; V226-M323 HydrophobicContact CG2-SD 4.08Å; L229-M323 HydrophobicContact CD2-CB 4.2Å; L229-M323 HydrophobicContact CD2-CG 3.91Å; A319-M323 PolarHBondContact O-N 3.08Å; M320-M323 HydrophobicContact CE-CG 4.38Å; M320-M323 HydrophobicContact CE-SD 3.44Å; M320-M323 WeakPolarHBondContact CE-SD 3.26Å; M320-M323 PolarHBondContact O-N 3.23Å; M320-M323 HydrophobicContact SD-SD 4.29Å; M323-A327 WeakPolarHBondContact O-CB 3.28Å; M323-A327 PolarHBondContact O-N 3.17Å
324	Y	97.3	Very high	95.8	Very high	0 Å²	0	31.2 Å²	31.2	0%	0	17%	0.168	C	C	.	.	H	α-helix	trans	-65.4	-47	178.4	-76.8	2	0	0	0	112.6	I82 M83 I87 L90 L106 A287 F288 M320 I322 L326 A328	I82-Y324 VanDerWaalsContact C-OH 3.3Å; I82-Y324 HydrophobicContact CG2-CE2 4.24Å; I82-Y324 PolarHBondContact O-OH 2.9Å; M83-Y324 WeakPolarHBondContact CA-OH 3.07Å; M83-Y324 PolarHBondContact N-OH 3.38Å; M83-Y324 PolarHBondContact O-OH 3.25Å; I87-Y324 HydrophobicContact CB-CD1 4.28Å; I87-Y324 HydrophobicContact CB-CE1 3.97Å; I87-Y324 HydrophobicContact CD1-CD1 4.3Å; I87-Y324 HydrophobicContact CG1-CD1 4.1Å; I87-Y324 HydrophobicContact CG1-CE1 4.28Å; L90-Y324 VanDerWaalsContact CD1-CB 3.46Å; L90-Y324 HydrophobicContact CD1-CD1 3.59Å; L90-Y324 HydrophobicContact CD1-CD2 3.79Å; L90-Y324 HydrophobicContact CD1-CE1 4.17Å; L90-Y324 HydrophobicContact CD1-CE2 4.37Å; L90-Y324 HydrophobicContact CD1-CG 3.34Å; L106-Y324 HydrophobicContact CD1-CD2 4.34Å; A287-Y324 HydrophobicContact CB-CE2 3.81Å; A287-Y324 VanDerWaalsContact O-CE2 3.23Å; A287-Y324 WeakPolarHBondContact O-CE2 3.41Å; A287-Y324 PolarHBondContact O-OH 3.36Å; F288-Y324 HydrophobicContact CD1-CD2 4.48Å; F288-Y324 HydrophobicContact CD1-CE2 4.03Å; F288-Y324 AromaticContact CE1-CD2 3.79Å; F288-Y324 HydrophobicContact CE1-CD2 3.79Å; F288-Y324 AromaticContact CE1-CE2 3.76Å; F288-Y324 HydrophobicContact CE1-CE2 3.76Å; F288-Y324 HydrophobicContact CE2-CD2 4.08Å; F288-Y324 HydrophobicContact CE2-CE2 4.32Å; F288-Y324 HydrophobicContact CG-CE2 4.42Å; F288-Y324 AromaticContact CZ-CD2 3.56Å; F288-Y324 HydrophobicContact CZ-CD2 3.56Å; F288-Y324 AromaticContact CZ-CE2 3.93Å; F288-Y324 HydrophobicContact CZ-CE2 3.93Å; M320-Y324 WeakPolarHBondContact O-CB 3.38Å; M320-Y324 WeakPolarHBondContact O-CD1 3.27Å; M320-Y324 PolarHBondContact O-N 3.17Å; I322-Y324 VanDerWaalsContact C-N 3.32Å; I322-Y324 PolarHBondContact O-N 3.36Å; Y324-L326 VanDerWaalsContact C-N 3.33Å; Y324-L326 PolarHBondContact O-N 3.03Å; Y324-A328 WeakPolarHBondContact O-CB 3.39Å; Y324-A328 PolarHBondContact O-N 3.48Å
325	L	97.6	Very high	95.5	Very high	42 Å²	42	27.9 Å²	27.9	22%	0.22	15%	0.15	C	C	.	.	H	α-helix	trans	-59.6	-46.3	177.3	177.8	57.2	0	0	0	110.9	V103 L106 F321 I322 L329	V103-L325 HydrophobicContact CG2-CD1 3.78Å; L106-L325 HydrophobicContact CD2-CB 3.8Å; L106-L325 HydrophobicContact CD2-CD1 4.15Å; F321-L325 HydrophobicContact CE1-CD2 4.15Å; F321-L325 HydrophobicContact CZ-CD2 4.33Å; F321-L325 VanDerWaalsContact O-CB 3.25Å; F321-L325 WeakPolarHBondContact O-CB 3.28Å; F321-L325 PolarHBondContact O-N 2.89Å; I322-L325 PolarHBondContact O-N 2.99Å; L325-L329 WeakPolarHBondContact O-CB 3.17Å; L325-L329 PolarHBondContact O-N 2.92Å
326	L	97.4	Very high	95.1	Very high	57 Å²	57	25.1 Å²	25.1	30%	0.298	13%	0.133	S	C	.	.	H	α-helix	trans	-69.4	-46.4	-179.7	-64.1	170.2	0	0	0	111.8	L229 I322 Y324 A328 L329 F330	L229-L326 HydrophobicContact CD1-CB 3.69Å; L229-L326 HydrophobicContact CD2-CB 4.48Å; L229-L326 HydrophobicContact CD2-CD1 4.46Å; I322-L326 HydrophobicContact CG2-CD1 3.79Å; I322-L326 HydrophobicContact CG2-CG 4.49Å; I322-L326 WeakPolarHBondContact O-CB 3.39Å; I322-L326 VanDerWaalsContact O-CG 3.27Å; I322-L326 WeakPolarHBondContact O-CG 3.28Å; I322-L326 PolarHBondContact O-N 3.31Å; Y324-L326 VanDerWaalsContact C-N 3.33Å; Y324-L326 PolarHBondContact O-N 3.03Å; L326-A328 PolarHBondContact O-N 3.14Å; L326-L329 PolarHBondContact O-N 3.49Å; L326-F330 HydrophobicContact CB-CD2 4.47Å; L326-F330 HydrophobicContact CD2-CD2 4.37Å; L326-F330 HydrophobicContact CD2-CE2 3.92Å; L326-F330 WeakPolarHBondContact O-CB 3.46Å; L326-F330 WeakPolarHBondContact O-CD2 3.22Å; L326-F330 PolarHBondContact O-N 2.83Å
327	A	96.2	Very high	94.6	Very high	1 Å²	1	29.5 Å²	29.5	1%	0.008	16%	0.156	C	C	.	.	H	α-helix	trans	-61.5	-43	178.1	0	0	0	0	0	112	I87 F228 L229 M323 G331	I87-A327 HydrophobicContact CD1-CB 3.95Å; I87-A327 HydrophobicContact CG1-CB 3.82Å; F228-A327 HydrophobicContact CE1-CB 4.49Å; L229-A327 HydrophobicContact CD1-CB 4.02Å; M323-A327 WeakPolarHBondContact O-CB 3.28Å; M323-A327 PolarHBondContact O-N 3.17Å; A327-G331 WeakPolarHBondContact O-CA 3.5Å; A327-G331 PolarHBondContact O-N 3.41Å
328	A	96.9	Very high	94.1	Very high	0 Å²	0	33.4 Å²	33.4	0%	0	17%	0.174	C	C	.	.	H	α-helix	trans	-65.1	-46.4	176.3	0	0	0	0	0	111.8	L90 M94 F102 Y324 L326 Y332	L90-A328 HydrophobicContact CB-CB 3.83Å; M94-A328 HydrophobicContact CE-CB 3.8Å; F102-A328 HydrophobicContact CD1-CB 4.41Å; F102-A328 HydrophobicContact CE1-CB 3.52Å; F102-A328 HydrophobicContact CE2-CB 4.4Å; F102-A328 HydrophobicContact CZ-CB 3.52Å; Y324-A328 WeakPolarHBondContact O-CB 3.39Å; Y324-A328 PolarHBondContact O-N 3.48Å; L326-A328 PolarHBondContact O-N 3.14Å; A328-Y332 WeakPolarHBondContact O-CB 3.48Å; A328-Y332 PolarHBondContact O-N 3.34Å
329	L	96.4	Very high	93.8	Very high	43 Å²	43	28.8 Å²	28.8	23%	0.225	15%	0.15	C	C	.	.	H	α-helix	trans	-67.1	-51.6	-177.1	-177.2	64	0	0	0	112.4	M94 I99 L325 L326 Y332 L333	M94-L329 HydrophobicContact CE-CB 4.1Å; M94-L329 HydrophobicContact CE-CD1 4.34Å; M94-L329 HydrophobicContact SD-CB 4.47Å; M94-L329 HydrophobicContact SD-CD1 4.13Å; I99-L329 HydrophobicContact CD1-CD1 4.1Å; I99-L329 HydrophobicContact CG2-CD1 4.2Å; L325-L329 WeakPolarHBondContact O-CB 3.17Å; L325-L329 PolarHBondContact O-N 2.92Å; L326-L329 PolarHBondContact O-N 3.49Å; L329-Y332 PolarHBondContact O-N 2.8Å; L329-L333 HydrophobicContact CD1-CD1 3.79Å; L329-L333 HydrophobicContact CD1-CG 4.17Å; L329-L333 HydrophobicContact CG-CD1 3.9Å; L329-L333 WeakPolarHBondContact O-CB 3.12Å; L329-L333 VanDerWaalsContact O-CG 3.23Å; L329-L333 WeakPolarHBondContact O-CG 3.26Å; L329-L333 PolarHBondContact O-N 3.4Å
330	F	95.8	Very high	93.6	Very high	39 Å²	39	27.7 Å²	27.7	17%	0.171	14%	0.143	C	C	.	.	H	α-helix	trans	-71.3	-33.4	-179.7	-76.1	-87.8	0	0	0	111.7	V232 I233 K236 F237 L326 T334	V232-F330 HydrophobicContact CG1-CB 3.85Å; I233-F330 HydrophobicContact CB-CD1 4.35Å; I233-F330 HydrophobicContact CB-CG 4.4Å; I233-F330 HydrophobicContact CG1-CB 4.26Å; I233-F330 HydrophobicContact CG1-CD1 4.23Å; I233-F330 HydrophobicContact CG1-CD2 3.79Å; I233-F330 HydrophobicContact CG1-CE2 4.18Å; I233-F330 HydrophobicContact CG1-CG 3.83Å; I233-F330 HydrophobicContact CG2-CD1 4.24Å; I233-F330 HydrophobicContact CG2-CE1 4.09Å; I233-F330 HydrophobicContact CG2-CZ 4.38Å; K236-F330 HydrophobicContact CB-CD1 3.8Å; K236-F330 HydrophobicContact CG-CD1 3.89Å; K236-F330 HydrophobicContact CG-CE1 4.48Å; F237-F330 AromaticContact CE2-CE1 3.9Å; F237-F330 HydrophobicContact CE2-CE1 3.9Å; F237-F330 HydrophobicContact CZ-CE1 4.01Å; L326-F330 HydrophobicContact CB-CD2 4.47Å; L326-F330 HydrophobicContact CD2-CD2 4.37Å; L326-F330 HydrophobicContact CD2-CE2 3.92Å; L326-F330 WeakPolarHBondContact O-CB 3.46Å; L326-F330 WeakPolarHBondContact O-CD2 3.22Å; L326-F330 PolarHBondContact O-N 2.83Å; F330-T334 WeakPolarHBondContact O-CB 3.39Å; F330-T334 PolarHBondContact O-N 3.23Å; F330-T334 PolarHBondContact O-OG1 3.12Å
331	G	94.8	Very high	93.4	Very high	0 Å²	0	29.3 Å²	29.3	0%	0	15%	0.153	C	C	.	.	H	α-helix	trans	-65.4	-43.8	171.2	0	0	0	0	0	112.9	A327 T334	A327-G331 WeakPolarHBondContact O-CA 3.5Å; A327-G331 PolarHBondContact O-N 3.41Å; G331-T334 PolarHBondContact O-N 2.95Å
332	Y	94.9	Very high	93.2	Very high	1 Å²	1	27.7 Å²	27.7	0%	0.004	15%	0.147	C	C	.	.	H	α-helix	trans	-62	-56	174.1	171.5	-115.8	0	0	0	111.3	M94 A95 I99 P268 K269 A328 L329 T334 F335 N336 V339	M94-Y332 HydrophobicContact CB-CG 4.5Å; M94-Y332 HydrophobicContact CG-CD1 4.08Å; M94-Y332 HydrophobicContact CG-CG 3.95Å; M94-Y332 VanDerWaalsContact SD-CB 3.55Å; M94-Y332 HydrophobicContact SD-CD1 3.68Å; M94-Y332 HydrophobicContact SD-CG 3.81Å; A95-Y332 HydrophobicContact CB-CD2 3.79Å; A95-Y332 HydrophobicContact CB-CE2 4.02Å; I99-Y332 HydrophobicContact CD1-CD1 4.1Å; I99-Y332 HydrophobicContact CD1-CE1 3.84Å; I99-Y332 HydrophobicContact CG1-CD1 3.82Å; I99-Y332 HydrophobicContact CG1-CE1 3.58Å; P268-Y332 HydrophobicContact CB-CE1 4.35Å; K269-Y332 PolarHBondContact N-OH 3.26Å; A328-Y332 WeakPolarHBondContact O-CB 3.48Å; A328-Y332 PolarHBondContact O-N 3.34Å; L329-Y332 PolarHBondContact O-N 2.8Å; Y332-T334 PolarHBondContact O-N 3.28Å; Y332-F335 PolarHBondContact O-N 3.38Å; Y332-N336 WeakPolarHBondContact CD2-O 3.47Å; Y332-N336 HydrophobicContact CE2-CB 4.47Å; Y332-N336 VanDerWaalsContact CE2-O 3.3Å; Y332-N336 WeakPolarHBondContact CE2-O 3.38Å; Y332-N336 WeakPolarHBondContact O-CA 3.27Å; Y332-N336 PolarHBondContact O-N 3.45Å; Y332-V339 HydrophobicContact CD2-CG2 4.39Å
333	L	92.6	Very high	93	Very high	44 Å²	44	23.8 Å²	23.8	23%	0.23	13%	0.127	C	C	.	.	H	α-helix	trans	-62.9	-10.8	-178.3	-66.9	173.4	0	0	0	113.8	I99 K236 P268 L329	I99-L333 HydrophobicContact CD1-CD2 4.26Å; K236-L333 HydrophobicContact CD-CB 3.67Å; K236-L333 WeakPolarHBondContact CD-O 3.43Å; K236-L333 WeakPolarHBondContact CE-O 3.45Å; K236-L333 PolarHBondContact NZ-O 2.65Å; P268-L333 HydrophobicContact CB-CD2 3.76Å; L329-L333 HydrophobicContact CD1-CD1 3.79Å; L329-L333 HydrophobicContact CD1-CG 4.17Å; L329-L333 HydrophobicContact CG-CD1 3.9Å; L329-L333 WeakPolarHBondContact O-CB 3.12Å; L329-L333 VanDerWaalsContact O-CG 3.23Å; L329-L333 WeakPolarHBondContact O-CG 3.26Å; L329-L333 PolarHBondContact O-N 3.4Å
334	T	91	Very high	92.7	Very high	0 Å²	0	23 Å²	23	0%	0	12%	0.123	C	C	.	.	H	α-helix	trans	-80.7	-35.6	173.7	-61.3	0	0	0	0	112.7	K236 I239 F330 G331 Y332 Y347	K236-T334 WeakPolarHBondContact CA-OG1 3.38Å; I239-T334 HydrophobicContact CB-CG2 4.25Å; I239-T334 HydrophobicContact CD1-CG2 3.72Å; I239-T334 HydrophobicContact CG2-CG2 4.29Å; F330-T334 WeakPolarHBondContact O-CB 3.39Å; F330-T334 PolarHBondContact O-N 3.23Å; F330-T334 PolarHBondContact O-OG1 3.12Å; G331-T334 PolarHBondContact O-N 2.95Å; Y332-T334 PolarHBondContact O-N 3.28Å; T334-Y347 HydrophobicContact CG2-CE1 3.87Å
335	F	89.1	Confident	92.3	Very high	2 Å²	2	27 Å²	27	1%	0.009	14%	0.141	C	C	.	.	H	α-helix	trans	-124.2	-10.3	-174	-57.4	-74.5	0	0	0	114.4	L243 Y332 I337 H338 V339 L343 T346 Y347 Y350	L243-F335 HydrophobicContact CD1-CD1 3.99Å; L243-F335 HydrophobicContact CD2-CD1 3.83Å; L243-F335 HydrophobicContact CD2-CE1 4.18Å; Y332-F335 PolarHBondContact O-N 3.38Å; F335-I337 PolarHBondContact O-N 3.28Å; F335-I337 VanDerWaalsContact O-N 3.09Å; F335-H338 HydrophobicContact CB-CB 4.3Å; F335-H338 WeakPolarHBondContact O-CB 3.48Å; F335-H338 PolarHBondContact O-N 3.01Å; F335-H338 PolarHBondContact O-ND1 3.29Å; F335-V339 HydrophobicContact CB-CG2 3.81Å; F335-L343 HydrophobicContact CD2-CD1 4.07Å; F335-L343 HydrophobicContact CE2-CD1 3.89Å; F335-T346 HydrophobicContact CD1-CG2 4.07Å; F335-T346 HydrophobicContact CD2-CG2 3.75Å; F335-T346 HydrophobicContact CE1-CG2 4.14Å; F335-T346 HydrophobicContact CE2-CG2 3.82Å; F335-T346 HydrophobicContact CG-CG2 3.88Å; F335-T346 HydrophobicContact CZ-CG2 4.01Å; F335-Y347 AromaticContact CE2-CD1 3.98Å; F335-Y347 HydrophobicContact CE2-CD1 3.98Å; F335-Y347 HydrophobicContact CE2-CD2 4.22Å; F335-Y347 AromaticContact CE2-CE1 3.78Å; F335-Y347 HydrophobicContact CE2-CE1 3.78Å; F335-Y347 HydrophobicContact CE2-CE2 4.05Å; F335-Y347 HydrophobicContact CE2-CG 4.16Å; F335-Y347 AromaticContact CE2-CZ 3.8Å; F335-Y347 AromaticContact CZ-CD1 3.53Å; F335-Y347 HydrophobicContact CZ-CD1 3.53Å; F335-Y347 HydrophobicContact CZ-CD2 4.42Å; F335-Y347 AromaticContact CZ-CE1 3.68Å; F335-Y347 HydrophobicContact CZ-CE1 3.68Å; F335-Y347 AromaticContact CZ-CG 3.9Å; F335-Y347 HydrophobicContact CZ-CG 3.9Å; F335-Y350 HydrophobicContact CD1-CD2 4.13Å; F335-Y350 HydrophobicContact CD1-CE2 4.06Å; F335-Y350 AromaticContact CE1-CD2 3.67Å; F335-Y350 HydrophobicContact CE1-CD2 3.67Å; F335-Y350 HydrophobicContact CE1-CE2 4.07Å; F335-Y350 HydrophobicContact CE1-CG 4.43Å
336	N	89.4	Confident	91.9	Very high	4 Å²	4	25.5 Å²	25.5	2%	0.021	13%	0.133	C	C	.	.	G	3₁₀ helix	trans	46.2	-106.5	-173.6	-65.8	-45.9	0	0	0	112.7	T265 C266 Y332 H338 V339	T265-N336 VanDerWaalsContact O-CB 3.3Å; T265-N336 WeakPolarHBondContact O-CB 3.34Å; T265-N336 PolarHBondContact O-ND2 2.82Å; C266-N336 VanDerWaalsContact C-ND2 3.34Å; C266-N336 WeakPolarHBondContact CA-ND2 3.48Å; C266-N336 PolarHBondContact O-ND2 2.88Å; Y332-N336 WeakPolarHBondContact CD2-O 3.47Å; Y332-N336 HydrophobicContact CE2-CB 4.47Å; Y332-N336 VanDerWaalsContact CE2-O 3.3Å; Y332-N336 WeakPolarHBondContact CE2-O 3.38Å; Y332-N336 WeakPolarHBondContact O-CA 3.27Å; Y332-N336 PolarHBondContact O-N 3.45Å; N336-H338 VanDerWaalsContact C-N 3.27Å; N336-H338 PolarHBondContact O-N 3.3Å; N336-V339 WeakPolarHBondContact O-CG2 3.48Å
337	I	84.2	Confident	91.4	Very high	91 Å²	91	22.9 Å²	22.9	47%	0.467	12%	0.12	S	C	.	.	G	3₁₀ helix	trans	-75	-13.9	-179.8	63.4	175.1	0	0	0	113.6	T265 F335	T265-I337 HydrophobicContact CG2-CD1 4.06Å; F335-I337 PolarHBondContact O-N 3.28Å; F335-I337 VanDerWaalsContact O-N 3.09Å
338	H	86.8	Confident	90.8	Very high	86 Å²	86	23.2 Å²	23.2	40%	0.398	12%	0.122	S	C	.	.	G	3₁₀ helix	trans	-94.7	10	-174.5	-55.1	104.5	0	0	0	114.2	L243 F335 N336 G340	L243-H338 HydrophobicContact CD1-CB 4.09Å; F335-H338 HydrophobicContact CB-CB 4.3Å; F335-H338 WeakPolarHBondContact O-CB 3.48Å; F335-H338 PolarHBondContact O-N 3.01Å; F335-H338 PolarHBondContact O-ND1 3.29Å; N336-H338 VanDerWaalsContact C-N 3.27Å; N336-H338 PolarHBondContact O-N 3.3Å; H338-G340 PolarHBondContact O-N 3.37Å
339	V	91	Very high	90.1	Very high	10 Å²	10	31.7 Å²	31.7	6%	0.061	15%	0.154	C	C	.	.			trans	-65.3	116.6	177.5	-177.7	0	0	0	0	110.1	S91 F92 A95 Y332 F335 N336	S91-V339 WeakPolarHBondContact OG-CG1 3.42Å; F92-V339 HydrophobicContact CB-CG1 4.18Å; A95-V339 HydrophobicContact CB-CB 3.98Å; A95-V339 HydrophobicContact CB-CG2 4.11Å; Y332-V339 HydrophobicContact CD2-CG2 4.39Å; F335-V339 HydrophobicContact CB-CG2 3.81Å; N336-V339 WeakPolarHBondContact O-CG2 3.48Å
340	G	90.8	Very high	89.2	Confident	18 Å²	18	31.9 Å²	31.9	19%	0.186	15%	0.152	C	C	.	.			trans	-74.2	165	172	0	0	0	0	0	112.6	H338 E342 T346	H338-G340 PolarHBondContact O-N 3.37Å; G340-E342 PolarHBondContact O-N 3Å; G340-T346 VanDerWaalsContact CA-OG1 3.29Å; G340-T346 WeakPolarHBondContact CA-OG1 3.22Å; G340-T346 PolarHBondContact N-OG1 3.04Å
341	P	90.4	Very high	88.4	Confident	36 Å²	36	33 Å²	33	23%	0.234	16%	0.156	C	C	.	.	S	Bend	trans	-66.3	-4.5	-177.9	29.2	-36.9	0	0	0	114.9	F92 I419 R420	F92-P341 HydrophobicContact CD1-CB 4.48Å; F92-P341 HydrophobicContact CD2-CB 4.1Å; F92-P341 HydrophobicContact CE2-CB 4.17Å; F92-P341 HydrophobicContact CG-CB 4.25Å; F92-P341 HydrophobicContact CZ-CB 4.41Å; P341-I419 HydrophobicContact CB-CG2 4.21Å; P341-I419 VanDerWaalsContact O-CG2 3.24Å; P341-I419 WeakPolarHBondContact O-CG2 3.47Å; P341-R420 HydrophobicContact CB-CB 3.89Å
342	E	92	Very high	87.2	Confident	9 Å²	9	38.8 Å²	38.8	4%	0.042	18%	0.177	C	C	.	.	S	Bend	trans	-138.9	118.7	173.7	-159.2	-70.1	100.4	0	0	107	L88 G340 L344 H345 T346 I419	L88-E342 HydrophobicContact CB-CG 4.48Å; G340-E342 PolarHBondContact O-N 3Å; E342-L344 WeakPolarHBondContact OE1-CB 3.24Å; E342-L344 PolarHBondContact OE1-N 2.92Å; E342-L344 PolarHBondContact OE2-N 3.05Å; E342-H345 WeakPolarHBondContact OE2-CB 3.23Å; E342-H345 PolarHBondContact OE2-N 3.33Å; E342-T346 PolarHBondContact O-N 3.47Å; E342-T346 PolarHBondContact O-OG1 3.13Å; E342-I419 HydrophobicContact CB-CG2 4.07Å; E342-I419 HydrophobicContact CG-CD1 4.45Å
343	L	92.4	Very high	86.1	Confident	1 Å²	1	44.7 Å²	44.7	1%	0.005	21%	0.209	C	C	.	.	H	α-helix	trans	-70	-32.8	-170	-177	57	0	0	0	113.5	L88 F228 V232 F335 T346 Y347	L88-L343 PolarHBondContact O-N 3.49Å; L88-L343 VanDerWaalsContact O-N 3.16Å; F228-L343 HydrophobicContact CZ-CD2 4.13Å; V232-L343 HydrophobicContact CG1-CD2 4.4Å; V232-L343 HydrophobicContact CG2-CD2 4.17Å; F335-L343 HydrophobicContact CD2-CD1 4.07Å; F335-L343 HydrophobicContact CE2-CD1 3.89Å; L343-T346 VanDerWaalsContact O-CB 3.3Å; L343-T346 WeakPolarHBondContact O-CB 3.38Å; L343-T346 PolarHBondContact O-N 3.46Å; L343-Y347 HydrophobicContact CD1-CD2 4.27Å; L343-Y347 HydrophobicContact CD1-CE2 3.81Å; L343-Y347 HydrophobicContact CD2-CE2 4.25Å; L343-Y347 HydrophobicContact CG-CD2 4.17Å; L343-Y347 HydrophobicContact CG-CE2 3.76Å; L343-Y347 VanDerWaalsContact O-CD2 3.24Å; L343-Y347 WeakPolarHBondContact O-CD2 3.47Å; L343-Y347 PolarHBondContact O-N 3.3Å
344	L	89.7	Confident	85.8	Confident	0 Å²	0	44.7 Å²	44.7	0%	0	21%	0.209	C	C	.	.	H	α-helix	trans	-74.2	-44.3	-174.7	-158.8	62.6	0	0	0	111.6	E170 F228 E342 T346 Y347 S348 L357 V360 R361 V364	E170-L344 HydrophobicContact CG-CD2 4.14Å; F228-L344 HydrophobicContact CD2-CD1 4.39Å; F228-L344 HydrophobicContact CE2-CD1 4.24Å; E342-L344 WeakPolarHBondContact OE1-CB 3.24Å; E342-L344 PolarHBondContact OE1-N 2.92Å; E342-L344 PolarHBondContact OE2-N 3.05Å; L344-T346 PolarHBondContact O-N 2.91Å; L344-Y347 WeakPolarHBondContact O-CB 3.26Å; L344-Y347 PolarHBondContact O-N 3.08Å; L344-S348 PolarHBondContact O-N 2.64Å; L344-L357 HydrophobicContact CD1-CD1 3.55Å; L344-L357 HydrophobicContact CG-CD1 4.37Å; L344-V360 HydrophobicContact CD1-CG1 4.11Å; L344-R361 HydrophobicContact CD1-CG 4.5Å; L344-R361 HydrophobicContact CD2-CB 4.47Å; L344-R361 HydrophobicContact CD2-CG 4.03Å; L344-R361 HydrophobicContact CG-CG 4.19Å; L344-V364 HydrophobicContact CD2-CB 4.21Å; L344-V364 HydrophobicContact CD2-CG1 4.28Å; L344-V364 HydrophobicContact CD2-CG2 4.33Å
345	H	88.7	Confident	85.7	Confident	84 Å²	84	50.8 Å²	50.8	39%	0.389	24%	0.241	S	C	.	.	H	α-helix	trans	-61.7	-28.6	167.3	-174.1	-71.1	0	0	0	112	E170 E342 S348 R349	E170-H345 WeakPolarHBondContact OE1-CA 3.5Å; E170-H345 PolarHBondContact OE1-N 2.89Å; E342-H345 WeakPolarHBondContact OE2-CB 3.23Å; E342-H345 PolarHBondContact OE2-N 3.33Å; H345-S348 WeakPolarHBondContact O-CB 3.44Å; H345-S348 PolarHBondContact O-N 3.38Å; H345-R349 PolarHBondContact O-N 3.48Å
346	T	89.1	Confident	85.7	Confident	9 Å²	9	53.1 Å²	53.1	6%	0.055	25%	0.253	C	S	.	.	H	α-helix	trans	-65.7	-47.6	172.8	-55.8	0	0	0	0	111.1	F335 G340 E342 L343 L344 S348 R349 Y350	F335-T346 HydrophobicContact CD1-CG2 4.07Å; F335-T346 HydrophobicContact CD2-CG2 3.75Å; F335-T346 HydrophobicContact CE1-CG2 4.14Å; F335-T346 HydrophobicContact CE2-CG2 3.82Å; F335-T346 HydrophobicContact CG-CG2 3.88Å; F335-T346 HydrophobicContact CZ-CG2 4.01Å; G340-T346 VanDerWaalsContact CA-OG1 3.29Å; G340-T346 WeakPolarHBondContact CA-OG1 3.22Å; G340-T346 PolarHBondContact N-OG1 3.04Å; E342-T346 PolarHBondContact O-N 3.47Å; E342-T346 PolarHBondContact O-OG1 3.13Å; L343-T346 VanDerWaalsContact O-CB 3.3Å; L343-T346 WeakPolarHBondContact O-CB 3.38Å; L343-T346 PolarHBondContact O-N 3.46Å; L344-T346 PolarHBondContact O-N 2.91Å; T346-S348 VanDerWaalsContact C-N 3.25Å; T346-S348 PolarHBondContact O-N 2.93Å; T346-R349 WeakPolarHBondContact O-CB 3.3Å; T346-R349 PolarHBondContact O-N 3.44Å; T346-R349 VanDerWaalsContact O-N 3.15Å; T346-Y350 WeakPolarHBondContact O-CD2 3.37Å
347	Y	88.4	Confident	85.7	Confident	2 Å²	2	53 Å²	53	1%	0.008	25%	0.252	C	S	.	.	H	α-helix	trans	-56	-42.1	169.7	-76.2	-75.1	0	0	0	111.7	M231 V232 K235 I239 T334 F335 L343 L344 R349 Y350 Y351 L357	M231-Y347 HydrophobicContact CE-CD1 4.36Å; M231-Y347 HydrophobicContact CE-CG 4.35Å; V232-Y347 HydrophobicContact CG2-CE2 4.12Å; K235-Y347 HydrophobicContact CB-CD1 4.45Å; K235-Y347 HydrophobicContact CB-CE1 3.57Å; K235-Y347 HydrophobicContact CG-CD1 4.45Å; K235-Y347 HydrophobicContact CG-CE1 3.99Å; I239-Y347 HydrophobicContact CD1-CD1 3.95Å; I239-Y347 HydrophobicContact CD1-CE1 3.74Å; T334-Y347 HydrophobicContact CG2-CE1 3.87Å; F335-Y347 AromaticContact CE2-CD1 3.98Å; F335-Y347 HydrophobicContact CE2-CD1 3.98Å; F335-Y347 HydrophobicContact CE2-CD2 4.22Å; F335-Y347 AromaticContact CE2-CE1 3.78Å; F335-Y347 HydrophobicContact CE2-CE1 3.78Å; F335-Y347 HydrophobicContact CE2-CE2 4.05Å; F335-Y347 HydrophobicContact CE2-CG 4.16Å; F335-Y347 AromaticContact CE2-CZ 3.8Å; F335-Y347 AromaticContact CZ-CD1 3.53Å; F335-Y347 HydrophobicContact CZ-CD1 3.53Å; F335-Y347 HydrophobicContact CZ-CD2 4.42Å; F335-Y347 AromaticContact CZ-CE1 3.68Å; F335-Y347 HydrophobicContact CZ-CE1 3.68Å; F335-Y347 AromaticContact CZ-CG 3.9Å; F335-Y347 HydrophobicContact CZ-CG 3.9Å; L343-Y347 HydrophobicContact CD1-CD2 4.27Å; L343-Y347 HydrophobicContact CD1-CE2 3.81Å; L343-Y347 HydrophobicContact CD2-CE2 4.25Å; L343-Y347 HydrophobicContact CG-CD2 4.17Å; L343-Y347 HydrophobicContact CG-CE2 3.76Å; L343-Y347 VanDerWaalsContact O-CD2 3.24Å; L343-Y347 WeakPolarHBondContact O-CD2 3.47Å; L343-Y347 PolarHBondContact O-N 3.3Å; L344-Y347 WeakPolarHBondContact O-CB 3.26Å; L344-Y347 PolarHBondContact O-N 3.08Å; Y347-R349 PolarHBondContact O-N 3.16Å; Y347-R349 VanDerWaalsContact O-N 3.12Å; Y347-Y350 PolarHBondContact O-N 3.32Å; Y347-Y350 VanDerWaalsContact O-N 3.17Å; Y347-Y351 PolarHBondContact O-N 2.83Å; Y347-L357 HydrophobicContact CG-CD1 4.43Å
348	S	83.6	Confident	86.1	Confident	9 Å²	9	49.2 Å²	49.2	6%	0.063	23%	0.233	C	C	.	.	H	α-helix	trans	-61.7	-17	179	-163.9	0	0	0	0	115.5	L344 H345 T346 R352 R361	L344-S348 PolarHBondContact O-N 2.64Å; H345-S348 WeakPolarHBondContact O-CB 3.44Å; H345-S348 PolarHBondContact O-N 3.38Å; T346-S348 VanDerWaalsContact C-N 3.25Å; T346-S348 PolarHBondContact O-N 2.93Å; S348-R352 WeakPolarHBondContact O-CG 3.44Å; S348-R361 VanDerWaalsContact CB-NH1 3.28Å; S348-R361 VanDerWaalsContact CB-NH2 3.27Å; S348-R361 PolarHBondContact OG-NH1 2.9Å; S348-R361 PolarHBondContact OG-NH2 3.16Å
349	R	81.1	Confident	86.4	Confident	178 Å²	178	47 Å²	47	67%	0.672	23%	0.23	S	C	*	.	H	α-helix	trans	-79.7	-27.8	178	-171.8	175.5	-176.3	172.4	1.8	112.7	H345 T346 Y347	H345-R349 PolarHBondContact O-N 3.48Å; T346-R349 WeakPolarHBondContact O-CB 3.3Å; T346-R349 PolarHBondContact O-N 3.44Å; T346-R349 VanDerWaalsContact O-N 3.15Å; Y347-R349 PolarHBondContact O-N 3.16Å; Y347-R349 VanDerWaalsContact O-N 3.12Å
350	Y	78.8	Confident	86.4	Confident	47 Å²	47	46.5 Å²	46.5	18%	0.184	23%	0.227	C	C	.	.	H	α-helix	trans	-108.5	-31.2	-175.7	-63.8	-86.1	0	0	0	112.9	L243 F335 T346 Y347	L243-Y350 HydrophobicContact CB-CD1 4.31Å; L243-Y350 HydrophobicContact CB-CE1 3.94Å; L243-Y350 HydrophobicContact CD1-CE1 4.09Å; L243-Y350 HydrophobicContact CD1-CE2 4.37Å; L243-Y350 HydrophobicContact CG-CE1 4.47Å; F335-Y350 HydrophobicContact CD1-CD2 4.13Å; F335-Y350 HydrophobicContact CD1-CE2 4.06Å; F335-Y350 AromaticContact CE1-CD2 3.67Å; F335-Y350 HydrophobicContact CE1-CD2 3.67Å; F335-Y350 HydrophobicContact CE1-CE2 4.07Å; F335-Y350 HydrophobicContact CE1-CG 4.43Å; T346-Y350 WeakPolarHBondContact O-CD2 3.37Å; Y347-Y350 PolarHBondContact O-N 3.32Å; Y347-Y350 VanDerWaalsContact O-N 3.17Å
351	Y	76.9	Confident	86.5	Confident	63 Å²	63	45.7 Å²	45.7	25%	0.247	22%	0.218	C	C	.	.			trans	-136.4	89.5	-176.4	-60.6	-84.3	0	0	0	109.8	I239 P244 Y347 L357	I239-Y351 HydrophobicContact CB-CE2 4.39Å; I239-Y351 HydrophobicContact CD1-CD2 3.86Å; I239-Y351 HydrophobicContact CD1-CE2 3.54Å; I239-Y351 HydrophobicContact CG1-CD2 4.27Å; I239-Y351 HydrophobicContact CG1-CE2 3.58Å; I239-Y351 HydrophobicContact CG2-CE2 4Å; P244-Y351 WeakPolarHBondContact CG-OH 3.12Å; Y347-Y351 PolarHBondContact O-N 2.83Å; Y351-L357 WeakPolarHBondContact O-CD2 3.47Å
352	R	70.9	Confident	86.7	Confident	120 Å²	120	47.7 Å²	47.7	45%	0.453	23%	0.226	S	C	.	.	S	Bend	trans	-72.6	-51.9	179	-88.5	-171.9	170.1	176.7	-3.9	112.5	S348 D354	S348-R352 WeakPolarHBondContact O-CG 3.44Å; R352-D354 VanDerWaalsContact C-N 3.29Å; R352-D354 PolarHBondContact O-N 2.98Å
353	D	72.4	Confident	86.7	Confident	125 Å²	125	47.8 Å²	47.8	67%	0.668	23%	0.229	S	C	*	.	S	Bend	trans	-92.5	15.2	-160.6	-45.5	-69.7	0	0	0	113.8	F177 I355	F177-D353 HydrophobicContact CE2-CB 4.38Å; D353-I355 PolarHBondContact O-N 3Å
354	D	85.3	Confident	86.8	Confident	44 Å²	44	47.8 Å²	47.8	24%	0.235	23%	0.229	C	C	.	.			trans	-76	112.4	-178.5	-169.5	-65.6	0	0	0	111.1	K235 R352 L356 L357 L358	K235-D354 IonicContact NZ-OD1 3.01Å; K235-D354 PolarHBondContact NZ-OD1 3.02Å; K235-D354 IonicContact NZ-OD2 2.59Å; K235-D354 PolarHBondContact NZ-OD2 3.23Å; R352-D354 VanDerWaalsContact C-N 3.29Å; R352-D354 PolarHBondContact O-N 2.98Å; D354-L356 PolarHBondContact O-N 2.85Å; D354-L356 WeakPolarHBondContact OD1-CB 3.22Å; D354-L356 PolarHBondContact OD1-N 3.35Å; D354-L356 VanDerWaalsContact OD1-N 3.1Å; D354-L357 HydrophobicContact CB-CB 4.02Å; D354-L357 WeakPolarHBondContact O-CA 3.4Å; D354-L357 WeakPolarHBondContact O-CB 3.42Å; D354-L357 PolarHBondContact O-N 3.41Å; D354-L357 PolarHBondContact OD1-N 3.1Å; D354-L358 PolarHBondContact O-N 2.81Å
355	I	89	Confident	87	Confident	128 Å²	128	48.4 Å²	48.4	66%	0.656	23%	0.232	S	C	*	.	H	α-helix	trans	-58.9	-32.9	-175.4	-57.8	173.5	0	0	0	112	F177 D353 L358 A359	F177-I355 HydrophobicContact CZ-CG1 4.45Å; D353-I355 PolarHBondContact O-N 3Å; I355-L358 PolarHBondContact O-N 2.89Å; I355-A359 WeakPolarHBondContact O-CB 3.41Å; I355-A359 PolarHBondContact O-N 3.37Å
356	L	89.8	Confident	87.1	Confident	51 Å²	51	46.4 Å²	46.4	27%	0.267	23%	0.23	S	C	.	.	H	α-helix	trans	-71.6	-38.4	177	177.3	62.1	0	0	0	111.1	F227 M231 I234 D354 V360	F227-L356 HydrophobicContact CE2-CD1 4Å; F227-L356 HydrophobicContact CZ-CD1 3.88Å; M231-L356 HydrophobicContact CG-CD2 4.15Å; M231-L356 HydrophobicContact CG-CG 3.93Å; I234-L356 HydrophobicContact CG2-CD2 4.26Å; D354-L356 PolarHBondContact O-N 2.85Å; D354-L356 WeakPolarHBondContact OD1-CB 3.22Å; D354-L356 PolarHBondContact OD1-N 3.35Å; D354-L356 VanDerWaalsContact OD1-N 3.1Å; L356-V360 WeakPolarHBondContact O-CG2 3.43Å; L356-V360 PolarHBondContact O-N 2.92Å; L356-V360 VanDerWaalsContact O-N 3.13Å
357	L	89.1	Confident	87.3	Confident	2 Å²	2	46 Å²	46	1%	0.01	23%	0.227	C	C	.	.	H	α-helix	trans	-63.1	-47	171.3	176.4	64.2	0	0	0	110.9	M231 L344 Y347 Y351 D354 A359 V360 R361	M231-L357 HydrophobicContact CE-CB 3.81Å; M231-L357 HydrophobicContact CE-CD1 3.47Å; M231-L357 VanDerWaalsContact CE-CD1 3.47Å; M231-L357 HydrophobicContact CE-CG 4.2Å; L344-L357 HydrophobicContact CD1-CD1 3.55Å; L344-L357 HydrophobicContact CG-CD1 4.37Å; Y347-L357 HydrophobicContact CG-CD1 4.43Å; Y351-L357 WeakPolarHBondContact O-CD2 3.47Å; D354-L357 HydrophobicContact CB-CB 4.02Å; D354-L357 WeakPolarHBondContact O-CA 3.4Å; D354-L357 WeakPolarHBondContact O-CB 3.42Å; D354-L357 PolarHBondContact O-N 3.41Å; D354-L357 PolarHBondContact OD1-N 3.1Å; L357-A359 VanDerWaalsContact C-N 3.34Å; L357-A359 PolarHBondContact O-N 2.97Å; L357-V360 CarbonylContact O-C 3.53Å; L357-V360 PolarHBondContact O-N 3.44Å; L357-V360 VanDerWaalsContact O-N 3.08Å; L357-R361 HydrophobicContact CD1-CG 4.46Å; L357-R361 HydrophobicContact CG-CG 4.48Å; L357-R361 WeakPolarHBondContact O-CG 3.38Å; L357-R361 PolarHBondContact O-N 3.44Å
358	L	91.4	Very high	87.4	Confident	12 Å²	12	45.9 Å²	45.9	6%	0.063	23%	0.227	C	C	.	.	H	α-helix	trans	-56.2	-46	177.3	-176.4	75.2	0	0	0	112.3	V174 F177 F178 D354 I355 V360 R361 L362	V174-L358 HydrophobicContact CB-CD1 4.37Å; V174-L358 HydrophobicContact CG1-CD1 4.41Å; V174-L358 HydrophobicContact CG2-CD1 4.11Å; F177-L358 HydrophobicContact CB-CD1 4.01Å; F177-L358 HydrophobicContact CD1-CD1 4.32Å; F177-L358 HydrophobicContact CD1-CD2 3.33Å; F177-L358 HydrophobicContact CD1-CG 4.45Å; F177-L358 HydrophobicContact CD2-CD2 4.34Å; F177-L358 HydrophobicContact CE1-CD2 3.44Å; F177-L358 VanDerWaalsContact CE1-CD2 3.44Å; F177-L358 HydrophobicContact CE2-CD2 4.41Å; F177-L358 HydrophobicContact CG-CD1 4.08Å; F177-L358 HydrophobicContact CG-CD2 3.83Å; F177-L358 HydrophobicContact CZ-CD2 4Å; F178-L358 HydrophobicContact CE2-CD2 4.23Å; F178-L358 HydrophobicContact CZ-CD2 4Å; D354-L358 PolarHBondContact O-N 2.81Å; I355-L358 PolarHBondContact O-N 2.89Å; L358-V360 VanDerWaalsContact C-N 3.28Å; L358-V360 PolarHBondContact O-N 3.08Å; L358-R361 PolarHBondContact O-N 2.89Å; L358-L362 PolarHBondContact O-N 2.89Å
359	A	92.8	Very high	87.8	Confident	39 Å²	39	46 Å²	46	32%	0.322	23%	0.227	S	C	.	.	H	α-helix	trans	-60.7	-37.7	176.5	0	0	0	0	0	112.2	F227 I355 L357 A363	F227-A359 HydrophobicContact CE1-CB 4.21Å; F227-A359 HydrophobicContact CZ-CB 4.23Å; I355-A359 WeakPolarHBondContact O-CB 3.41Å; I355-A359 PolarHBondContact O-N 3.37Å; L357-A359 VanDerWaalsContact C-N 3.34Å; L357-A359 PolarHBondContact O-N 2.97Å; A359-A363 PolarHBondContact O-N 2.9Å; A359-A363 VanDerWaalsContact O-N 3.08Å
360	V	92.4	Very high	88.1	Confident	0 Å²	0	39.3 Å²	39.3	0%	0	21%	0.205	C	C	.	.	H	α-helix	trans	-71.5	-37.6	175	168.5	0	0	0	0	112.4	F227 F228 M231 L344 L356 L357 L358 L362 A363 V364	F227-V360 HydrophobicContact CD1-CG2 3.76Å; F227-V360 HydrophobicContact CE1-CB 4.37Å; F227-V360 HydrophobicContact CE1-CG2 3.42Å; F227-V360 VanDerWaalsContact CE1-CG2 3.42Å; F227-V360 HydrophobicContact CE2-CG2 4.31Å; F227-V360 HydrophobicContact CG-CG2 4.35Å; F227-V360 HydrophobicContact CZ-CG2 3.72Å; F228-V360 HydrophobicContact CB-CG1 3.97Å; F228-V360 HydrophobicContact CD2-CG1 3.73Å; F228-V360 HydrophobicContact CG-CG1 4.35Å; M231-V360 HydrophobicContact CB-CG2 3.62Å; M231-V360 HydrophobicContact CG-CB 4.48Å; M231-V360 HydrophobicContact CG-CG2 3.78Å; L344-V360 HydrophobicContact CD1-CG1 4.11Å; L356-V360 WeakPolarHBondContact O-CG2 3.43Å; L356-V360 PolarHBondContact O-N 2.92Å; L356-V360 VanDerWaalsContact O-N 3.13Å; L357-V360 CarbonylContact O-C 3.53Å; L357-V360 PolarHBondContact O-N 3.44Å; L357-V360 VanDerWaalsContact O-N 3.08Å; L358-V360 VanDerWaalsContact C-N 3.28Å; L358-V360 PolarHBondContact O-N 3.08Å; V360-L362 VanDerWaalsContact C-N 3.35Å; V360-L362 PolarHBondContact O-N 2.66Å; V360-A363 PolarHBondContact O-N 3.06Å; V360-V364 HydrophobicContact CG1-CG2 4.2Å; V360-V364 WeakPolarHBondContact O-CG2 3.31Å; V360-V364 PolarHBondContact O-N 3.1Å
361	R	92.4	Very high	88.5	Confident	1 Å²	1	37.5 Å²	37.5	0%	0.004	20%	0.198	C	C	.	.	H	α-helix	trans	-57.6	-47.9	172	-62.9	-179.6	-157.1	-116.7	15.9	111.3	E170 V174 L344 S348 L357 L358 A363 V364 L365	E170-R361 IonicContact OE1-NH1 2.7Å; E170-R361 PolarHBondContact OE1-NH1 3.39Å; E170-R361 WeakPolarHBondContact OE2-CD 3.47Å; E170-R361 WeakPolarHBondContact OE2-CG 3.35Å; E170-R361 IonicContact OE2-CZ 3.7Å; E170-R361 IonicContact OE2-NE 3.76Å; E170-R361 IonicContact OE2-NH1 2.66Å; E170-R361 PolarHBondContact OE2-NH1 3.04Å; V174-R361 HydrophobicContact CG2-CB 3.8Å; L344-R361 HydrophobicContact CD1-CG 4.5Å; L344-R361 HydrophobicContact CD2-CB 4.47Å; L344-R361 HydrophobicContact CD2-CG 4.03Å; L344-R361 HydrophobicContact CG-CG 4.19Å; S348-R361 VanDerWaalsContact CB-NH1 3.28Å; S348-R361 VanDerWaalsContact CB-NH2 3.27Å; S348-R361 PolarHBondContact OG-NH1 2.9Å; S348-R361 PolarHBondContact OG-NH2 3.16Å; L357-R361 HydrophobicContact CD1-CG 4.46Å; L357-R361 HydrophobicContact CG-CG 4.48Å; L357-R361 WeakPolarHBondContact O-CG 3.38Å; L357-R361 PolarHBondContact O-N 3.44Å; L358-R361 PolarHBondContact O-N 2.89Å; R361-A363 VanDerWaalsContact C-N 3.32Å; R361-A363 PolarHBondContact O-N 2.7Å; R361-V364 PolarHBondContact O-N 2.97Å; R361-L365 VanDerWaalsContact O-CB 3.27Å; R361-L365 WeakPolarHBondContact O-CB 3.5Å; R361-L365 VanDerWaalsContact O-CG 3.23Å; R361-L365 WeakPolarHBondContact O-CG 3.28Å; R361-L365 PolarHBondContact O-N 2.99Å
362	L	93.7	Very high	89	Confident	77 Å²	77	34.5 Å²	34.5	40%	0.403	19%	0.187	S	C	.	.	H	α-helix	trans	-58.5	-42.9	175.7	-73.5	168	0	0	0	111.9	V174 F178 L358 V360 A366	V174-L362 HydrophobicContact CG1-CD2 3.66Å; V174-L362 HydrophobicContact CG1-CG 4.27Å; F178-L362 HydrophobicContact CE2-CD1 4.16Å; F178-L362 HydrophobicContact CZ-CD1 4.27Å; L358-L362 PolarHBondContact O-N 2.89Å; V360-L362 VanDerWaalsContact C-N 3.35Å; V360-L362 PolarHBondContact O-N 2.66Å; L362-A366 WeakPolarHBondContact O-CB 3.25Å; L362-A366 PolarHBondContact O-N 3.42Å
363	A	93.6	Very high	89.5	Confident	12 Å²	12	29.5 Å²	29.5	10%	0.099	17%	0.17	C	C	.	.	H	α-helix	trans	-65	-44.4	176.9	0	0	0	0	0	112.8	C224 F227 A359 V360 R361 A366 A367	C224-A363 HydrophobicContact CB-CB 3.92Å; C224-A363 WeakPolarHBondContact CB-O 3.34Å; F227-A363 HydrophobicContact CD1-CB 3.91Å; F227-A363 HydrophobicContact CE1-CB 4.4Å; A359-A363 PolarHBondContact O-N 2.9Å; A359-A363 VanDerWaalsContact O-N 3.08Å; V360-A363 PolarHBondContact O-N 3.06Å; R361-A363 VanDerWaalsContact C-N 3.32Å; R361-A363 PolarHBondContact O-N 2.7Å; A363-A366 PolarHBondContact O-N 3.21Å; A363-A367 WeakPolarHBondContact O-CB 3.5Å; A363-A367 PolarHBondContact O-N 3.34Å
364	V	93.1	Very high	89.9	Confident	0 Å²	0	25.2 Å²	25.2	0%	0	15%	0.148	C	C	.	.	H	α-helix	trans	-67.1	-44.1	177.6	172.8	0	0	0	0	110.9	L88 I166 M225 F228 L344 V360 R361 A366 A367 V368	L88-V364 HydrophobicContact CD1-CG1 4.49Å; I166-V364 HydrophobicContact CG2-CG1 4.24Å; M225-V364 HydrophobicContact CE-CG1 4.4Å; M225-V364 HydrophobicContact SD-CG2 4.29Å; F228-V364 HydrophobicContact CB-CG2 4.08Å; F228-V364 HydrophobicContact CD2-CG2 4.04Å; F228-V364 HydrophobicContact CG-CG2 4.26Å; L344-V364 HydrophobicContact CD2-CB 4.21Å; L344-V364 HydrophobicContact CD2-CG1 4.28Å; L344-V364 HydrophobicContact CD2-CG2 4.33Å; V360-V364 HydrophobicContact CG1-CG2 4.2Å; V360-V364 WeakPolarHBondContact O-CG2 3.31Å; V360-V364 PolarHBondContact O-N 3.1Å; R361-V364 PolarHBondContact O-N 2.97Å; V364-A366 VanDerWaalsContact C-N 3.34Å; V364-A366 PolarHBondContact O-N 3.37Å; V364-A367 PolarHBondContact O-N 3.17Å; V364-V368 HydrophobicContact CG1-CG1 4.46Å; V364-V368 WeakPolarHBondContact O-CG2 3.35Å; V364-V368 PolarHBondContact O-N 3.35Å
365	L	93.9	Very high	89.8	Confident	13 Å²	13	23.9 Å²	23.9	7%	0.068	14%	0.141	C	C	.	.	H	α-helix	trans	-59.5	-43	175.3	-74.7	168.1	0	0	0	111.8	I166 I167 E170 L171 V174 R361 V368 T369	I166-L365 HydrophobicContact CG2-CD2 4.43Å; I167-L365 HydrophobicContact CB-CD2 4.37Å; I167-L365 HydrophobicContact CG1-CD2 3.87Å; E170-L365 HydrophobicContact CB-CD1 4.39Å; E170-L365 HydrophobicContact CB-CD2 4.21Å; E170-L365 HydrophobicContact CB-CG 4.44Å; L171-L365 HydrophobicContact CB-CD1 4.49Å; L171-L365 HydrophobicContact CD1-CD1 4.43Å; V174-L365 HydrophobicContact CG2-CD1 3.88Å; R361-L365 VanDerWaalsContact O-CB 3.27Å; R361-L365 WeakPolarHBondContact O-CB 3.5Å; R361-L365 VanDerWaalsContact O-CG 3.23Å; R361-L365 WeakPolarHBondContact O-CG 3.28Å; R361-L365 PolarHBondContact O-N 2.99Å; L365-V368 WeakPolarHBondContact O-CG2 3.43Å; L365-T369 VanDerWaalsContact O-CB 3.28Å; L365-T369 WeakPolarHBondContact O-CB 3.4Å; L365-T369 PolarHBondContact O-N 3.02Å; L365-T369 PolarHBondContact O-OG1 3.21Å
366	A	92.3	Very high	89.5	Confident	42 Å²	42	18 Å²	18	35%	0.347	11%	0.111	S	C	.	.	H	α-helix	trans	-63	-46.6	173.7	0	0	0	0	0	111.9	L362 A363 V364 T369 L370	L362-A366 WeakPolarHBondContact O-CB 3.25Å; L362-A366 PolarHBondContact O-N 3.42Å; A363-A366 PolarHBondContact O-N 3.21Å; V364-A366 VanDerWaalsContact C-N 3.34Å; V364-A366 PolarHBondContact O-N 3.37Å; A366-T369 PolarHBondContact O-N 3.39Å; A366-L370 WeakPolarHBondContact O-CB 3.5Å; A366-L370 VanDerWaalsContact O-CG 3.3Å; A366-L370 WeakPolarHBondContact O-CG 3.32Å; A366-L370 PolarHBondContact O-N 2.96Å
367	A	91.8	Very high	89.1	Confident	0 Å²	0	19.8 Å²	19.8	0%	0	12%	0.116	C	C	.	.	H	α-helix	trans	-59.7	-48.3	179.1	0	0	0	0	0	112.8	S221 C224 M225 A363 V364 L370 T371	S221-A367 WeakPolarHBondContact OG-CB 3.36Å; S221-A367 PolarHBondContact OG-O 3.32Å; C224-A367 HydrophobicContact CB-CB 3.93Å; M225-A367 HydrophobicContact CE-CB 4.09Å; M225-A367 HydrophobicContact CG-CB 4.43Å; A363-A367 WeakPolarHBondContact O-CB 3.5Å; A363-A367 PolarHBondContact O-N 3.34Å; V364-A367 PolarHBondContact O-N 3.17Å; A367-L370 PolarHBondContact O-N 3.45Å; A367-T371 WeakPolarHBondContact O-CB 3.22Å; A367-T371 PolarHBondContact O-N 2.83Å; A367-T371 VanDerWaalsContact O-N 3.1Å; A367-T371 PolarHBondContact O-OG1 2.85Å
368	V	91.9	Very high	88.6	Confident	1 Å²	1	20.1 Å²	20.1	1%	0.006	12%	0.119	C	C	.	.	H	α-helix	trans	-66.3	-39.5	178.1	-58.7	0	0	0	0	111.6	Y163 I166 I167 M225 V364 L365 L370 T371 V372	Y163-V368 HydrophobicContact CD1-CB 3.56Å; Y163-V368 HydrophobicContact CD1-CG1 3.44Å; Y163-V368 VanDerWaalsContact CD1-CG1 3.44Å; Y163-V368 HydrophobicContact CE1-CB 4.15Å; Y163-V368 HydrophobicContact CE1-CG1 3.8Å; Y163-V368 HydrophobicContact CG-CB 3.81Å; Y163-V368 HydrophobicContact CG-CG1 4.22Å; I166-V368 HydrophobicContact CD1-CG1 4.06Å; I167-V368 HydrophobicContact CD1-CG2 4.27Å; I167-V368 HydrophobicContact CG1-CG2 4.14Å; M225-V368 HydrophobicContact CE-CG1 4.36Å; V364-V368 HydrophobicContact CG1-CG1 4.46Å; V364-V368 WeakPolarHBondContact O-CG2 3.35Å; V364-V368 PolarHBondContact O-N 3.35Å; L365-V368 WeakPolarHBondContact O-CG2 3.43Å; V368-L370 PolarHBondContact O-N 3.47Å; V368-T371 PolarHBondContact O-N 3.39Å; V368-V372 PolarHBondContact O-N 3.21Å
369	T	90.8	Very high	88.2	Confident	11 Å²	11	19.6 Å²	19.6	7%	0.067	12%	0.116	C	C	.	.	H	α-helix	trans	-61.1	-44.2	177.1	-58.6	0	0	0	0	111.8	F197 V201 L205 L365 A366 T371 P373	F197-T369 HydrophobicContact CE1-CG2 3.83Å; F197-T369 WeakPolarHBondContact CE1-OG1 3.27Å; F197-T369 HydrophobicContact CZ-CG2 3.9Å; F197-T369 WeakPolarHBondContact CZ-OG1 3.18Å; V201-T369 HydrophobicContact CG1-CG2 3.78Å; L205-T369 HydrophobicContact CD2-CG2 4.4Å; L365-T369 VanDerWaalsContact O-CB 3.28Å; L365-T369 WeakPolarHBondContact O-CB 3.4Å; L365-T369 PolarHBondContact O-N 3.02Å; L365-T369 PolarHBondContact O-OG1 3.21Å; A366-T369 PolarHBondContact O-N 3.39Å; T369-T371 PolarHBondContact O-N 2.73Å; T369-P373 VanDerWaalsContact O-CD 3.31Å; T369-P373 WeakPolarHBondContact O-CD 3.34Å
370	L	87.4	Confident	87.7	Confident	37 Å²	37	19.4 Å²	19.4	19%	0.194	11%	0.108	C	C	.	.	H	α-helix	trans	-67.9	-21.8	175.3	-68.9	173.1	0	0	0	113.1	T217 L220 A366 A367 V368	T217-L370 HydrophobicContact CG2-CD2 4.01Å; L220-L370 HydrophobicContact CD2-CD1 3.9Å; L220-L370 HydrophobicContact CG-CD1 4.31Å; A366-L370 WeakPolarHBondContact O-CB 3.5Å; A366-L370 VanDerWaalsContact O-CG 3.3Å; A366-L370 WeakPolarHBondContact O-CG 3.32Å; A366-L370 PolarHBondContact O-N 2.96Å; A367-L370 PolarHBondContact O-N 3.45Å; V368-L370 PolarHBondContact O-N 3.47Å
371	T	87.5	Confident	87	Confident	9 Å²	9	21.6 Å²	21.6	6%	0.055	12%	0.122	C	C	.	.	H	α-helix	trans	-89.8	-22	-178.8	-50.8	0	0	0	0	113.3	I80 Y163 S221 A367 V368 T369 V374 L375	I80-T371 HydrophobicContact CG2-CG2 3.87Å; Y163-T371 HydrophobicContact CE2-CG2 3.7Å; Y163-T371 VanDerWaalsContact OH-CG2 3.26Å; Y163-T371 WeakPolarHBondContact OH-CG2 3.46Å; S221-T371 PolarHBondContact OG-OG1 2.95Å; A367-T371 WeakPolarHBondContact O-CB 3.22Å; A367-T371 PolarHBondContact O-N 2.83Å; A367-T371 VanDerWaalsContact O-N 3.1Å; A367-T371 PolarHBondContact O-OG1 2.85Å; V368-T371 PolarHBondContact O-N 3.39Å; T369-T371 PolarHBondContact O-N 2.73Å; T371-V374 HydrophobicContact CG2-CB 4.47Å; T371-V374 HydrophobicContact CG2-CG2 4.36Å; T371-V374 VanDerWaalsContact O-CB 3.25Å; T371-V374 WeakPolarHBondContact O-CB 3.38Å; T371-V374 WeakPolarHBondContact O-CG2 3.37Å; T371-V374 PolarHBondContact O-N 3.42Å; T371-V374 VanDerWaalsContact O-N 3.1Å; T371-L375 PolarHBondContact O-N 3.2Å
372	V	87.6	Confident	86.4	Confident	0 Å²	0	21.5 Å²	21.5	0%	0	12%	0.122	C	C	.	.	H	α-helix	trans	-57.9	-46.2	177.8	173.1	0	0	0	0	113.4	M160 Y163 I202 V368 V374 L375 L376	M160-V372 HydrophobicContact CE-CG1 3.92Å; M160-V372 HydrophobicContact CG-CG1 4.49Å; Y163-V372 HydrophobicContact CD2-CG2 3.66Å; Y163-V372 HydrophobicContact CG-CG2 4.27Å; I202-V372 HydrophobicContact CG2-CB 4.12Å; I202-V372 HydrophobicContact CG2-CG1 3.47Å; I202-V372 VanDerWaalsContact CG2-CG1 3.47Å; V368-V372 PolarHBondContact O-N 3.21Å; V372-V374 PolarHBondContact O-N 2.91Å; V372-L375 PolarHBondContact O-N 3.43Å; V372-L375 VanDerWaalsContact O-N 3.12Å; V372-L376 HydrophobicContact CG1-CD1 4.44Å; V372-L376 PolarHBondContact O-N 2.72Å
373	P	81.6	Confident	85.7	Confident	16 Å²	16	19.1 Å²	19.1	10%	0.104	11%	0.11	C	C	.	.	H	α-helix	trans	-59	-30.4	175.5	-26	35.8	0	0	0	113.6	L205 T369 L376	L205-P373 HydrophobicContact CB-CG 4.06Å; T369-P373 VanDerWaalsContact O-CD 3.31Å; T369-P373 WeakPolarHBondContact O-CD 3.34Å; P373-L376 PolarHBondContact O-N 3.12Å
374	V	81.4	Confident	85	Confident	34 Å²	34	19.4 Å²	19.4	21%	0.206	11%	0.114	C	C	.	.	H	α-helix	trans	-65.2	-41.8	176.9	-164.2	0	0	0	0	110.9	L214 T371 V372 L376 F377 P378	L214-V374 HydrophobicContact CD1-CG2 4.04Å; L214-V374 HydrophobicContact CD2-CG1 4.3Å; L214-V374 HydrophobicContact CD2-CG2 4.09Å; L214-V374 HydrophobicContact CG-CG2 4.28Å; T371-V374 HydrophobicContact CG2-CB 4.47Å; T371-V374 HydrophobicContact CG2-CG2 4.36Å; T371-V374 VanDerWaalsContact O-CB 3.25Å; T371-V374 WeakPolarHBondContact O-CB 3.38Å; T371-V374 WeakPolarHBondContact O-CG2 3.37Å; T371-V374 PolarHBondContact O-N 3.42Å; T371-V374 VanDerWaalsContact O-N 3.1Å; V372-V374 PolarHBondContact O-N 2.91Å; V374-L376 VanDerWaalsContact C-N 3.34Å; V374-F377 PolarHBondContact O-N 3.23Å; V374-P378 WeakPolarHBondContact O-CD 3.3Å
375	L	83.4	Confident	84.1	Confident	17 Å²	17	22.5 Å²	22.5	9%	0.089	13%	0.128	C	C	.	.	H	α-helix	trans	-70.8	-27.8	179.6	-63.5	-175.1	0	0	0	113.2	A159 M160 Y163 T371 V372 P378 I379	A159-L375 VanDerWaalsContact C-CD1 3.46Å; A159-L375 HydrophobicContact CB-CD1 3.48Å; A159-L375 VanDerWaalsContact CB-CD1 3.48Å; A159-L375 HydrophobicContact CB-CD2 4.25Å; M160-L375 HydrophobicContact CG-CB 3.92Å; M160-L375 HydrophobicContact CG-CD1 3.72Å; M160-L375 HydrophobicContact SD-CB 4.4Å; Y163-L375 HydrophobicContact CD2-CD1 3.73Å; Y163-L375 HydrophobicContact CE2-CD1 3.32Å; Y163-L375 HydrophobicContact CE2-CG 4.02Å; T371-L375 PolarHBondContact O-N 3.2Å; V372-L375 PolarHBondContact O-N 3.43Å; V372-L375 VanDerWaalsContact O-N 3.12Å; L375-P378 WeakPolarHBondContact O-CD 3.31Å; L375-I379 WeakPolarHBondContact O-CG1 3.26Å
376	L	82.7	Confident	83.4	Confident	4 Å²	4	25.3 Å²	25.3	2%	0.021	14%	0.143	C	C	.	.	H	α-helix	trans	-68.6	-32.6	177.5	-80.7	167	0	0	0	112.7	M160 S206 V372 P373 V374 I379 H380 T402 L405	M160-L376 HydrophobicContact CE-CD1 4.44Å; M160-L376 HydrophobicContact CE-CD2 3.93Å; M160-L376 HydrophobicContact CE-CG 4.06Å; M160-L376 HydrophobicContact SD-CD2 3.86Å; M160-L376 HydrophobicContact SD-CG 3.93Å; S206-L376 VanDerWaalsContact CB-CD1 3.47Å; S206-L376 VanDerWaalsContact OG-CD1 3.28Å; S206-L376 WeakPolarHBondContact OG-CD1 3.33Å; V372-L376 HydrophobicContact CG1-CD1 4.44Å; V372-L376 PolarHBondContact O-N 2.72Å; P373-L376 PolarHBondContact O-N 3.12Å; V374-L376 VanDerWaalsContact C-N 3.34Å; L376-I379 PolarHBondContact O-N 3.1Å; L376-I379 VanDerWaalsContact O-N 3.11Å; L376-H380 PolarHBondContact O-CD2 3.31Å; L376-H380 PolarHBondContact O-N 3.08Å; L376-T402 HydrophobicContact CD1-CG2 4.16Å; L376-L405 HydrophobicContact CD2-CD2 4Å
377	F	79.9	Confident	82.7	Confident	88 Å²	88	28.6 Å²	28.6	39%	0.386	15%	0.154	S	C	.	.	H	α-helix	trans	-60.6	-48.3	-177.1	175	-91.7	0	0	0	113.7	L211 P296 V374 I379 H380 T381	L211-F377 HydrophobicContact CD1-CB 4.31Å; L211-F377 HydrophobicContact CD1-CD2 3.87Å; L211-F377 HydrophobicContact CD1-CG 4.2Å; P296-F377 HydrophobicContact CB-CE1 4.28Å; V374-F377 PolarHBondContact O-N 3.23Å; F377-I379 VanDerWaalsContact C-N 3.34Å; F377-I379 PolarHBondContact O-N 2.98Å; F377-H380 PolarHBondContact O-N 2.92Å; F377-T381 PolarHBondContact O-N 3.28Å; F377-T381 PolarHBondContact O-OG1 3.2Å
378	P	80	Confident	82.1	Confident	9 Å²	9	32.2 Å²	32.2	6%	0.058	17%	0.17	C	C	.	.	H	α-helix	trans	-56.3	-43.7	168.8	-27.3	35.1	0	0	0	113.1	I152 P292 T293 V374 L375 H380 T381 S382	I152-P378 HydrophobicContact CG2-CB 4.17Å; P292-P378 HydrophobicContact CB-CB 4.45Å; T293-P378 HydrophobicContact CG2-CG 4.02Å; V374-P378 WeakPolarHBondContact O-CD 3.3Å; L375-P378 WeakPolarHBondContact O-CD 3.31Å; P378-H380 PolarHBondContact O-N 3.14Å; P378-T381 WeakPolarHBondContact O-CB 3.23Å; P378-T381 PolarHBondContact O-N 3.04Å; P378-T381 VanDerWaalsContact O-N 3.14Å; P378-S382 PolarHBondContact O-N 2.96Å; P378-S382 PolarHBondContact O-OG 3.43Å
379	I	82.3	Confident	81.2	Confident	1 Å²	1	36.2 Å²	36.2	1%	0.005	20%	0.196	C	C	.	.	H	α-helix	trans	-67	-40.9	-176.9	-52	164.5	0	0	0	111.5	T153 N156 I157 M160 L375 L376 F377 T381 S382 V383 L405	T153-I379 HydrophobicContact CG2-CG2 4.1Å; N156-I379 HydrophobicContact CB-CD1 3.59Å; N156-I379 HydrophobicContact CB-CG1 3.45Å; N156-I379 VanDerWaalsContact CB-CG1 3.45Å; I157-I379 HydrophobicContact CG1-CD1 4.32Å; M160-I379 HydrophobicContact SD-CD1 3.79Å; L375-I379 WeakPolarHBondContact O-CG1 3.26Å; L376-I379 PolarHBondContact O-N 3.1Å; L376-I379 VanDerWaalsContact O-N 3.11Å; F377-I379 VanDerWaalsContact C-N 3.34Å; F377-I379 PolarHBondContact O-N 2.98Å; I379-T381 PolarHBondContact O-N 2.89Å; I379-S382 PolarHBondContact O-N 3.32Å; I379-V383 HydrophobicContact CG2-CG2 3.73Å; I379-V383 VanDerWaalsContact O-CB 3.31Å; I379-V383 WeakPolarHBondContact O-CB 3.46Å; I379-V383 VanDerWaalsContact O-CG2 3.3Å; I379-V383 WeakPolarHBondContact O-CG2 3.18Å; I379-V383 PolarHBondContact O-N 3.26Å; I379-L405 HydrophobicContact CB-CD1 4.26Å; I379-L405 HydrophobicContact CD1-CD1 3.81Å; I379-L405 HydrophobicContact CD1-CD2 4.31Å; I379-L405 HydrophobicContact CG2-CD1 3.45Å; I379-L405 VanDerWaalsContact CG2-CD1 3.45Å
380	H	82.2	Confident	80.1	Confident	35 Å²	35	39.7 Å²	39.7	16%	0.162	23%	0.234	C	C	.	.	H	α-helix	trans	-58.9	-36.4	173.6	-77.7	-63.1	0	0	0	112.1	L376 F377 P378 G384 H398 T401 T402	L376-H380 PolarHBondContact O-CD2 3.31Å; L376-H380 PolarHBondContact O-N 3.08Å; F377-H380 PolarHBondContact O-N 2.92Å; P378-H380 PolarHBondContact O-N 3.14Å; H380-G384 WeakPolarHBondContact O-CA 3.11Å; H380-G384 PolarHBondContact O-N 3.28Å; H380-H398 AromaticContact CD2-CE1 3.57Å; H380-H398 AromaticContact CD2-ND1 3.7Å; H380-H398 AromaticContact CE1-CE1 3.67Å; H380-H398 AromaticContact CE1-ND1 3.28Å; H380-H398 PolarHBondContact CE1-ND1 2.85Å; H380-H398 VanDerWaalsContact CE1-ND1 3.28Å; H380-H398 PolarHBondContact CE1-O 3.44Å; H380-H398 AromaticContact CG-ND1 3.69Å; H380-H398 AromaticContact ND1-ND1 3.43Å; H380-H398 PolarHBondContact ND1-ND1 3.38Å; H380-H398 AromaticContact NE2-CE1 3.34Å; H380-H398 PolarHBondContact NE2-CE1 3.29Å; H380-H398 VanDerWaalsContact NE2-CE1 3.34Å; H380-H398 AromaticContact NE2-ND1 3.44Å; H380-H398 PolarHBondContact NE2-ND1 3.15Å; H380-T401 WeakPolarHBondContact ND1-CG2 3.48Å; H380-T402 PolarHBondContact CE1-OG1 2.91Å; H380-T402 PolarHBondContact NE2-OG1 3.22Å
381	T	76.9	Confident	79.4	Confident	46 Å²	46	44.6 Å²	44.6	28%	0.282	25%	0.254	S	S	.	.	H	α-helix	trans	-67.9	-50.1	175.8	-55.7	0	0	0	0	111	F377 P378 I379 G384 H385	F377-T381 PolarHBondContact O-N 3.28Å; F377-T381 PolarHBondContact O-OG1 3.2Å; P378-T381 WeakPolarHBondContact O-CB 3.23Å; P378-T381 PolarHBondContact O-N 3.04Å; P378-T381 VanDerWaalsContact O-N 3.14Å; I379-T381 PolarHBondContact O-N 2.89Å; T381-G384 PolarHBondContact O-N 3.33Å; T381-H385 WeakPolarHBondContact O-CB 3.41Å; T381-H385 PolarHBondContact O-CD2 3.49Å; T381-H385 VanDerWaalsContact O-CD2 3.29Å; T381-H385 PolarHBondContact O-N 3.46Å
382	S	79.8	Confident	78.7	Confident	0 Å²	0	51.2 Å²	51.2	0%	0	29%	0.289	C	S	.	.	H	α-helix	trans	-60.6	-51.2	177.5	-58.5	0	0	0	0	112.8	E133 S149 I152 P378 I379 G384 H385 L386	E133-S382 VanDerWaalsContact OE1-CA 3.26Å; E133-S382 WeakPolarHBondContact OE1-CA 3.27Å; E133-S382 VanDerWaalsContact OE1-CB 3.23Å; E133-S382 WeakPolarHBondContact OE1-CB 3.45Å; E133-S382 PolarHBondContact OE1-OG 3.47Å; S149-S382 PolarHBondContact OG-O 2.93Å; I152-S382 WeakPolarHBondContact CG2-OG 3.48Å; P378-S382 PolarHBondContact O-N 2.96Å; P378-S382 PolarHBondContact O-OG 3.43Å; I379-S382 PolarHBondContact O-N 3.32Å; S382-G384 PolarHBondContact O-N 2.79Å; S382-H385 PolarHBondContact O-N 2.83Å; S382-L386 WeakPolarHBondContact O-CB 3.41Å; S382-L386 PolarHBondContact O-N 3.15Å
383	V	80.6	Confident	78.2	Confident	26 Å²	26	56.9 Å²	56.9	16%	0.158	31%	0.314	C	S	.	.	H	α-helix	trans	-65.7	-38.8	-179.6	173.8	0	0	0	0	111	I379 L386 L387 T401	I379-V383 HydrophobicContact CG2-CG2 3.73Å; I379-V383 VanDerWaalsContact O-CB 3.31Å; I379-V383 WeakPolarHBondContact O-CB 3.46Å; I379-V383 VanDerWaalsContact O-CG2 3.3Å; I379-V383 WeakPolarHBondContact O-CG2 3.18Å; I379-V383 PolarHBondContact O-N 3.26Å; V383-L386 PolarHBondContact O-N 2.88Å; V383-L387 HydrophobicContact CG1-CD1 3.74Å; V383-L387 HydrophobicContact CG1-CG 4.25Å; V383-L387 WeakPolarHBondContact O-CB 3.36Å; V383-L387 PolarHBondContact O-N 2.7Å; V383-T401 HydrophobicContact CB-CG2 4.45Å; V383-T401 HydrophobicContact CG1-CG2 4.06Å
384	G	78.3	Confident	78.3	Confident	18 Å²	18	58.3 Å²	58.3	19%	0.186	32%	0.324	C	S	.	.	H	α-helix	trans	-59.6	-49.7	172.7	0	0	0	0	0	112.2	H380 T381 S382 L386 F388	H380-G384 WeakPolarHBondContact O-CA 3.11Å; H380-G384 PolarHBondContact O-N 3.28Å; T381-G384 PolarHBondContact O-N 3.33Å; S382-G384 PolarHBondContact O-N 2.79Å; G384-L386 VanDerWaalsContact C-N 3.31Å; G384-L386 PolarHBondContact O-N 3.39Å; G384-F388 CarbonylContact O-C 3.58Å; G384-F388 WeakPolarHBondContact O-CA 3.44Å; G384-F388 PolarHBondContact O-N 2.87Å
385	H	74.6	Confident	78.3	Confident	65 Å²	65	62.7 Å²	62.7	30%	0.301	34%	0.337	S	S	.	.	H	α-helix	trans	-65.5	-30.1	176.3	-82.6	-58.9	0	0	0	113.7	K145 T381 S382	K145-H385 VanDerWaalsContact CE-O 3.27Å; K145-H385 WeakPolarHBondContact CE-O 3.17Å; K145-H385 PolarHBondContact NZ-O 3.43Å; T381-H385 WeakPolarHBondContact O-CB 3.41Å; T381-H385 PolarHBondContact O-CD2 3.49Å; T381-H385 VanDerWaalsContact O-CD2 3.29Å; T381-H385 PolarHBondContact O-N 3.46Å; S382-H385 PolarHBondContact O-N 2.83Å
386	L	77.8	Confident	78.4	Confident	73 Å²	73	67.9 Å²	67.9	38%	0.382	36%	0.364	S	S	.	.	H	α-helix	trans	-78.4	-52.1	-179.4	-175.4	61.4	0	0	0	112.5	L146 S382 V383 G384	L146-L386 HydrophobicContact CD1-CD1 3.72Å; S382-L386 WeakPolarHBondContact O-CB 3.41Å; S382-L386 PolarHBondContact O-N 3.15Å; V383-L386 PolarHBondContact O-N 2.88Å; G384-L386 VanDerWaalsContact C-N 3.31Å; G384-L386 PolarHBondContact O-N 3.39Å
387	L	78.4	Confident	78.4	Confident	110 Å²	110	70.5 Å²	70.5	58%	0.576	37%	0.373	S	S	*	.	H	α-helix	trans	-91.8	-28.4	-172.3	-61.2	-178.1	0	0	0	114	V383 P389	V383-L387 HydrophobicContact CG1-CD1 3.74Å; V383-L387 HydrophobicContact CG1-CG 4.25Å; V383-L387 WeakPolarHBondContact O-CB 3.36Å; V383-L387 PolarHBondContact O-N 2.7Å; L387-P389 VanDerWaalsContact C-CD 3.5Å
388	F	79.1	Confident	78.6	Confident	77 Å²	77	67.8 Å²	67.8	34%	0.338	36%	0.362	S	S	.	.	S	Bend	trans	-134.2	55.5	-170.2	-55.2	-75.6	0	0	0	112.8	G384 G390 K391 R397	G384-F388 CarbonylContact O-C 3.58Å; G384-F388 WeakPolarHBondContact O-CA 3.44Å; G384-F388 PolarHBondContact O-N 2.87Å; F388-G390 PolarHBondContact O-N 2.67Å; F388-K391 HydrophobicContact CB-CB 4.41Å; F388-K391 PolarHBondContact O-N 3.37Å; F388-R397 HydrophobicContact CD2-CG 4.26Å; F388-R397 HydrophobicContact CE2-CG 4.12Å
389	P	72.4	Confident	78.9	Confident	84 Å²	84	69 Å²	69	55%	0.545	37%	0.373	S	S	.	.	T	Hydrogen-bonded Turn	trans	-57.4	126.2	-178.8	26	-35.2	0	0	0	111.4	L387 K391	L387-P389 VanDerWaalsContact C-CD 3.5Å; P389-K391 PolarHBondContact O-N 3.01Å
390	G	67.8	Low	79.2	Confident	84 Å²	84	73.7 Å²	73.7	87%	0.866	40%	0.396	S	S	*	.	T	Hydrogen-bonded Turn	trans	74.3	17.2	175.1	0	0	0	0	0	116	F388	F388-G390 PolarHBondContact O-N 2.67Å
391	K	73.6	Confident	79.4	Confident	140 Å²	140	73.2 Å²	73.2	61%	0.609	40%	0.396	S	S	*	.			trans	-104.7	127	174	-67	-168.9	175.7	-173.8	0	112.4	F388 P389 R397	F388-K391 HydrophobicContact CB-CB 4.41Å; F388-K391 PolarHBondContact O-N 3.37Å; P389-K391 PolarHBondContact O-N 3.01Å; K391-R397 PolarHBondContact O-NH1 3.37Å; K391-R397 PolarHBondContact O-NH2 2.92Å
392	D	73.4	Confident	80	Confident	148 Å²	148	71 Å²	71	79%	0.791	38%	0.383	S	S	*	.			trans	-53.8	163	179.4	-56.6	-62.5	0	0	0	114.1	S394 R397	D392-S394 PolarHBondContact O-N 3.05Å; D392-R397 VanDerWaalsContact O-CZ 3.25Å; D392-R397 PolarHBondContact O-NH1 3.32Å; D392-R397 PolarHBondContact O-NH2 2.74Å
393	F	76.8	Confident	80.6	Confident	120 Å²	120	75.8 Å²	75.8	53%	0.526	41%	0.408	S	S	.	.			trans	-58.6	131.6	179.2	179.1	-90.6	0	0	0	111.4	W395 H398	F393-W395 AromaticContact CE1-CD2 3.93Å; F393-W395 HydrophobicContact CE1-CD2 3.93Å; F393-W395 HydrophobicContact CE1-CE3 4.46Å; F393-W395 AromaticContact CE1-CG 3.93Å; F393-W395 HydrophobicContact CE1-CG 3.93Å; F393-W395 HydrophobicContact CZ-CD2 4.18Å; F393-W395 HydrophobicContact CZ-CE3 4.25Å; F393-H398 HydrophobicContact CE2-CB 3.91Å; F393-H398 AromaticContact CE2-CG 4Å; F393-H398 HydrophobicContact CZ-CB 3.96Å
394	S	82.9	Confident	81.1	Confident	46 Å²	46	79 Å²	79	32%	0.322	43%	0.428	S	S	.	.			trans	-132	124.7	174.5	171.9	0	0	0	0	109.2	D392 I396 R397 H398	D392-S394 PolarHBondContact O-N 3.05Å; S394-I396 VanDerWaalsContact C-N 3.3Å; S394-I396 PolarHBondContact O-N 3.2Å; S394-R397 WeakPolarHBondContact O-CB 3.32Å; S394-R397 PolarHBondContact O-N 3.37Å; S394-R397 VanDerWaalsContact O-N 3.15Å; S394-H398 PolarHBondContact O-N 3.16Å
395	W	80.7	Confident	81.7	Confident	126 Å²	126	79.4 Å²	79.4	48%	0.477	43%	0.425	S	S	.	.	H	α-helix	trans	-55.1	-43.4	178.1	-90.2	119.8	0	0	0	113	K209 F393 R397 H398 A399	K209-W395 HydrophobicContact CB-CH2 3.66Å; K209-W395 HydrophobicContact CB-CZ2 3.82Å; K209-W395 HydrophobicContact CD-CZ2 3.84Å; K209-W395 HydrophobicContact CG-CH2 3.95Å; K209-W395 HydrophobicContact CG-CZ2 3.75Å; F393-W395 AromaticContact CE1-CD2 3.93Å; F393-W395 HydrophobicContact CE1-CD2 3.93Å; F393-W395 HydrophobicContact CE1-CE3 4.46Å; F393-W395 AromaticContact CE1-CG 3.93Å; F393-W395 HydrophobicContact CE1-CG 3.93Å; F393-W395 HydrophobicContact CZ-CD2 4.18Å; F393-W395 HydrophobicContact CZ-CE3 4.25Å; W395-R397 PolarHBondContact O-N 2.79Å; W395-H398 PolarHBondContact O-N 3.35Å; W395-A399 WeakPolarHBondContact O-CB 3.17Å; W395-A399 PolarHBondContact O-N 3.01Å
396	I	85.4	Confident	82.5	Confident	126 Å²	126	76.6 Å²	76.6	65%	0.646	41%	0.413	S	S	*	.	H	α-helix	trans	-62.4	-45.1	178.5	-61	171.3	0	0	0	110.1	S394 H398 I400	S394-I396 VanDerWaalsContact C-N 3.3Å; S394-I396 PolarHBondContact O-N 3.2Å; I396-H398 PolarHBondContact O-N 2.99Å; I396-I400 HydrophobicContact CG2-CD1 3.68Å; I396-I400 HydrophobicContact CG2-CG1 4.42Å; I396-I400 WeakPolarHBondContact O-CB 3.22Å; I396-I400 VanDerWaalsContact O-CG1 3.25Å; I396-I400 WeakPolarHBondContact O-CG1 3.47Å; I396-I400 PolarHBondContact O-N 3.4Å
397	R	83.6	Confident	83.2	Confident	58 Å²	58	75.3 Å²	75.3	22%	0.219	41%	0.412	C	S	.	.	H	α-helix	trans	-63.3	-42.2	177.4	-172.5	175.3	80.9	-139.7	11.2	111.9	F388 K391 D392 S394 W395 T401	F388-R397 HydrophobicContact CD2-CG 4.26Å; F388-R397 HydrophobicContact CE2-CG 4.12Å; K391-R397 PolarHBondContact O-NH1 3.37Å; K391-R397 PolarHBondContact O-NH2 2.92Å; D392-R397 VanDerWaalsContact O-CZ 3.25Å; D392-R397 PolarHBondContact O-NH1 3.32Å; D392-R397 PolarHBondContact O-NH2 2.74Å; S394-R397 WeakPolarHBondContact O-CB 3.32Å; S394-R397 PolarHBondContact O-N 3.37Å; S394-R397 VanDerWaalsContact O-N 3.15Å; W395-R397 PolarHBondContact O-N 2.79Å; R397-T401 WeakPolarHBondContact O-CB 3.38Å; R397-T401 PolarHBondContact O-N 3.28Å; R397-T401 PolarHBondContact O-OG1 3.3Å
398	H	83.2	Confident	83.9	Confident	32 Å²	32	71.8 Å²	71.8	15%	0.148	40%	0.403	C	S	.	.	H	α-helix	trans	-61.6	-57.1	177.3	178.6	55.4	0	0	0	110.2	H380 F393 S394 W395 I396 I400 T401 T402	H380-H398 AromaticContact CD2-CE1 3.57Å; H380-H398 AromaticContact CD2-ND1 3.7Å; H380-H398 AromaticContact CE1-CE1 3.67Å; H380-H398 AromaticContact CE1-ND1 3.28Å; H380-H398 PolarHBondContact CE1-ND1 2.85Å; H380-H398 VanDerWaalsContact CE1-ND1 3.28Å; H380-H398 PolarHBondContact CE1-O 3.44Å; H380-H398 AromaticContact CG-ND1 3.69Å; H380-H398 AromaticContact ND1-ND1 3.43Å; H380-H398 PolarHBondContact ND1-ND1 3.38Å; H380-H398 AromaticContact NE2-CE1 3.34Å; H380-H398 PolarHBondContact NE2-CE1 3.29Å; H380-H398 VanDerWaalsContact NE2-CE1 3.34Å; H380-H398 AromaticContact NE2-ND1 3.44Å; H380-H398 PolarHBondContact NE2-ND1 3.15Å; F393-H398 HydrophobicContact CE2-CB 3.91Å; F393-H398 AromaticContact CE2-CG 4Å; F393-H398 HydrophobicContact CZ-CB 3.96Å; S394-H398 PolarHBondContact O-N 3.16Å; W395-H398 PolarHBondContact O-N 3.35Å; I396-H398 PolarHBondContact O-N 2.99Å; H398-I400 PolarHBondContact O-N 3.04Å; H398-T401 WeakPolarHBondContact O-CA 3.38Å; H398-T401 WeakPolarHBondContact O-CB 3.29Å; H398-T401 PolarHBondContact O-N 3.37Å; H398-T402 PolarHBondContact O-N 2.91Å; H398-T402 PolarHBondContact O-OG1 3.11Å
399	A	86.9	Confident	84.6	Confident	35 Å²	35	68.3 Å²	68.3	29%	0.289	39%	0.388	S	S	.	.	H	α-helix	trans	-58.9	-42.3	-179.6	0	0	0	0	0	113.7	L207 W395 T401 T402 L403	L207-A399 HydrophobicContact CD2-CB 3.93Å; W395-A399 WeakPolarHBondContact O-CB 3.17Å; W395-A399 PolarHBondContact O-N 3.01Å; A399-T401 VanDerWaalsContact C-N 3.31Å; A399-T401 PolarHBondContact O-N 3.4Å; A399-T402 PolarHBondContact O-N 3.21Å; A399-L403 VanDerWaalsContact O-CB 3.3Å; A399-L403 WeakPolarHBondContact O-CB 3.33Å; A399-L403 PolarHBondContact O-N 3.31Å
400	I	89.2	Confident	85.7	Confident	98 Å²	98	64.8 Å²	64.8	50%	0.503	36%	0.364	S	S	.	.	H	α-helix	trans	-61.5	-41	174.1	-70.5	171.6	0	0	0	110.8	I396 H398 T404	I396-I400 HydrophobicContact CG2-CD1 3.68Å; I396-I400 HydrophobicContact CG2-CG1 4.42Å; I396-I400 WeakPolarHBondContact O-CB 3.22Å; I396-I400 VanDerWaalsContact O-CG1 3.25Å; I396-I400 WeakPolarHBondContact O-CG1 3.47Å; I396-I400 PolarHBondContact O-N 3.4Å; H398-I400 PolarHBondContact O-N 3.04Å; I400-T404 VanDerWaalsContact O-CB 3.25Å; I400-T404 WeakPolarHBondContact O-CB 3.26Å; I400-T404 PolarHBondContact O-N 3.45Å; I400-T404 PolarHBondContact O-OG1 2.82Å
401	T	87.1	Confident	86.9	Confident	26 Å²	26	65.7 Å²	65.7	16%	0.16	35%	0.348	C	S	.	.	H	α-helix	trans	-65.4	-44.2	177.3	-56.2	0	0	0	0	111.3	H380 V383 R397 H398 A399 L405	H380-T401 WeakPolarHBondContact ND1-CG2 3.48Å; V383-T401 HydrophobicContact CB-CG2 4.45Å; V383-T401 HydrophobicContact CG1-CG2 4.06Å; R397-T401 WeakPolarHBondContact O-CB 3.38Å; R397-T401 PolarHBondContact O-N 3.28Å; R397-T401 PolarHBondContact O-OG1 3.3Å; H398-T401 WeakPolarHBondContact O-CA 3.38Å; H398-T401 WeakPolarHBondContact O-CB 3.29Å; H398-T401 PolarHBondContact O-N 3.37Å; A399-T401 VanDerWaalsContact C-N 3.31Å; A399-T401 PolarHBondContact O-N 3.4Å; T401-L405 WeakPolarHBondContact O-CB 3.17Å; T401-L405 PolarHBondContact O-N 2.88Å
402	T	88.9	Confident	87.9	Confident	0 Å²	0	63 Å²	63	0%	0	34%	0.34	C	S	.	.	H	α-helix	trans	-60.4	-49.8	177.7	-47.6	0	0	0	0	110.7	L203 L207 L376 H380 H398 A399 L405 L406	L203-T402 HydrophobicContact CD1-CG2 4.19Å; L207-T402 HydrophobicContact CD2-CG2 4.22Å; L376-T402 HydrophobicContact CD1-CG2 4.16Å; H380-T402 PolarHBondContact CE1-OG1 2.91Å; H380-T402 PolarHBondContact NE2-OG1 3.22Å; H398-T402 PolarHBondContact O-N 2.91Å; H398-T402 PolarHBondContact O-OG1 3.11Å; A399-T402 PolarHBondContact O-N 3.21Å; T402-L405 PolarHBondContact O-N 2.83Å; T402-L406 VanDerWaalsContact O-CB 3.24Å; T402-L406 WeakPolarHBondContact O-CB 3.13Å; T402-L406 PolarHBondContact O-N 3.44Å
403	L	91.5	Very high	89	Confident	99 Å²	99	56 Å²	56	52%	0.518	30%	0.302	S	S	.	.	H	α-helix	trans	-64.6	-46.1	-178.9	-178.7	63.1	0	0	0	111.8	L203 A399 L405 A407	L203-L403 HydrophobicContact CD2-CD1 4.41Å; A399-L403 VanDerWaalsContact O-CB 3.3Å; A399-L403 WeakPolarHBondContact O-CB 3.33Å; A399-L403 PolarHBondContact O-N 3.31Å; L403-L405 VanDerWaalsContact C-N 3.34Å; L403-L405 PolarHBondContact O-N 3.27Å; L403-A407 WeakPolarHBondContact O-CB 3.34Å; L403-A407 PolarHBondContact O-N 3.29Å
404	T	91.3	Very high	89.8	Confident	95 Å²	95	52.4 Å²	52.4	58%	0.583	29%	0.289	S	S	*	.	H	α-helix	trans	-62.2	-43.1	179.4	-54.9	0	0	0	0	111.1	I400 G408	I400-T404 VanDerWaalsContact O-CB 3.25Å; I400-T404 WeakPolarHBondContact O-CB 3.26Å; I400-T404 PolarHBondContact O-N 3.45Å; I400-T404 PolarHBondContact O-OG1 2.82Å; T404-G408 PolarHBondContact O-N 2.81Å
405	L	90.6	Very high	90.2	Very high	25 Å²	25	57.9 Å²	57.9	13%	0.131	31%	0.307	C	S	.	.	H	α-helix	trans	-71.1	-46	-179.7	-165.6	147.9	0	0	0	111.8	I157 M160 L376 I379 T401 T402 L403 A407 G408 T409	I157-L405 HydrophobicContact CD1-CD1 4.3Å; I157-L405 HydrophobicContact CG1-CD1 4.17Å; M160-L405 HydrophobicContact CE-CD2 3.43Å; M160-L405 VanDerWaalsContact CE-CD2 3.43Å; M160-L405 HydrophobicContact SD-CD2 3.56Å; M160-L405 VanDerWaalsContact SD-CD2 3.56Å; L376-L405 HydrophobicContact CD2-CD2 4Å; I379-L405 HydrophobicContact CB-CD1 4.26Å; I379-L405 HydrophobicContact CD1-CD1 3.81Å; I379-L405 HydrophobicContact CD1-CD2 4.31Å; I379-L405 HydrophobicContact CG2-CD1 3.45Å; I379-L405 VanDerWaalsContact CG2-CD1 3.45Å; T401-L405 WeakPolarHBondContact O-CB 3.17Å; T401-L405 PolarHBondContact O-N 2.88Å; T402-L405 PolarHBondContact O-N 2.83Å; L403-L405 VanDerWaalsContact C-N 3.34Å; L403-L405 PolarHBondContact O-N 3.27Å; L405-A407 VanDerWaalsContact C-N 3.32Å; L405-A407 PolarHBondContact O-N 3.12Å; L405-G408 PolarHBondContact O-N 3.35Å; L405-G408 VanDerWaalsContact O-N 3.17Å; L405-T409 HydrophobicContact CD2-CG2 3.84Å; L405-T409 PolarHBondContact O-N 3.43Å; L405-T409 PolarHBondContact O-OG1 3.26Å
406	L	91.9	Very high	90.7	Very high	7 Å²	7	52.8 Å²	52.8	4%	0.037	29%	0.289	C	S	.	.	H	α-helix	trans	-64.2	-37	179.6	-174.1	62.8	0	0	0	112	I202 L203 T402 T409 N410	I202-L406 HydrophobicContact CG2-CD1 3.94Å; I202-L406 HydrophobicContact CG2-CD2 4.3Å; L203-L406 HydrophobicContact CB-CD2 3.78Å; L203-L406 HydrophobicContact CD1-CD2 4.14Å; T402-L406 VanDerWaalsContact O-CB 3.24Å; T402-L406 WeakPolarHBondContact O-CB 3.13Å; T402-L406 PolarHBondContact O-N 3.44Å; L406-T409 PolarHBondContact O-OG1 3.45Å; L406-N410 WeakPolarHBondContact O-CB 3.27Å; L406-N410 PolarHBondContact O-N 3.5Å; L406-N410 PolarHBondContact O-ND2 2.85Å
407	A	93.1	Very high	90.8	Very high	45 Å²	45	51.2 Å²	51.2	37%	0.372	29%	0.287	S	S	.	.	H	α-helix	trans	-64.5	-46.4	171.2	0	0	0	0	0	111.4	L403 L405 T409 N410 I411	L403-A407 WeakPolarHBondContact O-CB 3.34Å; L403-A407 PolarHBondContact O-N 3.29Å; L405-A407 VanDerWaalsContact C-N 3.32Å; L405-A407 PolarHBondContact O-N 3.12Å; A407-T409 PolarHBondContact O-N 3.1Å; A407-N410 PolarHBondContact O-N 3.23Å; A407-I411 VanDerWaalsContact O-CG1 3.31Å; A407-I411 WeakPolarHBondContact O-CG1 3.49Å; A407-I411 PolarHBondContact O-N 3.41Å
408	G	93.5	Very high	91.1	Very high	37 Å²	37	49 Å²	49	38%	0.381	28%	0.281	S	S	.	.	H	α-helix	trans	-60.5	-42.1	177.8	0	0	0	0	0	113.6	T404 L405 L412	T404-G408 PolarHBondContact O-N 2.81Å; L405-G408 PolarHBondContact O-N 3.35Å; L405-G408 VanDerWaalsContact O-N 3.17Å; G408-L412 VanDerWaalsContact O-CB 3.31Å; G408-L412 WeakPolarHBondContact O-CB 3.29Å; G408-L412 PolarHBondContact O-N 3Å
409	T	93.8	Very high	91.6	Very high	3 Å²	3	47.5 Å²	47.5	2%	0.018	27%	0.274	C	S	.	.	H	α-helix	trans	-73.3	-33.5	177.3	55.1	0	0	0	0	112.8	I157 M160 L161 L164 L405 L406 A407 L412 V413	I157-T409 HydrophobicContact CG2-CG2 4.21Å; M160-T409 HydrophobicContact CB-CG2 4.44Å; L161-T409 HydrophobicContact CD2-CG2 4.19Å; L161-T409 WeakPolarHBondContact CD2-O 3.29Å; L161-T409 HydrophobicContact CG-CG2 4.39Å; L164-T409 WeakPolarHBondContact CD1-OG1 3.15Å; L405-T409 HydrophobicContact CD2-CG2 3.84Å; L405-T409 PolarHBondContact O-N 3.43Å; L405-T409 PolarHBondContact O-OG1 3.26Å; L406-T409 PolarHBondContact O-OG1 3.45Å; A407-T409 PolarHBondContact O-N 3.1Å; T409-L412 PolarHBondContact O-N 3.34Å; T409-V413 WeakPolarHBondContact O-CB 3.43Å; T409-V413 PolarHBondContact O-N 3.4Å
410	N	94.1	Very high	91.8	Very high	10 Å²	10	47 Å²	47	5%	0.053	27%	0.265	C	S	.	.	H	α-helix	trans	-64.8	-45.7	171.7	-89.3	-94.2	0	0	0	111.9	V194 I195 S198 L406 A407 L412 V413 I414	V194-N410 PolarHBondContact O-OD1 3.42Å; I195-N410 WeakPolarHBondContact CA-OD1 3.44Å; S198-N410 VanDerWaalsContact CB-ND2 3.31Å; S198-N410 WeakPolarHBondContact CB-ND2 3.5Å; S198-N410 PolarHBondContact OG-ND2 3.4Å; S198-N410 PolarHBondContact OG-OD1 3.01Å; L406-N410 WeakPolarHBondContact O-CB 3.27Å; L406-N410 PolarHBondContact O-N 3.5Å; L406-N410 PolarHBondContact O-ND2 2.85Å; A407-N410 PolarHBondContact O-N 3.23Å; N410-L412 VanDerWaalsContact C-N 3.33Å; N410-L412 PolarHBondContact O-N 3.48Å; N410-V413 WeakPolarHBondContact O-CG1 3.46Å; N410-I414 WeakPolarHBondContact O-CD1 3.35Å; N410-I414 VanDerWaalsContact O-CG1 3.28Å; N410-I414 WeakPolarHBondContact O-CG1 3.47Å; N410-I414 PolarHBondContact O-N 3.02Å
411	I	94.4	Very high	92	Very high	104 Å²	104	44.5 Å²	44.5	53%	0.533	25%	0.249	S	C	.	.	H	α-helix	trans	-60.3	-46	175.6	-67.7	165.1	0	0	0	110.2	A407 I414 F415	A407-I411 VanDerWaalsContact O-CG1 3.31Å; A407-I411 WeakPolarHBondContact O-CG1 3.49Å; A407-I411 PolarHBondContact O-N 3.41Å; I411-I414 PolarHBondContact O-N 3.41Å; I411-F415 HydrophobicContact CG2-CD2 4.32Å; I411-F415 HydrophobicContact CG2-CE2 4Å; I411-F415 WeakPolarHBondContact O-CD2 3.27Å
412	L	94.6	Very high	92.3	Very high	83 Å²	83	43.7 Å²	43.7	44%	0.435	24%	0.244	S	C	.	.	H	α-helix	trans	-68.5	-39.4	-176.8	-178.9	54.8	0	0	0	113	L161 G408 T409 N410 I414 F415 V416	L161-L412 HydrophobicContact CD1-CD2 3.67Å; L161-L412 HydrophobicContact CD1-CG 4.2Å; L161-L412 HydrophobicContact CD2-CB 3.88Å; L161-L412 HydrophobicContact CD2-CD2 3.98Å; L161-L412 HydrophobicContact CD2-CG 3.85Å; L161-L412 HydrophobicContact CG-CD2 4.46Å; G408-L412 VanDerWaalsContact O-CB 3.31Å; G408-L412 WeakPolarHBondContact O-CB 3.29Å; G408-L412 PolarHBondContact O-N 3Å; T409-L412 PolarHBondContact O-N 3.34Å; N410-L412 VanDerWaalsContact C-N 3.33Å; N410-L412 PolarHBondContact O-N 3.48Å; L412-I414 VanDerWaalsContact C-N 3.3Å; L412-I414 PolarHBondContact O-N 3.28Å; L412-F415 PolarHBondContact O-N 3.38Å; L412-V416 WeakPolarHBondContact O-CG2 3.35Å; L412-V416 PolarHBondContact O-N 2.96Å
413	V	95	Very high	92.6	Very high	0 Å²	0	43.8 Å²	43.8	0%	0	24%	0.244	C	C	.	.	H	α-helix	trans	-69.6	-26	-179.3	81.2	0	0	0	0	113.3	L161 L164 Y165 V194 T409 N410 F415 V416	L161-V413 HydrophobicContact CD2-CB 4.15Å; L161-V413 WeakPolarHBondContact O-CG2 3.49Å; L164-V413 HydrophobicContact CB-CB 4.29Å; L164-V413 HydrophobicContact CB-CG1 3.95Å; L164-V413 HydrophobicContact CB-CG2 4.17Å; Y165-V413 HydrophobicContact CD2-CG2 4.3Å; V194-V413 HydrophobicContact CG1-CG1 4.39Å; V194-V413 HydrophobicContact CG2-CG1 4.38Å; T409-V413 WeakPolarHBondContact O-CB 3.43Å; T409-V413 PolarHBondContact O-N 3.4Å; N410-V413 WeakPolarHBondContact O-CG1 3.46Å; V413-F415 VanDerWaalsContact C-N 3.31Å; V413-F415 PolarHBondContact O-N 3.34Å; V413-V416 PolarHBondContact O-N 3.12Å
414	I	93.7	Very high	92.7	Very high	46 Å²	46	39 Å²	39	24%	0.236	22%	0.22	C	C	.	.	H	α-helix	trans	-61.5	-43	172.6	-69.8	164.4	0	0	0	109.9	K168 D191 V194 I195 N410 I411 L412	K168-I414 PolarHBondContact NZ-O 2.9Å; D191-I414 HydrophobicContact CB-CG1 4.16Å; D191-I414 HydrophobicContact CB-CG2 4.39Å; D191-I414 WeakPolarHBondContact OD1-CG1 3.47Å; V194-I414 HydrophobicContact CG1-CG1 4.46Å; I195-I414 HydrophobicContact CD1-CD1 3.83Å; I195-I414 HydrophobicContact CG1-CD1 4.13Å; N410-I414 WeakPolarHBondContact O-CD1 3.35Å; N410-I414 VanDerWaalsContact O-CG1 3.28Å; N410-I414 WeakPolarHBondContact O-CG1 3.47Å; N410-I414 PolarHBondContact O-N 3.02Å; I411-I414 PolarHBondContact O-N 3.41Å; L412-I414 VanDerWaalsContact C-N 3.3Å; L412-I414 PolarHBondContact O-N 3.28Å
415	F	92	Very high	92.9	Very high	160 Å²	160	38.9 Å²	38.9	70%	0.702	22%	0.215	S	C	*	.	H	α-helix	trans	-83.3	-5.9	-179.9	-64.5	-64.5	0	0	0	115.5	I411 L412 V413 P417	I411-F415 HydrophobicContact CG2-CD2 4.32Å; I411-F415 HydrophobicContact CG2-CE2 4Å; I411-F415 WeakPolarHBondContact O-CD2 3.27Å; L412-F415 PolarHBondContact O-N 3.38Å; V413-F415 VanDerWaalsContact C-N 3.31Å; V413-F415 PolarHBondContact O-N 3.34Å; F415-P417 VanDerWaalsContact O-CD 3.31Å; F415-P417 WeakPolarHBondContact O-CD 3.16Å
416	V	90.4	Very high	93.2	Very high	19 Å²	19	38.1 Å²	38.1	12%	0.115	21%	0.212	C	C	.	.			trans	-81.8	116.8	176.2	169.4	0	0	0	0	110.1	Y165 L412 V413 S418 I422	Y165-V416 HydrophobicContact CD2-CG1 4.2Å; Y165-V416 HydrophobicContact CE2-CG1 4.21Å; L412-V416 WeakPolarHBondContact O-CG2 3.35Å; L412-V416 PolarHBondContact O-N 2.96Å; V413-V416 PolarHBondContact O-N 3.12Å; V416-S418 WeakPolarHBondContact CG1-O 3.35Å; V416-I422 HydrophobicContact CG1-CD1 3.97Å; V416-I422 HydrophobicContact CG1-CG1 3.92Å; V416-I422 HydrophobicContact CG2-CG1 4.37Å
417	P	87.3	Confident	93.4	Very high	93 Å²	93	37.8 Å²	37.8	60%	0.604	21%	0.21	S	C	*	.	S	Bend	trans	-82.4	-13.9	-177.7	33.4	-36.5	0	0	0	113.8	F415 Y421	F415-P417 VanDerWaalsContact O-CD 3.31Å; F415-P417 WeakPolarHBondContact O-CD 3.16Å; P417-Y421 HydrophobicContact CG-CD2 4.06Å; P417-Y421 HydrophobicContact CG-CE2 3.9Å
418	S	90.5	Very high	93.5	Very high	13 Å²	13	35.7 Å²	35.7	9%	0.091	19%	0.192	C	C	.	.			trans	-160.4	137	176.6	-173	0	0	0	0	112.3	V416 R420 Y421	V416-S418 WeakPolarHBondContact CG1-O 3.35Å; S418-R420 PolarHBondContact O-N 3.16Å; S418-R420 VanDerWaalsContact O-N 3.13Å; S418-Y421 PolarHBondContact O-N 3.47Å; S418-Y421 VanDerWaalsContact O-N 3.16Å
419	I	92.8	Very high	93.6	Very high	0 Å²	0	34.8 Å²	34.8	0%	0	18%	0.18	C	C	.	.	H	α-helix	trans	-56.5	-27.1	175.7	-159	173.1	0	0	0	112.9	T162 Y165 P341 E342 Y421 I422 F423	T162-I419 HydrophobicContact CG2-CD1 4.12Å; T162-I419 HydrophobicContact CG2-CG1 3.85Å; Y165-I419 HydrophobicContact CD1-CB 3.86Å; Y165-I419 HydrophobicContact CD1-CD1 4.1Å; Y165-I419 HydrophobicContact CD1-CG1 4.24Å; Y165-I419 HydrophobicContact CD2-CB 4.41Å; Y165-I419 HydrophobicContact CE1-CB 3.85Å; Y165-I419 HydrophobicContact CE1-CG2 4.4Å; Y165-I419 HydrophobicContact CE2-CB 4.37Å; Y165-I419 HydrophobicContact CG-CB 4.17Å; Y165-I419 HydrophobicContact CG-CG1 4.38Å; P341-I419 HydrophobicContact CB-CG2 4.21Å; P341-I419 VanDerWaalsContact O-CG2 3.24Å; P341-I419 WeakPolarHBondContact O-CG2 3.47Å; E342-I419 HydrophobicContact CB-CG2 4.07Å; E342-I419 HydrophobicContact CG-CD1 4.45Å; I419-Y421 PolarHBondContact O-N 3.04Å; I419-I422 HydrophobicContact CG1-CD1 4.39Å; I419-I422 PolarHBondContact O-N 3.33Å; I419-F423 HydrophobicContact CB-CE2 4.39Å; I419-F423 HydrophobicContact CD1-CE1 4.5Å; I419-F423 HydrophobicContact CD1-CE2 3.81Å; I419-F423 HydrophobicContact CD1-CZ 3.64Å; I419-F423 HydrophobicContact CG1-CD2 4.22Å; I419-F423 HydrophobicContact CG1-CE1 4.46Å; I419-F423 HydrophobicContact CG1-CE2 3.7Å; I419-F423 HydrophobicContact CG1-CZ 3.84Å; I419-F423 HydrophobicContact CG2-CD2 4.39Å; I419-F423 HydrophobicContact CG2-CE2 3.98Å; I419-F423 PolarHBondContact O-N 3.46Å; I419-F423 VanDerWaalsContact O-N 3.12Å
420	R	92.2	Very high	93.8	Very high	25 Å²	25	34.6 Å²	34.6	9%	0.094	18%	0.179	C	C	.	.	H	α-helix	trans	-57.4	-33.1	178.4	81.8	-171.3	-173.1	110.3	3.8	112.7	F92 Y279 P341 S418 G424 D481	F92-R420 HydrophobicContact CE1-CB 4.47Å; Y279-R420 HydrophobicContact CD1-CB 4.47Å; Y279-R420 VanDerWaalsContact CD1-O 3.31Å; Y279-R420 WeakPolarHBondContact CD1-O 3.27Å; Y279-R420 HydrophobicContact CE1-CG 4.23Å; P341-R420 HydrophobicContact CB-CB 3.89Å; S418-R420 PolarHBondContact O-N 3.16Å; S418-R420 VanDerWaalsContact O-N 3.13Å; R420-G424 PolarHBondContact O-N 3.41Å; R420-D481 IonicContact CZ-OD2 3.93Å; R420-D481 VanDerWaalsContact CZ-OD2 3.26Å; R420-D481 IonicContact NH1-OD2 3.95Å; R420-D481 PolarHBondContact NH1-OD2 3.08Å; R420-D481 IonicContact NH2-OD2 2.93Å; R420-D481 PolarHBondContact NH2-OD2 3.19Å
421	Y	92.5	Very high	93.9	Very high	44 Å²	44	34.1 Å²	34.1	17%	0.173	18%	0.176	C	C	.	.	H	α-helix	trans	-74.5	-31.1	178.7	-58.5	-59.3	0	0	0	112.5	Y279 P417 S418 I419 L425 W482 S485	Y279-Y421 HydrophobicContact CE1-CD1 4.18Å; Y279-Y421 WeakPolarHBondContact OH-CE1 3.36Å; P417-Y421 HydrophobicContact CG-CD2 4.06Å; P417-Y421 HydrophobicContact CG-CE2 3.9Å; S418-Y421 PolarHBondContact O-N 3.47Å; S418-Y421 VanDerWaalsContact O-N 3.16Å; I419-Y421 PolarHBondContact O-N 3.04Å; Y421-L425 WeakPolarHBondContact O-CB 3.46Å; Y421-L425 PolarHBondContact O-N 3.31Å; Y421-W482 AromaticContact CD1-CD1 3.9Å; Y421-W482 HydrophobicContact CE1-CB 4.25Å; Y421-W482 AromaticContact CE1-CD1 3.59Å; Y421-W482 HydrophobicContact CE1-CG 4.31Å; Y421-W482 AromaticContact CZ-CD1 3.92Å; Y421-S485 PolarHBondContact OH-OG 3.23Å
422	I	94.9	Very high	94	Very high	10 Å²	10	29.2 Å²	29.2	5%	0.051	15%	0.151	C	C	.	.	H	α-helix	trans	-68.9	-49.5	173.9	-49.1	166	0	0	0	109.4	L161 T162 V416 I419 G424 L425 C426	L161-I422 HydrophobicContact CB-CD1 3.87Å; L161-I422 HydrophobicContact CB-CG2 4.26Å; T162-I422 HydrophobicContact CG2-CB 4.02Å; T162-I422 HydrophobicContact CG2-CD1 4.05Å; T162-I422 HydrophobicContact CG2-CG2 3.8Å; V416-I422 HydrophobicContact CG1-CD1 3.97Å; V416-I422 HydrophobicContact CG1-CG1 3.92Å; V416-I422 HydrophobicContact CG2-CG1 4.37Å; I419-I422 HydrophobicContact CG1-CD1 4.39Å; I419-I422 PolarHBondContact O-N 3.33Å; I422-G424 VanDerWaalsContact C-N 3.32Å; I422-G424 PolarHBondContact O-N 2.98Å; I422-L425 PolarHBondContact O-N 3.15Å; I422-C426 WeakPolarHBondContact O-CB 3.37Å; I422-C426 PolarHBondContact O-N 3.21Å
423	F	94.8	Very high	94.1	Very high	1 Å²	1	27.2 Å²	27.2	0%	0.004	14%	0.14	C	C	.	.	H	α-helix	trans	-59.7	-42.6	175.1	-63.3	-41.7	0	0	0	111.9	T162 P282 I283 F286 I419 G427	T162-F423 HydrophobicContact CG2-CD1 3.97Å; T162-F423 HydrophobicContact CG2-CE1 3.57Å; T162-F423 HydrophobicContact CG2-CZ 4.16Å; P282-F423 WeakPolarHBondContact CB-O 3.28Å; I283-F423 HydrophobicContact CG1-CB 3.63Å; I283-F423 HydrophobicContact CG1-CD2 4.15Å; I283-F423 HydrophobicContact CG1-CG 4.16Å; F286-F423 AromaticContact CD1-CD1 3.58Å; F286-F423 HydrophobicContact CD1-CD1 3.58Å; F286-F423 AromaticContact CD1-CE1 3.82Å; F286-F423 HydrophobicContact CD1-CE1 3.82Å; F286-F423 HydrophobicContact CD2-CD1 4.46Å; F286-F423 AromaticContact CE1-CD1 3.69Å; F286-F423 HydrophobicContact CE1-CD1 3.69Å; F286-F423 AromaticContact CE1-CE1 3.64Å; F286-F423 HydrophobicContact CE1-CE1 3.64Å; F286-F423 AromaticContact CG-CD1 4Å; F286-F423 HydrophobicContact CG-CD1 4Å; F286-F423 HydrophobicContact CZ-CD1 4.16Å; F286-F423 HydrophobicContact CZ-CE1 4.33Å; I419-F423 HydrophobicContact CB-CE2 4.39Å; I419-F423 HydrophobicContact CD1-CE1 4.5Å; I419-F423 HydrophobicContact CD1-CE2 3.81Å; I419-F423 HydrophobicContact CD1-CZ 3.64Å; I419-F423 HydrophobicContact CG1-CD2 4.22Å; I419-F423 HydrophobicContact CG1-CE1 4.46Å; I419-F423 HydrophobicContact CG1-CE2 3.7Å; I419-F423 HydrophobicContact CG1-CZ 3.84Å; I419-F423 HydrophobicContact CG2-CD2 4.39Å; I419-F423 HydrophobicContact CG2-CE2 3.98Å; I419-F423 PolarHBondContact O-N 3.46Å; I419-F423 VanDerWaalsContact O-N 3.12Å; F423-G427 WeakPolarHBondContact O-CA 3.47Å; F423-G427 PolarHBondContact O-N 2.84Å
424	G	94.1	Very high	94.2	Very high	0 Å²	0	27.2 Å²	27.2	0%	0	14%	0.14	C	C	.	.	H	α-helix	trans	-57.8	-57	175.7	0	0	0	0	0	112.5	R420 I422 A428	R420-G424 PolarHBondContact O-N 3.41Å; I422-G424 VanDerWaalsContact C-N 3.32Å; I422-G424 PolarHBondContact O-N 2.98Å; G424-A428 WeakPolarHBondContact O-CB 3.45Å; G424-A428 PolarHBondContact O-N 3.33Å
425	L	95.2	Very high	94.3	Very high	92 Å²	92	25 Å²	25	48%	0.482	13%	0.129	S	C	.	.	H	α-helix	trans	-68.3	-54.4	-175.5	-178.3	61.2	0	0	0	112.3	Y421 I422 S429 L475	Y421-L425 WeakPolarHBondContact O-CB 3.46Å; Y421-L425 PolarHBondContact O-N 3.31Å; I422-L425 PolarHBondContact O-N 3.15Å; L425-S429 WeakPolarHBondContact O-CB 3.31Å; L425-S429 PolarHBondContact O-N 2.71Å; L425-S429 VanDerWaalsContact O-N 3.1Å; L425-S429 PolarHBondContact O-OG 3.41Å; L425-L475 HydrophobicContact CD1-CD1 4.01Å
426	C	95.8	Very high	94.6	Very high	9 Å²	9	17.5 Å²	17.5	6%	0.061	10%	0.096	C	C	.	.	H	α-helix	trans	-69.4	-35.2	-177.8	-64	0	0	0	0	111.8	F286 I422 S430 A431	F286-C426 HydrophobicContact CD2-CB 3.67Å; F286-C426 HydrophobicContact CE2-CB 3.61Å; I422-C426 WeakPolarHBondContact O-CB 3.37Å; I422-C426 PolarHBondContact O-N 3.21Å; C426-S430 PolarHBondContact O-N 3.18Å; C426-S430 VanDerWaalsContact O-N 3.07Å; C426-S430 PolarHBondContact O-OG 3.42Å; C426-A431 PolarHBondContact O-N 3.09Å
427	G	95.8	Very high	94.9	Very high	0 Å²	0	17.5 Å²	17.5	0%	0	10%	0.095	C	C	.	.	I	π-helix	trans	-65.4	-49.1	174.8	0	0	0	0	0	113	P282 T285 F423 S429 V432	P282-G427 VanDerWaalsContact O-CA 3.27Å; P282-G427 WeakPolarHBondContact O-CA 3.03Å; T285-G427 PolarHBondContact OG1-O 3.05Å; F423-G427 WeakPolarHBondContact O-CA 3.47Å; F423-G427 PolarHBondContact O-N 2.84Å; G427-S429 VanDerWaalsContact C-N 3.3Å; G427-S429 PolarHBondContact O-N 2.84Å; G427-V432 WeakPolarHBondContact O-CG2 3.42Å; G427-V432 PolarHBondContact O-N 3.29Å
428	A	96.3	Very high	95.3	Very high	0 Å²	0	13.7 Å²	13.7	0%	0	7%	0.07	C	C	.	.	I	π-helix	trans	-66.8	-29.3	179.2	0	0	0	0	0	113.4	P282 G424 M471 L475	P282-A428 HydrophobicContact CG-CB 4.03Å; G424-A428 WeakPolarHBondContact O-CB 3.45Å; G424-A428 PolarHBondContact O-N 3.33Å; A428-M471 WeakPolarHBondContact O-CG 3.5Å; A428-L475 HydrophobicContact CB-CB 4.18Å; A428-L475 HydrophobicContact CB-CD1 4.32Å
429	S	96.5	Very high	95.6	Very high	18 Å²	18	13.1 Å²	13.1	13%	0.126	7%	0.065	C	C	.	.	I	π-helix	trans	-107.3	-79.7	-174.3	64.3	0	0	0	0	113.4	M154 L425 G427 A431 V432 M433	M154-S429 WeakPolarHBondContact CE-OG 3.27Å; L425-S429 WeakPolarHBondContact O-CB 3.31Å; L425-S429 PolarHBondContact O-N 2.71Å; L425-S429 VanDerWaalsContact O-N 3.1Å; L425-S429 PolarHBondContact O-OG 3.41Å; G427-S429 VanDerWaalsContact C-N 3.3Å; G427-S429 PolarHBondContact O-N 2.84Å; S429-A431 PolarHBondContact O-N 2.94Å; S429-V432 PolarHBondContact O-N 2.85Å; S429-M433 VanDerWaalsContact O-CB 3.25Å; S429-M433 WeakPolarHBondContact O-CB 3.47Å; S429-M433 PolarHBondContact O-N 3.34Å
430	S	96.1	Very high	95.7	Very high	0 Å²	0	13.1 Å²	13.1	0%	0	7%	0.065	C	C	.	.	I	π-helix	trans	-64	-41.4	-173.4	48.1	0	0	0	0	113.1	S151 Q155 C426 M433 L434	S151-S430 WeakPolarHBondContact O-CB 3.38Å; Q155-S430 PolarHBondContact OE1-OG 3Å; C426-S430 PolarHBondContact O-N 3.18Å; C426-S430 VanDerWaalsContact O-N 3.07Å; C426-S430 PolarHBondContact O-OG 3.42Å; S430-M433 PolarHBondContact O-N 3.36Å; S430-L434 VanDerWaalsContact O-CB 3.32Å; S430-L434 WeakPolarHBondContact O-CB 3.23Å; S430-L434 WeakPolarHBondContact O-CD1 3.39Å; S430-L434 VanDerWaalsContact O-CG 3.23Å; S430-L434 WeakPolarHBondContact O-CG 3.26Å; S430-L434 PolarHBondContact O-N 3.4Å
431	A	96.4	Very high	95.9	Very high	0 Å²	0	12.7 Å²	12.7	0%	0	7%	0.068	C	C	.	.	I	π-helix	trans	-67.9	-43.1	178.7	0	0	0	0	0	111.6	V289 C426 S429 M433 L434 I435	V289-A431 HydrophobicContact CB-CB 4.14Å; V289-A431 HydrophobicContact CG1-CB 4.22Å; V289-A431 HydrophobicContact CG2-CB 4.29Å; C426-A431 PolarHBondContact O-N 3.09Å; S429-A431 PolarHBondContact O-N 2.94Å; A431-M433 VanDerWaalsContact C-N 3.35Å; A431-M433 PolarHBondContact O-N 2.97Å; A431-L434 PolarHBondContact O-N 3.2Å; A431-I435 HydrophobicContact CB-CD1 4.36Å; A431-I435 VanDerWaalsContact O-CB 3.29Å; A431-I435 WeakPolarHBondContact O-CB 3.32Å; A431-I435 WeakPolarHBondContact O-CD1 3.36Å; A431-I435 VanDerWaalsContact O-CG1 3.23Å; A431-I435 WeakPolarHBondContact O-CG1 3.35Å; A431-I435 PolarHBondContact O-N 3.12Å
432	V	97.5	Very high	96	Very high	0 Å²	0	10.7 Å²	10.7	0%	0	6%	0.06	C	C	.	.	H	α-helix	trans	-64.4	-39.3	175.1	173	0	0	0	0	111.9	T285 G427 S429 L434 F436 I437 G467 V470 M471	T285-V432 HydrophobicContact CG2-CG2 4.12Å; G427-V432 WeakPolarHBondContact O-CG2 3.42Å; G427-V432 PolarHBondContact O-N 3.29Å; S429-V432 PolarHBondContact O-N 2.85Å; V432-L434 PolarHBondContact O-N 3.15Å; V432-F436 HydrophobicContact CB-CD2 4.28Å; V432-F436 HydrophobicContact CG1-CD2 3.92Å; V432-F436 HydrophobicContact CG1-CG 4.5Å; V432-F436 HydrophobicContact CG2-CD2 4.41Å; V432-F436 HydrophobicContact CG2-CE2 4.39Å; V432-F436 WeakPolarHBondContact O-CB 3.47Å; V432-F436 PolarHBondContact O-N 3.29Å; V432-I437 HydrophobicContact CG1-CD1 4.45Å; V432-I437 PolarHBondContact O-N 3.03Å; V432-G467 VanDerWaalsContact CG1-O 3.24Å; V432-G467 WeakPolarHBondContact CG1-O 3.41Å; V432-V470 HydrophobicContact CG1-CG1 4.39Å; V432-V470 HydrophobicContact CG2-CG1 3.83Å; V432-M471 HydrophobicContact CB-CB 4.47Å; V432-M471 HydrophobicContact CG1-CB 3.74Å; V432-M471 HydrophobicContact CG1-CG 4.4Å
433	M	97.1	Very high	96	Very high	41 Å²	41	10.2 Å²	10.2	20%	0.202	6%	0.057	C	C	.	.	I	π-helix	trans	-62.7	-41.5	175.7	-173.6	60.5	68.9	0	0	112	S151 S429 S430 A431 I437 L438 M471	S151-M433 WeakPolarHBondContact OG-CG 3.47Å; S429-M433 VanDerWaalsContact O-CB 3.25Å; S429-M433 WeakPolarHBondContact O-CB 3.47Å; S429-M433 PolarHBondContact O-N 3.34Å; S430-M433 PolarHBondContact O-N 3.36Å; A431-M433 VanDerWaalsContact C-N 3.35Å; A431-M433 PolarHBondContact O-N 2.97Å; M433-I437 HydrophobicContact CE-CD1 3.87Å; M433-I437 HydrophobicContact CE-CG2 4.35Å; M433-I437 PolarHBondContact O-N 3.06Å; M433-I437 HydrophobicContact SD-CB 3.67Å; M433-I437 HydrophobicContact SD-CD1 4.05Å; M433-I437 HydrophobicContact SD-CG1 4.43Å; M433-I437 HydrophobicContact SD-CG2 3.56Å; M433-I437 VanDerWaalsContact SD-CG2 3.56Å; M433-L438 HydrophobicContact CG-CD1 3.79Å; M433-L438 HydrophobicContact CG-CG 3.94Å; M433-L438 WeakPolarHBondContact O-CB 3.35Å; M433-L438 WeakPolarHBondContact O-CG 3.49Å; M433-L438 PolarHBondContact O-N 3.2Å; M433-L438 HydrophobicContact SD-CD1 4.39Å; M433-L438 HydrophobicContact SD-CD2 4.4Å; M433-L438 HydrophobicContact SD-CG 3.91Å; M433-M471 HydrophobicContact CE-SD 3.87Å
434	L	96.2	Very high	95.9	Very high	0 Å²	0	11.8 Å²	11.8	0%	0	7%	0.065	C	C	.	.	I	π-helix	trans	-78.2	-32.4	179.9	-72.4	167.9	0	0	0	114.4	Y132 I152 Q155 V289 H291 P292 S430 A431 V432 L438 P439	Y132-L434 HydrophobicContact CE1-CD2 4.45Å; Y132-L434 HydrophobicContact CE2-CD2 4.17Å; Y132-L434 PolarHBondContact OH-O 2.89Å; I152-L434 HydrophobicContact CG1-CD2 3.86Å; Q155-L434 HydrophobicContact CB-CD1 3.73Å; Q155-L434 HydrophobicContact CG-CD1 4Å; V289-L434 HydrophobicContact CG2-CB 3.88Å; V289-L434 HydrophobicContact CG2-CD1 3.92Å; H291-L434 HydrophobicContact CB-CB 4.18Å; P292-L434 HydrophobicContact CG-CD1 3.93Å; S430-L434 VanDerWaalsContact O-CB 3.32Å; S430-L434 WeakPolarHBondContact O-CB 3.23Å; S430-L434 WeakPolarHBondContact O-CD1 3.39Å; S430-L434 VanDerWaalsContact O-CG 3.23Å; S430-L434 WeakPolarHBondContact O-CG 3.26Å; S430-L434 PolarHBondContact O-N 3.4Å; A431-L434 PolarHBondContact O-N 3.2Å; V432-L434 PolarHBondContact O-N 3.15Å; L434-L438 HydrophobicContact CD2-CD1 4.24Å; L434-P439 VanDerWaalsContact O-CD 3.23Å; L434-P439 WeakPolarHBondContact O-CD 3.22Å; L434-P439 WeakPolarHBondContact O-CG 3.15Å
435	I	96.8	Very high	95.8	Very high	0 Å²	0	17.1 Å²	17.1	0%	0	9%	0.088	C	C	.	.	I	π-helix	trans	-85.7	-46.4	-179.8	-65.2	164.2	0	0	0	111.1	S116 T285 V289 A431 F463	S116-I435 WeakPolarHBondContact CB-O 3.38Å; S116-I435 PolarHBondContact OG-O 3.2Å; T285-I435 HydrophobicContact CG2-CD1 4.48Å; T285-I435 VanDerWaalsContact O-CD1 3.26Å; T285-I435 WeakPolarHBondContact O-CD1 3.44Å; V289-I435 HydrophobicContact CB-CD1 4.11Å; V289-I435 HydrophobicContact CB-CG1 4.38Å; V289-I435 HydrophobicContact CG2-CD1 4.44Å; V289-I435 HydrophobicContact CG2-CG1 4.23Å; A431-I435 HydrophobicContact CB-CD1 4.36Å; A431-I435 VanDerWaalsContact O-CB 3.29Å; A431-I435 WeakPolarHBondContact O-CB 3.32Å; A431-I435 WeakPolarHBondContact O-CD1 3.36Å; A431-I435 VanDerWaalsContact O-CG1 3.23Å; A431-I435 WeakPolarHBondContact O-CG1 3.35Å; A431-I435 PolarHBondContact O-N 3.12Å; I435-F463 WeakPolarHBondContact O-CE1 3.47Å
436	F	96.7	Very high	95.5	Very high	3 Å²	3	14.1 Å²	14.1	1%	0.013	7%	0.073	C	C	.	.	I	π-helix	trans	-104.9	-50	-169.2	-58.7	-100	0	0	0	112.7	F112 T285 V432 S440 F463 F466	F112-F436 HydrophobicContact CB-CE1 4Å; F112-F436 HydrophobicContact CB-CZ 4.31Å; F112-F436 AromaticContact CD2-CE1 3.59Å; F112-F436 HydrophobicContact CD2-CE1 3.59Å; F112-F436 HydrophobicContact CD2-CZ 4.08Å; F112-F436 HydrophobicContact CE2-CE1 4.28Å; F112-F436 HydrophobicContact CG-CE1 4.04Å; T285-F436 HydrophobicContact CG2-CE2 3.92Å; T285-F436 HydrophobicContact CG2-CZ 4.45Å; V432-F436 HydrophobicContact CB-CD2 4.28Å; V432-F436 HydrophobicContact CG1-CD2 3.92Å; V432-F436 HydrophobicContact CG1-CG 4.5Å; V432-F436 HydrophobicContact CG2-CD2 4.41Å; V432-F436 HydrophobicContact CG2-CE2 4.39Å; V432-F436 WeakPolarHBondContact O-CB 3.47Å; V432-F436 PolarHBondContact O-N 3.29Å; F436-S440 VanDerWaalsContact O-CB 3.25Å; F436-S440 WeakPolarHBondContact O-CB 3.3Å; F436-S440 PolarHBondContact O-OG 3.32Å; F436-F463 HydrophobicContact CB-CZ 4.48Å; F436-F463 AromaticContact CD1-CD2 3.86Å; F436-F463 HydrophobicContact CD1-CD2 3.86Å; F436-F463 HydrophobicContact CD1-CE1 4.44Å; F436-F463 AromaticContact CD1-CE2 3.22Å; F436-F463 HydrophobicContact CD1-CE2 3.22Å; F436-F463 AromaticContact CD1-CZ 3.56Å; F436-F463 HydrophobicContact CD1-CZ 3.56Å; F436-F463 HydrophobicContact CE1-CD2 4.39Å; F436-F463 AromaticContact CE1-CE2 3.53Å; F436-F463 HydrophobicContact CE1-CE2 3.53Å; F436-F463 HydrophobicContact CE1-CZ 4Å; F436-F463 HydrophobicContact CG-CE2 4.22Å; F436-F463 HydrophobicContact CG-CZ 4.15Å; F436-F466 AromaticContact CD1-CD1 3.86Å; F436-F466 HydrophobicContact CD1-CD1 3.86Å; F436-F466 HydrophobicContact CD1-CE1 4.27Å; F436-F466 AromaticContact CE1-CD1 3.72Å; F436-F466 HydrophobicContact CE1-CD1 3.72Å; F436-F466 AromaticContact CE1-CE1 3.67Å; F436-F466 HydrophobicContact CE1-CE1 3.67Å; F436-F466 HydrophobicContact CZ-CE1 4.4Å
437	I	97.3	Very high	95.1	Very high	18 Å²	18	13.8 Å²	13.8	9%	0.092	7%	0.07	C	C	.	.	I	π-helix	trans	-80.9	-56.9	-163.8	-58.7	175.6	0	0	0	111.2	V432 M433 A441 L464 M468 M471	V432-I437 HydrophobicContact CG1-CD1 4.45Å; V432-I437 PolarHBondContact O-N 3.03Å; M433-I437 HydrophobicContact CE-CD1 3.87Å; M433-I437 HydrophobicContact CE-CG2 4.35Å; M433-I437 PolarHBondContact O-N 3.06Å; M433-I437 HydrophobicContact SD-CB 3.67Å; M433-I437 HydrophobicContact SD-CD1 4.05Å; M433-I437 HydrophobicContact SD-CG1 4.43Å; M433-I437 HydrophobicContact SD-CG2 3.56Å; M433-I437 VanDerWaalsContact SD-CG2 3.56Å; I437-A441 VanDerWaalsContact O-CB 3.32Å; I437-A441 WeakPolarHBondContact O-CB 3.45Å; I437-A441 PolarHBondContact O-N 3.34Å; I437-L464 HydrophobicContact CB-CD1 4.2Å; I437-L464 HydrophobicContact CG2-CD1 3.69Å; I437-M468 HydrophobicContact CD1-CG 4.11Å; I437-M468 HydrophobicContact CG1-CG 4.34Å; I437-M471 HydrophobicContact CD1-CB 4.39Å; I437-M471 HydrophobicContact CD1-CE 4.41Å; I437-M471 HydrophobicContact CD1-SD 3.76Å
438	L	95.9	Very high	94.3	Very high	14 Å²	14	22.4 Å²	22.4	7%	0.073	11%	0.108	C	C	.	.	H	α-helix	trans	-64.4	-51.7	-173.6	-72.5	169.9	0	0	0	112.7	Y132 A147 M433 L434 S440 A441 L442	Y132-L438 HydrophobicContact CE1-CB 4.03Å; Y132-L438 HydrophobicContact CE1-CD1 4.02Å; Y132-L438 WeakPolarHBondContact OH-CB 3.21Å; A147-L438 HydrophobicContact CB-CD2 4.17Å; M433-L438 HydrophobicContact CG-CD1 3.79Å; M433-L438 HydrophobicContact CG-CG 3.94Å; M433-L438 WeakPolarHBondContact O-CB 3.35Å; M433-L438 WeakPolarHBondContact O-CG 3.49Å; M433-L438 PolarHBondContact O-N 3.2Å; M433-L438 HydrophobicContact SD-CD1 4.39Å; M433-L438 HydrophobicContact SD-CD2 4.4Å; M433-L438 HydrophobicContact SD-CG 3.91Å; L434-L438 HydrophobicContact CD2-CD1 4.24Å; L438-S440 VanDerWaalsContact C-N 3.29Å; L438-S440 PolarHBondContact O-N 2.87Å; L438-A441 PolarHBondContact O-N 2.97Å; L438-L442 VanDerWaalsContact O-CB 3.31Å; L438-L442 WeakPolarHBondContact O-CB 3.39Å; L438-L442 WeakPolarHBondContact O-CG 3.43Å; L438-L442 PolarHBondContact O-N 3.43Å
439	P	96.1	Very high	93	Very high	0 Å²	0	30.6 Å²	30.6	0%	0	14%	0.144	C	C	.	.	H	α-helix	trans	-62	-35.4	-178.8	-29	42.1	0	0	0	113.2	S116 L119 L120 Y132 L434 Y443	S116-P439 WeakPolarHBondContact OG-CB 3.44Å; S116-P439 VanDerWaalsContact OG-CG 3.23Å; S116-P439 WeakPolarHBondContact OG-CG 3.5Å; L119-P439 HydrophobicContact CB-CB 4.41Å; L120-P439 HydrophobicContact CB-CB 4.29Å; L120-P439 HydrophobicContact CD1-CG 4.47Å; Y132-P439 WeakPolarHBondContact OH-CD 3.15Å; Y132-P439 WeakPolarHBondContact OH-CG 3.22Å; L434-P439 VanDerWaalsContact O-CD 3.23Å; L434-P439 WeakPolarHBondContact O-CD 3.22Å; L434-P439 WeakPolarHBondContact O-CG 3.15Å; P439-Y443 VanDerWaalsContact O-CB 3.25Å; P439-Y443 WeakPolarHBondContact O-CB 3.48Å; P439-Y443 PolarHBondContact O-N 3.41Å
440	S	96	Very high	91.9	Very high	0 Å²	0	31.8 Å²	31.8	0%	0	15%	0.147	C	C	.	.	H	α-helix	trans	-66	-48.7	174	-57.5	0	0	0	0	112.5	F436 L438 L442 Y443 I444 A460 F463	F436-S440 VanDerWaalsContact O-CB 3.25Å; F436-S440 WeakPolarHBondContact O-CB 3.3Å; F436-S440 PolarHBondContact O-OG 3.32Å; L438-S440 VanDerWaalsContact C-N 3.29Å; L438-S440 PolarHBondContact O-N 2.87Å; S440-L442 PolarHBondContact O-N 2.83Å; S440-Y443 PolarHBondContact O-N 3.42Å; S440-I444 WeakPolarHBondContact O-CD1 3.22Å; S440-I444 VanDerWaalsContact O-CG1 3.27Å; S440-I444 WeakPolarHBondContact O-CG1 3.24Å; S440-I444 PolarHBondContact O-N 3.02Å; S440-A460 WeakPolarHBondContact CB-O 3.38Å; S440-F463 WeakPolarHBondContact OG-CD1 3.47Å
441	A	95.7	Very high	90.8	Very high	17 Å²	17	35.8 Å²	35.8	14%	0.14	18%	0.175	C	C	.	.	H	α-helix	trans	-63.6	-42	179.5	0	0	0	0	0	111.6	F140 I437 L438 K445 L464	F140-A441 HydrophobicContact CE2-CB 3.92Å; F140-A441 HydrophobicContact CZ-CB 3.95Å; F140-A441 WeakPolarHBondContact CZ-O 3.47Å; I437-A441 VanDerWaalsContact O-CB 3.32Å; I437-A441 WeakPolarHBondContact O-CB 3.45Å; I437-A441 PolarHBondContact O-N 3.34Å; L438-A441 PolarHBondContact O-N 2.97Å; A441-K445 VanDerWaalsContact O-CB 3.23Å; A441-K445 WeakPolarHBondContact O-CB 3.14Å; A441-K445 PolarHBondContact O-N 2.91Å; A441-L464 HydrophobicContact CB-CD1 4.49Å
442	L	94.9	Very high	89.6	Confident	1 Å²	1	41.2 Å²	41.2	1%	0.005	20%	0.202	C	C	.	.	H	α-helix	trans	-59.3	-46.4	172.1	-68.8	171.2	0	0	0	111	L120 T123 Y132 L135 A139 L438 S440 K445 L446	L120-L442 HydrophobicContact CD1-CD1 4.18Å; T123-L442 HydrophobicContact CG2-CB 4.15Å; Y132-L442 HydrophobicContact CE1-CD1 3.97Å; L135-L442 HydrophobicContact CB-CD1 4.2Å; L135-L442 HydrophobicContact CB-CD2 4.12Å; L135-L442 HydrophobicContact CD2-CD1 4.36Å; L135-L442 WeakPolarHBondContact O-CD2 3.46Å; A139-L442 HydrophobicContact CB-CD2 3.55Å; L438-L442 VanDerWaalsContact O-CB 3.31Å; L438-L442 WeakPolarHBondContact O-CB 3.39Å; L438-L442 WeakPolarHBondContact O-CG 3.43Å; L438-L442 PolarHBondContact O-N 3.43Å; S440-L442 PolarHBondContact O-N 2.83Å; L442-K445 PolarHBondContact O-N 3.44Å; L442-L446 HydrophobicContact CB-CD1 4.29Å; L442-L446 HydrophobicContact CD2-CD1 4.09Å; L442-L446 VanDerWaalsContact O-CB 3.27Å; L442-L446 WeakPolarHBondContact O-CB 3.25Å; L442-L446 WeakPolarHBondContact O-CG 3.27Å; L442-L446 PolarHBondContact O-N 3.04Å
443	Y	94.4	Very high	88.3	Confident	0 Å²	0	50 Å²	50	0%	0	24%	0.24	C	C	.	.	H	α-helix	trans	-60.8	-51.6	-179.4	-174.7	-95.3	0	0	0	112.8	L119 K122 T123 P439 S440 K445 V447 E450 Q456 K457 A460	L119-Y443 HydrophobicContact CB-CD2 4.32Å; L119-Y443 HydrophobicContact CB-CG 4.5Å; L119-Y443 HydrophobicContact CD2-CD1 4.13Å; L119-Y443 HydrophobicContact CD2-CD2 3.72Å; L119-Y443 HydrophobicContact CD2-CE1 4.41Å; L119-Y443 HydrophobicContact CD2-CE2 4.03Å; L119-Y443 HydrophobicContact CD2-CG 3.79Å; K122-Y443 HydrophobicContact CD-CE2 3.79Å; K122-Y443 HydrophobicContact CG-CE2 4.13Å; K122-Y443 PolarHBondContact NZ-OH 2.93Å; T123-Y443 HydrophobicContact CG2-CD2 4.16Å; P439-Y443 VanDerWaalsContact O-CB 3.25Å; P439-Y443 WeakPolarHBondContact O-CB 3.48Å; P439-Y443 PolarHBondContact O-N 3.41Å; S440-Y443 PolarHBondContact O-N 3.42Å; Y443-K445 PolarHBondContact O-N 3.47Å; Y443-V447 HydrophobicContact CD2-CB 4.33Å; Y443-V447 HydrophobicContact CD2-CG2 3.65Å; Y443-V447 HydrophobicContact CE2-CB 4.08Å; Y443-V447 HydrophobicContact CE2-CG1 4.17Å; Y443-V447 HydrophobicContact CE2-CG2 3.66Å; Y443-V447 HydrophobicContact CG-CG2 4.32Å; Y443-V447 WeakPolarHBondContact O-CB 3.15Å; Y443-V447 PolarHBondContact O-N 2.98Å; Y443-V447 VanDerWaalsContact O-N 3.13Å; Y443-E450 VanDerWaalsContact OH-CD 3.24Å; Y443-E450 PolarHBondContact OH-OE1 3.34Å; Y443-E450 PolarHBondContact OH-OE2 3.4Å; Y443-Q456 HydrophobicContact CE1-CB 4.4Å; Y443-Q456 PolarHBondContact OH-OE1 2.92Å; Y443-K457 HydrophobicContact CD1-CG 4.37Å; Y443-K457 HydrophobicContact CE1-CG 3.82Å; Y443-A460 HydrophobicContact CD1-CB 3.77Å; Y443-A460 HydrophobicContact CE1-CB 4.48Å; Y443-A460 HydrophobicContact CG-CB 4.5Å
444	I	93.3	Very high	87.6	Confident	35 Å²	35	49.6 Å²	49.6	18%	0.179	24%	0.241	C	C	.	.	H	α-helix	trans	-59.5	-38.1	-178.8	-65.5	161.4	0	0	0	110.9	S440 M452 A460 L464	S440-I444 WeakPolarHBondContact O-CD1 3.22Å; S440-I444 VanDerWaalsContact O-CG1 3.27Å; S440-I444 WeakPolarHBondContact O-CG1 3.24Å; S440-I444 PolarHBondContact O-N 3.02Å; I444-M452 HydrophobicContact CG2-CE 3.96Å; I444-A460 HydrophobicContact CD1-CB 4.31Å; I444-A460 HydrophobicContact CG1-CB 4.04Å; I444-L464 HydrophobicContact CD1-CD2 4.11Å
445	K	91.4	Very high	87	Confident	111 Å²	111	55.6 Å²	55.6	48%	0.483	28%	0.277	S	S	.	.	H	α-helix	trans	-84.2	-41.4	-173.8	-171.6	64.8	169.8	-172.4	0	114.3	A139 F140 A441 L442 Y443	A139-K445 HydrophobicContact CB-CB 4.33Å; A139-K445 HydrophobicContact CB-CG 4Å; A139-K445 WeakPolarHBondContact O-CE 3.1Å; A139-K445 VanDerWaalsContact O-CG 3.3Å; A139-K445 WeakPolarHBondContact O-CG 3.1Å; F140-K445 HydrophobicContact CD1-CG 4.43Å; F140-K445 HydrophobicContact CE1-CB 4.24Å; F140-K445 HydrophobicContact CE1-CD 4.05Å; F140-K445 HydrophobicContact CE1-CG 3.94Å; F140-K445 HydrophobicContact CE2-CB 4.27Å; F140-K445 HydrophobicContact CE2-CG 4.39Å; F140-K445 HydrophobicContact CZ-CB 3.76Å; F140-K445 HydrophobicContact CZ-CD 4.44Å; F140-K445 HydrophobicContact CZ-CG 3.91Å; A441-K445 VanDerWaalsContact O-CB 3.23Å; A441-K445 WeakPolarHBondContact O-CB 3.14Å; A441-K445 PolarHBondContact O-N 2.91Å; L442-K445 PolarHBondContact O-N 3.44Å; Y443-K445 PolarHBondContact O-N 3.47Å
446	L	89.7	Confident	86.5	Confident	30 Å²	30	59.8 Å²	59.8	16%	0.157	30%	0.297	C	S	.	.	H	α-helix	trans	-89.1	-39.2	-173.5	-66.6	169.2	0	0	0	112.8	T123 A127 L135 K138 A139 L442 K448	T123-L446 HydrophobicContact CG2-CB 4.5Å; T123-L446 HydrophobicContact CG2-CD1 4.47Å; A127-L446 HydrophobicContact CB-CD1 3.99Å; A127-L446 HydrophobicContact CB-CD2 4.28Å; L135-L446 HydrophobicContact CG-CD1 4.14Å; K138-L446 HydrophobicContact CB-CD2 4.1Å; A139-L446 HydrophobicContact CB-CD1 4.06Å; A139-L446 HydrophobicContact CB-CD2 4Å; A139-L446 HydrophobicContact CB-CG 3.87Å; L442-L446 HydrophobicContact CB-CD1 4.29Å; L442-L446 HydrophobicContact CD2-CD1 4.09Å; L442-L446 VanDerWaalsContact O-CB 3.27Å; L442-L446 WeakPolarHBondContact O-CB 3.25Å; L442-L446 WeakPolarHBondContact O-CG 3.27Å; L442-L446 PolarHBondContact O-N 3.04Å; L446-K448 VanDerWaalsContact C-N 3.28Å; L446-K448 PolarHBondContact O-N 3.42Å
447	V	87.7	Confident	86	Confident	1 Å²	1	60 Å²	60	1%	0.006	30%	0.298	C	S	.	.			trans	-80.1	76	-175.4	-173.4	0	0	0	0	110.3	T123 E126 Y443 K449 K457	T123-V447 HydrophobicContact CG2-CG2 4.01Å; E126-V447 HydrophobicContact CG-CG2 4.47Å; Y443-V447 HydrophobicContact CD2-CB 4.33Å; Y443-V447 HydrophobicContact CD2-CG2 3.65Å; Y443-V447 HydrophobicContact CE2-CB 4.08Å; Y443-V447 HydrophobicContact CE2-CG1 4.17Å; Y443-V447 HydrophobicContact CE2-CG2 3.66Å; Y443-V447 HydrophobicContact CG-CG2 4.32Å; Y443-V447 WeakPolarHBondContact O-CB 3.15Å; Y443-V447 PolarHBondContact O-N 2.98Å; Y443-V447 VanDerWaalsContact O-N 3.13Å; V447-K449 VanDerWaalsContact C-N 3.27Å; V447-K449 PolarHBondContact O-N 3.11Å; V447-K457 WeakPolarHBondContact O-CE 3.3Å; V447-K457 PolarHBondContact O-NZ 2.99Å
448	K	78.3	Confident	85.7	Confident	181 Å²	181	63 Å²	63	79%	0.787	31%	0.313	S	S	*	.	T	Hydrogen-bonded Turn	trans	-69.7	-21.5	-178	-67.5	-179.9	-176.5	175.9	0	113.9	L446 E450	L446-K448 VanDerWaalsContact C-N 3.28Å; L446-K448 PolarHBondContact O-N 3.42Å; K448-E450 PolarHBondContact O-N 2.9Å
449	K	69.3	Low	85.5	Confident	173 Å²	173	63.6 Å²	63.6	75%	0.752	32%	0.323	S	S	*	.	T	Hydrogen-bonded Turn	trans	-63.3	-19.8	-175.7	-166.1	170.9	-178.1	174.6	0	114.5	V447	V447-K449 VanDerWaalsContact C-N 3.27Å; V447-K449 PolarHBondContact O-N 3.11Å
450	E	73.6	Confident	85.4	Confident	42 Å²	42	63.6 Å²	63.6	20%	0.196	32%	0.323	C	S	.	.	S	Bend	trans	-105.7	134.2	177.6	-71	179	-161	0	0	112.2	K122 Y443 K448 S454 Q456 K457	K122-E450 IonicContact NZ-OE1 3.87Å; K122-E450 PolarHBondContact NZ-OE1 2.93Å; Y443-E450 VanDerWaalsContact OH-CD 3.24Å; Y443-E450 PolarHBondContact OH-OE1 3.34Å; Y443-E450 PolarHBondContact OH-OE2 3.4Å; K448-E450 PolarHBondContact O-N 2.9Å; E450-S454 PolarHBondContact OE2-OG 2.91Å; E450-Q456 PolarHBondContact OE1-OE1 2.59Å; E450-K457 HydrophobicContact CB-CD 4.39Å; E450-K457 WeakPolarHBondContact O-CE 3.46Å; E450-K457 PolarHBondContact O-NZ 3.24Å
451	S	72.1	Confident	85.3	Confident	84 Å²	84	66 Å²	66	59%	0.587	34%	0.338	S	S	*	.			trans	-56.4	146	170.4	176.9	0	0	0	0	111.4	K453 S454	S451-K453 PolarHBondContact O-N 3.43Å; S451-K453 VanDerWaalsContact O-N 3.08Å; S451-K453 PolarHBondContact OG-N 3.09Å; S451-S454 WeakPolarHBondContact O-CB 3.48Å; S451-S454 PolarHBondContact O-N 2.97Å
452	M	71.7	Confident	85.2	Confident	115 Å²	115	71.1 Å²	71.1	57%	0.567	36%	0.36	S	S	*	.	T	Hydrogen-bonded Turn	trans	-60.8	-18	176.1	-64.2	-60.8	-67.4	0	0	113.4	I444 S454 K457	I444-M452 HydrophobicContact CG2-CE 3.96Å; M452-S454 VanDerWaalsContact C-N 3.33Å; M452-K457 HydrophobicContact SD-CD 3.79Å
453	K	69.6	Low	85.3	Confident	184 Å²	184	71.5 Å²	71.5	80%	0.8	36%	0.362	S	S	*	.	T	Hydrogen-bonded Turn	trans	-85.8	3.2	172.3	-60.5	-173.1	179	-175.7	0	113.9	S451	S451-K453 PolarHBondContact O-N 3.43Å; S451-K453 VanDerWaalsContact O-N 3.08Å; S451-K453 PolarHBondContact OG-N 3.09Å
454	S	82.4	Confident	85.4	Confident	32 Å²	32	73.1 Å²	73.1	22%	0.224	37%	0.37	C	S	.	.	S	Bend	trans	-62.9	135.2	173.5	172.6	0	0	0	0	110.6	E450 S451 M452 Q456 K457 I458	E450-S454 PolarHBondContact OE2-OG 2.91Å; S451-S454 WeakPolarHBondContact O-CB 3.48Å; S451-S454 PolarHBondContact O-N 2.97Å; M452-S454 VanDerWaalsContact C-N 3.33Å; S454-Q456 PolarHBondContact O-N 3.35Å; S454-Q456 VanDerWaalsContact O-N 3.13Å; S454-Q456 PolarHBondContact OG-N 3.29Å; S454-K457 PolarHBondContact O-N 3.04Å; S454-I458 WeakPolarHBondContact O-CG1 3.36Å; S454-I458 PolarHBondContact O-N 3Å
455	V	85.1	Confident	85.6	Confident	126 Å²	126	75.8 Å²	75.8	76%	0.764	38%	0.384	S	S	*	.	H	α-helix	trans	-52.7	-35.3	174.2	-178.9	0	0	0	0	111.3	G459	V455-G459 PolarHBondContact O-N 3.39Å
456	Q	85.3	Confident	85.8	Confident	88 Å²	88	74.9 Å²	74.9	41%	0.411	38%	0.38	S	S	.	.	H	α-helix	trans	-70.6	-33.4	179	-58.4	-170.6	12.7	0	0	112.7	Y443 E450 S454 A460	Y443-Q456 HydrophobicContact CE1-CB 4.4Å; Y443-Q456 PolarHBondContact OH-OE1 2.92Å; E450-Q456 PolarHBondContact OE1-OE1 2.59Å; S454-Q456 PolarHBondContact O-N 3.35Å; S454-Q456 VanDerWaalsContact O-N 3.13Å; S454-Q456 PolarHBondContact OG-N 3.29Å; Q456-A460 WeakPolarHBondContact O-CB 3.35Å; Q456-A460 PolarHBondContact O-N 3.39Å
457	K	87.3	Confident	86.1	Confident	8 Å²	8	73.5 Å²	73.5	4%	0.035	37%	0.373	C	S	.	.	H	α-helix	trans	-78.5	-35	174.6	-77.9	-168.4	170	179.1	0	112.9	Y443 V447 E450 M452 S454 T461	Y443-K457 HydrophobicContact CD1-CG 4.37Å; Y443-K457 HydrophobicContact CE1-CG 3.82Å; V447-K457 WeakPolarHBondContact O-CE 3.3Å; V447-K457 PolarHBondContact O-NZ 2.99Å; E450-K457 HydrophobicContact CB-CD 4.39Å; E450-K457 WeakPolarHBondContact O-CE 3.46Å; E450-K457 PolarHBondContact O-NZ 3.24Å; M452-K457 HydrophobicContact SD-CD 3.79Å; S454-K457 PolarHBondContact O-N 3.04Å; K457-T461 WeakPolarHBondContact O-CB 3.49Å; K457-T461 PolarHBondContact O-N 2.93Å; K457-T461 PolarHBondContact O-OG1 3.02Å
458	I	89.8	Confident	86.5	Confident	80 Å²	80	77.8 Å²	77.8	41%	0.41	39%	0.394	S	S	.	.	H	α-helix	trans	-62.8	-46.3	170.8	-64.1	167.7	0	0	0	109.4	S454 T461 M462	S454-I458 WeakPolarHBondContact O-CG1 3.36Å; S454-I458 PolarHBondContact O-N 3Å; I458-T461 PolarHBondContact O-N 3.47Å; I458-M462 WeakPolarHBondContact O-CG 3.33Å; I458-M462 PolarHBondContact O-N 3.19Å
459	G	92.3	Very high	87.4	Confident	27 Å²	27	71.6 Å²	71.6	28%	0.278	38%	0.377	S	S	.	.	H	α-helix	trans	-56.4	-52.1	173.8	0	0	0	0	0	112.8	V455 T461 M462 F463	V455-G459 PolarHBondContact O-N 3.39Å; G459-T461 VanDerWaalsContact C-N 3.27Å; G459-T461 PolarHBondContact O-N 3.08Å; G459-M462 PolarHBondContact O-N 3.13Å; G459-F463 VanDerWaalsContact O-CB 3.32Å; G459-F463 WeakPolarHBondContact O-CB 3.44Å; G459-F463 PolarHBondContact O-N 3.2Å
460	A	92.9	Very high	88.7	Confident	0 Å²	0	64.3 Å²	64.3	0%	0	35%	0.347	C	S	.	.	H	α-helix	trans	-60.7	-34.1	175.9	0	0	0	0	0	112.9	Y115 L119 S440 Y443 I444 Q456 F463 L464	Y115-A460 PolarHBondContact OH-N 3.29Å; L119-A460 HydrophobicContact CD1-CB 4.15Å; S440-A460 WeakPolarHBondContact CB-O 3.38Å; Y443-A460 HydrophobicContact CD1-CB 3.77Å; Y443-A460 HydrophobicContact CE1-CB 4.48Å; Y443-A460 HydrophobicContact CG-CB 4.5Å; I444-A460 HydrophobicContact CD1-CB 4.31Å; I444-A460 HydrophobicContact CG1-CB 4.04Å; Q456-A460 WeakPolarHBondContact O-CB 3.35Å; Q456-A460 PolarHBondContact O-N 3.39Å; A460-F463 PolarHBondContact O-N 3.22Å; A460-L464 WeakPolarHBondContact O-CB 3.48Å; A460-L464 PolarHBondContact O-N 3.3Å
461	T	94.1	Very high	89.7	Confident	51 Å²	51	65 Å²	65	31%	0.313	35%	0.351	S	S	.	.	H	α-helix	trans	-70.3	-42.1	177.3	-54.5	0	0	0	0	111.5	K457 I458 G459 F463 L464 I465	K457-T461 WeakPolarHBondContact O-CB 3.49Å; K457-T461 PolarHBondContact O-N 2.93Å; K457-T461 PolarHBondContact O-OG1 3.02Å; I458-T461 PolarHBondContact O-N 3.47Å; G459-T461 VanDerWaalsContact C-N 3.27Å; G459-T461 PolarHBondContact O-N 3.08Å; T461-F463 VanDerWaalsContact C-N 3.34Å; T461-L464 PolarHBondContact O-N 3.32Å; T461-I465 HydrophobicContact CG2-CD1 4.18Å; T461-I465 VanDerWaalsContact O-CG1 3.31Å; T461-I465 WeakPolarHBondContact O-CG1 3.43Å; T461-I465 PolarHBondContact O-N 3.17Å
462	M	94.9	Very high	90.9	Very high	124 Å²	124	68 Å²	68	61%	0.611	35%	0.353	S	S	*	.	H	α-helix	trans	-65.3	-38.8	173.2	-68.2	-61.3	-174.6	0	0	111.7	I458 G459 I465 F466	I458-M462 WeakPolarHBondContact O-CG 3.33Å; I458-M462 PolarHBondContact O-N 3.19Å; G459-M462 PolarHBondContact O-N 3.13Å; M462-I465 PolarHBondContact O-N 3.18Å; M462-F466 WeakPolarHBondContact O-CB 3.1Å; M462-F466 PolarHBondContact O-N 3.43Å
463	F	96	Very high	91.9	Very high	10 Å²	10	67.4 Å²	67.4	4%	0.044	36%	0.356	C	S	.	.	H	α-helix	trans	-66.2	-37.2	177.7	-166.8	-130.4	0	0	0	112.2	F112 Y115 L119 I435 F436 S440 G459 A460 T461 G467	F112-F463 HydrophobicContact CB-CE2 3.63Å; F112-F463 HydrophobicContact CB-CZ 3.87Å; F112-F463 HydrophobicContact CD1-CD2 4.25Å; F112-F463 AromaticContact CD1-CE2 3.68Å; F112-F463 HydrophobicContact CD1-CE2 3.68Å; F112-F463 HydrophobicContact CD2-CE2 4.25Å; F112-F463 HydrophobicContact CE1-CE2 4.37Å; F112-F463 AromaticContact CG-CE2 3.61Å; F112-F463 HydrophobicContact CG-CE2 3.61Å; F112-F463 HydrophobicContact CG-CZ 4.35Å; F112-F463 WeakPolarHBondContact O-CZ 3.41Å; Y115-F463 AromaticContact CD1-CD1 3.72Å; Y115-F463 HydrophobicContact CD1-CD1 3.72Å; Y115-F463 HydrophobicContact CD1-CD2 4.39Å; Y115-F463 AromaticContact CD1-CE1 3.86Å; Y115-F463 HydrophobicContact CD1-CE1 3.86Å; Y115-F463 HydrophobicContact CD1-CE2 4.48Å; Y115-F463 HydrophobicContact CD1-CG 4.04Å; Y115-F463 HydrophobicContact CD1-CZ 4.25Å; Y115-F463 HydrophobicContact CE1-CB 4.11Å; Y115-F463 AromaticContact CE1-CD1 3.71Å; Y115-F463 HydrophobicContact CE1-CD1 3.71Å; Y115-F463 HydrophobicContact CE1-CE1 4.31Å; Y115-F463 AromaticContact CE1-CG 3.91Å; Y115-F463 HydrophobicContact CE1-CG 3.91Å; L119-F463 HydrophobicContact CD1-CD1 4.25Å; I435-F463 WeakPolarHBondContact O-CE1 3.47Å; F436-F463 HydrophobicContact CB-CZ 4.48Å; F436-F463 AromaticContact CD1-CD2 3.86Å; F436-F463 HydrophobicContact CD1-CD2 3.86Å; F436-F463 HydrophobicContact CD1-CE1 4.44Å; F436-F463 AromaticContact CD1-CE2 3.22Å; F436-F463 HydrophobicContact CD1-CE2 3.22Å; F436-F463 AromaticContact CD1-CZ 3.56Å; F436-F463 HydrophobicContact CD1-CZ 3.56Å; F436-F463 HydrophobicContact CE1-CD2 4.39Å; F436-F463 AromaticContact CE1-CE2 3.53Å; F436-F463 HydrophobicContact CE1-CE2 3.53Å; F436-F463 HydrophobicContact CE1-CZ 4Å; F436-F463 HydrophobicContact CG-CE2 4.22Å; F436-F463 HydrophobicContact CG-CZ 4.15Å; S440-F463 WeakPolarHBondContact OG-CD1 3.47Å; G459-F463 VanDerWaalsContact O-CB 3.32Å; G459-F463 WeakPolarHBondContact O-CB 3.44Å; G459-F463 PolarHBondContact O-N 3.2Å; A460-F463 PolarHBondContact O-N 3.22Å; T461-F463 VanDerWaalsContact C-N 3.34Å; F463-G467 PolarHBondContact O-N 2.93Å
464	L	96.9	Very high	93.1	Very high	33 Å²	33	59.1 Å²	59.1	17%	0.173	32%	0.321	C	S	.	.	H	α-helix	trans	-62	-48.3	170	177.4	58.8	0	0	0	112.4	I437 A441 I444 A460 T461 G467 M468	I437-L464 HydrophobicContact CB-CD1 4.2Å; I437-L464 HydrophobicContact CG2-CD1 3.69Å; A441-L464 HydrophobicContact CB-CD1 4.49Å; I444-L464 HydrophobicContact CD1-CD2 4.11Å; A460-L464 WeakPolarHBondContact O-CB 3.48Å; A460-L464 PolarHBondContact O-N 3.3Å; T461-L464 PolarHBondContact O-N 3.32Å; L464-G467 PolarHBondContact O-N 2.97Å; L464-M468 HydrophobicContact CG-CE 4.29Å; L464-M468 WeakPolarHBondContact O-CG 3.33Å; L464-M468 PolarHBondContact O-N 2.96Å
465	I	96.8	Very high	93.6	Very high	92 Å²	92	60.1 Å²	60.1	47%	0.472	32%	0.324	S	S	.	.	H	α-helix	trans	-63.5	-45.5	179.5	-67.9	163.9	0	0	0	110.7	T461 M462 G467 M468 A469	T461-I465 HydrophobicContact CG2-CD1 4.18Å; T461-I465 VanDerWaalsContact O-CG1 3.31Å; T461-I465 WeakPolarHBondContact O-CG1 3.43Å; T461-I465 PolarHBondContact O-N 3.17Å; M462-I465 PolarHBondContact O-N 3.18Å; I465-G467 VanDerWaalsContact C-N 3.33Å; I465-G467 PolarHBondContact O-N 2.99Å; I465-M468 HydrophobicContact CG1-CE 4.25Å; I465-M468 PolarHBondContact O-N 3.49Å; I465-A469 PolarHBondContact O-N 2.95Å
466	F	96.3	Very high	94	Very high	92 Å²	92	56.7 Å²	56.7	40%	0.404	31%	0.306	S	S	.	.	H	α-helix	trans	-59.3	-43.7	174.2	-178	-99.4	0	0	0	111.6	F112 F436 M462 M468 A469 V470	F112-F466 HydrophobicContact CD2-CE1 4.02Å; F112-F466 HydrophobicContact CE2-CD1 4.07Å; F112-F466 AromaticContact CE2-CE1 3.41Å; F112-F466 HydrophobicContact CE2-CE1 3.41Å; F112-F466 VanDerWaalsContact CE2-CE1 3.41Å; F112-F466 AromaticContact CE2-CZ 3.87Å; F112-F466 HydrophobicContact CE2-CZ 3.87Å; F112-F466 HydrophobicContact CZ-CE1 4.18Å; F436-F466 AromaticContact CD1-CD1 3.86Å; F436-F466 HydrophobicContact CD1-CD1 3.86Å; F436-F466 HydrophobicContact CD1-CE1 4.27Å; F436-F466 AromaticContact CE1-CD1 3.72Å; F436-F466 HydrophobicContact CE1-CD1 3.72Å; F436-F466 AromaticContact CE1-CE1 3.67Å; F436-F466 HydrophobicContact CE1-CE1 3.67Å; F436-F466 HydrophobicContact CZ-CE1 4.4Å; M462-F466 WeakPolarHBondContact O-CB 3.1Å; M462-F466 PolarHBondContact O-N 3.43Å; F466-M468 PolarHBondContact O-N 3.28Å; F466-A469 PolarHBondContact O-N 2.91Å; F466-V470 HydrophobicContact CD1-CG2 3.97Å; F466-V470 HydrophobicContact CD2-CG2 4.46Å; F466-V470 HydrophobicContact CE1-CG2 3.52Å; F466-V470 HydrophobicContact CE2-CG2 4.07Å; F466-V470 HydrophobicContact CG-CG2 4.41Å; F466-V470 HydrophobicContact CZ-CG2 3.58Å; F466-V470 WeakPolarHBondContact O-CG2 3.45Å; F466-V470 PolarHBondContact O-N 3.07Å
467	G	96.3	Very high	94.3	Very high	0 Å²	0	53.5 Å²	53.5	0%	0	30%	0.296	C	S	.	.	H	α-helix	trans	-56.7	-45.8	174.5	0	0	0	0	0	113.8	V432 F463 L464 I465 V470 M471	V432-G467 VanDerWaalsContact CG1-O 3.24Å; V432-G467 WeakPolarHBondContact CG1-O 3.41Å; F463-G467 PolarHBondContact O-N 2.93Å; L464-G467 PolarHBondContact O-N 2.97Å; I465-G467 VanDerWaalsContact C-N 3.33Å; I465-G467 PolarHBondContact O-N 2.99Å; G467-V470 PolarHBondContact O-N 3.42Å; G467-M471 WeakPolarHBondContact O-CB 3.46Å; G467-M471 PolarHBondContact O-N 3.31Å
468	M	96.7	Very high	94.4	Very high	91 Å²	91	53.5 Å²	53.5	45%	0.448	30%	0.296	S	S	.	.	H	α-helix	trans	-64.8	-39.4	176.7	-67.2	-175.4	-63.8	0	0	112.2	I437 L464 I465 F466 M471 F472	I437-M468 HydrophobicContact CD1-CG 4.11Å; I437-M468 HydrophobicContact CG1-CG 4.34Å; L464-M468 HydrophobicContact CG-CE 4.29Å; L464-M468 WeakPolarHBondContact O-CG 3.33Å; L464-M468 PolarHBondContact O-N 2.96Å; I465-M468 HydrophobicContact CG1-CE 4.25Å; I465-M468 PolarHBondContact O-N 3.49Å; F466-M468 PolarHBondContact O-N 3.28Å; M468-M471 PolarHBondContact O-N 3.22Å; M468-F472 PolarHBondContact O-N 2.67Å; M468-F472 VanDerWaalsContact O-N 3.07Å
469	A	96.4	Very high	94.5	Very high	51 Å²	51	53.4 Å²	53.4	42%	0.421	30%	0.296	S	S	.	.	H	α-helix	trans	-65.1	-45.8	175.6	0	0	0	0	0	112.1	I465 F466 M471 F472 V473	I465-A469 PolarHBondContact O-N 2.95Å; F466-A469 PolarHBondContact O-N 2.91Å; A469-M471 PolarHBondContact O-N 3.3Å; A469-F472 PolarHBondContact O-N 2.96Å; A469-V473 WeakPolarHBondContact O-CB 3.35Å; A469-V473 WeakPolarHBondContact O-CG2 3.47Å; A469-V473 PolarHBondContact O-N 3.19Å
470	V	95.4	Very high	94.3	Very high	20 Å²	20	59.2 Å²	59.2	12%	0.121	31%	0.311	C	S	.	.	H	α-helix	trans	-61.6	-42.7	175.9	171.2	0	0	0	0	111.3	V281 V432 F466 G467 S474	V281-V470 HydrophobicContact CG1-CG1 3.86Å; V432-V470 HydrophobicContact CG1-CG1 4.39Å; V432-V470 HydrophobicContact CG2-CG1 3.83Å; F466-V470 HydrophobicContact CD1-CG2 3.97Å; F466-V470 HydrophobicContact CD2-CG2 4.46Å; F466-V470 HydrophobicContact CE1-CG2 3.52Å; F466-V470 HydrophobicContact CE2-CG2 4.07Å; F466-V470 HydrophobicContact CG-CG2 4.41Å; F466-V470 HydrophobicContact CZ-CG2 3.58Å; F466-V470 WeakPolarHBondContact O-CG2 3.45Å; F466-V470 PolarHBondContact O-N 3.07Å; G467-V470 PolarHBondContact O-N 3.42Å; V470-S474 WeakPolarHBondContact O-CB 3.23Å; V470-S474 PolarHBondContact O-N 2.9Å; V470-S474 PolarHBondContact O-OG 2.97Å
471	M	96.1	Very high	94	Very high	57 Å²	57	59.6 Å²	59.6	28%	0.281	31%	0.313	S	S	.	.	H	α-helix	trans	-58.8	-48.8	177	-167.8	-178	73.1	0	0	110.9	A428 V432 M433 I437 G467 M468 A469 L475	A428-M471 WeakPolarHBondContact O-CG 3.5Å; V432-M471 HydrophobicContact CB-CB 4.47Å; V432-M471 HydrophobicContact CG1-CB 3.74Å; V432-M471 HydrophobicContact CG1-CG 4.4Å; M433-M471 HydrophobicContact CE-SD 3.87Å; I437-M471 HydrophobicContact CD1-CB 4.39Å; I437-M471 HydrophobicContact CD1-CE 4.41Å; I437-M471 HydrophobicContact CD1-SD 3.76Å; G467-M471 WeakPolarHBondContact O-CB 3.46Å; G467-M471 PolarHBondContact O-N 3.31Å; M468-M471 PolarHBondContact O-N 3.22Å; A469-M471 PolarHBondContact O-N 3.3Å; M471-L475 WeakPolarHBondContact O-CB 3.34Å; M471-L475 PolarHBondContact O-N 3.04Å
472	F	95.8	Very high	93.5	Very high	147 Å²	147	62.6 Å²	62.6	65%	0.645	32%	0.318	S	S	*	.	H	α-helix	trans	-65.8	-49.7	-179	-176.2	-97.8	0	0	0	112.5	M468 A469 S476	M468-F472 PolarHBondContact O-N 2.67Å; M468-F472 VanDerWaalsContact O-N 3.07Å; A469-F472 PolarHBondContact O-N 2.96Å; F472-S476 VanDerWaalsContact O-CB 3.27Å; F472-S476 WeakPolarHBondContact O-CB 3.36Å; F472-S476 PolarHBondContact O-N 2.64Å; F472-S476 PolarHBondContact O-OG 3.04Å
473	V	94.4	Very high	93.1	Very high	102 Å²	102	62.2 Å²	62.2	62%	0.618	32%	0.317	S	S	*	.	H	α-helix	trans	-64.5	-47.2	-178.6	172.2	0	0	0	0	111.2	A469 S476 G477	A469-V473 WeakPolarHBondContact O-CB 3.35Å; A469-V473 WeakPolarHBondContact O-CG2 3.47Å; A469-V473 PolarHBondContact O-N 3.19Å; V473-S476 PolarHBondContact O-N 3.23Å; V473-G477 PolarHBondContact O-N 3.03Å
474	S	93.9	Very high	92.4	Very high	10 Å²	10	69.6 Å²	69.6	7%	0.07	34%	0.344	C	S	.	.	H	α-helix	trans	-68.5	-41.5	-177.5	-50	0	0	0	0	111.9	V470 G477 V478	V470-S474 WeakPolarHBondContact O-CB 3.23Å; V470-S474 PolarHBondContact O-N 2.9Å; V470-S474 PolarHBondContact O-OG 2.97Å; S474-G477 PolarHBondContact O-N 2.9Å; S474-V478 WeakPolarHBondContact O-CG2 3.3Å; S474-V478 PolarHBondContact O-N 2.81Å
475	L	93.6	Very high	91.4	Very high	53 Å²	53	68.8 Å²	68.8	28%	0.277	34%	0.341	S	S	.	.	H	α-helix	trans	-67.2	-40.9	178.7	-172.2	65.6	0	0	0	111.1	L425 A428 M471 V478 I479	L425-L475 HydrophobicContact CD1-CD1 4.01Å; A428-L475 HydrophobicContact CB-CB 4.18Å; A428-L475 HydrophobicContact CB-CD1 4.32Å; M471-L475 WeakPolarHBondContact O-CB 3.34Å; M471-L475 PolarHBondContact O-N 3.04Å; L475-V478 PolarHBondContact O-N 3.4Å; L475-I479 HydrophobicContact CD1-CD1 4.24Å; L475-I479 HydrophobicContact CG-CD1 3.91Å; L475-I479 WeakPolarHBondContact O-CB 3.44Å; L475-I479 VanDerWaalsContact O-CG1 3.25Å; L475-I479 WeakPolarHBondContact O-CG1 3.35Å; L475-I479 PolarHBondContact O-N 2.73Å
476	S	93.1	Very high	90	Very high	55 Å²	55	71.6 Å²	71.6	39%	0.385	35%	0.346	S	S	.	.	H	α-helix	trans	-63	-42.3	175.3	-57.6	0	0	0	0	111.9	F472 V473 I479 Y480	F472-S476 VanDerWaalsContact O-CB 3.27Å; F472-S476 WeakPolarHBondContact O-CB 3.36Å; F472-S476 PolarHBondContact O-N 2.64Å; F472-S476 PolarHBondContact O-OG 3.04Å; V473-S476 PolarHBondContact O-N 3.23Å; S476-I479 PolarHBondContact O-N 3.05Å; S476-Y480 VanDerWaalsContact O-CB 3.31Å; S476-Y480 WeakPolarHBondContact O-CB 3.4Å; S476-Y480 PolarHBondContact O-N 3.32Å
477	G	91.3	Very high	88.7	Confident	20 Å²	20	70.8 Å²	70.8	21%	0.206	35%	0.348	C	S	.	.	H	α-helix	trans	-64.6	-43.4	177.2	0	0	0	0	0	113.5	V473 S474 Y480 D481	V473-G477 PolarHBondContact O-N 3.03Å; S474-G477 PolarHBondContact O-N 2.9Å; G477-Y480 PolarHBondContact O-N 3.1Å; G477-D481 PolarHBondContact O-N 3.01Å
478	V	90.4	Very high	87	Confident	8 Å²	8	73.2 Å²	73.2	5%	0.048	37%	0.366	C	S	.	.	H	α-helix	trans	-65.3	-42.2	176.1	170.2	0	0	0	0	111.5	Y279 P282 S474 L475 W482	Y279-V478 HydrophobicContact CD1-CG2 4.03Å; Y279-V478 HydrophobicContact CE1-CB 4.49Å; Y279-V478 HydrophobicContact CE1-CG1 3.97Å; Y279-V478 HydrophobicContact CE1-CG2 4.09Å; Y279-V478 HydrophobicContact CG-CG2 4.45Å; P282-V478 HydrophobicContact CG-CG2 4.1Å; S474-V478 WeakPolarHBondContact O-CG2 3.3Å; S474-V478 PolarHBondContact O-N 2.81Å; L475-V478 PolarHBondContact O-N 3.4Å; V478-W482 WeakPolarHBondContact O-CB 3.3Å; V478-W482 PolarHBondContact O-N 2.8Å
479	I	90.2	Very high	85.1	Confident	78 Å²	78	74.8 Å²	74.8	40%	0.4	38%	0.376	S	S	.	.	H	α-helix	trans	-64.4	-41.2	175.7	-69.9	168.9	0	0	0	110.7	L475 S476 W482 M483	L475-I479 HydrophobicContact CD1-CD1 4.24Å; L475-I479 HydrophobicContact CG-CD1 3.91Å; L475-I479 WeakPolarHBondContact O-CB 3.44Å; L475-I479 VanDerWaalsContact O-CG1 3.25Å; L475-I479 WeakPolarHBondContact O-CG1 3.35Å; L475-I479 PolarHBondContact O-N 2.73Å; S476-I479 PolarHBondContact O-N 3.05Å; I479-W482 PolarHBondContact O-N 2.84Å; I479-M483 HydrophobicContact CG2-CG 4.34Å; I479-M483 HydrophobicContact CG2-SD 3.91Å; I479-M483 WeakPolarHBondContact O-CB 3.5Å; I479-M483 WeakPolarHBondContact O-CG 3.48Å; I479-M483 PolarHBondContact O-N 3.37Å
480	Y	89.4	Confident	82.9	Confident	150 Å²	150	80 Å²	80	59%	0.588	39%	0.392	S	S	*	.	H	α-helix	trans	-62.4	-49.6	178.6	-177	-89.5	0	0	0	112.4	S476 G477 W482 M483 W484	S476-Y480 VanDerWaalsContact O-CB 3.31Å; S476-Y480 WeakPolarHBondContact O-CB 3.4Å; S476-Y480 PolarHBondContact O-N 3.32Å; G477-Y480 PolarHBondContact O-N 3.1Å; Y480-W482 VanDerWaalsContact C-N 3.33Å; Y480-W482 PolarHBondContact O-N 3.15Å; Y480-M483 PolarHBondContact O-N 2.95Å; Y480-W484 WeakPolarHBondContact O-CB 3.21Å; Y480-W484 PolarHBondContact O-N 2.96Å
481	D	86.5	Confident	80.4	Confident	7 Å²	7	85.5 Å²	85.5	4%	0.037	42%	0.42	C	S	.	.	H	α-helix	trans	-65.6	-34.1	177.5	-178.3	95.8	0	0	0	112.4	S275 Y279 R420 G477 S485	S275-D481 VanDerWaalsContact CB-OD1 3.24Å; S275-D481 WeakPolarHBondContact CB-OD1 3.38Å; S275-D481 PolarHBondContact OG-OD1 2.59Å; Y279-D481 HydrophobicContact CE2-CB 3.81Å; Y279-D481 WeakPolarHBondContact CE2-OD2 3.43Å; Y279-D481 PolarHBondContact OH-OD2 3.33Å; R420-D481 IonicContact CZ-OD2 3.93Å; R420-D481 VanDerWaalsContact CZ-OD2 3.26Å; R420-D481 IonicContact NH1-OD2 3.95Å; R420-D481 PolarHBondContact NH1-OD2 3.08Å; R420-D481 IonicContact NH2-OD2 2.93Å; R420-D481 PolarHBondContact NH2-OD2 3.19Å; G477-D481 PolarHBondContact O-N 3.01Å; D481-S485 WeakPolarHBondContact O-CB 3.38Å; D481-S485 PolarHBondContact O-N 2.86Å; D481-S485 PolarHBondContact O-OG 3.35Å
482	W	83.2	Confident	77.7	Confident	114 Å²	114	91.6 Å²	91.6	43%	0.432	46%	0.46	S	S	.	.	H	α-helix	trans	-68.6	-39.7	173.8	-176.8	64.4	0	0	0	112.7	Y421 V478 I479 Y480 S485 R486	Y421-W482 AromaticContact CD1-CD1 3.9Å; Y421-W482 HydrophobicContact CE1-CB 4.25Å; Y421-W482 AromaticContact CE1-CD1 3.59Å; Y421-W482 HydrophobicContact CE1-CG 4.31Å; Y421-W482 AromaticContact CZ-CD1 3.92Å; V478-W482 WeakPolarHBondContact O-CB 3.3Å; V478-W482 PolarHBondContact O-N 2.8Å; I479-W482 PolarHBondContact O-N 2.84Å; Y480-W482 VanDerWaalsContact C-N 3.33Å; Y480-W482 PolarHBondContact O-N 3.15Å; W482-S485 PolarHBondContact O-OG 3.36Å; W482-R486 WeakPolarHBondContact O-CB 3.19Å; W482-R486 WeakPolarHBondContact O-CG 2.98Å; W482-R486 PolarHBondContact O-N 3.46Å
483	M	85.6	Confident	76.8	Confident	117 Å²	117	88.8 Å²	88.8	58%	0.576	45%	0.451	S	S	*	.	H	α-helix	trans	-69.9	-39	174.5	-74.2	-178.5	65.2	0	0	112.1	I479 Y480 V487	I479-M483 HydrophobicContact CG2-CG 4.34Å; I479-M483 HydrophobicContact CG2-SD 3.91Å; I479-M483 WeakPolarHBondContact O-CB 3.5Å; I479-M483 WeakPolarHBondContact O-CG 3.48Å; I479-M483 PolarHBondContact O-N 3.37Å; Y480-M483 PolarHBondContact O-N 2.95Å; M483-V487 PolarHBondContact O-N 3.41Å
484	W	82.5	Confident	75.9	Confident	164 Å²	164	88.1 Å²	88.1	62%	0.621	44%	0.442	S	S	*	.	H	α-helix	trans	-69.3	-45.6	-180	-171.1	-94	0	0	0	112.2	Y480 R486 V487 S488	Y480-W484 WeakPolarHBondContact O-CB 3.21Å; Y480-W484 PolarHBondContact O-N 2.96Å; W484-R486 VanDerWaalsContact C-N 3.29Å; W484-R486 PolarHBondContact O-N 3.07Å; W484-V487 PolarHBondContact O-N 3.17Å; W484-S488 PolarHBondContact O-N 3.2Å; W484-S488 VanDerWaalsContact O-N 3.14Å
485	S	74.6	Confident	74.9	Confident	17 Å²	17	92.4 Å²	92.4	12%	0.119	46%	0.462	C	S	.	.	H	α-helix	trans	-62.5	-35.4	178.1	50.8	0	0	0	0	112.6	Y421 D481 W482 V487 S488 D489	Y421-S485 PolarHBondContact OH-OG 3.23Å; D481-S485 WeakPolarHBondContact O-CB 3.38Å; D481-S485 PolarHBondContact O-N 2.86Å; D481-S485 PolarHBondContact O-OG 3.35Å; W482-S485 PolarHBondContact O-OG 3.36Å; S485-V487 VanDerWaalsContact C-N 3.26Å; S485-V487 PolarHBondContact O-N 3.5Å; S485-S488 WeakPolarHBondContact CA-OG 3.4Å; S485-S488 PolarHBondContact O-N 3.15Å; S485-S488 PolarHBondContact O-OG 3.13Å; S485-D489 WeakPolarHBondContact O-CB 3.07Å; S485-D489 PolarHBondContact O-N 3.16Å
486	R	67.8	Low	73.8	Confident	151 Å²	151	94.8 Å²	94.8	57%	0.57	47%	0.473	S	S	*	.	H	α-helix	trans	-60.1	-27.9	171.5	-76.6	-78.7	-142.5	165.2	8.9	114.8	W482 W484 Q490	W482-R486 WeakPolarHBondContact O-CB 3.19Å; W482-R486 WeakPolarHBondContact O-CG 2.98Å; W482-R486 PolarHBondContact O-N 3.46Å; W484-R486 VanDerWaalsContact C-N 3.29Å; W484-R486 PolarHBondContact O-N 3.07Å; R486-Q490 WeakPolarHBondContact O-CG 3.48Å
487	V	68.8	Low	72.6	Confident	74 Å²	74	97.3 Å²	97.3	45%	0.448	48%	0.479	S	S	.	.	H	α-helix	trans	-84	-45	177.9	175.3	0	0	0	0	110.1	M483 W484 S485 D489 Q490 D491	M483-V487 PolarHBondContact O-N 3.41Å; W484-V487 PolarHBondContact O-N 3.17Å; S485-V487 VanDerWaalsContact C-N 3.26Å; S485-V487 PolarHBondContact O-N 3.5Å; V487-D489 PolarHBondContact O-N 2.89Å; V487-Q490 PolarHBondContact O-N 3.17Å; V487-D491 PolarHBondContact O-N 2.81Å
488	S	61.5	Low	71.3	Confident	52 Å²	52	102.4 Å²	102.4	36%	0.364	50%	0.497	S	S	.	.	H	α-helix	trans	-61.7	-30.1	176.4	55.4	0	0	0	0	113.4	W484 S485 Q490	W484-S488 PolarHBondContact O-N 3.2Å; W484-S488 VanDerWaalsContact O-N 3.14Å; S485-S488 WeakPolarHBondContact CA-OG 3.4Å; S485-S488 PolarHBondContact O-N 3.15Å; S485-S488 PolarHBondContact O-OG 3.13Å; S488-Q490 PolarHBondContact O-N 3.31Å
489	D	56.4	Low	70	Confident	123 Å²	123	109.1 Å²	109.1	66%	0.658	53%	0.529	S	S	*	.	T	Hydrogen-bonded Turn	trans	-77	4	173.9	-66.2	-8.9	0	0	0	113.4	S485 V487	S485-D489 WeakPolarHBondContact O-CB 3.07Å; S485-D489 PolarHBondContact O-N 3.16Å; V487-D489 PolarHBondContact O-N 2.89Å
490	Q	50.6	Low	68.4	Low	162 Å²	162	111.5 Å²	111.5	76%	0.757	54%	0.539	S	S	*	.	T	Hydrogen-bonded Turn	trans	-114.9	-13.1	174.4	-70	-169.3	-45.4	0	0	114.1	R486 V487 S488 V492	R486-Q490 WeakPolarHBondContact O-CG 3.48Å; V487-Q490 PolarHBondContact O-N 3.17Å; S488-Q490 PolarHBondContact O-N 3.31Å; Q490-V492 VanDerWaalsContact C-N 3.35Å
491	D	43.3	Very low	66.7	Low	135 Å²	135	108.3 Å²	108.3	72%	0.722	54%	0.535	S	S	*	.			trans	-94.4	14.2	177.1	-69.6	-41.1	0	0	0	112.7	V487	V487-D491 PolarHBondContact O-N 2.81Å
492	V	39.2	Very low	64.9	Low	184 Å²	184	117.5 Å²	117.5	100%	1.115	58%	0.58	S	S	*	*			trans	-134.8	0	-177.1	-177.1	0	0	0	0	111	Q490	Q490-V492 VanDerWaalsContact C-N 3.35Å

Retrieved 492 of 492 residues in 969.2 ms (Link to these results)

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